>O06745|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis (strain 168)|Swiss-Prot
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTRAKEFIS
VHHERTEPGLDEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMAHAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>Q9SE60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabidopsis thaliana|Swiss-Prot
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGSTA
DLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEADGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMNL
GLIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPHGRWGDSHSA
AYSTLSDYQFARPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPE
TKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNYINGDIFSVFA
>Q9SE94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zea mays|Swiss-Prot
MKVIEKILEAAGDGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIGILMNL
GLIEESKVSRPLPWRPATNVFRVKEDVRPIFWANRPKSYLKRTLGWDQYPHGRWGDSRNP
SYGALTDHQFTRPRGRGKKLQEEWAVPLKSVEDISERFTNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVNINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLD
QLIEKIKAFPSLTYIAVNKDGETFSNISPNAVNAVTWGVFPGKEIIQPTVVDHASFMVWK
DEAFEIWTRGWGCMFPEGDSSRELLEKVQKTYYLVSLVDNDYVQGDLFAAFKI
>Q10258|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schizosaccharomyces pombe (strain 972 / ATCC 24843)|Swiss-Prot
MKISDKLLHPDWKEKVTYSYEFFPPKTSTGVQNLYNRIDRMKTWGRPMFVDVTWGAGGTS
SELTPGIVNVIQTDFEVDTCMHLTCTNMSTEMIDAALKRAHETGCRNILALRGDPVKDTD
WTEGESGFRYASDLVRYIRTHYNDEFCIGVAGYPEGYSPDDDIDESIKHLKLKVDEGADF
IVTQMFYDVDNFIAWVDKVRAAGINIPIFPGIMPIQAWDSFIRRAKWSGVKIPQHFMDTL
VPVKDDDEGVRERGVELIVEMCRKLIASGITRLHFYTMNLEKAVKMIIERLGLLDENLAP
IVDTNNVELTNASSQDRRINEGVRPIFWRTRNESYVSRTDQWDELPHGRWGDSRSPAFGE
FDAIRYGLRMSPKEITTSWGSPKSYSEIGDLFARYCEKKISSLPWSDLPISDEADLIRDQ
LLSMNRNAFLTINSQPALNGEKSSHPVFGWGPPNGYVFQKPYVEFFVHPSLLNELKETVK
KLNSVSYFVTNKNGDLDTNSQYEIPNAVTWGVFPNREIIQPTIVESTSFLAWKDEAYSLG
MEWANAYSPDSISRKLLVSMMKEWFLCVIVDNDFQNGQSLFDVFNKMRSLKDIHPELYYA
NAS
>P46151|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)|Swiss-Prot
MSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKT
LTLASLAQQTLNIPVCMHLTCTNTEKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVE
AGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
AILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETVANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWET
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKA
WRDEAFSIWSEWAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETDELWEMLLDQA
>O80585|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabidopsis thaliana|Swiss-Prot
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFDCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIGENGLASNEAYQSDLEYLK
KKIDAGADLIVTQLFYDTDIFLKFVNDCRQIGISCPIVPGIMPINNYRGFLRMTGFCKTK
IPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKMLAHGVKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGNLKSSPWSELDGLQPE
TRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLD
AVVEKCKALPSITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWK
DEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIFAVFADL
>O74927|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schizosaccharomyces pombe (strain 972 / ATCC 24843)|Swiss-Prot
MKIVDLIDKIPNGNAFYSFEYFPPKTTVGLENLSSRITRMSRNMMPLFSSVTWGTAGSTA
EVSIYLAKMLEQHHKIPACLHLTCTNVDKAIIDKALETAKEYGIRNILALRGDPPLNSDH
WEGKVSEFEHAVDLVRYIREKYGDYFCIGVAAYPEGHVDSNVPELSKDPLRDIPFLIEKV
EAGADFIITQIFYEPEAFIKFENFVRNHSSNALRNIPIIPAIMPIQSYGSLKRMTRLCGC
SVPSSLMQRLNAAKPDDEAIKNIGVEHIVDMIKKIMDNVQGRVHGFHFCTLNLERSVALI
LKNSGLLTKRWKQVESEMEDEKLLRTTRKRLSLDEPAELHNQVVVPSQQPVADKSSNLFV
TSKQSSVSGHKDNLTEEAPFSVSEGSGVLGRQANWDDFTNGRFGDPRSPAYGEIDGYGPT
LHFPPSEALKLWGYPVDESDITSLFQKHIMSDISAIPWIDEPVEVETKTIAKYLLKLNGN
SWWTVGSQPAVNGAPSADPVFGWGPKGGRVFQKAFVECFVNGKDLKDFITKWHDNPQVTY
YAGNNKSEFLTNAPKDGASAVTWGVYPGREIIQSTIIAEVSFKAWLSESFQVWGEWANLY
SKNTPSRKLLENCINDRWLVTVIHHDFMDKNGLWKVLEIDF
>P53128|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)|Swiss-Prot
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRD
AENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDVKLDLEYLKQKID
AGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQH
FSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANKCLELWSTPTSINDVAFLVINYLNGNLKCLPWSDIPIN
DEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL
>Q5I598|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos taurus|Swiss-Prot
MVNEPRGNGSPGPRWEGSSSGSESSRTSSRCSTPGLDPERCERLREKMKRKMDSGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKH
IRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVK
ACSEIGITCPVLPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFQVFAHHLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>Q17693|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis elegans|Swiss-Prot
MTNTGETKVIESHGTIKKIDSLSTMPYCGVETDENAVVEEKITLESGKSWSPKHYELLHE
RIERLIDEKQQFFSLEFFPPRFVNGVPNFLERVERLSEGGSVFVDMTWHMGSDPANVDKV
TSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPGTEL
EDTHQFRALDMIRWIREEYGNYFSIGCAGYPLGHPQAPSYKADLMYLKAKCDAGANFVIT
QLFFEAETFEKFVRDCREIGITQPIIPGIMPIMGYESIKRIAKLSQLEIPQHILDDLEPI
KHDDDAVQKYGTERCIEMCRRLLDNGTAPSIHLYTMNREGSIREILKSLGLWKLEGDRVF
PWKNRSQHPIRCLESVRPIYWSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLS
NLTTVRNADDRLAMFGANIESFEDVKRVFINYITQAPNADGVKVTVLPWTEAETGVQPET
SLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSDK
LIQIIEREFPVRVNYHAINKDSTFDKTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRA
WRDEAYQMWMAQWGDFYPKESKSYGVIKAVHDEFRLVTLVDNDFQKPSVLFDVLQKALDE
LKK
>P42898|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Homo sapiens|Swiss-Prot
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYE
EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNARETEAP
>O67422|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquifex aeolicus (strain VF5)|Swiss-Prot
MKIGDILRKGVFSISFEFFPPKTEEGERQLFETIRKLEKLNPTFVSVTYGAGGSTRDRTR
NIVQKIHEETNLTVMAHLTCIAHTREELIDILQDYKNIGIENILALRGDVPRDKPDWRPP
KGACKYAKELVELIRKEFGDWFSIGVASYPEGHPESPNLEWEVKYFKEKVEAGADFSITQ
MFFVNDYYYRFVEMCKNAGIDISIIPGIMPITNFKQIRKFASLCGATIPQSLIEKLEKVE
DKPEEVKKIGIEFAINQCLDLIEHGVPGLHFYTLNKSDATLKIYEAIKDKIPARST
>P57154|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)|Swiss-Prot
MKNYSQYHQDIMNQKLENIRNNIQCSFEFFPPKNSFLEENLWSTVNRLSLLKPKFFSVTY
GANTGEREKTYDTVQKIYKKTGIITAAHLTCIDSTPHKLKEIAYNYWNSGIKSIVALRGD
TLEKDYRHTMYAVDLVLLLKKIADFDISVAAYPELHPESKNVKSDILNLKKKVDAGASRA
ITQFFFNIESYLRFRDNCIKNKINIDIIPGILPVCNFQKLKRFSSMTNVKIPKWMLDMFN
GLDDDIFTQKIIGSSIAIDMVKKLSCEGVKNFHFYTLNQSDITYSICHILGL
>Q8KA62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)|Swiss-Prot
MNFLHQYYQDIIKKKLENLNDKIQCSFEFFPPKNLDTEKKLFSSVVKLSLLKPFLFSVTY
GANSGERKKTYSIVQRIHKKTGITTAPHLTCVDASLSELKEIAKFYWENGIRSIVALRGD
VPNKSYQHKIYALDLVVLLKKIADFDISVAAYPEIHPESKNAQSDILNLKKKADAGANRA
ITQFFFNVESYLRFRDNCIKNNINIEIIPGILPIYNFEQLKKFSSMTNVSIPKWMFEMFN
GLDEDLETQKIIGSNIVINIVKTLLYEGVKNFHFYTLNKSDVIYSICHMFGL
>Q89B13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)|Swiss-Prot
MKLVYKNYHETLNQHLMNICEKVNISFEFFPPNNILSEKNLWQVIDKLKLLTPKFFSVTH
GTNSKIRATCTSNIVKKIKKYTGIETVPHLTCINSTEEELKVIAKTYWDSGIRHILALRG
DIFNTNCKPKIYAVDLIKLLKSIANFEISVAAYPEVHPEAVNAKYDIINLKRKVEAGATR
AITQFFFNIDCFLRFRDLCVKNNITIDIVPGIFPISNFKQLLKFSSVSNVSIPKWLCCMF
HGLDNDLNTSRIIGSSIAIDMVKVLYSEGIRSFHFYTLNKSEISFAICKILENKS
>P0AEZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli (strain K12)|Swiss-Prot
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>P45208|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)|Swiss-Prot
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DNDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>Q9JZQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis serogroup B (strain MC58)|Swiss-Prot
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>P71319|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium carotovorum subsp. carotovorum|Swiss-Prot
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWESGIRHIVALRGD
LPQEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTTMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>P11003|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)|Swiss-Prot
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>P0AEZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella flexneri|Swiss-Prot
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>G2IQS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. (strain NBRC 103272 / SYK-6)|Swiss-Prot
MATATLDKAALSRLFTDYSLEITPKDVEALENAAHMIPPGTLISVTFLPGAEYEDRARAA
KRIQELGFRPVPHLSARRLIDEADLRTYLDMLKGVIDLKHVFVIAGDPNEPLGIYEDALA
LIDSGILKEYGIEHCGISGYPEGHPDITDEKLAKAMHDKVASLKRQGIDYSIMTQFGFDA
EPVLEWLKQIRSEGIDGPVRIGLAGPASIKTLLRFAARCGVGTSAKVVKKYGLSITSLIG
SAGPDPVIEDLTPVLGPEHGQVHLHFYPFGGLVKTNEWIVNFKGKQGI
>O54235|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lividans|Swiss-Prot
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTNFVD
KCRAGADYAITQMFFQPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>Q60HE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macaca fascicularis|Swiss-Prot
MVNEARGNDSLNPCLEGSASSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDLCVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKQSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYE
EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDALELLNRPTQNEREMEAP
>Q9WU20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mus musculus|Swiss-Prot
MVNEARGSGSPNPRSEGSSSGSESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFS
LEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPVGDHWEAEEGGFSYATDLVKH
IRTEFADYFDICVAGYPRGHPDAESFEDDLKHLKEKVSAGADFIITQLFFEASTFFSFVK
ACTEIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIEL
AVSLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDPRRPLPWALSAHPKRREED
VRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWNDEPLAAETSLMKEELLRVNRLGILT
INSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLNRHPTERETQAP
>Q75HE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryza sativa subsp. japonica|Swiss-Prot
MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLK
QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNL
GLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLD
QLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWK
DEAFEIWSKGWACLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAFKEI
>A0A359IEF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MDKGHETSQKPRNFLACLRDHVLLFDGAMGTMIYERGVYVNQCYDALNIQKPDLILGIHR
DYADAGADALTTNTFGANRFLLKKYGYEERTVEINRKGAELARQIAGEELFVAGSMGPPP
DRMEPLGKLTVRELREAYHEQAEALIHGGADILILETFSDLGMICEIIREIKSAFPKVPL
IGQMTVDKEGRTSLGSTPEIFASEIVRAGADVVGVNCSLGPSTMLEVAERIFRISPIPVS
AMPNAGLPQRVDGRNIYFSSPEYFSEYTRRFVQVGVRIVGGCCGTTPDFIRSMRNALRSI
QPRKRIEITSLPPQHDEDVDLIPTSKKSRLAEKISRGEFVTTVEIVPPQGPDPRKAVEQS
RILFESGVDAINIPDGPRALSRMASSYLSLIIQQETGGEVIQHFTCRDRNLLGMVGDFLG
AYAAGIRNILIITGDPPKMGTFPDASAVFDVDSIGLTRVASILNHGRDLGGNVLKKATGF
FIGVGANPGAINPEEEIRRLEEKRDSGAEYIMTQPVFDPEIFLTFMDRIRHINLPVIAGI
WPLVSVRNAEFMNNEVPGANVPDWVMERLKRSRTRDEARETGLAIARETLRILKPYLQGA
QISMPFGNVKYPLEVLKEVLS
>A0A375GRY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus taiwanensis|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVRAGADSAITQYFYNADAYFRFVD
DVRALGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A5E7NDA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAKYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLKQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLANFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A2E3VL20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda sp|TrEMBL
MKITDHIKKANGETLFSFEIVPPVKGKSIQELYTNIDPLMEFKPPFIDVTTSREEYVYKE
KDGLLDKKLTRTRPGTLGICASLKHKYDVDTVPHVLCGGFTKEETEYLLVDCQYLEIENV
MALRGDARKEEKYFTPTKGGHQYATDLVKQIQDINEGNYLHDTIESSDLSSFCIGVAGYP
EKHMEAPSLQSDLKRLKQKVDLGADYVVTQMFFDNQKFFAFVKAAREMGINVPIIPGIKP
IAVKRHLQVLPHVFSIDLPEDLINAVEACKDNQAVRQVGVEWAIQQSKELREAGVPVLHY
YSMGKSDNVKAIAKELF
>A0A174VPK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides caccae|TrEMBL
MKVIDLINNSKKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEEAPNIESDLYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAERVGIEWCVTQCKELMSHGAPSIHF
YSIGAVDSIKEVAKIIY
>A0A4Q5KR84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliivibrio finisterrensis|TrEMBL
MAYSHASHLESLNQNIAELDGNINVSFEFFPPSSEKMEETLWNSIHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLIAAPHLTCIDASRSELVDIANDYWANGIKDIVALRGD
IPPGGGTPEMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQASRFAKMNNVKIPGWMAQQFE
GLDDDPVTRQMVGASHAIDMTRVLSREGVKDFHFYTLNRAEHTYALCHTLGVRPKG
>A0A1I3GAM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium brachiatum|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTDEMEKILWSSIERLAPLQPKFVSVTYGAGGSTR
ERTHNTVARMIRETTLKPAAHLTCVDASREEIDAVVQAYWDVGVRHIVALRGDPADGVGH
AYKPHPEGYATTAELVEGIKRIGDFKVSVSAYPEKHPEAATLEADIDALKAKVDAGADQA
ITQFFFENEVYLRYLEKVRAAGITIPIIPGILTVQNFKQAANFARRTGASVPYWLAARFE
GLDNDVETRRLVAAAVAAEQVLDLVDEGVQDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AEKAAA
>A0A3M6VCW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peronospora effusa|TrEMBL
MGKIIESILSVYSARADDASARPTISFEFFPAKTNAGIFNLLTRVEEMGLTLQPTFVTLT
WRSAFKDETLWLRIGAHIQNEFQMDILLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGSERWAPVEGGMSNAKDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIQWIADCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPEQVLMDLNAIKNDDAAVRCYGTQLAVKTCQRLLAAGVHSLHFYTMNLAAT
VTQVLDDLQLLPARNQRELPWQSTLHRLAVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKVQRAKLWGTPQTEEDVWNVFVRFIDGQVKQLPWCEQ
ALSLESAAISENLQWLNSNGFLTINSQPRVNGAPSSDKSVGWGGDDGVVFQKAYVEFFVA
PEKMAHLVKVMRRDYPQLSFHALNRRGDEHRNTPLHSVTAVTWGVFPGIEIVQPTVVDAD
SFAAWKDEAFELWQTQWASAYPEGSRSREVVQHIYDTYFLVNIVDNDYANDESDIFSIFT
RIITEAMNKDQLRARVLELATRREKMFDTLASFQTLQDEQNEELRAAHSELASVRSENLQ
LKEKIRQLQARLALTSL
>A0A228J542|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia aenigmatica|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAAYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLVDAGVPGLHFYTLNAAAATKTVCERLV
>A0A081TQN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLYQRNRLRRRPGTVAVAAAIQNKYNMTVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGHHHALELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFDFVERVHQAGIHIPIIPGIKP
FKKLSQLSMVPKTFKVDLPEELTQEALKCKTDEEARKVGIEWCINQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A3R6KXB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides distasonis|TrEMBL
MKVIDLIRDSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNKKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIVHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A7Y3F0J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MISKHVPISFEFFPPRTDAQNLVLESTWQRLSRLHPRYLSVTFGAGGSTLDATLQTVSDL
IERSGVPVAPHISCMARDRDMLLRLLQSYKEAGVERLVVLRGDRPEGMSGPGPFQYASDL
VRFVQESFPDEFHIEVGCYPEFHPESASPETEFRYFKEKVDAGADGATTQYFYNTDCYFQ
FLDDCERNGIDIPITPGIMPITNYESLNRFSAMCGAEIPRWIRKRLEAYGDDIASIREFG
LDVVSKLCERLLLGGAPGLHIYTLNRANATMRLWQRLHHL
>A0A0H5B8L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastochloris viridis|TrEMBL
MTGSSSRPSRFTGGPGIKVSFEFFPPKTAEMDLQLWESITRLAPLGPDFVSVTYGAGGST
RARTHAIVKRIVDDTLLKPAAHLTCVAATCDEIDAVIGDYWAAGVRHIVALRGDPPAGPG
SRYEPHPGGYGCSADLVAGIKRIADFEVSVSAYPEKHPESGSIDLDLDVLKAKIDAGAGR
AISQFFFDNAHFLRYRDLVAARGISIPIVPGILPVLNFKQAKSFAERCGTEMPGWLARRF
EGLDDDAKTRQLIAAAVAAEQVLDLVDHGVTEFHFYTMNRADLVYAVCHLLGLRPEAAQA
AA
>A0A2G1XQP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cinnamoneus|TrEMBL
MALGTASTRTDHALTVRELLASGERSYSFEFAAPKTEKGERTLWNAIRRIEAVGPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVDHSLAELRNVIGQYADVGIRNMLALR
GDPPGDPMGEWVRHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPDLAERILAVKDDSAAVRSVGIEYATDLCARLMAEEIPGFHFITLNHSTATLEIYENLG
LHQRS
>A0A2N8HZL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia muciniphila|TrEMBL
MHLRERLQSGAGPSLSFEFFPPKNEQAASALYQTIRELEPYRPSFVSVTYGAGGSTRELT
REVVLRIQHESRIPTVPHLTCVGHSREEVWNILDQYARAGVRAVLALRGDPPRGAKDYNR
DADVFRHAADLVTFIREYNESGRHPDPDGFAIGVAGFPEGHPATPNRLREMDFLKAKVDA
GADYICTQLFFDNHSFLDYRERCLLAGIKVPILAGIMPVTSLSGMNRMAELSGGTCFPAR
LLKALKRAGSNPDAIQEVGIQYASSQCAELLDSDVDGIHFYTLNQSRATREIYRNLGLKD
SLQLLEHGEDK
>A0A7C1LA19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopseudomonas sabulinigri|TrEMBL
MNTALNKPISFEFFPTKTDAGHAKLIAAGHVLAAENPEFFSVTYGAGGSTRDRTRKTVLQ
LDSEVKVATAPHLSCVGDSLEDLRTLLGEYQEAGIKRIVALRGDLPSGMGQASGELRYAN
ELVEFIRKETGNQFTIEVAAYPEAHPQAQHFEADLKNFVRKVQAGADSAITQYFFNADCY
FHFVERARKAGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSDSICA
FGTEVISQMCERLLEGGAPGLHFYTLNQAEPSLDILRNLRTN
>A0A8F6CM42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcus capsulatus|TrEMBL
MKTQLKYPREFSFEFFPPKTEEATENLRRTLTKLAPLKPRFCSVTFGAGGSTREKTFETA
LEIQQTTGIECAPHLSCIASTRRSIREILEAYRSHGIRHIVALRGDMPSGMLSAGEFRHA
NELVEFIRSETGSHFHIEVACYPEVHPQAASAESDLKNFKRKVDAGADSAITQYFYNPEA
YFRFVDDCERLGIDIPIVPGIMPITNHSQLVRFSDLCGADIPRWIRKRLEAFGDDRKAIR
AFGLEVVTELCRRLLEQGAPGLHFYTLNRAEACLEVWKALGLEPA
>A0A385C1W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter wuhouensis|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLDDFN
GKGTPVAPHLSCIGDSKQRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQRFCDKARAGANAALTQFFFNPDAYFYFV
DRIQKEGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A169BWS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter tritici|TrEMBL
MSEQRSESEPACPRVPFSFEVYPPRTAAGSLALLRTVDRLTAAGPSFVSVTYGAQGSSRS
ASLGILRYLLERTATPALAHLTCIGSTHEEASRLVREFLEAGVTRFLALRGDRPTGTPEE
AACLGELASAAELVQLIHRVQAEREPYGAVPVPGLPNAQRVDVAARPHAEVAVAAFPNGH
PRSRSRTQDIDVLLAKEAAGASFALTQLFFHAEDYLRFVDRARAAGLRMPIVPGVMPVTS
PARLRRMLELSGEDLPADLAIALDVEPDDEARLRIGVEYAARLIRTVVDGGAPAVHLYAF
NRDEAVLAVLAETGLLPPGSVPPLPTAAVLSTPSPQEPTA
>A0A1N7IAV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium joostei|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELITEVENAKNNEAVKQIGIEWSIAQCKELLDFGVPVL
HFYSMGKSDNIKSIACELF
>A0A2R3IUG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDRTLHTVLQL
DGEVKVPTAPHLSCVGDSKAELRELLGQYRAAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRAETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQYFFNADAYF
YFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSRSIQAF
GEQVISEMCERLLQGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A380AVE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia liquefaciens|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLDAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGSGKPDMYATDLVALLKEVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAA
>A0A8H6PZC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus felis|TrEMBL
MHVQDMLADNEAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEA
WEATEGGLRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNSDVDQLIDHLKEKVDAGSSF
VVTQMFYDTDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEAL
EPVKNDDAAVKEIGKKLIADMCRRLLAAGIKHLHFYTMNLAQATQAVLEELKLIPSEETP
LQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSIRDVTQIFVRYLEGKLDRLPWSDSPISSEANAIKDNLVQ
LNSRGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNP
DLTYHAVGKKGEFRTNTRDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQDMMDNWYLVNIVNNDFHNTYDLFDLFDGLEVKDFDVEVVPDTVETK
SQPNGAAPEEVAVKN
>A0A2T8M1K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella anatum|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>T1EFD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helobdella robusta|TrEMBL
MINLKMPQQQQQMEPSTSFKNGEQNENEESISRENSVETFNNNNNELEFPTTKYRCLIDR
INDRIKKNATFCSFEFFPPKTVNGAANLIKICDRLASTMNPLFCDITWKTGGDNCSDAPT
STMTIGSTMLSYCGIDTMMHMTCVGQSRSDIIRILNKAKILGLKNILALRGDLPHNCSSW
QPVDDGFNHAIDLVRFIRKTYGDYFVICVAGYPTGHPDASSYKADLENLKAKVDAGADFI
ITQLFFKTSTFIKFVNDCRSIGITCPILPGIMPIQAYQSLENISRLSKLEVPQEIWDKLH
AVKDNDEAVRNFGIDYAIQMCSQLLNSGVVNGLHFYTLNREYATLAILKSLGLCAVRPQR
PLPWKTSANHVRCMETVRPIFWSSRPESYIYRTSGWEEFPNGRWGNSASASFRDVNEHYL
YHLKSAPSKEELLKMWGAKLESEVDVWHIFECYLLAKENKQGYKVTRIPWSEGGLSSETT
CMLDRLGKINKQGVLTINSQPAVNGAPSTHPIYGWGNPGGYVYQKAYLEFFTSLKYVDRL
KSILNGYPNVNYHIIANHAIDITNCHELQPSALTWGVFSNMEIVQPTVYDPVAFKYWKDE
AFGLWKSYWGAIYDEGSESRNVIDTIHDEYCLVNLIDNEFVKESCLFNILEEMLQTN
>A0A5L8JYU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter fetus|TrEMBL
MLKKKIKDNTPGILLYGLTPPKLNLTHEEAIIVAKKQLERLENRGIDGLVIYDLQDESNR
NKSERTFEFCGTIKPEIYHKEFLKLAYPAVIYKAVGNYTQDEFCRFLNDSGENLSVFVGA
SSKKDSPKLSLDMAYKLKKEQGRDITLGGICIPERHEKKGDEDLRVAGKTIKGCEFFITQ
AVYNLENAKRFLDDYSNLNIKKVPIIFTFTPCGSLKTLEFMRWLGISVPKQFENRLFKSD
DPLKASISLSLDMFEFLFKYGKAKGISIGANVESISTRKVEIEASVELVNGIKSIIS
>A0A5M3PL29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter salsuginis|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYKEHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A2A6LX08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium fredii|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMEIQLFQTVADLSSFAPAFQTVTYGAGGSTKAR
SLTTVKRMIGEMGLRNTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGSA
YQPFPGGYESSAALVNALRARGDFEISVSAYPEKHPESSDVAADIDMLKRKVDSGATRAI
TQFFFDNDDFERYLERVRRAGVQIPVVPGILPINNLTQVIRFAGLCGSKVPEAIVSRLGH
LDDQPEERFKEASHIAAEQIVDLARRGVRDFHLYTMNRSPLIAAVCDLVGYGRRPANHTA
APSYRAVATA
>A0A858N1H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster clostridioformis|TrEMBL
MKTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTREDVLLILEQLKEQKIENILALRGDRVPDREPAGDF
RYASDLVEFIKLHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFRERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFISVMERYGDNPIAM
RDAGIAYAVDQIVDLVAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>A0A6I6G3H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus terrae subsp. cibarius|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTEEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASREELQHIAQDYWQSGIRHIVALRGD
LPDNTQKPDMYATDLVHLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMFD
GLDNDPETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPELVKA
>A0A2K3N6X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trifolium pratense|TrEMBL
VDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIP
AEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMSLGL
IEESKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSGNPSY
GALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQPETK
IINEHLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKLDAL
VEKTKDRPFLTYMAVNKEGVWKSNVGQTDVNAVTWGVFPAKEIIXRAKEIIQPTIVDPVS
FSVWKDEAFEIWSRAWASLYPEADASRKLVEEVGSSYFLVSLVDNDYANGDLFGLLADF
>A0A646HEL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHSHATDLLKQVNQFNEGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQMGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDDDAKQLGIEWTTAQVQDLFEHGYNNVH
FFTVSAVDSVKQIAKILF
>A0A1V2LPJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pichia kudriavzevii|TrEMBL
MSVKITDKIASLGKDEPFFSLEFFPPKTESGMRNLYARLGRMSLLGPLFVTVTWGAGGTT
AEKTTDLAVTCQEELGLTTCMHLTCTNTPKSVIDDALKKAKASGIRNILALRGDPARDTS
ISHGIGEFKYAVDLVRYIREQYGDYFCIGVAGYPEGHADGSFEELTQDPRKDMPFLVEKI
KAGADFIITQLFFDVDKFADFEALVRSQPELRDTVIIPGLLPINGYNIFQRASKLSHASI
PSKLLAKFPTEVQNDDDVVKDIGVDVLVDIIDQIYKKTDNRVKGIHFYTLNLEKSIAQIV
NKSDHLYKVVAKKESEIEADESSSDDDIDDAITTAKRAAYANRFNTTNKVISDIKASTSL
KMQHSNSSSSQLKKLISISAGHGVLGKDATWDDFPNGRFGDSRSPAYGEIDGYGPSLKVT
STKAYELWGYPKTKKDISKLFVNYLLKKLNCLPWSELSLSPETALIQEELINLNELYYFT
VASQPAVNCASSQDKIIGWGPSNGYIYQKAFVEMFVSKKDWNEKLLPKISKCGSSVSYYY
ADSKNYFDTNLPPNASNCVTWGVFPNREIVQTTIIEEESFKAWTEEAFEIWKEWKLLYKK
DSDSAKLIDTILNEYYLVTIIHHEYPNESALWELLLDDE
>A0A3A5LAG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Legionella taurinensis|TrEMBL
MKTLRDKIMEASQPVIFYELLPPTGEKAANTDAYIDCAIDLLTSTPVNIDGVNIPEIRDE
NKGEQRTDEFVPKMDPRHFAERLEQAYRNINVVLNHCTVYEGWEEQKAWLEHSANQTNLR
ALILVGGSSSKIDYIGPSVIEMLQYIRTHYTKDLFCGGITIQTRRSHDAVRDEPHRLLAK
SLNGMEFFTSQIIYDPISMKFLLRDYAYACREEGIEPKRIFLSFAPVSSHKDLHFLRWLG
VFIPKTVEDELFKADIGIGWRSLKIATNNLLEILQFMHKEKIQVPLGLNIEHVSRHNFEL
SLEFVERLGDLYYSHVSKLP
>A0A7W1DFT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacteraceae bacterium|TrEMBL
MSPNLRELLATRVLIGDGAVGTLLGERGVGFGHPYARANLSHPGMVNDIHVEYLRAGADV
IETNTFAANRFKLETHDLEERVREVNAEGASLARKAARAAAGTGDRALVLGAIGPLGRPL
APVGPVSPERAKSVFLEQAEALLEGGADAILLETFTDLVELRLAYEAVGALGAPVLAYKT
FVEDGETLAEGLPGRAAREISSWGADLTGANCTVGPQRMVEIIGQMADAAGPVAALPNPG
LPQLVRGQIRFSKDVDHFAEYGVKLAEAGARLVGGCCGTTPAHVKALSEALRDFRVEGTG
ARRRAVMVEQPGQAYVLAEPVSEFAERLRTGFAVTVEVDLPRGNAIEQVVEAARRLKERG
VHAIDISDGARARLRMHPVAAARIVQDEAGIEVVAHISCRDRNIIGLQADLLGAAALGVK
NILAVTGDPAQIGDYPEATSVFDTDSVGLVHILSRMNRGEDLAGNPIGEPPGFLVGASFN
PTAEDLDEEVEKLRRKVEAGAHAFWTQPVFEIGALENALERVGDDGVCILLGLMPLRSAR
QAEFLHHEVPGINIPKHVREKLAALSPEDAPKYGVEVAQRLLVAARPLIGGAYIMPPASA
PDLAGDVLEAISLPAGRR
>A0A6B1HC95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MNPPLKLSFEFFPPATDRNEAALWRTVEALTSFGPRFVSVTYGAGGSTRARTDRIVRAIK
RDTGLEPAAHLTCVGAVREEVDAIAKGWWEAGIRHLVALRGDPPKDADRYTPHPGGYENA
AALVAGLRRVADFDIAVAAYPECHPDSTSPEADLDNLKRKLDAGAGCAITQFFFEPATFL
RFRDRACAAGIEAPIVPGILPITNFARAVRFAGSCGATVPAWLAELYRGLDDDPETRSLV
AAAQATELCQRLQAEGVEAFHFYTLNRPALTAAICRRLSVRAPLEEAA
>A0A2V6RR64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MSAPFIERLRERPLLGDGAMGTMLYARGVPLDACFDVLNVNEPKIVQGIHAEYIQAGADW
VETNTFGANRFKLGVHGLAAQVREINLRGVKLARDVRETLGRDIFVLGSIGPLGKYLAPL
GSITPEEARAAFREQAEGLLEGGVDAFVVETFSDLQELRLAVEAVRAITDLPVIASVAFT
QDHVTFLGSTPAEVTRTLRELPIQGLGANCSVGSSTLYEVLEQMLPEAGGLPVSIQPNAG
LPSRIGERLIYVSSPAYMAEYAARMIGAGARLVGGCCGTTADHIRAMREAVDRHVPSRDG
RTAAPRRARVEREAPALITTAAPTLLQRRLEAGEFLVTVELDPPRGHNIEKLVQGAKLLK
ERGVEIVDINDGSLGRVRMSVLPTAILVREATGLDINMHFTCRDRNLMGIQADVLGAHAL
DIRNILAMTGDPPRGGDYVNATAVFDVDAIGLIRILTEMNEGRDATGNSVGEPTAFCVGA
ALDPAAADPSREMERFLAKAEAGARWCQTQPIYDLEVLERFFARTRPPIPVVVGLLPLHS
SRHAEFLHNEVPGITIPDAVRGRMREAGERGLRVGIETAQELVRHLRGRYAGAYLMPSFG
RFEVVAEVLDALQ
>A0A0C4EVH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia triticina (isolate 1-1 / race 1 (BBBD))|TrEMBL
MKISQKLAAAESENRISWSFEYFPPKTDNGLTNLYDRIYRMSQLGPIFIDITWGAGGSTS
NLTTEFVKTAHEQFGLETCMHLTCTNMPKERIDTALREAYEFGCENILALRGDPPKGSSE
WTATEGGFEHAIDLVRHIRAQYGDHFDIAVAGFPEGHMHSSLSREQETIYLKEKIDAGAN
FIFTQMFYDVDIFIDWVREIRAAGITVPVIPGLMPIQSWAQFKRVTNFSKTIVPQYFLDK
LEPIQSDDQAVREAGTKLVADMCRKILNSDLGIRILHFYTMNLERGTKMILDELNLNPSR
DITNPLPWKMSLLGKRRSESIRPIFWANRAKSYLSRTETWDEFPNGRWGDSRSPAYGELD
GYGININSATIETLKGLKKFPTSLEDLARIFANYCGARFPGEEPVKYLPWSDIPLSEETN
KIEDVLVKINKRGFLTINSQPAVDGAKSSDPVHGWGPRGGYVYQKAYLEFFCCPEKFQSL
TERLEKDPDVTYYAVTKTGDLVTNNTRPGPNAVTWGVFPGKEIVQPTIVELVSFIAWKDE
AFELGHQWAELYKELAPESSQFIHEIMDSWYLVNIVNNDFRKSNDDSDDSALFQFFGPEP
VIVKEDNVPSTNGVHHTNGIAKVNGSSTPAVSEVNGDLKNLAI
>A0A1V0GT03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus yeei|TrEMBL
MTTPALSFEFFPPKTLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETMQIVADYAAAGVHEIVALRGDAPQGQDRFAPHPQGFANSV
ELIEAIAARGDMTIRCGAYPEPHPESPDTAADVAWLKRKTDAGATSAITQFFFDAETFFR
FRDQCERAGITARIIPGILPIQSWAGTRRFAERCGTSVPAWAEDAFAAAGKAGEAQLALE
TCVQLCSDLVAGGVDSLHFYTLNKPDLVQKVCAALGVVPPRGAMSDVA
>A0A349Z605|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPGNEKMENTLWKSVERLAPLNPAYMSVTYGA
NSGERDRTHDVVKRIQQQTGVTAAPHLTCVDATADELRQIARDYWDSGIRRIVALRGDLP
KGVEKTDMYASDLVALLKEVHDFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTGVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKLYEGL
DADDQTTRNLLGANIAMEQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVKPQNAG
>A0A349R1Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp|TrEMBL
MKIIDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTDGGHAFATDLLEQVTDMNKGKYLHEDIITSEKTDFCIGVAGY
PEKHFESPNFNTDFKYLKQKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVAACKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLA
>A0A6V7BKG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. vitians|TrEMBL
MIYPDTPSLASTVTDAYSLEVSATDIPGLTAAAPRIMRGSTIAIPYLPSQDNDARLAAAQ
SVRALGFAPMPHLSARRIASLEELHAFVRRAVDDAGVERCLVIAGDAPSAIGPFPDSVSL
ITTGVFERAGIKTIGVAGHPEGHPGMPATDQWDVLERKCRSIAERGMAPLIVTQFAFDAD
IVLTWLEALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACASMLSKYGISIGKLFGS
AGPDRFVDRLATGLTEAHGDVSLHFFPFGGIAQSVAWVEQYRSRTAAHIL
>E1BXL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallus gallus|TrEMBL
MVNENQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCSNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVHGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETSLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPPQQ
>A0A2G2NIH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp|TrEMBL
MTLVSERQPFNRPDEEAAARFRDLVRSASIEATPRQILTTEHLPDLLPAGTCVYVPFLPK
GQFSDTLEASRRLLDLGMQPVPHVPARMAQSRGQLRDWLAQLDESGVDRLLLIAGDSDAV
AGPFPDTLAVLESGLLAQFRFHGIGVAAHPDGHPMADRATLAKALSVKREYARTTATRLW
VVTQFTFDADVVIDWLQGLGNILEEVPVYIGMAGPTRVKTLIAYAAMCGVGASARMLLRR
PGSARMLGAWKPDDMVRALVQYCLENPETLLRGIHLFPFGGLRQSAQWIRDHSGSCENNR
EAVP
>A0A2C6CIZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. polymorphum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEIGD
FNYAKDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNKPGTAKKIIDATGIIRK
>A0A7W8MK97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus metallilatus|TrEMBL
MTRVSIELVPRSRSSLKAELEVVARHLPGICTVNVPDLTRFSTRSWVGCSFARPHYRAIP
HVRAVDLNPVEPLPMAEALTVSGIDEVLVITGDAPADMSARVYDVDAVRAIRRFRRELPH
VRVYAGLDPYRQSFAHERDYLERKLDAGACGFFTQPFFDLRLMDAYADLIPQGAEIWWGA
TTVTGDATLNYWRARNHAVFPRTFTPTLEWNRTFAAQALAFARERGQHMYFMPVKADVRA
YLEGIV
>A0A538L285|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDEILEDRRPVFSFEFFPPKTKPGDAQLRAALGDLRQDEPAYVSVTYGAGGSTRDRTV
EITKWIKQDLAIEAMAHLSCVGEPVSRLREILDEIRDAGIDNVLALRGDPPRGETEWRPH
PEGLHSSPELIELIASEYDFCIGAACFPEVHPEAPDLETDLRFCKRKVDSGASFLITQLF
FDNQLYFDFVPEARAMGIDVPIIPGIIPVTNYAQIKRFTEICGASIPAGLERELAERADF
PDAVKDLGVAYATAQCGELLARGAPGIHFYTLNRSPATRAILAALRAMRPWDRTEAVPA
>S5K6P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDDVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A6J1AXI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herrania umbratica|TrEMBL
MKVIEKIRTLQEEQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGSDSVATPEAYQNDLEYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPADIADTLERIKDNDEAVKSYGIQVGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRFLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSQN
PSYGALTDYQFMRPRARNKKLQEEWATPLKSIDDIQEKFKSYCLGKLKNSPWSELDGLQP
ETKIIHEQLGKINLEGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKL
DALVAKCKALSFITYVAVNKNGDLISNIGAADVNAVTWGVFPAKEIIQPTVVDPASFMVW
KDEAFEIWSRTWASWYSDSDPEGVQSKKLLEEVQSKYYLVSLVDNNYISGNIFAVFEDI
>A0A3H2W3H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDKAYLAVYPNASLPEVQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLESTKPVLEKEVRPIL
ELVPEEVEDEESGERLLDKVKERLTILVELDPPRTFDTSKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYVQNKQQLQIASK
>A0A6I2VSY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTNIGESVTYSFEFFPPKDQEGEERLWSAISALEPIAPDFISVTYGAGGSTRDRTIRITS
EITEHTKLPVVAHLTCVGSTRNELIEILERYKAAGIHNILALRGDPTGGPRAPWTPTSGG
LNHADELVSLAAEFGGFTIGVAAFPDGHPASNGDFDKDIQTLLRKEAAGATFATTQFFFE
VDKWQALTDNLAKRGSQLPIIAGILPVTNVSQLNRMSELGGTPIPVSIASAFDALKDKPD
DVRKLGVELATKLCEDLLEAGVPGLHFYTMNTSTATQEIFAQIKDKKRS
>A0A7K0QZ15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSLLREKLENSKDLVFTAEFPSVDGGGMASVEKNVARLAPWFDAVNATDNPAAHAHASNT
TTAIAMKMHGLEPIMQIVCRDKNRIAIQADMMGASLHGITNLSLLTGDDVTAGDEHEARR
VFDIDSAQAINIARVMATGTYLSGRAIKPAPDFYIGAVENSAAPPFDYRIQRALKKHRAG
AKFLQLQICYHPDRLEAFCKGVAEIAPDLKLIPTIVIVKGAKPLGFMHDKVPGIDVPSQT
LARVQNASDQSEEVYSLTLELAQHALSLPGVRGLHITDFRHDDSLARFMSDLGRTPRN
>A0A842S4D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MANRPFSKLGEGLAKGEFVLTGELEPEKTCDLSHTIKEANEMAPYVHAANVTDSPLGIVT
INSMAASNIIQRETGLECVWQLTVRDVNKLGIAGMIMGGHALGLRNVLSLTGDHTALGDM
PESKPVFDLDSSTLVKLVREMVDEESINGHEIECPPTFHVGAAANPNADPMGAEILKIGR
KAEAGAEFLQTQVVYDIDRTIEFLTEIKKYKVPVLLGIFPMKSYGIAKGFDTFVPGVSVP
PDILAKWKGIKKNITDKKEKKAAYDEANYEFFKPFITELKKKGLLAGVHCMAVHYTRIFP
KLIEVIKA
>A0A6I3GCT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKKIGEGVTYSFEFFPPKDPEGEERLWSAMGALEPIAPDFISVTYGAGGTTRDRTIRITS
EITQRTHIPTVAHLTCVGSTRDELIEILGRYKQAGIHNILALRGDPTGGPRAPWTPTPGG
LNHADELVTLAAEVGGFTIGVAAFPDGHPASGLDFAEDIEVLLRKEEAGASFATTQFFFE
ADKWKALVDRLAARGSKLPIIAGILPVSNVNQLNRMAELSGVPIPTSIADRFAALKESPE
DVKKLGVEIATQLCEDLLTAGVPGLHFYTMNTSSATREIFAQIKDKKRG
>A0A6I3DV37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSSTTFSVEFFPPKDSDGEERLWAAMADLRALAPDFISVTYGAGGSTRDRTVRITKEITE
KTGIATVAHLTCVGSTKSEIVEILGQYKEAGIKSILALRGDPSQGPSAPWVSTPGGFDHA
DQLVEIAAHTGDFTIGVAAFPDGHPASAGNLDRDVDVLLRKEELGASFATTQFFFESAKW
IALVERLQRKGSSLPIIAGILPITNLKQLKRMAELSGTPIPTKIEKAFLDLGDNPSDVAK
LGVELATHLCDELLDAGVPGLHFYTMNTSSATVDIAKNLGFDSRATR
>A0A6I3GI61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARIADLLAAGRTFSFEFSPPKSAAASMSLGRTIAELEPLGPSFVSVTYGAGGSTREHTR
DTVLWVQRETNVPPMAHLTCVGHTRAEIEDIIATYVEAGIVNVLALAGDAPKDPADARPS
DYTYATDLIEHLREISDLSIGVAAHPEGHPRSPDLATDRRYLAEKLRMSDFATTQFFFDI
EHYLSLVNDLADLGVTKPVVPGIMPVTNIGQVERMAELSGAAFPSWLRERLESGKTPEDV
RRIGVDAATELCAALLEAGAPGLHFYTMNKSTATRDIYTQLGLPVA
>A0A1L6KNP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter haemolyticus|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDADIKRFIEKVQAGANAGITQFFFNPDAYFYFI
ERLEKAGVSIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLSAYGDDSASIKAFGHE
VILKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1A9KJ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas citronellolis|TrEMBL
MTTSDRRFSFEFFPAKTEAGHEKLLATARQLAGYKPDFFSCTYGAGGSTRDRTLVTVLQL
DGEVNVPTAPHLSCVGDTKAELRALLAHYKDAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRAETGDHFHIEVAAYPEVHPQARNSEHDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAQKLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIASIQSF
GEQVITEMCERLLDGGAPGLHFYTLNQADPSLALWKNLKLPR
>A0A3B8IH77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagales bacterium|TrEMBL
MKVTDHIKNAKDTLFSFEILPPKKGESIETLFGHIDPLMEFKPPFIDVTYHREEFVYKTR
EGGLLERKTVRKRPGTVGICAAIKHRYDVDPVPHIICGGFNMEETENALIDLNFLGIDNL
LALRGDAMKSEATFVPDEGGHSYASQLIEQIQGMNQGHYLDEELQNAVPTDFCIGVAGYP
EKHFEAPNLNIDLKYLKKKVELGAEYIVTQMFFDNQKYFEFVDKCREAGIDIPIIPGLKP
LTTLRHLQMLPSVFHLDLPDALADEVANCKDNKGAREVGVEWTIHQSKELMEKGVPVLHY
YSMGKSENVYRIAKALF
>A0A352SR29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MASTIEMISKAATDWSIEVTPTGATKIESFRDCLPPGTTVNVTFLPGTDPAETIAVAERL
HNDGMRPVPHLAARSLRDADQLDELLTAFTSRCGVDEVLCIGGGVDKPVGTFDATIQVLE
AGLIQKHGIRSVGVAGHPEGSPDISDEEVAEALAAKNALAARDGLNLYIETQFCFEADIV
LDWERRVRAAGNTLPIRIGIPGPATIKTLFRFAQISGIGPSMRFIAKQAKNVAKLMTVQS
PHMLIAGLAEGMAADDACLIRHFHYYPFGGFARTAAYAGAIAGGNIELLPKGGFDVIAN
>A0A5B3G2X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes shahii|TrEMBL
MNVVEIINEAIASGRTRFAFELLPPLKGDGMQKIFAAVEPLMALDPAYVNITFHREGIKE
TEREDGSVEWHVVRRRPGTVGISAAIQNRYGVEVVPHLICGGLSKYDIEDTLIDMDFLGL
HNVLALRGDKSQNEKRFMPHPQGHAHAVDLVRQIADMNRGKFIDGEVEECHHSKFSIGVA
GYPEVHAEARDITSDIARLRDKVDAGAEYVITQMFFDNAKYFDFVRRCREAGITVPIIPG
IKPLSTLRHLEILPETFGVKLPEELVREVKAHPDGVREVGTEWAIAQSRELMAAGVPVLH
YYTMSRTTNIQKIVKAVF
>A0A3B9YTH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTLKVSFEFFPPKTADMEETLWRSIRRLAPLNPSFVSVTYGAGGSTRERTHATVKRIAEE
TQLKPAAHLTCVGATRADVDAVVRDYWEAGVRHIVALRGDMPDMGAYKVTPGGYATTPQL
IQGIRAIGDFEISVSCYPEKHPESASLDADLHLLEEKIAAGATRAITQFVYDTDALLRFV
ERAARRGIRVPIVPGLMPATNFKGVMRMAQRSGASVPLWLRDRFEGLDDDLETRKLIAAT
VAAEQVERLRREGLTQFHFYTLNQADLTFAICRLLGIRAQSPGSAAP
>A0A7Y1TE56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MKRFREAIKQQDFVITAALPLTPASTAAQISAAVETLAPFVDAIQVADDRYAVGHMSPLA
AASIVMQEGLDAIPHMSCRDCNRLALQADILAAAALGITTLVLLRGEKFTDVPALRAKGV
FHVSETQLIQMATLVGGESGLVSTPGFHIGSVVTAFRPEKTWEAKRIQEKIDAGTKFLQT
QPCLNIGLIRAYMQSLVERRVMHRASVIVEVPLLTSRQDARQLKKNYKGATIPKPAIMRI
MQAADTVAEGIKICAEMIADLKALPGVAGVNIQYAGDAQNVVSAIRQSQTARPPGHG
>A0A537TUF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTARQPASRLEALLRARQFAITAEITPPVSCEADDLLRKALPLAGLADAVNVTDGAGARA
HLSAPIAACLLARAGIEPVLQFTCRDRNRLALEADLMGAAACSVRNVLCLTGDDPRAGDQ
PQTKPVFDVDSVALTAIARELRDKGELPSGRKVAGHAAFFLGAADVPIDPPPSWRPDKLA
AKAAAGAEFAQTQFCMDTGVVRRYSAQLAKHAGTRDLFLLIGVAPLRSARSARWMRERLY
GTIIPEAFIERLERATDAAAEGERIAVELIEELAAIPGVAGVHLMAPANEDALPRVIAEA
RKRLPSRQH
>A0A3V7KSF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Pomona|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J3E7Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aythya fuligula|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFIK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYISGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A7X1CGA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDTICKHFNGVYIITPFLRYDLSIE
LTKYVQGKQEVAEQIISQN
>A0A1T1ZV27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKITSILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYNNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A222YE79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc mesenteroides|TrEMBL
MTRITDIYKKKSAPVLSFEIFPPKTEDGLHALYKTLQEVNPKETGVDYISVTYGAGGGSN
HKRTKEIAEYIERNCGITALHNLTGINQTPSSLKGNLEKISVAGVENIFALRGDTPTKDY
VNEYYPFAKDLIKEIKKDGRFDIGAAIYPEGHVDNPTTGISVTGVKEKVISGTEFLISQL
FFDNGVFYNMQEALKENYIKVPVSAGILPIISRAQVERITYMIGSSLPARLAKIVHKYED
QPEALQQAGIEYALEQIHDLLDHGVDGIHLYAMNQPNVLKIMLPEINRHIQSKILTL
>A0A5R1C4B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus epidermidis|TrEMBL
MSHLLNQLKSNVLVADGAIGTIFYSEGLDTCPESYNLTHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKSFGLEHKVKEIHQAAVQIAKHAANEDTIILGTVGGFRGVRQEDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELTRIVTATRQKYDIPIIAQLTASNTNYLVDG
TEINAALKYVVECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDIAQELINEGVRLIGGCCGTTPEHIRYIKSAVKHLKPVKDKKVIPINKAS
SQKQTRVLKQNLTSKVKNGPTVIVELDTPKHLDTDTFFDNVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQRYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGINTDGDALKKHTNFNIAGAFDPNVRKLDGAIKR
LEKKVASGMSYFITQPVYSKEKIIQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSDDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A5X9Y955|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Johannesburg|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5C8EFV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira aalborgi|TrEMBL
MNSVENFINKLENEKEFTFTLEVTPQAKSDLGYLVEKIKSSNIEKYIDAFIIPDSPFANL
KISPILSSLQLSQRLKTEKPFIITQTMRDKNSIALQNDLIGANYFDIRMVLALTGDPVVN
GNQKQAKGVFEGNSELLIRIIKNLNEGKSAGNFIFKEPLKKIYPFCSINSYSKNDEMLKV
RLSKKTASGVKAIFTQPIYEVETLKKFLNWIDEMPLKEMKLKEKPILFPGFFPVLSYKTA
YFIYYKLPGAYIPEEWLNKLKDASEKSAEEEKKVAFELSSNLFKDMLSVCKKMHIMSMNN
YDFVADLLKHI
>A0A450TR82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. FM|TrEMBL
MNIRRSDPQVFSFEFFPPKTPNGQNNLRTTRQQLAGLHPHFFSVTFGAGGSTQSGTLETV
IETQRETGIQTAPHISCIGSTREKIRQILDSYLDAGIRRLVALRGDLPAGMTEAGEFRYA
NELVEFIRAETADAFHIEVAAYPEVHPEAPSAKADLENFKRKVQAGANSAITQYFYDVDA
YLGFVENCQRIGVQVPIIPGIMPITNYASLANFSQRCGAKIPRPLAERLEGFGDDLAGLQ
AYGIDVVTELCRRLLEAGAPGLHFYALNRAEPSVTIWKNLDLPS
>A0A150NPL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADFIQNDLEIPTIAHLPAIYL
TKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGAC
YPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYDFQDKCTLAGIDVPIHAGI
MPILNRNQALRLLETCENIHLPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVA
GVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1I0C029|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas graminis|TrEMBL
MSQDRSYSFEFFPTKTDAGHEKLLATARTLASYNPSFFSCTYGAGGSTRDRTINTVLQLE
KEVHIPAAPHLSCVGDSKADLRSLLTQYRQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFH
FVERVQKMGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTASIQAFG
EQVITEMCERLLHGGAPGLHFYTLNQAEPSLAVWNNLKLSA
>A0A1S9ZDV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDMVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2N7V7L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. juglandis|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A7D5W6Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus mirabilis|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTQEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHAIIKDIKERTGLEAAPHLTCIDACREELQHIAQDYWQSGIRHIVALRGD
LPDNSQKPDMYAVDLVRLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKKKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMFD
GLDNDPETRALVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPQLAKV
>A0A7Y0DDC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycicoccus sp|TrEMBL
MARGTSSILPQPEHLSRSIPRLLAEVGTSYSFEFFPPKDDAGERTLWEAIRHLERIRPTF
VSVTYGAGGSTRDRTVRLTSRIARETTLTPMAHLTCVGSTVAELRQVVGEYASAGVRNVL
ALRGDPPGGLGTPWPPHPDGLNHADELVALVRSLGTFTVGVAAFPDRHPESASFDQDADV
LVRKADAGAEFAVTQFVFDPDSYVRLRDRVVARGRDLPIIPGLMPVTSFGQVRRMAELSG
TPLPAVVVSRLEAVADDPAAIHEVGVQIATELAQRLLAEGAPGLHFYTMNKSPATLEVFA
NLRG
>A0A497BGC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MIAGSNLEKVLRAGHFAVTGELGPPTNADKSIIDEKAEHLRGVVDAVNITDNQTAVVRMS
SIAVAAMLIEKGLEPVVQMTARDRNRIAIQSDLLGAWALGAKNLLCLTGDHQIFGNHPEA
KGVFDMDSIQMLAMMRDMHEKGIIQSGDDIDVPPTFFLGAAANPFAPPYEYRPYRLAKKI
QAGAKFIQTQCIYNMPRFKEYMQRAGDMGLLDNVYVMGGVTPLKNVGMAKYMAKSVPGLD
VPEEYIDRMRGATSGIPKENKKARRQALREEGIAICVETIQQLQEIPGMHGVHIMAIEWE
SAVPIIVEKAGLFPRPSV
>A0A536A4A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARITDLLAAGRTFSFEFFPPKDSEEQAVLTRTISELQPLKPSFVSVTYRGGRVSRERTT
RVVIDLLRTTELTPMPHLTCVAHPRFELGEIIGGFRAAGLENLLALGGDPLPAEESYKEL
EYASQLVELGRWLGFESIGVAAHPAGHPRSPDLKSDREHLAFKMNEADFAITQFFFKLEE
YERLRDEMAALGIRKPIIAGIMPITSLVSVQRMAQLSGYAVPDDIVRRIEAGGDDRAEIR
KRGIEVATELCRELLDAGVPGLHFYTLNFSKATREIYDNLGLVKT
>A0A496ZIY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTESVLEKVLASGNLAVTSECGPPRGAVPEKVKEKAEMLRGYVDAVNITDNQTAMVRMS
SFAACVIVRQMGLHPILQVVTRDRNRLAIQSDILGAYSHEIDNMLCLSGDHPHFGDHPEA
MNVHDIDSIQFVQMVKTMRDQGKFQGGGDILNPPKMFIGAAANPFADPFELRVARLAKKV
KAGADFVQTQCIYNLDKFEQWMQGVRDRGLHEKVYILAGVTPMKSAGMARYMKNKVPGMD
VPDEVVKRMAGVPKEKQADEGIKICVETIQRLKEVEGVSGFHIMAIEWEQKVHEITEKAG
LYPRPVV
>A0A661J2C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNTESRLEKVLRAGHFAVTSECGPPRGADPEAIRRKGELLKGVVDAVNVTDCQTSVVRMS
SLSSCLILKEMGFDPILQMVTRDRNRIAIQSDILGAAALGINNILCLSGDHQRFGDHPQA
KNVYDLDSIQLIMTVKKMRDEGKFLSGEELTKPPRLFIGAAANPFADPFEIRALRLAKKV
AAGAQFIQTQCIYNLKRFEEWMKQVVDMGLHEKVYILAGVTPMKSVGMARYMQKMVPGMD
VPEEIITRLKGVPKEKQPEEGIKICIEQIERLKEMEGIRGVHIMAIEWEEKVREIAEGAG
LLPRPDV
>A0A535E2G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIAEMLARGRPTVSFEFMAPRDENEVAMVEKTIAALAGHAPDWVSVTYRKATGKKTLEL
VTRIKRQYHIEAMAHLTCANTADETRPILNWMEREGVANVLALRGDPPGPGQAFVPADPQ
FQHGSDLVAFLRRSGYRFGIGAACSAEKHPESPDQAYEFRYMQMKVDSGADFLITQLFFD
NRFYFDLVRRAKEAGITIPIVPGLMPVPSRRSLAFMAAMTGATLQPDLARAIEEAPDDDA
VRALGVRHCIEQCVELLEAGVPGVHFYTFNRARAPMEILASLRGQQLLTA
>A0A6M4XED5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces asoensis|TrEMBL
MTPGRPRPAAGARGARGTGVREQAPAPRHLPQPAAPQPDRPGGARPPATTFSFEFFPPKT
AAGEQTLWKAIRRIEPLRPDFVSVTYGAGGSSRDRTVAVTRRIAAETTLRPVAHLTAVGH
PVAELRHIIGRYADAGIRDVLVLRGDPPGDPKGAWTAHPQGFAYASQLVELVRSLGDFRI
GVAAFPERHPRSRDWESDIRHFVAKCRAGADYAITQMFFHVEDYLRLRDRVAAAGCDIPI
IPEIMPATDHRQIARFAELCDAAFPEDLAARLHAARDDPRDAHRIGVEYATAMAERLLAE
GAPGLHYITLNKSTAALDIHRNVLSSPSARILHAC
>A0A2N5UTG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia coronata f. sp. avenae|TrEMBL
MKISQKLAAAESENRISWSFEYFPPKTDNGLTNLYDRIYRMSQLGPIFIDITWGAGGSTS
NLTTEFVKTAHEQFGLETCMHLTCTNMPREKIDNALKEAYEFGCENILALRGDPPKGSSE
WTATEGGFEHAIDLVRHIRAGYGDHFDIAVAGFPEGHMQSNLTKEEEMRYLKEKIDAGAN
FIFTQMFYDVDVFIGWVKELRAAGITVPVIPGLMPIQSWAQFKRVTTFHKTIVPQYFLDK
LEPIQADDQAVREAGTKLVADMCRKILNSDLGIRILHFYTMNLERGTKMILDELNLNPSR
DITNPLPWKMSLLGKRRSESIRPIFWANRAKSYLSRTETWDEFPNGRWGDSRSPAYGELD
GYGININSATMESLKTLTKFPVCLEDLARIFANYCGARFPGESPVKSLPWSDIPLSEETN
KIEDVLVKINKRGFLTINSQPAVDGVKSSDPVHGWGPRGGYVYQKAYLEFFCCPEKFQSL
TERLERDPDVTYYAVTKTGDLVTNNTRAGPNAVTWGVFPGKEIVQPTIVELVSFIAWKDE
AFELGHQWAELYHDIAPESARFLHEIMDSWFLVNIVNNDFRKSNDDSDNSALFQFFGPEP
IIVHDDPDHTPTATSNGVHHPNGSSKTNGASLNGLNGDLKHLAI
>A0A4Y7UH83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium circumlabens|TrEMBL
MKVTEHIENAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
IMALRGDAMKDEQYFIPKAGGNDYAIDLVKQISLLNQGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNTKYFEFVAKAREMGITVPIIPGIK
PIAVKRHLQILPQIFRIDLPEDLIHEVDKCKDNAAIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASRIF
>A0A2E7Q5L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTTPRVSFEVFPPRSVDAAFKLWDTAQALAPLAPRFFSVTYGAGGSTRDLTQDSAHVLRR
TSGLPVAAHLTCVGASREETLDVARGFTEAGVTDIVALRGDPADGADRFTAHPQGFANSC
ELIEALADMNQFTIRVGAYPDSHPDAADEAANIEWLKRKFDAGADEAITQFFFEAETFLR
FRDACEKAGIDKPITPGIMPVVNWKSARSFAERCGALIPDWVHQSFDAAIRDDRHDLLAT
ALCTELCSDLIDEGVDTLHFYTLNRAELTRNVCRALGVTPQVALSDVA
>A0A0L9Y4B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MNIKNLFKDKKVVFSFEIFPPKTTSSIQTIYDTLDDLKGLNPDYMSVTYGAGGSVKNNNT
IELSSLIKNKYGIEPVSHLTCINLTKKDVEYYLREFEKNNIENILALRGDVPIGSKITGE
LNHANELIKYISDNGNFNIAAACYPEGHIEHKGLYREIESMKRKEEAGVSYFISQLFFDN
NLYYNFQDEVRAANINLPIEAGIMPVTNKRQIERILSLSGASLPDKFKRIMERYEHNPEA
LRDAGIAYAVEQIVDLISTGVDGIHLYIMNNPYVAKRISQSIESILLTVNQI
>A0A1S3WNT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erinaceus europaeus|TrEMBL
MVNEPRGLGGPQPHSEGSSSGGESSRDSSRCSTPGLDPERHERLREKMRRRMGSGDKWFS
LEFFPPRTAHGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETVLHMTCCQQSRETITGHLHKAKQLGLKNILALRGDPLGDQWEEAEGGFNYAVDLVKH
IRSEFGDYFDICVAGYPKGHPDAGSLEEDLRHLREKVSAGADFVISQLFFEADTFFHFLK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGVEL
AVSLCRELLASGLVPGLHFYTLNREVATTEVLKRLGMWNEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELRDYYLFYLKSKSPREELLKMW
GEELASETSVFEVFAHYLSGEPNQQGHRVTCLPWNDEPLAAETSLLKEELLRVNRQGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYDLRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWMEQWGKLYEE
GSPSRKVIQHIQDNYFLVNLVDNEFPLDNCLWQVVEDTFELLHGPVPSKREPAAP
>A0A8E4EIY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas euroxanthea|TrEMBL
MTTNARQDRLTHPHTPRLASTITDAYSLEVSATAIAGLSAAAPAIMRGATIAIPYLPNQD
DAARLAAACMVRKLGFAPMPHLSARRIGSLDALHAFVRRAVDEAGVERCLVIAGDPPSPI
GPFPDSVSLIDTGVFERCGIRTIAVAGHPEGHPGMPASERWDVLKRKCRSIAERGMAPLI
VTQFAFDADLVLTWLHALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACTAMLSKYG
ISLGKLLGTAGPDRFVDRLATGLTGAHGEVSLHFFPFGGIAQTVAWVEQYRARTAPHRAD
>A0A6A7JR42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter hepaticus|TrEMBL
MCSFSFEIFPPRKDENIKNLDAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEK
YKIPSIVHLPCIHSSKEKITQILQQCKDRQLNKILALRGDVCNNLEKSKDFSYASDLISF
IQKYKDFEIYAACYPEKHNESKNFIEDIHYLKNKVDLGTNKLITQLFYDNDFFYTFKQNC
ALANINIPIYAGIMPITNKRQVLKITQLCGSKIPAKFTKILEKYENNALALEDAGIAYAI
DQIIDLITSGVDGIHLYTMNKSRAAIKIYEAIKYLIKVS
>A9U4S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Physcomitrium patens|TrEMBL
MKVIDKINNGLAGGNVVFSFEFFPPKTEEGVENLFDRMDRMVMHQPAFCDITWGAGGSTS
AVTLDIANKMQNMICVETMMHLTCTNMLVETLDGALDSVKSNGIQNILALRGDPPHGQDK
FVTIEGGFSCALDLVRHIRAKYGDYFGITVAGYPEAHPEVIGEDGVASEEAYQKDLAYLK
EKCDAGGEVIITQLFYDTDIFLKFVNDCRQIGIKVPIVPGIMPIQNYKGFLRMTTLCKTK
VPAEIMAALEPIKDNDEAVRAYGIHLGTEMCKKILAHDIRTLHLYSLNLEKSVLGILQNL
GLIDFSRVSRPLPWRPPTNSKRTKEDVRPIFWANRPRSYISRTTSWDDFPRGRWGDTANP
AYGSFSDHQFTRKKTRSKKLQKEWAVPLNSSEDVNAIFAKYCQGTLSTHPWSELEGLQPE
TVQINEKLVALNQGGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSPEKLQ
AVIEKAKTSPSLTYIAVNAKGETKSNVGPTSVNAVTWGVFPAKEVIQPTVVDPVSFMVWK
DEAFQAWDQEWASLYPEDDASRKILSEIKSSYFLVSMVDNDYINGDLFSVFA
>A0A718A403|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Typhi str. CT18|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A315T4I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium animalis subsp. lactis|TrEMBL
MHTPMFSLEVFPPKRTSPVGTIYDTLDGLNDMKPDFISVTYGTGKSADRTATARIAHTIH
SEYGIDAVAHLTAQYLTARDVDEALAMFDEAKVSGVLALRGDRNSEREPAGVFTHASDLV
CYIRERRPNLKIYGACYPEKHPQAATLDEDVANLKAKVDAGASHLISQLFYDDDDFIAFL
GKARAAGIDVPIEAGIMPVTNAKSVRRMTNMCSSRVPRKLERMLEKWGDDPRTLREAGII
YASEQISDLVAQGVDGVHLYTMNHPSVSRRIWQNVGNLFEKA
>A0A2A5HB63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVIEHINKAKKTLFSFEILPPLKGKGIQSIYDSIDPLIDFNPSFINVTYHREEFIYKKR
EKGYLEKIAIKKRPGTVGICAAIVNKYKVDAVPHIICGGFTKEETENALIDLDFLGIDNV
LALRGDPIKTEPAFIPEKEGHQYAVNLVKQIVGLNKGIYMDEDLQNASPTDFCIGVAGYP
EKHFESPNIKSDLKHLKQKVDSGAEYIVTQLFYDTEKFIDFVNLCRKNDISVPIIPGIKP
ISNKNQLISLSKFFHIDLPDDLVDAVEKCKDDEAVKQVGIEWAIDQSKKLVKFGVPCIHY
YTMGKSVAVKEIAKAIY
>A0A173U2F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerostipes hadrus|TrEMBL
MKISEILKNKSTISFEVFPPKNKEGDISSIYSTIEGLAKLSPDFISVTYGAGGSTKGKTV
EIASVIKHEYGIESVAHLSCISSTKEDIKYECERLKEAGIDNILALRGDYPADATNFDPE
NLEFHYASELNEFIGEHFKGQFCLSGACYPETHQEADGFKKDLEALKKKVDAGAEYLVTQ
IFFDNDYYYRLVREARKIGITVPILAGIMPITNAKSLIRTTKMCGCTIPYQLSTMIEAHY
DNPEAMKEIGINYAAQQIIDLITNGVDGIHIYTMNRAETAQRVFDSIPAVLKELN
>A0A2T8X4W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Gaminara|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A370FZ09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconacetobacter liquefaciens|TrEMBL
MNNTVEHRPAQALPGAFPPHALDMPAPALSFEFVPPRTDAQAHRLWQCIRRLAPLSPRFV
SVTCGAGGSTQASTRATVLRLKRETALVPAAHLTCVGASREDIDEIARSYWEAGVRHIVA
LRGDPPAGAADYTPHPGGYTHASDLVAGLRRIADFEISVAAYPETHPAAPSPDADLDNLK
RKLDAGATRAITQYFFDAETYLRFLDRCMAAGITAPIVPGIMPVSNYDQVARFSALCGVT
VPAWLTHLFEETSKNPELRRIVASVVAVEQVRALQANGINAFHLSTLNHADLTFAIAHIL
GLRPTEPSAPTESLAEKGV
>A0A0M0Q2B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J6U7D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARIGDLLAAGRTFSFEFSPPKTTAGSMSLGRTIAELESLSPSFVSCTYGAGGSTRENTR
DTVLWIERETNIPAMAHLTCVGHTRHEIEDIIATYTAAGIQNVLALAGDPPKDPADARPS
DYMYALDLVEHLCEIADLSIGVAAHPEGHPRSPDLATDRRLLAEKLRVVDFATTQFFFDI
DHYLSLVNDLADLGVTKPVVPGIMPCTNIAQVERMAELSGAAFPQWLRERLESGTSPEDV
RRIGVEAATELCAQLLDAGAPGLHFYTLNKSTATREIYAQLGLPVA
>A0A6J6A0U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MAHISDLLAAGRTCSFEFFPPKTDDAARALEQTIAELAPLDPSFISVTYGAGGSTRERTR
DVVINIERNLGITAMAHLTCVGHTRAQLDSLLDEYKAAGVSNILALAGDPIVDDNGVVAE
SEFEFAMELVELIKEKGDFSIGVAAHPEGHPRSEDLYSDRRRLADKLNVADFAITQFFFE
AEPYMRLVEGLSAFGCEKPVLPGIMPVTNAAQVVRFAQLAGAEFPPHLAARFDAIAEDGD
AVRALGVELASELCQRLLDEGAPGLHFYTLNRSTATREIAANLGLGDASSAGV
>A0A504ZA98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAKADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1C5XB69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Eubacterium sp|TrEMBL
MNTMQTNPQDILKTLSLSFEVFPPKKWEDFPGLYETLDELKGLHPEFISCTYGAGGSNSK
KTAEIASHIENELGIRSIAHLTCAALTEDKLLSTIENFKNAGIHSVLALRGDKPFDMSEE
DFANRQYKHPSEIIPILKKAGFRVAAACYPEKHYEAPSMEEDLHWLKHKVEQGADALISQ
LFFDNDAFYRFMDAADQKGITVPVHAGIMPITSAKMINTTINLSGASIPKTLSDLIATYG
ENPSDMRKAGIEYAARQINDLAEQGMHYVHIYTMNHSETAKEICALIK
>Q83SU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhi|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5F2C382|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira selangorensis|TrEMBL
MKKILEIYKTAKLPVYSFEFFPPKTPEGEVKLFEAVGELSKVDPGYITVTYGAGGSTREK
TIRITSELAKKFSLPAAAHFTCVGGNKDEIRVILKQIRESGIENLMALRGDPPKGEEAFK
KVEGGFGYASELISFIKEEGFDFCMGAACYPEKHPEAASLESDVDNLKRKVDSGASYLVS
QLFFKNSNFESFLNLIRKKGINVPVIPGIMPITSFTQIERFKAMAACEFPEKLVSDLEEV
KDQPQEFYKRSVNFSVNQCRELVKMGAPGIHLYTLNQSPASLDIVRELKN
>A0A6L9H6V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKIRDILGRGKPTLSFEVFPPKEESNYESVERAAFSIAELKPAFMSVTYGAGGGTSRYTI
GIASDLQRRCKVNALAHLTCVSSTRGEVRERLLQMQEAGIENVLALRGDIPKGGPTASDY
RYASELIRDIKELAPDICIGAACYPEGHVESENKTADIVHLKEKVEAGCDFVTTQMFFDN
HLLYNYLYRIREQGITVPVVAGIMPVTNVKQIARIVGMSGTCLPPRFKAVLDRFGDRPAA
MKQAGIAYATEQIIDLIANHVNAVHVYSMNKPDVAGKIRESLSEIL
>A0A817GHT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood2|TrEMBL
MTLTHTEKNTASNHHDAHENGIGAENMSNSSHHFVDLKRSESEHACLAARGNSLQPVKYV
SLTEKIEKKIANNDRWYSLEFFPPRTTNGAVNLIGCLERMATGDPLFCDITWHTAGDPAG
TKETSTMMIANTMLNYCNIDTMLHITCYGAKKATMIEYLSKAKNFGIRNLLALGGDPPVG
ETWDPEKNDFRYASDLVKFIREHFGDYFVICVAGYPKGHPDSKNYEEDLGYLKEKVDCGA
DFIITQLFFQAETFLKFQSDCRAVGITCPILPGIFPIQAYASFKNIVRLTKLDVPDAIQT
HMESIKDNDQAIRDFGVQTCVDLCKALLDSGKVHGLHFYTLNREYATTEILKQLGFGFED
PPLRALPWKKTSRNHVRSKEDVRPIFWSTRPKSYIHRTSNWNEFPNGRWGISSAPSFGVL
TDYHLFYLKIDAAHNELLDEWGHELTSEQDVWKMFACYIGGEKNSSDKIVRHFPWKDEDM
SLETNLIHNELVEYNRKGILTINSQPAVNGKPSTDPIFGWGEKNGYIYQKAYLEFFTSAN
NIPALRAVLKDFPGVNYHFVNKSGEVNETNTDDEQPIALTWGVFPGKEIIQPTVVDPDEA
FNLWMERWGKLYEAGSRSYSIIEQISNTYFLVNLVDNDYPQGSCLWAVLDAMFEYQQKTN
QDTNS
>A0A3V7VYI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Paratyphi B|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1I0FZN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster lavalensis|TrEMBL
MKIRDILAAGNPTLSFEVFPPKTVDAYEPVERAACEIAKLKPAFMSVTYGAGGGTSRYTV
DIADTIKGYGVTPLAHLTCVSSTREKVHQVLDELKSRGIENVLALRGDLPADGETPREYR
YASQLIREIKESGDFCIGAACYPEGHVESANKSVDMDYLKEKVEAGCDFVTTQMFFDNSI
LYSYLYRIREKGITVPVIAGIMPVTNAKQISRITGMSGTYLPARFKAIVDRFGDNPAAMK
QAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAARIRENLSEIL
>A0A815A277|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adineta steineri|TrEMBL
MYNNEIDPDAGHHPHVFKRAESDSGLQAKGCCLQTVKYVSLTEKIEKRIASNDRWYSLEF
FPPRTPSGAANLIGCFDRMAVGQPLFCDITWHPAGDPASNKETSSMMIANTMLNYCGIDT
MLHITCYGAKKEHMLEYLYKAKEFGIRSLLALRGDPPVGEEWDPKKSDFRYGVDLVKFIR
QHFGDYFVICVAGYPQGHPDSTSYEDDLGYLKEKIDCGADFIITQLFFKPETFIKFESDC
RAIGITCPIIPGIFPIQGYASLRNIVRLAKLDVPKEILACIEPIKENDEAIRNFGVQTCL
DLCSALLDTGKVHGLHFYTLNREFATIEVLKKLGLWLEEHPLRALPWKKTSNSHTRSKEN
VRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGMLTDYHLFYMKIDATRDELLDEW
GRELTCEEDVWRMFACYIGGEKNTSNKVVRHFPWTDEELSLETTLIQNNLIEFNRRGILT
INSQPAVNGKPSSDPIVGWGTSNGYVYQKAYLEFFTSADNIPALRAVLKNFPSVNYHFVN
KSGESNETNTVDEQPIAVTWGVFTGREIVQPTVVDPVSFMIWKDEAFSLWTERWGKLYEP
ESRSHAIIEQIANTYFLVNLVDNDYVEGSCLWTILDSMFEYQKVSKKDGNI
>A0A414EA74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides ovatus|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A450W252|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. LPFa|TrEMBL
MNPSDSNPLVFSFEFFPPKTSQGHDKLRATWRRLSQLDPNFFSVTFGAGGSTQVGTVETV
LEIHRDSGINAAPHLSCIGSSRVKIREILAHYLSNGIRRIVALRGDFPPDMAEPGEFRHA
NELVEFIRAEVGDKLHIEVAAYPEFHPTAPSASADLENFKRKVEAGANSAITQYFYNKDA
YLRFVDNCQRIGVDIPIVPGIMPITNYVSLAGFSERCGAEIPRWLRWRLQEFGDDMKALR
AFGTDVVTELCQELLSAGAPGLHFYVLNRAEPIMTIWKNLDLSNRQGPR
>A0A6N3BSY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella parvula|TrEMBL
MTLREKHQQGQFTITVELDPPKSSSAEKTFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDSPTNFYIGATGNPGAPDLEIERQKLAAKIQNGA
HFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
MEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A6G3X1M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7499|TrEMBL
MALGTASIRSDHARTVRDMLAAGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWDADVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLERIGSLTNAAF
PPALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSPQA
>A0A2D8JET0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MKSLVQDNRVHVFDGAMGTLLYNRGVFVNVCYDELNLSRPELVRGIHEEYINAGAEILET
NTFGANPVKLSSFGLADRTEEINEQAARLAVEASSKAEVSELSTGNLPEHPSGRTVAVAG
ALGPLGIRIEPWGPTSLGEAEAYFARQVDGLLKGGVDGFVLETFSDISELQCALRAIRVA
CELPVIAQMTVGPDGKTSLGTEPAXLAQAMEDSGADVXGLNCSVGPXVMLDALEXMAEXT
QLPLXAQPNAGLPRNVRDRKIYLASPDYMAXYARRMXDXGVRFVGGCCGTTPXHTXRMRD
SVAALQPKHPXVTIRDRXNXSXSXTNPVPLEXXSAWGRKLARGEXXASVEIIPPHSWDAS
AVTSPARELKVSGVDAVSIVESPRSRSRMGALSAALIVEREVGIETIVHYTCRDKNMLGM
ISDLLGAAAAGIRNVLVVSGDPPVTGPYPDTTVVFDIDSIGLTNVVQGLNQGIDPGGNTI
GAPTEFVQGVAINHGAVDQERERSRFEYKIEAGANFATTQPVFSPEALEKFLDATTPEIP
IIAGIWPLTTLRNAEFLANEVPGVHVPTEVVDRMRRAQLSGGEAALEEGIAIALEMINAT
QGFVQGFHLTAPNRXVQVALKVLRESGVLETA
>A0A7C8DH75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MKPISIELVPRSVESLTEDLRVLRDQFPSIEMVNIPDLLRFDVRSWDACQLAQMTQPRTI
PHIRAMDFSQKNAEGLCAKLTERGLDEILVVRGDPPQDMSRRVHPTTAADLIRSIKQIAP
NIRCHAALDPYRAGMQTELDGVREKLEAGAVGLFSQPLFDLRYMEIWRDQLPGVEVYWGL
SPVVRESTRRYWEVKNCAFFPGSFEPTLQWNRAFAQTCIDWARENDEGLYFMPIRVDIAA
YLEGLV
>A8IAY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlamydomonas reinhardtii|TrEMBL
MKLIHKVEEKMKKGETFFSFEFFPPRTEEGVENLFERLDRMVAYGPVFCDITWGAGGSTA
DVTLDIATRMQNLICVETMMHLTCTNMPEEKLESALHEVKKMGVQNILALRGDPPKVRVG
ACVCVTSAVHQDESQHGDYFGICVAGYPEAHPDGIVDDPEQMKKNYWADIAYLKQKVDAG
GDMIVTQLFYDVDVFLQFVKDCRSVGITCPILPGIMPIMTYGGFKRMTGFCKTKVPAEIS
DALEAIKDNDEAVKAYGIDLGVRMCRQLLASGEVPGVHMYTLNLEKSAVAILEQLGLVDT
SRVQRPLPWRHVPAGTARAVEQVRPVFWSNRPKAYVKRTQDWDSYPAGRWGNTRSPAYGA
LSDHQFMRRHSTGEARREKARAAWGAAPASVDDVKQVFVKYIKGEVSLLPWAELDGGLTA
EAAAIREPLAALNANGYLTINSQPRVNGVASDDAVHGWGGPGGYVYGKAYVEFFCSPEAW
ATLRAKLDAAPSITYLATTAAGSPAGNMAPDAVNAVTWGVFPGKEVIQPTVVCAPSFAVW
KDEAFELWTSEWGALYEEGSAARDLLAGIKDSWVLVSVVDNDYVAGDLFGVLLG
>A0A6G3XP81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7499|TrEMBL
ATQQIAADSTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVRGDPPGDPMGEWVEH
PQGVKYAADLVRLIKESGDFCVG
>A0A4R6BBP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrococcus brunensis|TrEMBL
MTILDTLKKRILVGDGAMGTLLYAEGLDTCPEHYNLTHPDKVEAIHRLYVEAGADVIQTN
TYGANFEKLKAYGLEHRVKEIHQSAVAIAKRAAGPDTFVVGTVGGFRGIKKLELSLSAIL
YHTSFQIDTLVQEGVDAILFETYYDVEELLAVVEYARSFKIPIIAQLTAQDTCFLKDGTV
IQDALIRLEATGADIIGLNCHHGPHHMNQTYKHLALPEHAFLSCYPNASLLDIEDNMLKY
SDNAVYFSQVTRELVREGVRLIGGCCGTTPSHIRRIKDAVADLKPATSKNVIPFQRGAQS
VIQKKEPSLKELVEQRPTIIVELDTPKHLDKGQFFRGIEALEKAQVDAVTLADNSLACVR
MCNIAAASMIKHHYNIRPLVHIACRDKNIIGLQSSLMGLAALGISDVLAVTGDPSKVGNF
PGATSVFDVNSLGLAEIIRQFNRGIGADGSSLRKHTTFTVAGAFNANVSKLHASVQRLRK
KQEAGVDYFITQPIYDKNKIREIYNSARQLDTSIFIGIMPITSYKNALFLHNEVPGIKLP
EELIEAFRIVKDDRDKTQKLSLEICQELIDETLKYFNGIYLVTPFLKYELTVELAEYAQR
LTKKQGVVL
>A0A7C4YNA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MRIRDLYNSGKLVISFELFPPKDWQGLAELYEHFKELIKCKPSFITCTYGAGGSGGAKEA
QQRTYEVLKWIKKDYPQVPLVSHLTCVNATKEELKDYLTKVNELGVVGIVALRGDAPGKT
KQFIPYPGGFRYAVELVRMIKEEFPNLSVLVAGYPEKHPEAPTLEEDIKHLKEKVDAGGE
VVLTQLFYNNEDFYRFRDLCVKAGINVPIVPGILPVTNLSQVKRITSLCGAKINEMLLQR
LEKYPDDEEGQFLVGVYYATGQVEDLIKNGVPGIHFYVLNKSRSAQYICKALSL
>A0A2A9LWK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. JKS000303|TrEMBL
MSSLKQALNEGRFVCVLEIVPQQSPSRLAELGQIVQRGHLAGWPLLPAFADRVGLHSDLS
PLEGAGALGNPASSLLHFSGKDRERADLLRQMASMQARGLEQMLVLSGDRLPGHDPGQAP
VRYLESVSALQIARERCPDWLLGAALNPFKYREEEGGAQYLKAQKKLLAGADFLTLQLGF
DAAKHGEAQTWMRAQGRMKPMLACVMRLTDKRAAVLQAVPGVVITESMRELLSREQQVSH
AHASARSFERLALQIVGLRLMGYAGVHVSGVHTLDELLALEQAIAEQRDGMTSLTDWAAR
WHASWQMPGAPEVCFAPEIGAWEMGQSDVTATRRERLRYTLLSTIHGQVFDRAGWLGRAF
GWGVTRPIWKIGVAASALHAVERTVKRPLVGCDTCGRCRLQDTLYVCPETCPKGLANGPC
GGTRLNRCEFDDRECVHSVKYRIAKSVNQLPVLAQTLIPCIEAENRHRSSWPEWFEPEET
TPGR
>A0A828Z9X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus fusiformis ZB2|TrEMBL
MRRNNNDESLKPSFFMKEGFLLYRDIGREANFMGLLERLKTHVLTADGAIGTVLYGYGLE
YCHEEMNVQRPELIEKIHREYIAAGADIIQTNTYGANAIKLARYGLESRVQQFNEAAITI
AKRAAADGGQFVLGTIGGIRGIRKSDATLDEILATIEEQARVLLAGNPDGLLLETYYDLE
ELTATLKMLREKTKLPIIAQVSMHEPGVLQNGVSLNNALHELEVLGADIVGVNCRLGPHH
TIQAFEGVELPHKAFMSAYPNASLLDLEDGRVVYESEADYFGRAAVELRDQGVRLIGGCC
GTTPKHIAAAKKYLEELSPVQEKHAKPKKIEIVREAEPTKYEPLHEKVKRERSVIVELDT
PRHLEIDGFLEGAKQLYDAGADVVMMADNSLASPRISNIAMGALLKSSHGVRPLTHITCR
DRNLIGLQSHLMGLNALGIHDVLAVTGDPTKVGDFPGATSVYDVSSMELIQLIKQLNEGV
SFSGKPLRKKANFSVAAAFNPNVRVLERAVKRLENKIEHGADYFISQPVYTKEKIVEIYE
ATKHLQAPIYIGIMPVTSYKSAEFLHHEVPGIKLSEDALTRMKACGEDKERATLEGISIA
KELVEVATQYFNGIYLITPFLRYDVTLELMKYIEQLDEQKKGVSIHG
>A0A2A9LP19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. JKS000303|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLMPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDNLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTDLCRRLIDAGVPGLHFYTLNAASATRTICDRLAG
>A0A2A3E0M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3859|TrEMBL
MNARQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWQREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A1Q6PTY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea sp. 42_8|TrEMBL
MKISDILVEKTPHLSFEVFPPKTDAAYEGVLKATEAIAELKPSYMSVTYGAGGGTSKNTV
KIASHIKNKYGVTSLAHLTCVSSTKEEVHQVIDQLKTAGIENILALRGDIPKESEFPLPN
HYQYAYELIRDIKTQGDFCIGAACYPEGHVESEHKKDDIAHLKQKVDCGVDFLTTQMFFD
NNILYNFLYRAREKGVTVPVIPGIMPVTNASQVKRILSMSGTNLPERFKAIVDRFGDNPK
AMQQAGVAYATDQIIDLFANGINHVHVYSMNKPEVAAAIQANLSDILSK
>Q11GQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chelativorans sp. (strain BNC1)|TrEMBL
MTNYRFARRHEAAEKIRVSFEFFPPKSDEMAEKLWETVVRLAPLQPAFVSVTYGAGGSTR
ERTAHTVRRILQETELTPAAHLTCVDASREQVDGVISEFAAMGVKRFVALRGDPVEGAGA
AYRPHPDGYINGADLVGALARQGDFDISVSAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDVYDRYVERVRRAGIYVPIVPGILPVHNFTQVVRFASRCGAYVPPWLAERFH
GLENDPSTHQLVAAAVAAEQVLDLVERGVSDFHFYTMNRADLPFAICHMIGVRPAAQPSG
EVAVA
>A0A4Q5P1W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobiaceae bacterium|TrEMBL
MECEMTVTTPATPNLPNISFEFFPPKTEEMDRTLWDTIERLAPLAPSFVSVTYGAGGSTR
ERTHATIVRLLKETALTPAAHLTCVGAPRGEIDDVVARYYEAGVRHIVALRGDPSAGIGT
PYFAHPDGYQTSADLVASIRKRYPDIDVTVSAYPEKHPESLDFDADIDTLKAKVDAGATR
AITQVFFDNDLYFRYLDRVRARGIDVPVLPGIMPMHNFKQARNFVTRAGTTVPGWLADKF
DGLDDDTETRKLVAATVAAGQVQKLAKQGVNDFHFYTMNRADLVFAISHLLGFRPNAARK
AA
>A0A3M2EQD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MVEERRSGDSVRPFFSFEFFPPKSERGEIALYEAVERLKDLNPDFVSVTYGAGGSTRDKT
LEWTETIQKRYGIPAMAHLTCVGSSRGELHGLIEEIDRRGIRNILALRGDPPRGTGEFRE
APNGLRYAEDLVRLIRATGREFSVGVAGYPEKHPEAPDIETDIRHLKDKIAAGADFVLTQ
LFFENEHYFNFIEKLQYGAKKTKRGWVSGIPVIPGIMPVTKKNQLDRFVSMCGAFIPERL
RRIVDEAKDDREVEERGTAFAIEQVRGLLAGGAPGIHFYTLNKSRATVRILEAVKGETAA
G
>A0A0G3H8K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium testudinoris|TrEMBL
MNPTMPRHRAHSRFSASAPLDRFDERYDDAEAPHRSPQRTALSFEVMPPRRDADQETIAE
LLDTLESYNPDYVSVTSSRNSGWLEGTTDFISKITATTRMRTLAHLACTAGTREELGVWI
DRLMDAGVRGFLALRGDFAEGQHSLPAGYLPHANELVRLIRDIEGRQAARFGAGRLAIGV
AAYPSGHAESASVDEDLDVLLAKQRCGADFAITQLFFDAEDYLRFKERSELAGVRIPLIP
GIMPMTSVQRLRRMGQLSGLRVPDRLIRRLEAAGPESEYEVGLELTAELAQTVLGAGAGG
LHLYTFNRSDTTREMLDRIGLSAS
>A0A834GHV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhododendron simsii|TrEMBL
MKVIEKIREAESGGKVVFSFEFFPPKTEDGVDNLFDRMERMVAHNPTFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVDKIDHALHHIKSNGIQNVLALRGDPPHGQDK
FVQVQGGFACALDLVKHIRSTYGDYFGITVAGYPEAHPDVIQSDGGLATPEAYQSDLAYL
KRKVDAGADLIVTQLFYDTDLFLKFVNDCRQIGITCPIVPGIMPINNYRGFLRMTGFCKT
KIPSEITAALEPIKDNEEAVRAYGIHLGTEMCRKILANGIKTLHLYTLNMEKSALAILMN
LGLIEEAKILRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWEQYPQGRWGDSRN
ASYGALTDYQFVCGPSLILFDGIEIMLHLHMWEGGAEDVKLVFMRARTRDRKLHDEWAVP
LKDVEDIHERFLKYCLGNLRSSPWSELDGLQPETQIINEQLGSINSKGFLTINSQPSVNG
AKSDSPIVGWGGPDGYVYQKAYVEFFCSEEKLNTLVEKCKSFPFLTYMAVNKEGSWISNV
RSQSDVNAVTWGVFPAKEIIQPTVVDPTSFMVWKDEAFEIWSRGWAQLYPDGDPSRKLLE
QVQSSYFLVNLVENDYVNGDLFAVFRDF
>A0A6G7CEX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio ziniensis|TrEMBL
MGYTHAGHIDALNQNISELSNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLVSAPHLTCIDASREELINIADDYWANGIHNIVALRGDI
PPGGGKPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFAQASRFAAQNNVKVPSWMAKQFEG
LEDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPTR
>A0A841EQC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcicella rosea|TrEMBL
MTKITQYIEQAKGKTLFSIEIIPPVKGDSIQALMSNIEPLMEFKPPFIEVTYHREEYLEK
IVNGQIDRIPIRKRPGTVGICASLMNRFNVDAVPHVICGGFTKEETEDFLFDLHYLGIDN
VLVLRGDPVKGNPAFTPEKGGHAFASDLLQQVVSMNNGELLHEETQASPTNFCIGVAGYP
EKHFEAPNFNTDFNYLKKKVALGADYIVTQMFFDNQKYFDFVKKCREEGINVPIIPGLKP
LATKKQLTVLPRIFHLDMPEDLVTAVTNCKTDKDVKQVGIEWCIQQCKELMAFEAPILHF
YTMSKSESTKKIAEAIF
>A0A7J5VQF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MLVKDIFDRHKTTFSFEFFPPRPGIAEDAAADRILATIKNLMPLAPSYVSVTYGAGGSSR
HRTRDLVVRIKQETNITVVSHLTCVGSSKKEIHEILERYKEIGILNILALRGDPPKGVTD
FVQPENGFNHAVELVTYIKKHFPEMCVGVAGFPEGHPATPNRLLEIDHLKAKVDAGADYI
VTQLFFDNRVFYDYCERCELAGIRVPNIAGIMPVTTRKGLIRTAELAGGTNIPARLLKAV
FRAENDSYVEKVGIHWATEQIRDLIDHDVRGVQFFTLNSSTATQEIYTSLGVSNSKQLRE
>A0A7S0W7D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hemiselmis tepida|TrEMBL
STPNTLQFAKRMAAPAETPGGIAFREIIASKKPVVFDGAMGTTLYEQGVLHTRAFEECNL
TAPGKVKAVHAAFIANGANVIETNTFSANKLALHRYGLTNIAELNRVGVELAKEAAAEGG
KGTIVAGAVGPSGEGTGFIDDDKAAEIEGAFREQVEAMVAAGVDVIVLETFQYLAEIRLA
LSLVKKVFNGPVIASMAFTDEPAATNHYGPGKVAQLLKQWGADVIGVNCGGGWGRVGEGG
PAAIYDVAEEMVKAVGSGTPVVACPNAGHPKRVGHRNIYLATEEYFLVYAKRLFKSGVRM
VGGCCGTKPEHIASVASAARMFGGGDDITPAPEVPAQEATASKKKKTEAGVALPLIPLED
RTGLSAKVARIWQGRLQGGKGKGSPTGPEDFVVSVEVNPSPGLSTDKPIATATMLRKAGV
DVVNIADGPRATVRMSNTALAEVVQRELEMETIVHVCCRDRNILGLMSDLLGNYSRGLHN
LVVITGDPPKMGDFPKATAVFDMDSVGLLKMIHGLNTGLDPAGNQFAGQAKYFCATGAEP
GAVDYEREIRRLKEKIAAGADMVMTQPVYDPSVMRKFLDDVAAFPKPVPVLLGLCPLVSS
RNAEFLHNEVPGMSVPQNIRDRMAAVGGGPPGVAEGVAIARELLLQFQDEVVGCYVMPQL
GKYEAAVEVVRHLGYGEEGAADRRDAAGKK
>A0A849WFP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Brocadiae bacterium|TrEMBL
MNVRQIFQSSKTAVSFEFFPPKNENASRSLFETIKSLIQIQPAYVSVTYGAGGSTRHLTH
DLVVKIQQETNLTVVSHLTCVGSTKEEIHSILQKYHDSGIRNIMALRGDPPKGESLFTPV
QNGFNYAWELVAFIKKHFPDMGIGVAGFPEGHPESNNRLTEIANLKQKVDAGADYICTQL
FLDNRDFYDFCERCELAGIHVPIVAGIMPIVSLKSMNRMAELSARSRFPAKLLRLLYRAG
TEENVERAGLHWAAEQVRDLLDHKVRGIHFYTLNRSEQVHKICEALGINNSLQLQ
>N8VLJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 899|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQRNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHKIAGIVITPHMLRVLAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVET
KKELVPQLAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>U5LAE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus infantis NRRL B-14911|TrEMBL
MSLLDKMEKEIIIADGAMGTLLYSYGTDFCFEELNVSQPGHIQNIHQAYIDAGATLIQTN
TYAANYLKLQRYGLEDHVKEINSAAVTVARKAAGNHAFVAGTIGGNRGIKPHSISIEEIK
RSFREQLYCLLMEGVDAILLETYYDLKELETVLSIARKETALPLIAQVSLQETGIMQDHT
PISEALSRLDALGADIVGLNCRLGPHHMLLTLEEVPLPQKAYLSAYPNASLPAYTDGKFH
YEGDAEYFRQSAKAFRNQGVRLLGGCCGTTPAHIRAFSDELKGSPPLEKKEVREPKAKIR
IMPKEAQRDLPPLQDLVKKRQSVIVELDPPRKLETDKFFAGAKALQDAGIDAITLADNSL
ASPRISNEALGYLAKNRLGLRPLIHLTCRDRNIIGLQSHLMGLHTLGLHDILAITGDPAR
VGDFPGASSVYDMSSFELIQMIKQLNEGRSISGKDLGQKAAFSVAAAFNPNVRSLEKAVQ
RLEKKAECGADYFITQPVFSEEKLMEIYEATKHMEQPIYIGLMPLTSSRNADFLHNEVPG
IKISDKIRERMNSLKDDPLQSVREGISISKELIDAAAELFNGIYLITPFMKYELTAELAA
YARSEKLKTARRSRNAKDFSI
>G8QGH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospira oryzae (strain ATCC BAA-33 / DSM 13638 / PS)|TrEMBL
MNDKTFSIEFFPPQTAEGVEKLRLVRDKLAALKPAFFSVTYGAGGSTRERTFSTVREIVA
AGLDAAPHLSCIGSSRESIRGILAEFQGEGIRRVVALRGDLPSGMADPGEFRYANELVEF
IRAETGDHFHIEVAAYPEWHPQARSADDDLQAFVRKVNAGANSAITQYFYNADAYFHFVD
AVRAAGVTIPIVPGIMPIASFAKLARFSDACGAEIPRWMRKKFEGFGDDADSIKAFGLDV
VTELCQKLLAGGAPGLHFYSMNQSGLTSEIWQRLGLGNR
>A0A088S3H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania panamensis|TrEMBL
MSGLISDAIAAEDANKWYTSYEFYPPRSEKAEENFMKVQIPNFMRQSPVFLDLTWGAGGR
TSETTMRLCKDLQNAYPDTPINMHITCTNMSHDLIKETLDFAKEHGIRNILALRGDPPRG
DEFQANPEGFTCARDLVRYIHITYGDYFCVSVAGYPEGHPSRIPEDGTISDEDHQKELEY
LKEKVDAGASVVITQLFYDASLYVKFVKDCREMGITVPIIAGLLPITTYAGFTRMVSLCK
TRVPGDVKKRVEELKENPEALKEYGVEQCVQMIERIRASGLDYHHLHFYTLNSSAQTFQV
LKRLNALVE
>A0A1I5HXT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. OV426|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSDMEETLWTSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMSAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPSAAAA
>A0A1I7GNP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pustulibacterium marinum|TrEMBL
MKVTEHIKNANGKTLFSFEIIPPQKGSSIEDLYSNIDPLMEFNPPFIDVTTSREEYIYIE
RDNGLIDRKITRMRPGTVGICASLQHKYNVDTVPHVLCGGFTKEETEYMLIDCQYLGIEN
VVALRGDAMKEEKYFRPTKGGHTYASELVAQIFSLNKGEYLHDAVENLTGKEFCIGVAGY
PEKHMEAPSLNYDLKWLKAKVDAGADYVVTQMFFDNQKFFEFVEKAREMGITVPIIPGIK
PIATKRHLQLLPHVFKIDLPEDLIDAVTACKDNKAVRQVGVEWAIQQSKELLDYGVPVLH
YYSMGKSDNIKAVASAIF
>A0A0E9LV92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geofilum rubicundum JCM 15548|TrEMBL
MSTAAQLIRELDQPGFSFELLPPLKGNSIKRVYRTIDALREFNPLFINITSHRDEVVFRD
VEKGLFERKVTRKRPGTVAVAASIQHLYGIKVVPHIICSGFTRSETEYALIDLNFLGIHD
LLLMRGDKSQRDRFFQPSEEGHAHAIDLIHQVNHLNKGVFLDETQSEAFETPFSYGVAGY
PEKHEEAPNMESDIYWLKQKVAAGAEYVVTQMFFDNDKYFEFVRKCRDAGITVPIVPGLK
PLTLLNQLTVLPKIFHVDMPEAFAAELRKCKTDDAAAQVGAEWTTMQAKELLAKGVHLIH
FYTMMATQSVKQVAAHIY
>A0A4P5VFD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp|TrEMBL
MLEEVLARGGFAITAEVTPPRGADVSRTLAAAAHLLGRVHAVNVTDGSRAMMRMCSLAVC
RRLLDVGIEPVLQLTCRDRNRLALQADLLGAHALGIRNVLCLTGDPVRSGDQPKARPVND
LEAVRLLRQVQAFNAGEDPVKGSLPDGATALFAGGAADPHSASWSALKSRITKKHAAGAR
FIQTQMVMDPEPLRRFVEEITAPLGLPVLAGVFLLKSARNAHFINRVVPGACIPEGLILR
LEEAQDPAAEGVKIAAEQVERYRPLAQGIHLMAIRAEERIPEILSQAGISSLDELA
>A0A172T3G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium pennivorans|TrEMBL
MKVTEMVKERRIISIEIIPPKRGEDVENIYRTLDKLMNYDISFISITRHPVEVDYIEYED
KIVKVHKVKRPGTLGLTAALMNRYRIDVVPHLICVGMSKFEMEDMLIDLDIMGVDNVFVI
RGETASSVENYNKGDYKYAVELVRQIKDLNMGKYLYTSAKPTNFCVGVAGYPEKHYESPN
LETDLKFLKQKVDAGAGYIITQMVFDAQVYKDFVERCRSIGINVPIIPGVKPVVSKSSVF
NIPKKFFVTIPQRFVEAIDNAKTKEEEFKVGIRFTVELVEKLIEYSAPGIHIFTMGRGEE
SCEVIKHTQSILK
>A0A1G6S6D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus faecimaris|TrEMBL
MKITEHLKNAKSTLFSFEILPPLKGQSLKELLEGIEPLMEFKPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFHVDAVPHLLCGGFTKEETENALIDLNFIGVDNV
LALRGDAPKTEGRFVAEKDGHHFASELVEQIIRMNNGKYLHEETETSFHTDFCVGVAGYP
EKHFEAPSLKFDLNYLKEKVDKGAEYIVTQMFFDNKKFFEFERKVREAGINVPIIPGLKP
ITTLGQITMLPRTFFLDLPDALTDELLQCKTNAEVKEVGIAWAIQQSKELVNAGMPSIHF
YTMSKADATYKIAKEVF
>A0A0C3PHI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pisolithus tinctorius Marx 270|TrEMBL
MKLSDKIAAHPAHRPFYTFEFFPPRTDQGFDNLLTRISRLSNLDPIAISVTWGAGGSTKD
RSLDLAGITQADYGIDTILHLTCTNMVPGLVDDALRTAKARGIQNILALRGDPPRGQEHW
TPIDSRFSHGVDLVKYIRSSPEFSPHFCIGVAAYPEGHPDNQTDDDVNFDVLKEKVEAGA
DFIVTQLFYDADRFLHWLERVRREGISVPIIPGVMPIPTYSSFLRVVNLCRIQVPPSIMI
DLEPIRHDDQLVKEYGIRLAVDIILKVTGNGDIRGVHFCTLNLEKSVQLVLERLKWAGGS
PTTRNKLIADSPVPLPPISELVVTPTTATSDAAAALTSKTTVEIEPPGRGEINNAATWDD
FPNGRFGDYKSPAFGAQDQWGGLGLSVHPVHPDWGNPATAEELTDLFLRHLDSKAASTPF
SSSPLSAESQTILHQLKALTRGGLWTVCSQPAVDTLPSTDENFGWGPRDGYVSQKAFIEF
FCTEEVVDKIEKKIRLSGGGSVHYFAANLQGDFRTNVPEDARNAVTWGVFPGKEIVQTTI
IERESFLTWKEEAFSIWTEWASFYPPGSDQRTMLDEVRRTRWLMSVLHHNFKNPGALWDF
LVDFYS
>A0A2G4HNF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. Baikal-G1|TrEMBL
MVQGVLQLQQVLEAGGFAVTAEVMPPRGGDLAATLAVARPLRGLVHAVNVTDGSRAVMRM
CSLAVCRRLLDEGIEPVLQLACRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAGDQPA
SRPVNELEAVRLLQQVTAFNQGLDPVSGLLPDGPTSLFPGAAADPQSPSWSGLKARIQRK
QAAGARFVQTQMVMDAEALRRFVGDLAGPLGLPVLAGVFLLKSARNALFINRVVPGARIP
QAVIDRLAAASNPADEGISIAAEQVACYRGIAQGVHLMAVKAEERIPLILERSGLVISPR
P
>A0A1A5HQ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium loti|TrEMBL
MSARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A671QEW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus anshuiensis|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPSGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAETFLRF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDALAPETNLLKDELEKVNRRGI
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWVKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFALLDSPRATQEEGSQS
>A0A5K7U2K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. KU43P|TrEMBL
MSLLKSALRDNTFVCVMEFVPKPSAQRFAAMQVIMDRGHLCGWPMTLAIGDRVASALDLS
PLDALASFETPLPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHHPGERP
VRYLESVAALQIARQACPHWLLGAALNPFKYREEEGGAQYLKAQKKLAAGADFLILQLGF
DASKHQEALHWMKRQATPKPLLACLMSLTHGRAAMLDHVAGVTVTPSMRTLLEAEAAESK
AFAQARSVDRLALQIIGVRLMGYAGVHLSGVHEVEQLLALETRLEHWQTRIHSLAQWAPA
WAQSWQMPNLPAVTFHPPLADWRDGQSVVTATARETWRYHLLHGLHAALFGRNNGLSKAF
GWAVRRPLWATGKGAQLLHKLERSVKRPLLGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKSVGQTAVLAERLIPCIEAQSRHRSSWPQWFEAQPA
RRLNPQPTPRSQPES
>A0A830GPD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomicroarcula pellucida|TrEMBL
MTPQDGVENLLTNARFELMPFESFEEEITHLPDGATIAITTSPQLGIEATLERTEEAVEQ
GFEVVPHIAARYVRDREHLADIARRLTEAGITDIFVPGGDRDEPEGEFESAYDLLSTLDG
MEYSFEEVGITGYPEGHDFIDDETLAESMEQKAPYATYIVTQLCYDPETVLEWIEEIRER
GVTLPVEIGIPGVMKYKRLLQISQKVGVGDSIKFLRKTTGVVGFIRQLVGSRGTYKPDDL
IDGLAPYVDDEEYNISGVHIYTFNQTPDTMSWRYERLEK
>A0A8E6KFU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Paratyphi B str. CFSAN000541|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7T4B965|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter deleyi|TrEMBL
MKQALDERRFACVLEVIPQQSPVRLAALEPIVQRGHLAGWPLLPAFADRVGLHSDLSPLE
GAAALDDPSASLLHFSGKDRERADLLRQMAAMQARGLKQLLMLSGDRLPGHQPGQAPVRY
LESVPALQIAREHGPDWLLGAALNPFKYREEEGAAQYLKAQKKLLAGADFLTLQLGFDAA
KHLEAQAWMRAQGRGKPMLACVMQLTARRAAVLRDVPGIVITDAMRELLRREQQLSPAHA
SACSLERLALQIVGLQWMGYAGVHLSGVHTLDELLSLEQAITRQRDAVTSLSDWVERWQA
SWRMPGMPEVCFAPDTDTWALGQSDVAATPGERLRYALLSTVHEQLFNRTGWLGSAFGWS
VTRPFWKTGVAAQALHAVERTLKRPLVGCDTCGTCRLQDTLYVCPETCPKGLANGPCGGT
RLNRCEFGDRECVHSVKYRIAKSADQLPALAQTLIPGIEVGDRHRSSWPAWFKPEDPTPG
NDCQSLPKSG
>X0KHA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium odoratissimum NRRL 54006|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGFTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHADYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDDVKGDDERVKMVGVDIVSELIDKIKTIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A317PHG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea marina|TrEMBL
MSATARTTQPAAASRIKVSFEFFPPKNGDMESQLWESITRLAPFEPEFVSVTYGAGGSTK
MPTLNTVSRISAETTLSPAAHLTCVGSPREVVDGVAREFRSVGVKHFVALRGDPPEGVGS
AYRPHEGGYANAAELVAGLRGIDDFEISVAAYPEKHPESSDFATDIDMLKRKIDAGATRA
ITQFFFDNDTYERYVERVRRAGIYVPIVPGILPIHNFGQVARFAALCGTSMPDWLARRFD
GLEKDPETRALVAVAMAAEQVTDLVERGVDDFHFYTMNRAQLVYAICHLLGLRGNGGTTS
SGDKPGSVGAAA
>A0A5S4YRM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium hipponense|TrEMBL
MSGAMTDLTTPAQAEGHLAGKRPAISFEFFPPKTEDMERNLWDTINRLAPLEPNFVSVTY
GAGGSTRERTHSTISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGD
PPGGIGTAYAAHPDGYQSSADLVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKAK
VDAGATRAITQVFFDNDLYFRYLDRVRSRGINIPIVPGIMPMHNFKQARAFVTRAGTSVP
DWLAEKFDGLDDDPDTRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGI
RAKSAQKAA
>A0A4P6XAH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. AAP5|TrEMBL
MTTIPAIHPAWTRAPTGMTDGYSLEMTAKDRPALREAADRIAPDTPVAITFLPGETIDAR
IAAAVEVRTLGFEPMPHLSARRIASLDELSATVERTVAEAGVRRMFLVAGDPPTPVGPFA
DTMALLQTGLFERNGITAIGIAGHPEGHPAMDSATCLAVLKAKRDEIAARGMATLIVTQF
GFDPDPFITWLEDLRANGIDSPVRIGVPGPAGIKTLLRFAAHCGVGASVSALGKYGISLT
KLLGSTGPDALVDRLAERLTPEHGPVRLHFYPFGGLVRAVDWIKAYEGRAHD
>A0A7L4QW92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon|TrEMBL
MLSTFNDALNSDRFIVTAEVAPPKGTDISAVLEDAELIRGWVDAINVTDNQRAVMRMGPV
AVGKLLMDAGHEVIVQFTCRDRNRLALQSDILAASALGIRNLCVMTGDYPTKGDHTGAKP
VYDLDSVQLLSVITKMMGGHDMAGNELAGAPSFTVGAVSNTDAARRMQMIKLKKKIDAGA
RYIQTQAVYDVEVFGEFMDSFPDPDVPVLAGIIPLRSAGMARFMNANVPGIRVGDEMISR
MENAEDPVKEGLEIAAESIRELRKMCRGIHMMPIGGNSNTTKLLQMAGISALQ
>A0A3R9HBA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. FDAARGOS_559|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKHHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KKAKSFLIKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
SGKEFSPEITHFSCQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKDKLIPTVPLETRGTSSWKNWYLATEA
>A0A7C1C7X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
RDNGIDNILALRGDPPREAEDFDPATGEFRYAKDLVEFVGKYNYFSIGVAVYPEGHQEAP
SLEADIEYTKMKVDAGADFAITQMFFDNKYFYDFLERARKKGIDIPILPGIMPITDLVKI
KKFTSFCRTTIPSGIEEMMSGVLDKPEEMRKIGTELAIRQCEELLDSGVEYLHFYTMNKS
EVVSEIIRALRVF
>A0A7L7MM18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella sp. BO3|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVV
>A0A8H3R312|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus clarus|TrEMBL
MKITDKINNLETSQPFYSFEYFPPKTDEGLNNLYDRLKRMSHLDPLFASFTWGAGGSTID
RTTEMCATAQSLYGLESCMHLTCTNVVRGTIEKALNEAKSTGIQNILALRGDPPRGQEYW
TSCDSDFTHAIDLVRFIRKEYGDYFCIGVAGYPEGNPDSDNKEQDLKFLKEKVDAGADFV
ITQLFYDVNMFVEWRDECRKIGINVPIIPGIMPIQGYNSFRRITNLCKIHIPLDILNVLE
PIKHDDQAVKDYEKSVRLILEKLRFVQTEEERNLRRLNRRRSSAGFGPNDIIRQEPDGSL
PTAKPVIWKEKNIDYLGRPEDWDNFPNGRWGDARSPAFGELDGYGVSLRIPPEQALEYWQ
RPTTLDDLKQVFKSYILGEIPALPWYEEPLYAETEAIRSKLVHLNELGFLTVSSQPAVNG
ARSDDPIYGWGPRGGYVYQKAFVEFFASPENFEKLAEKITGNPWVTYYASNRNGDFRSNT
KEDAPSAVTWGAFPGKEIVQPTIIEKVSFSAWKDEAYALWTEWEHLYPKDSPSQRLLKDI
GDNWWLINLVYHNYVNSEEIWEIFFKS
>A0A380U1E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Actinobacillus] rossii|TrEMBL
MSYAKEIDILNHNVADLAGKINVSFEFFPPKNEKMENMLWESIHRLKNLQPKFVSVTYGA
NSGERERTHTIVKNIQKETGLVAVPHLTGIDATPDELRVIAKDYWDNGIRGIVALRGDEP
PGYAKQPFYASDLVALLKSVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRAIT
QFFFDVDSYLRFRDRCVTVGIDVEIIPGILPVSNFKQLQKMAAMTNVKVPSWMGKMYEGL
DDDKPLVTLWRRILRWKW
>A0A062H0K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 72431|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGEHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A5J6KZG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium caowuchunii|TrEMBL
MTGKDIPGLEQARATIPAGTKINVTFLGNEDLDMRVAASKAVKDMGFIPVPHISARRLSS
QGQLEEFLGRLQEVGATEHVFAVGGDPAEPEGPYPDSLSVIRSGILQKYGVKEVSIAGYP
EGHPDIPNDVLWRHLEDKSAALKDAGLDAVILTQFAFDTDPVTTWIQGVRDRGIETEIRI
GTPGPAGVKRLIGFARRFGVGANAMIVKKYGFSLTNLMGTAGPDRFVTDLAALLAQNPSS
GDVKLHFYTFGGLLATSQWARDYVAARS
>C5K575|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perkinsus marinus (strain ATCC 50983 / TXsc)|TrEMBL
MGVQNLYERLDRMAELGPMWIDVTWGAGGASSSSNKTFEICRNALTYHGLDVMMHLTCTH
QSVEEIDEVLDKCKEVGIRNILALRGDAPTQSSEWRACQGGFSHAVDLVRHIRGKYGDYF
CIAVAGYPEGHLEAESIEEDLVHLKEKVDAGADLIITQLFYDTEVFFKFVAAVRKLGIRV
PIFPGIMPIQSYSGFKKMTEFCKTKVPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIM
SYGVDHTHSSGGLHFYTLNLESSVCRIIERLMMVDNHVATRVLPWRPSKASSRQEENVRP
IFWRNRQKSFIQRTSSWDEFPNGRLGNQASAAYGDFELNFRSYSKETQDKVFTDFIKGEV
KRLPWCTEPPTEETLFIQKQLIRLNQCNMLTINSQPRVNGALSTDPYVGWGPAGGFVYQK
AYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKVRSNIPPQGQVNAVTWGVFPNS
EIIQPTVVDVTSFMAWKDEAFALWNEWMDVYPEDDHQSRQVLNFIRQHYFLCTVVDNDFV
AGDLFSKLTKICTPIPWETLRIENPSESDGHEVPEVSERFSFI
>A0A522UZ78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MKSGSNLEKVIKSGQPAVTAELGPPMSADAHEVIKKANQLKGFCDAANITDCQTAVVRIS
SIAAAYIALREGLEPVMQMTCRDRNRIAMQADFLGAAALGLKNCLCIAGDHQSFSAAGRL
KGHPGAKNVYDVDTCQLVGIMKKMRDEGLQQGGDKLEVAPKFFIGASWTPMGDPIDFRPY
NLKKKVDAGADFIQTQGIYDMELFKVQMEKARNLGLHERTAVLAGIIVPKSAMMLKYMDS
SVAGVSVPKELIQRMLKAKDAAGDDKKKAKELQEQEGMKITVELIQQALEIPGIKGVHVQ
AIEWESAIEHIVKAAGLYPRPDFSE
>A0A1E4BM94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. SCN 70-18|TrEMBL
MTGKDVAALEEAASAIPPGTKINVTFLGNEDLDMRVAAAKAVADLGFIPVPHISARRLAS
EAQLEEFLGRLQEVGATGHVFAVGGDPAEPEGPYPDSLSVIRSGLLQAHGVTEVSIAGYP
EGHPDIETDVLWRHLEDKAAALKEQELGAVILTQFAFDTDPVMTWIEQVRDRGIDAQIRI
GTPGPAGIKRLIGFARRFGVGANAMIVKKYGFSLTNLMGTAGPDRFVSDLSTLLAAQPAS
GDVKLHFYTFGGLLATAEWVQQYGASTSSEPRS
>A0A553V1V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus detaillensis|TrEMBL
MTSVLAEPVQTAPKLTRVSVELVPRSRTSLRTELAELSSSLGNVQVVNIPDFLRYRMRSW
EACQMALEHVPEAIPHIRAIDINPREPLKMGDFLRQHKISEVLIIEGDAPSDMSQHTYDV
TSLDIIRKFRRELPEIKVWAGLDPYRQSFARERDYAEAKLEAGAVGFFTQPFFDRRLMDV
WAELLPTQQVFWGATSVTTERSFSYWQNRNKAVFPRHFTPTLDANRAWAQEVLSFASEVG
GHTYFMPIKESLSEYLGGIL
>A0A1X1J2W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. dentisani|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLNKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A0P9CX54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kouleothrix aurantiaca|TrEMBL
MTRASAPTSPAPATISRLERVLRSGRFAVTAELDAPDSADPADVYKNALVLAEVCDAINA
TDGSGANCHMSSLSCCALLTRAGYEPVLQVSCRDRNRIAIQGDLLGAAALGVRNVLCLTG
DDVTYGDQPEAKRVFDFDSIQLLQVARTMRDRGVFLSGRKLTTPPRMFLGAAENPFAPPY
DWRPHRLAKKVAAGAQFIPVQTQYCFDVPRFERFMQGVRDLGVHEKVFILVGVGPLRSAK
AAEFMRTRVPGVWIPDALMDRLNKTPKNRQAEEGKQICIEIIQQ
>A0A841IRT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis algeriensis|TrEMBL
MLAAPTRPTAARSPSARPRHIRDLLRTGEPMFSFEFFPPRSPEANQRLWRAIREIEALGP
SFVSVTYGAGGSTRGMTVETTERIATDTTLLPVAHMTLVEHSVAELRHLIGRLADAGVSN
MLAVRGDPPGDPTGEWIPHPQGLTYAEELVRLLKDSGDFCVGVAAFPYKHPRSEDVATDT
ERFVRKCEAGADYAITQMFFDPEDYLRLRDRVAARGCDVPIIPEVFPVVRTSFIPRSEQL
SGAPFPAALAERFASFGDDAAAVRAFGIEYAQRMCERLLDEGAPGIHFITSNQSTATREI
YREVAGRRPSGAAGRP
>A0A6N2E9K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MHIKALLEKNKPAFSFEFFPPKTPEAAEALFTTISDLEPLEADAVSVTYGAGGSTKGLTH
DLVLDIRKRSKLTVISHLTCVDATRAETHEILQTYVDSGIENIMALRGDPPGGTRSFEPH
PEGFTYALELVEYIRKHFPGLGIGVAGFPEGHPATSNRLLEIEHLKAKVDAGADYICTQM
FFDNHEFYDFVERCRHSGITVPIVAGIMPVPNRKGMNRMAELAAGTRFPAKLLKALDRAE
TAEYFENVGVHWAASQVMDLLDNGVDGVHFYTLNKSLATRRVYESLGLHSTKAVRSA
>A0A6H2F798|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae endosymbiont of Plateumaris sericea|TrEMBL
MKYFCIENKEYIDKFFNKSFNKFNISFEIFPPLNYEIKSKFWNIIKTLVILEPKFISITT
HRRDVNNFYNNTYNIVKKIQKYVNVELAPHITCINTKNNELYNIATKYWKNGIKHIVALR
GDKIKSNTNINSLMYASDLVYFLKQIANFNISVAAYPELHPESQNIKEDLINLKRKVDAG
ATRAITQFFFDIETYLLFRDRCISQGINIEIIPGILPITNFIQLKKFIKITNIKIPYYIN
NMFKNLNTQDDSTCKLLGSFIAIEMIRRLKNEGVNHFHFYTLNKSEIIYAICLYLGIKPN
KFIFNQKK
>A0A662Q0D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MNVDRRRAGCPKRVLNGPCGGMRADGTCELGDARCVFADSQPSEIILDPGFRFRPKLKKR
KPFTRLLSKVWSEVVWVAEIPPSFEAAEKIQVLKDLSFSALSIPDNPLATLHLESSAFAA
YLKKALGCEVIVHLTCRDLNRLALKSRLLALQLSGVEHVLALTGDYPSIKSGSYSTPIFD
LDSIRLIYLARIMSDHGVDELGNPTSRSLRIQVGAGLNPYLPIEVEVSRALRKIEAGAEF
FITQLVFSLERIESLLKSLRREGVTIPVFPSFLLASGDRAQKVLKAIGVPAELPTNLNAL
TEAYLGILGRLRRLYGPVGAFISTLGKLEDLKIWDEAFKSLY
>A0A7V2ZLJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacterium album|TrEMBL
MKVIEHLAKAKNPLISFEIIPPKRGGDISSILSLLDDLVKYNPPFIDITSHAAEVYYDET
PQGIKKIIKRKRPGTLGICALIQNKYNIDAVPHVLTKGFTREETEDFLIELNYLGIQNVL
AIRGDDSGYNKPIPQGRSANQYAVDLVRQIMDMNRGKYLEDSLLDAKPTNFCIGVSGYPE
KHFEAPNLKTDIRFMKEKIDAGADYIVTQMFYDNKHYFRFVEIAREMGVTAPIIPGLKIL
TSKVQLNTIPKNFYINIPEALSDEVNAAKPEHVIDIGVEWAAKQVEELLNNNVPAVHFYI
MQNSKPIVKLMQKLKL
>A0A6J0XRC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odocoileus virginianus texanus|TrEMBL
MDRPKPKVFPVGHCCPSLGMRASEAGSRRFSVPPSISRNSAMVNEPRGNGGPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEAESFEADLKHLKEKVAAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGAELTSEESVFQVFAHYLS
GEPNQNGYKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNL
VDNEFPLDNCLWQVVEDTFELLSRPPQDERETEAP
>A0A6P0ZIW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerospermopsis sp. SIO1G2|TrEMBL
MQDSHSTSALNNFRKAVVAGDFLVTAEVAPPKGGDPSHMIEMTATLKGRVHAVNITDGSR
AVLGMSSLAASVILSQQGIEPICQIACRDRNKIGIQADLMGAHALGIRNVLALTGDPVKA
GDHPDAKPVFDLESIRLLRLIRNMNEGFNYNQKSLKDGALDIFPGAAVDPQLKSWSGLQS
RFAKKVEAGAQFFQSQLVTDFEKFEKFMAQIASEYNKPVLAGIFLFKSAKNADFIKRMVP
GVHIPDQIIDRLAKAEHPIQEGMKIAAEQVKIAKDLCQGVHIMAVKREDLIAPILDLAGV
GKVN
>A0A6N2E3C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MHVGDIFAAHKRSFSFEFFPPKTPAGSEKLFATLSQLETLKPSFVSVTYGAGGGTRDRTH
DLVLRIKKETQLDPIPHLTCVHQSRSELEELLVRYAEAGVDNIMALRGDPPQGEQHDPAA
EDFPQAVDLVSYIREFNGRGIHPNSRGFGIGVAGFPEGHPATPNRLLEMQYLKEKVNAGA
DYICTQLFFDNRDFYDFTERCRIAGITVPIVAGIMPILNQRSFERTPELALGARYPAAFL
KGIQKCANDTEIANFGLEWSVRQCYELLAQDVEGIHFYTLNHSPVTIEIFRRLGLSSSFA
AEFADT
>A0A2T2TJV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QS_1_63_11|TrEMBL
MKVTEHFDQASEPLISYEIIPPKRGGSAEQMLEVVEELMPFDPPFIDVTSHSAEVEYKQK
DDGTWERCVKRKRPGTIGLCAAIEARFGIDTVPHLLCKGFTCEETEDALIELNYLGIDNV
LAIRGDDKGYKKSISENRSRNEYAVDLVQQIQDMNQGVYLEDLMNAEPTDFCVGVGGYPE
THFEAPNLAWDIMRLKEKVDAGADYVVTQMFFDNEYFFRFVDKCREVGIDVPIVPGIKIM
KRKRHLRTLPKYFHTEIPEELAAEINAADPEDVEKIGVDWAIRQAHELMEADVPCIHFYI
MSSADTVKKVVEPLREPKEMA
>A7TRT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)|TrEMBL
MSSIRELYDQRSTPAVSLEFFPPKTEIGKRNLLERMGRMSAMDPLFVTVTWGAGGTTAEK
TLELATLAENSLNLNVCIHLTCTNMSRGIIDEALEACKKIGIRNILALRGDPPIGEDWND
MESELNEFKYAIDLVRYIKQNYGDYFCVGVAAYPEGHHEGELDSNDHEPHKDLPFLKQKI
EAGADFVITQLFYDVEKFLKFEELFRREVSDSIPLFPGLMPINSYSLFHRAAKLSHASIP
QHISERFSPEIQADDHAVKAVGVEILIEIINEIYQRTSGRIKVFHFYTLNLEKATAQIVT
GCPLLSHILEEDQDDDSLIDNEDVIMTDDKGGENDVELGQTNKRRRHSSVNSNSMASGPL
VIDRSGLRRDSIGLTVPSRKVLISISQGSGTLGRNATWDEFPNGRFGDSRSPAYGEIDGY
GPTLKVGIKKAYDLWGTPKSVIDLKSVFIKYLEGSISALPWCDLGLSPETALIQEELIQL
NQRGYLTLASQPATNASPSTDKIFGWGPKNGYVYQKAFVEMFILKKQWEAIVKPKLDHYP
RGKFSYYVGDSSGSFESNLETNSSNVVTWGVFPNSPVIQTTIVEEESFKAWRDEAFCIWL
EWAKLFPSNELSNSFLKQVHSTYCLVSIVHHDFSETDELWEMLLD
>D2RBG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis (strain 409-05)|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGINAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQESAGVFEHASDL
VYYIRSKHPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNADCLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A1I6ZJG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sedimentitalea nanhaiensis|TrEMBL
MTVPSISFEFFPPQNLEGSFRLWDTVQTLAPLDPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNATRAETMAIADGFAKAGVTDIVALRGDPPKGSGAFAPHPEGFANSI
ELISALAETGKFNIRVGAYPDKHPEAADLAADVNWLKAKLDAGATEALTQFFFEAETFLR
FRDACAAAGIDAALTPGILPIENWKGARAFANRCGAQIPAWVDDAFDKALRDGREDLLAT
ALCTELCSDLIDEGVDKLHFYTLNRPELTRDVCHALGVTPKVQLQNVA
>A0A2Z3FXR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium fredii CCBAU 25509|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMEIQLFQTVADLSSFAPAFQTVTYGAGGSTKAR
SLTTVKRMIGEMGLRNTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGSA
YQPFPGGYESSAALVNALRARGDFEISVSAYPEKHPESSDVAADIDMLKRKVDSGATRAI
TQFFFDNDDFERYLERVRRAGVQIPVVPGILPINNLTQVIRFAGLCGSKVPEAIVSRLGH
LDDQPEERFKEASHIAAEQIVDLARRGVRDFHLYTMNRSPLIAAVCDLVGYGRRPANHTA
APSYRAVATA
>A0A1G3B251|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RIFCSPHIGHO2_02_FULL_40_12|TrEMBL
MSENNDTNNFKAGSNLEKLLRRGEFVVTSELGPPRGASREAVEKKAEILKGYADAFNITD
CQTAMVRLSSIASGAILLNMGMEPVIQMTCRDRNRIAIQSDILGAAGLGMKNLLCLTGDH
QCFGDHPDAKGVFDVDSIQLLDIVRQMRDEKRFQSGEELKVEPRLFLGAAANPFADPFQF
RAIRLAKKIKAGADFIQTQIIYNVEKFEKWMGIVQDMGLHKKVFILAGVTPIRSLGMAKY
MKKSVPGMDVPDEIIKRLEGAENKQSEGINICLEIIGRVRKIEGVSGVHIMAVEWEEIVP
EITERAGLLPRPTP
>A0A1Y2DWJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucosporidium creatinivorum|TrEMBL
MVKISDKIRESERKGQPWWSFEFFPPRTNDGWVNLYDRIERMKLLGPIFVDITWGAGGAT
SEATTAFVKTAHSELGLETCMHLTCTNMPVEMVDAALKDAKESGCRNILALRGDPPRGTE
EWTAAEGGFNHAIDLVKHIRKNYGDYFDIGIAGFPEGHPHSESPEKEMYHLRKKVDAGAN
VIFTQMFYDADVFIDWGRRVRAAGITIPIVPGIMPIQTYAAFKRRTDFAKTIVPQQVWDM
LEPIKDDDLKVREFGTKFVADMCRKILAADIGINGIHCYTMNLSRGTEMLLEELNFVATA
DVVKPLPWRLSLTQKRRTETTRPIFWSNRQRSYLSRTADWDEFPNGRWGNQASPAFGDIT
SLALSLPHNVKDATTLWGTPRSLSDISALFAAFCRGQLKALPWSDQPAAKETTVISEPLA
RINEAGFLTINSQPRVDGASSSDPAYGWGPKGGYVYQKAYLEFFTSPEHLEKLLKLIEAN
PWTTYHAVNKQGDLRTNAAEGPNAVTWGVFPGAEVIQPTVVDGEAFLAWKDEAFELGSLW
ASLYETSSPESAKAISEVFDTFYLVNIVYNDYRDPNPDAIFAPFYSLFPETSPSSSPKPE
QANGTSLAN
>A0A640VWP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseobacter cerasinus|TrEMBL
MPTPSVSFEVFPPRSIDASFKLWETAQALAPLEPRFFSVTYGAGGSTRDLTHDAAYTLRK
SSGLPVAAHLTCVGASKSETLAIAQRFAQAGITDIVALRGDAPEDQDHFTPHPDGFANSV
ELIEALAQSGQFTLRVGAYPEKHPEAATQAANIDWLKAKIDAGAAEAITQFFFEAETFLR
FRDDCAKAGITAPITPGILPIINWQNARKFALRCGATVPGWLDQAFDAAIRDDRHDLLAT
ALCTELCSELVDEGVESLHFYTLNRPEMTREICHALGVTLATTGVRDVA
>A0A356EI03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MNTVLETLRSRNQPFSIEVVPPSRGGDHNDVLVSVDSLMPWQPAFVSVTDHPSGRVWTEH
AGQPVQVPLRSKPGTLGLCVALRAELGLWVVPHLVCIGNNSFRAEDELIDLRYSGFSDVF
VIRGDERFVPAAIGGAPSGDGQASSASQGLVQSAVRNDRLGCAADMVRLVMGMNRGQYAG
GTLQGAPAGFTVGVAAYPEKHPAAINPDYDLLELKRKVDLGASWIITQMLFDATVYRRFV
ERAREVGIAVPIIPGIKPIVRKKSLRAVPGSFFIDVPQSLAKAMDEAASPAEERLVGIKF
AAKLMSDLYDVGAPCVHLFTMGKARDTLETLSAVFGGGGRQEAGV
>A0A8I1RT03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afipia sp|TrEMBL
MTTETTTPDARAQKRPAISFEFFPPKTEEMERGLWDVVTRLAPLNPNFVSVTYGAGGSTR
ERTHSTIARILGETKLTPAAHLTCVAATKGDIDEVVDRYHDVGVRHIVALRGDPTTGIGT
RYAAHPEGYQQSSDLVAAIKRNHPDMEVSVSAYPEKHPESKSLDADIDALKAKVDAGATR
AITQFFFDNDLYYRYLDRVRAAGITIPIVPGILPVQNFKLAKNFATRAGATIPDWLEAKF
EGLDDDADTRRLVAATVAAGQVQKLAKQGVENFHFYTMNRADLVFAISHLLGIRPNSTQK
AA
>A0A854PSP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp. KAs 3-5|TrEMBL
MSESISPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLRDILQAYKGEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQATNPSADLAHFVSKVKAGADAAITQYFFNADAYF
DFVDRARAKGVSVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHSEAPLAIWKELTV
>A0A437B814|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chilo suppressalis|TrEMBL
MQSRSGVRLSAIQYNIIITTQNQVEKVGYYCIFLHFITLDEEMAKITDLLRITAAPSYSF
EVTPDVHEADLDNLPLEPTFFSVTWHAKSHLNKDLDIAPLKLAKLLRSKNKNVLLHLTCD
LLRKDYLSKLLQLLQDNGICNLFIMLGESYDPSLSDFQSSDELIKEIRREFGDYFCIGVA
GMPDCNDERLLLLKMKVNIGANFILTQAFFESDVFNQFTRKCKSVQIDVPIIPGVFYFED
YKQLNGFIILCKIKVSQNVLDYVKVKESTVNVAPGKEITRELIRSLYTEQGVNHFHLFTL
NKFDRVCSFLRELEA
>A0A833NDB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas veronii|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMRQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A3JC11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. ELB17|TrEMBL
MYKHLAATADAITGQLRLARFQPYILDINMESQKQFKRRFSFEFFPPKTEQGKIKLQGVR
DELAAVNPDFFSVTFGAGGSTRDRTLETVFSLHQQGISTAPHLSCVGGTRAEISELLDTY
KANGINRIVALRGDLPSGMGAAGELRYANELVSFIREHSGDYFNLEVAAYPEFHPQARSA
EEDLKNFARKVEAGANSAITQYFFNADSYLYFIDRLEKSGITIPVVPGIMPIVNFSSLVR
FSDMCGAEIPRWIRKQLEAYGDDSESIRQFGEEVVTRMCEKLLKAGAPGLHFYTLNQVEP
SLGIWKNLGLGEREKIPF
>A0A0M2V9Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arsukibacterium ikkense|TrEMBL
MAFANAQYLDAINRNLHDVQGKVNVSFEFFPPRTAQMEQTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASKQQLIDIARDYWDNGIRHIVALRGD
LPPGSTAVPELYAADLVEILRSVADFDISVAAYPEVHPQAPNAQFDLLNLKRKVEAGASR
AITQFFFDIEKFLRYRDRCAAIGIDVDIIPGILPVTNFQQLQKFAGLTNVAIPDWMSKAY
QGLDNDPTTRNLVGANIAMEMVKVLSREGVDQFHFYTLNRSELSYAICHLLGVRPVL
>A0A0S8KJJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium SM1_79|TrEMBL
MAQNEYKSGSNLEKVLSRGEFAVTAELGPPKSADFDLIKKKAEILSGWADAVNITDNQTA
IVRVSSIATGKLALDLGVEPIIQMTCRDRNRLSIQSDILGAYLLGIRNILCLTGDHQCFG
NHPAAKHVFDLDSIQLIQMVKNMRDEKVFACGEEIKNSKKAQVKEPRMFIRAAANPFADP
FEFRVMRLQKKIDAGADFIQTQCIYDMDRFADWMRQVCDRGLHKRCKILAGLTPLKSAGM
AKYMRDQVAGVTVPNYYVERMSKADDPKAEGIEIVTEQIQQLRQMEGVAGVHIMAIEWEQ
KVPEIVQKAGLKRKP
>M3B074|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces mobaraensis NBRC 13819 = DSM 40847|TrEMBL
MRDLLASGERSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSVTYGAGGSSREGTVRA
TERIATDTTLTPVAHLTAVNHSVAELRNVIGQYADVGIRNMLALRGDPPGDPTGEWVRHP
QGLHYAVELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVDKCRAGADFAITQMFF
HADDYLRLRDRVHAAGCETPIIPEIMPVTNVRQIERFAQLSNAAFPADLAERIRAVEDDP
AAVRSIGIEYATELCARLMAEETPGLHFITLNHSTATLEIYENLGLHQRS
>A0A2S4TFY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ACNIH4|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKIVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADNFDADIKRFCEKAHAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A3M4PR46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas viridiflava|TrEMBL
MGSMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVL
QLENEVKVPAAPHLSCVGDSKEDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHA
NDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADS
YFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQ
AFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A2G4GZ40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MSRSLLIDALRSPVRPTVSVEFFPPKDAEGGARMLKVADTLKPLGIDFASLTYGAGGTSR
DTTITYGAELVKMGIPLIGHLTCVGHSRTELAGIISQYEKAGFSGILALRGDPPKGQKDF
VAHPEGFAHAQGLVRQIAAEQPDRFAIGVAGFPERHPDAVDDLSDIRFLAGKVAAGADFV
TTQLFLDNEDYFRFVARARAAGVSVPILPGIMPVLSLKQARNFCGFCKARIPDALVRELE
ACGPDEEAQRKVGVSWAVRQARGLVARGAPGYHVYILNKAESAVELFAALRA
>A0A2E4ZXE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MADGESIQECFGAGRTTFSVEFFPPKDEAAADRMLRAAEDLRPYRPDFVSITYGAGGGTR
ETTMRYARALKEDLGFEVMPHLTCVGHTKEELLEILGEFREAGFRAVMALRGDPPKGEDS
FSAVEGGFSHADELVSLARAHFPEFSIGVAGYPEKHPEASDFASDVTHLANKVSCGADFV
TTQLFFDNASYFSFVGSCRAGGIEAPVLPGLLPVGSLSQIKRFCAMCGATLPDELTCRLE
AAGDDSSAVRQVGADWAYGQLAELLDRGAPGFHIYCLNKSKVVIEALERLRADGRFRAE
>A0A2D6UMK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium|TrEMBL
MREAQRALETPLFSGLPGXIEVSFEFFPPKNXKMGETLWRSVETLAPXGPRFASVTYGAG
GSTRERTHQQVVRXQNEANXPAAAHLTCVEATRDQVXEVARHYWDXGIRHIVALRGDAPD
GXGXYRPHPXGYANAVELIAGLKRVADFEXSVAAYPEVHPDSPDRQADLDNLKAKFDAGA
TRAITQFFFDPECFFDFRDRAAXAGIXGEIVPGIMPVLSFAAVQRMSGLCGTAXPDWMEG
LFDGLDDRPEARQLVXATIAAELCRXLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKVA
A
>A0A4R3GP70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK418|TrEMBL
MSQTNDARRRDIRISFEFFPPKSEEMEGQLWNTVRDLQDWNPEFVSVTYGAGGTTKAPTL
STVTRFLTDTPLATASHLTCVSATKEETHQVVDSFRKAGVTHFVALRGDAPGGVGAPYQP
HPGGYANAAELVAGLKQIGDFEISVSAYPEKHPESRDQAADIDMLKQKAENGADRALTQF
FFDNDNFERYLEKVRAAGVRIPIVPGIMPVQNLTQLKRFAGACGTVIPAFLDERFAGYDD
KPEERAKVAAEVAAEQIEDLIRRGLHEFHLYTMNRAPLVSAVLDNLGLSRQGARRAGAAA
>A0A520WW25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium|TrEMBL
LYAGGVRQFHFYTLNRAELSYAICHMLGLRPTGDKA
>A0A3D4HHV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MHLGQSIVDKLAVNQPLLSVEFFPPKTEEGARQILKTAQAIQEIRPDFISITYGAGGSTR
ERTLEYGEILHDLFGFEVMPHLTCVGHSKDDIRQILRRIERRGFRNIMTLRGDAPKDNPE
MTTGTDGLCHASDLVQFIREECPYFCLGVAGYPEKHPEAKSMEEDLQHLKFKVDQGASFI
TTQLFYNNDDYFKFVESCRNLGINVPIIPGILPVVSLKQVKRFCAMCGAKIPPMLEAYLE
AAKDDEEAQEMIGVEWAHNQISELLCKGVPGVHLYILNRAQSTIDLVQSLKQGRLFPKAA
TIAAVTTQLA
>A0A2P5A7D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasponia andersonii|TrEMBL
MKVIEKIREAVGVSEGYQNGRTQKNVVFSFEFFPPKTEDGVDNLFERMERMVAHNPAFCD
ITWGAGGSTADLTLDIANRMQNSVCVETMMHLTCTNMPLDKIDHALSTIKSNGLQNVLAL
RGDPPHGQDKFVQIQGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIGPDGVASLE
AYQSDLAYLKRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGF
LRMTGFCKTKIPAEITAALEPIKDNDEAVKSYGIHLGTEMCKKILANGIRTLHLYTLNME
KSALAILMNLGLIEERKISRSLPWRRPANVFRIKEDVRPIFWANRPKSYISRTTGWDQYP
QGRWGDSRNPSYGALTDYQFMRPRSRDKKLLEEWGIPLKNIEDVNEQFKKLCVGKLKSSP
WSELDGLQPETKIINEQLGKINTKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYL
EFFCTKDTLDALVDKCSRSFPSLTYMAVNKEGRWLSNVDQTAVNAVTWGVFPGKEIIQPT
VVDPASFTVWKDEAFQIWSRGWARLYPEGDPSRKLLEEVENSYFLASLVDNDYIHGDIFA
TFNEL
>A0A378UEF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bergeriella denitrificans|TrEMBL
MSYAKEINALNHNLAELGSDINVSFEFFPPKNEQMAAMFWNSVDRLKVLNPKFVSVTYGA
NSGERARTHDIVKNIKRQTGIEAAPHLTGIDATPEELRRIAQDYWNSGIRRIVALRGDEP
AGYQAKEPFYASDLVALLRDVADFEISVAAYPEVHPEAKSAQADLINLKRKVDAGASHVI
TQFFFDVESYLRFRDRCVTVGIDAEIVPGILPVTNFRQLGKMAKVTNVKIPSWLARMYEG
LDHDQGTRNLVAASVASDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRPQADAA
>A0A510X8M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas pacifica|TrEMBL
MSAQEHPLGISFEFFPPNTEAGREKLMHVRDALAGRQPRFFSVTYGAGGSTQHRTLDTVR
QVRQSGISTAPHLSCVGSEKAQLRDLLAQYREEGIDSLVALRGDLPSGMGGVGELRYANE
LVEFIREETGDHFEIAVAAYPECHPQAPDFERDLENFARKMKAGANLAITQYFFTADAYF
HFAERAQALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSASIAAF
GEEVISELSQRLLEGGAPGLHFYTLNQAEPTLKVLDNLCG
>A0A7Z0C4Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides marinus|TrEMBL
MSIGRGRSLKELIEAGEQSFSFEFFPPKDEAGEEQLWSAVRALEPYAPTFVSVTYGAGGS
SRGTTVRVTRRIAQETSLLPMAHLTCVGHTRAELEEILDEYAAAGVHHVMALRGDPEGGP
RAEWTPTDGGLTYASELVEMVTAREEFRVGVAAFPEKHPSSPSLDHDADVLAAKARAGAE
FAVTQMFFRAEDYVGLVERVRERGVDLPILPGIMPILNLAAIRRQGELIGTEVPTEVVDR
IAAHDGDPVSMRAEGIALAAELCRDLLDAGAPGLHFYTLNRSKATLEIFEKLDVRP
>A0A7Y2IIN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MRSEVENAGQRLARRPWPTTPIRPGIDVSFEFFPPASPSASDQLAECVSQLAPLAPRFMS
VTYGAGGTTQDRTIHVIEELGSSTGVPIAGHLTCVGANRATVDKVIDRYASAGVNHIVAL
RGDLPKDRTNDVHNNTYQDAAALVAAIRSKFPSESFEISVAAYPETHPMATSPEADIENL
KRKIDAGATRAITQYFFDNNHFLRFLERARGAGIAVPIVPGIMPVTNFASIARFSERCGT
SIPSWLPDLFGGLDAMPEVGNLVAATVAAEQCRELVEHGVREFHFYTMNRPQLSLATCHI
LGVRPNVTATTTQAVAS
>A0A8I1AXE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ACIN00229|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLRIVHQELQLLNPDFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKTQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTHQLVVDLGLN
>A0A807ALX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium ciceri biovar biserrulae|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A4D8XRN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perkinsus sp. BL_2016|TrEMBL
MVLPNILQSIDGDHESGNTRRLDFSEHSIPTLSFEFFPPKTDQGMANLMKRMASMSDMKP
EWIDVTFGAGGSTKHRTLEICEMAVKDFGMNVMMHLTCTNMSRNDIDSVLAKMKSIGIRN
VLALRGDPPTGTTEWISSDSGFSHAVDLVRHIRSEYDDYFCIAVAGYPEGHADSDSFESD
LHFLKEKVDAGADVVVTQLFYDTEAYFEFVQRLRHLGVKVPVIPGVMPIISLPSLKRMAS
MCRVHVPDAILNDLEAIKDDEEAVRDRWSSYIYNEQ
>A0A6H9GCF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa NIES-3787|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILHQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSRSGLQSRFERKIEA
GAQFFQSQLVTDFDCLDKFMQEVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDMAGIPPIHN
>A0A7Y7PMS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter lapidiphilus|TrEMBL
MKVTEHLTRAEGKTLFSFEVLPPKKGENIQTLFSNIEPLLEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFTKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFMPEPDGHSYACDLIGQVSDLNKGEYLDEAQDDTWATDFCIGTAGY
PEKHFESPNYGADLRYLKHKVDRGAEYIVTQMFFDNEQFFAFERRCREAGIMVPIIPGLK
PLTTKGQLTMLPRTFYLNLPEELADAVHLAPDNAAARQIGLEWCINQSRELMAHGVPCLH
YYSMGKSDSIRQVAAALF
>A0A845PUA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia argenteiflava|TrEMBL
MKITHHISQSKGKTLLSYEIIPPQKGYGIEDLYKNIDPLMEFNPSFIDVTTSREEYIYIE
KAEGLMERRISRMRPGTLGICAALQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDPMKGEKYFEPSKGGNRYASDLVSQISDLGKGKFLDGEVSGTSTHNSFCIGVGG
YPEKHLEAPSLLYDLNMLKKKVDLGADYIVTQMFMDNSKYFDFVNKAREIGIKVPIIPGI
KPFAIKKHIKLLPQAFKIDIPEDLVNAVIQCKTNEAVRQVGIEWCIQQCKELLTFGVPAL
HFYTMGKSDNIQKVIREFF
>A0A5B9YIW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulosilyticum sp. WCF-2|TrEMBL
MIEKAIKHAKKPSFSFEIFPPKGTADLSGVYATIDGLASLAPDLISVTYGAGGSSRENTV
DIASAIQNKYDIPALAHLTCVGSTKAEMDDILTHLKDKGVKNILAMRGDLGENAVLGDFK
HASELIAYIKENYDFKVFGACYPEKHIEAYSMGEDLKHLKHKVECGTDELISQLFFDNNA
FYSFIDKVRGIGIGVPVVAGIMPVTSAKQIDRMVSMCGATLPEEVQHFVKAYGHNSMAIK
EAGIAYATSQIIDLLANGVDGIHPVLIQEERRTLWFVMF
>D6KJ56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. 3_1_44|TrEMBL
MMTLKEKHQQGQFTITVELDPPKSSSAEKTFEQAARLKGNVDAINIADSPMSKMRMSPIS
LSYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQS
VFEVDCMGLLNIAKTLNAGKDLAGNDLDAPTNFYIGATGNPGAPDLEIERQKLAAKIQNG
AHFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILD
RMEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLYIIDHV
>A0A1Y1SA17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanococcus atlanticus|TrEMBL
MKYSFEFFPPRTDKGRDNLRQTWRELAAFDPEYFSVTFGAGGSTLEGTFDTVKAISEDGH
NATPHISCISATREGVNTLLQRYRDIGVKRLVVLRGDIPSGMHSPGEFRYANELVSFIRA
EHGAHFHISVAGYPEVHPQARSAQADLDNFVRKVEAGADVAITQYFFNADGYFDFVERAR
AAGVRIPIVPGIMPITNYAQLARFSDACGAEIPRWLRQQLAALDGGDNTDALIELGHAVT
TRLCQQLRSGGVDELHFYSLNKAEPTVRILNALG
>G3IHM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cricetulus griseus|TrEMBL
MVNEGSGSGSGSESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAE
GAVNLISRFDRMAAGGPLFLDVTWHPAGDPGSDKETFSMMIASTAVNYCGLETVLHVTCC
QQRQEEITGHLHKAKQLGLKNIMALRGDPVGDHWETEEGGFSYATDLVKHIRSEFGDYFD
ICVAGYPKGHPEAESFEEDLKHLKEKVSAGADFIITQLFFEANTFLSFVKACTEIGISCP
ILPGIFPIQGYTSLRQLVKLSKLEVPQNIKDVIEPIKDNDAAIRNYGIELAVSLCRELLD
SGLVPGLHFYTLNREVATMEVLKQLGMWTEDPRRPLPWAVSAHPKRREEYVRPIFWASRP
KSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESV
FKVFERYLSGEPNQHGYTVTCLPWNDDPLAAETSLMKEELLRVNRLGILTINSQPNVNGK
PSSDPVVGWGPSGGYVFQKAYLEFFTSREIVEALLQVLKKYELRVNFHIVDVQGKNITNA
PELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQY
IHDNYFLVNLVDNEFLLDNCLWQVVEDTFELLNGHSVKGDAQAP
>A0A2S5SSL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zhizhongheella caldifontis|TrEMBL
MQATPDRLPVSLEFFPPKTPEGVDKLTTVRAQLYALRPEYCSVTYGAGGSTQGGTLQTVQ
SILSEGVDAAPHFSCIGATRDSVRAQLEQFRQMGIRRLVALRGDLPSGYGGFGEFRYASD
LVAFIRETTGDHFHIEVGAYPEVHPQARSPEADLQAFATKVRAGANAAITQYFFNSDAYF
RFVDDVHKLGVDVPIIPGIMPITNSSQLMRFSDACGAEIPRWIRMRLAAYGDDKASIQAF
GLDVVSDLCDQLRVAGAPGLHFYTMNQAHATLQICERLGLR
>A0A2W6CDP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MAKIADLLRQGRTFSFEFFPPKNDVEQATLVRTLRDLEPLAPSFVSVTYRGGSASRQRTH
DLVAGMLRTTTLTPMAHLICVAHTRLELAEILVGFAKAGVENIMALGGDPPADLATGRLA
TADSASADSAPAGRPKRGGELTRAIQLVELAQVIGGFSVGVAAHPVGHPRSPDLAADRDH
LAEKLAVADFAVTQFFFRAEEYLGLVGDLAARGMTKPVVPGIMPITSLSSLPRMAAMGAA
VPPEMAERLAAAGDDSQAVRKAGIEMATELCDALLVAGAPGLHFYTLNRSTATREIYANL
GLVPPPEPPEEPWPAQTSQPAQPPRPATPDPL
>A0A089JWG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL R5-0912|TrEMBL
MKPDLRSAWENNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYMEAGSVL
LESNTYSANYDKLSKFGLEAKVAEINRAGVSIARRAAGETGYVVGAVGSIRAGKRANLSS
AELKRFFSQQIAALLEEQPDGIMLETFYDVEELHLALRTVRKLSGLPVICQLAVDDSART
LDGLTLPEAFRILEQDGADVIGFNCNTGPNGIKRALGTLQGRLVLPVSIYPNAGVADYVD
GQYRYGASPEYFGQMAPVFADMGSRIIGGCCGTTPRHIAEISAALKDYAITPLPEPDEHR
MAERISVHEHLSEDEGQGGAEPTLVDLVKERHTVIVELDPPRDLDIAKFMRGAEALRRAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIRQLNDGVAFSGKPLKQKAKFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIARIAKATEHLDIPIFIGIMPLASGR
NAEYLHNEVPGIQLSPEVRSRMQGLEGEAGRAEGVLIAKELLDAATAHFNGIYLITPFMF
YDMSVQLLEYVWAKQGRRLSPLFR
>S0G256|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotignum phosphitoxidans DSM 13687|TrEMBL
MTATQSGSNLEKVLTAGHFAFTGECGPPKGANVAHLRKKFKYLKGNVDCVNMTDNQTAVV
RMSSLAGSALMKAEGLEPNFQMVCRDRNRLAMMSDILGAYALGVRNMLCLSGDHQSFGNH
PEAKNVHDIDSMQLIALVKKMRDEEKFLNGEDIDVAPKMFIGAACNPFADPYEFRVHRLA
TKIAAGADFIQTQCIFNMDKFRDFMKQVVDKGLHERCYILAGVTPMKNAGMANFMSKYVP
GMDIPASLIKRLKGVDKRDQAEEGIRFALEQIEAFKEMQGVAGVHLMAIEWEHKVPEIAE
RAGVLPRP
>A0A4Q7MY84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kerstersia gyiorum|TrEMBL
MTQHTCSSSLAAQPAQPLLQDYSLEMTAREIRSLADIRTLATPGTRVNITFLPNEQDADR
LRAASLVHAQGLIPVPHLAARRIRSDTELRTYLARLREQAPARHTFVIAGDPPRPAGLYE
DALALIQSGLLAEYDIRHVSISGYPDGHPAIPADVLWRALHAKHRALALQGHDCEIITQF
GFEAAPILNWLERLRQEGIEVPVRIGVAGPVGVHKLLRYAAACGVGASAGILRKYGVSLG
RLFDTAGPGMLLQDLQTGLEPARHGVVRLHFFPFGDMEKTLRWILAQAA
>A0A4Q9WNN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus hominis|TrEMBL
MSRLLNHLKNNVLVADGAMGTILYSEGLDTCPEAYNLTHPNKVERIHRSYIEAGADVIQT
NTYGANFEKLKVFGLEHKVKEIHKAAVEIAKRAANKETFILGTVGGFRGIKQEDLSLSTI
QYHTDNQIDTLIEEGVDGLLFETYYDLDELTSVITATRQKYDIPIIAQLTASNTNYLVDG
TEINEALKHLIECGANVVGLNCHHGPHHMQRSFSHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAKYFGDVAQELINEGVRLIGGCCGTTPEHISYIKESVKHLKPIKNKKVIPIHRTI
NTNAKRTLKQNLTSKVKQRPTVIVELDTPKHLDTELFFENIGKLDEANIDAVTLADNSLA
TVRISNIAAASLIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLIGVSEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINVDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMSYFITQPVYSKEKIKEVYEATKHLDTPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYLITPFQRIDYSLELAAY
SKAITQNKEAIS
>A0A7X7SEW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp|TrEMBL
MNFDAVSGQASNGRVSNTPSVVDRLRASESGRVPFSVEFSPPRDEAAEARLWRAVRVFER
LGPAFVSMTYGAGGSTRDRTVRVTGQLAQETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWIKHPDGVEYAEELVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTKHLVSKLRAGAEYSITQIFFDVDQYLRLRDRVAAFDPIEGAKPIIPEIMPITSLRSV
RRMVELSGSKLPAALDRQLALAAGDGPEEDRAAVREIGIDLATTMCERLIAEGAPGLHFI
TLNFTRATAEVLERLGDKIGSAVSGPSELGSAGKEQPELGAVDVVVPVPVSGSAAPPDPG
IGQVPAAAAN
>A0A1I6IF05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] populeti|TrEMBL
MKIDSIFLKKKPVLSFEIFPPKRDTAIQSIDETLAILCELNPDFISVTFGAGGSVTNNLT
VELAKKIKQEYHIEPLVHLTCLNHSKAEIQQILQQLQEAEIENILALRGDRNPDVEPKQD
FCYASDLIQYIKEYGDFSISGACYPECHLESKNRIEDIHNLKKKVDSGANHLISQLFFDN
TIFYSYMENCKIAGIEVPVEAGIMPVVNKAQIERMVSLCGASLPEKFKRIMQKYEDKKEA
LFDAGMVYAINQIVDLLAHDVDGIHIFTMNNPVVAKRICDGIKNLV
>A0A847K3Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetaceae bacterium|TrEMBL
MPPRRPNLAPKFWQTVDDFMTYRPDFVSVTYGAGGKDFSTSHETITRLVRETPVKPIAHL
TCVGSPREELDQIIRDYLRVGVRTFLALRGDPPEDQPDWKPSAEHVSSAIELIHEIRRVE
EEECRAAPSTRLRNAIRPLTIAVATFPNGNAAAGTTVDQEIQRLREKQDAGADFAITQLF
WSADSYRTFLDLAERAGITIPIIPGILPGTSANRIRRTSELTGVPTPDELLTILDSAPNE
EEAYRRGVEWGARLIIDVLDAGAPGVHLYSFNQSGPALDLLEAAGVSSWYKTDV
>A0A6A2Z9Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hibiscus syriacus|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIAKNMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VLVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNNGVATPEAYQNDLAYLKR
KVDAGAVLIITQLFYDTDIFLKFVDGCRQIGIKCPIVPGIMPINNYKGFLRMTGFCKTKI
PDEITASLEPIKDNNVDSCPVVYAFVVRNIVDNLRILGGGVINWVARTANMDADALAKAG
IG
>A0A2X1T7E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morganella morganii|TrEMBL
MSFLHIDQHEALNQNLAELAGRVAVSFEFFPPGTPEMEKTLWQSIERLSVLKPKFVSVTY
GANSGERDRTHSVIKSIKEKTGLIAVPHLTCIDATRDELKTIAKDYWDNGIRHIVALRGD
LPDSSSKPDMYAADLVSLLKSVADFDISVAAYPEVHPEARSAQADLISLKKKIDAGADRA
ITQFFFDVSTYLRFRDRCAAAGIDVEIVPGILPVSNFKQLQRFAGMTNVRIPGWLGTMFE
GLDDDPESRKLVGASVAMEMVKLLSREGVKDFHFYTLNRAELTYAICHTLGVRPAACVA
>A0A354ISZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp|TrEMBL
METHNFSIEFFPPKTPEGVEKLRVTRRKLAELNPTYFSVTFGAGGSTQQGTLDTVLDIMA
DGHMAAPHLSCIGATRESIRSILQQFQQQGIRRLVALRGDLPSGYGGAGELRYANELVEF
IRQETGDWFHIEVAAYPEMHPQARSPQDDLQNFARKIGAGANAAITQYFYNADAYFQFVD
NTRKLGIEVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTDLAERLLAGGAPGLHFYSMNQAAATTAIWQRLTGTERQPSGN
>R7KAM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidaminococcus sp. CAG:917|TrEMBL
MKTCDLFKHKKLVLSAEVFPPKKTGNLEGVIRALKSIKSVGPDFVSVTYGAGGEGADTTA
DVASIAIDAFGINTVAHMTAVNMTVGKLESQVEMLSRKGIENILVLRGDVCPTSRFFDFH
HASDLAEYLSTRHPEFNLIGACYPEKHPEAKTLEEDIDNLKRKIDCGVTHLITQLFLDND
KFFRFLDLTSKKGINVPIEAGIMPMFSAKTLEHSVSLSDASVPAEFLKLKADNPDEKEFF
ERGISLAVKQIDSLIKGGAKGIHLYTMNKGEIAERILPKFKNDN
>A0A1H2SI54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseicitreum antarcticum|TrEMBL
MSTPRISFEFFPPKSLDASFRLWETVRMLAPLKPGFVSVTYGAGGTTRKLTHEAVTTIGK
QFGLNVAAHLTCVDASRAETMEIVDSYATAGVREIVALRGDAPKDQARFTPHPEGFANAL
ELIEALAETGKFTLRVGAYPEPHPEAADDMADVRWLKRKFAAGADNAITQFFFEADTFLR
FRDACVREGIDGSKIIPGIVPIENWQGIRKFATACNTSIPAWMDDAFDKAKRDGREDLLA
TAICTELCDKLLAEGVNDLHFYTLNRPHLTRDVCHALGVQPDTQLENVA
>A0A2A3XQZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glutamicibacter sp. BW78|TrEMBL
MPHDSNGAAPPALSFELYPPLDNSAVPKVVKTIGELAQARPDYVAVTYSGAPQRREATLE
LVGHLASNTRLRPLAHLTCVGESRASLTSLIERLIGSGVRGVLALRGDLPVDRATSRGDL
PFARHLIELIRDVESRHSAALCAGRLSVGVAAYPQRHPESPSFEHDVEVLLAKERSGADF
AISQVYFRPSDYARLLQSARDAGVRIPIVPGLIAFDSVRRLTRLSGLAGIEPDPVLAHRL
ETARDADERRRIGVEAAVDLGRNALNDGAPGLHLYTFNDHRGPLDVVGRLGLTGRFGDPA
PRPGRLTAVPA
>A0A1L7WVC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phialocephala subalpina|TrEMBL
MQYPLFTMEKITNKIAALPPGTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVT
WGAGGSTADKSLELAELCQRELGLTTCLHLTCTNMSKKLVDKALQDAKALGVRNILALRG
DPPRSEEYKERINGEGIDNIGEEEFEWAIDLVRYIRKTYGDYFCIGVAAYPEGHADEGHP
EGQSLEHDLPYLVQKTQAGADFIMTQLFFDVEAFDKFEKKLREHESGVFKTIPIIPGMMP
IQSYQMIKRTTKLSHARVPPNIMSRLDEVKGDDEMVKKVGVDIVSEIITHIQKEPAPGLR
GFHFYTLNLEKAVSFILERTNLIPAESEDEESAILDMTSPLQSLSVNGSHHPRSRRLSSI
GSDPHNRIIITGPRTSNPEYEATALEAAVPAEPINTRANTLAISEGEGALGREATWDDFP
NGRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGFPKSVGDITELFIKHIEGSLSAIPWS
EEGLNEETHTIKSQLLQLNKKGWWTVASQPAVNGVRSSDPIFGWGPKNGFVFQKAFVELF
LPSKDWTTLKARLTNLENKEVVSWYAANAKGDYLSSDSITINGVGTRGDEGGSTNAVTWG
AFPGKEIITPTIIEEVSFRAWAEEAFGIWEEWGRVYERGSESKKLIEGVREDFWLVNVIH
HGFVEGEGLWDLLLN
>A0A0D3FQL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryza barthii|TrEMBL
MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLK
QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNL
GLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLD
QLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWK
DEAFEIWSKGWACLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAFKEI
>A0A7W1BD23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTVRSESRLERLLHHGVFCVTAEVVPPRSADPEPVRAQARALVGYADAVNVTDNPTSSAH
MSPVAGAAFVSAAGLEPVAQITTRDRNRLGITSDLLAAWALGARNVLCLTGDPPGTGDHP
DATAVYDLTVLQLIGLAAGLREDGRLLSGVQIEQAPKYFIGVADVPLADPYEFARLEQKA
EAGADFVQSQIVFDTDAFGAWAEGARERGILERMFVLAGVAVPSGPRSARFMRDHLPGVS
VPDSVVARLEDAGPDAPDEGVRLTVEVIARLKAIRGIAGIHVMGLGHSGSVGRVIEAAGL
LPRPGLP
>A0A7K0A373|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVPPPPEAPPSFLDREGFHVLCEIEPPRRPDIEHVRNQIEVLNPVVDAFLIPDNHLGRAT
VSSVAVAHEVSYMGGLSIACINARDRNVLGFRRDLLTAAAYGVNHFLFVYGDPPKEGRRT
EDLTVRGMLQQVQSFGSGPLFSGFPDFRIGTVARPGRPLAWRTHAEFIFVQISFVTERLI
RWRDQVDYDGKMYAGVLVLTNKRMAQRINAALPDVRIPQSIIDKLDDDPQIGIDLAMDQI
QTLRESGAFDGVHLIPVSKFREISERLASGGHR
>A0A7K0LIT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
ELVDVVTRYRDAWIENILALGGDPPADSDQPPGELKYASELVDLIRGVGDFSIGVAAHPE
PHPHSPSIEEDRRRTAEKLSKADFAVTQFFFDARHYFDLVESLHELGVDKPVIAGIMPAT
SMRSITRMSELQGSEFPKDLAAKLEAAEPDGPEAVHRVGVEEATRLCRELLDGGAPGLHF
FTLNRSMATREIYEALGL
>A0A6L6AUF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSKLSDLLENTTELVYTAEFPAIDGGGMAQVQKYVDRLSPWFVAVNSTDNTAAHAHASNL
SVAIAMNDRGLEPIMQIVCRDKNRLAVQADMAGANLHGIHNIALLTGDDVTAGDEPETRR
VFDLDGPQAINVASVLNAGTYLSGRKLNPPPNFYISAVENPYAPPHNYRIERALKKQRAG
ARMLQLQIGYHPDRLENFCRGVAQSAPGLHLIPSIVLVKSARPLNFMNDKVPGIDVPRDV
IESVEKAEDQSEAAYQLALEQCKHALSLPAVRGLHITDFRHDDTLERLMNDLGRTPNQYA
>A0A7C6BK46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MSWLKQVLQSGHFAVTAEVGPPKGSDPQVIRKKCDLLKGFVDAVNITDNQTAIVRMSSFA
SCLIAQKQEIEPVMQMVTRDRNRIALQSDFLGACALGISNLLCLTGDHQSMGNHPQSKNV
YDIDSIQLLQIFKNMRDQKVFQNGEEVKGEINVFLGAGESPYADPLEFRALRLAKKIAAG
AEFIQTQAIFDVDIFTQWMEEVCCLGLHKKSFILAGVIPVKSAKALRYMKNEVPGVVIPD
NLIERMEAATDQKAEGVEVCIETIQKVAKIEGVSGVHIMAIAWESIVPEIVQRSGLLPRP
AKGEITSS
>A0A0J6FTZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus macyae|TrEMBL
MNLLKALENKVLIGDGAMGTLLYSYGIDQCFEELNLSHPEQVVNVHRAYVDAGSEVIQTN
TYGANYSKLARYGLEDLVKEINTEAVKLARMAAKESTYILGTIGGIRGINASSTPLDEVK
RSFREQLYCLLFEGVDGIMLETYYDLEELITVLEIARKHTDLPLIAQVSMHEPGVLQDGT
SLSSALNQLEAAGANVTGVNCRLGPYHMIQSLEQVPLSHSFLSAYPNASLPDYEDGRLTY
PTAPDYFKESAKALHQQGARLIGGCCGTTPEHIAAAASVLKDVKPITSKKITIKESDSLI
SETKNERIPHLHEIALNKKSTIVELDPPKKLSIDKYLKGAKALQEIGVDAITLADNSLAS
PRICNTAMASTIQSHYNARPLVHIACRDRNIIGLQSHLMGLHTLGINQVLAVTGDPTKIG
DFPGATSVYDVSSFDLIKLIKQFNEGISYSGKSLGIKTSFSIAGAFNPNIRHLDRAVSRL
EKKQQHGADYFISQPIFDDKQIVEVYEATKHLTCPIYIGIMPLTSSRNAEFLHNEVPGIK
LSDSIRSRMTKASDDQEAQLEGLAIAKYLIDTAFDLFNGIYLITPFLRYELTVELARYIK
EKTRLEDERKIRNGLHIV
>A0A7K0LX36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDRGAGSVTSAPTRLAGLARSRNQLATLASSRNRPIVTAECPSADGGTIDDLAARLATIA
PFVDAVNVTDNPAAHAHASNVSMAIALAGLGIEPIMQIVCRDKNRLAIQADIAGAAMFGI
VNFSALTGDDVTAGDEPEARRVFDLDGPQLVSVLAGMKAGTYLSGRKFTPTGDFFIGAVE
NPGAPPLDYRADRALLKVNAGAQMLQLQISYRPDQLEAFMSACVANGVAQRAIVLPSVCL
TKGARALSFMNDKVPGISVPAETIDRVANADDQAEEAYLLVRDLTVYALQLPGVAGIHIT
DFRHDGSVQRLTEELRIGPRFDSAIAETGTNPEHEERHAHSS
>A0A7K1AA03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTHISDLLAAGRTCSFEFFPPKTDDAARALEQTIAELEPLDPSFVSVTYGAGGSTRERTR
DVVINIERNIGITAMAHLTCVGHTRAQLDSLLDEYKAAGVSNILALAGDPIVDDNGVVAE
SEFEYAMELVELIKEKGGFSIGVAAHPEGHPRSADLYSDRRHLADKLNVADFAITQFFFE
AEPYLRLVEGLSAFGCDKPVLPGIMPVTNAAQVVRFAELAGAAFPPHLAARFDAIADDPD
AVRALGVELASELCQRLLDEGAPGLHFYTLNRSTATREIAANLGLGDASSAGE
>A0A7K1AZY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRDEGGTAARLSSRPHDTHQKARTTMSTSPMPTTTTAVQRQLVAEARYELIPLKNVDAQI
AHVPAGSSVSVTCSPAKGLQATLDLTAKILDQGYEAVPHFSARLTEDAAHVRRLAEFCRT
HALREVFLVAGDAPEPVGPYDGVVAFLRDFLDTDHGLQRIGITAYPDGHALIDRDVVHRA
LHDKQALLAEAGVPGFASTQMCFDVDQWKRWAAAERAAGFTLPLHLGVPGVIDRAKLLTM
GARLGIGSSMRFVKKNSGTIFKLFSPTGYDPSKLIAPMSKVARDLGIEGLHVFTFNNVEA
TAAWQRKQLAKLS
>A0A6I2ZF65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
QFFFEIDKWQAIVDKLAKAGSKLPVLAGILPITNVKQLNRMVELSGMKVPTAIADQFNKY
ADDLEATKEIGIEIATNLGAQLLKRGVPGLHFYTMNSAQSTVAIAKNLGLIK
>A0A3G2HLQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas monteilii|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDADGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DGDKHQEAMHWMRRQATPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETVQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQARIHTLDQWAPA
WRASWQMPGLPAVTFHPPQAGWRQGESRVDASLKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQRLWSTPVGAQVLHKVERAVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAAQTP
RRLSPQPTPRSQPES
>A0A7W0N2K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDRFSERLASGPPIVGDGGMGTLVSSAVARLRCPEEANLRAPESVLSLHLGFIRAGAELI
ETNTFGANRHKLRTHFLEDDVKSINEAGVKIARDAREVSGRDVFIAGSIGPLGEIGARRD
DREALFTEQAELLEGRGVDLFLVETFYELDELETAIRAVRSVSSLPIVALLTFDEDAHTL
GGVSAARAAAMLEEQDVAAIGANHGLGLQAALRALEQMSASGKPLAALPNVGLASLAGQR
VIFPHTTPEYFADFAAHAQELGARIIGGCCGTTPTQIAAVRDAVDQGRRPSAPLVVRERE
LVVASSQPEQETLLQQKLRTGAFVVSVEIDPPRGGQAQAMLDLARTLKESGHVDVVDVND
NPRARARMSGLMASATIERVAGIETIPHLTPRDSSIAGLESMLLGAHAEGIRNVLAVTGD
PPEAGDYPGSGGVYEVDSIGLSKIITHMNAGEDFNGREIDAPTSFFLGVAVNPAADDPGY
ELERFEQKLEAGAKFAMTQVLFDFAYLDDFIARLGRPCPIPLLIGIFYVKSYQLALRLHN
EVPGIVVPDHVQTRLREAGPNAAEAGLAIAQGLLEESRERAAGAYVIPPFRQPLAALELF
S
>A0A7K0PM79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSKLRDLLTQTKDVVYTAEFPIIDGGGMEQVKKNVDRLAPWFVAVNATDNTAAHAHASNV
SVAIAMKQHGLEPIMQIVCRDKNRLAIQADMAGANLHGIENIALLTGDDVTAGDEPETRR
VFDLDGPQAINVASILNAGTYLSGRKLNPAPNFFICSVENPFAPPHDYRIERALKKHRAG
AQMIQLQIGYHPDRLEKFCAGVAATVPDLAIIPSVVLIKSAKPLSFMNDKVPGISVPQEV
IDRVAQSADQSEAAYQLALEQCQHALALPGVRGLHITDFRHDDTLERLMRDLGRTPNQYT
>A0A8F7N144|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VKFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>K8E355|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carnobacterium maltaromaticum LMA28|TrEMBL
MGLKEVLGTKLLIADGAMGTLLYQYGIDRSHEELNCSHPEAILKIHQDYLAAGADIIQTN
TYGANYIKLARYGLEDQVQKINRAGITLAKEARGDKEAFILGTIGGIYGAVDTKIHDPGM
EEISRSFKEQLYCLLLGGVDGILLETYYDLNELKTVLAIAREATDIPIIANVSIHEVGIL
ANGQSLATALEELADLGANVVGTNCLLGPHFMAQSFESVPLIPGKVLAAYPNASFPTMEN
GRIVYQKETDYFKLFGELFRKEGVGLIGGCCGTTPEHIAAYRKGLTTLDLVTQKKVKALT
TYRFQAKQETGKERLLDKVQREFTVLVELDPPRTFNTTAFFKGAARLKEVGVDAITLSDN
SLASARISNMALSAMLKYEYDIQPLVHLTTRDHNLIGLNSQIMGFHKLGIHDVLAVTGDP
AKVGDFPGASSVFDVSSFELIKLIKNFNQGIAYTGKNLREKTNFQVAAAFNPNIPRLERA
GCLLKKKQEAGADYFITQPIFDSEKVKILKEVMKTAGVTIPIFIGVIPLVSSRNAEFLHN
EVPGILLTDETRERMRMAEEEGRGLEVGMTIAKELIDEICQEFNGIYLMTPFMNYEISAE
LCEYIQAKKQQEKSICSCGQVHSQ
>A0A7L0F4P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corythaixoides concolor|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGEK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETVLHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEAGGFNYAADL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6I2XZM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRKEGSFVGGPVSAAPGPSLGEVLASGERSFSFELFPPKTDDGERALWQTIRDLEALNPT
LISVTYGAGGSTRDRTVRIVAGIAAEPALTPLAHLTCVGASRDEVRSVIDEFAAAGVRAI
LALRGDPPGGPGAPWAQHPDGFAHADELVELIASMGGFSVGVAAFPEGHPESPDLDADAL
VLARKQDAGAEFAITQFFFEARDYERLVSDARRHGCTMPILPGLLPVTNVAQIERFAALS
GAAFPAELAARFALVKDDPDAVHALGVEVAAALAQELLDLGAPGLHFYTLNRSTSTREVY
EALGLGSD
>A0A7W0UL95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNDRLSLEKPGLSHGKEDPSPLLPSEVSRNLLVELLKGSAFEIFPLPGVEGHLDSLPEGT
HVTITCSPTQGIAETLSLTEKLRSGGLRVVPHISARLVRDDAHLQALIERLAELEVAHLF
VIGGDVTQSAGKFPSTLSLLRALADKGHPFESIGVAGYPEGHPFLDDDSLNEALKAKEPF
ANYLVTQMCFDPGAIISWVEAIRRQGIRLPVYIGLPGAVLARRLLR
>A0A371JNP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda nanhaiensis|TrEMBL
MKVTEHIKKAKGETLFTFEIIPPVKGKNIKELYDNIDPLMEFKPPFIDVTTSREEYIYID
RDGLLDKKLTRMRPGTLGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGINNV
MALRGDAMKEEKYFEPTKGGHKYASDLVGQIRNLNQGNYLHEVIETDNCPDFCVGVAGYP
EKHMEAPSIKSDLKRLKHKVDLGANYVVTQMFFDNNKFFEFVDEARKMGIDVPIIPGIKP
IAVKRHLQLLPQVFRVDIPQDLVDAVEACKNNKEVRQVGVEWCIQQSKELKEAGVPVLHY
YSMGKSDNIKAIAQEVF
>A0A0M9CU22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. XY332|TrEMBL
MALGTASTRTDRARTVRDLLASGSPSYSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSV
TYGAGGSTRGGTVKATQQIAADTTLTPVAHLTAVDHSIAELRNVIGQFADAGIRNMLAVR
GDPPGDPMGPWLAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSAGKAGCETPIIPEVMPVVGIKQLDRLPQLSNAVF
PAAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQRA
>A0A330HKL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium hawassense|TrEMBL
MTARQRDENPAGIHLPLDSLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFRTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWQREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A3N5TQL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSGSSSRLEALARSRRFCVTSEVVPPRSASAEPVERQARELVGYADAVNVTDNPTASAHM
SPVAGAAIVARSGIEPTLQLTVRDRNRLAIAADVLGAWALGARNLLCLTGDPLSVGDQPD
AAAVHDIGVLDLVALGRTLREDGRLPSGAEIEDAPRYFVGVADSPLAET
>E3I490|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodomicrobium vannielii (strain ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG 4299)|TrEMBL
MTEAGTQRRAHAPISVSFEFFPPKTDAMEASLWQAIRKLEPLAPEFVSVTYGAGGSTRER
THSTVSRILAETSLKPAAHLTCVAATKDEVDAVVRDYWDVGVRHIVALRGDPPAGAGTAY
AAHPGGYQSSADLVAGLKTIGDFEVSVSAYPEKHPESGSFDVDLDVLQAKVDAGATRAIT
QFFFDNDHYWRYLDRVRARGINIPIVPGQIPIHNFKQIAGFAARCGATMPASTGARFEGL
ADDPETTQLVAAAVAAEQVRDLVKGGVTEFHFYTLNRAPLVNAICHTLGIKPHAPAASAV
NA
>A0A538E4V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MLTHPRYEVFPVEGIADDVVAHVPTEIKVAVTSSPTRGIDATLRLCEELASAGFQVALHL
AARLVRDEEHLRETLDRLGVIGVRDVFVIAGDVDLPAGKFDGATALLAAIADLGHQLDEV
GISGYPESHPFISDETTIQVMFDKEPFATYIVSQLCLDAGVIAWWIGAVRARGVRLPIHI
GIPGPVPSRKLLRIATRIGVGESTRFVRNHGGLLTRLFLRGRYGPGSLIERLTPLLGNPG
NGIAGFHVYTFNELATTESWRREALRRLETVQAAELGRRT
>A0A523VJX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAKKKLHSGSNLEKVLNSGEFAVTAELGPPKGADAKVVLDKAAILKGEADAVNITDCQTA
IVRMSSIAASNLIKDKGLEPIVQMTCRDRNRIGIQSDLLGAWGLGLKNLLCLTGDHQKFG
NHPESKNVFDMDSIQLVQMVRNMRDKKQFLNGEEIEVAPKFFIGAVENPFADPFEYRALR
LMKKIEAGADFFQTQIIYNVEKFKKWMAEVRKLGGHKKAFILAGVAPLKSAGMAKYMKKF
VPGMDVPDKVIKRMEKAKDPKDEGIKVCVDIIKEVRKIQGIAGVHIMAIEWEEAVPTIIE
RAELGERPKVN
>E8UWM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter brockii subsp. finnii (strain ATCC 43586 / DSM 3389 / AKO-1)|TrEMBL
MLKNENLCTKLKKRKFVVTAEISTPKGVDITKTIEEARKLKGIVDALNITDCPMANMRMS
PIAVAHLLQDHLNIEAIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDEPSRGDTPQ
AKGVYDVDSVGLLKIISAFNRGYDYNGNKLDSPTEFCAGTTANPNDLRDEALEKLKVKIE
AGAEFIQTQPVYDEEILFKFIEKIKNFNVPLLIGILPLKSYKMAVNLNEKVPGIDIPEKV
LERLKDGGREEGINIAVEFIKRIRSEVAGIHIMPLGSTNVVLEIISRVDDLVCDFAENNV
QMN
>A0A2E8LW51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MREAQRALETPLFSGLSGDIEVSFEFFPPKNERMNETLWRSVETLAPLGPRFASVTYGAG
GSTRERTHQQVVRIQKEAHIPAAAHLTCVEATREQVDEVARHYWDEGIRHIVALRGDPPD
GANKYTPHPGGYANAVELIAGLKKVADFEISVAAYPEVHPDSPDAQADIDNLKAKFDAGA
TRAITQFFFDPQCFFEFRDKAAAAGIAGEIVPGIMPVLSFAAVQRMSGLCGTAIPHWMEG
LFDGLDDRPEARKLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKV
>A0A2Z5SVX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|cyanobacterium endosymbiont of Rhopalodia gibberula|TrEMBL
MISRFRQAVQNKEFLITAEVTPPKGGNPVRMVEMAQKLKGRVHGVNVTDGSRAVLRMSSI
AASALLLQYGVEPICQMACRDRNVIGLQADLMGAYALGLRNVLALTGDPVNAGDHKKAKA
VFELESVRLLKMIDNLNRGVDFNYQSLPDDPLDLFAGAAVDPQCPSWSGLQRRFERKLAA
GAQFFQSQLITDFEQLDKFMQQIAAGTGKPILAGIFLLKSAKNANFINRNVPGVKIPETT
IQRLANADDALQEGVKIAAEQVQLARELCQGVHVMAVKREDLIPKILNLAGVSPISLEQA
VIN
>A0A369QYU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum sp. 12E13|TrEMBL
MDVARLTQPTDALLQRLFESNGAVPLSFELFPPRTEARHAALRETVKRLAPVAEDGFSVT
MGAGGTTRTGTHATAVEVAHLGERPVTAHLTALGLTEADALEAAEELWEAGITRILALRG
DRPRATAGPLPPGFVHSSELVAALAARHPFEIAVAAYPEKHPEAETLSEDIDYLKEKVDA
GASRAYCQFVLDPAAYGRFLEACAQHGIDVPIIPGLMPLEGWTRLRSFARANGARVPDWL
ERLFVQGEDTPELMPHLAAVATLEQARRLIAFGAPALHVYCMNRWPLALALARLLGHR
>A0A2T0T384|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma oryzae|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PMPDGSIQKIVTRKRPGTVGICSAILHRFGVDPVPHVLCGGFSRDETEDFLIDLQYIGID
NVLVLRGDPAKPFSTFKAKENGYSYASELVEQVADMNRGHYLHEEDTALAPSNFCIGVAA
YPEKHFEALDHDTDFQYLKQKIDKGADYIVTQMFFDNQKYFDFVDRCRQAGITVPIVPGL
KPLSTRKQLQILPKLFHLEMPADLVKAVEQCENDQQARQVGVEWGIQQCRELMAAGAPVM
HFYTMGKADNVMKIAKAVF
>A0A1L8CLZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariprofundus micogutta|TrEMBL
MKLSDILNSADKPLFSCEFFPPRTDKGEENLWSCLKELQAINPAYISVTYGAGGTTQDRT
KGIVSRIKDKTGLSPVAHLTCVGASKTQLGELLAEYKAAGINNILALRGDAPEGMNSFEA
VAGGFSYATDLIAFLREQGDFSIACATYPEGHPESKGGVADDIRYLKMKQDNGADCAITQ
YFFDNDTFFRFRDQCDAAGITLPIIPGIMPVGNFEQIVRFSSMCGAVIPAWLHEKMTPIQ
HDLDAVKALGIELAAKQCRELLEADAPGLHIYTLNKSEATIAIHQQIKDLL
>A0A4V2P4J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. KM273126|TrEMBL
MPFKSAEEKVLAHVPTDVALTVTTTEAKGIGPTIALAASLTGHGYRAAPHIAARLVRDQA
HLADIVEQLRDSGIDRLFCIGGDAAEPAGDFPDALSLFQGLQTIGHSFTSVGIGGYPEGH
GLIDDELIEQALEAKAPYATQIITQLCFDAATTIRWARTVRARGVTLPIRVGIPGAISRQ
KLIRVSAGLGLGQSARFLKKQQNMFWRFFLPGGYSPNKLIEKLTPAFAQEDNNLQGFHVF
TFNDLESTEAWRKAWLARLS
>A0A4Y7TSW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprinellus micaceus|TrEMBL
MRISQKIEQSAKEGKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPREKVDIALKDAKEAGCRNILALRGDPPSGKDE
WEAVEDGFVHGIDLVRHIRKHYGDYFDIAVAGFPQHMELPEKERDQEIQWLKEKIDAGVN
FIFTQMFYDVDLFISWVKAVRAAGITVPIVPGINPIQTWNGFIKATSLSQTAIPQHLMNV
LEPVKNDDEKVRALGIKVVAEMCRKILDSGLGIKGLHFYTMNLERGTKMLLEELNLVPRI
ETIKPLPWRQSLTPNRRSESIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGISIKQTKDNALQLWGHPTSFPDIADLFAKFCAGQLVALPWSDSAPSQETGIISNQLA
KMNRLGFLTINSQPAVNGVRSDDKIFGWGPSNGYVYQKAYLEFFVHPDLLQLLLKHIERD
SNITYYAINKRGDLRTNTHSEGPKRCNLGFMAWKDEAYELGSQWAKLYETGSPSHKLIDE
VMETYSLVNVVHNDFHQPQGIFEPFWKAGEEWEAVKGPKVNGDASVTNGSAIINGVH
>G2G7Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces zinciresistens K42|TrEMBL
MALGTASVRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGDWVRHPQGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADRDLDVRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCDTPIIPEIMPIASVRTLERIPSLTNAAF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEEVPGLHFITLNNSTATLEIYENLG
LHHPPAGLDRSS
>A0A1F9B135|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_42_7|TrEMBL
LSSKKFTITAEICPPKGTDISDFLKKARLLKNKIAAANVTDNQRAVMRLSSLACSVLLLK
EGIDPVFQMTCRDRNRIAIQSDIMGAWALGVKNILALSGDHVSFGDHRDAKAVFDLDSVQ
LVQVISKLNSGTNMKDTPLKGGTDFFIGAVVAPEAEPWESEMIKFEKKIEAGAKFFQTQA
VYDMEKFHRFYEYAKKFDVKILAGILLLKSAKMAHFLNNNVPGVTVPKHLIDELEKAPDQ
LMRGIEIAAQQVKELRAFCDGAHIMAIGQEESVARIIETAG
>A0A0E2LCZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli (strain UMEA 3162-1)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8I1ZDQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQTGHTDR
VYLRCALQILICKHLGFAGIHLSACHKQEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKKTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A8C7JS58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus kisutch|TrEMBL
LLFRRHSRTGVGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTESGDHWFSLEFF
PPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESI
LHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKHIRCE
FDDYFDICVAGYPTGHPEADSYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVRDCRA
IGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIRNYGIEQTVGM
CRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPI
FWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEEL
TSEQSVYKVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMMDELDKVNRRGVLTINSQ
PTINGKPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPRVNYHIVNVHG
QNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPS
RMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPDEQPTEQPVEQPAEESPV
EDQSPK
>A0A2G1TLG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFELFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQAGHTDR
IYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQSEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A7X9TY45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SWRI 103|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIQRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGADSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISMMCEKLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7V9CFI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MLTFDKKLELLRISSFLGTAPPEMLSEIAAAAHEESFDKGRFIYAKNDPAAYFYFLVQGR
IGHPEVQAGDKGSLAYRADAPGQLFGFAAAVQGQPLRVISARCELPTTVLAVDGQWFQKL
CTRYGKEGEERLRELVRAHAGYERTILGKPGWLSVRNAGKKYGSKADGAVALDDCSIEVR
PGEFSAVLGPRGSGKSTLARAIAGLEMLDDGVMYLDGDVINRPGNKPKPRRICLHQRNRL
RPAKTLARNLQRATDGESAGSPVWELLRQFGLSEFADRLTRVLPASIRYRAEIIATFLSD
ADVIIFDEPFALGLERTELHRLLLELHRHARKTVLFMTEDVEESVHLADRVQIMVDGRIR
RSVLIDLPLLRRPDLLVTPELLRLRQKVFEALHARPEIADQEVPGPLPRRADEKVAVELS
FPAPDRALPPPNAIRQALCSGKFFWTIEFIPSVDKILRDELHKIGGITEVLAEDPLLAGF
AVTDRVVSERDPDPVAAASHLLQYSGKQPLVHFSGKGRESDELDGFVERMQEDGLENALF
LTGDRLKRELPGQRLRYLESVPAIERAKQLNPRLWAGAALNPFKYREEDAMAQYLKLGKK
VGAGADFVITQIGFDMHKYEEALDWMDMRNYRVPLVANVMPMPPARARYIRHHQLAGVTV
TDSVMALLEEEERVFADKGASRAMRRLALQIVGLKLFGYSGIQVTGLHAIEKMSALKTQV
AELSELCGERDTWSKAWEESFTLPEGGHADPAPHHPWYLDRSRSFHSSRRSRREYRHRAM
NGIHDFLFANGLGAKFLRPVLKPIRRHSKVDRLLTLMERAIKGPLFGCETCGMCRLAATQ
YICPETCPKGLANGPCGGTTENLCEFRDRECIHSAKYRIARDAGVLHELESWLVPAVPKD
VRNTCSWPSYLRGEGPGIRVIKFSCPRADD
>A0A7Y3KGK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eremiobacteraeota bacterium|TrEMBL
MDIAEQLASRRPFFSFEFFPPKDDAGREALFATIASLEALGPAFVSITYGAGGSTRARTV
ELAKQIAERTGITVLAHVTAYGQSRAELRALFDELSRAGIRNVLALRG
>A0A432QUM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurobacterium sp|TrEMBL
MTFGEKLKAGKFLITAEVAPPRGTEWKDVVRGIEPLKGKVDAFNVTDCQRSMVRMSPLAM
SKLLLDSGFDPILQLTCRDRNRIALQADLLGAAALGIRNICLMTGDFTTLGDQKDAKPVF
DLDSVQLIETATRLTEGYLLNGKELKGAPRFCIGAVFNPFAGPFELQVMKLEKKIKAGAL
FVQTQPIYDARIAEEVNDLVCELGAVPIIGLLPIKSLKMANFMKKLNPTSVPDSLIEGLE
RSENPAKYGWDYTIDLAHAIAEFGKGIHFMLVGKTEELASFIDYLKNHKKYNHKF
>G7MGV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macaca mulatta|TrEMBL
MDHRKARVLPAGHYCPSLGIWASKAGSVRFSVPPSISRNLAMVNEARGNDSLNPCLEGSA
SSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDALELLNRPTQNERETEAP
>A0A242H571|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus sp. 12C11_DIV0727|TrEMBL
MRTDTLFKEKTVFSYEIFPPRRTAPIDTIYHTLDRLKGQQPDFISVTLGAGGTAANLSTA
DIAQKIQDEQFLPSVAHLPAVNFSKDEIVVILEELKQKKVENILALRGDLLPDREPKKDF
CYANDLVSFIQEQGDFNIIGACYPETHGDSENSVTDIRNLKRKVDAGTNQLITQLFFDNN
YFYTFKEKCDIAAIEVPIQAGIMPVVNKKQIERMVKMSNVTLPTKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVTQGTDGIHLYTMNNPYVAQKIREATRSLFDA
>A0A373BK40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium AM23-16LB|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGKDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKAAEI
>W1UIC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. DORA_10|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKHIHQATHALFNHQSLG
>A0A0X3TZL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria marisrubri|TrEMBL
MTAPEISFEFFPPQSLEASFRLWDTVQALAPLAPRFVSVTYGAGGTTRELTREAVATLHD
HSGLNVAAHLTCVRATREETLAIADEFAQAGVTDIVALRGDPPKGEGRFRPHPGGFANSV
ELIEALADTGKFSIRVGAYPDIHPEAASAAADIDWLKAKLDAGADEALTQFFFEAETFFR
FRDACAKAGIDKPITPGILPIENWKGARNFAKRCGTRIPAWVEQAFEKAVRDDRQDLLAT
AICTELCSELIEGGVDKLHFYTLNRPELTRDVCHALGVAPKVSLQNVA
>A0A1N6YND8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudacidovorax sp. RU35E|TrEMBL
MRLPISFEFFPPKTPEGAVKLRAVRAQLRARAPQFCSVTYGAGGSTQAGTFATVKELLEE
GTDAASHFSCIGATRETVREQLHQLKAMGVRRLVALRGDLPSGYGIGGEFQYASDLVAFI
RTETGRDFHLEVACYPEVHPQARTPQADMQAFATKVRAGADSAITQYFFTPEAYFRFVDE
ARAAGADVPIVPGIMPITSSTQLMRFSDACGAEIPRWVRLRLQSFGDDTASIKAFGLDVV
AALCERLVAGGAPALHFYTMNQAAPTLALLDRLGLGE
>A0A8G1NRD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDAXRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPXMYAADLVXLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A8G1P405|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania gelatinilytica|TrEMBL
MSPTLDQMREAQRALETPLFSGLPGDIEVSFEFFPPKTEKMAETLWQSVETLKPLDPRFL
SVTYGAGGSTRERTHEAVRRIVGETDIPAAAHLTCVDATREEVDEVAREYWEEGVRHIVA
LRGDAPDGSGTYTPHPGGYENAADLIAGLKKVADFEISVAAYPEVHPDSPDRQADLDNLK
RKFDAGATRAITQFFFDPECFFDFRDKAAAAGIEGEIVPGIMPVLSFAAVQRMSGLCGTA
IPDWMEGLFDGLDERPEARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRPKA
>A0A7X0JLG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium soli|TrEMBL
MALLNLFRGKQEDKAPKPASLKSLVEGYSIEVMPRTAAKIDDFTTLLPKNTRVYIAHIDG
TPIDDMVRTAKRLRENGFEVMPHIPARSIESRAMLEDWVSRYHNEAGVDQALVLGGGLSR
PAGALDSSLQLIETGVFDRHGFKRLHVAGHPEGNRDIDLDGTTKLVDEALKFKQIYSEST
DAKLAIVTQFAFDSRPVILWAERIATTGVRMPIHLGVAGPTKLQTLIKFALTCGVGPSIS
VIQKRAMDISKLLVPYEPTEFLTEIADYKARNPQSLIEQIHVFPLGGIRASAEWMNERQP
APGVIRAI
>A0A413H631|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides stercorirosoris|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAGAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESAFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKITKTPFSYGVACYP
EKHEEAPNIDTDIYWLKQKMEAGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELACEAMKCKTDEEARQVGIEWCVQQCKELMEHGVPSIHF
YSIGAVDSIKEVAKQVY
>A0A422ZJ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae|TrEMBL
PPRTSEMEQTLWKSIDRLSSLKPKFVSVTYGANSGERDRTHSIIKGIKERTGLEAAPHLT
CIDATRDELRTIAQDYWNNGIRHIVALRGDLPPGSGKPEMYAADLVSLLKEVGDFDISVA
AYPEVHPEAKSAQADLLNLKRKVEAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPG
ILPVSNFKQAKKFADMTNVRIPVWMSKMFEGLDNDAETRQLVGANIAMDMVKILSREGVK
DFHFYTLNRAEMSYAICHTLGVRPA
>A0A1W9PT16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolinea sp. 4484_236|TrEMBL
MSLFSPPRYQAPFKPYRRDDLTPFIKVFTAAEGLIKGALFGCRMCGNCILQETAFICPMT
CPKGLRNGLCGGATPEACEVDPSRPCTWYKIYERAEKMGREDMLLENNAPLDGDRVGRET
WLDVVQMWRDREDSPKFTEYFSNREKFDEDWENFFYDVRQPDWWKGDKEYHPPAYEEPIS
LLEANLRTGEFTCTGEIAPPLSVSKTIINKKAGWLNGYVAAANFTDNASASARMGSMASS
LLCLESESGLEPVMQLQARDRTRVVIESDVMGAAGLGIRNILCLSGDHHRFGPGPVSKPD
QFDMDAVQMLWMLRRMRDDGKYIDGRNIKFRPQLFLGAAGSPFGAPPKYEAIRAEKKINA
GAQFIQTQPIFDYNGFMEWVEALDKRNLLDKVYILAGMIPLKSARAAHFMVDVPGVSIPP
EIIKRMDDAGDKDGQSEEGVAIALEMIEKLKNTSGISGIHFMAVHWEAIIPRLMDESGLP
KPTVTSLGKTEN
>A0A7X0QLM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas sp. MC1825|TrEMBL
MTPISFEFYPPKNDEQRAQLERTAARLAPHAPEYVSCTFGAGGSTLSYTGDTIRGLLAQG
FDAAPHLSCVGGTREEIAALLVEYRDAGCRRIVALRGDLPSGMGHPGDLRYASDLVEFIR
AEHGDHFRVDVACYPETHPQAEDALADLRHFKAKVDAGADGAISQYFYNADAYFRFVDAV
RRLGVEVPVAAGIMPISNFSQLRRFSESCGAEIPRWLAKRMAAYGDDAESVRALGADFVA
DLCRRLVDGGAPSLHFYTLNLARPTLAVLDAMA
>A0A8J7EBL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nodosilinea sp. LEGE 07088|TrEMBL
MGYRLRTAAKASQFLVTAEVMPPKGGNPDHMLAMGQLLKERVHAVNVTDGSRAVMRMSSW
AAALLLQQQGVEAVCQVACRDRNRIALQADLMGVHALGLRNILALTGDPVKAGDHPEARS
VFDLESVRLLKLLEKLNYGVDSHDKPLADGALDLFAGAAIDPQSPSWSGLQRRFEAKVKA
GAQFFQSQLITDFDRLGKFMDQVAASYHRPVLAGIFLLKSAKNAQFINRNVPGAQIPEAI
VERLAAARDPLQEGVQIAAEQVQVARQLCQGVHLMAVRREDLIPQILDLGGIAPLETALS
HPSHS
>A0A2X2C6H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus mirabilis|TrEMBL
MENTLWQSLARLNTLKPSFVSVTYGANSGERDRTHAIIKDIKERTGLEAAPHLTCIDACR
EELQHIAQDYWQSGIRHIVALRGDLPDNSQKPDMYAVDLVHLLKDVGDFDISVAAYPEVH
PEAKSAQADLINLKKKVDAGANRAITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTN
FKQLKRFAGLTNVKIPGWMHKMFDGLDNDPETRALVGASIAIDMVKILSREGVKDFHFYT
LNRSELTYAICHTLGVRPQLAKV
>A0A4V5PT86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter capsulatus|TrEMBL
MTTPKVSFEFFPPQTLDASFRLWETAQVLAPLKPGFVSVTYGAGGTTRKLTHEAVAAIHK
NYGLNVAAHLTCVDATKAETQEIIDAYAEAGVTEIVALRGDPPKGAARFTPHAEGFASSV
DLIEWLAKDGRFTLRCGAYPEPHPEAADTLADVRWLKRKCEAGATSAITQFFFEAETFFR
FRDACVKEGITAKIIPGILPIQSWKGAKGFAQRCGTSIPAWVEEAFDHAIRDDREQLLAT
ALCTELCDNLIAGGVEDLHFYTLNRPQMTRDVCHALGVNPDVVLENVA
>A0A2R8B295|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Defluviimonas aquaemixtae|TrEMBL
MSVSADYSDPVPVYAPPPEGHVSHSRLERVLRAGRFAVTAELNPPDSADPADVFEAAQPL
GEVADAINATDASGANCHMSSIGISALLTRAGYSTVYQISCRDRNRIAIQGDVLGAAAMG
VANCLCLTGDGVGVGDQPGAKPVFDFDSLTLLRTIRTMRDQGMFLSGRKITRPPQMFLGA
AENPCIPPYEWRPERLAKKVEAGAEFIQTNYIYDIPLFEKFMVRVRDLGLDKNVYILAGV
GPLASAKAARWMRSNVPGIHVPDALIERMEKAEKPGAEGKKICIELIQQIREIKGVAGVH
VMAYRREHQVSEIILESGVLEGRQPRRRSERR
>A0A0F6YJN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sandaracinus amylolyticus|TrEMBL
MVFDGAMGTQIYERGVLYTQNFDQLCVTRADLVKSVHAGYLAAGAEVLQTNTFGANRYRL
ALHNLEGQLDAINRAGVRIAREVAGDQAWVAGSIGPSGKILKSVRAGELDELREAFRDQA
AVLLDEGVDALILETFRQPEEVRLAIEGAKLALDAAPEAKRGPIIASVSFDSFGTMADGT
GPEEMAQRLVAWGADVIGVNCADGPAGVYETATKMVGAGRPIVAQPNAGLPRRVEGRFAY
MATPDYFLVFARRMLKAGVRGIGGCCGTTPEHVRQMAAAARMVGATGEAGGPEIVSLAGA
HELREATPQVAPGVTRISLAEKGPLGAKIGKKFVVSVEVNPPAGLSPQKALDAARMLRDG
GVDVINVADGARATARMGNFALCHRIQDELGMPAIMHVTTRDRNLLGLVAHLLGCHELGL
TNLVVITGDPPKMGDFPDATPVYDVDSVGLLRLIDGMNRGFDPGGKPLGAATRFLLATGA
EPAAKDYQRELERLKKKREAGAEVVMTQPVYDPDVLDRFLRDVAPLDMPVLVGLLPLASY
RNAEFLHNEVPGMSVPHEIRERMRKAGAGEEARREGVAIAREMLLAVKSRVAGAYIMPPL
GRYELALRVIDGVV
>A0A7J9YIS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola sp|TrEMBL
MTRINYEGFNPAKDPGVELLSMPRWELAPVKEPLLAAEVLPPGTEVTMSCFASSEGFETT
IRLTRRIIEHGHRVTPHLPARSIGSSNHLAELLSALKESNVTNIFVVAGNAKKQVGPYGG
AFDIMEMVAAAGFTIGIAAYPEGHPYLSAAEAIDLLRHKQRYASYLVTQTCFDHRLLRDW
LMKCRQHGVYLPVHIGVAGVVQRKELFRMAAWMGVGNSMKFIKRQHKLSARLVTPGAYNA
TSLLNGLLDCVYDNNLGRVGLHLNTFNQVKKTYDWWKGYVSSIDLGIESNPSD
>A0A8H8D343|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Histoplasma ohiense|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNILALRGDPPREKEK
WEAIEGGFRYAKDLVKHIRDKYGNHFDIGVAGYPEGCDDQDDPDLLMQHLKEKVDAGGTF
IITQMFYDVDNFLAWVNKCRENGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEAL
EPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQATKMVLGELELIPSHKTP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGQPKSLKELSEIFVRFLNGNLDRLPWSEGAVTEETDVIKLDLLD
LNRRGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNP
DLTYYCVNKIGELRTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHVASSPSRRIIQQVMDSWYLVNIVNNDFHKTHDIFNIFKDLKVENLNEQVEPIAPAAE
LVDNTRENSHDPQKQVNGS
>A9FZY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum (strain So ce56)|TrEMBL
MRTMSRTRPEAPFLDALRRSILVFDGAMGSLLYERGVFVTQNFEQLNVARPDLVKKIHAE
YVAAGANVIETNTFGANRFRLERYGLVNEVRNFNLAGARLAREIAGGDAYVAGSIGPTGL
VPGVATRDDLAAASATFAEQAGALAEGGADLLILETFRHLDEIKLAIDAARSAAPGLPVL
ASMTFDTSGVAADGSEPERVARTLRDWGVELLGVNCGDGPQLSLAMAERMATAGLPLCVQ
PNAGLPRTVDGRQLYMATPEYFDVFARRMIQAGAAMIGGCCGTTPEHVRWMAKSARMLRG
GAAPEAAARPHVTMDAPTGLEPTPLGERSPLAAKIAAGKFVVSVEVNPAPGLNPESALSA
AKMLIDSGVDVVNVADGPRATARMTNLAFCSLLVQRYGIEPILHVCGRDRNLIGQMAHLL
GAHAIGIKNLVIITGDPPKVGDYPEATAVYDLDSIGLLHMASTMNRGLDPAGKPIPGGKT
SFLLATGLEPGAQDLDKEIARLERKRAAGADIIMTQPVFHQDLLEKVLRRIEHLGMPVLV
GVLPLVSHKNAEFLHNEVPGMQIPEEIRERMRKVPAGPEARKEGVKIAREMLFSVRDRVQ
GAYLMPPLGKYELALEVLDGLKTG
>A0A7V8RDE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas ursincola|TrEMBL
MTLSLKQLAEAREALGAPLFAGLAGDVEVSFEFFPPKTEKMEATLWDTLTTLAPLGPKFV
SVTYGAGGSTRERTHATVARIASETAIPAAAHLTCVDASRDEIDSIAQSYWDAGVRHIVA
LRGDPPRMGEKFVAHPRGYANAAELVKGLKQVAPFEISVAAYPETHPDADCADSDIDNLK
RKLDAGADQAITQFFFSPEAFFRFRDAYTRAGITAPILPGILPVSNVATTRKIAGACGTE
IPQWMNDLFEGLDDHPTTRQLVAATVAAEMCRRLYSGGVRHFHFYTLNRAELSFAICHLL
GLRAPKVAAAPVLQENAA
>A0A3L6EMU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zea mays|TrEMBL
MAEGGGERASSELGERDCRIGWSRWREETPLGFEPDNVCVETMMHLTCTNMPVEKIDHAL
ETIKFNGIQNVLALRGDHPHGQDKFVQVEGRFACALDLVQHIRSKYGDYFGITVAGYPEA
HPDAIQGEGGATLEAYSNDLAYLKRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCP
IVPGIMPINNYKGFMRMTGFCKTKIPSEITAALDPIKDNEEAVRAYGIHLGTEMCKKIIA
SGIKTLHLYTLNVDKSALGISMFTRPREGGKKLQEEWAVPLKSVEGISERFTNFCQVSRE
THKQPMVRTGWSSTRDKDY
>A0A7Y4EHS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. RE86|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELIQIADDYWANGIQSIVALRGD
IPPGGGAPEMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRSVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAQQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>D8G7P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kamptonema sp. PCC 6506|TrEMBL
MNRFRTACKTPGEFIITAEVTPPKGGDPTHMIKMAQTLKDRVHAVNITDGSRAVLRMCPL
AASVILLQHEIEPICQVACRDRNQIGIQADLMGAHALGIRNILALTGDPVKAGDHPKAKS
VFDLEAVRLLQLIQKMNCGTDWNDKPLTDGITELFVGAAVDPQSPSWSGLQSRFEKKIAA
GSQFFQSQLISDFEILDKFMNQIAAGCNKPILAGIFLLKSAKNAEFINKYVPGVNIPQHI
IDRLANASEPLEEGIKIAAEQVQLARQLCQGVHVMAVKREDLIPQILDKAGIPPLT
>A0A352P2K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp|TrEMBL
MKLSNILNNKTTLSFEVFPPKRTDSIQTIYNTLNALHELNPDFISVTYGAGGNGNDQTTC
EIASTIKNQYKIESLAHLTCAGLSKEDLLSQLENFKQNGIENILALRGDILDPNQPGGDF
SYASDMISFIKEHGDFDITXGHTESKDLIEDIHNLKRKVDSGADQLITQLFFHNDYLYRF
QERCSIAGIHVPIEAGIMPVINKKQIERMVSLCHVELPSKFIAMMNRYENNPDAMRDAGI
AYAIDQIVDLVVHGVNGIHLYTMNNPYIAKKIHEAVHQLIRE
>A0A142B7B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endozoicomonas montiporae CL-33|TrEMBL
MTTSTLPISFEFFPAKTEEGAKKLEHTASQLADNKPEFFSVTYGAGGSTRDRTLDTVTGL
SRVTGVNTAPHLSCVGDTKEELRTLLKQYQALGINRLVALRGDLPSGMGGFHGELQYANE
LVSFIREETGEHFTIEVAAYPESHPQAPNFEQDLLNFKRKVDAGADSTITQYFFSAEGYF
YFRDRATALGVDIPIVPGIMPITNYTRLARFSDACGAEIPRWIRKQLEAYGDDVKSIKQF
GEEVITKLCERLIAEDVPGLHFYTLNQAAPVQAICRNLGL
>A0A2E6NB44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutales bacterium|TrEMBL
MAAVSLKSRFLSGRALFSIEFFPPKSDSSAEQLLRTAEALKVYSPDFASITYGAGGSTRS
RTLKYARHLSEDYGYAVMPHLTCVGHSRDELRSIIAEFREAGLGQIMALRGDPPXGETDF
KPHPDGLNHANELVGLIHETFPECIVGVAGYPEKHPEAPSPEIDLLNLKRKVDTGGHFVT
TQLFFDNAKYFEFVDRTRRAKIEVPVLPGLMCVNSRKQALRFCDMCGTSMPNELDQQLLA
AGDDAEAVEEVGINWVYRQARELLERGAPGIHLYILNREGPAVELMEKLKAAGFYKX
>Q5F862|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)|TrEMBL
MNYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAASHLTGIDASHDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>Q3JY81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei (strain 1710b)|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A7S4UL91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Guillardia theta|TrEMBL
MESGKRAIETLVAAKAVCSLDVQMHMSCTGITKKMADDLLVEAMDADIRSILVLRGDPAP
GKSDWEPVADGFKNASELVSYIRHKYGDFFSLSVAGHPGKHPASSSKEEDLEHLKQKVGC
GADFIITQMTFKASEYQEFVGSCRRVGIDCPIIPGVLMIPPSLEKLRAVCNHCSVEVPED
LVELLETCGSDKEKVREAGRVYMQRVCSEMLSSGAPGLYMYTLNLEKSAQEIVTNLNLKV
LDAGMSDSAVRPLPFPRPREKETVRPIFWASNAISYLTRTRNWSADFPSQWGQVNNEKSK
AGDHSFVYDPLPSGDEDNILYSHHSIVGRRLGSMAERRNMWGESPSTEEDVFDVFERFVR
GFVPRLPWCDRLEKETLASGILKPLATLNHYGYLTINSQPRVNGAPSEDEQFGWGPRGGH
VYQKAYLEFFCSPGNLDRLLEALGSHPSISLEAFNVNGGRRCVWTDSLGQRNKTDEANVN
DDRHISAVTWGVFDGSEVLQPTIVDSLSFQIWSEEAMDMWKSVWASIYPERSESRSLIKK
IHASYWHVYMVDNDFVKGDIFKVFSEILSLDPYAGSPVITSIKVRD
>A0A2R6AH22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marsarchaeota G1 archaeon BE_D|TrEMBL
MRGSRSEESMKILYEVTPPSKRATRHELDYVVKNASSCGANEVDVTDSPTGESHSSSVAA
CVYIKTKYSLPVMCHIRTRDITLNALRAMVRACAVWEIEHILLVMGEGGENTGLTPTHAL
RVIREEKLLEGSTTKVGFVLQKGKSVEKKIRAKPDFLYTSPLTSVEELEWAVELSRSQNF
ELFPSLIVPSKKNEVILKRIGLQALSAERALTLATHALRLTSNLVVISPADPDEGFSFLK
RLNRNGL
>A0A0L0DMH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thecamonas trahens ATCC 50062|TrEMBL
MKIIEKIRAKEEANEKYFSLEFFPPRTDAGCANLLARLQRMSQLGPLFLDITWGAGGKTA
QRTQVIAQGAQSYVGVETMMHLTCTNQSVESVKEALKEARKAGIQNILALRGDPADGSEE
WTAADTQLRYAADLVRLIREEHGDYFGIAVAGYPSGHPEAESYEADLDNLKAKVDAGADF
VVTQLFFDAAIFLKFRDDCVARGINVPIVPGLLPIQSYASLRHLSKMASTPIPVEITEAV
EAVKNDDRAVRDFGVTKAVEMIQELWAGGVSGVHFYTLNREVATSQIVEALELVCPPPRE
LPWKCINTVPKRAVEDVRPIFWSNRPESYLLRTSEWDDFPNGRWGDSSSPAFGEISDYHL
FHLEPAFKVDEHRAMWGEAPKTIADLAAVFVAFCEGRIRALPWISDALADETTVIADDLI
ALNRAGVFTINSQPAVNGLSSDDPVHGWGGSGGYVYQKAYIEAFVSPTVLAALEALMPKY
PTLQYHALNAASDDLHTNVKTQGAVAVTWGVFPAKEIIQPTVVDVDAFYQWKDEAFKLWL
SRWKRLYADGSPSAALIQSVHDNYYLINIVDNDYVNGDIFAVFRELLTPDALAAAPSS
>A0A7L4M376|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glareola pratincola|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A2U3JVK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacter sp. SbD1|TrEMBL
MSATTPSRLEKIIAAGHLAVTSECGPPRNGDPEVVSRKAELLRNHVDAINVTDNQTAVVR
QCSLASCIRIKLLGLEPVLQMVTRDRNRIAIQSDLLGATSFGVHNILCLTGDHQRFGDHP
TSANVFDMDSTRLIQTVRMMRDEGRLLGGHQMEEGRPQMFIGAAENPFADPFEIRVLRLA
KKVAAGAQFIQTQCIYNMEKFKLWMKQVRDEGLHEKVAVLAGITPIKTVGMAKYMKNKVP
GIDVPEAVIKRIAGVPKENQAEEGIKLCLEQIEELKEEEGIMGFHIMAIEWEEKVPEIVE
RAGLFPRPAVNGSE
>A0A373D6F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotomaculum sp. OF05-3|TrEMBL
MNLREYLKTTNLITDGAFGIYFAAKYQTQDIPELANITATEKVKKIHEEYLNAGAKFIRT
NTFASNKETLQEDFAEVEKNIQAAVEIARDAVNGRDAWIAGDIGPIPVNGAEDAAAAADE
YYQIAKTFAERGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIGEMSLWDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLNVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPILSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTKEDAARLRRIKEETGATILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>A0A7X6GD76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium A_SAG1|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRVVALRGDLP
PGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAATGVDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGA
>A0A8F6TX20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gymnodinialimonas ceratoperidinii|TrEMBL
MTKPSVSFEFFPPKSLEGSFKLWETLGVLAPLSPDFVSVTYGAGGTTRKLTHDAVTTIDA
NFGVPVAAHLTCVDATRAETLEIAEQYAEAGISQIVALRGDPPKGAEGFTPHPDGFASSV
ELIEALAATGKFDIRVGAYPDPHPEAGSMQECVDYLKRKIEAGATSAITQFFFEAETFFR
FRDACVAAGIDAPILPGVLPIENWPRARRFANGCGAVIPQWLDDAYDTALRDGRADLLST
ALCTELCTDLIEGGVDHLHFYTLNRPELTRDVCAALGVTPNVALAEVA
>A0A6L5X9M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porcincola intestinalis|TrEMBL
MKFSDLMKKRQTLSFEVYPPKTEKGMNNLPGMIRRLGELQPDYISCTYGAGGSNVGKNRE
VLREVEKVAVPVTHLTCIGQTKESVRRQLQAYLDQGVTHILALRGDIPYGQSGTGGEFSH
ATDLVAFIRKEFGTAFEIAVAGTPGGHVECSSLEADIMHLRQKQDLGADYIITQLCFDMD
VFRRWHEAIRKAGITIPVDAGIMPVISKKSVINQCFSHNACPVPRDLALVLTQNWFDTDP
EGNEIPGAREAFREEGIAYTVRLLEQYIAEGIDGIHLYTMDRSEDVREVLQRAGLR
>A0A2N0AG37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira harrisiae|TrEMBL
MSKILLEVVPRDTETLLYEVNYVKNTFSQISGINIPDLLRFETRSWFAAASIQNIFPNAI
PHLRAIDFHLDHCDHIIEFLQKNNIPSVLVIKGDPPTDMSQKVYTTTSIKLIKKLKKEMS
SLKVYAAIDQYRSGIKDEFDYIEMKIDAGADGFLTQPFFDLRLIQIFTEKLQGMEVYIGI
SPVITEKSQSYWESRNRAYFPKDFKPNMDWNVKFAKEVIQYCSKNDLNTYLMPIRLSLET
YLSGIFK
>A0A0S7ZID3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium DG_61|TrEMBL
MGKQVLISGSNLERVLAEGHFAVTVEIGPPMDCNAETVIQKARLLKGIADAFNITDNQTG
VVRLSSIASAALIIEEGLEPVMQMTCRDRNRLAIQSDILGAAALGIKNCLCIAGDHQSFG
AAGKLKGHPGAKNVYDIDSIQLVSVLKGMRDNGVQQGGDPIEKRPPLFIGAAWTPLGDPV
EIRPLRLRKKVEAGADFIQTQGVFDIERFSEQMKIIIEMGLHEKTAILAGIIVPKNLGML
RYMNSSVAGVTVPDSLIERMEHARASAGEDKVLARKNQEEEGIKITVELIKQVSGITGVR
GVHIQAIEWEHKVPEILKKAGLVPRPVLEKKGG
>A0A1Y5SE81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimixticola soesokkakensis|TrEMBL
MTAASSARPTPPRISFEFFPPQSIEATFRLARTVDALTPLKPGFVSVTYGAGGTTRTLTH
DAVATLHKIYGLNVAAHLTCVNATKEETLAIADSYYEAGVREIVALRGDPPKGAGQFTAH
KDGFSSSVELVEALAETGKFKLHVGAYPDPHPESGDTDADVAYLKRKIQAGANTAITQFF
FEADTYFRFRDKCAAAGITKPIIPGILPIENWNGVKKFAARCGTPVPDSLDAAFNTAIAA
DRERAYSIENCTKMCEALIAGGVEDLHFYTLNKPHLTSAVLENLGITA
>Q32AD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella dysenteriae serotype 1 (strain Sd197)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVPAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2S3YPN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium americanum|TrEMBL
MSPDINPFDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHEATPTETLVAERLEHLRGGIEENQQQMAEAAAH
HPH
>A0A212QMM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arboricoccus pini|TrEMBL
MSRDATTASADLPPVELSIEIFPPKTAEARERLMANLELFAAAGPRFISVTCGAGGSGED
GTFQLATETASRYAIPVAAHLTCAYASREAIDALVRRYWEQGVRRIVALRGDKPKGALHY
QPRPDGYAYANDLVAGLKAIAPFDVSVGCYPETHPEAPDADSDYRYLLRKIEAGADRLIT
QYCFETDKILRFRDRLVKDGVTVEFVPGIMPIHNFRQIKRFSAACGAGIPDWLEAMFEGV
DEASPVHGMVAATVATEQCRRLAAEGLTRHHVYALNRAELPMALVHLLRASSRMPQAA
>A0A1C6HMY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Anaerotruncus sp|TrEMBL
MPVTNKSQIERMVSLCGASLPDKLAGIIDKWGHNKAALRDAGIAYAVDQIVDLMASGVQG
IHLYTMNSPYVAKKVVGSVQKLLCDLNCTEA
>A0A2H2XX11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix sp. NIES-4071|TrEMBL
MLIVMLDTLTPITPVKVSSFRAAARDGEFLVTAEVCPPKGGNPQHMLQMAATLKGRVHAV
NITDGSRAVLRMSPLVASIILHQNGIEPICQFACRDRNRIGLQADLMGAHALGIQNILAL
TGDPVKAGDHPDCKAVFDLEAVRLLQVIQKLNLGVDYNDKPLTDGALDLFCGAAIDPQCK
SWSGLQSRFEKKVAAGAQFFQSQLITDFERLEKFMDTIAAGCNKPILAGIFLLKSAKNAE
FINRVVPGVNIPTHIIDRLAQAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIAP
ILDMAGVAAVK
>A0A386RHG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADYLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILNRYQNSKEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNHADIAERIWNTTKSVFDAANARTRTTIKHRS
>A0A142Y6S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pirellula sp. SH-Sr6A|TrEMBL
MGLRDYFSSGRGLSFELFPPKSDEGVEQLLVTVGELAEFSPDFFTCTYGAGGSTRGRTLE
ILERVKKQTSIPVASHLTCVGSTVDELRDYLRAAIAIGTDYIVALRGDPPKGETVFQQTE
GGLCYANELVSLIRSEFSQLGIAVAGYPEVHQEAPNAEVDLDNLKRKVDAGADIIVTQLF
YNNVDYFRFVDKCKAKGIEIPIVPGILPVTNLAQIQRIASLCKASLPDSFVSRLQHNADP
SWQFQVGVEFAQAQVDDLLKRGVPGVHFYVLNKSQATSEVLKAHWTVA
>N9BEI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii ANC 3681|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLITGGAPSLHFYTMNTTDPTRQLVLDLGLA
>U2SQP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia sp. oral taxon 215 str. W9775|TrEMBL
MKIKDIFEEKEHVISFEIFPPNKNFSEERLKEVTGELVKHKPDFISVTYGAGGTTKSGTI
EMASHIKNNLGSEVLAHLTCVGSKKTEIDSFLEEAKKHNIKNIMALRGDIPQGEDESIYE
RGDYRYASDLVRGIRGAHKDISIGAAFYPETHYESNDLADLVHLKKKVDEGVDFLISQVC
FDNRMFVDFREKAEKLDIKVPLVAGIMPITNAAQIKRIVQLCKSSIPSGLEKILDKYGSN
PESMKKAGIIYATEQIIELLSYGIRGIHLYTMNKTDTTEEIMNNISFTR
>A0A0S7Y1A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coxiella sp. DG_40|TrEMBL
MKLTERFEKGKFVITCEVGPPKGAEIKESINELEPLRSKIDAFNVTDLQSSVLRLGSLAT
CRLFKEKDLEPIMQLTCRDRNRLALQSDVLSAAALGIENLLCLTGDHPKLGDHPDAMPVF
DLDSVQLLSAVRGLMNGKDLAGNDLEGKPPQFCLGAVVNPGADPLEPQILKMEKKADAGA
EFFQTQAVYEVDKFASFCEKVKHLKVPIMAGIVLLKSPAMAKFMNENVAGIHVPDEIINE
LASVEKERRVQKSLEISARLIKQLRGSCQGIHIMSLGWERHIPCRXGNGPDYDSR
>E5WWS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides eggerthii 1_2_48FAA|TrEMBL
MQGFCQLDKDNEEEMRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYI
NITTHRSEYVYKDLGNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTE
YVLLDLQFLNITDLLVLRGDKAKHESAFTPESNGYLHAIELQDQINQFNKGIFVDGSEMT
VTNTPFSYGVACYPEKHEEAPNIDTDIYWLKKKMENGAEYAVTQLFYDNRKYFDFVERAR
QAGVTIPIIPGIKPFKKLSQLSMIPKTFKVDLPEELTKEVLKCKNDAEAQQVGIEWCVQQ
CKELMKHHIPSIHFYSIGAVNSIKEVARQIY
>A0A1Y2ZYG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenothrix sp. D3|TrEMBL
MQSHPAQLFSFEFYPPKTEEGAASLQVVHNKLAALNPDFFSVTFGAGGSTRDKTFDTVVD
IQAKGIAAAPHLSCVASTKDNIRTILKNYQQHGIAKIVALRGDLPSGTLSAGEFRYANEL
VEFIRLETGDYFDIHVAAYPEVHPQAVNATEDFKNFKRKVDAGANSAITQYFYTAEAYFY
FVDLCEKNGITIPIVPGIMPITQYSQLFRFSEMCGADIPRWMRKRLESFGDDKASVQAFG
LDLVSGLCQRLLDGGAPSLHFYTMNQSAPTVAILENLHIKS
>A0A212L1R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Pleomorphomonas sp|TrEMBL
MRFSHNIGALDLGVSFEFFPPKTEKMEETLWASITRLAPLGPRFVSVTYGAGGSTRERTH
ATVARIVRETDLKPAAHLTCVGASRAEIDDVVRGYRDAGVRHIVALRGDPVGGLGARYQP
HPDGYASTTDLIAGIRAIGDFEISVSAYPEKHPESPDVAADIAMLKRKVEAGATRAISQF
FFDNDKFERYVDRVRAAGIDVPIVPGIVPVVNFEQSAAFAQKAGASVPGWLAQRFEGLEN
DPATRQLVAAAVCAEQVMDLIDRGFRNFHFYTMNRADLVYAICHMMGLRAKTEPAADAIA
VSA
>U2V0L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olsenella profusa F0195|TrEMBL
MDIRDALARKQTLSFEIFPPKGDLSVEQADTIAHALAQSDPDWISVTFSAGGSGNAQSSR
AIAALVERECAPTQALAHLTCMGLAAADADASVDALLAEGVHNVLALRGDRVPGCGTRDF
PHASDLVAHIKHRTPEVCVGGACYPEGHVECESLDADIEALKRKQDAGVDFLVTQLFFMN
EDFYRFRERCVRARIKVPIVCGIMPFTSVRQIQRMAFSCGASIPAKVVKRLVRAGEDPAA
QRAAGVEYACEQLCDLAANGVDGLHVYSMNRPEVGSAAHEALLACGYLGA
>L0K8A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteroides halobius (strain ATCC 35273 / DSM 5150 / MD-1)|TrEMBL
MLLQDKLKTKDFIITAELTPPKGTDCQTMFQVAQDLKEKVDAVNVTDSPMAKMKMSSIMA
GHFIQEETGLEVIPHVTCRDKNIIALQGELLGASKLGINNILAITGDDPTRGDHPQASPV
FDTNSIGVIKTVQKLNQGFDTNDNQLTGTTDLTVATAGNLGADDLDEEIARLETKVTAGA
DFIQTQPAYDLDLLKKFLDKTNHLDVPILIGVLPLTSYKMAQYLDQNVPGVEIPTSILAR
MKGKKAAEGVKISSQFLKQVSDLINGIHIMSANRSDILLDVLNEVT
>X6DAG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNHC252B00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDQVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVR
TAH
>A0A2N7JD07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio kanaloae|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVATL
>A0A7C5CF06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacterales bacterium|TrEMBL
MFKKFCKTLHSNEPFITIEITPPHGASIKGIIDNIKELGLDKKVSGFSVTDNPLAKLKMC
ATLSAIQVQNSFDKPAILTMSMRDKNKLSLQSTLLGANDFDIRTILALTGDPAKLSDQPE
VKGVLERDSTLLLSIIYHLNNGFDYSNKELKPKPKPIYPFAVSNAYAKDMNRIKKRIVKK
LNYGARGIITQPVYDIENAKELIEIFNEAKEESIRETAKEAELILGQFPVVRAKTTNFIS
DKVPGITVPKDIIDEMNLASMDGIEKEQEVGFGLSKRIFDDIMDMHPKVHLMTHNNFNLC
NELIG
>A0A6N2VDX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia hansenii|TrEMBL
MKLSDAMREKMLLSFELFPPKTDKGMENLPGTIEHLCKYKPEYISCTYGAGGTNVGKNMD
VCKMIKDAGTIPVTHFTCIGNTAEGIKEQLQNYLDNGVDHMLALRGDLPFGWTGTGGDFA
YATDLVAYVRKEFGDKIEIAVAGSPEGHISCRSLEADIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRCAGITMPVDVGIMPILDQAATINMALSRNACVMPRELCEIISKNWIFPN
PFVQDPFDADVEGKKARFKEAGIEYTIRQIDEYRACGIDGIHLYALNKWKDVSEIIDRSG
LRTLV
>A0A6P8WZE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila albomicans|TrEMBL
MCFNLSRILSHTTFLRSMRTIKRNQYHSHCKYHWMFAKRLCSSEANASAIKPYFEFTDDQ
KEHCLNDPNIAEIVKEKSKRKEFFYGIEIPLKMDLNTCLDFKMFLPQMPEFMSIVWTKQF
SDAIRSASMAKLPNIQTVSHLTPFIPAMAHISLHRLTQQHLNDFLDLNLNNVLVIRGDHV
EEGQEYNYAYEAVKYLRAARGSWQLLSLVIRKDTRICKLDRETRL
>A0A8F9TXK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleiharenicola sp. KSB-15|TrEMBL
MNRLAERLGASSDFLIGVELVSTRGGLDQPHAAKTLSLARDLAGAASIDWVSITDNAGGN
PMLAASALGAPLRDAGREVVIHLSCKDFNRNALESEAWRLASEGFQNILVLTGDYPGHGV
GGGGKPAFDIDAIGLLTLLGQMNAGLDVTREGAKKAVRLEPTKFFPGAVVTNFKLLENEV
IPQLLKMERKLAAGARFLINQIGYDSRKVHELIAWMRRRGHGHVPLIGNVYVLNPGVARV
FRAKKIPGVVISEELGDICEAQRAAADKGKAFFLELAAKQIAIYRGLGYRGAYLGGVHSV
AEIERVLEIERGFAPDDWKQFAREIQYSRPGEFFVFARDENTGLANPEKLEATYAASLGA
HPRTQNVTFTYRFSKFAHELMFTPGKGLWKAGDALCASAKDPLQGPAWMRAIEHTSKRLM
FDCRDCGDCSLSEMAFLCPESSCAKNQRNGPCGGTRDGKCEVYDYECIWSRAYERLKFEG
REDQLLAHTPAVQDQSLRYTSSWANTWARRDHLAKHPPASLPPIKS
>A3RPV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia solanacearum (strain UW551)|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRDILDTYRANGIRRLVALRGDLPSGMGEIGEFRFANELVEF
IRKEMNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAGATRAIWQRLGL
>A0A560PQU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SJZ078|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLANHNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRTLLARYKAAGIQRIVALRGDLPSGMGMASGELRHASDL
VNFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVNKANSGANSAITQYFFNADSYFY
FVERVRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQRFG
EDVVTQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLNLPR
>B7WYN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas testosteroni (strain DSM 14576 / KF-1)|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>V5WL52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinispira pacifica|TrEMBL
MLVKDIFNGCNDEGKIPFSFEFFPPKTPRGWEKLFKTMRELLPLNPAYVSVTYGAGGSTR
DNTHDLVSRIHGEGLPVVAHLTCEQSSESEIAAILERYDREGIHNILALKGDVPLPVGSV
DKGRSTGADDSATADTPFTYAADLVAYIKRKYPHFGVGVAGFPEGHPATANRLKEMDYLK
AKVEAGADYIVTQMFFDNRDFYDYRERCRMAGIDIPIIAGLMPVTSVKGMEKMAELSGGS
RFPAALLQRLKRTVNNNGGQWGIYGAAENNTPEVRDAVSRVGEHWTSEQISDLLNHQVAG
IHLYTLNNSGASIRIMKSLGLESYSVRG
>D3RMM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D)|TrEMBL
MTTSTTPTRVYSVELFPPKTAEGMDKLKQEIPRINALGPAYFSVTYGAGGSTREGTFETV
AWLRAQGIDTAPHLACIGSTRDQVREILAHYHEQGINRLVALRGDLPSGMGAGNSGDFRY
ANELVSFVRAEFGDAFVIEVAAYPEYHPQSGSPARDLENFKRKVEAGAEAAITQYFYNAE
AYFGFVESCERAGITIPIVPGIMPITNYTQLARFSDACGAEIPRWIRRRLEGYGDDVESI
RAFGHEVVLGLCRRLIEGGAPGLHFYTMNQSGPVTRLWSELGLSD
>A0A562T9C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium hamelinense|TrEMBL
MTIPFASRRSRQKNTSPITASFEFFPPKTDKMAANLWDTVQRLQPLAPSFVSVTYGAGGS
TRERTHTTVERLLKETSLAPAAHLTCVGSPKSEIDSIVQDYWDLGVRHLVALRGDPLEGI
GARYKPHPEGYAYASDLVAGIKKIANFDISVSGYPEKHPESGSWQSEIDNLKRKVDAGAD
RIMTQYFFDNDVFDDYLDRIAAAGINIPVVPGILPIHNFEQTMVFSAKCGTTIPDWVARR
FAGLNNDPETRKLVGVSIACEQVMDLVDRGLTDFHFYTMNRADLTYAICHMLGMGQHAPE
KAAA
>A0A4R1QSS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fournierella massiliensis|TrEMBL
MRLSQVFRQKECVFSIEVFPPKKNGATPESLYPTLEKLAGLSPDYISVTYGAGGGKAGLS
TVQIARHLKQELGVEPLAHLTGINSTREQVAETVQALQKAGIENVLTLRGDICPDAPRSK
DFFHASDLASFVKSKGDFYLAGACYPEGHVESENLRQDVENLKYKLDAGVEHLVTQLFFD
NARYYRFMNLVRKAGIQAPVQAGVMPIVSARQVQRTVALSSASLPPRFTKMISRYDGDEA
ALFDAGIDYAIEQLRDLIEGGADGVHLYAMNNPEVARRVYEGIRDLLPEAKA
>A0A139RDM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus infantis|TrEMBL
MSRQTPSLSFEVFPPNPEVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFITEQAPHFDIVGACYPEGHPDSPNQISDIQNLKRKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQP
>D2RMA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4)|TrEMBL
MKIIDLLKSPKVCVSCELFPPKKGSELEHAQEIVRTIAIQGVDYMSVTYGAGGTAVGKSV
ALVSEIERCGVPALAHLTCVGADEGKIEGVLDQLKDAHVENVLALRGDLPQGQDHPLGDY
AHASDLVKKIKSYGDFCVGGATYPEGHPEAAGLDEDLEHTKMKVEAGCDFLVTQMFFDNS
MFYNFMYRLLAKGIQVPVVAGIMPVTNLKQIEKIFTLSGTPVPAPLRAMAERFADHPAAL
KQAGMAYAIGQIVDLIANGFTNIHIYTMNKPEIIGGIRSNLSEIIRC
>A0A368BDB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR86 cluster bacterium|TrEMBL
MEVNKNIQNFLAGYSIEVTPNAAAKIDNFSDVLPKNTLVYIAHIEGTSIDEMVNTAKKLK
DHGFESMPHFPARIIKNKPILHDWISRYKNEAGVNQALLLAGGANKPYGDFDSSIDLLES
DLFNKADFKTLHVAGHPEGSKDIDPDGSNSNTNQALLWKNDFNKKTDANMAIVTQFCFEA
STVISWANQISDLGVNIPVHIGIAGPAKLQTLLRYSIECGVGASINVIKKRAKDITKLLL
PYEPNNIISDLANYKKENPSFIIEKVHFFPLGGIKTAAKWAKSA
>A0A2C2VMP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS031507|TrEMBL
MSFLDKLKNQILIADGAMGTLLYSFGKDSCLEELNLSQPGHIQTIHKAYIDAGADVIQTN
TYAANYLKLQRYGLEDSVKEINSAAVSIAKKAAAQNDTYVLGTIGGNRGIKPDSISIEEL
KRSFREQLYCLLLEGVDGLLLETFYDFEELETVLTIARKETKLPIIAQVSHQEPGLMQDR
TPVNDALKRLEGLGADVVGLNCRLGPHHMLLALEQIELPAHAFLSAYPNASLPAYTDGKF
HYEGDADYFRNSAKAFRNQGVRLLGGCCGTTPDHIRAYASELKNSVPVTEKIVKLKPKKI
IVESHSSKREYTPLQDIVKERPSVIVELDPPRKLDTTKFFQGAKALKEAGIDSITLADNS
LATVRISNESLGYLVKQDLGMRPLIHIACRDRNIIGLQSHLMGLHTLGMNDVLAITGDPA
RVGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTDFSIAAAFNPNVRSLEKAV
KRLEKKVHYGADYFISQPVFSEEKLLEVYEHTKHLDAPIYIGLMPLISSKNAEFLHNEVP
GIKIADSIRQRMAQLNDQPLQAAREGIAITKSLIDAALDLFNGIYLITPFLRYELTAELA
LYTRQRASELRRSTYAENTIY
>A0A5J4QWD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
MKIIDLIADSKHTAFSFEILPPLKGTGIGKLYDMIDTLREFNPKYINITTHRSEYVYTDI
GNGLYQQNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLIDLQFLGITDL
LVLRGDKAKHEPVFTPEENGC
>A0A7X5SBV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas perforans|TrEMBL
ETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDAVQRMGVEIPIIPGIMP
ISNFSQLRRFSEQCGAEIPRWISKKMQSYGDDADAVRAFGAEV
>A0A7K3GYH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5789|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPTADWIAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSVGWDADVRHFVD
KCRAGADYAITQMFFQAESYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPKLSNAVF
PPELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A7U9ERK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. A8|TrEMBL
MGLLDKLKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEEAAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTRRSVIVELDPPKQLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIVKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACGGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>F2JGX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulosilyticum lentocellum (strain ATCC 49066 / DSM 5427 / NCIMB 11756 / RHM5)|TrEMBL
MIEKAIKHAKKPSFSFEIFPPKGTADLSGVYATIDGLASLAPDLISVTYGAGGSSRENTV
DIASAIQNKYDIPALAHLTCVGSTKAEMDDILTHLKDKGVKNILAMRGDLGENAVLGDFK
HASELIAYIKENYDFKVFGACYPEKHIEAYSMGEDLKHLKHKVECGTDELISQLFFDNNA
FYSFIDKVRGIGIEVPVVAGIMPVTSAKQIDRMVSMCGATLPEEVQHFVKAYGHNSMAIK
EAGIAYATSQIIDLLANGVDGIHLYTMNQPEVAKRIVENIRGILYALKVKRA
>A0A1Q6MN41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. 36_13|TrEMBL
MSANGKEKIIEYLKSNILVTDGAMGTYFASLYDTKEPPEYCNIKDSKKIYDIHRQYIENG
AKIIRTNTYACNTFTLNYEIEDVKESIKCACKIAREAAKGHEDIFIAGDIGPITYNHNDM
QKQVSDEYVVIAKTMIESGVDAIVFETFPDMDDIKEALKYIAEKGNIFVIVQFAVNQFGY
SNSGLSAKKLISDALDCEYTDAAGLNCGVGPGHMYGIFEKLGINTAKYLTALPNAGYPQS
VSNRMVFAADNSEYFSIKASDMAERGINIVGGCCGTTPEYIAKLENAVKNMHPVKHFSEE
HEKKIMFKPIDKSFYKDKSGKKLIAVELAPPVDSDDEKLMDAAHILKKSGVDVLTFPDSP
SGRTRADSILMAEKVHKETGMTVMPHICCRDKNAIAMRSQLLGAHLNDINNFLVITGDPI
PSMVRQSVKAVFNFDSVGLMNIIKDMNESQFENSPIVYGGAINQTRRNLDVEISRVRKKM
DAGATFFLTQPVFDDKGIARLRQIKQETGARILCGIMPFVSLKNAMFMKNEMTGIEVSDE
IIARYKECVTKEDGESVGVEIAKEVIEKTSDFVNGYYFSFPFNRVYLLERII
>A0A7V5C8U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium|TrEMBL
ENWAGVRKFADNCGTKVPAWVNDAFEKAARDGREELLSVALAAELCSDLIDGGVEDLHFY
TLNKPYLTRDIAHALGVQPQAVLQKVA
>A0A088U4Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cenocepacia|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATRTICERLDT
>A0A1V0HYC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum sp. (strain MB263)|TrEMBL
MTAPRVSFEFFPPQTLEASFRLWEAAQALAPLKPTFVSVTYGAGGTTRKLTHEAVETIHN
HYGLNVAAHLTCVDATRAETLEIAEAYAAAGVTEIVALRGDPPKDQGAFRPHPEGFANSC
QLIEALAATGKFRLRVGAYPDPHPEAGAPDADVLWLKRKFEAGADTAITQFFFEAETFFR
FRDACEKQGIDGAKIIPGILPIEKWAGVRRFAQRCGAHVPPHVDAAFETAIRDGREGLLG
KAMATELCTGLMEGGVRDFHFYTLNKPHLTRDICHALGVVPDAHLEKVA
>A0A2S0LDS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 878|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYQNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYAAELVTQIINLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVEACKNNADVKQVGIEWAIQQSKELKAAGAPVLHY
YSMGKSDNIVKVISEVF
>A0A2D9YLQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritimibacter sp|TrEMBL
MSAPRLSFEFFPPQSLEASFRLWDTVRTLAPLGPEFVSVTYGAGGTTRDLTHDAVKTIHA
NYGLNVAAHLTCVEATKAETLEICDRYAEAGVTEIVALRGDPPKGAGAFTPHPDGFADSC
ELISALADTGKFKIRVGAYPDPHPEAASDTADIDWLKRKIDAGATSAITQFFFEADTFFR
FRDRCAAAGIDAQIIPGILPVENWKGIKRFADRCGANVPQWVIEAFEKAQRDDRHDLLAV
SLCSELCTDLIEGGVEDLHFYTLNKPHLTREVAHALGVVQPASLRDVA
>A0A1T1BUA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. LM4|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKHEQSFVPKDGGNHYAVDLVRQINDLNCGKYLHEVMDIDNRADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFNFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>C7LW31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomicrobium baculatum (strain DSM 4028 / VKM B-1378 / X)|TrEMBL
MRISQLLQRQEPFLSLEFFPPKDRAQWPGFFDVVRQLRALAPLFCSVTYGAGGSTQHNTL
EIVTRMKQEYGLEPLAHLTCVGADRARLGSFLSGLGEAGVDNVLALRGDPPRGETSFTPD
SEEFQHGSDLVSFIRQEFSDLCIGVAGYPEKHPEAPSMADDLERLRHKVASGADFVITQL
FFDNDRYFDFVVRARAAGIGVPIIPGILPVQNLGALQRMLTFCGASVPEGYMRDLEHVHK
VYGESGVRGLGLGYAKSQIRNLLDRGAPGVHLYTLNKADTCLDIWKDFSSRDGLK
>A0A840IE68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Conexibacter arvalis|TrEMBL
MARIEQTFSSAVEPVFSFEFFPPRSPRGVENLERALRDLQPMAPDYVSVTYGAGGSTREG
TIECVLRIKHELGLEAMAHLTCVNATVDDLRAVLDRMRDGGVENVLALRGDPPRGQTRWT
KTDGGLEFSRELVELMVGEYDFSIGSAAFPETHIHATSPEDDLRHLKAKVDAGARFLITQ
MFFDNRFYFDFVERARAIGIDVPIVPGVMPILSIDGVRRMSELSAAHMPAGLLRELEARR
GDDEAVAELGVAYATLQCSELLARGAPGIHFITLNRSPATRAILSALRLTRPWERHAGG
>A0A8C8WUS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panthera leo|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEANSGRFSVPPSISRNPAMVNEPRGDGGPTSRSEGSS
SGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCCQSREQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDVCVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMWGEELTGEESVFEVFACYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPGQQGTETL
>A0A850SB80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvularculaceae bacterium|TrEMBL
MSDLHVSFEFFPPKTEAMQQKLWSAVQKLAPLSPDFVSVTYGAGGSTRERTHETVTRILA
ETSLGVAAHLTCVAARREEVDDVLRRYWASGVKHIVALRGDPPGGAGEPYRAHPGGYANA
AELAAGARAVAPFEISVGCYPEKHPDSPSLSADIDMLKRKIDAGASRAITQFFYDNTVYF
RFLDRVRAAGIQIPIVPGVMPVTSFAGLRRMADLCGATIPGRLVKLFQNLDEDPATRQLI
AATVAAEQCHDLAEQGVKHFHFYTLNRDDLAYALCLMLGVRPKPASPKSSEAAA
>A0A679IC83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fluviibacter phosphoraccumulans|TrEMBL
MTQPAVELSVEYFPPQTPEGLDKLRVVREKMAVLKPTFCSVTYGAGGSTRERTFDVIREM
VSEGIDAAPHLSCIGSTRDSIREILDEYLDLGINRIVALRGDLPSGMAEAGEFRYANELV
EFIRETTGDHFHIEVAAYPEWHPQARTPADDLRAFVNKMAAGADSAITQYFFNADAYFNF
VEAARNAGVTQPIVPGIMPISGFTKLARFSDACGAEIPRWMRRTLESYGDDTDSIKAFGL
DVVTDLCEQLIEGGAPGLHFYTMNQSALTLEICRRLGL
>A0A6V8NUH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hakubanella thermoalkaliphilus|TrEMBL
MKSGSNLEKVLSSGHFAVTAELGPPKSCDPEVVEKKAEILKGFADAVNITDNQTAIVRTS
SIATGVIVARKGLEPVVQMTCRDRNRIAIQSDLLGAAALGIKNLLCLTGDHQSCGNHPQA
RGVFDLDAIQLIDMVRRMRDEKKFQCGEEMSVEPRFFIGAAANPFADPFEFQVIRLAKKV
TAGAEFIQTQLIYNVEKFARWMKMVREMGLHEKTYILAGVGPIKSAGAARYMKNKVAGMD
VPGEIV
>A0A3D8X293|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia megaterium|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINIAGVKLAKQAVKDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLNEGVDGLLFETYYDFEELKTVLTLARKETDKPIITHVSLHDIGVLQDGR
PLADALKELEDLGADVVGLNCRLGPYHMIQSLEEVPLPDCAFLSAYPNASLPAYVEGKLE
YETNEDYFVESARLFREQGVRLIGGCCGTTPAHVRAMSSALKDQPPITSKVVKMRPAVKV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRIRGEVEGLAIAKNLIDTAYELFDGIYLITPFIRYEMTEILTRYI
HDKQLVTSERKI
>A0A1E5B6W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio splendidus ZS-139|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVKLLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A3C2BC12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKIKDMFKQKTVFSFEVFPPKKDSSIDVVYKTLDELKGLSPDFISVTFSAGGSGNGSLSC
DIASKIKEGNKVEPMIHLPCINYSEDEISEILQEIDKRGIENILALRGDINPNIEPKRNF
EHASDLITFIKSKGNYDIAGACYPECHIEADSFVDDIQNLKKKVDAGADHLITQLFFDNE
AFYKFREKVAIAGIDVPIEAGIMPVVNKNQIERMVSMCGASLPAKFSKMMQRYENNPEAL
RDAGIAYAINQIVDLLADGVDGIHLYTMNNSYVATKISEAVCGLVGSRTK
>A0A3N3DYB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio ponticus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFISVTY
GANSGERDRTHSIIKDIKSATGLVAAPHLTCIDATREELIQIADDYWSNGIQSIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPR
>A0A2N3EW70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HGW-Alphaproteobacteria-1|TrEMBL
MKTPRVSFEFFPPKSLEASFRLWDTIHTLAPLAPRFVSVTYGAGGTTRELTREAVGTLHK
ATGLNVAAHLTCVNASRSETLEIAEQFHAAGVREIVALRGDAPKGSDGFTPHPEGFADSC
ELIAALAETGKFTIRVGAYPEKHPEAADQKADIDWLKRKIDAGASEAITQFFFEAETFFR
FRDACAAAGINAPIIPGILPIENWVGARKFALSCGTTVPAWLDDAFDKALRDNRHDLLAT
ALCTELCSDLIEGGVEDLHFYTLNRPDLTRDVCHALGVTPKVTLRDVA
>A0A090PQ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio ponticus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFISVTY
GANSGERDRTHSIIKDIKSATGLVAAPHLTCIDASREELIQIADDYWSNGIQSIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDEDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPR
>A0A510ZDT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas halophila|TrEMBL
MSAQEHPLGISFEFFPPNTEAGRDKLMQTRDALATRGPRFFSVTYGAGGSTQHRTTDTVR
MVRESGFTTAPHLSCIGSEKAALRDLLAQYREEGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFNIAVAAYPETHPQAPNADRDVENFARKMKAGANLAITQYFFNADAYF
RFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSESIAAF
GEDVISRLSQRLLDGGAPGLHFYTLNQAEPSLRVVDNICG
>A0A1E7JD28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium C00003063|TrEMBL
MKLKDALKKNQFIVTSEVQSPVEDDPEKLIQNLQLIRGRVDGVSVSEIEIDGVVGDTIKT
CDLLKKSNFDPIYQTTTRQKNRLQLQKDLIGAHEAGIENLLVFTEDYRLTGDSLQEMMFF
HVDAGKLSSVLDHLKEGHTVEGDALPEKTEFLLGSGVESSWGKNIPDLEMREMEEMTKIG
TGYFLTTPVFNLDSFEKFIKNVNTFGVPVIAEVLIIRTAGMGQFLNRHMKPGLVPDWVIK
KLSQAPEKQKASIEIFADIVSGLKDICQGVHIISIGGEQRLRQYLDAAKLK
>A0A2N0DAM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sullae|TrEMBL
MALNTGDRRNIGISFEFFPPKSEEMEGQLWKAVAELQDWSPDFVSVTYGAGGTTKAPTLT
AVTRFLNETPLSTASHLTCVGATKEETHQVIDHFRNVGVKHFVALRGDAPGGAGVPYQPH
PGGYANAAELVAGLRGIGDFEISVSAYPEKHPESRDVASDIDMLKRKADNGADRALTQFF
FDNDNFERYLEKVRAAGVKIPIVPGIMPIQNLTQLKRFASACGTVIPAFLDERFAGLDDK
VDERAKVAADVAVEQIEDLVRRGLDEFHLYTMNRSPLVSAVLTNLGLRREGAKRVAGAAA
>D9UHN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. (strain SPB78)|TrEMBL
MPVWPPAPHPPGPPSTRPWRRCSRAGKRSYSLRVSGRPKTPKGRSANPVESRWRLVEGRL
ALVFFLGEVTVRGGQLPVSATRGAPTQAIAENTTLVPVAHLTAVEHSVAELRHMIGQYAD
GGVRNILAVRGDPPGDPLGDWVAREDGLTYAAELVRLIKESGNFCVGVAAFPDMHPRSEN
WDSDVRYFVDKCRAGADYAITQMFFDPASYLRLRDRLSAAGCETPVIPEVMPVTSVRQLE
RLSRLSTAVFPETVKERMLAAKDDPAAVRSLGIEFATEFCARLLAEDVPGLHFITLNNST
ATLEIHENLGLPHHRP
>A0A7Y4XWM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium|TrEMBL
MQIQPSQLFSFEFYPPKTEEGAASLQVVHSKLAALNPDFFSVTFGAGGSTRDKTFDTVVD
IQSKGIAAAPHLSCVASTKANIRSILKDYQEHNIGKIVALRGDLPSGMMSAGEFRYANEL
VEFIRHETDDCFQIHVAAYPEVHPQSTSAVEDFKNFKRKVDAGANAAITQYFYNAEAYFY
FVDNCEKNGITIPIVPGIMPITQYSQLFRFSEMCGADIPRWMRKRLEGFGDDRAAIQAFG
LDLVSNLCQRLLDAGAPGLHFYTMNQSAPTLAILENLRK
>A0A6L7IGI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium W22|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHGSAMELVHQINDLGRGKYLHNQDEICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVKKAREMGITVPIIPGI
KPIATKKHLKVLPQIFKIDLPEELINEVENAKNNEAVKQIGIEWAIAQCRELLKFEVPVL
HFYSMGKSDNIKKVAGALF
>A0A5N9AWB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MPDNTSFNESLEKGTILGDGAMGTLLYQMAMKHDTKPVEELCLSRPDSVRLAHIEYIRSG
ATMIQTNTFAANRNKLASYGMTDSTSLINKAGIEIAKEARRLTGQQVWIAGSVGPIGRHL
EPIGTVSLVSARKFFQEQVDALAEGGADLIILETFSDLREVELAATAATSACLPFIAQMA
FGHDGLTSLGHSPGEAAAAMESMGAAVVGCNCSVGAAPMVSTVSQMLSRVSIPISAQPNA
GFPTMHQGRTVFGSSPEYMASQATRLVDAGASLVGGCCGTSPTHIAAIRDSIPTRARPKK
DQLPSRRITISTREPFLSSDNEIPEPSTFSTKLKEHKKVITMEVDPPRGFRASSELSQLE
QIRNAGVLDAINIADNPRAQRRMSPLAMATLVQNRLGMETIMHLALRHRNYASLHSDLIG
AHALGIQNIFTVMGDKPRFDNYVNPYTPSNLTTTGALNLMKSFNGGLDLSGEPLESPTAF
LKGASFNPTAKDPDREFRLLESKLEAGADFLLTQPVYDSAAVQKTAQKFGGFPIPVLIGI
LPLRSKRNAEFLQNEVPGISIPPEIMEAISSSSDPRRTGMDISRRIVTELSDTVSGVYYM
APFRRYESIIEFTESLDFA
>A0A853BES0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis endophytica|TrEMBL
MSERVLVFDGAMGTVLHAAGNSLDRALPELNLSNPELVSTIHESYVAAGADVLLTNTFGA
NRLRLAEHGCSVSVRDINLAAVRLARQARRGTHRTIFVAGAVSPAVSPGQRAAVRVDERL
DVVREQVTALVDGGVDLLVLETFGFLDELVEAVEVAAELTDLPIVAQASFTADCLTPGGE
TPREVAKAVSALPVTAVGANCTLGPQHMLTVLDELKDAVDLPVGVHPNAGMPRRTGRRFT
YPVARSHFGRYARRYAEHGAAMIGGCCGTTPGHIREVVARLADLRPRQSRPVTAVPKPRP
APPQSPLARRLARPGFVLAAQITPRGGPADAELIRATGADLVLVRGHFGDALHLERETGV
DTITTVTAWDRSLAALQADLLGAHAFGLRTVVCETGTPAPLGDYPGADGVWEVDSTGLIG
LLAGLNAGRDHTGLTLATRTSFHIGARVNPGAEDADAELARTRAKLAAGAQFLITRPVYE
LGGLTRMLSELSGVDVPVLVAIAPLSGYAEAEYLAYEVPDVTIPPQTLSALESAGEQQAE
VGLGLAAELLERARDLVRGAVVVADDLTGEIESLLGQQRSPA
>A0A7L6JTN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. RHBSTW-00524|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIAQDYWHNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A368UG00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gallolyticus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADIIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAREAAGDDAFVLGTVGALRGLKHCDLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDGN
GSGQYGFSQNADYFGKSAELFVAEGVRLIGGCCGTTPDHIRAVKRAVKGLKPVERKLVTP
MVEEAELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIATFTEGVKALDKAGISAITLA
DNSLAKTRICNVSMAALLKNEVSTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKETDFKVAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDELADLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKEDKETCQKLALEESKQLIDCALEHFKGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>C0EVI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum hallii DSM 3353|TrEMBL
MRMNIREYLENHKLLTDGAMGTYFDSIEKENYICSEEANITNPALVREIHRSYVKNGAQL
LRSNTFLANEGTFLSLTQAKAEAFENITLKQLIIAGYQLAKETAQEVYQEEYPIFAAADI
GPILEERDSEEADILQQYYEICDSFLEAGADIFVLETFPDTQYVLKMAEYIRKSCPEAFI
IGQFSLTPTGYSRTGFHYKTILQEATQSGLLDGAGLNCGVGAAHMKKFLKSYIEEFGVPE
DMVLTSLPNCGYPQIVRGHAVYSDSVPYFGEKLGEISELGVQVLGGCCGTTPEYIGEIYK
TVFQAKKTEGAVKIPTKIVWGDVTKRVQKRKEAAVHITQAGEQKEAIKEKQVTNTFRQKL
EMGELVCAVELDPPFDTDDTKLLNGAKALLSTKADIITIADSPLARSRADASLMAAKIKM
TTGMDVMPHLSCRDKNRIAIRSGLLGSYASGIRNYLFVTGDPVAREDREFTKSVFDFNSI
RLMKFAQSMNQEVFKDDTIFYGGALNQNGASPENIAGRMLKKMEAGCRYFLTQPVYDKEG
IERLTFLKERTGAKILIGIMPLVSRRNALFIKNEMPGIHVPDEVVAKYKEGASREEFEEA
AIEISKQIIEMGKGIGAGFYFMTPFNRVSLVKSILEYV
>A0A6H9JDJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MISQLQNRLESGIFTVTAELTLPDSSIKDELVETALKLSPYCDALNVTDATSAIPHFSSL
AAASILLDNDIEPVMQISARDRNRIAIQGDVLGAHSLGIRNIFCITGDAVIFGDHPDAKP
VFDLDSISMLAAIEKMTKDGCFMSGRKITPKPALFLGAAANPFAPPQSYRPHRTVKKWRA
GASFFQTQFCFDLQIMKSFTEKLIELCNGKPPPILAGLGPLKSSRMARWLRDKIPGVSIP
DHIIERMEKYPQKDQAQVGLEISKETTENLKLIRGISGIHIMAYKWEQAVKDIVEDTGLS
KNKRLP
>A0A6P1YHF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylobacter pratisalsi|TrEMBL
MSSDIERRSRRAGGRPISVSFEFFPPKSPEMESTLWNSITRLAPLAPKFVSVTYGAGGST
RERTHATVERIVSETRLAPAAHLTCVSASKDEVDEVVRGYWEAGVRHVVALRGDPPGGVG
QAYEPHPEGYTTSADLVAGVRRIANFEVSVSAYPEKHPESPSFETDLDILAAKVDAGATR
AITQCFFDNDLYFSYLDKVRARGIDVPVVPGILPVTNFKQAVNFATKTGTYMPSWLAGRF
EGLDNDPETRKLIAAAVAAEQVFDLLDRGVTEFHFYTLNRADLVYAICHLLGLRPPRDAG
AGQGSGQAAA
>A0A8C5E2Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gouania willdenowi|TrEMBL
MGKQTPHGDGNWQSSKSDSSGASGGDSSKESSRCSTPVLDADRSDRLRDKMRKRIESGDH
WFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVN
YCGLESILHLTCCNQSKEKITAYLNKAKHLGLKNIMALRGDPVGSEWEDEEGGFNYAIDL
VKHIRSEFDDYFDICVAGYPTGHPEAETYEADILHLKEKVDAGADFVISQLFFRADTFLK
FVNDCRAIGIKCPIVPGVFPVQGYQSLRQLAKLSKLEVPEEITRVIEPIKDNDAAIRNFG
IHQAVEMCRLLLDSGIVPGLHFYTLNREVATMEVLRQLGLWNEDPRRPLPWAMSAHPKRK
VEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALL
QMWGEELMNEQSVYEIFTCYITAQSNPCGHKVLCLPWNDEPLAPETNLLKDELEKVNRRG
VLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKILKKYEPRVNY
HIVNVNGRNWTNANDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKL
YEDESPSRMIVKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLSEAQELLSDGAISE
>A0A1T2LAE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solemya pervernicosa gill symbiont|TrEMBL
MKSQQNHPKQFSFEFFPPKTDKGAENLRQVRDELATLNPKYASVTFGAGGSTHAGTVETV
REMMAAGLDTAPHLSCIGSSEEDIRALLNGYIEMGVKRIVALRGDLPSGMGMGGAGAFNH
ANELVEFIRSETGDHFHIEVAAYPEFHPQATSASADLDNFAHKVKAGANAAITQYFYNLD
AYLHFVDECEKREITIPIVPGIMPITNIKQLARFSEMCGADIPRWLRLRLESYGDDMESL
RAYGLEITAELCRRLLEAGAPGLHFYSMNRVEPVKTIWQQLDLSND
>A0A1B4FA90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia mayonis|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFVRKVKAGANAAITQYFYNADAYFRFVE
DAAKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKLVCERLGL
>A0A417LTV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. TM06-18|TrEMBL
MKIKDILAEGRPTLSFEVFPPKTADAYESVEKAASKIAQLKPDFMSVTYGAGGGTSDYTV
KIASTIKEEYGVTPLAHLTCVSSTREKVHHVLEELKAHKIENVLALRGDIPQDGKTPEVY
HYASELIHEIKEAGDFCIGAACYPEGHPESSNKSVDMDYLKEKVDAGCDFVTTQMFFDNS
LLYSYLYRIREKGITIPVIAGIMPVTSGSQLKRIAQMSGSYMPARFLSLVDKYGDNPAAM
KQAGIAYATDQIIDLLANGIKGIHVYTMNKPDVAAQIQSNISELLK
>A0A5N9GMA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MTSQLQNRLESGIFTVTAELTLPDSSIKDELVETALKLSPYCDALNVTDATSAIPHFSSL
AAASILLDNDIEPVMQISARDRNRIAIQGDVLGAHSLGIRNIFCITGDAVIFGDHPDAKP
VFDLDSISMLAAIEKMTKDGCFMSGRKITPKPALFLGAAANPFAPPQSYRPHRTVKKWRA
GASFFQTQFCFDLQIMKSFTEKLIELCNGKPPPILAGLGPLKSSRMARWLRDKIPGVSIP
DHIIERMEKYPQKDQAQVGLEISKETTENLKLIRGISGIHIMAYKWEQAVKDIVEDTGLS
KNKRLP
>A0A1F9QZN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium GWA2_66_18|TrEMBL
MDIPELLAATERPLFSFEFFLPKAPEDLDAFVAFVRELKDLSPDYVTLTYGAGGSARERT
IEIAGRLQRETGLTTVSHLTCIAHTRAEISAILLRLEALGIRHIVALRGDAPKDAALRPV
EERDFAHAVDLVRHLRERGGLRTAVAAYPEKHPESPSPEEDLRRFAEKVAAGGDWAVTQL
FFDARDYFAFVRRAREAGVKVPIVPGIMPVTGYPQLKRFVGLCGARIPPELDERLSAIQH
DSQAVVAFGVDWAVRQCRALLDGGAPGIHFYTLNRSHSTAEILSRLRRP
>A0A3D2GDC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium sp|TrEMBL
MSITNNTNGSTKDERNTFSQKLVCEILDKRFILETLPPRATTPDKYLDFCEKAVESGAQV
IAVTDLPMGSSRTSPIAPAHMLVERGISVLMHFSRTTRNAIRIEGDLIAAHMLGVRNILI
LSGDDPRVGTYPFSSSVEDFTIYDVFRLTKLLNEKNEDLAGVRVYGKFEFCSGGVFSPLE
SDYRQTLERMKGKVEAGCRFFISQPAFSQEATINFLERMGDLRGKSKIKIYVALMLFETC
SQLEHFSKVPGVFVPNEYFRYRSDQNLKRFSLKRAILMVEKLSPYVDGFYLTSTTKDLEL
IKTIGDVVLDSYQD
>A0A2V4V049|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PP-F2F-G20b|TrEMBL
MSTRTLYPAERGDLRLSFEYFPPKSDEMDAQLTRTAAALNAYAPEFVSVTYGAGGSTKAR
SLTTVRRLLDDCAIPGTAAHLTCVGATRAEVDAVVEEFAAAGVRHFVALRGDPQGGIGAQ
YQPFPDGYENAAALVAALARSGRFQISVSAYPEKHPESSDVDADIDMLKRKVDNGATRAL
TQFFFDNNDFERYLERVRKAGISIPVVPGILPINQFGQVSKFAALCGARIPEALSARLAH
LDESPEERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFKRTDDAAVE
GAAA
>D3F985|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Conexibacter woesei (strain DSM 14684 / CIP 108061 / JCM 11494 / NBRC 100937 / ID131577)|TrEMBL
MNLIRRIEAGQGEFLVFALTPPRLATEREQVQDIANTTIARLLPLDLDGLILYDIDDETE
RNPAERPFPFMPTLDPAHYLAEHLAAWPAPVVVYRAVSKYAPAELRSWLTAQDPRRVMTV
LVGAPSSATAGRTSLADAQALRRDTNPAVSLGGVAIPERHTRREDEHLRLLAKQEAGCRF
FVTQVVYDVNAAKNLVSDYHYECRARGMPPVPFVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLAHATDPLEASYEQALTTATELMAYCRTLGVPFGINVESVSIRRVEIEASVRLAEQL
RAHLH
>A0A3P3GAB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium tamadayense|TrEMBL
MNQFRFSRHPDIGDKVRVSFEFFPPKTEDMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNQTTLTPAAHMTCVDAARHQVDGVIQEFAGMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSREAEAA
GSAAA
>A0A2W6PQM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SW4|TrEMBL
MTTFSFEFFPPKTEKGERTLWEAIRRVEALRPDFVSVTYGAGGSSRDRTIAVTRRIAAET
TLRPVAHLTAVGHSAAELRRIIGQYADAGIRDVLALRGDPPGDPNAPWVPHPEGFTHARE
LVELVRSLGDFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFHVEDYLRL
RDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSGAAFPEDLAHRLEAARDDPAAGHRIGV
DHATAMAERLLAEGAPGLHYITLNRSTAALDIHRNVQTLGSLSAH
>A0A8H5G4S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucoagaricus leucothites|TrEMBL
MKFTTKFAAQPQSRPFFTFEFFPPRTDQGFDNLVSRISRLATLKPLGVSVTWGAGGSTKD
RSIELANLIQNEYGLDTLLHLTCTNAEVGSVDTVLDEATKRGIQNILALRGDPPRGQEEW
IPSDPRFTHAVDLVKYIRETHGNNFCIGVAAYPDGHPDQIVDVDKELENLKAKVDAGADF
IITQLFYDVDGFLSWLRKVRQKGITVPVIPGVMPIQTYGSFQRLTKLTGAKVPVHVQEAL
GPISHDDQLVKDYGVTLAVEMIRRLVSEGNVPGVHFCTLNLEKSVQRVLETLQWTGTSAH
PHNRLIADAPDEPTSDGDSDLLVTATTATQDATHSLASITVTDGEAGRGELNNAASWDDF
PNGRFGDFKSPAFGVEDPWGNSGVAINEMLRQWRHPKTLQELTQIFLDHLESRISTTPFS
PVPLSSESLMILPELKELTQRGWWTVGSQPAMNGVSSSDEVVGWGPKAGYVFQKGFVEFF
CEEADLELLERRIEERGQGWVHYIAGNYKVRVNLHPDVESVVLTFFVPRKSGFRTNVPED
GRNAVTWGVFPGQEIIQTTIIEHESFLSWKATPIYHFSPDSKAEFCYRKKHFLSGLIGHR
VTAQAQMSVISWKVYATGGG
>A0A8I1I125|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium tuberculostearicum|TrEMBL
MSPRLSASAPLDYESEEEAHAPERLALSFEVIPPRHDADAAKIDRLLEVLESYHPDYIAV
TSSQRSGWLEGTAAFIEKISQNTSMRPLAHLACTAGTRDELIGWINRLVDAGVRGLLALR
GDLPEGGMPEHYLQHADELVRLIRQLESHQAARFAAGRLAVSVACYPSGHAESKNEDEDF
DVLLNKQRLGADFAITQLFFDAEDFLRFAQRAKLAGVKIPLIPGIMPMTSLRRLERMGQL
SGLTVPERVRTQLAAATTPEEEYEIGMELTAQLARTIVAGGADGLHIYTHNNPDITQDLL
SRIGVDNDDH
>A0A0V1MUP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella papuae|TrEMBL
LMASLEAVELKTTRHDLNSSPKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTPEGL
INLLNRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCVLNFCLLDTMLHITSVQY
NEKTVLSNLERVKKIGIRNILALRGDINDDANVTATDFQYACQLVQFIRSHYGDYFTICV
AEDLLNLKAKVDAGADFIITQLFFNEMHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMK
IVQLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVELCRKLLNAEQHVVPGLHFYTLNQ
EKSTRQKHTLLE
>A0A7Z0HZE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhabdonatronobacter sediminivivens|TrEMBL
MSQPRVSFEFFPPKSLEASFRLWDTVRMLAPLGPDFVSVTYGAGGTTRQLTHEAVTTIGR
EFGLNVAAHLTCVDASRAETLEIAQSYAKAGVREIVALRGDPPKDAGGFTPHPEGFADSV
ELIEALAATGDFHLRVGAYPEPHPESADTAADVAWLQRKFGAGADSAITQFFFEPETFLR
FRDACARAGIDKPVIPGIIPIENWTGISKFARACGASIPGWMDDAFAKATRDGREDLLAT
ALCTELCDRLLREGVDQLHFYTLNRAHLTRDVCHALGLVPQVQLEKVA
>A0A8E2BB60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter lissarensis|TrEMBL
MTPPRPRQPDEHPDGIELPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRVMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPYDFRPVHLGKKIAAGAQFVQSQYCFDVPMFRTFMNRVRDLGYDEKCY
ILVGVGPLASAKTAKWIRANVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEISG
VSGVHVMAYRQEEYVAEIVDESGVLKGRRPWKREARSDDQRVAERLEHILHDDVTESQVD
MVKTAH
>A0A3N1XRW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobilisporobacter senegalensis|TrEMBL
MKIRDYLNKYKLIIDGAMGTYYAELENNENAISELANITAPKKIESIHREYIKAGAKLIR
TNTFAASKEVLHMDREELKDMIRSAYHIAKAAVIAEEADGANTRHQVYIAGDIGPIPENA
LSDEEEILLEYQLMVDVFLEEKAEVILFETFSDLKYIIPLVKYIKGKDKEVFIITNFCIN
KNGYTTSGFSARKLLEDLSSIDEIDACGFNCGIGSGHMFENLKKLPFPENKYIVSMPNAG
YPEQLQNRMIFTDNVNYFEGNLRQIAELGTDMIGGCCGTTPEYIKALHEHIDLAGTGRGV
RVSFTQKDNGYKELYSNAFYDLFSTGRKVIAVELDPPYDANYDKMIQCAHDIKKSGADII
TIADSPMGRSRADSILMSIRIGKEVGIPVMPHVCCRDRNMIAMRSSLLGAYINDVRNLLV
VTGDPVPTVSRVSTTGVFDYNSIQLMNFIKEMNEEHFIEAPIYYGGALNYGRGSIDKVIE
RMQRKIDGGAKYFLTQPIYSEKDIERIAYIKERIDTKILCGIMPLVSYRNANFIKNEITG
INIPDEIITRYHPDMTKEEAENVGASIANEIIEKLSSFADGYYFMLPFNRTSLLDKIIIK
>A0A8J5H5Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MEQAWTGCLRANAGSANFVIDKSDDAVFIAFSRAQAAASPSGFGRGCFEPISLYSSTHKL
FAPLGRGEEDSGGKPQPVLLQVLEDLRLTMDLFIDLCILSGCDYCDSIKVLDFEFPVVMI
NFVGFHISRGEFILRKNIFVCMETIMHLTCTNMPVEKIDHALNTIKANGIQNVLALKGDP
PHGQDKFVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPKAHPDMIQGDEGATLEAYNS
DLAYLKRKVGNS
>A0A8J5FPW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MKVIDKIRGAANGDGRTAFSFEFFPPKTEEGVENLFDRMDRMVAHNPSFCDITWGAGGST
ADLTLDISNRMQNMKVMYPVYIDLLNSDIDLESALPDRAITKSVLVFDSIDSFMQICVET
MMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHGQDKFVQVAGGFACALDLVQHI
RAKYGDYFGITVAGYPEAHPDMIQDGIATEEAYNSDLTYLKRKVDAGADLIITQLFYDTD
IFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPDKITNALEPIKDNEEAV
RAYGIHLGTEMCKKILANGINTLHLYTLNMEKSALAIIMNLGLIEESKVLRSLPWRRPTN
VFRVQEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSNNPSYGALTDYQVISMPITNLV
LALSGLGQSGRQSLPKPEWENSTVDFQSGRGKLPECRVGPEMHC
>A0A5F2HVK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1D.F.Ca.ET.183.01.1.1|TrEMBL
ALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAAGSAAA
>A0A2W6U281|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MHSLPNNITAGYSLEVGAKAIPALTAAAARIALGSTIFIPYLPGEDNAARLAAAATVREL
GFEPQLHIPARRIASFAELESFIARAVHEAGVERCFVIAGDSPSPKGPFADSASLIETGV
LERSGIKLVGVAGHPEGHPVMSESQRWQVLERKCSSIENRGMAPLIVTQFGFDADIVLRW
LAALRERGIGQPVRVGVPGPAGIAVLARYAAMCGVSASASIWSKYGISIGKLFGTAGPDR
FVDRLASGLTEAHGTVSLHIFPFGGIDQSLEWVEHYRNQR
>A0A1G1ISP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica bacterium GWA2_41_15|TrEMBL
MALCEKIKSGKFIITSEIAPPKGTDVEEILKDAELVRGRVDAINVTDLQSSVMRTGSLAM
CKLLIERGLEPVFQITCRDRNRLALQSDLLSAAVFGIQNVLALTGDHPALGDHPGAKPVF
DLDSMQLLEAIRGLQSGKDMAGKELKGSPKFCVGAVVNPGADPIEPEIIKMEKKIDSGAQ
FFQTQAIYEMHLFEKFLKASSHLKTTIIAGIVLLKSAGMARYMNKNVAGVFVPEDLIQEM
EQTKDKSAKSIEIAARLIKELKPMCQGVHVMPIGWDKKVPLVLDAAGL
>A0A0M5LXM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter alpinus|TrEMBL
MLPTRLEIIPTQGVIPAVLAKVPTSTTLTVTCLPHHGVERTMETAVALAGHGFTVVPHLA
ARAIGSREQLARLIRSAAGAGIAEIFAIGGDTAVPAGPYSSSESLMREIVELSGRTIKLG
VAGYPEGHPSISRLQLMESLQAKAELADHVVTQMCFSVPTIAEYIAGLRSEGVLLPVWAG
VAGSAPRTKLVFLATKIGVGSSLRFITGKGALGRQLLSGSRYQPGALIRDLTSLPKPPDG
IHLYTFNALDAVDSRP
>A0A3D3Z3D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium|TrEMBL
MSQPTISFEFFPPKSEAMEAKLWDAVSRLAPLSPDFVSVTYGAGGSTRERTHRTVKRILD
ETSLQPAAHLTCVAASKAEVDEVLREYWAAGVRHIVALRGDPPTGVGTAFEPHPDGYVNA
TEVTAAARRIADFDVSVSFYPEKHPESPSLQHDIDVLKAKIDSGATRAISQFFCEADVYL
RFRDAAAKAGITIPLLPGIMPVGNVAGYTRMATSTGTSIPAWFAEAFDGLDQSPEVRDMV
AASVAADLCLKLQAEGVDRFHFYTLNRAELSLATCRRLGLKTPVTEKDAA
>A0A4P7JGR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boseongicola sp. CCM32|TrEMBL
MTVPSVSFEFFPPQSLEASFRLWDTLGVLAPLAPEFVSVTYGAGGTTRKLTHEAVKAIDT
NFGVPVAAHLTCVDATRAETLAIADSYAEAGVTQIVALRGDPPKGTGGFTPHKDGFASSV
DLIEALARTGKFTLRVGAYPDPHPDAPDMAACVAFLKRKIDAGASSAITQFFFEAETFFR
FRDACAAAGITAPIIPGILPIHNWARIRRFASSCGAVIPAWLDEAFTAAKRDGREALLST
ALCSELCTDLIEGGVSDLHFYTLNAPELTRDVCAALGVTPKQALAEVA
>S1NUC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli KTE182|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>N9EIA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bereziniae LMG 1003 = CIP 70.12|TrEMBL
MSKRIPISFEFFPTKTDAGAEKLKIVHQELQQFNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGDHFKIEVAAYPEMHPQAESYDADIQHFIEKVNAGANAAITQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIEGGAPSLHFYTMNHTEPNRQLVLDLGLA
>G8NVM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8)|TrEMBL
MAVGIDRLFAGGTVLCDGAMGTMLYSCGVFINRCYDELNLSQPEMVRSVHQQYLQAGAEV
IETNTFGANSFRLERFALREKVREFNLAGAAIARQSVDAIREKQGTEAFVAGAVGPLGVR
LEPLGKLSLEEAREAFAEQISALAEGGVDLIIIETMMSIDEAEQAVLAARQVAPHLKVAV
MVTVDEDGNCLDGTSPEVAAERLTAVGADAIGCNCSSGPATVLTVIERMREATALPLLAM
PNAGMPRNVEGRNIYLTSPEYMASFVRKAVRAGASWVGGCCGTTPAHIRAMRGSLRAMDA
QESGERATEHTPHIVHASESEHRVEPRPLGERSQIGRMIADGEFVTMVEIVPPKGFDCSK
ELAGALLMKKRGVHVINVPDSPRASARMGAQSLCVQIQQQVGIETILHYTCRDRNVLSMQ
SDLLGASSIGLKNILCLTGDPPKMGNYPDATAVFDVDAIGLVNIVHGLNQGLDIGRNPIG
GSTGFTISVAANPGVPDIEHEVRRFAYKVEAGAEFCITQPVFDLRLLEDFLRRIEGFRIP
VIAGIWPLTSLRNAEFMKNDLRVAMPDEIFVRMAAAGGKEEALAEGLKIAQEMLASVRGS
VQGVQVSAPFGKYTAAAEVLGLTEEIA
>A0A832SDD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurococcaceae archaeon|TrEMBL
MRVICPKKMLNGPCGGVRGELCEVDDFKCPFVEAFRNLRSSEYLKPLLDPGFKVGCEVVE
VEPSPYVKKLEDFAVSAEVEPWGPEELERASKWRVDALNVTDNPLGLPHLDSVWASAALA
SKGKEVIAQLTCRGRTREALASSLLALDASGVNNVLALTGDWAPNAAFDLDAVRLVCLVQ
ALRKGVDWEGRKTRRVRLSVGVASNPYFSYEEKRLLRKAHAGAQFAQTQPVFKKELLYKI
KKYPLPTVPSLLLTTSRKVVRALMERGVDAKEFYEELVKAKREGKADELVLKKSLEMYEE
AYSSELPGVHLMAPGRPDLLERFLELLRL
>A0A8H5RDA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sp. NRRL 52700|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFEATLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIEVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINSRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLVQLNLKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPTNEWDTLKAKLTSPELQDSVCFYASNASGDYLASDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWKLLLS
>A0A7W9TQN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Castellaniella defragrans|TrEMBL
MELQAAPSQVLEEAASGLSDYSLEVTAGGVDQAQAAVRALRPGTAFSITFLPGEDYPARL
RAAQVLRSLGFVPVPHLSARRMAGVREAESFIEALAVSAAVDRVFVVGGDPDRPLGPFRD
ALDLIETGLLERHGIREVGIGGYPEGHPAIPSDRLWAALQAKCEAIEARGMRPFIVTQFG
FEPGVIVEWLTEVRRRGIRCPVRVGVAGPAKIATLMRYAARCGVSASARAMSRYGLSLTR
MIRSAGPGGLIADLAAGLHAAGIRDVGLHYYTFGGFQQTIDWIRSFHEAQHG
>A0A194PN72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Papilio xuthus|TrEMBL
MSELLKISDLIRNKRSFTFSFEVTPDVGEAELDKITLQPEFYSITWHALSHQYSFNANRS
DFKTSSEMISYIRAKTSDYFCIGVAGFPYDDCKITALKEKIDLGADFVISQAFFESNVYK
NYLEKCKDAKIDVPIIPGIFPFQSQKELDMFLKLCKVKVTEEFRMKLEEKSENVMDIIEN
LVLDLRNNLNVKHFHFFTINKLGITCELVKNIQLSL
>E3CXR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminomonas paucivorans DSM 12260|TrEMBL
MHLRDLFRAKKPVVSFEIFPPKAGTPVEGIYATLGAIRDLNPDFVSVTYGAGGSTKDLTR
DIASTVKNRFGLEVMAHFTGLAHTPAEVDEMAEDLMDEGVCNVLAMRGDPPLDGVLPPNP
AFPHAADLIRHLRRGFGDDLSIAAAAYPEGHLECPDPEQDLLHLKAKVDEGVDFLVTQLF
FDNELFYRFVEKVRALGVTVPICAGVFPVLNPKQVQRILSLCGVAFPPRFARILARYADD
PAALAEAGIAYATDQIIDLLSWGVEGIHLYTMNRPETTRRIMDNIGLVRRSLVDRNEGEA
S
>A0A1V5G3Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.BinA261|TrEMBL
MSVSELINSNAGKTAFSFELLPPLKGNSIRHVFTTIDRLKEFDPKYINITTHHSENIYKE
GDDGVIRKINIRKRPGTVAIAAAIQNKYGITAVPHLIAKGFTKEETEYSLIDLSFLGVTD
LLLLRGDTNKLDIEQRKMDSHEHATDLQIQVNNFNKGIGYDGTRFEAPENPFSYGMACYP
EKHEESPNMESEIYYTKMKVDNGAEYLVTQMFFDNRKYFDFVDRCRAAGITVPIIPGVKP
IHLMSQLTVLPKVFRSDIPEDLARELRKCTTDDEAKEVGVEWCIAQCKELIRHGVPSIHF
YSLMATESVYRVAKEIY
>G3XLM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a / NRRL 328 / USDA 3528.7)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDGQDPARDLPYL
IEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPHVLSKLEEVKHDDDAVKRIGVDIITDLVHGIRDLVSPGLRGFHFYTLNLEKT
VSFILERCELIPPYTEIDDSDALADGGNLSALDSSSYIAPNGAPIRTLASRRSSVSSIPH
NRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEEDSNGLNAETAIIQPELLTLIDKKGWWTLASQPAINGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNTDDPDPIDIN
PANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDDTK
NDVWLVCVVGQEFGAGTEPGSEEEEDEKKWMWRELANSQ
>A0A2I1RBP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia terrae|TrEMBL
MRPAPYTVRVTPTAPAPSIVERLAAPHRGPVPFSVEFFPPRDAEAESRLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSVAELRALVGAYADQGIT
NILALRGDPPGDPLGEWVAHPDGVEYAEQLVRLIDTLGDFHVGVASFPETHHRSPDIDHD
TRTLVDKLRAGAEYSITQMFFDVEHYLRLRDRVAAADPEQGLKPIIPGIMPVTSLATARR
MVELSGSVIPPDVEERFAKAAGNGAEEDRASVRAVGIDFATEMAQRLVAEGAPCLHFCSL
NFAKATTEVLGRLGVDVDAALHVPA
>A0A1H3HQY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus africanus|TrEMBL
MQPRPDTGGSVSSLSMTRTVRELLAEGRPTWSFEFFPPKTPEGATQLWTALRELERLHPS
FVSVTYGAGGSTREGTVSVTERIATETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNL
LALRGDPPGADPQAEWVAHPEGLTYAAELVELIRSMGEFSVGVAAFPERHPRSPDFETDV
EMFVRKCRAGADFAITQMFFRPEDYLRLRDRVAATGCEVPIIAGVMPVTNARQITRIVQL
SGQAFPEHLAARFAELDGDTPEARAAVRAYGVEVATELCRTLLDEGVPGIHFITMNRSTA
TREVHANLAAVGSPH
>A0A373VA32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF19-15|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A2G2LNP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp|TrEMBL
MTKQLTISCEFFPPKSDKGIAILRDVREKLAPLKPEFYSVTFGAGGSTQENTLDAVIDIQ
QANVTTGIDAAPHLSCVGSTEDNIRNLLHTFKQNNITRIVALRGDLPSGMRDPGDFRYAN
ELIEFIRKETGDHFTIEVACYPEVHPQADSAQADLDNFKRKVDAGADSALTQYFYNVDSY
LYFVERCQKAGIEIPIIPGIMPINNFSQLARFSDGCGAEIPRWLRKRLEGFHDDTESLQA
FTLDFLTGFTEKLIAKGVPGLHFYTMNRVDPTLTICQRLGLVD
>A0A0Q6SBT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Root1212|TrEMBL
MAHIDENPLGRHLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPDDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VTNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNSKFLSGRKLTTPPQVFLGA
AINPFAPPYDFRPLRLAKKIEAGAQFVQSQYCFDVPMFKRYMNRVRDLGLDEKCYILVGV
GPMASAKTANWIRNNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIKGVSGIH
VMAYRQEEYVAEIVHDSGVLKGRTPWKRERNPGDDTVQQRIEELKDGKTENQEQMAETAA
HHPH
>A0A086PB25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium herbicidovorans (strain ATCC 700291 / DSM 11019 / NBRC 16415 / MH)|TrEMBL
MTLSFPSVEEAARAWQAPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFV
SVTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKAEIDEVVDAYWDAGVRHIVA
LRGDPPEAGKHFEPHPEGYKGAAELVEGLRKRHPFEISVAAYPETHPDAASAQSDIDNLK
RKLDAGASRAITQFFFEPETFFRFRDTVAAAGIDAEIIPGIMPVSNFAAVQRMSAMCNTD
VPGWMGKLFEGLDDLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPA
>A0A3R9V3Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC07061|TrEMBL
MALGTASTWSDRAHTVRDLLASGTSYSFEFWAPKTEKGERNLWNALRRIEAVSPSFVSVT
YGAGGSTRGGTVRATQQIASDTTLTPVAHLTAVDHSVAELRHVIGQFADAGIRNMLALRG
DPPGDPMGPWVRHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVAKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
DAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A1N7BCC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. A214|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRSLLSQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGEHFHIEVAAYPEMHPQARNFEDDLLNFVRKANAGANSAITQYFFNADSYFY
FVDRVRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A7S8XNG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. TTH0-4|TrEMBL
MTKRVPFSFEFFPTKTDIGAEKLRVVHQELQLLKPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFKIEVAAYPEMHPQAETFDKDIQHFVEKVKAGANAAITQFFFNPDAYFYFI
DRLAKQAIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVLKLSERLIAGGAPSLHFYTMNHTEPNRQLILDLGLA
>A0A7Z2PUP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. CCBAU 051011|TrEMBL
MTVPDQSSPRLAALLPSASVEISSRGHQLAELRDYFAAGTDVTVTFLPGDNYHHNVETAA
ALRSAGYNPVPHIAAREMASREALDDFLARARGEAAVSRVLLIAGDVVAGKGPFKSTGDI
RNSGLIEANGITSVSLAGHPEGHPYLELPDALNGLKGWREWGRRTGARVDIVTQFCFEST
PILQWIAELDRAGIDLPVIVGLAGPATPATLTKFALRCGIGNSMRALRAQVGRFGRLLTD
TGPDDVVRGLRSVPAAATASIAGFHLFPFGGLRKAGVWLRDYEHGPLQHVERAAISHLGL
QNP
>A0A7M2C434|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenarthrobacter sp. YJN-5|TrEMBL
MSPPSLTDTHSNLSAATAPVALSYELFPPRSPKAAETLWTTIRELEATDPDYVSVTYGAS
GSNRDTAVDLINRLLLETTLRPLAHLTCVGNTPAELADIVAELLDHGVRGILALRGDLPQ
DGTPPPSGSLRYAQDLIELIRRVEQRRTALLCAGKIAVGVAAYPAKHPESPSVEHDVEVL
LAKQRSGADFAITQVFFQAHEYSNLVSRARRAGVTIPIIPGVMPFTSLRRLKRLGELAGV
DPSAHLMDRLAAADTEAEQRRIGVAATVDLANAALDAGAPGIHLYTFNEHAHALDVLDKL
ALPRPARPTFRTQPVSRTPEPVRHEEFAI
>R8MNL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus (strain VD146)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTSIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPNFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A3P1B9G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Larkinella rosea|TrEMBL
MAKVSDHIRQANGKTIFSIEVIPPIKGDNLKNLLDNIEPLMEFRPPFIDVTYHREEYIER
PEPDGTIKKIVTRKRPGTVGICAAILHRFGVDPVPHVLCGGFTKDETEDFLIDLNYLGID
NVLVLRGDPAKPFDTFKPKTNGYSYASELVRQVANMNRGIYLHEGETPMTPSNFCIGVAA
YPEKHFEAIDHDTDFNYLKLKIENGADYIVTQMFFDNRKYFDFVKRCRQEGITVPIIPGL
KPLTTRRQLQVLPRLFHLEMPSDFVKAVEACENDTQARQVGIEWCIQQSRELTKAGVPGL
HFYTMGKSDNIVKIAQAVF
>A0A447C276|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Podospora comata|TrEMBL
MGEFLPSLELPVEAGKNHAMDKITDKIAALPAETNYCSLEFFPPKTAMGFSNLRDRLDRM
ARALRPLFVNVTWGAGGSTATKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKTLEDAK
ALGIRNILALRGDPPRRAEYRDSNEPQTDDDEEDEFHWAVDLVRYIRKTHGDYFCIGVAA
YPEGHADESHPLGQSLEHDLPYLVEKVQAGADFLMTQLFFDIAAYDHFEKTLREHPSGAF
KDIVIIPGLMPIQSYQMIKRTTKLSHAKIPDALMDRLEAVRGDDERVKEVGVDIVSELVE
QIKEIKGRTAEGPKGFHFYTLNLEKAVSFIVERTGLIPPETPEEEELQSAVRHNPLPDIR
LLRINGSVPDDGRRKGSIGSDPRDRVIVQGRSTSYPDWEATAQEASIPAEPINSRANTLA
ISEGEGVLGREATWDDFPNGRWGDARSPAYGQIDGYGVSLHVTVAQALRIWGTPRTTEDI
NNVFIRHLKGELTNIPWSEEGFSPETDKIRDQLIKLNSKGWWSLASQPAVNGLRSSDPTF
GWGPANGFVFQKAFVEFFIPSADWKVLEQKLRHPDLKDDVCFYAINAAGDFVSSDAAGSL
EAEGEKEASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWGEWAKIYGKGSESEK
LLEKIRGDSWLVNIIHHDFIDSDAIWKVLLN
>A0A1H4QPC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter woluwensis|TrEMBL
MSPPSLIDRPLQQQGTTPVALSYELFPPRSQAAEEVLWATIRELETTAPDYVSVTYGASG
SNHDTALDLVARLQEETLLRPLAHLTCVGNTAAELAGIVAQLLDHGVRGILALRGDLPRD
GSPLPEGSLHYAQDLVELIRRVEQSRSALLCAGKVAIGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHARQYEDLLVRARRAGVTIPIIPGVMPLTSLRRVTRLSELSGVA
PDPALMHALETAGSELEAQRIGVAATAELANAALDSGAPGLHLYTFNEHRHALDVLDRLN
LPRPSRPLHERAALAS
>A0A267TK65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flectobacillus sp. BAB-3569|TrEMBL
MTKITQYIEEAKGKTLFSIEIIPPVKGESIQTLMNNIEPLMEFQPPFIEVTYHREEFIEK
VINGRIEKIPTRKRPGTVGICASIMNRFKVDAVPHVICGGFTQEETEDFLFDLHYIGIDN
VLVLRGDPVKGNAAFVPEKGGHAYASELLEQVVSMNQGKLLHEETESTPTNFCIGVAGYP
EKHFEAPNFQVDFEYLRRKVALGADYIVTQMFFDNQKYFDFVKKCREEGINVPIIPGLKP
LATRKQLTVLPRIFHLDIPIDLVNAVNACKSDKDVKQVGIEWCIQQCKELMDFGAPILHF
YTMSKSESTQKIAQAIF
>A0A2L0H5J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium fredii|TrEMBL
MSPDINPFDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHEATPTETLVAERLEHLRGGIEENQQQMAEAAAH
HPH
>A0A8D2ZR01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scophthalmus maximus|TrEMBL
MVNQAPRGEGSWSDSSGASNSGGESSKESSRSSTPVLDADRSDRLRDKMRRRMESADRWF
SLEFFPPRTTSGAVNLLSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYC
GLESVLHLTCCNQTREIITGHLAKAKHLGLKNIMALRGDPVGADWEEEDGGFNYAIDLVK
HIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVITQLFFRSDTFLKFL
DDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITNVIEPIKDNDAAIRNYGIH
QAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVE
DVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLHM
WGEELMKEESVFEVFTCYITAQPNCSGQKVMCLPWNDEPLAPETNLMKDELEKVNRRGVL
TINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHI
VNVHGRNLTNALDFQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYE
DESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIEDMFEMLDAPPEPV
>A0A2A7AIJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MKDIRELLQTRPLLFDGAMGTYYKAAPGVECEQANLTDPAGVLAVHREYLAAGADAVKTN
TFSLPRLAAAHTPGWEQLAQAGWQLAVQAAEETGAAVFADLGPAPDTEAVPAGQVYTAVA
KQFAALGARNFLFETLSSDAGLLDAVGAIKAEVPDAFVLVSFAVLPDGYTREGMYCKDLA
RRMQESGIVDAVGLNCVSAPGAMRTLAKQLGGTLPLSVMPNAGYPVVTRTQVKYQGRPEY
FARELGRLAAEGTVQILGGCCGTTPAHIAALRAELDRLPVVEKTAPAEEFSTVKEQTVEN
EDAFLRKLNAGEKVIAIELDSPRNADLTGYLEGAKKLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGLCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPGPMTVFGALNLNARNFDVELRRAKEKLENGMSGFL
TQPVLSAQAVENLKKSRETLGADAKILAGIMPVVSQRNAIFMENEINGIHVEDWIIEKFA
GLDRAQGEELGLAISLEMAKAALPYADGLYLMTPFNRVALMERLIGRLKQEVLGAY
>A0A7Z1LGP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hodgkinia cicadicola|TrEMBL
MINQTSVSFVAANSIYVRFSVEYLPPRKISNLSKMLTSNPNSNQIKLLEFNSITCNSENK
NRLNPTTLLLIRLRRLCNCSIILHNFLTQIKCMLISDTSMLHDLGVNNILLISGNKYTTN
KNRSDDISPYRIRRILREKHIFNIGADYPSNHILYSGSFQDLFTMLLNRESGCSMHITQI
FNHMDNFLRNNLRCSIFKLGSLLPGLFISSKHPLAVDINLKYGIYLTRQVKELLESEYLD
ERAAFLFNMYRIIEIIKNDITWIQVFTLNKTRILKEIIWVLNDLTYYIRYWRLRTRNECY
AAMCDMHNAYKRR
>A0A7Z1LH42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hodgkinia cicadicola|TrEMBL
MINQTSVSFVAANSIYVRFSVEYFPPRKIYNLSKMLKSDLNSNQTRLSEFNSITCNSENK
NRLNPITLLFVFLRRLCNCSIILHNFFTQIKCMLISDTSMLHDLGVNNMLLISGDKYATN
KKRSDDISPYKIRRLLREKNVFNIGTGYPDNHILCSGSFQDLFTMLLNRESGCSMHITQI
FNHMDNFLRNNLRCSIFKLGSLLPGLFISSKHPLAVDINLKCGIYLTRQVKELLESEYLD
ERVAFLFNMYRIIEIIKNDITWIQVFTLNKTRILKEIIWMLNDLTYYIRYWRLRTRNECY
AVMCDMHNAYKRR
>A0A4R0ECN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter terrestris|TrEMBL
MLKGASSTQISICNSARDIADFEQFLHQAKTQGINNLLLLTGDKLKQHQSGTKNIERTRY
LESVNAVMAAKHKGGFCIGVAFNPFKYAEAERDAQYFKLHKKIKAGADFIISQLGYDLDA
LKQAQLFLKEHQYRQSIMTCIMPLSLGRAKYMVKHQVAGTVITQHMLNVLEQEKQQGKTN
HIYLRCALQILICQHLGFGGVHLSACYKPEDQMLLAKYIEKYRHLSLVECESLWNDHWQI
KTGKEFHPVLENDSISVTSMQILKYRNLKFMHDALFQSSVARGIGFFIFKAQFWNRSLSM
KALLKTEFISKHHIVGCESCGLCRLADTLYICPETCPKGLANGPCGGTYLDRCEFGDREC
IHSVKARLAKAVKQTEILKNKLIPSVPIELRGTSSWKNWYLMKDA
>A0A7X1G0E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium piscinae|TrEMBL
MTVLPSYPLFADLPGDISVSFEFFPPKSEKMEEQLWDAITQLAPLDPSFVSVTYGAGGST
RERTHATVARLVRETSLVPAAHLTCVSASKDEIAEIADQYWAAGVRHIVALRGDPPPADG
GRFVPHPAGYASAAELVAGLRARHAFEISVAAYPEVHPEAVSTAADLDNLKRKVDAGATR
AITQFFFSTDAYFRFLDKVLAAGIDVAVLPGIMPVTSFAAIRRMSANTEIPGWMEAMFEG
LDERPGPRSLVSAVAAADLCRRLYAGGVRDFHFYTLNKAEQAYAICHLLGVRPKG
>A0A329TJL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MTDIREYLARKPLLFDGGMGTYYKAAPGADCEMANLTDPEGVKKVHAEYLAAGAQAIKTN
TFGLPRMAAAQMPGWEELAEAGWKLACDAAAEKDAAVFADLGPAPDTEAAPASSAYGLVA
QQFAALGAKNFLFETLSSDVGIVEAVKALRVAVPDAFVMVSFAVLPDGYTREGLLFRDLL
RRMEQSGVVDAVGLNCVSAPGAMKKLVQSLGETLLPLSVMPNAGYPVVTRARVLYQGKPA
YFAREMGQIAAAGVRILGGCCGTTPAHIAAMRAELDALPQQTEAAPAAKLSTGTAPTVEK
DDAFLRKLNAGEKVIAIELDSPRVADLSGYLDGARRLQAAGADLLTIADCPIAQARMDSS
LVACRIHRELGMCALPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSAMTVFGALNLNARNFDVELRRAVEKLENGMSGFL
TQPVLSAQAVENLRKARQTLGERAKILAGIMPVVSQRNAIFMENEINGIHVEEDVIQRFA
GLDREQGEALGLEVSMQMAREALPYADGFYLMTPFNRVALMERLIARLKTELLDAEG
>A0A1J9NL20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia catarinensis|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAAVATRTICERLVM
>A0A3B9APJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospirales bacterium|TrEMBL
MKVTEHIQKAKGKTLVSFEVLPPLKGGSMQAIFKTLDALMEFKPPFIDVTYHREEFIYKK
RPSGYYDKTAIRKRPGTVGICAAIMHRYGVDAVPHLICGGFSVEETENALIDLNFLGINN
VLALRGDARQFEDKFIPEEEGHKYALDLVRQIAGMNHGKYLDLNIQNGEPTDFCIGIAGY
PEKHFESPNMATDLHFTKEKVDAGAGYIVTQMFFDNSKYFEYVEACRAGGIEVPIVPGLK
PLTKKYQLNSIPRKFFINLPEDFVREVLKAKDDEAVKQVGIEWCMQQSKELKAAGVPCLH
YYTMGDTETVRKIAGVVV
>A0A2R5FAT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novimethylophilus kurashikiensis|TrEMBL
MTRLQRVYSFEFFPPKTPEGMAKLREARKQLAQLNPKFFSVTFGAGGSTRDRTLETVVEI
QSEGLEAAPHLSCISSTREEILAILEQYKSHGIRHIVALRGDLPSGEMSASDFRYANELV
EFIRSETGDYFEIEVAAYPEFHPEAPSAKVDFTNFKRKVDAGANAAITQYFYNADAYFRF
MEECDAAGIQIPVYPGIMPIYNFAQLSRFSAGCGAEIPRWLRLRMQDYGDDLASVRALGL
DVVTELCDRLLAGGAPGLHFYTMNQAGAISTLWQRLGL
>A0A4Q3A0A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium|TrEMBL
MKVTQYLAEANGPIISLEILPPTKGKSIDSIYSHLDPLMEFKPAFVNVTYHRAEQVYKKR
TDGTFERVEIRKRPGTVGICAAIMNKYKVEAIPHLICGGFSKDETENALIDLHFLGVKNV
LALRGDAAANEKFFSAHPNGHRYAEDLVKQIVSLNKGQYLEQDIIDGVKTDFCIGVAGYP
EKHFEAPNLDVDIDYLKRKVELGADYVTTQMFFENKHFYNYMDRCRQHGLNVPVVPGLKP
LTGKRQLTMIPSIFNVEIPVDLCNAMMKAKTEQECEKVGEEWLLQQCRDLLKNNVPVLHF
YTLGKPHVVYNVLKRLF
>A0A0X8CN77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. CCGE-LA001|TrEMBL
MTDVTTPATAEGHLRRPAISFEFFPPKTEEMERNLWDTINRLAPLDPKFVSVTYGAGGST
RERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPAGGIG
TPYCSHPDGYQSSAELVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKAKVDAGAT
RAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWFAAK
FDGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISHLLGIRAKSAQ
KAA
>A0A0A7MJV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus equuli subsp. equuli|TrEMBL
MSYAKEIDHLNQSVADLNGQINVSFEFFPPKNEKIETMLWDSIHRLKALKPKFVSVTYGA
NSGERTRTHSIVKNIQQETGILAAPHLTGIDASPEELRAIAQDYWDNGIRNIVALRGDEP
AGYTKKPFYAADLVRLLKEVADFDISVAAYPEVHPEAKSTQADLIYLKQKIEAGANRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKVTNVRIPSWMQKMYQGL
EDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A2A2URN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. HM-SA03|TrEMBL
MALTLQEKIIDPNQGVYLIGTTPPKIGTDPQQLKSIAAKLLGRLHEIEYDGVIIYDIQDE
SSRTQVPRPFPFKHTVDPCEYSQLIRELSHLDVITYKSVAQRDSEAFGDWLSSTKQQYGL
NNLVLVGSPSSQGDIKLPLSEAYKVLKHHQDDFFLGGVTIAERHASKRNEHERLVDKTEQ
GCQFFVSQAVYDAQATIDLITSYARTCKQQGQTPKRIILTFTPCGGEKTLQFMEWLGISV
PEATKWRMLDADNTLSESIRICRENLDQILKSCSHLDISLGLNIESLTNRKEEIDASINL
YRLLKATMELCLAEKQIA
>A0A5C8ZXQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parahaliea aestuarii|TrEMBL
MTKQKPRISFEFFPPKTPEGKQKLLQETVPALNALGPEFFSVTYGAGGTTRDSTRGIVTS
MREAGIDVAPHLSFGGDDEYAVGDLLDNYVNSGIKRLVALRGDMPSGMGASTQLVYANQL
VEFVRQRCGDHFEIEVAAYPEIHPESDSYDSDIKFLKQKLDAGANSAITQYFYNVESYFY
YLDRCADAGIDKPIYAGVMPITNFQNLARFSRNCGAEIPRWICRRMESYGNDQESVRKFG
LEVVTQLCQTLIDSGAPGIHFYTMNQVEPTREIYNNLGLK
>A0A359BA87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotomaculum sp|TrEMBL
MMKVIDIYSNATKPVFSIELSPPLNGTSLDPIFNTVSGLMKYEPAFVSVTCSALGSARGG
TIPIAGKIKRDYGIESVVHLTCVAKSQQDIDNMLMDVRYEGVQNILALRGDPPKGEKEFR
PHEKGHRYASDFVSQIKRLNQGKYISFNEGEYRNGEPNNFCVSVAGYPEGHPECPDKEKD
LEHLRVKVENGADYIITQLFFDPEIYFRFVDRVNNMGIRVPVVPGVMPVESFAHLDFILK
QPIGVSVPEVFVDKLRKYKEDGDNASALQFGVEFISSMCNALIEGGAPGIHMYTMNTPDR
AAKIFDAISR
>A0A095ZK99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium S5-A14a|TrEMBL
MTKIQNIKFPLVFDGAMGTYYPDKSKRVMPECEMANLFDSEVIYEIHKEYVDAGAMAIKT
NTFQANTVSLGTDFSVVKNVIEAGLSLAKKAVKNTETLVFADIGPIPGNDENSIDEEKEI
IDIFLENGINDFLFETFSEIGTLKELAKYIKEKDENAFIITSFAVGADGLTRTGEVGEDL
LNEAAKSADTDAVGFNCVSGPLSLREYIDKIDLPEKIISIMPNGGYPTVIKNRTYYSANK
DYFSNATLQFLEYGVQIIGGCCGTRPEFIREITDRISEYRYTKTRPTKKKHVRLETPYTE
NLFRNKLEHGKKPIVVEFDPPKDLNMKRYMENVKALSNSGADGITIADCPVARVRVDASL
TAYKIKNEIGIDPIVHMTCRDRNVNASKALLLGLNLENILNIITITGDPVPTAEKDEVKS
VFQFNSTKFAALVSDMNEKVFTNKMNIGGALNLNANKFDLEIKRAQAKEKAGVNVFYTQP
VISKAAVENLKIARRELKSYIMGGVMPIVSYKNALFMNSEASGIRLDDGIIEQYKDLERE
EASRLAVEITSDFMRQIEDYIDGYYIITPFSRVDIVGELIQLFKRK
>N1LM66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. GeD10|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A3N0ZCF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes/Chlorobi group bacterium Naka2016|TrEMBL
MKDFLSQLGERVLLFDGGMGTELYRRGIFINKCFEETNLSAPELVKQIHIDYINAGAQAI
ETNTFGANKFKLKRFNLQDKLYDIVLAGAKLAREVAGDKVFVAGSIGPLGVQIEPLGPIS
REEAQEYFSEVIKPLLDGGADLLIFETFINIDELRQAVISARKLTTIPVIAQITIDEYGN
TLTGTDPETTISELENIGADVIGVNCTVGPQTMLDWLERVRPLTSLPISIMPNAGKPKNV
DGRNIYLASPEYFAEYAKLFVRSGANIVGGCCGTNPEHIKKMSTAILALQPKITFQKIEK
ITLKEEPKVKTIEKKDKSRLARRLLQGHFVKFVELLSPRGVDPSKEINKARELFYNGIDV
INIPDGPRASARMSALALAVKIQREVGIETVLHFVCRDRNVIGIQSDLLGAYALGIRNIL
AITGDPPKLGTYPDATGVFDVDSIGLVNILTRLNNGLDIAGYPIGEPTGFFIGVGVNPLA
VNLDEELRRLYWKVDAGAEFIVTQPIFDVAGFKSFLKQIEHYRLPVIAGIWPLTSLRNAE
FMKNEVPGVVVPDEIIERMRKVADSKERSLEEGIAIARETISEIRHLIQGVQISAPFGRI
DAVMQTLEGME
>A0A7C6WKT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKIVDKFSTRNPMISFEIFPPKADYPVNTIYDTIDELYSLNPDFMSVTYGAGGTTKDKTV
EISSYIQNKYNLTSIAHVTCISSTKNEINNILSSLKDNNVHNVLALRGDFPKDADANVFP
ADGFRNSVELIEYFKSKSDLCVGAACYPEKHPDAKDLDADIDFLKRKVDVGADFLTTQMF
FDNEVFYDFHDKIEKKGINVPVIAGIMPLLSKKQIKTIKNLTGNSIPKKLIRILDKYEDN
PEALKEAGMSYAISQIIDLLSWGVDGIHIYTMNKPSTAKMILGSISAIRSVLTNESK
>A0A5P8NPA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas xiamenensis|TrEMBL
MFNELINKLKNDTYITLETTPGHSPVFSPIIDTIAELGLDKLVDGFTTTDNPLAKLKYNS
LFAAKMLQERFHKPVIATMSMRDRNKIALQSDLLGANEIDIRAILALTGDPASISDQPHT
KAVFEADSTLLLDIVSCFNSGIDYAGKPLTHKPKEIYPFAVVNSYAKNPKTLQKKMQKKI
KHGALGIITQPVYDLQNAKLLLELKEAANKECCNERKDAELILGIFPITKLRTAQFLSAH
VPGINVPDEWIEALKIANEQGPEEEYRVGFELSKNLFLEIKAFHPKIHLMTANQFQIARD
ILL
>A0A399INJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium chromiireducens|TrEMBL
MIKKYLQNNVLISDGAMGTYYSELTGNDASYCEFGNLNDKDTIKRIHTDYIKAGAKLIRT
NTFSANTYDLGVSFERLKDIIKSGVDIAKEAAIGNDVFIGASIGPIKELNLDESHSSILD
EYKFIVDCFLSSKINVFIFETFSNCNYLKEISEYIKSKDSSSFILTQFAVKPDGFTRDGL
SVGKIIKLIKNIQYLDAYGFNCGSGPNYISEIIKKINIGSDIVSALPNAGYPEIIHERTV
YPNNPAYFAKKVNEIKSLGVSIVGGCCGTNPNYIRQLASLIDDKSKKIKNIVKNEEEIKK
YENKTENAFKNKLDNNEFVVAIELSAPIDIDISKLIVGAKICKENNIDLVTVPDSPMSKV
RADSTIIAAKIKREIGIEAMPHICCRDKNTNAIRSSLIASHIENVRNVLAITGDPISDAS
KVETKSVFNLNSFRLMELIQDMNEEFFKEENILVGGALNLNVRNKEVEYNRMLKKIEKGA
KFFLTQPIYDDDAIEFLKKIKERTDIKILAGLLPVVSYRNAVFLNNELPGVTIPDKYIKM
FNEDMTKEEAQEVGVKITVEIGKKLKDFCDGLYFITPFNRVNMLVEIIKQIKG
>A0A372LJ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peribacillus glennii|TrEMBL
MNFRDELKKRILIGDGAMGTLLYSNGIDNCYEELNISHPDRIETIHTAYLEVGADILQSN
TYGANYYKLKRYGLEEDVSSINRKGIAIAKKAAKGKAFVCGTIGASRSIRKSDLELEEIK
RSFREQLYSQLMENPDGLLFETYYDLEELETVLKIARNETDLPIIANVSLHEIGYLQNGI
HLNEAFDRLQELGADAVGINCRLGPHHMIRSLEEVPLPERAYLSVYPNASLPDYVDGRLV
YEAVPEYFGSSALKMREQGARIIGGCCGTTPKHIEAVKKALGNLPPIKEKQIKARKIEVI
EITHNENTIALHEKAKTERTILVELDPPKKLGIEEFMAGAKALHNAGADSITLADNSLAT
PRISNAAIGTMLKKEIGTEPLIHITCRDRNLIGLQSHLMGLQTLGLNEILVVTGDPSKIG
DFPGATSVYDLSSFDLICLVKQFNEGLSYSGQSLGQRTNFKIAAAFNPNVRYLHKAVERM
EKKIACGAESFLTQPVYSVSQIEEVYEATKHLDTPVFIGIMPLTSSRNAEFIHNEVPGIK
LPDNVRKAMAAAGNDPDRARAEGVSIARELVNAAIEKFKGIYLITPFLRYEMTAELTGYV
RKVDNERFVEVTAYEQ
>A0A256ZQN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon ex4484_2|TrEMBL
MSKLSERLGRGFVYTSEIAPPKGADLRGFRKELEELKKIKGKLSGVNVVDIPGSILLMSS
LGGSIMVKQAGLEPVYQVACRDRNVLALEADLLTASAYGIRNILAITGDHPRCKSSDHPG
AKPVYDLDSTSLLCCMQEMNQGRDLAGNKLYGGTNFYPGAALTHTASPWEGEIHKTRKKL
EAGARFFQTQAVFDVGELKRFLDEYERQHGEDIHGKVIAGLVALYDAGIIEFLESIPNVI
IPSEIKNRIINSGNSFQESIHLILEQIDELRDEGLAGAHIMTAGNAKVLMEVFREIK
>A0A8H6EXG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dekkera bruxellensis|TrEMBL
MDLESTGVFRYAKDLIKHIKSKYGDHFCIGIAAYPEGHPEEHDISKTIKYLKEKQDAGGD
FIMTQMFYDVDIFIEWCKKCRASGITIPIIPGIMPISTYASFLRRAQWCEIHVPDHFLKR
LEPIKEDDSKVREEGVKLVAEMCRKLLESGYINHLHFYTMNLEKSTVMLLKQLGLVSKQQ
VVGMDTKPWRRSLNPTRSDENVRPIFWQNRKFSYIQRTADWDEFPNGRWGDSRSPAFGSI
ELCDHELIRHSPKKALNLWGTPSTIGELSSLIIKYLQGKLSCLPWSDGKVTSEIDLIKDA
LIDLNSRGVITINSQPSINCCPSADKVHGWGPKNGFVYQKQYLEFLVPTTSVNFITNKIN
ETNRDAGYSVLSYYSINSRGLLCSNVQSSSAINAVTWGCFPGEEITQPTIVEKISFIAWK
DEFFSILKKWISLFKKDHDVEGGKSIALIEMLIRDYTLMNIVDNDYVAEPNTRIFSVLKA
TFPLKQ
>A0A1V5CTP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdus sp. PtaU1.Bin050|TrEMBL
MLKNRFREILEKREQFVYTVELVPGRGSKGKTHDDVLDLANKASQGGLVHAMSITDNPGG
HPALTPGVLGVEIARMGIDPIVHFTCKDKNRNEIESILYGLDRIGIRNLLAMTGDFPLYG
FEGKTKPVFDLDSVQLLHLITKMNEGLQIDARAPGGGRILPPTRMFKGCAVSPFKQLESE
TLAQYFKLWKKVQAGADFVITQVGFDARKFDELLRYMHHLDIKVPVLGNVYILNFPVARV
MNRNVVPGCVVTDQLFRICEEESKAPDKGKAARLMRAAKLIAVLRGIGYNGVHIGGPNLK
YEDIEWVIGKSIELSGIWPSLIPEFDYPQHEGFYLYEKDSKTGLNTDNLTKRKSSPGKSP
GYALMRFFHHLVFAADAPFYKPACSFFKKVNGTRLEGVLTGLEYWIKFVSSGCRRCGDCA
LADIAFLCPQSQCPKFLLNGQCGGSSEGWCEVFPGKRRCIFVRAYDRLKAFGEEDSLRGE
YVRPRHWELDQTSSWANYFLGRDHNAEKRNGKPQERP
>A0A2M8JH97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. FEMGT703F|TrEMBL
MKVTQHIENANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEYKE
LPNGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKTETYFHPEKEGNAYASELVTQISNLNKGIYLDEDLKNSAKTNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNKKFFDFVDKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMAVVKAKDNDEVKQIGIEWCVAQSKELVAAGIPVLH
YYSMGKAENIKAIAQAVF
>A0A316SSW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprobacter sp|TrEMBL
MKVTDLINESKKTGFSFEVLPPLKGSSIDRVFKTVDALREFNPLYINITTHRSEYVYKDT
PDGLYRRISVRNRPGTVAMAAAIQHKYQINAVPHVICSGFSRSETEYALIDLNFLGICNL
LLLRGDKAKHENRFTPDADGHEHAIDLQGQVNNFNEGYFLDGTRMDLVRTPFSYGVAGYP
EKHDESPNPDEDLKWLKAKVDSGADYIVTQMFFDNAKYFDFVERCRAIGIHVPIIPGIKP
VVVCNQLTVLPKVFHVDMPDTLVTELRKCKDDAAAKEVGVEWCTLQAKELISRGVPSIHF
YSMMATESVRKVAKEIY
>A0A374TKV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. TF11-5AC|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFNTPSVAHLTCVGRSHADIVAKIDEYRSAGVENILALRGDLPTGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A354UVE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MGEVRPDEDAENGWQEERKMSVMESLSRHNTLSFEVFPPRTEAGRRELLEPDGVLDRLNR
ESPDFLCCSYGAGGADAGKNLEVLDAVVSTGRSQAMTQLTCAGNTAEGIREQLRSYHARG
VSCVMAIQGGEGRMSWGLSDEAELVKLIRREFGNEFLVAADGAPEGEPLGSSLEGEINRL
KAIQEVGADFLITRLCWDMDIFHIWLDGIRAAGITLPVMAGVAPVVDQAATIRTALATGG
CAIPEELCRLLSDYWIYPNPFVKDPFDAEVERKRTQFREAGAAYTVRQIRLYRRWGVDGI
HFLTQNRAEDVLAIARAARDTSF
>A0A1H0W2M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. ok909|TrEMBL
MSKEVAARVRLEVVPSADLLTQLPLAFDTPGSVSVTCLPHHGPVRTVEASTSLARLGYHT
VPHLAARSITSQTELHSLLRQLQDAGVSELFLVAGDRRTPAGPYSWSGQLLGAIKAYSPE
FSLGIAGYPEGHPELSQEQLMISLQAKAPLASSLVTQMCFSAQAISRYVRTIRNSDVKLP
VWVGVPGPVSIKKLVSMGARLGVGRSLKLARGTGMAGALWRGGDFNYDSAQLIRQVHHEL
GGDPLFAGVHVYTFNDLARLPGLLDSLPTQQQSSLPQRVAAHPLFPAKI
>A0A0Q9LGR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Soil522|TrEMBL
MTLILEKGKLAEDHFIVTAELIPPRSWNPQSLIEQAERYRGYVDAVDLSDNLLAIARLSP
VVGAHFVKQVGVEPIVQINLRDRNRMAIQSDLLGLAALSVKNIAILGGYPARVGTEPNAK
EVYDLQTMELVSYVRKFVDEGKLFDGTLLEEKPTFTIGTVENIAGKPIKELIDRLEAKVE
GGTNFVRTQLVFDMDLIGEWMEEARSRGLHERITIMASILPLRNAEHVDTALKIPGIVIP
DSFKARLTAAESKEEGLTIAAELIGKLKDISGIKGIHIRPIGGAEDSVVKVVKLAGLEPV
NTVKVSI
>L8P927|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces viridochromogenes Tue57|TrEMBL
MALGTASIRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGEWVPHPQGLTYAAELVELIKASGDFCVGVAAFPAMHPRSADWENDVRHFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAAGCDTPIIPEIMPIASVKTLERIPSLTNAAF
PAALKERILTAKDDPTAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHPPQA
>A0A2P7SQX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium ephedrae|TrEMBL
MNQFRFSRRPDMGGRIRVSFEFFPPKTDEMEEKLWQTVTRLEPLGPRFVSVTYGAGGSTR
ERTARTVRRILTETRLTPAAHMTCVDATRDQVDQVVAEFAEMGVKRFVALRGDPAEGVGA
RYRPHPEGYANAAELVGAMRAVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDSGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGVLPVHNFSQVANFSSRAGAHVPAWLAERFD
GLQKDPQTHALVASAVAAEQVMDLMERGVEDFHFYTMNRADLVFAICHMIGIRAHEPAVD
AGSAAA
>A0A3D0EF71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MFIRDIFAQKKPVLSFEVFPPKKDSGLDNVISAVDELSKMPIDYMSVTYGAGGSNSKNTA
YIASHLKNNLSIPSLAHLTCVANSKDDIKVKLQEYKDLGIENILALRGDKPKDYDGEIFP
GYHYANELVEAIKDFGDFCVGGACYPECHPDSPSLDADIENLKVKVDAGVDFLVTQMFFD
NDEFYKFRDKLAKKGINKPITAGIMPLTNAGQIQRMAILSGGASMPSKFLRMISKYQDNP
EALKQAGIAYAVDQIIDLLSNDIDGIHLYTMNKPETAQKIVNVINNLFV
>A0A517XKQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia maris|TrEMBL
MRISELYQGGTFGLSVEIFPPRNESGDAELFKTLEELVRYQPAFVSCTYGAGGSTSKRTI
ELCALIQNQLHNTATAHFTCVNSTREELVEWLQNAVDAGITNIMALRGDPPAGQETFVPA
DGGLKYANELVSLIRKHFPDMGIGVAGYPECHPEASDAEVDLTNLKRKVDAGADAIYTQL
FFNNEHFYQFRERCLKAGIDRPIVPGIMPITEYRRIQRIMSMCSSEFPADLVGQLEAAQD
DLESQFEIGVEYAIRQCEQLIKEGVPGIHFYVLNRSQACKRIFDALGFPETQENIAT
>K8Y2C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira santarosai serovar Shermani str. LT 821|TrEMBL
MDEDKSKFSFVFNDQELMKKISEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSRLD
PDFVTVTYGAGGSTRSKTAQILSEISKNYSFPTVSHFTCVGANQEQILKTLKEIRSSGIV
NLMALRGDPPKGEGQFKKTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPNAKNLEED
VENLKRKVDAGADFLVSQLFFVNSIFENFLNLVRTAGIRVPVIPGIMPITSFSQIERFRS
MAGCEFPSSLIEDLQEVEHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYD
IVRELKS
>N8Q852|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter parvus NIPH 1103|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLHIVHQELQRLNPEFFSITYGAGGSTRERTLATIHDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGNHFHIEVAAYPEMHPQADSFDADIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERLEKEGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1H1NYJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium paraoxydans|TrEMBL
MSSTFDTARASRVPFSFELYPPRSESSQEALHETVRRLAAAGPEFLSVTYGAGGSTGGRS
LDVLRFIREHTDVEPLAHFTCVGNTYAGATALIREFLDAGILRFLALRGDPPAGQSEPFL
GDLESAAQLVQLIDRVQAERAPYQESPVPGLPGAALVAPRQKVDIAVAAFPKGHPRATHR
TQDVEALLAKQAAGATFAITQLFFHPDDYLAFVERARAGGVTIPILPGIMPITSPTRLAR
VLELTGEHLPSELSIALDVEPTAEGRREIGISWAARLAADVVAGGAPGVHLYAFNQHETV
LTVLAEAGIVPALRH
>H2N935|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pongo abelii|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKAHPECERDGGSMTLLP
DALRWSHSCPTCLLHSAASLGNPTLLRVSPTPASSPPPDDGS
>A0A534A0A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSLCQKFKVSFEVYPPKTQKGLNDLNQTRDELCRLKPNYFSVTFGAGGSLQQKSLDVVRQ
FVAAGISVTPHISCVNMTQARLESLLREYQQLEIRQLLVIQGDLPTDKSSLDIDFHYASE
LITAIRKITGNYFHIIVAAYPEFHPLAFSPTTDIENFKRKIEAGANSAITQFFFNSDAYF
RFLEACDKSAIRIPIIPGITPIMNYQKLMQFSNACGAEIPLWLHKHLKTYVDDPISLQEV
GIEFVTKLCHSLLQNGIKEFHFYTLNRAEPTQSIIRNLNTSQSQLKNILN
>A0A6L7VXY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGGTDFHLSFEFFPPNTPDGWSKLLRSARRLQNENPDFFSVTYGAGGSTKHRTFQTVKDL
RAEGFNVNPHLSWGDVSREEISLTVQGFLELGIEGMVVLRGDSPSGSVPSVMHNASELVR
LIRHEIASELQIFVAAYPEMHPDAQTPSQDLQFLLEKVQAGANACITQYFYNADAYLNFV
ERCRGFGITVPIIPGVMPIYNYDQLVRFSQNCGAEIPRWIERRMREYRTNKKALEDFGVD
VVTELCERLRDEGAPGFHFYTLNRALIPRQILQSLNLQREPS
>A0A0L0P7K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida auris|TrEMBL
MSTVTSKIRSLAPGERFCSFEFFPPKTDAGFRNLLARLSRMMALNPLFLTVTWGAGGSTA
EKSLDLAATCQKELGVTTVLHLTCTNTNKEIIEDALQRARAAGIKNILALRGDPPRTEEY
WTPNCDFSSAVDLVRYIRQNHGDYFCIGVAGYPEGHVEGADASQQDPRKDLPYLVEKIEA
GADYVVTQLFFDVDKFVAYEKLLRETPQLKNVILIPGLMPITTYRVFVRATRLSHANVPR
DILSKLDAFANDDDTVKTIGLDVLTKMISEIDQRTEGRIRGYHFYTLNLEKAVASIINRL
PVLQNMISHNKLVEHDDAVASDSDEEFAPPMKNGRRKSSVNENQVAVPDDAKRALVSKAL
SKDPKSIVDISTGKGALGKDATWDEFTNGRFGDSNSPAYGEIDGYGPNLKLHTNKEVEET
WGNPESTADITRIFVDYLSNKINVLPWADSELSPETGLIQEELFELNERGWFTLASQPAV
NNCKSSDKILGWGPPNGHIFQKLFVEFFIPKKQWKDELLPRISKQVEEKTITYYCGDASG
HISLNLPIGKGKDSNTKSAVTWGVFPLKEVLQPTIIDYESFKAWNEEAFLLWLEWARCYR
KDSKSYQLLNDIYNNYYLVSLVHHDFTDEFVLWTTLLSD
>A0A7C5BE52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratifractor sp|TrEMBL
KTLQKRMVKKLNYGSRAIITQPVYDVENAKRLLEIFQEAKEISIRETSKEAQLIFGQFPA
VRARTVNFIDDNVPGIKVPKKIIDEMNLAAMDGKEKEEEIGFALSKQIFKEISTLHPKLH
LMTHNRFQLCMKLIEG
>A0A836K6S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania orientalis|TrEMBL
MSGLILDAIAAEDVGKWYTSYEFYPPRSEKAEEEFMKVLIPKFIRQSPVFLDLTWGAGGR
TSETTMRLCKDLQHAYPDTPINMHITCTNMPRGLIKETLDFAKAHGIRNILALRGDPPHG
EEYQANPDGFACAKDLVRYIHATYGDYFCVSVAGYPEGHPSRIAEDGTISDEDSQKELDY
LKEKVDAGASVVITQLFYDASLYVKFVKRCRERGIMVPILAGLLPITTYAGFKRMVSLCK
TSVPSDVRKRVEELKDNPEGLKEYGVEQCVQMIEHIRSSGLDYHHLHFYTLNSSAQTFKI
LKRLDALVE
>A0A7C5KVY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
METQKAYPRVYSFEFFPPKTEEGAERLRRTRDELARLKPRFFSVTFGAGGSTRERTFETV
TEIQRDSGIEAAPHLSCVGSTKENIRDILAAYREAGIRHIVALRGDLPSGMGQPGEFRHA
NELVAFIRAETGDHFHIEVAAYPEFHPQAPDAIADIDNFMRKVEAGADSAITQYFYNADA
YFAFIELCEQRGLRIPVVPGIMPITNHTQLARFSDMCGAEIPRWIRKRLEAFGDDRESIR
AFGADVVTDMCRRLLDAGAPGLHFYTMNQAGPTRMIWERLGLD
>A0A6N8ZWB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MQFEDEPLVPGDPLPIRPGHSSFGRFERVLRAGGFAVTAEIAPPDSANPAEVYERAALFD
GYVDAMNATDGSGANCHMSSVGMCSLLCRRGYAMVMQVSARDRNRIAIQGDVLGAAAMGV
ASFLCLTGDGVDVGDHPQAKPVFDLDCMSMLSMIRRMRDESRFLSGRKLTEPPRVFIGAA
ANPFAPPLDYRPLRLAKKAAAGAQFVQTQYCFDIDAFGRYMAAVRDAGTHEKVFILAGAG
PLASARSAEWIRSNVPGIHIPDAVIRRLKGAQNQQREGVNICIDMIHRIREIEGVRGVHI
MAYRQEHRVAEIVERSGVLDGRRPWQPSVDWNSAAWDQGHAKAPGTPAGQPMDKAS
>A0A359GYP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MELNPKPIFSIELYPPRTTPDESKLDEVHDQLASLEPDFFSVTYGAGGSTKQGTKNIILK
YQQLGSNMVPHLSLGGTDRDDIRILLTAYKAAGINHLVALRGDLPPNTTTPVQHQYASEL
VEFIRLETGNHFHIDVACYPEPHPDSTSYKSDIAYFKKKIDAGANSAITQYFYNADAYFY
FVDYCSKAGISVPIVPGIMPINNYTNLKRFSAKCGAEIPHWLQKRLEGFEGDVEGLKEFG
IEVVTTLCERLLAGGAPGLHFYSMNLAKSVNQIWKNLALSDRS
>A0A534GH60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSDESCAMNAESGRTPIRVSFEFFPPADEAMGAMLWKSIERLAPLAPRFVSVTYGADGST
RERTHNVVTRIQRETPLTGAPHLTCIGASREEILEIARGYWDEGIRHMVALRGDPPQGEG
ARRPNPRGFRYASELVAALAGLAPFDISVAAYPEVHPEASSAAADLENLKRKIDAGATRA
ITQFFFDTDAFLRFRDALAAAGVHAPIVPGILPITRFP
>A0A523JRF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSVTDLKNRLAEQSAQISSVNVSFEFFPPKTPKMESILWDSIENLAPLNPGFVSVTYGAD
GSTRDRTHRVVRRILTETDLVAVPHLTCIDASREEIQEIAKGYFDLGIRHIVALRGDPPA
GCTEYRPRKDGYAYASDLVTGLREVADFEISVAAYPEVHPEAPSQRFDLDNLKRKVDAGA
TRAITQFFFYNDAFLRFRDLCAANGIDVPIVPGILPITRFPRLVQFAKACGAAIPPQISQ
QFEGLENDPDTHQLVAASVAIDQVRRLQQHGVENFHFYTLNRSRLTYAICHILGIRPQQG
IAHASA
>A0A534B7W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPILPGHTSPGRFERVLRSGAFAVTTELAPPDSADPEDVYKRARIFDG
YVDAINATDGSGANCHMSSIAVCALLTRVGYAPIMQISCRDRNRIAIQGDILGGAAMGVC
NMLCLTGDGVQAGDHPQAKPVFDLDAVSLLALGKTLRDEHHFQSGRKITFAPRVFFGAAE
NPFAEPLAWRPQRLAKKVEAGAQFIQTQYCFDLERLELFVRGVEELGLLDKVFILPGVGP
LPSAKTAEWMRRNVPGVHVPDTVIRRLAGAERPKQEGVAIAVELVQQLREMRGVAGVHLM
AFKMEEFVPEIVQRAGVLGPRIPWYPDRDKRLAEKKATA
>A0A534H8B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPIRPGHTSPGRFERVLRAGQFAVTTELDPPDSADPEEVYRRARVFDG
YVDAINATDGSGANCHMSSLAVCALLTRVGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQALPVFDLDALTLLETARTLRDEHHFLSGRKITHAPRVLLGAAE
NPFADPIEWRAQRLAKKVAAGAQFIQTQFCFDVPLLRTFMNRVEDLGLLDKVFILVGVGP
LRSAKSAEWIRTHVPGVHIPDEVVKRLAGASDGALEGRRLCIDVIQEIRAIKGVHGVHVM
AYRQEETVAEIIQRSGVLGGRVPWNPGRDPPANTNRMTSEPTPSAALEPARS
>A0A4R2PGX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. BK235|TrEMBL
MTFSVNQLEEARRALDAPLYADVGGDVDVSFEFSPPKSEKSEETLWQSIETLCPLGPRFL
SVTYGAGGSTRDRTHATVARIARETAVPAAAHLTCVEATREEIDAVAQEYWAAGVRHIVA
LRGDPPAGAADYAPHPGGYENAAALVAGLRRLHPFEISVAAYPECHPSSADLAGDLDNLK
RKLDAGANRAITQFFFEAETFFRYRDAAAAAGITAEIVPGIMPIGSFAGVQRMAAMCRTD
VPGWLVRLFEGLDDLPAARQLVAATVAAELCRKLYAGGVKQLHFYTMNKAELSYAICHLL
GVRAAPRRAVAAA
>A0A661C491|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKSQKKFTKKFSFEFFPARTPEAVVKLETTMGRLAKLNPDYFSVTFGAGGSTREPTFETV
KNISEKTSIEAAPHISCIGVMTDEILEVLETYRSIGIKKLVALRGDLPSGSAGGYGQLRY
ANELVEFIRKETGDHFHIEVAAYPEFHPQANNASEDLSNFKKKVDAG
>A0A3D1XI47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
NAVPHLSVGGSSDAELDQLTDHYQHIGVRQILCLRGDQPSNSGQRPVYAKDLVERLRSRY
QDHFELSVAAYPEIHPDAASADADIQHFVAKVRAGASSAITQYFYNCDAYAFFLDRCAAA
GLTVPVTVGIMPITNIESLQRFSAKVGADIPRWLEKSMSGYAEDEKSLIAFGVDVVTELC
EKLLQMGVPGLHFYTLNRWGATSQICRNLGFREI
>A0A1I3Z7N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. cf310|TrEMBL
MDATPSPAPPMLPISFEFYPPKTDEQRAQLDKTAAKLKVRKPHYVSCTFGAGGSTLSYTP
DTVRHLRDAHSLDAAPHLSCVGGTRAEIRQLLNQYREIGCRRLVTLRGDLPSGMASAGDL
RYANELVEFIRAETGDHFHIEVAAYPEMHPQARDAHSDLENFKRKVRAGANGAITQYFYN
ADAYFRFVDDVRAAGIEVPIVPGIMPIANFSQLRRFSDLCGAEIPRWIQQRMMAYGDDVD
SLREFGADVVAQLCQRLIDGGAPGLHFYTLNLSKPTLSVLSRLS
>A0A3B9X3T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTQGNSASATQNFSFEFFPPRTEIGEGKLDAVHEKLAALKPDFFSVTYGAGGSTREGTRK
SVLRYQNAGSSVAPHLSFGGANEHEVLGLLEDYKSAGVNRIVALRGDLPSGAGSSSNHRY
ASELVSFIREKTGDAFHIEVACYPEIHPESAGYINDVKFFKEKVEAGANSAITQYFYNPD
AYFRFVDFCQAQGIDIPIVPGIMPISNYANLTRFSKGCGAEIPQWLGHRLDSFGDDNESL
KIFGVDVVTELCETLLQGGAPGLHFYSMNLANDVSEIWNNLNLSDRD
>A0A2E9NTA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGTPRLSFEFFPPKTPEAGGSLEQTVNRLKLLSLEFVSVAFGADGSTRRHTYQAIRDILT
KTTPRHFPHLTCVGAPQNEIVAIVADYWSMGVRQIIALRGDPQGPRNPITFLITKAFGRI
SVMGT
>A0A2E9NWC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTFDAKGIPNGWSIEITPKETKTISCFSTFLEEGTKVNVTNLPKTSIQDTLAAVEQLKH
DGMNPIPHITARTITDEDDLTRIVSNYASLEISEVLIIAGSKGQAAGSFSSSVELISSGV
FEHFGIVNIGVAGHPEGSPDITKQQLEDALYQKNHLAVSRDLNIFLETQFCFDAQKIIDW
EKAIRDRGNSLPIRVGIAGPTKLLSLINFAIKAGVGPSLKFLINERDKLTKLVTSYDPTE
LIFSLAPQFSPAANTCFESIHFYAFGGFQETAKFAQKLFK
>A0A661GI39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGSQHTFSFEFFPPKTADGVDALDQARTRLAALEPDFVSVTFGAGSSTREGTLETVPACQ
AAG
>A0A3B8T138|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSAPRVSFEFFPPKTPEAEASLWKTVERLAPLNPEFVSVTYGADGSTRERTHQVIESILT
KTELKPVPHLTCVGAPRDEIDAIADDYWSMGVRQIVALRGDPEGGAEADYQPHPNGYAYA
SDLVEGLLAKHPFELFVAAYPETHPQAISADTDLDNLKRKVDAGGHRAITQFFFDNAIFL
RFRDRVAAANINVELIPGILPVTNFNTLVRFADACGASIPATLKTLFEGLDEDPSTRQLI
AAHAAVSQAEDLGREGVNDFHFYTLNRADLSFAVCHALGVRGNA
>A0A534HRA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSARSVEPPIRVSFEFFPPADAAMAAILWDSIERLAPLGPRFVSVTYGADGSTRERTHEL
VTRIQRDTALTGAPHLTCIGASRGEILAIARGYWSQGIRHLVALRGDPPQGQSSHRPHAA
DFRYAVELVAALAALAPFDISVAAYPEVHPEARSAAEDLANLKRKIDAGATRAITQFFYD
TSVFLRFRDALAAAGVHAPLVPGILPITRFPQVRRFAERCGASIPRWLHERFAGLDDDQD
TCRLLAASVAIEQVEALRRHGVRDFHFYTLNRAALTYAICHALGLRPVARAAGAARQEAL
G
>A0A534CBN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTQQLQHRAPLPEVSLESIIAGLAREASVEINVQDLRDVEASRALLAPGRRIFVSFLPKQ
TWEETAAACRTLKQAGFDPVPHVPVRLLTDEQMLDELVASLVRDVEVEELLLLSGDYPQG
RGPFSRVEDVLETGVLAKYGLQRVSFAGHPEGHPVVPVEEVRRAERAKTLGAAESGLEVS
FVTQFFFEADPFLAWVEAMRSSGVQVRLVAGLAGPARISTLFKFAMRCGAGPSIRALGAR
PTAFTKLIADHGPQNVLRNLAQAQSTGASDFAGIHLFCFGGYLHTCAWLHRVASGEFCLN
RTGGFDIN
>A0A496WAC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTQADETGSKLQQVLEAGQFAMTAETSPPDAASAEVVLSRVRCLKGLADAVNVTDGASAR
VHMSALAAAAIMAREGIDPVLQLTTRDRNRLALQGDVVGASALGICNFLCLTGDKMAAGD
QPDAAEVFEIDSGALMRQMRDMRDLGTYPSGREINPPPALFIGGAEVPSDPGADWSPARI
LAKIDNGAQFFQTQYCFDLGTVERYCHRLVEEGITEKAHFLIGIGPLASAKSARWMTENL
FGVHVPDEIIRRLDGAEDQRAEGRAVCAELLQGFAEIKGCAGAHLMAPHQEAACAQVIEE
SGLLQQRGSFFKEPLTVHPLFLGPKKREDAMS
>A0A480BSA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MVRINRNTIGTEVARSGVTTGESDSPVLSVEFFPPKTEQGVAILAKTRDELAAIAPAYAS
VTFGAGGTTRSGTMETVIAILREDPFPAAPHISCIGATRTQIAELLDRYLDLGVRRVVAL
RGDLPSGSGSAGGDFRYANELVSFIRETTGDRFIIEVGCYPEMHPQALSVAADLENFRRK
VSAGADAAISQYFFNPDAYFRFVDDVTALGVTIPIVPGVMPITNHTQLARFSDACGAEIP
RWIRKRLEGYGDDLEAIRAFGEEVTIRLVGTLLEGGAPGVHFYTMNRSGPTLAVARALGL
GPDH
>A0A673IBE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus rhinocerous|TrEMBL
IGGSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHWFSLEFFPP
RTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLESVLH
LTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLVKHIRCEFD
DYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAETFLRFVKNCRAIG
ITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGIQQAVEMCK
VLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKVEDVRPIFW
ASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEELMN
EGSVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGILTINSQPN
INGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVQGKN
ITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRM
IIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFATDQITVT
>A0A839VH48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas cerina|TrEMBL
MSTQEHPLGISFEFFPPSTEAGHDKLMRTRDALARRQPRFFSVTYGAGGSTQHRTLNSVR
AVRESGITTAPHLSCIGSEKAVLRDLLTGYREEGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGEHFEIAVAAYPESHPQAPSLDRDLENFARKMKAGANFAITQYFFTADAYF
HFVERARALGVEAPIVPGIMPITNYAKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAF
GEEVISRLCQRLLDGGAPGLHFYTLNQAEPTLKVLNNISA
>A0A099RRW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp. HMP52|TrEMBL
MENKFKESLLDKNTLSVTWELVPGRGANEKAQQTAIASAEQAAKGGRVHALTITDNPGGN
PAILADYLGMEIIKLGIEPLVHFTCKDKNRNQMESQLYALDRAKVRNLLVMTGDYTYSGF
KGRPKPVFDLDPSNTLQLITEMNKGLEVPGMKGPTYHAPSDFFAGAAVSPFKSTEAELMI
QYYKMKKKIQGGAQFIVTQLGYDARKCHEVLQFLKVNNLDVPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNTEKTAEDKGVGQRMLRAAKMYAFMKGMGFAGVHIGGHNLKYEQ
VEYIIDKGEELSPNWQDYIKEFDYPQNNGFYYFEKDEKTGLNTDRPTNRANRPLDAPAGA
MNSMMRGMHSLMFTPNKKLFPVLRSMYHAAEGKKKAEKRLHAVEHIAKVVMLDCKDCGDC
AILDIGYLCPMSQCPKNQRNGACGGSLDGWCEVFPKEKKCVWVRAYARLKKYGEEATLDV
PPVPPANWDLYQTSSWSNFYLGKDHSAPVLGIKRPESKIKK
>A0A7W7MTF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes digitatis|TrEMBL
MPPKTREGEQLLWQTIRELETLRPDFVSITYGAGGSTRDTTVAVTERVATETTLLPMAHL
TAVGHSVAELRNVIGRLAGAGIRNVLAVRGDPPGDPMGEWVRHPDGVLYAEDLVRLLRES
GDFSVGVAAFPYKHPRSADVETDTRNFIRKCRAGADFAITQMFFEADEYLRLRDRVAAAG
CDTPIVPGVMPVLRMATITRAAQLSGAPFPRALQARFERIADDADGVRKLGIDLCGEMCQ
RLLDEGVPGIHFITMNRSTATREVWQRLAANVPV
>A0A6M0M6R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKHIKKILALRGDISDEPMKDDFRFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPEKFIRILEKYEHNPIALRDAG
IHLYTMNNANTAHSIHASISSLFTV
>A0A6V8MS93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomonas paludis|TrEMBL
MKKFLDRIAQGVLIGDGAIGTMLYAKGVAPEANFEHLNLVRPELVLELHREYVAAGAQVI
ETNTFGANCAKLSAIGLGGKVAEINRKGAQLARSAADGHDVFVAGSIGPLGRGKSDLAPE
QITECFRVQAAALAEGGVDLLILETFSELDELLVALSAARETGLPVVANLAFGEGGRLPG
GTSAEGAARALAAAGADIVGANCGAGPLELLATVKRIAAACSLPLAAYPNSGFPEYIDGR
YIYRTTPEYFADRAEELVAAGASLVGGCCGTTPEHIRAMAARMQGKVAGAAPSPLTPLPP
ADRSPSVGGGPEGEGELTAAQPLSPRERVPEGRVRALPRSESAAASEALTPSPSPACGPK
PYGGRRPEGRGELQSSFLDRWGAEPVITVELDPPKGLDCAKVLAGSRALKEAGAHAINLA
ENPLARVRMGNLALASLIRREVGIEVIAHVTCRDRNLIGMQSELMGASLLGVTSILAVTG
DPASLGDEAGASSVFDLNSFTLIKLLSDLNSGVNALGNPIGSGTGFTIGAAFNPNTQNME
VQVRRLVKKVANGARFAQTQPIYDLARFEDMMEQTAHLGIPVLPGVLPLVSGRNAEFLHN
EVPGIVIPEEIRKRMAGKSGDEGVAEGLAIAREFIEAASAKAGGFYLIPPFGKYEIAVEL
VKFIKNKAEHRGH
>A0A7X3EAF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNLIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTF
>A0A6N3FM46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter agglomerans|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSASIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A2S9SR05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter cryaerophilus|TrEMBL
MFETLISKLQEDKYLTLETTPQHEPSMHNIVEKIKKFKIDSKVDGFTCTDNPLAKLKYNS
LFAALKLQQEFKKPVIATMTMRDRNKIALQSDLLGANDFDIRAILALTGDPANMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFAVVNAYAKNFGSLEKKMHLKI
QNGAVGVITQPVFDIENVKKLLENFENAKENVEGDKRKAQLIFGVFPITKLRTALFLSAQ
VPGIHVPQFWIDELEKAHNISEEEEYKVGMHLSKNLFKEINKIHPKIHLMTANNKFEVAS
EILA
>A0A5Q8CGH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1A.F.Ca.IN.022.07.1.1|TrEMBL
MSIRHQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVF
LGAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIAGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>C5A8X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia glumae (strain BGR1)|TrEMBL
MKPIELSLEFFPPKTAEGVDKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLLAAPHLSCIGASKDNLRAVLDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRLEVAAYPEYHPQSRSPKLDLLHFAEKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFTQLMRFSEMCGAEVPRWVARRLESFGDDKESIRAFGADV
VTAMCERLIREGAPGLHFYTLNAATATKVVCERLGF
>A0A1L3J599|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gramella salexigens|TrEMBL
MKITEHINSAKNRTLFSFEILPPLKGQNIKSIYENIDPLMEFKPPFIDVTYHREEYVYSE
KENGLLEKKIVRKRPGTVGICAAIQSKYGVDAVPHILCGGFSKEDTENFLIDLDFLGINN
VMALRGDAVKSETYFTPEANGNCFASDLVTQIDDMNKGKYLDEVIEKGHNTNFCTGVAGY
PEKHMEAPSLDRDIERLKQKIEAGAEYVVTQMFFDNQAYFEFVDKCRKNGINVPIIPGLK
PIATKRQLSIIPHRFHVDMPDSLIREVDKCKDNKEVRQVGVEWCIQQSRELVSAGVPVLH
YYSMGRSTNIQKIAAAVF
>A0A1F3JMJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWF2_40_13|TrEMBL
MKVIDLINNRKKTLFSIEIVPPLRGNKVEGIYQRIEQLIEFQPAFINITYHKDEATYSQL
KNGKIIKRTISKRPGTVALTASIMNKYKVEVVPHLTCGGFSRDQAENALIDFNFLGIENL
LVLQGDAGRGQDVFIPDPDGHRYAVELVEQVMNMNKGKYLDENLEQANPSNFCVGVAGYP
EKHYAAASLESDIQYLKAKVLAGAEYIITQMFFDNKHYFDFVQKCRAAGITVPIIPGLKP
IALLDQVEVLPRLFHLEIPEDLKKEIKKCKDNKEALEVGTHWSIEQAKELINQGAPVLHF
YTLGAGSSIRKIAEEIF
>A0A5E4TM64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea eparura|TrEMBL
MSGSHDNRTIMTQPSFSFEFFPPKTAEGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQKG
TLDTVVEIQREGVEAAPHLSCVGSTRDNIREILQTYRQHGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGEWFHIEVAAYPEYHPQAKSPRLDLEHFAHKVKAGANAAITQYFF
NADAYFRFVDDAARLGVDVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
DSIRAFGLDVVTALCERLLAQGVPGLHFYTLNAASATKAMWQRLGL
>A0A5S4GUU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura geliboluensis|TrEMBL
MRRVRPDRPPTVRELLAAGGRSFSFEFFPPKTDKGARNLWRTIRELESLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVDHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPDGVEYAADLVRMIRSYGDFCVGVAAFPYKHPRSPDVGSDVRYFVEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDVPILPGIMPVTQLSTIERSEQLSGAPFPPEV
KARFDAVADDPEAVRRLGVEHAAELCRELLEQDAPGIHFITFNKSTATREVYSLLGAEEY
GARGSVPPMTA
>A0A284RSS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armillaria ostoyae|TrEMBL
MDSPGMPAFIFASIGKRMRALDPEFINITWNTGGRTSDLTIGIVESKPVYILPVPTCPKR
KLISPYEYISITFDYVLLRFPQQQLLPPEEHDQELKYLKKKVDTGVSFIFIQMFYDVQVF
VAWVNAVPKGQETIKPLLWKHAMSHTQLSQRNDPQSFW
>A0A7Y5AYC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus firmus|TrEMBL
MSFLNKLKNEIIIADGAMGTLLYSYGTDSCFEELNLLQSEQIQHIHEAYIGAGAELIQTN
TYAANYLKLQRYGLEDSVKEINSAAARIAKKAAAERAYVAGTIGGIRGFKPNMITLEEIK
RSFREQLYCLLLENVDGILLETYYDLEELETVLAIARKETDLPIIAQVSLQEAGVLQNQT
SIADALAKLEGIGADVVGINCRLGPHHMLKTLESVPLPKHAHLSAYPNASIPAYTDGKFH
YEGDAEYFRQSAIEFRNQGVRLLGGCCGTTPDHIKAFADVLKGLPPIEEKEIKAVNKVIV
SEKPESSRELPPLQDIVRERPSVIVELDPPRKLDTSRFFEGAKALKEAGIDSITLADNSL
ASPRVCNSALGYLVKQQTGLRPLVHVTCRDRNIIGLQSHLMGLHALGLNDILAVTGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSFSGKDLGQKAAFSVAGAFNPNVRSLEKAVG
RLEKKIEHGADYFISQPVFSEEKLLEVHEAVKDLKAPVYIGLMPLTGSRNAEFLHNEVPG
IKISDSIRSRMASLKDDPAQAGTEGIAIAKSLIDAAAELFNGIYLITPFMRYEMTVELSN
YARETTERLSRRKQHA
>G4D0F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium avidum ATCC 25577|TrEMBL
MQTQKPTIADLLAAGDRPLHSFEFMPPRSEDDVYRLWSATDALVPMAPDFISVTYGANGS
RRDRTLRCTQHMVSTGLRTVGHLTCVVQSVSDLEQMVADYAESGVNHILAVRGDMPGGAG
QPWVAHPEGLPNATELVRLVKRVHPEACVGVGAFPDGHPESADIDLDARILVDKAEAGAS
FAITQLFFLPSHYQRLVDRVRAMGCDIPIIPGIMPIASYGQIRRFAELSGTDVPAELVAR
IEAVKEDKAAVRRIGLEAAVDMCCELLDSGAPGLHYYTLNRSRATTELRTMLARRRPQLA
DLPADFEATPAA
>A0A011NWG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Accumulibacter sp. (strain BA-93)|TrEMBL
MTQHKRTFSLELFPPQTPEGAEKLRAARARMAALKPRFFSVTFGAGGSTRDRTLETVLDI
QGEGHQAAPHLSCIGSTRESIRSILEQYRANGIRHLVALRGDLPSGMARPGTFRYANELV
EFIRAETGDWFHIEVAAYPEYHPQAKSPRDDLVNFKRKLDAGANSAITQYFYNFDAYAHF
IDDCQAIGIDVPIVPGIMPIASYSSLARFSDTCGAEIPRWIRKKLESYGDDSASIRAFGL
DVVSGLCQQLLANDAPGLHFYTLNQDALTTQLWQRLHLS
>A0A1H2VMW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter enzymogenes|TrEMBL
MLPISFEFYPPKTDEQRSQLDKTAAKLRAFAPSYVSCTFGAGGSTLSYTPETIRRLRQKH
ALDAAPHLSCVGGTRSEIRELLALYREIGCRRLVTLRGDLPSGMASAGDLRYANELVEFI
RAETGDHFHIEVAAYPETHPQARDALSDLENFKRKVRAGADGAITQYFYNPDAYFRFVDD
VRAAGIDIPIVPGIMPIANFSQLRRFSELCGAEIPRWIAQRMQAYGDDADSIREFGAEVV
AQLCSRLIEGGAPGLHFYTLNLAKPTLSVLARIA
>A0A482UBM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas songnenensis|TrEMBL
MSTSQRPSISFEFFPTKTDTGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDTKAELRELLNLYKDAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEVAAYPEMHPQARNFEDDLANFVRKARAGANSAITQYFFNADCY
FYFVERVRKLGVDTPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A2G5EVS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquilegia coerulea|TrEMBL
MKVIEKIREAEAENRVVFSFEFFPPKTDDGVDNLFDRMDRMVQHNPSFCDITWGAGGTTA
DLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQDK
FVQIEGGFACALDLVKHMRGKYGDYFGITVAGYPEAHPEVIDSSGVATLEAYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPIGNYKGFMRMIGFCKTR
ECEQNLGLIDEAKISRPLPWRRPTNIYRVKEDVRPIFWANRPKSYLTRTIGWDQYPHGRW
SDSGNPSYGALTDYQFMRPRSRDKKLQEEWAVPLKSVEDIHERFAQFCLGKLKSSPWSEL
DGLQPETKIINEQLENINLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFC
SQDQLTALLGKCKDFPSLTYLAVDKKGNSMSNVAPTDVNAVTWGVFPAKEIIQPTIVDPA
SFKVWKDEAFEIWTKVWAHMYPEDDSSKSLLEKIQSSYFLVSLVDNDYINGDLFAAFKEL
>A0A1B3DZY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. TCU-HL1|TrEMBL
MSQERRYSFEFFPAKTEAGHEKLMATARSLASYKPDFFSCTYGAGGSTRDRTLQTVLQLD
GEVMIPTAPHLSCVGDSKAELRALLAHYKDAGIRRIVALRGDLPSGMGIASGELRFANEL
VEFIRSETGDHFHIEVAAYPEVHPQARSYESDLANFVRKVNAGASSAITQYFFNADSYFY
FVERVRKLGVDVPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVQSIQAFG
EQVITEMCESLLQGGAPGLHFYTLNQAEPSLAIWKNLNLPR
>A4N005|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae 22.1-21|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A015NPY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus darwinianus|TrEMBL
MHISIELIPRDLDGFREELQTIKTRHTPIDTVNVPDLMRLSVRSWEGTAAAKSFYERAIP
HIRAIDFDLREPFKLGSELVDKQLTEILVVAGDPPTDMMRKVYPTKTAELIRKVKQEYPQ
LKVYAAIDPYRSSIREEIGYVGEKLEAGADGFFTQPFLDVRLMEVYAELLPGCEIYWGVS
PVMTDASRGYWETKNNAVFPGNFKPTLDWNVDFARRAIDCAGTVGGHIYLMPIKVDLEAY
LSGIFN
>K7B4H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pan troglodytes|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYE
EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELVNRPTQNARETEAP
>A0A353WV05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagales bacterium|TrEMBL
MNFTRVKISDLLAKNEITYSFEFFPPKNYSSILELGINVGQLMKLSPSFISVTYGAGGST
QDASFDLIDYIQNKIGLTTMAHYTCVNASKEKVEQDLKFLHDRNISNLMLLRGDPPKGTK
DFVNKAGYFQHASDLIELAAAKSLFCIGAAGYPEKHPESVNMDNDINYLKYKVDKGAHFV
VTQMFFDNNYYYNFVQKAREAGIDKPIIPGIIPIVNYKQIKKFSDMCGTQIPDELVQQLE
PYQDNREKTYQIGVDYAIHQCRELLEEGVPGLHFYTLNKSRATVDIFSEIRK
>A0A6C7E735|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ilumatobacter coccineus (strain NBRC 103263 / KCTC 29153 / YM16-304)|TrEMBL
MARIGDLLAAKRTLSFEFFPPKTNQARLTLGKTVGDLEALEPDFVSITYGAGGSDRHRTG
DVVGWMRDETTLEPMAHLTCQGHTRTEVASLLVDYRKRGVANILALGGDAPADGTAGKSD
YTYALDLLHDVAASQSFSIGVAAHPEVHPRSESRAADRRHLADKMRLADFAITQFFFEVE
HYERLVDEMAALGIDKPIVPGIMPITNKAQISRMAEMSGAALPTWLVDRLGYVDDPVHVR
RLGIELASKLCNDLIAAGAPGLHIYTLNRSATAKEIVANLELATV
>A0A2A2YC38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiae bacterium AMD-G2|TrEMBL
MHIRDILRHSKPSFSFEFFPARTEASAEDLYQTISELEPLAPSFVSITYGAGGGTRELTH
QLVARIKETTGIPPIPHLTCVGHTKAEVEQLLLRYAALGVCNILALRGDPPKNQNDYDWS
HGDFRYASDLVRFIREFNESGRHPLGGFGIGVAGFPEGHPTTPNRLAEMEHLKAKCAEGA
DYICTQLFFDNHDFFDFRDRCVLEGINIPIIAGIMPVTSLSSMKRMAELAAGSRYPAKLL
RVLSRAQDPQAVENVGIHYAAQQCNELLDGGVDGLHFYTLNKSSATRQIYQSLGMVTSA
>A0A1Y4DA70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp. An276|TrEMBL
MRIIELLKNNKRPFVSLEFFPPANDEAMKDFYHAVDRLQEINPLFASVTYGAGGGKQDKT
LAIVRQLASMNLCVMSHLTCVNAKVQGLAKYLDQLQNAGVCNILALRGDPPKDTPWSWTG
PFQHAADLVRYVRLQAPQMGIGVAGYPCPHPESSTYSDDRGYTLRKIECGADFVLTQLFF
DVREYFELVDWLRQHGCNCPVIPGVMPIQSFASLKRVLSLCGASIPGRLFLELEEADRNS
NGDVARICMDFTVDLISRLLIGGAPGIHLYTLNKADLCLDIVRECGLGKK
>A0A100HJK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus grandis|TrEMBL
MTRVSVELVPRSRSGLRAEIAEVAGALGGVDTVNVPDLTRYSLRSWVGCGFARPGFAAIP
HLRAVDFNPREPLPFLPLLEEHGIREVLVVTGDAPIDMSAKVYDQDAVDLIRRLTRDAPH
LRVYAGLDPYRQSFVRERDYLERKLDAGAAGFFTQPFFDLRLLDTWADLLPDGTDVWWGA
TSILTEASFNYWRARNHAVFPRTFTPTLDCNRVFARDLLTFARQRQHHAYFMPVKVNVLE
YLGGIL
>I8WX40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides nordii CL02T12C05|TrEMBL
MKVIDLIHSNEKTAFSFEILPPLKGTGIEKLCRDIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNKLRRRPGTVAVAAAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYYHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDSDIYWLKKKVEAGAEYAVTQLFYDNQKYFDFVEKARQEGINIPIIPGIKP
FKKASQLSMIPKTFKVDLPDDLVKEALKCKNEAEVQQVGVEWCVKQCRELMAHGVSSIHF
YSIGAVDSIKEVAKEIY
>A0A421CR96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrotoga sp. HKA.pet.4.5|TrEMBL
MKIVDLIKQSNKPVLSFEIIPPNVGESIDSIFNVVDNLIEFYPKFINVTKHANEIEYVEE
NGKIMKIIQKKRPGTVGVSASIKHRYNIEVVPHLICTGFNKYQLEDILIDLNYLRIENIF
VVRGDKKRYTWKETDEYEHASQLVEQIANMNRGIYTFPTKEHNSTNFCVGVAGYPEKHFE
SPNFEKDLDYLKLKVDMGATFIITQMFFDIEYYKNFVNKVRDLGIEVPIIAGIKPLGSKK
TLYNIPKTFHVNIPKSIVEEFEDAKSSQDEYIIGVRHAIKLIEQLLELGVPGVHLFTMGK
GKIVKDVLSAFKGIF
>A0A2G5EVI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquilegia coerulea|TrEMBL
MKVIEKIREAEAENRVVFSFEFFPPKTDDGVDNLFDRMDRMVQHNPSFCDITWGAGGTTA
DLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQDK
FVQIEGGFACALDLVKHMRGKYGDYFGITVAGYPEAHPEVIDSSGVATLEAYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPIGNYKGFMRMIGFCKTR
IPAELTAALEPIKDNEEAVKKFGIDFGTEMCKKILAHGIKQLHLYTLNMDKSALAILQNL
GLIDEAKISRPLPWRRPTNIYRVKEDVRPIFWANRPKSYLTRTIGWDQYPHGRWSDSGNP
SYGALTDYQFMRPRSRDKKLQEEWAVPLKSVEDIHERFAQFCLGKLKSSPWSELDGLQPE
TKIINEQLENINLKGFLTINSQPAVNGEKSDSPSVGPVNCIAWEMQGFSISYVLSC
>A0A7C5Q9H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquifex aeolicus|TrEMBL
MKIGDLLKRGIFSVSFEFFPPKTEEGEKQLFETIEELKTLKPTFVSVTYGAGGSTRDRTR
NVVRKIHEQTGLNVMAHLTCIAHSRKELVEILEDYRRMGIENILALRGDVPRDRPDFRPP
EGACTYARELVELIRERFGSYFSIGVASYPEGHPESPNLEWEIRFFKEKVEAGADFSITQ
MFFENRYYYDFVERCQRAGLKVPIIPGIMPITNFKQIRKFAAMCGATVPQHLIEKMEPVE
DKPEEVTKIGVEFAVRQCEDLLRNGVPGLHFYTLNRSRATLQIYSALKDHVPPSGTHLR
>C7RCN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kangiella koreensis (strain DSM 16069 / KCTC 12182 / SW-125)|TrEMBL
MSRAERQYFHAKELERINHDFASLSGNVNLSFEFFPPNSNEMNSILWNSIKKLEPLQPDF
VSVTYGAGASTRERTHGVIEKILTETSLNAVPHLTCIDATESEIETIAHRYWELGVRHIV
ALRGDKPDERSHTGDFNYATDLIYKLKSLYDFDISVAAYPEVHPEALNAQADLDNLKRKV
DAGANRAITQFFFNSESFLRFRDKCAQNSIDVDLVPGILPVTNFIQLLKFARFTQVEIPG
WMQKLYQGLDQDLITRQLIASHIAIEQVKLLSKEGIKNFHFYTLNRADLTYAICHSLGRR
ECFAAAS
>A0A326UE35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosporothrix hazakensis|TrEMBL
MRTQHPFLERLQRGPILCDGGMGTQIYARGISFERCFDQLNLTDPELIKAIHLDYVAAGA
EIIETNTFGANRYRLQEHGLEHKVHDINRAGAKLAREVRDMSEQPIFLAGNIGPLGVRLT
PLGTVKQQEARDAFREQAEALLESGVDLLILETISDLGEMREALQAIRPITDVPIAALMT
FGEDNTVTSGEDPHTVARVMSELGADLVGVNCALGPAGTLSVIERMQDEQHAFHLAAQPN
AGLPRRVGNRFIYISSPDYFAEYTRHFLQAGVQLVGGCCGTTPQHIAAMSKVLREFAPEL
QQRPKPVKEQAKIELVYDKRVQQQPPRGTKAPSTRLAQLLAAGRFAVSAEMRPPRSIKFT
RFLQNAEYLRDAGVDVINIPDNAMARVRMSNVAAARLIQQFVGTETIIHFTPRDRNLMAM
QSDLIGAHATGIRNVLAVTGDPPTHGDFPGATGIWDVDSIGLITILNNLNRAIDGTGRKL
ASAASFFIGCAATPSATDLDLEIERLQRKVEAGANFIMTQPVYDPETLLHFFDLYKQRYG
ALQIPILVGLQPLHSYQQAEKFHNEVPGIVIPDTVRKRLKEAGERGIEAGLEIIKELLSA
IYPHIHGVYIMPLDRYDLVRELLPYIRSLTEPTSDSQHS
>A0A6V8QQT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma asperellum|TrEMBL
MHIKSLVADTEKTKAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLDKVNDALQKAYKAGCTNILALRGDPPRDQTT
WTAADGNFRYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGAGF
IVTQMFYDAENFLRWVGKVRERGITVPILPGIMPIATYASFLRRAKHMQCRVPPEWMTLL
EPVKNDDVAVREIGKTLVAELCRKLLAGGIHHLHFYTMNLAQATRMVLDELDWTPSAERP
LKQALPWKQSKGFGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTCVQDIADTFVQYLEKKIETLPWSESALAAEADPIKDDLVA
LNKRGILTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLIPPYLLDEMISRLDDFP
NLTYYAVTKNGELKSNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFDANTPSRALIEGIMNEWYLVNIVNNDFRENNTIFGFLEGLQVKDASVPVNSTA
>A0A1V0R5J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Sge12|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSVAELRNVIGQFADAGIRNMLVVRG
DPPGDPMGEWVAHPEGVHYAADLVRLVKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CHAGADYAITQMFFDPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSNAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A2T3JLF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium frigidiphilum|TrEMBL
MGYSHASHLDSLNQNIADINGDINVSFEFFPPSSEKMEETLWHSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLIAAPHLTCIDASRDELRTIARDYWRNGIRDIVALRGD
LPAQGAKPDMYAADLVELLRKEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAAIDVEIVPGILPVSNMTQAKRFAVANNVKIPGWLEKQYQ
GLDDDLLSRQMLGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAEVEAK
>A0A2P9IMP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura parvosata subsp. kistnae|TrEMBL
MALGRSSIRPDRVPTVREMLASGGRSFSFEFFPPKTDEGARQLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERIAHDTTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVR
GDPPGDPMGEWVQHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSVESDVEYFVR
KCRAGADYAITQMFFQADDYLRLRDRVAAKGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPDVAARFEAVKDDPAAVRQLGIEHGAELCQRLLDEGAPGIHFITFNRSSASREVFQRLE
RVPAAT
>C6SNH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis alpha275|TrEMBL
METMLWDSIHRLQTLHPKFVSVTYGANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASP
DELRQIAKDYWDSGIRRIVALRGDEPAGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVH
PEAKSAQADLINLKRKIDAGANHVITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTN
FKQLGKMAQVTNVKIPSWLSQMYEGLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYT
LNRSELTYAICHILGVRP
>A0A387BU29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gryllotalpicola protaetiae|TrEMBL
MRQVPFSFELHPARSDRVAQQLPDRIARLVAAGPEFVSVTYGAGGSSQDASLDVLKHVID
RHPEVRTMAHLTCVGSSVQSSHDTVRTFMDAGVHSFLAVRGDLPLGSTAEEFPGDIRSGA
ELVQLIQAVQHERAPWREVRLPGTPGITLDREGRERVVIAVAAFVNGHPSSRSFQQDIDT
LLAKQAAGANLALTQLFFHADDYFRLVERARAAGVEFPIIPGILPVVSTSGVVRARELAG
EQAPTQLVGRLGAEPTAEGQREIGIDFAAELVQQLVDGGAPGIHLYTRNLHETPLAVLAR
AGLIEAGLYERLVSTEFAGAPLA
>A0A1L6QZ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salegentibacter sp. T436|TrEMBL
MKVTEHINRAKGETLFSFEIVPPQKGRSIQDLYNNIDPLMEFNPPFIDVTTSREEHVYIK
KDDGLLERKITRMRPGTVGICAAIKQKYNVDTIPHVLCGGFTREETEYLLVDCHYLGIEN
VMALRGDAMKHQRYFEPTHGGNCFASELVTQIKDLGEGKYLNEVIESNNNADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKINAGADYVVTQMFFNNKAYFDFVEQAREAGITVPIIPGIK
PIAVKRHLQLLPQVFSIDIPEDLIKNVEACKDNKEVREVGIEWAIAQSKELKASGVPVLH
YYSMGKSTNIQKIAKAVF
>A0A6N7I2X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MLRNIDKIGFSVSDSERPVNRSDAVRWLLDHPRYEVVPLPGVREHVLDHLETGSTVPVTS
APARGVEPTIAVAETLAADGYNAVPHLAARSVRGEVHCKEILDRLAEAGVREVFVVGGDN
PEPAGPYESGEQLLTTIHRLGHSFADIGVPAYPEGHPLLDDETLWRSLQAKQHDATYLVT
QMCFDAKAIGRWVAEARTRGVSLPVLVGIPGVVRRRKLARMSVKIGVGQSARFLRKQSSA
IWRLLRPGGYQPTSLVRDLARLPVVGADIRSLHLYTFNQVENTATWVRTLAGQR
>T0IAI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. UNSWDHB|TrEMBL
MKISELFKTGKPTLSFEYFPARTEKNAETLEKTLGVLASLDPSFVSVTFGAGGSTREGSY
ELVKKLKQEKKLEVVAYLAAYGLRLDEVAAVLDAYRDLGIENILALRGDLGKDGAKEIPA
DTIHYAYELVTFAKKNYNFCIGVAGYPEGHLEAPSLEKDIEYLRYKVDQGADFVIANFFH
DNIYFYHLLERCQKSGITVPVIPGLMPVYSVKMMEMLAANCGAIIPEQLKKGIASLPEGD
ADALVEFGIQYAAAQCEELLREGACGLHFYTMDRSESTAGIVKILREKGLL
>A0A1Q8S767|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum chlorophyti|TrEMBL
MHIKSMLEESRRTGEPSFSFEYFPPKTAQGVQNLYERMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREKEK
WEATDDGFQYAKDLVRHIRATYHDHFDIGVAGYPEGCDDNKDEELLLDHLKEKVDEGATF
IVTQMFYDADNFVRWVGKVRERGITVPIIPGIMPIATYASFLRRAKHMNCKVPEDWMAAL
EPIKNDDVAVREVGKGLVADMCRKIVAAGIHHLHFYTMNLAQATRMVLEELNWLPTHDRP
LKHALPWKQSLAHGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSIKDIANIFVRYLETEIDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSSHPVHGWGPANGYVYQKAYLELLVSPDIYREIVRRIEKNP
DMTYYATTKNGTLEYNASSDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGVDW
AHCFEAGTPSRILIDRIMNEWYLVNIVNNDFHQKTALFDLLDGLSVNEYTDIPSEPQTNG
ASNGASVPA
>A0A177AHI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus destructans|TrEMBL
MHIKDMLNQGEQAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHA
QLTCEMVSVAQSVYGLETCMHLTCTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEK
WVATDEGFQYARDLVKYIRKTYGNHFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATF
IVTQMFYDVRNFLDWVRKVRAKGITIPIIPGIMPISTYASFLRRCNHMNAKIPPGWIEVM
EPVKNDDAAVREIGRGLVTDMCRSILESGINHLHFYTMNLAQATRSVLEQLEMLPSEERP
LKQALPWRQSLGLGRRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGEPKSVKDIANVFLRYLNADIESLPWSEAPISNEADVIKNQLVE
LNEHGLLTINSQPAVDGVKSSHPVYGWGPLNGYVYQKAYLELLVAPELIDELLDRIARDP
GVTYYAVTKSGTLRTNAPSDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHDASSPSRNVIQRVMETFYLVNIVHNDFHQRDALFSLFEGLTVPNIDKAAEGTAAPG
AAPAPAATGVPATNGDKVEDAPPTIVSNVLPVA
>Q938W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces fradiae|TrEMBL
MRTTLREILGSGRLSFSHEFFPPRTEAGTRTLWNAIRRIEPLAPTFVSVTYGAGGSSRDR
TVEVTKRIATDTTLRPVAHLTAVGHSVAELRRIIGQYADAGVRDVLALRGDPPGDPNAPW
VPHPEGLTHAHELVSLVRGSGGFGVGVAAFPERHPRSPDWDSEIRHFVRKCRAGADYAIT
QMFFRVEDYLRLRDRVAAAGCCTPVIPGIMPATDVRQIARFAELSHATFPEGLARRLEAA
RGNPAEGHRIGVEYATAMAGRLLAEGAPGLHYITLNRSTATLEIHRNILGTPAPGSARQV
LAAPL
>N9AEC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter schindleri CIP 107287|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLADFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADNFDADIKRFCEKARAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDAASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A5B0MU27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia graminis f. sp. tritici|TrEMBL
MKISQKLAAAESENRISWSFEYFPPKTDNGLTNLYDRICRMSQLGPIFIDITWGAGGSTS
NLTTEFVKTAHEQFGLETCMHLTCTNMPKSKIDTALKEAYEFGCENILALRGDPPKGSTE
WTATEGGFEHAIDLVRHIRAEYGDHFDIAVAGFPEGHMHSTLSREQQTIYLKEKIEAGAN
FIFTQMFYDVDIFIDWVREIRAAGITVPVIPGLMPIQSWAQFKRVTNFSKTIVPQYFLDK
LEPIQSDDQAVREAGTKLVADMCRKILNSDLGIRILHFYTMNLERGTKMILDELNLNPSR
DITNPLPWKMSLLGKRRSESIRPIFWANRAKSYLSRTETWDEFPNGRWGDSRSPAYGELD
GYGININAATMETLKGLKKFPTSLADLARIFANYCGARFPGEEPVKYLPWSDIPLSEETN
KIEDVLVKINKRGFLTINSQPAVDGAKSSDPVHGWGPRGGYVYQKAYLEFFCCPEKFQSL
TERLEKDPDVTYYAVTKTGDLVTNNTRPGPNAVTWGVFPGKEIVQPTIVELVSFIAWKDE
AFELGHQWAELYKEIAPESARFIHQIMDSWYLVNIVNNDFRKSNDDSEHSALFQFFGPEP
VIVDQDDLPPTTNGLSHPNGLPKTNGSSTPAISEVNGELKNLAI
>A0A1M2V4N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trametes pubescens|TrEMBL
MKFVDKIVQHGRRKLFYTFEFFPPKTDQGFENLVSRIARMVGLSPLALSVTWGAGGTTKE
RSLDLAGLTQVEYGVDTILHLTCTNMEQGTVDAALREAKERGIENILALRGDPPRGEEHW
IPTDSRFQHGVDLVRYIKSTPEFSHFCVGVAAYPDGHPDRDTNEDVELDQLKDKVDAGAE
FIITQLFYDVDNFLQWVDKVRAKGITVPIIPGVMPIQTYASFLRMTKLCATRVPATLMSD
LVPIRHDDQKVKDFGVKLAVDMIRQLQRGGIEGVHFCTLNLEKSVTRVLESLGLAGNIPT
LANRLISDMPSPPERTVTPHTAADRATKELASAPQPELEAGKGELNSAADWDDFPNGRFG
DFKSPAYGDTDRWGSSALQNNAALSHWGNPQTVEDLTNMFMRYLHSKITATPFSPTPLSP
ESLMIFPHLEKLTRRGWWTVGSQPAINGVPSTDDVVGWGPKGGYVYQKCFVEFFAEQKDV
ERIVKRVQEEGAGWVDLFAGNVKGEVLTSVPEGGRNAVTWGVFPGQEIAQTTIIEKESFL
SWKDEAFSIWSEWASFFRPGSQERTLLEGVRDHRWLVSLVHHDYMDPAALWTFLFKGDDP
LV
>D3BTZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polysphondylium pallidum (strain ATCC 26659 / Pp 5 / PN500)|TrEMBL
MYKEKKRMKIIDKINEYKSKNQRFYSFEYFPPKTMEGVQNLYDRLGRMLLLEPLFVDITW
GAGGSTSQLTLEIAETSQNICGLETMMHLTCTNMKVEEIDFALEKAKASGVRNILALRGD
PPRGEEWKKIEGGFGYASDLVRYIRQKHGDHFGIAVAGYPEGHSDCTSKEDDLQHLKNKI
DAGADLIITQLFYDVDMFNDFVGKCRAIGINCPIIPGIMPIHTYAGFKRMTTLSQTAVPP
HILEALEPIKDNDEEVKKYGVKLCVQMCERLVEAGVDGLHFYTLNLERSVRKVLKGLNMV
RPDQLARYLPWAQCASTNRLKEEVRPIFWQHRPRSYISRTGSWDEFPNGRWGDYRSPAFG
DLSDYHLSSLQFNSAQAEQNKDDFGAAPLSTQDVYDRFADYCAGRLKKLPWNDLPLSSES
DEIKEPLVFLNSNGFLTINSQPAVNGASSTDKNYGWGGKHGFVYQKAYVEFFTSPENTAK
LIEYFKKCPSITYHAVNVRGDSLTNTKGTNAVTWGIFPGKEIIQPTVVDHASFVVWKDEA
FALWQSRWASTYPEGSESRRVLESMINSYYLVNVVDNNFVNGSIFQPFKDLMNNLTSPVI
QSTSPTSN
>A0A431NP18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MITPTALSPELPGRLADALRSGRFAVTAEIAPPRGADLVPVRRAAEHLRGWVDAVNVTDN
AGANVRMSSLAGSLALLEEGVDPVMQMTCRDRNRIALQSDLLSASALGVPNLVLMTGDRP
EQGDHPDAAAVFDLDSGGLMSAARTLRDDATLMSGRAVDPAPRYLLGAVDSPGPSADRFA
QKVDGGAQFVQTQFVFDIAAFGGWLGQVRDRGLDTRCGVLAGVGPIRSLRALEFMSSIPG
VVIPEALERRLRGVPSDKVAAEGVAACVETLRELRELPGVAGVHVMVVGDERGVPEILEA
AGLSRTS
>A0A2N7Q260|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenobaculum sp|TrEMBL
MKIIELLKNKKGVSFEFFPPKSQKDKEALLETARELKVFEPNFVSVTHGASGNSTSQKPP
IEYTKETVLELKNSLGLNIMAHLTCISHTKEELINILGFYKENNIDNILALRGDIPKNGE
KRGCSHASELIELITKYFDNEFCIGVAAYPEGHPESPNMEWEIKYFKQKVEKGASFAITQ
MFFDNSYYYEFLDLCRKANIDIPIIPGIMPITNIKQISKFASMCGATIPSYITDALENLS
EEDVVKKGVEIAINQCEDLIKNGVKHIHFYTLNKSKATLDILKAINL
>A0A1W0ZGR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia multivorans|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLDAAPHLSCIGSSRDSLRAILDQYRSCGIRHIVALRGDLPSGMGSVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATKAICERLDV
>A0A7K1Y8X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. HMF7647|TrEMBL
MKITEHISNAKGKTLFSFELLPPIKGQSIQGIYDAIDPLMEFNPPFIDVTSLREDYIYKE
KENGLLEKVAYRKRPGTIAICAAIINKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARRADSAFIPTPGGHCYATDLLQHVKNHNNGKFLHEDVEVAYKSDFCIGVAAY
PEKHFESPNLKTDFRYLKQKVDMGADFIVTQMFFDNTKYKEFVNLCRENGINVPIIPGLK
PITSSKQLVSLPKVFHIDIPEDLSEAVLACKSEKDVKEVGIEWMINQCKELVDFAAPVLH
FYTMGNPEPTKRIARAVF
>A0A2C1Z0T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS037270|TrEMBL
MTFLDKLKNQILIGDGAMGTLLYSFGVDTCSEELNLSQAEQIQNIHRAYIDAGADVIQTH
TYAANYLKLQRYGLEDSVKEINSAAVRNAKKAAQSNAYVLGTIGGNRGIKTSSITIEELK
RSFREQLYCQLLEGVDGLLFETFYDLEELETVLTIARKETKLPIIAQVSLQDPGFLQDRT
PVNEALKRLEGLGADVVGLNCRLGPHHMLLALEQVEIPKHAFLSAYPNASLPTYTDGKFH
YEGDADYFQKSAQRFRNEGVRLLGGCCGTTPDHIRAYASELKNSIPVTEKVVKLKQKPII
VETAPKREYTPLQEIVKERPSVIVELDPPRKLDTTKFFEGAKALKEAGIDSITLADNSLA
TVRISNESLGYLLKSELGMRPLIHLACRDRNIIGLQSHLMGLHTLGMNDILAITGDPARV
GDFPGASSVYDVSSFELIQMIKQMNEGLSYSGKDLGQKTAFSVAGAFNPNVRSVEKAVKR
LEKKIQFGADYFISQPVFSEEKLIEVYENTKHLDTPIYIGLMPLTGSKNAEFLHNEVPGI
KIADSIRERMALLNDNPLQAAREGIAITKSLIDTALDLFNGIYLITPFLRFELTAELAAY
ANQRASEIRGVSYAENTIF
>A0A7D5VA56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinibacter fontanus|TrEMBL
MKSALRPISFEFFPPKTPEGAAKLAAARQQLAQFKPEFFSVTFGAGGTTQEGTLRAVLAI
REAGFAAAPHLSCIGATRDSIRAIVQQYKDHGIRHIVALRGDIPSGMVDLGEFRHANELV
SFLRSEFGDWFHIEVAAYPEFHPQSVSAEADLAHFVRKVRAGADSAITQYFFNADAYFRF
VDEAQARGVQIPIVPGIMPIQNYSQLQRFSDMCGAEIPRWLRLRLQGFGDDSASIRAFGL
DVVTELADRLLDAGAPGLHFYTLNSAAAVSTICQRLGY
>A0A078ABA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stylonychia lemnae|TrEMBL
MKINDKINQALSEDPTNKKTFYSFEYFPPRTEQGIENLLDRIERMGSTNPLWVDVTWNAG
GSTSDITIDLCAHIQNFSGLDVLMHITCTYMTREKIVTSLDRAKELGIRNLLALRGDPPR
GSNDWIPIENGFNYAIDLVKFIKETYGDYFCIGVAGYPEVHLTAQSRDHDIQSLKEKVDA
GADFIITQLFYDNQIFLEWVRDCRQAGIECQIIPGILPILGYDRFSRTINFCKTKVPQEI
LDNLQIIKNDDADVRKYGVAFGVQQCQELIDNGIRFLHFYTMNLEAAVIKIIEGLKILDN
QKSLPFKKPSCRQSEEVRPIFWAIKPKSYISRTQEWDEFPNGRWGVSRSPAFGEPEMYGS
IAKKISFNFDELKKIYGENVSSYAEIGDLFVRYLKGEVKKYPFSEGSLQLETNVILDQLV
QINKNYVFTINSQPKVNGVPSTDPKFGWGPKNGYVYQKAYIEFFIPSEMIQPLINHLDKY
EMITYQAINNQGDEIKNVCKDDVNAVTWGVFKAKEIIQPTVVDHKAFLIWKKEAFQSWLD
HWAIIYGLDSYQFNFLQKCQNNFFLVNVVDNDYINGDLYKVFVDFIEENMELINQL
>A0A7G8JQS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. PROS-9-1|TrEMBL
MSSALQSSLEAGAITITAEVMPPRGGDPSHALKMASALKGLVHAVNVTDGSRAVMRMSSL
AVARLLLDQGIEPVLQMACRDRNRIAIQADLLGAHALGIRNLLCLTGDPVRAGDQPKARP
VNELESVRLLQQVTAFNRGEDPVKGDLADGPTDLFAGAAADPQCSSWSGLLRRMERKKAA
GARFIQTQMVMDASVLERFCREIAEPMELPVLVGVFLLKSARNAGFINRMVPGACIPDNL
IARLEAAADPAAEGIQIAAEQVQRYLGVAQGVHLMAIKAEERIPAILNQAGVNLPG
>A0A7C6UKN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterales bacterium|TrEMBL
MLIKDIFLSKTPVISFEIFPPKREYPIETVYETIESLNKLKPDFISVTYGAGGSSRDRTV
EIASTIKNKYGIEALAHLTCLSSSKEDIQTILMELRQNQVENILALRGDIPSEGLKGEPY
FNFAKELVSFIKSEGGFCIGAAAYPEGHVECASLDKDIQYLQEKVQCGVDFLITQLFFDN
KRFYEYKDKLVQKGINVPVMAGIMPVLNKNQIKKMVSLSGASLPNNIIRILDKYEHSPEA
LREAGIAYATEQIIDLLSWGADGIHIYTMNKPDVADTILNNLSQIRSVLTKENHC
>A0A1I6UBK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. BC26|TrEMBL
MDSLLREKILRREPGITTYGMTPPKESNTAEKIAEIAQKQVERLEGLQIDGLILYDVQEE
SDRIEQDRPFPYLRTVDPTTYSNEYLNQLAVPKIIYRCVGNYSANQFSEWLQAESDQDRF
SVYVGASSSKQATSMRLPEAYELSQRMDPNLTFGGVVIPERHTMKNDEHLRVIQKMNSGC
QFFISQATYNIEATKNFLSDYYYSCRDQEIDMVPILINVAPCGSPKTLEFMKWLGISIPK
WLENDLKHSNDILDKSVTLSHRMFEEIFDFGLEKGIPLGCSVESVSTRKVEIDASVALLN
EIRATIAKKLVK
>A0A7J9WKL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitriliruptorales bacterium|TrEMBL
MGDALRRGRAGVRRTRRLTAEPRTPDRVAETARSASPYSDGLEVDVGQKGGSGVRGLGPL
LGKGPLVADGGTGTSLVERGVSLGECFEWRNLTDPDLVATVHQAFVDAGARLVETNTFGA
NRFKLARHGLADRVAELNRAGVELGRVTGAPVAGSVGPLGVYLAPYGRVQPAEAFATYAE
QIAALAEAGADLIAIETQTDLTEAEQALAAARDTCDLPVLVSMTFTRDDRILLGATAAHV
GERLAAAGADAIGVNCSQGPAQVLRLIETLRSVVGEVPLVARPNAGGPAAVGGRLLYPAT
PEYFAEYARALAAAGVRLVGGCCGTGPAHIAAMGQALAGAAGSKRADAPVVDVLPPARSD
PGMGTGTEPTRFAAALHAGRLAIAVEMDPPRSASPARLLAGAETLADAGADVITVADSPM
ARMRMSPWGACRLIQEHVGVETVLHFPTRGRNILRIQGDLLATHTLGIRNVFVCMGDPTS
IGDHPEAASNIDVAPSALIALISRCFNAGVDQGGASIGEATSFLTGCALNLAAPDLEREC
RVLRRKIEAGADFALTQPVYDRAVLHDFRAAYEVEHGPLTLPLLVGVLPLVSARHAEFLH
NEVPGVDIPAALRDRIRRAADRAAAEGARIATDLALALARDAAGLYLMPPFDRYGLAAEI
VDAVRAVQPTPTIRH
>A0A374I511|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. TF10-5|TrEMBL
MKVSEILKKNEVTISCEIFPPKQGAQLQNYKAIAAEIAKLKPAYISCTYGATGGTSDYTV
EIADAINSYGVPAIAHLTCVSSTREKVHTVIYELKERGIENILALRGDIPTNTDFPLPDQ
YHHAIELIREIREAGDFCIGGACYPEGHPEAANMNEDLDHLKEKVDAGCEYLTTQMFFDN
NIYYRFLYKALAKGIDVPVTAGIMPVTNAAQVKRTISLTGNLVPAKFLSIVDRFGDNPAA
MKQAGIAYATEQIIDLIANGVNHIHIYSMNKPDVAAAIMNNLSQIYVREQA
>A0A2W6VM13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MPAQLHLRTASRRCPKRMVYGPCGGVQADGGCEVPGASCAFLAEPASLASLAFDPGDIAP
PPGALESGDALRELPRLAAADAFAARVRAGGVITTDLPVHGTDVGVLADAGARLAGLTAV
IAGEPPGLREALSPTHKSLVLQRAGATVIAGITCRDRNRVALEGELAALADIGVAGILAV
TGDHPASTALPEAEAVFDLDSTRVAALGRRAGLFVAVAEQPIAPPVAFRPHRLALKARAG
AELGILNLCGNLDAVAAFAAAVAAEGTPIPLLAPIPVITSARAGARLAALPAVALPTGLA
ATVSSSRDPLQTGIVAAAEAAHQALSIPGIAGIHLSVIRDDETDPTGLAAVDAAARTAQL
IREAIA
>A0A1R1LSQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Motiliproteus sp. MSK22-1|TrEMBL
MIFPDEPNPGEMLPILPGHTTGGRLERVLRAGHFAVTSELAPPDSANPEDVYARARVFDG
YVDGMNATDGSGANCHMSSVGMCALLTRIGYAPVMQVSCRDKNRIAIQGDVLGGAAMGVT
NILCLSGDGVQSGDHPEAKPVFDLDSMSLLETIRTMRDKSEFLSGRKITDPPKVFLGAAA
NPFAPPYDFRPHRMAKKIAAGAQFIQTQYCFDIPRFKEFMARSRDLGLLEKVFVLPGVGP
MASARTATWIRNNVPGIHIPDAVIKRLAGAQDQKKEGQQICIDLIQELREIEGVSGVHVM
AYRQEESVAEIIDRSGVLEGRVPWYPGRDQELQKERA
>A0A1V3QPU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. B04|TrEMBL
MPAISFEFFPPKTDEQRTQLDRAAQVLKAYRPEYASVTFGAGGSTLSYTGDTVARLHARH
GLNVAPHLSCVGGTRAELAALLDEYRAAGYRRIVALRGDMPSGMATAGDFRYAAELVGFI
REHCGDHFHIEVAAYPETHPQADDALRDLQHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VRRLGVNVPIVPGIMPIANYTQLKRFSDMCGAEIPRWIAKRMQAHGDDADSIRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRARATQSVLQQLA
>A0A5I4KJX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Aberdeen|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1J5T0R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MLFDKIRNRENGIVLYGMVPPKRETPPEKVEEISLRQVQRLQSLKIDGLILYDIHDEKSR
TPEERPFPFIETIDPFLYSNNYLSALCIPKVIYRSVGKYSKSELSRFLAEASPENNLTVL
VGASSNSQEVTISLIEAYKLKREINRDLLMGGVTIPERHLSKGNEHVRVFDKIFRGCSFF
VSQGVWDLNASKSFLSDYYYYGQEHNVPLVPIIFTLTPCGSLKTLQFMRWLGISIPRWLE
NELTHAKDILQQSVEFSEQCWLELKHFADQKGIPVGCNIESIAVRQAEVEASIELLQRVT
KQ
>A0A0B5CZI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium humireducens NBRC 106098 = DSM 45392|TrEMBL
MNANAPQYSAKRRFSASAPLDTFDPEEWRQAPVPERTSLSFEVMPPRHDADEAKIDELLD
TLQSYNPDYISVTSSRNSGWLEGTAKFIAKISAQTRIPTVAHLACTAGTREELIGWINRL
MDSGVRGLLALRGDLAEGQTGMPEGYLKHATDLINLIQEIEEEQVARFGAGRLAIGVAAY
PSGHEESTSRDEDIDVLLAKQRLGADFAITQLFFDAEDYLRFLERARLAGVRIPLIPGIM
PMTSVARLRRMGQLSGLTVPDRLISRLEAAGPESEYQTGLDLTAELAQTILDAGAGGMHV
YTFNRPDTTTELLDRIGITPDPRVRE
>A0A7Z1NGB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. cynarae|TrEMBL
MYPDTPSLASTVTDAYSLEVSATDIPGLTAAAPRIMRGSTIAIPYLPSQDNDARLAAAQS
VRALGFAPMPHLSARRITSLEELHAFVRRAVDDAGVERCLVIAGDAPSAIGPFPDSVSLI
TTGVFERAGIKTIGVAGHPEGHPGMPATDQWDVLERKCRSIAERGMAPLIVTQFAFDADI
VLTWLEALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACASMLSKYGISIGKLFGSA
GPDCFVDRLATGLTEAHGDVSLHFFPFGGIAQSVAWVEQYRSRTAAHIL
>A0A3C0QFB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistaceae bacterium|TrEMBL
MRDYFEQIRPTMTFEIFPPKGSGDLASIFATVDALASLAPDLISVTYGAAGGTSRENTVE
IASQIQNSYAIPALAHLTCAGNSKDEVDPVLRTLSENGVRNILALRGDIAEGEQLNDFRY
ASDLISYIKSKYDFRIFAACYPEKHIEAYSMEDDLRCLKEKADCGVDVLISQLFFDNELF
YRFRDQARSIGIDIPIVAGIMPITSSSQISRMVSMCGATVPEKVQKIIRAFGHNSMAMKE
AGIAYATAQIVDLLSTGVDGIHLYTMNQPDIAKRISENIRGILYSLRVKRA
>A0A484HHQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacteraceae bacterium|TrEMBL
MNFQKKISSGEFVVLAEMDTPKGVDISELIINVRRIQGRVDAVVIPGMDSGVMRMSAIGG
GALTRREGMEAVIHVCCRDRNRMALQGDILAAHALGIRNVVVVPAESMEKGDHRDAKPSD
DLDETELVRAIRSLNSGTDMSGFELNGRPGMTIGCAISPFGNEKEMARQLKLANEKVRAG
AEFVITPPVFDLERFKSFFENAKLLGVPVIPTVFLLKSVGIARYMANYEPGAHISEDMIR
RIRKAPDREQECLKIAGETIAALRDVAQGVKIQTLGWESHLPAILRWAGI
>A0A0J7JDI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter subterrani|TrEMBL
MTLVSERQAFNRPDEEAAERFRDLVRSASIEATPRQILTTEHLPDLLPARTCVYVPFLPR
GQFRDTLEASRRLLALGMQPVPHVPARMAQSREQLRDWLAQLNESGVDRLLLIAGDSDAV
AGPFPDTLAVLESGLLAQFRFHGIGVAAHPDGHPMADRATLTQALSIKRDYARTTATRLW
VVTQFTFDAEVVIDWLQGLGNVLEEVPVYIGMAGPTRVKTLIAYAAMCGVGASARMLLRR
PGSARMLGAWKPDDLVRALVRYCLENPETLLRGIHLFPFGGLRQSAQWIRDHSGSFEDKR
EAVP
>A0A2N0V4V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas sp. Kb3|TrEMBL
MNISFEIVPRSLEAFDQQYAFVQTLDKGINIINVPDIQRFDTRSWELATRVDRSKYRFIP
HFRAIDFKIDSGELYRIIEEYALDSVLLVSGDPPEGLKRSFYNTDVVDLIRAVRQRFPNL
NIYAGFDPHRSGVQDECDYIQRKVDAGAGGFFSQPFYDSRMIDIYAEHMQGLETYIGISP
ITSKASMNYWEVKNKVKFPKRFRPDYDWNVEFANGVIASAAANGLNVYFMPIRIDLARYF
GAIKLGG
>A0A1J5SIE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MPANPSISSLFEQKRPLRSLEFFPPKDDAGMDALRQTAAAVAKIDWDFVSVTYGAGGSTR
QRTAQVSQVLKDDCGLTVMPHLTCVGHSRAELASIADTLHAEGFRNIMALRGDPPKGAAE
FKVAPDGLNHANELVSLLKERHADFCLGVAGYPEKHPEAPDFRTDLDNLKRKVDAGAAFV
TTQLFFENDRYYRFVDHCHAAGIRVPIVPGIMPVLSFKQIQRITSLCGAALPAPLARRLE
IAEGSPDVVEIIGIDWALTQIRDLLRHGAPGYHLYILNRAKGALALAAGLSD
>A0A086MJS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga sp. BSC39|TrEMBL
MSPLTLRPSRQASRPIKVSFEFFPPKTPEMEATLWSSIQRLAPLNPQFVSVTYGAGGSTR
ERTHATVSRLVQETDLKPAAHLTCVAATKDEVDDVVRSYWDAGVRHIVALRGDPVSGIGT
AYEAHPGGYQQTCDLVAGIKAIGDFEVSVSAYPEKHPEASSLDADIDALQAKVDCGADRA
ITQFFFDNDHYFRFLDRVHARGISIPIVPGIVPVQNFKQTANFASKTGASVPAWLAARFD
GLDNDVETRKLVAAAVAAEQVIDLVDRGVSEFHFYTMNRADLVYAICHLLGLRDHSVKAA
A
>I0X8H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp. JC4|TrEMBL
MKISEILKKNEPTLSFEVFPPKTSDKFDTVEAAANQIADLRPHFMSVTYGAAGTTRGFTT
EIAASVLKHGATPLAHLTCVNASRASTKEQLDSLKSHGIENILALRGDIPEGSNPSEWEF
KHAHELMDFIKQNGDFCVGGACYPEKHPESSNVNDDIRSLKIKQDAGCSFLTTQMFFDNS
TFYNFLFKVREAGVTIPVIAGIMPVTNANQMAKIIKLSGAFIPRRYVALLDRWSSDPIAL
KQAAIAYATDQIIDLIANGVNHIHIYTMNKPEVAAKIQENLSSIIKKPE
>A0A327W807|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga dinghuensis|TrEMBL
MKVTEHIAQAKDTLISFEVLPPLKGKSIESIYEHLDPLMEFKPAYINVTYHRSEHMFKKK
ADGSFEKVEIRKRPGTVGICAALMNHYNVDTVPHLICGGFSREETENALIDLAFIGIDNV
LVLRGDAPKNEAFFEPDPHGHSYASELLEQVVRMNNGIYLEDDLQGGVKTKFCVGVAGYP
EKHFEAPNMQTDLMNLKRKVEGGADYIVTQMFFDNQKYFDFVEKCREIGITVPIIPGLKP
LTSRKQLSILPRIFNVDIPTEFSNEILKCKTDKEVEELGTEWLINQSKELKKFGVPILHY
YTLGKPKVVRNAVAAIM
>A0A1W1H501|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfamplus magnetovallimortis|TrEMBL
MNLKTSSKLEKVLKSGHIAVTSECGPPRGSDPKAVTEKGKLIKDHVDVVNITDNQTAMTR
MCSLAACIHLKQMGIEPMLQMVTRDRNRIALQSDILGAASFDIHNMLCLSGDHQSFGDCA
QGQNVHDIDSMQLLQTVRHMRDNGKFLGGDDIKRPPDIFVGAAANPFADPFEVRVPRLAK
KVACGAEFIQTQCIYNLDKFEEWMRRVRERGLHEKVFILAGMTPMKSAGMARYMKNRVPG
MDVPDEVISRMAGVPKERQPQEGIDICVEAIQRLKEVEGVAGFHIMAIEWEEKVPEIVER
SGLYPRPQV
>A0A255HWC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. PC23-8|TrEMBL
MATHNFSIEFFPPKTPEGAEKLRATRARLSELQPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRASIRAVLGEFQAAGVNRIVALRGDLPSGYGASGEFRYASELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLQAFARKVQAGADAAITQYFYNADAYFQFVE
QAQKIGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTSLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>J2YGI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM24|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>R9B3U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter tandoii DSM 14970 = CIP 107469|TrEMBL
MSIFIFYNKLLSFLTFVTHLPDMMPLLTDSLQNQPFSIFLEYLPTKHAQLVPSCIAGYPV
TMTIADRVRSDDDPEPLAIAQNYAAEIPKILHFSGKGRDIADFNEFIRAIQEQGYSNVLL
LTGDKLKHHQDGQDVNLPRTRYLESVNAVMQAKKLAPQIKVGVALNPFKYAKAEHDAQYF
KLDKKVQAGADYVVTQLGFDLDALKEAKQYLNKLPSCLDLFACVMPLTVARAEFMVKHKV
AGIVLTPHLLQLLKHEQSVDAVIAEQNVYARCALQILICRFWGFAGVHLSACHKAEEQKK
LEQALERFQDFSFEQCMQIWSELHQLKSGDELKPKSDVFQKKVSSEQMLKYKSMQFMHDS
MFDSKIARNVGRKLFNPKLWSGYFANKLLIKSEYLSKHGVVGCESCGQCRLADTLYICPE
TCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAEQTNQIAILKERLIDTVPIELRGTS
SWVNWFNPK
>A0A8D3WJD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces pratensis (strain ATCC 33331 / IAF-45CD)|TrEMBL
MALGTPSTRTDHARTVRELLATGETSFSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVRYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDSDIGHFVD
KCRAGADYAITQMFFQPESYLQMRDRVVAAGCETPVIPEVMPLTSVKQLERFAQLSNASL
PSALKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A844XR00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania vulgaris|TrEMBL
MERPLFSGLPGDIEVSFEFFPPKTEKMGETLWQSVETLAPLNPRFLSVTYGAGGSTRERT
HQAVRRIVNETAIPAAAHLTCVDATREEVDQVAREYWEEGVRHIVALRGDAPSGSQGYAP
HPGGYENAADLIAGLKKIADFEISVAAYPEVHPDSSDRQTDLDNLKRKFDAGATRAITQF
FFEPECFFDFRDKTAAAGIEGEIVPGIMPVLSFAAVQRMSGLCGTAIPEWMGGLFDGLDE
RPEARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKA
>A0A7W5G7P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas organivorans|TrEMBL
MSAQEHPLGISFEFFPPNTDAGREKLMHARDALASRRPRFFSVTYGAGGSTQHRTLNTVR
AVRESGFNTAPHLSCIGSEKAALRDLLAQYREEGIDSLVALRGDLPSGMGGVGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFDRDVENFARKMKAGADLAITQYFFTADAYF
HFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSAAIAAF
GEEVISRLCQRLLDGGAPGLHFYTLNQAEPTLKVLDNVCG
>R6G3E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odoribacter splanchnicus CAG:14|TrEMBL
MTKVIDIINQKKAPFASFELVPPLKGSDINKLYGAIEPLMEFAPPFINITFHRDEVEFRQ
TADGTFEKVTITKRPGSVAIAAAIMKRFPVEVVPHLICGGASKHQIENDLIDLNFLDIQN
VVALRGDAIPGQKYFVPEPDGHRYSCELVGQIHNMNRGIYLDECLKNAVPTNFCIGVAAY
PEKHYEAPNIDIDIENLKRKVDAGADYIVTQMFFDNTRFYEFTAKCRAAGITVPIIPGLK
PISTQTHIEMLPRAFSIDLPQELMNEVRKCKDNKAIYQVGIEWCTAQSKDLLAHGAPAIH
YYTMGKADNIREILKRTF
>A0A239MUS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces glauciniger|TrEMBL
MTQSADRTITVDDIVRNASVEIIPLKGAEEKAAVVPADTTVTVTCSPKFGLLRTLNHVAA
ARRSGHRVVPHLAARMVEERQDLRNFVRRINDLGVDELFVIGGDGEEPVGRFSEAAEILQ
ELGEFDHGLSKIGIGCYPEGHPKISDDVLFDALVRKQQYADYMVSQLCFDASAMAGWLQS
ARDRGVTLPLRIGVAAPLQVRKLIELSVKIGVGRSVRFLSKQHGMVGNLLLGRAYEPMDL
LIAIHKKISFADLSIEGLHLFSFNQVDTTVDWLSRASGVEETG
>R5DAE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides johnsonii CAG:246|TrEMBL
MKVIDLINSSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQKTDIYHEHATDLQQQVNDFNKGIAIDGSAFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDDEAKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVYKVAKEVY
>A0A5N6M5B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mikania micrantha|TrEMBL
MKVIEKILESTAAGDAGKTVFSFEFFPPKTEEGVENLFERMERMVAHNPTFCDITWGAGG
STAELTLEIARRMQNLVCVETMMHLTCTNMPVEKIDHALETIKKDGIQNVLALRGDPPRG
QDKFVQIQGGFACALDLVEHIRKSYEAHPEVIESNGLATPEAYANDLAYLKRKVDAGADV
IVTQLFYDVDNFLKFIPSEITAALEPIKDNEEAVRAYGVQLGTEMCKKIMASGIKTLHLY
TLNMEKSALGILTNLGLIEESKISRPLPWRRPTNLFRLKEDVRPIFWANRPKSYITRTTG
WEQYPHGRWGNASNASYGALTDHQKFMKYCLGQLKTSPWSELDALQPETKIIDEQLASIN
LKGFLTINSQPPVNGAKSELPSVGWGPAGGYVYQKAYVEFFCSGDKLNALVEKSKAYPSL
TYVAVNKDGNLVSNVGINDVNAVTWGVFPAKEIIQPTVVDPSSFLIWKDEAFEIWSRGWA
QLYSEDDSSRTLLQEVQNTYYLVSLVDNDYINSNLFTVFKDF
>A0A2E6Z8D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rheinheimera sp|TrEMBL
MAFANARYLDAINRNLHDVQGKVNVSFEFFPPKTPQMEQTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASKQQLIDIARDYWQNGIRHIVALRGD
LPSDSAAIPELYAADLVEILRSVADFDISVAAYPEVHPQAPNAQFDLLNLKRKVEAGASR
AITQFFFDIEKFLRYRDRCAAIGIDVDIIPGILPVTNFQQLQKFAGLTNVAIPHWMNKAY
QGLESDPTTRNLVGANIAMEMVKVLSQEGVDQFHFYTLNRSELSYAICHLLGARPML
>A0A248YQP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plantactinospora sp. KBS50|TrEMBL
MALGLPSVLPRSQPSIGELVRCGPTFSFEFFPPKTADGERLLWQAIRELEPLLPSFVSVT
YGAGGSSRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRNVVGRLAAVGVRNILAVRG
DPPGNPNGEWVQHPAGVLYAEELVRLIREAGDFSVGVAAFPYKHPRSPDIEADTRNFIRK
CRAGADFAITQMFFDADDYLRLRDRVAAGGCDTPILAGVMPVTQMGTIERSEKLSGAPFP
RHLAERFDRIADDPVAVRRLGIEVADEMCRRLLDEGIPGIHFITLNRSTATREVWHQLRD
>A0A2J6MM81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. WAC0059|TrEMBL
MKPLELSFEFFPPKTQDGVDRLRATRTQLARFKPKFVSVTFGAGGSTQQGTLDTVVDIAR
EGIEAAPHLSCIGSSKESLREILGEYRSHGIRHIVALRGDLPSGMGEVGELRYASELVRF
IREETGDTFHVEVAAYPEYHPQARSPRHDLEAFAQKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTDLCRRLVEAGVPGLHFYTLNGAGATAAICERLGA
>A0A859PJK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium Kacie_13|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDANRDELRQIAQDYWQSGIRHIVALRGD
LPAGSGKPEMYATDLVHLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPHWMNSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEIAVPV
RA
>G5GZA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas noxia F0398|TrEMBL
MAQNSADIREHIKKEPLVFDGGMGTYYAQKTHTHGKGVELANIETPAVVGAIHTEYLQAG
AQAIKTNTFAANRIVYQGDESLVRRIIRAGWEIAARAAEPFGAYVFADIGPVTGLPHTDI
IAEYRFLADTFLACGATHFLFETNASIEGLIETAAHVKRVCPHAFILASFSALPGGYTRD
GRFAEDLIHEAAESGSIDAVGFNCVNGVRQMRELVHHLGMTSLPLSLMPNAGHPIVVDGR
TFYESAPEYFGTSLAAIVRDGISIVGGCCGTTPEHIRALCAALADGTGEIDEEGEETRVQ
PMEVPLSPFFDALKSGGKPIAVELDPPETGNADKFLVGVRELQAAGISAITIADNPIARA
RMDAAMLAGRVHRELGIEPIPHMTCRDRNLNAIKSILLGLSAEGVHNMIAITGDPIPTAE
RDEVKSVYQFNSRKLASFVMSLGSRGDIVPFHVFGALNVNAKHFPSQLGLARKKMEAGMT
GFFTQPVLSERAKENLQTARDMLPGAFILGGIMPVVSERNARFMESEIVGIHVEERIISA
YRGLDRTAAEELAVRLSLAIAKDIEPYIDGYYIITPFSRTALIARIVEGIKERGEIR
>A0A7W0EUN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MHLQSKFDSGEFLYLAEIEPPKGVDVSDMLKNAKQLKGKIDAFIVPEMSNAVMRMSSLGA
SLLLKNNGLNPIFQVCCRDRNRLALQADLLAAGAAGITHVMAVAGEDPSFGDHHQTKAVY
DIDLMGLLKGIQQLQEGRDMAGIDLSGAPKFVVGSTLNSGLSGQALEMELKEMSAKMAGG
VSFFITPPLFDISTMKSFLSRIDLSKTRIIPTVLLLKSVGMARYMARNVDHVHIPDEIIT
RIQKAPDKIRECVSIAAETLSTLKESGFGGAVLSTIGWEDKIPEILEKI
>A0A7V1WW66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSVKTPSKLEKILDSGQLAVTSECGPPRGSDPEAIRQKAEMIRNHVDAINITDNQTSVTR
LCSLAACIHLKQMGLEPTLQMVVRDRNRIALQSDILGAASFDIYNILCLTGDHQTFGDCP
QGQNVFDIDSMQLIQTVRRMRDEGKFLGGDDIKRPPQMFVGAAANPFADPFEIRVPRLAK
KIAAGAEFIQTQCIYNLDKFELWMRMARDRGLHEKVHIMAGVTPFKSAGMAKYMKNRVPG
MDVPDDVVKRMAGVPKEKQPDEGIDICVETIQRLKECEGVRGFHIMAIEWEEKVPEIVER
SGLYPRPGD
>A0A0F5ZSL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grimontia sp. AD028|TrEMBL
MNFEQGKVDCMPQLPDPAFAAAELVYHASLEATPRQVSALENRPEWLPEGIRVYVPFLPS
SNFEDAFETCKTLLIWGVVPVPHLPARAVPSEEKLREWLLALKVLGVKQLLLISGDIETV
QGPYADTMQLLQSGLLQEYGIESFGVAGYPEGHPHAEQATLKRALEFKRNYAKTHGLSLW
VVTQFSFDQTVLEQWLDEHQTILAGIPVYLGLAGPTRLKNLLSYAAQCGVATSAKALTKN
INAVRLLRPWTPDSLLEGLAIYQSNRSESVLKGIHLFPFGGLKQSAEWLANKAR
>A0A1N6TJZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. RU35A|TrEMBL
MNPVAKAPRSESALRVSFEFFPPKSPDMEQQLWQTVRELARYNPDFVSVTYGAGGTTKAP
TFSTVERMIGEMRLPTASHLTCVDADKAETHQVIADLRKLGVRHIVALRGDPASGIGTAY
QPHPQGYANAAELVAGLKEIGGFEISVSAYPEKHPESADVSADIAMLKRKADAGADRALT
QFFFDNDVFERYLDQVRAAGITIPVIPGIMPIQNLTQLKRFASRCGSTVPAFLDARFEGL
DDKPEDRAKVAADVAAEQIEDLMRRGIFDVHLYTMNRTPLVASVLHRLGILPVEAAQAGA
AA
>A0A2H1JCF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MSQEVLASLLKSARYEILPTAGVVDRVHEYVVPGRVITVTASTGLTLEATLSTVEQLQAL
GFTAVPHIAARMVQGRTELEEIVDRLTQAGIDRIFVPAGDATPPAGGYAGALDLIIDLAS
MAAPIQHLGVGAYPETHPLIPDDVTVQAMWDKRDYATHLVSNLCFDPGTIATWLARVRAR
GIDLPLILGIAGKVELAKLARVATKIGVGESTRFLRKNTVTFTKMAKPGGYNPRKFLDKL
APVLDNPSMGVAGLHIYTFNQIKDTEIWRRRQLAALGHNDEVPSTS
>A0A5B7UCY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia sp. JS20170427COW|TrEMBL
MKITEHLYNAQGKTLFSFEIVPPEKGVGINDLYKNIDPLMEFNPPFIDVTTSREEYVFLE
REGGLMERKVTRMRPGTLGICAAIQHKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDTMKGEKYFTATKGGNRYASDLVKQIENTGKGKYLHSDTACGEENKFCIGVAGY
PEKHIEAPSMNYDLEMLKKKVDNGADYIVTQMFFDNQKYFQFVKEAREFGIDVPIIPGIK
PIATLKHLQLLPQVFKIDLPETLVNEVVKCKNNQEVRKVGIEWAIAQCRELLEHNAPVLH
FYSMGKSDNILKIAQEMF
>A0A2A3CX72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3864|TrEMBL
MEKAAIRPSAIDASIEMAPSQVIDSPDLPGLFPSGVRVYITDIGLADTPTLVKAARRVAD
LGYTAVPHMAARRLTTRQALETRVKALAEEAGVRDLLIIGGDVATPAGSFSSSFEVLETG
FVDRYGITEVGVAGHPEGSRDFGDEAAIAALRMKSAWAERTGAKMRVVTQFGFDADKFIA
WADGLAVSGVDLPIHLGVAGPAKITTLLKYAALCGVGNSLSFLKKRSASLAALATSHSPE
SFVGPIEHHVRAKPESAIALLHVFPFGGIKNTARWLYERGSWQGLEADDRSSIA
>A0A3N5FHB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKTESVLEKMLISGNLAVTSECGPPRGAVPEKVRQKAELLRGYVDAVNVTDNQTAMVRMS
SFAAAVILRQLGIHPILQMVTRDRNRLAMQSDIIGAYSHDINTMMCLSGDHPQFGDHPMA
ASVHDIDSIQFVQMVKKMRDEGKFQGGADIENAPKMFIGAAANPFADPFELRVARLAKKI
AAGADFIQTQCIYNLDKFEKWMEGVRNRGLHEKCYILAGVTPIKTVGMARYMKNKVPGMD
VPQAVVDRMAGVPKEKQAEEGIKICVETIERLKQVKGVAGFHIMAIEWEQKVAEIVKRAG
LYPRPDIGI
>A0A2N6C4P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKVNTPSKLEKILAAGHLAVTSECGPPRGSDMEVIVEKANLIKDHVDAINITDNQTSVTR
MSSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAAAFDIYNILCLSGDHQSFGDCP
TGQNVHDIDSMQLIQTVRHMRDDGKFLGGDDIKRPPRMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYDIDKFELWMKMARDRGLLEKVAILAGVTPFKSVGMARYMKNRVPG
IEVPDDMVKRMADTPKEKQPEEGVKICIESIERLKEVEGVRGFHVMAIEWEEMVPVIVEA
SGLYPRPSVE
>R9NZU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudozyma hubeiensis (strain SY62)|TrEMBL
MAAALDAGSAPSEASAVSRSDPAHITSKIKAASSQDVPFWSFEFFPPKTTQGLANLYNRI
ARMRANLDPSWIHVTWGAGGTTGGKSLELAGRIQKGKLDPDVELVQTEVKQIRSGSDQHI
ENVKGGEAWEEKSADACDVCLHLTCTNVEKSSLDETLETAKRLGIKNILALRGDPPRGEE
YWVAADDRFQHATDLVRYIRDTHGDHFCIGVAGYPEGHADYVDRDVKRDLRYLKTKQDAG
AQYIVTQLFYDVDRFLAWYKECRDIGITIPILPGIMPIQNYSSFRRMTNLCKVQVPQLVL
DALEPIKSDDAAVKEYGVSLSIHMVGRIFLETDVRGFHLCSLNLEKSIERILEGLGWKTD
LGAQPEADARMKGIPSHIRLERTKNQMLSDRTGANTPKDFKVTTQEALARTLARTSSSYQ
VPETSTWDEFPNGRYGDSRSPAFGEMDGYGVSLKVPPQDALRIWGHPVTLSDISTIFASY
LEEKISCIPWCDAPLMNETLQIRDHLLSLNRLGEGKNASGKGWWSVGSQPAVDGAPSTDP
VVGFGPPGGFIFQKSFVELFMSTSDKDQLVSRIDALGSKAQITYFAGNARGDFQSNLGDE
EANTVTWAVFPGKEIVQSTIIERQSFEAWREEAFEIWAEWSLLFPKQSASRRLIEEVKDG
RWLVTVVHHDYKQSDALWQFLAQ
>A0A3A5ATV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKTQSVLEKVLETGNLAVTSECGPPRGALPEKVKEKAGKLKGYVDAVNVTDNQTAMVRMS
SFAACLILRQMGLNPVLQMVTRDRNRLAMQSDIIGAYSHDIHTMLCLSGDHPCFGDHPMA
ANVYDMDSIQFVQMVRRMRDEGKFQGGEEILNAPRMYIGAAANPFADPFELRVARLAKKV
RAGADFIQTQCIYNLERFGKWMEGIRDRGLDEKVHILAGVTPLKTAGMAKYMKNKVPGMD
VPDSLIKRMSGVPKERQAEEGIRICVETIQALKEVKGVHGFHVMAIEWEERVPEIVERAG
LYPRPLV
>A0A165IFE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp. HI0044|TrEMBL
MQRISFEFFPPKTEQGKEKLLATQKKLLAKNPAFFSCTFGAGGSTRDNTRDMVNKLREQH
GDTAPHLSCIGQSKEEILELVNGYKDAGVTRIVALRGDLPSGMGYAQSEIKYADELVALI
RQETGDHFQLEVAAYPEMHPQARSFEDDIAHFKRKMDAGANSGLTQYFYNADAYGYYMDA
LQKTGCDAPVYPGIMPILNVANLLRFSNTCGADVPRWLQSKLNDIKDDDAAVKAFGEEVV
TRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGM
>A0A525CRI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKTDSRLEKVFASGNLAVTSEAGPPRGADPEKVKEKAKHLDGYVDGVNITDNQTAMVRMS
SMAASVIVKQMGMDPILQMVARDRNRLAIQADILGAYSLGINTMLCLSGDHPKFGDHPTA
SGVYDIDSVQMVQCVRKMRDEGKFQGGADITKPPKMFIGAAANPFADPFELRVLRLAKKA
RAGADFVQTQCIFNLDKFEEYMKMVCDMGLDEQIHVMAGITPMKSAGMAKYMKNKVPGMD
VPDEVIKRIEGVPKADQAKEGVTMAVEFIERLKECKGVHGFHIMAIEWEEQVPEIVERAG
LYPRPEL
>A0A7C3G1X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanithermus sp|TrEMBL
MTLREKLAAGRFVVTAEVDPPRGTAIERTLEEVREVAPLVDAVNLSDAPMANLRMSPFVI
ARLVEEKTGVEAIPHLTARDRNTLALQAELLGASAIGVKNVLLLGGDPPERGDHPFAKPV
YEVGAVELIRLAEGLNQGRNWAGGVLEGKTALFLGAAANPGARDLAQEAEKTHAKIEAGA
RFFQTQPVFSLDEVEAFLKALGPVPKGVFFLFGVLPLVSARMAERVAAWARVPGALVAAL
EKEGAAAGYAWARRTVAELRAAGMAGVHLFPLGRPGRVARVLHSASSSGAEQPGS
>A0A8C3H045|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corvus moneduloides|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLRDKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFVITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKVSPPFCWIHCCDAL
EVQKTLLSAVPMQGDYFSNYQPGKGQIAFILHS
>A0A7W6QBW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium aethiopicum|TrEMBL
MALKNEGRGRNFGISFEFFPPKSEEMEGQLWDTVAKLQDWDPDFVSVTYGAGGTTKAPTL
SAVTRFLAQTPLATASHLTCVGATKEETHQMIDTFRKVGVKHFVALRGDAPGGVGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEQVRAAGISIPIVPGIMPIQNLTQLKRFAGACGAVIPAFLDQRFAGFDD
KPEDRAKVAAEVAAEQIEDLVRRGIGDFHLYTMNRAPLVSAVLDNLGFSRRSAKSAGAAA
>A0A7W1HK52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MDLLDELQSRLVCGDGAMGTMLLNTGIPLERCLEELCVSDPDRVLEVHQAYVAAGARVIE
TNTFGASRVRLDRFGFGERTEEINAAAARVARKAAQGKDVYVAGSVGPLGISAGEAERRG
IDRIAVFREQITGLLDGGVDAIFLETFLDYDELALALEAKMHLSKAPTICSLACEQEGRL
PSGLTVVEAFGKLRDGGADIVGVNCLNGPQAMVHLLERIPLDFLLSAYPNAGYPKYHEGR
FIYYTSPDYFAKMAREMAAQGARLIGGCCGTTPRAIAAMAAALAGMEPVRSKTVGVITER
AHPPAPPSVAGPAEESLLDRIAAGHRVIICELDPPKTLALEKYFIGAQALVQAGCDAITL
ADNSLAILRVSNLAIGAMLKERFGIIPLLHMSCRDRNVLGLQSELLGMAALGMRHVLPLT
GDPARVGD
>A0A7V9ERD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MDLLDELQNRVVCGDGAMGTMLLDEGIPLERCLEELSLSEPDRVLKIHQAYVVAGARIIE
TNTFGASRVRLDRFGFGDRTREINAAAAQIARQAATGKDVYVAGSVGPLGITADEAETRG
IDRAAIFSEQITGLLDGGADAIFLETFLDDEEIELALQAKMGLSKVPAICSLACEQEGRL
PSGLTLVEAFRKLTALGADVVGVNCLNGPQATVHLLEHIPLDFLLSAYPNAGYPKYHEGR
FIYYTSPDYFAKMAREMAGQGARLIGGCCGTTPRTIAAMASALAGLEPIRRKAVSAVVEG
PRPSASRKVAPTEESLLDQIAAGHRVIICELDPPKTLALEKYFTGAQALVQAGCDAITLA
DNSLAILRVSNLAIGAMLKERFGITPLLHMSCRDRNVLGLQSELLGMAALGMRHILPLTG
DPARVGDHPGAASVYDVNSVQLIGIIKRMNEGFNYAGKSLNAGTQFVMGCTFNPNSRNLD
AQISRLERKIAAGAQYVMTQPVFDLRVLDEMARRTKQFGVPIFTGIWPLLSGRQAEFLHN
EVPGIVVPAEVRERMSGTEGAEGGKRGLEIAREICEAALERFPGVYLITPFLRYSATVEL
AAFARGL
>A0A7L8W7K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. KS 6|TrEMBL
MFIQSPSLSFEVFPPNPAVGNEKIMAVLKEMQDLAPHFISVTASNNKFNIEETTVRLADF
IRNDLHIPTIAHLPAVYLTKEMVSDTLEALDRVGVHKVLALRGDIFPNMEPKKDFTYATD
LIEYIKEQAPHFEIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYD
FQDKCVLAGIEVPIYAGIMPILNRNQVLRLLRTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSDTAHRIYQATHTFFDK
>A0A5K7YTL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina widdelii|TrEMBL
MLRIFKEDLTTPQNFVVTLELVPARESFGRSTETLLGIASDAFTDGRVSAVSITDNPGGN
PSLSPDVLGYEIFKLGLDVIVHFTCRDTNRMGMESRALQLARMGMKNVLALTGDYSGKGY
GGRGTPVFDLDSVLLTGMLKSLSGKMASSGDPDPFFTGCAVSPFKSLKAEQVAQYRKMDK
KIDAGASFVITQLGYNAQNFEDLIQYHTGKNAHIPIIGSVNLLSPRAARAMNRGRVPGVF
VSDELFNKVVSEWQEPRKGLKKAVERAAKLGAILKGLGFRGIHIGGVHRSFKTVAAILDR
MDQLQDAWPDYLGEFVQGKKKNSEDSDAQALPGGIKKEKASLKEMLLDHIPYKMLNSAHD
LFFNQSATMAPVYKSLASVLEKYNKTWVLKRCLEDPLKKTFLSCQSCGDCAIQHIGFLCP
ESGCPKHTRNGPCGGSTEGRCEVYPDQLCIWVRAYQRLAHVNSLATFLQDRVPPRRWELN
KTSSWVNFHLDKNIQSRMAGTRDQAASEIGSQGE
>A0A7W1P315|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MDLLDELQTRLVCGDGAMGTLLLERGVPLEGCFEEICISEPERVRRIHEQYIDAGARVIE
TNTFGANAVRLERFGFESRVMEINAAAARLARAAANNRDVAVAGSIGPLGITADEAASRG
IDRAECFRNQITGLLDGGAELLFFETFMDFGEMAVALQAKTEVSDAPAICSFACASEGRL
STGMPLVEAFGKLRTSGAAVMGVNCMNGPHGMVQLLERVPLDYPLAAYANAGYPKYHEGR
FIYHTAPDYFAQSAREMVAQGARLIGGCCGTNPTHIRAISEAIANLQPARSKRVRVIAEP
LPVRSATEEHAAEESLLDRMAGGHRVIICELDPPKTLALQKFFAGAQALVQAGCDAITLA
DNSLAILRVSNLAMAAMLKERFGITPLLHLSCRDRNVLGLQSELLGMAALGMRHVLPLTG
DPSRVGDHPGAASVYDVNSVELISIIKRLNGGFSHAGKSIKALTGFVIGCTFNPNARNMD
SQINRLERKVAAGAQYAMTQPVFDLRILEEMSRRTEHLQIPIFAGVWPLLSGRQAEFLHN
EVPGIVVPDDVRATMAGSEGIEGRARGVTLAKTITKAALAQFEGVYLITPFLRYETTVEL
AQFARGL
>A0A086GYI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces scabiei|TrEMBL
MRDMLATGRTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSVTYGAGGSTRAGTVKA
TEQIAADTTLTPVAHLTAVSHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWIAHP
QGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSPDWDSDVARFVDKCRAGADYAITQMFF
HPDSYLRLRDAVAKAGCETPVIPEVMPVTSVKMLERLPQLSNAAIPNALKERIVTAKDDP
AAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIHENLGPHHPPRA
>A0A2N8NJY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella sp. oral taxon 808|TrEMBL
MDRVIDLINHSRGTAFSFEILPPLKGNSIRSVYRVIDKLREFDPKYINITSHHGEAVEVR
GADGTVRTVNLRKRPGSVAIASAIQNRYGITAVPHLVCKGFTKDETEYGLIDLNFLEVNN
LLLLRGDTKRLREPDNPELYHAHATDLQRQVNNFNHGIALDGSPIADIETPFSYGMACYP
EMHEDARSMDDDIRYAKLKVEQGAEYLVTQMFFDNTKYYAFVDRMRAEGVTVPIIPGIKP
IVLRDQLEVIPRIFHCTFPPEFAAELGRCRTDEEATEVGVEWCTMQCRDLKAHGVPSIHF
YTLMASDSIRRVAREIY
>A0A4P7R1F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. PAMC26645|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGVSFEFFPPKSEKMDAQLWEAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATRAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPAEKVAAA
>A0A401IYR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium xenophagum|TrEMBL
MTLNDPAAPLYADLAGDCHVSFEFFPPKTEKMEAQLWSAIETLTPLQPKFVSVTYGAGGS
TRERTHNTVARIARETPLAAAAHLTCVGASKAEIGEIADAYWEAGVRHIVALRGDPPEVG
GTFEPHPEGYKGAAELVEGLMLRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFTPDAYFRFLDKTLAAGIKADIVPGIMPVSNFAATQRMAAMCNTQVPSWMGRLF
EGLDDHPASRQLVSATIAAELCRSLYGGGVRDFHFYTLNRAELSFAICHLLGLRATASNG
GTA
>A0A4T2A207|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas leptonychotis|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPAAPHLSCVGDSKAELRDLLNLYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFARKAKAGADSAITQYFFNADCYFY
FVERVRKLGIEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTDSIQAYG
EQVITEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>S4GYM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis JCP8151B|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNAAGVFNHASDL
VSYIRSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A2A2I791|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tamilnaduibacter salinus|TrEMBL
MKLVHEQAQGTDQGLILQDLAREASIEATPSQILDTHDVAGLLPGGTSVYVPFLPGADFQ
RTVDACRKLIGDGMHPVPHVPARAVESHDQLRDWLAGLTETGTHRIMLIAGDNDAPAGPF
DDTLGVLESGLLADHHIHQVGIAGHPDGHPVAGSDLITSAMARKRDYAIETGTHMWVVTQ
FAFDSDTFFEWLEQHCEVMTPMPVYFGLAGPTKLTTLIAYAARCGVGVSARMMKRRPSAA
RLLTSWTPDGLMQSIAQHVIDEPHSLLAGIHVFPFGGLERSAQWLHGLCREANELNQQPS
QAGV
>A0A4Y9RPQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacteraceae bacterium OM1|TrEMBL
MESHQLSIEFFPPKTAEGVEKLRSVRTQLAALQPQYFSVTFGAGGSTQQGTLDTVLEIKR
EGREAAPHISCIGTSRETLHGLLEQYKAAGIRRLVALRGDMPSGYGTGFANEFRYANELI
EFIRAETGDWFHIEVAAYPEMHPQAKSPQDDLQNFARKVKAGADSAITQYFYNADAYFRF
VDEARKAGANVPVVAGIMPITNYSQLSRFSDMCGAEIPRWIRLKLASFGDDAASIKAFGL
DVVSELCEKLLAGGAPGLHFYTLNQANATLEICRRLGVSA
>X6G6F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L2C085B000|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A2E4CW24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citromicrobium sp|TrEMBL
MTAQPTPPLAHGLDPAQERTRAKNDPLFSGLPGDIDASFEFFPPKNEKMEESLWNAVQEL
KPLDPHFVSVTYGAGGSTRERTHKTVARIIQEAGLPAAAHLTCVNASRKETQRIAEQYWE
AGVRHIVALRGDMPQEDGSLGPFKPHPEGYNSAEELVHGLKEVADFEISVSAYPEMHPDA
KSQQEEIDYLKRKIDAGADRAITQFFFSPNTFFDYLEKTDKAGIDVPIVPGVLPITNVAK
ARQFAGQNGAEFPDWMDDLFEGLDDRPSARKLVAATVAGEMCRRLYAGGIRHYHFYTLNR
ADLAYSICHLLGMRPKGEGEKTA
>A0A1N6UZK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium kushneri|TrEMBL
MKIKSIFDEKEVVFSLEVFPPRADVPIENIYQTLEELKDIDPDYISVTYGAGGGVHKNRT
CELSSIIKEKYKVEALAHLTCINSDQRTLNKILARLKAKNIDNVLALRGDKPVDGDPLGD
YNYAYQLVEHIKQQTNFGIAAACYPEGHLETESLDQDIEYLKQKVDYGVDYLISQMFFDN
SLFYKFRDKVEEKGINVPIEAGIMPVINKKQVGRIIELSDAYFPDKFQKILDKYEDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKVG
>A0A0A0EED6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudooceanicola atlanticus|TrEMBL
MTTPAVSFEFFPPKNLEASFRLWDTVQVLSPLNPNFVSVTYGAGGTTRDLTRDAVATLHK
NAGLNVAAHLTCVNATREETLAIADGFAEAGVTEIVALRGDPPKGEGKFTPHPDGFANSV
ELIEALADKGKFKIHVGAYPERHPDAVSDTSDVDWLKRKLDAGATDGITQFFFETETFLR
FRDRCEKAGITAPIIPGILPIENWKGMRKFAIGCGAHVPAWLDDAFDKAARDNREDLLAT
ALCTEMCTALIDEGVDKLHFYTLNKPELTRDVCHALGVTPEVDLRDVA
>A0A2E9HGK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citromicrobium sp|TrEMBL
MTGRTNHSHDGNRDASRSASEPLFGGLPGDIDVSFEFFPPKSEKMEAQLWDAVTELKPLG
PQFVSVTYGAGGSTRERTHKTVARIIAEAGIPAAAHLTCVDASRKETQRIAEHYWEAGVR
HIVALRGDMPREDGTLGPFEPHPDGYANAEELVRGLKEVADFEISVSAYPECHPDAQSPQ
AEIDYLKRKIDAGADRAITQFFFSPETFFAFLEKTDKAGIDVPIVPGILPITNVAKAREF
AGQCGAEIPQWMDNLFEGLDRRPAARQLVSATIAAEMCRRLYAGGIRHYHFYTLNRADLA
YAICHLLGMRPRENAA
>T5BTY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomyces dermatitidis ATCC 26199|TrEMBL
MEKISDKIAALPRNANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRSLVDHALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTYAVDLVKYIRRTHGDHFCIGVAAYPEGHSDESHPEVQDPARDVPYL
VEKTRAGADFIMTQLTYDLEAYKRFENMLRTHESGVFKDIPIITGLMPIQSYHILTRTTK
LSHARVPPNIMARVEEVKSDDESVKRIGVDILCEIVNGLKEIPCPGPRGLHFYTLNLEKA
VAFTVERCSLIPPSSEPSSDSEADLDTAVSMVHGQLNNIVRMSKRRASSINSQPHNRLIV
DRPSDGRGSSQASTTHETQTLGAGMPALNPPHRATTLQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVTPAVARRLWGYPTTKEDINTIFQRHVSGDLHIVPWSEGGT
QDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAF
VEFFCTAHDLKTILKPIFENHGHDELAWFATNAAGDFESSSPPTDDSANDYSGPVDVYLD
SNATAGGTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRVFPRGSPTEK
LLDQLKNDVWLVCVVGQKYGAGCQSREAAETEGKLLWKLLAGQATEADSTNKH
>A0A7C2VU17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MARPFRQTLQEKDFIVTAEVGPQKGTDTRKVIENIELLKDKVDALNVTDNQGSVMKYPSV
GVCLLIKEHGGEPILQMTCRDRNRLALQADLLFAYSRGIDNVLCLTGDSIDIGDHNEAKP
VFDLDSVQLIHMVHTLNSGRDMVGNELEGKTDFCIGTTGTPSADPIEPQLIKFK
>A0A853BHP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomonospora nanhaiensis|TrEMBL
MLASSTRPGSAPTASARPRRIRELLKAGEPTFSFEFFPPKTPEGLRKLWRVIREIEALQP
SFVSVTYGAGGGTRDLTVEITERMATDTTLLPVAHMTAVNHSVRELRHLIGRFAAVGVGN
ILALRGDPPGDPLGEWVKHPEGLEYAEQLVRLLKESGDFCVGVAAFPYKHPRSRDVESDV
EYFVRKCRAGADYAITQMFFDADDYLRLRDRVAAKGCDVPIIPEIMPVVKPATIERSEQL
SGAPFPRHLAAEFEKVAHDPEAVRALGIEQARRMCERLLDEGAPGIHFITFNQSTATREI
YQQVAADRLPAAAAGRP
>A0A2B7JW05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium acnes|TrEMBL
MAPDFISVAYGANGSRCDRALRCTQHMVSTGLRTVGHLTCVAQSVADVEQMVADYAESRI
DHILAIRGDMLGGAGQPWVAHPWGLPNATELVRLVKWVHPEACIGREGA
>A0A7H8JAA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NA02536|TrEMBL
MALGTASTRTDRARTVRDILAAGKKTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVSHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PEALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A6N3H8R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium limosum|TrEMBL
MTIPEIMKNRMSFSFEVFPPKEGQPLEPLLDTLDHLYAFKPDFISCTYGAGGTNAGRNIE
ICKAIKDSGATIPITHFTCIGNSKDKIRDELRNYLSLGVDHILALRGDFPKGSASTGGDF
DYANELIAFIKEAFPEFSIAMAGDPEKHFEASSFDEDIAHLRIKQDTGADFIMTQLCHDV
AHYEWWVEKIRKAHITLPVDVGIMPVLAKDPTIRMAVSNGSSIPRDLAEIIARYGDNPED
FKKAGMEYTVKQIHRFISAGIDGLHIYSLNKWADISEIVRAAGIR
>A0A7L0TT35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chordeiles acutipennis|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEANGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVLAGADFIITQLFFHSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGVWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7R7HBZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L-8-10|TrEMBL
MNQFRFSRRPDIGGKIRVSFEFFPPKSDEMEARLWDTVTRLAPLNPHFVSVTYGAGGSTR
ERTIRTVRRILNETGLLPAAHLTCVDADQDAVDGVIGEFAAMGVKRFVALRGDPSEGVGA
AYRPYPGGYANGAELVAALKRVDDFDISVSAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFGQVANFSSRCGAHVPDWLAERFD
GLDKDPQTHALVAAAVAAEQVLDLVERGVTDFHFYTMNRADLAFAICHMIGIRGDLAVKR
AAPAAA
>A0A7X4JMF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MAITSRKNNFIDALTGQILVCDGAIGTELRKQVPAHLQCVDACNISTEHAEKVSMIHRAY
ANAGADIIQTNTYQANSEALAVHGLAEQAGEINRNGVRLARAAVPETCYVAGSVGPISFQ
TLDTTLPSTKAIRRIFKQQMDALVDEGVDLLVLETFVSPKQAEIAAKQALTYDVPVVVEI
SGVSGGTVGAGVDVRVFAQELEQLGAHAVGVNCRGPHDLVEAMELLAPVIKVPIAVQPNA
GNPRVEQGEVALSYTVEAEVFSDYVGKLIELGANMIGGCCGTTPAYVAKIRQAVTGRKPV
QRKQRIFVLPKIRSTSKVLTDNPVQQVFETREQIISVEMRANTFPQLRAMLREAKNLAAI
GVDLFDVTDNSGAAVNIGSVGTAYRLQQTTQIPTLIHWTTRSRNLISMQSHLLEAEALGI
RGIVALSGDHPKVGPYEAASLVPDVRGAVQLMKLIARLNHGELADGSSIGDPCGFYYGGG
FTVAENLQPHVKHLTNKVKQGAKFAYTQPVWTYEDIVRTQQATAHLGIKMLYGILPLTSF
RSASYLRDNLGLYIPQFIVDKFRNLEDTAAHELGIRLCLELIRDIRNQDECKIDGIYLIP
PARMNWKNRASVISEIVKTYR
>A0A848DNA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia bannensis|TrEMBL
MKDTSSGRGTVTERISVDRPVFSVEFFPPKDAAGEAELWRAIRRLEPLDPAFVSVTYGAG
GSSRDRTIRTTARIATDTTLVSMAHLTAVSHSVAELRRVIGAYAAAGIRNVLAVRGDPPG
DPLGEWVPHPEGLAYADELVRLIRRSGNFCVGVAAFPYGHPRSPDAESDLRRLVAKVRAG
ADFAISQLFLEPEGFLRLRDRMVEAGCDVPLLPGIMPLTTLRTLRRGPELSGAPLPADLV
KRLERFADDPVAFRAAGMEATAELCDKLLAEGVRGLHFYTLNRSTATVELVQRLGLAAR
>A0A2M9I8I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TSRI0384-2|TrEMBL
MALGTASTRTDHAPTVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSEDWDTDIRYFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LQDDKG
>A0A1I4VKI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium succinicans|TrEMBL
MKVTQHIENAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVN
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPTNGGNKYASDLVSQIYQLNQGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQTDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVERHLQVLPQIFRIDLPEDLIAAVEKCKNNAEIRQVGIEWAIQQSIELKTAGVPVLH
YYSMGKSENIRQIASQIF
>A0A2T3BBC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amorphotheca resinae ATCC 22711|TrEMBL
MHIKDMLAETERSGQPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVNVAQSQYGLETCMHLTCTDMGRDKVDEALKSAYRAGCTNILALRGDPPREKEK
WEATEGGFVYAKDLVKHIRQTYADHFDIGVAGYPEGCDDQDDQELLLDHLKEKVDAGASF
IVTQMFYDVDNFIQWVSKVRAKGITVPIIPGIMPINTYASFLRRCNHMGCKIPSSWSEAL
EEVKNDDAAVRNIGTGLVAEMCRKILAAGIRHLHFYTMNLSQATRMVLEELDLTPSSERP
LKQALPWRQSLGFGRREEDVRPIFWKNRNKSYVTRTQDWDEFPNGRWGDSRSPAFGELDT
YGIGLKGSNEQNQKLWGSPKSIKDISDIFVKYLEKGVDSLPWSEAPITSEADVIKADLIN
LNKRGLLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVSPKLMDELISRIEQDP
DLTYYAVNKAGNLKTNSGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDWA
HCHPSSSPTRNLIEHMMETWFLVNIVHNDFHQTNRLFSLFNSLEVEDLEKEFEGDLNGTP
QTN
>Q6FNS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)|TrEMBL
MSICKTFSDRDGPLISLEFFPPKTESGKRNLLERMERMSALDPLFITVTWGAGGSTSEKT
LELAQIAQRDLNVPICMHLTCTNMDTTLIKEALDACRSYGIKNILALRGDAPIEDQWDDK
TINSSEGPEFRYAVDLVRYIKENYGDEFCIGVAAYPEGHCEGEAEGNEQDPLKDLVFLKE
KIDAGAQFVITQLFYDVSKFLDFEKMFREQISETIPVFPGLMPINSFSLFHRAARLSHAS
IPKAVLDRFPQEIQNDDGIVKSIGVDVLIDIIEEIYSKTNGRVKCFHFYTLNLEKAVAQI
VSQSSTLSKILEESDNEEDQVVSQDEDGDIVLVDQHEENPLKFKRRRQSSSVSADVIFNR
AIINRGKTDRNESSELASKKLVVSISRGSGVLGRDATWDEFPNGRFGDSRSPAYGEIDGY
GPSLKVSNKRAYELWGSPTSIRDLKAVFVKYLEGSIQSLPWCDLGLSPETALIQEELIQL
NYRGYLTLASQPCTNASSSTDKIFGWGPSKGHVYQKAFIEMFVHRQQWKTILKPKLDYYG
RRKFSYYAGDSKGSFETNLDPHSSNVVTWGVFPNSQVIQTTIIEEESFKAWRDEAFSIWS
EWAKLFPRNTPSNTLLREVHSDYYLVSIVHHDFIETDELWDLLLD
>A0A2A2FUL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. WN033|TrEMBL
MSTHNKAPVSFEFFPTKTDAGHEKLIATAHVLAAHNPEFFSVTYGAGGSTRDRTLNTVLQ
LDGDVKVPTAPHLSCVGDSKDDLRSLLNQYRDAGIKRIVALRGDLPSGMGQASGELRYAN
ELVEFIRAETGDHFTIEVAAYPEAHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FHFVDRVRQAGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSDSIVA
FGTEVISDMCQRLLDGGAPGLHFYTLNQAEPSLAVWRNLNK
>A0A1I6KGV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella sp. OK004|TrEMBL
MPSISFEFFPPKTEEQRDQLDRAAKSLKSRKPDYVSVTFGAGGSTLSYTGETVARLHREH
GLDVAPHLSCMGGTRSEIADLLDSYRAAGYRRLVALRGDLPSGMASPGDFHYASELVSFI
RKHSGDHFHIEVAAYPETHPQADDALVDLRHFKAKVDAGANGAITQYFFNADAYFRFVDD
VRRLGVKVPIVPGIMPISNFSQLKRFSDACGAEIPRWIAKRMQAHGDDVESIRELAADVV
AQLCRRLLEGGAPGLHFYTLNRAKATQAILDRLHG
>A0A434U9Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1A.F.Ca.ET.072.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIREFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A653ZI54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. 8Y|TrEMBL
MKPIELSFEFFPPKTQEGVEKLRASRAQLAQLAPKFVSVTFGAGGSTQQGTLDTVLEMAA
EGLQAAPHLSCIGSSRESLRAILGAYREHGIRHIVALRGDLPSGMGEFGELRYASELVAF
IRQEHGDWFHIEVAAYPEFHPQARSPRADMENFARKVKAGANAAITQYFFNADAYFKFVG
EARKLGVDVPITPGIMPITNFSQLMRFSDMCGAEVPRWIARRLESYGDDRESIREFGLDV
VTGLCRRLIDEGAPGLHFYTLNGAAATKTICERLGFQSA
>A0A7X7QBI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MAEEQANGYKSGSNLEKILRAGRFAVTAELGPPQNADADVIRRKAQFLKGVADAVNLTDN
QTAIVRMSSIGSGLLAISAGLEPVVQMTCRDRNRLAMQSDLLAAYALGVRNLLCLTGDHQ
SFGNHPTAKNVHDLDSVQLIRMIKEMRDETRFQCGEAIKGASPRFFIGGASNPFGDPFEF
RPYRLAKKAAAGADFVQTQLIYDVPRFREFMKRVVDMGIHEQVYILAGVGPIKSAGAARY
MRDKVPGMIVQDEYVERMNAAVANIPKEDKAARRNAWMAEGIQICIEQIQEIREIEGVAG
VHIMAIEWEEAVRPIVEAAGLFPRPSVE
>A0A850AJ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MPGFTPGKRYQPPFMPFKRQPFKKRALATIELAVKGPLFGCRMCGNCLLQETALICPMEC
PKGLRNGPCGGSTPERCYVDESRPCIWYKIYERSFQLGREARLLEVLPPMDWEKAGTDSW
GGIFDRVKRLGIRNLFSHLTSGEPGSVSQTLDSIFRPVRQPDWWQGDAKYHAPAYAEPVS
ELERRLKAGEFVFAAEIAPPLSINTDKLRRNIAALKEHAAALNFTDNASSVPRMSSLACS
AISLELGAEPVMQISARDKTRVGLQSEVIGASALGIRNMLCLTGDSMALAPGPKGRMDIV
DIDSVQMLWMLRRMRDEGRYLDGREIKTPPKYFLGAAASPFASNMKFQALREQKKVNAGA
QFFQTNAVFDADALDEWLNELVKRDVLDKVYILIGISPLKSYRVARYMNDKVPGIFIPAA
VMKRMELAEEKGNAEEEGVQIALELIEKTRGKQGVNGIHLMAVGWEEVVPRIIEEAGAAK
SSKLRALKGGIPLGIIQPDE
>A0A7L6CQU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. RHBSTW-00994|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWDSGIRHIVALRGD
LPPGSGKPEMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLEDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A0K0QHB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIGAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2B0MMI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKILDLLSKGIIIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADIIQTN
TYGANEAKLRTYGLENQVVQINRAAVKLAKAAITDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALIEENVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQIALHEAGTTQNGN
DVNEILERLLDYGANVVGLNCQLGPLHMTEAFKMISIPRNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPAHVEAMKRAIANVTPVTEKQIVQRKQVVP
MQTKRISTHITLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNEGRSILGKSIGSATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMDGHGTQESAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITENLVKYVK
EKQEVKEGVN
>A0A3N5A844|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ag109_G2-6|TrEMBL
MALGTASTWSDRAHTVRDLLASGASYSFEFWAPKTEKGERNLWNALRRIEAVSPSFVSVT
YGAGGSTRGGTVRATQQIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMGPWVKHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSDNWDTDIRYFVDK
CRAGADYAITQMFFDPENYLRLRDSVQKAGCETPIIPEVMPVVGIKQLDRLPQLSNAVFP
DAVKDRMHAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>I3KND8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oreochromis niloticus|TrEMBL
SVNQSSTMSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMESGDRWFSLEF
FPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLES
ILHLTCCNQSKEKITGYLAKAKHLGLKNIMALRGDPVGEDWEEEEDGFNYAIDLVKHIRS
EFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFLKFLDDCR
AIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNYGIQQAVE
MCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRP
IFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLQMWGEE
LQNEESVFEVFTSYITAQPNHCGHKVMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINS
QPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVN
GRNLTNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWGKLYEDESP
SRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPELHSEETV
>A0A5J6JEF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces vinaceus|TrEMBL
MSARPTPYPERPAQAPVTGGGLAELLRRVRYEVLPAKATEDKVLAHVPAEVPVTVTASPA
KGIGPTLDLATRLAGHGYRVVPHIPARQIADAGHLSDIVDRLVAAGIEDVFVPAGDADPP
AGAYDAALPVLRRLGELGSPFAHVGITGYPESHPLIADEVAVRAMSDKQPHATYIVSNLC
FDPATLRQWLGQVRRRRIVLPVHVGVAGPVERAKLLSMATKIGVGESAKFLTRHPSWFLR
FAAPGGYSPDRLLRRAAPVLGAPESAVAGLHLFTFNQIAETERWRRAMLERTGG
>A0A0Q5DAH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Leaf306|TrEMBL
MDTPAAKAPFKLSYEFFPPKSDEMQTQLWETVDALAAFKPEFVTMTYGAGGSTREPTLAA
VQRMINDAKLQTAAHLTCVDAAREEVKSVVEEYRAAGVRRIVALRGDSSAGVGAAYTPHP
DGFSDTADLVRMLVEYGDMDISVSAYPEMHPESPSMAADIDTLKRKADAGANRALTQFFF
DNEVFERYLEAVHAAGITIPIVPGIMPIQNLTQLKRFAGRCGATVPAFLDARFEGLDDKP
DDRAKVAADVAAEQIADLMRRGHDHFHLYTMNRVPLVSGVLERLGRHPDKDANVGNAA
>A0A366ZRG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. TF02-9|TrEMBL
MTVTQTVRELLASERPTWSFEFFPPKTPEGEQQLWSALRELERLQPSFVSVTYGAGGSTR
EGTVSVTERIATETTMTPLAHLTAVDHSIAELRHVVSRLAAAGVRNIIALRGDPPGADPQ
AEWVAHPEGLSYAAELVALIKSMGDFSVGVAAFPERHPRSPDFDSDADMFVAKCRAGADF
AITQMFFRADDYLRMRDRVTERGCDVPIIAGVMPVTNARQIKRIVQLSGQAFPAELAERF
EALDGDRPEDKAAVRAYGVEVATELCRTLLDEGVPGIHFITMNRSTATREVHANLVGTPS
VTTAG
>A0A1G9S1T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzisolibacter propanilivorax|TrEMBL
MSAVATPLPVSFEFFPPKTPEGAEKLRAVRQQLYARAPQFCSVTYGAGGSTQEGTFTAVR
EILAEGVQAASHFSCIGATRESVRAQLAELKGMGVKRLVALRGDLPSGYGAGGEFHYASD
LVAFIRAETGRDFHIEVAAYPEVHPQARSADADLQAFATKVRAGADSAITQYFFNADAYA
RFVEDTRRLGLDVPVVPGIMPILGATQLMRFSDACGAEIPRWIRLRLQGYGDDVASIRAF
GLDVVARLCQQLVAAGAPGLHFYTMNQSAPTLALCDRLGL
>A0A3P9NVP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poecilia reticulata|TrEMBL
MVNQVQQVDGSWQSCRGDSSGGSNSSAESSNESSRCSTPVLDADRSDRLREKMRKRTESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGDDWENEEGGFNFAV
DLVKHIRSEFDEYFDICVAGYPTGHPEAESYEQDLQHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAAGITCPILPGIFPIQGYQSLRQLVKLSKLQVPEEITKIIEPIKDNDAAIRN
YGIHQAVDMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWVEDPRRPLPWAVSANPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKNEQSVFEVFTCYITAQPNRNGQKVLCLPWNDEPLAPETNFLKDELEKVNR
XGVLTINSQPNINGKPSADPVVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGHNMTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKVRYQACSFRSLW
>A0A7C4WN36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSPRDPSARAVPKLFSFLFRLVSQVVPLAVRLSGPRLSRQGRDRPGEDRSGERSGGRMRF
ADVVSQKSFSLVMQVDPPKGTGAESLMDSILAVRGRIDAVAFTDNPMAIMKMHPLAPCHL
LRRKNVEAILGVNSRDRNRLSLQSELLAAWALDVRSVLFREGEDPTYGDHPLAAPCRDLT
LESMLEAAARFRKGTDLSGQPLDGPVSFHVGVSIPITDDRDANRARAEGLGRWASLGAQY
AVLDPTYEIGTVEAFSRSASQAGLKLFASVLLLKSVGMAKYLNSVPGVPDIPDEIIQRIQ
KAPVKPKACLEIAAEFIRRLGETCDGVFVVPLGWESRVPELLDLLSD
>A0A7C3G5J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAKSLFEEKLNSDEFVITTEIGPPKGVDLTEMIHHIDLLKDKVDAINVTDHQSSVMRYPS
LGGCLLVKEHGGEPIFQMTCRDRNRLALQADLMFAYSRNVVNVLCLTGDSVDVGDHKEAK
PVFDADSVQLLEIIKTLESGYDTAGNELKGVPQFFAGASVHPEADFIEPQLVKFDKKVSS
GARFFQTQGIFDLASFRRFMQYASQFEVKILAGIIVLSSAGAARYMNKNVPGILVTQEII
DELASVEKGKGLEKGMEIAARFIRTIREEKLCDGVHIMAVGNEQIVPEIIAASSTVSIPS
>A0A7C1WPB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKDKSPAQPLLSTTLDTHKICYFQSKLKTSLLNKGEFTLTFELVPGRGSRGKVHDALLAF
AEKASAGGKIQALSLTENAGGHPALSPEVLGREIKNLGMETIVHFSCKDKNRNQIESLLF
AWDREEIHNLLILTGDYPRYGYEGPAKPVFDLDSVTLLSMVSQMKSGYYIHSQAPGGGRF
LPSMPFFKGCVVSPFKRLESELMNQYFKLQRKAAAGADFVITQVGFDVRQFDALLRYMRL
NEINLPILGNVYIPSITVARLMHEGKVPGCVVTDELMALYERESGEPDGGKEKRLLRAAK
LLAVQRGLGYDGAHIGGSKLTYDDVEFIIGKSENLYRNWPDYISEFSFPQKDGFYYFEKD
EQTGLNRDVPAKPESTSGHRATNYIFSRSIHNLVFDENGVLFRPAKNFCRAIAGTKWARP
FARFEYLPKQFLYECKKCGDCVLSEAAFLCPESQCAKYMRNGPCGGSIDGWCEVYPGVKK
CIYVRAYERLRSYGQKKRLKEKIIPPRDWSLNNTSSWINFFTGRDYAGKIKSRKR
>A0A4Q6D940|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSLFSNGILIFDGAMGTELYDRGFYINRPFEELNLSSPQDVESVHRNYIDAGADVITTNT
FSIAGPQLKKFDVEAQQGSLIRAALDCAHRARVGTKVQIALSVGPTGELVEPLGPTSISE
TRETFQRIAVHAVEDGRFELYSLETFSNLRELEAAIDGIRAIDSHRPLIASLSLHSTQQE
LLDDFAATVGARTDVDALGLNCAVGPSDLLTSLKRLRALTTKPIICQPNAGSPRHVNGRY
FYMTSPDYLGKYAKRFAEAGASGIGGCCGTGPDHIRAVRSAVRMQNSQLVSPSSLKFEVK
SAEAKGQARRTLSERIESDVSRKLATGQKIFSIEVLPPKGTDLKKFLSSIDLMMGKNISF
VNIPDGARASSRMGSLHLASLLKHNYGENLSVIPHFTTRDRNLIALQSDLIGAYVNGVRD
VLLVTGDPPKLGNNKEATAVYDIDAIGLAYLVDCLNRGVSPIGESLGLGTSYGIGVACNP
TAINPEVEFSRWKYKV
>A0A7V2P7V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MEEGLQIEADEYITLSAEDGRASASKLAEPIARLRERLSTRLKERENIVKAAILDPDTFC
ITWEQIPGRGAFEMQQEDLIENARRAARSGKIHAVSVTDNPGGNPAISTEMLCTEVKKLG
IEPLVHLAFRDKSRNQCESLLYGLAGLDVRNLLLLTGDYPGNTGFRGMSRPVFDLDSVHG
LQLVETMNQGIEQALPSGKTTTLAPTDFFAGTSVSPFKQTEAELMGQYYKLQKKIEAGAK
FIITQVGYDARKLHELLTWLKVNGHRVPVLGNIYILTYGTARLMNANGIPGCVVTDKLVA
ELDNERKSEDKGRSARLTRAAKMYAMFKGMGCAGVHIGGHGITYSQVEHIIDEGEELTPN
WRDIVAEFDYPQDNGFYYFEKNPADNLNLEKPSAKTEKPKRPLIAIFARIAHTLLFEPKS
PIFKMLLPFARFVDRSRARRHAFLYLEHLAKVVLFNCQNCGDCALFDVGYLCPMSQCPKN
QRNGPCGGSYQGWCEVYPNEKKCVWVRAYLRLKSYHEEESIAENLVPPCNWEFWETSSWL
NFYLGRDHSAVKMGIKPPQDKKSGDS
>A0A839Q6M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium iranicum|TrEMBL
MAMSVGEELLAVQDCPKRMHNGPCGGVRPDGQCEMRTGPCAFPSVVEWSGAVAEPRAVSA
PLILTDFSCAPFDPADLAATATALSASCDAVLVGEHQNRPDFPPALMAPMLLDGGVVPWI
TLSCRDRNRVVLEQELRGLQHLGVQTVLCVTGDGRAYDVRPDVTQTFDLDGPRLASFASS
LGVTAAVPETPTAPPVTERPRRLVEKQRAGAGIAVLNHVSTPGLVADFMAAAIGAGLSIP
VLAAVAVLTDEVSAAVLQGLPGLALDTAVVESILSAPDPREAGIAAAVAEARALLAIDGV
AGVNISGLASGSGTRVGAQIKAEVGQRIREEVGMND
>A6T2Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. (strain Marseille)|TrEMBL
MKDQNFSIEFFPPKTPAGVEKLRVTCAKLAELNPKYFSVTFGAGGSTQQGTLETVLEIRG
AGQDAAPHLSCLGSSRDSLRAILAEYKSHGIKRIVALRGDLPSGYGAMDMSSSEFHHANE
LVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDIASFVRKAKAGADSAITQYFYNADAYF
RFVDDARKAGTDIPVTAGIMPITNYSQLMRFSDMCGAEIPRWIRLKLASFGDDSESIRAF
GLDVVTDLCERLLAGGAPGLHFYTLNQAVATHTIWTRLNLSQK
>A0A7I0KAX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M8A.F.Ca.ET.167.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHEVDAVIREFTDMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVA
GSAAA
>A0A523UVK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSIVELIKQGKFVVTAEVGPPKGVDIQEMLETAEVMRGRVDAINATDQQSSAMRLGSLAT
CCILKQKGLEPVFQVTCRDRNRIALQSDLLSASVLGIENVLCLTGDHVSLGDHPQAKPVF
DLDSVSLLQAAKELEQGKDLAGKELEGSPKFCLGAVVSPASEPVEPQIIKMEKKVKAGAE
FIQTQAVYEPKKFEEFIKATAHLKVPVMVGIVLLKSAGMARFMNKNVAGVNVPDNLVEEM
DEAEDRAKKSIEIAARLIKEMKSMCQGVHIMAIGWERKVPEVLDAAGL
>A0A7L9MN82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella suis bv. 5|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRHAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A431I7G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MFVTKHLEDATKPLFSYEIVPPLRGSSSIGNVFSIIEQLLPYDPKWINVTTHASSLLYVE
KGDGSLVRRIHKKRPGTIGICGAIQNKYGIDAVAHVLCQGFSQQETEDALIELNYLGIDN
ILALKGDNLNYNRVIAEYESVNKHAVDLVGQVALMKQGKFLGNTEYSPMHFCTGVAAYPE
KHFEAANMELNLEYLKQKIAAGADYIVTQMFFDNQKFFAFVKACRDAGITVPIIPGIKVI
KSVAQINSLPRLFHIDLPHELVTRLLTNPDNAVNIGKEWAMQQVGELLDFGVPCVHFFLM
NDVDNVLDIIRNYNNK
>A0A3C0Z301|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIRQILESKRTLSFEFFPPADDAGVKRLFNTIYALKAYDPDFVSITYGAGGSTQAVTVE
MAVRAQRETGLTVMAHITCAAQTAEFVDSALSRLATEGIENLIALRGDPPKGKSKFTAVE
GGYTHASDLISHVKRKFQFGVAAAGYPEGHPESIDLESDMKFTRLKIDLGAEFLITQLFY
DNDDYYAFVDRAQKAGVNVPIIPGLMPVLSASQIRRITGMCGASIPKELDELLDRHGDDN
RAVRQIGIEHTTRQASDLLDSGVPGVHFYVLNRRFSMTRILENLRESGHTTAFS
>A0A523S4K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKSKSKLEKIMESGHFAVTGELGPPASADAEIIKKKAKYLKGCVDAVNVTDGQTAVARMA
SWAACLLGKAEGLEPTVQMTCRDRNRIALQMDILGVAALGINNILCLTGDHQSFGNHPMA
KGVYDLDSIQLIKMVKDMRDEKKFQCGDEIAVEPRLFIGAAANPFADPFEYRVSRLAKKA
AAGADFIQTQIIYNVEKFAKWMEAVREKGLHEKVKILAGVAPIKSVGAARYMQTRIPGMD
VPDAVVERLRGVPKEEVSREGIKLCVDIINQVREIKGVAGIHLMAIEWEEIVPEIVERVG
LLPRPQVS
>A0A120GAQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. YT30|TrEMBL
MSPTLDQLHEAKTAVGAPLFSDLPGDIDISFEFFPPKTEKMAETLWDSVATLSPLGPRFV
SVTYGAGGSTRERTHQQVVRIQNEAKIPAAAHLTCVNATKEEVNEVARHYWEEGIRHIVA
LRGDPPEGASGYSPHPGGYENAADLIAGLKEVADFEISVGAYPEVHPDSPDAQSDIANLK
AKFDAGADRAITQFFFDPECFFRFRDEVAAAGIDAEIVPGIMPVMSFKAVQRMSNMCGTE
IPSWMEGLFEGLDERPAARQLVSATIAAELCRKLYAGGERKFHFYTLNRAELSYAICHML
GKRPVGEAA
>A0A3N8BWP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Bp9125|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDREAIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATRTICERLGA
>C5CM27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax paradoxus (strain S110)|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPEFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
SRKLGLGLPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLQGGGAPALHFYTMNQSAATLAVLERLG
>A0A1V3JRA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter myodis|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMENMLWDSIHRLKVLEPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLVAAPHLTGIDASPEELKQIAQDYWNNGIRHIVALRGDEP
KGYEKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIEAEIVPGILPVTNFKQLQKMASFTNVKIPAWLGKAYEGL
DDDPATRNLVAASVAMDMVKILSSEGVTDFHFYTLNRSELTYAICHMLGVRPKI
>A0A523VNG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKTRSNLERVLESRQFAVTGELGPPPSADAEVIRKKAKILKGHVDAFNITDGQTAVVRMA
SWAAAVMGKEEGLEPIVQMTCRDRNRIALQMDVLGIAALGINNMLCLTGDHQKFGNHPAA
RGVYDLDSIQLVRMVKDMRDEKKFQCGDEMAVEPRLFIGAAANPFADPFEFRVTRLAKKV
EAGADFIQTQIIYNVDKFAEWMKGVRDRGLHERVKILAGVAPIKSVGAARYMKTRVPGMD
VPDSVIERLQGVTRERVSGEGIQLCVDIINQVRQIEGVAGIHLMAIEWEEVVPEIVEAAG
LLPRPRFTP
>L0KPH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium australicum (strain HAMBI 3006 / LMG 24608 / WSM2073)|TrEMBL
MTGRQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHDDITETQVDMVK
TAH
>A0A2W4MMI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSHAPFRPSRRGACPVRVSFEFFPPKTPEMEETLWASIKRLAPLGPHFVSVTYGAGGSTR
ERTHATVKRLVEETSLAPAAHLTCVSATREEVNEVVRAYWEAGVRHIVALRGDPAEGIGA
AFRPHPGGYEGSPELVAGIRAIADFEVSVSAYPEKHPESVSI
>A0A2E8UWZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKEISDATAKRIKEDLEKSYMEIIPVPGIEDKVDPLPSDMYLAVTCSPTKGVDETLDLSE
KLIGKGFKVTPHIASKCVSGEKHLEVIIKKLDQLGIESIFVPGGDRPEPMGDFKNASDLL
RALKKLGHNLNKIGMAAHPEGHPDVSDEILMEALDEKKDLADFIVTQMCFDAEILNDWMT
QIHKKGIRLPVWVGLPGVIERGRLLKTSLRIGVGDSLRFLRKKSQVATELMKSSIYNPND
LLRDITEQNDINTSNLAGYHIYCFNQIETTEKWRTDTISSLN
>A0A2U3XVU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptonychotes weddellii|TrEMBL
MDHPTPKVLPARPHSPSLGMWALEAGRVRFSVPPSISRNPAMVNEPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQEQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRREFGDYFDICVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDDAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFACYLS
GEPNQHGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPTPEQGAEAL
>A0A822GC74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood1|TrEMBL
PPVGEKWDPEKTDFRYASDLVKFIRENFGDYFVICVAGYPKGHPDSKTYEEDLHYLKEKI
NCGADFIITQLFFQAETFLKFQSDCQAVGITCPIIPGIFPIQ
>A0A7V1RDG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthonomonadales bacterium|TrEMBL
MRIAECFLDGRPVFSFEFFPPKSPEATERLYRTVARLARLEPSFVSVTYGAGGSTRRLTV
ELVARIKEEIGVEAMAHLTCVGHRAEEIAAILADLRGHRIENVLALRGDPPQGATEFVRP
EGGFSHALELVAFIRSRFDFCVGAAAYPEGHVEAPDRETDLRRLKEKVDAGVDFLITQLF
FDPADYFRFVADARSLGIRVPILPGIIPVTNVAQIERFTRMCGARIPTELQERLDRVRDD
DEAVVREGIAWATAQSRALLEGGAPGIHFYTLNRSRSSRAVYQNLTGRAAR
>A0A2W7N513|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacillus insolitus|TrEMBL
MGLLEELKTRMLTADGAMGTLLYSYGIDYCNEELNLQKPEIIEKIHQDYIAAGADIIQTN
TYGANAIKLERYGLENQIKEINEAAIQIAKRAAAPGGQFVLGTIGGIRGIRKSDATIEDI
VRMVDQQANHLLTGNPDGLLLETYYDFEELSATVKYLRSITNTPIIAQVSMHEPGILQNG
LALNDALHQLEALGADIVGVNCRLGPHHTIQAFEEVTLPKKAFLSAFPNASLLDVEDGRI
VYESEADYFGRAALLLREEGVRLIGGCCGTTPKHIEAVKKYIGNLAPITNKVVTPRKPIV
IRDAEPPKSQPIHEKVKTERTIIVELDTPRHLDITTFIEGSKALHATGIDAITMADNSLA
SPRISNLAMGSMLKLEHKIRPLTHITCRDRNLIGLQSHLMGLDALGMHDILAITGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVQR
LEKKIESGADYFITQPVFTKEKIQEIYEATKHLSTPIFIGVMPLTSIRSSEFLHNEVPGI
KLSEDALERMRACGEDKDRATAEGIQIAKELIDTAAELFNGIYIITPFLRYDTSLELIKY
IQEIDAKKERDHTYVQTSN
>A0A543AGT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enteractinococcus coprophilus|TrEMBL
MDFTTPSFETTVRQVGQFVDVADRMPGDAPINVAFVEEISVAQRLAAIRTLSAAGLRVRP
ILSARRLASEAQLGELLETSCGKLGLQEVMIVGGDPTEPAGPYATALKLIQSAPITEADL
RLIALPGFPKEHPTTSSAVLLDHLAAKVDALEATERAVEITTQLCLDPAAVQEWVTKVRA
RGITAPIRIGVPAPTTAAKLLRFCALCKVDATQEDLQRYGWLADHDATLVDPGAFLRSLT
RMLTSELGPIMAHIYPMGDIGAALTWLSSRQVELMQG
>A0A4V1J8P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrotalea sp. AMD|TrEMBL
MKVIEHIQQAKSTLLSFEVLPPLKGKTITSLYDHLDPLMEFKPSWINVTYHRSESMFKKK
ADGSFEKVEVRKRPGTVGICAAIMNHYKIDTVPHLICGGFTKRESEDALIDLNFLGIDNV
LVLRGDAAKNETSFEPEPDGHAHAIDLQKQVVNLNHGIYIDEDIRDGGKTNFCIGTAGYP
EKHFEAPNLDTDLQFLKEKVEAGADYIMTQMFFDNKKFFAFVKACRAMGIQVPIIPGLKP
ITSKKQLTVLPRIFHVDIPTDLSNTILNCKTDAEVEAIGTTWLIQQSKELKAAGVPVLHY
YTLGKPKVIRNVVKEVF
>A9MI20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5C4U2Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium tapiri|TrEMBL
MCAYAPAAGRISASAPVNSFEQATPEHHAWDRIALSFEVIPPRYGVEADVAKLDALLAEV
EAYRPDYIAVTSSQRSGWLEGTTALIRYITETTRLRPLAHVACTTGPATEMVRGINELVD
AGVRGILALRGDLPVGETSLPAGYLQHATDLIRVIRDVEKRQAARFAAGSVAVGVACYPS
GHAESRSEDEDFDVLLAKQRLGADFAITQLFFEAEDYLNFVRKARLAGVTIPLIPGIMPM
TSVSRLMRMGKLAGVKVPEHIIEELSVAAKFGPDVELETGLELSSRLAREVLAGGAGGLH
VYTHNDAVVTKELLERSGVRPSRPIEAPSPFRHSA
>A0A4R6QSA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium sp. AG952|TrEMBL
MADRAGTSATSGPGGSPPPNPASRQAQFEVIPLPGIAERALEHLPAGSRVTVTASPAQGL
EATLEAATALAAGGMVAVPHLAARMVEGPDALERILERLGGAGIEELFVIAGDATPPAGP
YDGALTLLEAIAPAGRGLVVGVGAHPEGHPHADPAAALELLRRKAEHASYVATQMLFSPD
PLLTWAEQLREAGIDMAVRPGVAAPASRTRLLRIGTRIGVGRSLRMLTAESSGVRRLLGP
GHWDPDPLLDALAAAELPGLAAPHVFTFNSLAETAAWWQARIGRA
>K0TBA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassiosira oceanica|TrEMBL
MVRIIDKIIARREEYAWERDHQPPNDDVGGDQRHDPSKIEPPGWDGDCDEAQQQDPNKDI
KPGWYYSFEFFPPKTEAGLDNLLTRIDRMSRRLDPLFVSVTWGACGSTLSRTLAVASHAQ
RFACVDVLLHLSCTGLSRERIAQVLNMAKSSGIRNILALRGDSPHGTWKEGDVSGGECDR
AIDLVKLIRQLHGDYFSIGVAGHPEGHASSPKGDSGGDVEMQHLKAKMLAGADFVMTQFF
YDMDVFLDFVRRCKKAGIDSPIIAGVMPVQSYSSLIKMTEFCGISVPQSLLDRLEGVKDD
DEEVKTIGWEHATEMCRAILTSAESEDFQVEGFHFYTLNLERSTTRILAALGAVEVLDGS
SRASSSTMLDQNQDQGRQRKESISERATSTRRVLPWKPSAMDRRLKEDVRPINWSNRPRS
YVQRTDDWDDYPNGRWGDSTSPAFGELSELSHFYSFTLGSDDDRRAMLGTCPLKETDVYE
VFARYVEGKVPHIPWCETPLQPESFLVQSQLARLNRLGLLTVNSQPNVDGASSSHPAFGW
GGKGGRVYQKAYVECFASPEKTNKLTRMVTDHASLNLYAVNKSGQELRVGVETGGVTALT
WGAFPNREILQPTIFDPETFLVWAEEAFSLWSSMWLNLYDFESQSYSLVESIRDNYFLVA
IIDNDFTKMPEEDSTFRLLRLLLEIGND
>A0A0U1NJJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nereida ignava|TrEMBL
MPSASVSFEFFPPKSIPAAFRLWDCVQTLAPLDPSFVSVTYGAGGTTRKLTHEAVSALSS
QTDLTVAAHLTCVDQTRDETLEIARAYIDQGVRQIVALRGDAPKGQAQFTPHPEGFASSL
ELISALKAEGVEHIRVGAYPDCHPDATDMKANVDWLKRKIDAGADSALTQFFFEADTFLR
FRDHCAAAGITAPIIPGILPIETWSGVRAFANACGTPTPRWLDDAFDKATRDNRADLLAI
SLATELCDTLITEGVEQLHFYTLNKPEMTRDVCHALGITPQLELEKVA
>A0A8G1TGM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. AF13-16|TrEMBL
MKLSEAMKNKMLLSFELFPPKTDKGMENLPGTIEHLCKYQPEYISCTYGAGGTNVGKNMD
VCKMIKDAGTIPVTHFTCIGNTAEGIKEQLQNYLDNGVDHMLALRGDLPFGWTGTGGDFA
YATDLVAYVRKEFGDKIEIAVAGSPEGHIACRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKRWLDAIRTAGVTMPVDVGIMPILDQAATINMALSRNGCVMPRKLCEIISKNWIFPN
PFDKDPFDAAVDEKKAAFKEAGIEYTIRQIDEYRALGVNGIHLYALNKWKDVSEIIDRCG
LRTLV
>A0A0H2ZP69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)|TrEMBL
MSRQTPSLSFEVFPPTPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIELIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDIAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A7U4Q4J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea vagans|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRIGLEAAPHLTCVDATHDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMSAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAAA
>A0A1W1I4M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira japonica|TrEMBL
MTREPSRLKDVLDRKQFAVTVEYNPPKGTNVTGLLDNARQLVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHLLGIRNVLCLTGDYPTVGDHKD
AKPVYDLDSVQVMQLVQGLNDGRDMAGNKLDGATAFQIGAAVTPEADPLGPMLAKFEVKV
KAGAGFFQTQAIYNPEQFASFMTAVRPFKVKVLAGILVLRNAKMAEFMNAHIPGVSVPQA
MIDELRAAGDKSEDAGVEIAVRTIAAVRPHCDGVHIMAIKATHRLGEILTKSGIG
>A0A2W6RS35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp|TrEMBL
MSSQQSHPSIVQRLAEPHPGPVPFSVEFYPPRDEQAEARLWRTVRIFERMGPAFVSMTYG
AGGSTRDRTLRITGQLARETTLLPVAHLTAVGHSVAELRAMIGGYADKGITNILALRGDP
PGDPLGEWVKHPEGVEYAEQLVRLVQELGDFNVGVASFPEGHHRAPDLDHDTKYLVSKLR
AGAQYSITQMFFDVDDFLRLRDRVAAMDPEQGAKPLIPGIMPITSLASVRRMVELSGSVL
PEAVDRRLAAAAGDGSEENREAVRAVGIDLATEMAQRLIDEGVPCLHFCSLNFAKATSEV
LERLGMNVMAA
>A0A1H0MDB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klenkia soli|TrEMBL
MTGTVRDLLDQARPTWSFEFFPPKNEAGQAQLWTALRELERLNPSFVSVTYGAGGSTREG
TLAVTERIATDTTMLPLAHLTAVDHSVAELRNVVSRLAAAGVRNIMALRGDPPGADPQAE
WVAHPQGLRYAAELVELVKGIGDFGVGVAAFPESHPRSPDPETDADMFVAKCRAGADFAI
TQMFFRVEDYLRLRDRVAARGCDVPVLAGVMPVTSAKQIARIVQLSGQAFPAELAERFEA
VADEPAAVQRALGVDVATDLCAQLLAEGVPGIHFITMNRSTATREVYSRLAPVNAVAAS
>A0A5D9CKI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas eurihalina|TrEMBL
MKFDDEPVPGYSLPVLPGHVSPGRLERVLRAGRFAVTTEIDPPDSADPAEVLRRAAIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYATILQMSCRDRNRIAMQGEILGAAAMGAC
NLLCLTGDGVQAGDHPHARPVFDLDSLSLLGIARRMRDESCFESGRPIDSPPRMFLGAAA
NPFVPPRAWRAQRLAKKVAAGARFIQTQYCFDTAVLRDFMAEIADFGLLEGPDRIHVLVG
MGPLRSARSARWIRDNVPGIHIPDRVIERLEGAQDQREEGARLCRDILQEVREIEGVSGA
HIMAYRQEATVARIIEETGVLEGRVPWYPGRDNPAELNPEAPEAAGDLPATASS
>A0A2E1G4M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp|TrEMBL
MTSTAHPAPSIVDRLSAPHRGPVPFSVEFFPPRDAEAEARLWRAVRAFERLGPAFVSMTY
GAGGSTRDRTARIAGELATETTLLPVAHLTAVNHSVDELRALVGSYADNGITNILALRGD
PPGDPLGEWVRHPAGVEYAEELVRLIADLGDFHVGVASFPEGHHRAPDLDHDTRTLVNKL
RAGAEYSITQMFFDVEDFLRLRDRVNRADPEQGAKPLIPGIMPITSLASVRRMAELSGSV
IPADVQERFAAAAGDGAEENREAVRAVGIDFATEMAQRLVAEGVPCLHFCSLNFAKATSE
VLERLGVDTSSALPAASH
>A0A379IN48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mendocina|TrEMBL
MSNPCSSFIPYTLEVTGKGIHEVEQARAVIPAGTPINIAFLGNEDHAQRIHAAKVIRACG
AEPVPIISSRRLRSEEDRDELIGALVSQAAPKRFMFVGGDPATPAGPYQDSLALLASGVL
ERHGIDQVVITGYPEGHPKIDSGELMRALKWKLDFLREAGCAVEITTQFGFDAEAVVRWI
EQLRQQGIDTPVRIGVPGPADVGKLLRFARQFGVATSAAILRRYGLSMANLMQRVGAERY
WDQLQAGLGGRQLGRIGWHLYPFGGVEDGVTWINARLSADSRPQALPG
>A0A640T3A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces glebosus|TrEMBL
MRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALRGDPPGDPMGEWVRHP
DGVGYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVTKCRAGADFAITQMFF
YPEDYFRLRDRVTAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVRDDP
AAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQQS
>A0A2E7GRP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium|TrEMBL
MVSYAQGIDALNQSLSEVKGINVSFEFFPPKTETMEKTLWKSVERLAPLKPKYMSVTYGA
NSGERDRTHEIVKRIQSETGIAAAPHLTCVDASREELKQIAKDYWASGIRKIVALRGDLP
EGYTEHVSYASDLVALLRDVADFDIAVAAYPEKHPEAPNSQFDLLNLKRKAEAGANQAIS
QFFFDAEVFLRFRDRAAAAGIDMDIVPGILPVTNYQTLQRFAGFTNVHVPNWLHKMYDGI
DKDDQTTRNLMGASIAMDMVKVLAKEGIRDFHFYTLNRCELSYAICHMLGVRAD
>A0A3M1RVM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Schekmanbacteria bacterium|TrEMBL
MKLTELFEKNTFVKTVELEPPKGTDTKIFLEKADSLKESVQFFNVTDQQSAVMRAGSLIG
CSILKEKNLEPILQISCRDRNRIALQSDLLNAAILGIENVLVITGDHPYLGDHPDAKAVF
DLDSVQLLQAIERLNNGEDMAGNKLEGNFSLCCGAVFTPSADNPELELIKIEKKIKAGAK
FFQTQAIFDVESFNSIMNSVKDFNIPVMAGILILKSEKMANFMNRQIAGIKVPEEIIKRM
EKAEDKRKEAVDIAVSIIDEVKDKCQGIHIMGLGWEDLIPEIIQKSSL
>I9PM27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides caccae CL03T12C61|TrEMBL
MKVIDLINNSKKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEEAPNIESDLYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAERVGIEWCVTQCKELMSHGAPSIHF
YSIGAVDSIKEVAKIIY
>A0A1R3J140|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corchorus olitorius|TrEMBL
MKVIDKIKSLQGGEGENGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAG
GSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPH
GQDKFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDAIGSDGVATPEAYQNDL
EYLKRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGF
CKTKIPAEVTAALEPIKDNEEAVKSYGIHLGTEMCRKILAHGIKTVHLYTLNMEKSALAI
LMNLGLIEESKISRNLPWRRPANIFRVKEDVRPIFWANRPKSYITRTLGWDQYPHGRWGD
SRNPSYGALSDYQFMRPRARDKKLQEEWATPLKSVDDIQEPETKIIHEQLGKINLKGFLT
INSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCPKEKLDALVDKCKGLSYITYIAVN
KTGNLLSNIGVADVNAVTWGVFPAKEVIQPTVVDPASFMVWKDEAFEIWSRTWAALYPDG
DPSKKLLEEVQSNYYLVSLVDNDYVGGDIFAAFEDL
>A0A4R2NAT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nicoletella semolina|TrEMBL
MSYAREIDLLNQNVADLNGKVNVSFEFFPPKNEKMESLLWESIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKSIQQETGIVAAPHLTGIDATPDELRVIAKDYWESGIRHIVALRGDEP
AGYTKKSFYASDLVALLKDVADFDISVAAYPEVHPEAKSAQSDLLYLKQKIDAGANRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMSKITNVKIPSWMQKMYQGL
DDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRAELSYAICHTLGIRP
>B4S8Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecochloris aestuarii (strain DSM 271 / SK 413)|TrEMBL
MLVKEILSSTDNPIFSFEFFPPKKNDDWDRLFRTISELIPFNPSYVSVTYGAGGSTRTRT
HDLVTKIRKETGLTVVSHLTCICSTKDEISDILSTYENNGITNVLALRGDLPPGTTSYSE
ATKDFPHAIDLVRFIKTNFPSFGIGVAGFPEGHPQTPNRLDEITYLKEKVDAGADYIVTQ
LFFDNRDYFDFVDRCALEGITVPIIPGIMPVTTKKGLIRMSELALGARIPAELLKEVIEA
PDDQSVAEAGIRWATKQVRELIDHHIKGIHFYTLNHAEATRMIFNNIPEAKSKEQA
>X0CIP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. raphani 54005|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A0F4J7H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces katrae|TrEMBL
MALGTASTWSDRAHTVRDLLASGASYSFEFWAPRTEKGERNLWNALRRIEAVSPSFVSVT
YGAGGSTRGGTVRATQQIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGNPMGPWVKHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVDK
CRAGADYAITQMFFDPEHYLQLRDRVQKAGCETPIIPEVMPVVGIKQLDRLPQLSDAVFP
DAVKDRMLAVKDDPVAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A6L8K3D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella flavida|TrEMBL
MDNPNFSIEFFPPKTAEGAEKLRVTRAKLSELKPKYFSVTFGAGGTTQRGTLDTVVEILA
AGEDAAPHLSCVGGTRDSIREILTEFKAHNIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGDWFHIEVAAYPEVHPQAKSPQDDLLAFERKVKAGANAAITQYFYNADAYFQFVE
QTTKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLQGGAPGLHFYSMNQAAATTALWQRLV
>A0A1Q7TIM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium 13_1_20CM_4_66_11|TrEMBL
MGTMLYGKGFFLNVCYDELNLKQPRLVQEVHAEYVRAGAEILETNTFGANPLKLNSYGLA
DETEKINRTAAELARAAGGGRVSVVGAIGPLGIRIEPFGPTSQAEAEAVFARQVQGLLAG
GVDGFILETFSDLDEMHAALRAVRAASDLPVVCQMTIGTDGLTYYGTDPDTYTKQLAAWG
ADVIGVNCSVGPAGVLEAVEKMVKASDKPVSGQPNAGLPKDVGDRKIYLASPEYMANYAR
RMIEAGARFVGGCCGSTPEHIKKIRDYVASVVPRQPSVVVSRAQVQPPADVTPVALALKS
RWGSKLARGELVTSVEIVPPKGVDPAPMLDQCRALKRAGVDAVNVPDGPRAQSRMGVLPS
ALLIEREVGIETVIHYCCRDRNLLGMLSDIIGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLTNLVYRLNQGLDPGNNPLGGATKWAIGVGVNPGAGDQDRELSRFAWKVDAGA
EFAVTQPVFDARQLEAFLKRVEQFKTPIVAGIWPLISLRNAEFLANEVPGVSVPDEVLQR
MRKA
>A0A830D2V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phtheirospermum japonicum|TrEMBL
MPINNYKGFLRMTGFCKTKIPAEIMAALEPIKDNEEAVRAYGIHLGAEMCKKIMASGIRT
LHLYTLNMEKSALAILMNLGLIEESKISRPLPWRRPANVFRVKENVRPIFWANRPKSYIS
RTLGWDQFPHGRWEDSQNPSYGALTDYQFMRPRARDKKISEEWATPLKTVEDVCEKFMKF
CLGKLRSSPWSELDGLQPETKIINEQLANVNLKGFLTINSQPAVNGAKSDSPSVGWGGPG
GYVYQKAYLEFFCSLESLNALVEKCKAYPFLTYMAVNKQGNWISNVNNTDVNAVTWGVFP
SKEIVQPTVVDPASFMVWKDEAFELWSRGWAKLYPESDPSRKLLDEMQRNYYLVSLVDND
YVHGDLFAVFQDV
>A0A7H1AZ91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MNRIQKNYQDKINQKINGFYNIIKFSFEVFPPKDLILEEKLWASICCLKELHPSFFSVTY
GANSGEREKTYDITQKIRNKTHILTSPHLTCAGLTATELQKIAEYYWNHGIQSVVALRGD
INSNSYKHTMYAVDLVVLLKKVANFDISVAVYPELHPESKNFESEISNFQKKIDAGANRA
ITQFFFNVESYLNFRDRCVKRGINVEIIPGILPIYNFQQIQRFSSMTNVCIPDWIFKVFH
GLENDISIQKIVGFNIVVDLVQKLYLEGVRHFHFYTLNRSDIVYSICHLLRFKNKCMHNT
FRD
>A0A2D7KBN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ponticaulis sp|TrEMBL
MSLQHAPKDIHVSFEFFPPKSEKAEDTLWESVRRLEPVHPKFVSVTYGAGGSTRDRTHRT
VKRMVEETDLTPAAHLTCVSASKDEVMGVVDDYLDAGVRHIVALRGDPPEGMGAKFTPHP
DGFQSSVDLISAIRHYRPELGKRFEISVAAYPEPHPDSLGLAKDLEILKAKQDAGADRAI
TQFFFEPDHYFEFLDAARGYGIDIPIVPGIMLQPNFNGLKRIATLCGASLPAWLHELYEG
LEGDAEQRELITANVAADLTMKLADRGVKDFHFYTLNKAGLSLATCRLLGIKPDKQAA
>A0A3T0FUZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. ISO98C4|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRLGVEIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1F9YWA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFOXYD2_FULL_34_15|TrEMBL
MKLSDLFSQKKFVVTSEIGPPKGWHLENTLHEAETIKNRVSAINVTDNQSSVMRFGSLAT
CHFLKDKNIEPVYQVVCRDRNRIALQSDILSAAAFGIENLLLLTGDHTKLGDHPQAKSVF
DLDSVSLIHTVKKLEEGFDIAGNKLDGEPPKFCIGAVVSPCSEPLEPQLIKMEKKVKAGA
QFFQTQAIYEVDKFIKFMEKAKQFGVPVMAGIVILKTVGMARYMNENVAGIHVPDNLIEE
LKKDKEKTKSGQTGIEIAARLIKELKPYCEGIHLMPLGWDDKVPQILDLAGL
>A0A1H2RCB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas kuykendallii|TrEMBL
MTSSRPNVSFEFFPAKTEAGHEKLLANARRLAAERPHFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDSKDDLRSLLTQYQAAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRRETGDHFHIEIAAYPEMHPQARGFEDDMANFVRKARAGADSAITQYFFNADAYF
YFVERVRKAGVDTPIVPGIMPVTNYSKLARFSDACGAELPRWMRKQLEAYGDDVQSIQAY
GEQVISAMCERLLAGGAPGLHFYTLNQAEPSLAICSNLGLGA
>H0GFV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae x Saccharomyces kudriavzevii (strain VIN7)|TrEMBL
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRD
AENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDVKLDLEYLKQKID
AGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQH
FSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL
PMESEFNAHPLAVLXWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANKCLELWSTPTSINDVAFLVINYLNGNLKCLPWSDITIN
DEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL
>A0A430R5F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus|TrEMBL
MKIRDLLKARKGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRERS
VLWAKRILDLGLNALAHLTVAGQSQEEVAGVLDRFVEAGVENILALRGDPPQGERVFRPH
PQGFRYAMELVAFIRSRYGEGVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRMGIEIPILPGIMPITSYPQLRRFTEVCGASIPGPLLSRLERYQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNRSPATRRVLERLGFKPT
>A0A653JM55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingorhabdus sp. 109|TrEMBL
MSNPARPLALSELEEAKRALDAPLFAGLSGDADVSFEFFPPKSEKMEKTLWDSVVTLEPL
TPRFVSVTYGAGGTTRERTHATVARIARETDIPAAAHLTCVGASKDEIADVARSYWEAGV
RHIVALRGDPPAEGTAFEPHPHGYASAADLVKGLKDIAPFEISVAAYPETHPEADCPQSD
LDNLKRKLDAGASRAITQFFFTAEAFFRFRDAAAAAGIDAELVPGILPVSNVAQTRKFAG
MCGAEIPGWMNDLFEGLDDHPAARQLIAATVAAELCRKLYAGGVRQFHFYTLNRAELSYA
ICHLLGKRPAGAQQEKAA
>A0A430SDF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus|TrEMBL
MKIRDLLKAQEGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRERS
VLWAKRILGLKLNALAHLTVAGQSQEEVAGVLDRFVEAGVENILALRGDPPQGERVFRPH
PEGFRYAMELVAFIRSRYGEGVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRMGIAIPILPGIMPITSYTQLRRFTEVCGASIPGPLLSRLERYQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGFKPQP
>A0A2D9RJ70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ponticaulis sp|TrEMBL
MSLQVQPKDIHVSFEFFPPKTEKAETTLWDAVRRLEPVGPKFVSVTYGAGGSTRDRTHRT
VKRMVEETSLTPAAHLTCVGATKADVIEVIDEYLDAGVQHIVALRGDPPEGMGAKFQPFE
NGFASSVELIEAIRSHKPALGKKFEISVGAYPEPHPDSQGRAEDLAFLKAKQDAGADRAI
TQFFFEADDYLRFVDDAHDAGITMPIIPGVMLQPNFKGLARIAGLCGAKIPAWLAELYDG
LDDDPQQRELITANVAADLTMKLADKGVKDFHFYTLNKADQALATCRLLGIKPRSKAA
>A0A257WZW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. 12-67-6|TrEMBL
MTLPPTLSGARRVIGPVARAGERGQSQGGGRPRVSFEFFPPKTLAMEESLWQAITRLAPL
DPAFVSVTYGAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASREEVDEVIREYWETGV
RHIVSLRGDPPPTEGGIGGVYAPRADGYANATELTRAVRAIAPFEVLVGVYPEKHPESPS
IEHDIDVLKAKVDAGASLAISQFFFDIDAFLRFNDKVRAAGITIPIVPGIMPVTNFNGLK
KMSQACQTAVPTWLANLFEGLDHDAETRRLIACSVASEMCAKLQEQGFEDFHFYTLNRAD
LVYAICRVLGVRERETASTEVAA
>A0A519TPX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp|TrEMBL
MKVTEHLSRAEGKTLFSFEVLPPRKGENIHTLFSNIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRKRPGTVGICAAIKNRFDVDTVPHLICGGFAKEETENALIDLHFLGIDN
VLALRGDPIKSEGQFQPHPDGHRYACDLIGQISELNHGRYHDHDEQYQPAGAEPVLCTNF
CIGTAGYPEKHFEAPNFGSDIRFLKEKVDRGAEYIVTQMFFDNEEFFKFEKLCRDAGITV
PIIPGLKPLTTKNQLTALPRAFFLSLPEALTEAIHQAKDNAAAREVGIEWCLNQSRELMA
HGVPCLHYYSMGKSEAIRRVAAGLF
>A0A4J2DAK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSCQTPSLSFEVFPPNPAVGNDNIILALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIELIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDDERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A369CTT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AG102|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7Y3US39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SbB1|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFETDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7Y9J5K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora corticicola|TrEMBL
MISCPKRMRYGPCGGVRPSGACELDEALPCPWTSGDPVLAWDGPEPDAPAVVDPPVVLSD
LAVPARDPATLRAVATRLADGADAVLVADLHDRADFPPTMIAATLLELGVRPWITLTCRD
RNRVVLEQEVVGLAALGVGGVLCVTGDSRPGSGAGTTVGAGATQVFDLDATRLAHLVATN
GLVATVTAAPAAPPDPAARAAGLAAKQAAGARLVVTNHVASPAVLDDFLTAGRAAGVSLP
VVAGVAVFTDARTARGLADLPGLALDPDAVARVLDADDPVEAGIEEAVAEARALLALDGV
VGVNLSGVGSSAGWVPAADLKAEVGRRVRAAHRAESESLRPA
>A0A6N2TCT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schaalia odontolytica|TrEMBL
MSQPSDCSSDLTTLSFEVMPPRKESLVKPFWQTVERLLSVSPDFLSVTYGAAGQDRHSAR
GVVRKLVKDSPVQPIAHLTCVGTTPSEVSEVVTDYLNAGVRTFLALRGDPPVGRPDWQPS
PGGVSSATELVTLIRSIEAARCAQYPGAALRAAFKPLTIAVATFPAGNPAVGTSPTQEVE
RLLVKQSAGASFAITQLFWEADTYVNFLEKARSNGVTIPIVPGILPPTDIRRVSRMTELT
GVVFPEYLRRKLESASSPQEMYSMGVEIGGRLARDLHDSGAPGIHMYTFNKAAPALDVLD
AAGLVSASQC
>A0A0Z8QD53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHISTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKTILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVASIHLYTMNNAETARTIHQATHSLFKHYS
>A0A4V1XLI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus sp. CRB-8-3|TrEMBL
MQIQEMVADAEKTGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYFGLETCMHLTCTDMGEEKVNDALAKAYKAGCTNILALRGDPPREKEK
WVATEDKFQYARDLVAHIRQKYGNHFGIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGATF
IVTQMFYDADNFIRWMGKVRERGINVPILPGIMPIATYASFLRRANHMNCKIPESWMTAL
EPVKNDDAAVREVGKTLVAELCRKIMAAGIVHLHFYTMNLAQATRMVLEELDWLPTTTRP
RKQALPWKQSLSLGRREEDVRPIFWRNRNKSYVSRTQEWDEFPNGRWGDSRSPAFGELDA
YGVGLTGTNESNRKKWGEPRCIKDIATLFVRYIEKDLQTLPWSEAPLTAEADSIRDDLIK
LNQRGLLTINSQPAVNGVKSSHPVHGWGPPNGYVYQKAYLELLVPPELFPEIVSRIHDHP
DLTYYAVTRTGPLKTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAYRLGKDW
AHCYDANSPSRVLIDKIMDEWYLVNIVNNDFHQPRTIFELFEGLHVGNLDVHNTPDSNGV
HNESNGDAGHTNGPGTAVTA
>A0A1G0JCW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPLOWO2_02_FULL_57_10|TrEMBL
MTNTPGSDSTQARFSFEFFPPKTEVGEEKLKEVHRQLALLKPDFFSVTYGAGGSTRDGTK
QAVVNIHNAGSNVAPHLSFGGSSEEEIVALLQFYKDLGITRLVALRGDIPSGTGTTSSFF
YANELIELIRRKTGDHFHIEVACYPEIHPKSESYASDLRYFKQKIDAGANSAITQYFYNP
DAYFYYVDNCVEMGIEVPIVPGIMPITNYANLARFSDNCGAEIPRWIRQRLEAFGDDVES
IKSFGEDVVSSLCEVLLEGGAPGLHFYTMNQVGPVGTIWNNLGLSDR
>A0A503B5E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-6-2|TrEMBL
MTVRQIDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFRTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHLLHDEITETQVDMVK
TAH
>A0A1H8E344|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megamonas sp. Calf98-2|TrEMBL
MTRISVELVPRDIEVLKEEVKTIKEKLSDVDFINIPDLLSCDTRSWDGANIAKAYFDDVV
PHLRAMDFDFTKELPIKDKLREYNIKEVLVVEGDPPQSMLYQVYPTISTDIIKKFSEEMP
EITVYAGIDQYRSSMKEEEYRIRRKQLAGAKGFFTQPFFDMRYLEMYADLLDGLDIYWGV
SPVLSERSVSYWRNKNNVIFPKDFEPTLEWNIEFASKVIDFARKHNHNVYLMPIKAKIMP
YLEGVFAK
>A0A3A6ABF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AF25-38AC|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIREVAKQIY
>A0A165QD08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudovibrio sp. Ad26|TrEMBL
MSEHSIDRRFRLNGASDISVSFEFFPPKSEKMEQQLWSSIKRLEPLGPSFVSVTYGAGGS
TRERTHSTVSRIVNETALKPAAHLTCVDATKEEVNEVIRSYWDAGVRHIVALRGDPATGL
GETYHPHEGGYQSTADLVASIRSIGDFEVSVSAYPEKHPESPSWESELDVLKAKVDAGAT
RAITQFFFDNDHYFRYVDRVRAAGINIPIIPGIVPVTSFKGISGFAKKTGASVPGWLAHR
FDGLDDDPRTRELVAAAVAAEQVMSLADDGVEDFHFYTMNKADLVYAICHMLGLRAKQDV
KASVAA
>A0A2A2ENF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas salipaludis|TrEMBL
MSVQEHPLGISFEFFPPNTDAGRDKLVGVRDALAKCGPRFFSVTYGAGGSTQARTSRTVK
MIGESGINTAPHLSCIGSDKGELRELLAQYREEGVNSLVALRGDLPSGMGGIGELRYANE
LVEFIRAETGDHFEIAVAAYPECHPQAPSYEHDLQNFARKMQAGANLAITQYFFSAEAYF
HFVDRARALGVEAPIVPGIMPITNYTKLARFSDACGADIPRWVRKQLEAYGDDSESIQAF
GEEVISRLCQRLLDGGAPGLHFYTLNQATASLRVLDNLA
>A0A0Z8LDJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MFMIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLA
NHVRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYA
TDLISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAF
YNFQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLR
AAGLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A0Z8HCB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLTPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A6Z5TYQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDKAYLAVYPNASLPEVQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLESTKPVLEKEVRPIL
ELVPEEVEDEESGERLLDKVKERLTILVELDPPRTFDTSKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGYANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYVQNKQQLQIASK
>A0A6Q2ZIZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Esox lucius|TrEMBL
MVNQVQTVDDTWRRCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESVLHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPIGTDWEEEEGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAQSYDEDLKHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKENDAAIR
NYGIEHAVGMCRMLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEKSVYEVFTSYIMAEPNQAGHKVMCLPWNDEPLAPETNLLKDELAKVN
RRGVLTINSQPSINGKPSSDSIVGWGPPGGYVFQKAYLEFFTSSENVTALLQVLKKYEPR
VNYHIVNVQGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELMPAVLLDIHSLY
>K0I8Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. KKS102|TrEMBL
MNAAHAQGTGFPVSFEFFPPKTPEGADKLRVARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILSEGVGAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPEADLQAYVTKVRAGADSAITQYFYNSD
AYFRFVEDAHRLGADVPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASI
KAFGLDVVTDLCDQLRTAGVPALHFYTMNQSAATLEICRRLGI
>A0A6Q2Z0I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Esox lucius|TrEMBL
MVNQVQTVDDTWRRCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESVLHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPIGTDWEEEEGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAQSYDEDLKHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKENDAAIR
NYGIEHAVGMCRMLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEKSVYEVFTSYIMAEPNQAGHKVMCLPWNDEPLAPETNLLKDELAKVN
RRGVLTINSQPSINGKPSSDSIVGWGPPGGYVFQKAYLEFFTSSENVTALLQVLKKYEPR
VNYHIVNVQGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDVNPLEQPVDGL
SLGISFD
>D3NT28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. (strain B510)|TrEMBL
MTAPISAPPSISFEFFPPKTEKMEQSLWQSIRRLAPLSPGFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGKYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPEAHPEAPSAQFDLDNLKRKIDAGATRAITQF
FFDNDVYYRFLDRCAAAGIHVPIVPGILPITNFARAVEFADRCGASMPAKLAETFEGLDD
DPETRQLVAATVAAEQCQELQARGVNDFHFYTLNRSDLTIAICRMLGVKAKAAPAAAPVA
G
>A0A2V1JXL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corticimicrobacter populi|TrEMBL
MTKPDLSLEFFPPRDLAAQERLVRTAKQLLAVHPRYVSVTFGAGGSTREGTARTVGTFRN
FGCDAAPHLSCVGSSRDDLRQILQSYREQGVRRVVALRGDLPSGMGPEAGELRYAAELVA
FIREESGDAFHIEVAAYPEMHPQAAGPGEDLAHFAAKVRAGADGAITQYFFNADAYFDFV
ERARTAGVDVPIIPGIMPITNNSQLSRFSAMCGAEIPRWIKLRLNEYGDDRASIKAFGTE
VITDMCRRLLDAGVPGLHFYTLNQADPVLDIWRGLGLDS
>A0A2D7W0H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micrococcales bacterium|TrEMBL
MDGGDLDTVAEAVDRFQPYVDAVNXTDNPAAXAHASNVSMAIAVKQLGLEPIMQVVCRDK
NRLAIQADVVGAXMHGVTSFCALTGDDVTAGDEPEARRVFDIDGPQLVSIMRTLSDGTYL
SGRSLKHHREXLIGAVENPXAPPAHVRVRRARMKVDSGARFLQLQIGYEPEKLEAFVQGC
XDNGVXRDAAXLPTVILTKSAGAXRFMXSSVPGIHVPXDXIDRXASASDPLEESYQLARE
QAAXALSLPGIAGIHITDFRHDDSVHRLVRDLRLGPAFSSEGATTHASTTHTQTA
>A0A413X3G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi|TrEMBL
MKIKDILGQGKPTLSFEVFPPKTEDKYESVERAAAEIAKLKPAFMSVTYGAGGGTSRYTV
DIASTLHHEYQVTALAHVTCVSSTREKVHEVLEELKAAGIENILALRGDIPKDGPVASDY
RFASELIREIRAYGDFCIGAACYPEGHVESVSKTIDMDYLKQKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVVAGIMPVTNVKQIIRSCQLSGTYLPSRFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANGVDAIHVYSMNKPDVAAKIKENLSEILS
>A0A3G8WDY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Avibacterium paragallinarum|TrEMBL
MSYAKEIDTLNHYLSGVNGNINVSFEFFPPKNENMEKILWDSIHRLQVLKPKFVSVTYGA
NSGERDRTHSVVKRIKQETGLEAAPHLTGIDATPEELKRIAQDYWDSGIHRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHLEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPAWLAKMYEGL
DDDPTTRNLVAASVAIDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A3S8Y740|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. W1SF4|TrEMBL
MALGTASTWSDRAHTVRDLLASGTSYSFEFWAPKTEKGERNLWNALRRIEAVSPSFVSVT
YGAGGSTRGGTVRATQQIASDTTLTPVAHLTAVDHSVAELRHVIGQFADAGIRNMLALRG
DPPGDPMGPWVRHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVAKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
DAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A372EY38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium 63075|TrEMBL
MIDDIRHNQPKEALLRSLYEMQKRIPLSFEVFPPKNAEGHAKLFETIDRLAPSADDGFSV
TMSAGGARRDDTVRIAAEIGQRTGRPVMAHLISKGLSHEAALNTADDLWERGIRHILALR
GDRPKAETGTLPAGFDHASGLVAALRDRHDFEIAVAAHPEKHPEAETLDQDMDHLKHKLD
AGAGRAFCQFVLDPAAYGEFVEACGRRGIDSPLIPGLMPMENWPRLKRFARMNGASVPAW
LNELFARAESSPELEPYLAASMTIEHARQLIAYGAPSLHVYTMNRWPLSLAMTAILGGTG
YPNS
>A0A135RYM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum nymphaeae SA-01|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTAMGLSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKNE
YRDTEDSETDDAEDFVWAVDLVKYIRKNYGDYFCIGVAAYPEGHADESHPQGQSFEHDLP
YLVDKVQAGADFIMTQLFFDIKAYENFEKILKEHPSGAFKDIILLPGLMPIQSYQMIKRT
TKLSHAKIPDNLMARLDAAKGDDEKVKQVGVDILSELVEQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDPKLEDEEAIIDDGPGIPVPVAVPAVQLNGLSPIPHPATRTLSN
GRRPSSMGSDPHNRIIVSGSASNPAYETTTAGLMVSEPVNTRANTLAISEGVGAVGREAT
WDDFPNGRWGDARSPAYGEIDGYGVSLHMSVTQAMRLWGTPKTVQDINNLFIRHIKGQLA
AIPWSEEELLPESNIIQQELLELNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKA
FVELFIPSSDWAGLVARLNEVKDNTICFYAANGAGDFVSSDASGGLVLEGTEASTNAVTW
GVFPGKEIITPTIIEEVSFRAWAEEAFKIWGEWAKVYGKGSESEALLERIGSEYWLVNII
HHDYVERDALWKLLSGEKEN
>A0A0K2QW28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Hiyo4|TrEMBL
MSTEAVARIRLEVVPSADLLAQLPAAFDTTGSVSVTCLPHHGPARTVEASMHLARLGYHA
VPHLAARSITGEAELHSLLLQLREASVSELFLVAADRRTQAGPYNWRGELLEAVNAYSTD
FSIGIAGYPEGHPELSQEQLSGSLLTKAPLASSMVTQMCFSAEAISRYLRTIRKGGIELP
VWVGVPGPVSIRKLVSLGARLGVGRSRKLARGSGMADALWRRDDFMSYDGGRLIREVRQE
LAGDPLFAGSMSTPSTTSAVCLASWMICGHCSRPPRWPQAAPPFHFYLPRSEGKITWLQK
PPSRTSTSQN
>A0A174GRP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi|TrEMBL
MKIKDILGQGKPTLSFEVFPPKTEDKYESVEKAAAEIAKLNPAFMSVTYGAGGGTSQYTV
DIASTLHHEYQVTALAHLTCVSSTREKVHQVLEELKTAGIENVLALRGDIPKEGPVASDY
RFASELIREIKACGDFCIGAACYPEGHVESVSKTIDMDYLKQKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVVAGIMPVTNVKQIIRSCQLSGTYLPSRFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANGVDAIHVYSMNKPDVAAKIKENLSEIL
>A0A849G8H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MRFDDEPLIPGEALPILPGHVSHGRLERILRAGLFAVTAEIAPPDSADPHEVYERAALFD
GYVDAINATDGSGANCHMSSVGMCSLLTRRGYAMVMQVSARDRNRIAIQGDVLGASAMGV
SNILCLTGDGIEVGDHPEAKPVFDLDSMSMLEMIRTMRDERRFLSGRKLTEPPRVLLGAA
ANPFGPPLDYRPHRLAKKIEAGAQFIQTQYCFDIERFKEFMKVVRDQGSHEKAFILPGVG
PLASAKSAEWIRTNVPGVHIPDAIIARLKGAKDATQEGIQVCVDMINELKEIEGVHGVHI
MAYRQEHHVGEIVERSQVLGDRVPWHPGDTMENSQ
>A0A7C2PKN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexus sp|TrEMBL
MHSTLQRRLAAGQIVVTGEIAPPKGAARSHLEALARNIRDYVDAVNLTDNQRGIARMSSL
GGSVILQQLGIEPIMQMTCQHRNRIALQADALSAAALGVRNLLAMTGDHPRIGDHPEAKN
VLDLNSFQLIRVLRTLRDQATFQSGTPLKEAPRFFIGSVANPNVERAARLEKKIEAGAEF
VQTQLIFDVGRFRQWMADVRAAGLHQQAYILAGVMILRRPHSAIYLRDHLPGTLMPETVI
ERMQRATDSEAEGITLAAELVNELLSVEGVAGVHIMSVDWTRAIPRVVEQAGLLPRPPVP
STEENVL
>A0A8I0L9T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. Sa1YVA5|TrEMBL
MSSTNISASSQWSISEVLKRPVPGRVPFSVEFMPPRDDAAENRLYRAAEVFHDLGASFVS
VTYGAGGSTRERTARVARRLSRQPLTTLVHLTLVDHTVEELEEILRGYAELGLTNLLALR
GDPPGDPLGEWITSEGGMSYALELIQMIKNSPEFSHFDIGIASFPEGHYRAGSLENDTRY
TLAKLRAGAEYSITQMFFDVEDFLRLRDRLVAADPVHGAKPLIPGLMPITSLRSVRRQVE
LSGSTLPRALEEKLLRAANGDEEANRDEIRKVGIETTSEMAERLIAEGVPDLHFMTLNFT
RATQEVLHNLGMAPAWGAEHGHDAVR
>A0A7C3VKM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktothricoides sp. SpSt-374|TrEMBL
MTNLVLTNHSKIPSSLPPLSRFRQAVRGGEFLITAEVMPPKGADPAHMLNMANCLKDRVH
AVNVTDGSRAVMRMSSMAAAVILLQQGIEPICQFACRDRNQIALQADLMGVHALGIRNVL
ALTGDPVKAGDHPHAKSVFDLEGVRLLQAIAKLNRGVDWNDKPLTDGATDLFAGAAVDPQ
SKSWSGLQRRFEKKLEAGAQFFQSQLVCDFDQLDKFMTKIASQTDKPLLAGIFLLKSAKN
AEFINRNVPGVQIPQHIIDRLAAAHDPLREGVAIAAEQVQLARQLCQGVHMMAVRREDLI
PEILDLAGIPALPTSVVVP
>A0A7X9I5B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MTNRFKESLVDKNVFSVTWELVPGRGAREKAQANAIEAAKEAASEGRIHAVTITDNPGGK
PALSAVGLGMEILQLGMEPLVHFTCKDKNRNQIEAELYAMDRAGVRNVLVMTGDYPTGGF
MGQAKPVFDLDSVQAMDLIAKMNQGLVTGEGAGINRLKPSAFFAGSVVSPFKATESELMT
QYFKLEKKIAAGAGFVVTQLGFDARKFHEVLQYVKTIDADMPVIGNIYVLPFGAARIMHA
NQLPGCVVTEELLARIDRERNEKDQGRSARLLRAAKMYAIMKGMGFDGVHLGGHNIKYEQ
VRYILEQGERLSREWTSLLPEFDFPQPGGFYYYQRDPQTGLNTSQPDDRAGRQPEMNPGI
NYRMMRLLHHWFFTPGKNLFPLMQRYYQGKSNPAKYPLEHALKVAGNSCRDCGDCALLDL
AYLCPMSQCPKNQRNGPCGGSQAGWCEVFPGKKK
>A0A3D1K2R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaeria bacterium|TrEMBL
MKQSLKDKLASQITIFDGAMGTEIYKKNFFVNTCFDELCLTAPRVISQIHKEYFDAGADV
LTTNTYGANFNKLSRFGLGDKIREINRAAVKLARESGNENTLIAGSVGTIGKILHHEKHS
EHHVVEMLAEQIAVLEEAGADFIIFETLPSVADTHFAFMAVNKSSNIPYVMSFALEENAE
TLKGEPLQSLLNVFKDGGRKPDAIGLNCGGGPEGILSSVEKLIRMTELPIIVQPNAGVPK
NVEGRMIYMASPEYFTTYAVRFVNLGVRGVGGCCGTSPKHIRDIARSIRPLAKTAIIEKI
TIKDHEEHLQDPVPMAQKSRLAAKFAKGDWITTVEIVPPKGYDLDSTIEKSKQCKAAGID
AINIPDGPRASSRISPIVTATKIQELAGIETILHFCCRDRNLIGMQSDLLGCAALKINNI
LFITGDPPKLGDYPFASAVFDVDSIGMVTIQSRLNRGVDIGGNSIKEPTKALIGVGADPN
SIDIEREIRRTRDKAAAGAEFIITQPVFAVEPLIKFIEKIGDLNLPVIAGIWPLSSFRNA
EFMKNEVPGVVVPDSIMERMAKAKTKEEQRSTGICIAKESIEKIRSYIRGIQVSAPFGNV
QTAIDVIKS
>A0A7V6RNS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
ACVGHNKAEMEGILADLQDQGIENILALRGDPPKDDKIFDFKKSDYVYAVDLIHEIRNKG
DFGIAAAAYPEGHPECERLIDDLLFLKQKVDAGADFLITQMFFDNRVFYEFVDKAQRLRI
NVPIVAGIMPILNAGQIKRMVYLSGASIPGKLLKLIDQYEHHPEDMKKAGIEYASHQIQD
LLDNHVDGIHLYTMNKWEEILAIAENTGI
>A0A410P366|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Velamenicoccus archaeovorus|TrEMBL
MTFKEKLSSSRFVLTSEVGPPKGISLEKILKEIAPLRGRVDAINVTDLQSSVMRMSSLAA
SIQIKGAGFEPVLQMTCRDRNRLALQSDILSAASFGIENILALTGDHPALGDHPQAKPVF
DIDAVTLIGILRTLERGADMNGNPLLGQPPKFCVGAAVNPGADPLEPELIKMEKKIAAGV
EFFQTQAIFDIGSFEAFLAKTRHLKTKIIAGIMLLKSERMARYMNENIPGVAVPEAVIAE
MENSTDKKQKCLEIAVRLFKTLQPMCDGIHFMPIGWYGMVPRLLDAVG
>A0A7V1UKW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriales bacterium|TrEMBL
MTSNFLRRLKKGPVLCDGAMGTLLYEQGIFINRCYDELNLSQPELIRDIHLQYLAAGAEL
IETNTFGANSFRLARHGLAEKVREINVKGAKLAREAITRKKAEAFVAGSIGPIGVRIEPL
GKIAREEARLAFKKQAQALAEGGVDVFLLETFGYLDEIRQAILACREVDPQIPVIAQVTI
DEDGNCLDGASPETFAQKLTDWGADVIGCNCSVGPVAMLEAIERVRAATTRPLAAQPNAG
MPRSVEGRNIYLCSPEYMASYARKFLTAGVQVIGGCCGTTPDHIHEMAAILKTTGAKAQK
FTAKKAPSVETDVAVPPLETRSKLGAKVARGEFVTMVEIVPPKGIDPSKEIAGAQFLKSV
GVDAINIPDSPRASARMSNVMLCVLVQQQTGIETVLHYTCRDRNVLGIQSDLLGVSAIGL
RNILCITGDPPKMGNYPDATAVFDIDSIGLVNVAANLNRGLDIGNNPVGASTGFTIGVGA
NPGVPELEEEIHRFEYKVEAGAEYVITQPVFDLKLLEQFLKRIEHCRIPVVAGIWPLTSV
RNAEFMKNELRVSVPDEIIRRMASAKSAEAAREEGIQIAREMLLAVRSVVQGAQISAPLG
RYTSAVDVLEALGSSAGAKA
>A0A7X6WJV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MKSGSNLEKVLRAGHFAVTTEIGPPKSCDAEVVRRHGETLRGYADAYNVTDNQTAVVRLS
SMAACTILTGMGLEPVLQMTCRDRNRIALQSDLLGAAALGIRNVLCLTGDHQSFGNHPDS
KNVFDLDSIQLIHTARLMRDKGQFLCGEEMKVKPRLFIGGVVNPFADPFEFRVTRLAKKN
AAGADFVQTQAILDMSRFERFMKKVREAGLHEQVFILAGLMPIKSARMARYMQKNVPGMM
VSEEICQRLEKAEDVKAEAVKLVVEQIEQIRQIEGVAGVHLMAVAWEEIIPAIVEQAGLY
PRPSL
>A0A3S2BSF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.001.02.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWET
>A0A087K9D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. JS01|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKA
TQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPESLKERILAAKDDP
AAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>C2FDC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei subsp. paracasei ATCC 25302 = DSM 5622 = JCM 8130|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A1L9VEM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus glaucus CBS 516.65|TrEMBL
MHVKEKLAQNEANGKTGISFEFFPPKTAQGVQNLYDRMDRMHSLGPEFIDVTWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAALHAAYKAGCTNILALRGDPPRDKEH
WEVADGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKIDAGSSF
VITQMFYDTDTFINWVKKCRAKGIAVPILPGIMPIQTYAAFLRRANWTKAHIPQDWLDAL
EPVKNDDAAVRDIGKTLIANMCRRLLDSGLIKHLHFYTMNLQQATQLVLEELNLVPSEET
PLPKPLPWRPSLGLKRRGEDVRPIFWRNRNSSYIARTQTWDEYPNGRWTDSRSPAFGELD
AYGVGLKGTNEQNIKLWGEPKSVQDITTIFIRYLKGQLSRLPWSDTAISGEANAIMENLI
NLNSRGFLTINSQPAVNGAKSSHPVHGWGPKNGYVYQKAYLELLVPNDVVDELISRIEKN
VDLTYHAVSKTGELRTNTLDSPNALTWGIFAGREVIQPTIVETVSFLAWKDEAYRLGEDW
AKCHDAASPSRKLIQNLVDNWSLVNIVNNDFHNTYDIYKLFDGLNVKDLDVKVSGDAPVP
QQNGAPAEAAAAN
>A0A1H0MXX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedococcus dokdonensis|TrEMBL
MVQGPTPRDGRPRQEPPSIPALLAADHPSVSFEFFPPKDDAGELALWDAIRRLESVRPDF
VSVTYGAGGSNQDRTVRVTERIARETTLTPLAHLTCVGASVAALRQVVGLYAASGVRNIL
ALRGDPPGDPGGAWTAHPEGLNHATDLVELVRTLGDFTIGVAAFPDVHPASPSFEHDVDV
MVRKADAGATFAITQMVFDADTYLRLRDAVAQRRDLPITPGLMPVTNFKQVARMSELMGT
PLPEAVVRRLEAVSDDPAATREVGVTIATELADRMLSEGAPGLHFITMNRSTATLEVYRN
LDLGARAASRA
>A0A4Q2QSB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae complex sp. 743-2DZ2F-22B|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVA
>A0A517ZE64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maioricimonas rarisocia|TrEMBL
MRIPEIYREGQFGLSIEIFPPKSEQGDRVLWSTLERLRGYAPAFISCTYGAGGTTRTRTV
EICREIHERFELTTTAHFTCVGATREELIDWLKYASENGIGNIMALRGDAPQGQESFETP
PGGLCYANELVSLIRENVPDVGIGVAGYPEKHPEAATAEIDLANLKRKVDAGADAVFTQL
FFDNSNFFRFRDAYQAAGITVPLIPGIMPITEFARIKRITAMCGAVFPTELASRLEAVQD
DAEAQFEIGVEYAISQCRELVDAGVPGMHFYVLNKSQACERILDSLGLATPVA
>A0A498BTW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalispirillum mobile|TrEMBL
MVKTDNMESQKQHTPVYSCEFFPPRTERGVEKLRTTRERLAQLNPAYFSVTFGAGGSTRD
RTFETVTEIHRSGLEAAPHISCIGSTRESIAELLHNYREQGIRRIVALRGDMPSGTRDVG
EFRYANELVAFIREETGDHFKIEVACYPEFHPQARDAEADLDNFARKVEAGADAAITQYF
YNADAYFHFVEQAEQRGVTVPIVPGIMPIINFKQLARFSDACGAEIPRWLRKRLEACGDD
KVAIQALGHQVVADLCRRLLDGGAPGVHFYSMNQAGPVERLWADLDLPR
>A0A1F3GD07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWE2_39_28|TrEMBL
MTVLEKIQTAKKPLFTFELLPPLKGHSIDKVYASIEGLLEFNPAYINFTSHRNETLIRER
PDGSLERRVARIRPGTIALAAAVKYKYDITVVPHVLCGGFTREETENALIEMNFLGIHDV
LALRGDPVRGSRSFIPEKDGHENADGLVRQIVNLNSGRYLDETMEHAVPTSFCIGVAGYP
EKHFESPNMEADIAWLKAKVDAGAHYIVTQMFFDNAKFFRFVEACRAAGISVPIIAGLKP
ISALNDIRLLPQTFHIDVPNDLYKAVAACKDDVAVREVGVEWATMQSRELLKAGVPGIHY
YTLGRSDNVAKIVRGSF
>A0A354U7L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaeria bacterium|TrEMBL
MQADLLGCAAMNINNILFITGDPPKLGDYPFASGVFDMDSIGMVRVQSRLNRGVDLAGKP
IDAPTKAFIAVGADPNALDMEREIRRSREKIEAGAEAFITQPVFDIEPLLRFIDAVPELR
DGTIPVIAGIWPLASYRNAEFMRNEVPGVVVPDSVMERMAKPATKEEQRKVGIQIAREAI
TAIRGRVAGAQISAPFGNVNTAIAVMRK
>A0A5D3B911|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus floricola|TrEMBL
MKITDKLQKAEKEGRPFWSFEYFPPRTAQGLQNLFDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVEICQSTIGIETCMHLCCTEMPKEKVEWALKQAKQNGCQNILALRGDPVAGTST
WEPTPGGFMNAIDLVKYIHKNYPGDFCVAVAGFPQGHPESPLTPEGKEQEMKWLKEKVDA
GSDFIFTQMFYDTDIFFDWVKRVRAAGITVPIIPGIMPIQNWEKFDKWVQRENIIVPQHF
YDALNPVKGDDEKVRQVGTKLVAEMCRKILENKEAGIKGLHVYTLNLEKGARMLLQELGF
EGRREQIAPLPWRPSLTPNRRDETIRPIFWANRTRSYISRTEDWDEFPNGRWGDSRSPAY
GDLDGYPVSIGISANEAYGLWGNPTTTAEIYDLFARFCRGELTKLPWSTQPPASETSVIT
DQLTKMNELGYLTINSQPAVDGVASDDKVHGWGPSGGYVYQKAYLEFFVSPELLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIIQPTIVEAVSFVAWKDEAFE
LGLQWANLYPAGSPSRELVTKVMNNSYLVNIVANDFRDGLSIFEPFLLDQTPVGKVVEGV
KGVVEGVVEGVKSVVTE
>A0A649YKQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. THAF191d|TrEMBL
MVQLPHGESKMGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKT
LKPKFVSVTYGANSGERDRTHSIIKEIKAETGLIAAPHLTCIDASREELARIADDYWANG
IQSIVALRGDIPPGGGKPEMYASDLVKLLKERHDFDISVAAFPEVHPEAKSAQADLLNLK
RKVDAGANRAITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVK
VPSWMAKQFEGLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTL
GVRPQV
>A0A7X0MW39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoteredinibacter isoporae|TrEMBL
MSNEHIPVSFEFFPPKTPAGKEKLAAVQEELALFQPEFYSVTYGAGGSTRDSTKGIVLSS
INAGHDTAPHLSFGGDDEDTIKQLLQEYKDGGVKRLVALRGDMPSGMGGASQLVYANQLV
AFIREHFGDHFHIEVAAYPEIHPEARSYKKDIEYLKGKFDAGANSAITQYFYNPDAYFYF
ADQCQAAGIEQPIVPGIMPIINYKNLARFSANCGAEIPRWMARRLEDFADDQESIISFGI
DLVSDLCEMLLDNGAPGLHFYTMNQTQPTAQILTNLLASE
>A0A074LNR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tumebacillus flagellatus|TrEMBL
MNSQHAFRARLRSDVLVGDGAMATLLYLQGNAIGASTEELCLTEPDWVRDVHAAYLEAGA
TVIETNSYAANRDSLARYGLETRTTRINRASVQIARQAVEESGREAFVIGSVGSILAGRV
RGSEWEEYRDIYEEQAVALLHEGVDGLILETFYDLEELLLALDVIRPLAASSGTPIISQL
SLLEVGRTRDGYELTQAFRQLQAAGTDVVGLNCRLGPAEMLGSLEKAIVPEGMPISVYPN
AGRLGMIDGKVQYKSNAAYFGDYATRLLNQGVALIGGCCGTAPEHIRAIADSVAGQKRVP
RINPVLQTRVETPERETPRIEFPPTANIVDLVKQRHTIIVEYDTPRDLDIEKYIAGSKAL
QEAGADAITLADNSLATTRVSNMALGAILKRELGIEAIAHVACRDRNLIGQQSHLLGLHA
LGLNQVLVITGDPARVGDLPGATSVFDLSSFDLVRMVKQLNEGIAFSGRRMKNKARFVVG
AAFNPHVRNLEPAIARLERKVEAGADFIMTQPVYDAETLLAIREATKHIPVPIFIGVMPL
TGPRNAEFLHNEVPGIKIAESTLQRIKRFEGVEARHEGVQIAKELLDVAVQHFNGLYLIT
PFNYYDMTVELTRYVREITSPQAEIAAAADPLHHRHGLGCNCC
>X0ZX22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
LAKKVNAGVDFIQTQLVYNVEKFKEYMKKVREMDLHEKVYILAGVGPIKSVGMAKYMQKN
VAGMDVPDKIVERLKKSKDTKEEGINICVDIIQIN
>X0UN61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSTKTPSRLEKILAAGHMAVTSECGPPRGSKGEVITKKAEMIKDYVDAINITDNQTSVTR
LCSLAACIRLKLMGLEPILQMVTRDRNRIALQSDILGAASFDLYNILCLSGDHQQFGDS
>A0A7W8FW96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catenisphaera adipataccumulans|TrEMBL
MKIIDILNQDQVTLSFEVFPPKKADTYDVVEQAARAIASLHPDFMSITYGAGGGTSQYTA
DLAADLHDRMGVEVLPHLTCVSSDRAHVHKMIKTYQEKGIENIMALRGDLPKDGHRSQDY
TYAYELIQDIKAQGDFCIGGACYPEGHIECAHKADDIQHLKNKVEAGCDFLTTQMFFDNT
IFYNFLYRIREAGIQVPVLAGIMPITNPRQLQRSVQMSGTNVPERFRAIVDYFGDDPKAM
EQAGIIYASEQIIDLIANGIKHIHVYSMNKPEVAAAIQANISAMLRS
>X1NLD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
DRNRIALQMDILGISAFGMNNILCLSGDPVSFGNQPEAKPVFDLNSTQFIKMVKVLRDEK
KFENGEPISGKEPRLFIGAVANPFAEPQEHESVHPGEKVAAGADFIQTLAVYNIEKFNKW
MELVRGEGLHKKVKILAGITPITSAAAARYMKTKIPNMDIPDEIIERLRKVRNREEMIEE
GIKIAIETINHLREIEGIAGIHIMTLQREELIPKICSTVGLHPRP
>A0A0F9S4J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MVKRKAFSNLMKELESGKFVFTGELEPTKMYDLSTVLHSAEEMKKTGKIVAANVTDGPQG
DAYTCSMVPSYLVQEKVGLEAVWQMTVRDRNRIALFGDVVGGAILGLKNILTLTGDHTAL
GDNKRARPVYDIDSTQFIDLVSKIIDDGNDLEGKEIEGGPIEMNIGCAANPNARPPYLEP
EILKVGRKVEAGVDFIQTQTAFDIDEAKEFLKELEKYNVPILLGLFPLKNYGIASYFDKF
IPGVSVPKDLLSALKKAKKDFKEDKKKRNERIDQINIDFYEPFIKEIKKTTKARGIHCMA
VHYERLFGPLLKDF
>X1AY30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MNKEMKSGSNLEKLLSRGKFVVTAELGPPKGVNINAIIDKVKILKGFCDAVNITDNQTSI
VRMSSISSAIKIIQLGMEPIIQMVTRDRNRIALQSDLIGAAALGVKNVLCLTGDHQCFGN
HPSSKNVFDIDSIQLIKMFKDMRDEHKFQCGEEMKHPPNIFIGAAANPFADPFDFRPIRL
AKKVNAGVDFIQTQLVYNVEKFKEYMKKVREMDLHEKVYILAGVGPIKSVGMAKYMQKNV
AGMDVPDKIVERLKKSKDTKEEGINICVDIIQEIKEIEGVSGVHIMAIAWEEAVPIIVEK
TGLLPRPKPQKNRK
>Q4L331|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus haemolyticus (strain JCSC1435)|TrEMBL
MSRLLNQLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVESIHRSYIEAGADIIQT
NTYGANFEKLRRFGLEHKVKDIHKAAVAIAKRAARPDTFILGTVGGFRSLQQEELPLSTI
QYHAENQIDTLVEEGVDGLLFETYYDLEELTNIVTTTRRKYDIPIIAQLTASNTNYLVDG
TEINKALQQLVACGANVVGLNCHHGPHHMQRSFSHIELPETAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPQHIAYIKSSVKDLKPVKNKNVIPINRQT
NRAVTHTYKHNLTTKVKNGPTVIVELDTPKHLDTDLFFENIGKLDEANIDAVTLADNSLA
TVRVSNIAAASIIRQRYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMNYFITQPVYSKEKIKEVYEATKHLNVPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLSQFKAVKDDKEKTKALSLRLSKELIDTVHEYFNGLYIITPFQRIDYSLELAAY
SKAITQNKEAIS
>A0A0R1FTQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei DSM 12361 = ATCC 700308|TrEMBL
MRKQTFSVEIEANPGDLRQMKHYLHKWKPDFVSISNLSRYSYEEMVQCARYIQTDLHIPV
VIHLTGLTHTKEQIKKSFNELMGLNIRNFLLVRGNIHHNMHIEDDFNYASDLIKYVNQLD
KDSQIHVIAGCYPDIHALANSLTEDIKYLKEKVDSGVDSLISLMCFDNNRIYKFLDKSRE
YDIDVPIRIGIMPITDPFKRHYLAHNNIKMPAFSEEEDNLLENGINYAVNQINDLYEHNV
NGIHLYTHNDWMVSDRVFENIKKNL
>A0A425WB49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriaceae bacterium|TrEMBL
MRIDELLKTKQTYSYEIFPPKGTMPLADARRVAEALAQDHPDWISTTFSAGGTGSSSHTA
EICDTVQNGLGITSLAHLTCLGSSKEDVERYVGKLDQAGVSNVLALRGDRAPGRDAIDFT
YASDLISYLKTQHPELCLGAACYPEGHVESPSMRRSLENLKRKQDAGADFFVTQLFFDNE
TFYRFRDLCARARIKIPIVVGIMPFTSQKQITRMAFTCGASIPSAVIKRIIAAGDDPAEQ
AKAGVAYAIEQLQDLAQNGVDGLHIYTMNKPAMAHEIHEALVGCGYLAS
>J0MXS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. MSTE9|TrEMBL
MRTADLFKKKQVLSLEVFPPKRTSSEDTIFNTLEELKWLHPDFISVTYGAGGSANNSKTL
EIASFIKTNYAVESVAHLPCINFSKEELLLLLDLLKEQGIENILALRGDISPEHPPCTDF
SHADDLIAFIKEHADFNIIGACYPEGHVESKSTLEDIHYLKRKVDAGTDHLITQLFLDND
YFYAFRERTALAGINVPIEAGIMPVVNKKQIERMVSLCGVQLPKKFVKMMERYEHDPIAM
RDAGIAYAINQIVDLLAQGVDGIHLYTMNNPYIARKIYEAVFRLLAA
>A0A3M7G0S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGVRNILALRGDPPRSDE
YNDPNNPLSEQDDSNKDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLAEKTAAGADFIMTQLFFDVEAYNNYEKRLRSHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLSRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTL
NLEKVVMQILERTGLIPPATPVIKSADRNGITEQAVAEEESDGFLMVEDAKRNRQRRKSS
NRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPINSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLKGEIEA
MPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSTDPIYGWGPKNGFVFQKPF
VELFLPSADWQRLKPILQSDDQVTYYAGNAAGEFQSSDENSVNPVTWGTFAGKEIITPTI
IEADSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDA
LIAA
>A0A3M7B739|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGIRNILALRGDPPRSDE
YNDPNNPLSEQDDSNRDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLVEKTAAGADFIMTQLFFDVEAYNDYEKRLRSHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLRRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTL
NLEKVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSS
NRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPVNSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLQGEIEA
MPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSNDPIYGWGPKNGFVFQKPF
VELFLPSADWQRLKPVLQADDQVTYYAGNAAGDFQSSDENSVNPVTWGTFAGKEIITPTI
IEGDSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDA
LIAA
>E6SBW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP)|TrEMBL
MAHGTASSMTRAERFTRSLAAMVKADTPTFSFEFFPPKDDAAAEQLWGAIRSLEKVSPSF
ISITYGAGGSTRDRTVRLTQRVLEETSLTPMAHLTCVGHSVGELRQVVGHYAAAGVRNIL
ALRGDPQGGLGQPWVAHPQGLNHADELVGLIKGLGDFTVGVAAFPDGHPESRSVEDDVET
LLRKEREGAEFAITQMVFDVDNYLRLRDELARRGSQLPVVPGLMPITNARQVVRMAELAG
QPMPQAVIDRLERHRDDAEAVRREGLAIATEAARRMLDEGAPGIHFITMNRSSATLEVYG
NL
>A0A1V5FMJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division BRC1 bacterium ADurb.BinA292|TrEMBL
MSVQRDIANKVYHIELLTPKQNTETLEDDLAKFAEKFNQIMEAGYVACITDNPMGNISFQ
ATDIIPELGLTPKPGQLSLHLNTFHTREDLHKILDTAAGLGIHDVLVISGDGNERLAKLQ
PAQLGLSCNVVTSVELTAYIRKTWPGVFSIGVAFNPYEPQDHEMEKMHRKIDAGAEFICT
QPVLGKDDRVLALSALGLPVFVECWMSKKLHLLSECVGYTIPEDTPYDPMKNLKELQATY
AGHGMYLAMLGYKTQFPLLKGFWT
>A0A0F7TUG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium brasilianum|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRALVDMALEEAKVLGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRKQHGDYFCIGVAAYPEGHPADSFQDVQDPVRDLPY
LIEKTQAGADFIMTQLTYDIEAYQKFENMLRNHESGVFKTIPIIPGLMPIHSYKILTRVT
KLSHVHIPDPIAKRMEELKHDDDAVKRAGVDIVSEIVGGMQELKSPGPRGFHFYTLNLEK
TVSFILERCDLIPASTDIEDDYAIVEADGIVPLGASARLARRRASSINSQPHNRVIVDKL
SSKVSSHDSVHEALANSVGQPAMPPGRGTTLQISEGLGSLGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTSAVARRIWGHPVEPSDISTLFRRHVSGELYMVPWSEGGAEEGTGL
NAETELIRPELLKLIDGRGWWTLASQPAVNGVRSDHHIFGWGPQREGFVFQKPFVEFFCS
SKDYDTILKPLFAKHGHDKLVWFATNNTGAFESSLPVQPADVELDDLNSNPESVNAVTWG
VFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTERFLDTTKNDTWLVCVVG
QQFGAGTPQGSKEEEDEVKWMWRVLAGETQ
>A0A5Q0NR11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. dk884|TrEMBL
MWRRCRGHRGCVSGEQGCPKRMTFGPCGGVRDDASCELDRRPCPFAQPPAEVVRWPAETA
PPGRSSPPSRLLDAARSGPVVLSDLTTPAYDSAGLAAVVDVLCGSCDAVLVGEHQSRPDF
PPALMSTLVAQAGGTPWVTLTCRDRNRVVLEQELAGLALTGVDGVLCVTGDVRAPGVRSG
VSQVFDLDGTRLAALARERGHAVAVPEAPAAVPRALRPARLLQKQRAGAHLGVLNHVATP
REVADFVAAARALGVTIPVIAAVAVYTDERSARVLQRFPGLHLEDDRVEAVLGAPDVREA
GIEAAVAEARALLAVEGVVGVNLSGLASGEGELAGARVKAEIGERIREGR
>B1FL06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia ambifaria IOP40-10|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRADLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFTQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNAASATRTICERLAM
>A0A2E0UXC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MSLLTKLLKEQKPILSDGAMGTVLHHRDFVVDHCFEELNLSNPAIVAEVHREYIEAGANI
IQTNTFGANRYKLGKFGLDQKVAEINIAGVELLKRVISASFREVFIAGDVGPLGVRIAPF
GRVQLDEARTAFREQISALNEAGVDLIIIETMADFYEVREAIKATRDVNPQLPVLASMTF
TRDDRTLLGDTPEKIAKEIHEAGADIIGINCSGGPLQLLRLLKKMKKAVPDGYYSVMPNA
GWPEQQDGRIMYPAGADYFGQYAVSFWQAGANVIGGCCGTTPAHIRAMAKEIQNTPLDEV
VIGLEVSQMDVEPVEEVDCDCSHMAEKMNAGQFIISVEMDPPRGLSTEKIMAGASLLAEA
GADVINVADSPMARMRMSPWAVCSLIQKNVNIESVLHFPTRGRNLLRVQGDLLAAHALGV
RNVFVVMGDPTAIGDYPEAMDNYDLVPSGLVKMIKQSLNAGYDHAGSQIGQPTSFFVGSA
LSLAPANMETELKNLKRKLNAGADFVLTQPVYDVEAAKKSLNWFRSHLDQPLNVLVGILP
LVTDRHATFLHNEVPGINIPTKIMDRMTKSGDQSPQEGIKIAVELIEGLKSSVQGIYLMP
PFNRFDYAAEIIDQVR
>A0A7M2X1W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MRIDEVAGHGKPIVSFEFFPPKTDAGFQSLFATIEELRPLQPSYVSVTYGAGGSTREKTV
DLVVRIQRDIGIRAMAHLTCVGHTADQIGSVLDDLWAGGIRNVLALRGDPQVGQTTFTKT
EGGFGYANELVGYVAGRHNFCIGVAGYPEGHPQCLNRSRDLEHLKQKVDAGANVIITQLF
FDNADFYHFRDEARRMGIKVPIVAGIMPITNVAQIKRFVSMCGAKIPHPLLQKLESLEAD
PEAVYQYGIDYATQQCADLLKQGIDGLHYYTLNKSKATVDIVKRLRASGAV
>A0A7J7CIW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tripterygium wilfordii|TrEMBL
MKVIDKIRAGTEGVGEGNVVFSFEYFPPKTEDGVDNLFERMDRMVAHNPTFCDITWGAGG
STADLTLDIANKMQNVICVETMMHLTCTNMPVDKIDHALTTIKSNGIQNVLALRGDPPHG
QDKFVQIEGGFSCALDLVKHIRSEYGDYFGITVAGYPEAHPDAIGPDGVATPESYTNDLT
YLKKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFC
KTKIPAEVTAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALAIL
MNLGVIEESKVSRSLPWRPPTNIFRVKEDVRPIFWANRPKSYLSRTLGWDQYPHGRWGDS
GNPSYGALSDYQFMRPRSRDKKLHEEWAVPLKNIDDIYEKFKQFCLGKLRSSPWTELDGL
QPETKIINEHLGKINLKGFLTINSQPAVNGERSDSPTVGWGGPGGYVYQKAYLEFFCSKE
KLNLLVEKCKAFPSISFVATNKVGVWISNVSKTDVNAVTWGVFPAKEIIQPTVVDPASFM
VWKDEAFEIWSRGWANMYPEGDLSRKLIEEVQSSYFLVSLVDNDYIHGDIFAVFADF
>A0A3C0WRB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MNCAKRSWQXPAKVARKLREAGADVIGVNCSGGPNQILRILKQMVQAVPQGKFSVMPNAG
WPEQVAGRIMYPASPEYFADYALAFWHAGACLIGGCCGTTPKHIAVMHQAIENAPSGSAP
NGFTLTAVEREEAAPEGMQPTQLAEKLANGQFVFAVEVDPPRGLTAQKLMAGSSLLKEAG
ADVINVADSPMARMRMSPWAVCRLIQEKVGMETVLHFPTRGRNLLRVQGDLLAAHALGVR
NVFVVMGDPTAIGDYPDAMDNYDLVPSGLIKLIKQGFNTGVDHAGADIGQPTSFFAGCAL
NLTAADPDNEIKNLRRKLRAGADFILTQPIYDPPAAKAFIERAAEELGGLKVPVLIGLLP
LVSARHAAFLQHEVPGIEIPDDVQSRMTLSGEREARTGIEIAIELIHQIKQFAQGIYLMP
AFNRFDYAAEIIETIREGN
>A0A7V2IRA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MQNRELKRVLTDRSGFAVVAELTGGPRYNFAPIERFLSDYRNADTAAAPDGFDFVGITLP
QNPGGVANIEPGDVLAKVQQADLLGDLEVIPHISCKDLNADALLSSLVGFRERGVRTVLA
LTGDKPLTAKGVFDLDSVTLLKLISRLNRDAWLAARPGQWQQVPILTAGAAVSPFKYTEA
SQMQQYFKMEKKLAAGAAFLITQVGWDWRKSAELMRYLEECHLDVPVVGNVYLLSKATPA
ARLMHDGALPGCYVSDGLFETVMNETIEQAVSRAAQQVAMYRALGAAGVDLGGLPDYATF
AEILNQAAQIGTDWEAYKENLSFGPGEGAFYLYDEQGRRTTTATARRGFRRRWFEMMHRA
MLDPEHTGFRALRGTMRALGAERGRGVAYRGFHAMERAAKYVLFECEDCGDCYLPENFGY
CTLGGCAKGLANSPCGDATVDGHCGNDTEQPCRGEQIYYAAAATPGGMERLRGALHEPRN
PTLAHTSSILNYLFGRDHTMGNALISIGEAIHASIPKTGKVMKELVDLGDGAYEKDSGPL
SYMRALIEDQAEEGADYIAINVDAFGENDPQLAIDLMVQYVKLVRRWGRGVPVCLDSSDD
AVLKAGLVEWYRDGTDGPKPLVNSIKVYTADAMMPLKKDYDFAFIGLLVSEDKAQGPGGS
HSVEELLALAEELFDKAMQHGFKPDEIFFDSTVFPLAIDMPMEPGVPGYTYRAFETIRRI
RSNPKFKGVHCSLGISNCCRDLPGRRIGICRAYVAKAMEHGLDAGIVNVGHHYGRKEVDP
GLYELVDAFAKMDGSAEATNKAMMLMGRFCAENRKA
>A0A8E0X4Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFERFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIDAL
KQAKSFLTKHHYSQQILACVMPLTLGRANFMVKYKVAGIVITPYMLKVLADEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLSLKALEELWNSLWQIT
SGKEFSPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALVAK
VLIKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A2N2IJK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-16|TrEMBL
KNRNQMESLLFAWDRLGIRDLLVITGDYPQEGYQGCPKPVFDLGSVHVLDLISRMNKGNY
GPDRGKGAIQPTSFLMGVALSPFKRLEAELLMQYAKLHRKAEQGADYIITQVGYDARKFH
ELLQYVQQSNLNLPVLGNVFIPNLTVAALMHTGKIPGCIITDRLYGEIRREATSPDKGKQ
ARLLRGAKLLAILKGLGYAGAHLGGPGLTYENIDYLLSTADSLAGNWQDLVPEMDYWHQD
GFYLYTKDAATGLNTTEPAPRDERQAGLQVNYRMARLVHNLAFTKDAPLYPACKKICLAL
EGGGLDNGLTHLEHVTKFLLFGCQNCGDCTLGDLAFVCPQAGCAKYLLNGPCGGSRDGWC
EVYPGKKRCLYVRVYERLAAHGL
>A0A259KZG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 39-66-18|TrEMBL
MAGPIRASREIGKAPVGVSFEFFPPKSEEMERNLWTSVARLAPLAPRFVSVTYGAGGSTR
ERTHATVERLVRETDLAPAAHLTCVAATRAEIDDVVRAYAKAGVKHIVALRGDPTSGVGT
TYEPHPDGYAHACDLVAGIRRLGDFEVSVSAYPEKHPESPSIDADIDYLKEKVDNGATRA
ITQFFFDNDVYFRYLDKVRARGIDIPILPGILPVTNFKQAANFATRTGASVPDWLAKRFE
GLDNDPETRKLIAAAVAAEQATDLVDRGAGDIHFYTLNRADLVYAICHLLGLRDKGVAST
APQAIAV
>A0A5V9GLR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Wandsworth|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>I6CDQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella flexneri K-315|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2P7SN21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium soli|TrEMBL
MATPRPPHPDENPAGIDLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSANPQDVYE
RAAIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQ
VFLGAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRDFMERARDLGFTEKVF
VLCGVGPLASAKTAKWIRSNVPGVHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEIPG
VSGIHVMAYRQEEYVAEMVHESGVLKGRKPWKREVRADDQMVADRLDHILHDDATQQPVQ
LVEKAAH
>A0A2T0R185|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineococcus rhizosphaerae|TrEMBL
MTLAPLVAGAAGRPTLSFELFPPRSDAGRDALWRKLSELLSAAPDFVSVTFGAAGATRGP
SRDLLAHVLSTTAVPAMAHLTCVGSSRREVVELATEFLDAGVRNVLALRGDPPAGAADWT
PHPDGVTTASDLVELLQVADRRRLALRGGARPVDEGSLSLAVAAFPRARDDHELAVLRAK
QDAGAQFAVCQVTFSAEEYATFVRRARAAGITIPLLPGIAVSDDPRRFQRIGELTGVPAS
PALLAALDTDDATARLRAATAFSSGLAHGLLDTGAPGLHLYTFNAAAPALDLIDHLDLPR
SVEGRDRVAVGGPTR
>A0A5C6E1M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novipirellula artificiosorum|TrEMBL
MTLASHYSSSRCAISFELFPPKTPAGMQALVKNVKRLTEFGPSYFTCTYGAGGSTRGTTL
DVVEQVKRVTGLPVASHLTCVGSTVDQLADYLVEASQRGAEYIVALRGDPPKGSDRFEAV
EGGLRYANELVELIRQRFAGLGIAVAGYPEVHQEAPDAKTDLDNLKRKVDAGADIVVSQL
FYNNDDFYRFRDACVAAGISIPIVPGILPVTNYKQAERIAAMCKAAIPASLANAMSENDD
EDYQFNVGVEHARAQTVDLIENNAAGIHYYVLNKSEAAAKMLDGLELATG
>A0A3C0YSA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
DEKSLFKFLELTNDCKIPVIAGIWPFTSYKNAEFMANEVPGVVVPSEILHRMSKTKDQQD
GKRTGVQIAMELMDKIKDVVAGYAISAPFGNVNMALACAGKIGIDKI
>A0A1I6KIC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mitsuaria sp. PDC51|TrEMBL
MTTPVSIEFFPPNTPVGTEKLKTVVQELRAVNPQYFSVTYGAGGSTREKTLSTVADIASQ
GFDAAPHLSCVGSTRENIAEILATYRAQDIRRVVALRGDLPSGTATAGEFRYAAELVRFI
RETQGEDWDIEVAAYPEYHPQQRYAARDLQFFADKVRAGASGAITQFFYNPDAYFHFVEA
SRALGVEVPIVPGVMPINNYARIAQFAQRDGIEIPRWVALKMEGYMDDAASVRAFGLDVV
TRLCERLIAGGVPGLHFYTLNQSALTLELCKRLGLAAQA
>A0A6L9HRM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKISDILCQDRVGLSCELFPPKSGSQLKNVQEVVKEVAHLKPSYMSITYGAAGGTSEYTV
EIADEIQNRNHVPALAHLTCVSSTRQKVHSVIARLRQANIENILALRGDIPSDADFSLPG
RYRYARELIEDIKSSGDFCIGGACYPEGHPQAGSVQEDLEHLKEKVEAGCDFLTTQMFFD
NSIYYNFMYRLLRKNITVPVIPGIMPVTNGAQVKRILSLSGTMLPMRFRAIVERFADEPA
AMRQAGIAYATEQIIDLIANGVNHVHIYTMNKPDVAGAIFANLSEIYKRR
>A0A6M0YGK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MNIKNLFRDKKVVFSFEIFPPKITSSIQTIYNTLDDLKGLNPDYISVTYGAGGSVKNNKT
IELTSLIKNKYGIEAVSHLTCISSTKNDIEYYLREFEKNNIENILALRGDVPIGSKITGE
LNHANELIKHISDNGQFNIAAACYPEGHIEHKGLYREIESMKRKEEAGASYFISQLFFDN
NLYYNFQDEVRAANINLPIEAGIMPVTNKKQIERILSLSGASLPDKFKRIMERYEYNPEA
LRDAGIAYAVEQIVDLISTGVDGIHLYVMNNPYVAKRISQSIENILLTVNQNQFV
>A0A5C0WET2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus safensis|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSIEEIKR
SFREQLYILLNEEPDGLLLETYYDIEEAKAVLQIARKETTLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPLLENSHLSVYPNSSLPSLEAGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHISAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKDAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMAKAGEDKAKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKESNIHVNYH
>A0A7X4ABA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0666_bin_27|TrEMBL
MTPRTLQHTLAQGQFAVTVELNPPKGTDVSELLETAKSLSGRVHGINVPDNAAAVLRASP
VAVARLLYEQGHDPVLQLTCRDRNRLGLQSDLLGAHVLGIRNVLCLTGDSPGAGDHKDAK
PVFDLNTVQLMHAVQELNEGRDLAGNALEGRTAFFIGGAAAPGGEPTELLHKKFEAKVNA
GAEFFQTQPVFSAKVIQPFMEAVRPYSRKVLAGVLVLRSIKMAEYVNAHVPGIDVPDEIL
QELRNAGDAHVSEAGIEIAVRTIRAVRPFCNGVHLMAGRLAHRLPEIIRKAELN
>A0A4R3L848|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hazenella coriacea|TrEMBL
MEKSLKKHLQNSLLVGDGAMATYLYQQGAPVGHCTEEIVLSNPKLIAQVHLEYYQAGARL
IETHTYGANRERLTRYGLENKVTRLNREAVHVARQSVPNDAFVVGTIGSICAGRVSHYDE
DLYGDLYEEQAIALLHAGVDGLLLETFLDLKEALIAVDVIRPLTDLPIILQLSMIGVGRT
RDAYTLSEAFQLLAEHGVDGIGLNCRQGPVEMLRNLEKVIVPENLLLSAFPNAGRLGMNE
GKLNYPSSPLHFKETAQLLVDQGIRLIGGCCGTTPAHIANLSEAIQSLTPVNRVNPAEDV
WKTTHHPPIQVKRSRPTIVEKVKKERTIICEWDPPRDLDISQFLLGAERLHQVGVDSITM
ADNSLATARMSNLALGAIVKSQLGVDPLLHVACRDRNLLGQQSHLMGLHALGIDQILVIT
GDPTRMGDLPGANSIYDVTSIEFIHMVKELNKGISFSGKNLNQSAQFVVGAAFNPHVRQM
EAAVQRLSKKVEAGADFVMTQPVYDSKKLIEVYEATKEIEIPTFIGVMPLTGERNALYLH
NEVPGIKIPQEVLQRMEHKHGEEGRKEGIIIAKELLDLAMEKFHGIYLITPFSFYEMTEE
LTQYIRQKDQKRMKEVI
>A0A5P5Z976|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus rhamnosus|TrEMBL
MKISQCFKDHQVISFEVFPPRKNATNIAMRPILNTLDAVKAADPDFVSVTFGASGNKPHM
GTLEVAKLIKNEFNLEPVAHLPAAQLTRAQVDAELRGFQEAGIDNILALRGDIPKSGRVS
EDFPYACNLIEHIHQVGDFDVVGACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYQFRERAALAGINVPIEAGIMPVINEHQIERMATMAGVHLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIATATQTIRNA
>A0A5K8A9S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina ovata subsp. ovata|TrEMBL
MLRVFQNDISDPQQFVVTLELVPGRASTGRAVDTVMGIARDAFSDGRISAVSITDNPGGN
PSLSPDAIGYRIFSIGMDVIVHFTCRDMNRVGMESRALQLAMMGMKNILALTGDYAGKGF
GGQGAPVFDLDSVNLQIMLGMIGKRINAAGDPDAFFTGCAVSPFKKTEGECVAQYAKLSR
KVAAGAQFVITQLGYDARKFQELIEIGRHMDLGVPALGSVYVLTPKAAELMNQGRVPGAV
VTDPLLATVRQEWQDKTAGQAAAIERAARLGAILKGLGYRGVHLGGIHRDFSTVGKILDR
MQTIQDDWIQFLPEFNDPQPGGFYAFREAPPEPVTALVFGQQRQPVPIVDRVLYPLMRFS
HHLFFNFDSKLAPAYRLASHALDNSIAGRLFMHLGEHPIKLSLLGCQRCGDCAIQHVGFL
CPESGCPKHTRNGACGGSRGGMCEVYPDRRCVWFRAHTRLASNNKVSEMCHGCVPPRMWE
LNHTSSWLNFHLRRDHQSNGGEISGCCRQTTCHLLLGNTKERKDQP
>A0A841K171|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Silvibacterium bohemicum|TrEMBL
MTDRIRAMFGERTILCDGAMGTTLYARGVFINRCYDELNLSQPDLIRSVHDEYLQAGAEV
IETNTFGANSFRLLRYGLQDQVFDINKAGAQIARQAVEQLADKQAGKAWVAGAIGPLGVH
LEPLGKTGLDEARAAFAEQVRGLKAGGVDLLVIETIVALNEAEQAIKAAKEVAPELPILA
MITVDEESNCLDGASPEVAAARLTAWGADIVGTNCSTGPATILTTLEKLAAATSLPLAAM
PNAGMPRAVDGRNIYLCSPEYMANFARKFLKAGAQFIGGCCGTTPNHIRAMKSALRAVDA
QKVSAHGTAKVSLVSETPPPPIEQRSKIGKLIHEGTFVTMVEIVPPRGIDCKKELEGAAL
LAARGIHAINVPDSPRASARMSGQSLCIQIQQSIGVETILHYTCRDRNVLSIQSDLLGAS
SLGLKNILCLTGDPPKLGNYPDATAVFDVDAIGLTNIVQRLNHGLDIGGNSIGASTGFTI
AVAANPGVPDIDNEVRRFAYKVEAGAEYAITQPVFDLRILEAFLKRIESFRIPVVAGIWP
LTSLRNAEFMKNDLRVSVPDSILLRMQQASTPDLARAEGVKIAQEMLAAAIPMVQGVQVS
APFGRYALAAEVIADVLPKQQNAATANPTVAGASVTVATTEVSGAAVGNV
>A0A7U9R3E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MTTSRKSIPISFEVFPPKKDGEFQTAFATLDKLGALAPAFISVTYGAGGSNSGKTVEIAS
YIQNRLHLPALAHITCVGSKREALREVLAALKEAGVTHVLALRGDRPRDMTDEQFAARDF
EHASDMIAYLKELDPELHISAACYPEKHYECFSMQSDLGYLKLKQDAGAGDLISQMFFDN
DYFYEFLEKARRKGVTLPIHAGIMPVTSASQLGTSISLSGATIPKAFADMIARYGDSPED
MRKAGIDYAIRQIIDLKQNGVDGIHIYTMNKPKMAAEIMEAIRPL
>A0A7U6KHJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium KM106-2|TrEMBL
MNFREYIKNHFVITDGAMGTYYSRLTLSDNTVSEFANISDPDLIAKIHREYILAGASLIR
TNTFAANTQALNITEAEQEKLLRSACKIASNVAKEFDQEVYLAGSIGPIPENQEVERDEI
LNEYKRMCDILIEEKVDVILFETFSDYTYIEQLVPYIRSKSDVFLMANFCLDKNGYTKAG
ISLKRIFATLSEIEELDACGLNCGVGSGHMLEILSKESIPKNKYIAAIPNAGYPERLQNR
MVFFDNANYFKENMEKIQRLGIHIIGGCCGTTPTYIRKLRKEGSFVTCEQPDKNIVSMQK
VNIVKTAVNNTFYNKLMSGEKVVAVELDPPYDANYEKLMEQALTVKNSGADIITMADSPM
GRSRVDSILMSVKLHNQIGVEVMPHISCRDKNMIGMRSGLLGAYINDVRNLLLVTGDPVP
SDSRMSTSNVFDYNSIRLMEFTKEMNEEHFNGNPFIYGGALNYGRGRVDKVMERMEKKIA
AGATYFLTQPVYSEEDIERLRFIRSKLDTKILIGIMPFVSYRNANFIKNEMTGIFVPDDI
VARYHPDMSKEEAEWVGANLASEIIEKVQDFADGYYFMLPFNRVSMLEKIRIQ
>A0A3L7DP62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. SBT000027|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A3N0CNX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmoricola ginsengisoli|TrEMBL
MVTGQPTSIATLLAAGERSFSFEFFPPKDAAGEEVLWRSLGELESLKPTFVSVTYGAGGS
TRDRTIEITGRIARETTMTPMAHLTCVGHTVDELGDILDSLSAAGVRNVLALRGDPPGGP
GTEWIRTDGGVDYAADLVSLVRARDEFSIGVAVFPEGHRDSTSLDADVAVMKAKHDAGAE
FGVTEMVLRASDYFGLVERCRAAGVDMPIIPGIMPILAIGSMKKMVELSGREMPDEVLAR
IEPLAEDPEAVRAEGIRIATELCDDLLAGGAPGLHFYTLNRSKATREIYAALAVNA
>A0A1F5A7B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium RBG_16_63_14|TrEMBL
MDKIFHVELQTPKRSSEDIEKDLRVFEEKYRKVVEAGWIVCITDNPMGLLSYGAMETIDL
LGLPVHPDQLMVHLNTFHPKKELDEILGAVKAAGGKYLLIVSGDGSQKLHRLEPAEIGVE
AVTVTSVELLRYIDREYPGRFICGVAFNPYEPQDSELEKMKRKADAGASFIITQPIIGRD
ERLSGLAPFRLPVTLDAWMSKKLHLLSECVGHEIPEGTPYDPMENLKELRRNYPDYGLYL
AILGFKTQYPLLPEIWK
>A0A1M7P9F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclobacterium lianum|TrEMBL
MKVTEHIKAADKTLFSFEILPPLKGQSLTNLIEGIAPLMEFNPPFIDVTYHREEYVYKKH
ANGLLEKVSTRKRPGTVGICAAIMNRFKTDAVPHLLCGGFSKEETENALIDLYFIGVENV
LALRGDAPKTDANFVPHKEGHRYASGLVEQIIGMNHGRYLHDETEVGFQTDFCVGVAGYP
EKHFEAPSISYDLKKLKAKVDAGASYVVTQMFFDNRKYFEFVEKVREMGIDIPIIPGLKP
ITTLSQIVNLPRIFYLDLPDDLLLALERCKSNAEVKEVGIAWSIQQSKELIAYGVPSLHY
YTMSRADATYKVAKEVF
>A0A351XJT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
LKPDFISVTYGAGGGTSRHTVDIAKDIKDAYGVSSMAHLTCVSSTRETVKKQIMDMKAAG
IENILALRGDIPDETEFPLPGQFHYAAELVNEIKHIAPDMCIGGA
>A0A1G3ER28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium RIFCSPLOWO2_02_FULL_63_210|TrEMBL
MSQERRYSFEFFPAKTEAGHEKLLNTARQLAAYQPDFFSCTYGAGGSTRDRTLNTVLQLN
NDVGVSTAPHLSCVGDSKVELRELLNTYKDAGIERIVALRGDLPSGMGMASGELRYANEL
VSFIREETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGASSAITQYFFNADSYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSDSIRAYG
EQVISEMCERLLQGGAPGLHFYSMNLAEPSLAIWNNLKLPR
>A0A1S2PSN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces monashensis|TrEMBL
MPAVGAALLDDFSLEMTAKDVSRLEEARDGIPPGTRINITFLAGEDLGMRRAAARAVKRL
GFVPVPHISARRLPSRGALDAFLSALAEDGTAENVFVVGGDPARPEGPYEDSLAVLRTGL
LQHHGVRHVGISGYPEGHPAIADGTLWSALTDKAAVIGAQRLGGDVITQFGFDADPVLTW
LEATRARGVHLPVRIGVPGPAGVRRLLGYATRFGVATSASVARKYGFSLTNLMGTTGPDR
FLHTLARRYDPERHGTVKVHFYTFGGLRHTAQWITAFRHGEGTGSERRTP
>A0A378W7G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium senegalense|TrEMBL
MAPVYQRMSGLRAALDEKRFVVTAELGPPRGADGRDITRKADLLRDCVDAVNVTDNQGAR
VRMSSLGGAVLAQRAGLSPVMQLTCRDRNRMALQSDLLAAGALGIPHVLLLTGDHPRAGD
HPDAKPVFDLDGVQLTGLARTLRDEGVLASGDALTDRPRWMIGTVENPFAPPLSLRAERL
AKKVAAGAEFVQTQYVFDISVFTQWMKVLTDRGITERCAVLAGVGPVRSLRMLSFLRSSV
PGVSVPGEVERRLRGVPADRVGDEGMRLCAETIQQVAQIPGVAGVHVMAFGFERGVAEIV
QRAGLDHRATAGPTNSEGDRHVG
>A0A3B0A9E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora costi|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTPEGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPEGVLYAEELVRLIRDAGDFSVGVAAFPYKHPRSPDVATDTAHFVR
KCRAGAEFAITQMFFDAEDYLRLRDRVAASGCDTPILAGVMPVTQMGTIERSVQLSGAPF
PPALAERFARVAHDPEAVRRLGIEQASEMCGRLLDEGVPGIHFITLNRSTATREVWQNLR
VDARM
>A0A0S9QJC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Leaf288|TrEMBL
MVSSTSSGLSAAARLVAGYSIEMTGADVPALLAARDLIPANTLVNITFLSNETSEARVEA
ARTVIECGLTPVPHIAARRLRSTNELNEILAALQEVGATERLFLIGGDPASAIGPFDSSA
DIIESGVLSSFGVKQVGIAGYPEGHPAIPQDALWLALLHKSQLLREQGLEPNVVTQFAFD
VEPVVKWIGLARQKGLEAGIRIGTPGPAGVKRLLSFARRFGVASNATIVRKYGFSLSNLL
GNAGPDRFVSDLAARLQTELPSEQVKLHFYAFGGLGATASWAKQFVAEDASEERS
>A0A1F5U3E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Firestonebacteria bacterium RIFOXYA2_FULL_40_8|TrEMBL
MRFTELTKMGRFVVTSELGPPKGFHIEKALHEAEVVWPHVHAINVTDNQSSVMRLGGLAM
CKILKEKNIEPVFQVTCRDRNRLALQSDILSAALFGIDNLLLLTGDHTTLGDHKDAKPVF
DLDSVSLAYMVKQLEEGRDLAGNPLDGEPPKFCKGAVVSPCAEPLDPQLFKMEKKIKAGI
EFFQTQAVYEIDKVEKFMKKVK
>A0A8H3WI67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum asianum|TrEMBL
MHIKAMLDETRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREHEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDADNFIRWVGKVRERGITIPIIPGIMPIATYASFLRRAKHMNCRVPDDWMAAL
EPVKNDDVAVREIGKGLVANMCRKIIAAGIHHLHFYTMNLAQATRMVLEELDYMPSSERP
LKHALPWKQSLGLGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSIKDVANIFVRYLETEIDNLPWSEAPLTSEADGIREELIG
LNKRGLLTINSQPAVDGVKSSHPVHGWGPPNGYVYQKAYLELLVHPDLFPEIVARIEKNP
DMTYYATTKNGALTYNASSDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGTDW
ARCFEAGTPSRVLIDRIMNEWYLINIVNNDFHQKTALFDLLDGLSVQEYTDIPSEPKANG
ETELQNGTTGAAVTA
>A0A1F3CJ75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium RBG_16_67_12|TrEMBL
MTLREALASGTFVVTVEAAPPKGTAVADVLAEAEKLRGRVHAFNVTDQQSSVMRLGSLAM
CHLLAERGLEPVYQATCRDRNRIALQSDLLSAAALGIENVLCLTGDHVSLGDHPTAKPVF
DLDAVTLLAAARALTQGHDLAGKELTGTPAFFLGAVVSPCADPVEPQIFKMEKKVRAGAE
FFQTQAIFDLDRYAAFQEATRDIGVPLLAGVVMLKSAKMARFMNQNIPGIYVPDALINEM
EAAKDAKERERVSVEITARLIRGLRGVTAGVHIMAMGWDHLIPRVLEASGLQQPVEAA
>A0A269ZJ97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus kefiranofaciens|TrEMBL
MSLTALFKNKTVFSLEVVPPKKDSPKEAILPTLQQLQSINPDFISVTLGAGGSDHYTGTV
QIADLIQNQLNIPAVAHVPGLYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDF
NHANDLVAFVHQNRPDFSIASACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDN
QAFYDFQEKAEIAGIHVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSKEA
MREAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIA
>A0A3N1RXL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 840.1|TrEMBL
MVRSAGRKPTIEEIVRASSIEIIPLKGAEGKAAAVPAGTTISITCSPKFGLSRTLDHVAA
ARRSGLRVVPHLAARMVAGRAQLREFVSGVTDLGVDELFVVGGDGEEPVGPYSEALDVLR
ELREFDHGLTRLGVGCYPEGHPKIGEDELSEALALKQHYADYMVSQLCFDASALTSWVRS
ARDRGITLPLRIGVAAPLQARKLIELSVRIGVGQSVRYLSGQHGMVGSLLLGRSYEPMDL
LRAVQQEISFAEMSVEGLHLFSFNQVDAALEWISRATGTEQADKAG
>A0A085F4J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp. LC5|TrEMBL
MIDDNARASRKIAGQRPDLQLSFEFFPPKTDAMEERFWDSIHKLAPLQPRFVSVTYGAGG
STRERTLRMVSSVKTDTGVDAAAHLTCVGSTRDEVDTVVRGYQEAGINRIVALRGDPPEG
VGQPFTPHPQGYQNAADLVAGIRKIGDFDISVAAYPEKHPQSADWQADIDNLKRKLDAGA
NRAITQMFFSNADYLRYVDRARAAGITAPIVPGIQPIHSFKQISNFASRCGASIPAWLAE
RFAGLDEDPETHALVASAVAAEQVIELLDEGVTEFHIYTMNRSNLALALARILGRRPD
>A0A1P8WB28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fuerstiella marisgermanici|TrEMBL
MRLPEVFSSNPFAVSIEIFPPKTPEGDDALRKHLKTLVQHQPAFVSCTYGAGGSTQDRTV
SWCQEIKSDFDRPAMAHFTCVGSTRDQLNEWLDQAAAAGIENIMALRGDPPKGEESFQAV
DGGLQYANQLVQLIQDHPKDFAIGVAGYPEKHLEAPSMEVDMANLKRKVDAGADAVFTQL
FFDNDNFFRFRDSCAAAGITVPIVPGIMPITDFARIKRITSMCGTVFPEALATRLEAVQD
DADAQFEIGVGYAIEQCTALRDNGARGIHFYALNKSQACQKILEALAG
>A0A446B285|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. JV241A|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYQAAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHIEIAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAYG
EEIITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A134ADA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptoniphilus coxii|TrEMBL
MLKWKLFIFDTMEVTVHIQDYFDHSHTKLSFEIFPPNERMTLKSVMAAASRMVGYEPDFM
SVTFKADGSGGDQTVQIAKAVDHIMGVPSIAHLTCSGIPKSELEDRLAELQEANIQNILV
LGGDSKRELGEYAYLPYAKDMVRYFKERGDFTIGCACFPEGNNPALSMEEELDYLKEKVD
AGADFLTTQMFFDNEVFYRFLDAARAKGIDVPILAGIMPITAAGQIRRIADLSGAKLPRT
LTDMVARFGDNKEAMFDAGVTFAEHQMADLAARGIDGVHVYTMNKPAIPERIVNDIGSLF
R
>A0A511JQ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas terrae|TrEMBL
MSNVPKVTCPRTAPVPGGPVGRAVSAAAVDSRTPGLHAATSRRAVAANDRPTISFELFPP
RNPDAAPRLWATIRELETVQPDFVSVTYGASGKTRVTTRALVRRLLRETSLNPIAHLTCV
GTSREEITTIVGEFLDEGLRSFLALRGDPPTDQSDWEAHPDGLQTAGELVELLREIEAQR
CADSPSQAVRARVRPLSVAVAAFPRGNHATGGTRAQDVASLLAKQEAGADFAITQVFFDA
DDYLGIVAEAREAGVTIPIIPGIIPTTDPARLLRVQELTGVPVPHDLLDLLGSADDDLDR
HRRGIRASVDLVNGVLDGGAPGVHLYTFNQHHAALDLLEGAHLDGGARTAPDLASWPQDT
APARSTRD
>G8ZXU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Torulaspora delbrueckii (strain ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866)|TrEMBL
MKVSEKLQKHKEVSTKATFSYEYFVPKTTQGVQNLYDRMDRMYESSLPQFIDITWNAGGG
VLSQLSTDLVATAQSVLGLETCMHLTCTNMPVSEIDDALQKAYDSGCQNILALRGDPPVD
SNEWTPVEGGFRYAKDLVKYIKAKYGDHFDIGVAGYPEGHPEDDTDDSKLIDYLKQKVDA
GASFLITQMFYDADIFIAWCKKVRAAGIEIPIIPGIMPITTYAAFLRRAQWCDIHLPQEF
LDRLEPIKDDDQQVRDTGTDLLVEMCQKILDSGYVTHLHLYTMNLEKAPLMILDRLGLLS
QEEHVNGENSLAMLPWRKSLNPQRRNEEVRPIFWQRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSSLIRQSGKKSLELWSTPKTVEDVAQLVVNFLERKVSCLPWSDTALN
HEVDVILNDLIDLNKKTIITINSQAQVNGIKSSDPIFGWGPKDGYVYQKQYLEFLLPKSK
LPKLHDALNSDAILTYFAVDNAGNLTSNHPDGNKANAVTWGIFPGREVLQPTIVEKISFL
AWKEEFFHILKEWRLNFQNHQIKESIDVLNDLIDNYVLVNIVDNDYVSQENKIFALLNNI
>W1S870|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. C100|TrEMBL
MTLNDPAAPLYADLAGDARVSFEFFPPKTEKMETQLWSAIETLTPLAPRFVSVTYGAGGS
TRERTHNTVARIARETPLAAAAHLTCVAASKDEIADIADAYWEAGVRHIVALRGDPPEQG
GAFEPHPQGYTGAADLVEGLVKRHPFEISVSAYPEVHPDAASAQSDLDNLKRKLDAGATR
AITQFFFSPEAYFRFLDKTAAAGITADIVPGIMPVSNFAATQRMAAMCNTQVPSWMARLF
HGLDDLPAARQLVSATIAAELCRQLYAGGVRDFHFYTLNRAELSYAICHLLGLRAQAAGN
DSEKAA
>A0A2E1CF01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVIEHIKNAKKTLFSFEILPPLKGKSIQSIYDSLDPLMEFNPPFIDVTYHREEYVYKKR
NDGLLERRSVRKRPGTVGICAAIMNKYNVDTVPHIICGGFNQEETENALIDLDFLGVENV
LVLRGDPIKNETYFTAEEGGHSYASELLQQIVAMNNGIYLDEELKNSSPTNFCVGVAGYP
EKHFEAPNMKSDIHFLKKKVEAGADYIVTQMFFDNQQYFDFVNLCRENNITIPIIPGLKP
ISTIKQLTLLPQRFHLNVPNALVDTVIKCKNNEEVRRVGIEWSIQQTKELIEFGAPCIHF
YTMGRSDNVQEIVANFC
>A0A4R0N4J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter frigiditerrae|TrEMBL
MKITDHIKNANGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADTSFVPTKGGHCYATDLIQHIKNHNEGKFLHEDIDTFKSDFCIGVAGYP
EKHFEAPNLNADFKFLKKKVDMGAEFIVTQMFFDNQKYFDFVNKCRENGINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPEDLTDALAHAKSNAEAKEIGTEAMIKQCKELIEFGAPVLHF
YTMGRPEQTKQIARAIF
>A0A0E2RCT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus thermophilus TH1477|TrEMBL
MTSQTPSLSFEVFPPNPAVGNKKILLALDDMKGSAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRELDAVGVNRILALRGDIIPGVEPLKDFRYATD
LIEFIKAEAPNFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIYAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETARHIYEATHSLFKHHSQVGAL
>A0A7M7G2U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nasonia vitripennis|TrEMBL
MYLRRVCRLASVGRVSRRSLDSSRGMRHRVLGDEEPQVDESESVLASATTLDPGPPVNLA
GLIREKIERRESFCSYELFPTKCHGVYQGFFRDTQICEPLFYALTWHEGWATGEERFPSL
KSAEVFPRNTLLHCTAKGLKKTDAEMILTRALELGIANIFALQGDSGSDDGDFDHASDLV
KFIRERYGQQFSICVAGYPEMHPHSPSKELDIFYLKAKVDAGADFILTQFFFESQLFIKF
VNDCREVGISVPIIPGIYPFTDVKLLGKMIEICHTNIPDWIQEELRHIEDDDEAVRKFGI
DLSVKLIKEIRESAHFCGYHVYTLNRSFSAIEVHRQLNTQHEIDQLVASNS
>A0A6M6BFP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp. TS19|TrEMBL
MKVTEHLTRADGKTLFSFEVLPPKKGENIQNLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGFLEKKTVRKRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFKPDPDGHAYAADLIGQVANLNKGEYLDEEQDDTWATNFCIGTAGY
PEKHFESPNYGADLRYLKHKVDRGAEYIVTQMFFDNEQFFNFEKRCRNAGITVPIIPGLK
PLTTKSQLTMLPRSFYLNLPEELADAVQLAPDNAAAREIGIEWCINQSKELMAHGVPCLH
YYSMGKSESIRRVAAALF
>A0A3C0D4S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp|TrEMBL
MLDVRKLLAQRPLLFDGGMGTYYKAKPGQECEQANLTDPEGILAVHRAYLAAGADAIKTN
TFSLPRLAAAQQPGWEQLADAGWQLAAKAAGETGAAVFADLGPAPDTENLPAAQVYLAVA
KRFALLGARNFLFETLSAENGVLEAIRALKQTVPEAFVLVSFAVLPDGYTREGRYCAELV
RRMAQSGVVDAVGLNCVSAPGAMRALVQQLGDAGLPLSVMPNAGYPVVARAQVRYQGKPE
YFARELSRLATEGVRILGGCCGTTPQHIAALRTALDALPETLPAAPAARPAATAKPAVET
DDAFLRKLRAGQRVIAVELDSPKDADLTAYLEGARRLQTAGADLLTVADCPIARARMDSS
LVACRVHRELGLNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPITVFGALNLNARNFEVELRRAAEKLENGMSGFL
TQPVLSAQAVENLKKARETLGERAKILAGILPVVSQRNAIFMENEVNGIHVDEAVIQKFE
GLDRAAGEELGLEVSVQAAKAAAPYADGFYLMTPFNRVALMERLIARLRTEVTD
>A0A2L0IAI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ACNIH1|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQRNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHKIAGIVITPHMLRVLAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVET
KKELVPQLAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A7R9P629|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Timema californicum|TrEMBL
MKHDPQRFTENLEAPGIKPRTFGTLTIRSQRQQYKGVRNIQSCQASFSAVTWHLETPYLL
KPREIPALQLATLLVNNKLVGPNSVLLHLSSVDAGANFIISQIVFNAVCFSQFVKDCRNI
DIAVPILPGVMPVQSYKSLERTSSICHIPIPRAILDAVKPIEDNDDAVRNYGIHQAVQTI
KEMFSLGCATGVHFFTLNRGTMVHEIWRQLGFMSTSPSRAITFNSSDEGNQEYEKKQCLN
I
>A0A521G5F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electronema sp. GS|TrEMBL
MKSGSNLERVLRSGQFAVTGELGPPKNSDPEVVRAKARLLKGKVDAVNITDCQTAIVRMS
SIGAGLLAQAEGVEPVIQMTCRDRNRIAMQSDILAASALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQMLGMMRDLRDAKKFQCGEELKGTAPQLFLGAAANPFAWPFEFRAVRMGKK
IANGADFIQTQIIYNVEKFAEFMKQARDLGLTEKAYILAGVTPPKSLGMANYMKKFVPGM
DVTDAVIERMKGAKNQKQEGINICVDIINQVKEIPGVAGVHVMAIEWEEAVGEICEKAGL
LPRPTFAEDAAAVQPVKESAAPVAETIEVRGAAADELLNQAKAEAEKIIAAARAEAEAIA
AARPQVGAEINPAAPAADDAGEHEMNEKERLLALDSVSVGLKALKAAYGLSDDQFEALMN
FARAEAVLKREPECCAKKPVAAAPVAPAAPVVDDSATKAAAEAKLKAEADAAAKAAAETE
AKEEAAAKAKAEAETKAKADAEAKLKAEAEAKAKAAAEAAAKVAAAVKPAPAAASADFAA
PALATGEAPFAERAAKVPASSYKVNYSGTIREVTLGNGGKTVTVGGSTSLPFHLFEGAMK
NKPLIAMEVMDIRPDNWPQTLSRHFEDVMSDPVAWARKCVDVYKADAINIWLAGTDPNGA
NRPAKDAAQDAAKVIQAIDVPVIVWGCGNADKDTETLREVTSMIGDKKVCLAPLEDSNYR
SIGATAMAFRYPVVAASPIDVNLAKQLNILLENLGVGLDTVLMDPSVGALGYGIEYTYSV
MERIRLAALTQKDEKLQVPLICNLGREVWKTKEAGLPSDAMMGDQERRGIMMEAVTASCM
LMAGGEVLIMRHPKAVNMTKSLINGLVG
>G2TR32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weizmannia coagulans 36D1|TrEMBL
MPPFLGGFFHIIQRECKNLNLLETLKNRILVADGAMGTLLYAYGADTCYESFNLTHPEDI
HAIHRAYIEAGASVIQTNTYSANYIKLAQYGLEEKVKDINKAAVQIAKEAANRDTFILGT
VGGIRGQRKTEATLAEIKRTFREQIFHLLNEGVDALLLETYFDAEELYTVVDIAKKEADV
PVIAQFSLIEPGVLQNGTPVRDAFKELENRGADVTGLNCRLGPHHMIQAFEEIPIPKRAF
LSAYPNASLLDYEEGRFTFTNNADYFKTCAEKLVEQGVRLIGGCCGTTPAHIKAIADGVQ
GLLPVTEKTVRPPKIEIAAAPAQHEPPLHEIVKKRRSVIVELDTPKTLNTARFFEGAKAL
HDAGIDALTMADNSLASPRISNTAIASILKEKHGIRPLVHITCRDRNLIGLQSHLMGLAA
LGIDQVLAITGDPTKIGDFPGATSVYDLSSMELIAMIKQFNDGISHSGKSLHRKTNFSVA
AAFNPNVRNLDKTVGRLERKIRHGADYFITQPVFSTEKIEQIHEATKHLDAPIYLGIMPL
TSYRNAVFLHNEVPGIKLTDEILAAMEKTNGDPAKAREESLAISRTLIDAALGYFNGIYL
ITPLERYELTVECTRYIHEKTAVQGAGIV
>A0A5N6YNJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus arachidicola|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGTT
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEARVLGIRNILALRGDPPRSEE
YNMHGEDDSNRDFTFAVDLVRYIRQKHGDYFCLGVAAYPEGHPVDSFQDVQDPKSDLPYL
VEKTQAGADFIMTQLTYDIEAYTRFENMLRTHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVQIPPQILSKLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLRGFHFYTLNLEKT
VSFILERCDLIPPYSEDFDAIEEGGDISAMDGAQLRSLTRRRASSINSLPHNRVIVDKLH
ASEVSSKASVSHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSS
GLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFF
CPSKDYHSILKPLLQKHGHEKLAWFAANIKGDFESSLPAQTSDADPIEMNPDNVNCVTWG
VFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNDVKDDVWLVCVVG
QEFGAGTELGSEEEEDEKKFMWRVLLNAKK
>A0A564U2Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea longicatena|TrEMBL
MKISDILVEETPHLSFEVFPPKTDAAYEGVLKATEAIAELKPSYMSVTYGAGGGTSKNTV
KIASHIKNKYGVTSLAHLTCVSSTKEEVHQVIDQLKTAGIENILALRGDIPKESEFPLPN
HYQYAYELIRDIKAQGDFCIGAACYPEGHVESEHKKDDIAHLKQKVDCGVDFLTTQMFFD
NNILYNFLYRAREKGVTVPVIPGIMPVTNASQVKRILSMSGTNLPERFKAIVDRFGDNPK
AMQQAGVAYATDQIIDLFANGINHVHVYSMNKPEVAAAIQANLSDILSK
>A0A5P8MY50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylobacter sp. TS-1|TrEMBL
MSSDVERRSRRAGGRPISVSFEFFPPKTPEMEATLWNSITRLAPLAPKFVSVTYGAGGST
RERTHTTVERIVKETRLAPAAHLTCVSATRGEVDEVVRGYWDAGVRHIVALRGDPPGGVG
QTYEPHGEGYRTTAELVAGIRRTANFEVSVSAYPEKHPESPSFETDLDILAAKVDAGATR
AITQCFFDNDLYFAFLDKVRARGIDVPIVPGILPVSNFKQARNFSEKTGTYMPDWLAARF
EGLDNDPETRKLIAAAVAAEQVFDLVDRGVTEFHFYTLNRADLVYAICHLLGIRPPQEAG
QGEGKGQAAA
>A0A1S1D7Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC065H07|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHGATHSLFKHHSQVSAL
>A0A1B9GL69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kwoniella heveanensis BCC8398|TrEMBL
MTQLTSLISSHDGPFHTFEFFPPRTEAGLVNLLDRIGRLAAAPMPAPLAVSVTWGAGGST
ADKSLELAEQVVKLGVEVILHLTCTNMAKEKVDQALEKCRSLGITNILALRGDPPRSEEY
AVDPNPQPDFFQHADDLVRYIRKEYGDYFCIGVAGYPTPHSDSESAESDLHYLKVKCDAG
ADYIITQLFYDVEGFLEWVTTCRERGITQPIIPGIMPIQNFSSFRRLVNLTKCPVPESIT
ADLQPISSDDAAVKRYGAELATRMVRQVFQSGLVPGVHFCTLNLEKSVRTILENLGWSAT
SDPNLRASPFIRYNRLIEDDEPQTNGAIAINGHSDGSPKNQVKDLSISPSEASVLAQWGL
THHAPPPVPKRDSWDEYPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKEWGTPTNVNEL
AKFFVSYLESSPSTPTTPFCDLPLSSESIPILPHLIALNSEKIQHWTVGSQPAVDAANSE
DPVFGWGPRGGYVFQKAFVEFFVREEEVKRLEEKVEKKGDGLISMYAGNKKGDFRTNTEK
DAVNAVTWGVFPGQEIVQSTIIEAESFHAWKEEAFDIWTEWSLLCPRLSPSRRLLESIAG
EWWLVSLIHHDYKDPDALWKFLLEE
>A0A2R6KYY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon SW_12_69_24|TrEMBL
MVMRSDSTTRTDGVADLLSGARYELMPFESFDGELQYLPDEAVVAVTTSPTLGIEATVEK
TEAAAEVGYELAPHIAARYVEDRDHLDEILTRLSTVGVTDVFVPGGDREEPAGEFESAHD
LLSAMEELGHDFEEVGITGYPEGHEFLDEDTLATAMQRKEPHATYIVTQLCYDPTAVVDW
IDRVRDRGVGLPVEVGIPGVMNYQRLVQISRKVGVGDSIDFLRKTSSVVGFVKRLVGSRG
SYEPDDLVDGLAPYADEEAYGIRGLHVYTFNNSEATEGWRRRRLEG
>A0A809NBJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter cinaedi (strain PAGU611)|TrEMBL
MLDQLITKLKSNEPFLSVEVSPSLSFTIGQGVIDELESLSQADCFVCTDSPLARLKPSSI
LSSIKLQNALQKPVICTLSMRDRNSIALCGDILGANEFGLRSFLSLSGDGVKNGDCTGAK
GVFEESSLKLGRIIDGLNQGIAANGKVLKDSVETIYNFSVINSYANNTESLKKKMLKKLS
NSLVQGLFTQPVFSLESARFLLESMESINKELGQNCVMILGFFPVPSYKVALFLRDKLPG
VYIPDEWVQKLEKASIKGKEEERKIGLELSNKLFKDLQTLHNKFHFMSANKPSLLREFV
>A0A328VPT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermogemmatispora tikiterensis|TrEMBL
MEHVLLERLRQGPLLCDGAMGTLLYARGIPYEQCFDLLNVTRPELIQGIHREYISAGAQI
IETNTFGANRLRLAAYNLEDRVREINFQGVRRAIEAREIVGLPVFIAGAVGPSGQPLQAP
ESGRLSEVRAAFREQIEALQEGGAELLILETFTSLAELRQAILAAQEVGGLPIVAQVSFY
EDGRTLSGQSAASVARELYELGVDVMGANCCVGPAMTLEALQGMIGALDEEIQAAAQQGK
RPPLFSAQPNAGLPTRLGNRFFYVSTPDYFADYALRFAQAGVRLIGGCCGTTPRHIEAMR
KALDAHYGRGTGAVGQKDEAGQQNGLSASAQGQEGSRTASAVLPGRGGRRPAIGTLPEEE
VILPQEGSKTRLQQKLEAGEFVISVELDPPMGLNPSKILAGAAQLQRDGVDCINIADSPL
ARVRMSCIALARLIQDHLGMETIIHFTTRDRNLMALQAELLGAHALGLRNILALTGDPLR
VGDYPNTTGVWDVDSVGLIRILRGMNEGHDAAGGSIGAKASFHIGAALNLNVSEEEAERE
IEKYYRKLEAGAHFIMTQPIYELAPLERFLKRVGKPPVPVILGCIPLHSWRHAEFLHNEV
AGVTIPERVRERMRAAGDQGTEEGLRLAQELLMEARDLVQGVYLLPSYRRYDIVGRLTRL
LREAPANA
>A0A8H3GGI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
IYSIRVFFFFLSFFLQEAKANGCRNILALRGDPPSGQEEWTSVEGGFQHGVDLVRHIRRE
YDDYFDVSVAGFPQTIQLPEAEAKQEMQWLKEKCEAGANFIFTQMFYDADMFIRWVKAAR
EAGITVPIVPGINPIQTWNGFIRATSLSGTDIPQDLMDILEPHKNNDEKVRELGTKIVAD
LCRKILDADIGIRGLHFYTMNLEKGTKMLLEELNLVPRVETIKPLPWRQSLTPTRRTETI
RPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELDGYGIWIKQTPEEGRKIWGTPT
TMDDIKDLFTKFCSQQIKALPWSDQPPTTEMLVIGQQLARMNELGYLTINSQPAVNGARS
DDKAFGWGPKNGYVYQKAYLEFFVHPAQLQALIKRIERDTNVTYYAINKQGDLKTNSTSE
GPTAVTWGVFPGKEVVQPTIVEAVSFMAWKDEAFELGCQWAKIYESGSPSRKLIEGMMDE
YFLVNFVHNDFHDREAIFRPFFADTGLKANGNSETPAVNGVKHANGLVNGHSTAVHA
>A0A8C6XJN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naja naja|TrEMBL
MVNESHGEFLPMSNGLGTRSDGGNSSSSGESSQNSSRCSTPVLDTERHERLREKMRRRQE
SGDKWFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMMAT
TALNYCGLETILHMTCCNQSRESITAHLQKAKRLGLKNIMALRGDPVGEEWEEELDGFNH
AVDLVKHIRKEFNDYFDLCVAGYPGGHPEADSYNDDLKHLKEKVSAGADFVITQLFFRTE
TFLKFLKDCQAIGISCPVVPGIFPIQGYHSLRQLVKLSKLVVPQEIKDVIEPIKDNDAAI
RNYGIELAVKMCRELLESGLVHGLHFYTLNREVATMEILRQLGLWNEDPRRPLPWAVSAH
PKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSAR
EELLKMWGEELTREESVYEVFRCYIAGEANRNGHKVSIREKHGPFLVKGEERWTLAMEKA
KPKLTTLIECSFSSNVSQPGVGFYQFAPIP
>A0A1F8RCX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_60_22|TrEMBL
MASRFKQALDSGKFVITSEVAPPKGTNLEKMFHHIELLKDKVDGINITDHQSSVMRYPSL
GGCLAVSERGGEPIMQMTCRDRNRMALEADLLLAYSRGIRNVLCLTGDAVPVGDHKEAKG
VFDLDSLQLLRAIRQLTEGKDLGGNELDGAVEFCMGAIVTPEAQPIEPQLIKFEKKVEAG
AEFFQTQAIYDLENFKKFMEYARKFKAKILAGIVLLSSARMAKYMTQNVPGIFVPQALID
EMSAVPKEEMLAKGIEIAGRAIAALKKDKICDGVHIMAIGKEEVVPDILEAAGL
>A0A0E1UUX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei Pakistan 9|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A4V0YDS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium protaetiae|TrEMBL
MTGKDVPGLEEAAQAIPAGTKINVTFLGNEDLEMRVAAAKRVKELGFTPVPHISARRIAS
QAQLEEFLSALHGVGATDHIFCVGGDPATPEGPYADSLSVIRSGILPDYGVKEVSIAGYP
EGHPDIPTDVLWQHLGDKSAALTAQGLDAVILTQFAFDTDPVTAWIDQVRSRGIDTQIRI
GTPGPAGIKRLLGFARRFGIGANAMIVKKYGFSLTNLMGTAGPDRFVTDLSALLAQDPAS
GSVKLHFYTFGGLLATANWARGFVAERA
>A0A4Y4KE88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 6-11-2|TrEMBL
MALGTASTRTDRARTVRDMLATGKSTYSFEFWAPKTAKGERSLWNALRRIEAVAPDFVSV
TYGAGGSTRAGTVRATEQIVSDTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFDPESYLRLRDRVAAAGCATPVIPEIMPVTSVKMLERLPQLSNAAI
PDDLKERIRAAEHDPAAVRSLGIEFATEFCARLQAEGVPGLHFITLNNSTATLEIYENLG
LHHRPRT
>A0A4R7LBU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypnocyclicus thermotrophus|TrEMBL
MKIKDIYMQKKESKKPVFSFEIFPPNSKHPIDTIYNTIDELSKFNPDFISVTYGAGGSTR
GRTVEIASRIKNKYNIESLAHLTCIEAKKNEIDDILYKLKENNIENILALRGDHPIDREP
IKGDFNYASDLITYIKNKNMDFSLGGAYYPEGHFETNDLMDLFNLKRKVDLGAEFLISQI
FLDNEILYRFKEKTDKLGINVPFAAGIIPVTNAKQMKRIFSLSHCSISPKFKRILDKYEH
NPEALKEAGIAYATEQIIDLVAWGIDGIHLYTMNKIDTTRKIVKDIEYIIK
>A0A136LJX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium OLB12|TrEMBL
MEFKPPFIDVTYHREEYVFKKKEGGLLEKITTRKRPGTVGICAAIQNHYKVDTVPHIICG
GFSKEETENALIDLNFLGVDNVLVLQGDAIKTESKFIPEKDGFAYASELLEHVVNMNRGQ
YLDEELHEPSPTNFCIGVAGYPEKHFNAPNLKTDLKYLKNKVDKGAEYIVTQMFFDNKKY
FEFVDKCREAGITVPIIPGIKPLTTKSQLTILPQIFHIDLPEELTEAAEKCKDNTAIKQV
GIEWAVQQSKELIQKGAPTIHFYSMGKSDPIYRIAKELF
>A0A2D9SFL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MNNNFKKKLDDNKFVFTAETSPPLSANKDDVLKRVLCLKDIADAVNVTDGASAKSHLSSL
VVSSILSSNGIEPIWQLTTRDRNRIAIQSDLLGGWALDIKNILCIYGDQVSSGDQPEAKE
VXDLDSIGVIKTAHQFKTQNTLPSGREILSSPEYFIGAADSPFEIDKDFDCKNLLXKINS
GTNFFQTQFAFDYKVLANYMKRLNDFDITNKAYYLVGLGVLKSAKSAVWMNNNLFGVXIP
DNIIKRLENSADQEKEGIKICIELVEMYREIEGIHGVHLMGYHQEEQIAEVISNF
>A0A657BE51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleiphilus sp. HI0079|TrEMBL
METQKQFKRRFSFEFFPPKTEEGKEKLQVVRDELARRKPDFFSVTYGAGGSTQERTIDTV
LHFQDQGISTAPHLSCVGSSKEEIAKLLDLYKERAVNRIVALRGDLPSGMGGSTGELKYA
NELVAFIREHSGDHFNIEVAAYPEFHPQAPSAEVDLENFKRKVDAGASSAITQYFYNPDA
YFYFIDRVEAMGINIPIVPGIMPITNYSNLMRFSDMCGAEIPRWIRKQLEAYGDDKASIV
KFGEEVVTQMCDTLLAAGVPGIHFYSMNQAEPSLKIWDNLGLSDNEKIKF
>A0A5D3FJR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura decatromicini|TrEMBL
MPRLRPERPPTVRELLASGGRSFSFEFFPPKTDKGARNLWRAIRELESLHPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVRHPEGVEYAADLVRMIRSYGDFCVGVAAFPYKHPRSADIESDTRYFVEKCRA
GADYAITQMFFRADDYFRLRDRVAAAGCDVPILPGIMPVTQLSTIERSEQLSGAPFPAEV
RARFEAVGDDPEAVRRLGIEHAAELCRELLDQDAPGIHFITFNKSTATREVYSLVDGAGY
GARGSVPPMTA
>A0A212JLG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Dysgonomonas sp|TrEMBL
MTITELINKSDKTAFSFEILPPLKGNNVEKVYNIIDKLIEFDPQYINITTHHSEYLDQQM
PDGTVKRVNIRKRPGSVAIAASIQHKYNVTAVPHMICKGFSQEETEYALIDLNFLHVQNL
LLLRGDTKRLAPEQIYPNRNEYATDLQLQVNNFNEGIAADGSLFEKNATPFSYGMACYPE
VHEDAVSAESDIFYMKQKADNGAEYFVTQMFFDNQKYFSFVEKCREAGITQPIIPGVKPI
VLMSQLEVLPRIFRSSIPEELAVELRKCKTDDDAKEVGIEWGIKQSKELIEYGVPSIHFY
SLLATESVRRIAKEIY
>A0A1B9K436|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNQLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHAVKYTYGIESVAHLPGINFSKVEMQKILADLKSAGIDNVLALRGDISPNVEPKNDF
RFASELVTFIKENGGFNIIGACYPEGHLEALTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFFAFLDKAHDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQIMEKYEHHPDAF
RDAGIAYAIDQIVDLISQNVDGIHLYTMNNSYIARRINEAVSTLLEIPKA
>A0A7C1SVJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKSGSNLEKILKAGHFAFTGELGPPRGTSAEEVRKKAAHLKGKVDAVNITDNQTAVVRMA
SWAACIILIQEGLEPNYQMVCRDRNRLAMQADILGAYAHGIRNMLCLSGDHCKFGDHPHA
KGVFDIDSMQLIQMVKKMRDEGKFLSGGELEEPPKIFIGAAANPFADPFEWRVHRLAKKI
KAGVDFIQTQCIYNMEKFQEWIKQSNEMGLTEKVYILAGVTPMKSVGMARYMKNNVPGMD
VPDEIINRLKGVDKKKQGDEGIKIACEQIEKFKEMKGVSGVHLMAIEWEHKVPEITERAK
VLPRPQVD
>A0A1Y1I609|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsormidium nitens|TrEMBL
MTKIIDKIKQQDGKVAFSFEFFPPRTEEGVENLYERMDRMAAHQPLFCDITWGAGGTTAD
LTLDIATKMQNMICVNTMMHLTCTNMPVEKIDEALEKVKAAGIQNILALRGDPPKGQDKF
VAVEGGFASALDLVKYIRLHYGDYFGITVAGYPECHPDYIEGPGGASEQAYKENLAYLKS
KMDAGGEVIVTQLFYDTDVFLKFVKDCREYGIDAPIVPGIMPINNYSGFKRMTAFCKTKV
PQHILDALEPIKDNDEAVKAYGIHLGTEMCKTLIAGGTKHLHLYTLNLEKTVMAILTNLG
LIDESKVQRTLPWRPPTNIKRRGEEVRPIFWANRPRSYLSRSSNWDEFPKGRWGDSRSPA
YGTLNDYQFLRKKSKDLKLREEWGIDLKSSEDVFKLFARYCKGELSAFPWSELETLQPES
QLITDRLTSLNERGFLTINSQPAVNAEPSDTPGIGWGRPGGYIYQKAYVEFFTSPERLQA
IISKMPGFPSLTYIAVNVKGETYSNIGVTDVNAVTWGVFPAKEVIQPTVVDPQSFMVWKD
EAFDIWTSEWASIYPDDSPAKKVLQETHDGYFLVSIVDNDYIRGDLFAIFEGL
>A0A6M1T6M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliifodinibius halophilus|TrEMBL
MKVIEHYDQADEPLISFEIIPPKRGGSVKKVFESLDKVMKYNPPFIDVTYHAAESYYEEL
SDGTIKRHVKRKRPGTIGLCAAIKHKYGVDPVPHLICEGFTKEETEDALIELNFLGIDNV
LAIRGDAQENATPRLKNGTFNKYAIDLVNQIKDMNRGKYLEDIVNAHETNFCVGVAGYPE
KHFEAPNLDFDIEQLKKKVDAGGDYIVTQMFFDNEAYFRFVDKCRDAGIKCPIVPGLKVL
TRERHLNFLPKFFHLNIPEALSDEVQADPENAREIGVEWAAQQCTELLEGGVPGIHFYIM
GDPTPALDAVDQLPLGHDVVKR
>A0A8J6LPQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Longispora sp|TrEMBL
MPSNNGSIRQERPASIGDLVRADAPTFSFEFFPPKDSDAERVLWQTIRELEQLRPSFVSV
TYGAGGTTRDTTVEVTERLATETTMLPMAHLTAVGHSMRELRNVIGRLVDAGIRNILAIR
GDPKGDPLGEWIQHPEGLLYAEELVELIKEAGDFCVGVAAFPHKHPRSSNIDEDTRYLVQ
KLRAGADFAITQMFFEAEDYLRLRDRVAASGCDAPIVPCVMPVTRMATIERSVALSGAPF
PPALAAKFEQVSGDPSAVRSLGIDQAGKLSEQLLAEGVPGIHFITFNRSTAAREVWLNIA
GKVKNAA
>U4R0X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminiclostridium papyrosolvens C7|TrEMBL
MNIFINRDYFLFDGAMGTYYSSKHKNNTPCEFANISERENILNIHLEYIQAGVNAIKTNT
FGANRFSLGCQQSEVDRIIKSGYDIAAQACSGQEVAVFADIGPIPDGKGANPEEEYKRIV
DIFMECGAKNFLFETFANTDVLTGVAAYIRLRLPDAVIVTSFAVYPDGYSKEGLFYIDIM
EKMYASGLVDAVGLNCISGPAHMYRLIEKADIRGKNIIIMPNSGYPGSERGRTVYSDNSE
YYAEKLVDIKKLGVKILGGCCGTTPRHIAAAAKLLSCPQPVESNAGISTHIETCDLANEN
ILDRIIKNKKPILVEVDPPFDTNWEYMLRDTLILKQAGADIITIADSPLAKARAESTIMA
AKIQREAAIPVMPHITCRDKNLLGIKASLLGGHIEGIRNVLVITGDPIANIERSRIKGVF
SFNSSNLANYIKSLNSNVFCGQDIKIAGALNVNAVNFSAELKKAFTKIENGISCFLTQAI
YTKSAVENLLKAIETLNVPIFAGFMPIVSYKNAQFINNEVPGIDIDTETIEKFRDRSREE
SEKLGMEITMDIVEEIYPHVSGFYLMTPLKRTGVICELIKKIKEI
>A0A7V5C621|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKLKEALGKKRFVVTSEVQAPMGDDNPEELVENLKRVRGRVDGVSVTEVELEGIVGDTIK
TCEILKDNRFDAIYQTTTRDKNRIQLQKDLSLAHDAGVENLLVFTEDYRITGDSLQETMF
FHVDSGKLASVLDHMREGQSVDGKELSGKMDFTMGTGVESSWGKNVPRQGMNEMETMREI
GAGYFLTTPIFDLDQFEKFMRQVGTFDVPVIAEVMILRTAGMARFLNRHFKSVLVPDWII
RKLDKAPDKQKASIELFTDTVNGLKDICQGVHIITIGGEEKLRQYLDAAKLR
>A0A7Z9WCV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MEPKTPSRLEKILAAGHLAVTAECGPPRGSNAQVMLKKALRMKDHVDAINVTDNQTGVTR
LCSLASVIHLKSVGLEPVLQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQGFGDCP
GAQNVFDIDSMQLISLVRHMRDNGCFISGDKIDRPPRMFVGAAANPFGDPFEIRVARLAK
KVKAGAEFIQTQCVFNLEKFLEWVKQVRDRGLHEKVYILAGLTPLKSVGMAKYMKDKVPG
IDIPEEIIRRMASVPKKRQAQEGIRICVETIERLKGEEGI
>A0A2E4Q6W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia sp|TrEMBL
MTSRLTIPDSPQLPPAERDGNIGHLERVLRSGQFAVTAELAPPDSADPQEVHARAQLFAG
HVDAMNATDGSGANCHMSSVAMCALLAREGHETVMQISCRDRNRIAIQGDVLGAAALGIR
NLLCLTGDGVQVGDHPEAKPVFDLDSLSLLEIVAGLRDKHAFASGRTLTSAPQVFLGAAA
NPFAPPFAFRPHRLAKKIAAGAQFIQTQYCFDLPRFQDFMHRARDLGLLEKCFILPGVGP
LASARTAEWMRRHVPGVHIPDDVLKRLKGARDQKAEGRDICIEMIQQLREIEGVSGVHIM
AHRQEAFVPEIIQRAGIPGARMPWTPEPRPTPFP
>A0A2N1HS40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciecola sp. 33A|TrEMBL
MVSYAQGIDALNQSLSELKDIDVSFEFFPPNSEAMENTLWKSVERLAPLKPKYMSVTYGA
NSGERDRTHSVVKRIYKETGVSTAPHLTCVDATPDELKLIAKDYWDCGIRRIVALRGDLP
PGIHKTDMYASDLVTLLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGANEAIT
QFFFDTSVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLQRFAGFTNVHVPNWLHKMYDGL
HADDQATRNLMGANIAMDMVKVLAKEGVKHFHFYTLNRCELSYAICHMLGLRSQK
>A0A1C5A7W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora mirobrigensis|TrEMBL
MALGLPSVLPNPQPAIGELIRAGRPTFSFEFFPPKTAQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVVGRLAGVGVRNVLAVR
GDPPGDPGGEWIAHPEGVRYAEDLVRLVRDAGDFSVGVAAFPYKHPRSADVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PTALAERFAEVADDPEAVHRLGVEQAGEMCRRLLDEGVPGIHFITLNRSTATREVWQHLQ
VGARV
>A0A838KDM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporichthyaceae bacterium|TrEMBL
MTETLSSARELSRALEAMQRQLLEAALRRPRYEVLPLDGTADAVVDHVPREVTVTVTASP
RRGMEPTLALSESLARQGYRVVPHLAARLVIDESHLRDMLCRISEAGIRDIFVIAGDGEP
AGVFPDSLRLLSALREGQGDGLGQHLEQVGVAGYPEGHPDVSDAQLTRALLAKQPSSTYL
VTQLCFSARTVSAWVDRMRAAGVSLPVYPGVAGVVDQRKLLRVAQRIGVGQSVRFLRKHH
GLLRLLSPGGYRPDGLVRELASRLAPSADDMAGLHVYTLGAVAATERWRREALEQTLEAV
DRHRSRRRRVAPPSRYSALALVRHGVTGQAWPRAWDRHEPRDGYDVVIVGGGVHGLATAY
YLATNHGIDNVAVLEKSYIGSGGSGRNTAILRSNYLTAEGVQFYDRSLQLYRRLAEELNF
NVMFSRRGHLTLAHSDASLRTMRWRAEVNKLSGVDSEVIDADEVQRLVPYLDTSTAARYP
ILGALYHPPGGIIRHDAVVWGYARAASAFGVHVHQDTEVTGIDVNDGRVRGVQTTRGPIA
APIVVNATAGWSSLISAMAGVRMPVQTFPLQAAVTEPVRPFLHTVVVSGTLHVYMSQTAR
GEIVFGASVDPFASYSTRGSLDFLEGLASHVLELMPSLATLRVLRQWAGLCDMTPDFAPI
MGRTHVEGFLVDVGWGTYGFKAGPVSGEAMAECIATGRTPELISAFGLHRFAEGELVGEK
GAAAVGH
>A0A8I1PDM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp|TrEMBL
MTTRPTDSRTAFADAIRRAGYEVLPFPSAHDKVLAHVPAEVPLTVTTTEAKGLEPTLDLA
VRLRAAGYRVAPHLAARLVRDKEHLTDIAARLGEAGVDRLFVIGGDAAEPVGVFPDALSL
LEALGDTGYSFESVGIGGYPEGHGRIPDAALSQALRDKAPYATHVVTQLCFDAATTTRWA
ARAGLPVHVGVPGAVSRQKLIRVSAGLGLGQSARFLAKQQSMFWRFFLPGGYRADRLLDR
LAPGFNGPLAGIHVFTFNDLEATEAWREQLLARLS
>A0A7Y3K6R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHIEDIFARDRTTFSFEFFPPKTDAAAEQLFEHIRHLEPLKPSFVSVTYGAGGSTRQRTH
ELVLRIRRTTTLEPIPHLTCISHRRAEIEEILSRYSHAGAGNILVLAGDPPKDAPHYDRS
NDDFQHAGDLVRFIQEFNRRGIHPDKRGFGIGAAAFPEGHPSTPNRLMEMDFLKAKVDAG
ANYLCTQLFFDNHDFYDFRDRCELAGIRVPILAGIMPISSLTGMQRMAELALGTHYPAPL
LRAIRRCGEDADAIRRVGTHWATEQCRDLLDHQVRGLHFYTLNHSGVTLEIFKNLGAVDS
QSLGAGGGL
>A0A2N5GPV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus canaveralius|TrEMBL
MSFLKKMENQILIADGAMGTLLYSYGTDCCFEELNLSEPEQILNIHKAYINAGADLIQTN
TYAANYLKLQRYGLEDSVKEINSAAVKVARNAAQDKAYVLGTIGGNRGIKPHSISIEEIK
RSFREQLYCLLLAGVDGLLLETYYDLKELETVLSIARRETALPIIAQVSLQETGILQDRT
PINEAFERLELAGADIIGLNCRLGPHHMLLTLEQVALPKHAYLSAYPNASLPAYVDGKFH
YEGDAEYFRKSAQPFREQGVRLLGGCCGTTPEHVRAFAEELKDKAPVTNKIVKLKEKKII
VETAIVKREEPPLDHVVKQRRSVIVELDPPRKLNTGKFFEGAKALQDAGIDAITLADNSL
ATPRIANEALGHLVKQKLGLRPLIHITCRDRNIIGLQSHLMGLYTLGLHDVLAVTGDPAR
VGDFPGASSVYDMSSFELIQMIKQLNEGLSISGKELGQKTAFSVGGAFNPHVRSLDKAVK
RLEKKIACGADYFISQPVFSEEKLIEIHDATEHIEAPIYIGIMPLISSKNAEYLHNEVPG
IKISESIRERMARFKDLPADASREGLEISKSLIDAALELFNGIYLITPFLRYELTVELSY
YARRHHNALTGRNDHVQTNIL
>A0A7J7ANV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Abscondita terminalis|TrEMBL
MNAVNASFTDYKVADISLADYGRKEIKLAEAEMPALMGLRKRYSAAKPLAGAKILGCIHM
TIQTAVLIETLVELGAEVRWTSCNIFSTQDHAAAAIAASGIPVFAWKGETEEEYMWCLEQ
QINVNGKPWDANMILDDGGDLTAVVHEKYPELIAKIHGITEETTTGVQRLHEMFRDGTLK
VPAINVNDSITKSKNDNKYGCRHSLNDAIKRGTDMLLSGRRALVIGYGDVGKGSAQSLRQ
EGMIVRVTEIDPICAMQACMDGYEVVSPYKNGVQTGKKEDINLDLLQNTDLIVTTTGNYH
VCDSAMLDTLKAGSVVCNIGHFDTEIDTNYLRGYKWKNENDYLILLSEGRLVNLGNATGH
PSRVMDGSFANQVLGQMHLFAEKFADLPEDQKAAKIRVELIPKKLDEEVAAAMVAGFGGV
LTQLTQEQADYLGVQVEGAEKLKIVHQELQQFNPEFFSITYGAGGSTRERTLAAINDFNG
KGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVRF
IREHTGDHFKIEVAAYPEMHPQAESYDADIQHFIEKVNAGANAAITQFFFNPDAYFYFVD
RIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHEV
VIKLCERLIAGGAPSLHFYTMNHTEPNRQLILDLGLA
>A0A8J6YYJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mangrovicoccus algicola|TrEMBL
MSAPRVSFEFFPPRSLEASFRLWDTVRALAPLRPTFVSVTYGAGGTTRKLTHEAVTTIGK
NYGLNVAAHLTCVDASRAETLEIAQSYAEAGVTELVALRGDPPKGADRFTAHPEGFADAC
ELIAALKETGQFTLRVGAYPDPHPEAKGDPLADVRWLARKFEAGADSAITQFFFEPDTFF
RFRDRCAAAGISAPVIPGILPIENWTGVRKFALRCGTPVPAWLDEAFDKAGPEGQDALSR
DLCIDLCRRLMAEGVEDLHFYTLNKPGLSRDICAALGVHPQGALEDVA
>A0A7J6YXE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Abscondita terminalis|TrEMBL
MMVQGQHARTRYLESVNAVMAAHQYGGFHIGVAFNPFKYTPAEQQAQYLKLHKKLNAGAD
YIITQLGFDLSALKQLQTFLAQEKYIQKTLACVMPLTLARAQFMVKHKVAGIVITPHMLE
VLTQDQVNQCPENAYKRSALQILICQHLGYAGVHLSACHKADEQMLLEQYIEQYRDLNLS
QCEILWNQLWQLAEGEQLRPKVAAKQIKSALNNKSSFVKGVGTFIFNASFWNRKTAAKVL
LQTEYLSKHYLLGCESCGQCRLAETLYICPETCPKGLANGPCGGTDLDRCEFGDRECIHS
VKSRLAHDVDQIQLLKEQLIPTVPIEVRGTSSWKNWYKQSS
>A0A433E1C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NP10|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVQYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PESLKERILAAKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A1H5EH30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces misionensis|TrEMBL
MNPAVTAPAAVGTALLDDFSLEMTGKDVPALQEARDSIPQGTRINVTFLAGEDHAARLAA
ARAVRRCGFVPVPHVSARRLPSRAALEEFLAGLAADGTADNVFVVGGDPARPEGPYEDAL
AVIRTGLLERYGVRHVGISGYPEGHPAITGPALWSALTDKAAAIGTGPFTGDVITQFGFD
AQPVLDWLAQVRARGVDLPVRIGVPGPAGVRRLLGYATRFGISTSASVARKYGFSLTNLM
GTTGPDRFLRDLSDGYDPARHGTVKVHFYTFGGLRTTAEWITDFQRRTR
>R0M7J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis 13/39|TrEMBL
RLLKTCENIHLPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNA
ETAKYIHQATHALFNHQSLG
>A0A5C6IVZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces misionensis|TrEMBL
MALGTASTRTDRARTVREILAGGKKTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDTDVAHFVD
KCRAGADYAITQMFFRPESYLRLRDRVADAGCDTPVIPEVLPVTSVKMLERLPKLSNADV
PDALKERILAAKDDPAAVRSIGIDFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A4P8GWZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. 24S4-2|TrEMBL
MMFPVRIEIIPSEGIVERVKASVPLTTTLTVTCLPHHGIERTMRTAVQLSILGYSVVPHL
AARSLHSRADLTGILRDCNVAGIGEVFVIGGDRKQPAGPYGSALPVLEDIAQYSGGAMRA
GVAGYPEGHPAIGPVDLLDALLAKQHLATHVVTQMCFSAPKILDYAALLRREGVGLPVWA
GVAGSVPRTKLVSLATQIGVGSSLKFLSRKGPLARKLLSGDRYSPQNLVSSLESQPGTIA
GIHLYSFNNLDAVPAEPDPASNPAAAVSTRGAAHVN
>A0A4P5XIH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHIADILKRDSVTASFEFFPPRNDAGWDSLFHVIADFERLQPSFVSVTYGAAGSTRTRTH
ELVARLKSKTKLDPIPHLTCTNHTRDDIENILIQYAQSGVSNILALRGDAPQAGSTASDF
AHAADLVRFIRQFNDRGIHPDPRGFGIGVAGFPEGHPDTPNTLLHMEHLRAKVDAGADYI
CSQLFFNNDSFFDWQERCQLGGIQIPVIAGIMPVTSIAGLKRMADLAGGTTFPAKLLRAV
QRCANDESSVERVGIHWATEQCMALLDKGVRGIHMYTLNKSDATRAIFQNLGLKSAADFR
>A0A0G3EGQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiritimatiella glycovorans|TrEMBL
MKDWFEPGRFLNEVLTPKQASENIEGDLEKFAEKYAITMDRDWVACITDNPLGMLSFEAM
ETLDAVEADVKPERVLVHLNTFHIKADLDRILAEMKEKGARYILAVSGDGSERMHRLEPG
ELGTGGTTVTSVELMEYIHREHPGDFVCGVAFNHYEPQDAERDKLRRKLEAGAQFIVTQP
VIRRHENVDWLRNAGVPVIVESFMSKRIDLVAECVGYDLPPEDRNYDPIANFVALRENYP
DFGVYLALLGMKKQIVRFDEALSTQRTVA
>A0A3D4CF36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKIKDIINNKKVTVSFEVFPPKQWDKIANTKKVVDEMVKDKPAFMSVTYGAAGTTSGFTT
EIANAIKQGGVEPLSHLTCLTSTKEKINSVLDELEANGIENVLALRGDIPKDFEMGENQY
YHNAFELVSEIKARNKFCIGAACYPETHPESKNRVEDIARLKEKVDCGVDFITTQMFFDN
EKFYNFREMCAIKEINIPIIAGIMPITNANQIKRSVELSNASLPVKFSKIMERFGENPDA
MKQAGIVYATEQIIDLMANGVNNIHIYTMNKPDVAHQIMEGLSAIINE
>A0A836LPS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 6112|TrEMBL
MEYLTSLHEIYPVRLEFAGYPAAITLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGKAR
DIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGFR
IGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKKAKSFLTKNNYSQQI
LACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDRVYLRCALQILICKHLG
FAGIHLSACHKPEEQMLLESYIEQYRHLELNVLEELWNSLWQVTTGKEFSPEIARFSRQP
TSKQLIKYRQLHVMHEAMFGSKIAKGFGRFIFKAFFWENALIAKLLLKTEVLSKHSLVGC
ESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKQTEV
LKEKLIPTVPLETRGTSSWKNWYLGAEA
>A0A6N2DEF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phormidium sp. GEM2.Bin31|TrEMBL
MSRLRSAIQAGEFLITAEVAPPKGGDPTHMLKMATCLKRRVHAVNITDGSRAVLRMSSLA
ASALLVQYGIEPVFQVACRDRNRIGLQADLMGAYALGIRNVLALTGDPVKAGDHEQAKSV
FDLESVRLLQTLNKMNRGLDFNDRPLSDGKLDLFAGAAVDPQLASWSGLQRRFERKIAAG
AEFFQSQLISDFDRLDKFMSQIAARYDKPILAGIFLLKSAKNAKFINKYVPGVHIGDDTI
DRLDEAADPLREGMAIAAEQIQQAQQLCQGVHLMAIRTEHLIPEILDMAGIPPISRPSSL
VR
>A0A8I0LX97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. CFBP 8764|TrEMBL
MTTITIPQLAEARRALEEPLFADLAGDVGISFEFFPPKSEKMDAQLWDAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLARLHPFEISVAAYPECHPESGGHDVDLDNL
KRKLDAGANRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFANACGA
EIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPSEKVAAA
>A0A357TQX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MQISQMFKRKPCVFSIECFPPKQTANFDKMKDNLRTMRTLNPDFISVTYGAGGSTGGVST
VEVAEFLKNDLNVEPLAHMICMGSDKAKAAQLLDQLNAAGVRNVLTLRGDRTPTRPESPD
FAHASDLAQFVWQTQPEFDIHAACYPEGHPEAATLAQDVANLRFKQEAGATHLLTQLFFD
NMHFYRFLNLARRAGITLPVSAGVMPIVKRSQIERTVALSSASLPSEFTRMISRYQDDPE
SLYAAGIDYAVQQLRDLIEGGADGVHLYAMNDAKVAAAVYEGIKDLL
>A0A5C3R3I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pterula gracilis|TrEMBL
MRITQKIEQAHKEDRVSWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFVNITWNAGGKSS
DLTAEIIRTCQSLIGLETCMHLTCTNMPKDKVDVALREAKKSGCRNILALRGDPPVGKEK
WEAIEGGFTHGVDLVKHIRAEYGDYFDISVAGFPQTITFPEKEAALEMQYLKAKCDAGVD
FIFTQMFYDADVFIKWVKAVRAAGITIPIIPGINPIQTYNGFLKSTKLSDTPIPQDLLDQ
LEPYKNDDEQVRLVGTKLVAEMCRKILDADIGIRRLHFYTLNLEKATKMLLEELNLVPRV
QTLKPLPWRQSLTPNRRTETIRPIFWANRTQSYLSRTENWDEYPNGRYGDSRSPAYGELD
KYGVVLKYSPEEALKLWGEPEDFEAIKKLFTNFCEGKVSALPWSDQGIASETSVISDKLS
KLNELGFLTINSQPAVDGVRSDDEVHGWGPSHGYIYQKAYLEFFVNPELLELLLNVIERD
NNITYYVINRHGDLRTNSHSDGPNAVTWGVFPGKEVVQPTIVEAVSFMAWKDEAFEIGQK
WADLYAEGSPARKAVTELIDNSFLVNIVQNDFKDPDAIFRPFFKAAEAYTNKN
>A0A0Q9NM20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Soil762|TrEMBL
MFPTRIEIIPSTGIVDQVQALVPLTTTLTMTCLPHHGIERTMRTSVELSTLGYTVIPHLA
ARSIHDRAELTRIMRECDAAGIGEVFVIGGDRKQPAGPYESALPLLEDIAQYTGGRMRAG
VAGYPEGHPTVSALDLLDALQDKQHLATHVVTQMCFDAPKILDFAALLRREGVNLPVWAG
VAGSVPRTKLVALATQIGVGSSLKFLSSKGTLARKLLSGDRYSPHTLVAGLESQPGIAGI
HLYSFNNLDAVPNEAAASSTTAHQPVLIRGAAREY
>A0A329W5G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus sp. S8-52|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSINRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGD
LPENSEKPKMYGVDLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFRQLKRFAVMTNVRIPSWMTRMFD
GLDDDPESANLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A2N9W2Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium zundukense|TrEMBL
MSFFRQSRRPDLGTNIRVSFEFFPPKTEVMEERLWETVTRLAPLHPEFVSVTYGAGGSTR
ERTARTIKRILTETDVNAAAHLTCVDATKEEVDTVVREFAAMGVKRFVALRGDPAGGVGA
HYKPTAGGYENGADLVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVEKVRRAGIYIPILPGILPIHNFTQVTNFCSRAGTHIPGWLTERFD
GLENDPQTHQLVASAVAAEQVLDLVERGVQDFHFYTMNRADLAFAICHLIGIRPGSAALE
ADLAGAAA
>A0A419FVS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MSFRDTLNSGKFTVTAEIGPPKGTDIKEMLHHMEILRGKIDAANITDNQSAVMRISSIAV
CKLAMENGLEPILQMTCRDRNRIGLQADLLGAYVLGIRNVLCMTGDHVSAGDHKQAKPVY
DVESVQLLKIVDGMNNGKDMSGNDLKGATDYFQGAVVTPESNPIEPQLMKFEKKVNAGAK
FFQTQAIYDIEKFKTFMAHARRFNVKIMAGIVVLKSAGMANFMNNFVPGIKVPQNLIDEL
KAAGKEKVLDTGLNIAARHIKQLKDEKICDGVHIMAIGMEDKVPTIMERAGLL
>R5T1B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:75|TrEMBL
MKITQLLQEDKVTLSLEVFPPKKDTAVEQVSQSVRAIAALHPDFMSVTYGAGGGTSAYTV
QLAQEIKAEYDVPSMAHLTCVSSTKETVKKQLECMQEAGIENVLALRGDIPADAEFPLPD
QFHYAVELVRYIKQIAPEMCIGGACYPEGHPEAVSKAQDIQHIKEKVDAGCEFLTTQMFF
DNSIFYNYMYRLREAGVLVPVIAGIMPITRKNQVGRSIQLSGSCVPARFKSIVDWFGDDP
AKMKQAGIAYATDQIIDLIANGISHIHVYTMNDPEVAAGIMNNLSAILH
>A0A5C3QSK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pterula gracilis|TrEMBL
MNLVQKIREHDPAKPFYTFEFFPPRTEQGFENLTTRISRLAQLNPLAISITWGAGGSTRD
RSLLLAGITQSDYGIDTILHLTCTNMVRGSIDDALREAKGRGIKNILALRGDPPRGEEYW
IATDPRFTHAIDLVQHIRSTPEFASHFCIGVAAYPDGHPDHGPEYDEDEEIECLKKKVDA
GADFVITQLFYDVDRFLEWVGKVRARGITVPILPGIMPIQTYASFIRLSKLTRTRVPDEL
TAALEPICHDDALVKDFGVTLAISMIKRLTTEGGLPGVHFCTLNLEKSVQRVLEEVGWTG
HHEVGHNAVILDSADLANVHASSSAPPPPPPLTNGVTKPSPLRNGSITPSPPDETHTTTE
SDSLILPAREAVSAASAGLTSFPNASSHEAGRGELNAAASWDDFPNGRFGDFKSPAWGDQ
GPWGNNALYITADQSTSWGSPHSIEALTTLFSSYLSSHLPSTPFSPLPLSPESQTILPHL
QRLTSFGLWTVGSQPSVDGAESTDSVVGWGPRNGYVFQKCFVEFFADGEVVEKLEGKVGR
EGGGWVQWFACNAEGDLRTNVPEEGRNAVTWGVFSGREIAQSTIIERESFLSWNEEAFST
WAQWASFFRPGTPERETLDGVRKERYLVSIVHHDYKRRDAMWEFLFSGESLV
>A0A356R353|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MHISEVLRTHHPAISFEFFPPKTERTFQELFEAISALMPLKPAYVSVTYGAGGSTRERTH
DLVVKLKRETDLTIVSHLTCVGSGRQEIHQILSKYQASGIHNIMALRGDPPKGCTAVEIP
EDGFQFASDLVWFIKQQFPEMGVGVAGFPEGHPGTPNRLQEMDNLKRKVDAGADYICTQL
FFDNRDFFDFCERCEVVGIKVPIIAGIMPIVSRKGMARMSELALGARIPAKLLRAMDRAE
NDVYAEGVGIHWATEQVVDLIDHKVKGIHFYTLNKSKATLKIYESLGIQSSESLQHPVE
>A0A354HNI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKLSNLYTKAKEEGKTVLSFEVFPPKKTSGIETVYKAIDELAKMNPAYISVTYGAGGTEA
NNTAIIAEKVKSLGVEPLAHLTCVNNDKVSVEKELDEFKSKGIENILALRGDIVPGVEPK
KDFLHASDLCSYIKARGDFELAGACYPEVHMEAKDMVEDIKNLKHKVECGAEHLISQLFF
DNEVFYKFQDMARCAGIDVPIAAGIMPVTNTKQIQRMVSMCGASLPANFSRIMQKYENNP
EALRDAGIAYAIQQIVDLIAHGVDGIHLYTMNNPYVAGKITEAIGSML
>A0A4S9H1B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVNVTWGAGG
STSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNVLALRGDPPRS
DEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQSHPEHQHA
TYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGLMPIQSYQ
ILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSGPKGFHFY
TLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSLANSAPQNRVV
VDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIPWSEEGLN
PETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVEFFCSHED
WTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIEAVSFRAW
AEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLLEA
>A0A7C3CEF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeodactylibacter sp|TrEMBL
MKVTEYFERANGETLISFEVLPPLKGGSMKAIFDTLDPLMEFKPPFIDVTYHREDFVYKQ
KASGYFEKTAIRKRPGTVGICAAIMHRYGVDAVPHLLCGGFTKEDTENVLIDLNFLNINN
VLALRGDARKFDGKFIPEPHGHKYAVDLVKQVSAINRGEYLDQNIENGLSTDFCIGVAGY
PEKHFESPNLATDLQFLKQKIDAGANYIVTQMFFDNEKYFEYVDACRALGIDVPIVPGLK
PLTKLYQLNSIPRLFYINMPEALSKEMMKAKDAAARKEVGTEWTIMQSKELKAKGVPCLH
YYTMGDVETIKRIAEAVF
>A0A077LLT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. StFLB209|TrEMBL
MMISLKQALNEQPFVCLVEFVPKPTAKSFESFETLMQRGDFCGWPLLGTIADRVGSRFDL
TPLDAYSRLSRPVPALVHFSGKDRERADLLGQLERIDNLGLEQLFIVTGDRLPGHEPGQQ
PVRYLESVSALMIARQARPHWLLGAALNPFKYREEESGAQYFKAEKKLKAGADFLSLQLG
FDAQKHLEALAWMRRQPSPKPMLACVMALTAGRARMLEHVAGTVVSPSMLEAVNAEAEVS
KAFAQQRSISRLGLQIVGLKLMGYAAVELSGVHDATQMHALEQAVNDWQAQITDLEQWSS
AWQASWQMPGLAPVSFQPAGETWQPGQSQARASNKEQLRYHLMDALHHQLFSRTTWLSRA
FGWAVRRPVCATAGGARLLHRLERSAKRPIVGCDSCGRCRLQDTLYVCPETCPKGLANGP
CGGTKLNRCEFGDRECIHSIKYRIAKTVQQTDVLSDRLIACIPVETRHRSSWPQWFEATT
PLVESTQELTTTSRLQEPL
>A0A1H0RBR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax sp. OV413|TrEMBL
MSLASHLPISLEFFPPKTPEGAAKLRTVREALYALKPEFCSVTFGAGGSTQEGTFATVAE
ILGEGVPAASHFSCVGATKATVRTQLATLQAMGVKRLVALRGDLPSGYGAGGEFHYASDL
VAFIRAETGDAFQLEVACYPEVHPQAKSADADLNAFAIKVHAGANSAMTQYFYNADAYFR
LVEDARKLGVTIPIVPGIMPISSSSQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFG
LDVVTDLCERLIAGGAPSLHFYTMNQSVATLEIGKRLGLPG
>A0A3S4IA13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella bongori|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVFSPR
MAANSGGARPHS
>A0A2L2K0T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia cyriacigeorgica|TrEMBL
MTFDNVRGRSTPGRPSSTPPIVSGTPSVVQSLRLHSSRAVPFSVEFNPPRDAAGEARLWR
AVRTFERMHPAFVSMTYGAGGSTKDRTVRVTGELAGETTLLPVAHLTAVGHSVAELRSLV
GAYADSGIRNILVLRGDPPGDPLGEWHKHPEGVEYAEELVRIVRDLGDFHVGVASFPQGH
HRSPDLDHDTRFLAAKLRAGAEYSITQMFFDVDHYLRLRDRLIAMDPVEGAKPIIPELMP
ITSLRTVKRAEELCGRPLPRAVIERLERAAGSGPEEDAAAVRAVGIEIATEMAQRLIDEG
APCLHFITLNFAKATGEVLTNLGYGVTAAPISA
>A0A730TR04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Rough O:-:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A235BNM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-3 bacterium JGI_Cruoil_03_44_89|TrEMBL
MPDFRERIREGVLIADGAMGTMLHSLGVPKGHCYDELNLSNPDIVKTIHRSYIEAGAELI
ETNTFGANRFILERYYDLGDKVMDINYRGAEIAREVVGESRFVAGAVGPLTRPYESMITL
SKVERLKIFKEQILPLIDGGVDIIIFETMADIEELKDAISALREIDMDFPSIAQLSFMGD
GKTLLGVDVVQAAKELVGVEVIGANCGSGPQGLYRAVKRMSYVTDAVLSVQPNAGYPGFV
NGKFVYPATPEYFAGYARKFVNIGVTILGGCCGTTPEHIRYMKEAVLGMQPRPRKLVTVK
IPRKTKREEVSISTPLKSKLTEKFVYTMEIDPPRGVKLDKEVAIAKLFKELGGDVINVAD
NPMAKLRMSPLPLAYYVKNEVGLDCILHFTCRDKNILALQSELLGAHALGIRNILALAGD
PPSVGDYPFAVAVFEITAKELVEMIHSLNNGYDRLGNPLSGHTNLFVGIASPIKDVDPQK
IWEKIDLGAGFIQTQPVFDIDLLRKFISFNFGIPVIAGLLPLHSMRQAEYLANEVPGMYI
PEEIIERMRRGVSGTDIARELLSEIKKLCQGVCIMPGRRYELVRELMQQ
>A0A0H3FLG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rahnella sp. (strain Y9602)|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRQIARDYWDSGIRHIVALRGD
LPAGGGKPEMYATDLVHLLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPHWMNSQFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPDIAVPV
RA
>F7V1U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. (strain SY8519)|TrEMBL
MNIRESIEQEVLVFDGAFGTYYTEKYPEEKLPCETANINHPERVLTIHREYLEAGCRALK
TNTFGAYPENLGKADQEAVIKEGYRLAQEAAAGKAYVFADLGPAPGNDAPERAEAFCQAA
EIFIRCGAQNFLMETNCSNEGIPEALQFIRERVPDAFILVSYAAFPDGYTREGFYFKKLM
TEISDTGLCDVVGLNCVCGSRHMGELLGRLGGTDMKLFAMPNAGYPTMRGNRTFYDGNAE
YFASQTADFVSSGVRIIGGCCGTTPKHMELVVGRLSGQRVPKLLRQPAHGTAKEPAVRAE
NPFFEKISQGKKVIAVELDSPKDTNLEKFMGCARDLKEAGADAMTIADCPIAQARMDSTL
LACKVKRELNLDVLPHMTCRDRNINAAKALLLAAHAEQIRNVLIITGDPIPTAQREEIPS
VFQFNSVKMAAYLQSLNEELFEDPFRVFGALNINAVNFDSELKRAKKKEEAGMVGFLTQP
VLSEEAKENLIRAHEELSGKILGGIIPVVSERNARFMESEVNGIHVSEEIIARYVGKDRE
EAENLACEISCRIAEEIAPYVDGYYLMTPFQRTKLMRRIISGISHLC
>A0A2E2U9A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovoraceae bacterium|TrEMBL
MKVIDHINSSKGETLFSFEILPPMKGQGISGLFNQVEPLMEFKPKFINVTYHREEYIYKK
REHGLLEKVSTRKRPGTVGICAALMNKFHVDTVPHIICGGFTKEETENALIDLDFLGIDN
VLALRGDAIKSEARFVPTPGGHEYASDLIEQIQTMNSGKYLNSEVENAFPTQFCIGVSGY
PEKHFEAPNFETDLKYLKKKVELGAEYIVTQMFFDNKKFFNFVEKCREAEINVPIIPGLK
PVSTMRQTTVLPSIFHIDLPVDLMNEIESAKDNQAVREIGVEWAIAQCKELKAAGVPCMH
FYSMGKSDNIQKIAREIF
>A0A387HQC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces hundungensis|TrEMBL
MLATGETTYSFEFYAPKTEKGERNLWNALRRVEAVAPDFVSVTYGAGGTTRTGTVEATQQ
ITEDTTLTPVAHLTAVGHSVAELRHTVGQYADAGIRNILAVRGDPKGDPMGEWVKHPQGV
TYAAELVSLIRESGDFCVGVAAFPEMHPRSTDWDSDIRNFVDKCRAGADYAITQMFFEPE
NYLRLRDRVAAAGCETPIIPEVMPVTSVKQLERLPQLSTAVFPEELRARMLAVKDDPAAV
RSIGIEFATEFCSRLLADGVPGLHFITLNNSTATLEIYENLGLHQQA
>A0A2N5EL13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chimaeribacter arupi|TrEMBL
MSFFHANQRDALNQSLAELHGQFNVSFEFFPPRTSEMEDTLWRSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRQIALDYWHSGIRHIVALRGD
LPPESGKPEMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQLQRFAALTNVRVPQWMTHMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGAVAPV
HA
>V7I5K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Youngiibacter fragilis 232.1|TrEMBL
MKIRDMLGKGNTTVSFEIFPPKTTYPMETIFETLEKLRDLSPDFISVTYGAGGSSQGHTV
EIASRVKKDFGIESIAHLTCVTSTKDSIRQMLQDIRNSGIENILALRGDIPDSFREDRSW
KPEYRYAYELIDEIVDFGGFSIGAACYPEGHVETRNKVDDLKYLKQKVDHGVDFLVTQLF
FDNELFYQFREKMDLVGIEKPVIAGILPVLNINQVKRIQEISGCNMPPKFLRILDRYEHD
PKSLQEAGIAYAVDQIVDLLSFGIEGVHIYTMNKPEPTRRIMESISTVRYSEARKVISR
>A0A0P7IVB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliiroseovarius crassostreae|TrEMBL
MTTPNISFEFFPPQSLEASWRLWDTVHDLAPMDPKFVSVTYGAGGTTRDLTHDAVGVIHK
QYGLNVAAHLTCVDATREDTLKIARDYAKVGVTEIVALRGDPPKGSQGFTAHQDGFASSV
ELVEALADAGGFHIRVGAYPEPHPEADGLQACVDWLKKKIDAGANSAITQFFFEADTFLR
FRDACEKAGITAPIIPGILPIENWNGVKKFATRCGTSVPAWLEDAFEKAKRDGREDLLST
ALCTELCSDLLDEGAQDLHFYTLNKPALTRDVCHALGVTPKVQLQNVA
>D0GJP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoleptotrichia goodfellowii F0264|TrEMBL
MKIKNLYENKNPVFSFEIFPPNKNFLEEKLKTVTKELASYKPDFISVTYGAGGTTKSGTV
EIASYIKNELKIETLAHLTCIGSKKQEIANFLKELKNNNIKNILALRGDIPQGENESIYN
RGDYKYASDLIKDIKENEDLSIGAAFYPETHYENNDLIDLFHLKEKVDLGADFLISQVFF
ENETFLRFREQAEKLSINVPLVAGIIPVTNATQIKRITALCNCKIPLKLEKILDKYGSNP
DSMKKAGIAYATEQIIELLSNDIRGIHLYTMNKTDTTKEILDNVSFVR
>A0A3P3QIS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararheinheimera mesophila|TrEMBL
MSFVSAQYLESINRNLQDVAGKVNVSFEFFPPKTEQMENTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASRSELERIAKDYWDNGIRHIVALRGD
LPPGNKEKPALYAADLVEILRSVADFDISVAAYPEVHPESPNAQFDLLNLKRKVDAGASR
AITQFFFEPEKYLRYRDRCAAVGIDVEIVPGILPVTNFQQLQKFAAMTNVAIPGWMNKAY
EGLDQDATTRNLVAANIAMEMVKVLSREGVNHFHFYTLNRSELTYAICHLLGVRPQAAVA
>R7NT58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:581|TrEMBL
MEVSELYKDKKKTLSFEIVPPEKNSELSSIDETLDILCELNPDFISVTFGTGGSENCNST
IEVARKIKEKYNIEPVVHLTCLNCSKAEIDLIAKQLQQSGVQNILALRGDKIPNVQAKND
FKYASDLIKYMKSKYDFCFLGACYP
>A0A5C5ZGK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobythopirellula maris|TrEMBL
MRISEAYGAGKFGVSFELFPPKTPEGERALYGHVERLMAYRPSYITCTYGAGGSTQDKTL
EIIARVRKEFGVSVATHLTCVGRTADQLRDYLARAESMGVENVVALRGDPPKGDDTFRAI
EGGYRYANELVTMIRQDFPGLGVAVAGYPEVHQEATDPKVDLENLKRKVDSGGEVVITQL
FYDNADYLRFRDLCQAAGLTAPIVPGLLPVTNLAQIKRITSLCGARLPEEMTAPLEAAGD
DADAQFAAGVEYAARQAQELIDAGAPGVHFYVLNKSQATSRVLDSVSLPATTMG
>A0A1Z5YVR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter cibinongensis|TrEMBL
MTNSLSNWLSEKRIDGLLSRNSKTPIPILSFEFVPPRTAPMEQRLWHCIQHLAPLAPHFV
SVTYGAGGTTQVGTLSTVLRLRRETDLVPAAHLTCAGATCEEVDDLARCYRDAGVHHIVA
LRGDPPAGATDYNPQPAGYACASDLVAGLRRIADFDISVAAYPETHPTASSPDADLDNLK
RKLDAGATRAITQYFFDSEIYLRFLDRCLAAGITAPIIPGIMPVSDYEQIVRFSAVCGVT
VPAWLRNLFDGTAENPDLRRIVASMVAVEQIRTLQTYGLNEFHVSTLNRADLTYAIAHSL
GVRPIQTNASHNVTDPLETTEIPDERETSTDFDTTKGLQEGAPPFMLRTLFG
>A3I2Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus machipongonensis|TrEMBL
MKITQHLENADKTLFSFEILPPLKGQSLKELLEGISPLMEFQPPFVDVTYHREEYIYKKH
PNGLLEKIRTKKRPGTVGICAAMMNRFQVDAVPHLLCGGFNKEETENALIDLNFIGVENV
LALRGDAPKTEGKFIPEPDGHHFASELVEQIVDMNHGKYLHEETETGFQTDFCVGVAGYP
EKHFEAPSMKFDLRKLKEKVDKGAEYVVTQMFFDNQKYFEFVDEVRAAGITVPIIPGIKP
ITTMGQITMLPRTFFLDLPDPLMDELEKCKTNAEVREVGIEWAIDQCRELIKAKVPSLHF
YTMSKAGTTYKIAKEVF
>A0A0J1MSP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. MGH109|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>E0IBJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus curdlanolyticus YK9|TrEMBL
MLKQSILNKKTGIITYGMTPPKNTHTPEKIEEISQKQIERLTGLDIDALILYDVQEEADR
IDEERPFPYLPTLDPEIYSQQYLSSLDIPKIIYRCVGKYSEAELTEWLAKDVERQRYTVF
VGASSSQQQVQLQLSDAYRLSKQHNDELTFGGVIIPERHMKKNDEHIRVVDKMLRGCDFF
VSQATYNVEASKNFLSDYYHHCQQNELDMVPILFNLAPCGSTKTLEFMKWLGISIPKWLE
NELKFSTDVLDKSIQLTQKIFEELLEFGLEKGIPVGCSIESVSTRKVEIEASIQMVKDIK
SMLDRKQLIEAIR
>A0A4R6LUN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enemella evansiae|TrEMBL
MPATENSKQTRISDKQTMIDPATAHTPGLLEGFSVEITGKDVPALIEAAPLLPRGTAVNI
TYLANEDAASRLRAAESVLSLGLHPVPHLSARRIRSAAELTETLAAYQQAGAADEVFLIG
GDPPSPEGPFPDALSLIETGVLEQHGVRSVGIAGYPEGHPKIADADLAEAMGLKLDAIAE
RGMAASIITQFGFDAEPVLNWIRGLRGRGIGAPVRVGVPGPAGIKRLLGYARRFGVASSA
GIAQKYGLSLTSLIGTAGPEKFLHALDDGLEPDIHGQVLLHFYTFGGVPATARWIDDHSE
EF
>A0A7G7ASK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium hwasookii|TrEMBL
MKIADIYKSKNLTTSFEVFPPNEKVGLEEVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHFTCIGSKKEEIDRVLEDLERNNIENILALRGDYPVDRELEPGD
FNYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVDAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A7S2DLA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyocha speculum|TrEMBL
LGADFGAEMSEGLLKGGAPGLHYYSLNLEVVVMGILERLGLKKKAADPKIIDLMKSHDPT
GQPWRALEFFPPRTASGVENLKKRLTRMKENSGCMYADITWGAGGTTSDATMDIAITLRN
YGHVPNMHLTCTNIIGSKVKEALQTAKENGIRNIVALRGDAPEGQEKWAATEGGFNCGED
LVKFIREEHGDYFGISVAGYPEGHPDKIHAVKDEATMSESEKGRSSLQTNADGTKTLSVC
SDADFSDELDYLKAKVDAGADFIITQMFFDVQVYLDFVTACRAKGIMVPVVPGIMCLNAY
GGFCKMTNMCKTRVPADLQKRMDAVQNDKDAVKALGAEFGAEMSEGLLKGGAPGLHYYSL
NLEVVVMGILERLGLKKKAADPKIIDLMKSHDPTGQPWRALEFFPPRTASGVENLKKRLT
RMKENSGCMYADITWGAGGTTSDATMDIAITLRNYGHVPNMHLTCTNIIGSKVKEALQTA
KENGI
>A0A6J4RNH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Solirubrobacteraceae bacterium|TrEMBL
MDLQRRIASRQGEFLLFALTPPRLSTSAERAQEIADVTFERLEPLGLDGLILYDIDDESD
RNPEERPFPFLPTMDPAHYLDRHLDAWHMPVVVYRATAKYTEQDLRNWISHQDTARRMAV
FVGASSRNRPVATTLRRAQQLRVEVKPDLLLGAVAIPERHTSKGDGHLRLTAKQQAGCSY
FVTQIVYDVNAAKNLVSDYAYECRDRGFDPVPIVFTLSVCGSVKTLEFLRWLGINVPRWI
ENDLRHANDTLDASLEHAEATALELMDFCRRMDVPFGVSVESVSIRREEIEASVRLADRL
RSELVR
>A0A6B3H3M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7982|TrEMBL
DFCVGVAAFPEMHPRSPDWDSEIRHFVDKCRAGADYAITQMFFDVETYLRFRDRLAALGC
ETPVIPEIMPVTTIRSLRRIPSLSTAAFPPPLAERMLAVEDDPKAVRALGIEHATEMCRR
LIAEDAPGIHFMTMNFSQVTTEIYRNLGLHAR
>A0A724LA32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enteritidis PT4 (strain P125109)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A352L298|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
ELSDWLHQAWQSGVRNIMSLRGDPPAGQQVFTAAEGGLNHASELTALIRRLYPEMGIGVA
GYPEKHVEAPSLDADLENLKIKVDAGADAVFTQLFFINRSFFEFRDQCAARGITVPIVPG
IMPITDFARIRRITSMCGSVIPLELATQLEAVRDDAAA
>A0A560B866|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum brasilense|TrEMBL
MTAPLSAPPSISFEFFPPKTESMEQGLWQSIRRLAPLAPSFVSVTHGAGGSTRERTHATV
CRIQDETGLPAAAHVTCVGATRDEIDTIAHSYWNAGIRHLVALRGDPSDMPGGSGRCEPS
PGGYAYAADLVAGMRRIADFEISVAAYPESHPEAPSVQFDLDNLKRKVDAGATRAITQFV
FDNDVYFRFLDRCAAAGIHVPVIPGILPITNVARAVEFAAKCGASMPARLVETFEGLDDD
PETRRLVAATVAAEQCQALQAQGVRDFHFHTLNRSDITLATCHMLGIRAAVPAP
>A0A4S0K5E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2E.F.Ca.ET.209.01.1.1|TrEMBL
MTVRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVLKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWQREIRRDDQIVAERLDHILHDELTETQVDMVK
TAH
>A0A524RV28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanocapsa feldmannii 277cI|TrEMBL
MLLRQALVEGRPALTAELTPPRGGETSAAMVAAAALRGRVHAVNVTDGSRAVMGMSSMAL
CRLLLDHGIEPVFQLTCRDRNRIALQAELLGAHALGIPNVLCLTGDPVKAGDQPAAKSVF
DFESVRLLRQVRALNAGLDPGGDGRRLPHGPIDLLPGCAADPQSGSWDGLKRRTQRKCEA
GARFAQTQMVTDREALRRFCGEIAGPLGLPVLAGVFLLKSARNAAFINRVVPGAKIPQHT
IDRLAAAPDPGAEGVRIAAEQVREFLGIAQGVHLMAIKAEALVPRILDLAGIAAIA
>A0A0A2BB03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus str. MIT 9401|TrEMBL
MKTKLQQTLEKKSKVITAELMPPRGGDPIRSLNIAQLLKDKVHAVNITDGSRAVMRMCSL
AMSKLLLENGIEPIMQISCRDRNKIALQSDILGANALGIQNILCITGDSVKAGDQQDAKA
VHQFESVRLLQQIQAFNKGIDPTFGELPDKKTFIYAGAAADPSCRNQRSLENRMRKKKEA
GAQFIQTQMVMEKENLIEFCEKIAKPLEIPVIAGVFLLKSHKNALFINKNVPGANIPENI
INRLKDAKNPLEEGIQIAAEQAQDYFHIANGIHLMAVKTEHLIPEILKKANLNLEY
>R7AGN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:379|TrEMBL
MELSTKKARPRLTFEIFIPEQAAPISKMMQTVDVLRSAKPDFVLATADHRHGTGLERAVE
FASMIQSEGGIPGAVLIPSICYTRTRLKLPLPQMKRRGITRILAVRGDGMRPDFEHADFP
SAAELIEFIKEVDPEFRVASGCFPENHPESLGIVTDVWQLRRQADAGACRMITRMFYSFR
YFEAVQNRLDIAGVYLPMDAGIMPILRKESVSLLRQDFGVRLPRSFAQRLAQYEDDPKGF
YEEGVKYANEQIRRLVAKSAPGVHIFSHNDPELITRLSHGFYDAVSDFQAGTLAQEFLSK
A
>A0A372FZ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora craniellae|TrEMBL
MALGLPSILPNSQPAIGELVRDCQPTFSFEFMPPKTEQGERQLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRHVIGRLAGAGVRNVLAVR
GDPPGDPNGEWVPHPDGVHYAEDLVRLVRRSGDFSVGVAAFPYRHPRSPDIDADTEHFVR
KCRAGADFAITQMFFDADEYLRLRDRVAAAGCDTPILAGVMSVTKIGTIERSEQLSGAPF
PPALAARFERVADDPDAVRRLGIEQTSEMCRRLLDEGVPGIHFITFNRSTATREIWQNLR
VGAAT
>A0A562QW24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium huanghuaihaiense|TrEMBL
MSGAMTDLTTPATADRQEGHLKRPAISFEFFPPKSEEMERNLWETINRLAPLDPKFVSVT
YGAGGSTRERTHSTISRILKETTLLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRG
DPAGGIGTPYSSHPDGYQSSADLVAGIKKRHADIEVSVSAYPEKHPEARDFDADLDTLKA
KVDAGATRAITQVFFDNDFYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRNGTTV
PDWLAAKFEGLDGDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLG
IRAKSAQKAA
>A0A3D2TIG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MTLAQAYGSKKFGLSFELFPPKTESGMTNLFCHVERFVAYKPSYITCTYGAGGSTQDKTL
EVITKVRERYQLPVATHLTCVGLTAEQLGAYLQRAQDQGVENVVALRGDPPQGETEFVAP
RGGFGYANELVEFIRQY
>K5D8V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula baltica SH28|TrEMBL
MICLMTLASVYQSTDCAISFELFPPKTSEGVELLCKNVERLMQFGPKYFTCTYGAGGSSQ
GTTLEVLQKVKQITKLPVASHLTCVGSTVKELEAYLTEAGRIGVDYIVALRGDPPKGTTQ
FEVTEGGLKYANELVELIRGRFGDLGIAVAGYPETHQEAVDFQTDLTNLKRKVDAGADIV
ITQLFYDNDDFYRFRDACEKVGIEVPIVPGILPVTNFKQAKRIASMCKAAIPQSLESAMT
EADDDQDQFRVGVEHARQQTIDLVNNGVPGIHYYVLNKSEAAAELLDGLSLTSC
>A0A2U9R8B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pichia kudriavzevii|TrEMBL
MNISSISVGKWAYPVCFFSFLFSGVISTKLKAMSVKITDKIASLGKDEPFFSLEFFPPKT
ESGMRNLYARLGRMSLLGPLFVTVTWGAGGTTAEKTTDLAVTCQEELGLTTCMHLTCTNT
PKSVIDDALKKAKASGIRNILALRGDPARDTSISHGIGEFKYAVDLVRYIREQYGDYFCI
GVAGYPEGHADGSFEELTQDPRKDMPFLVEKIKAGADFIITQLFFDVDKFADFEALVRSQ
PELRDTVIIPGLLPINGYNIFQRASKLSHASIPSKLLAKFPTEVQNDDDVVKDIGVDVLV
DIIDQIYKKTDNRVKGIHFYTLNLEKSIAQIVNKSDHLYKVVAKKESEIEADESSSDDDI
DDAITTAKRAAYANRFNTTNKVISDIKASTSLKMQHSNSSSSQLKKLISISAGHGVLGKD
ATWDDFPNGRFGDSRSPAYGEIDGYGPSLKVTSTKAYELWGYPKTKKDISKLFVNYLLKK
LNCLPWSELSLSPETALIQEELINLNELYYFTVASQPAVNCASSQDKIIGWGPSNGYIYQ
KAFVEMFVSKKDWNEKLLPKISKCGSSVSYYYADSKNYFDTNLPPNASNCVTWGVFPNRE
IVQTTIIEEESFKAWTEEAFEIWKEWKLLYKKDSDSAKLIDTILNEYYLVTIIHHEYPNE
SALWELLLDDE
>A0A3B0CN87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus ginsengarvi|TrEMBL
MKANLRDALKRQVLIGDGAMGTYLYQLGFPVGVSYEEYNLLKPDVIGDVHKQYYAAGARL
IETNTFSANREKLSKFGLEQDVAAINKAGVAIARGAVGEDAYVVGAVGAIRAARRRNIPQ
EQLESDFREQIEALLEGGVDGLLFETFYDLEEMRIAVRVARSLTDLPIIGQFATDGGTTT
NDGVDYQKAFDILVAEGVDVLGFNCHSGPNGILRTMEKLAPIPGTPYSVFPNAGLPGYVD
GKYVFGSKPDYFAENALKFARLGARLIGGCCGTTPEHIAAMAAALKDFDPAAVIADSVQK
PAGESAQASETSRPTVSSPAVPEQAKEPGLLELVAQRHTVIVEWDTPRDLDIGKFMQGAE
ALRAAGVDSITMADNALAVTRMSNLPLGILIKQQLGVRPLLHIACRDRNLIGTQSHLMGM
HAVGLDHTLVITGDPSRFGDLPGSSSVYDMTSFEMIRLIKQLNEGVAFSGKPLKHKANFI
VATAFNPNVKYLEKAVQRLEKKIEAGADFIMTQPVYDAKLIENVYESTKHLNVPIFIGFM
PIVSENNATFLHNEVPGIQLSEEVRRRMAGLSGEQGRAMGVQIAKELLDVAMPRFNGIYL
MTPMHFYDVSAQLTAYVWEKTGRQPLAR
>A0A7V2AJR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MNVTSKGRPPHPSLIVALPLPKDVRVSFEFFPPATEKAEQSLWACVERLAPVKPSFVSVT
YGAGGTTRQRTHETVVALAHKSDLSTAAHLTCVGSEKSEIHDIAERYWDAGIRHIVALRG
DAPEGDGSYRPHPDGYAYASDLVVGLKSIADFEISVAAYPEGHPEASSGQADLDNLKRKI
DAGASRAITQYFFDPEVYLRFLDRARATGIHVPIIPGILPVTNFKQVCKFSKLSGTAVPD
WLAAMFDGLDNDAETRKLVAASVAAEQCRVLHASGVKDFHFYTLNRADLSYAICHMLGVR
PATDCDGKSQ
>A0A7K9T452|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Galbula dea|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFDYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A3N5HFW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MNPTRRDTPFREAMRSLLVFDGAMGSLLYERGVFVTQNFEQLNVTRPEVVRKIHEDYVAA
GAQVIETNTFGANGFCLDRFGLGDQVRAYNVAGARLARQAAGEDVWVAGSIGPTGLVPGV
ASPAELDLAAATFADQAAALVEGGVDLFVLETFRHLEEIRIAIDAARQAAPELPIIASMA
FNPSETVADGSTPEQVAATLRDWGADVIGVNCGDGPQLALAIAERMRGAGLPLCVQPNAG
LPRTVDGRLLYMATPEYLDVFARRTIQLGATMIGGCCGTTPEHVHWMAKSGRMLGDRHID
VIRTRAVTAAEVVPVLEPTPLAERSDFAAKIAAGKFVVSVEVNPAPGLDPSKALEGAKML
LASGVDIVNVADAPRAVARMSNLAFCSLLLERCGIQPILHVCGRDRNLLGQMAHLLGAHA
IGIRNLVII
>A0A2V7GHN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MSAPFVARLVERPLLGDGAMGTMLYGRGVPLDACFDVLCINDSQLIQSIHAEYIAAGSDC
VETNTFGANRFKLGVHGLAGRVREINLRGAKLARDVRESMGRDVFVLGSMGPLGKYLAPL
GSVDPEEARAAFREQAEGLVEGGVDALIVETFSDLVEMRLAVEAIRSVTELPIVTQVAFT
DDGVTFLGRAPAEVVRTLRELPIQAVGANCSVGSSVLYDILEQMVPEAGGLPVVIQPNAG
LPSRVGERLIYLSSPAYMADYAARMITAGARMVGGCCGTTPEHVRAMRKALDRLVPGRGA
AQVASVRRARAEAVEPPSLSTTTAPTLLQRKLERQHFLVTVELDPPRGHNIEKLVQGAKL
LKERGVEIVDINDGSLGRVRMSVLPTAILVRDATGLDVNMHFTCRDRNLMGIQADVLGAH
AMDIRNILAMTGDPPRTGDYVNATAVFDVDAIGLIRILTEMNRGLDATGNPIGEPTAFCV
GAALNPAAAEPQQEMERFLAKAEAGARWAQTQPVYDLELIERFFARTRPPIPIVVGILPL
HSSRHAEFLHNEVPGITVPEPVRARMRDAGERGLRAGIEMAQSLLRDVRSRYMGAYLMPS
FGRFEVVAEVLDALH
>A0A8C5QIR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptobrachium leishanense|TrEMBL
MVNANGVDVASSSSSTENSKENSRCSTPILDLERYEPLRDKMRRRMEAGDKWFSLEFFPP
RTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGEPSSDKETSSMIIASTAVNFCGLETVLH
MTCCRQTKEEITKNLHKAKRLGIKTIMALRGDPIGEEWEEEKDCFNHAVDLVKHIRQEFD
DYFDICVAGYPKGHPEAESYKQDLKHLKEKVDAGACFIITQLFFRSETYLKFLKDCRDIG
ITCPIVPGIFPIQGYCSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSMCR
ELLDSGLVHGLHFYTLNQEVATISVLKRIGMWAEDPRRPLPWAVSAHPKRRVEDVRPIFW
ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGDLKDYYLFYLKSKCSRELLLKMWREELSN
EESVYEVFTSYISGEPNRKGHKVTCLPWNDDPLAPETNLLKEELQKVNKRGILTINSQPN
VNGKPSTDPIFGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYQIVNVQGEN
ITNSTDLLPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEEESPSRM
IIQYIHNNYYLVNLVDNDFPLENCLWQVIEDTFKEHDNPTE
>A0A4R8A6M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Breznakia blatticola|TrEMBL
MHIDQILKKKKTLSFEIFPPKNKSGDISSIYQTVEALKDLDPDFISVTYGSGGSTIGKTL
EIADVIKNTYGIEPMAHLTSIVSTKEDVNDFCMKLKESNVDNILALRGDMPLDDRVVCPK
QFSYATDLIKHIQETFPNDFCLAGACYPEVHQEADCFENDLKALKAKVDAGAKFVITQIF
YDNNYYYRLVREARKIGIDVPILAGIMPALNAKQLLRTTRMCGCTVPFELSTRIEKYYYN
DDAMQEVGISFAVNQIIDLIANGVDGLHIYTMNRPEIAKSIFAQIPNILKDFYHYD
>D0Z2L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium damselae subsp. damselae CIP 102761|TrEMBL
MQPITNYQALSLQDSELRVRYNDVTRGVYFIGTTPPKTSTDLSDVDGIADKLVDRIKDLA
FDGLIVYDIQDEGSRISKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSEPEVFN
QWLNEAWEQYQVRDIVLVGSPSTQNQVSLPLHEAYKTIADNEHPFFTGGIMIAERHAKKG
NEHQRLIEKYQQGCNFFISQAIYDTQATIDLLTRYAIECQEKGLKPQRIILTFSPCGSAK
TLEFIEWLGVSVPEATSLRILNADNPLHESIKMCCNSLNQILEAVVEYDLPLGLNIESLT
NRKEEIEGSILLYKLLRSTMDMYLAQHEFRKQQGLKKAF
>M3G4U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira weilii serovar Topaz str. LT2116|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPDGDLKLMETVKELARLDPDFVTVTYGAGGSTRDK
TVQILSEVSKRYSFPAVSHFTCVGANQDQISKTLKEIRSSGIVNLMALRGDPPKGEGKFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPDAKSLEEDVENLKQKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A1B6ALR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NBRC 110611|TrEMBL
MRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTAELRNIIGQYADAGIRNMLALRGDPPGDPMGEWVKHP
DGLGYAADLVELIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVNKCRAGADFAITQMFF
YPEDYFRLRDRVRAAGCPTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYKNLGLHQRS
>A0A1G3V3A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium RBG_19FT_COMBO_59_10|TrEMBL
MKAGSNLEKVFAQGHFAVTSELGPPKGNDVGVVQRKVDFLRGYVDAVNVTDNQTAIVRMS
SIAACAFVIRMGMEPVMQMVTRDRNRIAMQSDLFGASALGIKNIVCLTGDHHTFGNQVNA
KNVHDLDSVQLINMVKTMRDEKMLLGGEEKIEGDINMFIGGAANPFGDPFEFRALRTAKK
AAAGVDFIQTQCIYDMERFKEWMKMIRDLGVHEKVHIMAGITPLKSAGMARYMAKNVSGI
TIPQAIIDRMAKAAKGAEEGIRICVEQIEQVREIEGIHGVHIMAIEWEQMIGRIVEQAGL
LPRPKVE
>A0A0K8J2N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbinix luporum|TrEMBL
MKICELFQMKKVFSFEVFPPRRIDSVNIIYDTIEKLKGLNPDFISVTYSAGGSESNADTF
KIASAIKNNYGIESVAHLPSINHTKVEVLKILEDLRTAGIENILALRGDVNPSFSPKNDF
KFASDLISFIKEHGDFNIIAACYPEGHFESPSIIDDIRNLKRKVDAGANQLITQLFFDNN
CFYSFRERAAIAGINIPIEAGIMPVVNKKQIERIVALCRVNLPKKFLAIMNRYENNPEAL
RDAGIAYAVDQIIDLIAQGVDGIHLYTMNNPYIAHRIYEAINTLLVA
>A0A2M8WJ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimicrobium subarcticum|TrEMBL
MSVGPAIARAGSGTAPRPTVSFELMPPRNPAAAPKFWDTATRLVAARPDFVSVTYGAAGN
DRDTARHVVARLIRETPVVPVAHLTCVGAARGDVAEVIDDFLADGVRSFLALRGDPPVDK
PDWAPAPDGLRSSDDLVHLLREVEARRCASHPGDALRGAHRPLTIAVAAFPAGNLAAGTT
RAQEVQRLLEKEQAGADFAITQICYEPETYTGFVDEARAAGVTIPILAGILPMTEPRRLH
RVEELTGVPVPQHVLPALEAADDDAARHAIGVRHTVDLAQAVLDAGAPGLHVYTFNKHHA
ALDLLEGVHLGGRGTDDTSDLLDLASGPWVRDHHPHDVPGSHDMASAKGTGDG
>A0A0Q0V451|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. PA-3|TrEMBL
MGLLDELKQRVLIADGAMGTLLYSHGIDRCFEELNLSKPEEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPSINRAAVRLAKQAANGRTHVLGTIGGLRTLNKSAVPLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLTIARKETTLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLQSLEEVPLPTRAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIEAMARALQDRKPVTKKTVKRRAVSVS
VQADNPSAVTPLPELARTRRSVIVELDPPKQLGIDKFLVGAKALHDAGIDALTLADNSLA
TPRISNVAVGSIVKEQLGVRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLISQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVER
MEKKIQYGAHYFLTQPVYSEEKIVEVYEATKHLHTPIYIGIMPLVSARNADFLHHEVPGI
TLSDEIRARMAACGNDPVEATREGIAIAKALIDAAFDLFNGIYLITPFLRYDMTVELIRY
IHEKEAAAKERKVVHG
>C3E8J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar pakistani str. T13001|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8B4BV19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weizmannia coagulans DSM 1 = ATCC 7050|TrEMBL
MPPFPGGFFHIMQRECKKLDFLETLKNRILVADGAMGTLLYAYGANTCYESFNLSHPEDI
HAIHRAYIEAGASVIQTNTYSANYIKLAQYGLEEKVKDINKAAVRIAKEAANRDTFILGT
VGGIRGQRKTEATLAEIKRTFREQIFHLLNEGVDALLLETYFDAEELYTVVDIAKKEADV
PVIAQFSLIEPGVLQNGTPVRDAFKELENRGADVTGLNCRLGPHHMIQAFEEIPIPKRAF
LSAYPNASLLDYEEGRFTFTNNADYFKTCAEKLVEQGVRLIGGCCGTTPAHIKAIAEGVQ
GLLPVTEKTVRPPKIEIAAAPAQYEPPLHEIVKKSRSVIVELDTPKTLNTARFFEGAKAL
HDAGIDALTMADNSLASPRISNTAIAAILKEKQGIRPLVHITCRDRNLIGLQSHLMGLAA
LGIDQVLAVTGDPSKIGDFPGATSVYDLSSMELIAMIKQFNDGISHSGKSLQRKTNFSVA
AAFNPNVRNLDKTVGRLERKIRHGADYFITQPVFSTEKIEQIHEATKHLDAPIYLGIMPL
TSYRNAVFLHNEVPGITLTDDILQAMEKTNGDPVKAREESLAISRTLIDAALAYFNGIYL
ITPLERYELTVECTRYIHEKTAVRSAGIF
>A0A5E6MM47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylacidimicrobium cyclopophantes|TrEMBL
MANLLELLSQRLVLGDGALGTYLYTLGLPRRYCLEEANLSRPELVQRAHADYRQAGAELL
RTNTTGANRASLSRFGLEGRVVEINRRGVELARAAAGGGESLIAGSVGPIWLRPWDGSLS
PEERRTLYQEQISALLDAGCDLVFLETFTELPEAMLALRVAREAGSPIVAVSLAVFEEGR
LGNGETLASGLAALWGAGAGLVGIGGSCGILASLHLLEGIEVRAGEFLCAFPNAGKPEFY
EGRLTYSASPKYFAASVDRFVEEGVHLLGGDYGTSPLHIAAMAPILARHRPRFVKAARAR
LSVVEAVREEAPPGTREESLLDRCKRKPVAIVELDSPRTLAMDKFLEGVRALEKAGADAL
TLADNSLAILRVSNLAAAVAAQRCSRLHTVLHLACRDRNLLGLQSELLGMSVLGFRHVLA
LTGDPAKAGDHPGATSVYDLNSLGLIKLLAKLNSGVSAAGRDLKAKTDFVIGCAFNPNSV
QFDSQVRKLESKIAAGAQFTMTQPVFDAERIRKSAERLKPLGIPVFVGVMPVLNSRNAEF
LHNEVPGISIPEGVRERLRHLEGPKAAEVGLELARSLAETVLECFGAVYLITPFLRYDLS
VRLLEELF
>A0A7R6WKQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 113-1-2|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILNETSLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A3C0NWA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilaceae bacterium|TrEMBL
MNKNISYSFEFFPPKTAEGITNLRQTRVALAKLNPEFFSVTFGAGGSTRDRTMDTVFEIQ
AEGYVAAPHISCISSSKEEIKALLSAYQAKGIKRLVTLRGDVPSGEVSVGDFKYANELVS
FIRQETGDWFHLEVAAYPEFHPEASSASQDLINFKRKIEAGADSAITQYFYNTDAYFRFV
DACLAQGIQVPIVPGVMPIYNFTQLARFSSVCGAEIPRWLRLRLEAYGDDMTSLRAFGVD
VVTDLCQKLIDSGVKNMHFYTLNQAGTISKIVSNLA
>E6UHW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7)|TrEMBL
MKTCEIFKNKTSLSFEVFPPRSDTPIDSIYSTVDELAHLKPDFISVTYGAGGNGSNATIG
ICEMIKEKHSIEPVAHLACINLTREKVLFELAQMKAAGIENILALRGDVNPNIPPHDDFK
YASELIELIKENGDFNVIGACYPETHPEAASGVEDIKHLKEKVDAGCSQLISQLFFDNED
FYAFREKAAIAGIDVPIEAGIMPVTNPKTIARMATLCHARLPKKFLTIMQKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIASKICEAVQTLFR
>A0A519GXP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp|TrEMBL
MGLPLSFEFFPTKTPEGAIKLRAVRQQLYARKPEFCSVTYGAGGSTHDGTFGAVREILEE
GCDAASHFSCIGATKATVRAQLAELKAMGVKRLVALRGDLPSGYGIGGEFHYASDLVSFI
RQETGRDFHIEVACYPEVHPQARSPEADLQAYAAKVRAGADSAITQYFFSAEAYFRFVDE
SRKLGLDIPVVPGVMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDIASIKAFGLDVV
TDLCVRLRDGGAPALHFYTMNQSQATLGVLERLG
>A0A6A7MSB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriales bacterium|TrEMBL
MALGHRSPDSDGAATIRQHIAGGHKSFSFEFFPPKDDDGERRLWKAIRELESLQPTFVSV
TYGAGGSTRDRTVRITEGIASDTTLTPVGHLTCVGHTRAELRTIVGRFADAGVGNILALR
GDPPDGPGSPWVSTPGGVEYASELVRLVKELGDFNVGVAAFPEGHREAKSVDDDAFVMAE
KFKAGAEFAITELFFRPADYAALVERSDRAGADLPIIPGIMPITNLRQIKRFAELSGRDV
PAEVVSRFDGVTEPVDVRKIGVEIATEMCIALLDQGAPGLHFYTLNRSTATREIWANLPR
>Q30YC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20)|TrEMBL
MHPAGVTWQHTTATAHLRSNKDSDVKIKDLIGQHDGPFYSLEYFPPKNPEMWPKFFANVG
RLMALNPVFCSVTYGAGGGTQDNTFEITRRFKQDLDLEPMPHLTCVGATKDKIRGFVSQL
RDIGVDNVLALRGDAPADAGFSWDDGEFRHASDLVEFVNAEFPEMCVGVAGYPTAHPESA
SFAEDLHWTKAKIDAGSDFIVCQLLFDVREYFHFVAQLRAMGVTSPVLPGILPIQSLESV
RRILSLCGANIPGRFYLQLEEADAKGGAAAVKELGTKFAADMIRRLVDGGVPGVHLYTLN
QAETCLRIAEMAGPLR
>A0A1Q7BUZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium 13_2_20CM_2_64_7|TrEMBL
MTPRQPASRLETLLRAGQFAVTAEITPPVSCVAEDLLRKARPLAGLADAVNITDGAGARA
HLSAPIAACLLARAGIEPILQFTCRDRNRLALQADLMGAAACGVHNILCLTGDDPKAGDQ
PQTKAVFDVDSVTLTAMARELRDKGELPSGRKVLGRASFFLGAADVPIDPPPSWRPDKLA
AKLAAGAEFVQTQFCMDAGIVRRYAARLLEHAPTRGVFLLIGVAPLRSARSARWMQQRLY
GTIIPERCIERLERASDAAAEGERIAVELIEELAAIPGVAGVHLMAPANEDALPRVITEA
RKRQPSR
>A0A1X6X2Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium nesterenkovii|TrEMBL
MTERHDDLDLAGSMLLRAPSLEMTGKDVAALREAAPLIAPGTRINVTFLGNEDRPMRVGA
AKAVADAGFTPVPHVAARRMASTAEFAEFLDALRSEVGSTLLFAVAGDPAEPMGPYASSL
DLIRSGLPAEHGFTEVSIAGYPSGHRHLSEAQLWEFLEAKVAALREQGLTGSILTQFGFD
SVPVLDWIREVRARGIDLPIRIGVPGPAGVKRLLTYASRFGVASSASIARTYGFSLTNLL
GTAGPERMIRDLDAGLGADTGDVALHFYTFGGVLATARWIAQHRPAEPA
>E6UE60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7)|TrEMBL
MKTADIFKNKTVFSLEIFPPRPDTDESVIYDTLDHLTDISPDFISVTYGAGGGKNGSRTI
KIASDIQNRYGVESVAHLPCIGLTKEQARVILDSMSDNGIENILALRGDLPEGSTPAGDF
RHASDLISFIKENYSFNILAACYPEIHPESRNAVDDLHWLKHKVDCGADHLITQLFLDNS
YFCDFREKALLAGVDVPIEAGIMPVTNKRQIERMVKLCGVDLPKRFIRVLEKYEHDPNAL
RDAGIAYAIDQITDLIALGVDGIHLYTMNDPYVAHRIFDAVHNMLAVRSLVS
>J3TW19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Carsonella ruddii HC isolate Thao2000|TrEMBL
MKHISFEIFPNKNIKESILFINYLIKKSPKFITITCGKIDNYNFIKNIKKSINIKIIPHI
ICNDFFLLVKKIINFIKIKIFDFVIITGDNSKLNSFNLIKKIRILFGHIIRIYSGLYLEE
HKLTKNILNEILFIYKKKKIGINVFISQFFYNYNLIIYCVNILKKIGINKNFIIGIFPKK
NIKEIIYFTNKCKIELPIWIIKNFNYINFKNYYFKNLKKSKMFHFYTFNKKEYVEYYLK
>A0A7T0BYV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitronauta litoralis|TrEMBL
MKISELLKKVNPAFSFEFFPPKDEAGFDQLFNTINELKPHNPAYVSVTYGAGGSTRAKTL
DLVARIKCEIGLESMAHLTCVGSTRDEIHDILGSLKKSGVRNVLALRGDPPKGETEFVKP
QDGFGFANELVEFANQNFDFSIGVAGYPEKHIECSDLTTDLDNLKRKIDAGGEFIVTQLF
FDNRFFFEFMDSLQSRGIHVPVIAGIMPIQSYKQILRFTKMCGATIPGPLLSRLEKEKDN
PDAIKAIGVSHALEQCEELLANGTPGIHFYTLNRSNATRQILEGLNHTTFPSPE
>A0A8E3VW31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia vermicola|TrEMBL
MSFFHANQREALNQSLAELDGQINVSFEFFPPRTEEMEQTLWKSIDRLKNLKPKFVSVTY
GANSGERDRTHSIIKDIKDKTGLIAAPHLTCIDASREELKEIARDYWNNGIRQIVALRGD
LPDNSRKPDMYAADLVELLKTEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPSWMNKMFE
GLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A7G8GXN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. RS9902|TrEMBL
MSTALQRAIEAGDQVLTAEVMPPRGADSSHMLAMAASLQGRVHAVNVTDGSRAVMRMSSL
ASCKLLLEAGLEPVLQMACRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAGDQADARP
VNEFESVKLLQQVDALNRGVDPVQGALPDGATALFAGCAADPQSRSWSGLQRRLQRKQAA
GARFVQTQMVMDPEALERFQHELAGPLGLPVLAGVFLLKSAKNAQFINRVVPGACIPDAL
IHRLECAENPTMEGVAIAAEQVQRYLGIVRGVHLMAIKAEERIPLILDRAGLSSLPG
>A0A014CWB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_4|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGVRIGGAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKAFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELNVLEELWNSLWQVT
TGKEFSPEIVRFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKDKLIPTVSIETRGTSSWKNWYLGAEA
>A0A0B2U8S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter oleivorans|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDTIDKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHAYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGNTDR
IYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELEALEELWNSLWQVT
TGKEFAPEIARFSHLPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENTLVAK
VLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEVLKEKLIPTVPVETRGTSSWKNWYLVTL
>A0A6G6PPV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia sp. 1701011|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSEEMEQTLWKSIDRLKNLKPQFVSVTY
GANSGERDRTHSIIKDIKDKTGLIAAPHLTCIDASPDELKAIARDYWNNGIRHIVALRGD
LPDNSRKPDMYAVDLVELLKGEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPAWMSKMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A1S6RH01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces hygroscopicus|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRAELRNIIGQYADAGIRNMLALR
GDPPGDPTGEWIRHPDGLDYAVELVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPLTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATEVCARLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>R2TXH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus moraviensis ATCC BAA-383|TrEMBL
MRTDSLFKEKTVFSYEIFPPRRTAPIDTIYHTLERLKGQQPDFISVTLGAGGAGANLSTA
DIAQKIQEEQFLPSVAHLPAVNFSKEEIVAILEELKQKKVENILALRGDILPDKTPKKDF
IYANDLVAFIKEQGDFNIIGACYPETHSDAENSVEDIRNLKRKVDYGTNQLITQLFFDNN
YFYTFKEKCDIAGIDVPIQAGIMPVVNKKQIERMVKMSNVDLPIKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVAQGADGIHLYTMNNPYVAQKIREATRSLFNA
>A0A126NQ09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. KCTC 12332|TrEMBL
MTAISFEFYPPKTDDQRAQLDRTAVKLKPHAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLHAAPHLSCVGGTREEIRELLKLYRAIGVKRIVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLQHFKTKIDAGADAAITQYFYNADAYFHFVDA
VRKLGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWVSKRMQAYGDDAEAVREFGADVV
AGLCERLIVGGAPALHFYTLNLAKPTNAVLERLGRS
>A0A2V5ICK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus indologenus CBS 114.80|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKHHGDYFCIGVAAYPEGHPADNFQDGQDPARDVPYL
VEKTQAGADFIMTQLTYDIDAYTKFENMLRNHESGAFKTIPIIPGLMPLHSYKILTRVTK
LSHVKIPPHILSKLEEIKHDDDAVKRAGVDIVCDLVDGIRSIPTPGLRGFHFYTLNLEKT
VSFLLERCDLIGPYTEYDEPIEDSAAYSAARLETPALALASRRSSVSSMPHNRVIVDKLQ
PSDVSSRESVSHEATALSAGLPALPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHILPAVAHKVWGYPVTRDDISALFRRHVSGELYIVPWSEGGAEEGSG
TLNAETEIIRPELLQLIDKRGWWTLASQPAINGVRSDDPIFGWGPPGEGFVFQKPFVEFF
CPSADYQTVLKPLFERHGHEKLAWFATNARGDFESSLPGSNAEDPDPIDINPANVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDATKNDVWLVCVV
GQEFGAGTEVGSKEEEAETKWMWRELAGC
>A0A084IR57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinisphaera hydrothermalis (strain C41B8)|TrEMBL
MSHDVSHNDFSIELFPPKGPKGDARLTEALESLAELHPAFFSVTFGAGGTTRSGTLDTVR
KAMKITGRPAAPHLSCIEGTRESIGELLDSYKAAGVKRIVALRGDLPDGMDKPGVFNYAN
ELVAFIKERHGNDFHLEVGAYPEYHPAAASPAEDVDNFVRKVKAGADSAITQYFYNADAY
FNFCDEVAARGVDIPIVPGIMPITDFGQISRFSAMCGADIPRWVRQKMESYGDDTASVQA
FSRDLIGRLCERLLAGGAPGLHFYALNKAEPTATLWHDLKLPGPARHSAA
>A0A2G3K0J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinimonas sp. BJB300|TrEMBL
MSLSPTFSFEFFPPKTAEGIEKLRNTRRQLAQFKPAFFSVTFGAGGTTQEGTLATVLEIK
SEGFEAAPHLSCVGSTRENVAGLLRTYRDHGIRRIVALRGDIPSGMVEFGEFRYANELVE
FIRTEHGDWFHIEVAAYPEYHPQARSAHDDIANFIRKARAGANSAMTQYFFNPDAYFAFV
DEVSARGVDIPIVPGIMPINNFSQLARFSDACGAEIPRWLRLKLQSYGDDTASIKALGLD
VITDLCRKLLDGGAPGLHFYTLNAAGNVSTIWQRLGLADIRNYSPGN
>A0A0U1KJB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia mollaretii|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLRDIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>D4BEK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter youngae ATCC 29220|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>R0ANA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster bolteae 90B8|TrEMBL
MKIRDILAEGKPTLSFEVFPPKTEDAYDSVEKAAAEIAKLKPSFMSVTYGAGGGTSEYTV
GIASAIKEEYGVTPLAHLTCVSSTREKVHHVLGELRERGIENVLALRGDIPQDGSTPKEY
HYASELIREIKKAGDFCIGAACYPEGHVESANKSVDIDYLKQKVEAGCDFVTTQMFFDNS
ILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTYLPSRFMSIVDRFGDNPAAM
KQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A2T8F5R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides gansuensis|TrEMBL
MAVDYGPDVDLQRRIIEGQGEFLLFALTPPRQTASPEKAQEIADITAKRLQPLGVDGLIL
YDIDDESDRNPEERPFPFLPTMDPADYLSRYLNDWNTPVVVYRAVGKYAESELESWLRAQ
EPERRLSVFVGAASRDKPVATSLGRAQILRTQARPDLLLGGVAIPERHTRNGNEHLRLLR
KQAAGCSFFVTQVVYDVKAAKNLVSDYRYECLAQGLTPVPIVFTFSVCGSTKTLEFLRWL
GVDVPRWIENELLHADDTLEASFEYALAAARELITYCRRVGAPFGLNIESVSIRRAEIEA
SVDLAAQLRDELHRSD
>A0A413T5U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium ventriosum|TrEMBL
MNIADLFKKEHTVFSFEVFPPKKESGIETIYSTLNELKNLNPDFISVTYGAGGKGVANAT
TIDLCSYIKNELGTETIAHLSCLYNTKESIDRILDELDEKGVKNILALRGDVNPDFAIEK
DFKYASDLTAYIMSKNRGFNISGACYPEVHQEAANMIEDIQNLKKKVDSGADHLISQLFF
DNQVFFDFQEKARIAGINVPIEAGIMPVTNKKQIERMVSMCGASIPAKLSKVLQRFGDNH
EAMRDAGISYAIDQIIELAAHGVDGVHIYTMNDPYVARRIFEGVKNILKSGK
>A0A1E7HSL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium C00003094|TrEMBL
MHILDIFSANPTTFSFEFFPPKTDKAANRLYETIRQLEPLKPHFTSVTYGAGGTTRERTH
ELVMRIQEQTALDPIPHLTCVGSSAAEIEQILTTYAEAGVSNILALAGDPPPEQPNYDRS
QDAFPQAADLVRYIRQFNERGLHPDKRGFGIGVAGFPEGHPSTPNRLLEMDYLKAKVDEG
ADYICTQLFFDNRDFYDFRERCLLAGITVPIIAGVMPIASIEGMKRMADLAGGTRFPAAL
LRSIQRCQDDAEAVRNIGIHWATEQCRDLLDNQVRGIHFYTLNNSDATKLIFLRLGLKTQ
>F5T3R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oribacterium sp. oral taxon 108 str. F0425|TrEMBL
MSIVDLFSRKTVFSFEVFPPRRNAPIETIYETLYELQDLRPDFISVTYGAGGGENKQSTI
SIAEHIKNICHVPSVVHFPCIGLTKEDILDKIEEFKSAGIQNILALRGDIPEGMENRGDF
RYASDLVAFLKENGDFRISAACYPEGHIENPDKVADIRNLKTKVDAGAEYLISQLFFDNE
YFYDFLEKCDLAGISVPIEAGIMPVINRRQVLRMAGLCGVKIPKKFQRILEKYEDNSVAM
RDAGIAYAVDQIVDLLTHGVDGVHLYTMNNSYIAREIYKATHSLFDTGEKGEKEGTSASA
>A0A1V3PHJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. C01|TrEMBL
MPAISFEFFPPKTDEQRTQLDRAAQALKSYQPEYASVTFGAGGSTLSYTGDTVARLHQQH
GLNVAPHLSCMGGTRAEITELLDGYRTAGYRRIVALRGDLPSGMATAGDFRYASELVAFI
REHSGEHFHIEVAAYPETHPQADDALRDLQHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VRRLGVNVPIVPGIMPIANYSQLKRFSDMCGAEIPRWIAKRMQAHGDDAESVRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRARATQSVLQQLS
>E9RU88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 6_1_37FAA|TrEMBL
MKIIDKLQENKIHISFEIFPPKTDAGIEAVLSATEQIAKLAPAFISVTYGAGGGTSKNTV
QIASDIQKKMGVTSLAHLTCASSTKEEVLSVVDRLKAEGIENILALRGDIPEGLEFPETD
QYHYAYELIREIKKQGDFCIGAACYPEGHVENEHKEDDIAYLKQKVDCGVDFLTTQMFFD
NAILYNFLYRIREKGITVPVLPGIMPVTNSRQMTRICKLSGTVLPQRFHAILDRFGEKPE
AMKQAGIAYATDQIIDLIANGIDHIHIYSMNKPEVAAAIMTNLSEILR
>A0A196M8X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. TCM1|TrEMBL
MTLNDPAAPLYADLAGDCHVSFEFFPPKTEKMETQLWSAIETLTPLAPKFVSVTYGAGGS
TRERTHNTVARIAQETPLAAAAHLTCVAASKGEIAEIADAYWEAGVRHIVALRGDPPEAG
GRFEPHPDGYAGAADLVDGLMRQHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFAPETYFRFLDRTAAAGISADIVPGIMPVSNFAATQRMAAMCNTDVPSWMARLF
EGLDDHPAARQLVSATIAAELCRKLYEGGVRDFHFYTLNRAEHSYAICHLLGLRPNAAAV
AQSEKAA
>A0A067SU14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Galerina marginata (strain CBS 339.88)|TrEMBL
MKLSTQIEAQDASNPFYTFEFFPPRTDQGFDNLMSRISRLSALNPLAISVTWGAGGSTKD
RSLELAGLTQNSDVNTILHLTCTNMELGLVDEVLKAVKQQGIQNILALRGDPPRGEEEWI
ASDPRFTRAVDLVSYIRSVPEYSAWFCIGVAGYPDGYADNPVDEDIEIDRLKEKVDTGAD
FIMTQLFYDVDKFLSWYRKIRQRGITIPVIPGVMPIQTYSSFARVTKLCGTRVPESVSTE
LAAISHDDRLVKDYGVNLAVNIIKSLRVEGGINGFHFCTLNLEKSVQRVLETLGWAGSPS
TDQNKLIVEPPGTPSHPLPLADADSKLMILPLNAANSATLGLSTISTTEGEAGRGELNNA
ASWDDFPNGRFGDFKSPAFGNQDLWGGSGISRPEALAQWRNPKKAEDLTQIFLNHLHSKI
PTTPFSPTPLSPESLMILSHLEKLTQRGWWTVGSQPAVNGASSSDEVVGWGPRAGYVFQK
CFVEFFCSEQDVNAIEQRIKESGNGWVHYFAGKNQGECRSNVPDNGRNAVTWGVFPGQEI
VQTTIIERESFLSWKDEAFSIWSEWASFYRPGSEERELLEGVRNNQWLVSVVHHDYQNPE
ALWTFLLGHSKTNST
>A0A4Q5R6U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagaceae bacterium|TrEMBL
IKNRFDVDTVPHLICGGFAKEETENALIDLHFLGIDNVLALRGDPIKSEGQFQPHPDGHR
YASDLIKQVAELNHGRYHDHDEQYQPAGAEPVLCTDFCIGTAGYPEKHFEAPNLGSDIRF
LKEKVDRGADYIVTQMFFDNEEFFKFEKHCRDAGITVPIIPGLKPLTTKNQLTALPRAFF
LNLPEALTEAIHAAKDNAAAREVGIEWCLNQSRELMAHGVPCLHYYSMGKSEAIRRVAAG
LF
>Q220Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118)|TrEMBL
MTATPQIPLSFEFFPPKTPEGVEKLRLVRQQLYALKPEFCSVTFGAGGSTQEGTFSTVRD
ILTEGIGAASHISCIGATHAKVREQLAILKAMGVKRLVALRGDLPSGFGVGGEFHYASDL
VAFVRAETGDYFHIEVAAYPEVHPQARSPEADLQAFATKVKAGANSAITQYFYNADAYFR
FVEEADALGLSLPIVPGIMPIASSTQLMRFSDACGAEIPRWIRLRLQGFGDDAVSIKAFG
LDVVTDLCEQLRAGGAPGLHFYSMNQSAATLEVCNRLGQGPAD
>A0A833N4J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fluviispira multicolorata|TrEMBL
MTNILSKTPNGCCRSFRKSLANGEYILLGGSTGSLLYEKGIFINRSFDEVNLSQPDLVSQ
IHSDFIAAGAQIISTNTWGANAFKLKSFALENKSTEINISGAQIARKAAHNQCWVAGTMG
PLGVRIEPWGPTSLDEAKDVFKAQAEALIKGGVDLFIMESFADLYEIQQAIRAVRELGDL
PIIAMMSVNEEGHSLYGTEPEWYIRKLDEWGADVVGADGGNGPTPMLELLKKFKSSTKKP
IILCPNAGQPRMVDGRLIYMASPEYMGEFARQAFLKGARLLGGSSGTSPSHIKIMAGALR
QAKAFDQVEIKHNEIIDHKIVHPTTVPRVQQSNWAKKIADGQFVVCMELLPPKGLETEKI
IERSEICKKHGIDAINIPDGPRASARMSSLATACIIEREVGIESILHYACRDRNLLGIQS
DLLGASGLGIKNILCITGDPPKMGPYPNATAVFDIDAIGLVNMVTRLNTGFDLGGSSIGR
HTSMSVGVGANPVAIDLEKEKSRFRYKVEAGAEWAITQPVFDAESLFRFLEFSSQFKIPI
IAGIWPLKSIRNAEFMANEVPGVFIPNKILERMRKCKTADEQAKEGILIARELIEEIKSS
VQGLQISAPLGLVDFALKLL
>A0A852Z638|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolymorpha rutila|TrEMBL
MPAPAFEVVCEVEPPARPDLAHVRRQIDVLGPVADAFLAPDNHLGRATISSVAVAHEIQR
AGGRGLACLNARDRNLLGLRRDLLTAAAYGVERFVFVYGDKPTSGNRTGDLTVRAMLEEV
RRFAEEPELRAGGFRAGVAAGPGPLPAWKRAADFVFAQVGFDVAEQVRWREAHGPDCPVY
AGVLVLSSEAMARRLAASIPDLDIPEELIRRVGQDRQAGVEAACEQVERIRDSGAFDGVH
LVTGVRFRPMAEELTRRGFGKSGSSGLTEGVRAGRRPALPQDSGPGPGPAAR
>A0A7K4A8S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinaceae archaeon|TrEMBL
MKFREKLQSGKFVITCEVPPPKGTDTSYSIENASFIRELADAVNVTDNQCAQLHMSSIAF
STLLKQNGYEPIMQMTCRDRNRIGIQSDVLGAYGLGIRNILIMSGDYPTFGNQPGAKPVY
DLDSVHALNAISLLKKGTSLSGSNIAGPFDMCVGAVCNPVPEKKFQIMKLEKKVKAGAEF
IQTQAVFDVDMFSEFMDLIRDRGIDIPILSGIVPLRSVEMARYMNQNIPGISVPPEIIKR
MEYADDQIEEGIEITAEIIKCMKNISNGIHIMPIKSHRCTKNLLRRSNFL
>A0A7W3N321|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomonospora cellulosilytica|TrEMBL
MSSALPGRAPTIRELLAAGGKSFSFEFFPPKTEAGVRNLWRTIRELEALRPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVNHSVAELRNLIGRFASVGVRNILALRGDPP
GDPMGEWVKHPEGVEYAEELVRMIRSYGDFCVGVAAFPYKHPRSPDIDSDTRHFVAKCRA
GADYAITQMFFRAEDYFRLRDRVAAHGCDVPIIPGIMPVTQLSTIERSEQLSGAPFPPEL
AARFEAVGDDPEAVRRLGIEHAAALCQELLDQGAPGIHFITFNKSTATREVYRMLDVSAL
GGVASGSPASLAG
>A0A1J4N818|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides luteus|TrEMBL
MDLQQRIRDRAGEILLFAVTPPRVTTDPERVQQIAEVTLERIRPLEVDGLILYDIDDESD
RNPEERPFPFVRTLDPAEFLERNLAGLDVPAVVYRATGKYEEPTLRDWVKTQDPAKALSV
FVGASSGEKRVATSLRRAQEIRRETNPDLLLGAVAIPERHTAKGDEHLRLIAKQEAGCSY
FVSQVVYDVNAAKNLVSDYRYECETRGLQPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENELRHATDTLDASLEQAEATAIELMSFCRQLGVPFGINIESVSIRKVEIEASVRLAERL
RDKLER
>W0MPD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae CC1557|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLELE
NEVKVPAAPHLSCVGDSKDDLRSLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VKFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCESLLEGGAPGLHFYTLNQADPSLAVWNNLKLPR
>W2UH47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium MOLA455|TrEMBL
MSIDRPDLSFEFFPPKTEQGKIKLAKTRQELGKFNPEFFSVTYGAGGSTRATTADQVAAI
QADGFEVAPHISFGGNSETEVLELLNSYKASGVKHLVALRGDLPSGMGGAGQLVHANQLV
AFIRQHTGDHFDINVAAYPEIHPEAESYSKDVYWLGEKFKAGANRAITQYFYTADAYFKF
VDECAKAGIGEPIIPGIMPLTNYANLMRFSDSCGADIPRWLRWQLKERSNTMDDLVSYGI
DIVSELSQKLLDGGAPGLHIYTMNQWQVTSTLCRNLGFSDNH
>R8YPA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii ANC 4050|TrEMBL
MTKRTPISFEFFPPKTDGGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQSGANAGITQFFFNPDSYFYFI
ERLDKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>Q6CEM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yarrowia lipolytica (strain CLIB 122 / E 150)|TrEMBL
MSTITKLIAGLKPDEKFFSLEFFPPKTQNGMANFRARLARMAALKPLFITITWGAGGSTA
KKSLDIASECQSMGLDVCLHLTCTNMDPALIDQALEAASKAGICNILALRGDPPRGEEYW
QPASPEFQHAADLVKYIKKKHGNKFCVGVAGYPEGHVDGSDASHQDFHHDLPYLKEKVEA
GADFIITQMFYDDNKFLEYNKAVREFSPLLKNITIIPGLMPINTYTSFVRAARLSHASVP
PAILDRIQAVPTGNDQQVKDIGVEVVSDIVNDVYTKTNKTVRGFHFYTLNLERSVARILE
RSGFLTIEEDCAVEEATGSTASTTPNKTPLRRRSSATHRNRVVDDARHHPDAPKEEPDLT
TLALAIASGEGAVGREAVWDDFPNGRFGDSSSPAFGEIDGYGPSIHVPPARALELWGYPV
DDADLSKLFADTIVGKLPFMPWSDQTLSPETMLIQEQLMELNQKGIWTVASQPACNALKS
DDNIFGWGPKGGYVFQKSFAEFFISPEQWKKLKPLLDAQEDLVSYYVAKSDKLVDTNVSE
RASNGVTWGVFPNREIVQTTIIQEDSFDAWREEAFSIWSEWRALYKKNTASFKLLDKIIN
EYLLVTVIHHDYVEEDGLWELLGSV
>A0A5N7RPV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium SAGV5|TrEMBL
MSSSVSPGAAPAEAAPVFSLEFFPPRDSAAQEKLVRAAEQLHGLHPHFASVTFGAGGSTR
DGTMLAVSMLQKLDYEVAPHLSCIGSTAESLRDVLYTYRQAGIRRLVALRGDMPSGMGDM
GELRHARDLVDFIRRETGDWFHIEVAAYPEMHPQAQGPEADLDRFVEKMQAGADSAITQY
FFNADAYFDFVDRATAKGVLAPIVPGIMPITNFTQLARFSDMCGAEIPRWIRLRLASYGD
DRASIRAFGHDVVTELCQTLLDGGAPGLHFYTMNQADATQAVWKELER
>A0A1N6YZZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. RU33C|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVEQINDLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREIGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAIAQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A2H1YCP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum finnmarkense|TrEMBL
MKVTKHIEKANGKTLFSFEIIPPKKGNNIQDLYQNIEPLMEFNPPFIDVTTSREEHLYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFSKEETEYLLVDCHYLGIEN
VMALRGDAMSHQRYFEVSKGGHQYATQLVAQIKNLNQGKYLHDVIEANHKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVKHARKMGITVPIIPGIK
PISVKRHLQLLPQVFKIDLPQNLITEIEFCKNNQQVRELGIAWAIAQSQELLKAGVPVLH
YYSMGKSDNIKAIAKALF
>A0A6G4W6C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium camelthorni|TrEMBL
MTGRQRDEHPDGIDLPLDPQPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
VFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAINPFAPPYDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTFMQKARDLGYTEQCFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAIITRLEGAQDQKKEGKQLAIDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEIVETQSDLVK
TAH
>A0A6N2VJ74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerostipes caccae|TrEMBL
MKISELLKEKATISFEVFPPKNKEGDISSIYYTIEELAKLDPDFISVTYGAGGSSKGKTV
EIASAIKNKYQIESVAHLSCITSTKEDILTECRALKEHNVDNILSLRGDYPAGEEEKYRG
MDLEFHYASELNGFIRENFGDSFCLSGACYPEVHQEADCFRDDLEALKKKVDAGAEYLIT
QIFFDNSYYYRLVKEARKIGIDVPILAGIMPVTNAKSLLRTAKLCGCSIPFQLSTMIETY
YNYPEAMKEIGINYAAHQIIDLITNGVDGIHIYTMNKPEIAQRIFGNIPTVLKELNHD
>A0A853JKR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium callanderi|TrEMBL
MSSLLQQTLEAGKFAITAEMAPPKGTDFSHILEIADLLKGRVQGVNVTDYQSAAVKASSL
AMCVELEKKGLESILQMTGRDRNRIAIQGEMLSAGHFGVKNMLALTGDHTTTGDNPEAKP
VFEMDSVSILQTAEVLMSGQDLAGNELKGAPDFYLGACVTPVFDPIEVQLIKMRNKIKAG
AKFFQTQGVFDIEVMREFKELTKDMDCYVLAGIIPLKSAGMAKFMNRSVPGISVPDALIE
RLTEAEDKAAEGIRIAGEFVAQLKEEGVCDGAHIMAIGAEENVPKILDVAGL
>A0A7K1LMD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gramella aestuarii|TrEMBL
MKITEHLQAAKDKTLFSFEILPPLKGQNINSIYESIDPLMEFNPPFIDVTYHREEYVYSE
KENGLLEKKIVRKRPGTVGICAAIQSKYGVDAVPHILCGGFSKEDTENFLIDLDFLGIKN
VMALRGDAVKSETYFKPEKNGNCFAKNLVDQIYDLNSGKYLDEVIEKGHNTDFCVGVAGY
PEKHMEAPSIDKDIQRLKEKIEAGAEYVVTQMFFENDRYFDFVEKCRESGIDVPIIPGLK
PIATKKQLSVIPHRFHVDMPDCLIREVEKCKDNAAVRQVGIEWCIQQSKELIAGGVPVLH
YYSMGKSTNIQQIAEAVF
>A0A651G4U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinarimonadaceae bacterium|TrEMBL
MTFLPRASRSGSPFRSVSFEFFPPKSAEMEATLWSSIERLAPLGPTFVSVTYGAGGSTRE
RTHATLTRLVRETALKPAAHLTCVAATREEVDEVVEGYRDIGVRHIVALRGDPVAGPGTP
YAPHPGGYATSWDLIAGIREIGDFEISVSAYPEKHPDAASLDADIDALQRKVDAGATRAI
TQFFFDNDVFFRFLDKVQARGIDIPIVPGIVPVQNFKQTAGFAARTGASVPAWLAARFEG
LDDDVQTRKLVAAAVAAEQVIDLIDRGVEDFHFYTMNRADLVYAVCHLLGMRADRPLQRA
AA
>A0A1V8TRV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rachicladosporium antarcticum|TrEMBL
MSRPNPTAPSTMADDRITTKLAALPRDATYFSLEFFPPKTSQGFSNLHARLARMAHSLRP
LFVNVTWGAGGSTSAKSLALAELTQRSLGLTTCLHLTCTNMSRKLIDEALEQAKVLGVRN
ILALRGDPPRSDEYRAEGAAVGEDEDDSNVEFTWAVDLVKYIKKTYGDYFCVGVAGYPEG
HADTSHPEHQGVGLDLPYLVEKTSAGADFIMTQLFYDVDAFLAYETTLREHDSGIFKEIP
IIPGLMPVQSYQILRRTTKLSHAKIPPNVLKRFEAVKSDDEAVKRVGVDVLSEFVDKIKA
RPDVRPRGFHFYTLNLEKAVAHILERSSLIPPYTPTIIEKNGFTSPEDAIAEHESSASAP
TNGHGTRTRRESSTANSGPRNRVVVSRTRASSTSSTRTSAFEAPEDEAGVPRDKINSRAN
TLAISEGEGALGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHVSIAEATRLWGHPSST
ADLSEIFRRHLEGEVDAVPWSEEGLSPETLTIKSQLLALVQKGWWTVASQPAVNGVRSTD
PIFGWGPRNGFVFQKPFVEFFLPAQDWKRLQPVLDEDPQITYFASNAAGDSAASDEESVN
PVTWGCFTGKEIVTPTIIEGVSFRAWCEEAFGIWGEWRGVYGKGSPSSKVLDQVRKEYWL
VNIIHHGYLEPEALWETLVKA
>Q1LJ15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>K2NR83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosipho africanus (strain H17ap60334)|TrEMBL
MKISQIKDFFISIEVIPPLRGHSADNLYKAIDKIMPYNPAFISVTKHPPELEYYEIDGQI
LKLPKVKRPGTMGIVAALKMRYNVDVVPHLTCIGNSKFELEELLIDLDFLGIDNVFVIRG
DKKKNVIKKEWQYDYAYQLVQQISDMNKGKYLYQTAKKTNFCIGVAGYPEKHYESPNLKT
DIKYLKRKIEAGAQFVITQMFFDVEKYFNFVKLLRDEEINVKVIPGLKPILSYKSALKIP
GTFYVDIPEELIEKLDNARTPKEEFWTGVKYTIKLIEKLKENNVPGIHFFTMSNTDAIVE
ILKHI
>A0A1V8SUR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rachicladosporium antarcticum|TrEMBL
MHITKKLAASHAKGEPTYSFEFFPPKTSQGVQNLYDRMDRMHGFGPAFIDITWGAGGRHS
QLTCEMVKVAQSVYGLETCMHLTCTDMETSKIDEALKEAYNSGCTNILALRGDPPREQEK
WEQAEGGFRYARDLIKYIKTNYGDHFDIGVAGYPEGCDETTGSEEHIPYLKEKIDAGGTF
IVTQMCYDADIFIDWVHRCHAAGIPESVPIIPGIMPIHTHASFMRRATWTQCHIPPEWHE
RLEPVKNDDVSVREVGKELVADFCRRVLDSGTTMHLHFYTMNLAVATRMVLEELAVTPAS
NEHNPLLKPLPWRQSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAF
GELDTYGVGLKGTNEENRKLWGTPESNRDIADLFVGYMKGSVKSLPWSEAPINTEANVLQ
SDLVDLNGRGLLTINSQPAVDGAKSNHQDYGWGPKNGYVYQKAYLEVLVHPDLIETVISR
MDRDEDITYYAVNSSGSLRTNVPVDCGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFY
HLGSEWAKCYAEGSASKTLIKDVVDNWYLVNIVHNDFRQARGIFPLFEGLSAPGVSVKEQ
ANGNGYVNGHVNGGAENSDLAVRNKLETNGVYDGNNAVNGADHANTTNGQKCEVEA
>A0A017SLV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus ruber CBS 135680|TrEMBL
MHVKEKLAQNEANGKTGISFEFFPPKTAQGVQNLYDRMDRMHSLGPEFIDVTWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAALHAAYKAGCTNILALRGDPPRDKEH
WEVADGGFSYAKDLVKYIREKYGNHFDIGVGGYPEGADDNSDVDLLIDHLKEKIDAGSSF
VITQMFYDTDIFINWVKKCRAKGITVPILPGIMPIQTYAAFLRRANWTKAHIPQDWLDAL
EPVKNDDAAVRDIGKTLIANMCRRLLDSGLIKHLHFYTMNLQQATQLVLEELNLVPSEET
PLPKPLPWRPSLGLKRRGEDVRPIFWRNRNSSYIARTQTWDEYPNGRWTDSRSPAFGELD
AYGVGLKGTNEQNIKLWGEPKSVQDITTIFVRYLKGQLARLPWSDTAISGEADAIMENLI
NLNSRGFLTINSQPAVNGAKSSHPVHGWGPKNGYVYQKAYLELLVPNDVVDELISRIEKN
ADLTYHAVSKTGGLRTNTLDSPNALTWGIFAGREVIQPTIVETVSFLAWKDEAYRLGEDW
AKCHDAASPSRKLIQNLVDNWSLVNIVNNDFHNTYDIYKLFDGLNVKDLDVEVSGDAPVP
QQNGASAKAAAAN
>A0A1G0KWG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFOXYD12_FULL_61_37|TrEMBL
MSQSISIELFPPKTEAGMEKLKEAVRELSLLGPEYISVTYGAGGSTQGGTFATLDWLVQQ
GMETAPHLSCVGSSREEIREILGRYKAQGIRRIVALRGDLPSGAGLGGLGELNYANELVA
FIREAFGDHFHIEVAAYPECHPQSANLQADLNNFRRKVQAGANGAITQYFFNPDAYFHFV
ESCAGMGLALPIVPGIMPITNFSQLARFSDACGAEIPRWVRKRLEGFGDDLESIRAFGLD
VVTALCERLLQGGAPGLHFYTMNQSGPTLEIMRRLTG
>A0A7V0JWK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
PLAIAKILIDNGVEPVYQITARDRNRLALQSELLSASILGVENVLCLTGDAISQGDHPRA
KPVFDLDSVQMLYTASLLNQGKDLAGKKLNRPTNFFLGAACSPNADPLEPEIIKARKKIQ
AGAKFFQTQAVYEPAKLKQFIKILGEDVFILAGIVFLKSAKLAKFMNENISGVEIPEEII
SELESASDPVQKGIEITARLVVELKEFVDGIHLMPLGKAEVVPEILAKAGFAPLQEEVS
>A0A7D7N910|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria shayeganii|TrEMBL
MKKNTLSFEFFPTRTPEGREKQKITRKQLRQYRPAFFSCTSGAGGSTRDGTLQAVNDIMA
EGTAAAPHLPCVGMNEAELSDILHIYKNMGIRHIVALRGDIPSGMGAGSSGLRYANELVE
LIRRDFGDWFHIEVAAYPEFHPQARSAEDDINHFVRKVKAGADSAITQYFFNPDAYFRFV
DDVRGRGVEIPIVPGIMPIASFSKLARFSDTCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCEHLLEQGAPGLHFYTLNQAGLVSTICQRLGY
>A0A8I2KN61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas maricaloris|TrEMBL
MALTLQEKIIDPNQGVYLIGTTPPKIGTDPEQLKSIAAKLLGRLHEIEYDGVIIYDIQDE
SSRTQVPRPFPFKHTVDPCEYSQLIRELSHLDVITYKSVAQRDSEAFGNWLSSTKQQYGL
NNLVLVGSPSSQGDIKLPLSEAYKVLKHHQDDFFLGGVTIAERHASKRNEHERLIDKTEQ
GCQFFVSQAVYDAQATIDLITSYARTCKQQGQTPKRIILTFTPCGGEKTLQFMEWLGISV
PEATKWRMLDADNTLSESIRICRENLDQILKSCSHLDISLGLNIESLTNRKEEIDASINL
YRLLKATMELCLAEKQIA
>A0A7W0J185|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MRIAEKLAASVKGVSFECFPPKTEKGRHNLYAALGGLEKYRPLFVSVTYGAGGGNKDTAV
GTVLSHKKDFSFEVTPHLTCIGAPVGEINRILDTYKAARIIENAGIL
>A0A7C1MWU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MTLREKIKSGKFIVTDEVGPPKGIETKEILEDCNLIKNRVDAINVTDLQSSVMRLGSLAV
SSILKQNGFEPVYQITCRDRNRLALQSDVLSAASLGIENLLLLTGDHQSLGDHPEAKGVF
DLDSVQLLEAVKGLEQGHDMAGKELKGELPKFLKGAVVNPGADPLEPQILKMKKKIEAGA
EFFQTQAIYEVDKFAKFIDEVKDFGVPIFAGIVLLKSAGMARFMNKNVAGIHVPDDLIVE
IDGAEDKSAKAIEIATRLIKELKPLCQGIHIMSIGWDKKVPRLLDAAGL
>A0A5R8KDD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phragmitibacter flavus|TrEMBL
MHVQDIFATQRPTFSFEFFPPKTEAASLALYETISELEAYKPAFVSVTYGAGGTTRELTH
DLVVRINQSTTLDAVPHLTCVCHGDSDIEAILERYAEAGVSNILALGGDPPKNLEGYVRA
NDAFQHAADLVKFIRNFKGHSDSRGFGIGVAGFPEGHPGTPNRLMEMDYLKAKVDAGADY
ICTQLFFDNRDFFDFRDRCHLAGIHVPIIAGIMPVTSASGMQRMAELAAGARYPAKLLKA
IARCGKDEDAVQRVGVHYATEQCADLLDNGVDGIHFYTLNKSGATRDIYASLGLKDSHSL
QAV
>A0A2N6EBZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MSKLQQQLDSGEFVVTAEIAPPKGTDVSGALAGARALNGVTAVNVTDNQGANMRMTPLAV
AALLVREGIEPILQLTCRDRNRLALQSDLLGAAALGVENLLLLSGDHVRFGDHPGAKAVF
DLDSVQLLQVVNGLSGGQDMAGKSLAGSPAFFAGAAVTPEAEPFELMFQKFSKKVESGAR
FFQTQAVYEPARLEQFMDEARPLGTPILLGVLLLKSARMARFLNEHIPGVRVPESLIARL
EGAARPLDEGVAIAREMVGHAREHCQGVHLMTLGHEERIPEILG
>A0A1Y1YRJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clohesyomyces aquaticus|TrEMBL
MHISQKLAQSRAEGKVTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDVTWGAGGHLS
HLTVEMVKVAQSAYGLETCMHLTCTDMEKSKIDDALRDAYQAGCTNILALRGDPPRQKEK
WEATKGGFHYAKDLVRYIRERYGNHFDIGVAGYSEGCEDNDDVDVLIDHLKEKVDAGATF
IVTQMFYDTDLFLDWVGKVRAKGIDIPIIPGIMPIHTYAAFMRRANWTKCNIPPHWTKAL
EPVKNDDVEVREVGKDLVAEMCRKLVDAGILHLHFYTMNLAQATRMVLEELELLPDLESP
LEKPLPWRPSLALNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDARSPAFGELDA
YGIGLKGTNEQNIKLWGSPTSIQDISDLFVRYMGGKLDSLPWSEAPISKEADTIKNDLID
LNRRGFLTINSQPAVNGAKSYDPIYGWGPRNGYVYQKAYLEILISPEFIAEVITRIERDP
DLTYYAVNKEGDLKTNSPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQEW
ANCHSSVSPSRYVIEDVVDTWYLVNIVHNDFHVEHGIFPLFDGLKVKDMEKPLHSNGVIN
GHSERNGEPDQKVQNGINEKSIVDDIKSAASAITNGLSGLTVAN
>A0A1F8N8S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_60_9|TrEMBL
MRIVDRFRTQQKPCFGFEFFPAKNSKAQENLDRTIDKLAAFAPDFVTVTFGAGGSTRVGS
RQLAARLKHEKELEIIAYFAGYGLGPQEISEALTGYSENGVENILVVRGDPPRDPAFRPH
ADSMVYASDLLDYIRPRYSFCLGAAGYPEGHVQSESPERDADFLKRKVDQGAEYILTNYF
YDNRFFFDYVERCRARGVNVPILPGVMPILSLKLAESIAATCGASIPEAVRSKLAAIPEE
DKKAAADYGIELAERQCRELLAAGIPGILFYTMNRWESVSEIVNRLRACGML
>A0A4R0RSQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steccherinum ochraceum|TrEMBL
MKFAEKVADYNGSRPFFTLEFFPPKTDQGFDNLQSRIARLSALNPLAVSITWGAGGNTME
RSLELAGLTQSEHGIDTIMHLTCTNMEKGTVDKALQAAKERGIESILALRGDPPRGQEHW
IPTDPRFTHGVDLIRYIKSTPGFAHFSVGVPGYPDGHTESEASEDDEIQYLKDKVDAGAD
FIITQLFYDVDGFLRWQKKVRAKGIQVPIIPGIMPIQTYGSFMRLIKLCGAKVPHSLMSD
LVPIRHDDQRVKDYGVTLAVKMIQRLTGEGEVPGVHFCTLNLEKSVQRVTEGLGWTGAQS
RVINKLITDTPVQSSHSLPAESTRLIDPHLAADSATSGLGVAGLPQQEAGKGELNNASTW
DDFPNGRFGDFKSPAFGDPNPWGASNISRNQALNEWGHPKTVKDLTDMFLRYLHSKLAST
PFSPTPLSPESMMIFRHLERLTQKGWWTVGSQPAVNGAPSTDEVVGWGPKGGYVYQKCFV
EFFVEEEDVDKIEKKVAEKGLGWVDYFAANFNGDCRTNVPDGGRNAVTWGVFPGQEIAQS
TIIERESFLAWKEEAFSFWSEWASYYPPDSEERKLLDRVREKRWLVSLVHHDFQNADAMW
SFLFDGKEAVVDGN
>A0A419DXQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MTLSEKIKSGKSLLTTEIGPPKGIETKTILEDAELVRARVDGINVTDLQSSVMRLGSLAV
CSLLKQKGFEPIFQVTCRDRNRLALQSDILSAAALGIENILVLTGDHPKSGDHPDAKPVF
DLDSVQLLQVIKGLESGQDMNGNKLEGVLPKFCLGAVVNPGADPIEPQIIKMEKKIEAGA
VFFQTQAVYDVRKFEVFIEKTRHLNTTILAGVVLLKSAGMAKFMNKNVAGVSVPDSLIAE
MQQAQDKVKASVKIAAGLIKELRPMCQGIHIMPIGWDKVVPMVLDEAGL
>A0A2D6DJC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium|TrEMBL
MASKLLFGVSMQVSFEFFPPRDNAGQNSLDNAVQQLQVWQPQFASMTYGAGGTSQQASFA
GAQKLLAQELATASHITCVGADRETVQATAKQFVAQGVDHFVALRGDSPDGPYVPHPQGY
AYANDLVAGLRDWFTGTISVAAYPEIHPQALSGAKDLAFLKAKMDAGADQIITQYCYDTD
TLLAFAENLQKAGITQPLLVGIMPIHDIAAVQRFSARCGATVPQSFGDRFAGLEQAQDKV
KLAIEIAAEQCRQLIDNGLDQFHFYTLNRSTLTAGVLASLEQPPVNLALSA
>A0A1F3Z995|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RBG_19FT_COMBO_58_11|TrEMBL
MSDKRTFSFEFFPPKTPEGMEKLRATRQQLAQLKPKFFSVTYGAGGSTRDRTLEAVMEIQ
ASGSASAPHLSCIGSTQESIQEILDLFKAKGIRHIVALRGDLPSGMADPGEFRYANELVA
FIRKQTGDWFHIEVAAYPEFHPQAKNAQDDLANFKRKADAGASSAITQYFYNADAYFRFV
DDCVAMNVTIPIVPGIMPITNCAQLSRFSDACGAEIPRWIRKRLEAYGEDLDSIRAFGLD
VVTDLCDRLLQGGAPGLHFYTLNQAGPSSTIWQRLGL
>A0A402C0K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus wratislaviensis|TrEMBL
MTRTPSIVDRIRSSGDGRVPFSVEFSPPRDEAAEARLWRAVREFERMGPAFVSMTYGAGG
STRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRGISNILVLRGDPPGD
PLGEWEKHPQGVEYAEDLVRLVRDLGDFHVGVASFPEGHYRAPDLAHDTRYLVSKLRAGA
EYSITQMFFDVDDYLRLRDRVSAYDAEQGAKPIIPEIMPITSLGSVRRMLELSGSSLPAH
LEKRLATAAGDGPEENRAAVREIGIDLATEMSERLIAEGAPGLHFITLNFARATSEVLAR
LGDKVGSGVADPSPVTPAPVS
>A0A8D4RTA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRSDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A6G8NNN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia sp. SBC1|TrEMBL
MKPIELSFEFFPPKTQEGIEKLRATGAQLKTLNPKFVSVTFGAGGSTQQGTLDTVVEMMK
QGLEAAPHLSCIGSSKDSLRGILGAYREHGIRHIVALRGDLPSGMGEVGELRYASELVGF
IRAEHGDWFNIEVAAYPEYHPQARSPKSDMDNFVRKVQAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPKWIARRLESFGDDKEAIRAFGLDV
VTGLCERLVKEGAPGLHFYTLNGAAASKTICERLALPGK
>A0A8H9L5J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus arenae|TrEMBL
MTRVSVELVPRSRSGLRAEIAEVAGALSGVDTVNVPDLTRYSLRSWVGCGFARPGFAAIP
HLRAVDFNPREPLPFLPLLEEHGIREVLVVTGDAPIDMSAKVYDQDAVDLIRRLNRDAPH
LRVYAGLDPYRQSFVRERDYLERKLDAGATGFFTQPFFDLRLLDTWADLLPDGTDVWWGA
TSILTEASFNYWRARNHAVFPRTFTPTLDCNRAFARDLLTFAREREQHAYFMPVKVNVLE
YLGGIL
>A0A7X9BJS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MKISKIIDKKKLLISFEIFPPKQEANFDSVMQTALDLGGLNPDFISVTYGAGGTTRSYTA
ELASSLQEKTQIPSLAHLTCVGSGFSDIQSIIRELKEKKIENVLALRGDYPQGADASDLP
GDCAYASDLVRILKKEADFCIGGACYPEGHPESENRLEDLQHLQYKVDAGLDFLTTQMFF
DNEVLYSFLYRMQSKGMKLPVFAGIMPVTNAKQIKRMITLSNAHMPQKLLAFVDRFQDNP
GAMMQAGIAYATEQIIDLIANGIRGVHIYSMNKPDITAAIMHNISHIVEAVNAEAHV
>A0A7K5SDE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lanius ludovicianus|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLRDKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A0L8BEM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer adhaerens|TrEMBL
MSPDYNPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNVLCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHETLPTDALVASRMEHIREGKEENQQEMAEAAAH
HPH
>A0A3N6RJV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica cretica|TrEMBL
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNAICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAYGIHFATEMCKKILAHGITTLHIYTLNVDKSAIGILMNL
GLIDESKITRSLPWRPPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYSTLSDYQFMRPRARDKKLQQEWVVPLKGIEDVQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TLVEKSKAFPSITFMAVNKAENWVSNIGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDNPSRKLLEEVKNSYYLVSLVDNDYINGDIFSVFA
>A0A564TWG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus constellatus|TrEMBL
MQDLAPHFISVTASNRKFNIEETTVRLADFIYNDLQIPTIAYLLAVYLTKEMVSDTLEAL
DRVGVHKVLALRGDIFPNMEPKKDFTYATDLIEYIKEQAPHFEIIGACYPDSPDRVSDIK
NLKKKVDAGCSSLVTQLFFDNERFYDFQERCTLAGIEVPIHAGIMPILNRNQALRLLKTC
ENIHLPRKFKTILDKYEYDPESLRAAGLAYAIDQIVDLVTQDVAGVHLYTMNNSNTAHQI
YQATHTFFNNKVSS
>A0A2E7YY57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pelagibacter sp|TrEMBL
MEYQSLLHKKLLDGNFVYTAETTPPDSADQEVILTKTKPLKYIADAVNLTDSPGAKVHMS
ALTAAIILAQNDIEPILQLTVRDRNRLALQGDLVGASALGVHNILCLSGDDPKIGDQPET
TAVNDIDSLTLVATADLMRRKGKFPSGRLIEPPPKLCIGGAEVPTEGKPNTEKILNKIKT
GINFFQTQYVFDKKILKEYMKVLDDVGILEKTFFIIGLGPFTSAKSAKWMNNNLFGVNVP
EKIIKRLEQSKDEKEESKKICLELIHHFKEINGVMGVHLMGHNKEEIIAEIIQESRKNNN
>A0A2U9DXY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIIALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A098MHP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Lai|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TAQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>R6EIS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:709|TrEMBL
MKITEILNESKKPFPSIEIVPPLNGMSKDELLRTIRSFMEFAPKYINVTCHRDEYAFRKE
ANGTYSRHLVRNRISEVAVCAAIISEFDVNVVPHVICGGASAEELESDLYNYRFLGISNI
MALRGDSITGEKRFVPHPEGYAHANELVEAIRHFDEQTGESFCIGVGGYPEKHFECANIE
TDIENLKRKVDAGADYIITQMFFDNKVFYRFVDLCRKAGINVPIIPGLKPISTARQVALL
PQSFSLDIPKELTGAIAQAGDDKEEVYRIGTQWCAAQCKDLLAHGVPAVHFYTMGKPRNI
TEIMRECF
>Q7VHW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter hepaticus (strain ATCC 51449 / 3B1)|TrEMBL
MYDIESLIEQLHSTEPFLSVEIAPSISGRFDENLLEDLKTLKLAHAFVCTDSPLARFKPS
SILSSLKFQNALQKPVICTISMRDRNSIALCGDILSVNELGLRTFLTLTGDSIKNGDCLQ
SKGVFEDNSLKLGHIIDELNCGRALNGKSLKENIKRIYNFQVINAYANNPLSLKNKMRKK
LSSCEIHALFTQPVYSLNAAEFLLQSLEEIKSECNIKSALVLGFFPVLSYKTALFLRDKL
PGVYIPNEWVQKLEKAHNKGKDEENKVGLEISHSLFMELKSVHNKFHFMSANKPSLVKEF
A
>A0A554H0B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ST1|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>A0A1Z5TNJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii EXF-2000|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMSYDAEIFIEWAKKVRAAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAELFVKYMSGKVETLPWSEQPISPESNVL
TNDLVNLNSRGLLTINSQPAVDGMKSSHPVYGWGPNNGYVYQKAYLEVLISPSLITELIR
RMDANADITYYAVNNSGELKTNAPQDGGPNAVTWGVFPGKEIVQPTIVETISFLAWRDEF
YHLGSEWAKCYDEGSQSKNLIKEITESWYLVNIVDNDFRNERGIFPLFDGLKVQGVEPTA
AAVNGVAPLVNGDAQHGDVEKKQGAQKPEVNGVPDKNNAVNHADGSAVNGHVKN
>A0A618PM28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRV
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7S3RLW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strombidinopsis acuminata|TrEMBL
MPYADDKKISDLIATTKPGWFSFEYFPPRTDEGVENLRKRIVRMKNLNPMFTDFTWGAGG
STSELTLTLTSAAKNEYGCVANMHLTCTNQKAEMVGDALTKCKELGVRNIVALRGDPPRG
SEKWEATEGGFNCALDLVKYMRKEHGDYFAISV
>A0A761KRN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERAGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A857C6S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stappia indica|TrEMBL
MSSPERFRRFELDQGTGVSVSFEFFPPKTDKMEASLWSAVQRLEPLGPSFVSVTYGAGGS
TRERTHRTVERMLTETRLAPAAHLTCVGSSRDEVDEIVRAYHEIGVRHIVALRGDPLEGL
GAIYHPHPDGYAYASDLVAGIRRVSDDFEVSVSAYPERHPESPDWSAEIDNLKRKVDAGA
TRAITQYFFDNDLFETFMEKVRAAGIDIPIVPGILPIVNFETTMVFSAKCGTSIPHWLAR
RFAGLDQDAETRKLVASAVACEQVLDLVDRGVTNFHFYTMNRADLTFAICHMLGLRPAPL
EQQAA
>A0A8E1ZP48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. SwsAc2|TrEMBL
MSLLAQYFARQQFCVLVEYLSAHQAQWSVKTEFSGFPAAMTLADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDAKTQGQKNLLLLTGDKLKQHCYSHDLEPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMAAL
QDAHAFLARYQYAQKILACVMPLTLARAKFMLKHKVAGIVITPHMLQVLQQEKEQGLSDG
VYVRCALQILMCRHLGFAGVHLSACHQPEEQSLLERYIEEYRHLSFAECERLWNTLWQVQ
TGTEFHPKLAYYSRPATSSQIIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDRTKANN
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTAILKEKLIPTVSIAVRGTSSWKNWYVESAD
>A0A5Y4CCF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQTDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5Y4CCF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella choleraesuis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQTDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A436LWF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.001.01.1.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A2D5FHF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haliea sp|TrEMBL
MTAISFEYFPPKTPEGRSKLLESTTPALQALDPAFFSVTYGAGGSTRDNTFGVVKALREQ
GLDVAPHLSFGADDAESMAALLERYRELGVTRLVALRGDIPSGMGGSGQLVYASELVAFV
REHTGDHFHIEVAAYPEIHPQAESYQKDLHYLKAKLDAGANSAITQYFYNVEAYFYFLDQ
CAAIGIDKPIHAGIMPITNFNNLARFSRNCGAEIPRWICKRIEGYGDDQESIRKFGIEVV
TQLCQTLVDNGAPGIHFYTMNQVEPTREIYRNLGL
>A0A0C3D2I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scleroderma citrinum Foug A|TrEMBL
MKLTDKIEAHCAAHPFYTFEFFPPRTDQGFENLISRISRLATLNPIAISVTWGAGGSTKE
RSLDLAGVTQVEHGIDTILHLTCTNLVPGLVDDVLRAAKTRGIQNILALRGDPPRGQEHW
TPIDSRFSRGVDLVRYIRSSPEFSPHFCIGVAAYPEGHPDNQVDDETNFDILKEKINAGA
DFIVTQLFYDASRFLEWLERVRLHGIYVPIIPGVMPIQTYSSFLRVVDLCSIQIPPSIMA
DLEPIRHDDQLVKEYGIQLAIDIIRKVTDSGATRGIHFCTLNLEKSVQLVVERLGWAGGS
PIVRNRLIADSPAPMPPRSDLVVTPTIATTTAAVALTFRPTVECEPPGRGELNNAATWDD
FPNGRFGDYKSPAFGAQDQWGGLGLSVHVVNPDWGHPETTEELTNLFLRYLNSQVSSTPF
SSSPLSAESQTILPQLKALTTKGLWTVCSQPAVDSVESTDEAFGWGPRGGYVSQKAFVEF
FAEEDAVDAIEKNIKLKGDGLVHYFAANILGDLRTNVPEDARNAVTWGVFPGKEIVQTTI
IERESFLTWKEEAFSIWAEWASFYPPGSNKRTSLDTVRKSRWLMSILHHDFKNSRALWDL
IENSL
>A0A378E797|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae subsp. rhinoscleromatis|TrEMBL
MSFFHANQREALNQCLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A2E7C2G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haliea sp|TrEMBL
MPTISFEYFPPKTADGKTALLERTTPALQALDPGFFSVTYGAGGSTRDSTFGVVAALRER
DIDVAPHLSFGGDGEDTIRDLLQRYREMGVRRLVALRGDMPSGMGGASQLVYASQLVSFI
REHTGDHFHIEVAAYPEIHPQAESYDSDLRFLKEKLDAGANSAITQYFYNVESYFYFLDQ
CAAIGIDKPIVAGIMPITNFANLARFSRNCGAEIPRWICQRIEGFGNDQESIRQFGIDVV
TQLCQTLLESGAPGLHFYTMNQIEPTRQIRNNLGL
>A0A133ZY86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoanaerobaculum saburreum|TrEMBL
MENIRDYLKNNVLLFDGAMGTYYDELTDDGIGCELANIKNPELIKGIHNEYIEAGAKAIL
TNTFSVGIDVFNGDRNLQKEVVVAGIDIANEAAKDRAYVFADIGPIHTGSNELAFEEYKV
LIDIFLEKGVKNFLFETRSSTSGMVLSAEYIKEKCSDAFITASFAVMPDGYSSEGYQYNA
LFAEITNSGVFDAVGLNCVSGANHMAKLLKDVDTKGLYLFAKPNAGYPVVRDDRVYYSSL
ANYFANQIEDILELGVNIVGGCCGTTPKHIELLKKSMSGKLIKPRRAVKSEKSTAQNIRV
NRFKEKLDLGQKPIAVELDSPIDTNITKFMDNAKKIKAAGADIITIADNPIARARMDSCL
LACKVRNELDFDVLPHMTCRDRNVNASRGLLLGANAMGVDNVLVITGDPIPNAQRDEIRS
VFEFNSVKFANFINSLNNDVFESPMNICGALNVNSRNFSAELKKAVRKQENGVKVLFTQP
VLTKRAIENLKTARENLDIKIMGGIIPIVSERNARYMQSEVNGIYITDDIVEKYIGKGRE
EAEEIALSMSKEIANEIYDLVDGYYLITVLNRVSLMERLIKTVKKVCDNR
>A0A7X7CF92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
SDLIDNGIDGIHLLTMNRPKSSKEILENVGVL
>A0A1T4YW48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina newyorkensis|TrEMBL
MMSLLEKLQTNVLTADGAMGTILYSYGIDYCYEELNIEKPEIIEKIHHDYIEAGADIIQT
NTYSANAVKLARYGLENRVTEFNKAAIQIAKRAAAPGGQFVLGTIGGLRGIRKSDASLDE
VKQVVLEQANALLTGDPDGLLLETYYDFEELSSVVSTLRQITDVPLIAQVSMHDPGVLQN
GLSLNDALHQLESLGASIVGVNCRLGPYHTIQAFENVKLPENAFLSAYPNASLLDVEDGR
IVYESEAEYFGRAAVLLRDQGVRLIGGCCGTTPKHIKAAKTRLAGLSPITKKVVEPTKPI
VIQEAGPVKHQPLHEKAKTERTVIVELDTPRHLETEDYIKGANLLYDAGVDAVTMADNSL
ASPRISNMAMGSIIKMQHNIRPLVHLTCRDHNLIGLQSHLMGLDALGIHDILAVTGDPTK
VGDFPGATSVYDVSSMELLQLIKQLNEGISFSGKPLRKKANFSVSAAFNPNVRVLDRAVQ
RLEKKIEAGADYFITQPVYTKEKIIDVYEATKHLDTPIFIGIMPLTNIRNAEFLHHEVPG
IKLSDEVLERMRACGDDRAKATETGIQIAKELIDTAAQYFNGLYLITPFLRYDMTLELHD
YIKQIDKQKESELSHAETSY
>A0A7C6ZZR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
AGGSQRGRTVEIASKVKNHYGIESMSHLTCVGHSVEEIDRLLETMKEENISNILALRGDP
PADDPDYDFGKGAFRYASELIAHIRKEGDFCIAAAAYVEGHVESKRLSEDRRHLKEKVDA
GVDFLITQLFFDNRLYFDFIEKCAQIGINCPIIPGVMPIFSANIKNMTAKSGCSIPARLV
LMMDKYQDNPEDLRKAGEEYAGKMIRELLDGGAAGVHLYTMNRLESTIEILKIAGIR
>A0A7X4AZ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriia bacterium|TrEMBL
MKIGHMLTTGSPTVSFEFFPPKEEDGFGPLFETIDALRPLSPSYVSVTYGAGGSTRHKTV
DLVKRIKRDAGIEAMAHITCVGSTREHIADVLDSLEADGIENVLPLRGDPPRGSDRFEPV
PGGFRYANELVGFIRQRYSFCLGAACYPETHPEAASPEDDLANLKRKVDAGADFLITQLF
FDNDDFLRFRDRAVGAGISVPVLAGIMPVRSLSQTRRFATMCGARIPAELLARLEAVQAN
PAQVRAVGIDHATAQCRHLLAEGVAGLHFYTLNHSTATQAIYRRIRDQLGR
>A0A7W4PPC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconacetobacter takamatsuzukensis|TrEMBL
MSLPQPPGPGLSFEFFPPKTPKMAEALRQTASVLAPLRPRFISVTYGAGGSTRDRTLQTV
AELVRDTDVPVAGHLTCVDATRAEVDAVARAYWNAGVRHIVALRGDPSEPGTPFVPHPDG
YAGAIELVAGLRRIAPFEISVAAYPETHPAALSPAADLDHLKAKIDAGATRAITQFFFEA
ETFLRFRDRAAAAGIATEIVPGILPIGNIAQAYRFADMCGARVPDWMRRLFDGLDDHPGA
RAMVTTAVTAQLCRRLRDNGVTDLHVYTLNRPDAALALHRLLATDAAP
>A0A7I0HV64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira bouyouniensis|TrEMBL
MHISQILGKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRHLTH
DLVVKLQEETGLTIVSHLTCVGSTKDEIGEILKRYDKSGIHNIMALRGDPPKGQQDFQKT
DHGFAYAGELVGFIKKEYPNMGIGVAGFPEGHPSTPNRLKEIEYLKWKVDQGADYICTQM
FFDNNHFYDYVERCEIAGIKVPIIAGIMPVTSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDSYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRKIYESLGIRNFDRIV
>A0A3S2CX17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.001.01.1.1|TrEMBL
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A2W5M1A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter denitrificans|TrEMBL
MPPISFEFFPPKTDEQRATLEKTVAALRPRQPQYVSMTFGAGGSTLSYTLDAVRELHLRH
GLDAAPHLSCMGGSRAEIRELIETYRALGVKRIVALRGDLPSGMASFGDLRYASDLVEFI
RAESGDHFHIEVACYPEVHPQAADAHADLMHFKRKIDAGANGAITQYFYNPDGYFRFVEA
AQRLGIDAPIVPGIMPISNFSQLKRFSELCGAEIPRWLAKRLASYGDDADAIRDFSTDVV
AQLCRTLLERGAPGLHFYTLNRARPTLSVLDRLGAPD
>A0A353M9E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
MAAEKTQLHNRIESGKQLLLAESSPPKGADPAALRDLARTLAGKVHALGVSDNRDGVHMS
ALAAAALIGAEGIEPIVHMTTRDRNRIALASDCLGAQAMGIRNLLCTTGTHQTLGPCRSA
KNVFDVDSIQLLGICNSLGVDASPLGEDSFEGAGPLCLGSTASPFADPREMQVIRLAKAV
AAGSRFVITQPVFDLERFALWWEEVTKRGLHEKVAIIAGIRPLADADHALAYAAKRPSPM
IPAAALERISAAGDKKGQRAAGIEIAVETVQRLAGLKGLRGFELRVDGEVDIAMELLEKS
GLRID
>A0A1I1BEK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. NFR07|TrEMBL
MDENTTNQRLKISFEFFPPKSEEMEAQLWDTVERLALWQPEFVTVTYGAGGSTKEPTLAA
VQKIVGDTSLPTAAHLTCVDASKDEVRAVVDEYRAAGVRRIVALRGDPAAGIGTVYTPHP
EGFVQTADLVRALAEYGDFDISVSAYPEKHPESPDMAADIDVLKRKADAGATRALTQFFF
DNDTFFRYMDEVAAAGITLPVIPGIMPIQNLTQLKRFARRCGAVMPGFLDDRFEGLDEKP
EERAKVAADVAAEQIEGLTERGFNHIHLYTMNRAPLVSAVLDRIGYKPEDARAVAAA
>A0A423I0H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas brassicacearum|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKANAGADSAITQYFFNADSYFY
FVERVRAAGVTIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1Q5KNJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB01883|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSSQWDTDVQHFVD
KCRAGADYAITQMFFRPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPKLSNASF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A1B6YQ46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium EhC02|TrEMBL
MTTPSVSFEFFPPQNLEASFRLWDTVQVLAPLGPRFVSVTYGAGGTTRDLTRDAVATLHK
ASGLNVAAHLTCVNASREETLAIADSFAAAGVSEIVALRGDPPKGSAGFEAHPDGFASSV
ELIAALAETGKFTIRVGAYPEAHPEAANTAADVDWLKRKLDAGATEALTQFFFEAETFFR
FRDACAKAGITAPITPGILPIENWTGARKFALRCGTSVPAWLDDAFDKAIRDGRQDLLAT
ALCTEMCSELIEGGVENLHFYTLNRPELTRDVCHALGVTPKVQLENVA
>A0A1B8F505|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. 05NY08|TrEMBL
MADSPTTDKITDKIAALPQDASYFSLEFFPPKTAMGSTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSKALVDDALKAAKEAGIQNILALRGD
EPRGEYKDALEEGKEGEDEFVWAIDLVKYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
KHDLPYLVDKVQAGADFIMTQLFYDVDAYDNFERVLRDHSSGAFKTVPIIPGLMPIQSYQ
ILRRTTKLSNAKLPDSIIDRLDAVRTDDEMVKKVGVDILAEIVESVKATKQRTKGPKGFH
FYTLNLEKAVAFILERVNLIPSFTPVLTSDVFAVDDITDTIPLPQLLINGEKKNRRQSSV
GSGPHNFVIIDREEASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRPDITSIFVQYLNGTLSALPWSDE
PIAAEANLIKDELVKLNQKGWWTIASQPAVNGARSQDEVVGWGPKGGWVFQKAFVELFVP
TSDWARLKPLLEGNGEVSFLAQSASGEFLKSKLDLGPGEEGTETNAVTWGVFPGKEIVSP
TIVEEVSFRAWAEEAWQMWGEWAAVFGKSGEESRRFLDGVAKDGWLVNVIWHDFVGMCKA
KEGRSEEEGYKGLWDVLIAA
>A0A1G8LCG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter subterraneus|TrEMBL
MGLPARVEIVPGGDIVAQVRRHLAPGATVTITCLPHHGPEETVQLAGELAALGYRAVPHL
AARTIASRHQLAEFTARLGDAGMRDLFVIAGDSREAAGPYAWSLPLMEDLAEIGGFEAGF
AAYPEGHPTIAEPELTELLLKKQELGSWAVTQMCFSGDVLTDYVGRLRADGVTVPVWAGV
PGRVRRTRLIALAGRIGVGPSLKFAQRSGSLLRTVLAPSSYDPSPLVRSVEKAGGFAGLH
VYSFNDFG
>A0A7Z0HV12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc sp. DB-1|TrEMBL
MTRITDIYKKKSAPVLSFEIFPPKTEDGLHALYKTLQEVNPKETGVDYISVTYGAGGGSN
HKRTKEIAEYIERNCGITALHNLTGINQTPSSLKGNLEKISVAGVENIFALRGDTPTKDY
VNEYYPFAKDLIKEIKKDGRFDIGAAIYPEGHVDNPTTGISVTGVKEKVISGTEFLISQL
FFDNGVFYNMQEALKENYIKVPVSAGILPIISRAQVERITYMIGSSLPARLAKIVHKYED
QPEALQQAGIEYALEQIHDLLDHGVDGIHLYAMNQPNVLKIMLPEINRHIQSKILTL
>A0A6G0UN25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halicephalobus sp. NKZ332|TrEMBL
MGGDPTGHADSTLHKKGYEFIQRKKKQSLRIAFIVKKVERKMEKEVGIWKELNSAVFLNT
IWATFCVKMAAVQPLQINGHNDYGNGSLLELKKNMSATRLHSPQPYSGDGSENSNGLKFC
HIDSKNDLRETTNYVPLHKRIESKIESGTPFFSLEFFPPKTANGVTNFLTRIDRYRDGGP
MFLDITWHLGSDPANTNKETSSSSIAAACLEYGRVDTMLHMTCAQYTKEQTMDHLKLAEN
IGMRNILALRGDLPQSDSAPIVYPYRALDMIKWIRNEFGNYFTIACSGYPLGHPEAPSYQ
ADINYLKMKVDAGADFVVTQLFFEAETFETFVKDCRAAGINVPIIPGVMPIQSFDSIKRV
ADLSKLTIPENILKTLEPIKHDDEAVRKFGIQHAVDMCRRLLDNKTAPSIHLYTMNREGS
CREILQTLGLWQKESIRYLPWLPHGGHHPVRCREDVRPIYWCARPKSYIFRTKDWDEYPN
GRWGNSSSPAFNNLQEYYMFYLKGLPKKEELLKMYSPELKSIDQVSNVFVRFLTQEPDEE
GIKVTRLPWSEQESDTSTETQLIKQQLIWCNANNIFTINSQPSVNGAPSTDPIVGWGNSG
GYCYQKAYLEFFIDSKRAIKLKEILNEHPFVNYHIINQKGTIDWSNIEPTTPIAVTWGVF
PGREIQQPTVVDPLSFRVWKDEAYDAWLNGWANIYPQNSPSYNLIKSIHDEFCLVTLVDN
DFVKPSVIFELLEQTIAE
>M9LZ85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida antarctica|TrEMBL
MAASSSSSAPGAHAAAAPHPVHITAKIQQANARDAPFWSFEFFPPKTTQGLANLYSRIAR
MRANLDPSWIHVTWGAGGTTVEKSLELAGRIQKGRLDPATPLLSADGRDSEASQQGQHEG
ADACDVCLHLTCTNVQKASLDQTLLAAKRLGIRNILALRGDPPRGEEYWVAADERFQHAT
DLVRYIRESHGDHFCIGVAGYPEGHADYVDRDVQRDLAFLKQKQDAGAQYIVTQLFYDVD
RFLAWYKDARAMGITIPILPGIMPIQNYQSFRRMTNLCKVQIPPLVLEALEPIKADDAAV
KEYGVALGIHMIGRIFLESDIRGFHLCSLNLEKSIERILDGLGWKTDVGALAEADVRLSA
VPAHLHLERTNNQMLSDRTGANTPRDFKVTTQEALKRTLARTSSSYQVPETTTWDEFPNG
RYGDSRSPAFGEMDGYGVSLKVPAADALRIWGHPVTLADISTIFASYLEEKIACIPWCDA
PLMHETLQIRDHLLALNRLGATPDAGKGWWSVGSQPAIDGAPSTDPVVGFGPSGGFIFQK
AFVELFVSASDKDALVEAIDVMGPHAQYTYFAGNARGDFVSNLAEGEANTVTWAVFPGKE
IVQSTIIERDSFEAWREEAFGIWNEWAMLFPKASASRQLIDGVTNDRWLVTIIHHDYKDA
QALWKFLAQ
>M9LZ85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudozyma antarctica (strain T-34)|TrEMBL
MAASSSSSAPGAHAAAAPHPVHITAKIQQANARDAPFWSFEFFPPKTTQGLANLYSRIAR
MRANLDPSWIHVTWGAGGTTVEKSLELAGRIQKGRLDPATPLLSADGRDSEASQQGQHEG
ADACDVCLHLTCTNVQKASLDQTLLAAKRLGIRNILALRGDPPRGEEYWVAADERFQHAT
DLVRYIRESHGDHFCIGVAGYPEGHADYVDRDVQRDLAFLKQKQDAGAQYIVTQLFYDVD
RFLAWYKDARAMGITIPILPGIMPIQNYQSFRRMTNLCKVQIPPLVLEALEPIKADDAAV
KEYGVALGIHMIGRIFLESDIRGFHLCSLNLEKSIERILDGLGWKTDVGALAEADVRLSA
VPAHLHLERTNNQMLSDRTGANTPRDFKVTTQEALKRTLARTSSSYQVPETTTWDEFPNG
RYGDSRSPAFGEMDGYGVSLKVPAADALRIWGHPVTLADISTIFASYLEEKIACIPWCDA
PLMHETLQIRDHLLALNRLGATPDAGKGWWSVGSQPAIDGAPSTDPVVGFGPSGGFIFQK
AFVELFVSASDKDALVEAIDVMGPHAQYTYFAGNARGDFVSNLAEGEANTVTWAVFPGKE
IVQSTIIERDSFEAWREEAFGIWNEWAMLFPKASASRQLIDGVTNDRWLVTIIHHDYKDA
QALWKFLAQ
>A0A290ZTJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera sp. K11|TrEMBL
MNTEISIEFFPPQTAEGADKLRTTCEKLAALKPAFFSVTYGAGGSTRERTFAAVKEIAAA
GHEAAPHLSCIGSTRDSIRSILQEYADAGIRRIVALRGDLPSGVVDPGEFRYASELVEFI
RAETGDRFHIEIAAYPEWHPQARSPRDDLLAFKRKAEAGADSAITQYFYNLDAYLHFVDA
VRGMGVTIPVVPGIMPVGSFSKLARFSDACGAEIPRWMRKTFESYGDDAESIRAFGLDVV
TRLCEKLIAAGAPGLHFYSMNMAGPTTEICRRLGLDGPPRP
>A0A087D2K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium ruminantium|TrEMBL
MHSPMFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSFDRTLTARIAHTVG
EYGIPCVAHLTAQYLDKDDVDEALDLFDQAGVSGVLALRGDRVEGAEPAGVFDHASDLAD
YIRQKRPNLKIYGACYPEKHPQAATLDEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCQSRVPEKLSVLLDKWGGDTALLKEAGITY
ASEQICDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A2I1PNP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDHEDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIHSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKISEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A435XUX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7D.F.Ca.US.004.03.1.1|TrEMBL
RTARTVKRILTETAIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGEP
YRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRAI
TQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFRQVANFSARAGAHVPGWLAERFEG
LDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHDAEAAG
SAAA
>A0A4R4XHC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. KC06|TrEMBL
MPRLRPDRPPAVRELLASGAKSFSFEFFPPKTDKGARNLWRTIRELEPLHPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVNHSQAELRQLIGRFASVGVRNILAVRGDPP
GDPMGEWVKHPDGVEYAADLVRMIRSYGDFSVGVAAFPYKHPRSPDVESDTRHFVEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDVPILPGIMPVTQISTIERSEQLSGAPFPPEV
KARFDAVADDPDAVRRLGIEHAAGLCQELLDQDAPGIHFITFNKSTATREVYGLLDAGGY
GASGRVPPMTA
>A0A368AUQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. AFG_SD02_1510_Pfu_092|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKADLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VAFIREETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>G0JN37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus ferrivorans SS3|TrEMBL
MAHSVEFFPPKNAAGEERLREAISALLPLGPEYASVTFGAGGSTRERTFVTVAMIRQDYD
LEAVPHLSCIGSTEAGIREILEDYQKQGIRRIVALRGDLPEGMENPGHFQHAADLVAFIR
HFGGFDVYVAGYPEIHPRATSARDDVAHLVTKVQAGADAIITQYFFNPDAYLQLRDDLQR
QGVDVPVVVGVMPITNFEQISRFSAMCGADIPQYVRRRMEAYADDPQSQYQLGIELLSRQ
CQLLLREGAPSLHFYTLNQAEATVAIWRNLSL
>A0A086AX16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. JM1|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIEN
IMALRGDAMKGHQYFEPTPGGHASAMDLVHQINDLGRGKYLHNDEEACDELNKFCVGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVTKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEELINEVEKAKNNEAVKQIGVEWAINQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A4Q4GYT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter piscicola|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKQRIAELLDLYKSQGIERIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDLDIQRFCDKARAGANAALTQFFFNPDAYFYFV
DRIQKEGVDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A1Y3YNL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoflavonifractor sp. An44|TrEMBL
MKIAELFGQGRPVFSCEIFPPKRDSPIDSIYRTLDGLKDIRPDFISVTYGAGGGGNVNHS
TQEIACMIENEYHITAMAHLTCVGCTKESALEVMNTLKAGGVENILALRGDHNPNAVSHT
DFLHADDLVSWIRQHGDFGISGACYPEGHPESPDVVSDIRYLKQKVDAGVTHLVSQLFFD
NDDFLRFWERCRLAGIEVPIEAGIMPVLSKASIQRMVSMCGASLPRKLTRILARYGDHPQ
AMREAGIAYAIDQISDLIAAGVDGIHLYTMNNPQVARQISDSITAIRSV
>A0A432TTY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thioglobus sp|TrEMBL
MKTSFEFFPPRTDKGKQSLAQVRQELSKIHPEYFSVTFGAGGTTQDATLETVLDIQANDG
ISAAPHLSCIDSKKSKIIELLDQYKAADINRLVALRGDIPSGVRDIGDFHYANELVEFIK
SEYNDHFHIEVAAYPEVHPQAKNIQTDLQHFANKVKAGADAAITQYFYNADAYFRFKDEV
EKMGVDIPITPGIMPITNYTQLLRFSNMCGAEIPKWILERLKLYENDLESLTLFGTEVVS
NLCRTLKDQGVDSFHFYSMNRTEPSLAIAKSLI
>A0A1I3PYS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium canum|TrEMBL
MALGRPSILPDRVPTVRELLAAGGRSFSFEFFPPKTDEGERQLWRAIRELEALRPAFVSV
TYGAGGGTRDRTVGLVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPPGDPAGEWVRHPEGVLYADELVRLIRQAGDFCVGVAAFPYKHPRSGSVEADTEHFVR
KCRAGADYAITQMFFRADDYLRLRDRVAAKGCDTPIIPGIMPVTQMSTIARSEQLSGAPF
PAEVAARFEAVADDPAAVRRLGVEHAAELCQTLLDEGVPGIHFITFNRSSATREVYQALD
VAPAKAALTV
>A0A3S2AAQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7D.F.Ca.US.004.03.1.1|TrEMBL
MIGRQRDENPAGIDLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIASGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>M4TPL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis Xac29-1|TrEMBL
MPSGASTITDTYSLEVSVKDIGALTNAAPRILPGSDMFIPYLPGQTEAARLAAAQRVRRL
GFEPVPHLSARRIGSLEELQAVIARLVGEADVTRCLVIAGDPSTPKGPFADSVSLIETGV
FERSGIRTIGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDADIVMTW
LEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGNAGPDR
FVDRLVSRLTEAHGDVRLHFFPFGGIAQSVEWVAHYRSCEASQDRVSSVAAD
>A0A2M9GZJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter ruhlandii|TrEMBL
MNSLKQALDEKRFACVLEVIPQQSPARLAALEPIMRRGHLAGWPLLPAFADRVGPHADLS
PLQGAGALGDPASSLLHFSGKDRERADLLRQMAAMGARGLKQLLLLSGDRLPGHDPGRAP
VRYLESVPALQIAREHGPDWLLGAALNPFKYREEEGGAQYLKARKKLLAGADFLTLQLGF
DAAKHIEAQAWMRAQPGAKPMLACVMNLSERRADVLQAVPGIVITESMRQLLGKEREVSH
AYASARSLARLALQIVGLQWMGYAGVHLSGVHTLDELLLLEQAIIEQRGKVTSLADWSER
WQAGWRLPGAPEVRFTPGIDAWTLGQADVVATRRERLRYALLATVHEQFFDRAGWFSRAF
GWSVTRPMWQAGVAANALRAVERTIKRPLVGCDTCGSCRLQDTLYVCPETCPKGLANGPC
GGTRLNRCEFGDRECVHSVKYRIAKSTNQLPALAQTLIPGVEAQDRHRSSWPEWFKQEDS
APGS
>A0A8H7Q3D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Umbelopsis vinacea|TrEMBL
MKVIDKIRKAEEEGRVYWSFEYFPPKTQQGVVNLYDRMERMYRLGPEFIDVTWGAGGLSA
DLTSEIVSTAQSVYGLETMMHLTCTNMPKEKIDTALKLAKECGCQNILALRGDPPRGKDT
WESCEGGFQYAEDLVKYIREQYGDYFGIAVAVGFAGHPEGHVDNPSKEDDLQHLKSKVDA
GADIIVTQLFFDIEMFLDFIKRCRAIGITCPILPGILPIQNYNGLKRVISFNNNYVPEHI
WKDLELIKDDDAAVKDYGIDLAVTFIKRMLEEGIRGFHIYTFNLERSTRLILERLGYTAP
SENVKPLPWNPSLHAKRTKENVRPIFWKNRTKSYIQRTESWDEFPNGRWGDSRSPAFGEL
DGYGVSLKYPTPECLKMWGNPTCLDDIAMLFARYCKGKLDALPWCAQQLDRETDIIRQRL
SAINLLGYLTINSQPAVNGVKSSDLTYGWGPKNGYVFQKAYLEFFVAPEQLDDLIAKIST
NPEITYFAVNSNGDLRTNTQSDTPNAVTWGVFPGKEILQPTIVESTAFMAWKDEAFELWQ
EWARIYEANSESAKLLTDIHDNWYLINIVNNDFQDDAGIWRYFDLEIDGEISRRLRRSSA
DAAN
>A0A0G4FJW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromera velia CCMP2878|TrEMBL
MRVDQKIREWQEQNPGRYFFSFEYFPPKTETGTLNLYDRLDRMGMLNPMWIDITWGAGGS
TADKTMDICLNAVRYHGLEPMMHLTCTNMKKEMIDEALEKCKENGIQNVLALRGDPPHNQ
ERWTAVEGGFQYASDLVAYIREKHGEYFCIAVAGYPEGHLENESRDDDLKNLKYKVDMGA
NFIVTQLFYDNDEFMAFVKRARDIGIECPIIPGIMPIQNYAGFKRMTTLCKTKVPPAVLE
DLETIKDDDGAVKDFGVKLCIQMCKRLMKEGVCPGLHFYTLNLEVSVMRIVDGLELVADH
VSSRALPWKRSVHPSRDKEEVRPIFWANRPKSYIKRTMEWDDFPNGRWGKIDSPAYGDGF
VSASQNPDETSMSHRRKMWGEDLASFDDVFRVFTCFIKNDPTVPRIPWCPDAPAEETNFL
KKQLVAMNKKGLLTINSQPRVNGALSSDPYFGWGPHKGFVYQKAYAEFFCSPGMLTRLIS
AAEAGRLGTNVTYTAVNRQGKVQTNCAEDSVNAVTWGVFPNSEIKQPTVVDYASFVIWKD
EAFSLWVDEWGCLYPDDSKSRQIIEEIANNWWLVNIVDNDFVSGDLFNHLTEEVSDPIKH
KCSFNW
>A0A7G8H5N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. A15-62|TrEMBL
MLTAEVMPPRGADPSHMLAMAASLQGRVHAVNVTDGSRAVMRMSSLASCKLLLEAGLEPV
LQMACRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAGDQSDARPVNEFESVKLLQQVD
ALNRGMDPVQGTLPDGATTLFAGCAADPQSRSWSGLQRRLQRKQAAGARFVQTQMVMDPE
ALERFQRELAGPLDLPVLAGVFLLKSAKNARFINRVVPGACIPDALIHRLECAEHPAMEG
VAIAAEQVKRYLGIVRGVHLMAIKAEERIPMILDRAGLSSLPG
>A8EH20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei 406e|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A1N6IVH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epilithonimonas zeae|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFKPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEPSVGGHKYASDLVKQIHDLGIGEYLHGKIESDVDNSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKFFEFVKQAREIGIDVPIIPGIK
PIATKTHLQMLPQVFKIDLPEALINEVLKCKTNNDVREVGIEWAINQSKELLDFGIPVLH
FYSMGKSDNILKIGREIF
>F3UQ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis SK355|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDTAPKDDFTYAT
DLIEYIKTEAPHFNIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHHPSVQSF
>A0A4S0WF72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2E.F.Ca.ET.166.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDAVIREFVDFGVTRFVALRGDPAAGVGT
VYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
AGSAAA
>A0A2S0XKF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter sp. MSH1|TrEMBL
MNPPRPRQPDEHPDGIDLPLDRLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RARIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPYDFRPVHLGKKIAAGAQFVQSQYCFDVPMFRTFMQQVRDRGYDEKCF
ILVGVGPLASAKTAKWIRSNVPGIHIPDSIIARLEGAQDQKKEGKQICIDIINEVKEIAG
VSGIHVMAYRQEEYVAEIVDESGVLKGRRPWKREARADDQLVADRLEHLLHDDVTESQVD
MVKTAH
>B7JZ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rippkaea orientalis (strain PCC 8801)|TrEMBL
MINRFRQAVQNKEFLITAEVTPPKGGNPTRMLEVAKQLKGRVHGVNVTDGSRAVLRMSSM
AASALLLQYGIEPICQMACRDRNAIGLQADLMGAHALGLRNILALTGDPLKAGDHPQSKS
VFELESVRLLKVIDNLNRGVDFHNKSLPDEALDLFAGAAVDPQSPSWSGLKSRFERKLAA
GAQFFQSQLITDFDRLDKFMHQIAAGTDKPILAGIFLLKSAKNAQFINKNVPGVEIPESI
IKRLADASEPLQEGVKIAAEQVQLAKELCHGVHVMAVKREDLIPQILDLAGVNPIV
>A0A2N2KAM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-15|TrEMBL
MKTQSALERVLEAGLPAVTSECGPPRGAVPEKVKEKAEKLRGYVDAINVTDNQTAMVRMS
SFAACLIIKQMGLHPILQMVTRDRNRLAMQSDIIGAYSHGIDTMLCLSGDHPSFGDHPMA
ANVYDLDSIQFVQMVRKMRDEGKFQGGDDILNAPRMYIGAAANPFADPFELRVARLAKKA
RAGADFVQTQCIYNLERFGKWMEGIRERGLHEKIHILAGVTPMKSAGMAKYMKNKVPGMD
VPDGLIKRMSGIPKEKQAEEGIKICVETIQELKEMKGVAGFHIMAIEWEDRVPEIVERAG
LYPRPL
>D0ZHC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edwardsiella tarda (strain EIB202)|TrEMBL
MSFFHASQHDALNQSLAELQGRIQVSFEFFPPRSQEMEQTLWRSIDRLSTLRPSFISVTY
GANSGERDRTHGVIKGIKERTGLEAAPHLTCVDVSREALRGIARDYWNSGIRHIVALRGD
LPAEGGRPEMYASDLVALLREEADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGASRA
ITQFFFDVESYLRFRDRCAAAGIDAEIVPGILPVSNFRQLQRFAALTNVRVPQWMLAMFD
GLDADAETRKLVGANIAMDMVKLLSREGVKDFHFYTLNRAELSYAICHTLGVRPQGSVA
>A0A843YKK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tritonibacter litoralis|TrEMBL
MSAPEISFEFFPPKSLEASFRLWDTVQVLAPMSPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLNVAAHLTCVNASRAETLEIADQFAQAGVKEIVALRGDPPKGEGQFKPHADGFANSV
ELIEALAATGKFTVRVGAYPDPHPEAPNAQADVDWLKRKIDAGADEALTQFFFEAETFFR
FRDACQKAGIDGDKITPGILPIENWKGARNFAQRCGTVIPAWVDDAFEKAVRDDREDLLA
TSICTELCSELLDGGVKRLHFYTLNRPELTRDVCHALGVQPKVSLENVA
>A0A8E2KIB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC068F04|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHGATHSLFKHHSQVSAL
>A0A3A0SBA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus nepalensis|TrEMBL
MSQLINKLKQNILVADGAMGTILYSDGLDTCPEAYNLTHPEKIERIHRSYIESGADIIQT
NTYGANFEKLKLFGLEHKVKDIHKAAVQIAKKAANNETFILGTVGGFRGVKQEPLSLEAI
QYHTEIQVDTLVEEGIDGLLFETYYDLEELTNIIKATKQKHNIPIVAQLTALNTNYLRDG
TEINTALQQVVNSGADIVGLNCHHGPHHMQQSFSHIELPEHAYLSCYPNASLLDIENSQF
KYSDNAEYFGKVAKQLINEGVRIIGGCCGTTPEHIQFIKSSIANLEPVTHKNVIPIKKYN
SCSRTQTKQQNLTTKVKQRPTIIVELDTPKHLDTELFFRNIKKLDDAHIDAVTLADNSLA
TVRISNVAAASIIKQQYTIEPLVHITCRDRNLIGLQSHLLGLSLLNVNEVLTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNKGINTDGDALKTKTNFNIAGAFDPNVRKLEGSVKR
AEKKIESGTHYFITQPVYSTEKIKEIYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEAILEQFEAVKDDKEKTKALSLKLSKELIDTVHKYFNGLYLITPFQKVDYSLELASY
SQSITSSKQEAIL
>K9BE40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WC-323|TrEMBL
MSLFSQCLEQKQFCILVEYLCSNRDTPAVPSSLAGYPAMMTLADRVHSDEDPAPLELAQK
YAPEVEKLLHFSGKGRDIQEFEHFLDQAEQRGYHNLLLLSGDKLKNHNFGREIPAQRTRY
LESVNAVMAAKQRHLFNIGVAFNPFKYTEAERDAQYLKLHKKIKAGADFLITQLGFDLDC
LQHSQSFISQHYKQFPLIACVMPLSLKRAQFMLKHQVAGLVIPAHIVHVLKSEYEADPVQ
AEANVYARCALQILICKHLGFVGVHLSACHKPQEQQKLEQFLKQYESWSLAACEKAWKDL
WKMDSGLELKPELATFSKPVPPAQIFKYKQMHLMHQLFFASHAALGIGRFIFKANFWNKA
RPDQLLLKMEHWSKHPLVGCESCGHCRLDDTLYICPETCPKGLANGPCGGTSLDRCEFGD
RECIHSVKARLAKRLDQTEVLRSKLIPAISIETRYTSSWKNWFKHSESH
>Q59GJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Homo sapiens|TrEMBL
TCHSGVLMCRGCGCLPPDAPCPTLCSRNPAMVNEARGNSSLNPCLEGSASSGSESSKDSS
RCSTPGLDPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLY
IDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRLEEITGHLHKAKQLGL
KNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDICVAGYPKGHPEAGSFEAD
LKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPIQGYHSLRQLVK
LSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATT
EVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWG
NSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEASVFEVFVLYLSGEPNRNGHKV
TCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQK
AYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREII
QPTVVDPVSFMFWKAHPECERNGGSMTLRPDALRWSHSCPAFLLHSAASLGNSTLLRVSP
TPASTPPPDNGS
>A0A7I9VJR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeromyxobacter sp. Red267|TrEMBL
MKVTDILRFARERGEPVFSFEFFPPRTEDGVRQLFEAVEALRPLAPGFVSVTYGAGGSTR
ARTLELVTRLKRESEVETVAHVTCAGASRQELAQVLDELAAAGVQNVLALRGDPPRGQRV
FEPHPEGFRYASELVAFIRAEPARWSFCVGAAAYPEGHVETRDLARDLAHLKLKVDAGAD
FLVTQLFFHNAHYFRFVERARAAGIALPVLPGIMPFTAVEQVERFTALCGAEIPPRLRAA
MQVRREDAEGSLQLGVAYAGLQCADLLRRGAPGIHFYTLNRSPSTRAIVAALRASEPWRE
G
>A0A3R9WSY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC06614|TrEMBL
MALGTASTRPDRARTVRDILASGKPSYSFEFYAPRTEKGERSLWNALRRVEAVGPSFVSV
TYGAGGSTRGGTVKATQEIAADTILTPVAHLTAVDHSVAELRHVLGQYADAGIRNMLALR
GDPPGDPMGEWVKHPEGVTYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFHPENYLRLRDSVAKAGCDTPIIPEVMAVVNARTLDRLPQLSNAAF
PEDVKERILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITNNSTATLEIYENLGL
HQRA
>A0A1G7HZ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Celeribacter baekdonensis|TrEMBL
MTQAPNISFEFFPPKNIEACFSLFETVQALENMKPGFVSVTYGAGGTTRELTHDAVALLN
RKYGWNVAAHLTCVNATREETLEIANSYKSVGVNEIVALRGDPPKGAGQFTPAPGGFANS
VELIEALAATGNFKIRVGAYPDPHPDAADDSADIVWLKEKFKAGADSAITQFFFDADTFF
RFRDRCAKEGITGKIIPGILPITSWTGVQKFAAACGTPLPAQYANAFETAEDQQAVSIEL
CTKLCETLIQGGVEDLHFYTLNRPTLTKAVCANLGVNA
>A0A0C3LDL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tulasnella calospora MUT 4182|TrEMBL
MVKITQKIAQAERDNRVWWSFEYFPPRTAQGLQNLYDRIERMRMLGPEFIDITWNAGGRT
SDLTCELVKTCQGLVGLETCMHLTCTNMPKEKIDNALRDAKMSGCRNILALRGDPPAGQD
EWSAVEGGFIHGIDLIRHIRANYDDYFEIAIAGFPQHIDLPPAELADEMRWLKDKVDAGA
TLIFTQMFYDVEIFLRWVAAVREAGITVPIVPGIAPIQTWNGFIRSTKLSQTTIPQAYID
VLEPHKNNDEKVREIGIKLVAEMCRKILASPYNIRGLHFYTMNLEKGTKMILEELNLVPR
VEAIKPLPWRQSLTPSRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGEI
DGYGISLKHTKEKALELWGQPTSVEEIRSLFSRFCQGTLKALPWSDEPTALETSIITKHL
ARVNELGFLTINSQPAVNGARSDDRAFGWGPANGFVYQKAYLEFFASPETLNKLLPVISR
DPLITYYAINKQGDLRTNNQSEGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELGV
QWSQIYDHDSPSSKVIKDMMETYFLVNVVHNDFKDPNAIFNGFYEAANASPVTVNGHDVI
ANAKASLVNGMIANGIGENLKNGMQVINDVAHGRGREVEVQ
>A0A424IVE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium TMED227|TrEMBL
MNNIYPKNVNFSYEVFPPQDISNNSKLVEKINALTYKPSFISVTYGAGGSNRDKTMDLVR
RIHQDTDIDVAAHLTCVDSSIRDTMSLVEYYLKIGVNKILALRGDSTNNISKQYEAHPRG
FQKTGELIKAIKKLSDIQVYTAGYPEKHPDSADLKCDIENLKDKINSGSNDIITQYFFDN
NLFYSFRELLTVNKIGANLIPGIIPITNFQKIREFSIKCGASIPKTFEVIFDDHFSNXNN
EEQLEIXLSIIADQAKDLIQNGINNLHIYSLNQISLMDQIINKLNIDNVK
>F3MXX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus rhamnosus MTCC 5462|TrEMBL
MLNKCVRNLLMKISQCFKDHQVISFEVFPPRKNATNIAMRPILNTLDAVKAADPDFVSVT
FGASGNKPHMGTLEVAKLIKMNSTLNPSPIFLLPNSPAPKSMLSCVGFRKPALTTSWLYA
ATSPSPDASVKTSLMPAI
>A0A0K2ZK42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas translucens pv. phlei|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKTYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQASDALSDLRHFKAKVEAGADGAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQALGDDGDAIREFGADLV
AALCQRLLAGGAPALHFYTLNLAKPTTSVLSRLE
>A0A1G3UH67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp. RIFOXYD2_FULL_34_21|TrEMBL
MFDELINKLKNHTYITLETTPAHSPVFSPIVDKIAELGLDKLIDGFTTTDNPLAKLKYNS
LFGAKLLQDRFNKPVIATMSMRDRNKIALQSDLLGANEVDVRAILALTGDPATISDQPHT
KGVFEADSSMLLDIISCFNSGIDYAGKPLSHQPKEIYPFAVVNSYAKNPKSLQKKMQKKI
KHGALGIITQPVYDVENAKQLLELKEAANKECSSENRGAELILGIFPITKLRTAQFLSAH
VPGINVPDYWIEELRIAHEKGANEEYKVGFELSKKLFDNLKAFHPKIHLMTANQFQIAKD
ILV
>A0A358IGA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MKSLLQDNRVHVFDGAMGTLLYSRGVFVNVCYDELNLSRPELVRGIHEEYINAGAEILET
NTFGANPVKLSSFGLEDRTEEINEQAARLAVEASSKAEVSELTKANVPEYFSGGTVAVAG
ALGPLGIRIEPWGPTSLDEAEAYFARQVDGLLEGGVDGFVLETFSDISELQCALRAIRVA
CELPVIAQMTVGPDGKTSFGTEPAHLAQAMEDSGADVIGLNCSVGPAVMLDALEDMAEVT
QLPLSAQPNAGLPRKVRDRKIYLASPEYMAQYARRMIDVGVRFVGGCCGTTPDHTRRMRD
SVAALQPKHPVVTIRDRANSSHSVINSVPLEGRSAWGRKLARGEQIASVEIIPPHSWDAS
AVTSPARELKVSGVDAVSIVESPRSRSRMGALSAALIVEREVGIETIVHYTCRDKNMLGM
ISDLLGAAAAGIRNVLVVSGDPPVMGPYPDTTVVFDIDSIGLTNVVQGLNQGIDPGGNTI
GAPTEFVQGVAINHGAVDQERERSRFKYKIEAGANFAITQPVFSPEALEQFLDATTPEIP
IVAGIWPLTTLRNVEFLANEVPGVHVPTELVDRMKRAQLSGADAALEEGIAIALEMINAT
QGFVQGFQLTAPNRKVQVALKVLRESGILATA
>C2VYW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus Rock3-42|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGTNVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATGFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7V8JEE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. LD120|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAGYNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVRIPAAPHLSCVGDSKDDLRGLLKQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLFNFVRKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EHVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWKNLKLPR
>A0A523NDU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTSTGIPETPTVRPGERPFGEFLAGSGIALFDGAMGTMLYAKGIFINLAFEELNLSRPGL
VREVHAEYVAAGADILESNTFAANRFRLSPHGLADSVAAINISGVEIAREAAGGHAWVAG
AMGPLGVRIEPFGPISRNEAREVFEEQARALAEAGVDLFIIETFSHLPEMEEAIRAVRAV
ADVPIVAQVAVAKRGVTREGVAPGQAAVLLAEAGADAVGVNCSEALSVLDALEGMHEAVA
TPLSAQPNAGQPHTVDGRNIYLATPDYLVAWGRRAIRGGARLLGGCCGTTPDHIRALRQA
IGGGAAPVAAAPRIIKPVVSARTPTPLPPDTKSRLAKALLHGQFVTGVELPLPTGWEVDR
INAATQRLDDAGLTFVAFPDGPRNEARMSPITMAQLVTRPQGVEPVVHYSCRARRLPRIQ
SDMLGACAQGIANILVVTGEPISPGMDAPADLDVDSIGAVNLLVCLNHGQDLGGNVIGRP
TRFFTGVRIDPTHFDRERELSRLFWKVDAGAEFAITAPVFDPHALQEFLAGWNGPTIPLI
ATIWPLRSAREAEFFEQELAEVPVPAELVKRMQQAEKDGREIEEGIAIARELAVAIKPQV
QGIQIVAPDLKVESALAVLG
>A0A2E4BZZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MDGAMGTELYASGVFVNVSYDGLNLETPDVVETVHRNYVNAGAEVIETNTFGANPVKLSS
YGLADRTEEINHAAVGLARRSAQGRALVVGAIGPLGIRIEPLGPTSREEAQEFYKRQVDG
LVEGRVDGFVLETFSDLNEMEQAFKAVRSRSPLPVICQVTVGDDACTSYGTSPEDVATEV
ASWGASVIGLNCSVGPAVMLEAVERMAEVTDLPLSAQPNAGLPRAVGDRKIYLASPKYMA
QYARRMIEAGARFVGGCCGTSPEHIRSIRALVGGVRPPSTRARPGSHAESHDTPIQPEVP
LGERSVWGRQIAEGTFVTSVEVTPPKGWNAEILLGQCRRIQAAEANTVNVLDHPHAHTRM
SALPAAMLIEREVEIETIVHYPCRDRNMTRMISDLLGAAAAGLHNLLLVTGRPPAMGPYP
DSTASLDIDSIGLTNVVHGLNRGVDPGGNAIGVPTRFVIGVRVSQVAVDQDREAGRLNWK
VDAGADFVITRPVFDAEQLHSFLERVPELSVPIIASLRPLTSLREAEFLHNEIPGIQIPD
RVLARIATAEAHGEDAARAEGVSIAMEAFAAVRDSIAGVHIHVADGNLDGALELLSEIRD
SA
>A0A2V7JVC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTITLRDLLNDGKVHVLDGAMGTMLYSKGFFLNVCYDELNLKQPKLVQEVHAAYVRAGAE
ILETNTFGANPVKLGSFGLADDTDKINQAAAELARAASGGQTSVVGAIGPLGVRIEPFGA
LAREEAFAHFQRQVTGLVAGGRGVDGFILETFSDVDELHEALRAVRSLSDLPVIAQMTIG
DDGLTHYGTAPETFAQQLAEWGADVIGVNCSVGPAGVLEAVEKMVKVTDRPISAVPNAGL
PKDVGDRKIYLASPEYMASYARRMIEAGARIVGGCCGTTPEHIKKIRDYVASVVPRHQPV
VVSREAVAPPAGVAAVPLARRSCFGAKLAAGQLVTSVEIVPPRGVDPAPMFAQCRALKAA
GVDAVNVPDGPRAQSRMGALLSSIMIQREVGIETVTHYSCRDRNLLGMLSDVLGAAAAGL
RNILIITGDPPKMGPYPDATAVFDIDAIGLTNLVYRLNHGLDPGNNPIGQPTEFAIGVGV
NPAAIDLDRELSRFAWKVDAGADFAVTQPVFDPKQLADFLKRVEQFRIPIVAGIWPLVSL
RNAEFLANEVPGVSVPETVLARMKQAQEKGKEAALAEGVAIAREMFQQVKGAVQGIQVSA
PFGRVEVALEVFGG
>A0A7Z9JRD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MRSLIEDGHIHVFDGAMGSVLYTRGVFVNICFDELSLRKPEIVRRIHEEYVAAGAEILET
NTFGANPVKLSSHGLGDRTEEINEAATHLARDAAAGQAAVVGAIGPLGIRIEPWGPTERA
EATAFFERQVTGLLAGGVDGFILETFSDLSEIDCAFAAVRKLSNLPVIAQMTVGHNSKTA
YGHKASQIAEELTKIGVDVIGLNCSVGPAVMLDAIEDMADATSLPLSAQPNAGLPQTVRD
RKIYMATPKYMALYARRMIDAGVRFVGGCCGTTPDHIKHIRDTVRLVQPRAVTVRVPDVP
QDRLEILDPVPLEACSAWGRKLSQGEPVVSVEVLPPRGWDRNAIVDPARRLKVAGVDTLA
IVDGPHSRSRMGALSAAVIVEQEVEIEAMVHYTCRDRNMLGMISDLLGAAAAGIRNLLVV
SGDPSVQGPYPDMTEVFDIDSIGLTNVVRGLNRGVDPAGNSIGEPTKFVQGVVANPGALD
LEREVTRFRYKVEAGASFVVTQPIFDPETLESFLEQVHAWKIPVLAGIWPFLNLRNAEFL
ANEVPGVTVPEEIVDRMRKAQASGDEEAMDQGVRIAVEMIKAVRPLVQGFHLSAPSRRVD
VALRVLHEAGISPNA
>A0A8C0K5R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Canis lupus dingo|TrEMBL
MDQPPPGVLPATVRCSRLGLWTLEAGRVGFSVPPSISRSPAMVKEPRGDGDGGPTPRSEG
SSSGSESSKDSSRCSTPGLDPERHERLREKMRRRMESGDRWFSLEFFPPRTAEGAVNLIS
RFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQI
TGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYP
KGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFP
IQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGL
HFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRT
QEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARY
LSGEPNQHGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIV
GWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNA
VTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFL
VNLVDNEFPLDNCLWQVVEDTFELLKGPSPEREAEAV
>A0A8E2HGR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea sp. 64-18|TrEMBL
MTQPSFSFEFFPPKTAEGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQGTLDTVVEIQR
EGVEAAPHLSCVGSTKDNIREILQTYRQHGIRHIVALRGDLPSGMGEIGEFRYASELVEF
IRAETGEWFHIEVAAYPEYHPQAKSPRLDLEHFAHKVKAGANAAITQYFFNADAYFRFVD
DASRLGVDVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDRDSIRAFGLDV
VTALCERLLAQGVPGLHFYTLNAASATKAMWQRLGL
>A0A7Y2KWM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GC01|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETADHFHIEVAAYPEMHPQARNFEDDINNFVRKAHAGADSAITQYFFNADSYFR
FVERVRAAGVTIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIQSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2E9MLH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MSSTCTRPLIRIAESLHCHIPSVRASAQRWLTGDHIDRHAGDKHLRKLVTDQVQAGADFL
DVNVDDFFTVEGIGHDGARQVLAHILHLIAEYGHGVPPCIDSSDPSILEYGLQVDREGRG
ARGGRMPLVNSVTINRLEALQLRSGLPFAVVGMLLEKAGDDGATGFTDIADAAIYHETAK
QIFDAARDAGFSAQDVFFDPTVGPLGADMVGYTKRTFEGIRMIREDAGMAGAHVVLGLSN
CSDGLPRRLAINRAYLRVAMEYGVDAAICDVGQISGKDLVDGRVLKLIRKIATGDAEAGA
TDALILLVDYAQSQRRAPAAPSRSTKFDDPFGRALDDPTGEPVFILELAPSEGGLDQIFD
VAEKARDEDYIFTITDTPGGNRTPGPDTLALEVARLSGRQPIMNLSCKSDDRNALIRRAL
ALYHQGLHHFFAVTGDYTNGGRPVFDLDAVSLAMALDSLRRGLEFPDLLPRAGGALDQLR
IGSAVSPFKYDEADSWGQYLKVWKKRRAGADYLITQLGYDVAKFQELKIWMSRAGMSDTP
VFPMVYFLTPQFLRVLNRVHVAGAVIPDELKRKYQGRLGSKQEVKELRALNFSDLASHQH
RQAVRRAALLSHILLDGFRFRGIDLAGITQLDDARAVRDELASLAGCDWHASWEEYRDAD
GTRPMQLSPSEDAFYLFEQREDGLLQEDSPLLRGDRSAYQPIDPQMKRLHGRYFEPGRGL
NGLLQWMVGGAPDGSRLKWATLLEQATKRSKLGCEMCGDCRIADLAYLCPEPTTGCAKRL
LNGPCAGADLQGGCEVTPERRCYWGRVLEATLADGGVEGLLALQPPKDPSLSHTSSWRNE
VEGRCPQSLDLGLPPSEALPPR
>Q9N0Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
VIASTAVNYCGLETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGDPVGDQWEAEEG
GFSYAADLVKHIRSEFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLF
FEADTFFRFLKACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDN
DAA
>A0A352F2Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MEPFRDILETDRIHVFDGAMGTQLYAKGVYINRCYDELNLTNPDLVQEVHSEYVQAGADI
IETNTFGATAHNLNQYGLADNLREININAARIARAAADERAYVAGAIGPLGLRIEPYGPT
SFDEAKDMFKVQVEALLEGGVDLFVLETFSDVSAMRQAIRAVRELSDLPIIAQMTILTDG
NTSYGTTPELFTARLDEWGADVIGLNCGVGPAIILSALEKMRAVTKKKLAAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRFIQAGAKFIGGCCGTTPAHIKLISDAVRAASPRAQKVVMT
SGALAHISEGAPADLKIVPAAERSHWSRKIVNGEFVTSVEVLPPKGVDAVKTLDSIRLLK
DAGVDGVNIPDGARAQSRMSALATAVLVEQQIGIESVLHYCCRDRNLLGMMSDLLGAAAL
GIRNLLLITGDPPKMGPYPDATAVFDIDAIGLTNMVNKLNHGLDIGNNPIGQPTAFCIGV
GVNPGAINLDEEIRRFEYKVEAGAQYAITQPVFDTDQLRDFIKAIEHVRIPIVAGIWPLV
SYRNAEFLHNEVPGVRVTPSIMERMRAASTISKEAGRDEGLKIARESLSEVRDLIQGVQV
SAPFGNVKYALEVFGALEEFAPAKKDEAGFAQKAPNA
>A0A416SQY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF19-22AC|TrEMBL
MKIIDRLKEDRIHISFEVFPPKTDAGVDNVMRATDRIAELRPDFISVTYGAGGGTSRNTA
KIAKHIKEDLGVESLAHLTCASSTKDEVRGVISNLKELGIENILALRGDIPADQPFPTED
RFHYAYELVEEIRRSGDFCIGAACYPEGHVENEHKEDDIKFLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAKQMKRSLELSGTVFPRRFQAILDRFGDYPN
AMEQAGIAYATDQIIDLLANGVKNIHIYSMNKPETAEAIMRNLSEIIKC
>U3IQI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anas platyrhynchos platyrhynchos|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYESDLKHLKEKVLAGADFIITQLFFRSETFIK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYISGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A3QA96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella loihica (strain ATCC BAA-1088 / PV-4)|TrEMBL
MAFHHAQHANSLNQSLSELNGDINVSFEFFPPATPEMETILWNSIRRLEPLKPKFVSVTY
GANSGVRDRTHGVIERIQKETDLVAAPHLTLVDASDEELVELAKHYWNSGIRDIVALRGD
LPAGSPKPTRFANDLVRLLKSVADFDISVAAYPEVHPDAPNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSIPSWLHKQFE
GLDDDPSTRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A352VRJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
VEHEVGIESLVHYTCRDRNMLGMISDLLGAAAAGIRNVLVVSGEPLLQGPYPDVTAVFDI
DSIGMTNVMNGLNRGIDPGGNSIGAPTEFVQGVAANPGAVDQEREVERYRYKVEAGANFA
VTQPIFDPEALERFLERVGSGSIPMIAGIWPFLSLRNAEFLAHEVPGVVVPDAIVERMRG
AQESGPEAALEEGVLIALEMIEAVRPHVQGYHLSAPSRRVDVALRVLREAGVSATA
>A0A0M7H6T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLREILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAASVSADMDHFVAKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHSQLLRFSEMCGAEVPRWIRLRLAELGDDKASIRAF
GVDVITELCQNLLDNGAPGLHFYTLNHAEAPLAVWKELGV
>A0A1W6MSA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystis bryophila|TrEMBL
MSIEPRHPLSPKGEFVISYEFFPPKTPEMETQLWASVKRLEPLHPRFVSVTYGAGGTTRE
RTHAIVLRIARETGMKPAAHLTCVASTREETDRIIRAYWEAGVRHIVALRGDPPGGVGSP
FMPHPLGYPSSSHLVRGIKAIADFEISVSTYPEGHPESRSIDQDIDALKAKIDCGATRAI
TQFFFENEVYLRFLERARARGITIPIVPGIMPVRNFKQVSGFAKKAGASVPAWLADRFEG
LENDQETHAIVAAATVVEQVMDLVKNGVNEFHFYTNNRADLVFGICHLLGVRPVREKVEA
>V6F6G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum gryphiswaldense (strain DSM 6361 / JCM 21280 / NBRC 15271 / MSR-1)|TrEMBL
MNLPIAAASAKPVSVSFEFFPPKTEKMQETLWECVKRLEPLAPSFVSVTYGAGGTTRERT
HDTVVRIARESSLKPAAHLTCVGHSQGEVDDIARRYWDEGIRHIVALRGDAPEGSGAYQP
TPGGYAYAVDLVKGLKRINDFEISVAAYPEMHPDAPNADFDLDNLKRKVDAGATRAITQY
FFDVDVYRRFIDRVRAAGITVPVLPGILPVTNFAQVQKFSAACGASVPAWMAKLFEGLDN
DPETRRLVAATVAAEQCRALAADGVTDFHFYTLNRADLAYAISHILGVRPKAQ
>A0A2E6I0R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MHHRHLRCDGFNAGQDTRNRYAHPERIRCGLRPSPDLRRRLQRRDRTNLIPNRIGRLQEH
RGAAGRPTSGQRKFRRPPDGFEHANQLVAHIQNTEPTDAPFGVAVAGYPEKHLEAESFET
DLLNLKRKVDAGADLVVTQLFYDNDSFFRFKDNATSAGITVPIVPGLMPIQSSGQIQRIT
SMCGASIPDDLQRRLDDTLDAVSI
>A0A0C5JC53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rugosibacter aromaticivorans|TrEMBL
MNLELSIEFFPPQTAEGIEKLRATREQLAILQPAFFSVTYGAGGSTQERTLATVSEIAAA
DHVAAPHLSCIGATRASIRELLATFRVRGIRRIVALRGDLPSGMADPGEFRYANELVAFI
REETGDAFHIDVAAYPEWHPQAKSPRDDLRHFKQKIDAGANAAITQYFYNPDAYTRFVAD
ARALGVTVPITPGIMPIASFSKLARFSDACGAEIPRWMRKQFESFGDDTASVQAFGLEVV
TDLCQQLIARGVPGLHFYSMNQSWLTLEICRRLGIG
>A0A219AC05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. VAUSW3|TrEMBL
MKITDHIKNAKGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERKITRMRPGTLGICAAIQHKYNVDTVPHVLCGGFTMEETEYLLVDCMYLGIEN
VMALRGDAMKGQQYFEPAVGGHRNAVDLVHQINDLGRGKYLHDEKACDENNKFCIGVAGY
PEKHIEAPSMNYDLKWLKEKVDAGADYVVTQMFFDNKKFIDFVKQARDMGINVPIIPGIK
PIATKAHLQMLPKVFKIDLPEELISAVEKAKDNTAVKQIGIEWAIQQCRELIDFGVPVLH
FYSMGKSDNIKKIAGELF
>A0A7G7FU03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metabacillus sp. KUDC1714|TrEMBL
MSFLEDLKSKILIGDGAMGTMLYSHGVDRCFEELNLSKPDDVKRVHQAYIQAGANLIQTN
TYGANDIKLSRYGLEDEIRQINKTAVEIAKRAATSSTYVFGTIGGVRSFKKSAHTLEEIK
RNFREQLFILLNEDVDGLLLETYYDLEEMKTVLQIAKKETNKPIIANVSLHEAGVLQDGT
ALTDAFSTLEELGANVIGLNCRLGPYHMIQSLEEVPLLESAYLSVFPNSSLPALNEGRLV
YESDEGYFKESALKFRDQGVRLIGGCCGTTPKHIQAIAEAVGHLAPVTDKKVRVPKQVQV
NITSSNTDTLPPLQEIVKEKRSVIVELDPPKKLGMNKFLEGAQALHHAGIDALTLADNSL
ASPRVSNLAAGILAKEKTGGRALIHITCRDRNLIGLQSHLMGLHSLGLSDVLAITGDPSK
IGDFPGATSVYDVSSFDLISLIKQFNEGVSYSGKPLGEKTNFSVAAAFNPNVRHLDKAVV
RLEKKIAHGADYFISQPLYSSQQIVDVYEETRNLKAPIYIGIMPLTSSRNAEFIHNEIPG
IKLSDSIREKMAAAGTDKEQARQEGLAIAKDLIDTAFDLFNGIYLITPFLQYDLTVELTN
YIHEKEKQLAERKITHV
>A0A341BS61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neophocaena asiaeorientalis asiaeorientalis|TrEMBL
MDRPKPRVLPAGHCCPSLGMRAWEAGSARFSVPPSIRSSAMVNEPRGHGGPSPRWESSSS
GSESSKDSSRCSTPVLDPERHERLREKMKRRVESGDKWFSLEFFPPRTAEGAVNLISRFD
RMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITGH
LHKAKRLGLKNILALRGDPTGDQWEEEDGGFNYAVDLVKHIRSEFGDYFDVCVAGYPKGH
PDAESFEAGLKHLKEKVAAGADFVITQLFFEADTFFRFVRACSEIGITCPILPGIFPIQG
YRSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQALSLCRELLASGSVPGLHFY
TLNREVATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFAHYLSG
EPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGWG
PGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGDNITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRTIIQHIHDNYFLVNL
VDNEFPLDSCLWQVVEDTFELLSGPPQSKRETEAP
>A0A7C5ZQN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MNDKVIFEVICPPLNWDKEKKQEFIEKICVLLKRNNLNYINLPQIVDENRSGNRIFKFKP
KEENYVFAKELLSYSLNYFQHKIDPIINIVVPRIPKEEFIEFFKMLYEMGYRNFIFVGKD
NSNIEYPGLEVYQASYLIKEKYDDVKIGGIVIFHRENEIKRIINKISHGMDFFVSQIIYD
TQDFENFINIPMDIKTTIYISVAPISSQKEIDFLKWLGVKFNYHPVNNPQQYFENQIKQV
INKIIEENFNCILKGRNLYFGINVEHITYNNIKLSEEIIKLANLRIENLKILSKKLLLKR
GE
>Q9YFU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)|TrEMBL
MEVWVELKPVYGLEMAAKALKYLSFADKIDIPDQPVGVAFSSPIAASYLSCRVGGERIVA
HIRTVDYSVHSLKAIVKTLSSLGVSNIVLLRGDPLGREVGLKPEEAYEIAARYRERFGVK
LGFILSLRRSVQEMFERLRLNPDFVLVLNSSKHYLWKLEKIRQAYAGEVIAYLVIATEKS
VRLMQGKITSAMYTENEVLDLAEKMVSGRLVDGVLVSAPGDDAALERVARRVKRYG
>A0A837NVP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum WJL|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHVDHPVYILGTIGGLAGDTDATVQR
ATPATIAANVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSASVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFIGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A7V2K888|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKTRSNLERVLEEGHFAVTAELGPPTDADAEKIKRKAKILKGYVDAFNVTDGQTAVVRMA
SWAACVIGKQEGLDPIVQMTCRDRNRIALQMDVLGVYALGIHNILCLTGDHVIFGNHPSA
KGVYDLDSIQFIQVVKTMRDEKKFQSGDEMEIEPRLFIGAAANPFADPFEYRVERLKKKV
EAGADFIQTQCVFNVKKFEEWMKRVRDEGLHERVKILAGITPIKSLGAAKYMKNKVPGMD
IPDEIIERLKGVPKKEVPKEGIKIAVETIQRMKEIEGVAGVHIMAIEWEEVVPEIIEMAG
LHPRP
>A0A7T2CFG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. JNUCC-51|TrEMBL
MGLIERLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLEQI
LATVDEQATVLLAGNPDGLLLETYYDFEELTATLSMLRAKTELPIIAQVSMHEPGILQNG
MSLNNALHELEALGADIVGVNCRLGPHHTIQAFEGVELPEKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIASAKKYLEELSPVEEKYAKPEKVEV
VREAEPANYEPLHIKVKRERSIIVELDTPRHLEIEGFIEGAKKIYEAGADVVMMADNSLA
SPRISNVAMGALLKETHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVSR
LEKKIEHGADYFISQPVYTKEKIVEIYEATKHLETPIYIGIMPVTSYKSAEFLHHEVPGI
KLSDDALSRMKACGDDKERATLEGIAIAKELVEVVAEYFNGIYLITPFLRYDMTLELMKF
IEQLDEQKKGVSING
>Q7MYD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSINRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEQTGLEAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGD
LPENSEKPKMYGSDLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFRQLKRFAVMTNVRIPSWMTRMFD
GLDDDPESANLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A7Y0J822|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. GMY02|TrEMBL
MALGTASTRTDRARTVRDMLATGKSTFSFEFWAPKTEKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVTAAGCETPVIPEVMPVTSVKMLERLPQLSNAVI
PDALKERILAAKDDPTAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A7V9F993|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexia bacterium|TrEMBL
MTHPFLDRIKAGPLLCDGAMGTYIYARGGEMDGCFDELNLTDPNAVVNIHREYIAAGADI
IETNTFGANWFKLEQHGLGDMVRDINFQGAKHARDAREVSGQPVFVAGSVGPTGRTLPPV
GMMDPKEVRAAYREQISGLLEGGVDLLMIETIGSLEEMTEAIKAAREVSDLPIVAQMTFS
ADGRTISGQSVEDVAKALQDLAIDVIGVNCSVGPRGVMRVLRAYRACLPDDMPISGQPNA
GWPTQVGDRLLYPSSPEYMGQFVTDAVNTGAQIIGGCCGTTPEHIRAMRSALDQRSGVTT
TPRDVVIETPREQQVLLPADEPTGLGRKIGKKFVVAVEIDPPRSLNPEKVLQGAQLLKDA
GVDAVNVADSPMARIRMSALALCYLIQDRIGVETILHFTTRDRNLMGLQSDLIGAHVIGV
RNIIALTGDPPSLGDYPNATPVYDIDSIGLVKVLRAMNAGTDAAGSPLGRQASFTIAVAC
DPTRDDLEEESDRLYQKVSAGGHFIMTQPIYEMVTWTHFLEVYERRHGPLTVPVLIGILP
LQSHRHAEFLFNEVPGIRPTDSARERMRLAGSQGRVEGVKIAQELLLEARDQVHGVYIMP
SFGRYEVAASVLDALSHRDLTVALS
>A0A7Y5G677|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKSDFLEALESRVLICDGAMGTMLYEAGISFDHCFDEINLSHPEIVKKIHEAYIDAGADI
IETNTFGGNRQRLGHHGLEEKLIEINQTAVRLAKEVAGKKHKQLGKKIFVAGSVGPLGKP
LEPIGKITQEEARQYFAEQISVLAENEVDVILIETMSDLNEAKAAVLAARSVTALPVIAQ
MSFNDEGKTLMGNKPLEVAKALKDAGANVVGANCSVGPQILLEVMERMSATENVHFSVQP
NAGLPRYVGGRYIYLASPDYFGEYARMFVAAGVGMIGGCCGTTPEHIRQIRKSVGESKPV
REKKIRIAADVDESPNEKSVEKLSSSSLIEKFKQKKFVVSVELDPPRGLNYDKVIEGAIL
CKKNNVDAVNIADNPLAKAGMTPLAMASLIKQNIHIETILHFSCRDRNLLAMQSELMSAH
VLNIRTVLAITGDPPVVGDYPNATGVFDVDSIGLLKLMTNLNQGIDLAGKSIGSTTNFFR
ACAINPTAVDMTREFDRYEEKIAGGAEFAMSQVMYDLKKLEEFTKRFRGRIPVMLGIMPL
KNAKHANFMHFEIPDIKIPDAIRDRMAKAGDKGQEEGVRIAKEFLKEAKDMVDGTYVMPP
FNKFEMAFEVLSVL
>A0A7V8X4S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexia bacterium|TrEMBL
AGVDAINVADSPMARVRMSAMTLCYLIQHEVDVETIIHFTTRDRSLMGLQSELLGAHAAD
VRNILALTGDPPNLGDYPESTAVYDVDSIGLIRIISRLNQGEDSFGASIGRGASFTIACA
IDPTRQDLEEEARRLHDKIESGADFVMTQPIFDVSVWTRFLKIYGEKKLPVPVMIGVLPL
QSSRHAEFLHNEVPGITLTDKARDRMRRAGSNGRQEGVQMAQELLRELVPFADGTYLMPS
FGRYEVAAEVISVLDEEPALSR
>A0A7V3DXM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MSQSTPTPAGASAAGQTTFASKLRAGQFVITCELVPPKAPDFKPLIRRCDLLRGHVDAIN
VTDCASAVLRMAPLPACHCILGQGLETILQTTCRDRNRLSLQADLIGAWAMGVRHVMALT
GDYIHLGDHPTAKPVFDLDSVNYILMLAQLKQGRFFSGEEIRITKKTPLIPMDFTLGAAA
NPFGVDLKISAMHLAKKVEAGAEFLQTQPVFDLDQFRRWAKMMDEKGLLRKVKVLAGVMP
PRSAKGLAFMKEEVPGVVIPDALIKRFETAQDPAAEGLKFAREVIDVILEHPGIAGIHFM
PVGWEEVIPELAAHCRDKRKPA
>A0A167DUI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas luteoviolacea H33|TrEMBL
MALTLQEKILDPNQGVYLIGTTPPKLGTDSEQLQTIATKLLNRLHEIEYDGVVIYDIQDE
SSRTQVPRPFPFKQTVDPVEYSKLVRDLSNLDVITYKSVAQRDRKEFTQWLQKTKQDFGL
NNLVLVGSPSSKGDVKLGLPEAYQTLREHTQDFFLGGVTIAERHANKRNEHERLIDKTTK
GCEYFISQAVYDAQATIDLLTSYARTCRQQGNEPKRIILTFTPCGGQKTLEFMQWLGISV
PEATKWRMLDADNTLNESIKICRENLDLILRSCAHLDIPLGLNIESLTNRKEEIDASINL
YRLLKATMELQLAEKQIA
>A0A3D1XWI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MSKLSEALEGKKFVVTSEIGPPKGTNIEKCLEDAELLRDKVSAINVTDIQSAVMRIGSLA
ICHLLAEKGLEPVFQMVCRDRNRLALQSDLLSAWVLGIKNVLCLTGDYTSLGDHPETKPV
FDLDSVQLLKTVATLNQGHDIAGHELDGTPNFFAGAVVTPGCDPLEPQIIKMKKKIDAGA
KFFQTQSVFEPKKFESFMNDVEKFHVPVMAGIVVLKSAGMAKFMNENVAGVFVPEEIVKE
MAETKKEDRRKKAVEIAARIIREIKPICQGAHIMPLGWDALVPEIINQAELS
>A0A1E7HMW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium S5133MH16|TrEMBL
MKSGSNLEKVLEAGHFAFTGELGPPRGTNAEEVREKAQHLKGNVDMVNITDNQTAVVRMS
SWAACLILIQEGLEPNFQMVCRDRNRLAMQADILGAYTHGVRNMLCLSGDHCMFGDHPDA
MGVFDIDSIQLVNMVKTMRDEGKFQSGGDIEDPPKIFIGAAANPFAEPYEWRVHRLAKKI
NAGVDFIQTQCIYNMDRFRKWVKQANDMGLTEKVYILAGVTPMKNVGMARYMQKKVPGIE
VPEKVIDRLKGVGKKKVADEGIKIACEQIEEFKEMKGVHGVHMMAIEWEHMVPEIAERAK
VLPRPKV
>A0A4R2CKJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2500|TrEMBL
MGEGFELVCEVEPPTRPDLKKVRHQIGVLSPIADAFLIPDNHIGRATVSSVAVANEVQAM
GARGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVRGDEPTAGGRTSELTVRTMIEQAR
ATTFPGIMPFQVGAATGLRAVPGWKAEADFLYVQVSYSLENLLRWRESVELDIPVYAGVM
VLASAKMAHNLTAALPQIAIPDDLVAAVEADRDAGVDAACEQILGIRDSGAFDGVHLVPV
SRYRQVAARLERDL
>A0A243RGU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium minutum|TrEMBL
MALGRPSILPDRVPTVRELLAAGGRSFSFEFFPPKTDEGERQLWRAIRELEALRPAFVSV
TYGAGGGTRDRTVGLVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPPGDPSGEWVRHPEGVLYADELVRLIRQAGDFCVGVAAFPYKHPRSSSVEADTEHFVR
KCRAGADYAITQMFFRADDYLRLRDRVAAKGCDTPIIPGIMPVTQMSTIARSEQLSGAPF
PAEVAARFEAVADDPAAVRRLGVEHAAELCQTLLDEGVPGIHFITFNRSSATREVYQALD
VAPADAALTA
>D2UFW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas albilineans (strain GPE PC73 / CFBP 7063)|TrEMBL
MTAISFEFYPPKTDEQRVQLDRTAARLKSYAPEYVSCTFGAGGSTLSYTSETVRHLKQQH
GFETAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEYGDTFRLEVGAYPETHPQATDALSDLRHFKTKVEAGADAAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGRRMQAYGDDAESIREFGADVV
ATLCERLIAGGAPALHFYTLNLAKPTTSILARLAMEPAHD
>A0A256CJ77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignatzschineria sp. F8392|TrEMBL
MSAQYVELLNQSLSELQNDVNVSFEFFPPNSEQMVTTLWNSIERLKVLKPQFVSVTYGAN
ASTRDRTHRVIEDIVHKTDLTAVPHLTCVDTTEAELHQIADNYWDLGIRHILALRGDLPK
GTENPGIYADHLVKLLKKRHDFEISVAAYPEIHPEAKNAQADLLHLKRKIDAGANLAITQ
FFFDIDAFLRFRDRCVAVGIEAEIVPGILPVSNYDSLVKFAGPLNVKIPSWLHKRYEGLE
NDPTTRSLVGASIAIDMVRVLRKEGIQDFHFYTLNRSELTYAICHTLGLRPDPAIGVA
>A0A1X1MX78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. qd031|TrEMBL
MGYTHAGHIDALNQNISELSDDINVSFEFFPPSSEAMEETLWKSVHRLKKLQPKFVSVTY
GANSGERDRTHSIIKEIKQETGLVAAPHLTCIDASRDELIDIANDYWANGIQSIVALRGD
IPAGGGAPEMYASDLVTLLKQQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQASRFAKMNNVKVPGWMAQQFS
GLDDDPTTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQAI
>A0A0Q6FZJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Leaf453|TrEMBL
MAHIDENPLGRHLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNSKFLSGRKLTTPPQVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGFDEKCYILCGV
GPLASAKTANWIRNNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIQGVSGVH
VMAYRQEEYVAEIVHESGVLKGRTPWKREENPGDHRVAERMESLKDGKTENPQEMADVAA
HRPH
>A0A2E8EES0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MKIRDFIAKERTILSFEFFPPKTKEDEDHLFETIRKLESFTPNFVSVTYGAGGGTQKNTR
HVVKRIKEETSLTPMAHLTCIGQHQEELTGILSDFTATGIENILALRGDPPEETTGRAPK
DRPCYAKDLVRLAASFNAFSIRVAVYPEGHFESPNLGVDMVYTKEKIDAGADFAITQMFF
DNRYFYQFMERADQAGIRVPVIPGIMPITNIEKVKRFSQMCGATLPAHLVERMEAAASPS
EARKIGIDFAIKQCENLWENGVRYFHFYTMNSSKAVAEILHGLDLGQGSNRHFPTAEESI
>A0A2H5WX01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR15|TrEMBL
MTRQEFQERLQHAVLVADGATGTMLALRGVTMPYDLANLTHPDLVRELHREYYEAGARLI
ETNTYTSNRIRLLNIPERGTELPAAQSLLEQYGSPAEVVQRVNHTGVQLAREAVGADALV
FGSMGPVGKPLEPLGEIRLQEAEQAFTEQAQALIEAGVDGIILETFTDPRELSIAVRAVR
RLAPDLPLIASKGFIEDGETLMEGLPERVARELSALEVDAIGANCVVGPQRMLDIIRMMA
HATDKPLSAMPTPGLPQLVRGQVVYDIQPEYFGRYAARLVEAGARIVGGCCGTTPEHIGA
VARAVAGIKPRQTHVSITVHPRERKPEQLPLAKPSRLSQLLGKERVITVELDLPRGLIVQ
KVIDNARLLKENGVHLIDISDGARARLRMNVMAISHLIQEQAGIEVMMHFACRDRNLLAI
QSDLLGAHALGIRNVLAITGDPAQIGDYPTATSVFDVDAIGLVRILKRFNEGIDLAGNTI
GMRANFTIAVAYNPLAPDEELERERLQRKVDEGAHLVYTQPIFEMPVVERTAELCHQLRI
PWFVGVLPLRSARHAEFMHNEVPGIRIPEGVLRRMADAPEECALEVGIEIAQQFLQQAAP
YAQGIYLMPPAGNAQIALRVLQALR
>A0A3R7F9P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MAQIRAGKFVFTGELEPEKTIDLTETLEAARRLKGYVTACNVTDNPQAFAYISSLAASYI
VQKETGVETIYQIRDRNRIAITSDLLGAGALGIKNVLALTGDHTTLGDMPQAKPVFDLDS
VQLIHMARMMVDEGVDVSGNEIKDPPKFHVGGGANPNADPLEPELIKFGKKVSAGAEFFQ
TQVVFDIETVKRFFDEIKGYNVPVLIGIFPLRSYGVAKYFDETVPGVKVPEELMKALAEA
KRIPDKKRRRQRYNEINLEYFTNLLKEIKKTTPAAGCHLMSVGYEEIIPSLVEAVK
>A0A7S9RJG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter concisus|TrEMBL
MLKEKILNKEKGLVLYGLTPPKAEFDEAKLREISERWSGRINDIKADGLVLYEVQDESER
NDSERTFEFSGTLSPEIYYKKYLNVATPSIFYRVASGYGEDEFRTALKAQSSNLNVLVGA
TSSTQKVRLNLARAYEIASEFKELTVGGVCIAERHGKKGDEPQRMREKIAAGAKFFISQA
IFDVQLARKFLEDCAAAKISEPIFLTFSTAGNAKTLEFIKWLGVSVPSLVEERLNSSSDY
LASSCEIIKEIWCELKKFGDENGLNLSINIESVMAKRTEIEASLELTKNIRELV
>A0A3E5ALT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] rectale|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNQYNVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNNTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>A0A373BTD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF28-12|TrEMBL
MNLREYLKTTNLITDGAFGTYFAAKYQTQDIPELANITATEKVKKIHEEYLNAGAKFIRT
NTFASNTETLQEDFAEVEKNIQAAVEIARDAVNGRDAWIAGDIGPIPVNGAEDAAAAADE
YYQIAKTFAECGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIGEMSLWDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLSVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTKEDAARLRRIKEETGATILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>A0A1H3MJF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoactinomyces sp. DSM 45892|TrEMBL
MKGIGILEYLKNHLVVGDGAIATYLYQQGAPVGTCYELYNLTHPKMIADVHQAYEQAGSK
LITTNTYGANRERLERYGYGHKVTRINREAVKIARESIQSDTYIAGSIGSIVAGRVTQYD
SDEYHDLYEEQATALLHAGVDIILLETFMDLQELLIAINAIRPLTDTPIVAQLSLLEVSR
TRDGHSLTDAFAQLQKHGAAGVGLNCRMGPLEIIRALEKTIVPQDLLISAFPNAGRLGES
DGELRYKSAPSYFGETAQLLINQGVSIIGGCCGTTPAHIQEIVQIAQSKTPITRINPPVV
PEACEILSQPPKRTESTVLEKVAQKRTIICEFDPPKDLDVQSFLLGSQELYKSGVDAITL
ADNSLASARMSNLALGALLKSQLGIEPLIHVSCRDRNLLGQQSHLMGLHALGIDQILVIT
GDPTRIGDLPGASSVYDVTSFELISMIKQMNQGLAFTGRPLKQQAQFIVGSAFNPHVRQI
ESAVARLEKKIQAGADYAMTQPIYDKQTIIKLYEATRHLDIPIFVGIMPITGYRNALFLH
NEVPGIKIADDVIRRFESISDPAVARQIGVEIAKDLLDTAMTYFPGIYLITPFSYWPMTV
ELTRYIREKDARAAQDSA
>A0A2N2XLZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-22|TrEMBL
CFQTDGKTLFSFEILPPLKGGTFDEIYQSIKPLLEFEPPYINVTYHQEEVIYKNHESGLL
EKKTVRKRPGTVGIAAALQYYCNVNVVPHIICGGFSKEETENALIDLHFLGVHNVLAVRG
DAERSQKEFIPEPDGHSHAVDLVKQIDPLKAA
>A0A1X3KVN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli H420|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A194XAZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mollisia scopiformis|TrEMBL
MQYPLFTMEKITDKIAALPPGSNYFSLEFFPPKTSMGSANLRARLDRMSRALRPLFVTVT
WGAGGSTAEKSLELAELCQRELGLTTCLHLTCTNMSKKLVDKALQDAKALGVRNILALRG
DPPRSEEYKERINVNGNGIEGMEEEDEFEWAIDLVKYIRKMYGDYFCIGVAAYPEGHADE
GHPEGQSLEHDLPYLVGKTQAGADFIMTQLFFDVEAYDKFEKRLREHESGAFKTIPIIPG
MMPIQSYQMIKRTTKLSHARLPPNIISRLDEVKGDDEMVKKVGVDIVSEIVTHIQQEAAP
GPRGFHFYTLNLEKAVSFILERTNLIPTEDLEDESAVLEISVPLQSLSVNGAHSNHASRR
QSSIGSDPHNRVIVTGPTSNSDWEATALDAAMPADPINTRANTLAISEGEGALGREATWD
DFPNGRWGDARSPAYGEIDGYGVSLHMSVNQAIKLWGFPKSVGDITELFIKHIEGSLSAI
PWSEEGLNEETNTIKSQLLQLNQKGWWSVASQPAVNGVRSTDPVFGWGPRNGFVFQKAFI
ELFLPSKDWTPLKEKLMSEEIKENVSWYAANASSQFFSSDSLMVNGVGTRGDEGGSTNAV
TWGAFPGKEIITPTIIEEVSFRAWAEEAFGIWEEWGRVYERESESKKLIEGVREDYWLVN
VIHHGYVEGEGLWDLLLK
>A0A150WMY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrio bacteriovorus|TrEMBL
MRVIEHLAKAQGPLFSYEIVPPPRGRSVKDIIEVVKVLAPLEPPWIDVTSHSSTTYYQEK
LDGSIQKRTLRKRPGTLGICGIIQNRFKIDTVAHILCLGFSREETEDALIELSFLGIENV
LALRGDMPNFQKPARMDRTTNSYAADLVAQIRDLNEGRFLDELDRADALGFCVGVAGYPE
KHFEAPSLKLDIMNLKKKVDAGADYVVTQMFFDNQKYYAFVEACREAGITVPIIPGIKIL
KSANQLKSVPKNFYIDLPDTLAEEVHQNPQHAEEIGKRWAQKQAEDLLNSGAPGVHFYVL
NDVHSVAEIVRKIK
>A0A1E3X9E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Scalindua rubra|TrEMBL
MSEENNTNNFKAGSNLEKLLRKGEFVVTSELGPPRGASREVVEKKAEILKGSADAFNITD
CQTAMVRLSSIASGAILINMGMEPIVQMTCRDRNRIAIQSDILGAAALGMKNLLCLTGDH
QCFGDHPDAKGVFDIDSIQLLNIVRQMRDEKKFQSGEEIKVEPKLFLGAAANPFADPFKF
RAIRLAKKIAAGTDFIQTQIIYNVKKFEEWMGIVRDMGLHEKVFILAGVTPIKSLGMAKY
MKNNVPGLDVSDEIIKTFRRGSKEKN
>A0A3D9CSJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium flavum|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREIGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAITQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A1Y5MFT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter concisus|TrEMBL
MLKEKILNKEKGLLLYGLTPPKAEFEEAKLREISERWTGRINDIKADGLVLYEVQDESER
NDSERTFEFSGTLSPEIYYKKYLNVATPSIFYRVASGYGEDEFRAALKAQSSNLNVLVGA
TSSTQKVRLNLARAYEIASEFKELAVGGVCIAERHGKKGDEPQRMREKIAAGAKFFISQA
IFDAQLARKFLEDCAAAKISEPIFLTFSTAGNAKTLEFIKWLGVSVPSLVEKRLNLSSDY
LASSCEIIKEIWCELKKFGDENGLNLSINIESVMAKRAEIEASLELTKSIRELV
>A0A356C6R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKISSIVGKDKLTLSFEVFPPKTDSDFEKVKEAAFGVAAIKPAYISVTYGAGGSTSTNTL
AIAKGIQEKYGVATIAHLTCVGASKDSIIKSLSDMRDAGIENVLALRGDKPKWFDGEPFK
EYKYASELVSTIKEFGGFSVGGACYPEVHPDSANRQEDIINLKKKVDAGCEFLTTQMFFD
NSVYYDFVENVRKAGIDVPVIPGIMPITRESQIENVIKLSGCKMPQQFIKIVDRFKEDKA
SMKQAGIIYATQQILDLYANGVKNVHVYSMNDSSVAGAIYNNLSDILSM
>A0A6I7WWN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium HT4|TrEMBL
MTIKNKADLFSFEFYPPKTEQGDLNLEQVHRDLAKLNPDFFSVTFGAGGSTRDKTYDTVV
KIQKNGVSAAPHLSCVASTKENIREILANYREHGVSKIVALRGDLPSGMMSAGEFRFANE
LVDFIRAETGDHFQIHVAGYPEVHPQAGNATEDFNNFKRKVDAGADAVITQYFYNAEAYF
YFLDKCEKSGINIPIVPGIMPITNYAQLFRFSGMCGADIPRWMRKTLECFGDDKASIMAF
GEDVVSKLCQELLDNGAPGLHFYTMNQSKPTLAVWDNLSFA
>A0A3A4R7R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aureabacteria bacterium SURF_26|TrEMBL
MSKGDSMTESFKDILRDENRIILFDGAMGTYLYQKGFFLNINFEQLNITNPDTIREVHEE
YIKAGADVIKTNTFGANSFKLEKAGLLDQLADINRAGVKLARECAKKAQTFVAGSVGPIG
KLVHPLGPITGTQARSIYEEQIEILIDAGVDIITLETFTDLRELQIAVETVKKISSDVPV
IAHLSVTEDGTSILGATPDQLAELAYKLNIDAVGFNCSVGPHHMLKPIEHMKQYKDLVIS
VHPNAGVPRIIDDRSFYLTTPEYFTEYARRYLLNNVRIVGGCCGIHPEHIKQLKYIVKSV
VLGIVAAEEKDQSEISVQGEHPGMEPVPASERSHFAKRLCRGDFVSSVEITPPKGCDPTK
VIEAARYLKAHGVDAVNIPDGPRASARMGPQMLAIILEREVKMETIIHYCCRDRNVIGMQ
SDLLGVAAAGLRNILAITGDPPKLGHYPNATAVFDVDAIGLVRIINKLNHGLDLADNDIS
NTTKFFVGVGVNPVASNYELELARFFRKVESGADFAVTQPVFDPDRLNKFLDDIHDIDIP
VLIGIWPLASYRNAEFLNSEIPEITIPDYILERMKKVTDKEAAKLEGVAIARETLFSLKS
RIQGVQVSAPFGRADLAVKVLEGIITPDPEYHTE
>A0A2A9CJU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. es.036|TrEMBL
MSLLEDLEHKILIGDGAMGTLLYSYGIDQCFEALNLSHPDQVLNVHQAYVHAGSDVIQTN
TYGANYSKLSRYGLEDLVKEINKEGVKLARKAATDSTYVLGTIGGIRGINTRSTPLDEIK
RSFREQLYCLLLEGVDGLLLETYYDLEEIITVLKIARKETDLPLIAQVSMHEPGILQDGT
SLAAALKQIENAGADVTGVNCRLGPYHMIQSLEQVPLSGRFLSAYPNASLPEYEEGRLVY
PTAQDYFKQSAETLRQQGVRLIGGCCGTTPEHIAAAANALKGLKPITTKEVTVNEKEARI
IDFEEERLPHLHEIARKQRSVIVELDPPKKLSIDKYLEGTKALQEVGVDAITLADNSLAS
PRICNTAMASTIKAQHNVRPLVHVACRDRNLIGLQSHLMGLHTLGINQVLAVTGDPTKIG
DFPGATSVYDVSSFDLIRLMKQFNQGRSYSGKSLGIKTSFSIAAAFNPNVRHLDRAVERL
EKKQQCGADYFISQPIYNEEQLLEVYEATKHLTCPIYIGIMPLTSYRNAEFLHNEVPGIK
LSDSIRNRMLHATDSTQSIEAGLAIAKSLIDAAFDLFNGIYLITPFLRYELTVELTRYIN
EKTRLEEERKNRNGLHLI
>A0A167UEH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium chrysogenum|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKVLGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRQTHGDYFCVGVAAYPEGHPADNFQDVQDPARDIPS
LVEKTQAGADFIMTQLTYDIDAYQKFEEMLRNHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIAKRMEELKHDDDAVKRAGVDIVSEIVGGVRDIPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPSYSDAGDTAIADDPASIPLDFPGRALRRRRASSINSQPHNRVIVDKL
SVHESSQDSVHEALADSAGVPAPPPNRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTANTARRLWGHPVDSKDMSAIFRRHVSGELHMVPWSEGGAEEDGEG
LNAETELIRPELLKLIDGRGWWTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFC
SSNDYTNILKPLFAKHGHDKLTWFATNVKGDFESSLPAQPADMDLDDLGSNPESVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTETYLDTTKNDSWLVCVV
GQQFGAGTKQGSKEEEDEVKWMWRVLAGEEA
>A0A4P6V7A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseitalea porphyridii|TrEMBL
MALTGDIRVSFEFFPPKTEAMEATLADTIEKLAPLSADFVSVTYGAGGSTREPTRRTLAH
VQKQGGMDAAAHITCVGSTCEETDAVVREFTAMGIRRFVALRGDPQTGMGTRYVPHPGGY
ENAAHLVAGLKAFGDLDISVAAYPEKHPESPDFATDIDMLKRKVDNGASRAITQFFFDND
TYERYVERARKAGIYVPIVPGILPIHNFRAVSNFAGKCRTHIPAWLAERFDGLENDPKTH
ALIASAIAAEQVLDLVDRGVRDFHFYTMNRPDLVFAVCRLIGIREETVDAAA
>A0A2A5YK63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium MED-G05|TrEMBL
MASTIEMISKAATDWSIEVTPTGATKIESFRDCLPPGTTVNVTFLPGTDPAETIAVAERL
HNDGMRPVPHLAARSLRDADQLDELLTAFTSRCGVDEVLCIGGGVDKPVGTFDATIQVLE
AGLIQKHGIRSVGVAGHPEGSPDISDEEVAEALAAKNALAARDGLNLYIETQFCFEADIV
LDWERRVRAAGNTLPIRIGIPGPATIKTLFRFAQISGIGPSMRFIAKQAKNVAKLMTVQS
PHMLIAGLAEGMAADDACLIRHFHYYPFGGFARTAAYAGAIAEGNIELLPKGGFDVIAN
>A0A167YU27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium chrysogenum|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPVEKVDQALQAAYKAGCTNILALRGDPPREKEA
WEAAENGFCYAKDLVKYIREKYGNHFDIGVGGYPEGADDNTDVDQLIDHLKEKVDAGSSF
VVTQMFYDAENFIEWVKKCRAKGINVPIIPGIMPIQTYASFIRRSNWTKVKVPSEWMEAL
EPVKNDDSAVRDIGKTLIANMCRQLIAAGIKHLHFYTMNLAQATQLVLKELELTPSEDSP
IQRPLPWRPSLGLGRRSEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISDIFVNFLTGKLDRLPWSDSPITTEAHEIQEDLLK
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKND
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCHDAASPSRQLIQHVMEDWYLVNIVDNDFHRSNAVFELFNGLEIKDLNVEVTGKPLTNG
HAEPNGVAAN
>A0A2I3CBS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio alginolyticus (strain ATCC 17749 / DSM 2171 / NBRC 15630 / NCIMB 1903 / NCTC 12160 / XII-53)|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSAKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKATTGLVAAPHLTCIDATREELINIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFD
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRAVVGA
>A0A1B3N6F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomonas sp. RAC04|TrEMBL
MTLSLKQLAEAREALGTPLFAGLAGDVEVSFEFFPPKTEKMEETLWDTLTTLAPLKPKFV
SVTYGAGGSTRERTHATVARIAAETAIPAAAHLTCVDATRDEIDEIAQNYWNAGVRHIVA
LRGDPPRAGEKFSPHPGGYANAAELVTGLKKVAPFEISVAAYPETHPDADCADSDIDNLK
RKIDAGADQAISQFFFSPEAFFRFRDAYTKAGITKPILPGILPVSNVATTRKIAGMCGTA
IPQWMNDLFEGLDDHPTTRQLVAATVAAELCRRLYSGGVRHFHFYTLNRAELSFAICHLL
GLRANRHAQAAPVLQENAA
>A0A357T5Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
LPFAEHLQELGIEEVLVLTGDPPQDMSRKIYPSDSIDLIRKFKREHPQIKVYAAIDQYRT
SMRMEYDNIKRKLDAGADGFFTQPFFDLRLMQIYAEMLQGLEVFWGVSPVTSEKSVNYWE
TKNHLIFPAGFEPTLEWNLRFAKQALKFTEELNAHIYFMPIRTKLQVFLGGLFD
>A0A4Q5ZK56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcaceae bacterium|TrEMBL
MSQPTKSTIRAPRQPCFSFEFFPPKTDAGVASLLRTVEELAPLNPGFVSVTYGAGGSTRD
RTVDLVTHIKQHTGIEAMAHLTCVGHDRDELRDVLRRLDAARIENLLLLRGDPPQGQQTY
EPVPGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLKHLKAKVDAGMDFVV
TQLFFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMER
VKDQPDAVVQLGVAHATVQCVELLARGVPGIHFYTLNKSPATRMIVSALRARS
>A0A5C8B727|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MKTHNFSIEFFPPKTEDGTQKLRATRAKLAELNPKYFSVTFGAGGTTQQGTLDTVVEIRN
EGFDAAPHLSCVGGSKESIRQILKTYQSHDIRRLVALRGDLPSGYGMGGEFRYANELVEF
IRAESGDWFHIEVAAYPEMHPQARSPQDDLNNFVRKVKAGANAAITQYFYNADAYFQFVD
NAQKAGVDVPIVAGIMPITNSSQLMRFSEMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTQMCERLLAGGAPGLHFYSLNQAAATTEIWKRLLA
>A0A353N3T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MKPEEELSRMLKKIELGATFFLTQPLFYERVMDFLPQVTTEQNIGGIMPLVSYNNAQFLN
NESGWYSNSGAN
>A0A5C5EBX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus shcherbakoviae subsp. psychrophilus|TrEMBL
MKIRDMISKGEPTVSFEIFPPKSSYSLETVFDTLGELKDLHPDFISVTYGAGGTAQSNTV
EIASRIKKDFGIESIAHLTGCTSTKEGMKRTLASIKDSGIENILALRGDIPQEKLADKNW
NPEYRYASELIDDIKAAGDFSIGAACYPEGHVDSINKVDDLKNLKRKMDHGADFMITQLF
YDNDLFYQFKEKLDLVGIEQPVIAGILPVLNIKQVKRIQEISGCNLPPKFLRILERYEHD
PASLQEAGIAYAVDQIIDLLSSGVDGVHIYTMNKPDATRRIMENISCVRKAVCRKEPQR
>A0A2W4QFM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MQGQGGSAMARFMHRLRQGAFCVTVEIDPPRGAGVAQTLERVRRFADRVDAVNVADCPMA
NVRMSPITLAHLLQRDGQVEAIFHLTTRDRNIIGLQAELLGAAGLGVRNILALRGDDPSQ
GDHPQARGVFEVDTVGLIRLAAALNRGQTLSGTPLDQGTDFAIGCACNPAAADLEAEVSR
LEEKVEAGAHFAQTQPVYDPRQVERFQAKLAGRVKIPILYGILPLRSYEFADRLNRTVPG
IVIPDRILDRMRARGEEEGLRIVAELLREIGPNVHGVHIFPMNSARRAVAVLDLIDELGL
RRAARVGVSAS
>A0A481QKN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pseudomonas adelgestsugas|TrEMBL
MFQNRRYSFEFFPTKTDAGHKKLMTIAKQLASYNPDFFSCTYGAGGSTRNSTMKTVLQLE
NEIKISTAPHLSCIGDSKANLRSLLTQYKQAGIKRIVALRGDLSLDMSMSSGELCYANDL
VSFIRQESGDHFHIEIAAYPEMHPQARNFEDDLKNFIRKANSGANSAITQYFFNTDSYFY
FIERILAMGVDIPIVPGIMPITNYNKLARFSKACGAEIPRWICKQLEVYGEDVKSTKAFG
EQVISNMCEQLLQGGAPGLHFYTMNLAEPSQAILDSLKRLD
>R7I359|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:411|TrEMBL
MDIREYLKQHKILADGAMGTYYATLHNGEVSEFANLENPKAVENIHLNYLKAGVNMLITN
TFAANEQSMGTVWKQVQACINAGIAIAKSAKEKSGREDVFLAGDIGPLQVVGEKTEEQLL
VEYKRIIDLYLEAELPVILFETFSSLYFVEPLVRYIRERNKDVFIIVSLSVNKNGYTATG
LSARRLLEELISMDEVDACGLNCGIGSGHMLQLAQDLQDLFEQKYFMIMPNAGYPEQLRH
RMVFMDNANYFADNMQEIAKMNVAILGGCCGTTPEYLFTLEKKMDFSPAVIMKTTSNSDE
VKDVVRKPKKKNKFYEKFSSGNKVVAVELDPPYDANCDKIMECAMHLKDCNVDMITIADS
PMGRSRVDSILMSIKLAQETELPVMPHLCCRDKNMIAMRSGILGAYVNKIRNLLLVTGDP
VPSVNRNVTTGVFDYHSIRLMNFVKEMNEEHFADDPIYYGGALNYGRGKIENVAKRMQQK
VDAGCSYFLTQPIYSDEDIERIRMLKSMVDTKILCGIMPLVSYRNANFIKNEMSGINVPD
EIVERYTPDMTKEEAEVVGAQIASEIIEKLSEFADGYYFMLPFNRVSLMDKIIIK
>A0A7W7Z3N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas rhenobacensis|TrEMBL
MTELMPATRPAISFEFFPPKTEEMERTLWEAISRLAPLAPNFVSVTYGAGGSTRERTHAT
IARLLNETSLTPAAHLTCVDAPKADVDDVVARYHEVGVRHIVALRGDPSSGLGNSYAAHP
QGYQHSYDLVAAIKRRYADIEVTVSAYPEKHPESANFDADIDMLQAKIDAGATRAITQCF
FDNELYLRYLDRVRARGISIPIVPGILPVQSFKQAANFAARTGTSIPAWFAEKFEGLDDD
PDTRKLVAATVAAGQVQKLAKHGVDSFHFYTMNRADLVFAISHLLGFRPNGARKAA
>Q7U409|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasynechococcus marenigrum (strain WH8102)|TrEMBL
MTTALQRAIESGQQAMTAEVMPPRGGDPSHTLAMADHLKGRVHAVNVTDGSRAVMRMSSL
AVCRLLLDRGLEPVLQLACRDRNRLALQADLLGAHALGIHNLLCLTGDPVRAGDQADARP
VNEFESVKLLRQVTAFNQGKDPVKADLPDGATQLFAGCAADPQSRSWSGLQRRLHRKHEA
GARFVQTQMVMDPSALERFQVELAEPLNLPVLAGVFLLKSAKNARFINRVVPGACIPEDL
ILRLESADNPAMEGVAIAAEQVKRYLGIVQGVHLMAIKAEERIPLVLDQAGVNQLAA
>A0A2W4TKE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium|TrEMBL
MPKLSFELYPPKTDDQRAQLDRTVRKLKVYSPEFVSVTFGAGGSTLSYTAETVRGLRDDH
GLNGVPHLSCVGGTREEIGQLLSEYRAQGCDRIVALRGDLPSGMARAGDLHYASDLVRFI
REEHGDHFHIEVGCYPETHPQSEDAMACIRHFKTKVDAGANSAITQYFFNADAYFRFLDD
VRKAGITVPVLPGIMPISNFSQLRRFSEACGAEIPRWIGKRMQAYGDDADSVREFAADIV
AGMCRRLVDAGVPELHFYTLNLARPTEAVLTRLG
>A0A5C7R7G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium|TrEMBL
MTPISFEFYPPKTDEQRTLLDRSASKLKAHAPEYVSCTFGAGGSTLAYTSDTVRRLRQEH
GFDAAPHISCMGGSREEIRELLLLYRALGCRRLVALRGDLPSGMARMGDLRYASDLIAFI
RAEHGDHFHIEVGCYPEVHPQAEDALADLRHFKTKVDAGANGAITQYFYNPDAYFRFVDD
VRKLGVSVPVVPGIMPISNFSQLKRFSDACGAEIPRWIGKRMQALGDDVEGIREFAADVV
AGLCSRLIEGGAPSLHFYTLNLAKPTQAVLARLKDRLAD
>A6C2T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia maris DSM 8797|TrEMBL
MRISELYQGGTFGLSVEIFPPRNESGDAELFKTLEELVRYQPAFVSCTYGAGGSTSKRTI
ELCALIQNQLHNTATAHFTCVNSTREELVEWLQNAVDAGITNIMALRGDPPAGQETFVPA
DGGLKYANELVSLIRKHFPDMGIGVAGYPECHPEASDAEVDLTNLKRKVDAGADAIYTQL
FFNNEHFYQFRERCLKAGIDRPIVPGIMPITEYRRIQRIMSMCSSEFPADLVGQLEAAQD
DLEAQFEIGVEYAIRQCEQLIKEGVPGIHFYVLNRSQACKRIFDALGFPETQENIAT
>A0A421KZB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium sp. wkB344|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLMPDFISVTYGTGRRSDRTATARIAKTIH
TEYGIPAVAHLTAQYADREVIDQALDMFDDAGVAAVLALRGDSVEGREPAGVFDHASDLA
AYIRSRRPNLSIYGACYPETHPEAASPEEDIENLKIKVDSGVDHLVSQLFYDNADFLDFL
DRARAAGIQVPIEAGIMPITNEGQVRHMSEVCKARIPAAVESILERWGDDRASLREAGII
YASQQIADLVAHGVDGIHLYSMNHSGVTRRIWHNVRHLFRQVGAKEEPVSSQK
>A0A7Y0G877|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp|TrEMBL
MTLPISFEFFPPKTAEGADKLRLTRQALYSHRPEFCSVTFGAGGSTQEGTFGTVREILEE
GVAAACHFSCVGATKATVRQQLAVLQAMGVKRLVALRGDLPSGYGIGGEFHYASDLVAFI
RAETGEAFHIEVGAYPEIHPQAKSADADLKAFVTKVKAGANSAITQYFFNADAYLRFVDD
ARRLGADVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTLSIRSFGLDVM
TALCEQLCTAGVPGIHFYTMNQAAATTEIIRRLKLA
>A0A6A6BAV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aplosporella prunicola CBS 121167|TrEMBL
MEKITDKIAALAPDQSYFSLEFFPPKTQMGFANLQNRLERMSRGLRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRSLVDDALEQAKALGVRNILALRGDPPRSEE
YRDGGQAENVAADNDSNAEFTWAVDLVKYIRANYGDYFCVGVAAYPEGHSDQSHPDKQHP
KFDLPYLVEKVQAGADFIMTQLFFDVHAYEAFEDMLRNDASGAFKTIPIVPGLMPIQSYQ
ILRRTTKLSHAKLPEDMLTRLDAVKGDDEAVKAAGVEILSEVVERLKKKKRGAAGPRGFH
FYTLNLEKAVAHIVERCHLISTISAEEAAAENEEAVTIDDVVSAVPPADALSSNYRRRLS
SANSTPHNRVVVQRPSASSNKSYEALQEEAGVPRDTIISRANTLAISEGEGSLGREATWD
DFPNGRWGDARSPAFGEIDGYGVSLHVSVPQAIRLWAYPAEVADISDIFRRHIVGELEAI
PWSEDALNEETLTIRDELLGLIKRGWWSVASQPAVNGVKSTDPVFGWGPRNGFVFQKPFV
EFFLPSADWRKLKARLDQIEEVTYFAGNHAGEFDASDEESVNPVTWGSFAGKEITTPTII
EAVSFRAWLEEAFGIWAEWRHIYPPGSATAKLLGGIRDDYFLVNVIHHDFVEKDALWGLL
LGE
>A0A8I3ASA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium longisporum|TrEMBL
MVTTPYSEALPTFWNGLLPLPPLLHLEMLADAERDGQPSFSFEYFPPKTAQGVQNLYDRM
DRMYNFGPKFIDITWGAGGRIAELTCEMVTQAQSVYGLETCMHLTCTDMGLEKVNDALRK
AYKAGCTNILALRGDPPREKEKWVAADGGFEYARDLVKHIRATYHDHFDIGVAGYPEGCD
DNKDEESLLDHLKEKVDMGATFIVTQMFYDADNFVRWVGKVRERGITIPIVPGIMPIATY
ASFMRRAKHMNCSVPQEFMDALEPVKNDDNAVREVGKVLVAGMCRKILAAGIHHLHFXTR
MVLEELNWMPTSERPLKQALPWKQSLGLGRREEDVRPIFWKGRNKSYILRTQDWDEFPNG
RWGDSRSPAFGELDAYGIGLTGTNEQNIKKWGEPQTVQDIATLFVRYLQNEIDCLPWSES
PLTNEADPIREDLIALNKRGIITINSQPAVNGVKSSHAVHGWGPKNGYVYQKSYLEMLVH
PDLYPEIISRIEKHPDMTYYAVTKSGNLKYNAPSDGPNAVTWGVFPGKEIVQPTIVEGIS
FVAWKDEAFRLGLDWAHCFEQSSPSLNNDFHQQREIFDLFEGLSVKEYDDIKPVVKDVAP
DAVSAPTNGTTNGIAVPAA
>A0A0G4MXB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium longisporum|TrEMBL
MQQWWSRTSYAMQRERDSPAHADSEFATIADSEDPGISFNLKFQPKEDINPLTATVGSFF
KNAPKVAILREVGVNSHAEMAFAFKAAGFDPIDVHMSDILAGRSLREFVDKIAALPANAN
YFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGSTAFKSLELAEICQRELG
LTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPPRKAEYQDAVDEESDDDEDFV
WATDLVKRESQXEPEWRGYHKPIMIAGGVGTVRPQHALKDPKDVNDGAHVIVLGGPAMLI
GLGGGAASSAASTEDTAELDFASVQRGNPEMERRAQMVIDTCVSLGDESPIAFIHDVGAG
GLSNALPELVKDAGFGGKFELRQVHTDDKSLSPLQLWANESQERYVLLVNKDSLNRFVSI
CRRERCPFSDVGTVLAEDENGNSKLILSDRDSTEHPLPIDLPMSALFPPGRRLERVVERR
ELDLPAFNAVASLKSALSDTASNAHLITAATERVFRMPAVGSKSFLITIGDRTVGGLTVR
DQMVGPWQTPVADCAVTATSDTASNAHLITAATERVFRMPAVGSKSFLITIGDRTVGGLT
VRDQMVGPWQTPVADCAVTATSYQIGSSKRTGEAMAMGERPQLALISAAASARMAVAESL
LNLGAADIIGELNRVKLSANWMAAVNHPGEGARLYEAVHAIGKELCPELKISIPVGKDST
SMKASWKDRESGKAQSVTAPVSAIITAVSVVEDVRRTWTPQLRRVEDVGETILVYVDLAE
GKQAMGGSALAQSFGQLGNEAPDVRNVGLITDYFDALKQLHESGVSVTAPVSAIITAVSV
VEDVRRTWTPQLRRVEDVGETILMYVDLAEGKQAMGGSALAQSFGQLGNEAPDVRNVGLI
TDYFDALKQLHESGVVLAYHDRSDGGLITTIAEMMFAGRCGVELLLDGVAKSGSAADVLE
ALFNEELGAVFQVRKSDETNFKRCFATCGPPKGLIRKIGVVKATSKQELTIRYQDPTPIV
NLDRVEMQQWWSRTSYAMQRERDSPAHADSEFATIADSEDPGISFNLKFQPKEDINPLTA
TVGSFFKNAPKVAILREVGVNSHAEMAFAFKAAGFDPIDVHMSDILAGRSLREFVGLAAG
GGFSYGDVFGAGVGWAQSILEHKHARQEFEAFFNRPDTFSLGVCNGCQMITRLKELIPGA
ADWPTFSHNASRQFEARFGMVTIDDSRAATPSVFLHGMSGSSLPIAVSHGEGRATFASPT
QLDTLGAEGLAPLRYVDNRRRIAEPECYPANPNGSPGGVAGVRSKDGRVLALMPHPERTI
MADVASYVPPSQIEEWGEFGPWVRMFKSARRWVG
>A0A6L5Y845|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hornefia butyriciproducens|TrEMBL
MNLKDLFNGEKTVFSFEIFPPKRDADINTIYTTLDQLHYLDPDFISVTYGASGSLANNST
CEIASAIKKQYCLEAAAHLTCVNSTREEIDIMLERLANAGIDNILALRGDRVPDVPPKED
FPHASDLIRYIRASHYDFGISAACYPEGHPDSPDMIDDIRNLKLKVDAGAEHLISQLFLD
NGMFYSFLEKARIAGINVPIEAGIMPVVNKKQIERMVTLCGATLPEKFIKMMEKFEHKPE
AMRDAGIAYATNQIVDLLAHGVDGIHLYTMNNPYIARRICQNVKTLF
>A0A7G5BTI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella cholangitidis|TrEMBL
MKPDLRTALALKPLVGDGAMATYLYQLGLPVGVSFEEFNLLKPDVIAEVHRRYAAAGAEI
IETNTYSAQQNKLAKYGLEKKTEEINAAGVAIARKAVGQDAYVVGSIGAVRGGAGKNVRT
AIVKRDFEEQIGVLLGSGVDGLLLETFFDLEELSLALSIIRKQSDISVICQFAVEDAQRT
HDGIPLPEAFRRLKGEGADVIGFNCRSGPNGILRALETIPRDLGVPLSVFPNAGIPDYVD
GQVIYSATPEYFASSAIKFANAGARVIGGCCGTTPEHISAIAGALKGYAPVVQPIIPEDA
QPGKPVEVVDVQPAVAGDGNEPPQDAEPSIVDLVRQRHTVIVELDPPRDLDISKFMAGAQ
ALKEAKADALTMADNSLAVTRMSNMALAALLKERVGIRPLAHIACRDRNLIGTQTHMMGF
DALGIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKAKFV
VGAAFNPNVKHLDKAVQRLERKISAGADYIMTQPVYDPELIVRVAEMTKHLSIPIFIGVF
PLASGRNAEYLHNEVPGIQLSDSVRQRMSGLEGAARAEGVKIAEELLDVAMEHFNGIYLM
TPFMAYEMTVSLTEYVRNKSKSIHSGK
>A0A1F9LFU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYC2_FULL_48_10|TrEMBL
MKELKSGSNLEKVLNAGHFAFTGECGPPKGANVEHLNEKLNHLVGVVDAVNMTDNQTAVV
RMSSIAGSVLMMKKGLEPNFQMVCRDRNRLAMMSDVLGAYAMGIRNMLCLSGDHTSFGNH
PEAKGVHDIDSMQLIAMVKKMRDEGKFLNGEDIDGPPKLFIGAASNPFGDPFEYRVFRLA
KKIQAGVDFVQTQCIFNMEKFREFMKQAVDMGLHEKCYILAGVTPMKSAGMA
>A0A345YHR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter aureus|TrEMBL
MREAQRALETPLFSGLSGDIEVSFEFFPPKNERMNETLWHSVETLAPLGPRFASVTYGAG
GSTRERTHQQVVRIQKEAHIPAAAHLTCVEATREQVDEVARHYWDEGIRHIVALRGDPPD
GANKYTPHPGGYANAVELIAGLKKVADFEISVAAYPEVHPDSPDAQADIDNLKAKFDAGA
TRAITQFFFDPQCFFEFRDKAAAAGIAGEIVPGIMPVLSFAAVQRMSGLCGTAIPHWMEG
LFDGLDDRPEARKLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKV
>I0IN70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospirillum ferrooxidans (strain C2-3)|TrEMBL
MTFREALTAHSFMITGECSPPKGTLVAPLLERLVALKGRVHGLNITDNQTGVMRMCPLAM
GVHLQSIGIDPIVQITLRDRNRLAIQSDILGMSSLGIRQALCLSGDPPTLGDHPEAKPVF
DLPTPELIRAITLLNGGTDLSGKDLSGPTDILPGAATSPEGDFDAETRKFEEKFSAGARF
FQTQAVFSPKTMERFMVFASPFRVPVLAGIILLKSARMANYLNEKVPGITVPKELIARLE
RAPQGGALDVGIEIAAETIRAIRPMVHGVHIMTVGAEETIPRILDLAEC
>A0A2S1YJF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium crocinum|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAVDLVKQIKDLNCGQYLHEVIDTDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A4P7P133|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenovibrio crunogenus|TrEMBL
MQSQQKYEQKLSLEFFPPRTEKGVEKLKTVIEELGTINPEYMSVTYGAGGTTQNRTIETV
EYIQTQTAFDAAPHLTCIGASEESVLELLDRYEAMGIKRIVALRGDLPSGMMDPGEFKYA
SDLIAFIRQERGDTFKLEVAAYPETHPQARNCDIGIKWFKHKVDQGADSAITQYFYNVDS
YLYFIDNCERSGIDLPIVPGIMPITNYENLIRFSEGCGAEVPRWLKCRLESFGDDTDSLK
AFGEDVVTELSQRLLDAGAPGLHFYSMNQSAPTLNIVNALTFKNT
>A0A1J4P120|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces mangrovisoli|TrEMBL
MKTTSIPPSTGVALLRDFSLEMTGKDTSKLGEARQSIPPGTRINVTYLGNEDLALRLDAA
TTARDLGFVPVPHISARRLASEAALREFLTALRAHGVQEQVFAVGGDPAQAHGPYDDSLQ
IIRSRLLQEHGVRRVGISGYPEGHPQIPDVTLWAALTDKAAAMTEGDLDGDIITQFGFDA
DPVLAWIEEVRARGIHLPVRVGVPGPAGVKRLLAFATRFGVGTSTSIARKYGLSLTNLMG
TAGPDRFLRALAAGYDVARHGDVKLHFYTFGGLGATSTWIDTFRDKEGLK
>A0A0G4M4H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium longisporum|TrEMBL
MDKITDKIAALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
AFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPPRKAE
YQDAVDEESDDDEDFVWATDLVKYIRKNHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVEKTQAGADFIMTQLFFDIDAYDHFEQVLREHPSGAFKTIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDALMARLDAVKGDDEKVKEVGVDIVSELVDQIRAVKSKRTTGPQGFHFYTL
NLEKAVSFILERTNLIPDKEQEDEEAVIDDATTPPVVPTVQINGLHPGSHHRPGRRQSSI
GSDPHNRVIVSSASNHAYETNPEGAGLPAEPINTRANTLAISEGEGVLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVTQAVRLWGHPKSSEDISTLFIKHIRGELSAIPWSEE
GLSPETNIIQEQLIELNTRGWWTVASQPAVNGVPSRDATFGWGPSHGFVFQKAFVELFLP
AADWKVLSERLTGPEVEGTVCFYACNGNGDFATSDDSGGLVRTAVPASTNAVTWGVFPGK
EIITPTIIEEVSFRAWSEEAFKIWGEWSRVYGRGHESEKFLKSVKDEYWLVNIIHHDFVE
TNALWDLLRG
>A0A1M7L2F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus flavefaciens|TrEMBL
MKTAELFEQKTVFSLEVFPPKPDADESVIYQTLEQLSDIQPDFISVTYGAGGGKNGCKTI
QIASDIQSRYGVESVAHMPCINLKKEQAAEILDSMQENGIENILALRGDRTDDSAPNGDF
HHASDLINFIKDNYDFNIIAACYPEIHPESTSAVDDLKWLRYKVDCGADHLISQLFLDNH
RFFDFREKACIAGINAPIEAGIMPVTNKRQIERMVKLCGVELPQKFVRVLEKYEHNETAL
RDAGIAYAIDQITELIAEGVDGIHLYTMNNSYIAHKIFDAVQSLISVSSFC
>A0A822WZF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter bugandensis|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKNVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1S3X4U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nicotiana tabacum|TrEMBL
MKVIDKINESAKTDRVVFSFEFFPPKTEDGVDNLFERMERMVSHNPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPATGIATQETYENDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPADITAALEPIKDNEEAVKAYGIHQATEMCKKILATGIKTLHLYTLNMEKSALAILMNL
GLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDEYPHGRWGNAQNP
SYGALSDYQFMRARSRDKKLQEEWAVALNSVEDIYERFMNYCLGKLRSCPWSELDGLQPE
TKIIDEHLGNINTKGFLTINSQPAVNGAKSDAPSIGWGGPGGYVYQKAYLEFFCSHEKLN
ALVEKCKAFPFLTYMAVNKEGNWISNANQTNVNAVTWGVFPGKEIVQPTVVDPASFMVWK
DEAFEIWSRGWAQLFQESDPSRKLLEQVQNSYFLVSLVDNDYINGDLFAIFKDI
>A0A8I3MFB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Canis lupus familiaris|TrEMBL
MDQPPPGVLPATVRCSRLGLWTLEAGRVGFSVPPSISRSPAMVKEPRGDGDGGPTPRSEG
SSSGSESSKDSSRCSTPGLDPERHERLREKMRRRMESGDRWFSLEFFPPRTAEGAVNLIS
RFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQI
TGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYP
KGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFP
IQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGL
HFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRT
QEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARY
LSGEPNQHGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIV
GWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNA
VTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFL
VNLVDNEFPLDNCLWQVVEDTFELLKGPSPEREAEAV
>A0A432IST3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MEYQSLLHKKLSEGIFVFTAETTPPDASNQEVLLKKTMPLKGVADAVNVTDSPGAKVHMS
SLTAAIILAQNDIEPILQLTVRDRNRLALQGDLVGASALGVHNILCLSGDDPKVGDQPET
KPVQDINSATLVTTANLMRKDKQFPSGRIIDPPPKLFIGAAEVPSKGKPNTKKILNKIKI
GVDFFQTQYIFEKKKLIDYMKVLDDVGILEKTYFIIGLGPFASAKSAKWMNDNLFGVDVP
DEIIKRLEQAKDQKEESKKICLELIQIFREIKGVKGIHLMGHKKEELIAEIIKESKII
>A0A7C2EXU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTEKRRAVSFEVFPARTPKGEAALDRALQQLSKLRPGYLSVTYGADGSGQERSVHLIERL
SGKKEFRIAAHLTCVGATRAQIDELARRWSELGVRRVVALRGDVPGGGPWLPQADGYQNA
ADLVAGLRRVADFNIAVAGYPEVHPDSPSVEADIENLKRKQDAGASVIITQYCFDNEPFL
RFRERAVAAGITIPIVPGVLPVTNFAKVVEFSRKCGATVPAWLAEQFDGLDDDPETRAMV
AASVAVDQCKALRAEGFDRFHFYTLNRAAVTHAICRRLGIHPGVAEAA
>A0A3B9FEX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
KISFEFFPPKSLQASFNLWESLNVLAPLNPEFVSVTYGAGGTTRQLTREMTETIGKNYGL
DVAAHLTCVNASKVETLAIAKSYVDAGVKQIVALRGDAPKGSGGFRPHPNGFIDSVDLVA
GLAAANIKTIHVGAYPEPHPEARH
>A0A257F1U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium PARR1|TrEMBL
MTAPRISFEFFPPQTLDACFRLWETVQALAPAKPNFVSVTYGAGGTTRKLTHEAVSTIGK
NYGLNVAAHLTCVDATRAETLEIAESYAAAGVTEIVALRGDAPKGAERFTAHPEGFASSV
ELVEALAKTGKFKIRVGAYPEPHPDAKDRFADVTWLKRKIDAGATSAITQFFFEADTFFR
FRDACVKAGIDAPIIPGILPIISWDGAKKFAARCGTQVPGRLDEAFQTAARDGREELLSL
TQCTTLCTRLIEGGVQDLHFYTLNRPHLTREVVRALGINQDVALEKVA
>A0A0Q6R2X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Root329|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQSFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A0U5P0Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. C105KSO13|TrEMBL
MKIIDKLKEDRIHISFEVFPPKTDAGFDNVLQATDRIAELKPDFISVTYGAGGGTSKNTA
EIARHIKEDLGVESLAHLTCASSTKKEVRSVIKNLKELGIENILALRGDIPENSSFPSDD
RFRHASELVTEIHNYGDFCIGAACYPEGHPESQYSKEDIRFLKKKVDRGVDFLTTQMFFE
NDIHYNFLYRIREAGITVPVLPGIMPITSAKQIKRSIELSGTVFPRRFLAIADRFGDCPE
AMQQAGIAYAVDQIIDLLANGIKNIHIYSMNKPNVAETIMSQLSEIVKC
>A0A537PIJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MVQQAQFHASRSAGVAGQCRIRVSFEFFPPKTEEMDKTLWESVQRLAPLAPSFVSVTYGA
GGSTRERTHATVKRILAETALVPAAHLTCVAAKCAEIDAVVRAYCEAGVGHIVALRGDPP
GGAGERYAPHPGGYANAAALVAGIRKIAAVEISVAAYPEKHPDSSTVEADLDMLQAKVDA
GADRAMTQFFFDNDHYFRYLDRVRARGIDIPIVPGILPVQNFKQAKTFAERCGASVPRWL
AERFDGLDDDPATRKLIAAAVVYAICHLLGLRPHAAPMVRKAVA
>A0A3D1G9B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneolaceae bacterium|TrEMBL
MKVTEYFKQAEGKTLFTIEVLPPLKGQNIQTLFDHIDPLMEFKPPFIDVTYHREEYVYKK
RTDGLLERKTVRKRPGTVGICAAIQNHYKVDAVPHIICGGFNKEETENALIDLNFLGIDN
VLVLQGDVRKPDRDFVPEPGGHTYASELLEQVVQMNQGIYLDDEIDNATSSDFCIGVAAY
PEKHVTAPNMETDLRHLKEKVDKGADYIVTQMFFDNQKFFDFVKRCREMGITIPIVPGLK
PITTKRQCTLLPQMFHIDLPEALSSELEKCKDNEAARQVGIEWAVQQSKELVEFGVPTLH
YYSMGKSKSVYEVAKEVF
>A0A2M9JEH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB01635|TrEMBL
MSTLRDILASGAPTFSFEFFPPRTAAGSRMLWQAIRRLEALSPTFVSVTYGAGGSSRDRT
VEVTKRIAAQTTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPNAPWT
PHPQGFTHAHELVRLVRNLGGFSVGVAAFPERHPRSADWHSDISHFVAKCRAGADYAITQ
MFFDVEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSNARFPAALADRLEAAA
GDPAEGHRIGVEYATSMAERLLAEGAPGLHYITLNRSTATLEIHENIQSIRTSRSTHALA
AAR
>A0A1Z8TFQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium TMED58|TrEMBL
MIKKKFIKTIEIIPSRYKIDNLFLNKVLKYSKSFDFIDLACAPMANLRISPISFAHNLIM
KGIDPQKIIINISVRDKNSLALQSDILGASGMKIKNLLLVKGDPISIGNSKKSKEVFELN
TNDLISLVAKLNKGRDYSNNKMDYKPGFAIGSTLNIDLPIEKIKRNLRNREKIGSNFFIT
QPLYSETDFVNLCELSSISSSKILAGIFPIKNIRTLNNLNNKINGINKDNPLFKTLKKAD
EKDFQKLSSSYLVDLLIKYKKDLDGVHIMTAGDLKVASKLSEKI
>A0A522CE26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MRLPFIMPQDSDLDVSFEFFPPKTAKMEETLWDSFNLLSQLQPKFISVTYGAGGSTRERT
HDIVTRIHKKTGLHVAAHLCCIGHTQDEIAEIVKGYWAEGVRHIVALRGDPPGNTGKYVP
TPGGYEYASDLVTGLKKLHPFEISVAGYPEGHPEAINAQLDLLNLKKKVDAGADRVITQF
FMNPEKFLHFRDRAAAAGITVPIVPGILPITNFSKTLDFAEKCGARIPKWMIQLFEGLDD
HPRTRELVAATVASEQCRVLHEEGVRNFHFYTLNRAELTLAICHMLGMRSKQVQQKAA
>A0A520W4S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MNNYFEKKLKSKEFVFTAETSPPDSTVRSDITDRILCLKDLADAINVTDGASAKSHLSSL
VVSSIMKDIEIEPIL
>A0A0L8V7C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sunxiuqinia dokdonensis|TrEMBL
MKVIDIINNSDKTVFSFELLPPLKGNDAGNIYRTIESLIDFDPKYINITTHRDEMVFKEL
PDGTIEKRTVRKRPGTVAIAAAIQHKYGIPVVPHILCGGFSKSETEHVLIDLNFMGISNV
LALRGDGLKTDNMFRPNPDGHANANQLVEQIVNLREGKYLEPDLKNNAPLDFCIGVAGYP
EKHFECPNFDTDMIYLKQKVDAGADYIVTQMFFNNEVYYNFVDKCRAAGITVPIIPGIKP
INLKNQLTVLPKIFSIDLPQELATELAKCKDDQEAKVVGTEWAIYQSKDLVAHNVPSLHM
YTYGVSDNARKIVKAVF
>A0A2R4N1H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carboxydocella thermautotrophica|TrEMBL
MSRLQQLLEAGRFVVTAEVGPPKGADASTIRHHAELLAPYVDALNVTDNQTAICRLSSIA
GAFHVQAAGVEGVVQMTVRDRNRIALQSDLLGAWSLGLKNVLCLSGDHQTFGNHPTAANV
YDIDSIQFIRGLQRLREGKFFNGEPLHGEPPQFFVGAVANPFADPFEYRVLRLEKKIRAG
ARFIQTQCIFDLERFDRFMQLVRQRGLHEQAFILAGVTPVKSVRMAEYMQKNVSGMIVPD
ALIQRLKQAENPKQEAVRVVVEQIQALRQIPGVRGVHIMAVAWEEVVPEIIIQSGLR
>A0A136IMI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microdochium bolleyi|TrEMBL
MHIREMVADAEKSGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDVTWGAGGRIA
ELTCDMVAQAQAYFGLETCMHLTCTDMGEEKVNDALAKAYKAGCTNILALRGDPPRATEK
WTATDDGFQYAKDLVAHIRKLYGNHFDIGVAGYPEGCDDNKDEDSLLDHLKEKIDLGGTF
IVTQMFYDGDNFIRWVRKVRERGITVPILPGIMPIATYASFLRRATHMNCKIPEEWMTAL
EPVKNDDVAVREVGKTLVAELCRKIMAAGIHHLHFYTMNLAQATRMVLEELDWMPTSTRP
TKKALPWKQSLGLGRREEDVRPAFWRNRNKSYVSRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKKWGEPQCIKDIAQLFVRYIEQDIDSLPWSESPLTSEADAIKDNLIK
LNQRGFLTINSQPAVSGVRSNHPVYGWGPPNGYVYQKAYLELLVPPYMFQDVVKRIESNP
DMSYYAVTQHGSLVTNAPSEGPNAVTWGVFPGKEIVQPTIVEGISFLAWKDEAFQLGMDW
AHCFDANTPSRVLVEEMMSEWHLVNIVNNNFHDQDSIFALFDGLAAKDLEAPPTPKLAKA
TTNGSLSNGAHDTNEAMAATA
>V6UA53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HCCB10043|TrEMBL
MALGTASTRTDHARTVRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGPWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A3D3WF61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTDTIDMIAKAGANWSIEVTPPGAAKIEDFSSILAEGTTVNVTFLPGTNPVDTIDVAKRL
RDSGLVPVPHIAARSLKSKDQLAELVADMTSRANIDEVLVIGGGVTQPVGEFASSMEVLE
TGILQSAGIRKIGVSGHPEGSPDIKDNLLADALAWKNEYARKEGLDLYIETQFCFDADAV
IAWEKRIRADGNTLPIRIGIPGPATIKTLFRFAQISGIGPSMRFIAKQARNVTKLLTVQS
PHLLIAGLAEAMANDPDTKLNHFHYYPFGGVAKTAVWASQVASGQVKLLPKGGFQVIEQA
ASKAS
>A0A3B9K1S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
CKALQDNGINEFHFYTLNRADLSYAICHILGLRINSR
>A0A534MI58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MRSGSRLERILASGAFAVTAEIAPPASADGAEIRENASRYRGAVDACNVTDCTRARVHIA
SLAAAAIAIQEGVEPVMQMVLRDRNRIALQADLLGAAALGVRNVLCLWGDPPSAGNERDA
KGVFDMKTEDMIEMFRNLRDAGTLRGGDKVKTPPKVFIGAAADPFRGSKEESFGKLRAKV
MAGADFVQTQGVYDVDAFEEWMRLVRKEWLHEKVYILAGVIPLKSAKMARFMVEKLGAVV
PTHIMDRMENAPNPRAEGLSIAVRTIKALKKVDGVRGVHLMPVGWDGVVPRLVKDAGLAP
RPETAV
>A0A534MH12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MPAEVASRAIRAGSRLERILASGAFGVTAEIAPPASADGSEIRRHAAVYRRTVDACNVTD
GQRALVRISSLAAATIALQEGVEPIMQMVSRDRNRIGLQSDLLGAAALGIHNVLCLWGDP
PPAGNEKDAKAVFDLSTEEMIATFRALRDTGILRGGDKVEQAPKVFIGAAADPFRGSKEE
SFGKLRGKVTAGADFVQTQGVYDVDAFEEWMRLVRKEWLHDKVYILAGVIPLKSAKMARF
MVEKLGAVVPKHILDRMDRAPNPKAEGVSIAVRTIKALKKIEGVRGVHIMPIGWEEIVPD
LVREAGLLPRPDPTP
>A0A6N7JW96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. MYb238|TrEMBL
MPRLASIITDGYSLEVSARAIPALAAVAPRIAPGTTVFIPYLPGEDNEARLGAAAAVRGL
GFEPMLHVPARRMASLAELDSFVTRAVAEAGAERCFVIAGDSSSPKGPFPDSASLIETGV
FERAGIKLLGVGGHPEGHPVMGEAARWEVLARKCRSIEGRGMTPLIVTQFGFDADIVLAW
LEALRGHGIEHPVRVGVPGPAGVAVLARYAAMCGVSASASIWSRYGISIGKLFGTAGPDL
FVDRLANRLTEAAGEVNLHFFPFGGIARSVEWIEHYRVRSH
>A0A7C2LN28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MKYYSEFMRSLKSSEFTISGEIDPPKDVNPDEVKEQVKHLKGTVVAANVTDNPIGDVIMN
TLAPCVIMQDLGLEAIYQQTCRDRNRIALQSDIIGATALGIKNVLALTGDHPKMGNHPQA
KPVFDLDSVQLTGMLRKMREGSTLAGTELENPPEFHIGVGISPGVEPLEPEIIKLEKKVK
AGAEFAQTQVIYDVKILERLKDEASHLDLPILPGFAPLKSIGMAKFMIKYVPGIRIPEET
MKKLEESKNRVETSIEIVAELIAAARDMNFSGVHIMPVGMDIHVREMVERAGEI
>A0A4Q1A354|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp. CECT 9299|TrEMBL
MFETLISKLQDGKYLTLETTPQHEPSMHNIVEKIKKFKIDSKVDGFTCTDNPLAKLKYNS
LFAALKLQTEFKKPVIATMTMRDRNKIALQSDLLGANDFDIRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFAVVNSYAKNFGSLEKKMNLKI
QNGAVGVITQPVFDIENVKKLLESFEIAKENVEGDKKKSQLILGLFPITKLRTALFLSAQ
VPGIHVPQFWIDELERAHSISEEEEYKVGMRLSKNLFKEINKIHPKIHLMTANNKFEVAS
EILD
>A0A534JN54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
AKRFAVTAEVVPPASPDPSGLMATARRLKGTADAFNVTDSPRAHVHMASWAGAVLVLRAG
LEPVMQMVTRDRNRIALQADVLGASALGVRNVMALSGDDAKAGNEPGATAIVDLDTEAFL
ETLRDLRDKGVLHGGDPVDPRPPIFIGATANPFGGPMEDSFVNLRGKAEAGADFVQTQAI
FDLDAFEEWMHLVRKEWIHEKLHILAGVVPLKSAKAARFMNEKVPGVVVPPDIMKRVEKA
ADAKSEGLAIAVEAVEALRKIEGVRGVHLMAVNWEDAVPAIVKRAGLLPRPDL
>A0A1B2M1Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter larvae|TrEMBL
MSRTVPISFEFFPTKTDVGAEKLRIVHQQLQSLQPEFFSVTYGAGGSTRERTLAAIQDFN
QKGSAVAPHLSCIGDHKIRIAELLDLYKAQGIDRVVALRGDLPSGQVGLGELPYAEHLVR
FIRQHSGDHFHIEVAAYPEMHPQAQSFDADIQNFVAKVQAGANAAITQFFFNPDAYFYFV
ERVQQAGIDIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQGYGDDSQSIRAFGHE
VVLKLCERLLAGGAPALHFYTMNQSQPTRQLVMDLGLSTPN
>A0A428ZWM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC 01325|TrEMBL
MPATDVRRIRRFAQLGSASFPADLAHRLEAARDDPAEGHRIGVAQATHMTNRLPTEGAPG
LHYITLGRSPATYGIHRNLGLTGRAV
>A0A1B9IZL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kwoniella mangroviensis CBS 10435|TrEMBL
MKITEKLQKAEKEGRTFWSFEFFPPRTAQGLQNLYDRIERMRNLGPEFIDITWGAGGKNA
DLTSSLVQVCQETIGIETCMHLCCTEMPKEKVEWALAQAKQHGCQNILALRGDPVAGTSK
WEPTPGGFTNAVDLVKHIHEHYPGDFCVAVAGFPQGHPETPEGMDGARQEIQWLKEKVDA
GAEFIFTQMFYDSSIFFDWVKRVREAGITVPIVPGIMPIQNWEKFEKWVQRESIVVPQHF
YDALRPVKGDDERVRQVGTKLVAGMCKEILANKEAGIKGLHIYTLNLEKGARMLLQELGL
EGRREQIAPLPWRPSLTPHRRSESIRPIFWANRVQSYLSRTDEWDEFPNGRWGDSRSPAY
GDLDGYPVSININANDAYNLWGHPTTFSEICDLFARFCRGDLAKLPWSSQPPASETSVID
EQLAKMNELGYLTINSQPAVDGVPSEDKVHGWGPTGGYVYQKAYLEFFVSPELLNPLIRR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWANLYSPGSPSRELIESTMNSSYLVNIVANDFRDGMSIFEPFLLDEHSTSKLGKVV
DGAQQTVNGVLDGLNGVVENVKSAAGVNGHSNGVAVNGH
>A0A0R2X9P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 6 bacterium BACL9 MAG-120820-bin42|TrEMBL
MKAGATALTLADNSLAILRVANTAAATLLREKFGTTSLIHLACRDKNLIGLQSELMGLAA
LGHRHVLALTGDPSKFGDHPGATSVYDVNSLGLIDLIRQLNEGRNSAGREVGKGAEFVIG
VAFSPNSKNFDAQVKKLERKMEKGAHFVMTQPVYELEMIRKMKDALGPLGIPVLVGVMPV
VSARNAEFLHHEVPGISIPDRVREKIRSLPEGPAQAEYGREVAAELAREVAQHFRGIYLI
TPMVRSGMTAPIVQEFLKTK
>A0A327R0K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenibacter echinorum|TrEMBL
MKVTEHIKKAEGKTLFSFEIIPPVKGRSIQELYDNIDPLMEFNPPFIDVTTSREEYVYID
RDGLLDKRLTRMRPGTVGICASIQHKYGVDTVPHVLCGGFTKEETEYVLVDCQYLGIQNV
MALRGDARKEEQYFNPTKGGHAYASELVKQIHALNHGNYLHDKVETVHSADFCIGVAGYP
EKHLEAPSLITDLKRLQEKVEAGADYVVTQMFFDNQKFFEFVEAAKKMGINVPIIPGIKP
IAVKRHLQLLPQVFKIDLPQDLIDAVDDCSTNADVRQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIEAIAKELF
>A0A430FM37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium goeldii|TrEMBL
MHKPIFSLEVFPPKRDAPIGTIYDALDGLEGLKPDFISVTYGHGTHADRTATARIANTIR
QDYQIPTVAHLTALYSDTERIDEALDLFEKAKVGGVLALRGDHLDGCEPVGVFNHASDLI
TYIRERKPDLKILAACYPEGHTESESLDEDIIHLKAKVDAGASHLISQLFYDNADFYRFL
EKARAAGITVPIEAGIMPVTSAKSVYSMASKNNTRIPKAVTAMLDKWGDDLPSLRAAGIN
FAAQQITNLVANDVDGIHLYTMNRAATARRIWHDVQPLFSNNLEQ
>A0A4Y8LEK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jeotgalibacillus sp. R-1-5s-1|TrEMBL
MTILDEMKNRILIGDGAMGTLLYSYGTDQCYEELNLSQAEHIQKIHRAYIDAGADIIQTN
TYGANYHKLERYGLEEQVREINTAAVRNAKKAAGKDTFVLGTSGGIRSFRPQSIELNEIK
RTFREQLYCLLLEGVDGLLFETYYDLEELSAVLDIARKETDLPLITQISVQEPGVMQNGT
SVAEALLRLEQAGADVVGLNCRQGPFHMLKSLEQVPLPERAYLSCYPNASLPSYTDGALQ
YSNNAAYFREIAPSFREQGVRLLGGCCGTTPEHIRSFSDALSGLEPVSEKIIAQPAEPII
VRDREKELPEPLTDIVNRRKSVIVELDPPKKLSTDSFMEGAKALSEAGADAVTLADNSLA
SPRVSNESLGYLIKQQGVRPLVHLTCRDRNLIGLQSHLMGLHTLGLHDILAVTGDPTKVG
DFPGAASVYDVSSFELIEMIAQLNKGMSMSGKDLGEKASFTIGAAFNPNVRSVERAVQRL
EKKIDAGADYFMSQPVFSEEKLIETAEAVKDLGKPVYIGLMPLTSSKNADFLHNEVPGIK
LTDQVRERMAAVSGDREKSHREGIAITKSLIDTALDLFNGIYLITPFMRYEITAELTRYA
NEQAAKRAGGNQYVTNKLH
>A4WUZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cereibacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)|TrEMBL
MARPRISFEFFPPQTLEASFRLWETAQMLAPLKPDFVSVTYGAGGTTRKLTHDAVETIHN
HYKLNVAAHLTCVDATKAETLEIANSYAEAGVTEIVALRGDAPKGAERFTPHPEGFANSV
ELVEALAATGKFKLHVGAYPEPHPDSADTLADVRWLKRKIEAGASSAITQFFFEADTFLR
FRDLCVKEGIRAPIIPGILPIENWSGVKKFAARCGAQVPGWLDEAFANAKRDDREELFSV
ALCTELCDRLLSEGVEDLHFYTLNRPTLTREVCHALGILPEVALQNVA
>A0A7T7C0X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia sp. cqz5-12|TrEMBL
MTSRLTIPDSSQLPPAERDGNVGRLERVLRSGQFAITAELAPPDSADPQEVHARAQLFAG
HVDAMNATDGSGANCHMSSVAMCALLAREGHETVMQISCRDRNRIAIQGDVLGAAALGIR
NLLCLTGDGVQVGDHPEAKPVFDLDSLSLLEIIAGLRDKHAFASGRSLTSAPQVFLGAAA
NPFAPPFAFRPHRLAKKIAAGAQFIQTQYCFDLPRFQDFMHRARDLGLLEKCFILPGVGP
LASARTAEWMRRHVPGVHIPDNVLKRLKGARDQKAEGRDLCIEMIQQLREIEGVSGVHIM
AHRQEALVPEIIQRAGILGARRPYTPQAPLGATPPIG
>A0A7H9LN68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J1QFH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Temnothorax curvispinosus|TrEMBL
MRNLILEKDTCERSDADTNDSKDNPSVHGFDTGNLRKTVVDLRQSLRDKINKNEIFCSFE
IVSTRKPGAFYRRLLIDMEEYSPLFYSLTWHNEAASSNDSYLPLDLVENFPPNTLLHLAA
KGLKRDEVVRILKKTLALGIVNIFALRGDSLSENGDFEHAADLVAFIREQFGDTFCVCVA
GYPQTHPESSSKELDLHHLKAKVEAGADFIITQICFESRLLIDFVRDCREIGIRVPILPE
ILAPASHACLEKMTDICGLDVPVEIKDDLARMKDDDRAARKYSVDLITRIITDVIRSGVT
RGFHLSTLNRLSLVAEICKRVKFLGAENS
>A0A7U4RQV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum lithotrophicum|TrEMBL
MFEKFCDILCGDKNFITVEVNPPHGASLDKILEDIKKYKLHEKVTGFSCTDNPLAKLKMS
GVLSAIKLQQTFKKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKFSDQPE
VKGVLERDSTLLLSIIYHLNNGVDYSNKPLNPAPKPIYPFAVSNSYARNMKSLQKRIVKK
LDYGARAIITQPVYDLENATELLELFEEAKTMSVRETAKEAHLILGQFPIVRARTANFID
DKVPGISVPKEIIDEMNLAAMDGEAKEQEVGFALSKRIFDAMMKKHGKVHLMTHNRFDLC
SELIGEV
>A0A5I0MCG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Durban|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7Y7M6Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nguyenibacter vanlangensis|TrEMBL
PGARAMVTTAVAAALCAQLRAAGVSQFHFYTLNRADASLALCRLLGRRGGES
>A0A376L3R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVSPGAKSAQADLLQPETQSRCRSQPR
DYSVLL
>N1PKU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dothistroma septosporum (strain NZE10 / CBS 128990)|TrEMBL
MHITHKLDAAHSKGQPTFSFEYFPPKTAQGVQNLYDRMDMMHGLGPAFIDVTWGAGGRHS
NLTVEMVKNAQAAYGLETCMHLTCTDMELTKVDGALKDAYDAGCTNILALRGDPPREQEK
WVETQGGFRYARDLIKYIKKTYGDHFDIGIAGYPEGPDPETSADEHIKYLKEKVDAGGTF
IVAQMCYDADIFIDWVKKCRAAGIPDSVAIIPGIMPISTHAAFIRRANWTQCRIPPHWHE
ALDPIKNDDGAVREVGCDLIVEFCRKLMDSGIMHLHFYTMNLSRAVEMVLEKLDLLPAAT
SPNPDLKPLPWRQSLGKNRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
SLDEYGIGLKGTNEHNRKLWGEPKTLKEIANLFVGYMRGKVETLPWSESPINEEANTLVD
DLVDLNSRGIFTINSQPAVDGAKSNHPVYGWGPQNGYVYQKQYLEVLVAPELIEEVIERV
NRDPDVTYYAVNCSGELKTNAPPDGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYH
LGLEWSKCYDDGSVSRSLVQDITQNWYLVNIVHNDFRQNNGIFDLFKGLAAPGFDANPGT
NGLSNGTPNGVNGHHDEPETNGSAPETNGVPDGNNVVNGADKAASNSPLKN
>A0A4U7KD05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium polonicum|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLRGIAQDYWQSGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTSVFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPEVTR
>A0A286AC79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas ureae|TrEMBL
MDSQKKFSPTFSFELFPPQTPQGIEKLRLTRQQLAQFNPKFFSVTFGAGGSTREPTFETV
LEIQSEKHVVAPHLSCIGSTQENIRIILEKYYEIGIRRIVALRGDLPSGMAQAGEFRYAS
ELVAFIRKEFGSSFHIEVAAYPEYHPQARSAQADFENFKRKIETGANSAITQYFYNTEAY
FHFVDSCESAGLSIPIVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLEGYSDDSASIQA
FGLDVVTDLCERLLKAGAPGLHFYTLNSANLTSIIWQRLNLKEYVQ
>A0A5F1DMM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPTGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1F2QMZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium RBG_16_70_10|TrEMBL
MTQPIYDPRTLERFFSMIRHLRVPLLVGILPLYSHRNAEFLHNEIPGMTIPDDIRERMKK
AGSGEKAQAEGVAIAREATLAARELGQGVYLMPPFNKVDLALRVIEVLH
>A0A2E1XS53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacteriaceae bacterium|TrEMBL
MTSPDTNPLDPSAPLDPLPGHVSRGRLERVLRRGEFAVTAELNPPDSADPQEVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDEQRFLSGRPITSPPHVFLGA
AINPFAPPYDFRPHRLAKKIAAGAQFVQSQYCYDVPMLREYMKRVVDMGLHEKCFILVGV
GPLASAKTAKWMRSNVPGVHIPDAVIKRLEGAEKQKREGKRLCIDIMNEVKEIEGVSGVH
VMAYRQEEFVAEIVHESGVLKGRKPWQRESRPDDAVIAERLEEIMAQEAERPAAIVADIV
DNN
>A0A6N7QNW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spiribacter sp. C176|TrEMBL
MTLAAPRYELIPIRGMLEEAERLPAGATITVTCSPKHGIERTLEASVELAKRGYVAIPHI
ASRLVRDESHLELILQTLAQHSLNEVFVVGGDAPAPVGVFNGAVPLLEAMAASPLRPARI
GVTGYPEGHAEISNDALEAALIAKRPYADYLVTQLCFDSAPILQWLTDIHQRGIGLPAWI
GLPGVMDPRRLLSISLKIGIGSSLRVLKRNQGITRQLWNGAYAPDHLIDPLLDALVEPGA
PPVCGFHLNTFNHVAPLLDWQANRLAETA
>A0A385EWK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii WM99c|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGK
ARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVKTGKEFTPEIARFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAKLLLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKQT
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A1Y3LKG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSRQATPKPLLACLMSLTHSRAAMLDHVAGVTVTPSMRDMLEAEAAQSK
VFALARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQTQVHTLEQWAPA
WRASWQMPGLPAVIFHPPQAAWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRRPLWATHLGAQVLHKVERAVKRPLVGCDTCGRCRLEDTLYVCPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVRQTAVLTERLIPCIEVESRHRSSWPQWFQAATP
RRLSPQPAPRSQPES
>A0A1X0ZV24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQLKTALHDKTFVCVMEFVPKSSSERFASIEALMARKHLCGWPMTVAIADRVGSPFEMS
PLDAYSSFRQPHPTLLHFSGKDRERHHLLDQLQQMDAAGLDQLLLLTGDRLPGHVPGQRP
VRYLESVSALQIVRQARPDWLLGAGMHPFKYREEEGGAQYFKAEKKLAAGADFLALQLGF
DASKHLEALRWMQRQPNPKPLMACVMGLTLGRAKIFEHVAGIVVTPSMHDLLAAEAAVSK
AHAQARSLERLALQIIGLRLMGYAGIHLSGIHDLAQLQALENAINDWQARLQSLEQWAPA
WHACWQMPGLPAVTFHPPGANWRLGESQVTASPKETARYHLLHGAHSLLFSRTNWLSQAF
GWAVQRPLWATPTGARVLHRLERSVKRPLLGCDTCGRCRLEDTLYICPESCPKGLANGPC
GGTTLNRCEFGDRECVHSVKYRTAKAVQQTAVLTERLIPCVEEGTRHRSSWPTWFEAPAA
APLCGSALAPRSGPQAEPKSPTQPASDRAGTLPPPQKQRCPL
>A0A1Q7P0A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon 13_1_40CM_2_39_13_2|TrEMBL
MTVTYELNPPKVIQDTVLSHQQLQESVNKLKTKALEVSKVCNSIHVTDSVLGIPRISPIT
IGVFIRNSNDGIELSASVRVRDRNLTSLTQTICDAILLDLNAVLILKGDPPPAGPKDSKL
VPSEVVKQFNEQGFGKKIDLFLSLPSNPNFEKIHKKIEAQPKGFVTQVISSFDQIIKIVD
KLKPQGFRIIPCILLPSEKNLQSAKRLNLDWSNYSNDVVGFIKDAHKISGNVLISSPNDF
KRALEILKKLT
>A0A7Y8D1Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKSALREKTFVCVMEFVPKPSAERFAAMEAIMARGHLCGWPMTVAIGDRVGSPLDLS
PLDALSSFSKPVPALPHFSGKDRERHDLLAQLKRMDAAGLDQLLLLTGDRLPGHQPGERP
VRYLESVAALQLARKACPHWLLGAALNPFKYREEEGGAQYFKAEKKLAAGADFLTLQLGF
DASKHQEAMQWMGRQAEPKPLLACLMSLSHGRAAMLEHVAGVTVSPSMRDMLEAEAGVSK
AYAQARSLDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEDWQARVHSQEQWATA
WAGSWQMPGLPAVTFHPPQADWRQGQSRVSATAREKLRYHLLHGFHALLFSRNNWLSKAF
GWAVRQPLWASDSGARWLHGLERSVKRPLLGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVQQTAVLTERLIPCIEVQTRHRSSWPLWFAAQTP
ARFSPQPTLRNPPESSPQAVHRQ
>A0A1B2F7J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQLKTALHDNTFVCIMEFVPKSSSERFASIEALMARQHLCGWPITMAIADRVGSPFEMS
PLDAYSSLEQPQPALLHFSGKDRERHHLLEQLQQMDAAGLDQLLLLTGDRLPGHVPGQRP
VRYLESIAALQTVRQARPDWLLGAGMHPFKYREEEGGAQYFKAEKKLAAGADFLALQLGY
DASKHLEAIQWMRRQPQPKPLTACVMGLTLGRAKLFEHVAGIVVTPSMHDVLAAEAAVSK
AHAQARSLERLALQIIGLRLMGYAGIHLSGIHDLEQLEALERALEHWQTRLHSLEQWAPA
WHACWQMPGLPAVTFHPPGANWRLGESQVTASPKETARYHLLHGLHSLLFSRRNPLSQAF
GWAVQRRLWNTPTGARVLHRLERSAKRPLVGCDTCGTCRLEDTLYICPETCPKGLANGPC
GGTTLNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIDADTRHRSSWPTWFQAPAA
TTTTAKPCGNGLAPQSATEAEPKAPALHTSKVPELDN
>A0A7L1PHL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oriolus oriolus|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A1U7J2X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phormidium tenue NIES-30|TrEMBL
MGYRLRTAAQADQFLVTAEVMPPKGGNPEHMLAMGQMLKGRVHAVNVTDGSRAVMRMSSW
AASLLLQQQGIEAVCQVACRDRNRIALQADLMGAHALGLRNILALTGDPVKAGDHPEARS
VFDLESVRLLKLLAKLNFGVDSHDKPLSDGALDLFAGAAIDPQSTSWSGLQRRFEAKVKA
GAQFFQSQLITDFDRLAKFMDQVASGYNRPVLAGIFLLKSAKNANFINRNVPGVNIPQTI
VDRLAAASDPLQEGVQIAAEQVQAARQVCQGVHLMAVRREDLIPQILDQGGVAPVDAALA
ER
>A0A385EYR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii WM99c|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A161HNG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sugiyamaella lignohabitans|TrEMBL
MKISQKLQKAHSSSHRPTYSFEFFVPKTSQGVQNLYDRMDRMYELGPQFIDITWNAGGRL
SNLTCEMVSTSQSIIGLETCMHLTCTGMPIQLVENALKDAYNSGCQNILALRGDPPHGSE
STSANGNELVPEFRYAKDLIKYIRAKYGDYFDIGVAGYPEGHPEESDIDVLIGYLKEKVD
AGATFIITQMFYDVDNFLSWVEKCRNAGITVPIIPGIMPISTYASFMRRATWCEINIPKN
FLDQLEPISGDDNLVREKGTELVADMCEKMVAAGIQHLHFYTMNLEKATVMVLDKLGILP
EYIPEEDKKNPPLPWRQSLALGREDETVRPIFWKNRKKSYVARTQDWDEFPNGRWGDSRS
PAYGELENYGVLLRHSAAKAIEIWGSPKTVEDLRDLFVGYLSGKIKSLPWSDAPISNEVD
SIKDQLLDINSRGFLTINSQPAVNGVKSTHPVHGWGPSNGYVYQKAYLELLVPPEVADKV
VHAVEKDPDVTYYCVDSRGNLRTNSPVDGPNAVTWGIYPGKEVIQPTIVEKISFLAWKDE
AFRLGAEWARCYDEDTESRRLVMGIVDKWYLINIVHNDFQDPDAIFRLFNNIH
>A0A0F6IGK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans str. FPW1039|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TAQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A6J4XJC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius sp. associated proteobacterium Delta 1|TrEMBL
MIRSITQKKSQAEIERLLKGLNRIFIIGCGTCTTLTRTGGEPEVRALKQDLSEKGKLITG
STVVPVACDNLTREFLGEFGEQIKQSDTLLITSCAFGVQTIARQLKKMVVPALDTLFIGK
ETAFGTFDEICTQCGTCIIGETGGICPVTNCHKGLVNGPCGGTNHGKCEIDVNKDCVWTL
IYNRLNELGRLESMKIYQKPRNHLGEPKPGKLKLE
>A0A5C3M4S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crucibulum laeve|TrEMBL
MKISQKIEQSTKDNKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPKEKVDIALRDAKQHGCRNVLALRGDPPMGKDE
WEAVDGGFVHGIDLVKHIRREYGDYFDIAVAGFPQHMLLPPEECDAEIRWLKEKIDAGVN
FIFTQMFYDVELFISWVKAIRAAGITIPIVPGIAPIQTWNGFQRATSLAKITIPQSFSEV
LEPVKNDDEKVRELGTKLVADMCRRILEEDIGIRGLHFYTMNLEKGTKMLLEELNLVPRV
ETIKPLPWRQSLTPNRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGHPQTFNDVASLFARFCTSDLKALPWSDQAPASETSVISKQLA
QMNELGFLTINSQPAVNGVRSDDKTFGWGPSNGYVYQKAYLEFFVSPGLLSLLLTHIERD
SNITYYVINRRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGQQ
WAKLYEPESTSRKLISEIMDTYFLVNVVHNDFHDPEAIFKPFLKAGTEYTAKSKSTAVNG
H
>N6UC90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium freirei PRF 81|TrEMBL
MSSNSENAQGGIRISFEFFPPKSEEAEQQLWNTVADLTEWDPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLAAGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVAALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRAAGIKIPIVPGIMPIQNLTQLKRFAGACGTNIPSWLDERFEGTDD
HAEERARVAAEVAAEQIEDLVRRGIHEFHLYTMNRSPLVSAVLERLGIQRKAEARAGAAA
>A0A348AK60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomusa anaerophila|TrEMBL
MLLKDKLGKSFVFTTELGGINGTDIEKSIAKVREYAGLDAINIHDCPNARLRMNSVMAAA
VINRATGMETIPHFTCRDRSLLGTQADLLGAHALGIRYLLPTTGDNPQHGPYKSSGVYDY
NSAELIALIKNFNAGQDANGQAFQGQTQFTVAATATPAAANLAAEIANMQKKVNADADFF
QTQPVYDAAQAGVFLAQAKVFGKPVLLGLMPLKSLKMADFVNKNVAGVTVPPTILAAMEQ
GKTGFEVACELISQVYRQVDGLHIFGMGDVAVTNRLVAYTKELLSR
>A0A419I8D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis panacis|TrEMBL
MTSVIERLQGDAPPFSIEFFPPRDEADEAVLWRSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLCPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPEGLTYAEELVELVRSLGDFCVGVSAFPYGHPRSADLETDTKYLVRKFRAGADFAIAQ
LFFEAEDFLRLRDRVAAAGCDALVLPGIMPLTTPRTLRTTIKLSGTRASQRLLDRLEPLS
DDPKAFRAAGLDAVTEMCEKLLAEGVPDLHFYTFNRAKATREVVTRLGLVPARA
>A0A120D2E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Magnetominusculus xianensis|TrEMBL
MMTAQNGVGSTRPSLSFEFFPPKKPEAEVLFWETLDTLMPYRPDFVSITCGAGGSRQAGS
GALVRQVRERTGLTTVAHLTCVGASRPTLTEMLNDYQECGIATILALRGDPPRNDPPGAL
EQGAFRYAEPFVAFIREYFPQFRIGVAAYPEGHPETADPSVDQLHFRRKVEAGADFAVTQ
FFFENDVYFRFVSDCRAKGVHIPIYPGIMPVTDFKQLKRLSELCGSTLPRWLTERFEAIR
DDPEKMRQAGVRVAVAQCRDLLRRGAPGLHFFTLNQCVVVPQILEELVGEFY
>A0A2G9XYC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium (Candidatus Stahlbacteria) CG23_combo_of_CG06-09_8_20_14_all_40_9|TrEMBL
MLDFRERIKKGVIIADGAMGTMLYSLGVPKGHCYDELNLSNPDIVKTVHRSYVAAGAELV
ETNTFGANRFILERYYNLGKKVRDINYRGAKIAREVAGDGIIIGGSVGPITRPYESAIKL
SKEERRDIFREQITPLLDGGVDIIIFETMAGVEEIKDAIFALQKLYGDFPFIAQFSFMDD
GKTLLGVDGVNAARELKGVEIMGANCGSGPKGIYSALKRMGCVTDAVLSAQPNAGYPGFV
YGRFLYPATPSYFAEYARRFVDIGVTIIGGCCGTTPEHIRAIKESVSEMKPKPRKIATIR
APVEKVSEEVEVVTQLKKKLQKGFVYTMEIDPPRGGIVERELAGARLFKKVGGDAINIAD
NPMAKLRMSALPLAYLIKRETGLECILHFTCRDRNILALQSELLGAAALGINNILALTGD
PPSVGDYPFAVAVFEITAKELVETIGSINHGYDRLGNPLAGRTNLFVGIASPIRNVDPDR
IWEKINLGAGFIQTQPVFDIELLRKFISFNFGIPVIAGLLPLHSIRQAEYFANEVPGMYI
PEEIIERMKNGESGICIAKELLKEIRKTYQGVCIMPQGRYEIVKELMGEEVSI
>A0A7G8JA23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. SYN20|TrEMBL
MSSALQSSLEAGTVTITAEVMPPRGGDPSHALEMARGLKGHVHAVNVTDGSRAVMRMSSL
ALARLLLDEGIEPVLQMACRDRNRIAIQADLLGAHALGIRNLLCLTGDPVRAGDQSKARP
VNELESVRLLQQVTAFNRGDDPVKGQLADGPTNIFAGAAADPQCASWSGLVRRMQRKKAA
GARFIQTQMVMDAAVLERFCREIAEPMQLPVLAGVFLLKSARNASFINRMVPGACIPENL
IARLEAAADPAAEGIQIAAEQVQQYLGVAQGVHLMAIKAEERIPAILKQAGVSLPG
>A0A741MXE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. arizonae serovar 41:z4,z23:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8D2N2G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zonotrichia albicollis|TrEMBL
MVNESQQSCSGSSSSRSDGGSSSGSEGSKDSSRCSTPVLDAERHERLRDKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDHMGAGGPLFIDVTWHPAGDPGSDKETSSMIIAYTAVN
YCGLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVYAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVRALLKVLRKYELRVNY
HIVNVKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLNSPTQQ
>A0A077NJ90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus bovienii str. puntauvense|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPSTTTMEQTLWKSIERLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKDKTGLDAAPHLTCIDANREELRNIAHDYWESGIRHIVALRGD
LPDSSGKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A1F8VV01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Curvibacter sp. GWA2_63_95|TrEMBL
MFANDRIPLSLEFFPPKTPEGAEKLRGVRQQLYALQPEFCSVTFGAGGSTQEGTFGAVRE
ILAEGVSAASHFSCIGATKDTVRAQLATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDL
VAFIRAETGDDFHIEVAAYPEVHPQAKSPASDLQAFSAKVKAGANSAITQYFYNSDAYFR
FVEEVDALGLEVPVVPGIMPITSSTQLMRFSDASGAEIPRWIRLRLQSYGDDVASIKAFG
LEVVTDLCEQLRAGGAPALHFYTMNQSAATLALCQNLGLSAS
>A0A1E4ME37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. SCN 66-18|TrEMBL
MATPLIHPNWDKAPDGITDGFSLEMTAKDEASLRDAAPLIPAETPIAVTFLPGEHVAARV
AATVAVRQLGFEPMPHFSARRILSEDDFEGYLKAVVEQAGVARCFIVAGDPPEPQGPYFD
TSALIATGAFERAGIKAIGVGGHPEGHPNMTVAECWAVLEKKVAEIERRGMAPLIVTQFG
FDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLSFAARCGVGASTSVLKKYGISVTN
LLGSAGPDKLVNAFAEGLGPEHGRVRLHFYPFGGLVKTLEWIHDYNRKHGI
>B1Y645|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6)|TrEMBL
MTTTPSLPLSLEFFPPKTPEGVTKLAAARQALYALQPQFCSVTYGAGGSTQDGTLATVQA
ILDEGWQGASHFTCIGATRESVRERLAQFKAMGMRRIVALRGDLPSGYGAFGEFRYASDL
VAFIRAETGDHFHIEVAAYPEMHPQARSPQADLQAYAAKVQAGADSAITQFFFNADAYWR
FVDDAQALGARIPVVPGIMPITNSSGIIRFADGSGAEIPRWIRLRLQSYGDDSASIKAFG
LDVVTDLCERLRAGGVPALHFYTMNSSAAVLQICERLGL
>A0A3D1PD90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium UBA11049|TrEMBL
MYNKTLLTSFRTAVKAGEFLVTAEVAPPKGSDASHTIAMAQTLKGRVHAVNITDGSRAVL
RMCPLVVSAILLQHGIEPVCQVACRDRNRIGLQADLMGAHALGIRNVLALTGDPVKAGDH
VDAKSVFDLESVRLLKLIRKMNEGFDGNDQPLTDGATDLFVGAAIDPQSPSWSGLQSRFE
RKLEAGAQFFQSQLITDFERLEKFMDQIASGSNKPILAGIFLLKSAKNAQFINRCVPGVN
IPQHIIDRLAQAKDPLEEGVHIAAEQVQIARQLCHGVHMMSVKREDLIAPILDLAGIPPL
VKS
>A0A0Q5GJI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. Leaf130|TrEMBL
MSHASACFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDMAPLEASKS
YPDTIDKVLHFSGKARDIQDFEHFLQQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHAYSQQILACVMPLTLGRANFMVKHKVAGIVITAHMLKVLADEKLAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLKLEALEELWNSLWQVT
TGKEFAPEIAHFSRQPTSKQLIKYRQLHVMHEALFESKIAKGVGRFIFKASFWENALVAK
VLIKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSIKARLAKALEQTEILKEKLIPTVAIETRGTSSWKNWYLATEA
>A0A1V5UVJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium ADurb.Bin242|TrEMBL
MSNPLRERLQNKTVIFDGAIGTELYKKNYFLNTSYESLCLSAPKAVREIHESYRDAGAEV
LTTNSFGANADLLNKFLLGDKTAEINRAAVTLAREVAGNELLVAASIGPAGELPGVDPES
VRKTAALLQQQAEALISGGPDFLLFESMRGAGDLEAVLLCMKELPDVPYVVSFAVDREAN
SKTGDTPARLLTLLDGAVRKPEAFGLNCGIGPESMLNALEILLKQCHYPVIARPNAGMPK
SVDNRSFYMCSPEYFTTYAMRFVALGVQGVGGCCGTGPDHIRDMARSISPLSRSRKAAEK
IFVKEEAVPEQQPVPLAERSALGAKLAAGKWIQSIEIVPPQGYELESTIEKARLGKEAGF
DAVNLPDGPRASSRVSSLVTAGQILSEAGIEPVLHFCCRDRNLIGMQADLLGCAAMGIHN
LLFITGDPPKLGDYPFASGVFDMDSIGTVRLQGRLNRGIDIAGKSIGRPTAAVIGAGADP
NAIDMEREIRRTREKIDAGAEFFITQPVFDVEPLLRFIDAVPGLSGLPVIAGIWPLAGYR
NAEFMRNEVPGVVVPDSIMERMARGTTKEEQRAEGIRIAREAVAAIRHKVAGIQVSAPFG
NVKTAIAVIAPE
>A0A2S5BIP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodotorula taiwanensis|TrEMBL
MTSTPELRSTFVSQKVTDKIAALPDDRPYYTFECFPPKTESGLVNLIDRIDRMSALNPLW
MHVTWGAGGSTQERSLELAGASQGMGLETCLHLTCTNLEQGVLEKTLDRAKKAGILNLLA
LRGDPPRGEEYWTASSDDFQHATDLVRFVREKYGDAFCIGVAGYPEGHADSPDKQADVDY
LFEKQEAGADFVITQLFYDVDVFMQWYRRCRERGITIPIIPGIMPIQNYLSFRRMTNLCG
TQIPPEILADLERIQHDDAAVKTYGVELAVKMMRQLYENGIRGFHLCTLNLEKSVTRVLE
ALEWVEPAEARTRTSRQRTLPTNGGPLPKVVNSLRPAPAAGASVAGPDISRKDSPASWDE
FPNGRFGDARSPAYGEMDGYGVSLKLPPGEALRQWGQPTQLADVSRVFSSYLRGELPSNP
WSEEPLRAETDMIAAHLIEMNDKRHWWTVGSQPAVDGAPSADAVHGFGPKGGYVYQKAFV
EFFLTKEELDELERVAAREEAERREKGDGDDGLVKWYAGNRAGDFRSNMGQGDVNAVTWG
VFGAKEIVTTTLIEEMSFRAWCEEAFALWNEWSLLYPAKSDSRTFLRSISDSRWLVSVVH
HDYKDKDALWRWLMQLQIAGREGGEAEGR
>A0A2S1H5E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. 2017|TrEMBL
MGLLEELKTRVLTADGAIGTLLYSYGLDYCHEEMNIIRPEIVEKIHGEYIAAGADIIQTN
TYGANAIKLARYGYEGRVAEFNSAALEIAKRAATPGGQFVLATIGGIRGVRKSEATLEEI
LAAFREQAETLLAGAPDGFLLETYYDFEEISHCVNLLRTLTDLPIIAQVTMQEPGVLQNG
MSLNEALQDLERLGADIVGSNCRLGPFHTIQAFETVNLPKTAYLSAYPNASLLDVEDGRV
VYESETDYFARAAVELVNQGVRLIGGCCGTTPKHIAAVKQRLVNIVPIETKELKPGRTEF
VRVAEPRKQEPLHVKAKRERSVIVELDTPRHLEIEGFVEGAKKLASAGADVIMMADNSLA
SPRISNIAMAAILKEHGIRSLPHLTCRDRNLIGLQSHLMGLNALELHDILVVTGDPTKVG
DFPGATSVYDVSSMELITLVKQLNEGGSFTGKTLRKQANFSVAAAFNPNVRVLDRAVARL
EKKIEHGADYFISQPVYSKEKIVEIYEATKHLETPIYIGIMPLTSSRSAEFLHHEVPGIK
LSDEVLARMAACGEDKEVATKEGIKIAKELLDTACQYFNGIYLITPFLRYDMTLELMDYV
NQFDANNKGVQSNA
>A0A8B9CMG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anser brachyrhynchus|TrEMBL
MTSADACGASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDRWF
SLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYC
GLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVK
HIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFLKFM
KDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVE
DVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKM
WGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGIL
TINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNYHI
VNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYE
EESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPAQQ
>A0A8I2EYE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MPLQYSFEITPNIDQVNLDGLLKLHPEFISITDRNHDMDNLLQSIRIADYIHANSSVDVV
IHLTGIDKNEKGVQEMLDLMQQHDIDSVLALRGDKLSQNDTAVTFPHADRLVEFIKQQYP
HVNISGTCYLNSSDEEMKWLRQKIEKGCTNLISQFSFDANDYIDYLNQIEIETPIWFGIM
PVISRSQAEKMLSLTHSTAPDELSVLMNQHDDDGVQYTAGMINKIKQAGANHIHLYSLNN
AENTKKIINKI
>A0A1E4I9A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. SCN 72-86|TrEMBL
MPGKVLVCDGAMGTMLHAAGVALGQPLSALNTGRPSLVRDLHTAYLSAGANLIQTNTFDA
NRLKLADIGQGERVAEVNIAGARLAREAAQACGRSAFVAGSVGPVRGTARHRVARDDQAE
MLREQIVALADWVDLLVLETFGEISAMAQAIEIALEACDLPIVAELTFERDGRTPRGEEP
AEVAVALASYEVAAIGANCTVGPAVLQGVVAQMAGAVDLPIVVQPNAGAPQRLGDELRYA
HNTKYFAGAAAELVAKGAAIVGGCCGTTPSHIRAITAAVRGLSPIREDRRAGARPSPARP
YRPRESIASAPQVRWPTGDTPVIIAGLPLSRGPEVAEYVDAARAAAVAGAGLVAVIDADR
QAPTVNPVSAAVLLNQRVGVDVLHQVEGAGRSMAALQADLLGAHAFGLRTVICRTGEVLQ
AGDYPQVASADEVDSTRLVGILAGLNDGVDWRGVPLPERTSFVIGALIDVTTADLNREVE
KVAVKVETGAHFLLSDVVYEESGARNVLSALRLRGVEVPVLFALAPFHDAQIIARLTHEA
PGARTSQTLGTTPPRDVVASALGLASALLADGAAGILVHGPASVDDRMTSIIKGLRDLCQ
GVK
>A0A0P7JZL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MPLQYSFEITPNIDQANLDGLLKLNPEFISITDRNHDMDNLLQSIQIADYIHANSSVDVV
IHLTGIDKDEKRVQEMIDLMQQHDIHSVLAIRGDKLSQNDTAVTFTHADRLVEFIKQQYP
HVNIVGTCYLNSSDEEMKWLRQKIEKGCTNLISQFSFNANDYVDYLNQIEIDTPIWFGIM
PVIAKSQVQKMLNMTHSTAPDELNVLMNQHDDEFGEDGVQYTAGMINKIRQAGANHIHLY
SLNNAENTEKIINKI
>A0A4Q7PPJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cuneatibacter caecimuris|TrEMBL
MKIRDLLKEKEITLSFEVFPPKTADKYEAVAQATEGIASLKPDFMSVTYGAGGGTSAHTV
SLAADLKQNYGVETMCHLTCVASGKAQVRSQLEKMKEAGLENVLALRGDIPAEGSFPDAG
HYHYASELIAEIREFGDFSIGGACYPEGHVESANKKEDLLHLKEKVDAGCDFLTTQMFFD
NDILYNFLYRVREIGVTVPVLPGIMPVTNAKQMKRICSLSGTYLPARFKAIVDRFGDDPA
AMKQAGIAYATEQIIDLLANNVNHIHVYSMNKPEVAGQILENLSAILGR
>A0A1G0M3P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium GWC2_58_44|TrEMBL
MKIVDKIANGEQFLSLEFFPPKEKSEWPAFFKTAGRLSQLNPLFASVTYGAGGSTKGDTL
EIVTRLKKEHGLETMAHLTCYGSYRGELQQFLDNLAQAEVDNVLALRGDPPLDAPPEFSA
CRTLLHASDLVSFIKESHPGMGIGVAGYPEIHPEALDPESDLAYLKLKLDQGGDFVITQL
FFDNSHYFDFVLRARAAGVDKPIIPGIIPVVSLKVIRRIASMCGAKLPSDYLAELEEADR
SGGAAAVQQLGVAYARRQAQELLAAGVPGVHIYTLNRDQAVLDLVEGLLPS
>A0A173H967|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. JY-Q|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0C3AFU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MRKQSFSVEIEANPGDLRQMKHYLHKWQPDFVSISNLSRYSYEEMVQCARYIQTDLNIPV
VIHLTGLTHTKEQIKNDFNELMDLNIRNFLLVRGNIHHNMRIENDFNYASDLIKYVNQLD
TDSKINVVAGCYPDIHVLADSLTEDIEYLKQKVNSGVDSLISLMCFDNKRIYKFLDKSRE
FGINVPIRIGIMPITDPFKRHYLAHNDVKMPEFSEEEDNLLENGINYAVNQINDLYEHNV
NGIHLYTHNDWMVSDRVFENIKQNL
>A0A1F9QFG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium GWA2_64_40|TrEMBL
MKVTERLRTGEKVYSFEFYPPKTAEDTAKLFNTALELKALSPDFVSVTNSSSGVMPYRTV
ALCGVLKSQFGLEVVAHLTCLAHTRAEIAEICSGLRKMDILNVLALRGDPHNVADGALRR
DYSYASQLTADLVKDGGFDVGGACYPEKHPESPSPEADIARLKEKADAGAGYLITQLFFD
NDFYFRFLDRAAAAGINLPVLPGLMPLTGYRQMQNFTQMMKVTIPARLRAGIERWEGDKD
GMFKFSVEYASKQAEGLLKGGAPGLHLYTLNRSRAAMAIFKNLKGAARP
>A0A3G6YUR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter nosocomialis|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPSIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A2S5B9F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodotorula taiwanensis|TrEMBL
MVKISDKIRKAEREGRPWWSFEFFPPKTSEGWVNLYDRIERMTQLGPIFVDITWGAGGST
SEATTNFVKTAHSDLGLETCMHLTCTNMPVEMVDKALKEAYDSGCRNILALRGDPPRGVK
EWKPTEGGFNHAIDLVRHIRKHYGDYFCIGVRLILELLWSRRVAGFPEGHPDSESQDAEI
RHFKQKVDAGADIVFTQMFYDADVFIDWGRRLRAAGITIPIVPGIMPIQTFSAFKRRTDF
AGTIVPQELWDLLEPIKDDDAKVREAGTQYVADMCRKILAADLGIHGIHCYTMNLSRGTE
MLLEEMQFVPTADRVKPLPWRVSLTQKRRTETTRPIFWSNRQRSYLVRTRDWDEFPNGRW
GDASSPAFGDVDALLAALPIKPQDAIDLWGKPVTLGDVAALFARFCRGELKRLPWSDQPA
AKETSRIAEQLAKVNELGFLTINSQPRVDGAKSEDPAFGWGPINGYVYQKVWVAYLEFFC
PPQHVEELLEILNDNPSITYHAVNKQGDFRSNTVPGPNAVTWGVFPGAEVIQPTVVDSAA
FQAWKDEAYELGSQWAQLYQETSPETQKLIHNVFDDYHLVNIVYNDYRDSDEDAVFKPFF
ELAGKKGLAAVNGH
>A0A2W5F9I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella oneidensis|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETNLVAAPHLTLVDASDEELLDLAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPSWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPKAV
>A0A0N0UV24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MSLKDTFKKKTVFSLEVYPPKTPEGTKKLVNALTGIKRIKPDFISITLGAGGSQNNNALE
LSSMIQNDLNIPAMAHIPGIYRSKKDVADFLKQLKQHNINNVLALRGDINPDETPVGDFN
HASELAEFIKTQGDFDITGACYPQKHPESVDLVDDTLHLKEKVDNGVGHLITQMVFDNQA
FYDFRQRLKLAGINVPVEVGIMPCTNCNQIKHITELSGLEMPRKFVDIMNKYANNKEAMR
DAGIAYAVDQIVDLVANGVDGIHLYTMNNTYVAKKIWEATHSLFEATSYQLQHPSLSGSD
NQ
>A0A838V4E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIDEIIATRKPTFSVEFFPPKTAEATEQLYTTAKALEYLEPDFVSVTYGAGGGTRDGTV
EITRALKDDFGFETMAHLSCVGETTEGLAETLDRIAAAGIENVFALRGDPPGNEGPFVRT
DGGLGSAAELAAFIAAGWNFSLGGACFPEVHPEAPDLETDLAYLKTKVESGAGFLITQLF
FDNQVYFDFVRAARSRGIEVPILAGVIPVASFAQTKRICSLCDATIPAPLEAAFEAAGGD
PEREFELGVAFAAQQCAELLIAGAPGIHFYALNRAPATRAVLGALRASRPWERTRGDAGT
LAGSGDELGH
>D3TQ40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glossina morsitans morsitans|TrEMBL
MSSNITNTTHLGAHFLPKIAAAPLETAKCSYEPKFRFNEQQLRKYPKTQQLKIAVAEKIE
KKEYFYGIEILARSHNPKLMLDYTKFGKMLPLFTSLVWLGLDYSRVANVEKVESVRVAKK
LKDNQREMLIAPHLSCYGLDTKRLKEFTELNFTNIVIVRGDQYDDEQEFKYASQLVAQMR
RECQDSITIAVAGHPEGHPSISTMQEDMKFLIEKINGGADLIITQVCFKAQALIDFIKSC
RLHSINIPIILGIYVPDNIKSLQFLMELTKIEMREEDLQQYRYYASKGTDEFRFFAAQKV
TEMILTVLKTKDINIYGIHFFTMNKFGMVTKVLEELRKYIKI
>A0A7V9TB84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MHVRHQIGVMSRVASSFLIPDNHIGRATVSSIAVAHEVALMGGRSIACLNARDRNLLGFR
RDLLTAAAYGVDEFLFVYGDRPETGTRSDDLTVRSMIEEARRFAADSELASKPLRLGVTS
RLAPLPSWKRQADFLFVQVSFSVEALLGWRAEISFDGPVFAGVMAPASATMARKLSADVP
ELAVPNALVEALDADRNAGVDFACQMVRDVRESGAFDGVHLIPVSRYPEIAARLERM
>A0A4Y9LZY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. TF02A_35|TrEMBL
MNRALTVRDPGTRASLRRTFETLGYEVIPFKKTQEQVLQHVPTDVRLTVTASPAKGQDAT
IDLTVALTGHGYKVAPHLSAQQIRDRAHLADVVARCREAGITDVFVIGGDPTETPTEFKD
AHALLVALHELDHGFTDIGIGGHPEGHPAVSEDVLFQALKDKAALAHHITTQIVFDPAVI
LRWARELKRRGIDLPVHVGVPGAVSRQKLLRVSGGLGIGESAKFLKKQQTLLWRFFVPGG
YDPTKIIKGLAPHLGKPDNALAGFHVFTFNDLEPTEEWRTRTLRSLA
>A0A0F2NVH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium BRH_c0|TrEMBL
MPTPKISFEFFPPKTPEGRVKLLAARDQLAALKPEYFSVTYGAGGSTRDNTRDIVMQIHR
DGYAVAPHLSFGGDSEQAVLELIQSYKDAGIRHIVALRGDMPSGMGIHKLVNANELVALV
RAHFGDHFQIKVAAYPEIHPDAESYQKDVYWLGEKFRAGADCAITQYFYNADAYFYFMEQ
CAQAGIDKPVIPGIMPITNFQNLVRFSDACGADIPRWLRQKMNGFGADSDGLKAFGEEVV
SRLCEKLRAGGAPGFHFYTMNQAEPTLGILTNLGIQ
>A0A1V3C931|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis sinuspersici|TrEMBL
MAPRNPAPRPRHIRELLDAGEPMFSFEFFPPRTPRAQERLWRAIREIEALGPSFVSVTYG
AGGSTRGMTVETTERIATDTTLLPVAHMTLVDHSVAELRHLVGRLADAGVSNMLAVRGDP
PGDPNGEWVTHPEGLTYAEELVRLIKDSGDFCVGVAAFPFKHPRSADVETDTDYFVRKCE
AGADYAITQMFFDPEDYLRLRDRVAARGCEVPIIPEVFPVVRTSFIPRSEQLSGAPFPRD
LAERFESFGDDAEAVRAFGIEYAQRMCERLLAEGAPGIHFITSNQSTATRQIYREIAGHR
SRPEAAGRP
>A0A2S5MWI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp|TrEMBL
MVEGKERKSRLLGAGEIAVSFEFFPPKTEKMEEQLWTAINRLAPLAPEFVSVTYGAGGTT
RERTHATVERIVKETALRPAAHLTCVDATREEVNAVAQAYWNAGVRHIVALRGDPASGAG
QKYEPHPGGYVNAAELVAGLKKIANFEISVAGYPEKHPESQTLQADMDNLKAKVDAGADR
IITQFGFDNAHYLRFLERARAAGIWVPITPGIVPIHNFRQVAGFAVRAGATVPAWLARRF
EGLDNDPETTKMVASAVATEQVMQLVDEGIKSFHFYSLNRPDLVYAICHLLGLRPLHTAP
LEDRRIMIA
>A0A1Z9HA25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaera sp. TMED151|TrEMBL
MSRIDQMFSERGPTASFEFFPPKDGEAWDALFSGISAFEQLQPSFVSVTYGAGGSTRART
HDLVVRLRSETSLLPMPHLTGRGHTKAEMESILVRFAESGVDNILALRGDPPKDGDPGPG
DFPHAIDLVRFIKSFNESGGHPNGGFGIGIAGYPEGHHETPNLLTEMDHFRAKVDAGADF
VISQLFFDNRRFLDWRDRCTMAGIQIPLVAGLMPITSAGGMRRMAELAAGTLIPARLLRG
VLDREADPEMVEAFGVLWATEQSRDLLDHGVAGLHYYTLNRSRAARRVYETLGIRDSRSF
MTGS
>A0A4P6MHA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassococcus sp. S3|TrEMBL
MPEVSFEFFPPQNLEASFRLWDTVQTLAPLGPRFVSVTYGAGGTTRDLTREAVATLHKSS
GLKVAAHLTCVNATRSETLAIADDFAKAGVTDIVALRGDPPKGTGAFQPHPEGFSDACEL
ITALAETGQFTIRVGAYPDIHPEAANPQADIDWLKAKIDAGAHEALTQFFFEADTFFRFR
DACAKAGIDAPITPGILPIENWKGARRFAERCGARIPDWTLSAFETAERDGRTDLLATAI
CTELCSDLIEGGVENLHFYTLNRPELTRDVCHALGIVPQVQLENVA
>A0A7X7Q8F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium sp|TrEMBL
MLASMPLTKPSTVGELLERARGPLFSFEFFPPRTEEEEPVLLRAVEALAPLGPDFVSVTY
GATGSRRDRTIHATRKIAAIGNPMTVGHLTCVAQSKADIAAALHEYADAGVTNILAIRGD
MPGGGEWEPHPDGLRNATELVEFVKNEGDFCVGVAAFVQPHPDSNDPDVDARILLGKVEA
GAEFAITQLFFETQDYFDLVERVRGMGCDVPIIAGLMPLTVITQIERFQDLSGQPLPASF
VDRLRAADPADVRSIGLQHTIDMCKDLIAGGAPGLQFFTQNRSKATREVLAAVLEDPGLA
IARSA
>A0A2P6U1V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorella sorokiniana|TrEMBL
MARIIDKLNAKIDAGELFFSFEYFPPKTDEGVANLKERQTRMAALGPTFCDITWGAGGST
ADVTLDVARAMQQEVGVETMMHLTCTNMPVDKLKDALTKAKEYGICNILALRGDPPKGQD
HFEQVEGGFACALDLVKYIRAEHGDYFGIGVSGYPEAHPDVIVEDGEQMHKNYWADIEYL
KKKIDAGADFVVTQLFYDVDRYQQFVKDCRSVGISCPILPGVMPIMTYGGFKRMTSFCKT
AVPQHVADTLEAIKDNEAAVKAYGISLGTMMCQRLLAGGAPGLHMYTLNLERSAVAILEN
VGLVPKKEAAKADRQLAKSP
>A0A7W9Y2N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium wenxiniae|TrEMBL
MNETTTRPRFDISFEFFPPKSEEMEAQLFETVDRLALFQPEFVTVTYGAGGSTKEPTLSA
VTGIIDKTSLPTAAHLTCVDASKDEVRAVVEEYRAAGVRRIVALRGDPTAGIGTTYLPHG
EGFQRTADLVQALAEYGDFDISVSAYPEKHPESRNMAADISVLKQKADAGAHRALTQFFF
DNDVFFRYMDEVAAAGVSIPVIPGIMPIQNLTQLKRFSKRCGATIPGFLDDRFEGLDDKP
DDRAKVAAEVSAEQIEELGRNGFNHIHLYTMNRSPLVSAVLDNIGYKPGMRKAAA
>A0A4R2R8F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tumebacillus sp. BK434|TrEMBL
MSSRHELFRQKLGSDVLIGDGAMATWLYQQGHAAGSSTEELCLKNQEWVREAHMAYLHAG
AQVIETNSYAANREALARYGLERKTTRINRAAVQIARQAVELAEAEAFVVGSIGSIAAAR
VMTANVEEFRDTFEEQAVALLHEGVDGLVLETFFDLEELLLALDVVRPLVASSGVPIIAQ
CSLLDVERTRDGYLLSDAYHKLQEAGADMVGLNCRLGPAEILRALERAVVPEGLGLSAFP
NAGRPAIVDGEFAYKPNYQYFGDSAVKLWEQGVSLIGGCCGTTPEHIQAIAGAVSGMKRL
PRVNPENAPRIEVFEREVVRFQQSEMPTIIDLVEKRHTVIVEFDSPRDLDVERYVEGSHE
LYKAGADAITIADNSLATTRMSNMALGSIIKRELGIEPVVHVACRDRNLIGQQSHLMGLH
ALGINQILVITGDPARVGDLPGASTVFDMSSFDLIRMVKQLNQGVAFSGRPMKNQARFVC
GAAFNPHVRNLEAAVARLERKVEAGADYIMTQPVYDLETMLAIKEATAHIKVPIFIGIMP
LTSTRNAEFLHNEVPGIKISQKSRERIKRFEGAAARAEGVEMCKELLDEAVKHYNGIYLI
TPFNYFEMTVELTKHVRAITQVTGRASTF
>A0A7S8D8J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium culmorum|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WEAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELHWAPSADRP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKAIQDIAELFVSYLNNKIESLPWSESPLTTEADEIRDDLIE
LNKRGLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPV
ANGAVDTEPIANGTAVTAAAN
>A0A7K7F1B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chionis minor|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFEDYFDICVAGYPKGHPEAESYEADLRHLKEKVIAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A667WB81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myripristis murdjan|TrEMBL
LVNSSHNGEPGKSDSSGASNSGGESSKESSRCSTPVLDADRSDRLRDKMLRRMESGDRWF
SLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVK
HIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRAETFLKFV
RDCRKIGIMCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIE
QAVEMCRLLLESGEVPGLHFYTLNREVATIEVLRQLGMWIEDPRRPLPWAMSAHPKRKVE
DVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKM
WGEELTSEDSVFEVFTCYITAQPNHSGHKVMCLPWNDEPLAPETNLLKDELEKVNRRGVL
TINSQPNINGKPSSDPLVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHI
VNVQGHNLTNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYE
DESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDMPPELVTDGAVSE
>A0A0Q7C0T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root1257|TrEMBL
MANTQAPRIGDLVRAGERSFSFEFFPPKDEAGEEQLWQAIRELEPYRPTFVSVTYGAGGS
TRDTTVRITGRIAAETSMTAMGHLTCVGHTREELEGVLDSYAEVGIGNVLVLRGDPQEGP
QAPWTPTDGGFTYAQELVELARGRGDFSVGVAAFPERHPASETLDQDADVLVAKARAGAE
FAITQMFFRAEDYFALVERVRARGVDLPILPGIMPILNLGNIRRQGEMIGTEVPASVVER
ISAHEGDPAAMRAAGIALAAELCEELLDGGAPGLHFYTLNRSKATREIFSALNMSV
>A0A2N8MJ09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. BJA-103|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDTADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPNGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTLRTLHTSIKLSGAPAPRRLLDRLEPLA
DDPKSFRAAGIDAVTELCERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A177GD93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter malorum|TrEMBL
MSLSRLSVELIPRSEDALAQDVASVKTLFPAADTLNIPDLMRFPLRSWDAAALTMPQFGT
VVPHVRAIDIAPGAPLPGSNVPGLKEVLVVHGDPPADLAHRTYPNSTESIIRRYRKEAPH
LRIYAAFDPYRRAPWRELEDIARKKDAGAEGFFTQPVFDLKLFDLCREWLQDEQVFWGLS
PVIGPRSRSYWETTNHVVFPRDFEPTLDANIQFAQSVLRQLSQDQGCAYLMPLRVKLDQY
LPPLMGALTA
>A0A1E1V5J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. BIWAKO-01|TrEMBL
MNAFRPSRHGTRRPSVSFEFFPPKTPEMETTLWESVRRLEPLGPTFVSVTYGAGGSTRER
THNTVKRMVDETGLKPAAHLTCVSATCAEVDDVIRSYWAAGVRHIVALRGDPAGGLGAVY
EPHPQGYHQTSDLVAGIRRVADFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRARGIDIPILPGIVPVLNFKQTASFATKTGASVPQWLADRFEGL
EDDAATRRLVAAAVCAEQVLDLIDRGVSDLHFYTMNKADLVYAICHLVGLKPDRTAQQQA
AAE
>A0A6J4KTH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Frankineae bacterium|TrEMBL
GRPHDQGHARERLTAVLLRVLPGEDRRGRAPAVDGHPAARAAAARLRVGDVRRGRLDPRP
HHRHDRAHRDRHHARAARAPHGGRPLDRRAAAHRRPARRRRGPQRPGPARRPAGGSAGRL
GQARPGAGVRRGARPAGQGLRRVLRRRGGVPGEAPTVAGRRQRHRALRRQVPRRGRLRHH
ADVLPRRRLPAPARPRGGDRLRGADPAGDHAGHQRRPDRADERPVGSGLPARARRRAARR
RERPRGSAPRRGRGGLDHVRPAAARGGARSALHHAQPLDRDARDLVAARPAVRGL
>A0A0N0DJ63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium leiognathi subsp. mandapamensis|TrEMBL
MSDQYLSSQESELRVRYNDITRGVYFIGTTPPKTSTPLEDVEGIADRLVDRICDLAIDGL
IVYDIQDEASRTNKPRPFPFKSTHDPRHYSSLLNKKTDKPVITYKSVVQSETEAFDEWLN
EAWDEYRVRDMVLVGSPSAKNEVSLPLSAAYQTLADNRNNFFTGGIMIAERHAKKGNEHE
RLIEKYKQGCNFFISQAIYDTQATIDILTRYAIECKEQGLKPQRIILTFSPCGSAKTLEF
IEWLGVSVPEATSLRILNAENPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRKE
EIDGSILLYKLLRSSMDSHLAKHEFRVLKRKARANKQASV
>A0A2I0NC85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetae bacterium HGW-Spirochaetae-6|TrEMBL
MNIDERLKTKKTFSMEVFPPKRDGDHLELLDVIRDLKSLNPDFISVTYGAGGTTRSLTKE
IASEIKNDIGIESMAHLTCVGNTRQEIGGILGELSQAGIHNVLALRGDPPQGEKF
>C5EAY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. infantis CCUG 52486|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWHNAEPLFRGTQG
>A0A0Q7B4D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root1257|TrEMBL
MRNKVANAQALTRLLSQARYEVLPTASTEDKVLAHVPRDVAVTVTASPSKGLDATFDLAE
RLAGHGYVVVPHIAARMVTGRSELAEICDRLTGKQITRIFVPGGDAEPAGDYPDALSLLE
DLTELGRPFAQVGITGYPESHPTIHDDLTVQSMWDKRRYATHVVSNLTFDPAVIRDWVHR
MRGRGITMPLLLGIPGPVDRTKLLSMATKIGVGESTRFLAKHKGTFARLAAPGGFTGERF
LEQCAPTLAEPTALVEGLHVFTFNQVAETEAWRQGLLARLG
>A0A2V2FYV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrionaceae bacterium|TrEMBL
MKIRQALEARKGPFYSLEFFPPKDPAEWPAFFGIVERLKSLDPLFASVTCGAGGSTRSYT
LDIASRLKRDYGLEPMPHLTCVGATAGSLAGALDGFREAGIDNVMALRGDKPRDAGPDWN
EGAFRHAEDLVRFTREERPGFGVGVAAYPAPHPESPSFRSDRDHLVHKIRAGADLVVTQL
FFDSREYFALADHLHEHGVDAPIIPGVLPIQSLASIRRTLSMCGANIPGKLYLQLEEAHD
KGGTEAVKEAGLAFAVDQIRRLLDGGAPGVHLYTLNRAELCLRIADEVGRL
>A0A2N5JT42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium M5B4|TrEMBL
MNNSFQAAIDRGDFLITAEVSPPKGTDVTTMLSHAQSLRGRVHAINITDSSRAVLGMSPL
AAAYLLQSQTGVEAIYQLACRDRNRIALQGDLLGAHALGLRSVLALTGDPVKAGDHPQAR
SVFDYEAVRLLQLIRKLNQGKDANDRDLPQGGTCLLAGAAVDPQSPSWSGLKARFQRKLD
SGAQFFQSQLITDFDRFAKFMDEIASLGNKPVLAGIFLLKSAKNAVFINKYVPGVNIPDR
IIDRLASAPDPLDMGITIAAEQIRQAQSLCQGVHIMAIKAEHLIPQILDRSGILDCKGKV
INDHSWD
>A0A5B8J2E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qingshengfaniella alkalisoli|TrEMBL
MSQPRVSFEFFPPKSLDASFKLWETVRALAPLDPSFVSVTYGAGGTTRKLTHEAVTTIEK
NYGLNVAAHLTCVDASRDETMEIVKAYSDAGITELVALRGDPPKGSGGFTPHPEGFANSC
ELIEALADTGKFNLRVGAYPDPHPEARGDPSADVRWLKRKFQAGAHSAITQFFFEPDTYF
RFRDACASEGIDAPIIPGIIPIESWKGVRKFATACGTPIPAWFDEAMTKAEDDGRTAEVS
AELCVDLCRKLLDGGVDDLHFYTLNKPELTKQICAQLGITPKKSLERVA
>A0A1J5D4V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium CG2_30_46_9|TrEMBL
MSKFRQVLNSGKFVVTSEIGPPKGTNIEKMLHHIDLLKDKVDALNVTDHQSSVMRFPSIG
GCLAIKEQGGEPILQMTCRDRNRLALQAELLLAYTRGIRNVLCLTGDAIPVGDHKEAKGV
FDLDSVQLLRAIRQMEAGKDLGGNELDGTIEFCAGAIVTPEARPIEPQLIKFEKKVEAGA
EFFQTQAVYDLDNFAKFMQYARQFSVKILAGIVLLSSASMAKYMTENVPGIFVPKYLIDE
LASAPRGEALNKGKEIAGRMVATLKKESICDGVHIMAIRREEVVPDILAIAGL
>R9HPB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus dnLKV7|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A4Y9JYJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus stratosphericus|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSIEEIKR
SFREQLYILLNEEPDGLLLETYYDIEEAKAVLQIARKETTLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPLLENSHLSVYPNSSLPSLEAGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHISAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKDAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMAKAGEDKEKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKESNIHVNYH
>A0A7C5LWC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hellea balneolensis|TrEMBL
MSAYKHDPNLGPVARTAGRGLDDLNISFEFFPPKTEKMQKTLWDSIQRLEPLAPDFVSVT
YGAGGSTRERTHETVAKIARDTSLSAAAHLTCVGSSKTEIEDIARAYWDAGVRHIVALRG
DPEAGIGERYQPMEGGYAYGSDLVAGLKSIAPFEISVSAYPELHPESRNLADEIDNLKRK
VDAGADRAITQFFFTPDVFLRFRDQVAQAGVDIPIVPGLMLQPNYKGMKRMADMCKISIP
DWYHRLFDGLDDEPEIRTLLTASTTAEMVAKLQEAGVNHFHFYTLNKADLAMTVCKMLGR
SPRAKADA
>A0A7C9JTP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas alkaliphila|TrEMBL
MINHNTGDACQAMKSTAYSSNGRLERVLKAGYFAVTSELAPPDSANPADVYARARIFDGY
VDSMNATDGSGANCHMSSVAMCALLTRAGYDTVMQVSCRDRNRIAIQGDVLGAAALGINN
ILCLTGDGVQVGDHPEAKPVFDLDSMSLLGVIAGLRDKKTFVSGRKISDPPQVFLGAAEN
PFVPPQDYRPYRLAKKIAAGAQFIQTQYCFDIPQFETFMAQSRDLGLLEKCFILPGVGPL
ASAGAANWMRNHVPGVHIPDAVIKRLEGAQDQRQEGRQICIEMIQQLREVAGVSGVHIMA
HRQESAVADIIDQSGVLGERRPWFPGSDQVCDAQHELPVGLSPE
>A0A8I0VQ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fulva|TrEMBL
MSVLKTALQQQQFACVMEFVPKPSAERFAAMDAIMARRQLCGWPMTLAIGDRVSSPLDMS
PLDALACFEHPVPALPHFSGKDRERHHLLAQMRRMDAAGQHQLLMLTGDRLPGHTPGKRP
VRYLESVAALQIARQTYPHWWLGAALNPFKYREEEGAAQYLKAEKKLAAGADFFILQLGF
DAAKHQEAMHWMRRQRAPKPMLACLMSLTQGRAGMLDHVAGVTVTPSMRQMLEAEAAQSK
AFAQARSIDRLALQVIGVKLMGYAGVHLSGIHEPSQLLALEARLAHWQTQVATLEQWAPA
WQASWQMPSLPAVTFHPPQAAWREGESRVVASFAQKARYHAMHGMHGLLFSRRNPVSQLF
GWAVRQPMWATGLGAQVLHSVERAVKRPLLGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTTLNRCEFGDRECIHSAKYRTAKAVRQTDVLAQRLIPCVEQHNRHRSSWPGWFGGKVQ
PVTRPSAPRSRRES
>A0A0K0DQ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Angiostrongylus cantonensis|TrEMBL
MVGQQSKYVPLHERIARRIQDKTPFFSLEFFPPKTANGVANFFTRLDRFNEGGPLFVDIT
WHLASDPANMNKETSSSSIAAGCLDYCRVDTMLHMTCAQYSKEQTIKHLEQSKSVGLRNI
LALRGDLNNTDTDYESTIYRYRALDMIRWIREEFGDYFTICCSGYPLGHPEAPSYKTDLQ
YLKSKCDAGAQFIITQLFFEAEVFEKFVRDCREIGITVPIIPGIMPIMGYDSIRRIAMLS
QLTIPQSILSDLEPIKHDDDAVRKYGTIRAIEMCRRILTNGSAPSIHLYTMNREGACRQI
LQELGLWHKRPMRALPWEPHGSNHPLRCKEDVRPIFWSARPKSYIYRTRDWDDFPNGRWG
NSSSPAFGDLNDYYLFHLKITQTKKEDLLKMYGEELRSFDDVKKVFKNFISQEANEHGVK
VTSLPWNEKEIGVQPETRLINDQLLWCNQNGILTVNSQPSVNGAPSTDSLVGWGKPGGYC
YQKAYLECFISKENAKSLLEIIDEFSPRINYHLINHDGSFDRMNGETTTPIAVTWGVFPG
AEIAQPTVVDPLAFRAWKDEAYDAWIKHWANLYPKDSDSRKILQKIHDEFFLLNVVDNDF
QRPVIIYEMLGKMLRKTKENSAFDGTLEESINEYEWLTGVNV
>A0A7Y3TPF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. CLA17|TrEMBL
MLSSSSLSSFHQAIQSGEFLITAEVTPPKGGDPTHMLSMAQLLKGRVHGVNVTDGSRAVL
RMSSLAASVILQQHGVEAICQVACRDRNAIGLQADLMGAHALGIHTILALTGDPVKAGDH
PTARPVFELESVRLLNLIHKLNEGLDFNDKPLPDGATSLLVGAAVDPQCGSWSGLQRRFE
RKLAAGAQFFQSQLISDFDRLEKFMTQVAVGSNKPVLAGIFLLKSAKNAQFINRCVPGVH
IPDEIIDRLGAAADPLHEGVVIAAEQVRLARELCQGVHMMAVKREDLIPQILDLAGIAPL
E
>A0A2D7JLT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nisaea sp|TrEMBL
MNMMRQQIISAASGFSIETTPGSAAKVANFADHLAAGTTVNVTYLAGSDAAETIAVCQRL
RDEGMRPVPHVAARNIESAGQLDDYLGALTXEAGVDEALVIAGGLDRPAGPXDCTMQVLE
SGLFGKHGIRRIAVAGHPEGSPDIHDDALAAALADKNQWAKENAVDMYIETQFCFEAXVV
LAWERRIRAAGNRLPIHIGVPGPATLKTLLKFAQMSGIGPSMRVLTRQARNLSRLLMVQA
PDRLVADLAIAMAEDPACLIAGFHLYPFGGLAKTSAWINAVAAGQFDLQDGGRFTVTEPL
KTAL
>A0A101VB49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium BRH_c3|TrEMBL
MSEILDPRHEEFTAHDSPLFAALPGDLSISFEFFPPKTEKMEAKLWDTVEQLKVLDPAFV
SVTYGAGGSTRERTHATVARIITEAGLPAAAHLTCVDASKAEIREVAEQYWEAGVRHIVA
LRGDAGEPGAPFVPHPEGYRNAAELVAGLKQIADFEISVAAYPETHPDADCPQSDIDNLK
RKLDAGASRAITQFFFSADTFFRFRDELARQGIDAPVVPGILPVTDVAQARKFAGACGAA
IPAWMDGLFEGLDERPAARQLVAATIAAELCRRLYAGGVRDFHFYTLNRPELSYAVCHLL
GRRPTGGAS
>A0A366DXM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudochrobactrum asaccharolyticum|TrEMBL
MSSFGQQRRSESAHPIRVSFEFFPPKTEEMETRLWETVTRLAPLNPAFVSVTYGAGGSTR
ERTNKTIARIIKETSITPAAHLTCVDATKEEVNSIVRSFASLGVTRFVALRGDPAGGIGE
AYQPTPDGYQNGADLVAGLKSIADFDISVSAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGVLPIHNFKQVANFSKRAGTRIPAWLADRFD
GLDNDPQTHMLVSAALAAEQVNDLIERGLNDFHFYTMNRSDLAFAICHLLGVRAPVAA
>A0A426YI58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensete ventricosum|TrEMBL
MKVIDKIQAAAEGDGRTVFSFEFFPPKTEEGVENLFERMDRMVAHNPAFCDITWGAGGST
ADLTLDIANRMQNMVDLSHRYADILICVETMMHLTCTNMPVEKIDHALDTIKANGIQNVL
ALRGDPPHGQDKFVQVAGGFACALDLVRFQFFSLVQHIRAKYGDYFGITVAGYPVFSILE
AHPDMIQGDGGATLDAYDSDLAYLKRKVIYIIFVYMIIVHYDLTNNILQIPSEITAALEP
IKDNEEAVRAYGVHLGTETCRKILAHGIKTLHLYTLNMEKSALAILMNLGLIEESKVSRS
LPWRRPANVFRVKEDVRPIFWYHLLFIFRHLRITWLLPVLWMMLEGYGLDLFLFADLNRA
NRPKSYISRTVGWDQYPHGRWGDSNNPSYGALTDYQFVIVSHSQAQRSYYLVSLVDNDYV
HGDIFAAFKDI
>A0A4U0U810|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinomyces thailandica|TrEMBL
MHITKKLAAAHGEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
NLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLRDAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDDETDADGHIPYLKEKIDAGGT
FIVTQMSYDAEIFIAWAKKVRAAGVPDNVPIIPGIMPIQTYDSFLRRAKWTQCRIPPDWM
EALEPIKADDAAVREVGKRLVANFCRRLLDSGVTMHLHFYTMNLEKSTYMVLEELAVTPP
SDQHDPDLKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEHNKKLWGEPKSLQEVADLFVKYMSGKVETLPWSEQPISSESNVL
TEDLVTLNSRGLLTINSQPSVDGMKSSNPVYGWGPRNGYVYQKAYLEVLIPPSLIEELIR
RMDANADITYYAVNKNGELKTNAPQDGGPNAVTWGVFPGKEIVQPTIVETISFLAWRDEF
YYLGSEWARCYDEGSDSRNLIKEITESWYLVNIVDNDFRNERGIFPLFDGLKVDGIEPKT
AVKSAVQTNGDAHADPEGKEGTQKPELNGVPDKNNAVDHADTQANGQVKND
>A0A0W8IEI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serinicoccus chungangensis|TrEMBL
MSTTSRISVELVPRSPESVRSEMAQVAARLPVVDTINIPDLLKFDLRSWQATEVAREATT
RGDGAAYRTIPHIRAADVDPDAELPMAREARRTGELLVVSGDDADYFHSATYPVDAVDVI
RRLRSELPGVTIYAGLDPYRQAMTTEMRYLDRKLAAGASGIFTQPFFDLHLMSAWASVLP
PELPVWWGATSVTTDGAMGYWRRRNRVVFPRGFDTSIGWQRDFARRVVDFARDRGHHAYL
MPVRAPLLDYLGGVLDEA
>A0A2U8Q0T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium amphicarpaeae|TrEMBL
MTDLTIPARANGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTPYSSHPDGYQSSADLVAGIKKRHGDVEVSVSAYPEKHPEARDFDADIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDDDVETRKLVAATVAAGQVQKLAKNGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A432VCC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudaminobacter arsenicus|TrEMBL
MSSLGFSRRSDIGAKIRVSFEFFPPKTDEMEARLWDTVTRLEPLQPNFVSVTYGAGGSTR
ERTGRTIKRILNETSIPAAAHLTCVGASKEEVNAVIAEFASIGITRFVALRGDPASGVGE
VYRPHPGGYHNGADLVAGLKAHGDFDISVAAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGIQPVHNFGQVARFASRAGAHVPAWLAERFE
GLEDDPQTHALVASAVAAEQVLDLVDRGVSDFHFYTMNRSDLVVAICHMIGVRANPPVEK
ALAGSAAA
>A0A7X9FUN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKVSEALIGRKKPVLSLEILPPNKGSNVEELYRLVDPFLEFDPLFISVTFHQPQNRWSVE
NGQEIKIHRQRRPGTVALSASLKHKFGVETVPHLICAGYNRYELEDALLELHYLGLENIF
VIRGDPQPGEKEFRPEPGGPTYACELVKQIDNLNHGYYLEGVKPAASTDFCCGVAGYPEK
HPESPSLEFDLFHLEEKIEAGARFIITQMFFSAEIYRNYLGRLKKAGIKVPVLPGFKLLY
NQKQLAKIPATFRVSLPPAMVEAFEACRTPEEEKKTGLKFGLKLAENLLESGAPGIHIFT
MSQKDPVLDLLKILFKR
>A0A7V4Y1F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKTKSNIERLLEKGVFVVTSECGPPRGADPEAVRKKGNLLKGVVDAVNVTDNQTSVVRMS
SLSSCLILKEMGFDPILQMVCRDRNRIALQSDILGAAALGINNILCLSGDHQKFGDHPRA
KNVFDIDSIQLIHTVKTLRDEGRLLGGDEIKGRPALFIGAAENPFADPFEIRALRLGKKV
KAGCDFIQTQCIYNMERFSRWMQMVRDRGLHEKCAILAGVTPLKSAGMARYMKTSVPGMD
VPDSLIDRLKGVPKEKQAEEGIKICVEMIQQLKEIPGVRGVHIMAIEWEEKVAEIAQAAG
LLPRPQL
>A0A2V9WW11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MAADLLARIKQSAVLCDGAMGTLLYAKGIFINRSYDELNLSQPELIRSVHHDYLQAGAEI
IETNTFGANSFRLARHSLADKARDINVAGARLAHETAKSFDVWVAGSVGPLGTRIEPLGK
TSFEEAREAFRQQIAALVEGGVDLLILETFGYLEEIHQAMLAAHDVNVKLPLVAQVTIDE
DGNCLDGSDPGTFVPKLMEWGADVIGCNCSVGPVAMLDVIERVRTLTSLPLSAQPNAGIP
RSVDGRNIYLCSPEYMASYARKFVAAGARIVGGCCGTTPEHIRVMKAALRVGEARGKVAS
ARVVGAAAAPKAIPALRLEERSPLGAKLARGEFVTMVEIVPPKGIDINKEIEGARFLKSV
GVDGVNIPDSPRASARISNQALSLLIQQEVGMQAILHYTCRDRNVLCIQSDLLGAAAVGI
RNLICITGDPPKMGNYPDATAVFDVDAIGLVNIVHNLNLGLDIGGNPIGTGTGFVLGVGA
NPGLTDLDEEIRRFEYKVEAGAEYAVTQPVFDINLLETFLGRIEHCRVPVVAGIWPLVSV
RNAEFMKNELRVSVPDSILQRMAAAQNPEAARAEGVAIAREMLTSVRQMVQGAQISAPQG
RYNLAVDVLEALGTNSPASV
>A0A7W1LPV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
ADLLGAHALGLRLVVCRTGSPRVAGDYPDPAQPWDVDSVRLIAALRGLNEGLDWRGVATR
ERTHFVIGGSISTAAVDVGREVDRAEAKAHAGAHFLVTDAIYDADRASQLLAALPLRGID
VPVIASIAPFESFRTLERMRHEVPEMSMPADQMGGRRRIGVAPGEAVEACLRVVEKLRGL
ISGVLVQIPRESQQPAVELVRRLADLTSHA
>A0A7X9PRX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKPFLLLAELVPAQGDDVRPIECFLRDYAGRKSEIPSGFRLAGVALPQNPRGIPMLDPAD
IFSIIAAKGPSGRGLWDDLDVVPHVTGKEQNAEALRSALMGFRAMGLTTVLAITGDKPAS
GKRVFELDSIGLLELVSELNFDAFQRAPVSPPAKRTVPSPEHPPAPGGFSRIGEMLAGPR
PGSASFASRFSSVPQFFALAAVSPFKYTEASLLQQYFKAAKKLQAGAQAFLLQMGWDSRK
SEELFRYFRQARLDAPVLGNVYYLSNANPAARLMNEGRMPGCFVSDELLAAVRREKAEAH
LERAACQVAMYRDLGADGVDLGGLPDFDALVRIAVRAGEIGPGWRQRRIILDYPPPPPAS
GPGLFYLYGPETEGGSAPRPPFRPSPRPRTFRQRRFDFLHRNFLTKGKRLCPAVAGTARA
FGLEKGEGSLYRWFHGAEAAAKAVLFACEDCGDCFLPENFGYCTLGECAKGLPNPPCGDA
TPEGRCGNDETRVCVAEPIFQAAAAAGKLDGLAETALPPRIAALEHTSGVLNYVFDRDHA
RGFPLIQIAELLHASIPRTAAAVQEVIKEGLIGAPPGAVRASGSAALGYLVSLIRRQAKQ
GAAYIDVNVDALSEDDPEFRKEILRFFVRLIRGHSLGVPVCIDSGSTEMLEAGLAAWYEG
GREGGRPSAAPLVNSVKTYTMERLLPLRARFPFKFIGLLVDEKTAGLDGAYGVEELQALA
RRIVRAATGSHGFAPGDIFLDSTVFPLSIDVPMEAAKPGYTFRAFETIRRLKADPEFRGV
HFSLGVTNAVRDLPGRRTGVTRAYLARAMELGLDAAIVNVFHGYGRRPPAPDLLAFVDAF
ARQDGSPEAVENALQAMMDFCRANRKK
>A0A2V8QC17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MLPFRELLESDGIHVVDGAMGTMLYAKGIYINRCYDELNLSNPDLVREIHCEYIKAGADI
IETNTFGATAHNLQQYGLEANLHEINVLAAKIAREAAGERAYVAGAIGPLGLRIEPYGPT
SFDEAKDLFKAQAIALLEGGVDLFCLETFSDVSEIRQAIRALRELCDLPIIAQMTIMTDG
NTVFGTTPEIFTERLDQWGADVIGLNCGVGPAIILNALEKMRAVTKKKLSAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRFIQSGAKFIGGCCGTTPAHIKLISDAVRAASPRAQRIAFT
PGTPAHVDEITPADIKVVPPEERSRWGYKIARGEFVTSVEVLPPKGVDSKKTLDSIRLLK
DAGVDGVNIPDGARAQSRMSALATAVLVEQQIGIESVLHYCCRDRNLLGMMSDLLGAAGL
GLRNILVITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGEPTAFCIGV
GVNPGAINLDEEIKRFEWKVEAGAQYAITQPVFDTDQLRDFLKRIEHVRIPVIAGIWPLV
SYRNAEFLHNEVPGVRVTPSIMDRMRDASAISKEAGRDEGLKIARESLLEVRDVIQGVQV
SAPFGNVKYALEVFGALEEFQQAAS
>A0A2V9S5J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MAGDLIARLNKAPVLCDGAMGTLLYGKGVFINRCYDEMNVSQSDMILDLHRQYLQAGAEI
IETNTFGGNRFRLERHSLADKVAEINAAGARLARTAAKSFDVWVAGAVGPLGIRIEPLGK
TSFDEARATFREQIAALVEGGVDLIILETFGYVEELHQAVLAARDVAPKLPVVAQVTIDE
DGNCLDGSTPETFTPRLEEWGVDVIGCNCSVGPVAMLDVIERVRALTSLPLSAQPNAGVP
RSVEGRNIYLCSPEYMASYARKFVTAGVRLIGGCCGTTPDHTRVMKSALRMGEARSKVAK
PHDAGGSKPVAAAALPLDQRSKVGAKVASGEFVSMVEIVPPKGTDIRKEIEGARFLKSVG
VDAINIPDSPRASARMSNQALSLLIQQEVGIEAVLHYTCRDRNVLGIQSDLLGAAAIGLH
NLICITGDPPKMGNYPDATAVFDVDAIGLVNIVHNLNRGLDIGGNPIGTGTAFVIGVGAN
PGLPNLDEEIRRFEYKVEAGAEYAVTQPVFDLSLLENFLRRIEHFRIPVMAGIWPLVSVR
NAEFMKNELRVSVPDSILERMVRSKTPEAAREEGIAIAREMLIAVRSMVQGAQISAPLGR
YASAVDVLEGLGTSHSASV
>A0A7V8XYM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MVRTPFLDAIEQRVLVCDGAMGTMLYAKGIFLNRSFDELNLTQPDLVAEVHQGYVRAGAD
VIETNTFGANRIKLGAFALADKVHTINLQGAKIARHAARDRAYVAGAIGPLGIRIEPWGR
TGVEETEVYFREQAKALHEGGVDLFVLETFRDLNEISAAIRAIRSVCALPIVAQVTTEQD
GNTLDGVAPESFVPHLQDQGANIVGLNCSVGPAAMLETIERMAQVATVTLSAQPNAGSPR
EVEGRNIYLCSPEYMASYARRFINSGVRLVGGCCGTTPDHIRQIKTAVRALAPAAPPRDK
ATATVPAVARVEVVSRAEKSRMANGLARGVFAVSVELVPPRGYDAHALIEQARQLRIHGV
DLVNIPDGPRARARMSALSASVIVQQQTGVDTILHYACRDRNLLGMQSDLLGAHSMGIRN
VLLVTGDPPHAGDYPDATAVFDVDSIGLTNVVARLNQGLDIGGQPIGAPTAFHIGVAVNP
SAIDLDYEHRRFRYKVEAGAEFAITQPVFDVAALVTFLEQSDARIPVLASIIPLASLRHA
EFMANEVPGVSISAAVVDRMRRAEVAGRGAAEGLAIASEIVAEVRPHVQGIQISTAAGAI
ESALGVMKALAA
>A0A2V8FFA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MQDFREALARRVLVCDGAMGTMLYSRGVFINKSLDAMNLTQAGLVEGVHRAYVDAGADIL
ETNTFGANRIKLASFGLADKLHDINVAGAHIARRAAGDAAYVAGAIGPLGIRIEPWGKTG
VDEAREYFREQVAALLESGVDLFILETFRDLNEIGAAIDAVRSLSDLPLVAQMTTEEDGN
TLDGTPPERFAPELQKRGATVIGVNCAVGPGPMLETIERMEAVTDISLSAQPNAGKPRDV
EGRNIYLCSPEYMASYARRFILHNVRIVGGCCGTTPEHIKQIKAAVGTAGSAAAAPHVVT
PRHRPSPASPATVTVMAPPIPPEQKSRLARALADGRFVVGVELLPPRGFEAEPAIQRARE
LKRYGVDVVNIPDGLRAGARLSALSLAVLIEQQAGIETLLHYSCRDRNLLGIQSDLLGAH
AMGLRNLLLITGDPGRVGDYPDATAVFDVDSIGLTNVVTRLNHGCDVGGQAIGVPTGFHL
GVSVNPAAPNLDEELRRFDYKVQAGAEFVLTRPVFDVASFERVLPSIARARLPVIAGVFP
FESARNAEFLANEVPGVRVPENLLDRMRRADGPDAAAAEGIAIARDIASSLRASVQGIQV
ATQSGNVDAALAVLDGLR
>A0A399WQ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRKFRDLIGGEGVYVFDGAVGTRLYDKGIYINRSYDELNLTQPDLVKEVHDEYVAAGADI
IETNTFGATRPKLLPYGLESKLHEINVAAAQIARQSAGEKAFVAGAIGPLGLRIEPFGPT
SFDEAKGFYLEQVNALLEGGVDLFVLETFSELEIIEQAIKAVREASDLPIVAQMTIQMDG
KTAFGSTPETIATRLDELGADIVGLNCGMGPNHILNALEKMRAVTSKDLSAQPNAGLPRD
VQGRQFYMGSPEYMATFAKRFVSAGARFIGGCCGTTPTHIKLIADAVRSISPRQAISEAR
SQIVAVAEIKPPDIQVVRREDRSLWSKKIARGEFVTSVEVLPPKGCDAEKTLESIRLLHE
AGVDGVNIPDGPRAQTRMSALATAVLVNEEVGIEPVLHYCCRDRNLLGMMSDLLGAAALG
LHNLLLITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGKPTEFSIGVG
VNPGAVNLDEEIKRFEWKVEAGAEYAITQPVFDTEQLMHFLDRISHVRIPIVAGIWPLIS
YRNAEFMHNEVPGVNVTADILERMRIASDQSKEHAREEGINIARESLLEVRDSIQGVQVS
APFGNVKYALQVFEVLE
>A0A7W1KZD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
NKLNHGLDLGNNPIGQPTAFCIGVGVNPGAINLDEEIKRFEYKVEAGAQYAITQPVFDTE
QLSDFLKRIEHVRIPIVAGIWPLVSYRNAEFLHNEVPGVRVTPSIMERMRVASEKNKEAA
REEGLKIARESLLEARDQIQGVQVSAPFGNVRYALEVFDVLDEFGAKRNNKVSVVR
>A0A6I4JUW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. PB120|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRDLLSQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIRTETGDHFHIEVAAYPEMHPQARDFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDAQSIQGFG
EQVITQMCERLLEGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A2V8NAJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MNDFLSALEERVLVCDGAMGTMLYSKGVFISRCFDELNLSNPQLVREVHADYIKTGVDII
ETNTFGANITKLMSHGLADQARDINLQGARIARDAANARPGGTSGHKVFVAGAIGPLGIR
IEPWGKMSIDEARTIFRGQAQALIDGGVDFFILETFFDLNEVHAAIRGIQDVSDLPLVVQ
MSVEDDGNSPEGTPPEVFAKRLDEWGAEVVGLNCSVGPQAMLDAIERLATVTSKKLSAQP
NAGKPRSIEGRNIYLCSPEYMASYAKKFVQHGVRIVGGCCGTTPEHIRAIRAAVQGHGLQ
GMRGSQSVRSVEPTAISDPRPLETKSRLGAKLARKEFIKIVEMIPPVGHDYTAAIEKAKY
LEAHHVDAVNVPDARRSSARMSAISLAILLERSTEIESLAQYTCRDKNLLGMQADLLGAY
ALGLRNLLLTTGDPQQMGDYIDATAVFHVDSIGLTNMVQRLNQGIDVGGKSIGMPTGFVV
GVLANPGTINNDAEELNRFQYKVQAGAEFALTPPVFDVGVLERLLRRIEHYKIPTIMGIL
PLPNFKTAEFMHYEVPGCSVPEHILRRMRSAEAESLDRARAEGIAVAREILHAVRTMVQG
VQIHGPFEQYETALEVLS
>A0A2V8E2E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSADVLTALTDGTFTFAAELRPPRAELADREGMDAWIDTYHAVRGLTRHGTYVFLTDSAV
GANEEDNLRHMVANLGRDVPREHVVPFLTTKHSLEYCLSYAERARQSGFPALVVLGGDRS
VGGKRCVEHAWQLRERLRAQDPALKLGGWANPHADPQRQVEFLTAPQFNAEFYLTQVVSH
HDIDSVRRFLDAAKRGGVSLPAVFGVFYYRSANRGTLEMLKGFLPVPVEQLTREFAAGAR
PEEVCARTVRALAEVGIRHFYISNLPIRSTHSALATVGDLARI
>A0A1F3M9L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWF2_41_31|TrEMBL
MEKTIIQYLAEAKKPLFSFELLPPLKGHNFDSIQQAIDPLVKFDPAFINITYHQQEVVYE
NLPNNLMKKHTVRKRPGTVGISAAIKYRFGIDVVPHIICGGFTREETENALIDLQFLDIN
NVLVVRGDPQPGTRIFVPEPDGNEHALDLVKQITNLNKGIYLDADLLNTRSMNFCIGVAG
YPEKHGESPNLDSDLYFLKKKIQAGASYIVTQMFFDNQKYFDFVTRCREKGIMVPIIPGL
KPFTTASQLTAIPKTFNVDIPVDLVKEVIKCKNNQQVRQVGVEWAIQQSKELYAAGVPVL
HYYTMGKSDNIEEIAKAVF
>A0A1H5M9V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruania alba|TrEMBL
MTTATLYRSPRPDPCVSFELYPPRTPKGEQTLTRTVGALAEIQPDYFSVTYGASGSTRNT
SRDLIGRILSGTPVTPLAHLTCVGASEEDLSEYVSSLLEAGVRDFLALRGDPPAGQPDWR
PHPDGLTRASQLVHLLRRLATEHLGSDGADVSISVATYPGGSYDESGRPVVCPNDVSALL
EKQAAGADFAITQLFYDARHYAELVQAARAAGVHIPIVPGLIPLTDPNRLRRMVELTGVA
VPPVLLEHLDEAADKEEAYRRGLAASVRLVREVLETGAPGIHFYTFNSSRAVLDLLHASG
LR
>A0A5N9I443|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MN1F|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKDELRSLLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEADLGNFVHKVKAGADSAITQYFFNADSYFY
FVERAQKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLAIWNNLKLPR
>A0A356PRV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp|TrEMBL
MSKRISFEFFPPKTEQGREKLLNTQQKLLAKKPEFFSCTFGAGGSTRDYTRQMVDLLREQ
HADTAPHLSCIGQSRDEIMELVNGYKESGVRRIVALRGDLPSGMGYAQSEVKYADDLVAL
IREETGDHFHLEVAAYPENHPQSRSFDDDIAHFQRKISAGADSGITQYFYNADAYGYYMD
ELRRRGCDAPVYPGVMPILNVANLFRFSDNCGADIPRWLRSRLDDIRDD
>A0A1H3Q761|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis xylanica|TrEMBL
MSDMTSVIERLRGDTPAFSVEFFPPRDEADEAILWRSIRELEPFDPAYMSITYGAGGSSR
DGTIRNIARAATETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYG
DWVAHPQGLTYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTHFLVRKLRAGADFA
IAQLFFEPEDFLRLRDRVAATGCEAVMIPGIMPLTTPRTLRTTIKLSGASAPRSLLDRLE
PLAGDAKAFRAEGIDVVTELGERLLAEGVPNLHFYTFNRSKATREVVNRLGLVPARA
>A0A1I5DC90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus japonica|TrEMBL
MSFFHANQREALNQNLAELEGQFRVSFEFFPPSTAEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKEKTGLDAAPHLTCIDASREELRNIAHDYWQNGIRHIVALRGD
LPTNCCSKPEMYGADLVELLKEEADFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANR
AITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATITNVRIPSWMTRMF
EGLDDDPESRSLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPS
>A0A2E6RHS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MSLSPQLSFEFFPPKNDEQVELFKRTRDRLAALKPEYMSVTFGAGGSTRSRTRETVFNIQ
RETGIPAAPHISCMSEDIDSIDELLDSYREYGIERLVVLRGDRPSGGGSGIFDYATDLVR
HIRKGYGDQFQIEVGCYPEYHPEARSPEEDLKHFKEKVDAGADSAITQYFFNADAYERFL
EDCARLNIQVPIVPGIMPITNYSRLARFSKMCGADMPTWIFKRVRAWEEQEDFKSIRQFG
EDVITDLCRKLIDLGAPGIHFYTLNRAQASLKLCRNLGLGEGNEAGDTRAA
>A0A7Z2Z696|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas hydrophila|TrEMBL
MGFHSARQVEALNQSLADLGNNISVSFEFFPPNSEGMENTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNFQTLNKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQA
>A0A7V4U0S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldithrix abyssi|TrEMBL
MKVTEHLSKAKNTLISFEIIPPKRGGDIKSLLKVVDDIARYNPPFIDITSHAAEVIYEET
PQGIERKVKRKRPGTLGICALIQNKYDIDAVPHVLCQGFTREETEDFLIDLQYLQIENVL
AIRGDESNYKKPLLHGRSANIFAADLVEQIANMNQGKYLEDSLVDARPSDFCIGVGAYPE
KHFEAPNLETDIQNLKKKIDAGADYIVTQMFFDNSVYFRFVEKCRQAGIDAPIIPGLKIV
TSAGQLTNIPRNFFVNIPVELTRRISSANPSDVLKEGVEWTFRQVRELLDNNVPAIHFYI
MQDSKPIRMLMERLGR
>A0A8J7FYP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinilyticum piscinae|TrEMBL
MLQDLIRQRTNGIVLYGITPPKAQNTPEKIAEIAATQVERIRSLGVDGLVLYDIQDEADR
TSEARPFPFIETLDPVMYAAEHLASLDLPKITYRCTAKYSPESFTAYLQAQQQGLAVFVG
AASRQQRVTLTMNDAYALRQQHSPDLLLGGVAIPERHLVKQDEHLRVAAKMAQGCSYFIT
QCVYNVEAAKTFLSDYYYHCREQDIDMVPIIFTITPCGSVKTLQFMKWLGISIPKWLEND
LSHSVDILGDSLNACRSIFAELIEYAASKQIPIGCNVESVAIRKDEIEASLQLVRDVQAM
LGR
>A0A831R2N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter antarcticus|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQVVRDQLAGVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTREEIAELLDLYKENGINRIVALRGDMPSGMGAAGEMRYAN
ELIAFIREHSGDHFNLEVAAYPEFHPQARSAEDDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKLGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDKESIRK
FGEEVITDMCERLLKAGAPGLHFYTLNQAEPSINIWKNLGISEREKIAF
>F8IJ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicyclobacillus acidocaldarius (strain Tc-4-1)|TrEMBL
MSDAVWREWRRPPRDVEGSLGVFVIFDGAMSTYLHQLGVPIGTPVEQLNLTSPDLVARVH
RRYVESGCTVLQTNTFMGNRVALERHGLSVDVASLNRRGVEIARSAAHGEASVYGTMGPA
MGGYRYGALLQDDERDLLAHVYAEQAEALVSAGIDGLILETFPDLEEALVAIAAVRPLLG
DLPLVVNLSPEEIGVTRDGVPLAEAFRRIRAAGADVVGLNCRLGPYGILRSYEQAGLSAE
GPYAAVPNAGILQRSEADEIAYTGDTEDFSRLMLRIAQLGVRWLGGCCGTTPEYIRSLRD
ALMRADRKPHGATVPADTRGPSGPSRVTLGAGGYHEGVSVVEIAREKKAIVVELDPPKHL
SIARFLDGAEALARAGADLITMADNSLGSVRVSNMALASLLKQRGIEPLVHVTCRDRNLI
GQQSHLMGLAVLGIRNVLLVTGDPSRYGELPGATSVYDVSSMDLTKMVRRLNEGIGFSGQ
PLKQPSRFVIGTAFNPHVHNFRKAVERLQRKVEAGADFVMTQPVFDPDLMAAIAEATRDL
GVPVFVGIMPLTSARNAEFLHHQVPGIRLSEQALRRMQEAAPEEAPAVGEAIARELVEVA
IRLFPGLYLVTPFLRYEMTVRLTEYARRLEATLVSRPHGHA
>A0A1H5SY39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. UNC499MF|TrEMBL
MKPELRQVLAQKILIGDGAMGTYLYQQGFPVGISYEELNLIQSEVVADVHRRYYEAGARL
IETNTFSANREKLSKYGLEQEVEAINRAGVELARSSVGEDAYVVGAIGPIRAGMRKNVRT
ADVEDALREQILVLLDTRVDGLLLETFYDLEEMLIALRLIRQLSSIPVICQFATEGINTT
HDGISLQDAFLRLKEEGADVIGFNCRTGPNGILRSLQGVAQLRDIPFSVFPNAGIPDYVD
GRYSYAATPEYFAESALRFADLGARIIGGCCGTTPEHIAAMVKALQGYEPKRSEMYAAES
VSAAERAVVTEAAPQTSALEADAEPTLVDLAKRRHTVIVELDPPRDLDIGKFMEGTKALQ
DVHVDAITMADNSLAVTRMSNLALGMLVKEQHGARPLIHIACRDRNSIGTQSHLMGLHAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEMIRMIKQLNEGIAFSGKPLKKKANFIVGA
AFNPNVKYLDKAVQRLERKIESGADYIMTQPVYDPKLIERMHEATKHLDVPVFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMAGLEGEAGRKEGVAIAKELLDAAMPLFNGIYFMTP
FLFYDMSVQLTRYVWQKAERREFLLSPLLK
>R5IRD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:7|TrEMBL
MKIKDILAEGRPTLSFEVFPPKTADAYESVEKAASKIAQLKPDFMSVTYGAGGGTSDYTV
KIASTIKEEYGVTPLAHLTCVSSTREKVHHVLEELKAHKIENVLALRGDIPQDGKTPEVY
HYASELIHEIKEAGDFCIGAACYPEGHPESSNKSVDMDYLKEKVDAGCDFVTTQMFFDNS
LLYSYLYRIREKGITIPVIAGIMPVTSGSQLKRIAQMSGSYMPARFLSLVDKYGDNPAAM
KQAGIAYATDQIIDLLANGIKGIHVYTMNKPDVAAQIQSNISELLK
>A5WA10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1E4GQ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium sp. SCN 70-31|TrEMBL
MSPADTALGPVARAGAGAGSPPRVSFEFSPPKGPKSEESLWEAIRRLEPLNPEFVSVTYG
AGGSTRERTHRTVVRILKETTLRPAAHLTCVEASRAEVDEVIRDYWDAGIRHIVALRGDP
PGSLGGAYTPRADGYQNATELTAGIKAVAPFDVSVGVYPQIHPESPSIDHDIEVLKAKID
AGATRAISNFFFDIDGYLRFVDRIRKAGIEAPILPGIMPVSSFEGLSNMAGRIGVAIPPW
LANHFEGLDTDPETRRLVAASVAAEMCARLAEEGFSDFHFYTLNRADLVYAICRVLGVRE
APPAEAKEAAA
>A0A1P8UKB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidihalobacter ferrooxydans|TrEMBL
MTDTPHNGREFSCEFFPPKTPEGAARLDHVREQLAALGPRFFSVTYGAGGTTQARTLETV
LRIQHESGIPAAPHLSCVGSTREQIRGILDTYRTNGIQRIVALRGDLPSGMRDIGEFRHA
NDLVEFVRAETGDHFRIEVAAYPEVHPQARNAEEDLRHFKRKIEAGANSAITQYFFNPDA
YFRFIDDCARCGIDVPIIPGIMPITQYTQLARFSDACGAEIPRWMRKRLEGMGDDRDAIR
AFGLDVISALCQRLLDAGAPGLHFYTMNQAEATQEIWERLGLSGA
>A0A1F6GFD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lambdaproteobacteria bacterium RIFOXYD2_FULL_50_16|TrEMBL
MSYKKHIKSILGSNRHVSFELFPPRTNQGLRQIYKSIAQLQKLGPDFFSVTYGAGGSTAE
RSLDVASAITNLASQTCVAHFTCVGMDRPQVLALLGQLEFHGINNVLALRGDPPQGAEQF
VRPENGFAYASELVAFIRENAPHLGILVAGYPEGHMENPDKENDFRRLVDKVKAGADGIV
TQAFFENRYLFDFAQKLDQAKVTVPLLAGIFLFSNARQVTRIFELSGGKMPAKLEAGIKK
WGEDADAMQKFGTEFAIEQVDDLVSQGFGHFHFYTMNRSDQAREVLQALEHHFPRLRFD
>F7ZH72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseobacter litoralis (strain ATCC 49566 / DSM 6996 / JCM 21268 / NBRC 15278 / OCh 149)|TrEMBL
MPIPAVSFEVFPPRSIDASFKLWDTAQALAPLAPRFFSVTYGAGGTTRDLTHDAAYTLHK
SSGLPVAAHLTCVGASKAETLAIAQRFAQAGITDIVALRGDAPDGSTGFTPHPDGFANSV
ELIEALSRSGQFTLRVGAYPEKHPEASSQQANIDWLKAKVDAGACEAITQFFFEADTFLR
FRDDCARAGISVPITPGILPITNWTNARKFAQRCGTSIPAWLDQAFDAALRDDRHDLLAR
ALCTELCSDLVDEGVDSLHFYTLNRPELTREICHALGVTQAVTGVMDVA
>A0A1I4YWP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salegentibacter flavus|TrEMBL
MGFLTNLEGTMKITEHIKAAKGRSLFSFEILPPLKGQNIQSIYDGIDPLMEFKPPFIDVT
YHREEYVFNDQGNGLLQKKIVRKRPGTVGICAAIQSKYGVDAVPHILCGGFSKEDTENFL
IDLDFLGIQNVMALRGDAVKSETYFTPEKEGNHFAKELVEQIGDMNQGKYLDKVIEKGHN
TDFCVGVAGYPEKHMEAPSLDKDIKRLKEKVDAGAEYVVTQMFFDNQKYFEFVEKCRVHG
ITVPIIPGLKPIATKRQLSIIPHRFHVDMPEDLIHEVEKCKDNKEVREVGVEWGIYQSKE
LIAAGVPVLHYYSMGKSTNIQKIAKAVF
>A0A5J5K5G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbispora cellulosiformans|TrEMBL
MALGLPSRLPDRVPTVRELLAAGERSFSFEFFPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPRGGNPLDEWVRHPEGVLYAEDLVRLIRQAGDFCVGVAAFPYKHPRSATIESDTNYFV
QKCRAGADYAITQMFFRAEDYLRLRDRVAAQGCDTPIIPGVMPVTQMSTIARSEQLSGAP
FPPEVAERFAAVADDPVAVRRLGIEHAAEMCQTLLDEGAPGIHFITFNRSSATREVFKAL
HGVPAVAG
>A0A8H5HDB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tricholomella constricta|TrEMBL
MKLIDKIAADKSSHPFYTFEFFPPRTDQGFENLIARISRLCTLNPLAISITWGAGGSTRE
RSLELAGLTQTEYGVDTVLHLTCTNMEQGMVNDALRSAKARGIQNILALRGDPPRGQEEW
IPIDPRFQHAIDLVKFIRSSPEFSPEFCIGVAAYPDGHTDSHLDEDTELTYLKEKVDAGA
DFIVTQLFYDVDRFFQWLKKVREKGITVPVIPGIMPIQTYSSFLRLTKLCGTRVPQYILD
ALGSISHDDQLVKDYGVKLAVDMIQRLTKNGDVPGVHFCTLNLEKSVQRVLEFLQWTGVA
APVHNRLIAETPGYNPPPSIDTSDLLVTPVTATNSATLGLANIPPTETEAGRGELNNAAT
WDDFPNGRFGDFKSPAFGNQDPWGGPALRNDEVSQWGHPKTLDDLTQLFLDHLHSKISTT
PFSPTPLSPESLMILPHLEKLTKRGWWTVGSQPAVDGASSADEVFGWGPRSGYVFQKGFV
EFFCSAEDVDVIERRVEERGKGWVHWFAGDVKGECRGNVPENDRNAVTWGVFPGQEIAQT
TIIEKESFLSWKEEAFSIWSDWASFYRPGSEERKLLEGVRDERWLVSIVHHDYRNTEALW
TFLFEEP
>A0A854XV60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium phaseoli|TrEMBL
MALKNEAQARNIGISFEFFPPKSEEMEGQLWNTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRRAGISIPIVPGIMPIQNLTQLKRFAGACGAVIPGFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIRDFHLYTMNRSPLVSAVLDNLGLSRRPAKNAGAAA
>A0A6A6K2M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hevea brasiliensis|TrEMBL
MMLCLCRGSSGYDRKRWVATPENYQKDLEYLKRKVFLLPVLVNTTEVTAALEPIKDNEEA
VRAYGIHLGIEVCKKILAHGIKTLHLYTLNMEKSTLAILMGFSMSNLGLIDESKITRSLP
WRRPTNVFRAKEDVRPIFWANRPKSYKSRTLSWEQYPHGRWEDSCNPSYGALTDYQCTIT
ESCYDIISGTEIDIAKYSDAYLGLFFSCII
>A0A6G1VSF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIAEFLHQKGDKRGFSFEVLPPLKGNGTAALFRTIDSLKDFDPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHVICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHSNATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMKHLLEKQQLGADYAITQLFYDNEKFYAFVEKARQMGITIPIVPALK
PFAKLSQLTMVPKTFHCDIPEALAQEVLKCKSDEDAKALGIEWTTAQVKDLFDHGYNHIH
FFTVSAVDSVKQIAKILF
>A0A7S2XV05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Attheya septentrionalis|TrEMBL
GGSCCDRAIDLVRLIRTLHGDTFGIAVAGHPEGHPSSSSPEDELDHLQQKIEAGADFIIT
QFFYDANLFLDYVKRCRARGITCPILPGIMPIQSYSSFVRMTKFCNISVPSKVMELLEPI
KHDDEAVKDIGCEISADLCRTILSASPEDGGVDGVHFYTLNLERSVTRI
>A0A840S3N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Inhella inkyongensis|TrEMBL
MRTPVSFEFFPPNTPVGHDKLLNQVVPALAALKPEYFSVTYGAGGATRDKTLATVKAIAA
AGHQAAPHLSCIGATRDSLREILAEYRAQGIRRVVALRGDLPSGTAGLGEFRYAEELVRF
IRETEGPDWQIEVAAYPETHPQCRYAAKDVQHFAAKMKAGADAAITQFFFNPEAYFHFVD
EARRLGVTQAIVPGIMPFHNYHRIAQFAQRDGIDIPRWVALKMEGFMDDTASIRAFGLDV
VTRLCERLIEGGAPGIHFYSLNQSELTLEICRRLGAH
>A0A3D0H1R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacteraceae bacterium|TrEMBL
MSTTTPSKLQKIMAAGHYGVTSECGPPRGTDGHVVEEKARLIGDYVDAINVTDNQTAVVR
MCSLASCIRIKQMGLEPVLQMVTRDRNRIGLQSDILGAASFGINNLLCLTGDHQSFGDHP
NAANVFDLDSTQLVRTATMMRDEGKLLSGFEMKSRPEMFIGAAENPFADPFEIRVMRLAK
KVAAGAQFIQTQCIYNMPKFKLWMQGVVDKGLHEKVCIMAGITPMKGLGMAKYMKNRVPG
MDVPDDLIARLAGIPKEKQAEEGIKIAIEQIEELKQVTGVRGFHIMAIEWEEKVPEIVKA
AGLYPRPKVD
>A7K4E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio antiquarius (strain Ex25)|TrEMBL
MAECHRESKMGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSAKMEETLWNSVHRLKTL
QPKFVSVTYGANSGERDRTHSIIKEIKATTGLVAAPHLTCIDATREELINIADDYWNNGI
ENIVALRGDIPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKR
KVDAGANRAITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKV
PGWMSKQFEGLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLG
VRPRVAVGA
>A0A1H8U3S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus endophyticus|TrEMBL
MTRTVGELLARGGPTWSFEFFPPKTPEGEQQLWTALRELERLQPSFVSVTYGAGGSTREG
TVSVTERIATETTMTPLAHLTAVDHSVTELRHVVSRLAAAGVRNLLALRGDPPGADPQAD
WVAHPEGLSYAAELVELIRSMGDFSVGVAAFPERHPRSPDFETDVEMFVAKCRAGADYAI
TQMFFRTEDYLRLRDRVVARGCDVPIIAGVMPVTNARQITRIVQLSGQAFPAELAARFAE
LDGDRPEDKAAVRAFGVEVATEMCRTLLDEGVPGIHFITMNRSTATREVFANLQPAAAPE
ASLS
>A0A553E5E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. HF-5092|TrEMBL
MKVIDLINNSKDTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNLESDLYWLKKKVEAGAEYAVTQLFYDNKKYFEFVKLAKEAGIQVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEVNRCKNDADAEQVGIEWCIAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A2S7B4E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. populi|TrEMBL
MGPETPSLASTITDAYSLEVSAKDMAGLAAAAPGIMRGSTIAIPYLPSQDNDARLAAARM
VRTLGFQPMPHLSARRIASREELHTFVRRAVEETGVERCLVIAGDPPAPLGPFSDSLSLI
DTGVFERSGIQTIAVAGHPEGHQSMSATDRWEVLERKCRSIAERGMAPLIVTQFAFDADI
VLTWLKALRAHGIEHPVRVGVPGPAGVAVLARYAASCGVGACASMLSKYGISLGKLLGSA
GPDRFVDRLATGLTEAHGEVSMHFYPFGGIAQTVAWVEQYRSRSARHWVG
>A0A1W6E9L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrella sp. ES10-3-2-2|TrEMBL
MTKITDHIRQANGKPIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIEQ
PQPDGTIRKIVTRKRPGTVGICSAIMHRFNVDPVPHVLCGGFSRDETEDFLIDLNYLGID
NVLVLRGDPAKPFKTFKAKENGYSYASELVEQVANMNKGQYLHEEDTAMTPSNFCVGVAA
YPEKHFEAENHDIDFEYLKQKVARGADYIVTQMFFDNARYFDFVTRCREHDIHIPIIPGL
KPISTRKQLEILPRLFHLHMPDDLVNAVAACENDAQARQVGIEWSIQQGRELIAAGAPVL
HFYTMGKGDNVQKIARELF
>A0A6A7WAJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLNKEGQKRGFSFEVLPPLKGNGTAALFRTIDSLKEFDPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTIAIAGAIQNKYDIPVIPHIICSGASKEDIEYELLDLQFLGISN
VLVLRGDKAKEDRQFTPTPNGHAHATDLLEQISQFNEGFFMDGTPIKHPGEKFYCGVACY
PEKHEEAPNLEQDLQHLKEKQDLGASYAVTQLFYDNQKFYDFVERARKMGITMPIIPAIK
PFAKLSQLTMVPKTFHCDIPEELAQEVLKCKTDDDAKALGIEWTTTQVKDLFEHGYSHVH
FFTVSAVESVKQIAKILF
>A0A143B8Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp. DDH964|TrEMBL
MTEISIELVPRNETSLRRELDEVRRHFPAVTRINIPDILRFDLRSWQGCRIAGEYFPRTI
PHLRAIDFDPNSPLPICENLSCREIEAVLVLTGDLPQDMGHKCYRTSCLEMIRRLKRELP
ALTIYAGMDPYRSGIKEEIDYLRAKQDAGAEGFFTQPFFDLRLMEIYQGLLPDCQIYWGV
SPVLTENSQNYWENKNNAVFPPDFRPTLEWNRGFARQALQFARDHDSNLYFMPIRTDIAA
YLDGIL
>M3ILJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida maltosa (strain Xu316)|TrEMBL
MKISQKLSQAHNGSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSSLTNEMVYTSQSTLGLETCMHLTCTNMKVELIDEALEKAYKSGCQNILALRGDPPLD
GSESTGDFKYAKDLIQYIRKKYGDHFNIGVAGYPEGHPEEEDELKTLNYLKEKCDAGADF
IITQMFYDVDNFINWCSKLNKIGVDIPIIPGIMPISTYAAFIRRAKWSEIAIPQHFLDAL
DPIKDDDFLVREKGTELVSEMCTKLLQSGYINHLHFYTMNLEKATVMILEKLNLIEAIKS
HDLVGGSELPWRKSLHPERSKESIRPIFWQHRKYSYISRTATWDEFPNGRWGDSRSPAFG
DIDLCASELLRQSPKKALELWGLPQSLKELSGLVVDYLKGDLKSLPWSDGPVGDDTKVIV
DNLIDLNKHGFFTMNSQPALNAIKSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLNS
VEAFNKSQGDTTSSVISYYAVDKSGNLISNCRDDDINAVTWGVFPGEEILQPTIVEKTSF
LAWKDEVYRLLSEWSKVLSSNLVDADPSKVGGFVELMDKLGDEFVLCNLVNNDFVEGNST
LFNLIKDLHVQELA
>A0A1H1X615|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolymorpha singaporensis|TrEMBL
MASGPAFTAPRPSRTVRELLADGDRSYSFEFFPPKTDQGEQQLWRAIRELEPLAPTFVSV
TYGAGGSTRDRTVRIIARIASDTTLTPVAHLTCVGHSRAELRSVIGAYADAGVNNILALR
GDPEGGPNQPWIRHPEGLDHADELVTLVRELGDFCVGVAAFPEGHPEAISLDSDAEYLAA
KAAAGADFAVTQFFFDADDYFALRDRAERLSCEMPIIPGIMPVTNVRQIQRFAALSGAAF
PPALAERLLAVEDDPAAVRAIGVEVATDLCQKLLDGGAPGLHFYTLNRSTATREIYANVV
GPVVRVP
>A0A1I4B434|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium KH1T2|TrEMBL
MITDILSSKNLMLSCEVFPPKKEEDFTKVFGILDEIASAKPDFISVTYGAGGSNVGKNVE
IASYIQNKCKIESLAHMTSVGYDRAHLAEGLEKLKSEGIVNILALRGDRPKDMTDERYNS
REFEHASDMIPFIKEHGSFCVAGACYPEKHFEAPDELTDLKNLKIKASSGCDFLISQLFF
DNEYFYRLQDNADKIGIKIPMDAGIMPITSAKQLGTTVTLSGTSVPKELSDIIAKYGDDK
EDMKKAGIDYAIRQAIDLADHSVHGIHVYAMNKPELVKAIFNAVR
>A0A385SRM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseolinea soli|TrEMBL
MKVTEHLANANGKTLFTIEILPPLKGENIKNLFKNIDPLMEFKPPFIDVTYHREEYVYKK
KENGLLEKRSTRKRPGTVGICAAIQNHYKVDTVPHIICGGFSREETENALIDLDFLDIDN
VLVLQGDPIKTESRFVPDPDGYMYASELLQQVVKMNQGIYLDDELLHAAPTDFCIGVAGY
PEKHYMAPNLKNDLRYLKLKVDLGAKYVVTQMFFDNEKYFAFVDKCREAGINVPIIPGIK
PLTTKSQLNILSKTFHIDIPEALADAVEDCKDNQAVKEVGIEWTVQQSKELMKKGVPTLH
FYTMGKSDPIYRIAKELF
>A0A7D4XXV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. infantis|TrEMBL
MHSPMFSLEVFHPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGERLVGDFNHASDLV
SYIRSMKPDFTVFGACYPEGHYQSGSLDQDIENLKIKVDAGVTRLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLDALLNRWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFLGTQG
>A0A1B7SPC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ogataea polymorpha|TrEMBL
MKVTNKLLESHREDNAPATFSFEFFTPKTSQGLQNLYDRMDRMYDLNPLFIDITWNAGGR
LSTLTTEMVQTTSTVLGLETCMHLTCTNMKTDLIDQALRSAYESGCQNILALRGDPPLDG
SESTGDFKYAKDLIRYIRKHYGDHFCIGVAAYPEGHPEESDPVKTLKYLKEKQDAGADFI
VTQMFYDTENFINWCDECRKIGITMPIIPGIMPISTYAAFIRRAGWSEITIPKHFSEALE
PIKDDDAKVREVGTKLVIEMCQQLLESKRVNHLHFYTMNLEKSTLMILQGLNLVTKQQLH
DMKQPWRKSLNPNRSKETVRPIFWKNRKFSYISRTANWDEFPNGRWGDSRSPAFASVESC
ESELIRHSPKKALELWGTPNSLKDLAELTTRYINGELSCLPWSDGRISSEIEPTKKQILE
IVKHGILTINSQPSVNGLKSSDKVFGWGPRNGYVYQKQYLEFLVPSSVVSLLIERINEMN
KGADSNILSFYATDKDGHLITNTQDSDIIAVTWGCFPGTEVIQPTIVERISFLAWKDELF
SILDKWVSIFRHEKATQATDFLSSLCDSFTLVTIVDNDYVKSPNARIFKLFQDIDLLA
>A0A2T3GQ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. SEMIA4064|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERASIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRMMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFRDYMKKVRDLGLHEKCFVMVGV
GPLASAKTARWMRSNVPGVHIPDEVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKHEASRTDALVAERLEHIRGGMEENQQQMAEAAA
HHPPHLAH
>A0A7U8K374|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella pinnipedialis (strain NCTC 12890 / BCCN 94-73 / B2/94)|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>T0SZL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteriovorax sp. BSW11_IV|TrEMBL
MKVIEHIDKAGKNPLFSFEIVPPPRGRNVQDIIDIVEGLKPYNPSWVDVTAHSAGAYYNE
RSDGSIERRIYRKRPGTIGICGIIQNRFCIDTVTHLLTQGFTKEETEDALIELNYLGIHN
VLALRGDGLNYSKQISKDRSVNTYAIDLVSQINDIKHGKFLNDITNSRPLDFCVGVAGYP
EKHFEAPNLKMDVHWLKKKVEAGAEYIVTQMFFDTKKYCDFVTLCRSEGITVPIVPGLKV
IKNIKQLTTIPSNFYVDLPDELVDEISSNPNHVEEIGVNWAIKQCDELLKFGVPSLHFYV
MNDTKSVKDVVKKFF
>A0A2K0TS16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma gamsii|TrEMBL
MMDKITDKIAALPADEEYFSLEFFPPKTQMGFSNLRVRLQRMERALRPLFVNVTWGAGGS
TAQKSIELAELCQRELGLTTCLHLTCTNMSQAMVDQALEDARALGIRNILALRGDPPRAE
YRDADEPTGSEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPYL
VDKVQAGADFIMTQLFFDIKAYEKFETTLRDHPSGAFKTIPILPGLMPIQSYAMIKRTAK
LSHAEMPEEIMARLNAVKGDDEKVKMVGVDILSELIEQIREIKSRTPGPRGFHFYTLNLE
KSISFILERTKLIPDVPDDEEAVVDEPVPAAVTGQRSIPRISVNGNVPPRQSRSHSRTAR
RQSSVGSDPFNRVIVGRAAAHPEWEATSTEAGLPAESLNTRANTLAISEGEGALGREATW
DDFPNGRFGDARSPAYGEIDGYGVSIHMSVTQAVSLWGHPKTSSDINDIFVRHIRGEISA
IPWSEEDLLPESNIIKSSLEAMNKKGWWTVASQPAVNGLPSNHATFGWGPASGFVFQKSF
VEFFIPSADWKILYDKLTSEEHEELVCFYASNANGDFVSSDSTGGTGRVTVNASTNAVTW
GVFPGKEIVTPTIIEEVSFRAWSEEAFDIWAEWAKVYGRGSDSEKLLNEIGQDRWLVNII
HHDYVDTEALWRLLTN
>A0A541B3J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas luteoviolacea|TrEMBL
MALSLQEKILDPNQGVYLIGTTPPKLGTDKEQVQTIASKLLNRLHEIEYDGVVIYDIQDE
SSRTEIPRPFPFKQTVDPCEYSQVVSQLSKLDVITYKSVAQRDRGEFTQWLHKTKQDFGL
NNLVLVGSPSSKGDIKLGLPEAYQTLETHQDEFFLGGVTIAERHASKRNEHERLIDKTAQ
GCEFFISQAVYDAQATIDLLTSYARTCRQQGIEPKRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDAENTLKESIKICRENLDLILRSCAQLDVPLGLNIESLTNRKEEIDASISL
YRLLKAIMELQLAEKQIA
>A0A4R7UUL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola oryzae|TrEMBL
MTKVVDRIPGDRPVFSVEFMPPRDDADELRLWNSIRSLEGLDPAFVSVTYGAGGSGRDRT
IRTTGRVVTETTLVSMAHLTAVDHSVAELRNVIGWYASLGIRNVLALRGDPPGDPNGEWV
RHPEGLNYAEELVRLVRSLGDFCVGVSAFPYGHPRSADLDTDTRYLVSKLRAGADFAIAQ
LFFEAEDFLRLRDRVAAAGCETVLLPGVMPLTTPRILSKTVELSGEEVPAALVARMDRFT
GDPKAFREEGMNVTTELCERLLAEGVPSLHFYTFNRAKATKEIVVDRLGLVPGRKAQPVA
>Q03V90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y)|TrEMBL
MTRITDIYKKKSAPVLSFEIFPPKTEDGLHALYKTLQEVNPKETGVDYISVTYGAGGGSN
HKRTKEIAEYIERNCGITALHNLTGINQTPSSLKGNLEKISVAGVENIFALRGDTPTKDY
VNEYYPFAKDLIKEIKKDGRFDIGAAIYPEGHVDNPTTGISVTGVKEKVISGTEFLISQL
FFDNGVFYNMQEALKENYIKVPVSAGILPIISRAQVERITYMIGSSLPARLAKIVHKYED
QPEALQQAGIEYALEQIHDLLDHGVDGIHLYAMNQPNVLKIMLPEINRHIQSKILTL
>A0A255ZA05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium cyanobacteriorum|TrEMBL
MKVTEHITNANGKTLFSFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYEYKE
LPNGLLEKKVVKKRPGTVGICSAIQNRYQVDAIPHILCGGFTREDTENFLIDLDFLGIQN
VVALRGDAVKSEIYFKPEKEGHHFAGELVTQIANLNKGIYLDDDLQNTSATNFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGAEYIVTQMFFDNKKYFDFVAKCRKEGITVPIIPGLK
PISTKKQLNQIPHRFKVDLPDDLIMAVVKAKDNDAVRQVGIEWCIAQSKELVAAGVPSLH
YYSMGKSENIKAVAGAIF
>D6ZJ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobiluncus curtisii (strain ATCC 43063 / DSM 2711 / V125)|TrEMBL
MGKTRTKLVGIIQDMMDLGVRDFLALRGDEAPDSASGAAEPNEFDRAFQLVQLIREVSAD
YLGDAHAVSIAVAAYPAGSIQTRTDAVQALVQKQAAGADFAITQVFYQARDYAELVQSAT
YQGVTIPIVPGIIPFTDMHRLQRLEGLTGVPVPERIKSIANISDPAERILESLGATLNFV
NDLIEANAPGIHFYTFNRPRPVLDLVEHLRSRGFTHVDQEDSQDLLGLMNATMHRISP
>A0A0X3U7J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbulbifer sp. ZGT114|TrEMBL
MTNNTRISFEFFPPKTPEGREKLYKTRETLQEFQPAFFSVTYGAGGTTRETTADIVTNLR
RDGISIAPHLSFGGDNEETVQALLNRYQEAGVDRIVALRGDMPSGMGAVAQLVYANELVA
FIRRHSGDHFHLEVAAYPEIHPEAESYDADIGYLKGKFDAGANSALTQYFYNPDAYFYFL
DQCEKAGIDAPIYPGIMPITNFTNLARFSKNCGAEIPRWLRQRMESFSNPEDIRKLGLEV
VTDLCETLLEGGAPGLHFYTMNQVEPTAEILRSLSLD
>A0A2N1SWV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetae bacterium HGW-Spirochaetae-10|TrEMBL
MHRISDRLKKKQPVFSFEFFPPKNDDGERLLMQTIEDLKALEPDFVSVTYGAGGSTRAKT
REWVRSIQDRYAIPAMAHLTCVGSGRGEIRSILEDLYSDGIRNIMALRGDPPKGETAFVA
PADGFRYANELISFIRSTGLDFCLGAAAYPEVHGEAPSAEEDL
>A0A2M6Y561|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG08_land_8_20_14_0_20_59_10|TrEMBL
MRVTERLKSAKKLFSFEFFPPKTEEDAKKLFESARELKKLGPDFVSITNSSSGSTPYRTV
AMAGVLKAELGLEPVAHLTCVAHTRAEIAGICRRLKELNVENILALRGDIHNIEGLPPKR
DYSYASQLVAELKATGDFSLGGACYPEKHPDAATLEEDIRHLKLKVEAGTEYLITQLFFE
NAHYFKFLDKISAAGINVPVIPGLMPITGYKQLSNFTQMMKVSVPETLRAGLERWADDKE
SLFRFSVDHASAQAAELLAHGAPGLHLYTLNRSRAALAILKNVKGGPG
>A0A2G2MWF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp|TrEMBL
MFKEFCDFLCSQTDEFITVEINPPHGASIAGIIDDIKKHKLHEKVSGFSCTDNPLAKLKM
SSVLSAIKVQQEFGKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKFSDQP
EVKGVVERDSTLLLSIIYRLNNGVDYSNKPLKPAPKPIYPFAVTNSYAKDMTRLKKRMVK
KLDYGARAIITQPVYDLENAKELLVIFEEAKTLSVRDTAKDAQLILGQFPIVSARTATFI
DDKVPGISVPKNIIDAMNLAAMDSVEKEREVGYALSKKIFDDVMTEHGKVHLMTHNRFDL
CAELIG
>A0A0P6K2J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heterocephalus glaber|TrEMBL
MDHGKPRVPAAGPRCPSLGMWASKAGISRYSVPPPISRTWTMVNEARGSGGSSSGSEGSK
DSSRCSTPGLDPERHERLREKMRRRMESGDKWFSLEFFPPRTSEGAANLISMFDQMAAGG
PLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETMLHMTCCQQSPEAITGHLYKAKQ
LGIKSILALRGDPIGDQWEAEEGGFDHATDLVKHIRSEFGDYFDICVAGYPKGHPEAGSF
EEDLRHLKEKVSAGADFIISQLFFEANTFFHFVKACDDIGITCPILPGIFPIQSYSSLRQ
LVKLSKLEVPQEIKDVIEPIKDNDAAICNYGIELAVSLSRELLVSGLVPGLHFYTLNRKM
ATTSVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQDWNEFPNG
RWGNSSSPAFGELKNYYLFYLKSKSPRQELLKMWGEELRSEESVFEVFAHYISGEPNRHG
YKVTCLPWNDEPLAAETSLMKKQLLRVNRLGILTVNSQPNVNGRPSSDPIVGWGPSGGYV
FQKAYLEFFTSRETVEALLQVMKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGR
EIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSRMIIQYIHDNYFLVNLVDNEFP
QDSCLWQVVEDAFELLNRPAGLKGEAEAQ
>A0A809FNG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis subsp. subtilis|TrEMBL
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDVYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLVPIKEKEVKTRAKEFIS
VHHERTEPGLDEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALIKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNEIKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMARAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>A0A5B8RU30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp. NLF-7-7|TrEMBL
MAVPLSFEFFPPKTPEGVNKLRAVRQQLYALAPEFCSVTYGAGGSTQAGTFATVQEILGE
GVAAASHFSCIGATRAGVRAQLAQLRAMGVKRLIALRGDLPSGYGTGGEFQYASDLVAFI
RAETGRDFQIEVAAYPEMHPQARSPESDLKAFAAKVQAGADSAITQYFFNADAYFRFVDE
VRAAGLQLPVVPGIMPILGSTQLLRFSDACGAEVPRWLRLRLQGLGDDVASIRAFGLDVV
ARLCERLVAGGAPALHFYTMNQSAATLELCRRLGLGRG
>V5DSA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloglobulus morosus KoM1|TrEMBL
MQSQKNHPQPFSFEFYPPKTEEGAANLQLVHTKLAEQNPEFFSVTFGAGGSTRDKTFDTV
VDIQQKGIAAAPHLSCVASTKENIRSILKSYQEHGISKIVALRGDLPSGMMSAGEFRYAN
ELVAFIRQETGDDFEIHVAAYPEAHPQASSAAEDFKNFKRKVEAGADAAITQYFYNAEAY
FYFLDLCEKNGITIPIVPGIMPITQYAQLFRFSEMCGADIPRWLRKRLEGFGDDRTSIQA
FGLDVVSDLCQRLLDGGAPGLHFYTMNQSAPTLAILGNLRQ
>A0A5P6NFA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania flava|TrEMBL
MREAQRALETPLFSGLPGDIEVSFEFFPPKNEKMGETLWRSVETLAPLGPRFASVTYGAG
GSTRERTHQQVVRIQNEANIPAAAHLTCVEATRDQVDEVARHYWDEGIRHIVALRGDAPD
GQGTYRPHPDGYGNAVELIAGLKRVADFEISVAAYPEVHPDSPDRQADLDNLKAKFDAGA
TRAITQFFFDPECFFDFRDRAAVAGIEGEIVPGIMPVLSFAAVQRMSGLCGTAIPDWMEG
LFDGLDDRPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKVA
A
>A0A1M3F8K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. 73-92|TrEMBL
MNEPAVGTATAGPPRAAADRPTLSFELFPPRDIDNAPRTWETVRALEAVHPDFVSVTYGA
SGRTRTTSRALVSRILRETTLTPIAHLTCVGTSREEVTTIVGEFLDEGVRSFLALRGDPP
SDADSWHPHPQGVPTAAGLVALLREIEANRCATSSAQAVRARVKPLSVAVAAFPRGNAVT
GSTRAQDIQALLDKQRAGADFAITQVFYDAAAYLELVAEARDKGVTIPIIPGLLATTDPA
RLLRTQELTGVPVPRELLELLGSADDEAERHRRGIRFAADLVAGVLDGGAPGIHLYTFNR
HEAALDLLDAADLTARPTPRNP
>A0A3R7RPK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaera sp. TMED9|TrEMBL
MAETPAEGSPTISFEFFPPATPAGWTALDRRIGELVPLEPSFVSVTYGAAGTTRDRTHDL
VERLLKETKLRPVPHLTCVGHRRDEIDRILERYASAGVDTILALRGDAPTEGSEPVDGDF
DFAADLVSHIRSFGERHGHHFRIGVAGFPEGHPDTPNTLECMDHLQAKVDSGADWICTQL
FFDNHAFHDWKARCRLVGIEIPIIAGIMPISTRKSIRRMAGLAAGTVFPATLQRSLARAA
EGDDEAIAEIGIHWATEQCRDLLDRKVDGIHFYTLNKSDATLRIHRSLGVRTSRELQRDG
GGIG
>A0A2N2CKY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-17|TrEMBL
LGIENLLLLTGDYTTLGDHPQAKPVFDLDSVSLIHAVKRMEEGFDIAGNAIDGAPPKFAK
GAVVSPCSDSVDVQLAKMEAKVKAGCEYFQTQGVYEPEKFIKFMEQAKQFGVPVQLGLII
PKNVGMCRYMNANVAGVHVPDDMIKELQADKEKTKAGDTGVEICARLIKECKDYAQGVHI
MSLGWENRIPEILDMAGIAPITPVV
>A0A0F8QZU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. 1.H.A.2.2|TrEMBL
MLFNFREKLNSRKFLVTVEVSPPKGTRFSAPLEDACQLKGVADALNVTDNQCSIMHMSSL
AFSKLLLDQGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDHPTCGDHPGSKP
VYDLDSVQLIELVRKLDSGIDFAGKSLDGGTSFCAGAVSGIDPKNTLQLIKLEKKVKCGA
DFIQTQAVYDVGMFEEFIEAVNHLEVPVIAGLIPLKSLSMAEYMNKNISGIHVPEEIMLR
MKDASSPIEEGLSIASDTIKELTKLSRGVHIMPIGSHKNTPRLLSMAGISGK
>A0A7W6ZUK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leucaenae|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLQEKCFIMVGV
GPLASAKTARWMRSNVPGVHIPDAVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKHESSRTDALVAERLEHIRGGMEENQQQMAEAAA
HHPPHLAH
>Q8EA55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella oneidensis (strain MR-1)|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETNLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPSWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPKAV
>A0A420D212|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. AG855|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKVF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMAKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDHVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGVLKGRQPWKREHARADDIAALRMREIGADPVQDQQEMAAKAA
QPQPH
>U2QAV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia wadei (strain F0279)|TrEMBL
MRIKDLFEKKEHLISFEIFPPNKNFSVEKLKDVTDELVQYKPDFISVTYGAGGKTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEINDYLQEAKKCNIKNILALRGDVPQGETEEIYN
RGDYKYASELISDLRKNSEFNDFSIGGAFYPETHYENNDLVDLFHLKNKVEAGTDFLASQ
MFFDNDIFIKFKEQAEKLDIKVPLIAGIMPVTNAKQIKRIIELSKCSVPEKLDKLLGKYG
DNPESMKKAGIMYASEQIIELLAYGIRGIHIYTMNKPEIAKEIVKNIEFAR
>A0A0Q0I2Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. theae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKNAGIKRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A328YTF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax anthurii|TrEMBL
MSLSTALPVSFEFFPPKTPEGAEKLRSVRQQLYARRPEFCSVTYGAGGSTQEGTFGTVRE
ILAEGVDAASHFSCIGATRASVRGQLATLKAMGVRRLVALRGDLPSGYGVGGEFQYASDL
VAFIRAETGEDFHIEVAAYPEVHPQARSPEADLQAFAAKVRAGAHSAITQYFFNADAYWR
FVGDVRRLGLDVPVVPGIMPIMGSTQLMRFSDACGAEIPRWIRLRLQGFGDDAASIRAFG
LDVVTALCEQLRAGGVPGLHFYTMNQSAATLEICRRLGL
>A0A4V1MRX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter aloeverae|TrEMBL
MTDTKTPALSLEFFPPRDIAAQERLVRAAKQMLAMHPRYVSVTFGAGGSTREGTAGTVRI
MRNLGVAAAPHLSCVGATREDLRGILRAYREEGVKQVVALRGDLPSGMGGDAGELRYARD
LVAFIREETGDWFHIEVAAYPETHPQAESPSVDLDHFVDKVQAGADSAITQYFFNPDAYF
DFVDRARAKGVTVPIVPGIMPITNHSQLVRFSQMCGAEIPRWIRMRLAEFGDDKASIRSF
GVDVVSDLCRRLLDQGAPGLHFYTLNNADAPMAIWKNLDL
>A0A414V3C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARASGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A2S8ZM53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. MYb64|TrEMBL
MSFDAPPFAPAGAVVPRVPISFELYPPRTTAPIEALHETIQQLASAAPRFISVTYGAGGS
VGGRSLDVLRYIREHTSVEPLAHLTCVGNTYAGASRLIREFLDAGILSFLALRGDPPLDE
SQPFLGDLESSAQLVQLIDRAQAERAPYQERPIPGVPGAVQVTPRRKVNIAVAAYPNGHP
RSTYRNQDIDALLAKQAAGATLAITQLFFHPDDYFAFVERARRAGVTIPILPGIMPITSP
ARLRRVLELSGEELPAELSIDLEVEPTAEGRTEIGVAHAAELVRELVDGGAPGIHLYAFN
QHRTVLDVLTAAGVLPEGGATSPVGGALQLAETSGAH
>A0A1B7K887|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyvera georgiana ATCC 51603|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAVPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A3B7M590|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WCHAc010052|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLDDFN
GKGTPVAPHLSCIGDSKQRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQRFCDKARAGANAALTQFFFNPDAYFYFV
DRIQKEGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A0E2P0Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNJC391B00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETGAA
GSAAA
>A0A8C9BTN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocoena sinus|TrEMBL
MDRPKPRVLPAGHCCPSLGMRAWEAGSARFSVPPSISRSSAMVNEPRGHGGPSPRWEGSS
SGSESSKDSSRCSTPVLDPERHERLREKMKRRVESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKRLGLKNILALRGDPTGDQWEEEDGGFNYAVDLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEAGLKHLKEKVAAGADFVITQLFFEADTFFRFVRACSEIGITCPILPGIFPIQ
GYRSLRQLVKLSKLEVPQQIKDVNRALSLCRELLASGSVPGLHFYTLNREVGPPQRRPLP
WAISAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYL
KSKSPKEELLKMWGEELTSEESVFEVFAHYLSGGAEPERDPAWLTLPSLMKGGAAAAWNR
RGILTINSQPNINGKPSSDPVVGWGPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRV
NYHIVDVKGDNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWG
KLYEEESPSRTIIQHIHDSYFLVNLVDNEFPLDSCLWQVVEDTFELLSGPPQGKRETEAP
>A0A6C7ARI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium (strain ATCC 68169 / UK-1)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7V4Q5H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium|TrEMBL
AQTQPIYDLERLKQMLEQTGELGIPILPGVLPLVSGRNADFLHNEVPGIVIPDQIRLRMA
GRSGDDGVREGLEIAREFIEGAIDLVGGFYLIPPFGKYQVAVELVKFIKAHRAG
>A0A7L2XNY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erpornis zantholeuca|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVFAGADFIITQLFFQPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCQELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A1Q7J0Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium 13_1_40CM_4_69_8|TrEMBL
MSEVTLRKLLDDGRVHVLDGAMGTMLYAKGFFLNVCYDELSLKQPKLVQEVHEAYVRAGA
EILETNTFGANPVKLRSYGLADDTEKINQAAAELARAAAAGHASVVGAIGPLGVRIEPFG
ALSREEACAHFGRQVDGLLAGGVDGFILETFSDTDEIHAALRAVRSRSDLPVIAQMTIGD
DGLTHYGTGPETFAKQLTEWGADVIGVNCSVGPAGVLEAVEKMVKVTDRPISGVPNAGLP
RDVGDRKIYLASPEYMASYARRMIEAGARLVGGCCGTTPEHIKKIRDYVASVVPRHPPVV
VSRAEIRAPAGAEAVPLAQRSRWGAKIARGELVTSVEIVPPKGVDATPMLEQCRALKAAG
VDAVNVPDGPRAQSRMGVLPSAILIEREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLR
NILIITGDPPKMGPYPEATAVFDIDSIGLTNLVFRLNHGLDPGNNPIGAPTRWAIGVGVN
PGAVDLDRELSRFAWKVDAGAEFAVTQPVFDPAQLEAFLARVGQFKIPIVAGIWPLISLR
NAEFLANEVPGVSVPESVLARMRQAQEKGKEAALAEGVQIAREMFQQVKRSVQGVQVSAP
FGRVEVALEVFG
>A0A2R8AQU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoprimorskyibacter insulae|TrEMBL
MTTPEISFEFFPPKNIEGTFRLWDTVQVLAPMAPRFVSVTYGAGGTTRELTRDVVATLHK
HSGLRTAAHLTCVNATREETLAIARDFAAAGVTDIVALRGDPPKGQDRFTPTPDGFQNSC
ELIEALKATGDFTIRVGAYPDKHPEATTETADVEYLKRKFDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGILPIENWKGARRFAESCGTKIPAWVIDAFEKAERDGRTDLLAT
AICSELCSDLMDGGVDKLHFYTLNRPELTRDVCHAIGVTPSVKLENVA
>A0A373WQY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF17-6|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNQHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A0B2C247|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceibacterium mercuriale|TrEMBL
MATDPVSYAAIHPDWERARTNMVDGYSLEMTARELDALQAAAPFIRPHTQIAVTFLPGEA
LEQRVAAARLVRQLGFEPIIHLSARRLTSEAELDTYLARVAAEAGLKRVFVIAGDPSQAE
GPFEDSMQVIESGLLEKHGITIVGIGGHPEGHPAVDREQLWLWMERKVAALRARGILPLV
VTQFGFDDDAIVDWVATLRARGIDVPVRLGVPGPAGIKRLLGFARRCGVGASATVLKKYG
ISLGSLLGSAGPDRLVESLERKLGPDHGRVRLHFYPFGALTASADWINDYAARH
>A0A5P8JUC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus manihotivorans|TrEMBL
MKVNQLFNKHQVISFEVFPPRQKSPSIDFSRIYGTMDALSQLDPDFVSVTFGAGGSKRQA
GTLEIASLIKSEYGIEPVAHLPASQLTGAEVDELLDQFATHGIQNILALRGDIPKSGRVA
NDFVHANDLVAHICASGHDFNVIGACYPECHPEASDLNADIAHLKLKVDAGANQLISQLF
FDNQVFYDFVAKCRAAGITVPIEAGIMPVLNQHQIQRMAEMSGVSLPEKFTAMMARYEGN
PIAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVAARIVQATRSLVRA
>A0A3M4D6A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. lachrymans|TrEMBL
MGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEEVITQM
CERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A2S7Y1Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beauveria bassiana|TrEMBL
MHIKDLLAETKRSGKPSFSFEYFPPKTAQGVQNLYDRVDRMYNFGPQFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGMEKVNDALRKAYKAGCTNILALRGDPPRAQEK
WTATEDGFQYACDLVRHIRATYGDHFDIGVAGYPEGCDDNDNEDELIEHLKYKVDLGGTF
IVTQMFYDVENFIRWVGKVRAAGITVPILPGIMPIATYASFLRRCKHTGCKIPQSWLDLL
EPVKNDDVAVREVGKKLVVDMCRKLMAADIHHMHFYTMNLAQATRMVLEELNWTPSAERP
LQQALPWKPSKGFGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRLKWGEPKSLRDIANTFVRYLNQEIDSLPWSEAPLTSEADSIKPALIE
LNQRGFLTINSQPAVDGVKSSHPVHGWGPANGYVYQKGYIELLVSPKIVDQVIQLVNTNP
SLTYYAVTKNGNLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFDAKSPSRVLVESVMDNWYLLNIVNNDFHDNTTIFELFRDLKVDGLDTPIAVEAEAT
VAAEAEKPAAAQAEAVA
>A0A520XC99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Acidulodesulfobacterium acidiphilum|TrEMBL
MPNKLKENLENNVFVYTSELSPERGADLSKMKDNYGLLKDIITAFNITDNQGANMKMSSL
AGSIYIKQNGGEPIFQQTCRDRNRMALESDLLGAAAFGVQNVLALTGDYISFGDHKHAKA
VYDIDSVNLIEIIKGLNAGTDMNGNKLNGRTNFYIGAAVNPESEPLEPQLIKFEKKISAG
CDFFQTQAVFDVNKYAKFYDFYKSFKEIKIIAGIYILKSAKTARYMNKFIPGIYITDEII
NELENASDPLKKGIEIAARTAKELKPLVHGIHVMAFGIEDKIPLFLRNMLDI
>A0A1Y1RAR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacteraceae bacterium 4484_4|TrEMBL
MFENFMTKLQNGPFLTLETTPRHSPQFDPIVERIRELGLHKRVDGFSVTDSPLAKLKYSA
LFAALKLQTAFKKPVIATMSMRDRNKIGLQSSLLGANDFDIRAILALTGDPASMSDQPQT
KGVFEGNSTLLLEIIKCFNAGIDYAGKPLDIKPKPIYPFSVSNAFAKNPKNLQKKMRTKL
EGGTKAIITQPVYSLENAKMLLELFEKAKIESGTKVDAQLIIGFFPIVKLRTAQFLSSHV
PGVEVPKIWGDRLYQAKKISEEEQERVGLELSVEAFRSIWKMHPKMHLMTANNFSLAREI
IETI
>A0A4Q4CYL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacteraceae bacterium|TrEMBL
MDQTLPGTLQRWLTGPRFGGLPNFAELPVPQLSFEFFPPKNDALEAQLWSCIRRLEPLAP
QFVSVTYGAGGTTQARTHATVARLVRETSLTPAAHLTCVGASRAEVDEVARSYWDAGVRH
IVALRGDAPAGAERYEPHPDGYAYAADLVAGLAKVAPFEISVAAYPETHPTALNADHDLD
NLKRKIDAGATRAITQYFFDTDVYLRFLDRCAAAGITTPIVPGIMPVSNFTQMKKFSAMC
GAGVPDWMGRLFEGLDDDPETRRMVSVVLAAEQVRLLQANGVDEFHFYTLNRPDLVYAIA
HILGARPGLGQKA
>A0A3A6N6T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dethiobacter sp|TrEMBL
MLSNFKEALNSGKFVVTSEIGPPKGTNIQQMLHHIDLLKTRVDALNVTDHQSSVMRFPSI
GGCLAIKEKGGEPILQVTCRDRNRLALQAELLLAYTRNVRNVLCLTGDAVPVGDHKEAKG
IFDLDSVQLLRTIRQMETGKDSGGNDLDGAVEFCAGAIVTPEANPIEPQLIKFEKKVEAG
AEFFQTQAIYDLDKFAKSMQYARQFPVKILAGIVLLSSARMAKYMTDNVPGINVPQDLID
ELAGAPKSGALKKGIEIAGRMVAALKKDSICDGVHIMAINKEEVVPEILAIAEL
>A0A7Y3L9J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTSVVGKSVRIDQLFAGGPTRSFEFFPPKSSDELVTLSSTLHDLEALSPSFVSVTYRGGR
ESRQRTFDLVTDIQRDGHLVTMAHLICVGHRRAEMREILENYQSAGVANVMALGGDIPEE
PDLVASDFTHAIDLVELALEIGNFSIGVAAHPLGHPRSVDLASDRRHLAAKLELAHFAVT
QFFFELRDWTNLVGELDELGVTKPVLPGIMPVTTLSGVARMAHMGAAVPPSLIERLENAQ
YAGGASAVRAEGVAAAIELCQQLLDAGAPGLHFYTLNRSTATREIHEALYGSDGVRRP
>A0A7K1Z603|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTYEVIPLKSLPEAIQQLPANARVSVTASPVKPLEDTLDVCAELLDLGHRPIPHIAARKV
TDAAHLRSLAARIKQLELSEIFCIAGDAQDAGEYPDAMSLLRPLLDITAGDISAVGVSSY
PDGHAFIDDSDLHRALIDKQELFREAEIKGHASTQMCFSTDTIVSWLTSQRGEGLTMPVH
LGVAGVVDRTKLIRMGMRLGVGASLRYVQKNRTGLLKLFSSVGYNPSDVIDPLAAEFDSL
GIEGLHMFTFNQVAATQRWQQAKLR
>A0A6J3JPI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sapajus apella|TrEMBL
MMIASTAVNYCGLETILHMTCCHQRLEEITGHLHKAKQLGLKNILALRGDPTGDQWEEEE
GGFNHAVDLVKHIRSEFGDYFDICVAGYPKGHPDAESFEADVKHLKEKVSAGADFIITQL
FFEADTFFRFVKACTDIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKD
NDAAIRNYGIELAVRLCRELLASGLVPGLHFYTLNREVATTEVLKHLGLWTEDPRRPLPW
ALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKNYYLFYLK
SKSPRDELLKMWGEELASEESVFEVFVHYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKE
ELLRVNRQGVLTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVL
KKYELRVNYHLVNVKGENITNAPGLQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFA
LWIEQWGKLYEEESPSRAIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQH
EREAEAP
>A0A7C7XUY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIKKAIGKTQFTFEILPPIKGHSVQSIFDNVDPLMEFNPPFIDVTYHREEHIYND
LGNGLLQKKVVRKRPGTVGICAALQNKYNVDAVPHILCGGFSKEITENLLIDLDFLGINN
VVALRGDAIKSETYFTPNKEGHSYASELVNQVSDLNKGKYLEELEISSKTDFCIGIAGYP
EKHIEAPSLESDIHFLKEKVKLGAEYIVTQMFFDNKKFFEFQDICKKEGINVPIIPGLKP
ISTRKQLNILPHRFHCDLPVTLIKEVIKCKDNSQVKQVGIEWCIQQSKELMKAGVPFLHY
YSMGKALNIKKIASEIF
>A0A136Q564|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Christensenella minuta|TrEMBL
MDLFQNNDYLLFDGAMGTYLEEKYEGGVNRCELNNIRHPERVVAAHREYIAAGARAIKTN
TFSANTFSLGEDLETVLRIIDAGCACAREAAEEDTLVFASMGPILHDDQKRCDSERRQAI
DRFLANGVDCFLFETFADPSVLVRAARYVKERCPDAYVICECTVAPDGYTQSGISAQGAI
DMMKDVYAIDAYGFNCTCGPMHMAHIAKTTNFYGRTVSIMPNAGYPTMEGGRTVFKSTPA
YFAGQLRKSRQAGARILGGCCGTTPAHIRAAKEALAQADHTPAAAGAKAKVHITCGEEAP
RTFRGKPVAVELDSPLDADGTFFVEAAQEIKAAGADYITVADCPVGRARADSSMLAAMLK
SQYGIETLPHLTCRDRNLNASKALLLGLSLQGVRNVLVVTGDPIPNNRRGEIKSVFQFNS
VLYADFIRDLNRTVFAGKPFRIMGALNVNAANFDAELKKAHKKEKAGVTCFLTQPVYEQR
AAENLARAKRELSSELWAGVMPVVSYKNACFINNELAGIEIPADLCERFRHADREQAADI
AVETALSSVEMVEDTADGYYVITPLRRADIVCRIVKELKA
>A0A6I9NTW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Notothenia coriiceps|TrEMBL
MVNQVQRGDGSWQSCKSDSSGASNSGGESSKESSRCSTPVLDADRLDRLRDKMRKRTESG
DCWFSLEFFPPRTASGAVNLISRFDRMGTGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLDSILHLTCCNQTKENITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNHAI
DLVKHIRSEFEDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPKEITEVIEPIKDNDAAIRN
YGIQQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRTLGPLSPSQSSF
PVTVLCPCENPLSLRQSVLCPRVSQSSVPSQSSVLESVLCPQVGLLSPRRSSVPETVLCP
GDGPLSPSPRDGPSSPRRSSIPETALCPRDSPLSLSQSSVPETRQSSVPESVLCPRVSPL
SPSQSSVPETVLCPCDSPLSPSQSSVPESVSPLSRVKCLPWNDEPLAPETNLLKDELEKV
NRRGVLTINSQPNINGKPSTDPVAGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEP
RVNYHIVNVLGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQ
WANLYEEESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWQVIDDMFELLDAPPETHHGGE
VSE
>A0A7Y3FAV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTDHIKQAKGKTLFSFEIIPPRKGKNIQELYNNIDPLMEFEPPFIDVTTSREEYIYID
RDGLFDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEQKYFEASKGGHNYAIELVEQVKNLNDGKYLHDVVETDDKADFCIGVAGYP
EKHIEAPSLQSDLKRLKEKVDAGADYVVTQMFFDNIKYFEFVDLAKQMGINVPIIPGIKP
IAIKRHLQLLPKVFKIDIPEDLIFAVEKCKNNKQVRQVGVEWATQQSKELQKAGVPVLHF
YSMGKSDNIKAIASKLF
>A0A1H6J5E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopenitus malekzadehii|TrEMBL
MSLETPSTTNDGAATLLADPRFELMPFDSFGEQMGHLPDGAAIAVTTSPTLGIDATVEWT
ETASEAGYEVIPHVAARYVRDRDHLDAIAGRLREAGVTDVFVPGGDREEPAGEFESAHDL
LVALEDLEYEFEEVGITGYPEGHDFLSEETLAEAMERKEPYASYLVTQLCYDPETILEWI
DTVRDRGVDLPVEVGIPGVMNYQRLLGISKKVGVGDSVRFLRKTSGVLGFIKELVGSRGQ
YAPDELIDGLAPHAADPHYDIRGVHIYTFNQVPDTESWRLGRLEN
>A0A1H8CG09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lihuaxuella thermophila|TrEMBL
MSKKPLKEYLAESLIVGDGAMATYLFQQGVSIGHCNEELVLTSPSLIAEVHRAYYEAGAR
LIETNTYGANRERLARYGLESKVIRINREAVKVARESVGEDAYVAGSIGSICAGRVAAFD
EEEYRDMYEEQATALLHAGVDAIILETFLDVKELLIAVKAIRPLTRVPLIAQLSTIEVGR
TRDAYSLTEAFRLLAEHGADGVGINCRLGPVEILRSLEKTVVPENLILSAFPNAGRLGMS
DGELKYKSIPGYFEETADLLVEQGVRLLGGCCGTTPEHIRRVAAALSGKKPVKRVNPELC
RIEAVTTEPVEIVRTRPTVVEKVKNERTIICEFDTPKDLEISGFLTGAQRLQEAGVDTIT
MADNSLATARMSNLALGAILKSQFGIDPLVHVACRDRNLLGQQSHLMGLHALGIDQILVI
TGDPTRMGDLPGASSIYDVTSFELIRMVKQLNDGISFSGKRLKQKARFVVGTAFNPHVRQ
LEAAVRRLEKKVAAGADFVMTQPVYDEQGILNVYEATKHVGIPVFIGIMPLTGYRNALFL
HNEVPGIKIPEHVLKRMEAVQEDREAGRREGVEIAKELLDVAMEKFRGIYLITPFSFWKM
TEELALYIRQKDRRRVAVEA
>A0A6S6XJG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcaceae bacterium BL-4|TrEMBL
MKIIDLLNSGHTTISCELFPPKKGEDLPQAQEVVKQIAALHPAFMSVTYGAGGGTSATTV
RIAQEVQKSHVPALAHLTCVSSTRDEISERLSELKKAGIENILALRGDIPEGKDFPSPNQ
YHYASELIREIKARGDFCIGGACYPEGHVECAHKTEDIRHLHEKVEAGCDFLTSQMFFDN
DLFYNFMFRALAGGVNVPIIAGIMPVTNAKQITRICSLSGTILPQRFKAIADRFGSDPKA
MKQAGIAYATEQIINLISNGVPHIHIYTMNKPDIAAAIFHNLSDVISCHGN
>A0A838F9W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagales bacterium|TrEMBL
MKVTEYISQAKGTLVSFEILPPMKGKSIQSIYDTLDPLMEFKPPFINVTYHRSEYIYKRN
SQGLFEKTVIRKRPGTVGICAAIVNRYKVDAVPHIVCGGFTVEETEDALIDLAFLGINNL
LVIRGDPNKSESSFEAEPGGHRNAIDLLKQAVRMNEGIFLQEDITDVVPTDFCIGVAGYP
EKHYEAPNMKMDLKYLKDKVEAGAKYIITQMFFDNSKYFEFVKCCRESGITVPILPGIKP
ITNRKHINTLPRMFHVEIPEDLANELQHVTSDEAARKIGTNWCIEQCRDLISHNVPLIHF
YTMSNPGPVKAVVSKVF
>A0A7V5VL95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MTREAFRERLAQGALVADGALGTMLALRGVPQPYELANLTHPEVVRALHREYYEAGARLI
ETNTYYANRVRLLNLPERASEAPVVSSFLEQFGSPAELVERINIEAVRLARESVGADALV
FGAVGPVGKPLEPMGEVRLEEAEQAFEEQIRALLKGGVDGLILETFIDMQELALAVQVAR
RLAPNLPIIASKGFVEDGETLMEGLPERFAQQMQQLDVDAVGGNCIVGPQRMLDIVRMMA
GATEIPISSMPTPGLPQLVRGQVVYDIHPDYFGKYAARLVEAGANIVGGCCGTTPDHTRA
IAQHVQGLKPKRAAVSPVRTRERKPQEELPTAEPSRLSQLLGKERVITVELDLPRGLKIQ
KVIDGARLLKEHGVHLIDISDGARARLRMNVIATSHIVQREAGIEVMMHFACRDRNLLAI
QSDLLGAHALGIRNVLAITGDPAQIGDYPTATSVFDVDAVGLVRILRRFNEGRDLAGNSI
GVKANFTIAAAYNPLAPDLDAENDRLRRKIDEGAHLIYTQPLFEMPLVERTAELLQRLDT
PWFVGVLPLRSARHAEFMHNEVPGIRIPEPVLKRMTEAPEDSALQVGLEIAQAFVREAAP
YAQGIYLMPPAGNAQIALQVIQALS
>A0A366I680|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brenneria salicis ATCC 15712 = DSM 30166|TrEMBL
MIITVTVNGVAGMSFFHANQREALNQSLAELQGQINVSFEFFPPRTSDMEDTLWNSIDRL
SNLKPKFVSVTYGANSGERDRTHSIIKSIKERTGLEAAPHLTCIDASREQLREIAQDYWQ
SGIRHIVALRGDLSPGGGKPEMYAADLVTLLREVGDFDISVAAYPEVHPEAKSAQADLIN
LKHKIDAGANRAITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATMTN
VRVPNWMTAMFEGLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICH
TLGVRPAVTL
>A0A2U0S9R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas pokkalii|TrEMBL
MAPPLFADVAGDVAVSFEFFPPKTEKMEETLWASIETLSPLGPRFVSVTYGAGGTTRERT
HATVSKIARETPLAAAAHLTCVEATREEIDQIAEEYWAAGVRHIVALRGDPPRAGEKYRT
HPGGYENAADLVAGLRRLHPFEISVSAYPECHPDSPSPEADLDNLKRKIDAGANRAITQF
FFEAETFLRFRDRAAAAGIDAEIVPGIMPVMNYASVVKMSAMCGTDVPAWMEKAFEGLDD
HPAARQLVSATLAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGLRPRQQAAVAAA
>A0A349NME8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIEQANGKTQFSFEILPPLKGQNIQSIFDGIDPLMEFNPPFIDVTYHREEYVYKE
LENGFLQKQVVRKRPGTVGICAAIQNKYDVDAIPHILCGGFSKEDTENFLIDLGFLGIDN
VMALRGDAVKSETYFSPEKDGHSYASQLVAQISDLNNGKYL
>A0A2E9PZQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MKSTQLRLLDGMTYELIPLKNVHEQGEFLPESSTISITCSPAKDIEATLELCENFLAKGH
TTIPHFAARMVESEEHVNQIVKRVEALGIEKVFIIGGDADQRGPFTDAPGLLRSFLDKNP
SIKTVGIGSYPDGHPAIPESALAESLIKKQEMILESNLNGYMATQMCFEANTISNWLKNC
RNAGVTLPCHLGLPGAVDMKKLINISLRLGVGVSSRYLKKNRKSVFKLLSPRGYNPNKLI
TPISDDAEELDIAGIHCFTFNAVQSTEAWRAKAMSRLT
>A0A2E0RRN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTTYSFEVFPPKTDAGLVQLAEAVAELEQLRPSFVSITYGAGGSSRDRSFETISTVARHG
STMAAHLTCVGQSRADLHDVIDRYLALGVSHVVALRGDPPEGIDAPYRPHPDGYTSTAEL
VAAAKDRGIEHVSVSGYPEKHPQSPSADHDMQILAEKAAAGADSAITQMCFDTDATLRWI
DRVRAADIDIDIAPGIFPIHSFPAVARFAARCGASMPTEVAERFAGLDDDPDTTAKVGAE
LAAQQIHRLREHGVRHVHLYTLNRAPLARAVTEQL
>A0A539DRA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MARIADLLAAGPTYSFEFFPPKNEAGWLSLGRTIAELEDLEPSFVSVTYGAGGSTRTRTA
DLVSWVKRQTPIPPMAHLTCHGHSRHEIADILIDYRAEGVENILALGGDPPADGSPAPGS
DYRYSSELVDDIRSTGAFSIGVAAHPELHPRSPDRDSDRRHLASKLRDADFAITQFFFEV
DHYLALVDDMGAHGVDKPIVAGIMPVTNLAQVSRMAHMSGAEVPRWLVDRVAKAGDDADD
AARIGVEIATELCARLIEAGAPGLHFYTLNRSSAVRSIYTELGLTPSP
>A4XPF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mendocina (strain ymp)|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEVAAYPEMHPQARNFESDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLGLKR
>A0A2G2GMT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robiginitomaculum sp|TrEMBL
MTQAIARGNSGNLRPIEVSFEFFPPKNQAMEDRLWQSVRKLAPLRPNFMSVTYGAGGSTR
DRTRKTVVQMAQETGIEVAAHLTCVEASAKEIDDVVKTYKSAGINHIVALRGDPTSGIDG
KYQPTADGYSYASDLVAALKKSPDTIVSVAAYPERHPESSNWQVEMDNLKRKVDAGADQA
ITQFGFEPGQMIDFLDRVRGAGINIPIVPGIMLQPNFDGLVRMSKMCGASIPKWMFNLFE
GTKDDLVTRQLLTANIAAEYCTALQAAGFRRFHFYTLNNADFAYATCRVLGLKPHTGDAK
>A0A2T2SBV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QH_1_61_8|TrEMBL
MKVTEHLDQAPEPLISYEIIPPKRGGSAEQILRVVEELMPYDPPFIDVTSHSAEVNYEKQ
DDGTWKRRVKRKRPGTIGLCAAIEARFDIDTVPHLLCRGFTREETEDALIELSYLGIDNV
LAIRGDDTGYEKPAQGDRSRNEHAVDLVRQIDDMNRGEYLEDLIDAESTDFCIGVGGYPE
THFEAPNLTWDIMRTKQKVEAGADYIVTQMFFDNEYFFDFVEQCRDVGIEVPIIPGIKIL
KRKRPLRSLPKYFHTEIPEELAAEVDAADPDDVEDIGVEWAIRQTRELMDAGGPCLHFYI
MSSAKTVKKVVEPLHEMA
>A0A151E633|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon SM1-50|TrEMBL
MNYRSNLEKVLTEGHFVVTAEIGPPKGTDANKIREKAKLMKDSADAFNITDNQTAVVRLS
SLAGSVILLHMDMEPIMQITCRDRNRIGLQSDVLGAAALGVRNMLCLTGDHQKFGNHPAA
KGVFDVDSIQLLQIIKNMRDEGIFQSGDRLLSGKPYVFLGAAANPYADPFEFQVDRLRKK
IDAGAEFIQTQSVYKIDKFSEWMDDVRAQGLDTKVHILAGITPLKSVKMTERMKFHVPGT
DVPNSVYLRMKKASDPAKEGYAIAVETIHQLKKIKGIHGIHITALFWEEIIPLLVKDAGL
HV
>A0A1G8C347|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteribacillus bidgolensis|TrEMBL
MEFLNKLQQNMLVGDGAMGTYLYDKGITGCFEMLNLSNPNTIKAVHKEYVKAGSDVIQSN
TYAANKIKLEKYELSEKTVEINKAGIRLAKEAAGTEAFVFGTIGGIKGVKQLDVSSEDIQ
NAFKEQAEALLSENPDGLMLETFYDLKETIDAVQLIRKLTDLPIITQVALGEVGVMHGGT
PVSEVFQKLKEAGADIVGLNCRMGPYHILRSLETVPLMKDTYFSAYPNASLPDLDDGRFV
YQSNPDYFYERAQDLKQQGVRLIGGCCGTTPDHIAEIARAVKGTTPVTEKVTVEETLADQ
LVSSQVPSDTVRLNEKKTKPSVIVELDPPKKLATEKFIQGAEELYKAGADAVTMADNSLA
TPRIDNLAMGAMVKNKTNARPLLHVACRDRNLIGLQSHLLGLHALGIQDVLAVTGDPTKV
GDFPGATSVYDVNSFDLISLMKEMNEGRSFSGKSLGEKTSFTVAAAFNPNVRNLERAVKR
LEKKIEAGADYFMSQPVYGKEQFKEIYEATKHLTVPIYIGIMPLVSSRNAEFLHNEVPGI
KLTNEIRQKMGACGEDKQKAQREGTAIAKSLIDEALKYFHGVYLITPFLRYDITAELTDY
IRKSALQR
>A0A1W1EDJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MFDKFCDILCNDKKFITIEVNPPHGASIDSIIENIKKYKLDEKVTGFTCTDNPLAKLKMS
GLLSAIKLQQEFKKPVIATMSMRDKNKLSLQSDILGANDFDLRCILALTGDPAKLSDQPD
VKGVLERDSTLLLSIIYHLNRGMDYSNKELNPAPKPIYPFAVSNAHAKDMKSLQKRMLKK
LNYGARAIITQPVYDLENARELLELFEEAKELSIRDTGKEAHLIIGQFPIVRAKTANFID
DKVPGITVPKDIIDDMNLAAMDGEEKEQEVGFALSKRIFDEIMKEHSKVHIMTHNRFDLC
SDLIG
>A0A1W1CAV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MFDEFCDFLCNKTKKFITVEVNPPHGASIEHILEDIKKYDLHNKVSGFSCTDNPLAKLKM
SGVLSAIRVQQAFNKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKFSDQP
EVKGVLERDSTLLLSIIYHLNNGVDYSNKPLNPAPRPIYPFAVSNSYAKDMKQLQKRMVK
KLNYGARAIITQPVYDTDNAQELLEIFEEAKNISVRETAKEAQLVLGQFPIVRAKTANFI
DDKVPGISVPKEIIDEMNLAAMDGEAKEQDVGFSLSKHIFDEIMQMHGKVHLMTHNRFDL
CSELIG
>A0A7K2P0H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5926|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTHFVD
KCRAGADYAITQMFFQPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A3B0UG11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MNEPKVTEHIAGSDKALFSFELLPPLKGQDFSAIQKTIDPLIEFNPAFVNITYHQQEVVY
DTLENGLMKKRIVRKRPGTVGISAAIKYRYGIPVVPHIICGGFTREETENALIDLNFLGI
KNLLVVRGDPPMGMKTFVPEPEGNAHSLDLVKQIARLNKGEYLEKDMKNYRSTDFCIGVA
GYPEKHSESPNLESDLHFLKKKVEAGAEYIVTQMFFDNQKYFDFVKNCRAKGIEVPIIPG
LKPVTTKSQMISLPQTFHVDLPEALVKEILKCKDNKDVRRVGVEWAIEQSKGLLKFGVPG
LHFYTMGKADNIREIAKDIL
>A0A416Y720|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. AF14-40|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A428DSZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFSYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A328LWD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. SRB_336|TrEMBL
MSPPVSHQSPPGSSAPIALSYELFPPRNETASASLWDTIRELEGTNPDYVSVTYGASGSN
RDTAVELLNRLMTESTLRPLAHLTCVGNSAAELAGIIAELLDHGVRGILALRGDLPTNPA
DPPGAGSLRYAQDLIELIRHVEQQRSALLCAGRVAIGVAAYPAKHPESPSIEYDLEVLLA
KQRSGADFAITQVFFHADQYRELVTRARRAGVTIPLIPGVMPLTSLRRVRRLGELTGVEP
APALLDALGRTAGPAEARRIGVAATVDLARAALDAGAPGIHLYTFNEHAAALDVLDRLAL
PRPARPKPLRRTALPELVQA
>A0A1S1R102|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. EUN1h|TrEMBL
MRDFLAAGEISYSFEFFPPKTPDGERALWRALREIEALHPSFVSVTYGAGGSTRDGTIRV
TEQIATDTTLTPIGHLTAVNHSVAELRQVIGNYAGAGVCNVMALRGDPPGNPQGDWVAHP
EGLRYSSELVELVKSLGDFCVGVAAFPDKHPRSPDPDSDADFLVGKFRAGADYAITQFFF
SADNYFRLVERVRARGCDAPIIPGIMPVTNVAQIERMAQLSGAELPADLVGRLHAVADDP
AAVRAIGIEVAVDLSERLLAGGAPGLHFITLNRSSATREVCQVVRAHHGRSGADHSGGVS
>A0A2S9I7M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea coffeiphila|TrEMBL
MSFFHANQREALNQSLAEINGQINVSFEFFPPRTAEMENTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATREELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMTSMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGVNANV
G
>A0A0S9NE37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodoferax sp. Leaf274|TrEMBL
MNTGTQPATPVSYEFFPPKTPEGAVKLRGVRQALYARKPQFCSVTYGAGGSTQQGTFGTV
GEILAEGVDAASHFSCIGATKETVRTQLAELRAMGVKRLVALRGDLPSGYGAGGEFHYAS
DLVAFIRAETGDAFHIEVAAYPEVHPQARSPEADMQAYAAKVRAGADSAITQYFYNADAY
FRFVEDSQRLGLAVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIKS
FGLDVVTTLCEQLLRGGAPGLHFYTMNQSVATLELCRRLGR
>A0A3B0YYY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MQTQKQYSPTFSFEFFPPKTEKGAENLKHTRDELGKLGPEYFSVTFGAGGSTQQGTIETV
LDIKQNGFNATPHLSCIGSTADNIRELLELYQNNGINRIVALRGDIPAGSEKAGKFQYAN
ELVEFIRQVSGDYFHIEVAAYPESHPQSKSPVTDLQHFKLKVEAGANSAITQYFYNIDAY
LYFVDDCEKLGLDLPITPGIMPITNYVQLARFSGMCGAEIPAWIRKRLQGFGDDKESIIA
FGADVVTDLCQKLLDAGAPGLHFYTMNQIKASRTLWNNLNLS
>A0A3R9IW23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDTVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1X1KPE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLNKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQAIRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A6RBU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces capsulatus (strain NAm1 / WU24)|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNILALRGDPPREKEK
WEAIEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDDQDDPDLLMQHLKEKVDAGGTF
IITQMFYDVDNFLAWVNKCRDNGITVPIIPGIMPIHTIPPDWLEALEPVKNDDVAVRNLG
KSLVANMCRKMLAAGIHHLHFYTMNLQQATKMVLGELELIPSHKTPLQKPLPWRQSLGLG
RREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYGIGLKGTNEQNIK
LWGEPKSLKELSEIFVRFLNGNLDRLPWSEGAVTEETDVIKLDLLDLNRRGFLTINSQPA
IDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNPDLTYYCVNKIGELR
TNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWAKCHGASSPSRRIIQ
QVMDNWYLVNIVNNDFHKTHDIFNIFKDLKVENLNVQVEPIAQAAELVDNAQENSQDPQK
QVNGSSTEVTESKQEISSN
>C6AS91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii (strain WSM1325)|TrEMBL
MALKNDARGRNIRVSFEFFPPKSEEMEGQLWHTVSQLQDWDPDFVSVTYGAGGTTRAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGVPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRPAAKQKVLAL
PPDLCASEGHAAL
>A0A0F2DZJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKSILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A7R9YQR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlamydomonas euryale|TrEMBL
MKVADKINARVAEGKPFFSFEFFPPRTEEGVENLLERQERMVAHAPVFCDITWGAGGTTA
GVTLDIASKMQNQICVDTMMHLTCTNITVDTLESALNEAKKQGIQNILALRGDPPKGQEK
FETVEGGFSCALDLVKFIREKFGDYFGIAVAGYPEAHPDTIVDDPEQMEKNYWDNIKYLK
QKIEAGGQLIVTQLFYDVDIFFKFIKDCRSVGIDVPIIPGIMPIMTYGGFKRMTGFCKTK
VPQELHDKVESLKDDEAGLKAFGIEHGAEMCKRILEGGVPGLHMYSLNLDAAVFGILEKL
GMLNPGKPPKSLPWKCIPAGTRRASEAVRPICWANRHRSYIKRTAAADSFPTSSWGTSSS
TMLGSLPSPESLRHHTASAGRRTKAAEAWGGSLETVSAVATLFTKFYAGELASLPWSESA
FSGPAMLASKQSSLISSGMLPINGQLALNGIESTDEQAGWGGPGGRVYQKSYVEAFVSPD
AYKAMLPKLQARSGITFAAANKAGTCKDCSASADSVSAVTWGVFPGREVVQPYVFDVTSF
RSWAEEAFALWSAELAHAYEPGSATAKALEEIAGSYYLVAVLDEDFVAGDAFTALA
>A0A243BCL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar poloniensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1B4BNQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia diffusa|TrEMBL
MKSIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDNLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAAAATRTICERLTM
>A0A2H5YE12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR23|TrEMBL
MTRFQDALASGRFVVTAELNPPKGTDLSEVLGKAQALRGVVDAFNLTDCTGARMAMAPIA
VAHLLLDQGIEPILQVTGRDRNRIAIQAELLAASALGIENIAIMSGDPPGTGDHPEAKAV
FDLEAIGILKAASALMQGHDLAGNPLKGTPRFHLGAVVNPGAKDLDKELRRLEEKIAAGA
RFFQTQAVYDPDKFSAFMKQVEHYRLPFLAGIIVLKSAGMARNLNQNLPGVLVPEHLIAE
LENAPDRTAKGIEISARIIREVRSLCQGVHIMAIGWERYIPAILAQAGVAVPAS
>A0A0A0BCB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas cellasea DSM 20118|TrEMBL
MPAPAPTRSRDVRAAVDRPTVSFELFPPRNPDAAPKLWATIQALGEARPDFVSVTYGASG
KTRDTTRGLVRRLLRETSLNPIAHLTCVGTSRAEVTAVVEEFLDEGVRSFLALRGDPPAD
QPDWRPHPEGLETASELVALLREIEERRCRGSLAQKVRATVRPLSIAVAAFPRGNAGTGS
TRAQDVAALLAKQEAGADFAITQVFFDAGSYLELVAEAREAGVTIPIIPGIIPTTDPARL
LRVEALTGVTVPRPLLDRLGSVDDDAERHRVGIRASVDLVNAVLDGGAPGVHVYTFNTHH
AALDLLEGAHLGGGAPTAPDRAPGPQAGSPSPVPAPTN
>W6YAY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bipolaris zeicola 26-R-13|TrEMBL
MHISQKLAQAKREGKPTFSFEFFPPKTAQGVQNLYDRMDRMHSFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALREAYQAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDDVDELIDHLKEKVDAGGSF
IVTQMFYDTDLFLEWVRKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTKCHIPDDWTKAL
EPVKNDDVEVREVGKTLVADMCRRLIDAGITHLHFYTMNLAQATRMVLEELELLPDVESP
LEKPLPWRPSLALNRREENVRPIFWRNRQRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPLTIRDFSNLFVRYMEGKLESLPWSEQPITAEASSIRDDLID
LNRRGFLTINSQPAVNGVKSSDPVFGWGPRNGYVYQKSYLEVFVSPEHIAEIITRLERDP
EFTYYAVNKNGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGISPSRYVIQDVIDTWYLLNIVHNDFHATRGIFPIFNGLEVKDMDKPLHTPSADL
PNANGSENVNEANGVNGTNGTHKEESPSLIDVAKAAAIEVTNGMKSLAVSN
>A0A3N1D2H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinocorallia herbida|TrEMBL
MTRGFEVVCEIEPPTRPDLRRVRHQIGVLDAVADAFLIPDNHIGRATVSSVAVAHEVQAM
GATGIACLNARDRNLLGFQRDLLTAAAYGVQRFLFVYGDKPASGNRTGELTVRSMLDQAR
AATADPVFAGHPRFQIGVASGMRPLPAWKQQADFVFAQVSYSLDDLLRWRETVTIDAPVY
AGVMVLASAAMARNLAATIPDITIPDALVQAVEHDPDAGIAAACEHVMAIRDSGAFDGVH
LVPVSRYRQTAARLEPLLREPPRNPR
>Q0ALW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maricaulis maris (strain MCS10)|TrEMBL
MGEHGQAARKPDGLSVSFEFFPPKTDAMESTLWESISRLEPLRPDFVSVTYGAGGSTRDR
THRTVHRIVEETSIPPAAHLTCVNASKAEVDGVIRDYWKSGVRHIVALRGDPPDAIGGSY
VPPAGGYANAAELARGISDIGDFEISVGCYPETHPESPNAGFDIDLLKAKIDAGATRAIT
QFFFDADVYFRFRDRARAAGITIPIVPGIMLQPNFKGLKRIAGLCGASLPKWLHEAYEGL
DEDAGTRQLVTAHVAAKLCGKLRNGGVDGFHFYTLNRAELALSTCQLLGVKAGDRELQAV
AS
>A0A1H9Q345|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. NFR03|TrEMBL
MSTRTLYPAERGDLRLSFEYFPPKSDEMDAQLTRTAAALNAYAPEFVSVTYGAGGSTKAR
SLTTVRRLIDDCAIPGTAAHLTCVGATRADVDAVVEEFAAAGVRHFVALRGDPQGGIGAQ
YQPFPDGYENAAALVASLARSGRFQISVSAYPEKHPESLDVDADIDMLKRKVDNGATRAL
TQFFFDNNDFERYLERVRKAGISIPVVPGILPINQFAQVAKFSGLCGARIPEALSARLAH
LDDAPEERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLIMAVCDLVGFKRTQEPAVE
GAAA
>A0A2A6E3Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Reconcilbacillus cellulovorans|TrEMBL
MTEKLDLRRALAERVLVGDGALGTLLYQMGFPVGISYEELNLTRPDVIADVHRRYREAGA
SVIETNTFSANRLKLARFGLERRVADINRAGVRLARKAAGPDGYVAGSVGPIRTQGQRHA
SLRDLRSAYREQIEALLEEGVDAIMLETFEDVDELELAVETVRRLSDVPVVAQLALEDVD
ATPSGRPVADAIAALRDAGADVVGFNCRIGPSRMVRLLEAIPAPLRASVPFSVYPNAGFA
EYVEGKFRYGTPPEYFSEIAVRFVERGARLIGGCCGTTPEHVAAIAQALQGVRPADDGAV
RASGWRMEIRTAAGDGPEGGRGEKSDADTGSAAATAVPTLLDLVRTRHTVVVELDPPRDL
DMSKFMEAAKTLRDAGVDALTMADNSLAMTRMSNLAAGFLVKERLGVRPLIHIACRDRNL
IGTQSHLMGLHALGIDHVLAITGDPARFGDLPGASSVYDLTSVELIRMIKQLNEGISFSG
KPLKHRARFVVGCAFNPNVKHLDKALERLEKKIEAGADFVMTQPVYDPALIETVGEAARR
LPVPVFLGIMPVVSEANAVYLHNEVPGIRLPDAVLRRMAGLKGERGREEGIRIAKELLDV
AIGLFHGIYLMTPMLFSSMTAELTRYVWRMTGRAAAGLPTCSSG
>A0A7G9P055|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetales bacterium zrk34|TrEMBL
MTIRFPQIYQQKAPTFSFEFFPPKTDAAQQRLRDNVTELKALGPTYVTCTYGAGGSTRQQ
TGQIVAELARELQVPAAAHLTCVGNSREQLIEVLEGFAAQGIANIVALRGDAPAADASSG
GVATFEPHPEGLRYANELVTLIRERFGDTFGIAVAGYPEGHIETPSRLTDLDNLKRKVDA
GADMVMTQLFFDNRDFYDFVERCELAGITVPIVAGIMPIVTRAGIMKMAGLCGARLPSKL
LKKLQAAGDDDEKVARVGIDWATRQCHDLLEHHVRGIHFYTLNRSNATIEIYRRLGATDS
QTLADIAGDG
>A0A7H0VCE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceimicrobium hydrocarbonivorans|TrEMBL
MKVTEHIAQAEGSLFSFEILPPLKGQKIEDIYKVIDPLMEFKPPFINVTYHREEVIYKRL
SNGLLEQKTVRKRPGTVGICAALQYRYKVDTVPHMLCGGFSKEDTENALIDLDFLGVKNI
MALRGDSMKNERFFAPEADGHTYAKDLVGQIKAMNQGRYLDDELQNSAPTDFAIGVAGYP
EKHFEAPSLNKDIEYLKEKVDAGADYIVTQLFFDNRKYFDFVDRCRKAGIEVPIIPGIKP
LSTKQHLSFLPHFFKVDLPDELVKAVVDCKDNAAARQVGVEWGIQQAKELKAAGVPAIHF
YSMGRPDNIASIAREVF
>F9DUC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina newyorkensis 2681|TrEMBL
MMSLLEKLQTNVLTADGAMGTILYSYGIDYCYEELNIEKPEIIEKIHHDYIEAGADIIQT
NTYSANAVKLARYGLENRVTEFNKAAIQIAKRAAAPGGQFVLGTIGGLRGIRKSDASLDE
VRQVVLEQANALLTGDPDGLLLETYYDFEELSSVVSTLRQITDVPLIAQVSMHDPGVLQN
GLSLNDALHQLESLGASIVGVNCRLGPYHTIQAFENVKLPENAFLSAYPNASLLDVEDGR
IVYESEAEYFGRAAVLLRDQGVRLIGGCCGTTPKHIKAAKTRLAGLSPITKKVVEPTKPI
VIQEAGPVKHQPLHEKAKTERTVIVELDTPRHLETEDYIKGANLLYDAGVDAVTMADNSL
ASPRISNMAMGSIIKMQHNIRPLVHLTCRDHNLIGLQSHLMGLDALGIHDILAVTGDPTK
VGDFPGATSVYDVSSMELLQLIKQLNEGISFSGKPLRKKTNFSVSAAFNPNVRVLDRAVQ
RLEKKIEAGADYFITQPVYTKEKIIDVYEATKHLDTPIFIGIMPLTNIRNAEFLHHEVPG
IKLSDEVLERMRACGDDRAKATETGIQIAKELIDTAAQYFNGLYLITPFLRYDMTLELHD
YIKQIDKQKESELSHAETSY
>A0A7C2AXE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MDSQKFYPLAFSFECFPARTEQGSSRLLDSCRALATVNPCFFSVSYGAGGATREHSLSAV
SHIRKTTAIDVAPHIAAIGASYDEINTLLQHYQQQEVRHIVVLRGDTPSGLLDCGDFNYA
SDLIQFIRDKYGDYFFIEVAAYPEIHPQATNPQADLINLKLKFDLGADAALTQYFYNPDA
FFRFIDECEKLGIDQPVVPGIMPITNYHQLARFSDICGAEIPRWIRQRLVGYGDDIASIR
SFGEEVVTRLCEQLLKGGAAGLHFYTMNQSAPTLAIWNNLGLSSDKSDRARRLM
>A0A023CTA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parageobacillus genomosp. 1|TrEMBL
MGLLQDLKERILIADGAMGTLLYSHGVDRCFEELNLSKPEDIIHIHEAYIAAGAEVIQTN
TYGANYVKLSRYGLADEVPAINRAAVRLAKQAAKNKAYVLGTIGGLRSINKSAVSIEEVK
RTFREQLFVLLNEDVDGLLLETYYDLEELETVLAIARKETDKPIIAHVSLHEVGVLQDGT
PLAEALARLEQLGADVVGLNCRLGPYHMIRSLEEVPLPNRAFLSAYPNASLPDYRDGRLV
YETNTDYFKETALAFREQGVRLIGGCCGTTPKHIEAMANALVDRTPIKEKVVKQRHVPIS
IQMNEPNTTPPLQDIVRERRSVIVELDPPKKLGLTKFLEGAKALKEANIDALTLADNSLA
TPRISNMALGSIVKEQLGIRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVER
LEKKIQCGAHYFITQPLYSERQIEEVYEATKHLETPIYIGIMPLVSARNADFLHHEVPGI
TLSEEIRARMAACGNDPVQSAREGIAIAKSLIDTAFDLFNGIYLITPFLRYEMTVELVRY
VHEKEKAAQERKVLHG
>A0A5F9C7S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryctolagus cuniculus|TrEMBL
MVNEARGNGGLHPRSEGSSSGSESSKNSSRCSTPGLDPERHEKLREKMRRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETMLHMTCCRQRREDLTAHLHKAKQLGLKNILALRGDPVGDQWEEEEGGFNYAVDLVKH
IRSEFGDYFDICVAGYPKGHPDAESLEADLKHLKEKVSAGADFIITQLFFAADTFFSFVN
ACTEMGITCPILPGIFPIQGYHSLRQLVKLSRLEVPQEIKDVIEPIKDNDAAIRNYGIEL
AVSLCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKCPREELLQMW
GEELTSEESVFEVFVRYLSGEANQQGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPVVGWGPGGGYVFQKAYLEFFTSRETVEALLQVLKNYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKASSEGGRDGGPVTQPAV
LRWGRPYPTLLPPRPSCPHSRTLVSTPPHDGS
>A0A089M405|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus graminis|TrEMBL
MKPDLRSAWKNNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYIGAGAVL
LESNTYSANYDKLSKFGLEAKVGDINRAGVRIARRAAGDSGYVVGAVGSIRAGKRANLSS
TELKRFYAEQFSALLEEQPDGILLETFYDVEELHLALRSVRKLSDLPVICQLAVDETART
LDGLTLPEAFHILEQDGADIIGFNCRTGPNGIKRALKSLQGNLRLPASIYPNAGIADYVD
GQYRYGASPEYFGQMAPVFADMGARIIGGCCGTTPQHIAEISAALRDYTPQPLPEPTGQR
NSERLMVQEHLAEDEERDGREPTLVDLVKERHTVIVELDPPRDLDIAKFMRGAEALRKAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHVACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIKQLNDGIAFSGKPLKQNANFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIARIAKATEHLEIPIFIGIMPLASGR
NAEYLHNEVPGIQLSAEVRTRMQGLEGEAGRAEGVRIAKELLDAATAHFNGIYLMTPFMF
YDMSVQLLEYVWAKQGRKLSPLFR
>A0A6W0ET61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Heidelberg|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAKADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1Q3LQL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. 69-7|TrEMBL
MYPPRTPEQLPALYETIRVLAAAGPRFISVTFGAGGSTTDRSLTVLTHILRETTVPPVAH
VTCVGSSYAEATTVIRDFLDAGITRFLALRGDPPAGVGEDDIVVGDLESAAQLVQLIGRV
QAERSPYREREIPGLPGAVQVTDGDRVEIAVAAFPNGHPRSRHRYEDIDALLAKQAAGAT
SALTQLFFHADEYLDFVERARAAGVVIPIVPGIMPITSPGRLRRVLELTGDARPDSLAAA
LESAPDAAAQRAVGLAHAADLARSVVAGGADGIHLYAFNNHDTVLGVLRAAELIPEASP
>A0A3M2SBP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium kuroshium|TrEMBL
MHIKEMLTDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRDQDK
WTAADGGFQYARDLVKHIRSTYGNHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKKVRERGVNVPILPGIMPIATYASFLRRANHMKAKVPQAWLDAL
EPVKNDDVAVRDIGKSLVAEMCRKLLANGIHHLHFYTMNLAQATRMVLEELNWAPSAERP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTVQDIAQLFVRYLRNEIDSLPWSESPLTSEADEIRDDLVE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPSNGYVYQKSYLELLVHPDVFNDMIGRIEGHP
DLTFYAVTKDGELRSNAPSDCPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDASSPSRALIDEVMNEWYLVNIVNNDFHQNGTIFELLKGLEVKDLTTPATPKSEPE
ANGTEPLANGTAAA
>A0A066VJJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tilletiaria anomala (strain ATCC 24038 / CBS 436.72 / UBC 951)|TrEMBL
MTSTPHANWRITDKIAKAERDGSIWWSFEYFPPRTSQGLTNLYDRIERMGQLGPEFVDIT
FRMGSADLTYQLVDTVHSYMGLETCMHLTCTNMPRAEVDHALDEARRHGCRNILALRGDP
PLGKDEWEGHADGFTYAKELVEHIRAKHGDYFAIAVAGFPEGHIEAKDGEAIEMQRLKDK
VDAGADFIFTQMFYDYDIFDDWVRKVRRAGITCPIVPGVMPIQNYGGFQRAVARFRTKVP
QEFYAALEPVKDDDQKVREVGTRLVGDMCRRIIESDLGIHGLHIYTMNLERGPRMLLDYL
GLTPDVGKVRPIPWTPSLTPKRRDEGIRPIFWANRAKSYISRTETWDEFPNGRWGDARSP
AYGDFDAYGVQLHWTPEEGQQMWGSPQNLDDIRRLFCDFCAGKVKALPWTETGIAKETSV
INDKLVRMNQLGFLTINSQPAVDSAKSTDPVHGWGPKNGYVYQKAYLEFFVSPEQLDALI
TRIESDAQFTYHAVNARGDMRTNTNSESPNAVTWGVFPHCEIIQPTIVESISFLAWKDEA
YQLGREWAKIYPVDSVARKVINDTFDRFFLVNIVHNDFKRKDAIFEPFFDVASASNGYRG
VNGSTQAINDTSASLVHKAQGLKDSVLPKTGSGSAAFN
>A0A242AYI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus sp. 7F3_DIV0205|TrEMBL
MRTDTLFKEKTVFSYEIFPPRRTAPIDTIYHTLDRLKGQQPDFISVTLGAGGSGANLSTA
DIAQKIQDEQFLPSVAHLPAVNFSKDEIIVILEELKQKKVENILALRGDILPDKEPKRDF
SYANDLVAFIQEQGDFNIIGACYPETHGDAVNTVEDIRNLKRKVDAGTNQLITQLFFDNH
YFYTFKEKCDIANINVPIQAGIMPVVNKKQIERMVKMSNVTLPTKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVAQGVDGIHLYTMNNPYVAQKIREATRSLFNV
>A0A242ZP38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar kim|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8J3GBQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cerasicoccus arenae|TrEMBL
MRMSRDILSKFADGHKVFSVEFFPPKTEEGARQILRTAHALKAHEPDFVSITYGAGGSSR
ERTIEYGELLRDLFGFEVMPHLTCVGHSRDELTSILERFQESDFHNIMTLRGDPPKGQTS
FEPHPDGLRYASDLVAFIKERFPNFCLGVGGYPEKHPEAMDMDTDLANLQTKVNAGADFI
TTQLFFNNADYFTFVERCRGLGIEVPILPGVMPAMSFDQVNRFCGFCGARVPRELAAKLE
CVKDDPEASEAVGVEWALQQIRGLLDRGAPGVHLYIMNRSGAAIALMEKLRAAKV
>A0A135W7D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. HYO08|TrEMBL
MGLLDRLQKNVLTADGAMGTLLYSYGIDFCYEELNVSKPEVIEKIHQEYIAAGADIIQSN
TYSANAIKLARYGLEDRVNEFNEAAMQIAKRAAAPGGQFVLGTIGGIRGVRKSDASLDEI
IRTVESQAAALLSGDPDGLLLETYYDFEELAATVTRLRKLTDAPIIAQVSMHDPGVLQNG
YSLNRALHELEALGADIVGVNCRLGPYHTIQALEGVSLPEKAFLSAAPNASLLDVEDGRI
VYVSEADYFGRAAVLLRDEGVRLIGGCCGTTPKHIEAVKKRIADLPPIAQKIVKKPEPIV
IQEAQPAKKEPLHIQAQTERTVIVELDTPRTLETEKFIDGANALHAAGVDAITMADNSLA
SPRISNMAMGAILKQLHHIRPLVHITCRDRNLIGLQSHLMGLDALGIRDILAVTGDPTKV
GDFPGATSVYDVSSLELTQLIKQLNEGISFSGKPLARKADFSVAAAFNPNVRVLERAVQR
LEKKIESGADYFISQPVYTKEKIKEIYEATKHLSTPIFLGVMPLTNIRNAEFLHYEVPGI
KLSEEVLERMRACGDDRARSTEEGIKIAKELIDTAAEYFNGIYIITPFLRYDMSLELIRH
IQEIDKKKERGFVHAESTH
>A0A413VZI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster aldenensis|TrEMBL
MKTSEFFKQKTVLSLEVFPPKRTAPVDTVYKTLDGLKGITPDFISVTYGAGGIGNSRATL
EIASSIKRRYGIESVAHMPCLHLTKEEAARILEQLKEHQIENILALRGDRIPDMEPAGGF
KYAADLVAFIRDHGDFNIIGACYPEGHQESGDLVQDIRNLKQKVDAGVSQLITQLFFDNQ
YFYRFRERLDLAGIRVPVEAGIMPVVNKKQIERMVSLCGVKLPQKFISMMERYGDNPAAM
RDAGIAYAVDQIVDLAAHGVDGIHLYTMNNPYIANKIHESVFRLMAS
>A0A841PH86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomicrobium halophilum|TrEMBL
MREQQLPVAQFGQMSEPRFELIPTHRIVERAEAALPPHATLTITCSPKKGVDATIETAVA
LAPRFARVVPHIAARMVRSEEHLEAVLDKLLAHDLEEIFVIGGDERQPLGPYRHGLDLLE
FLATREHGIRRIGIPAYPEGHPDIDNDILAKDLLAKAPYAHYAVTQMCFDPDRVLAWLRR
QREAGLGLPFYLGIPGPVKPDKLLRIATRIGVTDSIRFLRKNFKLTGKMLRGYDASDLLN
AYAPHLNESDHGIAGFHMYSFNELDTLKKIFARIAI
>A0A3S9HYH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces aquilus|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMADWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDTDVEHFVD
KCRAGADYAITQMFFKPESYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPQLSNASI
PSVLKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A5D6XIV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pythium brassicum|TrEMBL
MKIADKIHASIEKGEVFYSFEFFPPKTPAGVDNLYTRMDRMAALEPLFCDMTWGAGGSSA
QLTLDLSANAQKLSGLDMLMHMTCTNMAEADVRVALDKAKDAGIQNILALRGDPARGAAS
FTECDRGFSHAVDLVRYIKAHYGDYFSIGATDIRYLKEKVDAGADFVITQLFYDVDVYTT
FVANCRAAGITVPIVPGIMPIQNYGGFVRMTSFCNTLVPPAITDALAPIKDNDEAVKDYG
VALGIAMCKQLVAAGAPGLHFYTLNLERSVRRILDGLAIATENASRRELPWRPSPLAKRA
AESVRPIYWSNRPKSYVQRTAMWDEYPNGRWGNNESPAFGELTESHYVSTVITPESRRAM
WGAAPASAADVYETFVRYVRGEISSLPWCDSPLHLETKTIQDKLAAINAAGFLTVNSQPR
VNAARSDDPLFGWGGPGGRVYQKAYVECFVSPENMKKIIDAAAATRSIQYYAVDSRGHSY
SNAGKSAVAVTWGVFPNKEILQPTIVDSSSFMAWKDEAFALWLSLWGSLYERESAAAAVI
RAIHASYFLVSIVDNDFVGGDIWRIFDAAAPAPAAPAAPAAAPAAP
>K0VKP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Pop5|TrEMBL
MALKNDGRGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWDPDFVSVTYGAGGTTKAPTL
SAVTRFLSQTPLATASHLTCVGATKEETHHMIETFRKVGVKHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGVSIPIVPGIMPIQNLTQLKRFAGACGAVIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGLDEFHLYTMNRAPLVSAVLDNLGFIRRAPKSAGAAA
>A0A2K4TBL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. persicae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1F9NZP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium RIFOXYA12_FULL_46_15|TrEMBL
EVVPPKGNDPAPLLEKLQSLAGLDFHAFSVASNPVAKPRMSAMVFAHLIRNATQRRAILH
CTTRDQNRLGLQSELWGAKALGIDTIIAVTGDPSSANTGETTSTVADLTVYDLISLAGDS
GLFTGAVLDFRPEVNGLAHEAERLEKKAEAGCRFIVTQPVYDEDTAKNIHDAVKHLKVPV
VMGILPLLSYRHAVFLNDKVAGIAVPAHLRKEMETAKIPLSVGISQSRQMLSLAKTFFSG
ACIMPPFDRFDILKEILA
>A0A1T4QS60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carboxydocella sporoproducens DSM 16521|TrEMBL
MKAGSKLEQLLRRGEFVVSGEIGPPKSCDANVIKKHGEHLRNAADAFNLTDNQTAIVRMS
SIAAGKILVDMGIEPIIQMTCRDRNRIGLQSDALGAAALGIKNILCLSGDHQRFGNHPMA
KNVWDLDSIQLLQTLDGMRKGYFQCGEQMKSEPPKFFLGCAANPFADPFEFRVTRLEKKI
NAGADFVQTQCILDMERFERWMELVRERGLHERAYILAGVMPIKSAKAARYMQKNVAGMM
VSEEICQRLEKAEDVKEEAVNLVVEQIKYLRNMKGIAGVHIMAVAWEEIIPTIVERAGLL
PRPTI
>A0A382Q666|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MSAFSNELATPNFLVTSELTPPKGTDLTDLLQKAQSLKGIVTAFNLTESHAARMSMDPVA
AAHVLLDHGIEPIVQMTSRDKNRIAIQASILGAAALGISNILFMGGDPPKNGDHPDAKPV
FDLFSSQLLEAAQALRSGTDLTGHHLRGTPVLTVGAVFNPGASDVSDEIENLRRKEDGGA
EFFQTQAVFDPTAFEQFIEKARPTRPVLAGVIPIKS
>A0A381RE76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MEILNLKSDSFESNMSTELTNHVEENAGQTTTWSMEILPHNISNLSLIPDFVNEVYITMI
PGASCRETIQTAHQIQAVGKQAVPHITGRSFKGVEELSACLSELQETGIDRALLIGGGQS
EPAGDITCVMDMLKTGLFAKYGINAFDFAGHPEGNPDDPNSEAHLLEKLLWTEERGIPAR
IVTQWCFDSDGTNDWISGLREKGIRNPIHIGIPGPSTMKTLLSFAKVCGVQASARVLRKQ
GLNISKLMFVNKPDKIISELRGYDKLHLYPFGGIAKSADWLNEWQRINC
>A0A382DC26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MNMISQLHKTLDSGTFTVTAELTLPDSSEKDELVNTALKLSPYCDALNVTDATSAIPHFS
SLAAAAILLDNDIEPVMQISARDRNRIAIQGDVLGAHSLGIRNIFCITGDAVIAGDHPDA
KPVFDLDSISMLAAINKMAKSGSFMSGRKITPKPTLFLGAAANPFAPPHDYRPHRTVKKW
KAGASFFQTQFCFDIKAMERFSEKLVELSDGKPPPVLVGLGPLKSSRMAKWLRDNIAGVS
VPDQIIERMDKYPRKEQAQVGLEISKETINDLKSIQGVAGIHIMAFKWEEAVKEIVEDSG
LAKHKRLP
>A0A381Y6V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MNTSFEYFPPKTDKGKENLVDLTKRLSYLSPEYFSVTYGAAGSTRKGTLDTCISIKNLGQ
KACPHLSGIGSSKGVIKEILNEYKDHGLTKIIALRGDLPSGIGGFGDFPYALDLIKFIKR
EQKSFSIEVAAYPEVHPDAESENTDFENFLNKVDAGADGAITQFFFEEDSYFKFMEKCEK
EKVTIPIIPGIMPIHDFEALVRMAKNCSANVPMWLKEGMQKYSNNEDRFMYGVEVITKLC
QKLLRFGAPGIHFFTVNKEEPTSSIIKNLETK
>A0A382V7U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MNISFEFFPARTEHGKKALNEVQKKLSAIKPEFFSVTFGALGSSQDATFETITDLLKNTN
VPIAPHLTCVGIKKIQATALLDKYIELGVNRVMVLKGDTPQVRFPYKNSRDKGDFHFANE
MVEFIKEQYKGYFHIQVGAFPEKHPQSKSFTNDIKFFV
>A0A381SVG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
VATRARADRAVQKRLLEGMTYELIPLKNLADQSMFLPAGATVSVTCSPAKTIDDTLDLCA
HYGNQGFTVIPHLAARMAEDEDHVARIVRRVNEQGIRKVFCIGGDAEPRGPFTDAARFLR
SFLDHRPEIEVVGVGSYPDGHSTIPEQALVDSLVEKQEMIREAGLKGYMATQMCFSANTI
GDWLKNRRLAGVDLPCHLGVPGAIDRTRLLTISIRLGIGHSARYLKKNSTSVIRLLSPGG
YNPNKLIIPLSTRAEELGIVGIHCFTFNAVDTTENWRQKSLQKLG
>A0A6N8Y7C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MNFSEYKNKKKDTPLISFEVFPPKDDPEFEKLKDTLARLAELSPAIITVTHGAMGKGRKR
TAEVASYIKNVIGMESACHLTCIGYSEKEIDLMLEQIEQEKIRNIVALRGDIPKENGEKL
LSEGAFQHANQLVEYIRKYEKEKPQRFSVAVAGYPEKHIESPSFEEDISNLKKKVDAGAD
IIITQLFFDNRYYFDYVDRVRAAGIDLPVIPGLMPVLSSKQVIRISSLCGTEIPEALRKK
LEDAGDDNRKAVEVGIAQCRDQVRELIAEKVPGIHFYVLNRTSHIERILESV
>A0A381RQG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MRISEKLKSRSPVFSFEFFPPKDEGGFQSLFETIEKLKPADPGFVSVTYGAGGNTRSKTV
DLVGKIKNEIGIESMAHLTCVGHQKDEIISVLKSLENCGIENILALRGDPPKGEEQFIKP
EGGFGYSNELVSFIKSNFSFCVGAACYPEGHIECVNLSQDMDNLKRKVDCGVDFLITQLF
FDNRYYFDFIKRAEKEGINIPIIPGIMPILNLKQSQRFTKMCGASLSDSLIAKFNGFKDD
LDKVREIGINHAIEQCRGLINSGAPGIHFYTLNRSKATLAILENLRG
>A0A381V388|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
VAYEILPPREKDGTLNSYAETISSLLSQTHIDAINIPEVHDEIERGDRPVTNQKRGEPRE
FGMLLQDIVGIEAIINRVVVHEPYEEQMRWIEETNTTYEIENMIIVGGESSKVDYPGPSV
NEMLQTIARGYNSNGGDIFCGGIAIPSRKDESKNLIRKSEHGSEFFTTQVLYNAENIIKM
INNYQSRCNELDT
>A0A382TJP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MREDLENAYMEIFPVPGIEERLGALQPNANVAVTCSPTKGVDATIELSEKLIAQGFQVIP
HIAAKCVSGEKHLETIVKRLDALSVESIFVPGGDRPEPIGEFNNAYDLLKALQKSGHNIK
DIGIAAHPEGHPDINEKILMEALEKKKDLADYIVTQMCFDANILGDWLVRINQQGVHLPV
WVGLPGAIERGRLLRTSLRIGVGDSLRFLRKKSQVAAELMKSSIYNPDKLVTSISEYKDI
ADTNLAGYHIFCFNQIEITEKWRT
>A0A838G8M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MRNKLQTAFVAEMLRSARYEVLPTATIEERILAHVPVDRTLTVTASPAKGIAETLALAER
LAAHGYRAVPHLAARMVSGRSELAEICARLTDAGIDTVFVPGGDQDPPSGDYTSALDLLE
DLTALGRPFAHVGIAGYPESHPTISDDLTVQSMWDKRSHATHVVSNLSFDPATIDVWVAR
LRARGIVLPLVLGIPGPVDRTKLLAMATKIGVGDSTRFLAKHKGTFARLAAPGGFTGERF
LEGCAPALSRPEALVSGLHVYTFNQVAETEAWRRRYLDRSALVR
>A0A6L7TZ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MREIRPVRRNSRGKTVNFSEYKNKKKDAPFISFEVFPPKDDPEFEKLKDTLARLAEFSPS
IITVTHGAMGKGRKRTLEVASYVKNVIGTESACHLTCIGSSEKEIDLMLEGIEREKISNI
VALRGDIPEKDGENLLSRGAFQHANQLVEHIRKYEKGKPQRFSIAVAGYPEKHIESPSFE
EDIANLKKKVNAGADIIITQLFFDNSYYFDFLGRVRAAGIDIPVIPGLMPVLSSRQVIRI
SSLCGTDIPAPLKKKLENAGDDNRKAVEIGIAQCRDQVRELIAEGVPGIHFYVLNRTSHI
EKILKSV
>A0A381Y2G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MNINQKELNIRILLKNCSIETSPNIYAKYGKFSGLVPISSAVYITYLPDETSSRVIDTAK
KLTDEGFDVVPHLPARTIKNNFELESFIGNLSEKAGCNKILIIGGGGNQNGNINSSLDVL
KTDLLSKYRFIEVGLAGHPEGNPDVTEEELDKAIIEKNEFVKNADFKAYLITQFFFEASS
LENWEKKLVSLGNELEIHAGIPGPATLKTLIAYATSCGIGNSIRFLSKQALNITKLATTR
TPDKLITDLANYKQKNPCSKLTKLHFYAFGGIKKTSSWLDEITNSK
>A0A382NVN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKVIEHIAKAQNPIFSFEIIPPKRGTSVQEITNIVKDLEPFNPPYIDVTSHSAEAYYEEG
EKGIVKRYVRKKRPGTISICGIIQNRFKIDTVPHLLCRGFTKEETEDAVIELNYLGIHNI
LAIRGDETNYKKPIESGRS
>A0A1Q7K0F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_40CM_4_65_8|TrEMBL
MQSFREAIEDRVLVCDGAMGTMLYAKGVFINKSFDALNVAQPDLVAEVHQEYVRAGADII
ETNTFGANRIKLGSFGLADKLHAINEQGAKIARHAADDRAYVAGAIGPLGIRIEPWGKTG
VDEAREYFREQAQALLDGGVDLFILETFRDLNEIGAAIDAVRSISDLPIVAQMTTEEDGN
TLDGTPPERFAPELEKRGATIVGVNCAVGPAPMLDTIERIAAVTPLKLSAQPNAGKPRDV
EGRNIYLCSPEYMASYARRFILHNVRVVGGCCGTTPDHIRQIKTAVRSLAPGLVRGASRA
EPPAESGGAKAGGVSRATVSAAIASPPIAREHKSRLAHAMAKGTFVVAVELLPPRGYRAD
DVIERARQLKIQGVDAVNIPDGLRAGARVSALSLAVLIEQQAGIETLLHYSCRDRNLLGI
QSDLLGAHAMGLRNLMLITGDPGRVGDYPDATAVFDVDSIGLTNVVSRLNRGCDVGGQAI
GAPTGFHIGVSVNPAASNLDQELRRFEYKVEAGAEFIVTRPIFDVAAFERFLTRIEFARL
PVVAGLFPFESARNAEFMANEVPGVRVPDAMLERMRRAEGAETAAREGIAIAREIAASLR
SAVQGVQIATASGDIDAALAVLDGLR
>A0A838FTK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MARGLQSLLPRREPPLSQVLSSGDPSYSFEFFPPKDDAGERALWAAIRELEPLQPTFVSV
TYGAGGSTRARTVRVTEGIAAHTTLRPVGHLTCIGHSRTELRSIIGQYADAGVANVLALR
GDPPGGPGAPWSRHPQGLDHAVELVEMTCSLGDFCVGVAAFPDKHPEAVDRDADARVLAA
KARAGARFAVTQLFFHADDYFELVDRAARFGCDIPVIPGIMPITNLSQVARFAALSGSVV
PATVVARLEPVQDDPAAVRAVGVEIATELCDRLLAGGAPGLHFYTLNRSKATREIYANLA
VGVT
>A0A382AB68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MIVQPATTLEKQLNGGIFTVTGELSLPDSPTEESLLDRARRLSPFCDALNVTDSTSATPH
FSSLAGSAILHRNGIEPIMQINCRDRNRIAIQNDVLGAHALGIRNILCITGDGVESGDHP
EAKPVFDLDSVSLLSTISLLKKEGQFLSGRKLESKPNLFLGAAVNPFSPPFDLRPLRLLK
KQKAGASFFQSQFCFDVPRFNTFMSELLDACNGTPPPVLVGVGPLRSAAMGLWMRENIAG
VSIPDSVISRMSKYAKDEQSKIGIEICSETVTMLKGIHGVAGIHVMAYKWEGAVREIITN
TGLQKENRN
>A0A3N1T1W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CEV 2-1|TrEMBL
MDSLSTASAPAVGPLLEDFSLEMTGKDVPRLEEARDRIPAGTRINITFLGNEDLGVRLAA
ARAVRQLGYTPVPHISARRLRSRAELEELLAAFRADGTADNVLVIGGDPATPHGPYDDSL
ALIRSGLLQSYGVRHVGIGGYPEGHPSIAGPVLWSAIEDKTTALAGQGLSGDVITQFGFD
ADPVLAWVESLRKRGIDAPVRVGVPGPAGIKRLMTYAARFGVGTSASIAKKYGFSLTNLM
GTAGPDRFIRALADGYDARRHGVLKLHFYTFGGIGATSRWVTEFLAVEGN
>Q9PEA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylella fastidiosa (strain 9a5c)|TrEMBL
MIPISFEFYPPKNDDQRAQLDRTANRLRTFTPEYVSCTFGAGGSTLSYTSETVRHLSQHH
GFDAAPHLSCVGGSRQEIRELLKLYRAIGCQRIVALRGDLPSGMGHPGDLRYAADLITFI
RAEHGDHFHLEIGAYPETHPQASNTLNDLHYFKAKADAGADAAITQYFYNPDAYFHFVDA
VQRLGVTIPIVAGVMPISNFDKLHHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVV
TALCERLIAGGAPGLHFYTLNLAKPSTQVLQRLGY
>A0A1A9LBF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aequorivita soesokkakensis|TrEMBL
MKVTEHIKNGNGKTQFSFEILPPLKGENIHSIFENIDPLMEFKPPYINVTYHREEYVFKE
LKDGLIEKKVVRKRPGTVGICAAIQNRYEVDAVPHILCGGFTKEETENFLIDLQFLGIDN
VMALRGDAVKSETYFTPEKNGHKYACDLVSQINALNKGTYLDDELQHTFPTDFCVGVAGY
AEKHMEAPSSESDIHFLKKKIKNGAEYIVTQMFFDNEKFFQFEKKCRAEGITVPIIPGLK
PIAVKSHLNLIPHRFKVDLPDSLVMEVVKAKDNKAVRQIGIDWCVKQSQELVKAGVPFLH
YYSMGKSSNIKEIASQVF
>A0A654L1X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain MDR-ZJ06)|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>H4FBW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PDO1-076|TrEMBL
MAEHQRAIEDAADLRISFEFFPPKSPDMEDQLWSTVEALAPWQPDFVSVTYGAGGTTREP
TLSTVKRLISDTPMPTASHLTCVGATRDEVRRVVEEFRAVGVRHFVALRGDPQDGVGAAY
QPHPEGFINAADLVGGLREMGDFEVSVSAYPEKHPESPDEAVDLDMLKRKVDAGATRALT
QFFFDNDVYARYLDRVLSAGITIPIVPGIMPIQNLTQLKRFASMCGASVPASIDRRFEGT
DCNAQDRAAVAADIAAEQIADLAKRGIRDFHIYTMNRAPLTIATLSRLGLDGKSRTLSGA
AA
>A0A3M1BGR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquificae bacterium|TrEMBL
MKIGEYLKQKGFSVSFEFFPPKTSEGEEELFQTIKSLQPLNPTFVSVTYGAGGSTRDRTR
RVVERIHRETDLTVMAHLTCIAHTKEELLQILEEYRHMGIENILALRGDVPANMPDFRPP
EGACRHSDELVRLIRESFGAWFSIGVASYPEGHPESPNMEWEIRYFRKKVEAGADFSITQ
MFFDNSFFYEFVELCSKEGIDIPIIPGIMPITNFRQIQRFASMCGATIPQSLVEKLEPYA
DNPEETFKIGVEFATEQCLDLLENGVQGLHFYTLNKSRATLLVYEGIKGALRA
>A0A5C1MFC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp. FeAm09|TrEMBL
MKIIDTMTPGKPFLSLEFFPPKERSEWPAFFRTVDRLNEVNPLFCSVTYGAGGSTHGDSL
EIVSRIKQEHGMETMAHLTCIGAHEGDVRSFLDQLARAGADNVLALRGDLPQDSTPESSP
HRPLLHASDLVALIRDSHPHVGLGVAAYPEVHPEAASTAADLAYLRLKLDRGADFAVTQL
FFDNRIYFDFIRNAREHGITKPIIPGILPVVSLKVIKRIVSLCGTVMPPEFLAQLEEADR
RGGAAEVQKLGVAHARRQAEDLLANGAPGVHLYTLNRADAVLEVTDGLRLR
>A0A659LXK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E2593|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A143ZHY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. 9140|TrEMBL
MSTRTLYPAERGDLRLSFEYFPPKSEEMDAQLTRTAAALNAYAPEFVSVTYGAGGSTKAR
SLTTVRRLIDDCAIPGTAAHLTCVGATRAEVDAVVEEFAAAGVRHFVALRGDPQGGIGAQ
YQPFPDGYENAAALVAALSRSGRFQISVSAYPEKHPESSDVDADIDMLKRKVDNGATRAL
TQFFFDNNDFERYLERVRKAGISIPVVPGILPINQFGQVSKFAGLCGARIPEALSARLAH
LDESPEERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFKRTDEAVVE
GAAA
>A0A520M172|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MHIRDIIEEGKPTISFEFFPPKTQQSSQALFQCIKELEELNPSFVSITYGAGGSTRELTH
ELVIRIKNSTSLIPVPHLTCVNHTEEDIFSILERYAKHEISNVLALRGDDPAEDASHDRS
LDSFEYASELVKYIQKFKESGHCKDQRGFGIGVAGFPEGHPETPNRILEMDYLKQKTDSG
ADYICTQLFFDNHDFYDFQERCRLSGINVPIIAGIMPVTSAKGLLRMAELAAGARIPGKL
LKAIDRCNGDAESIKRVGIQYATEQCSDLLNNSVDGIHFYTLNKSDATKGIFESLGLQR
>A0A511YIT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium hagamense|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYRNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTAGGHTSAMDLVYQINNLGRGKYLHNEEKECEELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKARDMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEDLINEVEHAKNNEAVKQIGIEWAIAQCRELLDFGVPVL
HFYSMGKSDNIKKVAGALF
>A0A0M2XUE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. Ag1|TrEMBL
MKIIDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTDGGHAFATDLLEQVTDMNKGKYLHEDIITSEKTDFCIGVAGY
PEKHFESPNFNTDFKYLKQKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVAACKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLA
>A0A2G9CG20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mitsuaria chitinivorans|TrEMBL
MTTPVSIEFFPPNTPVGTEKLKAVVQELRAVRPQYFSVTYGAGGSTREKTLSTVADIASQ
GFDAAPHLSCVGSTRENIAEILATYRAQDIRRVVALRGDLPSGTATAGEFRYAAELVRFI
RETQGEDWDIEVAAYPEYHPQQRYAARDLQFFADKVRAGASGAITQFFYNPDAYFHFVEA
SRALGVEVPIVPGIMPINNYARIAQFAQRDGIEIPRWVALKMEGYMDDAASVRAFGLDVV
TRLCERLIAGGVPGLHFYTLNQSALTLELCKRLGLAAEA
>A0A8J2U8B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neiella marina|TrEMBL
MSYHHAQHLGSLNESLADLSGDINVSFEFFPPKTEKMEQTLWSSVKRLAPLKPKFMSVTY
GAGGGERDRTHEIVKRIQNETGVASAPHLTCIDASRDELRGIADEYWNNGIRSIVALRGD
LPEGNPERPDMYAADLVELLKSQHDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANR
AITQFFFNVESYLRFRDRCLTAGIDVEIVPGILPVTNFTQLKRFADMTNVAVPQWMHTMY
DGLDEDQGTRNLLAASIAMDMVKVLRKEGVKDFHFYTLNRADLSYAICHTLGARPA
>A2A7F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mus musculus|TrEMBL
MVNEARGSGSPNPRSEGSSSGSESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFS
LEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPVGDHWEAEEGGFSYATDLVKH
IRTEFADYFDICVA
>A0A845S4G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Fonsibacter lacus|TrEMBL
MNKDLNISFEFFPAKDQTADESLWESFIKLEVFNPKFVSVTFGAGGGERDKSDYLVKKIK
MNSNTPVAGHLTCVDMSKDEINTIALDWLKNGINKIVALRGDVRKKDSKYKPHEKGYINA
ADMVKGLKKLGNFEIAVAGYPEKHPESKSEDEDLENLKIKVDQGADKIITQFFFNHEKFL
RFRDKSIALGIKIPIIPGILPIGNFKKVKDFSLKCGTSIPQWIEDKFSNLKEEEKFVGAE
LACDLINKLEAEGVNEFHFYTLNKYELSYAVCKNLINQKKAEKKEYNQNINQFFKNKEIY
I
>A0A7C1QS65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon|TrEMBL
MTEKMVYSKLGELIAKGEFVLTGELEPEKTCDLSHTIQEAREIAPYVVAANVTDSPLAIV
TINSMAASAIIQRETGLECVWQLTVRDANKIGLAGQIMGAEALGLSNVLSLTGDHTALGD
CPETKPVFDLDSATLIKLVREMVDTGSINGHEIEIPPKFHVGGAANPNADPMEAEILKIG
RKAEAGAEFLQTQVVYDIDMTAEFLREIKKYNVPILLGIFPMKSYGMAKGFDMFVPGVSV
PKEILERWKRVKTDVSDKKEQKEIYDQLNYEFFKPFIIELKSKGLITGVHCMAVKYTRFY
PKLIEVIKKL
>A0A151A3N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus kloosii|TrEMBL
MTQQLLDKLKNNILVADGAMGTILYSEGLDTCPEAYNLSHPERVERIHRTYIEAGADVIQ
TNTYGANFEKLKAFGLEHKVKDIHQAAVKIAKKAASQDTFILGTVGGFRGVRQEELSLSA
IQYHTEIQVDTLIEEGVDGLLFETYYDLEELTNIIQATRNKYDIPIIAQLTASNTNYLRD
GSKINDALQQVIDSGADVVGLNCHHGPHHMQQTFSHIELPEHAYLSCYPNASLLDLNNSE
FKYSDNAEYFGKVAEKLINEGVRLIGGCCGTTPEHIHYIKSSIKDLTPIHNKKVVPITKQ
SIATNSTTAKENLTAKVKRDATIIVELDTPKHLDTEKFFENIQKLDDAEIDAVTLADNSL
ATVRISNVAAASIIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILTITGDPSK
VGNLPGAMNVFDVNSKGLTEIAKRFNQGINTDGDALKKKTNFNIAGAFDPNVRKLDGAIR
RLEKKIDSGMDYFITQPIYSKEKIKTVYEATKHLGVPFFIGIMPITSYNNALFLHNEVPG
IKLSEDILTRFEAVKDDRDKTRELSIEICKELIDTVHEYFNGLYLITPFQRADLSLELAA
YSKSITSNSQEAIL
>A0A1X7KB09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWB13|TrEMBL
MKIIDILKQDKMSLSFEVFPPKKETSFENVKAATEAIAKLNPAFMSVTYGAGGGVSQYTL
EIAKNLKYNFNIPMLAHLTCISSTKETIHQRIEDMKAAGIKNVMALRGDLTPELIANGRG
DCDYHHAVELIRELKAADADFCIGAACYPEKHPESPNQAEDIKHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVDRAIKLSGSFMPQRFKSLVDKFGS
DPDAMKQAGIIYATDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFAG
>A0A2M8Y562|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 1|TrEMBL
MKVTQHIEKAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKAGGNNFAVDLVAQINQLNCGKYLHDVMDIDNKADFCIGVAGY
PEKHLESPSLMSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQKHLQILPQIFRIDLPEDLINAVEKCKNNAEIRQVGIEWAIQQSIELKAAGVPVLH
YYSMGKSENIRQIASQIF
>A0A174ZTE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] siraeum|TrEMBL
MKIKDLYTPGRTVFSLEVFPPNKNFPIETVYDAIEGLAAINPAYISVTYGAGGNRANRST
CEIASHIKEKYGIESMAHLTCINSTRDDVDFMLDDFAANGIENILALRGDNKPDEEPKND
FPHASDLTAYIASKGNFDIAGACYPETHVDAESAEEDIKNLKIKVDAGASHLVSQLFFDN
SCYYDFEKRARAAGIDVPIAAGIMPVTNKKQIERMVTLCGASLPSKFVKMMQKYENDPEA
LRSAGIAYAIDQIVDLISNDVQGIHLYAMNNPAVASRIYNGIKDLL
>A0A391NXU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mediterraneibacter butyricigenes|TrEMBL
MKISEKLNSGKINISLEVFPPKTSDTYDKVQDAVDKIGALKPAFISVTYGAGGGTSKNTL
KIAKHIKDDLGVDSLAHLTCASSTKEEVREVIGRLKEAGIENILALRGDIPEGGSLPGDD
SFKHASELVQEIKKHGDFCIGGACYPEGHVENAHKEDDIRYLKEKVDCGVDFLTTQMFFD
NSIHYNFLYRIREAGITVPVLPGIMPVTNGRQMKRICQLSGTILPARFQAIVDRFGDNPA
AMQQAGIAYATDQIIDLLANGIKNIHIYSMNKPEVAAAILNNLSEIVKC
>A0A1B8WVD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera sp. DISK 18|TrEMBL
MHTHELFAKKTVFSFEVFPPKRDTPIETVYPTLDELSKIHPDFISVTCGAGGNGGNRTTE
VATYIKNLGCETVAHMPCIYLTEEDALKTLQELKARGIENILALRGDETPGRERTHRFEH
ASDLIAFIKDKAPEFNIIGACYPEGHAEAKTVAADIRNLKTKVDAGASELISQMFFDNAV
FYRFLERCEIAGIKVPIEAGIMPVTNKRQIENMIAMCGATLPIKFQRAIAKYGDKPDAMY
DIGITYAIDQIADLLANGVDGIHVYTMNNPDIAKRISDAVKNLL
>A0A4U8SY56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter magdeburgensis|TrEMBL
MFGIEFLPQEICEDMECLKAMIQGARENLGQEVDFVLIPSNPVNKASVSSLLGAYALRER
FSMSVDSGFSSVVEFVPTISGAGLDRLQIQSQILGVKYGGFSSVALIGGDNGELDGVKLI
ALAREILGGEVSLVSGSGVKIWEKEIEQRLTQKLQAGVDRIITQPIFSMESAKKCVEHFY
VLQERLGIQAQLSLGVFGIFSAESAYRINETHLGFEIPRAYLKALEQSGVKETFISLWQD
MQGLAREYDISLYLSTPKHNDLRAYGNGLC
>A7IJ78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)|TrEMBL
MTTPALAPAPAPVRASREMDRPPVKVSFEFFPPKSPEMEKTLWSSIARLAPLSPDFVSVT
YGAGGSTRERTHATVERIAKETDLAPAAHLTCVAATRDEIDAVVRAYGEAGVKHIVALRG
DPVTGVGTRYEPHPGGYAYANDLVAGIKRIGDFEVSVSAYPEKHPESASLDADIDVLKAK
VDAGATRAITQFFFENDVYFRYLDKVRARGIDIPIVPGILPVTNFKQASSFATRTGASVP
AWLLRRFEGLDDDVETRKLIAAAVAAEQVTDLVDRGVTDIHFYTLNRADLVYAICHLLGL
RPKVAGALADAPKAVAI
>A0A0P7WXB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium HLUCCA12|TrEMBL
MALFNFARRDSGPVRGSAALTTLLQGFSIEVMPRTAEKVEDFRALLPVGTRVYIAHIDGT
PIDEMVATARRLRNEGFEPMPHFPARIIPDKAVLTDWVARYRGEADVRQGLILAGGSAQP
VGDFHSSMQLLETGAFDGFERLHVAGHPEGNKDIDPDGSDRMVMEALRWKQAFSQRTDAT
MALATQFCFDAQPVIDWVDRLNAEGIALPVHIGVAGPAKLQTLIRFAVACGVGPSLKVLQ
KRAMDVSKLLLPYEPDPVLEALAARKAANPDFGIESVHFFPLGGIKATAEWTQRHGQRPV
RAAA
>A0A4P6GM18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ACM7|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A4U8SZ43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter magdeburgensis|TrEMBL
MLDQLITKLHSNQAFLSVEVSPSLSSTIGQSVIDELKSLKQADCFVCTDSPLARLKPSSI
LTSIKLQNALKKPVICTFSMRDRNSIALCGDILGANEFGLRSFLSLSGDGVKNGDCVGAK
GVFEESSLKLGRIIDGLNQGIAANGKVLKDSVETIYNFSVINSYANNTESLKKKMLKKLS
NSAVQGLFTQPVFSLEAARFLLESMESINKELGQNCVMILGFFPVLSYKVALFLRDKLPG
VYIPNEWVQKLEKASIKGKEVERKIGLELSRELFKDLQALHNKFHFMSANKPSLLREFV
>A0A1L8FFK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenopus laevis|TrEMBL
MWNSGPLAVRNCGLRMVNANSSDSGTASCSSEENSKESSRCSTPVLDIERHERLKDKMKR
RIEAGDRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMV
IASTAVNFCGLESILHMTCCTQTKEDITKHLQKAKHLGLKNIMALRGDPTGEEWEEEAEG
FNYAVDLVKHIRHEFDDYFDICVAGYPKGHPEADSYDQDLKHLKEKIDAGADFIITQLFF
RSETFLTFLKDCRAIGITCPVLPGIFPIQGYGSLRQLVKLSKLEVPQEIMDIIEPIKDND
AAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDVLKRLGMWKEDPRRPMPWAM
SAHPKRRVEDVRPIFWASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGDLKDYYLFYLKSK
SPREELLKMWGQELTSEESVFEVFTHYISGEPNPNGHKVTCLPWNDDPLAPETNLLKNEL
QKVNKRGILTINSQPNVNGKPSTDPIMGWGPSRGYVFQKAYLEFFTSSEMVSALIKVLKR
YEPRMNYHIVNVHGKNITNAADLQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALW
IEQWAKFYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVIEDTFKEHDSPTDQ
>A0A7W6WYD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. cir1|TrEMBL
MTDLTTPATADRQDGQLKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILRETTLLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPAG
GIGTPYSSHPEGYQSSAELVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDDDPETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A368NHC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium vitis|TrEMBL
MAHTSSNRDQARPFKLSFEFFPPKSEEMEAQLWATVDELTGWEPEFVSVTYGAGGTTKAP
TLAAVRRLLAETPLATASHLTCVGATREEIAQVVEDFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGFENAAALVKGLKELGDFEISVSAYPEKHPESADLAMDLDMLKRKVDNGATRALT
QFFFDNDIFERYLDKVRAAGINIPIVPGIMPILNLTQLKRFAGMCGTSVPAMLDQRFEGL
DDKPTERASVAAALAAEQIADLQGRGIDEFHIYTMNRAPLVNATLERLGLQRSDTVAAGR
AGVIA
>A0A7S6M7B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetia bacterium|TrEMBL
MRIRELLSTGRPSISFEFFPPKDEAGIEALKTTIASLRELRPTYVSVTYGAGGSTRDRTI
DLVGQIRREFGIEAMAHLTCVGSSKEELRGVLARLAACGVENVLALRGDPPKGDATFTPH
PEGFRYASELAGFVRSGYRFCLAGACYPEKHVEASSFDADLDHLRRKVDAGCEFLITQLF
FDNQRYFDFVARARAAGIGVPIIPGIMPITNVAQVERFTQMCGASIPELLLRELRGLAGD
PAAVTAQGVAHATAQCLELLQRGAPGIHFYTLNKSPSARTILTAIRTVYPPARTPAGSWD
>A0A6N6Z589|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceicoccaceae bacterium 5H|TrEMBL
MNRGRAISDILEAKDHPLLSVEFFPPKDDAGGDLIVQTALDLKQQVQPDFVSITYGAGGT
TQERTYRYARILRDKYGFEVMPHFTCVGNSKAEVIDLVGQYWKDGFSNLMTLRGDPPKGE
TDFKPHPDGCHYASELVELLHENFPDLCMGVAAYPEVHPQAVSPEDDLKYLKRKVDNGAS
FATTQLFFDNRNYFAFVDKARALGIDAPIIPGLMPIRSAKQARRFCDHIPEELDDMLNKA
GDDKAAIHRVGVEWCFRQIQELLEGGAPGVHLYIMNRSKMAIELANRLREAGLWQPAATV
>A0A7G7T0S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. GW|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKTYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQASDALSDLRHFKAKVDAGADGAITQYFYNADAYFHFVDA
VRKLGVHIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQALGDDADAIREFGADLV
AALCERLLAGGAPSLHFYTLNLAKPTVGVLSRLA
>A0A7W0YRY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
MGTMLYSKGIFINQCYDELNLRAPDLVRDVHRAYVKAGAEVLETNSFGANRTKLSQYGLE
SQVGELNLRAAQIAREAAGDGVWVAGAVGPLGLRIEPYGPTSRDEARAHFGEQMRALREG
GADLFLLETFGDLDEIEQALLAARDVDPSLPVIAQMTIGNDCHTPYGANAADVARTLDAW
GADVIGLNCSVGPQIILEAIERMTPVTRRKLSAQPNAGMPRDVGGRTMYMASPEYMASYA
RHLIQAGARIIGGCCGTTPEHIRAVAQGIRSLLPRHGRPSFTTGATRARKSPPSIDATDV
PAPGGVEPVPFAERSRWSQKIAAGEFVTSVEIVPPRGVDATKMLSGVRALKVAGVDAVNV
PDGPRAQSRMGALLTSVLIEQQIGIESVTHYCCRDRNLLGMLSDLLGASAIGLRNMLLIT
GDPPKMGPYPDATAVFDIDAIGLTNLVSRLNRGLDPGGNAIGSPTRFSIGVGVNPGAIDP
EHEIRRFEWKVEAGAEWAITQPVFDVEQLERFLERIAHVRIPIIAGIWPLVSARNAEFLA
NEVPGVVVPQAIIDRMRQSNAVSKDRAVQEGIAIAREMLARVRESVQGAQVSAPFGKVEL
ALEVFGKRETGNGGLEAGGLLSAATGPS
>A0A4U6XQ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum tanaceti|TrEMBL
MHIKSMLDETRRSGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREHEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGATF
IVTQMFYDGDNFVRWVGKVRERGINVPIIPGIMPIATYASFIRRAKHMNCKVPDDWMAAL
EPIKNDDVAVREVGKGLVADMCRKIVAAGIHHLHFYTMNLAQATRMVLEELNWMPTSDRP
VKHALPWKQSLAHGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPRSIKDVANIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSTHPVHGWGPANGYVYQKAYLELLVHPDAYAEIVSRVEKNP
DMTYYATTKNGSLKYNATHDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGIDW
AHCFEAGTPSRVLIERIMNEWYLINIVNNDFHQKTALFDMLEGLEVKEYADIPAEPQTNG
AAETNGNSVSAAAN
>A0A1H5LIM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiangella alba|TrEMBL
MPGGARTIRELLAAGGRSFSFEFFAPKSETAEVSFWQTMRDLERLQPTFVSVTYGAGGTT
REGTVRLTEGIARDTTLTVVGHLAAVGHSVAELRNVIGQYADAGVRNFLALRGDPPGNPQ
GEWVQHPEGFAYAEELVRLIRTHGDFCVGVAAFPDKHPRSPDLETDARFLARKFQAGADY
AITQMFFHADDYLRLRDRVAAAGGAAPIIPGIMPVTNVRQIQRFAQLTAADFPEPLARRL
LAVEDDPEAVRAIGVEVATELCERLLAEGVPGLHFITLNKSTATREIYQNLGVGALS
>A0A1Y2WAR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypoxylon sp. CI-4A|TrEMBL
MEKITDKIAGLPAGSNYFSLEFFPPKTPMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
ATKSLELAEICQRELNLTTCLHLTCTNMSRKLIDRALEDAKALGIRNILALRGDPPRAAE
YQDPNESPEDAIDETFTWAIDLVRYIKKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDI
PYLVEKTLAGADFLMTQLFFDTDAYDKFEQTLRNHPSGAFKTIPIIPGLMPIQSYQMINR
TTKLSHASIPDSIMSRLDAVKMDDEKVKTMGVDILSEIVEKIKDITSRTPGPTGFHFYTL
NLEKAVSFIVEKTNLIPPSTPIEEEAVVEEITSKIPTLQVNGSDHDHVPKPREDSRSRRQ
SNVSSEHRNRVIVSGRPVSHPEYEATSAEASIPAEPINSRANTLAISEGEGVLGREATWD
DFPNGRWGDARSPAYGEIDGYGPSLHVSHAQAVSLWGYPKKLEDINALFVRHLKGQLPAI
PWSEEEFNEETGIIAEQLVQLNSKGWWTVASQPAVNGLRSSDPIFGWGPQHGFVFQKAFV
EFFIPSAEWKVLLEKLQSSEVQDTVCFYAANAAGDFVSSDMTGGLDGKVKEPSTNAVTWG
VFPGKEIITPTIIEEVSFRAWSEEAFGIFGEWAQVYGKGSESEKVLENARKDSWLVNIIR
HDYVDKDALWNLLLH
>A0A1J5HYJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium CG2_30_58_14|TrEMBL
MKSGSNLEKVFVNGHFAVTAELGPPKNNDVSVIQRKVDFLRGYVDAVNITDNQTAIVRMS
SIATSAFVIQMGMEPVMQMVTRDRNRIAMQSDLFGATALGIKNIVCLTGDHHTFGNQVNA
KNVHDLDSVQLINLVKTMRDEKTLMGGEEKFEGDIKLFIGGAANPFADPFEFRALRTAKK
AAAGVDFIQTQCIYDMERFKEWMKMIRDLGVHEKVHIMAGITPLKSAGMARYMAKNVAGI
TIPDAIIDRMAKAAKGSEEGIKICVEQIQEVREIEGVHGVHIMAIEWEQMISKITEMAGL
LPRPKVE
>A0A5B8JIJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. UKPF54-2|TrEMBL
MSPPSLIDAHPNLAGAAPLALSYELFPPRSPAAAESLWTTIAELEATSPDYVSVTYGASG
SNRGTAVELVRRLVQETSLRPLAHLTCVGNTPQELAEVIGELLDVGVRGILALRGDQPRD
GERPAQGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYAQLLARARRAGVTIPIVPGVMPLTSIRRLTRLGELTGVE
PAPELIEKLSAAGTDAERNRIGVAATVDLANAALDAGAPGLHLYTFNEHASALDVLDKLA
LPRPHRAGGRAGAARRGAGQQLAS
>A0A3N2GNH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis thermoflava|TrEMBL
MSHSGRLADLVRAMSYEVMPFASTERKVLEHVPVTVPLTVTVTEAKGLDTTLDLTERLLG
HGYRATPHLAARLFRDDRHVADVASRLREAGTDSVFVVGGDAPAPAGPYPDAYALLQALE
RTGHSFRAIGIGGYPEGHGVIPQEAVDLALKQKAPLATRILTQICFTAATTHAWAERIAA
SGIDLPVHVGIPGPVNRQKLIRISAGLGLGQSARFLRKQQNLLWRFLLPGAYQPGKLARR
LASRPAGNIRGLHIFTFNELEGTERWRQGLLASLGTRDGRS
>D5MF95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methylomirabilis oxyfera|TrEMBL
MKIVDMYSTGKFGLSFEIFPPKTEAGEAQLFSALEALMVFRPSFVSCTYGAAGSTQEHTL
ELTVKIRKACGVTTVAHRTCVGSTAGGIRQWLKEATDLGIENIVALRGDPPKGQTEFKKP
EGGLAYANELVALIRQEFPHFSIAVAGYPETHQEAPSPAVDLANLKRKVNAGADAVITQL
FYDNRDFFDFRSRCVEAGITAPLIPGILPVVNLGQIQRITSMCGAKIPASFLAELETYRD
DPDGQAGAGVRFAIRQCRELLDAGIPGLHFYLLNKAEATFRILEALKLSG
>W1NAS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas huangheensis|TrEMBL
MNDINRAALAAALESSTRLAIRFELLPISGLREAARELPEGAVVTVTCSPRHGLERTLEA
AEWLVGSGFRVVPHLAARLVRNHDHLQRLLQHVAMLGIEDVFVVGGDVPRAVGDYPHGLA
LLEDMARLALRPVRIGVPAYPEGHHHIEPPCLQHDLEAKATFADYAVTQLCFEARPLLDW
RDRQTRLGLRLPVYAGIPGVIERKRLLGIALRLGIGSSVKSLRRQSGRMSRLFGPSAYRP
DALVDELGAVLGASDSGFAGLHVYTFNQVADTRTWLEKLEGRQRTASPEAESVPGK
>U2FQE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. AU4i|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLMPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLVDAGVPGLHFYTLNTAAATRTICERLDV
>A0A1W9LKE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium A6|TrEMBL
MKSGSNLEKILTAGHFAFTGELGPPRGTDADEVRKKASHLKGMVDAVNITDNQTAVVRMS
SWAASIIILQEGLEPNYQMVCRDRNRLAMQSDILGAYAHGIRNMLCLSGDHQKFGDHPQA
KGVFDIDSMQLIGMVKRMRDEGKFLGGTEIGHPPKIFIGAAANPFADPFEWRVHRLAKKI
KAGVDFIQTQCIYNMEKFRTWVKQANEMGLTEKVYLLAGVTPMKSVGMAKYMKNNVPGMD
VPDELIKRLQGVDKKLQADEGIKIACEQIEEFKQMKGVAGVHLMAIEWEHKVPEIAERAK
MLPRPVIGSNIES
>A0A4P5XVC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetia bacterium|TrEMBL
MLIRDNYGPGKFGLSIEIFPPKTAAADAALFESLDRLTAFQPGFVSCTYGAGGSTSKRTV
ELCVEIQKRYGLTATSHFTCVGATRDELLDWLKFARQSGLQNIMALRGDPPAGQTDFQPV
AGGLRNANQLVALIREHFPDMGIGVAGYPEKHPEASDADTDLNNLKRKVDAGADAIFTQL
FFVNDNFFRFRDRCEAAGIRVPIVPGIMPVTEFARIKRITSLCGAVFPTELASRLEAVQT
DEAAQFQIGVEWAIRQCRELVSRGVPGLHFYALNKSPACEAILNEIRD
>A0A654A3Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 9AZ|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVKVPTAPHLSCVGDSKAELRELLNLYKSSGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADCYFY
FVDRVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTDSIQAYG
EQVITEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A7T0RU58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio navarrensis|TrEMBL
MGYTHASHIGALNQNIAELSDNINVSFEFFPPSTPQMEETLWSSVQRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAQTGLVAAPHLTCIDANRDELINIANDYWANGIKNIVALRGD
IPPSGGAPEMYASDLVTLLKSLHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDDDPVTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKQA
>A0A6M1QQM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. KC13|TrEMBL
MSRRSAATVVRRLLLAARYEVLPTDAIEKVVTAALPAGRTITVTASPAKGLERTVDLSIR
LAGHGYDVVPHLAARMVSSRAELADITGRLKAAGIEKVFVPAGDAEQPGAFPGALELLEA
LVDLGDPFRHVGVAGYPEDHPTIIHDRLVQAMWDKRHHATEIVSNLTFDDRALTDWVRRV
RARGVTTPILVGLPGPVERTKLLSMATKIGVGESTRFLAKNKGMFARIAAPGGYSPERFL
TRAGPGLDGAEAAVAGLHLFTFNQVAETEAWRRDLLTRLGGDPL
>A0A7H8LDJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces seoulensis|TrEMBL
MALGTASTRTDRARTVRDMLAAGKSTFSFEFWAPKTEKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRSGTVRATQQIAADSTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGNWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVTAAGCATPVIPEIMPVTSVKMLERLPQLSNAVI
PDALKERILAAKDDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A7W0UAL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MRIDQILEERRPCFSFEFFPPKDDEGMERLFNTVSELQEDDPAFVSVTYGAAGSTRDRTL
GVVRRIRQETDIEAMAH
>A0A8F8JAF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. B230/85|TrEMBL
MTSTPDTGRSDVSISFEFFPPKTPDMEGQLWAAITELTEWQPEFVSVTYGAGGSTKAPTL
NTVRRMIAETPLPTASHLTCVSATREDTHRVVDELRAAGVRHFVALRGDPPGGIGTAYQP
HPGGYENAAALVAGLRDIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDVFETYMERVRAAGIAIPVLPGIMPIQNLTQLKRFAGMCGTSIPSYLDERFAGLDD
KPEERAKVAADVAAEQIEDLVRRGHREFHLYTMNRAPLVGAVLERLGFKRTKIAAAAGAA
A
>A0A7G6B235|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum frisingense|TrEMBL
MSTHNFSIEFFPPKTAEGAQKLRATRARLAQLQPRYFSVTFGAGGSTQQGTRDTVLEIIG
EGHQAAPHLSCIGSSRASLRAILDDYRTNGIKRLVTLRGDLPSGYGAMDQASSEFRYANE
LVEFVRAETGDWFHIEVAAYPEMHPQARSPQDDVQNFARKVKAGANAAITQYFYNADAYF
RFVDEAARLGATVPVIAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTESIRAF
GQDVVKQLCERLLAGGAPGLHFYSLNQAAPTEAIWQQLVK
>A0A137RGD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aequorivita aquimaris|TrEMBL
MKVTDHIKNGNGKTQFSFEILPPLKGENIHSIFENIDPLMDFNPPYINVTYHREEYVFKE
LDNGLIEKKIVRKRPGTVGICAAIQNRYEVDAVPHILCGGFSKEETENFLIDLQFLGIDN
VMALRGDAVKSETYFTPEKNGHKYACDLVLQINALNKGTYLDDELQHTFPTDFCVGVAGY
PEKHMEAPSSESDIHFLKKKIKNGAEYIVTQMFFDNEKYFKFVEKCRAEGITVPIIPGLK
PIAVKSHLNLIPHRFKVDLPDALVMEVVKARDNKAVRQIGIDWCVQQSKELVKAGVPFLH
YYSMGKSSNIKEIASQIF
>A0A1R4HPZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter sp. 7(1)|TrEMBL
MTPTLLTGSAPTRARFSFEVFPARSGAAALALGHAVQHLSAAGPDFISVTYGANGSNRDA
SVDLLRYLRDHTDALPLAHLTTVGEDRDTVRAAIHGIMDAGVHDFLALRGDPPRGLTEDS
PEVSGSLSARDLVELIAEARAERPALTSVGRTAVAAYPNGHPLARSRAADIEWLIAKEEA
GAQFAITQLFFRAEEYLSFVSDAHDAGLRMPVLPGLMPVATSAQLRKVAELAGRPAPVEL
TRELEEAGGYAPELGVEHTVELARELLAGGAPSLHLYTFNRHERVLAVLRELHLLTPDPV
V
>A0A4P6TTV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces seoulensis|TrEMBL
MALGTASTRTDRARTVRDILATGKTAYSFEFYAPKTPQGERNLWNALRRVEAVAPDFVSV
TYGAGGTTRATTVKETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVSAAGCETPVIPEILPVTSVKMLERLPKLSNALF
PSELKERILSAKHDPAAVRSLGIDFTTEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A5J6PSR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria zalophi|TrEMBL
MTSTHKRLSFEFFPTRTPEGRAKQVITRKQLSQFSPEFFSCTSGAGGSTKEGTMQTIKDI
LSEGVAAAPHLPCVGMHPQELIDLLNEYKALGVRHIVALRGDIPSGMGGGLSGLRYANEL
VSLIKEEFNDDFYIEVAAYPEYHPQARSAEDDLNNFVRKAKAGADSAITQYFYNADSYFR
FVDDVRGRGVDIPIIPGIMPIASFSKLARFSDTCGAEIPRWLRLKLQSYADDTASIKALA
LDVVTEMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>A0A537D6B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MAASGSSTNPMSFPASEIDVSARAGSVAELVAAGSIEISPRELHRAAEVAALVPAGTCAY
VPSLPGLPVSRVLETVAAIRRAGLDPVPHLAARRSAGREQLREFLRRAAGEHGVHRVLLV
GGDQPRASGPYSDTLQVLEEGVLADTGIREIGIAGYPEGHPRIAPAALEEAFARKQRLAA
EQGLGVYVVTQFCFAPARVVECCAALARSAPSVSIYVGVAGPTDPAALLRYAQRCGVSAS
LRALRNLGTGIAQLVTHTDP
>A0A536XHC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MSPKRERVFSFEFFPPATPEGAQKLAATREQLALLAPKFFSVTFGAGGSTRDRTLSAVLE
IQAAGHRAAPHISCIGSSRASIRETLRNYREHGIRHLVALRGDLPSGSADVGEFRYAYEL
VEFIRAETGDAFQIEVACYPEYHPQAANPDADLANFKRKIDAGADSAITQYFFNADSYYH
LVDRAHKMGIDVPIVPGVMPILSFSKIARFSDACGAEIPRWIRRRMESFGDDSASIRAFG
VDVVTQLCADLLARGAPGLHFYTLNQAALSITIWQRLGLPMGQP
>A0A537ACJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MEPHFGTRFVRPSPEDEHRNIQVLLAGASLELSTRDPAEIDACAGVLEPGTAVYISMPPG
QTYHGTVALATRLRRAGFYPVPHVAARRIASRDALDEYLARAVGEAGVDSALVIGGDSDR
PSGPFDSSRTLLETGLFQRHGVVRIGVAGYPEGHPKIAATALETALAAKKSLARRAGLDL
QVVTQFCFESEPVLVWAAKMKGHGLPVRVGLSGPASLPRLLRFAALCGIGNSVRALKARP
RVITRLLVEAGPEEVVRDIARRSASPIAGVHFFCFGGLIRTARWLRAVREGRFELTGDGS
FRVGAA
>A0A536SPR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MDLATKEESSTDAASELQRQLRGGRFVVTAELTPPVSSDPAEFIDQALALRGLATAVNVT
DGAGSRAHLSSLAASHFLMRNGIEPILQLTCRDRNRIALQGELLGAAALGIRNVLALRGD
DPKTGDQPDTKAVFDLDTTGLLAMAHRMRSEHRLPSGTEIKGVLKFVLGAAEIPVDPPAG
WRPDGLLSKADAGADFIQTQFCMDAGVVRRYAARLLDLGIAQRLPILIGVAPIPSVRSAR
WMKEKLYGALIPEDIVTRLERAADSKSEGKKICIELMRELAETPGIAGAHVMAPQNHAAL
AEVIADSGVRGRKRAPAKHP
>A0A180EHB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lewinella sp. 4G2|TrEMBL
MRVTDYIDQAKGKTLISFEVLPPLKGGSMQAIFDTLDPLMEFKPPFIDVTYHREEYVYKK
RASGYYEKTAIRKRPGTVGICAAIMHRYGVDAVPHMLCGGFTKQETENALIDLGFLDVQN
VLALRGDARKFEGKFVPEKEGHHYASDLVGQIAQMNEGQYMDDLTDQSNKTNFCIGVAGY
PEKHFEAPNMEIDLRFVKKKIEAGANYIVTQMFFDNQKYFDYVDACRAAGINVPIVPGLK
PITKLYQLNSIPRLFHVDLPDDLVKAITEAKDAKARTQAGIEWCIAQSKELKERGAPVLH
YYTMGDSSTIRSIAEAVY
>A0A536X0H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MSFPASATEPGIEARASELVAAGSVEISPRELHRATEVAALLPAGSCVYIPSLAGLPLAR
TLEAIAAIRAAGLDPVPHVSARRIVNREEFRDFLRRAAAEHGVHRVLLIGGDEPRPKGPF
VDSLQVLEERLLADCGVREIGLAGYPEGHPRIPLNAIEAALARKLELAASQSIGVYVLTQ
FSFAPARVVEYCVMLARRWPSLPVYVGIAGPTDPAALARYAQRCGVSRSLRALRTLGSGI
AQLVTNTDPRDQVVTVARYTRSREPSNVVGVHLYSFGGAVRTAAWMRELL
>A0A4R7VER3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas helmanticensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A374DIB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM36-18|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGIESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAYGVDGIHLYTMNNPYVARKITEAVSSLL
>D7K4W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. 3_1_23|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEIAKIIY
>A0A221NVX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces pluripotens|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFYAPKTPTGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRATTVKETQQIVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWIPHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSRNWDSDVSHFVD
KCRAGADYAITQMFFQAESYLRLRDRVVSAGCDTPVIPEVLPVTSVKMLERLPKLSNAHV
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A4P5QJU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buttiauxella sp. A111|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRGIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNYNQAHKFATMTNVRVPHWMAQMFE
GLDNDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPTV
>A0A0U4H1G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. XT11|TrEMBL
MSLETPTTRVPFSFELYPPRSASSEGALHETVRRLAAAGPDFISVTYGAGGSTGGRSLEV
LRFIREHTDVEPLAHITCVGNTYAGAAALIREFLDAGILSFLALRGAPPAGQEEPFLGDL
ESAAQLVQLIDRVQAERAPYEETPVPGLPGAARVAPRRRASIAVAAFPNGHPRSAHRWQD
VDALLAKQAAGATSAITQLFFHADDYLAFVERARSAGVTIPILPGIMPIVSPVRLARVLE
LTGEELPGELAIALDVEPTPEGRREIGIQWAARLAREVLAGGAPGVHLYAFNQHDTVLTV
LEEAGVLPVPSSH
>A0A1C4JFU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Termitarium-T10T-6|TrEMBL
MRHPGLPAILPVTDPRQIVRFAELSGVVFPGDPARRLHAAGGGGEGRRTGVDFAVAMAEK
LLTEGVPGPRYITLNRSSPTSEIHRALLGSALTAHA
>I2KA72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp. AR|TrEMBL
MFEKFCDILCNDKKFITVEINPPHGASIDGIIADIKKHDLQNKVTGFSCTDNPLAKLKMS
GVLSAIKVQQTFEKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKYSDQPE
VKGVLERDSTLLLSIIYHLNKGVDYSNKPLNPAPKPIYPFAVSNATAKDMNSLKKRMIKK
LNYGARAIITQPVYTLENAKELLALFEEAKALSIRDTAKEAQLVLGQFPIVRAKTANFID
DKVPGISVPKDIIDEMNLAAMDGEEREQEVGFALSKRIFDEMMDIHGKVHLMTHNRFDLC
SQLIG
>A0A1I3CUV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas ruminantium|TrEMBL
MKRVSVELVPRDEETLRAELALLQQYQDKIDVINIPDLLRFETRSWQGAAMAKEYFPDAM
PHIRAMDINLEEELPMKDYLRAHDIREVLVIEGDPPQRMTHAVYPTESTDVIRKFREEMP
EVTVYAGIDQYRSSMRHELYRIHRKVQAGAKGFFTQPFYDRRLLEIYADMLSGLEVYWGV
SPVMNAGSQSYWERKNNVVFPQAFEPSLEWSVQFSREVMELADKMDASLYLMPIRTNLEE
YLAGVFR
>A0A351I0Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MDIPELLAATERPLFSFEFFLPKAPEDLDAFVAFVRELKDLSPDYVTLTYGAGGSARERT
IEIAGRLQRETGLTTVSHLTCIAHTRAEISAILLRLEALGIRHIVALRGDAPKDAALRPV
EERDFAHAVDLVRHLRERGGLRTAVAAYPEKHPESPSPEEDLRRFAEKVAAGGDWAVTQL
FFDARDYFAFVRRAREAGVKVPIVPGIMPVTGYPQLKRFVGLCGARIPPELDERLSAIQH
DSQAVVAFGVDWAVRQCRALLDGGAPGIHFYTLNRSHSTAEILSRLRRP
>A0A266QCY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrio mixtus|TrEMBL
MNDSQPRLSFEFFPPKTPEGKEKLIKVRDQLNEFAPDFFSVTYGAGGSTRDNTKGIVTQF
KADGISIAPHLSFGGDDEVTIKSLIQEYKDAGVDRIVALRGDMPSGVGGAYQLVYANELV
AFIRNHFGEHFHLEVAAYPEIHPQAKSYSDDVRYLKGKFDAGANSAITQYFFNPDSYFYF
IDQCQKAGITQPIYPGIMPIINYKNLTRFSDVCGADIPRWLRKALENYGDDEASLKAFGV
ELVTDLCDTLLENGAPGLHFYTMNQTEPTAEIVRNLGLIPTDD
>A0A0D1M563|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas melonis|TrEMBL
MTISVNQLEEAQIALKAPLYADVGGHLDVSFEFFPPKTEKMDEQLWEAVRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATRAEIDQVAEDYWAAGVRHIVA
LRGDPPAAGAKFESHPGGYENAAALVAGLKRLHPFEISVAAYPECHPDSVSVAADLDNLK
AKIDAGATRAITQFFHEPETFFRYRDKVAAAGITAEIVPGIMPVTNFASVVRMSKMCGTE
VPAWLARLFDGLEDHPAARQLVAATLAAELSRKLYAGGCKSLHFYTLNKAELSFAICHLL
GVRAKPMQDAAAA
>A7H2H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IQKQGEFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKPKAAIKIYEAVKHLLKEELRA
>A0A7Z8D9G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKNNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPKKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDNAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A7Y9FLQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas melonis|TrEMBL
MTISVNQLEEAQIALKAPLYADVAGDIDVSFEFFPPKNEKMEEQLWDAVRTLEPLAPSFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATREEIDQVAEEYWAAGVRHIVA
LRGDPPAAGAKFASHPGGYENAAALVAGLKRLHPFEISVAAYPECHPDSPDMAADIDNLK
RKFDAGATRAITQFFHEPETFFRYRDQVAAAGIDAEIVPGIMPVTNFASVVRMSKMCGTE
VPAWMARLFDGLEDHPASRQLVAATLAAELSRKLYAGGVKSLHFYTLNRAELAFAICHLL
GVRSKPVANVAAA
>A0A1A9I988|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niabella ginsenosidivorans|TrEMBL
MKVIDHINNAKETLISFEILPPLKGKGIQALYDHLDPLMEFKPAFINVTYHRSEHIFKKN
PDGSFKKVEIRKRPGTESICAAIMNKYNVDTVPHLICGGFSVNETEDALINLNYLGIDNV
LVLRGDAAKSETAFIPQPDGHKYASELLKQVVNLNNGIYQEEDLKNTQKTNFCIGVAGYP
EKHFEAPNMDTDLAYLKQKVDGGADYIVTQMFFDNAKYYAFVAACRKAGINVPIIPGLKP
IYSLKQMNVLPKTFHIDLPTELSKEIMQCKTNEAVEKVGEEWLLMQSKDLKKNGVQVLHY
YTLGKPQIVSNVVKQL
>I1SKU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces flavogriseus|TrEMBL
MRDLRDVLAAGEKSFSFEFFPPKTDAGEERLWDAIRRIEALAPAFVSVTYGAGGSSRDRT
VAVTKKIAAQTTLRPVAHLTAVGHSVAELRHIVGQYADAGIRDVLALRGDPPGDPGGRWD
AHPRGFTHAHELVSLIRELGDFSVGVAAFPERHPRSADWDSDIRHFVAKCRAGADYAITQ
MFFRVEDYLRLRDRVTAAGCATPIIPEIMPATDVKQIRRFAELSDAAFPDDLAHRLEAAR
HDPAEGRRIGVEYATVMAERLLAEGAPGLHYITLNQSTATLEIHQNIQNSRSAHALAADR
>A0A1V9ETF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niastella yeongjuensis|TrEMBL
MKVIDHIRQAKDSLISFEILPPLKGKTINSIYEHLDPLMEFKPAFINVTYHRSEHVFKKK
ADSTFEKVEVRKRPGTVGICAALMNHYRVDAVPHLICGGFNKRETEDALIDLNFIGVDNV
LVLRGDAAKNETVFEPEKGGNSYAIDLLKQVQNLNTGIYLEEDIRDGFKTDFCCGVAGYP
EKHFEAPNLQTDLAFLKAKVAAGAEYVVTQMFFDNQKYFDFVKRCRENGITIPIIPGLKP
ITSKKQLSVIPRTFHVDIPDDLANEIMNCKTDADVEKVGTEWLLLQSKELKKAGVPVLHY
YTLGKPKVIYNVVKEIK
>A0A4R2RZ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heliophilum fasciatum|TrEMBL
MTRIAVELVPRNEQTLLEELQVIHTHYPTVNVINIPDLLRFDLRSWEGCCIAKRFFTSAI
PHLRAIDFNLNEPLPVVPYLRAAQITEVLVLQGDPPQGMERKVYPSTSIELIRKLKEEMP
ELRVYGAIDQYRTSMRQELNYIKRKIAAGADGFFTQPFFDLRFMEMYMDALQGQEVFWGV
SPVLGEKSVNYWETKNNVVFPARFQPTLEWNIGFAREALALAGSAASPIYFMPIRMDMQT
YLGGVLKD
>A0A1M7RUY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio hungatei DSM 14810|TrEMBL
MKIIDILNSKDVTLSFEVFPPKTDAGYAAVEKAAAEIAALKPDFMSVTYGAGGGTSQNTA
NIAADLQNKYGVDVIAHLTCVSSTKEYVDSMIDAYKEKRIENIMALRGDIPKEGRVCYDY
DHAYQLIYDIKSKYSDCCIGGACYPEGHVECARQSEDIVHLKEKVDAGCDFLTTQMFFDN
STLYQFLYRIREKGIDVPVLPGIMPITNVKQVSRSVALSGSTIPQKMKIMVDRFADDPDK
LREAGIIYASDQIIDLISNGVSHIHVYSMNKPEIAAGIMRNLATIIK
>A0A1T4VXK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium uniforme|TrEMBL
MQISKLFDGDKTVLSYEIFPPKRNDSIDKIYDTIEKLSDLNPDFISVTYGACGNIADSKT
ADIAQLIKDKYNIESVAHLTCINTGKEELDYILNDLESKGIENILALRGDINPDIKPKKE
FKYASELATYIIKRGGFYVSGACYPEVHVEAEDSIADIKNLKKKVDCGVSHLISQLFFDN
EVFYAFKDRARAADINVPIEAGIMPVTNKKQIERMVTLCGASLPAKFVKVLQKYEDKPEA
LVDAGIAYAVNQIVDLVANGVDGIHLYTMNNPYVARKITESVKNIL
>A0A380DLZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPGIKMSDEILQ
QFEAVKDDKVKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAAYSKSITAHK
EAIL
>A0A0M0BQD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|miscellaneous Crenarchaeota group archaeon SMTZ1-55|TrEMBL
MKELQTNKFVFTGELEPVKTADLSDVIQEAQALKGYVTACNVTDNPGSCASISSLVASHV
VQKTTGMEVVYQLRCTDRNRIALTSDLLGAAALGIRNVLALTGDHTLLGDMPNAKPVFDL
DSTVLVGMIRRMVDEGKDLNGNEILGSRPRFNIGVAANPNANPIEPEILKLVRKIECGAQ
FIQTQVCYDIDKTIEFLRMFKVFKTPVLVGIFPMKNYGTADFFNAHIAGVSVPKNLMEQF
AEVKKGGYSKQEKREKYDQINLDFFVPFVKELMKSNLCKGCHIMSVHYTELIPKLLKEVQ
VLPEPAVSVVST
>A0A6I4R5C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. L-22-4S-12|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVGVPTAPHLSCVGDSKDELRSLLSQYKNSGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGDHFHIEVAAYPEVHPQARSFEDDLQNFVRKCRAGADSAITQYFFSADCYFY
FVERVRKLGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDLESIQAFG
EQVVSEMCERLLAGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A349H315|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MQNLIEKMRETPVVFDGAMGTVIYSRGVFINRCFDEVSLTAPDLIRSIHEEYLRAGADVI
ETNTFGANRIWLQGYGLAEKTVEINLAGARLAREAAGASAYVAGSVGPCLRAGQILSAEH
SDRLADAFRECTEALARGGVDALILETFTNIDELLLAAGVAARTGLPVIASFTLSMGDAA
QQERVVLDTLARLDQSPDVHAIGVNCGSGPAPLFQVLEKTINRTAKPVVVMPNAGQPQQV
EGRMLYLATPEYFTSYGKKFIEIGARGIGGCCGTTPEHIRDLAKAVHTLGGVKKYIEIKP
AVAPANAVAPIPMAAKSRFGGKLARGERVTSIEVLPPRSCDLSAMLQKVRQCYLAGIDAI
NIPDGPRASARVSPMIASIAIREKVGIEPILHYCCRDRNLIGMQSDLLGGYAAGLTNFLI
ITGDPPKIGDYPDVTGVFDVDAIGLARMVSNLNQGMDIGGHPINPPCGILIGVGINPCAL
DLKNEIERFRRKIDAGAEYAITQPVFDAEALFRFIDATSDFSRTVPIVAGIWPLVSFKNA
EFMKNEVPGVEVPDSVLERMRFCATREDGIRVGCEIAREIRDKISSAVAGFQVSAPFGNV
ELAINVLN
>A0A6N6PNY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MQFIRDIHSACRAASRPAVSFEFFPPKTDEGDRNLMDKTLPALLALKPDYCSVTYGAGGS
TRDKTIGIVDRIQREHGLTAMMHLTCVNSTRAQLGEVLAEARARGITNILALRGDPPGGT
GEWIATEGGFQYSSQLVQCIRELGGFSIGTAGFPEGHIAQTAGKLADWDFLAAKIEAGAD
FVITQLFFDNEDFYRFHDYLVKKAGRPLTIIPGLLPIVSGRQTKKFTEMCGSRLPAPFVA
RLDALGDDDAAVIEYGIEYCTRQCEELLKFGVPGLHFYSLNKPHSTTQVVRNLDLAR
>A0A1H7LHS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. OK003|TrEMBL
MKADLRSVMQERVLIGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
HETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGANGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLEEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGVPMSVYPNAGAADYVD
GQFRYGASPEYFGQTAVQFADLGARIIGGCCGTTPDHIAAIAQALVEYTPAPILEPDPSE
SKPRIILHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVSFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATEHFKGIYLMTPFMFY
SMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A7Y4QKB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHLIRDIYAAKKNERKPVISLEFFPPRTDDGDKALLEKHLPALMKTGPDFCSVTYGAGGS
TRDKTLMIVDRIQREHHLTALAHLTCVNHTQEQVGELLQKIKNIGCKNILALRGDPPTGG
EFTPTPGGFEFSSQLVKFIREQNGFSIGCAGFPEGHIACKEGKLVDWRRLKDKINEGADF
VITQMFFDNTDYFEFRDHLNKLGVNVPLVPGMISIVSATQIKKFTQLCGAKIPPALGAKL
DAIGADDAAAAEFGIEYCTRQCEELLKAGVPGLHFYTLNKAASTVRVLQNLKLA
>A0A8J1U956|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Owenia fusiformis|TrEMBL
MPEALLGLEDSEIKSKERCMFKSQMSRPSSPVLPTYKYTSLIDRIHKRAESGDPFFSLEF
FPPRTYNGAVNLIARFDRMSEGQPLFCDITWHPAGDPSSNKPTSSTMIAGTMLNYCGIDT
MLHMTCCNCTKEHITAFLQKAKDLGIRNILALRGDPPQDEDWAPTEGGCNYATDLVRHIK
QEFDDHFVICVAGYPTGHPDCTSYEDDLKYLKEKVDAGADFIITQLFFKAETFLSFVKDC
QAIGIKCPIIPGILPIQAYQSLRHIVKLSRLEVPQEILDAINPIKDNDEAIRNFGIDMAV
ELSKTCLDSGLVHGLHFYTLNREVATIEILKRLGMWCEEPRRSLPWKPTANHTRCTEDVR
PIFWRSRPKSYIHRTSNWDEFPNGRWGNSSSAAFGEITDYYLFYLKSKTPKEDLLKMWGQ
ELQTEQDVWDIFHKYITGEDNAQGTKVTSLPWNDDLLSPETGLIKDRLADINRRGALTIN
SQPNCNAVSSSDPALGWGNKNGYIFQKAYLEFFTPRENVDALKTVLQKYSDRVNYHIINN
NGEEDYSNCDSMEPIAVTWGVFPGREIIQPTVVDPIAFKHWKDEAFGLWQESWGHIYPDD
SVSRKTIDFIHDNYYLVNLVDNEFPLESCLWDVVDEMFIEAERSHKTLPVSSHGEGEPME
LGNTTSLSSS
>A0A6G2MEK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4923|TrEMBL
MALGTPSTRTDHARTVREMLATGATSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVKATQDIAAESTLTPVAHLTAVDHSIAELRNMVGQFADAGIRNILALR
GDPPGDPMGPWVEHPQGVKYAADLVRLIKEAGDFCVGVAAFPERHPRSDDWDTDIRHFVD
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCETPIIPEVMPVTSVRQLERFPQLSNATL
PDELKDAILAAKDDPAAVRSIGIDFATRFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A2A8FGI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS026049|TrEMBL
MNFRKELKERMLVGEGAMGTLLYSNGIDQCYEELNCTNPDQIESIHRAYLEAGADILQSN
TYGANFNKLKRYGLEEEVSRINRQGVILAKKAAKGKAYVFGTIGAQRSIRKSDLSMEEIK
RGFREQLYSLLMENPDGILLETFYDLEELETVLQIVKNETGLPIIANVSMHELGNLQNGI
HLNEAFQKLEQLGADVVGVNCRLGPHHMIRALEEVSLPKQASIAIYPNASLPDYVDGRLV
YKAVPEYFGSSALELREQGAAIIGGCCGTTPLHIQAVKHAIGSLAPVKEKFTKSREIEVI
EVNDRELELPLYEKAKTERTILVELDPPKKLGIESFMTGAEVLKKAGVDSITLADNSLAS
PRISNDALANLLKNQLNINPMVHITCRDRNLIGLQSHLMGLQTVGLNEILIITGDPSKIG
DFPGATSVYDLSSFDLISMVKQFNEGLSYSGQSLGQRANFKIAAAFNPNVKYLDKAVLRM
EKKIACGAQSFLTQPIYSVEQIEEVYEATKHLETPIFIGIMPLTSTRNAEFIHNEIPGIK
LPDNVRRAMALAGDDPVKSRIEGVNIARELVDAAREKFKGIYLITPFLRYEMTAELTKYI
RKVDSKQTSEVAVHE
>A0A8E1ZX59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macellibacteroides fermentans|TrEMBL
MKVIDLIQGSGKTAFSFEILPPLKGNSIQKVYNVIDKLREFDPKYINITSHHSEYIYKTL
PDGKMEKVNIRKRPGSVAIASAIQNKYNITAVPHIICKGFTKEETEYALIDLNFLGVYDL
LLLRGDIKTLEAADANSKLYHNHATDLQEQINNFNKGIAVDGSTFEANETPFSYGMACYP
EKHEEAPNMDSDIHYLKQKVANGADYLVTQMFFDNQKYYDFVERCRAEGIQVPIIPGIKP
VVFKNQLTVLPKIFRSDIPEPFASELRKCNTDEEAREVGVEWCINQCKDLVAHGVPSLHF
YTMMATDSVYRVAKEIY
>A0A2A5YKQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium MED-G04|TrEMBL
MTDLKDAIAAAGQHWSIEVTPPGATKIDSFAEILAPDTTVNVTFLPGTDPMDTVDVAVRL
RDDGMNPVPHIAARSVQSRDQLGSIVKEMASRANVDEVLVIGGGVDNPVGDFASSMEILE
TGVLQENGISRIGVSGHPEGSPDINDDQLAEALEWKNDFARREGLELYIETQFCFEADPV
IAWENRIRARGNDLPIRIGIPGPATIKTLLRFAQISGIGPSMRMITKQARNVTRLLTVQS
PHTLITGLAEAMANDPESRLSHFHYYPFGGFARTEKWATAVAAGDFDLLPKGGFSVKEN
>A0A5W2ADG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Pretoria|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2V6GAT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIIRGDFPTFSFEFFPPKTPAAAEVLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIRHTTKLDPIPHLTCICHNEDEVEAILLRYARSAIGNILALGGDRPRDVPYDRSR
DSFQHAVDLVKFIHRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHFKAKVDAGA
DYIVTQLFFDNRDFFDFRERCALAGIHIPIIAGIMPVTSMSGFKRIAELAGGARFPARLL
RALQRCENDPEGVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRVIFDSLGIQPRR
SAQAPTVQPGDEVRKRVAN
>A0A2V6H6E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITEIMRGHSPTFSFEFFPPKTRHAAETLYQTIRDLESYMPDFVSVTYGAGGSTRKLTH
DLVERIQHTTKLDPIPHLTCVCHKEEEIDAILLRYAKSVIGNILALGGDRPAGMAYDKSR
DSFQHAIDLVKFVRLFNESGVHRDRRGFGIGVAGFPEGHPATPNRLVEMDHFKAKVDAGA
DYIVTQLFFDNRDFFDFRERCGLAGVHIPIIAGIMPITSITGLKRMAELAGGARFPAKLL
RALQPCQNDPDMVRHVGIQYALEQCHDLLTNDVAGIHFYTLNQSGATRMIFDSLGIPRNR
NLQASNV
>A0A1E5RMJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hanseniaspora opuntiae|TrEMBL
MKVDEKITQFQEKNSFEIPSFSYEYFVPKTLQGSYNLYERIDKMHKDSNPLFVDITWNAG
GIINPSSSQKKQEISKFSGKLIPKTPQTNDIIDTTQQALNLDSCMHMTCTNMTIKEIDTA
LKKAYNSGCQNILALRGDPPRETKSESESPDGNSTEKVKKYPFKYAIDLIKYIKEKYGDH
FCIGVAAYPEGHPEEKNADKLIDYLKQKVDLGATFIITQMFYNSDLFIEWCKKLRAAGIP
ESVHIIPGIMPITSYDSFLRRCNWCQIDVPAELNDILKPVSQDDEALRNLATNYLAKMCL
KLFRSGYVKHLHFYTMNLEKGSFVILRELERLLGKRLLPLTSGIISNPNKENEIQPIFWR
SRPFTYIERKKKSQKXXFKRQSSFNDPENKSVTPAPTSSASGSSSSXEFSDIENEDIDDV
NNEHNFDSELIDDEFPNGRFGDSSSPAFGNLDLSLTQLIRQSESKSLSVWGTPTSLKDLG
DLIINYLKGDLRSLPWCDTSVALEAKQLLRLLISLNQGGILTVNSQPKANGVPSSDPILG
WGPSLGYVYQKQYIEFLLPKRKLKDFLLLMNQKTTTTFTYLISDSQDEIFIYKGDDGQSR
VMASDVTKKADIEKSSVLQKYNDLLPDICKKMYCQCFHGCTKPTAVTWGCFPGREIVTST
IVEKNSFLMWRDELFAIIKEWKNNFVSISKNPVSIKKEKSAKGNAKNKHSESENEPAAKK
QXVSEDDLSEKSSKAAXVLDSVLDDYLLVSLVDNDYVSPGDLLLFTLLQLAD
>A0A2V5Z9B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
YALDQCHDLLDNDVAGIHFYTLNRSDATRVIFDSLGIPRHRGAEASSV
>A0A317MXM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plasticicumulans acidivorans|TrEMBL
MPAAIFIGHRSGDSESMDTQRRYPQVCSCEFFPPHSEDGLQKLLVTSAELDALRPAFRSV
TYGAGGSTRERTFVTVTALGGLGIDAAPHLTCVGSTRAGIAEILEEYRVQGVRRIVALRG
DVPSGMRDIGDFRYANELIEFIRASTGEHFHLEIAAYPEYHPQSSRPERDLDNFARKVQA
GANSAITQYFYNADAYFHFIDEIEARGVDIPVVPGIMPITNFTQLARFSDACGTEIPRWM
RRQLEAYGEDRDAIRAFGLDVVTALCERLLAAGAPGLHFYTMNQSGPTLEIASRLGLLQA
>A0A2V5VL27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
HHLVERIQHTTKLDPIPHVTCVCHNEKEIEDILVRYAKSAIGNILALGGDRPHDIPYDKS
RDSFQHAIDLVKFIRRFNESGAHPDPRGFGVGVAGFPEGHPATPNRLIEMDHFKAKVDAG
ADYIVTQLFFDNRDFFDFRERCALADIHVPIIAGIMPVTSMSGFRRIAELAGGSRFPAKL
LWALRRCENDPESVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRVIFDSLGIPRR
RNAQAPTV
>A0A410RWS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus coralloides|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTVEELAPLEPGFVSVTYGAGGSTRDRTV
DLVTHIKEKTGIEAMAHLTCVGHTRDELRDVLRRLDAAGIENVLLLRGDPPQGQTTFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVGALKGRS
>A0A1Q5LDC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02400|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVHAAGCETPVIPEVMPVTSVKMLERLPKLSNAVF
PEALEERILAAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A2V5YMJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRADSPTFSFEFFPPKTTEAAETLYKTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTQLDPIPHLTCVCHNEGEIERILLRYAKSAIGNILALGGDRPLGIAYDKSR
DSFQHAIDLVKFIRRFNESGTHPDRRGFGIGVAGFPEGHPATPNRLVEMDYFKAKVDAGA
DYIVTQLFFDNRDLLDFRERCALANIQIPIVAGIMPITSIGGFKRIAELAGGARFPAKLL
RALQRCQSDPEMVKRVGLHFAIEQCHDLLDNAVAGIHFYTLNRSDATRVIFDSLGIPRRR
NPEPSSV
>A0A3D1TJF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIQDVFAQHRTTTSFEFFPPRDPQAAENLLATIRQLEELKPSFVSVTYGAGGSTREMTH
QLVVRIKTETSLPAIPHLTCVCHTEEEIRGILVRYAEKGIDNILALGGDPPKDRMDWDRG
RDGFRYAGELVAFIQKFNASGLHPNPKGFGIGVAAYAEGHPATPNRLLEMDYLKAKVDAG
ADYICTQLFFNNADFYDFRDRCSLAGINIPIVAGIMPVLSEKGLKRMAELAAGMRYPAPL
LRAIARCNGDAEAVERVGIHWATEQCRDLLDHGVRGIHFYTLNKSDATRRIFSSLGLRDG
STL
>A0A0A2BVU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus sp. MIT 0602|TrEMBL
MNSILQKSLASSDITITAEVMPPRGGDISKTLAAAENLNGFVHSVNVTDGSRAIMRMSSL
AVCKLLLENNIEPILQIACRDKNRIGIQAEILGAHALGIRNLLCLTGDPVRAGDQPNARP
VHDYESVKLLKQVAAFNKGEDPVSGLLPNGPTELFPGAAADPNSTNANSLRKRLERKKLA
GARFVQTQMIMDARNLEQFCKEISDPLELPVLAGVFLLKSAKNAEFINKVVPGACIPTSI
VNRLANAKDPSLEGIQIAAEQVRRFTGIAKGVHIMAIKAEHHIPAILNQAKINLPSL
>A0A2U1AVF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter virosus|TrEMBL
MKVTEHFQNANGKTLFTFEILPPLKGENMKTLFNHIDPLMEFKPPFIDVTYHREEYIYKQ
RENGLLEKRSTRKRPGTVGICAAIQNHYKVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLVLRGDCVKSEQRFVPEPDGHTYATELIGQVVNMNKGCYLDDEQAYHNSTDFCIGVAGY
PEKHFEAPNITSDLRWLKKKIELGAEYIVTQMFFENQRYFDFVNRCRAEGINVPIIPGLK
PMTTKTQLTLLPSLFHVEIPCALADAIEACPDNKAAAQVGVEWAIQQSKELMEFGVPCLH
YYSMGKSESVRKVAEELF
>A0A5E4RTL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea iniqua|TrEMBL
MTQPSFSFEFFPPKTAEGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQGTIDTVVEIQR
EGVEAAPHLSCVGSTKDNIRDILQTYRSHGIRHIVALRGDLPSGMGEIGEFRYASELVEF
IRAETGDWFHIEVAAYPEYHPQAKSPRLDLEHFANKVKAGANAAITQYFFNADAYFRFVD
DAARLGVNVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTALCERLLADGAPGLHFYTLNAAAATKAMWQRLGL
>A0A2V5S5G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRRDSPTFSFEFFPPKTPEAAEILYQTIRDLESYMPHFISVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCICHSEEEIEAILLRYARSAIGNILALGGDRPRDIPYDKSR
DSFQHAVDLVKFIRRFNESGAHPDDRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYMVTQLFFDNRDFLDFRERCALAGIHIPIIAGIMPITSISGFKRIAELAGGARFPAKLV
RALQRCENDPEGVRRVGVHFALEQCHDLLDNDVAGIHFYTLNRSDATRVIFDSLGIPRRR
SARAPTA
>A0A7M2X7A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. ES2-1|TrEMBL
MAKASIIHPNWDKTPDGITDGFSLEMTAKDEASLRDAAPLIPAETPIAVTFLPGEDVGAR
VAATIAVRELGFEPMPHFSARRITSEDDFEGYLRAVVEKAGVTRCFIVAGDPPEPVGPYF
DTSALIATGAFERSGIKAIGIGGHPEGHPNMTEAECWAVLEKKVAEITARGMAPLIVTQF
GFDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVT
NLLGTAGPDKLVDAFARGLGSEHGKVRLHFYPFGGLTKTLEWIHGYNKKHGIGQGA
>A0A7W5C9E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus endophyticus|TrEMBL
MRISLELVPRDSEGLKAELQLIKTEFPAINTINIPDLTRFDLRSWEASRLSKSYYRDCIP
HIRAMDFDAGRPFDLIEYLDKHHISEVLIVTGDEPQNSTKQVYPTTCIDMVTKLKREHPH
LKIYSAIDPYRTSIRKEYEYVQQKLDAGVDGFFSQPFFDLRLMELYADILEGTDIFWGVS
PVVSETSKRYWEKRNHVVFPKNFEPTLDWNIAFSKEALAYTQETNSSLYFMPIKVDLQDY
FNGIFGEVLVKNA
>A0A5E4KTQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon|TrEMBL
MSFESKLDEGKFVVTAEISPPKGTDTSGLLKDASIINGFADAINITDNQRAVMRMSPVAA
CSILESKGYETIMHVTCRDRNRIALQSELLGAYALGIKNILVMSGDHPVKGDHQGAKPVY
DLDSVQLLGLIQKLNSGFDFSGNRLDGKTNFCIGAVTNIELNEIALMKLEKKISQGVRFI
QTQAVFDIEKFSGFLDRIKDSGISRSRIIAGIIPLKSEKNARFLNKNIAGIKVPEIVIDQ
LKNASNPETRGMEIAARLIKELHGMCGGVHIMPIGNHEKTKDILEMAGII
>A0A095ZDD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierellia bacterium S7-1-4|TrEMBL
MTKIQNIKFPLVFDGAMGTYYPDKSKRVMPECEMANLFDSEVIYEIHKEYVDAGAMAIKT
NTFQANTVSLGTDFSVVKNVIEAGLSLAKKAVKNTETLVFADIGPIPGHDENSIDEHKEI
IDIFLENGINDFLFETFSEIGTLKELAKYIKAKDENTFIITSFAVGADGLTRTGEVGEDL
LSEAAKSTDIDAIGFNCVSGPLRLREYIEKINLPEKIISIMPNGGYPTVIKNRTYYSANK
DYFSNATLQFLEYGVQIIGGCCGTRPEFIREITERISEYRYTKTRHEKKKHARLETPYTE
NLFRNKLEHGKKPIVVEFDPPKDLNMKRYMENVKALSNSGADGITIADCPVARVRVDASL
TAYKIKNEIGIEPIVHMTCRDRNVNASKALLLGLNLENILNIITITGDPVPTAEKDEVKS
VFQFNSTKFATLVSDMNEKVFTNKMNIGGALNLNANKFDLEIKRAQAKEKAGVNVFYTQP
VISRTAVENLKIARKELKSYIMGGVMPIVSYKNALFMNSEASGIRLDDDIIERYKGLERE
EASRLAVEITSDFMRKIEDYVDGYYIITPFSRVDIVGELIQLFKTR
>A0A5H6JYS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Nima|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A397Q359|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dichotomicrobium thermohalophilum|TrEMBL
MNYANNRPDGAADGPDVKVSFEFFPPKNAQMERTLWETIRRLEVFAPRFVSVTYGAGGTT
RNNTHTTVERVLRETALEPAAHLTCVCATREEIDEVVHAHKDIGVRHIVALRGDPPEGIG
EVYEPHPGGYESSVDLVRGIKNIGPFEVSVAAYPEKHPESPSVQADLDMLASKVDAGADR
AITQFFFDNADFFRYLDRVRARGIDIPITAGIMPIHNFKQVARFAGSCGARIPDWLAKRF
DGLEDDPETARLVAAGVAVEQITELLEAGINEFHFYTLNRAGLTAAICHSIGLKPQTPER
PAEPRTNAA
>A0A5N8YIC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium AC-409-J13_OGT_754m|TrEMBL
MAKVIETTMKSSTTPVIICDFSAPRGSDLRFLDDAQHLDVDFILIAYNPGKSVRMDPATV
AYLIKERIGKEVIVTLATRDSNRLSIQSNLLGVSGLGLENIMVVEGDPFSETELALVKGV
NDFKPTELIRSINVMNQGLDFKGLSFKSPTDFCVGATIDINRSVDKQVLLTSRKIQSGAE
FFVAQPTFDIRQVELFYDQYSRVNGRSISQPIFWGIQILVENGVTF
>A0A1T4PYP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichlorobacter thiogenes|TrEMBL
MKIADKLATGCHFISVEYFPPKERQDWPAFFKVVERLASLNPLFASVTYGAGGSNQDATL
EIVTHMQQQLGLETMAHMTCVGAQADRLNRFLDNLSKAGIQNILALRGDPPLETPVEQLT
ESPFHFASDLVSFVGQSHPEMGISVAAYPEVHPEAISADADLGYLKLKMDLGGAFAVTQL
FFDNQLYFDFVKRAQERGITKLIIPGILPVLNLKMIERIKQLSGAFIPPAFMAALEEADQ
RGGAAEVRKVGVAHARKQAEELLAAGVQGVHLYTFNKAEAILELTEGLLP
>A0A1M6TRK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermus profundi|TrEMBL
MKVIEILDQATGPLISYEIIPPRRGGSLDEVLAVVEELMPFDPPFIDVTSHAAELEYEQL
PDGTLKPRVKRKRPGTIGICAAIKSRFGIETVPHLLCRGFTREETEDALIELHYLGIQNV
MALRGDAPNYRKPIPPDRTVNEYAVDLVRQITNMNRGIYLEPLEDAVPTDFCIGVAGYPE
KHCEAPNLTWDIMHLKRKVEAGAHYITTQMFFDNRHYFRFVERCREVGIEVPIIPGLKIL
TSKRHLQLLPSRFHVEIPEALASEVEAARPEHVPEIGIAWARRQAEELLEAGVPCIHFYI
MLRADYVRQVVAYLRKMA
>A0A067BH30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio metoecus|TrEMBL
MGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWNSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWNNGIQNIVALRGDI
PAGGGKPDMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPNWMVKQFEG
LDEDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRPQV
>A0A4S4AT73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azoarcus nasutitermitis|TrEMBL
MHKTELSIEFFPPQTAEGADKLRAVHAKLAELKPAFFSVTYGAGGSTRERTFATVRAIAA
AGSEAAPHLSCIGSTREGIREILREYADAGIRRIVALRGDLPSGVGDPGEFRYANELVEF
IRAETGSRFHLEVAAYPEWHPQARTPADDLAAFKRKMDAGADSAITQYFYNLDAYLHFVD
AVRRLGIDKPVVPGIMPIASFSKLARFSDACGAELPRWMRRKFEAYGDDAESIRAFGLDV
VTTLCERLIAAGAPGLHFYSMNQAGLTSEICRRLKLG
>A0A3M2XIY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. maculicola|TrEMBL
MVXXXXXXXXXXXXXXXXGMASGELRHANDLVAFIREETGSHFHIEVAAYPEMHPQARNF
EDDLKHFVTKANAGADSAITQYFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLAR
FSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEDVITQMCERLLEGGAPGLHFYTLNQAEP
SLAVWNNLQLPR
>V4AQ46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lottia gigantea|TrEMBL
MPEVALRDTDVKHKNGSAIKIQGDVSPSESSRSSSPKSISPCSDRGSTRYRCKPKYSRLI
DRINQRKLSGDSWFSLEFFPPRTNNGALNLIQRFERMARGKPLFCDITWHPAGDPGNVDT
PTSSTCISGTMVNYCGIETMLHMTCCGQSVETIKDHLQKAKDLGIRNILALRGDPLVDDG
DWKYVEGGLNYATDLVKLIKEEHGDYFVICVAGYPTGHPECTSYEDDLKYLKEKVDAGAD
FIITQLFFEAETYLKFLQDCRDIGITCPIVPGILPIQAYQSLRHIVKLSKLEVPQEIIDA
INPIKENDAAIRNFGIDLCVDLCKHVLASGDVGGLHFYTLNREVATIEILKRLGMWTEEV
RRPLPWKLTANHARCKEEIRPIFWAGRPNSYVYRTSNWDEFPNGRWGNSSAASFGDLKRY
HLFYLKSNSAKESLLEMWGSELRREEDVWDVFYRYITGKKNEAGLQVTEIPWNDDEMSAE
TAIIADQLAEINKQGVLTINSQPAINAAPSNDPSVGWGNPNGYIFQKAYLEFFTSPENVE
ALKEILTDYPLVNYHILNHSGDADYTNCDESEPIAVTWGVFPGREIIQPTVVDPIAFKSW
KDEAFALWMETWGKLYPADSPSREIIHSIQKRYYLVNLVDNEFPKPSCLWEIVNKMLSRA
NVNLSDYDSVDE
>A0A2U9NH82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. R2A2|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDAKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A268TEF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. 11S03491-1|TrEMBL
MIEECVHKILNTKFLSYEITPPRGTNIGEELIKELQEWDGYDALVCTDAPLAKFKQSSIL
TSLKLQNTLKKPVICTLNMRDRNSIAIQGDILGANQLDVRLFLALSGDPVKLGDYPNAKG
VFEGNSTLLIHLINQCNQNKDLNDKPFKGEVKTIYPFGVINSYANNPLSLKNKMKRKIKS
GVLALFTQPIYDIENAKILVQWCAEINRELHTNTQLVLGYFPIMKYKTAQFLYSKLPGVF
VPQIWLKKLEEASLISQEQEQKVGFELSKKLFEDLKNTHYKIHFMNANKITLAKKILR
>A0A7V7KCB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSNVISGRLEHPKLAVALPLPSGVKVSFEFFPPKNEKMERNLWASMERLGTLDPTFVSVT
YGAGGSTRQRTHHTVVRILKETGLKPAAHLTCVGATREDVDDIAGRYWDEGIRHIVALRG
DPPDGGGAYRPHPGGYAYASDLVAGLKRIADFEISVAAFPETHPEAKSPEADLDNLKRKI
DAGASRAISQYFFDPEVFFRFLDKVRAAGIDVPIVPGILPVSNFRQVKKFSEACGTNVPD
WLGDLFAGLDDDAETRRLVAASIAAEQCRVLHAGGVGDFHFYTLNRADLTFAICHILGVR
PAAAGKEAR
>A0A7J7P260|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingdonia uniflora|TrEMBL
MIIKCICVLLGHLWIVDDNVALDKPLDFAALSSSRSSSVIHNNLFVFLCSLGEKDLGIIF
ELQDNLQVSEERTVRRCLEVSTRTPYECISIPKDKLWGKMEDLHREIEIMKLLSEHPNTA
RIKGAYEDQRVVYIVKELCARGDFFNLFVEKEYYSEKRQPYLLRQLSKWLNIAILWGVTH
RDINPDSFLFSNVDQEAPLKATSFRFFTFYKPKAHSDKLQSNGLADLDDYKSDLVYLKRK
VDAGTDVIISQLFFDTDIFLKFVKDCREEGISCPIVPDILPITTYRGYLRMIGICKTWVH
NFIPAYPLSAMSSQNLLVDIVNYSWFDSLCSL
>A0A0C4UTD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria rulei|TrEMBL
AYGIHLGTEMCKKILAHGIKTVHLYTLNLEKSALAILANLGLIDMTKIKRPLPWRPPANV
>A0A0Q4N0G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Leaf58|TrEMBL
MSLLKTALREQTFVCVMEFVPKPSAERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFNKPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DASKHQEAMHWMSRQATPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAEAAQSK
AFAQTRSVDRLALQIIGVKLMGYAGVHLSGVHQLKQLLALEARIEHWQEQIHSLEQWAPA
WHASWQMPGLPAVSFHPPQAGWRLGESRVDASLKEKARYHLMHGMHALVFSRRNGLSKAF
GWAVRQPLWATRLGAQVLHKVERAVKQPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVQQTAVLSERLIPCIEVQTRHRSSWPQWFAPQTP
RRLSPQPAPRTQPE
>A0A0Q4NUI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Leaf58|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEVDLGNFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A661X0Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MKVIEHLSRAKETLISFEIIPPKRGGDIHSLLKVVDDIARYNPPFIDITSHAAEVSYEET
PQGIKRKIKRKRPGTLGICALIQNKYNIDAVPHVLCHGFTREETEDFLIDLQYLGIENVL
AIRGENSGYQKPIIAGRSVNHYAVDLVKQINDMNAGKYLEEDLVDARPSNFCIGVASYPE
KHIAAPNLEFDIRNLKNKINAGADYAVTQMFYDNRFYFDFVEKCRQAGIDIPIIPGLKII
TSKRQLTSIPSAFHISLPTELTDRILEAKNDAEVLEIGIDWAYHQVQELLEHKIPAIHFY
IMQNSSPIKHLMEKLGL
>A0A2Z4UK17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MSSLGDRFRGRDDVRVSFEFSPPKTAEAEEKLWTAIERLAPLRPAFVSVTYGAGGSTRER
THSTVKRMVNETDLKPAAHLTCVGASKAEVDGVIQGYWDAGVRHIVAIRGDMPDMQGPYK
AHDDGYLSTADLVGGIKAIGDFEVTVSIYPERHPESASFDHDIELLKAKIDQGATRAIAQ
FAFETEHYERLLERVRKAGIDIPIIPGIMPTTNFKGVVRMAERCGATIPSWLAAYYDGLD
DELPTRRLIAATVAAEQVHDLERLGFRDFHLYTLNQADLTYAICHILGYKPHAVS
>A0A4P9DTU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caminibacter mediatlanticus TB-2|TrEMBL
MIDINKDRLITLETTPPKLPTIEPMIEKIKKSEAYKYIDGFSTTDCPLSKLKYNSIIAAY
KLQKNFKKPVIATITMRDRNKIALQSDLLGANDLDVTNILAITGDPASMSDQPNTKAVVE
GNSTLLLDIIRAFNNGMDYSGKEFKIKPKPITPFAVSNSFAKNFSSIEKKMYKKVKHYAK
GIITQPVFDEDIANKLISIRDKIRFEFKDTREFDLIFGFFPITKLKTAQFLKSHVPGIYV
PDEWIEKLIKAHKISEDEEYKVGLDLSKTLFEKLQKIHPKIHIMTANRFEIVKELF
>A0A2L1S8T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp. I507|TrEMBL
MIDDNLRASRKTADQRPDLQLSFEFFPPKTDAMEERFWDSIAKLAPLSPRFVSVTYGAGG
STRERTLRMVRRITTDTGVPAAAHLTCVGATRDEVDEVVRGYAEAGVNKIVALRGDPPEG
VGQPFTPHPDGYQNAADLVAGIRRLGNFDISVAAYPEKHPQSADWDADIDNLKRKIDAGA
DRAITQMFFSNTDFLRYLDRARKAGITAPIVPGIQPIHSFKQIAGFAARCGASIPDWLAE
RFEGLDDDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRT
>A0A3B8XTY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MSKTPKKERNERTSVSFEFFPPKTPEMEETLWKSIRRLEPLQPEFVSVTYGAGGSTRERT
HATVKRIHDETSLEPVAHLTCVGASKAEVDDVIRAYWDAGIRHIVALRGDMPELGAPYKP
HPEGYQSTPELIEGIRKIADFDVIVSAYPEKHPESESLEADIELLKRKVEAGATRAITQF
VFDTDKHIRFLEQARKAGVEVPIVPGIMPTTNFKGTKRMAGRCGASIPKWLDDYYIGLDD
DLPTRKLIAAYVAAEQVNRLRSYGFDRFHFYTLNQADLTFAICHVLGLRPQSVPATPETV
>A0A2E6QAF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSIPSVSFEFFPPATEKMADNLWRAVERLAPLAPNFVSVTYGAGGSTRDRTHATVKRLKE
ETALEPAAHLTCVDATREEVDEVIQSYWDTGIRHIVALRGDPPEDAERYNPYPGGYENAA
ALTSGIRGIGDFHISVAAYPETHPDSPSADADIDMLKRKIDAGAEQAITQFFFEPEYFFR
YRDAVTAAGLSIPIIPGIIPVLNLARIVSFAEKCGTTIPEWLRARFAGLEEDAAARKAVA
AEVATELCQNLRSGGVDQFHFYTLNQAELTYAICRNLGLKPSMDSETGQ
>A0A522A3S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MLWVGRLGHRLYEECGHHKLPAVQHVTAVFCSASVLVSRCLVTTAFSTSSVPLSAVTAPP
PITVSFEFFPPRTEKMHEQLWAAIERLAPLGPAFMSVTYGAGGSTRERTHDTVVRIQNEK
HIQAAAHLTCVGATRAEIDAVARRYWEAGIRHVVALRGDPPEGEAVYRPHPNGYAFASDL
VAGLKRVADFEISVAGYPDVHPEALSAAADLDNLKRKIDAGASRVITNLFMDTDVFRRYR
DRAAAAGVKVPIVPGLMPVTNFANISKFAQKNGVSVPRWLGELFVGLDEDPETRKLIAAT
VAAQQVQTLVKDGVSLFHFYTMNRADLTFAICHLLGLRANGHTPAAPGQG
>A0A2E4I527|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTSSSXSSILFDXPQDKERELGELLAAKVFVITAETSPPVSSDGDALLRRVEPLLGKADA
VNITDGAGARSHMASLAASALLVRAGFQPILQMTVRDRNRLALQNDLLGAGALGVKNILC
LTGDDXASGDQPEAKMVMDLDSRSLMKVARDMRDKGVLPSGRAVGEAPKFLIGAADAPGD
PKGGWSPDPIRAKIKAGASFFQTQFCFDIDLVKRYVSRLESEGLLEEASFLIGTGPIXSA
KSALWMNENLFGVNIPERIISRIQSSSDQRAEGKKICIELIEQLKLIKGVAGAHLMGPNS
EQAVAEVVQNSGVLSSRAEA
>A0A2E6GM03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSNNEKKFSQELPFPAGAPRDLKISFEFFPPKTEKMAETLWSSIQRLEPLQPRFVSVTYG
AGGSTRERTHATVVRILKETSLTPAAHLTCVNATKEEVDAVAQDYWQAGVRNIVALRGDP
PDGETAYQPHPGGYDYAVDLVEGLKRIADFDISVAAYPEGHPQASTIDSDIENLKRKIDA
GADRAITQYFFGAEPFLRFMDRVRNAGIEAPIVPGILPVQNFSQVVKFSDMSGTSVPAWM
AELFEGLDDDPETRKLVAATAAAEQCRQLHVHGITEFHFYTLNRADLTYAIAHILGLRPE
NITGDGEDSVE
>A0A3Q9AKZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1D.F.Ca.ET.043.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAPRHQVDAVIREFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A416VRC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odoribacter sp. AF15-53|TrEMBL
MKVIDILNNTDKAVFSFELVPPLKGGDINKIYEAIEPLIALAPPFVNITFHRDEVEYRQN
PDGTIRKVTVTKRPGSVALAAAIMRRYNVDMVPHIVCGGATRHKIENELIDLNFLDIENV
MALRGDPIPGERFFTPDEDGHRYSYELVEQIARMNHGQYLDDTLTDAVPTNFCIGVAGYP
EKHYEAPNQACDIENLKKKVDAGANYIVTQMFFDNSKFFQFVEKCRAQGITVPIVPGLKP
ISTFKHLEMLPRTFSIDIPQELVKEIRRCKNNKEINQVGIEWCVAQSKELIAHGVPAVHY
YTMGKSENIQEIVKQVF
>A0A2D6T139|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MNLLANRLPQAQLQPAAQLQAQSGMPAGISVSFEFFPPKSEKMEEALWRAIRRLEPLAPR
FVSVTYGAGGTTRERTHATVRRLVEETSLEPAAHLTCVGASRADVDAVAESYWQAGVRHL
VALRGDPPEGEAHYRPHPQGYAYAVDLVAGLKAVADFEISVAAYPESHPEAPSADFDLDN
LKAKLDAGASCAISQFFFDPEVFLRFRDRVRAAGITVPLVPGILPVTNFGQVVRFAATCG
ASVPDWLAESFAGLEDDPETRRLIAAMVAGDQCRRLAAEGVEEFHFYTLNRPELTYAICH
GLGLRPTSLCLAAEQS
>A0A439D9R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylaria grammica|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTGMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
STKSLELAEICQRELNLTTCLHLTCTNMSRKMIDNAAEYQDANEDPENAIDEGFVWAIDL
VKYVKNKYGDYFCIGVAAYPEGHADESHPLGQSLEHDIPYLVEKTLAGADFLMTQLFFDT
DAYETFERKLREHPSGAFKSIPIIPGLMPIQSYQMIKRTTKLSHARIPDEIMARLDAVKK
DDEKVKNVGVDILCEIVERVKEIQGRIPGPRGFHFYTLNLEKAVSFIVERVNLISSTPDE
EAVVDDGPLPNIPALVINGTSSLDHHAQDISQSRRQSTVGSEPRNRVIVSERTLSHPEYE
ASQADAGLKAGAINTRANTLAISEGEGVLGREATWDDYPNGRWGDARSPAYGEIDGYGPT
LHVTRAQAISLWGHPKSLEDVNTLFLGGPDVFGWGPRHGFIFQKAFVEFFISAAEWRTLR
EKLTSPEVRDTVTYYAANAAGDFVSSDLSGAAPPSGATEATDASNNGYSVGESSTNAVTW
GVFPGKEILTPTIIEEVSFRAWSEEAFGIFSEWAQVYGKGHESEKLLEAARADSWIVNII
HHDYMDKEALWDLLLK
>A0A3D5UTF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MSHTRSHSFSFEFFPTKTDAGHEKLLATARCLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVSTAPHLSCVGGSKQELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKMGVETPIVPGIMPTTNFKGTKRMAARCGASIPKWLDDYYIGLDDDLPTRKL
IGAYVAAEQVNRLRSYGFDRFHFYTLNQADLTFAICHVLGLRPQTVPAEPEAV
>A0A4R4RIM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. KC345|TrEMBL
MRRLRPNRPPTVRDLLASGGRSFSFEFFPPKTEKGARNLWRTIRELESLHPTFVSVTYGA
GGGTRDKTIDIVERIATDTTLTPVAHFTAVDHSQAELRNLIGRFAGVGVRNILAVRGDPP
GDPMGEWVKHPDGVEFASDLVRMIRSYGDFSVGVAAFPYKHPRSPDIESDTRYFIEKCRA
GADYAITQMFFRAEDYFRLRDRVEAAGCDVPILPGIMPVTQMSTIERSEQLSGAPFPPEV
RARFEAVADDPEAVRRLGIEHAARLCQDLLDQDAPGIHFITFNKSTATREVYGLLDGAYA
ASGSAPPITA
>A0A2D6G2X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MADMRTHDAAPGGALPVAAAPARGATASFEFFPPKDEAAGKALWACVERLAPLAPAFMSV
TYGAGGSTRERTHAVVARIQKDTGIAAAAHLTCVGAGRGEIDDVARRYWDAGIRHIVALR
GDPPEGEDRYTPHPGGYAYAADLVQGLMRIGDFEVSVAAYPEVHPEADSAAADLDNLKRK
FDAGAKRAITQFFFAAETYLRFRDTAAAAGIGAPIVPGILPVTNFKQVLRFAGMCGASVP
GWMVELFDGLDDDLETRKLIAATVAAEQCRALLVEGVTEFHFYTLNRADLVYAICHILGI
RAGHGPTDGTGKN
>A0A385HPG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus ruber|TrEMBL
MTFDSDSGPVGGGESRTPSVVDRLRAPRGARIPFSVEFSPPRDADAEARLWRAVREFERL
GPAFVSMTYGAGGSTRDRTVRVTGQLAQETTLLPVAHLTAVGHSIDELRAMVGAYADRGI
TNILALRGDPPGNPLGEWTRHPQGLEYAEELVRLVRDLGDFHVGVASFPEAHHRSPDLEH
DTRYLVHKLRAGAEYSITQMFFDVEDYLRLRDRVVAYDPEQGAKPIIPEIMPITSLRTAR
RSLELSGSKLPATLEERLVRAAGNGPEEDRAAVREVGIDVATEMAERLIAEGAPCLHFIT
LNFARATREVLARLGIAVPTAV
>A0A1H6LDC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bathymodiolus azoricus thioautotrophic gill symbiont|TrEMBL
MTFGALGTTQEATLETVLDIQKNDTVVAAPHLSCIGSKKEIIIELLDQYKAVNINRLVAL
RGDIPSGVRDIGDFHYANELVEFVKSQYNNHFHIEVAAYPEVHPESKNRQTDLQHFADKV
KAGADGAITQYFYDAEAYFKFVDEIEKLGVSIPIIPGIMPITNYTQLVRFSNMCGAKIPN
WILKKLELYQDDLDSLSTFGLEVVTNLCQTLKEQGVNNFHFYSMNRSQPSLEIAKHL
>A0A2D7TQH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MTSISFEFFPPKSAEAEEKLWRAIGRLEPLAPEFVSVTYGAGGSTRDRTHACVRRLVDET
RLRPAAHLTCVAASRAEVNSVVEAYAEAGVRHIVALRGDMPDMGGFAPHDDGYAGSVELV
QAISARGGFDITVSAYPEKHPESRSFADDIDLLKAKVDAGATRAITQFVFDTPAHLRFRD
AVAAAGVSIPIIPGIMPTTNFAGARRMAEACGTSVPDWLSAAYEGLEDDLDTRKHIAASV
ATDQCRMLIDEGFEYLHFYTLNQADLTFAVCRILGLGGGGQESDAI
>A0A6N7XXM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierella pigra|TrEMBL
MKIKQLFKDKKLVFSFEIFPPKPDYPVETIYDTIEELSVLNPDYISVTYGAGGSVNNNRT
CQLSHFIKSRYGIESLAHLTCIGSSKEYIDSIIRELRDKDIYNILALRGDIGNIGIGEFN
NSQELIQYIKESGNLGIAAACYPEGHIESKKDVDKDIRVLKLKEEAGADYFISQLFFDNS
YFYDFLDKAKQKGIKGPIQAGVMPVINKKQIERVVSLCGAKLPNKFLRIMNKYEYDKLAL
RDAGIAFALEQIVDLASFGVDGIHLYTMNNPYIAKNISKNIEFILSSINRKSVI
>A0A1M7Y5J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila aestuarii DSM 18488|TrEMBL
MIHNFNDDISTPEKFVVTLELIPGRDFSGDAIDTIKQISQDAYNDGRITAVSITDNPGGN
AALSPDAIGREILDFGLDVIVHFTCRDTNRMGMESRALQLARMGMKNILALTGDYSGKGF
GGRGTPVFDFDSVILTSMLNDLNKRLIKTGHSEVFVTGCAVSPFKYTEAESWVQYRKLQR
KIEAGASFTITQLGYDIDKYEELLIFNHENNIKIPALASLYLLGKGAANIMQQGKVPGVY
VSKRLYETIAKEYEVKGEGPKKAIERLARLGVVLKGIGYKGIHIGGVHKSFDTVAAILDR
MDEIQHNWQDYREEFQEEQNGRFYLYKQSAEQKNGMSKQDDIKLKYTDGAHYLFLRTAHD
LFFDKRASLAPVYKKISATLDKSNSSWMLKAFLEDPFKKLMLSCQSCGDCGIQHVGFLCP
ESGCPKHTRNGACGGSRDGYCEVHEDKFCVWVRAYYRMKRHNETDRLTATFVPPRLWELK
DTSSWINFHLDRDHQREDKAA
>A0A7H8VEU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter indicus|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDKDIQHFVEKVNAGANAALTQFFFNPDAYFYFV
ERIRQAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVLKFCERLIAGGAPSLHFYTMNNTEPTRQLVTDLGLA
>A0A7K3QR36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces bauhiniae|TrEMBL
MERVLGVSGRAGTLLDGVSLEMTGKDVPRLTEARAALDGGTRINVTYLAGEDTGMRLAAA
RAVREHGFVPVPHLSARRLPSSAELERFLAGLAEAGAAENVFVVGGDPARPEGPYEDALS
VIRGGLLQRYGVRHVGICGYPEGHPAIGDDALWSALTGKAAALEEAGLAGDVITQFGFDA
DAVLTWLQALRGRGVHLPVRVGVPGPAGVRRLLGYATRFGVGTGATVARKYGLSLTNLVG
TAGPDRFLDDLAGGYDPACHGAVKLHFYTFGGLRTTAEWITRYRRERG
>A0A7V9W3X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas kenyensis|TrEMBL
MSTSYPLGISFEFFPPNTEVGREKLVGVRDALAERNPRFFSVTYGAGGSTQGRTLDTVRA
VREAGITTAPHLSCIGSEKAQLRDLLVQYREEGIDSLVALRGDLPSGMGGIGELRYANEL
VEFIREETGDHFEIAVAAYPESHPQAPSFERDLENFVRKMKAGADLAITQYFFTAEAYFH
FVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAEFG
TEVVSRLCQRLLDGGAPGLHFYTLNQATPCLRILDNLA
>A0A1R0X153|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus odorifer|TrEMBL
MKPDLRSAWGNKVLVGDGAMGTYLYQKGFPVGISYEELNLTSPGVIEDVHRSYIEAGAVL
LESNTFSANYDRLSKYGLESKVEEINRAGVRIARQAAGDHGYVLGAVGSIRAGKRANLSS
TELKKYFTQQIAALLEEDVDGIMLETFYDVEELHLALRTLRKISSLPVVCQLAVDETART
LDGLTLPEAFRILEGDGADVIGFNCNTGPNGMKRALKAVQGNLVLPASVYPNAGVADYVD
GEYRYGASPEYFGQMAQTFAEMGCRIIGGCCGTTPQHIAEISSALKNYVPQPLPKPLPPA
VERVSLQEDFGDEDRDGREPNLVDLVKERHTVIVELDPPRELDIAKFMQGAEVLRRAGAD
ALTLADNSLAVTRMSNMALGHLVHAKTGLRPLVHIACRDRNLIGTQSHLMGFDALGIDHV
LAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGISFSGKPLKQKANFVIGAAFNPN
VKHLDKAVQRLEKKIASGADYIMTQPVYDQELIVKIAEATAHLEIPVFIGVMPLASGRNA
EFLHNEVPGIQLTDDVRNRMKGLEGEAGRAEGVAIAKELLDVATAHFNGIYLMTPFMFYD
MSAQLMEYVWEKSGRKLSPLFR
>A0A1E3H168|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobrevis pamukkalensis|TrEMBL
MIADYWAAGVRHIVALRGDPASGVGDRYQPHAGGYASTPELIAGIKAIGDFEVTVSAYPE
KHPESPDLVADIQLLKRKVEAGATRAISQFFFDNDVFERYVEKVRAAGIDIPIVPGLVPV
VNFTQTAQFARKAGASVPAWVVKRFEGLEDDPETRKLVAATVAAEQALDLVGRGFRDFHF
YTMNRADLVYAICHLLGLRAQPQAARSVAAA
>A0A1E5G348|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuribacillus alkaliarsenatis|TrEMBL
MLIRDKFREKKPLISFEIFPPKKEYPVDTIYETIDDLYNMVPDFISVTYGAGGSTKGTTV
DIASYITEKYGLSALAHLTCLTSSKEEITEILQALNSKGVRNILALRGDYPQKVDSNAEF
PCAYSSALDLIKHIKQEGDFCVGAACYPEGHPDAKSEHEEFTYLKDKVDAGADFLVTQLF
FDNEIFYRFMEQAQKYNINVPVVAGILPVLNKNQVEKIVSLTGCAMPKKFLRILDRYEHN
PEALREAGLAYAIEQMIDLMSWGIDGIHIYTMNKPDATREIVNRIIEVRGALAGKPS
>A0A1R0ZQB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus odorifer|TrEMBL
MTPPKASHSPEKISEIAQKQVERLKNVDLDALILYDVQEEAERVDHERPYPYLPTIDPAI
YGDKYLRQVEVPKIIYRCVGNDTRASFADWIKTDESEDRFSVYVGASSSKQEVKLNLPDA
YKLSKQLNSNLNFGGVVIPERHIKKNDEHIRVVEKINNGCNFFITQATYNVEASKNLLSD
LYYYYTNKGFEMVPILFNLAPCGTAKTLQFMKWLGISIPGWLENELKYSNDILDKSIQLS
QKIFEELFEFGLEKGIPIGCSIESVSTTKLEIEASIQLAKDVKAFLDKKLLSLESR
>K5ZSW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides merdae CL03T12C32|TrEMBL
MKVIDLINSSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSFQKINIRKRPGSVAIASAIQNKYGITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQKTDIYHEHATDLQQQVNDFNKGIAIDGSAFEANETPFSYGMACYPE
KHEEAPNMDSDIFYLKEKVKNGADYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDDEAKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVYKVAKEVY
>A0A4Q4KR88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brumimicrobium glaciale|TrEMBL
MKVIDHINEAKDTLFSFEILPPLKGKSIQSIYNGIDPLMEFKPKFINVTYHREEYVYKER
DKGLLEKVSIRKRPGTVGICAAIMNKYHVDAVPHLICGGFSKEDTENALIDLQFLGIDNV
LALRGDPIKTEVTFKAANKGHKYAVELIEQIQSMNRGQYTMDEIQLEPTDFCVGAAGYPE
KHFEAMNMATDLQYLKQKVDMGADYIVTQLFYDNSKYFEFVKKCREIGITVPIIPGLKPI
SNLRHISFLPKFFNIDLPLELSTELLKCKTNEDVKQVGIEWGIQQSKELKAAGVPCIHYY
TMTNSTEVRKIASELF
>A0A4Q1JZ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas composti|TrEMBL
MTSISFEFYPPKTDEQRAQLDRAADKLKKYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASELISFI
RAEHGDAFHLEVGAYPETHPQASDALSDLKHFKAKVDAGANAAITQYFYNPDAYFGFVDA
VRKLGVEIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIAKRMTAYGDDAAAIRDFGADVV
AQLCQRLIEGGAPSLHFYTLNLAKPTQLVLSRLG
>A0A2M7JSW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_8_14_3_um_filter_45_9|TrEMBL
MSFKEQLESGKFVVVAELQPPKGNDLSELYEYTELLKGRVDAINIPDLQNAIMRLGSLSV
CTLLKARGMEVIYNLSCSDRNRLALQSELLNASALGLKNVLLLQGDHPSIGDHFEAQAVF
DLDVMGLLGTAKRLQEGYDLMGNDLQGKPQFCVGAQINATAKGHVLDLEIMDMEKKIRTG
VDFFFTNSIYDVSLFEPFVKKVAHFKVPIIVAITLLKSVGMARYVNKHVEGASIPDSIID
QLMKASDKQKVSNEIAGGLIKAFKPLCQGVQLIPIGWEKQIPTLLDDVGL
>A0A2P1RZY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium ulcerans|TrEMBL
MKISELFKNKKTVVSFEVFPPNTIYSLEDVYSSIDELAKLQPDFMSVTYGAGGATRGRTV
EIASKIKNDNKIEALAHLTCLGAKANEIDDILEQLRKNNIENILALRGDKPKDGLPVEEG
DFKYAQDLISYVKGRKDFSIGGAYYPEGHQETNDLLDLFNLKTKVDSGTDFLISQIFFDN
ESFYRFRDKVDKLQINVPLVAGIMPVANAKQIRKITSMCGCSIPEKFQKILNRYEDNPKA
LKEAGTAYATEQIIDLITSDIDGIHLYTMNKVDTAKKIMANIAHIREISGGSR
>A0A1M5GX30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenibacter palladensis|TrEMBL
MFRGINKIIANGPFLWKRIEGEIMKVTEHIKKAEGKTLFSFEIIPPVKGRSIQELYDNID
PLMEFKPPFIDVTTSREEYVYIDRNGLLDKKLTRMRPGTVGICASIQHKYGVDTVPHVLC
GGFTKEETEYVLVDCQYLGIQNVMALRGDARKEEQYFNPTKGGHAYASELVKQIYALNQG
NYLHDKVETVHSADFCIGVAGYPEKHLEAPSLITDLKRLQEKVEAGADYVVTQMFFDNQK
FFEFVEAAKKMGINVPIIPGIKPIAVKRHLQLLPQVFKIDLPQDLIDAVEGCSTNADVRQ
VGIEWAIQQSKELKAAGVPVLHYYSMGKSDNIEAIAKELF
>A0A2S4T7C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ABNIH27|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A7Z9XJW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MQFKAIYRTAQHPILSIELFPPKTEKGRAHLEKELAQLMQHQVGFVSVTYGAGGSTQNNT
LDLVKRIRAQYGVTTVPHFTCVGASRQSILAYANRAIAEGAENMVALRGDPPRGQTTFVP
APDGFRYAYQLVVFLKERFGDRLSLAVAGYPEGHVETRDLATSIEHLKIKVDAGADLVIT
QLFYDNADFFRFRDMAVKAGINVPIVPGLLPITKYSQIDRITKLCGASIPADLTKLLLSF
EDGSPDQQMAGIAAAIDQAGELLENDVPGIHIFTLNNSFATAHMVEALGHYFE
>U3Q5B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blattabacterium sp.|TrEMBL
MKVTEHIARAKKSLFSFEILPPLRGRDIKDIFSTLDPLMEFCPPFIDVTYHREEFIYVEK
DNGLLQRRKISRRPGTVGICAAIMNKYGIDAVPHLICGGFSKQMTENALIDLNFLGIDNV
LVLRGDPLKSEKNFIAQKDGHKHAIELVKQVQNLNIGKYIDKTFVEEKKSTSFDFCIGIA
GYPEKHLEAPNIESDLFFLKKKVEAGADYIVTQMFFDNKKFFSFVERCRLEGISVPIIPG
IKPISSKKQLNGLPSRFYLNIPNELVKEIEKEKDKKNISHIGIEWAIHQSQELKNSGVEV
IHYYTMDKPENIYKIVQAIY
>A0A7W1TBD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRLDQILAAKPATLSFEFFPPKNERAWFTLEDTVEQLAPLGPDFVSVTYGAGGSTRGKTR
EVIEHIQGRSGLTAMAHLTCVNATRAELATLLDEYHAAGIANLLALRGDPPKGQERFVPT
DGGCAHAIDLIHLIRADGRFTALCAAFPEKHPDAPDRASDWDHLADKLAAGAAAAITQGF
FAVEPYLEMRAHVAARLGRAPRIIPGIWPVTGWKSVQSFCRFCAAAEPEELRALLQPLEA
DPVAARQAGIAFTVAFCRRLLAAGAPGLHFYCMNRSTAAAEIVTALRLGGAAI
>A0A353SYG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPIFTPGRRWQPPFMPFKREKFGKRALASLEKAVKGPLFGCRMCGNCLLQETAFICSMEC
PKGVRNGPCGGSTPEHCYVDETRPCMWYEIYDRAFKMGREEMLLEVLPPLDWEKVGTETW
GDVTRQVKKVGTGKVISGLISGDPVKRTTTWDLVFRPVRQPEWWAGDSDYHPAKYDEPVS
ELERRLKAGQFVVTSEVAPPVTIATKKLISNIELVKPYVAAINFTDCPSATPRMSSWSCS
ATAIKQNAEPVMQIAARDRTRVGLQAEVMGAYNLGVRNILCLSGDSMSMSPSPRGRMDIV
DLDSIQMLWILRRIRDEGKYLDGREIKTPPKYFLGAAASPFASDPRFQAIREHKKVNAGA
QFFQTNLVFDADGMEIWLNELAKRNILDKVYILVGITPLKNLRMATYMNDEVPGVFIPDP
LLKRMEKAGDGAAEEGLTIALELVEKIRKIQGINGLHIMAVGWEEIVPRLVTEAGLLPEG
FVQPAA
>A0A7C3Y508|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTTALPQTALNGAGSNLARVLRAGHCAVAIEVSPPVGPNVEFIERYIGVVRGYADAYNVT
DNQAASVHMSSLAVSIMLKQAGLEPIVQFACRDRNRLAIQADLLGAAAFGITTVLAISGD
HPRWGDHPQCKPVYDLDSMNLLRMIRMMRDNQVFENGAKIPRRAPDFFIGAVENPFAPPY
EFRPYRVAKKIVAGAQFIQTQLIYNVERFEEFMKRIVDLGLHEKVAILAGVGPIRSIRVA
EYMQKEVAGMDVPQWIVDKMRGLSKEDGEKLGIDLCLAMAKKVRT
>A0A7V7MI06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MQAQRQPTSKRPDIRTFLQDHVLVLDGAMGTQLHERGLSFQDCFDAANLSRPELVLEIHR
AFIEAGAQGIQTNTFGANRFRLAGHRRDDQLPLILEKALEIATEAAGDEVYVLASLGPLG
VELEPIGRLDRKEARDAFQQVARVLEPGVDGFSLETFGRLDEVLEAVRAIREISDKPIFA
HMSVDSRGLTGYGTQVETLGPRLAQAGADVIGLNCSTGPRAILESILRMVEYTDRPLSAR
PNAGMPREVDGRVFYENNPDYFARFARRFLQAGGRVLGGCCGTTPDHIRAMARSAKAIGI
QVRRQPLQVSQPLQGSERPRKPCPLSDRSKLGQALATGQTATSIELLPPRTPNMQALCEE
AKKVHDAGATVVNLPDGPRASARVSNLATAVILEREVGVETLLHFCCRDRNLLGMQSDLM
GAAALELNNILVVTGDPPYLGNYPDVTAVFDVDSIGLCNILDNLNHGLDLGGNAIDQQTH
FCLGAALNPTALDLDREIARYRWKVDAGIDFSITQPIFDVPSFLEMLDRLPEDGPPILAG
IWPLRSLRNAEFLAAEVPGVSVPEALLDRMREAGRRGREAAAEEGVAIALEAVEALATRV
EGFQIAAPFNKAEPAIRVLKLVQSIGGPQP
>A0A838PIV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrinomonadaceae bacterium|TrEMBL
MQSFRELLESDRIHVFDGAMGTMLYAKGVYINRCYDELNLSSPDLVREIHAEYIHAGADI
IETNTFGATAYRLHQYGLEGNLEEINIAAARIAREAAGEDAYVAGAIGPLGLRIEPYGPT
SFDEAKDMFKAQASALLEGGVHLFLLETFSDVSEIRQAIRAIRELCDLPIIAQMTIMTDG
NTTFGTTPEVFTARLDEWGADVIGLNCGVGPAIILSGLEKMRTVTKKKLAAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRLIQSGAKFIGGCCGTTPAHIKLISDAVRAASPRAQKMVMS
TGPLVQVQEIIPADIKVVPADERSNWSRKIVRGEFVTSVEVLPPKGVDAEKTLDSIRLLK
DAGVDGVNIPDGARAQSRMSALATAVLVEQQIGIESVLHYCCRDRNLLGMMSDLLGASAL
GLRNLLLITGDPPKMGPYPDATAVFDIDAIGLTNMVNKLNHGLDIGNNPIGQPTAFCIGV
GVNPGAINPEEEIRRFEYKVEAGAQYAITQPVFDTDQLRDFIKSIEHVRIPIIAGIWPLV
SYRNAEFLHNEVPGVRVTPSIMERMRAASAISKEAGRDEGLKIARESLLDVHDLIQGVQV
SAPFGNVKYALEVFGALEGFGGSEETALPADA
>A0A2S0JSC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. B2A1|TrEMBL
MGLLEKLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLEEI
LATVEEQATVLLAGNPDGLLLETYYDFEELTATLKMLRAKTKLPIIAQVSMHEPGVLQNG
KSLNYALHELEALGADIVGVNCRLGPFHTIQAFEGVELPEKAFMSAYPNASLLDLEDGRV
VYESETDYFGRAAVALRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVEEKLAKPEKVEI
VREAEPSRFEPLHLKVKRQRSVIVELDTPRHLEIDGFIKGAKKLYEAGADVVMMADNSLA
SPRISNVAMGALLKETHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRQKANFSVAAAFNPNVRVLDRAVSR
LEKKIEHGADYFISQPVYTKEKIIEIYEATKHLEAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSEEALARMKACGEDKERATLEGIAIAKELVEVAAQYFNGIYLITPFLRYDMTLELMKF
IEQLDEQKKGVSING
>A0A660VIQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MTTFSDSLAKNDGRTTLVELVPWAGPLQDEAGERHRQTARELSADPRITALTVTDNAGGF
VRLGPHTLGQAIQAMGGEVVVHLACRDRSRAALQSTLYGLASEGLTNTLALSGDYPKEGF
RGRSRAVFDIDSVGLISMLRDAGERGPRFTIGCAINPFKAAEADLVPQYLKLAMKVRAGA
DMAITQVGYDARPWSELLQWNATQGPGIPLMASVYILTKGVAKVFHRDGVPGIRLTDELL
AWAEEQAAADDKGRAAFLEFAAKQVAVVRGMGFAGAYIAGQRNVTEIDKILAMADEFESD
WQALLPDISFAEPGAQRLYQPGDLPQLASDQPTKPTKTRRVPLKYRVNRIVHDVAFAPES
RGFDVARGVYGRLESAHLMWPAHVLEQAVKIPMFDCQDCGDCSLPDIAYQCPEGACAKNQ
RNGPCGGSLNGECEVPGKRCVWANAYDRLRPYGEAMTMLDREPVLQDNALRGSSAWANTF
MGRDHYAHNTEGEDS
>A0A0R1XBJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limosilactobacillus panis DSM 6035|TrEMBL
MGIDHLSQVLAELQDLDPAFISVTCSSKTSQLAKETVKVADYVQNQCQVPAMAHLPAWYL
SKADVDRILEQLRAYHVNRVLVLRGDERPNLQKKNDFTHASDLIAYIRQNYPDFQITGAC
YPEKHPESLNMVDEIQHLRLKVAAGCDQIITQLFLDNQCFYRFRELCAVAGIEVPIIAGV
MPIVNERQANRILRTSAVAVPEKFKNILAKYRDHPQALKQAGITYAIDQIVDLVTNDVAG
VHLYTMNQADTARQIKQNIGSLFQVQCEGAK
>A0A6M4PDC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. jing01|TrEMBL
MDPALLDDFSLEMTGKDVPGLEEARDGIPPGTRINITFLAGEDTGTRLAAARAVRRLGFV
PVPHIAARRLPSRSALEEFLAGLAADGTAGNVFVVGGDPARPEGPYEDALAVLRTGLLRP
HGVRHVGVAGYPEGHPGIADRLLWPALTDKAAALGADGFTGDVITQFGFDVDPVLAWLEA
LRARGVTLPVRVGVPGPAGVRRLLRYAGRFGVGTSASVARKYGLSLTNLMGTAGPDRFLH
ALADRYDPARHGTVKVHFYTFGGLRTTADWITRFRRATEHLSEARQTARS
>A0A3R6UUI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OF09-10|TrEMBL
MNLREYLKETNLITDGAFGTYFAAKYQTQEIPELANLSDPEKVKKIHEEYLNAGANFIRT
NTFAANTETLQERFPEVEKNIRAAVEIARSAADGKNVWIAGDIGPIPVNGTEDAAAAADE
YYQIAKTFAETGVKVLDFETFADLDGILPAIKKIRAEYDMFIAVSFSVNQFGYSASGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPVYFAEKMKELQELGADILGGCCGTDPEFIREMSARDGILKKSAPEKEAESSGQSEH
VVRQGFLYDENGNRKEKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMANKVRQATGLNVMPHICCRDRNAIAMRSLFLGAAINDIYNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFANNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTEEDAARLRRIKDETGARILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKASRKEGEAVGIQLAKEVMKLVEDFADGYYFSFPFNRVYMLKNILEK
>A0A3L7PS73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSILHSYPPGRLGLSFELFPPKTAESEAAMWRTVDDLVAWEPALITCTYGAGGSTRGKTL
EILAGLRQRYGIAVASHLTCVGSTVDELRGYLCEAEALGVTAVVALRGDPPKGETAFQAV
DGGLSYASELVALIRAEFPRFGILVAGYPETHQEAVSPQADLDNLKRKVESGGDVIVTQL
FYDNADFLRFRDACRRLGIQAPVVPGVMPVTNFAQIRRIATLCGARLPDSFTRAFEAAGD
DEAAQFEAGVDFAAKQVEELVAAGVPGIHFYVLNKSPATTRVLEAVGIGGRKG
>A0A0F7GGU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalogenimonas sp. WBC-2|TrEMBL
MNVRDIYQKEKGIVFSFELFPPKTEESAAELFDTIKALKPLELSCVSVTYGAGGSTRELT
HDLLVRIHKETDLTVISHLTCVGSTIEEIRHILEKYRESGIENILALRGDPPKGQMSFVP
EVGGFSYAIELVKFIKTNFPEMGVGVAGYPEGHPQTPNRLKEIDYLKAKVDAGADYICTQ
LFFDNRDFYDFRERCALAGINVPIVAGISPITSVKMMKRMADLAAGTHFPAPLLRAINRA
EDEECVRDVGVHWAAEQVRDLVDKGVDGIHFYTLNSSDATLQIYKTLGVTTSKNLA
>A0A356NQM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
GDPPGGKGDFQATEGGFTYSKDLVAFVRSEFDFSIGVAGFPEGHIACKEGREVDWDRLKE
KVDSGADFIITQLFFDNDDFFRFRDHLVKKTGMTKPIIPGILSVLSTRQIKRFTELCGAS
IPESMLNRLDDLAEDDAAATEFGIEHAVRQCEALLDAGVPGLHFYCLNKSYSTNRIVDAL
SRYR
>A0A3D3XD86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MEFIKDIHREKIATGKPAISFEFFPPKTEKGEAQLFHAVLPELLKIQPDYCSVTYGAGGS
TRGKTLEMVSRIQKDFQLTCMSHLTCVNATREEVNQVLIEANKSGIKNILALRGDPPGGK
GDFQATEGGFTYSKDLVAFVRSEFDFSIGVAGFPEGHIACKEGREVDWDRLKEKVDSGAD
FIITQLFFDNDDFFRFRDHLVKKTGMTKPIIPGILSVLSTRQIKRFTELCGASIPESMLN
RLDDLAEDDAAATEFGIEHAVRQCEALLDAGVPGLHFYCLNKSYSTNRIVDALSRYR
>A0A1G6T0H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia lycopersici|TrEMBL
MKPIELSFEFFPPKTPDGVEKLRATRAQLATLKPKFVSVTFGAGGSTQQGTLDTVLDIAK
EGVEAAPHLSCIGSSKESLREILGAYRAHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IREETGDAFHIEVAAYPEYHPQARSPRHDLEAFAQKVKAGANSAITQYFFNADAYFRFVD
DAQKLGVDIPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTGLCRRLVDAGVPGLHFYTLNAAPATKAICERLGF
>A0A3D3LHB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHIADILSQQKPTLSFEFFPPKTADASEALYQTIGELEALQPSFVSVTYGAGGSTRELTH
DLVVRIQKTTRLDPVPHLTCVCHSEGDIQAILERYAQAGVSNILALGGDPPRNLEGYERK
NDAFQHAADLVRFIKKFNDSGAHPDRRGFGIGVAGFPEGHPATPNRVLEMEHLKAKCDEG
ADYICTQLFFDNHDFLDFRDRCRLAGVHIPIIAGIMPITSAAGMRRMAELAAGARYPAKL
LRAIQRCGNDEEAVRRVGVHYATEQCLDLLGHGVDGIHFYTLNKSQATREIYASLGIRDS
ADVRKP
>A0A2E6D695|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRIVDLYGQGRPVFSFEFFPPKTDAGENKLMETMADLKSAVEPDFVSVTYGAGGSTRDRT
HGVVTRIQNELGITGMAHQTCVAASRTDVLKNVKRLAASGVQNVLALRGDPPDTDGDWQP
PADGFSHANELLEFLTAEFDLSLGAACYPEVHPEATSAEDDLAWTREKVKSGAGFLTTQL
FFQSDCYVQFVEHAREAGISVPIVPGIMPITNLGQIERFTKMCGAELPAELRMRLQRCGD
DAAAVMATGIEHAITQCRELLEAGAPGLHFYTLNKSHATRSILAAMRQL
>A0A2N2V0C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-12|TrEMBL
MKPEISIEFFPPQTPEGVDKLRTVRAELAQLKPAFFSVTFGAGGSTRERTFSVVKEIAAE
GHDAAPHLSCIGSTRASIREILADYRAAGIKRIVALRGDLPSGMAETGEFRYANELVEFI
RAETGDWFSLEVAAYPEWHPQARSPKDDLDAFVRKVKAGANSAITQYFYNADAYFSFVEE
ARALGADLPIIPGIMPIVGFTKLARFSDACGAEIPRWMRKKFESFGDDADSIRAFGLDVV
TDLCERLLKGGAPGLHFYAMNQSALTKEICRRLG
>A0A2A3AD63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria sp. WRN011|TrEMBL
MPALSTPQISEQTVTTGPPTGTSWLVRRPRRESLISFEVFPPHPTRDPEAVWRNIDTMAA
AGPDFFSVTHGHSGTNGVSRETLRHLLKQTKTPAVAHLTCGGTDRAGLERAVEDLLDDGV
RDLLALRGDPPVGGGEWVTHPGGFDRASQLVELIREVEERKFGACERPGKRPVSVSVACY
PVAAKGRDFEADLAALWDKQQAGADYAITQVLYDAQDYVRFLERARSEGIHIPIIAGLVP
LTDIKRLGRMTELTGVPIPERITKFLDTDHPGELRRRGIAATLTLIDELLDFGCPGLHLF
TFNRPDAPLAILDHLRVRDAAREFRGSSSAA
>A0A246RRZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora wenchangensis|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTAQGERLLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVR
GDPPGDPGGEWVRHPEGVDYAEDLVRLVREAGDFSVGVAAFPYKHPRSADVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQASEMCARLLDEGVPGIHFITLNRSPATREVWRSLR
ADARV
>A0A0D0H918|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter komagatae|TrEMBL
MTASLLTGSAPTRARFSFEVFPARSGAAALALGSSVQHLSAAGPDFISVTYGANGSNRDA
SLDLLAYLRDHTEALPLAHLTTVRESREVIRETIHRIMDAGIHDFLALRGDPPRGTDEDD
PEVAGSLSALELTELIAEARAERPAFTSVGRTAVAAYPNGHPLSQGQSADIDWLLAKEAA
GAQFAITQLFFRAEEYLSFADAARSAGLTMPLLPGLMPVSTSGQLRKVASLAGRPAPVAL
ERALEEAGGFAPELGVEHTVSLARELLEGGAPSIHLYTFNRHEQVLAVLAELNLLEG
>A0A1S1X3D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium sphagni|TrEMBL
MTQTPRTFSFEFFPPKTPEGIAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGQAAAPHLSCIGSTRENIAAILDEYRNNGIRHLVALRGDIPSGMVAAGEFRYANELV
SFIREQHGGHFHIEVAAYPEFHPQARSAEDDINNFVRKVRAGADSAMTQYFFNADSYFRF
VDEVRARGVDIPVVPGIMPISNFGQLCRFSDMCGAEVPRWLRQRMQAYYDDTASIRALGL
DVVTELCDRLLQGGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A3D4JH78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
TEKMKNNINMLKQYVTALNFTDNASAVPRMSSVACSKIALELGAEPVMQLSAREKTRVGL
QSDVIGASALSVPNFLCLTGDSMMMSPGPKGRMDIVDIDSIQMLWILRRLRDEAKYLDGR
EIKNPPQYFLGAAASPFASNMKFQALREQKKVNAGAQFFQTNVVFDADDLDNWLNEIAKR
DILDKVFILIGITPLRSFKTAKYMHDKIPGIFVPEKIMQRMEVADQKGNAEEEGIQIALE
LVEKIKAKQGVNGLHIMSVGWEEAVPRIVEEGVREQQI
>A0A3D4JC40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MSVFTPGRRYQPPFMPFKRQPFKKRLLASIELAVKGPLFGCRMCGNCLLAETALICPMEC
PKGLRNGPCGGSTPEKCYVDESRPCIWYKIYDRAFKLGREAYLLEVLPPMDWEKAGTDSW
GGIIDNAKQIGVRTIISRLASGKPDSVSSTMVSILRPVRQPEWWQGDSEYHAPKYSEPVS
ELERRLKAGEFVVTAEISPPLSVATEKMKNNINMLKQYVTALNFTDNASAVPRMSSVACS
KIALELGAEPVMQLSAREKTRVGLQSDVIGASALGVRNFLCLTGDSMMMSPGPKGRMDIV
>A0A2E3A1Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRLIKDIYXDKEALGKPTISFEFFPFKTPEGEVRFFDKTLPALMEARPDYASVTYGAGGS
TREKTLEIVEKIQGDFGLTTMAHLTCVKHTIDEINSILDDAKNRGIRNILALRGDPPPGE
NWSMTDGGFEYASDLVSYIKAQGDFGIAVAGFPEGHIDCKDGKEVDWQYLIKKIKCGADL
VITQMFFDNSDYFQLVDFLKEVGVNIPLLPGIIPVDNASQIKKFSAMCGAKLPKKFTTRL
EELGDDSDAVREFGIEYASLQCQELLDNGAPGLHFYTLNKSKAVCGVLSNLNLA
>A0A352CKC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIEHINQAKDTLISFEVLPPLKGKGIGALYKHLDPLMAFKPAFINVTYHRSEHVFKKK
ADGNFEKVVVRKRPGTESICAAIMNKYNVDTVPHLICGGFSINDTEDALINLHYLGIDNV
LVLRGDAAKNESAFEPEPGGHRYAVDLLQQVSALNNGIYLEEELKDTQKTKFCIGVAGYP
EKHFEAPNMDTDLRHLKQKVEAGADYIVTQMFFDNAKYHDFVKACREIGITVPIIPGLKP
IYSKKQLTVLPKTFHIDLPSDLANAVQKCKTDADVEVVGKEWLLTQSRELKKSGVPVLHY
YTLGRPQLVADVVKDI
>A0A523TT29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MAELLSGSNLERVLAAGKFAVTAELGPPMDCNGEVVREKAKILKGNADAFNITDNQTAVV
RMSSIASAFIILQEGLEPVMQMTTRDRNRLAIQADILGACALGCKNCLCIAGDHQSFGGA
GRLKGHPGAKNVYDIDTIQLISALKGMRDDGVQQGGDPIDKRPPLFIGCAWTPMGDPIEI
RPTRLKKKVDAGADFIQTQGVYDVEAFKEQMKIVVDMGLHERTAILAGIIVPRNFGMLKY
MNNFVSGVSVPKELMDRMKAAMKAGGDDKKQKRINQEEEAGKITVELIQQCREIPGIKGV
HLQAIEWEKKIPEIVEKAGLLPRPTFD
>A0A0P0DIA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. DS20|TrEMBL
MMTGSSTNLAEARALLLSPLGPVARAGSNRETVRVSFEFFPPKTDEAEVNLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIIAETALRPAAHLTCVDASRDEVDEVIAGYKTIG
VDHIVALRGDPPGGGGIGGVYQPRADGYANATELTAAISRIGGFDVTVGAYPEKHPESPS
IDHDIEVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLV
RMCGACGAGIPDWLKAHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETKAVA
>A0A2E5ESX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDIHAERHAENKPCISFEFFPPKTAEGDKALLEKHIPALMELKPDYCSVTYGAGGS
TKEKTADIVESVQNQHQLTTMMHLTCVEATRSELEGVVADAKNRGVKNVLALRGDPPGGG
EFRVAEGGFEFSYQLVEMLKEQGDLSIGTAGFPEGHIHCTEGKYVDWERLANKVRCGADF
VITQLFFDNADYFEFVDHLRDKHGITVPIVPGVLPIISAGLIKRFTQLCGAKLPDPLVEQ
LEACANDDEVKEFGIEFATKQLKELIDRGAPGVHFYTLNKAYSTTKIMQNLGLA
>A0A7W4JYJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconacetobacter dulcium|TrEMBL
MNNTVKHRPTQALPGAFSPHALDMPPPALSFEFVPPRTDAQAHRLWQCIRRLAPLSPRFV
SVTCGAGGSPRASTRATVLRLKRETDLVPAAHLTCVGASRKEIDEIAHSYWQAGVRHIVA
LRGDPPAGAADYTPHPGGYAHASDLVTGLRRIADFEISVAAYPETHPAAPSPAFDLDNLK
RKLDAGATRAITQYFFDAETCLRFLDRCMAAGITAPIVPGIMPVSNYDQVARFSALCGVT
VPAWLTHLFEDTAKNPDLRRIVASVVAVEQVRALQANGINEFHISTLNHADLPFAIAHIL
GLRPTEASAPAESLTGNVL
>W4BIN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL R5-808|TrEMBL
MKPDLRQAWENQVLVGDGAMGTYLYQKGFPVGISYEELNLTSPEVIGNVHRQYVEAGAQV
IETNTFSANYDKLSKYGLETRVEEINRAGVRIAREAAGNHGYVVGAVGSIRAGKRNNIST
SELKRYFEEQLKVLISEGVDGILLETFYDVDEMQLALAQARMLSDIPVICQFAVEDIART
LDGFTMPDAYRILSQEGADIIGFNCRTGPNGIMRALETLNGVMNLPASVYPNAGIADYVD
GEYRYGASPEYFGKTALEFADRGARIIGGCCGTTPEHISEISLALSGYVPSPLPVVEEAE
VNRIVIHESAQEQFYERSGEPTIVDIVKERHTVIVELDPPRDLDITKFMKGAEALKKAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVVGAAFNP
NVRHLDKAVARLEKKIASGADYVMTQPVYDPELMVRLREATAHLEIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRMRMAGLEGEAGRAMGVKIGKELLDVATELFNGIYLMTPFMFY
EMSVQLMEYVWEKSGRRLTPLFH
>A0A2R6G0G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QS_3_64_16|TrEMBL
MSLEPRRTTTADGVSTLLAEPRFELMPFDSFGEQMDHLPDGAAIAITTSPTLGLDATLEW
SERAAERGFAVVPHIAARYVRDEEHLEEIARRLTDAGVNDIFIPGGDREDPVGEFASAYE
LLVALDGLEYTFEEVGITGYPEGHDFLEDRTLREAMERKEPYATYIVTQLCYDPDAVIEW
IEGIRARGIELPVEVGIPGVMNYGRLIEISRKVGVGDSVRFLRKTTGVLGFARQLLGSRG
KYTPDDLVEGLAPYAEDSDYGIRGLHVYTFNQTPDTEDWRRRTVGG
>A0A847VIN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MSFEFFPPNTPVGDAKLEQVVRDLAAVQPQYFSVTYGAGGSTRDKTLATVRDIAALGHEA
APHLSCIGSTRRSIAELLDTYRAQGIRRLVALRGDLPSGAVTAGEFRYASELVAFIRGTQ
GGDWTIEVAAYPEYHPQQRHARKDLEHFAHKVQAGADAAITQFFYNADAYFHFVDEVRRL
GVGVPIVPGVMPFHNYARIAQFAARDGIEIPRWVALKMEGYMDDAASIRAFGLDVVTGLC
RRLIEGGAPGIHFYTLNQSALSLEVCRRLGY
>A0A7L2EMK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anthoscopus minutus|TrEMBL
MVNETQHTCSASSSSRSDGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFVKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
DLAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A524CQF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MKKKKRRRKVKMSNRPAYSTLCQKIKEGHFVFTGELEPKKILNLDEIVDSAKEMKRTKKI
VAANVTDGPQGDAYMCSMVPSYKVQEEADIEAVWQVTVRDRNRVALFADVLGASQLGIKN
ILTLTGDHTALGDHKKGRAVYDIDSTQFCEMLSIMIDEGTDLNGNELKGGKIEMNYGCVA
NPNSDPREPEILKVGRKVEQGVDFIQTQTAFDIDQAIEFLKELERYNVPVLLGVFPLKSY
GIAWYFDNYIPGVSVPKDLLKSLKNAEKENKGNKPAKYEAIDKINIEFFKPFIEEIKKST
KAAGIHCMAVEYERLFEPLLSEFPEYVD
>A0A857SJD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus vulgaris|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTEEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASREELQHIAQDYWQSGIRHIVALRGD
LPDNTQKPDMYATDLVHLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMFD
GLDNDPETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPELVQA
>A0A8J8MM04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vallitalea pronyensis|TrEMBL
MHIKEYLKHNILVVDGAMGTYYAMKTAEDTTLAEKANLHNPHIIEEIHQEYIAAGAKLIR
TNTFSANTVSLNCDEAMVRAVLREGYRIAEQCATGHGIFVGASIGPIPEKERDMDALVVE
YKMIIDTLLELGNELFMFETFSSIKYIKILADYIMGKNKEAEIMAQFSVNAFGYSKEGIS
ARRLIKDARQVPGLVAYGFNCGIGVGHLYKVIKSLALEDENIIAIPNAGYPDKIFERTVY
RDNAKYFAESMMDIRQLGIKILGGCCGTTPKHIVSFINQLHEDYRPVSIKKHKHIVEIKK
KTKKNNAFFNKLSKGEFVVAVELDPPFNSQVNRIMEGAHQLKAEDIDIITIADSPLSRPR
ADSVIIASRIHRETGIDVMPHICCRDKNVIGLKSTLLGAHIENIRNVLLVTGDPIPSEER
SETTSVFNLHSIKLMALVNELNEALGAEDPFVYGGALNLNVKDVQRIIPRIKKKQASGAR
YLLTQPIYDEKALDNLRIIKEQVDIKILGGILPLVSYKNARFLNNEIAGIEIPECICSKF
TKDMSREEAQDVGIEIAMAMARKIKAVADGLYMMTPFNRFEMVSRIIEGVK
>A0A147K3N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hadesarchaea archaeon YNP_N21|TrEMBL
MRIKNIFAAKRPVISFEIFPPKSGDVIGIISGTLGRLKKLGPDFISITYGAGGSTRENTV
KIASLAKNRFKMEVLPHLTCVGHTAQEIDDILGALQAEGIENVLALRGDPPANSENFDYG
ANEFKYAVDLVRYIKSKTDMCVGAAAYPEGHVQSKRLSTDLAYLKQKVDAGVDFLITQLF
FDNRVFYNFLENARRIGIECPISAGILPVLNAHQVRRISSLCGASFPAKLLMIIEEHAND
PKEMEMAGIEYASQQVQDLLDNGVDGVHLYTLNRTEPIAEILRNVGLVNGDLQRHAHV
>A0A4V1TXD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
SGLQAFATKVRAGADSAITQYFFNADSYFRFVEDVQALGVDVPIVPGIMPITSSTQLMRF
SDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVITGLCEQLYAGGVPGIHFYTMNQAPAT
LELISRLRRG
>A0A1X1R4V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium fallax|TrEMBL
MSVVDRIAEIAVARTPFSVEFFPPRDEAGEAQLWRAARAFEPLDPAFVSVTYGAGGTTRD
RTARIVGELAATTSLLPVAHLTAVGHSVAELRELIDHFAAVGVHNVLALRGDPQGGVRQE
WVQHPEGLAYAVELVELITAAGGFHVGVASFPEGHPRAINLAADTANLVNKLRAGAEYSI
SQMFFDVEDFLRLRDRVCAADPEQGAKPLIPGLMPITSLRSVSRMVELMDSQIPTSVLER
LSRAAGDGPAENRDAVRRAGIELATEMSRRLIDEGVPCLHFCTLNFAKATSEVLTNLGLT
QSRVGSGAVTRGD
>A0A397I231|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus turcosus|TrEMBL
MEKITDKIAALPPDENYFSLEFFPPKTQMGFANLTARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNRDFTFAVDLVRYIRKKYGDYFCLGVAAYPEGHPVDSYQDVQDPARDLPYL
VEKTQAGADFIMTQLTYDIDAYTKFEEMLRNHESGAFKTIPIIPGLMPIHSYKILTRTTK
LSHVRIPPQIMSKLDAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLNLEKT
VSFIIERCGLIPDDPEDSGAVADDDYATAPNGAQIRSLDRRRASSINSQPHNRVIVDRLQ
IPSDGSSRASTTHEVPATSAGMPAMPPDRNTTLQISEGNGALGREATWDDFPNGRWGDAR
SPAFGEIDGYGPSLHVSATVARRVWGYPVSREDISTLFRRHVSGDLYIVPWSEGGAEENS
SGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEF
FCPTKDFQTVLKPLFAKHGHEKLAWFATNAKGEFESSLPADPADADTIEMNPNNVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAYRIWDEWRRVYPRGTPTERFLDEVKNDVWLVCVV
GQDFGAGTENGSEEEQHETKWMWNVLINSQ
>A0A161XFM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium magnum DSM 2767|TrEMBL
MSLLKEALERGEFAVTAEMAPPKGIDLSHLIECAKMIKGRAHGINVTDFQSATLKATSLA
TCKVLKDAGFEPILQITGRDRNRIAIQGELLSAGVFGIENVLGLTGDYTMVGDHPGAKPV
YDLDSVGILKVASTIASGKDMSGNDLSSTPNFYLGACVTPKYDPLELQIMKMEKKIKAGA
RYFQTQAVYDMDTLRIFREKTKHLDAKLLVGIIPLKSAGMAKYMNKNVPGIFVPDELIER
MKNAEDKVKEGIQIAGEFIKQAKEEGLCDGAHIMAIGAEENVPLVLDAAGL
>A0A1Y4UMS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tyzzerella sp. An114|TrEMBL
MKIKDILNSKKVTLSYEVFPPKAGASFEPVINAVDELCKDKPDFMSVTYGAGGGTSNNTV
KIASHIQNDLGVTALAHLTCVSSTKEQVAKAIDEIKANGIENILALRGDIPKGGEYPVGE
YYKYASELVKEIKSKGDFCVGAACYPEGHTECEHKADDIRNLKIKVDSGVDFLTTQMFFD
NNVLYNFLYRIREQGITVPVIAGIMPVTNGKQISRICQLSGTYLPARFKAIVDKFGDNPE
AMKQAGIAYATDQIIDLVANGVKGIHIYTMNKPDIAESIKKNLSYIIGDNQ
>A0A497TTL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium endosymbiont of Escarpia laminata|TrEMBL
MTTKRSFSFELFPPKTEKGFENLKSAVNQLNALNPEFFSVTYGAGGSTQERTFASVDWLR
EQQIETAPHLSCIGSGREEILQILDRYHGQEIRRLVALRGDLPSGTGLGSLGELNYANEL
VELIKERYGDHFHIEVAAYPEFHPQASSAQTDIKNFKRKVEAGADSAITQYFYNPDAYFC
FVEECSGMGIDIPIVPGIMPITNYVQLARFSDACGAEIPRWVRRRLEGFGDDLESIRAFG
TEVVTELCRRLLDGGAPGLHFYTMNQAAPTLKIWKNLGV
>A0A1T4MGP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinactinospora thermotolerans DSM 45154|TrEMBL
MLGSPSRSGAPRGAAPRPRRISDLLAAGETTFSFEFFPPKTAEGERKFWRVIREIEALQP
SFVSVTYGAGGSTRDRTVEITERVATDTTLLPVAHMTAVNHSLRELRHLIGRFAGVGVTN
MLALRGDPPGDPLGEWVRHPEGLEYAEELVRLIKESGDFSVGVAAFPHKHPRSVDLETDL
EYFVRKCRAGADYAITQMFFEADQYLRLRDRVAAKGCDIPIIPEIMPVTKLSTIERSEQL
SGAPFPRRLAEEFERLGDDPEAVRQLGIEQGTRLCERLLAEGVPGIHFITLNQSTATREI
YRRIAGSRVPVGAASRP
>A0A4Q3RBL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MHLPLSFEFFPPKTPEGVVKLRTVRAQLYAMKPEFCSVTYGAGGSTQAGTFNAVREIQQE
GVDAASHFSCVGATRDTVRTQLAELKAMGVRRLVALRGDLPSGYGAGGEFQYASDLVAFI
REETGRDFHIEVAAYPEVHPQARSADADLQAFAAKVHAGADSAITQYFFSAEAYLRFVDD
ARAKGLSLPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVV
AQLCERLQAGGAPALHFYTMNQSVATLGVLQRLGWAA
>A0A0X1KP89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudothermotoga hypogea DSM 11164 = NBRC 106472|TrEMBL
MKLIDKLKEGPILSIEVLPPSRGHGVEEIFRTIDQLMEFPISFINVTRHAPELAYVESDG
QIVKVTKVKRPGTVGLAAALMHRYRIDVVPHVICYGMDKYQIEDLLIDLHLIGIRNVFVV
RGEYENPLSEQQDRSSYRHAVELVQHIANLNRGVYLYPTEGSEPTDFCIGVAGYPEKHFE
APNMEEDLMNLKRKIDAGAHYVVTQMVFDVEIYKRFVQMARSFGIHVPIIPGVKPVVNLK
SIYSIPKKFFVTIPASFVSQMHQASSSEEEFRIGVRFAAKLAEDLLAAGAPGIHVFTMGR
AKATKAMLQLLYSKQV
>A0A3M1C9B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrio sp|TrEMBL
MKKLLDEIGSRCLVADGGIATSLYDKGFYINRSFEELCLTHPKEVKDVHLGFKNAGAEIL
HTNTFSATEPKLIEYGIHEQLEDILKAAVELAREVSDGKTLVVGSIGPLGIVLEPLGPVS
IEEAEELFLKNIRIFEKEKVDAINFIGFHDLNELGAGIKAARQAFSGPIWAHIGVQENMR
TSYGHTLKEFVDLCEEEGVQVLGVAGEVGPSGALTALEQLKVLTSKPISLLPNAGLPRFV
NDQYIYLCNPDYLGKYAKRFALGGASVIGGHSGVSATHIQAVSNALKVVKAPAHEGENQK
EKSTNFLVEAVDKPQEPKPIEARSQLGKCLKEGTRVFTVEVLPPRGVDFSGFIKKCQQLE
NAGVRFVNIPDGARAVARMGSLELGSYILSHFHQLEPIPHVTTRDRNLIGLQSSLLGAFA
NGVRNVLLVTGDPPKLGNCPGATAVYDVDAIGLTHIVNRMNQGLDIGGSSFGKPAEFLIG
VALNPTAQNRKLEIQRFRYKVEAGADFAITQPIYDLNMYQKFMDELGDVSVPIVMGIWPL
VSFRNAEFLKNEVPGVFVPDWILEEMEKVRDNPQDSIKKGEEIACQVITEAKNFVAGFQI
SAPFNKVEVALDVIKKTES
>A0A7C0WE50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MLDTSNNRTPNGNSNELNVSFEFFPPRTRKMEETLWQAIRRLEPLGPRFISVTYGAGGST
RERTHATVARILKETALKPAAHLTCIGATREEVDAVIRDYWDLGVRHIVALRGDPADGEG
TPYTPHPGGYANAAELTAGIRRIADFEVSVSAYPEKHPDSPDFAADIDMLKAKVDAGATR
AITQFFFDNDLYFRYLDRVRAAGIGIPITPGFIPILNFRQVAKFAALCGTHMPSRIAARY
EGLDDDPETRKLVAATIAAEQASDLAAQGVTDFHFYTLNRADLVFAICHLLGL
>A0A8I1P5H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MQPGVHAAGAAVRIPASIEITPKQAVSLPELPGLFPPGVRVYIADIGIDGDDMLVQAARR
VTELGYVAVPHLPARRLGTKAALEARIKASAQEAGVRDMLIVGGGLARPAGEFGSTMDVL
ETGFMDRYGITDIAVAGHPEGSPDFGEREAIEALKLKQAFGERTGASMRIVTQFGFDGAA
FVRWAEGLRAVGVDLPVHLGVAGPAKVTTLLKYAAACGVGNSLDFFRKRFGSIAMLATSY
SPEEVVGPIEQHALRTADSAIRQIHVFPFGGPKKAADWLFGRGSWGVQMQDGTARRFG
>A0A6C1QIH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MTIPEHIAQSNGSPRISFELLPPIKGSSINTIFETLDKLMPFNPPFINITYHREEVSYMR
QADGNLKPAVVRKRPGTVAIAAAIQAKYKVDVVPHIICGGFSRQETEDALIDLDFLGIKN
LLVIRGDGDKITGRFKPNPHGHRYASGLIEQIINMNKGIYSEQYVQNPTHTGFSIGVAGY
PEKHPEAPNLDDDLFYLKQKVDKGAEYIVTQMFFDNQVFFNFVKRCREAGINVPIIPGLK
PVSIKEHLHVLPRTFSLTIPSALAKELQKCSDNNQVRDVGREWTTAQIKELHANGYPFSH
IYTMGKVDQIVKISENVL
>A0A3S8UFB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas entomophila|TrEMBL
MSLLKTTLDANAFACILEFVPKPSAERFATLDTLMARTQLCGWPLTVAIGDRVGSALDMS
PLDAFASLAEPVPALLHFSGKDRERRDLLAQLQRMDAAGLDQLLVLTGDRLPGHTPGQRP
VRYLESVAALQIVRQARPHWLLAAALNPFKYQEAEGGAQYFKAEKKLAAGADLFILQLGF
DIEKHQEAYDWMQRQPHPKPLMACIMALTEGRAGMLDHVAGVTVTPSMRALLAAETAVSK
QYAKDRANQRLALQVIGLKLMGYAGVHLSGIHDVAQFEALEQAITELQPLFTTLQDWTPA
WHAAWQEPGLPAVTFHPPGHAWRLGQRQITASKKEKARYHLLAAMHHQLFSRTTPLSKAF
GWAVSRPLWRTPAAAQWLHQLERRIKRPMVGCDTCGSCRLEDTLYICPETCPKGLANGPC
GGTRLDRCEFGDRECVHSAKYRLAVSVGRDEVLRERLIPCVQVQDRHRSSWPVWFEATTL
RSPSQLPDVAPEFNE
>A0A8F9ZQ15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. DSM 110487|TrEMBL
MGYEVIPFKRTEEAVLAHVPTDVRLTVTASPAKGQDVTVDLAVALAGHGYTVAPHLSAQQ
VRDRAHLAEVVSRCREAGIRDVFVVGGDRSDIRTEFADALTLLTALHELDHGFTDIGIAG
HPEGHPQASDNQLFQALVDKAPLATRITTQIVFDPRVILAWARELRRRGIKLPVQVGVPG
VVHRQKLLRVSGNLGIGESVNFLKQQQNLLWRFFLPGGYRPNAIIKGLAPHLGRPDTDLV
GFHVFTFNDLAPTEAWRRRMTANLA
>A0A7Z6TJ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ZS0098|TrEMBL
MTTFSFEFFPPKTAAGERTLWQAIRQVEPLRPDFVSVTYGAGGSSRASTIEVTRRIAAET
TLRPVAHLTAVGHSVAELRQIIGAYADAGIKDVLVLRGDPPGDPRGPWAAHPDGFTHAYQ
LVELVRSLGDFTIGVAAFPERHPRSPDWDTDIRHFVAKCRAGADYAITQMFFHVEDYLRL
RDRVAAAGCDIPIVPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAARDDRAAGHRIGV
EYATAMAERLLAEGAPGLHYITLNRSTAALDIHRNVISSRSIRVA
>I5BZT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor aquibiodomus RA22|TrEMBL
MPQQRFSRQPDVAGKLRVSFEFFPPKTDTMEARLWETVQRLEPLAPSFVSVTYGAGGSTR
ERTARTVRRILDETSLTPAAHMTCVDASREDVDQVVGEFVDMGVKRFVALRGDPSAGVGA
AYRPHPDGYANGAELVGAMKRQGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDHYERYVERARRAGIYIPIVPGILPVHNFTQVANFAGRCGASVPGWLAERFE
GLEDEPQIHALVASAVAAEQVLDLMERGIDDFHFYTMNRADLVYAVCHMIGIRPRPSKGL
EQPAAA
>A0A2P5I8X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diaporthe helianthi|TrEMBL
MDKITDKVAALPPDANYFSLEFFPPKTQMGFANLRSRLERMARALKPTFVNVTWGAGGST
AQKSMELAEICQRELGLTTCLHLTCTNMSRRLIDKALEDAKVLGIRNILALRGDPPRKEE
YRDENEDDDEGEDEFTWAVDLVRYIRKNHGDHFCIGVAAYPEGHADESHPLGQSMEHDLP
SLVEKVQAGADFVMTQLFFDIKAYDKFETTLRDHPSGAFKDIIIIPGLMPIQNYQMIKRT
TKLSHARIPDDLVARLDEVKKDDEQVKQVGVDILSELVEQIREIKSRTPGPKGFHFYTLN
LEKAVSFILERTDLIPPETPTEEAIVDDLIPLVPKIELNGSGSNHSSQQHLAVGHSSRRQ
SNVSSEPRNRVIMSGENRTPSNPEYEATQLEASRPFDPVHSRVNTLAISEGEGILGREAT
WDDFPNGRWGDARSPAYGEIDGYGVSLHMSVTQAQRLWGSPKAVGDINTLFIRHLRGELS
AIPWSEEEFNAETGTIKERLIELNTRGWWTVASQPAVNGLRSSDPTFGWGPANGFVFQKA
FVEFFCPAEDWKRLHEKLSKPEMKNSIWFYAANAAGDFLSSDFSGGLDLEMKEAGTNAVT
WGVFPGKEIITPTIIEEVSFRAWAEEAFGIWGEWAQVYGKGSESSKFLEEMKHGLWLVNI
IHHEYVEKDALWDLLASS
>K1GRC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis HMW 615|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A1V9ZFA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achlya hypogyna|TrEMBL
MKISEKIRAKLEKDEVFYSFEYFPPKTQAGVTNLYSRIDAMAQMDPLFCDMTWGAGGSTD
KLTLEISANVQKFSGLEMVMHLTCTNMSRGSILNALSSAKDAGIQNILALRGDPPRGKTE
FTECDGGFSYAVDLVKFIRAEFGDYFCIAVAGYPEGHPDSTDLDADLKHLKAKVDAGADF
IVSQLFYDAQIFLDFVARCRAIGITVPILPGIMPIQSYQGFARMSAMCCRTVPAAIHDAL
EPIKDNDEAVKDYGVKLGIQMCRQLLDAGVKGLHMYTLNLERSTRLILEGLDLISPARRE
LPWRPSTMVKRVAESVRPIFWANRPKSYLHRTASWDEFPNGRWGASESPAFGDLSESHYM
HATHSVADRKAMWGDAPVSLDDIYETFTRYCMGALKSLPWCDTPLHLETKSIQEMLAGLN
RAGFLTINSQPRVNAAPSDDPMFGWGGPGGRVYQKAYVECFVSPANLKHIIEAAAKLKWV
QYHAVDVHGNSYSNCGKGTTAVTWGSFPNKEILQPTIVDTESFMAWKDEAFSLWMSMWAS
LYVPDSPSYALIKEVHDTFFLVSIVDNNFVNGNIWDVFDTTADASAAPTATTP
>A0A1R0L3J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis coloradensis|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAVDEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTLRTLHTSIKLSGAPAPRRLLDRLEPLA
DDPKSFRSAGIDAVTELCERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A2N7RUX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. AD80|TrEMBL
MLSPLMPPAQPWPARDITHACSLEVSTKDIAALSAAASRILPGSTIAIPYLPREDDDARL
AAARAVRKLGFEPMPHLSARRIASRAGFESFVKRAAAEAGVERCFVIAGDPSTPVGPFCD
SASLIDTGVFERPGMRVIGVGGHPEGHPVMSKAEQWDVLERKCRSISARGMAPLIVTQFA
FDADIVLTWLTALRARGMHHRVRVGVPGPASIAVLARYAAVCGVGACASMWSKYGVSIGK
LFGTAGPDVFVDRLAAGLTAAHGEVSLHFFPFGGIAQSVKWVEQYRARTALAA
>A0A0C2BY52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noviherbaspirillum autotrophicum|TrEMBL
MTQQNFSIEFFPPKTPEGVEKLRAARARLAELKPKYFSVTFGAGGSTQKGTLETVLEIKR
EGHEAAPHLSCIGSSRDSLRAVLDEYQANGIRRLVALRGDLPSGYGASGELRYANELVEF
VRAETGDWFHIEVAAYPEMHPQARSPQDDVQRFARKVQAGANAAITQYFYNADAYFRFVE
EAGKVGVTVPIVAGIMPITNYSQLMRFSDMCGAEIPRWIRLKLASFGDDSASIKAFGVDV
VTALCERLLAGGAPGLHFYTLNQAAATMEICRRLNGSSR
>A0A2P7QU85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zobellella taiwanensis|TrEMBL
MGFHSARHVEALNQSLAELNGDINVSFEFFPPNSEQMEQTLWHSIERLKTLAPKFVSVTY
GANSGTRDRTHKVIKDIQDKTGLVAAPHLTCIDASRDELRAIARDYWNSGIRKIVALRGD
LPQGMEKPDMYAADLVGLLKEEADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVTIGIDVEIVPGILPVSNYQTLIKFAGFSNVKIPGWMHQRFH
GLEDDQNTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPRIAG
>A0A5C8C962|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp|TrEMBL
MTKHIPISFEFFPPKTDAGAEKLRAVHQELQRLNPEFFSITYGAGGSTRERTLAAIHDFN
AKGTPVAPHLSCIGDSKARIAELLDLYQAQGINRLVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGEHFHIEVAAYPEMHPQAANFDTDIQHFIDKVQAGANSAITQFFFNPDAYFYFV
ECLEKAGVQIPITPGIMPMTNASNLIRFADGTGAEIPRWIRKQLAAYGDDSKSIQAFGHE
VVAKLCERLIAGGAPSLHFYTMNNIEPTRQLVLDLGLA
>H1D1X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dialister succinatiphilus YIT 11850|TrEMBL
MSTLKEKHNQHIFTITTELDPPKSASSSVTEAQVVKVAPYVDAVNIADCPMAKMRMSPIA
LSSIIQSRYQVESIFHLTCRDRNVIGLQAELLGAYALGVHNILTLTGDPPSIGDHPDAKG
VFEVDSTGLIEIAKALNEGHDMMGHELGEAADFYIGTTANPGADDLDKEIRRLEGKKKAG
AQFIQTQPIYDIRQAENFLAAAKDLSLPILFGIVPLKSFKMANYLNSHVPGIFIPPAVMK
AMETGGRETGIALSRELVQALRDIHADGAHLMPVNDVDAVAEICRTHK
>V2PYW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucispirillum schaedleri ASF457|TrEMBL
MSISNILNTRNPSISFEFFPPKTLVIEKVLFDTIDSLQEEHADFSSVTFGAGGSTADKTL
DWINYIKDTCRYETMMHITCVGFDKVTLDNILEKLENAGIENVLALRGDIPKGSDLKQGD
FKYASDLVSYIAKRGKFCIGVAGYPERHPESPDFEKDIEMLKYKVDMGASFIITQLFFDN
EYFYRFRERAEKAGIKVPIVAGIMPIVNFSQIERFKVMCSSNIPENLIKSMQGKSEEDIA
SIGIDYAVNQCEDLVKNQVAGLHFYTLNRSHATKRILDKLHFL
>A0A0R2WZZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|OM182 bacterium BACL3 MAG-120924-bin41|TrEMBL
MEFFPPRTPAGEEKLDIVHAELSKLGPEFFSVTYGAGGSTRDGTKRAVTRFREAGSRVAP
HLSFGGSDEGDILKLLHDYKEAGIDRLVCLRGDAPSGMGSASLYRYANELVEFVRKETGD
HFTIDVACYPEVHPQSRSVESDLEFFKAKVDAGANSAITQYFYNADAYFGFVDDCARAGI
NIPIVPGIMPITNYANLARFSAACGAEIPRWLTKRLEFLEHDDHALREFGLDVVTDLCEQ
LLAGGAPGLHFYSMNQADSVTRLWQNLLED
>A0A3M0YJZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEYFANAQGQTLISFEILPPLKGGSVQDIFNVLDPLMEFKPPFVDVTYHREEFIYKK
MPSGYYEKVAIRKRPGTVGICAAIMHRYGVDAVPHLICGGFTKEETENALIDLNFLNVHN
VLAIRGDARKFDGKFIPEPGGHAYAIDLVRQIADMNQGKYLDPNIENGVKTDFCIGVAGY
PEKHFEAPNLETDLYYTKQKIEAGADYIVTQMFFDNKKYFDYVDRCRKMGIEVPIVPGLK
PITKAYQLTSIPRMFHVDLPTELVQEFRKAKTPEAQREVGIEWCIAQSKELKAAGVPCLH
YYTMGDVDTIRRIASAVF
>A8LPW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12)|TrEMBL
MSAPRVSFEFFPPQSIAASFRLWDTVRTLAPLDPSFVSVTYGAGGTTRKLTHDAVATIGQ
NYGLNVAAHLTCVEATRAETLEIAEGYAAAGVTEIVALRGDPPKGADRFTAAQDGFASSV
ELIEALAATGKFTLRVGAYPDQHPEAASADADVDYLKRKIDAGAHSAITQFFFEAETFFR
FRDRCAKAGIDAPIIPGIIPIENWTRARQFALRCGTKVPAWLDEAYAAAIRDGREDLLSI
ALTTELCTELREGGVEDLHFYTLNKPELTREVCAALGVTPKAGLAEVAA
>A0A6J4XNY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis Delta 1 endosymbiont|TrEMBL
MPTPFKEALDSGKFVVTSEVAPPKGTNLEKFKHHIDLLKDKVDAMNVTDHQSSVMRYPSL
GGCLLVKEQGGEVILQMTCRDRNRLALQADLMFASYMGVQNVLCLTGDSVMLGDHKQAKS
VFDLDSSQLLATVRTLEKGKDLGGNELDGKVDFCAGAIVTPEADPLEPQLIKFEKKIESG
AEFIQTQAVYDLDRFKEFMDYARQFKVKILAGIILLTSAPMARFMNKNIAGVFVPQDLID
EMASAPKGQALAKGIEIAGRMIKRIHDEKMCDGVHIMAIGKEEKVPDIMAAAGLI
>A0A143MKM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus subterraneus|TrEMBL
MGLLDELKQRILIADGAMGTLLYSHGVDRCFEELNLSNPDEIIHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGGAYVLGTIGGLRTLNKSVVPLDEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALSRLEALGADVVGLNCRLGPHYMIQSLEEVPLPNRAFLSAYPNASLPDYRDGRLV
YETNAEYFEEAAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTRRSVIVELDPPKQLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIVKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDVSSFDLIRLISQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPVYSEEKILQIYEATKHLATPIYIGIMPLVSARNAEFLHHEVPGIT
LSDEIRARMAACGSDPVEAAREGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A8H6FSP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Letharia columbiana|TrEMBL
MEKITDKIAALSNDANYFSLEFFPPKTQIGFSNLQTRLERMSSALRPLFVTVTWGAGGCT
SSRSLELAEICQRQLGLTTCLHLTCTNMKRKVVDEALEEAKVLGVRNILALRGDPPREEE
YRLEDEAENGKDEDDSNEDFTWAIDLVRYIRRVHGDYFCIGVAGYPEGHADQSHPTDQDP
LHDLPYLIDKTKAGADFIMTQLFYDVEAYSKYEKMLREHESGIFAQIPIIPGLMPLQSYE
ILMRTTKLAHAKVPLELLHKLQGVKGDDEAVKQVGVEAIHDVVESIREVKAKGPRGFHFY
TLNLEKAVSSLLDRCNLIPPDPDDNNVSAIDDVSILFNGNAAHHRALSSTSSSAAAQLTT
NSHRSSSPARFIPPNSNPLSREATWDDFPNGRFGDARSPAFNPPLTYSPTSLTISPAQAL
SLWSTPTTPEEITHLFISHLAGQTPKQLPWSESATLSPETALITSELTQLTRLKGYWTIA
SQPAVDGLPSTHSIHGWGPPGGFVFQKAFVEFFVPASTFHTTLRPHLDRLRKEGEISYYA
GNAAGEFQSSESSDAVHAVTWGSFAGKEIATATMVEEVSFRAWVEEAFGIWGEWGRCVGE
AARRGRVEKARQSRGFLRRIGKDVWLVNVIGHGYREGGRLWEVLMEA
>A0A402DJV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa NIES-4285|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGSLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPVHN
>A0A271KID9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium wenxiniae|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFAEMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A0F7SQL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaffia rhodozyma|TrEMBL
MTKVTEKIAQAEKENRTWWSFEFFPPRTAQGLQNLYDRIERMKGLGPEFLDITWNAGGRS
SDLTTSLVQVCQSHIGMETVMHITCVEKEKLDEALNTAKAFGCQNILALRGDPPAGSQVW
EPVPTGFKTAAELVRYIRQEHGDAFCISVAAFPGSHPETGPSEEEKEQEIEWLKEKVDAG
ADFIFTQMFYDVEMFIAWVRRVRKAGITVPIVPGIMPIQSYATFKKWVYRENISVPAHFT
EALEPVKDDDSAVRAVGTKLVAQMCRDILDADVGIKGLHIYTLNLAVGARMLLEEIGLVA
RVANTNPLPWTPSLTPARRQETIRPIFWANRQKSYLSRTENWDEFPNGRWGDSRSPAYGE
FDGYLLPQFKLSREEAIKLWGQPQTVQDVCELFAKFCMNELPSLPWSDSAASKETSIINR
QLAKMNELGFLTINSQPAVDGAKSDDKTHGWGPTNGYVYQKAYLEFFVSPSQLDALVHRI
ERDPHITYYAVNHQGDLRTNTHSEGPNAVTWGVFPGKEIIQPTIVEAISFIAWKDEAFSI
GKQWAGLYDDDSPTKSLLGEIMDTYYLVNVVHNAFKEPDAIFRPFFQNA
>A0A2D5YD72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MSDVLAKKHAIQAFMQETSVEVTPAGARAVKNFSTILKPKMTVYVTFLPGSDFRDTLETV
CRLKNEGYCPIPHFAARSIESEKIFEESLAKLRQEANVNEALLIGGGVDIPVGPFTASIE
ILRTGLFDKYGFNRIGVAGHPEGSPDITPKECEQAIREKNEFNQHTDADLYLATQFLFEA
KPLFQWEKTIRDQGXKLPIHVGIPGLATIQTLXRHAKQCGVGPSVRFLKKNPVDMLKMSL
RNTPFSSLVKAPSANPSKLIFDIVTGIASDKDCLIEKCHLYPLGGLQKSVDWLYQIQDGN
FSVSWDDFNVH
>A0A2M7BK99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium CG03_land_8_20_14_0_80_58_14|TrEMBL
MNDVSECIPALIRVKHNGSVSIVKNEKPFHDQLKSGDFIVTAEYLPKAETAGTAIEAALQ
ALAEVPSAVNVADNPFGVSMSSLAASVILARSGIEPICQVVTRDRNRIAIQSDLLGAAAL
GIRNILCLSGYHQTLTDNPESANVYDLDSTQLVGLVKKMRDQGELLNGERINGPFPVIAG
AGANPCLKPMDLGIIRLMQKVEAGADFIQTHAVFDVEGFRLWLEAAKQAGITGKAAILAG
VFPLESAEEAETLAKKYTEFQIPAPVIERLKSAGDREAQKKEGLAICVETIDKLKSMNGL
RGIHLLTGGKEETLPAILSASGWSVKR
>A0A0F7SIA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaffia rhodozyma|TrEMBL
MAPPPCPYVTSDGKPSYSFEFFPPLTQPGAQNLHDRIYRMSSLSPDGPALVSVTWGAGGS
TSDRSLELARFISSDLKNEKGNNVECLLHLTCTNMEKAKVIEALDFAKARGVKNILALRG
DPPRDAEYAPTQSLPVSQTNQPFEYALDLITFIRENYGDAFCIGVAGYPETHPDSPSTED
DIAFLKTKVDAGADFILTQLFYDVDVFLQWKTRCREAGITVPIIPGVMAIQNYSSFRRMT
TLCKAIVPQSILNDLEPIKHDDIQVKSYGVNLAISMCKRLAVEGHVEGIHLCTLNLEKSA
RRVLEGLGWIKPGADAKVVNGSGIKWPVPSQENAPLTANIPSITFQQAVTGTEQTTSTAQ
PQNELLGVIDGAGQIPEGESWDEFPNGRFTDPRSPAYGELDGYGAGLKILPNEALSHWGS
PSNTRAISELFTSYLRSEIPSIPWCTSPLESESRAILPLLLRLNSPEKGWWTVGSQPTLD
GTPSEDPIYGFGPRGGYIFQKSFVEFFVKESEVREIEEKAKDFKGVVTFYAGNKSGEFRT
NMSPEDVNVVTWAIFPGQEIVQSTIIEEVSFLSWKEEAFSIWQDWSCLYPAGSQPRKFLE
GIADEYWLVSLVHHDFKDPHGLESFLMG
>A0A2D5QF86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccus sp|TrEMBL
MDNHHLSFEFFPPKTKEGKIKLAEAHEKLNKLNPEFFSVTYGAGGSTKSSTKDIVIDIQN
KSSNAVPHLSICANDKPSLFDLLNEYKNAGIKKIVALRGDLPSGVGGTQQLVHANELVSL
IREHFSDNFEILVAAYPEIHPESVSYEKDIYWLKRKFDAGASRGITQYFYNSNSYIYFVE
QCRKFGIDAPIIPGIMPITNYYNLVRFSENCGADIPRWIQKRLHQYGDDLESLQDFGLDV
VTHLCEELLKNDAPGLHFYTMNQANVSLTLCARLGFSLANA
>A0A2M7BNW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium CG03_land_8_20_14_0_80_58_14|TrEMBL
MKTNSRVEKILAGGGFVVTSECGPPRGADAEVVRRKGELLRGVVDAVNVTDNQTAVVRMS
SLSACAILKGMGLEPILQMVCRDRNRIALQSDILGAAALGINNVLCLSGDHQKFGDHPQG
KNVYDIDSIQLIQTVCRMRDEGRFLGGEEIKGKPLMFVGAAANPFADPFEIRAARLGKKM
RAGCEFIQTQCIYNMERFSRWMEMVCERGFHEKCAVLAGVTPFKTAGMANYMKKNVPGMD
VPDEMIARMKGVPKEKQAEEGIKICVETIERLREIPGVRGIHIMAIEWETKVAEIVKAAG
LLPRPEIE
>A0A2I2DRR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium FS1-H7996/R|TrEMBL
MKVTDHIKKANGKTLFSFEVVPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVD
KGNGLLDKRITRLRPGTVGICASIMHKYKVDAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VVALRGDSRKDEPYFVPTKGGNAYASELVQQITNLNNGKYLHDEIEVEHNYDFCIGVAGY
PEKHMEAPSFNSDLKRLKEKVDAGADYVVTQMFFDNKKYFDFVERAREIGITVPIIPGIK
PLAIKRHLQILPQVFKIDLPEELIEAVEACKDNIAVRQVGIEFAIQQSKELKAAGVPFLH
YYSMGKSDNIKAIASELF
>A0A485NTI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lynx pardinus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEASSRTFSVPPSISRNPAMVNEPRGDGGPTSRSEGSS
SGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DGTGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCCQSREQITG
YLHKAKRLGLKNILALRGDRVGEQWEEEEGGFSYAADLVRHIRSEFGDYFDVCVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRW
>V7ZG88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. carotae str. M081|TrEMBL
MLHGPPSRSTSADMLEPPNRHQRTATPLMSPDTPSLASTLTDAYSLEVGANDMPALTAAA
PRILRGSTIAIPYLPSQNDDARLAAAQRVRTLGFAPMPHLSARRIASLDALHAFVGRAVD
EAGVERCLVIAGDAASAIGPFSDSVSLIDTGVFERSGITTIGLAGHPEGHPSMPATDQWD
VLERKCRSIAERGMAPLIVTQFAFDADIVLTWLEALRARGIAHPVRVGVPGPAGVAVLAR
YAARCGVGACASMLSKYGISIGKLFGSAGPDRFVDRLATGLTDAHGDVSLHFFPFGGIAE
SVAWVEQYRSRSAAHILSTSASRRSQ
>I6WSC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachnia propionica (strain F0230a)|TrEMBL
MSPTVAELLRDAASPTLSFEFFPPRTPEEQPRFEATVAKLGRFHPAFLSVTYGASGSTRD
RTVAATAALGSAQHATVVGHLTCVSQSTDDLLRTLDAFADAGVSDILAIRGDMPGGPQQP
WERHPDGLGNATELVRLIKAHGDFCVGVAAFPNVHQPDNDPELDARIVAEKAAAGADYAI
TQLFFESHRYVELVNRVRERGSQIPIIPGIAPLTVITQIERFASLADCPLPKDFVAALRA
ARNPAEVRSIGLSRAVNLCRELLAAGAPGLQFFTQNRWKATSEVLDAIGWGDRVS
>A0A2G9LNH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeum sp. CG12_big_fil_rev_8_21_14_0_65_33_22|TrEMBL
MSLLRENFSRKFTATGEVSPPPCPDKTLFAREVEEMKPLMGRILGVNVVEGPGGRVLMSS
LGASIYMIQHGVEPILQQVVRDKNRVALQNDLISASIFEIENVLSIAGDHPACPASDNPK
SKPVYDMDSTTLIVMLKKLNEGKLWNGKDTNYENKNLNAKTNFFIGTGLSPTSSPLDGEI
YKVKRKLIAGCDFFQTQGVFDIEPIINFLNLYEKTIGEKISDKILVGIVPIWSYGMMKYL
LTLPGIVIGEKFRNDVNEARKKQKETGQKGLIEEIGVNLCVDLVDKIKGLGVKGVHIMPV
GNLHAMKEILDKSGL
>A0A2G6GJN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNRDEFVARLLERPLLLDGAMGAWIHAKGIPNDISLGTVNVQNPAIVAEIHQEYIEAGAD
ILETNSFAANRLKLAEHGLQKETVAINQAAVDVARRVIAKFPHKPVLLAGSVGPLGATLA
PLGRVSVSQAREAFREQIEALLSAEAGGVDLLILETMSDFKELKTAVTVARDLSADIPII
AQMTFTRDDRTLLGLRPDEVARKLAELDIDVMGVNCSTGPANVLRIVSMMHQAVPERPLS
AAPNAGWPEQLEGGGVRYPATSAYFGEYARSFVDAGARIVGGCCGTRAEHIQAMRAALDN
PSAPKRPLPTIQIVPQEAAAETTAADKPTQMAQDLAAGKFIITVEMSPPHGIATERLLAG
ARMLKEAGATMLNLADSPLARMHMSAWAAAHLVQQEVGVETVLHFPTRGRNLLRIQGDLL
AAHAMGIRNLFVVMGDPTRIGDFPEAMDSYDIVPTGLIQLIKQQLNQGVDKAGRSIDQAT
SFTVGCAVSLTPKDPEREMRLLHKKIKNGADFALTQPVFDPAAAKQFIETYENSYEEPML
PLVTGIKPLYNSRNAEFLHHEVPGMVIPAEQRERMKQAKKQRREGVLIAQETLAQVKDFS
HGTYLIPAFGRFDLIADIIDSLN
>A0A1E4B8B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium SCN 70-22|TrEMBL
MTSRAELRQRLVDPDTVVVFDGAMGTMLYARGVFINQCYDELSLRAPDLVRGIHDEYVRA
GAEVLETNSFGANRFKLAHFGLAHEVGAINRAAARIAREAAGDSALVAGAVGPLGVRLEP
YGPTSFAEAREAFEEQVAALRDGGADCIILETFADLEEVTQAVRAARAVAPELPLIAQMT
VDVDGVTVFGATPEDVARALDALGADVVGLNCSVGPQIILEALEKMAAVTRRKLSAMPNA
GMPREVGGRKMYMASPEYMATYARHLLQAGAKVIGGCCGTTPAHIRAMVEGIRPLVPRLA
AARRTEAGGGDGTPATGSGSARAVGEREGVPRHVGVEPVPLAQRSRWGEKLATGTFVTSV
EIVPPRGVDASRMLDDVRTLATAGVDAVNVPDGPRAQSRMGAMMTSLLIEQQVGIETVCH
YACRDRNLLGMLSDLLGGAAMGLRNLLVITGDPPKMGPYPDATAVFDIDSIGLTNLVRSL
NHGLDPGGHPIGAPTRYVIGVGVNPAAIDPVLEGRRFAYKVEAGAEFAITQPVFDPRQLE
RFLRDVRETRIPIVAGIWPLVSLRNAEFLANEVPGVVIPDEILARMRRAHEQSADHALAE
GIAIAREMLALVRGEVQGVQVSAPFGKVALALDVIRG
>A0A536D342|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTKYTVTSTLRSAFFNRLAEGTPILFDGGMGTQLYAHGVPFHRCFDELNLLQPDLVQAIH
REYIAAGAEVIETNTFSANRVALAAYGLEKRVRDINFRGVKIAREAREVSGESVFLAGSV
SSIGQPLAPVGTIAPEEARAIFVEQIEALLEAGVDLLVLETFSSPMELREAVLAARSVSA
DLPIIAQVSVHEEGKTLAGASPAEVVALLDAMRVDALGVNCGVGPQTALDAVQQMRPLTR
TPLSAMPNAGHPTTQGGRQIYVSTPEYFADYARRFAEAGVSIIGGCCGTTPEHIAAMRAA
LPRNGAASVTVVESAERSQASVDETPSGLEAPRAETSSPLARKVRAGEQIISVEVDPPRG
INPNKMLQGAALLKEAGVDCVDVGDSPMARVRMSCIAFAALCEQRVGVETLIHFTTRDRN
LMALQSELLGAHALGIRNVIALTGDPPQMGGYPSATGVWDVKSPGFIRIIKQLNQGVDWA
GNSIGRPTNFLVACAVNPMADDLEYELDWYYQKVDAGADFAITQPLYNMEQLDRFFSRVP
HPPIPTVVEIMPLQSYRHAEFCHNELAGVVIPEEHLDRMKQAGERGIDVGFELAHRFLLD
VFDRVDGVLFVPSFHRYEMVAELVRETVRLRDRARVGVSAP
>A0A847F171|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sandaracinaceae bacterium|TrEMBL
MMLKDRMKPGARSYSFEFFPPRTDEAEEALFQLIAEELRPLDPSFVSVTYGAGGSTRDRT
LRIVARIVRETDLIPVAHLTTVLADEAELSRIIDELKSSGVRHILALRGDPPATLPEGKT
TIHDPNFQHARDLVELIHRRAPGHFSVGVAGHPEGHPESKGDLELDAKHLAEKVLAGADF
VVTQFFFEARHYFALRERAIRHGMPPDTPILPGIMPVTNFAQIKRFAELSGAEFPAWLEE
KLSVHADDPSALADLGIELATKLCEELLQGGAPGLHFYTLNKSPATRQIVANLDASQSRI
G
>A0A7C1PA08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGGSATSALPDGREQASFSRLHAVLLGGQFAVTAEIGPPRGATLAGIRRRARLLRGWIDA
ANITDGQSAVVRLASWAGCVALLEEGVEPVMQLQCRDRNRIALQADLLGAAAVGIPNVLL
LTGDHQRFGDHPDARGVFDLDSVQLIWTARTMRDHGRLLSGRTLSSAPRWFIGAVENPFA
APQRYRAERLGKKVAAGAQFVQTQFVFDVPAFARWMARVRELGLHERCFILAGVGPVRSL
RALEHMRREVPGLHVPEAVVRRMHAMPEDRVAEEGIALCAEIIQQVRDIPGVAGVHIMAF
GWEEAVPDILTRAGLGQRSQAGTAAVAAAELSHSPRSARGNAPEGEAAGRSPAPSPPSTG
GADGLASAPMSLAQYSRRLAWGAQAARLFRRGAGGAQTDRLDGYGR
>A0A7C0XY48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MERVLTEGHFAVTGELGPPKGTSADFVRRHAEALKNYVDAANVTDNQTAVVRMSSVAACT
IIKQVGLDPVMQMTCRDRNRIAMQSDILGAVALGIGNLLCLTGDHQKFGNHPEAKNVYDM
DSIQLLQMAKRMRDEDKFLSGDKVSGGVSMFLGAAANPFGDPFEFRPLRLAKKVRAGADF
IQTQGVFDIERFAQYMERVRDLGLHEQTYILAGIIPMKSAGMARYMRDYVAGLIVPDEMV
KRMEQAKDAKEEGVNIAVELIQQLREIEGVRGIHIMAVAWESIIPVIVERAGLYPRPIV
>A0A6J2TXC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila lebanonensis|TrEMBL
MLGVGACRILRVVSYQNPILMKQRHVGSAQLVERTQGVKRREWSTADSNVYALETNSSRN
SLKPYQVPDDPNYEPCVTFTPNQTERCQKPIGALLADLTAQSKFFYGIEIIPRLGGKPLP
IDFNDFLPVLPTFVSVVWLATQYWNIDPIEAVDTVQLVKHLEPRIPTLPHLTVYRMSEQR
LDDFLALNLKNLLAVRGDKVHESQPYKDSEQLVRRAQCVRGESLSIGVAGYPEGYTNEPH
GAENPLASVQFLKQKLAPNSLSCNSAIVPRKLSNSYSIAVLRILMCPS
>A0A7C1IRY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSKFFEVLARGPLLADGAMGTMLHARGVPFDTSFDELNLTQPATVAEVHRAYIEAGAGMI
ITNTFGANRYKLAQHGLAGKVREINAAAVTLARRVVDASFKEVLIAGDLGPLGVRLAPYG
RVKPEQAYAAYREQIEVLVENGVDVLVAETSADVHEIAEAIRAAKDVGRVPIIATMTFTR
DDRTLLGDPPARVAARLAELGADVLGVNCSGGPAQIQRIITWMKQAVPSARLAVKPNAGW
PEQVEGRIMYPAGPSYFGEYAVNFAELGVSVMGGCCGTTPAHISAMRAALDAPRPVGAHA
RSFAVAAEREEEAGERAASTQLAQKLQSQQFVFTVEMDPPKGVDTHKLLAGARLLAEAGA
DAIDVADSPMARMRMSAWAVAHLIHQEVKLETVLHFPTRGRNLLRVQGDLLAAHALGLRN
LFATMGDPTAIGDYPTANDQYDLVPSGLIKLITQGFNAGVDHAGNKIGTPTSFFVGCAVN
LIPADVDKEIKNLRKKLEAGAGFALTQPVYEVAPARAFLRRYEELHGPLNLPLIVGVLPL
YGVRHAMFLNNEVPGISIPEAMLKRMEQAGESGPQEGVRLAGELLTELMTVPHFRGAYLM
PPFGRFEMAAEIIEQAKVKS
>A0A6N6L0P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPLFSPRRYQPPFYPYSREKESLSMGLFTAFEAVTKGILFDCRMCGNCILQETALVCPMT
CPKGMRNGLCGGATPEACEVDPTRPCTWYVIYDKAEKKGQLDKLLEINAPMDGDRVGRET
WLEVIRVWRKRGGPKLLDYFRDRQKFDEEREGLFREIRQPDWWQGDAEYHAPQYEEPISQ
FEANLRTGAFTTVTEIAPPLTASTEIIGKKVGWLKGYVAAANFTDNASASPRMSSIASSK
ICMGHGIEPIMQIQARDRNRTVIESDVMGAAGLGIRNILCITGDHQRFGPGPLSKPDQFD
MDAVQMLWMLRRMRDEDIYLDGRTIKIPPRFFLGAAASPFGAPPKYEAIRAEKKINAGAQ
FIQTQPIFDYDRFTDWLEALDKRNLLNKVYLLPGLIPLKSARATHFMDEEVPGVVIPPEL
IKRMDEAGDKEGQQQEGVTIALELIEKLKNTPGINGLHVMAVHWEAIVPRLIEEAGLPRP
LEQPLPETEPASSQV
>A0A5Q2TP23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gracilibacillus salitolerans|TrEMBL
MSDLITHLQNRLIVADGAMGTLLYSHGVDRCFESYNTTHPDEILHVHQTYLDAGAEVIQT
NTYGANYIKLSRFGLEDQVHQLNTKAVQLAKTAAEDRAFVLGTIGGIRGVQKLITSKKEI
IRSFKEQLFSLLLEGVDGILLETYYDFEEIKQVLEIARQETDLPIIANVSMHEPGVMENG
IQLAVALQKLEEIGADVVGVNCHLGPHYMIKALESVPLLEKALLAAYPNASLPAYQNGKL
VYNQYSHYFERCAKDFRDQGVRLLGGCCGTTPEHIRALKEGIADLEPIKEKEIKQVTFTQ
NTNDQQPPLRTTLADKARKRHTVIVELDAPKHLDTESFMNGAFALENAGVDAITLADNSL
ATPRISNLAMAMKMKQAGCHATPLIHLTCRDRNLIGLQSHLMGLHTLGFHEILAITGDPT
RIGGFPGASSVFDVTSFELTKLIKQQSNQGLSFSGRSLKTNTQFQVAAAFNPNVANLDKA
VKRMERKIKHGADYFLTQPIFNHEQIIELHRLTKHIDKPIFIGIMPLTSHRNAEFLHHEV
PGMKLSDEVRTRMQHHDNRQDSLQEGIQISKELIKTAMNYFNGIYIITPFMHYPLTVELT
KYVHQQAKLVTKI
>A0A7C4C0U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MADQRASNGYVSGSNLERVLKSGNFAVTAELGPPQSADAEVIRKKAALLRGYCDAVNITD
NQTAIVRMSSIGAGAILVSEGLEPVIQMTCRDRNRLAIQSDLLGSYALGMRNILCLTGDH
QTFGNHPQAKNVFDIDSIQLIQIVKNLRDEHVFQCGDPLKGLEPRFFIGAAESPFAHPIE
FRPYRLGKKIKAGANFIQTQLVFDIPAFEAFMEKVRALGLHQQAYILAGVGPLKSPAMAK
YMKESVPGILIPPELIQRLEDAGLPWAGKSKDELTKEEKKARSEAWKQTGIDICIELIQK
IMQIEGVAGVHIMAIEWEEAVEPIVKGAGLYPRPVVEPLIA
>A0A3D1U1G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQHPFRLRLHDQKPIVADGAMGTQLYALGVPFDHCFDAQNLDRPELVEQIHLDYLRAGAE
LIETNTFGANRFKLTAFGMEDQVREINRRGVRVARGAREIVGRTAFVGGSIGPTGRTLEP
YGNTTAAEIFTVFQEQVSALLEGGVDLLIFETFSDLQEIAEGIRAARELTDLPIIAQMTF
TEDVRTPQGHSARQAVEALSSLKVEVIGTNCSVGSSTSLQVVEELLAAGASTVSAMPNAG
WPTRVGNRVIYLSSPEYMAEYGQRMVEAGVRIVGGCCGTTPRHIRALSAALQAPLGAAPR
VELTPAVDTEVEVNGHEDISSIAPKLGSRRVISVEIRPPRGSNPAKALEGARLLRDAGVD
AVNVLDSAMSRVRMSAVATAALIKQQVGIETILHFTTRDRNLMAIQSDLIGAHAMGIRTV
LALTGDPPSIGDYAQSKAVYDVDSIGLIRIVKKLNSGHDIGGNSIGTPTRFLVGCALNPT
AEDLDWELSRFEEKLEAGADFVMTQPVYDAGLFRDVLKRIGTMNVPILMGILPLQSHKHS
LFLHNELPGVRLTEAVLDRMERAGADGLQEGLRISQEMIEECGDLVAGLYVMPSFGRYEN
AAHLVSRLVASS
>A0A6L7Q0F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MMMKVTDRSSATTGRPAFICDYSPPRSGRPEHTPEPPAEADFVSAAYNPGRAVRVNSVAM
AAALRHRYAANPIFTLATRDMNRLALESLLLGAQALELENVIVVAGDPFGSQDAAATVND
YRATELIAAIARLNSGIDYRGRGLRAPTDFCIGATVDLGRGLEEEAQLAVRKVQAGAHFL
ITQPVYDPAAVRRFNDACGGLTVPVFYGVGLMEPDGVSFAAVPDWADDALAAGRSGVDIA
LEVWTNLQAAGATDCYLVPPIRRNGARNYQAAREFLQRAANG
>A0A839BPH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. RHBSTW-00318|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPHWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGA
>A0A6J4NDN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Nocardioides sp|TrEMBL
MTTDRGQSLRDIIEQGGRSFSFEFFPPKDAAGEQQLWQAITELEPYCPTFVSVTYGAGGA
TRDRTVAITERIARETTLLPVAHLTCVGHTTDELVGILQELADAGVHHVMALRGDPPEGP
GSPWTPTEGGVTYASDLVRLIKRTADVRVGVAAFPEGHVEAASLDDDARVLRAKYDAGAE
FAVTEMVLRASDYEGLVERAAAAGADLPILPGLMPILNLRSMTRMVELSRRDLPREVVAR
LAPYEHDPAGLRAEGIQIATELGEALLAAGAPGLHFYTLNRSQATREIYANLQIAV
>A0A6N8YV20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVKVTDRVQASTGLPVIICDYSPPRSGLLSDVSPPPTGADFLLVNANPGRSVRADSAMLA
AVLKQQTGQEVIFALLTRDMNRLALQSHLLGAQLLGLENVVVAGGDRFHQNEPSAVSAVA
DFRPTELIASVTGMNQGRDFRGRNLASPTNFCVGATVDLARDSATECKLAARKVASGAEF
FITQPLFSVHSKERFEGSYLKTTGDGCPVPIFWGLQLLEKGSVSFAPVPARFQSELESGR
SGVDIALEVFHKLHGSGVSHVYLLPPIRPGGQRNYEVAQEFVEAIGK
>A0A7C3K140|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MHQRLASGDFAITAEVVPPRGATLSGIRRIATHLRDWIDAANITDGQGAVTRMSSWAGSL
GLMQADVEPVMQFSCRDRNRIALQADLLGAYAVGIPNVLCLTGDHPRFGDQPDAKPVFDM
DSVQLVWTARTLREEKRLLSGQQLSVAPRWFIGAVENPSAAPQRFRAERVGKKIAAGAQF
IQTQFVFDVPIVERWMRQVRDLGLDKRCWFLCGVGPIRNRRVLQFLQALPGVYIPDHVVK
RMLGVPEDQMANEALELCSETIQQLREIPGVSGVHVIASGWDDFIPEVLTRAGIGRRKPL
DPAFEDAAAAVARPAGPGAARVSGGQPGAD
>A0A3A0BRU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPGFTPGKRYQPPFMPFKRQPFKKRALATIELAVKGPLFGCRMCGNCLLQETALICPMEC
PKGLRNGPCGGSTPERCYVDESRPCIWYKIYERSFQLGREARLLEVLPPMDWEKAGTDSW
GGIFDRVKRLGIRNLFSHLTSGEPGSVSQTLDSIFRPVRQPDWWQGDAKYHAPAYAEPVS
ELERRLKAGEFVFAAEIAPPLSINTDKLRRNIAALKEHAAALNFTDNASSVPRMSSLACS
AISLELGAEPVMQISARDKTRVGLQSEVIGASALGIRNMLCLTGDSMALAPGPKGRMDIV
DIDSVQMLWMLRRMRDEGRYLDGREIKTPPKYFLGAAASPFASNMKFQALREQKKVNAGA
QFFQTNAVFDADALDEWLNELVKRDVLDKVYILIGISPLKSYRVARYMNDKVPGIFIPAA
VMKRMELAEEKGNAEEEGVQIALELIEKTRGKQGVNGIHLMAVGWEEVVPRIIEEAGAAK
SSKLRALKGGIPLGIIQPDE
>A0A7S9L374|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter endophyticus|TrEMBL
MKITEHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADNAFVPTKGGHCYATDLIQHIKNHNNGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNADFKFLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPDELTDALSYAKNNAEAREIGTQAMIKQCKELIDFGVPVLHF
YTMGKPEQTKQIARAIF
>A0A6N8Z5H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPGKASPRSRKSASPNFEPNDTTPGDGLKIKKILNERRTISFEFFPPREADGVPAVIDVI
KGLQQFSPDFVSVTYGAGGGTRAFTEEITMRIRAETDLEVMAHLTCVAQTRGEVHGVLER
LQGAGIENVIALRGDRPADSNETAPGVDEFPHATDLITHITDNFDFGIAGACYPEGHTES
ADLDTDIEYSRMKQDLGADFLITQLFYDNDYFYRFQERAAAAGITVPVIPGVLPILSTPQ
IRRFTSLCGATIPAELDERLERFSDDNRAVREIGVEHATRQAEDLWANGVPGIHFYVLNR
RYSVSHILRDLNIAGHTGE
>A0A351G285|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAANRFLKLLSSSTNPIVFDGAMGTMLHTRGESFEGCLDELNLSNPGLVAEIHRAYIEAG
AQVIMTNTFGANHFKLSEHGLENQLHDIICAGANLAQKVVEASFKPVLIAGDVGPLGIRL
APFGRVTPEQARQVFAEQIKALADCDVDLIVIETISDLYEMREAVLAARQVCDLPVLASI
TFTRDDRTLLGDHPKKAAEWLHAAGADLIGVNCSEGPAQVLRIMRQMRQALPDGRFSVMP
NAGWPERVGGRIMYPAGPEYFGDYAVAFRQAGVDVIGGCCGTTPEHIKAMRTALETTLPE
EPAELPALHEQSSSPAAAAEQEPSHLARQFLNANFALCVEMDPPRGLSIHKLLAGASLLQ
EAGADVINVADSPMARMRMSPWAVCELLQNQVGIETTLHFPTRGRNLLRVQGDLLAAHAI
GVRNIFVVMGDPTEIGDYPEAMDNYDLAPSGLVKLIKQGFNTGVDHAGLEIGEPTNFYVG
SALNLTPKDIEREVKVLRRKLSNGADFFLTQPVYEPEKALRFLKRYAEEYGDFDHPILVG
VLPLYNLRHTNFLHHEVPGIQIPDWIQERIRKAGDDSAREGIRIAVEQIEQIKEWGQGIY
LMPPFNRFEIAAEIIEQVKS
>A0A7C0TVB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSRLADAIVAGEFVVTAELGPPKGTDVAHLLEMAELMRDHVDAINVTDQQSSVMMLGSLT
VCHLLHQRGIEPVFQVTCRDRNRIALQSDLLSAAVLGVENVLCLTGDYVTLGDHPDAKPV
FDLDSVTLLQAVAALQEGHDLAGKPLQGTPTFFPGAVVSPVARPLGPQIAKMEKKVLAGA
RFFQTQAVYDPAAFESFIRQVEYLQVPILVGIILLKSAGMARFMNRNVAGVTVPDALIEE
IGRVPPPERPAKSVEIGARLIREMKDMCQGVHIMTLGWEKYVPQLLDQADVERNRRTD
>A0A536G2W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAGLVDRLRGRVAGGLAEAEREALRGVLADPIFELLPLKSIADQIPALPPGARVSVTASP
AKGIDATLDWAARLQADGFRAIPHLSARMIASRAALAGLLDRARAAGLTHAFVVGGDADE
PGAYLDGLSLLQAMAELGHPFTTLGCPGYPQGHPDIPDAALAQALRDKAPYVDHVTTQMD
FSADAVARWVRARRAEGLGPDVVIGVPGVADPQKLLSIAARIGVKDAKRFLLKNVRFVTG
LAKSGGFYKPTSFVEALGPLVADPTARVTGLHLYTFNAVEATEAWRQSMLNGLRPA
>A0A4Y9QZF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus kandeliae|TrEMBL
MKITEHLKNAKSTLFSFEILPPLKGQSLKDLLEGIEPLMEFKPPFVDVTYHREEYIYKKH
PNGLLEKISTKKRPGTVGICAAIMNRFHVDAVPHLLCGGFTKEETENALIDLNFIGVDNV
LALRGDAPKTEGKFVPERDGHHYASELVEQIVRMNQGKYLHEETETNFHTDFCVGVAGYP
EKHFEAPSMKFDLKYLKEKVDRGAEYIVTQMFFDNQKFFDFVKKVREIGIEVPIIPGIKP
ITTVNQITMLPRTFYLDLPDALMDELEKCKTNAEVKEVGIEWAIEQSKELIAAGVPSLHF
YTMSKADATYKIAKAVF
>A0A359HH23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MDFAPHARRRQIXAPFASEPKFQAIREHKKVNAGAQFFQTNLVYDADGMEIWLNELAKRD
ILDKVYILIGITPIKNYKIACYMNDTVPGVFIPDKLMKRMEAAEEKGNAAEEGVQIALEL
IAAIKGKQGVNGIHLMAVGWEEIVPRLITEAGLLPPDFVAPDETEKPTKVKVIA
>S2KDC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas anticariensis (strain DSM 16096 / CECT 5854 / LMG 22089 / FP35)|TrEMBL
MSLQEHSLDISFEFFPPSTDAGREKLMGVRDALAERKPRFFSVTYGAGGSTQARTTQTVK
AVRECGIETAPHLSCIGSDKGELRELLAQYRNDEISSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAGYPESHPQAPSFEKDLENFARKVKAGANLAITQYFFNAEAYF
HFVDRVRHLGVEVPVVPGIMPITNYTKLARFSDACGADIPRWMRKQLEAYGDDSESIRAF
GEEVVSRLCQQLIEGGAPGLHFYTLNQAEATLKVLDNLS
>G0CK82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. raphani 756C|TrEMBL
MMSPDPPSRAATITDAYSLEVGAHDVAALTAAAPQIMRGSSMFIPYLPSQNDDARLAAAQ
RVRALGFAPMPHLSARRIASRDALQAFIGRAVEDAGVERCLVIAGDVPSAVGPFSDSVSL
IETGVFERSGIKAIGVAGHPEGHLGMPASAQWDVLERKCRSIAERGMAPLIVTQFAFDAD
TVLTWLEALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACTSMLSKYGISLGKLFGT
AGPDRFVDRLTAGLSEVHGNVSLHFYPFGGIAQSVAWVEQYRHRSARPLAD
>A0A3B6XZ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas piscicida|TrEMBL
MALTLQEKIIDPNQGVYLIGTTPPKIGTDPEQLKSIAAKLLGRLHEIEYDGVIIYDIQDE
SSRTQVPRPFPFKHTVDPCEYSQLIRELSHLDVITYKSVAQRDSEAFGNWLSSTKQQYGL
NNLVLVGSPSSQGDIKLPLSEAYKVLKHHQDDFFLGGVTIAERHASKRNEHERLIDKTEQ
GCQFFVSQAVYDAQATIDLITSYARTCKQQGQTPKRIILTFTPCGGEKTLQFMEWLGISV
PEATKWRMLDADNTLSESIRICRENLDQILKSCSHLDISLGLNIESLTNRKEEIDASINL
YRLLKATMELCLAEKQIA
>A0A0A5HYR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium sp. (strain ATCC 43367)|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDANREELIQIADDYWNNGIQSIVALRGD
IPPGGGKPDMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPSAS
>A0A536MMQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLARSKPSVSFEFMAPRDESEVETLERTIAALAGHAPDWVSVTYRVRTGEKTLEL
VTRIKRHYHIEAMAHLTCANTADRTRQILNWMEREGVANVLALRGDAPTAGEPFIPADPQ
LAHGSDLIALVRRSGYRFGIGAACSTEKHPESPDVEHEFRYMRLKVESGADFLITQLFFD
NKHYFDLVARAREAGIKVPIVPGLMPVPSRRSLAVMTAMSGATVPAGLQAAIDAAPDDDA
IRAVGVRHCISQCAELLEARAPGLHFYTFNRARAPMEILAALRGQQLLAS
>A0A2E4JLV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTTLVELVAKKNRRPFIVCDVSPPRGGSTQLLSSITNVTPDMFFVAANPGGTVRASSLSV
AQWLESNTKIPALFTMTTRDMNKTAMQTTLLGAHVMGLRNLVVAKGDEFPVSGRWTDVSV
KGFTPTAFIRSVKEMNKRTDFTGQALSEPTDFCIGSTLDISRDWGSEXSLTGNKVRXGSD
FLIAQPNFDPVLAGKFLEEYQNDQGADLTVPVMWGVQIMSKDSISFTHVPDQVTKELALG
NSGYEIALEMIHKYLEIGIKDFYLVPPIFRGGRRDYESAQAVIEDL
>A0A535TXD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLRDGRFVVTAELTSTNSADPEATWRLAEVLRGSVDAVNCTDNTGAHVHMSSLAAAHLLV
EKGIEPIMQLTVRDRNRLALQADLLGAAALGVRNIVLMSGDDVTAGDHPEARRIYDIDSM
QLIEVAAGMRDRGVYLSGRKLEQSPSFFIG
>A0A535D1T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRLDTVLQERRPIFSFEFFPPRSDDGVRSLFETIAHLRELEPTFVSVTYGAGGSTRTRTL
ELVTRIRRELDIEPVAHFTCVGASVGELRANLDAMRDAGIDNILALRGDPPDGEAQFIAA
EGGLSHGSELMQLITSGYDACVGGACYPEGHLETPDIEDELRYTRLKVESGASYLITQLF
FDNRAYFDFVARARADGVTVPLIPGIMPVTNVDQIKRFTSKIGATIPAPLLDALTARKDD
PDAVLQLGVAWSTLQCAELLSAGAPGIHFYTLNRSPATRAILSALLAARPWERRL
>A0A4R1NXG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shimia isoporae|TrEMBL
MTTPQVSFEFFPPQNLEASFRLWDTVQALAPLDPKFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNASKTETLQIARGFAASGVSELVALRGDPPKGANRFEPHPDGFANSV
ELIEALSATGDFTIRVGAYPEKHPEASDMKADIDWLKRKIDAGAAEALTQFFFEADSFLR
FRDACADAGIDAPIVPGILPIENWKGARNFAKRCGTTVPTWLEDAFEKATRDNREDLLAT
AVCTELCSDLLEEGVEALHFYTLNRPELTRDVCHALGVTPQVRLENVA
>A0A2E9N5P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVAFHLYGQRTSPTEKLHRRNKSAGGDWIPGLKIKDILTKTRPISFEFFPPRNAEGIPAV
LETMDELKPYCPDFVSVTYGAGGSTRAFTEEITLQIKRETGVEVMAHLTCVGQNKEEIHE
VLQRLESEGVENIIALRGDPPRGSTEFVPVEGGFQHATDLLKHVQSNFRFGVAAACYPEG
HTESVDLDTDLDYIKMKVDNGADFLVTQLFYDNRHYFDFLERAHAGGIDVPIIPGVLPVL
NSAQVRRFTALSGSEIPPDLDKLLDKYADSDNSARDMGVEYATAQVRELWDAGVPGVHFY
VLNRSYSVSRILDNLTISGHQRQD
>A0A535ZPV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGCARTAIAKFFRTRAASGSRPGKGRDGCPSSRITSSICRNRWTGSCRAPPRGSTSSTAV
TRSRPGAGRAVATVSRLASLLRDGRFVVTAELSSSNSADPDATWRRAEVLRGSVDAINCT
DNTGAHVHMSSLAASHLLVEKGLEPVMQLTVRDRNRLALQADLLGAAALGIHNILLMSGD
DVTAGDHPEARRIYDIDSMQLVEVAAAMRDRGTYLSGRKLEQAPAFFIGAVENPFAPPLE
FRPLRLQKKVQAGADFIQTQLVFDVPLFARFMAMAVDLGLPDKVFIIPSIGIPRSARGAH
FMREKVPGLHVPDALVARLEKTPPGRQAEEGIQIAVELVNAVREIPGVAGVHLIGIKWEE
GVVQVADAAGLLPRPTLSPIATVGGSR
>A0A2E6ZM07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNNILEAINRKINKPFVLCDFSPPKGGNPDLLADANELTPDMFMVAYAPGNSVRVNPIFV
AEWIQNKTKVPSMFAISTRDENKRAIQSLLLGAELKDLRNLLVVAGDKSVDGHLSMQVDM
KYSGPTELIASIKAMNDRRDYQGKPLIYPTRFCVGAALDLSRGWENEVRLTKAKVDQGCD
FMISQPVFDINLPHKFLSFYKDSIGENLNVPIMWGIQMVEKNTVSFAAVPEWLYQELENG
RLAHEITIDLIRQYREIGIETFYLIPTVFKGGRRDYVSAQAVIEEVG
>A0A1D2SVS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. SCN 65-20|TrEMBL
MTPPRPRHPDENPHGIDLPLEPQPGHSSRGRLERVLRRGEFAVTTELNPPDSANPEDVYD
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVF
ILCGVGPLASAKTAKWIRSNVPGIHIPDSVITRLEGAQDQKKEGKQICIDIINEVKEIAG
VSGVHVMAYRQEEYVAEIVDESGVLKGRRPWKRESRRDDQLVADRLDHLLHDDVTESQVD
MVKTAH
>A0A536DLM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MIAGPPVKPSRLRLDFASREALRRFLSHPRYEVLPTEESGDLVMRNLPTEVTITVTSSPR
RGIEATLALAERLAGGGYAVVPHLAARLVRDEPHLKEILARLDAIGGRVFVVAGDSQEAA
GAFPDSVSLLEAIASHAPAMKEIGVTGYPERHGFIDDDLTIQAMWDKRRQATYIVSNLCF
DVRVVKKWIARVRKRGVPLPIFIGMAGVADPAKLLRVSTRIGIADSARFLRGHTNWLMRL
IQPGGYAPDRFATGLMPELARPDMKVAGIHVFTFNEIEPTEQWRQQMLARLS
>A0A0U5F211|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter ghanensis|TrEMBL
MSLNRLCVELIPRSAESLAEDVETVKTVFPVADTLNVPDLMRFPLRSWEAAAQLHPTFPR
VIPHIRAIDIAPHAPLPGAEQPGLEEILVVHGDPPADLSMRTYPNSTESIIRRYRKEAPH
LRVYAAFDPYRRAPWKELEDIARKKEAGASGFFTQPVFDYKLFDLCREWLQGEDVFWGLS
PVIGPRSRSYWETTNHIVFPKDFSTTLESNIAFAQTVLRELNQDKGSAYLMPVRVKLEHY
LPALLEAVS
>A0A174JH59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDNKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A2E7G4M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLKVTELHKEKGTNPIFIVDFSPPKSANINFLDESKKLNADYISVSYNPAKSIKVFSMIV
AQEVKQISNKNVIFSLATRDMNKLSTQSILKGAQLLGLDNLIVFKGDKVTKKDIFKEVDD
YTPTSLIKDIIKMNEGKDLNNHKIQPPSNFCVGAAINTSSNSNKEIKLTKNKLDSGAHFL
ISQPSSDPDNFLRFHSKYIKEFKKKINIPIFHGILMINKDSLYYDNISKSLSEKYNPKDS
DGTIHTLKIIESFLEKGINSFYLIPPIYKNGLRDYKLANFVIDKIKNN
>A0A535VWZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MIAAKPSRLRLDTASRAALLGFLERPRYEVLPTEEAQDLVARNLPTEVTVTITSSPRRGI
EATLSLAEKLAETGYSVVPHLAARLVRDAAHLQEIRSRLSAIGGRVFVVAGDSQEAAGEF
PDSVSLLEAIAAGSPAMNEIGVTGYPERHSFIDDDLTIQAMWDKRRLATYIVSNLCFDVR
VVKRWVARVRKRGVKLPVYIGMAGVADPAKLLRVSTRIGLSDSARFLRGHSNWLLRMIQP
GGYAPDRFATGLMPELARPDLKVAGIHVFTFNEVEPTEAWRRQMLSRLRQQG
>A0A428U486|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium ambrosium|TrEMBL
MVSNSNCPLANCCHAAVLPPPPHPRILQLPESNKLQSADTFAVPSSPGPAYSTEPQLLPF
TTLSSIHQSLRKPPSPCISRRCSPTLRGAANPPSPSSTSPPKTAQGVQNLYDRMDRMYNL
GPKFIDITWGAGGRIAELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGC
TNILALRGDPPRDQDKWTAADGGFQYARDLVKHIRSTYGNHFDIGVAGYPEGCDDNKNED
ELLDHLKEKVDMGATFIVTQMFYDADNFIRWVKKVRERGVNVPILPGIMPIATYASFLRR
ANHMKAKVPQAWLDALEPVKNDDVAVRDIGKSLVAEMCHKLLANGIHHLHFYTMNLAQAT
RMVLEELNWAPSAERPLQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPN
GRWGDSRSPAFGELDAYGIGLTGTNEANRKKWGEPKTVQDIAQLFVRYLRNEIDSLPWSE
SPLTSEADEIRDDLVELNKRGLLTVNSQPAVNGVKSSHPVHGWGPSNGYVYQKSYLELLV
HPDVFNDMIGRIEGHPDLTFYAVTKDGELRSNAPSDCPNAVTWGVFPGKEIVQPTIVESI
SFLAWKDEAFRLGVDWAHCYDASSPSRALIDEVMNEWYLVNIVNNDFHQNATIFELLKGL
EVKDLTTPATPKSEPEANGTEPLANGAAAA
>A0A535XYR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARIVDLLATGQTFSFEFFPPKDNEEQQLLTRTIADLQPLKPSFVSGRPSDARRRLQDRR
HRDRHARGGRG
>A0A535H8H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSRITDLLAAGQTFSFEFFPPKDSEEQRLLTRTIADLQPLRPSFVSVTYRGGRISRERTT
RVVVDLLRTTDLTPMPHLTCVAHPRFELGEIIGGFRAAGMENLLALGGDPLPAEESYKEL
AYASELVELGRRLGFQSIGVAAHPAGHPRSPDLTSDRRYLAAKMRLADFAITQFFFKVEE
YERLRDEMAALGVNKPIIAGIMPITSLTSVQRMAQLSGYAVPDDVVQLIEAGGTDRDEIR
KRGISVATNLCRDLLEAGVPGLHFYTLNFSKATREIYTNLGLAVT
>A0A535HPW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIDRMLRERGPVFSFEFFPPHTDEGEENLFRAITELRELEPSFVSVTQRRGSTRVRTLE
LVVRIRRELGLEPMAHFTCADATVDELHGVLGRLRDEGIDNVLALRGDPPSADGAFVAAA
GGLSHSSELLALITANYDFCVGGACYPESHSESVSPDDDLRQTKLKVDSGACFLITQLFF
DNRAYFDFVARARRAGIDVPIIPGIMPITRATQVDRFESKMFGAHIPEPLCEAVQRRKEE
PEAVMQLGVAWSTLQCAELLAGGAPGVHFYTLNRSPATRAILSALQAAQPWERAG
>A0A0U2XE80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus rotai|TrEMBL
MRTDTLFNEKTVFSYEIFPPRRTAPVDTIYHTLARLKGQQPDFISVTLGAGGANANLSTA
DIAQKIQDEQFLPSVAHLPAVNFSKDEIVVILEELKQKKVENILALRGDLLPDKEPKKDF
AYANDLVLFIQEQGDFNIIGACYPETHSEAANSVEDIRNLKRKVESGTNQLISQLFFDNN
YFYTFKEKCDIAAIDVPIQAGIMPVVNKKQIERMVKMSNVTLPTKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVAQGVDGIHLYTMNNPYVAQKIREATRSLFEA
>A0A2E6GG51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MDQPEKNLKNKSQKIRFICDFSPPKGSDPNLIKQAEQLSTDYISIAYNPGKSVGANSAFT
AYLIKKKFKKNVIFTLATRDMNTLAIQSYLVGANLLGLNNVIVLRGDPLNQKEKDIMSEI
HDISTTETISSIKNLNSGKDFKNKSLKSKTDFRVGATVDLWKNFENEKKLTRSKIESGVD
FLIFQPIFNPNLLIEFLTLYRKSYGEEIKVPLFIGLQMLEQNSLCFSKIPQWISNDLSNG
RNGISISEEILENFISEGFTSIYLVPAIFKDGKRNYKTAKCILDKYNF
>A0A7V7I328|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. BB51/4|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGILISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1M6T8X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. (strain UWH6)|TrEMBL
MKIVDILKQDKMSLSFEVFPPKKETSFESVKNATESIAALGPAFMSVTYGAGGGVSQYTL
EIAKNLKSKFGVPMLAHLTCVSSSKETVKQRIEDMKAAGITNVMALRGDLTPELIANGRT
DCDYHHAVELVRELKDSGADFCIGAACYPEKHPESANQREDIKYLKEKVDAGADFLTTQM
IFDNNLFFNFLYKLREAGVTCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGIMRNVSAILGKNFIA
>A0A432QL42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp|TrEMBL
MKSGSNLERVLKSGEFAVTGELGPPKNSDPEVVRKKARILKGNVDAVNITDCQTAIVRMS
SIGAGLIAQSEGVEPVIQMTCRDRNRISMQSDLLAASAMGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQMLGMVRDMRDAKKFQCGEEIKGSAPELFLGAAANPFAYPFEFRAVRMGKK
ISNGADFIQTQIIYNVEKFARFMEMARELGLPEKAYILAGVTPPKSLGMARYMKKFVPGM
DVTDEVIDRMKGAKDKKQEGINICVDIINQVKEIKGVAGVHVMAIEWEEAVAEICESAGL
LPRPTFDEVASSTVELTPSVASDQAVEIRSQDAVTDDVMNKAREEAASIVAAARLEAETI
LSGAKPVTTTTETAAIATDDAGEHEMNEKERQMALESVNQGLKALKSAYGLSDDQFEALL
NFASAEAVLKRDPAIGAHPSSAPVATAAAPVPAAAAKPAVDDAAKKAEEAAAAKAKAETA
AQAESEARAKAEAEAKAKKEAEAKADDAAAQKVKAEAAAKAEAQAKAKAKAEAEAKAKKE
AEAAKQSKPAPVAKAVKAAPAAGLAASVLSVEGTPFAERTTKVPASAYKVDYSGSIREVT
LGNGENSITVGGSNSMPFHLFEGDMQHKPLIAMEIQDIRPDNWPETLSQYFDDVMDSPVD
WAKKCVEEYNADALNIWLIGTDPNGENRPSADAAKDAAAVIEAVDVPIIIWGCGNSEKDT
DTLREVTSIIGDKKVCLAPLEDANYRAIGATAMAFQHPMVAASPIDVNLAKQLNILLENL
GVPLDSVLMDPSIGALGYGIEYTYSVMERIRIAALTQKDEKLQVPIICNLGREVWKTKEV
GLPSEELMGDQEQRGIMMEAMTASCMLMAGGEVLIMRHPKAINMTKSLINGLIA
>A0A014EBN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_2|TrEMBL
MKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGKARDIQDFEQFLEQA
QTANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGVRIGGAFYPFKYVE
AERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKAFLTKNNYSQQILACVMPLTLGRA
NFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKHLGFAGIHLSACHKP
EEQMLLESYIEQYRHLELNVLEELWNSLWQVTTGKEFSPEIVRFSRQPTSKQLIKYRQLH
VMHEAMFGSKIAKGVGRFIFKASFWENALIAKLLLKTEVLSKHSLVGCESCGQCRLGDTL
YICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVEQTEILKDKLIPTVSIE
TRGTSSWKNWYLGAEA
>A0A1F8LZK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_50_10|TrEMBL
MSLREKLQSGKFVVTAEIGPAKGVDIHEFNENADLLKSRVDAVNCTDQQSAVMRLGSLAA
CYLLKQKGVEPVFQMTCRDRNRIALQSDLLSAYVMGVENVLCLTGDYVTLGDHPDAKPVF
DLDSVSLLYAARQLEQGKDLAGKELKGTPKFFLGACVTPGADPVEPQLIKMERKVKAGAQ
FFQTQAIYEPKTFEAFMKEAKKFGVPVLVGIVVLRSAGMAKFMNKNVAGIHVPDELINEM
DKAENKLEKGIEIAARLINETKGMCQGAHIMAIGLESKVPAILDAAKL
>A0A7V3EFL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MRRSIEDLLKKQPIIFDGAMGTELYNRNHFINVCFEELCVSKPAVVRTIHEENKNAGADV
ITTNSFGANRYKLAEYLLADRVRSIAKSAAELARSVAGEESFVAGSVGPLGKIVGKEIDE
RDAREAFLEPILGLQEGGVDFIIFETFSRSKELKAAALAASEVGIPYIGSLAFGERNISR
AGEGIEEFFAPILELPHPPFMISFNCSVGPKQMLEYLEDFLPHAPLPVLIMPNAGYPQLV
HDRMIYMTTPEYFATYAKRFAELGAAAVGGCCGTTPAHIAETARSVKAFFRHRIDIPSSP
ATVTLRTPPPRESRSALGAKLEAGAWVTSVELTPPLGYDLSGILAKARSCKEAGVDAINI
PDGPRASSRVNPMVTALRIQQDAGIETVLHVTCRDKNIIGLQSDLLGCAAAGIKNLLLIT
GDPPKLGDYPQATAVFDLDSIGLTRIASRLNQGVDIGGKEVNPPTAFLIGVGADPTHLDQ
ERELDRLAKKVEAGADFCITQPVYDVEALLAFLERIRPLRLKVIAGVWPLASLQNARFLN
NEVPGVRIPESLMKRMEKAGSKEEARATGIAIAREIIQAIRPYVAGVQVSAPFGNVDTAL
KVLSIGS
>A0A2S5HZI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus laterosporus|TrEMBL
MGKRDLRAYLTEHLLVGDGAMATQLYEQGVPIGVSYEELCLSNPQIIRNVHAAYYEAGAR
LIETNTFGANRDSLSRYGLENKVTRMNRAAVTIAREAVGDDAFVVGAMGSIIAGRVRDKQ
IDQFKDQFEEQATSLLHAGVDGILLETFLDVDELLLALEVMRPLTELPIIAQLATLEVGT
TRDGHSLTQAFQLIKEAGADVIGLNCRLGPAEILRSFEATVCPNDVYLSAFPNAGRLGLA
DGTLSYKSSPDYFAESALRLHEQGVRLIGGCCGTTPEHTRAIAEKLARCVPVPRVNPPVS
VHSETIEVQAVQKRLEPSIIEEVKHHPTIIVEFDPPKDLHTEDFLQGCCALHAAGANAIT
LADNSLATVRMSNMALGAMMKRLGVEPLLHIACRDRNLIGQQSHLMGLHALGIDQVLVIT
GDPSRFGDLPGASSVYDVSSFDLIRMVKQLNQGYAFSGKQLKQHAQFIVGAAFNPHVRHL
DAAVARLEKKVEAGADYIMTQPVYDAETIVQIYEATKHIPVPIFIGIMPLTSSRNAEFLH
NEVPGIKLSTYALEQMKLFTGEAARQEGNRMAKELIDVTLQYFNGIYLITPFNYYQMTVE
LTQYIRQQEQVKAGFKEVSSS
>A0A2D6LCT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MTRAEFKNRLQDNILLFDGAMGTMLYSRGVYISRCYDEVNISNPSLVGEIHQEYIKAGAD
VLETNTFGANRLKLGGHGLADRVAEINESGASLACAAARAAAGNVVLVAGSVGPLGVRLA
PYGQIGRKDALEIFGEQVSALVSGGVDLIIFETFSDMLELEVAVEAARKHHDLPVITSFT
VADNGTTLYGAEPAEAGKFLSSLEVDGLGVNCSVGPPVMMNALEGLLEVTELPVSIMPNA
GTPREVEGRNFYLASSEYMASYARKFIRAGARIVGGCCGTTPGYIKAMRNYIASFSPRKT
ISTRGNAGDGEATKVEPIPFGERSKLAASLAEGKFIRTVELIPPRGRDTQRILKSCGILK
EHGIDAVNIPDGPRALSRMSAQLLCVIIQESVGIETFLHYTCRDRNLLGMMSDMLGLSAA
GVNNILIVTGDPPKMGDYPDATAVFDVDSIGLSHLVAGLNRGVDLGGNAIGNPTGYLIGV
GVNPGAIDRAREMDRYWKKIGAGAEVAVTQPVFDPRILISFCSEVETANIPIIAGIWPLV
SLRNAEFMNNEIPGASVPEPTMERMRLADKNGSALEEGIRIAREAVQTIRPYVQGIQVSA
PFGKTEYALEVLKGLDD
>A0A509MKQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter halodurans|TrEMBL
MESQKQFNRRFSFEFFPPKTDQGKEKLQAVRDQLAEVNPDFFSVTFGAGGSTRDRTIDTV
LSLHNQGISTAPHLSCIGGSRESVAELLDLYMENGINRIVALRGDLPSGMGAGGELRYAN
ELVSFIREHSGDAFNIEVAAYPEFHPQARSAEDDLKNFVRKVKAGANSAITQYFFNVDSY
FYFIDRLEKMGVTIPVVPGIMPIVNYTNLARFSEMCGAEIPRWIRKQLEAYGDDSESIRQ
FGEEVVTGMCEKLLEAGAPGLHFYTLNQATASVNIWNNLGLAQRDKISF
>A0A316TKG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides silvaticus|TrEMBL
MTTGRGRSLGDILREGERSFSFEFFPPKDEAGEEQLWNAIRALEPYRPTFVSVTYGAGGG
TRDKTIGITGRIARETSLVPIAHLTCVGHTREELEGILDAYAAEGVFHVMALRGDPQEGP
RAEWTSTEGGLNYALDLVELARSRGDFRIGVAAFPEGHPNAESLDVDADRLVAKARAGAE
FAVTQMFFRASDYFALVERVRARGVDIPILPGIMPILNLNAIRRQGELIGTSVPEEVVER
ISAAGPDPADVRAEGIKLAAELCEELLAGGAPGLHFYTLNRSKATLEIFEALRITV
>A0A2U1VHM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. TSO35-2|TrEMBL
MTAPLSAPPSVSFEFFPPKTEKMEQSLWQSIQRLAPLAPSFVSVTYGAGGSTRERTHATV
CRIQDETGIPAAAHFTCVGATRDEIDGIARTYWDAGIRHLVALRGDPPETAGGVGGRYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDVYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPAKLAETFEGLDA
DPETRLLVAATVAAEQCQDLQAQGVNDFHFYTLNRSDLTIAICRMLGVKAKAAPAAVAG
>A0A2T4CDT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma longibrachiatum ATCC 18648|TrEMBL
MDRITDKIAALPADAEYFSLEFFPPKTQMGFSNLRVRLQRMERALRPLFVNVTWGAGGST
AQKSLELAELCQRELGLTTCLHLTCTNMSQALIDQALDDARALGIRNILALRGDPPRAEY
RDADEPTEASEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPYL
VDKVQAGADFIMTQLFFDIDAYEKFETTLRNHPSGAFKTIPILPGLMPIQSYAMIKRTTK
LSHAKMPDAIMDRLNVVKGDDERVKMVGVDILSELVEQIREIKSRTPGPKGFHFYTLNLE
KSVSFILERTKLIPDIPDEEEAVLDESPAVAAVQRMIPKINVNGNVPPRAPSHTRTGRRL
SSVGSDPHNRVIVGRAATHPEWEASSTEAGIPAGSVNTRANTLAISEGEGALGREATWDD
FPNGRFGDARSPAYGEIDGYGVSLHMSVTQAVRLWGYPKEASDINDIFVRHIRGEISAIP
WSEEDLLPESSIIKDKLEALNKKGWWTVASQPAVNGLPSSDPTFGWGPASGFVFQKSFVE
FFLPSADWKILYDKLTSEEVEEVVCFYATNAKGDFVSSDSTGGAGRAGGGESTNAVTWGV
FPGKEIVTPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSDSQKLLDGIREDYWLVNIIHH
DYVDTDALWRLLID
>A0A839NYX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. JUb56|TrEMBL
MKIVDHISNAKGKTLFSFELLPPAKGQGIQSIFKTMDALMEFKPPFIDVTYHREDYMYKK
HESGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDPDFIPTEGGHAFATDLLQQVADMNQGQYLHEDIAISEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVNKCRENDIHIPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSEAVSGCKNNADVRQVGEEWLVQQCKELIDFGAPVLH
FYTMSNPGPTKSIVEKLF
>A0A1H8TDQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas oligotropha|TrEMBL
MESQKKFPPAFSFELFPPQTPEGVEKLRLTRQQLARFNPKFFSVTFGAGGSTRERTLETV
LEIQTEGHVVAPHLSCIGSTQQNIRAILEKYYEAGIRHIVALRGDLPSGMAQAGEFRYAS
ELVAFIRQEYGSSFHIEVAAYPEYHPQARSAQADFDNFKRKIEMGASSAITQYFYNADAY
FHFVELCEAAGLNIPVVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLEGYGDDSESIQA
FGLDVVTGLCEQLLQAGAPGLHFYTLNSANLTSAIWQRLNLHAR
>A0A1C6CNY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MHPLFMKQKRLLFDGAFGTYYASLYGNEEPCEMANVKAPSRVAAIHEEYLKAGANAIKTN
TFAMNEAVLDCSKAKREELLRQGYRIAKRVATPYQASVFADIGPCVETRTRSAFTQYKEL
VDVFLEEGADCFLFETLPNDHGIHEIAAYLKERCPHVCVLVSFAVTADGYTQQGVPLTKL
VKAAHEDENIHGFGLNCICGPMHMRRLLKYFDTKKDTILIMPNAGYPTILANHTYFRDNS
SYYAQEMEKISSMGVRILGGCCGSKPPYIQKIKERLQEEAVLSLPTPAANDPVLYKDCNP
LRKKLQRKEKVICVEFDPPMDCRIERFMNDAEYLKEQGIDAITIADCPIARARVDSSLLA
CKLHRELGIDVIPHMTCRDRNINATKALLFGLNIEDIYNVLVVTGDPIPAADRQEVKGVF
SFNSQLLAGYIRDLNETTFPHPFLIFGALNVNAANFKQELLKAKQKIQQGVQAFLTQPIH
SAKGLQNLQQAHRELDAWILGGVMPIVSYRNALYMKNEIAGIEVDDAILSRYEHKNREEA
AVLAVTIAKATIDEMASFVDGFYLITPFHRVEIMQQIIAHIQQMDD
>A0A2A9CV92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionicimonas paludicola|TrEMBL
MPSPRPSIARLLAAGGRPTMSFEFFPPKDDAGAQTLLDAIDALEPLAPDFVSVTYGATGS
SRERTIEATRLISPRTSAITVGHLTCVSQSVDDLGAAIDAYTEAGVGHILAVRGDPPGGP
TAPWQRHPDGLDNATELVELVKSRGDFCVGVGAFPDAHPDRKDVELDARILADKQRAGAE
FAITQLFFDADAYFRLVERAGRHGADLPIIAGIMPVTTISQIERFAGFSGADLPRAVTDR
LHAVADDPAAVREVGVEIAVELCDRLLAGGAPGLQFFTQNRSRATAEILGRLRRIPPHTE
PVGSTDGE
>M2XB69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Galdieria sulphuraria|TrEMBL
MPSRGDINLRDTPKVHEKIKHRQDMGKIFFSFEYFPPKTPSGVDNLYDRIDRMSRVEPLF
VDVTWGAGGSTSDLTLEISGNIQRYFGLDVCMHLTCTNMPSGKVDDALNAAKERGIRNIV
ALRGDPPKGEEWHSIEGGFEHAVDLVRHIRKSFGEHFSICVAGYPEGHPAGLLEGNLTYE
QELHFLKEKVEAGGNFIITQMFYDTDRFLQFVKDCRSIGIEVPIIPGILPIQNYNGFERM
TKFCKTHVPDEVLKALQPIKDDDAAVKEFGIRLGIDMCRRILHSGLVPGIHFYTLNLEKA
VMSIIEGLDMIPKNQSIRSLPWRPATIDRRRHEDVRPIFWSNRPKSYISRTEGWDEFPNG
RWGDNRSPAFGELTEHHLLGSGGFRSKEEKEALHRAYGELKNFSDVSNIFLRYLSGEVSR
LLWSESDGLAKETMIIMEPLKWLNKHGLFTINSQPRVNGVPSSDIVFGWGGPGGYVYQKA
YIEFFAKREVVEALIEASKSYPLITIFAVSSKDSELLTNTKNLSSANAVTWGVFPDREII
QPTVVDPYSFLVWKEEAFSIWTELWGRLYEKDSTSQQILRHIHDNFMLVNVVDNDYVAGD
IFRLFDDVVPKFSLHDTELVANHVS
>A0A1C6APK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MNIRDIFDQKRLVFSFEVFPPKNTSPIKNIYKALNELVKLEPDFISVTYGAGGSTVNNKT
TEISSLIKNIYGIEALAHLTCISSTREQISDITERLRLEDVENILALRGDDNGTSCGDFN
YANELISYVKENKNLNIIAACYPEGHIENRDIKLEIDNIERKIEGGATSFISQLFLDNNI
YYEFLEEVYKRNIKTKIQAGIMPVINAKQMKRITELCGATIPLKFKKIMSMYENNPEALT
QAGIAYATDQIIDLSSSNVDGIHLYTMNNPYVAKSISKNIGKIINSINQVQNV
>A0A2S5Z7I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter maroccanus|TrEMBL
MTLVREQQAFNRPDEEAAALFRDLVRSASIEATPRQILATEHVPDLLPAGTCVYVPFLPR
GQFGDTLEASRRLLDLGMQPVPHVPARMAQSRGQLRDWLAQLDECGVDRLLLIAGDSDAV
AGPFPDTLAVLESGLLAQFRFHGIGVAAHPDGHPRADRATLAQALSIKREYARTTATRLW
VVTQFTFDAEVVIDWLQGLGNILEEVPVYIGMAGPTRVKTLIAYAAMCGVGASARMLLRR
PGSARMLGAWKPDDMVRALVQYCLENPETLLRGIHLFPFGGLRQSAQWIREHSGSVDDKK
EAVS
>A0A315SF30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia marianensis|TrEMBL
MQRLAEPHPGPVPFSVEFYPPRDEQAEARLWRTVRIFERMGPAFVSMTYGAGGSTRDRTL
RITGQLARETTLLPVAHLTAVGHSVAELRAMIGGYADKGITNILALRGDPPGDPLGEWVK
HPEGVEYAEQLVRLVQELGDFNVGVASFPEGHHRAPDLDHDTKYLVSKLRAGAQYSITQM
FFDVDDFLRLRDRVTAMDPEQGAKPLIPGIMPITSLASVRRMVELSGSVLPEAVDRRLAA
SAGDGSEENREAVRAVGIDLATEMAQRLIDEGVPCLHFCSLNFAKATSEVLERLGMNVMA
A
>A0A345ZYF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudolabrys taiwanensis|TrEMBL
MTRLQDKLAKGRFVLTAEVTPPVSFDRGELVAKASPLKGLADAVNVTDGAGARPHLGALT
AAATLLEQGIEPILQLTCRDRNRIALQSDLISAAAWGIENLLMLRGDDPSAGDQPDAKAV
FDLDTRQLTELARRLRDTSELPTGRKVTGKASFFLGAADSPIDPPPGWEPKGLIAKQTAG
AQFVQTQFCMDAGIVRRYMARLAEHGLAGKLSFLIGVCPLRSAKSARWMKEKLFGTIIPD
AYVERMEAASDPVAEGKRICVEVISELAAIPDVAGCHIMAPNNDAAVADVIVEARTLIKR
>A0A3A8EES7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter tianfuensis|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSSDHFKIEVAAYPEMHPQADSFDLDIKRFCDKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTDSIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>E1LPT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis SK564|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A101XXY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. DMB5|TrEMBL
MKPDLRSAWKNNVLVGDGAMGTFLYQKGFPVGISYEELNLNSPEVIEDVHRSYIEAGAVL
LESNTYSANYDKLAKFGLEGKVEDINRAGVRIARKAAGEAGYVVGAVGSIRAGKRANLSA
SELKRFYTQQFAALLEEQPDGIMLETFYDVEELHLALKAVRKLSNLPVICQLAVDETART
LDGLTLPEAFHVLEQDGADIIGFNCRTGPNGIKRALKTLQGSLALPVSVYPNAGIADYVD
GQYRYGATPDYFGQMAPVFADMGSRIIGGCCGTTPQHIAEISAALRGYVPQPLPEPAVKQ
SVHSITVHEHLEEDGGRSGREPNLVDLVKERHTVIVELDPPRDLDITKFMKGAEALRRAG
ADALTLADNSLAVTRMSNMALGSLVQARTGLRPLVHVACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVIGAAFN
PNVKHLDKAVQRLEKKIASGADYIMTQPVYDPELIANIAAATKHLDIPIFLGIMPLASGR
NAEYLHNEVPGIQLSDEVRTRMQGLEGEAGRAEGVAIAKELLDAATEHFNGIYLMTPFMF
YDMSVQLLEYIWAKQGRKLSPLFR
>A0A2N2GPJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-3|TrEMBL
MQAETKSPFGQSLRNPEQFTITLELVPSRGGHSREHDRTLELAEKLARDPRIQAVSITEN
AGGQAALSPEVLGREIQKMGLDVIVHFSSKDKNRNQMESLLFAWDRLGIRDLLVITGDYP
QEGYQGCPKPVFDLGSVHVLDLISRMNQGNYGPDRGKGAIQPTSFLMGVALSPFKRLEAE
LLMQYAKLHRKAERGANYIITQVGYDARKFHEAIQYVRQTGLNLPMLGNVFIPNLTVATL
MHSGKIPGCIITDRLYAEIRREAASPDKGKQTRLLRGAKLLAILKGLGYAGAHLGGPGLT
YENIDYLLSTADSLAGNWRDLVAEMNYWHQDGFYLYTKDAATGLNTAEPAPRNKRQPGLQ
VNYRMARLVHNLAFTKKAPLYPVCKKICLALEGGGLDNGLTHLEHVTKFLLFGCQNCGDC
TLGDLAFVCPQAGCAKYLLNGPCGGSRDGWCEVYPGKKRCLYVRVYERLAARGLPESMQK
GFVPPRNWALNNTSSWLNFFRGLDHAGKSQK
>A0A6J6RZJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTIGLGRSLADLIAAGQRSFSFEFFPPRDEAGEEQLWRAVRALEPYRPTFVSVTYGAGGS
SRGTTVRVTGRIARETSLLPMAHLTCVGHTREELESILDEYAAAGVRHVMALRGDPSDGP
RAEWTPTEGGFTYASELVELAAARGDFRIGVAAFPERHPSSPSLDHDADVLVAKAAAGAE
FAVTQMFFRASDYFDLVERVRERGADLPILPGIMPILNLDGIRRQGELIGTDVPEEIVAR
ISAHQGDPARMRAEGIAIAAELCEELLAGGAPGLHFYTLNFSRATLEIFEKLNVTV
>A0A6J7J557|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSTRPTISIELFPPKDSAGEERLWSAIASLREISPDYVAVTYGAGGSTRDRTIRITSEIT
ARTQLPTVAHLTCVGSTRDELIDVLNKYKSAGIRSILALRGDPQGGPSAAWTATPDGLDH
ADQLVALASEVGGFTIGVAAFPDGHPASQGNFDRDIEVLLRKEELGATFATTQFFFTAEK
YFDLVERLRSRGSHLTVMPGIMPISNVKQLIRMAELSGTPIPSDVEQKFLALDGDSDAVR
DYGRELATTLCQKLLAGGAPGLHFYTMNTSTATKEIFENLGL
>A0A7Y3SVM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium estertheticum|TrEMBL
MNIKELPLIFDGAMGTYYASIKENPLSKCELANIYDRNTILNIHKEYIEAGCKAIKTNTF
GANKISLESDFNGVKDVIVKGYEIASEATKGTDVLVFADIGPIPFLETLDLWEAYKEIVD
LFLELGATHFIFETFSSDEYLPEISKYIKEKNPKAYILMELAVSPEGFTRIGISGEKFIE
KVSNISSIDACGFNCFSGPYHLLKYIKTLNIKNKTISVMPNSGYPTVINNRTFFNNTKEY
FARQMLEIAKQGVAIIGGCCGTTPEFIRETVENIEGLSPNEIVPSIKIEKIKFEKLITKN
SLLEKIKLGKKIIAVELDPPMDTGIDFFMNSAKSLKEQGVDAITIADCPVARVRVDSSLL
ACKLKRELDITTVPHMTCRDRNINATKALLLGLSIEGVNNVLVVTGDPVPTAERDEVKAM
FSFNSAILANYITNLNETTFSSPFNICGALNVNAINFSSQLEHAKKKIENGVTMFLTQPI
LSKQAVYNLKQARRELPAKILGGIIPIVSHRNACFMNNEISGITVSDEITELYNGISKEE
ATILAIKISTDIAREIYDYVDGYYLITPFKRIDIISEIIKNIGSIGNY
>A0A094Q991|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRPEKTMYSFEFFPPKDLAGEDRLWQALETLALHAPDFVAVTYGAGGGTRDRTIRITSEI
TARTKIPTVAHLTCVGSTRVELIEILDRYRDAGIKSILALRGDPVGGPRAPWTAVDGGLT
HADELITLAREHSDFIIGVAAFPDGHPNSGGDFSKDIDVLIRKQSLGASFATTQFFFDVD
KWKRLVDTLESRGCDLPIIAGVLPVTNVKLLTKMAELGGTPIPDSIASRFAAVEDNPDDV
RKLGVEIALDLCNELIDAGVPGIHFYTMNSSTATSEIFTSLQERR
>A0A6J7NX70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRSLKSDGSKALTYSFEFFPPKDVEGEERLWAAMSQLESIAPDFISVTYGAGGSTRDRTI
RITSEITARTHIPTVAHLTCVGSSRAELLEILGKYRDAGIKSILALRGDPTGGPRAPWSA
THDGLNHADELVTLAAEFGGFTIGVAAFPDGHPSSRGDFNKDVEVLLEKEKRGATFATTQ
FFFSADKWKSLIDKLAAKGSSMPIIPGILPVTNVKQLNRMAELSGVPIPGHISDAFIKFE
SNPEDVRKLGVEIATELCNDLLEAGAPGLHFYTMNTSSATREIYSHIKDER
>A0A1C4FX25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVIDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIIAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6J6J144|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVVGTSYSFEFFPPKDIEGEGRLWHAIEGLKSIAPDFVSVTYGAGGSTRDRSIRIAREIT
NRTGIPTVAHITCVGSTRNELLEILNSYKDAKITSILALRGDPTGGPLAPWLPTENGFNH
ADELVELAKECGGFKIGVAAFPDGHPSSGGDFEKDIDVLIRKEKLGASFATTQFFFDVKA
YKNLVERLAKRGSALTIIPGILPVTNVKLLHRMAELGGTPIPDHIAKAFAEVESDSQAVR
ELGVEIATKLCKELLEAGAPGLHFYTMNSSTATVEIYRRINNVN
>A0A6J7A7Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MKSGLTYSFEFFPPKDVEGEERLWAAMSQLESIAPDFISVTYGAGGSTRDRTIRITSEIT
ARTHIPTVAHLTCVGSTRQELIEILGKYRSAGIKSILALRGDPTGGPRSPWSATPGGLNH
ADELVTLAAEFGGFTIGVAAFPDGHPASDGDIDKDVQVLLEKEKRGATFATTQFFFDAGK
WKTLVDKLEAQGSTLPIIPGILPVTNVKQLNRMAELSGVPIPSHISECFAKVEDNPEDVR
KLGVEIATKLCEDLLEAGAPGLHFYTMNTSSATREIYSQIKDER
>A0A1Z8Z4C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium TMED80|TrEMBL
MRIKDKIKRPRRPVVAYEILPPREKDGTLNSYAAKISSLLSQTHIDAINIPEVRDEAARG
ERPVKNQLRAEPREFGRLLQDIVGVEAIVNRVVVHQKLNEELKWLEETNKKYEIENLIIV
GGESRSIDYPGPSVNEALAAIKKNENINLLCGGISIPSREEESLKLVEKSENGCEFFTTQ
VLYDSSKIIKMISHYQKRCDEKKTFPRRLLLSFAPVSSEKNIKFLKWLGVEIPVEIEKLL
IEDLSKMTEKSMEIAVNVLQETLNHLNENNIIVPIGLNVEHIMSYNFQASIEMLQELSRI
YREFCIKTEIY
>A0A7Y0DMX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciimonas sp|TrEMBL
MSKENFSVEFFPPKTAEGTEKLRATRAKLTVLHPKYFSVTFGAGGSTQQGTLDTVLEIMG
EGLDAAPHLSCVGSSRESIRAILADYKAHGIRRLVALRGDLPSGYGGAGELRYASELVEF
IRSETGDWFHIEVAAYPEMHPQAKSPQDDLHNFVRKVQAGANAAITQYFYNADAYFEFLD
NAHKKGVRVPVVPGIMPITNYSQLMRFSDMCGSEIPRWIRLKLASFGDDSDSIKAFGLDV
VTQLCERLLAGGAPGLHFYSMNQSAPTSAILQRLK
>C1DCB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Laribacter hongkongensis (strain HLHK9)|TrEMBL
MSATPTISFEFFPPKTDEGRAKLATARKQLARFKPGFFSVTFGAGGTTREGTLRTVLDIR
AEGHAAAPHLSCIGSTRDNIRAILDEYRAHGIRHVVALRGDIPSGMGGVGEFRYANELVS
FIREHYGDHFHIEVAAYPEYHPQAGSAQADLDAFARKVKAGANSAITQYFFNADAYFRFV
DEAEARGVGIPIVPGIMPIYNFSQLARFSDLCGAEIPRWLRLKLAGYGDDVHSIRALGLD
VVTDLCDRLMSGGAPGLHFYTLNAAGSISTLCQRLGL
>A8F6Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO)|TrEMBL
MVFMKVIDCVKKGQILSIEILPPNRGQNIEEIYAVLDELMNFPISFINVTKHAPEMTYLE
LEDGIVKVPKVKRPGTVGMTAALMNRYNIDVVPHVLCFGMNKYQIEDMLIDLHLIGVRNL
FVIRGEYENQTIEEKDSYSHASDLVKQISNMNMGEYLYPCENAKPTDFCIGVAGYPEKHF
EAPNIEEDMRYLKKKIESGADYVITQMIFDFDVYKKFVERARQLSINVPIIPGVKPVVSL
KSIYTIPRKFFVNIPESFVKQMQEAKTHREEFQIGTKYMAKLVEKLLSSGAPGVHVFTMG
KGQSTKALLEAVFNR
>A0A328I6Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hapalosiphonaceae cyanobacterium JJU2|TrEMBL
MLIFMLDTQNPSCLTSFQTAAKAGKFLITAEVAPPKGGNPEQMLKMAATLKGRVHAVNIT
DGSRAVLRMSPVIASAILIQHGIEPICQIACRDRNRIGLQADLMGAHAIGIRNILALTGD
PVKAGDHPDCKGVFDLESVRLLQVIEKLNHGFDYNDKPLTDGALDLFAGAAVDPQCPSWS
GLQKRFERKLAAGAQFFQSQLITDFEILEKFMDKIAADCGKPILAGIFLLKSAKNAQFIN
RCVPGVNIPKHIIDRLAKAKDPLEEGMKIAAEQVQTAQQLCQGVHMMAVKREDLIPQILE
MAGVAPVNQMVLR
>E5C8P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. D2|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEIAKIIY
>A0A2G6MDV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus propionicus|TrEMBL
MQIQKKIQTAAPFVSLEFFPPKKKDDWPTFLDTVTQLKKLNPLFVSVTYGAGGSTQDNTL
DICERLVKDCAFEVMPHLTGVAAGQARVDTFLQALQSMGIENVLALRGDRPAGVSSSDEE
LFAAFPYASDLVRYVRREYPEMGIGVAAFPEAHAEASSIEGDLQVMRQKMEAGADFAITQ
LYFDNRVYFDYVQRLREMGVSIPVVPGVLPIRTLASLRFILDLCNAKVPGKLINALMQAD
ADGGSQAVYEIGVAYARQQVRDLVENGAPGVHLYTLNKADMCLEVMEGLC
>A0A7V2JQS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MESQQKYPKHYSFEFFPPRTDKGKTTIAKTLDELSKLKPAYMSCTYGAGGTTQVGTYDTV
KLIVDRQQTAVPHITCIGSSKGVICNLLKTYTELGVKRVVALRGDLPQGQSDPGEFHYAN
ELVTFIREEMGEDFGIEVACYPEVHPQAPSARADIENFKRKVGAGANCAITQYFFNIDAY
FRFVDECEQSDIHIPIVPGIMPITNYTQLAKFSDLCGAEIPRWIRKRLEDYGDDLESIRA
FGLDVVSELCRRLLDAGCPGLHFYTLNKHEPIVALWQRLGLKGPV
>A0A6N3ITJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium collinsii|TrEMBL
MKVTEHIENAKGNTLFSFELIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNRFAIDLVRQINDLNRGKYLHEVMDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFTFVEKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIARQIF
>A0A439XE16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MTIRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A2S8NWJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. PCH8|TrEMBL
MKADLRKAMQERVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEV
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFADLGARIIGGCCGTTPDHITAIKEALAEFVPLPILEPDPSE
FKPRIVLHENVDERAGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAEILKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLEKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A668UN38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oreochromis aureus|TrEMBL
MVNQVQRGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRYFWPPVDPCWGCCVPLCFFYRFDRMGSGGPLFIDITWH
PAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQSKEKITGYLAKAKHLGLKNIMAL
RGDPVGEDWEEEEDGFNYAIDLVKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKE
KVDAGADFVITQLFFRPDTFLKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEV
PEEITQVIEPIKDNDAAIRNYGIQQAVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQL
GLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPA
FGELNDYYLFYLKSKSSKDALLQMWGEELQNEESVFEVFTSYITAQPNHCGHKVMCLPWN
DEPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFF
TSSENVTALLKVLKKYEPRVNYHIVNVNGRNLTNAPEMQPNAVTWGIFPGREIVQPTVVD
PVSFMYWKDEAFALWIEQWGKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVI
DDMFELLDAPPELHSEETV
>A0A0D0DKV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paxillus rubicundulus Ve08.2h10|TrEMBL
MKLSEKIAAHISPHPFYTFEFFPPRTDQGFENLISRISRLSTLHPIAISVTWGAGGSTKD
RSLDLAGLTQSEYGIDTILHLTCSNMLPGMVDDVLRAAKARGIQNILALRGDPPRGEEHW
TPIDSRFTSGLDLVKYIRSSPEFSSYFCIGVAAYPEGHPNNETDEEGNFDILKQKVDAGA
DFVVTQLFYDADRFIDWVKKVRSKGITVHIIPGVMPIQTYSSFLRVIKLCGAQVPPKIMA
DLDAIRHDDKLVKEYGVCLAVDIICKITEGSLVPGVHFCTLNLEKSVQLVLESLQWADGG
PVVRNQLIADSPAPLLHPPLPRSDLVITPSNATTTAANALTSKPILEVEPPGRGELNNAA
TWDDFPNGRFGDYKSPAFGAQDQWGGLGINVYAVQPHWGDPSTIEELTELFQDYLDSKVS
TTPFSSSPLSSESETILDSLKKLTSKGLWTVCSQPAIENVNSTDEIFGWGPRGGYVSQKG
FVEFFAEERVVDQIEQKIQKEGSGWVHFFAANVQGECRTNVPEHGRNAVTWGVFPGQEIV
QTTIIEQESFLTWKDEAFAIWAEWASFYAPDSPHRTLLDKVRKERWLVSIVHHDFKRADA
LWSFLLDEGDHL
>A0A2S6RX98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha9_Bin6|TrEMBL
MTDSDAGTLDDSRSTHSQGRLERLLRAGAFVVTAETTPPVSADPAALLEVTEDLRDWADA
VNVTDSAGAKSHMASLVAASLLMRAGIEPILQFTVRDRNRIALQNDLLGAGALGISNILC
LTGDNISAGDQPDAKMVMDLDSRGLVSLARDMRDSRQLPTGRPIEKAPGLFIGATDAPQE
PDNEWSATALQSKVDAGAEFFQTQFCFDIDLVRRYMERLENEGVLERAYFLIGIGPIASA
KSARWMNQNLFGVDIPESLIGRLEQATNQQAEGRRVCLELIQQLREVTGVSGVHLMGPQA
ERSAAQVIADSGILNERPEVA
>A0A531ZX91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKAFMQSARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHHEITETQVDMVK
TAH
>A0A439ZQB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MEARLWDTVTRLEPLKPKFVSVTYGAGGSTRERTARTVKRILNETTLTPAAHMTCVDAAR
DQVDAVVREFADMGVTRFVALRGDPAAGVGTAYRPHPDGYANGAELVGAMKSAGDFDISV
SAYPEKHPESPDFATDFDMLKRKADNGATRAITQFFFDNDLYERYVERARRAGIYIPIVP
GILPVHNFTQVANFSARCGALVPAWLAERFEGLQNDPQTHALVASAVAAEQVLDLVERGV
SDFHFYTMNRADLVFAICHMIGIRSHEAEAAGSAAA
>A0A3S4T5F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium nakagawai|TrEMBL
MKITEHIQNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINNLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A068RES7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lichtheimia corymbifera JMRC:FSU:9682|TrEMBL
MKITDKLEQAKQKGHISYSFEFFPPKTDAGLANLFDRMGRMATLEPYFVACTWGAGGSTQ
QRTLEVCSTAQSVYGLETLMHLTCTNMEKEKIDRALEDAKAAGIQNILALRGDPPRGQEY
WTPCDDQFQHAADLVKYIRQHYGDYFCIGVAGYPEGHMDTPDKAQDLQYLKDKVDCGADF
ILSQLFYDVDVFKTWVKKCRDLGITVPIIPSILPIPTHQSFRRIINLCRIQVPKAILDKL
EQIKSDDQKVKDYGVELAVDMISDLRASGLIDGIHLSTLNLERSSRLILERLKLAPSKKE
QPKNRVLAALASDASLVENWDEFPNGRYGDARSPAFGENTYIATQLAPTSEAAKKWGHPT
TVQDITRLFERYITGDLSSLPWCDEPLQTESDTIQQHLTQFNRQGYWTVGSQPAVNGARS
EDPVYGWGPKGGYVYQKAFIECFVSDEQLHKLLERLKKDPHVTYYATNRKGDLSTNVENT
EDQNAVTWGVFPGKEIVQPTIIERVSFEAWRDEAYQLWKEWEQQYPADSKTAQLLRDIAE
RYWLINVVHNDFQQPSSLFEAMLP
>A0A529FGV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
DPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRARIFDGWVDAINAVDASGA
NCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAAMGVANMLCLTGDGVQAG
DQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFLGAAVNPFAPPF
>A0A531MIW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
VLQAVEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVAGSAAA
>A0A2K5I2B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colobus angolensis palliatus|TrEMBL
MVNEARGNGSPNPCLEGSASSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDLCVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIERWGKLYE
EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNERETETP
>A0A529TPR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTART
>A0A528UBZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPXXXKPKFVSVTYGA
GGSTRERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFAEMGVTRFVALRGDPA
EGVGAAYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDN
GATRAITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWL
AERFDGLQKDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSH
EAEAAGSAAA
>A0A442BIW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWQREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A531MCJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
PFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILCGVGPLASAK
TAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSGIHVMAYRQE
EYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHDEITETQVDMVKTAH
>A0A1I0H5Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster lavalensis|TrEMBL
MKISELYQTKQNQETPSKKTLSFEIFPPKKDSELKNIDKTLSVLCELNPDYISVTFGAGG
GANRNRTIELAKRIKQEYHVEPVVHLTCLHYDKAEIDEFARVLTNAGLQNVLALRGDKNP
NMREKESFLHASDLIAYMKDKWDFCFLGACYPECHPESEDKVCEIKHLKAKVNAGAEVLL
SQLCFDNHAFFRFQEACRIADIQAPVIPGIMPVINAAQIKRMITMCGATFPVRFQKIIQA
YESNKEALFDAGMSYALSQIIDLLVSDVEGIHLYTMNNPLVARRICEGIRNII
>A0A1Z2LKA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. WZN-1|TrEMBL
MPAGISSQAEAFINAFSLEVSAKAMPALRAEAARIPCGTVISIPWLASEDDDARLAAACT
VRELGFEPMQHLSARRIGSHAALERFLQRATSEAGVTRCLLVAGDLATPAGPFADSASII
QTGLLEHFGIKVVGIGGHPEGHPVMSNDDRWRVLERKCQAIEARGMTPMIVTQFAFDADI
VLAWLDALRARGMAVPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGISFGRLLGTA
GPEVFVDRLVKGLTDAHGPVSPHFFPFGGIAPSLEWVAQYRRSVYSNGG
>A0A2E6SHW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIRDKVKKPKRPVVAYEILPPREKDGTLNSYAEIISSLLSQTHIDAINIPEVHDENSRG
DRPVSSQKRGEPREFGRMMQDIVGIEAIVNRVVVHESLEIQLKWMEQTNKEFEIENMIIV
GGESSSIKYPGPSVNEMLSAISSDFNSNGGDIFCGGIAIPSRVKESMNLIKKTNHGSEFF
TTQVLYDSAKVIKMIDFYQKQCDESKTFPRRILLSFAPVSSQKNIDFLKWLGVEIPDETE
RYLQGRPGSMTERSLDVAIEVLNDTLNFISANDLKVPIGLNVEHIMSYNFQSSVEMLQEL
ARIYREFCIKTKQY
>A0A7X0F4P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter aganoensis|TrEMBL
MNQYPLSRRSDIGNKIRVSFEFFPPKNDEMEARLWDTVTRLEPLKPQFVSVTYGAGGTTR
ERTARTVKRILQESTLTPAAHMTCVDATREEVDQVIAEFAAMGVKRFVALRGDPKEGVGA
AYQPHPGGYANGAELVGALKAQGDFDISVSAYPEKHPESPDFATDFDMLKRKVDKGATRA
VTQFFFDNDLYERYVERARKAGIYIPIVPGVLPIHSFAQVANFSARCGAHVPYWLAERFE
GLDRDPQTHALVAAAVAVEQVLDLVERGVSDFHFYTMNRADLVVAVCHMIGIRPQPAVQG
SAAA
>A0A838EIW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ktedonobacteraceae bacterium|TrEMBL
RNLMALQSDVIGAHATDIRNILAVTGDPPNHGDFPNATGIWDVDSIGLIAILNKLNQGLD
ARGRRLAVPSFFHIGGAANPTATDVERDIERLHQKIEQGAQFIMTQPIFDVATLQDYIEQ
YTQRYGKLPVPLIVGIQPLHSYQQAEKFHNEVPGIVIPEGMRRRLSEAGEAGSTVGVEIA
KEMIDEVTSFVQGVYLMPLERFELVSEMVPYIHRRVKKI
>A0A7C7GQ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
FKAQGKTFYSFEFFPPKTDFGLDNLYSRIDRMASLQPAYIDITWGAGGSTSNKTLEMCKT
IQKYFGLEVMMHLTCTNMQVSSINKVLIEAEKNDLSNILALRGDPPEGSSSWEQHEDGFR
HGVDLVRYIRKEFGDHFFLGVGGYPDGHQEQSDLDADISFLKEKVEAGADIVVTQLFYDV
DKFLFFRDKCIKAGIKVPIIPGIMPIHNYARFLKFTQFCQVSVPDSVTEQLELIKYDDSS
VINYGIDQASGMCQKLIKNGVPGLHFYTLNLENSVSAILKSLGLVSSQGIIKELPWRQST
SDDRKTSEDVRPIYWSNRPVSYLTRTEIWDDFPNGRWGNIESPTFGELNQYHAIRAGSRS
DKIKAKRKKMWGEPKSIKDITDVFVSFCKGKINSLPWCEIPLAQESKQISDDLLNLNEME
YFTINSQPKINGLPSEDAEAGWGGPGGRIYQKAYLEFFTSKDKLDRLLKSIGSKENISYE
AININGDLITNLPENNVMAVTWGVFPNKEIIQPTIVDMRSFLIWKDEAFSLWMDDWASIY
EAKSESYKLIKEIYDTYYLVNIVDNDYVDGDLMQQILKS
>A0A1Y4QJ60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] spiroforme|TrEMBL
MKIIDLLHKRPTLSFEIFPPKNYDGDISSIYQTIDELSKLKPDFISVTYGAGGSTTKNTV
EIASKIKNDYNIEAVAHLSCIDASPKQLTKIIDALKENKIENILALRGDYPKDYDPKNTC
HYFKYASELNEFITKNYPDTFCLSGACYPEVHQEATSLENDLDALKKKVDAGAQYLITQI
FFDNNYYYRLLREARIKGINVPIIAGIMPATNSKSLLKIAKLSGSNIPYNLSAMIERFKN
NPKAMKEVGINYAVYQIIDLITNGVEGIHIYTMNRPEIAKEIIARTDNILKEFIND
>A0A8D0ALD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sander lucioperca|TrEMBL
MVNQVQRGDGSWQSCKSDSSGASNSSESSKESSRSSTPVLDVDRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGTGGPLFIDITWHPAGDPGSDKETSSLMIASTAV
NYCGLESILHLTCCNQTKEKISGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATD
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNY
GIKQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LKMWGDELMSEESVYEVFTCYITAQPNRSGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIAGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVN
YHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWKVIDDMFELLDKKLTRALLW
>A0A2D5PY90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEIIANYKAQGKIFYSFEFFPPKTDFGLDNLYXRIDRMASFXPAYIDITWGAGGXTA
DKTLEISKTINKYFGLEVMMHLTCTNMQVSSIKKVLIEAEENGLSNILALRGDPPEGSFT
WNQHEDGFRYSVDLVRYIRKEFGNHFCLGVGGYPECHHEQSDLDADISFLKEKVDAGSDV
VVTQLFYDVDKFLFFRDKCIKAGIKVPIIPGIMPIXNYARFIKFTQFCQXSIPDSVTXQL
EXIKYDDSSVINYGIDQATAMCQKLIENGVPGLHFYTLNLEHSVSAILKSLGFVSSPGTI
KELPWRQSTSDDRKTSEDVRPIYWSNRPVSYLTRTEIWDDFPNGRWGDIESPTFGELNQY
HAIRAGSKSDKIRAKRKRMWGEPKSIKDITDVFVSFCKAKINSLPWCEMPLALESKLISE
DLLKLNEMGYFTINSQPKINGVPSEDAEVGWGGSGGRIYQKAYLEFFTSKDKLDKLLKSI
GSKENISYQAINISGDLITNLPENNVTAVTWGVFPDKEIMQPTIVDTRSFLIWKDEAFSL
WMNDWASIYEAKSESYELIKEIYDTYYLVNVVDNDFVDGDILKQIVKS
>A0A2E5JNC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEKIADYIAKDKTFYSFEFFPPKTDFGTENLYSRIDRMASLHPAYIDVTWGAGGSTA
DKTLEMCKTIQKYFGLDVMMHLTCTNMGESSIKKILMEAKESDLSNILALRGDPPEGSLT
WEKHAEGFRYGIDLVRYIRKEFGDDFFLGVGGYPDGHQEQTDINVDIKFLKEKVDAGSDI
VITQLFYDIDKFFLFRDKCVKAGIKVPIIPGIMPIHNYARFLKFTQFCKVSIPNLISKQL
ESIKDDDSSVINYGVDQASEMGRVLIEEGVPGLHFYTLNLEHSVSEILRSLNLVSSQGII
KELPWRQSTLGDRKTAEDVRPIYWSNRTVSYLARTESWDDFPNGRWGDITSPTFGELNQY
HAIRAGAKSDKVKAKRKKIWGEPKSIEDIKDVFVSFCKGEINCLPWCEMPLAHESQQISS
SLINLNEMGFFTINSQPNVNGAPSEDAIVGWGGSGGRVYQKAYLEFFTSNDKLDTFLKNL
KSTDNISYQAINIDGKLITNLSENSVMAVTWGVFPGKEIMQPTIVDTRSFLIWKDEAFGL
WMNDWASIYDQESESFKILQEIYETYYLVNIVDNNYVDGGMMEQFFK
>A0A7V0T973|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVTEHIENARQPLFSYEILPPRRGHSADKLMQIVNELLPLQPPYIDVTSHSARMLTKKC
ADGSSRQIVRKKRPGTISICGVIQNRYHIDTVAHLLCQGFSREETEDALIDLNFLGIQNV
LALRGDTLAYEKDLAPDRSLNNYAADLVTQIHKLRQGEYLEGGQPGDIIDMCIGVAGYPE
KHYESPDIETDIQFLKEKIEAGADYIVTQMFFENASFFAFVERVRAAGIQVPVIPGIKIL
RNLRQLERLPETFHIHIPEELKGEMLSAPEYGSEIGIRWAHRQVEGLLASGVKNIHFYIM
NEVESVKKTLKKFTI
>A0A8J3KI14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catellatospora coxensis|TrEMBL
MSPQAPYGAAGAGGAREHGHAGRAHHALGRNRSSSRCADRVGRVTLRAPSTMPGPRPTVR
ELLESGEPTFSFEFFPPKTADGERLLWQSIRELESLQPSFVSITYGAGGSTRDTTVQLTE
RIATETTLLPLGHLTAVNHSVGELRNVIGHYSDAGVRNMLALRGDPPGSDPQAEWVAHPR
GLHYAEELVRLLKDSGDYCVGVAAFPEKHPRSADFASDVRHFVGKCRAGADYAITQFFFD
WQDWARLRDAAAAAGCAAPIIPGIMPVTNVSQIERMAQLSGAAFPPDLAERLRAVADDPR
AVRAIGVEVATELSAKLLAEGAPGLHFITLNRSTATREVWQRLRVGAAV
>A0A1H3FQ09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobellus clavatus|TrEMBL
MALGTQRDAEAGVEFLLREARFELMPFDSFDDEIQELPEGSSIAITTSPKLGIEKTVERS
EDAAAAGYEVVPHIAARYIDGPEQLEEVCRRLTEAGITDIFVPGGDKEEPVGEFESAYDL
LVALDDLEYEFEEVGITGYPEGHDFIGEEELAESMEKKAPYATYIVTQLCYDPDAILEWI
EDIRARGVDLPVEVGIPGVMNYQRLLSISQKVGVGDSVKFLRKTTGIFGFVKQLVGSRGR
YKPDDLIEGLAPYVNDDEYKIRGVHIYTFNQTPDLENWRQSRLQN
>A0A4V2BA79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriaceae bacterium|TrEMBL
MFFEKIRSGESGILIYGITPPKTQTLPERVTEIAQKTIERLEKLDIDALIVYDVQDESAR
TNEERPFPFLTALDPFEFAAGYLGALNIPKIIYRPAGKFSEEELTTWLEQLHQNKFYPVF
VGVPAPDFPVKTSLPQAYKIWSKYQDSSVIGAVTIPERHAVLKDEDVRILDKMSCGVSYF
ISQCVFNIDYAKQVIEDLTNTCNNRNIKFPTVVFTLTACGSAKTLHFMEWLGIHVPDELK
EELKASENILERSVQVCLDIAKELIVFCMERNIPFGFNIESVAIRKEEIEASVAMTNDIG
QMLKDKGLRK
>A0A5E7KZE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCDRLLEGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A4D6XWQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MQNFSKYHQNIVYQKKENLGHIINCSFEFFPPKSINLEKNLWFSVEQLSKLKPKFFSVTY
GANSGERLKTYEIVKKINKKTQVITAAHLTCVDSTPDELKRIAQDYWNNGIQSIVALRGD
TLKKNYRHKMYALDLVILLKKIADFDISVAAYPELHPESKDAKFDIMSLKKKIDAGANRA
ITQFFFNVESYLRFRDNCIKNNINVEIIPGILPVYNFQQLQRFAEMTNVHIPKWMFEIFY
GLDDDIAVQKIIGSSIVIDMVKNLSSEGVKNFHFYTLNQSEVIYSVCRMLGL
>A0A2E1QHX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIRDKIKKPQRPVVAYEILPPREKDGTLNSYAETISSLLSQTHIDAINIPEVLDEAGRG
DRPIANYKRGEPREFGRLLQDIVGIEAIVNRVVVHDDYDTQMRWLEETNLVYEIENMIIV
GGESSNVKYPGPTVNQTLEAISXTYNKKGKDIFCGGIAIPSRKEESKNLIKKSKNGSEFF
TTQVLYDSKNIIKMMNNYQTRCNELNTFPRRILLXFAPVSSQKNIDFLKWLGVEIPEGTE
KYLQGRPGSMKERSLDVAIEVLNEILVNIEENNLKVPVGLNVEHIMSYNFQSSVEMLQEL
ARIYREFCIKTQNYSI
>A0A1Q4E4D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. 67-41|TrEMBL
MAAPLFADVAGDIDVSFEFFPPKTEKMEETLWESIETLGPLGPRFVSVTYGAGGSTRERT
HNTVARIARETAIPAAAHLTCVEATREEIDQVAREYWAAGVRHIVALRGDPPRAGEKYGT
HPGGYENAADLVAGLRRLHPFEISVAAYPECHPDSPNQAADLDNLKRKIDAGATRAITQF
FFEPETFLRFRDDAAKAGIDAEIVPGIMPVMSFASVVRMAGMCGTQVPGWMERLFEGLDE
HPAARQLVAATLAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGVRPKVAALAAA
>A0A416LSX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. AF25-13LB|TrEMBL
MNIKEYIKEQRLITDGAMGTYYEEKYSEDTVIAEKENLKNPEQIKEIHLEYLRAGARLIR
TNTFAANTMFLADMQEVKETVRAGYEIAKEAVASFQAENGKEIPVFIGADLGPIYDLDHQ
DYDNVLQEYKEICDTFLSCGADCFVFETQSDFTYIEPVTAYIKEKSDAFILVQFAFDKSG
YTRSGLSMQRVAVEASEMENVDAYGFNCELDSTHMYQFMKNLKFSSDKFVSALPNAGYPY
TLRGKTIYSNNASYYAEKMKDIAALGTDILGGCCGTTPEYIALLSGELQDVPKAAKKIEN
VVTQEVTRTPSIFEEKLSRGEKAYIVELDPPFSEDASKVMKGAEDLRKCNVDLITLSDSP
MARARMDAGQLAVKIQQKTGVAVMPHISCRDRNVIALRAGLLGMHMNDVRHFLIVTGDPV
SRADRERVTSVFDFNSIKLMQYVKEMNLEVFAQEPVYYGGALNYHGANPDAIIERMKRKA
EAGCGYFLTQPVYTEEDVERLTYIKEHIDTKIMCGIMPLVSYKNAMFVKNEMPGIHVSDE
IVNRYREDMTREEAEEVAIELSVEIAAKLYDIADGFYFMTPFNRTGLIARIIEAIRQEEE
RR
>A0A7X6MCX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis alborubida|TrEMBL
MAPRGPAARPRHIRELLDAGEPMFSFEFFPPRTPQAQERLWRAIREIEALGPAFVSVTYG
AGGSTRGLTVETTERIATDTTLLPVAHMTLVDHSVAELRHLVGRLADAGVSNMLAVRGDP
PGDPDGEWIAHPQGLTYAEELVRLIKDSGDFCVGVAAFPFKHPRSADVETDTDHFVRKCE
AGADYAITQMFFDPEDYLRLRDRVAARGCEVPIIPEVFPVVRTSFIPRSEQLSGAPFPAD
LAERFASFGDDAESVRAFGIEHAQRMCERLLAEGAPGIHFITSNRSTATRQIYREISGHR
SPSEGAGRP
>A0A8I1HZL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp. PB-SRB1|TrEMBL
MSFAKRLAAREFVVLAEMHTPKGVNITRLVNDARRIKGRVDAVVIPDMDNGIMRMSSLAG
GVLMQQQGVEPIIHLYCRDRNRLALQGDILAAHVMGIQNLLVTHSEPMDQSDHREAREVY
DLDELALVQAIDGLTRGVDLGGFELDGAPAFTTGCTIGSYADEAALDNELTAARAKIEAG
ARFIIAPAVFDLAGFKSFMEKASALAVPIIPTVFLIKSLAIAQYIAASEPEAGISDELIR
RIRKSSDRELEGIKIAGEMLVGVRELAQGVMLQTLGWEHKLPDILDAASM
>A0A7L6A2U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dechloromonas sp|TrEMBL
MKPEISIEFFPPQTPEGMEKLRVTWARLAELKPAFFSVTYGAGGSTRERTFAVVKEIAAQ
GLPAAPHISCIGSTRDKIREILDEYRAAGIRRIVALRGDLPSGMAEAGEFRHANELVEFI
RAETGDWFSIEVAAYPEWHPQARSSQDDLAAFARKVRAGANSAITQYFYNADAYFHFVDE
ARALGVDVPIVPGIMPIAGFSKLARFSDACGAEIPRWMRKKFESFGDDTESIRAFGLDVV
TELCQRLLAGGAPGLHFYSMNQSALTTEICRRLG
>A0A316VSE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceraceosorus guamensis|TrEMBL
MTPSLSSPPAPLSPTQQQQQQDGKQEANTDWRITTKIAKAEREGRIWWSFEYFPPRTAQG
LTNLYDRIERMADLGPAFVDITWNAGGRTSDLTAQLVKTVHTYMGLETCMHLTCTNMPRS
KVDVALREAKQFGCRNILALRGDPPAGGGAWEKHEAGFEYAKELVQYIRQGYGDYFAIAV
AGFPEGHPESLEGKKMELERLKDKIDAGADFIFTQMFYDFDIFAQWVRDVRAAGITCPIV
PGVMPIQTYGGFQRATARFRTIVPQYFHDALEPVKDDDAKVREVGTQLVGDLCRRIIDPK
EGLRISGLHIYTMNLERGSRMLLDYLALSPSPQQVKALPWTPSLTPKRRDEGIRPIFWAN
RAKSYVDRTETWDEFPNGRWGDARSPAYGDVDAYGVKLRYSEAEARELWGEPTSLEQVKQ
LFTGFCKGDIKALPWSETAIAKETTVINDKLVSMNQKGFFTINSQPSVDGARSDDPVHGW
GPKNGYVYQKAYLEFFVAPSQVDGLISKLEQDPQITYHVVNARGDMRTNTTSEAPCAVTW
GCFPHKEIIQPTIVESISFLAWKDEAYEIGRHWARVYPPGSQSRRLLESIFGNASGDVTP
GTSPDLQADQSWFLVNVVHNDFKNKEAVFAPFLDAVDLSAAVAAAATTASLENATETARN
VASGAANIAKSIAEKATAPLANGHVA
>A0A256FEA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella rhizosphaerae|TrEMBL
MGFYGLSRRSDIGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLKPKFVSVTYGAGGSTR
ERTTRTVARILKETDVDAAAHLTCVDATKEEVDEVVREFAALGVKRFVALRGDPASGIGE
KYVSTPGGYQSSAELVAGLRQIDDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNELFERYVERVRRAGIYIPIVPGVLPIHNFKQVKNFCARSATHIPAWLAERFE
GLENDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPNTETAL
QVA
>I4YVE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga lotononidis|TrEMBL
MSPLALRPSRQNASPIKVSFEFFPPKTPEMETTLWSSIQRLAPLHPHFVSVTYGAGGSTR
ERTHATVSRILKETPLKPAAHLTCVAATKEEVNDVVRSYWDAGVRHIVALRGDPVGGIGT
AYEPHPGGYRQTCDLVAGIKAIGDFEVSVSAYPEKHPEAASLDADIDALKSKVDCGADRA
ITQFFFDNDLYFRYLDRVRARGIDIPIVPGIVPVQNFKQTANFASKTGASVPGWLAARFE
GLENDVETRKLIAAAVAAEQVFDLLDRGVSEFHFYTMNRADLVYAICHLLGLREQSVKAA
A
>A0A2N0LQJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G6|TrEMBL
MVKVTDKCFESTGRTSIICDFSPPRSGDPSVVDQARLDVDFLSVAYNPGRAVRANSAMLA
AAIQQSGRDTVFTLATRDMNKLAVQSQLLGAQMLGVQNVVVVQGDNFNERDRSIVATVND
YHPTGLIADIARMNEGQDFREGKLRTPSDFCIGAAVDLGRGIEDEAQLAVRKVKAGAMFL
ITQPIFHVDHVARFRESYGGHAGAGGALPIYFGLQILEQDGVLFSSVPDSVRSELEGGRS
GVDIALELYQKFQEARLHNIYLMPPIKRGGARNYGAAKEFLTSAKKI
>A0A1V4QDL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-3 bacterium 4484_100|TrEMBL
MLRDKLARSKIITLEILLPISCRVKDLLEQLARFKAYVDAFNIPSNPLGKLRPDALCYGH
IIQENLGIETIPHFVARHFTSLSFESHLLGASALGIENILCVTGDTPAEGRSSFELNSQK
LLEIARNLSAGITSSRKAIPPVDFCLCTSFNPNVVNVRGEFIKSKGKLECGAEVFFTQPI
FDTEKFLRIISEFRRAHSKAKVIAGLSFLYSKKRAFKLMKFLGIPYKYIIELDKRDELAI
LYETAERVEKFVDGFYIIPIGRYEPALNLIKKIKELIH
>A0A087DSK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium stercoris JCM 15918|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVDEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREKRPNLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCESRVPEKLAVLLDKWGSDTALLKEAGIAY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A1V2PRB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. ALI-6-A|TrEMBL
MTTQQPYPRSRPAAMSLAGLVRTATVEIIPLKGADAQIQAAPADATVTVTCSPKFGLART
LEYCAIATRSNRRVVPHLAARMVENRAALREFVARITDLGVTDLYVIGGDGDRPVGIYSE
ASQVLEDLRGLDHGLTRLGVGCYPEGHPTVDDDRLWESLARKQKLATYMVSQLCFDARAL
EDWLLQARGRGITLPLRVGVAGPLKVAKLAELSLRIGVGQSLRYLSKQHGLVGNVLLGRT
YDPEPFVDAVGKIGSADGSGIEGLHVFSFNQVAQYAAWRAAAVPPTAGGQVS
>A0A3C1Z4F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPRRLRDVLAQGQFAVTVEYNPPKGTNLTHVVDSAKSLVGRVHGVNVTDNTAAIVRA
GSLPVCRVLYELGHDPVMQLTCRDRNRIAMQSDLMGAHILGIRNILCLTGDYPTVGDHKD
AKPVYDLDSVQVMQLVTGLNNGKDYAGNKLDGSTAFTIGGAVTPEADPLGPMLVKFEVKV
RAGAEFFQTQAIYQPEQFKKFMEAVRPFKVKVLAGILLLRNAKMAEFMNANIPGVCVPQD
MIDEMRAAGDKRALDAGVEIAVRTIKAVRPYCDGVHIMAIKSTERLPEILTKAELG
>A0A3P8NCE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Astatotilapia calliptera|TrEMBL
MVNQVQRGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQSKEKITGYLAKAKHLGLKNIMALRGDPIGEDWEEEEDGFNYAID
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNY
GIQQAVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELQNEESVFEVFTCYITAQPNRCGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVNGRNLTNAPEMQPNAVTWGIFAGREIVQPTVVDPVSFMYWKDEAFALWIEQWGK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPELHSEETV
>A0A8H9BBT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia albertii|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSCLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A415CY13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM09-41|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRSHADIAAKIDEYRSAGVENILALRGDLPAGAT
EDDKPASDYAYARELIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A3A9VYW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces radicis|TrEMBL
MALGIASRMTGRAPTVRDLLAAGERSYSFEFSPPKTEKGERTLWSAIRRVEAVGPTFVSV
TYGAGGSSRERTVRATERIATETTLTPVAHLTAVNHSVAELRNIVGQYAGAGIRNMLALR
GDPPGDPMGEWTRHPEGITYAAELVRLIKESGDFCVGVAAFPEMHPRSADWETDIRHFVA
KCRAGADYAITQMFFYPEDYLRLRDRVAAAGCATPIIPEVMPITSVRQIERFTQLSNAAF
PPELERRILAVKDDPMAVRSVGIDFATELCARLMEEDIPGLHFITLNTSVHSTATLEVYK
NLGLHQRT
>A0A258QUX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 35-66-30|TrEMBL
MAGPIRASREIGKAPVGVSFEFFPPKSEEMERNLWTSVARLAPLAPRFVSVTYGAGGSTR
ERTHATVERLVRETDLAPAAHLTCVAATRAEIDDVVRAYAKAGVKHIVALRGDPTSGVGT
TYEPHPDGYAHACDLVAGIRRLGDFEVSVSAYPEKHPESPSIDADIDYLKEKVDNGATRA
ITQFFFDNDVYFRYLDKVRARGIDIPILPGILPVTNFKQAANFATRTGASVPDWLAKRFE
GLDNDPETRKLIAAAVAAEQATDLVDRGAEQATDLVDRGAGDIHFYTLNRADLVYAICHL
LGLRDKGVASTAPQAIAV
>A0A0D0H505|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. MSHR3999|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTGLCQRLLDAGVPGLHFYTLNSAAATKTICERLGV
>A0A222FGJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacterioplanes sanyensis|TrEMBL
MTTLSFEFFPTKTDEGTQKLLRVRDELAQHNPEFFSVTYGAGGSTRDRTYAIVKAIQDSG
ISAAPHMSCVGDSKAELRQLLHDYQALGIKRIVALRGDLPSGAGLASSELRYANELVEFI
RDETGDHFTLEVAAYPEMHPQASNFDIDVQNFVNKVKAGADSAITQYFFNADSYFHFVDR
VQAMGVDIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVDSIRQFGQHVI
TELCQRLLDGGAPGIHFYTLNQAEASLAVWQQLSHSAK
>A0A1I3SHL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomicrobium apsheronum|TrEMBL
MRIAQLLQRQEPFLSLEFFPPKDRAQWPGFFDVVRQLRDLGPLFCSVTYGAGGSTQHNTL
EIVTRMKQEYGLEPLAHLTCVGADRARIGSFLSGLAQAGVDNVLALRGDPPRGESTFTPD
SEEFQHGSDLVSFIRQDFSDLSIGVAGYPEKHPEAPNMDDDLERLRHKVACGADFIITQL
FFDNDAYFDFVARARAVGIGVPIIPGILPVQNLAALKRMLSFCGASVPGEYMSDLEHVHK
VYGESGVRGLGLGYAKNQIRNLLDRGAPGVHLYTLNKADTCLDIWKDFSRRDGLK
>X5VLT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSHC422A00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTIKRILNETALTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A2Z6AYE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio ferrophilus|TrEMBL
MRIRDLMQQSGKFISLEFFPPKDPKDWPAFFETVAALKAVDPLFVSVTYGAGGGTQDNTL
EIVRKLRHEQGLTPMAHLTCVGASAEKLHGFLGALEEAGVENVLALRGDPPQGQECWEPD
SEEFRHASDLVDFIGRHYPDMGVGVAGYPEGHPECSTFREDFEFLKFKLDAGADFAITQL
FFDNRFYWNFLERLSSMGVNKPVIPGVLPIMSLQSAKRILSFCGANIPGKLLLDLEAADA
EGGAKAAYKVGMDWAKSQVRGLLEGGAPGVHLYTLNRAEACLELVESLDPALLGR
>A0A3M9Z5Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. IPPAS B-1204|TrEMBL
MSNSSPAELAFPISRFQQAVEAKEFLITAEVMPPKGGDPTHMLQMAQLLKGRVHAMNITD
GSRAVLRMSSLAAAVLLRQHGLEPVCQMACRDRNVIGLQADLMGAQALGIQNILALTGDP
IKAGDHPTARGVFELESVRLLKLIDKLNRGVDFNDKPLPDGATALFAGAAVDPQCPSWSG
LQRRFERKVEAGAKFFQSQLISDFDRLEKFMDQIAASCNKPILAGIFLLKSAKNAQFINR
NVPGVQIPQDLIDRLERATDPLDEGVQIAAEQVKLARQLCQGVHIMAVRREDLIPQILDR
AGVAAVAG
>A0A7K7MLP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachypodius atriceps|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQPETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFFTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKTPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7C1PW06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Scalindua sp|TrEMBL
MDDNFKSGSNLEKLLKRGEFVVTSELGPPRGASREAVEKKAEILKGSADAFNITDCQTAM
VRLSSIASGVILINMGMEPVIQMTCRDRNRIAIQSDILGAAALGMKNLLCLTGDHQCFGD
HPDAKGVFDIDSIQLLDIVRQMRDEKRFQSGEELKVEPRLFLGAAANPFADPFKFRAIRL
AKKIAAGTDFIQTQIIYNIKKFEEWMSIVRDMGLHKKVFILAGVTPIRSLGMAKYMKNNV
PGMDVPDEIIKRLEGAEKKKVEGINICLEIIERLRKIEGVAGIHIMAIEWEEIVPEIVER
AGLLPRPNL
>A0A0G9JWB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter butzleri L348|TrEMBL
MFKTLIQKLQEDKYLTLETTPQHEPSMHNIIEKIKKFNLQDKIDGFSCTDNPLAKLRYNS
LFAALKLQQEFEKPVIATMTMRDRNKIALQSDLLGANDFDVRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGHPFKIEPKQIFPFAVVNSYAKNFSSLEKKMHLKI
QNGAIGIITQPIFDIENAQKLLESFDIAKENVEGDKRKSQLIFGIFPVTKLRTALFLSAQ
VPGIHVPQFWIDALEKAHSIGEEEEYKVGMELSSNLFKELNKLHPKIHLMTANRFDVANE
VIS
>A0A7Y2Q1I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium ulmi|TrEMBL
MTGKDVASLYDARHAIPAGTKVNVTFLGNEDLEMRVAAAKAVKDLGFVPVPHISARRLGS
RDALEEFLGRLQEIGATEHVFAVGGDPATPEGPYPDALSLIRSGLLERYGAREVSIAGYP
EGHPDIPTDVLWRHLDDKAAALRERGLDAVILTQFGFDVDPVASWIRSVRERGIHSQIRV
GTPGPAGIKRLLGFARRFGIGANAMIVRKYGFSLTNLMGTAGPDRFVSDLSALLAADPSA
GSVKLHFYTFGGLLATSEWARDHTAAHL
>A0A1T2XG24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus selenitireducens|TrEMBL
MQIDLRQALQQHILVGDGAMGTYLYNMGFPIGISYEELNLLHPDVIEDVHRQYVQAGAQL
IETNTFSANADKLSKYGLEGKVEEINRAGVRIARQAAGDSAYVVGAVGPIRAGRRKNISV
TFLQDCFEEQFKALLAEGVDGILLETFYEVEETQIALAKLRELSDVPVICQFAVEGGGRT
MDGYSLQDAFKVIEAAGADVIGFNCHTGPKGIMHSVESIQGHHNLPLSVFPNAGIPDYVD
GKYMYMTSPEYFGACAVEFANLGVRLIGGCCGTTPEHIHAMATALNGYVPNVNGGVSRDT
TSVRVTEPSLLDNHVSAAFTRRDTQPSIVELAKQRHTVIVELDPPRDLDITKFMKGAAAL
KEAKVDALTLADNSLAVTRMSNMALGYKVKVETGLRPLTHIACRDRNLIGTQSHLMGFDA
LGMDHILAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFIIG
AAFNPNVKYLDKAVQRLEKKIEAGADYIMTQPVYDPLLIERIYESTKHLNIPIFIGIMPL
ASGRNAEYLHNEVPGIQLSDEVRKRMAGLEGEAGRIIGTEIARELLDAAMPRFNGIYFMT
PFMFYEMSVNLAQYVWEKAAVSHSHL
>A0A6J5F2T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia solisilvae|TrEMBL
MNPNMNSIELSFEFFPPKTPEAVDKLRATRDQLMPLKPKFVSVTFGAGGSTQQGTLDTVV
EMAKSGLEAAPHLSCIGSSKDDLRAILNEYRSHGIRHIVALRGDLPSGMGAVGELRYASE
LVSFIRAEFGNTFHIEVAAYPECHPQSRSPRHDLENFARKVKAGADSAITQYFFNADAYF
HFVDDARKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVARRLEGFGDDRDAIRAF
GLDVVTALCERLVAAGVPGLHFYTLNGSAATKSICERLGL
>A0A2G7GLJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroococcales cyanobacterium IPPAS B-1203|TrEMBL
MLNNLNGTSLNSLRTAIIQGDFLITAEVAPPKGSNPAHMVQMAQQLKDRVHAVNITDGSR
AVLRMSSLAASVILLQYGIEPICQIACRDRNRIGLQADLMGAYALGIRNILALTGDPVKA
GDHVDAKSVFDLESIRLLKLIHKMNSGMDCCDQPLTDGATDLFPGAAVDPQLASWSGLQS
RFDRKLEAGAQFFQSQLITDFDRLEKFMDKIANGCGKPIMAGIFLLKSAKNAQFINRCVP
GVNIPQHIIDRLEQAQDPLQEGVKIAAEQVQIARELCQGVHMMAVKREDLIPQILDLAGV
APVKKEPVMSMTT
>A0A3E1HKL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GL93|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFSPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A4W3HD41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callorhinchus milii|TrEMBL
MMVKQRQHNGQLSKSGESCSDSSSRESSRSSTPSLESDRLREKMRRRIESGDKWFSLEFF
PPRTASGAVNLLSRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETL
LHITCCNQSKEQITEHLQKACRLGLKNVLALRGDPIADKWQTEEGGFNYASDLVKHIRNK
FDDYFDICVAGYPTGHPECTSYEEDLKHLKEKVEAGSDFIITQLFFKPQTFLKFLKDCRA
IGITCPILPGIFPIQGYHSLRQLVKLSKLQVPQEIKDIIEPIKDNDAAIRNCGIDLATDL
CKALLTSGAVPGLHFYTLNREVAATEILRRLGLWIEDPRRPLPWAVSANPKRKVEDVRPI
FWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSNSYITGESNRNGTKV
TCLPWNDESLAVETNLMKAELQKVNRRGILTINSQPNINAKSSTDPVVGWGPEGGYVFQK
AYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVKSENINNASDLQPNAVTWGIFPGREII
QPTVVDPISFMYWKDEAFALWIERWAKLYPEESPSRQIIQNIHDNYYLVNLVDNDFPLKN
CLWQVIEDMFLNSPLA
>B7G287|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeodactylum tricornutum (strain CCAP 1055/1)|TrEMBL
MVKIIEKIRDRRAKLRYRSNDSRQPSLHDCQLNFPGGNWYYSFEFFPPKTEAGLDNLLTR
IDRMAQRLDPLFIDVTWGSDKTSARTMALASHAQKYLGVDVLLHLSCQGMTRDQLIRVLD
QAKVLGIHNILALRGDPPKAKKHWQVGDVSGGECERAIDLVRLIRNTYGDYFGIAVAGHP
EGHPSSTSPEDELDHLKEKMRAGADFIISQFVYDTERFLDFCYRCRDVGIQCPILPGIMP
IQSYSSFTRMTQYCGVSVPDEIWKRLEPIKDDDEAVKEIGCSLAAEMCRQILADPIAKID
GVHFYTLNLERSATRILMQLDGTVNSGLVDKIRTKSGRILPWRPSAMTGRSKMEQVRPIN
WANRPKSYVLRTEDWDEFPNGRWGDSTSPAFGELSNFSHYYSFSLGSEDDQRNMLGSNPT
KSEDVYEVFALYIEGKIPHIPWCEATLQPESFLIQTKLAALNRAGFLTINSQPSVNAALS
THESFGWGGPGGYIYQKAYCECFCSPENMRCLVNMVKQNQSMNVYAVNNAGNCIQEGTEL
GGVTALTWGVFPNREILQPTIFDPRIFLVWAEEAFSLWTSMWSNLYDYDSDSFDLIETIR
DTYYLCAIIDNDYISESNRPSLWEGILNASQWQL
>A0A1H2RCC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter mobilis|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKDKLQVVRDRLAGVNPDFFSVTFGAGGSTRDRTVETV
LNLHKQGISTAPHLSCVGGTRESVAELLDLYKANGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDTFNIEVAAYPEFHPQARNAEDDLKNFARKVQAGANSAITQYFFNPDSY
FYFIDRLEKMNVTIPVVPGIMPIVNFSSLVRFSDMCGADIPRWIRKQLEAYGDDTDSIRK
FGEEVITDMCQKLLDAGVPGLHFYTLNQAEPSINIWQYLGISEREKIAF
>A0A0M4DRP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CFMR 7|TrEMBL
MALGTASTRTDHARTVRDMLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHRQS
>A0A2J8IF34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. AFG7.2|TrEMBL
MMFPIRIEIIPSEGIVEQVRALVPATTTLSVTCLPHHGIERTMRTAVELSDAGYTVIPHL
AARSIRSRAELTGIIRGCDAAGIREVFVIGGDRKQPAGEYESALPVLEDIAQYTSGLMRA
GVAGYPEGHPAVSPLDLLDSLLAKQHLASHVVTQMCFSAERIHDYAALLRREGVHLPVWA
GVAGSVPRAKLVALATQIGVGSSLKFLSRKGPLARKLLSGDRYSPDALVAGLESQPDSIA
GIHLYSFNSLDAVRSAAAASSPSALQTALIRGAARDN
>A0A4W3HDF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callorhinchus milii|TrEMBL
MMVKQRQHNGQLSKSGESCSDSSSRESSRSSTPSLESDRLREKMRRRIESGDKWFSLEFF
PPRTASGAVNLLSRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETL
LHITCCNQSKEQITEHLQKACRLGLKNVLALRGDPIADKWQTEEGGFNYASDLVKHIRNK
FDDYFDICVAGYPTGHPECTSYEEDLKHLKEKVEAGSDFIITQLFFKPQTFLKFLKDCRA
IGITCPILPGIFPIQGYHSLRQLVKLSKLQVPQEIKDIIEPIKDNDAAIRNCGIDLATDL
CKALLTSGAVPGLHFYTLNREVAATEILRRLGLWIEDPRRPLPWAVSANPKRKVEDVRPI
FWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSNCAKEELLKMWGEEL
VNEEHVFEVFTAYITGESNRNGTKVTCLPWNDESLAVETNLMKAELQKVNRRGILTINSQ
PNINAKSSTDPVVGWGPEGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVKS
ENINNASDLQPNAVTWGIFPGREIIQPTVVDPISFMYWKDILSPLTEGIMELS
>A0A428PHZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sp. AF-6|TrEMBL
MHIKEMLTDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRDQDK
WTAADGGFQYARDLVKHIRSTYGNHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKKVRERGVNVPILPGIMPIATYASFLRRANHMKAKIPQAWLDAL
EPVKNDDVAVRDIGKSLVAEMCRKLLANGIHHLHFYTMNLAQATRMVLEELNWAPSAERP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTVQDIAQLFVRYLRNEIDSLPWSESPLTSEADEIRDDLVE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPSNGYVYQKSYLELLVHPDVFNDMISRIEGHP
DLTFYAVTKDGELRSNAPSDCPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDASSPSRALIDEVMNEWYLVNIVNNDFHQNGTIFELLKGLEVKDLTTPATPKSEPE
ANGTEPVANGAAAA
>A0A2N1Y2B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium HGW-Gammaproteobacteria-2|TrEMBL
MKRYNRRQHGGVAMSAYVSVTFGAGGSTLSYTPETVRRLHDTFGLDATPHISCVGGSREE
IRTLLAQYRAQGCKRLVALRGDMPSGMARAGDFRYASELVGFIRAEHGDAFEVLVGCYPE
THPQADHAAADLAHFKLKVDAGADAAITQYFYNADAYFHFVDAARRLGIDIPILPGIMPI
VNFAQLRRFSEGCGAEIPRWVVKHMAAFGDDREAVREFATDLVAGMCQRLLAGGAPALHF
YTMNLARPTLAVLDRLQ
>A0A6I6N877|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces broussonetiae|TrEMBL
MKPVLAAAAVAGAALLDDFSLEMTGKDVSRLEEARGSIPPGTRINITFLAGEDLGMRLAA
ARAVKRLGFVPVPHISARLLPSRSALEEFLSGLAADGTAENVFVVGGDPARPEGPYEDSL
ALLRTGLLRRHGVRHVGISGYPEGHPAIADGTLWSALTDKATAIGAERFGGDVITQFGFD
VDPVLSWLEAARARGMHLPVRIGVPGPAGVRRLLGYATRFGVATSASVARKYGFSLTNLM
GTTGPDRFLHTLARRYDPERHGTVKVHFYTFGGLRHTAEWIAAFRQQDGPRESRA
>A0A811N444|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Miscanthus lutarioriparius|TrEMBL
MKVIEKIQEAAGNGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQSEEGATLEAYSNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMAGFCKTK
IPSEITAALDPIKDNEEAVKQYGIHLGTEMCKKILASGIKTLHLYTLNMDKSALGILMNL
GLIEEYKVSRPLPWRPATNVFRVKEDVRPIFWANRPKSYLKRTLGWDQYPHGRWGDSRNP
SYGALTDHQFTRPRGRGKKLQEEWAVPLKSVEDISERFTHFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGEKSDSTTVGWGGPGGYVYQKAYLEFFCAKEKLD
QLIEKIKAFPSLTYIAVNKDGESFSNIATNAVNAVTWGVFPGKEIIQPTVVDPTSFMVWK
DEAFEIWTRVWACLFPEGDSSRELLEKVQKSYYLVSLVDNDYVQGDLFAAFKI
>A0A2V4HNA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasma sp. Kam2015|TrEMBL
MLNRRKDMLSSSIKSIDFVKSVEIVPSRESGTEDLLKAADMLDGRVNALTCPENPRGSPG
IDPIMALYIISSERNIIPIPHITPRDKNRVYILSQIETAAKVGIRNFFTIGGDPINPKYE
SREVREIDVMEIMKLVKSRENTTVGAALNPYREVEQEIVGAKLKSGADFFISQAIYSPEY
LEKDWIRRRNFKLLAGFLPLTKKSQVKFSQNLGIMIPEEIRERLLNSDDIVSTSVRIITE
VFDEVKEYVDGIHIMPLGHNEVAAQILETI
>R5EA81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:590|TrEMBL
MNQATELREHIRQEIILMDGAMGTYYNRLHPETGEAEYANLEHPDWVKEIHKQYLYAGAQ
IIRTNTFAVNHMLFEQEQIKAALEAGVKCAREAVAEYRQESEDIMALIGASIGPIRYSDE
KEEMDVREEYKMIFRTMYDSGIRIFILETFDDWRIVKWIAEQIKTFADRQNEDVFVFAQF
SVNRSGFTKAGYSMQRLVTRLEQMESLDVFGFNCGIGAAHMNQLLQKLHFGKECILSALP
NAGYDHMLRGKQIYVDHPDYYGSMMRQILESGVNIVGGCCGTTPEYIKILAEEIQQNPIV
APKKIQKPVREDFREGKVNDFVEKLNQGQRVYVVEIDSPFNGKADKFLEAGFQLKENQVD
LITISDSPMARPRAESFEMGIYLANQTGARVMPHVCCRDRNVIALRSAILGGYINGIRDM
LVITGDPVARDDRGTVSGVFDFNSIKLMEYISNMNTEVFSEEPYFFGGALNYAGVNIEAI
VGRMKKKMEAGCSYFLTQPVYSDEDIERVRELKHRTGAKIILGLMPLVSYKNALFMKNEM
PGISVPNSIVNQYHPDMSREKAETIAEKVCVEIGKKAMDFADGYYLMTPFNRVTLVNRII
HDLRMSDR
>A0A3E0JZE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillaceae bacterium|TrEMBL
MGLLQDLQNHILIADGAMGTLLYSFGIDRCFDELNVSKPEEIERIHSAYLDAGATVIQTN
TYGANRIKLARYGLEDDIKIINQKGVELAKRALQKAENKGYVIGTIGGIRSFQKSAFTLS
DIAENFREQLHVLLSENVDGIILETYYDLEELKTVLQIARKETDLPIITNVSLHEQGVFQ
NGTRLADGLKMLEELGADIVGLNCRLGPYHMLQSLEEVPLFEHAFLSAFPNGSLPRYENG
RLVYESDEHYFYEAALQFRKQGVRLLGGCCGTAPKHIRAMAEAVSNLPPVTEKEVKERNV
PIHVLPMKESQETPLPDIAKNRRSVIVELDPPKTLGLEKFLTGAKALKKAGIDAITLADN
SLATPRISNVACANIVKSHFQLRPLVHLTCRDRNLIGIQSHLMGLHTLGLHDILAVTGDP
SKIGDFPGATSVYDLSSFDLISLIKQFNEGLSYSGKSLGQKTNFTVAAAFNPNVRHLDRA
VQRLEKKISCGADYFITQPLYSEKLIEEVYEATKHLNVPIYLGIMPLISSRNAEFIHNEV
PGIKLSDSIREQMQKAGNDKEKGKREGLAIAKSLIDAAFDLFNGIYLITPFLHYEMTVEL
TEYIHEKEKAKRERKISHV
>A0A1G6YU66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bhargavaea beijingensis|TrEMBL
MKLLDRLTSEVLVADGAMGTLLYSYGIDYCYEELNVTRPDAVANIHRDYVKAGADVIQTN
TYGAGLFKLGRYGLEGQMEEINRAAMRLAKGAAPEGRYVLGTIGGVRGIQSNGPALEEIV
ESTVRQAAVLLEGDPDGLLLETYYDLEELAAVVRRLRKLTELPIVAQVSLQEPENLQDGT
ALNDAFRLLESEGADVVGVNCRLGPFHTIRAFEQAELPERAFLSAAPNASLPALREGRFV
YSSGADYFGRSAVRLRNEGVRLIGGCCGTTPDHIREAKKQLEGLAPVTAKHVAPRIPQEI
READPLSREPIHEQAQKRRTVIVELDTPRHLETDAYFHAAQTLYEAGIDAVTLADNSLAS
PRISNLAMGSLLKHRHGVHPLIHITCRDRNLIGLQSHLMGLDALGIADILAITGDPAKVG
DFPGASNVYDVSSMELIRLIKGLNEGLSFSGKSLRKKTNFSVAAAFNPNVKVLSKAVRRL
EKKIEAGADYFITQPVYTKEKIIEIHEETKHLGIPIFIGIMPLTHIRNAEFLHNEVPGIQ
LSGEVLERMRACGEDRAAGAAEGVQIANELIDTAAKLFNGIYLITPFLRYEMTLDLFRHI
RQIDRRKESESYADITN
>A0A7X5US87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora amisosensis|TrEMBL
MTTQQEVAGPRGRRSQLAELVRNISYEVMPFKNTEQAVLSHVPTDVPLTVTVTEAKGIDT
TLRLTEKLLRHGYQVAPHLPARQFTGESHVAEVVDRLRSAGTRSVFVVGGDAPEPAGPYP
DAHSLLQAMEAVRHPFEQVGIGGYPEGHSIIPDESIELALKQKAPMATRILTQICFDANT
TASWAGRIAAAGIDLPVHVGIPGPVNRQKLVRISAGIGLGQSARFLRKQQNLLWRFLLPG
GYNPTRLAKRLAASAPKSGGNIRGLHIFTFNELRGTERWRQQLLASLSGKEDRS
>A0A6J3B294|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vicugna pacos|TrEMBL
MDRPKPRVPAVGPCCPSRGMRASEAGSARFSVPPCIRNSAMVNEPRGNGGPNPRSEGSSS
GSESSKESSRCSTPGLDPERHEKLKEKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRFD
RMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETVLHMTCCHQSREEITGH
LHKAKRLGLKNILALRGDPIGDQWEEEEGGFNYAADLVKHIRGEFGDYFDVCVAGYPKGH
PDAESFEADLTHLKEKVAAGADFIITQLFFEADTFFRFFKACSEMGIACPILPGIFPIQG
YHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCRELLESGLVPGLHFY
TLNREVATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGKELTSEESVFEVFVRYLSG
EPNQDGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGWG
PSGGYVFQKAYLEFFTSRETTEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGKLYEEESPSRMIIQHIHDNYFLVNL
VDNEFPLDNCLWQVVEDTFELLNRAPQNERETEAP
>A0A316V461|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meira miltonrushii|TrEMBL
MAIAPSTTPPLQTGVAHQRESSVDKSTSWKITTKIAKAQQEGRIWWSFEYFPPRTPQGLT
NLYDRIERMSGLGPEFVDITWNAGGRTSDLTAQLVKTVHTYMGLETCMHLTCTNMPRDKV
DTALKEAKKFGCRNILALRGDPPAGASEWEPHAAGFMYAKELVEYIREGYGDYFAIAVAG
FPEGHPEAKDGVDLEMKRLKDKIDAGADFIFTQMFYDYDIFARWVKDVRAAGIDVPIVPG
VMPIQNYGGYQRATARFRTIVPESFKQALDPIKEDDQKVREVGTQLVGDLCKKIIDPANG
LGISGLHIYTMNLERGSRMLLEYLNLQPSVQQVKQLPWTPSLTPKRRDEGIRPIFWANRA
KSYVDRTETWDEFPNGRWGDARSPAYGDVDAYGVKLRYTPEEGRELWGEPTDLEAVKELF
CNFCRGKVTALPWSETPIAKETTVIDEMLQKLNSLGFLTINSQPAVDGAPSDDPVHGWGP
KYGYVYQKAYLEFFCAPEKLDALITRIEADPRMTYHAVNAQGDMRTNTTSDSPNAVTWGC
FPHCEIIQPTIVETISFLAWKDEAYEIGRHWARVYSPDSPARKLLDEMFKSYVLVNVVHN
DFKDRHGIFQPFLDVSTKLNGSA
>A0A550JFC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas acetexigens|TrEMBL
MRVTDLWTKNARPTLSFEFFPPRSEKDEASFAKVVDTLAELKPDFVSVTFGAGGSSREGS
YQLVKKLIQEKELGVIAYLAAYGLGPDEICSILDTYADLGVENILALRGDPPRATEGLTP
HPESLAHASDLLHFIKGRYAFCLGGAGHPEGHPEAASKARDLDYLKLKVANGAEFIIANF
VYDTRLFFDFVERCRAIGIGVPILPGVMPIYSVKLLEILTKTCGATIGEEVRKGLAALPA
DDTKAVAEFGIAFAIKQCRELLEQGVPGIHLYTMDRSAAPLAIVNALKNEKLL
>A0A502DRS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium hodleri|TrEMBL
MTVSEPEVYTCPKRMTFGPCGGVRVDGQCEMRPGACTFADYVPWTGPDVTSEPVRAPLIL
TDFSCSPFDPADLAATAAVLACSCDAVLVGEHQNRPDFPPTLMSSLLLEGGVQPWITLSC
RDRNRVVLEQELRGLKHVGVQTVFCVTGDGRGYDVRPDVTQTFDLDGPRLVALAHELDMV
AAVPETLTAPPVGARPARLVQKQRAGASIAVLNHASSPALVEEFVNAARTAGLTIPVLAA
VAVFTDVVSAAVLQGLPGLELDQRIVDDVVNAADPVEAGIQAAVAEARALLSIEGVAGVN
VSGLASGAGTRVGAHVKAEVGARIRAAVAS
>A0A1H6VZT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter sp. SG02|TrEMBL
MTKVTEYISRAEGKALFSIEIIPPLKGQNINELLNSIEPLMEFNPPFVDVTYHREELIDR
VGPDGTIERIPIRKRPGTVGICARIMERFKVDAVPHVICGGFTKDETEDVLIDLHYLGID
NVLVLRGDPEKSAGVFRPKPGGHTYASELVTQVDNMNKGILLNAETQMSPTDFCIGVAGY
PEKHFDAASFDSDYAALKKKIELGANYIVTQMFFDNQKYFSFVERCRAEGITVPIIPGLK
PLSTKKQLTVLADIFHLEFPQELVKEVEKCATDKEVRQVGIEWGIQQCKELLAYGVPVLH
FYTMGKSDNVSQIARGVF
>A0A7V6L8R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKTAGQLIQELTKPGFSFELLPPMKGNSIKGVYRTIDQLKEFNPLFINITSHREEAVYRN
TENGLFERRVIRKRPGTVAVAASIQHKYGIKVIPHIICSGFTKSETEYALIDLNFLGIHD
LLLLRGDKPRRPDPLDVPSGEVNAHAIDLIGQVNNLNKGVFLDDTLAEAFETPFSYGVAG
YPEKHEEAPNLDSDIYWLKKKVEAGAEYVVTQMFFDNAKYYAFVERCRQVGINVPIIPGL
KPLTFLNQLTVLPRIFHVDIPEDFAKELRKCKNDEEATRVGVEWTTMQSKDLLANGVNLI
HFYTLMATNSVRQVASAIY
>A0A7V2HG07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacteraceae bacterium|TrEMBL
MRIGDLYKAGRPVFSFEFFPPKTDLAVEELLRTVRELKEVGRPDFVSVTYGAGGGTRART
VDCVRRIQNEVGIPSMAHLACMGHTEEEIAEVVGRLVESGISNILALRGDPPKNGEPARV
TSLRNATDLIRYLRTHFASIDLGGACYPETHPEAVSPEDDLMWSLRKQEYGASFLITQLF
FDNADYFRYVERARAVGVRVPIVPGIMPVTNVAQIERFTRMCGASIPAGLHARLERSRED
PGAVMAIGLEHAILQCRQLLAGGAPGLHFYTLNKSLATRVVLAALRSL
>A0A7X7X1C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MRVIDSIKNSNGPVFSFELLPPPKGKGIDSLYKSIDLLREFDPKYINITTHHSEYIFKEM
GNGTFERKTLRRRPGTVAVAAAIQNKYGISVVPHILCNGFTPEETEYVLIDLQFLGITNL
LLLRGDKDKSGVPTVGGYIHATDLEKQINDFNDGVFVDGSNMEMKETPFAYGVACYPEKH
EEAPNIDEDIYWLKKKVELGAQYAVTQLFYDNNKYFEFVDKVRKMGIDIPIIPGLKPMRK
LSQLTVIPRTFKVDLPEAFAREIMKCKTDEEVEIVGTEWCINQCKELIKFGVPGLHFYAL
GAANSVRAVARSIF
>A0A7Y7TWH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVIDHINESKSTLFSFELLPPLKGSTLQTIFDTINPLLEFNPAYINVTYHREEVVYRPS
SNGTLIPTVLRRRPGTVGIAAAIQHKYKIDIVPHIICGGFNQLETEDALIDLDFLGIHNV
LAIRGDADKIVGRFEPKIGGHRYAVDLVKQVIAMNHGNYQDETLEKPNPTKFCVGVAGYP
EKHGESPNSISDIQRLKEKVNAGADYIVTQMFFENKNYFNFVKACRDIGITVPIIPGLKP
VSLKEHLSILPKVFNVELPQDLVKEMEKCCDNRSVKEVGVKWAIEQAKELKKAGVPSLHF
YTMGKSDNIARIAKEVY
>A0A7X7YPP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVSELIRTATKTAFSFELLPPLKGNGIYRVFDTIDMLKEFDPKYINITTHHSETVYQED
ANGVIRKVNIRRRPGTVALAAAIQSRYGITAVPHIICKGFSKQETEYALIDLMFLGITNL
LLLRGDTNKLNEEQRKMDSHEHATDLQEQVNNFNKGIALDGTKFTPPEEPFSYGMACYPE
KHAESPNMESEIFYTKMKVDNGAEYLVTQMFFDNRKYFEFVDRCHAEGIHVPIIPGIKPI
HLKNQLTVLPKVFGTNIPEDLAKELRKCRNDDDAKEVGIEWCIAQCRELIQHNVPSIHFY
SFMATESVYRVAKEIY
>A0A7V0NGS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium|TrEMBL
FARRAHSAGINIVGGCCGTTPEHIRAMAEAVGGRRPRKRKIVPGIKVAEKPQPVRRYPRA
KTSLEKKISAGFVLTMELDPPRGIDASKLVQAARMFKELGGDAVNVSDLPMARMRMSALG
LASVIRLRAGIDIVLHFTARDRNLIAMQSDLLSAYAMGIDNILALRGDPPAVGDYPFATG
VFDISTFGLVKLISSFNEGRDLLGNPLDMPTSFFIGVGFNQNSNNFEHELERLEKKIQMG
AHFVQTQPMFDPAKIERLASHLRGRNIPIIVSIMPLISARNAEFLHNEVPGISIPTPIRE
KFERITSREKALEEGIAIARDMLSAAREIAQGACIMPQLGRYSVVERIIY
>A0A7Z2J5P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. ms-22|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSLDEIKR
SFREQLYILLNEEPDGLLLETYYDIEEAKAVLQIARKETTLPIVMNVSMHEQGVLQDGTP
LKDGLSELSALGADVVGMNCRLGPYHMIQALEGVPILENSYLSVYPNSSLPSFEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTMPQHISAMAEAVKDLAPITEKEVKVLKEEMIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKSAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIREIMAKAGEDKEKQRTEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKETNAHVNYH
>A0A8J7ADH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nodosilinea sp. LEGE 07298|TrEMBL
MGYRLRTAAQAGQFLVTAEVMPPKGGNPEHMLAMGQLLKGRVHAVNITDGSRAVMRMSSW
AAALLLQQQGVEAVCQVACRDRNRIALQADLMGAYALGVRNILALTGDPVKAGDHPEARG
VFDLESVRLLKLLDKLNCGVDSNDKPLTDGALDLFAGAAIDPQSTSWSGLQRRFETKVKS
GAQFFQSQMITDFDRLAKFMDQVASGYNRPVLAGIFLLKSAKNANFINRHVPGAHIPQAT
IDRLAAASDPLQEGVQIAAEQVQAARQVCQGVHLMAVRREDLIPQILGQGGVAPVDAALA
QG
>A0A7X9GPW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MTVSEILAKAKTSVFSIEILPPLKGNSIQNVYNIIDKLVEFDPKFINITTHHSEIMYKEL
PDGGIKKLDVRKRPGSVAIAAAIQNKYKITTVPHLICKGFSKEETEYALIDLDFLGVHNL
LVLRGDANKLQVGQLAPNRNENATDLQAQINQYNEGIDVNGDSFEKPQIPFAYGMACYPE
KHEESPNMEYELHYMKKKAKLGAEYFVTQMFYDNQKYFKFVDLCRQEGITQPIIPGLKPI
TMCRHLNLLPKVFNTTLPIPLSDALQQCKNDAEAKEVGVEWAIRQSKELIEKGAPSIHYY
SLMASESIRRIVKEVF
>A0A7X6T8B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKISEILTRKKTLSFEIFPPKREDETFTLISETIKQMDSWSPDFISVTYGALGNTLSNTT
KVARYIKENSKAEPLAHITCVASTTAKVDEVCSELKEYGVENLLTLRGDMPKNIVEGPIL
SDFKHASDLARYIGWKWNGVFSMAGACYPEKHPEAPNLSTDIEYMKIKQDSGMEFFNSQL
FFDNEVFYHFLLKARKAGITVPIIPGIMPVTNYAQLDRMIQITGCNVPIKLWNYFDRYKD
DKAALEEIGLIFTSYQILDLISNDVDGIHIYSMNKSGFINRLMENISYIATEFFK
>A0A8J3R1A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rugosimonospora africana|TrEMBL
MTSPSFDLICEIEPPTKPDLRRVRHQIGVLAPVAHSFLIPDNHIGRATVSSIAVAHEVAA
MGGRSIACLNSRDRNLLGFRRDMLTAAAYGVSEFLFVYGDKPTAGDRTSELTVRAMLDEA
RALTGDPAFEGIPAFRVGVAAGPRRLPSWKRAADFVFAQMSFSVDALLRWRDAAALDVPV
YAGVLVLPSAAMARRLAATIPDIEIPAELIERVEQDRRHGVDAACEQIERLRESGAFDGV
HLVPVARYREMALRLEGRL
>A0A4Y5YJK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella polaris|TrEMBL
MAFHHAQHAQSLNQSLSELNDINVSFEFFPPSTPAMEEILWNSVRRLEPLNPKFVSVTYG
ANSGVRDRTHSVIERIQKETNLVAAPHLTLVDASDEELVELAKHYWNSGVRDIVALRGDL
PDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDARNAQADLINLKKKIDAGANRAI
TQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVTNFKQTKRFADMTNVAIPHWLHRQFEG
LDDDPATRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A8PLM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiella grylli|TrEMBL
MQLCQKFNFSFEVFPPQTHRGLKNLYATRQELSKLKPNYFSITFGAGGAIQHQSLLVIKQ
FVKDGIAATPHISCVNMTYPRLYDLLMEYQQLGVKQLLVIQGDLPKEVPKLSEFNYANEL
ISAIRKITGNYFHIIVAAYPEFHPQAFSPRKDIENFKRKIEAGANSAITQFFFNSDAYFR
FIEACEKASIHIPIVPGITPIINYQKLIQFSTACGAEIPLWLRKHLAMLSNDPQSLQEVG
IEFVTKLCQHLLQNGVKEFHFYTLNRANPTYRIIENLHRYG
>C5PJM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccidioides posadasii (strain C735)|TrEMBL
MHVKEKLAHSEASGRPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPPREKES
WAPTEGGFRYAKDLVKYIREKYGNHFDIGVAGYPEGCEDEEDPETLMKHLKEKVDAGGTF
IITQMFYDVDIFLDWVKRCRENGIQVPILPGIMPISTYASFLRRSNWVKCKVPESWMEAL
EPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQATKMVLEELKLIPSYETP
LQKPLPWRQSLGLGRRDEDVRPIFWRHRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSIKDLSAIFIRFLEGGLDRLPWSESPITEETDDIKQDLID
LNNRGFLTINSQPAVNGMSSSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNP
DLTYYAINKNGELKTNTSDSPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRLGDDWA
KCHDARSPSRQLIQRVMDEWYLVNIVNNDFHKTHDIFDLFNDIVVKDLDVEATGIEEPTS
QPANTNPERQNGDAAQTKDISVATNGTSN
>A0A4Q6UU63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SCA2-2|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRTGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSEDWETDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A318L0C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. LBP4|TrEMBL
MSTQEHPLGISFEFFPPNTDAGRDKLMGVRDALAERRPRFFSVTYGAGGSTQDRTLHTVQ
AVRQSGITTAPHMSCIGSEKARLRDLLTRYREAGIDRLVALRGDLPSGMGGIGELRYANE
LVEFIRAETGDHFEIAVAAYPESHPQAPSFEKDLENFARKMKAGADFAVTQYFFSAEAYF
HFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIADF
GEEVVSRLCQRLLDGGAPGLHFYTLNQAKPTLRVLDNIGC
>A0A431TGB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax gossypii|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPQFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVCEQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVGFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
VRKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASIKAFGLDVV
TDLCARLQEGGAPALHFYTMNQSAATLAVLERLD
>A0A1B7NGQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopogon vinicolor AM-OR11-026|TrEMBL
MKISKKIEQSTKEGKIWWSFEYFPPRTAQGLQNLLDRIKRMTALGPEFIDITWNAGGRTS
DLTSHMVKTCQSSVGIETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPQGKDE
WEAVEGGFIHGIDLVKHIHNEYGDYFDIAVAGFPQYQLLPPEERELEMKYLKEKIDAGVN
FIFTQMFYDVEVFIEWVNAVRAAGITIPIVPGIAPIQTWNGFMKATSLANTKIPQYFLDA
LEPHKNNDEKVREIGTKLVAEMCRKILAADLGIKGLHFYTMNLEKGTTMLLEELNLMPRV
ETIKPLPWRQSLTPNRRQENIRPIFWANRAESYLSRTESWDEFPNGRFGDSRSPAYGELD
GYGIWLKQTKEEALKLWGEPKSFEEVASLFSRFCSGGLKALPWSDQPASSETSAIASQLA
KVNELGFLTINSQPAINGVRSDDPQFGWGPSNGYLYQKAYMEFFVGPQLLELLLAHIDRD
SNMTYYVINKQGDLRTNTHSEGPNALTWGVFPGKEIIQPTVVEALSFMAWKDEAYELGVK
WANIYEAGSPSRQLMMEIMGSSYLVNVVHNDFKNPEAIFEPFFKAGAEYQSQHPNGSAAP
NGLAN
>A0A2J8G847|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. AFG20|TrEMBL
MTNQLPVRLEIIPTDGIIPKVQAHVPAGSTLTVTCLPHHGVEATVRASVQLGQLGYEVIP
HLAARSIESRPQLAGMLRDCEAAGITEVFAIGGDAPEAAGPYGNSGRLMEDIADLTGGTM
AIGVAGYPEGHPKHNELQMLDALLEKQHLASNVVTQMCFSAPRIGWYAELLRREGVDLPV
WAGVAGAVPRAKLIALATKIGVGPSLKFLNRKGPLARRLLNAGSYSSRSLVSELAAAEPA
LAGIHLYTFNNVETQPAMNWSGGEGAKAS
>A0A0W0EWV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moniliophthora roreri|TrEMBL
MKITKKIEQCEKANKVWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTAEMVKTCQGMIGIETCMHLTCTNMPKEKVDIALREAKISGCRNVLALRGDPPMGKDD
WEAVEGGFVHGIDLVKHIRREYGDYFDIAVAGFPQHMLLPKEELDQEIQWLKEKIEAGVN
FIFTQMFYDVNIFIDWAKAIRDAGITIPIVPGIAPIQTWNGFMRATSLAKTVIPQHLMDA
LEPHKNDDEKVRAIGTKLVAEMCRTILNANLGIRGLHFYTMNLEKGTKMLLEELNLVPRV
ETLKPLPWRQSLTPSRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGEPTSFAEVADLFARFCSGTLPALPWSDQAPAGETSVISQQLA
RMNTLGFLTINSQPAVNGAKSDDKVFGWGPSNGYVYQKAYLEFFVQPALLSILLSHIERD
SNITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAYELGQQ
WAKIYDADSPSRKIISDLMDSCYLVNVVHNDFHDRDAIFRPFFKAGEEYLASSKGKTPMI
NGDAH
>A0A8C6UUI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neogobius melanostomus|TrEMBL
MINKQRVTPRYARRMVNQVQRGDGTLSSRSDSSAASASGGDSSKESSRCSTPVLDADRTD
RLRYKMRRRMESGDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPSGDPGS
DKETSSMMIASTAVNYCGLESVLHLTCCNQSKDNISRHLSKAKHLGLKNIMALRGDPVGS
DWEEEEEGFNYAVDLVKHIRSEFDDYFDICVAGYPTGHPEAHSYKEDLIYLKEKVAAGAD
FVITQLFFRAETFLKFEEDCRPSGSPCVCVQGYQSLRQLVKLSKLEVPEEITRVIEPIKD
NDAAIRNYGIHQALEMCRVLLDSGRVPGLHFYTLNREVATMEVLRQLGMWQEDPRRPMPW
AVSAHPKRKVEDVRPIFWGSRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLK
SKSSKDALLVFEVFTCYIAAQPNRKGHKVMCLPWNDEPLAPETNMLKDELEKVNTRGVLT
INSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIV
NVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYED
ESPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFELLQTGLDTGDVLGALNTGDG
GASGGR
>A0A3L6JF07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MLESGRFTVTGEVGPPHGADHSLVLDRTNLVKDYCDAINITDNVRGIPTMSSMVCARFVI
QAGAEPVMQMSARDRNRILFESELYGAYALGVRNVLFITGDHTILGSHPQAKMVYDLDSI
QALQLASHLMTGQDLAGDELEGVPAFYLGATLNPNADPMELQVWRVEKKRDAGAQFFQTQ
AIYDTSRLEQFMEQIEPFGVKVLAGLIPLKGPKMATFMNERIPGIKIPKSFIERLEQAGD
GLKGDEKREAVRSEGLKIAAETIKKVRGIRGISGIHIMAIGWEESIPELVRAAGLYPRPK
>A0A6L7F2E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides flavescens|TrEMBL
MRYKTSSVATVVRLLEHARYEVLPTPSIEEKVLAHVGKDVPLTVTASPGKGLEATLELTE
RLTVHGYTAVPHLAARMVRDRAELSDIAQRLTAQGIEAVFVPGGDADPPGDYPDALSLLE
EIAALGSPFSHVGIAGYPESHPTISDDLTVQSMWDKRRYATHVVSNLTFDPDVLVAWVAR
MRGRGVRLPLLLGIPGPVERTKLLSMATKIGVGESTKFLAKNKGLFARLAAPGGFTGERF
LEKVAPRLAAPEMQVEGLHVFTFNQVEATTAWRRDLLDQLN
>S9WEM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strigomonas culicis|TrEMBL
MAKHIKALLAEENPESEYVSFEFYPPRTEKGEEELMSTVVPAFATQSPIFFDVTWGAGGK
TSDTTMRLCKELQEKYPDTPVNMHITCTNMPKGLIKEGLDFAKANHITNIVALRGDPPAG
ETYQANPDGFQCALDLIKYIREQYGDYFCISAAGYPEGHPARLPEKGRIDPEAYREELAY
LKQKVDAGADLIITQLFYDADIFIHFVKECRAIGITVPILPGLLPVTSYPSLTRMVELCK
TYLPPDMQATLEELKEKPEELKAYGVRQVVELIRQIKAANIGCNHYHFYTINTTKQTFGA
LKEMGILKE
>A0A524DZ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MLLQARHLETYNLPISHLASLLENKEFVVTGEITPPHGSDANIVREHTAIVAEYCDAINI
TDNVRGIPTMSSMVCARLILEAGSEPIMQMSARDRNRILFESELYGAHALGVRNLMFITG
DHTLLGSHPEAKMVYDLDSVQALQIAKHLMGGTDLAGDELEGIPDFFIGATFNPYADPLE
MQVWRTEKKQSAGARFFQTQALYGLDRFEEFMSELEGLDAGILAGIIPLKGPRMATFMNK
RIPGIKIPESMISRLEKAGRGLKGAEKREAVRGEGLLIASETIDAVRKIRGVNGIHIMSV
GWESAIPELVKGAGLHPRPR
>A0A5P9HH15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. THAF10|TrEMBL
MGILDSLQQDNILIADGAMGTLLYSYGSDCCFEELNLSQPNQIYHIHQAYLNAGADIIQT
NTYAANYHKLERYGLQDQVKEINSAGVRLAKKAAADHKGAYVVGTIGGIRAIKPEAIPLE
EIKRTFREQLYCLLLEGVDGILLETFYDLEELETVLQIARKETKLPIISQVSLQEVGYLQ
NRVPITEAMNRLEALGADIVGLNCRLGPYHMISTLEEVSIPQTAFLSAYPNASLPSYVDG
KLEYDSDAAYFKETALAFRNQGVRLLGGCCGTTPAHIQAFSETLRDVPPVKEKQVKRRER
KIILPSKKKDVPTPLFEKAKKEQSIIVELDPPRKLNTDKFLQGAQALKDAGIDALTLADN
SLASPRVCNTALGSIVKSQIGIRPLIHITCRDRNLIGLQSHLMGLHQLGIHDVLAVTGDP
TKVGDFPGASSVYDVTSFGLINMIKQFNQGVSLSGKELGESTSFSVGAAFNPNVRVIDKA
VARLEKKIEAGADYFISQPVFSEEKLLEVYDATKHIDAPIYIGIMPLTSSRNANFLHHEV
PGIKLTQPVLDAMNSHQDHPERARQEGLTIAKGLLDTALTLFNGIYLITPFMRYELTVEL
ANYAKKQNLSHSARRIQNV
>A0A524FY56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MTGGLHLIVSRLKRIIDSGEFCVTGEIGPPRGADHNIVIERTRLIADFCDAVNITDNVRG
IPSMSSAVCAKYVIETGAEPIMQMSTRDRNRISIESELYGAYALGIRNILFITGDHTLLG
SHPEAKMVYDIDSIQALKLATHLMSGTDLAGDTLEGTPQFLLGSTFNPYADPLEMHAIRV
EKKRDAGAQFFQTQAIFDTNRLESFMDLVRDLNIKVLAGIIPLKGPKMAQFMNKRVPGIK
IPKDFITRLEAAGEGLKEEPKRTAMREEGLLIASETIQSIRSIKGINGIHLMGIGWEESI
PELVKRAGLYPRPKVV
>M1ZPE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum CFSAN001627|TrEMBL
MAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKNIIGEYNYAFELIEKIKANN
NFGVSGACYPEGHIECESLKQDIRELKRKVDAGAEHLISQLFFDNNIFYEFLSKTQQKNI
NVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKKAMEDAGIAYAVEQIVD
LVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDIAV
>F3AAB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 6_1_63FAA|TrEMBL
MKLSDAMREKMLLSFELFPPKTDKGMENLPGTIEHLCKYKPEYISCTYGAGGTNVGKNMD
VCKMIKDAGTIPVTHFTCIGNTAEGIKEQLQNYLDNGVDHMLALRGDLPFGWTGTGGDFA
YATDLVAYVRKEFGDKIEIAVAGSPEGHISCRSLEADIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRCAGITMPVDVGIMPILDQAATINMALSRNACVMPRELCEIISKNWIFPN
PFVQDPFDADVEGKKARFKEAGIEYTIRQIDEYRACGIDGIHLYALNKWKDVSEIIDRSG
LRTLV
>W1W723|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli DORA_A_5_14_21|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4V1AXR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus indolicus|TrEMBL
MSYAREIDLLNQSVADLNGKINVSFEFFPPKNEKMETMLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKTIQQETGIIAAPHLTGIDATPDELRTIAKDYWDSGIRHIVALRGDEP
PGYTKKPFYASDLVALLKDVADFEISVAAYPEVHPEAKSAQSDLLYLKQKIDAGASRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMSKMYQGL
DDDQTTRNLVGASIAMDMVKILSKEGVKDFHLYTLNRSELSYAICHTLGVRPE
>A0A515D792|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax sediminis|TrEMBL
MNPPSTLPVSFEFFPPKTPEGVEKLRVVRQALYAQKPEFCSVTYGAGGSTQEGTFATVRD
ILAEGVAAASHFSCIGATRASVREQLGQLRAMKVKRLVALRGDLPSGYGAGSEFHHASDL
VAFIRAETGHHFHIEVAAYPEMHPQAKSPQADLQAFATKVKAGADSAITQYFYSASAYLR
FMDETRKLGVDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIRAFG
LDVVTDLCMLLRGAGVPGLHFYTMNQSVATLEICRRLGL
>W1WL90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli DORA_A_5_14_21|TrEMBL
ALRGDLPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDA
GANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWM
AQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPG
L
>A0A0B8X3H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrio sp. ArHS|TrEMBL
MKVIEHIEKAQAPLFSYEIVPPPRGRSIKDIIEVVEALAPLNPPWIDVTSHSSTSYFQER
IDGTIQKKTLKKRPGTLGICGVIQNRFKIDTVAHILCLGFTREETEDALIELSFLGIENV
LALRGDTPNFQKQIRVDRTVNSYASGLVSQIKDLRDGKFLDDLDRADSLDFCVGVAGYPE
KHFEAACLKNDIQNLKKKVEAGADYIVTQMFFDNQKYFDFVTQCREAGITVPIIPGLKVL
KSANQLKTIPKNFYIDLPEELVDGLLESPQHAAEIGMNWCRKQVEGLLNFGVPAVHFYVL
NDVHSIVKVVKGFK
>A0A377JR22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter cinaedi|TrEMBL
MLEQLITKLKSNEPFLSVEVSPSLSSTIGQSVIDELESLKIADCFVCTDSPLARLKPSSI
LSSIKLQNALKKPVICTLSMRDRNSIALCGDILGVNEFGLRAFLSLSGDGVKNGDCVGAK
GVFEESSLKLGRIIDGLNQGIAANGKALKEGVKQIYNFSVINSYANNTESLKKKMLKKLS
NSAVQGLFTQPVFSLEAARFLLESMESINKDLGQNCVMILGFFPVLSYKVALFLRDKLPG
VYIPDEWVQKLEKASLKGKEVERKIGLELSRELFKDLQTLHNKFHFMSANKPSLLREFV
>A0A4Q2ABN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp. A46|TrEMBL
MTTPRISFEFFPPKTLEASFRLWDTIHTLAPLGPRFVSVTYGAGGTTRELTREAVGALHN
ATGLNVAAHLTCVDASRAETLAIADQFARGGVSEIVALRGDPPKGSNGFAPHPDGFADSC
ELISALADTGKFTIRVGAYPEKHPEAADQKADIDWLKRKIDAGATEAITQFFFEAETFLR
FRDACAAAGIDAPIIPGVLPVENWTGARKFAVSCGTQIPAWLDDAFAKAIRDDRHDLLAT
AIATELCSDLIEEGVEDLHFYTLNRPDLTRDVCHALGVTPRVELRDVA
>A0A318ZDJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus saccharolyticus JOP 1030-1|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKHHGDYFCIGVAAYPEGHPADNFQDSQDPARDVPYL
VEKTQAGADFIMTQLTYDIDAYTKFENMLRNHESGAFKTIPIIPGLMPLHSYKILTRVTK
LSHVKIPPQTLARLEEIKHDDDAVKRAGVDIVCDLVDGIRGIPTPGLRGFHFYTLNLEKT
VSFLLERCDLIGPYTEYDEPIEHSAAYSASRLETPARALASRRSSVSSMPHNRVIVDKLQ
PSDVSSRESVSHEATALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHISPAVAHKVWGYPVTREDISALFRRHVSGELYIVPWSEGGAEEGSG
TLNAETEIIRPELLQLIDKRGWWTLASQPAINGVRSDDPIFGWGPPGEGFVFQKPFVEFF
CPSKDYHTILKPLLERHGHEKLAWFATNVKGDFESSLPGSNVEDPDPIDINPANVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDATKNDVWLVCVV
GQEFGAGTEVGSKEEEEETKWMWRELAGC
>A0A2N0LEM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G4|TrEMBL
MIIKDILESTRTISCEFFPPKTADGMDAVFRAVDRLKVFRPDFVSVTYGAGGSTRGFTEE
IVTRIKTEAELEVMAHQTCVGQNKEDVHNSLARLEAAGIENVIALRGDLPQGDHADAPVK
SGFSHASDLIGHIRDNFEFGVAAACYPEGHTESVDLDSDIEHTKLRVNQGADFLITQLFY
DNKYFFDFVDRAIKSGINVPIIPGVLPILSTGQVRRFTTLCGAKIPPALDQQLEKFGEDD
DEVRELGVEYATRQVRELWDAGVPGVHFYVLNRSYSVSQILTSLGLKGHCVQPED
>A0A444IWF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electrothrix aarhusiensis|TrEMBL
MRTNTGVGPRGVDLLIIETFTRLDEMLLAIAVARKEAPDLPVIGQMVFPSRGMTVQGDDA
LSCGRAMIEAGAAMVGTNCGRGIDAMVSAIGRMSILAGEGIPLSAFPNAGMPEQVGHRMI
YPAQPGYMAIRAREMIRNGVHLIGGCCGTAPSHIQEFRSALKIKPVRVQAKNVEIREEIQ
EDILPEPRNGGFLESLQRGRLPIIAELDPPTHLDAEPVLAGAERLAEAGVDAISLGENPL
AILRAGNLGMASLIRQRTGIQTILHQTGRDLNALGLQSRMMEAHLLGIEAVLAVSGDSAA
GTDQPGVSGIFDLRSAGLIRMLDSMNRGMNMAGRPLKKQTNFSIGAAFSFRPASPGLQIR
RLEKKAALGARYAMTQPLFSVDEIEQMMEQVQHIDILIFPGIFPLISLRNAEFLHNEVPG
IYVPAELRKQLARFDKVADQRKVALEYTTELVEKISSFIDGLYLISPLNKWDIILDFVVQ
ARQAGWKGSGRVDQLCVAV
>R6MZF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium leptum CAG:27|TrEMBL
MNLDTLLKQKRPVITDGAMGTYFTQKTGFSIHECEWANISRPELISEIHREYVKAGAQFL
RTNTFSANTKSLGRPLADVLEIVRAGYRLAKEAAGCQAVAAADMTAIYPRGDEETDLLPE
YLAIADAFLSEGAEVFLFETLTELSPFDQIADYLKKKKPECKVLISFTVSPEGITRLGVP
LRRLLDEVKPHRELFDGIGLNCGCGPAHILKFARELLSYSRQYLSLPVLVMPNAGYPAME
ENRTVFDTSPEYFSHQAVRIAELGVDMIGGCCGTTPKHLQLLSRLIQKKREPLAAVTTTV
TAVGSLEKSAPRESRFAQKLRKGEFVMAAELDPPYGSRVDKLLTACRVLQNSGVDIVTIS
DSPMARVKLDPVVCGAKLQRETGMEVLPHFCCRDRNVNALRAMLLGAQCENIRTILAVTG
DHVPELDRGYIKPVFNVTSAKLMEMISQMNQDVFVDSPFTIGGAFNPNVANPKAELARLE
KKLKAGAVFFLTQPVFDEGRISTVKEARAMGAKMLLGIMPLVSYRNAVYMNNEVPGIQIP
TAYVNRFSPEMSREEAQRTGIEIALEIAESLRPHADGFYFMTPFNRAEIVAELIEKCREM
>A0A7R6HUU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae complex sp|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMFAADLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A524GGY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MPDGRRQLGLGHRVCGAGRYPGLLDCCGRGPSRLDGYRDRRAGLARRIFTGGSQRRPRGR
VRRNAGGAGRAVKAEDLRRRLADHVVVMDGAMGSELLQRLPEGARMDLAVHEHPQEVLDI
HLAYIEAGAELIETSSFGCSRPRLERAGAGDLTEKINAGSVKLAREAREISGRDILIGGS
IAPLAGVLDLDEPEGRAMIPLAHAEQASILAGRGADLLILETFFRIDELAIAVAAVRSVT
DLPLIGMMTFAHERAPHPYKEQAEFLDKLAELDLVAVGVNCSPGPMGTLEILRQVTQLRV
PLAASPNAGTLVRREGRILMPPATPVYLAQFVRQAVGLGAAVVGGCCGTGPEHIRAIADA
VRDLAPQPRTTTVVAVGPSPPVPEAIRPSSALAAKLERGRFVRLVQLDPPKGTNVEALLE
ASAAIAGHPDVDGVDINSNPLARLRMDPLYLGQLIQQRTGLETVPHITPRDASLMGLQSQ
LLGAWRGGIRNLLAITGDPSQLGDYPGVHDVYHVDIFELVRSLSRLAEGYDCAGNRIGDP
PGFLVGVAVNPAADDPQKEADRLRRTFDNGAHFAMSQVTFDWRAWDRFTGLFGGELPIPT
LAAVWPLRSLKMAMRLHYEVPGIVVSEDLLRDLDAAGADAEKIGYEWAVKMLRQAPDHAA
GAYLIAPFKQPQAILPLI
>A0A6P0XJJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO2D1|TrEMBL
MNRFRNAVKSGEFLVTAEVAPPKGADPTHMIEMASTLKGRVHAVNVTDGSRAVLRMSSLA
ASIILKNNGIEPICQVACRDRNRIGLQADLMGASALGLNNILALTGDPVKAGDHKKARSV
FDMESVRL
>A0A6F9ZKM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidaceae bacterium|TrEMBL
MALPATGLERVTSEMQQACVRIFSLQRARALETVQQFAVASYVIRIVFCNFTPQYSIIPK
MKITELIAREPGTAFSFEVLPPLKGAGIGGLKRTIDSLREFDPKYINITTHRSEYVYKDL
GGGLMQRSRLRRRPGTVAVAAAIQNEYHIPVVPHILCSGFTREETEYVLLDLQFLGIENL
LVLRGDKAKEDSHFKPTPDGYAHTTELQEQINRFNAGEFVDGTPVKEPGRPFSYGVACYP
EKHEEALNLDTDFAWFRRKVELGADYGVTQLFYDNTAYFRFLDRVREAGLDVPVIPGIKP
FTKLSQLQTVPKTFHCDFPPELAEEALKCRTDEQARQLGIEWTVAQCRELMSRGVPSIHF
YTVGATDSIAEIARRIY
>A0A7Z8S5P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. BF9-10|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRIYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVKPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A3S3RPU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electrothrix aarhusiensis|TrEMBL
MKSGSNLERVLRSGAFAVTGELGPPKNSDPDVVREKARILKGNVDAVNITDCQTAIVRMS
SIGAGLLAQAEGVEPVIQMTCRDRNRIGMQSDLLAASALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMIRDMRDGKKFQCGEEIKGKTTDMFLGAAANPFAYPHEFRAVRMGKK
IANGADFIQTQIIYNLDRFAEFMKKACELGLHEKAIFLLALLHPSRWEWHAT
>A0A094GJ75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-103|TrEMBL
MADSPTTDKITDKIAALRQDASYFSLEFFPPKTAMGSTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSKALVDDALKAAKEAGIQNILALRGD
EPRGEYKDALEEGKEGEDEFVWAIDLVKYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
EHDLPYLVDKVQAGADFIMTQLFYDVDAYDNFEKVLRDHSSGAFKSIPIIPGLMPIQSYQ
ILRRTTKLSNAKLPESIIDRLDAVRTDDEMVKKVGVDILAEIVESVKATKQRTKGPKGFH
FYTLNLEKAVAFILERVNLIPSFTPVLTSDAFAVDDITDTIPLPQLLINGERKNRRQSSV
GSGPHNFVIIDREEASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRPDITSIFVQYLNGTLSALPWSDE
PIAAEANLIKDELVKLNQKGWWTIASQPAVNGARSQDEVVGWGPKGGWVFQKAFVELFVP
TSDWARLKPLLEGNGEVSFLAQSASGEFLKSKLDLGPGEEGSETNAVTWGVFPGKEIVSP
TIVEEVSFRAWAEEAWQMWEEWAAVFGKSGEESRRFLDGVAKDGWLVNVIWHDFVGMCKA
KEGRSEEEGYKGLWDVLIEA
>A0A416NB84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF23-8|TrEMBL
MIQEKEHKGVVFSCEVFPPKRDDDIYQIYKTLDEIKTLKPDFISVTYGAGGSNSKKTATI
AAYIQNICEVEALAHMTAVGMDEASLRALLFELKKKGVENILALRGDKPRTMSQEEFDQR
YFKYATDLIPEIKKNGDFFIAGACYPEVHPESKNQEEDIQHLKQKVDLGLNCLITQMFFD
NNAFYSFMDKLEKAGIDIPVHAGIMPVTAAKQLGTSVTLSGSSVPVEMSNMIAKYGENPE
DMKKAGIEYAVNQILDLKKHGVAGVHIYSMNKADVTKQIYEASF
>A0A0F5Q1G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia psychrophila|TrEMBL
MLDDNLRASRLTADQRPELQISFEFFPPKTDVMEEKFWDSVHKLAPLKPRFVSVTYGAGG
STRERTLRMVSRIKSETGVDAAAHLTCVGATRDEVDAVVRGYQDAGVTRIVALRGDPPEG
VGQPFTPHPEGYRNAADLVGGLRRIGEFDISVAAYPEKHPQSADWQTEIDNLKRKIDAGA
DRAITQMFFTNGDYLRYVERARAAGITAPIVPGIQPIHNFKQIASFASRCGTSIPDWLAE
RFDGLDDEPETHALVASAVAAEQVTELLDEGVTEFHIYTHNRSPLALALARILGRRPEQ
>A0A416LF75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF25-28AC|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNVLCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A4Q4A8X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMFAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A091E8U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fukomys damarensis|TrEMBL
MDHGKARVLAAGPRCPSLGMWASKASISRYSVPTPISRTWAMVNEARGSGGGSSDSEGSK
DSSRCSTPGLDPERHERLREKMRRRMESGDKWFSLEFFPPRTAEGAANLISMFDQMAGGG
PLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETMLHMTCCQQSPEQITGHLYKAKQ
LGIKNILALRGDPIGDQWEAEEGGFDHATDLVKHIRGEFGDYFDICVAGYPKGHPEAGSF
EEDLRHLKEKVSAGADFIITQLFFEADTFFHFLKACSEIGISCPILPGIFPIQSYSSLRQ
LVKLSKLEVPQEIKDVIEPIKDNDAAICNYGIELAVSLCQELLASGSVPGLHFYTLNRKM
ATTSVLKRLGMWTEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQDWNEFPNG
RWGNSSSPAFGELKNYYLFYLKSKSPRQELLKMWGEELSSEESVFEVFAHYLSGEPNQYG
YKVTCLPWNDEPLAAETNLMKQQLLRVNRLGILTINSQPNVNGRPSSDPIVGWGPSGGYV
FQKAYLEFFTSRETVEALLQVLRKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGR
EIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSRMIIQYIHDNYFLVNLVDNEFP
QDSCLWQVVEDAFELLNRPAGLVREVEAS
>A0A1Q9T7S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. CNS-139|TrEMBL
MRPSNADAVVRELVATASIEIIPMKGSDLAFDLVPAGSTLTVTCSSKFGLERTLAYTEAA
RLAGFTAVPHIAARQVSGRSELAELLRRLAEAGVDNVYVIGGDADTPRGEYASAAELLAD
LAGLDHGLREIGVACYPEGHPAIPDDVLFDDLCRKQPLATYMVSQMCFDVDAIVRWLGGV
RARGIALPLRLGVAAPISVRRLAELSVRIGVGSSLRYLSKQHSMVRNLVLGGAYRPEQLL
GRIATDPAYPDLGIGGVHLFSFNQVAATVDWQQRIAAAA
>A0A2M6ZKQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG07_land_8_20_14_0_80_60_11|TrEMBL
MSVTTPSKLQKMIASGNLAVTSEVGPPRSADGAVIEHKGNLIKDYVDAINVTDNQTSVCR
VCSLACCIRLKLMGLEPVLQMVTRDRNRIALQSDILGAASFGINNMLCLTGDHQHFGDHP
TCANVFDLDSIQLIQTVKMMRDEGRLLGGFEFAVRPQMFIGAAANPFAGPNVAMRVSRLA
KKVAAGVQFIQTQCIYNLDKFKEFMKLMVDRGLHEKVAILAGITPLKNVGMAKYMQKRVP
GLEVPDSVVRRIGGVPKEKQAEEGITLAVEQIQELKEVEGVRGFHIMAIEWEEKVPGIID
RAGLYPRPQLA
>A0A4R7FDZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amnibacterium kyonggiense|TrEMBL
MATIGTTNESAARLLAGCSLEMTGKDVPALVEAEGLIPAGTRVNVTFLGNEDLETRVAAV
RAVLERSLLPVPHLSARRLRSAAELDEYLGRLAEVGGAERVFVVGGDPAAAEGPFDSALD
VVRSGALGAHGVREVGVTGYPEGHPDIAEDVLWAALRDKVSEIGAQGLQASVITQFAFDA
DAVVSWIRRARTEGVNAPVRVGVPGPAGVKRLLGFARRFGVRSNATIVRKYGFSLTNLMG
SAGPDAFVDDLAARLEAEPGLGEVGLHLYTFGGVATSARWVAERRGATGGDAR
>A0A7J4KMT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
NVTDNQTAVVRMSSFAGSVLILQMEMEPIMQMTCRDRNRISLQSDVLGATALGVRNILCL
TGDHQSFGNHPAAKGVFDVDSLQLLQIIQKMRDEGIFQSGDSLLGIRPCVFLGAAANPYA
DPFEIQVDRVRKKIDAGAHFIQTQSVYNIEKFSEWMDDVCSQGLDKKVHIIAGVTPLKSV
KMAERMKFHVPGTDVPDFVYERMKNASDPAKEGYQIALKTIRELKQLKGIHGIHITALFW
EEIIPSLVKESGLQSPR
>A0A1Y4W380|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilimicrobiota sp. An105|TrEMBL
MKISEILKKKATISFEVFPPKNKEGDISSIYYTIEELSQLNPDFISVTYGAGGSTKGKTV
EIASTIKNQYNIEAVAHLTCISSTESEILDICQQLKDNHIENILSLRGDYPQDGLQHELS
FHYAKELNTFISQHFPGDFCLSGACYPEVHQEASCLEDDLKALKEKVDAGAQYLITQIFF
DNHYYYRLVKEARKRGINVPILAGIMPVTHSKSLLRTAKLCGCSIPYELSTMIESYYHYP
EAMKEIGINYATHQIIDLITNGVDGIHIYTMNKPEIAKAIFQSIPTVLKELNHE
>A0A7C1S7G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leeuwenhoekiella sp|TrEMBL
MKVTEHIKQAQGKTLFSFEIIPPKKGSSIQELYNNIDPLMEFKPPFIDVTTSREEYVYIE
RDGLLDKKITRMRPGTLGICAAIAHKYNVDTVPHVLCGGFTKEETEYLMIDCHYLGLDNV
MALRGDAMKEQQYFEPTKGGHDYALGLVKQLKDMNCGQYLNDTVESKNCSDFCIGVAGYP
EKHLEAPSLKTDLKRLKEKVDAGAHYVVTQMFFDNQKYFEFVKLARAEGITVPIIPGIKP
LAVERHLQLLPQVFKLDLPQPLIEAVEGCTSNKEVREVGVEFCIQQSKELMEFGVPVLHY
YSMGKSDNIKAIASALF
>A0A7Y6LZH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CAI-21|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVTAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A7G7MGA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. CGMCC 4.1532|TrEMBL
MKITDRIGGDRPVFSVEFMPPKDEVGEAELWKAIRRLEPLDPAFASVTYGAGGSSRDRTV
RTTGRIASETTLVAMAHLTAVSHSVAELRHVIAEYAAAGIRNILAVRGDPPGDPLGEWVA
HPDGLTYADELVTLTRRLGDFCVGVAAFPYGHPRSPDEDSDLERLIAKVRAGADFAITQL
FLEPEGFLRLRDRLAAAGCDVPMLPGIMPLTTVRTLHRGPELSGAPLPPGLAERLERYAD
DPAAFRAAGMDLTTELCERLLAEGVGGLHFYTFNRSTATSELVSRLDLGARRGVPVA
>A0A7K3AVZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8378|TrEMBL
MALGTASTRTDHARTVREMLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A8J7LM36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingopyxis sp. YJ-S2-01|TrEMBL
MTLSVAQLNEAQFATGEPLFAGLPGDAEISFEFFPPKSEKMEEKLWDSILTLAPLEPRFV
SVTYGAGGSTRERTHKTVARIIRETGLPAAAHLTCVEASKAEIREVAEQYWEAGVRHIVA
LRGDPPSEGAKFVPHPEGYASAAELVKGLKEIADFEISVAAYPETHPEADCPDSDLDNLK
RKLDAGASRAITQFFFQSDSFFRFRDACAAHGIDQEIVPGILPVSNVAQTRKFAGMCGAE
IPDWMNRLFDGLDDMPDARQLVAATVAAEMCRRLYAGGVRQFHFYTLNRAELAYAICHLL
GKRPADHASKEKAA
>A9WAC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)|TrEMBL
MHSTLQRRLAAGQIVVTGEIAPPKGAARSHLEALARNIRDYVDAVNLTDNQRGIARMSSL
GGSVILQQLGIEPIMQMTCQHRNRIALQADALSAAALGVRNLLAMTGDHPRIGDHPEAKN
VLDLNSFQLIRVLRTLRDQATFQSGTPLKEAPRFFIGSVANPNVERAARLEKKIEAGAEF
VQTQLIFDVGRFRQWMADVRAAGLHQQAYILAGVMILRRPHSAIYLRDHLPGTLMPETVI
ERMQRATDSEAEGITLAAELVNELLSVEGVAGVHIMSVDWTRAIPRVVEQAGLLPRPPVP
STEENVL
>A0A7X5AKN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas icarae|TrEMBL
MSTQQHPLGISFEFFPPNTAAGREKLVGVRDALAERGPRFFSVTYGAGGSTQDRTLTTVR
QVREAGITTAPHLSCIGSEKGQLRELLARYREEGIDSLVALRGDLPSGMGGVGEFRYANE
LVEFIREESGDHFEIAVAAYPESHPQAPSLEQDVENFARKVKAGANLAITQYFFNADAYF
HFVERAQALGVDTPIIPGIMPITNYTKLARFSDACGAEIPRWMRKQLEAYGDDSESIAAF
GEEVISRLCQRLLDGGAPGLHFYTLNQAAPCLKIVDNIVG
>A0A2K3QEY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolypocladium capitatum|TrEMBL
MDKITDKIAALPADAEYFSLEFFPPKTAMGFANLRHRLRRMEQALRPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRRLIDKALEDAKVLGIRNILALRGDPPRHDE
YRNSEDSEDDGSEDFTWAIDLVRYIRRNHGDYFCIGVAAYPEGHADESHPLGQSLEHDLP
YLVDKLQAGADFIMTQLFFDIDAYEKFEKTLREHPSGAFKTVPIIPGLMPIQSYQMIKRT
TKLSHAKVPAAILSRLNDVKGDDEKVKMVGVDIVSELIERVRAIKSQRPGRKGFHFYTLN
LEKAVAFIVERTGLIPDTSEDDEAVIDEAAPPPPMLQVNGNLFLRARSHSRTSRRQSSVG
SDPHNRVIVGSRHPAHPEWEATGQEAGIPAESINSRANTLAISEGEGALGREATWDDFPN
GRFGDSRSPAYGEIDGYGVSLHVSVAQAVRLWGHPKTGADINDIFVKHIQGQLSAIPWSE
EELMPESSTIKARLIDLNNKGWWTVASQPAANGVPSGDSTFGWGPTNGFVFQKSFVEFFI
PSSDWETLSDKLNAPEVRDVVCFFAASAKGDFASSDSSGGANSASPEASTNAVTWGVFPG
KEIVTPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSDSEKLLSGIKEDYWLVNIIHHDFV
DRDALWGLLMA
>A0A3M2HJY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
HKVDQGAHYIITQMFFDFQVYKNFVERAREIGITVPIIPGIKPLTTLEQLSFIPRYFHVN
IPYPIVEAMENARTREQIRKVGLEKTAELCRQLIDYKVPGLHIYTMGRGSATRDLLKMLM
G
>A0A1I7JP79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus koppenhoeferi|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPSTAEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKEKTGLDAAPHLTCIDANREELRTIAHDYWQSGIRHIVALRGD
LPNNGCKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATMTNVRIPSWMTRMFE
GLDDDPESRNLVGASISMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPA
>A0A350LV92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp|TrEMBL
MTGPYPDPPAFVSFELFPPKTDAGEATLTRVVDQLASAEPAYFSVTYGAGGSTRDRTARV
VDMVRDRTGRPVAHHLTCVGASRGEIDRLARGLHEEGVSRIVALRGDLPEGQRLAPDGYG
DAAELVAGLRRVADFDISVAAYPEVHPEAASVAADLDHLKRKLDAGAARAITQYTFDTEV
ILRFVDRARAAGITAPIVPGIMPVTNFAGLKRFSAMCGATVPDWLARMFEGLDDAPETRA
MVATSVTTEQCRLLMEAGLSEFHFYTLNRPEVSLAVCRALGITPAIPSESAA
>G0EQI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira intermedia (strain ATCC 51140 / PWS/A)|TrEMBL
MNNNSSNVENFITKLENRDEYTFTLEISPQAKYDLGYIEEKINNSNISNYIDGFVVTDSP
FANLKISSILAALQLHQRLNNNKPFIATQTMRDKNSIALQNDLIGANYFDIRMILAVTGD
PINGGNQKQAKSVFEGNSELLIAIIKDLNKGKSLGEFTFKEPLKHIYPFCVINSYAKNND
NLKVRLAKKANSGVKAIFTQPIYEAERLELLLKWIDELPLKNKPVLVPGFFPILTYKTAY
FIYYKLPGAYIPETWLHKLKKASDKSPEEEKKVAVELSSDLFHSMLKKHKKMHIMSMNNY
DFVVDLLKTIK
>A0A0T7BXK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix sp. 336/3|TrEMBL
MHENHSPLPISSFRSAALAGNFLITAEVAPPKGSDVSHMLQMAATLKGRVHAVNVTDGSR
AVLRMSSLVASAILLHQGIEPICQIACRDRNRIGIQADLMGAHALGIHNILALTGDPVKA
GDHPQAKPVFDLEAVRLLQLIQKLNQGVDDNEKPLPDGATDLFTGAAVDPQCPSWSGLQS
RFEKKLAAGAQFFQSQLITDFDRLDKFMNTIAAGCNKPILAGIFLLKSAKNAEFINRCVP
GVQIPQHIIDRLAQAKDPLEEGMKIAAEQVKIAQQLCQGVHMMAVRREDLIPEILEMAGV
GLTSSRLTSPSVPEERIQLIGN
>A0A0B0ENG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Scalindua brodae|TrEMBL
MSEEHNTNNNFKSGSNLEKLLKKGEFVVTSELGPPRGASRQAVEKKAELLKGYADAFNLT
DCQTAMVRLSSIASGAILLDMGMEPVVQLTCRDRNRIAMQSDILGAAALGMKNLLCLTGD
HQCFGDHPEAKGVFDLDSINQLDMFRQMRDEKKFQSGEELKTEGPKLFLGAAENPFADPF
QYRAARLAKKVKAGADFIQTQIIYNVEKFEEWMGMVRAMGLHKKVSILAGVTPIRSLGMA
KYMKKNVPGMDVPDELIKRLEGAEKKKAEGINICLEVIERVREIEGVSGVHIMAVEWEEI
VPEITERAGLLPRPTL
>A0A2N0VLK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodohalobacter barkolensis|TrEMBL
MKVIEHYKKATEPLISFEIIPPRRGGGVNSIFDSLDRIVEKVKPPFIDVTYHAAEAYVEE
LSDGTLKRIIRRKRPGTIGLCAAILHRYDIDPVPHLICEGFTKEESEDALIELNYLGIHN
VLAVRGDNTGSQVPMHTNGTANKYAIDLVRQIQDMNRGEYLEDIVNAQQTDFCIGVAGYP
EKHFEAPNIDWDVQRLKEKVDAGAHYIVTQMFFDNSVYFNFVEKCRANGIEVPIIPGLKI
LRTINHLKTLPRHFHLNLPDELTKEVDANPDRVEEIGVEWAQKQSLELMEKGAPGIHYYI
MGNPKPALDVIDFIQKK
>A0A7R7T7N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kaistia sp. 32K|TrEMBL
MRETIDRASRNGAGASGLKVSFEFFPPKTEAMEQTLWSSIERLAPLSPSFVSVTYGAGGS
TRERTHATVSRILTETALKPAAHLTCVGASKAEIDAVVDAYAATGVRHIVGLRGDPVEGI
GAVYQPHPEGYAQASDLVSAIRTRHPEIEVSVSAYAERHPESRDWQTEIDNLKRKVDAGA
TRAITQFFFDNDLYSAFLDRVAAAGIDIPIVPGIVPVQNFTQTAKFAEKAGASIPAWFAA
RFEGLEDDASTRQLVAAAVCAEQVLDLVDRGVNEFHFYTMNRADLVYAICHLLGMRPVTV
EGSEAKVAVA
>A0A7J5BUD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoclavibacter chungangensis|TrEMBL
MTPPYAGAAARVDPDGAQRIPFSFELFPPRNADVAARMPDIVARLAALRPEFISVTFGAG
GSSRSTSLDLLRRIRTTTDITPLAHLTCVGSSYAEATGIIREFLDEGITNFLALRGDPPA
GLGEDDEFLGDLRTGAELVQLIHRVRREHVSVTPSLAAGHEEPRWRVGGRPGATVCVAAY
PNGHPRSRSIRQDYDALLAKEAAGANLAFTQLFFHADDYLRFVEGARTAGVTMPIVPGLL
AVTSTARLRRMAELAGEPIPVGLYRSLERARSVGARREVGIAHATALALDLLDGGAPGIH
LYTQNRIDEPTELLARIGAIERGGAGLHADRMPAGTLSRA
>A0A6P0YSH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Merismopedia sp. SIO2A8|TrEMBL
MSQSISANISPPPPSFSRLCQAARNQEFIVTAEVMPPKGGNPSHMLEMAEKLRNRVHAVN
ITDGSRAVLRMSSLASAVLLQQNGIEAVCQMTCRDRNRIALQADLMGAHGLGVRNILALT
GDPVKAGDHPKAKAVFDLESTRLLRLIHDMNNGLDSNGTPLPDEPTDLFAGAAVDPQSKS
WSGLQRRFERKIESGAQFFQSQLISDFEKLEKFMDGIASSAGKPVLAGIFLLKSAKNARF
INRCVPGVDIPDTLINRLEQAENPLQEGVKIAAEQVQLARQLCQGVHLMAIRREDLIPEI
LDLAGVETIE
>A0A842XF78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon|TrEMBL
MFILVKYSIEITQDNVRKNYAGYLDLAEFITIPDNPFGKAGPASVPMAYLVGKKYNKRTV
ATINTRDRNRVGTISEILAALELDLYGIFVVAGDTLKRGREVREIDVYQLISLIKKYRQE
YGSDILIGATLNPSRENELRIVRKKIESGADFFITQSIYDENIILNNRWIRHLSIPVYGG
FMPLLSKRIISFYSKSFSISREMVEVFIRSSNLLEDNVALFKRIIKSTCDTFEGYHIMPM
GNENFIERISRVIRIC
>A0A1E7DPW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Domibacillus iocasae|TrEMBL
MTLLDKLKTDVLTADGAMGTLLYSYGIDFCYEELNTEKPEIIEKIHHDYIKAGADVIQTN
TYGANTLKLSRYGIENRVRELNEAAIRIAKKAAAPGSQFVLGTIGGIRGIRKSTATNDEI
LASVREQAESLLAGDPDGLLLETYYDFEELSSSVQLLRQMTDVPIIAQVSMHEPGVLQNG
LSLNNALHQLEEIGADVVGVNCRLGPYHTIQAFEDVTLPNKAFLSAYPNASLLDVEDGRI
IYESEADYFGRAAVLLRNEGVRLIGGCCGTTPKHIEAAKKRLTGLPPLTEKKVKIKKPIV
IQEAAPATDVSICEKAKTERTVIVELDTPKTLMTEKFIEGANALYATGVDAVTMADNSLA
SPRVSNMAMGATLKMKHDVRSLVHITCRDRNLIGLQSHLMGLDALGLHDVLAITGDPTKV
GDFPGATSVYDVSSLELIQLIKQLNEGISFSGKPLKKKANFSIAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVFTKEKIIEVYEATKHLSTPIFIGIMPLTNIRNAEFLHHEVPGI
KLSDETLERMRACGEDKEASAKEGVKIAKELIDTAAGLFNGLYIITPFLRYDMSVELIHY
IKELDAQKESGALHDHTSN
>A0A7W8H2Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MAMSQAIHLRDQSDVLDDFSVEVTTKDTAQLAAMSGAIPKGTIISIPFLSTESDADRIRA
AKMVRQAGYVPLPHIAARRLGSESMLSAMLSALVNDAQVSRLLLVAGDADPPKGPFLDTA
TILRSGILEQHGISNVSIAGHPEGHPVQNAAMLTSALLEKRLIMEAANIEWSIFTQFAFA
SEPVLAWIGELRRLGIEVPIHIGIPGPASVRTLLKFAAVCGVSASTSVLKKYGLSITQLL
SSAGPDALVNEYATGLSNAEYGDVRLHFYPFGGLHKTVDWLQEYRTRPS
>A0A1J5KL59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. MedPE-SWcel|TrEMBL
MKVTEHIKEANGKTQFSFEILPPLKGQHIQSIFDNIDPLMEFKPPFIDVTYHREEYIYKD
LGNGLHKKKVVKKRPGTVGICAAIQNKYIVDAIPHLLCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKSETYFIPEKEGNAYASDLVTQVSQLNDGLYLDDELQNTSPTNFCIGVGAY
PEKHMEAPSLDSDIHFLKKKIKNGAGYIVTQMFFDNQKYFDFVKKCRKAGITVPIIPGLK
PIATKSQLNIIPHRFHVDLPEALIAEIVKCKDNKEVRKVGIAWCILQSKELQKAGIPILH
YYSMGKSDNIYDIAKAVF
>A0A378WF86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria zoodegmatis|TrEMBL
MTLHNQQRKKLSFEFFPTRTPEGRAKQVITRKQLSQFHPEFFSCTSGAGGSTRDGTMQAI
QDILSEGIAAAPHLPCVGMHAQEIIDLLNEYKALGVRHIVALRGDIPSGMGVGSDGLRYA
NELVSLIKTEFNNDFHIEVAAYPEYHPQSRSAEDDINNFVRKVKAGADSAITQYFYNADA
YFRFVDDVRGRGVDIPIIPGIMPIASFSKLSRFSDTCGAEIPRWLRLKLQSYADDTASIK
ALALDVVTEMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>A0A2K9ZG68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MAMSQAIHLRDQSGVLDDFSVEVTTKDTAQLAAMSGAIPKGTIISIPFLSTESDADRIRA
AKMVRQAGYVPLPHIAARRLGSESMLSAMLSALVNDAQVSRLLLVAGDADPPKGPFLDTA
TILRSGILEQHGISNVSIAGHPEGHPVQNAAMLTSALLEKRLIMEAANIEWSIFTQFAFA
SEPVLAWIGELRRLGIEVPIHIGIPGPASVRTLLKFAAVCGVSASTSVLKKYGLSITQLL
SSAGPDALVNEYATGLSNAEYGDVRLHFYPFGGLHKTVDWLQEYRTRPS
>A0A3G6R1S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium shandongense|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTAGGHASAMDLVHQINNLGRGKYLHNEDQECDEHNKFCVGVAG
YPEKHIEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVNKAREMGINVPIIPGI
KPIATKKHLKLLPQVFKIDLPEELISEVENAKNNDAVKQIGIEWAINQCRELLNFGVPVL
HFYSMGKSDNIKRVAGELF
>E3ZR79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria seeligeri FSL N1-067|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIIAIHKAYIGAGADIIQTN
TYGANYIKLSRYGLEDQVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDAKLPAAPL
EEIKRSFREQLYCFLLEGVDAILLETYYDLDELKTVLKIIRETTDLPVVANVSMHEPGLL
QNGQKLSDALEELIALGADVVGVNCRLGPYHMARALETVPLYDHAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQGGARIIGGCCGTTPDHIRALRKGLKSIKPVLAKEVRPIL
ELVPEEIVDEDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAKALNEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AIRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIKVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEQGRANEEGMQIARELIDSICTCFQGIYIITPFLRYDLSI
ELAKYVQSKQQVQIVSK
>A0A242W7X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar mexicanensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGVEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A519NLH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKIIDHIHNAKGKTLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDFIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKDETENALIDMQFLGIDN
VLVLRGDARKSDSSFIPTPNGHAFASDLLGQVADMNKGKYLHDDMANSERTDFCIGVAGY
P
>A0A1N7L2R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivivax lentus|TrEMBL
MTLRPDVSFEFFPPQSLEASFRLWDTVQTLAPLGPRFVSVTYGAGGTTRELTREAVGTIH
KHSGLRTAAHLTCVNATREETLGIARGFAEVGVTDIVALRGDPPKGQDRFVPTEGGFRDS
CELISALKETGDFTIRVGAYPDTHPEAPTETADVEYLKRKFDAGADEALTQFFFEAETFF
RFRDACEKAGIDKPIVPGIFPIENWKGARRFAEKCGTKIPQWVIDAFETATRDSREDLLA
TALCAELCSDLIDGGVDKLHFYTLNRPELTRDVCFALGVTPETRLENVA
>A0A519JTH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTEHIEKAQGKSLFSFEILPPLKGQNIQSIFDSCDPLMEFNPPFIDVTYHREEYEYKE
LPSGLLQKKIVKKRPGTVGICAAIQNKYDVDAIPHILCGGFSKEDTENFLIDMDFLGINN
VMALRGDAVKSETYFKPEKDGNEYASELVSQISNLNHGIYLDEDLQNSAKTNFCIGVAGY
PEKHMEAPSIDSDIYFLKQKIKNGADYVITQMFFDNKKFFDYVDKCRAAGITVPIIPGLK
PISTKKQLNQIPHRFSVDLPDDLIMSVVKAKDADAVKQIGIEWCIAQSKQLVKAGIPVLH
YYSMGKAENIRSIAKEVF
>M5URX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira sp. Fiocruz LV4135|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSRLDPDFVTVTYGAGGSTRSK
TAQILSEISKNYSFPTVSHFTCVGANQEQILKTLKEIRSSGIVNLMALRGDPPKGEGQFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPNAKNLEEDVENLKRKVDAGADFLVS
QLFFVNSIFENFLNLVRAAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIKDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A3C0E928|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
MKVIDLIKNSKEPVFSFEILPPLKGNSIQKVYHIIDKLREFDPKYINITSHHSEIVYLPQ
PDGNLKKTTVRKRPGTVAIAAAIQNKYGIQAVPHIICKGFTKEETEYALLDLNFLGINNL
LLLRGDSKPLDIAEKDLCLYHEHATDLQEQVNRFNQGIGLDGSKIEGIETPFSYGMACYP
EKHEEAPNMESDLFYLKEKVRNGADYVVTQMFFDNEKYYAFVERCRQEGIEVPIIPGIKP
VVFKNQLNVLPKVFRTDIPEAFASELRKCTTDEEVKAVGVEWCKAQCKDLLAHGVPGLHF
YTFMASDSVYKVAKEVY
>A7AGD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides merdae ATCC 43184|TrEMBL
MKVIDLINSSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQKTDIYHEHATDLQQQVNDFNKGIAIDGSVFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDDEAKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVYKVAKEVY
>A0A2K8ML16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Cra20|TrEMBL
MAAPLFADVAGDIEVSFEFFPPKTEKMEETLWESIQTLSPLGPRFVSVTYGAGGTTRERT
HNTVARIARETRIPAAAHLTCVEATREEIDQVAEEYWAAGVRHIVALRGDPPRAGEKFAS
HPGGYENAAALVAGLSKLHPFEISVAAYPECHPDSANATADLDNLKAKIDAGATRAITQF
FFEPETFFRFRDNAAKAGITAEIVPGIMPVMNFASVQRMSAMCGTAVPAWMGKLFEGLDE
HPAARQLVAATLTAELCRKLYAGDVRQFHFYTLNRAELSYAICHLLGLRPKVGAELVAA
>A0A0S3QVK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosulfidibacter takaii (strain DSM 17441 / JCM 13301 / NBRC 103674 / ABI70S6)|TrEMBL
MKVKDILRQYGLIISYEFFPPKRPEDERIFWETVERLSYWNPDFVSVTYGAGGSTHDKSL
EIAAKLRKIGYNVVAHLTCVSSTKEKIKETLNILKSKNIENILALRGDIPNDPSFKFPED
GFRYAYQLVEFIHKNNGFCVGVAGYPEGHPEAPSLEKDVEYLKLKVEKGADFVVTQLFFK
NEYYFNFLELAGSKGIHVPIIPGILPITSYNQIVRFTQLCGATIPKELMEIVERFKDSPE
DLRKAGIEYTVKQCAELLEKGVRFLHFYTLNRSPATETILRELNIAPQRH
>A0A315CBS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. Jir72|TrEMBL
MSGLKLPISLEFFPPKTPEGAEKLRGVREKLYALKPEFCSVTYGAGGSTQEGTFSTVSAI
LSEGVAAASHFSCIGATKASVREELATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLV
AFIRAETGDDFHIEVAAYPEIHPQAKSPESDLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGFGDDVESIKAFGV
DVVSDLCEQLINGGVPALHFYTMNQSAATLGVLSGLNGR
>F0ZME6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyostelium purpureum|TrEMBL
MTSMKIIDKINQKKESNVPFYSFEYFPPKTMEGVQNLYDRLGRMLLFEPLFIDITWGAGG
STSALTLEIAEKAQNVCGLETMMHLTCTNMPVNEIIYALDKAKATGIRNILALRGDPPRG
EEWKKIEGGFGYACDLVKFIRERYGDYFGICVAGYPEGHSDCTSFEDDITHLKAKVDAGA
DLIITQLFYDVDVFCDFVKKCREVGINCPIIPGIMPIQTYAGFVRMTTLSKTKVPQYIMD
NLEPIKDNDEEVKKYGVRLCVEMSKRLLEFGVEGLHFYTLNLERSVRKVLKGLELVTPDQ
LSPYLPWAQSAAGNRLKEEVRPIFWQNRPRSYIARTGSWDEFPNGRWGDYRSPAFGDLSD
YHLGGVAVSTSDVVSTATTNIYGDSHSTEQDIYNVFASYCEGKIKKLPWNDTPLSLESEN
IKDQLVFLNKNGFLTINSQPAINGVPSTDKQHGWGGKNGFIYKKAYIEFFTSPENAQKLI
EYIKKCPMITYHAVNRKGDQKTNTKGTNAVTWGIFPGKEIIQPTVVDHNSFMVWKDEAFA
LWETQWANNYEKDSKSREILDKMIDSYYLFNIVDNNFISGNIFSPFSDLVNNLSSPTLNG
LSLNNN
>A0A4S3MK72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmobacter aestuarii|TrEMBL
MSQTPRISFEFFPPQTLEASFRLWETVQMLAPLSPEFVSVTYGAGGTTRKLTHDAVTTIG
KSYGLNVAAHLTCVDASRAQTLEIANAYADAGVTQIVALRGDAPKGAARFNPHPEGFANS
IELIEALAATGRFTLRVGAYPEPHPDAADTLADVRWLKRKIDAGASAAITQFFFEAETFL
RFRDLCVKEGITAPIIPGILPIENFGGVKRFAQRCGAQVPAWLDEAYAAAARDGREDLLS
VALCTELCDTLISEGVEDLHFYTLNRPNLTRDVCHALGVTPEVALEKVA
>A0A349A033|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MESKQTPDSNRGTEEQKKDHGNRFKEALTQRRGFVYTLELVPGRGSRGETIEQVLDMAQR
AAAGGRVHAVSITDNPGGRPALAPEAIGLEVLHFGIDPIIHFTCRDKSRNQIESALYGLD
RVGLRNILAITGDYPEGESKPVFDLDSVQLLQFATQMNAGLENDVKVPGAGTRVPPTALF
KGCAVSPFKQLESETMAQYFKLLKKVRAGADFAITQVGYDVRKFDELLRVMRSYNIDVPV
IGNVFVLSLGTARVMNRKLIPGCVVTKALVEQLECESRQPDKGKAARFVRAAKLIAVLRG
LGYSGAHIGGPNLKYEDVERIIVTSEELTPSWREYVQEFSFPQENGYYLFQKDDETGLNS
DVPSVRTNHGGKIPGYALMRFFHRVVFDLEAPLYGAARAFYRALEGTRFEEHFGVLEHFI
KIITSRCRKCGDCALSDIAFLCPHSQCPKHLLNGPCGGSSEGWCEVYPGKRRCIYVKAYE
RLKIYGEEESLKETYVPPCNWQLNQSSSWANYFLGKDHSANNKCGKEPAKS
>A0A7Y9S5Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychromicrobium silvestre|TrEMBL
MSRSITPANRQATLELISDYSLEMTARDVPELIEAKDSIPAGTKINVTFLGTEDLEMRVD
AAKVVRALGFVPVPHISARRLASRAQLEEFLSRLQAVGATEHVFVVGGDPATPEGPYQDS
YGVIRTGLLRDYGVKEVSIAGYPEGHPDIPQDVLWQALDDKSLALSQQGLTATILTQFTF
DTSPVLAWINAVRERDIDSAIRVGTPGPAGIRRLLGFARRFGIGANAMIVKKYGFSLTNL
MGTAGPDTFVTDLSALLAAEPSSGPVGLHFYTFGGLKASSEWAGRFTALAEETAR
>A0A534S1P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
AVAAAREVCNLAVAVTITLTADDRTLLDDSPEQVAECLVKLGPDAIGVNCGHGPAQALRV
IRAMRPALGRVPLIARPNAGGPQQVGGRFLYPATPDYFAENARLLLAEGVSVIGGCCGTG
PAHVRAMAAALREPRAPVVQVGPSPTIEQAPDLASKGTELSAKLAEGRFVIAVELDPPRG
FSTAGMLAGAETLAETGADVIDVADSPMARMRMSPWAACRLIQEQVGIETVLHFPTRGRN
LLRLQGDLLAVHALGIRDLFVCLGDPMEVGDYPGGTDTVDVAPTGLISLITGSFNRGRDH
AGASIGEPTSFVVGCALNPAAPDLERECRVLRRKIDAGAAFALSQPVFSAEPLERVRAAY
EARHGALTLPILAGLLPLASGRHAEFLHNEVPGVSIPEEIRDRLRAAGASGKRIGLELAR
ELAHELRGAAAGVYLMPPFGRFDIAAELVETLRRA
>A0A8J7VS85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coralloluteibacterium stylophorae|TrEMBL
MLPISFEFYPPKTEDQRAQLDRTAKKLAVHAPEYVSCTFGAGGSTLSHTPETVRRLRQQH
GLDAAPHLSCVGGSRQEIRELLKLYRAIGCSRIVALRGDLPSGMGHPGDLRYASELVAFI
REEFGDRFRVEVGCYPEVHPQADDALADLRHFKAKVDAGADAAITQYFYNADAYFHFVDS
ARRSGVDVPIVPGVMPIANFSQLRRFSEACGAEIPRWMHKRMQALGDDADGVREFAADLV
ATLCRRLIDGGAPALHFYTLNLARPVSAVLARLS
>A0A7V2U100|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
FKKQEAEVLAQYFKLCKKVASGADFIITQVGYDARKFDEVLRFMRQQGIRVPIIGNVYIL
NRPVARVMNRGDVPGCVVTHDLYRAIDKESGAPDRGKAARLTRAAKLIAVLRGIGYQGVH
LGGPNLKYEDVEWVIEKGREFFARWQDWVREFSFPQEGGFYLFTEDSGSGLNSNVPNLRR
LHPRRKWGYRCMRLLHRFMFVPGAPFHKPASWFFGKLDGTRWEIPFTELEYWVKFASSRC
QRCGDCTLAEIAFLCPQSQCAKFLLNGQCGGSREGWCEVYPGKKRCIYVRAYERLRAYRE
EETLKDGYIPPRDWDLAGTSSWANYFLGRDHQRLRGPAGANSPPSVFGPQSGGWG
>A0A7V4GGP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTGGRAGFVERLRERPLVFDGAMGTMLYARGVFVNTCYEEVCLSQPALVSRIHREYVQAG
AEAIETNSFGANRLRLRPFGLGERVAEINRAAVRLAREAAGETVWVAGSVGPCTAPGAAP
AVSGAAIEEAFAEHIGALVEAGVDLILLETFTRLEELLLAVRVAARHDVPLVASFALDEG
GRTVGDGTDAEALATALEQEPAVAALGLNCGTGPSGAYENLRRVLAVARKPVVVMPNADV
PQVIQGRRVRVATPEYFAEYAKRYVKLGARGVGGCCGTTPEHVREAARALRGLAEVKRHA
VVAAAAVEPAAGAAAVVPRAEKSRLARRLAAGELVTTCELLPPKSVDLSGLLRKARQCRE
AGVDAINVPDGPRASARVSSMIAALAIEREVGIEAVLHYACRDRNLIGMQSDLLGGFAAG
LRNVLIVTGDPPKLGDYPDATGVFDIDAIGLTQLARNLNRGLDAAGHPIDPPTALHHGVG
ADPGAPDQARELDRLRRKLEAGAEFIVTQPVFRPEVLFRFLDAIEAFRGGVPLIAGVWPL
VSLRNAEFLQNEVPGVDIPPAILERMARAGSGEEAKREGVAIARETIAAIRGRVQGIQVS
APLGLVALALAALADVLPPRGDATAGPAGGGGR
>A0A7C4SMM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSKLSEALARGEFAVTSEVGPPKGTRVDELMAKAALLARWTHAVNVTEQQHSCMKLSSLA
ACALLAQRGVEPIVHAVCRDRNRVALQSDLLAAWTLGIRNVLVLTGDHPRMGDHPEALPV
FDLDSVQLLLAVQTLNRGQDLAGNALDGAPDFFAGAVVNPTSDALELQILKMKKKIAAGA
RFFQTQAVFAPERLEAFMERAASLRVPVLAGLVLPKSPTLARFMKEKVPGMYVPDELIAE
LAAVPKADRRKKAVEVAARIIRRIRPVCQGVHIMALGWEDLLPDILAEAGLREKPWEDPD
NPHIPE
>A0A7C5FG31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGLREAFESGKFVVTAEVGPLKGTDITEIKEVAHLLKGKVDGTNVTDQQSAVMRLGSMVT
CYLLKQEGLDPILQVTCRDRNRLAIQSDLLSAHVLGIRNVLAITGDYPTLGDHPDAKAVY
DVDSVQLVWMINRLNQGYDVAGNELQGKTDFFIGAVVTPITDTEAAFELQLIKMEKKIEA
GAKFFQTQAVYDIDAFAKFMKRAEKFGVPVLAGIIPLKSVGMARYMNKNVAGVFVPEHLI
EEMQKAEKPAQKGLEIAARLIREVKDLCQGVHIMAIGWEKKVPEILELAGLI
>A0A353SVP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKKAPLIFDGAMGTVIYDRGVFINTCYDELCLTNPKLILQIHRDYVEAGAEVIETNTFGA
NPIRLKPYGLAEKTEAINRAAVRLAREAAGEEVFVAGSVGPCTESRQRMPEEFAPEVEGA
FRTQMEALAAEGVDLFLLETFSHLNELQLAARVAKEFGRPVLASFVLNDRGETALGMRAE
TMASALSADDNVDIVGINCGTGPSGTFDALQAILPLTRKPVVAMPNAGMPREISGRVMYL
TSPEYFTEYAKKFIELGVRGVGGCCGTTPAHIRMAARAVKPLRVMKRRVEAKPLLRQETL
VYAVPTERKSRLAAKLCAGRKVTSVELVPPKSSDMTALLAKARQCAEAGVDAINIPDGPR
ASARVSPMISALTILQEVGIEPILHYCCRDRNLIGMQSDLLGGYAAKLANFLIITGDPPK
LGEYPDVTGVFDVDSIGLVQVAANLNRGLDIGGNPIEPPTGLFIGVGANPCAVDMEREID
RYFRKIDAGAEFAITQPVFDPEALLRFLDRVGTYRRKIPVLAGVWPLLSFKNAEFMNNEV
PGVVVPKPILDRMARCKTREDGRKAGIEIARGIVERISDRVDGFQVSAPLGHVETALAVL
AKSF
>A0A7C2NIF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIADLYARGGPVFSFEFFPPKSDEGYRALYETIGDLKRLEPGFVSVTCGASGSTRHKTA
DLVVRIQRDLGLTAMAHVVCTGTTVEELRDNLAWMRGEGIENVLALRGDAPKDQPEWRPV
PGGFRHASELARFVRANFDYCIGGACYPEKHPQAPSVEEDLAHLKEKVDAGAQFLITQLF
FDNEDYWRFVERARGLGIGVPIVPGIMPIVSAANLRHMLTLSPGSKRPVELERALDEAGA
NPDAALDVGVAWATRQCRELLARGAPGIHFYTLNRSPATRRVHAALAAR
>A0A8J6N9N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfatifera sulfidica|TrEMBL
MRQTPEATAIFKDSLFDKQDFTLTFELVPGRGSGGKRLERILDFAGAARTDGRIKALSIT
DNPGGHPALSPTPLGLEIHEIGIEPLIHFSLKDKNRNMAESQLFECHRHGLQSLLVLGGD
YPRYGFQGQAMPVFDLDSVQLLDLISHLRHSGSLEKEAPGGRMELQPMDFLAGCVVSPFK
TREDEQVFQYRKLLSKVQSGANFIISQLGFDMDKYRELIRFCQNSQLNQPLMANIFIPSL
PVAMIMNRGQVPGVLFPDRLLQIMEQEATTRDRGDEARLLRAAKMIAIIKGMGYDGVHVG
GNNLNFDKISFVLDQAESFGTNWRDLEQEVHFPAEKTWYFYGSQSPRGTTTRPSRYLLNK
LIHDSVFEQDGPLFSANERLARWSSKTPTRYRIYTLIEACIKKILFRCRMCGDCTLAESG
YLCPQSGCPKRMINGPCGGSLDGWCEVYPKERLCFWVRVYKQEARGRHTQKISPCPHLPP
KDWNLHTRSSWINYFTGRDHHKLNDKDNP
>A0A7X8CDP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKAGSNLEKVFRAGHFAVTCECGPPKGADVEHLKKKVNIIKGYVDAANVTDNQTAVVRMS
SIGASAILVQNGIEPIMQMVTRDRNRIAAQSDVFGAYALGIRNMLCLSGDHQKFGNHPFA
KNVFDIDSIQLLDMMRVLRDEGKMNCGEEVEGGIKMFFGAAANPFADPYEFRVIRMAKKI
MAGADFIQTQCIYDMKRFKEFMKMACDMGLDKKCFIMAGLTPLKSAGMANYMNKRVSGIT
IPDEIIQRIKGVPKDQQAEEGIKLLIEQIEEVKEIPGIAGVHVMAIEWEEKIPEIMERAK
LLPRPQV
>A0A0D6ZFZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus delbrueckii subsp. bulgaricus|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADYLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILNRYQNSKEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHRS
>A0A2N6BFA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTEFYSKFQESLLDKDTFSITWELVPGRGSFEVAQEVVFSSAEEAVKGGKVHALTITDNP
GGNPAISSEMLGAEIIKMGIEPLVHFTCKDKNRNQLESLLYGMERENVRNLLVMTGDYTY
SGFRGRSKPVFDLDPAQLLSLITEMNQGLVVPTFKGTATLKPTHFFAGAAVSPFKAVESE
QMGQYYKLKKKLDAGAQFIVTQLGYDFRKIQEAKMMMETLGYGNVPIVGNIYLLPLGAAR
LMNRNGLPGCVVTNELVDVIAKEAEAEDKGKGKRLERAAKMYAFMKTQGFAGVHIGGHGM
KYDDVEVIIQMGEELLPKVDEFVKEFDFSQPNGWYYFEKDEATGLNTTTPTDRSDKPSAG
LGYKTFKVLHHSMFEKKGFLFGPMRAISRAIDGSGMEHFFTRVEHFMKVMTNECMHCGDC
ALFDLAYLCPMSQCVKNQRNGPCGGSYNGWCEVYENKKKCIYVRAYDRLKSHGAEDVLGD
YQVPPIDFDLRWTASWLNFFMGRDHSAKRLGIMPPEKKD
>A0A7V4K168|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRWTERLRRGEFLVVVEVLPPKGADLQGFEKKLVPVKGLVDAVYLPSLQGAVMRASPWGV
AKPLRDRGYEVIFEVSCAHQNRLALQAELLGAALLGLENVVVVEGDDPKLGDHPEAKPVF
DVHVKELLGGLAAMKRGKDMAGGDLEAPVYFCVGAKVDASLDGPSLEGEWEAMAQMVELG
VEFFFTTSVYDLRKMERFMQGASKLGVPVLAGVMLLKSAGMARYLQKHVPGVYIPEEVVE
RLLYAADRAYASVKLASELIRGLKGICQGVEIVTLGWEDKVPMVLEEVSS
>A0A7C8A5N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSELKSGSNLEKVLKAGHFAFTGECGPPKGANVEHLKEKIEPLKGMVDAVNVTDNQTAVV
RMSSWAASTIMCQEGVEPNFQMVCRDRNRLAIQADILGVYAMGIRNMLCLSGDHQRFGNH
PESKNVYDIDSMQLIALVKKMRDEGKFLNGEEIDVPPRLFIGAAANPFADPFEFRVYRLA
KKIDAGADFIQTQCIYNMDRFKEFIKQAVHMGLHEKCYILAGVTPMKSVGMALYMAKQVP
GMDVPESLIKRLRGAGKGKAGEEGIRFALEQIEEFKEMEGVAGVHLMAIEWEHKVPEIAE
RAGVLPRPVV
>A0A7C4FPF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MREKLRGDGFLKLVEVLPPKGARGDVFEERLIPLKGLVDAIYIPQLPGAVMRAGSAFCAH
LLHVRGYEVIFEVNCAHSNRLAIQAELLGAGLLGLRNAVLSEGDEPKWGDHPEAKAVFDV
TLKELLQIVKAFREGKDLVGGDLEGALDLCVGVKVDASLQGEALKKEWDRMEEIAHLGVE
FFLSSSVYDLEQLERFMEGASKIGVPVIAGLIILKSAGMARYINKHVSGVMIPEGIIEKL
LRSPDKELASIEVAVEALKGIRKVCKGVNFITIGWEDKVPQILKEAEGL
>A0A523CIC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLAEKKSPFRQSLVTPAQFTITLELVPSRGGHSREHDRTLELAEKLARDPRIQAVSITEN
AGGQAALSPEVLGREIQQMGLDVIVHFSSKDKNRNQMESLLFAWDRLGIRDLLVITGDYP
QEGYQGCPKPVFDLGSVHVLDLISRMNKGNYGPDRGKGAIQPTSFLMGVALSPFKRLEAE
LLMQYAKLHRKAEQGADYIITQVGYDARKFHELLQYVQQSNLNLPVLGNVFIPNLTVAAL
MHTGKIPGCIITDRLYGEIRREATSPDKGKQARLLRGAKLLAILKGLGYAGAHLGGPGLT
YENIDYLLSTADSLAGNWQDLVPEMDYWHQDGFYLYTKDAATGLNTTEPAPRDERQAGLQ
VNYRMARLVHNLAFTKDAPLYPACKKICLALEGGGLDNGLTHLEHVTKFLLFGCQNCGDC
TLGDLAFVCPQAGCAKYLLNGPCGGSRDGWCEVYPGKKRCLYVRVYERLAAHGLPESMQR
GFVPPRNWALNNTSSWLNFFRGLDHAGESQK
>A0A7K2AFN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MGGSPRRRRLAGESPEHRAARAAVIEASSFEVIPLRSLDAAVEALPDGSRVSVTASPAKG
LAATQEITEQLNAAGHAAVPHLSARLVRDRTHTRALAAWLRSTQIEEIFLVGGDVAEPGR
YPDALSFLGDLLEADPGLRRVGVTAYPDGHPLIDPATLDSALTDKQLMLAEAGLAGYSST
QMCFDPERIAGWLRRQRRRGMDLPLHLGIAGVVDRAKLLSIGLRLGIGQSLRYLRKNRRA
VTRLLTAPHYDPNDLLVPLSPHLVELDIRALHIFTFNQVAATAAWREQNLR
>A0A509L646|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSNFEKVLKAGHFAFTGELGPPRGCNIEHIKEKASFLKDNVDMVNITDNQTAMVRMS
SWAAAIILMGEGLEPNYQMVCRDRNRLAMQADLLGAYAHGLRNILCLSGDHQQFGDHPFS
KGVFDIDSMQLVAMVKKMRDEGKFLGGADIDQPPKMFIGAAANPFAEPFEWRVHRLAKKV
EAGADFIQTQCVYNMPKIREWIKQANDMGLTEKTYILPGVTPMKSIGMARYMQSKVPGMD
VPDEIIKRLRGVHRKKVADEGIAIACEQIEEFKGMKGVAGVHLMAIEWEHKVPEIAERAK
VLPRPEV
>A0A3D0I0B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MVSREAPGRSQISIELVPRSKESLDADLRALREHFPHVSTVNIPDLLRFPVRSWDACQRA
RAYVERAIAHLRSMDFDLTGPFVLKDVLATRGLSEVLVVRGDTPQELGRRVYPTRPTELI
AAIKSQLPGIKVYASFDPYRSSLHAAGELVRAKLEAGADGFFTQPFFDLRQMDVCAELLA
GCEVYWGVSPVLGPQTRRYWEVKNRVVFPAAFEPTLAWNRRFAAACLAWVREHGAHIYFM
PIRTDLVTYLEDIL
>A0A2N2H7G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-21|TrEMBL
MKAGSNLEKVLRAGHFAFTGELGPPRGANVEHVKKKAAFLKGNVDSVNITDNQTAMVRMS
SWAASLLLIQEGLEPNFQMVCRDRNRLAMQSDVLGAYALGIRNMLCLSGDHPKFGDHPTS
KGVFDIDSIQLIDMVKRMRDDGKFLSGGDLDIPPKMFIGAAANPFAEPHEWRVFRLAKKI
KAGADFIQTQCIYNMDRFREFMKKAVDMGLHEQCYILAGVTPMKSVGMAQYMAKSVPGMD
VPEALIKRLRDAGKGKAAEEGIKIAVEQIQEFKQMKGVAGVHLMAIEWEHMVPEIAQKAG
VLPRPKV
>A0A496YX40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSFQKQLSSGEFVVLAEMNTPKGVDISEMVTNARKIKERVDGAIIPDMDNGVMRMSALAG
GVLMRQQGIEPIIHVYGRDRNRMAIQGDLLAAHVLGIQNLLVVHGEEMSYGDHVDAKPVD
DLDELGIIRAIQSLQEGVDMAGFDLKGSPNFTVGCMIKPFADDTALDQELEKAQGKISAG
AQFVIFPPVFDLERLSAFVQKAKSLGVPIISTVFLLKTVGIARYMATYEPGVFISEDLIK
RLRRAPDREMEGVILAGETIKALRELCQGVRIVTLGWEHRLPAILDYAGL
>A0A661ICG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEFRERLNTGGFLKLVEVLPPKGVGAEQFEKRLVPVKGKVDAVYIPSLQGGIMRVESWAA
AKYLQDRGYETIFEVCCAHKNRVALQAEVLGGAFLGLRNVMVVAGDDPKLGDHPEAKAVF
DVDVMGLLEGIKGLKKGYDMAGSDLEGAPDLCVGAKVDASAQGPLLELELRDMERKIRLG
VEFFITTTVYDLEQLQRFMERAKEFKVPVIAGLMILKSAGMARYINKHVEGVLIPEGVIE
RLLKAPDKVEESARIAAEMIQGMREICQGVNLIPIGWEEKVPLVLEEAGL
>A0A559KAX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. JC52|TrEMBL
MLKDKIKTKQAGIITYGMTPPKQTHPPEKMAEISQKQIERLTGLDIDALILYDVQDEADR
IDVERPFPYLQTMDPAIYSKEYLHQLAVPKIIYRCVGKYSEAELADWIKADAEQDRFSVF
VGASSSQQQVSLRLPDAYQLSKGLNPQLSFGGVVIPERHMTKVDEHLRVVSKMQQGCDFF
VSQATYNVEASKNFLSDYYYYCQENGLDMVPILFNLAPCGSLKTLEFMKWLGISIPRWLE
NDLKYSSDVLDRSISVSQNIFEELFEFGMEKGIPVGCSVESVSTRKVEIEASIQLVKNIN
AYLKRS
>A0A534U531|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIRDLFTGDGPVFSFEFFPPKTDEGERKLLETVRRLKELRPGFVSVTKTGAKPAEKTIE
ITARIKHELGIEAMAHMTCATAGRAEMRRLFELIRDAGIENVLALRGDPPRDQPTFVRPP
DGFDYACELVRFIREHGYGFCLGGAGYPETHPECPTAELDLANLKCKVDAGAEFVITQLF
YENARFFAFVDRARAAGITVPIVPGIMPITNVAQIERIAALSGARIPPALQRDLDAARGD
DAAALQVGVAYATTQCRELLAAGVPGVHFYTLNQSPATSAILRALRAEQAAS
>A0A5J5KXH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria coralli|TrEMBL
MPSSRSAVEAVARSLTSPRFEVLPTAGAAELVAQHLPPGRIVTVTASPSRGLEATLALAE
GLSALGYRAVPHLAARMVTDAEELAEIVTRLRAAGIDEVFIPSGDAAEAGAYPDAFSLLH
ALDELGRPFASTGITAYPESHPTIPDDMTIQAMWDKRELATTMVSNMTFDPQVVQTWLTR
VRRRGVTLPLWLGIPGPVSTAQLLRVASRIGVGDSTRFLTKHPRAVMRLLRPDGFSSESF
LRHLGPALAREESRIAGLHVFTFNHVAEAETWRTDLLSRLGKEHHLPA
>A0A534SFJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTLSVEFFPPKTEKGEENLFSEIETIKRLNPGFCSVTYGAGGSTREKTIDLVETIHDGCG
LEVMCHLTVVGQSKAEARAILHRLKGKGIENLLALGGDPPQGMADWQPHEDGFQHAIELV
REAVAVGGFSVGVAGFPEVHPRAESRPSDMKFLKEKVEAGAAVVITQLFFDNDDYYRFVE
DLRKLGVRAPIVPGVLPILSAPQVRRFTALCGAKIPARLERELAKVEHDDEAAIEMGIEY
ATRQCAELIKFGISGLHFYSLNKSYSVKAICKNLGL
>A0A2U3DVT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Purpureocillium lilacinum|TrEMBL
MDKITDKIAALPPDAEYFSLEFFPPKTAMGFSNLRHRLQRMEQALRPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRRLIDKALEDAKVLGIRNILALRGDPPRNEE
YRDADDTDDGAAEDFTWAIDLVRYIRSKHGDYFCIGVAAYPEGHADESHPLGQSLEHDLP
YLVDKVQAGADFIMTQLFFDIDAYDKFEKTLREHPSGAFKDIIIMPGLMPIQSYQMIKRT
TKLSHAKMPEAIMSRLNAVKGDDEKVKLVGVDIVSELIEQIRTIKSRSTGRKGFHFYTLN
LEKAVAFIVERTGLIPDTSDNEEAVVEDTSAVPTLQVNGNVRLRTRSHSRTSRRQSSVGS
DPHNRVIVGSQRPSHPEWEASGQEAGVPAEAINSRANTLAISEGEGVLGREATWDDFPNG
RFGDSRSPAYGEIDGYGVSLHMSVASAVRLWGHPKTRQDISDIFVRHMKGQLEAIPWSEE
ELMPESSAIQPRLVELNSKGWWTVASQPAVNGLPSNDSTFGWGPPNGFVFQKAFVELFIP
SSDWKVLAERLRAPEVRDVVCFYSANAKGEFESSDVSGAANTSTGEASTNAVTWGVFPGK
EIVTPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLNGIKEDYWLVNIIHHDFVD
KEALWKLLMA
>A0A661R725|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEFVSAGRLERVMKAGHLGVTSECGPPRGSDPEEVRKKGMLIKDYVDAINVTDNQTAMT
RMSSLAACVHLKLLGIEPVLQMVTRDRNRVALQSDILGAASFDIPNMLCLSGDHQSFGDC
AQGQNVHDLDSMQLVQTVRHMRDEGKFLGGDDIKRPPKIFVGAAANPFADPFEIRVPRLA
KKIACGAEFIQTQCIYNIDKFKEWIRRAVDRGLHEKAFIMAGMTPMKSVGMAKYMKKKVP
GMDVPDEVIARLAGVEKGKQAQEGIDICVEHIQQLKEVTGVAGFHIMAIEWEEKVPEIVE
RSGLYPRPEI
>A0A534R074|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
PVELVTRIRALGIEAAAHVTCIEAGREELAAHYELIAARGIENVVAIRGDRPGEGSFHPP
LNGFRYAVDMIRFVRARGHKLCLVGGGHPEGHPECRDLELNIQHLKMKVDAGLDAVITQL
FYDNADYFAFVERARRAGIGVPLVPGIMPITNVPQIERITALSGNQIPAALRAALERARD
DEQAALAVGVEWATRQCAELLRSGAPGIHFYTLNKSPATRAIFENLCSEGLVGAPLPRLA
TPSPIR
>A0A350RNR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp|TrEMBL
MKIIDLLKSDKVTVSFEVFPPKSEANYESIYNAAMNVAALKPAYMSVTYGAGGSTSKSTL
DIAGDIQKRYDVCTIAHLTCAGADKDDIHKSLDGMKTKGIENILALRGDRPKDYDGDPFA
HYRYASELISEIKEYAGDSFCIGGACYPEGHVDAANKKEDIGNLKKKIEAGCEFLTTQMF
FDNNIYYNFLYRIREQGIVVPVVPGIMPITRATQVANALKLSGSNMPERFRNLVDHFGTN
PAAMQQAGIAYATDQIIDLIANGINHIHVYSMNKPEVAAGIQKNLSEIIK
>A0A2M8AN88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium CG_4_9_14_3_um_filter_33_16|TrEMBL
MKVTDHIKKANGKTLFSFEIIPPQKGRNIQELYNNIDPLMEFNPPFIDVTTSREEYVYID
KGEGLLDRKITRMRPGTVGICAAIKHKYNVDTIPHVLCGGFTKEETEYVLVDCHYLGIDN
VMALRGDAMKHQQYFEPAEGGHAYASGLVKQMSDLNKGKYLHDVVESDYKTNFCIGVAGY
PEKHLEAPSLNTDLKRLKEKVDAGADYVVTQMF
>A0A661TDA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSNLEKVLEAGHFAFTGELGPPRGANADEVREKAAYLKGNVDAVNITDNQTAVVRMS
SWAASLILIQEGLEPNFQMVCRDRNRLAMQSDILGASAHGIRNMLCLSGDHQSFGDHPLA
LGVFDVDSTQLISMVRKMRDEGTFMSGAELDGSPKIFIGAASNPFAVPYEWRPYRLAKKI
NAGADF
>A0A660N8X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoanaerobaculum sp|TrEMBL
MHNQGKVSIREFLQNNVLIFDGAMGTYYSSIVNEPAINCEMANIQHPEVIESIHKEYIAA
GAHAIKTNTFGVNRKNFGENSKLLEQLVDAAVEIARRSANDTTYIFADIGPIDGEEEEKV
VEQYKEVVDLFLKQGINDFLFETNSSITGLFETARYIKEKSPEAFIINSFAVLPDGYSSE
GRYYRKLLSRNEENASVDILGLNCVCGPAHMLTLLENVHTTDISIMPNAGYPVVRGRRTF
YSNGPTYYAEQLENIVKKGVQIVGGCCGTTPAHIKAFVERLGSTSFVRQKIQPKSVVVTE
EKDESKNHLWRKLEEGKKVIAVELDSPKNADLSGFMESARRLQTAGVDTLTIADCPIAVA
RMDSALLACKVKRELGLDVIPHMTCRDRNINAIKALLLGMHAEEIYNILAITGDPIPNAQ
RNEVSSVYQFNSRKLAAYIDSLNAEVFDEGYKIYGALNVNARNFEVELRRAEQKIEHGMV
GFLTQPVLTQEAVENLAKARERLSAKILGGVIPVVSEKNARFMDSEVNGIRVSEEIISQY
VGKNREEGEQLAVEISLDMAKKIKPYIDGYYLITPFNRVALMEKIIEGLRE
>A0A1H9C371|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus equinus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPEKVLAIHKAYIEAGADVIQT
NTYAAKRHRLDGYGYGDKIKEINQAGVKIARQAAGEDTFVLGTVGALRGLKQCELTLDEI
IKETLEQVGYLLETEEIDGLLFETYYDEEEIIEVLKAVRPLTDLPIITNISIHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVSRKFVTP
MVEEAELIKAVKQSETIVDKVKRKVTIIAELDPPKTLDIRKFTKGVKALDEAGVAAITLA
DNSLAKTRICNVSIASLLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIKQLNKGIGYSGASIKKETTFTAAAAFNPNVKNLS
RCGRLIDRKIAAGADCFITQPIFNSEIIENLAELTRDYETPFFVGIMPITSYNNAIFLHN
EVPGIQLSDDFLAKLEVVKDDKEKCQQLALEESKQLIDHALKFFNGIYLITPFMRYDLTV
DLVEYIHQKVEQSHQIIP
>A0A6P7GGW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diabrotica virgifera virgifera|TrEMBL
MDCICYKGSRFISVNSYLHTMRETLINSLTKIPISIKPAFKKVSSDNFIKNVLTSDLRVS
IEICPNRALNEDLLSSIPFSFCSVTWRTPSNEQLEHVDQIPALILAKQLNSNGYNVLLHL
AGRYLKREQVVRILEEVKSAGIRNLFALQGDPSEIKEKDDKKCDFPYASDLVTFIRERHG
NYFCVGVAGYPEKHPQCENIEKDLQYLKFKVTRGADFIITQASYDYQRFLTFSQQCHLMG
INVPIIPGVFIISSHRTLTAMSKFCGVTIPRNIIDVVEAVKGNDDDVAKFGVQHATELIG
KIFENQHLFAGVHMFSLNNLELVKSVLQKTNINSECLVPLNA
>A0A2D0KY68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus sp. KJ12.1|TrEMBL
MSFFHANHQEALNQNLAELEGQIRVSFEFFPPQTAEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDANREELCNIAHDYWSSGIRHIVALRGD
LPNGSSKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRIPSWMTRMFE
GLDDDPESRSLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A645CG60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MREEKKVNAGAQFIQTQCIFDLEGFEHYLEALDRRDVLQRVKLMAGITPVRSLNAAIAMS
TVPGIKIPPAVFKRLENSADPKEESIQMTLELIQKIRVLPGISGIHFMAVGWESIVPRLI
QESGLSKN
>A0A8E3U9L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAARLKDYSPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIEFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLVEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A6N9T1W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiella pacifica|TrEMBL
MSQVNALSNSGIRVSFEFFPPKSDKMEENLWRSIERLAPMQPTFVSVTYGAGGSTRERTH
HTISRILNETNLTPAAHLTCVDASREDVSEVVRQYRDTGVKHFVALRGDSQAGVGGKYVA
REDGYRNAVELVAGLKSIDDFEISVAAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNDIFERYVERVRKAGIYIPIVPGIAPIHDFTKIARFAGATGASIPDWLARRFDGLEE
DEQTRSHVAAAFCAEQVLDLTRRGISDFHFYTMNRADLVYSICHILGLRAAQPENEEKAE
AAAAA
>A0A6P0JTV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kamptonema sp. SIO4C4|TrEMBL
MTRFRQAVQNKEFLITAEVMPPKGGSPKRMLEHARSLKGRVHAVNVTDGSRAVLRMSSLA
ASTILLQEGIEPVCQVACRDRNLIGLQGDLMGANALGIHNILALTGDPVKAGDHPKAKSV
FDLESVRLLKVIDKLNNGFDYNDKKLPNQKLDLFPGAAVDPQLKSFSGMQRRFERKLEAG
AQFFQSQLITDFERLDKFMTQVASIADKPVLAGIFLLKSAKNANFINKYVPGVNISDETI
NRLANAEDQLLEGMKIAAEQVRIAKDLCDGVHMMAVRREDLIPQILDLADIPPIK
>A0A6N9F6D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MSGRLRDWIAGDGVHLIDGAMGTVLYESGVFVNQCYDELNLSEPDLVLGVHADYVRAGAE
LIETNTFGANPVKLEPFGLEPSVYEINVTAARLARQAAGGRAEVLGAIGPLGIRIEPWGP
TSVDEATDLFGRQVAGLAEGGVDGFMLETFSDLDELLQAVRAVRRVAGDAPVFAQMTFGD
AGHTEYGATIEAAAAALDGAGADVIGLNCSVGPSSMLLGVERMVAATSRPVSASPNAGLP
RDIGDRKIYLASPEYMARYARRMVETGARFVGGCCGTSPEHTRLTATLLGTDGPGPARVS
VSSPSDAGGREAAEPPPLADRSALGRRLARGEFVGAAELTPPHGWDPGELVAGAARLRDA
GVHTVHIVDGPAHRSRIASLPAAIVVERELGMETVPHYSCRDRNMLGMLSDLLGAAAAGL
RNVFLITGDPPRGGPYDTGGVYDIDSIGLTNIVQQLNLGLDPGGSSIGVPTSFVKGVAVN
PGAVDPEEEIRRFAWKAEAGADFAVTQPIFDPENFLAFVREIEGFGVPLLVGLWPPLSLE
NAEFLAHEVPGVDVPSKVLERMARAQEGGAEAAAQEGVDVAREVLDAIRPHVAGALVSTP
GNEVD
>A0A0N1GNF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium OV320|TrEMBL
MQPASTVRTAVGTSLLDDFSLEMTGKDVPKLEEARHTIPPGTRINVTFLGNEDLRLRLDA
ARAVKRLGFVPVPHISARRLGSRDDFERFLAGLRADGTSDNVFLVGGDPAHPEGPYADAL
SLIGTGLLREYGVRHVGIAGYPEGHPSIDGAALWSALRDKHEALAAQPLEAGVITQFGFD
VDPVLAWVEEVRSRGVGLPIRIGVPGPAGVRRLMAYAARFGVGTSASVVKKYGFSLTNLM
GTAGPDRFLRALAAAHAPARHGELKIHFYTFGGLGATSDWAARFRKDSPA
>A0A0D0ISP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTSLSFEFYPPKTDEQRSQLDRTAAKLRSFRPEYVSCTFGAGGSTLSYTSETVRHLKQHH
RFEAAPHLSCVGGSRQEIRELLKLYRAIGCSRIVALRGDLPSGMGHPGDLRYAAELIDFI
RAEQGNAFRIEVGAYPETHPQASDALADLKHFKAKVDAGADAAITQYFYNADAYFHFVDA
VRALGVSVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGRKMQAYGDDSESIRAFGAEVV
AQLCQRLLEGGAPGLHFYTLNLAKPTTSVLKLLRS
>B1VHD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109)|TrEMBL
MSTMISFMSASNPHDHHEKASPLPGIPPQPTLQVPVSQAIRGYSPGKIPFSVEFMPPRDD
AAQTRLWNAAEAFHDLGVSFASITYGAGGSTRERTMEVAQQLAAKPLTTLMHLTLVDHSA
EELRAMLQDYARRGMTNVLALRGDPPGDPLGTWQPTPGGLNYASDLIELIRNTPECENFD
IGIASFPEGHYRAEDLEQDTQVTLHKLRLGADYSITQMFFDVENYLRLRDRLAAADPVHG
AKPVIPGLMPITSIRSVRRQMELAGGEVPVKILERLEKAAAGDEVANRDAVREVGIDITT
EMSERLIAEGAPNLHFMTMNNVRATQDVLHNLGMAPAWGPGYGQDMVR
>A0A2N5ZLA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinilabiliales bacterium|TrEMBL
MKVIDKIKQSKKALFTFELLPPLKGHTIQEIYDTIDPLMQFDPSYINITYHQQEVQYKTR
PDGLMEKRVIRKRPGTVAIAAAIQNKYKITVVPHMICGGFTKEETEDALIDLHFLGIDNL
LVLRGDPEKGKRKFIPVKGGHTYSSELIEQIIKLNKGKYLHADMEDAMPTDFSIGVAGYP
EKHVEAPNMETDLENLKLKVDKGADYIVTQLFFDNQKYFDFVEKCKERGINVPIIQGIKP
VSTLNDSSLLPQTFNIDLPNELIKEIKKCTSQEQVRQVGVEWAIMQSKELIKQGVPGIHY
YTLDQSDNIEKIARVIF
>D3GRZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O44:H18 (strain 042 / EAEC)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A427CN68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RTEHGDAFHIEVGAYPETHPQATDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWIGRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQG
>Q5WGV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus clausii (strain KSM-K16)|TrEMBL
MELRDKLKTSLIVGDGAMGTLLYEQGFDLCYEELNLSQPDAVYHVHRSYIEAGAKLLQTN
TYAANAVKLKKYGLNESVADINSAAVGIAKKAIGNNEQLALVGTIGGIRGFLHEDTENKV
ITAALLEQITALLEAGVDGLLFETFYDFEEAKEAVALARRLTDKAIIMNVSMGDIGVLNG
GIPLGEALEQLHELGADVLGINCRMGPYHMLRSLEQLELSSAFPLACYPNASLPGYRDGR
FVYASNTDYFYEMTGAFIEQGVHLIGGCCGTTPAHIAAIAKAVETNTPKTRSLIVRRPSQ
LQEEGPGRGERLNEPLDQLARRKQTIIVELDPPKKLMIAKFMEGAKALKEAGVDALTLAD
NSLANPRVDNQTLAMLVREQLGLRSLVHLTCRDRNLIGMQSHLMGLHLAELHDLLVITGD
PSKIGDFPGATSVYDVSSLKLLPLIKQMNEGISFSGNSLGSKATFSTAAAFNPHVKHLDK
AVRRLEKKIEAGADYFLTQPIFDEQQFEQLYDATKHLPVPIFVGIMPLTSSRNAEFLHNE
VPGMTLSDETRARMAACGNDKEKAEQEGLQIAMELADAASAYFNGLYLVTPFLRYELTAA
LATHCRAIANPINHTMEGERI
>A0A847QSI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MKICELFQMKKVFSFEVFPPRRIDSVSIIYDTIEKLKGLNPDFISVTYSAGGSESNTDTF
KIASAIKNNYGIESVAHLPSINHTKGEVLKMLEDLRTAGIENILALRGDVNPSFSPKNDF
KFASDLISFIKEHGDFNII
>A0A542SAE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. SLBN-35|TrEMBL
MRTHDRATVRRLLASARYEILPTATIEAKVLEAVPTEVPLTVTASPSMGLERTVGTAERL
AAAGYTVVPHLAARMVSGRAELVELAARLAEAGITNVFVPGGDADPVGDYHDAVSLLEDL
TAIGSPFAQIGVTGYPESHPKIHDDLTVQSMWDKRKHATYIVSNLTFDPAVIKDWLQRVR
RRGIDLPLLLGVPGPVERTKLLGMATKIGVGDSTRFLAKQKGLMTRLVAPGGFTGESFVE
RCAPTLGDPLMRVAGLHVYTFNQVAETEAWRRDWLARLDG
>A0A3S2EK64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.08.2.1|TrEMBL
VLGGAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTT
PPQLFLGAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTE
KCFILVGVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKE
ISGVSGVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITET
QVDMVKTAH
>A0A3D8PE24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus thiocyanatus|TrEMBL
MPTPSISFEFFPPRNLDQSFRLWDTARALAPLEPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDASREETLQIVQDYAAAGVHEIVALRGDAPQGQARFTPHPDGFADSV
ELIRAIAARGDMTIRCGAYPEPHPESPDTAADVAWLKRKVDAGASSAITQFFFDADTFFR
FRDACRAAGIAAPIIPGILPIQSWGGARRFAERCGTAVPQWAEDAFAAAGKQGEAQLALD
VCVTLCERLVEGGVDKLHFYTLNKPELVLKVCAALGIKPKDAVPRVA
>A0A165ITK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylona heveae (strain CBS 132557 / TC161)|TrEMBL
MTGCAKSLRSYVPSLRLQHRFDDWSTFKADHGRLTLCALGMDRMHDLGPSFIDVTWGAGG
RLSHLTCEMVNVAQSVYGLETCMHLTCTDMPRSKVDEALKEAYKAGCTNILALRGDPPRE
KEKWEATAGGFRYAKDLVKYIKEQYGDHFDIGVAGYPEGCEDQDDLELLMDHLKEKVDAG
GTFIVTQMFYDVDIFLDWVSKCRARGIDIPIIPGIMPIHTHAAFLRRANWTKCHVPESWT
AALEPVKNDDAAVREVGKGLIAEMCRRLLEAGILHLHFYTMNLAQATRMVLEELDLIPQS
TKALPWRPSLGLKRREENVRPIFWRNRNASYVVRTQDWDEFPNGRWGDSRSPAFGELDAY
DIGLKGTNEQNIKLWGQPKTLRDISEVFVSYLEKRLNALPWSETPITGEADILRDDLVDL
NRRGLLTVNSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELFISPELISEVITRIERNPD
LTYYAVNKDGELKTNAPSDGPNAVTWGVFPGQEIIQPTIVETISFLAWKDEAFRLGYDWA
RCHSASSPSRHLIGSMMDTWYLVNIVHNDFHEPRGIHPLFDGLEVPDFDVPFSAPEIVAD
DKSLKDVLVNGSEPAPAVNGVHVNGTTNGHAQAPN
>A0A315BLL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. MMS-10A-192|TrEMBL
MSALKLPISLEFFPPKTPEGAEKLRVVRQTLYGLKPEFCSVTYGAGGSTQEGTFATVGAI
LSEGVAAASHFSCIGATKASVRAELATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLV
AFIRAETGDDFHIEVAAYPEIHPQAKSPEADLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGVDVPIVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGYGDDIESIKAFGL
EVVSDLCEQLINGGVPAIHFYTMNQSAATLSVLSALKSR
>A0A2N3EC14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HGW-Alphaproteobacteria-11|TrEMBL
MSGDATREKRERTRVSFEFFPPKTPEMEQTLWRSIRRLEPLQPEFVSVTYGAGGSTRERT
HATVKRILDETTLEPVAHLTCVGATRTEVNDVIRAYWDAGIRHIVALRGDMPELGAPYRP
HPEGYQSTPELIAAIRTIGDFDVIVSAYPEKHPESVSLDADIELLKKKVDAGATRAITQF
VFDTEKHVRFLEKTQKAGISVPIVPGIMPTTNFKGTKRMAERCGASIPQWLEDYYIGLDD
ELETRKLIAAYVAAEQVNRLRAYGFDRFHFYTLNQADLTFAICHVLGLRPQAALTPAEPA
>A0A3M0C454|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eilatimonas milleporae|TrEMBL
MTAEPPQSLARSPGGPHEARAFGRGGNASLFAEDVRDVKISFEFFPPKTPKMEENLWSAV
QALAPLEPDFVSVTYGAGGSTRERTHRTVRRILDETALKPAAHLTCVGAPCGAVDDVIRE
YWSAGVRHLVALRGDAPDGADGYAPHPQGYENAAALVSGIRDIGDFEISVAAYPEKHPDS
ADWDADLDNLKRKIDAGATRAITQFFFETESYFRFLDRVEKGGIDVPIVPGILPVTNFRT
LTGFAARCGASVPDWLARLFDGLDERPATRNLVAATVAGEMCRRLHAGGVRAFHFYTLNR
AELAFAICHMLGHRAVPTGAGDHAKGESAA
>A0A7V1H721|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MSFSKALADGKFLVTTDVIPPKGVDLSSSLERLRSASGKVDAVNAVDLPSSAMRAGALPL
AAVLKKQGFEPILQMTCRDRNRLALQAELLGAYMLGITNILALTGDDMELGDDPDAKPVF
DLDSTGLLKAAWALEQGRDLAGNALKGAPAFCMGAAFDPGKNPAEHEIERIGQKIEAGAK
FFQTQPVFDAESFIKFMAKVPKIKTPVLGGILLLKSARMARFMNENVPGVDVPEHLALKM
EKTEHPAETSIEIAARLINEIKDFCGGIHIMNIHWEDRVPMVLEAAGLI
>A0A653Q6H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMGGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEQLVKYVR
EKQELKEGIN
>A0A3D3XSV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
VGICAALMHRYQTEAVPHVLCGGFTKEDTENVLIDLNFLGIENIVALRGDQAKGESYFTP
KPDGNNFAIDLVKQINDLNQGRYLDEDLQNTMPTSFCIGVAGYPEKHFEAPSLNIDIDHL
KAKVEAGADYIVTQLFFDNSKFFTFVDKCREAGITVPIVPGLKPLVTKRQLSILPQVFHV
DIPDTLAIEALKCKHNAEVCQLGIEWCIQQSKDLRQAGVPVLHYYSMGKSKIIYEIAKAI
F
>A0A0Q5HAL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas sp. Leaf324|TrEMBL
MIQRRDTRPPIRVSFEFFPPKTPAMEESLWSAIQRLAPLQPDFVSVTYGAGGSTRERTHH
TVERILKETDLAPAAHLTCVDASRAEVDDVVRQYRTTGVKHFVALRGDGQGGAGSAYVPH
PEGYRNGAELAAGIKAIDPEIEVSVSAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNDLYERYVERARRAGIYVPIVPGIVPIHDFGKVARFSAATGTSIPLWLAERFEGLEN
DPQTRSHVAAAVCAEQVLDLVDRGISDFHFYTMNRADLVYSICHILGLRETAPVREAAAA
>A0A1H7QPG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. DSM 46786|TrEMBL
MTPTVRELLATGHPTWSFEFFPPKTPAGEEQLWTALRQLERLHPSFVSVTYGAGGSTREG
TVAMTERIAADTTMTPLAHLTAVDHSVAELRHVISRLAAAGVRNIMALRGDPPGADPQAD
WVAHPEGLDYAAELVALIRSIGDFSVGVAAFPERHPRSPDFDTDVEMFVAKCRAGADFAI
TQMFFRAEDYLRMRDRVVERGCEVPVIAGVMPVTNVRQITRIVQLSGQAFPAELAERFEA
LDGDRPEEKAAVRALGVEVATDLCRRLLDEGVPGIHFITMNRSTATREVFANLAGRAPAV
R
>A0A1G2Z5L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RBG_13_63_9|TrEMBL
MVAALEQAFSQSDFVVTGEVGPPKGTDVGELIEHIDLLKDKVDGLNVTDNQSSVMRISSL
AVCRLIKDRGGEPILQLTCRDRNRMALQSELLAAAIQGIHNVLCLTGDYTSVGDHPQCKP
VFDLDSVQLLQTVGLMNQGKDLAGNEMQGATDLFPGAVVTPEADPIEPQMLKFEKKVAAG
ARFFQTQAVYDLDNFKRFMEQARKHDVKIMAGLVLLVSAGMARYMNKNVPGIFVPDALIK
EMAAAEKGKAVSVGIQVMGRMIRQLRDEKVCDGVHIMAIGKEDRVPDILKAAE
>Q84CU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
DPEFFSVTFGAGGSTTDRTKETVFEIQAEGYHAAPHISCISSSKEEIRELLAAYQAKGIK
RLVTLRGDVPSGEVSAGDFKYANELVSFIRQETGDWFHLEVAAYPEFHPEALSAAKDMAN
FKRKVEAGANSAITQYFYNSDAYFRFVDSCVADGISVPIVPGIMPIYNYTQLARFSGVCG
AEIPRWLRLRLEAYADDMPSLRALGIDVVSELCEVLLAGGVPSLHFYTLNQAGIISTIIN
NVGLEDATTQKRN
>A0A4Z1G7C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrytis hyacinthi|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHHIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAAL
EEVKNDDAAVRNIGKDLVAEMCRRILEAGVHHLHFYTMNLAQATRMVLDELRLTPSNQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLENSIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVSPDMMPELVRRIQQEP
DLTYYAVKKTGDVQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLNESFETSENGD
VDGVRFIEPQTIPLTNGEANGH
>A0A2D4QXY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
MKVTDYIKNATQTLFSFEILPPLKGKSIQSIYDGIDPLMEFNPKFVNVTYHREEYVYKEK
DNGLLEKVSIRKRPGTVGICAAIMNKYKVDAVPHLICGGFSKEETENALIDLQFLGIDNV
XALRGXPIKTEXTFKAHPKGHHYASDLIHQVNDMNHGKYCIDDIKMAPTDFCIGAAGYPE
XHFEAMNLKTDLIHLKEKVDAGATYIVTQMFFXNKKYFDFVKACXDFGINVPIIPGMKPI
KTLNHITFLPKFFHIDYPEALSNELLKCKTNADVEKVGIEWGIEQSKELMKEGVPCIHYY
TMSNSDAVKAIANQIF
>A0A7X2X226|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQPNFEGN
>A0A7X3CLR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus woosongensis|TrEMBL
MRPDLREKMKHEVLIGDGALGTYLYQLGFPVGISYEEFNLLRPEVIGDVHRRYIEAGAQL
LETNTFSANYYKLAKFGLESKVEEINKAAVRIARNVAGTDAYVAGAVGSIRGGKRVNVSV
PELNKYYEQQIAALLTEDVDALLFETFYDLEEMRIALGKARQHTSIPVICQFAVDQLGRT
LDGYSIKEAFGVLRQEGADVLGFNCHSGPKGIMSVMERLGGPLDIPLSVFPNAGLADYID
GEYVYGATPEYFGECALSFADLGARLVGGCCGTTPEHISAIAGALADYTAQPLQEGAALP
EVRPSIVAAERENQAGESFGGQAAEPSIVDLVKERHTVIVELDPPRDLDIRRFMDGAAAL
KEAGVDALTLADNSLAVTRMSNMALGHLVQSETGLRPLIHIACRDRNLIGTQSHMMGFDA
LGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKAKFVVG
AAFNPNVKHLHKAVERLEKKIASGADYIMTQPVYDPELIVAVKEATAHLDIPIFIGIMPL
ASGKNAEYLHNEVPGIQLSDSVRKRMDGLQGEEGRKVGVEIAKELLDTALEHFNGIYLIT
PFMFYEMSVILSNYVWEKSAHRSRYLSRS
>A0A0A3I052|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ureibacillus manganicus DSM 26584|TrEMBL
MGLREALKDRVLTADGAMGTLLYSYGLDYCHEEMNIVRPELIEKIHSEYITAGADIIQTN
TYGANAIKLARYGLESKVVEINEAAIRLAKNAAKPGGEFVVGSIGGIRGVRKSDITLEEI
LAAVKEQAEVLINGDIDGILLETYYVFEELTETLKMLRTMTDLPIIAQVSMQEPGVLSNG
LTLNEAFHELEQLGADLVGVNCKLGPYHTIQAFETIELPERAYLTAYPNASLLDIEEGRV
IYESEVDYFARAALELTNQGVRLIGGCCGTTPKHIEAVKKQLANLKPVEEKLAKPVKEIL
IREPEPTNTEPLHEKVKRERSVIVELDTPRHLEVDAFVEGAKILYSNGADLIMMADNSLA
SPRVSNLAMGAILKQHGIRTMPHITCRDRNLIGLQSHLMGLNALELHDILAVTGDPTKVG
DFPGATSVYDVSSMELISLIKQLNEGISFSGKALRKKANFSVAAAFNPNVRVLDRAVSRL
EKKIEHGADYFISQPVYTKEKIVDIYEATKHLEAPIYIGIMPLTSFRSAEFLHHEVPGIK
LSDEVLERMQACNGDKVREAEEGLAIAKELLDTATKYFNGIYLITPFLRYEMTSQLMDYI
KQLDEETKGVKVNG
>A0A8B5GDK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces viscosus|TrEMBL
MPTVSLELFPPRPGRAASATWGRIDRLLATGPDFVSVTYRPTFVTEPAPGPTERDRGADR
LEPVGDRGDGMPRVRAVQEETNPSEGVLAHVLESSTIPLMAHLTCIGYRKQEAVDIVTRF
LRMGVRRFLALRGDPPAGTRADDVAGELRHADDLVRVIREVEADFFGDGRRHVTIAVAAY
PATSDHIEAIEVLAAKQAAGADLAITQVFYDPADYVALTNAASYAGVSIPILPGVIPLTD
LRRLTRLEALTGVKVPEGLRSSLGSASGAALVERGIGATLDLATALLRAGAPGLHLYTFN
RTRPALDVISHLRLGGILAGAAPDREVRDAVDRGYLQATPGRGPSFLRCGSPGAAASSRH
PVQPHTTITKENA
>A0A0J8RDC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccidioides immitis H538.4|TrEMBL
MEKISNKIAALPEDANYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT
ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPPRSDE
YNLDGEDDSNKEFTYAVDLVRYIRKKHSDYFCIGVAAYPEGHSDESHPGVQDPVRDLPYL
VEKTKAGADFIMTQLTYDLEAYKRFESMLRNHESGVFKTIPIIPGLMPIQSYPRLTRITK
LSHVRVPPEMLSRIEACKKDDEAVKKVGVDILSELVEGIKTIPGTGPRGLHFYTLNLEKS
VSFILERCNLIPPSSEASSDTDSDSVFASGNLQNGLGTAAGKPPLISRRRASSLNSQPHN
RVIVDRADISSQSSITHEASAQGAGMPALNPPHRNTALQISEGMGALGREATWDDFPNGR
WGDARSPAFGEIDGYGPSLHVTANVARRLWGYPTTREDINNIFRQHVSGGLHAVPWSEGG
AAEETGGLSPETITIRPYLLSLIEKRGWWTIASQPAVSGVRSDHPIFGWGPPGEGFVFQK
AFVEFFCSKDDYRSHLKPLLQRYGHDEFAWFATNAAGDFESSTSSSIPVPTGPVDAVFDD
MDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWDEWRRIFPRGSPT
EKLLNRVKEDTWLVCVIGQRFGAGGDPGKDAMEEGKILWKVLAGENVSLQS
>X5US76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSHC426A00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A2H1J7T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. Mu109|TrEMBL
MTGDTSTIARLLRTARLEVLPTDSITAEVRAHAPQHRTVTITASESLGLDATLAVACALR
ADGRRVVPHLAARMVSGRSHLEDIVDRLHAAGVDAVFVPGGDATPGPGAYTSSLALLRDL
EQMDHPFRDIGVAAYPESHPTIPDAEVVRALADKHPFATEMVSNLCFDPDALSAWIRSAR
DRGTALPLWLGVPGRVDAARLARVGARIGVGQSLRFLKGKLGTITRLVTPGGVDTHRLLT
RMSGTLDDPTSRIAGLHLYTFNQVELTEAWLHDTGG
>A0A4Q2FG69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKDLFAHQPNFEVN
>A0A4V2EYE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylanibacterium ulmi|TrEMBL
MVDEGHVPHGGPTDAPRRPIHRPTVSFELMPPRRPEAAPRFWETARRLVAVHPDFISVTY
GAGGGDRATAHRVVSTLLAGTPVLPIAHLTCVGASREDVSAVIDDFLEAGVRAFLALRGD
PPHDQPDWRPPADGVHSSVELVRLLREVEASRAAADPSSALRGAAHPLSIAVATFPNGNP
GAGTTRTQEVCRLLEKQEAGASFAITQLFYEPESYVEFVADARAAGITIPILAGLLPATD
PRRLRRVEELTGVAAPSDLLAALDALDDPEAQHACGVARSVELAQAVLDAGAPGLHVYTF
NKHRPALDLLDGVGLLRREAPDLLEPTTDVRVSASR
>A0A2E6HA36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovorax sp|TrEMBL
MKVTEHLENAKITPFSFEIVPPPRGRTVKDIVDIVKAIQPLNPPWIDVTAHSAGAYYNEK
NDGSVERRIYKKRPGTVGICGIIQNRFKIDTVTHLLCQGFTKEETEDALIELNYLGIENV
LALRGDGLNYNKKVSKERSQNRYAIDLVKQIAELKEGKFVDDIANSQPLDFCVGVAGYPE
KHFEAPNLAYDLKWLKAKVEAGAEYVTTQMFYNNQHYYDFVEKCRAEGINVPIIPGLKIL
KSVKQLQSLPRNFYINFPDDFVEEVMANPDHVVELGKKWAMQQVEGLLNFGVPDVHFYIM
NDTSSVVEVVSHFQKQQ
>A0A3U8MPK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Saintpaul|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1I6XU23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina thermophila|TrEMBL
MLTNFREKLNSGKFLVTAEVSPPKGTRFSGSLEDARYLKGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNVCLMTGDYPSCGDHPGSKP
VYDLDSVQLLQLVRKLDSGIDFAGNKLDGGTSFCAGAVTGIDPGKTIQLIKLEKKVRCGA
EFIQTQAVYDVGMFEEFMEVTSHLEVPIIAGLIPLKSFSMAQFMNKYISGISVPEEIMSR
IKDAPDPVEEGLSIASETIKELMKLSRGVHIMPVGSHKNTPRLLSMAGILGND
>A0A120MZA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter gotjawali|TrEMBL
MKITEHINNAKGKTLFSFELIPPLKGHSIQGLYDAIDPLMEFKPPFIDVTSLREDFIYKQ
HPNGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLQFLGIEN
VLVLRGDARKADASFIPTPNGHNYATDLLEQVVNMNNGVYLHENNEENLKTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKIDMGANFIVTQMFFDNQKYFDFVNNCRANGITVPIIPGLK
PVTGSKQLVNLSKTFHIDMPEDLCDAINACKSEKDVRDVGIEWMINQCKELMAFGVPVLH
FYTMSNAGPTKRIAEAIF
>J0BYW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii WSM2012|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWQTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEDTHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAISDFEISVSAYPEKHPESRDSAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGISIPIVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIDDLVRRGLHEFHLYTMNRSPLVSAVLDNLGLSRRAAKSAGAAA
>A0A414EMV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia obeum|TrEMBL
MATVKLTELMKERQLLSFELFPPKTDKGMENLPGTIEHLCEFKPEYISVTYGAGGGNVGT
NREVCQMVKKAGTVPVTHFTVIKNTKEGIKDQLETYLSEGVDHILALRGDFPRGENSTGG
DFNYATDLVKFIRKEFGDKFEIAVAGSPEGHIACRSLDADISVLKMKQDNGADYIMTQLC
WDMEQFARWQDKIRKAGVTMPIDVGIMPILDQAATINMALSRNGCVMDRELSRLISKYWI
FPNPFDKAPFDDALEQKKEDFKKAGIEYTIKQIDKYRALGVEGIHLYALNKWKDVSEIIK
ESGMRTLV
>A0A1L6J9T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas koreensis|TrEMBL
MSLVLDPGAPLFADVAGDIDVSFEFFPPKTEKMEETLWESIQTLSPLGPRFVSVTYGAGG
STRERTHNTVARIARETPIAAAAHLTCVEATREEIDAVAEEYWAAGVRHIVALRGDPPTA
GAKFVSPQGGYENAAALVAGLRKLHPFEISVAAYPECHPDSPDAAHDLDNLKRKIDAGAN
RAITQFFFEPETFLRFRDAVAAAGINAEIVPGIMPVMSFAAVQKMSAMCGTAVPGWMARL
FDGLDDHPSARQLVSATLAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGVRPTDLS
GEKAA
>A0A072T7P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia tsuruhatensis|TrEMBL
MSFPISFEFFPTKTPEGATKHVQVRKNLYARKPQFCSVTYGAGGSTQTGTFAMVRDIQNE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPQSDLDAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A6A7Z071|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas helleri|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLDQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQAHNFEDDINNFVRKAQAGADSAITQYFFNADSYFR
FVERVEAAGVTIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A5E7EJC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARHLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
HEVKIPAAPHMSCVGDSKDDLRGLLSQYKDAGITRIVALRGDLPSGMGIASGEMRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEEDLLNFVRKANSGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQAFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A6I4FRM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium vitis|TrEMBL
MAHTSSKRDQARPFKLSFEFFPPKSEEMEAQLWATVDELTGWAPEFVSVTYGAGGTTKAP
TLAAVRRLLAETPLATASHLTCVGATREEIAQVVEDFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGFENAAALVKGLKELGDFEISVSAYPEKHPESADLAMDLDMLKRKVDNGATRALT
QFFFDNDIFERYLDKVRAAGISIPIVPGIMPILNLTQLKRFAGMCGTSVPAMLDQRFEGL
DDKPTERASVAAALAAEQIADLQARGIDEFHIYTMNRAPLVNATLERLGLQRSDTAAADR
AGVVA
>A0A349GPH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKIKNMFSENKTVFSFEIFPPKKDSPVDTIYNTLEQLHDLTPDFISVTYGAGGSAAGAST
CEIASVIKNKYNIEPVAHLPCINFTKAEITDILNDFKNNGIENILALRGDINPDIPPKKD
FRYASELIQFIKQNGDFDISGACYPECHIEAENIIEDIKNLKNKVDCGADHLISQLFFDN
EIFYSFEEKARIAGINVPIEAGIMPVVNKKQIERMVSLCGASLPSKFTKIMQKYENHPEA
LRDAGIAYAVDQIVDLITHGVDGIHLYTMNNPYVARKISDSVSGLLNV
>A0A6V8PXN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hakubanella thermoalkaliphilus|TrEMBL
MKSGSNLEKVLSSGHFAVTAELGPPKSCDPEVVEKKAEILKGFADAVNITDNQTAIVRTS
SIATGVIVARKGLEPVVQMTCRDRNRIAIQSDLLGAAALGIKNLLCLTGDHQSCGNHPQA
RGVFDLDAIQLIDMVRRMRDEKKFQCGEEMSVEPRFFIGAAANPFADPFEFQVIRLAKKV
TAGAEFIQTQLIYNVEKFARWMKMVREMGLHEKTYILAGVGPIKSAGAARYMKNKVAGMD
VPGEIVERLQAASDPKAEGIKLCLDIIEQVRAIEGVAGIHIMAIEWESAVPEIAERAGLL
PRPQID
>A0A291FNK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter piscinae|TrEMBL
MALLNFKKRDAGAVQPSSPEVEAFLENYSIEVMPRTAAKVENFRDLLPAGTRVYIAHIEG
TPIEEMVETAKRINAEGFPVMPHFPARIIQDEATLADWIARYQGEADVKQALLLAGGVAK
PHGAFDSSMQLLETGLFDKAGFSNLHVAGHPEGNKDIDPDGSMKNVSDALLWKQKFSERT
DAKMALATQFAFEAKPIIEWADSIKAAGVDLPIHIGIAGPAKLQTLIKFAIACGVGPSLK
VLQKRAMDVSKLLLPYEPTDVIAELAAHKAANPDFNITNVHFFPLGGIKTNATWAINNGG
AAAQPVNSQG
>A0A532EQN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPQRLIDVLNRGTFAVTVEYNPPKGTNISSILENAKQLVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGKDMVGNKLDGSTAFTIGAAVTPEADLVGPVLAKFEVKV
KAGAQFFQTQAVYHPDVFAGFMKQVRPFNVKVLAGILVLRNYKMAEFMNANIPGMSVPTE
MIDELKAAGEKAEDVGVDIAVQTIKAVRPHCDGVHIMAIKATHRLAEIITKAELG
>A0A7I9LBB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKEGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A5N9GE34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MIRCRRGDFPLSRATIFAGTITFYRRAESVGSCWIPSLKIKDILTKTRPVSFEFFPPRQA
EGIPAVLETLDELKQYLPDFVSVTYGAGGSTRAFTEEITFEIKRNTDVEVMAHLTCVGQN
KEELDEVLSRLQEEGVENIIALRGDPPKGTTEFVPVEGGFQHATDLLHHVVSNYKFGVAA
ACYPEGHTESVDLDADLKYVKMKVDNGADFLVTQLFYDNRFYFDFVERARAEGIQVPIIP
GVLPVLNSAQVRRFTTLSGSKIPLDLDKLLDKYADSDHSARDMGVEYATAQVRELWDSGV
PGVHFYVLNRSYSVSRILDNLQIAGHQRQD
>A0A7W1L3X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MEVATLLQDPKNWPIFSAETFPTENWRPIEPILKAVEELLPLGIKAITTTWGALGSPRAG
TAAICRIIHERYKIPTVVHLTIQGKSLPDIEGILRGLDLEGIHNILALGGDPPAGQKDAI
APWMRHRYASDLVSQIANLNEGRWLGPDYDFKKEGVKTRFGIGVAGFPEVHPDEFRDEDG
FDRCLARYIEKLKIKLACGAQYVVCQMVFDAGFFLRFREAAQKAGITAPIVAGVMPFEQW
EQIGRFVGDELRISFPAPVQKALQQASKEDQPRIADDHMASLVEELLEAKVAGIHFYCMN
RSGPTSRVLRRVAR
>A0A5N9E140|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MIRCRRGDFPLSRATIFAGTITFYRRAESVGSCWIPSLKIKDILTKTRPVSFEFFPPRQA
EGIPAVLETLDELKQYLPDFVSVTYGAGGSTRAFTEEITFEIKRNTDVEVMAHLTCVGQN
KEELDEVLSRLQEEGVENIIALRGDPPKGTTEFVPVEGGFQHATDLLHHVVSNYKFGVAA
ACYPEGHTESVDLDADLKYVKMKVDNGADFLVTQLFYDNRFYFDFVERARAEGIEVPIIP
GVLPVLNSAQVRRFTTLSGSKIPLDLDKLLDKYADSDHSARDMGVEYATAQVRELWDSGV
PGVHFYVLNRSYSVSRILDNLQIAGHQRQD
>A0A430TZ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAAGSINSQNTLEIASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLIKEELHA
>A0A1B9PFB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliivibrio fischeri|TrEMBL
MAYSHASHLESLNQNIAELDGNINVSFEFFPPSSEKMEETLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLIAAPHLTCIDASRSELIDIANDYWANGIKDIVALRGD
IPPGGGAPEMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQASRFAKMNNVKIPGWMAQQFE
GLDDDPVTRQMVGASHAIDMTRILSREGVKDFHFYTLNRAEHTYALCHTLGVRPK
>A0A358WE88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKIKDLYTPGRTVFSLEVFPPNKNFPIETVYDAIEGLAAINPAYISVTYGAGGNRANRST
CEIASHIKKKYGIEAMAHLTCINSTRDDVDFMLDDFAANGIENILALRGDNKPDEEPKND
FPHASDLTAYIASKGNFDIAGACYPETHVDAESAEEDIKNLKIKVDAGASHLVSQLFFDN
SCYYDFEKRARAAGIDVPIAAGIMPVTNKKQIERMVTMCGASLPSKFVKMMQKYENDPEA
LRSAGIAYAIDQIVDLISNDVQGIHLYAMNNPAVATRIYNGIKDLL
>A0A073KKT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella xiamenensis|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETNLVAAPHLTLVDASDEELLDLAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPSWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPKAV
>A0A1V2HIV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIVSIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0U1MWM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFDLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPKKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLSKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKISKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A2V8W6F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIFDFNERLKDSILIADGAMGSMLHEAVGTQRCFDELNSTEPEAVFRVHQAYIEAGAQI
IETNTFGANRFKLAPLGLADEVQRLNSRGVKIAREARESAAREVLIAGSIGPLGLGVQSR
HPADHEILDIFHEQALALEERGVDFYILETFSYIEELLLAIDAIRSFSGLPIVAQLTYAE
EGTTYGDLRPANAAEQLKNKNVQVIGANCTLGPQALLPILQELAAVDGLRVSGMPNAGFP
KREGDRIVYPKSSPEYFALFAREAAALGVRILGGCCGTTPAHIRAMAEAVKSLRPAKAHA
VVHSVATMAKPASLSEREPESKFWKKLQAKQFALCVEIDPPKGLSLDRIFEQVGKVMASK
KVDAIDINSGAMARVGMDALIVAGALEARGVETVPHLTTRDQNIIGLQAALLGAWTVGGV
RNILAITGDPPSVGDYPEISGVYEVDSVGLVKVLHRLNQGTDWAGKTLGGETNFTIGVAL
NPVADDLDNEIERFHAKVEAGAHFAMTQPLFDPEHWHAFLKKLGGKPSIPVCIGIWPLNS
YKQALRLNNEVPGIVIPERLLKSMEAAGASARDCGFKVARDMLAWSRTELAGAYLIPPFK
RYEEILEIL
>A0A059DZ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas atlantica|TrEMBL
MSPLSSLQSSDAPSVSFEFFPPKTEAMAARLWETVERLEPMAPNFVSVTYGAGGSTRERT
HDTVRRIAQDTHLRPAGHLTCVGATKEEVLSVAEDYWQAGVKHIVALRGDPPAGMGEKFE
QHPGGFRDSIDLIEGIREHRPDLGRCFEISVSCYPELHPESRGWDAEIAFLKAKQDAGAD
RAITQFFFEPEIYLNFLEKARAGGVTMPIVPGIMLQPNFKGLKRISGLCGSSLPGWLHEL
YDGLDEDTETRELVTANVAADLCRKLSDEGVRDFHFYTLNRAGLALSTCRLLGLKPNSAE
AA
>A0A411LHI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas paucimobilis|TrEMBL
MTNTILTQAEAALAHEEPLFADVGGDIAVSFEFFPPKTEKMDAQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTLAAAAHLTCVEATREEIDQVAQEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPDSADQQADIDNLK
RKIDAGATRAITQFFFSPEAYFRFRDAAAAAGIAAEIVPGILPVSNVAQTRKFAGMCGAS
IPDWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKGFHFYTLNRAELAYAISHML
GVRGKKAETVAAA
>A0A8D1R9C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MDRPKAKGLPAGQCCPSLGVRALEAGISRSSVPPAIRSSAMVNEPRGNGGPGPRCEGSSS
GSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRFD
RMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEVTGY
LHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKGH
PDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACSEMGITCPILPGIFPIQG
YHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFY
TLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQELTSEESVFEVFAHYLSG
EPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGWG
PSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKVGASLGHRVRGRHIYAT
IRQSRSAPPIQALCQTDTQTEPGPCPLRAPSLAREAIRG
>A0A7C8QNR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orbilia oligospora|TrEMBL
MQEKITDKIKALPKDATYFSLEFFPPKTPAGLQNLHARLDRMAKGLRPLFVNVTWGAGGS
TATKSLELASLCQSHGLTTVLHLTCTNMSKSVLDDALENAKLMGIRNVLALRGDEPRQHE
YLDVTEQVRNGSGENEFVYAIDLVRYIRKQYGEYFAIGVAAYPEGYAETAYPVAQDTARD
LPYLREKTAAGADFIMTQFFYDVEAYISFEKVLRNDESGVFKDIPIIPGLMPVQSYQIFR
RTTKLCSVKVPGTISSRIESVKADDEMVKEHGIQVLTEMIGKIRSSTESDGGLPRGFHFY
TLNLEKAVAFIVERCNLIPEIPTSSEVAVEDEDDEGPGLLTVNGGGAAIPRRSRRTSSII
SDPHNRVIVDTVSSARSELQAEAGEAGVPKILDPGSQEGNLAISEGEGSLGREATWDDFP
NGRWGDARSPAFGEIDGYGVSLHRTPTEALKLWGKPTSTKDISDLFVKNSKGELEAMPWS
EDILNPESFLITEELVKMNAKGWWTVASQPAVNSAKSDHPTFGWGPKNGFVFQKAFVEFF
ILDEEWTELKKKLENEGKEDVSFYAGNKAGDFQTNLASDSSLNAVTWGAFPGKEIITPTI
IEEVSFRAWRDEAFDIWSEWQRIYPLSSATSKLLGELKNKLWLVTIIHHDFVNADGLWKD
ILGL
>A0A8B7W030|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Castor canadensis|TrEMBL
MDHRKARVHPAGPCCTSLRMWASDTGSVRLSVAPSISRNPAMVNEARGSGGPHPRSEGSS
SGSESSKDSSRCSTPGLDPERHEKLRDKMKRRMESGDKWFSLEFFPPRTAHGAVNLISRF
DRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRREEITS
HLQKAKQLGLKNILALRGDPTGDEWEAEEGGFNYAADLVKHIRSEFGDYFDICVAGYPKG
HPEAGSFEDDLKYLKEKVSAGADFIITQLFFEADTFFHFVKSCTEMGITCPILPGIFPIQ
GYSSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGQVPGLHF
YTLNREMATTEVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQD
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPTEELLKMWGEELTSEESVFEVFASYLS
GEPNRQGYKVTCLPWNDDPLAPETNLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLRKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQIVEDTFELLNRPARNEQETATP
>A0A3M5BDV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A5C1JMU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHEATHSLFKHHSQVSAL
>A0A2T9ZFP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium megazygosporum|TrEMBL
MKIIDKIKSAQQDDRPYWSFEYFPPKTPQGVINLYERVERMTKLNPLFIDVTWRWGGKSK
DLTQDICINSQTIYGIEANMHLTCTGTDVEGIRHVLENAKRNNVQNILALRGDLPGFTKE
DSAHINDGSCTPMPEYNYDADINAMNQFFSAEQLIKFMRQEFGSYFCISVAGYPEGCNDI
SETEKDIHVLKKKVDAGADLVLSQLFYDVNIFMEWYNKCVKTGISVPIVPGIMPIQSYTG
FKKMVELCNVTVPDEVWSGLSSCKEDDLAIKDFGIKYAITMIKKLFSFGIKGFHLYTLNL
ERSSRLILEGLQFVPIISQPSAPQLNPNTFQDVSIQKPLPWPSCVQTKRISENVRPIFWH
NNVDSYILRTDSWDEFPNGRWGDSRSPAFGELDFNKFWIYPNKKVYSLWGIPKTELDIHD
VFIKYCKGELESLPWSSTPIQAESSEITQNLIKLNQYGYLTINSQPSCNGAKSSDTLHGW
GPKNGFVYKKAYIEFFVHPARFIKLVKLIDEYNMSNGGGNETSNIITYLATSKNTEKLYS
NFNTNQPNAVTWGVFPGCEIIQPTIVEASSFLAWKDEAFDYWKMWSNAYKDKYKETHALL
SGIMDTYFLMNLVDNDYTRSSDAQKNEGPQKSYFYNSSIDQAVSGFVAALASTAVLHPLD
LIKIRLQVKDKEAGSIVGRSVRAFKDITGASSAEIPATASKFQKSIFNLKRFYVGLSPNI
AGNCVSWGLYFGWYNWIKQEISIRQGTASGKKYGQNKQGASFLSAKQHLFASSMAGVLTQ
LVANPFWVIKVRMCQPRELKGSIEYKGVIDGLFKLWKAEGLKGYYKGLVPGIIGVSHGAL
QFMAYEEMKKYLVVKKYNSLQDSSFSYLEYLSMSTTSKLFAAAVTYPYQVVRTRMQSTES
IKYKSVLSTIMIIYRGEGIQGFYKGLGPNIIRVLPGTMITFLVYEKFSAFFRTHAK
>A0A2D9KW43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp|TrEMBL
MSKQPVISCEFFPPKTEKGAQNLLLVQERLAVLKPEFYSVTFGAGGSTQDNTLEAVIAIQ
QRAAETGIDAAPHLSCVGSSKERIRTILQTYIDNGISRVVALRGDLPSGMRDPGDFRYAN
ELVQFIRKETGDHFTIEVAAYPEVHPQAQDAGVDLENFKRKVDAGADSAITQYFFNIDSY
LYFVERCQKKGIDIPIIPGIMPINNYTQLARFSAACGAEIPRWLKKRLEEFYDDSVSMQA
FTTDYLTEFTEKLIKLDVPGLHFYSMNKTQPVLTVCERLGLVR
>A0A3P5ZBW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica campestris|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRANGIQNVLALRGDPPHGHDK
FVKVEGGFGCALDLVNHVRGKYGDYFGITVAGYPEAHPDVIGENGLASDEAYQSDLEYLK
RKVDAGADLIVTQLFYDTDVFLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEVMAALEPIQDNEEAVKAYGIHLGTEMCTKILAHGTKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEEFPQGRWGDSRSA
SYGALTDHQFSRPRSRDKKLQQEWVVPLKSVEDIQERFKELCLGNLKSSPWSELDGLQPE
TKIINEQLVKLNCKGFLTINSQPSVNAERSDSSTVGWGGPGGYVYQKAYLEFFCSKEKLD
AIVEKCKALPSITYIAVNKGDNWVSNTAQSDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFETWSRSWANLYPEAADPSRNLLEEVKNSYYLVSLVENDYINGDIFSVFADL
>A0A6L8HLY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MPDLRSLLSDGRVHVLDGAMGTMLYDRGVFVNVCYDELNATRPGLVEDVHGEYVRAGAEI
IETNTFGANPVKLSSFRLEERTGELNRLAAEIAVRAAGGRAAVAGAIGPLGIRIEPLGPT
SREEARDYFGRQVDGLLEGGVDGFILETFADLVELEQAFRAVRDRCDLPVIVQVTVGEDR
KTTTGASARQAALAAMEWGADAVGLNCSVGPAVVRDGLERMAEVTTLPLAAQPNAGLPRA
VGDRKMYLTRPDYTARYARHLIDAGARLLGGCCGTTPEHIRMISARVASIQPRRTSVRVT
RDVASHAAAHPAPPLAERSGLGRRLATGEFVTSVRVLPPRGWDTTALVEDCRALAAAGAN
VIAIHEDRGGARLDVLATASVIARTCPGAEPLVHYTCRDRKLPRMMSDLLGAAATGLHNL
LLLTGDPPGPGPYPDYRSVVDIDSIGLTNVVTGLNTGVDPSGSEIGGSAGLVTGVALNHT
ARDRERELGRFRWKVDAGADFAVTQPVFDAAQLSGFLAEIEQRIPVIAGVVPLESARQAE
FLQNEVPGVHVPDRVVERMRRAQARGAGRAAAAGVEIAREIAEALQGEVAGIQIAAERAA
AEALLGSWKATS
>A0A450ZQI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. TUN|TrEMBL
MIMNSPGLNTRVFSFEFFPPRTPEGRNKLRTTWQRLSRLNPHFFSVTFGAGGSTQSGTLE
TVLEIQQHAGIDAAPHLSCIGSTRVKIREILEHYLSKDIKRIVALRGDFPPDMVEMGEFR
HANELVEFIRTEAGNRLHIEVAAYPEFHPTAPSASEDLKNFKRKVEAGADSAITQYFYNK
DAYLRFVDSCERIGIHIPIVPGIMPITNYTSLARFSEQCGAEIPRWLDWRLREFGEDMNA
LRTFGVDVTTELCHQLLEAGAPGLHFYVLNRAEPATTIWKNLGLSEIPSSGRSVDQ
>A0A3T0ZSM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas hydrophila|TrEMBL
MGFHSARQVEALNQSLADLSGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPEMYATDLVALLKAEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDDDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQL
>A0A8M1P619|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Danio rerio|TrEMBL
MVNQRADVGWHSKSDSSGASNSGESSRESSRCSTPVPDADRTDRLRDKMKRRIESGDHWF
SLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYC
GLESVLHLTCCNQTKEKITDHLNKAKRLGLKNIMALRGDPVGEDWVEEDGGFNFATDLVK
HIRHEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIVTQLFFRAETFLKFV
KDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIKQVIEPIKDNDAAIRNYGIQ
QAVEMCKVLLASGEVSGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAISAHPKRKVE
DVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQM
WGEELMSEESVYEVFTNYITGQTNRSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGVL
TINSQPNINGKASSDAIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYQI
VNVQGRNITNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYE
DESPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWQVIEDMFALLDSSQVPQQEANEL
>A0A1D8N7T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yarrowia lipolytica|TrEMBL
MSTITKLIAGLKPDEKFFSLEFFPPKTQNGMANFRARLARMAALKPLFITITWGAGGSTA
KKSLDIASECQSMGLDVCLHLTCTNMDPALIDQALEAASKAGICNILALRGDPPRGEEYW
QPASPEFQHAADLVKYIKKKHGNKFCVGVAGYPEGHVDGSDASHQDFHHDLPYLKEKVEA
GADFIITQMFYDDNKFLEYNKAVREFSPLLKNITIIPGLMPINTYTSFVRAARLSHASVP
PAILDRIQAVPTGNDQQVKDIGVEVVSDIVNDVYTKTNKTVRGFHFYTLNLERSVARILE
RSGFLTIEEDCAVEEATGSTASTTPNKTPLRRRSSATHRNRVVDDARHHPDAPKEEPDLT
TLALAIASGEGAVGREAVWDDFPNGRFGDSSSPAFGEIDGYGPSIHVPPARALELWGYPV
DDADLSKLFADTIVGKLPFMPWSDQTLSPETMLIQEQLMELNQKGIWTVASQPACNALKS
DDNIFGWGPKGGYVFQKSFAEFFISPEQWKKLKPLLDAQEDLVSYYVAKSDKLVDTNVSE
RASNGVTWGVFPNREIVQTTIIQEDSFDAWREEAFSIWSEWRALYKKNTASFKLLDKIIN
EYLLVTVIHHDYVEEDGLWELLGSV
>A0A1E7Z409|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Erwinia dacicola|TrEMBL
MSFFHANQREALNQSLTEINRQINVSFEFFPPRTSEMEDTLWNSIDRFSSLKPKFVSVTY
GANSGERDRTHSIIKGIKNRTGLEAAPHLTCIDASRDELRNIAQDYWNNGIRHIVALRGD
LPPGAGKLKMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVLTGIDVEIVPGILPVSNFKQLQHFAAMTNVRVPGWMTSMFE
GLDNDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPRAAVSA
>A0A6A7UK11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHAHATDLLKQVNQFNEGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYTFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAKEVLKCKTDDDAKQLGIEWTTAQVQDLFEHGYNNVH
FFTVSAVDSVKQIAKILF
>A0A821IHH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood1|TrEMBL
MEFTLDDNQTVPDTHKMYDNEINLESMHNANIFKRIESEGANLGARGCSLQPVKYVSLID
KILKRIADNDRWYSLEFFPPRTASGAANLIGCFDRMAAGQPLFCDITWHPAGDPASNKET
SSMMIANTMLNYCGIDTMLHLTCHGATKAAMLEYLYKAKDFGIRNLLALRGDPPVGEDWD
PAKSDFRYAIDLVRFIRQHFGDYFIICVAGYPQGHPDSTSYEDDIAHLKEKVDCGADFII
TQLFFQPETFIKFESDCRAIGITCPIIPGILPIQGYASLRNIVRLAKLDVPKEILACIEP
IKENDEAIRNFGVQACLDLCRTLLDSGKVNGLHFYTLNREFATIEILKRLGLWLEDQPLR
ALPWKKTSYSHARSKENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGVLADYH
LFYMKIDATRDELLDEWGRELTCEQDVWQMFACYIGGEKNHQNKVVRHFPWTDEELSSET
TLIKNNLVDFNKRGILTINSQPAVNGKPSSDPIVGWGTPNGYVYQKAYLEFFTSADNIPA
LQAVLKKFPNVNYHFLNKSGGINETNADDEQPIAVTWGVFAGREIIQPTVVDPVSFMIWK
DEAFSLWTERWGKLYEPESRSHAIIDKIANTYFLVNLVDNDYPQGSCLWQVLDSMFEYQK
LSNQPIDS
>A0A1G7JEV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas carotinifaciens|TrEMBL
MTTISVPQLEEARRALEAPLFADVGGDMEVSFEFFPPKTEKMDAQLWDAIRTLEPLGPRF
VSVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATREEIDQVAEDYWAAGVRHIV
ALRGDPPTLGAKFASHPGGYANAADLVAGLAKRHPFEISVAAYPECHPESVDTVGDIDNL
KRKLDAGATRAITQFFFSPEAFFRFRDAVAAAGITAEIVPGILPVSNVAQTRKFAGLCGA
AIPDWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKSFHFYTLNRAELAFAICHM
LGVRAKPQAVVAAA
>A0A0I9WG98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus cecorum|TrEMBL
MGKPSLSFEIFPPNSMVGEERLIQTLSQLKGLCPDFISVTCSNQQANFIDTTLNVADYVQ
NQLKIPAIAHLPALYLTAKEVDYILKALHQRDISQILALRGDYIENKVQPNDFHYASELM
DYIQEKDSSFKISGACYPEMHPDSKNRVEDILNLKRKVESGCQQLITQLFFDNDTFYRFQ
ESCALSGINVPILAGIMPIINRKQAIRLIQTCQTKVPRKFMAILEKYEYQPESLKEAGLA
YALDQIVDLVTQDAEGIHLYTMNQAETARYIYQATTAIFQNLSHAS
>A0A173RXG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia intestinalis|TrEMBL
MRLTELLNTENVTISCELFPPKQGAQLDNYKKIVGDMAALKPAYMSVTYGATGGTSDYTV
ELANEVRNVNHIPALAHLTCASSTKEKVASVIQELKEKQIENVLALRGDIPQNADFPLPN
QYKHASELIYDIKSQGDFCIGGACYPEGHPESQTLEEDLIHLKEKVDAGCEFLTTQMFFD
NNILYNFMYKALKHGIDVPVVAGIMPITNANQVKRSIALSGSLVPRRFLAIVDRFGSDPA
AMKQAGIAYATDQIIDLIANGVNHVHIYTMNKPDVAGAILENLSDIYVRD
>A0A4P8DX84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter cumulans|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLADFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIKRFCDKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTDSIKAFGHE
VIVKLCERLIVGGAPSLHFYTMNTTDPTRQLVQDLGLA
>A0A0N8TJ02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas viridiflava|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKADLRGLLSQYQEAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQSFG
EEVITEMCERLLQGGAPGLHFYTLNQADPSLAVWNNLKLPR
>A0A350I698|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospirales bacterium|TrEMBL
MKIIEYFEKSKGETLVSFEVLPPLKGGSMQAIFDALDPLMEFNPPFIDVTYHREEFLYNK
RESGYYEKVAIRKRPGTVGICASIMHRYGVDAIPHLICGGFSKEETENALIDLAFLGIDN
VLALRGDARKFETKFVPHPEGNRYAVDLVNQTKDMNDGVYLDCNIENGAKTNFCIGVAGY
PEKHFESPNLNLDLKYLKAKVDAGASYIVTQMFFDNQKYFQFVDACRAAGINVPIVPGIK
PVTKKYQLNSIPRNFFINMPDDLVASVSKADTAEKIQQAGIEWCVHQSKELKKAGVPCLH
YYTMGDTDIIKKIIQSI
>A0A5Q3S6Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria brasiliensis|TrEMBL
MSYAKEINALNNSLCDLKGDINVSFEFFPPKNEQMETMLWDSIHRLKNLHPKFVSVTYGA
NSGERDRTHGIVKNIKQQTGLDAAPHLTGIDASPEELKQIAQDYWDSGIRRIVALRGDEP
AGYAKKPFYAEDLVKVLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVTVGIDAEIVPGILPVTNFKQLGKMAQVTNVKIPNWLARMYDGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHTLGVRPLPQAA
>A0A7D5SZC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas veronii|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLTKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A7X3J3W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia thailandensis|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKAVCERLGL
>A0A263HGH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus seminis|TrEMBL
MSYAKEMDTLNQHLVDLKGDINVSFEFFPPKNEKMETILWESIHRLKSLEPKFVSVTYGA
NSGERGRTHCIVKRIQQETGIIAAPHLTGIDATPEELRVIAKDYWESGIRRIVALRGDEP
PGYDKKSFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDINSYLRFRDRCASIGIDAEIVPGILPVTNFKQLLKMAALTNVKIPSWLAKMYDGL
DQDQTTRNLVAASVAIDMVRVLSREGVNDFHFYTLNRSELTYAICHILGVRPNL
>A0A8B7I992|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apteryx mantelli mantelli|TrEMBL
MDTRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVNYCGLETILHMTCCNQTK
DEITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVEGFNYAVDLVKHIRNEFDDYFDICVA
GYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLKFMKDCQAIGITCPIVPG
IFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMV
HGLHFYTLNREVATTEVLKHLGMWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYI
YRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVF
TCYITGEPNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNINGKPSTD
PIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNYHIVNVKGQNITNAPDLQ
PNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDN
YYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A154ML48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis regifaucium|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPEGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTLRTLHTTIKLSGAPAPRRLLDRLEPLA
DDPKAFRAAGIDTVTELCERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A6V7CTI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. vitians|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDT
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A0N8GVY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio splendidus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASRDELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A5A9E2Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter portucalensis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A143PDI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus condimenti|TrEMBL
MSRFLQTLKENVLVADGAIGTILYSEGIDTCPEAYNITHPKKIEQIHRSYIQAGADVIQT
NTYGANFEKLQTFGLEHQVKDITRAAVRIAKKAANENTFILGTVGGFKGVKQNELSLSTI
LYHTDIQIETLIDEGVDALLFETYYDLNELLQVIRATKKKYDIPVIAQLTASNTNYLQDG
TEINEALKQVEAEGADVIGLNCHHGPHHMQQSFTHIELPQHALLSCYPNASLLDFENSSI
KYSDNASYFGKIAKSLVKEGVHLIGGCCGTTPEHIHYIKEAVEGLEPINEKKVIPIRRKS
NHPSIPVQKDNLTTKVKSGPTVIVELDTPKHLDTTKFFANVTKLDKANVDAITLADNSLA
TVRVSNIAAASIIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKV
GHLPGATNVYDVNSKGLTELAVRFNQGLNIDGGALKTTTNFNIAGAFNPNVRKMEAAVRR
LDKKLDSGMNYFITQPVYTVEKIQEIAEKTAHLDSPFFIGIMPITSYRNAQFLHNEVPGI
TLPEDVLEQFEAVKDDKQKTKELSLKICRRLVDEVTKHFNGLYLITPFEQVDYSLELATY
FKTKTESNQEAII
>A0A1A6L9F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio splendidus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A1R0FST7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter braakii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIAQDYWHNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A0T9UZC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia frederiksenii|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLRDIATDYWNSGIRHIVALRGD
LPPNSGKPEMYAADLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFE
GLDDDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A1R7Q905|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A5N7C1E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petromyces alliaceus|TrEMBL
MHIKDKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAADGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSTF
IVTQMFYDTDIFIAWVKKCRAKGINVPIIPGIMPIQTYSAFIRRANWTKIHIPEDWLEAL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGLNHLHFYTMNLAQATQLVLEELKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIRDLSHIFVRYLEGQLNRLPWSDTPISSEANSIKANLIE
LNNRGLLTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLVPPYLLDELIARIESNE
DLTYHAISKSGELRTNTRDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHDATSPSRKLIQGLVDNWYLVNIVNNDFHNTSVLFELFKDLHVRDFDVEVTANIDSKS
QENGTADATEIAVKN
>A0A356S727|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDSEYSPFSIEFYPPRNAEGESRLDAVHAELAKLNPDYFSVTYGAGGSTKTGTSKLVMKY
QAAGSQVAPHLSFGGTDEQEVLELLQTYKEAGIKRIVALRGDIPSGSGAPMHYRYANELV
KFIRKETGDYFHIEVACYPETHPEAKNFSDDVAFFKQKVDAGANSAITQYFYNVDAYFRF
VDYCDSQGINVPIVPGVMPITNFDNLKRFSAKCGAEIPLWLGKRLEDFGYDVTGLKQFGQ
DVVTELCYDLLQGGAPGLHFYSMNLSKSVSQIWSELGLQDRNT
>A0A2E9ZGS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPGSNSRQFSIEFFPPRTEAGETKLDAVHASLAKLNPDFFSVTYGAGGSTRTGTQKTILR
YQSLGSQMAPHLSFGGTDTSEIVQLLDIYRQIGVKRLVALRGDIPSGSGAASQHRYANEL
VAFVRKQTGDFFHIEVACYPEIHPESSSYTADVAYFKAKVDAGADAAITQYFYNADAYFQ
FVDYCTRAGIEIPIVPGIMPITNYGNLARFSANCGTEIPRWLAKRLTGFGDDVQGLRSYG
IDVVTDLCQRLLDGGAPGLHFYSMNLAASVSQIWTNLALSPRK
>A0A7Y1H775|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas proteolytica|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCETLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A537LW20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrabacteria group bacterium ANGP1|TrEMBL
MKSHPFLARLEQGVLLADGAMGTLLYARGVAFDQCFDELNLSRPEVVRQIHLDYIASGAE
LIETNTFGANRFKLGQHNLAHRVAEISHAGAALAREAAGTANRHVFVAGSMGPIGRPMAP
LGAITPEDVRSAYAEQATALVEGGADVLILETFTDLNELLEAVRGVQSATAVPLIAQMTF
TQDGKTMLGHEPREIVRALEQMDVDVIGANCSVGSQGILEVLQQMAAGVTRARLSAMPNA
GFPAYVGGRYIYFSNPAYMAGYAAQLAAVGVRVIGGCCGTTPEHIAAMRRALAEPVERAV
DLTIPADLRSSRPAESEPVARPQDPTPFAQKLGRSFVITVEIDPPRGVHDRRELDGCRRL
NDAGVDVIDVADNPMARLRMSPWAMCARIQAEVGVETVLHFTTRDRNLVRLQSDLLAVHA
LGIRNVLVLRGDPPQMGDYPNATAVSDVKPSGLVRLIKKFNQGHDVAGNAIGTPTGFTVG
VALNLAAPDLDKEARILERKVAAGADFICTMPIYEPEALDRFERIMGGLPVPALLGVLPL
VSHRHAEFLHNELPGFAIPAWVRERMHQATDARQEGIRVAVQLMEAVRLRVGGVYLVPSF
GRYDGVLELVRLARQPAKT
>A0A5S6Q6Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichuris muris|TrEMBL
MEVPSCNSRLTDHAEDVEPRKPLRQRLRERINSGEVFFSLEFYPPHTEAGLKALYRSVEQ
FANAGPLFVDITWNLRSDPGSEKPTSTTSVAYHLLNTYLLDVVTHLTCLDSTTTQIESHI
ERIKNIGVRNIVALRGDKPENLSEPMMTYKHASQLVQLLRSNCGEYFTIAVAGYPLMHPE
SPSLEDDLKFLKQKVDEGADFIITQFFFNPSTYFTFVRRCRGIGIDVPIIPGILAIHSYD
AIKKICKMSGIVLPDSIEALLEPVRDIPSLVKEIGVDIAVQLSLELLNDKQYPAPGLHFY
TLNKLSPTEEILRQIGLWNTVPTRILPWRVNRTQIIRRTEAVRPIYWKNRPMAYICRTQR
WTNFPSVTWNDKPNSEMSNLDDYKLFDPLQRISKVNLRKMRGDNLCSVEQVNKTFADMLF
GENKDGVVQYFPWSERAVNGEALSIKEELLWCCSHGLLPINWQEAVNGVSSSDPLFGWGE
PNGTIYQKGYIEFFADSPKADKILHTVRKYPRISYHLVSCNNSYEETNAPTSVTANVVTW
GEFPDGKTVQPYVTQPQAFRQWTEEAFHQWSTWGDVYDATAGARHLLKTISASYILVSLV
DNDYLNPCCLFDMLKEALGDRAEGSEMATNDFSKS
>A0A6U3A3Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lotharella globosa|TrEMBL
MNGHLQFSEKKNKRDLSDIKGGTSTPRSGPSEKIINKINRAVNERRTFYSFEFFPPKTEA
GVMNLYNRIDRMVAKYEPMFVDVTWGAGGSTAKLTLEISSNVQNYCATDVLMHLTCTNMP
RDSVKDALDKAKEAGIRNILALRGDPPHGQDTWEKCDKGFEHALDLVKFIREEYGEYFGI
AVAGYPEGHISSPNLEEDIKHLKLKVDAGADFIMTQLFYDVDLYIDFVKRCRQAEITVPI
LPGLMPINSYNAFKRMIAYTKATVPKEIIAAIEPIKNNDAMVKAFGIELAKKMSQKILRT
GLTPGLHFYTLNLEKSVTKILGGLGLARLPSKGVRPLPWKQSCATRRRNEDVRPIFWANR
PYSYLSRTISWDEFPNGRWGNSTSPAYGELYDYHLMGLKSSSVRDRLRMWGGEVQSEQDV
FDKFADYIEGKIARLPWCETGIMLETLPLKQRLMAINKTGFLTINSQPRVNGARSDDEVV
GWGDPDGYVYQKAYIEFFASPERIKSLKALASRKEYKTLSYHAVNAKGDQFSNYTDKNAV
NAVTWGVFPGREVLQPTVVDMDSFRVWKDEAFALWISQWRSIYSSGSASWEIIQKIHDTY
YLCNIVENDFVKGGLDKFMDELAGYTPAEKSASTNTEEKSKTEKA
>A0A5I0L5C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Agama|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>D4A7E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rattus norvegicus|TrEMBL
MSRNPAMSNEARRSGSPSPRSEGSSSGSESSKDSSRCSTPSLDPDRHERLREKMRRRMDS
GDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIAST
ALNYCGLETILHMTCCQQRQEEISGHLHRAKQLGLKNIMALRGDPVGDHWEAEEGGFSYA
TDLVKHIRNEFGDYFDICVAGYPKGHPDAESFEDDLKHLKEKVSAGADFIITQLFFEASS
FFSFVKACEDIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQTIKDVIEPIKDNDAAIR
NYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDPRRPLPWAVSAHP
KRREEDVRPIFWASRPKSYIYRTQGWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRE
ELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWNDEPLAAETSLMKEELLRVN
RLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELR
VNYHIVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQW
GKLYEEESPSRMIIQYIHDNYFLVNLVDNEFLLDNCLWQVVEDTFELLNRHTTKKEAQAP
>A0A728LML5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 58:d:z6|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6A8N070|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAERFSTSERVFTVEFPSIDGGNLSAIKSRVDHLLPWFDAANATDSPAAHAHASNVAIAI
ALQNFGLEPILQVVCRDKNRIAIQSDIMGAALHGVRNIELLTGDDVTAGDEPEARRVFDV
DSAQAIKIAATLKGGSYLSGRKFSDAPDLFIGAVENAAAPPLEYRAERVTKKVNAGAKFF
QLQICFHGDRLENFTQAVNASHPTLPLLPTIVLVKGARPLKFMNEKVAGIDIPTEVIAQV
EQASDPKEAAYQLARAQAEHALSLPGVRGLHFTDFCHDDSLVRLMRDLGVTPRPTGSH
>A0A484RD20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|plant metagenome|TrEMBL
MSLDTEKAAISLEFFPPRDLAAQERLVRTAKQLLAVQPRYVSVTFGAGGSTRDGTSGTVR
TLRNLGCDAAPHLSCIGASRDELRQILQGYRDEGVRRVVALRGDLPSGMGGDAGELRYAA
DLVAFIRAEFGDAFHVEVAAYPEMHPQAESPSADLRHFADKVAAGADSAITQYFFNADAY
FDFLDRTQALGVSVPIVPGIMPITNNTQLTRFSQMCGAEIPRWLRLRLAEFGDDKASLRA
FGVDVVSELCQTLLDNGAPGLHFYTLNSADAPLAIWRQLGLERAAA
>A0A7W6ZCM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium etli|TrEMBL
MALKNEAQARDIGISFEFFPPKSEEMEGQLWNTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVSHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRKAGISIPIVPGIMPIQNLTQLKRFAGACGAIIPGFLDKRFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIRDFHLYTMNRSPLVSAVLDNLGLSRRAAKNAGAAA
>A0A2X3V3J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTFAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A2G9EJR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium pseudoperiodonticum|TrEMBL
MKIADIYKGKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIADRIKNQNGVESVAHLTCIGAKKEEIDRVLEDLEKHNIENILALRGDYPVDRELEVGD
FSYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A3A8I3L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus exercitus|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTVEELAPLEPGFVSVTYGAGGSTRDRTV
ELVTHIKKQSGIEAMAHLTCVGHTRDELRDVLRRLDAAGIENVLLLRGDPPQGQTKFEPV
PGGFRYAEELVRFVREEDFNFCIGGACYPEGHVETASREDDLQHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRVGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVGALKGRS
>A0A5A8DZR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cafeteria roenbergensis|TrEMBL
MAGAPRKVSDMMADAIAAKTPFYSFEFFPPKTDVGRENLFLRIDRMSILEPIFVDVTWTT
AGDGKDSRDGTFSVCEYAKQYAGLTPMLHLTLTGLTRADLLRQLQRARDAGIRNILALRG
DPPKGATEWRPCENGLSRAEELVRLIREEHGDWFCVAAAAFPEGYKEPSVPRGGDRPRAG
DDGDAAAAAAGSADGAEGAEGAGGAVDAAARDVADRDAAVAAAAAKVAAGAEVLLTQCVY
DVEAYSGFVAACRAAGVPESVPIVPGVLPVHGYEAFRRMTAYTGVNVPAELQDALDAAAV
SGDDEAVRREGTARVSALCRALLEAGAPGLHFYTLNLEMATRAILKDVGLCRGAEARRLP
WRPLGDGPGALTQVRPIFWANRHRSYVERTRNWDEQPTGRWGDGQSPAFGALSESHFGGP
GAAQGTSEERRAIWGEAEALDGEGPVLEVFARYLEGQVPRLPWCDQALLPETAPIRERLV
RLNRSGFCTINSQPRVNGARSDDPHVGWGGAGGRVYQKAYVECFCSPARLAALMEAAPAH
PSITFTAVDASGNLYTNCKRRGVQAVTWGVFPGKEVLQPTVVDEAAFLAWKDEAFQLWAS
VWADAYPEDSPAAEVLHGIATSWYLVHVVDHDFVAGDVFRPFEAATAALRIASD
>A0A0N4V9T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobius vermicularis|TrEMBL
MNKETSSSSIAAGCLDYCGMETMLHITCAQYTKEQTLRHLEQSKAVGLKNILALRGDLPQ
SSGLKVVPKFRALDMIRWIKEEFGEYFTIGCSGYPTGHPEAPSYKADLQYLKAKVDAGAQ
IIITQLFFEAEEFEKFVRDCREIGINVPIIPGIMPIQSYESIRRITTLSKLTIPDWILKE
LEPIKQDDDAVRRYGIHCAVELCRRLLANGSAPAIHLYTLNREASCREILQTLGLWVKMP
QRALPWKSFGGNHPLRCKEDVRPIFWSTRPKAYVFRTRDWDDFPNGRWGNSSSPAFNDLA
DYYLFHLKGLPTKEEQLSMYGYNLDSLESVQKVFVNFITQNPNENGVKVTRLPWNEQEIG
TDPETSLIKDQLVWCNEHGILTINSQPPVNGTPSADPLVGWGRPGGYCYQRAYLEFFTSK
ENAIALSQVLGLQTRLSCQIINHDASFDWTNAESTTPIAVTWGVFPGMEIAQPTVVDPLS
FRAWKDEAFAAWLNWAQAYPEGSRSREVLEEIHDGFCLVTLVDNDYPKTTVIFDVLKELI
SESDEN
>A0A7Z9K371|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MAVSFEFFPPKTEKMVERLWRSVDRLAPLRPRFVSVTYGAGGSTRDRTHAIVAHLRRNTD
LEPAAHLTCVGASVEEVNAVVRDYYAAGVRHIVALRGDPPEGESKFTPHPEGYDGSVELI
SGLKTIADFEISVGAYPEPHPDSRGMQSELDYLKRKLDAGATRFITQFFFDNDCFLRFLD
KVRGAGIEAPIVPGILPVTNFQQVARFSSMCGASIPDWFGSRFDGLDDDPSTRQLVAAHT
AADQCFGLLESGINEFHFYTLNRADLVFAICHMLGVRAGPTAATGAD
>A0A182HDZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aedes albopictus|TrEMBL
MHQLTVESDPPNSIEYAKGRASPAEAMHSHENSRNLKQVIQQWTSSERLSYSIELIPKED
FVLDLSRLNPQPMFCSLPWISDNNLQYQRFVDTPMLKMTAKIVPHCSVMNHISCYNITET
QVDKFVEMGNWNLFVIRGDTVGENQRFKHSSDLVEYLRSKNNPEMTIATGGYPYVHPESP
SLDYDVKYLKQKVDLGVDFVLTQTLYDAASYLQYVDECRRAGITVPIVPGIFLPSSYDQL
ETVLNLTRVNPPADVLAMLHSHALDEPDVFEAFVVKHFVELVRTLRQERPHEVKLVHFFT
FNRLGLLRKVLDKIADLF
>A0A3V4R1G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATGDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDIYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7T4SR02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYADDADAVRAFGADVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A5N0G2K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYLAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMIKHKVAGIVITPHMLKVLAGEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKKTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A336QZU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWHNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A5I6YYM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Brandenburg|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4U1LVN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia marina|TrEMBL
MSASEHPSGISFEFFPPNTEVGREKLMGVRDRLAALDPAFFSVTYGAGGSTRERTFNTVQ
SVRSSGICTAPHLSCVGSDRGELREILGEYREQGIKRLVALRGDLPSGMGARSELRHANE
LVEFVRDETGDHFEIAVAAYPECHPQADNYRMDLENFARKMNAGADIAITQYFFNADAYF
HFVERARDLGIQQPIIPGIMPITNYTKLARFSDSCGAEIPRWIRRQLESYADDSESLQAF
GTEVISRMSQRLLDGGAPGLHFYTLNQAGPCLKVLENLGISSR
>A0A0F0MPM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter hormaechei|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMFAADLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A0H3NI97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium (strain SL1344)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A496YIS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSFEKKIRSGEFVVLAEFEPPKGADFSEMLSNANNVKGRIDAFVVPEMANAVMKASSLGG
CLFLQTHGFETVLQVCCRDRNRLALQADILSASALGVPNLMAVSGEDISLGDHHQARAVY
DINLMELLEAIRQLQAGKDMAGIELKGAPSFFVGSTFNAGAPGGLLDIELEELDKKVGAG
VQFVLTSAIFDLTHLERVIKRIDTDKVVLIPKVLLLKSAGMARYIDRNIKDISIPGDLIQ
SIQKSPDKTRQCIKIAAELVKEIKAMGLPGVVISTIGWEDKLPQILDESRIL
>A0A2E4F137|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MHNLVESYTSADTPLVICDYSPPRSPRQLNVESIEKLPIDYFSVAYNPGRSPRVDSITVA
RSLQEKTGKPAIFTIATRDMNKIAIQSQLLGAYMAGLSHVLLLGGDSLSQEELALGATEV
RNYKPTELIASTAELSAGWDYRGKPIQPPPTFCIGAALDTTRDLTKEVLLAEKKIEAGAN
FFISQPIYEITEYQNFLTAYRKITGKELSVPVFWGLQMLTSDGPIFGNPPKAFLRDLEEG
ISSEVIAKKQFAEMKTAGIKGVYLIPPISANGRRSYSSITLLLDN
>A0A358QPI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRVADLLQARRPNFSFEFFPPRDDEGVAALFETISALRELDPGFVSVTYGAGGSTRALTV
DLVERIRRELEITPVAHLTCVGSTRAELHAVLRRIVDAGIENVLALRGDPPRGKTAFTPE
PDGLAHGSELVALVTGGYDLCVGAACYPENHLESASRADELRWTREKVGRGASYLITQLF
FDNHAYFDFVAAARAAGVTVPIIPGIMPITSVSQLHGFIARLRVEIPKKLLAAFESRRDN
PQAVLELGVAWSTLQCAELLGAGAPGIHFYTMNRSPATRAILSALLAARPWERPG
>A0A6B0ZTL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MTRIADLLGAQNTLSFEFFPPADEVAAKQLEKTLDELAGLSPSFVSVTCGVGGDGHDRTR
DIVTDICRDRTFPAMAHLTCVGHTREGVAALLDDYAAAGVANILALAGDPPDGSAISGDF
HYASELVEVIRDHPADFSVGVAAHPEVHPRSTNRASDRQHLAAKLSRADFAITQFFFDPA
DYVQLCEELADLGCQQPVIPDVMPVIWPKSIRRFADMNGSTVPEDLFTRLESMPAPDRIG
AAAESAAKLSQTLLDAGAPGIHLYTLNRPEASTQITELLNL
>A0A1C3W777|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus alkaliphilus|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYREGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVRAGADSAITQYFYNADAYFRFVD
DVRALGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A0V8EKU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVVNRNQILRLLKNCNTPLPAKFIRILEKYEHNPLALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>A0A5H6T899|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella abony|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A415PT78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides stercoris|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEKNGYHHAVELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTNEILKCKNDAEAQQVGIEWCVQQCKELMKYHIPSIHF
YSIGAVDSIKEVAKQIY
>D4N1A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerostipes hadrus|TrEMBL
MKISEILKNKSTISFEVFPPKNKEGNISSIYSTIEGLAKLSPDFISVTYGAGGSTKGKTV
EIASVIKHEYGIESVAHLSCISSTKEDIKYECERLKEAGIDNILALRGDYPADATNFDPE
NLEFHYASELNEFIGEHFKGQFCLSGACYPETHQEADGFKKDLEALKKKVDAGAEYLVTQ
IFFDNDYYYRLVREARKIGITVPILAGIMPITNAKSLIRTTKMCGCTIPYQLSTMIEAHY
DNPEAMKEIGINYAAQQIIDLITNGVDGIHIYTMNRAETAQRVFDSIPAVLKELN
>A0A4U8J744|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Chester|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J6LT14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MKIADALKAGPCYSFEFFPPRSEEAERNLATAIRELAPLAPAYVSVTYGAGGSTRDRTHD
LVVEILRDTGITPMAHLTCACHSRQELVDVVTRYRDAGIENILALGGDPPADSDQPPGEL
KYASELVDLIRGVGDFSIGVAAHPEPHPHSPSIEEDRRRTAEKLSKADFAVTQFFFDARH
YFDLVESLHELGVDKPVIAGIMPATSMRSITRMSELQGSEFPKDLAAKLEAAEPDGPEAV
HRVGVEEATRLCRELLDGGAPGLHFFTLNRSMATREIYEALGL
>A0A1G4VPR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium jeikeium|TrEMBL
MASIRRQVAVSQSLSLNTPGRVPFSVEFMPPRDDAAEERLWNAAEAFHDLGVSFASVTYG
AGGSTRERTLRVAERLGTKPLTTLVHMTLVQHTQEELQDMLRTYASLGLTNLLALRGDPP
GDPNAEWVPTPGGLSYASELIELIREMPECADFDIGIASFPEGHYRTGSLEQDTEYTLAK
LRAGAQYSITQMFFDVDHYLRLRDRLAKADPEHGQKPIIPGLMPITSLRSVRRQMELAGA
ALPPKLEKRLLDAAAGDEVANRDAIREVGIEVTTEMAERLIAEGVPDLHFMTMNNVRATQ
EVLHNLGMAPAWGPGLGHDMVR
>A0A0D1VZQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aneurinibacillus migulanus|TrEMBL
MSMPQENIKTYLKDNLLIGDGAMATWLYRLGVPIGVCYEELNLSNPEIIGTVHRSYYEAG
ARFIQTNTYGAHRDALARHGLQDQVQRINRSAVQVARRAVGDDAYVVGGIGSINAGRVRN
MEQIGTYGDQYEEQASALLSENVDAILLETFLDVDELLLALDVIRPLTDLPIIAQLATIE
VGRTRDGHTLTRAFAELVKAGADIVGLNCRMGPAEVLRSIEGAVVPEDTPLSVFPNAGRL
AMSDGEYSYASVPQYFGDSALRFRAQGARLIGGCCGTTPEHIRMMAQVLAEREPLPRVNP
EVQIEEAQTPIRVVPPVRPKGIVDTVTQRHTVIVELDPPRDLDTEKFLQGTAELRDAGAD
AITLADNSLATTRMSNLALGSIMKTKLSAEPLLHIACRDRNLIGQQSHLMGLHALGINQV
LVITGDPARFGDLPGASSVFDVSSFDLIRMIKQLNEGYSFSGKPLQQRANFVVGAAFNPH
VRQFDAALRRLEKKVEAGADYIMTQPVYDQETIELIYQGTKHLNIPIFIGIMPLTSSRNA
EFLHNEVPGIKLSDEARERMSRYEPGEEARREGISIARELVDMAMDRFKGIYLITPFFYY
QMTAELTRYIHEQSNLGLSAQK
>A0A7Y2T9I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriaceae bacterium|TrEMBL
MRVIDHLEKAKEPLISFELIPPKRGGDIHDILNVLDNITKFKPPFIDITSHSAEVIYEEL
PDGIRKKVKRKRPGSLGICALIQNKYNVDAVPHILVKGFTREETEDFMIELNYLGIDNIL
AVRGDDSGYEKPIPLGRSANQNALELVEQIVKMNNGIYLEDSLLDAKPTNFCIGVGGYPE
KHFEAPNLKADIKFAKQKIDSGADYIVTQMFYDNNYYFKYVDECRKMGIDAPIIPGLKIL
TSKAQLNSIPKDFIVSIPSALSDEVEAAKPEEVLNIGVEWAASQVRELLDKNVPSVHFYV
MLNSRPITMLMESLNLFKKVF
>A0A6J7TN45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSVMREKLENSNETVFTAEFPSIDGAGMAKVEKSAARLAPWFDAVNATDNPAAHAHASNT
ASAIAMKMHGIEPIMQIVCRDKNRLAIQADMMGAALHGIENISLLTGDDVTAGDEPETRR
VFDIDSTQAINIARILTTGQYLSGRKINPAPDFYISAVENAAAPPFDYRIERALKKYRAG
AKYLQLQICYHPDRLEKFCAGVAKIAPDLKLIPTIVLVKSAKPMGFMNDKVPGIDIPLDS
INRVASAADQADEAYKLTLELAKHALSLPAVRGLHVTDFRHDDSLDSFMYDLGQKPRN
>A0A1Z3VKX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium jeikeium|TrEMBL
MPLSPGRQVTIRQALSMPSAGSIPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFASVTY
GAGGSSRDRTLRIAQRVSRQPLTTLVHLTLVEHTVDELREILRSYLSAGLTNLLVLRGDP
PGDPLGPWVETEGGLHYASELIELIKAEPEFEKFEIGIASFPEGHYRSPDLDHDTQYTLA
KLRAGAEYSITQMFFDIEHYLRLRDRLVEADPVHGAKPIIPGLMPITSLRSVRRQVELSG
AQLPSDLEERLIKAADGDEQANKDEIRKIGIEFSTNMAERLIAEGVPGLHFMTMNFARAS
QEVLHNLGMAPEWGTGQDMLRGGF
>A0A6J6LGA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTRIADLLATGRTFSFEFSPPKSADGSMSLGRTIAELEPLAPSFVSVTYGAGGSTREHTR
DTVLWVQRETSIPPMAHLTCVGHTHAEIADIIATYVDAGIVNVLALAGDPPKNPADARPS
DYTYATDLIEHLREISDLCIGVAAHPEGHPRSPDLATDRRLLAEKMKVSDFATTQFFFDI
EHYVSLVNDLADLGVDKPVIPGIMPVTNIGQVERMAQLSGAAFPDWLRARLEAGTSPEHV
RQIGVEAATQLCADLLDAGAPGLHFYTLNKSTATREIYAQLGLPVA
>A0A3D1ZQK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium sp|TrEMBL
MHSPLFSLEVFPPKRTSPVGTIYDTLDGLQGVDPDFISVTYGTGKSSDRTLTARIAHTVG
EYGIPCVAHLTAQYLDKDDVDEALDMFSQAKVLGVLALRGDRVEGVEPAGVFEHASDLAA
YIRVRHPEMKLYGACYPEKHPQAATLKSDIDNLKKKVDSGVTHLISQLFYDNEDFFRFLD
AAHAAGIEVPIEAGIMPVMNAKSVLRMSRMCASRIPGKVQRIIDKWGDDQAALKEAGIIY
ASEQISDLVAHGVDGVHLYTMNHPSVSRRIWFNVKPLFV
>A0A2D5XWE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MATSIETIQSAASNWSIEVTPTGATKIESFRDCLDPGTTVNVTFLPGTDPADTIAVCERL
HNDGMRPVPHLAARSLRDADQLDELLSAYTARCGVEEVLCIGGGVDSPVGGFDATMQVLQ
TGLIQKHGIRHIGVAGHPEGSPDISNDEIAEALDAKNALAKAEGLNLYIETQFCFEADIV
LEWEKRVRAAGNALPIRIGIPGPATIKTLFRFAQISGIGPSMRFISKQAKNVAKLMTVQS
PHLLLTGLAEGMAADKECLIRHFHYYPFGGFARTATYAGAIANGRIEMLPKGGFDVIDG
>A0A3S4CZD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAHDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A439QPK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MTALQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A412INT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides cellulosilyticus|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYDTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELAYEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A174V539|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides uniformis|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEGLTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A1I7V5Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loa loa|TrEMBL
MHVIMDSVTDDNGIRTDLTNSNFKFVIDSPEITNQAAISSDPVIPQACGKKWSESRTDWA
TNGTYVPLRDRIKKRIARGIPFFSLEFFPPKTANSVANFFARLDRFREGNPMFVDIAWHF
GSDPGNINNETSSSSVAAGCLDYCGLDTMLHITCCPYTKEQSIRHLEQSKALGLKNIFAL
RGDLPRQDENPLLYKYRALDLIRWIKEEYNDYFTIACSGYPAGHPEAPSYRADLLYLKAK
VDAGADFIISQIIFDGKIFQSFLRDCREIGITVPIIPGILPIQSYESIRRIAELSQLIIP
DSILASLEPIKNDDDAVRNFGIRHAVDLCQTLFTSGSATSVHLFTLNRETSSREILQQLG
LWPRSPVRALPWRSFGENHPIRCKEDVRPIFWSMRPKSYIFRTREWDEFPNGRWGNSSSP
AFNDLKDYYLFYLKGQPTKDEQLRMYGERLETLADIQKVFVNFITQDNNENGVKVSQLPW
NERHDGIRAETSLIKDQLLWCNANGFLTINSQPSVNGAPSTDPFVGWGKPGGYCYQKAYL
EFFTSQANAEVLWSLLPSYSRLNCHIVNHDATIDWTNNETTMPIAVTWGVFPGSEIAQPT
VVDPLSFRVWKDEAFSAWLNWSSIYAEGTSSRCLLEKIYNEYCLVTLVDNDYPKPTIIFD
CLAQLINR
>A0A530A5B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAPRDQVDAVIREFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A061CWR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas oleovorans|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFG
EQVITEMCERLLQDGAPGLHFYSMNLAGPSLAIWNNLKLSR
>A0A5J4SHF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
MRIIDLIHNSKRTAFSFEILPPLKGTGIEKLYDTIDTLREFDPQYINITTHRSEYVYADC
GNGLYQRSRLRRRPGTVAVASAIHNKYHITVVPHILCSGFTKEETEYVLIDLQFLQITDL
LILRGDKAKHELVFTPEENGCLHAIELQEQINHFNQGLFIDGTKAKAPAFPFSYGVACYP
EKHEESPNIDSDIYWLKKKVEAGAEYAVTQLFYDNNKYFSFVEKAKKAGVNIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEALLSELVKCKNDSEAQQVGIEWCTAQCKELIAHKVPSIHF
YSVAATDSIKEVAKRIY
>A0A439TKM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKITAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A7Z9KY09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MSRYEQFADALQSGVLVCDGAMGTELYNRGISFDLCFDEFSISRPDLVRSIHEDYKFAGA
QILLTNTFGSNIYRLSSHGFEEKVTEINAAAAALARSVAKESSYVAGSIGPLGKRLAPVG
QISIEDAQDAFAEQMTALANGGVDLFFLETFSDLHEVEAAMAAWKRVASEIPLVAHMTFT
DEGKTLHGYKPEEVAQAMTEMGALAVGANCSVGPQGLMEVIERMLRVPDIKLSSQPNAGL
PQFHHGRYVYITSPDYMAESAKQFVQMGCHLVGGCCGTGPAHVRAMRSMVEGMTPTRPKR
QLHIDASDPEIEIRRPPTGGQRNTLREKLDAGEFVSSVEIDPPKGINVEKLVRGAELCRS
SGVDCINIADSPLARARMSHTALATIIRREVDIEIILHMSCRDRNLIGLQSEIMGAYALG
IRNILCVTGDPPQVGDYPNATGVFDIDSVGLTKLCARLNRGVDLADREIRYQTDIFIGVA
SNPTSNDLEAEFAHFGNKSQAGAHFTMTQPIYELDSLKRFLDECKPTVPILVGVLPLRNA
RHASFLHNEVPGMFIPQGIRDRMTKAGDDGPQEGVAIAQEFLAEAKKLCQGVYLMP
>A0A7Y5LQK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MKSAYFLDLLSERVLVADGAMGTRLYEYGIHFDHCFDELNISQPNLIRQIHADYINAGAD
IIETNTFGTNTIRLQQWGFSEKSREIAREGAFLAKNAVRDRNIERDVLVAGSIGPLGKPI
APIGRISSEEAAAAFREGIIGLLEGGVDLLLLETFMDQTEALVALQVARELDPNIAIIAM
MSFTDEGKTVFGNKPEEVVRVLSQHGADVVGANCSVGPQGLGDVLDRMLRVPDVPLCVMP
NAGMPTLVEGRYLYLSSPDYFGKQMEEFVERGVNIVGGCCGTNPSHIAALANRIRGKRPR
AHSPQQTNLERPTLEIIAPTESTEDDKPTELSDKLARGHFTVSVELDPPRGIDPKVLIKG
AALCKAAGIDAINIADSPLARARMSPLALAVLIRREVDIEVIIHMSCRDRNLLGLQSECM
GAHALGIRNILCVTGDPPQIGDYPDATGVFDVDSVGLTTLLKRLNDGVDLAGKKIDYHTQ
FTIGVAANPTAVDPQVENERFHRKIAAGCDFVMTQPIYDVDVLKQWVEETRPTVPVLVGI
LPLRNGRHAEFIHNEVPGMTVPASIRERMHNAGADGPAEGVRIAQEILLASKNWVQGAYL
MPPFNRFEMAIDVCRVLPGFDDVATREKP
>A0A6G7YRA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas piscis|TrEMBL
MSSVLPQTRAPLFAETHGDIDVSFEFFPPKTEKMEQTLWESIKTLEPLGPRFVSVTYGAG
GSTRERTHATVERIARDTSLTAAAHLTCVSATREEVDEVARHYWEAGVRHIVALRGDPPE
LGSKYEQHPGGYANAAELVAGLKKIAPFDISVAAYPECHPDSGDKAADLENLRRKVHAGA
DRAITQFFFSPDAFLRFRDDVAAAGIDVEIVPGILPVSNVAQTRKFAGACGAAIPKWMDN
LFEGLDELPEARKLIAATVAAEMCGQLYAGGIRHFHFYTLNRAELSYAICHLLGVRASKP
AIEEAA
>A0A7W3G7Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella sp. RHBSTW-00215|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRAIAQDYWDSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A2F0ARU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MMTFLDLAKNGGLLFDGAMGTMLYQRGIFLNRCFEAVNLEQPELVSRVHQEYLQAGAQVI
TANTFGSGRLKLEKQGLSDKFEDINRRGVELARAAVDGRAYVAGSVGPSGIVGLSGLAGE
EGLRAEESLREHIALLVDAGVDLLCLETFAVVSELEMAIRISKEYCDLPVVALCMFTEGG
STRRGLTPEAVGRRLIDAGADVIGANCGGGPDHLFGVTTRMVDLGHPVVAMANAGNPKTV
ENRTIYVANPEYFGVFARRLFKAGVKVVGGCCGTTPEHVRRMANSARMLRATNGVLDAEY
IDSATEYSGHSTPLADRSDLGACLDRNEFVTSVELNPPNGLDLSSRIEAARALKDFGITT
INIADGPRASLRMGNVAMAVEVAQKTSLSPLVHVCCRDRNYLGLQSHLLGMHVLGIRNIV
VITGDPPKMGPFPHATGVYDVNSIGLLNLIQGFNHGLDASGQTLPDRTSFVCATGAEPAA
HDYDRELRRLEMKISAGASVIMTQPVYDPAVIERFLNDIKEFNVPVMLGLCPLASYRNAV
FLNKNVPGMSVPDDVLARMKVAEDKGQGQAEGVAIARDALDASRTRIQGAYIMPPFGRYK
VAMAVLDGFLDP
>A0A6I1IB30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium violaceinigrum|TrEMBL
MANHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEEAAPHLSCVGGSRESIRAVLADFKAAGVNRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>K0YYB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Slackia piriformis YIT 12062|TrEMBL
MQISQAFQGESLPISFEIFPPKGDLPVETAHAMTEELAPLDPAFVSVTYSAGGSGNSART
IDVARMMKEDFALPIMAHLTCMGATKDDIDATLAAMREVGLENVLALRGDPVPGAATNDF
HFAKDLIPVVREAGFCVGAAAYPEGHIDCLDFKKSIEHLKEKQDAGAQFFVTQLFFDNDC
ALEFLEAARNAGITVPITFGIMPFLSKAQISRMVFMCGASLPSPIIKLLARYEEDPESLR
AAGIEYACDQMEGLAQAGVDGIHVYTMNQPSIARAAVARLRGAAS
>A0A1B6VLG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter cerinus|TrEMBL
MPAQTGPLPAISFEFFPAKSEKAAVTLLENAKTLAAFGPQFMSVTYGAGGSTRDRTLATL
KDMVRETGAPMAGHLTCVGASKEDVNAVAQAYWDAGVKHIVALRGDPPPSAGGVYEPHPE
GYAGAVDLVRGLKEIAPFEISVAAYPETHPAALSPQSDLEHLRAKIDAGADRALTQFFFE
ADTFLRFRDRAAAIGIERPIVPGILPVGSAAQAWKFADMCGANVPKWMRDLFEGLDETPQ
ARAFVAATIADRLCQRLKAGGVEQFHFYTLNHADTASALCRLLGRRPI
>A0A1F9DRA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_19FT_COMBO_46_9|TrEMBL
FTCIGNTKEDIISKMRHYRSIGIENILAMRGDLPKGWQGTQGDFSNADGLINFINKKFPE
FCIAAACYPEKHILAPSFSADIAHLRTKQDNGAEFLVSQLCHDVNAYTTFVDRIRKAGID
LPVVLGIMPVLDKDAIIRMTLSNGCSIPDELATIIGKYGDNPDDFKKAGIEYTINQIFRF
ISAGIVGLHIYTLNKYEDVETIITSSGIRKGV
>A0A0E2D1W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans str. UI 12758|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESA
>A0A0S8I486|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium SM23_61|TrEMBL
MTFQERLQENKFSITCEINPPKGTDAAETLEGAEALKGRVDALAVTDGKSSVMAMNPLVM
SHLLQRRGFETLLHLSCRDRNRLALQADLLGAAALGVGNLVVVTGDYASMGDHPQTKPVF
DLDAVQLLKVIQKMEKGQDLGGYPLKGRPKFFAGATVSPSPGREAALELQLIRMEKKMAA
GARFFLTQPVFDVPAFSRFMKQAASFGVPILASVLPLKSASMARFINKNLPGVSVPEAFI
EEIGAAPDRVKASLDLCARLVGELRGLCQGVHFIPAGWERKIPAILEAARL
>A0A1G8D3A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus triatomae|TrEMBL
MNFDAVRGRASDGWVTSTPSVIDRLRTRDSGRVPFSVEFSPPRDEAAEARLWRAVRVFER
LGPSFVSMTYGAGGSTRDRTVRVTGDLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWVKHPDGVEYAEDLVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVEQYLRLRDRVAAFDPIEGAKPIIPEIMPITSLRSV
RRMVELSGSSLPPDLERRLANAAGDGPEENRAAVREIGIDMATEMCERLVAEGAPGLHFI
TLNFARATAEVLERLGDKIGSAVPAGSVPEVPARAVS
>A0A7V5KUI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKPDFVDYIQEHVVLGDGALGSYLFERGVERGRNLDLLNLQAEETIFSAHEEYIRAGSQL
IETNTFGAGRFKLREAGAEDQVREINRAGARIAAKAAGHQVFVAGSIGPTGETFPLEEGE
VTEEEIRASFTEQVLGLAEGGADVLIIETFSQLQEILLAIEIARREAPQLPVIAQMVFPA
RSMTVHGEDALTCGRRMREAGAVVVGTNCGRGIDAMVTAVARMSPLAGEGTPLSAFPNAG
MPEMVGGRTIYPAQPGYMAARAREMIKSGVHLIGGCCGTTPAHIQEFRSALRIKPVRVRG
ERVVTVDRESDGDEKALKTGGFLESLAKKRLPIIVELDPPTHLDVDSVLHGAEELTRAGV
DAVSLGESPLAILRTGNLGMAARIRQRCGVQTIIHQTGRDLNGLGLQSRMMEAHLLGIEA
VLAVSGDSAAGTDQPGVTGVFDLRSEGLIRMLAGLNRGVNLAGRSIKKETNFSIGAAFSF
RPAKPGLQISRLEKKNALGARFAMTQPLFSREVVEQMMEAVNHINILIFPGIFPLISSRN
AEFLHNEVPGISVPADLRARLASYDQVADQRKAALEYTGRLIEDILPSIHGLYLISPLNK
WDIVLEFVRQVRGAA
>A0A7J5VR14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKSESNLERVLRAGEFAVTGELGPPKSGNPEVVREKARLLKGFVDAVNITDCQTAIVRMS
SIAAGLITQSEGVEPVIQMTCRDRNRIGMQSDILGASALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQMLGMVKAMRDEKRFQCGEEIKNSEPRLFLGAAANPFAYPFEYRAVRLGKK
VLAGADFIQTQIIYNVEKFTRFMEMVRDLGLDEKVFILAGVTPPKSLGMVRYMKSSVPGM
DVPDEIIRRMKDAKDKQEEGINICVEIIRQVKEIKGVAGVHVMAIEWESVVPEILKRAGL
LPRPAVFAEGEVQPVVAVEGSQESIQIATMASDALLAKARAEAEEIVATARREAEGVLEK
AGMAVSPASAVRGAVVEASLQGIAAPAGGENGIIDDAGENEMNEKERIMALEAVNQGLSA
LKKAYGLTDEQFAAITSFAGAHAILNREPPVAGAAAVPAVSAAPVAAVAAPAVKAAVDTA
AEDAAKAKAAAAEADAKIKAEAEAKALATAQKAATEKAAAEAKLKAEAQTAAAAQAKAEE
VAKAKAPAEAETKLKAAASVAAPPVAGDFAVAALSHGATSLAERSTKVDEKSYREKYTGV
IRETVLGNGDHTITVGGAASMPFHLFEGKHPHKSLIAMDVLDARPDDWPETLARHFTDVM
DNPVAWAQKCIKEYGAEAINISLVSTDPNGMNRSAADAAKIAAQIIEAVEVPIIVWGCGN
NEKDTETLRDLTSVIGNKKVCLAPLEDANYRAIGATAMAFQHAIVAASPIDVNLAKQMNI
LLQNLGVSLETVLMDPSVGALGYGIEYTYSVMERIRMAALIQQDEKLQVPIICNLGREVW
KAKETKLPSDAMIGDQEKRGIMMEALTASCMLLAGGEVLIMRHPKAVAMTKALINGLMD
>A0A853SEH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium lividum|TrEMBL
MGHLLMHPAQPRPAGNITHAYSLEVSAKDMPALSAAAPRIAPASTIAIPYLPREDNDARL
AAARTVRSLGFEPMLHLSARRIASLAEFESLIQRAVTEAGVERCFVIAGDPSTPMGPFSD
SASLIDTGVFERAGIKVIGVGGHPEGHPVMSTAEQWEVLERKCDSIGKRGMAPLIVTQFA
FDADIVLTWLKTLRERGIDHPVRVGVPGPASIAVLARYAAVCGVSACASMWSKYGVSIGK
LFGTAGPDLFVERLTAGLTEAHGVVSLHFFPFGGIAQSVKWIEQYRSRTGPGP
>A0A354EEP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MAAMKPPFLEYLREHVVLADGALGSFLYEKGVERGRNLDLLNLQSAELVFSVHEEYIRAG
SQLIETNTFGANLFKLREVGAEEQVREINRAGAAIAVKAAGHQVYVAGSLGPSGINFPLD
EEEFSAEDISQAFQEQTAGLVEGGVDLLIVETFTSLQEILLAIQAARVVAPTMPLVAQMV
FPARGTTVRGKDAFSCGRAMAEAGADVVGTNCGRGIDAMVTAVALMMPLAREGILLSAFP
NAGMPEMDGDRMIYPAQPAYMAARAGEMIKYGVHLIGGCCGTNPAHIQEFRSRLKIRPVR
IRGESQAEPQESVPRKEVEDRPGGFLSSLQPGRLPIIVELDPPTHLDVEPVLAGAGELAR
AGADAISLGENPLAILRTGNLGVATLMRRQAGIQTIIHQTGRDLNALGLQSRMMEAHLLG
IEAVLAVSGDSASATDQPGVSGVFDLRSYGLLRMLRNLNNGLNLAGRSIKQRTNFSVGAA
FSFRAESPGLQIQRLEKKAELGARFAMTQPLFTREAVEEMMAKTRHIDILIFPGIFPVIS
ARNAEFLHNEVPGITVPLELRRQLAAFEQVSDQRKAALDYTRQLVETIAPVVDGLYFISP
LNKWEIALEFVRQVRAGNWQGSGRADRLRTTHSTH
>A0A5B8J225|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus polymyxa|TrEMBL
MKPDLRTVLNREIIVGDGAMGTFLYQLGFPVNTSYEELNITSPDVISDVHGQYLNAGSRL
LETNTFSANDYKLARFGLESKVEEINRAGVRIAKAAAGPEHYVVGAVGSICGGKRLNISK
LELSRNYEQQIDALLSEGVDGILCETFYSLDEMRIALHSVRKYSDIPVICQFAVDQVGRT
QDGFLVAEAFSTLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECATSFADLGTRLIGGCCGTTPDHIAAISKALNNVQPPPLASLEALS
TESIHVVEQTANEGGRGNGRHASGPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHALK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYIMTQPVYDPELITAIAQETRHLEVPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGSEGRAMGVSIAKELLDTAMEHFNGIYLMTP
FMFYEMTAELTSYVWQKSGRALAPLFRL
>A0A7Y5HDJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Brocadiae bacterium|TrEMBL
MTIAHLFGTPRPVLSFEVFPPKRDGDVESLYRAFDELAPLRPDYISVTYGAGGSNVGLHH
EINARLVRLGITPLAHFTCVGQGREAIRTQLDRLRDAGVRNVLALRGDPPKGTGAFEPHP
DGFRHASELIAYIRERYAFCVGAACYPETHLEATSPADDLAHLVRKTRAGADFLVTQMFF
DNAAYFAFVRRCREAGITVPIQPGVMPVMTPKFFDREWGVAVPAELKRSLQEAAGADEAA
ASGLAFAIAQCRDLLAQGAPGLHLYIMNRVRPARAILKSLEGESGRGGESLPSK
>A0A6M7U0Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium loti|TrEMBL
MTARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A354ECH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MLSVLNFCELINNCSMATQNKFTRSLFNPEEFTTTFELVPGQGSGGRRIDRLLDFARQAQ
ADGRIKALSITDNPGGHPALAPHAIGSEVLRIGIQPLLHFSLKDKNRNQVESHLFLYHRQ
GFNNLLILGGDFPRPSYYGQARPVFDLDSVQTLRLMRDMEESTYRSDAPNRDQEFAPVSF
HRGCVVSPFKMTEAEQVWQYAKLLYKVRAGAHFIITQLGYDVCKFEELASFLREQEIFMP
VLANVFVPSLAVARYMSGGRVPGIVFPEKLLNAMEQEAQRGDREARLLRAAKLICVLRGL
GFAGVHLGGNGLSFANVRFILDTAEQLAPDWDKFRAEVHFSVKDTWYLYPPSRPGACGTI
RIALSPGRRRAAQLPPRFMHRLFFSPPNLSSRLFGGLCRLCAHSRAGTTLLCTLEKVLKG
ILFSCRMCGDCTLTESAYLCPQSGCPKNLLNGACGGSRYGACEVFPDRACFWVLVYNRAE
KTTTLRQLGNLPHMTPKDWSLARTSSWINFYTGRDHHRLTSLSTKA
>G7VVB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus terrae (strain HPL-003)|TrEMBL
MKPDLRTVLEREIIVGDGAMGTFLYQLGFPVNTSYEELNITSPDVISDVHRQYLQAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
VELARNYDQQIDALLSEGVDGILCETFYSLDEVRIALRGVRKYSNIPVICQFAVDQVGRT
QDGFSVEEAFTVLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAASFVELGTRIIGGCCGTTPEHIAAISKALNGLQPPPLAPREILT
DAPVIVAEPEQIAREGERGNGINASEPNIVELVKERHTVIVELDPPRDLDITRFMQGAQA
LKAAGADALTLADNSLAVTRMSNMALGHLVSLETGLRPLIHIACRDRNLIGTQSHMMGFD
ALGIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKANFVV
GAAFNPNVKHLGKAVQRLEKKIASGADYIMTQPVYDHELIIAMAEQTRHLEVPIFIGIMP
LASGRNAEYLHNEVPGIQLSDEVRARMSGLEGEEGRAMGVTIAKELLDTAMEHFNGIYLM
TPFMFYEMTAELTSYVWQKSGSVQAPLFRL
>A0A4P5VBI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp|TrEMBL
MMGRSDTGVLRLQQALEVGSFAITAEVMPPRGADVSRTLAHARLLKGLVHAVNVTDGSRA
VMRMSSLAVCKLLLEAGIEPVWQLACRDRNRIGLQAELLGAHALGIRNLLCLTGDPVRAG
DQPEVRPVNELESVRLLQQVSAFNQGLDPVAGLLPDGPTNLFAGAAADPQSPSWSGLKSR
ITRKREAGARFLQTQMVMDGDCLQRFVEEIAAPLGLPVLAGVFLLKSAKNAAFINRMVPG
ANIPQAVIDRLAAAADPADEGITIAAEQVARYAAVAQGVHLMAVKAEERIPLILERAGIS
SRC
>A0A3G2EHB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium agaricidamnosum|TrEMBL
MEKHNFSIEFFPPKTLEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVKRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGANAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>D7BAR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meiothermus silvanus (strain ATCC 700542 / DSM 9946 / VI-R2)|TrEMBL
MKIHTQFAPGKPLFSFEFFPPKTEEGEAQLFRTLHILKPLQPAFVSVTYGAGGSARGKTV
EWVERIKREVGLEVMAHLTCVGATREEIGEVLEQLRQVGAENLMAVRGDPPKGQREFRPV
EGGFRYASELVAFIRERYGDAFSIAGGAYPEGHPECTSLEADLHNLKHKVDAGLDFLVTQ
LFFNNALYLGFVERARRVGIEVPIVPGLMPITNLAQVRRFTEMCGASLPVPLLAQLEKFA
DDPQAVLEIGVEHTTRQALELLEVGAPGIHFYTLNKSPATRWVVENLRSRVRAL
>A0A1Y5R9R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius litorisediminis|TrEMBL
MIDSGAHGADLLAYSKPPEGHVSHSRLERVLRSGRFAVTAELNPPDSADAADVFEAAQPL
GEVADAINATDASGANCHMSSIGICALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAALG
VSNVLCLTGDGVGVGDQAGAKPVFDFDSLTLLRTIRTMRDKGVFLSGRKITRPPLLFLGA
AENPCIQPYEWRPDRLIKKIEAGAEFIQTNYIFDIPLFEKFMARVRDEGADKRVFIIAGV
GPLASAKAARWMRSNVPGIHIPDQVIARMERAANQSEEGKKICIELMQQLREIEGVAGVH
IMAYRREHLVSSIILESGVLSGRRRVKR
>A0A285BMF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TLI_55|TrEMBL
MAAAGLRALLESVRYEVLPAKATEDKVLTHVPRDVVVTVTASPVKGLEPTLGLAGRLAAH
GYRVVPHVPARLLRDDAHLKDVVDRLAEAGVADVFVPAGDADPPAGGYDGALPVLRRLSE
LGSPFARVGVTGYPESHPLIHDDVTVQAMWDKREHATYIVSNLCFDPRVLGDWLVRIRAR
NITLPVHVGVAGPVQRAKLLAMATKIGVGESTRFLTKHASWFVRFATPGGYAPERLLSRA
EAALTAPSAGVAGLHLFTFNQIAETEKWRRALLDRLGS
>A0A521A0M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKAGSNLERVLEAGHFAVTAECGPPRGADPDKVLQKADLVKGNVDACNVTDNQTSVVRMS
SVAGCMLVKESGTEPLLQMVVRDRNRIALQSDLLGASALGVRNLLCLSGDHQKFGDDPQA
KNVFDIDSIQLIHLVKTMRDEGVFPSGDKLEGAPKFYIGCAINPFADPFEIRVPRFKLKI
DAGADFVQTQCIYNMDKFKRFMDEARKDGLHEKTKILAGVTPLKSAGMAKFMNRMVAGIE
IPEEFIKRIADEPKEKQAAKGIEMCIEQIQEIKEMEGIAGVHVMAIEWEEKLNEIIGGAG
LLPRPMVEQ
>A0A0M4CEM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium deserti GIMN1.010|TrEMBL
MSSTNIPGSSQWAISDVLKRASPGRVPFSVEFMPPRDDAAEERLYRAAEVFHDLGASFVS
ITYGAGGSTRERTSRIARRLAQQPLTTLVHLTLIEHTREEMRGILQNYLENGVTNLLALR
GDPPGDPLGDWIGTEGGLNYTSELIDMINETPEFAAFDIGIASFPEGHFRAKSLEEDTKY
TIAKLRAGAEYSITQMFFDVDHFLRLRDRLIAADPIHGAKPIIPGIMPITSLQAAQRQMA
LSGSQLPAKLEADLIRAANGDEEANKDEIRKVGIEFSTQMAERLIAEGVSDLHFMTLNFT
RATQEVLYNLGMAPAWGAELGHDAVR
>X0NGX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. vasinfectum 25433|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A7K0K382|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobiluncus porci|TrEMBL
MTIKNLYLPTAITGVPAQKLRVSFELYPPRNPDPASQAWAGIDRLLDARPDYVSVTFGTS
GMTSTSSQSVLVHAMKRSGRPALAHLTCVGRNQSQLAGLVRDMMDLGVRDFLALRGDPPK
GVAHWEPETGEFSRAFQLVGLIREVAADYLGDPQAVSISVAAYPAGTVQTRTDAVAALVE
KQAAGADFAITQVFYEAKDYADLVHSASYQGVTMPIVPGIIPFTDVSRLNRLEGLTGVPV
PKRLREIGEIPDPAERILESLGATLDFVNDLIAVGAPGIHFYTFNRPRPVLDLVEHLRSR
GFSHVDKADSSDLLGLMSAAMHRFSP
>A0A238Y8H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halorubrum vacuolatum|TrEMBL
MTPKFRSSTTKEGVETLLESPRYELMPFDSFGEQITHLPNGAAIAITTSPQLGLEATIEW
AETASEDGYEIIPHIAARYVEDRAELESIVERLETAGISDIFVPGGDREEPKGEFESAYE
LLVALNEIGHEFEEIGITGYPEGHAFIDDDTLAASMEKKSPYATYIVTQLCYDHEAVLDW
IEKIRSRGVELPVEVGIPGVMKYQRLLQISKKVGVGDSVRFLQKTTGVLGFIRQFVGSRG
KYTPDDLVDGLGPYANDPTYDISGIHLYTFNQVPDLESWRNDKLRE
>A0A8H9LIT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces gougerotii|TrEMBL
MALGTASTRTDHAPTVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSEDWDTDIRYFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LQDDKG
>A0A2K6RU66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhinopithecus roxellana|TrEMBL
MDHRKARVLPAGHYCPSLGVWASQAGSMRFSVPPSISRNLAMVNEARGNGSPNPCLEGSA
SSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSIMIASTAVNYCGLETILHMTCCCQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTNMGITCPIIPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDTLELLNRPTQNERETETP
>A0A1C5WEF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Roseburia sp|TrEMBL
MNIKEYIKEQRLITDGAMGTYYEEKYSEDTVIAEKENLKNPEQIKEIHLEYLRAGARLIR
TNTFAANTMFLADMQEVKETVRAGYEIAKEAVTAFQAENGKEIPVFIGADLGPIYDLDHQ
DYDNVLQEYKEICDTFLSCGADCFVFETQSDFTYIEPVTAYIKEKSDAFILVQFAFDKSG
YTRSGLSMQRVAVEASEMENVDAYGFNCELDSTHMYQFMKNLKFSSDKFVSALPNAGYPY
TLRGKTIYSNNASYYAEKMKDIAALGTDILGGCCGTTPEYIALLSGELQDVPKAAKKIEN
VVTQEVTRTPSIFEEKLSHGEKAYIVELDPPFSEDASKVMKGAEDLRKCNVDLITLSDSP
MARARMDAGQLAVKIQQKTGVAVMPHISCRDRNVIALRAGLLGMHMNDVRHFLIVTGDPV
SRADRERVTSVFDFNSIKLMQYVKEMNLEVFAQEPVYYGGALNYHGANPDAIIERMKRKA
EAGCGYFLTQPVYTEEDVERLTYIKEHIDTKIMCGIMPLVSYKNAMFVKNEMPGIHVSDE
IVNRYREDMTREEAEEVAIELSVEIAAKLYDIADGFYFMTPFNRTGLIARIIEAIRQEEE
RR
>A3NEQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei (strain 668)|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>B3DS64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum (strain DJO10A)|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A3D8UPF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HD9-500m-PIT-SAG08|TrEMBL
MKFSLEIGPQTDLNTVPQVKDVYITMLPGGDYRETAQQAVELVKKGFNPVPHFPARSMLD
EKQLKDYVSRCKDGGVKQVLVIGGGREPMGKFDSSFQLLETGYFEKMTIGIAGHPEGSPD
ISDSDLEKAMIDKKPYADYIVTQWLLDPQPIIDFVSKQSVPVHVGITGPLKISSLIKFAN
IVGAKNSINFLKSNFTKALDLLKPKDPNDLIGKVKSHTDFFHIYTFGGLKETNKWLKENG
YV
>A0A346S041|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. Arc7-DN-1|TrEMBL
MQSQKQFRRRFSFEFFPPKTDQGKEKLQNVRNQLAGVNPDFFSVTFGAGGSTRDRTIETV
LNLHRQGISTAPHLSCVGGTRQEIGELLDLYKEHGINRIVALRGDLPSGMGAAGELRHAN
ELVAFIREHSGDTFNLEVAAYPEFHPQARNAEEDLQNFARKVKAGANSAITQYFFNADSY
FYFIDRLEQMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEVPRWIRKQLEAYGDDSDSIRK
FGEEVVTGMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISDREKIAF
>A0A2G9FDV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. animalis|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSLEKPDYISVTYGAGGNTKGKTV
EIADRIKRQNGVESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPIDRELEKGD
FNYARELIEYIHKKKGDKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRHE
>A0A4R7SI84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. KS 21|TrEMBL
MALGTASTRTDRARTVRDLLASGSPSYSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSV
TYGAGGSTRGGTVKATQQIAADTTLTPVAHLTAVDHSIAELRNVIGQFADAGIRNMLAVR
GDPPGDPMGPWLAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSAGKAGCETPIIPEVMPVVGIKQLDRLPQLSNAVF
PAAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQRA
>A0A4R5LFZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia guartelaensis|TrEMBL
MKPIELSFEFFPPKTPDGVEKLRATRAQLATLKPKFVSVTFGAGGSTQQGTLDTVVDIAK
EGVDAAPHLSCIGSSKEDLRAILGEYRSHGIRHIVALRGDLPSGMGSVGELRYASELVAF
IREETGDAFHIEVAAYPEYHPQARSPRHDLEAFAQKVKAGANSAITQYFFNADAYFRFVD
DAKKLGVDIPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTDLCRRLVEAGVPGIHFYTLNAAPATKAICERLGY
>A0A1V5W0H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin217|TrEMBL
MNVAHTIQTTTKTLFSFEILPPLKGKGIETIYNTIDPLMEYKPQFINITSHREVYDANNN
RVRRRPGTVAIAGAISHKYNIPVVPHILCGGFNRKETEYVLLDLHFLGINNVLALRGDAL
RSDEPYTPEPEGNRYAQDLLRQIADMNKGKFIGDTDYNTSSPTHFSCGVAGYPEKHYAAP
DLDTDILHLKEKQDAGAQYIITQMFFDNAHYFNFVAKCRAVGITIPIVPGIKPIGLKNQV
DVLPKLFHIELPQDLDTALRACSDDEQAKQIGTQWAIMQAKELIAHNVPLLHLFTYSSAK
QSVEIAKAVF
>A0A7V8ATT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSLHKAFEKGKFVVTSEIGPPKGTDTDDIRRLVDLYRGAVDAINATDNQSAVMRMSSLAV
CKIILERGAEPILQMTCRDRNRIGLQSDLLGAHALGIRNVVVMTGDHVLAGDHRQAKPVY
DVESVQLLNIINSLNNGADMAGNALKGNTCFFAGAVVTPEANPLEPQLMKFAKKIQAGAK
YFQTQAIYDITMFKVFMGHARRHQAKVLAGIVVLKNERMAKYLNDNVAGIRVPQDLIAEL
AAAPNREEKQKAGIRIAARHIRRLREERICDGVHIMAIGMEGSVPAIMQQAGLLE
>A0A7W5MJL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. BK345|TrEMBL
MTFSVNQLEEARRALDAPLYADVGGDVDVSFEFSPPKSEKSEETLWQSIETLCPLGPRFL
SVTYGAGGSTRDRTHATVARIARETAVPAAAHLTCVEATREQIDAVAQEYWAAGVRHIVA
LRGDPPAGAADYAPHPGGYENAAALVAGLRRLHPFEISVAAYPECHPSSADLAGDLDNLK
RKLDAGANRAITQFFFEAETFFRYRDAAAAAGIQAEIVPGIMPIGSFAGVQRMAAMCRTD
VPGWLARLFEGLDDLPAARQLVAATVAAELCRKLYAGGVKQLHFYTMNKAELSYAICHLL
GVRATPRQAAAAA
>A0A198G0V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus myxofaciens ATCC 19692|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTEEMESTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDACRDELKHIAQDYWDSGIRHIVALRGD
LPDNSTQPEMYATDLVHLLKDIGDFDISVAAYPEVHPQAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFNQLKRFAGLTNVKIPGWMNKMFD
GLDNDPETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELAYAICHTLGVRPAVN
>A0A6J4QJX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Rubrobacteraceae bacterium|TrEMBL
MLDLREKFGERLLVGDGAVGTLLGDRGITRPHTRANLTHPQIVRDLHEEYLRAGSSVIET
NTFAANRLKLAAHGLEEKVREINLEGARLALEATKAVTGSNGGQALVMGSIGPLGKPLAP
IGVIQTGEAKDIFAEQAEALLEGGAEALILETFTDLEELKIAYEAVASLGAPVLAYKTFI
EDGEQLAEGLPARVAREISSWGSDGSGPVVIGTNCTVGPQRMLEIVEQMAIEAGPVAAYP
NPGLPQFIHGTIRYNQDVNHFAEYGVKLAHAGARLIGGCCGTTPAHVKALAEALRDFEPN
GGVSRRASTATVERVEKRATEPVTRFAEKIREGFAVTVEVDLPRGHDISEVVEAARDLKE
RGVHAIDISDGARARLRMDPIAVAKTVQDEVGIEVVAHLSCRDRNIIGLQSDLLGAAALG
VKNILAITGDPPQIGDFPEATGVFDTGAVGLVHILGRFNQGEDLAGNPIGEPPGFLIGAA
FNPTAEDLDAEVDKLKQKIEAGAHAYWTQPVFEIGSLEIALEKLEAEDLDVALLLGLMPL
RSGRQAEFLHHEVPGIDIPKHVREKLTSLDKDDAPKYGVEVAQKLLVEAKPLVNGVYLMP
PASMPHLAGDVMEAVSS
>A0A1R0WD97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL H7-0326|TrEMBL
MADLREVLKNEVIIGDGAMGTQLYQMGVPVGVSYEELNLTSPEMVKDVHRRYIEAGARLI
ETNTFSANYVNLSKYGLEDQVEAINRAGVRVAREAMGNKGFVVGAVGAIRAGKRADISAA
KLNLYFEQQISALVGEGIDGVLLETFYDVEELVIAVRQVKKLTDLPIICQFAIDDVGRTF
DGFTMPEAFSILHKEGADVIGFNCRTGPNGIMRAMESVQNLGIPMSVFPNAGLAEYVDGE
YRYGASAEYFGQSAVRFADLNARIIGGCCGTTPEHIKAMVSALDTYEAAPLTVVDDELLP
LPDSVSETLADGSAAGTIRTEPTIVDLVKERHTVIVELDPPRDLDIQKFLTGAKSLKKAG
VDALTLADNSLAVTRMSNMALGYLAKEQTGLRPLIHIACRDRNMIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPDSSSVYDLTSFEIIRMIKQLNSGIAFSGKPLKQKADFIVGAAFN
PNVKYLEKAVQRLEKKIAAGADYIMTQPIYDPKLFVQLKEATSHLDIPIFVGIMPLASGR
NAEYLHNEVPGIQLSDAVRERMAGLEGEEGRKVGTAIAKELLDVAMEHFNGIYIMTPFMF
YGMSEELTHYVWEKSGRVIKT
>A0A7V9JM98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MTAVIDRLGGDRPVFSVEFSPPRDDAGERQLWQAVRDFEPLDPAFASVTYGAGGSNRDRT
LRITKRIVQETTVVAMAHLTAVNHSVAELRQVIGNYAQAGIRNVLALRGDPPGDPLGEWV
AHPQGVHYAADLVRLARSLDDFCVGVAAFPERHPRSLDAESDVRYLVAKLRAGAQFAITQ
MFFRPEDYLRLRDRVAAAGADMATVPILAGVMPITTLRGVQKMAELSGCTIPAAVRDRLV
AVGDDAAAVRQVGVDVASELCERLLAEGVPGLHFYTLNRSGSTRAVLARLEMAPTVATR
>A0A5S9N3F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|BD1-7 clade bacterium|TrEMBL
MSHSDKRFSFEFFPPKTEAGHAKLEKTWADLNALNPAFFSCTYGAGGSTRDNTFGVIKQM
REQGISIAPHLSFGGDDETAMTELLDRYKALGVDRIVALRGDIPSGMGAAKIVYANELVE
FIRNHSGDHFELEVAAYPEIHPESKSYDADIHYFKQKLDAGANAAITQYFFNPDAYFQFI
DACTKAGINKPIYPGIMPITNFTNLARFSAHCGAEIPRWIKYKIENCGDDQDAVIETGKD
IVIRLSEQLLAGGAPGIHFYTMNQVEPSKAIYQAIV
>A0A6J4QWZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Rubrobacteraceae bacterium|TrEMBL
MQSQRNHSKVFSVELFPPKTPAGEENLTVALGPLAMLEPAFFSVTFGAGGTTRSGTIETV
VRTMNETGIEVAPHLSCIEGTRESIGGFLERYKEAGVRRIVALRGDLPGDMESPGVFSCA
TELVEFIREQTGDYFHIEVGCYPEFHPEAESAFADLAYFREKVEAGADSAMTQFFYNADA
YFNFVDQVERIGVDIPIIPGIMPIWDYPKVASFSAGCGAEIPLWLKKQMEAYGDDASSQR
QLGIEFVTDLCQRLLDAGAPGLHFYALNRAEPTSTIWNGLGLPVADASLLPRRRGE
>A0A7X8JR46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epulopiscium sp|TrEMBL
MKLSQIYSSDTRRISFEVFPPKPDIPIDTVFDTISGLKKLNPSYISVTYGAGGSSRGRTV
EIASKIKNEYGLEAMAHLTCAGHTKADIDYILEDLKQKGIENILALRGDPPINQPDFDYN
KNDFRYAVELIEYIKSKGDFSIAAAAYPEGHKDSKSITKDWCYLKEKVDAGVDVLITQLF
FDNRIFYHFMEDITKLGIHCPVIPGIMPIFNSKQIKRIISLCGSSMPGELLIMLDKYGDS
QEDLRKAGIDYAIRQIQDLLDHGVLGIHLEPMNRPALAEEIIKGLNYKFN
>A0A533YHZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MGNSPRRLKEILDRDGFAVTVEYNPPKGTNASALLDNAKSLVGRVHGVNVTDNTAAVMRA
SSLSICRLLYEMGHDPVMQITCRDRNRLAIQSDLLGAHLLGIRNILCLTGDYPTVGDHKD
AKPVYDLDSVQIMQLVQGLNNGRDLAGNKLDGSTDFLIAAAVTPEADPLGPMLVKFEAKV
NAGAQFFQTQAIYHPERFGVFMQAVRKFKVKVLAGILLLRSAKMAEFMNANIPGISVPDE
MIAELRAAGDKHALDAGVAIAVRSIKAVRPHCDGVHIMAIRAVDRLSEILTKAELG
>A0A428FYM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. dentisani|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKHIHQATHALFNHQSLG
>A0A172YAI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halotalea alkalilenta|TrEMBL
MSRTFEVSFEFFPPRTDAGREKLTATRDALMTKNPEFCSVTFGAGGSTRDRTLETVLELR
DGGVDAVPHLSCISSDKQELRELLARYRELGIRRIVALRGDIPSGQGGGGELRYASELIE
LIRAEHGDHFELLAAAYPEMHPQARDFESDLRFFAAKMKAGASRAITQYFFDAEAYFHFV
ERVRALGVEAPIIPGIMPVTQFDSLVRFSDVCGAGIPRWIRKQLEAYGDDQESMRAFGHE
MVSRLCERLIEGGAPGLHFYTLNQASPSLRILDSLGR
>A0A2M7HQC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. CG12_big_fil_rev_8_21_14_0_65_47_15|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPSWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A328FA68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacter hydrogenophilus|TrEMBL
MKTESRLEKVLASGQLAVTSEVGPPRGCNIDIVKEKANMIKDYVDGINITDNQTAMVRMS
SIAGGVVIKQMGLDPIIQMVSRDRNRLAMQADILGAYALGCNTMLCLSGDHPKFGDHPMA
KPVYDIDSINMIKMVKDMRDEGKFQGGADITEPPKMFIGAAANPFADPFELRVMRLAKKV
AAGVDFIQTQCIFNTAKFEEWMKQVVDRGLDEKVAILAGITPMKSLGMAKYMKSKVPGMD
IPDEVIDRLAGVDKEKQAEEGIKMAIEQMQRLKECKGVKGFHIMAIEWEQKVPELVKAAG
LYPRPEV
>A1HTM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosinus carboxydivorans Nor1|TrEMBL
MLIHQLFAQKRPVVSFEIFPPKPDSPLESIFDCIEELQALKPDFISVTYGAAGSTRGRTL
EVARHIQHDHGIPALGHLTCVGATAETIQAILHEFAAHGIENILALRGDPPKNAPFPPTP
YRAKDLIRLIRQQRRSCSVAAAAYPEGHLESPSREDDLRFLKEKVDTGVDFLITQIFFDN
AILYRFLEDARALGIDVPVMAGIMPVFSRPQVERICSLCGATLPPALRKLMEKYGHDKEA
MEQAGLEYASRQIADLLAHDIDGVHLYTMNRPHLARTLVRNTSLR
>A0A1B2HBG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentzea guizhouensis|TrEMBL
MTSVVERLQGQSPKFSVEFLPPRNADDERILWTAVRELEALDPAFVSITYGAGGSSRDRT
IRATARVAQETTLLPVAHLTAVDHSVAELRNVIGWYAAVGVRNVLALRGDPPGDPMGEWV
AHPQGLTYAEELVRLVRELGDFCVGVAAFPYGHPRSGDLATDVKFLVRKLQAGADYAVAQ
LFHEPEPFLRMRDSVAATGCTATLLPGIMPMLSSRALTKIVELSGADLPVELARRLDRYA
DDPAGFRATGIDIATEMCQRLLDEGVPALHFYTMNRAKATREVLGRLGLVTRA
>A0A318A003|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 11986-1-5|TrEMBL
MGYTHASHIDALNQSIAEVSDINVSFEFFPPSTPQMEETLWSSVHRLKDLKPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDASREALITIADDYWHNGIASIVALRGDI
PPGGGKPEMYAADLVALLKSCHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDIESYLRFRDRCVAAGIDVEIIPGILPVSNFKQAARFAAQNHVKVPQWMAKQFAG
LDDDPITRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPMTTA
>A0A3M5N461|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas azotoformans|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2W6DHM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MARTVRDCLATGRPTISFEFMPPKTPEDERRIWKTIRELESLQPSFVSVTYGAGGSTRDN
TISVTERIAADTTLLPVAHLTAVNHSIAELRGIVGRFADAGIVNMLALRGDPPGTNVNAE
WVPHPGGVAYASDLVTLLATHGDFCIGVAAFPYKHPRSPSIEADTEMLVAKLRAGADYAI
TQMFFDGDDYLRLRDRVAAAGCDVPIIPGLMAVTTIGTIERSEQLSGAPFPPALARKFEA
VAAEPKAVRELGIAEATALAQRLLDEGAPGLHFITMNYSKATREVMSQVSLPAGV
>A0A1A0JV27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. EPI-003-04-2554_SCH2473622|TrEMBL
MAPRVSASAPLDDSSDNPDNPDNAENTEPRTRSERTALSFEVIPPRHDADEKKISHLLET
LQSYRPDYISVTSSCRSGWLDGTAKFISRIDRETNMRTLAHLACTAGTKQEMVAWINRLI
DSGVRGLLALRGDLPEGEVKLPADHLQYADELVRLIREVEGQQAARFAAGRLAVAVASYP
NGHYQARTDDENFDVLLSKQRNGADLAISQLFFEAEDFLKFRRRAELAGIRIPQIPGIMP
ITSVRRLRRMAEFSSLPVPEHLVRRLESARDERAEGIAITAELVQAMVDNDVGSLHIYTH
NNAEVTQELLDAVGIRPPTAPSPTAPG
>A0A522UNB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MKIVDVYGKGKFGLSFEIFPPKTEAGESLLFAALEALMAYRPSFVSCTYGA
>A0A1V5CGU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdaceae bacterium PtaU1.Bin034|TrEMBL
MNNTPIGPAILAIGAVVNPNFEPLDLQLMKMEKKIEAGAQFFQTQAVYDSARFESFIKQA
GRFGVPVQYGVVVIKSPEMARFMNNHVSGISVPDAFITEIGSVPKENRKEKAIEMTARLV
NEIVPMVQGIHFMPLGWSDVVPKVLEKTPLWTAN
>A0A423PX89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinisphaera halophila YIM 95161|TrEMBL
MTNASQSSYSIEFFPPKGPKGEARLDEARARLAELGPAFFSVTFGAGGTTRSGTLKTVKR
CMETTGIPAAPHLSCVEGTRESIGEFLDNYKAAGVDRIVALRGDLPEGMDRPAGEFAYAN
ELVEFIRERHGDDFHIEVGCYPEYHPQAPSPAADVDNFVRKVKAGADSAMTQYFYNADAY
FNFCDEAAAKGVDIPIVPGIMPITNFEQVSRFSAMCGADIPRWIRQKMESYGDDLESVQA
FGQDLVARLCERLLAGGAPGLHFYSLNKADPTCWLWRELGLPTQDTASAANG
>A0A5B0TRV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. FUC4|TrEMBL
MALSLKEKIEDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQARPFAFKQTVDPREYSHLLRNLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDL
QNVVLVGSPSSIGDIKLSLPDAYKALAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGITPQRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKLIA
>A0A8H4U6B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium zealandicum|TrEMBL
MDRITDRIAALPDDATYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFINVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRREE
YRDPDDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFVMTQLFFDFKAYEHFENTLRDHPSGVFKTIPIIPGLMPIQSFQMIKRT
TKLSHAQIPDDILARLQCVKGDDERVKMVGVDIVSELVEKVKEVKSKTPGPKGFHFYTLN
LEKAVSFILERTNLIPEPPQDEEAVVADDPIPIPALHINGSSNMRSGSNSRASRVSRRHS
SVGSDPHNRVIVGDRPATHPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDD
FPNGRFGDARSPAYGEIDGYGVSLHMSITQAVKYWGNPKTRQDINDLFVKHIQGELPAIP
WSEEELLAESSTIQPHLLQLNKKGWWTVASQPAVNGLRSSDATFGWGPANGFVFQKSFVE
FFIPEGEWYTLKEKLSSSELCDSVCYYASNARGDFVSSDTSGHVDGAAEAGPGTNAVTWG
VFPGKEITTPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSDSEKLLNGIKDGYWLVNLIH
HDFVEKDALWNVLSS
>A0A7W6UV80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium cellulosilyticum|TrEMBL
MMNETTTRPRFDISFEFFPPKSEEMEAQLFETVDRLALFQPEFVTVTYGAGGSTKEPTLS
AVTGIIDKTNLATAAHLTCVDASKDEVRSVVEEYRAAGVRRIVALRGDPTAGIGTTYLPH
ADGFQRTADLVQALAEYGDFDISVSAYPEKHPESRNMAADISVLKQKADAGAHRALTQFF
FDNEVFFRYMDEVAAAGVTIPVIPGIMPIQNLTQLKRFSKRCGATIPGFLDERFEGLDDN
PDDRAKVAAEVAAEQIEELGRNGFNHIHLYTMNRSPLVSAVLDNIGHKPGMRKAAA
>A0A7S0DVH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hanusia phi|TrEMBL
PAASVSISMTSPSLRTLSFARRCPPSSWPGGAASGDGRRPSRRLLSRGRDVLGGYSIETT
AKLRFSQDFFSSRLPRGTSVYVAAINGTCVEDVFRLCKQLREQGMCPVPHLAARSLRDLD
ELRGWLELARENDVEECLLIAGDNPKANGNLESSMHVLESGLVEGSSIKKINIAGHPEGS
LKIRDPLQHLQAKTRWAERHGIAMDIVTQICFNADMIFDFCMQVRSLGINNTIRVGMTGP
ISLSKLVKYAAVCGVGPSIQLLSSKPDLAFNLSQNDMSPLLHEFLRKIDDVSNLHG
>A0A1I2LPX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster clostridioformis|TrEMBL
MKIREILAEGKPTLSFEVFPPKTEDAYDSVEKAAAKIAKLKPSFMSVTYGAGGGTNDYTV
GIASAIKEEYAVTPLAHLTCVSSTREKVHHVLGELKERGIENVLALRGDIPQDGSTPKEY
HYASELIREIKKAGDFCIGAACYPEGHVESANKSVDMDYLKQKVEAGCDFVTTQMFFDNS
ILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTCLPSRFMSIVDRFGDNPAAM
KQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A7Y6T2A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium septentrionale|TrEMBL
MTETISSVPNGQRAPKTPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTITRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAAIKRRHADIEISVSAYPEKHPEAADFDADIDTLKAKVDAGA
ARAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A151RV29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cajanus cajan|TrEMBL
MERMVAHNPSFCDITWGAGGSTADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALH
TIKSNGLQNVLALRGDPPHGQDKFVQVEGGFACARDLVKHIRAKYGDYFGITVAGYPEAH
PDVIESNGLASPEGYQNDLAYLKSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPI
VPGIMPINNYKGFLRMTGFCKTKIPAEIMAALEPIKDNEEAVKSYGVHLGTEMCKKILAH
GIKTVHLYTLNMEKSALAILMNLGLIEETKISRALPWRRPANVFRVKEDVRPIFWANRPK
SYISRTIGWDQYPHGRWGYSCNPSYGALTDYQFMRPRSRDKKLIEEWAVPLKSVEDIYER
FRLYCLGKLRSNPWSELDGLQPETKIINELLEKINMKGFLTINSQPAVNGEKSDSHTVGW
GGPGGYVYQKAYVEFFCSKEKLDALVDKCKDRTSLTYMAVNKEGSWKSNAGQADVNAVTW
GVFPAKEIIQPTIVDPVSFNVWKDEAFEIWSRGWACLYPEGDASRKLVEEVGGSYFLVSL
VDNDYINGDLFAVFADF
>A0A094RXV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|actinobacterium acIB-AMD-7|TrEMBL
MSNDQRATSFSLEFFPPKDLAGEERLWQVLAQLQPLKPDFVSVTYGAGGSTRDRTIRVTT
EITDRTQIPTVAHLTCVGSTKSELVEVLNQYKTSGIKSILALRGDPQGGPTSQWQSIPTG
LDHADELVELAMQIGGFNIGVAAFPDGHPASNFDLEKDIDVLLRKEQLGASFATTQFFFE
FEKWQGIVDRLAKRGSNLPIIAGLLPITNLKQLNRMVELSGVKIPNHISKRFESAGDDPN
EIKKIGIDIATELGSKLLAAKVPGLHFYTMNTAESTIVIAKNLGLVK
>A0A1E4RE71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphopichia burtonii NRRL Y-1933|TrEMBL
MPSVKEKILSLKSNERFISFEFFPPKTDAGFRNLLARLSRMLALNPLFITVTWGAGGSTS
EKSLDLAATCQKELGLTTVLHLTCTNTNKEIIDDALSKAKSNGIRNILALRGDPPRTEEY
WTPNCDFNNAVDLVRYIKQQYGDYFCIGVAGYPEGHVDGSDNSQQSIEKDIPYLIEKIEA
GADFIITQLFFDVDKFLNYEKVLRSYPQLSNIILIPGLMPITTYKVFTRSTKLSHASVPD
DIATKLHDASVDDDKVKSLGIDIIDDIITNINNHTDNRIRGYHFYCLNLEKAVASIINKS
NVLLPIMDLHESVDNNDDAIASDSDDDLDANQVRMNRRKSSIVNENEPSTSKQDVLNGQK
SLIGKALLDDKKTLVDISIGKGALGKDATWDEFPNGRFGDSNSPAYGEIDGYGPTLKLHS
TKEIENTWGSPESTKDIIRVFIDYLSNKIDLLPWVDTELSPETALIQEELFELNNKGWFS
LASQPAVDGCKSSDKIFGWGPSNGVIYQKPFVELFVPKKDWNDIIYPRMKSWFDSKVVTY
YLGDCQNKITSNLSIGPNSHNSKSAITWGVFPLKEVLQPTIIDYESFKAWNEEAFLLWLE
WARCYKKTTKSFEILNNVYNDYYLVSLIHHDFKNESGLWDALLGNE
>A0A525CCZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MAKASISVEVFPPKTPQGTEKLLANLQTLAESRYISVTCGAGGSGQGYTTELVSTLSNQL
TVPIVPHITAAAYLTSEINAVLDYYYSIGIRTVLALGGDRPAGQGESIRTIFAVELVKHI
QQWNKTNDGRQKFSVGAAGYPEGHFATPNRSLELNYLKQKVDAGGDYLCTQLCFDNHDLL
DFRDRCAAAGINVPITVGIMPIQSQANYERIPQLALGTRYPAGLMRQISSCRNDKEIAAC
GMNWAIKQARQLISEGLTDIHLYSLNNADTSQQFFQALG
>A0A0F2TK18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rubellomurinus (strain ATCC 31215)|TrEMBL
MALGIASTRTDRALTVRELLAAGKRSFSFEFMPPRTEVGEQKLWDAIRRLEPLDPNFVCM
TYGAGGSSRERTVNMVGRIATETTLTPVAHLTAVDHSIAELRNIIGQYADQGVRNVLAVR
GDPPGDPMGEWVRHPEGVTYAYELVELIKGIGDFCVGVAASPNMHPRSTDWDEDIRHFVG
KIRAGADYAITQMFFEVDDYLRLRDRVAAAGCEAPIIPEIMPVTNAKQLERFPQLSGSAF
PAELEARLRAAIDDPAALRAVGMEHATAMAERLLAEGAPGLHFITLNHSTATLEIYQNLG
LHVR
>L1MFP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium durum F0235|TrEMBL
MPECRHFDIGIASFPEGHHRARTLEDDTYYTLAKLRAGAQYSITQMFFDVDHYLRLRDRL
AAADPEHGTKTVIPGLMPITSLRSVRRQVELSGAALPSALEERLERAAAGDEEKNRDEIR
KVGIEVTTAMAERLIAEGAPDLHFMTLNFARATQEVLHNLGMAPAWGTDAGQDAIR
>A0A2A5XWK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|alpha proteobacterium MED-G10|TrEMBL
MTLKKKKITVSFEFFPPKNQESIDSLWTNIRRLEPLNPSFISVTYGAGGSTRENTHSLVK
EIKNKTSLEPAAHLTCFGTSLNEIEKIADDYWSAGVKHLVALRGDVPKQQNTKKNDFKFA
TDLIKFLKSKYEFDITVSAYPEMHPDSKTKEQEYDVLKKKIDLGATKAITQFFFNVESYF
EFLDGAIKRGINIPIIPGILPVTNCKRTIEFANKMNCKMPNNLAEMFKGLDKDVETRKLV
AVTIVYDQCKKLIEGGINDFHFYTLNRADLSFAICHILGIRTLD
>V9WI23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter gallaeciensis DSM 26640|TrEMBL
MALLNFKKRDAGAVQPSSPEVEAFLENYSIEVMPRTAAKVENFRDLLPAGTRVYIAHIEG
TPIEEMVETAKRINAEGFPVMPHFPARIIQDEATLADWIARYQGEADVKQALLLAGGVAK
PHGAFDSSMQLLETGLFDKAGFNNLHVAGHPEGNKDIDPDGSMKNVSDALLWKQKFSERT
DANMALATQFAFEAKPIIEWAEGIKAAGVDLPIHIGIAGPAKLQTLIKFAIACGVGPSLK
VLQKRAMDVSKLLLPYEPTDVIAELAAHKAANPDFNITNVHFFPLGGIKTNATWAINNGG
AAAQPVNSQG
>A0A444WC95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium beibuense|TrEMBL
MKVTEHIENANGKALFSFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYTFKE
LPSGLLEKKVVKKRPGTVGICSAIQNKYGVDAIPHILCGGFTKEDTENFLIDLDFLGIEN
VVALRGDAVKSEIYFKPEKEGNVYASELVTQIVNLNKGIYLDDDLLNTSATDFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGASYIVTQMFFDNKKFFDFVGKCRKEGITVPIIPGLK
PLSTKKQLNQIPHRFKVDLPDELIMEIVKAKDNDAVRQIGIEWCIAQSKELVAAGIPVLH
YYSMGKSDNIKAIGKEVF
>A0A137NYW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Conidiobolus coronatus (strain ATCC 28846 / CBS 209.66 / NRRL 28638)|TrEMBL
MRISEKLNQKIKENKAYWSFEYFPPKTAQGVINLYDRMDRMYRLGPEYIDVTWGAGGTTS
DLTVEICTTAQQVHGLETSMHLTCTNMPKEKIDIALKQAKQAGIQNILALRGDPPRGQEN
WEKCENGFSYAVDLVKYIKEQYGDYFCISVAGYPEGHIDSGDDKEIDIQYLKEKVDAGAE
YIVTQLFYDVPLFLSWVQKCRQAGINVPIVPGIMPIQSYNGFKRMTTLSKTLVPQFIQNS
LDPIKDDDQAVKDYGVQLAIDMCKQILNAGITGFHFYTLNLEKSARLILEGLQFVNPAEL
YRPLPWNPSLAKNRENESVRPIFWKNRTQSYISRTEQWDDFPNGRWGDSRSPAYGELDGY
GISLKFNKQQALDIWDHPTTVEQLSELFAKYCQGKVSALPWCDQSLDNETRTIENELVQT
NHLGFLTINSQPSVNGAKSSDRVFGWGPKNGYVYQKAYIEFFCSPEKLSTLIEEINKNPQ
VTYYAVNKRGDLKTNNQIEGPIAVTWGVFPGREIAQPTIVEASSFMAWKDEAFELWSQWG
KLYDSGSDSEKLFANIRDNWFLVNVVDNDFTSSNKIFEIFGITPSYTENGSAAQRLTPPP
KF
>A0A848SM97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium|TrEMBL
MNRPTLDQLQEARRALDDPLFADLAGDAKVSFEFFPPKTEKMEATLWDSIKTLEPLNPRF
VSVTYGAGGSTRERTHATVKRITEETSLQAAAHLTCVDASKAEIEEVVTGYWDAGVRHIV
ALRGDPPRNDDAFEPFVPHPEGYASAADLVAGLKAIRPFEISVAAYPETHPEADCAQTDI
DNLKRKLDAGATRAITQFFFSPDCFFRFRDEAAAAGIDAEIVPGILPVSNVATTTKIAGL
CGAAIPRWMERLFEGLDELPAARQLIAATIAAEMCRKLYAGGVREFHFYTLNRAELSYAI
CHLLGMRAKKDER
>A0A8I0AWT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYERASVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLSTPPHVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PLASAKTAKWIRSNVPGIHIPDSVIKRLEGAEDQKKEGKQLCIDIINEVKEIEGISGMHV
MAYRQEEYVAEIVHESGVLKGRKPWTREANPADAMVADRLESIRGHKVEDQQQLAGLAAQ
HQPKNPH
>A0A1W1IE47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus pasteurii|TrEMBL
MKIRDMISKGEPTVSFEIFPPKSSYALETVFDTLGELKDLHPDFISVTYGAGGTAQSNTV
EIASRIKKDFGIESIAHLTGCTSTKEGMKRTLASIKDSGIENILALRGDIPQEKLTDKNW
NPEYRYASELIDDIKAAGDFSIGAACYPEGHVDSINKVDDLKNLKKKMDHGADFMITQLF
YDNDLFYQFKEKLDLVGIEQPVIAGILPVLNIKQVKRIQEISGCNLPPKFLRILDRYEHD
PASLQEAGIAYAVDQIIDLLSSGVDGVHIYTMNKPDATRRIMENISCVRKAVCRKEPQR
>A0A5C7S9P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp|TrEMBL
MSQIDENPLGVHLPLDPLPGHYSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLNEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDAVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRTDALVAERLHQISEGREENQQEMAEIAA
HHTPQAH
>G8NC12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus sp. CCB_US3_UF1|TrEMBL
MKIRDLLRAGRGPLFSFEFFPPKTPEGEEALFRTMGELKAFRPAFVSITYGAMGSTRERS
VAWAERIRRLGLLPLAHLTVAGQSRKEVEGVLERFVAVGVENLLALRGDPPQGERVFRPH
PQGFRYAAELVAFIRQRYGEGVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRVGIGIPILPGIMPITSYPQLRRFTEVCGASIPGPLLSQLERHQ
NDPQVILEIGVEHAARQVAELLQAGVEGVHFYTLNKSPATRMVLERLGFRAAP
>G3JDV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cordyceps militaris (strain CM01)|TrEMBL
MHIKDLLAETKRSGKPSFSFEYFPPKTSQGVQNLYDRMDRMYNFGPQFIDITWGAGGRVA
ELTCEMVLQAQAVYGLETCMHLTCTDMGMDKVNEALRMAYKAGCTNILALRGDPPRAQEK
WTATEDGFQYACDLVRHIRATYGDHFDIGVAGYPEGCDDNDNEDELIEHLKYKVDLGGTF
IVTQMFYDVENFIRWVAKVRAAGINVPILPGIMPIATYASFFRRCKHTGCNIPQNWLDLL
EPVKNDDVAVREIGKKLVVDMCRQLMAAGIHHMHFYTMNLAQATRMVLEELSWTPSAERP
LQQALPWKPSKGFGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRLKWGEPKSLRDIANTFVNYLNQDIDSLPWSEAPLTSEADSIKPALIE
LNQRGFLTINSQPAVDGVKSSHPVHGWGPANGYVYQKGYIELLVSPEIVDQVIPLVNGNP
SLTYYAVTKDGNLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFDAKSASRILVENVMDNWYLLNIVNNDFHDNSALFELFKDLKVDGLDTLVTVEVEKP
ATVQTGAAA
>A0A3D6A3R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MSKGESIGKILEKGKKLFSVEFFPPKDDAGGERMLKTAESFQPYDPDFVSITYGAGGGTR
VTTMRYAKLLQEEHGFEVMPHLTCVGHTRDELLTILEEFATAGFCNIMALRGDPPRGETQ
FRPIEGGFSYASDLVSLIRENFPHFGIGVGGYPEKHPEASNQVTDLKNLKTKVEAGADFI
TTQLFFDNQAFFKFVSDCKNAGISIPILPGLLPALSLGQVKRFCSMCEARLPHELEHHLQ
QSQESDQPGIGADWALDQVKELLNVGCPGFHLYALNKSKSTLKILEGLGRKRS
>G3JKM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cordyceps militaris (strain CM01)|TrEMBL
MEKITDKIAALPADAEYFSLEFFPPKTAMGFSNLRDRLHRMEQGLRPLFVNVTWGAGGTT
ADKSLELAELCQRELGMTTCLHLTCTNMSRKLVDKALDDAKALGIRNILALRGDPPRKEE
YRTASDDDDEAEGEAGDDFVMALDLVKYIRKKHGDYFCIGVAAYPEGHADESHPLGQCLE
HDLPYLVDKVQAGADFIMTQLFFDIEAYEQFETALRQHPSGAFRTIPIMPGLMPIQSFAM
IKRTAKLSHAAMPAAILERLHAVKGDDERVKAIGVDILSELVEQIRTVKRKTPGPRGFHF
YTLNLEKAVTFILERTHLIPDEPATQEDAVVDGGPTSGPFLQVNGHAIPPPRSHSRSTRR
HSSVGSDPHNRVIASTGRRTNPEWEATGAEAAVPAAQLNARANTLAISEGEGALGREATW
DDFPNGRFGDSRSPAYGEIDGYGVSLHMSVTQAVKLWGHPATTRDIDDMFVRHVRGELPA
LPWSEEELLAESSTITPHLAALNAKGWWTVASQPAVNGVRSADATFGWGPANGFVFQKAF
LEFFISSADWAALRDKLQRPGVREVVCFYAGNAAGDFVSSDSNSTVTATASSTNAVTWGV
FPGKEIVTPTIIEEVSFRAWCEEAFGIWGEWSRVYGRGSPSATLLSGIRDDYWLVNVIHH
DFVDHQALWDLLLA
>A0A0M8X098|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL B-3648|TrEMBL
MNPALLDDFSLEMTGKDVPGLEEARDSIPPGTRINITFLAGEDTATRLAAARAVKRLGFV
PVPHISARRLPSRPALEEFLAGLAADGTAENVFVVGGDPARPEGPYADALAVLRTGLLRS
HGVRHVGITGYPEGHPGIAEPALWSALTDKAAAIGADRFTGDVITQFGFDVDPVLGWLEA
LRARGVHLPVRIGVPGPAGVRRLLGYATRFGVGTSASVARKYGLSLTHLVGTAGPDRFLH
ALAGRYDPARHGAVKVHFYTFGGLRATAEWITRFRQARPARA
>A0A3P0NVS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Bp9017|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTDLCRRLIDAGVPGLHFYTLNAASATRTICDRLAG
>A0A0M8WY94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL B-3648|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLAYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPKLSNARF
PDALKERILSAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNSSTATLEIYENLG
LHHPPQA
>A0A160N2Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella thiooxydans|TrEMBL
MKDIYFDNRSAGPQLMPPISFEFFPPKTDEQRSQLDRTASLLKARRPEYASVTFGAGGST
LSYTGETVARLHREHGLEVAPHLSCMGGTRAEIAELLDGYRAAGYRRIVALRGDLPSGMA
SPGDFRYAAELVRFIREHSGDHFHVEVAAYPETHPQADDALADLHHFKAKVEAGADGAIT
QYFFNADAYFRFVDDVRRLGVEVPVVPGIMPIGNFSQLKRFSDACGAEIPRWIVKRMQAH
GDDAESVRQLGAEVVAQLCRRLLEGGAPGLHFYTLNRARPTLAILDQLH
>A0A350QZB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MAKGKSIREFLEAGKPLFSVEFFPPQDEAGGERILATAKSLTPHQPDFVSITYGAGGGTR
ATTMRYARILREEHGFEVMPHLTCVGHTRDELLEILDDFAEAGFCNVMALRGDPPKGETE
FKAVPGGLRYGSDLVALVRERFPHFGIGVGGYPEKHPEAPDMATDLSHLKTKVDAGADFI
TTQLFFDNRDYLAFVASCRKSGIEIPVLPGLLPVLSLGQVKRFCDMCGTSIPGGLRRKLE
AEDKKDQPEIGARWALEQVRGLLREGAPGFHLYALNQSASTLAILEGLKGD
>A0A4Z1DV94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus rubneri|TrEMBL
MTKQTPSLSFEVFPPNPEVGNAKLLRALENMQELAPHFISVTASNNKYNIKETTVALANH
IQNELSIPTIAHLPAIYLSKEKVADTLHELDQVGVHRILALRGDIIPGIEPLKDFRYATD
LIEFIKTEAPHFDVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENIHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVHHATKALFNHQPHFEGI
>A0A1H8N4S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. yr461|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLRIVHQELQPLNPDFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIRQHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A351MTT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MSSELLQRLRSPRPTVSVEFFPPKTAEGMSQMLAEAAKLRPLGIDLASITYGAGGTTRET
TLTAGRDLRALGYGVIAHLTCVGHSRSELEGLIDQYDAAGFSGILALRGDPPKGAPGFTP
HPQGLRYASELVELIRARVGLRLSVGVAGFPERHPDSPDAASDLRWFAHKVKAGADFVTT
QLFFDNADYLRLVADARAHGVTVPIIPGILPVRSLKQVRNFCSLSHARIPQELEAKLIEC
GENEAAQLSVGLNWAEKQIVDLLAAGAPGVHLYIVNRSDAAQELLVRLRGRGVIAPA
>A0A3R9DXZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVAEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNATPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A839EMR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium myrsinacearum|TrEMBL
MSFFRQSRRADLGTNIKVSFEFFPPKTEVMEERLWETVTRLAPLNPEFVSVTYGAGGSTR
ERTARTIKRILTETDVNAAAHLTCVDATKEEVDTVVREFAAMGVKRFVALRGDPAGGVGA
HYKPTPGGYENGADLVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVEKVRRAGIYIPILPGILPIHNFTQVTNFCSKAGTHIPAWLTERFD
GLENDPQTHALVSSAVAAEQVLDLVERGVQDFHFYTMNRADLAFAICHLIGIRPASGTLE
PALAGAA
>A0A6P6PCH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carassius auratus|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDTDRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPVGEDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYDDDLRHLKEKVDAGAHFIVTQLFFRAETFLRF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
HQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGDELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMSWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDAPPGSPS
>A0A7D5NCC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter sp|TrEMBL
MTPQPPVFSLELFPPKTLEGAEKLRGTRARLALLEPRFFSVTFGAGGSTRDRTLETVLEI
QREGHQAAPHLSCIGSTPDSIRSILEQYQAHGIRHLVALRGDLPSGMARPGTFRYANELV
EFIRAETGDWFHIEVAAYPEYHPQAKSPMEDLLAFKRKLDAGANSAITQYFYNFDAYAHF
IDECQALGIDVPIVPGIMPISSYSSLARFSDNCGAEIPRWVRKKLESYGDDTLSIHAFGL
DVVSSLCAKLLASGAPGLHFYTLNQVELTTTLWQRLGLSRRY
>A0A7X5H826|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus kayaii|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSIGRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGD
LPENGEKPKMYGVDLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFRQLKRFAVMTNVRIPSWMTRMFD
GLDDDPESANLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A8B5WIK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenzhouxiangella sp|TrEMBL
MTRSAPHLSFEFFPPRSDEQVSAFRAARDRLAALGPDYMSVTFGAGGSTRGRTRQTVLEI
QRETPIAAAPHISCMAEDEGSIRDLLDAYRDAGVRRLVVLRGDRPSGGGSGVFDYAIDLV
RFIRSHYGDSFHIEVACYPEHHPESASPQADLNHF
>A0A7T6Z789|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salicibibacter cibarius|TrEMBL
MKFLEKLKDEILIGDGAIGTLLYNRGYSGSIEDANRRAEDMVVSAHQEYIEAGANVIQSN
TYAANQLKLDNYGLGQEAARINTLGVRLAKEAANGKKEVYVAGTIGGIRDGRASSFTNQD
IKKATQSQAEALMAEDPDVILLETYYDLHELIQAVRIIKRLSPDMPVIGNVSLGDVGVLH
GGIPINDALLRLLNEGADVVGINCRMGPAQTIASLEEVSVPEGTYLSAYPNASLPGIQDG
RLVYQSNPDYFKNQAEEFRNQGVRLLGGCCGTTPEHIRSFKDKLQHQAPIVKARAKGSTV
REQASAEVGNTIQLDKEDPSIIVELDPPKSLTKIDTFIQGAKALHEAGADAVTLADNSLA
TSRIDNLAASTLIKQQAGAHPLLHIACRDRNLIGMQSHLLGLHALGIRDVLAVTGDPTKV
GDFPGATSVYDLTSFDLIRLIKSMNEGFSQSGRPLGLQTQFTVGAAFNPNVSSMEKAVKR
LEKKIVAGADFVMTQPIYDVETLQRLKEATAHLDIPIYIGIMPLINERNAEFLHNEVPGI
QLTEQVRERMAACRGDVQRGEEEGLAIAKELQVASLDLFGRLYLITPFLRYHITARLTSD
VRSGSAQKIRF
>A0A7X7D7P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MTRISDLLASGPTWSFEFFPPKTPEGMVALHDTVAQLSELAPDFVSITYGALGTTRSTTR
DLVVKINDEQSFPAMPHLTCVGHTRQDLVSLLEDYRACGVHNVLALAGDPPADGSDPGGD
FTYASELVDLAHEVDGFAVAVAAFPEIHPRSPDRETDRRQLAAKLGQSDFGMTQFFWEVD
HYRRMVDELADLGCETPILPGVMPFVNVAGTRRMSAINNCHIPDRLQERLDAVDGDAEAT
RKLGVEVATDLVAELLELGVPGIHLYAMNRAQSITEIYGNLGLRPDSL
>A0A062V9F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedens nitroreducens|TrEMBL
MSFREKLSSGKFIITAEISPPKGTDIADMIKEAGLIKDIVDAVNITDNQRAIMRMSPAAA
CSLLSNRGYETIMHLTCRDRNRLALQSELLGASAMGIHNVLVVSGDHTTKGDHEGAKPVY
DLDSVQLLGLIQKLNLGFDLSGNLLDGKPDFCSGAVASVELNEPGFMKLKKKRRMGAEFI
QTQAVFDTRKLSEFMNKIKSSEAFDGIKIIAGIIPLRSEKNAIFLNKNIPGIKVPEPIIE
QMRTAKDPVDKGMEIAAGLIKELQGLCDGVHIMPVGNHENTARILEMAEIR
>A0A7C9LZC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces luteolus|TrEMBL
MTGTEPDGAAARPRVPISFELFPPRTDAAAIALGRTIDRLAEVDPAFISVTFGAGGSSRD
RSLTVLRYMLEHTSVEPMAHLTCVGSSHAEANRLVREFLDAGITSFLALRGDPPVGAADA
EDAIGDLHSAAELVQLIHRVQEEREPFGQSRIPGMPGVTAIRERPRPERVAVAAFPTGHP
RSRGSNQDVDVLLAKEVAGANLAITQLFWHADDYLAFVQRARAGGVTIPILPGIMPVTTP
GRLARLEQLTGVPAPAELSIDLEIEPDADAQFELGVDYAARLAAEVLAGGAPGLHLYTFN
RHEAVLAVLDRLGLANAPAHAGTERNTRER
>A0A5F2A1C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira wolffii|TrEMBL
MKKILEIYKEARGPVYSFEFFPPKTEEGEEKLFEAVGELSKVDPGFITVTYGAGGSTRDK
TIRLTSELAKKYSLPAAAHFTCVGGNRDEIRTILAQIYDSGIRNLMALRGDPPKGEGQFR
KVEGGFGHANELISFIREEGFDFCMGGACYPEKHPEASSLEADVDRLKDKVEAGASYLVS
QLFFLNSSFGAFLDLVHKKGIHVPVIPGIMPITSFSQIERFKSMAACEFPPRLISDLEAV
KDNPSEFYKRSVDFSVAQCRELVETYRVPGVHFYTLNQSPASSDIVRKLKSS
>F0L657|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium fabacearum (strain H13-3)|TrEMBL
MPQQAKTWAKKRCMIRKRTKFKLHDISTSPAIAASIEASPAQVLGPASLAGIFPQGVRVY
LTDTGQASQDRLVDAAKHLRDLGYTPVPHLAARRISSRVEFEEQVKRLAGEAGVSDVLVV
GGGVATPAGPFASSMDMLSTGILDRCGINQIAIAGHPEGSPDFSDETATAALKLKYDFAE
RSDAAMRIVTQFGFDPARFIAWAEGLAASGIDLPVHIGVSGPARITTLLKYAALCGVGNS
IAYLKKNALSLTTLAKGHSPESVVGPIERHWQANPAGPIRQIHVFPFGGLQNSADWLAGR
GSWQTGDADFSAKRGTVAI
>A0A1H6HE07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum fulvum|TrEMBL
MNPVSSVELPIAAAAHRPVSVSFEFFPPKTDKMLDSLWEAVQRLVPLSPDFVSVTYGAGG
GTRDRTHEIVSRIAHETSLKPAAHLTCVGHSRGEVDDIARRYWDEGIRHIVALRGDMPDG
QPYQPHPQGYAYAVDMVAGLKRIADFEISVAAYPETHPDAPSADFDLDNLKRKVDAGATR
AISQYFFDPAVFLRFRDRCAAAGITVPVAPGILPVTNFAQVQRFSAACGAGVPDWLADLF
AGLDDDPETRRLVAATVAAQQCRILSAAGVDLFHFYTLNRADLVYAICHILGVRPKTA
>A0A2M9EKL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium NML120232|TrEMBL
MLPISFEIYPPKNDDQHAQLQRTLEKLKAHRPQFISCTYGAGGSTREHTAETVRLLTQQH
GLEGVPHLTCVGSTRQEIIQLLTQYQQQGVRRIVALRGDMPSGMLDPGELRHANDLVTLI
RESFGQHFHIEVAAYPETHPQARDALADIENFKRKVDAGANSAITQYFYNADAYFRFVDD
VRARGVDIPVVPGIMPISNFSQLQRFSESCGAEIPRWVSQRMRAFGDDSGAIREFAAELV
AALCQRLIAGGAPALHFYTLNLARPVGNILKRLQ
>A0A0Q4FZ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf17|TrEMBL
MTTISVSQLEEARNALAAPLYADVAGDVAVSFEFFPPKSEKMETQLWEAVRMLEPLAPDF
VSVTYGAGGTTRERTHATVARIAGETTMAAAAHLTCVEASKAEIDQVAQGYWAAGVRHIV
ALRGDAPGADGFVPHPDGYTNAADLTAGLARLHPFEISVAAYPEGHPDSASLDADMDNLK
RKLDAGATRAITQFFFEPETFFRFRDRASAAGITAEIIPGIMPVTNFAAVQKMAAMCGTD
VPAWLGRLFDGLEDHAGARGLVAATLAAELCRKLYAGDVRSLHFYTLNKAELAYAICHLL
GVRAKGTTA
>A0A1F8QHI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_54_18|TrEMBL
MERRLKAGEFVVTAEVAPPLSVSTRKLEANIALIRPYVSAINFTDSPSSTARMASWACST
LAIQQGAEPVMQIAARDRTRVGLQSEVMGAAALGVRNILCLSGDSMRMAPTPRGRMDVLD
IDSIQMLWILRRMRDEGRYLDGRSIKYPPSYFLGAAAAPFASEPRFQAIREHKKVNAGAQ
FFQTNLVFDVERLETWLDELAKRNIIDKVYILVGITPLKSFKTALYMNNELPGVFIPDPL
LKRMQAAGSGADEQGVQIALELIEKVRRLQGIHGVHLMAVGWEEIVPRIVTEAGLLAKQP
VIPEPTFVLN
>A0A5Q4GVU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenzhouxiangella sp|TrEMBL
MQLSFEFFPPKDQAQADILHKTQARLLPLRPEYVSVTFGAGGSTRSRTVATVLEIADQGE
VPVAPHISCMSEDLESIDSLLATYAKASISRLVVLRGDRPSGSRGGVFDHASDLVGHIRR
HWGQRFHIEVACYPEHHPESESPQSDLRHFGAKVAAGADGAVTQYFFNAECYLRFVDEAR
AMGVEVPIVPGIMPITNYRGLKRFSDMCGAEIPAWIDKRLAAWDRAGDSASLRAFGEEVV
TALCARLLERGAPGLHIYTLNRAAPALALCRNLGLTRP
>A0A2N4X9G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emticicia sp. TH156|TrEMBL
MAKVIEHLNNATDKPVFSIEIIPPVKGSNIDDLLKSIEPMMELKPPFIDVTYHREEYIFK
PQPDGQLKEIKVRKRPGTVGICASIMHKFNIDPVPHVLCGGFSKDETEDLLIDLNYLGIE
NVLALRGDFAKPYTSFIAKEDGHLYANELVTQIKDMNQGKYLHDESEYLSASSFCIGVAA
YPEKHFEAETLEQDIENLKRKIAAGADYVVTQMFFDNQKYFDFVNRCRAEGITIPIIPGL
KVLSTKKQLDVLPKLFFLDMPEAFRKEIAACENDKQAKQIGIEWCTQQCRELMNFGVPAL
HFYTMSKSDTTLAVARQIF
>A0A7M1NV11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parainfluenzae|TrEMBL
MSYANEINTLNQHLADTNKKINVSFEFFPPKNEKMESMLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGIEAAPHLTGIDATPEELKEIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIEAEIVPGILPVTNFKQLQKMASFTNVKIPAWLAKAYEGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHTLGHRPTTNP
>A0A0E9NH20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saitoella complicata (strain BCRC 22490 / CBS 7301 / JCM 7358 / NBRC 10748 / NRRL Y-17804)|TrEMBL
MSLTRASTWAASPSTTRAQPVHLSADPKGERIAYASNKSIFLRSLTNPAESIQYDQHTHP
TTVAKFSPSGYYVASADASGAVRVWDCAGTDQILKLETKPIAGALKDLAWDSESKRLIAV
GDGKERFGAAFTADSGNSVGEISGHSSVVNAVSIRQQRPFRAVTASDDTCVVFYTGVPFR
YSKTIRTHGRFVYDVAFSPDGEYFVSVGADAKVFLYSGKEGEVIGEFDTSEGHKGSIFAV
SWSPDSKFVVTASADATLKAWDISSQTCVETWSLSESDGPSVPDQQVGVVWTAKNEIVSL
SLCGDLNVFTRGNPKPAKIIKGHQKGITALTATEDAVWTGSYDGVIRSWDTKEGEAREVE
GETHTNQVVEFAQVDGGKVWSVGWDDTIRIADARVRSFDGSVIKTDSQPRGVSRRGGEVF
VAVVGGVVVYDAKGEKVGEVVTGYEPTAISANPMSEEVAVGGADNVVRVYTFKAGKFEEK
TTLTGNRAPVTVVAFSPSGTLLATADSSGKIILYSNTPSSTYEIKTTRWQFHNARITSLA
WNTDSTKCASGSLDTGVCVFDTEKVGKWVGGRGAHKDGCAGVVWSGVEVPPWLVLTPLNL
RETGPPLRTARPPAPPHSTRPPYDLAASQSRVLPKALGPEAVLARLMPTQVRRFTRNLEI
LEGCYRLGRDRHLAVIKPSLRGPFLFWFCASHDTALTFDMRHTFSFSCLDIHVHQRYLDT
STPRTLPIIFPSRSLLRTLNGPIRPLIFRSNRDRLSRLAAKVTGVKEGRRHHHYYSYPVY
PIEKIMKISDKLEQIPKDAPYFSFEFWPPKTTAGLENLHARLFRMSRLQPFFVTVTWGAG
GSTAALSLDLASACHQSHGLTTCLHLTCTNMDKSILDQTLLRARDAGIRNILALRGDPPR
GQEYWTATSEDFVYARDLVRYIKEQYGDYFCIGVAAYPEGHVEGSVVVERDVSKDLGYLA
EKVKAGAEFVLTQLFYDTEAFIAFEKELREFDGGVMKDIPVIPTIMPIQSYQSFRRMTKL
CGAFVPPELLARLDKVKGDDEAVKMVGVDVAVEMIQRIYEGTEGRCRGVHLCTLNLEKSV
GSVLEKSGLLDKVAEREDVPEVNIVNGQGRTVTIHESAIDDSAAPATNGMAHGNPGAKSR
RTSSLISESQNRVVVEEIRADMARLDLLTVAKDAGKVESPASRRRSNSVTLQEGKSVMGK
LATWDEFPNGRWGDARSPAFGELDGYGVTIHVPPQEALQLWQHPTDKSDISSLFVCHVKG
ELRAIPWSEEGLAPESEAIRQHLIGLNQKGWWTVGSQPALNAKPSADAIFGWGPKNGWVF
QKAFVEFFVSPEDWRELYERLKEQPQISFYAGNRRGDHYSNMEQSDANVVTWGIFPGREV
AQPTIIEEVSFRAWKDEAFAIWGEWEKIYPKGSPSAELINKIGENYLLVTLVHHEFLEQN
ALWEFLGVVNNE
>A0A1H9YZJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanococcoides vulcani|TrEMBL
MLSTFNDALNSDRFIVTAEVAPPKGTDISATLEDADLIRGWVDAINITDNQHAVMRMSPV
VVGKLLMDAGHEVIVQFTCRDRNRLALQSDILAASVLGIRNLCVMTGDYPTKGDHVGAKP
VYDLDSVQLLSLITKMMDGHDMAGNELAGAPSFTIGAVSNTEAARRMQMIKLKKKIDAGA
QFIQTQAVYDVEGFGEFMDSFTHPDVPVIAGIIPLRSAGMARFMNGNVPGIRVGDELISR
MEDAEDPVQEGLEIAAESIRELRKMCRGVHMMPIGGNSNTPKLLEMAGISALQ
>A0A6A3BLT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hibiscus syriacus|TrEMBL
MPVEKIDHALETIKSNCIQNVIALRGDPPHGQDKFVQVEGGFACALDLVKHIRAKYGDYF
GITVAGYPEAHPDAIGDNGVATPEAYQNDLAYLKRKVDAGADLIVTQLFYDTDIFLKFVN
DCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKIPDEITAALEPIKDNDEAVKAYGIHL
GTEMCRKILANGIKTLHLYTLNMEKSALAILMNLGLIEESKISRPLPWRRPANVFRVKED
VRPIFWANRPKSYITRTIGWDQYPQGRWGDSQNPSYGALSDYQAYKMVELCYLFLIDDFQ
SILGPFNIFLLLRSSPWSELDGLQPETKIIHEQLGEFVQFKPSFFPALRLSIVKAGAVLD
LNCSDMMALLVGVAPEGMFTSKSFPSLTYVAVYKNGNLVSNISVKDVNAVTWGVFPAKEI
IQPTVVDPASFVVWKDEAFEIWSRSWSALYPDGDPSKKLLDQIQNSYYLVSLVDNNYMDG
DIFCVFEDL
>A0A2K5R143|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cebus imitator|TrEMBL
MVNEARGNGSLNPCLEGSASSGSESSKDSSRCSTPGLDPDRHERLLEKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCHQRLEEITGHLHKAKQLGLKNILALRGDPTGDQWEEEEGGFNHAVDLVK
HIRSEFGDYFDICVAGYPKGHPDAESFEADVKHLKEKVSAGADFIITQLFFEADTFFRFV
KACSDIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVRLCRELLASGLVPGLHFYTLNREVATTEVLKHLGLWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKNYYLFYLKSKSPREELLKM
WGEELASEDSVFEVFVHYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGVL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPGLQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYE
EESPSRAIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQHEREAEAP
>A0A106C050|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella frigidimarina|TrEMBL
MAFHHAQHAQSLNQSLSELNDINVSFEFFPPSTPAMEEILWNSIRRLEPLNPKFVSVTYG
ANSGVRDRTHSVIERIQKETNLLAAPHLTLVDASDEELVELAKHYWNSGIRDIVALRGDL
PEGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDARNAQADLINLKKKIDAGANRAI
TQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVTNFKQTKRFAGMTNVAIPHWLHRQFEG
LDDDPATRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A009NEC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 1475718|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGEHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A1Q8EGS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas chlororaphis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERIQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>S0FX01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotignum phosphitoxidans DSM 13687|TrEMBL
MSFKAKLSSGERVILAEMDTPKGVDISNMISHARFLKSRVDAVVLPDLDTGVMHLNALAG
GAILTQQGLEPVIHVYGRDRNRMALQGDLLAAHVLGIHNLMVVQGEEMINGDHPDAKIVD
DVDELGILKMIQTLMAGTDLAGFELHGKPEFIPGIAVPPIADEDQLTQAVADAGAKIAAG
AGYIVLQPVFDLDFYKKIIHAFSSLNVPVIASVFLLKNVGMARYISINDPTSRLSEDVIR
RIRQAKDRDTECVAIAGEMIRSLKEISQGIKISALGWEDKLPAILDSAGL
>A0A653V8B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium sp. 9AM|TrEMBL
MPSQDQSLVDAIRGPSPSYSFEFFPPKDDEGEAVLWQTIADLESLEPTFVSVTYGAGGTS
QERTVRITARIAEQTRMRPVGHLTLVAQTRGEIESVLKQYAAAGVDNVLALRGDPKGGPR
APWEPHPDGMEHAIDLVELATGLGGFRIGVAAFPEGHPDAASLDHDAQVLVDKAEAGAEY
AITQLFFRASDYFDLVERVRAKGCDIPIVPGIMPILNFAQVARMAELSGAELPREVLDEV
EPIQDDKPAVRAKGIELATRLCRDLLDGGAPGLHFITLNRSKATREIFEALRADGLV
>A0A1H9LHP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter rhizosphaerae|TrEMBL
MKITDHINNAKGKTLFSFELLPPIKGQSIQWVYDAIDPLLEFEPPFIDVTSLREDYIYKE
QDNGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARQADAAFIPTRGGHAYATDLIEHIKNHNAGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNADFKYLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTAKQLIALPKIFHIDIPEDLSDAVENSKTAADIREVGTEFMIKQCKELMDFGVPVLHF
YTMGKPEQTKRIAKAIF
>A0A1F9EZ21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_19FT_COMBO_46_12|TrEMBL
MKLEESLKCKRFIVTSEIQPPIGTGIQDLVRNIDKIRGRIDALTVPELKIEGLVTDTMGT
CRALKDQRFDPILQTTCREKSRVDIQDHLIKACESGIENILTFTEDYRITGDSLQEIMFF
HVDSGKLFSVIENLHEGHDISGRELPVRPRFCVGSGIDSSWGKKVPDLELKEMEDLAGLG
TQYFLTTPIFDLDSFNQFMNRVGPIRIPVIAEIILVRSAEMGLFLNKHVKPGMVPNHIIE
KLAKAPDKEKASIEIVSDLVKGLKDLCQGVHFIPIGAEDRISKYLDAIKL
>A3PHY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cereibacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)|TrEMBL
MARPRISFEFFPPQTLEASFRLWETAQMLAPLKPDFVSVTYGAGGTTRKLTHDAVETIHT
HYKLNVAAHLTCVDATKAETLEIAASYAEAGVTEIVALRGDAPKGVDRFTPHPEGFASSV
ELVEALAATGRFKLRVGAYPEPHPDAADTLADVRWLKRKIEAGATSAITQFFFEAETFLR
FRDLCAKEGITAPIIPGILPIENWSGVKKFAARCGAQVPGWLDDAFDHAKRDGREELFSV
ALCTELCDRLLSEGVEDLHFYTLNRPTLTREVCHALGILPEVALQNVA
>A0A537WV69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDSPPGRPTSRDAKAGAAPPGWDTAPMDAAAFRSLLAEGPLLADGGMGTSLIARGVPVDA
CMEELNVRASARVAEIHASFVGAGARLVLTNTFGANRYRLERHGLADRFAEFCAAGVALA
RDAGAPIVAGSMGPLGVRLQPYGRVHPEDAFAAYREQAAALADAGVDLLVVETQSDLREL
EQGVRAARDAAPNVALIASATFTRDDRTLLGSPPEEVAQTVVSLGVDALGVNCGEGPAQV
LRIVRAMRRTAGASSAPIVARPNAGGPAEVGGRFVYPATPEYFGEIAQALLDDDVAVVGG
CCGTGPAHTMAIGAALRDRAPHARIEFPEADHGDRILDVVTVTPPTKLEAKLATGHFVVT
VEMEPPRSFNAARLVAAAETLRDAGADAIDVADSPMAKMRMSAWAACRLIHEQAEIETVL
HFPTRGRNLLRLQGDLLGAHALGIRNLFVCVGDPVTIGEYPHGSNNVDVTATGLLSMITH
AFNAGVDRSGTSIGAPTSFFVGAAVAPSAPDLEREARLLARKAEAGARFVLTQPFYSIDP
LLALRETYEKVADEPLTVPLVAGVLPLMTSRHAEFLHNEVPGIEIPEASRDRMRSAGDDD
EQAWREGAAMAAELIAALREEGVAGVYVMPQFGRYDRAAEVVEAARGPATM
>A0A7W1JXX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPAEVQTRNRFLERLEKGPVIVADGGMGALLSAAVPRLRSPEEANLRAPDAVVSLHVSFI
NAGSDLIETNTFGANRRKLSHHFLEDELESINSAGVKLARDAREMTGRDVFIGGSIGPLG
EPATSRVRRELFAEQAAVLDGRGADVFMVETFYDLEEVVDAIEAVRSVSSLPIVALLTFD
ESAETLAGVTASEAAARLMELDVAAIGANHGAGLLAALAALEQMGQNGKPLAALPNVGLA
SMTGGRVIYPHATPEYFGEFAAHARNLGAKVIGGCCGTTPAEITAIRAAVEDERKPRAPL
VFDAPELVVALGEEQRETGLSRALGAGEWVVSVQLDPPLGGNSAGLVEVSAALKDSGRVG
WVDVNDNATARAGMSSLMVSATIERRAEIETIPHLTTRDWSVMGLESMLLGAHAEGVRNV
LAVTGDPPEVGDYPGARGVYEIDSIGLTQLMTNLNRGEDFNGRPIDAPTSFFPGVAVNPT
PDDMDVELERFEKKLEAGAKFAMTQIVFDVDYLDAFVERLGGEWPIPVLVGVFPLTSHRL
ALRLHNEVPGILVPQSLQDALERAGSDAADVGFQHARELIEASRERAAGVYLVAPFRRPL
RVLELLAD
>A0A662T361|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Geothermarchaeota archaeon|TrEMBL
MAMSVVKRFKELLRERRTPITYEIYSPRGCNVDQYVRAISDFKDELSAVNVPDNPLATLR
VSSIAYASLVMNSLKVDVIPHITCRDRNLLALQSEILGAHLLGIRNLLIVSGDRPIGRTR
ELKYVWEANPIRLCEIVKKMNQGQIFCGEFVEMESKTDFFVGGIVIFSRKNEVNYISRKI
SVGFDFFQSQITFNADEVINFFEEAETSGARIDRPVLISLSPISSGNFLYKLT
>A0A7X3F842|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas monteilii|TrEMBL
MSLLKTALREQNFVCVTEFVPKPSAERFAAMEAIMVRAHLCGWPMTIAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DGDKHQEAMHWMRRQARPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETVQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQTRIHTLDQWAPA
WRASWQMPGLPAVTFHPPQAGWRQGESRVDASLTEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPLWSTPVGAQVLHKMERAVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAPQTP
RRLSPQPTPRSQPES
>A0A538M8K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDAAVFRSLLAEAPLLADGGMGTSLIARGVPVDACMEELNVRAPTRVAEIHASFVGAGAR
LVLTNTFGANRYRLERHGLADRFAELCVAGVALARDAGAPIVAGSMGPLGIRLQPYGRVH
PEDAFAAYREQAAALADAGVDLLVVETQSDLRELEQGVLGARDAAPDVALIASATFTRDD
RTLLGSPPEEVAQTVVALGVDALGVNCGEGPAQVLRIVRAMRRTAAGAGVPIVARPNAGG
PAEVGGRFVYPATPEYFGEIARALLDEGVAVIGGCCGTGPAHTTAIGTALHDRAPHVRIE
FPEADHGERILDVVTVAPPTKLEAKLATGHFVVTVEMEPPRSFNAARLVAAAETLRDAGA
DAIDVADSPMAKMRMSAWAACRLIHEQADIETVLHFPTRGRNLLRLQGDLLGAYALGIRN
LFVCVGDPVTIGEYPHGSNNVDVTATGLLSMITHAFNAGVDRSGTSIGAPTSFFAGAAVA
PSAPDLEREARLLARKAEAGARFVLTQPFYSIDPLLALRETYEKVAGEPLTVPVIAGVLP
LMMSRHAEFLHNEVPGIEIPEAARDRMRSAGDDDDRAWEEGAAMAIELIAALREEGVAGV
YVMPQFGRYDRAAEVVEAARGPATM
>A0A7W1KUB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAVRLGRRRTGTLPDAQRIALRALIAAPKFELIPLKNALEAAHALPDRATVTVTASPSHG
IESTIELAEQMVAAGHEAVPHLSAHMIRGRAHLGELLERCRAAGFREAFVVGGDAKDRGE
LHDGLALLRAMHELGHPFETIGVPGYPEGHPDISGERLLEVLLEKQRYASYMATQMCFNP
GAIVTWIAGMRRQGVTLPVHLGTPGVADIAKLMTISARIGIAGSARYLKKNKRMVGHLLT
PGKFGPDALLEGVAPALADPGAKVEALHLFTFNQVGATVEWQRRMLASLDD
>A0A7X3YV08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0678_bin_10|TrEMBL
MHIAEVFRQSQPAISFEFFPPKSEAASESLFHTIQKLIPLKPAYVSVTYGAGGSTRELTH
DLVVKLHNETNLTIVSHLTCVKSRRDEIFKILQRYDEHGIQNIMALRGDPPTQEPWDPAE
QDFHHAVELVAFIKEHFPHMGIGVAGFPEGHPDTPNRLQEIEHLKAKIDAGADYICTQLF
FDNRDFYDFCERCRLAGIRVPIIAGIMPITSLKGMKRMAELALGARFPGRLLRALASAKD
DAQAEKIGTHWATEQVLDLLDNKVLGVHLYTLNRSRASLQIYETLGLQRVDMPME
>A0A7K0THM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTIPSVSFEFFPPKDSEGESRLWEAMMNLRSIAPDFVSVTYGAGGSTRDRTIEITTHITE
RTSIPTVAHLTCVGSTQEEIGEILMRYRDAGIKSILALRGDPPGGPSTPWTHTPGGLDHA
DELVALAAEFGDFTIGVAAFPDGHPASHGNFDQDVNVLLRKEELGASFATTQFFFDVNKW
ISLVNRLKERGSQLPIIPGILPISSVKQLVRMAELGGTPIPDDIHAKFLSIESDDAAVKA
LGIEIATKLCIELLDAGAPGLHFYTMNSSAATREIWENLGLKR
>A0A7W0QLG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MEAPRQKAPVLAELLARPRYEVIPLAGAEEAVLEHVPTEVTVTVTTSPKKGLEPTLELVE
KVAAHGYAVVPHLAARHVRDRGHLAELIERLRAAGAKDVLVMAGDAEQPAGEFDGSLPLL
RALAELGQPFHDVGITGYPESHAFMSDDATIKSMFAKEEFATYIVSQICFDPQVTAAWVA
AVWKRGTRLPIYIGLPGLVPRSKLLRVSARIGVGDSIRFLRKHRGWLGRTFRGAFDPGPL
VEGLEESLDRPQPNVVGFHLFTFNDLETTERWRQEQLQRLRSPVPADADALR
>A0A7W3JR65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium halimionae|TrEMBL
MTLTACPKSMTFGPCGGVNEDSSCEVDPAPCVFLSRHLPVSWSEPATAATPNAATAAAKE
VGRIMRRRPLVVTGFPVRAMTSCDVPRVADVLRGRADVVLSGDAGTSRTQFPPSYRAFLM
AQAGVRVWMGVNARDRNRAALDREMLSLQEIGIAGIHCVTGDHTFTGDRPDARAVFDLES
TTMLSRARSLGLLTSFAESPAAPPIEKRGARVREKQRAGGQMCWPQYCGDVSDVEAFIAT
CGDAGADVPVLPGVPLVVDREGAILLASFHAAKLPTGFISRLLNAKDVRAEGVRAAVEYG
ESLLTAAGVGGVVIAGGTRHGDELAYAADLATVAEALGGGS
>A0A7W1K2Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSAKGGRLAAFLDAGEFVVTSEVVPPRSGDGSKVREAARGLVGYVDAVNVTDNPSASPHM
SPLAGARFVHEAGAEPTLQLVCRDRNRLAITADLLGGWALGARNILVLGGDPMDVGDHPD
AKPVFDLGPNQVVELARRMRDEGITGADAEIADPPRYLIGVADVPVSDPYDPAKLEAKLD
AGGDVVWTQIVYDVDRLGEWADLVRPRGIFERAKVLVGLVPLRSLKNARFMDGLFGVHVP
QTAFDVLETAGIEAERAGLEFTIDVAGRIRQIDGISGLHLMGIGRDDLVRTVIEEAGLFP
RPTSV
>A0A7V1RJS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRTSERALRHRSGDLRPAERQTLARLVAGARFELIPLANALEQAEALPPGAPVSVTASPS
RGMWATVELAAELARRGHPTAPHLSAHMIRDRGELAELLARCREAGITEAFVVGGDAKEA
GAFPDGLALIRAIRELDGPFERLGVPGYPQGHPQIPEDVLQAALIAKAPLASWVTTQMCF
DPAAIVAWIGRIRTSGVELEVHLGVPGAVELGKLMAVSARIGLADAARYLRKNRSVVGRL
MRGSFGPDGLLAALAPTVADAGAKVGGLHVFTFNQVASATAWQRAMLEELEGTP
>A0A6I3N020|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARITELLARGRTFSFEFFPPKTDAAQLSLGRTIAELETLHPSFVSVTYGAGGSTRERTR
DLVTWMRRETTISPMAHLTCVGHTRSDIEEILQAYVDAGVENILALGGDPPTDPADVRPS
DYQFASDLVAELQAAGQFSIGVAAHPEVHPRSSSRTEDREFLAQKLRRADFAITQFFFEV
EHYVRLVEELAALGIDKPIIPGIMPVTNKSQVQRMAEMSGAAFPQDLSERLAKVEDPEEV
RRIGVDAATELCAQLLDAGAPGLHFYTLNRSSATREIYANLGLPVVSSAS
>A0A537YIL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
KLCQALLDGGAPGLHFYTLNRSTATREIYANLGLG
>A0A538M4F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSWRFWRRWRASGLTEEQRAALKSLVADARYELIPLSSALEHAAALPPGSQVTVTASPSH
GIEATFDLAEAVAAQGHDVTPHLSAHMLRDRAHLADLLERAQANGLRKVFVVGGDTRDRG
ELHDGLMLLRAMDELGHPFEEVGVPCYPEGHPDISDERLLEVLREKQRYANAMTSQMSFN
PAAVTRWVGEVRDAGISLPLHLGVPGVADLPKLMRIAARIGVADSARYLKKNKQLLGHLV
RGGSFGPDEFLEQLAPMLADPVADVRVLHVFTFNQVEQTAAWQRGMLDELSA
>A0A2E6XUK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MALSSGYMAGVPERLAAGRTLSFEYYPPAGAAARRGALLTATRLARRHPDFVSVTYGAGG
GDRGRTREMVAHIAFGHVSGRHRCPVVPHLTCVGHTRAEIRGLLADHMEVGVGDLLALAG
DPRPGEPPGDFRYAADLVEFVRTETDFSVGVAAFPEVHPDSPDRVADRRHLAAKLEMADF
GITQFFFDSRDYRLMVDELSDLGCTTPVLAGVMPVTNPESVKRFAKMNGTRTPKELWNRL
EAADADERLRIACDQAASMIADLVEMDVPGIHLYSLNVPEAVEGVLDRLGEGYFSTAGRP
LGTGL
>A0A3D3BP30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTAETLASAVRGFSIESVPQDADRIDDFRDHVPTGTRVFIAWPPKATPESIVKSARKLHE
QEMVPVPHIAARRVPSQEFLRAFVGDLVAQAHVREVLVIGGDPATPEGPYTDTGSLLRSG
VLNEFGIEKVGVAAHPEGHPVMSGAVSREVLADNLAAARDHGMSVEAVSQFVLDPQAIDS
WHAEVYSSLAQGAPLLIGIPGLVSGTRLLKIANACGIGESIGLLRKNGLRMAKTVIGNSS
TQTLVEGLAPLANRATDVGGFHFYTFGNFEQTAAWACEAASTPAAAAG
>A0A3C0LAD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MNLREKLAANKFVVTVELDPPKTLNLERILTEVNSTNFRKLVDAVNVTDCPLAKLRMSPI
ALSHIIQERIGLEAIFHITCRDRNLLGLQAELLGASALGVKNILALTGDLPEMGDYTRAT
GVFDVDSIGLVKMVNKLNNGYEYSGNELKDKTDFFIGIAVNPTAQDLKKEIARFEEKLSA
GTNFVQTQPIYDIGLLERFLKLTAHINIPKIIGIMPLKSYKMVEYLNKNLPGIFVPPEVK
ERMRGKDVEEGVKISRELISKIRKFKEVTGIHIFPLRDMDLVCRLLS
>Q0SHQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus jostii (strain RHA1)|TrEMBL
MTFDSVRGRASEGWVTRTPSIVDRIRSSSDGRVPFSVEFSPPRDEAAEARLWRAVREFER
MGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWEKHPDGVEYAEDLVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSV
RRVLELSGSRLPAHLEKRLATAAGDGPEENRAAVREIGIDVATEMSERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSGVADPAPVTPARVS
>W2U8W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus sp. NMX2.A1|TrEMBL
MKIRDLLKAQEGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRDRS
VLWAKRILDLGLNALAHLTVAGQSQEEVAGVLDRFVEAGVENILALRGDPPQGERVFRPH
PEGFRYAMELVAFIRSRYGEGVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRMGIEIPILPGIMPITSYTQLRRFTEVCGASIPGPLLSRLERYQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGFKPQP
>A0A538G0K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
ANRRKLAAHYLENELETINSTAVRLAREAREVAGRDVFIAGSIGPLGESATRRVRTDLFA
EQALVLEGRGVDVFAVETFYDLEELEDAVLAVRSVSSLPIVALMTFDETAETLAGVTAAE
AAERLNNLDVAVMGANHGAGLMAALAALEQMGGDGKPLAALPNIGLASLAGGRVVYPHAT
PDYFAEFAAHARDLGARIIGGCCGTTPAEIAAIDEALAGERKPRARLEFAERELLVSLGE
ELLETGLARALREREWVVTIQLDPPLGGSSKGLVELAHAIGESGKAGYVDINDNATARAG
MSSLIVSATIERQAGIETIPHLTTRDASVMGLESMLLGAHSEGVRNILAITGDPPEVGDY
PGAQGVYEIDSVGLTELMTRLNRGEDFNGRPIDAPTSFFPGVAVNPTPDDLELELERFHA
KVEAGARFAITQIVFDLDYFDRLTERLGGSWPIPVLVEIFPLTSYRLALRLHNEVPGIVV
PEALQLELQNAGANAAEVGFSRARELIEGARERAAGVCLVAPFRQPLRVLELLE
>A0A2E4AVY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MFENNRPDKKIQQQLLEGMTYELIPLKNVHDQAKFLPQNSTMSVTCSPAKTIDDTLDLCE
SFSADGHITIPHFAARMVEGEEHVDSIIDRVHKLGIRKIFVIGGDADQRGPFYDAPSFLQ
ALVARKPDIDTIGIGSYPDGHADIPNSSLDQALFEKQEIILGAGYEGYIATQMCFDAKKI
TEWLSEIREAGISLPCHLGVPGAVDTKRLLTISLRLGIGHSTRFLKKNRATALRLLSPGK
YDPNKLLSPLSRNALDLGITGVHCFTFNSVDTTEEWRQKVIKKLSS
>A0A268UBP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. 13S00482-2|TrEMBL
MIGLEYIPKQKEMDLELISNWIDKIKPDFILIPDSPNSRPTPESCIISMLWKQRLAIDVI
GTIAGSGRRKDRIESTLLALKYLQVNKVALIGGDSPSIGDLNGIELIKKAKDILGEDSVI
ISGSKAILDTEEKHKLKTKIEAGANIIISQPIFEPKIAQKFLDDFETIAKGSNAMGMISF
FPIYESAFCKKIINNNLGFEIPQAYIDEIKNNPIKTNIKLYEELCSIGADIHISGGKNSF
LQEFFDNFKS
>A0A4D6XYP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MLSSQTNYNLEKQKGNLINSISISFEFFPPKNEESITRLLSDINEFTTLNPSFISITCSP
HKKTTNHTYKLIKKIKEQNRIHTVPHVTCINHKKKELKTIAKKYWKNGVKSILALRGDKI
KNSNSNTMYAIDLINILKTTGNFNVYVAAYPEVHPEAKNPTFDLLNLKNKFLAGANSAIT
QFFFNAETYLRFRDKCSKIGIYNDIIPGILPIVDIQQLKRFSSMTNVNIPIKIFKLLDNL
TPNSIQFNIISSYITNSIIDVLYREGVRKFHFYTLNKLYLAHSIAYILKMKNFSEK
>A0A022J4H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 1564232|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGEHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>F2NP99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinithermus hydrothermalis (strain DSM 14884 / JCM 11576 / T1)|TrEMBL
MKIRDLFREGRPLFSFEFFPPKTPVGEAALFKTIERLKPLKPAFVSITYGAGGSTRAKTI
EWARRIKFELGLETAVHLTCVGASRREIKVLLDQVEAAGIENVLALRGDPPRGETEFKPA
PDGFRYASELVRFIRAEGYPFSLGGAGYPEGHVECRDREQDLLHLKHKVDSGLDFVITQL
FFDNHHYFDFLERAERVGIRVPIVPGIMPITNIQQVQRFTKMCGASIPRSLLAELERFGD
DDQAVLAIGVEHATRQCQELLDAGVPGIHFYTLNKSPATRLVVRNLRVPVRKTA
>H1HF89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. animalis F0419|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSLEKPDYISVTYGAGGNTKGRTV
EIADRIKRQNGLESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDKELEKGD
FNYARELIEYIHKKKGDKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRHE
>A0A538C1D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDEILAAQAPVFSFEFFPPKTPAGEQNLYAALNELKALEPSFVSVTYGAGGSSREKTI
EIVKRIKDEFGLEAMAHFTCIGATVGQLRETLDEMQLAGIDNVLALRGDPPAGQEDWIKT
EGGLEYSHELVQLIDRNYPFAIGAACFPETHIHAESPEADLRYLAEKVQAGADFLITQMF
FDNDAYFDFVARARAAGVSVPIIPGVMPITRVGQIERMAQMCGAAIPDGLREELHARGED
AEAVLDFGVAYATLQCSELLAAGAPGIHFYTLNRSPATRAILSALKLARPWERAIYPASI
SSPSATRGEPSGAS
>A0A7U6Y8M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium LM-1|TrEMBL
MTVSERILPLSVSVSFEFFPPKTEKMQEQLWESVARLAPLQPGFVSVTYGAGGSTRERTH
DTVLRLKREKGLAPAAHLTCVAASKAEVDDVARLYWQEGVRHIVALRGDPPDGGKYQPHP
DGYAYAVDLVTGLKRIADFEISVAAYPESHPEAASAEADLDNLKRKIDAGATRAITQYFF
ETSTYLRFLERARKAGIQVPIVPGILPVTNFAQVQKFSAACGTNVPAWMADLFKGLDDDP
DTRRLVAATVTAELCRALAGEGVEHFHFYTLNRADLVFAICHILGVRPKEQ
>A0A061P7E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomicrobium sp. JCM 19039|TrEMBL
MKFIEALQKTIIIGDGAMGTLLYSQDITGSIEQANLYAAEQVYRSHLEYVKAGANLIQAN
TYAANRLKLKNYGLESQVTRINEAGVQLAKRAAAHSDGTYVAGTIGGIRDGRSSEWTDEE
IDNAILEQTKALLASSPDVMLLETYYDLHELIRAIRLIKEQDASIPIVANVSLGDVGVLH
GGILLQDALQRLKSEGADVVGLNCRMGPAQTIASIKESDIPTDLLLSAYPNASLPGIRDG
RLVYQSNPNYFKSQAVSFRNLGVNLIGGCCGTTPEHIRALKDQLKGKAPIKRSQTSNNHF
VNLKRPESKDHPVSNQKVPSVIVELDPPKSLSKLDVFVDGAKALTEAGADTITLADNSLA
TSRVDNVASATLIKQRTSANHLFHIACRDRNLIGMQSHLLGLHALGITDVLAITGDPTKV
GDFPGASSVYDLTSFDLISMLKEMNEGFSHSGRSLGVKTNFRVGTAFNPNVSSMEKAVKR
LDKKIKLGADFVMTQPVYDVDTLYALKKATTHINVPIYVGIMPLINSRNAEFLHNEVPGI
TLTKQVRERMQSCGQDVQRGEEEGLQIAKELQQHSLSLFERVYLVTPFLRYHITASLVQD
ANAQLSKQKLNTLH
>A0A833D3F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiaceae bacterium|TrEMBL
MSDSTARPPAAVAGGPVKVSFEFFPPKSPKMELSLWEAVHRLAPLGPAFVSVTYGAGGST
RERTHATVERILRETSLVPAAHITCVEASRNEVDDVARAYWAAGVRHVVALRGDPPAGPG
VRFQPHPEGYSCAADLVAGLKRVADFEITVGAYPEKHPSSPTVMADIDNLKAKVEAGASR
AITQFFFDNSHYYRFLDRVRGRGINVPVTPGIVPIHNYTQVATFAQRCGATVPESLRRRF
EGLESDPETTRLVAATIAVEQVMDLVDHGVRELHFYTLNRANLVYAICHLLGLRPMPVAS
AAAA
>A0A7K2QEL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7760|TrEMBL
MSARPTPYPERPAQAPVIGGGLAELLRRVRYEVLPAKATEDKVLAHVPAGVPVTVTASPA
KGIGPTLDLAVRLAGHGYRVVPHLPARQITDAGHLSDIVDRLVAAGIEDVFVPAGDADPP
AGAYDAALPVLRRLGELGSPFAHVGITGYPESHPLIADEVAVRAMSDKQPHATYIVSNLC
FDPATLRQWLGRVRRRQVLLPVHVGVAGPVERAKLLSMATKIGVGESAKFLTRHPSWFLR
FAAPGGYSPERLLRRSAPALGAPESGVAGLHLFTFNQIAETERWRRAVLDRLAG
>A0A6A1VZ25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morella rubra|TrEMBL
MKVIEKIRAGLAEEGNVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPAFCDITWGAGGST
ADVTLDIANKMQNIICVETMMHLTCTNMPVEKIDLALSTIKSNGLQNVLALRGDPPHGQD
KFVQIQGGFACALDLVKHIRDKYGDYFGITVAGYPEAHPDVIGSDGVASEEAYKNDLAYL
KRKVDAGADIIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPAEITAALEPIKDNEEAVKNYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMP
KNSRTWQNLGLIEETKILRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPR
GRWGDSRNPSYGALADYQFMRPRARDKKLHEEWATALSNVEDIHEKFKKYCLGKLRSSPW
SELDGLQPETRIINEQLVLINTKGFLTINSQPAVNGEKSSSPSVGWGGPGGYVYQKAYVE
FFCSREKLDALVDQCKAFPYLTYMAVNKGGSWISNVGQTDVNAVTWGVFSAKEIIQPTVV
DPASFVVWKDEAFEIWSRGWACLYPEGDPSRKLLEEVQSSYFLVSLVDNDYIHGDLFSVF
AEF
>A0A8H3F0E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heterodermia speciosa|TrEMBL
MHIKDKLAEAQRTGKPVFSFEFFPPKTAQGVQNLYDRMNRMHDLGPAFVDVTWGAGGSLA
QLTCEMVHVAQTHYGLETCMHLTCTDMEKAKVDNALSEAYRAGCTNILALRGDPPRDNEK
WQAVEGGFHYAKDLVKYIKATYGPHFDIGVAGYPEGCDDQQDPEILMEHLKEKVDAGGTF
IVTQMFYDVENFLDWVRKVRARGITVPIVPGIMPIQTHAAFLRRAKWSNCNVPQHWHDAL
EPVKNDDAAVREVGKGLVAEMCQKIIDAGIMSLHFYTMNLAQATRMVLDELGLVSQNGTP
TKALPWRQSLGLKRREEDVRPIFWKNRNNSYIQRTQDWDEFPNGRWGDSRSPAFGELDAY
GIALKGTNEQNIKLWGKPETLKDVANIFIRYLENDLNSLPWSESAITSEADSIKAELVDL
NKRGLLTITSQPSVNGEKSTHPIHGWGPTGGYVYQKAYLELLIAPELVVELINRIDQDTD
MTFYAVNQAGDLRTNAPSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGSDWA
NCHPSTSPSRKLIKNIMDNWYLVNIGRILNAAMANRVRCNVLTGCLVHNDFHSTHGIFEL
FDGLHTEGMDDMAKTTNHTNGTHKATAQLNGNLKPDNPDVFNQVNT
>A0A1S2G0F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHLSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKI
YPDSIEKVLHFSGKARDIQDFELFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFEGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
SGKEFSPEITHFSCQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKDKLIPTVPLETRGTSSWKNWYLATEA
>A0A7D6ZYZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEHFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQVGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEITRFSCQPTSKQLIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILREKLIPTVPLETRGTSSWKNWYLATEA
>A0A182I3A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles arabiensis|TrEMBL
MATTNTVTNEEQSNEHSLRTKMDRIFNSSTTTGPVPVHYSIEIAAKDDFDIGQLERLTPQ
PVFCALPWVSDDNLRYADDFLRSSTLQLTARLRENQYTVLNNVSCYNITEQQVDQLLRST
GIRNLFVIRGDTVSPGQQFQNSAGLVQHLRKWQEQQPDHRQLTIAVGGYPYGHYQSSSQT
EELHYLQAKISQGADFLLTQTLYDAPSFLRYRDRCREAGITIPIIPGIYVPHSYRHLQAL
LNLTRIELGPTVRDAFEAHAHDAPDQFQAFMVEYFVGVVRELLQPNATTSSDPIKLVHFF
TFNKFQLLQQVLEKLDAFFK
>A0A3S1EGQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2C.T.Ca.TU.002.02.1.1|TrEMBL
MTALQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDELTETQVDMVK
TAH
>A0A142XGU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmata sp. SH-PL17|TrEMBL
MHIQDIFAQHRTTFSFEFFPPKTDEASEDLFRTIAALQSLQPSFVSVTYGAGGSTRDRTH
DLVVRIERDTNLTAVSHLTCVCHSLPEMTAILDRYAASGIENVLALSGDPPKNLANYDRA
KDAFHYAEELVKFLRTRPGANGRGFGIGVAGFPEGHPGCPNRLQELDNLKRKVDAGADYI
CTQLFFENRDFYDFRERCDLAGIKVPIVAGIMPITSKSGMIRMAELAAGAHFPAKLIRAV
GRCADDDAVARVGISWATEQCADLLHNNVRGIHFYTLNKSDATRQIYQNLGVESSAALRA
G
>A0A1F8MBX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_51_36|TrEMBL
MAPSFREVLKSGKFVITSEIGPPKGTNIEKMLHHIDLLKDKVDALNVTDHQSSVMRFPSI
GGCLAIKERGGEPILQVTCRDRNRLALQAELLFAYTRGVRNVLCLTGDAVVVGDHKAAKG
VFDLDSAQLLKTIRHMESGKDLGGNALDGTVEFCAGAIVTPEANPIEPQLMKFEKKIEAG
AEFFQTQAIYDLDKFARFMEYARQFPVKILAGIILLVSARMAKYMTDNVPGVIVPQNLID
ELVAAPKGEAINKGIEIAGRMIATIKKESMCDGVHVMAIGKEEVVPDILKAAGVVA
>A0A074WQ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium namibiae CBS 147.97|TrEMBL
MHISAKLQAAAKEKKSTYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDEALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDDPEELISHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDSAVRDVGTGLVVELCRKLLDNGILHLHFYTMNLAQSTRMILEELSITPSQEEP
LEKPLPWRQSLGLNRREENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFRDVAKLFANYMQGKVESLPWSESPITDEADALRLDLID
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
ARCYDATTPSRYVINDLMQEWYLVNIVNNDFREQRGIFPLFEGLEVPELDKEIKAPEVSQ
QTNGTTNGDKHGEEKKEEPKIANGDVTDTKIPDSVHKKLETQINGADEKPDTEPKDAPAH
NTGAGPSVDV
>A0A3A0ECJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MTKPSDPALSFEFFPPNTPEGAARLREVRARLAAFAPEFLSVTYGAGGATRDKTLATVLE
ILAEKHTVAPHLSCVGATRESVRELLALYRGHGIRRLVALRGDVPSGMREPGDFRHASDL
VAFVRAETADWFHLEVAAYPEMHPQARSPRDDLEAFAVKVRAGADSAITQYFFNADAYLR
FRDDARRIGIDVPIVPGIMPIANFTQLARFSDACGAEIPRWIRLRLASFGDDIEAIREFG
VEVVAAMCRRLLAEGVPGLHFYTLNQSAAAVRVLEAIGLARG
>A0A3D3SXF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MTISFEFFPPKSAETQAQLGLDSQKLAGLKPSYVSVTYGAGGSTRDGTRLTVEQMRAQFG
DVAPHVSCIGASRADIQGLLEDYKAMGIRRIVALRGDLPSGYGHGGEFMHAIDLVRFTRE
KFGDQFFIEVAAYPEFHPQARSADLDLHHFVEKMKAGANGAITQYFFNSDAYFRLVDEAY
AKGVDQPIVPGIMPITN
>A0A3S0EAS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MTTAPRLPISLEFFPPKTPEGVDKLAAVRQQLYPLGPEYCSVTYGAGGSTQDGTIQTVRA
ILSEGFDAAPHFSCIGASKASVREQLAQFKADGIKRLVALRGDLPSGYGGFGEFRYASEL
VAFIREETGPHFHIEVGAYPEMHPQARNPQADLQAYVAKVKAGADVALTQYFFNADAYFR
FVEDATKAGAAIPVIPGIMPITNSTQLMRFSDACGAEIPRWIRTRLEGYGDDKASIQAFG
LDVVSALCERLREGGVPGLHFYTMNQSGAVLAICQRLGL
>A0A1Q9PU85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalophilus pseudofirmus|TrEMBL
MTFIEKMKNEVLVGDGAMGTLLYEQGISKCFEELNLSDPNRIIDAHKQYIEAGAVIIQTN
TYAANRLKLEKYGLGEKVKIINQEAVKLAKEAGPNGIFIVGTVGGLQNFHQEEWTKEEVL
EALEEQIEALLASNVDGILLETFYDLDELLGAINIVRNQSELPIIANVSLGEIGVLHGGV
SLKEAIGKLENAGADVVGVNCRMGPSHMLRSLEDVPLPKRAYLSVYPNASLPEYQDGRLF
YHSNPEYFESMGEQFVNQGVRLLGGCCGTTPEHIRAFSQVAERRTPVEEKWVTPSLEKVT
KKIEFPRSLEPLSDIAKKRSSVIVELDPPKKLSTEKFIKGAKVLKEAGVDAVTLADNSLA
SPRIDNMALAAQIKEDVRPLVHVTCRDRNLIGLQSHLMGLHALGINDVLAVTGDPTKVGD
FPGATSVYDVTSFQLISLMKQLNEGISFSGKDLGQKANFSIAAACNPNVRHLDKAVQRME
KKIESGADFFMTQPMYSEEQIEAFYHETKHLDTPIYVGIMPLTSSRNAEFLHNEVPGIKL
TDSIRRSMASCETKDSAQLEGIKIAKSLIDTATQYFNGIYLITPFLRYEITAELTAYIEQ
KSTAKFV
>A0A8G2G3M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. JKS296|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLRDIATDYWNSGIRHIVALRGD
LPPGGGKPDMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A7Y0KN18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora sp. TBRC 11914|TrEMBL
MATVTERIQRGTPTFSVEFFPPKNDEGERTLWNTIRSLEPLDPAFVSVTYGAGGSSRDRT
VRTTGRIATDTTLTAMAHLTAVDASMEDLRHVIGSYAEAGISNVLAIRGDPPNDKDAEWV
PHPAGLQYTEELVHMVRRLGSFCVGVAAFPYLHPRSVDEDSDTRFFVSKVKAGAEFAITQ
MFYDADQFLRMRDRIHAAGCEIPIMPGLMPITTPKSAERGADFSGAPLPAAMSERLEPYA
DDADGFRQCGIDLCVELSQRMYDEGVGNIHYISMNRSPAVVDVVQRLGIAGASASN
>A0A3E0QZ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermobacillus sp|TrEMBL
MKPVLRDALRTAVLTGDGAMGTYLHQLGYPIGVSYEEFNMTRPETIASVHKQYYDAGARV
IETNTFSANAERLARYGLEDEAARINRAGVRIAREAVGADAYVVGAVGAIRTGRLTAVGT
PAIERAFAEQIDALLEAGVDGILLETFYDLEELLLALRLVRDRSDVTVICQLAAVGTGLL
YSGLPIGEAFRRLEDAGADAVGFNCESGPNGILHAIDALDGGVNLPISVFPNAGGADYVD
GRYTYAAGPAYFGDCARRFADRGARLIGGCCGTTPEHVAAIAASLAGWTPGAASERTAAT
GQASAPQTRESAPQIRVNAEPVPASGDEAPGGGDGPTIVELVRQRPTVIVELDPPRDLDI
SKFMAGARALRDAGADALTMADNSLAVTRMSNLALGALVKERVGIRPLVHIACRDRNLIG
TQSHMMGLHALGIDHVLAVTGDPAKFGDLPGSSSVYDMTSFDMIRMIKQLNEGIAFSGKP
LRQRARFVVGAAFNPNVKHLDKAVRRLEKKVESGADFIMTQPVYDAALIERIADATRHIG
VPIFLGVMPLASGRNAEFLHNEVPGIELSDEVRRRMAGLEGEAGRAEGVRIAEELLDAAL
ECFNGIYLMTPFMFYDMTAKLTGYVRAKAGVKTSVISCSSGENELK
>A0A550G506|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ALS1131|TrEMBL
MSNPCSSFIPYTLEVTGKGIHEVEQARAVIPAGTPINIAFLGNEDHAQRIHAAKVIRACG
AEPVPIISSRRLRSEEDRDELIGALVSQAAPKRFMFVGGDPATPAGPYQDSLALLASGVL
ERHGIDQVVITGYPEGHPKIDSGELMRALKWKLDFLREAGCAVEITTQFGFDAEAVVRWI
EQLRQQGIDTPVRIGVPGPADVGKLLRFARQFGVATSAAILRRYGLSMANLMQRVGAERY
WDQLQAGLGGRQLGRIGWHLYPFGGVEDGVTWINARLSADSRPQALPG
>A0A1F7T9H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Tectomicrobia bacterium RIFCSPLOWO2_12_FULL_69_37|TrEMBL
MSLVTESIRSPGLTASIELFPPKGEKAAGRVLREVEEIQAGMEVAFTSVTYGAGGSTQDG
TLELVLALAQRHPGRVVAHLTCVGAGEGDLGALLALYLKSGMRDILALRGDLPEGMTPEQ
AAAGGFRHAVDLVRYLRKLGGFASVGVACFPEGHPETPDLAAHLAHFAEKAEAGGDYAVS
QFFFEAHLWERFLEACERRRIGIPLAPGIMPVRDLEQLLRFAARCGATVPKSVVNALARY
KDDPEGFKERSADLAAGQVERLKALGVRHVHIYSLNKSDIILKIADRLGWRKKAPAK
>A0A2S6RGA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha9_Bin1|TrEMBL
MGLGIKNKNISLEIYPFMKGGNNDKLCKNLKVFEKFKPKFVSVTYGASGSIQNNTVSLLT
KISQNTCLNLAAHLTCVNSSKIFIHKILSYYWNNNIKNIVALGGDLPKISIKSEYNHAYE
LIKDIKKNNTFNISVAFHPEGHPDDKNIMKEIEYLRLKFDCGASQAISQFFFNIEYFLKF
RDLINKKQSNIKLIPGIILISNFEMIERFARKCRTDIPESEKKIFSSIKDKTNIPVKVTV
EYAYNLCLRLKSEGVQDFHIYTLNKLDTSLKLINELQ
>A0A5E8AHH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas aurantiaca|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGISFEFFPPKTEKMETQLWEAIRTLEPLAPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGDPNADIDNL
KRKLDAGASRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPSETVAAA
>A0A1I7CFP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas saccharevitans|TrEMBL
MSTLEHPLGISFEFFPPNTDAGREKLVGVRDALAGRAPRFFSVTYGAGGSTQARTLNTVN
MVRESGFTTAPHLSCIGSDKGELRELLTRYREDGIDSLVALRGDLPSGMGGGGVGQLRYA
NELVEFIREETGDHFEIAVAAYPESHPQAPNFERDLANFARKMQAGANLAITQYFFTAEA
YFHFVERARALGVEAPIVPGIMPITNYAKLARFSDACGAEIPRWIRKQLEAYGDDSEAIA
AFGEEVISRLCQRLLDGGAPGLHFYTLNQATPCLRILDNITG
>A0A1C5GWB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora halophytica|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTHEGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGDPGGEWVRHPEGVLYAEELVRLVRDAGDFSVGVAAFPYKHPRSPDIASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAATGCDTPILAGVMPVTQMGTIERSVQLSGAPF
PPALAERFARVAHDPEAVRRLGVEQASEMCAKLLDEGVPGIHFITLNRSTATREVWRSLQ
AGARV
>A0A372BYF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenzhouxiangella sp. 15181|TrEMBL
MATTTEYPQLSFEFFPPKNDKQQETFERSRDQLAELGPDYMSVTFGAGGSTRTRTFETVR
NIIEATGVPAAPHISCMSEDIDSIRDLLDDYRDNGIDRLVVLRGDRPSGGGTGVFDHAVD
LVRFIREYYGDRFHIEVACYPEHHPESKTPEADMKHFRAKVDAGADGAITQYFFSAESYF
RFVEDVRSRGVDVPIVPGIMPITNYSGLARFSRMCGAEIPLWIAKRIEAWEEAEDMTSLR
AFGEEVITDLCRRLLEGGAPGIHFYTLNRWKASTALCRNLGLGKGNEAKRNIA
>I4HS37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa PCC 9809|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFDRLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A4R6SZC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter metabolipauper|TrEMBL
MKIIDHINNAKGNTLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKDETENALIDMQFLGIDN
VLVLRGDARKSDNAFIPTPDGHAYASDLLNQVTDMNKGKYLHDDMGTSERTDFCIGVAGY
PEKHFESPNLDTDFKYLKLKVDLGAEFIVTQMFFDNKKYKEFVDKCRANGINVPIIPGLK
PITNSKQLMSLPKVFHLDIPIELSEAIQSCSNEKDVKSVGIEWMINQCKELKEMGAPVLH
FYTMGNPEPTKKIIQGVF
>A0A3D9AUL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. 5_R23647|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICSAIQHKYGVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTLGGHASAMDLVNQINNLGRGKYLHDDEQICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVTKAREMGITVPIIPGI
KPIATKNHLKLLPQVFKIDLPEDLINAVEGAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELL
>A0A1M7IL29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptosporangium aurantiacum|TrEMBL
MATGLVPPKVGRIPKVGRVPKVRRISVGDLVRDDAPTFSFEFFPPKTDAGERQLWQAIRE
LEALQPSFVSITYGAGGSSRDRTVSITERIASETTLLPMAHLTAVNHSVAELRNVIGNYA
AVGVHDVLVLRGDPPGDPQAEWLAHPEGYSYASELVKLVKDSGDFCVGVAAFPEKHPRSP
DFESDVQFFVEKCRAGADFAITQFFFDWQDWARLRDASVASGCDVPIVPGVMPVTNVSQI
ERMAILSGAAFPVDLAERLRAVADDPVAVRAIGVEVATALSSRLLAEGAPGIHFITLNRS
AATREVWANLAPAKVAAR
>L0DST2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioalkalivibrio nitratireducens (strain DSM 14787 / UNIQEM 213 / ALEN2)|TrEMBL
MNHTPNTRPAFSFEFFPPKNPEGTERLRRARARLTALDPAYFSVTFGAGGSTRDRTLETV
LEIQSEGAVAAAPHISCISSSRAQLLDLLTTYRDHGVRRLVALRGDLPSGTGVGGGLGEF
RYAAELVAFIREQFGDHFTIEVAAYPEFHPEATNAEKDLEHFRKKVAAGADAAITQYFYN
PDAYVAFVDRVRAMGMDIPIVPGIMPITNYTQLARFSDACGAEIPRYIRKRLEAYGDDSA
SIRVFGIEVVTRLCQRLLDDGAPGLHFYSMNQAGPSEAIWNNLGLAQPR
>A0A2R3JS07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus sp. CBA3605|TrEMBL
MNLRQALKQRVLVADGAMGTLLYGNYGLSSAFENLNLTHPDTILRVHQAYINAGADVIQT
NTYAANRLKLTRYDLQDQVVAINQAAVKLAVTAQQAADHPVYLLGTLGGLAGDTDQTVQQ
ATPAAITASLTEQLNALLATKALDGILLETYYDLPELLTALKIVTAHTTLPVITNVSMLA
PGVLRDGTTFADAVIQLAAAGAAVVGTNCRLGPYYLAQSFENLPIPANVQLAVYPNSGLP
GTNQAGQVVYDGEPSYFEEYAERFRQLGLNLIGGCCGTTPLHTAALVRGLVSRTIVPHSN
QSVPPIATPLTPTVGHHPFLKKVAQQKTVLVELDPPKDFATARFFKGAQRLKAAGVDGIT
LSDNSLASVRIANTMIAAQLKLNYGITPIVHLTTRDQNLIGLQSEIMGLHSLGIEDILAV
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGNSLKQATDFRVAGAFNPNAFR
TNVSTKSIERKMAYGCDYLITQPVFDLEKVHDLAVALQASHLNIPVFIGVMPLVSKRNAE
FLHHEVHGIRLPTSVRERMAQAELAGNEAAVGLQIAKELIDGICTEFNGVHLVTPFNRFK
TIIKLVNYVQQKNLTVTK
>A0A0A0BMA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas bogoriensis 69B4 = DSM 16987|TrEMBL
MTTTAPAPLPLLDVCPKRMQVGPCGGVAADGGCEVRPAQRCTFLGGQPHEGVELPARRVP
GEVGVQRGSGRFEAGLAAGRFMVVTEVNGADSADASEFTAAAVRLAQVADVVSITDHSGA
NVHMGNVAATAHLLAAGVETMPTFTCRDRNRMALQGDLLGVSSLGAQNVLLVSGNHVDVG
DSPDAAPVFDLDSTRLIGVAARLRDEGVLDNGRRVDVAPSYLIAAAAHPFAPPYERRAEQ
VVRKVRAGADVLITQHVFDLPLWRSFLADVQAARPDAPPFHLLAGVAVLPDEATARRVNA
GLRGFSIPEATLDRLRRSPDPAREGVRIAAETVQEMRASGGVSGVLLAPVTGRTNALAAS
DEQVDIVSAVLQEAGMPVTAAARAGVAS
>A0A2S3UKB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium marinum|TrEMBL
MSESSSRRSHQAAPSPITASFEFFPPKSEKMAETLWSTVQRLAPLNPSFVSVTYGAGGST
RERTHKTVDRILKETDLAPAAHLTCVGASREEVDAVVRDYWSLGVRHLVALRGDPLAGIG
TRYVAHEKGYAYASDLVAGIKKIANFDISVSGYPEKHPESGNWQSEIDNLKRKVDAGADR
IITQYFFDNDLFDVYLDRIAAAGINIPVIPGIVPIHNFEQTMVFSAKCGTSIPQWLARRF
SGLANDPETRKLVGVAVACEQVMDLVDRGIYDFHFYTMNRADLTYAICHMLGMGKPAHEE
MAA
>A0A3Q8GQS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurellaceae bacterium 12591|TrEMBL
MSYAKEIDTLNQHIADLNGKINVSFEFFPPKNEKMESILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLEAAPHLTGIDATPEELIEIAKDYWNSGIRRIVALRGDEP
KGYAKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLVKMAAITNVKIPAWLAKNYEGL
DDDPTTRNLVAASVAMDMVRVLSREGVNDFHFYTLNRSELTYAICHTLGIRPSSE
>A0A3P6H8P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica oleracea|TrEMBL
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNAICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAYGIHFATEMCKKILAHGITTLHIYTLNVDKSAIGILMNL
GLIDESKITRSLPWRPPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYSTLSDYQFMRPRARDKKLQQEWVVPLKGIEDVQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TLVEKSKAFPSITFMAVNKAENWVSNIGESDVNAVTWGVFPAKEVNQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNDYINGDIFSVFA
>A0A2M9EU28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium NML07-0707|TrEMBL
MLPISFEIYPPKNDDQRAQLDRTLEKLKAYQPQFISCTYGAGGSTREHTAETVQLLGSKH
GLEGVPHLTCIGSTRQEIIQLLTHYQQQGVRRIIALRGDMPSGMLDPGELRHASDLVTLI
RESFGQHFHIEVAAYPETHPQARDALADIENFRRKVDAGADSAITQYFYNADAYFRFVDD
VRARGVEVPVVPGIMPISNFSQLQRFSESCGAEIPRWVVQRMRAFGDDSGAIREFAADLV
AALCQRLIHGGVPGLHFYTLNLARPVGNILKRLQ
>M3AX30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudocercospora fijiensis (strain CIRAD86)|TrEMBL
MDKLTDKIAALPPGANYCSLEFFPPKTQQGFSNLNARLSRMAHSLRPLFVNVTWGAGGST
SAKSLALAELTQRELGLTTCLHLTCTNMSRKLIDEALAQAKVLGIRNILALRGDPPRSEE
YRDDNDADAAEDDSNKDFTWAVDLVRYIRKQYGDYFCVGVAGYPEGHSDQSHPQHQSVEH
DLPYLVEKTKAGADFIMTQLFYDVDAYEKYENTLREHESGVFKTIPIIPGLMPVQSYQIL
RRTAKLSHAAIPSDVSARFEAVKRDDEAVKKVGVDVISEIVEKMKGIGNLPRARGFHFYT
LNLEKVVAQILERCNLIPPSTPEVISHGSSGDDHAVAVEESDDFVLVENAKKRDHRRKSS
MVNSQPRNRIIVSHTRASSTSSNRASSTSAFEARDDEAGVPKEKINSRANTLAISEGEGA
LGREATWDDFPNGRWGDARSPAYGQIDGYGVSLHVSAPDAKRLWGEPMKPEDVSMSFRRH
LEGEIDSMPWSEESLQPETLTIKNELLQLINKGWWTVASQPAVNGVRSTDPVFGWGPKNG
FVFQKPFVEFFIPAAEWKKLQFKLEEHPQITFFAGNAQGDFVSSDEDSVNPVTWGTFTGK
EIITPTIIEAVSFKAWCEEAFGIWAEWQRIYKPGSESSKLLERIRKDYWLVSVIHHGFLE
KGALWNDLLEG
>A0A660Z255|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium|TrEMBL
MRVIDHLMNAKEPLISFELIPPKRGGDIKDVLAVLDELIKYKPPFIDITSHSAEVIYDET
ADGIKKKVKRKRPGTLGICALIQNKYNVDAVPHILVKGFTREETEDFLIELNYLAIDNVL
AVRGDDSGYKKPVPLGKSISEHSLDLVKQIVDMNKGKYLEENLLDAKATNFCVGVGGYPE
KHFEAPNLKSDVRYAKQKADAGADYLVTQMFYDNKYYFDYVKLCREAGIDIPIIPGLKIL
TSKSQLHSIPKNFHVSIPTELADEVEAAKPDDVLKIGVEWSVNQVKQLLDENVPSVHFYI
MLDSKPISMLLDQLKIFKKTA
>E1Y8Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MAFQPRRRTQKISKRGPFYMKSESLSNLQSILDKGEFAVTSECGPPRGADPEIIRKKGEL
LKGYVDAVNVTDNQTAIVRMSSIAACAHLVQLGMEPVMQMVTRDRNRIALQSDILGAYSL
GIRNILCLSGDHQTFGSQPDAMNVFDIDSMNLVNMVKVMKTEGKDMSGFDLKNAPEMFIG
AAANPFADPFEYRVIRLAKKIDAGADFIQTQCVYNLDRFKEWMRLAREEGLTEKTHILAG
VTPLKSERMAKYMATKVAGMDVPESLIKRMGGVPKEKAAEEGIRICVETIAGLREIKGVH
GIHIMAIEWEEKVGPIVEAAGLSPRPQAA
>A0A3A0B653|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium|TrEMBL
MKVTEHLENSTRPLISFEIIPLPRGGDIRQVFEIIDELIKFEPPFIDVTSHSAEVHYEET
ASGIRKKVKRKKPGTIGISVAIKNKYNIDTVPHLLCTGFTKEETEDALIELNYLGIENVL
AIRGDDNGYIKPLTDGRTSNRYAIELVDQISKMNQGIYLDTELLNASPTNFCIGVGGYPE
KHFESPNLSFDVEYAKKKVEAGAEYIVTQMFFDNKYYFDYVRRCRDAGITVPIIPGLKIL
FTQKHLTNIPKNFFVNIPEELSGEILKSKSEHAMEIGINWTLKQCEELLNNNVSSIHFYI
MHNIKPVKKLMDKLKL
>A0A435NL32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.15.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A858SSG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseobacter ponti|TrEMBL
MSTPAVSFEVFPPRSIDASFRLWETAQALAPLAPRFFSVTYGAGGTTRDLTHDAAYTLRK
SSGLPVAAHLTCVGATRDETMATARRFAKAGVTDLVALRGDAPEGSDGFTAHPDGFANSV
DLIEALAATNLFTLRVGAYPEKHPEAASQAASIDWLKAKIDAGAAEAITQFFFEAETFLR
FRDDCAKAGITAPITPGILPVTNWASARKFALRCGTSVPLWLDQAFETAIRDNRHDLLAR
AVCTEMCSALVDEGVENLHFYTLNRPELTREICHALGVTQAETGVRDVA
>A0A804P6R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zea mays|TrEMBL
MCMLLRKDSGHYLAIVVYVKCCSLEEERRKERIPTELMRSFILTSHTAPGRAPAASSICN
DRTRRRAVCVETMMHLTCTNMPVEKIDHALETIKFNGIHNVLALRGDPPHGQDKFVQVEG
GFACALDLVQHIRSKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLKRKVDAG
ADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFMRMTGFCKTKIPSEIT
AALDPIKDNEEAVRAYGIHLGTEMCKKIIASGIKTLHLYTLNVDKSALGILMFTRPRGRG
KKLQEEWAVPLKSVEGISERFTNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFL
TINSEPAVNGEKSDSPTVDHLEMSRPFLIHLSAGQSDSPAGHSQQKTRELPE
>A0A7W9G9L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea jabiensis|TrEMBL
MALGRPSILPDRVPTVRDMLAAGGRSFSFEFFPPKTDEGERQLWKAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERIAHDTTLTPVAHFTAVNHSIRELRHLVGRFADAGVRNILAVR
GDPPGDPTAEWVQHPEGVLYAEELVRLIRQSGDFCVGVAAFPYKHPRSPSIEADTEFFVR
KCEAGADYAITQMFFRADDYLRLRDRVAARGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PAEVAARFEEVADDPAAVRRLGIEHGAELCRRLLDEGAPGIHFITFNRSSASREVFERLD
AVPLSA
>A0Z2Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine gamma proteobacterium HTCC2080|TrEMBL
MATEGSCSLEFFPPKTIPGREKLLNETLPALADLDPEYCSITYGAGGSTRDTTVATVSAV
AEAGQDVAPHLSFGTDNRETLKNLLEQYQQQGVQRLVALRGDAPAGNASQNSSCIYASEL
VSFIRETTGDHFNIKVAAYPEIHPEAVSYGHDIHFLKAKLDAGANAAVTQYFFNVESYFY
FMDRCAAAGITQPIHPGIMPITNFANLMRFSTACGAEIPRWIRQRMSDFSDDPDSAHKFG
IEVVSQLCSTLIDSGAPPIHFYTMNQAEPMRTIARNIGLLKGGNNDAGDQALHQAVA
>A0A7I4Y547|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemonchus contortus|TrEMBL
MVNAIEPNTISNGANTNGSLKKIDSLTAIPYVGSNPSLHERSGSDDEHLTFEVGRRRYIP
LHERINRRVQDKTPFFSLEFFPPKTANGVANFFTRLDRFNEGGPLFVDITWHLASDPANM
NRETSSSSIAAGCLDYCRVDTMLHMTCAQYSKEQTIKHLEQSKSVGLRNILALRGDLPHM
DTDGVPIYKYRALDMIRWIREEFGDYFTICCSGYPAGHPESPSYKADLLYLKSKCEAGAQ
FIITQLFFEAEVFEEFVRDCREIGITVPIIPGIMPIMGYDSIRRIATLSQLTIPESILSD
LEPIKHDDDAVMKYGTVKAIEMCRRILSNGSAPSIHLYTMNREGACREILQELGLWHKRP
MRALPWDPLGSNHPLRCKEDVRPIFWSARPKSYIYRTRDWDDFPNGRWGNSSSPAFGDLQ
DYYLFHLKAQTKKEDLLKMYGEEINSFDDVKKVFVNFISQGPNDRGVKVTSLPWNEQESG
VQAETKLINEQLLWCNQNGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFISK
ENAKSLLEIVDDYYPRVNYHLINHDGSFDRMNGEQTTPIAVTWGVFPGAEIAQPTVVDPL
AFRAWKDEAYDAWIKNWANIYPKDSVSRKIIQKIHDEFYLLNLVDNDFQKPVIIYEVLEK
MIKRTKETTNPTT
>A0A7Y2NHF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MSAPRISFEFFPPHSLDGSFRLWDTVQTLAPLGPDFVSVTYGAGGTTRDLTHDAVKTIGA
HYDLNVAAHLTCVNASRAETLAIAESYAVAGVREIVALRGDPPKGAGTFAPHPDGFADSA
ELVAALAETGKFHIRVGAYPDPHPDAADPTADVTWLKRKIDAGAGSAITQFFFEAETFFR
FRDACAAAGIDAPIIPGILPIENWAGVKKFAARCGTQVPQWLADAFETATRDDRADLLAT
AVCTELCSDLMDGGVENLHFYTLNKPGLTRDVVHALGITPEVTLEKVA
>A0A1D6L977|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zea mays|TrEMBL
MKVIEKILEAAGDGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIGILMNL
GLIEESKVSRPLPWRPATNVFRVKEDVRPIFWANRPKSYLKRTLGWDQYPHGRWGDSRNP
SYGALTDHQFTRPRGRGKKLQEEWAVPLKSVEDISERFTNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVNINQKGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDG
ETFSNISPNAVNAVTWGVFPGKEIIQPTVVDHASFMVWKDEAFEIWTRGWGCMFPEGDSS
RELLEKVQKTYYLVSLVDNDYVQGDLFAAFKI
>A0A5C2SKE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentinus tigrinus ALCF2SS1-6|TrEMBL
MKISQKIEQAAKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
ELTSELVKTCQKLIGIETCMHLTCTGMPKEKVDIALREAKQHGCRNVLALRGDPPVGKEW
EAVEGGFHYGIDLVRYIRKQYDDYFDIAVAGYPQTHLLPPEEAALEMQYLKDKVDAGANF
IFTQMFYDIDMFVDWVRAVRAAGITIPIVPGIMPIQTWNGFQKATSLAKITVPQAFLDEL
EPHKNNDEKVRELGTKLVANMCRQVLAADLGIKGLHFYTMNLEKGCRMLLEELNLVPRVE
VVKPLPWRQSLTPNRRAETIRPIFWANRTRSYLSRTENWDEYPNGRFGDSRSPAYGELDG
YGIWLKQSKDDALKLWNTPTTVDEITALFAKFCLGQLQALPWSDSAPSSETTVIAQQLAK
LNSLGFLTINSQPAVDGARSDDRIHGWGPANGYVYQKAYLEFFVSPELLDMLIPHIERDI
NITYYVINNRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGRQW
AKLYDPDSPTRKLIDGIMDSYYLVNVVHNDFKKPEAIFEPFFKAGAEYAAKHDAPKTNGH
AH
>J2TD08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM67|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VQFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1R3MQ97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zea mays|TrEMBL
MKVIEKILEAAGDGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIGILMNL
GLIEESKVSRPLPWRPATNVFRVKEDVRPIFWANRPKSYLKRTLGWDQYPHGRWGDSRNP
SYGALTDHQFTRPRGRGKKLQEEWAVPLKSVEDISERFTNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVNINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLD
QLIEKIKAFPSLTYIAVNKDGETFSNISPNAVNAVTWGVFPGKEIIQPTVVDHASFMVWK
DEAFEIWTRGWGCMFPEGDSSRELLEKVQKTYYLVSLVDNDYVQGDLFAAFKI
>A0A1K1S7K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. NFACC16-2|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VEFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A5Q4DM94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MSTPRVSFEFFPPKSLEASFRLWDTVRMLAPLAPGFVSVTYGAGGTTRALTHEAVTTIGA
QFGLNVAAHLTCVDATRAETLAIAESYAQAGVTEIVALRGDPPKGQGGFAPHPEGFAHSV
ELIEALAATGNFKLRVGAYPEPHPDAADDLADVRWLKRKFEAGADSAITQFFFEAETFLR
FRDTCAREGITGRIIPGIIPIGNWQGIRKFALATGASVPAWLDEAFEKAARDGREDLLAT
ALCTELCDTLVREGVEDLHFYTLNSPHLTRDVCHALGVVPQVALENVA
>A0A2E8Q725|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
TARRLAEDGFPIMPHFPARIISNKAMLNDWIKRYQSEAGVDQALLLAGGVSKPHGEYKSS
MDLLETGLFDKANFKNIHIAGHPEGNKDIDPDGSRKNVDAALKWKQNFKNKTNAEMAIAT
QFAFEAGPIIEWANSIKSAGIDIPIHIGIAGPAKLQTLIKFAIACGVGPSLKVLQKRATD
VTKLLLPYEPIEVLSQLANYKANNPEFNISSVHFFPLGGIKTNAKWVTENGGTSGIPANQ
V
>A0A2N6CXG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sedimenticola selenatireducens|TrEMBL
MHSQQTDQKLFSFELFPPKTEEGMEKLKTQVKKLARINPLYVSVTFGAGGSTQHRTFQSV
EWLVSEGIEAAPHISCISSSAAEIVEMLNRYKNQGIHRLVTLRGDLPSGTGLSGRGELNY
ANELVTLIRREFGYYFHIEVAAYPEFHPQAANARADLNNFKRKVDAGANAAITQYFYNAD
AYFRFVDSCEKMAIGIPIVPGIMPITNFSSLSRFSDACGAEIPRWIRKRLEAYADDVESI
RAFGVDVVSELCRRLLDHGAPGLHFYTMNQSAATLKIWDNLGLTE
>A0A329WYK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus bodei|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSINRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGD
LPDNSEKPKMYGADLVELLKKEADFDISVAAYPEVHPEAKNSQADLISLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQLRRFATMTNVRIPSWMTRMFE
GLDDDPESSNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A2Z5ZLP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter orientalis|TrEMBL
MTGILSNWLSEMHIDGLLSRNSEAPILSFEFVPPRTDAMEQRLWHCIRHLAPLAPRFVSV
TYGAGGTTQTGTLSTVLRLKRETDLIPAAHLTCVGATREEVDGLARCYRDAGVNHIVALR
GDPCAGYSPRPGGYAYASDLVAGLRRIADFDISVVAYPETHPTASSPDADLDNLKRKLDV
GATRAITQYFFDSEIYLRFLDRCLAAGITAPIIPGIMPVSNYEQIVRFSAVCGVTVPAWL
RHLFDGTAKNPELRRIIACMVAVEQIRTLQTYGLNEFHVSTLNRSDLTYAIAHVLGVRPT
ETNASHNLTGLLETTEIPHDRETPADFDPTEGTQEGAPPFMLRTLFG
>A0A840LF38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paucibacter oligotrophus|TrEMBL
MSTNKKTPVSFEFFPPNTPVGTEKLKTVVQDLSVLNPHYFSVTYGAGGSTREKTLATVMD
IAASGYEAAPHLSCVGSTRENIAEILATYRAQNIRRVVALRGDLPSGTATAGEFRYASEL
VSFIRETQGPDWQIEVAAYPEYHPQQRYAAKDLQHFAAKMKAGANAAITQFFFNPDAYFN
FVDEVRKLGVSAPIVPGIMPFHNYARIAQFAARDGIEIPRWIALKMEGFMDDAASIRAFG
LDVMTRVCERLIEGGAPGIHFYTLNQSGLTLELCKRLKLG
>A0A2R5EKZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus agaridevorans|TrEMBL
MSGALAAKLSLREALAERILTGDGAIGTYLYQMGFPVGVSYEEFNVLKPDVIENVHRQYY
EAGARVIETNTFSANSVKLSKYGLESEMEAINRAGVRIARAAVGPDAYVVGAIGSIRDGK
LKNLRTSLVADAYEQQMKALLEEGVDGLLLETFYDLAEMKLAMSIARKLTDIAVICQFAV
EDVGRTLDGVALSDAFRELKEMGADVIGFNCRSGPNGIMRAIDSIGERPEDVPMSVYPNA
GIPDYVDGKYAYSAGPEYFAESAKRFADRGARIIGGCCGTTPEHVAAMAAALAGYVPAAP
GANQAESTSITVTETLAGGTGEGDRDETPNIVDLVKQRHTVIVELDPPRDLDISKFMTGA
AALKEIKADAITMADNSLAVTRMSNLALAALLKERVDIRPLVHIACRDRNLIGTQSHMMG
LDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNDGIAFSGKPLKQRAKF
VVGAAFNPNVKHLDKAVQRLERKIASGADYIMTQPVYDPELIVRIAESTKHLDVPVFIGI
MPLANGRNAEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAEGVRIAKELLDAALPHFNGIY
LITPFMFYDMAVQLTEYVWQNTKQLS
>C2S8Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus BDRD-ST26|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKETAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A4Q8U5N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mediterraneibacter sp. gm002|TrEMBL
MKIIDKLNEDRIHISFEVFPPKTDAGFEKVKDATDKIAQLNPSYISVTYGAGGGTSKNTA
KIASHIKHELGVESLAHLTCASSTKEEVRQVIENLKELEIENILALRGDIVPGMTFPSED
RFHYAYELVEEIKKHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITTAAQMKRSQELSGTVFPRRFLALLDRFGDYPD
AMKQAGIAYATDQIIDLLANGVKNIHVYSMNKPEVAAKIIENLSEVIKC
>A0A373TIB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF23-6LB|TrEMBL
MKLKEYIQTKRIIADGAFGTYYISLYGDGSRAENGAGLSNLPELANIKAPERVIGIHTEY
IEAGAQFVRTNTFASNTKSLSADMEKVKENIRAAVMCAKMAAGKVDREIYLAGDIGPIPV
EGMLHSDRLTQEYIAIGETLLSQGIDILLFETFPELETILPAVTYLKENHDCTILVHFSV
NQFGYSNTGLSAKRLIAEANACPYIDGTGLNCGVGPGHMEKLIRKIAPDDTTFLSVFPNS
GYPKYLNNRLTFTDNAEYFTEKMEEIAALDVGIFGGCCGTTPEYIRRIAAGISADHPVRK
TETEAEKITVSEHPVYGFMERRVKEPAHKLIAVELVPPLNANDEKLLDAAHILKNAEVDV
VTFPDSPSGRTRADSVLMAEKIRLETGLCVMPHICCRDKNAIAIRSTILGSSLNHITNFL
LLTGDPVPVLFRQTTKSVFNFDSVGMMKIVQEMNSDTFTDHPVTYGGAINHNRMNTKAET
ERIRRKMAAGATFFMTQPIFSAEQADVIRQMKKETGATILVGLMPLVSRKNAVFMKNEMT
GIEIPDTVIERYREDMSREEGEACGVQIAREFMAMTDDFADGYYFSFPFNRVHMLKKILK
>A0A1V5J240|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium ADurb.BinA014|TrEMBL
MGTEIKKMGIEPLVHLTCKDKNRSSIESQLYALDRAGVRNLLVMTGDYPVSGYMGRPSPV
FDLDPIHVLQLISEMNKGLEYPGPKGIIRQQKCDFFAGAVVSPFKATEAEQMAQYYKLKK
KIEAGAQFIVTQLGYDARKIHETFLFMKQSGFNVPIVGNIYILPYGAANKMNRNGLPGNV
VTDKLLADIDQERNNSDKGVQARILRAARMYAIIKGIGFNGVHIGGHNIKYEQVEEIIRQ
GEALAPQWTELIKYFDYPMKNGFYYFEFDPKTGLNKEKPIDPQTVETAGKPEIFYGISRF
FHMLMFEPGKKLYGIMKAISGKIAGSKLENIFHKLEYLTKVLIFNCRDCGDCALIDVAYL
CPMSQCPKNQRNGACGGSYQGWCEVYPFKKQCIYVRAYARLKKYAQEKQLEQNIVPPCNW
DLHQSSSWLNFYLGKDHNAKKQDNSPAGK
>A0A844SPH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium pachyrhizi|TrEMBL
MTETISSVPNAPRAPKAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTITRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAGIKRRHADIEISVSAYPEKHPEAKDFDADIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A8E1XPJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. zg-578|TrEMBL
MVTGPGRSLAEMIREGGKSFSFEFFPPKDEAGEQQLWDAIRALEPYRPTFVSVTYGAGGS
TRDSTVRITGRIARDTSLIPMAHLTCVGHTREELERILDSYREAGVHHVMALRGDPADGP
RAAWTPTEGGLTYATELVELVRSRGDFRVGVAAFPEGHPTAESLDHDADVLVAKARAGAE
FAVTQMFFRAADYFGLVERVRDRGVDMPILPGIMPILNLAAIRRQGELIGADVPQEIVSR
IAAHTGDPVRVRAEGIAVAAELCEELLAGGAPGLHFYTLNRSRATLEIFDRLNVSS
>A0A1H2QG38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga granulosa|TrEMBL
MKVTEHIAQAKGKTLFSFEIVPPKKGNNIEELYKNIEPLLEFKPPFIDVTTSREEYLYKE
HPNGLLEKKLIRMRPGTVGICSAIQHKYNIDTVPHVLCGGFTKEETEDLLVDCFYLGIDN
IMALRGDAMKEERYFRPTKNGNVYALDLVKQIDNLRKGIYLHDTLETNIGMDFCIGVAGY
PEKHIEAPSKTFDLEKLKEKVDNGADYVVTQMFFDNKKYFEFVAKAREMGIHVPIIPGIK
PVSVKKHLNILPQAFFLDFPEQLVKEIEKCKNNEAVKQVGIEWAIAQSIELKKAGVPSLH
YYSMGKSENIIQIISQVF
>W0RGU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatirosa kalamazoonesis|TrEMBL
MTASPPDRQAAVQRLLDPAEIVLFDGAMGTELYARGIFINQCYDELCLRAPDLVRDVHHT
YAAAGAEVLETNSFGANRAKLVAYGLETQVEAINRRAAELAREAADAARPVSGRRQHPVL
VAGAVGPLGVRIEPYGPTSRDEAREMFREQLAALRAGGCDVFLFETFVDLLELEQAIAAA
RDVDATVPVIAHVTVGTDLRTPYGASPEDAARALDHWGADIVGLNCSVGPQAILEGIERM
AGVTRRKLSAMPNAGMPREVGGRRIYMASAEYFATYARHLVQAGAKVVGGCCGTTPDHIK
AMCSALRVERAMVHVESGLGTRDSGLVNDNRVPSPESRVPRAKEPVPFADRSRFSGKIAR
GEFVTSVEIVPPRGVDTAKLLRDAATLHAAGVDAINVPDGPRAQSRMGAIATSLLLEQQV
GIESVTHYACRDRNLLGMLSDLLGASALGLRNLLLITGDPPKMGPYPDATAVFDIDAIGL
TNLVRNLNRGLDPGMNEIGAPTRFAIGVGVNPAAIDPAHERQRFAWKVEAGAEYAITQPV
FDAAQLERFLRTIEDVRIPVIAGIWPLVSARNAEFLANEVPGVTVPDAVLKRMRAANERS
KEHAVAEGIAIAREMLEAVRPEVQGVQVSAPFGKVELALDVFEDVTAPRAAGADVAASY
>A0A354EA56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia sp|TrEMBL
MHLRERLQSGAGPSLSFEFFPPKNEQAASALYQTIRELEPYRPSFVSVTYGAGGSTRELT
REVVLRIQHESRIPTVPHLTCVGHSREEVWNILDQYARAGVRAVLALRGDPPRGAEDYNR
DADAFRHAADLVAFIRGYNESGRHPDPEGFAIGVAGFPEGHPATPNRLREMDFLKAKVDA
GADYICTQLFFDNHSFLDYRERCLLAGIKVPILAGIMPVTSLSGMNRMAELSGGTCFPAR
LLKALKRAGSNPDAIQEVGIQYASSQCAELLDSDVDGIHFYTLNQSRATREIYRNLGLKD
SLQLLEHGEDK
>A0A1W9MS49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium IS3|TrEMBL
MELKSGSNLEKVLKAGHFAFTGELGPPRGADAHEVKHKAAFLKGNVDSVNITDNQTAMVR
MASWAACLILIQEGLEPNFQMVCRDRNRLAMQADILGAYAHGIRNMLCLSGDHPKFGDHP
TSMGVFDIDSMQLIQMVKKMRDEGKFLGGADLHGAPKMFIGAAENPFAEPCDFRVHRLAK
KVAAGADFIQTQCIYNMPKFREWIRQSVDMGLTEKCYILAGVTPMKNVGMANYMKNKVPG
MDVPDEIIKRLKGVPKDQASEEGIKIALEQIEEFKTMKGVAGVHLMAIEWEHKVPEIAER
AKVLPRPVV
>A0A2U3JVV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacter sp. SbD1|TrEMBL
MKAGTNLEKVLESKRFAVTAEVGPPKGAGTSGVLKKGEKLKEFTDAINVTDNQTAIVRMC
SLAGCTLLKRVGVDPVLQMVVRDRNRIAIQSDILGAVALGIGNILCLSGDYQSFGNHPTA
KGVYDLDSVQLINTLKKMRDERKFICGEAIAGELPLFIGAVENPFADPFEYRVFRLARKV
KAGVDFIQTQAVFDVARFEKWMKLIKDHGLEEQVHILAGIIPVKSAGMARYMRDYVSGVT
VPDEVVTRLEQATDVKEEGLKISLEIIEQIMEIPQVHGIHIMAVGWEEIVPVIVEQAGLL
PRPEV
>A0A2X0R7U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSEEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHRS
>A0A2S3VJU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas laurylsulfativorans|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1I1SW05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klenkia taihuensis|TrEMBL
MTGTVRELLEKGQPTWSFEFFPPRSPAGEAQLWTALRELERLAPSFVSVTYGAGGSTREG
TLAVTERIATDTTMLPLAHLTAVDHSVDELRNVVARLAAAGVTNIMALRGDPPGADPQAD
WTAHPQGLSYAAELVELVRGMGEFCVGVAAFPETHPRSPDAETDADMFVAKCRAGADFAI
TQMFFRVEDYLRLRDRVAARGCDVPLLAGVMPVTSAKQIARIVQLSGQAFPAELAERFAA
AADAPADEQRALGVDVATQLCEQLLAEGVPGIHFITMNRSTATREVYERLSPVSAASAS
>A0A2G7H302|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus sp. UR1|TrEMBL
MTRVSVELVPRSRSGLRAEITQVVAALPGVDTVNIPDLTRYSLRSWLGCAFARPAYRAVP
HLRAVDFNPREPLPFLGTLDQHDITEVLVVTGDAPADMSARVYDQDAVDLIRRLRREAPH
LTVYAGLDPYRQSFARERDYLERKLDAGAAGFFTQPFFDLRVMDAYSDLIPEGTQVWWGA
TSILTESSLNYWRARNHAVFPRSFAPTLECNRAFAADLLTFARERGQHAYFMPVKVDVQA
YLEGIL
>A0A5J5IQI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ginsengibacter hankyongi|TrEMBL
MKVTDHIKEAKDTVVSFEILPPLKGKTIESIYNHLDPLMEFDPAFINVTYHRSEQVFKKK
ADGTFEKVEVRKRPGTVGICAAIMNHYKIDAVPHLICGGFNLQETENALIDLAFLGIDNV
LVLRGDAAKNETLFEPEKNGHAYALDLLKQTVNLNNGIYLEEDIRDGYKTKFCIGVAGYP
EKHFEAPNMESDLRYLKLKVDAGADYVTTQMFFDNKKYFEFVKKCREAGIEIPIIPGLKP
ITSKKQLSVLPRTFHVDIPTELSNEILKCKTDADVEIVGTEWLLAQSNELKKAGVPVLHY
YTLGKPHVIANVVKELV
>W6YUG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bipolaris oryzae ATCC 44560|TrEMBL
MHISQKLAQAKREGKPTFSFEFFPPKTAQGVQNLYDRMDRMHSFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALREAYQAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDDVDELIDHLKEKVDAGGSF
IVTQMFYDTDLFLEWVRKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTKCHIPDDWTKAL
EPVKNDDVEVREVGKTLVADMCRRLIDAGITHLHFYTMNLAQATRMVLEELELLPDVESP
LEKPLPWRPSLALNRREENVRPIFWRNRQRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPLTIRDFSNLFVRYMEGKLESLPWSEQPITAEASSIRDDLID
LNRRGFLTINSQPAVNGVKSSDPVFGWGPRNGYVYQKSYLEVFVSPEHIAEIITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDVIDTWYLLNIVHNDFHATRGIFPIFNGLEVKDMDKPLHTPSADL
PNANGSETANGANGVNGTNGTHKEESPSLVDVAKAAAIEVTNGMKSLAVSN
>F0KPQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus (strain PHEA-2)|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIDKVLHFSGK
ARDIQDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKEHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTQHAYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDHVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLELEALEELWNSLWQVTTGKEFSPEITRFSR
QPSSKQLIKYRQLHVMHEAMFGSKIAKGFGRFIFKASFWENTLVAKLLLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQT
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>W2QTM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora parasitica (strain INRA-310)|TrEMBL
MGKIIESIRSAYAARADDASARPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGAERWSPVEGGLSNAVDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIQWISDCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPEKVLTALDAIKNDDAAVRRYGTQLAVETCRRLLAAGVNSLHFYTMNLATT
VTQVLEGLQLLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRTELWGTPQTEEDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAAIRENLQWLNSNGFLTINSQPRVNGAPSSDPSVGWGGDDGVVFQKAYVEFFVA
PEKIAHLVKVMRRDYPQLSFHALNRRGDEHRNTPLHSVTAVTWGVFPGIEIVQPTVVDSD
SFAAWKDEAFELWQTQWASAYPEGSCSREVIQHIYDSYFLVNIVDNDYANDDSDIFSIFT
RIITEAMDKEELRTRVLELEARREKMFDTLASFQSLQKDLNGELRAAHSELAGVRGENLQ
LKEKVRQLEAQLALASL
>A0A8F9TWY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleiharenicola sp. KSB-15|TrEMBL
MADLLSTLRTQALLTDGAMGSLLFKRTGRLSETNHVYEAFNVDQPELIRRVHLDYLAAGA
RCVKTNTFGANRWQLRPFGIEARVAEINRAGVRRAREAIAEHQERHREAGPFFVLASIGP
TAEPLANAMEAAECYHEQIAALVEAGADALLLETFSSPAQLELVLARVRMWPQPPLVIAQ
VTLRGGVSGTGLDPEPVAWVRRMAELGVAIAGVNCCAPWDASAFVDAVKDEPVVRQGTLL
LAVMPNAGGFQRIGSRLMTTVNPEAAGKMARTLFERGVRLIGGCCEMHPPHIEEMRNYLQ
SRQTTAPATAVSRAETPARAPAGDEEKRGNGRFSLKLKAGGFVVSIEALPPRGTDGGVVE
RKVEFVAQLAASGLVDAVDFTDGSRGIPLVPPGDFIQLVRERLGWTAATGDALEMIPHFT
GRDLNVMGVQGRLIGYHANRIHNVLFVTGDPPKMSPTYPRSTAVFDLDSVAMIRLTHRGL
NAGVDFGGQPLGRHADPRTHFTIGSGFEPEARNLAREVERLQQKIEGGVDYIMTQPVFHA
GPLGVLDAFRGQTRCLVGVMILTSYEHAQRMAQVPGVVVPDALLERFAALPQVADQTKLG
QEIAAGQIRDLVREGWAGVYVMSTAVGAGVVDVLRAGLG
>A0A5P6P831|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium betae|TrEMBL
MSGAMTDPTTPAHADGQDGHLAVKRPAISFEFFPPKTEDMERNLWDTINRLAPLDPKFVS
VTYGAGGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVAL
RGDPAGGIGTPYSSHPDGYQSSADLVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTL
KAKVDSGATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRAGT
SVPDWFAAKFEGLDDDAETRKLVAATVAAGQVQKLAKNGVNTFHFYTMNRADLVFAISHL
LGIRAKSAQKAA
>A0A369M3D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonibacter pamelaeae|TrEMBL
MRSVADIYAAARAAGRQPVSFEIFPPKGDLTLEAAHEVAAELADLLPDFVSVTYSAGGSG
NRQATADVAAMIHDDFDIPTVAHLTCLGATEESISRAIDDLKRKGIASVLALRGDRTADA
PAAEGPFRFAKDLVMRLADEGFCVGAAAYPEGHIECTDFRASVAHLKQKQDAGACFFVTQ
LFFDNSYYYRFREAADAAGIAVPIACGVMPFLGKAQIQRMVFMCGASLPSPIIKLLAKYE
DDPGSLRAAGIEYACAQLTDLQQHGADGLHVYTMNQPDIARACAGALRASWRPAGEAAVR
GAGEPAGGRA
>A0A1Y2SJR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus beddingii|TrEMBL
MSFFHANQREALNQNLAELDGQIRVSFEFFPPSTTEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKEKTGLDAAPHLTCIDANRAELRNIAHDYWQSGIRHIVALRGD
LPNDGCKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATLTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A1H4CAW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella ruminicola|TrEMBL
MSVTEFIHQDKEAKRFSFEVLPPLKGTGTAKLFADIDKLREFDPAYINITTHHSEFVYRE
LENGQFERRRIRRRPGTIAIAAAIQQRYQIPVQPHVICSGATIEDIEYELLDLQFLGIND
LLLLRGDKAKEDSRFQPTPGGHAHTTDLMAQVKRFNEGFFADGTPIKNPGRPFDYGVACY
PEKHEEAPNLEMDMQFLKQKQDLGAQYAVTQLFFDNEKYYAFVEKARQMGITIPIIPGIK
PMAKLSQLTVVPKTFHCDIPEPLAKEVVKCKTDEDAKQLGIEWTTQQCKDLYAHGVHNIH
FYTVSAVDSVAEIVKRLVVRG
>A0A0R2U7P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR86 cluster bacterium BACL1 MAG-120820-bin45|TrEMBL
MKISYEFYPPKDLNYQKIIEEYSLLSNFGPRFISITYGALGSSQEKSVGLIKAFKESVDV
EVVAHLTLVGKSKQELSFIVDEFSSMGVTKIVALRGDVAEGSFIAHQDGFQNTAEFVDFL
AKKKMEVFVSAYPEPHPDSKGFDFDVRLLKDKTLAGSRQSISQFCFSMHEYQRLVDAIKD
QNIQNDLTAGIMPIYNIASLCSMAERCGIKIPPEIIGQFSEDPQKNEQASIKICIQQLED
LQAMGINNFHFYTLNQSSLLKKIFNEIGF
>A0A1H9MGL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. NFACC02|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARTLAGYSPDFFSCTYGAGGSTRDRTINTVLQLE
KEVNVPAAPHLSCVGDSKNDLRGLLTQYKEAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEEDLKNFVRKANAGADSAITQYFFNADSYFY
FVERIEKMGVTIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDAASIVAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>Q5M4U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)|TrEMBL
MTLIKMLLSQQKSKTKKVKLMTSQTPSLSFEVFPPNPAVGNEKILLALDDMKGSAPHFIS
VTASNNKYNIKETTVPLADHIQNDLAIPTIAHLPAIYLSKEKVADTLRELDAVGVNRILA
LRGDIIPGVEPLKDFRYATDLIEFIKAEAPNFDIIGACYPEGHPDSPNQISDIQNLKKKV
DAGCSSLVTQLFFDNERFYDFQDKCTLAGIDVPIYAGIMPILNRNQALRLLKTCENIHLP
RKFRAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNAETARHIYEATHS
LFKHHSQVGAL
>A0A1H6JR36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella ruminicola|TrEMBL
MSVTEFIHQDKEAKRFSFEVLPPLKGTGTAKLFADIDKLREFDPAYINITTHHSEFVYHE
LENGQFERRRIRRRPGTIAIAAAIQQRYQIPVQPHVICSGATIEDIEYELLDLQFLGIND
LLLLRGDKAKEDSRFQPTPGGHAHTTDLMAQVKRFNEGFFADGTPIKNPGRPFDYGVACY
PEKHEEAPNLEMDMQYLKQKQDLGAQYAVTQLFFDNEKYYAFVEKARQMGITIPIIPGIK
PMAKLSQLTVVPKTFHCDIPEPLAKEVVKCKTDEDAKQLGIEWTTQQCKDLYAHGVHNIH
FYTVSAVDSVAEIVKRLVVRG
>A0A371AZN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerosacchariphilus polymeriproducens|TrEMBL
MKIKEIFEKKKPIVSFEIFPPKKETSIKHIDETLKYLSELNPDFISVTFGAGGSSNHNQT
VELAKKIKHVYQVEPLVHLTCLNYSRSEIAYILEELKEADIQNILALRGDVNSKIERKAD
FCYASDLVAFIKKYGDFGISGACYPETHMEAANEKEDILNLKKKIENGAEHLISQLFFDN
DIFYNFREKVRLADIRVPIEAGIMPVTNKAQIEKMVSLCGASLPGKISKIIQKYGDNKEA
LFDAGIAYAIDQIVDLLAHDVDGIHIFTMNNPAVARKITKGIKALI
>A0A1M7FYS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella ruminicola|TrEMBL
MSVTEFIHQDKEAKRFSFEVLPPLKGTGTAKLFADIDKLREFDPAYINITTHHSEFVYHE
LENGQFERRRIRRRPGTIAIAAAIQQRYQIPVQPHVICSGATIEDIEYELLDLQFLGIND
LLLLRGDKAKEDSRFQPTPGGHAHTTDLMAQVKRFNEGYFADGTPIKNPGRPFDYGVACY
PEKHEEAPNLEMDMQYLKQKQDLGAQYAVTQLFFDNEKYYAFVEKARQMGITIPIIPGIK
PMAKLSQLTVVPKTFHCDIPEPLAKEVVKCKTDEDAKQLGIEWTTQQCKDLYAHGVHNIH
FYTVSAVDSVAEIVKRLVVRG
>A0A0H2VIK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)|TrEMBL
MSHLLNQLKSNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKSFGLEHKVKEIHQAAVQIAKHAANEDTIILGTVGGFRGVRQEDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELTRIVTATRQKYDIPIIAQLTASNTNYLVDG
TEINAALKYVVECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDIAQELINEGVRLIGGCCGTTPEHIRYIKSAVKHLKPVKDKKVIPINKAS
SQKQTRVLKQNLTSKVKNGPTVIVELDTPKHLDTDTFFDNVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQRYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGINTDGDALKKHTNFNIAGAFDPNVRKLDGAIKR
LEKKVASGMSYFITQPVYSKEKIIQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSDDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A1G3L7E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium GWB1_48_6|TrEMBL
LAWAQFLQDHEKVDVAGMNLIGPSDALEALEILKKVVKKPLAVQPDSGFPKEVDGRQFYL
TTPDYFAEYAKFFLDMGAGIIGGCCGTTPEHIEKMSRTLVSFDRGRKNTSLSVSETSGKA
RPEIPQDQRSNLGKDLALGNWISTVELVSPLGWDLTKILEKAQALASAGVKYVNIPDGPR
ASARISALTTAVEILRKTGLEPILHVATRDKNLLGLQGDLFGGHAQGLRDVLLITGDPPK
VGKYPNVTGVFDVDSIGLTRMVKGFNQGLDFGGEELPDTSSFVYGCGVNPAFPSMEMELE
RAFKKAEAGAEFFITQPVWDQDKLQEFLEKLKATGVPVLLGLWPLASYRNALFLNSEVPG
VVIPQDILERMKKHEDKEAARAAGVAISREILKRMKPWVNGIQVSPPFGNVKTALEVLAP
>A0A0B5I9Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces vietnamensis|TrEMBL
MTPTFSFEFFPPKSDKGEQTLWDAIRRVEALKPDFVSVTYGAGGSSRDRTIEVTKRIVTE
TTMRPVAHLTAVGHSAAELRAIIGAYADAGVRDVLVLRGDPPGDPRGEWTPHPDGFRHAY
ELVELVRSLGEFRIGVAAFPEGHPRSVDARSDLAHFVAKCRAGADYAITQMFFDPEDYLR
LRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAKDDPAASYRIG
VEHATRMGLRLLDEGAPGLHYITLNKSTAALEIHRTIMSARRVAAHV
>A0A1T4MB52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Consotaella salsifontis|TrEMBL
MAFRQTRPRINVSFEFFPPKTEKMEETLWASVQRLAPLAPEFVSVTYGAGGSTRERTHHT
VRRILTETRLKPAAHLTCVDASRQEVDEVIRQYRDTGVRHFVALRGDSASGVGEKYRPHP
EGYANAVELVAGLKAIDDFEISVSAYPEKHPESPDFATDIDMLKRKVDNGATRAMTQFFF
DNDAYERFVERVRRAGIYIPIVPGIVPIHDFTKIARFSAACGASIPAWLAERFEGLEKDP
ETHSHVAAAVCSEQVLDLVDRGVRDFHFYTMNRAELVYSICHILGLRPQPEEPEENAAAA
AGASA
>B2Q6I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia stuartii ATCC 25827|TrEMBL
MLESEGMYMETALSFEISAMSKIDNTLEHLLKNTEELTPLFYTVNTEIGKTEWRDTYNTC
CELKNLTHVNVVPHIAINNKDECELCFIIEEYLKNDITELFVIRGDRHRFDEELPFNYGI
ELIDFIRRRYPEVMIKSSIYPDYHKESITPEIEIDWLRKKLQLGVTELISQLCLNKNAFS
YMKKQLGNDIPITISMMPMLNFSFIESFFKNNAIDYPLWIKKHIRPSNINNHRAFGIQLT
QFLIGEYIKENKRLHFFTLNNAEMVKKLFDKLR
>A0A3N4YVD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myceligenerans xiligouense|TrEMBL
MAVETPHPSRPTISFELMPPRRPDAAPKFWETARRLVATHPDFVSVTYGAGGGDRATARA
VVAKLLEGTPVLPVAHLTCVGASREDVSEVIDDFFDAGVRSFLALRGDPPKDQPDWRPPA
DGVHSSIELVRLLRDVEERRCAASPATALRGAARPLTIAVATFPNGNADAGTTRAQEVVR
LLEKQEAGASFAITQLFYEPESYTGFVEAARNAGVTIPILAGIIPTTEPRRLRRVEELTG
VVPPPRLLAELDDLRLDDGSPDAEAQHAHGIEYSVRLAQAVLDSGAPGIHVYTFNKHRPA
LDLLSGVGLTTASA
>A0A427HV05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas oleovorans|TrEMBL
MSQQRRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTVNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGDHFHIEVAAYPEMHPQARNLEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRVFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLSR
>K1XFY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marssonina brunnea f. sp. multigermtubi (strain MB_m1)|TrEMBL
MHIKDMLSEAERSGQTTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVSVAQSQYGLETCMHLTCTDMGQEMVDAALRDAYKAGCTNILALRGDPPREKEK
WVATEGGFQYAKDLVKHIRDTYGNHFDIGVAGYPEGCDDQDDPELLLEHLKQKVDAGATF
IVTQMFYDAENFIEWLGKVRAKGITVPIVPGIMPINTYASFLRRCSHMGCRIPPEWSAAL
EVVKNDDSAVRNIGTGLVAEMCRKLLAAGIHHLHFYTMNLAQATRMLLDELKLTPSEQRP
FKHALPWRQSLSLGRRDEDVRPIFWKNRNKSYVTRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNRKLWGEPKSIKDIADIFVKYLENGVESLPWSEAPITNEADSIKSDLIN
LNKRGMLTINSQPAVDGVKSSDPVYGWGPSNGYVYQKAYLELLVSPTLMPQLISRIELDP
DLTYYAVNRLGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVEAISFLAWKDEAFRLGKDW
AHCYSALSPSRQLIDSLMDSWYLVNIVHNDFHQTHGLFPLFDGMEVKDIDIPFEPLPETK
GLVTETNGINGSAPTEKENITLTSAPTETENVTLTNGSVAK
>A0A4R6QGI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paucibacter toxinivorans|TrEMBL
MAHNDKCPVSFEFFPPNTPVGAEKLKAVVQDLSVLSPQYFSVTYGAGGATRDKTLATVSA
IAQMGFEAAPHLSCVGSTREGIAEILSTYRAQNIRRVVALRGDLPSGTATAGEFRYASEL
VRFIRETQGADWKIEVAAYPEYHPQQRYAARDLQHFADKMRAGADEAITQFFFNPDAYFH
FVDEVRALGVDAPIIPGIMPFHNYARIAQFAARDGIEIPRWVALKMEGFMDDSASIRAFG
LDVMTRVCERLIAGGAPGIHFYTLNQSALTLELCKRLGLGTKV
>F3QXZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraprevotella xylaniphila YIT 11841|TrEMBL
MNVIDLIQNHKGTAFSFEVLPPLKGAGIERLFHTIDTLREFNPAYINITNHRSEYVYKDL
GGGIMQRLRIRRRPGTIAVAAAIQRHYDIHVVPHILCSGYTREDTEYMLLDLQFLGISDL
LVLRGDKAKEDPAFRPTGDGYSHATELIGHINRFNDGFFVDGSPIKSPGTPFSYGVACYP
EKHEEAPNPEADLAVLKQKADMGAAYAVTQLFYDNAKYFDFVDRARGAGITIPIIPGIKP
FAKLSQLSVVPKTFHCDLPQDLALEIRKCKTDEEAKQVGIEWTVEQCRELIGHGVPSIHF
YTVSAVDSIREIARQIY
>A0A0L0MAE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Burkholderia verschuerenii|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRASRKELAKLTPKFVSVTFGAGGSTQQGTLDTVLEMAS
EGFEAAPHLSCIGSSKDSLRAILSQYREHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQEHGDWFNIEVAAYPEFHPQSKSPRADLENFARKVKAGANSAITQYFYNADAYFTFVG
EAKKLGVDVPITPGIMPITNFSQLMRFSDMCGAEVPKWVARRLESFGDDRESIREFGLDV
VTGLCRRLIDGGAPGLHFYTLNGAQASKSICERLGFKSA
>A0A397NBL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas oleovorans|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTVNTVLQLD
GDVKVPTAPHLSCVGDSKAELRELLNLYQNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRVETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGANSAITQYFFNADSYFY
FVERVQKLGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIDSIQAFG
EQVISEMCERLLAGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A327V165|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Amel2xB2|TrEMBL
MAIGISATRTDNAATVRELLATGKPSYSFEFFAPKTEKGERSLWNALRRIEAVSPTFVSV
TYGAGGSSREGTVRNTERIANETTLTPVAHLTAVSHSRSELRNVIGQYADAGIRNVLAIR
GDPPGDPMGEWVKHPEGLTYAAELVELIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVD
KCRAGADYAITQMFFRTEDYLRLRDSSAAAGCETPIIPEIVPVTNVNQIETFARLSNATI
PDELADRLRAVEDDPAAVRSVGIEYATEMCATLMAEGVPGLHFITLNNSTATLEIHQNLG
LRNRS
>A0A7T2VU28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aerococcus urinae|TrEMBL
MKTKELFKGKTLFTYEVFPPNAKSSSSSIYKTLDGLKELDPDAISVTCGALGSDNRLKSI
EIASLIKNYGIESIIHLPCLYESRGSIDDKLAELQATNIENILVLRGDPKPGQSPKEDFP
YAADLIRYIKSKYDFNILAACYPEGHVDSPDPITDIRYLKEKVDAGSDQLISQLFLDNDY
FYRFLERADLAGINVPIEAGIMPVTNKKQIENMARICGVQIPDKFRRAMEKYQDNPLALR
DAGLAYAIDQIVDLISHGVDGIHLYTMNNPYVARYIYQAVKNLL
>A0A195FBA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trachymyrmex septentrionalis|TrEMBL
MRNLILKNDMCERNDADGNNPSTSDFHIENPRKTVVDLRQLLKDKINKNEIFCSFEIVST
RKSDAFYRRLLIDMEEYSPLFYALTWHNETSSDIDGYLPLDLVKNFPANTLLHLAAKGLK
CDEVIYILKKALAFGIINIFALQGDSLSENGDFEHAADLVDFIRQRFGNTFCVCVAGYPQ
MHPESPSKELDLHYLKAKVEAGADFIITQICFDSRVLINFVRDCREIGIQIPILPGILAP
TNHACLEKMIDICRLGVPIKIKEDLAQIKDDDQAVRKYSVDLITQIITDVIRNGATYGFH
LFTLNRLSLVAEICKRIESFKAENL
>A0A897HI22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia megaterium|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINVAGVKLAKQAANDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLNEGVDGLLFETYYDFEELKTVLTLARKETNKPIITHVSLHDIGVLQDGR
PLADALKELEDLGADVVGLNCRLGPYHMIQSLEEVPLPDRAFLSAYPNASLPAYVEGKLE
YETNEDYFVESARLFREQGVRLIGGCCGTTPAHVRAMSSALKDLPPITSKVVKMRPAVTV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRIRGEVEGLAIAKNLIDTAYELFDGIYLITPFMRYEMTEILTRYI
HDKQLVTSERKI
>W2SE52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyphellophora europaea CBS 101466|TrEMBL
MHISKKLSLAHTQQKPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
QLTCEMVSAAQAHYGLETCMHLTCTDMERDKLDEALNLAYKSGCTNILALRGDPPRDQEK
WEAKDKGFRYAKDLVKHIKTTYGDHFDIGVAGYPEGCDDQDDPDLLLDHLKEKIDAGGTF
IVTQMFYDVEIFLDWVSKVRKRGIDVPIIPGIMPISTHDAFLRRANWAKCQIPESWHMAL
EPVKNDDAAVRDIGRDLVAEMCKKILDAGIYHLHFYTMNLAQSTRMVLEELSMTPETSGV
PLDKPLPWRQSLGLNRRDETVRPIFWRNRNTSYVARTADWDEFPNGRWGDSRSPAFGGLD
AYGIGLKGTNEANIKLWGEPTTLRQVSELFVKYLKGDLDRLPWSEGKITEETDSIRNDLI
KLNSRGFLSINSQPAVNAAKSSHPVHGWGPKGGYVYQKAYLELLVFPSVFDKVMERLDAN
PNLTYHAVNKDGRLITNAPDEGPNAVTWGIFPNREIVQPTVVETVSFLAWKDEAFRLGHD
WSSCYPSDTATRRLIETIMDECYLVNIVNNDFHESHEIFEIFDGLEVENFDRVFEAPAAN
GRQNGVRNVVNGDAKADDVEKAVKQDPAKVPFQAALRTADHQRLNESGNVPN
>A0A517YS02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poriferisphaera corsica|TrEMBL
MHAKDIFEQHSTTFSFEFFPPKTEASAEALFAAVKELEALKPSFVSVTYGAGGGTRELTH
DLVLRIKKETQITTVPHLTCVCHSESEIEAILERYAKEGVENILALAGDPPVSVGGDDGY
DRSQDAFQHASDLVRFIKKFNDSGKHPNGKKGFGIGVAGFPEGHPGTPNRLLEMDYLKAK
IDEGADYICTQLFFENRDFYDFRERCELAGIDVPIIAGIMPITTAGGMKRMAELSAGSRF
PASLLKAVQRANGDAEAVKRVGIHWATEQCRDLLDNHVRGLHFYTLNRSDATKEIYLNLG
ARDSAALGG
>A0A2P2D729|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira johnsonii|TrEMBL
MKKILEIYKTAKAPVYSFEFFPPKTPEGETKLFEAVEELSKVDPGYITVTYGAGGSTRDK
TIRITSELAKKFSLPAAAHFTCVGGNKDEIRVILKQIRESGIENLMALRGDPPKGEEAFK
KVEGGFGYASELISFIKQEGFDFCMGAACYPEKHPEAASLESDVDNLKRKVDSGASYLVS
QLFFKNSNFESFLDLIRKKGINVPVIPGIMPITSFTQIERFKSMAACEFPEKLVSDLEEV
KDNQEEFYKRSISFSVNQCRELVKMGAPGIHLYTLNQSPASLDIVRELKN
>A0A3D0JQ25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MTQERRYSFEFFPTKTEAGHEKLMDVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLNLYKNAGIRRIVALRGDLPSGMGMASGELRYANEL
VEFIRNETGDHFHIEVAAYPEMHPQARNFESDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSDSIRAFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLDLKR
>A0A2E2GAV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSHTRSHSFSFEFFPTKTDAGHEKLLATARCLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVSTAPHLSCVGGSKQELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEXIRAETGDHFHIEIAAXPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKXGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMESIQT
FGAQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWDNLKLGR
>A0A2M7CDS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG03_land_8_20_14_0_80_45_14|TrEMBL
MSFKEQLESGKFVVVAELQPPKGNDLSELYEYTELLKGRVDAINIPDLQNAIMRLGSLSV
CTLLKARGMEVIYNLSCSDRNRLALQSELLNASALGLKNVLLLQGDHPSIGDHFEAQAVF
DLDVMGLLGTAKRLQEGYDLMGNDLQGKPQFCVGAQINATAKGHVLDLEIMDMEKKIRTG
VDFFFTNSIYDVSLFEPFVKKVAHFKVPIIVAITLLKSVGMARYVNKHVEGASIPDSIID
QLMKASDKQKVSNEIAGGLIKAFKPLCQGVQLIPIGWEKQIPTLLDDVGL
>A0A3D3M8N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MTQERRYSFEFFPTKTDAGHEKLLATARTLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRALLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRQETADQFHIEIAAYPEMHPQARNFEDDLANFVRKANAGADSAITQYFFNAESYFY
FVERVQKLGVKIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EEVITQMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A5P2B5V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces venezuelae|TrEMBL
MTALRALIDQDTPSFSFEFFPPKSDAGARTLWKAIRRIETLAPTFVSVTYGAGGSSRDRT
VEVTKRIAAETTLRPVAHLTAIGHSVAELRHIIGQYADAGVRDVLAVRGDPPGDPGAPWT
PHPDGFTHAHELVRLVKESGDFSVGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQ
MFFDVEDYLRLRDKVTAAGCTTPIIPEIMPATDVRQISRFAQLSGAAFPEHLAHRLEAAR
HQPAEGHHIGVEHATAMAQRLLAEGAPGLHYITLNRSTATLEIHRNITDARSTPHDLAAH
H
>A0A1G0LMU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium GWC2_48_7|TrEMBL
MRIVDLLSRNNQFVSLEFFPPKERTEWPSFFKTVERLGSLSPLFASVTYGAGGGTGSDTL
EIVSRLAKDHGLETMAHLTCVGAQSATLLKFLDDLSTAGVNNVLALRGDMPKDSPPESSV
CNPLLNASDLVAFIRKSHPDIGIAVAGYPETHPEAETPEKDLSYLKLKIDQGGDFIVTQL
FFDNQLYYDFVSRARAIGITKPIIPGILPVVSLKVINRIVSLCGATIPAAFMAELEEADR
SGGATAVQKVGVKYARKQAQELLAAGAPGVHLYTLNRAEAVLEIADGLL
>X0A3P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. melonis 26406|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>T5AIP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243)|TrEMBL
MHIKDMLTEADKGHQPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGREKVNNALKMAYKAGCTNILALRGDPPRDQDK
WTATDDGFQYARDLVKHIRETYGNHFDIGVAGYPEGCDDNKDEDELLDHLKEKMDMGASF
IVTQMFYDADNFIRWVAKVRDRGITAPILPGIMPIATYASFVRRANHMQCKVPKHWMDAL
EPVKNDDVAVREIGKTLVADMCRKLLANGISHLHFYTMNLAQATRMVLEELSWAPCAERP
LHHALPWKQSKGLGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPATVRDLANTFVRYLDQEIDSLPWSESPLTGESDMIKQNLVA
LNKRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPPETVGAIISRIDNRP
SLTYYAITKDGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
AHCFESNTPTRALLDKVMSEWYLVNIVNNDFHDNAAIFELLKDVEVEELDATQAA
>A0A5C2P090|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium pseudotuberculosis|TrEMBL
MDVPSKREDFVSNPLRYRVMSASHIPAAYQRSITEVLKMPSPGRIPFSVEFMPPRDAAAE
QRLWKAAEAFHDLGTAFVSVTYGAGGSSRERTMRVAHKLSKLPLTTLVHLTLVEHTEAEL
VEILNDYAAHGLSNLLALRGDPPGNDPMAEWLATPGGLEYACELVELTKKNPETAHFQVG
IASFPEGHYRAPTLEADTEFTLEKLRAGAEFSITQMFFDIEHFLRLRDRLAKADSEHGNK
PIIPGLMPITSIRSVQRQMELAGASLPRELERQLFDAAKGDEEAHKQDIRKVGIELTTQM
AEKLIAEGVPDIHFMTMNYVRATQEVLHNLGMAPAWGTEHGHDAVR
>A0A5R1NRK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT3-29-2|TrEMBL
MPDTSDPACGNIPFSFELYPPKSDAATSALHATIKRLAAAGPEFISVTYGANGSSRRSSL
NVLTHLLRTTTVDPLAHLTCVGSSNAEASRLIREFLDAGVRNFLALRGDPPEGTREGDAF
LGDLGSAAELVQLIHRVQAERVPYREAAIPGLPAARTIKREREKVRIAVAAFPNGHPRSR
STTQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRHATELARKLIAGGAPGLHLYAFNQHE
TVLAVLERCGLLTPTPAPSASEFPASHPVKEYS
>D8ECE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli MS 119-7|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3D2D9D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MTALNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQAR
>A0A0S9KRQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodoferax sp. Leaf265|TrEMBL
MNTDSPALPVSYEFFPPKTPEGVAKLRGVRQALYARKPSFCSVTYGAGGSTQQGTFGTVG
EILAEGVDAASHFSCIGATKDSVRTQLAELRAMGVKRLVALRGDLPSGYGAGGEFQYASD
LVAFIRAETGDAFHIEVAAYPEVHPQARSPEADLQAYAAKVRAGADSAITQYFYNADAYF
RFCADGQRLGLDVPIVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIKSF
GLDVVTTLCEQLLRGGAPGLHFYTMNQSVATLELCRRLGL
>A0A0D8ID75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium aceticum|TrEMBL
MSLLRNAIENGEFAVTAEMAPPKGTDFHHLMECARAIKGRVHGVNVTDFQSAVMRATSLA
TCKLLKDEGLEPVLQMTGRDRNRIAIQGEFLSAAVFGIPNVLALTGDHTVVGDHPGAKPV
YDLDSVGILQAATTMIGGKDMVGNDIEGGVDFLLGACVTPRFDPLEAQILKMEKKVKAGA
KFFQTQAVFDMDTMREFREKTKHINAKVLAGIIPLKSAPMAKFMNNNVPGIFVPDELIER
MKNTEKDLRVQEGIKIAGEFIRQLREENLCDGVHIMAIGAEENVPAILDAAGL
>A0A2R4MDE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritalea myrionectae|TrEMBL
MSDTPIFSTPDRLSRQSEEELAKLDLSFEFFPPKTDKMEARFWETLERLAPLSPRFVSVT
YGAGGTTRGRTTKMVSRIEKETGVKAAAHLTCVDATKDEVNEVVRGYKEAGISRIVALRG
DPPEGVGQPFQPHPQGYRNAADLVAGIRTIGNFDISVACYPEKHPQSPDWYAEFENLKRK
IDAGASRAITQMFFDNDLYLRFVDRARNAGIEAPIVAGIQPIHNFTQISNFAGRCGATIP
NWMAERFEGLEDDPETHALVAAAVAAEQVTELVDRGVTEFHFYTMNRSPLVYALARLLGR
RPQISRG
>K1GR93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium periodonticum D10|TrEMBL
MKIADIYKGKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIADRIKNQNGVESVAHLTCIGAKKEEIDRVLEDLEKHNIENILALRGDYPVDRELEVGD
FSYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A840RJ78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Silvimonas terrae|TrEMBL
MSQPPISFEFFPPKTAEGTEKLRITRRQLAQFKPEYCSVTFGAGGTTQDGTLNAVLDIQS
EGLAAAPHLSCIGSSRASVADILQRYRDNGIRHIVALRGDIPSGMVDVGEFRYANELVAF
IREQHGDWFQIEVAAYPEYHPQAQSAEADLRAFVNKVNAGADSAITQYFFNADAYFRFVD
EVTARGVKIPVVPGIMPIQNFSQLARFSDMCGAEIPRWLKLRLQSFGDDSASIRALGLDF
ITELCDRLMQQGVPGLHFYTLNAAGAVSTICQRLGR
>A0A2M8TAP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CT7|TrEMBL
MMNAVIREYLKDNILVTDGAMGTYYSKVTEDYNSFCEFANIDNPNIISNIHGGYIKAGAK
LLRTNTFSANTLTLDVSREKLKEIITKGYMIAKKAAAGKNVFVAADIGPINRFEMEKPIE
YVIDEYKFIVDVFMDLGADIFVFETLSSADYLEKVSEYIKSKNRDAFILTQFAVMQDGFT
REGISIKRIIEEIKEIKSIDAYGFNCGSGPTHLYKIVKNLKIDGDIVSVLPNAGYPEIVN
ERMVYVDNPDYFADKVARIKNIGAKILGGCCGTTPKHIEKLVSKLNRNFGVLNHDIKVKE
ENTIKRIKENNKFWDKLLNGECPVAVELDPPFDVNTEKIMHAARVCKENDIDLVTVADSP
MSKVRVDSIAIAAKIKREIGIDAMPHMCCRDKNINAIRSSLLAAHIAGIRNILAITGDPV
TGIDKVNTKSVFNLNSFKLMNLISGMNKEVFKGDEISVGGALNLNVLNKEHEVARMNKKA
ENGGKFFLTQPIFEDKTIDFLSNMGKHEDVKIIGGVLPLVSYRNVQFINNELFGVNIPEE
YVERFKPDMTREEAEEVGVNLSVELINKIKNYVDGIYIVTPFNRIEMVIKILKKSGM
>A0A1L8I3U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillaceae bacterium G1|TrEMBL
MGSDLRQALQERLLVGDGAMGTYLYQLGVPIGSCLEELNITRPELVEQVHREYVLAGARL
LETNTFAANRERLARYNLGDRVQDINRAAVARARAAILDVQTQRLRSIAADERPPVFVLG
AVGGIRGTRPGSLTDEALADLYREQMAALLEAGVDGLVLETFVQLAELRLAVQVARKLDA
TIPLIAQLSVQESGRTADGASLAEAFAVLQDDGADVVGLNCSSGPHTMLRLLEQEPLPRD
IVLSAFPNAGLPGYQDGRFVYPSSAAYFADRTLEFWRLGARIIGGCCGTTPEHIAAVARV
LAHRAPQPVRSADEADGREPGAVGAADGRGRQASAEQANAPLTVAALHTAERPGTDSGTA
WRAGADQGLGFAGTGVDAPPLTELVRQRHTVIVELDPPRDLDISRYMEGAAVLKEAGIDA
LTMADNSLAMTRMSNMALGAIVKERLGLRPLVHVACRDRNWIGQQSHLMGLHALGIDHVL
AVTGDPTRHGDLPGAASVYDGNSFDLIRMIKQLNDGLAFSGQPLKSRTRFTVGAAFNPNV
RNWDKAIERLERKVACGADFIMTQPIYDPALFEQLYRRTRHLDVPIFVGIMPLVSYRNAL
FLHHEVPGIQLSEEVLARMSRVEGEDARREGVAIAMELLDEAMRWFNGIYLMTPFLRYEM
SAELTRYVLRKAAKARRRGEESEGRRWTTGR
>A0A1V4MBU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|delta proteobacterium ML8_D|TrEMBL
MISGSNLEQVLISGQFAVTGELGPPQNGNFDAVRDKARILKGHVDAVNITDCQTAIVRMS
SLAAGLIALAEGVEPVMQMTCRDRNRIGMQSDILGASALGIKNLLCLTGDHQKFGNHPQA
KGVFDMDSIQLLDMVRAMRDDRKFQCGDEIKSHEPRFFLGAAANPFADPFDYRPIRVAKK
VKAGASFIQTQIIYNVEKFARFMEIIRDLGLNEKVYILAGVTPPKSFGMARYMKKFVPGL
DVTDEVIERLKGAKDPKEEGINICVDIIKQVREMPGVAGVHVMAIEWEQAVPEIVSLAGL
FPRPMPKAVEPILRSSETIDLIVSKTRKDAKAEAEKALEQARAEAQASRDLVLKEKGKII
SEVSNLKRQVEEAGVIASRKETEIERLTREIEGKRAAGKGPVRTVRSSVSDDTGKAPSSH
DSRALISLRSGIEALRKGLGINEDQLEALRRLFQAEFLLSSGVDERVTAPFDESPGQGEM
PEKTQAESRQREVVSLVAKGNVLLHKNDRAGAIDSFKKALAIEAGDQKAREGLKKALEAF
EISVSSEDAAGPIVPEGLPPCPEGLSPEDWQRKWVIRLVATGNVCLHKGEVDKALKAFNL
ALDLQPDDKRAKTGLLKTDSGETAPVSAPAEPEVPERAEVPSAPGPKIAKVPEGVKTEAK
KRPPVTAAPTVTEDISVPELPKETRTLFERADSIPENLFTESCTGAIREVCLGEGEKAVT
LGGASTLPFHIFEGDMPRAPQVAFGILDSEPEDWPDVLSRYYSDVFSDPVAWARKCIDHY
GAKAICLSLVSTDPNGMNRPSSEAARKAQSVIEGIDVPLILWGCGNAEKDTETLREVTGL
VGNRKVCMGPLSDANYRSLGATAMAFHLPVVASSPIDVNLAKQLNILLENLGLSLDQILM
DPSIGAIGYGIEYSYSVMERIRLAALTQQDEKLQVPFICNLGREVWKTKECRLPSDAHMG
DQERRGVLMEAITASTLLLAGGELMVMMHPKAIALTEALIKGMV
>A0A8I0KZ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizorhabdus sp|TrEMBL
MTSVPLSQLEEARLALDTPLFADLAGDAAVSFEFFPPKTEKMEETLWQSVQTLAPLRPRF
VSVTYGAGGSTRERTHNTVARIARETDIPAAAHLTCVEASKAEIEDVARAYWEAGVRHIV
ALRGDPPVAGAAFVPHADGYRNAADLVSGLKAIHPFEISVAAYPECHPDSESPESDLANL
KAKFDAGATRAITQFFFAPEHYFRFCDQVRAAGITAEIVPGIMPVSNFAATKRMAAMCNT
EVPAWMGRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVRQFHFYTLNRAELSFAICHM
LGLRAEAKALENAA
>A0A6H9KA24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MSTLVELVAKNRRRPFVVCDVSPPRSGNTEALSALSSVTPDMFFVAANPGRTVRASSPSI
AQWIESNIKTPALFTMVTRDMNKTAMQTTLLGAHIMGLRNLVVVKGDNFNNSGCGTDKPV
KGFTPTAFIRSVR
>A0A5N7YYS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFKPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEPSKGGHKYASDLVKQIHDLGIGEYLHGKIESDVDNSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVDAGADYIVTQMFFDNQKFFEFVNQAREIGIDVPIIPGIK
PIATKTHLQMLPQVFKIDLPEALINEVIKCKTNNDVREVGIEWAINQSKELLDFGIPVLH
FYSMGKSDNILKIGREIF
>G7XN52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus kawachii (strain NBRC 4308)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDVQDPARDLPYL
IEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPQVLSKLEEVKHDDDAVKRIGVDIITDLVYGIRDLVSPGLRGFHFYTLNLEKT
VSFILERCELIPPYTEIDDSDALVDGGNLSAMDSSSYIAPNGAPIRTLASRRSSVSSIPH
NRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEEDSNGLNAETAVIQPELLTLIDKKGWWTLASQPALNGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNPDDPDPIDIN
PANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDETK
NDVWLVCVVGQEFGAGTEAGSEEEEDEKKWMWRELANSQ
>A0A8C5E177|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gouania willdenowi|TrEMBL
YPIIVSLNTHLNRLYENNIGASGGDSSKESSRCSTPVLDADRSDRLRDKMRKRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY
CGLESILHLTCCNQSKEKITAYLNKAKHLGLKNIMALRGDPVGSEWEDEEGGFNYAIDLV
KHIRSEFDDYFDICVAGYPTGHPEAETYEADILHLKEKVDAGADFVISQLFFRADTFLKF
VNDCRAIGIKCPIVPGVFPVQGYQSLRQLAKLSKLEVPEEITRVIEPIKDNDAAIRNFGI
HQAVEMCRLLLDSGIVPGLHFYTLNREVATMEVLRQLGLWNEDPRRPLPWAMSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQ
MWGEELMNEQSVYEIFTCYITAQSNPCGHKVLCLPWNDEPLAPETNLLKDELEKVNRRGV
LTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKILKKYEPRVNYH
IVNVNGRNWTNANDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIVKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLINEESCK
>A0A5N9C2U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MNHFGKNKKDNSQNIKFICDFSPPKGSDPSLISQVEELSADYISVAYNPGKSVGANSAFT
AFLIKKKYQKNVIFTLATRDMNTLSIQSHLIGANLLGLDNVIVLRGDPLNKSEKKIMSEV
NDISTTKTILSIKNLNEGKDFKNKHLKSKTNFTVGATIDLSKNLIQEKKLTLSKIESGAD
FLILQPIFKPDLLTQFLELYRNSYLEEINIPIFWGLQILEKNSLSFSEIPEWIQTDLEKG
RDGFSISQEILENFISEGYKSIYLVPSFFKKGKRNYKLAKSILDRYKV
>A0A3C1RCG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICASIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHGSAMELVHQINDLGRGKYLHNQDEICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGI
KPIATKKHLKVLPQIFKIDLPEDLINEVENAKNNEAVKQIGIEWAIAQCRELLEFGVPVL
HFYSMGKSDNIKKVAGALF
>A0A225ZBF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus neoformans var. grubii c45|TrEMBL
MKITEKLQKAEKESRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALKEAKSHGCQNILALRGDPVAGTST
WEPTPGGFMNAVDLVRYIHKHYPGDFCVAVAGFPQGHPETPDTPEGRAQEMEWLKAKVDA
GAEFIFTQMFYDTSIFFDWVKRVREAGINAPIIPGIMPIQNWEKFEKWVQRENIIVPSHF
YEALNPVRGDDEKVRQVGTKLVADMCKTILANKEAGIKGLHIYTLNLEKGARMLLQELGF
EGRREQIAPLPWRPSLTPSRREETIRPIFWANRTRSYLSRTADWDEFPNGRWGDSRSPAY
GDLDGYPVSIGITAPDAYNLWGHPTTSFDLHALFARFCRGDLAKLPWSTQPPASETSLII
EQLAKMNELGYLTINSQPAVDGVRSDDKVHGWGPAGGYVYQKAYLEFFVSPDLLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWAHLYPADSPSRKLITDTMNTSYLVNIVANDFRDGMSIFEPFLLDQTAVGKVVEGV
KGTVEGIVEGVKGVVGA
>A0A259FB71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium 17-64-65|TrEMBL
MTERTFSFEFFPPKTAEGAEKLRATRRQLAQLNPKFFSVTFGAGGSTRDRTLETVRDIQG
DGSEAAPHLSCIGSTEENIRDILNEYKSQGIRHLVALRGDLPSGSMDAGAFNYANELVEF
IRRETGDWFEIEVAAYPEIHPQARSYTEDLANFKRKVDAGANAAITQYFFNADAYFNFVE
DVRALGVSIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLEIYGDDLPSLRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPTTTIWQRLGL
>A0A5N6D5J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus parasiticus|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGTT
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNRDFTFAVDLVRYIRQKHGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYL
VEKTQAGADFIMTQLTYDIEAYTRFENMLRTHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVQIPPQILSKLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLRGFHFYTLNLEKT
VSFILERCDLIPPYSEDFDAIEEGGDISAMDGAQLRSLTRRRASSINSLPHNRVIVDKLH
ASEVSSKASVSHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSS
GLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFF
CPSKDYHSILKPLLQKHGHEKLAWFAANIKGDFESSLPAQTSDADPIEMNPDNVNCVTWG
VFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNDVKDDVWLVCVVG
QEFGAGTEMGSEEEEDEKKFMWRVLLNAKK
>A0A4Y3WC83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrobacter winogradskyi|TrEMBL
MTDAFAPTHNGLDARKRPTISFEFFPPKTEEMERNLWGTVTRLAPLDPSFVSVTYGAGGS
TRERTHSTIARILSETRLRPAAHLTCVGAPRGEIDEIVSRYRDIGVRHIVALRGDPPGGI
GTAYSTHPEGYRTSADLVAGIKRRHGDIEISVSAYPEKHPESPDIDTDIDMLKAKVDAGA
TRAITQVFFDNDLYLRYLDRVRARGIDIPIVPGIMPMHNFKQARAFVTKAGTTVPAWLAE
KFEGLDEDPETRKLIAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAICHLLGIRPDAD
QKAA
>A0A0N8K9Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. HL-58|TrEMBL
METQKQFKRRFSFEFFPPKTDKGWEKLQGVRNQLAEVDPDFFSVTFGAGGSTRDRTVQTV
LDLHKRGVSTAPHLSCVGATRDGIAELLDIYRENGVNRIVALRGDMPSGMGAAGELRYAN
ELVSFIREHSGDTFNLEVAAYPEFHPQARTAEDDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVSEMCERLLASGAPGLHFYTLNQAEPSLRIWHNLGLDNRDKISF
>A0A3Q9NKE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. NP-4(2019)|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEENPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRKDIAELLDLYKENGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARSAEEDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKMGITIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTKMCEKLLRAGAPGLHFYTLNQAQPSIRIWENLGIGEREKIAF
>A0A0N0TYN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL F-7442|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPTADWVAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPDSYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILSVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A8J5GWV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MSLVCSLYLPLFWSKPGPAACVPMQVAPASSSTRATTQSSSPSLGRKPPLRRLALEEGFE
LHRSRRRQHPMKKKLNVQLFAKVTRCLRLPQKTYMDTLTFGAPRFFRHLMDPSSKKIYVM
KFEVSKVCMETIMHLTCMNMPVEKIDHALNTIKANGIQNVLALKGDPPHGQDKFVQVAGG
FACALDLVQHIRAKYGDYFGITVAGSANS
>A0A453M7J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aegilops tauschii subsp. strangulata|TrEMBL
IQEAAANGRTVFSFEYFPPKTEEGVENLFERMDRMVAHGPNFCDITWGAGGSTADVTLDI
ANRMQNMVCVETMMHLTCTNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDKFVQVAG
GFSCALDLVEHIKAKYGDYFGITVAGYPEAHPEVILGEEGATEEAYSKDLAYLKRKVDAG
ADVIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTKIPAEIT
AALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMVISLSCSI
>A0A7W9DCX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. S3M3|TrEMBL
MADHNFSIEFFPPKTPEGTEKLRATRAKLSELHPKYYSVTFGAGGSTQQGTLDTVRDILA
AGEEAAPHLSCVGGTRESIRKVLADFKDAGVGRIVALRGDLPSGYGGAGEFRYANELVEF
IRAETGDHFHIEVAGYPEMHPQARSPQDDLQALVRKVQAGADSVITQYFYNADAYFQFIE
QTQKVGINVPIVAGIMPITNYTQLLRFSEMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTSLCERLLEGGAPGLHFYSLNQAAATTALWQRLVK
>A0A3A6P6Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfarculus sp|TrEMBL
MKAGSNLEKVLSAGHFAVTGELGPPQGNKAEEVRHKAAHLKGIVESVNITDNQTAVVRMS
SWAACKILLEEGLEPNYQMVCRDRNRLALMSDILGATALGIKNVLCLSGDHQRFGSHPES
KNVYDLDSLQLLAAFKKMRDEKKFLNDKDLEGAPEIFIGAAANPFADPFSFRVTRLAKKI
AAGADFVQTQCIYNMDKFREYMKQAVDRGLHEKVYILAGVTPMKSVGMANYMAKFVPGMD
VPEAVIKRLKGVDKKDQAKEGIKMAIEQIEEFKEMKGISGVHVMAIEWEHRAREIIEGAG
LLPRPQVD
>A0A2M7GJI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium CG15_BIG_FIL_POST_REV_8_21_14_020_66_15|TrEMBL
MPTPPTENLRQVAAFGRAAVAGASVAAPLPDDVEVSFEFFPPSTEGAEATLWNSIQRLAP
LRPKYVSVTYGAGGSTRERTHATVKRLLDETDLVPAAHLTCVDATTREIDTVAQDYWDMG
VRHIVALRGDPQDASGRYTPHPGGYAFACDLVAGLRQIGDFNISVAAYPEVHPEARSAKA
DMDNLKRKIDAGADQAITQFFFDTDVYLRFVDQARAAGIWVPIIPGIMPIHSFTKVANFS
RRCGASIPRWLSDLFDGLENDPDTHKLVAASLVAEQCRTLHAFGEKQFHFYTLNQADLTY
AICHMLGVRPKPPAGSDAGADKNQKTG
>A0A1Q7AF52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_2_20CM_2_66_4|TrEMBL
MDLLTALRSGASVFAAELRPPRAELAATEGIDAWIDTYHAVRRLTRQGTFVFLTDNAVGA
QEEDNLRHLVTNLGHDVPRERIVPFLTSKHTLDYCLSYAERAQQHGFSALVVLGGDKSVG
IPRCVGHAWQLRQLLRQRSHTIALGGWANPHADPERQVDFLVDPGFNAEFYLTQVVSHFD
ADKVSRFLRAAERRGVTLPGLFGVFYYRSANRRTLDALREFLPVPAEELAREFASGATAE
DVCARTIRTLVDAGARHFYISNLPVARAQQVLANILEKVGVTA
>A0A379ESQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella canis|TrEMBL
MSYAKEIDTLNQHIADLDGKINVSFEFFPPKNEKMETILWESIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKNIKQLTGLEAAPHLTGIDATPQELINIAKDYWSSGIRRIVALRGDEP
AGYAKKTFYAADLVTLLRSVADFEISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLMKMATITNVKIPTWLAKKYEGL
DDDQTTRNLVAASVAMDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGVRPIE
>A0A073IFT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter donghicola DSW-25 = KCTC 12864 = JCM 14565|TrEMBL
MPLADISFEVFPPKTVDASFKLWETAQALAPLEPRFFSITYGAGGSTRDLTHDAALVLHK
TSKLPVSAHLTCVGASVQETMEVAEKFHAAGVTDIVALRGDPQAGQDRFIPHPEGFANSV
ELIEALALQDKFNIRVGAYPDCHPDAASQHANIQFLKRKFDAGADEAITQFFFEPESFLR
FRDQCAAAGITKPITPGILPITNWTSARKFATRCGTKIPSWLDEAYRVAERDNRTELLST
TLCTEMCSTLISEGVEALHFYTLNRPELTRDVCRALGVTPQSTLSNVA
>A0A1E4HQF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium SCN 65-16|TrEMBL
MKVSFEFSPPRTEAAERTLWETVSRLTPLHPAFFSVTYGAGGSTRQRTHETVARLKSETG
IDAAAHLTCVAATQGEIDDVARAYWDAGIRHIVALRGDPPGGMGGKYSVHPGGYENAAAL
VTGLKKIGPFQISVAGYPEKHPDSADAKADLENLKRKVDAGADRCITQFFFEADDFLRFR
DNAATAGIHVPIVPGIMPVSNFQGITKMAGLCGSKVPAWLANLFDGLEDDLETRRMIAAT
VAGDLCRRLQSEGVEQFHFYTLNRADLTFAICHLLGVRPR
>A0A0J0Y3I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. BMA|TrEMBL
MKIIDHIKNANGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARSADSSFIPTKGGHCYATDLIEHIKNHNEGKFLHEDIETFKSDFCIGVAGYP
EKHFEAPNLNTDFKYLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPEELTDALSHAKNNAEAKEIGTAAMIKQCKELMDFGVPVLHF
YTMGKPEQTKQIARAIF
>A0A436RYJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.046.02.1.1|TrEMBL
LVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRAITQFFFDNDLYERY
VERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFEGLENDPQTHALVAS
AVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEATGSAAA
>A0A1H5G5H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter alpinus|TrEMBL
MSPPSLNRASAPLTHSAPTALSYELFPPKNQAAEAALWNTIRELESTNPDYVSVTYGANG
SNRDTAVELLNRLLTETSLLPLAHLTCVGNTADELAEIISELLDHGVRGILALRGDLPKD
APSQPRPGSLNYAADLIELIRRVEQRRSALLCAGKVAIGVAAYPAQHPESPSVEHDVEVL
LAKQNAGADFAITQVFFHADQYKDLVVRARRAGVIIPIIPGVMPLTSLRRVKRLGDITGV
APSTSLLDALGRADDAAESRRIGVAATVDLARAALDAGAPGIHLYTFNEHAAALEVLDKL
QLLRPGRPPVAPRAAPTDSARLVRA
>A0A3P1SF64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schaalia canis|TrEMBL
MTLLLTGSAPTKPRFSFEVFPARTGAAALALGHCVQHLSAAGPDFISVTYGANGAHRDGS
VDLLRYLRNYTDALPMAHLTTVREDRAAIKAVIHSMMDAGVHDFLALRGDPPRGMDESDA
SVAGSLSSVELIELINEVRGERPALTSVGRIAVAAYPNGHPLSRSRREDIDWLIAKQEAG
AQLAITQLFFHADEYLGFVAEAQQAGVTLPILPGLMPVSTLGQLRKVASLAGRPAPADLL
AAMEKAGGYAPELGVAYTVAVAQEILQGGAPSVHLYTFNRHEYVLEVLRELDLLTPIAFI
>A0A160PS28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium suranareeae|TrEMBL
MSTTNIPASSQWAISDVLKRPSPGRVPFSVEFMPPRDDAAEERLYRAAEVFHDLGASFVS
VTYGAGGSTRERTSRIARRLAQQPLTTLVHLTLVNHTRDEMKAILQEYLELGLTNLLALR
GDPPGDPLGDWVSTEGGLNYASELIDLIKATPEFEQFDLGIASFPEGHFRAKTLEEDTKY
TLAKLRGGAQYSITQMFFDVEDYLRLRDRLVAADPIHGAKPIIPGIMPITSLRSVRRQVE
LSGAQLPSNLEEALVRAANGNEEANKDEIRKVGIEYSTNMAERLIAEGAEDLHFMTLNFT
RATQEVLYNLGMAPAWGAEHGQDAVR
>A0A1I0SIB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus kroppenstedtii|TrEMBL
MHVTDRSRTSRTPSVVDRLAAATHGSVPFSVEFSPPRDQAGEDRLWRTVRAFEQMHPAFV
SMTYGAGGSTRDRTVRVTGDLADSTTLVPVAHLTAVGHSVAELRSMVGAYADRGIANILV
LRGDPPGDPLGPWEKHPDGVEYAEDLVRLVKDLGDFHVGVASFPGGHHRSPSLDDDTRFL
VGKLRAGADYSITQMFWDVEDYLRLRDRVSAFDPEQGAKPIIPEIMPITSMRSIDRAVEL
SGSELPAAVRARLAAAAGTGEEDRAAVRAVGIELATEMGERLIAEGAPGLHFITLNFAKA
TSEVVANLGLARPAPAMTGSATGVESA
>S9RL71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schizosaccharomyces octosporus (strain yFS286)|TrEMBL
MKISDKLQHSDWKDKITWSYEFFPPKTSTGIQNLYNRIDRMKEWGYPMFVDVTWGAGGST
SDLTPVIVNVAQKDFQLDTCMHLTCTNMSGEMIRTALKKAYDTGCRNVLALRGDPPKNET
EWTQAEGGFRYAADLVRYIKKTYGDEICIGVAGYPEGYSPGDDIDRSISHLKEKVDAGAS
FIVTQMFYDADNFIEWVKKCRERGISVPIFPGIMPIQAWDSFIRRAKWSGVKIPQHFMDA
LLPVKDNDDDIRERGAELMVQFCRKLIDNGITRLHFYTMNLEKAVKMIIERLGLLDKELQ
EVTKKPENELTTNRTDIFPNGTKRENEDVRPIFWRTRLESYISRTEQWDEFPHGRWGDSR
SPAFGEFDPSRHGLRQSAPEILALWGSPKSYRELGELFASYCTKVKTSLPWSDMPISEEA
KVIQDQLEYMNTKAFLTINSQPALNGVKSSDPVHGWGPTNGYVYQKPYVEFFVHPSLIDE
IKSSLHQMEDMSYFFISVSGKLDTNAAYEVPNAVTWGVFPNREVIQPTIVESTSFLAWKD
EAYSLGMAWASAHDPKSETHKLLVSMMSSWVLCVIVDNNYERGQSLFDIFPKLRSLEDIH
PELYNGVAI
>A0A2W7L9V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 2848|TrEMBL
MSLLKTTLDANAFACILEFVPKPGAERFATLDTLMARTQLCGWPLTVAIGDRVCSALDMS
PLDAFNSLAEPVPALLHFSGKDRERRDLLAQLQRMDAAGLDQLLLLTGDRLPGHIPGERP
VRYLESVAALQIVRQARPHWLLAAALNPFKYQEAEGGAQYCKAEKKLAAGADLFILQLGF
DIDKHQEAFDWMQRQPRPKPLMACIMALTEGRAGMLEHVAGVTVTPSMRALLAAEAAVSK
TYAKQRANQRLALQVIGLKLMGYAGVHLSGIHEVAQFEALEQAISALQPQFTSLEDWTPA
WEAAWQEADLEPVTFHPPGHAWRLGQRQITASNKEKVRYHLLSAMHHQLFSRTTALSKAF
GWAVTRPLWANPTAAQWLHQLERRIKRPMVGCDTCGSCRLEDTLYICPETCPKGLANGPC
GGTRLDRCEFGDRECVHSAKYRLAVSVGRTEVLRERLIPCVQVENRQRSSWPVWFEAATS
KSPSRQPDVAAEFNE
>A0A850MLD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Helarchaeota archaeon|TrEMBL
MSNRIFSNLMHDIKLGKFVFTGELEPEKTTNLDELFKGVKLLLNHVVACNVTDNPQSMGY
ISSLVASYAVQKETGMEVIYQLRCSDRNRLALLSDLLGAGYLGIKNILALTGDHTSIGDN
SGAKPVFDLDSGQLIYLIRKMVEKGVDLEGNHIENPPKFHVGAAGNPNADPLEPEILKIG
RKVNAGAEFIQTQVIFDIEQAERFLKAVERYRVPVLIGVFPTKSYGVASYFDKYIPGVSV
PQDLLDKLKKVSEISDKKLRKEKYAEENLEFFGDFFNELIKTSAAGIHVMAVGYEKITCK
LIDRVRGKASWIEREQIYK
>A0A7C8JAZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orbilia oligospora|TrEMBL
MQEKITDKIKALPKDATYFSLEFFPPKTPAGLQNLHARLDRMAKGLRPLFVNVTWGAGGS
TATKSLELASLCQSHGLTTVLHLTCTNMSKSVLDDALENAKLMGIRNVLALRGDEPRQHE
YLDVTEQVRNGSGENEFVYAIDLVRYIRKQYGEYFAIGVAAYPEGYAETAYPVAQDTARD
LPYLREKTAAGADFIMTQFFYDVEAYISFEKVLRDDESGVFKDIPIIPGLMPVQSYQIFR
RTTKLCSVKVPGTISSRIESVKADDEMVKEHGIQVLTEMIGKIRSSTESDGGLPRGFHFY
TLNLEKAVAFIVERCNLIPEIPTSNEVAVEDEDDEGPGLLTVNGGGAAIPRRSRRTSSII
SDPHNRVIVDTVSSARSELQAEAGEAGVPKILDPGSQEGNLAISEGEGSLGREATWDDFP
NGRWGDARSPDGYGVSLHRTPTEALKLWGKPTSTKDISDLFVKNSKGELEAMPWSEDILN
PESFLITEELVKMNAKGWWTVASQPAVNSAKSDHPTFGWGPKNGFVFQKAFVEFFILDEE
WTELKKKLENEGKEDVSFYAGNKAGDFQTNLASDSSLNAVTWGAFPGKEIITPTIIEEVS
FRAWRDEAFDIWSEWQRIYPLSSATSKLLGELKNKLWLVTIIHHDFVNTDGLWKDILGL
>A0A1F2RU10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium RIFCSPLOWO2_02_FULL_61_28|TrEMBL
MNARAQRFLEALQERVFVCDGAMGTMLYAKGIPISQCFEELNLSMPSLVKEVHEAYRKAG
AEILEANTFGGNPVRLASYGLREKCREINRAGARLARECAGEEGLVAGAVGPVGVRLEPL
GPCSRTEAREAFQEQIEALADAGVDLIQFETFYDLDEIQEAIAAARAVCDLPLLAQVTID
DDGNMLSGTNPEDFTRKLLETGADAIGLNCSVGPKVMLETLQRMAPLSTRPLTAQPNAGL
PMNIAGRNIYLCSPEYMAGYTGPFIRSGVKLVGGCCGTTPEHIRAVRDAVRVAQPPRPRV
ALSAVAPAAPAASRAAGLDPVPLAERSRLARKIAQGEFVVLAEIQPPRGCDPAKEIEGAS
YLAANGIDAVYVPDVHRVSARMSAQAVAQLIQNQAGIEAVLQYSCRDRNLVSIQSDLLGA
YVLGIRNVALITGEPSKKGNFPDATAVFDVDSIGLTKIVANLNRGLDIGGNFLGNQTGFL
IAVLGNPTAADLDQEWERLEAKLRLGAECVVTLPVYDLEKLDRFLERLQPWRMPVLGTVY
PLTSYRNAEFLANEEQVAIPNSILKRMKEAESGEAARAEGIRIAQELVHQLRDRVQGLRV
TAPLGRYGTVVEVLQTLGPKDEAAPRSDARGSA
>A0A4U0Y242|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomyces minteri|TrEMBL
MPRYIDSMHISEKLAEAQKAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPSFIDVTW
GAGGRLSHLTSEMVKVAQSAYGLETCMHLTCTDMEKSKIDGALKEAYSAGCTNILALRGD
PPRDNEKWEATAGGFRYAKDLVKYIKDTYGNHFDIGVAGYPEGCDDQDDLDLLIDHLKEK
VDAGGTFVVTQMFYDVDIFLDWVKKCRAKGINVPIIPGIMPIHTHAAFMRRANWTKCNIP
PAWTKALDPVKNDDAAVREVGKGLVAEMCRKMLDNGIIHLHFYTMNLAQATRMVLEELNL
TPATGSPLEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSP
AFGELDTYGIGLKGTNEQNIKLWGEPASVKDIANLFVRYMQNKLESLPWSEAPISNEADV
IKHDLVSLNERGLLTINSQPAVDGAKSSHPVYGWGPRNGRVYQKAYLEVLVAPDLLPKLL
DRLERDSDFTYYAVNLSGDLKSNAPSDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEF
FRLGQDWARCYPAASPSRQLIDDLMNKWYLVNIVHNDFRQSHGIFPLFEGLNIEHVSKAP
ATNGTTHESGVTSHEEAATNGGADGTSPADATTQTWLGAES
>F0HZE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis SK72|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANELQIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>D6XAA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sviceus ATCC 29083|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPMADWVAHPQGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDSDVTRFVD
KCRAGADYAITQMFFQPESYLRLRDRVHAAGCATPVIPEVMPVTSVRMLERLPQLSNASI
PSVLKERILTAKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHRPQA
>A0A3B6VS57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira pilosicoli P43/6/78|TrEMBL
MNNNVENFIKKLENNNEYCFTLEISPQAKYDLSYIEEKINNSQIQNYADAFVVTDSPFAN
IKISPILAAIQLQQRLNNNKPFIATQTMRDKNSLALQNDLIGANYFDIRMILAVTGDAIA
NGNQKQAKGVFEGNSNLLIDIIKNLNKSKSLGEFTFKEPLKPIYPFCVINSYAKNDDSLK
VRLAKKANSGVKAIFTQPIYEVERLEFLLKCIDELPLKEKPILVPGFFPVLTYKTAYFIY
YKLSGSYIPEKWLSKLKKASDKSEEEERKTAIELSSKLFEDMLKIHKKMHIMSLNNYEFV
VDLLKNI
>A0A3G6J512|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium choanae|TrEMBL
MLRAHQYCPARTFADTAPGGSAAAETDDTCVHPPQSLLQGKVAFSFEVMPPRDLTAAPKF
WATLEQLVASRPDFISVTYGAAGQDRRGAREVTHSIAFDSPTVPIAHFTCVGTSVDEVRQ
ITNDYLDSGVRTFLALRGDPPANRPDWQPADDALTCAADLVRLIRQEEFSRCAEHPSQAL
RASLRPLRIGVAAFPDGNPAAGTTVAQEVERLVHKQVAGADFAITQTVWSADTYATFVRE
ARAKGVTIPIIPGILPPVEARRLHRVHELTGVPIPERLLADLSAAPDSAAAATVGYNFAG
KLIVDLIAEGAPGIHLYTFNQAEPALRTLDRATELLTEN
>A0A1M6VKD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis flavescens|TrEMBL
MAAPTRPVAPRAPAPRARHIRDLLRAGEPMFSFEFFPPRTPAAQERLWLAIRQLEALGPD
FVSVTYGAGGGTRGMTVETTERIAADTTLLPVAHMTLVDHSVAELRHLVGRLADAGVSNM
LAVRGDPPGDPSGPWTDHPEGLSYAEELVRLIKDSGDFCVGVAAFPYKHPRSADVETDTD
HFVRKCDAGADYAITQMFFDPEDYLRLRDRVAARGCEVPIIPEVFPVVRASFIPRSEKLS
GAPFPAALAERIHSFGDDADAVRAFGIEHAQKMCERLLDEGAPGIHFITSNQSTATREIY
REVSGRLNR
>A0A427Y288|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saitozyma podzolica|TrEMBL
MVHLTSLIAAHQGPFHTYEFFPLAQTRVSSTSSTVSADFAPRPSPLRWPSDRTLGLAEEV
VKLGVEVILHLTCTNMPKAKVDQALSKAKELGIQNILALRGDQPRSAEYATTPNPEPDFF
THADDLVRYIRAEHGSYFCIGVAGYPTPHPDSESAETEMHWLKVKCDAGADFIVTQLFYD
VPHFAEWVKDCRAKGITQPIIPGVMPIQSFSSFRRLVNLTKVPVPDSIMADLEPIRSDDA
AVKRYGAQLATNMVRRLLASGVVPGVHFCTLNLEKSVRTILENLDWKSPTPNARQSSPLP
RHNQLIDIDDDGAHSHGQLAAVPQEFSGMSISPAKASQLAEWGLTHSALPPAPKKSTGAP
SGAPGQGEDSWDEYPNGRFTDVRSPAYGEIDGWGSGLKITLTRTPQAAQALKDWGTPTTP
ADLSNLFTAYLRALPSTPTTPFCDLPLSPESTTILPHLLALNSADMQHWTVGSQPAVDSA
RSDDAVHGWGPTGGYVFQKAFVEFFVPAQEVERLEERLKRTNNEQISMYAANKEGDFKTN
TLKDAVNAVTWGVFPGQEIVQSTIIEETSFLAWKEEAFDIWSEWSLLYPRSSPARKLLEG
IASDWWLVSLIHHDYKDTGALWRFLLEEKEA
>A0A5C3ELX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ustilago trichophora|TrEMBL
MANGIDATTLPPKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMAD
LGPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFG
CRNILALRGDPPAGQSEWEPHAAGFTRAKELVEYIREQYGDYFAIAVAGFPEGHPEAIDG
PEKELERLKDKIDAGADFIFTQMFYDFDIFAKWVKDVRAAGITCPIIPGVMPIQTYGGFQ
RATARFGTLVPQYFHDALDPVKDDDMKVREIGTRLVGDMCKKIVGTGLGISGLHIYTMNL
EKGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRRDEKIRPIFWANRAKSYVNRTETWDEF
PNGRWGDARSPAYGDVDAYGVKLRYSNEEAKEMWGTPTSLQDVKALFQKFCAGQVKALPW
SETPVARETSVISEKLTKMNQLGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEF
FVSPEDLDALIARIEADPQITYHAVNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVE
SISFLAWKDEAYEIGRNWAKVYEPTSPSRKFLEDMFNKYFLVNVVHNDFKAADSIFEPFL
STPTASSSVNGSLSGIGSSVADAAGRIANSISSLANGVSNGNTSASAPAA
>A0A7W6BI81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium jiangsuense|TrEMBL
MNAQSCTLLETPVFSDAPLYADMSGDAEVSFEFFPPRSEKVEEQLWQSITTLAPLGPRFV
SVTYGAGGTTRERTHATVERIARETAIPAAAHLTCVGASKSEIAEVAHAYWEAGIRHIVA
LRGDPPQQGSRFEPHPQGYANAAELVAGLKALHDFEISVAAYPEVHPDALSAQADMDNLK
RKIDAGATRAITQFFFAPDTYFRFLDKARAAGIEADILPGIMPVTNFSGVKKMAALCNTE
VPGWMERLFEGLDDQPGARQLIAATLTAELCRKLYAGGVRGFHFYTLNRAELSYAICHLL
GLRARKEVQA
>A0A7C4RTG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatirhabdium butyrativorans|TrEMBL
MNTKAGSRLEQVLKAGEFAVTVEVGPPRGPNAGAVIDKARLLTGVADGYNVTDNQTAVVR
MSSIAASKILLDEGLEPVMQMVCRDRNRIAMQSDLLGASALGIRNVLCLSGDHQKASASG
KLKGHPGAKNVYDIDSIQLVSMVAGMRDRAVQEGGDPLTEPTPFWIGAAWTPLAPPTDFR
VFRLAKKVQAGADFIQTQAIFDLRAFAHAMQQAVELGITERTFILGGVIVPKSAAMLRYM
QRNVPGVVVPEALIDRMSQAKDPLQEGVAITLELIAGLRAIPGVKGVHLQAIEAEHLLPE
ILHAVGLLPRPMGI
>A0A7W8FF89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio intestinalis|TrEMBL
MHIGESIRAAKKPFFSLEFFPPADEANLPGFFNTVEQLQVLAPLFASVTYGAGGGKQRNT
LAVTAELARRGLNTMAHLTCVGADPEKISAFLAELRASGVDNVLALRGDPPVGEDWDWSK
GHFHHASDLVAFARRQQPDMGIGVAAYPAPHPESTSIAQDRLHTAEKMRSGADFAVTQLF
FDSREYLDLLEHLRGRGIHTPIIPAILPIQSFDSLRRVLSLCGANIPGKLYLDLEKANEK
GGAEAVREVGLEFAVRQIQFLLENGAPGVHLYTLNKADMCLRLAEESGLLRA
>A0A7C4VSL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatirhabdium butyrativorans|TrEMBL
MQRRFPASGSRCGLHLPTRHRPNRRIIEEERMLRVFRNDMMDPERFVITLELIPGREHIG
KSVETVIAIARDAFADGRVSAVTMTDNPGGNPALSPDGIGSKIFELGMDVIVHFTCRDTN
RVGMESRALQLAMMGMKNILALTGDYAGKGFAGQGAPVFDLDSVSLQCLLAMLSERINAS
GDPDGFFTGCAVSPFKYTEAESFAQYAKLSRKLCGGADFIITQLGYDARKYRELLVYLDT
IGVHPPVLGSVYILTPKVARLMNAGKVPGAVVPDKLLQKVLREWEHPERGRQAAIERTAR
LGVVLKGLGYKGIHIGGVHTSFGIVTRILDRMAQIENEWPSFVDDISDAPENGFYAVSPD
GHWTGYPDRKGKRLGPFECLHYHLLKGVHEVFFDTTSPIDGPLRAASRWIDERRAARKVL
HLAENVGKYVMLDCRQCGDCAIQHVGFQCPESGCPKHTRNGACGGSRNGRCEVHPERWCI
WRQAYRRFAYDGKLAEMIDGCIPPRNWELDRTSSWLNFHLGRDHQNGSADFERYCCSRRG
WKKA
>A0A258YF87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriia bacterium 24-36-13|TrEMBL
ADGTFEKVEVRKRPGTVGICAAIMNHYRIDTVPHFICGGFNKRESEDALIDLNFLGIDNV
LVLRGDAAKNEASFEPEADGHKYAIDLQKQVVNLNSGIYLDEDIQNGGKTNFCIGTAGYP
EKHFEAPNLEIDLQRLKEKVDAGADYIMTQMFFDNQKFYDYVKACRDMGITVPIIPGLKP
ITNKKQLSVLPRIFHVDIPTDLSNAISKCKTDADCEQVGTEWLIQQSKELKAFGVPVLHY
YTLGKPKVIWNVVKEIV
>A0A0Q0XJD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. SD340|TrEMBL
MIAANAQGTGFPVSFEFFPPKTPEGADKLRAARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPEADLNAYIAKVQAGADSAITQYFYNSD
AYFRFVEDTQRLGANVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSTATLEICRRLGI
>A0A0Q6U4M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. Root342|TrEMBL
MTLPPTHRVIGPVARAGERGQSQAGGRPRVSFEFFPPKTPQMEENLWQAITRLAPLDPAF
VSVTYGAGGSTRERTHRTVKRILDETRLKPAAHLTCVGASRDEVDEVIREYWETGVRHIV
SLRGDPPPGEGGIGGGYVPRADGYANATELTRAVRGVAPFEVLVGVYPEKHPESPSIAHD
IDVLRQKVEAGATLGISQFFFDLDAFLRYVDKVRAAGITIPIVPGIMPVTNFNGLKKMAA
ACGTAIPSWLANLFDGLEDDAETRRLIACSVAAEMCAKLQEQGFEDFHFYTLNRADLVYA
ICRVLGVRETVPATAEAAA
>A0A0Q7GYR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. Root434|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAARQQLYVRKPQFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGMGGEFLYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFATKVKAGADSAITQYFFSPEAYFRFVDD
VRKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWVRLRLQGFGDDTASIKAFGLDVV
TDLCARLQEGGAPALHFYTMNQSAATLAVLERLD
>A0A1Q6HI11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. AG:487_50_53|TrEMBL
MKIKEMLSRTDRRTFSFEVLPPLKGTGTGSLFSTIEKLKEFAPAYINITTHHSEYVYRET
GGGLFERRRIRRRPGTIAVAAAIKNRFGIPVIPHVICSGATIEDIEYELLDLQFLGIDNL
LLLRGDKAKEDRNFIPTPNGHAHTTDLIRQVNMFNNGFFADGTPIKCPMGTFDYGVAAYP
EKHEEAPNIEMDMKWLKAKQELGAQYAVTQLFYDNSKYFEFVRKARAMGIHIPIIPGIKP
FTKVSQLTAVPRTFRCDLPQELALEAVRCKSDDDARALGIEWTTTQCRELYAAGVTNIHF
YTMSASDSVREIVSNIL
>A0A1X7Q8U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum lipoferum|TrEMBL
MTATPSVSFEFFPPKTEKMEQSLWQSIQRLAPLAPSFVSVTYGAGGSTRERTHATVTRIQ
AETGIPAAAHFTCVGATRDEIDSIARSYWDAGIRHLVALRGDPPETAGGVGGRYEPFPGG
YAYAADLVAGMKRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQFFFDN
DAYFRFLDRCAAAGIHVPVVPGILPITNFARAVEFAGKCGASMPAKLAATFEGLDADPET
RQLVAATVAAEQCQALQAQGISDFHFYTLNRSDLTIAICRMLGVKAKAATPAPVAG
>A0A2T4JYG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cereibacter changlensis JA139|TrEMBL
MTQPRISFEFFPPQTLDASFRLWETVQMLAPLKPSFASVTYGAGGTTRKLTHEAVTTIGK
NYGLNVAAHLTCVDATRAETLEIAAAYAEAGVTEIVALRGDAPKGAERFTAHPEGFANSI
ELIEALAATGKFTLRVGAYPEPHPEAADPLADVRWLKRKIDAGASSAITQFFFEAETFLR
FRDACVAEGITAPIIPGILPIENWGGVKKFAQRCGTAVPQWLDDAFDHAKRDGREDLLSV
ALCTELCDTLLSEGVEDLHFYTLNRPHLTREVCHALGVVPEVALQNVA
>A0A329TVJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MTDIREHLAHKPLLFDGGMGTYYKAAPGADCEMANLTDPEGVKKVHAEYLAAGAQAIKTN
TFGLPRMAAAQTPGWEELAEAGWKLACDAAAEKDAAVFADFGPAPDTEAAPASSAYGLVA
QQFAALGAKNFLFETLSSDVGIVEAVKALRVAVPDAFVMVSFAVLPDGYTREGLLFRDLL
RRMEQSGVVDAVGLNCVSAPGAMKKLVQSLGETLLPLSVMPNAGYPVVTRARVLYQGKPA
YFAREMGQIAAAGVRILGGCCGTTPAHIAALRAELDALPQQTEAAPAAKLSTRTAPAVEK
DDAFLRKLNAGEKVIAIELDSPRVADLGGYLDGARRLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGMCALPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSAMTVLGALNLNARNFDVELRRAVEKLENGMSGFL
TQPVLSAQAVENLRKARQTLGERAKILAGIMPVVSQRNAIFMENEINGIHVDEDIIQRFA
GLDREQGEALGLEVSMQMAREALPYADGFYLMTPFNRVALMERLIARLKTELLDAEG
>A0A6A5ENN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perca fluviatilis|TrEMBL
MVNQVQRVDGSWQSCKSDSSGASNNNSGGESSKESSRCSTPVLDVDRSDRLRDKMRRRME
SGDRWFSLEFFPPRTASGAVNLISRFDRMGTGGPLFIDITWHPAGDPGSDKETSSLMIAS
TAVNYCGLESILHLTCCNQTKEKISGHLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNY
ATDLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRAD
TFLKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAI
RNYGIKQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAH
PKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSK
DALLKMWGDELMSEESVYEVFTCYITAQPNRSGHKVMCLPWNDEPLAPETNLLKDELEKV
NRRGVLTINSQPNINGKPSTDPIAGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEP
RVNYHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQ
WAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWQVIDDMFELLDAAPETLHDAP
ETLHAAPETLDAAPETLDAAPETLHAAPETLHDAPETLHAAPETLHDAPETLHAAPETLH
DAPETLHDAPETLHAAAAPEPVKDGAASK
>A0A7Y6HI30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CAI 127|TrEMBL
MALGTASTRTDHARTVREMLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A2A7B0N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MLDVRKLLAQRPLLFDGGMGTYYKTKPGQECEQANLTDPEGIMAVHRAYLAAGADAIKTN
TFSLPRLAAAQQPGWEQLADAGWQLAAKAAGETGAAVFADLGPAPDTESNPAEQVYLAVA
KRFALLGARNFLFETLSAEDGVLEAIRALKRTVPEAFVLVSFAVLPDGYTREGRYCAELV
RRMAQSGVVDAVGLNCVSAPGAMRALVQQLGDAGLPLSVMPNAGYPVVARAQVRYQGKPE
YFARELSRLASEGVRILGGCCGTTPQHIAALRTALDALPETLPAAPAAKPAEAAKPVVEM
DDAFLRKLRAGQRVIAVELDSPKDADLTAYLEGARRLQAAGADLLTIADCPIARARMDSS
LVACREHRELGMNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEAK
NVYQFNSRKLAQYIVSLAGEGREMPSPITVFGALNLNARNFEVELRRAAEKLENGMSGFL
TQPVLSAQAVENLKKARETLGERAKILAGILPVVSQRNAIFMENEVNGIHVDEAIIQKFE
GLDRAAGEELGLEVSVQAAKAAAPYADGFYLMTPFNRVALMERLIARLRTEVTD
>A0A6C1W0A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus licheniformis|TrEMBL
MGLDTLGLSDVLAITGDPSKIGDFPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKT
NFSVAAAFNPNVRHIDKAVKRLEKKIACGADYFISQPVYSEEQLIKIHEETRHLETPIYI
GVMPLTSSRNAEFIHNEIPGIKLSDSIREKMALAGNDKQKQAEEGLAIARSLLDAACDLF
NGIYLITPFLRSDLTAELTAYIHQKEKEKTNV
>A0A8D3DDJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scophthalmus maximus|TrEMBL
VVDEHVQHYTGEGSWSDSSGASNSGGESSKESSRSSTPVLDADRSDRLRDKMRRRMESAD
RWFSLEFFPPRTTSGAVNLLSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQTREIITGHLAKAKHLGLKNIMALRGDPVGADWEEEDGGFNYAID
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVITQLFFRSDTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITNVIEPIKDNDAAIRNY
GIHQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LHMWGEELMKEESVFEVFTCYITAQPNCSGQKVMCLPWNDEPLAPETNLMKDELEKVNRR
GVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVHGRNLTNALDFQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIEDMFEMLDAPPEPV
>A0A8H8D914|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces capsulatus|TrEMBL
MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTWAVDLVKYIRRTHGDYFCIGVAAYPEGHSDESYPEVQDPVKDLPYL
IEKTRAGADFIMTQLTYDLGAYKRFEEMLRNHESGVFETIPIITGLMPIQSYHILTRTTK
LSHARVPPDIMARVEAVKSDDEEVKRIGVDILCEIVNGLKQVSYPGPRGFHFYTLNLEKA
VALTVEKCNLIPPLSPLPSDSETYMDTAVFMAQGKQNGISLLSKRRASSMNSQPHNRLIV
DRPSDAGGSSQASTTHETPALGAGMPALNPPPRTTTLQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVNAAVARRLWGYPTTKQDINNIFQRHVSGELHLVPWSEGGA
QDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAF
VEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSSPATDATTEDSSGPVDVFLD
SNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIFPRGSPTER
LLDQLKNDVWLICCVGQKYGAGCASLEAAEAEGKLLWKLLGGTGTGPDSVNNH
>A0A2A7B9F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MNDIREFLSRRPLLFDGGMGTYYKAAPGIECERANQTDPAGVQAVHREYLEAGADAIKTN
TFGLPRMAAAHTPGWEALAEAGWKLAEAAAAPAGAFVFADLGPAPETEALPAAQVYTAVA
EQFRKLGAKNFLFETLSSDAGILEAVRTLKAAEPDAFVLVSFAVLPDGYTREGLYCKDLV
RRMSESGCVDAVGLNCVSAPGAMRTLARSLSSALPLSVMPNAGYPVVTRTQVRYQGKPEY
FAQELSGLAADGVVRILGGCCGTTPAHIAALRAALDALPETAAPARTKEFSTPEAKPVEN
EDAFLRKLNAGEKVIAIELDSPRNADLTAYLEGARKLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGMCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSAMTVFGALNLNARNFEVELRRAGEKLEHGMSGFL
TQPVLSGQAVENLRHAREVLGSRARILAGIMPVVSQRNAIFMENEINGIHVEEDIIRQFA
GLDRAQGEELGLAISLKMAREALPYADGFYLMTPFNRVALMERLIARLRTEVLQES
>A0A414A4J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MLDVRKLLAQRPLLFDGGMGTYYKAKPGQECEQANLTDPEGILAVHRAYLAAGADAIKTN
TFSLPRLAAAQQPGWEQLADAGWQLAAKAAGETGAAVFADLGPAPDTENLPAEQVYLAVA
KRFALLGARNFLFETLSAEDGVLEAIRALKQTVPEAFVLVSFAVLPDGYTREGRYCAELV
RRVAQSGVVDAVGLNCVSAPGAMRALVQQLGDAGLPLSVMPNAGYPVVARAQVRYQGKPE
YFARELSRLASEGVRILGGCCGTTPQHIAALRTALDALPKTLPAAPAAKPAAAAKPAVET
DDAFLRKLRIGQRVIAVELDSPKDADLTAYLEGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGMNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPAPITVFGALNLNARNFEVELRRAAEKLENGMSGFL
TQPVLSAQAVENLKKARETLGERAKILAGILPVVSQRNAIFMENEVNGIHVDDAIIQRFE
GLDRAAGEELGLEVSVQAAKAAAPYADGFYLMTPFNRVALMERLIARLRTEVTG
>A0A2N1W1F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Goldbacteria bacterium HGW-Goldbacteria-1|TrEMBL
MKISEILKNKEFVFSMEIFPPKPDSDISVIYNTLDGLKDLKPDFISITFGAGGGTRSRTV
EIAERIENHYKIPCMAHLTCIGATKDSITGILNELQSKNIQNIMALRGDLPEGVKDPLKD
FKYASDLVKFIKNKWDFCVGVAGYPEKHPEAKDIKVDIENLKNKVEAGASFITTQLFLND
DHYFNFVKLAREAGIKVPVLPGIMTATKISSLERMTKMCGVEIPERFKIATSTCAIDNPV
CDETVKYTVGQINHLIKNGVPGIHLYTMNRVEQNRHIYNESDISKLRNGNV
>A0A286TF22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum LMG 13195|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIANTIH
GEYGIPAVAHLTALYSDEAKIDEALDMFEAAGVSAVLALRGDYIDGEEPVGRFNHASDLA
AYIHDRKPDLKVFGACYPEGHYSAASLDEDIENLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGGKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGII
YASDQIADLVAHGVDGVHLYSMNHPATTRRIWHNVEPLFTVE
>A0A3S2WQG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium CCMM004|TrEMBL
MPAPHLSFEFFPPQSLEASFRLWETVQTLAPLKPDFVSVTYGAGGTTRDLTHEAVTTIGK
ATGLNVAAHLTCVNATRDETLAIARSYAEAGVREIVALRGDPPKGQGQFQAHPDGFADSC
ELISALKGLGAFHIRVGAYPDPHPEAANGDADIDWLKRKVDAGADSAITQFFFESETFLR
FRDRAAGAGISIAILPGILPIENWTGVRKFAARCGARVPAWLDDAFAVAQRDGREELLAT
VLATELCSELLDGGVEHLHFYTLNKPQLTRDVAHALGIVPEPALENVA
>A0A416ZEA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF08-23|TrEMBL
MYISDIFETAQRLRRLPVSFEMFPPKGELTLERAREVAASFAPLGPDFISVTYSAGGSGN
NAATTQIAQMIDTELAIPSVAHLTCISLKRADLAAKIDEMRAAGVENVLALRGDVPEGAP
TGPGCADFRYAKDIIPPLVEAGFCVGAAAYPEGHLECDDLARSMRHLKQKQDAGASFFVT
QLFFDNDYFYRFRELADSAGITVPITAGIMPFMGKQQISRMVFMCGASLPSPVIKLLARF
EDDPDSLRAAGIEYACRQLEDLADHGVDGLHIYTMNRPSVARAAMSALRQETR
>C7Q4A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)|TrEMBL
MPDHDFDLICEIEPPTRPDLKRVRHQIGVMSPIADSFLIPDNHIGRATVSSVAVAHEVQA
MGASGIACLNSRDRNVLGLQRDLLTAAAYGVRRFLFVYGDKPTSGGRTSDLTVRTMIEQS
RAAAQDPRFQGAGQFQVGVATGLRPIPTWKHEADFAFAQVSFSLEALIRWRESITLDIPI
FAGVMVLASPTMARNLAASIPDIDIPDALVQAVDQDPQAGVEAACDQVLAIRATGAFAGV
HLVPVSRYRQVAARLEAVL
>B2ZZ98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilus methylotrophus|TrEMBL
MNNNISYSFEFFPPKTVEGMANLRNVRNELAAFSPEFFSVTFGAGGSTRDRTMESVLEIQ
AEGHGAAPHISCISSSKEEIRELLQAYQAKGIKRLVTLRGDIPSGEVSAGDFKYANELVS
FIRAETGDWFHLEVAAYPEFHPEAGSAQKDLENFKRKIDAGADSAITQYFYNMDAYFRFV
EAAQKMGVTAPIIPGIMPIYNYTQLARFSNVCGAEIPRWLRLRLEAYGDDLASLRAFGVD
VVTDICAKLIASGVDKMHFYTLNQAGIIGQIIRQL
>A0A2E2IRB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacteraceae bacterium|TrEMBL
MTPTLDQLHEARTALEAPLFSDLPGDIDISFEFFPPKTEKMAETLWDSVATLGPLGPRFV
SVTYGAGGTTRERTHEQVVRIQNEAGIPAAAHLTCVNATKEEVNEVARHYWEEGIRHIVA
LRGDPPEGASAYTPHPGGYENAADLIAGLKKVADFEISVAAYPEVHPDSPDAQADIENLK
AKFDAGADRAITQFFFDPECFFRFRDEAAAAGIDAEIVPGVMPVMSFAAVQRMSGMCGTA
IPAWMEGLFEGLDERPAARQLVSATIAAELCRKLYAGGVRQFHFYTLNRAELSYAICHML
GKRPAGDAK
>A0A1G7AYW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kordiimonas lacus|TrEMBL
MAQRYNPHGLNSLFEEAVSDVNVSFEFFPPKTPKMEETLWNSIKTLEELNPKFVSVTYGA
GGSTRERTHNTVKRIVEETSLAPAAHLTCVGATRDEIDEVVREYYQAGVRSIVALRGDPP
EGANRYEAHPGGYANAAELVEGIRKIGDFDISVAAYPEKHPDSATLAADLDNLKRKVDAG
ANRAITQFFFEPDQYFRFLDHCDSYGINVPIVPGILPVTNYATLKNFAATAGASVPKWLG
DLFDGLDDKPQTRSLVAATVAGEMVRRLYAGGVRDFHFYTLNRAELTYAICHMLGIRAGK
EG
>A0A2W7IV78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. URMO17WK12:I2|TrEMBL
MSQKRANVSFEFFPTKTDAGHEKLLNTARELAGYNPDFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDSKAELIELLNLYKSKGINRIVALRGDLPSGMGMSSGELRHAND
LVELIRQETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGANSAITQYFFNPDCYF
YFVERVRRMGVDIPVIPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDTQSIQRF
GEEMITAMCERLIEGGAPSLHFYTLNQAAPSLAVWKNLQG
>A0A3A9ABM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium 1xD42-87|TrEMBL
MSKRTSLSFEVFPPKKEEEFENIFEFLREAAKLHPDFISCTYGAGGSRAGKTIEIASFIQ
KELGINAIAHITCVGFTKADLEKNCEALEAAGVNHVLALRGDRPQHMTDEQFNSREFFYA
TDLVRHLKAHTSLLISGACYPEKHFESPTLEEDLAHLKEKVDAGVTSLVTQMFFDNACFY
RFIELVRAKGITVPIHAGIMPITTAKQLGTTVSLSGSSVPKELADMIATYGENKEDMRKA
GIDYAVRQILDLKEHGVDGIHIYSMNKLKTTTEICGLIS
>A0A5J6QD72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. C27(2019)|TrEMBL
MSKQPRISFEFFPTKTDAGHEKLLTTAAQLATYNPEFFSCTYGAGGSTRDRTLNTVLQLD
GEIKIPTAPHLSCVGDSKDDLRELLHLYKNAGINRIVALRGDLPSGMGMASGELRYANEL
VEFIRKETGDHFYIEVAAYPEMHPQARDFEIDLQNFARKVRAGSDSAITQYFFNADCYFY
FVERARKLGIDIPIVPGIMPITNYSKLARFSDSCGAELPRWIRKQLEAYGDDTASIQAFG
TEVITNMCERLLDGGAPGLHFYTLNQAEPSLAVWDNLKLNR
>A0A6A6NTS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lineolata rhizophorae|TrEMBL
MHISEKLAEARKNNKATFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFVDVTWGAGGRMS
HLTCEMIKVAQSAYGLETCMHLTCTDMERSKIDEALSAAYAAGCTNILALRGDPPRDKER
WEATQGGFRYARDLVKYIRDRYGDHFDIGVAGYSEGCDDQEDVDLLIEHLKEKVDAGATF
VVTQMFYDVDIFIDWVAKCRKRGITVPVIPGIMPIHTYAAFLRRANWTRCRIPPEWMEAL
EPVKNDDAAVREVGKGLIATMCRRLLEAGILHLHFYTMNLAQATRMVLEELNLLPDLEAP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNRKLWGEPRSVRDVAQLFVRYCEGELASLPWSEAAITREADSIRGDLVA
LNRRGLLTVNSQPAVDGAPSADPVVGWGPRNGYVYQKQYLEVLVSPELIAELLTRVERDP
DLTYYAVTRSGDLKTNAPGEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGEDW
AKCYPSNHPSRYVIEDLMDSWYLVNIVHNDFHQTHGVFPLFDGLEVKDMDKTYDESIMNG
DHKDAHADASFTATAAPNGVKN
>A0A8D8CR96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Culex pipiens|TrEMBL
MHRQTVESDPNGEEDKSTILAAGAVTAEVMHSHENSRNLKQVIQRWTTSERLCYSIELIP
REDFHLDLGRLAPVFCSLPWISDNNLQYQRFVDTPMLKMTAKIVPRCPVMNHLSCYNITE
TQVDKFVDMGNWNLFVIRGDTVSEGQRFQHSGDLVEYLRAKNNPDLTIGVGGYPYGHPES
PSVDYDVKYLKQKVRCDKQAVCDKRGDIGEFKCSTRSPARRSLVCV
>A0A7C6W9A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MNADTFLFDGAFGTYYAQLTNKFEPCELANLDNRQTVFNIHKSYIDAGVNAIKTNTFGAN
SGLGFDFETVERIIEEGYNIALDAVEGAKAQVFADIGPIPYKDKDQDISQEYIKIADVFL
DLGAQKFLFETMPEFNVLKPVLKHIKKKSPTSYIIVSFASSLDGYTKSGLYYKQLLDKAQ
KDANVDAIGLNCLCGPAHIIELVENYQSKIVKPMSVMPNSGYPENVGNRLVYIDNAEYFA
KKLLKLRKIGITILGGCCGTTPLHIQKSRLILSNFKGEKSHKYNNIAPKEEQKSDYKNIF
YEKLANNLFPIAVELKAPVDTRIDYLINGAKNLLSAGADLITIADSPLSRTRADSFIISS
KIKREVKIDVLPHLTCRDKNIISIKAALLGLNIEGVQNVFVITGDPIIATDRSSIKGVFD
FNSIGLIKYIQSLNQNVFSNSPFLIGAALNTNAVNFDYELKRAQQKMQAGAKFFLTQPIF
GQEGIDRIKKAKDLLNAYILAGIIPPYSYKNAVFLNNEVSGISIPQDLILAMKEAQNQAE
VSFEYAMDIIKHLKPVCDGLYIINQSKKTELVSKIVASAELL
>A0A1W0A7Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thraustotheca clavata|TrEMBL
MGKIIDRLLELEKTSTPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSGFK
DEKLWLKIGAHIQNEFKIDVLMHLTCHLPQEQLRVILNNARQAGIRNILALRGDPPIGAE
RWKPVPGGFSNAVELIRFIRQEHGDYFCIAAAGYSEVHTEAWNNPNLPPSEQVRQLDMMR
LKEKQDAGADFIITQFFFDVDKLIQWIHDCRELGIRIPILP
>A0A8D8CN89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Culex pipiens|TrEMBL
SFVSILSRGSVSFGGLSFARNLSADVLVWWLSSSRDLLRTTRGTRVTVEKRTEKRLRGLN
LSSPSREKRRPPPTSPMHRQTVESDPNGEEDKSTILAAGAVTAEVMHSHENSRNLKQVIQ
RWTTSERLCYSIELIPREDFHLDLGRLAPVFCSLPWISDNNLQYQRFVDTPMLKMTAKIV
PRCPVMNHLSCYNITETQVDKFVDMGNWNLFVIRGDTVSEGQRFQHSGDLVEYLRAKNNP
DLTIGVGGYPYGHPESPSVDYDVKYLKQKVRCDKQAVCDKRGDIGEFKCSTRSPARRSLV
CV
>A0A367JZM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus stolonifer|TrEMBL
MGVQNLYDRMERMQRYGPEFIDVTWGAGGTSADLTMDIVTTAQSVYGLETMMHLTCTNMP
AEQIDKALEATCGCQNILALRGDPPKGQLNWESCENGFSHAIDL
>A0A316NFF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MAENTLLYLFDGAMGTYLSDRYGTEISRSEFNNLKYPERVFSVHREYIEAGATAIKTNTF
SANTASLGVSRKEADEIIARGCAIALKAAQGTNATVFASIGPVSMQQEEREWEEYCSIIM
TVLQSGVRHFLFETFHEYRVLLRLADEVKRCCPEAYIIAECTVTADGYTTSGIPAAEIVA
ALRGADAVDAYGFNCTCGPMHLLHIAQRMDIGPKPVSIMPNAGYPTLIGGRTVFENAPAY
FAGQMAAIQQSGVRILGGCCGTTPEHIRITADALNGKRLELDRKKKGTVSVQGGKSPLKP
ATERPQTASGGKRFAVELDSPMDANPEKFVQAARDIWDKGVNMLTIADCPVARARVDSSM
LAALLKHRYGIDVMPHLTCRDRNLNATKALLLGLGIESIDKVLVVTGDPIAAEDRGKVKG
VFNFNSEKLIAFIRDLNRGALADCPIQPAAALNVNAVNFEAELERAKRKEQAGAVRFFTQ
PVFTEESCRNLERARAELSAELFGGIMPLVSYRNACFVNNEVSGITIPQETVDRYEGKNR
EQAERLAILLSVQTAKRISAAVDGYYLITPFQRAGLIGSIIDAIKEDFSC
>A0A7V3XAA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidia bacterium|TrEMBL
MKVTEHISRAKDTLISFEILPPLKGKGINAIYDHLDPLMEFKPAYINVTYHRSEHIFKKR
ADGSFEKVVIRKRPGTEAICASIMNRYNVDTVPHLICGGFSIQETEDALLTLSYLGIDNV
LVLRGDAAKNESVFEPEHDGHRYAVDLLKQVVNLNNGIYLEEELKGTNSTKFCIGVAGYP
EKHFEAPNLDTDLRYLKAKVDAGAEYIVTQMFFDNKKYFDFVDRCRKAGITVPIIPGLKA
VTTKKHLTVLPKTFHVDIPDDLAKAVDQCKNDEEVTKLGIEWLIHQSKELKKAGVPVLHY
YTLGKAKVICDVVKAVL
>A0A358Q512|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp|TrEMBL
MENRFKNSILNKNNFSITWELIPGRGAREKSQETAIAAAEKAAKGGKLNALTITDNPGGN
PAMLADYLGQEILKLGIEPLIHFTCKDKNRNQLESQLYALDRAGIRNLLAMTGDYPKTGF
GGRPKPVFDLDSTHLLRLITKMNEGLEVKVPKGSAFHQPSDFFAGAVVSPFKALEAEQMS
QYYKLKKKVASGAQFIVTQVGYDARKFHEVLQFIKLHDLKVPLIGNIFILSFGTAKLMAR
NELPGCVVTDKLVAELDKERTAPDKGLEARLLRAAKMYAFMKGMGFAGVHVGGHNTKYEE
VEYIIDKGEELAPNWHDLIQEFDYPMPDGFYYFRKDEGTGLNSEIPVERDNLPIEAPVGF
QFWSMWQMHKLAFTPDVGLFKTMQRIYTKKHPKRYALEHFVKAVIYDCKDCGDCALLDLA
YLCPMSQCPKYLRNGQCGGSYKGWCEVYPNERQCIYVRVFARLKKYREEEQLDSYHIPPA
NWNLFQTSSWYNYYLGRDHSALTLGITPPQTKG
>A0A7X5C3R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sacheonensis|TrEMBL
MLSEKIRNRETGIITYGMTPPKESHSPDKIAEIAQRQCERLEGLPIDGLILYDVQEESDR
VDLDRPFPYLRTVEPMAYSSEYLSRLNVPKIIYRCVGGHSESELAEWLQADPGQDRFSVF
VGASSSKQAVNLDLPSAYELSRRINPKLAFGGVVIPERHAKKHDEHIRIADKIRRGCGFF
ISQAAYNVEAAKDFLSDYYYYCRDHEIDMVPILINLAPCGSAKTLDFMKWLGISIPKWLE
NDLKYSNDVLDKSITLSHKIFEEIFDFGLEKGIPLGCSVESVSTRKVEIEASVQLVRDIK
STIEKRMRPAIAI
>A0A7C6K0R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MRLKDYLKKYRLIPDGSMGTYYSELVGKPGAISEYANQSEPDIIKQIHKEYLEAGARLLR
TNTFAANRAVLQLGEEQQKSLLSQACYIAKSALEEAGLTPEDRAASWILGDIGPIPEDAG
TNEEDILTEYKLMCDIFIQEGLEGIHFETFSSLHYIEKLLPYIKNKKSDMFILVSFSVNK
NGYTEAGISAARLLDTAGQTGGIDACGLNCGVGSGHLYHILKKLKFPEDRYIYAAPNAGY
PEQMQNRMVFMDNAEYFSDNMELVAGLGVDMIGGCCGTTPAYIKALNLRIKNKERIYPRK
TEAAKTESQSRPHKENDFYQLLLSGKKVIAVELDPPYDADIDRVMECAHILKSSGADLIT
FADSPMGRSRVDSILMSIKIAGETGLKVMPHICCRDRNMISIRSSLLGAYIHGIRNLLIV
TGDPVPSTSRAKTTAVFDYNSVQLMDFVKEMNLEHFASEPLYFGGALNHGRGNLDREIER
MQKKIAAGAAYFLTQPIYSVEDVERIKKIKERVDTKILCGIMPLVSYRNACFIKNEVTGI
RVPEEIVDRYSPDMSKEEAENVGVEIAREMMELLDPVTDGYYFMLPFNRVSLMDKILKK
>M4RFM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium thermophilum RBL67|TrEMBL
MHQPMFSIEVFPPKRNAPVGTIYDTLDGLQGLNPDFISVTYGTGKSSDRTATARIANTIR
KEYDIPAVAHLTAQYTTREQVDEALDMFRQAGVSAVLALRGDPVPDREPAGAFEHASDLV
AYIREHDPDMTIFGACYPECHPQASDLDEDIRNLKIKVDAGASHLISQLFYDNADFYHFL
DKARAAGIDVPIEAGIMPVTNAKQIRRMVRMCSSRVPLPLESLLDKWGDDPKTLKQAGII
YASNQIADLVAHGVDGVHLYSMNKPAVTRQIWHNIEDLFSPGQTGTDFA
>A0A3S1P8G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.005.03.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A401MND1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NL15-2K|TrEMBL
MALGTASTRTDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPQGLAYAAELVELIKNSGDFCVGVAAFPAMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVAAAGCETPIIPEVMPIASVKTLARVPSLTNAAF
PPALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHRPQT
>D7WBR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium genitalium ATCC 33030|TrEMBL
MDPLDEALEQPARTPARTALSFELIPPRHDADEAKLKDLVSGLAAYKPDYIAVTSSRRSG
WLEGTADFIARLTESTNLPTIAHLACTAGTEEELADWIRRLIDSGVRGFLALRGDLPEGE
TSLPEGYLQYATQLLTLIQEIEEENAYRLAAGKLALSVACYPSGHAESPTPDLDLDVLLS
KQRLGADFAITQLFFAAEDYLQFAEQSRMAGVRIPLIPGIMPMTSLKRVERMGVLSGIEV
PQTVVDALSSASTPEEEYEAGMQLTVELTQKLLDAGVGGLHIYTHNNLAVTEDLLSRLGI
EKPTN
>A0A0J6YI68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccidioides immitis RMSCC 2394|TrEMBL
MHVKEKLAHSEASGRPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPPREKES
WAPTEGGFRYAKDLVKYIREKYGNHFDIGVAGYPEGCEDEEDPETLMKHLKEKVDAGGTF
IITQMFYDVDIFLDWVKRCRENGIQVPILPGIMPISTYASFLRRSNWVKCKVPESWMEAL
EPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQATKMVLEELKLIPSYETP
LQKPLPWRQSLGLGRRDEDVRPIFWRHRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSIKDLSAIFIRFLEGGLDRLPWSESPITEETDDIKHDLID
LNNRGFLTINSQPAVNGMSSSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNP
DLTYYAINKNGELKTNTSDSPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRLGDDWA
KCHDARSPSRQLIQRVMDEWYLVNIVNNDFHKTHDIFNLFNDIVVKDLDVEATGIEESTS
QPANTNPERQNGDAAQTKDILVGTNGTSN
>A0A2V2GBN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKVIDIIKGEKPSLSFEVFPPKTSDKLESVEKAVNEIATLNPSYMSVTYGAGGGTSDYTV
RIARELLDKGVTSLAHLTCITSDKSNIKNMLTTLKENGIENILALRGDIPEGFSRENLSY
NYASELVKDIRESGDFCIGGACYPENHPESENSYADIEGLKKKIDAGCEFLTTQMFFDNN
ILYNFLYRIQRAGIFAPVVAGIMPVTNARQIKRIISISANALPQRFIRIVDRYGDNPEAM
KQAGIAYATEQVVDLFANGINAVHIYSMNNPDVARGIKNNISELIK
>A0A3D1XC74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKIKDILSANKPSLSFEVFPPKTETVFDSVKAATEEIAKLRPSFMSVTYGAGGGTSKYTL
DIAKNIKELYGVPTLAHLTCVSSTKESVRQKINEIKAAGITNVMALRGDIPPALEGADRS
GWDYRHAVDLIYELKAADPDFCIGAACYPEIHPESPNQKEDIRYLREKVDAGADFLTTQM
FFDNNLLYNFLYKIREAGITVPVIPGIMPITNANQVQRAIKLSGSFMPQRFKSLVDKFGS
DPAAMKQAGIAYATDQIIDLYANGINNVHVYSMNKPDVAARIHSNLSDILGK
>A0A101F917|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterales bacterium 50_218|TrEMBL
MKGENKLNNLKAGSNLEKVLASGHFACTGEIGPPKSADFHHIDMYAEGMKGKVDAVNFTD
NQTAIVRLASWGAALRLLYKHGMEPTLQVVCRDRNRLAIQSDLLAAYAHGIRNVLCLSGD
HQAFGNHPGCKGVYDVDSIQLISILRKLRDEGRFECGEECKVAPKFFIGCAVNPFADPFE
FRVIRMEKKIRAGADFVQTQCILDMERFEKFMDLVRKEGLHERVYICAGLMPVKSPRMAR
YMQTGVPGMLVSEEFCQRLEKAENPKEEAVNITIDYIKRCQKIEGVHGVHIMAVAWEEIV
PTIVEKAGLLPRPTF
>A0A7C7Y583|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNTAKKRNFSVEFFPPRSEAGKTKLNEVHRKLALLKPDFFSVTYGAGGTTKQGTKEIVLQ
YSNEGSTLVPHLSFGGTEDREILTLLAEYKDAGINRLVALRGDNPSGMGAAIQHRYANEL
VEFIRKETGETFHIEVACYPDIHPESKSYTSDVSHFKNKVSAGANSAITQYFYNPDSYFR
FVDYCAGQGITIPIVPGIMPITNYANLARFSGSCGAEIPQWLDKRLTGFGDDTEGLKSFG
IDVVTRLCEQLLEGGAPGLHFYSMNLASSVNQIWKNLSIKNGG
>A0A847BY26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadaceae bacterium|TrEMBL
MSRLSEQLAAGRFVVTAEIAPPKGVSIDLILEQATAMKEVTAINVTDNQGANMRMSPVAV
AAVLVREGYEPVLQLTCRDRNRLALQSELLGASLLGIENLLLLSGDHPSFGDHPQSRPVF
DLDSIHLLEVVKSLRAGFDMAGKPLCQAPSFFPGAAAVPEGEPFELMFQKYRKKVLAGAR
FFQTQAIFDTVRLERFMEAARLLGVPVLAGILLLKSARMCHFLNDNIPGVRVPRDVIERM
EKASDPLEEGVAIARELVCFARGRCQGVHLMTLGQEKRIPDILANCGKQC
>A0A7H5FAH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae 3502|TrEMBL
MQINYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTY
GANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGD
EPAGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHV
ITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYE
GLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A841L7X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polymorphobacter multimanifer|TrEMBL
MTSNPVSEAERAWNPPLFADVPGDIGVSFEFFPPKTPAMEATLWESFETLKPLAPRFVSV
TYGAGGSTRERTHNTVARIAGSVVPAAAHLTCVDASCDDIAEVAEAYWEAGVRHIVALRG
DPPKGPNGVARFEARPNGYANAAALVAGLKRHRDFEVSVGCYPEVHPEASCAAADMDALK
AKIDAGASRGISQFFFEPETFLRFRDRAAAAGISAEMVPGILPVTNFANLKRMAGPCGTQ
VPDWMARLFEGLDDKPAARQLVAATVAAELCRRLYAGGVRHFHFYTLNRAELAYAICHML
GLRPQLTPTGLEAAA
>A0A2D5T8A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MEQVQAKNNRIASDLENAYMEVIPFPDIEKRFEILKPNSHLAVTCSPTKGVDETLQLCEK
LVDRGFEVTPHIAAKCVEDSAHLESIVKKMEALNISSIFVPGGDRPEPLGKFNNSYQLLN
SLRKLNHNIKSIGIAAHPEGHPDIDEKVLMADLIRKQDLATYVVTQMCFDATILGDWLLK
IKDLGVDLPVWAGLPGVIERGRLLRTSLRIGVGDSLRFLRKKSQVASELMKSSTYHPDDL
VTNIAEYQNINSTNLAGYHIFCFNQIETTEKWRAETIARMS
>A0A6B1AP00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MQFEDEPVTPGDPLPIRPGHSSFGRLERVLRGGGFAVTAEIAPPDSANPAEVYKRAALFD
GYVDAMNATDGSGANCHMSSVGMCSLLTRRGYAMVMQVSARDRNRIAIQGDILGAAAMGV
ASILCLTGDGVDVGDHPQAKPVFDLDCMSMLNMIRHMRDESRFLSGRELTEPPRVFLGAA
ANPFAPPLDYRPHRLAKKVAAGAQFVQTQYCFDIDAFRRYMDAVREAGTHEKVFILAGVG
PLASARSAEWIRGNVPGVHIPDAVIRRLKTARNQQQEGVNICIDMIHQIREIHGVHGIHI
MAYRQEHRVAEIVERSGVLGGRMPWRPAVDWKNAEWDQGHPVATHTPDRQVLESVS
>A0A437PQU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sandaracinomonas limnophila|TrEMBL
MTKITEYFNQAKGKTLFSLEIIPPMKGSNFGDLMQNIEPLMEFNPPFIEVTYHREEYITK
EVNGETKRIPIRKRPGTLGICAAIMQKFKVEAVPHVICGGFTKEETEDFLIDLHYLGIEN
ILALRGDQEKGETHFIPKSGGHAFANELVEQISAMNQGKLLYEETESFPTNFCVGVAGYP
EKHFEAISLEEDLQNLKRKVDAGADYIVTQMFFDNRKYFDFVDKCRAIGINVPIIPGLKP
LSTARQLQILPEIFFLDIPEDLQKAVKACTAPEQIKQVGIEWTIAQGRELMQAGVPALHF
YTMSKSDNVQAIAKSLF
>A0A6B1EHQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MQFEDEPLVPGERLPIRPGHSSFGRLERVLRAGGFAVTAEIAPPDSANPAEVYERAALYD
GYVDAMNATDGSGANCHMSSVGMCSLLCRRGYAMVMQVSARDRNRIAIQGDVLGAAAMGV
ASILCLTGDGVDVGDHPQAKPVFDLDCMSMLSMIRHMRDESRFLSGRKLTEPPPVFLGAA
ANPFAPPLDYRPLRLAKKVEAGAQFVQTQYCFDIDAFKRYMAAVRDAGIHEKVFILAGVG
PLASARSAEWIRANVPGVHIPDAVVRRLKGAVDQQREGVNLCIETIRRIREIEGVHGIHI
MAYRQEHWIAEIVERSGVLEGRRPWQPPLDWQNAAWDQVHPAMPNAQGRQAMEEIS
>A0A6L7LUR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MEISHLSFEFFPPRTEEEFRNLTRSADRLQQENPDFFSVTYGAGGSTKDRTYHTVQKLRN
LGLNTFPHLSWGDSSKLTMLEQVSEYLRLGIEGMVVLRGDLPSGAVGQLSHSAKDLVALI
RQHFGEKLLIFVGCYPEVHPDADTMKTDLRFLKEKVDAGATACITQYFYNVDAYIRFVDE
CQRIGITQAIIPGIMPLYNYHVLVKFSQNCGADIPRWIERRMYEYREDKSALEAFGIDVV
SRLCTRLIESGAPGLHFYTLNRALSVKKILKNLEITTESSNEMTEKK
>A0A7C8CY70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSRLAQALSMSEFVVTSELIPPKGVDLEPLFEKAQALNQVVTAFNLTESHTAKMSMDPVA
VGHLLLDRGVEPIVQMTSRDKNRIAIQASILGAAALGISNIVIMGGDPPQNGDHPDAKGV
FDLYSSQVLDAASALNGGADYMGNPLKGAPAMNIGAVVNPGASDPSAEIDNLHRKIEAGA
GFFQSQAVYDVDALASFLNKADTDAAILAGIIPIKSVRMARFMNDKVPGIDIPETLITEI
EAAGDDPERLAETSIDIAARIIRQIRPLVKGVHIMAIGWEDKIPAIIQRALD
>A0A2Y4XJS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella flexneri|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGICHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>R8YUH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lactucae|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHHYSQQILACIMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYVEQYRHLSLKALEELWNSLWQVT
TGKEFSPEIARFSHPPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENSLVAK
VLIKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKEKLIPTVPIESRGTSSWKNWYLATEA
>A0A2D9MKS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MQEKSENQFSIEFFPPKTISGEAKLDGAFDKLSRLKPHFYSITYGANGSTKKGTQELTFR
YQQMGANIAPHISFGDTSEKDIIGLLQEYKKSGVGRIVALRGDLPKGSDEKLRYASELVE
FIREKTADQFHIDVACYPELHPESDSIKTEVKHFKNKVDAGANSAITQYFYNPXAYFXYR
DYCAQNGINIPIVPGIMPITNYNNLSRFSANCGAEIPRWLRFRLEELSDDKRGLQEYGIE
VVTELCEKLLVGGAPGLHFYSMNLSASVKKIWDNLSLSGKGN
>A0A2E3U4F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDIVNTDARFSFEFFPPRTDVGVEKLEVVHRELAALKPDFFSVTYGAGGSTKDGTRQTVA
RIKQAGSDVAPHLSFGGSSREEIEALLNSYQAMGINRLVALRGDIPSGTGTASQYYYANE
LIEFVRKTTGDHFHIEVACYPEIHPQSDSYDADIGFFKRKVDAGANSAITQYFYNQDAYF
YFLDSCTKAGIDIPIVPGIMPITNFTNLQRFSNSCGAEIPRWIRQRLQAYGDDSASIREF
GIDMVHSLCEDLLAGGAPGLHFYSMNQTEPVRQIWQQLNLR
>A0A6B1HC05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPQFSFEFFPPRSPGGRANLVATAGQLSRCRPQFYSVTYGAGGSTRERTYEAVATLRDAG
INAIPHLSWGGVDADDVIALLHRYLKLGIDRIVALRGDVPSGAGSSHQFRYADALVRLIR
ARIDAPLYIEVAAYPEVHPDAPSASRDIEFLKRKIDAGADGCITQYFYNAEAYFHFRDRC
AAAGVDVPIVPGVMPITNYDTLARFSAKAGVDIPRWLERRLDEIGEHADDLLGFSTDVVS
TLCQRLLTGGAPGLHFYTLNKAPPTEAIAERLVP
>A0A661C7N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
VTLRGDMPSGSAGGYGQLRYANELVEFIRKETGDHFHIEVAAYPEFHPQATNASEDLRNF
KKKVDAGANGAVTQYFYNPDAYFRFVDSCEKLGIDIPIVAGVMPIINCSQLVRFSEACGA
EIPRWILKRLQEFGDDRTAIREFGIDVTTELCDHLLSGGAPGIHFYTMNQSAASEAIWNN
LNLSDIDRNLT
>A0A0V0W637|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella sp. T6|TrEMBL
LMASLEAVVLKATRHDLNSAAKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTTEGL
INLLKRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCILNFCLLDTMLHITSVQY
DEKTVLFNLERAKKIGIRNILALRGDISDDANVTTTDFQYACQLVRFIRSHYGDYFTICV
AEDLLNLKAKVDAGADFIITQLFFNEMHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMK
IVQLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRKLLNREHHVVPGLHFYTLNQ
EKSILEQIGFWKKAPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYLCRTRDWKQFPHS
RWGDVGNPAFGNLKHYLFSCIDQMDDSCALDMWDKELSTLEHVRDIFCNFIARTPNRHGH
SVRRLPWNENHLDPAADVLKNELIYYNSNGILTINCQAAVNGLPSSDPIFGWGEANGYIY
QKGYLEFFASSTCTTILLNHVQNFPSINYHAINFDGSFETFNYDEDATVALTWGVFVGQE
IVQPTVANAASFRVWKVVAQLSFIQFSLHTFGIFLFVFEQDEAFDLWQRWAGLYESRSIG
RKLLQRIHDDYRLITLIDNDYPQPCSLSALLRAVISDYWGKKLDDG
>A0A0B1RNS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. Chr-9|TrEMBL
MDRLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERLGPAFVSMTYGAGGSTRDRTV
RVTGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWEK
HPEGLEYADELVRLVRELGDFHVGVASFPEGHHRSPDLDHDTRYLVQKLRAGAEYSITQM
FFDVEHYLRLRDRVVACDAEQGLKPIIPEIMPITSLRSARRSLELSGSHLPPVLEERLRR
AAGDGPEENRAAVREVGIEVATEMCERLISEGAPCLHFITLNFARATGEVLDRLGYELEA
PAAVQPA
>A0A2D9JPP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSSQMAAKFERGEFLVTSELTPPKGTALESLFAKADMLSTRVDAFNVTDCHGARMAMSPM
AVSHLLLDRGVEPIMQMTSRDRNRLGQQSDLLGAHALGIRNVVFMGGDPPTNGDHPDAKP
VFDLASSELLAAARGLNAGSDYAGNALKGSTDFLVGAVCNPGADDIEAELAKLADKLEGG
ARFFQTQAVYEAESFMRFNERAREMGAYLLAGIIPLKSPKMARFLHDKVPGISIPDHIMT
QVDAASDATATAIEIAASVIRDLKSISSGVHVMAIGWEDHVPAILEAADINARRQPVPPR
SSRRRVATWDV
>A0A534G2H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNAESGRTPIRVSFEFFPPADEAMGAMLWKSIERLAPLAPRFVSVTYGADGSTRERTHNV
VTRIQRETPLTGAPHLTCIGASREEILEIARGYWDEGIRHMVALRGDPPQGEGARRPNPR
GFRYASELVAALAGLAPFDISVAAYPEVHPEASSAAADLENLKRKIDAGATRAITQFFFD
TDAFLRFRDALAAAGVHAPIVPGILPITRFPQVLRFAKACGTSIPGRLHERFAGLDDDHE
TRGMIAASVAIEQVEALRRHGVSEFHFYTLNRAELTYAICHALGLRPHARSASAALQEAR
A
>A0A0Q4CR20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf9|TrEMBL
MTPTISDLEEARRALDAPLFADLAGDCAVSFEFFPPKTEKMEAALWDTVRALEPLAPKFV
SVTYGAGGSTRERTHATVARIARDTSMPAAAHLTCVEASRAEIDQVAQEYWAAGVRHIVA
LRGDPPTMGQKFVAHPDGYENAAALVAGLQKLHPFEISVAAYPECHPDSEHKAADLDNLK
RKIDAGATRAITQFFFTPEAFFRFRDAAAAAGINADLVPGILPVSNVAQVRKFADMCGAS
IPAWMDRLFEGLDDHPGARALVAATVAAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPKATPVAAAA
>A0A2E6YCT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKNFRKALSTQDFVITSEIFLTPETDANSIQMQADILRDYVDAILITDNQSGRVHMSTLA
AGALLIDAGVEPIVQLSCRNRNRISLLSDLLGCTALGITSISLVRGDRVPDDFKPRPKAI
MDVNATELIRIANIMKNDEKIASQGNFFLGGVVTAHAPKPGWPAKNITEKIDAGAQFVFT
HTCLDFDLMRTYMQRLGETKLLWSCHVVAGIVLLSSVDDAQWVSKNRPNVIIPNDIIARL
RDAKNPEQEGIEICAEQLQELSKIPSISGAHVIASEKLTNIPIAISKSGILKKNISN
>A0A502CX04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedococcus bigeumensis|TrEMBL
MVYGPCGGVRLDGECEMIAAPCVFDGLADLPEGSASDWGASGVDRPPEPSGPWQAPLILT
DLSAPPADAQTLRSTARLLAPSCDAVLVGDHQDRADFPPSTLARLIDDADAVPWVTLACR
DRNRISLEQELHALALDGLATVLCVTGDGRAYDVHPEVTQAFDLDGTRLAALAASLGLPV
AVVETPTARPVAVRPKRLVRKQEVGARVAVLNHVPRRAQLVEFLETARVAGLEMPVIASV
VVFTDEVSAAALAGLPGLEIAPERLEAVLTADDPVAAGIATAVNEAVELLELSGVAGVNL
SGLASARGVQDAAEIQAEIGHRIRTTRGVRR
>A0A349SEL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
IEPELSGVWLMSRFAQALSMSEFVVTSELIPPKGVDLEPLFEKAEALNQVVTAFNLTESH
TAKMSMDPVAVGHLLLDRGVEPIVQMTSRDKNRIAIQASILGAAALGISNIVIMGGDSPK
NGDHPEAKGVFDLYSSQMLDAASALNGGADYMGNPLKGAPAMNIGAVVNPGASDPGAEIE
NLHRKIEAGAGFFQSQAVYDVDALASFLHKADTDAVILAGIIPIKSVRMARFMNDKVPGI
NIPEALIAEIEAAGDNPDRLVETSIDIAARIIRQIRPLVKGVHIMAIGWEDKIPAIIQRA
MD
>A0A534BDX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
LVPGILPITRFPQVRRFAERCGASIPRWLHERFAGLDDDQDTCRLIAASVAIEQVEALRR
HGVRDFHFYTLNRAALTYAICHALGLRPLARAAGAARQEALG
>A0A5C7AMD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Seonamhaeicola algicola|TrEMBL
MKVTDHIKNANGKTLFSFEIVTPVKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVE
KDGLLDRKTVRKRPGTLGISVSLKHKYNIDPVPHILCGGFTKEETEYMLVDCHYLEIDNV
VALRGDAMKHQKYFEPTKGGHTYACELVHQISDLNNGKFLHEENLTEFKTDFCIGVAGYP
EKHMEAPSLQTDLKRLKAKVDAGADYVVTQMFFDNQKYFDFVKMAKEAGINIPIIPGIKP
LAVNRHLQLLPHVFSIDLPEDLINAVDNCKNNAAVRQVGIEWAIQQSKELKEAGVPVLHY
YSMGKSDNVQAIAQALF
>A0A349UW92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
GAVYQRASVFDGCVDAINATDGSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQ
GDVLGAAAMGVTNILCLTGDGVQAGDQPDAKPVFDFDCISLLQTVTAMRDQGEFLSGRKL
TTPPRVFLGAAANPFGPPLDYRPIRLEKKINAGAQFVQTQYCFDLVRLREYMSRVRDMGL
TERCYILTGVGPMPSARTAAWIRDNVPGVHIPDAVIKRLLGAENQKEEGVRICVEMIQAV
REIEGVHGVHIMAYKQEERVRDIVEESGVLEGRIPWYPGVSNDQQGQQN
>A0A2E0GSG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MRVNPFNQKDESFIFTAETTPSVSTNLNESVEKISSLIGVADAVNITDAPNCKTKLSSLV
VAGEIKKNGLDVILQITGRDRNSIALESEILGALSLNIDKILCLSGDRPPEDGPMAVNEM
NSSNLIELLNKMSAGNLLDGTEIKEHKKIYSGCADSIHDHYVRDTHSNFFVEKVRMGVGF
VQTQYCYDLNLCKKYSEFILENNLSDQAKFIXGLGPLKSAKQASWMRENLYGVKIPDSII
LRLEEASSPLDEGXKICEEIIQELIDLKGISGVHLMGPNCEDQCAEXIKYFR
>A0A3C0L433|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTTLPISFEFSAPKTEAAASGLRRAHDRLKRFDHEFVSVTYGAGGSTRDGTKDTVIALSQ
DGASAAPHLSFGGDNSETIGELLKAYQDAGIRRIVALRGDRQSGLGTPKIVHASELVKFI
RETTGDWFHIEVAAYPEIHPESKSVGSEIAFFKEKVDAGANGAITQYFYSDEAYFRFVEE
SAKAQIRIPIVPGIMPITNLTGLQRFSQICGADLPRWLVKRLEDFDDDDALKDFGAEVVT
RLCEQLIQGGAPALHFYTLNQSKPSARILDNLGF
>A0A2D5PQX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MFDDKELIFTAETTPDLSMDLESSVNKIIPLVGLADAVNITDSPNCKTKLSSILVAAEIK
RKGLDVILQLTGRDRNRIAIESEIIGAASIDINKVLCLTGDQPGENGPKAVNEFNGASLI
ELINILNSGKITDGTEIASPQEIFAGAADDLYTHQSRPEAIDSLMSKINSGAKFVQTQYC
FDIEVIKFYSDLILNNGKDDSWKVLVGMGPLKSAKQADWMRKNLWGINISDEIINRLDAA
EDSVREGEKICIELIDQLK
>A0A0V0W5P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella sp. T6|TrEMBL
LMASLEAVVLKATRHDLNSAAKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTTEGL
INLLKRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCILNFCLLDTMLHITSVQY
DEKTVLFNLERAKKIGIRNILALRGDISDDANVTTTDFQYACQLVRFIRSHYGDYFTICV
AEDLLNLKAKVDAGADFIITQLFFNEMHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMK
IVQLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRKLLNREHHVVPGLHFYTLNQ
EKSILEQIGFWKKAPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYLCRTRDWKQFPHS
RWGDVGNPAFGNLKHYLFSCIDQMDDSCALDMWDKELSTLEHVRDIFCNFIARTPNRHGH
SVRRLPWNENHLDPAADVLKNELIYYNSNGILTINCQAAVNGLPSSDPIFGWGEANGYIY
QKVNARYILISLGYLEFFASSTCTTILLNHVQNFPSINYHAINFDGSFETFNYDEDATVA
LTWGVFVGQEIVQPTVANAASFRVWKVVAQLSFIQFSLHTFGIFLFVFEQDEAFDLWQRW
AGLYESRSIGRKLLQRIHDDYRLITLIDNDYPQPCSLSALLRAVISDYWGKKLDDG
>A0A0M1GMN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus sp. C1|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPE
>A0A2D8Z9E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MANEQVVSFLNDFSIEVTPNAAKKIDNFSDYLSPGTLIYIAHIEGTPIEETVATAKKITD
QGFKAMPHFPARIIKDKDTLKDWIGRYKNEAGVENALLIAGGANKPYGEFDSSIQLIESE
LFDKAGFKNIHIAGHPEGSKEIDPDGTTVNVDQALSWKNEFSKRTDASMAITTQFCFDSN
SVIEWANGIQKSGIDIPVHIGIAGPAKLQTLLRYSIECGVGASIKILQKRAKDITKLLLP
YKPTQIISELAAYKSSNPDFNIEKVHFFPLGGIKQVSQFVKEI
>A0A3A4W348|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MLSQKQHERVFSFEFFPPKNEDAAVKLRETRAELARLNPRFFSVTFGAGGSTRDRTFETV
LEIQRAGLSAAPHLSCIASSRAELRELLSAYKRH
>A0A3M0YD85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
PEFFSVTYGAGGSTRERTLETALEIREATGIDVAPHLSCIGSTREELRNILKTYMAHGIR
RIVALRGDLPSGMAEPGELRHANELVAFIREETGDHFHIEVAAYPEFHPQAKSARDDLFY
FKQKVKAGADSAITQYFYNPDAYTAFLEDCRELAIPIIPGIMPITNYTQLARFSAMCGAE
IPRWLRWRLEDLQEDPDALLALGKKVVIGLCQRLIEEGAPGLHFYTMNRAEPTFSICQAL
APALSA
>A0A389M4D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKEIKKMEKIQLSCEFFPPKTAEGFKKLEIVADKLRVLNPHTLSVTFGAGGSTQENTFKT
IKMLQALNIAPIAPHLTCIGSTKETILNLIQTYKQEGFKHIVALRGDLPDGMIDPGIFKH
ASELIEFIIKHTHDDFYLYCAAYPEFHPESPNPKTDLNALINKFKHGAQAAITQYFFNPD
AYLALRDELIHTKCDKPLIAGIMPITNYTQLARFSNMCGAEIPRWLRMRLERFGDDLEGL
KEFGAETMARLCETLIKEDVNHFHFYTLNQAKPTLQIVSKLGLI
>A0A2E8VSH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPLPPISIEFFPPKTPAGTRKLHKVREQLNVFEPEYFSVTYGAGGSTRSGTRQTVLDIRA
AGCAVAPHLSFGTDEPEVIGELIDTYRDAGIDRVVALRGDAPSGVGGSGQLRYAKELVEF
IRERTGDHFHIEVAAYPEIHPESRSIEADIHYFKEKVEAGADRAITQYFYNADAYFRYLD
LCSRAGITVDIVPGIMPITNYVNLKRFSAGCGAEIPRWLDRQLESFGDDTETLFAFGIEV
ITTLCERLIAGGAPGIHFYALNQSDPTRQIIRNLS
>A0A2E7XI90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTYYQAFGERGFVLSAELQLKPDMSASDVVADGRALSANVDGVVLTDNQYGQTHMSTSA
AASLLLGAGIDPIVQLSCRNRNRTALVSELLGVRALGATSVMLIEGAKVPKGFEPRPRPV
LDMHAKELIATAKLINEDGALSGTDFLIVTSGTVHSPQPGWEPEELLAKSEAGARIIMTQ
LCFDVDLLKRXISTLISKKMTHQVRFIVSLATLPSLSIARFLRDNRRRALIPASVLKRLG
QSNDAEEEGVLICSELLQQYSEIPGISGANLMTLGTVDTIGAAISASGVRNEQGLE
>A0A2E7XMW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKISEILKRVCPAFSFEFFPPKDDDGFDKLFQTIDQLKRWNPAFVSMTYGAGGSTRAKTI
DLVGRIKDEIGLESMAHLTCVGH
>A0A2E4KVX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSIPLHPGIMPIANINALQRLGAKAGADILRSLAKSMCSYASDDKGLVDFGVEVVIKLCE
RLLELGALGLHFYTLNRLGASSQLCRNLGFLER
>A0A1X3P6Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nesterenkonia sp. PF2B19|TrEMBL
MTMARPLTRNDDERAVLARLATGISYEVMPFPSTVGTVRAHVPTEVPLTVTATGGKGLEP
TIATSIALRQAGYTVAPHLAARLITGPEELDQILTRLEAGGVDRLFVIAGDAGQPAGVFT
EALDVLRALQDRTHLFKDLGIGGYPEGHAGLSDEQVRQAMRDKAPYAHRILTQICFDADA
FLRWGAQLRTDGVELPVYAGMPGPVSRQKLMRISASLGLGQSANFLKKQRTMLWRFFSPA
GYSPDGLVRGLVRGLPESRAHIAGFHLFTFNEIAATEAWRRRLLAEAGLG
>A0A534ASH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNAESARTPIRVSFEFFPPADEAMGAMLWKSIERLAPLAPRFVSVTYGADGSTRERTHNV
VTRIQRETPLTGAPHLTCIGASREEILEIARGYWDEGIRHMVALRGDPPQGEGARRPNPR
GFRYASELVAALAGLAPFDISVAAYPEVHPEASSAAADLENLKRKIDAGATRAITQFFFD
TDAFLRFRDALAAAGVHAPIVPGILPITRFPQVLRFAKACGTTIPGRLHERFAGLDDDHE
TRRMIAASVAIEQVEALRRHGVSEFHFYTLNRAELTYAICHALGLRPHARSASAALQEAR
A
>A0A673GKL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus rhinocerous|TrEMBL
MKSKELSVDLGDRIVSRHRSGEGYRTISAALKVHRSIFDRMGSGGPLFIDVTWHPAGDPG
SDKETSSMIITSTAVNYCGLESVLHLTCCNQTQEKITAHLNKAKRLGLKNIMALRGDPIG
EDWVEEDGGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGA
HFIVTQLFFRAETFLKFVKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEITQ
VIEPIKDNDAAIRSYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAED
PRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIHRTQDWDDFPNGRWGNSSSPAFGELTD
YYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITAQTNRNGHKVMCLPWNDDPLAP
ETNLLKDELEKVNRRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENV
TALLQVLKKYEPRVNYHIVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMY
WKVMLFPLSNHL
>A0A0J8SQP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. VT 511|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLAPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKSTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMMKHKIAGIVITPHMLRVLAQEKQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVET
KKELVPQLAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASFWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A1H9LR92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio fibrisolvens|TrEMBL
MTFENYLNNKIMLADGAFGTYFASKYGTGALPECANITDPSKVIDIHSDYIKAGANLIRT
NTFACNTLNLGPDMKKLGDHISAGCRLAFMASSLYSDTSDIQDSNTGIPNTGISYTDQSG
SDENSDARINDTNADNQGKRQIFVAGDVGPIPFIPGQDDEKISEEYFFMVQTMYNSGIKI
FLFETFAGIDNILKSLNWLKEKKENEPDLFVWVQLCSNQHGYTNEGIHVRNIIKELSAKK
LVDAAGLNCGIGPASMRNILDEIDFTGIKYVSAFPNASFPQGMLSRPIFSGNEKYFASKM
EEILSLGADIVGGCCGTSPEYTSKIAELDLSTKKSHAFKGEADLSIKVREKDSSFWEGKT
SKKLIAVELAPPFGADDKKLMDSANALTKYNVDAITLPDSPSGRTRADSILAGLKVNSET
GIAAIPHICCRDRNVISLRSGLLGAYMNGIRNILAITGDPVPTLMRQEARSVFNFDSVGL
MKVIAELNREEFYRDPITYGGALSYNRPNTSVELSRMIKKIEAGASFFLTQPVFSDEDIE
KLAFFKDKMKEANPDVKLFCGLMPLVSYKNALFIQNEMSGINVPDEVIARYKPDMSREEG
EMVGVSVVRDVIAKTKDFSDGYYFSIPFNRVYLLDKILD
>A0A1F2PAF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Syntrophoarchaeum caldarius|TrEMBL
MKKIKEGKFVFTGELEPEKTTDLTELVESAKKLLGHCVACNVTDNPQSMAYMSSLVASHI
VQRDSGMECVYQLRCSDRNSIALTSDLLGAGALGIRNVLALTGDHTSLGDYPGSMPVFDL
DSGQLVYLIRRMVDEGVDLNGKPIEHPPRFHVGVAGNPNADPLDSEILKLKRKVEAGAEF
VQTQVIFDIEIAKTFLKEMEKYKVPVLIGIFPLKNYGTADYFDKYIPGVHVPKDLLAKMK
EASEIGDKKKKMERYDEINLDYYGDFVHEIAHNTSAAGIHVMAVAYERITPPLIECAKI
>A0A7W3YEF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter penaei|TrEMBL
MSLSTRTPISFEFYPPKTDEQRTQLDRTAARLKAYAPEYVSVTFGAGGSTLSHTPDAIQR
LAREHGFSAAPHITCMGGSREEIRGMLKLYKALGATRLVTLRGDLPSGMASPGDLRYAND
LVRFIRDETGDHFHIEVAAYPETHPQARDAHADLTHFKRKVDAGANGAITQYFYNADAYF
RFVDDARAAGVDVPIVPGIMPISNFSQTRRFSELCGAEIPRWISQRMQAYGDDVTSIRAF
GTEVVAQLCRRLIEGGAPSLHFYTLNLAKPTVSVLQQLA
>A0A412KUQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mitsuokella sp. AF21-1AC|TrEMBL
MKRISVELVPRDEEALRQELALLHQYQEKVDVINIPDLLRFPLRSWQGAAIAKDFFPASM
PHIRAMDINLEEELSMKEYLRAHDIREVLVIEGDPPQDMMHEVYPTNSVDVIWKFRKEMP
EVKVYAGIDQYRGSMAQELYRVKRKLQAGAAGFFTQPFFDMRYLAVYADMLQGLEVYWGV
SPVMSARSQSYWERKNNVVFPHSFRPTLEWSVDFAHEVMEYAEREQTNVYFMPIKTNLAA
YLAGVFA
>A0A2P8FED7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shimia abyssi|TrEMBL
MTAPHISFEFFPPQNLEASFRLWDTVQALAPLEPRFVSVTYGAGGTTRDLTRDVVATLHK
SSGLNVAAHLTCVNASRAETLGIAREFAKASVSEIVALRGDPPKGSTGFEAHPEGFANSI
ELIEALAETGDFTIRVGAYPEKHPEAADMAANVDWLKRKIDAGATEAITQFFFEGETFLR
FRDACVKAGIDAPIIPGILPIENWKGVRNFAKRCGTEVPAWLEDAFAKAIRDGREDLLAT
AICTEMCSELLDEGVDSLHFYTMNRPELTRDVCHALGVVPQVRLENVA
>A0A1Z8V4F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium TMED61|TrEMBL
MSALKSGSNLEKVLAGGHFAVTGELGPPKHMDTTVVDRKIDLLKGAVDAANVTDNQTGIV
RLSSIATGIYMAQHGLEPVIQMTCRDRNRLAIQSDLMGAYIHGIRNVLCLSGDHQSFGNH
PGAKNVQDIDSMQLIRMLQEMRDKNQFQCGDEIKGGGPKLFIGGAGSPFSEPISFRPLRI
AKKMAAGVDFIQTQMIFDMNIFRQFMSRLVDLGVTEKVHILAGIGPLKSSPMARFLNEKI
PGIIIPEDLLKRMDGAVQGISEDDKEGRRDAWRAEGQNICIEQIEELRQMEGVSGVHIMA
IEWEAAIRPITERAGLLPRPIV
>A0L7S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1)|TrEMBL
MSLRNANCRLSVELVPRDVEVLKDEIKRVHQHFPQITTINIPDLVRYPIRSWDGCVLAKD
HFSSAIPHLRAMDMPEQPILPMLDVLDANGITEVLVISGDEPVAGEVHRGPDSLEIIQRF
KTLAPHIKVYAALDPYRTNIQHELAYAQQKLEAGAAGLFTQPFFDHRLMQIYADQLQGCA
VWWGLSPVVTEASKNYWSRVNRVVFPASFQADLAWNQAFARDVLDMIHEMGHHIYFMPIR
VPVEDYLAGVLAE
>A0A2N9Y4F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snodgrassella alvi|TrEMBL
MSFTKLSFEFFPPRTEEGRRKLAVTRKQLSQYQPEYFSCTYGAGGTTRSGTLQTITDIMN
DGVAAAPHLACIGASREEMISLLQTYKDMGIRHIVALRGDVPSGVGFGHHGLRYANELVT
LIRQEFDDWFHIEIAAYPEFHPQSRSAEDDINHFVRKCQAGADSAITQYFFNADSYFWFV
DEVQSKGIDIPIIPGIMPIASFSKLARFSETCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCDHLLQQGAPSLHFYTLNQAGLVSTICQRLGY
>B8FFS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatibacillum aliphaticivorans|TrEMBL
MRVSKLYQDSQKPVISFEFFPPRDEKAGQAFDKTIDALKPLSPDFMTMTFGAGGSTKDGS
YQAVKNLMGREIPTVAYLAGFGLSPDYITQVLDRYRELGVETIFTIRGDEPREKDFQPHP
DSFPYACDLIKFIASKYDFDLGCAGYPEGHIDAESLDKDIEHLKRKVDNGAKYVVCQYCY
DEDFFFAYVDKCRAAGIQVPIIPGIMPVYTVKLTRMLAKICGTTIVNDMAANLDKLEGAD
AQAVLDYGVEFALEQCRGLLKKGVPGLHIYTMNRAPSTTRILTALRDENLL
>A0A417M4B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. TF11-13AC|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPDLCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A3M7NID4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetothyriales sp. CBS 134916|TrEMBL
MHITTKLNAAHSLGRPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
ALTCEMVSAAQTNYGLETCMHLTCTDMERSKVDEALSRAYKSGCTNILALRGDPPREQEK
WEAKEDGFRYAKDLVKHIRATYGDHFDIGVAGYPEGCDDEPNADVLIDHLKEKIDAGAAF
VVTQMFYDVDIFLNWVKKCRDKGIAVPIIPGIMPISTHQAFLRRANWTKCHVPEKWHAAL
EPVKNDDGAVKEIGRDLVVEMCQRMLEAGILHLHFYTMNLAQATRMILEELNLTPETSGV
PLSKPLPWRPSLGFGRREETVRPIFWRNRIASYIARTTEWDEFPNGRWGDSRSPAFGELD
AYGIGLKGSNESNIKLWGSPRSLREVGDLFINFLEGRLDRLPWSEGSISAEADSIKADLI
KINRRGFLSINSQPAVDGVPSSHPVYGWGPQGGFVYQKAYLELFVLPSVIDEVMKRLDAN
KNLTYFAVTKNGKLRTNSPDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGHD
WSKCYPQGSGSRGLIETIMDECYLVNIVNNDFHQTDEIFRIFDDLEVTDIDRVFENDADQ
VDQNGIPGTVNGAT
>B8FFI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatibacillum aliphaticivorans|TrEMBL
MKLKEALDKKLFVVTSEVQAPFDENPQELLDNLKQIRGRVDGVSIAESDIQGIVGDTVKT
CEILNENRFDAIYQTTTRDKNRIQLQKDLLTAHDAGVENLLVFTEDYRITGDSLQEMMFF
HVDAGKLDSVLKSMREGHSVEGKPLDKRAEFLLGSGVESGWGRNVPELELKEMEQMTGVG
AGYFLSTPVFDLDLFEKFLKQANTFGVPVIAELMILRTAGMARFLNRHIRSGLVPDWVIK
KLAQAPDKQKASIELFADLAKGLKDLCDGVHIISIGGTDKLKHYLDAAKLR
>A0A0J9X2J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geotrichum candidum|TrEMBL
MKITDKLNEAHKSPAGSAPTYSFEYFVPKTSQGVQNLYDRMDRMYGLGPAFVDITWNAGG
RLSNLTCEIVETAQATLGLETCMHLTCTGMPREVVENALKQAHDAGCQNILALRGDPPHE
SEKWTATEGGFSYAKDLVKYIRATYGDYFDIGVAGYPEGHPEEPDVDKLVGYLKEKVDAG
ATFVITQMFYDADNFINWVHKCRAAGITVPIIPGIMPISTYDSFMRRANWCQIQIPESFL
KTLEPIKGDDAHVRDVGTKLVANMCERIIDAGIKHLHFYTMNLEKSVVMVLEELKLVQDE
TPVETVATNALPWRQSLGRARREESVRPIFWKNRKHSYVSRTQDWDEFPNGRWGDSRSPA
YGALETYGVLLRQPSAKAIKLWGHPKSSHDLGELIVHYLRGDVKSLPWSDSPVSNEIDSI
KERLIALNERGILTINSQPAVNGVRSTDPIHGWGPSNGYVYQKAYLELLVPPEVNAWLIS
KINAHNEDGIITYYSVNNDGDLLTNTPDECGPNAVTWGIYPGKEVIQPTIVEKISFLAWK
EEAFRLTLEWSHCFPEGEAARKFLETVSKEWYLINIVFNDFQNEYGIFEIFDEK
>A0A513RL21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. S3|TrEMBL
MSFLEKLNNQILIADGAIGTLLYTYGVDSCSEELNLSQPEQIQNIHQAYIDAGADVIQTN
TYAANYLKLQRYGLEDSVKEINSAAVRNAKKAAQNNAYVLGTIGGNRGIKPNSVSLEELK
RSFREQLYCLLLEGVDGLLLETFYDLEELETVLTIARKETNLPIVAQVSLQEPEILQNRL
PVNEALTRLEGLGADCLGLNCRLGPHHMLVALEQIELPKHAFLSAYPNASLPTYTDGKFH
YEGDADYFRQSARAFRNQGVRLLGGCCGTTPAHIKAFADELKNSVPVTEKVVQLKPKKIA
VESSTAKREFSPLQEIVKERPSVIVELDPPRKLDTTKFFEGAKALKEAGIDSITLADNSL
ATVRISNESLGYLIKERLNVRPLIHLSCRDRNIIGLQSHLMGLHTLGLNDVLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTAFSIAAAFNPNVRSVEKAVK
RLEKKIHYGADYFISQPVFSEEKLLEVYEHTKHLDVPIYIGLMPLTSSKNAEFLHNEVPG
IKIADSIRERMAGLNDNPLQAAREGIDITKSLIDAAMDLFNGIYLITPFLRYELTTELAL
YTKKRARYLRGNSYAENTVY
>Q8ZWI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)|TrEMBL
MEIVAELTPILYREKLLARLDALTRYVEKVDIPEAPGGKPSAHSIAVGALAKQLGIEPIV
HIRLLDINMTAYKSLLGGAYLLDIKYVVVLQGDPPAEGRPVGEISTEEAVAVAKKMGFKA
GALLSLRRDYKQRLKIGADFYLALHLREAEQLADLPPVIYPYILVKTEKNFDLFERLGQT
AVSPREALELVRKLEGLAPGVVLSVPRDFQTLLGLLQEVKIRP
>A0A0E1VD48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus epidermidis W23144|TrEMBL
MSHLLNQLKSNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKSFGLEHKVKEIHQAAVQIAKRAANEDTIILGTVGGFRGVRQEDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELTRIVTATRQKYDIPIIAQLTASNTNYLVDG
TEINEALKYVVECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDIAQELINEGVRLIGGCCGTTPEHIRYIKSAVKHLKPVKDKKVIPINKAS
SQKQARVLKQNLTSKVKNGPTVIVELDTPKHLDTDTFFDNVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQRYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGINTDGDALKKHTNFNIAGAFDPNVRKLDGAIKR
LEKKVASGMSYFITQPVYSKEKIIQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSDDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAA
>G5R8F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Senftenberg str. A4-543|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPSL
>A0A8B3AMH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea formicigenerans|TrEMBL
MTCKIRDILKDQTPQVSFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKN
TVSIASHIKDDFGVTSLAHLTCVSSTREEVHQVIDKLKEKNIDNILALRGDIPKDNAFPL
PNQYCYACELIEDIKQQGDFCIGAACYPEGHVETEHKKDDISNLKTKVDCGVDFLTTQMF
FDNNIFYNFLYRIREKGILVPVLPGIMPITNKKQLRRSMELSGTAVPQRFLAIIDRFGDD
PEAMKQAGIAYATDQIIDLIANGINHIHVYSMNKPDVAAAIMNNLSAILKVED
>A0A843YLG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciimonas soli|TrEMBL
MKQTKQKNFSIEFFPPKTPEGVEKLRVTRAKLAELHPSYFSVTFGAGGSTQKGTLDTVLD
IRREGHDVAPHLSCLGSSRASLREILTQYKDNGIKRLVALRGDLPSGYGAMDFSSGEFRY
ANELVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDVQRFVAKVKAGADGAITQYFYNSD
AYFRFVDEAQRLGATVPVIAGIMPITNCSQLMRFSDMCGAEIPRWVRLKLASYGDDTDSI
RAFGLDVVTQMCERLLAGGAPGLHFYTLNNSAATTAIWQRLK
>A0A7C7ZNG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cycloclasticus sp|TrEMBL
MALESHQPISFEFFPPKTEEGREKLLAVSKKLGQIDPAYFSVTFGAGGSTQQGTINTVLD
IKKQGFSAAPHLSCVGSTKENIREILANYKTQGVDRIVALRGDIPSGTLDVGEFRYANEL
VGFIREETNDHFHIEVAAYPEIHPQAKNAQTDLANFKQKVEAGANGAITQYFFNFEAYIR
FVEDCDKMGINVPIVPGIMPITNYSQLARFSGMCGAEIPRWIAKRLEGFADDRESIKAFG
ADVVSELCQSLLDYGCPGLHFYSMNQAEASLLICRNLGIENA
>A0A137QYT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucoagaricus sp. SymC.cos|TrEMBL
AGGRTSELTSEMVKTCQSFIGIETCMHLTCTNMPKEKVDIALREAKAHGCRNVLALRGDP
PAGKEEWEAIEGGFVHGIDLVKHIRRNYGDYFDIAVAGFPQHMLLPPDELEQEMIWLKEK
IDAGCNFIFTQMFYDVETFIKWYHCVREHGITIPIVPGIAPIQTWNGFMRATSLAKTVIP
QTFLDALEPVKNDDEQVRKIGTKLVAGMCRRILDESLGIRGLHFYTMNLEKATKMLLEEL
NSGNDQAFALASSTTLFFTLNFSVLMVTKQSLTPSRRAETIRPIFWANRTKSYLSRTENW
DEYPNGRFGDSRSPAYGELDGYGVWIKQTLGFLTINSQPAVNGARSDDKIFGWGPANGYI
YQKAYLEFFVSPTLLDLLIPHIERDSNITYYVINKQGDLRTNTHSDGPNAVTWGVFPGKE
IIQPTIVEAISFMAWKDEAYELGKQWASMYDADSLSYKVISDLMENSLLVNVVHNDFHDT
EAIFKPFFKAGAEFISKSKPLVNGH
>A0A3M9ZP60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon S13|TrEMBL
MAARAAARSVLGIVYEANPPRDEGDAGGLLEAMSRRLGRVIGLADAVLVTDGVLGTRRVG
VLDACAAIAASHPRAEVMISLRTRDRTYERLAGDIAEAARVGVSAVLLVRGDPPQYAGAR
DTNLYPGAALSRLRAESRTCGVRMVLSLPAEPDPAGTRKKLAARPDAFVTQVIASEAQAA
GIVEEMAAHGIGVTPCVMVPSEKNAPSARALGLDWSAYEGDCGAFVRRIHSLAGGVLVTS
PRDLAAAEAAIASAR
>A0A1H2ZN09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. CF384|TrEMBL
MDSLLRERIVRKEPGIITYGMTPPKESHTPDKIAEIAQKQIERLAGLHIDGLILYDVQEE
SDRIDQDRPFPFLRTVDPTKYSKEYLGELSVPKIIYRCVGNYSSNQFSEWLQAETDQDRF
SVYVGASSSKQATSMRLPEAYELSKRMDPNLSFGGVVIPERHTMKNDEHLRVVDKMNSGC
QFFISQATYNIEATKNFLSDYYYYCRDQEIDMVPILINLAPCGSPKTLEFMKWLGISIPK
WLENDLKHSRDILDKSVTLSHRMFEEIFDFGLEKGIPLGCSVESVSTRKVEIDASVALLN
EIRATIAKKLVK
>A0A4R9FXT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira semungkisensis|TrEMBL
MKKILDIYKAAKSPVYSFEFFPPKAPEGEVKLFEAVRELSKVEPDFITVTYGAGGSTRDK
TIRLTSELAKEFALPAAAHFTCVGGDKNEIRNILKQIQESGIVNLMALRGDPPKGEGHFK
KVEGGFGYASELISFIKEEGFDFCLGAGCYPEKHPEAKSIEEDVENLKRKVEAGASYLVS
QLFFKNSSFESFLDLIRKKGIQVPVVPGIMPITSFSQIERFKTMAACEFPDELVSELEAV
KDEPEEFYKRSVRFSVAQCRELVKMGVPGIHLYTLNQSPASLDIVRELKK
>A0A1J1EAS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter enzymogenes|TrEMBL
MLPISFEFYPPKTDEQRSQLDKTAAKLRAFAPSYVSCTFGAGGSTLSYTPETIRRLRQKH
ALDAAPHLSCVGGTRSEIRELLALYREIGCRRLVTLRGDLPSGMASAGDLRYANELVEFI
RAETGDHFHIEVAAYPETHPQARDALSDLENFKRKVRAGADGAITQYFYNPDAYFRFVDD
VRAAGIDIPIVPGIMPIANFSQLRRFSELCGAEIPRWIAQRMHAYGDDADSIREFGAEVV
AQLCSRLIEGGAPGLHFYTLNLAKPTLSVLARIA
>A0A2T7BZ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panicum hallii var. hallii|TrEMBL
MKVIEKIQQAAADGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYTNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALAILMNL
GLIEESKVSRPLPWRPPTNVFRVKEDVRPIFWANRPKSYITRTLGWDQYPQGRWGDSRNP
SYGALTDHQFARPRGRGKKLQEEWAVPLKSVEDISERFTNFCEGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLELFCAKEKLD
QLVEKIKAFPSLTYIAVNKDGESFSNVPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWTRGWGCLFPEGDSSRELLEKVQKSYYLVSLVDNDYIHGDLFAAFKEI
>A0A369JWU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypsizygus marmoreus|TrEMBL
MKISHKIEQSAKEEKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPKEKVDIALRDAKKHGCRNVLALRGDPPTGKDE
WEAVEGGFMHGIDLVRHIRREYGDYFDIAVAGFPQHQLLPPEERDLEMKYLKEKIDAGVN
LIFTQMFYDVQVFIDWVRSVRAAGITVPIVPGIAPIQTWNGFQRATSLAKIAIPQHFLDA
LEPYKNDDERVRAIGTKLVADMCRRILSENLGIRGLHFYTMNLERGTKMLLEELNLVPRV
ETIKPLPWRQCLTPNRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKVDALKLWGHPTTFQDVATLFARFCTQDLSALPWSDQAPSTETSIISKQLA
RMNELGFLTINSQPAVNGVRSDDKVFGWGPSNGYVYQKAYLEFFVNPTLLSLLLKHIERD
SNITYYVINNRGDLRTNTHSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELGQQ
WARLYEHDSPSQKLISELMDTCFLVNVVHNDFHDPEAIFEPFFKAGAEYLAMNPASPPTV
NGY
>A0A327YPY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger aestuarii|TrEMBL
MTRPEISFEFFPPRNIEATFRLWDTVQVLSPLAPRFVSVTYGAGGTTRELTRDVVSTLHK
HSGLRVAAHLTCVDATRDETLAIAAQFREAGVTDIVALRGDPPKGATGFTAHPDGFGSSV
ELIEALREAGDFNIRVGAYPDTHPEAGSARADVEWLKRKLDAGATEALTQFFFEPETFFR
FRDACEKAGIDKPIVPGIFPVENWKGARRFAESCGTKIPAWVIEAFDKAEQDGRQDLLAT
SLCTELCSELLDGGVEQLHFYTLNRPELTRDVCHALGVTASSALNKVA
>A0A3A9YBJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora musae|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTPEGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVAHPEGVRYAAELVQLIRGAGDFSVGVAAFPYKHPRSPDVTSDTEHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCATPILAGVMPVTRMATIERSVQLSGAPF
PPALAERFARVADDPEAVRRLGVEQASEMCARLLDEGVPGIHFITLNRSTATREVWQNLR
VQART
>A0A0M4LCR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. ERGS1:01|TrEMBL
MSPPSLIQATASTPASAPIALSYELFPPRNEAAAASLWATIRELESTNPDYVAVTYGANG
SNRDTALELSHRLLTETSLRPLAHLTCVGTTADELAEIISELLDHGVRGILALRGDLPKD
PAAARKPGSLAYAQDLIELIRRVEQRRSALLCAGKVAIGVAAYPAKHPESPSIEHDVEVL
LAKQRSGADFAITQVFFHADQYKDLVTRARRAGVSIPIIPGVMPLTSLRRVERLGVLTGV
EPDPKLLDALGRADDAAESRRIGVAATVDLARAALDAGAPGIHLYTFNEHAAALDVLDKL
QLLRPSRPAVGRRPAAPELVQA
>A0A239ZZ77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella rodentium|TrEMBL
MTLREKHKNGQFTITVELDPPKSSSAQKVFDQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHHEGIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAKAV
FEVDSMGLLDISKTLNSGKDMAGNDLDEPTSFYIGTTGNPGAEDLEIERQKLAAKIEHGA
NFVQTQPIYDLEQAKRYIDAMSEFNIPIMLGLIPLKSFKMATYLHEKVPGISLTQEILNR
VEKGGKEAGTEIAIETLEEIKKIASGVHIMPLNDIDTTLHIIDHV
>A0A098TK62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neosynechococcus sphagnicola sy1|TrEMBL
MTSVFRSAAEAGEFLITAEVAPPKGGDPAHMLAMAEILKGRVHAINLTDGSRAVLRMSPV
AASVILLLHGIEPICQLACRDRNRIGLQADLMGAHALGIRNILALTGDPVKVGDHPDARS
VFDMESVRLLKLIGKLNQGFDWNDRPLTDGVTDLFVGAAVDPQLSSWSGLQRRFEHKLAA
GAQFFQSQLICDFERLEKFMSQIAAGCNKPILAGIFLLKSAKNAQFINRCVPGVQIPQSI
IDRLDRAENPLQEGVAIAAEQVCLARELCQGVHMMAVKREDLIPQILDKAGIHPLNAP
>A0A0M4LYR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. ERGS1:01|TrEMBL
MMLPTRLEIIPTDGIVADVRAQLPAGTTITVTCLPHHGIERTMETATALAGHGYNAVPHL
AARSIVSRKQLAGIVRDCGGAGITELFVIGGDKTHSAGPFTSSEGLMREIAEVSGNTMTM
GVAGYPEGHPSITDGQLLDSLRAKQELASHIVTQMCFSPTAIAGYSAMLLREGVTLPVWA
GVAGAVPRTKLIMLATKIGVGSSLKFITGKAALGKKLLGGGRYQPGELIEDLQALPSPPA
GIHLYSFNNL
>A0A1V5S4Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin300|TrEMBL
MREHIENKMYHIEILPPKQETENLQEELKLFAEKYNKVLNGGYCACITDNAMGYLAFQGT
EIIEHLKLPVFTNQVMIHLNTFHTKADLHNILDSCKSLGIKYLLVVSGDGSERLPKLQPA
DVNAKGITRSVTAVELLKYIESEYPNDFCLGVAFNPYEPAEHEYEKLDRKLKAGAKFIVT
QPIIQKNDVVDKLIDYCSIPVFIEAWMSKKISLLSQAVGYEIPENEQFDPIETLKMLHKI
YSQCGAYLSILGFKTQYALIKDIW
>A0A854M3W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. TMED43|TrEMBL
MALSLQEKIEDTNQGVYLIGTTPPKIGTDKAQLKIIAEKLLARLHEIEYDGVIIYDIQDE
SSRTDKARPFPFKQTVDPREYSHLLRNLSAPDVITYKSVAQRGVEEFKGWLDETKNDYDL
KNVVLVGSPSSVGDIKLSLPDAYKTLAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGITPKRIILTFTPCGGDKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKQIA
>A0A7J9SKZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobellus ruber|TrEMBL
MSLGAQRESGTDAVDGAEYLLNNARFELMPFDSFDEEISHLPEGSSIAITTSPKLGIERT
VERSEEAAAQGYNVVPHIAARYVEGPEQLEEIARRLTEAGVTDIFVPGGDKEEPVGEFES
AYDLLVALEDLEYEFDEVGITGYPEGHEFISEETLAEEMEKKAPYATYIVTQLCYDPDTI
LEWVEDLRARGVELPIEIGIPGVMKYEKLLNISRKVGVGDSVKFLRKTTGLVGFVKQFIG
SRGRYKPDDLIDGLGPYVGDDEYNIRGVHIYTFNQTPDLEEWRRGRLEG
>A0A2T4LS13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus cohnii|TrEMBL
MSQLINKLKQNILVADGAMGTILYSDGLDTCPEAYNLTHPDKIERIHRSYIESGADIIQT
NTYGANFEKLKVFGLEHKVKEIHKAAVQIAKKAANDETFILGTVGGFRGVKQEDLGLEAI
QYHTEIQVDTLVEEGVDGLLFETYYDLEELTNIIKATKRKHHIPIIAQLTALNTNYLRDG
TEINTALQRVVDSGADIVGLNCHHGPHHMQQSFSHIELPDNAYLSCYPNASLLDIENSRF
KYSDNAEYFGKVAEQLIKEGVRIIGGCCGTTPEHIQYIKSSVANLKPVSSKNVIPIKKYN
SPSYANTQQQNLTTKVKAQPTIIVELDTPKHLDTETFFRNIKKLDDAQIDAVTLADNSLA
TVRISNVAAASIIKQQYNIEPLVHITCRDRNLIGLQSHLLGLSLLNVNEILAITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNEGINTDGDALKTKTNFNIAGAFDPNVRKLEGSVKR
AEKKIESGTHYFITQPVYSTEKIEEIYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEDILEQFEAVKDDKEKTKALSLKLSKELIDTVHKYFNGLYLITPFQKVDYTLALASY
SQSITSSKQEAIL
>R5QCV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ruminococcus] torques CAG:61|TrEMBL
MKIIDRLKEDKIHISFEVFPPKTDAGFEKVIAATDAMAKLNPAFISVTYGAGGGTSKNTA
KIASHIKDDLGVASLAHLTCASSTIEEVRDVIENLKENGIENILALRGDIPEGMPFPNGN
RFRYAYELIEEIRKHGDFCIGAACYPEGHVENEHKAEDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGINVPVLPGIMPMTSEKQMKRSQELSGTVFPRRFLALLDRFGSSAA
AMEQAGIAYATDQIIDLLSNGVNNIHIYTMNKPHVAAAIMNNLSEIIKA
>A0A095C5G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. LC363|TrEMBL
MTSNLNSLAEARRAAASPLFANLDGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLAPSFV
SVTYGAGGSTRERTHSTVARIAAESRVPPAAHLTCVEASRAEIDEVAQAYWEAGVRHIVA
LRGDVPGGEPYRAHPQGYANAIELVAGLKAVAPFEISVAAYPEVHPDADCPQSDLDNLKR
KLDAGATRAITQFFFSPDSFLRFRDAAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMVSLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVSTAKDQAA
>A0A7C3IIN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema caldarium|TrEMBL
MNISLEIVPRDEPTIAENIAIASRFPEITLINIPDLLRFPTRSWEACPFIPATYQSIPHL
RAIDFNMDEPFPLTDYFRNHHIDTVLVVAGDPPQDMKHRVFPTHTTDFIKKLKRELPALT
IYAAFDPYRSNIRYELDYLKAKEDSGADGFMSQPFFDVRLLEIYAEYLEGRTVFWGVSPV
LSEKSRNYWEARNRAIFPRSFRPDLHWNISFGRQVLQFCKTHRFDLYLMPIRVDLDTYLQ
GLFS
>A0A7X7HYR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp|TrEMBL
MRIHWTAEQVRDLLDNDVKGIHFYTLNKSDSILSVCKAIGVSSSSQFNKSV
>A0A3N2MZR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Isolate-105|TrEMBL
MTIPELIQRKGSKGFSIEVLPPLKGKGIDQLFAGIDSLKCFEPRYINITTHRSEMVYKST
ADGLYQRVSERSRPGTVAVAAALQQRYGIPAVPHIICSGYTKAETEYALIDLRFLGITNL
LVLRGDKARHDNRFIPNTGGHAHAVELQRQINDFNNGTFVDGTTMDSANDSPFSYGVAGY
PEKHDEAPNRDIDIAWLKNKIDNGAQYIVTQMFFDNDSYFSFVERCRQSGITVPIIPGIK
PIVTKGQLTVLPKVFHVDIPTDLARAVMDCKDDVQAKEVGVEWMAMQMRGLYEAGVPSVH
IYSLNATRSVEKALRLVL
>A0A1V2AT81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MRSETARHNGEIRGDIRLSFEFFPPKNPEMENQLWETVAELKKWDPDFVSVTYGAGGSTK
APTLDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIGT
DYRPHPQGYENAAALVKGLRDISDFEVSVSAYPEKHPESASDAVDIDMLKRKADNGATRA
LTQFFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPSFLDERFA
GYDDDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A5J6Q6M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. RSCCF101|TrEMBL
MRLLQALEAGTPVITAEVMPPRGSDAALTLEHAERLRGRVHAINVTDGSRAVMRMSSLAV
ARLLLDRGHEPVLQLACRDRNRIALQADLLGAHALGIRNVLCLTGDPVRAGDQPGARPVH
DLDSVRLLQQVSAFNRGADPIQGELPDGGTHLLAGAAADPHSPSWSGLRSRLRRKQQAGA
RFIQTQMVMDAAVLRRFQEEIASPLGLPVLAGVFLLKSARNAAFINRVVPGACIPQAIID
RLSAAADPADEGIAIASEQVRSFLRIVRGVHVMAVKAEQRIPAILDRAGVEPISSSGQLG
GGEGSAACLAA
>A0A518AZN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium Pan216|TrEMBL
MKIAELFSHGRCRISFEVYPPKKQEGLEHLYQVVGELCSFDPGFISCTYGAGGSTRDRTL
EIITEIRQRYGVPTTAHFTCVGSTVEEIRAWLTRATELGVENIMALRGDPPKGEAEFKAV
EGGLRYANELVALIRSEFPNFGIGVAGYPETHQEAPSPDVDLDNLVRKVDAGADAVFTQL
YYDNDDFFRFRDRCHERGISVPIVPGILPILSKKQIERITSMCKARLPEELLEKLAACAD
DAEAQEQVGVDHARHQCEGLLREGVPGIHLYILNRSASAQRILNGLADLFPVMA
>A0A087AS20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pullorum subsp. gallinarum|TrEMBL
MSKPLFSLEVFPPKRTAPIGTIYDTLDGLHGVDPAFISVTYGTGKQSDRTITARIANTIR
TEYGIPAVAHLTAQYLDRDQTDEALDMFAQAKVAAVLALRGDRNPEREPAGVFMHASDLT
RYIRQTHPEITVYGACYPECHPQSRDLDEDISWLKVKVDAGASHLISQLFYDNADYLRFL
DKARAAGIDVPIEAGIMPVTNAASVRRMTGMCSSKVPERLATILDRWGDDPNTLKEAGII
YASEQIADLVARGVDGIHLYTMNHPGVTRRIWQNVQGLF
>A0A2U1FPT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora cinnamomea|TrEMBL
MADTLFAPPLTACPKRMVFGPCGGARSDGTCELDAALPCPWCDPEDPVGLRVWPGPTPTP
VPVRAPAVLTDLSVPPYDLAALREALALLAPVSDALLVGEHHHRPDFPPTMMTAEILAAD
AQPWITLTCRDRNRVVLEQEVAGLAALGAGGALCVTGDGRGHDVRPEATQVFDLDSTRLT
HLAASAGLPAAVAVAPAAPPAALRPAALAEKQRAGACLAVANHVGSPHALASFLDAARAA
GADLPVVAGVAVYTDERSAAVLAAFPGLALDAEAVAAVLAAPDPREAGIAAAVAEAEALL
AVPGVVGVNLSGLASADGWRAGAEVKAEVAARLNERQ
>A0A1T4PQV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema berlinense|TrEMBL
MKISEILNSKKVTISFEIFPPKKQEAFDSVKKTALSLSSLKPDFISITYGAGGSTQTNTS
DLAQAVENSGTASLAHLTCVRSTKEQLLQTIQTLKQKNINNVLALRGDLPKDTFEGENLF
PSGFFHASDLVPLLKQNGFCVGGACYPEGHPESSNRDTDIENLKHKVEAGVDFLTTQMIF
DNDMLYSFLYRLQSAGIHVPVLAGIMPITNANQVSKMVDLSNAYIPRKLLSFCDRFRHDS
EAMKQAGIAYATDQIIDLISNGIRGIHIYTMNKPEIAESIVKNVDSIIKAVNK
>A0A0U1Q0T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lampropedia cohaerens|TrEMBL
MTSNPSQPFPRVPVSLEFFPPKTETGIEKLRGVRQQLYALKPQFCSVTYGAGGSTQAGTF
AAVGEILAEGQQAASHLSCVGATREKLRQELAQLQAMGVRRVVALRGDLPSGYGMGGEFH
YASDLVAFIRSETGTHFHIEVAAYPEMHPQAASPQKDLQAFATKVKAGADSAITQYFFNA
DAYLRFMDEIRAMGLDIPVVPGIMPIMGATQLLRFSDACGTEVPRWIRTRLQAFGDDTAS
IRAFGLDVVTQLCERLMREGAPALHFYTMNQSTLVLELARRLRLLEDALP
>A0A4P8JLA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes faecalis|TrEMBL
MSNKQTLSLEFFPPRDIAAQEKLVRTAKSLMGLNPAYVSMTFGAGGSTRAGTVDAVALLQ
KLGFDVAPHLSCIGTAPAQLGEMLDNYRDQGIRRIVALRGDLPSGMGGDAGELRYASDLV
SFIRENYGEHFHIEVAAYPEMHPQATGFSDDLGHFVNKVKAGADGAITQYFFNPDSYFSF
VERAQAQGVTIPITPGIMPITNSSQLLRFSTMCGAEVPRWIRLRLADFGDDRASIRAFGI
DVVARLCQDLLDGGAPGIHMYTLNGADASMAILPNLTWR
>A0A7G6X7B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella qitaiheensis|TrEMBL
MANGLPSKLPGSTPTIRELLATGERSFSFEFFPPKTPEAEEVLWQSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSKDELRSVIGAYAGSGVRNVLALR
GDPQGGPNQPWVAHPEGMNHAIELVSLVRELGDFCVGVAAFPDKHPEASSFDADARVLAA
KAAAGADYAITQMFFGADDYFRLVDRAAALGCDIPILPGIMPVTNIKQIHRMAELTGMAL
PTAVTDRLHAVEDDPKAVRAVGIEIASELCDQLLAGGAPGIHFITLNRSTATRQVYKNLQ
STPV
>A0A2V4I8G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas soli|TrEMBL
MSLLKKTLDANAFACILEFVPKPSAERFATLDTLMARTQLCGWPLTVAIGDRVGSALDMS
PLDAFNSLAEPLPALLHFSGKDRERRELLAQLQRMDAAGLDQLLLLTGDRLPGHVPGERP
VRYLESVAALQIVRQARPHWLLAAALNPFKYQEAEGGAQYSKAEKKLAAGADLFILQLGF
DIDKHQEAFDWMQRQPRPKPLMACIMALTEGRAGMLDHVAGVTVTPSMRALLAAEAAVSK
TYAKERANQRLALQVIGLKLMGYAGVHLSGIHEVAQFEALEQAISALQPQFTSLEDWTPA
WEAAWQEADLEPVTFHPPGHAWRLGQRQITASNKEKVRYHLLSSMHHQLFSRTTALSKAF
GWAVTRPLWANPTAAQWLHQLERRIKRPMVGCDTCGSCRLEDTLYICPETCPKGLANGPC
GGTRLDRCEFGDRECVHSAKYRLAVSVGRTEVLRERLIPCVQVENRQRSSWPVWFEAATS
KSPSRQPDVAAEFNE
>A0A6J4VKK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Thermomicrobiales bacterium|TrEMBL
MLAEGRPTYSFEFFPPKNPAGVEALYAAIADLRELAPSFISVTYGAGGSTRDLTIDLVTR
IKRETGIEAMAHLTCVGHGRDEIRAILERLAEGGVENIMALRGDPPKGTTAFERHADGFG
YGSELIAFIKTDPGFDFCVGGGCYPEVHTECGSADADLANLALKARAGAEFLVTQLFFDN
DAYFHFVECARAAGITVPIVPGIMPVTNNLERLERFGARIPDPLRALIADCADEAAVAAA
GIAWSTAQCRELLERGAPGLHFYTLNKSRSTAHIVRNLGDLLPIPVGVA
>A0A818UFA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sordida|TrEMBL
MTLTHTEKNTASNHCHIHENGIGAPKICHSLDNFSEIKRSESEHSCLAVKGCSFHPVKYI
SLKEKLQKRISNNDRWYSLEFFPPRTTNGAVNLIGCLERMAVGEPLFCDITWHTAGDPAG
TKETSTMMIANTMLNYCNIDTMLHITCYGAKKATMIEYLSKAKDFGIRNLLALRGDPPVG
EKWNPEKTDFRYASDLVKFVREHFGDYFVICVAGYPKGHPDSKSYEEDLGYLKEKVDCGA
DFIITQLFFQAETFLKFVSDCRAVGITCPIIPGIFPIQAYASFKNIVCLTKLDVPDEITA
YMESIKDNDEAIRNFGVQTCVDLCKALLNSDKVHGLHFYTLNREYATTEILKQLGFGFDD
PPLRALPWKKTSKNYVRSKEDVRPIFWSTRPKSYIHRTSNWNEFPNGRWGISSAPSFGVL
TDYHLFYMKIDATRDELLDEWGHELTCEQDVWKMFACYIRGEKNGSDKIVRHFPWKDEEI
SLETHLIHNELIEYNRKGILTINSQPAVNGKPSTDSIFGWGERNGYIYQKAYLEFFTSAN
NIPALRAVLKNFPGVNYHFVNKSGDVNETNTDHEQPIALTWGVFAGREIIQPTVVDTVSF
MIWKDEAFGLWMERWGKLYEPGSSSYSIIEQISNTYFLVNLVDNDYPQGSCLWAVLDAMF
EYQQKTNQDINHS
>A0A7C5CST4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenobaculum sp|TrEMBL
MKIIDLLYKKNGVSFEFFPPKSQKDKELLLQTAQELKTFNPSFVSVTHGASGYTNAEKPP
IEYTKETVLELKNTLGLNIMAHLTCISHTKEELLGILGFYKENGVENLLALRGDIPKNHD
KRGCSHASELIDTIKAYLDDWFCIGVAAYPEGHPESPNMEWEIKYFKQKIEKGASFAITQ
MFFDNKYYYEFLDLCHKEHINIPIIPGIMPITNIKQISKFASMCGATIPSYITDALEDLS
DEDVVKKGVEIATNQCNDLIKNGVKHIHFYTLNKSKAVLEILKQID
>A0A6F8PL72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiosulfativibrio zosterae|TrEMBL
MKSQQQYPQKISLEFFPPRTPEGMEKLKTVIQDFGQFSPDYMSVTYGAGGTTQEKTLDTV
RYIQSETAYNAAPHLTCIGATHESVLALLDTYQAIGVKRIVALRGDLPSGMMDPGEFKYA
SDLVAFIRQERGDAFHLEVAAYPETHPQARNCEVGIKWFKHKVEQGADSAITQYFFNLDS
YLQFVDNCEKHGIDLPIVPGIMPITNYENLIRFSQGCGAEVPRWLKCRLESFEDDKESLL
AFGQEVVQTLAQKLLDAGSPGLHFYSMNQTQPTLDIVKSLTFKN
>A0A6J4UHL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Thermomicrobiales bacterium|TrEMBL
MAQPLTARLAERVTLADGAMGTMLYAAGIGLDECFDALNLSRPEIVAGVHRAYLAAGAEV
LETNTFGANRFKLEHFGLSAKVRDINRRGAKLAREEREVAGLPALIGGSIGPTGRTLPPF
GTTSVDEVRAAYREQIEALLEGGVDFLSIETIGALEEMVAAVQAARDVSDLPIVALMTFA
EDGRTLNGTEPVMVVDALVELGVEVFGANCSVGPRGILRVAREMRRRLDECGHRDVALAC
MPNAGWPTHVGGRVIYPSSPEYFGGFATQALEVGVRLIGGCCGTTPEHIRAMRRALDAMP
TSRGAAAPATGLAPVPAATPIPTKPAIELVATDGPTEIATKLGRDFVVSVEIDPPKGFNP
AKALEGARLLKAAGVDAINVADSPMARVRMSALTLCYLIQHQVGIETILHFTTRDRSLMG
LQSELLGAHAVGVRNILALTGDPPSLGDYPDSSAVYDVDSIGLVRVLGRLNAGQDSAGAS
IGRLANFTIACAVDPTREDLAEEARRLRAKLAAGADFVMTQPIYDVSVWHRFLEIYAGEI
PVPVLVGILPLQSSKHAEFLHNEVPGITLTDDARDRMRRAGANGRREGVKMAQQLLTDLR
PHAQGVYIMPSFGRYEVAAEVMEALG
>A0A2S7FC27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium butyricum|TrEMBL
MIKEFLNNNILICDGAMGTYYSEKTGNDISYCEFGNLNDKNTIRRIHEEYIEAGAKLIRT
NTFSANSKELGVSRKTLKDIIESGIEIAKEAVYNKEVFIGASIGPIRENGADENFVEVLE
EYKFIVDCFLDNNINVFIFETLSNLDYLEEVSTYIKHKKPESFILTQFAVKPDGFTRDGY
SVSKIVGEVKKINTIDSYGFNCGSGPTHALELIKKIDIGDDIVSSLPNAGFPEIIHERTV
YPNNPVYFARKVKEIKKLGVSIIGGCCGTNPSYISKLRETIDNKPEAGDKIKRYEHETYN
EKNIIKNTFKEKVENGDFVIAVELSAPVDTDINKIMTGAKVCKDNNIDIVTVPDSPMSKV
RADSVVMSSKIKREIGIEAMPHMCCRDKNTNAIRSSLIGGHIEEIRNILAITGDPISDAS
RIETKSVFNLNSFKLIELINDMNNEVFTSDDIFIGGALNLNVLNKEVEYGRMMKKVERGA
KFFLTQPIYNDSAVEFLKSIKERTDVKILGGILPVVSYRNAMFLNNELPGVTIPQEILNR
FSEDMSREEGQNIGIDIAVSMGKKLKGICDGLYFITPFGRVNMIVDIVNRIKEV
>A0A2S9KU62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia ambifaria|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVPVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRADLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFTQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNAASATQTICERLAL
>A0A4R1VSP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. ST904|TrEMBL
MTTPIIHPNWARPALNMVDGYSLEMTAKDVEALRGAAAAIAPETPIAVTFLPGEEFESRI
AAARLVRELGFEPMPHFSARRIASAEEFERYLAAVTREAGVKRCFVIAGDPSEPEGPFTD
SSALIATGAFERNGITAIGIGGHPEGHPNMTEEECWQVLSGKCAEIESRGMAPLIVTQFA
FDAAPVLDWLTRLRARGIDAPVRLGVPGPAGIKTLMRFAARCGVGASASVLTKYGISITR
LIGSAGPDKLVDALERGLAPAHGKVRLHFYPFGGMEKTVDWINEYARRH
>A0A3M7KFZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium PRS1|TrEMBL
DIHFLKKKIKNGATYIVTQMFFDNQKYFDFVDKCRKAGITVPIIPGLKPIATKKQLNLIP
HRFHVDLPEALIKAVVKCKDNTQVRQVGVEWCVQQSKELEKAGIPVLHYYSMGKSDNIKA
IASQIF
>A0A448YMP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brettanomyces naardenensis|TrEMBL
MKVTEKLTQAHEDGKAPATFSFEFFTPKTSQGVQNLYDRMDRMYDLNPLFIDITWNAGGR
LGTLTTEMVNVTTTVLGLETCMHLTCTNMKLETIDKALDSAFQCGCQNILALRGDPPLDG
SESTGVFRYAKDLIRHIKSRYGNHFCIGVAGYPEGHPEESDLDKTIEYLKQKQDAGGDFI
VTQMFYDVDLFISWCKKCRAAGITIPIIPGIMPISTYAAFFRRAQWCKIHLPDHFFERLE
PIKEDDSKVRDEGVKLVAEMCAKLLQSGCVNHLHFYTMNLEKSTIMVLRELNLVSKQQLV
GMDTRPWRRSLNPTRSEESVRPIFWSNRKFSYIQRTSNWDEFPNGRWGDSRSPAFGSLEL
CDHELIRHTPKKALSLWGLPTNIQTLADLTVRYLNGDLNCLPWSDSKVTHEIDLIKDDLI
DLNRRGVLTVNSQASINCCPSSDKVHGWGPNDGYVYQKQYLEFLIPSNRLDDLVDEIGTI
NKESGYNILTFYSIGQEGEFTSNARSSSTINAVTWGCFPGKEVVQSTIVEKISFMAWKDE
FFSILKKWISLFRKDTDPGREDAISFIESLVNDATLVNIVDNDYVGEPNTRIFNVLRKLF
PIAE
>A0A5B0MZ81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia graminis f. sp. tritici|TrEMBL
MKISQKLAAAESENRISWSFEYFPPKTDNGLTNLYDRICRMSQLGPIFIDITWGAGGSTS
NLTTEFVKTAHEQFGLETCMHLTCTNMPKSKIDTALKEAYEFGCENILALRGDPPKGSTE
WTATEGGFEHAIDLVRHIRAEYGDHFDIAVAGFPEGHMHSTLSREQQTIYLKEKIEAGAN
FIFTQMFYDVDIFIDWVREIRAAGITVPVIPGLMPIQSWAQFKRVTNFSKTIVPQYFLDK
LEPIQSDDQAVREAGTKLVADMCRKILNSDLGIRILHFYTMNLERGTKMILDELNLNPSR
DITNPLPWKMSLLGKRRSESIRPIFWANRAKSYLSRTETWDEFPNGRWGDSRSPAYGELD
GYGININAATMETLKGLKKFPTSLVDLARIFANYCGARFPGEEPVKYLPWSDIPLSEETN
KIEDVLVKINKRGFLTINSQPAVDGAKSSDPVHGWGPRGGYVYQKAYLEFFCCPEKFQSL
TERLEKDPDVTYYAVTKTGDLVTNNTRPGPNAVTWGVFPGKEIVQPTIVELVSFIAWKDE
AFELGHQWAELYKEIAPESARFIHQIMDSWYLVNIVNNDFRKSNDDSEHSALFQFFGPEP
VIVDQDDLPPTTNGLSHPNGLPKTNGSSTPAISEVNGELKNLAI
>H0FZZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium meliloti CCNWSX0020|TrEMBL
METQLFQTVTALSVFAPAFVTVTYGAGGSTKARSLTTVKRMIGEMEIANTAAHLTCVGAP
KAEVDAVIDEFLACGVRHFVALRGDPQGGIGSVYEPFPGGYENAAALVKALRARGDFEIS
VSAYPEKHPESPDVAADIDMLKRKVDNGATRALTQFFFDNDDFERYLERVRRAGIAIPIV
PGILPINNLTQVQKFAGLCGARVPESIVSRLGPIDDQPEERFREAAHIAAEQVADLVRRG
VSDFHLYTMNRPQLITAVRELMGYDPEIAPAQPADTERSVRAVARA
>A0A0E2AIW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis CL07T12C05|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A4R2HJ94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2572|TrEMBL
MAVDGFELVCEVEPPTRPDLKKVRHQIGVMSPIADAFLIPDNHIGRATVSSVAVANEVQA
MGSRGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDDPAEGARTSQLTVRTMIEQA
RGTSYPGCNPFQVGAATRLRPVPRWKAEADFLYVQVSYDLDELLRWRDSVVLDIPVYAGV
MVLASAKMAHNLAALPQLSIPDALIEAVDRDRDAGVDHACELILKIRDSGAFNGVHLIPV
SRYRQVAARLEREL
>A0A409VAB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panaeolus cyanescens|TrEMBL
HCPGKSSHFLNLEPNVLNSSLQGLQNLLDRIERMRALGPEFIDITWNAGGRTSDLTSEMV
KTCQGLIGIETCMHLTCTNMPKEKVDIALKDAKQHGCRNVLALRGDPPMGKDEWEAVEGG
FVHGIDLVKHIRKDYGDYFDIAVAGFPQHMMLPPDELKKEVQWLKEKIDAGVNFIFTQMF
YDVELFINWVKEVRAAGITIPIVPGIAPIQTWNGFQRATSLAQITIPQFFLDALEPVKND
DEKVREIGTRLVADMCRRILKEDIGIRGLHFYTMNLEKGTKMLLEELNLVPRIETIKPLP
WRQSLTPTRRQESIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELDGYGVWIK
QTKENALKLWGHPETMTDITDLFAKFCSSELSALPWSDQAPSKETSVIAPQLAQMNRYGF
LTINSQPAVNGARSDDKVFGWGPSNGYVYQKAYLEFFVNPQLLELLLKYIERDNDITYYV
INKRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAYELGTQWAKLYES
GSTSQKLISDLMETSFLVNIVHNNFHDPEAIFQPFMKAGAEYEALQAKTNGVNGH
>A0A3B7RD53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces fradiae|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGDWVAHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSTDWESDTRHFID
KCRAGADYAITQMFFDPEEYLRLRDRVEAAGCDTPVIPEMMPVTNVRQLDRLPQLSNAVF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHRRA
>A0A7V6Y5I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterales bacterium|TrEMBL
MSMLKTALENGEFAVTAELAPPKGTDFSRALQIAETFGDRVHAINVTDFQSSTLKASSLA
MCKALIDLGLEPVLQITGRDRNRIAIQGEMLSAGFFGVKNLLALTGDHPTVGDNPGAKPV
YDLDSVGILQAAKVLASGVDMSGNKLEGSPSFFLGASVTPEYDPIELQLIKMEKKIKAGA
RFFQTQAVYDIKTMEKFKEMTKHLNTKILVGIIPLKSAGMAKFMNKNIPGINVPDHLIDR
LKNSNDPVKEGIKIAGELIVELREKNLCDGVHIMAIGAEENIPLILDEAGL
>A0A0M3I527|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ascaris lumbricoides|TrEMBL
MNGEQSASSLEGENLSGRNREQNGKLSMHGGNYIPLHERIRKRINDNSPFFSLEFFPPKT
ANGVANFFNRLDRFPNIKKETSSLSIAAGCLNYCRMDTMLHITCAQYTKEQTLRHLQMSK
AIGLRNILALRGDIPQQDENPIVYKYRALDMIRWIKEEYGDYFTIGCAGYPTGHPEAPSY
AADLRYLKSKVDAGAQLIITQLFFDADVFEKFVHDCREIGITVPIIPGVMPIQGYESIRR
IAALSQLTIPESILKALEPIRHDDDAVRSFGIRHAVEMCRRLLNSGTATSIHLYTMNREA
SCREILQELGLWTRMPMRSLPWKSFEGNHPLRSKEDVRPIFWSTRPKSYVFRTRDWDEFP
NGRWGNSSSPAFNDLADYYLFYLKGQLNKEEQLRMYGYQLENMEAVRKVFVNFITQQPNE
HNVKVTRLPWNEQDIGTDAETVLIRDQLIWCNENGILTVNSQPSVNGAPSTDPLVGWGKP
GGYCYQKGYLEFFTCRKNADVLRNILPSYPRLSCHIINHNASIDWTNTDATTPIAVTWGV
FPGCEIAQPTVVDPLSFHVWKDEAYEAWNNWASIYPDGSKSRKILEEIHDEFCLVTLVDN
DFPKPLIIFEVLAEVLRIAGSTA
>A0A7C8MUM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massariosphaeria phaeospora|TrEMBL
MHISQKLAQAKAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPLFIDITWGAGGRLA
HLTSEMVKVAQSVYGLETCMHLTCTDMEKSKLDDALKEAYQSGCTNILALRGDPPREKEK
WVATTGGFRYAKDLVKYIRDRYGNHFDIGVAGYSEGSEDNPDVDQLIDHLKEKVDAGATF
IVTQMFYDTDIFLDWVKRVRAKGIDIPIIPGIMPIHTHAAFLRRAHWTKCQIPPHWTKAL
EPVKNDDHEVREVGKGLVAEMCRKLIDAGIIHLHFYTMNLAQATRMVLEELEVLPDTESP
LEKPLPWRPSLALNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDARSPAFGELDS
YGIGLKGTNEQNIKLWGKPQCLKDISDLFVRYMSGDLESLPWSEAAISKEAETLQQNLID
LNRRGFLTINSQPAVAGAKSTDPVYGWGPRNGYVYQKAYLELLVSPEYVAEIITRIERNP
DLTYYSVNKEGDLKTNSPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQDW
ANCHSSVSPARYVIEDVMDTWYLINIVDNDFHVAHGIFPLFDGLRVQDMEQPLHPTSASN
GHSTNGTKEEPSKLANVVDAVKSATSTFTNGLNGLNLTS
>A0A7C2S889|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobaculum aquaticum|TrEMBL
MSWQANRVWRRFEDHVVVADGAMGSELLSRLAPGAHLDLAPLEHPREVLEIHLAYLKAGA
ELLETATFAASRPRLERLHAGDLTEAVNAAGVKLAREAREIAGIDCLVAGSMGPLAGVID
LDAPEGPAAIAAAHQEQAAILAGRGADLLILETFFRLDELELAVSAVREVTHLPVVAMLT
FPGEAHGEDWDGAAEQVYRLSQLDVLAVGVNCAPGPGGTLEILERLGTVSKMLAAMPNAG
LLLRRDGRLLLPPATPSYLAAFARRAVALGAGLVGGCCGTGPDHIRAMVEAVRGARPSPR
QTTVVAVPEPVPSAAPEPKPSRSSFAAKLAAGQFVRIVQLDPPKGTNAQRVLEAARGFAA
HPAIDAVDINSNPLARLRMDSLWLAAEIQRTTGLETIPHITPRDASLMGLQAQLLGAWRA
GIRNLFAITGDPSQLGDYPGVHDVYHVDIFELVRAVARMAEGVDCAGNPIGEPPAFCIGV
AVNPNAEDLAREADRLRRKVEAGAQFAMTQVLFDWAPFEKLLDQFQGKLPVPVLVGIWPL
PSLKLALRLHHEVPGIMVPEELLFQLEAAGSGAAEVGAKRARAMLEAAPFYAAGVYLVAP
FRQPGDIVSLLDVAG
>A0A5C4M023|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis alkalitolerans|TrEMBL
MTSVVERVQGDAPVFSVEFFPPRDAADEAVLWRSIRELEAFDPAYMSITYGAGGSSRDGT
IRNIARAATETTLVPMGHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGEWI
PHPQGLSYAEELVELVRSLGDFCVGVSAFPYGHPRSPDLETDTKHLVRKFKAGAQFGIAQ
LFFQAEDFLRLRDRVAAAGSDALLIPGVMPLTTPRTLKTTIKLSGAPCPQWLLDRLEPLE
NDPKAFRAEGLDVVTELCERLIAEGVPDLHFYTFNRSKATSEVVSRLGLIPART
>J3DBU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM79|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARHLATFNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EHVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A3C0FTG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira sp|TrEMBL
MEETMWRSIHRLAPLNPSFVSVTYGAGGTTRDRTHGSVTRIQGETGIPAAAHLTCVGHTK
EEIDQIARSYWNEGIRSIVALRGDLPDAGDKYEPTPGGYAYAVDLVAGLKEIA
>A0A1L6PPX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Tue 6075|TrEMBL
MRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKA
TQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGPWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A4S0R9H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.177.01.1.1|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAARLKDYDPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIEFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLVEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A329VVB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus sp. S10-54|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSINRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGD
LPENSEKPKMYGVDLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFRQLKRFAVMTNVRIPSWMTRMFD
GLDDDPESANLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A1I1DRD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia yuzhufengensis|TrEMBL
METHNFSIEFFPPKTDEGADKLRVVRQKLALLAPKYFSVTFGAGGTTQQGTLQTVLEIQS
EGHAAAPHLSCVGGTAESLRAILQQFQDSGIRRLVALRGDLPSGYGGGGEFRYANELVEF
IRKETGDWFHIEVAAYPEMHPQARSPQDDLQAFARKVQAGANAAITQYFYNADAYFEFVD
NARKLGVDVPVVAGIMPITNYTQLMRFSDMCGAEIPRWVRMKLASYGDDTASIKAFGLDV
VTSLCERLLAGGAPGLHFYSMNQAAATTAIWQRLVK
>A0A3D5CFP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
TEAASLIPAGTKVNVTFLGNEDLPMRVAAAKAVKELGFVPVPHISARRIASQAQLEEFLS
ALAEIGATEHVFAVGGDPATPEGPYPDALTMIRSGVLQQYGVKEVSIAGYPEGHPDIATD
VLWQHLEDKSAALKDAGLDAVILTQFSFDTDPVMAWIKGVRDRGIDTQIRL
>A0A1Q8VRW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MRDNEPTEPTEPTAAAGSRGDALSSTETGSARRLPTVSLELFPPRPGKAASATWGRIDRL
LATGPDFVSVTYRPTFVTDPAGGDSGDEYEGNRCDIAPRVRAVQEQTNPSECVLAHVLES
STIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRADDVAGELRHADDL
VRVIREVETDFFGDSRRHVTIAVAAYPATSDHIEAIEVLAAKQAAGADMAITQVFYDAAD
YVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSTLGSASGATLVER
GIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDAVDRG
YLQATP
>A0A2W6WVW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MTGKDVPGLLEATHAIPAGTKINVTFLGNEDLDMRVTASKAVLEAGFIPVPHISARRLAS
QDQLEEFLGRLQEVGATEHVFAVGGDPAEPEGPYPDSLSVIRSGLLQKYGVREVSIAGYP
EGHPDISSEVLWRHLEDKSAALEEQGLDAVILTQFAFDTDPVMAWIDQVRARGINTQIRI
GTPGPAGIKRLLGFARRFGIGANAMIVKKYGFSLTNLMGTAGPDQFVTDLAGLLAQDASS
GSVKLHFYTFGGLLATSEWARQYAAAQS
>A0A163Z6I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. MIT S9504|TrEMBL
MKGLGSALQRSLEAGAVTVTAEVMPPRGGDPSHTLAMANLLRDWVQAINVTDGSRAVMRM
SSLAVCRLLLDVGLEPVLQMAGRDRNRIGIQADLLGAHALGIRNLLCLTGDSVKAGDQPA
VRPVHELESVRLLQQVSAFNRGEDPVKESLPDGPTALFAGAAADPHCASWSGLKRRLERK
REAGARFVQTQMVMDPQVLERFCREMAAPMEMPVLAGVFLLKSARNASFINQKVPGANIP
DSLIARLDAATDPAAEGIAIAAEQVRQFAGIAHGVHVMAVRAEERIPEVLERAGLSSQQS
>A0A7Z7FIA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia steynii|TrEMBL
MNPIELSFEFFPPKTQEGLDKLRATRAELLPLKPKFVSVTFGAGGSTQQGTLDTVLDMAK
DGLEAAPHLSCIGSSRESLRAILNEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFRIEVAGYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DAHKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VADLCRRLVEAKVPGLHFYTLNGSAATKAICERLVG
>A0A7W8NPV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus metalli|TrEMBL
MTGASGTRVSVELVPRSRSGLRAEIAQVVAALPSVDTVNVPDLTRYSLRSWLGCSFARPR
HRAVPHLRAVDFNPREPLPFLPALGEHGIDEVLVVTGDAPADMSARVYDQDAVDLIRRLR
RDAPHVTVYAGLDPYRQSFARERDYLERKLDAGASGFFTQPFFDLRVMDAYSDLIPDGAQ
MWWGATSILTESSLNYWRARNHAVFPRTFTPTLECNRAFAADLLAFARERGQHAYFMPVK
VDVQAYLEGIL
>A0A7X7CEI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MPGRPTVSFELFPPRGNDLEGVWGRMMRMAEAAPDRFTVTYGASGASREGSEQLIRRLQA
STSIPVLAHVTCVASPRQEVRERVERLMGEGVTDFLALRGDPPADAELQHTADEIPSSVE
LVRLIRQVQAERGIPYVTVAVAAYPSGRHYGPGEFAALAEKQEAGADSAITQVFYDAEAY
AHLVAKAREAGVTIPIVPGILPLTDRSRLRRLFDLTGVAVPATLDALLATEDEDVRLRRG
VDATLALLDRVLAVGAPGVHLYTFNRDHPALDVLAHLRERGLHNPAYLATHKV
>A0A1W1HHI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfamplus magnetovallimortis|TrEMBL
MLRVFNSDITEADNFVVTLELVPGRESTGRSVDTLTEIAKDAFSDGRVSAVSITDNPGGN
PSLSPDALGHEIFRYGMDVIVHFTCRDSNRAGMESRALQLARLGMKNILALTGDYSGRGY
GGQGAPVFDFDSVILTRMLKDLNIRLLESGDPDGFFTGCAVSPFKSTCAESEGQYRKLAL
KVRAGSDFIITQLGYDATLFKELLQQNRNMGIDLPLLASLYMLSPRAAKAMNMGKVPGVV
VTDDLCNRIEKEWQNKKEGLQNAIERTARLGVVLKGMGYRGIHIGGIHKDFETVGKILDR
MDEIENQWQSFLNEFTPSKEQNHAQGEFTPSREQNHSQGELTPTRESGFYQVNLIPDRKC
RNLPHEITLKTLLFDHIPYRFLNMAHGLFFNKSAYSAPMYKKIAEKIETKGFSWIIKRFL
EDPFKKTLLSCRSCGDCGIQHLAFQCPESGCPKHTRNGACGGSRDGFCEVNKDRLCVWVR
SWIRLSRAGSQEKFTSEFVPPRKWELNETSSWINFHLGRDHQG
>A0A1H8L003|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira multiformis|TrEMBL
MESQKKFVPTFSFEFFPPQTAEGIEKLRATRSQLAQLKPKFFSVTFGAGGSTRDRTLETV
LEIQAEGLVAAPHLSCIGATRENIRAMLEQYRSSGIRHLIALRGDLPSGMAQGGEFRYAN
ELVAFIRREYGNAFHIDVASYPEYHPQARTAQEDLRNFKRKIEAGADSAITQYFYNADAY
FDFVDSCEAMGINIPVVPGIMPINRFSQLARFSDTCGAEIPRWIRKRLEGYGDDSASIRA
FGLDVVTDLCSRLLDAGAPGLHFYTLNSAGLTTTVWQRLGL
>A0A1J5SN85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MQDLRASDPVLPVARPGGDLKVSFEFFPPKTDKMQEALWDCVARLAPLAPQFVSVTYGAG
GGTRERTHDTVTRLARETALKPAAHLTCVAASRGEVDEIARRYWDEGIRHIVALRGDPPE
GGRYQPHPQGYAYAADLVAGLKKVADFEISVAAYPETHPDAVSPEADLDNLKRKVEAGAS
RAISQYFFDVDVFLRFRDRAAAAGIAVPIVPGILPVTNFAQVVKFSAACGTRVPAWMADL
FTGLDDDPDTRRLVAATVAAEQCRALVAGGVSEFHFYTLNRADLTYAICHILGVRAKAR
>A0A1M4UTC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactonifactor longoviformis DSM 17459|TrEMBL
MNITELFQRGEFVVSAEVGPPKGTNIDHLVEEAKTYLTGVTAVNVTDNQSSVMRLGSLAT
CKVLKDEGLTPIYQLTCRDRNRIALQSDLLSAAMLGIENLLLLTGDHTKMGDHPQAKPVF
DLDSVSLIHTVKTLESGYDLGGNELVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVMAGA
DYFQTQAVYEPEKFIEFMEKAKQFGKPVQLGIVIPKSVGMARFMNANVAGIHVPESMIDE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAGI
>A0A0M6Y0X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium aggregatum|TrEMBL
MTTCSNRRSHQAAPSPITASFEFFPPKSDKMAETLWQTVQRLAPLSPSFVSVTYGAGGST
RERTHRTVERILKETDLAPAAHLTCVGAARSEIDAIVKDYWDLGVRHLVALRGDPLDGIG
SRYVPHPEGYAYATDLVEGVKKIANFDISVSGYPERHPESGNWQKEIDNLKRKVDAGADR
IITQYFFDNDLFDDYLDRIAAAGINIPVIPGILPIHNFEQTMVFSAKCGTSIPQWLARRF
AGLTNDPETRKLVGVSVACEQVMDLVDRGINDFHFYTMNRADLTFAICHMLGMGQPETKE
TLAA
>A0A4Y8DAX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryotinia calthae|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRALDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDGFEQTLRDHPSGAFKNIPIIPGMMPIQSYQMI
KRTTKLSHAKLPSTIITRLDAVRGDDEMVKRVGVDILSEMVEHLKSTKSQFSGPRGFHFY
TLNLEKAVSFILERSELIPDAETVAALEPEYVPTIPDIADLMSIHSGSHKRSSRRRSSVG
SDPYNRIIITSPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGPKNGFVFQKAFVELFI
PTADWKTLHAKLTSPDLCDTVSFYASNAKGDFISSDEAVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSQTRKIIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLN
>A0A1Y2MY85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia autotrophica|TrEMBL
MTSLLDPPDRSTGPRRTDRRAVLARVLREATYEVLPFPSAGDKVLAHVPTGTGLSVTTTE
AKGLGPTVDLAVRLTGHGYRVAPHIAARLVRDRAHLTDLADRLTEAGISTVFVIGGDAAE
PAGAYPDALALLTDLRAIAGDRFDHIGIGGYPEGHGGIADELIEGALTAKAPYATQIVTQ
LCFDPSATVRWARRIATAGVRLPIRVGVPGAVSRQKLIRVSAGLGLGQSARFLRKQQGML
WRFFTPGGYRPDRVLDGIVPALAAGDTGLAGIHVFTFNDLESTETWRRRLLERLDR
>A0A2N3GRY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium HGW-Actinobacteria-11|TrEMBL
MSSETETSGTPRVPFSFELYPPRSASSEEALHDTVRRLAAAGPDFLSVTYGAGGSTGGRS
LDVLRFIRTQTDVEPLAHLTCVGNSYAGAATLIREFLDAGILSFLALRGDPPTGQTDDDL
GDLESAAQLVQLIDRVQAERAPYEEAPVPGLPGAARVDPRRKVNIAVAAFPKGHPRATHR
TQDVEALLAKQAAGATFAITQLFFHPDDYLAFVERARSAGVTIPILPGIMPITSPARLTR
VLELTGEDLPSELAIALDVEPTAEGRREIGIEWAARLAREVVAGGAPGVHLYAFNQHETV
LTVLAEAGILPALRH
>A0A1R4H0A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenothrix polyspora|TrEMBL
MPSQNNQQMFSFEFYPPKTEEGAANLKIVHNTLSTLNPEFFSVTFGAGGSTRDKTFDTVV
GIQEQGLSAAPHLSCVASTKDNIHSILKNYQDHGIKRIVALRGDVPSGMMSPGEFRYANE
LVEFIRQETGEYFHIHVAAYPEIHPQAHSAADDFKNFKRKVEAGANAAITQYFYNAEAYF
YFVDTCEKNGITIPIIPGIMPITQYTQLFRFSEMCGADIPRWMRKRLESYGDDRTAIQAF
GTELVSKLCQQLLDGGAPGLHFYTMNQSAPTLAIINNLR
>A0A1G6IQN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. YR710|TrEMBL
MRTVSLSKLEEARRALDAPLFADLAGDASVSFEFFPPKTAKMEESLWAAIQTLVPLSPRF
VSVTYGAGGSTRERTHATVARIASETGVAAAAHLTCVDASKVEIEEIARAYWDAGVRHIV
ALRGDPPVAGTKFAPHPEGYRNAADLVAGLKAIAPFEISVAAYPETHPEAVSAASDLDNL
KAKFDAGATRAITQFFFSPEAYFRFCDRAAAAGIDGEIVPGILPVSNVAQTRKFAAMCGA
EIPAWMDRLFEGLDDHPAARQLVAATTAAEMCRRLYAGGVRQFHFYTLNRAELSFAICHL
LGLRADASKLEQAA
>A0A1F7NQ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium RIFCSPLOWO2_02_FULL_68_19|TrEMBL
MAMSPFLSRLAEGPLLCDGAMGTMLYAGGVPLDGCFDVLNANNPTLVQSIHAAYLSAGAD
LIETNTFGANRFKLAVHGLDARVREINARGAKLARDVRETTGREAFVLGSIGPLGKYLAP
IGAIGVEEGRAAFREQAEGLLEGGVDAFIVETFSDLGEIRLAVEAIRALTDELPIIAQMA
FTDEGVTFVGRSAVEVARALRGLPVQVIGANCSVGSSVLYDILEQMLPEAGGLPISIQPN
AGLPSRVGERLIYLSSPAYMAEYAGKMLEAGARIVGGCCGTTPDHIRAMRAAVDRHVPTR
ARAGRVTVSPPAREEAPALRTTAVPTPLARKLEAGEFLVTVELDPPRGHNIEKLVQGAKL
LKERGVEMVDINDGSLGRIRMSVLPTAVLVREATGLDIIMHFTCRDRNLMGIQADLLGAH
AMGIRNILAIKGDPPRAGDYVNATAIFDVNAIGLIRIIQGMNGGLDATGNSIGEPTXXXV
GAGLNPAAVDPDKELARLFRKVEAGARWAQTQPVYDLEVLDRFLSRAGRLPIPIIVGLLP
LHSFRHAEFLHNEVPGITIPDAVRARMKEAGDRALRQGIEMAQALLQQIRARYAGAYLMP
SFGRYEVVAEVLDALR
>A0A1G7EMZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia oroxyli|TrEMBL
MIDRIGARESTGPVFSVEFFPPKDARGEAELWRAIRRLEPLDPAFVSVTYGAGGSSRDRT
IRTTARIASDTTLVPMAHLTAVSHSRAELRHVIGSYAAAGISNVLAVRGDPPGDPLGEWT
AHPEGLTYADELVRLVRESGSFCVGVAAFPYGHPRSADLDADLARLLVKIRAGADFAISQ
LFWEPTGFLRLRDRLAAAGCDAPLIPGIMPLLSAKTMAKGPELSGAPLPAGLAERMAPYA
DDPAGFRAAGLDLTTELCQTLLAEGVRGLHFYTMNRSPATADLVGRLGLGRTAVSA
>U2G5J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter concisus UNSW1|TrEMBL
MLKEKILNKEKGLVLYGLTPPKAEFEEAKLREISERWSGRINDIKADGLVLYEVQDESER
NDSERTFEFSGTLSPEIYYKNYLNVATPSIFYRVASGYGEDEFRAALKAQSSNLNVLVGA
TSSTQKVRLNLARAYEIAGEFEDLAVGGVCIAERHGKKGDEPQRMREKIATGAKFFISQA
IFDEQLARKFLEGCAAANISEPIFLTFSTAGNAKTLEFIKWLGVSVPNSVEERLNSSSDY
LLESCNIIKEIWCELKKFGDENGLNLSINIESVMAKRAEIEASLELTKSIRELV
>A0A651DSX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. DLM2.Bin15|TrEMBL
MSSSNGASSSLAIASRFRRAVQAGEFLITAEVMPPKGGDASRMIAMAAGLKNRVHAVNVT
DGSRAVLRMSSLVASALLHQQGIEPIYQVACRDRNQIALQADLMGAQALGLQNVLALTGD
PIKAGDHPQAKAVFDLESVRLLKLIDRLNQGLDANEKSLPDGATHLFAGAAVDPQSGSWS
GLQRRFERKLAAGAQFFQSQLISDFDRLEKFMDHIAAGSQKPVLAGIFLLKSAKNAEFIN
RNVPGVHIPQHLIDRLAQASNPLQEGMRIAAEQVQLARQLCQGVHMMAIKREDLIPEILD
LAGIAPVSDLGSDLGSDLGSDRPCIQAPAP
>A0A1F4H3V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_66_14|TrEMBL
MERQPNRIPPVSFEFFPPKTPEGVKKLRATWTALACLGPRFFSVTYGAGGSTRDRTLGTV
LEIREAGHEAAPHVSCIGLTRAEIADTLELYRLKNIRHIVALRGDLPSGTAALGELRYAA
ELVAFIRERTGPQFRIEVACYPEFHPQAESPRADLLHFLDKVRAGADGAITQYFYNPDSY
FRFVEDCQAEGVAIPIVPGIMPIGNFTQLVRFSDACGAEIPRWLRLKMDNFSGDLNAVKA
YGLDVVTAMCDRLITQGAPGLHFYTMNRADLVGEILRRLGA
>A0A2N3BUT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HGW-Alphaproteobacteria-6|TrEMBL
MPAPRISFEFFPPQTLDASFRLWETAQMLAPLKPSFVSVTYGAGGTTRKLTHEAVTALHA
NFGLNVAAHLTCVEATRDETLEIAASYAEAGVAEIVALRGDAPQGADRFTAHPDGFASSV
ELIAALADTGRFRIRAGAYPEAHPDAADMAANVAWLKRKIEAGASSAITQFFFEAETFFR
FRDACAAAGIDAPIIPGILPITSWAGAKRFAGRCGTTVPAWLDDAFAHAVRDGREQLLAI
AIATELCDDLLQGGVEDLHFYTLNRPHLTRDICHALGITPEVVLEKVA
>A0A5A9XAI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp. ANT_WB101|TrEMBL
MSGKQAISLEFFPPRDIAAQEKLVRSAKQLLALQPEYVSVTFGAGGSTRSGTADTVRLLQ
NLGCDVAPHLSCIGATRAELAEILNNYRAQGVRRIVALRGDLPSGMGGDAGELHYASELV
AFIREHSADWFQVEVAAYPEMHPQALTATADLEHFNNKVQAGAQGAITQYFFNVDAYFDF
VDRARAAGVSIPIVPGVMPITNYTQLARFSTMCGAEIPRWLRLRLTDFGDDRASIRAFGA
EFIGQLSQALLDRGAPGLHFYTLNNAEATMAIWRQLSLRDTSVAVA
>A0A5B8CW87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methylopumilus universalis|TrEMBL
MAKKISYSFEFFPPNSPEGIKNLKDTRQQLSAFKPEFYSVTFGAGGSTRDRTLETVLEIK
QEGFNAVPHISGISSTKAEIKTLLNLYQQNNIKHIVALRGDVPQGALPSGEFKHANELVS
FIRQETNDYFHIEVAAYPEYHPEAPSAQIDIQNFKNKVDAGANSAITQFFFNADAYFRFM
DECLIADIDVPIIPGVMPIYNINQLARFASNCGAEIPRWLRIKLESYGDDLPSLRSYGVD
VISELCETLIGWDVPSLHFYTLNQAGIISRIIQNIEST
>A0A5N4DC84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Camelus dromedarius|TrEMBL
MDRPKPRVPAVGPCCPSRGMRASEAGSARFSVPPCISRNSAMVNEPRGNGGPNPRSEGSS
SGSESSKESSRCSTPGLDPERHEKLKEKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKQLGLKNILALRGGRRNREATWRLGETQHCDLNPADPIGDQWEEEEGGFNYAADL
VKHIRGEFGDYFDICVAGYPKGHPDAESFEADLMHLKEKVAAGADFIITQLFFEADTFFR
FFKACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYG
IEQAVSLCRELLESGLVPGLHFYTLNREVATMEVLKRLGMWIEDPRRPLPWAISAHPKRR
EEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELL
KMWGKELTSEESVFEVFVRYLSGEPNQDGYKVTCLPWNDEPLAAETSLMKEELLRVNRRG
ILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETTEALLQVLKKYELRVNY
HIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGKL
YEEESPSRMIIQHIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRAPQNEREMEAP
>A0A2W5NF70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum sulfidophilum|TrEMBL
MTETRGALPSLSFEFFPPHSPEASLRLWRSVERLAPLGPRFVSVTYGAGGTTRDRTFAAI
QAILDRARLNVAGHLTCVGATREETLDVARNYARLGVRRIVGLRGDPPKGQTRFTPHPDG
FESAAELVTALRRAGDFEISVAAYPEKHPEAESLESDIANLRRKLEAGASNALTQFFFEN
ADFLRFRDLCAKAGITAPIHPGILPVENFQKMTNFAARCQARVPDWMHAAYEKTSTPEDS
YSLSIELARKQIEALIAEGVDHLHLYTLNNPNLSYDLCVALGYREAPASRAEGGAA
>A0A523HRE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldithrix sp|TrEMBL
MKRRNFLKELENRVILFDGATGTMLYNRGVFINQCFDQVNLTNTRLIKEIHTDYANAGSD
VLQTNTFGANQFKLAQHGLSDSLEAINYQGARLARDVAGNQLFVAGSIGPLGVKIEPWGK
LSRKEAKDAFKEQGQALVNGGVDLFVLETFSDLSEIEQAILALRELGDLPIIAEMTIDES
GNSLYGTATETFTHQLDKWGADVVGINCSVGPPPMMDALEKMVHVTKKPIIIQPNAGNPR
VVDERNMYLASPEYMGEYAMRFIKAGARLVGGCCGTTPEYIKAMEKSVRMLSPRQHNFSI
KVPKEIIEEATPIPWEEKSKFAAKLAKGELVTSVEIVPPRGSDPSKVLESCRQLKEFGVD
GINVPDGPRAMCRMGAQHLSILIEQNVGIETLLHYCCRDRNLLGMQSDIMGLYAVGLRNI
LIITGDPPKMGDYPDATAVFDVDSIGLTNMVDRMNHGIDLGGTKLDAPTGFHIGVGLNPG
ALDPALEIRRFEWKVEAGAEYAITQPVFDPQILLEFLPKIKHVKIPVIAGIWPLVSFRNA
EFMNSEVPGASVPEKYMERMRQAQEISKEEARAEGLRIAQEAVAQSREHVKGFQVSAPFG
KVEYSMQVLSVLKEFGGDV
>A0A844WYN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella sp. Pas-s25|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVSPKDDF
RYASELVTFIKENGDFNVIGACYPEGHLEASTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKAHDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVATLLAVPKTK
>A0A836XJN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Handelsmanbacteria bacterium|TrEMBL
MSQFLTTLQAQPLLGDGALGSYLFERTGRLSEQNHLYETFNLERPDLVRQIHLEYLQAGA
RCITSNTFAANITHLPEAPITELNTEGVRIARQAIDEYRQQTQSQEPFFVLGSLGPTLAM
RESPLEARDIYRQQIEALTGVDALLLETFTSLPHVAAVLEVLQQIPGAPPAIVHMALHKR
GDDWNQDPQIFAKTAADLGAQVLGVNCCTPSEAASFVTCLQDLKLLQDSQVQLSTMPNGG
NFQRIGHRYLTGVNPEYMGRFARSMAQQGVQFIGGCCEVHPNHIREMHNYLHSLTVGEQQ
RTNSVKPAVKPALTLSSTPPADKRQNGSFSRKIIDREFAISVEMLPPRGTGGLKNRLAFI
KELVASRLADALDITDGSRGIPLMPPADFIYLIRQRLDWTTDPIELIPHFTGRDLNVMGL
QSRLIGYWANKIHNVLFVTGYPPKMSPTYPRSTAVFDLDSVALVHFAQAYLNAGLDFGGQ
PLGSHKDPRTRFTIGSGCEPEALDGEREFARLERKIDAGADYIMTQPAFNLEALKNVQEY
RAKVPIVVGVMVLRDLQHARRIAQVPGVTVPEAVFTRLQQYESEADQAQAGIELAAEQAR
WIRREGWAGLYLMSPSSHQPVLEVLKQSRG
>A0A7Y5I2N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudanabaena biceps|TrEMBL
MIEPSQPNFNPSAQFTQFRQAIARKDFLITAEVSPPKGSDPTHMLEQARSLKGRVHAVNI
TDSSRAVMSMSPVAASVLIQQRVGIETICQLACRDRNRIALQGDLFGAAALGITNILALT
GDPVKAGDSPDARSVFDYESVRLLQLIQKLNQGLDANSKLLPHQGTNFLAGAAIDPQSPS
WSGLQKRFERKLNAGAQFFQSQLITDFDRLDKFVHQVANQSDKPILAGIFLIKSAKNALF
LNKFVPGVQIPDHIIDRLAKAKSPLQEGIAIAAEQVQMAQQICQGVHIMAIKAEHLIPEI
LDRAKVSII
>A0A836XJD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Handelsmanbacteria bacterium|TrEMBL
MSLTTLHPPSRYSGAWQKKPLRHMLEETDTFVHIVELVTSRGLITESDGRKVMALARRLA
EHPAFHALSITDNPGGNAMINPDILGTDLISRGQDCIIHISCKDWNRNAIQGRAWQLASE
GFNNILALSGDYPISGYQGTAGGVFDLDSVGLLEMFADMNAGLKMKKGNKTRRMESTAFY
LGVAINNHKRYEREVMPQYFKLAKKIETGAGFAVSQIGYDARKQDELLKYMAMRDLKVPV
IANVYVLSAPTARYFHKGNIPGVEVTDELMAIVEEQAKAEDKGKAFFLELAAKQCAIAKG
LGYRGAYLGGHIAYGDYEKVIEIAGTYTEDDWRDFAKELHFSFPDEFYFFEPADDTGLSS
TDINRAYIASKEKSALREARANLPISYKFNRLTHDRVFATESAGFRLGARLAAALAKRPK
VEKLFHAAEHVLKIAAFDCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTRQGKCEIGE
KDCIWARAYDRLKAYGQEEQMLDGPAVIKDAGLKGTSAWLNTFSHKDHHGKRKESP
>A0A7C1AJK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLEKVLKSGEFAFTGELGPPRGADVEAVRKKVNYLKGFVDCVNITDNQTAMVRMS
SWAASIILVQEGLEPNYQMVCRDRNRLAMQSDILGAYALGIRNVLCLSGDHQQFGDHPQA
KGVFDIDSMQLIGMVKKMRDEGKFLGGDEIKTPPEMFIGAAANPFADPFEWRVYRLAKKI
KSGADFIQTQCIYNMEKMRKWVQQANDMGLTEKVYILAGITPMKSVGMAKYMKNKVPGMD
VPDEVIKRLQGVEKKKQADEGIKMACEQIEEFKEMKGVAGVHLMAIGWEHKVPEIAERAK
VLPRPKL
>A0A6I6DBR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Syntrophocurvum alkaliphilum|TrEMBL
MLSGVFFNILVNICLCNKVFGVDYMKIVEMYESKKPVLSLEIFPPKMDYPLETVFKTLDE
LKKLNPKYISVTYGAGGSNRGRTVEIASRIKNEYKIESLAHLTSIGHSKEEVYSILNELL
NENINNIMALRGDIPGGVQEFDIKNQEYMYASDLIKDINKHSGDFGIAAAAHPDGHPECS
RLSYDLNNLKQKVDSGVDFLTTQLFFDNRIYYDFIEKCTQIGINCPIVPGIMPVLNAKQI
RRIIYLCGASMPAKLLILVDKYENNPEDMQKAGIEYASRQVEDLIKNGVPGVHLYTMNKS
QQIAEIVQNVGLEITTK
>J2VUV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium sp. YR531|TrEMBL
MTKIAASIEVAARQAIESQDLPGLFPAGTRVYITDMGSDSVDTLTSAAKRIHDLGYKPIP
HFASRRLSTKSALETRIRRASEEAGVTDVLVIGGGLERQAGEFSSTMQVLETGFFDKYGI
TEMGVAGHPEGSPEFSEAVALEALRLKKNFGERTGAHLRVVTQFGFDADRFIRYSESLRE
HGVDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNALSLTALATSHSPEGVVGPIE
QHAIANPSSAIKQIHVFPFGGLKKSAEWLTDRGSWDLNTRHFQAANSAAN
>C6BWS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maridesulfovibrio salexigens (strain ATCC 14822 / DSM 2638 / NCIMB 8403 / VKM B-1763)|TrEMBL
MKIIDLINKNGQFISLEFFPPKDRESWPKFFEVVDKLKVLNPLFASVTYGAGGGTQDNSL
EIVKRMKQDAGIEPLAHLTCVGASPENISEFVSALQEADVENILALRGDAPADDKDFDFN
TQTFKHGSDLVTYVKDKHPGVGIAVAGYPEAHLESPSIKEDFKWMKYKIDEGGEFIITQL
FFDNRVYFDFCDRLKGMGIDVPVLPGVLPIMSLKSAKFILSLCGAAIPGKFLSALEKAHA
EGGDEAVYKLGIEFATKQAQELLDGGAPGVHLYTLNRAKACLEIGQALKF
>A0A2H1K4T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MSQEVLASLLKSARYEILPTAGVVDRVHEYVVPGRVITVTASTGLTLEATLSTAEQLQAL
GFTAVPHIAARMVQGRTELEEIVDRLTQAGIDRIFVPAGDATPPAGGYAGALDLIIDLAS
MAAPIQHLGVGAYPETHPLIPDDVTVQAMWDKRDYATHLVSNLCFDPGTIATWLARVRAR
GIDLPLILGIAGKVELAKLARVATKIGVGESTRFLRKNTVTFTKMAKPGGYNPRKFLDKL
SPVLDNPSMGVAGLHIYTFNQIKDTEIWRRRQLAALGHNDEVPSTS
>A0A127B0D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rufibacter sp. DG15C|TrEMBL
MKVTEHLQNATSTLFSFEILPPVKGKSIQSIYEGIDPLMEFNPPFINVTYHREEYVFKER
GNGLLEKITIRKRPGTVGICSAIMNKYKVDTVPHIICGGFSKEDTENALMDLNFLGIDNV
LLLRGDAVKTEAHFRPHTDGHAHASDLIQQVVQLNHGQYLDEEMENPTPTDFCIGVAGYP
EKHVEAPNLATDLKYLKQKVDLGAQYIITQMFFDNKKFCDFVTACREAGITVPIIPGLKP
LTTRNQLTVLPRFFNIDLPEDLVNAVDACKTPQDVKQVGIEWTIQQCKELVNFGVPCLHF
YTMSKSEATAAVARAIF
>G4UIN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neurospora tetrasperma (strain FGSC 2509 / P0656)|TrEMBL
MHIREMLADAERTKAPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIA
ELTCEMVAQAQAYLGLETCMHLTCTDMGEEKVNNALQRAYKAGCTNILALRGDPPREKER
WEAAEGGFQYARDLVAHIRKLYGDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGASF
IVTQMFYDVDNFLRWVKRVRERGITIPIIPGIMPIATYASFIRRANHMNCKIPEEWMAKL
EPVKNDDVAVREIGKTLVAEMCRKIVDAGIRHLHFYTMNLAQATRMVLEELDWLPSPNRP
LKRALPWKQSLGSGRRDEDVRPIFWRNRNKSYITRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNELNRKKWGEPQTVKDIANLFVRYLNQELEYLPWSEAPISSEAELIKDDLIA
LNNRGLITINSQPAVNGVKSTHPVHGWGPANGYVYQKAYLELLVSPELFPEIKRRIEDHP
DITYYAVTKSGNLHTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGLEW
ARCYDADTPSRLLIEDIMNKWYLINIVNNDFHQPRTIFEILNDLSLPDLEKVYTPAHTNG
ATNGVSEASTVPQ
>A0A5Q2MDP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium yanjiei|TrEMBL
MSSATSCPKAMTFGPCGGVRDDASCEIDPRPCPFAGPAADTVRWERELLPSTTPGSALLE
AAEHRPVVLTDLTIPAYDPDGLAEVTRTLADSCDAVLVGEHQNRPDFPPTLMAALIAQAG
GVPWVTLACRDRNRVVLEQELAGLAVAGVDGVLCVTGDGRAQGVRPDVTQVFDLDGTQLA
ALAARAGHAVAVPEAPSAVPQRLRPARLVQKQHAGAHLAVLNHVGTAEEVATFVAASRDL
GLTIPVIAAVALYTDERSARVLQNFPGLHLDPDQVAQVLGAADVRSAGIETALDEARALL
AIDGVAGVNLSGLASGDGALAGAQVKAETGHLIREGA
>A0A233IF87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. V03_P4A6T147|TrEMBL
MGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSAQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASRDELIQIADDYWHNGIQNIVALRGD
IPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQSDLVNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFN
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A542Q1J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SLBN-118|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVAPNFVSVTYGAGGSTRAGTVKA
TEQIAADTTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVRGDPPGDPMGEWVKHP
KGVRYAAELVQLIKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVDKCRAGADYAITQMFF
QPEDYLRLRDRVAAADCRTPIIPEIMPVTSVRQLERFAQLSNATFPADLKERILTVKDDP
AAVRSIGIEYATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGLHEQS
>A0A1B7WBS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabaena sp. MDT14b|TrEMBL
MPDTQSFSAFNNFRKAAQAGDFLITAEVAPPKGADPTHTIEMAATLKGRVHAVNITDGSR
AVMRMSSLVASVILLQHGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPQAKAVFDLEAVRLLQLIRNMNQGFDFNEKPLTDGALDLFAGAAVDPQSQSWSGLQS
RFEKKIAAGAQFFQSQLITDFEILEKFMDKIAVGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEEGMKIAAEQVQIARGLCQGVHLMAVKREDLIAPILDLAGV
EKVS
>D3CZU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. EUN1f|TrEMBL
MTAVGNAARTTARTVAECLASGRTSFSFEFFPPKTAEGERQLWTALREVEALQPSFVSVT
YGAGGSTRDGTIRVTERIATETTLTPIGHLTAVNHSVAELRQVIGGYAGAGVRNVLALRG
DPPGDPQAEWVRHPDGVAYAEDLVRLLRSLGDFCVGVAAFPDKHPRSPDLETDARFLVQK
LDAGADFAITQFFFGADDYFRLVERVRRLGCDAPIIPGVMPVTNVAQIVRMAQLSGAEFP
ADLAARLQAVADDPAAVRAIGIEVATELSERLLAGGAPGIHFITLNRSGATREIYRALNG
>A0A8H4V267|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sp. NRRL 66182|TrEMBL
MHDLGPAFIDVTWGAGGSRSELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALEAAY
HAGCTNILALRGDPPREQEKWEAAEGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDN
SDVDQLIDHLKEKVDAGSTFIVTQMFYDVDNFLSWVEKCRAKGINAAIIPGIMPISTYDA
FMRRSNWTKIRIPPDWLEKLEPVKADDAKVREVGTKLVAEMCRKLLASGHIHHLHFYTMN
LAQATRLILEELRLLPSEESPLHKPLPWRRSLGLRRRSEDVRPIFWRNRNASY
>A0A838FMS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MHIHDIIRSDSPTFSFEFFPPKTPAAAESLYQTIRELEAYMPHFVSVTYGAGGSTRDLTH
DLVERIQTTTKLDPIPHLTCVCHKEEEVQSILQRYAKNSIGNILALGGDPPRGLAYDRAT
DAFQRAADLVTFIRRFNESGEHPDPRGFGIGVAGFPEGHPATPNRLLEMDHLKAKVDAGA
DYIVTQLFFDNRDFYDFRERCQLAGIRVPIIAGIMPITSFSGCKRIAELAGGARFPARLL
RALQRCEQEPEMVTRVGVHFALEQCHDLLDNNVAGIHFYTLNKSDATRTIFDSLGIPRRR
WAEAAAT
>A0A7V2G3X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MHIQDILASHPVSFSFEFFPPKTPEAAEALFRTITDLETLKPAFVSVTYGAGGSTRELTH
DLVLRIKQTTSLNPIPHLTCVCHRRAEVEAILQRYAAAGVGNILALGGDPPRNLAGYRRE
EDDFQHAADLVRFVREFGARGGHPSPRGFGIGVAGFPEGHPGTPNRLQEMDYLKAKVDAG
ADYIVTQLFFDNRDFLDFRDRCELAGIRVPILAGIMPVTSVAGMRRMAELAAGARFPAKL
LRALQRCGDDAGSVSRVGIHYASEQCLDLLDHGVRGIHFYTLNRSDATRQIYANLGLGVS
VAVAGQ
>A0A6L9L2G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma terrae|TrEMBL
MFLEKIKAAESGVMLYGITPPKTGTSPERVTEIAQKTIERLTGLDVDALVVYDVQDESAR
TAEERPFPFITALDPLTFAADYLDALSIPKIIYRPAGKFSNEELSTWLEELHEHNFYPVF
VGVPAPDFPVKTSLSEAYKIWSKHQTTSVIGAVTIPERHNVLNDEDARIVEKMSSGVSYF
ISQCVFNLDYAKRVIEDLALRCSQQQITPPTVIFTLTACGSAKTLHFMEWLGIHVPDDLK
EELKTSEDILEKSVRLCLDIASALTTFCMERSMPFGFNIESVAIRKAEIEASIHMANSIS
QMLKDKGVRKALKVRDESPISQ
>A0A7L6B622|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora ferruginea|TrEMBL
MALGLPSVLPNPQPAIGELVRDGGPTFSFEFFPPKTPAGEKLLWQAIRELEPLLPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWVTHPQGVSYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAAFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTITRSVQLSGAPF
PPALAERFDRVADDPEAVHRLGIEQAGEMCAKLLDEGVPGIHFITLNRSTATREVWQRLR
ADARV
>A0A258BAB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. 32-46-5|TrEMBL
RLQSYGDDTASIRAFGEEVVTDLCDQLLTAGAPGLHFYSLNQADAVLAIADNLSLNK
>A0A1U9RFU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. 'Soap Lake #7'|TrEMBL
MSSQEHPLGISFEFFPPNTDAGRDKLMHVRDELAARNPRFFSVTYGAGGSTQARTRDTVR
SVSQSGITTAPHLSCIGSEKAYLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRTETGDHFEIAVAAYPESHPQTPNFDKDVENFARKMKAGANMAITQYFFTADAYF
HFVEKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWVRKQLESYGDDSDSIAAF
GTDVITRLCERLLDGGAPGLHFYTLNQAAPVLKVVDNLVS
>M5G436|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dacryopinax primogenitus (strain DJM 731)|TrEMBL
MKITKKLQQAEHEGRVWWSFEYFPPRTAPGMQNLLDRIERMRELGPEFIDITWNAGGRTS
ELTSELVRCCQRDLGIETCMHLTCTNMPAAKVDIALKEAKQWGCRNVLALRGDPPFGQEQ
WTKTEDGFEHGIDLVKHIRAGYGDYFDVAVAGFPEAHNRHDREDEMKFLKNKIDAGVDFI
FTQMFWDVDLFIDWVKAVRAAGITCPIVPGIMPIQTWNGFQRATSLAKISTPPALLAALE
PYKNDDEKVREIGTQIVADMCRKILAADIGIRGLHFYTMNLERGTRMLLEALNFVPHIEV
VRPLPWRQALTPTRRGENIRPIFWANRVKSYIHRTENWDEYPNGRFGDSRSPAYGELDGY
GIWIKQTPEEGRQIWGAPQTFNDITELFSKFCLGQLKALPWSDTAPASETTIISTELAKL
NDHGYLTINSQPAVNGAKSTDPVHGWGPRNGYVYQKAYLEFFCDKTKFEELVSRIERDPM
ITYYAIDKHGNLRTNNHSDGPNAVTWGVFAGKEIIQPTIVEAVSFLAWKDEAFELGMQWA
SIYEPGSVSRKLIESMMETFYLVNIVHNDFQNPQAIFGSFGTETKKVVGAVNGNGLSHAI
LN
>A0A835T5T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlamydomonas incerta|TrEMBL
MKLIHKVEEKMKKGETFFSFEFFPPRTEEGVENLFERLDRMVAYGPVFCDITWGAGGSTA
DVTLDIATRMQNLICVETMMHLTCTNMPEEKLESALKEVKKMGVQNILALRGDPPKGQDK
FEAVEGGFNCALDLVKYIRKQHGDYFGICVAGYPEAHPDGIVDDPEQMKKNYLADIAYLK
QKVEAGGDMIVTQLFYDVDIFLQFVKDCRSVGITCPILPGIMPIMTYGGFKRMTGFCKTK
VPAEISDALEAIKDNDEAVKNYGIELGVRMCRQLLASGECPGVHMYTLNLEKSAVAILEQ
LGLIDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSNRPKAYVKRTQDWDSYPAGRWGNTR
SPAYGALSDHQFMRRHSTSEARREKARAAWGAAPATVDDVKQVFVKYINGEVSMLPWSEM
EGGLTAEGAALRDPLAALNANGYLTINSQPRVNGAASDDAVHGWGGPGGYVYGKAYVEFF
CSPEAWETMRAKLDAAPSITYLATTAAGSPSGNMAADAVNAVTWGVFPGKEVIQPTVVCA
PSFAVWKDEAFELWASEWGALYEEGSASRALLAGIKDSWVLVSVVDNDYVGGDLFRVLLG
>A0A7U6KP15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. KH172YL61|TrEMBL
MSSFLQKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALSARSETEIA
PHMSCIGDDKAQIAELLEFYKSLGIRRLVALRGDLPSGQVGMGELPFAVDLVKFIREYSG
DHFHIEVAAYPEMHPQARSFEFDVDNLVNKYRAGANASITQFFYNADSYLYLRDTLEKRG
IDTIAQPLVAGIMPITNSSNLIRFADSCGADIPRYVRKQLADFGDDSKSIREFGFDVVYR
LCERLMSEGVPAMHFYSMNKVEPNKRLVEALGLTV
>A0A3R6NPF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium AF18-31LB|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGKDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKAAEI
>A0A1Y4F732|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. An249|TrEMBL
MKLAEAMKEKMLLSFELFPPKTEKGMANLPGTIEHLSKYNPEYISCTYGAGGGNVGANRE
VCQMIKKAGTIPVTHFTVIRNTKEGIKEQLDQYLEEGVDHMLALRGDIPLGETTTCGDFE
YATDLVKFVKDQYGDKFEIAVAGSPEGHISCRSLDSDIAVLKQKQDNGADYIMTQLCWDM
EQFKRWLDAIRTAGVTMPVDVGIMPILDQAATINMALSRNGCVMDRELSRLISRHWLFPN
PFNPKDAEGKPFDMFYEKKVKEFKEEGIEYTIKQIDEYRALGVNGIHLYALNKWKDVSEI
IDRSGLRTLV
>A8V3W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenivirga sp. 128-5-R1-1|TrEMBL
MKKIHEETSLTVMAHLTCIGHTKKELLDILEDYKNIGIQNILALRGDIPAGQEDFIFPKD
GCKYANELVSLIRENFGDWFSIGVAAYPEGHPESPNLERDIYYFKKKVEAGADFAITQMF
FDNKYFYDYLDLCQKEGINIPIIPGIMPITNFKQIRKFALMCGATIPEYLVKKLEKYQDI
PEEVEKIGIEYAVEQCEDLLKHNVKGLHFYTLNKSKATLQIYNKIKHLIK
>S9RDE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger mucosus DSM 16094|TrEMBL
MALLTFRKRNAPAPMTPGLDSLLTGYSIEVMPRTAEKVEDFRALLPEGTRVYIAHIDGTP
IEDMVATARRLARDGFEVMPHFPARIIPDAATLQDWIARYQGEAGVHQGLVLAGGVAEPR
GAFHSSMQLLETGLFDKAGFDRLHVAGHPEGNRDIDPDGGEETVMQAARWKQDFSERTDA
RMALVTQFAFEAAPVLDWAARLRANGVTLPVHVGLAGPAKLQTLIKFAVACGVGPSLRVL
QKRAMDVTKLVLPYEPTDVARELAARRAADPDFPVEQVHLFPLGGIAKAAEWAEAQGGAA
LRPARRAV
>V5FZ19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Byssochlamys spectabilis (strain No. 5 / NBRC 109023)|TrEMBL
MHIKDKLAEEKASGRPGISFEFFPPKTAQGVQNLYDRMDRMHSWGPAFVDITWGAGGRLS
DLTCEMVNVTQSIYGLETCMHLTCTDMPREKIDAALQAAYKAGCTNILALRGDPPREKET
WEAADGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGCDDNRDVDLLIDHLKEKVDAGSTF
IITQMFYDVDNFINWVEKCRAKGINVPIIPGIMPIQTYAAFIRRSNWTKSRIPPEWLEAL
EPVKNDDAIVREIGTKLVADMCRKLIASGIYHLHFYTMNLAQATRMILEELKLTPSEETP
LHKPLPWRQSLGLRRRGEDVRPIFWRNRNSSYVVRTQEWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSLKDVSDTFIRYIEGSLDRLPWSEAPITAEADAIKSDLID
LNKRGFLTINSQPAVNGAKSSHPVYGWGPKNGYVYQKAYLELLVPPELIDEVIGRIEKNE
DLTYYCISKKGELRSNTSDSPNAVTWGIFASKEVIQPTIVETISFLAWKDEAYRLGEDWA
KCHQPSSPSRKLIQNIMDNWYIVNIVNNDFHKTHDIFDIFKGLSVKNIETEVAPSDDVPA
DAQAGEPTTSN
>A0A1Y4AM49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. An31A|TrEMBL
MNVTDIINRALEERKTRFAFELLPPLKGDGMGGVFGAIDPLMEFDPAYINITFHREGIKQ
TQRPDGGIEWHVVRRRPGTVGISAAIEKRYGVTTVPHLICGGLSKYDIEDALIDMDFLGL
HNVLALRGDKSQNERHFMPHPQGHAHAVDLVRQIAAMNRGEFVDGEVEVCHHSKFSIGVA
GYPETHQEAASPESDIAFLKAKVDAGASYVVTQLFYDNARFFDFVQRCREAGITVPIIPG
IKPLSTVRHLTLLPQTFGCHIPWELEREVLAHRDDAKAVRRIGTEWAIAQSRELKQAGVP
VLHYYPMGKAENIIEIARTIF
>A0A1H0MGI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium limosum|TrEMBL
MTIPEIMKNRMSFSFEVFPPKEEQPLEPLLDTLDHLYAFKPDFISCTYGAGGTNAGRNVE
ICKAIKDSGATIPITHFTCIGNSKDKIRDELRNYLSLGVDHILALRGDFPKGSASTGGDF
DYANELIAFIKEAFPEFSIAMAGDPEKHFEASSFDEDIAHLRIKQDAGADFIMTQLCHDV
AHYEWWVEKIRKAHITLPIDVGIMPVLAKDPTIRMAVSNGSSIPRDLAEIIARYGDNPKD
FKKAGVEYTVKQIHRFISAGIDGLHIYSLNKWADISEIVRAAGIR
>C8ZJ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse)|TrEMBL
MSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKT
LALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVE
AGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
AILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETVANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWET
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKA
WRDEAFSIWSEWAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETDELWEMLLDQA
>A0A0E3SC72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina horonobensis HB-1 = JCM 15518|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRFSASLEDARQLRGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDYPTCGDHPGSKP
VYDLDSVQLIELVRKLDSGIDLAGNKLDGGTSFCAGAVSGIDPEKTMQLIKLEKKVRCGA
DFIQTQAVYDIGTFEEFMEAVNHLEVPVIAGLIPLKSLGMAEFMNKNISGIHVPEEIMLR
MKDASSPLEEGLSIASETIRELTKLSRGVHIMPIGSHKNTPRLLSMAGILKND
>A0A150DI53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDVAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7X7YKU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotogaceae bacterium|TrEMBL
MSERIVDIFENPLPSYSIEVFPPKPNLEKTLEIIFDTIDRLKVIDPSFVSVTYGSGGYNR
ERALSIAGHLIQGAYRALSHITAVGYLRSDIVDLLDQLYYLGVRNVLALRGDIPPNLIFP
DTELDRFRYAYDLIDFVKRDGRFCIGAAAYPEGYADSGDVDLSVLYLKKKAEVGADFFIT
QLFFDNARFYRFLEKARAVGISQPIVPAIMPILRNTNLKRILSLSSTSLPSGLQEKIDRF
GADPLDLEKVGIAHAAKQVQDLREHGMKHIHLYTMNKSKQIIEICRLSETVSKSEGR
>A0A6M8DPP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEADTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEVAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A855NEN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola|TrEMBL
MDPDTPSLASTITDAYSLEVGARDIDELAAAAPRIVRGSTIAIPYLPNQDNDARLAAARR
VRNLGFQPMPHLSARRIGSLDELHTFVRRAVDEAGVERCLVIAGDPPSPIGPFSDSVSLI
DTGVFERSGIQAIAVAGHPEGHPSMPATDRWDVLERKCRSIAERGMAPLIVTQFAFDADI
VLTWLHALRARGIEHPVRVGVAGPAGVAVLARYAAHCGVGACASMLSKYGISIGKLLGTA
GPDRFVDRLATGLSGAHGDISMHFFPFGGIAQSVGWVEQYRSRTARARAD
>A0A0B0P0L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium arboreum|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATSEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNECRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGVKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQYPYGRWGDSRNPS
YGALTDHQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSYCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGTTDVNAVTWGVFPAKEIVQPTVVDPASFMVWKD
EAFEIWSRAWAALYPEGDPSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>A0A0E3WWC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina barkeri 3|TrEMBL
MLFNFREKLNSSKFLVTAEVSPPKGTRFSVPLEDARQLKGIVDAINVTDNQCSIMHMSSL
AFSKFLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICVMTGDFPSCGDHPGSKP
VYDLDSVHLLQLVRKLDSGINFAGDRLDGGTSFCAGAVSGIDPDKPLQLIKLEKKVRSGA
DFIQTQAVYDVGMFEEFMEAISYLEVPVIAGLIPLKSLGMAEFMNRNISGVNVPEEIMFR
IKDSPDPVEEGLLIASETIKELMKLSRGVHIMPVGSHNNTSRLLSMAGLSGK
>A0A2M9X4F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLINKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1G9XFT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. yr247|TrEMBL
MKLDLRAALKRDILTGDGAMGTYLYQMGFPVGISYEELNLLRPETVADVHRRYFEAGARL
IETNTFSANREKLSKYGLEGDVEAINRAGVELARNAVGNDAYVVGAIGSIRAGKRKNVRT
VDVEEALREQIGILLDSPVDGLLLETFYDLEELQLALRIIRSMSELPVICQFANEGTGST
QDGVPLQEAFKRLRDDGADVIGFNCRVGPNGILRSLEKLAPLAGIPFSAFPNAGLPDYVD
GHYTYAATPQYFAESAMRLADLGARIIGGCCGTTPEHIAAVANALQGYVPAAPGTASAQA
VRVIEPAPAKPAPPAVKPSLLEIVKQRKTVIVELDPPRDLDIEKFMQGSKALQDAHVDAI
TMADNSLAVTRMSNLALGYLVQERLSARPLVHIACRDRNMIGTQSHLMGLHALGIDHVLA
VTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFVVGAAFNPNVK
HLDKAIQRLERKIEAGADYIMTQPVYDTKLIEQIYESTKHLNIPIFIGLAPLASGGNAEY
LHNEVPGIRLSDAIRARMNGLKGPEGRAMGVEIAKELLDAAMPYFNGIYLMTPFLAYEMC
VDLTKYVWEKSNRHDFHLYPLSK
>A0A1T1JGE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. MF4640|TrEMBL
MSLLAQYFAQQQFCVLVEYLSAHQTQWSVKTEFAGFPAAMTLADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLKDAKTQGQKNLLLLTGDKLKQHHYSHDLKPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMTAL
QDAHAFLVQHQYAQKILACVMPLTLARAKFMLKHKVAGIVITPHMLQVLQQEKEQGLSDR
VYVRCALQILMCRHLGFAGVHLSACHQPEEQVLLESNIEEYRHLSFAECERLWNTLWQVQ
TGTEFHPKLAYYSRPATSSQIIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDRSRAKQ
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTKILKEKLIPTVSIAVRGTSSWKNWYVEAAS
>A0A495TLD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 1114.5|TrEMBL
MALGIASTRTDRALTVRDLLAAGKRSFSFEFMPPRSEVGEQKLWDAIRRLEPLDPNFVCM
TYGAGGSSRERTVNMVGRIATETTLTPVAHLTAVDHSIAELRNIIGQYADQGVRNVLAVR
GDPPGDPMGEWVTHPEGVTYAYELVELIKGIGDFCVGVAASPNMHPRSTDWDEDIRHFVA
KIRSGADYAITQMFFEVDDYLRLRDRVTAAGCEAPIIPEIMPVTNAKQLERFPQLSGAPF
PADLEARLRAAIDDPAALRAVGMEHATAMAERLLAEGAPGLHFITLNHSTATLEIYQNLG
LHQR
>A0A3D3HP06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morganella sp.|TrEMBL
MSFLHVDQHEALNQNLAELAGRVEVSFEFFPPGTPEMENTLWQSIERLSVLKPKFVSVTY
GANSGERDRTHSVIKGIKEKTGLIAVPHLTCIDATRDELKTIAKDYWDNGIRHIVALRGD
LPDNSRKPDMYAADLVSLLKSVADFDISVAAYPEVHPEARSAQADLINLKKKIDAGADRA
ITQFFFDVSTYLRFRDRCAAAGIDVEIVPGILPVSNFKQLQRFAGMTNVRIPGWLGNMFE
GLDDDPESRKLVGASVAMEMVKILSREGVKDFHFYTLNRAELTYAICHTLGVRPAVACVA
>A0A1L9UCF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus brasiliensis (strain CBS 101740 / IMI 381727 / IBT 21946)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNYQDVQDPARDLPYL
IEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTK
LSHVKLPPQVLAKLDEVKHDDDAVKRIGVDIITDLVHGIRDLVSPGLRGFHFYTLNLEKT
VSFILERCELIPPYTEIDDSDALIDGGNLSAMDSSSYIAPNGVPIRTLASRRSSVSSIPH
NRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEEDSNGLNAETAVIQSELLTLIDKKGWWTLASQPAINGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPNKDYLTVLKPLLQRHGHEKLAWFATNAKGDFESSLPGPNTDDPDPIDIN
PANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPRNSATERFLDDTK
NDVWLVCVVGQEFGAGTEAGSEEEEDEKKWMWRELANCQ
>A0A1F0TB18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC062D07|TrEMBL
MSGQTPSLSFEVFPPNPEVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFINEQAPHFDIIGACYPEGHPDSPNQISDIQNLKRKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAQYIHQATHALFNHQP
>A0A0V1ID42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella pseudospiralis|TrEMBL
MAIILQSALLVCISVYCLMIFFYSNNYVVFFPILCYPTGHPDASSYEEDLLNLKAKVDAG
ADFIITQLFFDEMHYFKFVNDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSKIVIPDSVL
TTLESIKENAEAVRNFEQIGLWKESPVRMLPWKKHPVHSVRCREAVRPIYWNTRPKSYLC
RTRDWKQFPHGRWGDLGNPAFGDLKHYLFSCIDQMNDSCALDMWDKELSSFEHVRDIFCN
FIARTPNRHGHTVRRLPWNENHSDPAVDVLKDELIYYNSNGILTINCQVAVNGLPSNDPI
FGWGEANGYIYQKGYLEFFASSKCTTILLNHVQNFPSINYHAINFDGSFETLNYDEDATM
ALTWGVFVGQEILQPIVANAASFRVWKDEAFDLWQRWARLYESGSIGRKLLQSIHDDHRL
ITLIDNDYPQPCSLSALLRAVIDECCEEKKIDDE
>A0A3S2J131|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.002.02.1.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A4R5PHA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudohoeflea suaedae|TrEMBL
MPTRFDSPTLAGRIKVSFEFFPPKNGDMEGQLWESISRLAPFNPDFVSVTYGAGGSTKQP
TLNTVSRIIKETDLAPAAHLTCVEASRDEVDEVAREFAGAGVKHFVALRGDPSEGVGAKY
RPHPGGYENSAALVGGLRELGDFEISVAAYPEKHPESPDFALDIDLLKRKVDAGATRALT
QFFYDNDAYERYVERVRKAGIFIPIVPGIMPIHNFAQVARFADMCGASVPELLARRFEGL
ENDPETRAMVATAVAAEQVYDLVERGVDEFHFYTMNRAKLVYAICHLLGLRGNGSNGNNG
IHAAA
>A0A136HF38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neptuniibacter sp. Phe_28|TrEMBL
MSLEPYQKISFEFFPPKTEEGRVKLLNVSKTLGQLDPAYFSVTFGAGGSTQQGTIDTVLD
IKQQGFSAAPHLSCVGSTKENIRAILDNYKRNGIDRIVALRGDIPSGTLDVGEFRYANEL
VGFIREETGDHFHIEVAAYPEVHPQAANAQTDLANFKQKVDAGADSAITQYFFNFDAYVR
FVEDCDKLGLNVPIVPGIMPITNYTQLARFSDMCGAEIPRWIRKRLEGFADDRDSIKAFG
TDVVSELSQTLLDFGCPGLHFYSMNQTEASLAICRNLGIDVA
>A0A1M6VWR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia thermophila|TrEMBL
MTVDGGPGRGRRVTERIAVARPTFSVEFFPPKNAAGEVELWQAIRRLEALDPAFVSVTYG
AGGSSRDRTIRAVERIATETTLVPMAHLTVVSHSVAQLRHVIGSYAAAGVPNVLAVRGDP
PGDPLGEWVPHPEGLQYASELVELLRELGDFCVGVAAFPYGHPRSPDPESDLARLVAKFR
AGADFGITQLFFEPEGYLRLRDRLAAAGCTAPVLPGIMPLLSVRTLQRAPELSGAPVPPE
LTAELERYADDPAAFRAAGMEATARLCARLLDEGVPVLHFYTLNRSGATTELVRMLGLAP
ATAAAAAVSG
>A0A838ZEW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moheibacter lacus|TrEMBL
MKVTQHIENAIQQKKPTFSVEILPPTKGNNIQHIFDTLDPLVEFNPAFIDVTYHREEFVY
KKHPNGLLERKSVRKRPGTVAICAAIQNHYKVDAIPHIICGGFDKEDTENALIELNFLGI
DNLLVLRGDPVKSESTFMAEPNGHRYASELLEQIANLNKGKYLDDELENSSKTDFCIGVA
GYPEKHFEAPNLNIDLNYLKKKVDLGAEYIVTQMFFDNKRFFDFVDKCRKIGIEVPIIPG
LKPITTQSQITALPKTFHVDLPDELADELVKAKDNKEVKEIGTEWTINQSKELIENGIPL
IHYYTMSKSDVVVRVLRGVM
>A0A7C7I716|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MPIEAYNDNVFLNCPFDPEYRQIFNAIVFTIYDCGFVARCSLEEDASGDARFAKILDIIA
ECRYSINDISRTELDKSTAVPRFNMPCELGVFIGASMCGASIPPDLDRQLDKCADDDQSA
RALGIEHATKQVEELWANGVPGIHFYVLNRSYSVSKILDNLDLPGHSGRD
>A0A523QNI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
SDPVEPQIIKMEKKVKAGAEFIQTQAVYEPKKFEEFMKATAHLKVPVMVGIVLLKSAGMA
RFMNKNVAGVNVPDNLVEEMDEAEDRAKKSIEIAARLIKEMKSMCQGVHIMAIGWERKVP
EVLDAAGL
>A0A7X3QNB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
METFSDTLSSGEFVVTTELNPPKGTDLGPLMRRAESLSGMVRAFNVTDSAGANMTMAPIG
AAHLMIDRGIEPILQVTGRDRNRIALEGEILAAAALGIRNVLCMSGDPPGRGDHPDAKGV
FDLKAETLLEAVTAMNSGKDMYGNELKGTPTLFAGAVANPGADDVDTELARMEDKVRCGA
SFFQTQAVYDAASFEKFMEGARGFGVPVLAGMIVLKSGGMARILTDKRPGGTGPHSIIDE
MDGAEDRAAAGVRITARLIDEVRGMCDGTHIMAIGWESRIPAILEAAGLAQAA
>A0A7V3H944|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKAVAGHLAVATAESIGRPRVSFEFFPPRTQALEAQLWEAIRKLEPLTPSFVSVTYGAGG
STRDRTHRIVARIVRETTLSPAAHLTCVAASRAEIDNVLRDYRRVGVRHIVALRGDPPGG
VGLPYLQHPQGYANAAELVEAAARIGGFDISVAVHPEKHPASPSLDHEIDNFKRKLALGA
TRGITQFFFDADVFLRFRDRLARAGVYAPVLPGIMPVTNVNGLKKMAEACGASFPRWMIH
LFDGLDDDPETRRLVAAVTTAQLCARLSAEGVRDFHFYTLNRADLALAICRILGVRAKGA
AQ
>A0A6G1ST16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MQHPFIRAVAGGVVLGDGATGTALRARGWRGRNDAAVLHEPALVRQLHEDYIEAGADVIL
TNTFTANRSLLARDGLGDRVRDANFQAAKLARDAREIKGASVFIGGSVGPIGRDLAVGAW
TLAQAAAAFEEQIGALLEGGVDLLVIETMPSLQEALTALRAARAATDIPVIAMVNFNGSL
TSPAGDAPRDIARALTEAGADLAGVNCGVGPQAALGMLEAMAGHEAFAPLAVKPNAGLPR
VAGDQLVYPSTPAYFADFALRAKDLGVAFIGGCCGTTPEHIAAARRALRGPAVEVAPPAT
RWLPLGETVDTRGSVAAAEELGGEAEPIAKREHARLRDKLAAGKYVISVEIDPPRGINPR
KAVEGARELHEAGADAINIGDSPMARVRMSALSLAVQIERQVGIETIIHQTTRDRNLMAL
QSDLLGAHALGIRNIIALTGDPPPEASQSSAVWDVDAIGFIHVLKRLNAGVDFAGNSIGR
ATDFFVACAANPTADDVDLELRRVRQKLDAGADLLMTQPAYDQATVREFFERLGPIEVPV
LLGVLPLMSSRHAEFIHNELAGVVVPAPIRDRMRAAGEAGAAAGLEVALEHVKETRTLDF
VSGIYIMPSFGRYEVAAEMVRRIAAGEGEGAGG
>A0A7X5TLB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus stackebrandtii|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTVEMEKTLWKSIGRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWNNGIRHIVALRGD
LPDNSEKPKMYGADLVELLKKEADFDISVAAYPEVHPEAKNSQADLISLKRKIDAGANRA
ITQFFFDVEGYLRFRDRCVAAGIDVEIVPGILPVSNFRQLKRFATMTNVRIPSWMTRMFE
GLDDDPESSNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A6N4EH49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospira oryzae|TrEMBL
MFFNKIKQRESGILLYGITPPKATMPLEKVQSAADKSLDLLCAMDIDALIVYDVQDESAR
TNEERPFPFSSALDPFEYTSRYLQRLTIPKIIYRPAGKFSKEELTQWLHQLSTNNFYPVF
VGLPSPDFVVKTSLKEAYDIWRTHHEHHSVIGAVTIPERHALLKDEDVRMMDKVSSGVSY
FISQCIFNVDYTKQTLQALVDNCQSCQKELPTVIFTLTICGSAKTLDFMEWLGIHVPDDI
KAELKVIENPAARSVEIATAIANDLISYCQQNQIPFGFNIESVAVRREEVEASIELLKTV
DQLLKINGLRTAAKKEGIASKV
>A0A524H7G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKLQEALAKRKFVVTAEIAPPKGTDVAEVTEMGKKLKRWVHAVNVTDQQSSTMRLGSMAV
CHLLQEQGVDTIYQLTCRDRNRIALQSDLLSAHVLGLRNVLALTGDLPELGDHYQAKQVY
DIDSVHLLEAIAKLNDGFDMAGNPLKGKTELFPGAVVNPGADTEAAYELQLIKFEKKVEA
GAKFFQTQAIFDVETLNRFMKRVSRYNVPILAGIVPLKSAGMARFMNMNIPGIHVPDNLI
QQMAQSEDEERTGNCIAGNLVRQFKPYCQGVHLMTIGRAEKVPAILKVAGL
>A0A419DF25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MRIGELLKKRGKSLSFEFFPPKEDLGEVNLFESIHSLESFKPTFVSVTYGAGGGTLKNTR
HIAERIIEETSLNPMPHLTCINQSREELEAILNDYKMMGIDNILALRGDPPANKDGSPPV
QKGKYFARDLVRWVESVGGYSIGVAVYPEGHGESPDLERDMLYTKEKIDAGADFAITQMF
FDNRFFYNFMERSEKVGIRIPIIAAIMPITDVSRIQQFCQRCGASLPDACIKRFGDKPLT
KQEAIQIGIELASEQCADLMKNGVNYFHFYTLNKDESVAGIIRNLGLQKLGMD
>A0A4R2VHM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PP-CC-3G-465|TrEMBL
MSTRTLYPAERGDLRLSFEYFPPKSDEMDAQLTRTAAALNAYTPEFVSVTYGAGGSTKAR
SLTTVRRLLDDCAIPGTAAHLTCVGATRAEVDAVVEEFAAAGVRHFVALRGDPQGGIGAQ
YQPFPDGYENAAALVAALSRSGRFQISVSAYPEKHPESSDVDADIDMLKRKVDNGATRAL
TQFFFDNNDFERYLERVRKAGISIPVVPGILPINQFGQVSKFAGLCGARIPEALSARLAH
LDESPEERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFKRTDEAVVE
GAAA
>A0A4V1N2D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium amnicola|TrEMBL
MKVTQHIENANGKPLFSFEILPPLKGQNIQSIYDGIDPLMEFKPPFIDVTYHREEYEFKE
LENGLLQKKIVKKRPGTVGICAGIQNKYDVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPDKDGHAYASELVSQISNLNNGIYLDADLQNTNQTNFCIGVAGY
PEKHMEAPSVDSDIHFLKQKIKNGAEYIITQMFFDNQRFFDYVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNEAVKQIGIEWCIAQSKELVKAGIPVLH
YYSMGKAENIKAIAKEVF
>A0A1E1GC77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. NPS 308|TrEMBL
MSRQTPSLSFEVFPPNPEVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFITEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQP
>A0A2W4NSL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKIIDKLGSTPAFSFEFFPPKGPEGMETLFETVARLRAYDPTFVSVTYGAGGSTRRLTVE
LVQRIKREAGLETMAHLTCVGARREDIAGVLDELTRGGIENVIALRGDPPRGQTTFVKPE
GGFSHASELITFIREKYDFCIAGACYPEKHPEAPSFEEDLEHTLEKVRAGADFLITQLFF
EPRDYFRFVERARAIGITVPIIPGVMPITNVSQVKRFTAMCGATIPPRLLEKLEAHAEDT
EAVQRIGVEHATWQCRELLQGGAPGIHFYTLNRSRATVDILDRLR
>A0A387B323|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Protaetiibacter intestinalis|TrEMBL
MTAAAPAACPTFSFELFPPRDAAAEAALVGSALPALVAAGPEFISVTYGASGSTRGVSLD
VLRRLLATPVKPMAHLTCVGSSYAEASRLIREFLDAGVTSFLALRGDPPAGVPEEEIFLG
DLGSAGELVQLIHRVQKERVPFRQVELPGLPGAKRIASGEKVTIAVAAFPNGHPRSRSRA
QDLDTLLAKEAAGANLAITQLFFEADEFHAFVADARAAGVTMRILPGIMPMLSVPRLRRI
LELTGEREPTALLRALEASDDPFSVGVDHAIRLGRALLDGGAPGLHLYTFNRHEAPLAVL
DGAGLLPLTTPTGKTS
>A0A4V2B5B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSENTYSLELFPPKTPEGAQKLRATRAELAQLHPRYFSVTFGAGGSTQSGTRDTVLEISA
EGHDAAPHLSCIGRNRDELRTMLREYQSHGIRRVVALRGGCRGTGTRAT
>A0A4R1PZN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azotobacter chroococcum|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMTVARQLAGYDPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRSLLNTYQDAGIRRIVALRGDLPSGMGMASGELRHASDL
VAFIRAETGEHFHIEVAAYPEMHPQARNFEDDLRHFAAKMQAGANSAITQYFFNADSYFH
FVERVRKLGVEQPIVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFG
EQVVTEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLPR
>A0A372LYC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces triticagri|TrEMBL
MALGNASTRTDRALTVRDLLATGKTSYSFEFWAPKTPKGERNLWNALRRVEAVQPSFVSV
TYGAGGSTRAGTVKATQQIAADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDTDVRYFVD
KCRAGADYAITQMFFDAEAYLRLRDRLSAAGCDTPVIPEVMPVTSVRQLERFAELSNAAF
PADVKERILTAKDDAAAVRSIGIEFATEFCAKLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPTQV
>A0A418VG98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas palustris|TrEMBL
MTDLLPHPPAISFEFFPPRSEEMERNLWQAISRLAPLAPRFVSVTYGAGGSTRERTHSTI
ARILQETSLTPAAHLTCVDAPCADVDDVVERYHEVGVRHIVALRGDPSSGLGGAYCPHPQ
GYRSSADLVASIKRRHPDIDVTVSAYPEKHPESASFDADLDMLEAKVDAGASRAITQFFF
DNDLYFRYLDRVRARGINIPIVPGILPVQNFKQASNFATRAGASVPDWLAKQFEGLDDDP
DTRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGLRPQTARQAA
>A0A2N6VKI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium paucivorans|TrEMBL
MTTLSASAPLDTHTSGPSAGTTLVGASQEKPGQQPESRLALSFEVMPPRSAEQQERSGEL
LDLLASYDPDYVAVTSAVRTGWSAGTAAFISQLSATTRLRPLAHLACTAAPRDELVTWIE
RYIDSGVRGFLAIRGDLAPGATAPPAGHLAHADALVTLLRSVERNQVARLCAGRFAIGVA
AYPSGHPESKRPEEDIDVLAAKQRNGADFAITQLFFNPAQITTMSRRADLAGVTLPIIPG
IMPITGSARLTRMCQLSGLTPPAYIAQALAAAGSPAEEYETGLNLTADFVEALVAVGVPG
LHFYTFNDPTTITELLSRLSPQTRARLTNNRKDTP
>A0A811XK50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter europaeus|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7H5JRX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S1A1-3|TrEMBL
MALGSASTRTDRARTVRDMLGTGKATYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDVDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCTTPVIPEVMPVTSVKMLERLPKLSNASF
PDVLKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A7Z7PW38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciceribacter naphthalenivorans|TrEMBL
MSPDFNPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGASAMGV
QNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLSTPPHVFLGAA
INPFAPPYDFRPYRLAKKIESGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PLASAKTAKWIRSNVPGIHIPDSVIKRLEGAEDQKREGKQLCIDIINEVKEIEGISGMHV
MAYRQEEYVAEIVHESGVLKGRKPWRREANPGDALVAERLEHIREEKVEDQQQMAGLAAH
LNPKNSH
>M3VU14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Felis catus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEASSGRFSVPPSISRNPAMVNEPRGDGGPTSRSEGSS
SGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCCQSQEQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDVCVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMWGEELTGEESVFEVFACYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A352NG09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelotomaculum sp|TrEMBL
MKLLSKLQAVLEGGHFAVTTEIGPPKHAGTHGLKYTAQILKDFVDAANITDNQTAIVRLS
SIAAGVHLLAGDLEPVAQMTCRDRNRIAIQSDLLGAYSLGMRNLLCISGDHQQFGNHPTA
KNVYDLDSIQLVNLMSRMRDEKKFFCGEEIKECEPRFFIGAVANPFADPFEYRVDRLEKK
IQAGAQFIQTQAVFDMERFERFMELVRARGLDQRAHILAGVIPLKSWRAAKFMQTQVAGM
IVPDALVDRLKNAVDPQSEGVALCIEQIKHIRENIKGVHGVHIMAIAREDIVPGIVKQAG
LYPRP
>S7ZD18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium oxalicum (strain 114-2 / CGMCC 5302)|TrEMBL
MHIRDMLASKEAAGEPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGHLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDQALQSAYKAGCTNILALRGDPPRDKET
WEATENGFRYAKDLVRYIREKYGNHFDIGVGGYPEGADDNSDVDQLIDHLKEKVDAGSSF
IITQMFYDVDNFIEWVKKCRAKGISVPIIPGIMPIQQYASFIRRSNWTKTRVPPEWMKAL
EPVKNDDAAVREVGKRLIADMCRKVMASGINHLHFYTMNLAQATKLVLEELGLAPSEEAP
IQRALPWRPSLALGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGEVDA
YGVRLKGTNEQNIKLWGEPKSVKDLSDIFIRFLEGKLDRLPWSDSPISPEANDIKDLLID
LNRRGFLTINSQPAVNGVKSSHPIYGWGPKNGFVYQKAYLELLVPPSLIDELISRIERND
DLTYHAIRKNGELRTNTNDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYRLGEDWS
KCHDSSSPSRKLIQEVVDDWYLVNIVDNDFHRNNAVFELFKELEVPELNVEFTGKLANNG
SAKQNGSANGH
>A0A081JDR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia sp. 670|TrEMBL
MSFPISFEFFPTKTPEGATKHVQVRKNLYARKPQFCSVTYGAGGSTQTGTFAMVRDIQNE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPQSDLDAFAAKVRAGADSAITQYFYNADAYGRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A249PTX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium fredii CCBAU 83666|TrEMBL
MSPDINPFDPSAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHEATPTETLVAERLGHLREGIEENQQQLAEAAAH
HPH
>A0A2N1W0T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium HGW-Ignavibacteriae-2|TrEMBL
MKVIEHLAKAKDTVISFEIIPPKRGGDIKQLMNVLDDIIKYDPPFIDITSHAAEVYYEET
APGDFKMRIKRKRPGTLGICALIQNKYNVDAVPHVICQGFTREETEDFLIELHFLGIDNV
LAIRGDDSGFHKPIKFGRSTNSFAIDLIKQITDINHGKYIEDSLLDAKPMDFCIGSSGYP
EKHFEAPNLETDIQFTKTKIDAGAEYIVSQMFLDNSKFYNYRNKCEQAGIKSPIIPGLKI
LTTKSHIHNLPKNFHIDVPNDLASEVMEAKPEHVIEIGVEWAVKQVEDLLNNNVPAIHFY
IMQNSDPIKKLMSKLKL
>A0A1G3QER3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium RBG_13_51_14|TrEMBL
MGLINNMGNKFLICADIDPPKGIDTTSLFRTADLLKGRIDALIVNDMPSAVMRMGSLAAS
YLLKERGFDTICNITCRDRNVLALQSDILSAASLGLENIYITRGDDITFGDHPRAKPVNE
LDDDQLLTVLGRLKEGTDAGGNKLNSAPQLNIGVAMQYDPAGNSPDQQIEIMNDKIARGA
AFFIAPPVFDLNAFEKFATKTRGKVRAPILAEIIILKSVATARYINKHIQGITVPDRYID
RLYSAPDKQKESIAIAAELIKGLKKLCSGVSIKAMGWEDKIPSYLDAVEA
>A0A268TJQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. 11S02629-2|TrEMBL
MNIESFLKDLKNQAKQTITYELSPDKSASLDSLATKVLESKLLNHIDGFVCTDSPLAKMR
QSSLLSSIKFQALFNKPVVCTTSLRDRNSLALSSMMLGAHSFDIRLFLALSGDALKLGDQ
PQAKSVFEGSSLKILELINALNKGFDLGGNPLKHPLVTPIYAFSTISSYAKNKTLLKKSL
ESKIALGTKAIITQPVYDIETLKELLEWVDEINAKYSTDAILIFGFFPVLSLKSAIYLNT
KLPGVFVPESLIVKMEEASLSGSEKEVGFELSLKLLESLLGLHKKCHFMNGNNANLASSM
LASIK
>K9D2L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella seminalis ACS-216-V-Col6b|TrEMBL
MVTSLHEKHQAGQFTITVELDPPKSASVNKTFKEAAQLLDKVDAINIADCPMAKLRMSPI
ALAHLIKFRAQIDTIFHLTCRDRNILGLQAELLGAAALGVNNILTLTGDEPSRGDHPDAK
PVFEVDSIGLLKIANTLNNGFDLAGNPLDESTNFYIGTTGNPGADDLDAEKAKIIRKIEA
GANFIQTQPIYDLEKAKRFVDMVEPLGLPVMLGLIPLKSFKMATYLHTKVPGIFLTDDIL
NRMEKGGKEAGLEIALETLLAIKQIAHGVHIMPLNDIQTVLYLIDHIS
>E5VIR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 5_1_63FAA|TrEMBL
MKISEILKNKSTISFEVFPPKNKEGNISSIYSTIEGLAKLSPDFISVTYGAGGSTKGKTV
EIASVIKHEYGIESVAHLSCISSTKEDIKYECERLKEAGIDNILALRGDYPADATNFDPE
NLEFHYASELNEFIGEHFKGQFCLSGACYPETHQEADGFKKDLEALKKKVDAGAEYLVTQ
IFFDNDYYYRLVREARKIGITVPILAGIMPITNAKSLIRTTKMCGCTIPYQLSTMIEAHY
DNPEAMKEIGINYAAQQIIDLITNGVDGIHIYTMNRAETAQRVFDSIPAVLKELN
>A0A6I1YXE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. RB17|TrEMBL
MNPALTVTPAVGAALLDDFSLEMTGKDVPRLEEAQGSIPRGTRINITFLAGEDLGMRLAA
ARAVKRLGFVPVPHISARRLPSRAALEEFLSGLAEDGTAENVFVVGGDPARPEGPYPDAL
AVLRTGLLQRHGVRHIGISGYPEGHPAIADGTLWSALTDKAAAIGAHRFGGDVITQFGFD
VDPVLGWLEAARARGVHLPVRIGVPGPAGVRRLLGYATRFGVATSASVARKYGFSLTNLM
GTTGPDRFLHALARRYDPELHGVVKLHFYTFGGLRHTAEWITGFRQATALGTPAP
>A0A7Y9THE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulicella arctica|TrEMBL
MTKVGAGHTEVERLFQGGTAERNASATRHTVLCDGAMGTMLYSHGVFINRCYDELNLSQP
EMVHDVHHEYLQAGAQVIETNTFGGNRFRLERYGLANRVRDINLAGVRIARACVNQMREK
QASEAFVAGAIGPLGIRLEPLGKTGLDEAFDAFAEQVKALVEDGPGTGADILIIETMPSM
TETEQAILAARSEAPGIPLIVMVTVDEDGNCLDGTTPEKAAAQMTQWGADAVGCNCSAGP
ATVLSVIERMRSATHLPLAAMPNAGIPRAVDGRTIYMTSPEYMASFARKFIRAGATFVGG
CCGTTPNHTRAMRSALRAQSVQDAATQEASVSVGTEKSSAPEGKDSVEPPPLGQRSRIGA
KIAVGDFVTMVEIVSPRGIDCSKEISGAAQLHQLGVDAINVPDSPRASARMSAQSLCVQI
QQNVGIETILHYTCRDRNVLSMQSDLLGASSIGLKNVLCLTGDPPKLGNYPDATAVFDVD
AIGLVNIVRNLNHGLDIGKNPIGESTGFTISVAANPGVPDIENEIRRFAFKVEAGAEFAI
TQPVFDMRLLEEFLRRIEGFRIPVIAGIWPLTSLRNAEFMKNDLRVSMPEAVMTRMGAAA
SPELARAEGIKIAQEMLAEARPMVQGVQVSAPFGKYAAAAQVLGLVESVEA
>A0A7U9Q1F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces chrestomyceticus JCM 4735|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWIQHPEGVLYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCGTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEGSPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A7Y0AU84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. S-51|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPHDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRSMRDESKFLSGRKLTSPPQVFLGAA
INPFAPPYDFRPYRLAKKIQAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PLASAKTAKWIRSNVPGIHIPDAVIKRLEGAEDQKKEGKQLCIDIINEVKEIEGVSGMHV
MAYRQEEYVAEIVHESGVLKGRKPWKREANPVDQLVAERLEQIREEKVEDQQQLAGIAAQ
HPH
>U6FNW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus CIRM-BIA 101|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSEEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHRS
>A0A438CEJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vitis vinifera|TrEMBL
MKIIEKIREAAEVGKAVFSLEFFPPETEDGVDNLLERMDRMAKHIRARYGDYFSITVAGY
PDLIITQLFYDTDIVLKFVNGSHQIGITCPIVPGIMPINNSKGFLGMTGFCKTKVGKVDD
VETLDSGFGCADKSDVGVEGFPERNFHSWVPVQGVDSRSNFTIFCQRFGTLQYLPRWLSL
TGRQWENSDDRHDGLVT
>A0A424TQL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium TMED7|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPGNEKMEXTXWKSVERLAPLXPAYMSVTYGA
NSGERDRTHDVVXRIQXQTGVTAAPHLTXVDATADXLXQIARDYWDSGIRRIVALRGDLP
KGVEXTDMYASDXVALLKXVHDFDISVAAYPXKHPEAPNAQFDLLNLXRKAEAGASEAXT
QFFXDTGVFXRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKLYEGX
DADDQTTRNLLGANIAMEQVKVLAKEGVKHFXFXTLNRSXLSXAXCHMLGVKPQNXGXXA
XLXRGX
>A0A0V1CY75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella britovi|TrEMBL
MPALLMPSVPKGMSNIFVFTYGLLYNMNSTYNLQVKLKSPAYQRAVTVAKVGNPSQQTDF
GVYFEEDSFLSLMASLEAVELKATRHDLNSAAKKSTDEIYRPLIDRIKENISSGRRFFSL
EFFPPHTTEGLINLLKRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCILNFCLL
DTMLHITSVQYDEKTVLFNLERAKKIGIRNILALRGDISDDANVTTTDFQYACQLVRFIR
SHYGDYFTICVADAGADFIITQLFFNEMHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIM
KIVQLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRKLLNREHHVVPGLHFYTLN
QEKSILEQIGFWKKVPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYLCRTRDWKQFPH
SRWGDVGNPAFGDLKHYLFSSIDQMDDSCALDMWDKELSTLEHVRDIFCNFIARTPNRHG
HSVRRLPWNENHLDPAADVLKNELIYYNSNGILTINCQAAVNGLPSSDPIFGWGEANGYI
YQKGYLEFFASSTCTTILLNHVQNFPSINYHAINFDGSFETFNYDEDATVALTWGVFVGQ
EIVQPTVANAASFRVWKDEAFDLWQRWAGLYESGSIGRKLLQRIHDDYRLITLIDNDYPQ
PCSLSALLRAVISDYIGGKNLTTDDDRLALFSLVLPN
>A0A2B7YXL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emmonsia crescens|TrEMBL
MEKISDKIAALPRDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDDALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTYAVDLVKYIRRAHGDHFCIGVAAYPEGHSDESYPEVQDPARDLPYL
VEKTKAGADFIMTQLTYDLEAYKRFEEMLRNHESGVFKTIPIITGLMPIQSYHILSRTTK
LSHARVPPDIMARVEKVKSDDEAVKRIGVDILCEIVNGIKKIPCPGPRGLHFYTLNLEKA
VAFTVEKCNLIPTSSEPSSDSDTDLDSAVVIAQGKQNGIPLISKRRASSMNSQPHNRLIV
DRPSDAGGSSQASTTHETQALGAGMPALNPPHRTTTLQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVNATVARRLWGYPTMKQDINNIFQRHISGELHIVPWSEGGT
QDTGGLNPETATIRDELLQLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAF
VEFFCPSHDFETILKPIFESHDHDELAWFAMNATGDFQSSSGPTDSIADDYSGPVDVFLD
SNATGSNTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIFPRGSPTER
LLDQLKNDVWLVCAVGQKYGAGCESKEAADAEGKLLWKLLGEKDTEADSANTH
>C6CZ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. (strain JDR-2)|TrEMBL
MLKDKILNRQAGIITYGMTPPKSSHTPEKLAEISEKQYERLKNLDIDGLILYDVQDEADR
TDEERPFPYLEALDPTSYSKNYLNYWKVPKIIYRVVGNNSEESFAEWLKQDAEEDRFSVF
VGTSSSKQQTTMKLPEAYELSKKLNDRLTLGGVVIPERHMKKNDEHLRIRDKVDGGCKFF
ISQATFNVEASKNMLSDYYYYCQEQGIETVPILFNLAPCGSQKTLEFMKWLGISIPKWLE
NDLIKSTDILDKSVALSLKIFEELFEFGIEKGIPIGCSIESVSTRKVEIEASVQLVKDIK
NMIDRKLGVHAIV
>A0A2S8K6J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium SEEP-SAG9|TrEMBL
MRVTDLWKKKKQPTISFELFPARNEKAAEQLEKVIDDLVTLEPDFVSVTFGAGGSTREGS
RQLLDKLKNDKGLEVVAYFAGYGLGPDDIRSVLDSYKALGIETILAVRGDPPHDDKTFEL
HPDSFPYASDILAFIKSDYDFCMGCAGYPEGHIDAETKGKDLEYLKLKVDNGAQYIITNY
CYDNQYFLDFVDRCKTIGIDVPVVPGVMPIYSVKMMEMLANLCGATIIDKVRNGLAALPP
DDKAAVANFGIDFATQQCRELIEQGVPGLHIYTMDRSKASLEIIKRLKEEGML
>A0A367A858|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. TF02A-30|TrEMBL
MPVPSVPVTQTVRELLASQRPTLSFEFFPPKTPEAEPQLWTALRELERLQPSFVSVTYGA
GGSTREGTVSVTERIATETTMTPMAHLTAVDHSTAELRHVVSRLAAAGVRNIMALRGDPP
GADPQAEWVAHPEGLSYAAELVELIRSMGDFSVGVAAFPERHPRSPDFDTDVEMFVAKCR
AGADFAITQMFFRAEDYLRMRDRVVARGCDVPIVAGVMPVTNARQITRIVQLSGQAFPAE
LAERFAELDGDRPEDKAAVRAYGVEVATELCRTLLDEGVPGIHFITMNRSTATREVYANL
AATVPEVVPVTPAR
>A0A1K1T147|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis australiensis|TrEMBL
MTSVIERLRGDGPKFSIEFFPPRDPADEAVLWKAIRELEPYDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYASVGVRNILALRGDPPGDVYGEWI
PHPEGLTYAEELVQLVRSLGDFCVGVSAYTYGHPRSPDLESDTKYLVRKLRAGADFAIAQ
LFHDAEDFLRLRDRVAATGCEVPVLPGVMPLTTMRTLQTTIRLSGAPAPRKLLDRLEPLA
DDPKAFRAAGIDVITELCEKLIAEGVPNLHFYTFNRSKATREVIARLGLVPARA
>A0A1H0KGD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klenkia soli|TrEMBL
MTHGPCGGVAEDGRCEVAPVPCSFLPLPTMRWSGPTAVRTAPEPRLLALMRQRPVVVADL
PAVALDRASLERSADVVVGHVDAVLLGDHGAARVQFSPTYRASVVQARGLPVWQGLNCRD
RNRVALEGELAGLADLGVGAVHCVTGDHTATGDRPDARPVFDWDSTQLAAAARAAGVLVS
VGETPHGPPAERRPHRLVEKVRAGADVCFVNHTGSVQELRDFVERATDAGADVPFVACVA
VATDPGSVAELRRFTGLRLPAGYLAGIESAHDPARAGIAAATALAEEYLAVPGVRGVDLS
GVAAPGTELTTATALAEIGRRLS
>S5VKS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces collinus (strain DSM 40733 / Tue 365)|TrEMBL
MRDILATGKTTYSFEFYAPKTPKGEKSLWNALRRVEAVAPDFVSVTYGAGGSTRATTVKE
TQQIVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWVPHP
RGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSTDADTDVAHFVDKCRAGADYAITQMFF
QPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPRLSNAHFPDALKERILTAKDDA
AAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>A0A2W5N240|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micavibrio aeruginosavorus|TrEMBL
MTNPSISFEFFPPKSEKSAQDLVATVKELACYNPKFMTVTFGTGGGSRDGTLQTLKNLQR
AAPDVAFGSHLTYISHTKDELDHYTDMLWNQGIRHLVALRGDMPQNLVWPLDPDAGYYQF
TSDFVEALMKRHPFDISVGAYPEKHPDAPSLDADLIALKKKCDAGATRAITQLFFDNDVF
YRFVDCTQKAGITTPIVPGLLPIRDFQKVCEFAAKCQASVPQFLHDKFANAVSDTMAEDL
LSAQVEDLIRNGVDHIHFYTLNKSSVINSVCSTFSPQ
>M6EBV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira sp. serovar Kenya str. Sh9|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTQDGDLKLMGTVKELARLDPDFVTVTYGAGGSTRDK
TAQILSEISKNYSFPTVSHFTCVGANQDQIFKTLKEIRSSGIVNLMALRGDPPKGEGKFK
KTEGGFENATELISFIRSEKLDFCIGGGCYPEKHPNAKSLEEDVRNLKRKVDAGTDFLVS
QLFFVNSIFENFLNLVRKADIRVPVIPGIMPITSFSQIERFRSIAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSIKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>B9NMM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium KLH11|TrEMBL
MTKPEISFEFFPPQTLEASFRLWDTVQTLAPLNPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLQVAAHLTCVDASRQETLEIADTFARAGVQDIVALRGDPPKGQDQFTPHPEGFANSV
ELISALAETEMFSIRVGAYPDVHPEARNATADVDWLKAKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGILPIENWKGARNFAKRCGTHIPEWVENAFEKAVRDDREDLLAT
ALCTELCSDLIEGGVDKLHFYTLNRPELTRDVCFALGITPRTELQNVA
>A0A1H4FQ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes timonensis JC136|TrEMBL
MNVVDIINEAVAAGRTRFAFELLPPLKGDGMQKIFAAVEPLMALDPAYVNITFHREGIKE
TEREDGSIEWHVVRRRPGTVGISAAIQHRYGVEVVPHLICGGLSKYDIEDTLIDMDFLGL
HNVLALRGDKSQNEKRFMPHPQGHAHAVDLVRQIADMNRGKFIDGEVEECHHSKFSIGVA
GYPEVHAEARDITSDIVRLKAKIDAGAEYVVTQMFFDNCKYFDFVRRCREAGIDVPIIPG
IKPISTLRHLEILPETFGVELPEELVREAKAHPDDVREVGTEWAIAQSRELMAAGVPVLH
YYTMSRTTNIQKIVNTIF
>A0A416A9T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. AF48-14|TrEMBL
MKVIDLINNSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSIQKVNIRKRPGSVAIASAIQNKYNITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTIEAGQNTDLYHEHATDLQEQVNNFNKGIALDGSRFEANETPYSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDEEAKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVYKVAKEVY
>E8JNU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus equinus ATCC 9812|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLIHPEKVSAIHKAYIEAGADVIQT
NTYAAKRHRLKGYGYEDKVKEINQAGVRIARQAAGKDFFVLGTVGALRGLKQCELSLDEI
IQETLEQVNCLLETNQIDGLLFETYYDEEEIIAVLKAVRPLTDLPIITNIALHEAGITEN
GKPLVEIFGKLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAIKGLKPVSRKFVTP
MVEEAELIKAVKQSETIVDKVKRQVTVIAEIDPPKTLDIEKFTEGVKALDDAGVSAITLA
DNSLAKTRICNVSIASLLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIQQLNKGKGYSGASIKKETSFTAAAAFNPNVKNLS
RCSRLIDKKIAAGADCFITQPIFNKEIIENLAELTRDYEAPFFIGIMPITSYNNAIFLHN
EVPGIQLSDDFLEKIEAVKDDKNKCQELALQESKALIDSALECFNGIYLITPFMRYDLTV
ELVNYIHQKVEEKKQKIS
>A0A1W9SWN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_130|TrEMBL
MSDLKSGSNLEKVLKAGHFAFTGECGPPKGADVEHLKEKFQYLKGNVDAVNVTDNQTAVV
RMSSLAASKLMIDEGLEPNFQMVTRDRNRLAIMSDILGAYALGIRNMLCLSGDHQTFGNN
PQAKNVHDIDSMQLIALVKKMRDEEKFMNDEDIDVAPKMFIGAACNPFADPYEYRVYRLA
NKIEAGADFIQTQCIFNMDKFRDFMKKAVDMGLHKKCYILAGVTPMKNAGMANFMSKFVP
GMDIPASIIKRLKGVDKKNQAEEGIKFALEQVEEFKEMKGVAGVHMMAIEWEHMVPEIAE
RAKVLPRPVV
>A0A6J0EB71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peromyscus maniculatus bairdii|TrEMBL
MHHRGAKVLPAEHCYPSLGTWASEAGCGRLSVPRSISRNPAMVNEGSSSGSEGSKDSSRC
STPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVD
VTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCQQRQEEITGHLHRARQLGLKN
IMALRGDPVGDHWETEEGGFSCATDLVKHIRNEFGDYFDICVAGYPKGHPEAESFEDDLK
HLKEKVSAGADFIITQLFFEASTFFHFVKACTEIGISCPILPGIFPIQAYSSLRQLVKLS
KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV
LKQLGMWTEDPRRPLPWAVSAHPKRREEYVRPIFWASRPKSYIYRTQDWDEFPNGRWGNS
SSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNQHGHTVTC
LPWNDDPLAAETSLMKEELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAY
LEFFTSPETVEALLQVLKKYELRVNYHIVDVQGKNITNAPELQPNAVTWGIFPGREIIQP
TVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDSCL
WQVVEDTFELLNRHTAKREAQAP
>G8AMD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum baldaniorum|TrEMBL
MTSGIPSVSFEFFPPKTEKMEQSLWQAIQRLAPLSPSFVSVTYGAGGSTRERTHNTVTRI
QKETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPETEGGVGGRYVPHPG
GYAYAADLVAGMKKVADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQFFFD
NDAYFRFLDRCAAAGITVPIVPGILPITNFARAVEFAGKCGAAMPQRFAETFEGLDSDPE
TRQLVAATMAAEQCQALQAQGIKDFHFYTLNRSDLTVAICRMLGVKAKQPAVS
>A0A1S8CAQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter sp. VKM Ac-2676|TrEMBL
MNRSLPRNPDTRAALRRTFETLGYEVIPFKKTGDDVQAHVPTDVRLTVTASPAKGIGATV
ELAVRLTKAGYTVAPHFSAQQIADRAQLADIIAEVREAGITEVFVVGGDPTDTPTEFRDA
HALLLAMKELDHPFTDVGIGGHPEGHPTVSDDVLYGALADKAPFANHITTQICFDTKRIV
GWAKELQRRGIDLPLHIGIPGAVTRQKLLRVSNGLGIGESAKFLKKQQNLLWRFFVPGGY
SPDGIIRGLTPSIEASDQRIEKFHVFTFNDLEPTEAWRQQMLNRLAEQ
>A0A2L0WB82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. NXC24|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERASIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFRDYMKKVRDLGLDEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIVGVSGIH
VMAYRQEEYVAEMVHESGVLKGRQPWKHEASRTDDLVAERLEHIRGGMEENQQQMAEAAA
HHPPHQTH
>A0A2L0WBW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. NXC24|TrEMBL
MPSKTENGQRGIRISFEFFPPKSDEAETQLWNTVADLAEWDADFVSVTYGAGGSTKAPTL
SAVRRMIHETPFSTASHLTCVGATREETHRVIDDLLAAGTRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVLALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGANRALTQF
FFDNDAFERYHDRVRAAGIKIPVVPGIMPIQNLTQLKRFAGACGTNIPSWLDERFDGLDE
QADKRANVAADVAAEQIEDLVRRGIHEFHLYTMNRSPLVSAVLERLGIQRRADARAGAAA
>R5U058|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:702|TrEMBL
MKVINLIKSSEKTAFSFEILPPLKGTGIEKVYETIDLLREFDPKYINITTHRSEYVYTEL
GNGLFERKRVRRRPGTVAVAAAIQNKYGIPVVPHVLCSGFTREDIEYMLLDLQFLGITDL
LVLRGDKAKHQSVFTPEPGGYSHAIELENQINDFNRGIFIDGSPIKEPVHPFGYGVACYP
EKHEEAPNMEQDIYWLKQKIESGAQYAVTQLFYDNAKYFAFVDRLRAEGINVPIIPGIKP
FGKLSQLSVIPKTFKVDLPQTLVAEAMKCHTDAEAAELGVEWCINQCRELMRHGVPSIHF
YTVGAAQSVSRVAKAIY
>S9SB56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum fulvum MGU-K5|TrEMBL
MNPVSSVELPIANAAHRPVSVSFEFFPPKTDKMLDSLWEAVQRLEPLSPEFVSVTYGAGG
GTRDRTHEIVSRIAHETSLKPAAHLTCVGHSRGEVDDIARRYWDEGIRHIVALRGDMPDG
QPYQPHPQGYAYAVDMVAGLKRIADFEISVAAYPETHPDAPSADFDIENLKRKIDAGATR
AISQYFFDPAVFLRFRDRCAAAGITVPVAPGILPVTNFAQVQRFSAACGAGVPDWLADLF
AGLDDDPETRRLVAATVAAQQCRILSAAGVDLFHFYTLNRADLVYAICHVLGARPKTA
>A0A1G7JRS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga filiformis|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYEHLDPLMEFKPAFINVTYHRSEHMFKKR
ADGTFEKVEIRKRPGTVAICAALMNHYNVDAVPHLICGGFSREETENALIDLNFLGVDNV
LVLRGDAPKNETFFEPEPHGHRYADELLQQVMHMNNGIYLEEDLQGGVKTKFCIGVAGYP
EKHFEAPNMQTDMSYLKRKVENGADYIVTQMFFDNQKFFDFVNKCREMGITVPIIPGLKP
ITTRKQLNVLPRTFHVDIPADLANEILKCKTDKEVEAVGTEWLIQQSKELKAFGVPVLHY
YTLGKPNVIRKAVEAVV
>A0A1E7RKU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. BIIR7|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAAKLASYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASELIAFI
RAEHGDAFHIEVGAYPETHPQSDDALRDLKYFKAKIDAGADAAITQYFYNADAYFHFVDA
VRKLGVQVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAESVRAFGAEVV
AQLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLGR
>A0A2T1HZP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alsobacter soli|TrEMBL
MAPHPDDIGPEPHAPLPPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPEEVYERAHI
FEGWVDGINATDGSGAHCHMSSVAICALLTRIGYSPIMQISCRDYNRIAIQGNVLGAAAL
GVCNVLCLTGDGVQCGDHPEAKPVFDLDSTSLLSVIRTMREEKRFLSGRKLTSGPDLFLG
AAENPFAPPYEFRPIRLAKKIAAGAQFCQTQYCFDVPLLERFMQRVRDDGLEQECFILVG
VGPLASARTAKWMRANVAGVHIPDAVIARLEGAQNQKAEGKKICIELIQQIREIKGVSGV
HVMAYRQEEYVSEIVHESGVLRGRTPWRRDFQHRLQAVESLGA
>A0A2D7XSS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ponticaulis sp|TrEMBL
MSLQNTPKNIEVSFEFFPPKSEKAEEALWDSVRRLEPVHPKFVSVTYGAGGSTRDRTHRT
VKRMVDETDLTPAAHLTCVGASKAEVMGVVDDYLDAGVGHIVALRGDAPEGMGAKFTPHP
EGFTGSVELIEAIRAHKPEFGKKFEISVAAYPEPHPDSQGLEKDLELLKAKQDAGADRAI
TQFFFEPEPYLKFLDAARDYGINMPIVPGVMLQPNFKGLKRISGLCGASVPNWLHELYEG
LDDDAQQRELITANVAADLTMKLADQGVKDFHFYTLNKADLALATCRLLGLRPASQAA
>A0A0Q4HGQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf22|TrEMBL
MTPTISDLEEARRALDAPLFADLAGDCAVSFEFFPPKSDKMEAALWETVRALEPLAPKFV
SVTYGAGGSTRERTHATVARIARETSMPAAAHLTCVEASRAEIDQVAEEYWQAGVRHIVA
LRGDPPTMGQKFVPHADGYANAANLVAGLQKLHPFEISVAAYPECHPDSEHQQADLDNLK
RKIDAGATRAITQFFFTPEAFFRFRDAAAAAGISAEIVPGILPVSNVGQVRKFAGLCGAS
IPAWMDRLFEGLDDHPGARQLVAATVAAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPRATPVAAAA
>A0A1J5D908|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG2_30_63_29|TrEMBL
MNSEPNLTAVTRRDPSQRLGFHEALETGEFVVTAELMPPKGPDVESFKEKIDVLSGRVNA
INVTDCSRAVLRMSSMAASVIIQQRGVDAVYQLTCRDRNILALQSDLLGAAALNVRSVLA
LTGDGIRHGDHPDAKPVFEVESIGLLDIIRKLNRGKNSAGGTLNAPARILAGAVVNPNFL
PGRSHRKRFLKKVEAGARFFQTQMLTNMEAFESFMEYARPLGATVLGGILVIKSLKNAQF
LNEMVPGIRIEEEILKRFEANDSLDTGLDIAAEQVARCRELCGGVHIMSLGKEQLVLDVL
DRAGL
>A0A8H4RJN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cudoniella acicularis|TrEMBL
MAHAVKLGALTDELVTLLTLISAKNEPSRFSTHKELALRALRYSNYPRTNQFDVANNLDG
LEEKFRVYNEDPLADALRERRNKLEELEVKWTPEILHLLLELSDKPLSNSKLEDLDFLKE
PEPDTGPPLRWKDLVAEDPLLRDKHVWRNVDFAADSSDEDGFEDSLSEHSEFTASTTQSS
VQEEANRRPEDYIVDVPSKERLIQLRDAQFWLKTPSVNGVVLETVKKLLTELQAVREILF
MLAGLPTSLFQQSTEDSKVVEPSKGFALKHASPGAFLQVIKDIADTGSALIVLRSWTNIR
QPIPLLQIFQGAIQNRLTTFDEFLSMIQERFVQPKENTVVSLLSISAEINCHARPLVKLS
TIIQKLVQEPYAHAFRYLEMLFDEACVSQMGGDAELYNFIGTIFFECFQVYLRPIRIWME
EGELIKGDNVFFISETSGAIEPAAIWQSRFKLRQTQDGVLHAPKFLRTAANKIFTTGKSI
VVLKQLNQFSSMQKFGSSIEPRLNFDTVCNLATLQLAPFAELFEMGFDSWIQSKHSHAST
TLRRILFGSCGLQTSLEALSDIYFMANGAIAAWFTNHLFDKLDTLDPSWCDSFTVTELSK
GAFGALSSVNPDRLRTVILPLRSKNKDLNRLRRTVKVLEIVSLKYNLPWPIQIILPATSL
ASYQRIFTFLFQIRRSIHILSRQRLITDVLNTTASSSERALFYALRTRLIWFLQTIYYYL
TSLVLEPGTNKMREALKAAADVDSMIEVHALYIKSAVEKCLLGAKLELIHKTILKILDIA
IKLEDTQAANAVASKEAMDRQQEMMDLSMASLGLHTPQKSRSRPRPNFRRSIAAAINDNS
SSDEEKEVDIDLSILSSNLDEGEQEELYVDKLRKMKADFDRLVRFVGSGLKGVARAGGGD
EARAWDTLGEMIESGFGGSVMGIGGVGRSWQYSCIKRKSYIMTDFDYVSKAEATEVKGPR
PPLDFSYHFSRVTKNREESSVKKFYKYFQIPGIANLAGGLPNASYFPYDTLEAQIAQPER
FKPTPNEPNDPSELAQRLSGASLNKHNDVTASAHLTVPHASTVTNLMKKIDLTTALQYGT
AQGYPPLYSFLRQFTRENLHPNVPYLDGPEIILTNGNTDGLAKAIDALSNIWSEERDWIR
EREGILCEEFAYMNAIQTARPRGLQVVPVKIDFEGMMPYGPGGLEDVLSNWDERKGKRPH
LMYTVTIGQNPTSGTLSIQRRKDLYALCSKYDVMIIEDDPYWYLQFPSATGKEAEARGLQ
LPPVPAPHTFEKSSGYSFLDSLVPSYLNFDYDGRVIRLDTFSKMVAPGCRLGWITAQPAI
VERILRITEASTQQPSGFVQSVIAGLLMGPQPAAVEFSKKSKHEQLTFSGWQTDGWVRWL
AGLRGSYEHRMNKMCENLEEGRFQLKQGTPVKSTDSDWAVISKTKIYSFDWPRAGMFVWV
HIHYDTHPFPTPEILEEKGWQYTRLCFAAVSEEEVDKSSKRFADGVKAFWLVKNKDELDD
GTDTTMSEEHPHLFCSFHTFNMEKITDKIAALPPGSSYFSLEFFPPKTAMGSSNLRARLD
RMSRALRPLFVTVTWGAGGSTATKSLELAELCQRELGLTTCLHLTCTNMSKALVDKALED
AKALGIRNILALRGDPPRSEEYRDSDQKGGEAEEEFEWAIDLVRYIRKQYSDYFCIGVAA
YPEGHADESDPAGQSLEHDLPYLVEKTKAGADFIMTQLFFDVEAYDGFEKRLREHESGTF
KTIPIIPGMMPIQSYQMIKRTTKLSHARLPPDMMSRLDTVKGDDEMVKKVGVDIVSEIVT
HIKKQPCPGPRGFHFYTLNLEKAVSFILERTDLIPNSPFDAEVAILDAPLQTLSVNGSYS
RLSRRQSSVGSDPHNRVIITAPQTSYPDFEATAAEAGIIAEPVNTRANTLAISEGEGSLG
REATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSFNQAIKLWGHPKSIPDITSIFLRHIE
GAIPAIPWSEEGLNEETNTIKSQLLSLNQKGWWTVASQPAVNGVRSSDPIFGWGPKNGFC
FQKAFVELFVPSSDWKALHEKLLSTEVTPQVSFYASNAKGDFISSDYWNKINGAVSEETN
TNAVTWGAFPGKEIITPTIIEEVSFRAWAEEAFGIWVWKDGDLEMEVKLRVAKLNGVLFR
GPDNALQPNYKHLPVGYHGRASSIVVSGTPIIRPNGQIILDPTANPKIPTFGPSRRFDIE
LELGCFLCTSNAMGSPIHIGKEAEEAIFGFVLMNDWSARDIQNWEYVPLGPFNGKNFGTS
ISPWIVLPSALEPFRAEKIKNETELLPYLKEGREDTVYNISLAVDLTTPEGDTTTISNVS
AANLLWSFPQMIAHHSIGGCPMNVGDLLGSGTISGEAGNDLGSLLEMSQAGKKEIMLKGM
EVRKFLKDGDTITVRGVCGKEGELVGFGECTGRVESAVNISF
>A0A0T7ZQA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNSISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLITQLFFDNERSYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A820SJ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MASYEEDLRYLKEKVDYGADFIITRLFFQPATFIKFESDCRSIGIQCRIIPGIFPIQAYA
SLKNIVRLAKLDVPEEILACIEPIKYNGEAIRNFGVQKCVDLCRTLLDSGKIHGLHFYTL
NREYATIEILRKLDRCVRPKSYFHRTSNCEEFPNGRWGLSFAPSFGALTDYHLFYIKIDA
TRDALLDEWGHELADKQDVRRMFACYIADEKNGRVKIVHHFPWKDE
>A0A4J1S9T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNH
>A0A515BKB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter tandoii|TrEMBL
MPLHPDSSSFQPFSIFLEFLPTKHVQPVPSQIAGYPVMMTLADRVRTDNDPEPLVIAQNY
AAEIPKILHFSGKGRDIKDFDCFIQAAQNQGYSNVLLLTGDKLKQHQNGQGNTPRTRYLE
SVNAVMQSKKLAPEIKVGVALNPFKYAHSELAAQYYKLDKKVHAGADYVITQLGFDLEAL
KQAKQYLDDYHTGVDLYACVMPLTLARAEFMDKYKVAGIVLTPHLLELLKQEQESNLTVT
EQNVYARCALQILICRHWGYAGVHLSACHKVEEQRKLEGALERFKNFSLEQCLHEWKILN
CLISGDELKPKVEVFKKSVSSEQVLKFKTMQLMHDSMFDSRIARNVGRKFFNAKLWSGHF
ANQLLIKSEYFSKHGVVGCESCGQCRLADTLYICPETCPKGLANGPCGGTTLDRCEFGDR
ECIHSVKARLAEQMHQTDILKDRLIDTVPIESRGTSSWVNWFKPK
>A0A821BHZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MASYEEDLRYLKEKVDYGADFIITRLFFQPATFIKFESDCRSIGIQCRIIPGIFPIQAYA
SLKNIVRLAKLDVPEEILACIEPIKYNGEAIRNFGVQKCVDLCRTLLDSGKIHGLHFYTL
NREYATIEILRKLDRCVRPKSYVHRTSNCEEFPNGRWGLSFAPSFGVLTDYHLFYIKIDA
TRDALLDEWGHELADKQDVRRMFACYIADEKNGRVKIVHHFPWKDEDISPETNFIHDHLI
KYNRKGILTISSQPAVNGKSSTDSIFGRGIKKWLCLSKKFFTSEKKIPALRTVLKKFPGV
NYHFVNKSGEVNETSTEGEQPIALIWGVFAENMSRTTFLNVDDTKAGMEDLDKEKINKLI
QDASKNSKFFKQQQRREEDNRRRIEVKLSKIKSFTPFQIEQAEKSVDRYLAQLDKTRDLS
RTFCHIDMDAFYAAVEMRDNPALQHVPMAVGGESMLSTSNYLARQFGVRAAMPGFIARHL
CPNLVIVRCDFEKYRADSVKVIEYDENYGSCGLDEAFADLTNHLQIRTNFSEQQRTFPKE
ENSTETITFGMTAEEVVQEMRHRIHLATRLTASAGIACNMRLAKLCSDINKPNGQYQLES
NVEVILNFIRNMPIRKIKGIGKVTALHLESLEIQTVNDIYLKRGILKLIEYPTTFDFLMR
VSNGCGSTTIEHDDLQKSVGHETTFNSVRDSSQLISLCRDLAKKTVDELISHCLLCKRVT
LKIKTVNFENLTRSKTLSSYTDSLNVIADKAVALLKHELDQDIELPALRLMGVRVADLKM
KSSDLPILQFFSKKSTTTINENVHDVIEDIDNVDEDEEEEREKDENENEEFLSMENSHLG
GCDSKLTHQDDEDSNSSTTACPVCQKLLLGDNEKINKHIDLCLNGEMVRTTIKEENRRTS
PQTKMNKRIQLTQSKSTPPKKRQKRKSDATPQRAHGIDNYFFKTESK
>A0A7S8DQ28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium pseudograminearum|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WEAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPSADRP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKAIQDIAQLFVSYLNNKIESLPWSESPLTTEADEIRDDLIE
LNKRGLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPV
ANGAVDTEPIANGTAATAVAN
>A0A087MB98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurospirillum sp. SCADC|TrEMBL
MIENFIEKLKHDTFLTLETTPMHEPTFEPIIEKIAALGLDKIVDGFSTTDNPLARLKFNA
LFGALKLQTQFHKPVIATMSMRDRNKVALQSDLLGANGFDLRTILALTGDPASASDQPAV
KGVFEGNSTLLLEIIQCFNAGIDYSGKPFKTQPKPIYSFTVCNAHANTPKNLMKKMATKI
KHGAVGIITQPVYSVENAKMLLNLLKDAKAEINKEQSQAQLILGFFPIIKLRTAQFLSAH
VPGIHVPSVWMDKLSHAKKISEEEEKKVGFELSLNAFLELKKIHPKIHMMSANNFELVAD
LVKY
>A0A495S2Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. AG790|TrEMBL
MTAPLRLREATRRCPKRMVHGPCGGVAIDGGCEVPGIRCSFVDDPAVLHDLEFSAAEVDA
PNAARASGDALAVRPRGEASTAFAALVEAGAVITADLPVRSTDPAVITEAGVRLRELTAV
IAGEPPGLRDALSPTHKALLLAAAGSRVVAGLTCRDRNRVAIEGELAALADLGVSGVLAV
TGDHPASTALPQAQPVFDLDATRLTALARRAGLFVAVAEQPSAPPVDYRPTRLARKAQAG
AGLGILNLCGDLDEIRRFTAALAATAAPVPVLVSVPVLTSVATARRLAALPGVGLPDELV
RAVAGADDPVDAGIAAAVSWARRALAIPGVVGIHLSAITAAASAPTVRAADAAELAAVDA
LASAAARLRTAISADTITAETAGTA
>A0A0Z8FU64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VHNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARTIHQATHSLFKHYS
>A0A2S6WWC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MH60|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPGADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PPELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A4U2LCR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puteibacter caeruleilacunae|TrEMBL
MLKDRLAKKESGFLFYGLTPPKKNTDNEKIKVIAEKQIARINSVDIDGLVLYDIQDESSR
TDRERPFPFMPTLAPDYYSENYLSELEVPKIIYKSVGKYSPSEFKGWIEKSDDANCSVFV
GSPSKSQVSNLSLSDAYKINHDADSSMLIGGVTIPERHIKKGNEHIRLLEKIDSGCSFFI
SQCVYSINNTKDFLSDYYYLSQEKNVDLVPIIFTLTPCGSLKTLEFMKWLGIDIPKWLNN
DLKNAKDILSDSIHVCKAIAAEIIEYSRAKGIPIGFNIESVAIRKEEIEASIELLKDIKE
MMSK
>A0A1X6WU75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium yomogidense|TrEMBL
MTGDTSTIARLLRTARLEVLPTDSITAEVRAHAPQHRTVTITASESLGLDATLAVACALR
ADGRRVAPHLAARMVSGRSHLEDIVDRLHAAGVDAVFVPGGDATPGPGAYTSSLALLRDL
EQMDHPFRDIGVAAYPESHPTIPDAEVVRALADKHPFATEMVSNLCFDPDALSAWIRSAR
DRGTALPLWLGVPGRVDAARLARVGARIGVGQSLRFLKGKLGTITRLVTPGGVDTHRLLT
RMSGTLDDPTSRIAGLHLYTFNQVELTEAWLHDTGG
>A0A098LDJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporocytophaga myxococcoides|TrEMBL
MKVVEHLKNAKKTLFSFEILPPLKGQDIQSLFDGIDPLMEFKPPFIDVTYHREEFVFKKR
ENGLLEKKSIRKRPGTVGICAAIMNKYRVDAVPHIICGGFSREETENALIDLNFLGIDNV
LALRGDAIKSEGTFIPEADGHHYASDLIKQIKCMNQGVYLDDDLQNPVPSDFCIGIAGYP
EKHFEAPNLQTDIKYLKQKVDLGADYIVTQMFFDNQKFFDFVKKCREEGITIPIIPGLKP
ITTQKQITILPSIFHMDIPVELSEAISKCKTADQVKEVGIEWTIQQSKELMEFGVPVLHY
YSMGKSDSVKQIASALF
>F5P122|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella flexneri K-227|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCISAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A420IE02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Golovinomyces cichoracearum|TrEMBL
MTMEKITDKIAALPPGSNFFSLEFFPPKTNMGLSNLRSRLDRMARALRPLFVTVTWGAGG
STSTNSLELADLCQRQLGLTTCLHLTCTNSSQELIHKTLEAARVLGIRNILALRGDPPRK
DTEIVNSEIESPAEFEWAIDLVRYIKKNYGDFFCIGVAAYPEGHADGSDPDGQSLESDLP
YLIEKVKAGADFIMTQLFFDTGAYDTFEKRLLEHESGCFKNLPIIPGLMPIQSFQMIMRT
LKLTHVKMPSDVIAYLTSIKGDDELVKKAGVEIVSKIVSHIQDSPAPPIGRRGFHFYTLN
LEKAVSFILEKTSLIRLSHSASVNDNSISNFTNIESSAFPTNPNINNHTDHLGHQQSLII
SDSSNTVSNTSPLTSQPQVEVKLSETNSFSNCIENRASTLAISKGGDPLGREAIWDDFPN
GRWGDARSPAYGELDGYGINIHLYLNQAIRLWGYPQSTNDITSIFTNYIKGSLGAIPWSD
EPICRETDVIKDQLLKLNEKGWWTIASQPVINGIKSNDDVFGWGPRNGFVFQKAFVELFL
SSEDLLQLQAKVKKMEMANKISWYACNSKGEFSSSDTLAKSSSNNRGSINAVTWGVFPGK
EIVTPTIIEEISFRAWAEEAFKIWAEWGKAYTGSSPTSPDFQKAQASHQLINRLREEVWL
VNIIHHGLIEKDGLWDLLIG
>A0A520LAH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella sp|TrEMBL
MKVTEHIKNANGNTQFSFEILPPLKGEHIQSIFDNIDPLMEFNPPFIDVTYHREEYTFKD
VGNGLLKKQIVKKRPGTVGICAAIQNKYSVDAIPHILCGGFTKEDTENFLIDLDFLGINN
VVALRGDAVKNETYFKPEKEGHAYASELVSQISDLNNGIYLDDELENCSETNFCIGVGAY
PEKHTEAPSLDSDIHFLKKKIKKGAEYIVTQMFFDNQKYFDFVKKCRNAGIEVPIIPGLK
PIATKKQLNLIPHRFHVDLPQDLILEIIKCDDNSQVRQVGIEWCIAQSKELQKAGIPVLH
YYSMGKSSNVKKVAEAVF
>A0A1G7VVU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella thalassocola|TrEMBL
MKVTDHIKNANGKTLFSFEIIPPKKGNSIQQLYNNIEPLMEFKPPFIDVTTSREEYLYIE
KDGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGINNV
MALRGDAMKHQQYFEACDGGHQFAKGLVSQIQNLNKGHYLHDVLEADDKSDFCIGVAGYP
EKHIEAPSLRTDLKRLKEKVDAGADYVVTQMFFDNKKYFDFVKAAKAEGINVPIIPGIKP
IAVKRHLQLLPQVFKIDLPEDLIEAVDRCKSNEQVRQVGVEWAISQSKELQQAGVPVLHY
YSMGKSDNVKAIASELF
>X6PVD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. ICM33|TrEMBL
MGNNITDIKQLLNDETDEKHFSFEVLPPLKGNGTASLFRNIDQLKEFNPSFINITTHHSE
FVYHEREDGLLERQRIRRRPGTVAIAAAIQQRYGIPVIPHVICSGATKEDIEYELLDLQF
LGIENLMLLRGDKAREDRFFTPTEGGHSHTTELIEQVNSFNEGIFIDGSTMKHPGRRFAY
GVACYPEKHEEAPNLEQDLRYLKMKQDFGATFAVTQLFYDNEKFYNFVDQARKIGVTIPI
IPGIKPFAKLSQLNVVPKTFHCDIPEELAGLALLCKSDEEARLLGIEWAVRQVKDLYAHG
FNNVHFYTVSAVSSVHEVMKRLVEIGLLQQNSK
>A0A220SDY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. T16E-39|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYRNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLVERKITRMRPGTLGICSAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIEN
IMALRGDAMKGHQYFEATPGGHESAMDLVYQINDLGRGKYLHDEDQISDELNKFCIGVAG
YPEKHIEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGI
KPIATKRHLKLLPQVFKIDLPEDLINEVESARNNEAVKQIGVEWAINQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A2S4VY80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia striiformis|TrEMBL
MKISQKLAAAESENRISWSFEYFPPKTDNGLTNLYDRIYRMSQLGPIFIDITWGAGGSTS
NLTTEFVKTAHEQFGLETCMHLTCTNMPKEKIDTALKEAYEFGCENILALRGDPPKGSTE
WTATEGGFEHAIDLVRHIRAGYGDHFDIAVAGFPEGHMHSSLTKEQETIYLKEKIDAGAN
FIFTQMFYDVDIFIDWVREIRAAGITVPVIPGLMPIQSWAQFKRVTNFSKTIVPQYFLDT
LEPIQSDDQAVREAGTKLVADMCRKILNSDLGIRILHFYTMNLERGTKMLLDELNLNPSR
DITNPLPWKMSLLGKRRSESIRPIFWANRAKSYLSRTETWDEFPNGRWGDSRSPAYGELD
GYGININSATIETLKGLKKFPTSLEDLARIFANYCGARFPGEEPVKYLPWSDIALSEETG
KIEDVCQPAVDGAKSSDPVHGWGPRGGYVYQKAYLEFFCCPEKFQSLTERLEQDPEVTYY
AVTKTGDLVTNNTRPGPNAVTWGVFPGKEIVQPTIVELVSFIAWKDEAFELGHQWAELYK
DTAPESSKFIHEIMDSWYLVNIVNNDFRKSNDDSENSALFQFFGPEPVIVKEDGVPSTNG
FHHSNGISKVNGTALLSMDSTGTSKPCHLSCKSDV
>A0A837IIJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Collierbacteria bacterium GW2011_GWB2_45_17|TrEMBL
MLEKSAERLTPPEYLKQWITEANYEVLPTEKALDLINIIPETNTISVTCRPTGIEETVHF
AEMLGPEKMKRVWPHLAARRIYSQDHFDEVSLRLINAGMEKAFIVGGDGDPSFEDFKKTE
DVLNGLLIRGILPKKIRIGGYPEGNPVMDMDPIEVLLQKQEFAEKAGVQMEIVTQMFFDA
DTLFNWLMEIRQRGVYLPVELGLLGKLKWNSFVKVLETIGIKDAMAFLKSKPKLAMSLAT
GMITGFSPRYLLTELAEKNTPELGINGISIFTLGNITNSVKCLTDIASENI
>A0A5Y9DGE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGSNCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEIFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKAKIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A7W4B011|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. SG44-6|TrEMBL
MAFHHAQHAQSLNQSLSELNDINVSFEFFPPSTPEMEEILWNSVRRLEPLNPKFVSVTYG
ANSGVRDRTHSVIERIQKETNLLAAPHLTLVDASDEELVELAKHYWNSGIRDIVALRGDL
PEGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDARNAQADLINLKKKIDAGANRAI
TQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVTNFKQTKRFAGMTNVAIPHWLHRQFEG
LDDDPATRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A3T2GSC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMRKAEEQGHANEEGMAIARELVDAICEHFQGVYIITPFLRYDLSI
ELAKYVQNKQQVQIGSK
>F9XCC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymoseptoria tritici (strain CBS 115943 / IPO323)|TrEMBL
MHITKKLAAAHEKGDATYSFEYFPPKTAQGVQNLYDRMDMMHGFGPAFIDITWGAGGRHS
SLTCEMVKVAQSAYGLETCMHLTCTDMELSKVDDALKEAYNAGCTNILALRGDPPREQEK
WVETQGGFRYARDLIKYIKKKYGDHFDIGIAGYPEGPDETTTADEHIVYLKEKVDAGGTF
VVAQMCYDAELFIEWVQKCRDAGIPESVPIIPGIMPISTHAAFIRRANWTQARIPPAWHE
ALEPIKNDDSAVREVGRDLIVEFCQKLMAAGIMHLHFYTMNLAAAVRMVLEKLDLTPSAE
SPHPDIKPLPWRQSLGLNRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
SLDEYGIGLKGTNEHNRKLWGEPQTIDDISKLFVKYMSGKVETLPWSEAPINDEANVLVK
DLIELNNRGLLTINSQPAVDGVKSSHPTYGWGPRNGYVYQKQYLEVLVAPELIDTVIQRM
ENDEDITYYAVNHSGELKTNVTADGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYY
LGLEWSKCYEEGSKSRALITELTKSWYLVNIVHNDFRNQGGIFPIFDGLQVPGVNVEKLA
NGITNGHAENGKTTEENGKPETNGVPDGNNVVNGADKKA
>A0A160PF83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum populi|TrEMBL
MPSASRHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVNATREEIDAVVQSYWDAGVRHIVALRGDPAEGVG
HTYRPHPGGYAQTCDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFDNEIYLRYLDKVRAAGIDIPIIPGILPVQNFKQAASFARRTGASVPYWLAARF
EGLDNDIETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
VAAAKAA
>T0GRZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira noguchii serovar Panama str. CZ214|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDLKLMETMKELSLLDPDFVTVTYGAGGSTRDK
TVQILSQISKNYSIPTVSHFTCVGANKDQILETLKGIRSSGIVNLMALRGDPPKGEGEFK
KVENGFGNATELISFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVKNLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCKELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A191UWK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces parvulus|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPAADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVRHFVD
KCRAGADYAITQMFFQADSYLRLRDRVDTAGCETPVIPEVMPVTSVKMLERLPKLSNAAF
PPELKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A3D5W3T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micrococcales bacterium|TrEMBL
MAQREATMTTSELYRAPRPTISFELYPPRTPRGEEQVHETAARLAAGEADYFSVTYGASG
TTSERSQALVEHLLAETRVPVIAHLTCVGRSRSQLRDVVSGLLDAGVRDFLALRGDPPEG
GEWSPGGDGLARACDLVALIREVEAERFGLPPASPVERLVARRTRRDGVSIAVAAYPGYT
VPGLSGEFQVRDDELTALRAKQDAGADFAITQVFFDVEAYVALQRAARAAGIVLPLVPGV
LPLTDPDRIRRLCALNRIPEPAELLAELEAAGGPEEAYALGVRRTADLVRGVLAAGAPGL
HLYTFNQHAAVTRLLDEVLAPA
>A0A1G0EFZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium RIFCSPLOWO2_12_FULL_59_22|TrEMBL
MNKPLFSFEFYPPHTPEGVEKLAATRLQLAALHPDFFSVTFGAGGSTQERSLEIVQQIKA
ENLEVAPHLSCVGSTRENIRAILQTYKQLGIKRIVALRGDLPSGMASTGEFQYANELVSF
IRAQTGEHFHIEVAAYPEFHPQARSARDDILNFKRKAAAGANSAITQYFYNADGYFHFVD
ECRRLGVTIPIVPGIMPIGRFSQLARFSDTCGAEIPRWLRKTLEGFGDDSESVQAFGLDV
VTELCEKLLAGGAPGLHFYTLNQAAPSLEIWKRLGL
>A0A1I6DI13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poseidonocella sedimentorum|TrEMBL
MTVPAVSFEFFPPKDLAGSFRLWDTVQVLAPLGPRFVSVTYGAGGTTRDLTRDAVATLHS
QSGLNVAAHLTCVNATREETLEIARGYAAAGVSEIVALRGDPPKGAGGFTAHPDGFADTC
ELITALKDAGDFRVRVGAYPEKHPEAADEQADIDWLKRKIDAGADEAITQFFFSAETFLR
FRDRAAAAGITAPIIPGILPIENWAGTKRFSASCGATIPAWLDSAFETAKRDGREDLLAT
TVCTTLCTRLVDEGVEALHFYTMNRPELTRDVCHALGVTPKVQLENVA
>A0A2E6ZHZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia sp|TrEMBL
MIDKVTPSVSFEFFPPNNIKMESTLWKTVKRLETLEPKFVSITYGADGSSQERTHSIVSK
IINETQLTPAPHLTCINATRDEIDEIALTYWDMGIRHLVALRGDAPKGSKSYTKNPKGYA
FASDLVTGLTKIANFDIYVAAYPEVHPEAKDALFDLDNLKRKLDAGATKAITQFFFDSDQ
YLRFRDRCGQAGIDSKIIPGILPIIRFEQMERFAKICGTKIPKKLRDQFENSDRDQENQR
LISTSTAIEQVKYLESQGIEDFHFYTLNRSEIPFAACQALGIRKNSKKIGNA
>A0A7W0HJ48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosalsimonas propionicica|TrEMBL
MNFKKKLSAAEFVVLAEMNTPKGVDISELVTNARRVKDRVDAVVVPDMDNGVMRMSALAG
GALLRREGLETIVHVYGRDKNRMALQGDLLAAYVLGIPHLLVVPAEPMSNGDHREAVTVD
DLDESGILQMIRSLREGVDLSGFDLKGTPDFTSGCAMAQVAEDSGLDQEIETVKRKVEAG
AQYIVTPPVFDLDAYGRIAEALKPLGVPVIATVFLLKNVGMARYMSIHDPGSRISEDMIR
RIRKAPDREAECIRMAGETAAELKKMVQGIKIATLGWEHRLPDILASAGL
>A0A7X8U2B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MRTSEIFKNKTVLSLEVFPPRRTASIDTIYNTLDQLQGLNPDFISVTYGAGGSATNTATL
EIASAIKNHYGVESVAHLPGIHLSKDEVLNMLAAFKEAGVENILALRGDVNPDLVPKQDF
RYASDLVSFIKANGDFNIIGACYPEGHNECPSLVDDIHNLKIKVDAGTDQLITQLFFDNS
YFYSFRERACIAGINVPIEAGIMPVVNKKQIERMVSLCGVKLPEKFVTMMERYENNPVAM
RDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYIAHKIYEAVSTLLAA
>A0A7X6J7U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. SG570|TrEMBL
MAHIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEEVYERAAIF
SGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPHDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLNEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDAIIKRIEGAQDQKKEGKQLCIDIINEVKEIKGVSGIH
VMAYRQEEYVAEMVHESGVLKGRQPWKHEANQTDALIAERLEHIRGGKEENQQEMAEAAA
HHPPHKTH
>A0A7Y3CQ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MTTETLPKPSVSFEFFPPNTAAMEATLWNSIERLADLGPSFVSVTYGADGSTRERTHSAV
ERIIRDTELTPAPHLTCIGASRGEIDDIAREYWDMGIRHLVALRGDAPKGTDTYTPTAGG
YAYATDLVAGLRNVADFDVSVAAYPEVHPEAPSADFDLENLKRKLDAGASRAITQFFFDA
DVFLRFRDRCAKTGIDSLIVPGILPITRFPQLERFADMCGASIPDWLRDRFDGLDDDEAT
RQMIAASVAIEQVRALQKEGIEDFHFYTLNRSELTYAICHALGVRPDRAAA
>A0A7K7K2G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agelaius phoeniceus|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRRVLQAGGPLFIDVTWHPAGDPGSDKETSSMIIAYTAVNY
CGLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLV
KHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVYAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVRALLKVLRRYELRVNYH
IVNVKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A1J0VCU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas aestuarii|TrEMBL
MNDLRSVTSPEQGLRGCLALASPRYELLPLADMREAAGLLPAGALVTVTCSPRHGIERTL
EEAEWLSRSGFRAVPHLAARLVRDRAHLEEIVSRMAAAGIDDCLVVGGDAPRATGDFADG
LALLEGLAGHPARPSRLGVPAYPEGHPGFDAAALQRNLEAKARLADYAVTQLCFEALPLR
DWLRLQRDRGLALPIYAGIPGVIAHARLLSVAMRIGLGASTRALGRQRGLLGRLLRPAVY
RPEALMRGLWPALDEPDGFAGLHVYSFNQVGATRAWLEALRATRCAGTDPVATLLSPSGD
SGSGIVKPAARY
>A0A6B3PPU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavihumibacter soli|TrEMBL
MKITDHIANANGKTLFSFELLPPVKGQSIQGIYDAIDPLMEFKPPFIDVTYHREDYIYKQ
HDNGLLEKVSYRKRPGTVAICAAIMNRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARKADASFIPTPGGHTYACDLLQQVSNMNNGLYLHEDHDSSFSTNFCIGVAGY
PEKHFEAPNMKADFKYLKQKVDMGAEFIVTQMFFDNSKYCSFVKRCREEGINVPIIPGLK
PITSSKQLISLAKFFHIDIPEELSDAILKCKSEKEVKDVGIEFMIEQCKELVKFGVPVLH
FYTMSNPGPTKRIAEAIF
>A0A1X9U625|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium damselae subsp. damselae|TrEMBL
MQPITNYQALSLQDSELRVRYNDVTRGVYFIGTTPPKTSTDLSDVDGIADKLVDRIKDLA
FDGLIVYDIQDEGSRISKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSEPEVFN
QWLNEAWEQYQVRDIVLVGSPSTQNQVSLPLHKAYKTIADNEHPFFTGGIMIAERHAKKG
NEHQRLIEKYQQGCNFFISQAIYDTQATIDLLTRYAIECQEKGLKPQRIILTFSPCGSAK
TLEFIEWLGVSVPEATSLRILNADNPLHESIKMCCNSLNQILEAVVEYDLPLGLNIESLT
NRKEEIEGSILLYKLLRSTMDMYLAQHEFRKQQGLKKAF
>A0A2D5K2L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MITESLXASKNXFXFTAETTPSVSTNLNENVEKISNLIGVADAVNITDAPNCKTKLSSLV
VAGEINKSGLDVILQITGRDRNQIALESEILGALSLDINKILCLSGDRPPEDGPMAVNEM
NSSDLINLLKLMSKGNLSDGTEIKEPIDLVSGCADSIHDHFVRDKHSDFFVEKVNMGVSF
VQTQYCYDIDLCKKYSQFIQENNLSASTKFIIGLGPLKSAKQASWMRDNLYGVKIPDSII
NRLDQSTSPLDEGKKICEEIIKELMDLDGISGVHLMGPNCENQCADLIKIFR
>A0A2N2ERH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium HGW-Elusimicrobia-3|TrEMBL
MKVTERLKTGEKVYSFEFYPPKTAEDTAKLFNTALELKALSPDFVSVTNSSSGVMPYRTV
ALCGVLKSQFGLEVVAHLTCLAHTRAEIAEICSGLKKMDIVNVLALRGDPQNVAAGALRR
DYSYASQLTTDLVKDGGFDVGGACYPEKHPESPSPEADIARLKEKADAGAGYLITQLFFD
NDFYFRFLDRAAAAGINLPVLPGLMPLTGYRQMQNFTQMMKVTIPEPLRAGIERWEGDKD
GMFKFSVDYASRQAEGLLKGGAPGLHLYTLNRSRAAMAIFKNLKGAARP
>A0A7S8EJQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. NBSH29|TrEMBL
MTQLSRRSDIGDKIQVSFEFFPPKSDEMEARLWETVTRLEPLSPSFVSVTSGAGGSTRER
TARTVGRILKETSLVPAAHLTCVDASRGTVDQVIGEFAAMGVSRFVALRGDPAEGVGARY
CPHPEGYANGAELCGALREAGEFDVSVSAYPEKHPESPDFATDIDMLKRKVDNGATRAIT
QFFFDNDLYERYVERVRRAGIYIPIVPGVLPVHNFTQVANFSARAGAHIPGWVAERFEGL
AKDPQTHALVAAAVAAEQVMDLVERGVGDFHFYTMNRADLAYAICHMIGIRPSTTQGSIA
GEASAAA
>X1E083|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
SGVSLPDEIVSRMEDAKDPKEEGARICVEIIEQLKEIEGIHGIHIMAVAWENIIPVMVKQ
AKLWPRPKIENIRAS
>X1J8N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
AGIIVLASAGMARYMNNNVPGIIVPQATIDELASTEKDKRLQKGIEIAAGLIKTVKEENL
CHGVHIMAVGNERIVPDILEAAQLTGVRH
>X1KKZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
TDNQTAIVRMSSLAGCVLLKQQGVDPVMQIVCRDRNRIAIQSDVLGAIALGIGNILCLSG
DHQMFGNHPTAKNVFDIDSIQLIQALKNMRDEKKFLCGDDISGEVPLFIGAAANPYADPF
EFRVARLAKKVKAGADFIQTQAVYDVVKFAKWMEMVTDRGLDKEVHILAGVIPIRSAGMA
RYMRDYVSGVSVPDEVIASKVKKHGERR
>X1QUU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKAGTNLEKVLESGRFAVTAEAGPPKGTSAAVMQRKGELLRHCCDAANVTDNQTAIVRMS
SLAGCVLLKQQGVDPVMQIVCRDRNRIAIQSDVLGAIALGIGNILCLSGDHQMFGNHPTA
KNVFDIDSIQLIQTLKSMREEKKFICGDDISGEVPLFIEAVANPYADP
>X1STG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
PEILKIGRKAEAGCEFIQTQVVYDLDRTIEFLTGIRKYKVPILLGIFPMKSYGIAKGFDT
FVPGVSVPKEILAKWKSVKKDVTDKKQKKELYDQYNYELFKPFVSELRKKNLIDGIHCMA
VHYPRIFPKLKDIIGG
>A0A6A5T473|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clathrospora elynae|TrEMBL
MHISQKLAQAREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDDALRDAYNSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDDVDQLIDHLKEKVDAGGTF
IVTQMFYDTDLFLEWVRKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTKCNIPKHWTEAL
EPVKNDDVEVREVGKNLVADMCRRLIDAGILHLHFYTMNLAQATRMVLEELDILPDVGSP
LEKPLPWRPSLALNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPTSIQDLSDLFVRYMEGKLDSLPWSEQAITNEAGSIKHDLID
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEHIAEIITRLERDP
EFTYYAVNKEGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHTEVSPSRYVIQDVVDTWYLLNIVHNDFHATRGIFPIFDGLEVKDMEKQLHNPSVNV
PISNGHEATNGSTAAKEKPTLIDAAKSVAVEVTNGLKGLTISN
>X1PGH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MQVINVLKKADKPVFSLEITPPEKGKSIQGIFDTIDMFKEFKPHFINVTYHQQRVVYTEK
KGIIKKIPKRKNVGTVGICSAIKHKYGIETVPHLICGGFNKYDTEDALIDLNFLGMENLL
VLRGDPRPEEKEFIPEKEGHKYASQLVRQVSDMNQGKYLEELNNGHPTHFCIGVAGYPEK
HWEAPSTEQDLLNLKNKVDQGADYIITQMCFKVNKFKEFVKKARDIGITVPI
>X0ZL80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSKLQESLEQGLFTVTGEIGPPKGVDLEKCLEEASHIRDRVVAINVTDNQSSVMRAGSLA
VCARLVQEGYEPVFQITCRDRNRLAIQSDVLSAYILGIRNILALTGDHTSGGDHPGSKPV
FDLDSVSLLMAITSLINGKDLAGQELDGV
>A0A4Z0PVS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter aquaticus|TrEMBL
MKVTEHLARANGKTLFSFEVLPPRKGENIQTLFSNIEPLLEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGYFKPEPDGHSYACDLIGQMANLNKGEYLDEEQDDTWATDFCIGTAGY
PEKHFESPNYAADLRYLKHKVDRGADYIVTQMFFDNEQYFNFEKRCREAGIHVPIIPGLK
PLTTKGQLTMLPRSFYLNIPEELSEAVHHAPNNDAARQIGIEWCINQSKELMAHGVPCLH
YYSMGKSESIRRVAAALF
>A0A1X4J0L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoruegeria sp. SK021|TrEMBL
MSKPRISFEFFPPQTLDASFRLWETVRALAPLDPGFVSVTYGAGGTTRKLTHEAVATIHK
HYGLNVAAHLTCVNASRDETLEIAQAYSDVGVTEIVALRGDPPKGSDRFVPHPDGFADSC
ELIEALAATGKFKLRVGAYPDPHPEATDTLSDVTWLKRKVDAGAHSAITQFFFEPDTFFR
FRDACVAQGITAPILPGILPIENWTGIRKFAARCGTAIPGWLDDTFDAAAKDGRSEEVAT
ELCVDLCRRLMAEGVEDLHFYTLNKPHLTRNICAALGVTSATPLEHVA
>I3E1S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus methanolicus PB1|TrEMBL
MSIYLGNRLVSSNYFTVTSEMVPPRSWNPSPLVEQAVRARGYVDAVDLSDNLLAIARLSP
VVGAFFIRQVGMEPIVQVNLRDRNRMGIQSDLMGLAALGVKNITILGGYPARIGTEPNAK
EVYDLETMELVRYVRRFVDEGKLFDNTVMEEAPQMTIGVVENIAGKPVKELIDRLEAKID
AGANFVRTQLVFDLDLLGEWMEEARRRGLHERSYIMASILPLRDADHVDAVLKIPGIAIP
ENIIKRIKEADSPAEGMKMVVELIDKLRSINGIRGIHIRPLGGMDRYVSTIVKEAGLMNR
KLEEAAEYAS
>A0A1I6GQU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter gudaonensis|TrEMBL
MQSQTQFKRRFSFEFFPPKTDQGKEKLQNVRSQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRQEIGELLDLYREHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDADSIRK
FGEEVVTNMCEKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A7J8KCV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rousettus aegyptiacus|TrEMBL
MVNEPRGHGSLNPRLEGSSSESSKDSSRCSTPGLDPERHERLKEKMRRRMESGDKWFSLE
FFPPRTAQGAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLE
TILHMTCCRQSREEITGHLHKAKRLGLKNIMALRGDPIGDQWEDVEGGFCHAVDLVKHIR
SEFGDYFDICVAGYPTGHPDTGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKAC
SEIGITCPILPGIFPIQGYHSLRQLVKLSRLEVPQQMKDVIEPIKDNDAAIRNYGIEQAV
SLCQKLLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRLLPWTVSAHPKRREEDVR
PIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREQLLKMWGE
ELASEESVFEVFACYLSGEPNQNGCKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTIN
SQPNVNGLPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYEQRVNYHIVDV
KGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEDES
PSRMIIQYIHDNYFLVNLVDNDFPLDNCLWHVVEDTFELLSRPGSE
>A0A6G3RGS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID339|TrEMBL
MTALRALIDQDTPSFSFEFFPPKSDAGARTLWKAIRRIETLAPTFVSVTYGAGGSSRDRT
VEVTKRIAAETTLRPVAHLTAIGHSVAELRHIIGQYADAGVRDVLAVRGDPPGDPGAPWT
PHPDGFTHAHELVRLVKESGDFSVGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQ
MFFDVEDYLRLRDKVTAAGCTTPIIPEIMPATDVRQISRFAQLSGAAFPEHLAHRLEAAR
HQPAEGHHIGVEHATAMAQRLLAEGAPGLHYITLNRSTATLEIHRNITDARSTPHDLAAH
H
>A0A837R2Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MSHLSPCFQQNQFFVLVEYLTSLHEIYPVRREFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEFFLEQAKSANVQNLLLLTGDKLKEHHNGRDGQLRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
SGKEFSPEITYFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALVAK
VLIKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVAQTEILKEKLIPTVPLETRGTSSWKNWYLAT
>A0A0F6FVL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis subsp. kurstaki|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPNFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A340XVR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lipotes vexillifer|TrEMBL
MDRSKPKVLPAGHCCPSLGTRAWEAGSARFSVPPSISRSSAMVNEPRGHGGPSPRWECSS
SGSESSKDSSRCSTPVLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKRLGLKNILALRGDPIGDQWEEEDGGFSYAVDLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEAGLKHLKEKVAAGADFIITQLFFEADTFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQALSLCQELLASGSVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTGEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLQVNRRGILTINSQPNINGKPSSDPVVGW
GPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGDNITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEAESPSRAIIQHIHDSYFLVN
LVDNEFPLDSCLWQVVEDTFELLNRPPQSKRETEAL
>A0A5J4YRE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyridium purpureum|TrEMBL
MSCLSAVAVASSASSVLANGSPTPVAAVVAKKGASAARIADKIAQCEREGKLFFSFEYFP
PKTDTGVSNLYERVERMAAYEPLFCDMTWGAGGSTSDLTLELVGNIQQFLGLDVMMHLTC
TNMPAGKVVMGLEGAKARGCRNILALRGDPPAGKEWSKCDDGFEHATDLVRFIREKFGDY
FSIGVAGYPEGHPSGYLDGKLTLEQEMAFLKDKVDAGADFIITQMFYDVENFLQWVSSCR
AAGINVPILPGILPIQNYGGFKRMTGFCKTMIPPAVEARMEELKDDEAAVKEYGITLGVE
MCKRMIASKLVLGLHFYTLNLEKSVLSIVERLHLVPMTEAIRALPWRPSTASEKRRGTED
VRPIFWSNRPKSYIKRTSEWDNFPNGRWGVSESPAFGDISHHHLAGSGGVTPELKQAQLQ
MWGEPRSVADVEEVFVRFLEGNIKRLPWTESDVLSPETGTIQGPLKWLNKHGVLTINSQP
RVNGAPSSDKCFGWGDKHGFVYQKAYLEFFASEKIVDALFAHASAFPSLSMYAARADLSA
PIRSNVSDTRSSRANAVTWGVFPDAELVQPTVVDPTAFKAWREEAFDIWTQVWASCTPDS
SPARQVLQQIHDTYYLINIVDNDYVAGDIFRIFTSIFSEL
>A0A271LGA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium temperatum|TrEMBL
MIARQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPLLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRTNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A5D0NXI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura chibensis|TrEMBL
MAFEIVCEVEPPMKPDLTRVRHQIGVLSPVADSFLIPDNHIGRATVSSVAVAHEVQAMGA
RGIACLNSRDRNLLGFRRDLLTAAAYGVDRFLFVYGDKPTAGGRTSELTVRAMMEETRAA
AEDAVFAGCAPFQIGVTTGLRKTAEWKRSADFTFVQVSYSVDELLRWRDGARLTGPVYAG
VMVLASAGMARNLAAAIPDIAIPAELVDAVERDRAAGVAAACEQVLAIRDSGAFDGVHLV
PVSRYREVAARLEREL
>A0A2M6Y978|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG08_land_8_20_14_0_20_45_12|TrEMBL
MISKFRQVLNSGKFVVTSEIGPPKGTNIEKMLHHIDLLKDKVDALNVTDHQSSVMRFPSI
GGCLAIKEQGGEPILQMTCRDRNRLALQAELLLAYTRGIRNVLCLTGDAIPVGDHKEAKG
VFDLDSVQLLRAIRQMEAGKDLGGNELDGTIEFCAGAIVTPEARPIEPQLIKFEKKVEAG
AEFFQTQAVYDLDNFAKFMQYARQFSVKILAGIVLLSSASMAKYMTENVPGIFVPKYLID
ELASAPRGEALNKGKEIAGRMVATLKKESICDGVHIMAIRREEVVPDILAIAGL
>A0A448YVV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudo-nitzschia multistriata|TrEMBL
MSTTDANPKIIDLIKQKEDGSKPFVSIEFFPPRTETGVKNLYARMERMKASINPLFSDVT
WGAGGSTAELTLDIANQLKKTGHVANMHMTCTNMEKDGDPKKAVHSALQTAKDSGIMNIV
ALRGDPAHGQEEWTAADGGFTCALDLVEYIRENFGSEFGISVAGYPEGHPNAISLVEDPS
TMTEAEKARSSTDDEGKVYTCRDEDYKKEMDYLKKKIDAGGDFIITQMFFDTKVFGSFVK
DCRKWGIDCPIVPGLMCINAYAGFVKMTKFCKTRVPTELRAKMDSLKDDSDAIKAFGIEF
GTQMCQDLIEIGVDVLHFYTLNLEKTTYGILDGLGYNVTGSADDSDEKTMVAKGSAWARV
GDKVKTTEGVEGTVTAIESDGTATIEFEGESPTVTLKKEDYSKVF
>A0A399W1D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia solanacearum|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRGILDTYREHGIRRLVALRGDLPSGMGEIGEFRFANELVEF
IRKEMNDTFRIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>A0A2N5TJ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia coronata f. sp. avenae|TrEMBL
MRKVAELIAGLKEDEVYFTFEYFPPKTIDGLSNLYARIQRMANLKPSCAHVTWGASGSTS
DTSLEIAAMVQDQLSIPACLHLTCTNIQRNHLDQTLTQAKQSGIVNILALRGDAPRGTEN
WFPTDHEFQHAIDLVKYIRKEHQDHFCIGVAAYPEGTSEFDQDQELSYLKQKVDAGADFV
VTQLFYDVDIFLNWVKACRKSGINVPIIPGIMPIQSYDGFRRLTALCKTNIPDSIHAKLI
PIKGDDQAVRDFGVELSTQMIKRLQVNGFKSFHLCTLNLERSITRLVNQLGWSPQGIKNC
QPLLGPSVTIGTSELVQGGLSVGWDEFPNGRFGDQRSPAFGLREGYSSSLTSAFSHLTTD
VHALWGTPTSLEDITNVFCAFTTGKLSSTPWSEEPLALETSSITPFLVRLNQNGWWTVGS
QPAIDGADSLDSVVGFGPAGGRIYQKAFVEFFIPQSHLEGLLSAVDEYNKNHPEGVAQLR
YYAGNCNQDQIRTNMAPSETNAVTWGVFRGAEVVTTTLIEAQSFKTWKKQAFDIWNDWAE
SFESNSANQRLLNEIEDSYWLCSMIDHDFKEAEHLWSFLIDQQQRLSTSQ
>A0A0T5NSG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius atlanticus|TrEMBL
MTGTSDTPSISFELFPPKTEAGVTRLRDTVAQLSAADPEYFSVTYGAGGTTRDRTARIVE
MVANRTGLPVAHHFTCVGASRAEIDRQAQAFWDNGMHRIVALRGDLPAGQSLPEDGYNDA
AELVAALRRKGDFDISVAAYPEVHPEARDAAADMDHLKRKIDNGAARAITQYAFDTDTVL
RFVDRARAAGIDAPIVAGIMPVANFEGLKRFSAGCGASVPDWMGQMFDGLDDAPETRAMV
ATGVAAEQCRRLMEAGITDFHFYTLNQPKVTLAVCRTLGLTPSIVAENAA
>I7ZI88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrocarboniphaga effusa AP103|TrEMBL
MPSPVSRLPSPGFSFELFPPRTPEGVAKLPATLKKLTEAKPGFFSVTYGALGSDQNGTYD
TLMTVVRETGIAVAPHLTCIGSTRARVAELLAQYRDAGVRRIVALRGDLPATAYSSSAPG
EFHYANELVSFIRQTHGEHFEIEVAAYPEMHPQSKRFDDDFGYFVDKVKAGADSAMTQLF
YNADAYFYFMDRCAKAGVGIPVVPGIMPITGFANIVRFCNNCGADLPRWITLQLEQLQDD
KAALQDFGTEVVTRLCETLLKGGAPGLHFYTINQAEPTLRLCRNLGLST
>A0A367ALG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. TBT05-19|TrEMBL
MNRALTIRDASTRASLRQTFQTLGYEVIPFKKTQEQVLQHVPRGVPLTVTASPAKGQDVT
VDLAVALAAAGYSVSPHFSAQQVRDRSHLADLVARCREAGITGAFVIGGDPTDVPTEFRD
AHALLVALHELDHGFTDIGIGGHPEGHPSVSEDVLFKALQDKASLATHITTQIVFDPAVI
LRWARELKRRGIDLPVHVGVPGSVSRQKLLRVSGGLGIGESAKFLKKQQTLLWRFFVPGG
YDPTKIIKGLAPHLGKPDNTLAGFHVFTFNDLEPTEEWRTRTLRNLS
>A0A839HXT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus rhamnosus|TrEMBL
MKISQCFKDHQVISFEVFPPRKNATNIAMRPILNTLDAVKAADPDFVSVTFGATGNKPHM
GTLEVAKLIKNEFNLEPVAHLPAAQLTRAQVDAELRGFQEAGIDNILALRGDIPKSGRVS
EDFPYACNLIEHIHQVGDFDVVGACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYQFRERAALAGINVPIEAGIMPVINEHQIERMATMAGVHLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A7U4TK88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. P2G3|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPTYFSVTYGAGGSTRSRTLDIVQALCA
RGETDIAPHMSCIGDDKTEIAELLTHYKSLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFEFDIDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTVVQPLVAGIMPITNSSNLMRFADSCGADIPRYVRKRLTDFGDDRKAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVEALGLTSQI
>A0A0L6JGD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. ARG-1|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTDEMEKILWSSIERLAPLQPKFVSVTYGAGGSTR
ERTHNTVARMIRETTLKPAAHLTCVDASREEIDAVVQAYWDVGVRHIVALRGDPADGVGH
AYKPHPEGYATTAELVEGIKRIGDFKVSVSAYPEKHPEAATLEADIDALKAKVDAGADQA
ITQFFFENEVYLRYLEKVRAAGITIPIIPGILTVQNFKQAANFARRTGASVPYWLAARFE
GLDNDVETRRLVAAAVAAEQVLDLVDEGVQDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
TEKAAA
>A0A6B4QCD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MNIKNLFKDKKVVFSFEIFPPKTTSSIQTIYDTLDDLKGLNPDYMSVTYGAGGSVKNNNT
IELSSLIKNKYGIEPVSHLTCINLTKKDVEYYLREFEKNNIENILALRGDVPIGSKITGE
LNHANELIKYISDNGKFNISAACYPEGHIEHKGLYREIESMKRKEEAGVSYFISQLFFDN
NLYYNFQDEVRAANINLPIEAGIMPVTNKRQIERILSLSGASLPDKFKRIMERYEHNPEA
LRDAGIAYAVEQIVDLISTGVDGIHLYIMNNPYVAKRISQSIESILLTVNQI
>A0A699YIL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haematococcus lacustris|TrEMBL
MKIVDKVNECIAKGQTVFSFEFFPPRTEEGVENLFDRLDRMAAYGPVFCDITWGAGGSTA
DVTLDIAKRMQNVVCVETMMHLTCTNMPLEKLDSALAE
>A0A7W9Z3R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. MP7CTX1|TrEMBL
MPSISFEFFPPKTDEQRAQLDRAAQLLKTHKPEYASVTFGAGGSTLSYTGDTVARLHRQH
GLNVAPHLSCVGGTRAELGALLDSYREAGYRRIVALRGDLPSGMATPGDFRYAAELVSFI
REHSGEYFHIEVAAYPEIHPQADDALADLHHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VRRLGVTVPIVPGIMPIANYSQLKRFSDMCGAEIPRWIAKRMQAHGDDAESVRGLGAEVV
AQLCRRLLQGGAPGLHFYTLNRAKATQSVLEQLS
>A0A1G5FW71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonlabens sp. Hel1_33_55|TrEMBL
MKITDHIKQAENTLFSFEIIPPVKGKSIKELYDNIDPLMEFKPPFIDVTTSREEFIYIEK
KGGLLEKKLTRMRPGTLGICAAIQNKYDVDTVPHLLCGGFTQQETEYLLVDCQYLEIDNV
MALRGDARKGDKRFECTEGGHEFAIDLVKQIDHLNKGHYLHDVIEISCDVDFCIGVAGYP
EKHEESPSMKTDLKRLKDKVDAGAHYVVTQMFFDNQKYFEFVNAARDLGITIPIIPGIKP
IATKSHLQLLPQTFHLDMPQNLVDAVENCKTNKDVRQVGVEFCIDQCRELLANDVPVLHF
YSMGKSDNIYDIAKAIF
>A0A2N0UIR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus bromii|TrEMBL
MKISSLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A1B7WXJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanizomenon flos-aquae WA102|TrEMBL
MPDTQSYSAFNNFRKASLTGEFLITAEVAPPKGGDMTHTIKMAATLKGRVHAVNITDGSR
AVMRMSSLVASAILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPQAKAVFDLEAVRLLQLIRNMNQGIDFNEKPLTDGKLDLFAGAAVDPQSRSWSGLQS
RFEKKIAAGAQFFQSQLITDFEILEKFMDKIACGYNKPVLAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEEGMKIAAEQVQMARGLCQGVHIMAVKREDLIAPILDLAGV
GKVS
>A0A551Z581|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis sp. M_QC_C_20170808_M9Col|TrEMBL
MTTRLQRAVQDREFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQIACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A139BTW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Gallionella acididurans|TrEMBL
MREQLFSFEFFPPQTTEGVEKLAVTRRQLAPLKPEFFSVTFGAGGSTQDRTLETIRQIKA
EGYSAAPHLSCVGSTRDNISAMLNSYRDMGIKRIVALRGDLPSGMASIGEFQYANELVSF
IRAQTGDQFHIEVAAYPEFHPQARSAQHDITNFRRKVQAGADSAITQYFYNADAYFRFVD
ACRKLGVTVPIVPGIMPIVKFAQLARFSDACGAEIPRWMRKTLEGYGDDNEAVQAFGLDV
VTQLCERLLAGGAPGLHFYTLNQAAPSLEIWKRLGI
>A0A1G1GNX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium GWC2_57_9|TrEMBL
MKLRDIFKTRSQGISFEVFPPKSEDGKDALLNTVKDLSGFDPLYVSVSYGAGGTTQERTL
MTLRWLRQETSLSLMSHLTCVGSSRASMDSLLREFQSLGVENILALRGDPPKSIPDFDPL
KGEFKYARDLVEFVRDYKAFSIAVAAYPEGHRESPSIEKDLEYTKQKIDAGADIAITQMF
FDNRYYYEFRERASRAGISVPILPGIMPIVDCRKMVTFAEACSTTIPQEILDRMEPVLDL
PEEMRKLGVEFAIRQCQDLIRNGVRYIHFYSMNRAETMRDILSVVRYN
>A0A349BY38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
CDFLTTQMFFDNLTMYNFLYKVREAGIQVPILAGIMPITNEKQVGRSVALSGATIPQKFK
RMIDSFGDDPARMQQAGIIYASEQIIDLISNGVSHIHVYTMNKPDVAAGILHCLSEFLK
>A0A4Q0A2D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dimargaris cristalligena|TrEMBL
MKQAPQTGGSEFAFSFEFFPPKTDQGLANLSARVTRMASLRPTFVGVTWGAGGSTAERSL
ELCQLIQDIQGVDVLMHLTCTNMDRTALDQALAAAKTIGIRNILALRGDAPRSTIPTQED
GSASSADLVGPLVHAVDLVKYIRQTYGDYFCIGVAAYPEGHPDASMTLANASPLSHSFGD
GATVSPSEVELQYLKEKVDAGADFIITQMFFDAQRFIDWYRASRSKDISVPIIPNILPIQ
QYQSFRRIAQLCQVHVPASVLSDLAPIQLDDSAVKAYGEQLALNLIRTLHRELRLDHFHM
TTLNLESSVSRIIAELRGVTPTGLNGPTNRVISASRARALVTSDARIQLVTGEGRPAASN
DSALVGEMINMPVSSRNQGKDSVGIVTTWDEFPNGRWGDSSSPAYGEYSAYGGSVLPITG
RQATSWWGRPTQLADLTSLFARFMQGPPEPSAAATAHTSAIQRGLLQLITERSILTIASQ
PPVDGQPSADPAVGWGPPGGLVYQKPFVEFFISATDYRTLQQTQFQNDPWITFLAGNKRG
EFESSGDDGNANMANAVTWGIFPGREVVQASMVDRDGFLAWKDEAFQIWDEWAKLSPPGS
ATERFLRATSEDIWLVNVVYNDFRAPISRMFESVFGLQLA
>A0A3B8U3R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
DQIEKIKAAGIENILALRGDIPEGMDFPTPRYFEHAVQLVEEIRKDYPEACIGGACYPEK
HPDASNKDEDIRHIKEKVDAGCDFLTTQMFFNNSIYYNYLYRLREAGVTVPILAGIMPVT
SRRQMERSIQLSGCVIPPELTALADRFGDSPAAMQQAGILYASHQIIDLIANGCGHIHVY
TMNKPEVAAGILNNLKGIL
>A0A3D0DPB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIIDILNKRNMSLSFEVFPPKKESTFESVVSATEEIAACHPAFMSVTYGAGGGTSRYTM
EIAKNIKDKYNVPTLAHLTCVSSSRETVRQKIQEMKEMGINNVMALRGDLTPELEASDSS
TWDYKHATELVRELKESGDFCIGVACYPEVHPESINQKDDLLHIKDKVDAGADFLTTQMV
FDNNLFFNFMYKIREIGVTVPVIPGIMPITNANQVARAIKLSGSFMPQRFKSMVDYFGND
PDAMKQAGIAYATDQIIDLYANGITNVHVYSMNKPDVAKSIMDNLSNILGKDFAR
>A0A3D4LV16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKITEVLKSDKVTLSMEVFPPKTTTAAEKVNEAVRDIAALKPHFMSVTYGAAGGGTSKYT
IQIAKDIKDAYGVNSLAHLTCLSSTKETVEKQITLMREAGIENILALRGDIPKETEFPLP
GQFHYAAELVREIKRIAPEMCIGGACYPEGHPEANSKAMDILHIKEKVDAGCEFLTTQMF
FDNSIFYNYLYRLREAGVMVPIIAGIMPITKKNQVARSIQLSGSCVPARFKSIVDWFGDE
PAKMKQAGIAYATDQIIDLIANGVKHIHVYTMNDPEVAVGIQRNLSEIIG
>A0A829MDF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus MAB_091912_2446|TrEMBL
MTTNPLDRDGPVAELQDPGSIADRLTAVQPGEIAFSVEFMPPRDEAAEARLWRAARVFER
YRPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEERLLRAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTARG
>A0A6V6Y2K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptoniphilus coxii|TrEMBL
MHIQDYFDHSHTKLSFEIFPPNERMTLKSVMAAASRMVGYEPDFMSVTFKADGSGGDQTV
QIAKAVTDIMGVPSIAHLTCSGIPKSELEDRLAELQEANIQNVLVLGGDSKRELGEDAYL
PYAKDMVRYFKERGDFTIGCACFPEGNNPALSMEEELDYLKEKVDAGADFLTTQMFFDNE
VFYRFLDAARAKGIDVPILAGIMPITAAGQIRRIADLSGAKLPRTLTDMVARFGDNKEAM
FDAGVTFAEHQMADLAARGIDGVHVYTMNKPAIPERIVNDIGSLFR
>A0A7L4G9A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alopecoenas beccarii|TrEMBL
MVNEAQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRLDSGDR
WFSLEFFPPRTANAAVNLISRFDRMAAGGPLFVDVTWHPAGDPASDKETSSMIIANTAVN
YCGLETILHMTCCNQTRDDITANLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDVCVAGYPKGHPEAESYEADLRHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A8C8S9F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelusios castaneus|TrEMBL
MVIEPHGASNGSTSSRSDGGSSSSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDKW
FSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKEEITGHLQKAKRLGLKNIMALRGDPIGEEWEDEVEGFNYAVDLV
KHIRCEFDDYFDICVAGYPKGHPEAESYKADLQHLKEKVSAGADFIITQLFFRSETFLTF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKEVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVPGLHFYTLNREVATMEILKHLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTSEESVFEVFTSYLSGEPNKDGHKVTCLPWNDDPLAAETSLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSENITALLKVLKTKKYELRVN
YHIVNVRGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEEESPSRMIIQYIHDNYYLVNLVDNEFPMENCLWQVMEDTFELLNYPTAQ
>A0A5D0CT04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus faecis|TrEMBL
MKPDLRERWENGVIVGDGAMGTYLYNFGFPVGISYEELNLLQPEVIGDVHRRYIDAGAEM
LETNSFSANYYKLSKFGLESQVEEINRAAVRIAKKASAGRAYVAGAVGSIRGGKRVNVTD
QELTRYYEQQMAALLNEEVDAILLETFYDLGEMRIALGRARHLTDVPVICQFAVDQVGRT
LDGYTISDAFGMLLGEGADVLGFNCHSGPKGIMSVMSRLGGPLNVPLSVFPNAGLADYVD
GEYIYGATPEYFGECSTAFADLGARLIGGCCGTTPEHIAATVQALAAYQAAPLREGKPLP
KPSETAVLTRSAEGTANGSSGNGRIPAITELVKERHTVIVELDPPRDLDIGKFMEGAAAL
KEAGVDALTLADNSLAVTRMSNMALGHLVQAELGLRPLIHIACRDRNLIGTQSHMMGFDA
LGIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNEGVAFSGKPLKQKAKFVVG
AAFNPNVKHLHKAVERLEKKIASGADYIMTQPVYDPELIVAIRQATAHLDIPIFIGIMPL
ASGKNAEYLHNEVPGIQLSEEVRRRMDGLQGAEGRAMGVEIAKELLDIAMEHFNGIYLMT
PFMFYEMNVALTRYVLEKSKPKAAHLSRS
>A0A7W5F8P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides albus|TrEMBL
MVTGRGRSLAELINEGERSFSFEFFPPKDEAGEEQLWNAIRTLEPYRPTFVSVTYGAGGS
TRDKTVAITGRIAAETELLPVAHLTCVGHTRDEVAGILDSYAAKGVEHVMALRGDPAEGP
RADWTPTPGGLDYAIDVVRLARERGDFRIGVAAFPEGHPSAESLETDADVLVAKAEAGAE
FAVTQMFFRAADYFGLVDRVRARGVDIPILPGIMPILNLAAIRRQSELIGAQVPEEIVER
LTAAGPEPADIRAEGIAVAAELCQELLDGGAPGLHFYTLNRSKATLEIFAKLNVTP
>A0A127ERI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoplanes sp. Z2-YC6860|TrEMBL
MPLTLLRQPLANERNETAPLVTAFLRHFSMEITRPSDADLIELKSVLPAKTPVYVPAIPN
SPLSELIAAATRLRAQGFEPVPHIAARRIESRAALEDLLSRLSRWANVRRALVIGGDVAT
AAGPFTSALELIDTGLLQRHGIVEIGIAGYPEGHLRLSTEALDRALVAKIEAAEQTGLAV
TIVTQFCFDAAAIANWIERLRALGIEHPVQIGMAGPANVAALMRFARLCGVRASARGLAC
QPGLVKHLLGVSTPDRIIRPLAESCGERALGRVSAHFFSFGGAAATARWACAAAAGRIVL
DRAGGFGVAPR
>M9MJH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter thailandicus NBRC 3255|TrEMBL
MMPAQTGPLPAISFEFFPAKTEKAAATLLENAKTLAAFGPQFMSVTYGAGGSTRDRTLAT
LKDMVRETGAPLAGHLTCVGASKEEVNAVAQAYWDAGVKHIVALRGDPPPSAGGVYEPHP
EGYAGAVDLVRGLKEIAPFEISVAAYPETHPAALNPQADLEHLRAKIDAGADRALTQFFF
EAETFLRFRDRAAAIGIERPIVPGILPIGSAAQAWKFAEMCGANVPKWMRDLFDGLDETP
QTRALVAATVADRLCQTLKAEGVEQFHFYTLNHADTASALCRLLGCRPL
>A0A1Q4AKL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 65-26|TrEMBL
MNGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFRTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVADRLERILHEDITETQVDLVK
TAH
>A0A2G4HZU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKITEHIAGASKTLFSFEILPPLKGAGIKELFSHIDPLMEFNPSFIDVTYHREDYILKKR
ADGSYDRISTRKRPGTVAICASLQNHFQIDAVPHIICGGFSKEDTENALIELNFLGIDNL
LALRGDAIHGETHFEPEKNGNKNALDLIYQIKNMNAGIYLDEEISNTNESNFCAGAACYP
EKHADAPNMQSDLKYLKRKIDAGAEFLVTQMFFDNAHYFNFVKSCRSAGITVPIIPGIKP
IATRKQLSALPKIFHIDIPEALTNEIDACKDDKMVGDIGVNWAIQQCKELMQQGAPVLHF
YTMGKSNQTKKICESIF
>A0A0M1J360|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromatium sp. WMS1|TrEMBL
MPDKNHQIFSFELFPPKTAEGLEKLKTQVAKLNKVEPRYISVTYGADSTTRKRTHATEDW
QRSQDNETATHLPIKDSQQQKICTFT
>A0A651D445|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARNPRFFSVTYGAGGSTQARTREVVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKVRALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLEGGAPGLHFYTLNQAAPVLKIVDNLTD
>A0A1Q4AJP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 65-26|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEDRLWDTVTRLEPLRPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDAVIREFADMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKGAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQKDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEVEAA
GSAAA
>A0A3B9H5V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVIDHINGSKKTRFSMEILPPLKGRSIQSIYDGIDPLMEFKPPFVNVTYHREEHVYKER
HDGLLQKISVRKRPGTVGICAAIMNKYQVDAVPHIICGGFTKEETENALIDLQFLGIENI
LALRGDPIKNETHFIPNKAGHKYAVNLIEQVVQMNEGNFLHEETGNSTATNFCIGAAGYP
EKHFESMNLKTDLKYLKDKVDAGAEFIVTQMFFDNQ
>A0A4Z1P774|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Venturia nashicola|TrEMBL
MFISSRLEEAEKAKKPTFSFEFFPPKTAQGIQNLYDRMDRMHGYGPTYIDITWGAGGRSA
HLTCEMVKTAQTALGLETCMHLTCTDMPVSKVDEALKEAHDSGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVTYIRKHYGDHFDIGVAGYSERCEDNEDVDQLVDHLKEKIDAGATF
IVTQMFYDADLFLDWVRKCREKGITVPIVPGIMPISTYAAFIRRANGPMRCHIPKAWLEA
MEPIKNDDAEVREVGMRLVTELCQKLLASGEIHHLHFYTMNLEKATRMIIEELGLMPDVG
SPVEKPLPWRQSLGLKRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFGEL
DAYGIGLKGSNEHYRKLWGEPQTIQDISHLFVKYVQGKIESLPWSEQPISQEANRITDDL
IDLNCRGILTINSQPAVDGAKSSDPVHGWGPRGGYVYQKAYLEVLVSPELIADVITKIER
DDDMTYYAVNKHGDLKTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEFFHLGQ
DWAECHPSSSPSRHLIENVMENWYLVNIVHNDFHETHGIFHLFDGLKVEDVDKPFDSPKV
SVREKTNGLSPVRATAAVNGASAITA
>A0A4D6YAP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MNHLYNSYKYLYQKIFDINSKIDISFEFFPPKIFNKENNNFLSSIKKLSIFHPNFISITC
TPRNSEINYTYQAIKNIPKTLNLNIAPHITYINNINTITKLSKKYWNNGIKSIVALRGDV
ISKEYNSEVYAFQLVTLLKKIADFDISVAAYPEVHPEAKNANLDLIHLKEKINCGANRAI
TQFFFDVNKYLKFRDRCISIGINVDIIPGILPIMNFQQLKKFINLTNVYVPSWINNIFNN
ININNIHINKMIGLVICVDIIQKLCKEGVNKFHFYTLNDFEIVYTLCSILKQNIKIN
>A0A4R8MSX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira meyeri|TrEMBL
MNQILLEVIPRDVQTLLSEVSFVKNNFSQISGINIPDLLRFETRSWVAASKIQNVFPNVI
PHLRAIDFDLDHCGHIIEFLQKNSISSVVVIKGDPPTDMSQKVYPTTSIKLIKKLKKEMS
SLKVYAAVDQYRSGIKDEFDYIEMKIDAGADGFLTQPFFDLRLIHIFTEKLRGKEVYIGI
SPVTNEKSQSYWESRNRAYFPRDFQLTMDWNVQFAKEVIDYCSKNHFNMYLMPIRIPLET
YLRGIFK
>A0A1Q9XL06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. PA27(2017)|TrEMBL
MSQKRPNVSFEFFPTKTDAGHEKLLNTARELAGYNPDFFSCTYGAGGSTRDRTLNTVLQL
DSEVKVPTAPHLSCVGDSKAELIELLNLYKSKGINRIVALRGDLPSGMGMSSGELRHAND
LVELIRTETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADCYF
YFVERVRKLGVDIPVIPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDAQSIQRF
GEEMITGLCERLIEGGAPGLHFYTLNQAAPSLAVWKNLQG
>A0A3B9H6H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
KGIDVPIIPGLKPITTMKHITFLPKFFHIDFPEELSSELEKCKTNDDVRQVGIEWGIQQS
KELVDYGVPLLHYYTMGKSQTVKAIASEIF
>A0A3D6DDM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MTITEILSQPGHSRFSIELLPPLKGQNIDSIYQTMDALSPFNPAFVDVTYHREEYVYREV
GPGLLQKRTVRKRPGTVGICAALMNRYEIETVPHIICGGFSVEETENALIDLDFVGVRNV
LALRGDAIRSEGRFKAEPEGHAYAIDLVDQIVSLNKGVYLDPDLRNTTATEFCIGVAGYP
EKHFEAPNPDNDLRWLKKKVEHGAEYIITQMFFDNTRYFEFVDRCRAEGINIPIIPGIKP
LTTSSQLQILPQVFHVDLPEALVESVEAAKTREQVKKAGMDWCTEQAAELLEKGAPTLHF
YTMGKAHPTAEIARRVFGS
>A0A7D5DBD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas eucalypticola|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLNVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKADLRALLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIRAESGDHFHIEVAAYPEMHPQAHNFEDDIKNFVRKANAGADSAITQYFFNADSYFH
FVERVQKAGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDVTSIQRFG
EQVITQMCEQLLEGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A6N4AMG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. 45_250|TrEMBL
MKIKDLYTPGRTVFSLEVFPPNKNFPIETVYDAIEGLAAINPAYISVTYGAGGNRANRST
CEIASHIKEKYGIESMAHLTCINSTRDDVDFMLDDFAANGIENILALRGDNKPDEEPKND
FPHASDLTAYIASKGNFDIAGACYPETHVDAESAEEDIKNLKIKVDAGASHLVSQLFFDN
SCYYDFEKRARAAGIDVPIAAGIMPVTNKKQIERMVTLCGASLPSKFVKMMQKYENDPEA
LRSAGIAYAIDQIVDLISNDVQGIHLYAMNNPAVASRIYNGIKDLL
>A0A5R8Z329|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mosselii|TrEMBL
MSLLKQALDEGTFACILEFVPKPSAARFATLETLMDRTRLGDWPLTVAIGDRVGSALDLS
PLDAYTSLSTPRPALLHFSGKDRERRDLLAQLQRMDAAGLDQLLLLTGDRLPGHTPGERP
VRYLESVAALQIVRQARPHWLLAAALNPFKYQEAEGGAQYLKAEKKLSAGADLLILQLGF
DMHKHQEALDWMRRQAQPKPLIACIMALTEGRAAMLDHVAGVTVTPSMHALLKAESSVSK
AYAKQRANQRLALQVIGLRLMGYAGVHLSGIHEIEQFEALEQAISELQPNLRQLDQWAAA
WQAAWQAPNLAPVTFHPTGHAWRLGQRQIDASRREKARYHLLSALHHQLFSRTTTLSKAF
GWAVTRPLWRGPAAASWLHTLERRIKRPLVGCDTCGSCRLEDTLYICPETCPKGLANGPC
GGTRLDRCEFGDRECVHSAKYRLAVGVGRTEVLAERLIPCVQVENRQRSSWPVWFTPPPA
HEHPAHKACSAPPEVSG
>A0A7K3DVT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5785|TrEMBL
MPLLARLSGLPRPGGPGQDRGAAVAGADRGGPLRGVPAPPRAVHGRPRRPPPRGRLLQRG
DRAMTTFSFEFFPPRSAAGERTLWDTIRRAESLRPDFVSVTYGAGGSSRDRTVDVTRRIA
RETTLRPVAHLTAVGHSVAELRHVIGCYADAGIRDVLVLRGDPPGDPRGAWVPHPEGFTY
AHELVALVRSLGDFRVGVAAFPEGHPRSRDPESDLRHFVAKCRAGADYAITQMFFDVEDY
LRLRDRVSAAGCDIPIIPEIMPATDVRQITRFAELSDAAFPEHLAHRLEAARHSPADAFR
VGVEHATGMAERLLAEGAPGLHYITLNKSTAAFDIHRAVLASRSLRAR
>A0A7W5YLS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK591|TrEMBL
MMHNIDMAEDALAVRPVMSPRAALIDGYSFEITGKDTAGLQDVSKLLAPATCVSIAFIPN
ENHDARLAAAATVKELGFHPVPHISARRLGSAAELDRLLALFVSVANVDRLFIVAGDPDV
PVGPYEDSLAIIRSGLLSKHGIRKVGIAGYPEGHPKIRDGVLFEVLQEKHALLTAAGLEY
DITTQFSFEAEPVIEWIGRLRQAGITAPIRIGVPGPASVKTLLRFATICGVGASTKVMAK
YGLSIRKLLNTAGPDALVAEFIRRLDPSKHGSVCLHFYPFGGVGKTAEWIRDFLASHISK
>A0A7S1UAM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeomonas parva|TrEMBL
MRIAEKIARLEEVGQAWFSFEFFPPRTQAGVENLYARIDRLASLEPLFVDVTWGAGGSTK
ELTLQIAETTQKYSGVDVLMHLTCTGLTKAELKQIVQEARDKGLQNILVLRGDPPKGRTW
KAVENGCDHAVDLVRLIREEHGDYFSIGVAG
>A0A292SG61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Gastranaerophilales bacterium HUM_20|TrEMBL
MIGIKVVRVKVRAIPVKAKHIITSAIKGTCIYLTTQTPTTDASETSKNIFLLLLFQGCLS
EIQAPIVSATISGKIISFSPLISAIATINMVITSANIYLPNLILFKTAVFILIKLYIKNS
CYNLFMKLREIYNNNKTVISFEVFPQKDDEAKLLEEITILNKYNPAFISLTCGAGGKENK
SFELLKDIQNLGINVMPHFTCITSSKKSVEEGLKEIENIGIENILALRGDIPENTELRHY
DFNYANELVNYIKAKTNLSIGVAGYPEGHVESPDIKSDIINLKKKVEAGADAIFTQLFFD
NNKFFEYVQLVRNEGINIPIIAGIMPIKSYKQIVKMTSLARVAIPENLQTKINKYKEDSK
SMTELGIEYASKQCEELINNNVMGLHFFTLNKSYSTSQILNNIL
>D7V0J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria grayi DSM 20601|TrEMBL
MNLRRDLNEKVLIADGAMGTLLYSYGIDRSFEELNLSHPDDVSGIHRAYIEAGADIIQTN
TYGANYIKLSRYGLEDEVKKINQAAIRLAKEAARGTGTYILGTMGGINGSSDTKLPLASE
EEVKRSFREQLYCFLLEGVDGLLLETFYDVDELKTVLKIVRETTDLPVIANVSMHEPGLL
QNGQQLPEVLKELEALGADCVGMNCRLGPYHMARALETVPILQKSHLAVYPNASLPEVRG
GKVVYHTETEYFQNYGEIFRQEGARIIGGCCGTTPEHIRALREGLKSFEPVTSKKVRPII
ELVPAEKLEDDGEERLLDKVKREHTILVELDPPRTFDTDKFFEGAEALHENGVDAITISD
NSLASPRISNMALASILKHQYGIKPLVHLTTRDHNLVGMHSHIMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKYNAGISYTGKSLKEKGRFHVAAAFNPNVLNVEK
AVKLIQRKVEYGADYIITQPVYDKEKIAILKDALQKADIKVPLFIGVMPLLSGRNAEFLH
NEVPGIRLPNEVRERMREAEAADRSKEEGMKIAKEIIDSIYTEFNGIYIITPFLRYDLSV
ELATYIQNKKETHVLEK
>A0A8E0V6Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp|TrEMBL
MKDVREILKKRPLLFDGGMGTYYKAAPGQECEQANLLDPEGIQAVHRAYLAAGADAVKTN
TFGLPRMAAAQNPVWEALADEGWKLAVQAAAETGAAVFADIGPAPDTEAQPAAQLYIALA
DRFAALGAKNFLFETLSTDTGVTEAAQHIKKTVPDAFILVSFAVLPDGYTREGRHCAELV
RRMTESGVVDAVGLNCVSAPGAMRALVQRLGGTKLPLSVMPNAGYPVVTRTRVQYQGRPE
YFAQELARIAAECADVRILGGCCGTTPEHIAALRTALDALPEALPAAPVAEVSTPAKPEV
EKDDAFLRKLNAGKKVIAIELDSPKDADLTGYLDGARRLQAAGADLLTIADCPIARARMD
SSLVACRVHRELGLNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDE
VKNVYQFNSRKLAQYIVSLAGEGREMPSPMTVFGALNLNARNFDVELRRAVEKMENGMSG
FLTQPVLSAQAVENLKKARETLGEKAKLLAGIMPVVSQRNAIFMENEINGIHVEQAIIDR
FAGLDRAQGEELGLEVSVQAALAAAPYADGFYLMTPFNRVALMERLIARLKEEVIAD
>R4WJ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia insecticola|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRATRAELKKLAPKFVSVTFGAGGSTQQGTLDTVLEMAA
EGFEAAPHLSCIGSSRENLRAILAQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQEHGDWFNIEVAAYPEFHPQSKSPRADLENFARKVKAGANSAITQYFFNADSYFKFVD
EAKKLGVDVPIVPGIMPITNFSQLMRFSDMCGAEVPKWIARRLESFGDDRESIRAFGVEV
VTGLCRRLIDGGAPGLHFYTLNGAWAARTVCEGLGFKSA
>A0A4Y9H3X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella sp. WM03|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMETMLWESIHRLKVLEPKFVSVTYGA
NSGERDRTHSIVKSIKQETGLEAAPHLTGIDATPEELKQIAKDYWDSGIRHIVALRGDEP
QGYEKKPFYAADLVELLRTVAGFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDNYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPTWLSKAYEGL
DDDPTTRNLVAASVAMDMVKILSSEGVNDFHFYTLNRSELTYAICHMLGVRPRG
>A0A1F7SH08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Schekmanbacteria bacterium RIFCSPLOWO2_12_FULL_38_15|TrEMBL
MSLKNLFEKGKFVLTAEVEPPKGTDVSKIFEISESLRGKVDGLNITDQQSAVMRLGSLAS
CHLLIEKGFEVIFQVTCRDRNCIALQSDLLSASVLGIENVLILTGDHPQLGDHPDSKPVF
DLDSVQLLQIAKTLEGGHDFVGNKLMKEPNFFLGAAINPGADPIEPEIIKAEKKVKAGAS
FFQTQAIYDSEKFKQFIEKTKHLNVFIMAGIVLLKSAKMARYMNEKIAGVCVSDDIIERM
EKADDKRKECIEISVSIIKGIQDFCHGIHFMALGWEDLIPEIIKRLNLGK
>A0A2P7BTM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium brassicacearum|TrEMBL
MTKIAASIEVAARQAIESQDLPGLFPAGTRVYITDMGTDSVDTLTSAAKRIHDLGYKPVP
HFASRRLSTKAALETRIRRAAEEAGVTDILVIGGGLERQAGEFSSTMEVLETGFFDKYAI
TEMGVAGHPEGSPEFSEAVAIEALRLKQNFGERTGAKLRVVTQFGFDADRFIRYSESLRE
HGVDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNALSLTALATSHSPEGVVGPIE
QHTIANPASAIKQIHIFPFGGLKKSSEWLVDRGSWAVHNASHTSANAAAS
>A0A0C1F3R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. AED|TrEMBL
MKVTQHIEDAKGSTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVN
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKEGGNDFAVDLVKQINQLNCGKYLHDVMDIDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVEAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVGQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A3G6RWW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. G0162|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWSIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A373KY86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF42-10|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYITSQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A6N8BQ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp|TrEMBL
MHIGQMIRELSAPFYSLEFFPPSDTAHLPDFYATVDRLRALNPLFASVTYGAGGARQQNT
LAVTAELARRGIAAMAHLTCVGAEPQSIAAFLNDLRASGVNNVLALRGDPPADKAWNWSS
AHFRHASDLVAFAREQQPGMGIGVAAYPAPHPESPTFSQDRLHTANKLRAGADFALTQLF
FDAREYEDLVSHLRGQGITTPVIPGILPIQSFDSLRRVLSLCGANIPGKLYLALEKAHNE
GGAEAVREVGLDYAVRQIRSLLDAGAPGIHLYTLNKADMCLRLAEAVGTL
>A0A7V8H117|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CES|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A8H3B6Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKLTEKLATYRSDTPYFTFEFFPPRTDQGYSNLLTRISGLASLKPVATSVTWGAGGSTRD
RSLDLAGFCQADNDLDTILHLTCTNMEKGTIDEALMTAMERGVSTVLALRGDPPRGEEYW
IPTDPRFQHAEDLVTYIKQHPTFASHFCVGVAGYPDGHSEGGSEEEQLTHLKRKVDAGAE
FIITQLFYDVEKFKSWLRKVRSTGITVPVIPGVMPLQTYATFTRMTDLCKATVPLHIQAN
LDAIKHDDQLVKEYGVSLAVSMIRSILVDGDVKGVHFCTLNLEKSVRKILDELGWTHESL
HHNQIIIDANQSPHILPSPADAPHPTTFTISPSEAAQHANTSLAEHTRTGTLRTAAEAID
SGWDDFPNGRFGDSKSPAFGLIDPWDGGGLGVPPHVAIAQWGRPTTEQELSDLFLAYLND
TTSTTPFSPEPLSDESATILPHLVSLTKKGLWTVASQPAVDGALSSDPVIGWGPRDGRVF
QKSFVEFFATEADLEKVAQAIEDSGDGWLTFFAGNNEDGFLTNIPDSGSNAVTWGVFPGK
EIAQPTIIDRDSFLAWKVRPIYVNAQEHRTKLGQDDAFMIWHDFGLCYPPDSPTRKLLED
VINTRWLVNIIHHDYKNSNALWDFLAKYLE
>A0A4R1K102|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Celerinatantimonas diazotrophica|TrEMBL
MSFQTAQQLENLNQKLSELNDDIRVSFEFFPPTTAAMETTLWNSVERLKILEPSFVSVTY
GANASTRDRTHTIIKEITKRTTLKAAPHLTCISTSADELKQIAQDYWDNGIQQIVALRGD
LPEGSDKPKVYAEDLVRLLKEVADFDISVAAYPEVHPEAKSAQSDLLALKRKMQAGASRA
ITQFFFDVESYLRFRDRCVAVGIEQDIVPGILPVSNYKTLCKFAGFTNVKIPKWLHQQFE
GLDDDQTTRNLVGASIAIDQVKVLSREGVKDFHFYTLNRSELTYAICHTLGVRPTSMIE
>A0A7X9IHJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp|TrEMBL
MKIIDLLKRDEPFVSLEFFPPKEKSAWPGFFDVVNWLKPANPLFVSVTYGAGGSTQANTL
EIVSRLKREYGLEPMAHLTCVGAAEKNIRAFLDALVDAGVDNVLALRGDPPRGQTDFVPD
SEQFRYASDLVAFIRAEYPALCIGVAAYPEVHPQAESPEKDLEYLKLKVDAGGDFAVTQL
FFDNRRYFDFVARARAAGIGVPMLPGVLPVVSLAGVKRMLSFCGASIPPDYLRSLEEADA
AGSNAAVAERGVAYATAQARGLIDGGAPGVHLYTLNKAEACLKIVGGLGL
>A0A8H3B3V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MRGLGPEFVDITWNAGGRTSDLTSELVKTCQGTIGIETCMHLTLLLFTRFDTGLTSFILT
QEAKANGCRNILALRGDPPSGQEEWTSVEGGFQHGIDLVRHIRREYGDYFDIAVAGFPQT
IQLPEAEAKQEMQWLKEKCDAGANFIFTQMFYDAETFIRWVKAAREAGITIPIIPGINPI
QTWNGFIRATSLSGTEIPKDLMDTLEPHKNNDEKVRELGIKIVADLCRKILDADIGIKGL
HFYTMNLEKGTKMLLEELNLVPRVETIKPLPWRQSLTPTRRTESIRPIFWANRTKSYLSR
TENWDEYPNGRFGDSRSPAYGELDGYGIWIKQTPEEGRKIWGTPTTMDDIKTLFAKFCSQ
ELKALPWSDQAPSSEMLVIGQQLRRMNELGYLTINSQPAVNGARSDDKAFGWGPKNGYVY
QKAYLEFFVHPDQLQTLIKRIERDTNVTYYAINKQGDLKTNSTSDGPTAVTWGVFPGKEV
VQPTIVEAVSFMAWKDEAFELGCQWAKVYEPGSPSRKLIEGIMDEYFLVNFVHNDFHDRE
AIFRPFFVDAGLKVNGDAETPVANGIKQVNGLVNGHTTVSA
>T0V349|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HSISM1|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKREAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKDLFAHQPNFEVN
>A0A1B9KUA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNQKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFSKTEMQKILHDLKCAGIDNVLALRGDISPNVQPKDDF
RYASELVSFIKESGDFNIVGACYPEGHLEASTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKARDMGVNVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGVHLYTMNNSYIARRIIEAVATLLAVPKLK
>A0A0N1LNW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. AAP83|TrEMBL
MELESHVSILNDYSLEMTAKERPELDNAAGRILPGTQIAVAFLPNEDMESRIAAACHVRS
LGFEPIPHISARRMRSAAELSDMVERCAQYAGVKRVFLVAGDPVRPDGPFEDTLSMLRTG
VFESNGIESVGIAGHPEGHPIMDANRLASFMDRKVDEIGARGMASTLVTQFSFDAQALLD
WHFSLRERGISIPVRLGVPGPAGVRRLLRYAAFCGVGATTSVLKKYGISLGKLIGLAGPD
RLVSELEQGLIAERSDNLALHFFPFGSLGATADWISTYPHNKGLAA
>H3NWK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium HIMB55|TrEMBL
MSAVKQLLESLYFEVIPMKGFEDKLDVLKAGDRVGITCSPKQGLQVTLDTVAKLSDRGFS
LTPHLAARQVKNKQHLKDIVSQLTDSNITSIFVPGGDLDEPMGEYDSSAAVLQDLAEMDH
PFTRIGVASYPEGHPAISDDLLFEALAAKQGIATHMVTQMCFDMPVLVKWLSEMRDRGIT
TPVWIGLPGVMDRMRLFKTSLRIGVGQSAKYAKKQKGLIGMFLRSPTYKPDSLLKELKPA
MNDERMAIEGLYMFTFNQIDNTVQWSQEQLQRIK
>A0A1J5VSQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. NML120713|TrEMBL
METRISASAPLDGIEEELAPRPQRARTALSFEVIPPRHSADSAKLDALIQGLAAYQPDYV
SVTSSHRSDWLEGTARLIERIAQTTSMRPIAHLACTAGTPDELRQWITQLIDAGVRGFLA
LRGDIPAGLDRLPDTHLQHATDLLNLIQDVADAQAYRLAAGKLALSVACYPRGHAESTSD
DQDLDVLLAKQRLGADFAITQLFFDAQDYLSFAERARLAGVRIPLIPGIMPMTSVNRVRR
MGELSGVAPPVDVIKQLEAARTPEEEHQIGMRLTVELARTILQAGAGGLHVYTHNDLAVT
RELLKGLNL
>A0A554TNU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. KBS0710|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTFSTVLQLE
NEVKVPAAPHLSCVGDSKAELRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITQMCEQLLQGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A2X0MLS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbotryum silenes-dioicae|TrEMBL
MRRSAVRRRWAASQPELVKISEKIAKAERDGRPWWSFEFFPPRTPDGWANLYDRIERMKQ
LGPIFVDITWGAGGATSEATTTFVKHAHSELGLETCMHLTCTNMPVSMVDAALKDAYDSG
CRNILALRGDPPRGSEEWVQTEGGFNHAIDLIRHIRKHYGDYFDIGVAGFPEGHPQAESA
ELEMKHFKAKIDAGANVVFTQMFYDANVFINWGRRVREAGITVPIVPGIMPIQTFASFKR
RTDFAKTIVPQELWNLLEPIKDDDLKVREVGTKFVADMCRKVLTAGIGINGIHCYTMNLS
RGTEMLLEEMNFVAQADIVKPLPWRVSLTQKRRTETTRPIFWSNRTRSYLSRTADWDEFP
NGRWGNQASPAFGDLDSLALSLPHKAQDATTLWGEPTSFGDVAQLFARFCTGDLKALPWS
DQPVARETTVISEPLKKINSAGFLTINSQPRVDGAGSSDPVHGWGPRGGYVYQKAYLEFF
ASSAHLEDLLKVLQRYPSMTYHAVNKAGDLQTNAAPGPNAVTWGVFPSAEVIQPTVVDGT
AFLAWKDEAFELGTLWAELYSKTRQESAKVISEIFDTFYLVNLVQNDYRDVDELAIFKPF
FEVIDGTKTATANGVNGSH
>H3NXP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium HIMB55|TrEMBL
MAIPRVSFEFFPPKTPAGLQGLMQVADRLRAFDPEFASVTYGAGGSTQETTANAVRSLRA
SLGLDVAPHLTCVEATREETLAIAQSYVDSGVRKIVALRGDPRDGVSGTYKPHPDGFAYA
SDLVGGLSAFAGLDIYVSAYPEKHPAASSLDFDIEVLKAKQQNGATAAVTQFFFNNDDFL
RYRDKAHAAGVSIPLIPGIMVPENIEGVCRFAAACGASVPGSLLERFTGLNDDAETRRLI
ATHFSIEQCEALGAEGVDQFHFYTLNKSESVYAICHALGLRSSLSEAA
>Q57HA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella choleraesuis (strain SC-B67)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>J1GVD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 335 str. F0486|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEDLIKAVESCKNNNEVKQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A1I7B325|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lishizhenia tianjinensis|TrEMBL
MKVIDHIKEAKETLFSFEILPPLKGKNVQSIFDGIDPLMEFKPKFINVTYHREEYIYKER
GQGLLEKIAIRKRPGTVGICAAIMNKYQVDAVPHLICGGFSKEETENALIDLQFLGIDNV
LALRGDSIKTESSFRPHENGHKYAVELINQITDMNKGTYLMDDIQLEPTDFCIGAAGYPE
KHFEAMNLSTDLQYLKQKVEAGAEYIVTQMFFDNKKYFDFVEECKKAGINVPIIPGIKPL
KSMNHISFLPKFFHIDFPDELSAELLKCKTNDDVQALGIEWAINQSKELKKAGVPCIHYY
TMSKSDDVKLIANEIF
>A0A1I1Y3J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus algorifonticola|TrEMBL
MGEMNSKPDLRSAIAERILTGDGAMGTFLYQMGFPVGVSYEEFNILRPDVIENVHRRYYE
AGAQVIETNTFSANLEKLSIYGLEAEMEAINRAGVRIARAASGPDAYVVGAVGSIRAGKL
KNTRTVRVSDAYERQMAALLTEGVDGFMLETFYDLDEMLLALRIARKLTDIPVICQFAVE
DVGRTQDGVSLRQAFDQLTEEGADVVGFNCRSGPNGIMRAMKAIEGEATWPLSIFPNAGI
PDYVDGKYTYAATPEYFAASAREFADYGARIVGGCCGTTPEHVAAMAAALNHYSPQSGSQ
AVGETAVAEVETLVINEQPPVKLEIPDVIVPTEPNIVDKVRERHTVIVELDPPRDLDISK
FMAGAAALKACGTDAVTMADNSLAVTRMSNLALAALVQEKVGLRPLVHIACRDRNLIGTQ
SHLMGLDALGIDHVLAVTGDPARFGDLPDSSSVYDFTSFEMIRMTKQLNEGIAFSGKPLK
QKANFIVGAAFNPNVKHLDKAVQRLERKIKSGADYIMTQPVYDPALIKQIAEATSHLPIP
VFIGIMPLASGRNAEYLHNEVPGIQLSDEVRQRMAGLEGEAGRAEGVRIAKELLDEAVLH
FKGIYLITPFMFYDMAVQLTEYVWEKTGVHR
>A0A895XLR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronoglycomyces albus|TrEMBL
MTLGTASVLPHNTPAIGDLLRRGPVRYSFEFFPPKTPKGQATLWRSIRRLEALRPDYVSV
TYGAGGSTRATTVETTDRIAAETTLLPLAHCTAVDHSVAELRNLIGHFVNVGVRNILAVR
GDPPGDPQGRWVQHPEGFLHARELVELIKSSGDFSVGVAAFPEGHPRSPDWDTHVRHFVE
KCRSGADFAITQIFFDWQDYVRLRDAVVAAGCDIPIVPGVMPVTNVNQIERFAQLTGMGF
PPQLAQRLRREADSPEAVRAIGVEVATELSQKLIAEGAPGIHFITLNHSDSTRKVWANLV
SPQAKLVSHL
>A0A836W5L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrodictium sp|TrEMBL
MKILGELEPTKNNEKLAKRVEKLAGVVDAIDIPEAPMGKPIAHAAILAAYIKAKYGIDAI
PHVRVSDLNTVGLLSILGGLKATGIEEAVLLKGDPPIVGK
>A0A839IXU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propioniciclava sp. MC1595|TrEMBL
MPETIVDRLRSSDGPTFSVEFFPPSDDAGVLQLIGTVDQLQGLQPDWVSVTYGATGASRY
KTFSAVGAIRGQTAVSTMGHLTIAGQSAAEVVRAIQAYERLGVTHILALRGDPPSGGRFA
PHPEGLRTATDLVRLVKSLGDFTVGVAAFPDGHPEGDLDLDARILLAKEQAGAEFAITQL
FFDPAAYVSLVGRFRALGGTMPIIAGIMPVTVPSQIERFAGLSGSAMPADFEARLRAVAD
DKAAFRAVGIDLVTQLCRDVLDAGAPGLQFFTLNRSTATAEILGRLRAEA
>A0A7X0X5X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria immobilis|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGATDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLNELKTVLKIIRETTDLPVVANVSMHEPGLL
QNGQKLPDALAELITLGADVVGINCRLGPYHMARALETVPLYEHAYLAVYPNASLPEMQE
GKVVYQSDTDYFAHYGEVFRQEGARIIGGCCGTTPDHIKALRDGLKTTKPVLEKEVRPIL
ELVPEEAVDEELGERLLDKVKERFTVLVELDPPRTFDTTKFFEGAKALDEAGVDAITISD
NSLASPRISNMALASILKHEHGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKIKLLKEALQNANITVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEKGRANEEGMELAYEIMDSICDHFQGIYIITPFLRYDLSI
ELAKYAQKKQQIPIVSK
>A0A1U8K9S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium hirsutum|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFDRMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTTMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFIKFVNDCRQMGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQFPHGRWGDSRNPS
YGALTDHQFMRRRARDKKLQEEWATPLKSIDDIQEKFKSFCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSLSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGTTDVNAVTWGVFPAKEIIQPTVVDPASFMVWKD
EAFEIWSRAWAALYPEGDLSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>A0A1S2QTU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. MUM 116|TrEMBL
MSFLEKLKNQILIADGAMGTLLYSYGTDCCFEELNLSHPEQIQHIHKAYIEAGADVIQTN
TYAANYLKLGRYGLEDSVKEINSAAVRNAKLAAGQDAFVLGTIGGNRGIKTNSITIEELK
RSFREQLYCLLLEGVDGLLLETFYDLEELETVLTIARKETKLPIISQISLQEPGFLQDRT
PVNDAIKRLEGLGADVIGLNCRLGPHHMLLALEQIELPAHAFLSAYPNASLPAYTDGKFH
YEGDAEYFRKSAQSFRKEGVRLLGGCCGTTPEHIKAFASELKNAVPIVEKVVKLKPEKIK
VEDRTPERENPPLEKIVRERPSVIVELDPPRKLDSTNKFFEGAKALKEAGIDAITLADNS
LATVRIANEALGYRVKTELGMRPLIHLACRDRNIIGLQSHLMGLHTLGMNDVLAITGDPA
RVGDFPGASSVYDVSSFELIQMIKQLNKGLSFSGKDLGQKTDFSIAAAFNPNVRTLEKAV
KRLEKKIEYGADYFITQPVFSEEKLIEVYENTKHLSAPIYIGLMPLTSSKNAEFLHNEVP
GIKIADSIRDRMASLNDQPQQAVREGIAITKSLIDTALDLFNGIYLITPFLRYEITAELA
AYTNQRANEIRGNIYVESTIH
>A0A7K8NIA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Casuarius casuarius|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDK
WFSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRIGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKDQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6G0XZS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphis craccivora|TrEMBL
VITAPHLTCVDSSPIELEKIAKFYWKNGIRSIFALRGDSNNTDHSHRMYAYDLVMLLKKI
ANFDISVAAYPEVHPESPNAQLDILNLKKKIDAGANRAITQFFFNTESYLRFRDNCIKNN
INVEIVPGILPIYNFEQLKRFAKMTNVKIPSWMFEIFDKLTDDVMSQKIIGASIIIDIIK
SLSEEGVKNFHFYTLNQSDIVYSICRLFGF
>A0A5D3EIZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides pyogenes|TrEMBL
MRVIDLIHNNTKTAFSFEILPPLKGTGIEKLYEDIDTLREFDPKYINITTHRSEYVYKDL
GNGLYQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFSREETEYVLLDLQFLNITDL
LVLRGDKAKHESSFTPEKDGYYHAIELQEQINRFNQGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMEADLYWLKKKMEAGAEYAVTQLFYDNKKYFDFVKQAKAAGIHIPIIPGIKP
FRRTSQLSMIPKTFKVDLPEDLVKEVLKCKNESEVEQIGIEWSVNQCKELMSFGVPSIHF
YSIGAVESIKEVAKLIY
>A0A417V5B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium OM02-26|TrEMBL
MKISEILKNKSTISFEVFPPKNKEGDISSIYSTIDGLAKLSPDFISVTYGAGGSTKGKTV
EIASVIKHEYGIESVAHLSCISSTKEDIKYECERLKEAGIDNILALRGDYPADAADFDPE
NLEFHYASELNEFIGEHFKGQFCLSGACYPETHQEADGFKKDLEALKKKVDAGAEYLVTQ
IFFDNDYYYRLVREARKIGITVPILAGIMPITNAKSLIRTTKMCGCTIPYQLSTMIEAHY
DNPEAMKEIGINYAAQQIIDLITNGVDGIHIYTMNRAETAQRVFESIPAVLKELN
>A0A0M8VFD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MMG1121|TrEMBL
MNPALTVPPAVGAALLDDFSLEMTGKDVPRLEEAQGSIPRGTRVNITFLAGEDLGMRLSA
ARAVKRLGFVPVPHISARRLPSRTALEEFLSGLAEDGTAENVFVVGGDPARPEGPYEDAL
AVLRTGLLQRHGVRHIGISGYPEGHPAIADGTLWSALTDKSAALRAERFGGDVITQFGFD
VEPVLTWLEAARARGVHLPVRIGVPGPAGVRRLLGYATRFGVATSASVARKYGFSLTNLM
GTTGPDRFLHTLAHRYDPERHGTVKVHFYTFGGLRHTAEWIAGFRQTALGTTAG
>A0A085B4G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium acnes HL201PA1|TrEMBL
MAPDFILVTYGASGSRCDRTLRCTQHMVSTGLRTVGHLTCVAQSVADVEQMVADYAESGI
GHILAIRGDMLGGVGQPWVTHPWGLPNATELVRLVKRVHPEACIGREGA
>A0A375EL29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus taiwanensis|TrEMBL
MRAAPTRRATIMQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQ
GTLDAVLEIQREGIEAAPHLSCVGSSRESIRAILQQYREGGIRHIVALRGDMPSGMGEIG
EFRYANELVEFIRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVKAGADSAITQYF
YNADAYFRFVDDVRALGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDD
RESIRAFGLDVVTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A2G5HK09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cercospora beticola|TrEMBL
MHITEKLQQAHGKGKATCSFEYFPPKTAQGVQNLYDRMDMMHGLGPAFIDITWGAGGRHS
SLTCEMVKVAQTAYGLETCMHLTCTDMERSKIDDALKEAYKAGCTNILALRGDPPREQEK
WEATEGGFRYAKDLITYIKKTYGDHFDIGVAGYPEGVDETCGADEHITYLKEKIEAGGTF
IVTQMCYDADIFIDWVKKCRAAGIPESVPIIPGIMPISTYAAFLRRANWTKAHIPEHWME
KLEPIKNDDSAVRAVGCDLIVEFCQRLLDFGLMHLHFYTMNLAQAVKMVLEKLDMIPEAE
SPHPDIKPLPWRQSLGLNRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
GLDEYGIGLKGTNEHNRKIWGEPKSIQDIANLFVGYMSGKVESLPWSEAPINEEANTLVD
DLVQLNSRGLLTINSQPAVDGVKSSHPTYGWGPRNGYVYQKQYLEVLVSPALIETVIARM
NSDPEITYYAVNCNGELKTNAPPDGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYH
LGLEWSKCYEEGSESRKIIREVTQNWYLVNIVHNDFRQQQGIFPIFDGLKAPGLEPAEVN
GVNGHAETNGVAPETNGVPDGNNAVNGADKVASSNSAQTA
>A0A375CYZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus taiwanensis|TrEMBL
MRAAPTRRATIMQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQ
GTLDAVLEIQREGIEAAPHLSCVGSSRESIRAILQQYREGGIRHIVALRGDMPSGMGEIG
EFRYANELVEFIRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVKAGADSAITQYF
YNADAYFRFVDDVRAQGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDD
RESIRAFGLDVVTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A0H1R7Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga vignae|TrEMBL
MSPMTLRPSRQASSPIKVSFEFFPPKTPEMETTLWASIQRLAPLNPQFVSVTYGAGGSTR
ERTHATVSRIVTETHLKPAAHLTCVAATTEEVDGVIRSYWDAGVRHIVALRGDPFAGIGT
AYEPHPGGYRQTCDLVAGIKAIGDFEVSVSAYPEKHPEAASLDSDIDVLKAKVDCGADRA
ITQFFFDNDHYFRYLDRVRARGIDIPIVPGIVPVQNFKQTANFAAKTGASIPDWLAARFE
GLDNDVETRKLVAAAVAAEQVIDLVDRGVNEFHFYTMNRADLVYAICHLLGLRDQSVKVA
A
>A0A426RQR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingorhabdus wooponensis|TrEMBL
MILPLAQMQEASRAIASPLFAGLPGDCEISFEFFPPKTEKMEEQLWDSVVTLSPLGPRFV
SVTYGAGGTTRERTHNTVARIARETQIPAAAHLTCVEASKSEIADVANAYWEAGVRHIVA
LRGDAPNSDGKFVPHPDGYASAAELVEGLRKLHPFEISVSAYPETHPEALSAASDIDFLK
RKLDAGASRAITQFFFEPETFFRFRDAVAAAGIDAEIVPGIMPVSNFAAITRMSHLTGTA
IPDWMADVFNGLDDHPSARQLVAATVSAEMCRKLYAGGVREFHFYTLNRAELSYAICHLL
GKRPTALAQKAAA
>A0A5T0PY02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKPKAAIKIYEAVKHLLKEELHA
>A0A381CQS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLIKEELHA
>A0A690MTC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHTILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALADIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A7Y5RXU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MRIRELLATGRPSFSFEFFPPKTAQGQVQLLDAVLALRELKPTYVSVTYGAGGGTRDLTV
DLVSRIKRDHGIETMAHLTCVGSSRDELSAILDRLSTAGIENVLALRGDPPRGQTHFTPA
PGGFSYASDLTSFIRAAYRFCVAGACYPEKHVECPTMEQDLVHLKRKVDAGAEFLITQLF
FDNQKYFNFVAEVRAMGIAAPIIPGIMPITNVDQIERFTRMCGATIPEPLLSELDRLRDR
PDAVLSLGVAHATAQCLELLQKGAPGIHFYTLNKSAATRTILTALRTVWPPARQPA
>A0A494VSM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter celer|TrEMBL
MKIPEHIVNANGKTLFSFELIPPLKGQSIQGIYDAIDPLMEFKPPFIDVTTLREDFIYKQ
HPSGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENALIELEFLGIEN
VLVLRGDARLGDSSFVPTPNGHCYATELLQQVVNLNNGIYLHEDHGNTAKTNFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGAQFIVTQMFFDIEKYKEFVNGCRANGITVPIIPGLK
PITSSKQLVTLSKTFHIDLPEDLTDAIHACANEKAVKEVGIEWMINQCKELMAFGAPVLH
FYTMSNAGPTKRIAEAIF
>A0A1B1ZTV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. HH130630-07|TrEMBL
MASDGTTATDDLLARTRDGVLLYGLTPPRASSTPEQADAVAAAALARLRDVRVDGLVLYD
VDAEADRSATPRPFPFLPMMDPAVFLDRHLTGWAGPVVVYRAVGKYAPDELDRWFTRTDD
GRVLTVLVGAASRHQAVRTSLPEAHRRHAAAVRAPRMGGVVIAERHAGAGTEHERMRRKQ
DAGCEFFVSQVCYDLDHTRNLLSDYVYGCRDQGVDPRPVVLTVAPCGSVKTLEFMSWLGI
DVPGWLRAEITRSPDPLAASYEQCLVNARVLIAFCRRLGLPFGINVESLTNRKVEIDASV
DLAGEIRALLG
>A0A162K3T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akanthomyces lecanii RCEF 1005|TrEMBL
MEKITDKIAALPADGEYFSLEFFPPKTAMGFSNLRDRLHRMEQGLRPLFVNVTWGAGGST
ADKSLELAELCQRELGMTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKEE
YRTAEDEEEDNEAGEDFVWAIDLVKYIRKKHDDYFCVGVAAYPEGHADESHPLGQSLEHD
LPYLVDKVQAGADFIMTQLFFDIDAYEKFEATLRQHPSGAFKTIPIMPGLMPIQSFAMIK
RTAKLSHAAMPPAILERLTAVKGDDERVKAIGVDILSELVEQVRTVKSKTPGPKGFHFYT
LNLEKAVTFILERTNLIPDEPAAEEAIVDGGPTSAPFLQVNGHAIPRPRSHSRSSRRHSS
VGSDPHNRVIASSGRRTNPEWEATGAEAGALAEPLNSRANTLAISEGEGALGREATWDDF
PNGRFGDSRSPAYGEIDGYGVSLHMSVTQAVRLWGHPATKQDIDDMFVRHVRGELAALPW
SEEELLAESSTITPHLAALNAKGWWTVASQPAVNSTRSSDATFGWGPANGFVFQKAFLEF
FLSSADWAALKEKLQRPGVREVVCFYAANAKGDFVSSDNASSATAAATTTTSSTNAVTWG
VFPGKEIVTPTIIEEVSFRAWCEEAFGIWDEWSRVYGKGSPSATLLGGIRDDYWLVNVIH
HDFVDQQALWDLLLA
>Q8PP97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis pv. citri (strain 306)|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A3B6LW64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Triticum aestivum|TrEMBL
MKVIEKIQEAAANGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPNFCDITWGAGGSTA
DVTLDIANRMQNMVCVETMMHLTCTNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFSCALDLVEHIKAKYGDYFGITVAGYPEAHPEVILGEEGATEEAYSKDLAYLK
RKVDAGADVIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNL
GLIEESKLSRTLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWGDSRNP
SYGALNDHQFTRPRGRGKKLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPE
TTIIDDQLVKINSKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYVEFFCAKEKLG
QLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWSRGWACLFPEGDSSRELLEQIQKSYYLVSLVDNDYISGDLFAAFKEI
>A0A168JZR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akanthomyces lecanii RCEF 1005|TrEMBL
MHVKDLLAETKRSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPQFIDITWGAGGRVA
ELTCEMVLQAQAVYGLETCMHLTCTDMGMEKVNDALHKAYKAGCTNILALRGDPPRAQEK
WTATEDGFQYACDLVRHIRATYGDHFDIGVAGYPEGCDDNDNEDELIEHLKYKVDLGGTF
IVTQMFYDVDNFIRWVGKVRAAGIDVPILPGIMPIATYASFLRRCKHTGCNIPQGWLDLL
EPVKNDDVAVREVGKKLVVEMCRKLMAAGIHHMHFYTMNLAQATRMVLEELSWTPSAERP
LQQALPWKPSKGFGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRLKWGEPKSLRDIANTFVRYLNQEIDSLPWSEAPLTSEADSIKPALME
LNQRGFLTINSQPAVDGVKSSHPVHGWGPANGYVYQKGYIELLVPPEIVDQVIHLVNANP
SLTYYAVTKDGNLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFEANSPSRVLVEDVMDNWYLLNIVNNDFHDNTTIFELFKELQVEGLDTPMTVKAEAS
AAAAAEKPTAVQAEVAA
>A0A7X7WTQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MSLQEALESGKFVVTAEIAPPKGTNTDEIKHLLDLYDGRVDAINATDNQSAVMRMSSLAL
SKIVLDHGHEAVVQMTCRDRNRLALQSDLLGAHALGIRNVVAMTGDHVIAGDHKQAKPVY
DVESVQLLQMIRSLNEGRDMMGTPLKGPTGFYAGAVVTPEANPLEPQLIKFAKKVQAGAK
YFQTQAIYDITMFNIFMSHARKMGAKVLAGIVVLKNERMAQYLNDNIAGIRVPAGMIAEL
AAAPSKAEKLETGIRMAARLIRQLKEERICDGIHIMAIGMEERVPEIMKQAGLLSD
>A0A8C3G8C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclopterus lumpus|TrEMBL
MVNQVQRGDGSLRSCKSDSSGLSNSGGESSKESSRCSTPVLEADRSDRLRDKMRRRTESG
DRWFSLEFFPPRTASGAVNLISRFDRMSAGGPLFIDITWHPAGDPGSDKETSSMMIASTA
INYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEEGFNYAT
DLVKHIRSEFEDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITRVIEPIKDNDAAIRN
YGVQQAVEMCRVLLDSGKVPGLHFYTLNREVAIMEVLRQLGLWIEDPRRSLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSTKDA
LLQMWGAELMNEESVYEVFTCYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNK
RGVLTINSQPNINGKPSADPIAGWGPAGGYVFQKAYLEFFTSSENVTALLEVLKKYEPRV
NYHIVNVHWNHSDLKK
>A0A1I3H258|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. UNC496MF|TrEMBL
MKPDLREALKARILTGDGAMGTYLYGMGFPVGVSYEEFNLLRPEVIADVHRRYYGAGARI
IETNTFSANLMSLTNYGLDAEVEAINRAGVRIAREAVGGDAYVVGAVGSIRAGKRKNIST
LDLEGLFRQQIGAQLAEGVDGILLETFYDLEEALLALRIVRERSDLPVICQFAVEKEAVT
LDGKPIAAAFESLRLEGADVVGFNCRSGPNGILRAIDSIGGEPGLPLSVFPNAGIPDYVD
GKYQYTSTPDYFAESARKFADRGARIIGGCCGTTPEHIAAIAAALDGYAPRPVDPADRLA
AAPAERLTVREPKQPEERAAKTEPTIVDLVNRRHTVIVELDPPRDLDIRKFMDGAKALKA
AGADAVTMADNSLAVTRMSNIALASLVQHQIGIKPLVHIACRDRNLIGTQSHMMGLDALG
IDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGVAFSGKTLKQKASFVTGAA
FNPNVKYLDKAVARLERKIETGADYIMTQPVYDKALIARIAEATRHLNVPIFIGVMPLAS
GRNAEYLHNEVPGIQLSDDVRGRMAGLEGEAGRAEGVRIAEELLDAATDHFKGIYLITPF
MFYEMTVKLTDYVWRKTGSLAR
>R5T660|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:75|TrEMBL
MLYQGNIRDYLSKQPLLFDGAMGTYLADKYIQFGGESCEKWNLRYPERIKQIHKEYIDAG
AVAIKTNTFAANAGDHFTAEEVGKVIAAGTQIAREAIEESAGEQILFGDIGPVLIGDEND
AAERYRLPVDCFLEQGVRHFLFETLDNIEGLDEITEYIKQKQPEAFIIVSFAVSPEGLTR
SGCYGRSLYQKMMNVSSIDALGFNCISGPKHLLDLMYKLSREKNTKYISIMPNAGYPAVL
DNRTYYEAHHYYYAKEMYQIAKQGASIIGGCCGTDPSFISEIAKTLQQSPLPGRKTYSAD
GSGRSVHSVVENRQTEQSIPVANDGQEVKNYAGKDNLRNTFAAKLACGEKVLVVELDPPV
TPEIDFFMEGAAKYQQAGVDAIDIADCPVAKARIDSSILACKVMRELGLTAIPHMTCRDR
NINATKALLLGLNVEGVNNVLTVTGDPVPAAERGLVKTMFSYNSAVLANHIRTLNEQIFQ
NNPFMISGALNVNAVNFDSQIIHAKRKISQGIDVLFTQPVLTERALNNLKRAREELDVKI
LGGIMPVVSYRNACFMNSEMAGIDVDPRIIEMYQDKDRAQGEELAEQISAQVAQEIAPYV
DGFYLITPFKRVELILRIIKQIRGLLDR
>A0A4P9VYJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blyttiomyces helicus|TrEMBL
SFEYFPPKTETGVTNLYDRMERMYALGPEFIDVTWNAGGHSSDVTMQVRFDTGGGDGSGT
IEGGKAGLLHRAVRLRPRNVHAPVSLDT
>A0A356R143|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MHISEVLRTHNPAISFEFFPPKTERGFQELFEAISALMPLKPAYVSVTYGAGGSTRERTH
DLVVKLQRETDLTIVSHLTCVGSRRDEIHHILSKYQESGIHNIMALRGDPPKGRTDVQIP
EDGFHFASDLVCFIKQQFPEMGVGVAGFPEGHPGTPNRLQEMDNLRRKVDAGADYICTQL
FFDNRDFFDFCERCEVVGIKVPIIAGIMPIISRKGMARMSELALGARIPAKLLRAMDRAE
NDDYAERVGIHWATEQVVDLVDQKVKGIHFYTLNKSKATLKIYESLGIQSSESLQHSVD
>J2FUQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. AP07|TrEMBL
MTAPVPRRVIGPVARAGERTDRPRVSFEFFPPKTEQMEENLWAAINRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILEETSLKPAAHLTCVGASRAEVDEVIREYWETGVRHVVSLRGD
PPPGEGGIGGVYVPREDGYKNATELTSALTSIAPFNVLVGVYPEKHPESPSIAHDIEVLK
AKVDAGATLGISQFFFDTDAFLRFVDQVRKAGITIPIVPGIMPVTNFKGLVKMSKACGTA
VPGWLANLFDGLDEDADTRRLIACSVAAEMCAKLQEQGFSDFHFYTLNRADLVYAICRVL
GVREAAPTSSEAAA
>A0A0D3BPQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica oleracea var. oleracea|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRANGIQNVLALRGDPPHGHDK
FVKVEGGLGCALDLVNHVRGKYGDYFGITVAGYPEAHPDVIGENGLASDEAYQSDLEYLK
RKVDAGADLIVTQLFYDTDVFLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEVMAALEPIQDNEEAVKAYGIHLGTEMCRKILAHGTKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALTDHQFSRPRSRDKKLQQEWAVPLKSVEDIQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLVKINSKGFLTINSQPSVNAERSDSSTVGWGGPGGYVYQKAYLEFFCSKEKLD
AVVEKCKALPSITYIAVNKGENWVSNTAQSDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFETWSRSWADLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIFSVFADL
>A0A089YWF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces glaucescens|TrEMBL
MALGTASTRSDHAPTVRDMLATGKTTYSFEFYAPKTPKGERMLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPRGLTYAAELVELIKDSGDFCVGVAAFPAMHPRSTDWDSDVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDRVAAAGCDTPIIPEVMPIGSVKTLERIPSLTNAAF
PAVLKERILTAKDDPAAVRSIGIDFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A354A1D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MSFREILDSGKFTVTAEIGPPKGTDIKEMYHHIEVLKGKIDVANVTDNQSAVMRISSLAV
CKIVLDNGMEPILQMTCRDRNRIGLQADLLGASVLGIHNVLCLTGDHVHAGDHKQAKSVY
DVESVQLLKIVEGMNSGRDMSGNEMKGATDFYAGAVVTPEANPLEPQLVKFEKKVKAGAK
FFQTQAIYDMEKFKNFMAYARKFPVKMLAGIVVLKSAGMANFMNKNVPGITVPQELIEEL
KAAGKEKALDTGIDIAARHIRQLNDEKICDGVHIMAIGMEDKVPMIMERAGLR
>A0A0Q2MEY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio furnissii|TrEMBL
MGYTHASHIDALNQNIADLSDINVSFEFFPPSTAQMEETLWNSVHRLKTLKPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDASREELIQIADDYWHNGIQNIVALRGDI
PPGGGKPDMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLRRKVDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPSWMAKQFDG
LDDDPVTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPSL
>A0A258QDE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. 35-46-207|TrEMBL
MELSVEFFPPKTPEGESKLHVVRERFSETLKPAFYSVTFGAG
>A0A8C9W7N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scleropages formosus|TrEMBL
LIKVTALTLQCHDDCVRGNIPRPNLTFTLCFLKTMVNQVQRMDGGSQAPKSDSSGASNSG
GESSKESSRCSTPLLDADRADRLREKMKRRIESGDRWFSLEFFPPRTSSGAVNLISRFDR
MGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKDQITAHL
AKAKRLGLKNIMALRGDPLADVWEEEECGFNYATDLVKHIRWEFGDYFDICVAGYPTGHP
EAESYEADLKYLKEKVDAGADFVITQLFFRAETFLKFVKDCRAVGITCPILPGIFPIQGY
QSLRQLVKLSKLEVPEAMMQVIEPIKDNDAAIRNYGIQQAVDMCKVLLQSGDVPGLHFYT
LNREVATMEVLKQLGLWNEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQEWD
EFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALVKMWGEELMSEESVFEVFTNYITTQ
PNRNGHKVMCLPWNDDPLAPETNLLKGELEKVNRRGVLTINSQPNINGKPSSDPIVGWGP
PGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVQGKNITNAPEMQPNAVTWG
IFPGREIVQPTVVDPVSFMYWKDEAFGLWIEQWAKLYEDESPSRMIIQYIHDNYYLVNLV
DNDFPLENCLWQVIDDMFDLLDAPPVTVE
>A0A6N0HPW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Ruthia endofausta|TrEMBL
MKISFEFFPPRTNQGKEKLTQVRQSLSVISPEYFSTTFGAGGTTQNATLKAVLDIQKNGN
IPAAPHLSCIGSEKSNIVELLDKYKSANINRIIALRGDIPSDMHDIGDFHYANELVEFIQ
SEYNDYFHIQVAAYPEMHPQANNIASDLAHFVNKIKAGANGATTQYFYNADAYFRFRDDV
QKLGVDIPITPGIMPIINYTQLLNFSNMCGAQIPKWILERLKLYETDLESLGDFGFDVVS
NLCQTLKSQGVGSFHFYSMNRTEPSLKLAKSIV
>A0A7X3MC81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. Nvir|TrEMBL
MSFFHTSQREKFNQHFSDLNGEINVSFEFFPPRTSEMEEALWYSIERLSSLKPRFVSVTY
GANSGERSRTHSIIADIKKRTGMEAAPHLTCIDASYAELRTVAELYWNSGIRHIVALRGD
LPTGISKPEMYACDLVSLLKTVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATSIDVEIVPGILPVSNFRQLKCFANMTNIRVPGWMHAMFE
GLDDDPETRKIIGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTIGVRPVLAA
>A0A4U1JBC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polyangium fumosum|TrEMBL
MSSAPSALTPKPTRFLDAVRRGVLVVDGGMGTQIYERGVLFNVNYEELVVSRPELVLRIH
EDYVRAGAQVVETNTFGANRVRLARHGYADRVREFNVGAAQLARKAVGDRGYVAGAIGPS
GLVFAAFGEDDRSRVRDAFGEQAEALAEGGADVLLLETMRQPEEFLLAIDGVRRAVGDAL
PIVANVSVDADLTLSDGTPVADMGARLRDLGCNVIGVNCSDGPQVVLAAIEKLLPLDIPL
SAIPNAGLPRRVDDRFIYVSTPEYFGVFARRLCKLGVRLIGGCCGTTPEHIRRMAAAARM
EASAAAGACEDPGPLWVGVADSSIPPEPPVLVIGQRPVATAEKSKLAAKIGKKFVVSVEV
NPPVGVDPNSAIQAAKMLVTGGVDVINIADGARAQARMSNLALAVRMQEELGVETLLHVC
GRDRNLLGQVAHLLGAHALGIRNLVVVTGDPPKMGDFPDATAVYDLDSVGILRLASRLNA
GIDPGGKPLGGVTSFFCATGAEPAALNYEREMERLKLKKRAGAELIMTQPVYDPSVLDRF
LKDAEPLGLPVLVGILPLASHKNAEFLHNEVPGMQIPREVRDRMQRAGSGPAARKEGVAI
AREMLAAVRNRVAGAYIMPPLGRYELALEVMDGIV
>A0A7C7IM62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesonia sp|TrEMBL
MKVVDHIKKAAGKTLFSFEILPPLKGQNIQSIFDHIDPLMEFEPPFIDVTYHREEYVYKE
LSGGLLQKKVVRKRPGTVGICAAIQNKYEVDAVPHILCGGFTKEDTENFLIDLDFLGIDN
VLALRGDAVKNETYFSAEKEGHTYAKDLVKQIVGLNKGEYLDEELLNKSKTNFCIGVAGY
PEKHMEAPSLDQDVLRLKEKVDAGACYVVTQMFFDNQKYFEFVDKCRKAGITVPIIPGLK
PLATKKQLSILPHRFHVDLPDELTLEVLKCKSKEEVRQVGVEWCIQQSKELIKGSVPVLH
YYSMGKSDNIQKIAGELF
>A0A7M2YA93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kaistella flava|TrEMBL
MKITDHLKNANGKRLFSIEIIPPTKGTGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERKITRMRPGTLGICAAIQHKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGIEN
VMALRGDAMKGQQYFEPTIGGHKNATDLVCQMNDLGRGKYLHDENFSDENNKFCIGVAGY
PEKHIEAPSMNYDLKWLKQKVDAGADYVVTQMFFDNEKFIDFVKSAREIGINVPIIPGIK
PVATKKQLQLLPQVFKIDLPEDLISAIENAKDNAAVKQIGIEWTINQCRELLNFGVPVLH
FYSMGKSDNIKKIARELF
>A0A7V4DHH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Caldatribacterium californiense|TrEMBL
MSVLRELLERGVFVVTAEVGPPKGVDRESIVKKCAQIRGFVDAVNITDNQTAIVRLSSFA
SCLIVREAGLEPVMQLTCRDRNRIALQSDFLGACALGIENFLCLTGDHQSLGNHPEARSV
FDIDSVQLLDMFRRIRDEGVFANGEKVKGEVRAFLGAGENPFADPLEFRVFRLAKKVEAG
AQFIQTQAVFDLELFSRWMEEVRRLKLHEKVHILAGVIPLKSLQALRYMKDEVPGMVIPA
WVEERMQNARDPKEEGVRIAVETIAALRAIEGVRGVHIMAVAWESIVPEIVRASGLFPRP
GQGGGEGV
>A0A8J5YTE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium anomalum|TrEMBL
MKVIDKIQSLSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DALVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSQNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A7G8UFJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. PAMC21692|TrEMBL
MSGALAAKLSLREALAERILTGDGAIGTYLYQMGFPVGVSYEEFNVLKPDVIENVHRQYY
EAGARVIETNTFSANSVKLSKYGLESEMEAINRAGVRIARAAVGPDAYVVGAVGSIRDGK
LKNLRTSLVADAYEQQMKALLEEGVDGLLLETFYDLAEMKLAMSIARKLTDVAVICQFAV
EDVGRTLDGVALSDAFRELKEMGADVIGFNCRSGPNGIMRAIDSIGERPENLPMSVYPNA
GIPDYVDGKYAYSAGPEYFAESAKRFADRGARIIGGCCGTTPEHVAAMAAALAGYVPAAP
GANQAESAAISVTETLAGGTGEGDRDETPNIVDLVKQRHTVIVELDPPRDLDISKFMTGA
AALKEIKADAITMADNSLAVTRMSNLALAALLKERVDIRPLVHIACRDRNLIGTQSHMMG
LDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNDGIAFSGKPLKQRAKF
VVGAAFNPNVKHLDKAVQRLERKIASGADYIMTQPVYDPELIARIAESTKHLEVPVFIGI
MPLANGRNAEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAEGVRIAKELLDAVLPHFNGIY
LITPFMFYDMAVQLTEYVWQNTKQLS
>A0A379BDG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella multocida|TrEMBL
MPGILPVTNFKQLVKMAAITNVKIPAWLAKNYEGLDDDPTTRNLVAASVAMDMVRVLSRE
GVNDFHFYTLNRSELTYAICHTLGIRPSIE
>G2PGL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces violaceusniger (strain Tu 4113)|TrEMBL
MNPPSSVRTAVGTSLLEDFSLEMTGKDVPELEEARDTIPQGTRINITFLGNEDLRMRLDA
AREVKRLGFVPVPHISARRLGSRDDFERFLAGLHADGTSDNVFVVGGDPARPEGPYADSL
SLIGTGLLQEYGVRHVGISGYPEGHPAIDADALWSALRDKHAALADQPLEGCIITQFGFA
VDPVLAWVEEVRRRGIDLPIRIGVPGPAGVRRLLSYAARFGVGTSASVVRKYGFSLTNLM
GTAGPDRFLRDLTAAHDPGHHGELKIHFYTFGGLGATSDWAARIRKESPA
>A0A1G8JDL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. Rc2d|TrEMBL
MTDVTTPGKANGQDGHLKRPAISFEFFPPKTEEMERNLWDTINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPVG
GIGTPYFSHPDGYQSSAELVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARAFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A292GM77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. PY1|TrEMBL
MTTPIIHPNWARPALNMVDGYSLEITAKDVDSLRAAAPGILPETPIALTFLPGEEFDARV
AAARTVRELGFEPMPHFSARRITSRDEFERYLAAVTREAGVKRSFIIAGDPAEPEGPFAD
SMALIATGDFERNGITAIGIGGHPEGHPNMSDEQCWQVLEDKCNAIVARGMAPLIVTQFA
FDADAVLAWLKKLRERGIEAPVRLGVPGPAGIKTLMRFAARCGVGASATVMAKYGISITR
LIGSAGPDKLVKSLEQGLGEEHGPVRLHFYPFGGLEKTVAWINEFARKN
>A0A0D0GL45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter lusitanus|TrEMBL
MKITNHIDNARGKTLFSFELLPPVKGKSITDIYDAIDPLMEFNPPFIDVTYHREDYIYKQ
HDNGLLEKVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADSTFIPTPGGHAYATDLLGQVNDMNNGKYLFEDHSAFQTDFCIGVAGYP
EKHFEAPNLKTDFKYLKQKVDMGAEFIVTQMFFDNAKYCDFVAQCRANGINVPIIPGLKP
ITSSKQLISLPKIFHIDLPEDLTEAVQECKNEKDVKEVGIEWMIQQCKELIKFGAPVLHF
YTMSNPEPTKRIARAVF
>A0A3E1RA23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax lacus|TrEMBL
MSNAKRVPLSLEFFPAKNPDVAAKMVGIRKDLSVLQPEFCSVTFGAGGTTQEGTFATLRE
MVAEGTAAASHLSCIGATKASIAEQLAQLKAMGVKRIVALRGDLPSGYGVGGDFKFGSDL
VRFIREETGDYFSVEVAAYPEVHPQAKSPAADLEAFATKAHAGANSAITQYFFNADAYFR
FRDDVVAMGVEIPIIPGIMPITNSTQLMRFSDSCGTEIPRWIRLRLQSFGEDTASIKAFG
MEVVTDLCERLLKGGAPALHFYTMNQSAPVLALCSCLGLTPVAQPRVLQAAA
>A0A7K0J7P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium porci|TrEMBL
MQSQKPTIADLLASGERPLHSFEFMPPRSEDDVYRLWSATDALVPMAPDFISVTYGANGS
RRDRTLRCTQHMVSTGLRTVGHLTCVSQSVADLEQMVADYAESGVDHILAIRGDMPGGAR
QPWEPHPDGLPNATELVRLVKRIHPDACVGVGAFPDGHPEARDIDVDARILVNKAEAGAS
FAITQLFFFPSHYQRLVAKVRDMGCDIPIIPGIMPITSYGQIRRFAELSGTDVPAELVAQ
IEEVKDDKAAVRRIGLAAAVDMCCELLDAGAPGLHYFTLNRSRATTELRTMLAQRRPDLA
GLPHGAQASSAA
>A0A4R2NLU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum adriaticum|TrEMBL
MSAPRVSFEFFPPQSLEASFRLWETVQALAPLKPGFVSVTYGAGGTTRKLTHDAVETIHK
HYGLNVAAHLTCVEATRAETMEIVESYAEAGVTEIVALRGDPPKGHGSFTPHPDGFANSC
ELVAALAETGKFKIRVGAYPDPHPESKGPGSDVRWLKKKFEAGASSAITQFFFEAETFFR
FRDECEAEGIDGSKIIPGILPIEKWAGVRRFAERCGAHIPTWVDDAFEKAQRDGREALLG
QAMATELCSQLMDGGVRDFHFYTLNKPHLTRDICHALGVQPEGHLEKVA
>A0A8B9PW26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apteryx owenii|TrEMBL
MVVLAQTSLPFYLQSSAAHPSTYCSLVRSVFSLIPTVLLFLSTREFTMVNETQHTCSASS
SSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDKWFSLEFFPPRTAS
GAVNLTSRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVNYCGLETILHMTCC
NQTKDEITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVEGFNYAVDLVKHIRNEFDDYFD
ICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLKFMKDCQAIGITCP
IVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLD
SGMVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRP
KSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESV
FEVFTCYITGEPNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNINGK
PSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNYHIVNVKGQNITNA
PDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKLYEEESPSRMIIQY
IHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A735AQS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Rough O:-:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A838YTC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emticicia sp. BO119|TrEMBL
MAKVTEHLSNTQGKPVFSIEIIPPVKGSNIDDLLKSIEPMMELKPPFIDVTFHREEYILK
NLPDGGTKEIKIRKRPGTVGICASILHKFGIDPVPHVLCGGFTKEETEDLLIDLNYLGIE
NVLALRGDYARPYNSFKARKDGHFYANELVSQINNMNNGKYLHEEAEYLNASDFCIGVAA
YPEKHFEAPDLDQDIENLKRKIAAGADYVVTQMFFDNQKYFDFVNRCRAEGITIPIIPGL
KVLATKKQLDVLPKLFYLDMPEAFRKEVTACENDKHAKQLGIEWCVQQCRELMDFGVPAL
HFYTMSKSDTTLAVARQIF
>A0A524MPI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerales bacterium|TrEMBL
MSRLKESMCEAGAFVVTCECVPGRGPRGKSIDEIVEFAREAVSTRLPIHAISTTCNPGGN
PAISPDILGVELEEVGIETLIHFSCANANRNTIEARATALARNGMQNLLVVSGDYPVGGY
QGMAKPVYDLDSVQTLRYLKDMNNGLHVPGRKPATFDTLPQTEFFLGCAVSPFKLTESEL
MPQFFKLEKKIQAGADFIIPQLGYDVRKFAEILKYMKYRGIGVPLIGSVYTLSRPVARFM
NKGMIHGCIVTDELLKKIEDEAEAPDKGRAARIERSAQLMAIFKGLKFQGVHIGGFGLKC
ADYANIISRSQEIGDNWRDYVENFGYNRKDEFYLFPEDPDLTFDEDKLVPVESAHRPRKP
VHFMMSLLVHRLVFKEDTLGYRMTQGLYRLISKSSILSRIAYFFERQIKSLLFECQECGD
CALFDLAYLCPMSQCAKFQRNGPCGGSTNGMCEADEKKKCVWPKVYARYAAIRKLDKIRL
DYVPPVDCSLAKTSSWENFFLGRDHTAKKLQALREAKKN
>A0A1D8GEL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geosporobacter ferrireducens|TrEMBL
MSTEKLSFRDALYEPEKFAVVWELVPGRGAWEQSQDQVLKMAELAAKDSRINGITITDNP
SGKPAILPYPLAMEAKKLGIETLIHFTCKDKNRNDIESELHALARSELKNLLVMTGDYTT
EGFSGRPKPVFDLDAVHTLRMIEKMNQGLEIHGHKGKIKLQATEFFGGAVVSPFKLKEGE
VMAQYYKLHKKIANGAKFIITQLGYDARKFDELRKYMDLNNFNIPLLGNIFVLSLPVAKL
MNKNKIPGCVVTDEMMFPLHNEKQKYGNSKEPQLLRAAKLYALLKGLKYDGVTIAGHGLE
YSDIQYILDKGEELAPNWMELIAEFNYPQRDGFYFFEKDETTELNTNNPVDRTKTGSAKS
SILDAMFHMVHKVGFNQKSSLFPVIRTTARVIDKTFLKKPFTYFEYMTKTITNECCFCGD
CAMHELAFQCPMSQCAKQQRNGACGGSRDGWCEVYPEKQKCIYVTMYEKFKAAGKEESMK
KGYIPPCNWDLYRTSSWLNYFNDRDYNSKTKENE
>A0A177E6L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfatator autotrophicus|TrEMBL
MSEDKKYLSHLERVLKEGHFAVTCEIGPPKSADPEVVRKKARIIRGFVDAANITDCQTAI
VRMSSIASGVLVREEGVEPVIQMTCRDRNRIGIQADLLGAAALGMRNLLCLTGDHPKFGN
HPEAKGVFDLDSIQLLDMVRRMRDEKKFQCGEEIKGKAPEFFLGAAENPFADPFEFRVHR
MAKKMAAGAQFIQTQIIYNLERFRKFMEMARDLGLTEKLFILAGVTPPKSFGMARYMKYF
VPGLDVPDEILTRLKDAKDKKEEGINIAVEIIEQVREIPGVAGVHIMAIEWEEAVPEIVK
RAGLEKRPLAEEVKPVVKEERVPEVVITEEKPEVVPEPEAPPKVEVPVEALKNVFSSLRS
SMEALRDGINMLHEGLANLEKTLLGGEVPPPPPSEEKRPPVEEVPREPKPEAPAIPKEEE
EKAKQVADLLSAAKAAQESGDYEKALNLYEQVLSLEPENELAKNAIEALKKEQKIAELLK
IAKEKLEAKELDEAEKLFKEVLEISPEQEEGRAGLARVEELKAEEKPPVVEEKPEEKPEV
KAETPEVSEILVFSDLSSDYRDVSERAAGIPEDVYKEPGSAWIKEVTIGEGDKKITFGGT
NVLPFHLFEGEMKNPPRVAMEVLDVKPEDWPEAIAKYFEDVFDDPGEWAKKCVEVYGAEA
INIYLVGTDPNFLNLGPDHAAKVVEKVAKAVDVPLVIWGSGSPEKDVDVIREVANVLGAK
NVMVGPVVDTNHRALGATAMGYGYALIASSPIDVNLAKQLNILLENVGVPLDRIGMDPSV
GAVGYGLEYTYSVMERIRLAALYAGDDKLQVPFVINVGREVWKTKEAGLPSDEMLGEQEI
RGIALEAITAISLLMAGGDFLVMRHPKAIEVTHKIIKGLMAQE
>A0A3E1R7J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax lacus|TrEMBL
MKFDDEPVPGYPLPILPGHTSPGRLERVLRAGVFAVTAELDPPDSADPEDVYKRARIFDG
YVDAINATDGSGANCHMSSIAVCALLTRIGYAPVMQISCRDKNRIAIQGDILGGAAMGVA
NMLCLSGDGVQSGDHPQAKPVFDLDCMSLLNIGRTLRDEHKFQSGRKVTFAPRVFFGAAA
NPFVPPYEWRAERIAKKIAAGAQFLQTQYCYDVPRLKSFMQQMEDLGLLEGPNKAFFLIG
VGPLRTAKAADWMRTNVPGIHIPDDVVKRMAGAEKPAAEGRQICIDLIQEIKDIKGVSGV
HVMAYRQEESVAEIIQKSGVLQGRVPWYPGRDIPTNTEKETT
>A0A0F5RUU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. UMTAT18|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIVSIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPDYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A5S4F0Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea turkmeniaca|TrEMBL
MALGRPSIRPDRVPTVREMLASGGRTFSFEFFPPKTDEGERQLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERIAHGTTLTPVAHFTAVNHSIRELRHLIGRFADAGVRNILAVR
GDPPGDPTGEWVQHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTEYFVS
KCRAGADYAITQMFFQAGDYLRLRDRVAARGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPDVAARFEEVADDPAAVRRLGIDHGAELCQRLLDEGAPGIHFITFNRSSATREVFQRLA
VPISA
>A0A643FET1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ideonella dechloratans|TrEMBL
MTPDFPLSLEFFPPKTPEGAEKLAAARQQLYALDPTFCSVTYGAGGSTQDGTLQTVQAIL
AEGRDSASHFTCVGATRDSVREKLAQFKAMGLRRLVALRGDLPSGYGSMGEFRYASELVA
FIRAETGDHFHLEVAAYPEMHPQARSPQADLQAFAAKVAAGASSAITQFFFNADAYFRFV
DEAHALGVNVPIVPGIMPITNASGILRFADSCGADIPRWIRLRLQSFGDDSASIKAFGLE
VVGALCERLRAGGAPGLHFYTMNQSGPTLTLCRQLGLVA
>A0A254RUT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWB5|TrEMBL
MKIVDILKQDKMSLSFEVFPPKKETSFESVKAATESIAALGPAFMSVTYGAGGGVSHFTL
DIAKNLKQKFGIPMLAHLTCVSSSKETVHQRIEDMKAAGIKNVMALRGDLTPELIEKGRD
NCDYHYAVELIRELKASDADFCIGAACYPEKHPESANQAEDIKHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGILKNVTAILGKNFAG
>A0A1T2B9S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioclava sp. DLFJ5-1|TrEMBL
MTTPKVSFEFFPPKTLDASFRLWETAQVLAPLKPEFTSVTYGAGGTTRKLTHEAVGTIHK
NYGLNVAAHLTCVEATKAETMEIVDAYAEVGVTEIVALRGDPPQGAKHFTPHPEGFASSV
ELIEALAEDGRFTIRAGAYPEPHPDAADAMADVRWLKRKVEAGATSAITQFFFEPETFFR
FRDACEKEGIDAKIIPGILPIQSWKGAKKFAQSCGTSIPAWVEEAFEAAIRDGREHLLAT
ALCTELCDKLIEGGVEDLHFYTLNRPGLTRDVCHALGVTPDTVLEKVA
>A0A259I2R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium 39-62-4|TrEMBL
MATPQIHPNWDKVPDGITDGFSLEMTAKDEASLRDAAPLIPAETPIAITFLPGEDVAARV
AATVAVRELGFEPMPHFSARRITSEDDFEGYLRAVVQKAGVERCFIVAGDPPEPVGPYFD
TSALIATGAFERSGIKAIGIGGHPEGHPNMSEAECWAVLEKKVADITARGMAPLIVTQFG
FDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVTN
LLGTAGPDKLVDAFAKGLTAEHGKVRLHFYPFGGLTKTLEWLHGYNKKHGIGA
>A0A1E8GQ31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Floricoccus tropicus|TrEMBL
MNKIPFSLEIIAPPINTPYENFKDDLEDFIELNPSFIGVPTIDKVNMNKRSFELTRYIQN
DLSYPAMTHLPAKFMNQKHVEDALNSFANSGVKEILVVGGEVRDEAKIYSDFPYANQLMS
FIREYSSDFHVTGACHPRGVEGDGDLAREMEDIKRKIDSGCQQLISQAFFDNEDFYRFKE
AYEKENFKIPVLAGVMPAFSRGVINFMVSRNHTRLSPELEKRLVKYANDPISFRQAGLEY
SMEQIDKLLGCEIDGLHLYTMNDVLASKELYMAFRN
>M9RMX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Octadecabacter arcticus 238|TrEMBL
MSRPSVSFEFFPPKSLQASFRLWDCVQTLAPLDPSFVSVTYGAGGTTRQLTHDAVDAIVK
TTDLPVAAHLTCVDATRAETLEIAAGYKAAGVTHIVALRGDPPKGTGGFAPHADGFQSSI
ELTSALADEGFDVTVGAYPECHPDAASQQACINHLKAKIDAGATRAITQFFFESDTFLRF
RDACADAGITAPILPGILPIENWAGVQKFAAGCGTAIPQILKDAFGNATDPDVINLLATA
QATELCDELLTEGVNHLHFYTLNKPELTRDICHALGMEPALRLQNVA
>A0A1I2KQI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. CF458|TrEMBL
MMANHNFSIEFFPPKTAEGTEKLRVVRAKLSELHPKYFSVTFGAGGSTQQGTLDTVLEIM
EAGEQAAPHLSCIGGTRESIRAILQQYKAHGIKRLVALRGDLPSGYGMSGEFRYANELVE
FVRAETGDWFHIEVAAYPEVHPQARSPQDDMQAFVRKVNAGANAAITQYFYNADAYFHFV
DAAQKAGVNVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLD
VVSDLCERLLAGGAPGLHFYSMNQAVATTALWNRLV
>R9KST7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium MD335|TrEMBL
MKTAELFKKKTVLSYEVFPPKTTDDAHTIYEALDGLQGLCPDFISVTYGAGGGTNCAKTL
DIAAAVKNQYKIESVAHLRGLDLSRDEVLQIIGELNEKGIENVLALRGDAVQDTVPTGDF
KHADELIAYIRAHSDLNILAACYPEGHPECKSLAQDIAYLKRKADAGASQLITQFFLDNE
DFYGFLEKVRAAGITLPIQAGIMPVTNRKSIERMVKMCGIKLPKKFMRIMDRYEHSPAAL
RDAGIAYAIDQVIDLLAHDVDGIHLYIMNKPYTAKRIYEAVQNIISA
>A0A511YBU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium lathyri|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTPGGHASAMDLVHQINDLGRGKYLHNDEKACDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKEKVDAGADYIVTQMFFDNKRFIEFVTKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A6B3GDR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7982|TrEMBL
MALGIPSTRSDRAATIRDLLDSGGRSYSFEFMPPRTADAEVGLWRAIRRLESLSPTFVSV
TYGAGGSTRGRTVNVTGRIAQETTLTPVAHLTAVDHSVAELRNILGHYADQGVRNILALR
GDPPGDPLGPWTRHPQGVEYAADLVRLIKESGDFCVGVAAFP
>A0A264W1S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetzosporium hominis|TrEMBL
MKRPFLEQLRERVLVADGAMGTLLYSYGVDHCNEELNLSHPEDVLRVHEQYIEAGAEVIQ
TNTYAANYVKLARYGLQEQVKAINTAAVRLAKQAAGEDVYVLGTIGGLRGIKQDIPLDEI
KRSFREQLYIFLMEGVDALLLETYYDFEELETVVQIAKQECELPIIAELSMHEVGVLQNG
WSLAEGLARLEELGADVVGINCRMGPFHMLTALQQVPIPQKALLSVYPNASLPQLEEGRY
TYAEEFAYFGDIAQELRQQGVHLIGGCCGTTPGHIQAVAKRLTDRTPITEKQAIPHKAVR
KVMEPSGESPLLQKVRNETTILVELDPPKHLNTDRFYEGIEALHKAGADALTLADNPLAS
PRVGNDAVAAIIKQRYGANPLVHLTCRDRNLIGLQSHLMGLHELGVQDLLAITGDPAKIG
DFPGAASVYDLSSLELIELIKQNNKGFSFSGKSLERPTRFSVGAAFNPNYRHMDASIKRL
EKKVAAGADYFITQPVFGIEQLHALAEASKQVDRPFFVGIMPLLSSRNAEFLHHEVPGIR
LPDDTRERMRQAGEDPKRALEEGMAITKELVAEAVKLFNGIYLITPFLRYELSLELIHYI
TSRKQEESHDQLYI
>A0A5N5ENR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces arboris|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A356EM37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MVVPRASVQNDPKQTGIVMSEQAPLTFRDIIADERFHYGAEVVTTRGLNPADSPSSVVGL
AQDLLADPRIGWISVTDNPGGGPMLPPDWLAGRLSEHRRRMVLHLTCKDMNRSGIEAAAW
RYASEGFENILAITGDYPTGGFGGTAEPVFDLDSLGLIHLLHLMNEGLQVPGRRGSLEKL
PATNFFIGCVVSPFKRHERELMPQYFKLIRKIAAGAEWIVPQLGYDMRKFHEIKLLLASR
RLDVPVVGNVYVLSGFVAKLFHSGKLAGCVVSDELLETCQKQAASPDKGQKFFHEFAAKQ
LAVFKGLGFTAGYLGGLAKAETFGKVIDLAESFGENDWRDFLPEIRYSQPSEFFLFEHDR
KTGMSAPDRINPEYLRSMKRPPRSKHVTLNYRVSRMVHSLAFHRGHKLYGLMTRLFRXRL
EKDGKPNLLGRMSYWIEKHAKYVGYGCEDCGDCSLPDCVYLCPNSACSKSTRNGPCGGSL
DGRCELDDKDCLWARAYERLKHYGESEQLTEGLPIIHDAGLKHTSAWANTYLDRDHFAAI
AKQLAEDNVKKDTNKDEG
>A0A6N4ATQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Synechococcus spongiarum LMB bulk10E|TrEMBL
MKSQVSPSAFQQALASGQPVMTAEISPPRGGSVQHVLATADRLRGRVHALNVTDGSRAVM
GMSSVAVCRLLLERNLEPVLQVGCRDRNRIALQADLLGAHALGLRNVLCLTGDPVKAGDQ
PKARSVFDYEAVRLLRDVKNLNQGLDALEQLLPDGPTALFPGCAADPQSPSWSGLKGRLQ
RKKEAGARFIQTQMVTDLAALRRFCRELATPLGLPVLAGVFLLKSGKNARFINRMVPGAS
IPDQAIARLDGARYPQAEGIRMAAEQVAAYLEVAQGVHIMAIKAESAIPQILDLAGVPPL
APPIVAGVDLKSLAAEPC
>A0A1P8PLK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter schindleri|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKIVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADNFDADIKRFCEKAHAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A3B8KUK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
EWISRVRDIGICNIMALRGDPPRGTDSFAAVSGGLEHANQLVDLIRSQGDRLGVGVAAYP
EVHPEAVNAAVDLENFKRKIDAGADAAFTQLFYINENFLRFRDRCQAEGISVPLIPGIMP
ITGYSRIQRIASLCGAQIPVELA
>A0A3R9FAX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis eburnea|TrEMBL
MTSVIERLRGDGPKFSIEFFPPRDAADEAVLWKAVRELEPYDPAYMSITYGAGGSSRDGT
VRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYASVGVRNILALRGDPPGDVYGEWI
PHPEGLTYAEELVQLVRELGDFCVGVSAYTYGHPRSPDLDTDTKYLVRKLRAGAHFAIAQ
LFHDPEDFLRLRDRVAATGCDVPVLPGVMPLTTMRTLQTTIKLSGAPAPRKLLDRLEPLA
DDPKAFRAAGIDVTTELCEKLIAEGVPNLHFYTFNRSKATREVIARLGLVPARA
>A0A6J4R4N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Solirubrobacteraceae bacterium|TrEMBL
ARGAHRRAAGQLRRALVLLRVLPTEERRGRAQARGGARRALAPGADVRVGHLRRGRDGEP
EAQDDRDRRPGEARPRPGGDGALHLRGGDRLGAALDARADAGDRHRQRPRAARRPASGRD
GLAGHRRRPDLLARADRAHPRRVRLRHRRRVLPGGPRPRQRRRERPALHEGEGRRGRSLP
DHPAVLRQRALLRLRRPRPRHGHRRPDHPGHHADHQLRAAAALHRPVRGGDPRRPARGAR
GPRRRSRRGGRLRSRLRDAAVRRPPGQRRAGYPLLHAQPLAGDARHPLRSAHDGALARQR
RRL
>A0A353B4N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MSLKNILTSDRPVVSFELFPPKSDAGVDDLMKNVGELAELSPDFYTCTYGAGGSTRDRTL
DVTRRVREQTSTPTASHLTCVGSTRDELRGYLKRAQEAGVDYIVALRGDPPKGEETFQAV
EGGLSYANELVELIKADFPEFGILVAGYPEVHQEAPSAEVDLENLVRKVNAGADAIVTQL
FYSNDDFFRFREKCEAAGITIPILPGLLPVLSLKQVQRIAGLCKAKLPTTFVERLSQQDS
PEWQFQVGVEHAIAQAEGLVAAGIPGIHFYVLNKVTATQQILSAVPQLGRQTV
>A0A355AH60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
VELVALIKKEFPEFRILVAGYPETHQEAVSPEADLEHLKEKCNAGGDTVVTQLFYDNTDF
FRFRDRCSSIGITKPIIPGLMPVTNFKQIKRIATLCKARLPNSFTHALEKAGDDADAQFE
AGVDYASKQAEELISNGIPGMHLYVLNKSPAAIRVLEQVGMTRP
>A0A2E8D261|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MTLSAHYGPGKLGLSFELFPPKTEAGQAALLKHVSKLVEFKPDFVTCTYGAGGSTRDKTL
DIVQGVKQDHGLPVASHLTCVGSTRDQLRSYLTEAQQRGIDYIVALRGDPPAGETDFKPV
EGGLSYANELVELIRSEFAGFGIAVAGYPEKHQEAPNAEIDLENLKRKVDTGAEIVITQL
FYDNDSFFRFRDRCDAIGINIPIIPGILPVTNLSQIQRITSMCGAVLPDAFVSKLGEQEG
DDWQFQAGVDFATQQVQSLIDAGVPGVHFYVLNKSQATSAVLRAITRPE
>A0A2D4WQ21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MDALDSGTAPTVSFEFFPPSTPXGWMNLDRRIXELVXLEPSFVSVTYGAGGSTRELTNDL
VVRLLEETKIPAVPHLTCVGHTRDEIDEILERYAKAGVTAILALXGDPPQDGGEPDSGDF
DHASDLVEHIQRFGDRHRHPFRIGVAGFPEGHPDTPNTLVGMTHLKTKVDAGADWICTQL
FFDNHAFLDWRDRCRIEGIHVPIIAGIMPIST
>A0A373ZGH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF15-31|TrEMBL
MKIRDIIGQEKATLSFEVFPPKKDTDFASVEAAALGIAALRPSYMSVTYGAGGSTKGHTI
KLANEIQEKYGVPTIAHLTCVCANKDSIRTALSEMKNAGIENILALRGDIPKNYDGQVFT
DFTHASELVKLIKESGDFCVGGACYPEVHPDSANKQDDIANLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRIREAGIAVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEVAAGIQANLSDILLV
>A0A2S6QWM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha9_Bin7|TrEMBL
MKGIDNIQYTNQAPLVVSFEFFPPKTEKMMESLWHSLSRLAPLGPRFVSVTYGAGGSTRI
RTHSIVSRIRAETDLEPAAHLTCVGASIAELDAVARAYYGAGVKHVVALRGDPAKGEARF
VPHPQGYDGSVELISGLRKIADFEISVGAYPEPHPASRGIQSDLDHLKRKLDAGATRLIT
QFFFDNDLFLRFLDKVRSAGIEAPVVPGILPVTNFQQVVRFSSMCGASIPGWFANRFDGL
DSDPSTRQLVAAHTAADQCFGLLDSGINEFHFYTLNRADLVFSICHMLGVRTAAHARVDE
EQS
>A0A5B0L4X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum brasilense|TrEMBL
MTSGIPSVSFEFFPPKTEKMEQSLWQAIQRLAPLSPSFVSVTYGAGGSTRERTHNTVTRI
QKETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPETEGGVGGRYVPHPG
GYAYAADLVAGMKKVADFEISVAAYPECHPEAPSAQFDLDNLKRKVDAGATRAITQFFFD
NDAYFRFLDRCAAAGITVPIVPGILPITNFARAVEFAGKCGAAMPQRFAETFEGLDSDPE
TRQLVAATMAAEQCQALQAQGIKEFHFYTLNRSDLTVAICRMLGVKAKQPAVS
>A0A6N8V194|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MTRPSISFEFFPPADAGAVQRLQRVMNLLVQLGPDFFSVTYGADGSTRSRTERLVCWIRQ
ELPVPPAAHLTCVGSTRSQTDALARRWWSLGIRHIVALRGDPPKGTDRYCPEPGGYRHAA
DLVRGIRAAADFEISVAGYPEPHPESPSPAADIENLKAKVDAGADRVLTQYFFDNACFLR
FRDRCSTAGITAPIVPGILPVTDFARVAEFSRRCGVTIPPHMVAIFEPLDTDARTREMIA
AGAAVSQCEDLRREGVNAFHFYTLNRARLSYAICWWLGLRGRIEAPSAGAADPNA
>A0A2V6NWX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MAHALDERLAREPLLCDGAMGTLLYARGVPLDACFDELNMNNPALVQAIHAEYIAAGADC
IETNTFGANRFKLAIHGLEARVREINLRGVKLARDVRETMGRDVLVLGAVGPLGKYLAPL
GALTEGEARTAFREQAEGLLEGGVDGFVVETMSDLGEMALAVEAIRAVTDLPIIAEVAFT
DEGVTFLGRTPAEVARALCALPVQAIGANCSVGSSTLYEVLEQIRPEAGARPIAIQPNAG
LPSRVGERLIYLSSPAYMADYAARMLAAGARLVGGCCGTTPEHISAMRKVMDRAPLARSA
GRVEAPARTRSESAPALRTAAPPTLLQRKLEAGEFVVTVELDPPRGHNIEKLVQGAKLLK
ERGAEIVDINDGSLGRIRMAVLPTGVLVRESTGLEINMHFTCRDRNLMGIQADLLGAHAL
DVRNILAMTGDPPRTGDYVNATAVFDVDAIGLIGILQRMNQGLDATGNSIGEPTAFCVGA
ALDPAAAEPRLEIERMRKKIEAGARWFQTQPVYDLEGLDDFLARAGAPRVPVLVGVMPLH
SSRHAEFLHNEVPGITIPDRVRARMREAGDRGLAAGIEMAQETLRLVRRRYAGAYLMPSF
GRYEVVAEVLDALR
>A0A2V7I7F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MTNPLAETLGAGRFCYVVELVASGLTREARLLEVASRLAALPEVVAGSITSYAGGAMGRD
PIRVGTAARARGLTPNIHVTCVGEERHGLRKTLEDLQALGIENVFALTGDHPKAGPGQSE
PVFDLDSVQLVRLIAELRRGGMPFHVAVAVSPFKYVEADCVYQYLKLEKKIAAGADLAIT
QVGWDALKFQELKRHLDERGLTTPVLGNVYVLGPKAAERMATGQPPGCWVSPALLETVRR
ESAAKDGGLRARLERAARTVAVLRGLGYAGAYIGGTHDADHVARIIRRSEELGPRWEELA
GELSYGDPNGFYLYARPPHPALSPSGGEGSAFPPASGEGQSALPLPTGERVGVRGWLRRL
VPRVLDRMGRLLPVTRDTWLRRRLSALMRWIDRRPKLAAALERAELAVKRPMFGCQACGN
CVLGHMEYVCPQTCPKQMRNGPCGGTQLGRCEVVDRPCIWVGVYERAKAAGRIEALAAYI
PPPDRALQSTSSWINYFLERDSRPGR
>A0A7Z9IXG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MGVSFEFFPPKTPQLEKSLWCSVERLAPLNPVFVSVTYGAGGS
>A0A2V6XES8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
LNVTRPDVVARIHEDYVTAGANIIETNTFGANSFRLDRHGLGDQVRAFNLAGARLARKAA
GEDVWVAGSMGPTGLVPGVATQAELDLASATFAEQAVALVEGGADVLVLETFRHLEEIRI
AIEAARRGAPDTPIIATMAFDPSETVADGSGPEHVATTLRDWGADGLGVNCGDGPQIALA
IAERMRVVDLPLCVQPNAGLPRTVDGRLLYMATPEYFDVFARRTIQIGATMVGGCCGTTP
EHVRWMAKSGRMLGDPRTDVARARAVKIVEPVTVLEPTPLAERSAFAAKIAAGQFVVSVE
VNPAPGLDPSKALAGAKMLLDSGVDIVNVADAPRAMARMSNIAFCSLLLERYGIQPILHV
CGRDRNLLAQMAHLLGAHAIGIRNLVIITGDPPKVGDYPEATAVYDLDAIGLLQMASNMN
RGVDPAGKPLPGGKTSFLLATGLEPGAADLDKELARLEKKREAGAELIMTQPIFQTDLLE
TVLRRIEHLEMPVLVGVLPLVSYKNAEFLHNEVPGMQIPEVIRERMRKTPGGEAARKEGV
KIAREMLFAVRERVQGAYLMPPLGRYELALEVLDGLKR
>A0A7C9PUT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillatoria sp. SIO1A7|TrEMBL
MTQQSPATDTAQTVSPQPESQFRAAVKAGEFLITAEVMPPKGGNPSHTLEMASCLKGRVH
AVNVTDGSRAVLRMSPVAVSAILLQHGIEPICQLACRDRNRIGLQADLMGAHALGIHNIL
ALTGDPMKAGDHPDGKAVFDLESIRLLKAIDQLNRGLDWNDKRLSDGSLDLFAGAAVDPQ
LKSWSGLQRRFEQKLEAGAQFFQSQLICDFDRLDKFMTEIAAGTDKPILAGIFLIKSAKN
ARFINRAVPGVNIPDSIIERLAKASSPLREGMLIAAEQVKIASQICQGVHMMAVRREDLI
PEILDLAGISPLISK
>A0A2T0L654|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. BL18I3N2|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLVTLKPKFMSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHVSCIGSSKESLRAILNQYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLDNFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCGRLIDAKVPGLHFYTLNGAAATKAICERLAV
>D2C7Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga naphthophila (strain ATCC BAA-489 / DSM 13996 / JCM 10882 / RKU-10)|TrEMBL
MRKSLETGKCVVLEVLTPRGTNLSKFMEFTEEAWKTGIDAFTVTDMPMGRVRMAPWAASH
LLVESGKDVLMHFTRNTRNMIRIQSDLLGCHALGVKNLLLLSGDNPSHGDYPETTSVNDI
DILDLIRLTKLMNEGTDLAGNKIYGKTDFFVGGALNPFSDEDVERAKQKIEAGVDFLVTQ
PLFNSEVAKKIKEELNTKILASIVFFENAKQMSYFSNVPGIEIPDEIVNSAEKGDDYLKE
KSFESVLRFVEETKDVLDGFYIVAIVKDLEKIRKVVEIAKS
>K0DTU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia phenoliruptrix BR3459a|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLALLKPKFVSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHLSCIGSSKESLRAILNQYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
EARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCARLIDAKVPGLHFYTLNGAAATRAICERLKG
>A8G2F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus (strain MIT 9215)|TrEMBL
MKSKLQQTLEKKSKVITAELMPPRGGNPIRSLNIAQLLKDKVNAVNITDGSRAVMRMCSL
AMSKLLLENGIEPVMQISCRDRNKIALQSDILGANALGIRNILCITGDSVKAGDQKDAKA
VHEFESVKLLQQIQAFNKGIDPTLGELSDKKTFIFAGAAADPSCRNLRSLENRMRKKKEA
GAGFIQTQMVMEKQNLIDFCEKISNPLEMPVIAGVFLLKSYKNALFINKYVPGANIPENI
LNRLKDAKNPLQEGIEIAAEQAHDFMNIASGIHLMAVRAEHLIPDIIKKADLSLEY
>A0A1M6WKU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWOV1|TrEMBL
MKIVDILKQDKMSLSFEVFPPKKETSFENVKAATESIAALGPAFMSVTYGAGGGVSHFTL
DIAKNLKEKFNIPMLAHLTCVSSSKETVHQRIEDMKAAGIKNVMALRGDLTPELIEKGRD
NCDYHYAVELIRELKASNADFCIGAACYPEKHPESANQAEDIKHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFAG
>A0A836TKX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilaceae bacterium|TrEMBL
MKKTALSFEFFPPKTEEGIAKLRETRKKLAVFKPEFYSVTFGAGGSTRDRTMDTVFEMQD
EGYQAAPHISCISSSKAEIVGLLKAYQDKGIKRLVVLRGDVPSGEVSTGDFKYAVDLVAF
IRQETGDWFYIEVAAYPEFHPESLSAAKDIDNLKRKVDAGADSAITQYFYNADAYFQFLE
SCYKAGIHVPIVPGIMPIYNYTQLARFSNICGAEIPRWLRLRLEAYGDDLTSLRAFGTDV
ISELCEKLLLAGVPSFHFYTLNQAETISTIINNANLTR
>A0A8F7LYP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIKRFCDKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLSAYGDDTDSIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A7X5APR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas alimentaria|TrEMBL
MSTQQHPLGISFEFFPPNTEAGREKLIGVRDALAERSPRFFSVTYGAGGSTQDRTLNTVR
QVREAGITTAPHLSCIGSEKAQLRDLLARYREEGIDNLVALRGDLPSGMGGIGEFRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFERDVENFARKVKAGANLAITQYFFNADAYF
HFVDRARALGVEAPIVPGIMPITNYAKLARFSDACGAEIPRWMRKQLEAYGDDSESIAAF
GEEVITRLCQRLLDGGAPGLHFYTLNQAAPSLRIVDNIVG
>A0A2G8IR00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pumilus|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSIDEIKR
SFREQLYILLNEQPDGLLLETYYDMEEAKAVLEIARKETTLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPILENSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHINAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKSAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMVKAGEDKEKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKEPNVHVNYH
>A0A7R6WLR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 113-1-2|TrEMBL
MTARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A672ZJG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaeramia orbicularis|TrEMBL
MVNQVPRGDGSWQSFKSDSSGASTSGGDSSKDSSRCSTPVLEADRSDRLRDKMRRRTESG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTTHKITGYLEKAKRLGLKNIMALRGDPVGADWEEEEEGFNYAI
DLVKHIRSEFDDYFDICVAGYPTGHPEAGSYEEDLQHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIQQAVQMCRVLLDSGKVSGLHFYTLNREVATMEVLRQLGLWTEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSTKDA
LLQMWGDELMNEQSVYEVFTCYITAQPNHRGHKVMCLPWNDEPLAPETNLLKEELEKVNR
RGVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRV
NYHIVNVHGQNRTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWG
KLYEEESPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQVIDDMFELLDTTTFSFVYKFFI
>A0A7M3P5B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. LK12|TrEMBL
MPLSPGRQVTIRQALSMPSAGSIPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFASVTY
GAGGSSRDRTLRIAQRVSRQPLTTLVHLTLVEHTVDELREILRSYLSAGLTNLLVLRGDP
PGDPLGPWVETEGGLHYASELIELIKAEPEFEKFEIGIASFPEGHYRSPDLDHDTQYTLA
KLRAGAEYSITQMFFDIEHYLRLRDRLVEADPVHGAKPIIPGLMPITSLRSVRRQVELSG
AQLPSDLEERLIKAADGDEQANKDEIRKIGIEFSTNMAERLIAEGVPGLHFMTMNFARAS
QEVLHNLGMAPEWGTGQDMLRGGF
>A0A0A2VWM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beauveria bassiana D1-5|TrEMBL
MERITDKIAALPADGEYFSLEFFPPKTAMGFSNLRDRLHRMEQGLRPLFVNVTWGAGGST
ADKSLELAELCQRELGMTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRTDE
YRTTDDDESDNDGAADGQAFVWAIDLVKYIRKKHGDYFCVGVAAYPEGHADESHPLGQSL
AHDLPYLVEKVQAGADFIMTQLFFDIEAYDTFETTLRGHPSGAFQTIPILPGLMPIQSYA
MIKRTAKLSHAAMPPALLDRLNAVKGDDERVKAVGVDILSELVEQVRTVKTKTTPGRPRG
FHFYTLNLEKAVTFILERTHLIPDAPDEEEVVIVDAGPTSAPFLQVNGHAIPPPQRSHSR
SSRRHSSRAANQPGVGGNGRRGGRAGGSVAAQRARQHARHLRGRGCARPRGHLG
>A0A3S5CW76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermothielavioides terrestris|TrEMBL
MHIKDVLAEAERTGEPSFSFEYFPPKTAQGVQNLYDRMERMYNFGPKFIDITWGAGGRVA
ELTCEMVVQAQTYLGLEACMHLTCTDMGEERVNDALRKAYKAGCTNILALRGDPPRDKEK
WEATEGGFRYARDLVAHIRKTYGNHFDIGVAGYPEGCDDNQDEDLLLDHLKEKVDMGASF
IVTQMFYDVDNFLRWVGRVRERGITVPIVPGIMPIATYASFLRRANHMKCKIPDDWLAKL
EPVKNDDVAVRDIGKTLVADMCRKILAAGIRHLHFYTMNLAQATRMVLEELDWLPSPDRP
LKQALPWKQSLGFGRRGEDVRPIFWRNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEQNRKKWGEPTCIRDIANLFVRYLNKEIEYLPWSEAPVAEEAEVIKKEMID
LNKRGLITVNSQPAVNGAKSSHPVHGWGPANGYVYQKAYLEMFIAPELFPEIKRRIENHP
DLTYHAVTKSGNFETNAQSEGPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGTEW
ARCYDPGSPSRLVLEEMMNTWYLVNIVNNDFHRGQTIFEVLEGLEVRDLDKVPQPQVNGT
KSPAADPTNGAETSA
>A0A3G3GJV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Runella sp. SP2|TrEMBL
MTKITDYIQQANGKTLFSIEVIPPVKGNNINELLGNIEPLMDFKPPFIDVTYHREEYIEK
PLADGRIQQIVTRKRPGTIGICASIMHRFGVDAVPHVLCGGFTKDETEDFLMDLHYLGID
NVLVLRGDPAKPYKTFKPKTNGHAYASELVEQVVNMNKGHYLHEEVEPLAPTDFCIGVAA
YPEKHFEAVDFDTDFDYLKQKVALGADYIVTQMFFDNSKYFDFVQKCRAVGINVPIIPGL
KPLSTKKQLGILPKIFYLHMPQDLVKAVEECENDAQAKQVGIEWCTQQCRELMDFGVPVL
HFYTMGKSDNIYKIASNLF
>A0A443YK17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio sp. S3|TrEMBL
MKIIDALQHSERFLSLEFFPPKEQAQWPGFLDQVNRLAGLDPLFVSVTYGAGGKLQDNTL
EIAAAVNKRFGLTTMAHLTCVGAERDAIALYMDRLLKAGIENVLALRGDMPGGNPEAIWK
DFSHASDLVEFVKKGWPEMGISIACYPDAHPEASSIEDDLKWTCHKLDAGADFAITQLFF
DVRRYHDLVLRLRKRGTTQPIVPGVLPVLSLQSLNRILALCGANIPLRLYLELQEAHDRG
GDTAVRQKGIEIARRQIRELLALGAPGIHLYSLNNADICLDILTDLPELDG
>A0A1A6CAD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia miricola|TrEMBL
MKVTEHIAQSKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGEKYFEPTKGGNRYASDLVTQINDLGKGKFLHGEISGNDLNNSFCIGVAG
YPEKHLEAPSMQYDLKMLKQKVDLGADYVVTQMFLDNQKYFEFVKLAREAGIDVPIIPGI
KPLAVKKHLQLLPQVFKIDIPEDLVNAVSQCKNNEAVKQVGIEWCVQQCKELLDFGVPAL
HFYTMGKSDNIQKIVSEFF
>A0A519BPN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Acididesulfobacter diazotrophicus|TrEMBL
MDKNLFKDKLENNEFVYTSEVSPERGTDLSKIKIILKSLKDKITAFNVTDNQGANMKMSS
LAASIYIKSIGGEPIFQQTCRDRNRMALESDLLGASALGINNVLTLTGDYITFGDHKHAK
PVYDIDSVNLIEIIKGLNSGYDMNGNHLNGKTDFYIGAAVNPESNPLEPQLMKFEKKIKA
GCNFFQTQAVFSVENFEKFYNYYKNYNNIKIIAGIFILKSAKVARFMNKNIPGIYIPQSI
VDELENSKDPLKTGIEISARVAKGLKNKVNGLHIMAFGIEDSIPNFLKNFEEEE
>A0A345Q8M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. SK011|TrEMBL
MTTPNVSFEVFPPRTVDAAFKLWDTAQTLAPLSPRFFSVTYGAGGTTRDLTKDAAHVLRR
TSGLPVAAHLTCVGASRKETMDVARGFAKAGVTDIVALRGDPAEGAATFTPHADGFQNSC
ELIEALAETGKFNIRVGAYPDLHPEATDQQASIDWLKRKFDAGADEAITQFFFEAETFLR
FRDACDKAGIDKPITPGILPVVNWTSARKFADRCGTYVPDWVSQAFETALRDDRHDLLAT
ALCTEMCSDLIDEGVENLHFYTLNRAELTRDVCRALGVTPQVSLSDVA
>A0A3B9L961|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilaceae bacterium|TrEMBL
MNKNISYSFEFFPPKTAEGITNLRQTRVALAKLNPEFFSVTFGAGGSTRDRTMDTVFEIQ
AEGYVAAPHISCISSSKEEIKALLSAYQAKGIKRLVTLRGDVPSGEVSVGDFKYANELVS
FIRQETGDWFHLEVAAYPEFHPEASSASQDLINFKRKIEAGADSAITQYFYNTDAYFRFV
DACLAQGIQVPIVPGVMPIYNFTQLARFSSVCGAEIPRWLRLRLEAYGDDMTSLRAFGVD
VVTDLCQKLIDSGVKNMHF
>A0A4P5TV62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilaceae bacterium|TrEMBL
MAKKISYSFEFFPPNTPEGIKNLKDTRQQLSVFSPEFYSVTFGAGGSTRERTLETVLEIK
QEGFNAVPHISCISSTKAEIKALLDLYQQHNIQHLVALRGDLPQGALPGGEFKHANELVS
FIRQETNDYFHIEVAAYPEYHPEAPSAQVDIQNFKNKVDAGASSAITQFFFNTDAYFRFM
DECLIADIDIPVIPGVMPIYNINQLARFASNCGAEIPRWLRIKLESYGDDLPSLRSYGVD
VISELCETLIGWDVPSLHFYSLNQAGIISRIIQNLESN
>A0A090IIL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliivibrio wodanis|TrEMBL
MAYSHASHLESLNQNIAELDGSINVSFEFFPPSSEKMEETLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLVAAPHLTCIDASRSELVDIANDYWANGIKDIVALRGD
IPAGGGAPEMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQASRFAKMNNVKIPGWMAQQFE
GLDDDPVTRQMVGASHAIDMTRILSREGVKDFHFYTLNRAEHTYALCHTLGVRPKG
>A0A6G2SLC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7815|TrEMBL
MALGTPSTRTDHARTVRELLATGETSFSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVRYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDSDIGHFVD
KCRAGADYAITQMFFQPESYLQMRDRVVAAGCETPVIPEVMPLTSVKQLERFAQLSNASL
PSALKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A5I6QLY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Kiambu|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7S0PZE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccolithus braarudii|TrEMBL
RGQAEVKAREATRSSDRRLASPTHDLLNLFDPSIATMSAVGCIDSRGSLPMVTKGKINEM
IDEWQKHTSEPFISFEYFPPKTDEGVAKLHRTIADMAQQQPLFMDFTWGAGGASAALTLS
LSTESQQLHDVMVNMHLTCTNQSKEVCDGGLEGAKKGGIRNIVALRGDPPKGQAKWEATE
GGFNCALDLCKYMKANYGDFFSIQVAGYPEGHPDRITKVSELGREMSAEEKARVVDVDGV
LHVCADEEFAKEMAYLKEKCDAGADVIITQLFYDFEVFKTFVAKCRAIGIKAHILPGIMP
LNAYGGFKRMTGFCKTRIPPAMAAKVESLSGDHQKAEFSEFGVAYLVELCQKLAASGLVP
GLHFYALNQADKTYQIMKRLGYLQDPALPRKVSRSAQLDVTLELLKHIEANGGSPEDSSR
VLCAAAAAKKM
>A0A844BJV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum strictum|TrEMBL
MSAPRVSFEFFPPKSLEASFQLWETVQALAPLKPQFVSVTYGAGGTTRKLTHEAVETIHN
RYGVNVAAHLTCVDATRAETLEIVDAYARAGVTEIVALRGDPPQGQGAFVPHPEGFANSC
ELIEALAARSLFRIRVGAYPEPHPESRGVGHDVQWLKRKFEAGADSAITQFFFEAETFFR
FREECDAAGIDGSRIIPGILPIEKWAGVRRFAERCGTRIPAWLDEAFDKAVRDGREDLLG
KALATELCTELMEGGVQDFHFYTLNKPHLTRDICHALGVLPAGHLEKVA
>A0A8J8HAA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoactinospora sp|TrEMBL
MALGRPSVLPDRVPTVREFLATGRRTFSFEFFPPKDDAGERQLWRAIRQLEALRPTFVSV
TYGAGGSTRDRTVDVVERIAHETTLTPVAHFTAVNHSTRELRHLVGRFADAGVRNILAVR
GDPPGDPMGEWVRHPEGVLYAEDLVRLIRQSGDFCVGVAAFPYKHPRSPSIESDVSYFVK
KCQAGADYAITQMFFDADDYLRLRDRVAAAGCDTPIIPCVMPVTAMGTIARSEQLTGAPF
PAALAARFEAIADDKAAVRSLGIDHCAEMSQRLLDEGVPGLHFITFNRSSATAEVFQRIE
TAPALSA
>A0A845RX13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. 4CP|TrEMBL
MFICELFQQKKVVSFEIFPPKLTSSIEVIYDTIDALAPLRPDFISVTYGAGGSTSKTTAE
IASIVENKYNINSLAHLTCITSSKEQIEETLTQLADSNVSNILALRGDIPKGAGETGRAR
DFQYASDLVAYIQNKHSFCLGGACYPEGHPECPDKDHDIENLQRKVDAGVGFLITQLFYD
NDAFFRFQEKVAKLNINVPILAGIMPITNRVQIERILALSNARMPQKLIKILDKFEHNME
ALKDAGIAYATKQIVELLANDIDGVHIYTMNKPQIAKDLVRNLDSLFYAVNSQETRKEGN
LA
>A0A0Q6A653|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. Leaf404|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEATPGGHSSAMELVHQINDLGRGKYLHDEQACDDHNKFCIGVAGY
PEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVNKARDMGITVPIIPGIK
PIATKKHLKLLPQVFKIDLPEDLINAVESAKNNEAVKQIGVEWAISQCKELLDFGVPVLH
FYSMGKSDNIKKVAGELF
>A0A6N7Q2C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polyangium spumosum|TrEMBL
MSLVPPSIAPKPTRFLDAVRRGVLVVDGGMGTQIYERGVLFNVNYEELVVSRPELVQRIH
EDYVRAGAQVLETNTFGANRVRLTRHGYGDRVREFNLAAAGLARKAMGDRGYVAGAIGPS
GLVLAAFGEDDRARVRDAFAEQAEALAEGGADLLMVETMRQPEELFLAVDGIRKAVGDSL
PLVAEVSVDADLTLSDGTPVADVGARLRDLGCDVIGVNCSDGPQVVLAAIEKLLPLGIPL
AALPNAGIPRRVDDRFIYVSTPEYFGVFARRLCKLGVRLIGGCCGTTPEHIRRMAAAARM
EASAAAGACDDPGPLWVGFSDSSIPPEPPVHVTSGQRPVATRDKSKLAGKIGQKFIVSVE
VNPPVGLDPRSAIAAAKMLVTGGVDVINIADGARAQARMSNLALAVLMQEELGIETLLHV
CGRDRNLLGQVAHLVGAHALGIRNLVVVTGDPPKMGDFPDATAVYDLDSIGILRLASRLN
AGIDPGGKPLGGVTSFFCATGAEPAALNYAREMERLALKKRAGAELVMTQPVYDVSVLDR
FLKDAEPLGLPVLVGILPLASHKNAEFLHNEVPGMQIPKDVRDRMQRVGSGPAARKEGVA
IAREMLAAVRHRVAGAYIMPPLGKYELALEVMDGIV
>A0A4Q1CGK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacibacter luteus|TrEMBL
MKSLKEKIEAREHGLLLYSFTPPKITTEKEKLQTIAEKQINRINNLAIDGLILYDIQDES
HRTNEQRTFPFIQTVPPEEYFRHYLNSIKAPSIIYKSIANQTKESFNEWLCNNKDLENFV
FVGASSSAQVAETNFALTDAYDLRKELHQHLMLGGITIPERHSKKGDEHKRIFSKTEKGC
SFFVSQCVYNVYESKNLLSDYHYDSIDNNYELKPIFFTLSPCGSIKTLEFMKWLGIEVPK
WLYNDLKHAKDILETSVRTSILIADEILEFAAQKQIPVGFNIESISNKKDEIDAATEILT
VVAGRLKQARKKTTVETVAEASPL
>A0A2X2GHC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia quinivorans|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGGGKPEMYATDLVTLLKDVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAVA
>A0A2X2HB81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia quinivorans|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGSGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAA
>A0A2A6I677|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. L18|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGVSIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADIAAEQIEDLVRRGIHEFHLYTMNRAPLVSAVLDNLGFCRRPAKSAGAAA
>A0A1W9W3D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_87|TrEMBL
MSEHKAGSNLEKVLSAGHFAFTGECGPPQGANVELLIEKANHLKGVVDSVNVTDNQTAVV
RMSSWAASLILLENGIEPNFQMVCRDRNRLAIQSDILGVYSMGIRNMLCLSGD
>A0A2N7SEC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium intechi|TrEMBL
MTARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>R9X9C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ashbya aceri|TrEMBL
MRISQKLRQRATTGPEEKRKASFSFEFFVPKTSQGVQNLYDRMDRMYQTQPEFIDITWNA
GGRLSQRTTELVATSQGVLGLETCMHLTCTNMSTALVDEALTRAYEAGCENILALRGDPP
LQGTWEPCAGGFRYAKDLVAHIRARYGDHFDIGVAGYPEGHEEAGGTELIEYLKEKVDAG
ADFIITQMFYDADLFLAWCDEVRAAGITVPIIPGIMPITSYAALLRRAKWCQVRVPPEFL
AKLEPVKDDDQAVREIGTVLVADMCRKILASGHVTHLHLYTMNLERASLMILERLGLVDT
GGAGVRRRPSANETLPWRKSLNPTRRKEGVRPIFWQRRPYSYVARTSQWSADEFPNGRFG
DSSSPAYGDLDLCGHTLLRQTYQRSLELWSTPRTLLDLAALVISYLKGDLKCLPWSDVPL
HQEADALLDSLIRLNEHLVLTINSQPKVNGAPSADPVVGWGPANGYVYQKQYLEFLLPKQ
HLPAFHAALTADFPTLTYFALDADDNLASNHPDDTQANAVTWGIFPGREVLQPTIVEKAS
FLAWKDEFYRILDDWRLSFHENGAADSAALLAHITSDYALVNIVDNDFVATADNIYCLLS
RFF
>A0A2Z5QSI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces naeslundii|TrEMBL
MTPQQPGYAGASARIDGDDVHDNEPTGPTAAAGSRAAGLSSAETGSARRLPTVSLELFPP
RPGKAASATWGRIDRLLATGPDFVSVTYRPTFVTDPAGGINGGEYEGSVRGTEVSRCKAV
PCVRAVQEQTNPSEFVLAHVLESSTIPSWRT
>Q9RVQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)|TrEMBL
MTRISLELVPRSRSKLRAELALVAEQFPGVDTVNIPDLTRFSTRSWEGCAFAPAPLRAIP
HVRAIDLNPREPLPMTGAFLAHGIQEVLVVTGDAPADMSHRVYNVDAEQAIRRFRAELPH
VKVYAGLDPYRQSFAAERDYLERKLDAGAAGFFTQPFFDMRLVEAYADIVPEGAEVWWGA
TTVTEEGSLNYWQTRNRAVFPRSFELTMDWDRQFAAQLLGFARERGQHAYFMPVKTSVEA
YLSGIL
>A0A1Y6LN39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymoseptoria tritici ST99CH_1A5|TrEMBL
MHITKKLAAAHEKGDATYSFEYFPPKTAQGVQNLYDRMDMMHGFGPAFIDITWGAGGRHS
SLTCEMVKVAQSAYGLETCMHLTCTDMELSKVDDALKEAYNAGCTNILALRGDPPREQEK
WVETQGGFRYARDLIKYIKKKYGDHFDIGIAGYPEGPDETTTADEHIVYLKEKVDAGGTF
VVAQMCYDAELFIEWVQNCRDAGIPESVPIIPGIMPISTHAAFIRRANWTQARIPPAWHE
ALEPIKNDDSAVREVGRDLIVEFCQKLMAAGIMHLHFYTMNLAAAVRMVLEKLDLTPSAE
SPHPDIKPLPWRQSLGLNRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
SLDEYGIGLKGTNEHNRKLWGEPQTIDDISKLFVKYMSGKVETLPWSEAPINDEANVLVK
DLIELNNRGLLTINSQPAVDGVKSSHPTYGWGPRNGYVYQKQYLEVLVAPELIDTVIQRM
ENDEDITYYAVNHSGELKTNVTADGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYY
LGLEWSKCYEEGSKSRALITELTKSWYLVNIVHNDFRNQGGIFPIFDGLQVPGVNVEKLA
NGITNGHAENGKTTEENGKPETNGVPDGNNVVNGADKKA
>A0A2P6VW35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon SW_10_69_26|TrEMBL
MSFATELREGSQPWTLYEVIPPDRSAPRETIADQAAYIANLLVDHGIDAINIPEIRNEER
NGDRVAGFMEKYDPRNFGMTIQDVFDGDIDLVVNHAVVYDEADAQREWFRATYEKFGIDS
VVIVGGESSDVDYPGPSVPAAAQLAREVGQDVGLDPCLGAITIPTRRREDLDEPERMLAK
IDDGAEFFTSQVIYEADSTRQLLVDYDRACREHGVDPAPVFLSFAPITGRKDARFLEWLG
VRIPDEVKNWVFQARANPLDRSVRVAEHLLREILTFTDRRDLDVPIGINVEHIMRYNFDA
SEVLLDRLDSLLDWHELENQRT
>A0A7T4KKC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus necator|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLENFVRKVKAGANSAITQYFYNADAYFRFVD
DVRATGLEVPIVPGIMPITNYTQLMRFSESCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A1H0LH06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus singaporensis|TrEMBL
MKSGSNLEKVLAAGHFSVTAECGPPRGADPDIVRKKAALVKGNVDACNVTDNQTSVVRMS
SLAGCMLIKEQGIEPLIQMVVRDRNRIALQSDLLGASALGVRNLLCLSGDHQKFGDDPQA
KNVFDIDSMQLIHLAKTMRDEGIFPSGDKLEGAPKFFIGCAVNPFADPFEIRVPRFKMKA
DAGADFVQTQCIYNMEKFKKYLELAKRENLHERVKILAGVTPLKSAGMAKFMRRMVAGID
IPDEVVDRIAAEPKEKQAAKGIEMCIEQIQELKEMEGIAGVHVMAIEWEEKLEEIIGGAG
LLPRPLVQ
>A0A2E2SKV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagaceae bacterium|TrEMBL
MKITEHLKKAAGKTLFSFEIIPPKKGNNIQELYDNIDPLMEFKPPFIDVTTSREESIYIE
KDGLLDKKITRMRPGTLGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIENV
MALRGDAMKEEQYFQPTKGGHDYACGLVSQIADLNKGRYLNNVIETESCSDFCIGVAGYP
EKHLEAPSLKTDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVKLVREAGIDVPIIPGIKP
IAVKRHLQLLPQVFKIDIPQDLIDSIEDCKDNKAVRQVGIEWAIQQSKELMDFGVPVLHY
YSMGKSDNVQAIASQLF
>F4A1X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mahella australiensis (strain DSM 15567 / CIP 107919 / 50-1 BON)|TrEMBL
MTALSHLQAVLKQGHFAVTAEIGPPMSANVNLVRQKAGYYKGYVDAANITDNQSAVVRMS
SIATAAIVQQEGVETVFQMTCRDRNRIALQSDILGAAGLGLKNLLCLSGDHQSFGNDPQA
KNVYDLDSIQLIHTVKGMRDDKRFINGKEIKTEPQMFIGAAAHPFAQPTELYLISMGKKI
AAGVQFFQTQAIFDVEGFGDWMKAVREMGYHKQAYILAGIIPIKTARSLKIMNDTVAGIR
IPPDLIKRMDSADNQEEEGMRITLEIIEAVRKIDGVAGIHLMPVSSEQITPVVVQRAGLY
PRPQAEVQ
>A0A1Y5EBU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium 46_93_T64|TrEMBL
MTLSIGSHEGLMEGRLQNAGRRNPVNVSFEFFPPKSDKMAENLWRTLERLAPMDPTFISV
TYGAGGTTRERTHEVVARVRQETNLAPAAHLTCVGASVGEIEEVAEAYWDAGIRHIVALR
GDPPEGENKFVARRDGFSGSAALIEHLKKMHDFEISVGCYPEIHPDASSSIADLDYLKRK
VDAGATRAITQFFFDPESYLRFLDRAEAHGINIPIIPGILPVTSYSSIKKFGAQCGTQIP
AWLTHLFEGLDDDPVTRNLVASMVAAEQCRILQKAGVSDFHFYTLNRADLVYAICHTLGI
RPKIES
>A0A1G1M079|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium GWB2_45_9|TrEMBL
MTFKEKIQAGKFILTSELGPPKGIESGRILEDVELVRGRVDAINVTDLQSSVMRLGSLAV
SIRLKEKGFEPVYQVTCRDRNRLALQSDILSAANFGIENILALTGDHPKLGDHPHAKAVF
DIDSVQLIQVIRRLEQGLDMAGKKLEGVLPKFCVGAVVNPGSDPLEPQIMKMEKKIDAGA
EFFQTQAVYDLKSFENFLSKTKHLKTTVIAGIVLLKSAGMAKYMNENVAGISVPDNLINE
MRDTKDKQAQSIEIAARLIKELKPMCQGIHIMPIGWDKLVPKVLDAAGL
>A0A2H0D9W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium CG22_combo_CG10-13_8_21_14_all_37_15|TrEMBL
MKVIEHLLKAKEPLISFEIIPPKRGGDIKSLLHVVDDLSKYNPPFIDITSHGAEIVYEET
PQGIKKKIIRKRPGTLGICALIQNKYNIEAVPHILCKNFTREETEDFLIELNYLGIENVL
AIRGDDNGFVKPVPHGRSANEFAVDLVSQVNAMNNGKYLEENLLDAKATDFCVGVSGYPE
KHFESPNLKLDIKYAKQKIDAGAHYIVTQMFFDNNVYFDYVNACKEEGIDAPIIPGLKIL
SLKSHLTNIPRNFYINIPEALAEEVMSAKPEHVLEIGVNWAAKQAEELLNRDVPSLHFYI
LQNSKPINLLMKKLNLHFKKLVVKK
>A0A263HFZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallibacterium anatis|TrEMBL
MSYAKEIDVLNRSIADLNGDINVSFEFFPPKNEKMETLLWDSIQRLKSLQPKFVSVTYGA
NSGERERTHSVVKAIKQQTGIEAAPHLTGIDASLEQLKAIAKDYWDSGIRNIVALRGDEP
PGYDKKPFYAKDLVKLLKEVADFDISVAAYPEVHPEAKSAQADLIFLKQKVEAGASRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFVQLQKMAKVTNVKIPSWMFKLYDGL
EKDQTTRNLIGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGVRPSLAA
>A0A853D8S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda sp. ARW1Y1|TrEMBL
MKITDHIKKANGETLFSFEIVPPVKGKSIQELYNNIDPLMEFKPPFIDVTTSREEYIYKE
KDGLLDKKLIRTRPGTLGICASLKHKYDVDTVPHVLCGGFTKEETEYLLVDCQYLEIENV
MALRGDARKEEKYFTPTKGGHQYATELVAQIQNINKGNYLHETFESSELTSFCIGVAGYP
EKHMEAPSLQSDLKRLKEKVDLGADYVVTQMFFDNKKFFAFVEAAREMGIDVPIIPGIKP
IAVKKHLHLLPQVFRVDIPQDLIDAVEACKDNKEVRKVGVEWAIQQSKELREAGVPVLHY
YSMGKSDNIMDIARELF
>A0A7Z7CE43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. OK076|TrEMBL
MKADLRSVMQERVLIGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
HETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGPNGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLEEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGVPMSVYPNAGAADYVD
GQFRYGASPEYFGQTAVQFADLGARIIGGCCGTTPDHIAAIAQALVEYTPAPILEPDPSE
SKPRIILHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVSFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATKHFKGIYLMTPFMFY
SMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A836GXB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania sp. Ghana 2012 LV757|TrEMBL
MSGLILDAIAAEDVGKWYTSYEFYPPRSEKAEEEFMKVLIPKFIRQSPVFLDLTWGAGGR
TSETTMRLCKDLQHAYPDTPINMHITCTNMPRGLIKETLDFAKAHGIRNILALRGDPPHG
EEYQANPDGFACAKDLVRYIHATYGDYFCVSVAGYPEGHPSRIAEDGTISDEDSQKELDY
LKEKVDAGASVVITQLFYDASLYVKFVKRCRERGIMVPILAGLLPITTYAGFKRMVSLCK
TSVPSDVRKRVEELKDNPEGLKEYGVEQCVQMIEHIRSSGLDYHHLHFYTLNSSAQTFKI
LKRLDALVE
>A0A1F2R9B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium RIFCSPLOWO2_02_FULL_64_15|TrEMBL
MQPFIDALASRVLVCDGAMGTMLYTRGVFINKSFDALNLTDPDLVARVHQEYVSAGADLV
ETNTFGANRIKLGSFGIAESLAAINAAGVAITRRVAADRAYVAGALGPLGLRIEPWGKIS
VDEARGYFREQAQALAAAGVDLFVLETFRDLNEMGAAIDAVRSVSDLPIVAQMTTEEDGS
TLDGTPPERFAPEIERRGATVIGLNCAVGPAPMLETIERMAAVTTMTLSAQPNAGMPRDV
EGRNIYLCSPEYMASYARRFVRHNVRIVGGCCGTTPEHIRQIKAAVGALAPGGKRPARSA
VAGSTRLTVGPDPSASSGLPRATTSSDEPAERVEGVPREKKSRLARQMALGRFVTAVELR
PPRGVDAGPAIERARALKIRGIDLVSIPDGRAGARLSALSLAVLVEQQAGIETLLHYSCR
DRNLLGIESDLLGAHAMGLRNLLLLTGDPGRIGGYPDATAVFDVDSIGLTNVVARLNRGR
DIGGQAIGSPTGFHFGVLVNPAMPILDEELRRFEYKVQAGAEFVVTRPVFNLRNFEQLLK
RIETSRLPIVANVSVLESASHAEFLANEVPGLDVPGTIVDRMRAAETPERARAEGLAIAH
ELILGLKPMVAGLQLGMPARSDDVALVLLDDLR
>A0A5C8EJ79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira aalborgi|TrEMBL
MNSVENFINKLENEKEFTFTLEVTPQAKFDLGYLVEKIKSSNIEKYIDAFIIPDSPFANL
KISPILSSLQLSQRLKTEKPFIITQTMRDKNSIALQNDLIGANYFDIRMVLALTGDPVVN
GNQKQAKGVFEGNSELLIRIIKNLNEGKSAGNFIFKEPLKKIYPFCSINSYSKNDEMLKV
RLSKKTASGVKAIFTQPIYKVETLKKFLNWIDEMPLKEMKLKEKPILFPGFFPVLSYKTA
YFIYYKLPGAYIPEEWLNKLKDASKKSEDEEKKVAFELSSNLFKDMLSVYKKMHIMSMNN
YDFVADLLKHIC
>A0A5C8F991|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira aalborgi|TrEMBL
MNSVENFINKLENEKEFTFTLEVTPQAKSDLGYLVEKIKSSNIEKYIDAFIIPDSPFANL
KISPILSSLQLSQRLKTEKPFIITQTMRDKNSIALQNDLIGANYFDIRMVLALTGDPVVN
GNQKQAKGVFEGNSELLIKIIKNLNEGKSAGNFIFKEPLKKIYPFSSINSYSKNDEMLKV
RLSKKTASGVKAIFTQPIYEVKTLKKFLNWIDEMPLKEMKLKEKPILFPGFFPVLSYKTA
YFIYYKLPGAYIPEEWLNKLKDASKKSEEEEKKVAFELSSNLFKDMLSVYKKMHIMSMNN
YDLVADLLKHIC
>A0A4S2CYR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium laevaniformans|TrEMBL
MSIVTSTPAALSSRVAGCPKSMAYGPCGGVNADGTCEVHPTPCVFLARELPVRWTGAAAR
ATDPEAGSGDPSTASTLAGRELVAIAARRPLVFTGFPVRALRADAVGTTAEALIGSVDAV
LSGDAGRSRVQFPPSYRAALIGATGLRLWMGFNTRDRNRTALERELLSLRALGVAGVHCV
TGDHTQTGDRPDARPVFDLESTTTLPRAAALGLLTSFAESPAAPPIAERGARVAEKQRAG
GRMCLTQYAGDAEEVAAFVALCRAAGSDVPVLPGVPLVVDREGAELLASFHAAKLPSGFI
DRLFAARDVRAEGIRLAVAYGQALIATGEVGGVVIAGGARPGDEAAYAADLATVARELGG
GS
>A0A378ZXK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pannonibacter phragmitetus|TrEMBL
MSTSSDARRSRGSESAPVQVSFEFFPPKTDKMEAALWSTIQRLETLSPSFVSVTYGAGGS
TRERTHRTVERILKETPMLPAAHLTCVGASRADVDAVVQDYWDLGVRHIVALRGDPQEGI
GTAYVPREDGYAYASDLVAGIKAIGDFEISVSGYPERHPESTDWQIEIDNLKRKIDAGAS
RVITQYFFDNNLFEAYLERIAKAGLSIPVVPGILPILNFDQVVKFSSGCGTTIPDWLSRR
FAGLDDDAETRKLVGAAVAYEQVMDLVDRGISDFHFYTMNRAELTFALCHMLGLGQGETA
RQVA
>A0A2V1IZ71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paramuribaculum intestinale|TrEMBL
MTIPELIQRKGSKGFSIEVLPPLKGKGIDQLFAGIDSLKCFEPLYINITTHRSEMVYKST
ADGLYQRVSERSRPGTVAVAAALQQRYGIPAVPHIICSGYTKAETEYALIDLRFLGITNL
LVLRGDKARHDNRFIPNTGGHAHAVELQRQINDFNNGTFVDGTTMDSANDSPFSYGVAGY
PEKHDEAPNRDIDIAWLKNKIDNGAQYIVTQMFFDNDSYFSFVERCRQSGITVPIIPGIK
PIVTKGQLTVLPKVFHVDIPTDLARAVMDCKDDVQAKEVGVEWMAMQMRGLYEAGVPSVH
IYSLNATRSVEKALRLVL
>A0A1F0XWV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC072B04|TrEMBL
MTTVHPALSFELFPPRSHASCESLLHTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSNAE
LHRIGVEYALNQCRTVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQSLSELEY
V
>A0A270BW52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter syzygii|TrEMBL
MSLNRLCVELIPRSAESLAQDVATVKSVFPAADTLNVPDLMRFPLRSWEAAAQLHPTFPR
VIPHIRAIDIAPNAPLPGAEQPGLEEILVIHGDPPADLSMRTYPNSTESIIRRYRKEAPH
LKIYAAFDPYRRAPWKELEDVARKKEAGASGFFTQPVFDYKLFDLCREWLRDEDVFWGLS
PVIGPRSRSYWETTNHIVFPKDFSTTLESNITFAQTVLRELAADQGCAYLMPVRIKLEHY
LPALLEAVS
>A0A2H4S5P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cordyceps militaris|TrEMBL
MEKITDKIAALPADAEAAAALCQRHLGRRRHDGRQVARAGRAVPARARHDDVPAPDVHQH
EPQARRQGPRRRQGPRHPQHSRPARRPPRKEEYRTASDDDDEAEGEAGDDFVMALDLVKY
IRKKHGDYFCIGVAAYPEGHADESHPLGQCLEHDLPYLVDKVQAGADFIMTQLFFDIEAY
EQFETALRQHPSGAFRTIPIMPGLMPIQSFAMIKRTAKLSHAAMPAAILERLHAVKGDDE
RVKAIGVDILSELVEQIRTVKRKTPGPRGFHFYTLNLEKAVTFILERTHLIPDEPATQED
AVVDGGPTSGPFLQVNGHAIPPPRSHSRSTRRHSSVGSDPHNRVIASTGRRTNPEWEATG
AEAAVPAAQLNARANTLAISEGEGALGREATWDDFPNGRFGDSRSPAYGEIDGYGVSLHM
SVTQAVKLWGHPATTRDIDDMFVRHVRGELPALPWSEEELLAESSTITPHLAALNAKGWW
TVASQPAVNGVRSADATFGWGPANGFVFQKAFLEFFISSADWAALRHKLQRPGVREVVCF
YAGNAAGDFVSSDSNSTVTATASSTNAVTWGVFPGKEIVTPTIIEEVSFRAWCEEAFGIW
GEWSRVYGRGSPSATLLSGIRDDYWLVNVIHHDFVDHQALWDLLLA
>A0A2H4SQD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cordyceps militaris|TrEMBL
MHIKDLLAETKRSGKPSFSFEYFPPKTSQGVQNLYDRMDRMYNFGPQFIDITWGAGGRVA
ELTCEMVLQAQAVYGLETCMHLTCTDMGMDKVNEALRMAYKAGCTNILALRGDPPRAQEK
WTATEDGFQYACDLVRHIRATYGDHFDIGVAGYPEGCDDNDNEDELIEHLKYKVDLGGTF
IVTQMFYDVENFIRWVAKVRAAGINVPILPGIMPIATYASFFRRCKHTGCNIPQNWLDLL
EPVKNDDVAVREIGKKLVVDMCRQLMAAGIHHMHFYTMNLAQATRMVLEELSWTPSAERP
LQQALPWKPSKGFGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRLKWGEPKSLRDIANTFVNYLNQDIDSLPWSEAPLTSEADSIKPALIE
LNQRGFLTINSQPAVDGVKSSHPVHGWGPANGYVYQKGYIELLVSPEIVDQVIPLVNGNP
SLTYYAVTKDGNLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFDAKSASRILVENVMDNWYLLNIVNNDFHDNSALFELFKDLKVDGLDTLVTVEVEKP
ATVQTGAAA
>A0A373QDD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium AM55-24TS|TrEMBL
MFIRDIFAQKKPVLSFEVFPPKKDSGLDNVISAVDELSKMPIDYMSVTYGAGGSNSKNTA
YIASHLKNNLSIPSLAHLTCVANSKGDIKVKLQEYKDLGIENILALRGDKPKDYDGEIFP
GYHYANELVEAIKDFGDFCVGGACYPECHPDSSSLDADIENLKVKVDAGVDFLVTQMFFD
NNEFYKFRDKLAKKGINKPITAGIMPLTNAGQIQRMAILSGGASMPSKFLRMISKYQDNP
EALKQAGIAYAVDQIIDLLSNDIDGIHLYTMNKPETAQKIVNVINNLFV
>A0A2M7PJG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium CG_4_10_14_3_um_filter_42_6|TrEMBL
MERTIIQYLAEAKKTLFSFELLPPLKGHNFDSIQQAIDPLVKFDPAFINITYHQQEVVYE
NLPNNLMKKHTVRKRPGTV
>A0A7M2RZW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio diabolicus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSAKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKATTGLVAAPHLTCIDATREELINIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRAAVGA
>A0A847EQ77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propioniciclava sp|TrEMBL
MPETIVDRLRSSDGPTFSVEFFPPSDDAGVQQLIGTVDQLQGLQPDWVSVTYGATGASRY
KTFSAVGAIRGQTAVSTMGHLTIAGQSAAEVVRAIQAYERLGVTHILALRGDPPSGGRFA
PHPEGLRTATDLVRLVKSLGDFTVGVAAFPDGHPEGDLDLDARILLAKEQAGAEFAITQL
FFDPAAYVSLVGRFRALGGTMPIVAGIMPVTVPSQIERFAGLSGSAMPADFEARLREVAD
DKAAFRAVGIDLVTQLCRDVLDAGAPGLQFFTLNRSTATAEILGRLRAEA
>A0A165L6S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula sp. K1|TrEMBL
MALGTRAVSDSQGVRTLLTSARFELMPFESFDEEITHLPDNATIAITTSPQLGIEKTVEK
TEEAAEMGYDVVPHIAARYVEDREQLEAIAERLEQAGITDIFVPGGDREEPAGEYESAHG
LLEALAETEYSFEEVGITGYPEGHDFIDDETLAESMAQKEPYATYIVTQLCYDPETVVEW
VEDIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDDEYNIRGVHIYTFNQTPDTEKWRHNRLDS
>A0A6G9WMJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio diabolicus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSAKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKATTGLVAAPHLTCIDATREELINIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFD
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRAVVGA
>A0A7G7VHI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas timonae|TrEMBL
MSQERMAIREHLKKEPLVFDGGMGTYYAQKTHTRGKGVELANIETPLVVEEIHTEYLHAG
AQAIKTNTFAANCSVYQGDTALVERILRSGWEIAARAAEPFDAYVFADIGPVTGLPPADI
LDEYRFLVDIFLAAGARHFLFETNSSTEGLVETAAHIKQVCPEAFVLTSFSAFPGGYTRD
GFFVEELIRTVTESGYIDAVGFNCVSGVQSMKELVHLLGTCTLPLSLMPNAGHPIVIDGR
TFYESAPDYFGDGLAAIVRDGVSIVGGCCGTTPEHIRALCRALVDSGRVSEVAGTRAART
SLAPSRSVFFDALKVGEIPIAVELDPPETGNADKFMAGARELQEAGVTAITIADNPIARA
RMDAAMLAGRVQRSLGLEPIPHMTCRDRNLNAIKSILLGLSAEGVHNLIAITGDPIPTAE
RDEVKSVYQFNSRKLSAFIKSLGERGDVVPFHVFGALNVNSIHFPSQLGLAKKKMEAGMT
GFFTQPVLSSRAKENLRTARDTLPGALILGGIMPVVSERNARFMESEISGIHVEQRIIDA
YHGLAREAAEELAVQLSLETAKDIEPYIDGYYIITPFARTALVARIVKELRRK
>B5VIK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain AWRI1631)|TrEMBL
MFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQHFSSRLDPIK
DDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNILPMESEFNAH
PLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDL
DLCGSDLIRQSANKCLELWSTPTSINDVAFLVINYLNGNLKCLPWSDIPINDEINPIKAH
LIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLK
NNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHI
LNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL
>A0A0K9I6H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocarbo indianensis|TrEMBL
MELKTDSNLEKVLRAGHFAVTGEVGPPRGSDPEAVREKAAHLVGKVDAVNITDCQTAMVR
MSSWAASLICKSMGLEPNYQMVCRDRNRIAMQSDILGAYAMGLNTMLCLSGDHPSFGDHP
MASNVHDLDSIQLIQMVRGMMDDGKFQGGAEIKRPPKMFIGAAANPFGDPFELRVLRLAK
KVAAGADFIQTQCIYNMQKFRDYMKMAVDKGLHEKTYILAGVTPLKSAGMAKYMATKVPG
MDVPDDVVKRIASAPKEKQAEEGIKFLCEQIEEMREIEGVAGIHLMAIEWEHKVPEILEQ
AKCLPRPQV
>A0A1V8T1S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rachicladosporium antarcticum|TrEMBL
MHITKKLAASHARGEPTYSFEFFPPKTSQGVQNLYDRMDRMHGFGPAFIDITWGAGGRHS
QLTCEMVKVAQSVYGLETCMHLTCTDMETSKIDEALKEAYNSGCTNILALRGDPPREQEK
WEQAEGGFRYARDLIKYIKTNYGDHFDIGVAGYPEGCDETTGSEEHIPYLKEKIDAGGTF
IVTQMCYDADIFIDWVHRCHAAGIPESVPIIPGIMPIHTHASFMRRATWTQCHIPPEWHE
KLEPVKNDDVSVREVGKELVADFCRRVLDSGTTMHLHFYTMNLAVATRMVLEELAVTPPS
NEHNPLLKPLPWRQSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAF
GELDTYGVGLKGTNEENRKLWGSPESNRDIADLFVGYMKGSVKSLPWSEAPINTEANVLQ
SDLIDLNGRGLLTINSQPAVDGAKSNHQDYGWGPKNGYVYQKAYLEVLVHPDLIDTVISR
MERDEDITYYAVNSSGSLRTNVPVDCGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFY
HLGSEWAKCYAEGSASKTLIKDVVDNWYLVNIVHNDFRQARGIFPLFEGLSAPGLSVTEQ
ANGNGNVNGHVNGGAENSDLSFRKKPETNGVYDGNNAVIGADHANMTNGQNGEVEA
>A0A503XQX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-3-2|TrEMBL
MIARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDTVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDDVTETQVDMVK
TAH
>A0A2L2K6S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio diabolicus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSAKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKATTGLVAAPHLTCIDATREELINIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRAVVGA
>A0A2G5V0X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis nigoni|TrEMBL
MTNTGEVQAIENRDTIKKIDSLSTMPYCGIDSGDENAVVTEKPVFETSKSWSLKNYELLH
ERIERLIDEKTPFFSLEFFPPRFVNGVPNFLERVERLSEGGSVFVDMTWHMGSDPANIDK
VTSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPGTE
LEDTNQFRALDMIRWIREEYGDYFSIGCAGYPLGHPQAPSYKADLQYLKAKCDAGANFVI
TQLFFEPETFEKFVADCREIGITKPIIPGIMPIMGYESIKRIAKLSQLEIPDHILEDLEP
IKHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNREGSIREILKALGLWKLEGDRV
FPWKNRSQHPIRCLESVRPIYWSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYL
SNLTTLRNGDDRLSMFGENIESIEDVKRVFINYITQTPNVSGKKVTVLPWTEAETGVQPE
TSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSE
KLIDIIEREYPVRVNYHAIDKDSSFDKTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFR
AWRDEAYQMWMAQWGDFYPKESKSYGVIKSIHDTFRLVTLVDNDFQKPSVLFDVLQKALE
QLYQ
>B1WZY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocosphaera subtropica (strain ATCC 51142 / BH68)|TrEMBL
MINHFRQAAQKKEFLITAEVTPPKGANPTRMLQMAQQLKGRVHGVNITDGSRAVLRMSSM
AASALLLQYGIEPICQMTCRDRNIIALQADLMGAYALGLRNILALTGDPVKAGDHKKARA
VFELESVRLLQMIDKLNRGIDFNDQTLPDEPLDLFPGAAVDPQCGSWSGLQRRFERKVAA
GAQFFQSQLITDFDKLDKFMHQIASNTDKPILAGIFLLKSAKNAQFINKNVPGVEIPETI
IKRLAEAEEPLKEGIKIAAEQVKLAQQLCQGVHMMAVKREDLIPEILDQAGIDSVVSK
>A0A0P9JIF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. antirrhini|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A3T0D315|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldicellulosiruptor changbaiensis|TrEMBL
MKSFREFLSQQDIVLFDGAMGTELLNRGYNKDFPLEWANISNPDLVKNIHNDYILAGSQC
IETNTFGANECKLKLYGFEGQVEKVNRSAVKLAKEVAGQTAYVIGSVGPLGKPVGSGFEI
DDKKAKEVYKRQLYFLLDEGVDAILFETAASTHEVFIAIEALKELDSNFPYIVQFSFSRE
LTTAYGEDIYRVIEFLKNLDADVVGLNCGNGPHQTLEALKIYSQHLKGPFSVQPNAGYPQ
LLQGRLVYSTSANYFASFVDEYVKCGAKIIGGCCGTTPEHIKAIKERIKTISKSVEIEVI
EKKEEQKSILKDTPSELSQKLGKKFVFTVEISPPKGIELEKTKEGVKLLKEAGADTVNIA
DSPMARVRISPIALAHILKEELGVESILHFTCRDRNLISLQSELLGAAALGVKNVLALTG
DPPSIGDHPQAKPVFDVNSEGLVLILNKLNSGTDYMGNPIGKATNFTIGVALNLNADDLN
KEIERLKRKIENGAHFIETQPIYEVESLERFFEKVDFKLPPILGGVLPLRSSRHAEFLHN
EVPGITIPDKIRERMKNSKDPVKEGIEIACEIVDRIKGMVSGIYIMPPFEKYEMAAEIIK
RFRA
>A0A4R3NEN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia alcalifaciens|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSAEMEQTLWKSIDRLKVLKPNFVSVTY
GANSGERDRTHSIIKDIKDKTGLVAAPHLTCIDASPDELKTIARDYWNNGIRHIVALRGD
LPDNSRKPDMYAEHLVELLKTEADFDISVAAYPEVHPEAKSAQADLINLKKKIEAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKITNVRIPSWMNRMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPK
>A0A357YAH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MSTFPGRSQAFLAQLQERVIIGDGAMGTLLYSRGIPLDGNFEHLNLVRPELVRQGHADYA
AAGARLLETNTFGANALRLGAIGLEKKVAAINGAGARLAREAAGADGFVAGAVGPLLPPR
GETTELTPEAKSEIFTQQMSALAEGGVDLFLLETFTSLEDLELALAVSATLGLPALAQMA
FLEEGRTRAGVSAEAAVRRLSAAGAAGLGANCGGGPRELLRVLERMARVTALPLSAFPNS
GFPEYHDGRYIYLATPEYFSAVARDMVAAGATLIGGCCGTTPEHIRALSAALAGSRPAPR
PRPVPSAVVPAATATAPPELAGTFLASWGKRTVVTVELDPPRGLDCRKLIVGARALTAAG
ADAISLAENPLARIRLGNIAAARTLHDEVGCATIVHITGRDRNLIGLHSDLMGAHLLGLR
NILAVTGDPVAVGGESGASSVFDLNSVGILQLLAALNGGHNLLGAELDGATSFLCGAAFN
PNLPSMDGQLRRLQKKIAAGARFVQTQPVYDVAILEELVTRTAPLGIPVLVGLLPLVSER
NAEFLHNEVPGITLPPAVRARMRGKHGAAGVSEGMAIARELIEAGRGQVGGWYLMPPFGK
IDLACELMASIRATSPAPLR
>A0A7V0QG22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MVKKISDILREKERVYSFEFFPPKTEKARKNLFETVRLLKELNPDFVSVTYGAGGSKREL
TMETADEIQRRFEIPTMHHLSCIGHSIYELKEIINEMQERDIRNVLALYGDIPEGVTEFR
PPADALSYCYQLCQLLRSYDDYFSVGVAGFPEGHVDAPDKETDLRYLKIKLDSGGQFVIT
QFFFDNKDYFDYVNRAREIGVTEKIIPGILPIIDYEKMLKFSEKMGATVTDEVHQIFKPI
KDDKEATYKAAVEFAVNQCRELLKNGAPGIHFFTLNKVEPTREILKRLLVDK
>H2YN66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciona savignyi|TrEMBL
MSPATNGVNGQAKQESLTEKILSRVKSKDPFFSLEFFPPRTEQGAANLIGRFDRMRQGGP
LFVDITWHPAGDPGGDKITSSTKIAGTVLNYCSLDTMLHMTCVKQTEETIKKNLEKTKNL
GIRNILALRGDADENWGITEGGFNYGVDLVRFIKKEYGDYFSICVAGYPNGHPDSTSYQE
DLLHLKEKIDAGGEFVITQLFFTADEFLTFVKDCREIGITCPIIPGIFPIQTNRSLVQLT
KLSKLTIPEEIQKVIEPIKDNDAAIRKYGIDLATDMCRSLLNSGEVHGLHMYTLNLEAAT
IQILKNLGLWCQDVAKTLPWKTSGNPERRENETVRPIFWTDRPKSYIHRTQKWDEFPNGR
WGDSASPAFGELRDYHLFFLRCRTSKDRLRAQWGKELTSETDVWKVFQNFITGAVNENGV
KVLETPWNDDGLSQETNLMSKKLSQYNARGVLTINSQPNVNAVPSTHPIFGWGDKGGYIS
QKAYLEFFINKRYAEALKVVLPKYHPRVNYHMINRCGAIDHTNADRSRPNAVTLGHLCRQ
RDYSTHSRGPDQFYRLEG
>A0A845QJX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerotruncus colihominis|TrEMBL
MKLAELFNQEKTIFSFEVFPPKRNNPIETIYQTLDELQEIKPDFISVTYGASGSLADNST
CEIASAIKQKYGIESAAHLTCVNSTKEEVSEVLRRLADNGVENILALRGDLVPDVPPKKE
FKHASELITFIKETKDYDFGISGACYPEGHLDSRNQVEDILNLKKKVDAGAQHLISQLFF
DNEVFYDFVDKARIAGINVPIEAGIMPVTNKKQIERMVSLCGASLPRKFTKMMSRYENKP
EAMRDAGIAYAVNQIVDLVSQGVDGVHLYTMNNPYVAKRISESVKSLF
>A0A803FT98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MITIFKDKKKKYNYESFDLKNKIKISFEVFPPKNIFLENQLFHSINILNKCHPEFFSVTN
SVCINMRDKTFSVLKKMFSLTNVKLFAHFTTIGLNESLIKDIAYKYWNYGIKNIIALRGD
LPSKYSEKIIYAVDLIKLLKSVNDFEILVAAYPELHPESHSLQEDLINLKNKVDLGVNTA
ITQFFFSVDKFLKFRDSCLRIGLKIDLIPGILPILNINQLKKFINMTNVYVPNWILDSFY
QNSENINKCIDLSVNIAVDLIINLYHEGIKNFHLYTLNQSDLSFKICRKLGLI
>A0A4D9CUE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nannochloropsis salina CCMP1776|TrEMBL
MGGRKIIDTIHSVLAEGGTTLSLEFFPAKTEEGMGNLLARIEDMVARLQPTFVTLTWRSA
FADESLWLKIGGIVQREFSVDVLLHLTCHLPRADLVRVLQNARDAGIRNILALRGDPPIG
EDRWQPVPGGFSNAVELVHLIRELHGDHFCIAVAGYPEVHTECWNSPDLPPSEQSFAQDL
TFLKDKVDAGADLVITQFFYDVPKYISFHDKCREIGIPAHIPILPGYLPIQNYASFRKFT
SWCKTSVPNTIDKALEKVKDEDEQVKALGVQEALRACRQLLDHGHRTLHFYTLNLESTVT
SVVEGLGLLPKANLRELSWQRHKASGNRVRAKGGPAEEVRPIFWANRQTSYVSRTNDWDE
FPNGRWGDSRSPAYGELSHYYLEFKRPKVDRQMLWGIPTKHEDVYNVFVRFLDGKVGSLP
WCEQAPAPETSAISSNLKFLNANGYLTINSQPAVDGRPSTDPEVGWGGPGGIVYQKAYVE
FFCSPDKLKVLMEEMDRHPNLSYHAVNVKGQEYTNTRSARVNAVTWGVFPGREIVQPTVV
DSVSFGAWKDEAFELWLTQWATAYQEGSLSRMLIHEIHDTFYLVNIVDENYGGDKTAIAE
TEDAVRLEHKSEGNDVTRLENTVNRHLDIFSLFKCVITRGFTSDQLFHFASETQRESEHL
YAVVKELKAINHDTANENRMLRTSLMQTQQEIADIKSELKRLRIQRGLDLIKPTTGFLHS
GQHAAAGAITPLVASNTICKNA
>A0A533QJZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Jettenia ecosi|TrEMBL
MIENRSDIKSGSNLEKLLRSGKFAVTAELGPPRGADRSAIEKKAKILKGYGDAFNITDCQ
TAVVRMSSIASGRIVLDAGVEPIIQMTCRDRNRIAIQSDLLGAAALGLKNLLCLTGDHQK
FGDHPMAKGVFDIDSVQLIQMVKTLRDEKRFQSGQELKASEPKFFIGAAENPFADPFKFR
AVRLAKKIAAGADFIQTQIIYNIKKFHEWMNMVADMGLHEKVFILAGVAPLKSAGMAKHM
KHNVPGMDVPDEVMSRMTAASAAKKGKEEGIKICLEVIEQVREIRGVAGVHVMAVEWEEA
VPEIIQQARLFPRPTV
>A0A1B6BFZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusibacter sp. 3D3|TrEMBL
MKIDQIFEQKKPVISFEIFPPKRDGDVNTVYKTIDELAKLNPDYISVTYGAAGTERSDDT
LLMASMIKKKYGIESLAHLTCVSSSRSELDAIFDKYEQYGIENILALRGDLNASHEANSR
AFKYASDLIEYIHDTRQFCIGAACYPEGHVEARSRTVDLINLKHKVSKGTDFLVTQLFFD
NEKFYDFRNEARSLDIEIPITVGIMPVLNRKQIERMVELSGATLPDKFKKILMRYEHNPE
ALQDAGLAYASEQLIDLLSTGVDGVHLYVMNKPEVAKRLVSNIESIVSVLRSSGQ
>A0A2W6SAV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp|TrEMBL
MTLNDLAAPLYADLSGDARVSFEFFPPRTEKMEAQLWSAIETLTPLAPEFVSVTYGAGGS
TRERTHATVARIAQETPLSAAAHLTCVAASKSEIAEIANAYWNAGVRHIVALRGDPPEAG
GRFEPHPDGYSGAAELVEGLVKLHPFEISVSAYPEVHPDAASAQSDLDNLKRKLDAGATR
AITQFFFSPDAYFRFMDKVLAAGIAADIVPGIMPVSNFAATQRMAAMCNTTVPDWMGRLF
EGLDDLPAARQLVSATIAAELCRKLHEGGVRDFHFYTLNRAEMSYAICHLLGLRPKAAVT
PTENVA
>A0A344L956|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis albispora|TrEMBL
MVLRGDPPGDPRARWIAYPQGFTYAAELVELVKSMGDPSVGVAAGFGCRAAGFGRPGSPA
GPLELGSWACPWLCQERLEGGCGLRRELAVFRKP
>A0A2N6F913|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MSRLQQQLADGRFVITAEVAPPKGCNPDPALDTAAAFDQVTAVNVTDNQGANMRMTPLVL
SGLLLQRGVEPILQLTCRDRNRMALQSDLLGAAALGIKNLLLLSGDHARFGDHPEARSVF
DLDSVQLLQAVSALEQGHDLAGKKLSAAPRFFPGAAVSPASEPFELMMQKCVKKAAAGAQ
FFQTQAVFCAAHLGHFMATARSEFEAPVIAGILLLKSARMAHFLNDNIPGVMVPEELILR
LESARQPLEEGVAIAREMVAAAREQCQGVHLMTLGREDLIPAILDT
>A0A2D5PCS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium|TrEMBL
MTTLSFEFFPTKTDEGTEKLLAVRDELAAYNPEFFSVTYGAGGSTRDRTYAIVNEIQRRG
IAAAPHLSCVGDSKAEIRELLTRYQEIGISRIVALRGDLPSGAGLGSSELRHANDLVEFI
RAETGDHFTLEVAAYPEMHPQAPNFEQDLENFVRKAKAGANSAITQYFFNADSYFYFVDR
VQAMGVDIPIIPGIMPITNYSKLARFSDSCGADIPRWIRKQLEAYGDDSDSIIRFGEEVI
TEMCHRLLEGGAPGLHFYTLNQARASLAVWKNLV
>A0A1H8DJC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. ne3005|TrEMBL
MSVTEFIHQDKAARRFSFEVLPPLKGTGTAKLFADIDKLREFDPAYINITTHHSEFVYRE
LANGNFERQRIRRRPGTVAIAAAIQQRYGIPVQPHVICSGCTVEDIEYELLDLQFLGISD
LLLLRGDKAKEDSRFVPTPGGHAHTTELMAQVKRFNEGFFADGTPIKNPGRGFDYGVACY
PEKHEEAPNLEMDMQYLKEKQELGAQYAVTQLFFDNEKYFSFVEKARQMGITIPIIPGIK
PMAKLSQLTVVPKTFHCDIPEALAREVVKCKTDEDAKQLGIEWTTQQCQELYQHGVHNIH
FYTVSAVDSVVEVAKRLL
>A0A2N6F775|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MGVVSIELVPRSEAALEKELQLVKNHFPAIDTINIPDLLNFDLRSWQGGAVAQKHFPHVI
PHLRAIDFDLDSESPFAGLSSAGDFAAMLVITGDRPQDMSRRVYRTSVIRMIRSLKAVYP
DLKIFAGIDPYRSGIKEELDYARRKVDAGADGFFTQPFFDLRLMEIYRDLLAGYDIYWGV
SPVTSDRSRDYWENRNNAIFPPDFEPTMKWNRDFARRALDFIDESDGNVYFMPIRV
>A0A1E7IDC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium C00003093|TrEMBL
MSRFAEKLSRQQFVLTAEIAPPKGVDITSALEKAKRLEAVDAINITDNQGACMRMSPLAM
ARLLIEHGYEPILQLTCRDRNRMALQSDLLGAAALGIENLLLLTGDHPRFGDHAASRPVF
DLDSVQLLQVVDGLVSGTDMAGKALSAAPHFFPGAAVAPAAEPQQLVLKKFQKKIACGAR
FFQTQAVFQHSQLESFMAAAGRFQVPVILGVLLLKNVRMAEFLNRNIPGVQVPEDLLKRL
EGTTDPLAEGVRIAREMVALGREFCQGVHLMTFGHEDLIPQILAE
>A0A5D0WQ14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. BW1|TrEMBL
MTVTTRRAEAATSAPCGDTPLFGEMAGDIAVSYEFFPPKTEKMEAQLWDAITELAPLAPK
FVSVTYGAGGSTRERTHATVARIRRETDLVPAAHLTCVAASKAEIDEIADEYWDAGVRHI
VALRGDPQPQDNGIFRAHPEGYASAAALVEGLRKRHDFEISVAAYPEMHPEASSAQSDLD
NLKRKIDAGSTRAITQFFFSADAYFRFLDKALAAGITAPIVPGIMPVTNFAAIRRMSANT
EIPTSLEALFSDLDSRPGPRALVAAVAAADLCKRLYDGGVRNFHFYTLNKADQTYAICQL
LGLRPKETV
>A0A1B2D0X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas aquatica|TrEMBL
MNVANANLSSFPISFEFFPTKTPEGAAKHVQVRQDLYARKPEFCSVTYGAGGSTQAGTFS
MVRDIQAEGMQAASHFSCIGATSDKVRAELQQLQDMGVRRIVALRGDLPSGYGLGGEFHY
ASDLVAFIRREFGDWFHIEVAAYPETHPQARSPEADLKAFATKIQAGASSGITQYFYNAD
AYFRFVEGIQALGVSAPVVPGIMPITNSSQLMRFSDATGAEIPRWIRLRLQAYGDDVTSI
RAFGLDVVTRLCEQLRDQGAPGLHFYTMNQSAATLELCDRLGL
>A0A383XPR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Abyssibacter profundi|TrEMBL
MSELQFSFEFFPPKGEKGATRLAEVRKQLAALQPAFFSVTFGAGGSTQSGTLETCIATKQ
DTGCDVAAHISCIGSTRERISQLLDEYRQAGINRLVALRGDLLPGMTDPGEFRYANELVS
FIRETTGDEFHIEVAAYPEYHPESPTPDADLDNLVRKVQCGADAVMTQYFYNVHAYEDLV
ERLAARGVRVPVVPGIMPITNHDQLIRFSDRCGAEIPRWIRRRLEAFGDDSESLRAFGLD
VVAQLSRNLLDLGAPGLHFYTLNRAAPTLELWQALRLPMPAAA
>A0A5N8AEL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp|TrEMBL
MNTPVIHPNWDLPPASATDGYSLEITAKDADSLREAAASIPAGTSIAVTFLPGEDPAARL
AATKTVRELGFEPMPHFSARRITSQEEFETYLNAVVSEAGVKRCFVIAGDPSEPEGPFAD
SSALIDTGAFERAGIEVIGIGGHPEGHPNMTEEETFEVLAKKTANITARGMSPLIVTQFG
FDTDRFLAWLKELRARGIDAPVRIGIPGPAGIKTLLRFAARCGVGASASVMSKYGISITK
LIGTAGPDKMVDAMAAQLGAEHGRVRLHFYPFGGIAKTVEWVNEYARRH
>B8BRT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassiosira pseudonana|TrEMBL
YSFEFFPPKTEPGLDNLLTRIDRMCRRLDPLFVSITWGSNGSTLSRTLAVASHAQRFACV
DVLLHLSCTGLTREQIGHVLAMAKSSGVHNILALRGDPPQGKRAWKEGDVSGGECDRAID
LVKLIRRLHGNYFGIGVAGHPEGHPSSQKGDNGKALEMQHLKEKLDAGADFVISQFFYDV
NVFLDYVKRCRKVGIDCPIIPGIMPVQSYSSLVKMTQFCGISVPSAVMDRLSNIRLDDEA
VKQVGCKIVAEMCEQILSAGLEVDVDGFHFYTLNLERSTTRILTSLGAGSISEQARSTRR
VLPWKPSAMENRSKEDVRPINWSNRPKSYVMRTDDWDEFPNGRWGDSTSPAFGELSDLSH
FCSFTLGSDEDRRAMLGHNPQAESDVYEVFARYVEGSVPHIPWCETPLQPESFLIQPQLA
KLNRYGFLTVNSQPPVDGLPSCHKVFGWGGKGGRVYQKAYFECFVSPSKANRLTQMVTDH
PSLNMYAVNNAGQELRVGVEEGGVTALTWGVFPNREILQPTIFDPDTFLIWAEEAFSLWG
SMWLNLYEYGSESYDLVQEIRDTYYLVALIDNDF
>A0A848ESJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera elsdenii|TrEMBL
MHTNELFAKKTVFSFEVFPPKRDIPVETVYPTLAELSKLHPDFISVTCGAGGTGGNRTVE
VAAHIKALGCETAAHMPCIYLTEEAALQNLKELKEAGIENILALRGDEVPGRERAHAFEH
ASDLVAFIKEKAPEFNVIGACYPEGHTEAKTLAADIRNLKTKVDAGASELISQLFFDNAL
FYRFLERCEIAGINVPIEAGIMPVTNKAQIERMVTMCGATLPIKFQRAIAKYGDTPESMR
DIGIAYAVDQIADLLANGVDGIHVYTMNNPYIAKKIAEAVKTLL
>A0A7S6SDD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MIFNKRGSRPFITDGSMAVELAKRGFAERPPDRYNLSSPTVVERIYHDFIQAGATLLQTN
TLFSNRFALESVMLSARVAELNRKGVWLARTASAGRVPVLGVIGPTGRLLQPLGPLNATD
AVECFREQAASLLSAGCDAIALKSFIDITELEIAISAVRAVSTDVDVIALKSFPEDAAVL
SGPYPKLFAKRITRLGIQAFGSNGTVGPQRMVGIIDALANDTIPLVAIPDVGIPTMIGGT
AVYHADPEYVGQAATRLAEHGASIVGADGGATVEHIAAIAQAVASASVGSKTPVAQVTEH
NAVPDSHPKPPTQWYTDLQSKFVRTVELDIPRGLDMSSVIEGARYLHTNGIDAVNISDGA
RARLRMNPISISRLVMDAVGIQCITHMACRDRNMVGLQSDLLGAHELDVRNILAVTGDPT
HIGDFPYASSVYDVDSIGMIRAMDRMNHGNDLMGNPLGSATSFSIACAVNPAADDIEREV
DRLAQKAEQGAIAAFSQPVFDDDALYTFLERISNIPIKFIVGIIPLRNLRHAEFLHFEVP
GMHIPSWVRKHMLENNESQQQATSAGIHLAVQMLSAVKNKVHGVYLMPPFKKYSVAVEVL
QRAGL
>A0A2E2ZR56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
MNDSINQREEARRAHDAPLFADMAGDIDVSFEFFPPKTEKMEATLWDSIQALAPLGPRFV
SVTYGAGGSTRERTHATVARIARETSLAAAAHLTCVEATKEEIDAVAEEYWTAGVRHIVA
LRGDPPTAGSKYQMHPGGYENAAALVAGLRKLHPFEISVAAYPECHPDSADEQADLDNLK
RKIDAGANRAITQFFFDPDHFFRFRDKAAAAGITAEIVPGIMPVMNYASVERMSKMCGTQ
VPSWMGRLFEGLDDHPEARQLVSATIAAELCRKLYAGGERSFHFYTLNRAELSYAICHLL
GVRPKPGAEAAAA
>D9TM14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIMB 9385 / NCA 3814 / NCTC 13789 / WDCM 00135 / 2032)|TrEMBL
MLNSKNLCQKLNNREFVVTVEMSTPKGADISNSIEEARKLYGIVDALNITDCPMANMRMS
PIALAHLLQNHLNIETIFHLTCRDRNLIGLQAELLGAYALGVRNILALTGDDPKRGDVPQ
ATGVYDVDSIGLIKIAKSLNNGFDYSGNRLESSTSFCIGTTANPNDLSKESIEKLKIKIE
NGASFIQTQPVYDEKILYRFLDAISKFGIPVLVGVLPLKSYKMAVNLNAKVPGIEIPDYI
LERLKNNGKGEGLKIAVEFINKIKNLVSGVHIMPLGRTDIVVDIINNVKNIKTDIKKEVL
>A0A5J6HTM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces coeruleorubidus|TrEMBL
MGAAGLRALLDSVRYEVLPAKPTEDQVLAHVPRDVVVTVTASPVRGLEPTLALTGRLAGH
GYRVVPHVPARLLRDDAHLREVVDRLRAAGVNDVFVPAGDADPPAGTYAGALPVVRRLTE
LGRPFTRVGVTGYPESHPLIHDDVTVQAMWDKREHATYIVSNLCFDPRVLGRWIVRIRHR
DVSLPVHVGVAGPVQRAKLLAMATRIGVGESTRFLARHPSWFLRFATPGGYSPERLLTPA
VADLTSPAAKVVGLHLFTFNQIAETERWRRALLDRLGA
>A0A3C0BP91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MKIINQFVSGRPNLSFEIYPPKHDSRLSDITATLDILAGLKPDFISVTFGAGGSSNNNKT
IELSRRIKDEYGIEPLVHLTCLCYSKSEIDDFLNQLDANGLTNILALRGDKREGVPEKND
FLHASDLIAYIRRTQGTKFCIAGACYPECHPQSPDRISDIRAIVKKKEAGAELLISQLFF
ENDMFTSFVENCRIAGIDVPVCAGIMPVINRNQIEKMVTLCGASLPERFKKIINKYDGNR
DALFDAGLSYAVSQIIDLCANGFEYIHLYTMNNPAVAKRIAEGVRNIIR
>A0A351YZW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MTIKEILDNKKTIVSFEIFPPKRQVNFDNVVNAAKELSALKPDFMSVTCGAGGGKRTNNV
EIAQKLISFGTPALAHLTCVRNTPESVRETVRDMKGCGIENVLALRGDMPRDLEEGETAL
VPELCHANQLVTILKEEGFCVGGACYPEGHPESANRDEDVDNLKYKVDAGVDFLTTQMFF
DNNMLYSYLYRLQSRGIRVPVFAGIMPITNSNQVARMVKLSSAYIPSKLLSFCDKFEHYP
EAMWQAGIDYATDQIIDLVSNGVRGIHIYTMNKPEVAIAIMKNIDKIIEAGNSI
>A0A5Q5BHB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. (strain MCS)|TrEMBL
MTSTDLQCPKRMQFGPCGGVRPDGQCEMRTGPCAFPDVVPWSGVEPASRPAQAPLVLTDF
SCAPFDEDDVAATARILGRSCDAVLVGEHQNRPDFPPTLMGRLLLEAGVTPWITLSCRDR
NRIVLEQELRGLRSLGVGTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGMVPAV
PETPTAPPVHARPARLVEKQRAGASLAVLNHVPYPDTITDFMATARTAGLSMPVVAAVAV
FTDVVSAAVLQGLPGLELDQSVVDEVLGAADPVSAGIAAAVAEARALLAIDGVDGVNVSG
LASASGTRVGAEIKAEVGRLVKAEVGA
>A0A7W6PJE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris|TrEMBL
MRARSAGPAAMTQLSFEFYPPKTDDQRAQLDRTAAKLKGYAPEYVSCTFGAGGSTLSYTS
ETVRHLKQKHRFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDL
RYASDLIAFIRAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYN
ADAYFHFRDAVQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDAD
AVRAFGAEVVASLCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A849T7L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionella sp|TrEMBL
INFKRKVSAGANSAITQYFYNADAYFRFVEDSRKLGITAPIVPGIMPIMKFSQLARFSDM
CGAEIPRWMRKTLEGYGDAAESVQAFGLDVVTQLCEKLIAGGAPGLHFYTLNQAGASLEI
VKRLGCQ
>A0A5Y7H4F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKESTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A607UCV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELCTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A841P5I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sangaii|TrEMBL
MIGSQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEQCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLGHILHDDITETQVDMVK
TAH
>A0A2D4TDJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haliea sp|TrEMBL
MPTISFEYFPPKTADGKTALLERTTPALQALDPGFFSVTYGAGGSTRDSTFGIVSALCER
GIDVAPHLSFGGDDENAISDLLQRYRDMGVRRLVALRGDMPSGMGGANQLVYASELVSFI
REHSGDHFHIEVAAYPEIHPQAESYNSDLQFLKEKLDAGANSAITQYFYNVESYFYFLDQ
CAAIGIDKPIVAGIMPITNFANLARFSRNCGAEIPRWICQRIEGYGNDQESVRQFGIEVV
TQLCQTLLENGAPGLHFYTMNQVEPTRQIRNNLGL
>A0A3M3G5Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. glycinea|TrEMBL
MAIICGSGLVRXXXXDKSAPTKYVFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVA
RQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQ
YKDAGIKRIVALRGDLPSGMGMASGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQAR
NFEDDLKHFVNKANAGADSAITQYFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKL
ARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQA
EPSLAVWNNLQLPR
>A0A1E7GPV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium S3730MH5|TrEMBL
MGFRQALESGKFLVTAEVGPDKGTNVEHLLKDADIIKDRVDAINVTDLQSSVMRLGSLAV
CHLLADMGIDPVFQVTCRDRNRLALQSDLLSAWVLGIKNVLSLTGDHPTLGDHPRAKPVF
DLDSVTLLETIGKLNSGLDMAGKELNGVPDLFPGAVVNPGADNEAALDLQIIKMEKKIEA
GAKFFQTQGVYDLDTFEKFMKRVEGFGAKVLGGVILLKSVGMARYMNKNVAGVFVPEPLI
KELKGAEDKVQASMNIAIRLIKGMKDLCQGVHIMALGWESKIPPILDEVGL
>N1UJX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Australis str. 200703203|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A543PU49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Humibacillus xanthopallidus|TrEMBL
MAHGTASSMTRAERFTRSIPDLIGGPLPSFSFEFFPPKDDASEAQLWDAIRRLEKVAPSF
VSITYGAGGGTRDRTVRLTQRVLEETSLTPMAHLTCVGHSVGELRSVVGAYAAGGVRNIL
ALRGDPQGGLGQPWVAHPQGLDHADELVRLVKGLGDFTVGVAAFPDGHPESDDISEDAET
LIRKERAGAEFAITQMVFDVDHYLRLRDELARRGSRLPVVPAIMPITNARQVVRMAELAG
QPMPASVTNRLERHGDDAAAVRAEGMAIASESSRRLLDEGAPGIHFITMNRSSATLEVFG
NL
>A0A401YST9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Embleya hyalina|TrEMBL
MAQNLADSFIAMSVGVTSSRRPGLGSARATAIHDLLASGKRSFSFEFFPPKTDVGERHLW
DALRRVEALGPSFVSVTYGAGGSSRDRTVDITERIATETTLTPLGHFTAVGHSISELRNI
IGQYADAGVRNVLALRGDPPGDPQGTWVPHPQGFTYAEELVRLLKESGDFCVGVAAFPEM
HPRSTNWDDDVKYFVRKCRAGADYAITQMFFHVDDYLRLRDRVVAAGCDVPIIPEIMPVT
NAGQIERFARLSGADFPTELADRVRAVGDDTAAVQEIGIEYGTRMSERLLAEGAPGLHFI
TLNRSIATLRIHDNLGLRESER
>A0A4Z1CHK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus liaowanqingii|TrEMBL
MTPPKISFEFFPPKTLEASFKLWEAARVLAPLAPEFVSVTYGAGGTTRQLTHEAVTTINR
QFGLQVAAHLTCVEATKGETMEIVQSYADAGIREIVALRGDAPKGSDGFVPHGDGFANSV
ELIEAIAARGDMTIRAGAYPEPHPDSPDSDADVAWLKRKIEAGASSAITQFFFEADTFFR
FRDKCAAAGIDVPIIPGILPVQSWAGTKRFAATCNTTVPDWAEEAFQMAALDGPEAQRTL
ATSLSVDLCEALIAGGVDRLHFYTLNRPELTRDVCAALGVQPTGDLDAVA
>A0A2E3Y1A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVTDYIKXSNKTIFSFEIIPPLKGKGIEDICEGIDPLMEFKPPFINVTYHREEYDYKKM
GNGLLKKVSIRKRPGTVGICAALMNRYKVDAIPHIICGGFNKEDTESALIDLKFLGVDNI
LALRGDPMKNESSFIPVDGGNKFAIDLIQQINEMNNGQYLYEETKNSPSNFCIGAAGYPE
KHFEAMNLASDLRHXKAKVDAGAEFIVTQLFYDNKKYFSFVKKCREIGITVPIIPGLKPI
TNQKHLTFIPKFFNTNFPEEFSNELEKCKTNEEIKKVGVEWSIXQSKELIDAGVPVLHFX
TMGKGQAVKEVASNIF
>A0A2H6BIU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylopila sp. Yamaguchi|TrEMBL
MPNHRLSRAARRPVRVSFEFFPPKTPEMEATLWRSIERLAPLDPTFMSVTYGAGGSTRER
THATVARMVTDTVVPPAAHLTCVSATKAEVDAVVDAYREAGVRHIVALRGDPANGVGGTF
EPHPGGYASTAELVAGIRRRAPEIELSVSAYPEKHPESPSLEADFDVLKAKVDAGANRAI
TQFFFDNDHYLRYVDQARARGIHIPIVPGIVPVSNFKQTASFAARAGATVPEWFAARFEG
LDNDVQTRQLIAAAVAAEQVLDLVDHGVKDFHFYTMNKADLVYAVCHLLGLRPTAATAKA
AAA
>A0A4R7NNE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromohalobacter marismortui|TrEMBL
MSTREHPLGISFEFFPPNTDAGREKLKGVRDTLAERRPRFFSVTYGAGGSTQARTFETVQ
TVRQCGIDTAPHLSCIGSDKGELRERLAGFREAGITNLVALRGDLPSGMGGMGELRYANE
LVEFIREETGDHFQIAVAAYPEMHPQAPSYEHDLQNFVRKMQAGADIAITQYFFSADAYF
HFLERARALGVEAPIVPGIMPISNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIQAF
GEEVVSNLCQRLLDGGAPGLHFYTLNQATPALRVLDNLRCDT
>A0A2E1XRF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVVDYIKNSNKTIFSFEIIPPLKGKGIEDICKGIDPLMEFNPPFINVTYHREEYDYKKM
GNGLLKKVAVRKRPGTVGICAALMNKYKVDAIPHIICGGFTKEETESALIDLKFLGVDNI
LALRGDPMKNESSFVPTKGGNGFAIDLIKQIDEMNRGQYLYEETLNSPSNFCIGAAGYPE
KHFEAMNLNSDLKNLKLKVDAGAEFIVTQLFYDNKKYFEFVDKCREIGIKVPIIPGLKPI
TNLRHLTFIPKFFNTNFPEEFSNELEKCKSNEEVNQIGTQWAIEQSKELINAGVPVLHFY
TMGKGEAVKNIASKIF
>A0A4P7HQF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus liaowanqingii|TrEMBL
MTPPKISFEFFPPKTLEASFKLWEAARVLAPLAPEFVSVTYGAGGTTRQLTHEAVTTINR
QFGLQVAAHLTCVEATKAETMEIVQSYADAGIREIVALRGDAPKGSDGFVPHGDGFANSV
ELIEAIAARGDMTIRAGAYPEPHPDSPDSDADVAWLKRKIEAGASSAITQFFFEADTFFR
FRDKCAAAGIDVPIIPGILPVQSWAGTKRFAATCNTTVPDWAEEAFQMAALDGPEAQRTL
ATSLSVDLCEALIAGGVDRLHFYTLNRPELTRDVCAALGVQPAGDLDAVA
>A0A257T035|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus ferrivorans|TrEMBL
STRERTFATVTMIRQDYDLEAVPHLSCIGSTEAGIREILEDYQKQGVRRIVALRGDLPEG
MENPGHFQHAADLVAFIHHFGGFDVYVAGYPEIHPRATSARDDVAHLVTKVRAGADAIIT
QYFFNPDAYLQLRDDLQRQGVDVPVVVGVMPITNFEQISRFSAMCGADIPQYVRRRMEAY
SDDPQSQYQLGIELLSRQCRLLLREGAPSLHFYTLNQAEATAAIWRNLSL
>A0A0Q7FEQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. Root1280|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKLVHQELQLLNPEFFSITYGAGGSTRERTLAAIADFN
GKGTPVAPHLSCIGDDKVRIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADNFDADIKHFAEKVKAGANAAITQFFFNPDAYFYFV
ERIQKEGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVIKLCERLIAGGAPSLHFYSMNHTEPNRQLVLDLGLA
>A0A7Z0CIS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Demequina lutea|TrEMBL
MTIRDLLAADRPTLSYELFPPRSAAAQDALPATMAMLARTHPDFMSITYGASGSTRGTSR
DVVQRLAEAHSVPPLAHLTCVDQSRAELTAVIETYLAEGVRDFLALRGDPPQGQADWRPH
PDGLLYASQLVELLREVAAAHGADISVGVTAFPAQHAIERWRQQGLDVLKAKQDAGADFA
ITQVFYEVPQFSALVADASAQGIGLPIVPEVMPLVSARRATRAAELTGVDTPSELVAALE
TAADDSAALAAGVAHAARLSTDLLDAGAPGIHIITFNRHDAALALVNALGLRGA
>A0A6M5Z0X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frigoriglobus tundricola|TrEMBL
MHIQDIFAQHPTTFSFEFFPPKTDEASEELFRTIAALQPLQPSFVSVTYGAGGTTRDRTH
DLVVRIERDTNLTAVSHLTCVCHSLAEMTAILDRYAASGIENVLALGGDPPKNLANFDRT
KDAFRYAEELVRFVRSRPGANGRGFGVGVAGFPEGHPGCPNRLQEMDHLKRKVDAGADYI
CTQLFFDNRDFYDFRERCDLAGIKVPILAGIMPITSKAGMVRMAELAAGAHFPAKLIRAV
GRCADDAAVARVGISWATEQCADLLHHTVRGIHFYTLNRSDATRQIYQNLGVESSAALRA
G
>A0A7Y2SQQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexales bacterium ZM16-3|TrEMBL
MHSNLQRRLAAGQVVVTGEMAPPKGAAPDRLIQLAEGLRTSVDAINLTDNQRGVARMSAL
GAAALLSQVGIEPIMQMTCQHRNRIALQSDALSASALGVRNVLCMTGDHPRIGDHPAAKN
VLDLNSFQLIRMMRKLREEAAFESGTSLKDAPQFFIGGVANPNVERAARLEKKIESGAEF
IQTQLIFDVARFRQWMADVRAAGLHQKAHILAGVMVLRRPNSAVYLRDHLPGTLMPDGIV
DRMLAAADSEHEGIVIAAELVNELLGVEGVAGVHIMSVDWTRSIPQIVERAGLLPRPPLP
ER
>A0A0K2MGG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium beijerinckii NRRL B-598|TrEMBL
MIKELLKNDILICDGAMGTYYSEVTGNDVSYCEFGNLNDKETIKRIHKEYIEAGAKLIRT
NTFSANTYDLGVSLETLMDIIKSGINLAKEVTRNTSVLIGASIGPIKTDNLDEFSNEVLE
EYKYIVDCFLKNGIDIFIFETFSNYNCLKKISEYIKYKNIDSFILTQFAVKPDGFTRDGL
SAAKLIKEVRNTKYIDAFGFNCGSGPAHILEMVKKINIENEIVSVLPNAGYPEIIHERTV
YPNNPVYFAKKVNEIRSFGVSIIGGCCGTNPSYIKQLTQIVNENSKVVNANAKAEPKVKS
FEKKAKNTFKDKLENGEFVVAIELSAPIDTDISRIIDGAKICKENNIDLVTVPDSPMSKV
RADSTIISSKIKREIGIEAMPHVCCRDKNTNAIRSSLIGSHIENIRNILAITGDPISDAS
KVETKSVFNLNSFRLIELIESMNEEIFKEDSIYVGGALNLNVLNKEVEYNRMMKKIEKGA
KFFLTQPIYDDNAIEFLKMIKERTNVKILAGLLPVVSYRNAMFLNNELPGVTIPDKYVQM
FSENMSKEEAQEIGVKITVEIGKKLKGIADGLYFITPFNRVNMLIEIIKQINA
>A0A351WT26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
MGGSSFLERIAGEVLVGDGAIGTMLYAKGVALDANFEHLNLVRPQLVLDLHAEYVAAGAR
VIETNTFGANYAKLSAIGLGGKVADINRQGGVLAKRAAAGRDVFVAGSIGPLGRGKQELS
PEQVRECFRVQSAALAEGGVDLLILETFAELEELEVAVAAAMETGLAVVANLAFGEGSRL
SGGIGAESAALRLAAAGADMVGANCGAGPLELLATLKRIAAVTQLPLAAYPNSGFPEYVD
GRYIYRTTPDYFASMALEMVAAGASLVGGCCGTTPEHIRVMAKRLQGSRPAARAAVTAVA
VSQPVEPPATAAKGFLDKWGKEMVVTVELDPPKGLDCGKVLAGSRALKEAGADAINLAEN
PLARVRMGNLALATVIRREVGIEVIAHVTCRDRNLIGLQSELMGASLLGVSSILAVTGDP
ASLGEDAGASSVFDLNSFQLIKLLSDLNRGVNALGNPIGAGTGFTIGAAFNPNGQRMEVQ
VARLAKKVANGACFAQTQPIYDLQRFEQMMEQTAHLGIPILPGVLPLVSGRNAEFLHNEV
PGIVLPDEVRKRMAGKVGEEGVREGLAIAREFIEAAIGKVGGFYLIPPFGKYEIAVELVR
FIXSGDQGSV
>A0A1H6A3F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. Su6|TrEMBL
MKITEIFKEKEVTLSFEVFPPKTDNGYPAVEKAAAEIAALGPDFMSVTYGAGGGTSKNTA
SIAADLQDKYHVPVLAHLTCVSSDKDHVKSMINTYKEKGIENIMALRGDIPKEGRTHFDY
NHATELIYDIKSIDPDICIGGACYPEGHVECARQSEDIQHLKEKVEAGCDFLTTQMFFDN
STLYQFLYRIKDKGIDVPVIPGIMPITNEKQVARSVALSGSTIPQKMKIMVDRFQDNPEK
LKEAGIIYACDQIIDLISNGVSHIHVYSMNKPDIAAGIMRNLGAIIK
>A0A060I8C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. IE4771|TrEMBL
MALKNEAQARNIGISFEFFPPKSEEMEGQLWETVSKLQDWDPDFVSVTYGAGGTTKAPTL
STVTRFLAQTPLATASHLTCVGATKDETHQVIDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGYDD
RPEERAKVAAEVAAEQIEDLVRRGIDEFHLYTMNRAPLVSAVLDNLGFSRRPAKSAGAAA
>A0A1M3ID43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium 43-93|TrEMBL
MKVTDLLASATKPIISLEILPPTKGKSIESIYGHLDPLMEFGPSFVNVTYHRAEQIMKKR
ADGTYEKVEIRKRPGTVSICAALMNKYKIEAVPHLICGGFTREETENALIDLNFLGVKNV
LALRGDAAANEKFFTANPNGHRYAEELVQQVLNLNQGKYMEEDIIDGVKTDFCIGVAGYP
EKHFEAPNIETDTYYLKRKIELGADYIVTQMFFKNSHYYNFVNRCKENNINCPIIPGLKP
LTSKRQLTTIPSIFNVEVPVDLVNELMKSAAPDAGDKIGEEWLYQQCVDLLKNKVPVLHF
YTLGKPQVVHNVLKRLF
>A0A1G8ME65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter subterraneus|TrEMBL
MLPTRVEIIPSEGIVERITAGVPTTTALTVTCLPHHGVERTVRTAAQLAELGYTVIPHLA
ARSISSQAELTGLLRASMSAGIGEVFVIGGDRKSPAGAYDSALPLLEDIAQYSGGLIRAG
IAGYPEGHPFLDRGAGVEALLAKQSLASHVVTQMCFSAPRIHDYVALLRRVGVELPVWAG
VAGAVPRTRLIALAAQIGVGSSLKFLSRKGPLARKLLSGDHYSPQGLVSELDGQAGSVAG
IHLYSFNNLDPVPGGPDLASAAGHGSALIQGAAHDH
>A0A0X3RRW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL F-5122|TrEMBL
MALGTPSTRTDRARTVREILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPSGLTYAAELVHLIKESGDFCVGVAAFPEMHPRSLDWDTDVAHFVA
KCRAGADYAITQMFFEPESYLRLRDRVAQAGCATPVIPEVMPVTSVRMLERLPQLSNAAI
PAGLKERILTAKDDPAAVRSIGIEVATGFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A4V3KVY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2E.F.Ca.ET.219.01.1.1|TrEMBL
MNVRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWQREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A523CUH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Scalindua sp. AMX11|TrEMBL
MDTQNNNNFKAGSNLEKLLRRGEFVVTAELGPPRGASRDAVEEKAKLLTGCADAYNLTDC
QTAMVRLSSIASGVMLLNMGMEPIIQMTCRDRNRIAMQSDILGAAALGMKNILCLTGDHQ
CFGDHPEAKGVFDIDSIQQLNMFREMRDEGKFQSGDELKVAPRLFLGSAANPFADPFKYR
APRLAKKIKAGSDFIQTQIIYNVKKFEEWMGHVRDMGLHKKVSILAGITPIKSLGMAKYM
KKNVPGLDVPDEIIQRLEGVKSKKAEGINICLETIERVRKIEGVAGVHLMAIEWEETIPE
IVERAGLLPRPTL
>X6N089|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reticulomyxa filosa|TrEMBL
MTGMSKKELLHFLDRCKVLGIRNILALRGGLSFFLKKKIIFFKSLCEVSHFILLYFFFFF
EFCNKKKKININSKYAKINTINNGKNADPPRGTDTWEPTEHGLEHGIDLVKLIRKHYGDW
FSVGVAGYPEGHVESENLEEDLKYLKQKVINGQADWVTTLLFYDVDKFLNFYDLCRANGI
NVPIIPGLMPIQTYNSFVRIVSFSNVTVPDEVWKQLEAIKEDDEKVRAFGIEYCTQMCKK
ILQRGINVRASFFFFFFVRYVMTRRFQRISLEDSSLKKKKKGTEKKNERTKLCRACTETV
RPIFWSNRDSSYIRRTQHWDDFPNGRWGDNRSPAFGEFPHHHLLYQQQKMTKKERLEMWG
KQLDTIEDISKVFVKYLSQKISKLPWCMESVDRETTIYMLEPLLILNQFNLLTINSQPQI
NGATSDDINVGWGQKHGYVYQKAYLEFFCSKEQLNELVGIMKSKYPTLAFMAVNNKGDFS
SYCRSANGNNNNSSGINNHTNAVTWGVFPSSEIMQPTIVDSVSFRQNTIQHSAIFLLWLM
NSIAWLRLIENICETWYLVNIVENDYVNGDIFRPFRDLLRKQIGDKYKTLNIDQKLKTVP
LISMRTQNEESESKDSE
>A0A396Z6S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira stimsonii|TrEMBL
MKKVSEIYGSRKGPVYSFEFFPPKTPEGDVKLMETVRELSQVHPDFVTVTYGAGGSTRDK
TIEIVTEISKNYSVPTVSHFTCVGANRDQIRETLQGIRSKGIVNLMALRGDPPRGEGEFR
KTPGGFENATELISFIRSEKMDFCIGGGCYPEKHPSAKSLEEDVRHLKLKVDAGTDFLVS
QLFFMNSAFENFLNLVRKVGIQIPVIPGIMPITSFSQIERFKTLAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFTVKQCRELLEMGVPGIQLYTLNQSHASYDIVRELKG
>A0A374VI55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. OM07-12|TrEMBL
MRVDEVFKQAASLGTVPVSFEMFPPKGELTLDTARKVAGSLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVNNILALRGDLPAGAT
EDDKPASEYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLSLSVEYLKQKQDSGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMSKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYATHQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A6T9Y7F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas macleodii|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIARDYWDSGIRRIVALRGDLP
KGVDKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVRFAGFTDVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGD
>A0A7L1JBM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smutsornis africanus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7C0XS82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon|TrEMBL
MSKLSENLKKKFIITCEIVPPRGPDLKNFIGEIQEIKKFKSKIYGINVVDNPGSMLLMSS
LAASILLMQNGIEPIFQLTCRDRNVLALESDLIAASAFGIENVLALTGDHPQCRSSDHKF
AKPVFELDSVKLIRLMKQMNQGKDAAGKDLNKPTNFFIGAALAPSAFSKEAEALKTKKKL
DAGVNFFQTQVTFYAPIVEEFLNIYERMFKEDIRKIVLLGIVPLYSYEMIKYLLMIPGVY
IPDSVKQRMKNAQDKMEAGIEIALELIDKARDLGLGGAHVMPAGKMVVLEKLLGEL
>A0A497RYQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon|TrEMBL
MSKLSENLGKRFIYTSEIAPPKGTDLTKFKEELKALKKIYPKLCGINVVDIPGSILLMSS
IGASIMVKQAGMDPIYQVTCRDRNVFGLQADLLTASAFGIENILALTGDHPSCRSSDHPK
AKPVYDLDSTSLIECMKRMNKGADMAGNKLYGKTNFFIGAALAQTPKPIEPEIYKTKRKL
DAGAQFFQTQAVFDTKQMWNFFDKYEKTFNEDIRKKVLVGLVSLYDYEIVKFIKTIPNVI
IPEKIERRIKNAKDAFIEGTDITIEYIDECKEQEVGGVHVMSAGNTDTLIRVFENVK
>W7MAW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella moniliformis (strain M3125 / FGSC 7600)|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFETTLREHPSGAFEGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKKRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPTNEWDILKAKLTSPELQDSVCFYASNARGDYLSSDSSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A2R7R364|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. HMWF013|TrEMBL
MFPTRIEIVPSTGIVEQVQTHVPLTTTLTVTCLPHHGIERTTRTAIQLGSLGYTVIPHLA
ARGIHDRAEMTRIMRECDAAGIREVFVIGGDRKQPAGSYEEALPLLEDIAQYTGGRMRSG
IAGYPEGHPKVQPLDLLDALLAKQHLATSIVTQMCFAAPKINDYAALLRREGVTLPVWAG
VAGSVPRTKLVSLATQIGVGSSLKFLSRKGPLARKLLSGDRYSPAPLVAELENHTGNIAG
IHLYSFNNLDAVPDEVGPASSPAALQSALTRGAST
>A0A1V6ASV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium ADurb.Bin147|TrEMBL
MKPFLLLAELVPAQGDDVRPIECFLRDYAGRKSEIPSGFRLAGVALPQNPRGIPMLDPAD
IFSIIAAKGPSGRGLWDDLDVVPHVTGKEQNAEALRSALMGFRAMGLTTVLAITGDKPAS
GKRVFELDSIGLLELVSELNFDAFQRAPVSPPAKRTVPSPEHPPAPGGFSRIGEMLAGPR
PGSASFASRFSSVPQFFALAAVSPFKYTEASLLQQYFKAAKKLQAGAQAFLLQMGWDSRK
SEELFRYFRQARLDAPVLGNVYYLSNANPAARLMNEGRMPGCFVSDELLAAVRREKAEAH
LERAACQVAMYRDLGADGVDLGGLPDFDALVRIAVRAGEIGPGWRQRRIILDYPPPPPAS
GPGLFYLYGPETEGGSAPRPPFRPSPRPRTFRQRRFDFLHRNFLTKGKRLCPAVAGTARA
FGLEKGEGSLYRWFHGAEAAAKAVLFACEDCGDCFLPENFGYCTLGECAKGLPNPPCGDA
TPEGRCGNDETRVCVAEPIFQAAAAAGKLDGLAETALPPRIAALEHTSGVLNYVFDRDHA
RGFPLIQIAELLHASIPRTAAAVQEVIKEGLIDAPPGAVRASGSAALGYLVSLIRRQAKQ
GAAYIDVNVDALSEDDPEFRKEILRFFVRLIRGHSLGVPVCIDSGSTEMLEAGLAAWYEG
GREGGRPSAAPLVNSVKTYTMERLLPLRARFPFKFIGLLVDEKTAGLDGAYGVEELQALA
RRIVRAATGSHGFAPGDIFLDSTVFPLSIDVPMEAAKPGYTFRAFETIRRLKADPEFRGV
HFSLGVTNAVRDLPGRRTGVTRAYLARAMELGLDAAIVNVFHGYGRRPPAPDLLAFVDAF
ARQDGSPEAVENALQAMMDFCRANRKK
>A0A069SJQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides distasonis str. 3776 Po2 i|TrEMBL
MKVIDLIRDSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKKKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIVHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A3R9VIS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC08241|TrEMBL
MALGTASVRSDRARTVRDILASGGTSYSFEFYAPRTEKGEQSLWKAMRRVEAVGPSFVSV
TYGAGGTTRGGTVKATQKIASDSTLTPVAHLTAVGQSVAELRNILGQYADAGIRNMLALR
GDPPGNPLGEWIEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVVEAGCETPIIPEVMPVVNVKTLDRLPQLSNAAF
PARVKERILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A2A6MI24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. NG07B|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMEIQLFQTISDLSVFAPAFQTVTYGAGGSTKAR
SLTTVKRMIREMGLNNTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGSA
YEPFPGGYESSASLVKALRARGDFEISVSAYPEKHPESADVAADIDMLKRKVDSGATRAI
TQFFFDNDDFERYLERVRRAGVQIPVVPGILPINNLTQVIRFAGLCGSKVPEAIISRLAH
LDDQPEERFKEASHIAAEQIVDLARRGLRDFHLYTMNRSPLLASVCELVGYQRRPLRPAP
APSYPAVATA
>A0A1H7FL52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jannaschia helgolandensis|TrEMBL
MPAVSFEFFPPKSLEGSFRLWDCISTLAPLAPEWVSVTYGAGGTTRELTREAVGTLGKQF
GLRVAGHLTCVDASREETLEVARGFRKAGVEDIVALRGDPPKGADGFVPHPDGFANSVEL
IAALADDGFNVRVGCYPDVHPEAKNAQADLDWLRAKIDAGASEAITQFFFDAETFLRFRD
RAAAAGIAAPIIPGILPIEDWAKTSKFAEACGAIIPDELRAAFEVAVRDDRADLLAIAQA
AELADTLVCEGCDHLHFYTLNRPELTRDVCTALGLAPRPSLSRVA
>A0A239KXL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus kyotonensis|TrEMBL
MTVWPGRNYDGSVTSDAVRGRSSDGWVTRTPSIVDRLRTTADSRIPFSVEFSPPRDQAAE
ARLWRAVREFEQMQPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSISE
LRSMVGAYADRGISNILVLRGDPPGDPLGDWEKHPDGVEYAEELVCLVRELGDFHVGVAS
FPEGHYRALDLEQDTRVLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVQFDPEQGAKPII
PEIMPITSLRSVRRALSLSGSALPRHIDDRFVKAAGTGTDEDRAAVREVGIELATSIGER
LIAEGAPALHFITLNFARATREVLTNLGLSPARV
>A0A8F7XUZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria sicca|TrEMBL
MNHAREIAALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHSIVKRIKQETGLDAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVMMGIDVEIVPGILPVTNFKQLTKMAQVTNVKIPSWLSKMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRPR
>A0A672HBW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salarias fasciatus|TrEMBL
MVNQKQRVEGAWQSSKSDSSNSTSGGESSKESSRCSTPVLDADRSDRLRDKMRRRIESGD
CWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQTREVITGHLAKAKHLGLKNIMALRGDPMGTDWEEEEEGFNYAVD
LVKHIRAEFDSYFDICVAGYPTGHPEAESYEEDLLHLKEKVEAGADFVISQLFFRADTFL
KFLDDCRRIGISCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITEVIEPIKDNDAAIRNY
GIHQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELMNEESVFEVFTSYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELDKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVSALLKVLKKYEPRVN
YHIVNVHGLNLTNAPELQPNAVTWGIFPGREIVQPTVVDPVSFVSWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELINDPVNPADSTAHSE
DPLSQLQAHHLSNVPISPVFKALTSKTALFMSPFP
>A0A7L3R322|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cettia cetti|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDSDRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCHQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVSAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>G2LMC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola str. Ak|TrEMBL
MRIFSEYHKDIVNQKLENVRNNIQCSFEFFPPKSSSLEENLWISVKHLTRLRPKFFSVTY
GANSGEREKTYDIVKKIYEKTGVITAAHLTCVNSTSDELKKIAQNYWKNGIKSIVALRGD
TLNKNYKHTIYALDLVVLLKKVADFDISVAAYPECHPESKNSKLDILNLKKKIDAGANRA
ITQFFFNIESYLRFRENCIKNRINVEIIPGILPVCNFSQLQRFSNMTNVQIPKWMFEMFH
GLDHDIFTQKIVGSSIAIDMVNKLSSEGVKNFHFYTLNQSDITYSVCHILGL
>Q6NGB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)|TrEMBL
MSAQPLPAAYQRTITDVISMPTPGQVPFSVEFMPPRDEAAEERLWKAAEAFHDLGASFVS
VTYGAGGSSRERTMRVAHKLSRHPLTTLVHLTLVEHTQEELEEILCTYASHGLSNLLALR
GDPPGTDPMAPWVPTAGGLDYAKDLIDLVRKTEQTSHFQVGIASFPEGHYRAPSIEADTQ
FTLEKLRAGAEFSITQMFFDVDHYLRLRDRLVKADPEHGSKPIIPGLMPITSLRSVRRQM
ELAGATLPKALEKRLLDAARGDEEAHRGDIRKVGIEVTTEMAQRLISEGIPDIHFMTMNY
VRATQEVLHNLGMAPAWGTQQGHDAIR
>A0A847US99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula argentinensis|TrEMBL
MALGTRTVPDSQGVRTLLTSARFELMPFESFDEEITHLPDDATIAITTSPQLGIEKTVEK
TEEAAAMGYDVVPHIAARYVEDRTQLESIAERLKQAGITDIFVPGGDREEPAGEYESALD
MLEALAETAYSFEEVGITGYPEGHDFIDDETLAESMTQKAPYATYIVTQLCYDPDAVLEW
VEDIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDDEYNIRGVHIYTFNQTPDTEEWRHGRLDS
>A0A642V372|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichomonascus ciferrii|TrEMBL
MKVSQKLQEAHKEGNAPTYSFEFFVPKTSQGVQNLYDRMDRMYDLGPQFIDITWNAGGRL
SNLTCEMVSTAQSALGLETCMHLTCTRMPRKMVDDALKDAYAAGCQNILALRGDPPQQGG
EWEAGEDGFSYAKDLIRYIRQQYGDYFDIGVAAYPEGHPEEPDADKLIPYLKEKIDAGGT
FVVTQMFYDAENFIKWCDKCRAAGINVPLIPGIMPISTYASFLRRANWCEINIPQNFMDR
LEPIKGDDAAVRQAGTELVADMCQKMLDSGHVKHLHFYTMNLERATIMVLEQLKLLENTP
TATPKLVNSNRQNPPLPWRQSLGLGRKEETVRPIFWKNRKQSYVSRTQDWDEFPNGRWGD
SRSPAFGDLEKYGVLFKQTPEKARELWGHPESIADLGKLFATYIDGNVKSLPWSDAPISD
EILPIKGHLLDLNRRGFLTVNSQPAINGLKSSHPVHGWGPANGYVYQKAYLELFVSPKVI
DQIIDAVEKDGNLTYYVTNNAGDLKTNSPVDGPNAVTWGIFPGQEVIQPTVVERISFLAW
KDEAYRLGAEWANCFDTDTSSRKLINELVDSWYLINIVHNDFQNPDAIFDVFKGIENF
>A0A7X1DNA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria sp. FSL_L7-0020|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGQKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFAQYGEVFRQEGARIIGGCCGTTPDHIRALRAGLQSTKPILEKEVRPIL
ELVPEEVEDAESGERLLDKVKERLTILVELDPPRTFDTTKFFEGAKALDAAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKAKINVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICAHFQGIYIITPFLRYDLSI
ELAKYVQNKQQVQIVSK
>A0A1A0LAP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp. 852002-10350_SCH5691597|TrEMBL
MSQASPYTGPVNSSAPVPSVVERLSAPHPGQVPFSVEFLPPKDAEGEARLWRAVRVFERL
NPAFVSLTYGAGGSTRDRTVRIAGQLATETTLVPVAHLTAVDHSIAELRSLVGAYADKGI
TNILALRGDPPGDPLGEWVKHPEGVSYAEELVDLIGELGQFHVGVASFPEGHHRAPDLDH
DTRVLVSKLRAGAEYSVTQLFFDVEFYLRLRDRVAAADAEQGAKPIIPEIMPITSLASVR
RMVELSGSVLPESVERRLIDAAGSGEQEDRAAVRAVGIDIATEMSQRLIAEGVPGLHFIS
LNFAKATCEVLDRLGVDTSDALPLVSSN
>A0A2U2SRL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ardenticatenia bacterium|TrEMBL
MSEVVHNGYKSGSNLERVLVAGHFAVTGELGPPKNHDANVIRRKAELLKGCVDAVNITDN
QTAIVRMSSIAAGVILIQEGMDPVIQMTCRDRNRLGMQSDLLGAAALGIKNVLCLTGDHQ
SFGNHPTAKNVHDLDSIQLVRMVKDMRDDDRFQCGEEIPGGGPRFFIGAAANPFGDPFEF
RPYRLAKKVAAGADFIQTQLIYDIPRFREFMKRVVDMGLHEKVFILAGVGPLKSVGMAKY
MRDQVPGMIVADEYIERMEAAVKHIDKTDKKARAEAWQQEGIRICIEQIQQIREIEGVAG
IHMMAIEWEEAIRPIVEGAGLLPRPAIQ
>A0A2A6RCL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. H4|TrEMBL
MALKNEAQARDIGISFEFFPPKSEEMEGQLWNTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRQAGISIPIVPGIMPIQNLTQLKRFAGACGAIIPGFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIRDFHLYTMNRSPLVSAVLDNLGLSRRAAKNAGAAA
>A0A1F2WSU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Solincola sediminis|TrEMBL
MKSGSNLEKVLEAGHFAVTAEIGPPKSGSARIIEAHGEEIGHAADAFNVTDHQTGVVRLC
SLASCAILRRIGLDTVMQMLCRDANRIRLQGDVLGAVALDVKNILCLSGDHVKFGNHPEA
KGVFDIDSVQLIQTVKIMRDEHKFICGEEIAGEVPLFIGAVENPYADPFEYRTARLAKKV
AAGADFIQTQAVYDVPKFATWMGEVCDAGLDKKTHILAGIIPVKSVGMARYMKKFVSGVE
IPDGMISRLEDAKDVKEEGINVILEIIEQAKEIPGVHGIHVQAVGWEEIVPEIMERAGLL
PRPIL
>A0A2N0KHT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Casp-Chloro-G3|TrEMBL
MPKITDCCFEATGRTCIICDFSPPRSGQPELLNQANIDADFLSVAYNPGRSVRVNAPMLA
AAIKQQVGKDVVFTLATRDMNKLALQSQLLGAQVLGLDNVIVVRGDPFSQRDLPLVKLVD
DYRPTELIAAIAQMNCGVDFRDAKLGAPTDFCIGATVDLGRGIHREARLAHRKVESGAQF
LITQPIFDPAEAFQFQEAYTEASGGQLGVPVFFGLQILEPDGVIFASVPQSVREELAAGR
SGVEMALELHAKFQEARLHNIYLVPPIRRGGARDYAAAQEFLSAAKRI
>A0A3R7VA08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium TMED54|TrEMBL
MNNKLKKKLEKKEFVFTAETSPPDSTEIVDITERISCLKNLADAINVTDGASAKSHLSSL
VVSSIVQSFGIEAIMQITTRDRNRIAIQSDLLGAWTLNIKNILCIYGDQVHTGDQPETKE
VRDLDTLEIAKTADYFKKEKKFPSGRLIKSAPDFFIGGADTPYDIDDKFDCKNLEKKINA
GVNFFQTQYAFDFLTLNKYMNRLNDYGIPEKSFYLIGLGVIKTAKSAKWMNKNLYGINIP
ENIIKRIENSKNQEEEGKKICIELIEQYKGIKGIHGVHLMGYHQEQQIAEVIKYFKN
>A0A163J4B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Absidia glauca|TrEMBL
MSKWDPTFLSCTWGAGGSSQERTMAVCATAQVVHGVETLLHLTCTNMEKQSIDEALLKAK
ETGIQNILALRGDAPRGHEYWTPTENGFTHAVDLVRYIRQHYGDYFCIGVAGYPEGHMDA
ESKQDDLLHLKEKIDAGADFILTQLFYNVDTFVDWVADCRAFGISVPIVPGIMPIPTYQN
FRRMINLCKTQVPDTILQTLDTIKADDQKVKDYGVQLAVDMIKQLHEKHNVCNFHLSTLN
LERSTKLILQDLKLISQDATKQLAHSKLLSAPFSTPQDLDRAENWDEFPNGRYGDSRSPA
FGEVTYSASQSLPTSEASRKWGYPKTVDNITQLFEKYILGQLDSLPWSEDRLQTETDAIR
QALLEINRRGYWTVGSQPSVNGVSSQDPIFGWGPKGGYVYQKAFLEFFVSPHQLDVILKR
FDQDPCVTYYAMNRNGDLLTNVMDEEAQNAVTWGVFPGKEIVQPTLIERANFESWNEEAF
GLWTEWEQNYAPDTDTAKLLKNVGDAFWLVNVVHNDYQLVDGLFNMMLA
>A0A2D0QWB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ictalurus punctatus|TrEMBL
MKMKRVHPLKLSFGEGSNGGPDETERERKRKREGDGDQRGREGIMVNQREENGLLWIKSD
SSGASNSGESSKNSSKESSRCSTPVGESDRGNRLRDKMRRRIESGDCWFSLEFFPPRTAG
GAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCC
KQTKDKLTFYLNKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAVDLVKHIRSEFDDYFD
ICVAGYPTGHPEAESYEEDLRRLKEKVDAGAHFVVTQLFFRAETFLKFLKDCRAIGITCP
ILPGIFPLQGYHSLRQLVKLSKLEVPEEIMKVIEPIKDNDAAIRNYGVQQAVEMCKVLLN
SGDVPGLHFYTLNREVATTEVLRQLGLWAEDPRRPLPWTVSAHPKRKMEDVRPIFWSTRS
KSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLKMWGEELTSEQSV
YEVFTNYITAQPNQNGHKVMCLPWNDDPLAPETNMLKDELEKVNRRGILTINSQPNINGK
PSSDPIVGWGPPGGYVFQKAYLEFFTSNENAKALLKVLKKYEPRVNYHIVNMRGENITNA
PELQPNAVTWGIFPGREIVQPTVVDPVSFMSWKDEAFALWIEQWGKLYEDESPSRMIIQY
IHDNYFLVNLVDNDFPLNSCLWQVIDDMFELLSAPPEPLEENIHSQTDAVSF
>A0A837D3F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora viridis|TrEMBL
MRRVVDRLSSTRCPTFSVEFFPPRNEAEETILWRSIRELEPLDPAYISITYGAGGSSRDG
TIQNIARVATDTTLVPMAHLTAVNHSVAELRNVIGHFAAVGVHNILALRGDPPGDPMGEW
VPHPEGLTYAEELVRLIRELGDFCVGVSAFPYGHPRSPDLETDTRYLLRKLDAGADFAIA
QLFFEAEDFLRLRDRVATGSDALVLPGIMPLTTPRTWRKTIELSGAMPPRWLADRLEPLS
DDPKAFRAEGLDVITELCERLLAEGVPELHFYTFNRSKATRELVDRLGLRSARTKPVLAA
QS
>A0A7Y4AFY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 03-59-1|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELINIADDYWNNGIKNIVALRGD
IPAGGGAPDMYASDLVKLLKSQHDFDISVAAFPEVHPEAKSAQADLINLKRKVDAGADRA
ITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQASRFAAMNNVKVPGWMAQQFN
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPA
>A0A429S1Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC06614|TrEMBL
MTLRQLLDSGIRSFSFEFFPPRSADGARALWEAIRRIEALAPSFVSVTYGAGGSSRDRTV
EVTRRIATQTTLRPIAHLTAVGHSVDELRRVVGQYVEAGVRDVLALRGDPPGDPRGPWVR
HPQGLTYAHELVSLIRELGDFGVGVAAFPERHPRSPDWESEIRHFVAKCRAGADYAVTQM
FFDVEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDATFPTALAARLEAARD
RPAEGHRIGVEHATAMAERLLAEGAPGLHYITLNKSTATLEIHRNVQGSTR
>A0A5J5U4S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium barbadense|TrEMBL
MKVIEKIQSLQEGKAVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNELAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGVKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQYPYGRWGDSRNPS
YGALTDHQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSYCLGKLRSSPWSELDSLQPET
KIIHEQLGNINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGTTDVNAVTWGVFPAKEIVQPTVVDPASFMVWKD
EAFEIWSRAWAALYPEGDPSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>A0A4P7VTJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duncaniella sp. C9|TrEMBL
MRVIDHLQANPGRTAFSFEILPPLKGNSIEKVYNIIDKLRDFDPKYINITSHHSEMIFKE
MPDGSFRPQKMRKRPGSVAIASAIQNKYGITAVPHIICKGFTRDETEYALIDLNFLGVHD
LLLLRGDIKGPEKSDDPTKINRHATDLQAQVNDFNRGIYADGETFEPNATPFSYGMACYP
EKHEEAPNMDSDLYYAKQKVDGGADYLVTQMFFDNSKYFDFVERCRKAGITVPIVPGIKP
VVFANQLNVLPRVFRSDIPEAFASELRKCKDDAEVREVGIEWCIGQCRDLIAHGVPSIHF
YTLMASESVRRIAKEIY
>A0A356UC52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas sp|TrEMBL
MRTSEIFKNKTVLSLEIFPPQRTASVDIIYKTLDELQCLKPDFISVTYGAGGSATNTATL
EIASAIKNHYGIE
>A0A356Z608|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas sp|TrEMBL
MKTAEIFKNKKVLSLEIFPPRRTASINIIYQALDEMKGLNPDFISVTYGAGGSENNQATL
EIAAAIKNHYGIESVAHLPCINLTKREVLHMLEGFKQAGVENILALRGDVNPEIPPQQDF
RYASDLISFIKENGDFNIIGACYPEGHTECRNLVEDIRHLKTKVEAGTNQLITQLFFDNS
YFYSFRERACIAGINVPIEAGIMPVVNKKQIERMVSLCGVKLPQKFVTMMEKYENNPVAM
RDAGIAYAVDQIVDLIAQGVDGIHLYTMNNSYIAQKIYAAIRTLLLAA
>A0A356Z740|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas sp|TrEMBL
ASMPAKMLILVDKYEHYPDDMVKAGIEYASQQVSDLLQNDVPGIHLYTMNKPDQITTIVK
NTRLA
>A0A1F6PJY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Margulisbacteria bacterium GWD2_39_127|TrEMBL
MLYKSRLHKDLLTKKFVVTAELSPPKGVEYNYLLDQAEALSTYVSAFNITDNQRSTMRMS
ALAICHLLESQGFETIFQITCRDRNILALQSDILGASALGIKNILAITGDYPLSGDHPFA
KPVFDIDSVQLVHLLKQVMPGGKDFAGKELKGSPDFIVGVVANHGAQPQEPQLIKLQKKI
NEGAEFIQTQTIYDIDQFLEFLEEVPPAVPVLGGIFPLKSAKIAHFLNDNVPGVSIPETI
LRRMENTKDPYKEGIEIAVETIEAIQPECAGVHFMTMGAVDVIAEILKEVSIDK
>A0A7X5WDD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
ALNQGAVDEERELSRFRYKIEAGADFVVTQPVFEPHALEAFLERAGPLDVPVVAGIWPFI
SLRNAEFLAN
>A0A7V9DCE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MGSPEYMATFARRFAQAGAKFVGGCCGTTPTHIKLISDAIRSISPRQARSYPKAPPAKVN
DLTPNAVSVMPAEDRSKWSSKIARGEFVTSVEVLPPKGCDAHSTLESIRLLKGAGVDAVN
IPDGPRAQTRMSAQATAVLVERDIGIEAVLHYCCRDRNLLGMMSDLLGAAALGLHNLLII
TGDPPKMGPYPDATAVFDIDAIGLTNMANKLNHGLDIGNNPIGKPTEFSIGVGVNPGAVN
LEEEIRRFEWKVEAGAEYAITQPVFDTAQLRSFLDKIAHVRIPIVAGIWPLVSFRNAEFL
HNEVPGVEVTPEILERMRVASENGKEEAREEGIAIARESLLQVRDLIQGVQVSAPFGNVK
YALQVFDVLDLSANADPARANIVV
>A0A7C7KKW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
FFERQVNGLLAGGVDGFILETFADLNEIDCAFTAVRKLGDLPVIAQMTLGQNGKTVYGHT
ASQIAQELTSIGADVIGLNCSVGPAVMLDAIEDMADTTSVPLSAQPNAGLPRTVRDRKIY
MATPEYMAQYACRMVDAGARFVGGCCGTTPDHIKQIRDLVRSDQPRPVMVRVTDVDQERS
ATLDPVPLEACSAWGRKLSRGEPVVSVEVLPPRGWDRNAIVEPAHELKDAGVDSLAIVDG
PRSRSRMGALSAAVIVEQEVGIEAIVHYTCRDRNMLGMISDLLGAAAAGIRNLLVVSGDP
SVHGPYPDMTEVFDIDSIGLTNVVTGLNQGLDPAGNSIGDPTKFVQGVVANPGALDLERE
VTRFRYKVEAGASFVVTQPIFNPESLEEFLDKIHQWKIPVVAGIWPFLNLRNAEFLANEV
PGATVPEKIVDRMRKAQISGDEEALNEGVEIAAEMIDAVRPLVQGFHLSAPSRRVDVALR
VLHEAGVSTNT
>A0A1J5J5H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeum sp. CG2_30_32_3053|TrEMBL
MSLLRENFSRKFTATGEVSPPPCPDKTLFAREVEEMKPLMGRILGVNVVEGPGGRVLMSS
LGASIYMIQHGVEPILQQVVRDKNRVALQNDLISASIFEIENVLSIAGDHPACPASDNPK
SKPVYDMDSTTLIVMLKKLNEGKLWNGKDTNYENKNLNAKTNFFIGTGLSPTSSPLDGEI
YKVKRKLIAGCDFFQTQGVFDIEPIINFLNLYEKTIGEKISDKILVGIVPIWSYGMMKYL
LTLPGIVIGEKFRNDVNEARKKQKETGQKGLIEEIGVNLCVDLVDKIKGLGVKGVHIMPV
GNLHAMKEILDKSGL
>A0A8H3SWK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus tubingensis|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVDQLVDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A6F8ZJS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium R50|TrEMBL
MEPQATELEALLADPRRTLIGDGALGTWLAAAGVAPEDQPWLVLRDPDRILDLHLAYLQA
GARLLETATFLANRVKLAALGREDIDVYTVNRRAAQLARHARDTFGEPAWVLGSLGPLGP
RVVLPGEEAGPADLPYETAYAAYREAVSGLVAGGVDGFIVETLSDLGTARAAVAAIRAES
ALPVVVTFAFSLEGTTLYGLTPEAAAEGVLDLPGGPPAVVGANCGTGPSPLLDAVLRMAP
ILRGHGIRLAAIPNAGQPHLHGQALEYPASPDYMATLVPALKAAGCAVIGGCCGTTPAHI
AAMAAADRREAEPVSGRLELAGGEERPADGGGPQPSPLESRLQAGRFVISVELDPPRGAN
PARLLAAARTLAAAGVDAVNVADSPMARVRMSAMATGRLIREAAGLDIILHFTTRDRNLM
GLESDLLGAYALGMQNILCLTGDPPALGDYAASTAVYDLDSVGLVQVLQRFKAGEDSFGH
SIGQPLRFLAGVGANPNHPDLKEEAVRVRRKLEAGADFIMTQPLYDAGRYLAWLDAVGPL
PVPVLVGVMPLVSYRQAEYLHHEVPGIDIPEAVREAMRQAGQDGARVGMELALAFLEALP
GNLAGIYLVPSFNKVEPLLPLIEAARRRYSRAG
>A0A7C3B7W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineae bacterium|TrEMBL
MAEVSTNGYKSGSNLERLIRAGHFVVTAELGPPKGWQREVIERKAELLRGVVDAVNITDN
QTAIVRMSSIAAGRILVELGLEPIIQMTCRDRNRLGIQSDLLGAVALGIRNVLCLTGDHQ
SFGNHPTAKNVFDIDSIQLVQMVARMRDEGLFQCGEEVEGGRVPLFVGAAANPFGDPFEF
RPYRLAKKVAAGADFIQTQLVYDIPRFKEYMKRVVDMGLHEKVAILAGVGPLKSTGMARY
MRDQVPGMIVADEYVKRMQDAVKGIPKEDRKARREAWRAEGIKICIEQIQQLREIEGVAG
VHIMAIEWEEAVRPIVEGAGLLPRPSVNGQ
>A0A3D4FZC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
PEEVNREATRVARKAAAGRAFVAGAVGPLGIRIEPWGPTGVEEAEALFRRHVAGLCEGGV
DAFVLETFSDPTELSAAYRAIRGLSESPIIAQMTVGEDGKSSYGTEVEHLAAQLDELGVD
VVGLNCSVGPAAMLDAVERMARVTNKPLSAQPNAGVPRTVRDRKIYMASPDYMAAYARRL
IDAGARFVGGCCGTMPEHVKRIKDVVSSLQPIHTHGHTTARVKVVTGHTEDDPLPVVALA
ERSDLGARLAGSEFITSVELLPPHGWDAGEMVAGAHRLREAGVHAVHLVESPHGRSRMAS
VPAGIILTREVGVEPVVQYTCRDRNMPGMLSDMLGAAAAGVRNLLVLSGDPPTQGPYPDA
TLVLDIDSIGLINILTGLNHGLDPGNARIGEPTRFVVGMSTNPAALDPEREVERFMYKVE
AGADFAVTQPLFDVGPLERFLEATKHRPLPILVGVWPLASLKNAEFLANEVPGVVVPASV
VERMRQADRKGPDAARAEGITIAREVVSAARSQVRGVHVSTPGGNVESAIAVLKG
>A0A2H0XUK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Saganbacteria bacterium CG08_land_8_20_14_0_20_45_16|TrEMBL
MKVIEAIIRETPTISFEFFPPKTVEQEAHLFEVLAELEKFKPDFASVTCGALGSNADKTI
FWAKEIKKKFGIEPVAHLTCVSASREAMKKQLDELEKVGVSNVLALRGDPPIGETKFVPS
KNGFSHACELVAFIKEQKPRFCVGVAGYPEGHIEAACLEDDIKHLKMKVEVGADYVITQL
FFNNEDFFRFRDDCSEAGIRVPIIPGIMPITSLKQVKKMTQMCGAIIPQDLLNKLEQADG
DKTAVIEIGVEHALFQARELITRGVHGLHFFVMNQSGPISKVFGQLEI
>A0A3E0R6L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus sp|TrEMBL
MDLTAKKDLREYLRDHLLVGDGAMATQLYRSGVPVGVSFEELCLTNPRLVYDVHKAYYEA
GARLMETNTFGANRDALARYGLEHKVTRINRVAVTIAREAAQDDAYVVGSIGSIIAGRVR
KKVLDEYRDQFEEQAIALLHAGVDGLILETFLDLEELLLAIDVIRPLTGLPLICQLATLD
VGRTRDGYTLTEAFSQLQKAGADIIGLNCRLGPAEILRSFESASVPDGALLSAFPNAGRL
GISDGEYAYKSSPEYFAESALRLREQGVRLLGGCCGTTPDHVRAMAEALKGLAPLPRVNP
SEALTERPSVASYSVRERQKPSIVERVKTGTTIIVEFDPPKDLDTEGFLTGCFELHKAGA
DAITLADNSLANVRMSNMALGAIMKSQYGIDPLVHIACRDRNLIGQQSHLMGLHALGIDQ
VLVVTGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGISFSGRPLKQKAQFIVGAAFNP
NVRHIEAAIKRLEKKVEAGADFIMTQPVYDAESIRLVHDATKHIKIPVFIGIMPLTSSRN
AEFLHNEVPGIKLSDEARERMRRVQGEAARQEGIKMAKELLDVAITYFNGIYLITPFNYY
QMSVELIQYVRQQSQLLKTAAKA
>A0A436KLL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.002.03.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A438B4G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus xishaensis|TrEMBL
MNRIRSSASGRIPFSVEFSPPRDAAAEARLWRAVREFERLNPAFVSMTYGAGGSTRDRTV
RVTGQIAEETTLLPVAHLTAVGHSIDELRAMCGAYADRGISNILALRGDPPGDPLGEWVK
HPEGVEYAEELVRLVRDMGDFHVGVASFPEGHYRAPDLEHDTRYLVQKLRAGAEYSITQM
FFDVEDYLRLRDRVAAHDPEQAEKPIIPEIMPITSLRSARRSLELSGSHLPRALEERLRR
AAGDGPEEDRAAVREVGIEVATEMAERLISEGAPCLHFITLNFARATSEVLANLGTSISA
RV
>A0A2K5XYD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mandrillus leucophaeus|TrEMBL
MVNEARGNGSLNPCLEGSASSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDLCVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDTVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYE
EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVLEDALELLNRPTQNERETEAP
>A0A060QHE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asaia bogorensis|TrEMBL
MSRIAIELIPRDTQSLIEDLATVRQIAPDVTTINLPDLLRLPLRSWEGAALAQGQGYAAI
PHIRAIDIDPDAPLPCAEQEGLREILVIAGDPPPDSTHRIWPNSSADIIARYRREAPHLT
VYAAFDPYRRAPWQELETIQQKRDAGAAGFFTQPLFDQRLFDLCASWLENDQVFWGLSPV
IGPKSRAYWERVNHVVFPSDFEPKLDANIAFARTILEAVRARGESAYLMPLRVPLADYLT
PLRDLLTS
>A0A1H7I825|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas sp. GM95|TrEMBL
MTPVSFEFYPPKTDDQRAQLDRTADKLKKYAPDYVSCTFGAGGSTLSYTSETVRHLKQHH
RFDAAPHLSCVGGNREEIRELLKLYRAIGCKRIVALRGDLPSGMGHAGDLRYASDLIAFI
RAEHGDAFHLEVGAYPETHPQASDALADLKHFKAKVDAGADAAITQYFYNADAYFGFVDA
VRKLGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIAKRMAAYGDDADSIRDFGADVV
AQLCEKLIAGGVPGLHFYTLNLAKPSQLVLKRLGRG
>A0A435U1X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.14.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A1Y5ESK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp. 42_8_T64|TrEMBL
MTNKLTISCEFFPPKTEKGIANLRNVRQQLAPLKPEFFSVTFGAGGSTQDNTLDAVVEIQ
QDKKTTGIDAAPHLSCVGSTADGIRHLLNTYQSHDIRRLVALRGDLPSGMRDPGDFRYAN
ELVEFIRQETGDHFKIEVAAYPEIHPQAQSAQADLANFKRKVEAGADSAITQYFYNIDAY
LHFIDRCQQQNINIPIIPGIMPINNFTQLARFSDGCGAEIPRWLRKQLESFHDDVESLQA
FTLDFLTEFTQKLIDAGVPGLHFYSMNRTDTTLTICQRLSLIN
>A0A2N9KGD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc suionicum|TrEMBL
MTRITDIYKKKSAPVLSFEIFPPKTEDGLHALYKTLQKVNPKETGVDYISVTYGAGGGSN
HKRTKEIAEYIERNCGITALHNLTGINQTPSSLKDNLEKISVAGIENIFALRGDTPTKDY
VNEYYPFAKDLIKEIKKDGRFDIGAAIYPEGHVDNPMTGISVTGVKEKVISGTEFLISQL
FFDNGVFYNMQEALKENYIKVPVSAGILPIISRAQVERITYMIGSSLPARLAKIVHKYEN
QPEALQQAGIEYALEQIHDLLDHGVDGIHLYAMNQPNVLKIMLPEINKHIQSKKLTL
>A0A3M1HS36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineae bacterium|TrEMBL
MNDEYIAGSRLERVLRSGRFAVTAELNPPDSADPQEVYDAAVVLSQVCDAINATDGSGAN
CHMSSMAICALLVRAGYEPVFQMSCRDRNRIAMQGDLLGAVAMGVRNVLCLTGDDVTAGD
QPQAKRVFDLDSIQLLRTITIMRDKGMFLSGRKLTTPPRVFLGAASNPFVPPYEWRPLRL
AKKVEAGAGFVQTQYCFDVPRLRQFMQRVRDLGLHERVYILVGVGPLRSEKAAEFMRTRV
PGVHIPDEIVDRLRKTPKGQKRSEGKRICVEIIQQVREIEGVAGIHVMAYRQEELVAEII
EEAGLLPRPSRLGAPDPRELARPRKWSRA
>A0A2E4N236|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
RSQVQRIASLCGATLPKNLLGQIEDAGDDDEAAKIIGTEQCIAQSQGLIRNGAPGIHYYV
LNRSPQIRRIVRAL
>A0A017HG29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limimaricola hongkongensis DSM 17492|TrEMBL
MTRPAVSFEFFPPKNIEGSFRLWDTVQALAPMGPEFVSVTYGAGGTTRKLTHEAVDAIHK
KTDLRVAAHLTCVDATRAETMEIVDGYAKAGVAEIVALRGDPPKGSGGFRAHPEGFAGSV
ELIEALAKRGNFRIRVGAYPEPHPDAGHALADVEHLKRKFDAGAHSAITQFFFEADTFFR
FRDACVKAGIDAPIIPGILPIENWKGARKFAAMCGTSIPQVVADGFDHAADQAEADLLAT
ALATELCDKLIAGGVEHLHFYTLNKPDLTRDVCHALGITPKPALSEVA
>A0A2G8T8J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia eurypsychrophila|TrEMBL
METNNFSIEFYPPKTAEGADKLRIARAKLATLNPKYFSVTFGAGGSTQQGTLDTVLEILA
EGHDAAPHLSCVGGSREAIRAILAQFKSHGIKRLVALRGDLPSGYGGGSELRYASDLVEF
IRAETGDWFHIEVAAYPEMHPQARSPQDDLQNFARKVQAGANAAITQYFYNADAYFQFVD
NARKLGVDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGMDV
VSELCQQLMEGGAPGLHFYSMNQAGPTTELWKRLTNS
>A0A060QLP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asaia bogorensis|TrEMBL
MTVQSTGKTDGAHNPGGLWRFSLEVTTRDLPSLKGMMSSGASPLEPVTPVMIPHLANDTQ
AARLEAIRTIRTLGLLPVPHFSARRLASKAACETLLAQMVAEAGIERCFIIAGDPSEPAG
PFADSAALLATGLFEKAGIGVVGIGGYPEGHPLMTPEQGWTVLEHKCRDIEARGMTPEIV
TQFGFDAQAITTWLMRLRERGITCHIRIGVPGPASIASLLRFAARCGVGASASVLSRYGI
SLGKLLGSAGPDQLITQLEEQLADPHGPVSLHFYPFGNLGRTMDWIGQRIGKG
>E6WYS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratifractor salsuginis (strain DSM 16511 / JCM 12458 / E9I37-1)|TrEMBL
MFDTFCQNLQGTSPFITVEITPPHGASMDPILEAIEASGLVQKKISGFSVTDNPLARLKM
SAILSAIRVQQRFGKPVIATMSMRDRNKLSLQSSLLGANDFDIRLILALTGDPAKFSDQP
EVKGVLERDSTLLLSIIYRLNNGYDYSGQELDPKPRPIYPFAVSNAYAKDMKQLMKRMVK
KLDYGARAIITQPVFDLDNARELLEIFEEAKGKSIRETAKEARLILGQFPIVRARTATFI
DDKVPGIHVPKRIIDEMNLAAMDGVEKEQEVGFTLSKRIFDEIMALHPKVHLMTHNRFEL
CAKLIER
>A0A7Y6Q563|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. HO-A22|TrEMBL
MTAQTLYPAERGNLRLSFEYFPPKTDEMEAQLFQTAEDLSVFCPAFVTVTYGAGGSTKTR
SLTTVKRMIEEKGFANTAAHLTCVGAPKSEVDTVIDEFLSFGVRHFVALRGDPQGGIGST
YAPFPGGYESSSDLVRALRDRGDVEISVSSYPEKHPESPDVDADIDMLKRKVDAGATRAL
TQFFFDNDDFERYLERVRRAGIDIPIVPGILPINNLAQVQKFAGLCGASVPEVIVTRLAH
LEDQPTERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFERADEMAQS
EHVALKAVAGAAA
>A0A7V4B0W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MSTAFKQALENGKFVVTSEIGPPKGVNLDPMKHHIELLKDRVDALNVTDNQSSVMRFPSL
GGTLNVKELGAEPILQMTCRDRNRLALQADLLFAYSRGVRNVLCLTGDAVPVGDHKQAKA
VFDLESVQLLHTVRHLETGKDLGGNDLDGPVEFCAGAIVTPEADPLEPQLLKFEKKIQAG
AEFFQTQAIYDLNNFRAFMDFARQFEVKILAGVVLLVSARMARYMNANVPGIFVPDELIA
ELEAAPKGEALKTGIRIAGRMIRELREEKICDGVHIMAIGKEEVVPDILAAAGM
>A0A7V9I9B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexia bacterium|TrEMBL
MRSPFLDRAERGPVLADGAVGTLLYERGVPYGGCFDVLNLKDRALVGSVHRDYLAAGAEL
ITTNTFGANRVRLAEFGLQDAVRDINLQGAKVARDAREVSGRTAFVAGSVGPILRPLTEE
HRESEGQLRAAFREQAEALLEGGADVIALETFSDLDEIRIAIEAARAVCELPIIAQMTFG
DDGYTLEGHAPEEVAERLQFFGADLVGINCSVGPQNTLDTVQRMLAVGVRRVAAQPNAGL
PSRQGQHFVYISGPAYFADYAKKFVDAGVGLVGGCCGTTPAHIAAMAAALNEARPLVRPS
VQQSFPPPAPKTEASRGEVAPTRLAEAIRQGEFIVSVELDPPKGLNPTKVLDGAQMLAER
GVRFVNVADSPMARVRMSALSMAKLIQDCADVETIIHFTTRDRNLMALQSELIGAHAMGV
RNVLALTGDPPTLGDYPDATGVWDVDSIGLVGTLSRLNAGVDRAGRAVGAHANFCIGCAV
DPTAEDLEEHIDRFWRKLEAGAHFVMSQPLYDIDALHTFLDRVGPLPVPFLLGVLPLQSF
KHADYMHNEVPGIRVPEGVRRAMHDAGSSGMSEGIRLAQHFVDAAQDRVQGIYLMPSFGR
YEQCAEVIDALDSSRRPGSAQSSNPVDQHVKAAPVRSADRS
>A0A7V2YZU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKQSPVVFDGAMGTMIYSKGVFLNVCYDELCLSNPGLIQEIHREYVAAGADVIETNSFGA
NRIKLRQFGLAENVEAINRAAVRLAREAAGEQAWVAGSIGPCLKTGQMLKGENKPEIVAA
FREQMSALAGAGASLLLLETFCDLNELRLAAQTAREFALPVFASFTVNDAGETALGAQAE
SVVAALNDAASVDAIGLNCGAGPAGVYEVLERVLPLTQKPFLAMPNAGVPREVEGRMLYL
ANPEYFTEYAKRFIELGVRAVGGCCGTTPAHIRVMARAVKSLSGARRRVEAAARASREEA
RVAAVPTAAKSRLANLISRGRRVTSVELLPPKSSDLAPFLAKARACHLRGIDAINIPDGP
RASARVSPMVAAIAVKNEIGIEPVLHYCCRDRNLIGMQSDLLGGFAAGLRNFLIITGDPP
KLGEYPDATGVFDVDAIGLTRVVHNLNHGCDVGGATIDPPTAIFIGVGANPTAIEPRREM
DRFMAKIDAGAEFAITQPVFDADALFRFMDQAAAAGRCLPIVAGVWPLTSYKNAEFMRNE
VPGVSVPAAVMDRMSRCQTKEDGLKAGVEIARAICERIAPRVAGFQISAPFGRVELAIET
VEGL
>A0A7X8M8X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MAEAEKPRSCSKADALLSRLEQSVLVCDGAMGTLLYQRGIFINRCYDELNLSAPDLVLDI
HRQYAAARADILETNTFGANRLKLKAHGLESEVERINQAGVRLARQAVGPEGLVAGSIGP
LGVPLAPLGIVSEEEARSIFRQQALALLNEGVDLFILETFSDLNELTLALQCLRELSDLA
LVAQMSFDAEGVTKYGLSPEAVVPGLIAAGANVIGANCSVGPQMMLEVVERLAHSGGRFL
SAQPNAGNPRMVDGRLIYLSTPEYHAEFARRFIAAGVQIVGGCCGTTPEHIKAIANAVAA
VRPRRIRPTAARPGKNTLQVETVPREEKSALAARLGKKFVLSVEVLAPRGVDVAPVLNGV
RKLVGFGVDAINIPDGPRASSRMSPSALAQLIERSLPVETILHYCCRDRNLLGMQSDLLG
HYALGLRNILAITGDPPKLGDYPDATAVFDVDSIGLTRMINALNQGYDLAGNAIGRATGW
HIGVGANPGALDLDLEIRRLYQKAEAGAEYVLTQPVFDIAQMERFFQRISDLRLPVLAGV
MPLMNFRTIEFLNNEVPGVTVPEAVVRRMDHLSRVFLQV
>A0A533RW17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
NRNQIESQLYAMDRANVRSLLVMTGDYVYTGFQGRPKPVFDIDVMHVVQLIKEMNAGLEY
KGMKGTIKHQPSDFFAGVAASPFKRTEAEQMLQYFKLKKKIEAGGEFVVSQLGYDVRKIH
ELIQFIRQQGWDLPVVGNIYLLPLGAAKLMNRNGLPGCVAPDKLVADLAKEAEAPDKGKE
ARLVRAAKMYGFLKGMGYDGVHIGGHGMTYDQLEFILDKGEEYSKNWMDYIHEFDYPIPG
GYYYYEKDEKTGLNTDRPVERKGRPLDTPVEFTYRLSTFMHNMMLEPGTPFWGPMRAIAK
AVDGTSMEKPYHFFEHMAKVALFDCKDCGDCALTDVGYVCPMSNCPKNQRNGACGGSWDG
WCEVYGTKKKCAWVRAYARLKDGGKENKLREYIVPPANWDFYQKASWITFYLGMDHTAKR
IGVEPVEKKK
>A0A1D7XM71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium taeniosporum|TrEMBL
MNIKNLFRDKKAVFSFEIFPPKTTSSIQTIYNTLEDLKGLSPDYISVTYGAGGSVKNSKT
IELSSLIKNKYGIEAVSHLTCINLDKKDVKYYLREFEKNNIENILALRGDIDIGSKIIGE
LDHANELIKYINDNGNFNIAAACYPEGHIEHKGLYREIESMKRKEYSGASYFISQLFFDN
NLYYNFQDEVRAANINLPIEAGIMPVTNKKQIERILSLSGASFPNKFKKIIDKYEHNPEA
LRDAGIAYAVEQIVDLISTGVDGIHLYIMNNPYIAQKITKSIESILLTVNKI
>A0A1Q5XI33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. P3E|TrEMBL
MTLLLNKSQLQADSFAVTAELIPPRDWNPRPLVEQAVRYRGYVDAVDLSDNLLAIARLSP
VVGAFFVRQVGMEPIVQINLRDRNRMAIQSDLMGLAAIGVKNITILGGYPAKVGTEPNAK
EVYDLETMELVRYARKFADEGLLFDGTRMQEPPKFTIGTVENIAGKPIKELIDRLESKVE
NGTDFVRTQLVFDMDLIGEWMEEVRRRGLHERVTIMASILPLRDAEHVGTALRIPGIVIP
DSFHARLSASESKEEGLLIAAELIKKLRQIEGIHGIHIRPIGGAEDSVNKVVQYAGLMSS
PSVSASA
>A0A0A1SLS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Torrubiella hemipterigena|TrEMBL
MEKITDKIAALPADGEYFSLEFFPPKTAMGFANLRDRLQRMEQALRPLFVNVTWGAGGST
ADKSLELAELCQRQLGMTTCLHLTCTNMSQTLIDKALEDAKALGIRNILALRGDPPRDDE
YRDQDAPAQEANTDTFVWAVDLVKYIRRKYGDHFCIGVAAYPEGHADGSHPIGQSLEHDL
PYLVDKVQAGADFIMTQLFFDTDAYDKFEQTLRDHPSGAFKTIPILPGLMPIQSYAMIKR
TAKLSHASMPAAIMDRLNQVRGDDEAVKQVGVEILSEMVEKIRDTKQRTPGPKGFHFYTL
NLEKSVTFILERTHLIPDTSDDEVAIADGPIPTPLLQINGGIPLRNRSHRSSSRRQSSVG
SDPHNRVIVSGRAVSRPEWEASGQEAGVRAQDINSRANTLAISEGEGALGREATWDDFPN
GRFGDSRSPAYGEIDGYGVSLHMSVTQAVSLWGHPAAVSDINDMFVNHVTGKLNAIPWSE
EELMPESSAITAHLKDLNSKGWWSVASQPAINSASSRDSTFGWGPPNGFVFQKAFVEFFL
PAADWETLKAKLLSADVHEHVCFYAANAAGDFVTSDITGGARTEGASTNAVTWGVFPGKE
IVTPTIIEEVSFKAWSEEAFGIWGEWARVYGKGSPSEKLLSGIRNDYWLVNVIHHEFVDS
EGLWALLLD
>A0A0P0IW62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Ndbn-20|TrEMBL
MKLALAAQDSPVLDLVRSFSLEMTAKDIDSLSEAAPLIPAGTPISVTYLPGEEMPARVAA
AKAVKALGFVPVPHISARRVLSRDDLADFLAILDDQVGIERAFVIAGDPPAPMGPFEDAL
AVIRSGMLDAAGIRTVGISGYPEGHPDIDKPKLARAMQDKLAALAEQGKEAEIMTQFAFD
ADAILVWLERIRQDGVVAPVRLGVPGPASVKKLVRFAARCGVGASAKVMLKYGTSITKLF
NTAGPERLIEDLAARLDPARHGQVMLHFYPFGALLDTARFIDTNYPAAGR
>A0A258R759|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium 28-61-11|TrEMBL
MSQRTFSFEFFPPKTAEGAEKLRATRAQLAQLKPKFFSVTFGAGGSTRDRTLETVREIQA
SGSEAAPHLSCIGSTQDNIREILNEYKSQGIRHLVALRGDLPSGTMDAGEFNYANELVSF
IRAETGDWFEIEVAAYPEIHPQARSWTDDLANFKRKVDAGADSAITQYFFNADAYFRFVD
EARALGVAIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLASIGAPGLHF
YTMNQAGPSTTIWQRLGL
>B0RV90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. campestris (strain B100)|TrEMBL
MAARSAGPAAMTHLSFEFYPPKTDDQRAQLDRTAAKLKAYAPEYVSCTFGAGGSTLSYTS
ETVRHLKQKHGFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDL
RYASDLIAFIRAEHGDAFRIEVGAYPETHPQAIDADSDLKYFKAKVDAGADAAITQYFYN
ADAYFHFRDAAQRLGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDAD
AVRAFGAEVVAGLCERLIAGGVPALHFYTLNLAKPTTQVLQLLGR
>A0A350D8H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKAGSNLEKILKSREFAVTAELGPPKNADRDVIEKKVKILKGFADAVNVTDNQTAIVRMS
SMAACSILVQLGLEPIMQMVTRDRNRIAIQSDILGASALGIKNLLCLTGDHQKSGNHPQS
KNVYDLDSVQLVAAVKKMRDDKRFINGEEIKEHEPRIFIGAAESPFADPTEIRTLRLAKK
IRAGADFIQTQAIYDLDRFEEWMKEVREKGLDKEVHILVGLIPLKSFGMAKYMNTHVAGV
NVPEDLMKRIKEAEDPKREGIKICVEAIDRLKRIEGVHGVHIMAIEWEDAVPTIVEEANL
LPRPKI
>A0A0X8L3N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. PAMC 26561|TrEMBL
MKPIELSFEFFPPKTLEGIEKLRATGAQLKTLNPKFVSVTFGAGGSTQQGTLDTVLEMMK
QGLEAAPHLSCIGSSKDSLRGILGGYREHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFNIEVAAYPEYHPQARSPKSDLDNFVRKVQAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPKWIARRLESFGDDKESIRAFGLDV
VTGLCERLVKEGAPGLHFYTLNGAAASKTIWERLKLQGR
>B6BQ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pelagibacter sp. HTCC7211|TrEMBL
MTAFSNKIMIEKKMNFSLEIGPKTDLETLPPVKDVYVTMLPGGDYKETSDQSIELVKKGF
NPVPHFPARSIENDSELKDYVSRCKDGGVKQALIIGGGREPMGKFDSSFQLLETGYFENM
KIGIAGHPEGSPDISDTDLDKAMMDKKPYADYIVTQWLLDPQPIIDFISKQSVPVHVGIT
GPLKISSLIKFANIVGAKNSLNFLKSNFSKALDLLKPKDPNDLIGKVKSHTDNFHIYTFG
GLKETNKWLKENSYV
>A0A1F9NN92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium GWB2_56_26|TrEMBL
MKTESRLEKVLAAGHLAVTSECGPPRGCQPAHLIEKAKYLDGIVDAVNVTDNQTAMVRMS
SLAASFIIKQQGLNPLFQVTCRDRNRLAMQADIIGAYSMGIDTMLCLSGDHTKFGDHPMA
MNVHDIDSIQMIQMVKDMRDKGIFQGGAEIKGAPKMFIGAAANPFADPFELRVMRLAKKI
AAGADFIQTQCIFNVPKFEKWMEGVREKGLHKKCYILAGVTPCKSLGAAKYMANRVPGMD
VPKEIVDRMASVPKEKQAEEGVTICVETIEKLKKIEGVSGIHIMAIEWEEKVQEICERAG
LLPRPQV
>A0A497MER8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MAERVYSNLMRELKAGKFVFTGELEPGKEGSIEGTIEAARKLLGHVTACNVTDNPQSFGC
VDSLAAAHKIQAETGMECICQLRCSDKNRLALLSSVLAAGVLGIKNILAITGDYVSLGDT
PDVKPVYDLDATLLTRMIRRVVDEGKDLRGGEIRNPPKLHVGVAANPGSAFLDMEVYKLK
RKVLAGAEFVQTQVVYLPEVVDNFFAKVKEVGVEIPILIGIFPAKSYAEAKFFHEQVSGV
TVPEDYLAKLKETKEIKDKEKRKERIDQINIDYFTGFLEHLKSTPAAGCHIMAVGYPEII
PELKKVVG
>A0A0E1XK13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus MN8|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A842ZIP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MDKITDKIAALPPDAMYTSLEFFPPKTDMGFSNLRDRLDRMERALRPLFVSVTWGAGGST
AQKSLDLAEICQRSLGLTTCLHLTCTNMSRSLVDKALEDAKALGIRNILALRGDPPRPDE
YRDPDDAAGNEPHDFSWAIDLVRYIRKNHGDYFCLGVAAYPQGHADGSHPVEQSVEHDLP
YLVEKVKAGADFIITQLFFDTDDYDSFERRLRDHPSGVFKTIPIIPGLMPIQSYQMIKRT
TKLSHATIPDDIMRRLTEVRGDDEKVKSVGVDILSEIIEDLKKIKGRTPGPRGFHFYTLN
LEKVVSFTL
>A0A524A316|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MGKKRPAYSNLMKEIEAGRFVLTGELEPEKTTGLEEVLASARAMKPYVVAANVTDNPLAM
AFMNSLVPSYIVQRDVGLETVYQMVIRDRNRLALTSDVLAAAHLGIKNILAISGDHTVLG
DNKGGLPVYDLDSAQFVYLLHKMIDEGTDLEGNEIHGEVPINVAIAANPNANPLEPEILK
VGRKVKLGTDFIQTQTMFDIDLTKEFLKETEKFNCPTLVGVFPLKSFGIADFFDKYIPGV
SVPKDLLDSLRKCKEEPDKEKRKPLYDEVNMEFFAPFIKEIRKTTKAAGVHVMAVLYERI
LEPLLAETM
>A0A844F7E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium scindens (strain JCM 10418 / VPI 12708)|TrEMBL
MKIRDILKDNSPHVSFEVFPPKTDAGYEGVRAATEKIAALRPSFISVTYGAGGGTSRNTV
RIASQIKNDLGVTSLAHLTCVSSTKDEVHGVIGQLKEQGIENILALRGDIPADGEFPLPN
HYRYACELVEDIKSQGDFCIGAACYPEGHVEAAHKKDDIMNLKHKVDCGVDFLTTQMFFD
NNILYNFLYRIREKGITVPVLPGIMPVTSAKQMKRICDLSGTVLPERFRAILDRFGEDPD
AMKQAGIIYATDQIIDLIANGLNHIHIYSMNKPEVAEAIIGNLSTIIKV
>A0A7S9RFW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter concisus|TrEMBL
MLKEKILNKEKGLVLYGLTPPKAEFEEAKLREISERWTGRINDIKADGLVLYEVQDESER
NDSERTFEFSGTLSPEIYYKKYLNIATPSIFYRVASGYSEDEFRAALKAQSSNLNVLVGA
TSSTQKVRLNLARAYEIASKFKELAVGGVCIAERHGKKGDEPQRMREKIAAGAKFFISQA
IFDAQLARKFLEDCAAIKISEPIFLTFSTAGNPKTLEFIKWLGVSVPSSVEERLSLSSDY
LASSCEIIKEIWCELKKFGDENGLNLSINIESVMAKRAEIEASLELTKSIRELV
>A0A497M9T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MFRELIKEKDVPITYELWSPRGCMVNQHFEAVSRFKDKLDAVNIPDNPLATLRVSSIAYS
KIVMDRLKIDVIPHINCRDRNSLALQSDILGAHLLGIRNLFIVGGDKPAGKTVKTKGVWA
VTSTELCKIVKHLNEGFARSNDDLVEIYGKTDFFVGGAIVFDRKNEVEIISRKIEAGFDF
FQSQIVFSHEKVLNFFREAEERGVTINKPVLVGLSPQPSEKALNKLVRFLRVEMPKSSAD
RLRRSGDFAGEMLSVCLEVADELKSALSPKYKIGFHIMPLGYDDLGRKLVEGLRG
>A0A2P2DG55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira ellinghausenii|TrEMBL
MHISEILGKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEETGLTIVSHLTCVGSTKEEIGEILKRYQKSGIHNIMALRGDPPKGQNEFQKT
ENGFEYAGELVGFIKGNYPNMGIGVAGFPEGHPSTPNRLKEIEYLKWKVDQGADYICTQL
FFNNDYFYDFVERCEIAGIKVPIIAGIMPITSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDTYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRKIYESLGIRNFDRIV
>A0A4P5UEH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonadaceae bacterium|TrEMBL
MESQKKFAPTFSFEFFPPQTPEGVERLRAARRQLAQLNPKFFSVTFGAGGSTRYRTLETV
LEIQAEGHAAAPHLSCIGSTAENIRTMLERYRDQGIRHIVALRGDLPSGMAQAGEFRYAN
ELVMFIRREFGDAFHIEVAGYPEYHPQSRSSQEDLQNFKRKVDSGANSAITQYFYNADAY
FNFIEACEAEGICIPIVPGIMPINKFSQLARFSDTCGAEIPRWIRKRLESYGDDSASIRA
FGLDVVTDLCDRLLKGGAPGLHFYTLNSAGLTSTIWQRLGL
>A0A090AQG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Tachikawaea gelatinosa|TrEMBL
MNSFALHKNKVKSFNKYLLEINKSINISFEFFPPVNQKMEDMFWISINKLNTLSPNFISI
TYNNKIGKNNRTHSIVKKLKNHKKINNIAPHLTCINFNREELLNIAHNYWNQGIRHIVAL
RGDQNEHSINSKMYACDLVSLLKEVGNFEISVAAYPESHINSKNAYQDLIYLKRKIDCGA
NRAITQFFFDTDIYLRFRDECAAIGINVDIVPGILPILNFQQLCKFANFTKVHIPKWIYS
SFEKLEKEPKIEKIISANIAIEMIKILSKEGVKNFHFYTLNRSEITYAICRIINFQSY
>A0A1B8HQS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morganella psychrotolerans|TrEMBL
MSFLHVDQHEALNQNLAELAGRVEVSFEFFPPGTPEMENTLWQSIDRLSVLKPKFVSVTY
GANSGERDRTHSVIKGIKEKTGLIAVPHLTCIDATRDELKTIAKDYWDNGIRHIVALRGD
LPDNSRKPDMYAADLVSLLKSVADFDISVAAYPEVHPEARSAQADLINLKKKIDAGADRA
ITQFFFDVSTYLRFRDRCAAAGIDVEIVPGILPVSNFKQLQRFAGMTNVRIPGWLGNMFE
GLDDDPESRKLVGASVAMEMVKILSREGVKNFHFYTLNRAELTYAICHTLGVRPAVACVA
>A0A2D4ZPG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinovum sp|TrEMBL
MSTPEISFEFFPPASLKDSFRLWNTINALEGFQPKFISITYGTGNKPRALTQDLVETLLE
HKDLTVAAHLTCVDMSAESTLNLVRSLAAKGLKDIVALRGDPAPDHGGAFRPHPLGYQTS
CEMIAALKNLGGFKIRAAAYPQGHSESRSQAADLDWLKRKFEAGADEAITQFFFEADDFL
RFRDACVKSGIDAPIIPGILPIENWTKTRNFAKKCGVSVPLWLEEAFERATRDGRHDLLS
TAIGTELCDTLRSEGVDTLHFYTLNRPELTRDICLALGLTAKPSLKAVA
>A0A1Y2J6R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trametes coccinea BRFM310|TrEMBL
MKFIDKIAKHDKRKLFYAFEFFPPKTDQGFENLVARIGRMVGLNPLAISVTWGAGGSTKD
RSLDLAALTQLEYGVDTILHLTCTNMVQGSVDSALRAAKERGVENILALRGDPPRGKEHW
EPTDPRFQHGVDLVRYIKTTPEFAHFCVGVAAYPDGHPDRDTDEDGELEYLKQKVDAGAD
FIVTQLFYDIDNFLRWYGKVRAKGITVPIIPGIMPIQTYASFLRMTKLCATRVPASLMHD
LMPIRHDDQKVKDYGVKLAVDMIRQMQRGGIEGIHFCTLNLERSVTRVLESLGLAGNIPT
LANRLIADIPSPPERTVTPHTAADQATKELVSAPHPEPDAGKGEINSAVDWDDFPNGRFG
DFKSPAYGETDRWGSSALQSNLAPSHWGHPRTLDDLTTMFLRYLHSKIPTTPFSATPLSP
ESLMIFPHLEKLTRRGWWTVGSQPAVNGVPSTDDVVGWGPKGGYVYQKCFVEFLVEEEDV
RRIVDKVQKEGGGWINYFAGNAKGELLTNVPEGGRNAVTWGVFPGQEIAQTTIIEKESFL
SWKDEAFSIWSEWASYYPPDSPERTLLEDVRDRRWLVSLVHHDYVDPAALWTFLFKGANP
LL
>A0A5C5VMG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastopirellula retiformator|TrEMBL
MNLADYYSPGRLGLSFELFPPKTDKGDASLMLHVEKLVKFKPDYITCTYGAGGSTRGKTL
DIVEKVKQVFGVPVASHLTLVESTVADLRLYLAEAERRGVDYIVALRGDPPQGQKKFTPA
AKGLSYASELVELIKDEFQEFGVAVAGYPEKHLEAESLEIDIDRLKHKVDSGADIIITQL
FYRNQDFYEFREKCVANGINVPIVPGIFPIVNGAQIQRIGSMCGAKIPRVLVEALQKKPD
DTEYHMQVGVEYATRQIQELTEAGIPGLHFYVLNRSEATAAILANVRYAKSRS
>A0A6H9IYX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. BPN334|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGILISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7C0XM29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
PRMFIGAAANPFGDPFELRVVRLAKKIAAGADFIQTQCIYDMKRFRQWMQQVQDKGLHQK
VHILAGLTPLRSVRMAQYMKQSVAGVTIPDEIIQRMAQAKDPAEEGVKICVEQIEELKEI
EGIAGIHLMAVAWEKIVPVIVERAGLMPRPSV
>A0A1E5QBG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetovibrio blakemorei|TrEMBL
MSSPLPKDANVSFEFFPPKTEKMEESLWACIERLAPLKPQYVSVTYGAGGSTRERTHATV
TRIRRETNLEPAAHLTCVGATRDEIDAIARQYWADGIRHIVALRGDPVDGIETAYVPHPG
GYAYGEDLVKGLKAIADFEISVAAYPEVHPQAKSAEADLDNLKRKIDAGATRAITQSFFD
VDVFLNFVDRARQAGITVPIVPGILPVTNFKRIQEFSGQTGTSVPQWMADLFAGLDDDPE
TRKLVAASVAAEQCRVLYANGIKDFHFYTLNRADLTYAICHILGVRPNVQK
>A0A2S2E4G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saliniradius amylolyticus|TrEMBL
MSKYADRQFSFEFFPPKTETGENKLKASLERLQRYSPEYVSVTFGAGGSTRERTLETVDW
IKQNGRVDVAPHLSCIGSMEKDIEGILRQYREMGIKRIVALRGDIPEHGDAFIEGGFRYA
NELVGFIREFGGFEIHVGCYPEFHPESSSAKVDLDNFARKVKAGADEAITQYFFNNDAYY
YFIDEIQKRGVEVPVHVGLMPITNYNQIRRFSDICGAEIPRWLSERMKDLGDDTQAQEDL
GVEFATRQAEELLEQGAPGIHFYTLNNAGPTERIWRNLGLVDSTNHNDRT
>A0A3N2CXV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmoricola aurantiacus|TrEMBL
MSGTPARIGDLLGSGQRSFSFEFFPPKDEAGEDVLWRSISELEPLQPSFVSVTYGAGGTT
RDRTLAITARIAQETSLLPMAHLTCVGHTTAELLDILAALRGSGVGNVLALRGDPPGGPG
TAFEPTPGGVDYANELVELVRRSSDLCVGVAAFPEGHRDAATLDDDVAVLRAKQDAGAEF
AVTEMVLRASDYLGLVERAGAAGVTIPIVPGIMPILGITSMTKMVELSGRDIPEEVRSRI
EPLADDPAAVRSEGIAIATELCDDLLAEGSPGLHFYTLNRSKATREIWSALSLSA
>A0A4P7CE10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora xinjiangensis|TrEMBL
MRTVVERLSSARCPTFSVEFFPPRDDADEAVLWRSIRELEPLDPAYVSITYGAGGTSREG
TIRNIARVATDTTLVPMAHLTAVNHSVAELRHVIGHFAAVGVRNILALRGDPPGDPMGEW
VPHPKGLRYAEELVRLVRELGDFCVGVSAFPYGHPRSTDLDTDTRYLVRKLDAGADFAIA
QLFFEAGDFLRLRDRVAAAGNDALMLPGIMPLTTPRTWRKTIELSGATPPSWLVERLEPL
SDDPKAFRAEGLDVITELCEHLLAEGVPELHFYTFNRSKATRELVDRLGLRTPRVEPASA
GS
>A0A395RYZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium longipes|TrEMBL
MHIKDMLSDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WEAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELEWAPSAERP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKTIQDIAQLFVSYLTNKVESLPWSESPLTTEADEIRDDLIE
LNKRGLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPAVFDKMISRIESHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVDDLTTPATPLSEPI
SNGAVDTEPIANGATATAVAN
>A0A353GXM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MKIKDIYIQKKAVLSFEIFPPKPDYPVDSVFHTLEGLKDLGPDFISVTYGAGGSNRARTI
EIASRVKHDYQMESQAHLTCIGHSPAELEKIIDEIKEHDIENILALRGDPPRDQPNYRPQ
EGYYLDSIDLVRHIRRKGGFCIGAAAYPEGHSQSARWDQDWLRLRDKVMEGVDFLLTQMF
FDNRVFYNFAENMFRLGVKVPISPGIMPILNINQIKRMINLSGASIPSKLLLMFDKYGDN
SSDFEKAGIEYAINQIDDLLENGVAGIHLCTMNKVEQTRMIVQNSKLRSRP
>A0A2R7P416|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. HMWF018|TrEMBL
MNAAHAQGTGFPVSFEFFPPKTPEGADKLRVARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILSEGVGAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHLEVAAYPEVHPQARSPEADLQAYVTKVRAGADSAITQYFYNSD
AYFRFVEDAHQLGADVPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A2N7PSK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesoaciditoga sp|TrEMBL
MKVIDLVKKQRILSIEVIPPDRGKDIDEIFSAIDEIMEFSPSFINVTRHAPEIDYLEFGD
RIIKVPKIKRPGTVGVSAAIKNRYNVDVVPHVLCLGMNKFEIEDMLIDLKYLEIENLFVI
RGELENRKEMASEKDGYNHADELVAQISKMNKGIYLYPVENPKSTNFCIGVAGYPEKHYE
ALNLEEDLKYLKKKIDAGADYVITQMFFDFEIYKNFVEKAREIGINVPIIPGIKPIVQFK
SMVKIPSTFFVTIPKEFASAMQEAKTPQEEFKTGTRYMSKLVDKLLNYGVPGIHIFTMGK
GKSTKALLEAVYK
>A0A0K0GHP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzae (strain PXO99A)|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYADDADAVRAFGADVV
AALCERLMAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A330F4Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. SM1B|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADNFDADIKRFCEKAHAGANTALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A7C6W1Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium|TrEMBL
MQSQLRYPPVFSCEFFPPNTDEGMRKLFAAREELMRMRPAFFSVTYGAGGSTRERTFQAI
KAIQMHSGVDAAPHLTCVASTRAGIREILDTYRAQGIHRIVALRGDLPSGMREFGEFRYA
NELVAFIRTETGDHFHIEVAAYPEFHPQAPNTERDLFNFKRKVEAGANSAITQYFYNPDS
YFRFVDDCEKLGLDLPIVPGIMPITNFTQLARFSDNCGAEIPRWIRKRLESCGDDRDAIR
AYGLDVVTDLCRRLLDGGAPGLHFYTMNQAGPTLAICERLGLTRG
>A0A537KNK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrabacteria group bacterium ANGP1|TrEMBL
MGVGVCHSGRGSSDGAHGVGSLAGPLCGSRSGRAAARPSRSGVTMNQPAYPNHVREALSS
GRFMLSIEVATADAIRPVLALARQIRNDPRIDAIALTDRSRSDHDHDPIVVGHRVAEVSG
KMPIVHWAGKDRALTTLEADVARANALGLDTLLLVTGDKVRQQPADRPVRYLDSVNALYA
ARRRAPELLLAAAVSPFKYREEELINQYLKAAKKLRAGANLLMSQIGWDPRKFEELRWFL
ERRGYRAPLVAELLLLTPARSRRIRRIGLPGVTITDGLAQRLEEEASSPDGGRAAAFRRL
ALQMTSLRDLGYAGAQVSGLETYTGIMHLLDDIETVIREYPTSEARRRAWLELLMLKDGR
TAQVAPAGGVDLRASARVEPAAPNPGRGGPRTGERARFRVMDLIDHLLFQEGSFGARALA
PALRRLDARSGPGALLLRLERVIKEPLVGCQSCGFCRLPHTAYVCPETCPKGLANGPCGG
TKDNVCEFGDRECIHNQIYRVSKQAGLLANLEEVLMPPVPEAAWGSCSWVTHFQGEGPKV
KRLPAPGTQGKPSDASQSL
>A0A2M9NCK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. GM1FR|TrEMBL
MKADLRKVMQERVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRSYRDAGTEI
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQISALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GEFRYGATPEYFGQTAVQFAELGARIIGGCCGTTPDHITAMKEALADYVPSPILEPDPSE
SKPRIVLHENVDERSGRGGQPTIVDLVKHRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALSINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLEKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A7W4NRD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconacetobacter sacchari|TrEMBL
MTIDPEAMLAGTPRACLRMRDAPPPVLSFEFVPPRTDAMAQRLWHCIRRLAPLSPRFVSV
TYGAGGSAQASTRATIARLKRETSLAPAAHLTCIGATREHIDDIARAYWQAGVRHIVALR
GDPPPGAGHAPHPGGYAYASDLVAGLRRIADFEISVAAYPETHPAASSPEADLDNLKRKL
DAGATRAITQYFFDAATYLRLRDRCLAAGITAPIVPGIMPISTYDQVARFSAICGVTVPA
WLTHLFEDTSRNPELRRIVAGVVAVELVRTLQAHGINEFHISTMNRPDLPYAIAHMLGAR
PTGEDAAAG
>A0A4Q9TLS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. OL1|TrEMBL
MGLLERLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESKVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLDEI
LATIEEQASVLLAGNPDGLLLETYYDFEELTATLKMLREKTKLPIIAQVSMHEPGVLQNG
MSLNNALHELEALGADIVGVNCRLGPHHTILAFEGVELPNKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVQEKHAKPEKIEI
VREAEPTKYEPLHEKVKRERSVIVELDTPRHLEIDGFLEGAKQLYDAGADVVMMADNSLA
SPRISNIAMGALLKSTHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDVLAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNGGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVTR
LEKKIEHGADYFISQPVYTKEKIVEIYEATKHLQAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSEDALTRMKACGEDKERATLEGIAIAKELVEVATQYFNGIYLITPFLRYDVTLELMKY
IEQLDEQKKGVSIHG
>A0A7Y8III0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MSLEESLKKKRFIVTSEVQPPIGTGVQELIRNVERIRGRIDALTVPELKIEGLVTDTMGT
CRALREQKFEPILQTTCREKSRVDIQEHLLRASESGIENILAFTEDYRITGDSLQEIMFF
HVDSGKLFSVVESLKEGHDISGKEISFKPRFCVGSGVDSSWGKRVPDLEMREMEELAGLG
TQYFLTTPVFDLDSFNQFMAKVGPIRIPVIAEVILVRSAEMGLFLNKHVKPNLVPNHIIE
KLAKAPDKEKASIEIIRDLVKGLKDLCQGVHFIPIGAEDRISKYLDALKL
>B5JES2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiae bacterium DG1235|TrEMBL
MKSLREKLETTSDFLTGVELVSIRGTMATKSAIKARAFANDLIADTEVDWISITDNAGGN
PQLAPHSLGKPILYAGKEVVIHLTCKDLNRNGLESEAWALHSEGFQNILAMTGDYPVAGN
DGLAKPVFDIDSVGLIAMLHKMNRGFDHAELIKPHYEPKYEKTSFNIGAVTTNYKLLEGE
LIPQYRKLQKKVEAGARFIINQVGYDSRKVHELRLYMDQHGMTRVPLIGNVYLLNGKVAK
LFNTQRIPGVVVSDQLLQTCQKQAESPDKGRAYFHELAAKQVAIYRGLGYRGAYLGGAHN
HASIRKILDLANSFSPDDYKTFAQEISFSRPGEHFYYQQDPDTGLSDPHKKTPPSPRKSP
SIHYNISKWTHDHIFAPGTVLARQGAKACAKARDPLQGPAPLRALEHVSKNLLYTCKDCG
DCSLPDIAYLCPESQCAKNQRNGPCGGTREGRCEVDGYGDCIWLRAYDRLKASGKEENLL
SHSPMVQNQGLRNTSAWANNWLKRDHHK
>A0A7U8ICM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus 65-1322|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A6N2DIM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ilumatobacter sp|TrEMBL
MARISDLLAAGRTVSFEFFPPKTDSAQMSLGRTIAELAPLDPSFVSVTYGAGGSTRERTH
QVVTWVRQETSIAPMAHLTCQGHTRSEVDEILENYRAAGVQNILALGGDPPKDPADARPS
DYQYASELVDHVREAGDFSVGVAAHPELHPRSPDRATDRRTLAAKMAVADFAITQFFFEL
EPYVRLVNELADLGVTKPVVPGIMPITNVAQVSRMAEMSGAAVPASVLDRLASAGDDPEH
TRLIGVEIATELSAALLDAGAPGLHFYTLNRSTATREVYANLDLANSGAEPGRGANLGTG
TT
>A0A4Q6GRC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium|TrEMBL
METHNFSIEFFPPKTDEGAEKLRVVRQKLADLRPKYFSVTFGAGGTTQQGTLQTVLEIQS
EGFDAAPHLSCVGGTRESLRAILQQFQDKGIRRVVALRGDLPSGYGGGGEFRYANELVEF
IRKETGDWFHIEVAAYPEMHPQARSPQDDLQAFARKVQAGANAAITQYFYNADAYFDFVD
NARKLGVDVPVVAGIMPITNYTQLMRFSDMCGAEIPRWVRNKLASFGDDSASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQAAATTAIWQRLVK
>A0A1F4C5S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_64_23|TrEMBL
MESQKKYPPTFSFEFFPPKTQEGMEKLRATWRQLIQLKPRFFSVTYGAGGSTRDRTLEAV
LEIQKDGGNAAPHLSCVGSSRADLAATLELYRSHGLRHIVALRGDLPSGAAGAGELRYAN
ELVEFIRQTTGDHFHIEVAGYPEFHPQARSAQEDLQAFKRKVDAGANAAITQYFFNADAY
FRFIDDCEALGMDLPIVPGIMPIANFVQLARFSDTCGAEIPRWLRLRLQSYGDDVASIRS
FGLDVVTELCDRLLSQGAPGLHFYTMNQAGLVSTIWQRLGL
>F0I999|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis SK115|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVEAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A4R3XSN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas methanica|TrEMBL
MNISFEIVPRSLEAFDEQYGFVQTLDKGINIINVPDIQRFDTRSWELATRVDRSKYRFIP
HFRAIDFKIESGELYRIIEDYALDSVLLVSGDPPEGLKRSFYNTDVVDLIRAVRQRFPSL
HIYAGFDPHRSGVQDECDYIQRKVDAGAGGFFSQPFYDSRMIDIYAEHMLDLETYIGISP
ITSKASMNYWEVKNKVKFPKSFRPDYDWNVEFANGVIASAAANGLNVYFMPIRIDLARYF
GEIKLGG
>A0A318TEW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium leguminum|TrEMBL
MTIHELKSSQATRIAASIELAPKQAIESQDLPSLFPAGSRVYITDMGTDTVDTLTTAARR
VSDLGYKPVPHFACRRLTTKAALEVRIQRAAEEAGVTDVLIIGGGLERPAGEFNSTMQVL
ETGFFDRYGITEMGIAGHPEGSPDFSEAVAIEALRLKKNFGERTGARLRIVTQFGFDAEH
FIIWSEGLRDAGIDLPVHLGIAGPAKITTLIKYAAMCGIGNSITYLKKNALSLTALATSH
SPEGVVGPIERHVLENPTSNIKQIHVFPFGGIRQASEWLVERGTWNPHTVAPVAAAQ
>A0A4R9R227|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1D.F.Ca.ET.234.01.1.1|TrEMBL
MSARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPEAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRRPWKREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A8D9SM82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus 55/2053|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A8J7VE46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Didemnitutus sp|TrEMBL
MPPDSSIADLFSARRPLRSLEFFPPKDEAQLQAMHAAAHSLKRIAPDFVSVTYGAGGTTR
ERTARAAAMLRQEFGFTVMPHLTCVGHSAADLHAIADQLHAEGYRNIMALRGDPPKGETT
FVPYHDGLRYGSDLVQLLKQRHPDFCLGVGGYPEKHPEAVNAAVDLDNLKRKVDAGASFI
TTQLFFDNTIYYRFVERCRAHGITIPILPGIMPVLSLKQIKRFTEMCGAHLPPPLVARLE
AAAEIPDVVEIIGIDWALDQIRGLLANGAPGYHLYIMNRAKSALALAAGLAA
>A0A8B9M3K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Accipiter nisus|TrEMBL
MLLLFPSSRELTMVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPILDADRHERLR
EKMRRRQESGDKWFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKE
TSSMIIANTAVNYCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWE
EEVDGFNYAADLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRYLKEKVFAGADFII
TQLFFRSETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEP
IKDNDAAIRNFGVEQAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWTEDPRRP
LPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLF
YLKSKSPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNL
LKEQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALL
KVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDE
AFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNTQ
TQQ
>A0A6A6XS63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melanomma pulvis-pyrius CBS 109.77|TrEMBL
MMEKVTDKINALPEGANYFSLEFFPPKTSPGFANLQGRLERMSQALRPLFVTVTWGAGGS
TATKSLELAEICQRQLGLTTCLHLTCTNMSRSLVDEALEQAKVLGIRNILALRGDAPRSN
EYREEGQSPEEDSNKDFTWAIDLVKYIRKQYGDYFCIGVAAYPEGHSDESHPEHQDPLFD
LPYLVEKTKAGADFIMTQLFFDVGAFDRFEEMLRGHESGVFKTIPIIPGLMPIQSYNILR
RTTKLSHATLPTDILTRLDAVKGDDELVKQVGVQIVSEMVEHIKKRPSVGRRGFHFYALN
LEKAVSHIVEDCHLIPPTLTEDDDDAIDLNAPDITISPPNGIAARRRRLSSMNSSPHNRV
IISRPSKSSNASFEASESEAGIPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGDA
RSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKDDISRIFRKHIEGDLEAIPWSEQGLSPE
TSTIATQLLALNGKGWWTVASQPAVNGVPSTDPIFGWGPKNGFVFQKPFVELFVPSSDWK
ALQARLEEHEQITYFAGNARGDFEASSEDGVNPVTWGTFAGKEIITPTIIEEVSFKSWQE
EAYSIWREWQRIYPPRSATAKLLGEMREDVWLVNVIWGDFVEGKGLWDFLME
>A0A7G5FEG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium hindlerae|TrEMBL
MAITRQKPISSLLAESNKVMFSVEFMPPRDDAAEARLWKAAGAFKDLGASFVSVTYGAGG
STRDRTFRIAERLAALPLTTLVHLTLVEHSRAELLEILETYAQAGLTNLLALRGDPPGDP
LGEWIKATDGLEFTSELIELVQTTEASRHFDIGIAAFPEGHHRADTLDIDTEVTLTKLRD
GAEYAITQVFFDVEHFLRLRDRLVAADPEHGAKPIIPGIMPITSLRSVHRQIELSGATMA
PEVGARLEKAALSGDAAVRAEGIQISSEMTQRLIDEGVPDVHFMTMNFAKATHEVLHNVG
MAPAWEKS
>A0A1W6A0E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacillus mangrovi|TrEMBL
MKLNEALQHQTLIGDGAMGTLLYSYGIDHCFEELNLSHPEEVLNVHKAYVQAGADVIQTN
TYGANYVKLQRYGLEDQVKEINSAAVKLAKQAADPETYVVGTLGGIRGIQKQAVSLDEIK
RSFREQLYCLLFEKVDGLLLETYYDLDELLTVIEIARKETYLPIIAQVSMHEPGVLQDGT
SLTGALKQLEDKGASVVGVNCRLGPYHMIQALEEVPLPEKAVLSAYPNASLPGFQDGRLV
YSTEPGYFQKSAQALYEQGARLIGGCCGTTPEHIEAIAAKVKGKKPIEKKDVPVKQPEAI
EVAERENRPPHLHELASEGRSIIVELDPPKRLNTDKFFEGAKALQEAGVDSVTLADNSLA
SPRISNSAMASIIQSKYGINPLVHIACRDRNLVGLQSHLMGLHTLGITEVLAVTGDPTKI
GDFPGATSVYDLSSFDLIHYIKQLNKGISFSGKSLGQSTSFSVAAAFNPNVRNLNRAVKR
LERKLSYGADYFISQPVFNQQQIIETYEATKHISAPIYIGIMPLTSLRNAEFLHNEVPGM
SLSPDILERMENVNNDREKAQAEGIAIAKSLIDTALDLFNGIYLITPFLRYEMTVELTHY
IQEKTKERQERKVTDGIHII
>A0A1C0A781|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orenia metallireducens|TrEMBL
MSLKDKILNKETGIILYGLTPPKEKNTTDRIVEISQKQISRIKNLDIDGLVLYDIQDESD
RIKEERPFPFLPTIDPAIYSRNYLDELKIPKIVYRCVGKYNEDEFSKWLTSDIKTDRFSV
FVGAASKDQDVNLKLREAYELRQKLNPNLLLGGVTIPERHSQSENEHLRVLSKIKSGCKF
FVSQAVYNLEYSKNFLSDYYHYCQENNLEMVPIIFTFTPCGSKKTLNFMKWLGINIAKWL
ENDLLNSEDILEQSLNSSKKIFEELLDYALEKGIPIGCNIESLSIRKAEIEASIELAEFV
KETFKKKVNKI
>A0A1J4P3L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces mangrovisoli|TrEMBL
MTSLSTASAAVGTSLLEDFSLEMTGKDVPKLEEARHTIPPGTRINVTFLGNENLRMRLEA
ARAVKRLGFVPVPHISARRLGSRAEFEEFLDGLRADGTCDNVFTVGGDPARPEGPYEDSL
ALIESGLLQEYGVRDVGVSGYPEGHPGIAEDVLWTALREKDAALAVQDLDGGVITQFGFD
ADPVLAWVERVRDQGIALPVRVGVPGPAGVRRLLSYAARFGVGTSASIARKYGLSITNLV
GTAGPDRFLHALAEGYDPARHGDMKIHFYTFGGLRATAEWVDRFRKDSTA
>A0A2A2MCI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hafnia paralvei|TrEMBL
MSFFHANQREALNQSLAELHGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGGGKPDMYACDLVSLLKEVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMTNMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEIHAPI
TA
>R6CKT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:579|TrEMBL
MEMKKLFENGRTVFSMEIFPPKKPGTIESIYSTLDGLADIKPDFISCTYGAGGNPADTST
IDICRIIKEKYGILPIAHFTCVNNTRADIDKAIELFRAAGIENVLALRGDKNDKYPPKED
FHYAADLIKYLKEKAPELHISAACYPETHPEAKSPVADILRMKEKEQCGAEHFMSQLFFD
NEDFYAFREKTQIAGIKSPIEAGIMPVTSKAGILRMVSMCGASVPKKLARILNKYENNPE
AFADACVHYAIDQIADLITNDVDGIHLYSMNKPDTAKKIFEAVKNML
>A0A285GNH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orenia metallireducens|TrEMBL
MSLKDKILNKESGIILYGLTPPKEKNSSDKIAEISQKQISRIKDLKIDGLVLYDIQDESD
RVKEERPFPFLPTVDPAIYSSNYLDELKIPKIVYRCVGKYSKDQFSKWLTSDIETDRFSV
FVGAASKKQDVNLKLREAYELREKLNPKLLLGGVTIPERHCISEDEHLRVLSKVESGCKF
FVSQAVYNLDYSKNFLSDYYHYCQENNLEMVPIIFTFTPCGSKKTLEFMKWLGINIAKWL
ENDLLNSEDILEQSLNSSKKNFKELLDYALEKGIPIGCNIESLSIRKAEIEASIELAEFV
KNTFEKKAK
>A0A3M6QYT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corticibacter populi|TrEMBL
MASPLLHLDTSRPANITDDYSLEVNAKGISALTAAAHRISPASTISIPYLPNQDNEARLA
TARAVRKIGFEPMPHISARRVTSLAELQWFVEHAVAEAGVERCLVIAGDPATPMGPFANS
SLLIETGVFERSGIKVIGVGGHPEGHPIMSAADRWEVLKRKCQDIERRGMTPLIFTQFAF
DAGIVLTWLEALRERGIEHRVRVGVPGPAGVAVLARYAAMCGVGACASMLSKYGISIGRL
FGTAGPEHFVDRLAADLTEVHGKVSLHFFPFGGIAQSVGWVEQYRSRSELAC
>L9MT49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WC-743|TrEMBL
MSKRIPISFEFFPTKTDAGAEKLKIVHQELQQFNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGDHFKIEVAAYPEMHPQAESYDADIQHFIEKVNAGANAAITQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVIKLCERLIAGGAPSLHFYTMNHTEPNRQLILDLGLA
>A0A3M6QKR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corticibacter populi|TrEMBL
MNHTQHNKHGSPLPVSLEFFPPKTEAGAAKLKGVRQALYALQPEFCSVTYGAGGSTQAGT
FATVAEIQAEGIPAASHFSCIGATREKVRAELQQLRGMGVKRLVALRGDLPSGYGMGGDF
HYASDLVAFIRAETGDAFHIEVAAYPEMHPQAHSPEQDLQAFATKVRAGANSAITQYFFN
ADAYFRFVDEVRAMGIEAPIVPGIMPILGASQLLRFSDACGAEVPRWLRLRLRGYGDDVE
SIRAFGLDVVTALCERLIAQGVPSLHFYTMNQSEPVREIARRLGLGPHG
>A0A0A6VWC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria polaris|TrEMBL
MDPPHAGPAAALLRDFSLEMTGKDVPALEEAAAVVPAGTRINVTFLGNEDLGMRVAAARA
VREHGFVPVPHLSARRLRSQGELEEFLAALAEVGAAEHVFVVGGDPETPEGPYPDSLSVI
RTGVLPRHGVRGVGVSGYPEGHPGIDDAALWSALTDKTAAIREQGLEPEIITQFGFDKDP
VLEWLAEVRRRGVDTPVRIGVPGPAGVRRLLGYARRFGVGTSAGIVQKYGFSLTNLLGTA
GPDRFLRDLAAGLDPAVHGQVLLHFYTFGGLRATAEWVREFGTDGGTP
>A0A2E0R8E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiritimatiellaceae bacterium|TrEMBL
MSLLETLQHKPLIGDGAMGTMLYAKGIFINTCYEQLCLTKPYLIECVHRDYVEAGADLIE
TNTFGANRLKLEAHGIADQLEAINRTAVHLARKSAGPNTYILGSVGPLLQSDQLFSDRHT
SELEHLFHEQIALLADEKVDAIQLETFTHVDEAELAAQITASYNLPVFVSVTVGKDGETR
RGERIEQIIHQLDACDAVDAIGINCGLGPAAAFSIAERALPLTSKPFSVNANAGLPQEVD
GRLIYMSTPEYFSEYAKRLIELGVRMVGGCCGTTPEHIATMAKQVKSLSGVKEHLHIKHH
TDQEATPIETIPTAAKCRFGAKLANGEKVTSIEITPPRSIDLKPMLEKCQQCYDAGIDAI
NIPDGPRASARISPMVAALAVEREIGIETVLHYCCRDRNLIGMQSDLLGGYAGGLRNYLI
VTGDPPKLGDYPDSTAVFDVDAVGLTQVVNNLNHGIDVGGNQINPPTGLLIGVGANPCAV
DPEREINHYLNKINAGAEYAITQPIFDAEALLRFLDSVEKKGDSIPVVAGVWPLISYRNA
QFLKNEVPGVEVPDALLERMSHAKTKEDGRALGIEIAREIRDVITDRVAGFQVSAPFGIV
DLALQVLE
>A0A8C0RYX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Canis lupus familiaris|TrEMBL
MDQPPPGVLPATVRCSRLGLWTLEAGRVGFSVPPSISRSPAMVKEPRGDGDGGPTPRSEG
SSSGSESSKDSSRCSTPGLDPERHERLREKMRRRMESGDRWFSLEFFPPRTAEGAVNLIS
RFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQI
TGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYP
KGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFP
IQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGL
HFYTLNREMATTEVLKRLAREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFG
ELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYLSGEPNQHGYKVTCLPWNDE
PLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTS
RETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGFMFWKDEAFALW
IEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLKGPSPERE
AEAV
>A0A6M8WWN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium indicum|TrEMBL
MALKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTRAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKAENGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRRQTKSAGAAA
>A0A8F6NJZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELCTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A848W8R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MNLLSCPASETSAMAEPTLPSASPPIDSALVRTLLAGEFAVTAEVVPPLSGDAAALIAKA
QPLLGLVDGLNVTDGAGARSHLSSLVAAGLLVREGHEPVLQFTTRDRNRIALQSDILGTS
ALGIQNILVLGGDDPKAGDQPDAKPVFDLDTGELISMVREMGDPGKLPSGREIESPPKLF
IGAADTPMDPPADWAPDRLASKADAGAQFVQTQFCYDIDIVRRYMARLGDAGLTDRLFIL
LGTGPIGSARSARWMVKNLWGVIIPDAIIERIEGARDEKAEGHKICIEYIEQVREIAGVA
GVHVMAINQDEAIPDILAAAQAGPTFRTART
>A0A7Y7CNN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MAQRHYPHGSHSLFEEAVDDVNVSFEFFPPKTPKMEETLWQSIKTLEELNPKFVSVTYGA
GGGTRERTHKTVKRIVDETNLKPAAHLTCVGATRDEIDEVVRDYHDAGVRSIVALRGDPP
EGASRYEAHPGGYANAAELVEGIRKIADFDISVGAYPEKHPDSPTLAADLDNLKRKVDAG
ANRAITQFFFEPDQYFRFLDHCQSYGIDVPIVPGILPVTNYKTLKSFAATAGASVPKWLG
DLFDGLDDRPQTRSLVAATVAGEMVRRLYAGGVRDFHFYTLNRAELTYAICHMLGIRAGA
EETQ
>A0A660LKB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp|TrEMBL
MVPFSSQLGSPSPSADSQPPRSADSPPARRTQTVSFEVMPPRRPERVVGFWRTIDELRPA
RPDFISVTYGAAGKDRFSARDIVTRLCRDTPVSPIAHLTCVNTSVSTVEAVIEDYLDADV
RTFLALRGDPPIDDPDWSPPPGGVSSATELVALIRSVETRRCARHASAALRAAVNPLTIA
VAAFPSGNPAAGTSPAQEVERLLLKQAAGANFAITQLFWDPEVYISFVDDAKRAGVTIPI
LAGLLVPTDIGRLSRTAELTGIDPPQALSQTLRDAEGAEAAVQAGILATARVARAVLDSG
APGLHLYTYNKARPSLGLLARIGLFDPAA
>A0A1B8FQK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. 03VT05|TrEMBL
MADSPTTDKITDKIAALPQDASYFSLEFFPPKTAMGSTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSKALVDDALKAAKEAGIQNILALRGD
EPRGEYKDALEEGKEGEDEFVWAIDLVKYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
EHDLPYLVDKVQAGADFIMTQLFYDVDAYDNFEKVLRDHSSGAFKTIPIIPGLMPIQSYQ
ILRRTTKLSNAKLPESIIDRLDAVRTDDEMVKKVGVDILAEIVESVKATKQRTKGPKGFH
FYTLNLEKAVAFILERVNLIPSFTPVLTSDVFAVDDITDTIPLPQLLINGEKKNRRQSSV
GSGPHNFVIIDREKASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRPDITSIFVQYLNGTLSALPWSDE
PIAAEANLIKDELVKLNQKGWWTIASQPAVNGARSQDEVVGWGPKGGWVFQKAFVELFVP
TFDWARLKPLLEGNAKVSFLAQSASGEFLKSKLDLGPGEEGTETNAVTWGVFPGKEIVSP
TIVEEVSFRAWAEEAWQMWGEWAAVFGKSGEESRRFLDGVAKDGWLVNIIWHDFVGMCKA
KEGRFEEEGYKGLWDVLIEA
>A0A1R4L0X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. JB170|TrEMBL
MKIVDHIKDANGKTLFSFELLPPAKGQGIQSIFQTMDALMEFKPPFIDVTYHREDYMYKQ
HDSGLLERIAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDSDFIPSTGGHAYATDLLRQVHEMNQGKYLHEENVISEKTDFCIGVAGY
PEKHFESPNFNTDFKWLKKKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLISLPKIFHLDIPESLSEAVDECKTNADVRKVGEDWLVEQCKELIKFGAPVLH
FYTMSNPGPTKKIVERLA
>A0A2E5KUE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTVEAAVSPIVERLSALALRFSGMEHLGVSFEFFPPNTAEMEETLWTSILRLAPIEPDFI
SVTYGAGGSARDRTHATVRRILDETSLTPAAHLTCVAATREEVDEVARAYWEAGVRHIVA
LRGDPPEAGADYAPHPGGYTYAVDLVEGLARVADFDISVAAYPETHPEAPDEAFDLENLK
RKVDAGARRAITQFFFDTEVFLRFRDRVRRAGIDVPLIPGILPVTNFEQVVRFAGLCGAG
IPGWLSRLFESLGGDPETRKLVAAMVAGEQCRILAAEGVSNFHFYTLNRADLTFAMCHTL
GLRPSTNDAEANQVL
>A0A537V4A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSDKSLAAAAPQRGLLSADPVGDFDGAAPRVSFEFFPPKTPEMEARLWEVIKRLESLAPR
FVSVTYGAGGSTRERTHATVRRIRNETALEPAAHLTCVAASCEEIDRVARDYWEAGIRHI
VALRGDPPGGLGSDYAPHPGGYAYAADLVAGLKRVADFEISVAAYPETHPTARSSGHDLD
NLKAKLYAGASRAITQFFFDVDLYLRFRDRAHAAGIRVPIVPGILPVTNFAQLTRMAAGC
GASIPGWMAAHFDGLDDDPDTRRLVAASLAAEQCRRLHANGVH
>A0A5S5C977|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimarina intermedia|TrEMBL
MKVTDHIEQSKGKTLFSFELIPPQKGRNIQELYNNIDPLMEFNPPFIDVTTSREEYIYIN
KKGLLDKKLTRMRPGTVGICAAITHKYNVDAIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFTPTNGGHCYANELVSQIVAMNQGKFLHEVVETETNSDFCIGVAGYP
EKHVEAPSLNSDLRRLKEKVDAGADYVVTQMFFDNQRYFKFVEEARAAGISVPIIPGIKP
VSIKKHLHLLPQVFKLDMPDELVKAIEKCKTNAEVREVGVEFAIHQSKELMAYGVPVLHY
YSMGKSDNIKKIAAAIF
>A0A537PD76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTSKPELRISFEFFPPKPGEASDNFWKVIKKLEEMKPLFVSVTYGAGGTTQERTLGTVNS
ILERTSLAPAAHLTCVGATRAEVDSVVRGYWQAGIRHIVALRGDPPGGVGGRFVPHPQGY
RNAADLVRGIREIAPFEVSVSAYPEKHPDAVSIEEDLAFLADKAEHGATRALSQFFFNNA
AFLRFRDRVFARGIEIELVPGILPITNFARVKEFASKCGAFLPPGLAQRFHGLDADPETR
NLVAAMVAAEQIDFLRREGVDSFHFYTLNRADLVYAICRVVGLGEEAEAA
>A0A539CZR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSAGDRDVPDDTRELKPGHSSAGHLEALLRSGEFAVTAELSPPDSSDPEEVFRRARVFDG
CVDAINATDGSGANCHMSSVAVCALLTRNGYSTVMQVSCRDRNRIAIQGDVLGAAAMGVA
NVLCLTGDGVQAGDHPQAMPVFDLESISLLQLLRGMRDEARFQSGRKLTQPPRVLLGAAE
NPFAPPLEYRPQRLAKKIAAGAQFIQTQYCYDIERLKTFMTVARDLGLPGRAFILVGVGP
LASARAAEWIRTHVPGVYIPDAIIARLAGSHDQKREGRQICIEIIQ
>A0A4Q0Z7N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp. F2176|TrEMBL
MLTDKIRNKNSGILLYGITPPKIKHTEEEIQAIAQKHIERISNLPIDGLVLYDIQDESDR
TDEKRPFPFIKTLDPCEYSRTYLKDLVIPRVVYRAVGNYDEKTFPVWLELTKENQVHSVF
VGAASREQKKPMTLKEAYRLKKEVNNNLCMGGIAIPERHMVKHDEHLRVFSKIDNSCEYF
ITQCVYNLEASKIFLTDYAKYAKDNEKEVVPIIFTLTPCGSAKTLDFMKWLGISIPNYLE
EDLKASGNILHDSMKLCVDIFRELYTFGRDRGIPIGCNVESVAIRKEEIEASIELLHEVK
KIMEEN
>A0A1P8KQ46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poseidonibacter parvus|TrEMBL
MFETLIQKLQEDKYLTLETTPQHEPSMHNIIERIKKFNLQSKVDGFSCTDNPLAKLKYNA
LFASLKLQQEFSKPVIATMSMRDRNKIALQSDLLGASDFDVRAILALTGDPAKMSDQPHA
KGVFEANSLMLLKIIKSFNYGMDFAGHPFKIEPKQIFPFSVVNSYAKSFTSLEKKMHNKI
QNGSLGIITQPLFDVDNAKKLLESFDKAKEDVEGDKKKSQLIIGLFPITKLRTALFLSAQ
VPGIHVPQMWINKLESAHKISVDEEYKVGMQLSQDIYKEVRKIHPKVHLMTANKFDIANE
IIS
>A0A7X0NLA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea rubra|TrEMBL
MPFELICEIEPPTKPDLKHVRHQIGTLSKIAHAFLIPDNHIGRATVSSVAVAHEVEAMGG
RGIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTSGNRTSDLNVRSMIEEARGF
SPDLRVGAAAGLRALPAWKRTADFLFSQVSFSVEEQLRWREEHPVDVPVYAGVMVLASER
HARTLAAAIPDIALPEELVARVAADRMAGVEAACEQVLALRDSGAFAGVHLVPVARYRDV
ESRLAAAL
>A0A2V5LFF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter livingstonensis|TrEMBL
MLPTRLEIIPTRDIVPSVLASVSVGTTITVTCLPHHGVERTLETAAALAGHGFNVVPHLA
ARSVASREQLARILLACSTSGITEVFAIGGDSAMPAGPFASSESLMREIADLAGNDMRIG
VAGYPEGHPSISDSQLMDSLLAKQELASYVVTQMCFSAETISRYMAGLRSEGVLLPIWAG
VAGAVPRTKLVLLATKIGVGSSLRFISGKGALGRNLLGGGRYRPEQLTAELEASPAPPSG
IHLYSFNNVGPHQP
>A0A7C0YIJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MALSKFMESIKSSEFTISGEVDPPKGANRDTIVHQAELLKPHVVAANVTDNPLGIVIMNT
LVPCHIMQNEVGLEAVYQVTCRDRNRIAIQSDILGAAALGIKNVLALTGDHPSLGDHPQA
KPVFDLGSVELVDLLRTMVHDSTDYAGNKLDVAPEMAIGVALSPGVDPVEPEIMKLEKKI
AAGADFAQTQCVYDTGVLEKMLDATSHLDLPILPGIAPLKSVGMAKFMAANVPGVTIPKE
MIDTLKNAKDIKDATIEITAGLLHDIKELGFAGVHIMPVGMDAYVGEIIERAGIR
>A0A840MHI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinivorax tropicus|TrEMBL
MNQTFSFEFFPPKTTEGVEKLRNTRRQLAQFNPNFFSVTFGAGGTTQQGTIDTVLEIQSE
GQQAAPHLSCIGSTRDNIRSLLNLYREQGIKRIVALRGDIPSGMVEVGEFRYANELVEFI
RLEHGDWFHIEVAAYPEYHPQARTALDDLDNFARKCKAGANSAITQYFFNPDAYFAFVDE
VKFRGVDIPIVPGIMPINNFSQLARFSDTCGAEIPRWLRNKLQAYGDDVASIRSLGLDVM
TDLCDRLLTAGAPGLHFYTLNGAGAVSTIWQRLGL
>A0A7K5JUA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mionectes macconnelli|TrEMBL
MVNETQQSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELRDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGHKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVMALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A519BYE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MKFRDKVRKPKRPVVVYEILPPREKDGTLNSYAERISSLLSQTHIDAINIPEVHDENGRG
IRPIKNLERAEAREFGRLLQDNVGIEAIVNRVTVHDKLEDQKNWIKETFYDYDIENLILV
GGESSTVNYPGPSVNKTSEYITRDLNTGRFDFFCGGIAIPSRKIESERLLRKGSNGIEFF
TTQVLYDAKKIKKMLKYYDDICKKNEVLPRRILLSFAPVSSKKNIEFLKWLGVEIPNTTE
ERLENEKTTMTAESLDIASEILKDVLTNNEKLGIDLQGILY
>A0A7R7C3T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L-8-3|TrEMBL
MNQFRFSRRPDIGGKIRVSFEFFPPKSDEMEARLWDTVTRLAPLNPHFVSVTYGAGGSTR
ERTIRTVRRILNETGLLPAAHLTCVDADQDAVDGVIGEFAAMGVKRFVALRGDPSEGVGA
AYRPYPGGYANGAELVAALKRVDDFDISVSAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFGQVANFSSRCGAHVPDWLAERFD
GLDKDPQTHALVAAAVAAEQVLDLVERGVTDFHFYTMNRADLAFAICHMIGIRGDLAVKR
AAPAAA
>A0A3R9KKZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus cristatus|TrEMBL
MVNRQTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLAE
FISNDLEIPTIAHLPAVYLTQEMVSNILQALDRVGVNQILALRGDIFPDVAPKDDFKYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRT
AGLAYAVDQIVDLVTHDVAGIHLYTMNNAATAYHIYKATHALFNHTPSVQSF
>A0A1S1J999|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium tructae|TrEMBL
MKVTEHIENAKGNTLFSFELIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNSYAIDLVRQINDLNSGKYLHELMDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFAFVEKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIARQIF
>A0A1V9H0R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas phaseoli pv. syngonii LMG 9055|TrEMBL
MISTDTPHLASTVADAYSLEVSVKDIGALTNAAPRILPGCAMFIPYLPGQNEAARLAAAQ
TVRGLGFEPVPHLSARRIGALEELQASVARLVDEAGVTRCLVIAGDPATAKGPFPDSVSL
IETGVFERAGIRSVGVAGHPEGHPIMGTTEQWDVLERKCHSIQERGMAPLIVTQFGFDAD
LVVTWLEALRARGMSHPVRVGVPGPASVAALARYAARCGVGACASVLSNHGISIGKLFGN
AGPDRFVDRLVSRLTQAHGDVRLHLFPFGGIAQSVEWVAQYRSRNASQRLVSSEPADQT
>A0A380RWR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter succinogenes|TrEMBL
MKIIDILKQDKMSLSFEVFPPKKETSFENVKAATEAIAKLNPAFMSVTYGAGGGVSQYTL
EIAKNLKYNFNIPMLAHLTCISSTKETIHQRIEDMKAAGIKNVMALRGDLTPELIANGRG
DCDYHHAVELIRELKAADADFCIGAACYPEKHPESPNQAEDIKHLKEKVEAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPDAMKQAGIIYATDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFAG
>A0A6N9TTH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dissulfurirhabdus thermomarina|TrEMBL
MGRLHETFRRAFEDREHRRSGGIRTARPPSRAFAATFELVPGRASRSQAYDASVAFARDA
ARDGRLAALSITENAGGHPALSPPVLGREIRDLGMEPIIHFSCKDKNRNEIESHLFELDR
YHLRNLLVVTGDYPRFGYEGQAKPVFDLDSVLALGLIEAMNRGIVLDPRAPGGGQRLPRL
DFYAGAVVSPFKRLEAELVPQYAKLRRKVAAGARFIITQMGFDVRKYDEVLRFMAHEGLR
VPVLATVFLPDLRLARLLNRGVVPGCVVPDAVLAAVERETGAPDGGHGARIERGARLVAI
LKGLGFDGVHLSGTGLTYDDVSRVLDRAAEIGDEWPDLVPEFLHPGAWDFWYFQEDPATG
LNSDRPTPLRRRRLHPAAAAGFRINRLVHRLFFRAEGPLFGMLREIARRIEGSPLEGAFT
RLEHWVKEGLFDCQRCGDCTLDALAFLCPQSGCAKFLLNGPCGGSRDGWCEVWPGRRRCI
YVRVYQRLRSVGGVQALSAMPPLPPRDWSLYRKASWLTFFLGRDHHRAGRDADGEGGG
>A0A832KCY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desantisbacteria bacterium|TrEMBL
MSALRDALKQGRFVITGEVGPPKGTDITKLMEEAEIIKNRMVAINVTDIQSAVMRLGSMA
VCHLLKEKGIEPIFQMVCRDRNRLALQSDLLSAYVLGIENVLCLTGDYPTLGDHPGTKPV
FDLDSVQLLAAAKGLCEGHDMAGNALEGNPDFFLGAVVTPGADPVEPQILKMEKKVKAGA
QFFQTQAVYEIDKFARFMEKVKYLNVPVLAGIVVLKGAKMAEFMNKNVAGVHVPDNIIDE
LKTSTDRVKTTIEISARLIRELKQLCQGVHIMPLGWGHHIPAILDAAGL
>A0A432UIX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfatator sp|TrEMBL
MSRFAEILRKKDFVITFELVPGRSTRTRHFRAIMRFAEEVAEAGLFDALSITDNAGGHPA
LAPEALGRELKRLGHEPIIHFSCKDKNRNVIESDLLDLDREGLRTLLVVTGDYPRYGYRG
RAKPVFDLDSVQLLRLISEMRKGYVLPPEVPGGGVTLPPVPFFPGCVVNPFKWTEAETLL
QYWKLLKKIRAGASFVITQVGFSARKYQELLFFLQEEGLSGFPALAGILVMDQRLARILY
RGIVPGITVPEGLYRRLMGLSEEEARKEALERAARLMAVCQGLGYRGVHLCGAPLEKEAV
HQLLVLYEEYRPHWREFLPEFAEVPEKAYFLYRKDPRTGLNLPERKPLSPSRSRNLLYFF
SRIAHKLFFTRKGPLARPLRFLAHRLSGSSWEPLFTRLEYGIKKVLYDCQECGDCSLPHL
AFLCTQSQCAKYLLNGPCGGSRDRWCEVYPGRRRCVFVRIYERLSPEERPQVFLKELSPR
NWNLFRTSSWLNFYLGRTTLSPKKVKDL
>A0A4U1DBF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robertmurraya kyonggiensis|TrEMBL
MSFLDRLKNEILIADGAMGTLLYSYGTDSCFEELNVSHPNDILKIHEAYIAAGSDIIQTN
TYAANYLKLQRYGLEESVKEINSAAVKIAKQAAENKAYILGTMGGNRGVNPKAISIDEIK
RSFREQLYCLLLEGVDGILLETFYDLDEIETVLAIARKETNLPIIAQVSIHEPGIMQNQM
PINEAFERLEALGADIVGLNCRLGPHHMIKSLEEAQIPKKAFLSAFPNASLPTYTDGKFH
YEGDADYFKKSAQAFREQGVRLLGGCCGTTPDLIHSFAEELKGTKPVTEKTVRIQRVSSI
PIEHSPIERNNTPLQTIASVRPSVIVELDPPRKLNTTRFFEGARALKEAGIDAITLADNS
LASPRIENSALAYLTKTQVGLRPLVHITCRDRNMIGLQSHLMGLHTLGLNDVLAITGDPA
RVGDFPGASSVYDVSSFELIQMIKQFNEGLSISGKDLGQKGDFSIAAAFNPNVRSVEKAV
QRLEKKIKYGADYFITQPVYSEEKLIEVHEATKHLDTPIYIGLMPLTSSKNAEFLHNEVP
GIKISDSIRNTMAALQDDPIQSAREGIAITKSLIDAASELFNGIYLITPFLRYELTVELA
QYANENSSVLGRKQNV
>A0A7C3SJZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans|TrEMBL
MSKLREALDAGRFAVVAELIPPKGVNVADMLAPVAALKDKIESFGLPDNKQAEMRLSALA
ASRLVQEAGGEPLLHLSCRDRNRLALQSDLLGAAALGIENLLLVSGDYVTLGDHPDAKPV
YDADSAQLLQVARRMMDGRDSAGQALHGNPTFYLGAVVVPEAEPPGPQFLKFKKKVTAGA
QFFVTPPVFDLEKLRIFQRDMPAYPIKLLAGVKVLTPAEAAQAESGQWRQVYRVPPEIWE
RLQGKGEEDFFRAAVDLAGRLLRQIKEENLADGVYLMALGRTDWLTDILKIAGI
>A0A812WCT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiodinium necroappetens|TrEMBL
LLERAEKANTSDEAFKEFGIREGVAMCQKLLDGGAPGLHFYTLNLEKVVVGILKGLGKIS
DAQAAAFQSVEADAKFMVSAQGITTGTQVSNRPTLPGNKPLKEADPVMFDLVQQEKARQT
RCIELIASENFTSRAVMECLGSALTNKYSEGQPGNRYYGGNEVIDKVENLCKDRALKAFG
LDEKAWGVNVQPYSGSPANFAVYTALLPPHARVMGLDLPSGGHLTHGYYTAKKKISATSI
YFESLPYRVHPETGLIDFDELRKTALVFRPAMILCGASAYPRIIDFGKFREIADEVGAIL
MADIAHISGLVATGEHPSPFEHCDIVTTTTHKSLRGPRAGMIFFKYTDKIPDIKERIDMA
VFPALQGGPHNHQIGALAAQLLEVDSPMFKEYAKQVKANAKALADTLMSKGHKLASDGTD
NHLLLWDLRPHGLTGSKVEKICEAASITLNRNAVHGDASALAPGGVRVGAPAMTTRGCTE
QDFKTIGDFLDRCCQLALKIQAEKGKKLKDFEAAIPSNQEVAALKKEVEAWASKFGYPGL
>A0A6A6A169|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dothidotthia symphoricarpi CBS 119687|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTSMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRALVDEALEQAKVLGIRNILALRGDAPRSEE
YRDEGQLPEQDSNKDFTWAIDLVKYIRSQYGDYFCVGVAAYPEGHSDESHPEHQHPSYDL
PSLVEKTKAGADFIMTQLFFDVEAYDRFETMLREHESGAFKTIPIIPGLMPIQSYKILRR
TTTLSHANLPADILARLDAVKYDDERVKQVGVKILNELVEHIKARPDVGKRGFHFYTLNL
EKAVSHIVEDCKLIPRISQNEDEDENAIETTPAINLEPPNGALLTRERRRLSSINSSPHN
RVIISRPSATKSSNHSHEVLESEAGIPKGPINTRANTLAISEGEGSLGREATWDDFPNGR
WGDARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKGDISTLFKRHIEGDLDAVPWSEQH
LSEETLTIAPQLLALNAKGWWTVASQPAVNGVKSTHPVFGWGPKNGFVFQKPFVEFFIPS
SAFNELKPRLDAHDQITYFAGNAKGDFEASQEDSVNPVTWGTFAGKEIVTPTIIEAVSFR
SWLEEAYSIWREWQRVYPPKSQSGRLLKEVREDVWLVSIIWGDFVEGGGLWEFLGA
>A0A8F8UBM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea coxensis DSM 45129|TrEMBL
MLASGKRTFSFEFFPPKTDEGERQLWKAIRELESLRPTFVSVTYGAGGSTRDRTVDIVER
IAHDTTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVRGDPPGDPTGEWVRHPEGV
LYAEELVRLVRQAGEFCVGVAAFPYKHPRSPSIEADTEHFVRKCRAGADYAITQMFFQAD
DYLRLRDRVAAEGCDTPIIPCIMPVTQLSTIARSEQLSGAPFPTDVAARFEAVKDDPAAV
RRLGIEHGAELCQRLLDEGAPGIHFITFNRSSASREVFQRLEPASSPA
>A0A7U4JNI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sporogenes|TrEMBL
MHIKELFNQKNLVFSFEIFPPKVTSSIETIYETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTREDIDSIINELKENNIENILALRGDILKGKNIIGE
YNYAFELIRKIKENNNFGIAGACYPEGHIECESLEKDIKELKRKVDAGAEHLISQLFFDN
NTFYEFLNRTEQKNIKVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKEA
IRDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKGVAV
>A0A6J1QIV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Temnothorax curvispinosus|TrEMBL
MKYFVASKSFPRGNPARFTEDMEEYSPLFYSLTWHNEAASSNDSYLPLDLVENFPPNTLL
HLAAKGLKRDEVVRILKKTLALGIVNIFALRGDSLSENGDFEHAADLVAFIREQFGDTFC
VCVAGYPQTHPESSSKELDLHHLKAKVEAGADFIITQICFESRLLIDFVRDCREIGIRVP
ILPEILAPASHACLEKMTDICGLDVPVEIKDDLARMKDDDRAARKYSVDLITRIITDVIR
SGVTRGFHLSTLNRLSLVAEICKRVKFLGAENS
>A0A8D6L240|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. C5S11|TrEMBL
MIKEYLKNHVLISDGAMGTYYSELTGNDASYCEFGNLNDKETIKKIHDEYINAGAKLIRT
NTFSANTYDLGVSKDRLSDIINSGINIAKEATKNKSVFIGASIGPIKEDNIDESHDEILN
EYKFIVDCFLVNGIDSFVFETFSNYNYLKEISEYIKSKNSDSFILTQFAVKPDGFTRDGL
SVTKLVKEVKKIENIDAYGFNCGSGPSHMSEIIKKINIGNDIVSALPNAGFPEIIHERTI
YPKNSKYFAKKVDEIKAMGVSIVGGCCGTNPKYIKQLASLIIENSKVVKTISTYEETAKE
HEKKMKNTFKEKLDNNKFVVAIELSAPIDTDISKLITGAKICKENNIDLVTVPDSPMSKV
RADSTIIASKIKREIGIEVMPHICCRDKNTNAIRSSLIGSHIEDIRNVLAITGDPISDAS
KVETKSVFNLNSFRLMELIDDMNVEFFKDDNILIGGALNLNVLNKEVEFNRMLKKIEKGA
KFFITQPIYDDEAIEFLKKIKERTNVKILAGLLPVVTYRNAVFLNNELAGVTIPDKYVKM
FSEDMSKEEAQEVGIKISVEIGRKLKGICDGLYFTTPFNRVSMLIEIIKQIKD
>A0A5Q0GU41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix syringae|TrEMBL
MTSVVERLSGDKPVFSVEFFPPRDPADEAVLWRAIRELEPLDPAFVSITYGAGGSTRDRT
IRTTGRVVQETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILAVRGDPPGDVNGEWV
RHPEGLNYAEELVRLCRELGDFCVGVAAFPYGHPRSADLDEDTRYLVRKLRAGADFAIAQ
LFLDADDFLRLRDRVAAVGCDTVLLPGLMPLTTRRTLAKTVELSGAPVPAAVARRLEPFL
DDPVAFRAEGVDLVTEMGQRLLAEGVPALHFYTFNRSKATREVVGRLGLVPARA
>A0A401GWU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sparassis crispa|TrEMBL
MKISQKIDQANKEGRVWWSFEYFPPRTAQGLQNLLDRIERMRRLGPEFIDITWNAGGRTS
DLTSEMVKTCQSLIGIETCMHLTCTNMPKEKVDVALREAKQHGCRNVLALRGDPPMGKDE
WEAVEGGFVHGVDLVRHIRNQYGDYFDIAVAGFPEFHTLPPDERDLEMQYLKAKIDAGAN
FIFTQMFYDVEIFLDWVKAVRAAGITVPIVPGIAPVQTWNGFLKATSLAKISIPKSFMVA
LEPYQNNDEKVRAIGTKLVAEICRRILREDIGIKGLHFYTMNLEKATRMLLEELSLVPRV
EVLKPLPWRQSLTPSRRAENIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQTKEEALKLWDHPTTPAQLGALFSQFCLGKLAALPWSDQMPSSETSVIATQLA
KLNEYGFLTINSQPAVDGARSDDRVHGWGPSNGYVYQKAYLEFFVSPELLELLLPHIERD
TNITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGCQ
WANYYEPDSPSRKLITNVMDTYLLVNVVHNDYRKPSAIFEPFFKAGEEFATRHPPQPVLN
GHAH
>A0A1H4JI92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter dokdonensis|TrEMBL
MKVTDHITNAKGKTLFSFEIVPPVKGKNIQELYNNIDPLMEFNPPFIDVTTSREETIYIK
KEGLLDKKTTRMRPGTVGICASIQHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIQNV
MALRGDARSEQKYFEPTEGGHPFAIDLVKQIQDLNKGKYLHETVESEHSSEFCIGVAGYP
EKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEAAKEIGITVPIIPGIKP
IAVKRHMQLLPQVFRIDMPQDLIEAVDACATNKDVRKVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAEALF
>F4CVR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 / CB1190)|TrEMBL
MTTGPGAHCPKRMRFGPCGGVRADLSCEVRPVRCPFGTLERPVGWDGPEAPDRPPPALLA
APPVVLTDLTVPPFDRHGLARVVGTLAATCDGLLVGEHHNRPDFPPTQMTGLVRDAGGAP
VVTLTCRDRNRVVLDQELAGLAEAGPAAVFCATGDARGAGVRPEVTQVFDIDGTTLAAHA
AAAGLAVGVPESPEAPPPHLRPGRLAQKQRAGAQFAVLNHVSGPDRLARFAGRARAAGAT
LPLVAGVAVYTDERSATVLDAFPGLHLDPDRVTAVLSAPDPVEAGIAEAVDQARTALRVD
GVVGVNLSGPASARGPVEGAAVKAAVGRALREAA
>A0A011WUZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus albus SY3|TrEMBL
MKTCELFKDKTTLSFEVFPPKSDTPIDSIYSTIDGLAPQKPDFISVTYGAGGNGSNATIG
ICEMIKEKYSIEPVAHLACINLTREKVLFELAQMKAAGIENILALRGDINPNIPPHNDFK
YASELINLIKEQGDFNIIGACYPETHPEADNSIEDIKHLKEKVDAGCSQLISQLFFDNED
FYAFREKAAIAGINVPIEAGIMPVTNPKTIARMASLCHARLPKKFLTIMSKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIASKICAAVQSLFN
>A0A0B6RUI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia plantarii|TrEMBL
MKPIELSLEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGASKDNLRAVLDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFWLEVAAYPEYHPQSRSPKLDLQHFAAKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFTQLMRFSEMCGAEVPRWVARRLESFGDDKESIRAFGTDV
VTAMCERLIRDGAPGLHFYTLNAAMATRAVCERLGF
>G0LI83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloquadratum walsbyi (strain DSM 16854 / JCM 12705 / C23)|TrEMBL
MALGAQSAVDQDGVSNLLRGARFELMPFDSFNDELESLPAGSSIAITTSPQLGIEQTVER
AEEAAAQGYEVVPHIAARYVEDEAQLASIAERLSDAGVNDVFIPGGDREEPAGEFTSAYD
LLEVLDELPYSFEDIGITGYPEGHDFIEDEELAMAMDQKAPHATYIVTQLCYDPETILEW
VESTRERGVDLPIEIGIPGVMNYQKLLQISQKVGVGDSIRFLRKTTGVFEFVRQLIGSRG
VYEPDDLINGLSPYVEDEYYNIRGVHIYTFNQTPDLESWRQTRLA
>A0A3A6DWM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. AM43-5AT|TrEMBL
MKDVREILKKRPLLFDGGMGTYYKAKPGQECEQANLLDPDGILTVHRAYLEAGADAIKTN
TFGLPRMAAAQNPMWEAMADEGWKLAAQAAAKTSAAVFADLGPAPDTESLPAAQTYTALA
ERFAALGAKNFLFETLSSDAGVAEAARQIKEAVPDAFVLVSFAVLPDGYTREGRHCTQLV
RSMTACGAVDAVGLNCVSAPGAMRTLVQQLGRTELPLSVMPNAGYPVVTRTRVQYQGRPE
YFARELARLAAEGVRILGGCCGTTPAHIAALRAALDALPETLPAAPAAAVSTAAKPEVEK
DDAFLRKLNAGKKVIAIELDSPKDADLTGYLDGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGLNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPLTVFGALNLNARNFDVELRRAQEKLQNGMSGFL
TQPVLSAQAVVNLKKTRETLGEKAKILAGIMPVVSQRNAIFMENEVNGIHVDAEIIERFA
GLDRAQGEELGLEVSVKAAQAAAPYADGFYLMTPFNRIALMERLIARLKDEGIAD
>A0A6B3EG53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID11233|TrEMBL
MAEVLASGKPSYSFEFWAPKTPKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRTGTVRA
TQAIAENTTLVPVAHLTAVEHSVAELRHMIGQYADGGVR
>A0A7X1NTL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus terrestris|TrEMBL
MSRISVELVPRSRSGLRAELEAVAQYLPGVDTVNVVDLTRYSTRSWQGCAFARPRYRAIP
HIRAVDLDPDGPLAMVDALATFGIDEVLIVTGDAPADMSARVYDVDAVRAIRRFRRELPH
VRVYAGLDPYRQSLARERDYLERKLEAGACGFFTQPFFDLRLLAAYADLIPQEAEVWWGA
TSVLTLSSLNYWRARNHAVFPRTFAPTLEWNRTFAAELLAFARERRQHAYFMPVKADARA
YLGGIV
>A0A1Q9RB60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MNLLKQALHDRQFVCVMEFVPKPQRLAGFEQLMQRGHLSGWPMLAGIADRVGSNLDLSPL
DTFAALSTPVPVMPHFSGKDRERQDLLAQLERMDQLGLEQLLLLTGDRLHGHEPGQRPVR
YLESVAALSIVRQARPDWLLGAALNPFKYCEEEGGAQYFKAQKKLKAGADFLILQLGFDM
TKYREAMDWMQRQPMPRPMLACIMGLTHGRAKMLEHVAGVTVSPSMKALVAAEEAVSKAH
AKARSVSRLALQVIGLQLMGYAGINLSGVHEMEQLLALERALDDWQGKIRTEEEWALAWA
ESWRMPGVPAVTFHPPGSDWEAGESRVEATTRERLRYHLLSSFHAALFSRSNVLSKAFGW
AVRRPLWSTAPGARLLHRLERGVKRPLVGCDTCGSCRLEDTLYICPETCPKGLANGPCGG
TRLNRCEFGDRECIHSIKYRTAKSVGQTAVLTERLIPCVEVGGRQRSSWPGWFEADARSS
PERIGDTAVS
>A0A4R1HPH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia endophytica|TrEMBL
MDLAQRIEARGSEFLLFALTPPRLTVTREQAQKVADVTQKRLAPVGLDGLVLYDIDEESD
RNPQERPFPFLPTIDPATFRARNLEGWSTPVVVYRAVGKYEESDLRAWLEAQDADHTLTV
FVGASSRDRQSATSLVRAHELWARTRPDLRLGGVTIPERHTRRGDEHLRLISKQEAGCSF
FVTQVVYDVNAAKNLVSDYRYECAARGLDPVPVVFTFSVCGSLRTLEFLGWLGVDVPRWI
QNDLRHVADTLQASYEHSLGAARELIEYCRRMRVPFGVNVESVSIRLAEIEASVALAQQL
ERELRRPR
>A0A1M6JZB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas altamirensis DSM 21988|TrEMBL
MSATSPAQRSNLRVSFEFFPPKSPAMEQTLWSSIQRLAPLEPSFVSVTYGAGGSTRERTH
QTVKRILEETDLAPAAHLTCVDASKGEVDDVVRQYRDTGVRHFVALRGDSQAGAGTAFVA
RPDGYRNGAELTAGLKAIDPSFEISVSAYPEKHPESPDFATDIDLLKRKVDNGASRAITQ
FFFDNDTYERYVERVRRAGIYVPIVPGIVPIHDFTKIQRFCSAIGASIPIWLAERFEGLE
NDPQTRAHVAAAVCAEQVLDLTRRGISDFHFYTMNRADLVYSICHILGMRPRSDAVPAPG
EAAA
>A0A352MNL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp|TrEMBL
AAYPEVHPEAKSAQADLLNLKRKVDAGASRAITQFFFDVESYLRFRDRCAATGIDVEIIP
GI
>A0A415KHX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF37-9|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAQMITSEFNTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPVGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELANKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A3M2LSS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura harenae|TrEMBL
MRRQNPDRAPTIRELLATGEPSFSFEFMPPKTAEAARTLWRTIRELEPLNPTFVSVTYGA
GGSTRDNTVDVVERIATETTMTPVAHFTAVNHSQGELRHLIGRFASAGVRNILALRGDPP
GDPNGEWVKHPEGLEYASDLVRMIRSYGDFCVGVAAFPYKHPRSHDIESDTRYFVEKCRA
GADYAITQMFFRADDYFRLRDRVAGEGCEVPIIPGIMPVTRISTIERSEQLSGAPFPPEV
RERFEAVRDDPEAVRRLGIEHAAGLCRELLDQGAPGIHFITFNRSTATREVYELLEGAGY
GARGSVPPITA
>J2P9T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM21|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPSAPHMSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRALGVTIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A2Z4UBF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia argi|TrEMBL
MKLSDAMREKMLLSFELFPPKTDKGMENLPGTIEHLCKYKPEYISCTYGAGGTNVGKNMD
VCKMIKDAGTIPVTHFTCIGNTAEGIKEQLQNYLDNGVDHMLALRGDLPFGWTGTGGDFA
YATDLVAYVRKEFGDKIEIAVAGSPEGHISCRSLEADIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRCAGITMPVDVGIMPILDQAATINMALSRNACVMPRELCEIISRNWIFPN
PFVKDPFDADVEGKKERFREAGIEYTIRQIDEYRACGIEGIHLYALNKWKDVSEIIDRSG
LRTLV
>A0A2W4YSI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas taxi|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGISFEFFPPKSEKMETQLWEAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPSEKVAAA
>A0A8J3F3Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalicibacterium faecigallinarum|TrEMBL
MTQQNFSIEFFPPKTPAGVEKLRETCAKLGELDPKYFSVTFGAGGSTQHGTLDTVLEIRK
AGHDAAPHLSCIGSSRESLRAILQEYKSHGIKRIVALRGDLPSGYGAMDMSSSEFHHANQ
LVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDVTNFVRKVKAGANSAITQYFYNPDAYF
RFVNDANKAGADVPIVAGIMPITNYANLMRFSDTCGAEIPRWIRLKLAAYNDDADSIRAF
GLDVVTDLCERLLAGGAPGLHFYSLNQAAATHAIWSRLNLSAK
>A0A838WNZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cylindrospermopsis raciborskii CS-506_A|TrEMBL
MQENHTTIHTSNSLTSFREAVQAGEFLITAEVAPPKGGDISHTIAMSATLKGRVHAVNIT
DGSRAVLGMSPLAVCAILCQHGIEPICQLACRDRNRIGLQADLMGAHALGIRNVLALTGD
PVKAGDHPDARAVFDLESVRLLQLITNMNQGLDFNHRTLVDGGLDLFAGAAVDPQSKSWS
GLQSRFERKVQAGAQFFQSQLITDFEKLEKFMDKIASSYNKPVLAGIFLLKSAKNAQFIN
KMVPGVNIPDHIIQRLAKAKYPLEEGMKIASEQVRMAKDLCQGVHIMAVKKEEAIAPILD
LAGVSR
>A0A7X5UD63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter anthropi|TrEMBL
MPAISFEFFPPKTDEQRDQLDKTVRKLKQHAPDYVSVTFGAGGSTLSYTNETVKSIRSEH
GLSVAPHLSCMGGTRAEISALLDEYKESGCRRIVALRGDLPSGMASPGHFRYAAELVSFI
RENYGNHFHIEVAAYPEIHPQAENALVDLQHFKAKCDAGADGAITQYFFNPDAYFRFVDD
VTKLGVTIPVVPGIMPIANFSQLRRFSEQCGAEIPRWIVKRMQAHGDDARAIRELGADVV
AGLCQRLLDGGAPGIHFYTINRYRTTEAVLERLS
>A0A6N7X120|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. BL-380-WT-2B|TrEMBL
MTIPEIMKNRMCFSFEVFPPKEGQPLEPLLDTLDHLYAFKPDFISCTYGAGGTNAGRNVE
ICKAIKDSGATIPITHFTCIGNSKDKIRDELRNYLSLGVDHILALRGDFPKGSASTGGDF
NYANELIAFIKEAFPEFSIAMAGDPEKHFEASSFDEDIAHLRIKQDAGADFIMTQLCHDV
AHYEWWVEKIQKAHITLPVDVGIMPVLAKDPTIRMAVSNGSSIPRDLAEIIARYGDNPED
FKKAGMEYTVKQIHRFISAGIDGLHIYSLNKWADISEIVRAAGIR
>A0A7X5U966|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter anthropi|TrEMBL
MKVNPLIYIDKPVTAFSLTDGYSLEVSARAVPILAANAAGIPRGSMVSVPWLPGESNDAR
LAAIRTIRELGFQPMPHLAARRIASRVELEAFIQRAVVEGGIERCFVIAGDPATPKGPFA
DSYSLIETGVFERAGIKVVGVGGHPDGHSIMSEADRWDVLERKYQAIVSRGMAPLIITQF
AFDADLVLAWLGALRERGIAHPVRVGVPGPAGVAVLARYAALCGVSACASMWASYGLSLG
RLLGTAGPDHFVDRLAAGLTAAHGDVQLHFFPFGGVAQSVEWIGRYRARKGTAP
>A0A4Y9PR51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. CT_GayMR20|TrEMBL
MRDRGLNVRDGATRNSLRRAFDDLGYEVIPFKKTEQAVLDNVPKDVRLTVTASPAKGQDV
TIDLSVSLVGHGYTVAPHLSAQQVRDRAHLADVVARCREAGITDVFVVGGDPTDEPTEFR
HAHDLLVALHELDHGFTDIGIGGHPEGHPTASTETLFQALKDKAPLATHIKTQIVFDPAV
ILKWARELKNRGIDLPVHVGVPGAVHRQKLMRVSGGLGIGESAKFLKKQQSMFWRFFIPG
GYSPNKIIKGLAPHMGKPDNNLEGFHVFTFNDLGPTEAWRQRMLADLA
>A0A1J4SHK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrionaceae bacterium CG1_02_65_16|TrEMBL
MRIADLIPTRRPFLSLEFFPPKERDTWPQFFAEVDKLKALNPLFVSVTYGAGGGTQANTL
DVVTHLKREMGLTPMAHLTCVGASSQALHGFLKAITEAGIENVLALRGDPPKGVTDFRFE
DQEFQHASDLVRFIRASFPDMGIGVAGIPTMHPESATLDDDLKWLKHKVDCGGQFVVTQL
FFENDLYLNYVARLRKRGVTVPVLPGIMPILSMKSAEFIAGLNGRAVFGGFYETLQAAFL
KGGDEAVRALGLAHASRQVQGLIDSGVPGVHLYTLNRAEACLEIINNINLR
>A0A1M6BQ12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium terrae|TrEMBL
MKVTQHIEKANGKTLFSFEILPPLKGQNIQCIFDGIDPLMEFNPPFIDVTYHREEYEFKE
LENGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKAEKEGNAYASELVKQISDLNNGLYLDADLQNSNATDFCIGVAGY
PEKHMEAPSMDSDIYFMKQKIKNGADYIITQMFFDNQKFFEYVEKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNDAVKQIGIEWCIAQSKELVKAGIPVLH
YYSMGKAENIKAIANEVF
>A0A0M1YXU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira santarosai str. AIM|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSRLDPDFVTVTYGAGGSTRSK
TAQILSEISKNYSFPTVSHFTCVGANQEQILKTLKEIRSSGIVNLMALRGDPPKGEGQFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPNAKNLEEDVENLKRKVDAGADFLVS
QLFFVNSIFENFLNLVRAAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A560GME8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirillum amazonense|TrEMBL
MTIVNESADTDRALGGGEPLVTVPRDLRVSFEFFPPKTEKMEQTLWQAIHRLAPLSPAFV
SVTYGAGGSTRERTHATVTAIQQQTGIPAAAHLTCVAATKEEIDTIARAYWDAGIRHIVA
LRGDPPQAADGSGGLGGSGYQPHPGGYAYATDLVAGLKRVADFEISVACFPETHPEAASA
AADIDNLRRKVDAGATRAISQFFFDTDKFLRFRDRVAAAGIDIPIVPGILPITNFGRAVE
LGAKCNCAVPAWMADLFGGLDAEPETRQLVAATVAVQQCLRLEREGVRDFHFYTLNRADL
TVAICHMLGVRAPKVA
>A0A2N0MJ75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G9|TrEMBL
MVKITEGSYEATGHTCFICDFSPPRAGDAGILNQAAIDADFISVAYNPGRAVRVNSAMLA
AAIKQHVGKEASFTLATRDMNKVALQSQLLGAQLLGLENVIVVQGDPFSPRDLERVKAAA
DVTPTELIAAIAGMNQGRDFRDSQLRGPTDFCIGATVDLSRNLAKEAGLAGRKSKAGAHF
FITQPIFDVADAEGFHRAYSQATGEALALPVFFGLQILEADGVIFNSVPQEVRDQLEKGR
SGVEIALELFQKFRDGGLNNIYLVPPIRRGGARNYGSAREVLAAVRD
>A0A4T0UR23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. GY 10113|TrEMBL
MDLTSRLSSGQGDLVLFAVTPPRRSTPADRLPEIARATIERLDHLDLDGLILYDIDDESS
RNPTERPFPFSPTVDPATYRAEHLQAWRTPVVVYRAVGKYQPDELRTWLTEQDPRSTLTV
MVGAASSGTSAPVSLADAQALRAQVSPELLLGGVAIPERHSRRENEHLRLIAKQEAGCRF
FVTQVVYDLNAAKNLVSDYRYECESRGLAPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLRHAANPLRASLEQAVVTAVELIDFCRRLGVPFGINVESVSIRREEIEASVELAAQL
TAHVRA
>A0A1F3BA97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon RBG_16_50_20|TrEMBL
MTKLTEILQRKGRLLTTEFLPPKTAKLSDLVGKVLKVATLIDSVSLPELKANEVSVPRFR
MNAIFTALRLRDLTGVETIFHLTPRDYNKNAVAGLLLAAAETNLQNVLVVGGDRYNNKEE
HVLSKNVYDYSGCTSLVKGIRGLESEAELGTSRFCVVVGTDPTVIYTGDRGKAESEVAKL
VERQDAGAELAQTQPVFDMKYFEFLDLAREQGVKIPILVGILPLRGKADSIEIEQRYGIT
IPHEVKSLLKDNGGEAGKVLGLELAAGLMKEGVRCIHIYPREDCEFVTSLARTLSGSNQF
P
>A0A7M2QPI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Viridibacillus sp. JNUCC-6|TrEMBL
MGLLEKLQTQVLTADGAMGTLLYSYGIDYCYEELNITKPEVIENIHQQYIKAGADIIQTN
TYTANAIKLERYGLESSVKEFNESAIAIAKRAAAPGGQFVLGTIGGIRGIRKSEATLDEI
IAALDEQAGYLLAGNPDGLLLETYYDFEELSSVVKHLRKLTDVPIISQVSMHEPGILQNG
LLLNDALHQLEALGADIVGVNCRLGPHHTIQAFEDVELPSKAFLSAYPNASLLDVEDGKI
VYESEADYFGRAGVLLRDQGVRLIGGCCGTTPKHIEAVKKRIADLPPIENKIVKKKKVIE
IKEATPDHHEPLHEKAKRERTIIVELDTPRHLDTTAFIEGAQILNSTGIDAVTMADNSLA
SPRISNMAMGSILKTQNNIRSLAHITCRDRNLIGLQSHLMGLDALGINEILAVTGDPTKV
GDFPGATSVYDVSSLELLQLIKQLNEGISFSGKPLRKKANFSIAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVYTKEKIIEIYEATKHLETPIFIGIMPLTGIRNSEFLHHEVPGI
KLSDEVLERMRATGDDKNLATAEGIAIAKELIDTAAELFNGIYIITPFTRYDMSVELIHY
IQELDQQKVGDHNYVKATN
>A0A6G6WWQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nordella sp. HKS 07|TrEMBL
MNMFSRLKVEAGDMPALVAAFLTRLSIEITPKQIEKVGLLKERLPQGTRVYVALIDPADL
PHQIDAVATIRAAGLEPVPHVPARFVRDQADLDHRLEAFAERGQVRQALVLGGGAPHPLG
SYDAAIQLLETGLFQKHGIAKIGVAGHPEGNPDIAKARGEEALVSALREKQAYLSAHDIE
GYIATQFLFEAAPVAYWASTLREAGVTLPIHVGVPGPATIKTLVKYAAVCGVGNSARFIR
KQALNVTKLLTVSSPDAFVENLAKLHFEKPELGISGPHLYPFGGFDKLLDWVSSRTP
>A0A6I3XFS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia dura|TrEMBL
MADHNFSIEFFPPKTAEGAEKLRATRAKLSELHPKYFSVTFGAGGTTQRGTLDTVLDILA
AGEEAAPHLSCVGGTRDSIRAILGEYKSHGIKRLVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQAKSPQSDLDAFVRKVNAGADAAITQYFYNADAYFQFVD
AAQKAGVTVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTGLGERLLDGGAPGLHFYSMNQAAATTALWQRLVK
>A0A8H7UDT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mortierella isabellina|TrEMBL
VSLHRVFSFYFHPLYFSSSRLKMKVIDKIKKAEEEGRVYWSFEYFPPKTPMGVQNLFDRI
ERMQRFGPEFVDVTWGAGGTSAELTTEIVANAQAVYGIETMMHLTCTNMPKEKVDYALKA
AKDCGCQNILALRGDPPHGQEKWTSVEDGFSNAIDLVKYIRQQYGDYFGIAVAGHPEGHI
DNPDKEDDLRNLKAKVDAGADLIVTQLFYDIDTFLNFVKQCRAIGITCPILPGIFPIQNY
NGLKRVISFNDNHVPQKIWDDLEAIKDDDAAVKEYGIKLSMEFINKFIENGIRGVHFYTF
NLERSTRIILERMGFVPEQATVKPLPWAPSLHQKRTKENVRPIFWKNRTKSYIQRTESWD
DFPNGRWGDSRSPAFGELDGYGVSLKHPKAECLEMWNHPNTVDDVAGLFAKYCTGDLPAL
PWCAQQLDAESEIIRQRLAAINLQGFLTINSQPAVNGVKSSDAVHGWGPKNGYVYQKAYL
EFFVSPEQLDALISKIGKQAEITYYAVNCQGDLKTNNNNHGPNAVTWGVFPGKEIVQPTI
VDATAFMAWKEEAFELWAEWSRLYEADSATHQVLNSIKEQWYLINIVDNNFVVGDGIWKL
FDLEAVGNLASKLSDASVADR
>Q31D28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus (strain MIT 9312)|TrEMBL
MKSKLQQTLEKKSKVITAELMPPRGGNPIRSLKIAQLLKDKVHAVNITDGSRAVMRMCSL
AMSKLLLENGIEPVMQISCRDRNKIALQSDILGANALGIRNILCITGDSVKAGDQQDAKA
VHEFESVRLLQQIQSFNKGIDPTLGKLSDKKTFIFSGAAADPSCRNQRSLENRMKKKKEA
GAGFVQTQMVMKKENLIEFCEKISNPLEIPVIAGVFLLKSYKNALFINKYVPGANIPEKI
LNRLKDAKDPLQEGINIAAEQAHDFINIANGIHLMAVKAEHLIPKILEKADLTLEY
>A0A0Q4J7H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf28|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGISFEFFPPKSEKMETQLWEAIRTLEPLAPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGDPNADIDNL
KRKLDAGASRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKSDVTVAAA
>A0A0F2S482|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp. BRH_c41|TrEMBL
MTTPRISFEFFPPKTLEASFRLWDTIHTLSPLDPRFVSVTYGAGGTTRELTREAVGTLHK
TTGLNVAAHLTCVDASRAETLEIAEQFAAAGVSEIVALRGDPPKGSNGFVAHPEGFADSC
ELISALADTGKFTIRVGAYPEKHPEAVDQKADIDWLKRKIDAGASEAITQFFFEAETFFR
FRDACAAAGINAPIIPGILPIENWVGARKFALSCGTQVPAWLDEAFDKAIRDNRHDLLAT
ALATELCSDLLEGGVEDLHFYTLNRPELTRDVCHALGVTPKVTLRDVA
>A0A1X7DL41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulosimicrobium cellulans J1|TrEMBL
MSVADAVGQAHGGAARPTVSFELMPPRRPDAAPKFWETARRLVATHPDFVSVTYGAGGTD
RATARQVVGRLLQGTPVLPIAHLTCVGASREDVEEVISDFLDEGVRSFLALRGDPPRDQP
DWQPAPDGVRSSTELVALLREVEASRCASDPAVALRGAARPLTIAVATFPDGNPAARTTR
TQEVRRLWQKQQAGASFAITQLFYDASSYTHFVAEARAAGVTIPILAGLLPTTEPVRLRR
VEELTGVRAPQHLLDALDALPDPEAQHAYGIAYSVDLAQRVLDAGAPGLHVYTFNKHRAA
LDLLEGVHLGGGSRGTGGSTSAAAAPLVPDLASGPWVTGTSLPTTGAATHGTPV
>A0A0P7JSJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MSLKDTFKNKTVFSLEVYPPKTPEGTKKLVNALTGIKRIKPDFISITLGAGGSQNNNALE
LSSMIQNDLNIPAMAHIPGIYRSKKEVADFLKELRQHNINNVLALRGDINPNETPVGDFN
HASELAAFIKSQGDFDISGACYPQKHPESIDLVDDTLHLKEKVNNGVGHLITQMVFDNQA
FYDFRQRLELAGIKVPVEVGIMPCTNCNQIKHITELSGLEMPRKFVDIMNKYANNKEAMR
DAGIAYAVDQIVDLVANGVDGIHLYTMNNTYVAKKIWEATHSLFEATNYQLQHPFLSGSE
NQ
>A0A1V5QHF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium ADurb.Bin345|TrEMBL
MKLHAGSRLEKVLKAGHFAVTVEVGPPRGPDPEVMRKKANLLRGVADAYNVTDNQTAVVR
LSSIVGAKLLLDEGLEPVMQMTCRDRNRIAIQSDLLGASALGIRNCLCLSGDHQKSSAAG
KLKGHPGSKNVYDVDSIQLIAILKGLRDEALQEGGDAIKPATPFFIGAAWTPLSPPEKYR
VLRLAKKIEAGADFIQTQAVYDVPRFAEAVAAARSEGLTDRAAILPGVIVPKSAGMLKYM
SENVAGVQVPEELIRRMASASDPKAEGVKLAAELIGALKDIPGIAGVHVQGIEWEEILPE
VIGKAGLLPRPTI
>A0A0N0CQP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MPLQYSFEITPNIDQVNLDGLLKLHPEFISITDRNHDMDNLLQSIQIADYIHANSSVDVV
IHLTGIDKDEKGVQEMVDLMQQHNIHSVLALRGDKLSQNDTAETFPHADRLIEFIKQQYP
HVNISGTCYLNSSDEEMKWLRQKIEKGCTNLISQFSFDANDYVDYLNQNQIDTPIWFGIM
PLISRSQAEKMLSLTHSTAPDELNALMNQYKDEFGEGGVRYTARMINKIKQAGANHIHLY
SLNNAENTEKIINII
>A0A0M9D3U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MRKQTFSVEIEANPGDLRQMKHYLHKWKPDFVSISNLSRYSYEEMVQCARYIQTDLHIPV
VIHLTGLTHTKEQIKKSFNELMDLNIRNFLLVRGNIHHNMHIEDDFNYASDLIKYVNQLD
KDSQIHVVAGCYPDTHVLADSLTEDIKYLKEKVNSGVDSLISLMCFDNNRIYKFLDKSRE
YDIDVPIRIGIMPITDPFKRHYLAHNNIKMPAFSEEEDNLLENGIDYAVNQINDLYEHNV
NGIHLYTHNDWMVSDRVFENIKKTCKGASSNGQQ
>A0A2K8Y3H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. MB-3u-76|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVSAVPHLTCVDASREELKQIAQDYWDSGIRRIVALRGDLP
AGVDTTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIS
QFFFDTSVFLRFRDRAAAAGVDLDLVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRGDNK
>A0A5L4RUX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter upsaliensis|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A7I8E1D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacillus intestinalis|TrEMBL
MKINELLKKRPTLSFEIFPPKNNENDITSIYATIDELAKMNPDFISVTYGANGSTSKNTC
KIASTIKNKYGIESVAHLTCMNNTKDEIKEILEELKKNGIENVLSLRGDYPKDSDGINHG
DFKYASELNEFIEENFPNDFCLSGGCYPETHYEAKNFEEDLLNLKKKVDAGAKYLVTQIF
YDNQYYYRLVREARKIGIHVPILAGIMPAHNPKQLKNIAKMSNCSVPFDLAAMIDRFAGN
PKAGREVGLHYATYQIIDLMTHGVDGIHIYTMNKPEIAKEILKRTEYIRDEFFKD
>A0A4P6PH13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium S94|TrEMBL
MKSILERMKDHPLIFDGAMGTMIYSKGVFINTCYEHLCVTNPKLIRGIHQEYADAGADVI
ETNSFGANRKKLEAHGLAAELEAINRAAVKLAREVAGDEALIAGSVGPVLKAGQVYLENR
AAELEEIFHEQISVLADEGVDFFIFETFSHVQEAQLAAKVARKFDVPVFVSMTVGKEGET
VKGRPVEQIIQILENDTNVDGIGLNCGVGPAAAYSNAERALPHTTKPFIIMANAGLPQEV
DGRMIYMASPEYFTEYAKRMIELGVRGVGGCCGTTPADIATMAKSVKSMTGVKKHVTISS
HTEQTAPEVDIIPLAEKCSFAAKLARGEKVTSVEITPPRSIDLQPMLEKCRKCKDAGIDA
INIPDGPRASARISPMVAALAVEREVGIETVLHYCCRDRNLIGMQSDLLGGYAGGLRNYL
IITGDPPKLGDYPDSTAVFDVDAVGLTQVVNNLNHGIDVGGNIIDPPTGILIGVGANPCA
VEPERELQHFLNKINAGAEYAITQPIFDPEALLRFLDHADARGGNIPVVAGVWPLVSLRN
AEFLAKEVPGVEIPDAILERMSHAKTKEDGRALGIEIAREICETISDRVAGYQVSAPFGI
VDLALQVLK
>A0A094KHY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp. D17|TrEMBL
MRENLFKEALLNPSVFPVTWELVPGRGAKESAQEKTLSLAKQAAESGKICALTLTDNPGG
TPAMSADFMGGEIVKLGIEPLVHFTCKDRNRNQIESQLYALDRAGVRNILVMSGDYPVSG
YGGRPAPVFDLDPIHTLRLMSDMNKGLTYPGIKGNISHQSSDFFPGAVVSPFKATEAEQM
LQYYKLRKKIDAGAQFIVTQLGYDVRKFHEVFLFMKQNGLNLPLIGNIYILPYGAAKMMN
RNELPGSVVTDKLLAELDRERNESDKGEGARILRAARMYAIMKGMGFSGVHIGGHNIKYE
QVEKIISQGEALISQWADLVRYFDYPIPGGFYYFEQDSKTGLNLDKPTTRQSRPLDATVG
LSYGFSRFFHNLMFDPGKKFYGVMKGLSGKVAGTKIESIFRKLEHWTKVVIFDCKDCGDC
ALIDVAYLCPMSQCPKNQRNGACGGSFEGWCEVHPGKKQCVYVRAYARLKKHGEEAQLEK
NIVPPCNWDLYQTSSWINYYLGKDHTSKKQNNS
>A0A7X8RX70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. ERW19|TrEMBL
MAAPLIHPNWDKAPDGITDGFSLEMTAKDEASLRDAAPLIPADTPIAVTFLPGEDVAARV
AATVAVRQLGFEPMPHFSARRITSEDDFEGYLRAVVEQAGVTRCFIVAGDPPEPVGPYFD
TSALIATGAFERSGIKAIGIGGHPEGHPNMTEAECWAVLEKKVAEITARGMAPLIVTQFG
FDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVTN
LLGTAGPDKLVDAFARGLGAEHGKVRLHFYPFGGLTKTLEWIHGYNKKHGIGPGA
>A0A834TMH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Senna tora|TrEMBL
MKVIEKIQALTAADPDRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGS
TADLTLEIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKANGLQNVLALRGDPPHGQ
DKFVQVEGGFACARDLVKHIRAKYGDYFGITVAGYPEAHPDMIGSDGVATTEAYQNELAY
LKSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCK
TKVPAEITAALEPIKDNEEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILM
NLGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSC
NPSYGALTDYQFMRPRARDKKLIEEWAVPLKNVEDILERFKLFCLGKLRSSPWTELDGLQ
PETRIINDQLEKINAKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEK
LDALVNKCKNRPSLTFMAVNKDGRWMSNAGQTNVNAVTWGVFPAKEIIQPTIVDPVSFMV
WKDEAFEIWSRAWACLYPEGDASRKLLEEVKDRYFLVSLVDNDYINGDLFAVFAEV
>A0A497I7S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nanoarchaeota archaeon|TrEMBL
MSKSSSSKFMKTRSACPKRVLNGPCGGMRSDGTCEVLEFKCVFYENYPSELLLDDGFKIK
PRIKHREYFTKLLSRTYERITWIAEIPPKAGITKKLHILRETTEDALSIPDNPLGRTHIE
PTTFAAYLRNLTESEIVVHLTCRDLNRLALKSRILGLDLIGVKHVLALTGDHISPYEGNR
LMGVFDLDSMRLIYMIRLLSDYGLDERGRRITDKVTLHVGGGLNPYLPLEIELSRILRKL
NSGSEFFISQIIFDESYLIPLLKELRREGINVPIFAGFLLQDYDKIVSFTRTSALPLDDV
PKNLDKLIERYLESLRKLRREYKVIGAYVSTLGKLEYLRTWSEYITGSF
>A0A7Y5CW05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp|TrEMBL
MAQPKEKKSRLLGAGEIGVSFEFFPPKSEKMEEQLWLAVNRLAPLAPEFVSVTYGAGGST
RERTHNTVARIVKETNLRPAAHLTCVNATREEVDEVARAYWAAGVRHIVALRGDPAEGVG
SAYQPHPGGYANAAELTAGLKKIANFEVSVGGYPEKHPESKTIQADIDNLKAKVDAGADR
IITQFGFDNTHYLRFLERARAAGIWVPIIPGIVPIHNFRQVAGFAVRTGASVPAWLARRF
EGLEDDSATTHLVAAAIATEQAMDLVDEGVKTFHFYTLNRADLVYAICHLLGLRPLKVAP
LETRKLAS
>R6K677|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:252|TrEMBL
MKISEVLKQDKPTLSFEVFPPKKDTDFAQVEAAATQIAALNPSYMSVTYGAGGSTKGLTI
RLAEEIQKKYDVATIAHLTCVCAGKDSIRQALSDMKAAGIENILALRGDIPRDYEGEVFT
DFAHASELAELIKACGDFCVGGACYPEVHPDSADRNADIEGLKRKVEAGCEYLTTQMFFD
NNIFFNFMYRIREAGITVPVIPGIMPITKRAQVKNAVKLSGCNVPERFKNIVDRFGDTES
AMSQAGVAYATDQIIDLIANGVNHIHIYSMNKPEIAKAIQDNLSEIIKR
>A0A6M8SNR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deefgea sp. D17|TrEMBL
MPNSLHSKIAQRQSGILLYGITPPKANNTPEKIAEIAALQIERIAPLGLDGLVLYDIQDE
ADRTDATRPFPFMATLDPLVYSRDYLAALDMAKIVYRCVGKYAPAQFGADLLAMNDGVSV
FVGAASRQQQVSLTVAQAYALRREVNPHLLVGGVAIPERHLVKNDEHLRVAHKVTEGCSF
FVTQCVYNVEAAKNFLSDYYYACQQTGTAMVPIIFTITPCGSVKTLEFMKWLGISIPKWL
ENDLIHSGDILAKSLDVCKGIFAELLQYASEKGIPVGCNIESVAIRKDEIEASLQLVRDV
QQMFVANQA
>A0A8J4NVJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aptenodytes patagonicus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>K6PRE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermaerobacter subterraneus DSM 13965|TrEMBL
MPFAPDPAPRTLPAVSPGPALPALADGDPSWALAARPVRPSPAGDSPSGGGPAPSQPCPG
APGGPRGTAREEEEPALGTALLPLTEPAAVEGVHLAAIRAGARLVRTATRWASPWWLPST
SPERIEEINLWAAKLARSARELAGRPCLVAGLLGPLPATAAAGGSTEPEAVLEGYRRQVA
GLLAGGVDLFWVEARHPLEAGLALKAVREAARLPVGVLLVGEGEPPDALPSPWLEAFHSA
GWPDALGVATGGGPARAARWLAAVRRAGWSGPLWVTLGRLDDGPEPVARGLAGPKPATQD
TGGWDAWDALRLLGPGWVGGTGPWQPADLEALAGRIQAVHPEPEGPAPALPVLGPLNRTG
SGSGPAGPGAGHPDAGHPDAGKQAASLPAAAHWGRSRPAGAGSLPGATTSGAGGATGPGS
PAPLREKLGRRFVISVELDPPRGPVATKFLADARTVAAAGADAVNVGDSPMARPRMAAWA
GALLARSAGIDAIMHCTTRDRNLMALQADLLAAHALGVRNVLALTGDHPRLGSSGASPVY
DVDSIGLLEVLAALRRGEDPRGNALGAPADFTVACALSPSADDLDQELDRFRRKLAVGVV
DFVMTQPLYELEPLERVLDRLGGCPVPLVMGVMPLHSGRHAHYLHHQVPGISIPARIREA
LDRAGERGLEVGLQLAEEVVEAARPYIAGVYVVISYGKAEPVAEFVRRLRAWLDGPLPAA
AARGPAARSPEEVRHHAG
>A0A1R1BXD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL H7-0331|TrEMBL
MKLDLREALHQDILVGDGAMGTFLYQMGFPVGISYEELNLLKPEVIADVHRRYYEAGARV
IETNTFSANREKLSKYGLEQEVEAINRAGVELARRAVGSDAYVVGAMGSIRAGKRKNVRT
TKLKEDLRQQIEVLLDTQVDGLLLESFLDLEEMLLALKIIRKLSNIPVICQFATEGAGTT
EDGILLNEAFAKLKHYGADVVGFNCRSGPNGLLRSLEKAAASGPELPYSVFPNAGIADYV
DGRFTFAATPEYFAETALKFADLGARIIGGCCGTTPEHIAFMAKALNGYKPDPSRIDKLQ
SDIRDTGLPTVAKGASVESITESVSTAANDTAGLPPAAEPNIIELVKQRHTVIVELDPPR
DLDIDKFMKGAHALKEARIDALTMADNSLAVTRMSNLALGYLVKEQTGLRPLIHIACRDR
NMIGTQSHMMGLHALGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGVAF
SGKQLKKKANFIVGAAFNPNVKYLEKAVQRLERKIEAGADYIMTQPVYDAKLIERIYETT
KHLNIPIFLGIMPLASGGNAEYLHNEVPGIQLSDNVRQRMSDLKGEAGRAMGVQIAKELL
DAAMPYFNGIYLMTPFLSYEMTADLTKYVWEKSESAISTCTL
>A0A1F8QXU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_57_8|TrEMBL
MKAGTNLERVLESGGFAVTAEAGPPKGTNPKLIVRKADTLRACCDAVNITDNQTAIVRMC
SLAGCVLLKQQGVDPVMQMVTRDRNRIALQSDVLGAIALGIGNILCLTGDHQKFGNHPTA
KGVFDIDSIQLVRALKNMRDDKQFICGEPVSGEVPLFIGAVENPFADPFEYRVTRLAKKV
KAGADFIQTQAVFDVPKFAKWMRMVTDRGLDKQVHIMAGIIPIKSAGMAKYMKESVSGVE
VPDDIITRLEQTKDVKAEGVKIALEIVQEVREIPGVHGIHFMAVGWEDIVPDIVGKAGLL
PRPAVPAAV
>A0A246WNP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum robiniae|TrEMBL
MSKHNFSIEFFPPKTAEGAEKLRATRAKLATLQPKYFSVTFGAGGSTQQGTRDTVLEIIG
EGHQAAPHLSCIGSSRESLRAILADYKANGVKRLVALRGDLPSGYGAMSQASSEFRYANE
LVEFVRAETGDWFNIEVAAYPEMHPQAKSPQDDVQNYVRKVKAGANSAITQYFYNADAYF
RFVEDATRLGADVPVIAGIMPITNYSQLMRFSDMCGTEIPRWVRLKLASYGDDTESIRAF
GLDVVTQLCERLLAGGAPGLHFYSLNQAAPTQAIWQRLVKQ
>A0A8J2WRP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Daphnia galeata|TrEMBL
MKPKIDYNSDGGMCSSSASVSGEDTPNERCQSPTDFDYTSGNKSLAEKIRLRIESGEKFF
SLEFFPPRTKEGAVNLLARFERLRLACPLFCDVTWHPAGNPGGDTETSSMTIASAALNYC
GLETMLHLTCCNLSREDVTKHLNRAREMGVRSILALRGDPPIGQDWQPPENGLPYAVDLV
RLIRDLFGDDFTICVAGYPTGHPDASSYEDDLLHLKEKVDAGADFIITQLFFRAETFIKF
VRDCRALGIEVPIIPGVMPIQSYDSLRQIAKLSKLEVPQEITDILAPIKDNDEAIRNYGV
QQAVTLIRELFNAGVAPGIHFYTLNREVATTAILKQLGLWITDPRRPLPWRRAANAKRST
ETVRPIFWSSRPKAYIYRTRHWDEFPNGRWGKSDSPAFGELKDYYLFYLKSKSSKDDLLR
MWGEELCSEQDVWDVFHCYLSGQPNKSGCKITKIAWNDEELSSETSLLQEKLSEFNKKGV
LTINSQPNVNGAPSEDPVVGWGPRGGYVYQKAYLEFFTCQANVQALLKVLPSFPRVNFHI
INSSGTADYTNCHRHRPVAVTWGVFPGREVLQPTVVDPVSFKVWKDEAFALWREQWGKLY
PEGSPSRDLLTRISETYYLVNLVDNDFPRESCLWDLLNAMFAQRQLDNMSDFIQQDSDVH
LSDGFDDLLNMMKRQNSRGDTSYTHYTMEELVEAAHRQEVHSDEIVAANEGHQ
>Q7NMH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)|TrEMBL
MVKSARLETAAERKEFLITAEVMPPKGPDIEAFLEKATLLKNRVHAVNVTDSNRAVMRMS
PLAASALLVQRGIEPICQLACRDRNRIALQGDLLGAEALGIHNILALTGDPVGCGDHPQA
RAVCDLESVRLLRVIGGLNRGFDSAGNALSSPTRLFAGAAIDPQCTSEAGLRSRFRRKVE
SGARFFQSQLVTDFERLAWFMDAIAHESARPVLAGIFLLKSAKNAEFINRNLPGVTIPEG
IIRRLAGACDPLKEGTAIAAEQVAKARQICDGVHLMAIRKEELIPEILDLAGIAPVQ
>A0A7H8R2V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces rugulosus|TrEMBL
MHVGLKLQDQATSGQPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFVDVTWGAGGSRS
QLTCEMVRIAQTVFGLETVMHLTCTDMPRESVDEALEAAYNAGCTNILALRGDPPREKET
WEAAEGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNSDVDQLIDHLKEKVDAGSSF
IVTQMFYDADNFLNWVQKCRAKGVNAPIIPGIMPISTYDSFIRRSKWTKIHIPPDWLEKL
EPIKNDDAKVREIGTKLVSELCRKLLESGHIHHLHFYTMNLAQASRMILEELNLCPSTEA
PLQKPLPWRKSLGLRRRSEDVRPIFWRNRHASYITRTADWDEYPNGRWTDARSPAFGELN
AYGVRLKGTNEQNIKLFGRPKSIKELSDIFIRYLNGKLDRLPWSDSPITSEADSIKQDLI
DLNQRGFITVNSQPAVNGVKSSHPIHGWGPRNGYVYQKAYLELFIPPYLVEELLARIEKN
NDLTYYCVNKSGELRTRTDEGPNAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQLGDDW
AKCHPAESPSRKLIKQVVDEWYLVNIVNNDFHKTHDLFQLFDGLVIKDLDTEIPGIDPLV
DGPTQPAPASKTAKS
>A0A5F2GXA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.220.01.1.1|TrEMBL
MNARQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPVHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWQREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A1W9TXN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_19|TrEMBL
MNLKTPSKLEKVFSQGHIAVTSECGPPRGSESAAIIEKAKMIKDYVDAVNVTDNQTAMTR
MSSLAACIHLKLNGVEPILQMVTRDRNRVAIQSDILGAASFDINNILCLSGDHQSFGDCA
QGQNVHDIDSMQLVQTARYMRDEGKFLGGDDIKRPPNMFVGAAANPFADPFEIRVPRLAK
KIAAGAEFIQTQCIYNLDKFELWMKQICDRGLNEKTYIMAGMTPMKSVGMARYMKNRVPG
MDVPDEIIKRLSGVPKEKQGQEGIDICVEAIQRLKEVKGVKGFHIMAIEWEEKVPEIVKR
AGLYPRPEV
>V5SDR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium nitrativorans NL23|TrEMBL
MTPQTSERKSRLLGAGEIDVSFEFFPPKSEKMEQALWAAIERLSPLCPSFVSVTYGAGGS
TRERTHTTVARIINETALKPAAHLTCVDASREEVDAVAQAYWDAGVRHIVALRGDPASGV
GQSYIPTPGGYQNAADLVAGLKRIANFEISVAGYPEKHPESASLKSDIDNLKAKVDAGAD
RIITQFGFDNTHYLRFLERARAAGIWVPITPGIVPIHSFRQVAGFAVRTGASVPAWLARR
FEGLDEDPATTHLVAAAVATEQVMDLVDEGVKSFHFYTLNRADLVYAICHLLGLRPLRAA
PLEARKAAS
>A0A238VIJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. DSM 44272|TrEMBL
MRNVVLRRTAARAEPSVLSMPVTGTVRELLAADGPTWSFEFFPPKTPEAEPQLWTALREL
ERLRPSFVSVTYGAGGSTREGTVSVTERIASDTTMTPLAHLTAVDHSVAELRHLVSRLAA
AGVRNLLALRGDPPGADPQAEWVAHPQGLNYAAELVELIKSMGDFSVGVAAFPERHPRSP
DFETDVARFVDKCRAGADFAITQMFFRAEDYLRLRDRVAGRGCDVPIIAGVMPVTNARQI
TRIVQLSGQAFPADLAERFAALDGDRPEDKAAVRAFGVEVATELCRTLLAEGAPGIHFIT
MNRSTATREVYANLAQLPATR
>A0A6B2KPW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenobacter sedimenti|TrEMBL
MKHTYSFEFFPPKSEEGMAKLRTTRAQLAQFKPEFFSVTFGAGGTTREGTLAAVLDIRAD
GLAAAPHLSCIGSTRESIRAILDEYREHGIRHIVALRGDMPSGMVEAGEFRYANELVAFI
RETHGDHFHIEVAAYPEFHPQARSADEDIDNFVRKVRSGANSAITQYFFNADAYFRFVDE
AQARGVDVPVVPGIMPINNFGQLVRFSDMCGAEVPRWLRLRMQSYLDDTASIRALGLDVV
TELCDRLMSNGAPGLHFYTLNQAGLVSTICQRLGL
>A0A1B9XWH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum soleae|TrEMBL
MKVTDHIKKANGKTLFSFEIIPPKKGNNIQDLYNNIDPLMEFNPPFIDVTTSREEHLYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIEN
VMALRGDAMSHQKYFEPTKGGHQFATELVGQIKSLNSGKYLHDVIEANHKADFCIGVAGY
PEKHLESPSLQTDLKRLKEKVDAGADYVVTQMFFNNQKYFEFVNAARAIGITIPIIPGIK
PIAVKRHLQLLPQVFKIDLPETLIKSIDDCKTNKQVRQVGVEWCIEQSKELLQAGVPLLH
YYSMGKSDNVKAIAKALF
>A0A1G9IYJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. ok626|TrEMBL
MKIIDHINNAKGKTLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDNGFIPTPNGHAYASELLQHVADMNKGKYLHDDMESAEKTDFCIGVAGY
PEKHFESPNLDTDFKWLKHKVDTGADFIVTQMFFDNKKYQEFVDKCRANGINVPIIPGLK
PITSSKQLISLPKIFHLDIPLELSEAVQACKSEKEVKEVGIEWMINQCNELKAMGAPVLH
FYTMGNPEPTKRIARAIF
>A0A432VC08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudaminobacter arsenicus|TrEMBL
MMRQRDEHPDGVHLPLDPLPGHSSRGRLERILRRSEFAVTAELNPPDSADPEDVYDRARV
FDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAM
GVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRVMRDNGKFLSGRKLTTPPSVFLG
AAINPFAPPYDFRPHRLAKKIAAGAQFVQSQYCFDVPMFRTYMERVRDLGLTDKCYILCG
VGPLASAKTARWIRSNVPGIHIPDAVIKRLEGAADQKKEGKQLCIDIINEVKEIPGVSGI
HVMAYRQEEYVAEIVHESGVLKGRRPWQREARADDQMVADRLEHILHQGESEQPVQMVEK
AAQ
>R7ZLK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lunatimonas lonarensis|TrEMBL
MKITEHISQASKTLFSFEILPPLKGQSLHDMLAGIEPLMEFKPPFVDVTYHREEFIYKQH
PGGLLQKVSTKKRPGTVGICAALMSRFQVEPVPHLLCGGFTKEETENALIDLEFIGVQNV
LALRGDADKSVGRFVAERDGHSFAWELVKQISDMNKGVYLHDETESGFHTDFCIGVAGYP
EKHFEAPSLKYDLKYLKQKIDAGAEYIVTQMFFDNQKYFEYVEKVRAAGIDVPIIPGLKP
ITSLSQIVNLPRTFFLDLPDGLMEELERCKSNADVKEVGIAWAIQQSKELVKAGVPSLHY
YTMSKADATYRIAKEVF
>A0A2D2Q2S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus lividus PCC 6715|TrEMBL
MSVSSFQAACQRGDFLITAEVCPPKGTNPAAMLRQAAHLRGRVHAVNVTDGSRAVLRMSS
WAAAYLLQQHGLEPICQLACRDRNRIALQADLMGIATLGIRNLLALTGDPVKAGDHPHAR
PVFDLESVRLLHLIQQLNQGMDSEHRPLPDGASQFFTGAALDPQSPSWSGLQQRFEKKLK
AGAQFFQTQLITDFDRLEKFMTQVAAGCERPILAGIFLLKSAKNAAFINRAVPGASIPQH
LIDRLAAATDPLDEGITIAAEHIQQARSLCQGIHLMAVRREDLIPKILDRAGIPPLSGAS
PN
>A0A2G5B6Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coemansia reversa (strain ATCC 12441 / NRRL 1564)|TrEMBL
MKIIDKINKALEDDRCFWSFEYFPPRTQQGVMNLYDRIERMCSLGPLFIDVTWRWGGKSS
DLTLELCANSQTVYGVEANMHMTCTNTNFSLIESALAKAKEQGVQNILALRGDLPDGTVE
FDPNVGEFKYATDLVRYIRSTYGDYFCIAVAGYPEGCLGPEDVDRDIEFLKAKQDAGADL
VVTQLFYDVDNFLAWVDKCREAGITMPILPGIMPIQNYGGFKRMTDLCRVKVPQEIWERL
EPIKDDDQAVKDYGIGVAVEMIDKMRAAGVRGFHFYTINLERSTRMVLERLGFVPTVSEV
RPLPWSPSLSEKRARENVRPIFWRNHARSYIKRTELWDEFPNGRWGDARSPAYGELVHEV
QVRLAPAQAERKWGTPESVDDVKALFVRYCRGKLDSLPWSDTPLQSESGVIEDCLAQINA
RGFLTINSQPACNGAPSSDKIHGWGPPNGFVYKKAYLEFFVAPATMQGLLARLDAEPSVT
YHAVSKCGDLITNCAEDSPNAVTWGVFPGKEILQPTIVERVSFLAWKDEAFDFWNAWSRV
YARDSPSAELLRGICDQWYLVNVVENNFQKPSESIFSLFDGLGQALSNGVPAPQIEQQQQ
QQ
>A0A375I239|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium ruminifibrarum|TrEMBL
MDTPSSLTGTGRLRGVQHEYRPDAVTPQDRLDFRPDETIAQLLARTDRPTISAEFFPPRD
DEGQAVLHRSIEQLEPLHPDFVSVTYGANGSSRERTLDAVRDILASTRLRVMGHLTCTGQ
SVDELKAVIDGYGEMGVRHILAVRGDMPGGPLVPWQRHPQGLSNATELVELIKSRGEFCV
GVGAFPDVHQGSTAENDVRVLCDKQAAGAEFAITQLFFRPANYRLLVERLRAAGCRMPVI
AGMMPVTTIRQVDKFAELSGAPLPEEMVARLQSVADDPEQVRLTGAQICAELARELLADG
APGIQFFTQNRSAATRRILAMLEEGRR
>A0A229MN69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. KbaL1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTDIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGICISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7Z9T7T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
RNILALRGDPPADTPELVRPADGFDYAYQLIDFIKQNTGSDMSIGCAGFPEGHIACTESR
EIDWQRLRNKVEHGAQFVLTQLFFNNDDYFRMADYLRNKLGVHVPITPGILPILSSAQIK
RFSALCGASLPEPILTELDKCGDDENAATAFGIEYASQQCEALLAGGAPGLHLYSLNRSK
SVLAIVRNLGLVDR
>A0A2V9YKG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MAGDLLFRLQKSPVLCDGAMGTLLYGKGIFINRCYDELNLSQPDLIGEIHHEYLQAGAEI
IETNTFGANSFRLARHSLTGHVHEINLQGARIAHSAAKSFDAWVAGSVGPLGIRIEPLGK
TSFDEARQCFRQQIAALVEGGIDLVILETFGYVEELHQALLAARDVNPKLPVVAQVTIDE
DGNCLDGSTPENFAPRLADWGADVIGCNCSVGPVAMLDAIERVRAVVNRTPLSAQPNAGM
PRSVEGRNIYLCSPEYMASYARKFVAAGVRLVGGCCGTTPDHIRVMKSALRAGEAKVARV
QMAKPQPVPSAAPTVPMRERSRLGAKLANGEFVTMVEIVPPKGTDIRKELEGARFVKSVG
VDGINIPDSPRASARISNQALSLLIQREVGVEAVLHYTCRDRNVLGIQSDLLGAAAMGIR
NLLCITGDPPKMGNYPDATAVFDVDAIGLVNIVHSLNRGLDIGGNPIGTGTGFVIGVGAN
PGVPNIDEEIRRFEYKVEAGAEYAVTQPVFDLGLLEIFLKRIEHCRIPVVAGIWPLVSVR
NLEFMKNELRVSVPDSVLERMARTSTPEAAREEGVAIAREMLIAVRGLVQGAQISAPLGR
YASAVDVLEALGSAKAVQN
>A0A2V8VVP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPLRDTPFLDAVARGPLVFDGAMGSQLYERGYFITRSFDEANLARPDLVLEIHRDYVAVG
AQIIESNTFGANRELLRRYGAQDRLRDINRAGVRLARQAAGSAAFVAGSVGPTGTMAAKV
TEERRSALESVFKEQIEALLEEGVDLLVLETFIGAGEMEAALKAARSLYAGPIVAQMSFS
EERPSIDGLPPALIADFLRDRGADVVGVNCAEGPAFVFEVAREMLGHGRPVSAQPNAGRP
RRLDERTIYMTTPEYFGVYARRLFQSGVALVGGCCGTGPEHIARVVDAAAMLSGGRVKVE
EAAKTASVPEVGRLPPVPMEDKSVLGAKIARVFRERLAPDGPRLPLTGPESFVVSVEVNP
ETGLDPARSLEAAAMLRRAGIDVVNTADGPRAVARMSNLALALLIRERLGIDPLLHVCCR
DRNLLGLHSDLLGAWVLGIRNLVIITGDPPKMGDYPAATAVFDLDSIGLLRLLDSLNHGV
DPAGKAMQDRTSFLLACGAEPAAHDYERELRRLEEKKRAGAEFVMTQPVYDGKVLRRFLT
DTRSLGLPVLVGLCPLASARNAEFLHNEVPGMQIPAPIRERMARAATPEAGRKEGMLIAR
DMLMQVKDDVV
>A0A2V9IY26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MLKPFLEHLDKAFVICDGAMGTQLYSKGVFLNRCFDELNLSRAPLVREVHQEYLWAGAEI
LETNTFGANRIKLEPHGLADRVRDINISGVQIAQEVAQGSAYVGGSIGPLGIRLEPYGKL
GVEEARRIFAEQIAALVEGGVDLLCLETFTDLREIEAAILAAKELCDLPVMAQLTLEEDG
NSLDGTPPETFGPHLEKLGADIVGINCGVGPQVMLESIERMARVVTRKIAAQPNAGKPRN
FEGRNLYLSSPEYMASYAKRFVRAGVRVVGGCCGTTPAHIRAIRAAVVAAKSGASRIVAV
PAAEPTAPVEVTPVEERSHLGRLILAKKNITVVEMLPPRGVDATSALEAARHLKDAGVDT
LRISEAPRASARMGAIALAVLLERDAGVEPILHYTCSNRRLLAMQSELLGAYAIGIRNLL
LSDGEPIRVGDYMDATAVFDVDSAGVTRLAWGLNQGRDLGGKPIGKPAGFYVGVTVNPLS
LSTDEEIRRLEQKVEAGAEFVITEPIFVPDLLEAFIRRTQHCPVPVIAGIRLLTTARDTE
FLANEVPGVSVPDHVLNRMRAAGTPEREREEGIAIARELVRSMRGIARGIDLSIWNLPYG
SALEVLAGS
>A0A7Z9TAR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MYAECSAHDRPAISVEFFPPKTAKGEESLYNRVLPRLAEANPDFCSVTYGAGGSTRDKTL
SVVDRIQRDFGLVGMAHLTCLTSTSADILSYINEAKAKGIRNILAL
>A0A2V8KVB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MARNPLRECLQSRRFCHVVEIVASRISREARLLEVASQLATTPGVVAGSITSYAGGAPGQ
DPVRVGTAARARGLTPNIHVTCVSKDRQELRHYLETIAGLGLENVFALTGDYPNGANAVF
DLDSVQLITLMNELRRQGLPFWIAAAVSPFKYTEPDCAYQYLKLEKKFTAGADYAITQLG
FDVRKFRELRRYLDERHIQNPVLGNVYVLGLKSAEKMSKGEPPGCWVAPELVEKIRDEVK
AKDKGEAARLERAARMIAILRGLGYAGAYIGGTHNAEHLSWMIERGQILAPRWKELADEF
TYAPKSAFYMFEPGPAAPRKLQGLSDRAVNALWHLLSPTQIPRGSILEKWARAMFAWIDR
LPTMSHFLERAEFAIKSPAFGCEACGNCVLPDMQYVCPQTCPKQLRNGPCGGTNNGQCEV
IPERSCVWVRVYDRAKHAGEIPLLRIYIPPPDRSLKGTSSWINYFLQRDSRPGSPETSAL
SLRPQATKNPRPTWR
>A0A8C4KIJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dromaius novaehollandiae|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDK
WFSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVN
YCGLETILHMTCCNQTKDEITGHLQRAKRLGLKNIMALRGDPAGEEWEEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRIGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKDQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTEQ
>A0A2V8DE06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MQDFLETVEHRVLVCDGAMGTMLYAKGVFINKSFDALNITQPDLVGRVHQEYVWAGADII
ETNTFGANRIKLGSFGLADKLYAINEQGASAGAIGPLGIRIEPWGKTGIDDAREFFREQA
QALVDGGVQLLVLETFRDLNEIGAAIEAVRSVCDLPIVAQMSTEEDGSTLDGTPPERFAP
DLERRGATLVGVNCAVGPAPMLDTIERIAEVTRAKLSAQPNAGKPRDVEGRNIYLCSPDY
MASYARRFVQHRVRIVGGCCGTTPEHIRQIKIAVRGMAPALSGVEGPAVVLSGTLSGSKI
STPAILAPPIARQEKSRLAHALARRTFVTAVELVPPRGYRADAVIERARQLKIRGVDVIN
IPDSLRAGARVSALSLAVLIEQQAGVETLLHYSCRDRNLLGIQSDLLGAHAMGLRNLLLI
TGDPVRIGDYPDATSVFDVDSIGLTNVVARLNRGCDIGGQAIGAPTAFHIGVALNPTTTD
LDQELRRFEYKVEAGAEFVVTRPIFDLRAFELLRKRIQSARLPVIGGVVPLESARHAEFM
ANEVPGIRVPDELLARMRRAEDAESAAREGVAIAREIAMELQGSVQGLQIATASGDTDAA
LAILDGLH
>A0A1G5D2C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. SF-50|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVQLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAEI
>A0A2V9DIY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIDDLNARLADSVLIADGAMGSMLHEVAGSQRCFEELNVTQPEAVAGAQIIETNTFGAN
RQKLALLGLGDQATPFNYRGVKIAREAREAAAREVLIAGSIGPLGIVRQVRELPAVEVAE
IFKEQALALEERGVDLFILETFSDLDELLTAIAAIRSFSSLPIVAQLTFSDEGTTFGGTR
PLDAALRLKEKNVQVIGANCTLGPQSLLPLIGEMAAAGDVRLSAMPNAGFPKRVGDRTIY
PKSSPEYFALFAREAAALGARILGGCCGTTPEHIRALAEAVKTLRPGKGVEVTAPVRAGP
EAKRVAARQPESRLWKKLQAKHFVVSVEIDPPKGVSLDRVFEQVDRIMACGKVDAIDINS
GTMARVGMDALMLAAALEARGVETIPHLTTRDLNIIGLQAMLLGAWSVGGVRNILAITGD
PPSLGDHPETSGVYEIDSVGLAKVLTRLNQGTDWAGKTLGGATNFTIGVAVNPVADDLDY
EVERFLKKVEAGAHFAMTQPLFDPGHWHAFLKRIGGKSPVPALVGIWPLNSYKQALRLNN
EVPGIVIPGAVLKELEAAGAAARDCGFALARRMLEWARSELAGAYLIPPFKRYEEILEVI
S
>A0A063KV93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas fuliginea|TrEMBL
MALSLKEKIVDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQDRPFAFKQTVDPREYSHLLRNLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDL
QNVVLVGSPSSIGDIKLSLPDAYKALAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGITPQRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKLIA
>A0A7W1W7X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRNFRELLGGDGIYVFDGAVGTRFYDKGVYINRSYDELNLTAPDLVREVHTEYVKAGADI
IETNTFGATHHRLLQYSLENKLREINVAGARLARHAAGENVFVAGAVGPLDLRIEPYGPT
SFDEAREMFKEQIAALLEGSVDLFVLETFSDLSEIQQAIKAVRELCDLPIVAQMTIATDG
KTIFGADTEILAGRLDEYGADVIGLNCGVGPTHILTALEKMRAVTTKKLAAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRFIKAGASFIGGCCGTTPQHIKLISDAVRAVSPRQSKAVKP
TTETVKVIDLKPVDVEIIPPEMRSKWSRKIALGEFVTSVEVLPPKGCDAAKTLESIKLLK
TAGVDAVNIPDGPRAQTRMSAQATAILVEREIGIEAVLHYCCRDRNLLGMMSDLLGAAAL
GVHNLLIITGDPPKMGPFPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGRPTAFSIGV
GVNPGAINLEEE
>A0A7W0K7I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRPERRDVTLKPFLDAIDERVLVCDGAMGTQLYAKGVFINRCFESLNLSDPDLVGSVHAE
YVRAGADIIETNTFGANRIKLRAFGLSDKVGAINLEGARIARKVVGDKAYVAGAIGPLGI
RIEPWGKTGVDEAEQYFTEQATALVAGGVDLFMLETFRDLNEIGAAIAAVRRLCDLPIVA
QMTTEEDGNSLDGTPPEQFAPLLLARGAAVVGVNCSVGPAPMLESIERLAAVTEARLSAL
PNAGKPRDIEGRNIYLCSPEYMASYARRFIAQGVRLVGGCCGTTPEHIRQISAAVRRAAP
AAGRAAGQSDTRAISVAAAPHALTPVPREKKSPLAAKLANGDFVFGVELVAPRGLACAEA
LNEAKLLAGRRVDVVTVLDSLRTGARMSALSLAVLVQQQAHVETLLQYSCRDKNLLGIQS
DLLGAHAMGLRNLLGITGDVRTLGDIPDATAVFDVDSVGLTNVLTRLNHGLDVGGQPIGE
PTAFHVGVMVNPAADDLDAELRRFEFKVDAGAEFAVTRPVFDVGAMERFMDRIARFRIPI
VAGLWPFESVLNAEFMANEVPGATVPEPLLHRMQRTKDDGAASQEGIEIAQELGSALRSM
VQGLHVSAPSGRLSLALRTLDRFI
>A0A2V9DPP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIADFEERIQDAVLVADGAMGSMLFEGAGPQRCFEELNSSQPEAVFRVHQAYIEAGAQI
IETNTFGANRSKLAALGLGDQVARINHRGAKIAREAREAAPHEVLIAGSIGPLAIAPEMR
EVPRGEMIEIYREQAQALEERGVDLFVLETFSHIDMLMAAIDAVRSFSALPIVAELTFSS
EGTTLGGTRPADAAALLAQKNVQVIGVNCTLGPQSLLPILEGFAEGRRALSAMPNVGFPT
RVGDRTVYPRSSPEYFALFAREAAAMGARIVGGCCGTTPEHVRAMAGAVRGLKPAQTVKA
ASVSVATPPEKARVVRRDPESGLWRKLKAGEFAVSVEIDPPKGIALERIFEQVEKITASG
CVDTIDINSGTLARVGMDALMLAGALQARGVETIPHVTTRDQNLIGLQAALLGAWSIGGV
RNFLAITGDPPSVGDHPEASGVYEIDSIGLVKVASRLNQGNDWAGKTLGGATNYTVGVAV
NPTAEDLDYEIQRFLAKVEAGAHFAMTQPLFDPEHWHAFLQRIGGRSPIPVLAGIWPLTS
YKQALRLNNEVPGIFIPEPVLKEMESAGTAARERGFALARRMLAWARTELAGAYLIPPFK
RYEEILELFT
>A0A2E3NRW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MSALQFSFEFFPPKGEKGAERLATVRKQLAEVQPAFFSVTFGAGGSTQTGTLETCVDTLT
DTGIPVAAHISCIGSTRERITELLGQYREAGIQRLVALRGDLLPGMTDPGEFRYANELVS
FIRETTGDEFHIEVAAYPEYHPESPTPEADLQNLLRKIEAGADAVMTQYFYNAHAYEDLC
NRLAAHGVTQPVVPGVMPITNYEQLIRFSDRCGAEIPRWIRRRLEAYGDDLDSLRAFGLD
VVTQLSERLLELGAPGLHFYTLNRAEHTLDLWRSLRLPMPASAAA
>A0A1J6Y126|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. AR2-3|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAADLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVEKVQAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A1G3QUS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium RBG_16_67_19|TrEMBL
MPGRGYTGVGIDNILKFAQEARDSRHVYGLSITDNAGGNPALWPDVLVPEIAAIGCDLMV
HFSCKDMNRNMIEARAYAMKRAGITNLLVITGDYPVTGFFGQPKPVFDIDSVTALHYLQE
MNRGLKAGTAAKSLRLEPTDFLLGAVASPFKATEASAVMQYIKLEKKLRAGAHFIVTQLG
YDARRSAEFIRYVRQILRSNIPVMGSVYVLSAGAGRFMNRGEVPGCYVDDRLVADLTGEA
GAPDKGKGARLQRAARQVAILKGLGYNGAHVEGLNLKFGDVTEILQRAEAIGDNWRDHVE
SFDYSPAGSFFLFEGSDTFDFVKNPSAAPLRQTRRPGIASPVFWAMRILHNLVFIEGTPG
YRMMVR
>A0A2V9J742|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MGLASQTGASLLESLKKGEELFSAELRPPRAHSPGLQSMDDWIDTYHSIRRLNVAGFHVF
ITDNAVGRAEEENLRHLVTNLGPDARRSHIIPFLTSKHPLDYCLRYAERAYEQGFRTLVV
LGGDRHDGIPRCVEHAIQLRRIIRRSVPSLILGGWANPHADLSEQTDYLMRGREETDFFL
TQVVSHHDAEAVERFLELIGRRGIEIPGIFGVFYYRSARKSSLDTLRRFFPVPVREIEKE
FEVEELRADDVCARTIRKLRRLGVRRFYVSNLPVADAAARLQTITGLAAEGEGGG
>A0A3N5JXU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MLSRAPALRTFREAVQGERFTLTAELTLARHTTADEVRRQADVLGRYVDAIQVTDNPYAW
VQMSALAAAAILRGHGVDPLPILTCRDRNRIALESDLLGLRALGVTSLVLTRGQRVPKKH
AVQAGGVFDLRGRELIALAASFGGDDAARPGPEFFIGTDARVFRPNGAWPAESLAARAAA
GARFLQTQLCFNVSVLRQYMQALVAAKLTWRYSVIVSLAVLPSAVTAQWVKKNLAGSRIP
KSVIRRLEQAPHPEQEGIRICAEKMQEIAAVPGVSGINLMTTGDAAAIPAAIEASGLRSG
A
>A0A176EWU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp. HI0049|TrEMBL
DPAFVSVTYGAGGTTRELTRDAVATLHKTSGLDVAAHLTCVDASREETLAIADGFAEAGV
NQIVALRGDPPKGSGGFTPHPQGFTDSCELISALADTGKFKIRVGAYPEKHPEAANPGAD
VEYLKRKFDAGAEEAITQFFFEADTFFRFRDDCDKAGITAPILPGILPIENWKGARRFAE
SCGTSIPKWLSNAFEKAEAHDDGRDDLLAVAVATELCSKLIDGGVEHLHFYTLNRPDLTR
DVCHALGIRSQVELRDVA
>A0A0T5ZN67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CSP1-4|TrEMBL
MTLFRRHSALSAAARDALAQALRAPTFELVPLKNALAQAAFLPPAATVSVTASPARGLEA
TIALCEQLQATGFRAVPHLAARMIRDRAHLRDIVTWLEGVGADRAFVVGGDAKEPGAYPD
GLSLLREMGEIGHPLSEIGIPCYPQGHAFIPDAPLLGALRAKAAFASYMTTQLCFDPGAI
AIWLAARRAEGLALPVHIGLPGVAEPHRLLAISARIGVVDTHRFLVKNTRFVARLIRSGG
FYRPDGLLEGLAPLIADPAAGVADLHVYTFNAVEVTEAWRRRYLAALGAALPA
>A0A1F9CZY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_48_10|TrEMBL
MKAGSHLEKVLEKHLFAVTGELGPPKGNDVSVVKRKAELLKGYVDAVNVTDNQTAIVRMS
SIATSSFLIQMGLEPVMQMTTRDRNRIAIQSDVFGATALGIKNMLCLTGDHHTFGNQVDA
KNVHDLDSIQLIDCVRTMRDQGRRLGGEEKIEGEIKLFIGAAENPFGDPFEFRAIRLGKK
VAAGVNFIQTQCIYDMNRFKEWMKMVRDRGLHEKCHILAGVTPLKSGGMARYMAKNVSGI
IIPDEIIDRVVKAKKPAEEGIKICIEQIQELREIEGVHGIHIMAIEWEQMVSKITEMAGL
LPRPKVE
>A0A022G961|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp. SK-4|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYREGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLENFVRKVKAGADSAITQYFYNADAYFRFVD
DVRAQGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A3N0U793|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lonsdalea populi|TrEMBL
MSFFHANHQEALNQSLAELQGHINVSFEFFPPRTSEMEGTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKAIKERIGVDAAPHLTCVDASRGELKAIAQDYWQSGIRHIVALRGD
LPPEGGKPELYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRVPNWMTAMFD
GLDHDPETRKMVGASIAMDMVKILRREGVKDFHFYTLNRAELSYAICHTLGVRPSIAA
>A0A366IYD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella putrefaciens|TrEMBL
MAFHHAQHSQSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPNWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A5EYC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dichelobacter nodosus (strain VCS1703A)|TrEMBL
MSRFPYLVNMIEKSNSLRLSCEFFPAATKIGEKKLAEVRQALSFLNCEYYSVTYGAGGAT
RDQTIALVKTLCREAERAVMPHITCVASHKRAIASLLAQYQKLGIKHLMLLRGDMPSGIY
QLGDIMSARDLVRLVRKQWGDSVHIVVAAYPETHPQAQTQQIDLINFYEKCAAGANEAVT
QYFFNGDAYLRFRDDVVKMGVSIPIVPGIMPITNYVRLARFSDNCGTEIPRWIRTRLESY
QEDSASLLDFGADVVSQLCQRLVSEGVPGLHFYTMNRADALIEIAKRLGWYAL
>A0A2D6R103|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRTENASSQPTKSRLERTLLEGHFALTLEISPPVGPNRAAVERQIDLLRDYADAFNVTDN
QSARVHTSSLAVSIMLKQAGLDPILQVTCRDRNRLGIQSDLLGASIHGISNVLALSGDAP
IWGDHPQTQGVFEIDSINLVRVLRMMRDDQVFENGNEIPKIAPEFFIGAAANPFAPPHDF
RPLRLAKKVAAGAQFIQTQLIFNVPRFREYMKQVVAMGLHEKTAILAGIGPVRSLRTALF
MKDEVAGMDIPNEIVERLKGLDKEEAAAEGVNICLEIAEEVRQIEGVKGFNVMAVSWSSI
LPELATRMGLHPRPDVMDSPIAGLAPENDDS
>A0A0Q8W0Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium sp. Root236|TrEMBL
MPSQDQSLVDAIRGPSPSYSFEFFPPKDDDGEAVLWQTIADLEELEPTFVSVTYGAGGTS
QERTVRITARIAEQTRMRPVGHLTLVAQTRGEIESVLKQYAAAGVDDVLALRGDPKGGPR
APWEPHPDGMDHAIDLVELAKDLGGFCIGVAAFPEGHPDAASIEHDAQVLVDKANAGADY
AITQLFFRASDYFALVERVRAKGCDIPIVPGIMPILNFAQVARMAELSGAELPREVLDQV
EPIQDDKAAVRAKGIELATQLCRDLLAGGAPGLHFITLNRSKATREIFEALRSDGLI
>A0A1F8P2P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_50_11|TrEMBL
MSLQSKLESGKFAISCEFGPIKGTDTHEITENIEILKGKVDAANVTDQQSAVMRLSGLVT
STLCVQGGLEPIFQMTCRDRNRIALQSDLLGAWVMGIKNVLALTGDLPALGDHPQAKGVF
DLDSVTLLQAITRLNEGFDLAGTELKGKPAFFPGAVVKVDSNTEASAELQIYKFEKKIAA
GAKFFQTQSVYDPASFARFMKRVEKFKVPVMAGIIPLKNAGMAKFMNANVAGVHVPDDLI
QKMSAAPKEDREKVG
>A0A7V1LMY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldithrix abyssi|TrEMBL
MKVTEHLEKAKKTLISFEIIPPRRGGDIQSLLKLVDDLAQYNPPFIDITSHAAEVIYEET
PEGIKRKTKRKRPGTLGICALIQKKYNIDAVPHILCRGFTREETEDFLIDLQYLEIKNVL
AVQGDDSGYKKPVPDGRTTNKYASDLVRQVKEMNEGHYLEDNLLDAKPSNFCIGVGGYPE
KHFSAPNLDTDIYYLKKKIEAGAEYIVTQMFFDNKVYFDFVDRCRAEGIDVPIIPGLKII
TRKSNITSLPRTFHIDLPVELSRQILDASADDVAEIGIEWTLKQARELMEHNVPSIHFYV
MQNTTPINTLLDRLIS
>A0A7R9YL36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diacronema lutheri|TrEMBL
RNTTHDTMSEFTTVLIMPDVVRRGLVSDVVGRFERRGFAVIGLKMLNVTRSVAESRYAGQ
PDAATRAAALVEGPCVCVVVYGASAVSTALAMAGDSLAPLTCAPGTIRGDLGSGSSSCVV
EPAADADGARADATRWFGASELTEPVLHKSIKLVDKIAHWVSENGTRPFISFEYFPPKTA
DGVAKLRQTLALMAQQRPLFLDFTWGAGGSTSELTIELCADAYAAHDIEVNMHLTCTNQA
PALCGEALAEAKRKGIRNIVALRGDPPKGQEK
>A0A6P0HZ32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO3H1|TrEMBL
MNRFRNAVKSGEFLVTAEVAPPKGADPTHMIEMASTLKGRVHAVNVTDGSRAVLRMSSLA
ASIILKNNGIEPICQVACRDRNRIGLQADLMGASALGLNNILALTGDPVKAGDHKDARSV
FDMESVRLLQMIAKLNQGIDWNEKALPDGATDLFVGAAVDPQSPSWSGLKKRFERKLLAG
CQFFQSQLISDFDKLEKFMNQIAVDSNKPILAGIFLLKSAKNAAFINKYVPGVDIPEHII
NRLAKAEKPLEEGIKIAAEQVQIASNICHGVHLMAIKREDLIPKILDMAEISPI
>A0A7W7RCT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lipingzhangella halophila|TrEMBL
MSLPDGGAAGLRGTLAAGHFAVTAEVEPPRDCDPEAIGRSAALLRDWVDAVNITDNQGSR
VRMSSLAASLLALRAGLEPVMQLSCRDRNRLALQSDLLGAGALGVPNVLMLTGDHPRFGD
HPEGKPVFDLDGVQLVWAARTLRDDGALMSGGKIATPPAWSIGTVENPFAPPAGFRARRL
AKKVAAGADFAQTQFVFDIEAFERWMAGLRELGVTEHCAVIAGVGPIRSLRALEFMRSGV
PGVVIPGHVERRLRAVPADRVADTGIDLCVETIQRLTAIPGVAGVHVMAFGQERRVPEIL
QRAGVGPATRTKAASTTPEGGNHHDR
>A0A835GPT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spodoptera exigua|TrEMBL
MEVTPDVSEQDIDDLRVEPLFFSVTWHAKTHQCKDLNIAPIKTACLLKSKQKNVLLHLSC
DMMKATYLTELLAKLQENGICNLFLVSGEGFHPTNSDFVNTTEMIKFIRAKTGQYFCIGI
AGFPGCSDEKLRLIKEKVDAGANFILTQAFFDVDAFKNLKDRCEKMGVHVPLIPGVFSFE
TPKQLDGFINMCKVKVSEDLLNAVSDNEKMNRPCTDIIKQLIKQLNTTCNITHYHFFTIN
KLNDVQKLIEGINT
>A0A517NB95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubripirellula lacrimiformis|TrEMBL
MSLISHYKDSRCAISFELFPPKTAQGLESLADNVRRLCEFKPSYFTCTYGAGGSTRGTTL
SVLAKVREITNLPVASHLTCVGSTVEELESYLNEATAQGTDYIVALRGDPPKGTEEFVAV
EGGLRYANELVELIHSKFSNLGIAVAGYPEVHQESPDAKTDLENLKRKVDAGADIIITQL
FYDNIDYFRFRDRCVAAGINVPIVPGILPVTNFKQAQRIATMCKARIPYDLEKAMDATED
ADEQFRIGVEHARMQTVNLVENDVPGIHYYVLNKSDAATALLDGLQLVS
>A0A2W5AF30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sanxanigenens|TrEMBL
MARRTAGPFAGEGRVSLSLEQLAEARRALDAPLFADLSGDAQVSFEFFPPKTEKMELQLW
DAIETLVPLSPRFVSVTYGAGGSTRERTHATVARIARETPVAAAAHLTCVEASKDEIAEV
AEAYWAAGVRHIVALRGDPPVMGSKFAPHPQGYEGAAALVEGLRKLHPFEISVAAYPETH
PEAVSARSDLDNLKRKLDAGATRAISQFFFSADAFFRFRDAAAAAGIDAEIVPGILPVSN
VAQTRKFAAMCGAAIPPWMDRLFEGLDDHPAARQLVAATIAAELSRRLYAGGVRNFHFYT
LNRAELSYAICHLLGLRPGGAAQDKAA
>A0A522DWD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinibacterium sp|TrEMBL
MNASVRPEATFSFELYPPRTPASATALYESLTHLVATDPQFISVTYGANGSSRDRSLEVL
RHILNNTAVQPMAHLTCVGSSYAEASQLIREFLDAGITSFLALRGDPPKGAHEGDNFLGD
LGSAAELVQLIHRVQVEREPFSFHDVPGFPGAKRLRSGEKVTIAVAAFPNGHPRSRSVEQ
DLDTLLAKEAAGANLAITQLFFYADQYLSFVEKARAAGVTMRILPGIMPVTTPRRLARIL
ELTDEPTPVDLERSLAAADTEEQQAAVGIEHARSLAQELLDAGESGLHLYTFNQHEAPLA
VLRGVGLLDQHTKQKEHA
>A0A143B4P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp. DDH964|TrEMBL
MTRKNPLPLPARLVTEIVIGDGAMGTLLYSRGVPLETNFEHLNLVRPELVRQVHEDYFRA
GARLLETNTFGANALRLGSVGLAHRTADINLAGARLARQAAGREGLVAGAVGPLIPPRGE
TSELPREQKRAIFHQQMEALAEGGVDLFLLETFAGLDDLELALAVAAALGLPAIAQMAFL
EGGRTREGVSAEAAAARLTAAGAAGLGANCGSGPRELHQVLQRLAAVSTLPLTAFANSGF
PEYHEGRYIYLATPEYFAAAGRDLVLAGATLVGGCCGTTPEHIAALAASLAGMQPVVRPR
PLAPLPRPAPRPVAAVSEGRWLERRAAGAVVTVELDPPRGFDCSKVLAAARQLAAAGVDA
INLAENPLARIRLGNLALAREIQEATGVEVIVHVTGRDRNLIGLHSELMGAHLLGIRSVL
AVTGDPVAVGGEAGATSVFDLNSIGLLELLAALNAGRNLLGSELGGHSQFLLGAAFNPNL
PSIEGQLRRLEKKLAAGARFVQTQPVYSRTILERLLERTADFGVPVLVGILPLVSERNAE
FLHNEVPGISLPEEVRKRMRGLSGAAGVAAGMAIAEELITAGEGRVAGWYLMPPFGKVEL
ALGLLRRIRAGG
>A0A271M6R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillaceae bacterium SAOS 7|TrEMBL
MNILDRLKHEVLTADGAMGTLLYSYGIDFCYEELNVEKREVIEQIHLEYIKAGADVIQTN
SYGANAYKLARYGLEHRVQQFNKASMQIAKKAASPNGRFVLGTIGGIRGMRKNSVTLTEI
EVAIREQADSLLSEQPDGLLFETYYDFDELTTVLKMVRRLTDLPLIAQVSMHEPGVLQNG
MALNQALHHLEGLGADVVGVNCRLGPHHTIQALEEVVLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGQAAVKLRNEGVRLIGGCCGTTPKHIEATKKALASLPPITEKKVKTKQPII
IKETTVPPTPRLHEKVKTERTIIVELDTPKQLDTNAYIEGAKALHETGIAAVTMADNSLA
SPRVSNLAIASLLKMNHHIRPLVHITCRDRNLIGLQSHLMGLHALGLHDVLAITGDPTKI
GDFPGATSVYDVSSLELIQLIKRMNEGISFSGKPFKQKANFSVAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVFTKEKIIEVYEATKHLPTPIFIGIMPLTSSRNAEFLHHEVPGI
KLSDETLKRMKACEGDREASAREGVTIAKELIDTAAELFNGIYLITPFLRYEMSLQLIQY
IQQLDGKTNERGISHVQPTSN
>A0A4Y6T921|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. NIBRBAC000502774|TrEMBL
MIRKRTKFKLHDISTSPAIAASIEASPAQVLGPASLAGIFPQGVRVYLTDTGQASQDRLV
DAAKHLRDLGYTPVPHLAARRISSRVEFEEQVKRLAGEAGVSDVLVVGGGVATPAGPFTS
SMDMLSTGIFDRCGINQIAIAGHPEGSPDFSDETATAALKLKYDFAERSDAAMRIVTQFG
FDPARFIAWAEGLAASGIDLPVHIGVSGPARITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESVVGPIERHWQANPAGPIRQIHVFPFGGLQNSADWLAGRGSWQTGDADFSTK
RGTVAI
>A0A4S2TIR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. A0958|TrEMBL
MALGTPSTRTDHARTVREMLATGETSYSFEFWAPKTEKGERNLWNALRRVEAVGPSFVSV
TYGAGGSTRAGTVKATQDIAAESTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGPWVEHPQGVKYAADLVRLIKEAGDFCVGVAAFPERHPRSADWDTDIRHFVA
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCDTPIIPEIMPLTSVRQLERFAQLSNATL
PAELKERILAAKDDATAVRSIGIDFATRFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A4S2UDF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. A0958|TrEMBL
MRDQLASGQRTFSFEFFPPRTEAGYKALWEAVRRVEALAPSFVSVTYGAGGSSRDRTVEV
TRRIAAETSLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGDPRGLWTPHP
DGLTYARELVELIGGLGDFGIGVAAFPERHPRSPDWESEIRHFVAKCRAGADFAITQMFF
DAEDYLRLRDRVVRAGCDIPIIPEIMPATDVRQISRFAELSDATVPTGLAQRLHKARDRP
AEGRRIGVEHATALAERLLGEEAPGLHYITLNRSTVTLEIHQNIHP
>A0A2R7S2T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. HMWF010|TrEMBL
FEVLVGVYPEKHPESPSIEHDIEVLKAKVDAGASLAISQFFFDMDAFLRFVDQVRAAGIT
IPILPGIMPVTNFNGLKKMSAACGTAIPSWLGNLFEGLDHDAETRRLIACSVAAEMCAKL
QEQGFEDFHFYTLNRADLVYAICRVLGVRESIAAEEVAA
>A0A2N3VUN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TLI_146|TrEMBL
MLATGETTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRSGTVKATEQ
IAADSTLTPVAHLTAVGHSVAELRNMVGQYADADIRNILAVRGDPPGDPMGDWVRHPEGV
TYAADLVRLIKESGDFCVGVAAFPEMHPRSTEWDTDVRHFVDKCRAGADYAITQMFFRPE
SYLRLRDKVAEAGCETPIIPEVMPVTSVKMLERLPQLSNAEFPPELKERILAVKDDPAAV
RSIGIEFATEFCARLLADGVPGLHFITLNNSTATLEIYENLGLHQQP
>A0A285VFE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromohalobacter canadensis|TrEMBL
MSTREHPLGISFEFFPPNTDAGREKLKGVRDTLAERRPRFFSVTYGAGGSTQARTFETVK
SVRQCGIDTAPHLSCIGSDKGELRERLESFREAGITNLVALRGDLPSGMGGMGELRYANE
LVEFIRDETGDHFQIAVAAYPEAHPQAPSYEHDLQNFVRKMQAGADLAITQYFFSADAYF
HFLERARALGVEAPIVPGIMPISNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIQAF
GEEVVSNLCQRLLDGGAPGLHFYTLNQATPALRVLDNLRCDS
>I4H0K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa PCC 9806|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDSNDKSLPDGSLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDMAGIPPIHN
>A0A2D6K1I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micavibrio sp|TrEMBL
MEVVNKPTISFEYFPPKNEKLAQTLWDSVPKLAAFDPSFMTVTYGAGGSTRDNTIDVATQ
MHEKTGIPIATHLTYINTPRKELYALADHLWEKGIKHIIALRGDMPKDLNWPLDPDADYF
QYTSHFVAALKARQDFEISVGCYPEKHPDAPSLDKDIEALMKKIDAGADRAITQFFFDNN
LYYDFLEACAKMDIKAPICPGLLPIHDFSSMLRFASTCQTTVPDWLVEKFDAVKDNEQDA
KKLATELLIRQSEDLIKNGVNHLHFYTLNKCAITDEVCSALGYQAKAA
>A0A2S6Z4S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. populi|TrEMBL
MDPDTPGLASTITEAYSLEVSARHIAGLAAAAPRIMRGSTIAIPYLPSQDNDARLAAARM
VRTLGFQPMPHLSARRIASREELHTFVRRAVEETGVERCLVIAGDPPAPLGPFSDSLSLI
DTGVFERSGIQTIAVAGHPEGHQSMSATDRWEVLERKCRSIAERGMAPLIVTQFAFDADI
VLTWLQALRAHGIEHPVRVGVPGPAGVAVLARYAASCGVGACASMLSKYGISFGKLLGSA
GPDRFVDRLATGLTEAHGEVRMHFYPFGGIAQTVAWVEQYRSRSARHWAD
>A0A352PV42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacteraceae bacterium|TrEMBL
MSLREKLASGEFVVLAEMEPPKGVDVSAMVAHAARVKNRVDAFVVPEMSNAVMRMSSLGG
CMVLAGKGLETVLQVCCRDRNRLALQADLLAAHALGIANIMAVAGDDPSFGDHHRTRGVY
DIDLMELLEGIQKLEGGRDMAGVELKGAPSFCVGSTVNAGASGGMLDLELQQLDKKIAAG
ATFFMTPPVFDLQTLGRFAKRLGDRPCRILPTVLLLKSAGMASYIDRHLDNVHVPSDIIR
RIQKAGDKIRECVQIARELVMGLRDAGYGGALIATIGWEDKLPSIVEG
>A0A2H2YRT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 31 E 6|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYQPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEEDLKNFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A246AHK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. AJM|TrEMBL
MKITNHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QDNGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADHSFIPTKGGHCYATDLIQHIKNHNEGKFLHEDIETFKSDFCIGVAGYP
EKHFEAPNLNADFKYLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
VSTLTQLNVLPKIFHIDLPDELTDALSHAKSNAEAKEIGTAAMIKQCKELMDFGVPVLHF
YTMGRPEQTKQIAKAIF
>A0A3M3ZRI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. philadelphi|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRSLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VNFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVRIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLQLPR
>X6IEG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L2C054A000|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDTIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A7J6GY32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cannabis sativa|TrEMBL
MKVIDKIRCETNNDNVVFSFEFFPPKTEEGVENLFERMERMVAHNPAFCDITWGAGGSTA
DLTLDIANRMQNTVCVESMMHLTCTNMPLDKIDHALSTIKSNGLQNVLALRGDPPHGQDK
FVQIQGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDAIGPDGLASPEAYQVDLAYLK
SKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFIRMTGFCKTR
IPSEVTAALEPIKDNDEAVRAYGIHLGTEMCKKILGSGIKTLHLYTLNMEKSALAILTNL
GLIEERKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTTGWDQYPQGRWGDSRNP
AYGALTDYQFMRPRSRDKKLVEEWSIPLKSVEDIHEQFKKLCLGKLKSSPWSELDGLQPE
TKIINEQLVKINGKGFLTVNSQPAVNGERSDSPVVGWGGPGGYVYQKAYLEFFCTKDLLD
ALVEKCSRGFSSFTYMAVNKQGHWLANVDQTFVNAVTWGVFPGKEIIQPTVVDPASFTVW
KDEAFEIWSRGWARLYPEVDPSRKVLEEVENSYFLVSLVDNDYIHGDLFAMSFGTSSPAA
IQKYGAVTVTADPKPISGDSIQSL
>A0A7X9SPH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium beijerinckii|TrEMBL
MIKELLKDNILICDGAMGTYYSEITGNDVSYCEFGNLNDKETIKRIHKEYIEAGAKLIRT
NTFSANTYDLGVSLETLMDIIKSGINLAKEVTKNTSVLIGASIGPIKTDNLDEFSNEVLE
EYKYIVDCFLENGIDIFIFETFSNYNYLKKISEYIKYKNTDRFILTQFAVKPDGFTRDGL
SVAKLIKEVRNTKYIDAFGFNCGSGPAHILEIVKKIDIENEIVSVLPNAGYPEIIHERTV
YPNNPLYFAKKVNEIRSYGVSIIGGCCGTNPSYIKQLTQMVNENSNVVNANTKSEPKVKS
FEKKAKNTFKDKLENGEFVVAIELSAPIDTDISRIIDGAKICKENNIDLVTVPDSPMSKV
RADSTIISSKIKREIGIEAMPHICCRDKNTNAIRSSLIGSHIENIRNILAITGDPISDAS
KVETKSVFNLNSFRLIELIESMNEEIFKEDSIYVGGALNLNVLNKEVEYNRMMKKIEKGA
KFFLTQPIYDDNAIEFLKMIKERTNVKILAGLLPVVSYRNAMFLNNELPGVTIPDKYVQM
FSENMSKEEAQEIGVKITVEIGKKLKNIADGLYFITPFNRVNMLIEIIKQINA
>A0A2C1K921|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS040349|TrEMBL
MNFLEDLKSKILIADGAMGTMLYSHGVDRCFEELNLSKPDDVLAVHQAYIEAGANLIQTN
TYGANDIKLSRYGLEDDIRQINKKAIEIAKKAAKESTYVFGTIGGIRTFKKSAHSIEEIK
RNFREQLYLLLNENVDGLLLETFYDLEEMKTVLSIARKETNKPIIANVSLHEAGVLQDGT
SLTDGFSILEELGANVIGLNCRLGPHHMIQSLEEVPIPEKAFLSVFPNSSLPALNEGRLV
YESDETYFKESALKFREQGVRLIGGCCGTTPNHIKAMAGAVANLAPVQTKQVKVAKKSTI
EVQDQQVNSLPPLEEIVREKRSVIVELDPPKKLGMEKFLEGAQALHDAGIDALTLADNSL
ASPRISNLAAGILAKEKTGARTLIHITCRDRNLIGLQSHLMGLHSLGMSDVLAITGDPSK
IGDFPGATSVYDVSSFDLISLIKQFNEGVSYSGKPLGQKTNFSVAAAFNPNVRHLDKAVL
RLEKKIAHGADYFISQPLYSSQQIIDVYNETRNLQAPIYIGIMPLTSSRNAEFIHNEIPG
IKLSDSIREKMAAAGNDKEKARQEGLAIAKDLIDTAFDLFNGIYLITPFLQYDLTVELTN
YIHEKEKQRAERKITHV
>A0A7L3IAB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pardalotus punctatus|TrEMBL
MVNETQHTCSASSSSRSDGSSSGSESSKENSRCSTPVLDADRHERLREKMRRRQDAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPAGEEWEEEIDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFFKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKSSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A1N6HF94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinivibrio sp. ES.052|TrEMBL
MSYTHAGHIDALNQNIADLDGDINVSFEFFPPSTPSMEETLWNSVHRLKALKPKFMSVTY
GANSGERDRTHDIVKSIHDQTGIAAAPHLTCIDASEDELRHIARDYWQNGIRDIVALRGD
LPSPEKKPDMYASDLVRLLKEEHDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAKMTHVRVPQWMHKQYQ
GLEDDPVTRQMVGASIALDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPLAVAP
>A0A0L6DH75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus gattii serotype B (strain R265)|TrEMBL
MKITEKLQKAEKEGRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALKEAKSHGCQNILALRGDPVAGTST
WEPTPGGFMNAVDLVRYIHKHYPGDFCVAVAGFPQGHPETPDTPEGRAQEMEWLKAKVDA
GAEFIFTQMFYDTSIFFDWVKRVREAGINVPIVPGIMPIQNWEKFEKWVQRENIIVPSHF
YEALNPVRGDDEKVRQVGTKLVADMCKTILQHKEAGIKGLHIYTLNLEKGARMLLKELGF
EGRREQIAPLPWRPSLTPSRREETIRPIFWANRTRSYLSRTADWDEFPNGRWGDSRSPAY
GDLDGYPVSIGITAPDAYNLWGHPTTSFDLHTLFARFCRGDLAKLPWSTQPPASETSLII
EQLAKMNELGYLTINSQPAVDGVRSDDKVHGWGPAGGYVYQKAYLEFFVSPDLLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWAHLYPAGSPSRKLITDTMNTSYLVNIVANDFRDGMSIFEPFLLNQTTVGKVVEGV
KGTVEGIVEGVKGVVSA
>F1YW69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter pomorum DM001|TrEMBL
MTGILSTWLSEKRIDRLLSCNSETPILSFEFVPPRTDAMEQRLWQCIRRLAPLAPRSVSI
TYGAGGTTQVGTLSTVLRLKRNTDLIPAAHLTCVGAPREAVDDLARCYRDAGVHHIVALR
GDPSAGAVDDSPRPGGYTYASDLVAGLRRIADFDISVAAYPETHPTALSPEADLDNLKRK
LDAGGTRAITQYFFDSEIYLRFLDRCLAAGITAPIIPGIMPVSNYEQIVRFSAVCGVTVP
AWLRHLFDGTAKNPELRRIVASMVAVEQIRTLQTYGINEFHVSTLNRADLTYAIAHILGV
RPMQTNASHNVTGLLEKTEVSDERETPADFDSTAWAQEGAPPFMLRTLFG
>A0A0Q8UWW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia sp. Root227|TrEMBL
MSCTDARFSFELYPPRNARAAEALPATIQKLAAAHPEFISVTYGANGSSRSSSLEVLRYI
LDNTDVSPMAHLTCVGSSHAEAGQLIREFLDAGIRRFLAVRGDPPAGLAPGETGLGDLHS
SAELVQLIHRVQAERVPYGELAVPGLPASTVLSHREHVQIAVAAFPNGHPTSHGVSQDID
TLLAKQAAGANLGITQLFFHPEDYLSFAQKARDAGVLFPILPGIMPVTSPARLKRMLELS
GEDLPSELAIQLEIEPTEEGQREIGIAWAADFARRLLDGGAPGIHLYTFNQHEAVLAVLS
RIGLLDANASSTTSTRPTDPSTTEREPA
>A0A7L3ECV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetops frenatus|TrEMBL
MVNETQHTCSASSSSRSDGSSSGSESSKDNSHCSTPVLDADRHERLREKMRRRQDAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDVCVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>M0JN31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula californiae ATCC 33799|TrEMBL
MALGTRTVSDSQGVRTLLTSARFELMPFESFDEEITHLPDNATIAITTSPQLGIEKTVEK
TAEAAEMGYDVVPHIAARYVEDREQLESIAERLEQAGITDIFVPGGDREEPAGEYESALD
MLEALEETEYSFEEVGITGYPEGHDFIDDETLAESMAQKAPYATYIVTQLCYDPDAVLEW
VEDIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVEDDEYNIRGVHIYTFNQTPDTEKWRHKRLDS
>A0A1G7P3I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio legallii|TrEMBL
MNIGRKIRAVGAPFCSLEFFPPADAAQLPAFYATVERLRALDPLFVSVTYGAGGARQQNT
LTVTAELARRGFTAMAHLTCVGAEPESIAGFLQALRAAGVDNVLALRGDPPANRPEDKPW
DWSRAHFHHAADLVAFARQREPGMGIGVAAYPAPHPESPSFAEDRRRTAEKLRAGADFAL
TQLFFDAREYEDLVARLRAQGIAIPIVPGILPIQSFDSLRRVLALCGANIPGKLYLDLEA
ADARGGAQAVREVGLAFAVRQIRRLLESGAPGVHLYTLNKADLCLRLAQETGLSHDKACA
PSS
>A0A159Z4X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frigidibacter mobilis|TrEMBL
MTLPRISFEFFPPQTLDASFRLWETVQVLAPLKPSFVSVTYGAGGTTRKLTHEAVTTIGR
NYGLNVAAHLTCVDATRAETLEIAQSYADAGVTEIVALRGDAPKGQARFTPHPDGFADSV
ELIAALADTGRFTLRVGAYPEPHPEAANTAADVAWLKRKIDAGASSAITQFFFEAETFLR
FRDACAAAGITAPIIPGILPIENWDGTKRFAARCGTAVPQWLDEAFITARRDGREALLST
AICTELCDTLLREGVEDLHFYTLNRPQLTRDVCHALGVAPEVSLEKVA
>A0A423D8H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas protegens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAGYNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLLQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLTHFVRKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A4V3C7H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes brasiliensis|TrEMBL
MALGLPSRLPATPAIGELVRGATPTFSFEFFPPKTPAGEQLLWQAIRELEPLRPSFVSIT
YGAGGTTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRNVIGRLAGAGIRNVLAVRG
DPPGDPMGEWVRHPEGVLYAEDLVRLVKESGDFSVGVAAFPYKHPRSPDVEADTANFVRK
CRAGADFAITQMFFEADEYLRLRDRVAATGCDTPILPGVMPVTRMATIERSSQLTGAPFP
PALLARFEKVADDETAVRALGVELCAEMCARLIDEGVPGIHFITLNRSTATREVWQLLAP
VPAAA
>A0A1H7KQW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga rupis|TrEMBL
MKVTEHIAKANDTLISFEILPPLKGKSIDSIYDHLDPLMEFKPAFINVTYHRSEHMFKKR
ADGSFEKVEIRKRPGTVGICAAIMNHYNVDAVPHLICGGFSREETENALIDLNFLGVDNV
LVLRGDAPKNETFFEPDPHGHRYAIELLDQVAHMNNGIYLEEDLQSGVKTNFCIGVAGYP
EKHFEAPNMQTDMSHLKRKVEQGADYIVTQMFFNNQKFFDYVAKCREMGITVPIIPGLKP
LTSKKQLTILPRTFFVDIPDELSSEVLKCKTDKEVEEVGTRWLIQQSKELKEFGVPVLHY
YTLGKPHVIKNVVETII
>A0A5B0IA35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. EV170527-09|TrEMBL
MTTSSASTVTERISVDRPFFAVEFFPPKDDQGEAELWRAIRRLEVLDPAYVSVTYGAGGS
SRDRTVRTVERIATDTTLCSMAHLTAVSHSTDELRHVIGSLAAAGVRNIMALRGDPPGDP
LGEWVAHPEGLEYADQLVALIKRSGPFCVGVAAFPYGHPRSADLDADTERLVGKFRAGAE
FAVTQLFLEPEGFLRLRDRVAAAGFDQPIIPGIMPLTSEKTFRKGPELSGSPLPGALVER
LAPYSGDAAAFRAAGMEVTGELCERLLAEGVPGIHFYCLNRSTATTELVERLGLAPRHEG
ARHSTPA
>A0A1H9NFE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. YR768|TrEMBL
MFSDILSNYSIEATAKDAATIVIADDLPCPAQVYVPYLPEESDAARIDACAMIRAAGLVP
VPHISARRLPSEAALDTLLGALREKAQVDTIFLIAGDLARPIGPFADSLSVIATGLIERH
GVTSVGIAGHPDGHPDVAEDVIWQAMQDKVAALTARGLDSQIVTQFSFDAQRVLDWLRQV
RARGIGQPVRIGIPGPTGVRTLLRYATRCGVTASAGAVAKYGLSLGRLFGNAGPDRFVAD
LQAGLEPTRTGQVHLHIFPFGGFAQTADWLVQAGAAPRGCRAA
>A0A4Q4WP88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus sp. mg162|TrEMBL
MQIQDMIADAERTGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYFGLETCMHLTCTDMGEEKVNDALAKAYKAGCTNILALRGDPPREKEK
WVATEDKFQYARDLVAHIREKYGNHFGIGVAGYPEGCDDNKDEEQLLDHLKEKVDAGATF
IVTQMFYDADNFIRWMRKVRERGINVPILPGIMPIATYASFLRRANHMNCKIPESWMTAL
EPIKNDDAAVREVGKTLVAELCRKIMTAGIFHLHFYTMNLAQATRMVLEELDWLPTTTRP
RKQALPWKQSLGLGRREEDVRPIFWRNRNKSYVSRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKKWGEPKCIKDIATLFVRYIEKDLQTLPWSEAPLTAEADSIREDLIK
LNQRGLLTINSQPAVNGVKSSHPVHGWGPPNGYVYQKAYLELLVPPELFPEMVSRIHNHA
DLTYYAVTRTGALKTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAYRLGKDW
AHCYDANSPSRVLIDKIMDEWYLVNIGESCRPRGSEASQTDAEFTVNNDFHQPRTIFELL
EGLHVDNLDVHNTPVSNGVHNEYNGDAGHTNGSGSAAAA
>A0A417SM15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM05-5BH|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPDLCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A2J7U2Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas protegens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLQQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLTHFVRKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSTSIQAFG
EQVISQMCERLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A1F0DCQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC061C12|TrEMBL
MTTVHPALSFELFPPRSHASCESLLHTIAELEGTNPDYVSVTYSGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDVQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLRNLCQMAGMEVPTDLAYALETATSNAE
LHRIGVDYALNQCCAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEY
A
>T0NLP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia anophelis 502|TrEMBL
MKVTEHIAQSKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGEKYFEPTKGGNRYASDLVTQINDLGKGKFLHGEISGNDTNNSFCIGVAG
YPEKHLEAPSMQYDLKMLKQKVELGADYVVTQMFLDNQKYFEFVKLAREAGIDVPIIPGI
KPLAVKKHLQLLPQVFKIDIPEDLVNAVSQCKNNEAVKQVGIEWCVQQCKELLDFGVPAL
HFYTMGKSDNIQKIVSEFF
>I4BRJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium chubuense (strain NBB4)|TrEMBL
MDLDCPKRMHYGPCGGVRPDGQCEMRAGECVFPDVVPWSGPQPTPSPPSAPRVLTDFSCT
PFDESDVAATAGILAGSADAVLVGEHQNRPDFPPTLMGRLLLEAGVTPWITLSCRDRNRV
VLEQELRGLGSLGVRTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLASSVGMVAAVPET
PTAPPVAARPLRLVEKQRAGASLAVLNHVPFAGMVADFMSRARAAGLSIPVVAAVAVFTD
NVSAAVLQGLPGLTLDPEVVGEVLGAPDPVAAGIEAAVAEARALLSIEGVHGVNLSGSAS
ASGTRIGAEIKAEVGRRIKTELRA
>A0A1I1NJ21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tropicimonas isoalkanivorans|TrEMBL
MTAPHVSFEFFPPRSVEASFRLHETVQALAPFRPEFVSVTYGAGGTTRRLTHEAVSAIHH
TTNLRVAAHLTCVDATCEETLEIVRQYADAGVRDIVALRGDPPKGSDRFEPHPDGFRDTC
ELISALRDTGDFTIRVGAYPDRHPEAASDTADVEWLKRKIDAGADAAITQFFFEADTFFR
FRDACAKAGIDAPILPGILPIENWKNARRFALRCGAKVPAWLDEAFEKAQRDGREDLLSI
AVASELCTQLVEGGVDHLHFYTLNKPHLTQDICRAIGVTPEVHLEDVA
>A0A6A9S3K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula sp. CBA1122|TrEMBL
MALGTRAVSDSQGVRTLLTSARFELMPFESFDEEITHLPDNATIAITTSPQLGIEKTVEK
TEEAAEMGYDVVPHIAARYVEDQEQLEAIAERLEQAGITDIFVPGGDREEPAGEYESAHG
LLEALAETEYSFEEVGITGYPEGHDFIDDETLAESMAQKAPYATYIVTQLCYDPDAVLEW
VEGIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDDEYNIRGVHIYTFNQTPDTEKWRHNRLDS
>A0A849SG04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp|TrEMBL
MNKNIPLSFEFFPPKTEDGINKLREARAQLAKFEPEFFSVTFGAGGSTRDRTMDTVLEIQ
QEGFAAAPHISCISSSKAEIRDLLQAYQAQGINRLVTLRGDVPSGEVSSGDFRYALELVE
FIRAETGNHFHIEVAAYPEFHPEARTPAADLLNLKRKVDAGANSAITQYFYNADAYFRFI
DQCATAGINVPIVPGIMPINNITQLARFSSVCGAEIPRWLKMRLEEYGDDMVSLRAFGID
VVSELCSTLQASGVPSLHFYTLNQAGPVSNIIENITH
>A0A7Z1Z3W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SMS_SU21|TrEMBL
MALGTASTRTDRARTVRDMLASGKTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADTTLTPVAHLTAVEHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDSDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNAVF
PAALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>W7BEC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria cornellensis FSL F6-0969|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARIAAPSL
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIVANVSMHEPGLL
QSGQTLASALQELADLGADVVGANCRLGPYHMSKALESVPLLENAYLAAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRRGLKSIKPVTSKVVHPIL
ELAELDAAEDAGVRLTDKVKEQYTVLVELDPPRTFDTAKFFEGAQELDAAGVDAITISDN
SLATPRISNMALAAILKQEYDIRPLIHLTTRDHNLIGMHSHIMGFHKLGIQDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALVEAGITVPIFIGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREADKSGNGREEGMAIAKEILDAICEHFNGVYIITPFLRYDLSIE
LTKYVQSKEKISEQIT
>A0A6B3MPG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO4A1|TrEMBL
MTNPTKNSFRTAVESGEFLITAEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQQGIEPICQVACRDRNRIALQADLMGINALGISNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFEK
KLEAGAEFFQSQLICDFDRLEKFMDQIAAGTNKPILAGIFLLKSAKNAKFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSAINDLVCK
>A0A6I2T398|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium sp. WCA-178-WT-4B|TrEMBL
MHSPMFTLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGERLVGDFNHASDLV
SYIRSMKPDLTVFGACYPEGPYQSGSLDQDIENLKIKVDAGVTRLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLDALLNRWEDDIQSLRTAGIL
YASEQIADLVSHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A7W6ZW05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leucaenae|TrEMBL
MSSKTENGQHGIRISFEFFPPKSEEAETQLWNTVADLTEWEPDFVSVTYGAGGSTKAPTL
SAVRRMIHETPFTTASHLTCVGATREDTHRVIDDLLAAGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVSALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGANRALTQF
FFDNDVFERYHDRVRAAGVKIPVVPGIMPIQNLTQLKRFAGACGTHIPSWLDERFEGLDD
DADKRADVAADVAAEQIEDLARRGIHEFHLYTMNRSPLVNAVLDRLRIRRKTDARAGAAA
>A0A848E3E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. vitians|TrEMBL
MYPDTPSLASTVTDAYSLEVSATDIPGLTAAAPRIMRGSTIAIPYLPSQDNDARLAAAQS
VRALGFAPMPHLSARRIASLEELHAFVRRAVDDAGVERCLVIAGDAPSAIGPFPDSVSLI
TTGVFERAGIKTIGVAGHPEGHPGMPATDQWDVLERKCRSIAERGMAPLIVTQFAFDADI
VLTWLEALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACASMLSKYGISIGKLFGSA
GPDRFVDRLATGLTEAHGDVSLHFFPFGGIAQSVAWVEQYRSRTAAHIL
>A0A6B0YVX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineaceae bacterium SB0664_bin_27|TrEMBL
MANPDQASSAGEWALHGGESHLRQVLEAGHFAVTAELNAPDSADAEDVYANVAELGDVCD
GINATDGSGANCHMSSVACCALMARAGYEPVLQMGCRDRNRIAIQGDLLGAAALGVRNVL
CLTGDDVSAGDQPEARRVFDFDALHLLRTAQIMRDQGVLLSGRKLTTPPEFFLGAAANPF
VPPQDLRHLRLAKKIEAGAQFIQTQYCYDVPIFEAFMRRARDMGLHEKVYLLVGVGPLRS
ERAAEFMRSRVPGVHIPDAVVDRLAKTPRKGKREEGIRICVEIIEEVKQIEGVHGVHIMA
YRQEETVPEIVERAGILREKPKE
>A0A6N2V5T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum|TrEMBL
MHSPMFTLEAFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDEAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A3D5QER5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flexistipes sinusarabici|TrEMBL
MKISDILSRKERVLSFEFFPPKKVENEHILFESIERLKGWNPDFVSVTYGAGGSTRDKTL
DWTKKIKDDYLLNVMMHLTCIASTREGVINILKELKKSGIDNIFALRGDIPEELDNIEEA
FKDFRYASDLVRLIREVDDSFSIGVAGYPEGHIECPNIGEDIENLKKKIDQGADFIITQL
FFDNRYFYDYLDMLEKYRITLPVIAGIMPIINIKQVIKFTDMCGATVPEYLKNKMMDRSP
EEMLNIGVDFATKQCRDLLENNVKGL
>A0A327UVN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PsTaAH-130|TrEMBL
MLAGGKTTYSFEFSAPKTPKGERNLWTALRRVEAVAPDFVSVTYGAGGSTRAGTVKETQQ
IVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNILAVRGDPPGDPMGAWVAHPKGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVVEAGCDTPVIPEILPVTSVRMLERLPKLSNARFPDVLKERILAAKDDPAAV
RSIGIDFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLGLHHPPRA
>A0A1I5CFA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Formivibrio citricus|TrEMBL
MKPISFEFFPPKTEEGVEKLRNTRKQLAQFHPEYFSVTFGAGGTTQEGTLNTVLEIQKEG
LNAAPHLSCIGSTRESIRAIVDQYKANGIRQIVALRGDIPSGMGDFGEFRYANELVSFLR
EEYGDWFHIEVGAYPEFHPQAPSAEADIRNFVNKVKAGADTAITQYFFNADAYFRFVDEV
MARGVTIPIVPGIMPIQNFSQLARFSEMCGAEIPRWLRLRLQAMGDDSASIRAFGLDFVT
DLSDRLLGGGAPALHFYTLNAAGAVSTICQRLGY
>A0A417NQG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. TF06-15AC|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPDLCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A562R241|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia lurida|TrEMBL
MADHNFSIEFFPPKTVEGAEKLRATRAKLAELHPKYFSVTFGAGGTTQHGTLDTVLEIMA
SGADAAPHLSCVGGTRESIRAILNEYKANGIKRVVALRGDLPSGYGAGGEFRYANELVEF
MRAETGDWFHIEVAAYPEVHPQARSPQADLDAFVRKVQAGADAAITQYFYNADAYFQFVE
SAAAAGVNVPVVAGIMPITNYSQLMRFSDMCGAEIPRWIRLKLASYGDDTASIKAFGLDV
VTDLCERLLEGGAPGLHFYSMNQAVATTAIWQRLVR
>A0A1H3EQT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopenitus persicus|TrEMBL
MTVSALVASSRFAARVGNRPHFTMSLETSTTDDGAATLLADPRFELMPFDSFGEQMAHLP
DGAAIAVTTSPTLGIDATVEWTETASEAGYEVIPHVAARYVRDREHLDSIAGRLREAGVT
DVFVPGGDREEPAGEFESAHDLLVALEELEYEFEEVGITGYPEGHDFLSEATLAEAMDRK
APYASYLVTQLCYDPETILEWIGTIRDRGVDLPVEVGIPGVMNYQRLLGISKKVGVGDSV
RFLRKTSGVLGFIKELVGSRGQYTPDELIDGLAPHAADPHYDIRGVHIYTFNQVPDTESW
RLGRLES
>A0A1I6WAA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yangia pacifica|TrEMBL
MTRPDISFEFFPPRNIEATFRLWDTVQALSPLGPRFVSVTYGAGGTTRELTRDVVATLHK
NSGLKVAAHLTCVDATREETLAIARQFKDAGVNDIVALRGDPPKGANGFTPHPEGFNSSI
ELIEALREAGDFTIRVGAYPDKHPEAPSATADVEYLKRKFDAGASEALTQFFFEAESFFR
FRDECEKAGIDKPIVPGILPIENWKGARRFAEATGTKIPAWVIEAFEKAERDDRQDLLAT
AMCTELCNELLEGGVDKLHFYTLNRPELTRDVCYALGVTPDNKLENVA
>A0A6A2TT40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. B3-WWTP-C-10-D-3|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6L5YAM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyramidobacter porci|TrEMBL
MNNAFEKMLPNFSFEIFPPKRTGSLESVYGTVDALASLHPDLISVTYGAGGSNRDNTIEI
ASTIQNRYMLPAVAHLTCVGSSLEQTDALLAELKEKGVRTILALRGDRRADADFGDGYFK
HAAELVAHIKKNYDFRVLGACYPEKHPEAPSLEADIAHLKEKVDAGVDALITQLFLNNDD
FYRFRDLAQKAGINVPIIAGIMPITQASMLDKVVSLCGASVPPAVRRFVDAYGHNAEAIR
EAGIAYAASQIVDLLASGVEGIHIYSMNKAGVTRQIAQNIHGILYSLRVKKS
>A0A4Y9XLE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fomitopsis rosea|TrEMBL
KSGSRPSALGGITVPIVPGIVPIQTWNGFIKSTSLSQWNGFIKRTSLSQTEIPKKLLDAL
ERYKSNDEKVREIGTKLVAEMCRWILSGPLGIKGHVHFYTMNLEKGTRMLLEELNLVPRI
QTIKLLPAVEKIGRYHLYVPYACPWATRTLIMRKLKELEDFIDVSVICPHIGERGWPFHV
KDLYLRAAPDYEGRFTVPILWDKQQNKSPSCASTQSTSATSSATSLCALPVRRAETTGNV
SPLSTPSSFRPPCMAPAEEEAGRGRLMMLFIPCAFAALAEWCVGSDTSETIVEYFGDATT
SMRTHSAYRLVPINKDAQILRFEDVE
>A0A848M1K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyxidicoccus fallax|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKG
>F9M3Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis SK236|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLQELNEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFAHQPNFEVN
>A0A497ZK78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum discolor|TrEMBL
MKVIEHLEKANGTSLFSFEILPPLKGDTIESIFKNIDPLMEFNPPFIDVTYHREEYVYKE
LGDGLLKKQVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPENDGHVYASELVTQIENLNKGRYLDDDLQNSSKTNFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKNGANYVVTQMFFDNQKYFEFVEKCREEGITVPIIPGLK
PISTKKQLNLIPHRFKVDLPDALVKEVVNCKSNAEVRQVGVEWCIAQSKELQQKGVPILH
YYSMGRSTNIQQIAETVF
>A0A2D9EKM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp.|TrEMBL
MNASRGLSLEFFPPRDENARGKLTKAAKELEVLNPAYVSVTFGAGGSTREGTADAVSLLQ
QAGYDAAPHLSCIGASRPVLDEILQYYRDQGVRRLVALRGDLPSGMGMNKGDLHHAVDLV
RFIREHTGDWFHIEVAAYPEVHPQARGAQADLNHFAEKVQAGANSAITQYFFNADAYYDF
VERAHGKGVNVPIVPGIMPITNHNQLVRFSDMCGAEVPRWIRQRLTDYGDDLASIRAFGA
EVVTRLCQDLLDQGAPGLHFYTLNNASATLAVARQLT
>A0A1K2FS17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. F-1|TrEMBL
MNLAVTAPAAVGTALLDDFSLEMTGKDVPALQEARDSIPQGTRINVTFLAGEDHAARLAA
ARAVRRCGFVPVPHVSARRLPSRAALEEFLAGLAADGTADNVFVVGGDPARPEGPYEDAL
AVIRTGLLERYGVRHVGISGYPEGHPEIAGPALWSALTDKAAAIGTGPFTGDVITQFGFD
AQPVLDWLAQVRARGVDLPVRIGVPGPAGVRRLLGYATRFGISTSASVARKYGFSLTNLM
GTTGPDRFLRDLSDGYDPARHGTVKVHFYTFGGLRTTAEWITDFQRRTR
>A0A1Y1UCE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kockovaella imperatae|TrEMBL
MKISEKLQKAEREGRTFWSFEYFPPRTAQGLQNLYDRIERMRELGPEFIDITWGAGGKNA
DLSNNLVQICQRSIGIECFMHLTCTEMPQEKVTWALDQAKAHGCQNILALRGDPPHGSSS
WKPTPGGFHYAVDLVKYIHKTYPGDFCVAVAGFPGGHPETADTPEARHQEMMYLKEKVDA
GAEFIFTQMFYDTDIFFDWIKRVRQAGITVPIIPGIMPIQNWDKFQTWVKRERIVVPPHF
YEALNPVVGDDEKVRAVGTKLVGDMCKRILANKEAGIKGLHIYTLNLEKGAKMLLQEVGL
EAHREQVAPLPWRPSLAPHRRSESIRPIFWANRVNSYLSRTDDWDEFPNGRWGDSRSPAY
GDLDGYPVSIGISSTEAYSLWGHPTSFEDVCHLFARFCRGDLTKLPWSSNPAASETTVIT
TQLAKMNELGYLTINSQPAVDGVSSEDKVHGWGPAGGYVYQKAYLEFFVSPELLSNLIRR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGCQWANLYPEDSPSRQIIEQVMNTSYLVNIVANDFKDGSSIFEPFDLDMKPSLTNGQTT
NGVTINGSAPTPEQNGDGGIVNGIKKMVDTSVQAVSNGH
>A0A1I6QNA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibacter maritimus|TrEMBL
MKVTDHINKAKGKTLFSFEIVPPQKGQNIQDLYNNVDPLMEFNPPFIDVTTSREEYVYIK
KENGLLEQKMTRMRPGTVGICAALKYKYDVDAIPHVLCGGFTKEETEYVLVDCHYLGLDN
IMALRGDAMKHEPYFKPTEGGNKFASELVSQIKELNKGKYLHNIIETTNKSDFCIGVAGY
PEKHLEAPNMDTDLKRLKEKVDAGADYVVTQMFFDNEKYFNFVDSARKMGINVPIIPGIK
PIAVHRHLQVLPQVFRLDLPEDLINAVESCSDSKQIRQVGIEWAIQQSKELIKNGVPVVH
FYSMGKSDNIKAIAKEIF
>A0A3B7L663|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. JS92-SW72|TrEMBL
MSAQEHPLGISFEFFPPNTEAGREKLVGVRDALAARGPRFFSVTYGAGGSTQDRTLTTVR
QVRESGISTAPHLSCIGSEKQPLRELLARYREEGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSLERDLANFARKMQAGANLAITQYFFNADAYF
HFVERARALGVEAPIVPGIMPITNYAKLARFSDACGAEIPRWIRKQLEAYGDDSASIAAF
GEEVISRLCQRLLDGGAPGLHFYTLNQAEPSLKILDNIVG
>A0A161HEY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodospira sp. BSL-9|TrEMBL
MKTQKQHERTFSFEFFPPKNDEGAKKLKDTWTELAKLEPRFFSVTYGAGGSTQARTLETV
LDIHKNSGVDAAPHLSCIDSTAEQMRGILQLYKDNGLRHIVALRGDLPSGMRDPGEFRYA
NELVEFIRKETGDHFTLEVAAYPEFHPQAPNALKDLQNFKRKVDAGADSAITQYFYTAEA
YFRFVEDCEKLDINIPIVPGIMPITNYKQLARFSDACGAEIPRWIRKRLEAYGEDTASIK
AFGEEVVTDMCAQLLKAGAPGLHFYTMNQAGPIQAIWKNLGLKPEPK
>A0A532VFU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium Ae_b3b|TrEMBL
MIITQQKPFEEIIGFLERSNAVFICGCSECATLCKTGGEEEVKQMKKRLEETGKKGSGWV
VLDPACNILENKKHFRENKAQLSKADSILVLACGNGVQAVSESIDKIVYPGVNTLFLGDI
IRFGQFEERCQLCGECLLDKTGGICPISRCSKSLLNGPCGGSENGKCEIDPDIDCAWQLI
IDRLSKQEQIDRLKEIIPAKDWSTSRDGGPRKLNIREPHHKKAATSKEKKTEEAKTPVSS
VKANSNLRRILDGGEFAVTGELGPPKGADAEVIKKKALYFKDSVDAVNITDNQTAIVRMS
SIAAGVILSQMDIEPVVQMVCRDRNRLAIQSDILGAAALGIRNVLCLSGDHQKFGNHPQA
KNVYDLDAIGLIQVLKSMRDEKKFLSGDSLTVSPQLYIGAVENPYADPYEFRAIRLAKKI
EAGCDFIQTQGVFNVKKFRDWMKIVRDSGLDGKVHILAGVIPIKSAGMARYMRDYVSGVS
LPDEIVSRMEDAKDPKEEGTRICVEIIEQLKEIEGIHGIHIMAVAWENIIPVMVKQVKLW
PRPKIENIRAS
>A0A7V3RIJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-3 bacterium|TrEMBL
MLRERLKKKVITLEVLLPVHIDFKPLVKELEPFKDYIDALNIPSNPLGKLRPDSVCYAHI
LQEELKIETIPHFVARHLTLLSFESQLLGAKALGIENILCVTGDSPVEGRSMFELNSSKL
LEVAKNLRLGLTSARMHIQPIDFCLCTSFNPNVPNIMGEYIKAGEKYKCGAEVFFTQPVF
QPEKFIEIIREIRNRFKGIKIVAGLSFLYTKKKAFSLMKFLGIPYEYIIKIEEIDETILL
FETFQKLKDYVDGFYIIPIGKYSSAVELVKKIRKAFV
>A0A7V5CJR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MPTPRELPQIFKDRVVVFDGAMGSVLHERGITHSRPFEELNLTSPYLVCQVHAEYIQAGA
DAIETNTFAANRFMLARYGLEDKVTELNSTGAKLARSVAGSSIIVAGSIGPLGVRLAPIG
NVTPDDIRSAVSEQVKGLVDGGVDLILLETQNDLDLVCYMLDSIVENCELPIICQFAIGA
DLTTSSGDTLDDIVVRLSDYPVSAIGFNCSIGPEQTIRAVQGLREICNLPISAQPNSGFP
ANVDGRTLFISGAGYFAERGVEIVEAGASIVGGCCGTSPAHIEALASRVKTLSRLAPARA
RAPRRREAVVSAEKCERSPLLRKMTGGFVTVEVTPPKDTNCTALIEKLRPLVDAGISAID
VTDNPMASMHMSAIAFAHIVKEQLGIATILHLTCRDLNLLGMHSALLGAAALGIDGILAL
TGDPASVGDYPGATSVFDVTSDGLAKIINSLNCGLDYVGKEIGQPTNFAIGAAFNPVADD
MEKEIIRLGKKRESGADFLMTQPVFDIEALKTAVTKLPRDWRPPILVGVIPLRSSRHAEF
LHNEVPGINIPGHIREKLASADGDAAKRIGIEYAREIYLAARENFGGVYFMPPFNNYDAV
REVIVGSC
>A0A7Y3CBJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKTDLKWLKKKVDLGAQYIVTQMFFDNQKYFDFVTAAREAGIDVPIIPGIKPIAVKRHLQ
LLPQVFRIDLPQDLIEEVEKCRNNTAIRQVGIEWAIAQSKELKDAGAPVLHYYSMGKSDN
IREIAKAIF
>A0A7C6A8A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-3 bacterium|TrEMBL
PRSGDAKGGLPLISPGFNPPKADFRGFKGAKPLCIDAVSISDSPMAKVRMNPLPLAYRIK
KEIGLDVILHITCRDRNLIGLQSDLLAAYALGIENILALTGDPPSVGDYPYATVYEVTSK
GLIEIVQRLNQGVDGLGNPLAEPTGFWVGVAGNGTPEDLDQELTRLKVKLKAGAGFIITQ
PVFDLTSFRKFLGRIKPFKIPVFAGIMPLTSLRQAEYLENEVPGIKIPMAIKNELKRAVG
NETKVGIAITRDLINQLKDLVNGICLMLPKAKYQLLAEILGK
>A0A6B1AZS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MNPLANILRPSPRAISSPVARAAVSDMTYEVIPLKSLPEAIQQLPPNARVSVTASPVKPL
EDTLDVCAELLDLGHRPIPHIAARKVTDAAHLRSLAARIKQLELSEIFCIAGDAQDAGEY
PDAMSLLRPLLDITAGDISAVGVSSYPDGHAFIDDSDLHRALIDKQELFQEAEIKGHAST
QMCFSTDTIVSWLTSQRGEGLTMPVHLGVAGVVDRAKLIRMGMRLGVGASLRYVQKNRTG
LLKLFSSVGYNPSDVIDPLADEFDSLGIEGLHMFTFNQVAATQRWQQAKLR
>A0A7C5FMB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MNVLKSGSNLEKLLNAGKFVVCGEMSPPQSVDKDSIAKKCSYFKGYVDAVNLTDNQTAIV
RMSSLVSSYYVLQGGVEPIMQMTCRDRNRLAMQSDILGAYALGVRNLLCLTGDYQCFGNH
PQAKGV
>A0A7C2CPZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MGAQRGRQLLERLRETILVGDGAMGTELWRRGFPQGLPPEQANLSAPDLVRTIHRDYLLA
GAQIVTTNTFGANPLRLQRYGLDGQLRDIVANAVRLAREAIAETNADAFVAGSVGPIGRL
KDPLELSDEELGNAYRQLIAALAEAEVDLLLLETFVDLSDLSRAVKVAKQVCDLPVIAQL
AAMDEGERSAEGRAALAVFELERLCIDGIGTNCGISPTRNLSIVQALAKLTDLPITAFPN
LGYAQYVDGRFVYLGEPDEFAKLGEDLWQAGTNLIGGCCGTTPEHIRLLAERLRTKAPQP
RIARRIEVKPEEQPKLKSPMPNFLGKLWRKPIVIVELDPPRGLNYEPILEGARLLARAGV
DAISLGDNSLASVRLSNLVMAFLMQREAGVPTICHFAGRDHNLIGAQSLLMGMAVLGIPA
VLAVTGDPARLAPDIGASSVYDLNSFQLIELLSKLNKGVNWVDAPIGKRTDFLIGAGFNP
NVPNLAAEVKRLKRKVEKGAQFVLTQAVFDPERIKACGQVMEEVGVPIFVGIAILTSARN
AAFWKTVPGVRLPDEVLRRMESAPKERQLAEGIAIAQELIEVALTHCPGVFLVPPFSRAE
YALPLVEFIRSHSWHRFPTGRGTAEVREERH
>A0A1D9PSV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)|TrEMBL
MHIKDMLAEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHYIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVTIPVIPGIMPINTYASFLRRCNHMGCKIPPKWSASL
EAVKNDDSAVRNIGKDLVAEMCRRIIQAGVHHLHFYTMNLAQATRMVLEELNLTPSTQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLENGIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHDP
DLTYYAVKKTGDLQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLQEPFETSENGD
VDGVRFIEPQSVPLTNGEANGH
>A0A318TAZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas faecalis|TrEMBL
MPAIATRPSISFEFFPPKTEEMERSLWEAINRLAPLHPDFVSVTYGAGGSTRERTHATIA
RIIAETDLTPAAHLTCVNASRADIDEVVRRYHEIGVRHIVALRGDPTTGIGTPYVAHPQG
YQTSAELVASIKRTYPEIEVTVSAYPEKHPESRDFDADIDTLQAKIDAGATRAITQVFFD
NELYFRYLDRVRARGITIPIVPGIMPMHNFKQAYGFVTRAGTTVPAWFAAQFEGLDDDPE
TRRLVAATIAAGQVHKLAKHGVDAFHFYTMNRADLVFAISHLLGIRPTGAKKAA
>A0A2D8FU01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIEQANGKTQFSFEILPPLKGQNIQSIFDGIDPLMEFNPPFIDVTYHREEYVYKE
LENGFLQKQVVRKRPGTVGICAAIQNKYDVDAIPHILCGGFSKEDTENFLIDLGFLGIDN
VMALRGDAVKSETYFSPEKDGHSYASQLVAQISDLNNGKYLEEELQNTTPTNFCIGVAGY
PEKHLEAPSMDSDIYFLKKKIAKGATYVVTQMFFDNSKYFSFVEKCRKEGITVPIIPGLK
PIATKKQLNLIPHRFNVDLPDDLIMEVVKCKDNQAASQIGIEWCIAQSKELIEKGVPVLH
YYSMGKSNNIKTIASKIF
>A0A435G3Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.040.01.1.1|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFVDFGVTRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>A0A359F6P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSSGRIEERLAAGFTLSAEFFPPKTPEGFETLEEALQQMAPVRPDFVSVTYGAGGSTRDS
TRDLVVSINQRFDFPAMPHLTCMGHQRQELVDLLDDYAQSGIANVLALAGDPPSDGSPLR
GDFQFASELVELIAARHDMAIAVAAFPEGHPRSTSLAEDRRRVAEKLDVADFGITQFFFD
ADDYFKMCDDLASLGCSKPVLPGVMPMNNPATVRRFAEMNGVMFPEELAAKIEGAALEDR
VHIIEQHFIEMCQALIAGGAPGLHVYCMNRPRPFQLAAELVGRY
>A0A3B9JQE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
KTLFSFEIVPPVKGGNIQELYNNIDPLMAFNPPFIDVTTSREEFVYLKKEGLLEKKLTRM
RPGTVGICASIKHKYGVDTVPHVLCGGFTKEETEYLLVDCQYLGIENVMALRGDAMAGQR
YFEPTPGGHTYAKELVGQIKDLGTGKYLHEEIESAHSSSFCIGVAGYPEKHMEAPSLQQD
LKRLKEKVDAGADYVVTQMFFDNQKYFEFVAAAKEMGIDVPIIPGIKPIAVEKHLQLLPQ
VFSLDLPQDLIDAVSDAKDKAAVRQVGIEWAIAQSKELLAAGVPVLHYYSMGKSSNIEAI
AAEVF
>A0A3B9DZJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIERANGKPLFSVEILPPLKGQDVNATFKTLDPLVELNPAFIDVTYHRQEYIYKQ
KENGLLKRYQVRKRPGTVAICAAIQNHYKIDAIPHLICGGFTKEDTEDALIDLNFLGIDN
LLVLRGDPIKSEKSFVPEVGGHAHASELIEQITALNTGNYLDDELQESHAMDFCIGVAGY
PEKHFESPNLAMDLYYLKKKVELGADYIVTQMFFDNQKYFDFVKKCREMDINIPIIPGIK
PLTTFNQLTSIPQNFYLDLPEALAMEVLKSKDKERIKEIGIEWCIQQCKELIDFGVPGLH
FYTMSNSINTKRIAEAVY
>A0A1Y3Y6K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. An46|TrEMBL
MKLAEAMKEKMLLSFELFPPKTEKGMENLPGTIEHLCKYKPEYISCTYGAGGGNVGANRE
VCQMIKKAGPIPVTHFTVIRNTKEGIKEQLDQYLAEGVDHMLALRGDLPLGETTTCGDFD
YATDLVKFVKDQYGDKFEIAVAGSPEGHIACRSLEADISVLRQKQDNGADYIMTQLCWDM
EQFKRWLDAIRKAGVTMPVDVGIMPILDQAATINMALSRNGCVMDRELSRLISRHWLFPN
PFNPKDAEGKPFDMFYDKKVKEFKEEGIEYTIRQIDEYRALGVNGIHLYALNKWKDVSEI
IERSGLRTLV
>A0A5J6QH25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas lalkuanensis|TrEMBL
MLPSLERPMSQERRYSFEFFPAKTEAGHEKLMATARNLAAYQPDFFSCTYGAGGSTRDRT
LQTVLQLDGEVKVPTAPHLSCVGDSKAELRALLAYYKDAGIQRIVALRGDLPSGMGMASG
ELRYANELVEFIRAETGDHFHIEVAAYPEVHPQARSYESDLANFVRKVKAGASSAITQYF
FNADSYFYFVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADD
AQSIQAFGEQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWKNLNLPR
>A0A150P6T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
QAGALAEGGVDLLIFETFRHLDEIKLAIEAARKAAPGLPVLASMTFDTSGLAADGSEPER
VARTLRDWGVDLLGVNCGDGPQLSLAMAERMATAGLPLCVQPNAGLPRTVDGRLLYMATP
EYFDVFARRMIQAGAAMIGGCCGTTPEHVKWMATTPEHVKWMAKSARMLRGGAAPEPAAR
PHITMDAPTGSEPTPLGERSPLAAKIAAGKFVVSVEVNPAPGLSPDGALSAAKMLIDSGV
DVVNVADGPRATARMTNLAFCALLLQRYGIEPILHVCGRDRNLIGQMAHLLGAHAIGIKN
LVVITGDPPKVGDYPEATAVYDLDSIGLLNMASTMNRGLDPAGKPIPGGKTSFLLATGLE
PGAPDLDKEIARLERKRAAGADIIMTQPVFHQDLLEKVLKRIEHLGMPVLVGVLPLVSHK
NAEFLHNEVPGMQIPEEIRERMRKVPAGPEARKEGVKIAREMLFSVRHRVQGAYLMPPLG
KYELALEVLDGLKTG
>A0A1W1BIH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MFEKFCDVLCLEKEFITVEVNPPHGASIENLIADIKKYNLHEKVTGFTCTDNPLAKLKMS
GVLSAIKIQQTFGKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKLSDQPD
VKGVLERDSTLLLSIIHHLNKGVDYSNKPLTPTPKPIYPFAVSNAYAKNMDSLKKRMIKK
LNYGARAIITQPVYDIDNAKELLKLFKEAKEESIRETAKEAHLVLGQFPIVAARTANFID
DKVPGINVPKKIIDEMNLAAMDGSKKEREVGFALSKHLFDDVMKIHGKVHLMTHNRFDLC
TELIGER
>A0A3B0ZU77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MLIDKIKNRESGIVVYGITPPKHDTSPEKILEISSRQMQRLESLNVDGLILYDIQDEKSR
TAEQRPFPYMATMDAYAYSEQYLEALDIPKIIYRAVGKYSKQELETFLLSASKSNNLTVF
VGAASKSQAVSLSIKEAYELKLQVNKELLLGGVTIPERHQSKGDEHIRVFNKIARGCQFF
VSQGVYDVNASKNFLSEYFYYGQEHNIPLVPILFTLTPCGSIKTLQFMKWLGISFPKWLE
NEMIHSHDILEKSIHASEQNWLELKEFADEKNIPIGCNIESVAIRKVEVDASIELLRRVS
>A0A830FL96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halarchaeum rubridurum|TrEMBL
MAQTTSTSRDSTTLLADPRYELMPFDTFGDQIKHLPDGATVTITASPQLGIERTIEATEE
AVEQGFEAVPHVSARYVRGDDHLAEIAEQLTELGVDDIFVPGGDREEPIGDYESAYDLLQ
GLERIDYDFEDVGITGYPEGHDFLSDETLAESMDNKAPYATYIATQLCFDPNAVLEWIEE
IRARGVDLPVVVGIPGVMKYSRLLSISRKVGVGDSIRFLQKTNGIIGFLRQLIGSRGNYT
PDALIDGLQPHADDPEYNIQSLHIYTFNQVPDTESWRKGRLN
>A0A150R0S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
MVTKSKMERLLSERRFLVSAELTPPRHHDLEKLLKHARNMADHVDVVQINDHLLSQARCA
NMAVGHLVKQEGIEPVLQFSLRHKNKIALQGDLLGMAALGLSNIIVLGGYPCAIGSDPDA
KEVSDVDSMRAIELTRRMTREGKLFNGDVMSPAPYFHVGTIDFPCAEQAIAGAMDRLSAK
IDAGASFIQVQAVFELASMRRWMAAVVERGLHERAHFIAAIFPFAGVDRLSFLQKVPGLV
VPDHLIERVRQSGDAEGESYRITLELIRGLRDVPGLSGIHMRSIGAEDWVPRLVEEAGLR
QAA
>C6DHP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium carotovorum subsp. carotovorum (strain PC1)|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWQSGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTAMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A0H3JZM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)|TrEMBL
MNMRRFREAVAAGEFLITAEVAPPKGADPSGMLAHAELLRSRVHAINITDGSRAVMRMSA
LAATALLRQQGIEPICQFACRDRNRIALQADLLGAQALGLDNILALTGDPVKAGDSPEAR
AVFELESVRLLQLIQKLNSGLDIHEKSLPDGASDLFVGAAVDPQLKSWSGLERRFWRKVD
AGAQFFQSQLICDFDRLDRFMEQIARPSGRPVLAGIFLLKSAKNAEFINRNVPGVQIPQT
IIDRLAAAADPLAEGIANAAEQVRWAQQLCQGVHLMAVRREDLIPAILDQAGIAPLQPSS
DRQSSTLLMS
>A0A1G8V3C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium G41|TrEMBL
MKLTDIYKTKKTVLSFEIFPPKKDDELENIDPTLEILSDLKPDYISVTFGAGGHANNSKT
IALAKRIKEVYHTEPVVHLTGLCYDKEEIDLFAKEIQNAGVENILALRGDINPNVPQKDI
FPHASDLIAYLKESYDFCIAGACYPEIHPESKDRVEEMKNLKKKVDAGAEVLLSQLFFSN
KTFYEFTEICRIAGMDVPITPGIMPALNAAQINRMVTMCGATLPHSFQKIIERFGNNKEA
LFDAGMSYALSQIIDLLANDVDGIHLYTMNNPVVAKKICEGVKNIVNA
>A0A3B0RG87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MTPKPNQPGLFATQPKDINVSFEFFPPKSEKMEQALWSSIAKLAPLNPAMVSVTYGAGGS
TRARTHATISRILTETDLVPAAHLTCVGASRGEIDDIAREYQDMGVRHIVALRGDMPTIG
QPYAPHPEGYVNGADLVNGLKKIGDFHLSVAAYPESHPDSVDQKADIDNLKRKIDAGADQ
AITQYFFDVDMYFRFMDRVLAAGITVPVIPGIMPVTNFAQARNFSARCGTSIPSWLESLF
EGLDNSPEIRRHVAATVAAEQCMRLYQGGVKDFHFYTLNRSELTATICHFLGVRPEGEQ
>A0A3B0VQU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MIVAERKPLAEILEMVKDCKKILVLACRGCVTVCSAGGEREAEILASLVRLGLKKNGCRA
EVIEGSLVRQCDKEYIDAIDEWQGRYDAILSTACGVGVNFIANLRPTDNVYPALNTTFFG
GSAEQGVWSEQCAGCGNCVLHLTGGLCPVARCAKSLMNGPCGGSVDGRCEINPSVDCVWQ
MIYDRMGRLDRQQELTVAAPIRDWSTAGHGGPRKRIRGDLTV
>A0A374RVJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. TM05-37|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRSHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDASASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A3N4RCF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. BIGb0102|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GQGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A095YT07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. S6-Spd3|TrEMBL
MTQPSQSSSDLTTLSFEVMPPRKENLIKPFWDTVQRLLSVTPDFLSVTYGAAGQDRHSAR
DVVRSLVQDSPVQPIAHLTCVGTTATEVGEVVSDYLDAGVRTFLALRGDPPVGRPDWQPA
PGGVSSATELVTLIRSIEAARCAQYPGAALRAAFKPLTIAVAAFPAGNPAAGTSPNQEVE
RLLVKQSAGASFAITQLFWETDTYVNFLEKARSNGVTIPIVPGILPPTDIKRVNRMTELT
GVVFPEYLRRRLESAQSVEEMYSVGVSLGARLARDLHEVGAPGIHMYTFNKAAPALDVLD
AAGLVSASHLDPSISR
>A0A3B1CMR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MRIAELMKNSDQFISLEYFPPKERSAWPNFFSVVEKLTAVDPLFVSVTYGSGGGTQANTL
ELVTRIKKDFELEPMAHLTCVGASADKLSGFLDSLVKEDIDNVIALRGDPPKGDTKFVAE
NEKFQHASDLVSFINKEYPAMGVAVAAYAEKHQEAESLDQDIRYLKHKLDLGSDFAITQL
FFDNDLYWSFLARARAEGIDKPVIPGIMPIFNLKLIRKIVSLCGAKIPDSLLKELEKADK
SGDEKGVEKVGIEYARAQIKDLLAKGAPGVHLYTLNKAKGCLAILEGLL
>A0A133RY64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MTMSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLA
DFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYA
TDLIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERF
YDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLR
AAGLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1G3Y2Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfovibrio sp. RBG_19FT_COMBO_42_12|TrEMBL
MTFYESLNSGKFVVTAEVGPPKGTDIKETLHHMELLKGKVDAANVTDNQSAVMRICSIAI
CKLAIEHGLEPIFQMTCRDRNRIGLQSDLLGASVLGIKNVLCMTGDHVSAGDHKNAKPVY
DVESVQLLQIVDGLNNGKDMSGNELKGATDFFQGAVVTPEANPIEPQLMKFEKKVKAGAR
FFQTQAIYDIEKFKEFMKFAREFPVKILAGFVILKSAGMATFLNKNVPGIRVPQELIDEL
KAAGKEKALDTGLNIAARQIKQLKDEKVCDGVHIMAIGMEDKVPIIMERAGLL
>A0A7J0ADZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium|TrEMBL
MESDIRYAKEKVDNGAQYLVTQMFFNNEKYFSFVDRCRAAGINVPIIPGIKPVVQLSQLS
VLPRVFRSEIPEEFASELRKAKTDDEAAEIGIEWSIAQCRELIRHSVPGLHFYTLLASDS
VRKIAKEIF
>A0A7X1FAR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium aerophilum|TrEMBL
MTVPIIHPNWAVPARGLTDGYSIEITAKDVSALREAAPAMPVDTPVAVTFLPGELQGDRI
AAAVAVRALGFEPMPHFSARRLVSVAEFEDYLGAVVEQAQVRRCFVVAGDPPEPQGPFFD
SMALIDSGAFERNGIKAVGVGGHPEGHPVMSPEQCWQVLDAKIAAITARGMAPLVVTQFG
FDPDALLGWLAEARVRGIDAPVRIGVPGPAGIKRLIAFAARCGVGASASVLKKYGISLGN
LLGSAGPDRLLDAFAAGLGEEHGRVRLHFYPFGGVGRTVEWIGDYERRHGLDRPR
>A0A8F8II67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. L51/94|TrEMBL
MTSTPDTGRSDVSISFEFFPPKTPDMEGQLWAAITELTEWQPEFVSVTYGAGGSTKAPTL
NTVRRMIAETPLPTASHLTCVSATREDTHRVVDELRAAGVRHFVALRGDPPGGIGTAYQP
HPGGYENAAALVAGLRDIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDVFETYMERVRAAGIAIPVLPGIMPIQNLTQLKRFAGMCGTSIPSYLDERFAGLDD
KPEERAKVAADVAAEQIEDLVRRGHREFHLYTMNRAPLVGAVLERLGFKRTKIAEAAGAA
A
>A0A365ZXE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella sp. PE36|TrEMBL
MTSVIERLRGDTPVFSVEFFPPRDEADEAVLWRAVRELEQLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGEWI
PHPQGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSPDLDTDTRYLVRKFKAGADFGIAQ
LFFEADDFLRLRDRVAAAGCDKLLIPGIMPLTTPRTLHKTIELSGVDAPRTLLDRLEPLS
ADAKAFRAEGLDAVTELCERLLAEGVPALHFYTFNRSKATRELVGRLGLVPARA
>A0A2T4V957|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vitiosangium sp. (strain GDMCC 1.1324)|TrEMBL
MKIRNRLNPSNPCFSFEFFPPKTEEGTANLLKTLEDLAPLEPGFVSVTYGAGGSTRDKTL
ELVTRIKRETGIEAMAHLTCVGHTRDELREVLRRLADAKLDNVLVLRGDPPQGQKTYEPV
AGGFRHASELVRFIRDEDFNFCLGGACYPEGHVETASRDDDLRHLKEKVDAGLDFLITQL
FFDNAFYFDFVERARRAGINIPIVPGIMPITNYEQVQRFTRLCGATVPMRLGLQLERVKD
QPEALVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRARTT
>A0A0Q5ZAI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. Leaf396|TrEMBL
MTDVTTPVTANGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLEPKFVSVTYGAGGST
RERTHSTIARILKETALLPAAHLTCVGAARGEIDEIVDRYHEVGVRHIVALRGDPVGGIG
TPYSSHPDGYQSSAELVAGIKKRHGDIEISVSAYPEKHPEARDFDADIDTLKAKVDAGAT
RAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWFAAK
FEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAKSAQ
KAA
>A0A1E3JJZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus depauperatus CBS 7855|TrEMBL
MKITEKLQKAEKEGRPFWSFEFFPPRTAQASWMGLQNLYDRIERMRNLGPEFIDITWGAG
GKNADLTNSLVQVCQATIGIETCMHLCCTEMPKENVEWALKQAKAHGCQNILALRGDPVA
GTTTWEPTPGGFMRAVDLVRYIHEHYPNDFCVAVAGFPQGHPETPDADEGREQEMQWLKE
KVDAGADFIFTQMFYDTTIFFDWVRRVRQAGIMVPIIPGIMPIQSWEKFDRWVQREKIIV
PPHFYEALDPVKGDDEKVRQVGTKLVGDMCRTILGSKEAGIKGLHIYTLNLEKGARMLLH
ELGFEGRREQIVPLPWRPSLTPGRRSESIRPIFWTNRPLSYISRTSEWDEFPNGRWGDSR
SPAFGDLDGYPVSIGINPIDAYKLWGHPTTETELFDLFTRFCRGDLLKLPWSSQPPSPET
MVITEQLAMMNELGYLTINSQPAVDGVRSEDKVHGWGPAGGYAYLEFFVSPELLSPLLKR
IERDPRITYFAVNKHGDLMTNTHSEGPNAVTWGVFAGKEIPTIVDAVSFIAWKDEAYELG
LQWANLYPAASPARDLLTRVMNSFYLVNIVANDFKDGLSIFEPFLLNQTPIGKVVEGMKS
VAVGVKDAMGGQ
>A0A415WLB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM18-44|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A3A5P4J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AF39-16AC|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEGLTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>W6Y679|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bipolaris zeicola 26-R-13|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDEALEQAQVLGIRNILALRGDAPRSEE
YRDEDTPPEQDSNKDFTWAVDLVTYIRKQYGDYFCIGVAAYPEGHSDQSHPEHQDPVADL
PYLVEKTKAGADFIMTQLFYDVEAYDKYEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHAKLPTDILARLDAVKSDDELVKQVGVQIMDEIVEHIKARPDTCRRGFHFYTLNL
EKAVSHILEDTKLIPSTLIDDDEVIVETTPAINLEPPPNGIMPHRRRSSAVNSGPRNRVI
VSHVSAARSSNPSYEATEEEAGIPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKNDISTLFRRHIEGDLEAIPWSEQGLSP
ETLTISKQLLALNAKGWWTVASQPAVNGIKSTDTVFGWGPKNGYVFQKPFVEFFIPASEF
AVLQPKLDAHDQITYFAGNAAGDFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIWREWQRIYPPRSASSTLLGELRRDYWLVNVIWGDFVNGEGLWEFLLE
>W0H1U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. WH 8109|TrEMBL
MERDLRTALQRAIEAGDKVLTAEVMPPRGADPSHMLAMAASLQGRVHAVNVTDGSRAVMR
MSSLASCKLLLEAGLEPVLQMACRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAGDQA
DARPVNEFESVKLLQQVDALNRGVDPVQGTLPNGATTLFAGCAADPQSRSWSGLQRRLQR
KQAAGARFVQTQMVMDPEALERFQRELAGPLDLPVLAGVFLLKSAKNARFINRVVPGACI
PDALIHRLECAENPAMEGVAIAAEQVKRYLGIVRGVHLMAIKAEERIPMILDRAGLSSLP
G
>C6X229|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium (strain 3519-10)|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGSGIEDLYRNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERKITRMRPGTLGICSAIQHKYDVDTVPHVLCGGFSQEETEYLLVDCMYLGIEN
VMALRGDAMKGQQYFEPTVGGHKNAMDLVRQMNDLGRGKYLHEDKTCDENNKFCIGVAGY
PEKHIEAPSMNYDLKWLKQKVDAGADYVVTQMFFDNTKFIEFVKEARAIGINVPIIPGIK
PVAAKSHLQMLPKVFKIDLPEALISEVEKAKDNAAVKQIGIEWTISQCRELLDFGVPVLH
FYSMGKSDNIKQIARELF
>K6E7X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neobacillus bataviensis LMG 21833|TrEMBL
MSFLEKLNNQILIADGAIGTLLYTYGVDSCSEELNLSQPEQIQNIHRAYIDAGADVIQTH
TYAANYLKLQRYGLEDSVKEINSAAVRNAKKAAQNNAYVLGTMGGNRGVKPNSISIDELK
RSFREQLYCLLLEGVDGLLLETFYDLEELETVLTIARKETKLPIIAQVSLQEPGILQNQL
PVNEALTRLESLGADVIGLNCRLGPHHMLLTLEQIELPKHAFLSAYPNASLPTYTDGKFH
YEGDAGYFRQSARAFRNEGVRLLGGCCGTTPAHIRAFAEELKNSVPITEKVVKLKPKKIV
VESSAVKREFAPLQEIVKERPSVIVELDPPRKLDTSKFFEGAKALKDAGIDSITLADNSL
ATVRISNESLGYLVKQELNLRPLIHIACRDRNIIGLQSHLMGLHTLGLNDVLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTAFSIAAAFNPNVRSVEKAVK
RLEKKIHFGADYFISQPVFSEEKLLEVYEHTKHLDAPIYIGLMPLISSKNAEFLHNEVPG
IKISDSIRERMAGLNDHPHQATREGIEITKSLIDAALDLFNGIYLITPFLRYELTAELAI
YAKERAIDLRGNSYAENIVY
>A0A7K5R3A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prunella himalayana|TrEMBL
MVNETQHTSSSSRSEGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDKWFS
LEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCG
LETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVKH
IRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQPETFLKFMK
DCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVEL
AVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGILT
INSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIV
NVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEE
ESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A3B3Z0S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poecilia mexicana|TrEMBL
MVNQVQQVDGSWQSCRGDSSGTSNSSAESSKESSRCSTPLLDADRSDRLREKMRKRMESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITSYLAKAKHLGLKNIMALRGDPVGDDWEDEEGGFNFAV
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEQDLQHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAVGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKIIEPIKDNDAAIRN
YGIHQAVDMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWVEDPRRPLPWAVSANPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKNEQSVFEVFTCYITAQPNRNGQKVLCLPWNDEPLAPETNFLKDELEKVNR
RGVLTINSQPNINGKPSGDPVVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGHNMTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWHVIDDMFELLDSTPEPLTDEAGS
Q
>A0A7Z2VIG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella sp. MFER-1|TrEMBL
MKPDLRTALTLKPLVGDGAMATYLYQLGLPVGVSFEEFNLLKPDVIADVHRRYAAAGANI
IETNTYSAQHNRLSKYGLEKKTEEINAAGVAIARKAVGQDAYVVGSIGAVRGGAGKNVRT
AIVKRDFEEQIGALLAADVDGLLLETFFDLEELSLALSIIRKKSDISVICQFAVEDPHRT
HDGILLPDAFRRLKSEGADVIGFNCRSGPNGILRALETIPRDIGVPLSVFPNAGIPDYVD
GKVVYSATPEYFASSAIKFADAGARLIGGCCGTTPEHIAAIAGALRGYSPQTPEQNAVQA
GTAQPEQTVEVNEVSPPQIVEPSIVDLVRERHTVIVELDPPRDLDITKFMAGAQALKDAK
ADALTMADNSLAVTRMSNMALAALLKERVGIRPLAHIACRDRNLIGTQTHMMGFDALGID
HVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVVGAAFN
PNVKHLDKAVQRLERKISSGADYIMTQPVYDPELIVRIAEMTKHLTIPIFLGIFPLASGR
NAEYLHNEVPGIQLSDSVRQRMSGLEGSAGRAEGVRIAEELLDVAMAHFNGIYLMTPFMA
YEMTVSLTEYVRSKSKSLNAGK
>A0A8H5MAH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gymnopus confluens|TrEMBL
MKVTQKIAQCEKENKTWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
ELTAEMVKTCQSLIGIETCMHLTCTNMPKEKVDIALREAKLSGCRNVLALRGDPPVGKSD
WEAVEGGFVHGLDLVRHIRREYGDYFDIAVAGFPQHQTLPPVELEFELKCLKDKIDAGVN
FIFTQMFYDVDIFIAWVKTVRAYGITVPIVPGIAPIQTWNGFQRATSLAKIVIPQSFLDV
LEPHKTDDEKVRELGTDLVAGMCEKILNANLGIHGLHFYTMNLEKGTKMLLEKLQLVPRL
ETVKPLPWRQSLTPTRRQETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGISIKQTASEALELWGEPTSFEDVASLFARFCKGTLKALPWSDQKPAVETHVIADQLT
RMNELGFLTINSQPAVNGARSDDKTFGWGPPNGYVYQKAYLEFFVQPALLSVLLSYIERD
ANITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGLQ
WSRVYDDDSSSASLISELMESCYLVNVVHNDFHDANALFRPFFLAGEEHKASKDRLNGGI
PNGSASRH
>D9TI05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldicellulosiruptor obsidiansis (strain ATCC BAA-2073 / strain OB47)|TrEMBL
MKKSFREFLKEQSTVIFDGAMGTELLNRGFSLDFPLEWANIANPELVKEIHTDYILAGAQ
CIETNTFGANECKLKIFGFENEVERINRSAVKIAKEVADDKVFVIGSVGPLGKPVGSGFE
IDTRRAREVYKRQLYFLLDEGVDAIIFETAASTHEVQIAIEALKELNDKIPYIIQFSFTK
ELSTIYGEDIYMVTEFLKVTDADVVGLNCGNGPQKTLEALKVFSQHLKGPFSVQPNAGYP
QLVQGRLIYSTSAKYFASFVPEYIKLGAKVVGGCCGTTPEHIKAIKEKVKEFLPSIEVEV
VERKEEQKTVLKDTPSELSQKLGKKFIFTVEISPPKGIELEKTKEGVKLLKDAGADTVNI
ADSPMARVRISPIALAHILKEELGMESILHFTCRDRNLISLQSELLGAAALGVKNVLALT
GDPPSIGDHPQAKPVFDVNSEGLVLILSRLNSGTDYMGNPIGKATNFTIGVALNLNADDL
EKEIEKLKHKIENGAHFIETQPIYKPETLERFLEKVNFSLPPILGGILPLRSSRHAEFLH
NEVPGITIPDKIRERMRSSKEPAKEGVEIACEIVEKIKHMVSGIYIMPPFEKYEMAVEII
KNFKH
>A0A6I2IR10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium RIT711|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASPDELRTIAQDYWNSGIRHIVALRGD
LPPGGGKPDMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNYKQAHKFATMTNVRVPHWMAQMFE
GLDNDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPLV
>A0A7S4H740|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. Tan611|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHGIIKGIKDRTGLDAAPHLTCIDASREQLSAIASDYWNNGIRHIVALRGD
LPPGSGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPIAAA
>A0A0F0HXG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix sp. ST-888|TrEMBL
MALGISSTRTDRAQTVHDLLAAGDRSFSFEFMPPRSEDAERRLWDAIRRLEPLSPNFVCM
TYGAGGSSRGRTVDMVGRIATETTLTPVAHLTAVDHSLAELRNIIGQYADEGVRNVLAVR
GDPPGDPQGEWVRHPQGVTYAYELVELIKSIGEFCVGVAAFPQMHPRSENWDDDIRHFVN
KIRAGADYAITQMFFEVEDYLRLRDRVAAAGCEVPIIPEIMPVTNIRQLERFPQLSGSAF
PADLVRRFQAVADDKEAVRAIGIEHATAMSEQLLAEGAPGLHFITLNHSTSTLDIYQNLG
LHQR
>A0A2I1DL25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus sp. SH|TrEMBL
MTHSIEFFPPKNTAGEERLRETIRVLKALKPEYASVTYGAGGSTRERTFATVAMIRQEYD
LEAVPHLSCIGSTEAGIREILEAYRDQGIQKIVALRGDLPEGMSNPGHFEYAADLVAFIH
QFGGFEIYVAGYPEIHPRAASAPDDLQHLTEKVRAGADSIITQYFYNPDAYWQLLEDLQK
RGVDVPVVVGVMPITNFEQITRFSAMCGAELPQYIRRRMEALGDDLQSQTQFGIELLSRQ
CEQLLSQGAPSLHFYTLNQHEATAAIWQNLGL
>A0A2S7ELW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas populi|TrEMBL
MYPDTPSLASTLTEAYSLEVSATDIPGLTAAAPRIRRGATISIPYLPNQDNDARLAAAQM
VRKLGFAPMPHLSARRIASLNELHAFVTRAVDEAGVERCLVIAGDSTSPIGPFSDSLSLI
ETGVFERSGIKTIGVGGHPEGHPIMRATERWDVLERKCRSIAERGMAPLIVTQFAFDADI
VLTWLKALRERGIEHPVRVGVPGPAGVAVLARYAARCGVGACASMLSKYGISIGKLFGSA
GPDRFVDRLATGLTEAHGDVSMHFFPFGGIAQSVAWVEQYRSRTAPSWAD
>A0A4V4RA47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus aeridis|TrEMBL
MYQRLTSTRLSASAPLDRLDEDVNPSAAAPRRSTRTALSFELIPPRHDADTALLDNLIAG
LAEYNPDYVSVTSSRRSDWLEGTAALIKRIAETTDLKPIAHLACTAGTRDELTEWIRTLI
DAGVRGFLALRGDLPEGETSLPEGYLPYATDLLNLIQEVQDEQAFRLAAGKLALSVACYP
SGHAESKNADMDLDVLLAKQRLGADFAITQLFFEAQDYLDFVERSRLAGVRIPLIPGIMP
MTSLRRVERMGVLSGITVPQRVTDRLAKASTPDEEYEIGMAMSAELTREILDAGTGGLHI
YTHNNLAVTRDLLSRINL
>A0A2A3BE16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3866|TrEMBL
MEKAAIRPSSIDASIEMAPSQVIDSPDLPGLFPSGVRVYITDIGLADTPTLVKAARRVAD
LGYTAVPHMAARRLTTRQALETRVKALAEEAGVRDLLIIGGDVATPAGSFSSSFEVLETG
FVDKYGIAEVGVAGHPEGSRDFGDEAAIAALRMKSAWAERTGAKMRVVTQFGFDADKFIA
WADGLAVSGVDLPIHLGVAGPAKITTLLKYAALCGVGNSLNFLKKRSASLAALATSHSPE
SFVGPIEHHLRAKPESAIAQLHVFPFGGIKNTARWLYERGSWQDLEADDRSSIA
>A0A235ID56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. 'Peltigera membranacea cyanobiont' 210A|TrEMBL
MHHTHSPTAFNDFRRAVQAGEFLVTAEVAPPKGGDPAHMIQMAATLKGRVHAVNVTDGSR
AVLRMSSLMASVILSQNGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPDAKAVFDLEAVRLLQLIRKMNQGVDCNEKPLTDGALDLFVGAAVDPQCKSWSGLQS
RFERKIEAGAQFFQSQLITDFERLEKFMDSIAAGYKKPILAGIFLLKSAKNAQFINRCVP
GVDIPQHIIDRLAKAKDPFEEGIKIAAEQVQIARQLCQGVHMMAVKREDAIAPILDLAGI
APVNQLVSM
>A0A3M2RP22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium kuroshium|TrEMBL
MDRITDRIAALPADGSYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRREE
YRDPDDSEDDGGQDFNWAADLVKYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVEAGADFIMTQLFFDIKAYEHFENTLRDHPSGAFKTLPIIPGLMPIQSYQMIKRT
TKLSHAQIPEDILTRLNAVKGDDEKVKMVGVDIVSELVEKVKDIKSKTPGPKGFHFYTLN
LEKAVSFILERTNLIPEPPEDEEALVVDDAIPIPALQVNGSSNLRSGSHSRSRASRRHSS
VGSDPHNRVIVGDRPATHPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDF
PNGRFGDARSPAYGEIDGYGVSLHMSITQAVKFWGHPKTRQDINDLFVKHIQGELSAIPW
SEEELLAESSTIQPHLLRLNQKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEF
FIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVSSDKGGHVDGSSEAGPSTNAVTWGV
FPGKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSDSEKLLSGIKDEYWLVNLIHH
DFVEKDALWQVLSS
>A0A1E5L8J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuribacillus stibiiarsenatis|TrEMBL
MFICDKLKEKKPLISFEIFPPKKEFPIDTIYQTIDDLVNINPDFISVTYGAGGSTKDNTV
DIASYITEKYNLSALAHLTCLTSTKEDIENTLGALKEKGVKNILALRGDYPQNASPEDFQ
NPKYYKSSIDLIEHIKQYGDFCVGGACYPEKHPEAKSEEDDLLFLKRKVEAGADFLITQL
FFDNEIFYRFMEQTQKYNINVPVLAGILPVLNKNQVEKIVSLTGCKMPEKFLRILSKYEH
SPESLAEAGLAYAKEQMIDLLSWGIDGIHLYTMNKPAPTKEIISGLTTIRGFLNTKA
>A0A4Z0A070|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hericium alpestre|TrEMBL
MKISKKIEQAAKEDKVWWSFEYFPPRTAQGLQNLLDRIERMRQLGPEFIDITWNAGGRTS
DLTSELVKTCQGLIGIETCMHLTCTNMPKEKVDIALRASHVVSTTFQGISRFEQEAKQYG
CRNILALRGDPPMGKDEWEAVEGGFVHGIDLVRHIRAEYGDYFDIAVPGFPQMQLLPPEE
RAQEMKYLKEKIDVGVNFIFTQMFYDVDVFIAWVKTVREAGITIPIVPGIMPIQTWNGFQ
RATSLAKTKIPQSFLDALELHKNNDEKVREIGTKLVADMCRRILSADIGIRGLHFYTMNL
ERGTKMLLEELNLVPRVETIKPLPWRQSLTPARRSETTRPIFWANRTKSYLSRTENWDEY
PNGRFGDSRSPAYGDLDGYGVWIKQTKEDAIRLWNRPATLDDIKTLFKRFCKGELAALPW
SDEGLLSETSVISDKLAQLNEYGFLTINSQPAVDGARSDDKFFGWGPSNGYVYQKAYLEF
FVAPELLDVLIRHIDKDSGMTGITYHIISPQGDLRTNASDGPNAVTWGVFPGKEIVQPTI
VEAISFMAWKDEAYELGRQWAKLYESDSPSRKLISDIMDRWLLVNVVHNDFKKPDAIFEP
FFKAGAEFAAAQANGHAVHVNGNGHAN
>A0A3B8MQV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacteriaceae bacterium|TrEMBL
MTFIRDNTSAAPLAHITCVGSTRGDARALLSSFLAEGVRHFLALRGDLPEGTSEHQGELA
HATDLIELMRDMEHIPSQPEQIAVAAFPNGHPESASLEEDIATLLRKQDAGATLAITQLF
FYSSEYERFVEKCQSAGVSIPILPGIMPITSMGRLERVLELTGEARPHDLALQLSNAQDR
SEQEKIGIDWSASMVQELVEM
>F8AQK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum KACC 91563|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNTEPLFRGTQG
>A0A2V2E4B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriia bacterium|TrEMBL
MTTVKQLFNESRAASRPTLSFEIFPPKGDLDHRTAREVAGGLAPLGPDFISVTYSAGGGG
NKHSTNDVAEIIQSDFDTVCVAHLTCAGATASSIAASIEDLRAHNIENVLALRGDIPAGV
EPAEFRFAKDLIPTLADAGFCVGAAAYPEGHIDCIDPKVNIEHLKEKVDAGASFLVTQLF
FDNDYFYRFRERCTSARIYAPTTCGIMPFLSKQQIQRMVFMCGASLPSPIIKLLARYEDD
PASLRAAGIEYACKQLIDLEEHGADGLHVYTMNHPDIARACTEAIRCAG
>A0A4Q0YCS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halarcobacter ebronensis|TrEMBL
MLTDKIREKQKGILLYGITPPKINHSDEEIKEIAKKHIERISNLDVDGLVLYDIQDESDR
TDEKRPFPFIKTLDPCRYSHDYLQELKIPRIVYRAVGNYTTQTFKKWLEFTKQNQVHSVF
VGAASHEQKNPLTLKDAYALKREVNNNLCLGGITIPERHTKKGDEHLRIFSKIDESCEYF
ITQCIYDLEAAKIFLTDYAKYAKEHSYEMVPIILTLTPCGSTKTLEFMKWLGINIPNYLE
EELKESGNILQDSVKLSKDIFKELYQFGTKKGIPIGCNIESVAIRKAEIEASVELLNEIK
EIMKEN
>A0A1G5CX32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium XPB1003|TrEMBL
MKISEIYKDGHPTLSFEVFPPKTSEVYDSVVKATNEVAALKPDFMSVTYGAAGSTRTYTT
AIASNIEKSGVTALAHLTCVNASEESLKEQLESLSENGIHNILALRGDLPAGVESTSDWV
FKHASELIPIIKKYGDFCVGCACYPEKHPESKDIKEDIEGIRKKVDAGCEFLTTQMFFDN
ALFYNYMYRLREAGITVPVTAGIMPVTRAKQMERIISLSQAFIPRRYVAILDRYGDKPEA
LKQAAIAYATDQIIDLLANGIEHIHIYTMNKADVAQKIQENLSDIIPSCKKS
>A0A2T3G922|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium callitrichos|TrEMBL
MHKPMFSLEVFPPKRDAPVGTIYDTLDGLQGLDPDFISVTYGHGTHADRTATARIANTIR
NEYRIPTVAHLTALYSDEAKIDEALEMFEHAGVFAVLALRGDYIDGEEPVGVFEHASDLV
RYIRARKPDLKVFGACYPEGHIQSESIDADIEHLKEKVDAGATHLISQLFYDNEDFYRFL
DKARAAGIDVPIEAGIMPINGAKSLRSMAAKNRTRIPRDVESLLERWGSDVPTLREAGIN
YASAQITDLVAHGIDGVHLYTMNRPATTRRIWRNVRPLFQTAE
>A0A3E2NQC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter terrenus|TrEMBL
MKITEHIASANGKTLFSFELIPPLKGESIQGIYNAIDPLMEFNPPFIDVTSLREDYIYKQ
HDNGLLEKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLQFLGIEN
VLVLRGDARKGDASFVPTPNGHCYATDLLQQVVNMNNGVYLHEHHEGIMKSNFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGANFIVTQMFFDNQRYFDFVNGCRDNGINVPIIPGLK
PITSSKQLVTLSKTFHIDIPEGLSDAIQDAKSEKDVKDIGIEWMIDQCKELVKFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A1I1VYN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma endophyticum|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPIKGDNLKNLLDNIEPLMEFNPPFIDVTYHREEYIER
PMPDGTIQKIVTRKRPGTVGICSAIMHRFGVDAVPHVLCGGFTREETEDFLIDLHYLGID
NALVLRGDPAKPFSTFKAKENGYNYASELVEQVANMNRGIYLHEEDTALAPSNFCIGVAA
YPEKHFEAIDHDSDFKYLKQKIDKGAEYIVTQMFFDNSKYLDFVDRCRHEGITVPIIPGL
KPLSTRKQLQILPKLFHLQIPDDLVRAVEACENDQQARQVGVEWCIQQGHELTAAGAPVL
HFYTMGKADNIMKVARELF
>A0A4Q7AYZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bouvetii|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGDHFKIEVAAYPEMHPQADSFDLDIKRFCDKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTDSIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A7V9H081|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MRSAGLRAALTAARYEVLPTASIEAAVLESVPLGTTLTVTASAGKGLDATLDCAERLASH
GYQVVPHVAARMVRDREHLADLAARLVGFGVSNVFVPAGDADPPAGDYHGSLELIRDLTE
LGRPFAQVGITGYPESHPSISDDLAIQAMWDKRAHATYVVGNLCFDPVELRTWVRRMRAR
GINLPVLMGVPGPVERTKLLAMATKIGVGESTRFLAKNASIFARIAAPGGFSPERLLSRT
ADLFNDPVTGVAGLHLFTFNQVAETERWRQRLLGPVPVR
>A0A382T1K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MSIPETNNQAYTYRPGELLPELEGHISRGRFERVLRNGDFAVTAELAPPDSTDRNEVFEQ
AALFDGFVDAINATDGSGANCHMSSVVVCALLSYIGYSPIMQISCRDKNRIAIQGDLLGA
GALSICNVLALTGDDVSVGDHPEAKRVFDLDSISLITLIKKIRDEGSFLSGRTITNPPQM
FVGTSINPFV
>A0A806FP02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium animalis subsp. lactis CNCM I-2494|TrEMBL
MPWRHIRPLWHTYCVSHQNARITQHETQQMHTPMFSLEVFPPKRTSPVGTIYDTLDGLND
MKPDFISVTYGTGKSADRTATARIAHTIHSEYGIDAVAHLTAQYLTARDVDEALAMFDEA
KVSGVLALRGDRNSEREPAGVFTHASDLVCYIRERRPNLKIYGACYPEKHPQAATLDEDV
ANLKAKVDAGASHLISQLFYDDDDFIAFLGKARAAGIDVPIEAGIMPVTNAKSVRRMTNM
CSSRVPRKLERMLEKWGDDPRTLREAGIIYASEQISDLVAQGVDGVHLYTMNHPSVSRRI
WQNVGNLFEKA
>A0A382PLL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
KPSDGRIKRDNGGFSRKIIDGEFAVSVEILPARGTAPKLLQRKIDFVGGLAASGLADGLD
ITDGSRGIPLMPPGDFIHVVRERLGWQPGQDGLELMPHFTSRDLNTMGLQARLVGYWANG
IHNVILVTGDPPKMAPSYPPSTAVFDLTSVDLIRLVNNGLNAGVDFGGQALGKHADPGTR
FTIGTGFEPESLDLTAEMEKLTRKIEAGADYIMTQPAFAWEPLEVLSEVRQSVPVLVGVL
VLTSLDHALRMRQVPGVVVPEAVLNRFGQSDDRASQAQVGRDLAAEQIRRIQSEEWAGVY
LMSPASHDPVIDVLRAGLT
>A0A383BW60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MQLTVRDRNRLALQGDLVGSSALGVHNILCLSGDDPKNGDQPKTTVVNDIDSLTLIETAD
MMRRKKQFPSGRIIEPAPKLCIGGAEIPTEGKPDPEKILIKINMGVNFFQTQYVFDEFIL
KEYMKVLEDAGILEKTFFIIGLGPFASAKSAKWMDKNLFGVDVPEQIIKRLEQAQDAKKE
SMNICQELISKFKDIKGVKGIHLMGHNKEEEIAKIIQEARKS
>A0A1V9BCL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. 46C-IIa|TrEMBL
MGLLDDLKQRVLIADGAMGTLLYSHGVDRCFEELNLSKPEEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSAVPLDEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLTIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPTRAVLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIEAMARALHDRTPVTKKTVKQRAVSVS
VQSDIPLAATPLPELARARRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLA
TPRISNVAVGSIVKERLGVRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLISQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVER
MEKKIQCGAHYFLTQPIYSEEKIVDVHEATKQLDAPIYIGIMPLVSARNAEFLHHEVPGI
TLSDEIRARMAACGNDPVQAAREGIAIAKALIDAAFDLFHGIYLITPFLRYDMTVELVRY
IHEKEAAAKERKVVHG
>A0A382X867|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKISEKLKEYKNQGKTFYSFEFFPPKSDFGLDNLYSRIDRMASLRPAYIDITWGAGGSTS
DRTLKMSKIIQKYFGLDVMMHLTCTNMPKDSIRQVLIDAQKNNISNILALRGDPPEGSAI
WEKDDQGFSYGIDLVRYIRKEFGDNFFIGVGGYPESHQEQNDIDLDISFLKKKVDAGSDI
IITQLFYDVENFLIFRDKCSDVGIDVPIIPGIMPINNYARFNKFTQFCKVTIPKSVTRAL
EPIKNDDSSVIDYGIE
>A0A1A5RJQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3873|TrEMBL
MSIRHQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQIF
LGAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>A0A058Z2L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fonticula alba|TrEMBL
MPPSSVECEGLPQGGPPRGRGDQGKINLLNRFERMKALGPSFIDITWGAGGSTSATTLEL
TLAAQKEIGLNTCMHLTCTNMDREQIDHALETCHANGVQNILALRGDPPQGQERWVATDC
NFSYGSDLVKYIRQKYGDHFCIAVAGYPEGHQDNECKESDLQHLKSKVDAGADFIVTQLF
YDVEEYLRFVARCRAIGITCPILPGIMPIYTHAGWTRMTTMCKVAVPPAMAARMEELKDS
PEEVLAYGEDFIVQMMTQLQEAGVKQFHIYTLNQDALVTRILRRLDLLQEESPKSASLPS
TAPTSPSNSP
>A0A6J4HYR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Chthoniobacterales bacterium|TrEMBL
MAPGDRVGRSRCLDPAVLTFRTRDVKPTAVGLLDELQERIVCGDGAMGTLLLDAGVPVDR
CLEELCVSEPDRVRMVHEQYVAAGARLIETNTFGANAPRLERFGLQARVAEINSAAARVA
LAAARGKDVCVAGSVGPLGISESDATERGIDRAACFREQITALLDGGVQILFFETFMSFE
EMQIALGARPASDAIVVALFACEPEGRLQSGMPVVDAFAHCRQLGAHIVGANCMNGPHAM
VQLLQKIPAGDLLAAYANAGYPRYTEGRYVYPTAPDYFGITGREMAEQGAGLIGGCCGTT
PAHIAALSRAVAEMKPVRSKQVRAISQAPLETFHTQRRAEDSLVEKLAQGQRVIICELDP
PKSLALDKFFAGAQALTRAGCDAITLADNSLAILRMSNLAVGAMLKERFGITPLLHISCR
DRNVLGLQSELLGMAALGMRHVLPLTGDPARVGDHPGAKSVYDVNSIELMAIVKQLNEGF
THSGKPLKAKTEFVIGCTFNPNAKNLDAQVQRLERKVAAGAQYAMTQPVFDAELIAETKR
RTAHLGIPLFIGIWPLLSGRQAEFLHNEVPGILVSDRVRAAMAGSEGAEGRARGLKLAKE
MTEAALAEYAGVYLITPFLQYETTVELAEFARAL
>A0A382CAZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MNISYEFFPARTEQGKHNLLTTLSELDTTNPDFYSVTFGALGSGQDATIDTISEISSATD
VSVAPHLTCVGSDIHQMTKLLDTYVNLGVTRVVVLRGDIPPAIRDIGDFHYANELVEFIK
EQYNDHFTIHVAAYPEKHPQSKNVISDIEYFVNKIKAGADGAITQYFYNTDAYFRFVDEV
QRLGVDVPIVPGIMPITNYDQFVLFSRNCEAEIPSWILSRLKHYRKDMDSLQKFGQDVVS
EMCLKLKSGGVEDFHFYSMNRIEPVLSLAKNISQAGDKLLTEDFKVKVLN
>A0A381ZXJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MTKVIDRYVESTNQIVVLCDCTPPRSGDPEALDRVAVVEADYICVAYNPGKIPRANSVTT
AHIIRERTGRDVVFNVATRDMNKLAIQSQLLGAQMMKLQNVVALQGDGFTDAETKQVKLV
DDFTSTGLIEALSEMNNGLDYRGSKMRGTTDFCIGATLDLERDLVREVKLAQRKIKAGVH
FFITQPIYDLNLRQRFLDEYEIQAGNPFATPVFWGLQVLDKDGIALGNVPPQMRHQLDSG
KS
>A0A7L6XQD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. RHB21-C05|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A381WSJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MHLIELYKKQNFVFSIEIFPPKTEKGMDKLKMTLEKFNGYTPDYFSVTYGAGGTSRANTH
EMAAHIRHDLGVPVMAHLTCVSHSAKEIDDVLTKLKNSNIENLMALRGDPTLGTEHFILP
EGGYHNAGELISAVRKHSDFGIGAAGYPEGHVDNPDKDDDRKHLHGKIAAGAEFIVTQFF
LDNTYFLRWRDKLREEGANVPLVAGILPPSNWKATKRMSEMCGVSIPQDLAEALLKHEND
PVASKEIGFVHVEKQIEGLLREGVEGVHLYALNNLDTVKRLGPKLREAAGTSPACSAD
>A0A382JJN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MNFSLEIGPHTDLKTLPTLKDVYITFLPGGDYKETASKADELFKKGFNPIPHFSARSIQN
ETQLKEYVSRCKDVGVKQALVIGGSIDPVGDFDSSIQLLETGYFEKMKIGIAGHPEGSPD
ISDSKLEKAMIDKKPYADYIVTQWLLDHKLIIDFISKQTIPVHVGITGPLKITSLIKFAN
IVGAKNSLNFLKSNFSKALDLMKPRDPNDLIGKVKSHSDYFHIYTFGGLKETNKWLMENK
YV
>A0A381UK03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MVPITAITELIAQPRSRPFIVLDFSPPRGGIPHLLSHASSLTPDLFSIAYNPGKSVRANP
IMVAHWIQNNTGIPAVFTLATRDMNKGALQGILLGAQLLGLNNVVSVMGDELSSSEQLSQ
KTISDFTASGFVNSIKRMNIRVDFRDRFLRHPTGFCVGATIDL
>A0A381WZA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MANRFVVTSELVPPKGTNLDTLLQTARSLEKYVDAFNVTDSHAAHMSLSPIAAAHTLITE
GFEPILQMVTRDRNRIAIQSDMLGASLLGITNLVCMGGDPPNVGDHPHAKPVFDLSTAEL
IHAAFTLNSGNDEVGHKLSQSTDFHIGAVVNPGSSDLGTEIKRMEEKVEAGATFFQTQAI
YDVRSFVDFINSIEHLNVTIIAGVMPIKSVKMAEYANNNIPGIHIPDWMIQRIANADDIK
ETSVQLAAELISELAPFCGGVHLMALGAEDRIPLILDRARR
>A0A381RXI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MHLIDLYQKKDFVFSIEIFPPKTEKGVEKLKTTLEKFKSCTPDYFSVTYGAGGTSRANTH
EMAAHIHHELDVPAMAHLTCVAHTEKEIDEVLTKLKNSEITNVMTLRGDPTAGTKHFVQP
KGGYHYASELIAAVRKHSDFGIGAAGYPEGHVENPDKDDDRKRLHEKIAAGAEFIVTQFF
LDNTHFLHWRDQLHKEGVSVPLVAGILPPANWNAISRLSDMCGVSIPEKLAQALIKHESD
PEVSKIIGFEHVEKQIEELLQEGVEGLHLYALNSLETVDRLGPKLKEASGT
>A0A381PF36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKFKDSIYDTFSFSADLNLGAVGSVEDLLGQARILSGSVDGIHVSDGPNDGVHFPALAAA
RLLIENDIDPILQISCRDKTRSTLEIEIAGALALGVTSMLLVRGESAGISGTSDRIVKVS
TTELIQLVRSLEDRAEQANLSVGTIATVFKPAADWRPQALLKKTHAGANFIRTQLCFDTD
KLNVYMPNLVRSKVTWKAPIFVNLAVLPSAKAAKWLAENLRGSLIPQKVIKRMEQAVDPI
SEGVDVAAELIAEFNTIPGISGVCLMTPGPPELILEAIKASGVRQE
>A0A523YJE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium|TrEMBL
MIITQQKPFEEIIGFLERSNAVFICGCSECATLCKTGGEEEVKQMKKRLEETGKKGSGWV
VLDPACNILENKKHFRENKAQLSKADSILVLACGNGIQAVSESIDKIVYPGVNTLFLGDI
IRFGQFEERCQFCGECLLDKTGGICPISRCSKSLLNGPCGGSENGKCEIDPDIDCAWQLI
IDRLSKQEQIDRLKEIIPAKDWSTSRDGGPRKLNIREPHHKKVATSKEKKTEEAKTPVSS
VKANSNLRRILDGGEFAVTGELGPPKGADAEIIKKKALYFKDSVDAVNITDNQTAIVRMS
SIAAGVILSQMDIEPVVQMVCRDRNRLAIQSDILGAAALGIRNVLCLSGDHQKFGNHPQA
KNVYDLDVIGLIQVLKSMRDEKKFLSGDSLTVSPQLYIGAVENPYADPYEFRAIRLAKKI
EAGCDFIQTQGVFNVKKFRDWMKIVRDSGLDGKVHILAGVIPIKSAGMARYMRDYVSGVS
LPDEIVSRMEDAKDPKEEGTRICVEIIEQLKEIEGIHGIHIMAVAWENIIPVMVKQAKLW
PRPGLKNIRAS
>A0A382L569|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MSKLKDSLEAGTFTYTAELIPPKGTNLESMFEKAEILNGLVTAFNLTDSYTAKMSMSPLA
AARLLLDRGIESILQFTCRDRNRIALQGDLLGASALGLSNIMCMGGDPPTIGDHPEAKPV
FDFDAVSLLGAITTLSQGHDIHDNPLRGTPQFFTGAVTNPGADDLEWEINRLGQKIDAGA
QFFQTQAVYESVAYEKFANATAKYNVPFLPSIILLKSGDMARMFNEKVPGITVPDDIVKE
MDDAATPEEKSTKSIEIAARTIRELRPLCQGVHLIAAGWESKLPQVIKLATS
>A0A381NG11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MIEDGLVHIFDGAMGSVLYTRGVFVNICFDELNLSNPEIVRRIHQEYVSAGSEILETNTF
GANPVKLSSHSLGDRTEEINEKAAHLARDAGAGRVAVVGAIGPLGIRIEPWGPTARAEAT
AFFERQVNGLLAGGVDGFILETFADLNEIDCAFTAIRKLGDLPVIAQMTLGQNGKTVYGH
TASQIAQELTSIGVDVIGLNCSVGPAVMLDAIEDMADTTSVPLSAQPNAGLPRTVRDRKI
YMATPEYMAQYARRMVDAGVRFVGGCCGTTPDHIKQIRDSVRSGQPRPVMVRVTDVDQEG
SEILDPVPLEACSAWGRKLSRGEPVVSIEVLPPRGWDRNAIVEPAHELKDAGVDSLAIVD
GPRSRSRMGALSAAVIVEQEVGIEAIVHYTCRDRNMLGMISDLLGAAAAGIRNLLVVSGD
PSVHGPYPDMTEVFDIDSIGLTNVVTGLNQGIDPAGNSIGDPTKFVQGVVANPGALDLER
EVTRFRYKVEAGASFVVTQPIFDPESLERFLDKIHQWKIPVVAGIWPFLNLRNAEFLANE
VPGATVPEKIVDRMRRAQISGDEEALNEGVEIAAEMIDAVRPLVQGFHLSAPSRRVDVAL
RVLDEAGVSTNT
>A0A4Q2Y9S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MHIRDILAASKPSLSFEFFPPRTSASWEELYQTIRELEPLNPSFVSVTYGAGGTTREMTH
DLVVRIKQTTSIPPIPHLTCVGHSEAEVEAILTRYAAAGVSNILALRGDPPRDRPDYDWS
EGDFRHAADLVSFIKRFNEKGIHPDPRGFGIGVAGFPEGHPSTPNRVDELDHLKAKVDAG
ADYICTQLFFDNHDFLDFRDRCRFTGIGVPILAGIMPISSLQGMKRMAELAAGARYPAKL
LRALDRAGGNPQSVERVGIHYAAQQCAHLLDQGVEGIHFYTLNKSRATREIYANLGLTSV
DAG
>A0A4Q8BGW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora kangleipakensis|TrEMBL
MALGLPSVLPNPQPAIGELIRAGQPTFSFEFFPPKTEQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVPHPQGVQYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFQRVADDPDAVRRLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWQHLQ
AGTRV
>A0A1N6PBP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. RU37D|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYRNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTKGGHGSAMDLVHQINDLGRGKYLHNQDKECDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLRQKVDAGADYIVTQMFFDNRKYIEFVKKAREMGITVPIIPGI
KPIATKNHLKILPQIFKIDLPEELIIEVEKAKNNETVKQIGIDWSINQCKELLDFGVPVL
HFYSMGKSDNIKEIARELF
>A0A150X4U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivirga spongicola|TrEMBL
MKVTEHIKNAEGKTLFSFEILPPVKGESVQSIFDAIDPLMEFKPPFIDVTYHREEYMYKK
RENGLLEKVTTRKRPGTVGICAAILNKYGIDPVPHIICGGFNKEETENALIDLDFLGVEN
ILVLRGDAIKSEGRFEPDPDGHSYATELMDQVNELNQGIYLHEEVTRNPTNFSIGVAGYP
EKHFEAPSLKSDMKYLKQKVEKGADYIVTQMFFDNKKYFDFVDKCRSNGIDVPIIPGLKP
ITTLKHMNILPSIFHVDLPDDLVDALDKCKDNAGAREVGIEWAIQQSKELMEAGVPVLHY
YTMSKSQVVRRIAEALF
>A0A482SNP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon|TrEMBL
MKIVDKIKNNATEPYFSFEFFPPKTEAGVENLYLRMDRMTALQPIFVDVTWGAGGCTKEL
TMAICEYTQTYFGVDVLMHLTCTQLSIDKLKRILAAAKEAGIQNVLALRGDPPKGSLAWE
PVSGGCEHAIDLVKLIRKEYGDFFCIGVAGFPEGHPHSKETNITQDILHLKEKVDAGADF
VLTQFFYDPQIFLAYRDQCVSVGINVPIIPGKITYM
>A0A0F2RW38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium BRH_c57|TrEMBL
MTATTPPRPVDVSFEFFPPKTEKMQESLLAAVRRLAPLAPSFMSVTYGAGGTTRERTHDT
VTQIQREAGIPAAAHLTCVAATREEVDAVAKSYWDAGIRHIVALRGDPPEGESTYVPHPG
GYAFAVDLVKGLKAVAPFEISVAAYPEGHPQAQSLEADLDNLKRKIDAGATRAITQYFFE
ADTYRRFMDRVAKAGITVPVVPGILPVTNFATVVRFSEACGTTVPKWLHQRFEGLDDDPE
TRKLVAATTATELCEDLQRDGVTQFHFYTLNRADLTYAICHVLGLRPAVHPATV
>A0A7J2R1R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon|TrEMBL
MSPVISEKWYGGRIQVAEKKVYSKLGEKLAKGEFILTGELEPEKTCDLSHTIQEAKEMAP
YIVAANVTDSPLSIVTINSMAAAHVIQRQTGLECVWQLTVRDSNKIGLAGQIMGAGALGL
SNMLSLTGDHTALGDCPESKPVFDLDSATLIKLVREMVDKGSINGHEIETPPKLHVGAAA
NPNADPMEAEILKIGRKAEAGVEFLQTQVVYDIDMTIEFLRGIQKYNVPILLGIFPMKSY
GMAKGFDMFVPGVDVPKEILERWKSVKTNVTDKKEQKQTYDQLNYEFFKPFITELKTKGL
LAGVHCMAVHYTRIFPKLIEVIKG
>A0A7Z0RKW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium changzhiense|TrEMBL
MAMSQAIHLRDQSGVLDDFSVEVTTKDTAQLAAMSGAIPKGTIISIPFLSTESDADRIRA
AKMVRQAGYVPLPHVAARRLGSESMLSAMLSALVNDAQVSRLLLVAGDADPPKGPFLDTA
TILRSGILEQHGISNVSIAGHPEGHPVQNAAMLTSALLEKRLIMEAANIEWSIFTQFAFA
SDPVLAWIGELRRLGIEVPIHIGIPGPASVRTLLKFAAVCGVSASTSVLKKYGLSITQLL
SSAGPDALVNEYATGLSNAEYGDVRLHFYPFGGLHKTVDWLQEYRTRPS
>A0A0J0ZPC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii MRSN 3527|TrEMBL
MSHLSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKVKAGADFIITQLGYDIEAL
KQAKSFLTKHNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQVGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVT
TSKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A1E7G846|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. Ant1|TrEMBL
MHFNFREKLNSSKFLVTAEVSPPKGTNFSVPLEDARQLKGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDFPSCGDHPGAKP
VYDLDSVQLMQVVSKLNSGVDFAGNKLDGGTSFCTGAVSGINSEKPLQIIKLEKKTKCGA
DFIQTQAVYDVGMFEEFMEAISHLEVPVIAGLIPLKSFGMAEFMNKNISGISVPEEIMFR
MKEASNPVEEGLSIASETIKELMSFSRGVHIMPIGSHKNTPKLLSMTGISGK
>A0A2N8SGN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas kunmingensis|TrEMBL
MSQPRSHSFSFEFFPTKTDAGHEKLMATARRLAEYNPDFFSCTYGAGGSTRDRTLNTVLQ
LDGDVKVPTAPHLSCVGDSKQELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNYEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMESIQT
FGNQVITEMCEELLAGGAPGLHFYTLNQAEPSLAIYNNLGLTA
>A0A418NBR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda aequoris|TrEMBL
MKITDHIKKAKGETLFSFEIVPPVKGKSIQELYRNIDPLMEFKPPFIDVTTSREEYIYKE
KDGLLDKKLTRTRPGTLGICASLKHKYDVDTVPHVLCGGFTREETEYLLVDCQYLEIENV
MALRGDARKEEKYFIPTQGGHQYAAELVKQIHDINQGNYLHEVIEGHEMGDFCIGVAGYP
EKHMEAPSLQSDLKRLKEKVDLGADYVVTQMFFDNKKFFAFVEAAREMGIDVPIIPGIKP
IAVKQHLQLLPQVFRVDIPQDLIEAVEACKTNQDVRKVGVEWAIQQSKELKTAGVPVLHY
YSMGKSDNIKDIAKELF
>A0A0Q7WV93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. Root554|TrEMBL
MISPRAPQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLG
GAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRVMRDNGKFLSGRKLTTPPQ
LFLGAAINPFAPPYDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQRVRDLGYTEKVF
VLCGVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIIDEVKEIPG
VSGIHVMAYRQEEYVAEIVDESGVLKGRQPWKREARADDRMVADRLESILKDDITETQVD
MVKTAH
>A0A1H5CXI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coleopterorum|TrEMBL
MSHDRPLSFEFFPTKTDAGHEKLMGVARQLAAYKPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVNVPAAPHLSCVGDSKQDLRGLLDQYRSAGIKRIVALRGDLPSGMGMSSGELRHANDL
VEFIRAETGDHFHIEVAAYPEMHPQARNFEDDLVNFARKANAGASSAITQYFFNADSYFY
FVERVQKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLSS
>A0A5B9ENH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Octadecabacter sp. SW4|TrEMBL
MSTPAVSFEFFPPKNLEGSFRLWDCVNTLAPLDPAFVSVTYGAGGATRKLTHDAVATIHK
TSGLNVAAHLTCVDASRAETLDIAQGYADIGVTQIIALRGDAPKGSDGYHPHADGFHGSI
DLIQALAQTSKFAIHVGAYPEKHPESASQQADIDHLKRKFDAGATSAITQFFFEADTFFR
FRDACVAAGITAPIIPGVLPVENWNGARKFAQTCGTSIPPLIADAFENATRDGTTDLLAT
ALATELCDDLIIGGVDHLHFYTLNRPELTRDVCHALGITPKVQLQNVA
>A0A2V3DQA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter psychrochitiniphilus|TrEMBL
MSPPSLIQVSAPASQSAPIALSYELFPPKNAAAEATLWQTIRELESTNPDYVSVTYGANG
SNRNTAVELLNRLLTETSLRPLAHLTCVGNTADELAEIISELLDHGVRGILALRGDLPQD
GPAEPRAGSLAYAQDLIELIRRVEQRRSALLCAGKVAIGVAAYPARHPESPSIEHDVEVL
LAKQRSGADFAITQVFFHADQYRDLVSRARRAGVSIPIIPGVMPLTSLRRVQRLGDLTGV
EPCPKLLDSLGRADDAAQSRRVGVKATVDLARAALDAGAPGIHLYTFNEHAAALEVLNKL
ELLRPGRPQLGSRSAASALA
>A0A239J246|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerovirgula multivorans|TrEMBL
MSLLMEVLERGEFAVTAEMAPPKGIDLHHLMECARAIKGRVHGVNVTDFQSAVMRATSLV
TCKLLKDEGLEPVLQMTGRDRNRIAIQGEFLAAGVFGIQNALALTGDHTVVGDHPKAKPV
YDLDSVGILQAATTLMSGKDMSGNDLQGTPEFFLGACVTPRFDPVEAQILKMEKKIKAGA
KFFQTQAVFDLDTMREFREKTKHLDAKVLAGIIPLKSAAMAKFMNNNVPGIFVPDELIER
MKNTEKDLRVQEGIKIAGEFIKQLREENLCDGVHIMAIGAEENVPAILDAAEL
>A0A1I3R0C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas kunmingensis|TrEMBL
MTASNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDTKAELRELLNLYKEAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRELGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQA
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>C4Y9Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clavispora lusitaniae (strain ATCC 42720)|TrEMBL
MSVVERIQALGPDEKFCSFEFFPPKTDAGFRNLLARLHRMRDLNPLFVSVTWGAGGSTSE
KSLELAVTCQQLLGISTVLHLTCTNTNKAIIDDALSRAKAAGIRNILALRGDPPRTREYW
TPECSFRTAVDLVRYIRAQYGDYFCIGVAGYPEGHVDGSDGAEQDPKRDLPYLEEKVAAG
ASFVVTQMFFDADKYVAFEKMVRASPVLKDVVLIPGLMPITTYKVFTRATKLSHASVPAA
VAEQLSSAAVDDDQVKKIGVDVLSQLVADVSARSAARGFHFYTLNLERAVAAIVESCPEL
RGSAARLSRSRASSDPFESDSETSAPNAGKVESVPDSVPLVRDRRVTLAATWDDFPNGRF
GDASSPAYGEIDGYGPSLKLEPPEAVAVWGTPQSVADVSRVFIDYLSAKISSLPWVSTEL
SPETALIQEQLFELNSRGLFTLASQPAVDSCPSSDSILGWGPRNGRIFQKSFVEFFVPKT
EWERLLRLMDKDISDKTITYFCGNSKGEITTNMPHKSSQRTAITWGVFPSKEVLQPTVID
RQSFQAWNEEAFGLWLDWARCYAPDSPSYRLLAGIHSDYYLVSIVHNNYLAENALWDTLL
Q
>A0A0E2DT11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira santarosai str. JET|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSRLDPDFVTVTYGAGGSTRSK
TAQILSEISKNYSFPTVSHFTCVGANQEQILKTLKEIRSSGIVNLMALRGDPPKGEGQFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPNAKNLEEDVENLKRKVDAGADFLVS
QLFFVNSIFENFLNLVRTAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A553K2D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus rhinocerotis|TrEMBL
MSTAPHDPRTVAQLLAAADSPLLSYEFFPPRRSEEEQKFWTTVEKLEQLEPDFMSVTYGA
SGSTRDRTIEATRLLAARGTLTVGHLTCVSQSREDTARTLGAFEDAGVHNILAIRGDMPG
GPHVPWEQHPEGIATATEMVEFIKSRGEFCVGVAAFPNVHQPDNDPELDARIVVEKAAAG
ADYAITQLFFEGHRYVELVDRVRSRGCDIPIIPGIAPLTVITQVERFAQLADCELPADFV
AQLNAAGDPAEVRRIGIQRAVDVCLEVLEAGAPGLQFFTQNRWMATTEVIARLPGYRAR
>A0A6S6NFK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium vitis|TrEMBL
MAHTSSKRDQARPFKLSFEFFPPKSEEMEAQLWATVDELTGWAPEFVSVTYGAGGTTKAP
TLAAVRRLLAETPLATASHLTCVGATREEISQVVEDFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGFENAAALVKGLKELGDFEISVSAYPEKHPESADLAMDLDMLKRKVDNGATRALT
QFFFDNDIFERYLDKVRAAGISIPIVPGIMPILNLTQLKRFAGMCGTSVPTMLDQRFEGL
DDKPTERASVAAALAAEQIADLQGRGIDEFHIYTMNRAPLVNATLERLGLQRSDTAAADR
AGVVA
>A0A368YNK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium sp. DL-01|TrEMBL
MKIKDIFAEKKVVFSLEIFPPKYDMHIETIYKVLDKFKKIEPDYMSVTYGAGGGVNNNKT
CEISSLLKEKYGVEPLAHLTCINSTQENIDDILERLKANKIENILALRGDKPLDGSQTGN
YNYAYQLIDYIKKKGDFGVAAASYPEGHLETENLAEDIEYLKHKVDYGVDYLITQMFFDN
QIFYNFISQIRKKGIDIPIEAGIMPVINKKQVGRIIELSDAYFPEKFKKILVKYQDNPEA
LRDAGIAYAVEQIVDLISSDVDGIHLYTMNNPFVARKIKEAIESLLKHINHKKVG
>A0A6S6N4J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium vitis|TrEMBL
MAHTSSKRNQARPFKLSFEFFPPKSEEMEAQLWATVDELTGWAPEFVSVTYGAGGTTKAP
TLAAVRRLLAETPLATASHLTCVGATREEIAQVVEDFRAVGVKHFVALRGDPPTGVGSVY
QPHPGGFENAAALVKGLKELGDFEISVSAYPEKHPESADLAMDLDMLKRKVDNGATRALT
QFFFDNDIFERYLDKVRAAGINIPIVPGIMPILNLTQLKRFAGMCGTSVPAMLDQRFEGL
DDKPTERASVAAALAAEQIADLQGRGIDEFHIYTMNRAPLVNATLARLGLHRSDTAAADR
AGVVA
>A0A1U7WYR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nicotiana sylvestris|TrEMBL
MKVIDKINESAKTDRVVFSFEFFPPKTEDGVDNLFERMERMVSHNPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPATGIATQETYENDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPADITAALEPIKDNEEAVKAYGIHQATEMCKKILATGIKTLHLYTLNMEKSALAILMNL
GLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDEYPHGRWGNAQNP
SYGALSDYQFMRARSRDKKLQEEWAVALNSVEDIYERFMNYCLGKLRSCPWSELDGLQPE
TKIIDEHLGNINTKGFLTINSQPAVNGAKSDAPSIGWGGPGGYVYQKAYLEFFCSHEKLN
ALVEKCKAFPFLTYMAVNKEGNWISNANQTNVNAVTWGVFPGKEIVQPTVVDPASFMVWK
DEAFEIWSRGWAQLFQESDPSRKLLEQVQNSYFLVSLVDNDYINGDLFAIFKDI
>A0A831XHN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus islandicus|TrEMBL
MRIRDLLLARRGPLFSFEFFPPRTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRER
>A0A7X8J1C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacteria bacterium|TrEMBL
MDIKKYIEKNGYIIIDGAMGTYYSTLSNKETTMSENANIDDKSIIKKIHEEYIDAGAKLI
RTNTFKADIYSHKKDRDYTKLIIENGCNIAKDAVNNRDIYIGASIGPINANTETKSEDIY
NEYLFIVDTFISCGINIFIFETFSNYDILEKIAKYIKGKNPNSFILVQFMVMQNGYTGQG
VSIKNISNNISSNEDIDAFGFNCGTGPIHIYNNIKQCNFKDKIVSALPNAGFPDIVNRKI
VYNQNTDYFAKIMIDIKNIGIKILGGCCGTTPAHIKKLSEKIKNIGLENIEVKVKIEDKN
TFELDKNIKKRVLDIAVELDPPFGADISKIMSAAKELKESNINYITISDSPIGKVRVSSM
LTATKIQNETGIDVMPHICCRDRNIIGLKSDVLGAYVNGIKNMLVVTGDPIASADRNEIK
SVFNLNSVGLIKLIDKLNNEEFKEDKVNIAAALNLNVVNKKAEISKMEKKIEAGAKLFLT
QTIFEDSAIEYLINMKKEKGIKIYAGIMPLVSYRNALFLDNEIPGINIPDKYINMFSERM
NRDEAEEVGIEIATQIIYKFIDYIDGLYIVAPFNRVNMVKEILKKVNV
>A0A6L5HT81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas helleri|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKDDLRGLLTQYKGAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDISNFVRKANAGADSAITQYFFNADSYFR
FVERVRAAGVMIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDAKSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A259EZB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium 17-61-9|TrEMBL
MTERTFSFEFFPPKTAEGMDKLRATRDQLAQLKPKFFSVTFGAGGSTRDRTLETVREIQA
SGSEAAPHLSCIGSTEASIRDILSEYKSQGIRHLVALRGDQPSGTMDAGEFNYANELVSF
IRRETGDWFEIEVAAYPEVHPQARSHSEDLANFKRKVDAGADAAITQYFFNADAYFRFVD
DARALGVALPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLPSLRAFGLDV
VTDLCERLLAGGAPGLHFYTMNQAGPTTTIWQRLGL
>A0A5C7TG40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodobacter sp|TrEMBL
MTAPRISFEFFPPQTLDASFKLFETVQALAPMSPEFVSVTYGAGGTTRKLTHDAVGTIHR
NYGLNVAAHLTCVEATKTETLEIAEAYHAAGVRQIVALRGDAPNGADRFTPHKDGFASSV
ELVAALAARGKFEIAVGAYPEPHPDAADPTADVRWLKRKVDAGAAKAITQFFFDADTFFR
FRDDCVAAGIHVPIIPGILPIQSWAGAKRFAARCGTKVPAKLDEAFTTAARDGREDLLAL
AQCTALCDRLIAGGVEDLHFYTLNRPHLTREVVRALGITAQVQLEKVA
>A0A2L1HRN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SWI6|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDELRALLNQYQAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEHDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EDVISRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A5A8B4W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia chilikensis|TrEMBL
MRISEIYRSGTFGLSVEIFPPKSESGDAELFRTLEELVRYKPAFVSCTYGAGGSTSKRTI
ELCDTIQKDLHSTATAHFTCVGSTREQLVDWLKEASEAGIGNIMALRGDPPKGEETFIPA
DGGLKYASELVTLIRENFPEMGIGVAGYPEVHPEALTPQADLENLKRKVDAGADAIYTQL
FFNNQHFYRFQERCAQAGIDRPIIPGIMPITEYRRIQRIMSMCSSEFPAELVDRLEAAQD
DLEAQFEIGVEYAITQCQELIDAGVPGMHFYVLNRSQACKRIFDALGWHESAA
>A0A238KUB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagimonas varians|TrEMBL
MRPQISFEFFPPRNVEGTFRLWDAVQVLAPLDPRFVSVTYGAGGTTRDLTRDVVATLHKH
SGLATAAHLTCVDATRAETLAIAQDFAAAGVSDIVALRGDPPKGANGFEPHPDGFANSVE
LIEALADTGEFNIRVGAYPDIHPEAANAQADIDWLKRKLDAGASEALTQFFFEAETFLRF
RDSCAKAGIDKQIIPGILPIENWKGARNFAQRCGTPIPTWVDDAFGKAARDGREDLLATA
ICTELCSELLDEGVENLHFYTLNRPELTRDVCFALGVTPKAKLENVA
>A0A511KE02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosporidium toruloides|TrEMBL
MVKISDKIKKAEREGRPWWSFEFFPPKTPEGWVNLYDRIERMQQLGPIFVDITWGAGGST
SEATTNFVKTAHSELGLETCMHLTCTNMPVEMVDKALKASLAEAYDSGCRNILALRGDPP
RGVEEWKPTEGGFNHAIDLVRHIRKNYGDYFCIGVAGFPEGHPQSESPEAEIRHFKKKVD
AGADIVFTQMFYDAEVFIDWGRRLRAAGITIPIVPGIMPIQTFAAFKRRTDFAGTIVPKE
LWDLLEPIKDDDAKVREVGTKYVADMCRKILNAELGIHGIHCYTMNLSRGTEMLLEEMHF
VPTADRVKPLPWRLSLTQKRRAETTRPIFWSNRQKSYITRTRDWDEFPNGRWGDASSPAF
GDVDALLLALPHKPQDAIKIWGTPHSLGDIAALFARFCRGDLKSLPWSDQPAAKETTRIA
EQLARINELGFLTASHINSQPRVDGAPSEDPAVGWGPIHGYVYQKAYLEFFCPPELVEPL
LELLGDTPSVTYHAVNKQGDFRSNTAPGPNAVTWGVFPGAEVIQPTVVDSTAFQAWKDEA
YELGSQWAQLYKGSEPETYEVIERIFSEFHLVNIVFNDYRNRDEDAIFKPFFELAHQKGL
SIANGH
>A0A0P1EVW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobacter stenotrophicus|TrEMBL
MPAPTVSFEFFPPQSLEASFRLWETVRTLAPLDPTMVSVTYGAGGTTRALTHEAVATIHK
HYGLRVAAHLTCVDATRAETLEIADQYAAAGVTDIVALRGDPPKGSGQFTAHPEGFRHSV
ELIEALSSTGKFNLRVGAYPDRHPEAQNDMADIFWLKAKIDAGACEAITQFFFEPETFLR
FRDKCADAGISAPIIPGILPIENWAGTKRFATRCGTPVPAELDAAFETAIRDGREELMSL
AHATELCSTLMDEGVDHLHFYTLNKPELTRDVCAALGVTPEVKLEEVA
>A0A2M8E820|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium CG_4_9_14_0_8_um_filter_60_18|TrEMBL
MHTRTRFPISVEFFPPKSPEGVEKLRVVRQQLYALKPEFCSVTFGAGGSTQEGTFSTVSA
ILDEGVAAASHISCIGATRERVREQLATLKTMGVKRLVALRGDLPSGFGTGGEFHYACDL
VAFIRAETGDDFHIEVAAYPEMHPQAKSPEADLRAFATKVQAGANSAITQYFYSPDAYFR
FVEEADALGVRVPVVPGIMPIASSSQLMRFSDACGAEIPRWIRLRLQSFGDDSASIKAFG
LDVVTDLCEQLRAGGAPGLHFYSMNQSAAVLEVCMRLGLQRP
>A0A1H5L7Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium GAS188|TrEMBL
MGDRAMMPASQVPQDVVPPQAQDTVPTQAQDIVSQIVAFMQRASMEATRPTPADAEMLSA
VLPHGTDIFLSAVPRRPRGEVIAAARAIRTAGLNPVPHIAARAYPSLEAAREHLARLRDE
ADIRALLVIGGDLDQPAGDILEARQLIESGVLPALGIERVGIAGHPAGHPRMSDEELESV
LVTKIAAAQSSGLEVEIVTQFCFEPATIIDWIAWLRRRGVNLPVRIGLAGPTSLMTWLNY
ARRCGVRASAEGLARRSGLVKHLFNAVAPDSILRALAQARQAELPSTDRLGDVSAHFYSF
GGIGPTARWVASAMHGAITLDKEGGFQVEHE
>A0A327SP40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DpondAA-E10|TrEMBL
MRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTREGTVRA
TQQIAADSTLTPVAHLTAVDHSVAQLRNMVGQYADAGIRNILAVRGDPPGDPMAEWVEHP
EGVRYAADLVRLIKESGDFCVGVAAFPERHPRSADWDSDIRHFVDKCRAGADYAITQMFF
HPESYLRMRDRVVAAGCDTPVIPEVMPLTSVRQLERFPQLSNASLPSALKDRILAVKDDA
AAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A085ZVG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium luteum|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEATPGGHSSAMDLVHQINDLGRGKYLHNEDQICDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVTKAREMGITVPIIPGI
KPIATKKHLKLLPQVFKIDLPEDLINAVESAKNNEAVKQIGVEWAINQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A0S8JPR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division BRC1 bacterium SM23_51|TrEMBL
MTAETGQLQRVLSEGQLAIVVECIPPAARQAPDAEAVKKTAAVLRDKVDAVGVVDNRSEI
LMSAVATAAILQAEGIEPIVNVTTRDRNRIALMSDVIGARALGLRNFLCTSGDHQTLGRE
RAARNVFDLDSIQLLATLDRLRRDGVVFGDESQAGSLSHRPCDLYLGAVASPDADPQELQ
AIRLAKKVEAGADFLITQPVFDVDRFGKWLDSLEPSQIAEKAAILAGILVPPSAARTREI
RENVPAGWRVEIPDAVIERLESVRPEQQRDEAISLAVELIGRLRALKDIRGFYLMTDGDA
AAAVEVIERAGLRSDR
>A0A1I1SBC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax konjaci|TrEMBL
MSLSAGSPAFPVSFEFFPPKTLEGADKLRAVRQQLYVRKPEFCSVTYGAGGSTQEGTFGT
VREILEEGVQAASHFSCIGATRESVRTQLAQLKAMGVSRLVALRGDLPSGYGAGGEFQYA
SDLVAFIRAETGDDFHIEVAAYPEVHPQARSPEADLQAFAAKVRAGAHSAITQYFFNADA
YWRFVDDVRALGLDVPVVPGIMPILGSTQLMRFSDACGAEIPRWIRLRLQGFGDDSASIR
AFGLDVVSALCERLRAGGVPALHFYTMNQSAATLELCRRLGL
>A0A845IVB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium japonicum|TrEMBL
MSGAMTDLTTPARAEGQDGHLQNGHLSSKRPAISFEFFPPKTEEMERNLWETINRLAPLD
PKFVSVTYGAGGSTRERTHSTITRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVR
HIVGLRGDPAGGIGTPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDA
DIDTLKAKVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFV
TRAGTTVPDWLAEKFDGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVF
AISHLLGIRAKSAQKAA
>A0A7J5DHA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces triticiradicis|TrEMBL
MALGSASTRTDRARTVRDMLATGKQTFSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVLDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSTEWDLDVSHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCGTPVIPEVMPVTSVKMLERLPKLSNASF
PDVLKERILTVKDDAAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A7V9ARC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MRIDQILDERRPVFSFEFFPPKDDEGMERLRGTLTELRVDEPSFVSVTYGAGGSTRERTI
EITREIKEDFGIEAMAHVSCVGTTVEDLRGVLDEVQAAGIENVLALRGDPPRGQTEWRPH
PGGLSYSTELAALMADGYDFAIGAACFPEVHPEAPDMEHDLRFLKEKIAAGAGFLITQLF
FDNDFYFDFVDEARAAGVTVPIVPGIMPITNFAQIKRFTEMCGASIPEGLERELFARADD
AEAVTELGVAYATLQCSELLARGAPGIHFYTLNKSPATRAILAALRAARPWDRALAPAT
>Q88D51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)|TrEMBL
MQLAARRLLPEERLMSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGG
STRDRTLNTVLQLESEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSG
MGMASGELRYASDLVEFIREETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADS
AITQYFFNADSYFYFVERAQKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQL
EAYADDTASIQAFGEEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7X7G011|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MKTLTDLFSSRPRTFSLEIFPPKTEKGLLALEAALKELAGLGPDFISVTYGAGGGNRDRT
LGLVRLIQERHNILALHHFTCVLHTRKEIRGILDHLQKVKVRSLLALRGDPPKDRPDWVP
GPENFRYSSELVAFIREHYGDSFSIGVAGFPEGHPLAADKDADARVLKAKIESGGEFVIT
QLFFDNALYFDYVRRVRTLGVTARIIPGILPVTSYEGVVNFCKGCGASVPDKVHDIFSPI
AQDPDKTREAGIRFAIDQCRELLARGAPGIHLYTLNKAEPATQIVSELRRMSL
>A0A8I0AKK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. NSJ-10|TrEMBL
MKIRDIIGQEKATLSFEVFPPKKDTDFASVEAAALGIAALRPSYMSVTYGAGGSTKGHTI
KLANEIQEKYGVPTIAHLTCVCANKDSIRTALSEMKNAGIENILALRGDIPKNYDGQVFT
DFAHASELVKLIKESGDFCVGGACYPEVHPDSANKQDDIANLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRIREAGIAVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEVAAGIQANLSDILLV
>A0A7X9A796|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
EVGIEVMPHICCRDRNIIALKADLLGAYTEGIRNVLIITGDPIPCSERNETKSVFDLNSI
RLMELINTMNQEQFAADPMKIAGGLNLNTDRKDIQMMRAEKKAKAGAQIFLTQPVFEEGA
IDYLAQLKKREGTKILGGVMPIVSRRNAQFLNNEIPGIRIPKEYVNSFAPDMPKNKARDA
GIEIALSIVKKIMNSIDGFYFITPFNRADMIVKILKRTF
>A0A7X7AN33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MGNKFKESLLDKNSFSVTWELVPGRGARETPQEAAVAAAQQAAKGKRIHALTITDNPGGN
PAMLADYLGLEIFQKGIEPLVHFTCKDKNRNQMESQLYALDRAGVRNLLVMTGDYPVTGF
KGRAKPVFDLDPIHTLELIENMNKGLEYRDLKGTVKHQPSDFFAGASVSPFKATEAEQLL
QYYKLKKKLEAGAKFIVTQVGYDARKFHEVLLYMQLHGWDVPLIGNIYILPFGVARTMNA
NRIPGCVVTDKLVAELDEERQAPDKGVGERLLRAAKMYAVLKGMGYRGVHIGGFNVKYEQ
VEYVIEKGEELAPNWLDYVRDLDYPIPGGFYYFEKDEKTGLNVEKPMNRKGRPLEAPVEY
VYPLSRFVHKLAFEPDKNLFSLMQGLARRVEGSSLEKTYHWFEHLAKVLLYDCKDCGDCA
LLDLAYLCPMSQCPKNQRNGACEGSYHGWCEVYPQERKCAWVRAYARLKKYEEEDNLQAY
TVAPCNWDLYQTSSWLNFYLGKDHSAARLGIAGRPKKRKEEK
>A0A1Y3R6F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes onderdonkii|TrEMBL
MNVVDIINKAVEQRRTRFAFELLPPLKGDGMGGVFESIDRLIGFDPAYINVTFHREGIKQ
AVRPDGSVEWHVVRRRPGTVGISAAIQKKYGVEVVPHLICGGQSKYDIEDALIDLDFLGL
HNVLALRGDKSQNEKFFMPHPQGHTHAVDLVRQIAAMNRGQFVDGEVEECHHSKFSIGVA
GYPEMHEEAASPEADIACLKAKVDAGAEYVVTQLFYDNARFFDYVRRCREAGITVPIIPG
IKPLSTVRHLTLLPRTFGCHIPEELEREVLRHKDDPKAVREAGTEWAVAQSRELVEAGVP
VLHYYPMGKADNIIKIAKAIF
>H8Z1A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiorhodovibrio sp. 970|TrEMBL
MTKHLQDTLSFEVFPPKTDEGMTKLKRAVTQLNQLKPLYFSCTYGAGGSTRERTFETVSW
LREQGIETAPHLACIGSGKEEIRDIVEHYSQQGITRLVALRGDLPSGMGRPDRGTFRYAS
ELVAYLREAYGQQFSIEVAAYPEFHPQAASASADLEHFKHKVACGADTAITQYFYNADAY
FAFVDACEKQGIAVPIIPGIMPITNYSQLARFSDACGAEIPRWIRRRLEAFGEDREAIRA
FGHDVVLKLCERLVAGGAPGLHFYTMNQAKPILALCTDLGVTPKLAGDAAAD
>A0A565BNU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabis nemorensis|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGSDK
FVQVEGGFGCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIGENGLATSEAYQSDLEYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGIKCPIVPGIMPINNYRGFLRMTGFCKTK
IPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKEFCLGNLKSSPWSELDGLQPE
TKIINEQLVKINSKGFLTINSQPSVNAEKSDSPTVGWGGPGGYVYQKAYLEFFCSKDKLD
AVVEKCKALPSITYIAVSKGESWVSNTAQSDVNAVTWGVFPAKEIIQPTIVDPASFNVWK
DEAFETWSRSWAGLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIFAVFAGL
>A0A3C1MUR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTPTTFSFEFFPPKTPEGMDKLRATRDQLARLKPKFFSVTFGAGGSTRDFSLETVLDIQR
AGYEAAPHLSCIGSTHVNIRAILQEYQNHGIRHIVALRGDLPSGMASTGEFRYANELVEF
IRSETGDWFNIEVAAYPEYHPQARSARDDLLNFKRKVDAGANSAITQYFFNADAYFNFVD
EAAALGVNIPIVPGIMPIGNFSQLARFSDACGAEIPRWMRKQLEGYSDDIDSIRAFGLDV
VTDLCERLLKGGAPGLHFYTMNQAAATTEIWKRLGL
>A0A070A3G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataeibacter rhaeticus AF1|TrEMBL
MGLTAVELIPRDRETLLRDAGEVSQHFPDAQLINIPDLLRFPLRSWEAARLIRPIFPRVV
PHVRAIDIAPDAPLPGADDPGLREVLVVEGDPPTDLRHRTYPNTSESVIARYRREAPHLD
VYAAFDPYRRAPYKEMQAIERKKEAGAMGFFTQPIFDMRMLDLCMNWLEGETVFWGISPV
IGPRSRSYWETTNHVIFPHDFDPTLEANIAFARQMMDTVAQAGGNTYLMPLRVKLERYLI
PLRRA
>A0A1H7AL39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Demequina mangrovi|TrEMBL
MTIRDLLAQPRPTLSYELFPPRTPAAESTLEETMRMLAATRPDFMSITYGASGSTRGTSR
GVVHRLAVEHTIPPLAHLTCVDQSRAELVEVIETYLAEGVRDFLALRGDPPRGQADWRPH
PDGLLYASQLVELLREVAHAHGVDDLSVGVTAFPAQHAKERYRQLGLDVLRAKRDAGADF
AITQVFYEVSQYVALVEDAREQGIDLPIIPEVMPLVSERRAIRAEELTGVETPADLFAAL
EGAPDEDAARAAGVAHAARLSRDLLEAGAPGIHIITFNQHRAALELVDAMGLVRD
>A0A2Z4K4R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. KY5|TrEMBL
MTPTLNQLHEAKTALDAPLFSDLPGDIDISFEFFPPKTEKMGETLWSSVATLSPLGPRFV
SVTYGAGGSTRERTHEQVVRIQKEAGIPAAAHLTCVNATKDEVDEVARHYWEEGIRHIVA
LRGDPPDGASAYAPHPGGYENAADLIAGLKKVADFEISVAAYPEVHPDSPDAQADIENLK
AKFGAGADRAITQFFFDPECFFRFRDEVAAAGITAEVVPGIMPVMSFAAVQRMSAMCGTA
IPSWMEGLFDGLDERPAARQLVSATIAAELCRKLYAGGVRQFHFYTLNRAELSYAICHML
GKRPAGDTA
>A0A0G9MVV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantiacibacter luteus|TrEMBL
MVDGYSLEMTAKEIDGLREAAPLIRPDTQIAVTFLPGEEIEQRIEASSVVRELGFEPIAH
VSARRIRSHEELDYYLSETARRAQAKRIFVIAGDPPEPEGPFEDSLQIIETGLLEKYGYQ
VIGVGGHPEGHPNVDKDALWTWMKRKLDAVRARGMTPLIVTQFAFDDDAIVEWLGEMRRR
GIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGVSITNLIGTAGPDKLVDNLDK
KLGQEHGRVRLHFYPFGALSASAEWINDYDARHS
>A0A1H6Y7E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Demequina mangrovi|TrEMBL
MHRTATLLEDLSVEITARDTATLVAHAGDLPAGTRVSVTHLGTEGAPERREAAAAAARAE
LVPVPHLAARRLGSESELRDALDGLRAHDAHERLFVVGGDPRTPAGPYASALDVIRSGLL
AEAGVAEVGITGYPEGHPAIADEALWAALRDKTAAIADQGLTASVTTQFSFDADAVVAWI
ERARALGIAAPIRVGVPGPAGVRRLVAFARRCGVGTSAGIARKYGFSLTSLVGTAGPDRF
VEELTSRLEDAHGEVRLHLYTFGTLAATIDWARAAREAAVPAERP
>A0A1R2CNL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stentor coeruleus|TrEMBL
MKIIEAIEKCKDDGTFPFFSLEFFPPKTEEALFNLHQRIERMSQSLGPLFIDLTWGAGGS
TFKESLELSSWIEQYSGCEVMMHLTLTNISLDIIDQALSKAKEAGICNILALRGDPPRGQ
ERWTHSVENFQYARDLVRYIREKHGNYFGICVAGYPEGHTECSDIDTDIANLKSKVDAGA
DFIITQLFYDVDMFLKFVSKCREIGINCPILPGIMPIQSYQGFHRMVSMCKVSVPQYILD
KLEEIKSDDDQVKAFGVEVAVQMCKKLLANGIQGLHFYTLNLERSVTKIIQELKVVKLGR
EAPWLRPANRNQEWVRPINWSKRPKSYIERTTNWDDYPNGRWSDSRSPAYGFSFSGTNAN
YTNKQKEALRAMWGHPLTIKDLSTVFLNFLNGQISRLPWFEEQGLQTETLMIKDFLINLN
QYGLFTINSQPKVNCASASDPKVGWGPRNGRKGGYVYQREYIEFFCSRDSLNVITTILNN
YPTISYIAVNILGEEISNITEGDVIAMTWGIFPNREVLQPTILDPYIFKTWWKDEAFGVW
ANEWGEVYTRDSESFALLQNVKSSYYLVNVLENDFVEGNLEKVFTEVLGSLTRL
>A0A3D1WEF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MESTSRQFSFEFFPPKSAEGAVKLRETVTQLGQLNPAFFSVTFGAGGSTQEGTLKTVNDI
RAMGYNAAPHLSCIGSTVESIREIVHRYRDAGIRHMVALRGDLPSGMAMAGEFRHASDLV
AFVRTETGDHFHIEVAAYPEYHPQSRTAQEDLKNFKRKVEAGATSAITQYFYNPDAYFHF
VDEVRAMGIDVPIVPGVMPIGSFSQLARFSDACGAEIPRWIRRKMEGFGDDSASIKAFGL
DVVTDLCQELLEGGAPGLHFYTMNGAGASTTIWQRLGLS
>A0A1M7B6E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius marisflavi|TrEMBL
MIDSGAHGADLLAYSKPPEGHVSHSRLERVLRSGRFAVTAELNPPDSADAADVFEAAQPL
GEVADAINATDASGANCHMSSIGICALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAALG
VSNVLCLTGDGVGVGDQPGAKPVFDFDSLTLLRTIRTMRDKGVFLSGRKITRPPLLFLGA
AENPCIQPYEWRPDRLIKKIEAGAEFIQTNYIFDIPLFEKFMARVRDEGADKRVFIIAGV
GPLASAKAARWMRSNVPGIHIPDHVIARMEGAANQSEEGKKICIELMQQLREIEGVAGVH
IMAYRREHLVSSIILESGVLSGRRSAKRR
>A0A6B2U893|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID13031|TrEMBL
MATGLPSTLPGTTPTIRDLLSTAEPSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVSHSRDELRSVIGAYAGAGVRNVLALR
GDPPGGPSQPWVAHPEGLNHAVELVELVRELGDFCVGVAAFPDKHPEASDLETDARVLAA
KAAAGADYAITQMFFGADDYFRLVDRAAALGCDIPILPGIMPVTNIKQIERMAELTGMAL
PTAVTDRLHAVADDPAAVRSAGIEIASELCDQLLAGGAPGIHFITLNRSTATRQVFRNLQ
STVV
>R5KE55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:632|TrEMBL
MIKDIFQTGRTVYSCEVFPPKRNDDIYSIFKTLDEIQTCRPDFISVTYGAGGSTSKKTST
IAAYIQNICEVEALAHLTSVAMDEHFLRHMVAELNKKGVHNVLALRGDQPRDMSDEDFAN
RHFKHASDIIPIIRDAASSDMCIAAACYPEKHPESASVEEDLKHLKLKADTGVHFFITQM
FFDNQKFLQFREAARAHGIQTPITAGIMPITSVKQIGTSIQLSGSSVPTELSNLFAKYGD
SPEDMKKAGIDYAIRQIQELIENEVDGIHLYTMNKSDVTKEIFGQVKPQ
>A0A7C9FWQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. BE17|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTDLCRRLIDAGVPGLHFYTLNAATATRTICERLGV
>Q03BF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei (strain ATCC 334 / BCRC 17002 / CCUG 31169 / CIP 107868 / KCTC 3260 / NRRL B-441)|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A7M1S7N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum indicum|TrEMBL
MFETFCDFLCNKTKKFITVEINPPHGASLDGIIEDIRKHNLHEKVSGFSCTDNPLAKLKM
SGVLSAIKVQQTFGKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKLSDQP
EVKGVLERDSTLLLSIIYHLNNGVDYSNKPLNPAPRPIYPFAVSNSYAKDMKKLQKRMLK
KLNYGARAIITQPVYDLENAKELLALFEEAKEMSIRETAKEAQLVLGQFPIVRARTANFI
DDKVPGISVPKGIIDEMNLAAMDGEEKEQEIGFALSKSIFDEMMKLHGKVHLMTHNRFDL
CSDLIGELSTSHN
>A0A839YMH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. BK580|TrEMBL
MTFSVNQLEEARRALDAPLYADVGGDVDVSFEFSPPKSEKSEETLWQSIETLCPLGPRFL
SVTYGAGGSTRDRTHATVARIARETAVPAAAHLTCVEATREEIDAVAQEYWAAGVRHIVA
LRGDPPAGAADYAPHPGGYENAAALVAGLRRLHPFEISVAAYPECHPSSADLAGDLDNLK
RKLDAGANRAITQFFFEAETFFRYRDAAAAAGIDAEIVPGIMPIGSFAGVQRMAAMCRTD
VPGWLVRLFDGLDDLPAARQLVAATVAAELCRKLYAGGVKQLHFYTMNKAELSYAICHLL
GVRAAPRHAAAAA
>A0A7R7IDY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium TB5|TrEMBL
MLIRDYLKTHKLIMDGAMGTYYSKLVNDESAIAERANLQNPEIILNIHKEYIASGAKLLR
TNTFVASKEILEITEAEQRKLIKAGYQIAKEAAESSSEEVYIAADIGPIPENAESEYEDI
LSEYKVLIDSFLEVGATIFLFETFSDIKYIAPLVKYIKQDKESDIFIITNFCLNKNGYTK
SGLSAKRLLEEIRDIKEIDAVGFNCGIGSGHMYQILEGLTFPSNKYLVSAPNSSYPEQYQ
NRLVYLDNANYFKDKMQKIAALDINIIGGCCGSTPLHIKGLDTMIDMQNHRVLSEYSADN
IENIVTEQRKNEFYEKLKSGKKVIAVELDPPFDEKYDKVMECAHQLKEHGVDMITMADSP
MGRSRVDSILMSLKLKQELSIPVMPHVCCRDKNMIAMRSGLLGAYINGIRNILIVTGDPV
PSERKKETTSVFDYNSIQLMDYVKEMNKEHFSEEPIYYGAALNYGRGLIDKVIERMNKKI
AAGASYFLTQPIYSDEDIDRIREIKSRVDTKILCGIMPLVSYRNANFIKNEIAGIHVPDD
IVNRYHMDMSKEEAEMVGATISNEIIEKLNPFADGYYFMLPFNRVSLMDKIKID
>A0A1V5Q686|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin354|TrEMBL
MKISEIYKDGHPTLSFEVFPPKTSEVYDSVVKATNEVAALKPDFMSVTYGAAGSTRTYTT
AIASNIEKSGVTALAHLTCVNASEESLKEQLESLSENGIHNILALRGDLPAGVESTSDWV
FKHASELIPIIKKYGDFCVGCACYPEKHPESKDIKEDIEGIRKKVDAGCEFLTTQMFFDN
ALFYNYMYRLREAGITVPVTAGIMPVTRAKQMERIISLSQAFIPRRYVAILDRYGDKPEA
LKQAAIAYATDQIIDLLANGIEHIHIYTMNKADVAQKIQENLSDIIPSCKKS
>A0A415J112|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola plebeius|TrEMBL
MKVIDLIKNSKEPVFSFEILPPLKGNSIQKVYHIIDKLREFDPKYINITSHHSEIVYLPQ
PDGNLKKTTVRKRPGTVAIAAAIQNKYGIQAVPHIICKGFTKEETEYALLDLNFLGINNL
LLLRGDSKPLDIAEKDLCLYHEHATDLQEQVNRFNQGIGLDGSKIEGIETPFSYGMACYP
EKHEEAPNMESDLFYLKEKVRNGADYVVTQMFFDNEKYYAFVERCRQEGIDVPIIPGVKP
VVFKNQLNVLPKVFRTDIPEAFASELRKCTTDEEVKAVGVEWCKAQCKDLLAHGVSGLHF
YTFMASDSVYKVAKEVY
>A0A3S1HND4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.T.Ca.TU.009.01.3.1|TrEMBL
MIGRQIDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRSYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A2W4CIG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium tubonense|TrEMBL
MAHIDENPLGPHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERASIF
NGWVDGINAVDASGANCHMSSVGICALLTRIGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANMMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTKPPQVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLDEKCFILVGV
GPLASARTARWMRSNVPGVHIPDAIIERIEGAADQKKEGKQLCIDIINEVKEIAGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRRPWQREASRDDAIVAERREHIREGQAENQQELAELAA
HHPPHYTPAN
>A0A1V3GRD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinivibrio sp. ML290|TrEMBL
MSYTHAGHIDALNQNIADLDGDINVSFEFFPPSTPSMEETLWNSVHRLKALKPKFMSVTY
GANSGERDRTHDIVKSIHDQTGIAAAPHLTCIDATEDELRHIARDYWQNGIRDIVALRGD
LPSPEKKPDTYAVDLVRLLKEEHDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAKMTNVRVPQWMHKQYQ
GLEDDPVTRQMVGASIALDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPLAVTP
>A0A0Q8PQL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root190|TrEMBL
MVTGAGRSLGEIIREGGRSFSFEFFPPKDDKGEVQLWDAIRALEPYRPTFVSVTYGAGGS
TRDKTVAITGRIARETSLIPMAHLTCVGHTREEIEGILDAYDAEGVAHVLALRGDPEEGP
RADWTPTDGGLNFAVDLVELTRARGTFRVGVAAFPEGHPSASSLDDDADVLVAKAKAGAE
FAVTQMFFRASDYFALVERVRDRGVDIPILPGIMPILNLSAIRRQGELIGTSVPQEIVDR
ISAFDGDPAAVRAEGIRIAAELCDELLAGGAPGLHFYTLNRSKATLEIFEALQITV
>A0A398B0X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesobacillus zeae|TrEMBL
MSFLEKMKTEILIGDGAMGTLLYSFGTGSCFEELNLSHPEDIVRIHQAYIDAGADMIQTN
TYAANYLKLQRYGLEDSVKEMNSSAVRLARQAAQQKAYLLGTVGGNRGIRPSAIPLDEIK
RSFREQLYCLLLEGVDGILLETYYDIEELETVLKIARRETELPIIAQISLQEIALMEDGT
SIGDAFDKLEGLGADIVGLNCRLGPHHMIASLEGVELPKKAYLSAYPNAGLPSYTDGRFH
YEGNPEYFRKSAQSFRDQGVRLIGGCCGTTPEHIRAIESELKGLAPVTHKKVIGRKAKIV
VSPPEVIRKERPLEEVVKERPSVIVELDSPRKLDTTRFFQGAKALKEAGIDALTLADNSL
ASPRISNKSIGHLVKEKVGLRPLVHLTCRDRNIIGLQSHLMGLHTLGLHDVLAVTGDPAR
VGDFPGASSVFDVSSFELIEMIKQFNEGFSYSGKDLGQKGAFSIGAAFNPHVRSLEKAVS
RMEKKIKCGAHYFITQPVYSEKLLLDVYEATKHLDVPVYIGLMPLTSSRNAEFLHNEVPG
IKISQEILDTMAKFNNDPVSSKKEGIAITKGLIEAAAELFNGIYLITPFMNYEMSVELAN
YANECSSLLSRRKQNVNYVN
>Q9RA47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus thermophilus|TrEMBL
MKIRDLLKARRGPLFSFEFFPPKDPEGEEALFRTLEELKAFRPAFVSITYGAMGSTRERS
VAWAQRIQSLGLNPLAHLTVAGQSRKEVAEVLHRFVESGVENLLALRGDPPRGERVFRPH
PEGFRYAAELVALIRERYGDRVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIGIPILPGIMPVTSYRQSAASPRSAGRASP
>A0A7X2TJL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. SMMA_5_50|TrEMBL
MTTPAISFEFFPPRNLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETLQIVSDYAAAGVHEIVALRGDAPQGQDRFVPHPEGFANSV
ELIEAIAARGDMTIRCGAYPEPHPESPDTAADVAWLKRKVDAGASSAMTQFFFDAETFFR
FRDACVAAGISAPIIPGILPIQSWSGTRRFAERCGTSVPQWACDAFEAAGKEGEGQLALD
ICVRLCQQLIQGGVDRLHFYTLNKPELVGQVCAALGIEPRAEFPRVA
>A0A1H6Q7M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. 45|TrEMBL
MSGLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPEKVLAIHKAYIEAGADVIQT
NTYAAKRHRLEGYGYGNKVKEINQAGVKIARQAAGEDTFVLGTVGALRGLKQCELTLDEI
IKETLEQVGYLLETKGIDGLLFETYYDEEEIVEVLKAVRPLTDLPIITNISIHEAGITEN
GRPLVEIFGKLVMLGADIVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAIKGLKPVSRKFVTP
MVEEAELIKAVKQSETIVDKVKRKVTIIAELDPPKTLDIRKFTEGVKALDEAGVSAITLA
DNSLAKTRICNVSIASLLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIKQLNKGIGYSGASIKKETTFTAAAAFNPNVKNLS
RCGRLIERKIAAGADCFITQPIFNSEIIENLAELTRDYETPFFVGIMPITSYNNAIFLHN
EVPGIQLSDDFLAKLEAVKDDKEKCQQLALEESKQLIDHALKFFNGIYLITPFMRYDLTV
DLVEYIHQKVEQSHQIIP
>A0A7C5PIH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MSTETFRQALTSGRFLYGAELVSTRGIPAPGESSKLIELGTALVADPRIAWVSITDNPGG
NPMLPPDWIAGQLGANREKIVIHLTCKDLNRNGLESAAWRYAAQGFNNILALTGDYPVTG
YGGLARPVFDLDSVSLIAMLKAMNDG
>A0A7Y9KB62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura citrea|TrEMBL
MRRVRPDRPPTVRELLASGERSFSFEFFPPKTDKGARNLWRTIRELESLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAVGVRNVLALRGDPP
GDPMGEWVKHPDGVEYAAELVRMIRSYGDFSVGVAAFPYKHPRSRDIESDTRHFVAKCRA
GADYAITQMFFRAEDYFRLRDRVDAAGCDVPILPGIMPVTRLSTIERSEQLSGAPFPPEV
RARFEAVADDPEAVRRLGIEHAAELCCELLDQGAPGIHFITFNQSTATREVYSLLDGAGY
GARGSVPPITA
>A0A349GXN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MKHHISNKIFHVEILTPKQNSEKLDADLEAFCDKYNKVIEAGYVACITDNPMGNLSFQAT
EVIPECDLPVNPEQLVIHLNTFHTREHLDTILTTAADMGAKYLLTLSGDGSERLAKLTPE
SLGMNCNTITSIELLQYIHKAYPNTFSCGVAFNPYEPAEHELERLERKLEAGAEYIITQP
VIGNDPLVASLKKYNVPVIVDAWMSKKLHLLSECVGYEIPEDTPYDPIDNLGKLQEYYPD
YGLYLALLGFKSQYPLLKEIWK
>A0A3M1GA65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
VYYRFVERCRARGIEVPIIPGIMPVLSLKQIRRMTELCGSTLPRKLERRLELAAGSADAV
EFVGLEWAVTQIRDLLANGTPGYHLYVLNRAKSGLALAAGLVD
>A0A2V6C8T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
LEQCHDLLDNNVAGIHFYTLNRSDATRIIFDSLGIPRRRNAQAQTV
>A0A2V5Z6M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRGNSPTFSFEFFPPKTPEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQRTTKLDPIPHLTCVCHNEQEVEEILLRYAKSAIGNILALGGDRPAGIAYDKSR
DSFQHAIDLVKFIRRFNESGAHPDHRGFGVG
>A0A139PBW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. DD11|TrEMBL
MVNRQTPSLSFEVFPPNPAVGNEKILQALKEMQDIAPHFISVTASNNKFNIEETTVRLAD
FIYNDLKIPTIAHLPAVYLTKDRVSHTLQALDRVGVHSVLALRGDIFPDVAPKDDFRYAT
DLIAYIKEEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAIDQIVDLVTHDAAGIHLYTMNNSATARHIYQATHTFFDK
>A0A2V5LY30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRANSPTFSFEFFPPKTPEAAETLYQTIRDLESYVPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIQAILLRYAKSAIGNILALGGDRPAGIAYDKSR
ESFQYAIDLVKFIRRFNESGAHPERRGFGIGVAGFPEGHPATPNRLVEMDYFKAKVDAGA
DYVVTQLFFDNRDFLDFRERCALSQIHVPIIAGIMPITSITGCKRMAELAGGTRFPATLL
RALQHCQNNPEMVRRVGIQYALEQCHDLLDNDVAGIHFYTLNRSDATRIIFDSLGIPRHP
NTPISTV
>A0A3D3LXL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp|TrEMBL
MSTYTPALSYELFPPRSSASCENLLTTIGQLAPTNPDYVSVTYSGDRARKQKTLALLDHL
VHETQLTPLAHLTCVGHTAEELEAAVRCILAIGVRGFLALRGDLPPGNTQAPDIPFARSL
VDLIRRVETQDFAHLAAGRVAVGVAAYPSRHPESSSELQDIEILLSKERAGADFAITQVF
FEATRYESLVQRARTAGVTLPLIPGIMPVTSLRRLTTLCSLAGLPVPQQLAYDLETASGD
AQRHRIGVEFSARLLQESLDAGAPGIHFYTFNEHAAVLDVLEQVNLPRYSTRFENPLAEL
TYA
>A0A1H9JFM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. yr375|TrEMBL
MSVTYGAGGSSRDRTVEMTERIVNETTLQPVAHLTAIGHSTAELRRIIGQYADAGVRDVL
ALRGDPPGDPNAHWSPHPQGLRYAHELVALVRESGDFSVGVAAFPERHPRSPDWESDIRH
FVAKCKAGADYAITQMFFHAEDYLRLRDRVSAAGCDTPLIPEIMPAVDIRQIARFAELSH
ATFPDDLARRLEAARDNPAEGRRIGVEYATTMADRLLDEGAPGLHYITLNRSTATLEIHR
SILDSRSTHALAHG
>A0A0P8BLA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phormidesmis priestleyi Ana|TrEMBL
MTLTHSEAQNGAQNGAQNGTQNSTQNGKAPLRSNPGHGKLRSAVRSREFVVTAEVMPPKG
GDPSHMLEMANHLKDWVHAVNVTDGSRAVLRMSSLACSVLLKQAGIEPICQMTGRDRNAI
ALQADLMGAHALGIHNLLALTGDPVKAGDHPKSKPVHELESIRLLQVIAQLNSGFDYHDQ
AMPDGQLDIFAGAAVDPQSSSWSGLQRRFDQKLAAGAQFFQSQLISDFDQLEKFMDQIAA
GCDRPVLAGIFLLKSAKNAAFINRCVPGVNIPEHIINRLAAAADPLQEGIKIAAEQVQAA
RQLCQGVHMMAVRREDLIPQILQMAGIEPQIQASSVGLLSTAQ
>A0A0Q6F8W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmoricola sp. Leaf446|TrEMBL
MRRLLEHARYEVLPTATTEDKVVAAVPTDVAVTVTASPGKGLEATLALSETLAGHGYAVV
PHLAARMVRDHAELVDIRARLRAAGISAVFVPGGDAEPAGDYTDAFSLLEDLATLADPFT
HVGIAGYPESHPTIADDLTVQAMWDKRRHATHVVSNLTFDAATIRDWVGRMRLRGITMPL
LLGMPGPIDRAKLLTMATKIGVGESTRFLAKHKGTFARLAAPGGFTGERFLRDCAVVAAQ
PTAGIEGLHVFTFNQVAETEAWRQKLLAELA
>N9GDU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter haemolyticus CIP 64.3 = MTCC 9819|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDADIKRFIEKVQAGANAGITQFFFNPDAYFYFI
ERLEKAGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLSAYGDDSASIKAFGHE
VILKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A0D0LH38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. MEB061|TrEMBL
MKVTEHIENAKGNTLFSFELIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKVGGNSFAIDLVRQINDLNCGKYLHEVMDAGNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFTFVEKAREMGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQIF
>A0A844Y7B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania pelagi|TrEMBL
MSPTLDQMREAQRALEAPMFSDLVGDIEVSFEFFPPKSEKMAETLWQSVETLKPLDPRFV
SVTYGAGGSTRERTHEQVVRIQNEAQIPAAAHLTCVAATREEVDAVARHYWEEGIRHIVA
LRGDAPDSEAGYAPHPGGYENAVDLIKGLKKVGDFEISAAAYPEMHPDSKDRQADLDNLK
AKFDAGATRAITQFFFEPECFFDFRDRAAAAGIEGEIVPGIMPVMSFAAVQKMSGLCGTA
IPHWMEGLFEGLDEKPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRPKADT
>A0A426SDH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseofuscus|TrEMBL
MRPGERSYSFEFFPPRTDTGERGLWQAVRRVEALSPAFVSVTYGAGGSSRERTISVTERI
RTETTLRPVAHLTAVGHSVAELRRIIGRYADAGIRDVLALRGDPPGDPQGEWSPHPEGLR
YAAELIELLKSVGAFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAVTQMFFRPED
YLRLRDRIAAAGCDVPVIPGIMPATSFAQIHRFAQLSNAAFPPDLAQRLEAVRDRPDLGH
RVGVEHATAMCERLLAEGAPGLHYITLNNSSAAVEIHRNLCPHRAAAPLSAA
>Q6CKM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)|TrEMBL
MRISQKLQRAHEEREDATFSFEFFVPKTSQGVQNLYERMDRMYQTQPEFIDITWNAGGRL
SMLSTDLVATSQGVLGLETCMHLTCTNMPVSQIDDALKKAYDAGCENILALRGDPPINSL
GEEEEWKPCENGFRYAKDLVSYIREQYGDHFDIGVAAYPEGHPECDCDDKLLLHLKEKVD
CGADFMVTQMFYDVDKFLDWCARVREAGISIPIIPGIMPITSYPSFIRRTQWCQINVPDN
FLELLEPVKDDDQLVRDVGTELMVELCQKLLDSGYVNHLHMYTMNLEKASLMILEKLDLL
KRSNVGKDVIEPLEPLPWRKSLNPKRRNELVRPIFWQKRPYSYVARTSLWNEDEFPNGRF
GDSSSPAYGDLDLCGHSLIRQSVKKSIELWSTPQTLDDMSNLVTSYLEGKLKCLPWSDVP
LNHEVDDILKHLIDLNKHHIFTINSQPKVNGKPSTDPVVGWGPTKGYVYQKEYLEFLLPR
EKLPLFQEICQEHSDHLTYFAIDSQDNLATNHPEDSRANAVTWGVFPGSEILQPTIVEKA
SFLAWKEEFFTILKEWKLTFVEHKATESVNLVNHIIDNYVLINVVDNDFISTNDTIYDLL
QQLY
>A0A1I9Z4F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia seriolae|TrEMBL
MVQQLGPRPDGSIPFSVEFNPPRDAAGEARLWRAAREFERLHPAFVSMTYGAGGSTRDRT
IRITGQLARETTLLTVAHLTAVDHSVAELRSIVGAYADSGIRNLLVLRGDPPGDVLGEWV
KHPEGVEYAEDLVRMVRELGDFHVGVASFPQGHPRSANLEDDTNFLVAKLRAGAEYSITQ
MFFDPEHYLRLRDRAIACDPVEGAKPIIPELMPITSLRTVERAVELCGRPLPPKVMERLH
KAAGDGPEENRAAVREVGIEIATEIAERLIAEGAPCLHFITLNFAKATGEVLANLGYSMS
PAPATV
>A0A3R7TAW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium TMED125|TrEMBL
MSLQHAPKDIHVSFEFFPPKSEKAEDTLWESVRRLEPVHPKFVSVTYGAGGSTRDRTHRT
VKRMVEETDLTPAAHLTCVSASKDEVMGVVDDYLDAGVRHIVALRGDPPEGMGAKFTPHP
DGFQSSVDLISAIRHYRPELGKRFEISVAAYPEPHPDSLGLAKDLEILKAKQDAGADRAI
TQFFFEPDHYFEFLDAARGYGIDIPIVPGIMLQPNFNGLKRIATLCGASLPAWLHELYEG
LEGDAEQRELITANVAADLTMKLADRGVKDFHFYTLNKAGLSLATCRLLGIKPDKQAA
>A0A329HGV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. RIT 418|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPEELRAIAQDYWNNGIRHIVALRGD
LPPGSGRPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGA
>R6BEH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:169|TrEMBL
MKLQTLFEEKKVVFSLEIFPPKKTSSIQTIYDTLDALRDIEPDFISVTYGAGGNPADRST
VQIASDIKHRYHIEPLAHLSCVNSTKEHIGRVLDDLRENDIENILALRGDLNPNVPPQTD
YRYASDLIDDIKQYGGFDIAAACYPEVHPEAADLEEDLLHLKEKVAAGATHLISQLFFDN
NDYYNFLYRVRQAGITVPIEAGIMPVTNRKQIERMVSLCGASLPKKFVRIMHRYGDDPAA
MQDAGIAYAVEQIVDLISNGVQGIHLYTMNNPLIAHRINQAVASLIRCSNR
>A0A6B3QKE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces tendae|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPGADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PPELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A3R8Q769|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseofuscus|TrEMBL
MGTDLLDDFSLEMTGKDVPALEEARGSIPQGTRINVTFLAGEDHATRLAAARAVRGLGFV
PVPHISARRLPSSAALEGFLAGLAEDGTADNVFVVGGDPARPEGPYEDALAVLRTGLLER
YGVRHIGISGYPEGHPAISGPALWSALTDKARAIGAGPFTGDVITQFGFDADPVLDWLAA
VRARGVDLPVRIGVPGPAGIRRLVGYATRFGVTTSASVARKYGFSLTNLLGTAGPDRFLH
ALGERYDPARHGVVKVHFYTFGGLRTTAEWVGGFRERTR
>A0A1L7CGW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium aquilae DSM 44791|TrEMBL
MENYQLGITDVLRRTPAGRVPFSVEFMPPRDDTAEQRLNRAAATFHDLGASFVSVTYGAG
GSTRARTQRVAEQLAQKPLTTLVHLTLVEHTEDELRDILKAYAHAGLSNLLALRGDPPGD
PLGEWTPVEGGLRYASELIELVRSIDECAHFDIGIASFPEGHYRASTLEEDTLHTVNKLR
AGANYSITQMFFDPEYYLRLRDRIAALDPVQGEKPIIPGLMPITSLRSVRRQVELSGAHL
PRELEERLEKAARGDEQANRDDIRKVGIEYSTAMAERLIAEGVPDLHFMTLNFARATQEV
LHNLGMAPAWDAAHGQDVLR
>A0A7X4A846|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTRDRRSVAYPAELQPLLQRLLTHMSTETLPDIDQVDKVCAHVPPGTRVFVASLPSRDRA
DTVAAAKILNDRGYVAVPHIAARALPSHAALEDFLYRLTGEAGCREALVIAGDRPDAAGP
FAETMDVLLTGALERHGLQTIHVGAHPEGNRLIGDDALREAMLSKAHYAGSSDADFDFVT
QFVFDGATVVDWAQRLRGLGIGLPVRLGIAGPADLATLLRYAKICGIGVSTRALMRQGAG
SVKLIRRTVRPDDLLAGLVAAAGTDPLPEIAGLHIFPFGGVGRAMAWLADAREAAGL
>A0A7Y9L2H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. E4BP6|TrEMBL
MKITEHIKNANGKTLFSFELIPPLKGHSIQGIYDAIDPLMEFKPPFIDVTSLREDFIYKE
HPNGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLVDLQFLGIEN
VLVLRGDARRGDASFVPTPNGHNYATDLLQQVVNMNNGVYLHEHTDENLKTDFCIGIAGY
PEKHFEAPNLKTDFKYLKQKVDMGANFIVTQMFFDNQKYFDFVNNCRANGINVPIIPGLK
PITGSKQLTGLAKTFHIDMPEDLSDAVHACKTEKDVKDVGIEWMINQCKQLMAFGVPVLH
FYTMSNPGPTKRIAEAIF
>A0A851TKC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothocercus nigrocapillus|TrEMBL
MVNENQHTCSTSSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDK
WFSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPAGEEWQEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAENYEADLRHLKEKVLAGADFIITQLFFQSETFLK
FMKDCQAIGITCPIVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWTEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGERNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYETRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7W9ICZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium becharense|TrEMBL
MALGRPSVLPDRVPTVRELLAAGARSFSFEFFPPKTDEGERQLWRAVRELEALHPTFVSV
TYGAGGSTRDRTVDIVERIAHETTLTPVAHFTAVNHSVRELRHLVGRFAGAGVRNILAVR
GDPPGDVTGEWVRHPEGVLYAEDLVRLIRQAGDFCVGVAAFPYKHPRSASVESDTEYFVR
KCRAGADYAITQMFFRADDYLRLRDRVAARGCDTPIIPGIMPVTQLSTIARSEQLSGAPF
PPEVAARFEAVADDPAAVRRLGIEHAAELCQTLLDEGAPGIHFITFNRSSATREVFQALD
PVPSAASLPA
>A0A8D4FZ08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus ruber|TrEMBL
MDRLRAPRGARIPFSVEFSPPRDADAEARLWRAVREFERLGPAFVSMTYGAGGSTRDRTV
RVTGQLAQETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWTR
HPQGLEYAEELVRLVRDLGDFHVGVASFPEAHHRSPDLEHDTRYLVHKLRAGAEYSITQM
FFDVEDYLRLRDRVVAYDPEQGAKPIIPEIMPITSLRTARRSLELSGSKLPATLEERLVR
AAGNGPEEDRAAVREVGIDVATEMAERLIAEGAPCLHFITLNFARATREVLARLGIAVPT
AV
>A0A7J7M5J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingdonia uniflora|TrEMBL
MKVINKIKEASTEDKVVFSFEFFPPKTEDGVDTMFDKMDRMVSHSPSFCDITWGAGGSTA
DLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSYGIQNVLALRGDPPHGHDK
FVKTEGGFACALDLVKHMREKYGDYFGITVAGYPEAHPDVIDSNGLVTLEGYQKDLDYLK
SKVDAGADVIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTR
IPAELTAALEPIKDNEEAVKQFGIHFGTEMCKKILAHGIKTLHLYTLNQDKTALAILQNL
GLINETKISRPLPWRPPTNVFRIKEDVRPIFWANRPKSYLSRTLGWDEYPHGRWGDSRNP
SYGALTEYQFLRPRSRDKKLNEEWAVQLKSVEDIHERFMKCCLGELRSNPWSELDGLQPE
TKIINELLGDINMKGFLTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYVEFFCSMDKLS
TLINKCKTFPYLTYMAVNKEGKRISNTGLSDVNAVTWGVFPAKEIIQPTIVDPASFMVWK
DEAFDIWTRGWGNMYPKGDSSRKLLEQVQSNYFLVSLVDNDYVNGDLFAIFNDV
>A0A0T8TZE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pseudopneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2E7DI38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTDQLHVSFEIFPPTDDSGEHALWKTVERLASLDPAFVSVTYGAGGTSRKRSTKILDQLV
RRTSHEAAAHVTCVGTTREEINALARGWSKKGVKRIIALRGDPPAARGTRFEPHPSGYSD
TVALIRGLLRVAEFEIAVGAYPETHPDATSPEADLDHLKRKLDEGAAFGITQYFFDAETY
LRFRDRAVAAGIDKPIVPGILPVTNFARVAEFSARCGATVPYWMRELFEGLDDDAETRRL
VAASTACELCNRLKTEGVTRFHIYTLNRAELSMAICRRLGMRPRLADAA
>A0A2E5V651|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTDNQLFPTSMAANLNVSFEFFPPKTDKMFDSLWASVKRLEPLQPQFVSVTYGAGGSTRE
RTHSTVVKILKDTNLVPAAHLTCVNSTRDQVDEVARAYWEEGVRKIVALRGDPPTGHENY
IPHPGGYDYAVDLVAGLKRIADFDISVAAYPEGHPQAQSRDFDLEILKQKMDAGADRAIT
QYFFGAEPFMRFMDRAGAAGINIPIIPGILPVQNFSQVIKFNQMSGTKTPAWMAEMFNGL
NDDAETRRIVAAAIAVEQCRQLYDYGIHDFHFYTLNRADLTYAICHILGLRPHKK
>A0A2D7TCU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MESKLRKLLKKDKFVFTAETSPPDSGNKDVIREQVKCLDGLADAVNVTDGAGAKSHMSAL
ATAAILAQNGIEPVLQFTTRDRNRIAIQGDLLGGWALDIPNILCLYGDEVKGGDQPDTKE
VRDLDTIGILKTAHEIKTKKMYPSGRKINDAPKFFIGGADTPFKVNDDFDGSGLIKKIEA
GVEFFQTQYVFDIDILETYMLKLKELNITDKAFFIIGLGVIKSSKSARWMNQNLFGINIP
EEIINRIEQSTNESLEGIKICIELIDKYKSIEGVSGIHLMGYXQEKEIASVISNFK
>A0A368YN91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus lutimaris|TrEMBL
MTIAVTTPAVSFEFFPPRNLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVT
ALASHYGLNVAAHLTCVDATREETLQIVADYAAAGVNEIVALRGDAPQGQERFTAHPDGF
ANSVELIEAIAARGDMTIRCGAYPEPHPDSADTAADVAWLKRKVDAGASSAITQFFFDPE
TYFRFRDSCVAAGINAPILPGILPIQSWAGTRRFAERCGTAVPQWAEDAFAAAGKEGEAQ
LALDVCVKLCERLVAEGVDRLHFYTLNKPELVLKVCAALGIAPKGDISQVA
>A0A494W1V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium amiense|TrEMBL
MTLNDPAAPLYADLAGDARVSFEFFPPKTEKMEAQLWSAIETLTPLAPQFVSVTYGAGGS
TRERTHATVARIAQETPLAAAAHLTCVAASKAEIAEIADAYWNAGVRHIVALRGDPPEAG
GRFEPHPDGYNGAAELVEGLVKLHPFEISVSAYPEVHPDAASAQSDLDNLKRKLDAGATR
AITQFFFSPEAYFRFMDKVLAGGITADIVPGIMPVSNFAATKRMAAMCNTAVPSWMARLF
EGLDDHPGSRQLVSATIAAELCRSLYEGGVRDFHFYTLNRAELSYAICHLLGLRPRAALA
SSEKAA
>A0A2E0GIH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MDNXXKNINKLSESLLQXKFVITAXTTPKTNTDLNASLEKXLCXKGLADAVNITDGAGAK
SXLSSLXLSGXMXSNGIXPIIQXTLXDRNRIAXQSDXIGAAAXXVXNXXVLTGDPAEVGD
EKXAKFVGDFDSSTGLISLLEKINNTGELNSGRKINNPPEIFLGAADAPFLPPSGWKPDK
LIAKIDSGAKFFQTQYCFDMKVCKKYFSILSDFGLLESVYFLVGIGPFSSSKQAKWMHEN
LPGVEVPDKILNILSKSKDEKKDGKKICLELLDELQEIDGVSGAHIMGPGQEQTVAEIIQ
AKRK
>A0A2E9Y0R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MMPPIHDSRVFSSNGMGPLSISFEFFPPKSDAMAEQLWRAMERLRPLGPAFVSVTYGAGG
STRQRTHDTVVRIQGEGNVPCAAHLTCVGASRDEVNGIAQDYWDEGIRHLVALRGDAPEG
QEYQLYPHGYANAAELVAGLRNIRDFEISVAAYPELHPNSPSSHADLDNLKRKIDAGATR
AITQFFFDADIYLRFLERARAAGIWVPIVPGILPVSNFVQAAQFAKACGATMPTWMAHLF
EGLEDDPETRRMVAVTTAAEQCRKLQTAGVMDFHFFTLNRAELTYAICHILGLRPQSSDL
EETPA
>A0A414B8B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum hallii|TrEMBL
MNTMQTNPQDILKTLSLSFEVFPPKKWEDFPGLYETLDELKGLHPEFISCTYGAGGSNSK
KTAEIVSHIENELGIRSIAHLTCAALTEDKLLSTIENFKNAGIHSVLALRGDKPFDMSEE
DFANRQYKHPSEIIPILKKAGFRVAAACYPEKHYEAPSTEEDLHWLKHKVEQGADALISQ
LFFDNDAFYRFMDAADQKGITVPVHAGIMPITSAKMINTTINLSGASIPKALSDLIATYG
ENPSDMRKAGIEYAARQINDLAEQGMHYVHIYTMNHSETAKEICGLIK
>A0A1U9MCD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bartonella apis|TrEMBL
MSAPSLSRRPDLGDKLKVSFEFFPPKTEKMEEMLWQTVKRLAPLKPEFVSVTYGAGGSTR
ERTGRTVERIIKETHLNAAAHLTCVDATREEVDGVARQFASMGIHHFVALRGDPSNGAGG
RYHPTPGGYANAVELVAGLKAINPDFEITVSAYPEKHPESPDFATDIDLLKRKIDNGATK
AITQCFFDNHFYEDYIERVRKAGIYIPILPGILPIHNFWQVKNFCARNGTHIPDWLAQRF
EGLEEDQKTHDLVAAAVAAEQVLDLVEHGVEDFHFYTLNRADLVYAICYLIGIRPKKETA
ELSTGD
>A0A2D6T574|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSNAAEVQDPASGFKSGSCLERVLAGGHFAVTGEIGPPKGWDPEVIRKKSELLLGYVDGA
NITDNQTAIVRMSSIAAGIIAKQQGLEPIIQMTCRDRNRLAMQSDLLGAAAHGINSVLCL
SGDHQSFGNHPGAKNVHDIDSLQLVQMVKGLREGRFQCGEEIKGGGPGYFVGAAANPFAD
PLDWRPYRLAKKAAAGADFIQTQLVFDVEHFREYMKKVVDLGVHERTAILAGVGPLKSTG
MAKYMRDRVPGMMVPDFCVKRMADAVAEVDPDDKKARAETWRAEGIKLCIEQIQEIREIE
GVAGVHIMAIEWEAAIKPLVEGAGLYPRPEVGDE
>A0A5L4VYW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter hyointestinalis|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHYLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A350YJY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSDRFIPSDISFSLEVFPPKTADGLDHLLAAVDAYVAIKPAAITVTFGAVGSDETTAHVR
SVIRRIRQHTDVPVIAHVTCAGRSCAEVDAFVDDLVQDGVAHFVALRGDMLGHGAPYHPH
PDGYAMTYDFVAALKRRHPAQQVYVAGYPEMHPESPSEAFDLDHLKRKVDAGADGVLTQF
FFDPEVFLHWRDKVEKRGVHVPLVPGLMPILDFKRTCAMAQRCNAQIPDFLHTMFDGVAP
ESIDHKLLAMNVLSHQITRLIEHGVSHFHFYTMNETILTRHLCTWLRTGF
>A0A558GIJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium aurimucosum|TrEMBL
MSPRLSASAPLDQISEDTPKELKRTALSFEVIPPRHDADAAKIDRLLAMLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTEEELVGWIDTLVDAGVRGLLALR
GDLPEGGMPEGHLPHADSLVRLIRRWESDRVARLAAGRLAVGVACYPNGHAESATPDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTKVLDQLAAATSPEEEKEIGMQITAKLAKSVMNAGADGLHIYTHNNPDITTDLL
HRIGVIP
>A0A5B2U3U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sediminis|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVDQINNLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>G8B6Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida parapsilosis (strain CDC 317 / ATCC MYA-4646)|TrEMBL
MKITEKLNQAHVGISNPPPATFSFEFFVPKTAQGVQNLYDRMDRMYDLNPIFIDITWNAG
GRSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALDKAYKSGCQNILALRGDPPL
DGSESTGDFKYAKDLVKYIRQKYGNHFNIGVAAYPEGQPEEEDESKTLQYLKEKCDEGAD
FIITQMFYDVDNFITWCGKLRKIGIDIPIIPGIMPISTYAAFIRRANWSQIKIPQHFLDA
LDPIKDDDYLVREKGTELVSEMCNKLIESGYVNHLHFYTMNLEKSTVMALEKLNLVEAIK
SHEVVGGAELPWRKSLHPERSKESIRPIFWQNRKYSYISRTATWDEFPNGRWGDSRSPAF
GDIDLCASELLRQSPKRALELWGVPQNLKQLSDLVVSYLSGELKSLPWSDGAVGEDTKII
VDDLINLNKRGLLTMNSQPALNSIKSSEKVFGWGPKNGYVYQKQYLEFICHRDIVDKLLT
RIQDFNKSQGDASSSIISYYAVDLSGKLQTNCKPDDINAVTWGVFPGEEILQPTIVEQTS
FLAWKDEVYRLFSEWNKVLSSNLVDIDDESKLSNFTRLMNEVGHEFVLCNLVNNDFIDSN
STLFSLIYDLNLPELP
>A0A831TZ28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter metallireducens|TrEMBL
MSATPPMPSTLREQLESNRFVVTAEVCPPKGCDCGEFMDKARSLKGLVDAVNVTDNQGAN
VRISPLAPAALLAREGIEPILQLTCRDRNRLALQSELLAAATLGVTSILALSGDYISFGD
HAGAKPVFDLDSVQLLQTIATLNSGRDISGAPLEGIPSFFAGAAAAPEAEPFDLTLPKLA
KKAAAGARFFQTQAVFSPERLARFSEAVRPLGVKVIAGIILLKSASMARYITNNIPGLKV
PPELVAELEAAERPLDTGVEIARRLAAAARPHCDGIHIMAMGREELVPDIVAGLRAENH
>M0KEQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula amylolytica JCM 13557|TrEMBL
MALGTRAVSDSQGVRTLLTSARFELMPFESFDEEITHLPDDATIAITTSPQLGIEKTVEK
TEEAADMGFDVVPHIAARYVEDRAQLEAIAERLEQAGITDIFVPGGDREEPAGEYESAHD
LLEALAETEYSFAEVGITGYPEGHDFIDDETLAESMAQKAPYATYIVTQLCYDPETVLEW
VEDIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDDEYNIRGVHIYTFNQTPDTEKWRHNRLDS
>A0A7X7NBP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MPTKQDDRQLNINFDLKPDIAQLLNKSTFFVQLELRPELDGTLSPLTIALAKAADNLFPG
DELSFNLNSLLEDGTTTTTTKSLAQLQAMTQRPVVMTLSGQGRSLYNIKTEAAEAKSVGI
SNVLVATGNLSPLHTPDKRGHYAPLTPGYVDSLDILSSLDTLQPNFTRGAVVNPYKYTPE
DQCLQYAKMVRKCHRGSEFLVAQAGWDMKKAQELQWFMQMRELVRPTLARLFLLTCEEAR
QLPNIDVPGLAFPLPVAAALQRHTDDEKNFEDYQFNLATLQAIGYKWLGYSGLQIRGIFQ
ADKLREFHRRLAELQKDITSYATWLERWNQFHGNISFAPTPTLHSTSRNHYLFTNLLDPQ
VLNYDEQICELAKSSIEQPPTLQVLKARLMKPSAKSLPAKIVKNMFKPGTEACYALHNDS
CPKRLTKSPCGNSKTDGFCEANHAPCFFKKVVEFSSALGEMNILEND
>A0A1G0XSJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_49_21|TrEMBL
MSESKSTIQMEIDFQKQKRENVFRERLNKGSFYVLIEAITPEKKEDFAIAANRLKAVESS
LGKYDIIGTGLAITDKTAGWNTWNVADFANELSKEGRDRHVLYLSGRNATIKDVSDTIAR
CRSSGFQNLVPVTGDGYFPEGYKRRHKLNFVDSVCILNMLKSVDEDGFHFAGCTMNPFKY
TPSDIFPQYYKMVKKMKQGAEFIVTQSGWDMMKLQELRWYLEMRELHFPSIARFSLLTIE
LYEEIFSGKKPGMIISAELRKILLNEAKYGYAQFASAQWRRLQIYAAGAKFLGYSGIQIS
GIERQEHIATACSKVAEAMNEFKSFEEWRDGYLNYLSRADMTPYPYRFYMFNNLFTRAYP
ELATMKSADLPVGGKFEKLHYSLCRLFFSKVHRHAANEHLLAKKIFVGCRRCSTCRIPFT
QFVCPETCPKGLANGPCGGTHIDGTCEFGGKQCIHAKIFRLSAWQKELHSLEERYIKPLE
KI
>A0A174Z5V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium innocuum|TrEMBL
MIENYLNTQGYMLFDGAFGTYYAQRYAEDQKPCEMANLNHPKRVAAIHQEYIEAGADAIK
TNTFSANEQHLECSWEMIRRILQEGYRIAKEAAKDKVKVFADIGPIMEQKNVSLAQQYQQ
IVDVFLAEGADCFLFETLLNTQELHAVTSYIKEQCPQACIIVSFAVTADGYSRQGIAMSR
LLQDCLADEHVDACGLNCVCGPMHMKRLLDSIDRTQKPILIMPNAGYPTILANRTYFRDS
STYFAKEMREIWQKGARLLGGCCGTTPVYIQKTREALQEHKIIQKVQQPAQETQRIPQED
HNPLRRKLQRKQPVIAVEFDPPANCEIERFMNHVEFLKEAGVDAVTIADCPIARARVDSS
LIACKLHRELGLDVIPHMTCRDRNINATKALLFGLQIEGIRNVLVVTGDPIPSEDRQEVK
GVFNFNSQILAGYIRDLNETMFTSPFMVFGALNLNAVNFEAELAKAKRKVTQGMEGFLTQ
PVHSRQALFNLKRARKELQAYILGGVLPIVSHRNAVYMNNEISGIEVDEEIVAMYEGTTR
KEAQKLAVDISCKTMDEMRPYIDGYYLITPFNRVEIIADMITYIHKQ
>A0A349A501|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophus sp.|TrEMBL
MNITEILNRQKISFSFEFFPPRDARGAQMLFATIADLTSLKPSYISVTYGAGGSTRTLTH
ELVRRIRKETSLTVVSHLTCVGSTREEIAKILDAYAADGIENVMALRGDPPAGQRDYAGE
AGGFAHADELVTFIRKRFPAFGIGVAGYPEGHAETPNRLKEMDYLKRKVDAGADFICTQL
FFDNRDFYDFAERCALAGIQVPIIAGIMPLTSRQGMLRMADLALGMRFPAGLLKAVSRAR
DDRFVENVGVQWATEQVRDLIDQGVRGIHFYTLNRSKSTLRIYEALGVSDSAQLVE
>A0A1D8JLN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella sp. LTGPAF-6F|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAKDYWDSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1D8A990|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium resinovorum|TrEMBL
MTASPRAAETPIFAGLPGDISVSFEFFPPKSEKMEEQLWDAITQLAPLDPAFVSVTYGAG
GSTRERTHATVSRIVKETALVPAAHLTCVAASKGEIDEVVDQYWEAGVRHIVALRGDPLP
ADGGRFVPHPEGYASAAQLVEGIRKRHDFEVSVAAYPEVHPEAVSAEADLDNLKRKIDAG
ATRAITQFFFSTDAYFRFMDKALAAGITVPILPGIMPVTSFAAIRRMSGNTEIPGWLETM
FDGLDDRPGPRALVAAVAAADLCKRLYEGGSRDFHFYTLNRAEQAYAICQLLGLRPVKEL
VA
>A0A368L1Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvibium lacunae|TrEMBL
MSSSTPIISFEFFPPKTAEGMAKLQAAQQQLSACQPKFFSVTFGAGGSTQDRTLETVLEI
QRSGAEAAPHLSCVGSSKANIRQILQAYKSHGIRHIVALRGDLPSGMGEIGEFRYANELV
EFIRAETGDWFNIEVAAYPEYHPQARSPQEDLQNFIRKVKAGANSAITQYFYNPDAYWHF
VDTMSRAGLHLPIYPGIMPITNFTQLARFSDTCGAELPRWVRLKLQAYGDDVASIRAFGQ
DVVLGLCRNLLEGGAPGLHFYTLNQAGPSLALCQQLNYPQ
>A0A7V3AD82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MGGRMSTLRETLLDPARFACGVELVTTRGTLATKKAARIHAMANSLADLECVDWLSITDN
AGGNPMLDPVALGQPLMKRGKELAIHLACKDYNRNGLEARAWLLANEGFRNILALSGDYP
LTGFRGRARPASDLDSVALLALLTAMNEGMVVAPPTETRPRPLRLPGTGFFLGAAVSNFK
LHEREVIPQLLKLDRKIAAGAHFIVSQIGYDSRKFHELMVWHRRRGNERVPLVGNVYLLN
ARVAAVFNQGKIPGVVVSDELRAECERRGQEADQGRSFFIELAAKQVAILKGLGYRAAYL
GNIEKADDARQIWEKSRSYGPDDWKQFAREIRYGRPKEFYLFAEDPRTGLADPERIDPAY
EASLRRRAKSKHVTLGYRFSRRVHAAAFTPGTKLFCLGRWLYGRAKDPDHGPWWLRPIER
ASKAVLFDCRHCGDCSLPDIA
>A0A1E4TR94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pachysolen tannophilus NRRL Y-2460|TrEMBL
MSATIKERVQELGKDDIFYSFEFFPPKTESGLRNLMARMGRMSVLNPLFVTVTWGAGGST
SRKTLELASTCQQELGFTTCMHLTCTNTDKSIIDNALQKAKEFGVRNILALRGDPPVGEE
YYSPDPNNDFCYAVDLIRYIRKNYGDYFCIGVAGYPEGHVEGSHDSEQDPAKDLPYLMEK
VSAGADFIITQLFYDVDKFVEFEQKVRLELEKINKQDTLIIPGLMPINNYQLFNRASKLS
HASIPTSISNRFDDCIKTDDDKVKEIGVEILDDIVKQIYRKTNGRIKGFHFYTLNLEKSI
AQIIDRSEILSKVIANDEFENAIDDECIDQASQFSSPSSAISTKPRRDSNSNKVITNDVN
NVFTEDPLTAASSNFQTPKKTIVQISSGEGVLGRDATWDDFPNGRFGDSRSPAFGEIDGY
GPSLKVPKSKYYEFLGYPTSLKDISKVFINFLTNKISSYPWSDNIGLNPESALIQEELIQ
LNERFRFTLASQPATDAAKSSDKIFGWGPRDGFVYQKAFVELFISKDYFQNVLKPKLDGN
KNVSYFYADSKNNFKSSLESSSKNAVTWGVFPDREIVQTTIIEDESFKAWNEEAFKIWTE
WQRLYPKQSASYKLIGDIIEGYYLISIIYHDYKDENGLWDLLIEDH
>A0A8H3FIM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Imshaugia aleurites|TrEMBL
MEKITDKIAALPNDANYFSLEFFPPKTQIGFSNLQTRLERMSSTLRPLFVNVTWGAGGST
SSRSLELAEICQRQLGLTTCLHLTCTNMKRKVIDEALEEAKALGVRNILALRGDPPREEE
YRLEDETDEGEDKDDSNEDFTWAIDLVRYIRRVHGDYFCIGVAGYPEGHADQSHPTDQDP
LHDLPYLIDKTKAGGDFIMTQLFYDVEAYTKYEKMLREHESGVFAQIPIIPGLMPLQSYE
ILMRTTKLAHAKVPPELLHRLQAVKGDDEAVKQVGVEAMHDVVESIRDVKAKGPRGFHFY
TLNLEKAVSSLLERCNLISPDPDDNIISAIDDVSILVNGDAAHHRALSSTSSSAAAQLTT
NSHRSSSPSRLISPNGNPFSREATWDDYPNGRFGDARSPAFNPPLTYSPTSLTVSPAQAL
SLWGTPTTTEEITHLFTSHLAGQNPEQLPWSESATLSPETALITSELTQLTQTKGYWTIA
SQPAVDGLPSTHSVHGWGPPGGFVFQKAFVEFFVPASTFTTTLQAYLDHLCNEGEISYYA
GNAAGAFRSSESSEAKHAVTWGSFAGKEIATATMVEEVSFRAWVEEAFGIWSEWARCVGE
AARRGRVEKARESRDFLRMTAKDVWLVNVIGHDFREGGRLWEVLMEA
>A0A3M1I1Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MSDRHAFLAALEEGVLLADGAMGTMLHARGVDFDQCFDELNLTNPALVADVHREYIEAGA
QVILTNTFGANRYKLSRHGLEDRVAEINRAGVELARRVVAASFREVFVAGDVGPLGVRIA
PFGRVQPEQARKAFAEQITALCEAGADLIVIETMSDLYEIQEAVRAARQVCSLPVVASVT
FTRDDRTLLGDSPVRVARVLRESGADVIGVNCSGGPAQLLRILKQMRQAAPEAIFWVKPN
AGWPEQVGGRIMYPADPDYFGEYALSFRRAGASVVGGCCGTTPRHIAAMRRALDQAPDLS
IAPAVLSPLEEEALEPAEQPTQLAQKLAAGRFVIAVEMDPPRGLSTHKLVAGASLLADSG
ADVIDVADTPMARMRMSAWAVCDVIQRQVGIETTLHFPTRGRNLLRVQGDLLAAHALGVR
NVFVVMGDPTSIGDYPEAMDDYDLVPSGLIKLIKQGFNVGVDHSGTSIGQPTNFFVGAAL
NLSARDPQREYRNLRRKLRAGADFFLTQPVYEPEAARAFLQRYEEEYGPIERPILVGILP
LVSVRHVNFLHHEVPGVFIPEAMRDRIERAGERGAQEGVRVAVELIEQLKEWAAGVYIMP
QFHRYDLVAEIIEAVR
>B3QGP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas palustris (strain TIE-1)|TrEMBL
MSDLPQQLPAISFEFFPPKTEEMERNLWQAISRLAPLHPSFVSVTYGAGGSTRERTHATI
ARILKETDLTPAAHLTCVDAPCADVDDVVARYHDIGVRHIVALRGDPTTGLGGTYTPHPQ
GYRSSADLVASIKRRYPDIDVTVSAYPEKHPESTGFDADLDILKAKVDAGATRAITQFFF
DNDLYFRYLDRVRARGINIPIVPGILPVQNFKQAAGFAARAGASVPDWLAKQFEGLDDDP
DTRKLVAATVAAGQVHKLAKHGVSNFHFYTMNRADLAFAISHLLGFRPIAKQKAA
>A0A832H8Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MLVKDILAGARTAFSFEFFPPKAEPEWEVLFQQIAELRALEPSYVSVTYGAGGSTRDRTH
DLVVRIQRETGITVVSHLTCVNSGREEIAAILDRYDAAGVHNILALRGDPPKGQPWASAP
DGFPYAADLVAFIKRRHPHFGVAVAGFPEGHPGTPNRLQEMDYLKAKVEAGADYIVTQLF
FDNRDFFDFCERCQLAGIHVPVVAGIMPVTTRSGMVRMAAMAAGARIPAGLLRAVSRARD
DAEVARIGVHWATEQVRGLIDGGVRGIHFYTLNKSAATRRIYENLALHGAIVG
>A0A7X1IMB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TYQ1024|TrEMBL
MALGTASTRTDHARTVRDLLASGERSYSFEFAAPRTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSVAELRNVIGQYADVGIRNMLALR
GDPPGDPTGEWVRHPQGLHYAVELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFHADDYLRLRDRVHAAGCETPIIPEIMPLTNVRQIERFAQLSNAAF
PADLAERIRAVEDDPAAVRSIGIEYATELCARLMAEETPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A7V3NCH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSGEAFRNALAEGVLIFDGAMGTEIYRHHVFTNRCFDELSLSDPKLIRGIHQQYCQAGAD
VLTTNTFGANRVALGRFGLAERLADINRAGARVARSVADEAGRPVFVAGSVGPLPQQLQF
EDQIESMLIEQIEALLEGGVDFILFETQPSRKAIEQCARAMRRHPEVPYVLSFAIVDHGE
TASGESVERMLAPLPEECPPPAAWGMNCGTGPDGLLGPVEAAARRVRHLIVQPNAGLPKE
VENRRIYYCSPEYLAEYAKRYVSLGAVGVGGCCGTTPDHIREVAKAVKPLHKARVQKVLL
EPAPAVEEKPEVPFAERSRLAWKLAHRQWVTTVELVPPRGYDLSDTIAKSKLLHRHGVDA
INVPDGPRASSRISPLVTAYRIQQEAQIEAILHFCCRDRNLIGMQADLLACAACEIRNIL
FITGDPPKLGNYPAATGVFDTDSIGMVAVQRRLNRGIDLGGQPIDPPTAAAIGVGLDPTA
LDQDREVDRFRQKVEAGAEFAITQPVFDPEALLRFLDRVQQYAIPIVAGVWPLVSYRNAS
FMKNEVPGVVIPDSVMERMAAATSRDDQLKVGIDIARESVQRIRDRVAGIQVSAPLGKVA
IALAVIE
>A0A7Y3ULF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MDTQNNNNFKAGSNLEKLLRRGEFVVTAELGPPRGASRDAVEEKAKLLTGCADAYNLTDC
QTAMVRLSSIASGVMLLNMGMEPIIQMTCRDRNRIAMQSDILGAAALGMKNILCLTGDHQ
CFGDHPEAKGVFDIDSIQQLNMFREMRDEGKFQSGDELKVAPRLFLGSAANPFADPFKYR
APRLAKKIKAGSDFIQTQIIYNVKKFEEWMGHVRDMGLHKKVSILAGITPIKSLGMAKYM
KKNVPGLDVPDEIIQRLEGVKSKKAEGINICLETIERVRKIEGVAGVHLMAIEWEETIPE
IVERAGLLPRPTL
>A0A7V9GL21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTEHIKESKGSLVSFEILPPLKGKGIDAIYNHLNPLMEYKPAFINVTYHRSESMFKKK
PDGTFEKVDVRKRPGTVGICAAIKSYYQVDTVAHLICGGFSRQETEDALIDLNFLGIDNV
LVLRGDAPKNESTFEPEPGGNRYAIDLLNQVMDMNHGIYLEEDLKNVVKTDFCIGVAGYP
EKHFECPNMATDILHLKEKVDAGAEYITTQMFFDNACYFEFVKLCRNAGITVPIIPGLKP
ITSKKQMTIIPRTFHVDIPTELSNEVLKCKNDEDVEKVGTEWLIEQSRNLQQKGVPGLHY
YTLGKPHVICNTMKAIL
>A0A7C5KRK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MAKNKLISTLKVAGAATGLAIAAAYAARKIFVPTRRYQAPFSPARRDDLTLPLKAFTAFE
KGIKGMFFDCRMCGNCILQETAFVCPMTCPKGLRNGLCGGATPEACEVDPSRPCTWYIIY
DRSEKMGREHKLLEINAPIDGTKAGHETWLDTIKTWQKKAYKPNPVDFFVDRKKFNKDWE
DLFYEIRQPDWWQGDAEYPPPAYQEPISLLEANLRTGAFVTTAEIAPPLGASGNIIHKKA
GWLKNYVSAANFTDNASASARMSSVASSKICLEDGLEPVMQLQARDRSRVVIESDVMGAA
GLGIRNILCLSGDHQRFGPGPVSKPDQFDMDAVQIIWMLRRMRDEGVYLDGRKIKRRPEL
FLGAAGSPFGAPPKYEALRAHKKINAGAQFIQTQPVFDYNRFLEWLEALDRRNLLDKVYI
LAGLIPLKSARAAHFMANDVPGVYIPPAIVQRMDNAGNKEGQQEEGVTIALEMIEKLKNT
PGLNGMHIMAVHWEAIVPRLIDKSGVPKPAFTNPSQINSAAPSEAIP
>A0A892ID45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia dolosa|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAAYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCRRLLDAGVPGLHFYTLNAAAATRTICERLDV
>A0A7C3GWG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
VPRLVQYMQRVRDLGLDKKVFFLVGVGPLKGPKSAEFMRSKIPGVHIPDAIIKRLKGVTG
KKARNAEGKKICVEIIQQVREIVGVDGVHIMAYRQEEVVGELLDEAGLLPRPFKLHKPKI
NPDTFAPPAIAASFESYTKKLVGQ
>A0A7C7QQH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
KGVEPRFFIGAAANPFADPFDYRPHRLAKKIAAGADFIQTQIVFNVPKFRQYVKRCGDMG
LLDEVYLLAGVSPIRTLGAARYMANFVPGMDVPQEYVDRMKGAVAGIPKEDKARRREAWE
REGIQICVEVIQQVREIPGVAGVHIMAIEWEEAVAEITKQAGLQPRPTVD
>A0A7C2Q1M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrososphaeria archaeon|TrEMBL
MSGCPKRVLNGPCGGMRPDGTCELGDRRCVFSERYPSKIILDHGFKFRPEIRRRQSFTKL
LTEVERRPVWVAEIPPSAKVLSNIDLLRGLSFTALSIPDNPLALPHVENSVFSQLLRERL
GCEVIVHLTCRDLSRLAIKSRILALALCGVEHILALTGDHPRMVSEEYAPVFDLDSIRLI
CLARIMSDYGVDELGDKLQVMPRIHVGAGLNPYIPLEIEVSRVLRKHEAGAEFLVTQIIF
DAEPIEKILKALKNAGIIIPVFTGFLVEEEPIIRRVIKIMGLPEADIPRDPEKLVDKYIE
TFRRLRRTYGPVGVFISTLGKIRNLKLWDQAFRSCLAKE
>A0A257N6K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium NSM2-1|TrEMBL
MQSQKKHPQLFSFEFYPPKTEEGVANLQIVHSKLAKLNPDFFSVTFGAGGSTRDLTFDTV
VAIQAKGIAAAPHLSCVASTKDNIRAILKDYQDNGIAKIVALRGDLPSGMMSAGEFRYAN
ELVEFIRQETGDYFQIHVAAYPEVHPQSASGIEDFKNFKRKVEAGANAAITQYFYNAEAY
FYFRDSCEKNGIDIPVVPGIMPITQYTQLFRFSEMCGADIPRWMRKRLEGFGDDRASIQA
FGLDLVTNLCQRLLDSGAPGLHFYTMNQAAPTLAILENLQIKAQD
>A0A3B8PZD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MWLVIRLIHDVHVALAKADRPSISVEFFPPKTDDGERNLFTNTLPELVKVNPAYCSVTYG
AGGGTRDKTLGIVDRIQREFDLTTMMHLTCVNATRAQLREVVEEARGKGIRNILALRGDP
PGGGPWTKTEGGFEYSRELVSFIRELGGFNIGTAGFPEGHLAQAAGKFVAWGFLAEKVRA
GADFVITQLFFDNADYFAFRDHLVSRLGVTVPLIPGLMPVLSRNQTKKFTQMCGAKLPAP
FLQRLEELGDDDAAVTEFGIEYCSRQVEELLREGAPGVHFYTLNKAHSTVRVMRNLSLA
>A0A2D5ALH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHVQDIFAKRSPTFSFEFFPPKTEESSQALYETISELESHEPDFVSVTYGAGGSTRELTN
DLVVRIKNSTSLDPIPHLTCVCHRESDIEAILARYAEEGVTNILALGGDPPRNLENYSKA
DDAFQQAADLVRFIKKFSEAGNHPDARGFGIGVAGFPEGHPATPNRLKEMDYLKAKVDEG
ADYIVTQLFFTNDDFHDFRDRCELAGIHIPIIAGIMPVTSTKGMERMADLAAGARFPAKL
LSAIYRANDTETVEKVGIDYATEQCSDLLANQVNGIHFYTLNKSHATREIYASLGITPST
SLNL
>A0A2D4ZBV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHIRDIINKEQPSFSFEFFPPRSDEASTELLKTIKELEYLNPSYVSITYGAGGTTRERTH
DLVEKILDSTCLIPIPHLTCVQHNEEEISTILKRYINKGISNILALRGDLPEDNNNYDRS
QDSFQYASDLVQFIKSYCKEQPDKNSELLGVGVAGFPEGHPNTPNRLKEMDYLKAKVDSG
ADYICTQLFFDNHDFFDFKERCLLAGINIPIIAGIMPVSSMKGLQRMANLAAGSRFPAKL
LKSINRCNSNAEAIEKVGIQYATEQCADLLNNDVEGIHFYTLNKSKATRGIFESLGINKI
SI
>A0A3D5JV55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDIHAEKAAAGKPTISFEFFPFKTTEGEAAFFGKTLPALLTARPDYASVTYGAGGS
TREKTLEIVEQIQNDFSLATMAHLTCIKHTQAEIDAILDEANNRGIRNILALRGDPPPGE
DWSQTEGGFEFASELVTHISNRGDFGVAVAGFPEGHIACGEGREVDWQHLVRKVGCGGDM
VITQMFFDNADYFQLADFLRGAGVEAPLFPGIIPVANAGQIKKFSAMCGAKLPEAFAARL
DELGVDAEAVREYGIEYATAQCRELLDRGAPGLHFYTLNKSEAVLQILGNLGLA
>A0A2U2SHS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MAPNGYVSGSNLERVLKSGNFAVTAELGPPQSADAEVIRKKAALLRGFCDAVNITDNQTA
IVRMSSIGAGALLVREGLEPVIQMTCRDRNRLAIQSDLLGAYALGMRNVLCLTGDHQTFG
NHPQAKNVFDIDSIQLVQIVKNLRDQHIFQCGDPLKGLEPRFFIGAAESPFAHPIEFRPY
RLGKKIKAGANFIQTQLVFDIPAFEAFMEKVRALGLHQQAYLLAGVGPLKSPAMAKYMKE
NVPGILIPQELIDRLEEAGRPWAGKSRDELTKEEKKARSEAWKQTGIEICIELIQKILKI
EGVAGVHIMAIEWEEAVEPIVKGAGLYPRPVIEPLPV
>A0A102D7S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. Fuku2-ISO-50|TrEMBL
MIETLMIDAPLFAEMTGDVRVSFEFFPPKSEAMEAQLWDAIGALAPLDPAFVSVTYGAGG
STRERTHATVARLVRETALVPAAHLTCVGASRGEIDEIADRYWEAGVRHIVALRGDPPPE
SGGRFTPHPDGYANAADLVAGLAARHGFELSVAAYPELHPESPSVEADLDNLKRKIDAGA
SRAITQFFFSAETYFRFLDRVLAAGISVPVLPGIMPVTNLAGIRRMGGNTQIPDWLEAMF
AGLDNRPGPRALVAAVVAADLCRRLYEGGVRDFHFYTLNRADQAYAICQLLGLRPKDTRS
>A0A3M2CNM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MHIEDIFSRRRTTFSFEFFPPKTEKGSESLFAAIRDLEPLRPAWVSVTYGAGGSTRDLTR
RLVLRIMRETSLEVMPHLTCVAHTEAEIYDLIERYASERVSNILALAGDPPESMPGYDRS
RDAFRHAADLVRFLREFRTRRGGRAIGDPRGFGIGVAGFPEGHPATPNRLTELEHLRAKV
DAGADFIVTQLFFDNRDFYDFRERCELAGIAVPIVAGIMPITSERNLKRMAELALGARFP
ARLLRALGRAGGDPDAVRRVGVHWATEQCRDLLDHGVRGIHFYTLNSSTATREIYANLGV
KDSLALA
>A0A415Z4R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. AM05-23|TrEMBL
MTIPEIMKNRMSFSFEVFPPKEEQPLEPLLDTLDHLYAFKPDFISCTYGAGGTNAGRNVE
ICKAIKDSGATIPITHFTCIGNSKDKIRDELRNYLSLGVDHILALRGDFPKGSASTGGDF
DYANELIAFIKEAFPEFSIAMAGDPEKHFEASSFDEDIAHLRIKQDAGADFIMTQLCHDV
AHYEWWVEKIRKAHITLPIDVGIMPVLAKDPTIRMAVSNGSSIPRDLAEIIARYGDNPKD
FKKAGVEYTVKQIHRFISAGIDGLHIYSLNKWADISEIVRAAGIR
>A0A2A4ZNV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MEWEAAGSTILEVVPPTLDSGLEGLYSRISRVRRLVSDGDFDAVNIPEIHDEENRNDQGI
RTRQYSPRMQPRELGRRIQDELGLPVIINHVVSFKPIGALMDWIRETVAGYGIRNIVLVG
APHERKPWPGPPVXEXNAAIRTEFXKEXXKIGNICIPGREGSPIPESVRMEEKAXSGADF
FTTQIXYDPTELIELRHQMVREASPARYCPILVSLCPVRRXRNLAFLRYLGVKIPDALEQ
ELXALGEPECLERSLEILRSIQSDLIEAQGDPADVAPLGWNIAPVGQIPTASIRDLMARL
SGSVRS
>A0A2E1ICX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MFPGIIPVANAGQIKKFSAMCGAKLPEAFVARLDELGDDAEAVREYGIEYATVQCRELLD
RGAPGLHFYTLNKSKAVLQILGNLGLA
>A0A117V406|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. Fuku2-ISO-50|TrEMBL
MAIVQIHPNWDKPPAILTHGYSLEMTAKDKPSLQDAAPLIPAETPIAVTFLPGEDAAARV
AATVAVRELGFEPMPHFSARRITSEDDFEGYLHAVVREAGVRRCFVVAGDPPEPQGPYFD
TMALIATGAFERAGIKAIGIGGHPEGHPEMTVEQCWDVLTRKVAEIEARGMAPLVVTQFG
FDPDAFLEWLAELRRRGIDAPVRLGVPGPAGIKRLLSFAARCGVGASASVLRKYGISVAN
LLGSAGPDKLVDAFAAGIGPQHGRVRLHFYPFGGLRKTVEWIADYERRQGQA
>A0A1F9CNI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_58_17|TrEMBL
EKVLEQGGFVVTSECGPPRGADPEVVRRKGELLRGVVDGVNVTDNQTSVVRMSSLSACAI
LKGMGLEPILQMVCRDRNRIALQSDLLGAAALGINNVLCLSGDHQKFGDHPQGKNVYDID
SVQLIQTVARLRDEGKFLGGDEVKGRPMLFVGAAANPFADPFEIRAARLGKKVKAGCEFI
QTQCIYNVERFTRWMEMVCERGLHERCGILAGVTPFKTAGMANYMKKNVPGMDVPDDMIA
RMKGVAKEKQAEEGIKICVETIERLREIPGVRGIHIMAIEWEEKVAEIVKAAGLLPRPEI
Q
>A0A356F988|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRFSEIYSAEDSPVISFEVFPPKSGRGMESLREVLPSLVALGPRFMTVTYGAMGTTRIRT
VEIASMIHNEFELECACHLTCVGAHSDQIDAQLDHIHRHGIENIVALRGDPPRGQDSFQA
VKGGFSYANELVEHIRSRGGFDIAVGGYPEKHVEAPDMETDLSNLARKVESGADVVITQL
FYDNECFFRFLEEVRKRGITCPVIPGLLPIHSQAQVEKIAGLCGAEIPAELQRRLEAAGT
DPDAAAEVGVDWCIEQCSGLLEAGVEGIHYYVLNKARVMEKVMAGLRARKLLI
>A0A3R9DGF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. FDAARGOS_558|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLDKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A5C8BS87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicycliphilus sp|TrEMBL
MNPTPSRIPVSVEFFPPKTPEGVEKLRGVRQQLYALKPEFCSVTFGAGGSTQEGTFKAVA
DILAEGVSAASHFSCIGATRATVRAQLATLKSMGVKRLVALRGDLPSGYGMGGEFHYASE
LVAFIRQETGDDFHIEVAAYPEVHPQAKSPQSDLEAFATKVRAGANSAITQYFYNPDAYF
RFVDDVAALGVHVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASIKAF
GLDVVAGLCEQLRAGGAPTLHFYTMNQSVATVALCERLGMVARA
>A0A6I5KRK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda sediminis|TrEMBL
MKITDHIRNAKGETLFSFEIVPPVKGKSIQELYNNIDPLMEFKPPFIDVTTSREEYIYKE
KDGLLDKKLTRTRPGTLGICASLKHKYDVDTVPHVLCGGFTKEETEYLLVDCQYLEIENV
MALRGDARKEEKYFIPTQGGHQYAAELVKQIHDINQGNYLHEVIEGHEMGDFCIGVAGYP
EKHMEAPSLQSDLKRLKEKVELGADYVVTQMFFDNKKFFAFVEAAREMDIYVPIIPGIKP
IAVKQHLQLLPQVFRVDIPQELIEAVEACKTNQDVRKVGVEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKDIAKELF
>A0A8J6N6F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfaltia bathyphila|TrEMBL
MNSNPNEKNRFKESLLNKNLFAITYELVPGRGSRSKVQDNLLAFAEKAAFGGKIQALSIT
ENAGGHPALSPGVLGKEILKLGIDPLVHLTCKDRNRNQLESRLFAQGREKMHNLLVMGGD
YPRYGFKGFAKPVFDLDTVQLIAMVDEMTRGFEVEKDAPGGGAKLPPIPFFKGCVISPFK
KLEAELMTQYFKLYKKIAAGANFVITQVGFDARKFDEALRYMRQNGLGVPILGNVYIPSM
TVTSVMHQGSVPGCVVTDKLMSMYKEEARLPDRGKKNQLIRSAKLLAILRGLGFDGVHIG
GSQLTYEDIDFVLEKGEEFYPDWQQWTREFSFPQEGGFYYYELDRKTGLNTDAPINRHQS
IPQKSAGYRFNRQVHKTVFDEKGWLYRPTRAICRKISGTFLEKLFTRFEYLIKFIGFECR
MCGDCTLSETAFLCPQSQCAKYLLNGPCGGSRNGWCEVYPGVKQCIYVRAYERLKSFGEE
ESLKKNIVPPRDWSLNRKSSWINYFMGKGHEALKRYL
>A0A330LQP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moritella yayanosii|TrEMBL
MSFHNAQNIEVLNQSVSELGRDINVSFEFFPPNSPAMTSTLWESINRLKALNPKFVSVTY
GANSGTRDRTHDIIKQIKNETGLIAAPHLTCIDANRQELKQIATDYWDNGIRNIVALRGD
LPPGLNQPDMYAADLVALLKEVNDFDISVAAYPEVHPEAKNAQADLLALKDKIDAGADRA
ISQFFFDTESFLRFRDRCAAVGIDKEIVPGILPVSNYKTLCKFSKLTNVKVPNWMHSQFE
GLDNDQATRNLVGASIAIDQVKILSREGVKDFHFYTLNRADLTYAICHTLGVRPR
>A0A1G1FX18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium GWC2_56_14|TrEMBL
MKSGSTLEKVLASGKPAVTAELGPPMSADPHEVIKKAQQLKGFCDAANITDCQTAVVRIS
SIAAAAIALQQGLEPVMQMTCRDRNRIAMQADLLGAAALGLKNCLCLAGDHQKFSAAGRL
KGHPGAKNVYDVDTCQLVGIMKKMRDESKQDGGDPIEVPPKFFIGASWTPMADPIDFRPI
NLMKKVNAGADFIQTQGIYDIEGFRTQMAKIVNMGLHEKTAILGGIIVPKSAMMLKYMDS
SVAGVSVPKSL
>A0A3A6C0N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AF15-14LB|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIREVAKQIY
>D6KPH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. 6_1_27|TrEMBL
MMTLREKHQQGQFTITVELDPPKSSSAEKTFEQAARLKGKVDAINIADSPMSKMRMSPIS
LSYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQS
VFEVDCMGLLNIAKTLNAGKDLAGNDLDAPTNFYIGATGNPGAPDLEIERQKLAAKIQNG
AHFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILD
RMEKGGKEAGTEIAIETLEQIKKMAAGVHIMPLNDIDTTLYIIDHL
>A0A0B4IH70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium majus (strain ARSEF 297)|TrEMBL
MHIKDMLAEAEKSGQPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLEKVNAALQKAYKAGCTNILALRGDPPRAQEK
WTAAEGGFHYARDLVKHIRATYGDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGKVRERGINIPILPGIMPIATYASFLRRAKHMQCKVPDHWMTAL
EPVKNDDVAVREIGKTLVAEMCRKLLANGIYHLHFYTMNLAQATRMLLEELTWAPCAERP
LQQALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTTVQDIASIFVKYLNREIESLPWSEAPLTGEANAIKDNLIQ
LNKRGLLTINSQPAVDGVKSSHPIHGWGPSNGYVYQKAYLELLVPASIFTEMVKRVEDKP
TLTYYAVTKDGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGTDW
AHCFESETPSRVLLDQIMNEWYLVNVVNNDFHENQTIFDLFEGLEVKGLDTPVAV
>A0A0L0WBY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gottschalkia purinilytica|TrEMBL
MLQEYLKENILITDGAMGTYYSEITGDKVSFCEFANINKPQVIRDIHVDYIKSGAKLIRT
NTFSANTISLGVTREKVKEIIEKGYTIAKKATEGTDVFIGASIGPIHESRFKKEDDIDIL
DEYKFIIDTFMELGENIFVFETFGTIDYLKEISEYIKSKNSDAFILTQFAVTLDGFTRKG
ISIKSIIDELKLIKSIDAYGFNCGSGPTHLYRLLKNMDIFSDTISALPNAGYPEIINERM
VYVNNPEYFGDIVVDISKLGAKIIGGCCGTTPNHIKSLVERLKIKTTDENIHVETKRTKL
ISENKKENNFVDKIEKQDFIIAVELDPPFDTSIERMIENARTCKEHGVDIVTIADSPRAI
ARVDSIMIAAKIKREVGIDVMPHVCCRDKNLNALKSGLLAAHIEDIRNMLVITGDPILDI
DKISTKSVFNLNSYRLIELISEMNKEIFKSDKINISGAVNLNVPNKEAEINRMLKKVDKG
ANTFFTQPIFSDETVEFLAKTREKYKVKILGGIMPIVTYKNAQFLNNEVPGIHIPEEYVN
RFHKNMTREEGEKVGIEIAIEIANKIKQHVDGLYFITPFDRIEMIVEILNRINYK
>H0Q4Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azoarcus sp. KH32C|TrEMBL
MIFEDEPVPGYPLPILPGHTSPGRLERVLRAGSFAVTTELEPPDSADPEEVYRRARVFDG
YVDAINATDGSGANCHMSSVAVCALLTRIGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NVMCLSGDGVQSGDHPQAKPVFDLDCMSLLEIGRKMRDEHQFQSGRKLAYAPRVFLGAAE
NPFVQPYEWRPHRLAKKVAAGAQFIQTQYCYDVPRLRVFMRHARDLGLLDKVFVLVGVGP
LRSAKAAEWMRTNVPGIHIPDSVIKRMAGAENQAQEGRRLCVDLIQEIREIEGVSGVHLM
AYRQEESVPEIIERSGVLAGRTPWYPDRDRKLQLHRTAS
>A0A7C1ANY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
PILNFRQVAKFAALCGTHMPSRIAARYEGLDDDPETRKLVAATIAAEQASDLAAQGVTDF
HFYTLNRADLVFAICHLLGLRPKAPAEKESEASQ
>A0A7M4D9W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labilibaculum euxinus|TrEMBL
MKVIELLNQAIENKTTHFSFELLPPLRGNSIYKVFNTIDKLKEFDPKYINITAHRDEVVF
TESESGLIEKKITRKRPGTVAVAAAIKNEYKITVVPHVICSGFTPEETENALLDLNFLGI
YDLLLLRGDSSSRHAFISSEGEHKYAIDLINQVNEINKGGFLDGTHVEPFATPFSFGTAG
YPEKHEEAPNIDSDIYWLKKKVDAGAEYIVTQMFFDNQKFFDFVKKVRDAGITVPVVPGI
KPISALSQLTVLPQIFKTDIPEALAAEVRKCKTNDEVKQVGIEWGIQQGKELIQHGVPSL
HFYTLMASDCVKEIAKAIY
>A0A7L1MKE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bombycilla garrulus|TrEMBL
MVNETQHSCSGSSSSRSDGGSSSGSEGSKDSSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPTGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7V1ANX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MTSRNERIKKFREILKERAMVADGAMGTALYGRGIPFSRSFEELNLSNPELVKDIHRGYA
SAGAELHETNTFGANRIRLAPHGLDRLVSEINRAGVKIAREAVGGEKWLLGSVGPLGKIL
KPVGKIDPEEAREIFREQIAALVEGGVDLIILETFTDLREITQALLAAKDVDDVPVIAQM
TFTEEGKSLMGDKPAEVVRKLRELGAEIVGANCSVGPQGIYEIMEIMAQADAGYLSAMPN
AGMPKMIEGWYMYLSSPEYMAQYARRTVEIGVNIIGGCCGTTPEHIRQIREMVWGKKPGE
RTKKGTSHFQFIESTEITAPPEEEKSVRESNFAVNLGKKFLVSVEIDPPRGVDPEKFIQG
ALYLKGKGVDAINVADSPLARARMSPLVLSHLISEETGIETIMHLSCRDRNILGLQAELM
GAQALGIRNILAITGDPPKLGDHPTATGVFDIDSVGLVTLIRNLNNGVDLMGRPIKSRTG
FSIGVGVNPTAIDLDYEMNKFARKVEAGAQFAFTQPLFDLKILEDFLKRAEKFEIPIFVG
ILPLRNFKHAEFMHNEIPEMFVPEHIRKMMFDAGENGPEVGVQIAQKFLLNAKDRVDGVY
LMPPFNKFEMAGAVLKVLE
>V9G656|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. JCM 10914|TrEMBL
MKPNLRQILGNEVLVGDGAMGTYLYQKGFPVGISYEELNLTSPEVVGNVHRQYIEAGARL
LETNTFSANFDKLSKYGLESKVEEINRAGVRIARAAAGEQGYIVGAVGSIRAGRRSNIST
NELKRYFEEQITVLLSEGVDGILLETFYDVEEIQLALAQVRKYSDLPVICQFAVEDVART
LDGFTMPDAYRILDQEGADVIGFNCRTGPNGIMRALETLNGVMNLPASVYPNAGIADYVD
GEYRYGASPKYFGETALAFAERGARIIGGCCGTTPEHIAEISAALAGFIPSALPVIEPEE
ARRIVIQERVHDDPHHSASGSEPTLVDTVKERHTVIVELDPPRDLDIRKFMKGAEALKKA
GADALTLADNSLAVTRMSNMALGHLVQARTGLRPLIHIACRDRNIIGTQSHMMGFDALGI
DHVLAVTGDPAKFGDLPGSSSVYDMTSFEIIRMIKQLNEGIAFSGKPLKQKAKFVVGAAF
NPNVRHLDKAVGRLEKKIASGADYIMTQPVYDPELIVKLKAATKHLDIPIFIGIMPLASG
RNAEYLHNEVPGIQLSDEVRSRMAGLEGEVGRAEGVKIGKELLDVATEHFNGIYIMTPFM
FYEMSVQLMEYVWEKSGRRSTPLFH
>A0A350ILE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MHKGKEFIQKVSNQVLLFDGGMGTELYNRGVFINQSFEELNLKNPSLVKAVHSEYRKAGA
DVLETNTFGANRFKLGKFQLADQVYEINLQASKLACEVAGEDLFVAGSVGPLGVQIEPLG
PISNDEARDFFKEQIRGLVDGGADLLIFETFIYPNELEQAVRAAREICDLPIIAQMTIDE
DASSLTGTSPAIMVDELNKIGADIIGVNCTVGPQVMLNWLEQVRKHTNLPISIMPNAGKP
RNIDGRNIYLSTPEYFGEYAKHFIKSGANIIGGCCGTGPEHIQKMRASINAQSPHFSTKK
YEIKNISVKEQIPIIPIAKKSRLAKRLSDGHFVKIVELLAPKGVSAENEIQKARELYYGG
IDAINIPDGPRASSRMSSLALATMIQNQVGIEVVLHFVCRDLNVIAIQSNLLGAYSLGIK
NVLAITGDPPKIGNYPDATGVFDVDSIGLINIINRLNNGLDISGAPIGNPTGFHIGCGAN
PGALNLDQELKRIDWKIEAGAEFIMTQPVFDLHIFENFFKRIEHYKIPIIAGIWPLTSLR
NAEFMNNEVPGCNVPNEILEQFRKVETSKDKSRILGIEIANKTLSSLMGAIQGVQISVPF
GNIQSAFNVLDGIH
>A0A3C0ZL81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MVKVDFRERIRQGPILCDGAMGTLLDLYEYEEQPHEIQNLKNPDIVERIHREYAEAGAEI
IETNTFSANRFRLTQFHLEEKLEEINRRAVEIARRAAGEKVYVAGAVGPTGKLLEPIGKL
RFQDARAAFREQIEILVKEGVDLLILETFVSLQELDEAISAAKEVSDLPIVAQKAFPEDG
SILSGTFPIEVVEHILSRGVDVVGANCTVGPQRMFSLIRSMYKDGVILSAQPAAGIPTLL
NGRAVYHTTPEYLGAYAKELVQAGVTLVGACCGSTPAHIRQIRKALDELQGKREEERGRS
EIVPRIVIKQAEIKVVELGKEKESERKDEWSLFAKNIRKKFLTSVELDIPRGIEMSAVLE
GAGYLHKHGVDAINITDGARARLRMSSVALSHMVQQSVGIEAMTHLATRDRNMIGLQAEL
LGAHALGLRNILCITGDPTSIGDYPHATSVFDIDSVGLIRAVRSMNDGRDLMGNTIEHHT
SFFIACAANPIADDMDVEIRKLERKIAAGADVIYTQPLYELRTLEQFLKRMEQWQRPVMV
GLLPLRSYKHAEFLHNEIPGMAIPDSIRDRLRHAGERAASVGVQLTIEFLKEAKAMVAGA
YFMPPFKKYDIIPPILESCL
>A0A2E3SRD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVSELLRSGKPTLFTFELLPPLKGNTIQTIYDAIDPLLEFEPSYINVTYHQSETVYTEK
KGLIEKKIVRKRPGTVAISTAIKNKYKITVVPHLICGGFTKEETEDALIELNFLGIHNIL
ALRGDPPKGSRVFIPEENGHRYTNELIEQIMDLNKGSYLSEDLKHNYATEFSVGVAGYPE
KHIEAPNMDADLQNLKRKVDAGAEYIVTQLFFDNQRFFEFVDNCRKIGIDVPIIPGIKPL
STLNDIKMLPQTFAIDLPHDLMKEASKCKTSKEVRQIGIEWCTMQSKELKAAGVPGIHYY
TLSQSDNIARIASLVF
>T0UH22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris TIFN7|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNITAVAHLPAAYLDKTQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>A0A2E2M8S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSTRFNSPTLAGRIKVSFEFFPPKNGDMESQLWESISRLAPFNPDFVSVTYGAGGSTKQP
TLNTVARIIGETGLSPAAHLTCVDATREDVDQVAREFAASGVKHFVALRGDPAEGVGATY
RPHPGGYENAAALARGLRGLGDFEISVAAYPEKHPESPDFALDIDLLKRKVDAGATRALT
QFFYDNDAYERYVERVRKAGIFVPIVPGIMPIHNFAQVARFATMCGASVPDLLARRFEGL
ENDPETRAMVATAVAAEQVHDLVERGVDEFHFYTMNRAKLVYAICHLLGLRGNGGKNGKG
VDAAA
>A0A0T0PWY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf412|TrEMBL
MNFSVRQMTEAARALDAPLYADVGGDVEVSFEFSPPKTDKAEATLWESIETLAPLSPRFL
SVTYGAGGSTRDRTHATVARIARETTVPAAAHLTCVEATRDEIDAVAEEYWAAGVRHIVA
LRGDPPAGAQDYAPHPGGYENAAALVEGLRRLHPFEISVAAYPECHPSSANLAADLDNLR
RKLDAGANRAITQFFFEPDTFFRYRDAAAAAGIDAEIVPGVMPVGSFAGIRRMAAMCGTD
VPGWLDRLFEGLDDKPAARQLVAATVAAELCRKLYAGGVKQFHFYTMNKAELSFAICHLL
GVRSAGRAAAEAA
>A0A0W0GGD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalogenimonas alkenigignens|TrEMBL
MNVRDIYNKKGIVFSFELFPPKTEEAAEELFTTIKDLKPLELSCVSVTYGAGGSTRELTH
DLLVRIHKETDLTVISHLTCVGSTRAEICQILEKYRASGIENILALRGDPPKGQTSFVPE
VGGFSYAIELVRFIKDNFPEMGVGVAGYPEGHPQTPNRLTEIQYLKAKVDAGADYICTQL
FFDNRDFYDFRERCALAGINVPIVAGISPITSVKMMKRMADLAAGTHFPAPLLRAIERAE
NEECVRDVGVHWAAEQVRDLVDKGVDGIHFYTLNKSDATLQIYKSLGVTSSKKLA
>A0A3M1X295|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MRVIDHLLSTKNPTVSLEIIPPRRGRNIEKLHQAIESVLPFRPPFIDVTSHAAEVIWEEM
PDGSFKKKVKRKSPGTFGLCAAMKYKFNVEPVPHLLCGGFTREETEDALIELQYLGIENV
LAIRGDKANHRPIPQDRTANNYAVDLVHQIDRMNHGRYIDDLIDATPTNFCIGVSCYPEK
HFEAPNLDFDLQILKQKQDAGAHYAVSQMFYDTGKFLAYVEKARAAGITMPIIPGMKIMT
GKGQLTRLPSIFHIDIPQELTERMLAAKTRAEEIKIGVDWAYRQSLELLEAGIPYLHFYI
MQNTKPFLALMDKLKKKV
>A0A1A0KW21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia sp. 852002-20019_SCH5090214|TrEMBL
MGQLGRRPDGTIPFSVEFNPPRDAAAEARLWRAAREFERMHPAFVSMTYGAGGSTRDRTA
RITGQLARETTLLTVAHLTAVGHSVAELRSIVGSYADAGIRNMLVLRGDPPGDPLGEWRK
HPDGVEYAEELVRMVCELGDFHVGVASFPQGHYRSPDLEHDTRYLVSKLRAGAEYSITQM
FFDVEHYLRLRDRVAAYDAEQGAKPIIPELMPITSLRTVQRAEELSGRPLPARVMQRLEQ
AAGNDPEANRNAVRAVGIEIATEIGQRLIDEGAPCLHFITLNFAKATTEVLTNLGYTVTP
AAVSA
>A0A432JP24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKITDHIKQADKTLFSFEILPPLKGENIEHINQNIERLLEFKPSFIDVTYHQ
>A0A2V2Z2K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus cellulosilyticus|TrEMBL
MFRESILNKKAGIITYGMTPPKESSSVEKIAEISHKQVERLKNVDIDALILYDVQEESDR
VEEERPFPYMAMLDPETYSEQYLQALDVPKIIYRCVGKYSEAELTNWLKKSSDKDRFSVF
VGASSSGQKVTLDLSEAYRLSGQHNCDLTFGGVIIPERHTKKKDEHMRVVNKMKHGCSFF
VSQATYNVEASKSFLSDYYHYCNELEIEMVPILFNLAPCGSTKTLAFMKWLGISIPRWLE
NELKYSSDVLDKSIQLTNKIFEELLEFGLEKGIPVGCSVESVSTRKIEIEASIQMVKDIK
SLIDKKQLVQIVR
>I3YWF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aequorivita sublithincola (strain DSM 14238 / LMG 21431 / ACAM 643 / 9-3)|TrEMBL
MKVTEHIKNGNGKTQFSFEILPPLKGENIHSIFSNIDPLMEFKPPYINVTYHREEYVFKE
LKGGLIEKKVVRKRPGTVGICAAIQNRYHVDAVPHILCGGFSKEETENFLIDLQFLGIDN
VMALRGDAVKSETYFTPEKNGHKYACHLVSQINAMNKGFYLDDELQNTFPTDFCVGVAGY
SEKHMEAPSSESDIHFLKKKIKNGAEYIVTQMFFDNEKFFQFEKKCRAEGITVPIIPGLK
PIAVKSHLNLIPHRFKVDLPDALVMEVVKAKDNKAVRQIGIDWCVQQSQELVKAGVPFLH
YYSMGKSSNIKEIASRVF
>A0A2T5YT65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter mucosus|TrEMBL
MKVTDHFKNANGKTLFTFEILPPLKGENMKTLFNHIDPLMEFKPPFIDVTYHREEYVYKQ
RENGLLEKRTTRKRPGTVGICAAIQNHYRVDTVPHLICGGFNKEETENALIDLHFLGIDN
VLALRGDCVKSEQRFVPEPGGHNYATELIEQVANMNNGVYLDDEQAYHNGTDFCIGVAGY
PEKHFEAPNMKSDLRWLKKKIELGADYIVTQMFFDNQKYFDFVNRCREEGITVPIIPGLK
PMTTKTQLTLLPSLFHIEIPCALAEAIEDCPDNKAAAQVGVEWAIQQSKELMEFGVPCLH
YYSMGKSDSVRKVAEALF
>A0A1M3IA49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium 63-6|TrEMBL
MSYAAIHPDWEKPRANMVDGYSLEMTAKEIEGLKEAASKIRPGTQIAVTFLPGEEMSQRV
ECAKLVRDLGFEPIVHLSARRFTSEAELEQYLSDITSQAAVKRVFIIAGDPPEPEGPYSD
SLQIIETGLLEKYGIEIVGIGGHPEGHPNVSKPDLWIWMEKKIEAIRARGMTPLVVTQFA
FDDDAIIEWVKEMRGRGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGISLTN
LIGSAGPDKLVNSLDKGLTEEAGRVRLHLYPFGALTASAEWINNYAAKH
>A0A537JBY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MTVIEHINQAKDTIISFEILPPLKGKGITAIYEHLDPLMEFKPSFINVTYHRSETMFKKK
PDGTFEKVEVRKRPGTVAICAAIMNHYKVDAVPHLICGGFTKNETEDALIDLNFLGVDNL
LIIRGDAPKNEAFFEPEPGGHRYAIDLMKQVASMNNGIYLEEDLKGVVKTKFCIGIAGYP
EKHFEAPNMETDLSFLKAKVDSGAEYIITQMFFDNQKYFDFVKRCRDAGITIPIIPGLKP
ITTKKQLTVIPRTFYVDIPSDLANEIIKCKIDDEVAQVGTEWLTEQSRELKKFGVPVLHY
YTLGKPRVIANVVRSI
>A0A2S0WV92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces badenianii|TrEMBL
MAPTASDASGADCRSGLPLSFELFPPRTDAAALALGRTIDRLAEVDPAFISVTFGAGGSS
RARSLTVLRYMLEHTHVEAMAHLTCVGSSHAEANRLVREFLDAGITSFLALRGDPPADAD
PDAGIGDLGSAAELVQLIHRVQEEREPFEQVGVPGNPGASRIRERPRPERVAVAAFPTGH
PRSRGVGQDVDTLLAKEIAGANLAITQLFWRADDYLGFVDRARAGGVTIPILPGIMPVTT
PARLSRLTELTGVEPPAELSIDLEIEPDASAQAELGITFATRLSTEVIAGGAPGLHLYTF
NRHEAVLDVVERLGLRADRLADERNTAR
>A0A524MM90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonadales bacterium|TrEMBL
MESQKQLMRAFSFEFFPPQTPEGVERLRATRQKLVQLKPKFFSVTFGAGGSTQDRTFETV
LEIQAEGYTEAAPHLSCIGSTSANIRYLLQRYLDNGIRYVVALRGDLPSGMAQPGEFRYA
TELVAFIRKEFGDVFHIEVAAYPEYHPQASSAQSDLQNFKRKVEAGADSAITQYFYNADA
YFRFVDACEAANIKIPIVPGIMPINKFAQLARFSDTCGAEIPRWLKKKMEGFGDDSASIR
AYGLDVVTDLCSQLLDAGAPGLHFYTMNSPNLTTTIWQRLGFQIQPQ
>A0A2K6UBG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saimiri boliviensis boliviensis|TrEMBL
MDHRKARVLPAGHYCPSLGIRASQAGSVRFSVPPSISRNLAMVNEARGNGSLNPCLEGSA
SSGSESSKDSSRCSTPGLDPDRHERLLEKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCHQRLEEIT
GHLHKAKQLGLKNILALRGDPTGDQWEEEEGGFNHAVDLVKHIRSEFGDYFDICVAGYPK
GHPDAESFEADVKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDVGITCPILPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVCLCRELLASGLVPGLH
FYTLNREVATTEVLKRLGLWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKNYYLFYLKSKSPREELLKMWGEELASEESVFEVFVHYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGVLTINSQPNINGKPSSDPIVG
WGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHLVNVKGENITNAPGLQPNAV
TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEESSPSRAIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDTLELLNRPTQNEREAEAL
>A0A0S8KMC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium SM23_84|TrEMBL
MAEYLSRLQESLVDQDTFSITWELVPGRGAFEKAQKELVLAAEKAAKGGKIHALTMTDNP
GGNPAISPEMLGMEIERLGIEPLVHFTCKDKNRNQLEALLHGLERAAVRNLLIMTGDYTY
TGYQGRPKPVFDVDSTHLLYLISHMNRGLMVPTPRGATTLTPTHFFAGACVSPFKALESE
LMGQYYKLEKKLIAGAQFIVTQVGYDARKFHEVLLTMKRLGYEHVPVIGNIYVLPRGTAR
VMNRGQIPGTVVTDELLSVIEEESQAPDKGKGKRLERAAKMYAFMKGMGFAGVHIGGHGL
KYEDVETIIEMGEDLSANWHDLLPEFDFPQPNGWYYFEKDSQTGLNTEVPVDRSKDRPRT
PLSFRAFRLLHSLLFDERGALFKPMRALCAAIDGSSFEHVFTRLEHLAKVVTNECMHCGD
CAIFDVAYLCPMSQCPKNQRNGPCGGGFEGWCEVYPGTKKCVYVRAYDRLKSRGEEDSLV
AYHVPPADYDLRWTSSWLNFYMGRDHTAKRLSILPPSQKKRA
>A0A6G1I5E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichodelitschia bisporula|TrEMBL
MHISDKLADASNGGKPTFSFEFFPAKTAQGIQNLYDRMDRMHGFGPSYIDITWGAGGRSA
HLTCEMVHTAQTALGLETCMHLTCTDMPKSKIDDALKEAYNSGCTNILALRGDPPREKEQ
WEATSGGFRYAKDLVTYIRDAYGDHFDIGVAGYSERCEDNEDVDELVDHLKEKVDAGATF
VVTQMFYDADIFLDWVRKCRAKGITVPIIPGIMPISTYAAFIRRANGPMRCKIPDSWMAA
LEPVKNNDVEVREIGKNLVVELCRKLLDSGLIHHLHFYTMNLAQATRMVLQDLGLLPDIE
APLEKPLPWRQSLGLRRKDENVRPIFWRNRGRSYVARTQEWDEFPNGRWGDSRSPAFGEL
DAYGVGLQGSNEHYVKLWGTPTSVKDVSNLFIKYMQGKVDSLPWSDQPISLEAGDIKDKL
IALNERGLLTINSQPAVDGAKSSDPVHGWGPRGGYVYQKAYLEVLISSELIAELITRIER
DPDLTYYAVNKAGDLKTNAPGDGPNAVTWGVFPGKEIIQPTIVETISFLAWKDEFFRLGK
DWADCHSASTPTRYLIEDLMDTWYLVNIVHNDFRQKHAIFELFDGLVVPDIDRPLHEVRD
PATTNGASTAPADVHK
>A0A6P1FNN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. VKM Ac-2801|TrEMBL
MTRARFEIIPADDIGERAARAFPDPSAVTLTVTSLPKHGTERTVDCAVALAGRGFRVVPH
LAARNVEGRGALQKVLGRMGEAGIDEAFVISGDASSAAGAYSTSLELIRDAREISPGLAL
DIAGYPEGHPHLSDESIERHLRERAPFIRSIVTQMCFDVDAVVGYADRLRETGIAADLWA
GVPGPVERSRLLTLGARIGVGSSLGFLKRSTSVAGGLLRGRRFDPSAFVARLEAAAGDRL
AGLHVYTFNELDSLAAFG
>A0A7Y6YII4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriia bacterium|TrEMBL
MRIDQHIANAQKKEQTLFTFEILPPLKGQTIHDIYQNIDPLMEFKPPFINVTYHREQVVY
KRLPNGLLEQKVVRKRPGTVGICAALMNRYQVDPVPHLLCGGFSKEDTENALIDLDFLGV
ENVLALRGDGMQDQMYFVPEADGHTYASELVEQIVEMNQGKYLDEELANNHATNFSIGVA
GYPEKHFEAPSLNVDVSHLKKKVDAGANYIVTQLFFDNKKYFEFVDKCREAGITVPIIPG
LKPIATKRHLSMLPHRFHVDLPDELAMAVMQAKDNAEVRQIGVEWAIQQSKELKAAGIPV
IHFYSMGKSDNIYAIAKEMF
>A0A1P8KH81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHKVAGIVITPHMLRVLAQEKQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVKT
KNELVPELAYYSRQLSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASFWENAPAAKA
LLKTEFISKQGIVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A1F9DBB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_54_18|TrEMBL
MKTGSRLEKVLEKGAFAVTSECGPPRGADPDVIREKGKLLEGVVDAVNITDCQTSVVRMS
SLSACLILKEMGFDPILQMVTRDRNRIAIQSDVLGAAALGINNILCLSGDHQRFGDHPQA
KNVYDIDSIQLIMTVKKMRDEKKFLNDQEMTKAPVLFIGAAENPFADPLEIRALRLAKKA
AAGVEFIQTQCIFNLDRFAEWMREVVDMGLHEKVAILAGVTPLKSVGMGKYMKSQVPGMD
VPDAVIERLKGVPKEKQGAEGIKICIETIQRLREMKGVRGVHIMAIEWEEKVSEIAKGAD
LLPRPKV
>A0A0A2MIQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium rivuli WB 3.3-2 = DSM 21788|TrEMBL
MKVTEHIANANGKTQFSFEILPPLKGQNIQSIFDSIDPLMEFDPPFIDVTYHREEYEYKE
LPSGLLEKKVVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VVALRGDAVKTETYFRAEKEGNQYATELVTQVANLNNGIYLDADLQNTSATNFCIGVAGY
PEKHMEAPSFDSDIYFLKQKIKNGAEYIITQLFFDNQRFFDFVSKCRKEGITVPIIPGLK
PIATKKQLNMIPHRFKVDIPDDLIMEVVRAKDNDAVKQVGVEWCIAQSKELIKAGIPVLH
YYSMGKPDNIKAIAKEIF
>F2QR20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1)|TrEMBL
MKITEKLSSAHRREDAPPTFSFEFFTPKTAQGVQNLYDRMDRMYNLSPQFIDITWNAGGR
SSNLTCEMINTAQTVLGLETCMHLTCTNMTLEVIDEALKSAYDSGCQNILALRGDPPLDG
SESTGCFRYAKDLIKHIKEKYGDHFCIGVAAYPEGHPDEPDVDRLIEILKEKQDAGGDFM
ITQMFYDVEQFITWCKKVRDYGITIPIIPGIMPISTYASFSRRAKWCQINVPSWFQKQLD
ASKDDDSEVRCLGTQLVADMCLKLVESGYVNHLHFYTMNLEKSTIMVLEKLQLIDTHNQP
VASVRDCGVESQVTVPWRRSLNPTRVNESIRPIFWSNRKFTYISRTSNWDEFPNGRWGDS
RSPAFGEVDLCDGDLIRHSPKRAVELWGKPQSIDDVIDLFVRYLQGNLSSLPWSDGETSK
EINVLLDDLLALNRQGILTINSQPCVNGLPSNHNVHGWGPSNGFVYQKQYLEFFIPAKFL
TKLISNIEELNKSYSSNFNTLTFYAVNAQGELITNSKEDDINAVTWGIFPGKEVVQPTIV
ERCSFLAWKDEAFRVFKAWSSLFKDQDQDEFEVLRDSKTRAVLDKLHDEYFLVNIVDNNY
VQNPNVKIFDLFKTLH
>A0A1E4QGK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa NIES-98|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGSLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPVHN
>A0A2S9PSS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ST5x|TrEMBL
MTTSSAPSFSFEFFPPKTEAGERTLWRALREVEALRPDFVSVTYGAGGSSRDRTVAVTRR
IAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGIRDVLVLRGDPPGDPQGPWTPHPAGL
THARQLVELVRSLGDFRIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFHVE
DYLRLRDRVAAAGCDIPIIPEIMPATDVRQIARFAELSGASFPTDLADRLHAARHDPAEG
HRVGVATATAMAERLLAEGAPGLHYITLNKSTATREIHHNVLGLIPSPSLPLQRSTRVCQ
PSL
>A0A2P1NP18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pulveribacter suum|TrEMBL
MSTTTAALPVSFEFFPTKTPEGAEKLRAVRQQLYARAPQFCSVTYGAGGSTQQGTFAAVR
EILAEGVDAASHFSCIGATKSGVREQLAQLKAMGVKRLVALRGDLPSGYGLGGEFHYASD
LVAFIRAETGDDFFIEVAAYPEIHPQARSAETDLNAFAAKVRAGADSAITQYFFNADAYQ
RFVQDTRRLGLDVPVVPGIMPIMGASQLLRFSDACGAEVPRWIRLRLQGFGDDVASIRAF
GLDVVTQLCEQLVRAGAPGLHFYTMNQSAATLAICERLKL
>A0A0M2VJC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arsukibacterium sp. MJ3|TrEMBL
MAFANAQYLDAINRNLQDVQGKVNVSFEFFPPKTAQMEQTLWQSIERLAPLTPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDATKQQLIDIARDYWDNGIRHIVALRGD
LPVNSTATPELYATDLVEILRSVADFDISVAAYPEVHPQAPNAQFDLLNLKRKVDAGASR
AITQFFFDSEKFLRYRDRCAAIGIDVDIIPGILPVTNFQQLQKFAGLTNVAIPDWMNKAY
QGLDDDPTTRNLVAANIAMEMVKVLSREGVAQFHFYTLNRSELSYAICHLLGVRPVL
>A0A432IU82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriia bacterium|TrEMBL
TEYLLVDCQYLEIENVMALRGDARKEEKYFTPTKGGHQYATELVKQIQDINEGNYLHDTI
EASDLSSFCIGVAGYPEKHMEAPSLQSDLKRLKEKVDLGADYVVTQMFFDNQKFFAFVEA
ARAMGINVPIIPGIKPIAVKNHLQLLPQVFRVDIPQDLIDAVEACKTNQDVRKVGVEWAI
QQSRELREYGVPVLHYYSMGKSDNVEAIAKELF
>A0A646MQI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A5P9XU15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus thiooxidans ATCC 19377|TrEMBL
MAHSVEFFPPKNAAGEERLRETIAALLPLGPEYASVTFGAGGSTRERTFATVDMIRKDYD
LEAVPHLSCIGSTESGIREILEDYRAQGIQRIVALRGDLPEGMSNPGHFEYAADLVGFIR
QFGGFKIYVAGYPEVHPKAVSAEEDLQHLVEKVQSGADAVITQYFYNPDAYLQLRDDLQR
RGVEVPIVVGVMPITNFEQISRFSAMCGAELPQYLRRRMEAYGEDLQSQYQLGIELLSRQ
CETLLAQGAPSLHFYTLNQSEATTAIWQNLGL
>A0A0Q8AZ70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Root562|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VDFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKANAGANSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTPSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A373NRQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF31-14BH|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPE
AMKQAGIAYATDQIIDLLANGVNNIHIYSMNKPEIAIAIMNNLSEIIKC
>A0A535W1K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKNLFLEQLQQHTLLCDGAMGSLLYARGVSYEQCFDALNLTQPGLIQSIHNEYINAGAQI
IETNTFGANRAKLEAYNLGESVREINFRAAKLASEAREISGQPVFIAGAVGPSGRPLQAP
DEQRLSELRTIFREQIEALLIGGVELLILETFSSLPELRQAVLAAQEVGGLPIVAQMSFY
EDGHTLSGQSAARVAAVLNDLGVDVMGANCSVGPAATLDVLQEMIAAVKLHDEQAHKGSY
LFSAQPNAGLPTRIGNRFFYMATPDYFADYALRFARTGVQLIGGCCGTTPRHIAAMRKAL
DEHNGVSTRYSNAISTEAEEARPVEITTVKASITALIEEEILLPQQGSMTRLQEKLAARE
FVVSVELDPPKGLNPSKIMEGAVLLQKAGVDCINIADSPMARVRMGCIALARLLQDHLGL
ETIIHFTTRDRNLMALQSELLGAHALGIRNILALTGDPLRLGDYPNTTGVWDVDSIGLIR
VLRSMNEGHDAAGSSIGAQASFHIGTALNLNETDEEFESEIEKYLSKIEAGAHFIMTQPI
YELTPLVRFLERVGQPPIPLILGCIPLHSSRHAEYLHNEVPGITIPDDVRQRMRMAGEHG
HEEGLKLAQELLNVARSMVQGVYLMPSYGRYDVVSTLAQMLQMQPTS
>A0A6L7UXP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
PSGGELPKAEGGLPAFDTAAELAEFIRERADWDIGVAAHPEGHPMAASVEADLAHQAAKL
KQADFAITQFFFDVDHYARFVDRLRSRGVDTPVIPGIMPPTNVAGIERMSALNGTEFPQD
IRNRLEQADSAADRREIGVEVAVRLGRALLDVGAPGLHIYTMNFARAAAEVAAALGWPAT
>A0A2N5K6X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTHPFMTRLQRAPLLADGAMGTQLYNHGIDFDQCFDALNLTQPRVVAAIHRAYIDSGAEL
IETNTYGANRFKLEPYGLQDRVREINFRAMKIARDVREIAGATTFIAGAVGPLGKLLEPY
GQVTAEQARDAFGEQIGALYEQGADLLLFETFSDLREILLAIEVARGICDLPIVAQMTFA
EDGRTALGHTPAEVVTKLRAAGVEVVGVNCSVGSQRVFNVVEAMHVAAPDMRLAAQPNAG
FPTERHNRVFYPSSPEYMARYAKRMVEELGVSLVGGCCGTTPEHTAAMQAALRELRPDAP
ARHSHDAPVTSGPKPAVVAATAAPTKLAEQLQARKFVVSVEIDPPRGHNPQKCIDGARML
QEAGVQFINVADSPMSRVRMAALAMCTMIQDRTGLETILHFTTRDRSLMGLQSDLLGAHA
MNVRNILALKGDPPSLANYPGTKGVFDVDTIGLVKVISGMNRGVDTAGDDIGVPTVFNIG
VALDVNAADPHYEIERLHQKVAAGAQFAMTQIAYDAVALRSFLERLGPPPIPLLLGVLPL
QSFRQAEFLKNEVPGIAPTDEALHRMKLAGPEGRKEGVKMAQELLQEVKSLVNGVYIMPS
FGRYEVAAEVLKVL
>A0A832HUH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MQWIRDIYEGKKGPVISFELFPPKTPEGEANLLGRTLPELLALKPDYCSVTYGAGGGTRD
RTLRVIEQLACRHGVVTLAHLTCVNSTRTEIGNVVAQLRGMGVTNILALRGDPPAGSNGF
EKIPGGFEYAWELVRYLKEEGGFSIGVAGFPEGHPACKEGKLADWEHLVAKIGYGADFVL
TQLFFDNADFFQFRDYLRRRGVKIPIVPGIIPILSAAQIEKFTSLCGARLPDKLRAELAR
FADNDDACAAFGIEYATRQCRELLDAGVPGLHFYTLNKARSTREVLRRLGLA
>A0A7C2KBW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MDATHSHQDPRSESGGNGFLSGSRLERVLRAGHFAVTAELGPPQNANPEVIRQKARLLAG
VCDAANITDNQTAIVRMSSIGAGVLALQEGLEPVIQMTCRDRNRLAMQSDLLGAYALGLR
NLLCLTGDHQSFGNHPTAKNVHDLDSLQLIQMVVGMRDGKQFQCGDAIQGVEPRFFVGAA
ANPFGDPFDWRPLRLAKKVKAGASFIQTQLIYNVARFAEFMERVRELGLHRQMYLLAGIG
PLKSPGMARYMRDEVPGLDVPNEFVDRMTAAADGIDKEDKKARAAAWKAEGIRIAIELVQ
QVRQIEGVAGIHLMAIEWEEAVRPIVEGAGLLPRPEVVAGPRPEPVAGPRPEPVEGAAA
>A0A535IPT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSPFLERLNHGPLLCDGAMGTQLYEHGIPFDDCFDALNTTHPELVKQIHRAYLDAGADL
IETNTFGANRIKLREHGLDEQVRAINEAGVRLARESIRECGRPAFVLASVGPLGRRLAPL
GQLTRAEALSALREQISALVSAQPDALIFETISDLAEIQLAIATARELTELPIIAQMTFA
EDARTILGFSPQQFAEKMRELKQVDVIGANCSIGPGRLFPVVEAMLPYADGFKVSAQPNA
GWPEQVGDRLIYPSTPEYFARFAERAVEAGVSILGGCCGTTPEHIRAMRRALDQLSISEM
DFDRVEVVSPPSPRPAPAAHGPTLLQQKLAGGKFVVSVEVDPPRGGDAQPLLEAAQWLRQ
NGVDVLNVADTPMARMRMSPWALSYLVQSNVGMETVLHFPTRGRNLLRVMCDLLAAHALG
LRNILVVMGDPPSHGDYPDASDQSDVVPSGLVRLIKQQLNAGQDGVGKSIAQATSFHVGV
ALNMGADNLDKEIGIFKKKIDAGADFALTQPVYEPSAAARFVRRARERLGDIPIPILMGL
LPLASTRHAEFLHNELPGFALPEAVRERMRLAGKRGRSEGIRLAQEILLESRPYVQGVYV
MPAFERWQTVADVISVLALEHAH
>A0A535WFL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MDRFTARLEERGALLFDGAMGTELWARGVPPDHCLEEVNLSDPSLVRAIHRDYIAAGADV
IETNTFGANRFRLAEHYLEGRGREILEQGAKLAVEARNMSGRPVLVAGSVGPLGKPLEPI
GAIKLSAAERIYGEIVESLAESGVDLLIFETFTSVGELELAVRVAREAAHQLPVVACMSL
DDDADVGILRAVSGLGPAALGFNCGSGPQAALQIARRLHEAGLGPIAVIPNAGLPQRVSG
RLVYAAGPRYFAESVEPLLQAGARVLGGCCGTRPEHISAMRAALDASRNAGDSIAPAVRV
RRPKAESESNPPASRLAASLARGDFVISVELTPPRGVDPKRMLDGARLLKEAGVDYANVT
DSAMARVRMGVITCSALVQQQVGLEAIAHFTTRDRNVMAIQSELIGAHALGIRNILCLRG
DPPKAGDNAVGIWEVNSVGLINIVANLNRGLDANASPLGQPASFLIGAAVNPNARDIRRE
IGLLDRKVKAGAGFVVTQPIYELDAFERFLEAAGDLPIPLLVGVLPLISGRHAEYLDNEV
PGITVPDAIKERIRAAGEQAAEVGVEIAVEFLDAARRWVRGAYVIPSHGRYDLAAVIVQR
AREMVG
>A0A6L7Q0I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIRKILNQQRTISFEFFPPREADGVPGVIDVVKDLQRFNPDFVSVTYGAGGGTRAFTEE
ITMRLKAETDLDVMAHLTCVAQNRADVHGVLQRLQTAGIENVIALRGDRPPDLADAEPGP
DEFPHATDLITHIRDNFDFGIAGACYPEGHTESESLDTDIAYARMKQDLGADFLITQLFY
DNAYFYDLLDRAAAAGINIPIIPGVLPILSTPQIRRFTSLCGATIPTELDVRLERYADDN
RAVREIGIEHATRQAEDLWANGVPGIHFYVLNRRYSVSHILESLNINGHNGK
>A0A8H9J9D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPKLPFLERLDSGIPVVADGAMATQLHRSGLPMATCFEAVNLADPDKIYAVHSAYLAAGA
ELLETNTFGANRQKLSEHGLSDKLAEINGAAVEIARRAIADSGRDAYIAGSMGPLGQKIR
PYGPISREDARGMFFEQAAALIAAGVDVILLETFADHHELLEALAAVRLVSPDVPVVTHA
TFASDDRTLTGFTPAKVAADLVRAGADVIGVNCAGGPAQISHILETMHTCVPRARLSAMP
NAGFPESVNGRVMYPASAEYFGDYALTFQALGARIVGGCCGSTPDHIAAMRRAIDAAAGG
ERSLPIIHVEEAAVSEDQIAPAAPTDFAERLASGQFTVTVEMAPPRSFSVERLIRSAHLL
RDAGAHILDVADTPAARMRMSPYAVAHVIQSQVGVETVLHFPTRGRNLLRIQGDLLAAHA
LGLRNVFVTMGDPTRIGDYPDANDSYDIVPSKLIGLIKHSMNRGVDQAGNSIGAPASFTV
GCALNMGADNLDHEIKILGAKLAAGADFALGQPVYEPWRIERFLTRYEQVTGRVFDLPVL
LGVLPLFSLRHAQFLHNEIPGIVIPQTILSRMEQAGDDAPYEGVRVAQELLQATASYVRG
AYIIPAFGRYDLAAEVVAATPVRA
>A0A7C4P932|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPVFTPGRRWQPPYLPFKTISFKQRALVAIERWVKGPLFGCRMCGNCLLQETAFICPMEC
PKGIRNGPCGGSTQEHCYVDETRPCIWYKIYDRAFKMGREELLLEVLPPLDWDKVGGETW
GDVVAQLRKVGVRSFVGGLLSRDAVQRTMVWDAVFRPVRQPDWWQGDAEYHPPAYNEPVS
ELERRLKAGEFVVTSEVAPPLTTSTKKLISNIELIKPYVAAINFTDSPSATPRMSSWACS
ALAIQAGAEPVMQIAARDRTRTGLQAEVLGAAALGVRNILCLSGDSMRMAPEPRGRMDIV
DLDSVQMLWVLRRMRDEGKYLDGRSMKFPPKFFLGAAASPFASEPRFQAIREHKKVNAGA
QFFQTNLVFDPDGLEVWLNALAQRNILDKVYILVGITPLKSLKMAEYMHNEVPGVTIPEK
YLKRMAEAGDRAEEEGVQIALELIEAIKGKQGVNGIHLMAVGWEEIVPRIVVESGLAAPR
ATTATADAPAPLPITF
>A0A5B8BY55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Georgenia yuyongxinii|TrEMBL
MSTSSLLCVTTATHPTVSFELFPPRKPELYEAVWQRVLRMAEAGPDFFSVTYGASGSSRE
ASGELVRRLLAETSVPPIAHLTCVGADREQLAARVRGLLRAGVRDFLALRGDPPDGQTTW
APPSGGLARSSDLVALIREVEADELGYGPAARAGAVARSGPAARAGAAGEPPSVVAQDLG
VVPADVVSVAVAAYPSGTSHTREEELVALREKQDAGADFAITQVFYNAEAYASLVADARD
AGVHIPILPGILPLTDPRRLHRLEALSGVPVPADLDALLGCDDDAERQRRGIDATIALID
GVLEAGAPGLHLYTFNQDRPALDVLEHLRAGGLRNPALLTPPAVQRQSAAG
>A0A497A3T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKTRSNLAKTLETGQFAVTAEISSPQSMDFETIRKNINLIKGYVDAFNVPDGQAAVVAMA
SWAVCLVGMEEGIDAIAHMTCRDRNRIALQMDILAISAYGVNNILCVSGDPISFGNHPEA
KPVFDLDSIQLIRMVKKLRDEGKFDNGESIVGTKPKLFIGAALNPFTRPLESAVGRLKEK
VTAGADFVQTQPVYNIEEFKKWMELLRAEGLYKEIKILAGITPVTSLAAARYMKTKIPNV
DIPEIIIERLKKARNKEEAAEEGLKIAVETIKQLKQTEGVSGVHIMTLQREELIPKICKA
ASLYPRP
>A0A182FF44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles albimanus|TrEMBL
MPWISDENLRYEDDFGQMPSLRLADQLRREQFTVVNHLSCYNLTEAQVDKLLSSQPTIRN
LFIVRGDTVNPNQRFQHSAQLVQHLRQYESTRTTTAAPKLTIGVGGYPGGHAESPSQEDE
VRHLADKVALGADFLLTQTLYDAASFFRYRDRCRAAGITIPIIPGIYLPHSYRQLQSLLN
ITRVAMTPAVRATFEEHRQDTPEAFEAFVVEYFVELVRELLQSNALEPGISSSEPVGLVH
FFTFNKFSLLEKVISQLPFGQQ
>A0A535M0L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQHDFLEQLQQHPLLCDGAMGTLLYARGIAYERCFDELNLTRPALIQGIHSEYISAGAQI
IETNTFGANRAKLEAYNLEGRVRDINRHAVKLAREAREISGQSVFIAGAVGPSGRPLQAP
DEQRLSELRAIFREQIDALLVGGADLLILETFSSLAELRQAVLAAQDVGGLPIVAQMSFY
EDGHTLSGQSPARVAAVLNDLGIDVMGANCSVGPAATLDVLQEMIAAARLFLDNEQAIPQ
MFSAQPNAGLPTRIGNRFFYMATPDYFADYAVRFARAGVQLIGGCCGTTPHHTAAMRKAL
DDAYGATTPSIPGSSRETLHTKPVEITNGKVTIAGLIEEEVILPQQGTKTRLQEKLAARE
FVVSVELDPPKGLNPAKILEGAAMLQKVGVDFINIADSPMARVRMGCIALARLIQDHLGI
ETIIHFTTRDRNLMALQSELLGAHALGIRNILSLTGDPLHVGDYPNTTGVWDLDSVGLIQ
VLRRMNEGHDAAGSSIGAQASFHIGMALNLNMTEQETEQEIDKYRRKIEAGAHFIMTQPI
YELARLERFLARAGKPPIPMLLGCIPLHSSRHAEFLHNEVPGITIPDDVRSRMRAAGDQG
HEEGLKLSQELLTSARSMIEGVYLMPSYGRYDVVSKLTKMLQMQPTP
>A0A535FI57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAYAFIEHLRQHPLLCDGAMGTLLHARGVTYEQCFDALNLTQSELIQAIHREYINAGAQV
IETNTFGANRARLEAYNLTERVRDINFRAARLAIEAREVAGQPVYVAGAVGPSGLPLQAP
NEQRLSELRTIFREQIEALQEGGVELLILETFTNLAELRQAVLAAKEVGGLPIIAQMSFY
EDGHTLSGQSATRVATVLCDLGVDVIGANCCVGPAATLDVLHEMIIAVQQQADSLGLTIP
LFSAQPNAGLPTRFGNRFFYVSTPDYFADYALRFARAGVRLIGGCCGTTPRHIVAMRKAL
DEQYSRRVPFTAAVPPSMDLSKTPGEASGKTTLTSVIEEELLLPQQGTKTKLQEKLATKD
FVISVELDPPKGLNPGKLLEGAAQLQQVGVDCINIADSPMASVRMSCIALARLIQDHLGI
ETIIHFTTRDRNLMALQSELLGAHALGIRNILALTGDPLRV
>A0A2E6MHC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MHSLEIVPKQLDRLKFLPDNKFEDVFVAFIPGDNYTNIVNASKSLLELNYNPIPHIPART
INNEDELDNFLKNLHSIGVKEVLVIGGSPKKQEGPFSKSMDLFKTGLFGKYKFKINIAGH
PEGNPDDLDSDINLLEKSKWLYENNFIFSIVTQWTLDIDKTNAWILKIKNEIIKRNLGEN
VNIKIGIAGPAKLTTLINYAKICGVSATALIVRNKKLSLTKLVKHNPSEIISGLENYDQL
HFFPFGGIKELTGWIEKKEG
>A0A535HYU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGTQSEGRPWAALLRTPRYEIFPTDDVLDVVARHVPKEVTITVTASPRRGLPATVQLAIQ
LARLGYTVIPHLSARLIRDHAELGQILEAIRPAGIRGIFVVAGDAREPAGDFPDALSLLG
ALPPDHGLAEIGVTGYPESHPFIHDDVTIQAMWDKRRFATYIVSNMSFDPEAVKRWVERV
RRRGVELPIYIGMAGVADPARLLRLSTKIGVADAARFLRGHPSWLARMFRPGGYEPGRFV
NALMPDIAQAERRIAGLHVFTFNEIEPTERWRQDMLRRLQ
>A0A2E7WC38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSMHSLEIVPKQLDRLKFLPINKFEDVFVAFIPGDNYLNIINACRSLLESGYNPIPHIPA
RTIASKEQLEDFLFQLTSLGVKDILVIGGSPKKQEGPFSESMDLFQTGLFSKYVFTINIA
GHPEGNPDDSESDLNLIEKSKWLFENKLNFSIVTQWTLDVEKTNRWIHEIKNKLIQGIDQ
DIKIKIGIAGPAKLTTLINYAKICGVSATALIVRNKKFGLTKLVKHNPTEIINGLKNYDQ
LHFFPFGGIKELSGWMEK
>A0A535SY41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MATFLRTPRYEIFPTDDVLEVVVRYVPREVSITVTASPRRGMPATVLLAVALARSGYTAV
PHLSARMIRDRGELGQILEALRGAGITNVFVIAGDAKQPAGEFPDALALLSALPEDHGLT
EIGVTGYPESHPFIHDDMTIQAMWDKRRFATYIVSNMSFDADTVKRWVERVRRRGVELPI
YIGMAGVADPARLLRLSTKIGVAESARFLRGHPSWLARMFRPGGYEPGRFVGALLPDIAQ
HARRIAGLHVFTFNEIEPTERWRREMLSRLSQGEGA
>A0A535XG40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSEFASLLRGGDFVVTAELNPPKSASSQVVRRRAEALKGYVDAVNVTDSNRAMVAMAAIP
AATIVMAAGVQPIVQMTGRDRNRIALQADVLGAAAIGIDNFVFMSGDDPKQGSHPDAVNV
KDLDGVGLVKMAVGMRDQARFLSGDEIKQPPKMLVGATASPFTKPMEADLAKTSDKINAG
VDFIQTQPVFDLATFSQWLVEVRRGGAREVPIVAGVLVLRSPEQADRMSKIPGLAINSEV
VDRMKAAADPEAEGVAIAVEQVKALRALPGVRGVHLYAIEWPEAVGRVVEGAGLLPRPQA
KVAV
>A0A536HW77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNRERSFLLSNLASLLRQGEFVVTAELNPPKSASGEVVKRRAAVLKGSVDAVNVTDSNRS
VAAMAAIPAALLVREAGVEPIVQITGRDRNRIALQADLLGAAALGLSNFLFMSGDDPKHG
NHPDAVYVKDLDGIGLVKMAVTMRDEHKFLSGDEIRQAPEYFIGATASPFAKPMSADLEK
TVEKVTSGADFLQTQPVFDLATFSQWLAELRRVGGGREAAVLAGVLVLRSVEQAERFGRV
PGVALGQEIVDRLRKAADAEQEGLAMAVEMVKSLRALPGVRGVHLYAIEWPEAVALVAER
AGLLPRPKVKESKP
>A0A535Q060|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIVDMLTRSRPSVSFEFMAPRDESEVDVLERTISALAGHGPDWVSVTYRQRTGEKTLEL
VTRIKRQYHIEAMAHLTCANTVDRTRQVLNWMEREGVANVLTLRGDPPSAGEPFVPADPR
LTHASDLITLVRGSGYRFGLGAACSTERHPESPDLEHEFRYMQLKVEAGAHFLITQLFFD
NRFYFDLVARARAAGIKVPIVPGLMPVPSRRSLAVMTAMSGAT
>A0A536LEQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPAPSRLAGLLRDGRFVVTAELTSTNSADPEATWRLAEVLRGSVDAVNCTDNTGAHVHMS
SLAAAHLLVEKGIEPIMQLTVRDRNRLALQADLLGAAALGIRNIVLMSGDDVTAGDHPEA
RRIYDIDSMQLIEVAAGMRDRGVYLSGRKLEQAPSFFIGAVENPFAPPLEFRPLRLQKKV
RAGADFIQTQLVFDVPLFARFMSMVGDLGLRDKVFIIPSIGIPRSARGARFMRDKVPGLH
VPDAIVDRLEKTPPARQSQEGIQIAVELVKAVREIPGVAGVHLIGIKWEEGVVQVAEAAG
LLPRPTMSPLATVGGSR
>A0A497ADQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKTKSNLEQVLEAGQFAVTGELGPPQSADSEVIKRKAKILKGYVDACNITDGQTAVVRMA
SWAACLIAKEEGLDPIVQMTCRDRNRIALQMDVLGIAALGINNMLCLTGDHQKFGNHPTA
KGVYDLDSIQFVKMVRGMRDDKEFQCGEEMVVEPRIFIGAAANPFADPFEFRVARLAKKV
AAGADFIQTQIVYNVDKFAEWMKMVRDRGLHERVKILAGVAPIKSVGAARYMKTRVPGMD
VPDSVITQLQGVPKEQVPKEGIKLCIDIINQVREIEGVAGIHLMAIEWEEAVPEIVEAAG
LLPRPKFTP
>A0A535DBM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKARLKAAPRSRARSAVRHEHGPRRHAAPHSASIRWRCHHAMTKAAAIGGSPVAIGSRLR
RALDAGRSVITAELAVPATVAHKLILERAKGLLRPQIVAMNITDGLRGRPALSPIAAAAI
LTHADLGVEPIVQVVARSRARNALIADLLGASALGVRNLLCMTGDVPESSADIQDVDVFA
LIGLARGFPAGLGTELLGTAEPFCVGAAWSPFAPDPAHEAERLVRKHAAGAVFVQTQPMF
DAHGFAAAIDRLPVSLTELPIIIGLAPIRSCDHAQRLGAIPGIVIPDRLLALLDRASDEA
DACERYWAYLDAELDWLTRNVPHRGFHLMPIGHSKRGIRQSSSFDRLYAAATRALDAAPP
NLAEVAAPVEVSGRVFGTSAV
>A0A2E5DH81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNNQLLTNKFILTSELTPPKGVDLSKALNKAKSLPGINAFNVTDNHNSNMTMSPIGLAKL
LIENXIEPILQMTCRDRNILALQSDLLSANVLGVQNILCMSGESAKYGDHPEAKNVFDVN
SEQLISIVSKLNSGYDFNDNKLNQHTSFNIGAVFNPGATEIDKELLKLENKIKNGATFFQ
TQAIYETNNLDYINEIKKKHKIKIIAGFIPVKSVKMANFLNTKVPGITVPESIINTMDRS
SDPRNTCIEISKEIVTSIKESNIFDGVHIMALGWEDIIPKII
>A0A536ERL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
QLKVDSGADFLITQLFFDNRFYFDLVARARVAGIKVPIVPGLMPVPSRRSLAVMTAMSGA
TVPPDLQSAIDAAPDDDAIRALGVRHCIAQCAELLEAGVPGLHFYTFNRARAPIEILAAL
RGQQLLAS
>A0A1W9PHE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga sp. 4484_232|TrEMBL
MREALEKSKGVILEVLTPRGSNLRKFLEFTEKMWETGIDAFSVTDMPLGKVRMAPWAGAH
FLLERNMDVLMHFTRTTRNMIRIQSDLLGSYALGVKNLLILSGDDPKHGDYPNTTRVDDI
SITDLIKLAKSLNDGKDLGGRTIKPSTDFYVGAVFNHRDNTDLVKAKEKIRAGADFLISQ
PVFDVKEVENVIYELNEVKLVLSVVFFKSEKQFKIFSQVPGVNIPRKYLEDLENKSDEYI
RDYTLSKVLEIVDTLKSKVDGFYVVGIVRDSKVLEEYQRNFGTFLKKLGER
>A0A535UKN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSFLRSPRYEVLPTDDAADRVAANVPREITITVTASPRRGMPATVLLAVRLAQMGYRAV
PHLSARLIRDAHELGQILDALKEGGIDNVFVVAGDAPKPAGQFPDALSLLHALPAGHHLT
QIGVTGYPESHPFIHDDMTIQAMWDKRRLATYIVSNMSFDPATVSAWVERVRSRGVELPI
YIGMAGVADPVRLLRVSTKIGVADAARFLRGHPSWVARMFRPGGYEPGRFLATMLPDLAR
PKLGVAGLHVFTFNEVEPTERWRREMLARMEVVR
>A0A173Y6Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens|TrEMBL
MRVDEVFKQAASHGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDIPSVAHLTCMGRSRADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAAHQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A4V6X9Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CFBP13528|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLKNFVRKADAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A536ECN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSESDRPTTSAKGEPAAISTDGAGPAPAEPAMPEPAVEPLTFREKLEAGRFIVSVEVDPP
HGLGARKAIEGTRLLKEAGVDVINVGDSPTAKIRMSPLAMSTLLMREVGVEIVMHYTTRD
RNAMAIHSDMVGAHILGIRNILCLRGDPPSVGGYTDIVGVWDVSAVGLMRFLKLLNDGVD
FTGKSVGRQASFVIGGSANLNADPLEPELRLMRRKVEAGAHFFVTQNVFEEKKLEAFLDG
AAKFKKPVIVGVLPLANTRHAEFLHNEVPGMFLPDKVRERMRKAGEERGPKEGQAMARAT
IALCREKAAGVYLVPSFGRYELVAELVAEVQR
>A0A535X8C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRPYPRVIVHTPGPASDESGKLARDPRSRLQRSLDEGRSVITVELAVPATVAHEVVIERA
RALLRPQIVAVNITDGLRGRPALSSIAAAAIITHADLGVEPILQLTARSRPRNGLVADLL
GASALGVRNLNCMTGDVPENSTDLYDLDVFALIEMARAFPAGLGMELLGQADPFCVGAAW
SPFADDPAYELERLVRKRAAGAQFVQTQPVFDARALAAAVDRMPAALGDLPIIMGLAPVR
SSEHARRLTGIPGIVIPDRLLDLLDGATSEDDAAERYWAYLDGELEWLARNVSLRGCHLM
PIGHSKRSMRQQSTFDRLYACAIKITGPSASAAAAN
>A0A3N6F4X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ADI96-15|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRAAADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A396QNR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium OF09-33XD|TrEMBL
MYERTALSFEVFPPKTDKGMAKLPDTLDHLYKFNPDYISCTYGAGGSNVGKNMDVCKLIL
NAENETVPVTHFTCIGHTRETVKEQLQNYLDNGIDHMLALRGDLPYGWTGTNGDFAYATD
LVAYVRKEFGDKFEIAVAGSPEGHIECRSLEADIAHLKQKQDEGADYIMTQLTFDMEQFK
YWLDAIRMAGITMPVDVGVMPVVGKDAVINMCLSRNGCAIPRELAEVISHHWFDKDPDGN
DLPEVKAAFREEGIEYTVDQLHEYMSLGVEGIHLYALNKWEDVTEILNRAGIRTVV
>A0A5N0VIV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis acidicola|TrEMBL
MRDFLLSERNAPLLGAYVVPEPGEREAAIESAVDAGAAGADFVVTATSGPERSRYTSTNQ
SIDLAAAARNQAGIPALATVTTWSRTVMALQAHLLGGHARGITRLVCGNGSPPPAGDRSR
AEGRWAVDVVELIELLCALNEGKDRYGLRLDEATEFEIGVRLRAVPELSAEDRARIRRKI
EAGVHFVVTSPVYTVDALQPLLDVIDGEVPVFATVHHLRSAEEAEFLRNELPEGCLPEEL
LERLADAGEAAFEEGEKISADIVWPLASLTQGVILSRASRLVSRVRSELPRPAVS
>A0A535T4L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVRPLGGLGVGQALAEFLRTPRYEIFPTDDVLDLVAAYVPKEVTLAVTASPRRGLPATVQ
LAARLSQLGYRAVPHLSARLIRDRAELGQILEALKAANIQNVFVIAGDAREPAGQFPDSM
SLLEALPPDHGLTEIGVTGYPESHPFIHDDVTIQAMWDKRRLATYIVSNMSFDPATVKRW
VERVRHRGVELPIHIGMAGVADPARLLRLSTKIGVADAARFLRGHPSWLARMFRPGGYEP
GRFVSALLPELAQPDRRVGGLHVFTFNEIEPTERWRREMLTRLA
>A0A536I8R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARITDLLAAGRTFSFEFFPPKDAEEQQLLTRTIADLQPLRPSFVSVTYRGGRVSRERTT
RVVVDLLRTTELTPMPHLTCVAHPRSELGDIISVFRAAGLENLLALGGDPLPAEEQYKEL
EYASQLVDLGRSLGFRSIGVAAHPAGHPRSPDLTSDRRHLAFKMSLADFAITQFFFKVEE
YERLREDVAALGVAKPILAGIMPITSLTSVQRMAQLSGYAVPDDVVRRIEAGGDDRAEIR
RRG
>A0A1G9WFF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas antarctica|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISQMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0C6P938|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella bronchiseptica 253|TrEMBL
MTQSTAPAFSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRT
LRNLGCDAAPHLSCIGATRDQLRDILAAYREQGVRRLVALRGDLPSGMGGDAGELRYASD
LVAFIRQETGDWFHIEVAAYPEMHPQAESPSADLAHFVNKVQAGADAAITQYFFNPDAYF
DFVERAQAKGVAIPIVPGIMPITNHTQLVRFSEMCGAEIPRWIRLRLAEYGDDKASIRAF
GLDVVSELCQTLLENGAPGVHFYTLNHAEATLGIWKALNA
>A0A6N7X5Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parafannyhessea umbonata|TrEMBL
MRIADILKSKQTFSYEIFPPKGDMSVVQATDVAERLMQNSPDWISVTFSAGGSGNSQNTV
SVAKAIQASGKTQALAHLTCLGSSRADVDAYAEKIKAAGVQNVLALRGDRAPGRDVIDFE
HASDLVAYLKQAGLCVGAACYPEGHLESPSPEADIEHLKAKVDAGADFLVTQLFFDNEDF
YRFRERCSRARIKVPIVCGIMPFTSVQQIQRMAFTCGASIPAAVIKRLVAAGDSKQAQQD
AGVAYACEQLVDLARNGVDGLHVYTMNRPSVANATHDCLLQAGYVEA
>A0A7C1VNI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfofervidus auxilii|TrEMBL
MKAALSKGQFVVTAEFYPPKEANKNEVEKRALVLKDVVDAVLVRDNPLAQVHTSPIATAT
LLLNVGLAPIVQISIRDKNRLAIQSDILGASTLGVKAFFCLEDCHQRVGDNPGAKGVFDL
DCVQLISIMKKIEHSLVGTRINPFAHPLELHLVNLSKKINAGVDFIQTMPVFDLERFKEF
ISLIKG
>A0A7C6NFR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MRVCEIIEKADGPLFTFELLPPLKGETIDSIYEAIEVLLPYNPAYINVTNHQMETIYQER
EDGLLEPISVRKRPGTLGLSAAIQYKYGIDVVPHIICGGMTKEQVDDLLSELVFLEIDNV
LVLRGDPPAGVRRFVATPGGHEHSDSLVRQIAEKEWANFSIGVAGYPEKHIEAPNLEHDI
AMLKRKIEAGAHYIVTQMFFENSHYFSFVERCRSVGIEVPIIPGIKPLQRRRDLELLPQT
FNIELPSKLVDAVERSKTPQEIRDVGRSFCVEQVEELLEAGVPGVHFYTQGRSQVIADVV
EATYRERSTPIR
>R5KGU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:264|TrEMBL
MKLKEYIQTKRIIADGAFGTYYISLYGDGSRAENGAGLSNLPELANIKAPERVIGIHTEY
IEAGAQFVRTNTFASNTKSLSADMEKVKENICAAVMCAKMAAGKVDREIYLAGDIGPIPV
EGMLHSDRLTQEYIAIGETLLSQGIDILLFETFPELETILPAVTYLKENHDCTILVHFSV
NQFGYSNTGLSAKRLIAEANACPYIDGTGLNCGVGPGHMEKLIRKIAPDDTTFLSVFPNS
GYPKYLNNRLTFTDNAEYFTEKMEEIAALDVGIFGGCCGTTPEYIRRIAAGISADHPVRK
TETEAEKITVPEHPAYGFMERRVKEPAHKLIAVELVPPLNANDEKLLDAAHILKNAEVDV
VTFPDSPSGRTRADSVLMAEKIRLETGLCVMPHICCRDKNAIAIRSTILGASLNHITNFL
LLTGDPVPILFRQTTKSVFNFDSVGMMKIVQEMNSDTFTGHPVTYGGAINHNRMNTKAET
ERIRRKMAAGATFFMTQPIFSAEQADVIRQMKKETGATILVGLMPLVSRKNAVFMKNEMT
GIEIPDTVIERYREDMSREEGEACGVQIAREFMAMTDDFADGYYFSFPFNRVHMLKKILK
>A0A249SS69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sp. MD30|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPAFINVTYHRSEHMFKKK
TDGSFEKVEIRKRPGTVGICAAIMNHYNVDAVPHLICGGFSREETENALIDLNFLGVDNV
LVLRGDAPKNESSFEPDPNGHRYAIDLLNQVAHMNNGIYLEEDLQSGVKTKFCIGVAGYP
EKHFEAPNMQTDMGYLKRKVENGADYIVTQMFFDNQKFFDFVNKCREMGITVPIIPGLKP
MTSKKQLSVLPRTFHVDIPTDLSSEILKCKSDKEVEEVGTEWLIHQSKELKKFGVPVLHY
YTLGKPKVVEAAVAAFC
>A0A1L9QVM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseofilum reptotaenium AO1-A|TrEMBL
MVNSFRQALHSGEFLVTAEVMPPKGGDTSHMIEMSKHLKGRVHAVNITDGSRAVLRMCPL
AASVLLLQQGIEPICQVACRDRNRMGIQADLMGANALGIHNILALTGDPPKAGDYGDGRP
VFELESVRLLKVIDLLNQGFDAHQKKLPDGPLNLLAGAAVDPQLDSWSGLQRRFKRKLDA
GAQFFQSQMVTDFERLDKFMTQVAAGSDKPILAGIFLLKSAKNAKFVKRCVPGVHIPDSL
IERLANAEKPLLEGMKIAAEQIKLARNICHGVHLMAVKREDLIPQILDLADIGPLS
>A0A101AFS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. GA-1285|TrEMBL
MEFGPCGGVRPDGQCEMRSGACAFAEVVPWSGPRREPRPVPAPLVLTDFSCAPFDAHDVA
ATARLLAHSCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDRNRVVLEQELRG
LRSVGVDTALCVTGDGRGYDVRPDVTQTFDLDGPRLVELAASIGMVAAVPETPTAPPVSG
RPLRLVEKQRAGASVAVLNHVPFPAMIADFVQSARAAGLSIPVVAAVAVFTDNVSAAVLQ
GLPGLDLDPSVTDYVLGAADPVAAGIEAAVVEAKALLSIDGVDGVNVSGLASASGARVGA
EIKAEVGRRIREVAA
>A0A1Y2LUY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epicoccum nigrum|TrEMBL
MHISEKLARSRAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDVTWGAGGRHS
KLTTEMVKVAQTVYGLETLMHLTCTDMERSKLDEALNDAYQAGCTNILALRGDPPREREK
WEATQGGFRYAKDLVKYIRDRYGNHFDIGVAAYAEGCDDNDDVDLLIDHLKEKVDAGATF
VVTQMFYDTDIFLDWVKKVRAKGIDVPIVPGIMPIHTHAAFMRRANWTRCNVPREWSEAL
EPIKNDDVQVREVGCQLIADMCRRLIDADILHLHFYTMNLAQATRMVLEELELLPDVESP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGVGLKGTNEQNIKLWGTPTSVQDISDLFVRYMQGDLESLPWSEQPITEEANAIQKDLID
LNRRGFLTINSQPAVNGAKSSDPTFGWGPRNGYVYQKSYLEVLVSPEYIAEIITRIERDP
EFTYYAVNKTGDLKTNTPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQDW
ANCHASTSPARYVIGDVVDSWYLLNIVHNDFHVTNGIFPLFDGLKVEGMDKKLDSGITSD
APAINGHSATNGTNGTNGTNGTNGVQKDEKSLLETAKAAAVEVTNGMRNLAVSN
>K0XA30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Barnesiella intestinihominis YIT 11860|TrEMBL
MKVADLIKNSGSTGFSFEILPPLKGSSIEKSFKAIDTLREFAPLYINITTHRSELVYKDT
PDGLFRRVSERSRPGTVAVAAAIKNKYQIPTVPHLICSGFTALETEYALIDLNFLGICDL
LILRGDKAKHENRFIAASGGYEHAIELEQQVNRFNEGYFIDGTRMDLVSTRQFSYGVAGY
PEKHDESPNPDEDMKWLKAKVDAGADYIVTQMFFDNEKFFSFVDRCRAAGITVPIVPGLK
PISKASQLTLLPRVFHVDIPDMLVREIVKCKDDSQVKQVGIDWCTAQSLELKAKGVPSIH
YYSLMAVDSVYQVAKSVY
>A0A524IRS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MSIKENTDLKAEGLKAGSNLEKVLTAGKFAVTSELGPPKSADTAVIGEKARHLKGMVDAV
NITDNQTAIVRMSSIAAGVLAMQHGLEPVIQITCRDRNRIAMQSDILGAYALGLKNILCL
TGDHQKFGNHSASKNVYDMDSIQLIDMLKTMRDSKLFQCGEEIRNGKNAPISEPRVYIGA
AANPFGDPFEFRVIRLLKKFKAGADFVQTQCIYDMKRFEAWMKMVRERELHKKIKILAGI
TPLKSVGMAKYMRDSVAGLTVPDDYIERLSRVPKEKQADEGIAICVEQIKRFQDMEGIAG
IHLMAIEWEHRVPEIIERAGLLPRPAV
>A0A510JJ97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia hofstadii|TrEMBL
MKIKDMFEQKEHLISFEIFPPNKNFSQEKLKEVTAELVECKPDFISVTYGAGGQTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEIHDYLQEAKSKNVKNILALRGDIPQGETEDIYN
KGDYKYASELISDLRKNSEFDDFSIGGAFYPETHYENNDLVDLFHLKNKVEAGTDFLTSQ
MFFDNDIFIKFKEQAEKLDIKVPLVAGIMPVTNAKQIKRIIELSKCSVPHKLDKLLEKYG
DNPESMKKAGIMYASEQIIELLAYGIKGIHIYTMNKPEIAKEIMKNIEFAR
>A0A142YDX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomyces sp. SH-PL62|TrEMBL
MHILDIFDANPTTFSFEFFPPKTDKASADLFENIARLQELQPSFVSVTYGAGGSTRERTH
DLIVRIQQQTNITAVSHLTCVCHSEPELAAILDRYAESGIENILALRGDPPRNLEAYDPA
ADAFQYADQLVRFVRSRTTGDARGFGVGVAGFPEGHPGTPNRREEMDNLKRKVDAGADYI
CTQLFFGNDDFYDFRERCDLAGIRVPILAGIMPITSRETLMRIFELALGARVPAKLLRAV
DRCGDSNESIAKVGVHWATEQCRDLLDNQVRGLHFYTLNRSDATRRIYENLGVKDSLALA
SRKPA
>A0A016VHI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylostoma ceylanicum|TrEMBL
MDTPGGSVPNLHERSSSDEEHLSFEVGHGNKYVPLHERINRRIKDKTPFFSLEFFPPKTA
NGVANFFTRLDRFNEGGPLFVDITWHLGSDPANMNKETSSSSIAAGCLDYCRVDTMLHMT
CAQYSKEQTIKHLEQSKSVGLRNILALRGDLPNIDADGIPIYKYRALDMIRWIREEFGDY
FTIACSGSMTINAAIFTFLPQVDCYFTGYPLGHPESPSYKADLLYLKSKCDAGAQFIVTQ
LFFEAEVFEQFVRDCREMGITVPIIPGIMPIMGYDSIRRIATLSQLTIPESILSDLEPIK
HDDDAVRKYGTIKAIEMCRRILSNGSAPSIHLYTMNREGACREILQELGLWHKRPMRALP
WEPHGSNHPLRCKEDVRPIFWSARPKSYIYRTRDWDDFPNGRWGNSSSPAFGDLQDYYLF
HLKAQTKKEDLLKMYGEELLSFDDVKKVFTNFISQGVNENGVKVTTLPWNEQDVGVQAET
KLINEQLLWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFISKENAIS
LLEIVDDYYPRINYHIINHDGSFDHMNGEATTPIAVTWGVFPGAEIAQPTVVDPLAFRAW
KDEAYDTWIKNWANLYPKDSISRNVIQKIHDDFCLLNVVDNDFQKPVIIYEILEKMLKRT
EERKASA
>A0A7G9RBY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides mesophilus|TrEMBL
MALGLPSRMPGGAQTVRDLIAAGERSFSFEFFPPKDTEGERQLWRALRELEALNPTFVSV
TYGAGGTTRDRTVDITERIAHDTSMTPLAHLTCVGHSRDTLRSVIGSYAGAGVRNVLALR
GDPPAGPTAPFEPHPEGLHYAVELVEMLKSLGDFCVGVAAFPEAHPSAESLEADARVLVA
KARAGADFAITQLFFRPEDYFRLVDRVSALGVDIPIIPGIMPITNLAQITRMAELSGAAL
PAEIVERVGRFEGDPVAVRAEGIALATELCDTLLAGGAPGLHFYTLNRSKATRQIYAGLR
TTVAAGA
>A0A1C5M2N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKINELLKKRPTLSFEIFPPKNNENDITSIYATIDELAKMNPDFISVTYGANGSTSKNTC
KIASTIKNKYGIESVAHLTCMNNTKDEIKEILEELKENDIENVLSLRGDYPKDGDGINHG
DFKYASELNEFIEENFPNDFCLSGGCYPETHYEAINFEEDLLNLKKKVDAGAKYLVTQIF
YDNQYYYRLVREARKIGIHVPILAGIMPAHNPKQLKNIAKMSNCSVPFDLAAMIDRFAGN
PKAGREVGLHYATYQIIDLMTHGVDGIHIYTMNKPEIAKEILKRTEYIRDEFFKD
>A0A246GXZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. DrBHI1|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYQTAGIRRIVALRGDLPSGMGMASGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2A3AQN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM4313|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTKLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFADMGVKRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKNAGDFDISVSAYPEKHPESPDFATDIDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHETEAA
GSAAA
>A0A1Q8QB19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp. DV|TrEMBL
MEARRPFVSLEFFPPKEREAWEGFFGVVERLLPVRPLFVSVTYGAGGSTHAHTLEIVSRL
KTAYGLEPMAHLTCVGASRDKIRGFLDALRAAGVDNVLALRGDPPKGQEHFVPDSEDFQH
ASDLVAFIRQEYPELCVGVAGYPEVHPEAASPEADLERLGGKLALGGNFVVTQLFFDNDK
YFAFVDKARAAGITAPMVPGVLPVLSLASIKRFASLCGASLPPAYMAELEAADAAGGAAA
VAEIGIEYARRQARDLIARGAPGVHLYTLNKAEAVLSIVSGLDY
>A0A502JC86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas caspiana|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWKNLKLPR
>A0A0N1A851|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|beta proteobacterium AAP65|TrEMBL
MSTEHKSVPISFEFFPPNTPVGSDKLKTVVQELAAVRPEFFSVTYGAGGATREKTLATVK
DIAAMGHEAAPHLSCVGSTQESIREILGTYRAQGIRRLVALRGDLPSGTAVAGEFRYAAD
LIAFIRQEQGADWHIEAAAYPEYHPQQRYAKKDLEHFAAKMKAGADSAITQFFFNPDAYF
HFVDEVRKLGVTAPIVPGIMPIHNYAKIAQFAARDGIEIPRWVALKMEGYLDDAASVRSF
GIEVVARLCRRLIEGGAPGIHFYTLNQSALSLEVCKQLG
>A0A271JCY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivirga sp. SAORIC476|TrEMBL
MRVTDHYAAADEPLFSYEIIPPKRGSSVADVLGVVEALAPYDPPFIDVTSHSAEAIYDEQ
PDGTLRKRVKRKRPGTLGLCAAIQYRFGIDAVPHILCRGFTQEETEDALIELNYLGIHNL
LAVRGDDTGVAKLERPDRTRNEYACDLVGQIQAMNDGRYLADLLDAAPTDFCVGVGGYPE
KHVDAPNLTWDVLNLKRKVDAGADYVVSQMFFDNRHYLDWAARCREVGIDVPIVPGLKIL
TSKRQLQSLPRAFYTEIPEALAAEVEEAKDEHVPEIGIEWTRKQAEGLLEAGVPGIHFYI
MSTAKHVVRVAEPLRKLVG
>A0A1W9JHC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium ST_bin13|TrEMBL
MTISVSQLEEARRALEAPLFADLAGDANVSFEFFPPKTEKMEEALWETVKTLEPFGPRFV
SVTYGAGGSTRERTHATVARIQRDTSMGAAAHLTCVEASRDQIDAIADAYWQAGIRHIVA
LRGDAPGATGFVPHPQGYTNAADLVAGLKRLHPFEISVAAYPENHPDSRDSADDLDNLKR
KLDAGATRGITQFFFEPETFFRFRDRLSAAGISAEMVPGIMPVTNFASIVRMSAMCGTAV
PAWLGRLFDGLDDHPTSRQLIAATLAAELCRKLYAGGVRDLHFYTLNRAELSFAICHLLG
LRARVGERAAAA
>A0A2E4MAW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula sp|TrEMBL
MPGLADLYKSDSAVLSFEVFPPKTEKGEAVLFQHMEKLVDHKPAYMTCTYGAGGTTQSKT
LEITSRIKQQFNIPVASHLTCVGATIDQLRQYLTDAERQQIDYIVALRGDPPQGSETFEA
VEGGFHHANELVSLINHEFPHYGVAVAGYPEKHREAPSMEVDLQNLKHKVECGADIVITQ
LFYKNENFFQFREACQQAGIDVPIIPGLLPVTNLAQIQRITSLCGAELPESFVQRLSEKD
DPEWQFKVGVEQCSEQLDELLQAGIPGVHFYVLNKSQATSAVLDAVPLA
>A0A3M9Y2N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium nonalfalfae|TrEMBL
MHIKEMLADAERDGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIA
ELTCEMVTQAQSVYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREKEK
WVAADGGFEYARDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGATF
IVTQMFYDADNFVRWVGKVRERGITIPIVPGIMPIATYASFMRRAKHMNCSVPQEFMDAL
EPVKNDDNAVREVGKVLVAGMCRKILAAGIHHLHFYTMNLAQATRMVLEELNWMPTSERP
LKQALPWKQSLGLGRREEDVRPIFWKGRNKSYILRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNIKKWGEPQTVQDIATLFVRYLQNEIDCLPWSESPLTNEADPIREDLIA
LNKRGIITINSQPAVNGVKSSHAVHGWGPKNGYVYQKSYLEMLVHPDLYPEIISRIEKHP
DMTYYAVTKSGNLKYNAPSDGPNAVTWGVFPGKEIVQPTIVEGISFVAWKDEAFRLGLDW
AHCFEQSSPSRVLVELNNDFHQQREIFDLFEGLSVKEYDDIKPVAQDVAPDVVSAPTNGT
TNGIAVPAA
>A0A094QRW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSKLRDLLTQTKDVVYTAEFPVIDGGGMEQVKKNVDRLAPWFVAVNATDNTAAHAHASNV
SVAIAMKQHGLEPIMQIVCRDKNRLAVQADMAGANLHGIENIALLTGDDVTAGDEPETRR
VFDLDGPQAINVASILNAGTYLSGRKLNPAPNFFICSVENPFAPPHDYRIERALKKHRAG
AQMIQLQIGYHPDRLEKFCAGVAATVPDLAIIPSVVLIKSAKPLSFMNDKVPGISVPQDV
IDRVAQSADQAEAAYQLALEQAKHALTLPGVRGLHITDFRHDDTLERLMRDLGRTPNQYT
>A0A5C6XRY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lujinxingia vulgaris|TrEMBL
MSQIQMQSPFLKALAAGPVVFDGAIGTQLYERGIYINKSFDDANLSRPDLVAAVHAEYLS
AGAEVITTNTFSSNRIKLRRHGLEERAAEIASAGARIAREVAGDLALVAGSVGPTGRTPT
MLTEQELEEMRQAFREQITALAEGGVDVIVLETFRQLAEVRMALEAAREVCDLPVIAQMS
FDGERRTGDGADPERVAMLLADWGADVVGANCMEGPHVLYDVVVDMLSCGLPVSAQPNAG
YPRKVDERLVYMATPEYFGVYARRFFKAGVRLVGGCCGTGPEHIRQVSAAARMLGGGRAS
VEVSAARLPREEVEPELAKSQKAPTRLAEKIEAAHRSRAAGEPVSRENFVVSVEVNPPSG
LRADRAIEAARMLIEGGVDVINIADGPRASVRMANWALGRMLQESLDIEVILHLCGRDRN
LLGLQSDVLGFEALDLRNLVVITGDPPKVGDYPHATAVFDLDSVGILRMIDNFNRGVDPA
GKPVGDATAFYCACGAEPAAADYERELRRLELKKSAGARFVMTQPVYDPAVLDRFLADIE
YLDLPVLVGLLPLASARNAEFLHNEVPGMAVPLEVRERMRAAGTGQAARAEGVRIAQETL
EAVGSRVAGAYIMPPFGRYEAALEILSCLPGYATTPAIEEAR
>A0A0Q9ZVT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. P11G3|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALST
RGTTEIAPHMSCIGDDKSEIAELLEYYKTLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
YIREHSGDHFHIEVASYPEMHPQARSFEFDIDNLVNKYQAGANASITQFFYNADSYLYLR
DKLEKRGIDTVAQPLVAGIMPITNSSNLLRFADSCGADIPRYVRKQLTDFGDDRKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLTA
>A0A1F4D5D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_65_110|TrEMBL
MRHAGALAVLYRLFIRLAPRLRRSVEWLGPERLERVVAPAERTIKGFFFDCHMCGRCTLS
STGMACPMNCPKLHRNGPCGGVMADGGCELDPGMRCVWLEALDGAKRVVGRADLDPAQIQ
RPADQRLRGTSVWIGAIMARDTAAPESPSEGPAAPGQVREPGALERACRSGRFVVTAELS
PPDSADPQDLLRRAAPFRGQVDAVNVTDGAGGNCHMGSLAASALLAADGYEPVFQIACRD
RNRIAMQGDILGAAALGVRNLLAITGDGVENGDHPQARPVFDLDSVSLLEVARGLRDRGA
YASGRSIGARPGLFLGATINPFAPPFRERIANFEKKIAAGAQFVQTQYCFDPEMLEAFMQ
EVRARGIERRCHILVGVGPLASARTARWMLAHVPGVHIPAQLLHRLEQSADQRREGTMIC
VELIRAVRQMEGIAGVHVMAHRNESLVPEILRESGLAAERDAVPPRHGAT
>A0A7Y1VW36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospiraceae bacterium|TrEMBL
MKVTEHFAKAKGETLISFEVLPPLKGGKMKSIFDVLDPLMEFKPPFIDVTYHREEYIYQK
NPNGYYEKTSIRKRPGTVGICAAIMHRYGVDAVPHLICGGFTREDTENALIDLNFLNINN
VLAIRGDARQFDGRFIPEEGGHSYSVDLVKQIAAMNCGQYLDSNIENGAQTNFCIGIAGY
PEKHFESPNFKTDLRYTKAKIEAGADYIVTQMFFDNKCFFEYLQSCTEMGINVPIVPGLK
PLTKLYQLKSLPRMFYVNMPDELVREAEKIKNEKDATELGIEWCIAQSKELKAAGVPCLH
YYTMGDTDTIRRIVEAVY
>A0A5F0DMP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. MDB2-33-2|TrEMBL
MSTPTDSARTRRIPFSFELYPPKTDAAASALATTIDHLAAAGPDFLSVTYGANGSSRRSS
LDVLSRILRTTNVEAMAHLTCVGSTHDEANRLIREFLDAGVRSFLALRGDPPAGTKEGEA
FLGDFGSAAELVQLIHRVQAEKSPYRETIIPGIPAARAVKPGHEKVRIAVAAFPNGHPRS
RSSAQDIDTLLAKQAAGANLGITQLFFHADHFLSFVQRAREAGVLFPILPGIMPVTSPAR
LRRIIELSGEQMPADLSIRLEIEPTKEGQREIGIQHAVDLASQVIAGGAPGLHLYAFNQH
ETVLEVLDGCGLLGAPAPVRTPTALPTIV
>A0A2K0UBE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma harzianum|TrEMBL
MDKITEKIAALPADGEYFSLEFFPPKTAMGFSNLRVRLQRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREIGLTTCLHLTCTNMSQVLIDQALEDARALGIRNILALRGDPPRAEY
RDADEPDQAASEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPY
LVEKVQAGADFIMTQLFFDIEAYDKFETTLRSHPSGAFKTIPILPGLMPIQSYAMIKRTA
KLSHAKIPNETMTRLNAVKGDDEKVKMVGVDIVSELIGQIREIKSRTPGPKGFHFYTLNL
EKSISFILERTKLIPDVPEDEEAIVDEPVAAAAAQLVVPKISVNGNVPPRSSSHARTGRR
QSSVGSDPHNRVIVGRAATHPEWEATSTEAGIPAESVNTRANTLAISEGEGALGREATWD
DFPNGRFGDARSPAYGEIDGYGVSIHMSVTQAVRLWGHPKVASDINDIFVRHIRGEISAI
PWSEEDLLPESSIIKSKLEAMNRKGWWTVASQPAVNGLPSTDSTFGWGPASGFVFQKSFV
EFFLPSADWKILYDKLTSAEVEDVVCFYASNAKGDFVSSDGSGGSGQAVMSASTNAVTWG
VFPGKEIVTPTIIEEVSFRAWSEEAFDIWAEWAKVYGRGSDSQKLLDGIKEDRWLVNIIH
HDYVDTEALWRLLIE
>W7QAC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catenovulum agarivorans DS-2|TrEMBL
MNISFEVVPRTEEATLEQLRFVEENLPFVDTINIPDLLRLPIRSWDGAHLVNRNKYRYIP
HVRAIDFDLKSNRLQKIIEANELDKILLVTGDPPPDRTHLVYSTDVVDLIKAIRRDFPNI
EIYAGFDPYRYGVKQEKDYILDKFEAGADYILSQPFFDTRLLDIYADFLPADKVYWGVSP
VITERSQAYWENVNKVVFPSDFKPEYQWNIDFAVKVLKHCQQTGSHCYFMPIRIDLQKYF
LPIRQAINW
>A0A375H1X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus neocaledonicus|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILRQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVRAGADSAITQYFYNADAYFRFVD
DVRAQGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A2T3D535|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. NM-2|TrEMBL
MSPDYNPYDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNVMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHETLPTDALVASRMEHIREGKEENQQEMAEAAAH
HPH
>A0A3B7MVA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraflavitalea soli|TrEMBL
MKVIDHIRQANKPLISFEILPPLKGKTINSIFDHLDPLMEFKPSFINVTYHRSEHVFKKK
ADGTFDKVEVRKRPGTVGICAAIMNHYKVDAVPHLICGGFNKRETEDALIDLNFIGVDNV
LVLRGDAAKNETVFEPEPGGNRYALDLMKQVVNLNNGIYLEEDIRDGFRTKFCIGVAGYP
EKHFEAPNLQSDLDWLKAKVEAGAEYVVTQMFFDNQKYFDFVKRCREAGIEIPIIPGLKP
ITNKKQLSVIPRTFHVDIPTELSNEILKAKTDGDVEQVGSEWLLQQSKELKAANVPVLHY
YTLGKPKVIYNAVKELV
>A0A1F3N0Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium RBG_19FT_COMBO_42_10|TrEMBL
MSVIDKIKNSRRPLFTFELLPPLKGHSIDRVYTAIDRLIEFEPAYINFTTHRNEITYKER
TDGLLEKRVTRLRPGTIALAAAVKYKYNITVVPHILCGGFTREETENVLIEMNFLGIDDV
LALRGDPQRGSRSFIPEKDGHTHTYELVKQIVNMNKGRYLEESLVDTISTNFCVGVAGYP
EKHFEAPNIHTDMENLKNKVESGASYIVTQMFFDNSKFFRFRDECKKMEINVPVIAGLKP
ISTLNDIKLLPQTFHIDVPGDLVSAIKRCSTDKEAREVGIEWATMQSRELIKEGVPGIHY
YTLGRSDNIARIVKAAF
>A0A257Y3Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium 12-64-8|TrEMBL
MSVPHENGENYELVSHPRICDEGVQQETAMPVPALAPLQPDFVSVTYGAGGTTQGLTRDA
VTTLQRTTGLTVAAHLTCVGATKAETLAVAEAYHAAGVTQIVALRGDAPVGAERFAPHPD
GFASSVELVAALARTGRFTIRVGAYPEPHPDAADPAADVTWLKRKIDAGATSAITQFFFD
ADTFLRFRDACAKAGITAPIIPGILPITSWAGAKRFAQRCGASVPPRLDEAFATATRDGR
EELLALTHCTALCDRLVQAGVQDLHFYTLNRPHLTREVLRALGVTTEVQLEKVA
>A0A259DA73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium 17-64-5|TrEMBL
MPHPDGFASSVELVEALAKTGRFTIRVGAYPEPHPDAADSAADVTWLKRKIDAGATSAIT
QFFFDADTFLRFRDACAKAGITAPIIPGILPITSWAGAKRFAQRCGATVPPRLDEAFATA
TRDGREELLALTHCTALCDRLVQAGVQDLHFYTLNRPHLTREVLRALGVTTEVQLEKVA
>A0A7C1UF48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MKSQGHYDKVFSFEFFPPKTDDGVEKLNATREKLAALKPKFFSVTFGAGGSTRDRTYDAV
KAIQQAGHQAAPHISCIASSKDSVRKLLSKYQALGIKHLVTLRGDIPSGMGGTPGEFQYA
SELVAFIRTETGDHFHIEVAAYPEFHPQAASAQSDLEYFKRKVEAGANAALTQYFYNPDA
YFSFVESCEKMGLALPIVPGIMPITNCTQLTRFSDACGAEIPRWIRQRLEGFGDDMDSLR
AFGMDVTTGLCEKLLDGGAPGLHFYAMNRSEPSTEIWKRLGLS
>A0A1W9M7C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium A2|TrEMBL
MKQDFLATLAERVLLGDGAMGTYLYAKGVERGQVIERLNLSEPDLVYGVHEEYIRAGSQL
IETNTFGANRFRLQLGAEQVREINRVGATLARRAAGSGVYVAGSVGPSGIEFPLEHGEIG
AGDVKEAFAEQIGGLLEGGIDVLQLETFGSLDEMLLALTVARRLCDLPIISQMVYPAGGR
TPDGVEALTCARAALAGGANVVGSNCGRGVQPMLVALEQLGALRGIAPLSAFANAGFPEV
VGHRLVYPADPAYMARMLKEAVRLGVRLVGGCCGTTPVHIQELQHLLHVKKRTVAVLEPA
APTETSPEAEARPRGPGALLRGLADGSGLPLVVELDPPTHLDLAGVLEGARALAGAGVDV
ISLAENPLAILRSDNLSLAHRIRQEQQLPVILHLTCRDRNVLGLQNQIMSAHHLGLDSIL
AITGDPAASSDQPGVSGVFDVQSFGLVRMISQFNQGRNFAGKDLRGHTDFSIGVAFSYRP
QRPETQLSRLEKKAALGAHYAMTQPFFDADEVEQMMEQAARINLPIFPGIFPLISARNAE
FLHNELPGISIPAWIRERLGSFEQVEDQRKAAMEITRGLIEKMATFVDGLYLISPLNKWQ
ITAQLAGEIRLAGWRGSGRLRQK
>A0A1Q8B1Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_20CM_2_55_15|TrEMBL
MQDLLTRLENHVLVCDGAMGTMLYSKGVFISRCFDELNISNPELVREVHLDYIKAGADII
ETNTFGANRTKLMTHGLADQIRHINIQGARIAGDIAGDNILVAGAIGPLGIRIEPWGKTA
IEEAQVTFREQAKALVDGGVHALILETFFDLNEVYAAIRGVRDVTDQPLIVQMSIEEDGN
SLEGTPPEVFAKRLEEWGADVLGLNCSVGPQIMLDAIERIANVTSKKLSVQPNAGKPRNV
EGRNIYLGSPEYMASYAKKFVQYGVRIVGGCCGTTPQHIKAIRAAVKSVGVAVLGPSPGA
SRRPLPAGEGTEGESSIPLESRSRLGRKLATKEFIKIVEMIPPIGHDFAKAIEKAKYLQA
QDVDAINVPDAPPSSARMSAISLAVLLEKSTEIESLAHYTCRDKNLLGMQSDLLGAYALG
LRNLLLITGDPHQIGEHSDATAIYEVDSIGLTNMVSRLNGGVDVGGKSIGKPTGFVIGVG
ANPGAMSDLELKRFFYKVEAGAEFVLTQPVFDATVLERFLDRAGNSKIPVIAAIVPLPNY
KTAEFLNYEIPGCSIPDSILERMREAQSKSPEHARNEGILIAQEILERIHGTVQGVQIRG
PFDRYETPVEVLSVPMKGATR
>A0A7K0EZB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aequorivita lutea|TrEMBL
MKVTEHIKNGNGKTQFSFEILPPLKGENIHSIFENIDPLMEFQPPYINVTYHREEYVFKE
LKNGLIEKKIVRKRPGTVGICAAIQNKYEVDAVPHILCGGFTKEETENFLIDLQFLGIDN
VMALRGDAVKSETYFSPEKNGHKYACDLVSQINALNKGTYLDDELQHTFPTDFCVGVAGY
PEKHMEAPSSESDIHFLKKKIKNGAEYIVTQMFFDNEKYFKFVEKCRAEGITVPIIPGLK
PIAVKSHLNLIPHRFKVDLPDSLVMEVVKAKDNKAVRQIGIDWCVKQSKELVKAGVPFLH
YYSMGKSSNIREIASQVF
>A0A7N2RCN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Quercus lobata|TrEMBL
MKVIEKIQEAGEEKVVFSFEFFPPKTEDAVDNLFERMERMVAHNPTFCDITWGAGGSTAD
LTLDIANRMQNMICVESMMHLTCTNMPVEKIDHALQTIKVNGLQNVLALRGDPPKGQDKF
VQIEGGFACALDLVKHIRAQYGDYFGITVAGYPEAHPDAIGENGLATLEAYHKDLAYLKQ
KVDAGADVIITQLFYDTDIYLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKI
PAEIMAALGPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEETKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCNPS
YGALSDYQFMRPRARDKKLLEEWATPLTNVDDIQEKFKKYCLGKLRSSPWSELDGLQPET
RIINEQLGKINTKGFLTVNSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSREKLDA
LVDKSKAFSSLTYMAVNKEGNWISNVHQTAVNAVTWGVFPAKEIIQPTVVDPASFMVWKD
EAFEIWSRGWASLFPEGDPSRKLLEEVQSSYYLVSLVDNDYIHGDLFAVFADF
>A0A0B5BEF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter pickeringii|TrEMBL
MTFIERLKSEVLVGDGAIGTMLYAKGVPLDANVEHLNLVRPELVLELHREYLTAGARVIE
TNTFGANGTKLAAIGLEKREREINLRGAELARRAAAGYDAFVAGSVGPLVRLKGEERELS
AAETTEIYRRQAGALAEGGVDLLILETFTDLSPLICALVAARETGLPVVANMAFLEQGRI
AGGLDVERVALELAAGGADVIGANCGAGPLEILGTVRRMARVTDRPLAAYPNSGFPEYVN
GRHVYRTTPDYFAERAVEMVEAGAALVGGCCGTTPEHIRRLAERLGGMRPAVRQVVVPEL
PAEERREAAAVAEGFLARWGKEPVVTVELDPPKGFDCDKIIAGSRVLKAAGADAINIAEN
PLARIRMGNIALGHLVQREAGIEVIVHVTCRDRNLLGLQSDLMGASLLGIRSILAVTGDP
ARIGEQAGASSVYDLNSFTLIKLLADLNAGVNALGNPLGRGAGFTIGCAFNPNGQRMEVQ
AGRLEKKVANGARFVQTQPIYDLARLDGMLEQTAHLDIPILPGIMPLVSERNCEFLHNEV
PGIVIPDEIRQRMRGKEKDEGVREGLAIAREFIDAARGRVGGFYLVPPFGRYEIAAELVR
YIKEK
>A0A182UDN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles melas|TrEMBL
MSVTSEPNNTMATTNTVTNEEESNEDSLHTKLNRIFNSSITTGPVPVHYSIEIAAKDDFD
IGQLKRLTPQPVFCALPWVSDDNLRYADDFLRSPTLQLTARLRENQYTVLNNVSCYNITE
QRVDQLLHSTGIRNLFVIRGDTVSPGQQFRNSAGLVQYLRKWQEQQPDHRQLTIAVGGYP
YGHHQSSSQTEELHYLRAKISQGADFLLTQTLYDAPSFLRYRDRCREAGITIPIIPGIYV
PHSYRHLQALLNLTRIELGPTVRDAFEAHANDAPDQFQSFMVEYFVGVVRELLQPNATTS
SDPIKMVHFFTFNKFHLLQQVLEKLDEFFQ
>A0A346DX57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter pomorum|TrEMBL
MSLSRLSVELIPRSAEALAADVATVKTTFPAADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQSGLEEILIVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMQGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLEANILFAQTVLKELAQEKGKAYLMPVRIKLEQY
LPALLDAVA
>A0A3M3FCY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. atrofaciens|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRKLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A2S6RXM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha9_Bin6|TrEMBL
MSGAGVKSLRKLGHKDRAALEVSFEFFPPKTEKTVERLWRSVDRLAPLRPRFVSVTYGAG
GSTRDRTHAIVAHLRRNTDLEPAAHLTCVGASVEEVNAVVRDYYAAGVRHIVALRGDPPE
GESKFTPHPEGYDGSVELISGLKTIADFEISVGAYPEPHPDSRGMQSELDYLKRKLDAGA
TRFITQFFFDNDCFLRFLDKVRGAGIEAPIVPGILPVTNFQQVARFSSMCGASIPDWFGS
RFDGLDDDPSTRQLVAAHTAADQCFGLLESGINEFHFYTLNRADLVFAICHMLGVRAGPT
DATGAD
>A0A1M7G0T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium polytrichastri|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYRNIDPLMEFNPPFIDVTTSREEYIYID
KGNGLMERKITRMRPGTLGICSAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEATKGGHESAMDLVHQINDLGRGKYLHDEQACEENNKFCIGVAGY
PEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVTKAREMGITIPIIPGIK
PIATKRHLKLLPQVFKIDLPEELINEVESAKNNEAVRQIGIEWAINQCRELLDFGVPVLH
FYSMGKSDNIKKVAGELF
>A0A528LW77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNDRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDL
>A0A2E8ME80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MSSLSQALASDEFVVTSELTPPKGTDLSTLLNKAEKLKSHVTAINLTECHTARMAMDPVA
AGHLMLDRGIEPIVQMTCRDKNRLAIQASVLGAAALGVSNIVFMGGDPPKNGDHPEAKPV
FDLYSAQLLEAAHALASGTDLMGNALSGTPTLFAGAVTNPGAADLDAEIDNLQRKAAAGA
CFFQTQAVYDAEAFAAFLEKTRLEQPMLAGIIPIKSVKMANYMNERIPGVEIPDALIARI
ADAGDDPKRVAQISIDIAAETVRKLRPIARGVHLMAIGWEKHIPEILARAGV
>A0A531JRS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
INPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILCGVG
PLASAKTAKWIRSNVPGIHIPDQIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSGVHV
MA
>A0A4P8X2R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. PCC 11901|TrEMBL
MTTRLRRAIENRDFVVTAEVAPPKGGDPTKMLRMAKLLGDRVHGVNVTDGSRAVMRMSSI
AASTLLLQNGIDPIFQVACRDRNVIGLQADLMGAHALGLRNVLALTGDPVKAGDHPKAKA
VFDLESVRLLKLITKLNNGQDFNDKKMPDGSLDLFPGGAVDPQLKSWYTIESRFARKVES
GAQFFQSQMITDFQRLEEFMNRVASQYDVPVFAGIFLLKSAKNAQFINRCVPGAQIPDAI
IERLAQAENPLEEGLKIAAEQVKIAKNLCHGVHMMAVKKEDLIPQILDLADVSIQISTAP
ALV
>A0A346DTV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter pomorum|TrEMBL
MTGILSTWLSEKRIDRLLSCNSETPILSFEFVPPRTDAMEQRLWHCIWRLAPLAPRFVSI
TYGAGGTTQVGTLSTVLRLKRNTDLISAAHLTCVGAPREAVDDLARCYRDAGVHHIVALR
GDPSAGAVDDSPRPGGYTYASDLVAGLRRIADFDISVAAYPETHPTALSPEADLDNLKRK
LDAGATRAITQYFFDSEIYLWFLDRCLAAGITAPIIPGIMPVSNYEQIVRFSAVCGVTVP
AWLRHLFDGTAKNPELRRIVASMVAVEQIRTLQTYGINEFHVSTLNRADLTYAIAHILGV
RPMQTNASHNVTGLLEKTEVPDERETPADFDSTAWAQEGAPPFMLRTLFG
>J7MPV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polytomella sp. Pringsheim 198.80|TrEMBL
MKIIDKINLKIEERRPFFSFEFFPPRTEEGVENLFERQERLVSYGPVFCDITWGAGGSTA
DVTQDIAVKMQNLVGVETMMHLTCTNMPKERLEIALKEVQKAGVKNILALRGDAPKGQDK
FEAIEGGFSCALDLVKYIKKEFGSYFGIGVAGYPEAHPDSIVDDPEQMKKNYFENIEYLK
KKVDAGADFIITQLFYDANIFIKFMNDCRAAGITCPILPGIMPIASYAGFKRMTSFCKTH
VPQHILDAVEAIKDDEEAIKNFGISYGVEMCRKVLAAGAPGVHLYTLNLERSAVGIVEKL
GIMPEQLGSRFPLPWRPASIGTDRTNEGVRPIFWANRPKSYVLRTSHWTEFPSKSWTSKL
LASAAFDSSVDQKPLSDAVNVATVTEASLASHVIGDVNKYQMTRHICSTLRQERSRASWG
IEVSNVEAVKDVFAKFYLGELRGLPWFEHDVPGAAAASIELREQLAVLCRKGILVMNCQP
SARETPATDPVVGWGPTKGYVYQKAYLEFFVAPEAFRSLLPVLQGKENVTYMASDVRGEI
FHSNAAPGDVNAVTWGVFPGHELVQPFVATLPAFLSWRDEAFALWDEDWAALYPEGSVSR
TVLKAIHDTYVLVSITENDFVNGDLLSKF
>A0A529ZVV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MSARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLET
>A0A1C5M8J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Dorea sp|TrEMBL
MTCKIRDILKDQTPQVSFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKN
TVSIASHIKDDFGVTSLAHLTCVSSTREEVHQVIDKLKEKNIDNILALRGDIPKDNAFPL
PNQYRYACELIEDIKQQGDFCIGAACYPEGHVETEHKKDDISNLKTKVGCGVDFLTTQMF
FDNNIFYNFLYRIREKGILVPVLPGIMPITNKKQLRRSMELSGTAVPQRFLAIIDRFGDD
PEAMKQAGIAYATDQIIDLIANGINHIHVYSMNKPDVAAAIMNNLSAILKVED
>A0A1Z2LG64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. WZN-1|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAARLKGYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRRMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A412ARX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF28-5AC|TrEMBL
MRVDEVFKQAASQGTAPISFEMFPPKGELTLDMAREVAGNLCKLSPSFVSVTCSAGGSGN
GAATAPIAHMITSEFDTPSVAHLTCVGRSHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNVSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A531AJ79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVNAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AHRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDN
>A0A2E8MG90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MHLDDQAVPSTALSVQPGYSSSGRLERVLRAGSFAVTTEIAPPDSADSAEVYRRAGIFDG
WVDAINATDGSGAXCHMSSVGVCSLLTRKGYATVMQVSCRDRNRIAIQGDVLGAAAMGVS
SILCLTGDGVQAGDQPDAKPVFDFDCMSLLQTVAAMRDRSELMSGRPLTVPPKVFIGAAA
NPFAPPLDYRPLRLQKKIEAGAQFVQTQYCFDLXRLTXYMRQARDLGLDXRCFILVGVGP
LASARTAAWXRDNVPGVHIPDAIIKRLLEANDQKEEGIRICVEMIQAIREIEGVHGVHVM
AYRQEHRIPDIIGASGVLAGRVPWYPGCTEISPQXRTVT
>A0A1I2DPV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. DSM 26671|TrEMBL
MTLVSERQAFNRPDEEAAARFRDLVRSASIEATPRQILTTEHLPDLLPAGTCVYVPFLPK
GQFSDTLEASRRLLDLGMQPVPHVPARMAQSRGQLRDWLAQLDESGVDRLLLIAGDSDAV
AGPFPDTLAVLESGLLAQFRFHGIGVAAHPDGHPMADRATLAQALSVKREYARTTATRLW
VVTQFTFDAEVVIDWLQGLGNILEEVPVYIGMAGPTRVKTLIAYAAMCGVGASARMLLRR
PGSARMLGAWKPDDMVRALVQYCLENPETLLRGIHLFPFGGLRQSAQWIRDHSGSCENNR
EAVP
>A0A531KH57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
KGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRAITQFFFDNDLYERYVERAR
RAGIYIPIVPGILPIHNFTQVGNFSARCGTLVPAWLAERFDGLQADPQTHALVASAVAAE
QVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAAGSAAA
>A0A2E1WKS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MTPVTGDPGQPLAILEGHVSAGRLERVLRSGKFAVTAEIAPPDAADAEAVYERASVFDGC
VDAINATDGSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVTN
ILCLTGDGVQAGDQPDAKPVFDFDCISLLQTVTAMRDEGEFLSGRKLTTPPRVFLGAAAN
PFGPPLDYRPIRLEKKINAGAQFVQTQYCFDLVRLREYMSRVRDMGLTERCYILVGVGPM
PSARTASWIRDNVPGVHIPDAVIKRLLGAENQKEEGVRICVEMIQAVREIEGVHGVHIMA
YKQEERVRDIVEESGVLEGRIPWYPGVSNDQQGQQT
>A0A8J3BJT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pilimelia terevasa|TrEMBL
MSLGLPSVLDDSQPSIGALISASAPTFSFEFFPPRTAEGERQLWSAIRELEPLRPSFVSI
TYGAGGSNRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRHMVGRLADVGVRNVLAVR
GDPPGDPTGEWVRHPAGVTYAADLVRLIRTAGDYCVGVAAFPYKHPRSPDIESDTRHFVA
KCRAGADFAITQMFFDADDYLRLRDRVAAAGGDTPIVAGVMPVTSMRTIARAPQLSGAPF
PAALRERFDRLADDPVAVRRLGVELAGEMCRRLLDEGVPGIHFITLNRSTATREVWADLG
VVAGA
>A0A7C7LUV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEKIANYKAQGKTFYSFEFFPPKTDFGLDNLYSRIDRMASFQPAYIDITWGAGGSTA
DKTLGMCKTIQKYFGLEVMMHLTCTNMPVSSIKKVLTEAKENGLSNILALRGDPPDGSSS
WKQHENGFRCGADLVRYIRKGFGNYFFLGVGGYPDGHHEQSDLDIDISFLKEKVDAGSDI
VVTQLFYDVDKFLFFRDKCIKSNIKVPIIPGIMPIHNYARFLKFTQFCQVSIPDSVSTQL
ESIKNDDSSVINYGIDQAAAMCQKLIENGVPGLHFYTLNLEHSVSAILKSLGFVSSRSTI
RELPWRQSASDDRKTSEDVRPIYWSNRPVSYLTRTENWDDFPNGRWGDIASPSFGELNQY
HAIRAGSKSDKVKARRKKMWGEPKSIKDITDVFVSFCKGKINSLPWCEIPLAIESQQISS
DLINFNELGFFTINSQPKVNGAPSEDVEVGWGGPGGRVYQKAYLEFFTSRDKLDGLLKSM
ESTDNISYQAINVDGDLITNLLENSVMAVTWGIFPGKEVIQPTIVDARSFLIWKDEAFSL
WMDDWASIYKAKSESYEIIKEIYDTYYLVNVVDNDYVAGNMLQQILKS
>A0A854B8G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7Z9N7E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEKIADYIAEEKTFYSFEFFPPKTDFGMDNLYSRIDRMASLHPAYIDVTWGAGGSTA
DKTLEICKTIQKYFGLEVMMHLTCTNMAVSSIKKILTEAKESSLFNILALRGDPPEGSLT
WEKHADGFRNGVDLVRYIRKEFGNDFFLGVGGYPDGHQEQTDIDIDINFLKEKVDAGSDI
VVTQLFYDVDKFLLFRDKCIKAGIKVPIIPGIMPIHNYGRFLKFTQFCELSIPDLVSTQL
ESIKNDDSSVINFGIDQATTMCKKLIEEGVPGLHFYTLNLEHSVSEILKSLDLVSSRGIS
KELPWRQSTLGDRKTSEDVRPIYWSNRPVSYLTRTESWDDFPNGRWGDITSPTFGELNQY
HAIRAGAKSDKVKARRKKIWGEPKSIKDIKDVFVSFCKGKINSLPWCEMQLAQESQQISS
NLINLNEMGFFTINSQPNVNGAPSEDAVVGWGGAGGRVYQKAYLEFFTSKDKLNALLKSI
KSTENISYQAINIDGDLITNLPENSVMAVTWGVFPGKEIMQPTIVDTRSFLIWKDEAFGL
WMSDWASIYEKKSASFKLLKEIYETYYLVNIVDNNYVDSNLLKKLLNHEKA
>A0A7V8FR97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax wautersii|TrEMBL
MTFPISLEFFPPKTAEGAEKLRGVRQQLYALQPEFCSVTYGAGGSTQQGTFETVSQILAE
GVDAASHFSCIGATRQGVAEQLATLKRMGVKRLVALRGDLPSGYGTGGEFQYASDLVAFI
RETTGHDFHVEVACYPEIHPQARSAEADLKALATKVQAGADSAITQYFFNADAYFRLVDD
AGRLGVAVPVVPGIMPITGSSQLMRFSDACGAEIPRWIRLRLQGFGDDAASIRAFGLDVV
TELCERLRAGGAPALHFYTMNQSAAVLEICKRLGLAKAV
>A0A1B3DI74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYQQAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7Z3H1U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVTEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A3G5TBB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium YIM 96077|TrEMBL
MSLGLPTTTPENGTTIRELLAAGERSYSFEFFAPKSEQAEELFWRTIRELERLRPTFISV
TYGAGGTSRESTVRVTGQVATDTTLTAMGHLTAVNHSVAELRHVIGSYADAGIRNILALR
GDPPGNPQGEWVPHPEGLNYSEELVRLIKSVGDFCVGVAAFPEKHPRSPDLQTDVDFLVR
KFRAGADFAITQMFFNVEDYLRLRDRVAAAGEDKPIIAGIMPVTNVKQIERFAELSGAEF
PEWLAKRLRAVQDDPEAVRAIGVEVATEMSERLLEEGAPGLHFITLNKSTATREIYQNLG
LGASLVPA
>A0A0Q5NI34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Leaf337|TrEMBL
MSPPSLIDTHPNLSDTAPVALSYELFPPRSPAAAASLWTTIGELEATDPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPEELSEIIGELLDVGVRGILALRGDQPKD
GGTPASGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPTEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLITRARRAGVTIPIIPGVMPLTSVRRLNRLGELTGVE
PAPELMARLAAADNDAERRLIGVRATVDLANAALDAGAPGIHLYTFNEHACALEVLDKLA
LPRPARPASRLNAIARRHQEMAS
>A0A2A5RHC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVTEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A2D5Q091|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
LIENGVPGLHFYTLNLEHSVSAILKSLGFVSSPGTIKELPWRQSTSDDRKTSEDVRPIYW
SNRPVSYLTRTEIWDDFPNGRWGDIESPTFGELNQYHAIRAGSKSDKIKAKRKRMWGEPK
SIKDITDVFVSFCKAKINSLPWCEIPLALESKLISEDLLKLNEMGYFTINSQPKINGVPS
EDAEVGWGGSGGRIYQKAYLEFFTSKDKLDKLLKSIGSKENISYQAINISGDLITNLPEN
NVTAVTWGVFPDKEIMQPTIVDTRSFLIWKDEAFSLWMNDWASIYEAKSESYELIKEIYD
TYYLVNVVDNDFVDGDILKQIVKS
>A0A1H9Y3R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. kh1p2|TrEMBL
MNVAELLNRNKDQRNFSFELLPPLKGSGTDKLFATIEKLKEFGPLYINITTHHSEYVYRQ
LDNGQFERLRIRRRPGTIAIAAAIQQRYDLPVIPHVICSGTTVEQTEYELLDLQFLGISN
LLLLRGDKARDDRSFTPTEGGHAHTTDLIAQVNRFNEGFFADGSPIKCPGTPFGYGVACY
PEKHEEAPNLEMDMKYLRQKQDMGAQYAVTQLFYDNRKYFSFVDKARQMGITIPIIPGIK
PLAKLSQLTTVPKTFHCDFPQELASEIVKCTTDEQARQLGIEWTTHQCRELYAHGVNNIH
FYTVSAVDSVREVVRRLQ
>A0A4Y9TD33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYQPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEEDLKNFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1F9AK84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_52_11b|TrEMBL
MKTKSNIERILESGGFVVTSECGPPRGADPEVIRRKGGLLKGVIDAVNVTDNQTSVVRMS
SLSSCIILKELGFDPILQMVCRDRNRIAIQSEILGGAALGINNILCLTGDHQKFGDHPKA
KNVFDMDSIQLIQTVKGMRDEGKFLGGEEVKGKPVLFIGAAENPFADPFEIRAARLGKKV
KAGVEFIQTQCVYNIARFEKWMEMVRDRGLHERCAILAGVTPFKSVGMARYMKNSVPGMD
VPDEMIERLKGVPKEKQSEEGIKICVETIQKLKEIPGVRGIHIMAIEWEEKVPEIAKAAG
LLPRPVPST
>A0A2N3QL46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium thermophilum|TrEMBL
MHQPMFSIEVFPPKRNAPVGTIYDTLDGLQGLNPDFISVTYGTGKSSDRTATARIANTIR
KEYDIPAVAHLTAQYTTREQVDEALDMFRQAGVSAVLALRGDPVPDREPAGAFEHASDLV
AYIREHDPDMTIFGACYPECHPQASDLDEDIRNLKIKVDAGASHLISQLFYDNADFYHFL
DKARAAGIDVPIEAGIMPVTNAKQIRRMVRMCSSRVPLPLESLLDKWSDDPKTLKQAGII
YASNQIADLVAHGVDGVHLYSMNKPAVTRQIWHNIEDLFSPGQTGTDFA
>A0A2E5GDR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIRDKIKRPRRPVVFYEILPPREKDGTLNSYAETISSLLSQTHIDAINIPEVREEEGFG
KKPVKSLTRAEPREFGQLLQDIVGVEAVVNRVIVHQILEEELNWVDETNNKYEIENLIIV
GGESHKINYPGPTVNEALNSITSPNNSRIEDILCGGISIPSRNAESKNLIKKIDNGAEFF
TTQVLYDSEKIMKMISHYQDRCRKLNTFPRRLLLSFAPVSSQKNIDFLKWLGVEIPEDTE
KYLNGRPGSMIDRSLDVAIEILNNTLSHIIKNKLVVPIGLNVEHIMSYNFQSSVEMLQEL
ARIYREFCIKADFYV
>A0A2R4BNU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera aromatica K172|TrEMBL
MYSVRLWSVRNARALHRLYTFFSRLAPRLAPLVHRVGERRAEVLLRPLERSAKNVLFDCR
MCGQCVLSSTGMACPMNCAKQMRNGPCGGVRADGQCEVEPGMRCVWVEATEGTKRIAADH
LAHPTPLLPAIDQRRRGRSTWIEVVHGRPAPVFQPPVGERITPESEQSLFERSCAAGRPV
VTVEIAPPDSADPAALLARAELFRGLVDAMNITDGAGGNCHMSSVAASAILATHGFEPVY
QIACRDRNRIAIQGDLLGAAALGVKNILCLTGDDVSRGDHPQAKPVFDLDAVSLLHVARG
MCDRAEFASGRKLEQAPDLFIGATVNPFVPPYVDRVANLEKKIRAGARFIQTQFCFDVER
FADFMAEVRRRGLHRQAHILVGVGTLGSAKALRWMANNVPGVFIPEALLARIEAAPDQKA
EAKQACIEIIRAVTAIEGVAGVHLMGHRNEAVLARIIVDAGLRAPPPAVDEADPGAAPAS
SRLAAA
>A0A165ZLH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A2E4AIM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKIIDYFNNSDKTLFSYEIIPPFRGGSLQKVFELVEQLMPFNPPFIDLTSRSAESYYQDD
GSGQLSQHIRRKRPGTIGISAAIKNKFNIETVPHILCNGFTKEETEDALIELNYLGINNV
LAVRGDELRTNPIDDKKNRNKYASDLVTQIYEMNSGKYLEPLIDPFKTNFCIGVGGYPEK
HFEANDMNTDIKKLKQKVDNGADYIVTQMFYDNKAYFKFVEMCKKEGIDKPIIPGIKILS
TESHLTMLPKHFHINLPSELISAVEGKSKTEIRNAGINWAVKQVNELIEAKVPCVHFYIM
TSAKSAIQVVSEFI
>A0A193CXP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar coreanensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDENAILGTIGGMKHIGAVTTTDMERE
FILLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSIGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1I4I0K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. 1_12|TrEMBL
MKLDLREALHQDILVGDGAMGTFLYQMGFPVGISYEELNLLKPEVIADVHRRYYEAGARV
IETNTFSANREKLSKFGLEQEVEAINRAGVEIARKAVGSDAYVVGAMGSIRAGKRKNVRT
TKLKDDLRQQIEVLLDTQVDGLLLESFLDLEEMLLALKIIRKLSNIPVICQFATEGSGTT
EDGILLNEAFDKLKHNGADVVGFNCRSGPNGLLRSLEKAAASGPVLPYSVFPNAGIADYV
DGRFTFAATPEYFAETALKFADLGARIIGGCCGTTPEHISFMANALNGYKPDPSRINKLH
SKVQFTGVSTVVNGSSGESTLELVPSSTNGAAEMPPADEPNIVELVKQRHTVIVELDPPR
DLDIDKFMKGAHALKEARIDALTMADNSLAVTRMSNLALGYLVKEQTGLRPLIHIACRDR
NMIGTQSHMMGLHALGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGVAF
SGKQLKKKANFIVGAAFNPNVKYLEKAVQRLERKIEAGADYIMTQPVYDAKLIERIYETT
KHLNIPIFLGIMPLASGGNAEYLHNEVPGIQLSDDVRQRMSELKGEEGRAMGVQIAKELL
DAAMPYFNGIYLMTPFLSYEMTADLTKYVWEKSESMISTCTL
>A0A8B6X5P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Derxia gummosa DSM 723|TrEMBL
MQRSYSFEFFPPKTPEGAQKLAATRAELIALGPDFISVTFGAGGTTREGTLAAVLDVIAD
GVPAAPHLSCVGSTRAGIRDILNEYKGAGIRRIVALRGDLPSGWGEIGEFRFANELVEFI
RAETGDHFHIEVAAYPEVHPQARSASADLANFVRKVNAGADSAITQMFFNADAYFRFVDD
VRKAGVTVPIVPGIMPITNFTSLRRFAEGCGAELPRWIGERLRDYGDDLASIRAFGLDVM
TDMCERLLAAGVPGLHFYTLNAAGPVKGLWNRLGLQGRLPAKP
>A0A0E3H8S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina thermophila (strain ATCC 43570 / DSM 1825 / OCM 12 / VKM B-1830 / TM-1)|TrEMBL
MLTNFREKLNSGKFLVTAEVSPPKGTRFSGSLEDARYLKGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNVCLMTGDYPSCGDHPGSKP
VYDLDSVQLLQLVRKLDSGIDFAGNKLDGGTSFCAGAVTGIDPGKTIQLIKLEKKVRCGA
EFIQTQAVYDVGMFEEFMEVTSHLEVPIIAGLIPLKSFSMAQFMNKYISGISVPEEIMSR
IKDAPDPVEEGLSIASETIKELMKLSRGVHIMPVGSHKNTPRLLSMAGILGND
>A0A7K1T3S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adlercreutzia equolifaciens|TrEMBL
MADKEGAAGRIPFSAEMFPPKGQLTLDAARKVVEGLRAASPDFISVTCSAGGSGNGSDGQ
TAAIAELVQKEAAIPAVAHFTCVSATRASVDDAVEDLRAAGVKTVLALRGDLVPGQQPAD
FRYACELIPRLKEAGLCVGAAAYPEGHIDCLDPRENIRHLRAKQDAGADFFITQLFFNND
DFYRFREAAESAGVTAPISCGIMPFLGKSQIQRMVFLCGSSLPAPIIKLLAKYEDDPASL
RQAGIEYACNQLVDLGRHGVDGLHVYAMNQPDIACAAAEAVAAAGLR
>M6WA30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira santarosai str. CBC1416|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSRLDPDFVTVTYGAGGSTRSK
TAQILSEISKNYSFPTVSHFTCVGANQEQILKTLKEIRSSGIVNLMALRGDPPKGEGQFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPNAKNLEEDVENLKRKVDAGADFLVS
QLFFVNSIFENFLNLVRAAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A1C5Z9Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFY
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A2D0K5B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus sp. KK7.4|TrEMBL
MSFFHANHQEALNQNLAELEGQIRVSFEFFPPQTAEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDANREELCNIAHDYWSSGIRHIVALRGD
LPNGSSKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRIPSWMTRMFE
GLDDDPESRSLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A1G7BDY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax valerianellae|TrEMBL
MSASPQPLPVSFEFFPPKTPEGAEKLRTVRQALYARRPEFCSVTYGAGGSTQEGTFGTVR
EILAEGVSAASHFSCIGATRDTVRSQLATLKAMGVNRLVALRGDLPSGYGAGGEFHYASD
LVAFIRTETGDDFHVEVAAYPEVHPQARSPEADLQAFALKVRAGAHSAITQYFFNADAYF
RFVDDTQRLGLDVPVVPGIMPILGSTQLMRFSDACGAEIPRWIRMRLQGFGDDTASIKAF
GLDVVTGLCEQLRDRGVPGLHFYTMNQSAATLEICRRLGL
>A0A1X4NCZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marivita geojedonensis|TrEMBL
MPVPSVSFEFFPPQSLEASFRLWDTVQVLAPLQPRFVSVTYGAGGTTRDLTREAVATLHK
SSGLPVAAHLTCVNATRAETLAIAQDFAAAGVTDIVALRGDPPKGSDGFVAHPDGFASSV
DLIEGLSAAGDFNIRVGAYPDTHPEAADEQADVAYLKRKFDAGASEALTQFFFEAETFFR
FRDACEKAGIDKPVTPGILPIENWKGAVRFAQRCGTHIPAWVVDAFEKAERDGREDLLAT
AICTELCSDLIDGGVDTLHFYTLNRPELTRDVCHALGVTPKIGLRNVA
>A0A1C6G4K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MKLSEAMRERMLLSFELFPPKTEKGMDNLPGTIDHLMKYKPAYISCTYGAGGGNVGANRE
VCQMIRKAGTTPVTHFTVIKNTKEGIKEQLDQYLAEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDSIREAGVTMPVDVGVMPILDMSATINMALSRNGCVMDRELCRLISRNWLFPN
PFAAKDADGKPFDMFYDDKIKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLCTLI
>A0A5P8FMD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janibacter melonis|TrEMBL
MTSPSAPGGTIPQRLSSTRPSISFEFMPPKDDAGEAVLWEAIARLEPFAPDFVSVTYGAG
GSSQDRTLRVTEQIGQRTSLTAMAHLTCVSQSVDDLREVLAGYAAAGIDHVLALRGDPPG
DPGGEWTAHPQGLDHAEDLVALVREVGGFEVGVAAFPDVHPSSASLRDDVETLVRKADAG
ASFAVTQMVFDAESYLRLRDEVAARRDLPITPGLMPVTSVKQIRRMAQLMGTPLPAAVVD
RLQAVDGDPAAVRAVGVEIATELADRMLGEGAPGLHLITMNRSTASLEVLQNLSHLRA
>A0A1Q7D432|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium 13_1_40CM_68_15|TrEMBL
MPHAFDRRLAAGPLLCDGAMGTLLYARGVSLDACFDVLNVNQAKVVQSVHSEYIAAGADC
IETNTFGANRFKLAVHGLADDVRQINLRGVKLARDVRESMGRDVLVLGSIGPLGKYLAPL
GTVTADEARAAFREQAEALLEGGIDAFVVETFSDLTEIALAIETIRTLTDLPIVAQMAFT
DEGVTFAGRLPAEVARTLRELGVRALGANCSVGSSTLYEVLEAMAPEAGGVPLAIQPNAG
LPHRIGERLMYLSSPGYMADYAGRMIDAGARLVGGCCGTTPQHIAAMRRVLDARAPASTA
EPRPAGAARVIETLETPGLRTTLAPTLLGRKLEQRDFLVSVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLPTAILVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALGIRNILAMTGDPPRTGDYVNATAVFDVDGIGLLEVLRRMNEGLDATGNGIGEPTAFCV
GAALDPGAQDPGREVERFRRKLEAGARWFQTQPVYDLEVLDRFLARVGGSPVPVLVGVLP
LHSFRHAEFLHNEVPGITIPDGVRARLRAAGDGALRAGIEMAQQLVSEIRARYAGAYLMP
SFGRFEVVAEVLDVLR
>A0A0A1X610|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zeugodacus cucurbitae|TrEMBL
MHNPDYVPASNSSSVSPRIGGGYLSTPTAPTADFQPLHVRFTSEQLAPEQHKLCELFAQK
VAAKEFFYGIELSARSYGKQQTMLDYNGFGALLPLFTSLVWLGQDYANIEDMAAVDAISL
GQELQQHVVVMPHFTCYRADSKRLDDFLTLNFTNILALRGDQVVPQQQFQHAKDLVAYIR
SKRGDTVSIGVGGYPEGHPESKSMEEDMQYLKEKVNAGADFIITQICFSPESIIRFVQRC
RENGITVPIIVGVIVPDNMRILQFIMKIVKAVIPEDLLSKYKELEDDRKAFQAFAVENAV
RTVQMLLDSNLEVYGFQFFTMNRLKNVQQVIHQILSLNETQST
>A0A372EK20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga borbori|TrEMBL
MNLPISFEFFPPKTPEGAQKLRAVRQQLYARAPLFCSVTYGAGGSTQEGTFGTVREILAE
GVDAASHFSCIGATRAGVREQLAQLKAMGVKRLVALRGDLPSGYGLGGEFHYASDLVAFI
RAETGEDFHLEVAAYPEVHPQARSPEADLKAYVTKVRAGAHSAITQYFYSADAYFRFVDE
ARALGADIPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIKSFGLDVV
TSLCEQLLRGGVPGLHFYTMNQSAATLEILRRLDAR
>Q9CG56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis (strain IL1403)|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNLIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTF
>A0A556QLH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rariglobus hedericola|TrEMBL
MNPDRPISALFAENRPLRSLEFFPPKDDAGVEALRQTATALKTIPWDFVSVTYGAGGTTR
ERTAQISRLLKDELGFTVMPHLTCVGHSRAELVALADQIYDGGFRNIMTLRGDPPKGATE
FTVAPDGLRYANELVTLLKTRHPDFCLGVGGYPEKHPEAVSLEADLDALKRKVDAGAAFI
TTQLFFDNAIYHRFVDKCRAAGIIVPIVPGLMPVLSVKQVQRIATLSGSVLPAQLARRLE
VAEVNPDVVEIIGIDWALTQIRDLLAHGAPGYHLYILNRAKSALALAAGLAA
>A0A0Q4P0Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp. Leaf64|TrEMBL
MIADESRASRQTADQRPDLQISFEFFPPKTDAMEEKFWESIGKLAPLKPRFVSVTYGAGG
STRERTLRMVRRITTDAGVPAAAHLTCVGATRDEINEVIRGFQEVGVKRIVALRGDPPEG
VGQPFVPHPDGYQNAADLVAGIKKLGDFDISVAAYPEKHPQSPNWEADIDNLKRKIDNGA
DRAITQMFFRNSDYLRFVERARKAGITAPIVPGIQPIHSFKQISGFAARCGASIPDWLAE
RFEGLNDDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRPD
>A0A5C2R1Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae biotype aegyptius|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A419SGZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ammoniphilus oxalaticus|TrEMBL
MKDHLLQYIQKNILIGDGAMGTLLHGYGVPVGACGEEWNLTRPDLIREIHASYLAAGATL
IETNTYGANRETLSKYGLEDQVEAINRAAVQLAREAIGDEAYIVGAVGGILGGRKTNFDR
EKLQYAYDEQINSLLKESLDGIMLETFCNVEEAIIAIEAIKRVSSIPVLCQLSVQDLTRT
LDGYPLDEAFGRLLEAGASVVGLNCYNGPANLIRSFEKLNLPEGTLLSAYPNAGLPAYVD
GKYEYESSPEYFAESAEKLVELGIRIIGGCCGTTPEHISAVAKRLKGKEPQRVQVNERAL
RPDRVVIPYPEISSEKTIPQLARERTTVIVELDPPRELDFEPFLDGAAALKEAGVDAITM
ADNSLAMTRMSNMALGAIVKEKIGVRPLVHMTCRDRNSIGQQSHLMGLHALGIDHLLAIT
GDPTRCGDLPGASSVYDMTSFELIRMIKQLNEGIGFSGRELKKRSTFTVATAFNPNTRHL
HKAVERLEKKLEAGADYIMSQPLYDHDQFAQVAEATAHLDAPMFVGIMPLTGHRNAEFLH
NEVPGIQLSDEVRSRMAKFEGDDARKQGVEIALELLETAQRYFNGIYLITPFMRYEMTVE
LALQAKKGVKEDHLARN
>A0A7Y0E291|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pacificispira spongiicola|TrEMBL
MSEVDQIIDFMSTTTLEVTPGGAAKIDDFRAVLRDGQIVYVTFLPGSDFRDTVSTVKKLK
DQGMRPVPHFAARSIPTKDFFEENLKMLTSETGVEEALLIGGGVDNPVGEFTESMQILRL
GLFEKYGIKSLGIAGHPEGSPDISEAEVTRAMLDKNAYAKESPMHFYIATQFCFEADPLI
EWDRKIRAEGNELPIHIGIPGLATIKTLMKHAQACGIGNSMRFIAKQARNVAKLMSVSEP
DKLVRELAAYKASDPNCGIVQTHLYPLGGLKKSAAWLYAIQDGKIELNSKGGFKTEYSVD
>A0A7J7EE19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diceros bicornis minor|TrEMBL
MDHPKPRVFLARHHCPSLGIRALGAGSVRFSVPPSISLAACPLMPLAPTPCSRNPAMVNE
PRGNDGPHPRSEGSSSGSESSRDSSRCSTPGLDPERHERLREKMRRRMDSGDKWFSLEFF
PPRTAEGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASAAVNYCGLETI
LHMTCCHQSREEITGYLHKAKRLGLKNILALRGDPIGDEWEEEEGGFSYAADLVKHIRSE
FGDYFDVCVAGYPKGHPDAGSLEADLKYLKEKVSAGADFIITQLFFEADTFFRFVKACSE
IGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRSYGIEQAVSL
CRELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPI
FWASRPRSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEEL
TSEESVFEVFACYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQ
PNINGKPSSDPTVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKG
ENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPS
RMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPTPNEREMEAP
>A0A7C9P572|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Z82|TrEMBL
MNTPASILKPAAIPFSIEIFPPKGQLTLDAAREMVAGMAQAHPDFISVTCSAGGSGNGSQ
TVEVASLIQNEVGIPSVAHLTCVNSSRETVETAIAAMKAAGITTVLALRGDPIKKPAAGT
PSANASGTDSKSTAGTSASHTGATNAAAGGTTEAAAHEIGASNDAPGTGTVAGALGNASN
STVGAPEFVHATDLIPLLKDAGFCVGAAAYPEGHIDCLDLQADIEHLKRKQDAGADFFIT
QLFFDNDDFYRFRERARAAGITRPITCGVMPFLGKSQIERMVFLCGSSLPSPIIKLLARY
EDDPVALRQAGIDYACKQLVDLGRNRVDGVHVYSMNHPDIALAAAQALAEAGLRD
>A0A1Q5P1D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Domibacillus mangrovi|TrEMBL
MTLLDKLKTDVLTADGAMGTLLYSYGIDFCYEELNTENPEIIEKIHKDYIAAGADVIQTN
TYGANAIKLARYGIENRARELNTAAIKIAKKAAAPGGQFVLGTIGGIRGIRKSTATNAEI
IASVGEQAESLLSGDPDGILFETYYDFEELSESVKILREMSDVPIIAQVSMHEPGVLQNG
LSLNEALHRLQGIGANVVGVNCRLGPFHTIQAFEDVKLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGRAAVLLRNEGVRLIGGCCGTTPKHIEAAKKRLAGLPPLTEKRVKTKKPIV
IQEAKPVTDVSICEKAKTKRTVIVELDTPKTLLTEKFIEGANKLYDAGVDAVTMADNSLA
SPRISNMAMGATLKLQHDVRSLVHITCRDRNLIGLQSHLMGLDALGLHDVLAITGDPTKV
GDFPGATDVYDVSSLELLQLIKQLNEGISFSGKPLKKKASFSVAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVFTKEKIIDVYEATKHLSTPIFIGIMPLTSIRNAEFLHHEVPGI
KLSDETLERMRLCGDDQERAAKEGIQIAKELLDTAAQLFNGLYIITPFLRHDMSTELIHY
INELDALKERGIVHADSSD
>A0A327T0Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter cryoconitis|TrEMBL
MKITDHVTNAKGKTLFSFELLPPVKGKSITDIYDAIDPLMEFNPPFIDVTYHREDYIYKQ
HDNGLLEKVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADSTFIPTPGGHAYATDLLGQVNDMNNGKYLFEDHSAFQTDFCIGVAGYP
EKHFEAPNLKADFKYLKQKVDMGAEFIVTQMFFDNAKYCDFVAQCRTNGINVPIIPGLKP
ITSSKQLISLPKIFHIDLPEDLTEAVQECKNEKDVKEVGIEWMIQQCKELIKVGAPVLHF
YTMSNPEPTKRIARAVF
>A0A0C1KUX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavihumibacter sp. ZG627|TrEMBL
MKVIDHIKEAKDTLISFEILPPLKGKGINAIYNHLDPLMEFKPSFINVTYHRSETMFKKQ
ADGSFAKIEVRKRPGTVGICAAIMQHYNVDPVPHLICGGFTREETENALIDLAFLGIDNV
LVLRGDAPKNETFFEPEQGGNRYAIDLLKQVVDLNHGLYLEEEVKDPGNAQFCIGVAGYP
EKHFEAPNKSTDLAYLKAKVDAGAEYVVTQMFFDNQKYFEFVESCLAAGINVPIIPGLKP
ITNKKQMSLLPRIFHVDLPTDLSGEIMKCKSDADVELVGTEWLLTQSRELKKAGVPVLHY
YTLGKPKVIWNVVKNLV
>A0A4W3HBR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callorhinchus milii|TrEMBL
LRGGDLGQSPEEHCTRQCGGWRRSRWLRQNGGGMNQSRTEPWRLRWEESCSDSSSRESSR
SSTPSLESDRLREKMRRRIESGDKWFSLEFFPPRTASGAVNLLSRFDRMGAGGPLFIDVT
WHPAGDPGSDKETSSMMIASTAVNYCGLETLLHITCCNQSKEQITEHLQKACRLGLKNVL
ALRGDPIADKWQTEEGGFNYASDLVKHIRNKFDDYFDICVAGYPTGHPECTSYEEDLKHL
KEKVEAGSDFIITQLFFKPQTFLKFLKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKL
QVPQEIKDIIEPIKDNDAAIRNCGIDLATDLCKALLTSGAVPGLHFYTLNREVAATEILR
RLGLWIEDPRRPLPWAVSANPKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSS
PAFGELNDYYLFYLKSNCAKEELLKMWGEELVNEEHVFEVFTAYITGESNRNGTKVTCLP
WNDESLAVETNLMKAELQKVNRRGILTINSQPNINAKSSTDPVVGWGPEGGYVFQKAYLE
FFTSSENVTALLQVLKKYEPRVNYHIVNVKSENINNASDLQPNAVTWGIFPGREIIQPTV
VDPISFMYWKDEAFALWIERWAKLYPEESPSRQIIQNIHDNYYLVNLVDNDFPLKNCLWQ
VIEDMFLLKSIEKPCDDAAAVDDLAAVP
>U7PSQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183)|TrEMBL
MHIRDMIVEAEKDGLPSFSFEYFPPKTAQGVQNLYERMERMHLFGPKFIDITWGAGGHVA
ELTAEMVTQAQTYFGLETCMHLTCTDMGEAAVNDALRRAYRAGCTNILALRGDPPRDKET
WEATDGNFCYARDLVRHICKTYGNHFDIGVAGYPEGTDDNKDEDMLLDHLKEKVDAGASF
IVTQMFYDVENFLRWLARVRERGITVPVLPGIMPIATYASFMRRVNHMGCKVPARWVEKL
EPVKNNDDAVREIGKSLVAQLCRDILAGGDVKHLHFYTMNLAQATRMVLDELDWLPSADR
PRPPPALPWKQSLGLGRREEAVRPIFWRNRGKSYVSRTADWDEFPNGRWGDSRSPAFGDL
GNAYGVGLPGTNAQNRAKWGEPRSIADVASIFVRYLKGELQSLPWSESPLTGEADKIQQD
LIDLNKHGLLTINSQPAVDSAPSSDPVHGWGPPNGYVYQKAYLELLVPPALYAEVIQRVQ
AHPHLTYHAVTWKGKLETNAPGDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLG
ADWSRCFEAGSPSRTLIRGMMDEWHIVTIVNNDFHQPRTIFEVLAGLQLSDMDKEVEAEP
VEAPAAAEATPVKPDKDTVDAQAAAVPA
>A0A1L3GM44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophotalea acetylenivorans|TrEMBL
MHILDIFAANPTTFSFEFFPPKTDKAANRLYETIRQLEPLKPHFTSVTYGAGGTTRERTH
ELVMRIHEQTQLDPIPHLTCVGSPAEEIEQILTCYAKAGVSNILALAGDPPPDKPNYDRS
QDAFPQAADLVRYIRQFNERGLHPDPRGFGIGVAGFPEGHPGTPNRLLEMDYLKAKVDEG
ADYICTQLFFDNRDFYDFRERCLLAGITVPIIAGVMPIASVEGMKRMADLAGGTRFPAAL
LRSVQRCQDDPEAVRNIGIHWATEQCRDLLDNQVRGIHFYTLNNSDATKLIFLRLGLKTQ
QKTA
>A0A1P8FIA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium GR16-43|TrEMBL
MTMDPQVRAKRLLSFEYFPPKTPEGMEKLRATTRQLSQLKPDFFSVTYGAGGTTREGTLA
AVLEIRAQGHEAAPHVSCVASTRASILEVIETYRAHGIRRVVALRGDLPSGMAMSGEFRY
ASDLVAFIREKTGDAFHIEVACYPEYHPQARRPQADLAAFKAKVDAGADSAITQYFFNAD
AYFHFVEQCESVGIAIPIVPGIMPIQNFSQLARFSDACGAEIPRWMRLKFEGFGDDTASI
KAFGLDVITELCDKLLSQGVPGLHFYTMNQAGPTSTIWQRLGL
>A0A1Z4TER2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fischerella sp. NIES-4106|TrEMBL
MLDTQNPTCLTSFRTAAKAGKFLITAEVAPPKGGNPEHMLKMAATLKGRVHAVNITDGSR
AVLRMSPVIASAILIQHGIEPICQIACRDRNRIGLQADLMGAHAIGIRNILALTGDPVKA
GDHPDCKGVFDLESVRLLQVIEKLNHGFDCNDKPLTDGALDLFPGAAVDPQCPSWSGLQK
RFERKLAAGAQFFQSQLITDFEILEKFMDKIAANCGKPILAGIFLFKSAKNAQFINRCVP
GVNIPEHIIDRLAKAKDPLEEGMKIAAEQVQTAQQLCQGVHMMAVKREDLIPQILEMAGV
APVNQMVLR
>A0A346BYK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB09001|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWVAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTRFVD
KCRAGADYAITQMFFQPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A7X5UPH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora amisosensis|TrEMBL
MRRVVDRLNSAACPTFSVEFFPPRDEPDEAILWRSIRELEPLDPAYMSITYGAGGSSREG
TIRNIARVATDTTLVPMAHLTAVNHSVSELRNVIGHFAAVGVHNILALRGDPPGDVMGEW
IPHPQGLNYAEELVRLIRELGDFCVGVSAFPYGHPRSADLETDTHYLVRKLRAGADFAIA
QLFFEAEDFLRLRDRVSAAGCDALMLPGIMPLTTPRTLHKTIELSGATPPRWLLERLEPL
SDDPKAFRAEGLNVITELCERLLAEGVPELHFYTFNRSKATRELVDRLGLRSPEPQLALA
GRP
>A0A8E0RIM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp|TrEMBL
MNLKEALKNRILVADGAIGTIFYSEGLDTCPESYNLTHPKKVEQIHRSYIEAGADIIQTN
TYGANFEKLKDFNLEHRVKEIHREAVQIAKKASNKDTFILGTVGGFRNIKKSDLSIEAIQ
YHTEIQIETLVNEGVDGILFETYYDLEELLTVLKDAKAKYDIPIIAQLTASNTNYLRNGT
PIPDALEALLREGADVVGLNCHHGPYHMIKTYKHIEIPNSAYLSCYPNASLLDLEDNDLK
YNNNSEYFSDAAKELVNQGVRLIGGCCGTTPEHIKKIKNVVKDLKPIKQKNVIPIETKQY
KKQNKNEPSIKELVQQRPTVIVELDTPKHLDTNKFFDGIQALEDAGVEAVTLADNSLASV
RISNIAAASIIKQQYKIRPLVHLACRDRNLIGLQSHLMGLSLLGINDILTITGDPSKVGN
FPGATSVFDVNSSGLAEMITQFNQGINADGDTLRSNTNFSVAGAFNPNVRRLEPAVKRLE
KKIESGMEYFITQPIYEPERVKEIYEATKHIDAPIFIGIMPITNYNNALFLHNEVPGIKL
SETVLNAFEKVKDDRDATRKLSINLSKQLIDAIHQYFNGLYIVTPFLKYDLSVELANYSK
SKTETQTKEAIL
>A0A1F1URW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC08D02|TrEMBL
METRISASAPLDGIEEELAPRPQRARTALSFEVIPPRHSADSAKLDALIQGLAAYQPDYV
SVTSSHRSDWLEGTARLIERIAQTTSMRPIAHLACTAGTPDELRQWITQLIDAGVRGFLA
LRGDIPAGLDRLPDTHLQHATDLLNLIQDVADAQAYRLAAGKLALSVACYPRGHAESTSD
DQDLDVLLAKQRLGADFAITQLFFDAQDYLSFAERARLAGVRIPLIPGIMPMTSVNRVRR
MGELSGVAPPVDVIKQLEAARTPEEEHQIGMRLTVALARTILQAGAGGLHVYTHNDLAVT
RELLKGLNL
>A0A5B8DUE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albidoflavus|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A0D1ZD35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala sideris|TrEMBL
MHISKKLALAHEQDKATFSFEFFPPKTAQGVQNLYDRMDRMHDFGPTFIDITWGAGGRHS
QLTCEMVNAAQSHYGLETCMHLTCTDMERSQVDQALRLAYKAGCTNILALRGDPPREKEK
WEAKDDGFKHAKDLVKYIKAHYDDHFDIGVAGYPEGCDDNRDVDVLIDHLKEKVDAGATF
VITQMFYDVDIFLDWVGKCRDRGIKVPIIPGIMPISTYASFERRANWTKCHVPSDWYKAL
DPYKNDDAAVRDVGKDLIVQMCRKILDAGILHLHFYTMNLAQATRMILEELAMTPEKSGL
PLDKPLPWRQSLGLNRRDENVRPIFWRNRNTSYIARTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANMKLWGKPRTLQDVANLFVRFLSGDLDRLPWSEGSISAEANSIKENLL
KLNQRGLLTINSQPAVNGVSSDDSVYGWGPSGGWVYQKAYLELFIFPSIIDTVIERLNSE
KNLTYYAVNKKGKLLTNAKDEGPNAVTWGIFPNREVVQPTIVETVSFLAWKDEAFRLGED
WAKCYPAGSGSRKLIETIMDECYLVNVVNNDFHQTHEIFGIFENLQPQDLDKVFEDSPGD
ENAADGTRNVLSGDAPVSAIEKGIVNGEQRKIPFQTNGVALSN
>C1C5V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae (strain 70585)|TrEMBL
MSRQTLSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A3N9WL84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora inaquosa|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTAAGEQLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVVGRLAGVGVRNVLAVR
GDPPGNPGGEWIRHPEGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAQFVR
KCRAGAEFAVTQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAARFERVADDPDAVRRLGIEQASEMCRRLVDEGVPGIHFITLNRSTATREVWQNLK
AGARV
>A0A1D3K579|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas veronii 1YdBTEX2|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYHPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRALLTQYKGAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>H6C648|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656)|TrEMBL
MHISQKLAQAHENGKPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
QLTCEMVNAAQSHYGLETCMHLTCTDMERTQVDEALRLAYKAGCTNILALRGDPPRDQEK
WEAKDAGFRYAKDLVRYIRARYGDHFDIGVAGYPEGCDDHRDVDLLIEHLKEKVDAGATF
VVTQMFYDVDIFLNWVQKCRNRGINVPILPGIMPISTYAAFIRRANWTKCHVPPEWYEAL
EPVKNDDAAVRDIGKDLVAQMCRRILDAGIHHLHFYTMNLAQATRMILEELALTPEKSGR
RLEKPLPWRQSLGFNRRDETVRPIFWRNRNTSYVARTADWDEFPNGRWGDSRSPAFGELD
AYGVGLKGTNEANMKLWGRPKSLRDVTALFVRYLQGELERLPWSEGSISAEADTIKPDLT
DLNQRGLLTVNSQPAIDGAPSSHPVYGWGPPGGWVYQKAYLELLIFPSIFNTVLERLNAN
KNLTYYAVNKKGELHTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WSRCYPAGSGPRKLIEKMMDECYLVNIVNNDFHQTHEIFRVFDGLEVQDLDVVFEDSPAT
ESSQATTNGNGTRDVLKGDAPVSEVEKSITNGDGQKVPFQTNGVALSN
>A0A2M7SHR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_10_14_0_8_um_filter_43_12|TrEMBL
KGEVLKGFVDGVNVTDNQTSVVRMSSISSCVILKGLGLNPIMQMVTRDRNRIAIQSDILG
AAALGINNILCLTGDHQKFGDHASAKNVFDMDSIQLVQTVKLMRDEGKFLGGEELKGSPR
MFIGAAENP
>A0A544VQ55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium hodleri|TrEMBL
RTLAAIEDFNGKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLG
ELPYAQDLVRFIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFF
FNPDSYFYFI
>A0A136LFY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium OLB8|TrEMBL
MKVTDYIHEAGGKTLISFEILPPLKGGSIQTIFKAMDPLMEFKPPFIDVTYHREEFLYQM
QPTGYYQKTSIRKRPGTVGICAAIMHRYGVEAVPHLICGGFNREDTENALIDLHFLGIQN
VLALRGDARRFEDKFSPEPDGHHYAVDLIHQITGMNNGSYLDTNIEKGSRTDFCIGVAGY
PEKHFESPNLELDIKHLKAKIDAGGNYIVTQMFFDNKVYFDFVKLCRENGITVPIIPGLK
PLTKLYQLNSIPRNFYVNLPNDLVREAQKAKTDEDLKQIGIEWCIAQSRELVENNVPCLH
FYTMSDAQVVKKICSKIV
>A0A0M8QJB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces caelestis|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTFSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRSGADYAITQMFFQPESYLRLRDRVHAAGCATPVIPEVMPVTSVKMLERLPKLSNAVF
PEALKERILAAKGDPSAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A494RJT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas naejangsanensis|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRNAVNVSFEFFPPKSDEAEANLWKAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRDEVDEVIEGYKAIGVDH
IVALRGDPPGSAGIGGAYTPRADGYANATELTAALSRIGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVTNFAGLKRMT
AACGAALPDWLAAHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAVA
>A0A660RP70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga sp|TrEMBL
MREALEKSKGVILEVLTPRGSNLRKFLEFTEKMWETGIDAFSVTDMPLGKVRMAPWAGAH
FLLERNMDVLMHFTRTTRNMIRIQSDLLGSYALGVKNLLILSGDDPKHGDYPNTTRVNDI
SITDLIKLAKSLNDGKDLGGRTIKPSTDFYVGAVFNHRDNTDLVKAKEKIRAGADFLISQ
PVFDVKEVENVIYELNEVKLVLSVVFFKSEKQFKIFSQVPGVNIPRKYLEDLENKSDEYI
RDYTLSKVLEIVDTLKSKVDGFYVVGIVRDIESVRRLVEIAKGG
>A0A7C6MRQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MTTAAQSIRELKAPAFSFELLPPLKGNSISRVYRTIDALKDFKPLFVNITSHRDEVVFRS
ADGGLYERKVTRKRPGTVAVAASIKHRYGIPVVPHIICSGFTRSETEYALIDLNFLGIHD
VLLLRGDKAQRDRFYEPAEAGNAYAIELIEQVNNLNKGVFLDDTLAEAFETPFSFGVAGY
PEKHEEAPNLDSDLFWLKKKVDAGAEYVVTQMFFDNSKYFAFVEKCRAAGITVPIVPGLK
PITLQNQLTVLPKIFHTDIPEDFARALRTCKNDEEAARVGVEWTTMQARDLLDNGVKLLH
FYTMMATQSVRKVAEQIY
>A0A7X9ICB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MTVLELIKNAKGPLFTFELLPPLKGHSIERIYSTIERLLEYNPAYINFTTHRNEIIYRER
PDGLLEKKIVRLRPGTIALAASVKYKYNITVVPHILCGGFTKEETENALIEMKFLGINDV
LALRGDPQKGSRVFIPEKNGHKHTSDLVKQISDMNRGVYLEESIENAEPASFCIGVAGYP
EKHFEAPNRQVDIEYLKLKVDAGAHYIVTQMFFNNDRFCRFRDECRKAGIEVPIIPGIKP
ISALNDINLLPQTFHIEIPNDLFRAVKKCKNDEEARETGIEWAVQQSKELIKMGVPGIHY
YTLGRSDNIARIVKSSF
>A0A7X7EV92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSFFTPLRRWQPAFRPFSRPPAGRRFLALTERVVKGPLFGCRMCGNCLLQETAFICHMAC
PKGLRNGPCGGVNNGYCYVDPTRRCAWYLIYERSRRMHREHKLLEVLPPVDWDRAGTETW
GEVVRAARKAGFKKLFIPSAREGKKLREVLEEKVFRPIRQPDWWKGDSEYHPPAVTEPQS
ALERELRSGRFVITAEVTPPLSAATGRLKEKIMLVKPWVAAVNFTDGSSAVPRMSSAACS
AVAASLGVDPVLQISARDNNRNSLQSMAIGANAIGVHNILCLSGDSPRVGPTPRSNMNIN
DIDSVQMLWILRRMRDEGIYLDGREIKNRPGLFLGAAAAPNSMDPAMQAIRIRKKINAGA
QFLQTNLVFDPDSLDPWLEQLDREGLLDKVFILAGICPLKSLRLARYLNDNIPGVNVPEQ
VMKRLADAGDRFAEESIAITVENVKKLREKKGVNGVHIMPLGWEESVSLIIDRVASRPCL
TDN
>A0A401ZYX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tengunoibacter tsumagoiensis|TrEMBL
MKHLVLERLQQGPLLCDGAMGTLLYARGIPYEHCFDEFNLSQPDVIQGIHNEYISAGAQI
IETNTFGANRTKLEAYHLASKVYEINYKAARLALEAREVSGQPVFVAGAVGPSGLLLRAP
DQPRLSDLRAIFREQIEALQTGGVELLILETFSSLPELRQAILAAKDVGGLPIIAQMSFD
EDGYTLSGQSAARVATILADLGVDVMGANCNVGPAATLDALTEMITSVQQNPEITRPILF
SAQPNAGLPRRIDNRFFYVSTPDYFADYATRFAQAGVRLIGGCCGTTPRHIAAMRQALDK
SYGHDPQFALELSTTPPSVQTNGHQPIEEEIIFPHEGTRTRLQTQLDAGEFIVSIELDPP
KGLNPTKLIAGAALLKEAGADCINIADSPMASVRMSCLALARLLHDHLDLETIIHFTTRD
RNLMALQAELLGAHALGIRNILALTGDPLRVGAYPNTTGVWDVDSIGLIQILRGMNEGHA
SSGSSLGAGASFHIGCALNLNMTDEETDLEIEKYQRKIAAGANFIMTQPIYELAPLERFL
SRAGNPPIPLLLGNVLLYSSRHAEYLHNEVPGISIPEDIRTRMKEAGEDGYEEGIKIAHE
LLTEARDKIQGVYLMPSYRRYDIVCELIRALKAPGTVK
>A0A0J6NZ10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. LK2|TrEMBL
MNLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADIIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPKHIAGMKRAIANIAPVIAKETIPRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQQLIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEVKEGIN
>A0A832LCL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKLTNIFQVAEKTFSFEFYPPRDEIAAVDLGINIGQLIKLSPSFVSVTYGAGGSTRSRTF
DLVDFLKNSIGLNTVAHYTCVGNTRSKTLEDLKTLRMLGLQNFMLLRGDPEVGSKYGFIP
CYDGFANATELISYAREHIDDCCIGGGAYPEVHPESLNAEIDMKNLKKKVEAGCDFLITQ
FFFDNKRYFDFVARARKAGIKCRIIPGIIPLTRYSQLERFVNLSRASIPPAFLEQLESNR
YNPEAIYKAGMDFAIRQCRDLLMLGAPGLHFYTLNKSRATVEIYQTLLVR
>A0A6N9J0W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium|TrEMBL
MKISEKLRLSAPIFSFEFFPPKDSEGFASLFETIARLKVSDPGFVSVTYGAGGSTRSKTV
DLVGNIKNFIGLESMAHLTCVGHDQQEIRSVLESLQSRNIDNILALRGDPPQGEEKFLKT
EGGFEYGNELVAFIKKNFSFCVGAACYPEGHVECKDLDKDIENLKRKVDSGADFLVTQLF
FDNKHYFDFMDRAAKANINIPVIPGIMPVLNLKQIKRFTKMCGATLSPGLINKFSGIEDD
SEKVRQIGIAHAIEQCRELLENKAPGIHFYTLNRSKATLTILEALREFT
>A0A7Y5LJ12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacteraceae bacterium|TrEMBL
MPVFTPGRRWQPPFYPFKREPLNRRVLARIERLVKGPLWGCRMCGNCLLQETAFICPMEC
PKGVRNGPCGGSTKEHCYVDETRPCIWYRIYERAFAMGREEKLLEVLPPLDWDKTGTETW
GDVWRQARQVGMKKVARGMLSRDPARRAEHWDSVFHPVRQPDWWQGDAEYHAPKYTEPVS
ELERRLKAGEFVVTAEVAPPLSVNTDKLVRHINVLKKYATALNFTDNASATPRMSSVACS
KIALEHGAEPVMQINARDKTRVGLQSEVMGASALGIRNLLCLTGDSMAMSPGPKGRMDIV
DIDSIQMLWILRRMRDEGKYLDGREIKTPPQYFLGSAASPFASNMKFQALREQKKVNAGA
QFFQTNLVYDADGLEIWLNELAKRNILDKIYILIGITPLKSLKMAQYMHHDVPGVFIPEK
ILKRLEAAGDGAQEEGVTIALELIEAIRNKQGVNGIHLMAVGWEEIVPRIVTEAGLLPRD
FSPPVVDIPKAAA
>A0A7X5YW50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium kitahiroshimense|TrEMBL
MKIVDHISNAKGKTLFSFELLPPAKGQGIQSIFKTMDALMEFKPPFIDVTYHREDYMYKK
HESGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDPDFIPTEGGHAFATDLLQQVADMNQGQYLHEDIAISEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVNKCRENDIHIPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSEAVSGCKNNADVRQVGEEWLVQQCKELIDFGAPVLH
FYTMSNPGPTKSIVEKLF
>A0A353BK46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium|TrEMBL
MHITEHLQNAKGTLISLEITPPEKGHSIQGIFDTVDRLAPFSPSFINVTYHQTSIVYEEE
DDVIRKVPKRKKPGTVGICAALANRYLIETVPHLICGGFDRYETEDALIDLHYLGFENLF
VIRGDPPPGFKEYRPEPDGYRHASELVEQIANLNRGKYLEELDDAVPTSFCMGVAGYPEK
HYESPNLAEDIQRLKEKVDRGAGYIITQMVFSARVFGEFVKRAREAGIGVPIVPGVKVIT
GEKQLVSIPRDFHLDLPEPLVEGIKGAASPEEAKRFGTGYAVGLCRDLLDLKVPCIHFYT
MGRSGAVADVLGRLKGRGL
>A0A444H7H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. (strain K172)|TrEMBL
MSPPTLTDTHSNLSAATAPVALSYELFPPRSPKAAETLWTTIRELEATDPDYVSVTYGAS
GSNRDTAVDLINRLLLETTLRPLAHLTCVGNTPAELADIIAELLDHGVRGILALRGDLPQ
DGTLPPSGSLRYAQDLIELVRHVEQRRTALLCAGKIAVGVAAYPAKHPESPSVEHDVEVL
LAKQRSGADFAITQVFFQAHEYSNLVSRARRAGVTIPIIPGVMPFTSLRRLKRLGELAGV
DPSAHLMERLAAADTEAEQRRIGVAATVDLANAALDAGAPGIHLYTFNEHAHALDVLDKL
ALPRPARPTFRAQPVSPTPEPVRHEEFAI
>A0A545T394|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliikangiella marina|TrEMBL
MGFHHAQQVELLNQNLFDLAGKVNVSFEFFPPNSEQMENTLWQSIKRLEGLSPKFVSVTY
GANNSTRERTHRIISKIQKETSLVPVPHLTCIGSTRAEIVELAEQYWQEGVRHIVALRGD
LPEGENSPQNQMYALDLVKLLKSVADFEVSVAAYPEVHPDAPNPQFDLINLKRKVDAGAS
RAISQFFFDTETYLRFRDRCVTSGVDVEIVPGILPVTNFKQLLKFSAITNVSVPGWMHRL
YDGLDNDPMTRNLIAANVAIEQVKVLAKEGVRDFHFYTLNRSDLTYAICHSLGVRESLVE
ETSLVVNG
>A0A351RSR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium|TrEMBL
MKFIEKIKNSDRVLFTLEIVPPEKGYSLRELFDTIESVKEFSPAVIDVTYHRADCIQVRD
KNGLTIKTMKRKRPGTVGICSAIINKFGIDPIPHIICGGFTKEEVEDILIDLHFLGINNL
LLLQGDKLADEPHFMSTKGGYSYAYELVESVSNMNKGLFLGDETIMEEKFDFCIGVAGYP
EKHYAAKSFEEDLKNLKNKVDKGADYIVTQMFFDNQKYFNFVREARRLGISVPIIPGIKP
ITSKKQLKIVPQKFFTDIPVELSREINSSDDSERIKEIGIQWCVEQCKELMKNKVPALHF
YTLGKAYPTVDVLRRIF
>A0A0U5EX27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter senegalensis|TrEMBL
MSLSRLSVELIPRSTEALLDDVASVKALFPAADTLNVPDLMRFPLRSWDAAALIHPHFAR
VVPHIRAIDIAPDAPLPGADQPGLEEVLVVHGDPPADLSHRTYPNSTESIIRRYKKEAPH
LRIYAAFDPYRRAPWQELEDVARKKEAGAEGFFTQPVFDLKLFDLCREWLRDETVFWGLS
PVIGPRSRSYWETTNHVVFPKDFEPTLEANIQFAQTVLRHLSQEKGRAYLMPLRVKLDQY
LPPLLEALA
>A0A1H1WZ43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microterricola viridarii|TrEMBL
MAAYHHVSPRAGGHSGVVTPVSFELFPPRTDAAALALGRTIDKLAEADPAFISVTYGAGG
SSRERSLTVLRYILEHTAVEPMAHLTCVGSSHAEANSLVRQFLDAGITSFLALRGDPPSG
VTGPAELGDLGSAAELVQLIHRVQEEREPFSQKRVPGASQGSRIARRRRPERVAVAAFPN
GHPRARGSSADVDSLLAKQVAGATLAITQLFFHADDYLGFVDRARTAGVTIDIVPGLMPA
TTPTRLARIAELTGEEIPAELEIALEVEPSEEGQHEIGVDYIARVAAEVLAGGAPGLHLY
TFNQHRAVLGVLERLGRMPAVAGR
>A0A0D2BKY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala spinifera|TrEMBL
MHISEKLASNLKENKPSFSFEFFPPKTAQGVQNLYDRMDRMHDLGPLFIDITWGAGGRNS
QLTCEMVNAAQSHYGLETCMHLTCTDMERSQVDRALERARDAGCKNILALRGDPPRDKEK
WEATDGGFRHARDLVKHIRAKYGNVFDIGVAGYAEGCDDNRDVDVLIDHLKEKVDAGATF
IVTQMFYDVDIFLKWVQKCRDRGINVPIIPGIMPISTYASFKRRAEWTKCNVPKDWYEAL
EPVKNDDAAVRDIGKDLIAQMCRKLLDAGILHLHFYTMNLAQSTRLILEELALTPETSGK
PLEKPLPWRQSLGLNRRDENVRPIFWRNRNTSYIARTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANIKLWSKPRTLREITELFVRFLSGRLERLPWSEGTISAEANIIKEDLI
KLNKRGLLTINSQPAVDGAPSSDAVHGWGPPGGWVYQKAYLELLAWPSMIDTIIERLNAD
KNLTYYAVNKEGKLITNAKDEGPNAVTWGIFPNREVVQPTIVETVSFLAWKDEAFRLGED
WAKCYPAGSASRKLIQAMMSECYLVNIVNNDFHDTREIFTVFEGLEAQDLDHVFTDDGTE
AAHNNDTRDVLNGEASASEIERNITNGDQHRIPFQTNGVSPVK
>A0A0Q5B7I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. Leaf296|TrEMBL
MTRARFEIIPTADIAERARRAFPDPSTVVLTVTSLPKHGLDRTLDAAVELAALGFGVVPH
LAARTVEGRPALERALGRLGDSGIGEAFVVSGDAKKASGTYSTSLELLRDAVEIMPGLAV
GIAGYPEGHPHLSDESILKHLRERAPYIRSIVTQMCFDVDAVARYADSLRAEGIDAELWA
GIPGPVERAKLLSLGAKIGVGSSLGFLTRSSSVAGGLLRGRRFDPTAFVGRLEAAAGDRF
HGLHVYTFNELDGLASFGA
>A0A450U8Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. LFY|TrEMBL
MTTMNLSGSNTRVFSFEFFPPKTPKGHDKLRTTWQRLSRLNPDFFSVTFGAGGSTQSGTM
ETVLEIQKHAGIDAAPHLSCIGSTRVKIRKILDHYLSHGIKRIVALRGDFPPDMVKLGEF
RYANELVEFIRAETGTDIHIEVAAYPEFHPTAPSASVDLENFKRKVDAGANSAITQYFYN
KDAYLRFVDNCERIGVHIPIVPGIMPITNYVSLAGFSQRCGAEIPRWLDWRLQEFGDDMS
ALQSFGIDVVTELCRQLLEAGAPGLHFYVLNRVQPVMTIWENLDLPKIRDST
>A0A2A4NA26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVIELLNQAIENKTTHFSFELLPPLRGNSISKVFNTIDKLKEFDPKYINITAHRDEMVF
TESANGIIEKKITRKRPGTVAVAAAIKNKYKLTVVPHVICSGFLPEETENALLDLNFLGI
YDLLLLRGDSSSRHDFISSNGEHKYAVDLIKQVDEINKGNFLDGTHVEPFETPFSFGTAG
YPEKHEEAPNLDSDIYWLKKKVDAGAEYIVTQMFFDNKKYFDFVKKVRDAGITVPVVPGI
KPISALSQLTVLPQIFKTDIPEALAAEVRKCKTNDEVKQVGTEWGIEQCKELIQYGVPSL
HFYTLMASNCVRNIAKAIY
>A0A5D2XLC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium mustelinum|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGVKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQYPYGQWDDSRNPS
YGALTDHQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSYCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGDVNAVTWGVFPAKEIVQPTV
VDPASFMVWKDEAFEIWSRAWAALYPEGDPSKKLLEEVQSSYYLVSLVDNDYIGSDVFAV
FGDL
>A0A0D0Q5C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenxinia marina DSM 24838|TrEMBL
MSVLSFLRRKDAPATTTGSGELEEFLQGYSIEVMPRTAEKVEDFRAILPAGTRVYIAHIE
GTPIEDMVATAARIRAEGFEPMPHFPARIVKDAATLQEWIARYQDAADVKQGLILAGGVK
EPVGEFHSSIQMLETGLFDQHGFTRLHVAGHPEGNRDIDPDGSDRMVSEALRWKQAFSER
TDAQMALATQFSFDAGPIIEWADRIAAEGIQLPIHIGIAGPAKLQTLIKFAIACGVGPSL
KVLQKRAMDVTKLVMPYEPDEVLTALAAHKAAHPGFGIEQVHFFPLGGIKTCAKWVTENG
GAAGVPAAASA
>A0A8B7I9E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apteryx mantelli mantelli|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDK
WFSLEFFPPRTASGAVNLTSRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKHLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A6M1UKZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium SGD-2|TrEMBL
MSLTQTISLEFFPPREESARLKLEEAARRLVAHRPAYVSVTYGAGGSTRAGTADTVKFMQ
SLGCDTAPHLSCIGSSRAELVEILEGYRAQGIRRIVALRGDLPSGMGRHPGEVHYADELV
SLIREHFGDVFHIEVAAYPEVHPQAGSASKDLDHFIGKVKAGANGAITQYFFNVDAYFDF
VERVQGRGIDIPIVPGIMPITNYKQLARFSNMCGAEIPRWLEARLVDFGDDMASLREFGA
DFVAGMAQRLLDQGAPGLHFYTLNNAKATLAVWQRLNVA
>A0A8C6UX74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neogobius melanostomus|TrEMBL
MVNQVQRGDGTLSSRSDSSAASASGGDSSKESSRCSTPVLDADRTDRLRYKMRRRMESGD
HWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPSGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQSKDNISRHLSKAKHLGLKNIMALRGDPVGSDWEEEEEGFNYAVD
LVKHIRSEFDDYFDICVAGYPTGHPEAHSYKEDLIYLKEKVAAGADFVITQLFFRAETFL
KFEEDCRPSGSPCVCVQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIHQAL
EMCRVLLDSGRVPGLHFYTLNREVATMEVLRQLGMWQEDPRRPMPWAVSAHPKRKVEDVR
PIFWGSRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSVFEVFTCYIAA
QPNRKGHKVMCLPWNDEPLAPETNMLKDELEKVNTRGVLTINSQPNINGKPSTDPIVGWG
PPGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTW
GIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNL
VDNDFPLDSCLWQVIEDMFELLQTGLDTGDAPKGNNRIKCVFIVDEK
>A0A0G1TCP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parcubacteria group bacterium GW2011_GWA2_47_10|TrEMBL
MFPKFNDSLKKLRRAGVKVFDVNSSRRICHDSIQLASELCGTSADVIAHITTRDSSVNGL
LNQILAAYEWSDLKNFLVITGDPYESKQAVFPSRGVFQTDSIGALKAIDWQFRKNLARPL
NIVLAAAVNQNEHDRAKEGKRIEEKIAAGTDIFMSQPVFDSVQADELFKFYGEHSARPLF
VGVWPTLNLKTIENIRAGSVEGVRLPRKEYSELISSFTDENELRRKSAERTIGLVRHIRS
SGKATGIYIVAPSRNPLLLLPILKELL
>A0A1S9D2S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium USCg_Taylor|TrEMBL
MGTPNSHSFSFEFFPPRTPEAIGKLQVTRDRLARLKPDYFSVTFGAGGSTRELTFETVQE
IRAATGIAAAPHISCIGSTISSLREILSTYRSAGIKHIVALRGDLPSGAAGHGELRYANE
LVEFIREESGDYFFVEVAAYPEFHPQAPSADMDLRNFKRKAEAGADRAITQYFYNLDAYW
RFVESCGALGVQIPIVPGVMPIINCTQLVRFSDACGAEIPRWILRRLKDFGDDRVSIRNF
GIDVTTDLCRQLLDKGAPGLHFYTMNQAEASEAIWANLGLRRERPAVKLSGG
>U7R124|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus temperata J3|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSIGRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWNNGIRHIVALRGD
LPDNSEKPKMYGADLVELLKKEADFDISVAAYPEVHPEAKNSQADLICLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQLKRFATMTNVRIPSWMTRMFE
GLDDDPESSNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A1S9NHX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces antibioticus|TrEMBL
MTGKDVAHLEAAREAVPPGTRVNVAFLGTETQELRLAAVRAAARLGFVPVPHLSARRLRS
RAELAEFLAALREADATERVFVVGGDPAVPRGPFPDTLSVLRSGLLQEYGVRHVGVSGYP
EGHPAIDGPVLWSAIEEKAAVLREQGLDGSVITQFGFDVEPVLTWVEELRSRGVDLPVRV
GVPGPAGVRRLLSYATRFGVGTGAGIARKYGFSLTNLMGTAGPDRFVQDLAEGYDPVRHG
DLGLHFYTFGGLAATADWVAARA
>A0A2I2FP07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus candidus|TrEMBL
MEKITDKIAALPPDENYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
ATRSLELAEVCQRQLQLTTCLHLTCTNTSRELVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAIDLVRYIRQQYGDYFCVGVAAYPEGHPVDSFQDTQDPERDLPYL
VEKTRAGADFIMTQLTYDVDAYVNFENRLRTHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVHIPPPIIKKMEEVRFDDDAVKRIGVDVLTELVGGIRKIPRPAQRGFHFYTLNLEKT
VSFIIERCGLIPEYADDSDALVDGGSLSALDLSATGPNGASRSASRRRRSSLNSLPHNRV
IVDRPQFAESSRSSMTHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLKVAPAVARRVWGYPVSRDDISALFRRHVSDELYIVPWSEGGA
EENSSGLSPETATIRPELLQLIDKKGWWTLASQPAVNGRRSDDPVFGWGPPGEGFVFQKP
FVEFFCPNKDYTTVVKPLLQKHGHEKLAWFAVNSKGDFQSSMPSQSSEADPIEINPENVN
AVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIHPRGSATERFLNDTKNDVWL
VCVVGQDFGAGTKVGSKEEQEERSWMWRELIES
>A0A1Z9JB40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium TMED177|TrEMBL
MGLATALQRAIESGQQAITAEVMPPRGGDPAHTLAMADQLRGRVHAINVTDGSRAVMRMS
SMAVCRLLLDRGLEPVLQLACRDRNRLALQGELLGAHALGIHNLLCLTGDPVRAGDQADA
RPVNEFESVKLLRQVAAFNRGEDPVKSDLVDGATSLFAGCAADPQSRSWSGLQRRLQRKQ
EAGARFVQTQMVMDAKALERFQTELAGPLGLPVLAGVFLLKSAKNALFINRVVPGACIPN
ALIERLESASDPAMEGVAIAAEQVQRYLGMVQGVHLMAIKAEDRIPLILEQATVSLPQV
>A0A369L8B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraeggerthella hongkongensis|TrEMBL
MRRIDDIFATRKQPVSFEIFPPKGDLTLDAAHGVAASLADLVPDFISVTYSAGGSGNQQA
TAEVASLIHHDFDVPSVAHLTCINSTEEALTAAIDDLRRRGVSNVLALRGDVVSACDPSP
FKYAKDLIMRLADEGFCIGAAAYPEGHIECTDFKASVAHLKQKQDAGASFFVTQLFFDNQ
YYYRFREAAERAHVTVPITCGIMPFLSKAQIQRMVFMCGASLPSPIIKLLAKYENAPDSL
RSAGIEFACEQLVDLQKHGVDGLHIYTMNQPDIARACVSALRGSWGAEGGRHGGL
>A0A2W1LJB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sambharensis|TrEMBL
MRISIELIPRDLTRLQQELDMITASYRQINMVNIPDLMRLQVRSWEGAKQAVDCLPEAVP
HIRAIDFDLRQPFVLGEELMRGGIREVLIVAGDPPADMKRKVFPTTSTELIRKLRQEYPE
LKVYAAIDPYRAGLREELEYAQRKLEAGAAGFFTQPFFDLRHMELFAEQLEGIELYWGVS
PVMTDGSQGYWETKNRAVFPRDFRPTMEWNVAFARRALQFAKDSGNYFYFMPIKVDLKTY
LDGVFAE
>A0A2N0L953|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G4|TrEMBL
MAKVTEKCFESTGNSCFICDFSPPRSGDLSILQTTDIGSDFISVAYNPGRAVRANSAMLA
AAIKQHSGTDVIFTLATRDMNKLALQSLMLGAQLLDLENVVVVQGDPFSQRDLEIVQGAD
DTHPTQLISGIQAMNQGVDFRESQLRAATEFCVGATADLGRGIEREAELAVRKVGAGADF
LVSQPIFDVTEADRFRQAYEKQSRTELSIPMFFGLQILEKDGVLFSSVPNGVREELEQGR
SGVDIAFELYTQFLENGLQNVYLMPPIRRGGARNYEAAQEFLDQAKGL
>A0A2K4Y6E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium ahvazicum|TrEMBL
MEFGPCGGVRPDGQCEMRSGACIFAEVVPWSGIVPATRPVRAPLVLTDFSATPFDRNDIA
ATAAVLAPGCDAVLVGEHQNKPDFPPTLMGSLLVDAGVTPWITLSCRDRNRVVLEQELRG
LHSIGVETVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGTIAAVPETPTAPPVSA
RPDRLVEKQRAGASLAVLNHVPFPKMIADFMAAAVSAGVSIPVIAAVAVFTDSVSAAVLQ
GLPGLELDESVTERVLGAADPVAAGIAAAVDEARALLSIDGVAGVNVSGLASASGGRLGA
EIKAEVGRLIRAEAS
>A0A328C5G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lujinxingia litoralis|TrEMBL
MSQIQMQSPFLSAIEEGPVVFDGAIGTQLYERGIYINKSFDDANLSSPDLVAAVHAEYLS
AGAGVLTTNTFSSNRIKLRRHGLEQRAPEIARAGARIAREVAGDLAFVAGSVGPTGRTPT
MLTEGELEEMRQAFREQIAALVEGGVDLILLETFRQLAEVRMALEAAREVCDLPVVAQMS
FDGERRTGDGADPERVAMLLREWGADVVGANCMEGPHVLYDVVVDMLSCGLPVIAQPNAG
YPRKIDERLVYMATPEYFGVYARRFFKAGVRLVGGCCGTGPEHIRQVAAAARMLGGGRAS
LEVSAQRSARPEAAHEEVASLKSPTRLAEKIEAAHRARARNEAVSRENFVVSVEVNPPSG
LRADRALDAARMLLEGGVDAINIADGPRASVRMANWALGRLLQETLDIEVILHLCGRDRN
LLGLQSDVLGFEALDLRNLVVITGDPPKVGDYPHATAVFDLDSVGILRMIENFNHGVDPA
GKPVGDATAFYCACGAEPAAADYERELRRLELKKAAGARFVMTQPVYDPEVLDRFLADIA
HLDMPVLVGLLPLASARNAEFLHNEVPGMAVPAEVRRRMHAAGTGQAARAEGVRIAQETL
LAVGSRVAGAYIMPPFGRYQAALEILSCLPGYALTPALEEAR
>A0A3N6DJJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia endophytica|TrEMBL
MGLLEDLQSKILIGDGAMGTLLHAHGIDNCFEELNITKPEDIFNIHKAYQKAGASVIQTN
TYGANFPKLKRYGAEEKVKDINIEGVRLAKKAVGDAGYVLGTIGGIRSFQKSIISLEEIK
RSFREQLFWLLSEDVDGLLFETFYDLEELKTVLEIARHETDKPIVTNVSLHEKGVLQDGT
PIVKALKILEELGADVVGTNCRQGPYHMLEILEEVPLLDKSFLSAYPNASLPQYVDGRLI
YETDPDYFYKTALAFRDQGVRLLGGCCGTTPSHIEAMAKALTNAVPITEKTVKEAPPIEV
LSQEIQAQPHLHEIVQENHSIIVELDPPKKLGVDKFLKGAHALQAAGIDALTLADNSLAS
PRISNLAMASLLKDQLKTRPLIHLTCRDRNLIGLQSHLMGMHTLGFNQILALTGDPSKIG
DFPGATSVYDLSSFDLIRLIKQFNEGVSFSGKPLGQKTNFSIAGAFNPNVRHLDRAVQRL
EKKVDCGADYFISQPIYSIEQLEDVYEATKSFKAPIYIGIMPLTGAKNARFLHHEVPGIK
LSENILTRMEKIEHDKEQSAKEGIRLAKELIDRAYELFNGLYLITPFMRYEMTVELANYI
KAKELVSIERKI
>A0A7H8UC88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMFATDLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A2N2P2K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-10|TrEMBL
MPIFTPGRRWQPIYYPFRRETFGNRLLNSIEMLYKGPLWGCRQCGNCLLQETAFICPMEC
PKGLRNGPCGGSTAEHCYVDETRPCIWYKIYERAFKLGREELLMEVLPPLDWDLVGSEQL
GRLVEQIKINGTRNVISGLTSKDAETREETWDGIFRPVRQPDWWQGDSEYHVPKYEEPAS
ELERRLKAGEFVVTTEIQPPMTASTKKLKDNIDLMKPFVTAVNFTDGASATPRMSSLACS
AIAVQRGAEAVLQIAARDITRVGLQSEALGAAALGIRNILCITGDSNRLSPKPKGRMDIL
DLDSIQMLWVLRQMRDEGKYLDERNIKFPPKYFLGSAASPYASEIKYQALREHKKVNAGA
QFFQTNLVFDIERLETWLNALAARNILDKVYILVGISPLKSVKVARYMHDEVPGIHIPEA
IMKRLSDAETAGNAAEEGIRITLELIEKIRKLEGINGLHIMTVGWEEVVPRIITEAGLLP
NHSSAAG
>A0A0M1I797|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. C15|TrEMBL
MSSLASYFQQRQFCVLVEYLTSLTPYHPLQTEIAGYPTVMALADRVHSDHDLAPLDASRT
YDSAVEKLLHFSGKDRDIQDFEAFLAQAKAANIQNLLLLSGDKLKSHSDGTDGRPRTRYL
ESVNAVAAAQHVGGFHIGVALNPFKYVEAERDAQYLKLHKKLKAGADFIITQLGYDIKAL
QQAKAFLTSHDYAQKIVACVMPLTLARANYMIKHKVAGIVITPHMLNVLKYEKQTGQTAH
VYARCALQILICEQLGFAGVHLSACHKPDEQARLAEYIEEYRHLDLAALEQHYKRLWHIQ
TGLELQPERLPSARKPSRLEVVKYRHLQFMHDALFMSKPAKNAGRFIFKAAFWNTHLMTK
MLLKTESFSKHRLVGCESCGQCRLADTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVEQTQILKDKLIPTVPIATRGSSSWKNWYLAVEA
>A0A7J9ZKU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangiales bacterium|TrEMBL
MTFLDELGHRLLIGDGAMGTMLHAAGNSLDLALPELNVSNADLVSTVHESYLSVGADVLT
TNTFGANRLRLAGQGHALAVREINLAGVRLARRAARSAGRPVYVAGSLSPAVTAGQRRKV
APADRAAAVREQVEALLEGGVDVLLLETFGHLEELTEAVEVAAGLDAGVPVIAQATFTSD
GRTLGGESPHEVATALAALPVAAIGTNCTLGPQAMLEVVRELRRATTLPLTALPNAGLPR
RVRGRRFEYNIDGAYVARYALRYAEAGAALVGGCCGTTPSHIQAVSAALGDRRERRVTAV
PRAPAPRTAPPEPADHDTLAVRLAEGRQVLGVEVRPAPGGLAEETAELVVRLRDRGAGLV
LVSPTESPRAQPGSVNLALHLGQSIGVTAVPAVPTWDKTIMTLQADLLGAHALGVRSVVC
ETGNPPLRGDYPNVDGIWEVDSVGLIGLLEGLNRGHDSGGLPLATKTGFHIGARFNPGSG
DPVAELARTREKLLAGAQFLISRPVYEASGFLRMAEALGGEVPLLVTVAPLRDYAEAEFL
AHEVPDVTIPEETLRALDVAGPAAPRVGRELAAQLVRELRPAAAGLMIAVGPGPADQAIE
LLGEI
>A0A6I6UVH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rossellomorea vietnamensis|TrEMBL
MPLLEALKERILIADGAIGTLLYSYGVDRCFEELNLSHPNEVLKVHKEYIDAGADIIQTN
TYGANYQKLSRYGLEDSVKEINTAAVRLARKAAGENTYILGTIGGIRGIKQNVSLEEIKR
SFREQLYCLLLEGVDGILLETYYDFEELTTVLNIAKREADIPVIAQVSLHETGVLQNGME
IKDALQQLELLGADVVGINCRMGPFHMVNSLEEVPLPKRAFLSVYPNASLPNYEEGRFYY
SAEPDYFGDISNELRLQGARIIGGCCGTTPDHIRSVAARLKSREPVKEKKVKKKKVVQLS
SPSIKGSLLHEQVREKKTVIVELDPPKHLDTKLFFQGAAALKEAGIDALTLADNPLASPR
ISNDAIGSMVKSKYDLTPLVHITCRDRNLIGLQSHLMGLHTLGIHNLLAITGDPAKIGDF
PGAASVYDLSSLELIELIKQNNEGISFSGKSLRERTQFSVGAAFNPNFRHLDASVKRLEK
KKKAGADYFISQPIFGKEQLIQVYEATKHLDVPIFIGIMPLISSRNAEFLHHEVPGINVP
EETRRRMKEAGNDPVIAGAVGMEIAKDLLDTAIQLFNGIYLITPFVRYDMSIELIHHIQE
KTNTEREVPYGHHIV
>A0A379G8B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia rustigianii|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSAEMEQTLWKSIDRLKNLKPKFVSVTY
GANSGERDRTHSIIKDIKDKTGLVAAPHLTCIDANPEELKSIARDYWNNGIRHIVALRGD
LPDNSNKPEMYATNLVELLKNEADFDISVAAYPEVHPEAKSAQADLINLKKKIEAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLERFAKLTNVRIPTWMSKMYE
GLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A1X0WDP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rouxiella badensis|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTREMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAELRQIAQDYWNSGIRHIVALRGD
LPPNSGKPEMYATDLVHLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANSA
ITQFFFDVESYLRFRDRCVSAGIDVEIVPGILPVSNFRQLQRFATMTNVRVPNWMTNMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGVPASL
AQ
>A0A523WE84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MNTKKTPSKLEKILAAGHLAVTSECGPPRGSNGDTITKKAEMIKDYVDAINITDNQTSMT
RLCSLASVIHLKLMGLDPVLQMVTRDRNRIALQSDILGAASFDIYNILCLSGDHQSFGDN
PQGQNVFDLDSIQLIQTVRLMRDEGKFLGGDDIDQPPKMFVGAAANPFADPFEIRVPRLA
KKIAAGVEFIQTQCIYNLEKFELWMKMVRDRGLHEKVYILAGVTPFKSAGMAKYMKNRVP
GMDVPDEVVERMSGVPKEKQPEEGINICVESIQRLKEVEGVRGFHIMAIEWEEKVPEIVE
RSGLYPRPKVE
>A0A1Q4B9A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 62-17|TrEMBL
MNTASVAAKSDPVDATVDQIAAFMRDCSFEATRPSAGDIATLGKTLAPGTQVYLTMLPHR
PLDEMVAAAVAIRQAGLEPVPHLSARHFPRFDVLERHVGRMVDEADVRTALLIGGDAEHG
VGEIQTALSVIENGLFQRRGLKALGLPGFPDGHPNMSEDEIEANLVTKLAAVQQAGLEPH
IVTQFCFDSRTIIAWLHWLRQRGVHAPVRVGLAGPTSLMTWLNYARKCGVKASAEALASR
SGLVRHAFKAVSPDPIIRTIAAAAAAKQIDGVSPHLFAFGGIGATAKWAQPAIAGAIRLN
KDGGFDPV
>A0A2S2FL44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SM17|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVTAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A4S8RMJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda alvinocaridis|TrEMBL
MKVTDHIKKAKGKTLFSFEIIPPVKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTLGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIENV
MALRGDAMKEEKYFAPTRGGHQYASELVKQIHDINGGNYLHEVIETDDCASFCIGVAGYP
EKHMEAPSLQSDLRRLKEKVDLGADYVVTQMFFDNQKFFAFVEAAREMGINVPIIPGIKP
IAVKRHLQLLPQVFRVDIPQDLVDAVDACKTNKDVRQVGVEWCIQQSKELKEAGVPVLHY
YSMGKSDNIKAVAKEVF
>A0A842XR74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MKAGSNLERVFESGKFVVTAEIGPPQSANPEPLVHHAKMLKGYADAFNLTDNQTAVVRLS
SIASAVIVMREGVEPVIQMTCRDRNRIALQSDLLGASALGVRNVLCLTGDHQIFGNEKGA
KSVFDFDSISELQVFDRLRREGKQVGGGEIKDPPKVYLGCAENPFATPYEFRASRLAKKI
AAGADFCQTQAIFDMDLFEKWMDEVRSRGLDKKIHILAGVIPMKTAGAARYMKNKVPGMI
VPNHIIDRMKNAKDSKEEGIRLCVEQIETLKKMRGVHGIHIMAVMWEDIVPRIVEEAGLL
PRPTF
>A0A6V8F3K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MNYRSNLEKRLSEGQFVITTEIGPPKGSDASKIRDKAMMVKGCADAFNITDNQTAVVRMS
SLAGSLILLQMDMEPIMQMTCRDRNRIGLQSDVLGAAALGVRNILCLTGDHQSFGNHPTA
KGVFDIDSVQLLQIIKNMRDAGVFQSGDPLLAQRPCVFLGAAANPYSGSFESQMNHLRKK
IDAGAEFIQTQSVYNVEKFSRWMDEVRSQGLDKRVHLLAGVTPLKSVKMAERMKFHVPGT
DVPDAVYQRMENASDPAKEGYAIALELIRELKSIAGVHGIHITALFWEEIIPALVKDAGF
NARIC
>Q02YT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris (strain SK11)|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYLDKTQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVNLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>A0A0M9DXW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Magnetomorum sp. HK-1|TrEMBL
MNDIRKKFETNSFVTLAELSPPKGTNTETFLNNAKATDGLVDAFLIPDIPNAIMRMSAFS
AACLLQKNQMNSIIQLNCRDRNQLALQADMLGAYANGFDSLMIVQGEDPKTGDHHQAKGV
FDVSLTELFRTAQGMSEGFDLAGMELDGSANFLVGASLELSSKISDRFQIKNTISEYMEA
GVSFFVTQPVFNMQMLAEFYESVKDLKPIILPTILLLKSLGMARYMARNVSTVDIPPELI
KRIQKSKDKNNECLNISRENIASLKELGLHGVVISTIGWEHQLPNILKK
>A0A369AHD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinomonas foliarum|TrEMBL
MKSELATKFQDPTRGIYFIGTTPPKSSLEEEQLAQVSQKLLERLDNIDIDGLVVYDIQDE
TSRIDKPRPFPFMETHDPRAWSKRLHQQSGKPVITYKSVSSRSSEEFSGWLSEAWEQYGI
RDLVLVGSPSSSGDIKLPLPQAYETLKASEHSFNLGGVTIAERHAKKGDEHLRLSKKTEA
GCEFFISQAVYNHQATADLISRYARTCKEKGEAPKRIILTFTPCGSAKTLEFMEWLGISV
PEATKHRILDAEAPLDESIKICRNALEQIIEIALPLGVPLGLNIESLTNRKEEIDASIQL
YKLLKATLDLKLAEQSLIK
>A0A1E5R8Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hanseniaspora osmophila|TrEMBL
MAPVTIKERYAYRAKHYTSPSVSLEFFPPKTETGKGNLINRIRRMTTAFNPMFLTVTWGA
GGTTSEKTLELAALAQNAFRIPVCMHLTCTNTDQEIIDDALQRAKKAGIRNILALRGDPV
VEDNEFMKLDNAYTENTPAFSTNSNLNNNNSNTRERSGSPAPNSKRFRYAVDLVRYIKEQ
HGXYFCIGVAAYPEGHCDNEDLEKQDVMRDLPFLKEKVDAGADFIITQMFYDVEKFLEFE
QLVRTTISSDIPIIPGLMPINNFLTFNRATKLSHASIPQHIIDRFPVELRNDDDIVKSIG
VDIIVEIAETIYARTQGRVNCFHIYTLNLEKSTAQIVSKSALLSTILEEDSSSEEENGEG
YDSDVVIVDDEENDELIELTSVDADKKRKMHKRRRESSSTSYDGPSFMVGAHGNGSQQPS
RKVLVSISQGNGSVGRDATWDEFTNGRFGDSRSPAYGEIDGYGPSLKVSPSTAYQIWGYP
LAEQDLINIFTNYLLGSIPSLPWSDAGLSPETALIQEQLIQLNENGLLTLSSQPSTNGSS
STDKIFGWGPAGGFVYQKSFVEFFVDRNKWETQIKPRLDSFENPQVISYYMGGSNGDFQT
NMQPNSSSVVTWGVFPNSEIQQTTIVEEESFKAWRDEAFSIWMEWSKLFPRNSEQHMFLK
NTYHEFCLVAIVYHDFTNFDGLWDLLA
>W0THR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyveromyces marxianus (strain DMKU3-1042 / BCC 29191 / NBRC 104275)|TrEMBL
MSTVKQRFDALTGPCVSLEFFPPKTEPGKTNLLARMERMCALNPLFVTVTWAAGGTTSGK
TLELATIAQRELNVPVCMHLTCTNMDKSIIDEALKAARDVDIRNILALRGDPPIGEEWDG
NTSQNPSEFKYAVDLVRYIKKNYGDDFCVGVAAYPEGHCEGEADESMQDPLRDLPYLKEK
VDAGADFIITQLFYDVDKFLSFESLVRENISSDIPIFPGLMPINSFLLFNRAAKLSHASI
PQAILDRFPPDVQNDDNRVKEIGVEIMIDIVEQIYKRTDGRIKAFHFYTLNLEKAIAKIV
ANSPTLSKILEDDEDEADDEWGSEAVLQDVDHLTLEDDNMKKRKRQSSASAEFPLNTSII
NKLNGTSGNKLPSMPSRKVMISISQGTGTLGRNVTWDEFPNGRFGDSRSPAYGEIDGYGP
SLKVCNKTAYELWGHPVCLEDIKNIFIRYLEGSMKALPWSDLGLSPETAFIQEELIELNQ
RGYLSLASQPATNGSPSTDNIFGWGPANGLIYQKAFVEIFVHKDEWKNVLKPKIEASDGE
FSYYLGDYTGEFETNLQPNSSNAVTWGVFPNSEVVQTTIVEEDSFKAWRDEAFSIWIEWS
KLFPKNTPENTFLKKMHRDYCLVSIVHHDFHNADGLWEMLLN
>E1W606|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parainfluenzae (strain T3T1)|TrEMBL
MSYANEINTLNQHLADTNKKINVSFEFFPPKNEKMESMLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGIEAAPHLTGIDATPEELKEIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIEAEIVPGILPVTNFKQLQKMASFTNVKIPAWLAKAYEGL
DDDPTTRNLVAASVAMDMVKILSHEGVNDFHFYTLNRSELTYAICHTLGIRPTANP
>A0A0G2FWU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diaporthe ampelina|TrEMBL
MHIKEMVADAEKTAAPSFSFEYFPPKTLTGVQNLYDRMERMYNFGPKFIDITWGAGGRIA
ELTCEMVSQAQAYFGLETCMHLTCTDMGLEKINDALRKAYKAGCTNILALRGDPPRDKEK
WEAADDGFRYAKDLVVHIRKTYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDAGATF
IVTQMFYDVDNFLRWVGKVRARGIDIPIIPGIMPIATYSSFLRRVNHMNCKVPQEFMDAL
EPVKNDDAAAREIGKTLVANMCRKILAAGIPHLHFYTMNLAQATRMVLEELDWMPSERSP
VKQALPWKQSLALGRRDEDVRPIFWRNRNKSYISRTMDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSVKDVATMFVKYLNNELDQLPWSESPLTSEADAIKDDLIE
LNKRGLVTINSQPAVNGVKSSHPVYGWGPSNGFVYQKAYLELLVAPDVYPELISRIEKHP
DLTYYAVTKAGNLATNTPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGTDW
ANCFEAGSPSRILLERMMRDWSLVNIVNNDFHQPRTIFEIMAGLQVKDLDVEVQSDGPTA
N
>A0A022PGE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus aegyptia|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTTEMEKTLWKSINRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGD
LPENGEKPKMYGSDLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQLKRFAVMTNVRIPSWMTRMFD
GLDDDPESANLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A7S0FPW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Minutocellus polymorphus|TrEMBL
DAFGIAVAGYPEGHPNAITDLKPEEVEGMTDSEKKRCSVINGVTAVCRDEDYKKEMDYLK
EKVDAGADVIITQMFFDPDVFINWVKDCRAWGIDCPIIPGLMCINAYAGFKKMVGFCKTR
VPPSLEEKMESMKDDKDAVKQFGIEYGAEVCQKLLDAGACGLHFYTLNLEKVVYGTLDKL
GISSGLLEQSNEKDAASMVAKGSAWCKKGDTVKSSAGEGTVVEIKANGTAIVDIGGETHE
LAKGSYEKLGNAV
>A0A653KRX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 8I-beige|TrEMBL
MSLLAQYFAQQQFCVLVEYLSAHQAQWSVKTEFAGFPAAMALADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDLEQFLKNAKTQDQKNLLLLTGDKLKQHCYSHDLEPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMAAL
QDAHAFLVQHQYAQKMLACVMPLTLARAKFMLKHKVAGIVITPHMLQVLQQEKEQGLSDR
VYVRCALQILMCRHLGFAGVHLSACHQPEEQVFLEGYIEEYRHLSFAECERLWNTLWQVQ
TGTEFHPKLAYYSRPATSSQIIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDRSRAKQ
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTKILKEKLIPTVSIAVRGTSSWKNWYVEAAG
>A0A426D780|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus garii|TrEMBL
MDLKQALQQRVLVADGAMGTLLYGNYGIASAFEALNLTHPDTILRVHQSYVNAGADVIQT
NTYAANRLKLARYNLEDQVTAINQAAVQLAVKARQQADHPVYLLGTIGGLAGDTDQGIQR
ATPPEMRASLREQLDALLATPQLDGILLETYYELPELLSALKLVKATTDLPVITNVSMLS
PGVLRDGTTFNAAIRQLAAAGADVVGANCRLGPYYLAQSFENLTVPTNVKLAVYPNSGLP
GTDQDGAVVYDGEPEYFETYAERFRQLGLNLIGGCCGTTPLHTAATVRGLASRAIVPHRD
RANQPLSQPLTPTKRQHPFLTKVATQKTALVELDPPRDFDTAKFFRGAQRLKAAGVDGIT
LSDNSLAEVRIANATIAAQLKLSYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAV
TGDPAKLGDFPGATSVGDVRSVELIKLIKQFNTGVGPTGKSLKQASDFKVAGAFNPNAYR
TTVSTKSIERKLAYGCDYVITQPVFDLANVTALANALKANDVHVPVFVGVLPLVSKRNAE
FLHHEVHGIRLPRVVRDRMAQAELDGNEREVGLQIAKELIDGICDCFNGVHIVTPFNRFK
TVIELVNYVQQKNLAPTR
>D2TTK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter rodentium (strain ICC168)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVSLLKEVADFDVSVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSFAICHTLGVRPAL
>A0A2H5XTY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR20|TrEMBL
MRILLPNVRGTSPHVLMAIPTFRARLEDARPIVAVGSVEHALSNRTHDRIELVVLQAPLV
LEETMHAFVEAGAELLFTPTERASRLWLAQLDRADRVYELNRKAVWIARKAAAHRAFVAG
TIGPPPTMLHPIGPLSTESLRRAVAEQAIALLDGGCDVLVLKSFIELDELLLAIETVLPL
ANGTPVIALKAFPEDGAVLATSFPADVARLLSQYSLAAIGASGTVGPQRMRGVISAMRSG
SSLPLVALPDTGIPTMVGGRAYYSTDPDYIARTLRELAESGARICGTDRGTTIVHTSATS
QSLAGITQAAPPPVPIQREAHLSARPTVPPPSRFAQKLRERFVITVELDIPRGLDMASVL
DGARYLGMHGVDAVNISDGARARLRVNSLMLSAYVQQETGIECIAHLACRDRNMVALQSD
LLGAALLGVQNILAVSGDPTHIGDYPRATTVGDLDSIGLIRALRMMNSGRDLAGNPLSGT
TNFCIACACNPCAEDIERELDRLAQKVAEGAEAIFTQPMFDLEQWLQFLSRAGSLPVRFI
VGILPLRSVRHAEFLHYEVPGMTIPAWVRKRIAESPNPAEEGITIAAEFLAAVKEHCHGV
YLMPPFKKYDVALSVLERAGVALASRPDH
>A0A1Q6NLZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. 38_16|TrEMBL
MNIREYLENHKLLTDGAMGTYFDTVEKENYICSEEANITNPSLVRQIHKNYVKNGAQLLR
SNTFLANRETLLSLQQKRAEQFQNVSLKELVTKGYRLAEEVAREAYSESYPVFPAADIGP
ILEGKESEETDILQQYYEICDSFLEAGANIFVLETFPDTEYVLKMAEYIRKICPEAFIIG
QFSLTPTGYSRTGFHYKTILRDAVQSGLLDGAGLNCGIGAAHMKRFLEAYIEEYGVPEDM
ILTALPNCGYPQIVRGHVIYSDSVTYFGEKIKEVSELGVRALGGCCGTTPEYIGEIYRTL
FQAEHTLKVPTRIVWTDAAGRIQKRQEQLVHIKSAEGKNKTIKKEQVVNTFRRKLEKGEL
VCAVELDPPFDANDTKLVNGAKELLSTKADIITIADSPLARSRADSSLMAAKIKMQIGMD
VMPHLACRDKNRIAIRSGLLGSYVNEIRNYLFVTGDPVAREDREFTKGVFDFNSIRLMKF
AQSMNQEIFADDTIFYGGALNQNGASPENIAGRMIKKMEAGCSYFLTQPVYDEEGIKRLA
FLKERTGAKILIGIMPLVSRRNALFIKNEMPGIYVPNRVVEKYKENASREEYEEAAVEIS
KEIIEMGKEVGAGFYFMTPFNRVSLVKSILEYV
>A0A7L2KPQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zosterops hypoxanthus|TrEMBL
MVNETQQTSSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWREDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDELERVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYEQRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A444IYU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electrothrix marina|TrEMBL
GGFPNPGYYGRGKPVYDLDSIQVLRLLKDMENGRYPDRTGTRQKQYPAPDILKGCVVSPF
KATEAEQVWQYVKLLHKIRAGADFVVTQVGFDVRKFEELTEFLDEQGIKIPLLANVFIPT
LPLARALSVGKIPGILLSEKLAERMEAEAAAGADNARLDRAALMVSCLKKCGYRGVHLGG
VNLLFQDIAYVLDRVEQLDKEGLPDNADYDFPVPGTWYYFQHRLSDNKEKKAVEPLAPGT
VLGTTWMHKLGHTLFFTDQYVTGRLFARFCLFCAKGRYRFNFLLRLEKTIKRQMYDCQMC
GECTLSHSAFLCPQWHCPKRLVNGPCGGSNQGRCEVHPDRLCFWVRVYNRLDNRTTLASL
VGLPHLPPKDWHREKLHPG
>A0A543I6N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klugiella xanthotipulae|TrEMBL
MNSRVFPGPHHAGATTRWDYVRIEIIPTPGIVDRVAVTFPAHTDITVTCLPQHGITPTVQ
TAIELAGRDFTAVPHLAARQVGSEAVLHDSLDAFAEAGIRTLFIVGGDGRGTGGPYADGG
ELLEAVRAHSGAFYELGVAGYPEGHPHFDVAEGIDLLRRKQVLADFAVTQMCFTPDTLVA
YLGALRAEGVALPIWLGVPGRVRLHRLLAVAARIGVGASLSFARKGSTRQLLRGGHFDSD
AFIARVEAETDQPERFFSGLHFYSFNDLDSVKLR
>A0A1V5TV84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin262|TrEMBL
MRIDTLHQNQDVTLSFEVFPPKTAATYASVIEAVEHLSRRRPDYISVTYAAGGGTSHNSI
DIASRIQNQFATTALAHLSCVSSTRGEIAGIVEQLARNGVENILALRGDIAPGSDFPSGG
NYRYAYELIGDIKKRGGFCIGAACYPEGHAESRNKEQDIEFLKMKVDSGCDFLITQMFFD
NNILYSFLYNALRKGIDIPVTAGIMPVTSAGQIVRMCALANASLPPKFKAILDKFGDRPQ
ALKQAGIAYATEQIVDLIANGIKGIHLYTMNKPDVAGSIVSNLSGVLDIDTR
>A0A2P5SZ57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pantoea edessiphila|TrEMBL
MNDCYVNQQKKLYHSGFEFNKKFKISFEFFPPRSKEMEKTLWNSINFLGKLRPSFISVTY
GANLEEKILTYNVTKNIKDRTGLEVVPHLICVDSTKQELRDIAYNYWNNGIYKIVALRGD
INKASNKPNMYCYELVSLLREVGNFDISVAAYPEVHPEAKNAQADLINLKRKIDAGANSA
ITQFFFNIDNYLRFRDRCVAVGIDVDIIPGILPVLNFKQLKYFARISKVHIPLWMYELFN
DLDHDTETCKMIGAHVAIDMVEKLSKEGVHDFHFYTLNRYEISYSICHVLGIKPYQLS
>A0A2V4UMI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PP-WC-1G-195|TrEMBL
MSGFPNASGDLLPGHSSRGRLEQVLRRGEFAVTAELNPPDSADPEEVYARAAVFEGWVDG
INAVDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQGDVLGAAAMGVANILC
LTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDHAKFLSGRKLTAPPRVFLGAAINPFA
PPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFRAYMEKVRDLGLHEHCHILVGVGPMASA
RTARWIRSNVPGVHIPDAIIARLEGAADQKKEGKQICIDIINEVKEIKGVSGIHVMAYRQ
EEYVAEIVHESGVLKGRRPWRREQDPADAGVAERLDAARGGEMQDQESLAETAAKRPH
>A0A1Q5VEL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia fonticola|TrEMBL
MSFYHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGGGKPEMYAADLVTLLKDVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPDAVVG
>A0A2D4RZJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bermanella sp|TrEMBL
MTMDNFRLSFEFFPTKTEEGTTKLFATRDKLAALNPDFFSVTYGAGGSTREHTVNTVTGM
NAKGIGTAPHLSCVGETKANIKDLLNHYAQNDIQRIVALRGDLPSGMAASAGELKYANEL
VELIRAEHGDKFHLEVAAYPEMHPQAQNFEQDLLNFKRKVDAGANSAITQYFFNVDSYFY
FLDRCEEMGIDIPIVPGIMPITNYTKLARFSDSCGAEIPRWIRKQLEAYGDDSESIMKFG
EEVITQMCEDLVENDVPGLHFYTLNQADPCMNVWKNLGLW
>A0A1V2H2X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas deserti|TrEMBL
MTRVTPVLERWLGGERFAPLPARDVAQPLPLLSFEFFPPRTEALDQQLWSCIERLAPLRP
RFVSVTYGAGGTTQERTHATVARLARETDLVPAAHLTCVGATREAIDDVARGYWEAGVRH
IVALRGDAAPGTDYAPHPGGYAYASDLVAGLKRIGDFEISVAAYPEVHPGASSPEADLDN
LKRKLDAGATRAITQYFFDTGTYLRFLDRCLAAGITAPIVPGIMPVSNFANAKKFSAMCG
TSVPAWLAELFEGTDDAPEIRRIVASIVAAEQVRTLQANGIDEFHFYTLNRPELTLAIAH
VLGVRAPASPPPG
>A0A1B1TUK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. PCC 7117|TrEMBL
MTTRLRRAIENRDFVVTAEVAPPKGGDPTKMLRMAKLLGDRVHGVNVTDGSRAVMRMSSI
AASTLLLQNGIEPIFQVACRDRNVIGLQADLMGAHALGLRNVLALTGDPVKAGDHPKAKA
VFDLESVRLLKLITKLNNGQDFNDKKMPDGPLDLFPGGAVDPQLKSWYTIESRFARKVES
GAQFFQSQMITDFQRLEEFMNRVASQYDVPVFAGIFLLKSAKNAQFINRCVPGAQIPDAI
IERLAQAENPLEEGLKIAAEQVKIAKNLCHGVHMMAVKKEDLIPQILDLADVSIQISTAP
ALV
>A0A4R8CHJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2573|TrEMBL
MANGLPSTRPGGAPTIRELLASGDRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVSHSRDELRSVIGAYAGAGVRNMLALR
GDPPGGPNQPWVAHPEGLNHAVELVELIRSLGDFSVGVAAFPDKHPEATSLEADAQVLAA
KAQAGADYAITQMFFGADDYFRLVDRSAALGCGMPVLPGIMPVTNIKQIQRMAELTGMAL
PEAVTSRLLAVEDDPAAVREVGIEIATELCERLLAGGAPGIHFITLNRSTATRQVFRNLS
SQPTSSSFSSLTTNG
>A0A559T4U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia fonticola|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLDAAPHLTCIDATPAQLRDIATDYWNSGIRHIVALRGD
LPPGGGKPEMYATDLVKLLKDVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVAS
>A0A2A7URZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas terrigena|TrEMBL
MAQNDSTAFPVSFEFFPTKTAEGAAKHVNVRQELYARKPEFCSVTYGAGGSTQEGTFRMV
QAIQDEGVAAASHFSCVGATHAKVREELAQLQTMGVKRIVALRGDLPSGYGLGGEFQYAS
DLVAFIRKEFGDWFHIEVAAYPETHPQAKSPDADLQAFATKVKAGADSAITQYFFNAYYR
FVEGIQALGIQIPVVPGIMPITNSSQLMRFSDATGAEIPRWIRLRLQAFGDDVASIRAFG
LDVVTHLCEQLRSQGAPGLHFYTMNQSTATLELCRRLGL
>A0A3T0K396|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia sp. ICG0124|TrEMBL
MSASEHPSGISFEFFPPNTEVGREKLMGVRDRLAALDPAFFSVTYGAGGSTRERTFNTVQ
SVRSSGICTAPHLSCVGSDRGELREILGEYREQGIKRLVALRGDLPSGMGARSELRHANE
LVEFVRDETGDHFEIAVAAYPECHPQADNYRMDLENFARKMNAGADIAITQYFFNADAYF
HFVERARDLGIQQPIIPGIMPITNYTKLARFSDSCGAEIPRWIRRQLESYADDSESLQAF
GTEVISRMSQRLLDGGAPGLHFYTLNQAGPCLKVLENLGISSR
>A0A1Z8SCC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Endolissoclinum sp. TMED37|TrEMBL
MSASLKQISSLLNGFSTEVTPTSASKIDNFQDHLSLGTSINVTFLAGSNLRDTVQVCKRL
NEEGFNPVPHIVARNFENTMALEIFLDLLVSTADVHEVLVIAGGIGRPLGPFSDSLQILN
SGLLEKYQIRKVGVAGHPEGSPDISKDKLANAIRDKNNWAKNSDMEAYITTQFCFEVPSI
MTWEKNIRRDGNKLPIHIGIPGPATLNTLIKFATMSGIGPSIRVLTRQTKNLTKLVFTQD
PLRIIEGIAFAKLQDPDCLVEQLHFYPFGGLAKTAAWIKDILEKSEFKNLEVG
>A7ZAY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter concisus (strain 13826)|TrEMBL
MLKEKILNKEKGLLLYGLTPPKAEFDEAKLREISERWTGRINDIKADGLVLYEVQDESER
NDSERTFEFSGTLSPEIYYKKYLNVATPSIFYRVASGYGEDEFRTALKAQSSNLNVLVGA
TSSTQKVRLNLARAYEIAGEFEGLAVGGVCIAERHGKKGDEPQRMREKIAAGAKFFISQA
IFDAQLARKFLEDCAAAKISEPIFLTFSTAGNAKTLEFIKWLGVSVPSSVEERLNLSSDY
LASSCEIIKEIWCELKKFGDENGLNLSINIESVMAKRAEIEASLELTKSIRELV
>A0A6S6R0W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerocolumna cellulosilytica|TrEMBL
MRIQDYLKEHKLITDGAMGTYYAKLLNNETAVSEYANLTEPEVVIHIHKEYIKAGAELIR
TNSFAANQQTLKVNKKEQKAIIQSAYKLAKQAVEESGKEVYIACDIGPIPENGDRAEEEI
AAEYKLICDAFLQEKPDIFIFETFSDFFYLKNLIAYIKERAPEVFIITNFTLNKNGYTGK
GISAKVLLETIADTEGIDAGGFNCGIGSGHMFHILKKLRFPDGKYIVSAPNAGYPEQFKN
RMIFMDNEGYFEGNMQRIVDLGVDIIGGCCGTTPDYIKKIADNIDLKEEERGIRFRFLED
DTKELTYEKNDFYSLFTRNKKVVAVELDPPFDAKDDSIIACAHKLKASGAHIITMADSPM
GRSRVDSILMSVKLMRETGISVMPHVCCRDKNMIAMRSGLLGAYINGVRNILVVTGDPIP
SEQRQSTTGVFDYNSMQLMNYINEMNREHFLDDPIFFGGALNYGRGPVDKVIERMKKKIQ
AGAGYFMTQPIFADEDVDRIRYIKSKVNTKILCGIMPLVSYRNANFIKNEITGIHVPDWV
VERYHPDMSKEEAERVAALIANEIIEKLSPFADGYYFMLPFNRVSLMDKIVIK
>A0A6P1NNW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter psychrotolerans|TrEMBL
MFPTRIEIIPSTGIVDQVRALVPLTTTLTMTCLPHHGIERTMRTSVELSALGYTVIPHLA
ARSIHDRAELTRIMRECDAAGIGEVFVIGGDRKQPAGPYGSALPVLEDIAQYTGGRMRAG
VAGYPEGHPTVAALDLLDALQDKQHLATHVVTQMCFDAPKILDFAALLRREGVDLPVWAG
VAGSVPRTKLVALATQIGVGSSLKFLSRKGPLARKLLSGDRYSPHPLVAGLESQPGIAGI
HLYSFNNLDAVPNEAGLASSPTALQPALIRGAAREQ
>A0A6V8N926|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomonas limicola|TrEMBL
MKIVDQMNQGKQFLSLEFFPPKEKNEWPNFFKVAERLTRLNPLFASVTYGAGGSSQGDTL
EIVTRLKREHGLESMAHLTCIGANHAALRQFLDELASAEVYNVLALRGDLPQDAGPEVSV
CRTLSHASDLASFIREAHPEMGIGVAGYPETHPEALSPEHDLACLQKKLELGGDFVITQL
FFDNQSYFDFVARARALGVEKPIIPGILPVVSLKVIRRIVSLCGASIPPEFLARLEEADR
AGGAAAVQKLGIAHARHQAEGLLAAGAPGVHLYTLNRDQAILELVDGLLPA
>A0A843ZJD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium meliloti|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKMRDLGLHERCYILVGVG
PMASAKTARWIRSNVPGIHIPDSIIKRLEGAQDQKKEGKQLCIDIMNEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLRGRKPWTREAAPTDALVAERLEHIREGKEENQQQMAEAAAH
HPH
>A0A519KHJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTDHIQKANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFAPPFIDVTYHREEYEYKE
LPNGLLEKKIVKKRPGTVGICAAIQNKYQVDAIPHILCGGFSKEDTENFLIDMDFLGIQN
VVALRGDAVKSEIYFKPERDGNQFATELVSQIANLNRGIYLDEDLQNSAATNFCIGVAGY
PEKHVEAPSMDSDMYFLKQKIKDGATYIITQMFFDNKKFFDFVAKCRKEGITVPIIPGLK
PLSTKKQLNQIPHRFHVDLPDDLIMSIVRAKDGDAVRQIGIEWCIAQSKELVAAGIPVLH
YYTMGKSENIREIAKAVF
>A0A1G3IJ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax sp. RIFCSPLOWO2_12_FULL_60_11|TrEMBL
MTATPQIPLSFEFFPPKTPEGVEKLRVARQQLYALKPEFCSVTFGAGGSTQEGTFSTVRD
ILAEGVGAASHISCIGATHAKVREQLAILKAMGVKRLVALRGDLPSGFGIGGEFHYASDL
VAFVRAETGDYFHIEVAAYPEVHPQARSPEADLQAFATKVKAGANSAITQYFYNADAYFR
FVEEADALGLSLPIVPGIMPIASSTQLMRFSDACGAEIPRWIRLRLQGFGDDAASIKAFG
LDVVTDLCEQLRAGGAPGLHFYSMNQSAATLEVCNRLGQGPAD
>A0A292PSQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tuber aestivum|TrEMBL
MEKVVDKIAALPPGEPYHSLEFFPPKTSMGFQNLQARLERMAHALRPLFVNVTWGAGGST
ATKSLQLAEICQRQLGLTTVLHLTCTNMSQVVLDETLETAKEIGIRNILALRGDPPRSGD
YHDTPCDGTSNGVGNEFEYAIDLVRYIREKYGDYFCIGVAAYPEGHVEGACPEKQDPLFD
LPFLVEKVKAGADFIMTQLFYDAEKYIWFERLLREEPSGVLSELPVIPGLMPIQSYSMLK
RITKLSGASLPAGILRRLDDVKGDDEAVKQVGIDIVSEIIEGIKVANLSGPRGFHFYTLN
LEKAVSFIIERTNLIPPPDEPVLEEIEGPVVNGASLRRDRRTSSVTSDPHNRVIVDDSSS
LQSPRLANALEAGFLKPPEQSRPPEVALAISEGEGALGREATWDDYPNGRFGDARSPAFG
EIDGYGPSLHLSQSQAIKLWSYPVTKRDVSDIFVRHIRGELEAIPWSEQGLSVESGIIAD
YLVRLNQKGFWTVASQPAINSVKSTDEVFGWGPKGGFVFQKAFVEFFCSPDDWGVLGAKL
GGVEDISYYAANKNGDYAASVPLGDSAMHAVTWGVFPGKEYKEIVAPTIIEEVSFRAWKE
EAFTIWKEWARVYPPRSASSKLMMEIAETYYLVNIIHHGYMDSEFLWKLLEV
>F8FVA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida (strain S16)|TrEMBL
MLPEERLMSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTL
NTVLQLESEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGE
LRYASDLVEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFF
NADSYFYFVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDT
ASIQAFGEEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>E8R5X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B)|TrEMBL
MHIRDILDRHSTTFSFEFFPPKTPAAWEELFVTIRELEPLQPSFVSVTYGAGGTTREKTH
ELILRIQHETNLTAVSHLTCVCHTEAELAAILDRYAESGVENILALGGDPPRSMPDHRRE
QDAFAHAEGLVRFIRSRTKLPDPRGFGVGVAGFPEGHPACPNRLKEMDYLKAKVDAGADY
ICTQLFFDNRDFLDFRERCELAGITVPIIAGIMPISTKAGMIRMAELALGARFPAKLLRA
VERCGDDDEAVNEVGIHFATEQCLDLLENKVRGIHFYTLNKSDATRRIFKNLGIKNSSVF
HSKSSRSAAVESGLTLTAHVG
>A0A4R4BQB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp. J25|TrEMBL
MRISLEIVPRNEDELVREAKLCEKWKSITHINIPDLLRFPLRSWEGAALLHQENVPLPVI
PHIRAIDFDMRRDFPLKEFFMQHDIQTVLVIAGDPPQDMGRRVYPTKTTELIRKLKNELP
SLTVYAAFDPYRANIRYELDYLLAKEDAGADGFMSQPFFDERLLEIYAEYLENKRVFWGI
SPVLSERSKTYWEIRNRAIFPKNFEPTLEWNVRFGKKVIAFCKTHGFDLYVMPIKVDLTS
YLEALLG
>W6VYG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. (strain CF080)|TrEMBL
MTADSETFSVSFEFFPPKSDEMEGQLWNTVDELALWDPRFVSVTYGAGGSTKAPTINTVR
RLVGETSLATAAHLTCVDATREETHSVVGDYRAAGIRHIVALRGDPASGIGTEYRPHPQG
YANAADLVRGLTELGGFDISVSAYPEKHPESADLAADIEMLKRKADAGAARALTQFFFDN
DVFERYLEKVRAAGIAIPIVPGIMPIQNLSQLKRFAGRCGSSVPSFLDARFEGLDDTPED
RANVAADIAAEQIEDLIRRGIDDFHIYTMNRAPLVSAVLQKLGRRQIRTPRTAAA
>E0MLQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ahrensia sp. R2A130|TrEMBL
MSDAIYSGDISGKPVVSIEYFPADGLIKERALATGAHALRRFDPDFQTVTFGAGASPVDG
SVEWSTRLSQLTEVPTASHLTLCTFPTKAELFAFTDELWQAGIKHLVVLRGDAASDDGGL
GEFESVADAVRALRKRRGWEISVSCYPETHPKAESRAADIAVLLDKQRAGANRAMTQFFF
DNDDFYAFRKEARDVGVTIPLVPGIMPILNAEKIFSFAEDCGAKVPAGLRQRFEACGDDK
AKRSDVAREFVQEQVRDLAQNGVKAIHVYSMNRVDLTADAIRAFQACFDGRETRAKLRLV
S
>A0A0P7CN69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. R43|TrEMBL
MGSVEARPREERRPATMSDFLASGVTSYSFEFFPPKTPDGERHLWTALREIEALRPSFVS
VTYGAGGSTREGTVRISERIAAETSLTPIAHLTAVNHSRAELRQVIGGYAGAGIRNVLAL
RGDPPGDPLGEWVRHPDGFTHADELVAFVRSLGDFCVGVAAFPDKHPRSADLDADARVLA
GKFRAGAGYAITQFFFEADDYFRLVERLARLGRDEPIVPGVMPVTNVAQITRMAQLSGAA
FPPALARRLEAVAEDAAAVREIGIEVATALSARLLAGGAPGLHFITLNRSTATRDVYRNL
LGSAAGTAA
>A0A1T4U920|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterovibrio nigricans DSM 22720|TrEMBL
MGYSHASHLDALNQNLSDLNGDINVSFEFFPPSTESMEQTLWASVQRLKTLQPKFVSVTY
GANSGERDRTHSIVKSIKQETGIEAAPHLTCIDASRDELKTIARDYWESGIRHIVALRGD
LPEQGKKPDMYASDLVALLKGEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIIPGILPVSNFKQASKFAKMTNVRIPHWMNKQYD
GLEDDPVTRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGIRPSL
>A0A257DH00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium PASS1|TrEMBL
MILPFAQMQEASRALAAPLFAGLAGDCEISFEFFPPKTEKMEEQLWDSVVTLAPLAPRFV
SVTYGAGGTTRERTHNTVARIARETNIPAAAHLTCVEASKGEIADVANAYWEAGVRHIVA
LRGDAPGSDGKFVPHRDGYASAAELVEGLRKLHPFEISVSAYPETHPEALSAASDIDFLK
RKLDSGASRAITQFFFEPETFFRFRDAVAAAGVDAEIVPGIMPVSNFGAITRMSAMTGTA
IPVWMAHLFEGLDDHPSARQLVAATVAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GKRPSGAAQEQAA
>A0A2E2XQN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maricaulis sp|TrEMBL
MSADGSTIQPRNGLNVSFEFFPPKTEAMEETLWESISRLEPLSPNFVSVTYGAGGSTRDR
THRTVRRIVRETGIRPAAHLTCVSATRDEIDDVIRDYWSAGIRHIVALRGDPPDGIGEAY
TPHPGGYANAAELAAGIRKIGDFEISVGCYPEKHPESRDFDYDIDLLKQKIDNGATRAIT
QFFFEPDVYFRFRERAERAGITIPIVPGIMLQANFNGLKRMAGLCGASLPAWLHEAYDGL
DEDAGTRKLVTAHVAAKLCSKLQAGGVDNFHFYTLNRAELALSTCQLLGVKAEQREAVGV
A
>A0A7D5P0L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccales archaeon|TrEMBL
MKAGSNLEAVLSKGRFAVTAEIGPPKSASAEVIRRHARVMKGSADAFNLTDNQTAIVRLS
SIASGVVCLQEGLEPIIQMTCRDRNRIAMQSDILGASALGIRNVLCISGDHQSFGNQKEA
KNVYDVDPVQQLMIFRRMRDEAEVWGGDKLEEPPKLFLGAAANPFADPFEYRARRLAKKV
AAGADFIQTQAVYDVGRFESWMRQVRSMGLHEMAHILAGVMPIRSHKAALYMKNKVPGMI
VPDEVIDRMKKASDQKAEGARLCLEQIEHLKGIEGVHGVHLMAVAWEEIIPEIVKDAGLL
PR
>A0A7V5NYU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfatator atlanticus|TrEMBL
MGFRESLKDPDTFTVTYELVPGRSTRRREFRNIITFVKEAARDKRLHGVSITENAGGHPA
LSPEVLGREIKALGLDPILHFSCKDKNRNQIESTLFARDREGLHNLLIITGDYPRYGFMG
KAKPVFDLDAVHLLQMITEMEKGFTLPPEAPGGGVRLPPMPFFKGCVVSPFKRYEAELLP
QYFKLNRKIAAGAHFVITQVGFDARKFHELLLYMREERLNVPVLGGVLVMDQRLARIIYR
GVIPGISISKEFLERIEREEKQMGHQAALIRAAKLMAVLRGLGYDGVHLCGAKPVYDEIA
FVLDKAEEFYPRWQEFLPEFKDTPPDTFYLYRKDPKTGLNLPERNKRADAPRLPLSFCLN
RLFHDLFFEPD
>A0A8F9T027|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Se5.02b|TrEMBL
MSSETETSGTPRVPFSFELYPPRSESSEEALHETVLRLAAAGPDFLSVTYGAGGSTGGRS
LDVLRFIRERTDVEPLAHLTCVGNTYAGAATLIREFLDAGILSFLALRGDPPVGQTEGYL
GDLESAAQLVQLIDRVQAERAPYEESPVPGFPRAARVDPRRKVNIAVAAFPKGHPRATHR
TQDVEALLAKQAAGATFAITQLFFHPDDYLAFVERARAAGVSIPILPGIMPITSPARLKR
VLELTGEDLPSELAIALDVEPTAQGRREIGIEWAARLARDVVAGGAPGVHLYAFNQHETV
LTVLAEAGILPALRH
>A0A533REU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTAADRRRQLLERLHHGPVIVGDGAMGTQLHQLGAPPDAVFEYLNLIDAPLVGRVHAAYA
AAGAELLETNTFGANALRLGAYGLEAKVAAINRAGVRLAREAAGPARFVAGSVGPLLPAR
GGGADPDITTRRAVFAEQMTALAEAGIDCFLLETFPAVADLQLALGIARELDVPAIAQLA
FTEGGFTGDGLSAEQAAQQLTAAHPAAIGANCGAGPRELLLVLRRLAAATDLPLTAFPNS
GFPERIDGRTFYLATPGYFAALGREMAEAGAALIGGCCGTGPGHVQALAEALRARRPGSR
VRPVAVTAAAPPAGPATPAERRFLAPWGSRPLVTVELDVPKGLDVTTTVARARQLAEAGV
DAFNLAENPLARIRMSNIALASRLQNETGVEAIPHITGRDRNLLGLHSALMGAHLLGIRS
VLAVTGDPVAIGGEAGAGNVFDLNSVGLLKLIDALNHGRTLYGAELGASAGFVAGCAFNP
NVADLSGQLHKLEKKLAAGARFVQTQPLFDPQLLERMMSAVRPLGVPVLVGLMPLVSERN
AEFLHNEVPGIVLPDAVRQRMRGTTGSAGVREGMAICRDLLTEGKRLGVGGYYLIPPFGK
VELALELIGAIRG
>A0A7W6C1Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium fluoreni|TrEMBL
MTDVIEAERSANPAANASPYSDLPGDIAVSFEFFPPKTEKMDSQLWEAIGDLAPLVPSFV
SVTYGAGGSTRERTHATVSRIVRETNLKPAAHLTCVAASKGEIGEIADQYWDAGVRHIVA
LRGDPPPADGGRFVPHPDGYASAAELVAGLKARHDFEISVAAYPEVHPEAASAAHDLDNL
KRKLDAGASRAITQFFYSTDAYFRFLDKALAAGIDAPILPGIMPVTNFAAIRRMSGNTEI
PPALETLFEGLEDRPGPRALVAAVAAADLCRRLYDGGVRNFHFYTLNRAEQTYAVCQLLG
VRPTENA
>A0A7C5QBB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNENRKSLKEKLEEGKFVVTSEVGPPKGANISRMKEHINSLKDVVDAINVTDNQSSVMRL
SSLGGTCIIKEMGGEPVLQVTCRDRNSLAIQSDLLYAFSRGIVNVLCLTGDAVVVGDHKN
AKPVFEMDSVSLLHLLRKLEEGFDFGGNKLDGKMSFFKGATVTPEARPVEPQMIKFEKKI
DAGAEFFQTQAVFDIDTLKRFMDRARKFDVKILAGILLLTSVKMANYLNKNVPGVVVPEE
IIEELQSAGKGEEKKKGMEIAAKMIRKIKEEKICHGVHIMAIGMEGIVPEILRMSGVI
>A0A7V9LD68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSAVSSVRSGSSGETSDHDERSRMKPLAEAIESGPLLLDGAMGSLLYERGVLHTRSYDEL
NLSQPDLISAVHRDYVNAGAELVETNTFGANRMALARHGLVDQAGDIIRRGVALAREAAG
DRAYVAGAVGPTGAKFGIASASERKLARFALAEQIDTLVLAGVDAIMLETFSSILEMETA
IGVAKERGPRVPVLAMMVFDAAGKGDGGLGPAEIADRLIAAGADVVGGNCGIGPAELYQV
AVGMVGRGKPVIAQPNAGLPASVEGRTLYVANPEHFGVFARRMLKSGVRVIGGCCGTTPE
HTRSMLGAVRMLRGEKIDERGPKPSVIEVREIKPHAAAKVPLGDRSRMGSRLARGEFVVS
VELTAPANSDLSKTKQQVNELVAAGADIVNIADGPRASARMANIAVCARLAAETKVEPIL
HVCARDKSFLGLVAHLFGAQALGLNNLVIITGDPPKMGDYPFSTPVYDVDSVGLLRIASG
LNAGVDPAGKPCEPTSFTLATGAEPGAHDRDRELRRLEDKKAAGAELVMTQPVYDPRTLE
RFLDDMAPLGLPVMVGILPLASHRNAEFLHNEVPGMSIPTEFRERMAKVGSGAAARAEGI
AIAREALAGVKHRVQGVYVMPPFNRVDSALAVLEVVRDRWKPGA
>A0A7C3XTJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSKLERILTAGHFAVTGECGPPRGANVEVMRQKAAHLKGVVDAVNVTDNQTAVVRLS
SLAGCLILMQEGLEPNLQMVVRDRNRIALQSDILGAYALGIRNMLCLSGDHQRFGDHPSS
KNVFDLDSLQLIQTVYRMREEGKFINGQDIDTPPKMFIGAAANPFADPFEFRAVRLAKKV
AAGVDFIQTQCIYNLDRFEKFMEQVRDMGLDEKIFILGGVTPMKSVGMANYMKNQVPGMD
VPDAIINRMKGVAKKDQAKEGIAIAVETIQRLKEMKGIAGVHIMAIEWEERVPEIVEMAG
LLPRPEI
>A0A7C1MR98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTLKEKIASRKFVVLGEFEPPKGNDFSRLTENANQVKGRLDAVVVPEMANGVMKASSLGG
CAYLKEKGLETVLQVCCRDRNRLALQADILSASALGISNLMAVPGEDIRFGDHPQAREVY
DLDLMELLEAMGKMREGRDMAGIELMGSPAFFTGSTLNAGAIGGALDIEIKNLEKMLKRG
VEFAITTPVFDLHRFRQFLKRVDMDRVAIIPTVLLLKSAGMARYIDRNIKNVSIPPEMIR
GIQKAPDKMKQCIGIAAELINQFKDLKMAGVMISTVGWEDKLPQLLDTAKI
>A0A8I1ZHG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLLKNILSCTPTTFSFEFFPPKTDTAWEHLFHTIADLMPLSPSWVSVTYGAGGTTRENTH
RLVVRLNKQTDLTVVSHLTCVASTREDIHAILDHYEANGIDNILALRGDPPAGQTRWTAA
PGGFRYASDLVSFIKDHFPRMCIGVAGFPEGHPETPNRLREIDYLKAKVDAGADFIITQL
FFDNRDFYDFRERCELAGITVPIIAGIMPIITRSGMIRMAELAAGSRFPAGLLRALNGAR
SPEDIERVGVEWATDQVRDLLENSARGIHFYTLNNARATLRIYEGLGLSGACRTGA
>A0A3N5TA27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLKRKFETGEFAVLAEMEPPKGVDVVTMVANAKRVKDKVDEFVVPEMSNAVMRMSSLGG
AMVLRMEGLPASIQVCCRDRNRLALQGDLLAAYALGISSVMAVRGEEPSFGDHHQTRPVY
DIDLIELLKAIQGLHAGRDMAGIELAGAPDFMVGSTIDAGAKGKSPDLEVEEMMKRFEAG
ARFFITPPLFDTAAIEPFLKRIKRPEIIIIPTVLLLKSLGMARYIARNMPHIHIPEALIE
RLQRSPDKARECIQIASEMVVTLKREGFRGVFMSTIGWEHKLPEIIEGI
>A0A495KAR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia muralis|TrEMBL
MDTTTDGPDAFTEYRGTRSRECPKRMVFGPCGGVRDDSTCEMDAHICPFAVLTEPIPWPQ
PLTSPASPSELINASRTRPVVLSDLSVPAFDRGVLEQVASILGESSDAVLVGEHQNRPDY
PPTVMAQIIRGVGGCPWVTLTCRDRNRVVLEQELMGLGQAGADGVFCVTGDGRAQGVRQD
VTQVFDLDGTRLAALAAQADLAVGVPEAPEAVPTGIRPARLLEKQRAGAQLAVLNHVSTP
ESLRAFMSAAREQGVTMPVIAGVAVYTDERSAQVLAAFPGLHLDHSQITRVLAADDSVEA
GIETAVDEAVALLDIPGVVGVNLSGLASAAGEVPAAKVKAEIGRRLRERLADGAQSVKAA
QW
>A0A661M6R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
VTSEVQAPLDESPDQLVKSLELIRGRMDGVTIPEIQIEGIVSDTIKVCELLNENRFDAIY
QTTTRDKNRIQLQKDLLRAHNSGVENLLVFTEDYRITGDSLQEMMFFHVDAGKLQSVLQH
MREGRTVDGHEIEKATDFVVGSGVESGWGKDVPDLELKEMEALAEIGVGYFLSTPVFDVD
QFARFLKQVDTFGIPVIAEVMILRTAGMARFLNRHIKSGMVPEWLIKKLAEAPDKEKASI
EIFADTVKGLKDLCQGVHIITIGGEKKLRYYLDAATLR
>A0A509LET1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSFQKRLSAGKFVILAEMHTPKGVNISKMVLDSRRIKGRVDAVIVPDMDNGVMKMSALAG
GVLMHQQGLETIIHVYTRDRNSMALQGDILAAHVLGIQNLVVVHSEDMANGDHRDAQPVY
EVDEPGLLEAIQTLQSGKDLAGFDLDGVPSFTSGCAMGSFANDADMESELQLAQKKVAAG
AQFIITPPVFDVEIFADFMKKTTGLGVPIIPTVFLIKSVAIARYIAKSEPEAHVSEAMIK
RIRKASDREMEGIKIAGETVKALSKIAQGVKIQTLGWEHRLPQILDVAGL
>A0A427HDZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia rettgeri|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSEEMEQTLWKSIDRLKNLKPKFVSVTY
GANSGERDRTHSIIKDIKDKTGLIAAPHLTCIDASPDELKAIARDYWNNGIRHIVALRGD
LPDNSRKPDMYAVDLVELLKGEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATSIDVEIVPGILPVSNFRQLERFAKLTNVRIPAWMSKMYE
GLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A534RI77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKIRQLYGRGGPVISFEFFPPATPAGEAALMRTIEALKPLGPGFVSVTRTGTKPREAPVE
LVTRIRALGIEAAAHVTCIEASREEIAAHCDLMVGRGIENVVAIRGDVPQDPAFRRPANG
FRHAVDMIRFMREGGHGFCLVGGGHPEGHPECRDLDLNIEHLREKVDAGVDVVITQLFYD
NADYFAFVERARRVGIRVPLVPGIMPITNWPQIERITTLSGNQVPSRLHAALERVRNDEP
AAVAVGVEWATRQCAELLRGGAPGIHFYTLNKSPATRAIFENLRREGLLGR
>A0A661Q739|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSLKSKFETGEFAILVEAEPPKGVDISPMLAHAEPLKDKVDAFVVPEMSNAILRMSALGA
AIALQNKGLETAMQISCRDRNQLALQADLLAAAACDINNIIAVPGDDPKIGDHPQTKAVN
ELNLVELLQAAKKLQQGNDLGGNPLSSAPSFLLGTVANAGMTGKNLTKEIDNSKECLTAG
AQFIITPPLFDIAAIEPYLRQIDHKTTKIIPTVLLLKSVGMARYIKQTQDNVVIPDGIID
RIRKASDKAKTCTDIAKEMLESLKQKGFAGAMISTVGWEHKLMEILKP
>A0A534SYB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKITDILARGGPCISFEFFPPKTPEGEAALMRTIEALKPLGPGFVSVTRTGAKPREAPVE
LVTRIRALGIEAAAHVTCIEAGREELAAHYELIEARGIENVVAIRGDRPGEGSFHPPLNG
FRYAADMIRFVRARGHKLCLVGGGHPEGHPECRDLELNIQHLKMKVDAGLDAVITQLFYD
NADYFAFVERARRAGIGVPLVPGIMPITNVPQIERITALSGNQIPAALRAALERVRDDEQ
AALAVGVEWATRQCAELLRSGAPGIHFYTLNKSPATRAIFENLCREGLVGGPLPRLATPS
PIR
>A0A534WAS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRICDLLRFAGERGEPVFSFEFFPPKTEAGVEALFETVRQLHPLAPAFVSVTWGAGGSTR
GRTLEMVTRIKRELEIEAMAHVTCAGATREELRAAVESVMAEGIDNVLALRGDPPRGQPT
FVPTEGGLRYASELVQLVREVSEAKGRPLCIGGACYPEGHVETRDLQADLRNCKKKVDAG
AQFLITQLFFDNRCYFDFVGRARAAGIEVPIIPGIMPITNVEQVQRFTAMCGAHVPAKLA
AAMKVRKDDPEGALQLGVAHATLQCADLLRRGAPGIHFYTLNRSPATRAILAALRASEPW
LDA
>A0A355H976|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MHLIELYQKQDFVYSIEIFPPKTEKGMEKLKITLEAFRSSAPDYFSVTYGAGGTSRENTH
ELSAYIQHELDVPAMAHLTCVSHTAKEIDDVLTKLKNSKIENMMALRGDPTAGTERFIQP
KGGYRYAVELITAIREHSDFGIGAAGYPEGHVENPDIDNDRKHLHEKIATGAEFIVTQFF
LENTHFLRWRDKLHHEGANVPLVAGILPPSNWKATKRMSEMCGVNIPQDLSESLIKYENE
PQTSREIGFEHVEQQIDELLAEGVEGVHLYALNSLETVKRLGPKLRDAASTSSSLPAD
>A0A1C2DB70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas xanthomarina|TrEMBL
MTSANRPSISFEFFPTKTEAGHEKLLATARRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKQELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKARAGASSAITQYFFNADCY
FYFVERVRKLGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMDSIQA
FGTQVISEMCEKLLAGGAPGLHFYTLNQAEPSLAIWDNLGLSR
>A0A179GI75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Purpureocillium lilacinum|TrEMBL
MDKITDKIAALPPDAEYFSLEFFPPKTAMGFSNLRHRLQRMEQALRPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRRLIDKALEDAKVLGIRNILALRGDPPRNEE
YRDADDTDDGAAEDFTWAIDLVRYIRSKHGDYFCIGVAAYPEGHADESHPLGQSLEHDLP
YLVDKVQAGADFIMTQLFFDIDAYDKFEKTLREHPSGAFKDIIIMPGLMPIQSYQMIKRT
TKLSHAKMPEAIMSRLNAVKGDDEKVKLVGVDIVSELIEQIRTIKSRSTGRKGFHFYTLN
LEKAVAFIVERTGLIPDTSDNEEAVVEDTSAAPTLQVNGNVRLRTRSHSRTSRRQSSVGS
DPHNRVIVGSQRPSHPEWEASGQEAGVPAEAINSRANTLAISEGEGVLGREATWDDFPNG
RFGDSRSPAYGEIDGYGVSLHMSVASAVRLWGHPKTRQDISDIFVRHMKGQLEAIPWSEE
ELMPESSAIQPRLVELNSKGWWTVASQPAVNGLPSNDSTFGWGPPNGFVFQKAFVELFIP
SSDWKVLAERLRAPEVRDVVCFYSANAKGEFESSDVSGAANTSTGEASTNAVTWGVFPGK
EIVTPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLNGIKEDYWLVNIIHHDFVD
KEALWKLLMA
>A0A356HZ67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLTLRDALTSNRFVITAEICPPKGTDTTAFIKNAQLLKNRIAAANVTDNQRAVMRLSSLA
CSVLLLKEGIDPVFQMTCRDRNRIALQSDILGAWTLGISNILALSGDHVSFGDHREAKPV
FDLDSVQLVQTISKLNNARNMNDTSLNSGTDFLIGAVVAPEANPLEPEMIKFEKKVLAGA
RFFQTQAFYDMENFKRFYEYAKRFDVKILAGILLLKSAKMAHFLNKNVPGVTVPTNIIEE
LESAPDQLEKGIEIAARQIRELKTFCDGAHIMAIGQEENVPKIIESAN
>A0A2N2HC39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-21|TrEMBL
MTEKETGFQARLRSREQVLVVEVAPPKGGDPIPLRSAAKRYQGKVHAISVSDNRHGICMA
SLAAGAILASEGMEPIVHVLTRDRNRIALIADCLGAQALGVRNILCTSGTHQTLPGCSQA
RNVFDMDSTQLIEAIAHLGNNGSMFLGERFEPAGPFCLGAVAAPFADPAELQLIRLAKKV
NAGAEFLITQPVYDLDRFRTWWGQVTKRSIHEKSAILASIQPLLHAGSAKAYAESRPTPR
VPRSLLDRLSSAGNAEAERAAGIDIAVETIKQVSALKGLAGFQICADGDEGAVLEILERS
GLEVR
>A0A496YI05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEYKSGSNLEKVLKAGHFAFTGECGPPQGANVEKLREKAQHLKGMVDAVNVTDNQTAVV
RMSSWAASLILLQEGLEPNFQMVCRDRNRLAMQSDILGVYAHGIRNMLCLSGDHQKFGNH
PQSKNVYDIDSMQLIHMVKTMRDEGKFLNGEEIDVPPRLFIGAASNPFADPFDFRVYRLA
KKIEAGADFIQTQCIYNMDKFREFMKRVVDMGLHEKCYILAGVTPMKSVGMARYMAKQVP
GMDVPESLIKRLKGAGKGKAAEEGIKFAVEQIQEFKEMEGVAGVHLMAIEWEHRVPEIAE
MAGMLPRPTV
>A0A1G3ACQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RBG_16_64_12|TrEMBL
MAKEKTDLHQRIDSGQQILLAEVSPPPGGDPSPVREAAARYRGKVHALSVSDNRDRVSMS
ALAAASLVREAGVEPILHVVTRDRNRIALVSDYLGARALGIGNVLATSGTHQTLSRARAA
KNVFDVDSIQLLRTYAGLAGDARLVGEKGLDGCGPVCLGGVASPYADPLELQMVRLAKKV
DAGARFLITDPVFDLERFDRWWNEVTHRGIHERVAVLVGIRLLWGAEEARAFAARRPDPR
VPGVLVERIAAEEGKPAQRTAGIAIAVETVERLSGTRGLRGFQICGAGDDEAALEVIEKS
GMGIDLPCR
>A0A534VD51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKITDILARGGPCISFEFFPPKTPEGEAALMRTIEALKPLGPGFVSVTRTGAKPRE
>A0A2G6NSD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLVKDILKNREISFSFEFFPPKTEKGFENLFKNIEKLKKLSPSYVSVTYGAGGTTVGRTH
DLVEKISKELDITVVSHLTCSGSSCNEIHALLKNYSEIGISNILALRGDPPLNEKIFKPH
KDGFNYASELVAFIKKIFPDMCVGVAGFPEGHPETPNRILEMEYLKRKVDEGADYIVTQL
FFDNRDFYDFCERCSFYGINIPIIAGIMPVTSKKGLQRIAELAAGARIPAPLLKAVEKAA
DDEGVANIGAHWASEQVRDLMYNNVKGIHFYTLNKSPATIKIYKSLGNLSSSNFL
>A0A661RLP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTESKLEKVLASGALAVTSEVGPPRGALPDKVRQKANLIKDHVDAINVTDNQTAMVRMS
SWAGCAIIKQMGLDPILQMVTRDRNRLAMQSDIIGAYSLGINTMMCLSGDHAKFGDHPMA
KGVFDLDSIQLVQTVKKMRDEGKFQGGADINTPPKMFIGAAANPFADPFELRVMRLAKKI
KAGANFIQTQCIFNLDKFEKYMEMMCDRGLDEQVHLLAGITPMKSAGMARYMKNKVPGMD
VPDEVIKRMAGVSKEEQPEEGIKIAIESIERLKQIKGVHGFHIMAIEWEEKVPQIIEKAG
LFPRPVV
>A0A4R1U771|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. PP-CC-3G-468|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGISFEFFPPKSERMDAQLWEAIRTLEPLQPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPVDKVAAA
>A0A2T5NLL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium sp. Panama|TrEMBL
MTAQSRTFSFEFFPPKTPEGIAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLATVLEI
RSEGHAAAPHLSCIGSTRENIGAILKEYRNNGIRHIVALRGDIPSGMVAAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDIGNFVRKVHAGANSAMTQYFFNADAYFRF
VDEVQGRGVNIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRQRMQAYYDDSASIRALGL
DVVTELCDRLLQHGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A661S3R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLTTLFDKNEFVITGEVGPIKGAISRDKSIEPICAIEALQLQQHVHAVNVTDNQSAVMR
LGSLAASVRLQTNGIEPVYQLTCRDRNRLALQSDLLTAYSLGIDNVLLLTGDHIQLGDHK
EAKPVFDLDSVQLCEMARGLNNGSDICGNSIENNMDMALGAVVNPNFEPLDLQLMKMKKK
IDAGAEFFQTQAVYDVKLFEKFIKKAEKFNCPIQVGIVVLKSPQMGKFMNKNVSGIQVPD
EWIDEIGSVAKEDHKKKAAEMAGRFIKEVKSMVQGVHIMPLGWADIVPDILEHAELN
>A0A0A7JRN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas parafulva|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMAVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALIAEYKAAGIKRIVALRGDLPSGMGMASGELRHASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEDDLANFVRKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDSASIQAFG
EEVITALCDELLQGGAPGLHFYTLNQAEPSLAVWQNLKLPR
>A0A3M1X6U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKIREIFLKGRPLLSFEFFPPKKVENEHILEETVGHLKKYSPDFVSITYGAGGSTRAKTL
EWTLRLKDVHGLNVMMHLTCVGSTRSEIDSIVARLTQEGVDNILALRGDPPRESGSENPW
KDFRYAFELVRHIKKKGDFCIGVAGYPEGHIESPSLEKDTEYLKMKVDEGADFIITQLFF
DNRFYFRFRERTERAGITVPILPGIMPIINLGQVTRFTEMCGASVPQSLIREMEGLSPED
TLKKGVDFAIAQCEELIREGAPGIHFYTLNRNRATEMILEELGDFRGRESGPSNSPKEGE
G
>A0A496YHY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MVSNFKKALESGKFVVTCEIAPPKGTNLDKMRHHIELLKDKVDATNITDHQSSVMRYPSL
GGALLVKECGGEPILQMTCRDRNRLALQADLLFAYSRGVNNVLCLTGDSVIFGDHKEAKG
VFDLDSSQLIMAIRRMEKGKDLGGNELDGKVQFCVGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVYDLDNFRKFMDYARQFPVKILAGIILLTSAPMARFMNKNVAGVNVPQTLID
EMASAPKGKTINKGIEIAGRMVRQIREEKICDGVHIMAIGREELVPEIMAAAGLL
>A0A661J8W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSSSRLERVLTAGHFAVTSECGPPRGADPEAIRRKGELLRGVVDAVNVTDCQTAVVRMS
SLSSCLLLKEMGFEPILQMVTRDRNRIAIQSDILGAAALGINNILCLTGDHQRAGDHPQA
KNVFDLDSVQLIAAVKAMRDEG
>A0A8I0Y0F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSAGMSLRADAFINAFSLEVSAKAMPALRAEAVRIPRGTIISIPWLASEDDDARLAAART
VRELGLEPMPHLSARRIGSHAALERFLERATGEAGVTRCLLIAGDLATPVGPFADSASII
ETGLLEHFGIKVVGIGGHPEGHPVMSADDRWEVLGRKCQGIEARGMAPLVVTQFAFDADT
VLAWLDALRARGITAPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVKGLTDAHGPISPHFFPFGGIAPSLEWIAQYQRRVRGSGR
>A0A6L9MT14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas hispanica|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVSAVPHLTCVDASREELKQIAQDYWDSGIRRIVALRGDLP
AGVDTTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIS
QFFFDTSVFLRFRDRAAAAGVDLDLVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRGDNK
>A0A644XG17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MKISTLLSQGRPTLSFEVFPPKGDGEFSSVRNAAVQIAALRPDYMSVTYGAAGSGASFYT
GSIAAAVQEQGLSALAHLTCVNSTRQEVRLQLAALRALGIENILALRGDLPAGMDPDAPR
DYRFAADLVADLRSLGDFSVGGACYPEGHVECASQTEDLRHLKDKVAMGCDFLITQMFFD
NSILYSFLYRMQAAGIHVPVIAGVMPVTNAKQICRIVKLSNASLPHRFRMIIDKFGDDPA
AMKQAGVAYATEQIVDLIANGVNGVHVYVMNKPDVAAQITANLSEILRR
>A0A644ZPE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MPVLAHLTCVDSTGEGVADQFNALQEAGIENLLALRGDVMENSKPKDAWSCRYASELAGA
AKDYGGFCVGGACYPEGHIESASLREDVENLKKKVDAGCEFLTTQMFFDNNILYNFLYKA
REAGITVPVVAGIMPVTNAKQIRRITSLSGTALPQRFLHIVDRFGDKPTAMLQAGVAYAT
EQIIDLYANGIRAVHVYSMNHPQVAETIQANLSAILS
>A0A6E8VSF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles coluzzii|TrEMBL
MATTNTVTNEEQSNEDSLHTKLDRIFNSSTTSGPVPVHYSIEIAAKDDFDIGQLERLTPQ
PVFCALPWVSDDNLRYADDFLRSPTLQLTARLRENQYTVLNNVSCYNITEQQVDQLLRST
GIRNLFVIRGDTVSPGQQFRNSAGLVQYLRKWQEQQPDHRQLTIAVGGYPYGHHQSSSQT
EELHYLRAKISQGADFLLTQTLYDAPSFLRYRDRCREAGISIPIIPGIYVPHSYRHLQAL
LNLTRIELGPTVRDAFEAHANDAPDQFQAFMVEYFVGVVRELLQPNATTSSDPIKLVHFF
TFNKFHLLQQVLGKLDEFFK
>A0A5P0YF08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fictibacillus phosphorivorans|TrEMBL
MSLITDLEQNKILIGDGAMGTLLYSYGSDFCYEELNLSQEEQIYNIHRAYLDAGADIIQT
NTYAANYSKLERYGLQDHVKEINKAAVHIARKAAHNEYVVGTIGGIRGIKPNSISLDEIK
RSFREQLYCLLMENVDGIQLETYYDLEELETVLEIARKETSLPIIAQVSLQEVGFMQNRT
SISDALTRLENLGADVVGLNCRLGPYHMLMTLEEVPLPKRAYLSAFPNASLPSYTDGRFK
YEGDADYFKECAHLFRRQGVRLLGGCCGTTPAHIHAFSSELKNLKPVTEKIVKQRKQKIV
IQTASKPKYVPLSEEVKKKQSIIVELDPPRKLDTSRFMEGAKALNEAGIDALTLADNSLA
SPRVCNSALGSIVQSQLNLRPLVHITCRDRNLIGLQSHLMGLHTHGIHEVLAVTGDPASV
GDFPGASSVYDVTSFELIKLIKQFNEGLSLSGKELGEKTSFTVGAAFNPNIRSIDKAVER
LEKKIAYGADYFISQPVFSEQRLIETYEATKHIDKPIYIGIMPLTSSRNAEFLHHEVPGI
KLSDSVRDRMGKYKDDPKQACEEGLLIAKSLLDTAMELFNGIYLITPFMRYELTVELAQY
ARANSPSLLARRSQNA
>A0A2J0U6Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSAGTSLRAQAFINAFSLEVSAKAMPALRAEAARIPPGTIISIPYLASEDDDARLVAART
VRGLGFEPMPHLSARRIASRTALERFMGRAASEAGVERCLLIAGDLATPAGPFADSASII
DTGLLEQSGIKAVAIGGHPEGHPVMGSDERWQALQRKCQGIEARGMAPSIVTQFAFDADL
VLAWLEALRARGITVPVLVGVPGPASIPRLLRYAAMCGVGASASMLARYGVSIGRLLGTA
GPEVFVDRLVQGLTDAHGEVSPHLFPFGGIAPSLEWVERYRAGVRAARV
>A0A261C7W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis latens|TrEMBL
MTNAGGTHVAETQETIKKIDSLSTMPYCGIDTDDNSGVEERATLETGKSWSPKHYELLHE
RIERLIDEKQPFFSLEFFPPRFVNGVPNFLERVERLSEGGSVFVDMTWHMGSDPANIDKV
TSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPGTEL
QDTHQFRALDMIRWIREEYGSYFSIGCAGYPLGHPQAPSYKADLMYLKAKCDAGANFVIT
QLFFEPETFEKFVRDCREIGITQPIIPGIMPIMGYESIKRIATLSQLEIPQHILDDLEPI
KHDDDAVQKYGTERCIAMCRRLLDNGSAPSIHLYTMNREGSIREILKALGLWKLEGDRVF
PWKNRSQHPIRCLESVRPIYWSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLS
NLTTLRNGDDRLSMFGDNIDSIEDVKRVFINYITQTPNAAGKKVTVLPWTEAETGVQPET
SLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSEK
LIQIIQRDFPIRVNYHAIDKDSTFDQTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRA
WRDEAYQMWMAQWGDFYPKESKSYGVIKSIHDTFRLVTLVDNDFQKPSVLFDVLQTALEE
LRK
>A0A1R1J336|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia ubonensis|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTGLCQRLLDAGVPGLHFYTLNSAAATRTICERLGA
>A0A428IN24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVANDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVGETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A644VLH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MSVIEKIQSAGGKTAFSFELLPPLKGNGIETVYRTIDTLREFDPKYINITTHRSELVFRE
KSVGLFERVAERHRPGTVAIAAAIQNKYKIPVVPHIICSGFTREETEYALIDLQFLGITD
LLLLRGDKGKHEKEFSPTGHRYATELQQQVNKFNQGFFLDGSQMKSKITPFSYGMACYPE
KHEEAPNLESDLYYAKMKVDAGAEYLVTQMFFDNQKYFDFVAKCKENGIHVPVIPGIKPI
TLQNQMTVLPKIFHTDIPEAFATELRKCKSDAEAVEVGVEWCIQQARDLIAHGVPSIHFY
SMMATQSVKRVAQAVY
>A0A1V5TBV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium ADurb.Bin269|TrEMBL
MKISEILQTNKLTVSFEIFPPKQDSAYDAVIGCADELVRFDPDFMSVTYGAGGGTSANTV
KIAAHIKDRGITSIAHLTCLSSTTSEVHRIIGELKDRNIENILALRGDRPKDPDFVPPGD
YRYASDLIRDIRESGNFCVGGACYPEGHPESGHKDRDLDNLKLKVDAGCSFLTTQMFFDN
NMLYSFLYRAQSKGINVPVLAGIMPITNGAQLKRTIELSNAYLPPKFLALVDRFGDSPEA
MKQAGIAYATEQIIDLITNGVRGIHIYAMNKPDVVQKIVSNISDIIKAAK
>A0A3B6VVD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira hyodysenteriae ATCC 27164|TrEMBL
MSDNSVENFIDKLENKDEYTFTLEISPQAKFDLGYIKDKIDDAKISDYIDAFVVTDSPFA
NLKISSILAALQLQQRLNNNKPFIATQTMRDKNSIALQNDLIGANYFDIRMVLAVTGDPI
NGGNQKQAKSVFEGNSELLIAIIKDLNKGKSLGEFAFKEPLKPIYSFCVINSYAKNNDSL
KVRLAKKANSGVKAIFTQPIYEAERLELLLEWIDELPLKNKPILVPGFFPVLTYKTAYFI
YYKLPGAYIPEDWLNKLKKASNKSPEEEKRVAVKLSSDLFHNMLKKHKKMHIMSMNNYDF
VVNLLKNIK
>A0A173MPK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Filimonas lacunae|TrEMBL
MKITQHIAQAKDTLVSFEVLPPLKGKSINSIYDHLDPLMEFKPSWINVTYHRSESMFKKK
ADGTFEKVEVRKRPGTVGICAAIMNHYQVDAVPHIICGGFNMRETEDALIDLNFLGIDNV
LALRGDAPKNEASFDAEPGGHNYAIDLLKQINNLNSGIYLDEDIQNGGKTDFCIGVAGYP
EKHFEAPNPEIDLRYLKAKVDAGAGYIMTQMFFDNQKFFAFVEACRKAGINVPIIPGLKP
LTSKKQLSVLPRIFHVDLPTELSNEIMKCKNDSECEQVGTEWLIQQSKELKEYGVPVLHY
YTLGKPKVVRDVVKQVF
>M7Y2N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariniradius saccharolyticus AK6|TrEMBL
MKITEYIQQASKTLFSFEILPPLKGQSLKELCEGIEPLMEFKPPFVDVTYHREEFIYKKH
PNGLLEKISTKKRPGTVGICAALMNRFQVEAVPHLLCGGFTREETENALIDLNFIGVQNI
LALRGDAPKSEGKFIPEPDGHAYTKDLVKQIVGMNQGRYLHEETETGFHTDFCVGVAGYP
EKHFEAPNLKSDLRYLKEKVDAGAEYIVTQMFFDNQKFFDFTRKVREMGIDIPIIPGIKP
ITTLSQISMLPRTFFLDLPDALMDELEKCKTNAEVKEVGIRWAIQQSKELVKHGVPVLHY
YTMSKADATYRIAKEVF
>A0A0B9G394|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium gaetbulicola|TrEMBL
MGYSYASHLDSLNQNIADIDGNINVSFEFFPPSSEQMEQTLWNSIHRLKTLQPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLVAAPHLTCIDATRDELRSIARDYWNNGIRDIVALRGD
LPAQGGKPDMYAADLVELLRSEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGACRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNMKQAKRFANANNVKIPGWLEKQYE
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAKA
>A0A1H0FSL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium sp. OV277|TrEMBL
MTIHELKAKPMTKIAASIEVAARQAIESQDLPGLFPEGTRVYITDMGTDGVDTLTAAAKR
IHDLGYKPVPHFASRRLGTKVALETRIRRAAEEAGVTDVLVIGGGLERQAGEFSSTMEVL
ETGFFDKYGINEMGVAGHPEGSPEFSEAVALEALRLKKNFGERTGARLRVVTQFGFDADR
FIRYAESLREHGVDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNALSLTALATSH
SPEGVVGPIEQHVINHPASAIKQIHIFPFGGLKKSSEWLVDRGSWNVATGHYASAAAN
>A0A0K9YTN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus reuszeri|TrEMBL
MTTSKVGLREFLHDNLLIGDGAMATQLHRLGMPVGVSFEELCLSNPQLVHDVHASYYQAG
ARFLETNTFSANRDALARYGLEHKVARINRLAVAIAREAAQEDAYVAGSIGSILAGRVRK
KVLDEYRDQYEEQAIALLHAGVDGLILETFVDLEELLLALEVIRPLTEAPLIAQLATLEV
GRTRDGYSLTEAFAHLKAAGADVVGLNCRLGPAEILRSFEQVQIPINTILSAFPNAGRLG
MTDGEYAFKSTPDYFAESALRLREQGVRLLGGCCGTTPEHVQAMATALQSLEPLERVNPP
IVTGDTPSITVQSARLHDKPSIVERVKTGTTIIVEFDPPRDLDAEQFLHGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKNRHGIDPLLHLACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPARFGDLPGSSSVFDVTSFDLIRMVKQLNEGISFSGRPLKQKAQFIVGAAFNPN
VRKIDAAIARLEKKVEAGADYIMTQPVYDAESIKLVYESTKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSDEALARMKSVQGAEARKEGIAIAKELLDTAIRYFNGIYLITPFNYHE
MAAELIQYVRQQSALVKAVAQP
>A0A852VHU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edaphobacter lichenicola|TrEMBL
MADEVRSAELASVAGYAAAGRLFDGATVLCDGAMGTMLYARGVFINRCYDELNLSQPDLV
REIHNEYLQAGAEVVETNTFGGNRFRLGQHGLQDQVRAINVAGVKLARECVNQIREKQAC
EAFVAGSIGPLGVRLEPLGKVGLEEAQDAFAEQIRAMVEGGPGVGVDLLIVETMTSLTEA
EQAILAARRVAPGVRVVVMMTVDEDGNCLDGASAETAAIKLTEWGADAVGCNCSAGPATV
LSVIERMRPLTTLPLAAMPNAGIPRAVEGRTIYLTSPEYMASFTRKLVKAGASIVGGCCG
TTPSYTRAMKSSLRALDAMESGVEVMQRDATGNATTIKESKVAPPPLAERSKIGSMVAAG
DFVTMVEIVPPKGIDCSKELDGAMQMHRLGVDAINVPDSPRASARMSAQSLCVQIQQHVG
IETILHYTCRDRNVLSIQSDLLGASSIGLKNILCLTGDPPKLGNYPNATAVFDVDAIGLV
NVVKNLNYGLDIGNNSIGESTGFSIAVAANPGVQDMDQEVRRFAFKVEAGAEYAITQPVF
DLRVLEEFLRRIESFRIPVIAGIWPLTSLRNAEFMKNDLRVSMPDEIMARMAKALTPEAG
RLEGVKIAQEMLAEAKPMVQGVQVSAPFGRYGVAADVLGLAAVEVA
>A0A823HRS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes CFSAN003726|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDDVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A7X8KS09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MKTLELYNTKSILSFEIFPPQGSDPLTAIHNTVQKLKELNPDFISVTYSAGKSENKANTF
EIASVIKNHYGIESVAHLPGLHLSKRAVLKILDYCKCSGIENILALRGDTNPALTPHNDF
RYASDLISFIKENGDFNIIGACYPEGHIESPTIIEDIRNLKNKVDAGADQLITQLFFDNN
SFYSFRERAVIAGINVPIKAGIMPVMSKRQTERMVALNRIKLPKKFISIMNKYENNPEAM
RDAGIAYAVDQIVDLITQGVDGIHLYTMNNAYIASQIYKAINTLLVA
>A0A851IVV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptostreptococcaceae bacterium oral taxon 081|TrEMBL
MKISDILSKNKVNLSFEVFPPKSDVALGAVLDTVRDIADLKPAFCSVTYGANGGTSGNTV
KIASYIENELNVCALAHLTCVLSSKEDIDEKLQKLKEHNIDNILALRGDIIDEEAFKNKK
DLIHSSELMSYIKDNYDFCIGGACYPEGHLESKSKDEDVEYLKLKQDLGADFLTTQMFFD
NNIFYNFMYKLRNKNVNIPIIPGIMPVTNVTQLKRIKQLSGAQIPPKFLSIADKFKDDVP
AMKQAGIIYACNQIIDLISNGINHIHVYTMNDSDIAKRISDNLSYILEK
>A0A7W8IGC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edaphobacter lichenicola|TrEMBL
MADGVRSAELASVAGYAAAGRLFDGATVLCDGAMGTMLYARGVFINRCYDELNLSQPELV
REIHNEYLQAGAEVVETNTFGGNRFRLGLHGLQDQVHAINVAGVKLARECVNQIQEKQAC
EAFVAGSIGPLGVRLEPLGKVGLEEAQDAFAEQIRALVEGGPGVGVDLLIVETMTSLTEA
EQAILAARRVAPGVRVVVMMTVDEEGNCLDGASAETAAIKLTEWGADAVGCNCSAGPATV
LSVIERMRPLTPLPLAAMPNAGIPRAVEGRTIYLTSPEYMASFTRKLVKAGASIVGGCCG
TTPSYTRAMKSSLRALDAMESGVEVMQRDPTGKATIIKESKVSPPPLAERSKIGSMVAAG
EFVTMVEIVPPKGIDCSKELDGATQLHRLGVDAINVPDSPRASARMSAQSLCVQIQQHVG
IETILHYTCRDRNVLSIQSDLLGASSIGLKNILCLTGDPPKLGNYPNATAVFDVDAIGLV
NIVHNLNYGLDIGSNSIGGSTGFSIAVAANPGVQDMDQEVRRFAFKVEAGAEYAITQPVF
DIRVLEEFLRRIEGFRIPVIAGIWPLTSLRNAEFMKNDLRVSMPDEIMARMARALTPEAG
RLEGVKIAQEMLAEAKPMVQGVQVSAPFGRYGVAADVLGLAEVEVA
>A1AKP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelobacter propionicus (strain DSM 2379 / NBRC 103807 / OttBd1)|TrEMBL
MNILERLKGEVLTGDGALGTMLYARGVGLDSSFEQLNLTRPALVRELADDYVAAGAQVIE
TNTFGANYTRLAALGLEQRVWEINLAGARIARQAADQGRDVLVAGSVGPLPRIRGDEAES
DQERMAELFRVQCQALAEGGVDLLLLETFSSLTQLAAAVQAARCTGLTVAASMAFLEGGR
SADGATVEEFCAAMERAGADLVGANCGAGPLELVKVVRRLAAVTHKPITAYANSGFPEYH
DGRFIYRATPEYLATMAGELVAAGASLVGGCCGTTPEHIAAISRALSGRCPASRAGAAAV
RVGEPEQRPSSSGGSFLDAWGRRKLITVELDPPKGLDCSRIIEGCRRLKRAGVDAINLAE
NPLARPRMGNIALGSLIQQQVGIPVIIHVTGRDRNLIGMQSDLMGASLLGIRSVLAVTGD
PATMGDHAGATSVFDLHSLTLIKLLADLNRGVNAMGNPIGGGAGFTIGAAFNPNARDMAG
QASRLRKKVANGAMFAQTQPIYDAGLFFQALELTADCAIPLIPGIMPLVSQRNADYLHNE
VPGISIPETVLARMCGLEKEAGVAEGLAIAREFIDASFHSSGGYYLMPPFGKVELALDLI
EYIHTKEREPSCGES
>A0A7Y8Q6I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. SwsAc4|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRIVHQELQRLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1Z9JB94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium TMED167|TrEMBL
MNDPLHSLPVESSLVRRLLGGEFALTAEVNPPVSASPTELLEKSAPLKGLVDAVNVTDGA
GARVHMSSMAAATILNANDIEPVVQLTCRDRNRIALIGDLLGIGALGMHNLLILKGDDPT
AGDQPQAKPVFDLQSAELLAIAHEMTARGLIPSKTAKLTNEGVEPNTKAXSTPPKFFIGA
ADMPTAEIDEKWLAGLRKKQACGTRFIQTQLNYDMNIVRQYGQXLVDEGFAEHMXFLIGN
GPLPSARSAIWMRDNLWGVVVPDDIIRRLDQAEDPKAEGIEICAQQLQEMAKMPGVAGVH
LMAPINVPAIPVAIERANLPR
>A0A0W0LQI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas marginalis ICMP 9505|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLHNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>E2S0L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium pseudogenitalium ATCC 33035|TrEMBL
MSPRLSASAPLDYESEEEAPAPERLALSFEVIPPRHDADAAKIDRLLEVLESYHPDYIAV
TSSQRSGWLEGTAAFIEKISQNTSMRPLAHLACTAGTRDELIGWINRLVDAGVRGLLALR
GDLPEGGMPEHYLQHADELVRLIRQLESHQAARFAAGRLAVSVACYPSGHAESKNEDEDF
DVLLNKQRLGADFAITQLFFDAEDFLRFAQRAKLAGVKIPLIPGIMPMTSLRRLERMGQL
SGLTVPERVRNQLAAATTPEEEYEIGMELTAQLARTIVAGGADGLHIYTHNNPDITQDLL
SRIGVDNDDH
>A0A3M9N172|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rufibacter latericius|TrEMBL
MKVTEHLQKATNTLFSFEILPPVKGTSIQSIYQGIDPLMEFKPPFINVTYHREEYVFKER
ENGLLEKITIRKRPGTVGICSAIMNKYHVDAVPHIICGGFSREETENALMDLNFLGIDNV
LLLRGDAVKTEPGFRPHKDGHSYASDLIKQVVQLNHGQYLDEEMENPVPTDFCIGVAGYP
EKHMEAPNLSTDLRYLKHKVDLGADYIITQMFFDNRCFFDFVKACRAAGITVPIIPGLKT
LTTRNQLNVLPRYFNIDLPEDLVNAVEACTNPKDVKQVGIDWTIQQCKELMDFGVPCLHF
YTMSKSDATVAVAKAIF
>A0A133XGL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dechloromonas denitrificans|TrEMBL
MNTEISIEFFPPQTPEGVDKLRTVRAELAKLKPSFFSVTFGAGGSTRERTFSVVKEIAAE
GFDAAPHLSCIGSTRASIRDILADYKAAGIRRIVALRGDLPSGMAETGEFRYANELIEFI
RAETGNWFSLEVAAYPEWHPQARSPKDDLEAFVRKVKAGANSAITQYFYNADAYFSFVDE
AQALGANLPIVPGIMPIVGFTKLARFSDACGAEIPRWMRKKFESYGDDADSIRAFGLDIV
TELCERLLKGGAPGLHFYSMNQSALTTEICRRLG
>W4F5F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Viridibacillus arenosi FSL R5-213|TrEMBL
MGLLEKLQTQVLTADGAMGTLLYSYGIDYCYEELNITKPEVIENIHQQYIKSGADIIQTN
TYTANAIKLERYGLESSVKEFNESAIAIAKHAAAPGGQFVLGTIGGIRGIRKSEATLAEI
IAALDEQAGYLLAGNPDGLLLETYYDFEELSSVVQHLRKLTDVPIISQVSMHEPGILQNG
LLLNDALHQLEALGADIVGVNCRLGPHHTIQAFEDVELPSKAFLSAYPNASLLDVEDGKI
VYESEADYFGRAGVLLRDQGVRLIGGCCGTTPKHIEAVKKRIADLPPIENKIVKKKKVIE
IKEATPDQHEPLHEKAKKERTIIVELDTPRHLDTTAFIEGAQILNETGVDAVTMADNSLA
SPRISNMAMGSILKMQNNIRSLAHITCRDRNLIGLQSHLMGLDALGINEILAVTGDPTKV
GDFPGATSVYDVSSLELLQLIKQLNEGISFSGKPLRKKANFSIAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVYTKEKIIEIYEATKHLETPIFIGIMPLTGIRNSEFLHHEVPGI
KLSDEVLERMRATGNDKNLATAEGIAIAKELIDTAAELFNGIYIITPFTRYDMSVELIHY
IQELDQQKVGDHNYVKTTN
>A0A7Y0HRP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium muellerianum|TrEMBL
MSLLKEAFERGEFAITAEMAPPKGIDLSHLIECAKAIKGRAHGVNVTDFQSATLKATSLA
TCKVLKDAGLEPVLQITGRDRNRIAIQGELLSAGVFGIENVLALTGDYTMTGDHPGAKPV
YDLDSVGILNVASTIAQGKDMAGNDLNGTPEFYLGACVTPRYDPLELQILKMDKKIKAGA
KFFQTQAVYDIETLKMFREKTKHLDAKLMVGIIPLKSAGMAKYMNKNVPGIFVPDELIER
MKGAENKVQEGIKISGEFIKKVKDEGLCDGVHIMAIGAEENVPLILDQAGL
>A0A1M5E461|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jatrophihabitans endophyticus|TrEMBL
MLTGDTACPKRMVFGPCGGVRPDGACEMVAMPCVFPEPVLRPDRVAGVAPGTAPRVLADV
SSPPFDVAGLRRVATLLRDSSDALLVGEHHNRPDFPPTVVARILQDEGCRPWITLACRDR
NRVVLEQELRGLQLSGVDTVLCVTGDGRGPDVRPDVTQVWDLDGPRLAELAASLGLCAAV
PETPTAPPIVGRPARLAAKERSGAGIAVLNHVREPGQVARFMAQAHAAGLTIPVVAAVAA
FTDAESAAALQRLPGLELDPEVVAAVLASADPVAAGISAAVDEAAALLAIDGVVGVNVSG
LASSRGWDHAAEVKAAIGARIKELVV
>A0A1J5DVR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desantisbacteria bacterium CG2_30_40_21|TrEMBL
MSKQFKDVLASGEFVITSEIGPPKGTNIEKMLHHIEILKDKVHGMNVTDNQSSVMRLSSV
AVCHIITDHGGEPILQMTCRDRNRMALQSDLLSAYVLGVRNVLCLTGDHISLGDHKGAKQ
VFDLDSVQLIAAVKSLEAGQDIGGNKLDGGVEFCVGATATPEADNMDSQFLKFRKKIKTG
AGFFQTQAVYDMVKLKAFMEYARQSDVKILAGILVLVSAGMARYLNANVAGVTVPQELID
EMAGAEKGKALQKGMEIAARQIKQIKDEKICDGVHIMAIGKEEVVPEILSMSGV
>A0A074U4D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioclava dalianensis|TrEMBL
MITPNVSFEFFPPKTLDASFRLWETAQLLAPLKPSFTSVTYGAGGTTRKLTHEAVGAIHK
NYGLNVAAHLTCVEATKAETMEIVDAYAEVGVSEIVALRGDPPQGAKGFTPHPEGFASSV
ELIEALAEDGRFTIRAGAYPEPHPDAADPMADVRWLKRKVEAGATSAITQFFFEADTFFR
FRDACEKEGITAKIIPGILPIQSWKGAKKFAQSCGTSIPAWVEEAFEAALRDDREQLLAT
AICTELCDKLIEGGVEDLHFYTLNRPGLTRDVCHALGVMPDTVLENVA
>B3EDH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium limicola (strain DSM 245 / NBRC 103803 / 6330)|TrEMBL
MLVREILNSASEPVFSFEFFPPKKDEDWETLFETIANLNHLHPSYVSVTYGAGGSTRSRT
HDLVTKIQKETGLTVVSHLTCICSDREDTASILENYLEHGITNVLALRGDKPAGIATLND
AIKDFPHAIDLIRFIKTNYPAIGIGVAGFPEGHPETPNRLKEIEYLKEKIDAGADYIVTQ
LFFDNRDYFDFVDRCRIAGITVPVIAGIMPVSTKKGMIRMSELALGARIPAPLLKQVLHA
RNDVDVAKIGIDWATAQVQELIERQVKGVHFYTLNLADATLKIFRNISIG
>D8PBG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira defluvii|TrEMBL
MIREPRRLKDVLAQGQFAVTVEYNPPKGTNLTHVVESAKALVGRVHGVNVTDNTAAIVRA
GSLPVCRVLYELGHDPVMQLTCRDRNRIAMQSDLMGAHILGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVTGLNNGKDYAGNKLDGSTAFTIGGAVTPEADPLGPMLVKFEVKV
RAGAEFFQTQAIYQPEQFKTFMQAVRPFNVKVLAGILLLRSAKMAEFMNANIPGVCVPQD
MIDEMRAAGDKRALDAGVEIAVRTIKAVRPYCDGVHIMAIKSTERLPEILTKAELG
>J1R9N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. JVH1|TrEMBL
MTFDSVRGRASEGWVTRTPSIVDRIRSSSDGRVPFSVEFSPPRDEAAEARLWRAVREFER
MGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWEKHPDGVEYAEDLVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSV
RRVLELSGSRLPAHLEKRLATAAGDGPEENRAAVREIGIDVATEMSERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSGVADPAPVTPARVS
>A0A2A9DN30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium renale|TrEMBL
MCATALAASDKIAGDSAIFSRQAMNTQKWARLALSFEVIPPRNPDDRSKMDHVVETLTAY
NPDYIAVTSSLRSRWLEGTSALVKHLTEHSRVRPLAHLACTAGTEAEIRDGVQELIDAGV
RGFLALRGDLPEGLDRLPEGYLQHATDLVASIRELESEQACRFAGGNLAVGVACYPAGHA
ESENWEEDIRILKLKQDTGADFAITQMYFDVEQFARMLTDARAAGVTIPLIPGIMPVTSL
ARAEKMAQLSGFELPSHIRAALEAAGPENEYEVGMELTAQLAAQSLAAGAGGLHIYTHNH
VDVTVDLLDRITT
>A0A1A3N6B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium asiaticum|TrEMBL
MPAELGCPKRMEFGPCGGVRPDGQCEMRAGACAFDDVVPWAGPVSDERLTARPHLPPLVL
TDFSCTPFDRADVAATASILAPACDAVLVGEHQNKPDFPPTLMGALLLDVGVAPWITLSC
RDRNRVVLEQELRGLKSIGVDTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGVT
PAVPETPTAPPVHGRPMRLVEKQRAGAGVAVLNHVPFPKMIQDFMTTARSAGLSIPVIAA
VAVFTDSVSAAVLQGLPGLELDPAVTEEVLTAADPVSAGISAAVAEARALLSIEGVEGVN
VSGLASASGAHIGAEIKAEVGRRVREEAR
>A0A7V8NSF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Acidoferrum panamensis|TrEMBL
YSEEGTTHGDIRPSDAASQLKNKNVQVIGANCTLGPQALLPILQELAAVDDIRTSGMPNA
GFPKREGDRIVYPKSSPQYFARFAREAAALGVRILGGCCGTTPAHIQAMAEAVKSLRPAK
AHATSPVAVEAVAKAAPVSHREPESRFWKKLKKREFAICLEIDPPKGLALDRIFEQVDKV
MASGKVDAIDINSGAMARVGMDALVVAGALEARGVETIPHLTTRDQNIIGLQAALLGAWT
VGGVRNVLAITGDPPSVGDYPETSGVYEVDSVGLVKVLNRLNQGTDWAGKTLGGATNFAI
GVALNPVADDLDNEIARFHAKVEAGAHYAMTQPLFDPEHWHAFLKKFGEKPPIPILIGVW
PLNSYKQALRLNNEVPGMVIPEALLKSMEAAGAAARDCGFQVARQMLAWARTELAGAYII
PPFKRYEEILEIL
>A0A7V8NX38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Acidoferrum panamensis|TrEMBL
MNVINPLRESLSAGRFCYVVELVASRLTREARLLEVASKLAQVPGVVAGSITSYAGGAIG
HDPVRVGTAARARGLTPNIHLTCVGRDRTAAWRTLEDLRALGIENVLALTGDYPKAAGLE
PPEALFDLDSVQLVRLIDEARQRGMPFWISVAVSPFKYTEADCAYQYLKLQKKIAAGADC
VITQLGYDMRKFRELKRYIDEKAIQRPVLGNVYVLSGKAAEKMSKGEPPGCWVSPELLER
IRTEIKEADNGRAARLERAARMVAVLRGLGYAGAYLGGDHQADHVRWIIRRSEALDSRWQ
ELEEEFSYAPKNGFYFFQGNFAPAKKRGLLPRSLDQMARLFPVNQDGLLRNFLVRLFRIV
DKRPWLAHAVERFEFAVKSPLWGCQACGNCVLSYMEYVCPQTCPKNLRNGPCGGTNNGQC
EVVDKPCIWVAVYERAKSAGRIADLQPYVPPPRRDLKRTSSWVNYFLGRDSRPGNILSTI
VPLAALLPHEDLGRGASGYAPKTVSEANSKVPAVKINAKRE
>A0A840P169|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermocatellispora tengchongensis|TrEMBL
MALGRPSRLPGRVPTIRELLAAGDRSFSFEFFPPKTDAGERQLWRAIRELEALRPTFVSV
TYGAGGTTRDRTVDVVERVAHETTLTPVAHFTAVNHSVRELRHLIGRFAGAGVRNILAVR
GDPPGDPMGEWVRHPEGVLYAEELVRLIKQSGDFCVGVAAFPYKHPRSPSIESDTEYFVR
KCRAGADYAITQMFFRAGDYLRLRDRVAAAGCDTPIIPGIMPVTQYSTIARSEQLSGAPF
PAEVAARFEEVKDDPAAVRRLGIEHAAELCGRLLAEGAPGIHFITFNRSSATREVFRRIQ
PATASISA
>A0A0W0YHV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Legionella santicrucis|TrEMBL
MWKKSNKYFEYRKTIPVYLLGDKISLTTDFVKNLFDKNFKVIVKKIDDIHQMDPLYFGNE
CILIKSTDESDQSLKFKEKGYSAVKVPNEYLGLKSTYEIQHINYSPALADHISSLEIFSL
RQFEKYKTPPDNVAKIYIANFEKSLDKDVKKAIVNAKERGKKPVPYLPVRKYTENEARSL
LNYFKTQNIDEVVILAGGNFPGAGEMLVVNNQTGKFPQWLEELKINDAYPEWMKVTTEGE
AIRSDTGELPHWLGISSTGILEDKRFNNTSEFLKCINLNEYGIKEIGIAGHPEYSKFMNQ
AECMNSLLEKEKIITQRGMSMYIITQVIANPHKFVTWQKAVRQQGIQSKIYIGLLVPDAE
AYHGRFYKICEALTRNPDKSEYDPEGIYRVDNALNTPEKVWEFLLLSGVQVDNIHLYTVS
VPPEQTKINGITSVAVNNNSIDQIDFEELRVKHKKMAKFAFKAPWFKESLHNNVKTSVDD
LQFQSTQELKRTHVFFRSVKTRYAADDVCANDRMRIKL
>B3M3Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila ananassae|TrEMBL
MHWIPIPNVNSDPPFAKYQPCVTFTDDQTIEKQNLEEQRVGPLVVKKTAERKFFYGIEIM
APSPSGQPVVLDFNNFLPVLPSFVSLVWLGRRYWNVEPVKNVESLQLAQFLAPRIPVLPH
LTAYRLSKKRLDDFLNLDFKSCLAIRGDMVHPGQDFQITQPIIELSHYKRGQNISICVAG
YPQGYTSLGGGPHEGRKDMLYLKKKVDAGADCIFTQLCYQPEPIVRFVKACREAGIQVPI
MVGLMVHDSMRSFEAIQDLSGVRMPEDMREELEELRETRGSCTDSEAVSQFFVNHAIKTI
CHLLDADIGCWGFQFYTMNSFPPVLAVLRELRNMGII
>A0A1C5JJB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora siamensis|TrEMBL
MALGLPSVLPNPQPAIGELIRAGQPTFSFEFFPPKTAQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVVGRLAGVGVRNVLAVR
GDPPGDPGGEWVAHPEGVRYAEDLVRLVRDAGDFSVGVAAFPYKHPRSADVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQLGTIERSVQLSGAPF
PTALAERFAKVADDPEAVRQLGVEQASEMCGRLLDEGVPGIHFITLNRSTATREVWQHLQ
AGARV
>A0A1H5ZRQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas daqingensis|TrEMBL
MSSSYPLGISFEFFPPNTEAGREKLIGVRDALAERGPRFFSVTYGAGGSTQGRTLSTVRS
VRESGITTAPHLSCIGSEKAQLRDLLAQYREEGIDSLVALRGDLPSGMGGIGELRYANEL
VEFIREETGDHFEIAVAAYPESHPQAPSFERDLENFARKVKAGANLAITQYFFTAEAYFH
FVERAQALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAFG
TEVVSRLCQRLLDGGAPGLHFYTLNQAEPCLRILDNLA
>A0A2K9QKI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya zeae|TrEMBL
MSFFHANHQEALNQNLAELQGRINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPLGGGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPIAPA
>A0A1F8T6V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_19FT_COMBO_62_14|TrEMBL
MNGYKAGSHLERVLRAGHFAVTAELGPPQAADGDVIRKKAALLKGYCDAANITDNQTAIV
RMSSIGAGAIALQEGLEPVIQMTCRDRNRLAMQSDLLGASALGMRNVLCLTGDHQSFGNH
PTAKNVHDLDSVQLVQMVVGMRDKKAFQCGEEIKGAEPRFFVGAAANPFGDPFEWRPYRL
GKKVEAGADFIQTQLIYNIERFAEFMENVRRLGLHQRVYLLAGIGPLKSPGMAKYMRDQV
PGMDMPNELVDRMTQAAEGIDKEDKKARAAAWRDEGVRIAIEQINQLRKIEGVAGVHIMA
IEWEEAVKLLVEGAGLYPRPEPASIPEADAGLTHE
>A0A094I482|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4519|TrEMBL
MAMSDDAAHEKGPVPSIGLHQIYNLGAAKLQLHRGVFNCKAGKPTFSFEFFPPKTAQGVQ
NLYDRMDRMHGLGPSFIDITWGAGGRHAQLTCEMVSVAQSVYGLETCMHLTCTDMGKEKV
DDALKNAYKGGCTNILALRGDPPREKEKWVATDEGFQYARDLVKYIRKTYGNHFDIGVAG
YPEGCDDQTDADLLLDHLKEKVDEGATFIVTQMFYDVPNFLDWVRKVRAKGITIPIIPGI
MPISTYASFLRRCNHMNAKIPPGWIEAMEPVKNDDAAVREIGRGLVTDMCRSILESGINH
LHFYTMNLAQATRGVLEQLEMLPSEERPLKQALPWRQSLGLGRRGEDVRPIFWRNRNKSY
VMRTQEWDEFPNGRWGDSRSPAFGELDAYGIGLKGSNEQNIKLWGEPKSVKDIANVFLRY
LNADIESLPWSEAPISNEADVIKNQLVELNERGLLTINSQPAVDGVKSSHPVYGWGPLNG
YVYQKAYLELLVAPELIDELLDRIARDPEVTYYAVTKSGTLRTNAPSDAPNAVTWGVFPG
KEIVQPTIVETISFLAWKDEAFRLGMDWAHCHDSSSPSRNVIQRVMETFYLVNIVHNDFH
QRDALFSLFEGLTVPNIDKAAEGTAAPAVAPAPAATAAPATNGDKVEEAPPAIVSNVLPV
A
>A0A2A9EP20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Georgenia soli|TrEMBL
MSTSSLIAPETALPTVSFELFPPRGTESDDAVWARIRRMAEAGPDFFTVTYGASGSARTS
SDAIVHRLLAETHVPVVAHLTCVGATRAELTARVRDLLDAGVRDFLALRGDPPAGQTRWV
PDPEGVAGSADLVRLIREVHSARSATGDVTVAVAAYPSGRNSGPGEIAALREKQAAGADY
AVTQVFYDAEDYATLVRDARAAGVTLPIVPGILPMTERRRLARLEELTGVPVPLSLDALL
DVRDDAVRLRRGLDATLALIDRVLAVGAPGLHLYTFNRDRPALDVLDHLRARGVLNPALV
SSGATPASAAPA
>A0A0S2VZU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Intestinimonas butyriciproducens|TrEMBL
MKLSELLSRGRPTVSCELFPPKVGTTLDQVEGVLRDTAALRPDFISVTYGAGGSTSKRTQ
EIAVRLQDTYHVPALAHLTCVSSTREEISSMVAALRAAGIENILALRGDIPRDADFPSPE
HYHYASELIGHIRSLEGGKELCIGAACYPEGHVECPHREDDIDFLKRKVDMGVDFLTTQM
FFDNDVLYRFLYRVLAKGITVPVIAGIMPVMSVKQIRRSCELSGTVMPPRLQGIADRFGD
DPAAMRQAGIAYATEQIVDLVAHGVEHIHIYTMNKPDVAARIMANLSDIIRPRG
>A0A2N6PE39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium luteolum|TrEMBL
MPPRSAAQQQRSGALLELLASYDPDYLAVTSAVGTGWSAGTAAFIEQLAATTRLRPLAHL
TCTAAPRSELIEWIEWFIDAGVRGFLAVRGDLAAGQSAPPRGHLAHADALVALLREVEQG
HVARLCGGRLAIGVAAYPSGHPESRHPAEDIDVLAAKQRNGADFAITQLFFDSALITAVA
ERARLAGVTLPIIPGIMPITGTARLQRMCRLSGLTPPPRISQTLAAARSPAEEYDIGLDL
TAGFVDELIAAGVPGLHFYTFNDPTTITELLSRLRPATLARLIVDRKDFP
>A0A1L2ZPC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neomicrococcus aestuarii|TrEMBL
MSGTVAEPEAATLVSNFSLEMTGKDVEALEAAAHLIPAGTRINVTFLGNEDLTLRVEAAA
AVRRLGFEPVPHISARRLHTESELTEFLEALREAAQPSTIFAVGGDPETPVGPYPDSLSL
IETGLFPQFGITEINIAGYPEGTPVIDEPTLWDHLRRKNAALKEQDLSGTILTQFSFDTE
PVLTWVAQVREHGVDLPIRVGVPGPAGIKRLLNYARRFGVASSAGIAKKYGLSLTNLLGT
AGPDRFINDLARELTPAHGEVKLHFYTFGGLSATAEWIRDFRP
>A0A1I8G2R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
MESQQNGHAYESDAPKILCRVSSGDSSSSASNATEMNDCHDSRPHSPVLPIAQYRPLISR
INRRIEKGKRWFSCEFFPPRTASGAVNLLSKFDRFAKGRPLFCDVTWHPAGNPMSDAPTS
SIMVASAMLNYSGIDTMLHVTCVGLPEERMTAALERAKGLGLKNILALRGDLPEAPEDGA
GGSGDVNNGDLLGDFKYAVDLVRFIRKRYGSFFNICVAGYPTGHPEASSYADDLLRLKEK
VDAGADFIITQLFFEADTFLKFQSDCRQLGIRCPIIPGVLPIQAYQSLRHIVKLSKLAVP
DEIIRTIEPIKENDEAIRNYGIFQCTQLCRKLLESGEVHGIHFYTLNREVATIEILRNIG
LWHEDLPRPLPWKHSANHERCGELVRPVFWSNRPTSYVHRTLHWEEFPNGRWGRPDAPAF
GELKDYYLFYLTVRATKKDRLNMWGEQLASERDVWRVFVNFVSGEPNANGFRVTRLPWSD
EELQQESRAIRDQLVALNSRGVLTINSQPNVNGLPSGDSTYGWGGPGGYVYQKAYLEFFL
PGQFLAALEQVLDRFSPRVNYQIVNREGTVNRLNFSQQEPIALTWGVFPASEIIQPTVCD
NGAFMAWKDEAFGLWTQEWANLYPEGSDSRRIIQGIAEDYLLVTLVDNEFPAENCLWSVV
EQVLTTQSQQGALV
>A0A1L7J1Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A1C6DVG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MKLSELLADNKTVLCDGAFATFYSKLTGNSERRCELENINNPEIVKRIHTQYINAGAKII
RTNTFSANTAILNISQDELIKVIKQGYMLARECAGENAVVCADISAIYTNDDHDKNPDAE
YRAIIDAFIECGADSFILETLPSIDIIAYPIEYIKSKKPDADIYLSFAIMPDGFTRSGVS
LNSLLDSIVKYKDKLCVVGLNCGCGPTQIQRHAVQFNDFIKSNTKLYTAVLPNSGYPYLE
RRRIAFSPNTEHFVDEIARLIPNNINILGGCCGTEPEHIKLLSEKLNGNISFEKIEIKET
KKSSPAPFSSRIANSDFVIAAELDPPYGTDLNKLINGANLLKEAGADIVTISDSPLGQVK
MEPVLCSARIHRECEIDALPHICCRDRNINALRSVLLGAHSEGIRAVLAVTGDHIAESDR
GVVKPVFNISSTQFMTIISEMNKEVFADSPILIGGAFNPDLKYAKSQLKRLEKKMECGAT
FFLTQPVYSAENIDVIEEARSLGAKMLVGIMPLVSYRNASFLNNEVPGINIPQDIIERFS
PNMTREESSAVGTEIAIELAKTYMTHADGFYFMTPFNRAEIVCDVINALPLKN
>F3L3H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aequoribacter fuscus|TrEMBL
MSTQQLSYEFFPPKTDAGREKLITQVLPQLADTNPKYVSVTYGAGGSTRDNTVGTVADIH
RSGMPVAPHLSFGTDSEDTMRALLQRYQAMGISRLVALRGDLPSGAGGSQQLVYASELVA
FIRAETAQHFTIEVAAYPEIHPEAKTYIADVQNLKRKFDAGANAAITQYFFSADAYFEFL
KTCSSMGIDKPIYPGIMPITNYDNLARFSRNCGADIPRWLDKKLAGFGEDLDAIKAFGQD
FILDLCKRLLDGGAPGLHFYTMNQAEPVISIVRELKRLGYFAD
>A0A4D4MKC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces avermitilis|TrEMBL
MDSVSTVPARAVAPLLEDFSLEMTGKDVPRLEEARATIPPGTRINVTFLGNEDLGMRLNA
ARAVKRFGFVPVPHISARRLRSRESLEEFLEALRAEGLADNVFVVGGDPATPEGPYDDSL
AVIRSGLLQKYGVRHVGMSGYPEGHPAITDPVLWSAIETKAAVLGEQRLPGGVITQFGFD
IDPVLTWVEAVRQRGIGLPVRIGVPGPAGVRRLMGYAARFGVGTSASIAKKYGLSLTNLM
GTAGPDRFIRALAERYDVQRHGEVKLHFYTFGGLKATSEWVAGFRTKDLTPVPLPRHAGS
>V4JJ07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp. PB-SRB1|TrEMBL
MKTQSNLEKVLSGGHLAVTSECGPPRGASAQTVVDKAKYLEGVVDAVNITDNQTAVVRMS
SLAGSVLVKQQGMNPLLQMVTRDRNRLAMQADILGAYALGIDTMLCLSGDHTKFGDHAMA
ANVHDIDSIQLIQMVKGMRDEGKFQGGAEIKGVVPKMYIGAAANPFADPFELRVMRLAKK
IAAGADFIQTQCIFNIEKFEKWMEGVRKMGLHEKCYILAGITPMKSVGAAKYMKNRVPGM
DVPQELVDRMSGVAKEDQPAEGIKICLETMERLKEVEGVAGFHIMAIDWEEKVEEIVKQA
GLYPRPQV
>I1GLP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachypodium distachyon|TrEMBL
MKVIEKIQEAAANGRTVFSFEYFPPRTEEGVENLFERMDRMVAHGPNFCDITWGAGGSTA
DVTLDIANRMQNMVCVETMMHLTCTNMPVEKIDSALDTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFSCALDLVQHIKAKYGDYFGITVAGYPEAHPEVILGEEGATEEAYSNDLAYLK
RKVDAGADLIVTQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGINTLHLYTLNMEKTALAILMNL
GLIEESKLSRTLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGSGKKLQEEWAVPLKSVQDINERFMNLCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINSKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYAEFFCAKDKLD
QLVEKSKAFPSLTYIAVNKEGETFSNVPANAVNAVTWGVFPGKEVIQPTVVDSASFMVWK
DEAFEIWSKGWACLFPEGDSSKELLEQVQKSYYLVSLVDNDYIHGDLFAAFKEI
>A0A5Z4JS29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEIASLIQEE
YQIPSIVHLPCIHSSKEKIIQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A536WST9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTPTNHALPLSLEFFPPKTPEGVIKLAAARRELYTVKPQFCSVTYGAGGSTQQGTMQTVR
DILAEGMPAAPHFSCIGASKASIRDQLAQFKAEGITRIVALRGDLPSGYGGTAGEFRYAS
DLIAFIRAETGSYFHIEVAAYPEMHPQARSPQTDLQAYVTKVKAGATSAITQLFFNTDAY
FRFVDEARAMGADVPIVPGIMPITNSSGIIRFADNCGAEIPRWVRLRLQGFGDDSESIKA
FGLDVVTALCDRLRSAGVPGMHFYTLNQATATLEICKRLGI
>A0A6B3KB60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas euvesicatoria|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGAAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCQRLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A5M3ZAL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus terreus|TrEMBL
MEKITDKIAALPPDSNYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRGLVDKALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRQQHGDYFCIGVAAYPEGHPADSFQDVQDPERDLPYL
VEKTQAGADFIMTQLTYDIDAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVKIPPQILSRLEEVRHDDDAVKRIGVDILKDLVDGMRDIPCPGLRGFHFYTLNLEKT
VSFILERCDLIPPYTEAGDDDALVDGGSLSALDSSSYVAPNGIPIRTLARRRSSINSLPH
NRVIVDREVSNESSKDSVSHEAPATSAGVPAMPPDRTTTLQISEGLGALGREATWDDFPN
GRWGDARSPAFGEIDGYGPSLHVTPSVAHRIWGYPVTRDDINTLFRRHVSGELHMVPWSE
GGAEEGSGGLNPETETIRPELLQLIDGKGWWTLASQPAVNGVRSDDPIFGWGPPREGFVF
QKPFVEFFCPTKDYQTALKPMLQKHGHEKLAWFATNANGDFESSLPAQTSDADPIEMNPN
NVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPRGSPTERFLEETKKD
VWLVCVVGQDFGAGTEMGSKEEEDEKKFMWRELVNC
>A0A2T4SE19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus nepalensis|TrEMBL
MSQLINKLKQNILVADGAMGTILYSDGLDTCPEAYNLTHPEKIERIHRSYIESGADIIQT
NTYGANFEKLKLFGLEHKVKDIHKAAVQIAKKAANNETFILGTVGGFRGVKQEPLSLEAI
QYHTEIQVDTLVEEGIDGLLFETYYDLEELTNIIKATKQKHNIPIVAQLTALNTNYLRDG
TEINTALQQVVNSGADIVGLNCHHGPHHMQQSFSHIELPEHAYLSCYPNASLLDIENSQF
KYSDNAEYFGKVAKQLINEGVRIIGGCCGTTPEHIQFIKSSIANLEPVTHKNVIPIKKYN
SCSRTQTKQQNLTTKVKQRPTIIVELDTPKHLDTELFFRNIKKLDDAHIDAVTLADNSLA
TVRISNVAAASIIKQQYTIEPLVHITCRDRNLIGLQSHLLGLSLLNVNEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNKGINTDGDALKTKTNFNIAGAFDPNVRKLEGSVKR
AEKKIESGTHYFITQPVYSTEKIKEIYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEAILEQFEAVKDDKEKTKALSLKLSKELIDTVHKYFNGLYLITPFQKVDYSLELASY
SQSITSSKQEAIL
>A0A085KAS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium yanoikuyae|TrEMBL
MTQTDRARHDAEGPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFVSVTY
GAGGSTRERTHNTVARIAKETPLAAAAHLTCVAASKAEIDEVADAYWEAGVRHIVALRGD
PPEAGTAFQPHPDGYKGAAELVEGLRKRHDFEISVAAYPETHPDALSAQSDIDNLKRKID
AGATRAITQFFFEADTFFRFRDTVAAAGIDADVIPGIMPVSNFAAVQRMSAMCNTDVPAW
MGRLFDGLDQHPAARQLVSATLAAELCRNLYMGGVRDFHFYTLNRAELSYAICHLLGLRP
QVAAELEKTA
>A0A7S7FNN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus rhamnosus (strain ATCC 53103 / LMG 18243 / GG)|TrEMBL
MKISQCFKDHQVISFEVFPPRKNATNIAMRPILNTLDAVKAADPDFVSVTFGASGNKPHM
GTLEVAKLIKNEFNLEPVAHLPAAQLTRAQVDAELRGFQEAGIDNILALRGDIPKSGRVS
EDFPYACNLIEHIHQVGDFDVVGACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYQFRERAALAGINVPIEAGIMPVINEHQIERMATMAGVHLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIATATQTIRNA
>A0A1C9J7R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Homo sapiens|TrEMBL
YPKGHPEAGSFEADLKHLKEKVSAGVDFIITQLFFEADTFFRFVKACTDMGITCPIVPGI
FPIQ
>A0A3B9R7I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter sp|TrEMBL
MKVTDHITNAKGKTLFSFEIVPPVKGRNIQELYNNIDPLMEFNPPFIDVTTSREETIYIK
KEGLLDKKTTRMRPGTVGICASIQHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIQNV
MALRGDARSEQKYFEPTEGGHPFAIDLVKQIQDLNKGKYLHETVESEHSSEFCIGVAGYP
EKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEAAKEIGITVPIIPGIKP
IAVKRHMQLLPQVFRIDMPQDLIEAVDACATNKDVRKVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAEALF
>B4V3E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Mg1|TrEMBL
MALGTASTWSDRAHTVRDLLASGSSYSFEFWAPKTEKGERNLWEALRRVEAVAPSFVSVT
YGAGGSTRGGTVRATEQIAADTTLTPVAHLTAVDHSVAELRHVIGQFADAGIRNMLALRG
DPPGDPMAPWVKHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRYFVDK
CRAGADYAITQMFFHPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
DAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A1C5VAN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Blautia sp|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPGTIEHLMKYRPEYISCTYGAGGGNVGANRE
VCQMIRNAGTVPVTHFTVIKNTKEGIRQQLEQYLADGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A1G7CS34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulophaga baltica|TrEMBL
MKVTDHIKNANGNTLFSFEIVPPVKGNSIQELYDNIEPLMEFNPPFIDVTTSREEYVYVD
KAGLYDKKITRMRPGTVGICASIKHKFDVDTIPHVICGGFTKAETEYMLIDCHYLGIDNV
MALRGDAMKEEKYFKPTEDGNCFASELVTQIQNLNQGRYLHDDVQGEDKSDFCIGVAGYP
EKHLEAPSFKSDLIRLKQKVDAGADYVVTQMFFDNQKYFQFVEAAREIGINVPIIPGIKP
IAVKRHLQLLPQIFSLDLPHDLVEAVEACKNNAAVRQVGVEWAIQQSKELKAAGIPVLHY
YSMGKSNNIKAIAKEVF
>A0A418Z534|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Mbandaka|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5I0KY86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Napoli|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0D7UXV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas meridiana|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAARNPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRDETGDHFDIAVAAYPESHPQAPSLDKDVENFARKMNAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GTDVVTRLCERLLDGGAPGLHFYTLNQAAPVLKVVDNLS
>A0A8C8FW82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
MVSFGRVEAIFIISPGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTESGDHWFS
LEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCG
LESILHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKH
IRCEFDDYFDICVAGYPTGHPEADSYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVR
DCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIRNYGIEQ
TVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVED
VRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMW
GEELTSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMMDELDKVNRRGVLT
INSQPTINGKPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPRVNYHIV
NVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAELYDD
ESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPTEQPVEQPAE
ESPVEDQSPK
>A0A8E6Y3C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella pullorum|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2R4EQ69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax avenae subsp. avenae|TrEMBL
MSLSTHKAALPVSFEFFPPKTPEGADKLRAVRQQLYVRRPEFCSVTYGAGGSTQEGTFGT
VREILSEGVQAASHFSCIGATREGVREQLAQLKAMGVSRLVALRGDLPSGYGAGGEFHYA
SDLVAFIRAEAGDDFHIEVAAYPEVHPQARSPEADLQAFATKVRAGAHSAITQYFFNADA
YWRFVDDVRALGLDVPVVPGIMPIMGSTQLMRFSDACGAEIPRWIRLRLQGFGDDSASIR
AFGLDVVTALCERLRAGGVPSLHFYTMNQSAATLEICRRLGL
>A0A341BS40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neophocaena asiaeorientalis asiaeorientalis|TrEMBL
MVNEPRGHGGPSPRWESSSSGSESSKDSSRCSTPVLDPERHERLREKMKRRVESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKRLGLKNILALRGDPTGDQWEEEDGGFNYAVDLVKH
IRSEFGDYFDVCVAGYPKGHPDAESFEAGLKHLKEKVAAGADFVITQLFFEADTFFRFVR
ACSEIGITCPILPGIFPIQGYRSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
ALSLCRELLASGSVPGLHFYTLNREVATTEVLKRLGMWIEDPRRPLPWAISAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPVVGWGPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGDNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRTIIQHIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLSGPPQSKRETEAP
>A0A2D9K6F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantimonas sp|TrEMBL
MSQTPPLAGSGLRVSFEFFPPKTEKMEENLWRSIERLAPLGPSFVSVTYGAGGSTRERTH
QTIERILKETTLTPAAHLTCVDASREEVDEVVRQYWETGVRHFVALRGDGQNGVGGKYVP
REDGYRNAVELVAGLKAFADFEISVAAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNDVFERYVERVRRAGIYIPIVPGIVPIHDFVKVARFSNATGAKIPSWLAERFDGLEE
DPQTRSHVAAAVCAEQVLDLQKRGLSDFHFYTMNRADLVYSICHILGMRAGTAAAPKSEA
AAA
>A0A2J8E609|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium dahliae|TrEMBL
MHIKEMLADAERDGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIA
ELTCEMVTQAQSVYGLETCMHLTCTDMGLDKVNDALRKAYKAGCTNILALRGDPPREKEK
WVAADGGFEYARDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGATF
IVTQMFYDADNFVRWVGKVRERGITIPIVPGIMPIATYASFMRRAKHMNCSVPQEFMDAL
EPVKNDDNAVREVGKVLVAGMCRKILAAGIHHLHFYTMNLAQATRMVLEELNWMPTSERP
LKQALPWKQSLGLGRREEDVRPIFWKGRNKSYILRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNIKKWGEPQTVQDIATLFVRYLRNEIDCLPWSESPLTNEADPIREDLIA
LNKRGIITINSQPAVNGVKSSHAVHGWGPKNGYVYQKSYLEMLVHPDLYPEIISRIEKHP
DMTYYAVTKSGNLKYNAPSDGPNAVTWGVFPGKEIVQPTIVEGISFVAWKDEAFRLGLDW
AHCFEQSSPSRVLVERIMNEWYLVNVVNNDFHQQREIFDLFEGLSVKEYDDIKPVAKDVA
PDAVSAPTNGTTNGIAVPAA
>A0A815PFT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood1|TrEMBL
MTLTHTEKSTASNHCDVHQNGIDNRKMSNSSDYFGEFKHSQSEHTLLNTRANSLPPVKYI
SLTEKIQKRIANNDRWYSLEFFPPRTTNGAVNLIGCLERMAVSEPLFCDITWHTAGDPAG
TKETSTMMIANTMLNYCNIDTMLHITCYGAKKATMIEYLSKAKDFGIRNLLALRGDPPVG
EKWDPEKTDFRYASDLVKFIRENFGDYFVICVAGYPKGHPDSKTYEEDLHYLKEKINCGA
DFIITQLFFQAETFLKFQSDCQAVGITCPIIPGIFPIQAYASFKNIVRLTKLDVPDEITA
HMESIKDNDEAIRDFGVQTCVDLCKGLLDSGKVHGLHFYTLNREHATSEILKQLGFGFED
PPLRALPWKKTSKNHVRSKEDVRPIFWSTRPKSYIHRTSDWNEFPNGRWGISSAPSFGLL
TDYHLFYMKIDATRDELLDEWGHELTCEQDVWKMFVCYIGGKKNSSDKILRHFPWKDEEI
SPETNLIHNELVEYNRKGILTINSQPVVNGKPSTDPIFGWGERNGYVYQKAYLEFFTSAN
NIPALRAVLKNFPGVNYHFVNKSGEVNETNADDEQPIALTWGVFPGREIIQPTVVDPVSF
MIWKDEAFGLWMERWGKLYEPDSRSYSIIEQISNTYFLVNLVDNDYPQGSCLWAVLDAMF
EYQQKTNQDINR
>A0A640JG07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax boronicumulans|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPQFCSVTYGAGGSTHQGTFGAVQEILAE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFATKMKAGADSAITQYFFSPEAYFRFVDD
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLQAGGAPAIHFYTMNQSAATLAILERLD
>A0A349VMN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MVVTQQVSYAKESFDLSFELFPPKTAESEAMLWQTVDELMGFDPTLITCTYGAGGSTQTK
TLEVLDGVLVRYPTVAVASHLTCVGRTTDQLREYLREAQQRGVTSIVALRGDPPQGETTF
TPIANGLHYAVELVALIKQEFPELRILVAGYPETHQEAVSPEVDLEHLKEKCNAGGDTVV
TQLFYDNTDFFRFRDRCSSIGITKPIIPGLMPVTNFKQIKRIATLCKARLPNSFTHALEK
AGDDADAQFEAGVDYASKQAEELLSNGIPGMHLYVLNKSPAAIRVLEQVGMTRP
>A0A412ZBC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster bolteae|TrEMBL
MKIRDILAEGKPTLSFEVFPPKTEDAYDSVEKAAAEIAKLKPSFMSVTYGAGGGTSEYTV
GIASAIKEEYGVTPLAHLTCVSSTREKVHHVLGELRERGIENVLALRGDIPQDGSTPKEY
HYASELIREIKKAGDFCIGAACYPEGHVESANKSVDIDYLKQKVEAGCDFVTTQMFFDNS
ILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTYLPSRFMSIVDRFGDNPAAM
KQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A7C4HVJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MVQAFSNLMRNILDGRFVYTGELEPHKSIDLSEVISWAKTLKETGRVVAANVTDNPKSVG
AISSLVASYIIQRETGLETIYQLRCSDRNRLALISDLLGAAALGIRNVLALTGDYVRQGD
TPTAMPVYDLDGTQLVDLIHRMVYEGKDIDGNEIHGPRPQFNIGAAANPNFKPLEVEVLK
IERKAEVGAEFFQTQVVFDANVALDFLDAVKHINAAFLIGIFPPRSYAQAEYFAKYVPGV
QVPAEFLENLKKISEIPDKKERRKKIDEYNIEYFSDFIKAVKKKPSCKGIHIMAVGYPEV
VGPLIERAEGL
>A0A2S7DTH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas cucurbitae|TrEMBL
MHQDTIGPAGTRIDAYSLEVGANDIAALSAVALRIIPGSLIAIPSLPGQDDAMRLAAARN
VRALGFAPMPHLVARRVTSLDDLQAFLSRAVDTAGVEHCLVIAGDRSSPIGPFPDSASLI
ATGVFERAGIKSIGVAGHPEGHPAMHAGAQWDVLDRKCRSIAERGMAPLIVTQFAFDADL
VLRWLEALRARGIDTPVRVGVPGPAGVAVLARYAARCGVSTSAAMLSSYGISIGKLLGTA
GPDRFVDRLAAGLMHAHGDVRLHVFPFGGVARSVAWVEHYRSRSSTWTPTALR
>A0A0P0M3N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKDGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVEAGADYVVTQMFYDNRKYVDFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAMKCKDDKEARALGIEWCINQCRELIAYGVPGIHF
YTVGAVDNVKEVATAVY
>A0A1V3KUF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter ratti|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMENMLWESIHRLKVLKPTFVSVTYGA
NSGERDRTHSIVKTIKQETGLEAAPHLTGIDATPEELKQIAQDYWDSGIRRIVALRGDEP
KGYDKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHIIT
QFFFDIDSYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPSWLAKAYDGL
DNDPTTRNLVAASVAMDMVKILSSEGVSDFHFYTLNRSELTYAICHMLGVRPSV
>A0A350B907|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium|TrEMBL
MKIIDILNQDKITLSFEVFPPKLTKNYDDVAFKAKEIAKLHPDFMSVTYGAGGGTSEYTL
NIAKEIKEKENVEVMAHLTCVSSSKEHVHNMIHRLKENHIENIMALRGDIPSGGSKFHDY
QHASELIKEIKASGDFCIGAACYPEGHPEAGNKDTDIKNLKKKVDAGADFLTTQMFFDNN
VFYNFLFRAREAGIDVPIVAGIMPITRGLQVKRARELSNCSMPQRFISMVDKFGDNDEAM
KQAGIIYASEQIIDLIASGIKHIHVYSMNKPDVACAIMHNVSEIIR
>A0A0A6TDY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. phaseoli|TrEMBL
MISTDTPHLASTVTDAYSLEVSVKDIGALTNAAPRIVPGCAMFIPYLPGQNEAARLAAAR
TVRGLGFEPVPHLSARRIGSPEELQASVARLVDEAGVTRCLVIAGDPATAKGPFPDSVSL
IETGVFERAGIRSVGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
LVVTWLEALRARGMSHPVRVGVPGPASVAVLARYAARCGVGACASVLSNHGISIGKLFGN
AGPDRFVDRLVSRLTQAHGDVRLHLFPFGGIAQSVEWVAQYRSRNASQRLVGSEPADQA
>A0A0F2CGU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gordonii|TrEMBL
MVRHHSPSLSFEVFPPNPAVGNEKIIQALREMQDIAPHYISVTASNNKFNIEETTVRLAD
FIYNDLKIPTIAHLPAVYLTKEMVLDTLQALDKVGVHKILALRGDIFPDVAPKDDFKYAT
DLIEYIKEEAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDIPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGVHLYTMNNAATAHHIYQATHTFFS
>A0A4V5UVF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella jiaozuonensis|TrEMBL
MRGFELICEVEPPTRPDLKRVRHQIGVMSPIADGFLIPDNHIGRATVSSVAVANEVQLMG
ARGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDDPAEGARTSQLTVRRMIEQARE
TSYPGCNPFQVGAATRLAKVPSWKAEADFLYVQVSYDLDELLRWRESVELDIPVYAGVMV
LASAKMAHNLAALPQLTIPDELIEAVERDRDAGVDHACEQILKIRDSGAFDGVHLIPVSR
YRQVAARLEREL
>A0A2E6B5F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSQPQISYEFFPPQTEAGRTRLIETAEALAVTDPAYFSVTYGAGGSTRTRTYETVVKLME
NGMTTAPHLSWGDDSESTLVSLIEKYRELGVTHMVALRGDPPSGIGATARIRRAHSLVNL
IRRHFGNTFNLYVAAYPETHPDAISPEDDIRFLRKKIESGADGCITQYFFNADSYFYFID
RCRSHRIETPIVPGIMPITNYEGLVKFSDGCGADIPRWIRTRLAHLADNPEDLLAFGIEV
VTNLCERLLNGGAPGIHFYTLNKPHASVQIARNLGLG
>A0A1V8QI44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KGYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLSTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A817QQ44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MEFTLGDNQTVPGDCKMHAHETHLESIHNLNRLKRIESEGANIAGKICSLQSAKYVSLTE
KISKRIADNDRWFSLEFFPPRTPSGAANLIGCFDRMAAGRPLFCDITWHPAGDPAGDKET
SSMMIANTMLNYCGIDTMLHITCYGAKKAAMLEYLYKAKDCGIRSLLALRGDPHVGEEWN
PAKSDFRYALDLVKFIRQHFGDYFVICVAGYPQGHPDSTSYEDDLDYLKEKIDCGADFII
TQLFFQAETFIKFESDCRSIGIKCPIIPGILPIQGYASLRNIVRLAKLDIPKEILACIEP
IKDNDEAIRNFGVQACLDLCCALLDSGKVNGLHFYTLNREFATIEILKRLGLWLDEQSLR
ALPWKKTSFSHARSQENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGISSAPSFGVLTDYH
LFYMKIDATRDELLDEWGRELTCEQDVWKMFACYIGGEKNSIDKVVRRFPWTDEELSAET
TLIQKNLVEFNKRGILTINSQPAVNGKSSSDPVVGWGTPNGYVYQKAYLEFFTSAENIPA
LRSVLKTFPGVNYHFVNKSGEANETNTDDEQPIAVTWGVFAGKEIVQPTVVDPVSFMIWK
DEAFSLWTERWGKLYEPESRSHAIIEKIANTYFLVNLVDNDYPQGSCLWTILDSMFEYQK
LPKKNVES
>A0A5D2P7S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium tomentosum|TrEMBL
MKVIDKIQSLSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
NIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DVLVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A6V7BLM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. pelargonii|TrEMBL
MIYPDTPSLASTITDAYSLEVGATDMPALAAAAPRILRGSTIAIPYLPSQNDDARLAAAQ
TVRTLGFAPMPHLSARRIASLDALHAFVGRAVDEAGVERCLVIAGDAPSAIGPFSDSVSL
IDTGVFERSGITTIGVAGHPEGHPGMPATDQWDVLERKCRSIAERGMAPLIVTQFAFDAD
IVLTWLEALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACASMLSKYGISIGKLFGS
AGPDRFVDRLATGLTDAHGDVSLHFFPFGGIAQSVAWVEQYRSRSAAHILSTSASRRSQ
>A0A6L6BBJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSKLRDVITQTKDVVYTAEFPIIDGGGMEQVKKNVERLAPWFVAVNATDNTAAHAHASNV
SVAIAMKQHGLEPIMQIVCRDKNRLAIQADMAGANLHGIENIALLTGDDVTAGDEPETRR
VFDLDGPQAINVASILNAGTYLSGRKLNPAPNFFICSVENPFAPPHDYRIERVLKKHRAG
AQMIQLQIGYYPERLEKFCAGVAATVPDLAIIPSVVLIKSAKPLSFMNDKVPGISVPQDV
IDRVAQSTDQAEAAYHLALEQCQHALALPGVRGLHITDFRHDDTLERLMRDLGRTPNQYT
>A0A6I2XJA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSAPTISFEFFPPKDVPGEERLWRAIEALGPIAPDYVSVTYGAGGSTRDRTIAITSEITH
RTHIPTIAHLTCVGSTQEEILHILTRYRDVGIKSILALRGDPEGGPRAPWVSIPGGLNHA
DELVALASEFGDFTVGVAAFPDGHPASAGNLDKDIDVLIRKEDLGASFATTQFFFDATKW
SSLVARLEERGSSLPVIPGILPVTNVKQLVRMSELSGTPIPDAMRKRFEAIESDADAVRE
LGVEIATELCQKLLAAGAPGLHFYTMNTSTATSQIYKNLALKR
>A0A6I3GP37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSQMREKLENTNEVVFTAEFPSLDGGGMAKVEKNAARLAPWFVGVNATDNPAAHAHASNT
ASAIAMKMHGIEPIMQIVCRDKNRLAIQADMMGAALHGIENISLLTGDDVTAGDEPESRR
VFDIDSTQAINIARIITTGKYLSGRKIDPAPDFYISAVENPSAPPFDYRIERALKKYRAG
AKYLQLQICYHPDRLEKFCAGVAKIAPDLKLIPTIVLVKSAKPMSFMHDKVPGIDIPQDS
LNRVTAAADQAEEAYQLTLELAKHALTLPSVRGLHVTDFRHDDSLDRFMYDLGQKPRN
>A0A4Q7HTC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella derby|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A850QX94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium damselae subsp. damselae|TrEMBL
MQPITNYQALSLQDSELRVRYNDVTRGVYFIGTTPPKTSTDLSDVDGIADKLVDRIKDLA
FDGLIVYDIQDEGSRISKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSEPEVFN
QWLNEAWEQYQVRDIVLVGSPSTQNQVSLPLHEAYKTIADNEHPFFTGGIMIAERHAKKG
NEHQRLIEKYQQGCNFFISQAIYDTQATIDLLTRYAIECQEKGLKPQRIILTFSPCGSAK
TLEFIEWLGVSVPEATSLRILNADNPLHESIKMCCNSLNQILEAVVEYDLPLGLNIESLT
NRKEEIEGSILLYKLLRSTMDMYLAQHEFRKQQGLKKAF
>A0A156IZZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter roggenkampii|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A523NRM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospina sp|TrEMBL
MKIKAILEKVCPSFSFEFFPPKDDEGFDKLFTTITQLKPCQPTYVSVTFGAGGSTRTKTI
DLVGRIKSEIGLESMAHLTCVGSDREYIAAILDTLQAQGIQNILALRGDPPQGQEEFEKP
ENGFAYANELVAFIRANYDFCIGVAGHPEGHMECPDKKADLDHLKRKVDAGADFIVTQLF
FDNRFYFDFIGRAQNLGIQVPIIPGIMPILNVKQIQRFTKMCGSTIPASLMERLEAVQDD
PETVRQLGIDHATEQCEDLLQEGAPGIHFYTLNRSNATLKILESLKKLTDQTGD
>A0A348NDX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKITQHIAAAKGKTLFSFEIVPPVKGGNIQELYNNIDPLMAFNPPFIDVTTSREEFVYLK
KEGLLEKKLTRMRPGTVGICASIKHKYGVDTVPHVLCGGFTKEETEYLLVDCQYLGIENV
MALRGDAMAGQRYFEPTPGGHTYAKELVGQIKDLGTGKYLHEEIESAHSSSFCIGVAGYP
EKHMEAPSLQQDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVAAAKEMGIDVPIIPGIKP
IAVEKHLQLLPQVFSLDLPQDLIDAVSDAKDKAAVRQVGIEWAIAQSKELLAAGVPVLHY
YSMGKSSNIEAIAAEVF
>A0A2E0ZPZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSGASDSTPPRKGPIRSQAEKATHRRLLEDMTYELIPLKNVHDQAAFLPENSTISVTCSP
AKTIDDTLDLCATFADDGHTTIPHFAARMVEDEAHVDSIVQRVNEQGIRKVFVVGGDAEP
RGPFTDAAGFLRSFLDRRPDIDVVGIGSYPDGHSTIPEQALLDAQMEKQEMIVEAGLEGY
MATQMCFDAETIRDWLRQRRSAGLTLPCHLGVPGAVDRTKLLTISLRLGIGHSARYLKKN
RASVIRLLSPGGYNPNKLVAPLSAVADELDIVGIHCFTFNAVDTTEDWRQKSLRKLAPNG
KR
>A0A0E2GL97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter radioresistens DSM 6976 = NBRC 102413 = CIP 103788|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKLVHQDLQHLNPEFFSVTYGAGGSTRERTLAAIEEFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQNIKRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIRRFIEKVNAGANAGITQFFFNPDSYFYFL
DRLAKEGIHIPIAPGIMPIINASNLIRFADGTGAEIPRWIRKQLSAYGDDSVAIKDFGHE
VVLKLCERLIAGGAPSLHFYSMNQTEPTRQLVLDLGLA
>M7ZYT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Triticum urartu|TrEMBL
MAASKGRTVLYFEYFPPKTEEGVENLFERMDRMVAHGPNFCDITWGAGGSTADVTLDIAN
RMQNMVCVETMMHLTCTNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDKFVQVAGGF
SCALDLVEHIKAKYGDYFGITVAGYPEAHPEVILGEEGATEEAYSKDLAYLKRKVDAGAD
VIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTKIPAEITAA
LDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNLGLIEESKL
SRTLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWGDSRNPSYGALNDH
QFTRPRGRGKKLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPETTIIDNQL
VKINSKGFLTINSQPAVNAEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKA
FPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWS
RGWACLFPEGDSSRELLEQIQKSYYLVSLVDNDYISGDLFAAFKEI
>A0A3R9T247|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKARINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A6A2RN91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides xylanisolvens|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVTQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A8C5YEU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcebus murinus|TrEMBL
MVNEARGSGGLNPRSEGSSSGSENSKDSSRCSTPGLDPERHEKLREKMRRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSQDDITGHLHKAKQLGLKNILALRGDPTGDHWKQEEGGFNYAVDLVKH
IRNEFGDYFDICVAGYPKGHPEAESFEADLKYLKEKVSAGADFIITQLFFETDTFLHFVK
ACANMGVTCPILPGIFPIQGYHSLRQLVKLSKLEVPQKIKDIIEPIKDNDAAIRNYGIEL
AVNLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELSSEESVFDVFVRYLSGEPNQNGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYDE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDALELLNRPTQSEREAEAP
>A0A222HH87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium meliloti|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHERCYILVGVG
PMASAKTARWIRSNVPGIHIPDSIIKRLEGAQDQKKEGKQLCIDIMNEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLRGRKPWTREAAPTDALVAERLEHIREGKEENQQQMAEAAAH
HPH
>A0A315GSF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar 4,[5],12:i:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAKADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A011TDY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquamicrobium defluvii|TrEMBL
MNAAQHRHPDENPAGAHLPLEPLPGHFSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRVMRDNGKFLSGRKLTTPPQ
VFLGAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRDFMQRARDLGLTDKVF
ILCGVGPLASARTAKWIRSNVPGIHIPDAVIRRLEGAQDQKAEGKRLCIDIIDEVKEISG
VSGVHVMAYRQEEYVAEIVDESGVLRGRRPWKREARADDALVAERLEHILGEDVTEKQVD
MVRSAH
>A0A1B9PSY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio lentus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A7D5JF08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. LPB0260|TrEMBL
MSQEHSFSFEFFPAKTEAGHEKLLNTARELAAYKPDFFSCTYGAGGSTRDRTVSTVLQLN
DEVRVATAPHLSCVGDSKAELRQLLNLYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VSFIREETGEHFHIEIAAYPEMHPQARNFEADIANFVRKAKAGASSAITQYFFNVDSYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSDSIRAYG
EQVVSEMCERLLQGGAPGLHFYTMNLAGPSLAIWNNLKLSR
>Q10BJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryza sativa subsp. japonica|TrEMBL
MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLK
QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNL
GLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLD
QLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWK
DEAFEIWSKGWACLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAFKEI
>A0A3R7JE73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora kernoviae|TrEMBL
MKVIDKINASIERQEVFYSFEFFPPKTPAGVENLYARMDRMAALEPLFCDMTWGAGGSSA
QLTTELSANAQKLSGLEMLMHMTCTNMAAGDIKKALDQAKEAGIQNILALRGDPVRGATS
FDECDKGFSHAVDLVRYMREEYGDHFCIGVAGYPEGHTESEDKAADIKYLKEKVDAGADF
IITQLFYDVKVFVEFVKECRAVGITCPIIPGIMPIQNYGGFERMTSFCNTYVPEEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSSRAAESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELAESH
FAATNTSTPKERRGMWGDAPATKHDVRQTFVQYVRGEISSLPWCDAALHAETSTVQHELA
SANAAGFLTINSQPRVNGALSDDPLFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
SSVQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYENGSQSAKLLREIHDTYFLVSIVDNDFGPDKGTYVMTCGQDKTVKLWNPHRSGVE
NDNEALLIKSYEGRHGYDVQDVAITHDNAKFASCGRDRDVFMWDVPTAKVIRKFEGHKQS
VNCVRYNADSSVLLSGSYDKTIRAWDIRARNAYTPIQVLDDFKDSVTSMVVTDHEIIAGC
VDGVVRTFDLRAGQISREHIDEPVVSVAHSPDARFVLAGCLDGSIRVIEKANGTEVKSYR
GHIVQDYKLDCGFSNDGAFVLSGSEDGKIYWWDLLDATNAHSISAHNKPVRALACHPESS
MFVTGCIDGSAKIWSHN
>A0A0B5DIP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces nodosus|TrEMBL
MALGTASTRTDRARTVRDILASGRTTYSFEFSAPKTPKGERNLWGALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVEDTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGSWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPERHPRSPDWDSDVAHFVD
KCRAGADYAITQMFFRPESYLRLRDRVAAAGCTTPVIPEIMPVTSVRLLERLPQLSNAAI
PADLKERILGAKDDPAAVRSVGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSQRT
>A0A4T0LNQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia mellicola|TrEMBL
MKITEKLLAAEREDRLWWSFEFFPPRTAQGMTNLVDRIERMRRLGPEFVDITWHSGGRTA
ELTTELVKTCQASIGVETCMHLTCTGMPREKVINALEEAKKNGCTNVLALRGDPPRGQTE
WYPHPNGFTYAADLVRHIRQEYGDYFEVAVAGFPEGNLQYKHSSDKDNEIQYLKEKVDAG
ADLIMTQMFYDVDNFIDWCNKVREAGVTVPIVPGIMPIQTWNGFQKAVQMAQTKVPQDWM
DQLEAVKEDDAKVREVGTKLVSDMCRKILDANVGIRGLHLYTMNLERGPKMILQELNLIP
QTQILNPLPWRPSLTPTRRAENIRPIFWANRQKSYLSRTEMWDEFPNGRWGDSRSPAYGE
IDGWGPTINFKLDEAREIWGEPLKYDDVCNLFSRFCLNDLKALPWSDQPPARETSVIDRQ
LAMMNKIGFFTINSQPAVNGARSDDPVHGWGPKGGYVYQKAYLEFFVSPDNLDKLISRIE
LNPMMTYYAVNRRGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELG
YQWSDIYEKGSTSQQLIKDIMDSHFLVNVVHNDFKNGQDIFKPFLDEIANESAIKDTTKN
>F8TEQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium autoethanogenum|TrEMBL
MSLLKEAFEKGEFAITAEMAPPKGTDLSHLIECAKKIKGRVQGVNVTDFQSATLKATSLA
TCKVLKDAGLEPVFQITGRDRNRIAIQGELLSAGVFGIENVLALTGDYTATGDHPGAKPV
YDLDSVGILQVASILNGGKDMGGTDLKGKPDFFLGACVTPRYDPLELQVIKMKKKIKAGA
KFFQTQAVYDMETLKKFKEETKAQGVDAKVMVGIIPLKSAGMAKYMNKNVPGIFVPDELI
DRMKNAEDKVQEGIKIAGEFIKAVKESGLCDGVHIMAIGAEENVPLILDEAGL
>A0A2E8GQ35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNRHRKHQPLLPYRLRHEVAMRLIDLYRRQPFVFSIEVFPAKTEEGMEALKQTLGTFAKF
RPDYFSVTYGAGGSTRENTHTLATHLQNTLSIETMAHLTCVSHTCKEIEVVLYRLEKSGI
ENVMALRGDPPQGSTEFQTPENGYSHASELVAAIRERGGFGIGAAGYPEGHTENPSKSDD
RRRLVEKINAGADFVATQFFLDNTFFLHWRDRLATEGVSVPLVPGLLVPTSLKQITRMAD
FCGIRISNKLRTQLETHHTDPEAMKQIGLEHATHQLEALLREGIPGLHLYALNKLEAVQY
LAPLLPHSSKDIPTPCTA
>A0A1C2NHZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGEHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A4IIX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenopus tropicalis|TrEMBL
MVNANSSDSGTASCSSAEDSKESSRCSTPVLDVERHERLKDKMRRRVEAGDRWFSLEFFP
PRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASAAVNFCGLETIL
HMTCCNQTKEDITKHLHKAKHLGLKNIMALRGDPTGEEWEEEAEGFNYAVDLVTHIRHEF
DDYFDICVAGYPRGHPEAEGYDQDLKHLKEKVDAGADFIITQLFFRAETFLTFINDCRAI
GITCPILPGIFPIQGYGSLRQLVKLSKLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMC
RELLDSGLVHGLHFYTLNREVATIDVLKRLGMWKEDPRRPLPWAVSAHPKRRVEDVRPIF
WASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGQELS
SEESVFEVFTYYISGEPNPNGHKVTCLPWNDDPLAPETNLLKSELQKVNKRGILTINSQP
NVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVNVHGQ
NITNAADLQPSAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEEESPSR
MIIQYIHDNYYLVNLVDNDFPLENCLWQVIEDTFKEHDSPTDQ
>A0A3Y3V2U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPSL
>A0A235VAQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae subsp. pneumoniae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A0J6H9R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas lini|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARHLATFNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A0Q1U298|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A1I5H6A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus pantotrophus|TrEMBL
MTTPAISFEFFPPRNLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETLQIVQDYAAAGVHEIVALRGDAPQGQDRFTPHPEGFANSV
ELIEAIAARGDMTIRCGAYPEPHPESPDTAADVAWLKRKVDAGATSAMTQFFFDAETYFR
FRDACQAAGIAAPIIPGILPIQSWAGTRRFAERCGTSVPQWAEDAFAAAGKEGEAQLALE
TCVKLCERLVEGGVDRLHFYTLNKPDLVLKVCAALGIEPKGEFSRVA
>A0A6G2KME1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MTRIADLLGAQNTLSFEFFPPADEVAAKQLEKTLDELAGLSPSFVSVTCGVGGDGHDRTR
DIVTDICRDRTFPAMAHLTCVGHTREGVAALLDDYAAAGVANILALAGDPPDGSAISGDF
HYASELVEVIRDHPADFSVGVAAHPEVHPRSTNRASDRQHLAAKLSRADFAITQFFFDPA
DYVQLCEELADLGCQQPVIPGVMPVIWPKSIRRFADMNGSTVPEDLFTRLESMPAPDRIG
AAAESAAKLSQTLLDAGAPGIHLYTLNRPEASTQITELLNL
>A0A1S2BP98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAARLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
AKLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQG
>A0A256V8Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limosilactobacillus reuteri|TrEMBL
MTSLSYEVFPPNSAVGINHLNQVLAALQDLEPSFISVTCSSKTARLAQETVRVADYVENC
CHVPAMAHLPAWYLSRTDVDRIMAQLRERHVGRVLVLRGDERPGLAKKDDFPHASDLVAY
IRQNYPDFQITGACYPEKHPESLDMVAELQHLKLKVNAGCDQIITQLFLDNQSYYRFREL
CAIAEIDVPIIAGIMPIINERQANRILRTSAVTVPEKFKDILAKYHDHPEALKQAGISYA
IDQIVDLVTNDVAGIHLYTMNQADTARQVEQNIGALLQVSC
>A0A166KM68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFETDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A738E147|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella abortus-equi|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0D6XSN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus microti|TrEMBL
MSRLLNTLKHKVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVEHIHRSYIEAGADIIQT
NTYGANFEKLKQFGLEHKVKAIHEAAVAIAKRAANDETFILGTVGGFRGVKQGDLSLPAI
LYHTEIQVDTLVTAGVDGLLFETYYDLEELLKVIKATRERFPDIPIIAQLTASNTNYLID
GTEINDALQQVNEAGANIVGLNCHHGPMHMKNSFSHIALPDNAYLSCYPNASLLDIDNDT
FKYSNNAQYFGDTAEQLIQEGVRLIGGCCGTTPEHIRHIKTSVASLKPITEKKVIPIHKQ
REKKKKTTQRLTLSERVRQRPTIIVELDTPKHLDTTRFFDNVKALDDAKIDAVTLADNSL
ATVRVSNIAAASLIKQRFSIEPLVHVTCRDRNLIGLQSHLLGLSLLGIHEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNKGINSNGDALKTETHFNIAGGFDPHVRNIKAAVR
KMETKIESGMDYFITQPVFTKEKITEIYEATKHLDVPIFIGIMPITSYKNALFLHNEVPG
IKMSEDVLAQFEAVADDKAATYELSLSLCKSLIDHVHRYFNGLYLITPFERVDYSLELAA
YSKSITDHNQEVIL
>A0A183H7U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Onchocerca flexuosa|TrEMBL
MDTIMDPVTVDNEAGTSRTKNDDGCVIDSSEITNQAAISSYPVSNQWSESRTDWVTHGTY
VPLRDRIKKRIAEGIPFFSLEFFPPKTRNSVANFFARLDRFREGNPLFVDIAWHFGSDPG
NINSETSSTSVAAGCLDYCGIDTVLHITCCSYTKEQSIRHLEQSKALGLKNILALRGDLP
RQDENPILYKYRALDLIRWIKEEYKDYFTIACSGYPAGHPEAPSYRADLLYLKAKVDAGA
DFIISQIIFDGQVFEKFLRDCREIGITVPIIPGILPIQSYESIRRIAELSQLIIPDSILA
SLEPIKNDDDAVRNFGIRYAVDLCQTLFTSGSATSIHLFTLNREASSR
>A0A6N9AFL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermaceae bacterium|TrEMBL
MQPPNRFDPPSSLDKGVSVLIWKATWRVSQPADPSVSKLSVAEQQSKPPPNVSFEFFPPK
SDSMEAKLWESVARLTPMAPRFVSVTYGAGGSTRDRTRRIVTKIAQDTPLLPAAHLTCVG
ATKEEVLGIAVDLWKAGIRHIVALRGDPPEGIDAKFEQHPGGFRDSIDLIEGIRNCEITP
GARFEISVSCYPEQHPHSRGWDQDIAFLRAKQDAGADRAITQFFFEPEVYFKFLDRARAG
GVTMPIVPGIMLQPNFKGMKRIADLCQVTLPDWLYEVFAGTGDDTVTREFITANVAAELC
HKLSDQGVNEFHFYTLNRASLALSTCRLLGLKPQTVG
>A0A422LQX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPHACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFPGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A3D4UZ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneola sp|TrEMBL
MKITEYIKQAKGKALFSFEVLPPLKGQNIQTLFDHIDPLMEFKPPFIDVTYHREEYIYKK
RENGLLERKTVRKRPGTVGMCAAIQNHYKVDAVPHIICGGFTKEETENALIDLNFLGIDN
VLVLQGDVRKPDRQFIPEPDGHSYASELLAQVVDLNKGIYLDGEIENAMPSDFCIGVAGY
PEKHETAPNMESDLRYLKKKVDGGADYIVTQMFFDNQKYFDFVNRCREKGITIPIIPGIK
PVTTLKQITLLPQLFNIDLPEALTQELEKCTNNEAARVVGREWTIQQTKELVEFGVPSVH
FYSMGKSTSVYEVAKEIF
>A0A0D0ET73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldibacillus thermoamylovorans|TrEMBL
MGLIQDLEKQILIADGAMGTLLYSYGIDRCFEELNVSNPQEIERIHREYIEAGAKIIQTN
TYGANRIKLARYGLENEVQEINAKAVEIAKKTVKTSGKPVYVLGTIGGIRTFQKAIFSTN
DILQSFEEQLDILLKEQVDGILLETYYDLDELKAVLEVARKKTDLPIMANVSLHEKGVLQ
SGTPLAEGFNQLIDLGANIVGLNCRLGPYHMIQSFEEIPIPNGAFLSVYPNGSLPRMEDG
QLVYESDEQYFYEAAIQFVKEGVRLLGGCCGTRPEHIRAMAEAVKNLSPVTEKKVIKEKP
TIQLTQIQQVHEPSLVDIVKSRRSVIVEFDPPKTLPMSQFLSGVSALKNAKIDAITLADN
SLASPRISNVACAQIVKNRYHLRPIVHLTCRDRNLIGIQSHLMGLHALGIHDILALTGDP
TKIGDFPGASSVFDLTSFDLIRLIKQFNEGLSYSGTSLGEKTNFTVAAAFNPHVKIIEKS
VARLEKKIHSGADYFITQPVYSEELIMNIYDATKHLDVPIYIGIMPLTSTRNAEFIHNEV
PGIKLPDSVREQMKKVGNDKEQGKREGIAIAKHLIDVAFDLFHGIYLITPFLNYQMSVEL
INYIHEKEQMKVEREITSV
>A0A0D0II49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDSGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A6M2XQF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. punicae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1I7INM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira multiformis|TrEMBL
MESQKKFVPTFSFEFFPPQTAEGIEKLRATRRQLAQLKPKFFSVTFGAGGSTRDRTLETV
LEIQAEGLVAAPHLSCIGATRENIRAMLEQYRSSGIRHLIALRGDLPSGMAQGGEFRYAN
ELVAFIRREYGNAFHIDVASYPEYHPQARNAQEDLKNFKRKIEAGADSAITQYFYNADAY
FDFVDSCEAMGINIPVVPGIMPINRFSQLARFSDTCGAEIPRWIRKRLEGYGDDSASIRA
FGLDVVTDLCDRLLNAGAPGLHFYTLNSAGLTTTVWQRLGL
>A4FAF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)|TrEMBL
MTAVVDRLAGGRTGFSVEFFPPRDDEEERILWRAVRELEPLDPAFVSVTYGAGGSSRDRT
IRTTGRIAQETTLTPVAHLTAVNHSVAELRNVIGWYAAVGVCNVLAIRGDPPGDPNGEWV
THPEGLTYAEELVRLVRELGDFCVGVAAFPHGHPRSTCLDTDVEHLVRKIQTGAEFAVAQ
LFLEPEHFLRLRDRMSERGCDVPLLPGIMPITTPRVLRKFGELSGAPVPPAVLERLEPLA
DDAAAFRAEGVVLATELCERLIAEGVPALHFYTLNRSKATREVVSNLGLLPARA
>A0A3Q9MKQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Karamoja|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSTQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1C5QGM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MTKLTDIMNERMALSFEVFPPKTEKGMENLPGTIEHLCKYQPDYISCTYGAGGGNVGANR
EVCQMIKNAGTTPVTHFTVIKNTKEGMKDQLQQYLNEGVDHVLALRGDIPLGETTTCGDF
QYATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLESDIAVLKQKQDNGADYIMTQLCWD
MEQFKYWLDAIYSAGVTMPVDVGVMPILDQAATINMALSRNGCVMDHELCKIISQNWLFP
NPFAAKDAEGKPFDMFYDDKVKRFREAGIEYTIKQIDTYRSLGVNGIHLYALNKWKDVSE
IIDRAGLKTLI
>A0A181C6H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataeibacter rhaeticus|TrEMBL
MGLTAVELIPRDRETLLRDAGEVSQHFPDAQLINIPDLLRFPLRSWEAARLIRPIFPRVV
PHVRAIDIAPDAPLPGADDPGLREVLVVEGDPPTDLRHRTYPNTSESVIARYRREAPHLD
VYAAFDPYRRAPYKEMQAIERKKEAGAMGFFTQPIFDMRMLDLCMNWLEGETVFWGISPV
IGPRSRSYWETTNHVIFPHDFDPTLEANIAFARQMMDTVAQAGGNTYLMPLRVKLERYLI
PLRRA
>A0A6J7SMV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MNQQNGLEPRKSLLPRPTISFEFFPPKDEQGESNLHLTIEELKRFNPDFVTLTYGAGGST
RDRTVRIAAEIIARHQISTMAHLTCVGSTRKELTEILHEYSKVGVKDLLALRGDPTGGPT
SEWISTPGGFDFADQLVDLAAKMGGFNVGVAAFPDIHPASHGNFQQDIEVLLRKEELGAT
FAITQFVFDSERYAQLLFTLRDRGSKLTLYPGIMPVTNYMQIVRMLELSGGTMPSATRLK
FARYQNDPASIKELGVEVAARICEEVFEVGAEGFHFYTLNSAVTTSQVVSRLSMLNFSS
>A0A6J7FI51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSAPTISFEFFPPKDVAGEERLWGAIEALGPIAPDYVSVTYGAGGSTRDRTISITSEITK
RTQIPTIAHLTCVGSTQEEILHILTRYRDAGIKSILALRGDPEGGPRAPWVTIDGGLNHA
DELVALASEFGDFTVGVAAFPDGHPASHGNLDKDIDVLIRKEDLGASFATTQFFFDASKW
SALVARLDERGSKLPVIPGIMPVTNVKQLVRMSELTGTPIPDAMRKKFEAIESDADAVRA
LGIEIATEFCQKLLSAGAPGLHFYTMNTSTATSQIYENLALKR
>A0A8I2EYT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MRKQSFSVEIEANPGDLRQMKHYLHKWQPDFVSISNLSRYSYEEMVQCARYIQTDLNIPV
VIHLTGLTHTKEQIKKAFNELMDLNIRNFLLVRGNIHHNMRIENDFNYASDLIKYVNQLD
TDSKINVVAGCYPDIHVLADSLTEDIEYLKQKVNSGVDSLISLMCFDNKRIYKFLDKSRE
FGINVPIRIGIMPITDPFKRHYLAHNDVKMPEFSEEEDNLLENGINYAVNQINDLYEHNV
NGIHLYTHNDWMVSDRVFENIKQNL
>A0A6Y2IVS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADVTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8J8WW17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax benzoatilyticus|TrEMBL
MSTTPVSFEFFPPNTPVGADKLRTVVQDLAAVNPEFFSVTYGAGGTTRERTLDTVKAIAA
MGHEAAPHLSCVGSTEANIAEILATYREQGIRRIVALRGDLPSGTATAGEFRYASELVEF
IRRTQGDDWFIEVAAYPEYHPQQRYARRDLEHFANKVGAGANSAITQFFFNPDAYFHFVD
EVHKLGVRVPIVPGIMPIHNYARIAQFAARDGIEIPRWVALKMEGFMDDTASVRAFGIEV
VTRLCERLIAGGAPALHFYTLNQSSLSLEICRRLGLAQDA
>A0A6J7G6R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MAKISDLLSQGTSVSFEFFPPQTDEAEEVLSRTIGELESLHPSFVSVTYGAGGATRERTH
DLVVEINQKTSMTAMAHLTCAAHSRTELVDIISRYRDAGVENILALGGDLPNDSDLSAGE
LEHALDLVRLIRATGDFSVGVAAHPEPHPRSPSLAQDRDRGAEKLGEADFAITQFFFETR
HYFDLVEDFRARGVTTPVIPGIMPVLSIAGTKRMTELQGSEFPQWFLDRLRLVEDDPAAV
RATGIEEATRLCQELLDGGAPGLHFFTLNRSTATREIAANLGLPN
>A0A7K4M862|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marine Group I thaumarchaeote|TrEMBL
MTIRYEANPPKILPDVDTNESIEKFIEKIKIISKKCDAIHLTENVLGYQRVSPIEVGKII
RKEIPDIPITVSLRVRDKSEKEISEFVENCISIGFSGILALMGDPSQTGKPDLGQIPSTI
VKRLKEQGINSKIDLYLSISNKPDFSKIRKKLEANPKGFITQVVQNLEQVQNLSDNLKGF
SVIPIILFPSEKNQKSAKFLNLDFSSYSQGFEEFVKKVHNITGDVLITSPSDFNGLNEFL
EKSFS
>A0A173YAK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea longicatena|TrEMBL
MKISDILVEKTPHLSFEVFPPKTDAAYEGVLKATEAIAELKPSYMSVTYGAGGGTSKNTV
KIASHIKDKYNVPSLAHLTCVSSTKEEVHQVIDQLKAAGIENILALRGDIPQESEFPLPN
HYQYAYELIEDIKSQGDFCIGAACYPEGHVESEHKKDDIAHLKQKVDCGVDFLTTQMFFD
NNILYNFLYRAREKGVTVPVIPGIMPVTNANQVKRILSMSGTNLPERFKAIVDRFGDNPK
AMQQAGIAYATDQIIDLFANGINHVHVYSMNKPEVAAAIQANLSEILNK
>A0A5E9PI26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLESAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A6J6LCF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVVRTSYSLEFFPPKDEEGEARLWAALEALEFIAPEFISVTYGAGGSTRNRTIGVTEEVR
QRTKIPTVAHLTCVGSSRQEIISILHMYRAAGIRGVLALRGDPVGGPRAPWTPMPDGFTH
ADELVQLIHEFGGFDIGVAAFPDGHPSSNGDAKKDIDVLLRKEHLGATFATTQFFFDVSK
WEQLVYALQARGSTMPIIPGILPITNVKQLQRMAELGGTDIPPAVSSAFSAVEDDVDAVH
ALGIELASTLCEDLLRAGAPSLHFYTMNSATATKEIYRNLNNAH
>A0A2S4X4F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia marcescens|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLRDIAADYWNSGIRHIVALRGD
LPPGGGKPDMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A2X2EBK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella planticola|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRAIAEDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A060UR94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus ferrivorans|TrEMBL
MAHSVEFFPPKNAAGEERLREAISALLPLGPEYASVTFGAGGSTRERTFVTVAMIRQDYD
LEAVPHLSCIGSTEAGIREILRDYQKQGIRRIVALRGDLPEGMENPGHFQHAADLVAFIR
HFGGFDVYVAGYPEIHPRATSARDDVAHLVTKVQAGADAIITQYFFNTDAYLQLRDDLQR
QGVDVPVVVGVMPITNFEQISRFSAMCGADIPQYVRRRMEAYADDPQSQYQLGIELLSRQ
CQLLLREGAPSLHFYTLNQAEATTAIWRNLSL
>A0A6J7LYJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSLLREKLEFTAEPVFTAEFPSIDGGGMRAVQENAARLAPWFDAVNATDNPAAHAHASNT
TTAIAMKAHGLEPIMQIVCRDKNRLAIESDMMGASLHGITNISLLTGDDVTAGDEPEARR
VFDVDSAQAINIARIMTTGTYLSGRKINPAPDFYIGAVENAAAPPFDYRIQRALKKHRAG
AKFLQLQICYHPDRLEAFCKGVAEVAPDLKLIPTIVLLKGGKGLGFMNDKVPGIDVPVDT
LARVNSASNPSEEVFKLTFELAQHALSLPGVRGLHVTDFRHDDSLESFMIDLGRTPKR
>A0A5F1ZPT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira langatensis|TrEMBL
MKKILDIYKAAKSPVYSFEFLPPKTPEGEVKLFEAVRELSKVEPGFITVTYGAGGSTRDK
TIRLTSELAKQFALPAAAHFTCVGGNKDEIRNILKQIQESGISNLMALRGDPPKGEGHFK
RVEGGFGYASELISFIREEGFDFCLGAGCYPEKHPEAKSLEEDVENLKRKVEAGADYLVS
QLFFKNPTFESFLNLIRKKGIQVPVIPGIMPITSFSQIERFKMLAACEFPDELVSELEEV
KDNPEEFYKRSIHFSVGQCRELVKMGVPGIHLYTLNQSPASLDIVRELKK
>A0A165VK90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKAELRELLNLYKSAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A813Z7N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adineta steineri|TrEMBL
MYNNEIDPDAGHHPHVFKRAESDSGLQAKGCCLQTVKYVSLTEKIEKRIASNDRWYSLEF
FPPRTPSGAANLIGCFDRMAVGQPLFCDITWHPAGDPASNKETSSMMIANTMLNYCGIDT
MLHLTCYGAKKEHMLEYLYKAKEFGIRSLLALRGDPPVGEEWDPKKSDFRYGVDLVKFIR
QHFGDYFVICVAGYPQGHPDSTSYEDDLGYLKEKVDCGADFIITQLFFKPETFIKFESDC
RAIGITCPIIPGIFPIQGYASLRNIVRLAKLDVPKEILACIEPIKENDEAIRNFGVQTCL
DLCSALLDTGKVHGLHFYTLNREFATIEVLKKLGLWLEDHPLRALPWKKTSNSHTRSKEN
VRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGMLTDYHLFYMKIDATRDELLDEW
GRELTCEEDVWRMFACYIGGEKNTSNKVVRHFPWTDEELSLETTLIQNNLIEFNRRGILT
INSQPAVNGKPSSDPIVGWGTSNGYVYQKAYLEFFTSADNIPALRAVLKNFPSVNYHFVN
KSGESNETNTVDEQPIAVTWGVFTGREIVQPTVVDPVSFMIWKDEAFSLWTERWGKLYEP
ESRSHAIIEQIANTYFLVNLVDNDYVEGSCLWTILDSMFEYQKVSKKDGNI
>A0A2Y9BBC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalicatena orotica|TrEMBL
MKIKELFKQKTVLSFEVFPPKRTGSIHTIYRTLDELKELRPDFISVTYGAGGSENCRTTL
DIASAIRNDYGIESAAHLPCMGLTKEDILTQLGQFKEAGIENILALRGDYVPGLESRGDF
QHADELISFIRENGDFHISAACYPEGHNESADIVADIRNLKRKVDAGASHLISQLFFHND
YFYKFRERCTLAGIDVPIEAGIMPVANKKQIERMVSLCGVHLPSKFVTMMERYEDNPEAM
RDAGIAYAINQIVDLISQGVDGIHLYTMNNPYIASRIYEAVHRLIAA
>A0A351R3C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp|TrEMBL
MKISDACNHKKSLSFEIFPPKKDSELKNIDATLDVLCELQPDFISVTFGAGGSLNCNRTI
ELAKKIKQNYHVEPVVHLTCLHYNRAEIDEFARILTAEGIQNVLALRGDRNPDLTEKDDF
KHASDLISYLKPKGDFCFLGACYPECHPESANKIEEIRHLKEKVNAGAEVLLSQLFFDNT
QFYRFVEDCRIADINVPIVPGIMPVINAAQIKRMITMCGASFPERFQKIIHRFEDNKAAL
FDAGMSYALSQIIDLLANDTDGIHLYTMNNPVVARRICEGIQHII
>A0A093S722|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium polaris|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWESGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTSMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A162ZE47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Didymella rabiei|TrEMBL
MHISEKLARSRAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDITWGAGGRHS
KLTTEMVKVAQTVYGLETLMHLTCTDMERSKLDDALNDAYQAGCTNILALRGDPPREREK
WEATEGGFHYAKDLVKYIRDRYGNHFDIGVAAYSEGCDDNDDVDQLIDHLKEKIDAGATF
IVTQMFYDIDIFLDWVKKVRAKGIDVPIVPGIMPIHTHAAFLRRANWTRCKVPPKWTEVL
EPIKNDDVQVREMGSELVAEMCRKLIDADILHLHFYTMNLAQATRMVLEELELLPDVESP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGVGLKGTNEQNIKLWGTPTSVQDISDLFVRYMQGDLGSLPWSEQAITEEANAIQKDLID
LNRRGFLTINSQPAVNGAKSSDPTFGWGPRNGYVYQKSYLEVLVSPEYISEIITRIERDP
EFTYYAVNKDGDLKTNAPSEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQDW
ANCHASTSPARYVIGDLIDTWYLLNIVHNDFHVTSGIFPLFDGLEVEGMGKKFENGITAD
VSTNGHADTNGSNGTANGDKPDVPQKDPKEAKDEKSLLATAKAAAVEVTNGIKNLAVSN
>A0A0L8L277|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces resistomycificus|TrEMBL
MALGTASTRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDRVAAAGCDTPIIPEIMPIASVKTVDRIPSLTNAAF
PDALKERILTAKDDPAAVRSIGIEYATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A529X0B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDRVIREFVDFGVTRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>A0A3S3JVQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>W9KVS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum Fo47|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDRIKAIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A442N7P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNDRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPYDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A439VTM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDSILHDDITETQVDMVK
TAH
>A0A0F8FAF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina mazei|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRFSASLEDASQLKGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDYPTCGDHPGSKP
VYDVDSVQLIELVRKLDTGVDFAGNKLDGGTSFCAGAVSGIDPEKTMQLIKLQKKVKCGA
DFIQTQAVYDIGMFEEFMDAVNYLEVPVIAGLIPLKSLGMAEFMNKNISGIHVPEEIMLR
MKDASSPMEEGLLIASETIKELTKLSRGIHVMPIGSHRNTARLLSLAGISQK
>A0A8J6R6H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichocoleus sp. FACHB-46|TrEMBL
MLNSSLFPSPSCFRNALQSGEFLVTAEVAPPKGGNAAHMLQMALLLKDRVHAVNITDGSR
AVLRMSSLAASIILLQHGIEPICQVACRDRNRIGLQADLMGAHALGVRNILALTGDPVKA
GDHPDARAVFDLESVRLLQLIFKLNQGFDCNDKLMPDGPTDLLVGAAVDPQLNSWSGLQR
RFDRKLAAGAQFFQSQLICDFERLEKFMTQIAVGSNKPVLAGIFLLKSAKNAQFINRNVP
GVSIPDEIIQRLERAADPLQEGITIAAEQVKLAKELCQGVHMMAVRREDLIPQILDLAGI
PPITQAAPAFQAAGS
>A0A0T6BEN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryctes borbonicus|TrEMBL
MKPHHLTIFFKTVGVKTRQLSLELCTNRKLNMQKIKEMSPPFCSVTWLDNTVDNINMHPT
IQLSQELIRNDVNVLIHLPGRIYNKVEMLEILKTIKDIGVKNILVVQGEKSLGESQDDFP
YARKLVEFIREKFSNYFCIGVTGYPSGHPRSASLNEDLLHLKEKVIAGADFIITQAIFDI
DTFRNFHTRCRDLEINVPILPGLFIINSYSSLMNMVKFCKLRLPDDVMKFLEEHKDNREI
VEEYGISSVVNILESFFSSNELAVHCVHIFTLNDLDILEKVLSNLSL
>A0A6P1A9Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kamptonema sp. SIO1D9|TrEMBL
MTTRFRRAIQAKEFLITAEVMPPKGGNPARMLKMAKTLQGRVHAVNVTDGSRAVLRMSSV
AASTILLQQGIEPICQIACRDRNCIGLQADLMGAHALGIRNILALTGDPVKAGDHQDAKS
VFDLESVRLLKLIAKLNQGFDYNDKPLTDEPLNLFCGAAVDPQLKSWASLQKRFERKLAA
GAQFFQSQLISDFDKLDKFMTQVAVNTNKPILAGIFLLKSAKNAQFINRCVPGVNIPDET
INRLANAAEPLQEGMKIAAEQVKLAKQICHGVHMMAVKREDLIPEILNLAGIAAVD
>A0A8J7M353|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomesophilobacter sediminis|TrEMBL
MTNGFLKRVREEVLVGDGAIGTMLYAKGVALEANFEHLNLVRPSLVRELHREYLDAGAQV
IETNTFGANFVKLSAIGLGSKVAEINRQGAALAREAARGRDAFVAGSVGPLGRGKAELAA
GSELDCFRAQASALAEGGVDLLILETFADLDELLFALQAARETGLPVVANLAYGEGAKLT
GGIEAEAAAARLAAAGADLVGANCGAGPLELLKTLKRIATVTDLPLAAYPNSGFPEYVDG
RYIYRATPEYFAGMAAEMAAAGACLIGGCCGTTPDHVRSIAAALRGLKPAPRTVVQPSAQ
AETGTGTGAAAAGFLADWGKRKVVTVELDPPKGLDCSGVIAGSRALKDAGADAINLAENP
LARVRMGNIALASLIRREVDIEVIAHITCRDRNLLGLQSDLMGASLLGVSAILAVTGDPA
SLGDDAAASSVYDLNSFTLIKLLSDLNRGVNALGNPIGEGTGFTIGAAFNPNGQKMDVQV
QRLEKKVANGATFVQTQPIYDLQRLDLMLEQTAHLDIPILPGVLPLVSGRNAEFLHNEVP
GIVIPEAIRARMAGKTGDEGVQEGLAIAREFIEAAFDRVGGFYLIPPFGKYRIAAELVRF
IKERGAR
>A0A7G7LD97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium NBWT11|TrEMBL
MTFGPCGGVTDDGGCEVGHGPCAFLPVPTVRWPGAARPRTGPEPHLLALMRQRPVVVADL
PAVALDRDSLERAADRVVGHVDAVLLGDHGAARVQFSPTYRASLVQARGLPVWQGLNCRD
RNRVALEGELAGLADLGVGAVHCVTGDHTATGDRPDAQPVFDLDSTQLAAAARAAGVLVS
VGETPHGPPAERRPHRLVEKVRAGADVCFVNHAGSVEALRSFVERATDAGADVPFVACVA
VALDPGSADQLRRFTSLRLPAGHLAGIESARDPRRAGIAAAIALAESYLSVPGVRGVDLS
GVPTPGAELTTATALAEIGRALT
>A0A3B8LLH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MTHEWDTFKLMKIIDKINRCKQTGEHCFSFEYFPPRTQAGVENLYARIDRMGRLHPQFID
VTWGAGGSTAERTMEIVTHTQNLSGLETMMHLTCTNMSRKDIAAALCTARENGIQNILAL
RGDPPIGEENWEQHGDGFSHAIDLVRFIREEHGDYFGICVAGYPGGHIENPSYERDMHFL
REKVDAGADFIITQLFYDVDLFIQFMKDCKKMGIDCPILPGIMPIHSFNSFNKLTQFCRD
IPEEIVANIQAIRSDDEAVKDYGFTLVKGMCERLLEAGVDGLHFYTMNLESIVTHLVDEL
NLIPEQVQRTLPWRRSANEKRLQEEDVRPIFWANRPKSYIQRTMEWDEFPNGRWGDSRSP
AFGELVPHPWGHVQVHPKRRKKMWGEAPETFEDVKSVFLKFCEGDIDAIPWFDSPLELES
GRILEQLLKLNEAGLLTINSQPSVNGVPSDDSSVGWGSPGGYVYQKSYVEFFIDGRHIET
LIKVLKRHPSISFQAINKEGTVYSNCDTVNAVTWGVFPGKEITQPTIVDPDSFVVWKYEA
FDLWLYVWGALYPAESPSRELFQQIYKEFYLVNVVDNDFVKGDIWSVLDEVVKAISS
>F6ET71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium chlorophenolicum L-1|TrEMBL
MTLGFPSVEAAQAWQAPLYADLAGDVNVSFEFFPPKSEKMEEQLWSAIQTLTPLAPKFVS
VTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASRAEIDEVADAYWEAGVRHIVAL
RGDPPEMGAKFEPHPTGYSGAAELVEGLRKRHPFEISVAAYPETHPDAQSAQSDIDNLKR
KLDAGATRAITQFFFEPETFFRFRDTVAAAGIDADIIPGIMPVSNFAAVQRMSAMCNTDV
PGWMGKLFEGLDDHAAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVATNAV
>A0A7Y8TK85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia pini|TrEMBL
MTERINVDRPFFAVEFFPPKDDRGEAELWRAIRRLEVLDPAYVSVTYGAGGSSRDRTVRT
VERIATDTTLCSMAHLTAVSHSTDELRHVIGSLAAAGVRNIMALRGDPPGDPLGEWVAHP
EGLEYADQLVALIKRSGPFCVGVAAFPYGHPRSADLDADTERLVGKFRAGAEFAVTQLFL
EPDGFLRLRDRVAAAGFDQPIIPGIMPLTSEKTFHKGPELSGSPLPAALVERLAPYSGDT
AAFRAAGMEVTGELCERLLAEGIPGIHFYCLNRSTATTELVERLGLASRHEGTRLSTPA
>A0A0T6BEK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryctes borbonicus|TrEMBL
FEALYCYDKGTVVEKDDSKCDFPYGLEFLQFLKAEFGDDFSFGTSGYPIGHPTSEDPIKD
IGYLKKKVDAGADFVLCQGVFDLQTFKDFYKRCREQHNIDVPIIPAVYAINSYAVLKNLM
NFCKVVPPNYLASMERYQNDEEKITNYSIKYVSDLITALLKDTEISIPGVHVSCFNNLTL
VRQVFEKLDFADLKVCQRE
>A0A8H5XFC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium denticulatum|TrEMBL
MLTNRPRTRQRAYKKPPALDVPNIDEDAAERKRVLNVLAQRRYREKKRLDRLKTKSAGSN
RSQNSEPQDETVPNPEGRVSKDDVYEIPTLQSSLESTIPEPNLSIPPTTDADILAGFDLN
LTSWNSLGDPLQDLAFAPILPDPNTVPGYLHEDNTRGDSATNAHHDLSADFAVADMTMFI
DSSSLSSSPPSSEGQTFPDSYQLPLLQLTLLKAVMRIADRLNLKPDLWDLGGNSAFNTGT
ATPASLLPPSWQPTPSQVAIPHHPVIDLLPWPGVRERAIFILSLPDELRPPRAQGALAIV
NFAYDVEDTAEGVRIYGDDPYDPEPIKSTVSRLIADVTARFIVLGLSPIKRGAAEYNGNQ
FNGRSRYLHSVKWSSSPIDFTMHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMD
RMYNLGPKFIDITWGAGGRIAELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKA
YKAGCTNILALRGDPPRAQDKWTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDD
NKNEDELLDHLKEKVDMGASFIVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYA
SFLRRANHMQAKIPQEWLDALEPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMN
LAQATRMLLEELQWAPCAERPLQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDW
DEFPNGRWGDSRSPAFGELDAYGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIES
LPWSEAPLTTEADEIREELIELNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSY
LELLVHPDVFDKMITRIENHPDLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPT
IVESISFLAWKDEAFRLGVDWAHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFE
LLKGLEVKDLTTPATPLTESVVNGAVDTEPIANGAAATAVAN
>A0A1A7QIN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. QSSC1-22B|TrEMBL
MQEARTALDAPLFSGLPGDIDVSFEFFPPKSEKMEAQLWASIKELAPLDPSFVSVTYGAG
GTTRERTHRTVARIIEEAGLPAAAHLTCVDASKAEIREIAEQYWEAGVRHIVALRGDPPD
QARKFAPHPEGFASAAELVAGLREVADFEISVAAYPETHPEADCPASDLDNLKRKLDAGA
TRAITQFFFSPDTFFRFRDAAQAHGIDAPIVPGILPVTNVARAREFAGLCGAAIPDWMDG
LFEGLDSRPAARQLVASTLAAELCRRLYAGGVREYHFYTLNRADLSFAICHMLGLRPEGD
S
>A0A3D2B9E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPHWMAKMYE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2X2YEE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium perfringens|TrEMBL
MNIRELFDKKEFVFSFEVFPPKESTSIKNIYKTLEEIQELKPDFISVTYGAGGNFTSNRT
IELSSIIKNKYNLETLAHLTCIGAKRKEIEQTLNILKSKGIENVLALRGDKRENIISEYS
SSIDLIKHIEKYRDINIVGACYPEVHPEAIDNNKDLEFLKRKVDAGANHLISQLFFDNNI
FFDFLESCEKKGIDVPIQAGIMPVVNKKQIERILSLCKATFPKKFMKIINKYEYNKEALR
DAGIAYANEQIIDLISSGIKGVHLYTMNNSYVAKNIVSGTKNIINSVNKKIL
>A0A1G3DTH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium RIFCSPHIGHO2_12_FULL_40_16|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A252DR71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. RF31YmG|TrEMBL
MSDTQSTTVLNAFRRAAQAGEFLVTAEVAPPKGGDPTHMLQMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQHGIEPICQIACRDRNRIGLQSDLMGAHALGIRNILALTGDPVKA
GDHPDAKSVFDLEAVRLLQLIRKMNQGFDSNEQSLTDGALDLFTGAAVDPQCASLSGLQS
RFERKIEAGAQFFQSQLITDFERLEKFMDTIAAGYKKPILAGIFLFKSAKNAQFINKCVP
GVNIPQHIIDRLAKAKHPLEEGVKIAAEQVQIARQLCHGVHMMAVKREDLIPEILDLAGV
APVNLVLTK
>A0A0S8IJB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium SM23_72|TrEMBL
MTFREKILAGQFLLTSEIGPPKGIETNQLLEDAELIRARVDAINVTDLQSSVMRLGSLAV
CSLLKQKGFEPIFQVTCRDRNRLALQSDILSAAALGIENLLILTGDHTTMGDHPEAKPVF
DLDSVQLLGVVRKLQEGLDMKGNKLEGAAPKFCVGAVVNPGADPIEPQIIKMEQKIEAGA
EFFQTQAIYDVKIFENFLNKIKHLKTTILAGIVLLKSAGMAKYMNKNVAGVFVPDNLIKE
MEETKDKSAKSIEIAARIIMELKPMCQGIHIMPIGWDKKVPLVLDAAGL
>A0A5C0A3V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter thailandicus|TrEMBL
MPAQTGPLPAISFEFFPAKTEKAAATLLENAKTLAAFGPQFMSVTYGAGGSTRDRTLATL
KDMVRETGAPLAGHLTCVGASKEEVNAVAQAYWDAGVKHIVALRGDPPPSAGGIYEPHPE
GYAGAVDLVRGLKEIAPFEISVAAYPETHPAALNPQADLEHLRAKIDAGADRALTQFFFE
AETFLRFRDRAAAIGIERPIVPGILPVGSAAQAWKFAEMCGANVPKWMRDLFDGLDETPQ
TRALVAATVADRLCQTLKAEGVEQFHFYTLNHADTASALCRLLGCRPL
>A0A1Z9Z0X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter populi|TrEMBL
MSKHIPISFEFFPPKTDVGAEKLKVVHQQLQLLQPEFFSITYGAGGSTRERTLAAIEEFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHAGDHFQIEVAAYPEMHPQADSFDQDIQRFIEKVQAGANAAITQFFFNPDAYFYFI
DRLQKAGITIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSKSIQAFGHE
VVLKLCERLIAGGAPSLHFYSMNHTEPTRQLVVDLGLA
>A0A0S8IB43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium SM23_61|TrEMBL
MRFQQRLAQGKFTLTCEISPPKGTDAAERIAEAQTLKGRVDAVAVTDGKGSVMVMSALAL
AHLLQDHGWETLLYLSCRDRSRMALQAELLGAAALGIRNLVVVTGDYASLGDHPQTKPVF
DLDSVQLLRAVRGMREGKDMMGNPLHGSPDFFVGGTVSPVPGSEAALDLQLMKMEKKIAA
GARFFQTQPVFDLARFERFLKRASGLGVPLLAGVMPLKSVSMARFINKNMPEMAVPEDMI
DELSQAADRVQVAVSLCGRTLRQVRNLCPGAHLIPAGWGKRIPAILDAARL
>A0A149SM04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter thailandicus|TrEMBL
MPAQTGALPAISFEFFPAKTEKAAATLLENAKTLAAFGPQFMSVTYGAGGSTRDRTLATL
KDMVRETGAPLAGHLTCVGASKEEVNAVAQAYWDAGVKHIVALRGDPPPSAGGVYEPHPE
GYAGAVDLVRGLKEIAPFEISVAAYPETHPASLNLQADLEHLRAKIDAGADRALTQFFFE
AETFLRFRDRAAAIGIERPIVPGILPIGSAAQAWKFAEMCGANVPKWMRDLFDGLDETPQ
TRALVAATVADRLCQTLKAEGVEQFHFYTLNHADTASAFCRLLGCRPL
>A0A562KFV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium cheniae|TrEMBL
MKVTEHIQNANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LENGLLQKKVVKKRPGTVGICAGIQNKYQVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGHAYASELVTQISNLNKGIYLDEDLQNSTKTDFCIGVAGY
PEKHMEAPSLDSDIHFVKQKIKNGADYIITQMFFDNKKFFDFVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSVELPDDLIMAVVKAKDNDAVKQIGIEWCTQQSKELVAAGIPVLH
YYSMGKAENVKAIAKEIF
>A0A7Y1IJB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas panacis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLATYHPDFFSCTYGAGGSTRDRTINTVLQLE
SEVNIPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARHFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISNMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A8D5YRM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes sp. L3-i22|TrEMBL
MTTAITRPALLLRDFSLEMTGKDAAEVIDARGAIPPGTRINVTFLGNEDLPMRRAAARTV
REQGFVPVPHVSARRLTSCEDLKEFLAALSADGTQKEIFAVGGDPAEPHGPFPDALSLIE
SGLLEDFAVRRVSVAGYPEGHPDIADSALWSALKEKSTALQAHGLAGEIITQFGFDVDPV
LDWIARVRELGIDLPVRVGVPGPAGVRRLMRYAARFGVGTSASIAKKYGLSLTNLMGTAG
PEKFLRALATDYHPDVHGQVKLHFYTFGGLRATSDWIHDFRKAS
>A0A3R6VM36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OF10-22XD|TrEMBL
MKLKEYIQTKRIIADGAFGTYYISLYGDGSRAENGAGLSNLPELANIKAPERVIGIHTEY
IEAGAQFVRTNTFASNTKSLSADMEKVKENIRAAVMCAKMAAGKVDREIYLAGDIGPIPV
EGMLHSDRLTQEYIAIGETLLSQGIDIMLFETFPELETILPAVTYLKENHDCTILVHFSV
NQFGYSNTGLSAKRLIAEANACPYIDGTGLNCGVGPGHMEKLIRKIAPDDTTFLSVFPNS
GYPKYLNNRLTFTDNAEYFTEKMEEIAALDVGIFGGCCGTTPEYIRRIAAGISADHPVRK
TETEAEKITAPEHPAYGFMERRVKEPAHKLIAVELVPPLNANDEKLLDAAHILKNAEVDV
VTFPDSPSGRTRADSVLMAEKIRLETGLCVMPHICCRDKNAIAIRSTILGASLNHITNFL
LLTGDPVPILFRQTTKSVFNFDSVGMMKIVQEMNSDTFTDHPVTYGGAINHNRMNTKAET
ERIRRKMAAGATFFMTQPIFSAEQADVIRQMKKETGATILVGLMPLVSRKNAVFMKNEMT
GIEIPDTVIERYREDMSREEGEACGAQIAREFMAMTDDFADGYYFSFPFNRVHMLKKILK
>A0A7X8V175|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramlibacter sp|TrEMBL
MTAPSISFEFFPPKTPEGAEKLRVARQQLYTLKPEFCSVTYGAGGSTQKGTFDTVQEILQ
EGMEAACHFSCVGATRDSVREELETLRQMGVKRLVALRGDLPSGHGLGGEFHHASDLVSF
IRVETGDYFHIEVAGYPEIHPQARSPEADLRALKSKVDAGANGVITQYFFNADAYFRLVD
EAATLGVSAPIVPGIMPITNSSQLIRFSDACGAEVPRWIRLRLQSFGDDTASIKAFGHEV
VAELCDQLLQGGAPALHFYTMNQSGPVTALCKAVGV
>A0A517P3X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alienimonas californiensis|TrEMBL
MHLSDVYADRFGLSFEMFPPKTPAGDEALRVELARLAEYDPAFVSCTYGAGGSTRDRTLD
WCRELKSDFGQNVTAHFTCVGSATGDMAEWLDAAQEAGVSNIMALRGDLPEGGPDDAPWQ
PPAGGFRYANELVAFVRERFPEFGVGVAGYPEKHPECGDPETDLANLKRKVDAGADAVFT
QLFFENDHFLRFRDACGEIGVDVPIVPGVMPVTDFARIKRITAMCGSTFPRKFSAALEAV
KDDPVGQFEIGVDWAVNQCRGLMEEGVPGMHFYVLNKAAATEQILDGMNLAPVRA
>A0A3D8H293|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter flavimaris|TrEMBL
MTLVSERQPFNRPDEEAAARFRDLVRSASIEATPRQILTTEHLPDLLPAGTCVYVPFLPK
GQFSDTLEASRRLLDLGMQPVPHVPARMAQSRGQLRDWLAQLDESGVDRLLLIAGDSDAV
AGPFPDTLAVLESGLLAQFRFHGIGVAAHPDGHPMADRATLAQALSVKREYARTTATRLW
VVTQFTFDAEVVIDWLQGLGNILEEVPVYIGMAGPTRVKTLIAYAAMCGVGASARMLLRR
PGSARMLGAWKPDDMVRALVQYCLENPETLLRGIHLFPFGGLRQSAQWIRDHSGSCENNR
EAVP
>A0A0S2SMH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas schubertii|TrEMBL
MGFHSARQVEALNQSIADLSGDISVSFEFFPPGSESMEQTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGVEKPDMYAADLVALLKAEANFDISVAAYPEVHPEARSAQSDLLNLKRKIDAGADRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLTKFAGFTNVKLPRWMHQRFE
GLDNDQATRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKSV
>A0A417TVV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. OM04-18BH|TrEMBL
MKISELLKQDKVTLSFEVFPPKTSSSYESVARATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAKMVQKYKENGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCIGGACYPEGHVEAANKTEDILHLKEKVEAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVIAGIMPVTNVNQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQASLSEILG
>A0A7W7C941|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crossiella cryophila|TrEMBL
MTSVVDRLCSARPSFSVEFFPPGDENAERQLWRSIRDLEPLEPSFVSVTYGAGGTKRDRT
IRITGRIAAETTLTPVAHLTAVNHSVAELRNIIGWYASAGVTNVLALRGDPPGDPHAEWI
PHPEGITHAEELVRLVRGLGDFCVSVACFPNGHPRSTGLEADADYLVRKFEAGASYAVSQ
TVFRVEEFLRLRDRVAARGIDVTKVPLLPGLMPITSVKGVRRMAELSGDPIPPEVLSRID
PIAEDPAAVREEGVRIATELSQQLLAEGVLNLHYYTLNKSTATREVLENLGLVPARA
>A0A6J4DXV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas tohonis|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNTARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVKVPTAPHLSCVGDSKADLRSLLEQYKAAGITRIVALRGDLPSGMGMASGELRHANEL
VEFIRAETGDHFHIEVAAYPEVHPQARNFEDDLANFARKAKAGADSAITQYFFSADCYFY
FVDRVRKLGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDLESIQAFG
EQVVSEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1V4X709|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium PtaB.Bin038|TrEMBL
MLIRDLFNQKKRTLSFEVFPPVREGNLESLFATIAELKELNPDFISVTYGAGGGTRDKTI
EIAARLKNEIRSEALAHLTCVASTRDDIARILEDMKAQNIENILALRGDPPRGEEKFVRP
AGGFGFANELVEFIQAHNGFSIGVAGYPEGHPEAPSLDDDLKNLKRKVDAGADFIITQLF
FHNEDFYRFRDRAMAMKIRVPIIPGIFPILNYKQILRITELCGAKIPEALGERLCRLKDK
PGEVEKYGIEYAQQQAWDLIRNEVCGLHICTMNQSRAARKIVRELAL
>A0A5D3K2Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium rifense|TrEMBL
MTGAMTDLKTPAHTDGQDGHLATKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVS
VTYGAGGSTRERTHSTISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGL
RGDPAGGIGTPYAAHPDGYQSSDALVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTL
KAKVDAGATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARAFVTRAGT
TVPDWFAAKFEGLDDDAETRKLVAATVAAGQVQKLAKNGVDTFHFYTMNRADLVFAISHL
LGIRAKSAQKAA
>A0A2T2SLB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QH_2_67_10|TrEMBL
MDLQLVGVGGYPEKHIEAPNLTWDVLRLKRKVDAGADYITTQMFFDNDAYFEFVERCRDV
GITVPIIPGMKILSRKRHLQFLPSFFHLSIPEALAAEVEAADDKEEVERIGVEWAIQQAE
ELMDAGAPAVHFYIMSSARLAKRVVEPLRENRRKKKGQQAPVEEQPAPEGQPAPVEEAEE
VDE
>A0A1E5HZQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium sp. MDAL1|TrEMBL
MKIKNIFEEKEVVFSLEVFPPRPDVPIENIYQTLEELKDIDPDYISVTYGAGGGLRKNRT
CELSSIIKEKYDVEALAHLTCINSDQETLNKILARLESKNIENILALRGDKPVDGEALGD
YNYAYQLVEHINKHNDFGVAAACYPEGHLETESLDQDLEYLKQKVDHGVDYLISQMFFDN
SLFYKFRNKAEKKGINVPIEAGIMPVINKKQVGRIIELSDAYFPKKFQKILDKYEDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKAD
>A0A4V6Q5N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. KS 21|TrEMBL
MSARPTPYPERPVPAPVTGGGLAELLRRVRYEVLPAKTTEDKVLAHVPADVPVTVTASPA
KGLGPTLDLATRLAGHGYRVVPHVPARQVSDAAHLTDIVDRLVAAGIEDVFVPAGDADPP
AGEYDAALPVLRRLGELGSPFAHVGITGYPESHPLIADDVTVQAMSDKQPHATYIVSNLC
FDPATLRQWLARVRRRHVVLPVHVGIAGPVERAKLLSMATKIGVGESAKFLTRHPSWFLR
FAAPGGYSPERLLRRSAPALGSPEAAVAGLHLFTFNQIAETERWRRAMLERIGG
>A0A2B7YXN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. animalis|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSLEKPDYISVTYGAGGNTKGRTV
EIADRIKRQNGLESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEKGD
FNYARELIEYIHKKKGNKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRHE
>A0A117PM25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces curacoi|TrEMBL
MALGTASIRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGEWVPHPQGLTYAAELVELIKASGDFCVGVAAFPAMHPRSADWETDVRRFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAAGCDTPIIPEIMPIASVKTLERIPSLTNAAF
PAALKERILTAKDDPTAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHPPQA
>A0A5C2ELV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzicola|TrEMBL
MPPHHHEKTARPVISIDMPSHTRAITDAYSLEVSVKDIGALTKAAPRLLPGSSMFIPYLP
GQHDAARLAAAQLVRSLGFEPMPHLSARRIGAPEELQAFVARLVDEAGVTRCFVIAGDPS
TPKGPFADSLSLIETGVFERSGIRTIGVAGHPEGHPIMRTAEQWDVLERKCRSIQERGMA
PLIVTQFGFDADMVVTWVEALRARGIPHPVRVGVPGPASVAVLARYAASCGVGACASVLS
NYGISIGKLFGNAGPDRFVDRLASRLTDAHGDIRLHVFPFGGIAQSVAWVAQYRSRASSQ
DRMSSVRADQA
>A0A1F3ES75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWB2_41_8|TrEMBL
MKVIDIINQSNKTVFSFELLPPLKGNDASKIYKTIETLVDFDPKYINITTHRDEMMYIEL
PDGRIEKRTVRKRPGTVAIAASIQHKYGIPVIPHILCGGFSKSETEHVLIDLNFMGISNV
LALRGDGNKGEHVFRPDANGHSNANQLVEQIVNLRNGKYLEADLRNTHPMDFCIGVAGYP
EKHFEAPNAETDLQYLKQKVDAGADYIVTQMFFDNQKYYDFVTKCRAIGINVPIIPGIKP
INLKNQLTVLPKLFSIDIPQELATELGKCKTDDDAKIVGTEWAIQQSKDLVANKVPSLHI
YTYGVSDNTRKIVESVF
>A0A2K8LUT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. AA4|TrEMBL
MADHTLQQLLTGADSGVLLFGITPPRLSNSPERIQEITAATLARLSELDVDGLALYDIDD
ESDRNPEERPFPYLPTLDPAVYHADYLSEWDRPAVVYRCVGKYPGDELRDWLRTADTDRV
LSVFVGASSKGKEVHTRLSEAQALRREVRPDLLLGGVAITERPDEHLRLIAKQRAGCAYF
ISQVIYSADAAKSMVSDYFYTCREQGIEPKPVLFTLSVCGSAKTLAFLKWLGVHVPRWLE
NSLRHADDTLAESYEQCLANARELAAFCRKLGTPFGFLVESVSIRKVEIEASVSLAREVG
ELLGRTG
>A0A0P6XEY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolinea tardivitalis|TrEMBL
MNLSEIFKQQKVHFSFEFFPPKTEEASHALLETISKLSPIQPSFVSVTYGAGGSTNQLTQ
NLVIRLKQETPLNVVAHLTAIGASRDEIKAQLDRYSAAGIENVLALRGDPPKGNPSFAPA
ADGFAHAADMVAFIKKNFPHFSVSVAGFPEGHPETPNRLLEMDYLKAKVDAGADCICTQL
FFDNRDFYDFCERCEIAGIKVPIIAGIMPVTSISGLRRMSELALGARIPAKLLRAVLRAR
GDDAVEKIGIHWSTQQVFDLYDHNVSGIHFYTLNHSKATLKIYETLGMSLGEAWHIPNHN
GG
>A0A1H9FUB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chelativorans sp. A52C2|TrEMBL
MTMNEAERGANGNAEGLAVSFEFFPPKSDEQLPGLEKAAERLARFRPQFVSMTYGAGGST
RDRSFQAVRLIIEGTALPTAAHLTCVGQSREHVAEVVARFRDLGVSHFVALRGDSEGGLG
EPYRPHPEGFQDTADLVAFLKEVPGTEVSVSGYPERHPQSADWAEDLDVLKRKIDAGADR
AITQLFFDNDLFEAYLERVRAAGIAIPIVPGILPIHKFSAVQGFAGRCGATIPERIARRF
EGLETDMDAHRRTAVEVAAEQVIGLRQLGVDFFHFYTLNKGELVEATLESLGLRAAEKQA
A
>A0A6J4Q334|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Rubrobacteraceae bacterium|TrEMBL
MQDRRSGLVEALRRPRYEVIPLPGIEVAVAEHVPKNVKLTVTASPKKGIEPTLALAERLS
AEGFGVAPHLSARLVRDRAQLGEILARLHGAGIRDVFVVAGDAPEPAGEFEGSGALLEAM
EEIGHGLDEIGITGYPESHPLISDEATIQAMYRKEPYATYITSQICFDTDTINDWVLRVR
RRGVGLPIFVGMPGAVNMAKLVRISSNIGLGESARFLQKYGNWFWRMFMPGGYSPDALVE
GMSASLGDPERKVRGFHIYTFNEVQKTEAWRLGALERAGATTQERHKEPTL
>A0A6G4U5A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces coryli|TrEMBL
MAHGIASTRTDRALTVRELLASGEQSFSFEFFAPKTPKGERTLWNAIRRIEAVSPTFVSV
TYGAGGSSRDGTVRATERIATDTTLTPVAHLTAVNHSVAELRNVIGQYADAGIRNMFAVR
GDPPGDPNGEWITHPQGVTYAAELVELIKESGDFCVGVAAFTNKHPRSTDWESDIRYFVE
KCRAGADYAITQIFYTAEEYLGLRDRVAATGCEVPIIPEIMPVTKVTQIERFAQLSNSPF
PQDLADRILAVKDDAAAVRSIGIEYATKLCERLQAEGVPGMHFITMNHSTATLEIYENLG
LRPQS
>A0A1X6MET6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus ayderensis|TrEMBL
MGLLDDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIESGAEVIQTN
TYGANYVKLARYGLQDDVKKINEAAVELAKKAAKGRAYVLGTIGGLRSTNKSTISLEEVK
RTFREQLYVLLNEGVDGLLLETYYDFEELQTVLSIARKETTLPIIAHVTLHDIGVLQHGM
PLAEALTELEQLGADVVGLNCHLGPYHMLRSLEEVPIPTRAFLSVYPNASLPQYRDGRFI
YETSEQYFEETARAFREQGVRLIGGCCGTTPKHIAAIARALSDRTPVYKKEVKQRHPIVV
QEEKQTTAPSLADIARTRRSIIVELDPPKKLGLTTFLEGAKALKEANIDALTLADNSLAT
PRISNVAVGTIVKQQLGMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRL
EKKIECGAHYFLTQPLYSEKQIEDVYEATKHLPTPIYIGIMPLTSARNADFLHHEVPGIT
LSDDIRNRMAMCANDRVQSTKEGLAIAKALIDAAFDLFQGIYLITPFLRYDMTVELVRYI
HEKERLAKERTVYHG
>A0A7C1C9P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MMQISEILNTRDRGISFEFFPPKTGEGMSALMKVAVELAEYDPLYVSVTYGAGGSTQDRT
RKLLIKLKEETDLTVMSHLTCIGATGEMMDSLLRDYRDNGIDNILALRGDPPQDAEDYDP
ATGEFRYAKDLVEFVGKYNYFSIGVAVYPEGHQEAPSLEADIEYTKMKVDAGADFAITQM
FFDNRYFFDFLERA
>A0A7V1V6M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSRDPRRLRDTLERGEFAVTVEYNPPKGTNVSALLESAKGLLGRVHAVNVTDNTAAIMRA
SSLAICRLLYEMGHDPVMQMTCRDRNRLGMQSDLLGAHILGIRNILCLTGDYPTVGDHKD
AKPVYDLDSVQVMQLVEGLNQGKDLAGHKLDGATDFLIGGAVTPEMDPAGPMLVKFETKV
RAGARFFQTQGVYHPETFAGFMRAVRPLKVRVLAGIVLLRSAKMAEFMNANIPGMAVPDD
MIAELRAAGPKRELDAGVEIAVRTIQAVRPHSDGVHIMAIKAVDRLPEILTKAGLG
>A0A6P3I021|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bison bison bison|TrEMBL
MDRPKPKVFPVGHCCPSLGMRASEAGSGRLSVPPSIRNSAMVNEPRGNGSPGPRWEGSSS
GSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRFD
RMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITGH
LNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKGH
PEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCPILPGIFPIQG
YHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFY
TLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLSG
EPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGWG
PSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNL
VDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>A0A3G2T0L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter wuhouensis|TrEMBL
MSVFLKYADETQKQFCIWVEYLCSTIKYQPVKQTIAGFPAMVTLADRVHSDEDPDPISVA
AQFPKEIEKLLHFSGKGRDIREFEHFLDQVEQFGYRNLLLLSGDKLKNHQYGEKGFTERT
RYLESVNAVMAAKKRDKFKIGVAYNPFKYSEAERDAQYFKLHKKIQAGADFLITQLGFDL
DKIKQTQQYLVGDYPYFPLIACVMPLTLRRAKFILKHQVAGIVISKHLIHVLEQEYQADP
IQAEKNVYARCALQILICQHLSYVGVHLSACYKLDEQQQLEQALQHYQGLSLEECEMAWN
ILWQAETEKVFQPEVKVFNRKVSTNQRLKYKTMQFMHNILFDSRPAMGIGRFVFKASFWD
RPKANQFLLKVEHLSKYHLVGCESCGQCRLHETLYICPETCPKGLANGACGGTTLDRCEF
GDRECIHSTKARLAKAVQQIEVLKTELIPTVAIETRDTSSWRNWYLATKA
>A0A1Z4HDX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix sp. NIES-2100|TrEMBL
MSDTQSPTVLNAFRQAAQAGEFLITAEVAPPKGGDPKHMLDMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQHGIEPICQIACRDRNRIGLQADLMGAHALGIHNILALTGDPVKA
GDHPDAKGVFDLEAVRLLQLIRKLNQGVDSNEQPLTDGALDLFVGAAVDPQCASLSGLQS
RFERKLQAGAQFFQSQLITDFERLEKFMDTVAAGCNKPILAGIFLLKSAKNAQFINKCVP
GVNIPQHIIDRLAKAKHPLEEGVKIAAEQVQIAQQLCQGVHMMAVKREDLIPQILDLAGV
APVNLVLTK
>A0A7V0NQ21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MNFKEALNSEKFVVTAEVGPPKGTDIKEMLHDAEALKGKLDAVNVTDNQSAVMRINSLSI
CKILLDMGHEPILQMTCRDRNRIGLQSDLLGASVLGIRNVLCMTGDHPNAGDHKETKAVY
DIESVQLLRVVDSLNNGRDMMGNEMKGATDFFQGAVVTPEADPVEPQLMKFEKKVAAGAN
FFQTQAIYDIGKFKEFMTYARKFPVKILAGLVLLKSAGMANYMNKFVPGIKVPQDLIDEL
KAAGKGNALDAGINIAARHIKQLKEEDVCDGVHIMAIGAEDKVPLIMERAGLL
>A0A1X1J772|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. dentisani|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNSETAKYIHQATHALFNHQSLG
>Q1ME09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae (strain 3841)|TrEMBL
MALKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTRAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESHDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRPGRETKSAGA
AA
>A0A2W6DPM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MTAVIDRLGGDRPVFSVEFFPPRDDAGESQLWQAVRDFEPLDPAFVSVTYGAGGSSRDRT
VRITGRIAQQTALVAMAHLTAVNHSVAELQQVIGRYAEAGIRNVLALRGDPPGDPLGEWV
AHPQGVHYAEDLVRLARSLGDFCVGVAAFPERNPRSPDAESDVRYLVAKLRAGAQFAITQ
MFFRPEDYLRLRDQVAAAGADMATVPILAGIMPITTLRGVQKMADLSGCTIPAAVRDRLA
TVGDDPAAVRQVGVDVASELCERLLAEGVPGLHFYTLNRSASTRAVLSRLGMAPAAATH
>G1WIU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella tanakaei YIT 12063|TrEMBL
MRVDQIFEQAKAAGAQPVSFEMFPPKGEMTLERAREVAGSFSQLNPDFISVTYSAGGSGN
NGATTKIAQMIDADFGIPSVAHLTCISLKRADLLAKIDEMRAAGIQNVLALRGDVPQGAP
TGPGCADYRYAKDIIPHLVDASFCVGAAAYPEGHIECDDLELSVRQLKEKQDAGASFLVT
QLFFDNQYFYRFRELAERAGITVPITAGIMPFMGKQQISRMVFMCGASLPSPVIKLLARY
EDDADSLRAAGIEYACRQLEDLAANGVDGLHIYTMNRADVAGAAMSALRA
>A0A428PYS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sp. AF-8|TrEMBL
MHIKEMLTDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRDQDK
WTAADGGFQYARDLVKHIRSTYGNHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKKVRERGVNIPILPGIMPIATYASFLRRANHMKAKIPQAWLDAL
EPVKNDDVAVRDIGKSLVADMCRKLLANGIHHLHFYTMNLAQATRMVLEELNWAPSAERP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTVQDIAQLFVRYLRNEIDSLPWSESPLTSEADEIRDDLVE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPSNGYVYQKSYLELLVHPDVFNDMISRIEGHP
DLTFYAVTKDGELRSNAPSDCPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDSNTPSRALIEEVMNEWYLVNIVNNDFHQNGTIFELLKGLEVKDLTTPATPKSEPE
ANGTEPVANGAVAA
>A0A2W6B3V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MIDLPESGGTGALAAALRAGHFAATAEIGPPRGANAEVVRRKAALLAGHVDAANITDNPS
GFIRLSSLAGCVIAQAGGVEAVVQLTCRDRNRIALQSDLIGAGALGIPNVLLLTGDHPRF
GDHPDAKPVFDLDGVQLTWTARELRDEGRLLSGRELTARPRWLIGAVENPFAPPREFRAR
RLGKKVAVGAQFVQTQFVFDVAGFADWMKQVRDLGLHERCGILAGVGPLRSLRALQHVSN
DVPGVYVPDDVGRRLRAVPEDRIADAGVDLCVETIQQIREIPGVAGVHVMAFGYERGIPE
ILERAGVGPRTRVSAVAGRGDEHAR
>A0A2N2E4P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-12|TrEMBL
MFIDNIFSAKKPVISFEIFPPKKDSPIETIYNTLEGLKDTKPDYISVTYGAGGSSTNRTV
EIAHLIKKKYEIESLAHLTCITSTSQEIDSILSSLKENDIKNILALRGDLPQDPAIAFPT
PLHFRYASDLISYIKSKGDFSVGGACYPEGHPDCESLDNDVINLKSKVEAGLDFLITQLF
FDNDKFYNFIDLMSKYGISNIPVSAGIMPVLNTKQIKHITALTSATMPKKFLRIMERYEH
LPEALKEAGIAYATEQIIDLLSWGIDGIHVYTMNKPEIAKKITENIFNIRKCITN
>A0A4U0W1G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodotorula sp. CCFEE 5036|TrEMBL
MVKISDKIRKAEREGRPWWSFEFFPPKTAEGWVNLYDRIERMTQLGPIFVDITWGAGGST
SEATTNFVKTAHSDLGLETCMHLTCTNMPVEMVDKALKEAYDSGCRNILALRGDPPRGVK
EWKPTEGGFNHAIDLVKHIRKHYGDYFCIGVAGFPEGHPDSESQEAEIRHFKQKVDAGAD
IVFTQMFYDADVFIDWGRRLRAAGITIPIVPGIMPIQTFSAFKRRTDFAGTIVPQELWDL
LEPIKDDDAKVREAGTQYVANMCRKILNADLGIHGLHCYTMNLSRGTEMLLEEMQFVPTA
DRVKPLPWRVSLTQKRRTETTRPIFWSNRQRSYLVRTRDWDEFPNGRWGDASSPAFGDVD
ALLAALPIKPQDAIDLWGKPVSLGDIAALFARFCRGDLKRLPWSDQPAAKETSRIAEQLA
KVNELGFLTINSQPRVDGAKSEDPAFGWGPINGYVYQKAYLEFFCPPQHVEELLEILNDN
PSITYHAVNKQGDFRSNTAPGPNAVTWGVFPGAEVIQPTVVDSAAFQAWKDEAYELGSQW
AQLYQETSPETQKLIHSVFDEYHLVNIVYNDYRDPDEDAVFKPFFELASKKGLAAVNGH
>A0A1H1EX74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora saharensis|TrEMBL
MSSAPSAPSHVLAGLLEDVSFEMTGKDIDGLTGARESLPRGSRINVTFLANEQQQQRLRA
VRAVRDAGFVPVPHISARQLESRAELEEYLAAIREAGSCDEVFVVGGDPASPRGPYEDSL
EVVRSGLLEQYGVRCVGIGGYPEGHPLISDAALWSALEDKSGTIRQRGLVGGIITQFGFD
VDPVLSWAEAVRQRGIDLPIRVGVPGPAGIRRLLRYGARFGVGTSAGIAKKYGLSLTNLM
GTAGPDRFLHDLARNYDAQRHGELKLHFYTFGGLKATSDWVTEFRRKEG
>A0A1B8P388|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas elongata|TrEMBL
MLPGHVSPGRLERVLRAGRFAVTTEIDPPDSADPAEVLRRAAIFDGYVDAINATDGSGAN
CHMSSVGVCSLLTRVGYATILQMSCRDRNRIAMQGEILGAAAMGACNLLCLTGDGVQAGD
HPHARPVFDLDSLSLLEMARRMRDESCFESGRPIDSPPGCFWARRPIPSCRPGLGEPSVW
PRRWRPARVSSRPSIASIPLSYGISWPKSPTSACWKGRIVSMCWSVWGLCLRRAVRAGYA
TMFPESIFRIA
>A0A1E9Z7P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC071B01|TrEMBL
MATVHPALSFELFPPRSQASCESLLRTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSDAE
LHRIGVKYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEY
A
>A0A522C5C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSFREILNSGKFAVTAEVGPPKGTDIKEMIHHMELLKGKLDAVNVTDNQSAVMRICSIAV
CKIAMEHGLEPILQMTCRDRNRIGLQSDLLGANILGIKNVLCMTGDHVSAGDHKGAKPVY
DIESVQLLNAVDGLNKGKDMSGNDLKGATDFFQGAVVTPEANPIEPQLMKFEKKVRAGAN
FFQTQAIYDIEKFKEFMKHARKFPVKILAGFVVLKSAGMANFLNNNVPGIRVPQTLIDEL
KAAGKEKALDTGMNITARHIKQLRDEKICDGVHIMAIGMEDKVPMIMEKAGLI
>E6M1H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobiluncus holmesii ATCC 35242|TrEMBL
MTIKDLYAAPRPAVSSLPESGATSRRTGSGRDLRVSYELYPPRNSRLTSQAWAGIDRLLD
SRPDYVSVTFGTSGTTPDASQSVLWHALKRSGRPVLAHLTCLGKTRTKLVGIIQDMMDLG
VRDFLALRGDEAPDSASGAAEPNEFDRAFQLVQLIREVSADYLGDAHAVSIAVAAYPAGS
IQTRTDAVQALVQKQAAGADFAITQVFYQARDYAELVQSATYQGVTIPIVPGIIPFTDMH
RLQRLEGLTGVPVPERIKSIANISDPAERILESLGATLNFVNDLIEANAPGIHFYTFNRP
RPVLDLVEHLRSRGFTHVDQEDSQDLLGLMNATMHRISP
>A0A7S3Y739|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heterosigma akashiwo|TrEMBL
AAATTEDQELRHLKSKVDAGADFILTQLFYDVGLFLAYVRRCRAAGITCPIIPGIMPIQN
YSAFVRMTAFCGTRVPPAVLAALQPLRADDAAVKRYGVELAVDMCQQLLAAGCPGLHFYT
LNLERSVREVL
>A0A8E0MH78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli HVH 70|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A533WYH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MKISFELNPPKIVKGDMFDLAQLNADMEAMADRALRLASLVSGIHLTDSVLGIPRVSSVT
AAGYIKNRVSTVKLNCSIRVRDRNFTSLCQAVSDAILIGIDSVLLLMGDDPADGLSDSGL
RPSAAVRMLRKEGYSSSIKLDLSFPAKVQDRSAKSVRNKLEARPHSLVTQSISSVSDLGE
IVDLAKPHGIKVVAVVMVPVEKNRQSAAVIGLDWSEYERNPADFVRQAARIADTVLLTSP
NSFGSGLELLNELK
>A0A7Y6EIR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas zeae|TrEMBL
MTNTILTRAEAALAHEEPLFADVGGDIAVSFEFFPPKTEKMDAQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTMDAAAHLTCVEATREEIDQVAQEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPDSADQQADIDNLK
RKIDAGANRAITQFFFSPEAYFRFRDAAAAAGIMAEIVPGILPVSNVAQTRKFAAMCGAR
IPDWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKGFHFYTLNRAELAYAISHLL
GVRGKKAEAVAAA
>A0A2N4S7R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dysgonamonadaceae bacterium|TrEMBL
MSVSELINSNSGKTAFSFELLPPLKGNSIRHVFTTIDRLKEFDPKYINITTHHSENIYKE
GDDGVIRKINIRKRPGTVAIAAAIQNKYGITAVPHLIAKGFTKEETEYALIDLSFLGVTD
LLLLRGDTNKLDIEQRKMDSHEHATDLQIQVNNFNKGIGYDGTRFEAPENPFSYGMACYP
EKHEESPNMESEIYYTKMKVDNGAEYLVTQMFFDNQKYFDFVDKCRAAGITVPIIPGIKP
IHLMSQLTVLPKVFRSDIPEDLARELRKCTTDDEAKEVGVEWCIAQCKELIRHGVPSIHF
YSLMATESVYRVAKKIY
>A0A6B8MQU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella oxytoca|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRTIAKDYWDSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A242M884|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia sordidicola|TrEMBL
MKPIELSFEFFPPKTLEGIEKLRATGAQLKTLNPKFVSVTFGAGGSTQQGTLDTVLEMMK
QGLEAAPHLSCIGSSKDSLRGILGGYREHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFNIEVAAYPEYHPQARSPKSDLDNFVRKVQAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPKWIARRLESFGDDKESIRAFGLDV
VTGLCERLVKEGAPGLHFYTLNGAAASKTIWERLKLQGR
>A0A2T1AJD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tritonibacter scottomollicae|TrEMBL
MTTPEISFEFFPPKNLEASFRLWDTVQSLAPLAPRFVSVTYGAGGTTRELTRDAVTTLHK
NSGLKVAAHLTCVSATRQETLDIADQYAEAGITDIVALRGDPPKEQGRFTPTKDGFGSSV
ELIEALAAKGKFNLRVGAYPESHPEAASQQANVEWLKRKLDAGADEALTQFFFEPESFFR
FRDACAKAGLDTDRITPGILPIENWKGVRRFAEACGTTIPAWLDEAFEKATRDDRCDLLA
TALCSELCTELLEGGVKKLHFYTLNRPELTRDVCHALGVTSKVRLENVA
>I0S9X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus anginosus subsp. whileyi CCUG 39159|TrEMBL
MSSQSPSISFEIFPPNPAVGNEKIMVALKEMQDLAPHFISVTASNNKFNIEETTVRLADF
IRNDLHIPTIAHLPAVYLTKEMVTETLTALDKVGVHKVLALRGDILPDVEPQKDFVYATD
LIEYIKKEAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYD
FQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSDTAHQIYQATHTFFDK
>A0A7W6BAC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium fabae|TrEMBL
MALKNEGRGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWDPDFVSVTYGAGGTTKAPTL
SAVTRFLSQTPLATASHLTCVGATKEETHHMIDTFRKVGVKHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGITIPVVPGIMPIQNLTQLKRFAGACGAVIPAFLDERFEGFDD
KPEERAKVAADVAAEQIEDLVRRGLDEFHLYTMNRAPLVSAVLDNLGFSRRAQKSAGAAA
>A0A0Q3VHF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus solani|TrEMBL
MSLLERMKNEILIADGAMGTLLYSYGTDCCFEELNISQAEQIQQIHKAYIHAGANLIQTN
SYAANYIKLQRYGLEDNVKEINTAAVRNARKAAGKDSYVVGTIGGIRGMKPNMVFLEEIK
RSFREQLYCLLLEGVDGILLETYYDIEELENVLQIVRKETELPIIAQVSLHEVGVLQDQT
PISKAIERLENLGADVVGLNCRLGPHHMLVTLEDIPLPSRAYLSAYPNASIPAYTDGKFH
YEGDPNYFRQSAKAFRNQGVRLIGGCCGTTPDHIQAFASELKGLPPISEKLIKKREQIRI
SDGNIPVREYTPLEEIVKMRSSVIVELDPPKHLNTAKFFEGVKAFKEIGIDAITLADNSL
ATPRICNSALGYRVKKEMGMRPLVHITCRDRNIIGLQSHLMGLHTLGLYDVLALTGDPAR
VGDFPGASSVYDLSSFELIQMIKQFNEGISVSGKHLQEQSVFSVGAAFNPNVRSIEKAVQ
RLEKKITYGADYFVSQPVFSLEKLLEIHGAVKHLKKPIYIGIMPLTGSKNTEFLHNEVPG
IKISEEIRSRMANLKDDPVHAAREGVAIAKSLIDAACELFNGIYLITPFMRFDLTAELAL
YAHEVSAKITRRNKNAKISIN
>A0A838VQW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostocaceae cyanobacterium|TrEMBL
MLNMHPRPLTTFRRAVQTGEFLVTAEVAPPKGCDPVHMLKMAQSLQGKVHAVNITDGSRA
VMRMSSVAASLILQQNGIEAICQVACRDRNRIGLQADLIGAHALGIQNILALTGDPVKVG
EHPDAKRVFDLESVRLLQMIQKLNQGMDCNGTILADGATDLFVGAAIDP
>A0A7W9FLQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecomicrobium pneumaticum|TrEMBL
MSVTLAKDGVRRSRLDGGPKGLAVSFEFFPPKTEAMEETLWRSIERLAPLSPAFVSVTYG
AGGTTRERTHQTVARILRETALAPAAHLTCVAATRAEIDSVVDSYAEVGVRHVVALRGDP
VTGLGTRFEPHPEGYDSAAALVAAIKRRHPAMEVSVSAYPERHPESADWTIELDNLKRKV
DAGADRAITQFFFDNDLFLRFLDRVDAAGIALPIVPGVVPVQNFSQTARFAEKAGASMPR
WLADRFEGLEEDAATRQLVAAAVCAEQVLDLVDRGAREFHFYTMNRADLVYAVCHLLGMR
PGGKPQGVEAAA
>Q8FNS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)|TrEMBL
MVMCCAQRESFPKIVVAAVAGAGGMKTGARSLPDHLHNIRYPGMSSTNISASSQWSISEV
LKRPVPGRVPFSVEFMPPRDDAAENRLYRAAEVFHDLGASFVSVTYGAGGSTRERTARVA
RRLSRQPLTTLVHLTLVDHTIAELQEILRGYAELGLTNLLALRGDPPGDPLGEWATSEGG
MSYALELIEMIKNSPEFSHFDIGIASFPEGHYRAGSLENDTRYTLAKLRAGAEYSITQMF
FDVEDFLRLRDRLVAADPIHGAKPIIPGLMPITSLRSVRRQVELSGSTLPRALEEKLLRA
ANGDEEANRNEIRKVGIETTSEMAERLIAEGVPDLHFMTLNFTRATQEVLHNLGMAPAWG
AEHGHDAVR
>A0A096LMU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. 4_8_47FAA|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRSHADIAAKIDEYRTTGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRKLADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A388PRD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MSRSQLIQALRAPARPTVSVEFFPPKTPEAGAKMLEVARALRPLGIDFASLTYGAGGTSR
DTTLAYGAELVKLGFPLIGHLTCVGHSRAELTEVIAGYDAAGFSGILALRGDPPKGQTAF
TAHPEGFAHAEGLVRHIAAVRPGRFAVGVAGFPERHPDATDDLSDTRFLAGKVSAGADFV
TTQLFLDNEDYFRFVARARAAGVTVPILPGIMPVLSLKQARNFCGFCKARIPEALVRELE
ACGDDEEAQRKVGVSWAVRQVRGLVARGAPGYHVYILNRAESALEMIGQLKG
>A0A0J5QHC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceibacterium sp. IMCC21224|TrEMBL
MALLNFRKRDAAPQGVNGQVEALLDGYSIEVMPRTAEKIECFADLLPTGTRVYIAHIDGT
PIEDMVATAKRLNAEGYPVMPHFPARIIKDKATLGDWIARYQGEADVRQALLLAGGVSEP
HGDFDSSMQLMETGLFDKAGFTRLHVAGHPEGNRDIDPKGGDAAVMDALRWKQAFSERTD
AQMALATQFAFDADPIIAWADALRDAGITLPIHIGIAGPAKLQTLIKFAIACGVGPSLKV
LQKRAMDVTKLLLPYEPTEVLTKLAAHKANHPDFGVTNVHFFPLGGIKTNAEWAIANGGT
SGTPASQQA
>A0A249KG75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Planktophila sulfonica|TrEMBL
MRSVKSGLTYSFEFFPPKDVEGEERLWAAMSQLESIAPDFISVTYGAGGSTRDRTIRITS
EITARTHIPTVAHLTCVGSTRDELVDILSKYRDAGIKSILALRGDPTGGPRAPWSATEGG
LNHADELVTLAAEFGGFTIGVAAFPDGHPSSEGDIDKDVQVLLEKEKRGATFATTQFFFD
TAKWKILVDKLAAKGSTLPIIPGILPVTNVKQLNRMAELSGVPIPSEISSAFAKVESNPD
DVRKVGVELATKLCQELLEAGAPGLHFYTMNTSSATREIYSQIKDER
>A0A2D8I2A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MDLGTSISEFFGRKKTIFSLEFFPPKNETGGEKMLNTAKLLKPYKPDFVSITYGAGGGTR
KTTLHYARILKQEFGFEVMPHLTCVGHTVKELLEILDEFSNEGFCNIMALRGDPPKGETS
FKPITGGLTYASELVSLIRKHYPHFGIGVAGYPEKHPESLDKKSDLTHLKHKVDAGADFI
TTQLFFENEAYFRFANECKKEKISVPILPGLLPVLSHGQVQRFCKMCEASLPNELESKLL
EVDEKSQPTVGTQWTNEQVKELLQKGSPGFHLYALNQATASLEILRGLGN
>A0A7K5VEH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Platysteira castanea|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7L2C9K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alaudala cheleensis|TrEMBL
MVNETQQPCSASSSSRSDGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRQLLDSGMVHGLHFYTLNREVATTEVLKRLGIWREDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLERVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A1Q7B7K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon 13_2_20CM_2_52_21|TrEMBL
MKGRVDAITIPALRNGEGDPSYPAGFRVTPQTRSLASAVIVRKTGAEAVPSLTCRDFRRS
DLDLVPSLFKKGLDNFLVVFGDPYPGYQIEDYDFRKTEDLIRGVLSVFDGQRPCIGAVTN
QYAKDQEREISRTLRKVDAGADYVVTNTAFDDRLVLDHADRLRSQGLKAPIFVQVSIPSG
LKNLLFVSRKFGIPVPEEVRQTLSRNPFGGGIQIAARAYTALRNEVSGIHFSYLHRSHNP
IPAYTHLLDAIETDGKLTVSIQAALRH
>A0A3E2H4I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scytalidium lignicola|TrEMBL
MHIKDIVAEAERSGQPTFSFEFFPPKTAQGVQNLYDRMDRMQGLGPSFIDITWGAGGRLV
QLTCEMVNVAQSQYGLETCMHLTCTDMGREKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVKYIRETYGYHFDIGVAGYPEGCDDQDDPELLIEHLKEKVDAGASF
IVTQMFYDVDNFVDWVSKVRAKGIDVPIIPGIMPISTYASFLRRCNHMNCRIPPKWSAAL
EAVKNDDAAVRNIGKGLVAEMCRRILDAGIHHLHFYTMNLAQATRMVLEELKLTPSTERP
LKQPLPWRQSLGLGRRDEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNRALWGEPKSIKDIAEIFVKYLENNLDSLPWSEVPITSEADIIKPDLIN
INRRGLLTINSQPAVDGVKSSHPIYGWGPTNGYVYQKAYLELLVPPGLMDELIKRIEHDP
DLTYYAVDKSGDLRTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGVDW
AHCYPSQSPSRQLIEHLMETWYLVNIVHNDFHQGHALFSLFDGLTVEGFDKPFDTVNHTN
GTTKENGTTMETNP
>A0A4Y8XX79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 4R-3d|TrEMBL
MALGAASIRTDHARTVRDLLATGKLSYSFEFWAPKTEKGERNLWNALRRIEAVAPNFVSV
TYGAGGSTRAGTVKATERIAADTTLVPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPRGEWVKHPEGVEYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWESDIRHFVA
KCRAGADYAITQMFFDPEDYLRLRDKVSAAGCDTPIIPEIMPITNVRQLERFSQLSNAVV
PPALKERILSVKDDPAAVRSIGIEYATEFCATLRAEGVPGLHFITLNNSTATLEIYENLG
LHEQS
>A0A2E8U430|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetovibrio sp|TrEMBL
MANIAEKSDFQSPRQNVIDFLADFTAETTPFSAAKVDDFREILRPGTTMFITFLPGSDFE
DTIAIAARLKKEGLNPVPHLAARSIPDAAFLDEGLRRLRGEADIDEVLTIAGAVDQPLGA
FSDSMQVLETGLLDKHGIKRIGVAGHPEGSPDMPDEAIAAALTWKNDFANRSGADVYIVT
QFCFEAEPIIAWDKAIRAAGNALPIRIGVPGLATIKTLLNYAKACGIGNSMMFLKKQAR
>A0A1D2SHL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lautropia sp. SCN 69-89|TrEMBL
MTNPSDPALSFEFFPPNTPDGAARLREVRARLAAFAPEFFSVTYGAGGATREKTLATVLE
IAAEGRTVAPHLSCVGATRESVRELLTLYRTHGIRRLVALRGDVPSGMREPGDFRHASDL
VAFVRAETAGWFRLEVAAYPEMHPQARSPRDDLEAFAIKVRAGADSAITQYFFNADAYLR
FRDDARRLGVDVPIVPGIMPIGNFTQLARFSDACGAEIPRWLRLRLASFGDDIEAIRDFG
AEVVAAMCRRLLAEGVPGLHFYTLNQSAATARVLEAIGLARG
>A0A0M7BBH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jannaschia seosinensis|TrEMBL
MSVRPAVSFEFFPPKSLEGSFRLWDCISALAPLAPEWVSVTYGAGGTTRELTRDAVAALG
ERFGLRVAGHLTCVDASREETLAVARGFREKGVTDIVALRGDPPKGSSGFEPHPDGFRDS
VELVGALAADGFNVRVGAYPDRHPEAADAEADVQWLKRKIDAGATEAVTQFFFDPETFLR
FRDRCVAAGIDAPIVPGILPIENWTKASRFAKACGALIPPEMAAAFDRAERDGRADLLAV
VQAAELADRLVEEGCEHLHFYTLNRPELTRDVCAALGIAPERALSRVA
>A0A2E3L125|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetovibrio sp|TrEMBL
MVAEKSDLIDPQQNIIDFLADFTAETTPFSAAKVDDFREILRPGTTVFITFLPGSDFEDT
ISIAARLKKEGLNPVPHLAARSIPDAAFLDEGLRRLRGEADIDEVLTIAGAVDQPLGAFS
DSMQVLETGLLDKHGIKRVGVAGHPEGSPDMPDEAIAAALTWKNDFANRSGADVYIVTQF
CFEAEPIIAWDKAIRAAGNALPIRIGVPGLATIKTLLNYAKACGIGNSMMFLKKQARNVA
KLMNVSAPDKLLVDLANYKATDPDCGLIGCHMYPLGGVKKTAKWTYAVVDGEFSMNPKGD
GFSLTMEI
>A0A3B9W4P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp|TrEMBL
MFPTRIEIIPSTGIIDQVQALVPLTTTLTMTCLPHHGIERTMRTSVELSTLGYTVIPHLA
ARSINDRAELTRIMRECDVAGIGEVFVIGGDRKQPAGPYGSALPLLEDIAQYTGGRMRAG
VAGYPEGHPTVAALDLLDALQDKQHLATHVVTQMCFDAPKILDYAALLRREGVDLPVWAG
VAGSVPRTKLVALATQIGVGSSLKFLTRKGPLARKLLSGDRYSPHALVAGLESQPGIAGI
HLYSFNNLDAVPDEVGPASSPTALQPALIRGAAREH
>A0A1N5WWC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cuniculiplasma divulgatum|TrEMBL
MQISNFQSKQKILKSVEIVPKRNENIDDLLAAREIFSDIADMVTAPENQMGRPGIDPLMA
LYIMTHGTNVIAMPHVTPRDKNTLYISSQILTSEKLGINHFFVIGGDPISGNFGREVREM
DTNETIRHIRKFSREQERDKEAIIGAALNPYRNSEEEIVRSKIESGATLFISQMCYNSEP
FKKKWIRQRKFKLFLGFMPILKKSNIESLSKMGVLLPEGLKSIIANSENLRDTSLKLIDN
LVSDMKGYIDGVHIMPIGNNEIAKEIMEVL
>U1QHX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halorubrum sp. J07HR59|TrEMBL
MPFDSMEGQLDHLPDGATVAITASPSLGLDATVDWSVQAAEQGYEVVPHVAARYVEDDEH
LDEVLSRLAEAGVTDVFIPGGDREEAIGEFESSHDLLTAMDRLGHEFDDVGITGYPEGHD
FISDETLAEVMDKKAPYATYVTTQLCYDPETILRWIETIRDRGIDLPVEIGIPGVMKYQK
LLKISRKVGVGDSIRFLQKTSGITGFIKQFIRSRGKFSPDELVDELDPYYQDAEYNLRGL
HVYSFNQVPDTETWREDRLNN
>R5LKC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio crossotus CAG:259|TrEMBL
MKIIDLLKSDKVTVSFEVFPPKSEANYESIYNAAMNVAALKPAYMSVTYGAGGSTSKSTL
DIAGDIQKRYDVCTIAHLTCAGADKDDIHRSLDGMKTKGIENILALRGDRPKDYDGDPFA
HYRYASELISEIKEYAGDSFCIGGACYPEGHVDAANKKEDIGNLKKKIEAGCEFLTTQMF
FDNNIYYNFLYRIREQGIVVPVVPGIMPITRATQVANALKLSGSNMPERFRNLVDHFGTN
PAAMQQAGIAYATDQIIDLIANGINHIHVYSMNKPEVAAGIQKNLSEIIK
>A0A3D9SUV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomonospora umbrina|TrEMBL
MRPVMPDRAPTIRELLAVGEKSFSFEFFPPKTDKGMQSLWRTIRHLEALRPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVNHSTAELRHLIGRFAGVGVRNILALRGDPP
GDPMGEWVKHPQGVEYAGELVRMIRSYGDFCVGVAAFPYKHPRSAGIEDDTRHFVAKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDIPIIPGIMPVTKISTIERSEQLSGAPFPPEV
AARFEAVADDPEAVRRLGVEHAAELCQELLDQDAPGIHFITFNQSPATREVYGLLNVEPR
SASLTV
>K9SK20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudanabaena sp. PCC 7367|TrEMBL
MANPSNQSDQVKSTTSLLGQAIADRKFLVTAEVAPPKGSDPFHMLEQARQLKGRVHAINL
TDSSRAVMAMSPLAASVLVQQQTGIEAVYQLACRDRNRIALQGDLLGASALGLCNILALT
GDPVKSGDHKDAKSVFDLESVRLLKLIAKLNQGIDINEKQLANGGTNLLAGAAVDPQLGS
WSGLVRRFERKLEAGAQFFQSQLITDFDRLDKFMHEVGNASGKPILAGIFLLKSAKNARF
INKYVPGVNIPDSIIDRLAQAEQPLQEGIAIAAEQVKMAKDICQGVHLMAIKTEHLIPQI
LDLAGVEPIAQD
>A0A501PCS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emcibacter nanhaiensis|TrEMBL
MAVTTMTTQETALSKFLTGYTAEVTSGDSKSIKAAGEKMAPGSEVFVASLPKNTLDDLVG
AITKLSESGLNAVPHIVARNIENYETLDNLLGRLVREAGVDRALVLGGDRDEAVGDYSSS
LELIETGLFEKHGIRKIYIGSYPEGHARIPDDILEQAIKDKLAAAEKAGLEVELVTQFCF
DAQPFIDMTRRFRAQGITTPLRVGVAGPAKTLTLIKYAMACGVGPSLRALKERENMAKSM
LSGETPEALLNELAQANADDPSLGLSGVHFFTFGSLIKSADFAGQHMAG
>A0A2R8BUC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Palleronia abyssalis|TrEMBL
MTRISYEFFPPKTLEASFRLWDTINVLAPTAPDFVSVTYGAGGTTRKLTHEAVTTISKST
GLRVAAHLTCVDASKAETLEIAESYAAAGITDIVALRGDMPGGCAFAPHSEGFASSVELI
EALAATGKFTLRVGAYPDRHPEAASDNADVEFLKRKIDAGATEAITQFFFEAETFLRFRD
RCDKAGITAPIVPGILPIENWKGVRKFAASCGTVIPDWVDQAFEAADRDDRSDLLATAIC
TEMSSELLAEGVDKLHFYTLNKPHLTRDVIHALGLAPEPGLEKVA
>A0A1G7PFT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces jietaisiensis|TrEMBL
MLAAGKTVSSFEFWAPKTEKGERNLWNALRRVEAVAPDFVSVTYGAGGSTRSGTVRATER
IVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMAEWVAHPEGL
TYAAELVHLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVDKCRAGADYAITQMFFEPE
AYLRLRDRVAAAHCETPVIPEVMPVTSVKMLERLPQLSNAVFPGELKDRILAAQRDPAAV
RSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLGLHHTRQA
>A0A560MBU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. ERR 942|TrEMBL
MSSRSESHNAGIRISFEFFPPKSEEAEQQLWNTVDELSDWDVEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLATGVRRFVALRGDPPGGVGAAYQP
HPGGYANAAELVQALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRAAGIKIPVVPGIMPIQNLTQLKRFAGACGTNIPTWLDERFDGLDE
DVEERAKVAADVAAEQIQDLVRRGIHEFHLYTMNRSALVSAVLERLGLERKVDARAGAAA
>A0A2K9CEZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 02C 26|TrEMBL
MSEERRYSFEFFPTKTEAGHEKLMAVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLE
HEVKVAAAPHLSCVGDSKADLRGLLSEYQAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQAQNFEADLSNFVRKVKAGADSAITQYFFNADSYFY
FVERVQKMGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSASIQAFG
EEVISNMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1Y4M9C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoflavonifractor sp. An176|TrEMBL
MKIAELFGQGRPVFSCEIFPPKRDSPIDSIYRTLDGLKDIRPDFISVTYGAGGGGNVNHS
TQEIACMIENEYHITAMAHLTCVGCTKESALEVMNTLKAGGVENILALRGDHNPNAVSHT
DFLHADDLVSWIRQHGDFGISGACYPEGHPESPDVVSDIRYLKQKVDAGVTHLVSQLFFD
NDDFLRFWERCRLAGIEVPIEAGIMPVLSKASIQRMVSMCGASLPRKLTRILARYGDHPQ
AMREAGIAYAIDQISDLIAAGVDGIHLYTMNNPQVARQISDSITAIRSV
>A0A3B9QQ60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Acetothermia bacterium|TrEMBL
MRLDRLFEAGKFVVTVEVEPPKGTRVSEMLERAESLRGLVDAINVTDQQSSVMRLGSLAS
CHLLKERGIEPVFQLTCRDRNRIALQSDLLSAWALGIENVLCLTGDHVSLGDHPQAKPVF
DLDSVSLLWTARRLKEGYDLAGNPLQGSPDFCLGAVVTPEADPLEPQILKMERKIRAGAQ
FFQTQAVYDPKAYERFTREIEGLKAPILVGIIPLKSAKMARFMNENIAGIKVPDGVIAEM
ERAKTREERRRKSAEICARIVQAVRPHCQGIHLMPMGWEDLVPEILELAGINP
>A0A7V4N160|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSLRSDLESGKFAITAEIGPGKGTDVTEIAEVAEILRGRVTAANVTDQQSSVMRLGSLAT
CHLLTDHHLEPILQMTCRDRNRIALQSDLLSAWVLGVQNVLALTGDLPHLGDHKDAIGVY
DLDSVQLLSVISRLNEGYDMMGNELNGKPDFYAGAVVNPGADTEASFDMQLRKMEKKIKA
GAKFFQTQAVYEPEKFERFMKRVEGFGVPVMAGVIPLKSVGMARYMNKNVSGVFVPEETI
QRLAAAEDKTQAGIDLCAELIRDLKDLCQGIHIMPIGWEKRVPEILDKAGL
>A0A7G7CM22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium incognita|TrEMBL
MAPRISASAPLDELPQPAPQQQRVGLSFEVMPPRQDHPDELLSVLESYGPDYVAVTSSRR
SGWLEGTANFISEISASSSMRPLAHLACSAGSEAELRHWTERLIDAGVRGFLALRGDLVP
QPGYLQHADALVRLIRQVEGEQVSRLAAGRLAVAVACYPNGHEESKTPSEDFEVLLAKQR
LGADLALSQLFFEAEDFLRFRARADLFGIRIPLVPGVMPITSLRRLQRMSELTGLAVPRD
VGKRMEAVEGTAREYDVGLELTAQLVRRLVRSGVTGIHLYTFNNPQVVQDVLQRVDI
>A0A7W3JRA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium halimionae|TrEMBL
MVFGPCGGVREDAQCEAQDARCGFIDAPTPLWSPSALAAGHPDGLRDLRADTGGQHAGAI
RFAERLRSEWVVTADLMLRATDSSVVADTSARLASVLSAAVLGELATAGPTLAPAHRAAL
IQASGLNVISALTCRDRNRVALEGELAALADVQVAAVLALTGDYPTRRDKDTSAAVFDLD
STRLAALAHRGGHLVAVAEQPAAHPVARRAERLRQKLNAGAEMCLVNMCGGADAVARFRE
DLEMIGAEIPLIPVIPVVLSAAAADGLSTLPGTVVEPSLREQLSRASQPEQVGIKYAVSL
AHELAAISGVAGVHLSVFGMSDDPTGVRASLLLADIAHRIRMEGR
>A0A7X5WSV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTAIRDMLQRGPTLSFEFFPPRTLAAEQRLRETIDTLEKIEPDFVSVTYGAGGTTRETTR
DTVIEMCAARGFEAMPHLTCVGHSYAEIHDLIDDYEAHGVGNILALAGDXAHGVGNILAL
AGDPPADGSPNPGDFRYALELVETVRERSDLCIGVAAFPEVHPRSVSRVMDRLHLAEKLN
AADFGITQFFFDAAHYFSMVDELAALGCEVPVVPGVIPVVNPAAVRRFAAINGSAVDEAL
FARVEAAAPDSDDRLEIAVDAAVSLIDELXVIDELVAGGAPGVHLYTLNQTAPVVRICER
AGLSRAQAS
>A0A6I2V4G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVVRTSYSLEFFPPKDGEGETRLWDALENLQSINPTFVSVTYGAGGSTRNRTIGVTEEVT
HRTKIPTVAHLTCVGSSRQELISILHMYKAAGIKGILALRGDPVGGPRAPWTPTSDGFTH
ADELVQLIHEFGGFDIGVAAFPDGHPGSDGDSKKDIDVLLRKEFLGAQFATTQFFFEVSQ
YVKLVDALQARGSTMPIIPGILPITNVKQLQRMAELGGTPIPPQVAKSFGAVEHDPRAVH
QLGIELASQLCEDLLSAGAPSLHFYTMNSPTATLEIYGNLNSAD
>Q63PT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei (strain K96243)|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A7X5WV50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAFLREFLDVTAGDIDLVGVASYPDGHAFISEAGLRQALLDKQELFAEAGVAGHAATQIC
FSADTVRRWLRQQRAEGFELPVHLGVPGVVDRAKLLAMGMRLGVGXRLQPGRPHRTARPR
LRTARDRSAARLHLQPGRGHPGLAGADRRPRCRLRHRPRGLGYGQGP
>A0A7U4GIW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia enterocolitica LC20|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWNSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDDDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A7C5DVZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MSWLQKVLEEGNFAVTCEIGPPKSSDFSVVTKKCDWVRNFVDAVNVTDNQTAIVRMSSFA
SCLIASRQNVEPIMQMVCRDRNRIALQSDFLGACALGIENFLCLSGDHQSMGNHPQAKNV
FDVDSIQLLQILKNMRDEKVFQNGEPVKGEIKAFLGAGANPFADPLELRVLRLAKKIEAG
AQFIQTQAVFDLERFARWMEEVREWGLHRKAFIMAGVIPVKSVRALEYMKEEVPGLEIPD
YFLERMRKAKDPKEEGIQICTEIINEVQKIKGVSGVHI
>A0A7K1C967|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARIADLIAKGRTFSFEFFPPKTDSAQLSLGRAIGELESLGPSFVSVTYGAGGSTRQRTH
AVVSWMRKETTLTPMAHLTCQGHVRSEIRDILNAYADDGVQNILALGGDVPTDGEPAPSD
YTYASELLDDVSGDGRFSVGVAAHPEVHPRSTDRASDRRFLAAKLSRADFAITQFFFEVE
VYVRMMNELADLGVNKPVLPGIMPVTNKKQIVRMAEMSGAAMPQWLIDRLDKVDDPEDVR
RVGVEAATELCRDLLDAGAPGLHFYTMNRSTATREIHANLGLSSAC
>A0A7K0NG31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRRPFSFDTPNGKPIFSLEFFPPKDEKGEANLWVELAELNSLQPEFVSVTYGAGGSTRER
TVRITSEITARTGLRTVAHLTCIGSSKNELSEILDQYWQAGIRDILALRGDPPTGPQSEW
IPTAGGFSHSDELVSLAAAANFNVGVAAFPDCHPASNGDHLKDISVLLEKERRGAQFATT
QFFFSTDKYYNLVNELKEQGSNLPIFAGILPITQVKQLNRMAQLGGTPIPANIVQKFSRI
EDDPEKVKALGIEIAVNLCEELIAMGAPGLHFYTMNNAYATKEIVKRIGLR
>A0A7V9CW06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPGGLVELLRRPRYEVFPLPGIEDELAEHVPTDVKVTVTSSPKRGLEATLRLSADVARRG
FDVVPHVAARLVAGEAHLREIFDTLREIGVREIFVIAGDAEEPAGTFAGAADLLAAMDEL
GHPFDDIGISGYPESHPFIRDEATIQAMFDKAPFASYIVSQLCLDPGVIAWWIDAVRERG
VDLPIHVGIPGVTPRRKLLRIATRIGVGESVRFVRTQGNVIARLLLGGSVGPHYLLDGLA
PQVGRIAGFHVYTFNELGETERWRQAMLERLADSATA
>A0A3D5DIF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTAFTDLLGQRLLMCDGAMGTMLHAAGCALDRALPEVNLSDPKLVAAIHESYVSAGADII
QTNTFGANRLWLAEHGYPDQVEEINRAAVAIAREMSERSNRVVFVAGSVSPAVTARQRRQ
VGAAERKDVIAEQILALTAEGVDLLILETFGYLDELAEAVQVAAGICGTPIVAQATFADD
GRTLGGETPHEVASVLGELPAAMLGTNCTTGPQRMLAVVESLVRYSALPVSAQPNAGQPR
KVGHRRFEFSIDATYFARYLRRFAEAGAAMVGGCCGTTPTHIEAAVASVAGLPPAGIRAG
TQPRSRRPARGQAGQPGDATGILAARLAARDFVVAAEIPAADGGAVSQTPGTVTALRGRG
VELFAVTAPEDPRAHRDSLGTALFLQAHGGVETIVTMTTWDKTIMTLQADLLGAHALGIR
SIICETGNPPVLGDYPAVDGIWEVDSLGLVALLAGLNAGRDLDGLPLTTNTSFCIGTRVN
PGAQDTAAEIDRARAEVAAGAQFLVTRPVYELASLRQMVGALAGTGVPVLLSVAPLGSFE
DADYLAHEVPEVSIPAATLRAMERAGKTAERATGLALAADLLREARPLVDGVMLTLAGGD
PAGLDPLLAALR
>A0A7K0UX21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKKIGEGVTYSFEFFPPKDPEGEERLWSAMGALEPIAPDFISVTYGAGGTTRDRTIRITS
EITQRTHIPTVAHLTCVGSTRDELIEILGRYKQAGIHNILALRGDPTGGPRAPWTPTPGG
LNHADELVTLAAEVGGFTIGVAAFPDGHPASGLDFAEDIEVLLRKEEAGASFATTQFFFE
ADKWKALVDRLAARGSKLPIIAGILPVSNVNQLNRMAELSGVPIPTSIADRFAALKESPE
DVKKLGVELATQLCEDLLTAGVPGLHFYTMNTSSATREIFEQIKDKKRG
>A0A4Q1T025|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ammoniphilus sp. CFH 90114|TrEMBL
MREKSGLRELLQNRVLIADGAMGTLLHRYGIPVGTCGEELNVTRPDVVRDIHLQYVLAGS
ELIETNTYGANREKLSKYGLEDQVEELNRAGVGLAREAAGDLAFVVGSVGGILGGRRRNI
PSEELKEVYAEQIKSLVEAGVDGLLLETFCFVDEAIIALSVARRFSSLPIICQLTIQDIQ
RTQDGYSLESAFGRLVDAGADIVGLNCYNGPANIIRSLESLPVKEGLQLSVYPNAGLPEY
VDGQFLYPSSAEYFADSAEKLHQLGARIIGGCCGTTPEHIKAVASRLKGRTPIYKKESAV
KEITNEPKVIISSEVFQEKTIPELVKEQPTVIVELDPPRDLDFQPFLEGAASLKEAGADA
ITMADNSLAMTRMSNMALGALVKEKVGIRPLVHITCRDRNSIGQQSHLMGLYALGIDHVL
AITGDPTRYGDLPGASSVYDMTSFELIRMTKQLNEGVGFSGRTLKKRAAFTVAAAFNPNT
RHLHKAVERLEKKVDAGADYVMSQPLYDHEQIFQVAEATRHVKVPIFIGIMPLTSHRNAE
FLHNEVPGIRLSDDVRARMARYEGEDAKKQGVEIALELIDTARQYFNGIYLITPFMRYEM
TAELTKYVKNS
>A0A6L5ZLW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSPIRTAPSLGAVLAGGGHSFSFELFPPKTDAGEQALWQTVRELEALKPTFVSVTYGAGG
STQDRTVRITKQIAEHTTLLPVAHLTCVDASVDDLRRVIAQYSDAGVNTIMALRGDPIAG
PESRWVQHPGGLQHADELVALVRSLGAFSVGVAAFPEGHPESGDFEEDARVLAAKQDAGA
EFAITQFFFRAEDYERLVTRAAAHGCTMPIVPGLMPVTNVAQIERFAVLSGAQFPSELAD
KFGKIKDDQSAVHELGVEVAADLGGKLLAMGAPGLHFYTLNRSTSTREVYEALGLNEV
>A0A852F6Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peucedramus taeniatus|TrEMBL
MVNETQHSCNASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRHEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDELEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A2M7JJ47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_8_14_3_um_filter_51_11|TrEMBL
MPLKEKIEAGGFAVLAELEPPKGADFHSLLANADLVKGRVDAFMVPEMANSVVKASSLGG
CAFLQNRGFETVLQVCCRDRNRLALQADILAAGAIGIKTVMVVQGDDITFGDHHQARAVN
DVTLMQLLEAIAGLKNGKDMAGIELKGAPDFFVGSTFNAGAAGGALDLEIEELKKKKGLG
AAFVVTTPVFDTDIFEKLLVKLKPVGVSVIPTVLLLKSAGMARYIDRNVKNIFIPSQLIE
SIQKAPDKPVECVSIAGKLISRFKEMGAPGVLVSTIGWEEKLPQVLDEARL
>A0A537Z9R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAAPGDLVVGEPGHRPGSPRSGRLARRWRGGPRAVSGLPARSHLHRLLASGQFVVTAELQ
ATDSPDPESVYRLADLLRGSVDAVNCTDNSAAHPHISPLAAGHLLLDRGVEPIVQLACRD
RNRLALQADLVGAVALGARNVCLMTGDDVTAGDHPEAKPIYDIDAVHAIQIARIMRDRGI
YVSGRRLDRPLPLFIGAVENPFAPPHDFRPMRLGKKVEAGAEFVQTQIVFNLATMRVFMA
RSGELGLLDRVFILPSVYVCRSAGAARYLRDMVPGIDVPDSVIARIEGVPSERQADEGIR
IALEIVEELREMRGVAGVHLISIKGDESIVRLVEEAGLLPRPAGFSVNGGLHGAE
>A0A2M7JJ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_8_14_3_um_filter_51_11|TrEMBL
MNQTRAVKTDSKLEKILAAGHLAVTSECGPPRGSDSDLIKKKAELIKNHVDAINITDNQT
SVTRLCSLASCIHLKLMGLEPVLQMVVRDRNRIAIQSDVLGAASFDIRNMLCLSGDHQRF
GDSSQGQNVFDLDSMQLIQTVRRMRDEGKFLGGDEIKRPPKLFVGAAANPFADPFEIRVR
RLAKKAAAGAEFIQTQCIYNLDRFEEWMKQVRDRGLHEKVYILAGLTPLKSAGMAKYMKN
RVPGMDVPDDVVKRMSGVPKEKQPEEGIKICVESVQRLKELEGVAGFHIMAIEWEEKVPE
IVEMGGLYPRPNPDAI
>A0A350MUU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKSGSNLERLLQEGKFVVTAELGPPKSADADVIRKKANILKDVADAVNITDCQTAIVRVS
SIAAGCILVQMGLEPIIQMTCRDRNRIAIQSDLLGAAALGIRNLLCLTGDHQKFGNHPSS
KNVFDLDSIQLLKMVKDMRDEKKFQCGEEMDIEPRFFIGAVENPFADPFEYRALRLAKKV
AAGADFIQTQIVYNVDKFSQWMERVRQLGLDHKVYILAGVSPLKSVGMAKYMKHHVPGLD
VPDALIERIGKAENPKEEGIKICVEIINRVRKIQGISGVHIMAIEWETSVPEIVERAGLL
PRPKIA
>A0A330HSD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium hawassense|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVIKEFADMGVKRFVALRGDPAAGVGT
IYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A4P5RH85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSQMREKLENTNEVVFTAEFPALDGGGMAKVEKNAARLAPWFVGVNATDNPAAHAHASNT
ASAIAMKMHGIEPIMQIVCRDKNRLAIQADMMGAALHGIDNISLLTGDDVTAGDEPESRR
VFDIDSTQAINIARIITTGKYLSGRKIDPAPNFYISAVENPAAPPFDYRIERALKKYRAG
AKYLQLQICYHSDRLEKFCAGVAKIAPDLKLIPTIVLVKSAKPMSFMHDKVPGIDIPQDI
LNRVSSAADQAEEAYKLTVELAKHAMTLPSVRGLHVTDFRHDDSLERFMYDLGQKPRN
>B8GBM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexus aggregans (strain MD-66 / DSM 9485)|TrEMBL
MHSTLQRRLAAGQTVVTGEIAPPKGAARAHLETLAQNLRTYVDAVNLTDNQRGIARMSSL
GGSVILHQLGIEPIMQMTCQHRNRIALQADALSASALGVRNLLAMTGDHPRIGDHPEAKN
VLDLNSFQLIRMLRTLRDQGTFQSGTPLKEAPRFFIGSVANPNVERAARLEKKIEAGAEF
VQTQLIFDVNRFRQWMADVRAAGLHQQAYILAGVMILRRPQSAIYLRDHLPGTLMPDVIV
ERMQRATDSEAEGIALAAELVTELLSIEGVAGVHLMSVDWTRAIPRVVERAGLLPRPPAP
EASADEA
>A0A4D6XVP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MNVFFEYHRDIINQKIENLRNTVKCSFEFFPPKNVIAEEKLWCSVKKLSKLKPNFFSITY
GANSGEREKTYNFVKKIHKTTGILTSAHLTCVDSTPVELKKIAKHYWDNNITSIVALRGD
TLEKHYKHKMYALDLVILLKKIANFDISVATYPELHPESQNMTCEIINLKKKVDAGANRA
ITQFFFNIHNYLYFRDNCIKNKINVEIIPGILPVLNFKQLKKFAAMTNVHIPKWMFELFN
GLDNDIMTEKIIGASIAIDMVKKLSSEGVKNFHFYTLNESDITYSICHLLGL
>A0A538EYY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSSRFEERLANGPAIVGDGGMGVLVTSAVPRLRCPEEANLKAPESVVTLHTSFIRAGADL
IETNTFGANRRKLAQLYLEDELERINGAGVKLAREAREVAGREVFIAGSIGPLGDAQGLS
PERRAAIFAEQAAILDGRGVDLFMIETFYELDELETAIAATRSVSGLPIVATLTFDEGAE
TLAGVTAAEAAERLRPLELAAIGANHGAGLHAALAALEAMGLDGAPLAALPNVGLASLSG
GRVIYPHATPEYFAEFAAHASRLGARLIGGCCGTTPVEIAAIRSAVEDAREPSAPLDVLE
RELPEPQLGAGPYETELARKFRESEWITCVELDPPKGGTYDAMLGVARTLKTAGVGFVDI
NDNPMARARANALMAAVAIERDCGIETIPHVTPRDTSIMGLESLLLGAHAEGVRNVLSVT
GDPPEIGDYPGSRGVYEVDSIGLSQIVTRLNHGEDYNGKGIDAPTSFYLGVAVNPSADDL
ETELERFRQKVEAGARFAMTQALFDLSYLDRFEEQLGGWPVPLLVGIFYVRSHQLAVRLH
NEVPGIVVPEHVQRRLESAGSNAGAEGLALARELYAEAREKAAGVYLIPPFKQPEAALDV
LA
>W3AUJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium JC7|TrEMBL
MRIIDILNSGKVTLSFEVFPPKKIENFESVQQATEDVAALHPSFMSVTYGAGGGTSEFTL
NIAKNIRDKHGVEVLPHLTCVSSTREHVHNMLRKFKENGFENIMALRGDIPKDGTPHDDY
HYASELIADIKAHGNFCIGGACYPEGHVECAHKDEDIKNLKLKVDAGVDFLTTQMFFDNA
EFFNFLYRLRENDIRVPVLAGIMPITNAKQLGRSVALSGTTVPTRFKEIVDKFGDHPEAM
KQAGIIYATEQIIDLIANDVKHIHVYSMNKPDVAEAIQKNLSEILKV
>W0P5J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola str. USDA|TrEMBL
MKNFFQYHKDIILQKKENISKDIKCSFEFFPPKNPIAEKKLCSSVEYLSKLNPVFFSVTY
GANSGEREKTYAIVKKINEKTGVITAPHLTCVDSTPDELKKIGEHYWNSGIRNIVALRGD
TLQKNYKHKMYALDLVILLKKIANFDISVAAYPELHPESKNATFDIINLKKKIDAGANRA
ITQFFFNIESYLYFRDNCIKNNITSDIIPGILPVYNFQQLQRFSSMTNVKIPKWMFEIFN
GLDDDPITQKMIGSTIMIDMIKNLSSEGVKNFHFYTLNQSDIIYSICRMLDL
>A0A3C1DJZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDLARRIAARGSEFLFFALTPPRTTVSSERAQQIADVTRRRLAGLQLDGLVLYDIDDESD
RNPQERPFPFLPTMDPATFRARHLKDWSTPVVVYRAVGKYEEDDLRSWLEAQGADDVLTV
FVGASSRHKKSSTSLVRAQELWAGTRPDLQLGGVAIPERHTRSGVEHLRLIAKQEVGCSF
FVTQVVYDVNAAKNLVSDYRYECAARGLPPVPIVFTFSVCGSLKTLAFLEWLGVDVPRWI
QNDLRHAD
>A0A4Y7SY97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprinellus micaceus|TrEMBL
MKLSEKISARGQSRPFYTFEFFPPRTNQGFENLVARISRLATLDPLAISVTWGAGGSTKD
RSLELAGITQSHPYNLDTILHLTCTNMQEGLIDDVLKSVKDKGIENLLALRGDPPRGKEE
WIPSDPRFTHAVDLVRYIRSVPEYSSHFCIGVAGYPDGHPDTSLDEEVEIANLKAKVDAG
ADFIITQLFYDVEQFIRWVKKVREAGITVPIIPGVMPIQTYATFARLTKLCGTTVPQDLE
EALKPLKHDDRLVKDFGVEYAIDMIQKIHAAGDIQGFHFCTLNLEKSVQRVLEGLRWTGV
SQGSPNKLIADLPAPLGESGLLITPTSAASTATSGLVSLTNKSKTEQGKGELNNAATWDD
FPNGRFGDFKSPAFGNQDPWGGSGIARSDVNPDWGNPKSCEDLTRMFTNYLESQIATTPF
SDGPLCPESVTILPQLKKLTERGWWTVGSQPAVDAVSSADPIFGWGPRSGWVFQKAFVEF
FCDKKDADAIEKYIADNGKGWVHYFMANDKGDLRGNVPGEGRNAVTWGIFPGSEIAQSTI
IERESFITWKEEAFSTWRGWASLYPPGSQERHVLETVANERWLVSIIHHDYREPDSLWTF
VFDKELGF
>A0A0K2ZZQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas translucens pv. arrhenatheri LMG 727|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKTYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQASDALSDLRHFKAKVEAGADGAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQALGDDGDAIREFGADLV
AALCQRLLAGGAPALHFYTLNLAKPTTSVLSRLE
>A0A538AH66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSAGSPSRLASLLRQGVFCVTAEVVPPRSADPSAVSAQARALVGYADAANVTDNPVASAH
MSPVAGAALVARAGIEPVIQLTTRDRNRLALTSDLLGGWALGARNVLCLTGDPPTAGDHP
DAKGVYDISVVELVRLAVRLRTEGRLLSGADVEEPPRYFVGVADAPLAPSSTLDRLEEKV
DAGAEFVQTQIVFDADAFEEWAGRARERGILERASVLAGVAVAGSARAARSMRDRLPGVV
VPDRTLALLEDAGDAAEDEGLRLAVEVVARLKAIEGIAGIHVMGLGRLDPVRKVIAGAGL
TPRPPVARRGAR
>A0A1B9RTD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. AC27/96|TrEMBL
MAHIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
SGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPHDFRPYRLAKKIEAGAQFVQSQYCYDVPMFRDYMNKVRDLGLDEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIAGVSGVH
VMAYRQEEYVAEMVHESGVLKGRQPWKHEANRTDALVAERLEHIRGGKEENQQEMAEAAA
HHPSHKTH
>A0A7Z1WMC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVK
TGKEFTPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A8I0FJU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. C1|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRIIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A8C7JNV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus kisutch|TrEMBL
MVSFGRVEAIFIISPGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTESGDHWFS
LEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCG
LESILHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKH
IRCEFDDYFDICVAGYPTGHPEADSYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVR
DCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIRNYGIEQ
TVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVED
VRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMW
GEELTSEQSVYKVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMMDELDKVNRRGVLT
INSQPTINGKPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPRVNYHIV
NVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYED
ESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPDEQPTDPAK
>A0A8C7HXC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus kisutch|TrEMBL
MQHNGARVEDTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIR
NYGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVN
RRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEQT
AEQPNDEQSDKEQPGK
>A0A2T0BE20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium vincentii|TrEMBL
MRVRNYIKTQPLIFDGAMGTYYAELDSAGKKCELSNLNNRELILEIHEKYLDAGCKAIKT
NTFGANKIYLESDFEKVKEVITKGYNIAVEAISEKDAFVFCDIGPISFVKNENLFEDYKD
IVDVFLSLGGGNFLFETFSSDEYLKDLAKYIKSKNKEAFILVEFAVSPDGFTRLGLSGKK
IFKELSNVEEIDAIGFNCVSGPQHLLDYIKNFDIEDKIVSIMPNAGYPTVVNNRTFFDNS
SDYFANQMLKIATQGVAILGGCCGTTPEYIRKTVQKLKTFTLDDILKAEVILKSESNESK
IENEFLIKINSGEKVIAVELDPPMNTDIDFFMKGAKILKSLGVDAITIADCPIARARVDS
SLLACKLKRELNITSIPHMTCRDRNINATKALLLGLNIEGVNNVLVVTGDPVPSAKKDEI
KTMFSFNSAVLAKHITTLNEEIFKNPFNICAALNVNAINFESELNQARKKIISGVSMFLT
QPILTKEALKNLKLAKETLDAKILGGIIPVVSYRNACFMNNEISGIKVSEEITELYKEVS
KEEATELAVKISVRITKEIAPYVDGYYIITPFKRIDIVERIIVEINKTKGYASNRK
>F7H2X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callithrix jacchus|TrEMBL
MVNEARGNGSLNPCLEGNASSGSESSKDSSRCSTPGLDPDRHERLREKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCHQRLEEITGHLHKAKQLGLKNILALRGDPTGDQWEEEEGGFNHAVDLVK
HIRSEFGDYFDICVAGYPKGHPDAESFEADVKHLKEKVSAGADFVITQLFFEADTFFHFV
KACTDIGITCPILPGIFPIQGYHSLRQLVKLSKLELPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCRELLASSLVPGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKNYYLFYLKSKSPREELLKM
WGEELPSEESVFEVFVHYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGVL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKAHPEEGGGDSVTLHPD
ALRWSHSCPTCLLYRAASLGNTSLHVSQHLASTPPPDERSW
>G2FRQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp. OT|TrEMBL
MENKFKESILDKNVLSVTWELVPGRGANEKAQQSAIASSEQAAKGGRVHALTITDNPGGN
PAMLADYLGVEILGMGIEPLVHFTCKDKNRNQMESQLYALDRAKVRNLLVMTGDYTYTGF
EGRPKPVFDLDPCNALKLISEMNKGLEIPGMKGPTYHAPSDFFAGAAFSPFKATEAELMV
QYYKLKKKIEGGAKFIVCQLGYDARKFHEVIQFLKVNKLDIPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNTEKTAADKGVGTRMLRAAKLYAILKGIGCAGVHIGGHNLKHEQ
VEYIIDEGEKLFPKWQELVKEFDYPQPNGFYYFEKDEKTGLNTDRPTNRAKLPLDAPVGM
GYSFMRKMHALAFTPNKKLFGMMRGIYISAEGKKRMKKLHFFEHMAKVAMLDCKDCGDCA
MLDLAYLCPMSQCPKNQRNGACGGSFNGWCEIYPNEKKCFWVRVYARLKSHGEERSLDVP
MVPPPNWDFYQTSSWANFYLGKDHSAPILGIKRPPSKVPASK
>A0A6H3STA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAIMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKYLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A7G9QFT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter roseus|TrEMBL
MKITDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QANGLLQKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHCYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMSTDFKYLKKKVEAGAEFIVTQMFFDNQKYFDFVKKCRENDINIPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNNEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKKIAKAIF
>R7Q356|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chondrus crispus|TrEMBL
MPASNGMEGATSTCFSDADPNLRHLPKIADKIQYRQLEGRPFFSFEYFPPKTEQGVSNLY
QRVERMTAAEPLFCDVTWGAGGSTSDLTLSLSGNIQKYLGVDVMMHLTCTNMPSGNVLEG
LEGAKALGIRNILALRGDPPAGKEWTKCEDGFEHGTDLVRFIRANYGDYFGICVAGYPEG
HPAGFLDGKMSFEDEMKHLKDKVDAGADFIITQMFYDVDCYLKFVRSCREQGITIPILPG
ILPIQNYMGFKRMTGFCKTKVPQAILDAIEQIKDNDVAVKQFGVRLGVDMCRRILKSGLS
PGIHFYTLNLEKSAMAIIDQLDLIPQTESIRSLPWRPATVDKRRNENVRPIFWANRPKSY
LDRTSTWDEYPNGRWGDNRSPAYGDLREYHLLGGGGWCSAAHRKDAAARYGELNDFEDVV
DVFTRFQKGELKRLPWSETEELASETLVISAPLVWLNKNGLLTINSQPRVNAAPSSDVTV
GWGSPGGYVYQKAYVEFFAKPQIVDALFEAAKDIPSLTIYAAKVKNDELRTNAKTKTTCA
VTWGVFPDREIVQPTVVDPQSFKAWKSEAFAVWENVWADLYPKDSPSRKVLKELHDTLYL
VNVVDNDYVGGDIFAVFKTVLASPTHASLFA
>A0A551ZDH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis sp. M_QC_C_20170808_M3Col|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDMAGIPPIHN
>A0A562QDR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas duriflava|TrEMBL
MTTIQPSVSFEFFPTKTEAGHEKLLNTARQLTDYAPEFFSCTYGAGGSTRDRTYNTVLQL
SNETRIPTAPHLSCVGDSKAELRALLEQYRSAGINRIVALRGDLPSGMGLSSGELRYANE
LVSFIREETGDHFHIEVAAYPETHPQARNFEADLANFVRKIKAGANGAITQYFFNADSYF
YFIERARKLGVEVPVIPGIMPITNYSSLARFSEACGAEIPRWIRKQLEAYADDVKSIQAF
GEEVVTTMCERLLAGGAPALHFYTLNQAEPSLAIWNNLGFKS
>A0A1D7YZD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium wasabiae CFBP 3304|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWQSGIRHIVALRGD
LPPEGGKPEMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSVFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPEVAR
>A0A2K4LU10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FW305-E2|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1G1NA03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium RIFCSPHIGHO2_02_FULL_48_11|TrEMBL
MTKITDIFEQKPHTFSFELFPPKTDEGYQKLLETIKALAGLKPDFISVTYGAGGGSRDKT
FDIVQHIQDKHKITGVAHLTCVLHNKNEIKNILADIKNRGIKNVLALRGDPPKENPDWQP
GKDNFRYSSELCAFIRKNFGEHFGIGVAGFPEGHLLCQDRDRDAQFLKIKIDNGADFVIT
QLFFDNKNYFDYVARLRKLGVKARVLPGIIPITDYQGLVRFCGLCGATVTAELKKIFEPI
QNDKEATLKAGIDFAVRQCQELLAGGAPGLHFYTLNKSTPVDTILNQVRR
>W8FD58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter swuensis DY53|TrEMBL
MKVTEHLTRANGKTLFSFEVLPPKKGENIQNLFSNIEPLLEFKPPFIDVTYHREEYVYRQ
HANGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFVPEPDGHAYACDLIGQVSDLNKGAYLDEEQDDVWATNFCIGTAGY
PEKHFESPNSGADIRYLKHKVDRGAEYIVTQMFFDNEQFFQFEQKCRAAGITVPIIPGLK
PLTTKAQLTALPRSFYLNLPDELVDAVHLAPDNAAAREIGIEWCINQSRELMAHGVPCLH
YYSMGKSESIRRVASALF
>A0A496PFJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Galactobacter caseinivorans|TrEMBL
MPHYPATPPSLSYEVYPPATPRAREALNTTLDALAATHPDFVSVTYSGTPERRRTTLELI
HQILDHTRLRPLAHLTCVGESADTLTDLVRHFISLGVRGVLAMRGDLPADPNGERGEYPF
ARYLIELIRRVEAQNAVALGAGRLSIGVAAYPVRHPESPSFQHDIEVLLGKQRSGADYAI
TQVYFRPEEYTGLVAAARTAGVSIPIVPGLLPVDDVRRLERLSAMTGVAPDPLLAAALEA
ARTESERTRIGVDFAASLARRALEDGAPGVHVYTFNKHRGATELVERLELPRRRADARLD
SAARVGA
>A0A2Y9TZ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnobaculum parvum|TrEMBL
MSFFHANQREALNQSLAEINGQINVSFEFFPPSNVEMEQTLWQSIDRLKNLKPKFVSVTY
GANSGERDRTHSIIKGIKDKTGLDAAPHLTCIDATPEQLREIAKDYWDNGIRSIVALRGD
LPAGGGKPNMYAADLVELLKSVGDFDISVAAYPEVHPEAKSAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPQWMSQMFA
GLDDDPETRKFVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPA
>A0A3N5H0E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MLDSPSAAPAAHPAVRELLADASIEVSARDLHDAASTVREVGAGRQVFIPWTPNVGPGQL
VAATARARELGLVPVPHVVARRIASESAARELLAQLRRNGAESVLVIGGDLPEPAGPYRS
GYALMRTGLLQASGLAEVGVAGYPEGHPRIAAPALRAELDLKLDYARQSGLRVFVVSQFC
FDGALIARWVGDLRARGVAVPVRAGVAGPTTLTKLLKLGVQCGVGHSLRALRGRLGALAR
LAATHEPGDVIRDLAEARLAAPSLDPLSVHVFAFGGIGPTARWLGPAHAAIEA
>A0A3A0ESN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MDPGDAAIVRLARNASIETSTRNVADVGGYARMLPSGSDVYITFLPGTPYHHILSTATRL
QQVGLNPVPHLAARRFASAAAVADFLERLRDQAGVTRVLLVAGDSDAAAGPFDSSLQVLE
TGVFEACAIRSIGVAAYPEGHRRISQQALDDALDRKIRYADAHGLELFVVSQFCFEPQRV
LDWLVRLRARGVTAPVRIGVAGPATVRTLLAYALRCGIGTSMKALGSQPVSLTRMLARHD
PDDLARAIAPRAAGLGVAGLHVFAFGNFADSAQWLRDAAAGRCGAEALDPARR
>A0A257NB73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium NSP1-1|TrEMBL
MQSQKTHPQLFSFEFYPPKTEEGAENLLIVQSKLAKLNPDFFSVTFGAGGSTRDKTFDTV
IAIQAKGIAAAPHLSCVASTKDNIRAILKDYQDNGIAKIVALRGDLPSGMMSAGEFRYAN
ELVEFIRQETGDYFQIHVAAYPEVHPQSTNATEDFKNFKRKVEAGANAAITQYFYNAEAY
FYFVDTCEQNGITIPIVPGIMPITQYAQLFRFSEMCGADIPRWMRKRLESYGDNREAVQS
FGLDLVSNLCQRLLDGGAPGLHFYTMNQAAPTLAILENLQIK
>A0A4R1RUL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenispora ethanolica|TrEMBL
MRIADLYAKKKPVISLEIFPPNPDYPLETIYNTLEQLRDLNPDYISVTYGAGGANRARTV
EIAAHIKQAYQIETMAHLTCVGHSPEEIDEMGARLQENQIENVLALRGDPPRGQSNVTFQ
PGHFRYAAELIRYLRQKSQFCIGAAAYAEGHVECQRWQDDWNYLREKVEAGVDFLVTQLY
FDNRVFYNFKENLLRMGLNLPVAAGIMPVLESKQIRRMVYLSGASIPARLLQLLDKYADN
PADFEKAGIEYAINQMNDLLANGVEGIHYYTMNRAEQTRKVFSGLAR
>Q5GW57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYADDADAVRAFGADVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A7W5BEZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia violacea|TrEMBL
MASHNFSIEFFPPKTAEGAEKLRATRAKLSELHPKYFSVTFGAGGSTQRGTLDTVLEIMA
AGEDAAPHLSCVGGTRESIRAILSEYKAHGIKRLVALRGDLPSGYGAAGEFRYANELVEF
VRQETGDWFHIEVAAYPEVHPQARSPQDDLQAFVRKVDAGANAAITQYFYNADAYFQFVE
QAQKAGVTVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTQLCERLLQGGAPGLHFYSMNQAAATTALWQRLVKD
>A0A4V2WAD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Laceyella sacchari|TrEMBL
MGRPNLIERLRSELLVGDGAMTTYLYQQGVSIGECTEELVLSDPKLVAGVHQAYYEAGAR
VIETHTYGANRERLTRYGLEGKVTRLNREAVRLARESVGDDAYILGSIGSICAGRVPAYD
EEEYRDMYEEQATALLHAGVDGILLETFLDVKEMLLAVEVIRPLTNLPLLAQFSMLEVGR
TRDAFSISTAFQLLAEQGVDGVGLNCRLGPMELLRGLEKTVVPEQLVITAFPNASRLGIT
DGELAYKSNPAYFEQTAELLVEQGVSLLGGCCGTTPEHIRLLAQSLKGRKPVPRRNPQNR
ETAQPVAVEITERVKPTVVEKVRHKRTIVCEFDTPKDLDISAFLHGASRLQQAGVDAITM
ADNSLATARMSNLALGAILKEKMGIEPLVHVACRDRNLLGQQSHLMGLHALGIDQILVIT
GDPTRMGDLPGASSIYDVTSFELIRMVKQLNEGISFAGRQLKQKARFVVGAAFNPHVRQL
DAAVRRLEKKVEAGADFIMTQPVYDAQGIIDVHEATKHIPIPIFIGIMPLTGYRNALFLH
NEVPGIKISPEVLKRMEQQPDKAAGRREGVAIAKELLEVALSRFNGIYLITPFSYWQMSE
ELIRFIHQYDSQHIALRA
>A0A2H5VM43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR08|TrEMBL
MGTAFLDRLNREVLLADGAMGTLLLARGVEPKALMEQNLTRPELIREIHLEYIRAGAQVI
ETNTFLANRLRLAEYGLESELEAINRAAVRIAREAVRMSGEEVFVAGSVGPLGALVKPYG
NLTLTDLSAAYVEQIGILVDEGVDVIIIETHPSLLEALEAVRAARTVSPTTPVIAQMTFL
EDGKSKFGDDLRRSLEALAAADADVVGVNCSGPQMTYDIIYDFLTTTELPVSIMPNAGVP
QFIGGRTIYLSSPEYLREYARRFVEAGANILGGCCGTTPEHIRAMSAVVRGQVPRRVRQR
VIVSVGGEEAPAAPSTASLPTRFRERLGREFVVTVEVHPPRGVDYRAEIEMIRRLARCGV
DAVSIHDPPGARVSLSGLVFAHVVQTQAGVEAIWHLSCRDRTLAMVHAELLGAAVLGVRN
ILALTGEAASVGELPRAPSAHDVSATGLVKIIEGLNRGRTLMGNDIGAPTDFRVGVLVQI
GADDLEAELRKLEERVQAGAHFIVTTPVFDLERFDVFVKHIAAFRLPILVGVLPLKSARH
AEFLHHEVPGIAIPEAIRRRLHRAQGDEATEGLRIARELIAALRPHVAGLHVIPPAERWD
ALPDFLRTCLSQESAAGSLGA
>A0A6G2MRR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4946|TrEMBL
MRPGERSYSFEFFPPRTDTGERGLWQAVRRVEALSPAFVSVTYGAGGSSRERTISVTERI
RTETTLRPVAHLTAVGHSVAELRRIIGRYADAGIRDVLALRGDPPGDPQGEWRPHPEGLR
YAAELIELLKSVGAFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAVTQMFFRPED
YLRLRDRVAAAGCDVPVIPGIMPATSFAQIHRFAQLSNAAFPPDLAQRLEAVRDRPDLGH
RVGVEHATAMCELLLAEGAPGLHYITLNNSSAAVEIHRNLCPHRAAAPLPAA
>M6Y6H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira noguchii str. 2001034031|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSLLDPDFVTVTYGAGGSTRDK
TVQILSQISKNYSVPTVSHFTCVGANKDQILETLKGIRSSGIVNLMALRGDPPKGEGEFK
KVENGFGNATELISFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVKNLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A2H5YX42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR27|TrEMBL
MTVTSSPQHGVEGTLETALALRRAGYRVVPHLAARAIRDRAQLADLWRQYAAAGVDEVFI
VGGDQEQPAGEFATSLDLVKAVVELDPLPQRVGITSYPEGHPHIPADVLERDLLAKQPYA
QYAVTNLVFDPEVFVHWLNTMRARGFTLPIYIGLPGTLRIDRLIRIGMRLGLGSSLRYLE
KQRGLVGRLLTGGGLRYDPGEFLDEVARQPAEARTGIIGVHWYSFNSVGSVVNWVAERQQ
RLGC
>A0A3G9IVY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus baekrokdamisoli|TrEMBL
MKISVELIPRDIEQLDHELQLIQSSFSEVNTINIPDLLRFSIRSWEGAVRTLPYYENCIP
HIRAIDFNLKENLGLLDYLNANNITQVLAVTGDLPQDMNRNVYPTTSVDFIRIIKQECPH
IKVYSAIDPYRNNFKEEHEYIQRKLDAGADGFFTQPFFDLRLMEVYYELLGNEDVFWGVS
PVISQKSRNYWETKNHAIFPKRFEPTLEWNIDFAREVLNFSRATGTNMYFMPIRVNLEAY
LNGVFK
>A0A502EPF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium pectinovorum|TrEMBL
MKVTEHIENAKGNTLFSFELIPPQKGKSIQDLYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
LMALRGDAMKDEQSFVPKAGGNRFAIDLVRQINDLNCGKYLHEVMDVDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFNFVEKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNVEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A1I4V9N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter pelagius|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQTVRNKLAEVEPDFFSVTFGAGGSTRDRTIETV
LSLHKQGISTAPHLSCVGGTREEIGELLDLYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIERLEKVGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTRMCERLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A0H2X4J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. campestris (strain 8004)|TrEMBL
MSPDPPSRAATITDAYSLEVGAHDMPALTAAAPQIMRGSSMFIPYLPSQNDDARLAAAQR
VRALGFAPMPHLSARRIASRYALQAFVRRAVDEAGVERCLVIAGDAPSAVGPFSDSVSLI
ETGVFERSGIKAIGVAGHPEGHPSMPASAQWDVLERKCRSIAERGMAPLIVTQFAFDADT
VLTWLEALRARGIAHPVHVGVPGPAGVAVLARYAARCGVGACASMLSKYGISLGKLFGTA
GPDRFVDRLTAGLSEAHGDVSLHFYPFGGIAQSVAWVEQYRSRHARPLAD
>A0A1J5BHC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium CG2_30_68_42|TrEMBL
MARTFSFEFFPPQTAEGVEKLRATRRQLAQLEPAFFSCTFGAGGSTREHTLETVLEIQAE
GLCAAPHLSCIGSTRENIAALLDRYREAGVRRIVALRGDLPSGMAAAGEFRYANELVSFI
RERTGDWFHIEVAAYPEYHPQAKSPAEDLANFKRKVEAGADSAITQYFYNADAYEHFVGE
CAAIGVDVPIVPGIMPIANFTKIARFSDACGAEIPRWMRKKFESFGDDAASVRSFGLDVV
TALCERLLAAGAPGLHFYTLNQAGLTCTIWERLGLGSRDRE
>A0A4Y7RVL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelotomaculum propionicicum|TrEMBL
MKYLSKLHQALAEGHFAVTAEIGPPKHASAQGVIRHAQMLQSCVDAANITDCQTAIVRLS
SIAAGAHILGCGVEPIVQMTCRDRNRIAIQADLLGAYSLGMRNLLCLSGDHQKFGNHPSA
KNVYDLDSVQLISLMRRMRDESKFFCGEEIKEHEPRFFIGAVANPFADPFEYRVDRLEKK
IEAGAQFIQTQCVFDMERFERFMEMVRARGLDQRAHILAGVTPLKSWRAARYLQTGVSGM
IVPDTLVERLKNAADPKEGIKVCIEQIRHIKEKVRGVHGVHIMAIAWEEAVPEIAERAGL
LPRPGLQRRAESID
>A0A6M8V066|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium|TrEMBL
MKVIDHLEKAKEPLISFELIPPKRGGDITDVLHVLDGIIKFRPPFIDITSHSAEVIYEET
SEGIKKKVKRKRPGTLGICALIQNKYNVDAVPHILVKGFTREETEDFMIELNYLGIDNIL
AIRGDDSGYEKPIPVGRSANRNSVELVEQIMRMNKGIYLEESLLDAKPTNFCVGVGGYPE
KHFEAPNLKADIKFAKEKVDAGAEYIVTQMYYDNKFYFEYVDKCREAGINVPIIPGLKIL
TSKAQLHSIPKDFHVTIPSALSDEIEKAKPEEVMNIGVEWAANQVLELLDKNVPSVHFYV
MLNARPTNMVMERLKLFNKVF
>A0A8J8BGL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovermiculus sp|TrEMBL
MNEKTPSKLEKVLAAGHMAVSSECGPPRGSDPEVIKKKAEMIKGHVDAINITDNQTSVTR
LCSLAACIQLKLMGVEPILQMVTRDRNRIALQSDILGAASFDIHNILCLSGDHQSFGDCA
QGQNVHDLDSMQLIQTVRHMRNEGKFLGGDEIKRPPQMFVGAAANPFADPFEIRVPRLAK
KVAAGVEFIQTQCIFNLDKFEEWMKGVRDRGLHEKTHIMAGITPFKSAGMARFMQKRVPG
MDIPDHVVKRMADTPKDKQAAEGITIAVESIEQLKECEGVHGFHIMAIEWEEKVPEIAER
SGLYPRPEV
>Q752W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)|TrEMBL
MSKIDVKYSELNRPSLSLEFFPPKTDSGKSNLLARIERMSAMDPLFITVTWGAGGSTAEK
TLELAALAQRELNIPVCMHLTCTNMDRTILDKALMRAKEAGIRNILALRGDMPLAADEEE
HVDGGFLYAIDLVRYIKMQYGDYFCIGVAAYPDGHCEGEADGMEQDPMRDLPYLKEKVEA
GASFVITQLFYDVEKFLAFEELFRREISETIPVFPGLMPINSFMLFNRAAKLSHASIPSH
ILDRFPHHIRHDDLKVKEIGVEIMVEIVNKVWERTSGRIKCFHFYTLNLEKSIAQIVTQS
PVLSRIIDEDSEVEDSSGDVVVEDANASEADDLSYKKRRRQSSMQGEPESGMVMLDGPRR
FSVRGAVPSRKVVISISKGSGTLGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSLKVSNK
KAYQIWGYPSTLNDIKSLFIGYLEGSIEALPWCDLGLSPETALIQEELIGLNQRGFLTLA
SQPATNSTPSADKIFGWGPPGGVVYQKAFVELFVEKARWEAELKPRLEGPDSKFSYYFGD
SAGSFASNMAPESSSVVTWGVFPNSQILQTTIIEEESFKAWRDEAFSIWLSWSKLFPRNS
PHNAFLRGIHRDYCLVSIVHHDFSSVDELWETLLR
>A0A1E4WUJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ENNP23|TrEMBL
MSQDRRYSFEFFPAKTEAGHEKLLATARTFAGYNPDFFSCTYGAGGSTRDRTLQTVLQLD
GEIQVPTAPHLSCVGDSKAELRALLAHYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VAFIRAETGDHFHIEVAAYPEVHPQARNFEEDLKHFVNKVKAGADSAITQYFFNADSYFY
FVDRARQQGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYADDTASIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A435T7B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.003.02.2.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A3D3TF22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dysgonomonas sp|TrEMBL
MKVRVTDLINKSNKTAFSFEILPPLKGNDIQKVYKIIDKLVEFDPQYINITTHHSEYIYK
EMPDGTILKTNIRKRPGTVAVAAAIQNKYNTVAIPHLICKGFTRAETEYALIDLNFLGVY
NLLLLRGDANKLQPDQMKGDGNNYATDLQKQVNDFNTGISEDGTVFEKFETPFSYGMACY
PEKHEEAPNIESDIRYMKMKQDNGAEYFVTQMFFDNSKYFSFVDRCRAEGITVPIIPGVK
PIVLKNQLNVLPKIFRSDIPEELASELRKCKTDPEAREIGIEWGIKQCKELMQHGVPSIH
FYSLMASESIRRIAKEVY
>A0A318CYW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kangiella spongicola|TrEMBL
QVFFDNDLYHRYVDRVRARGIEIPVVPGIMPMHNFKQARNFVTRAGTSVPDWLAEKFEGL
DNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGAQKAA
>M1X082|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Richelia intracellularis HM01|TrEMBL
MNAFRQAIEAGSFLVTAEVTPPKGGDPSHMIQMAATLKGRVHAVNITDGSRAVLRMSSLS
ASAILLQHGIEPICQMACRDRNRIGLQADLMGAYALGIRNVLALTGDPVKVGDNPEAKGV
FDLEAIRLLQTIDKLNHGFDYNEKPLINGGLDLLVGAAVDPQSRSWSGLQKRFERKVKAG
ARFFQSQLVTDFELLDKFMNTIAAGCNIPIIAGVFLLKSAKNANFINRMVPGVNIPERII
ERLEGAKDPLEEGVKIAAEQVKAARDICRGVHIMAVKREDLVSPILDIAGIKPVIELGLE
TKVPK
>A0A078KBI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Evansia muelleri|TrEMBL
MILTKLDISFEFFPPITKLGKKNLLISIDKLIKFNPKFFSITFGACGNKNTFDTVLKIKN
KCLYVNIVPHLSCISIKRNELINLLYKYKVSGIKSIVVLRGDKYYNNYIAELHYANELIQ
FIRDESGNYFELIVGAYPEMHSEAFNFEKDLNNFANKMKVGANKAITQYFYDARAYFNFI
ECLKKIGFEKPIIPGIMPINNFNKISHFSNICGASIPRWICKKFEAYGDDNKSAIEFSKE
IMIKICKNLIEGGAPGLHFYTLNNVEPSIAILHELKNIIY
>A0A3E1D0F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrotoga sp. MKT|TrEMBL
MTNSKSFSFEFFPPQTQEGANKLASARRQLAILEPTFFSVTFGAGGSTRERTLEAVQQIK
ADGYEAAPHLSCVGSTRENIRTILHTYKNMGIKRIVALRGDLPSGMATSGEFHYANELVS
FIRAETGEHFHIEVAAYPEFHPQAKSPRDDLLNFKRKVMAGANSAITQYFYNADGYFRFV
EECRKLGVTLPIVPGVMPIMKFSQLARFSDLCGAEIPRSIRKILESYGDDNESVQAFGLD
VVTQLCERLLAGGAPGLHFYTLNQSAPSMEIWKRLGL
>E1YDH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MCGSCCFGCSRSIKQLYETAKGEKYSMRVTRLYESKKPVISMEFFPPRNEKAAQTFSKTI
DDLAELKPDYMSITFGAGGSTRDGSYQTVKEVMIDKKQPAVAYIAGYGLGPEEIIGVLDR
YQALGVKTIFVIRGDKPREDTFTPHTQSFAHASEMIAFIKERYDFTLGCAGYPEGHVEAQ
SLDKDIEYLKCKVDNGAEYVVAQYFYNNAFFFDYVKKCRAAGVAVPIIPGIMPVYTAKMT
KMLCKVCGASIPADLQSRLDTVDADDKNAVLKLGIDFATGQCRGLLKEGVNGLHFYTMDR
SHSTAQILNKLKEEKLL
>A0A445N145|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MPLQDKIRSGKFVVLGEFEPPKGTDFSSLLESAMQSRGRVDAIVIPEMANAVLKASSLGA
CAFFQKAGIETVFQVCCRDRNSLALQADILAAGALGIPNIMAVAGEEIKFGDHPQARTVN
DLDLTELLDAINRLSSGRDLAGIELRGVPHFCVGSTMDTSVSGGLMDIELENLKKKISLG
VEYVITNPVFDLRRFQQFLKRVDTTRIKLIPTVLLLKSAGMARYIDKNVKGMSVPSEIIR
DIQKAPDKGKECIRIAGETIARLKDMGMAGVLISTIGWEKYLPLVMDAAKI
>A0A0T1XQ24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Root482|TrEMBL
MAHIDENPLGRHLPLDPVPGHSSRGRLERVLRRGEFAVTAELNPPDSADPEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNGKFLSGRKLTTPPQVFLGA
AINPFAPPYDFRPHRLGKKIEAGAQFVQSQYCFDVPMFRDYMTRVRDLGFDEQCFILVGV
GPLASAKTANWIRNNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIKGVSGVH
VMAYRQEEYVAEIVHESGVLKGRTPWTRESNPGDGRVAERLDALKGGKTENQEQMAEVAA
QQSH
>A0A3S1UK37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.15.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFD
>A0A3G1KPK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Formimonas warabiya|TrEMBL
MKKRDNVILFGRGGNKVENRFKESLLNPNTMSVTWELVPGRGAREKSQESALEAAEQAAK
GGKIHALTITDNPGGNPAMLADYLGEEILKRGIEPLVHFTCKDKNRNQMESQLYALDRAQ
VRSLLVMTGDYPVTGFQGRPKPVFDIDPTHALELIGEMNQGLEYPGLKGTVKHQASDFFA
GAAVSPFKAHEAEQMVQYYKLKKKVASGAQFIVPQLGYDARKFHELIQFMRQNNLNVPVV
GNIYILPYGAGKLMNENKVPGCVVTNKLLAELDRERTLADKGVEARLLRAAKMYAFMKGM
GFNGVHIGGHGIKYAQVEYIIEKGEELSANWMDLVHEFDYPMDNGFYYYQKDEKTGLNSE
IPTERKGRPLDTKVEFIYRVSRVFHSLVFEPHKNFFGLMKGISKFVEGKKIEKCYHFLEH
MAKVTLYDCKDCGDCALIDLAYACPMSQCPKNQRNGACGGSYNGWCEVHPEKKKCVYVRA
YARLKDYGHESQLDSYHVSPCNWDLYQTSSWINFYLGKDHSAERLGLNKDSKKVDAGGKA
VGK
>A0A1Q6DLV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium DB1|TrEMBL
MTEESKDKDGAPPFSPFQRSLHSPEEFTITFELVPSRGGRNRRIDRTLGLARDLALDGRI
RAVSITDNAGGSPALSPEVLGLEIKAMGLDVISHFSCKDKNRNEMESQLFGWDRRGLHNL
LVISGDYPKEGYSGHPKPVFDLDSVHVVDMLRLMNQGRFIRHENQPTAFFKGVAVSPFKL
TEAEQLMQYAKLRRKIAAGADYVITQLGFDARKYHEALLFMQRHDLRLPVLGSVFVPTLK
LAEIMYQGGVPGCIVSEKLYREMQKEATAADKGKKARLTRAAKLLAILRHMDYNGAHIGG
PGLRMEDFDFMLTEARKYLPQAGELVGDVNFWPEEGFYLFHKDEHTGLNREEMNQCGQGF
AAFRPVFSLARLVHNAAFDPRSPLFPFCRTSCLALHDSCLKKPFFALEHVSKFLLFDCQN
CGDCTLAGHGYLCPQSGCAKYMLNGPCGGSRDGWCEVYPGKKRCLYVKAYERNPSSASPD
EDAQSFEPPRNWLLNGSSSWANFYQGRDNRGEQTTREPKKTNNNFS
>A0A2N2AQ28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-8|TrEMBL
MSAGKLQEILSQGKFAVTAECGPPRGANAEVVWKKGALLKGYVDAVNVTDNQTAIVRMSS
IAACAHLIQMGIEPVMQMVTRDRNRLALQSDIMGAYSLGIRNILCLSGDHQIFGSQPEAM
NVWDIDCMHLIHTVKDMRETGKDMSGFALDEPPKMFIGAAENPFADPFEFRVLRLAKKAA
AGANFIQTQCIYDIARFKEWIHVAYEQGLTEQVHILGGVTPLKSAGMANYMATKVAGITI
PEAIIKRLEATPKEKAAAEGMKICLETIQELREIKGVHGVHIMAIEAEDKVPEIVKLAGL
YPRP
>A0A0D1NWR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium elkanii|TrEMBL
MTETVSPVPNGHRAPNVPKISFEFFPPKTEEMERTLWDTINRLAPLTPNFVSVTYGAGGS
TRERTHATIARILRETDLLPAAHLTCVSSSRSEIDEIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAGIKKRHADIEISVSAYPEKHPEAADFDADIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDKVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPGWLAE
KFDGLDHDAETRKLVAATVAAGQVQKLFKRGVDTFHFYTMNRADLVFAVSHLLGIRPNGA
QKAA
>A0A357LJX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTPLEISFEFFPPKNLEASFRLWDTVQVLAPLEPRFISVTYGAGGTTRDLTRDAVSALHK
SSGLRVAAHLTCVNSSRQETLAVAQSFAAAGISDIVALRGDPPKGEGSFTPHPEGFQSSL
ELISALAQSGDFTLRVAAYPEGHPEAESTSTDIDFLKRKIDAGASEALTQFFFEAETFLR
FRDACDKAGIKVPITPGILPIENWQGTRRFAKACNAKVPNWLTDAFSKAERDDREDLLAT
AVCTELCSQLIDEGVDALHFYTLNRPDLTRDICHALGITAAVKLEKIA
>A0A0B5F5H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albus (strain ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 / NBRC 107858)|TrEMBL
MLAAQATTYSFEFHAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRDGTVKATEQ
IVADTTLTPIAHLTAVDHSVAQLRNIIGQYADAGIRNMLAVRGDPPGDPTAEWVAHPEGL
TYAAELVELIKESGDFCVGVAAFPEMHPRSTREESDIRHFVDKCRAGADYAITQMFFRPE
SYLRLRDQVAAAACDTPIIPEVMPVTSVRMLERLPQLSNASIPAELKERILAAKDDPAAV
RSIGIDFATEFCARLLAEGVPGLHFITLNNSTASLEIYENLGLHHTPA
>A0A0M0WEV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. FJAT-14745|TrEMBL
MGLLERLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLEEI
LATVDEQATVLLAGNPDGLLLETYYDFEELTATLTMLRGKTKLPIIAQVSMHEPGVLQNG
MSLNNALHELEALGADIVGVNCRLGPYHTIQAFEGVELPKKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVEEKYAKPEKVAV
VREAEPPNYEPLHVKVKRERSVIVELDTPRHLEIEGFIEGAKKLYEAGADVVMMADNSLA
SPRISNVAMGALLKETHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVSR
LEKKIEHGADYFISQPVYSKEKIVEIYEATKHLETPIYIGIMPVTSYKSAEFLHHEVPGI
KLSDDALARMKACGDDKERATLEGIAIAKELVEVAAEYFNGIYLITPFLRYDMTLELMKF
IEQFDEQKKGVSING
>A7Z390|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42)|TrEMBL
MGLLQDLKERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LWEALRSIADLGADIAGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTEKEVKIRREEEVI
SVSNERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A101G544|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotomaculum sp. 46_296|TrEMBL
MKTAELFKIKTVLSFEVFPPKKTSPLDTIYKTLNELSNLSPDFISVTYSAGGSENSESTI
AISSTIKNQYHIESVAHLTCISQTKEEVLCLLERLKDNNIENILALRGDINPDIPPKQDF
KYASDLVSFIKKNSDFNIIAACYPEGHSEAVSIAEDIRNLKIKVENGVDHLISQLFFDNN
YFYTFLERVEHAGITVPIEAGIMPVVNKKQIERMVSLCGADLPKKFTAMMNRYENNPVAM
RDAGIAYAVDQIVDLVSQGVDGIHLYTMNNAFIAQKICEAVKSLFISPL
>E8KGK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus ureae ATCC 25976|TrEMBL
MSYAKEIDHLNQSVADLNGQINVSFEFFPPKNEKIETMLWDSIHRLKALKPKFVSVTYGS
NSGERTRTHSIVKNIQQETGILAAPHLTGIDASPDELRTIAKDYWDNGIRNIVALRGDEP
AGYAKKPFYAADLVRLLKEVADFDISVAAYPEVHPEAKSTQADLIYLKQKIEAGANRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKVTNVRIPSWMQKMYQGL
EDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRSELTYAICHMLGVRP
>A0A2N7D6L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 10N.286.49.C2|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSTPTMEETLWKSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKNETGLVAAPHLTCIDASRNELIDIAEDYWSNGIQSIVALRGD
IPEGGGQPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQASRFAGMNKVKVPGWMQKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRSEMTYALCHTLGVRP
>M2A458|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula europaea 6C|TrEMBL
MICLMTLASVYQSTDCAISFELFPPKTSEGVDLLCKNVERLMQFGPKYFTCTYGAGGSSQ
GTTLEVLQKVKEITSLPVASHLTCVGSTVKELETYLTEASRIGVDYIVALRGDPPKGTTQ
FEVTEGGLKYANELVELIRGQFSDLGIAVAGYPETHQEAVDFQTDLTNLKRKVDAGADIV
ITQLFYDNDDFYRFRDACQKIGIEVPIVPGILPVTNFKQAKRIASMCKAAIPQSLESAMT
EAGDDQDQFRVGVEHARQQTIDLVNNGVPGIHYYVLNKSEAAADLLDGLSLTSC
>X6GGF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L48C026A00|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>G0A3L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas methanica (strain MC09)|TrEMBL
MNISFEIVPRTLDAFEKQYAFVQSLNDCINIINVPDIQRFAMRSWQLARHVDRNQYRFIP
HFRAIDFKIESGELYRIIEGYQLDNVLLVTGDPPEGLKRSYCNTDVVDLIRAVRRRFPKL
NIYAGFDPHRQGLQHECHYIQRKADAGANGFFSQPFYDHRLVELFAEHMDGLETYIGISP
VVTSASQNYWEVKNHVKFPKHFRPDYDWNVEFANRLIGSAAENGWHVYFMPIKVELKKYF
ERIKLASPSPTTLSVTG
>A0A1V3RYK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp. A37|TrEMBL
MALPLSFEFFPPKTPEGTEKLRAVRQQLYVQKPEFCSVTYGAGGSTHQGTFDTVGEILAE
GVSAASHFSCIGATKASVREQLATLKAMGVKRLVALRGDLPSGYGIGGEFHHASDLVAFI
REETGRDFHIEVAAYPEIHPQAKSPEADLQAYVTKIKAGADSAITQYFYNSDAYFRFVDD
AHKLGATAPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQGYGDDIASIKAFGLDVV
TDLCDQLRSAGVPALHFYTMNQSAATLEIVKRLQLG
>V9X9U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus pyridinivorans SB3094|TrEMBL
MTSDFVRATEDGGISRTPSIVDRLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERL
GPAFVSMTYGAGGSTRDRTVRVTGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGI
TNILALRGDPPGNPLGEWEKHPEGLEYADELVRLVRELGDFHVGVASFPEGHHRSPDLDH
DTRYLVQKLRAGAEYSITQMFFDVEHYLRLRDRVVACDAEQGLKPIIPEIMPITSLRSAR
RSLELSGSHLPPVLEERLRRAAGDGPEENRAAVREVGIEVATEMCERLISEGAPCLHFIT
LNFARATGEVLDRLGYELEAPAAVQPA
>A0A838XWV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR86 cluster bacterium|TrEMBL
MEQKINTFSQKLVESYSIEVTPRSAANIESFKDVLPQNTRVYIAHIEDEDIQSMVNTAKR
LNDEGFHAMPHFPARAIQNEAVLNHWISMYKNEAGVDEALLLAGGRSKPLGDFESSIELI
ESGKFDQAGFKRLHIAGHPEGNKDIDPDGGETNVSQALSWKQEFSNRTDASMAITTQFCF
DAAVVKKWADNIKSKGIDIPIHIGIAGPAKLQTLIKFSIECGVGASMKVLTKRARDITKL
LLPYKPTQILNDLGEYKSQDPSFNIEQVHFFPLGGIKKAAEWAKEYSN
>A0A6B8LMQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium catenulatum subsp. kashiwanohense|TrEMBL
MHSPMFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVS
EYGIPSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFEHASDLAA
YIRQQRPGMKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KARTAGIDVPIEAGIMPVMNVKSVLNMSSKCQSKIPEKLGIMLDKWGSDKALLKEAGIAY
ASEQICDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A8E0DKB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus M899|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A6A5K6Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Decorospora gaudefroyi|TrEMBL
MHISQKLAQAREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHSFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKAKLDDALREAYQSGCTNILALRGDPPREKEK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSERSDDNDDVDELIDHLKEKIDAGGTF
IVTQMFYDTDLFLEWVGKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTKCNIPKPWTEAL
EPVKNDDVEVREVGKTLVADMCRRLIDAGILHLHFYTMNLAQATRMVLEELELLPDMESP
LEKPLPWRPSLALNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGSPMSIKDLSDLFVRYMGGKLESLPWSEQPITPEAGSIQEDLID
LNRRGFLTINSQPAVNGARSSDPVFGWGPRNGYVYQKAYLEVFVSPEYIAEIITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDVIDTWYLLNIVHNDFHATRGIFPIFDGLEVEDMDRPLHNPSADL
PTVNGHDATNGTSNTGGINNEKHKPGNKEGTSLIDAAKAAAVEVTNGIKGLSASS
>A0A7G9QYV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycicoccus endophyticus|TrEMBL
MSNELPTVALVRLLEGARYEVMPTASVVDAVGEHVPPSVTVTVTAAPGKGLEATLSTATT
LARAGWPVVPHLAARMLTGRGELQEVVARLAEAGVTAAFVPGGDADPPAGDYDCALDLLR
DLATMEHPFTQVGITGYPESHPTIDDDVTVQAMWDKRAYATHIVSNMTFDAEHLGTWCER
VRRRRVELPLLVGVPGPVERTKLLGMATKIGVGESLRFLRKQKSVFARIAAPGFSSDRFV
SRVAALSANPALGIAGLHVFTFNQVGVVETWRQGMLARAREERVHPTGRGGHQDG
>R5FA37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium bolteae CAG:59|TrEMBL
MKTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTRDDVLLILEQLKEQKIENILALRGDRTADREPAGDF
RYAADLVEFIKNHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFRERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFISMMERYGDNPIAM
RDAGIAYAVDQIVDLAAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>A0A2M8A691|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium CG_4_9_14_3_um_filter_40_17|TrEMBL
MKVTEHIESGNGKTLFSFEILPPLKGQTIQSIFDHIDPLIEFKPPFIDVTYHREEYDFHE
VTSGLLRKKVVRKRPGTVGICAAIQNRYDIDAVPHILCGGFTKEDTENLLIDLGFLGIDN
VVALRGDAVKSETYFKPEKEGHAYAEELVKQIVAMNNGKYLDDSLENSAHTDFCIGVAGY
PEKHMEAPSMESDFHFLKKKIKNGAHYIITQMFFDNKKYFDFVDRCRKEDIDVPIIPGLK
PLATKKQLNLIPHRFKVDLPDDLVMEVVRCKDDKEVRQLGVDWCIEQSKGLIAAGVPVLH
YYSMGKSDNIQAVAKAVF
>A0A2A4X4U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR86 cluster bacterium|TrEMBL
MDSSNPSKYSIEFFPPRTGAGESKLDTVHAELNKLNPDFFSVTYGAGGSTKSGTQQIVLR
YQAAGSHCAPHLSFGGSDEEELRQLLQTYIDVGIKRLVALRGDMPSGVGAAVQHRYANEL
VDFIRAETGDHFHIDVACYPETHPESKSYASDVDFFKRKVDAGANSAITQYFYNPDAYFR
FVDYCRTAGIDIPIVPGIMPITNYANLARFSANCGAEIPRWLDKRLLGFGDDMESVRSFG
IDVVTELCEDLLQGGAPGLHFYSMNLSQAVTQIWTNLDLGNRPQRELL
>A0A516NLJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia otitidiscaviarum|TrEMBL
MYSPSESGLSGVGRPARISPTASGVPSVVQSLRRHAAGPRVPFSVEFNPPRDAAGEARLW
RAVREFERMHPAFVSMTYGAGGSTKDRTARITGQLAQQTTLLPVAHLTAVGHSVAELRAL
VGSYADCGIRNILVLRGDPPGDPLGAWHRHPDGVEYAEELVRIVRDLGDFHVGVASFPQG
HHRSPDLDTDTAFLAAKLRAGADYSITQMFFDVEHYLRLRDRVLAADPIQGAKPIIPELM
PITSMRTVARAEELSGRALPAAVLDRLRRAAGDGPEENRAAVRRVGIEIATEMAQRLIDE
GAPCLHFITLNFAKATTEVLTNLGYEVTAAPLSA
>A0A2A5B8S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR86 cluster bacterium|TrEMBL
MESSSPANDVKFSIEFFPPRTEAGEAKLDIVHAELSALGPDFFSVTYGAGGSTKSGTKKT
VLRYQQAGSELAPHLSFGGTDEDEIRQLLESYKTAGIKRLVALRGDLPSGTGNAAQHRYA
NELVKFIRSETGDYFNIDVACYPEVHPESKSYASDIEFFKQKVDAGANSAITQYFYNPDA
YFRFIDYCAAANIDIPIVPGIMPITNYENLTRFSASCGAEIPRWLAKRLQGFGDDIDGLR
NFGIDVVSELCDDLLAGGAPGLHFYSMNLSKNVSQIWNNLSLSNESEINKN
>A0A0F2DYJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus infantis|TrEMBL
MSRQTPSLSFEVFPPNPSVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFINEQAPHFDVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQP
>A0A1H0F0H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas arsenicoxydans|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYTPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKTAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1M5XM72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium erythrophlei|TrEMBL
MTEVTPPASDSHRALKAPAISFEFFPPKTEEMERNLWETIKRLAPLAPNFVSVTYGAGGS
TRERTHSTIARILTETRLTPAAHLTCVDAPCADVDDVVAHYHEVGVRHIVALRGDPTSGL
GGVYAPHPQGYRSSADLVAAIRRRHGDIEVTVSAYPEKHPESPSFDADIDMLEAKVDAGA
TRAITQFFFDNDLYFRYLDRVRARGIGIPIVPGILPVQNFKQAANFAKRTGASMPDWLAE
KFDGLDDDPETRKLVAAAVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGLRPHGA
QKAA
>A0A2M7NSC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG_4_10_14_3_um_filter_49_12_50_7|TrEMBL
DLIKHIKKEHSFSAGAAFYPEGHFQSPSLADDITHIAGKFAAGADFGISQMFFDNRYYYD
FLDRAAKAGIKKPLIPGIMPILNFEKIKELASSSAKVAIPDKLERLMN
>A0A7W8U739|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium giardinii|TrEMBL
MPIHTLYPAERGNLRLSFEYFPPKNDEMETQLFQTVENLAAFNPAFVTMTYGAGGSTKAR
SLTAVRRMIHEAGFPNTAAHLTCVGAAKDDVDAIVSEFIDGGVRHFVALRGDPQGGIGAR
YEPFPGGYENAAALVAAIRGRGDFEISVSAYPEKHPESPDVATDIDMLKRKVDSGATRAL
TQFFFDNNDFERYLERVRRAGITIPVVPGILPINNLTQVSKFAGLCGARIPEVVVARLAH
LDESPEERFKEATHIAAEQIVDLARRGVRDFHVYTMNRSPLVAAVCDLVGFERAAPAAAA
SRAAGAAA
>A0A5J4PSQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
QLFYDNRKYFDFVGKARQAGINIPIIPGIKPFKSLSQLTMIPKTFKVDLPEELSHEIRKC
KNDNEACRVGIEWCTVQCKELIAHKVPSIHFYSIAATDSIKEVAKRIY
>A0A5J4PUX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
MHYGLNIINIKIESTLNLRGKELNLILINHYKHFYYFCHIAEYERYMKIIDLISGSEHTA
FSFEILPPLKGTGIGKLYDTIDTLREFTPKYINITT
>V2UEK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter brisouii CIP 110357|TrEMBL
MSALSHYLQQQQFCLVLEQIVSKRTELPPISTLAGLPCVMAFADRVHADDDPSPITLAQS
VSPEQAKLLHFSGKARDVKDLQQFVEQAKQQNLHDVLLLTGDKLKQHNFGHTDPRQRTRY
LESVSALMWVKAHAPEMYCGVAFNPFKYTESEEQAQYLKFEKKQRAGADFVITQLGYDLN
KILKFKQFVDASAQPCPVLACVMPLTYRRAKFMVKQQVAGIEISRHLLQHLKAELQENAA
WAEQRVYARAALQIWIYRHWGLAGIHVSGCQNPEQQALLEQAMAQYQTWTLEQCLMEWNR
LCKIVRGDEMQPDLSAAYPQRQASVLKYQVLQVTHDWLFDSTLAQKIGRFVFQRQFWQQG
LAAKSILAVEHASKHAVVGCESCGQCRLAETLYICPETCPKGLANGPCGGTRLDRCEFAD
RECIHSQKYRLAKQVRQQDILRYELIPAVPVEIRQTSSWVNWFNPKVIDF
>W7B7U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria grandensis FSL F6-0971|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEATRGTGVYIFGTIGGIHGANDARISAPDM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIVANVSMHEPGLL
QSGQTLASALQELADLGADVVGANCRLGPYHMAKALESVPLLENAYLAAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRRGLKSLEPVMSKVVYPIL
ELAELEVAEDAGVRLTDKVKDQFTVLVELDPPRTFDTAKFFEGAKELDEAGVDAITISDN
SLATPRISNMALAAILKHEYDIRPLIHLTTRDHNLIGMHSHIMGFHKLGIQDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALVEAGITVPVFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREADKNGTGREEGMAIAKEIIDAICEHFNGVYIITPFLRYDLSIE
LTKYVQSKEASEQTV
>A0A7X9UWA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri|TrEMBL
MIPTDTPSGASTITDAYSLEVSVKDIGALTNAAPRMPPGSDMFIPYLPGQTEAARLAAAQ
RVRRLGFEPVPHLSARRIGSLEELQAAIARLVGEADVTRCLVIAGDPSTPKGPFADSVSL
IETGVFERSGIRTIGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
IVMTWLEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLASRLTEAHGDVRLHLFPFGGIAQSVEWVAHYRSCEVSQDRVSSVAAD
>A0A5J4Q3J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
WLKKKVEAGAEYAVTQLFYDNNKYFGFVEKARQAGINIPIIPGIKPFKKLSQLSMIPKTF
KVDLPEDLSREILKCKNDDEARQAGIEWCTAQCKELIARKVPSIHFYSIAAADSIREVAR
RIY
>A0A806LMT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus varians|TrEMBL
MGLLEKLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADVIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLEEI
LLTVEEQANVLLAGNPDGLLLETYYDFEELSATLKMLRSKTELPIIAQVSMHEPGVLQNG
MTLNQALHELQALGADVVGVNCRLGPHHTIQAFEGVELPDKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVALRDQGVRLIGGCCGTTPKHIAAAKKYLEELTPVEAKYTKPEKVEI
VREAEPATYEPLHEKVKRERSVIVELDTPRHLEIDGFIQGAKKLYEAGADVVMMADNSLA
SPRISNVAMGALLKETHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKIVEIYEATKHLDAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSDDALSRMKACGEDKERSTLEGIAIAKELVEVAAEYFNGIYLITPFLRYDMTLELMKF
IGQLDEQKKGVSIDG
>A0A7W9DBX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neomicrococcus lactis|TrEMBL
MSTSATPPAKKLVDDFSLEMTGKDVEALEAAAHLIPQGTRINVTFLGNEDLDMRTNAAAS
VRRLGFDPVPHISARRISSESELTDFLQALKEAAAPTKVFAVGGDPETPMGPYEDSLSLI
ETGLFPQYGITEVNIAGYPEGTPVIADDVLWDHLQRKDRALKEQGLDGIILTQFSFDTDP
VTQWISDVRNHGVDLTIRVGVPGPAGIKRLLNYAQRFGVASSAGIAKKYGLSLTNLLGTA
GPDRFINDLASELTEASGDVKLHFYTFGGLSATAEWIQDFRR
>A0A373LCU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF37-20|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A5D0VDU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium|TrEMBL
MSAITSRRSHEVANSPITASFEFFPPKSDKMAETLWGTVERLAPLNPSFVSVTYGAGGTT
RERTHKTVARILKETDLAPAAHLTCVGASREEVDEIVREYWDLGVRHLVALRGDPLEGIG
ARYVPHESGYPYATDLVAGIKKIANFDISVSGYPERHPESGSWQSEIDNLKRKVDAGADR
IITQYFFDNDMFDDYMERIAAAGINVPVIPGILPIQNFEQTMVFSAKCGTSIPQWLARRF
AGLAHDPDTRKLVGVSIACEQVMDLVDRGINDFHFYTMNRADLTFAICHMLGMGSPETKE
DLAA
>A0A5D0VXP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium|TrEMBL
MTDQRLLDNGRLPASTEMSPKQVVEKTELLAHIPAGTKVYVTDLGNTPEDMIVSACRILQ
DSNLTAVPHMAARRYPSLAAFDQRIRRLTQEAGATEVLAIAGEAQTPGPLTCSVKMIETG
LFDALGIRRIAVAGHPEGAPDIQPDVIRAYLTRKHELAASSDAEFRIVTQFGFDPYRVSL
WLDELREWGNRFPVHIGVAGPAKMTTLLKYAAFAGVENSLNFLKKRGGAVVSMLSGYDPE
TMVSPLETRVTSQPASQLAQIHVYPFGGIEKTANWLHGRGSWSFHRSSSTLTANEIA
>A0A355IRL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prolixibacteraceae bacterium|TrEMBL
MKVIDIIKNSEKPIFSFELLPPLKGNDASKIYNTVESLVDFDPKYINITTHRDEMIYKEL
PNGAIEKRVVRKRPGTVAIAAAIQHKYNIPVIPHILCGGFSKSETEHVLIDLNFMGIDNV
LALRGDGQKTDHVFKPNPDGHSNANELVEQIVNLRSGKYLEEDLRNSAPLDFCIGVAGYP
EKHFEAPNFETDLENLKRKVDAGADYIVTQMFFDNQKYYDFVARCRAIGITVPIIPGIKP
INLKNQLTVLPKIFNIDIPVELANELAKCKDDAAAKQVGTEWAIQQSKDLIANKISSLHI
YTYGVSDNTRKIVEAVF
>Q9Z675|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymomonas mobilis|TrEMBL
MERILRENPNFVAEPFLGEKEPHISFEFFPPKNEEADKLLWQSVERLAPLKPRFMSVTYG
AGGSTRERTRATVTRIARETTIPAVAHLTCVNASRDEIDDIARDYWDAGIRHIVALRGDP
PGGERFQARPDGYANAVELVEGLKRIAPFEISVACYPETHPQALSPEADIEFLKRKFDAG
ATRAI
>A0A659S524|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Poona|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGLRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVGIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2G6IZ59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium|TrEMBL
MASDRRGSAPRVSFEFFPPQSLDASFRLWDTVRALAPLNPEFVSVTYGAGGTTRDLTHDA
VAIIHKNYGVKVAAHLTCVSSTRDEVLQIADGYAEVGVTDIVALRGDAPKGLERFTAHED
GFANSIELVETLAQTGKFNIRVGAYPEPHPDSPDTAADVNWLKRKVDAGASSAITQFFFE
ADTFFRFRDACEKAGIDVPIIPGIMPITSWNGIKRFASGCGASIPVWMHDAYEKAIRDDR
SELLSTAICTELCSDLLEGGVEDLHFYTLNRPALTRDVCHALGVLPEKALLEVA
>A0A3S1N9K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M4A.F.Ca.ET.050.02.1.1|TrEMBL
MTIRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A7X0RPA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella nanjingensis|TrEMBL
MKPDLRAALAERALVGDGAMGTYLYQLGFPIGVSFEEYNLLQPDVIADVHRRYIAAGAEV
IETNTFSAQHGKLAKYGLEKKAEQINAAGVALARKAAGDRAYVVGAIGAIRAGRRKNVRT
ANIRRDFEEQAGALIGAGPDGLLLETFFDLEELSLALGIIRKLSDIPVICQFAVEDPTRT
HDGVPLPEAFARLAAEGADVIGFNCRSGPNGILRALEAIPRDFGLPLSAFPNAGLPDYVD
GQVVYSATPEYMGANARRFADLGARLIGGCCGTTPAHIAAIAGALRGYAPDAQAGAEASQ
SSPAARAQPAEPAPIPAKAAVSPSIVELVRQRHTVIVELDPPRELDIAKFMAGAAALKDA
QADALTMADNSLAVTRMSNMALAALVQERVGIRPLVHLACRDRNLIGTQSHLMGFDALGI
DHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKAGFVVGAAF
NPNVKYLDKAVQRLERKIASGADYVMTQPVYDAALIERIAEATRHLAVPVFLGIFPLASG
RNAEYLHNEVPGIQLSDEVRRRMSGLEGPAGRAEGVAIAKELLDSAMAHFNGIYLMTPFL
FYDMTAELTRYVKAQSKITREDGQTSCPPGGFQVE
>A0A2B0SDB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia megaterium|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINVAGVKLAKQAAKDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLNEGVDGLLFETYYDFEELKTVLTLARKETDKPIITHVSLHDIGVLQDGR
PLADALKELEDLGADVVGLNCRLGPYHMIQSLEEVPLPDRAFLSAYPNASLPAYVEGKLE
YETNEDYFVESARLFREQGVRLIGGCCGTTPAHVRAMSSALKDLPPITSKVVKMRPAVTV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRIRGEVEGLAIAKNLIDTAYELFDGIYLITPFMRYEMTEILTRYI
HDKQLVTSERKI
>A0A8J4I9T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spheniscus mendiculus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKHLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPVVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6I1L970|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMTVAKQLARYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPSAPHLSCVGDSKDELRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNAESYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISQMCEQLLQGGAPGLHFYTLNQAEPSLAIWDNLKLPR
>A0A420Z6L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesebacteria bacterium|TrEMBL
MSRLKENLAKGNFVVTSEIGPPKGTDIEKHLAKAEQIKEKVVAVNVTDLQSAVMRAGSLA
TCHLLHTRGIEPVYQLTCRDRNRLALQSDLLSAWILGIENVLCLTGDHPALGDHPEAKPV
FDFDSVQLLQASSTLNSGKDFSGHTLEGSPNFFLGAVVSPGADPLEPQIIKMEKKVKAGA
KFFQTQAVYDTEIFGEFVDKVNNLQVPIIAGIVILKSAEMAKFMNENISGVTIPDGLIEE
MDKTEKPDLKNKAVEIAARLIRQVKPFCQGVHLMTLGWEDLIPKIIEEANIGN
>A0A1H7V7W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. ob235|TrEMBL
MGSIKDLYGKGKTVLSCEIYPPKKEDEFKNIYTKLEQLSEIKPDFVSVTYGAGGSNAGKA
VEIADYAKNKAGLEVVSHITSVGFSKEKLEEGLNRFKDIGIENILVLRGDRPKLMTDEQF
NTRDFLHASDMAEYIKGKGMDFTLLGACYPHKHPEAKSEEEDINNTKTKVDKGCDVLISQ
LFFENDYFYRLIDKLHNLGVKAPISAGIMPITSAKQLGTTVTLSGTTVPEELSSIISKYG
DNPEEMKKYGIDYAIKQALELKNRGVDGIHFYIMNKPDLAKILMDAVR
>A0A1U8Z0W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. aurantifolii|TrEMBL
MIPTDTPSGASTITDAYSLEVSVKDIGALTNAAPGILPGCAMFIPYLPGQTEAARLAAAQ
MVRRLGFEPVPHLSARRIGSLEELQAFIARLVGEADVTGCLVIAGDPSTPKGPFADSVSL
IETGVFERSGIRTIGVAGHPEGHPIMRTTEQWDVLQRKCRSIQERGMAPLIVTQFGFDAD
IVMTWLEALRARGMTHPVRVGVPGPASVGTLARYAASCGVGACASVLSNYGVSIGKLFGN
AGPDRFVDHLVGRLTEAHGDVRLHLYPFGGIAQSVEWVAHYRSCKASQDRVSSVAAD
>A0A2M8UQ57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSQKERRFSFEFFPAKTEAGHEKLLATARQLAAKKPDFFSCTYGAGGSTRDRTLTTVLQL
DGDVQVPTAPHLSCVGDTKAELSALLAHYKDAGIRRIVALRGDLPSGMGMASGELRFANE
LVEFIRAETGDHFHIEVAAYPEVHPQARNFEDDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAEKLGVSIPVVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDIASIQAF
GEQVITDMCERLLEGGAPGLHFYTLNQAEPSLALWNNLKLPR
>A0A1I8FQ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
KSFAWPNFLNYKCQSVSQEILNPKQYTFLENSAPCQKTRAPLPRCRLKRSSSRRSRSGPQ
PPTSRQYRPLATRIRRRIEKGRRWFSCEFFPPRTPGGRCEPRLQVRQLRQGPAAVLRRHL
APGRNPAGDSPTSSTSVASAMLNYCGHRHRAAPDLRRPDRGSAGARAGSRKVARTQKHPG
AARGDLPEDADGNPGGASAAAIGGPAFASDLVRLIRRRYGSFFCIGVAGLPGGPPEGRQL
REDLRRLKEKVDAGGEFIITQLFFESADFLRFVSDCRRGYQSLRHIVKLSKLTVPDSMLR
VIEPIRDNDEAIRNYGIAQCTQMCQELLQSGQVHGIHFYTLNRDAATIRILKNIGLWRED
LPRPLPWQPSANYERCAEAVRPCSGPGGPPATCTGPGTGMTIPTAGGAPIRASKQERLRM
WGSEPTSEPDIWRVCSPATCPGNQSARTVSESPGCPGATKEPLPSSSESSEAAKARQRLA
GLSERGLLATNTCCGSTTRLHGWGGSGGFVYQRAYLEFFLPGCRLPALQVSRGIGTEQPR
WRRVSFHIADRSGNVNLCELLGAHRPHLGRLPRLGGRSAHLGRLYEEGSPSRRLIESVAE
TYLLVALVDNDFTEDSVLWDLTDQVARRPTARTRWSSLRKLQCRVSPRGLPRATVRPGTP
RGDHLRGFAVEVCAAPEAEGGWPDFDCATGLFAEMFNGE
>A0A231V2X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Notoacmeibacter marinus|TrEMBL
METMMAMPHTPLRESTDRAPVIRLDGANDADVKVSYEFFPAKTEKAEAALWDAVKRLEIL
QPSYVSVTYGAGGTTQERTLGTVARMVRETSLTPAAHLTCVGASCATIDAVADELWEAGV
RSIVALRGDPQSGFGGRYEPHPEGYPYAPELIEGLKKRHDFEVFCSAYPERHPESPDWQT
ELDVLRRKADAGASKAITQFFFEADIFFRFRDRVADAGIDIDIVPGVMLQPNVEGLSRMA
NAVGVAVPDWYRRLFEGLEDDLPTRQMLTASVATDLCAELYDGGVRDFHLYTLNRADIAI
AVSRALGEAHARIRHRE
>X0APU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. melonis 26406|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDRIKAIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDPVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A348SGG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MTASNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDTKAELRELLNLYKEAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRELGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQA
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A5N9C133|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MDSSGISDISFNIISDFSPEKSSKSEHYDLNADLVLVASNPGQSTRIESSSRASYMQATT
SADCLATLTLRDLSPLAIESMVLGLMMWEVKGVVIVAGDPPLEVPCKGLTQDWPKRTTQQ
IRSLQKLILDHKNPANPFVLGSVVDLGQSIDKAADLAGLKVKSGAEFFITQPIFSEGPAF
DFETLLMERLGDMEKPSIYYGLQLLEQESLCFSIIPDRVKEEVEQETNNLDSLTALAKKL
IASGQKQFYTIPPIFSGGERNYQLCRDFNLLLKKLIMAPKGQERTDSHL
>A0A0E3S077|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina lacustris Z-7289|TrEMBL
MHFNFREKLNSRKFLVTVEVSPPKGTRFSAPVEDVSQLKGVADALNVTDNQCSIMHMSSL
AFSKLLLDQGHEPVMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDYPTCGDHPGSKP
VYDLDSVQLIELVRKLDSGIDLAGKKLDGGTSFCAGAVSGIDPENTMQLIKLEKKVRCGA
EFIQTQAVYDVGMFEEFMEAVNHLEVPIIAGLIPLKSLVMAEYMNKNISGIHVPEETMLR
MKDAVSPIEEGLSIASETIKELIKLSRGIHIMPIGSHKNTPKLLSMAGISEK
>A0A8F6BDI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. AHE13PA|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVD
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VVALRGDARKDESYFKATQGGNAFASDLVQQISDLNKGKYLHDDIKVEHNYDFCVGVAGY
PEKHMESPSLNTDLKRLKQKVDAGADYVVTQMFFDNNKYFEFVKKAREIGITVPIIPGIK
PLAVKRHLQILPQVFKIDLPEDLIDAVEGCKDNKAVRQVGIEFAIQQSKELKEAGVPFLH
YYSMGKSDNIHAIASKLF
>A0A0K1E5C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chondromyces crocatus|TrEMBL
MHRMTPQRPAVPFLEALQRSILVFDGAMGSLLYERGVFVTQNFEQLNVTRPDLVKKVHDE
YVAAGAQVIETNTFGGNSFRLERYGLVDEVRSYNLAGAKLAREAAGEVAYVAGSIGPTGL
VPGVASQADLRDAAATFTEQAGALVEGGADLLIVETFRHMEELRIAINAARAAAPSTPIL
ASVTFDASGTVADGTPPERVASLLRDWGVDTLGVNCGDGPQLSLSMAERMRGVDLPLCAQ
PNAGLPRTVDGRLLYMATPEYFDVFTRRIIQAGARMVGGCCGTTPEHIRWMVKSARMLGG
GVSPVVATRPQAVPLEVHGLDPVPLDQRSRLSAKIAAKQFVVSVEVNPSPGLSPDSALAA
AKMLIDNGVDVVNVADGPRATARMSNLAFCSLLIQRYGIEPILHVCGRDRNLIGQMAHLL
GASAIGIQNLVVITGDPPKIGDYPEATAVYDLDSIGLLTMASTMNRGLDPAGKRIAGGQT
SFLLATGLEPGAQDLDREIRRLEQKRAAGAEIVMTQPIFQQELLDDVLKRIAHLEMPVLI
GVLPLVSYKNAEFLHNEVPGMQIPENIRERMRRAPPGAEARKEGVRIAREMLFSVRDKVQ
GAYLMPPLGKYELALEVLDGLK
>A0A385DI97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces koyangensis|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSEDWETDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A0A1ULX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani AG-3 Rhs1AP|TrEMBL
MKLTEKLATYRSDTPYFTFEFFPPRTDQGYSNLLTRISGLASLKPVATSVTWGAGGSTRD
RSLDLAGFCQADNDLDTILHLTCTNMEKGTIDEALMTAMERGVSTVLALRGDPPRGEEYW
IPTDPRFQHAEDLVTYIKQHPTFASRFCVGVAGYPDGHSEGGSEEEQLTHLKRKVDAGAE
FIITQLFYDVEKFKSWLRKVRSTGITVPVIPGVMPLQTYATFTRMTDLCKATVPLHIQAN
LDAIKHDDQLVKEYGVSLAVSMIRSILVDGDVKGVHFCTLNLEKSVRKILDELGWTHESL
HHNQIIIDANQSPHILPSPADAPHPTTFTISPSEAAQHANTSLAEHTRTGTLRTAAEAID
SGWDDFPNGRFGDSKSPAFGLIDPWDGGGLGVPPHVAIAQWGRPTTEQELSDLFLAYLND
TTSTTPFSPEPLSDESATILPHLVSLTKKGLWTVASQPAVDGALSSDPVIGWGPRDGRVF
QKSFVEFFATEADLEKVAQAIEDSGDGWLTFFAGNNEDGFLTNIPDSGSNAVTWGVFPGK
EIAQPTIIDRDSFLAWKDDAFMIWHDFGLCYPPDSPTRKLLEDVINTRWLVNIIHHDYKN
SNALWDFLAKYLE
>A0A5C1DC13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium paludis|TrEMBL
MTQTPRTFSFEFFPPKTPEGIAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGQAAAPHLSCIGSTRENIAAILNEYRSNGIRHLVALRGDIPSGMVAAGEFRYANELV
AFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLNNFVRKVRAGADSAMTQYFFNADSYFRF
VDEARARGVDIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRLRMQAYYDDTASIRALGL
DVVTELCDRLLQGGAPGLHFYTLNQAGLVSTIWQRLGL
>B9JY78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium vitis (strain S4 / ATCC BAA-846)|TrEMBL
MAHTSSKRDQARPFKLSFEFFPPKSEEMEAQLWATVDELTGWAPEFVSVTYGAGGTTKAP
TLAAVRRLLAETPLATASHLTCVGATREEIAQVVEDFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGFENAAALVKGLKELGDFEISVSAYPEKHPESADLAMDLDMLKRKVDNGATRALT
QFFFDNDIFERYLDKVRAAGISIPIVPGIMPILNLTQLKRFAGMCGTSVPAMLDQRFEGL
DDKPTERASVAAALAAEQIADLQARGIDEFHIYTMNRAPLVNATLERLGLQRSDTAAADR
AGVVA
>A0A1J0LJG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium UJ101|TrEMBL
MKITQHIKNANETLFSFEILPPKKGENIQKLFQNIDPLMEFKPPFIDVTYHREELVLKQT
KSGLKKFSVRKRPGTVGICASLMNKYNVDAVPHVICGGFTKNQTEEALIDFDFLGIDNVL
VLRGDPIKGESTFVSNKEGHSHATDLLKQINKLNKGVYLDSDQTDNAPTDFCMGVAGYPE
KHFEAPNLEEDLKYLKQKVELGADYIVTQMFFDNQKYFDFVKLCRENGITVPIIPGIKPI
AIQRHLTILPQFFHLNLPQELVDEVKKCKNNQEVRHVGEQWAIQQCKELMEFGVPVLHFY
SMGKSDNIYNIAKELF
>A0A5N9A6E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MKIFEILKKTRPISYEFSPPRTADGIPAVLEALDELKVYSPDFVSVTYGAGGSTRAFTEE
ITVQAKKVAGVEVMAHLTCVGQTKEEIHGVLERLDAAGVENVIALRGDPPRGETEFVPVA
GGFPHATDLLSHIKANFKFGVAAACYPEGHTESVDLDADLDYIKLKVEKGADFLVTQLFY
DNRYYFDFVERAKAAGIDVPIVPGVLPVLSSAQVRRFTTLCGSTIPSDLGKLLDKYADDD
SSARDMGVEYATAQVRELWDQGVPGVHFYVLNRSYSVSRILDNLALPGHQRED
>A0A3N4W4B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vulcaniibacterium tengchongense|TrEMBL
MPRVPISFEFYPPKTEEQRAQLDKTAARLKPRRPEYVSCTFGAGGSTLSYTPETVGHLHR
AHGFDAAPHLSCVGGTRAELAELLRRYRAMGCRRIVALRGDLPSGMGHTGDFRYASELVE
FIRREHDGHFHIEVGCYPECHPQADDALADLRHFKAKVDAGADGAITQYFYNADAYFRFV
DDARRLGVAVPIVPGIMPIANFTQLRRFSETCGAEIPRWIGKRMQAFGDDAGAIREFAAD
LVANLCQRLIDGGAPALHFYTLNLSRPTLAVLARLD
>A0A7X8V9Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacteraceae bacterium|TrEMBL
MNLKEKIERGDFVITAEMAPPKGIDFSHIRECARAVKGRVDAVNVTDFQSAVVRASSLGG
AKILLDEGLEPIMQITGRDRNRIAIQGELLSAAALGIKNVLALTGDHPSIGDHPEARGVF
DMDSVNILQTATKLMSGRDMNEHELSGIPQFFLGASVTPLYDPLELQIIKMKKKIQAGAK
FFQTQAVYDINVIKGFMEKMKNINAKVLVGVIPLKSAGMAKYMNNNVPGIHVPDEIIDRM
KKAEDKTREGLTIAAEFIQQIKEEKICDGVHIMAVGAEENVPILLDMCGF
>A0A8E2JKQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lepidopterella palustris CBS 459.81|TrEMBL
MHISQKLEQSRRENRPTFSFEFFPPKTAQGVQNLYDRMDRMHAFGPTFVDITWGAGGRLS
HLTCEMVKVAQSVYGLETCMHLTCTDMGKSKIDEALREAYKSGCTNILALRGDPPREKEK
WEATAGGFRYAKDLVKYIRDTYGNHFDIGVAGYAEGCEDQDDPDLLIDHLKEKVDAGGTF
IVTQMFYDVDIFLDWVNKVRAKGITAPIIPGIMPIHTHAAFIRRATWTKCNIPPAWTKAL
EPIKNDDVEVREVGKDLVAEMCRKLLNAGILHLHFYTMNLAQATRMVLEELGLLPDMEAP
LEKPLPWRPSLGLNRREENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDARSPAFGELDA
YGVGLKGTNEQNIKLWGRPISVKDIAELFVRYMNGKLDSLPWSEAPISKEAESIQDDLVD
LNRRGFLTINSQPAVDGAKSSHPVYGWGPRNGYVYQKAYLEVLISPEYIAEVITRIERDP
DITYYAVNKAGELKTNAPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFFRLGQDW
ANCYSSASPSRYVIEDLMDTWYLVNIVHNDFHVPHGIFPLFNELQVQDLDKPLHTNGILN
GDGPSNGDQSNGTDHSITNGVSGLDLKS
>A0A0E3ZCP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter korlensis|TrEMBL
MKVTDHFNNANGKTLFTFEILPPLKGENMKTLFNHIDPLMEFNPPFIDVTYHREEYVYKQ
RENGLLEKRSTRKRPGTVGICAAIQNNYKVDTVPHLICGGFNKEETENALIDLHFLGIDN
VLVLRGDCVKSEQRFVAEAGGHNYASELIEQVVDMNNGRYLDDEQLNNNGTDFCIGVAGY
PEKHFEAPNLRSDLRWLKKKIELGANYIVTQMFFDNQKYFDFVKLCREEGIDVPIIPGLK
PLTTKTQLSLLPSLFHIDIPCDLADAVEACADNKAAAEVGVEWAIQQSKELMEFGVPCLH
YYSMGKSGSVRKVAEALF
>A0A150L6Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parageobacillus caldoxylosilyticus|TrEMBL
MKQGLLDYIQGNLLIGDGAMGTLLYSQGIPIGSCVEWLNLKNPEMIRDIHLSYRRAGANL
IETNTYGANAEKLSKFGLQDKVDEINRAAVMIAREAAGNDTFVVGAVGGIMGEIKKDINR
KKLEMVYGQQIDSLVAAGIDGLMLETFCSVDEALLAISLARKYQDLPIVCQLTVQDIHRT
QDGYLLEDAFLQLYHAGAHIVGLNCYNGPANLIRSLETIPLDKGFILSAYPNAGIPSYED
GKYIYSPSPDYFGWAAKTLYELGVRIIGGCCGTTPEHIAAVSAALKGKTPITKRAVSGIE
EKQEKETIHISGPPQQKTLPELVREKTTIIVELDPPRDLDYLPFLEGAKALKEAGADAIT
LADNSLAITRMSNMALGRLVKEQEGIRPLLHLTCRDRNLIGQQAHLMGLYALGIDHVLVI
TGDPSRYGDLPGASSVYDVSSIEMIRMIKKLNQGISFSGRPLKNRSSFTVGAAFNPNTRH
LQKAVERLEKKIEAGADFIMTQPLFCREQIEQVAKATQHLSVPIFVGIMPLTNHRNAEFL
HNEVPGIRIPDDVRARMNGYKGEDARKQGMEIAKELADKVLEYFQGIYLITPFMRYEMTT
ELTRYVRNRNSLS
>A0A0D6ZBZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesobacillus subterraneus|TrEMBL
MSFLKRMENEILIADGAIGTLLHSYGAGTCFEELNLSQPEAIIKIHKAYMDAGADLIQTN
SYAANYIKLERYGLEDQVKEINSAAVRLARQAAGSEAYVLGTMGGNRGIRPSAIPIEEIK
RSFREQLYCLLLEGVDGVLLETFYDMEEIETVLAIARKETDLPIIAHVTLQEIGIMQDQT
PLQEVFNRLENLGADIVGLNCRLGPHHMISSLEQIKLPTRAFLSVYPNAGLPAYTDGKFH
YEGDPEYFRKSARSFREQGIRLIGGCCGTTPEHIKALADELKGSQPVSNKLVAAKKVKVV
AAPADVKRPDAPLHELVKERPSVIVELDSPRKLDTKRFFEGAKALKEIGIDALTLADNSL
ASPRISNSAVGHLVKDKIGMRPLVHLTCRDRNIIGLQSHLMGLHTLGLHDVLAVTGDPAR
VGDFPGASSVFDVSSFELIEMIKQLNSGLSYSGKDLGQKGAFSIGAAFNPNVRSIDKAVL
RMEKKIRAGADYFITQPVYSEKMLLAVQEATKHLDTPIYIGLMPLTSSRNAEFLHNEVPG
IKISQEILETMAKFNNEPLQSKKEGIAITKGLIEAAAELFNGIYLITPFMNYEMSVELAR
YAKEYSSHLQRRKQNVNLVN
>H0BCM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. W007|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVRA
TQQIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A5F2I4X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1D.F.Ca.ET.183.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAPRDQVDAVIREFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A1C5H699|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora echinaurantiaca|TrEMBL
MALGLPSVLPQSQPAIGELIRDRQPTFSFEFFPPKTEQGERLLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPEGVLYAEELVRLVRESGDFSVGVAAFPYKHPRSPDVASDTEHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQMSTIERSVQLSGAPF
PPALAERFERVADDPEAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLQ
VGARV
>A0A1G8VC08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium muleiense|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVCG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A2R7KBP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. HMWF030|TrEMBL
MKVTEHIENAKGKTLFSFELIPPQKGKSIQELYDNIDPLMEFQPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGITN
VMALRGDAMKDEQSFVPKVGGNKFAIDLVRQINDLNCGKYLHEVMDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFNFVEKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNADIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A516P181|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. SNU WT5|TrEMBL
MKITDHIINANGKTLFSIEIVPPTKGTGIEDLYKNIDPLMEFKPPFIDVTTSREEFIYLD
KGNGLMERKTTRMRPGTLGICAAIQHKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGIEN
IMALRGDAMKGQQYFEATEGGHKNAMDLVHQINDLGRGKYLHEEKDCDEYNKFCIGVAGY
PEKHIEAPSMNYDLKWLKEKVDNGADYIVTQMFFENKKFVEFVKSAREIGITVPIIPGIK
PIATKKQLQLLPQVFKIDLPEDLISAVENAKDNAAVKQIGVEWAINQCRELLDFGVPVLH
FYSMGKSDNIKKIARELF
>A0A0S8HMG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium SM23_33|TrEMBL
MNEPVSKLQEILDAGQFAVTGEIGPPKGTNVEPALHEAQQYLEGRVAAVNVTDIQTAVMR
LGSMAVCHLLLDRGVEPVFQMVCRDRNRLALESDLLSAYTLGIRNVLALTGDHVAMGDHR
EAKCVFDLDSVGLLEAMARLEAGTDLGRDAKGNPNQLDGVPKFFKGCCVTPCADEVEPQI
IKLEKKATAGAQFVQTQAVYDPAAFEKFMNQIQHVKVPVLVGIVLLKSAGMAKYMNRSVP
GVQVPDAIVQRLTDAPKEDRAKVSVEIAAELIRAMKPMCQGAHLMTLGWDHCVPDIIQQA
ELA
>A0A831J9H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter sp|TrEMBL
MLKNENLCTKLKKRKFVVTAEISTPKGVDITKTIEEARKLKGIVDALNITDCPMANMRMS
PIAVAHLLQDHLNIEAIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDEPSRGDTPQ
AKGVYDVDSVGLLKIISAFNRGYDYNGNKLDSPTEFCAGTTANPNDLRDEALEKLKVKIE
AGAEFIQTQPVYDEEILFKFIEKIKNFNVPLLIGILPLKSYKMAVNLNEKVPGIDIPEKV
LERLKDGGREEGINIAVEFIKRIRSEVAGIHIMPLGSTNVVLEIISRVDDLVCDFAENNV
QMN
>A0A6A4QTG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lupinus albus|TrEMBL
MKVIEKIRAASSDPDRVVFSFEFFPPKTEDGVDNLFERMDRMVSHNPSFCDITWGAGGTT
ADLTLEISNKMQNMICVETMMHLTCTNMPVDKIDHALQTIKSNGIQNVLALRGDPPHGQD
KFVQAEGGFACARDLVKHIREKYGDYFGITVAGYPEAHPDVIASDGLAPPEGYQNDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KVPADIMAALEPIKDNEEAVKAYGIHQGTEMCRKILSHGIKNLHLYTLNMEKSALGILMN
LGLIEESKIYRSLPWRRPTNVFRIREDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSDS
PSYGALTDYQFMRPRARDKKLVEEWAIPLKSIEDIYERFKLYCLGKLRSSPWSELDGLQP
ETKVINEQLEKLNTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKL
DALVIKSKDRSSLTYMAVNKEGSWKSNVGPTEVNAVTWGVFPTKEIIQPTIVDPVSFKVW
KDEAFEIWSRGWAALYPEGDISRKLVEEVGGSYFLVSLVENDYVNGDLFGVFADF
>A0A7W7XZ03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rehaibacterium terrae|TrEMBL
MTPISFEFFPPKTDEQREQLDRTAGKLRRHDPSFVSVTFGAGGSTLSYTPETVRRLRERF
VLDAAPHVSCMGGSREEIRKLLKLYRALGCRRILALRGDLPSGMARSGDFRFAAELVEFI
RAEHGDWFRIEVACYPEMHPQAEDAFADLRHFKAKMDAGADAAITQYFYNADAYFRFVEA
ARAIGVTQPIVPGIMPISNFGQIRRFSEQCGAEIPRWFLKRMQAYGDDVDSIRDFAADFV
ADLCRRLVDGGAPELHFYTLNLARPTQAVLARLG
>A0A1J6XAJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. AR7-10|TrEMBL
MSSIPFSFELYPPRTAESTRALHDTIDRLAEAGPDFISVTYGAGGATGGRSLEVLRYIRA
HTDTEPLAHLTCVGNTYAGAARLIREFLDAGVLSFLALRGDPPAGQSEDDVFLGDLESSA
QLVQLIDRVQAERAPYEESPVRGNPGAVRVAPRRRVNIAVAAFPNGHPRSAYSSQHVDAL
LAKQAAGATVAITQLFFHPDHYLAFVERARRAGVAIPILPGIMPITSPARLARVLELTGE
ELPSELAIELEVEPTTEGRRRIGIRWAADLIRAVVDGGAPGVHLYAFNQHETVLDVLRLA
GIIPQRQLSAASKGTP
>A0A358J1Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRNAVNVSFEFFPPKTDAAEANLWSAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIEGYKAIGVDH
IVALRGDPPGSSGIGGAYTPRADGYANATELTAALNRIGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLKRMT
AACGAALPDWLAGHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAAA
>A0A370JZ50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meiothermus sp. QL-1|TrEMBL
MRISEILRQNRPIFSFEFFPPKTPEGEALLFRTLHELKPLRPAFVSITYGAGGSERRKTA
LWAKRIQEEVGLTAMAHLTCVGHTREELKAILEEYRAAGIENVMALRGDPPRGAAVFQPV
EGGFRYAAELVAFIRAEFGGAFDLAGGAYPEGHPEAVSLEADLHHLKAKVEAGLDFLVTQ
LFFNNALYFGFLERARRVGIGVPILPGLMPITDLAQIRRFMDLCGASIPGPLLSRLERAR
SPEEVLEIGVEHTTRQAQELLAAGVPGLHLYTLNKSPATRRVVENLQTVLR
>A0A4R9BXE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Sr59|TrEMBL
MTATPASAPTDPPCPPSTPFSFELYPPKSDAAASALHTTIDALAAAGPDFISVTYGASGS
SRTSSLDVLRYIRQATRVDPMAHLTCVGSSHAEASSLIREFLDAGVQSFLALRGDPPEGL
TEGDTFLGDLHSAGELVQLIHRVQAERVPYRETPIPGLPRARAVKTERQHVRIAVAAFPN
GHPRSRSTAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPV
TSPGRLRRILELSGEELPSELAIQLEVEPTAEGQREIGIDHAVTLARKLIAGGAPGLHLY
AFNQHETVLTVLDRAGALAPGRSATAAPTSSMPRPSDVHAGIHSTKDY
>A0A2E2D851|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp|TrEMBL
MAKNLTLSCEFFPPKTEKGIANLSSVREQLAPLKPEFFSVTFGAGGSTQDNTMDAVIDIQ
KQHAVTNIDAAPHLSCVGSSAERIRALLDTYRNNNIHRIVALRGDLPSGMQAPGDFRYAS
ELVEFIRKETGDFFTIEVAAYPEVHPQAQSAEHDLINFKRKVDAGANSAITQYFYNIDAY
RYFVDACEQQGIDIPIIPGIMPINNYAQLARFSAGCGAEIPRWLRKKLEAFYDDTASMTA
FTVDFLTDFTQQLIDLGVPGIHFYTMNKVDPTLTICDRLGLIK
>A0A3B9EEH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRNAVNVSFEFFPPKTDAAETNLWSAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIEGYKAIGVDH
IVALRGDPPGSAGIGGAYTPRADGYANATELTAAIGRVGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRTAGVTIPLIPGVMPVSNFAGLKRMT
AACGAALPDWLAAHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAVA
>A0A7X5UZF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas leidyi|TrEMBL
MTILDPLAAPLFADVAGDIDVSFEFFPPKTEKMEETLWESIETLGPLGPRFVSVTYGAGG
STRERTHNTVARIARETAIPAAAHLTCVEATREEIDQVAREYWAAGVRHIVALRGDPPRA
GEKYGTHPGGYENAADLVAGLRRLHPFEISVAAYPECHPDSPNQAADLDNLKRKIDAGAT
RAITQFFFEPETFLRFRDDAAKAGIDAEIVPGIMPVMSFASVVRMAGMCGTQVPGWMERL
FEGLDEHPAARQLVAATLAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGVRPKVAA
LAAA
>A0A7C4RT92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatirhabdium butyrativorans|TrEMBL
MKITHLFEQGIFVVTSEVGPIKGAVSRDKTIHPTCAKEAMFLQHHVHAVNVTDNQSAVMR
LGSLAASVLLKEKGIEPIYQLTCRDRNRIALQSDLLTAFSLGIDNVLLLTGDHIQLGDHK
EAKPVFDLDSVQLLHMAMGLRNGYDITGHPIENPPDMAYGAVVNPNFEPIDLQLIKMRKK
VDAGAEFFQTQAVYDEAVFDRFIDKASAMGCPIQLGVVVLKSPQMGEYMNANVSGITVPK
SWIDEIGSVDKADRKKKAAEMTARLIRKLKGRVQGVHIMPLGWTDVVPDILAQAEIEVQR
LAVAA
>A0A6B8RNQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus psychroresistens|TrEMBL
MNPDEKLDLRDALKQRIIIGDGAMGTYLYQLGHPIGVSYEEFNLLKPANIMEVHRLYYEA
GARLIETNTFSANREKLSRYGLENDVVAINQAGVRLARQAVGADAYVVGAVGSVRSGRQT
NITTVQVDYDLQQQIEALLSAEADGILLETFSDFSEIKSALAIIRKISDVPVICQFATED
SGLTRDGIPFVEAFQQLQANGASVVGFNCHSGPNGILRALEKITPFVNGPYSVFSNAGLP
GYVDGRYMYRATPQYFAETALQFADLGARIIGGCCGTTPEHVAAMAKALELYIPSTDTTP
KSQVIVINEHKVVEAKPEVELPVAEPSILELVKKRHTVIVEWDSPRDLAIEKFMKGSQAL
KDVGADAITLADNSLAQTRISNMSMGHLIKDRIGARPLLHVACRDRNLIGTQSHLMGLHA
LGINHILAITGDPARVGDLPGSSSVYDLTSFDLIRMTKQLNEGIAFSGKLLKQKSNFIVG
AAFDPNIKHLDKGIQRMEKKVAAGADYFMTQPIFDVTQIEKFYLASKHIDIPIFLGIMPL
VSGRNAEFLHNEVPGIRISDDIRKRMAGLEGEAGRRMGVIIAKELVDAAMQYFNGIYLMT
TMTFYEMTVELTQYIWKKSNRVDLPLYPPAK
>A0A7C4RTU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatirhabdium butyrativorans|TrEMBL
MTTKTPSKLEKILASGQLAVTSEVGPPRGSDPKHIEEKANLIRNHVDAINITDNQTSVTR
LCSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAASFDIYNILCLSGDHQSFGDCA
QGQNVHDIDSMQLIQTVRHMRDEGKFLGGADIDRPPRMFVGAAANPFADPFEIRVMRLAK
KVAAGAEFIQTQCIYNLDKFERWVQMARDRGLTENVHILAGVTPLKSAGMARYMKNRVPG
MDVPDEVVKRIAGVPKEKQPEEGIAICVETIERLKTVPGIHGFHIMAIEWEEKVPELVKG
AGLYPRPQV
>A0A7K0G4X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter petrophilus|TrEMBL
MKIIDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADQSFIPTKGGHCYATDLIQHIKNHNEGKFLHEDIETFKSDFCIGVAGYP
EKHFEAPNLNADFKYLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPEELTDALSHAKSNAEAKEIGTAAMIKQCKELMDFGAPVLHF
YTMGRPEQTKQIAKAIF
>A0A7Y2XP87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansiaceae bacterium|TrEMBL
MQQLRDILEDPSDNFPIGVELVSTRGTTEELKAVKARDFSMELAHTDAVDWVSITDNAGG
NPMLAPAALGKTLLEEQKPVAIHLSCKDFNRNGLESVAWQLNSEGFHNILALSGDSPIDG
HEGQAKPVFDIDSVGLLTMLSEMNQGMRVKGPGNKIRQLGVTRFFSGAVVNNFKCHENEV
VPQYLKLDKKIECGAKYIINQIGFDARKIHELLCYMRRRKNTHIPMVGNVYVLSGFVARL
FHSRKIPGVYVNDDLLALATEQSKSPDKGRAFFLEFAAKQLAIYRGLGYKAGYLGGVHSY
RAVQEILGIEKSFAADDWKQFAKELNFCHPQEFYMFDEDKETGLSTMDLEPDFAASLETR
PRKSASYTLSKVFHSLMFTKGKGIEPLCTRLVANSKDPDQGPWWMRKMEHVSKSILFSCR
DCGDCSLPETAFLCPESQCAKNQRNGPCGGTRDGLCEVNDNRCIWARAYDRLKCDGTQLD
LLAHDPTLQDQSLRYTSGWANCWLEKDHIAKKKELKQKQPTT
>F9ZJS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas sp. AL212|TrEMBL
MDSQKKFSPTFSFELFPPQTPQGIEKLRFTRQQLAQFNPKFFSVTFGAGGSTRERTFETV
LEIQSEKHVVAPHLSCIGSTQQNIRIILEKYYEIGIRRIVALRGDLPSGMAQAGEFRYAS
ELVAFIRKEFGSSFHIEVAAYPEYHPQARSAQADFENFKRKIETGANSAITQYFYNTEAY
FHFVDSCESAGLNIPIVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLEGYSDDSASIQA
FGLDVVTDLCERLLKAGAPGLHFYTLNSASLTSIIWQRLNLKEYVQ
>A0A2U2D7H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas prosekii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGNHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCDRLLHGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A2W4ZYG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas suwonensis|TrEMBL
MARVPISFEFFPPKTDEQRAQLDRTVERLKPHAPEFVSCTFGAGGSTLGPTGATVQRLQD
THGLEAVPHMTCVGGASAEIKVLLRRYRSQGHRRIVALRGDLPSGMGNVGELGHAADLVR
LIRSEHDDHFRIDVAAYPEMHPHASDAFADLRHFKAKVDAGADGAITQYFYNVDAYFRFV
DDVRRLGVTVPIVPGIMPISNYAQLRRFSESCGAEIPRWIDQRMRAHGDDVDAVREFAAD
LVVSLCWRLIQGGAPALHFFTLNLSRPTLMVLSRL
>A0A436ZWL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobotrys flagrans|TrEMBL
MHIKDKIAACEKAGKPCFSFEYYVPKTAQGVQNLYDRMERMGSFGPQFIDITWNAGGRLS
NLTTEMVNVAQTVYGLETCMHLTCTGMEKEKVDNALQEAYNGGCTNILALRGDPPRENEK
WSAVPGGFRYAKDLVKHIREKYGDYFDIGVAGYPEGCDDEVDPDVLLDHLKEKIDAGGTF
IITQMFYDVDIFLGWVNKVRAKGITVPIIPGIMPIHTYAAFIRRATWTKIHIPERWLEVL
EPVKNDDVAVRDIGRDLVVELCKKILAAGINQLHFYTMNLATATRMVLEGLDLMPSLEAP
ELPALPFKSSLGLGRREENVRPIFWKNRHKSYVARTQEWDEFPNGRWGDSRSPAFGELDT
YGIALKGTTEQNIKLWGRPETIADIADLFVRYMDGKLESLPWSDSPIDASADPIKAQLSE
LNKRGFLTTNSQCALNAVKSSHPIHGWGPKNGYVYQKMYVELLVSPDVLSELITRIERSS
DLTYYAVNKAGVLHHNAPAGGSPNAVTWGVFPGKEIVQPTIVELISFLAWKDELYRLGED
WAACYPQSSASRHIISSVMENWFLVNIVNNNFLDNDAIFELFKDLKIDNLNEKIPVDEYL
QNLKITDGIATNGTAHEITNGAPAA
>A0A4T0W2U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum higginsianum|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTAMGLSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKDE
YRDTEDSDVDDIEDFVWAVDLVKYIRKNYGDYFCIGVAAYPEGHADESHPQGQSFEHDLP
YLVEKVQAGADFIMTQLFFDIKAYDKFENILREHPSGAFKDIILLPGLMPIQSYQMIKRT
TKLSHAKIPDNLMARLDAAKGDDEKVKQVGVDILSELVEQVKEVKNRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDPQLDNEEAVIDDGPGVPVSIPAVQLNGLSPITPAARALSGRRH
SSMGSSDPHNRIIVSSASNPAYEMTTAGLMASEPVNTRANTLAISEGVGAVGREATWDDF
PNGRWGDARSPAYGEIDGYGVSLHMSVTQAIRLWGTPKTIQDINNIFIRHIKGQLNAIPW
SEEELLPESNMIQQELLELNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVEL
FIPSSDWAGLVARLNEVTDNTICFYAANAAGDFVSSDSSGGLVLEGTEASTNAVTWGVFP
GKEIITPTIIEEVSFRAWAEEAFKIWGEWSKVYGKGSESEALLERIRTEYWLVNIIHHDY
VERDALWKLLSGEKEN
>A0A0K6I4Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomonas bhubaneswarensis|TrEMBL
MRMDSKPPVSLSFEFFPPKTPEGADKLCAVRQRLYARRPEFCSVTFGAGGSTQEGTLQTV
REILAEGVDAAPHLSCIGASRDSVRGHLHAFQAAGVKRIVALRGDLPSGYGIGGEFHHAR
DLVAFIREETGSAFHIEVAAYPEMHPQARSPLDDLRHFADKVRAGANSAITQYFFSAAAY
RRFVDDVRALGLDVPVVPGIMPITNSSQLLRFSEVCGAEIPRWIRLRLQSYGDDRESIRA
FGREVVSSLCEELIASGAPGLHFYTLNQAEATLAVLDDLGR
>G0S5U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)|TrEMBL
MHIRDMLAEAERTGEPSFSFEYFPPKTAQGVQNLYDRMERMYNYGPKFIDITWGAGGRVA
ELTCEMVVQAQAYLGLETCMHLTCTDMGVERINDALRKAYKAGCTNILALRGDPPRDKEK
WEAAKDGFRYAKDLVAHIRKEYGDHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDMGAGF
IVTQMFYDVDNFLRWVKKVRERGISVPIVPGIMPIATYASFLRRANHMKCKIPEEWMAKL
EPVKNDDVAVREIGKTLVADMCRKILDAGIRHLHFYTMNLAQATRMVLEELNWLPSPDRP
LKHALPWKQSLGFGRRGEDVRPIFWRNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGVGLTGSNEQNRERWGEPKCIRDIANLFIRYLRKEIDYLPWSEAPVADEADLIKDELID
LNRRGLITVNSQPAVNGAKSNHPVHGWGPSNGYVYQKAYLEFFVSPELYPEIKRRIESHP
DLTYHAVTKSGNLETNAQSDGPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAYHLGMEW
ARCYDAGSPSRVLLEEMMNTWWLVNIVNNDFHQGNTLFEILKGLEVTDLDKVPETQANGT
NGVSNGVKASETSV
>A0A101FNK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistales bacterium 54_24|TrEMBL
MKIKGLFSHGRPVVSFEIFPPKRDLPIDSIYATIEELKSLQPDFISVTYGAGGSTKERTV
EIASSIRNVYGIRALAHLTCVGTSKEEADSILKELLSCGISDVLALRGDPPAGMDIDSVP
RHFRYAADLVAHIRRVYGDAFSIGGAAYPEGHVECDDIELRLLHLKAKVEMGVDFLITQL
FFENEAFYRFLEKARGIGINVPISAGIMPVVNKKQIERIVTLCGASIPPKLARILSKYAD
APEALEDAGVAYAVDQIVDLLSSGADGVHIYTMNRPWVARRIMESIARLLRELKKPKERA
EVS
>A0A2S7C2U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas dyei|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTATKLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAVDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ASLCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A4R5D093|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sandaracinum|TrEMBL
MKVTQHIEAAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKLGGNDFAVDLVKQINQLNCGKYLHEVMDVDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVEAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIKQIASKVF
>S9P093|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cystobacter fuscus DSM 2262|TrEMBL
MKIRNRLNPSNPCFSFEFFPPKTDAGTANLLQTLEDLAPLEPGFVSVTYGAGGSTRDRTV
DLVTRIKRDTGIEAMAHLACLGHTREELRELLRRLEAAKIDNVLVLRGDVPQGASADTLA
NTDFRHATDLVRFIREEDFDFSLGGACYPEGHVETRSRDEDLLHLKAKVDAGLDFVITQL
FFDNAFYFDFVERARRVGINVPIVPGIMPITNHEQIQRFTRLCGATIPMRLALQLEQLKD
QPEALVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRART
>A0A7W4H0I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus sp. MC1679|TrEMBL
MPVTETSLRSVGELIRAAHGPLYSFEFFPPRSEEEEPVLWAAVEALAPLEPSFVSVTYGA
NGSRRDRTIRATRRIAASGGPLTVGHLTCVAQSKAELAEALAEYREAGVTNILAIRGDMP
GGGPWTAHPDGLANATELVKFVKAEGDFCVGVAAFANPHETSNDPDLDAQILLDKVEAGA
EFAITQLFFEGERYGELVERMRGLGCEVPIIPGIMPLTVLSQIERFADLSGRELPASLVA
ELRACSSKEEVREAGLAAAVRLCRGLLDAGAPGLQFFTQNRSKATREVLAELKGTAPAP
>A0A841R7Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaeta isovalerica|TrEMBL
MLVKDILDKQKLTVSFEFFPPKNESGWDELFESISKLMPLKPSYVSVTYGAGGSTRDKTH
DLVTKLHNETDLCIVAHLTCVNSTRDEVKKIIERYNSQGIFNILALRGDLPRGVSEYNKD
GNGFDHAADLISFIKDISPGTGIGVAGFPEGHPQMPNRLKEIEYLKEKIDAGADYIVTQM
FFDNRDFYDFKERCHLAGINVPVIAGIMPITSRSGMNRMAELAAGARFPAPLLKAAGRAE
DEFVRRVGVQWATEQIRDLIDNDVDGIHLYTLNRSRSTIRICESLGITSYDKLY
>A0A8D3DTQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scophthalmus maximus|TrEMBL
NLNCNGSWSDSSGASNSGGESSKESSRSSTPVLDADRSDRLRDKMRRRMESADRWFSLEF
FPPRTTSGAVNLLSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLES
VLHLTCCNQTREIITGHLAKAKHLGLKNIMALRGDPVGADWEEEDGGFNYAIDLVKHIRS
EFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVITQLFFRSDTFLKFLDDCR
AIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITNVIEPIKDNDAAIRNYGIHQAVE
MCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRP
IFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLHMWGEE
LMKEESVFEVFTCYITAQPNCSGQKVMCLPWNDEPLAPETNLMKDELEKVNRRGVLTINS
QPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVH
GRNLTNALDFQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYEDESP
SRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIEDMFEMLDAPPEPV
>A0A2N0ZGV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus horneckiae|TrEMBL
MSFLKRMETEVLIADGAMGTLLYSYGTDSCFEELNLSAPSQIENIHRAYIQAGADLIQTN
TYAANYLKLKRYGLEDSVKEINSAGVKIARSVVQSGTYVLGTIGGIRGIKPLTISLEEIK
RSFREQLYCLLLAEVDGLLLETFYDLEELETVLMIARKETDLPIITQISLQEIGILQDQT
PIDESFLRLEEKGANIVGLNCRLGPHHMLETLSRVALPKHAYLSAYPNASLPAYIDGKIQ
YEDDENYFKKSARPFLEQGIRLIGGCCGTTPNHIKAFADEIRHAAPVLSKTVKQPSVKKA
VETITISRTEKPIQDLVKNNRAIIVELDPPKQLTTEKFFNGAKALKRAGIDALTLADNSL
ATPRIANEALAHLVNKKIGIRPLVHISCRDRNLIGLQSHLMGLHTLGLHDILAITGDPAR
VGNFPGASSVFDLSSFELIEMIKQFNDGLSPTGKELGQKAIFSVGAAFNPHVRYLEKAVA
RLEKKIQFGADYFISQPVFSEEQLINIHKKTKHLSVPIYIGIMPLISSKNAEYLHSEVPG
IKIADHIRQQMAAVSHDPIQAELEGLTIAKSLIDTAMDLFNGIYLVTPFLRYSLTAELTK
YIRQKDKQKESQYAEAEFQ
>A0A2T0BSV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium luticellarii|TrEMBL
MSLLEEAFKKGDFAITAEMAPPKGTDLSHLIECAKGVKGRVQGVNVTDFQSAMLKATSLA
TCKVLKDVGLEPVLQITGRDRNRIAIQGELLSAGVFGIENVLALTGDYTGIGDHPGAKPV
YDLDSVGILQVASTLASGKDMAGNDLNGVPEFYLGACVTPRYDPLDLQIMKMKKKIKAGA
KFFQTQGVYDIDTLKEFREKTKDLDAKIMVGIIPLKSAGMAKYMNKNVPGIYVPDELIDR
MKNAEDKVKEGIKISAEFIRRIKEEGLGEGVHIMAIGAEKNIPLILDEAGL
>A0A416IDE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM54-14XD|TrEMBL
MKIRDIIGQEKATLSFEVFPPKKDTDFASVEAAALGIAALRPSYMSVTYGAGGSTKGHTI
KLANEIQEKYGVPTIAHLTCVCANKDSIRTALSEMKNAGIENILALRGDIPKNYDGQVFT
DFAHASELVKLIKESGDFCVGGACYPEVHPDSANKQDDIANLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRIREAGIAVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEVAAGIQANLSDILLV
>A0A1E7Q4G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rheinheimera salexigens|TrEMBL
MAFANAQYLDAINRNLDQIQGKVNVSFEFFPPKTAAMEQTLWGSIERLAPLAPAFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASKEQLIEIAKDYWRNGIRHIVALRGD
LPPNSISKPALYATDLVEILRSVADFDISVAAYPEVHPEAPNAQFDLLNLKRKVDAGASR
AITQFFFDIEKFLRYRDRCAAIGIDVDIIPGILPVTNFQQLEKFARLTNVAVPNWMHKAY
QGLENDSQTRNLVAANMAMEMVKVLSREGVDHFHFYTLNRCELSYAICHLLGVRPPVAMA
V
>A0A2N6D992|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denitrovibrio sp|TrEMBL
MKISEILKSKRPVSFEFFPPKKQESEHVLFNTIKELRKYNPYFVSVTYGAGGSTADKTLE
WTKCMKQDYDYSVMMHLTCVGVGIDTIDDIIAKLTELKVDNILALRGDMPAEMSEGNICR
DFGFAGDLVKYIKLKAGEKFSIGVAGYPEKHPEAKSMADDIENLKRKIDEGADFVITQLF
FDNFHYYHYMDKVRAAGIDVPVIAGIMPIINISQAVKFTQMCGASIPKPLLAKMENMSAE
DQFKTGIEFASKQCGGLWASGVDGLHFYTLNKYGATEQILNNVF
>A7HMJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium nodosum (strain ATCC 35602 / DSM 5306 / Rt17-B1)|TrEMBL
MKIVEKLRNEKIVSIEIIPPKRGEDVEKIFATLDKLMDYNISFINITRHPSEIDYLETEN
GIIKVQKIKRPGTIGLTAALMKRYNIDVVPHLVCKGMNKFEMEDILIDLSIMGVENVFVV
RGEEVKSVAKSDYKYASDLVKQISDMNNGRYLYTEAKPTNFCIGVAGYPEKHFEAPNLDV
DLRFLKQKVDNGADFIITQMVFDAAIYEKFVEKSRSMGINIPIIPGVKPVVSKKSIYSIP
KKFFVNIPQKFVEKMEEAKSESEEFEIGVRFTVELIKNLLEKDAPGVHIFTMGRGEEVCK
VLKLLREGGILNV
>A0A562QQR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus nanhaiisediminis|TrEMBL
MSIYLGNEVDPTNHFTVTAELVPPRDWNPYPIIEQAASYRGLVDAVDISDNLLAVARMSP
TVCAFFIRQIGVNPIVQINLRDRNRMGIQSDLLGLAALGIKNITILGGYPAKVGTEPEAK
EVYDLRTMELVRYVKTFIEEGKLFDGTLMEEPPQMTIGTVENIAGKPIPELIDSLESKVE
AGANFVRTQLVFDIDLIEEWMEEARRRGLHERVTIMASILPLRDAAHVDKAIQIPGIVVP
EWVKKRLAMNDSEEEGLQIATDIINKLKKIEGMKGVHIRPIGGNEDSVRKILTKAGLSPF
KKNLAVV
>A0A431LXU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium|TrEMBL
MKVTEHIQQAKSTLLSFEVLPPLKGKTITSLYDHLDPLMEFKPSWINVTYHRSESMFKKK
ADGSFEKVEVRKRPGTVGICAAIMNHYKIDTVPHLICGGFTKRESEDALIDLNFLGIDNV
LVLRGDAAKNETSFEPEPDGHAHAIDLQKQVVNLNHGIYIDEDIRDGGKTNFCIGTAGYP
EKHFEAPNLDTDLQFLKEKVEAGADYIMTQMFFDNQKFFAFVKACRAMGIQVPIIPGLKP
ITSKKQLTVLPRIFHVDIPTDLSNTILNCKTDAEVETIGTTWLIQQSKELKAAGVPVLHY
YTLGKPKVIRNVVKEVF
>A0A2E0Q6Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacteraceae bacterium|TrEMBL
MTGRTNHSHDGNRDASRSASEPLFGGLPGDIDVSFEFFPPKSEKMEAQLWDAVTELKPLG
PQFVSVTYGAGGSTRERTHKTVARIIAEAGIPAAAHLTCVDASRKETQRIAEHXWEAGVR
HIVALRGXMPRXDGTLGPFEPHPDGYANAEELVRGLKEVADFEISVSAYPECHPDAQSPQ
AEIDYLKRKIDAGADRAITQFFFSPETFFAFLEKTDKAGIDVPIVPGILPITNVAKAREF
AGQCGAEIPQWMDNLFEGLDRRPAARQLVSATIAAEMCRRLYAGGIRHYHFYTLNRADLA
YAICHLLGMRPRENAA
>A0A4Q3AY48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium|TrEMBL
GKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKEQENGLLQKVSY
RKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDNVLALRGDARSA
DTAFIPTKGGHCYATDLIEHIKNHNDGKFLHEDIETFKSDFCIGVAGYPEKHFEAPNLNA
DFKYLKKKVEMGAEFIVTQMFFDNQKYFDFVKKCRDNDINVPIIPGLKPISTLTQLNVLP
KIFHIDLPEELTDALSHAKNNAEAKEIGTEAMIKQCKELMDFGVPVLHFYTMGKPEQTKK
IAKAIF
>A0A316J8A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falsochrobactrum shanghaiense|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLKPAFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATRDEVDHVAREFAALGVERFVALRGDPASGIGA
QYVPTPGGYQNGAELVSGLRNISDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGILPIHNFRQVSNFCARSGTHIPSWLEERFD
GLDNDAQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMLGIRPKTETAV
QAA
>A0A2U9BY12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scophthalmus maximus|TrEMBL
MVNQAPRGEGSWSDSSGASNSGGESSKESSRSSTPVLDADRSDRLRDKMRRRMESADRWF
SLEFFPPRTTSGAVNLLSRHVARRITEDRTRVTTGDPGSDKETSSMMIASTAVNYCGLES
VLHLTCCNQTREIITGHLAKAKHLGLKNIMALRGDPVGADWEEEDGGFNYAIDLVKHIRS
EFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVITQLFFRSDTFLKFLDDCR
AIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITNVIEPIKDNDAAIRNYGIHQAVE
MCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRP
IFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLHMWGEE
LMKEESVFEVFTCYITAQPNCSGQKVMCLPWNDEPLAPETNLMKDELEKVNRRGVLTINS
QPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVH
GRNLTNALDFQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYEDESP
SRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIEDMFEMLDAPPEPV
>A0A2E5DJ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacteraceae bacterium|TrEMBL
MEAPLFSGLPGDIEVSFEFFPPKSDKMGETLWQSVETLAPLGPRFASVTYGAGGSTRXRT
HQQVVRIQNEAGIPAAAHLTCVEATREQVDDVARHYWEEGIRHIVALRGDPPDGQSRYSA
HPGGYANAAELIAGLKKVADFEISVAAYPEVHPDSSDRXADLDNLKAKFDAGATRAITQF
FFEPECFFDFRDQAAAAGIKGEIVPGIMPVMSFAAVQRMSGLCGTAIPHWMEGLFEGLDE
RPEARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKA
>A0A354QRS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp|TrEMBL
MSSPSPSLSFEVFPPNPAVGNEKIMAALKEMQDLVPHFISVTASNNKFNIEETTVRLADF
ICNDLHIPTIAHLPAVYLTKEMVTETLTALDKVGVHKVLALRGDILPDVEPQKDFVYATD
LIEYIKKEAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDTGCSSLLTQLFFDNESFYD
FQDKCILAGIEVPIHAGIMPILNRNQVLRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSDTAHRIYQVTHTFFDK
>F8ADS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfatator indicus (strain DSM 15286 / JCM 11887 / CIR29812)|TrEMBL
MSEEKKYFSHLERVLKEGHFAVTCEIGPPKSADPEVVREKARIIRGYVDAANITDCQTAI
VRMSSIASGVLVREEGVEPVIQMTCRDRNRIAIQADLLGAAALGMRNLLCLTGDHPKFGN
HPEAKGVFDLDSIQLLDMVRRMRDEKKFQCGEEIRGKAPEFFLGAAENPFADPFEFRVHR
MAKKAAAGAQFIQTQIIYNLERFRKFMEMARDLGLTEKLFILAGVTPPKSFGMAKYMKYF
VPGLDVPDEILSRLKDAKDKKEEGIKIVVEIIEQVREIPGVAGVHIMAIEWEEAVPEIVK
RAGLEARPFAEEVKPLVKEERVPEVALPEEKPEEKAPEEIVPPKVDVPVEALKSVFSSLR
SSMDALREGINMLHEGLASLEKTLLGGEVPPIEERPSIEEVSPKPEVPSITREEEEKAKQ
IADLLSAAKAAQEAVDYDKALSLYEQVLKLEPENEPAKNAIEVIKKEQKIAELLNKAKEK
LEAKELDEAEKLFKEVLDVIPEQEEAKAGLVKIEELRAKEKPPVEEKPPAEEAPPVEEKP
MEKPEEKPTVTAEAPEVSEILVFSDLSSEYRDVSERAAGIPEDVYKEPGTAWIKEVTIGE
GDKKIAFGGTNVLPFHLFEGEMKNPPRVAMEVLDVKPEDWPESIAKYFEDVFADPGDWAK
KCVEVYGAEAINVYLVGTDPNFMNLEPAHAAKVVEKVANAVDVPLVIWGSGSPEKDVEVI
REVANVLGAKNVMVGPVVDTNHQALGATAMGYGYALIASSPIDVNLAKQLNILLENIGVP
LDRIGMDPSVGAVGYGLEYTYSVMERIRLAALYAGDDKLQVPFVINVGREVWKTKEAGLP
SDEMLGEQEIRGIALEAITAISLLMAGGDFLIMRHPKAIEVTQKIIKGLMAV
>A0A1M5T5Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio fibrisolvens DSM 3071|TrEMBL
MKIENYLKNKTLLADGAFGTYFAQKYGSGALPENANITDPNKVIDIHSDYIKAGANLIRT
NTFACNTLNLGEDMNKLSECIIAGCRLAFMASSLFSNVSDSNAVSSNPDGEEKRQIFVAG
DIGPIPFVPGQDDEKISDEYLFMVKTMYDSGIKIFLFETFAGIDNIQKSLNWLKAKKEDE
PDLFVWVQLCSNQHGYTNEGIHVRNIIKELSSKKLVDAAGLNCGIGPASMRNILDEIDFT
GIRYVSAFPNASFPQGMLSRPIFSGNEKYFASKMEEILTLGADIVGGCCGTNPKYTEEVA
RIDLATKKPHAFKGEADAEIKVREKNSAFWEGSTDKKLIAIELAPPFGADDKKLMDSANA
LTKYNVDAITLPDSPSGRTRADSILAGLKVSTETGISAIPHICCRDRNVISLRSGLLGAY
MNGIRNILAITGDPVPTLMRQEARSVFNFDSVGLMKVIAELNREEFYKDPITYGGALSYN
RPNTEVELSRMIKKIEAGASFFLTQPVFSDSDIEKLAFFKEKMKEVDPDVKLFCGLMPLV
SYKNAQFIQNEMSGINVPEEVIQRYKPDMSREEGEMVGVSVVRDVIAKTSDFSDGYYFSI
PFNRVYLLDKIL
>A0A6N9QE87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKIPEIFERKKPVFSLEIFPPKRQSGLDKIYDTIEKLAVCQPDFISVTYGAGGNMADNST
CDIASNIKTKFGIEPLAHLTCVNSTMEDVTEMIRRFSEAKIENVLALRGDIVPGEMIQKE
FFHANELAIEVQRNSGLQILGACYPEGHSESKNLREDISNLKYKIGAGVKVLITQLFFDN
QLFYDFMVQVRNAGIKAPVSAGIMPIVSKKQIEKTVALSGASLPHEFTKMISLYENAPEE
LYQNGIQYAVDQIRDLLEHGVDGIHLYTMNNPDVSLAVYEKIKDLL
>A0A1J5EMG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium CG2_30_60_27|TrEMBL
MKSGSRLERILARGEFAVTGELGPPKSGDPEVVREKARLLKGSVDAVNITDCQTAIVRMS
SIGAGLIALQEGVEPVIQMTCRDRNRIGMQSDILGAAALGLKNLLCLTGDHQKFGNHPMA
KGVFDMDSIQMLGMVKAMRDDQVFQCGEAIKDHAPKLFLGAAANPFAHPFEFRAARLGKK
VAAGADFIQTQIIYNVEKFARFMEMVRELGLLDKVHILAGVTPPKSLGMARYMKKFVPGM
EVTDEVIKRMQGAKDKEDEGINICVDIINQVRAIQGVAGVHIMAIEWEKAVPEIVSRAKL
GPRPVFADDGTAPPLAAARQPGATAAVPMVLRGPIAGEQPGIPEGDDAGEHAMNERERQI
ALEQVRGGLEALKEALGISDKQFEALTKFTAACATLEKEPPAGVAAVTAAAPPPVKVEAK
VVEKAVEPKAAEVAAKKAAAEAASKAEAEKKAAEEAARQKAATEVASKKAEAEKKATAVA
ASKAVPAPKEAPPAKPPAQPAVKPSPRSSAAETPAALAVETTPLAERAARVPDNSYKQVY
SGAIRETVLGSKGHTLTVGGAKTLPFYLFEGEMPNRPIVAMDVLDVAPDEWPASLARHFE
GVLNDPVAWARKCVTDFNMEAICLSLVSTDPNGLNRPSSEAAKKAVEVVNGVDVPVILWG
CGNADKDTETLREITAMIGDKKVCLGPLSDANYRSLGATAMAFGHPMIAASPIDVNLAKQ
LNILLENLGVSLDTVLVDPSIGALGYGIEYSYSVMERIRLAALTQKDEKLQVPLICNLGR
EVWKAKETRLPTDAMIGDQERRGVLMEAITATCMLMAGGEVLIMRHPRAVALTKALISGL
MG
>I0BPN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus mucilaginosus K02|TrEMBL
MKPGLREALRSQVLVGDGAMGTYLYQMGFPIGISYEELNLLKPDVIMDVHRRYYEAGARL
IETNTFSANREKLSKFGLEGEVEAINRAGVELARRAVGEDAYVVGAVGSIRAGKRKNVRT
NKVREDLREQISILCDTKVDGLLLESFLDLDEMLIALKEVRRISDLPVICQFATEGAGVT
QDGVPLKEAFAKLLEAGADVVGLNCRSGPNGLLRSLEGAAAAEADHPPYSVFPNAGLADY
VDGRYSFPATPQYFGETARRFADLGTRIIGGCCGTTPEHIAAVAGALAGYVPNPEAAKRA
AAAPAAEVAERAAAGAGAEVPTEPSIVDLVRQRHTVIVELDPPKDLDIGKFMEGTEALKK
AGVDALTMADNSLAVTRMSNLALGSIVKERTGIRPLIHIACRDRNLIGTQSHMMGLHALG
IDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKKQANFVIGAA
FNPNVKYLDKAVQRLERKVEAGADYIMTQPVYNAELIEQVYEATKHLSVPIFIGIMPLAS
GNNAEYLHNEVPGIQLSDDVRKRMSGLRGEEGRAMGVQIGRELLDAAMRRFNGIYLMTPF
LAYEMTVQLTEYVWEKAGRRHLSPLPK
>A0A7Z0ET20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis aegyptia|TrEMBL
MLAAPTRPVALRNPTPRPRHIRELLHAGEPLFSFEFFPPRSQQAQERLWRAIREIEALGP
SFVSVTYGAGGSTRGMTVETTERIATDTTLLPVAHMTLVDHSVAELRHLIGRFADAGVSN
MLAVRGDPPGDPDGEWVRHPQGLTYTEELVRLLKDSGDFCVGVAAFPYKHPRSADVETDT
DHFVRKCDAGADYAITQMFFDPEDYLRLRDRVAARGCEIPIIPEVFPVVRTSFIPRSEQL
SGAKFPADLAAKFESFGDDAEAVRAFGIEYAQRMCQRLLAEGAPGIHFITSNRSTATRQI
YQEVSGRRGERSAGAARP
>A0A356P821|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp|TrEMBL
MKNVIELKRKLDNGDFIFTTELGAINGTLIEDSLTKAKDYIGLDAINVHDCPNANLRMNS
VMAASILKRELGIETIPHFTCRDRSLLGTQADLLGAHALGIRSILATTGDAPQHGPYHGS
KAVYNYNSYELIKLIDTMNSGKDANEVDIKGSTNFVIAATATPGATNMTVEIERMKKKIE
MGADFFQTQPVYDLVKAREFLKEAKVLDKPILLGIMPLISLNLVKFINNKMPGVTVTDDI
INQMEDGKKGLEIACELISELFEDISGIHIYGMGDVQTTNKIIEFTKSLNLKRRHVI
>A0A1P8XF32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. MS1601|TrEMBL
MNVRNVERRTLSVVDRIAEVGRDRVPFSVEFYPPRDAAAEARLWRAARTFEPMGPAFVSV
TYGAGGSTRDRTVRVVGQLADATTLLPVAHLTAVGHSVGELRAMVGAYADRGIHNVLVLR
GDPQGGVHDEWVKHPDGLEYAVEMVDLVRRLGDFHVGVASFPEGHPRAGGLEQDTANLVG
KLRAGAEYSITQMFFDVQDYLRLRDRVVAADPEQGAKPLIPGIMPITSLRVLRRQCELAG
SQIPATLLDRLTAAAGSGAEENRDEVRKVGIELATEMSARLIAEGAPCLHFCTLNFARAT
GEVLANLGMMARA
>A0A5Q2FEH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raineyella fluvialis|TrEMBL
MEPRTIDELLRAGERALHSFEFFPPKTLEGDAMLWQSLRELDDLEPDFVSVTYGASGSRR
DMTVTITARLAQLMKERLARDPQAHVMQVMGHLTCVSQPVDELAEVVDKYAEAGINHILA
IRGDMPGGPLEPWVRHPQGLDNATELVRLVRRRNPAAVIGVAAFPDLHPDRRDAALDAHI
LVEKQEAGASFAITQLFFEPDRYFELVERVRALGSDLPIIPGIQPVTNVSQIERFADLSG
APLPDRVVARLHAVADDPDEVRRVGVDIGVELCERLLAGGAPGLHYFTLNRSRATREIFS
RLKQTIPGA
>A0A845MH82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sneathiella chungangensis|TrEMBL
MSGIPQSNEISSGLLVGSARNRVEVSFEFFPPTSDALADKHWQALMRLAPLGPKFVSVTY
GAGGSTRERTHALVSRIRQETTLEPAAHLTCVGASKGEIEEIAERYWQSGIRHLVALRGD
PPEGFDAFKPHPGGFAGSVELIDFLKKKHDFEISVGCYPEIHPEAKSSLADIDYLKRKMD
AGATRAITQFFFDPEVYLRFVDRARAHGITIPIVPGILPVTSYSKIHQFSRQCGAQVPAW
LTHLFEDLDEDPATRNLVAAMVASEQCLQLQRAGVTDFHFYTLNRADLVYSVCHTLGLRP
EKNQITC
>A0A7C6YFX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MEIKKLFQENHVVYSYEIFPPKVDSPLERVYDTIGELAGMQPDYISVTYGAGGSAQNNRT
TRLTGRIRKRYGVESLAHLTCIGATKQHIDRTLDELQAHSVRNVLALRGDIPGSGFDPQD
FSNSQELIRYVKGRGFGVAAAAYPEGHAETKVKDKDIEILKWKEEAGADYFITQLFFDNE
RFYEFMDKVMKKGIGAPVQAGVMPITKARQIKRVVELSGASLPESFLRMIDRYGHDEAAL
RDAGIAYATEQISSLIAAGARGIHLYTMNDASVAGAVTRNIDSLIRAVNGKEAM
>A0A4P5ZGX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktothrix agardhii CCAP 1459/11A|TrEMBL
MNRFRTACQTLDEFIVTAEVAPPKGADPSHMIEMVRLLKGRVHAVNITDGSRAVLGMSSL
AASIILIHHGVEPIYQVACRDRNRIGLQADLLGAQALGIRNVLALTGDPVKAGDHPDAKA
VFDLESVRLLQAIDKLNQGKDWNNKTLPDGATDLFPGAAVDPQSSSWSGLKSRFERKIEA
GAQFFQSQLITDFDRLDKFMTEIADSSKKPILAGIFLLKSAKNARFINKYVPGVCIPDSI
IDRLEQAKHPLEEGILIASEQVKIARELCHGVHIMAVKREDLIPKILDLAGIKPLF
>A0A3L7A5N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycetocola tolaasinivorans|TrEMBL
MFPKEIGVATTFSFELYPPRSAAAADALEVSLAHLVASSPEFISVTYGAGGTTTDRSLRV
LQQLRAGGVDAMAHLTCVGSSYAEASAMIHEFLDAGITKFLALRGDPPVGAKEGENFLGD
LGSAGELVQLIHRIRAEKAQFVQPPLAGFPRGTQVRPQPKVTIAVAAFPNGHPRSRSVSQ
DLDTLLAKEAAGANLAITQLFFDPEDYLRFVDQARAAGITMRILPGIMPVLSPERLHRIV
QLTDEKLPLELLRKLEAQGSPEAQFEVGVDHAVSLSHSLLNGGASGLHLYTFNQHPAVLR
VLRETGLYVPEKEYA
>U5CT83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldanaerobacter subterraneus subsp. yonseiensis KB-1|TrEMBL
MLKNEKLCNKLKEKKFVITVEISPPKGIDVTKTIEEARKLKGVADALNITDSPMANMRMS
PIALAHILQDHLNIETIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDNPSLGDTPQ
ARGVYDVDSVGLLKIIKALNSGFDYNGNKLDYPTSFCAGTTANPNDLRDEAIEKLHVKVE
AGAEFIQTQPVYDEEILFKFLDKVKDLKVPVLVGILPLKSYKMALRLMEKVPGIEIPEKV
LKRLQQGGKEEGINLSAEFIKNIKSEVAGIHIMPMGSVDFVFDIISKVEGIAISAKKAET
K
>A0A061ELE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Theobroma cacao|TrEMBL
MKVIEKIRTLQEEQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGSDGVATPEAYQNDLEYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPADITNALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRFLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSQN
PSYGALTDYQFMRPRARGKKLHEEWATPLKSIDDIQEKFKSYCLGKLKSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKL
DALIAKCKALSFITYLAVNKNGDLISNIGVADVNAVTWGAFPAKETIQPTVVDPASFMVW
KDEAFEIWSRTWASWYSDTDPEGVQSKKLLEEVQSKYYLVSLVDNDYISGNIFAVFEDI
>A0A3D0HGX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobium sp|TrEMBL
MSILSRLKKPSVKVTPAVKELVSNMRYELIPMKSIEQGILDLPTGAPVSVTCSPAKGISA
TQEISARLIAAGHEVVPHFAARLVESREHVTKLASWVREQGIKEVFLIAGDAENPAGPYQ
DGVELLRDFLDSNSGVERVGFGSYPDGHAFISREDLSTALHHKQKLLEEAGVQGLASTQM
CFDVPLIRSWLEQERNNGFKIPIQLGVPGVVDRTRLMTLGVRVGVGQSMRYLSKNKTSII
KMLSPGGYDPTELVAGLAKDAKRLNIVGLHSFTFNSVADTAVWQREVMAG
>A0A350J6U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKITDILNQDKMQLSFEVFPPKQETSFESVLEAAGKIAELRPSFMSVTYGAGGGTSAYTL
RLGSEIEKKYDVPMLAHLTCISSDKATVRDRILEIKEAGIENIMALRGDIPADRIDEDRS
SWDFHYAVELIREIKEIYPECCIGAACYPEIHPESANQREDIKHLKEKVDAGADFITTQM
IFDNNLFFNFLYKLRDAGVTVPVLPGIMPITRANQVERAIKLSGAYMPVRFRSIVDRFGN
DDEAMKRAGIIYAADQIIDLYANGITNVHVYSMNKPDVAKGIKDSLESILGRNFG
>A0A150N351|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus stearothermophilus|TrEMBL
MGLLDELKQRILIADGAMGTLLYSHGVDRCFEELNLSNPDEIIHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGGAYVLGTIGGLRTLNKSVVPLDEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALSRLEALGADVVGLNCRLGPHYMIQSLEEVPLPNRAFLSAYPNASLPDYRDGRLV
YETNAEYFEEAAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTRRSVIVELDPPKQLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKEQLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPVYSEEKIVQIYETTKHLATPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACSGDPVEAAREGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A521WJB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MRRPVQVSFEFFPPADEAMERTLWASLQRLAPLSPRFVSVTYGADGSTRDRTHRLVTRVL
GETGLTGAPHLTCIGASRGEIQDIARRYWDLGVRHIVALRGDPPAGAGAYVPRPDGYAWA
ADLVAGLRSVADFEISVAAYPETHPEAASAEADLDNLKRKLDAGADRAITQFFFEPERFL
RFRDRCAARGISAPLVPGILPITRFPQLLRFAARCGASVPGWLIERFEGLEDDPETRMMI
AASVAIEQAARLRHEGVDEFHFYTLNRAELTYAICHALGVRAR
>A0A7U8J6K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella abortus bv. 2 str. 86/8/59|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A6L8IEF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MQFEDEPLVPGERLPIRPGHSSFGRLERVLRAGGFAVTAEIAPPDSANPAEVYERAALYD
GYVDAMNATDGSGANCHMSSVGMCSLLCRRGYAMVMQVSARDRNRIAIQGDVLGASAMGV
ASILCLTGDGVDVGDHPQAKPVFDLDCMSMLSMIRHMRDESRFLSGRKLTEPPPVFLGAA
ANPFAPPLDYRPLRLAKKVEAGAQFVQTQYCFDIDAFKRYMAAVRDAGIHEKVFILAGVG
PLASARSAEWIRANVPGVHIPDAVVRRLKGAVDQQREGVNLCIETIRRIREIEGVHGIHI
MAYRQEHWIAEIVERSGVLEGRRPWQPPLDWQNAAWDQVHPAMPNAQGRQAMEEIS
>A0A3L7DDU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus stearothermophilus|TrEMBL
MGLLDELKQRILIADGAMGTLLYSHGVDRCFEELNLSNPDEIIHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLMAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALIRLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTYRSVIVELDPPKQLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKEQLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVYEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACGSDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A890D168|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida auris|TrEMBL
MKISKKLEHAHSCSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYELNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALKKAHASGCQNILALRGDPPLD
GSESTGDFKYAKDLIRYIRKNYGDHFNIGIAAYPEGHPEEEDETKLLSYLKEKVDAGADF
IITQMFYDVDNFISWCSKIRKIGVEIPIIPGIMPISTYSAFIRRAKWSQIRIPQHFLDAL
EPIKEDDYAVREKGTALVGEMCQKLIDSGYVNHLHFYTMNLERSTIMVLEHLNLIEHVKD
NAVVGDELPWRKSLHPMRSKESIRPIFWQNRKYSYISRTSGWDEFPNGRWGDSRSPAFGD
IDLSATELLRQSPKRAYELWGCPQSLQELSQIMISYLKGEIKSLPWSDGPIGDDTEVLKP
ALIEMNTNGIFTLNSQPALSAVKSNHEVFGWGPKNGFVYQKQYLEFFIHKDLVHTLLNRV
EAHNAKDAHSVITYYAVDKSGSLLTNAHDDDINAVTWGVFPGEEILQPTIVEKISFLAWK
DEVYRLLDEWVKIFHTKTITELVEEDKVNAFSKLLTSFGDNFVLCNFVNNDFTSGNNVIF
DLFDGLQVSSL
>A0A7Y8CUS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. P7759|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQAHSFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITNMCEDLLNGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>D4JR65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] siraeum 70/3|TrEMBL
MKIKDLYTPGRTVFSLEVFPPNKNFPIETVYDAIEGLAAINPAYISVTYGAGGNRANRST
CEIASHIKEKYGIESMAHLTCINSTRDDVDFMLDDFAANGIENILALRGDNKPDEEPKND
FPHASDLTAYIASKGSFDIAGACYPETHVDAESAEEDIKNLKIKVDAGASHLVSQLFFDN
SCYYDFEKRARAAGVDVPIAAGIMPVTNKKQIERMVTLCGASLPSKFVKMMQKYENDPEA
LRSAGIAYAIDQIVDLISNDVQGIHLYAMNNPAVASRIYNGIKDLL
>A0A534BW80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNRIPLADVVKWLQAAGEPSRLRLLALCTEGALSVSDLAQALRQSEPRVSRHLKILSEGG
LIVRMRQGQWVHYRVADQAEAASFVRGLLAQLDRSDPVLLRDRTGARAAAAPRIERAAHG
AESRLGRAIAGFITASGLSEPRGAVLVIGVSHPELLECAARASPRCTAVAPSRRAAQAAR
AFAERRGLSCRILKGAGVELLGDADMVRLGEAFAAVLVDSSAGEEAFARTLQRARGLLAP
GGRLCHRRGGGGGRGRACGMSDESCAMNAESGRTPIRVSFEFFPPADEAMGAMLWKSIER
LAPLAPRFVSVTYGADGSTRERTHNVVTRIQRETPLTGAPHLTCIGASREEILEIARGYW
DEGIRHMVALRGDPPRGEGARRPNPRGFRYASELVAALAGLAPFDISVAAYPEVHPEAGS
AAADLENLKRKIDAGATRAITQFFFDTDAFLRFRDALAAAGVHAPIVPGILPITRFPQVL
RFAKACGTSIPGRLHERFAGLDDDHETRRMIAASVAIEQVEALRRHGVSEFHFYTLNRAE
LTYAICHALGLRPHARSASAALQEARA
>A0A0L0NNM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida auris|TrEMBL
MKISKKLEHAHSCSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYELNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALKKAHASGCQNILALRGDPPLD
GSESTGDFKYAKDLIRYIRKNYGDHFNIGIAAYPEGHPEEEDETKLLSYLKEKVDAGADF
IITQMFYDVDNFILWCLKIRKIGVEIPIIPGIMPISTYSAFIRRAKWSQIKIPQHFLDAL
DPIKEDDYAVREKGTALVGEMCQKLIDSGYVNHLHFYTMNLERSTIMVLEHLNLIEHVKD
NAVVGDELPWRKSLHPMRSKESIRPIFWQNRKYSYISRTSGWDEFPNGRWGDSRSPAFGD
IDLSATELLRQSPKRAYELWGCPQSLQELSQIMISYLKGEIKSLPWSDGPIGDDTEVLKP
ALIEMNTNGIFTLNSQPALSAVKSNHEVFGWGPKNGFVYQKQYLEFFIHKDLVHTLLNRV
EAHNAKDAHSVITYYAVDKLGSLLTNAHDDDINAVTWGVFPGEEILQPTIVEKISFLAWK
DEVYRLLDEWVKIFHTKTITELVEEDKINAFSKLLTSFGDNFVLCNFVNNDFTSGNNIIF
DLFDGLQVSSL
>A0A7W8E3E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulicella aggregans|TrEMBL
MERTKELSRLLAFVGSGHGHPGQDINGTAEDQQPGPVLCDGAMGTMFYGGGVFINRCYDE
LNVSQPDLVRGIHAEYLQAGARIIETNTFGANVVRLERYGLGDKVREINLAGVRLARESV
NQIREKQASEALVAGALGPLGVRLAPEGKLTAEEAFEAFREQVAALTEEVPGVGPDLLIV
ETMVSLAETEQAVKAARAVAPNLPLVVMVTVDEAGNCLDGTTAEDAATKLTEWGVDGLGC
NCSSGPAVVLNAVERMRAVTTLPLAAMPNAGMPRSVEGRNIYLTSPEYLASFARKFVKAG
VTFIGGCCGTTPAHIRAMRAALRALEAQTSAVQVVAETSSAEVLENKVQPPALGERSKIG
SMIAAGDFVTLVEIVPPKGIDCSKELEGAALLHRLGVDAINVPDSPRASARMSAQSLCTQ
IQQHVGIETVLHYTCRDRNILSIQSDLIGASSIGLKNILCLTGDPPKLGNYPDATAVFDV
DAIGLVKIVKKLNHGLDIGQNPIGGSTGFTISVAANPGVADIDNEVRRFAFKVQAGAEFA
ITQPVFDLRLLAEFLKKIEGFRIPVIAGIWPLTSLKNAEFMKNDLKVSMPAEIMARMAAM
TSPEAARAEGIAIAREMLAEVRGQVQGVQVSAPFGKYTAAAQVLGFSDGETA
>A0A496WH20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNTAATTRFSYEFFPPRNDNMVRKLWRSVGQLERLDPLFFSMTYGALGSAQKVSIDSAIE
MHQESPVAVAAHLTCANASAFEIEQIAKQYYDSGIRRFVALRGDAADSTDGESVYGYNSA
VELVEALRKLGEVDISVAAYPEVHPQAQNAQSDLAHLKRKLDAGANRAITQYFFDADCFL
RFRDQARRIGIEKPIIPGILPVHDYQKVKAFSQRCGATVPTRFEVKFASVANNPAAQYRL
SLDLAVELCERLVREGVDHFHLYTLNQTDMCLDISLALGASVVTPQLFSAA
>A0A6B1ASM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAPQFSVEFFPPRTEAGRGKLDLVHEELTALGVNSFSVTYGAGGSTKEGTRSIVLDYNAA
GSAVAPHLSSTGQDLDFVGDLLNDYRDAGIRRLVALRGDTPPGQKRASKGFYARDLVEFV
RRHTGDHFHIKVACYPDLHPETPSFALEIKYFRQKIEAGANSAITQYFYNADSYFRFVDS
CREAGIDVPIVPGIMPITNFDKLSAFSDKCGAKIPDWLAGRLAGFGDDEAGLRRYGDEVV
SELCGRLLEGGAPGLHFYSLNQAGPVRRIWENLGLSGSR
>A0A432G8X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
METQYSFELFPPKTEKGMEKLKGVVTELNALEPAYFSVTYGAGGSTRERTFATVDWLRGQ
GIDTAPHLSCIGAGREEILDILNRYRNEGIRRIVALRGDLPSGAGLGGLGEFNYANELVA
FINANFPGEFHIEVAAYPEFHPQAESAWKDLDNFQRKVEAGAHGAITQYFYNADAYWRFV
EDCEHRGIEIPIVPGIMPITNYVNLARFSDACGAEIPRWLCKRLEAYGEDLESIFDFGVD
VVSDLCARLLDNGAPGLHFYTMNQSAAVKAIWSRLGLDFVVKLLFLQLLKLSLFHYLKEA
S
>A0A3D0ZXK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTERFFSLEYSAPRTNEALERLKKTHNRLNKLKPHFCSVTYGAGGSTKEGTQQAILALSS
GSAPMAPHLSSGSEPLSAIDELLKTYRSAGVSRLVALRGDQPSGILGSNTMTHANELVRY
VRETTGDHFHIDVAAYPEIHPESETVESEIYYFKAKVEAGADSAITQYFYNPDSYFRFRD
LCQKAGVNVPIVPGIMPITNYEGLIRFSSLCGAEIPRWLDKNLKSLKHDKDSLKAFATDV
VSDMCRRLLDNDAPGLHFYTLNQAMPTLRIWNNLELS
>A0A3D1A3B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
PKTYLDFLVDTEALGIDTPIVPGIILLTDFPRISSFAEKCGATIPDWITGRFANIEPNSK
DAVSLAKEITIRQCSELVENGVRMFHLYTMNRLDSIASICETLQNEFAPKGCMGS
>A0A4R3EBR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. BK604|TrEMBL
MNAFRPSRHGSRRPRVSFEFFPPKTPEMEVALWESVRRLEPLKPSFVSVTYGAGGSTRER
THNTVKRMVDETGLKPAAHLTCVSATCGEVDEVIRSYWTAGVRHIVALRGDPAGGLGTAY
EPHPQGYHQTCDLVAGIRKIGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRARGIDIPILPGIVPVQNFKQTANFATKTGASVPQWLADRFEGL
EDDAATRRLVAAAVCAEQVLDLIDRGVSDLHFYTMNKADLVYAICHLVGLKPDKSVQQQA
AAE
>A0A534BEM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPIRPGHTSPGRFERVLRAGQFAVTTELDPPDSADPEEVYRRARVFDG
YVDAINATDGSGANCHMSSLAVCALLTRVGYAPVMQISCRDKNRIAIQGD
>A0A0D8HQ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. (strain AD45)|TrEMBL
MTFDAVRGRSSDGWASRTPSIVDRITSSTGSRIPFSVEFSPPRDAEAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSIDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPDGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
HDTKYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAFDPEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGSQENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTSDVSTDSQASV
>A0A1A8IDF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius kuhntae|TrEMBL
MVNQVQRVDGSWLSCKSDSSGTSNSGGESSKESSRCSTPVLDAVRSDRLRDKMRRRMESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEEEEGGFNYAV
DLVKHIRSEFDDYFDVCVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTF
LTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKREESVFEVFTCYITGQLNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDAVVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRV
NYHIVNVHGRNLTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLKSCLWQVLDDMFELLDAPLETLADGMPG
DGSHGDGSHDNGTLAE
>A0A1N6QJD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. RU20A|TrEMBL
MSMIDENPLGPHLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTSPPQVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFKEYMKKVRDLGLHEKCYILVGV
GPMASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKDIEGVAGIH
VMAYRQEEYVSEIVHESGVLKGRTPWKRRPASEVRELVDQMQEDAARLS
>A0A368BWK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGSQEDIQLSASNLRMLNDLQNAYMEVIPVPKIEQKLETISRDTHLAITCSPNKGVDETI
ELSEILVDMGFNVTPHVAAKCVTNESHLVSIVEKLQEKGIESIFVPGGDKPEPAGDFKNA
YELLNCLNSIDHKIKNIGIAAHPEGHPDIEDEVLIEELQKKKNLATYIVTQMCFDAELLG
DWLCDIKDRGIDLPVWVGLPGVIERGKLLRTSLRIGVGDSLRFLRKKTQVASELMKSSTY
YPDNLVTDISEYEKINQTNLAGYHIYCFNQIEISEKWRNEKITSLR
>A0A368BXE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MITESLEASKNNFIFTAETTPSVSTNLNENVEKISNLIGVADAVNITDAPNCKTKLSSLV
VAGEINKSGLDVILQITGRDRNQIALESEILGALSLDINKILCLSGDRPPEDGPMAVNEM
NSSDLINLLKLMSKGNLSDGTEIKEPIELISGCADSIHDHFVRDKHSDFFVEKVNMGVSF
VQTQYCYDIDLCKKYSQFIQENNLSASTKFIIGLGPLKSAKQASWMRENLYGVKIPDSII
NRLDQSTSPLDEGKKICEEIIKELMDLDGISGVHLMGPNCEDQCADLIKIFR
>A0A352KPB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
RLAAYGDDKESLQAFGIEVVSDLCNQLLSAGCPGLHFYSMNQALIVEQVCNNLHLPHKST
>A0A2D7FYQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSEACKTPISFEFSAPKTEAAFSSLRRAYSRLSRFQHEFISVTYGAGGSTRDGTKHAVTA
LSSEGFTVAPHLSFGGDDEATIAGLLEDYQAAGIKQLVALRGDRQSGQGSAKMVHAAELV
EFIRARTDDWFTIHVAAYPEIHPESISVATEIEFFKQKVDAGADCAITQYFFNVDAYQQF
LAECHKAGITTPIVPGIMPITNLAGLQRFSSICGADLPRWLTKRLETLDGDDVAVKDFGC
EVVTRLCERLIEAGAPGLHFYTLNQSKPSARILENLGY
>A0A3B8RAV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTTLPISFEFSAPKTEAAASGLRRAHDRLKRFDHEFVSVTYGAGGSTRDGTKDTVIALSQ
DGASAAPHLSFGGDNSETIGELLKAYQDAGIRRIVALRGDRQSGLGTPKIVHASELVKFI
RETTGDWFHIEVAAYPEIHPESKSVRTEIAFFKEKVDAGANGAITQYFYSAEAYFRFVEE
SAKAQIRIPIVPGIMPITNLTGLQRFSQICGADLPRWLVKRLEDFDDDDALKDFGAEVVT
RLCEQLIQGGAPALHFYTLNQSKPSARILDNLGF
>A0A1A8IZ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius kuhntae|TrEMBL
YPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTFLTFVDDCRAIGVTCPILPGI
FPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIHQAVEMCRVLLDSGKVP
GLHFYTLNREVAPTEVLRQLGLWIEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIY
RTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEELKREESVFEVFT
CYITGQLNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTDA
VVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAHEMQP
NAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNY
FLVNLVDNDFPLKSCLWQVLDDMFELLDAPLETLADGMPGDGSHGDGSHDNGTLAE
>A0A0H5RI09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spongospora subterranea|TrEMBL
MKIIDKINSTKGPFYSFEYFPPKTDEGVENLYRRLERMALLEPSFVDVTWGAGGTTAQLT
LEISANAQKYIGLETMMHLTCTNMPATQIHEALLQAKEAGIKNILALRGDPPIGAESWEK
CESGFGQAADLVEYIRREFGDYFGVCVAGYPEGHSECADVESDMAYLKAKVDAGADFIIT
QLFYDVDMFLEFVAKARDIGITCPIIPGVMPIQNYSAFKRMTTFCKTKVPKDIFDRLEPI
KEDDAKVKDYGVELGVSMCQKMLKAGIPGIHFYTLNLETSVKRIMQGLGFLISEARAEEG
EGYKRLPWQTSEVQRRATEAVRPIFWANRPHSYMQRTLTWDEFPNGRWGDSRSPAFGDLA
DYHIFSAMSVSRIKDRQKLWGEAPQTLKDIYSVFEALVDGQVSYLPWCQGPLQSETKQIW
QLLKSLNRNGFLTINSQPSVNGASSSDKSFGWGASNGYVYQKAYLEFFTSEANLQRIISV
IGNFPMMTFYAINAEGRSYSNVNADSEGQVHVNAVTWGVFPNSEIIQPTVVDSTSFKVWK
DEAFGLWISQWGNIYPKNSPSRNLIQDIHDKFFLVNIVDNDYVNSDLSKFVNTLESTSVM
RSN
>A0A3C1N5B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSRFAQALSMSEFVVTSELIPPKGVDLEPLFEKAEALNQVVTAFNLTESHTAKMSMDPVA
VGHLLLDRGVEPIVQMTSRDKNRIAIQASILGAAALGISNIVIMGGDSPKNGDHPEAKGV
FDLYSSQVLDAASALNGGADYMGNPLKGAPAMNIGAVVNPGASDPSAEIENLHRKIEAGA
GFFQSQAVYDVDALASFLDKADTDAVILAGIIPIKSVRMARFMNDKVPGINIPETLIAE
>A0A534BSF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNAESGRTPIRVSFEFFPPADEAMGAMLWKSIERLAPLAPRFVSVTYGADGSTRERTHNV
VTRIQRETPLTGAPHLTCIGASREEILEIARGYWDEGIRHMVALRGDPPRGEGARRPNPR
GFRYASELVAALAGLAPFDISVAAYPEVHPEAGSAAADLENLKRKIDAGATRAITQFFFD
TDAFLRFRDALAAAGVHAPIVPGILPITRFPQVLRFAKACGTSIPGRLHERFAGLDDDHE
TRRMIAASVAIEQVEALRRHGVSEFHFYTLNRAELTYAICHALGLRPHARSASAAPQEAR
A
>A0A2E4K0B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MELNPTPIFSIEFYPPRTNADESKLNAVHQQLAKLRPDFFSVTYGAGGSTKEGTKQIVLR
YQQFGSNMAPHLSFGGTDQDEIKILLAAYKAAGINRLVALRGDSPSGGSAITHHRYASEL
VEFIRLETGEYFHIDVACYPEPHPDSKNYQSNVRYFKQKIDAGANSAITQYFYNADAYFY
FVEYCYKAGISIPIVPGIMPITNYANLARFSAKCGAEIPYWLQKRLEGFGNDVAGLREFG
IEVVTVMCERLLAGGAPGLHFYSMNLAKSVTEIWTNLALSDRH
>A0A3C1TWZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
GRVVALRGDLPSGLGNKQNIRYAKDLVNLIQKNHPSWLVEVAAYPEVHPDADNQHQDALY
LKEKIDAGASGCITQYFYNTDSYFYFVDLCRSLGITVPIIPGIMPITNQAKLEDFSK
>A0A673IE98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus rhinocerous|TrEMBL
ICGGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHWFSLEF
FPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLES
VLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLVKHIRC
EFDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAETFLRFVKNCR
AIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGIQQAVE
MCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKVEDVRP
IFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEE
LMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGILTINS
QPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVQ
GKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESP
SRMIIQYIHDNYFLVNLVDNDFPLDSCLWQCTREDMPRQY
>A0A839VEB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas cerina|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGKFAITSEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGANCHMSSAGVCSLLTRVGYATILQISCRDRNRIAMQGEILGGAAMGAC
NLLCLTGDGVQAGDHPQAKPVFDLDSISLLQIARNMRDEHRFESGRRIETPPRIFLGAAE
NPFVPPLDWRPHRLAKKVAAGAQFIQTQYCFDIERLRDFMLKVNDLGLLEGPDRVFILPG
IGPLASARSARWIRENVPGVHIPDAVITRLEGAENQKEEGKRLCMDLLHEIREIPGVSGA
HIMAYRQEHSVAEIIETTGVLEGRVPWYPGRDDPKALNPESPDALQL
>A0A673IBF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus rhinocerous|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAETFLRF
VKNCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGI
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFALLDSPRETQEEGSQS
>A0A4W2GG98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos indicus x Bos taurus|TrEMBL
MDCPKPKVFPVGHCCPSLGMRASEAGSGRLSVPPSISRNSAMVNEPRGNGSPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFY
TLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLSG
EPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGWG
PSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNL
VDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>A0A4U0FIJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella pontilimi|TrEMBL
MKPDLRTALKERPLVGDGAMGTYLYQLGFPVGVSYEEFNLLKPNVIADVHSRYVKAGAQV
IETNTFSAQRGKLSKYGLEHKTEEIKAAGVSIARQAAGDNAYVVGAIGANRAGRRRNLRT
SSIKRDFEEQIGALLAANPDGLLLETFFDFEEMSMALALIRKRSDLPVICQFAVENAART
ADGVPLADAFARLKDEGADVIGFNCRSGPNAILRAMETIPADLGAPLSVFPNAGIPDYVD
GEVIYSASPEYFAASAIRFADLGSRLIGGCCGTTPEHIAAIAGALKTYIPGAAASAPAAA
PAARPVLTAEPAEPPVSGGTGEQEPSLVELVRRRHTVIVELDPPRDLDIKRFMQGAQALK
DAGADAVTMADNSLAVTRMSNMALGALVKETVGIRPLIHIACRDRNLIGTQSHMMGLDAL
GIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGVAFSGKPLKQKAKFIVGA
AFNPNVKYLEKAIERLERKIASGADYIMTQPVYDPALIERIAESTRHLSVPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRRRMSGLEGPAGRAEGVAIARELLDAAMEHFNGIYLITP
FLSYEMSVALTEYVIRNGARAARTK
>A0A1Q6YYC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium 13_2_20CM_2_64_8|TrEMBL
MPHAFDRRLAAGPLLCDGAMGTLLYARGVSIDACFDVLNVSQAKVVQSVHSEYIAAGADC
IETNTFGANRFKLAVHGLASDVHQINLRGVKLARDVRESMGRDVLVLGSVGPLGKYLAPL
GTVTADEARAAFREQAEALLEGGIDAFVVETFSDLTEIALAIETIRTLTDLPIVAQMAFT
DEGVTFAGRSPAEVARTLRELGVRALGANCSVGSSTLYEVLEAMGPEARDVPLAIQPNAG
LPHRIGERLMYLSSPGYMADYAGRMIDAGARIVGGCCGTTPQHIAAMRRVLDARAPASKA
EPRPTSAARVIEALETPGLRTTLAPTLLGRKLEQRSFVVSVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLPTAILVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALGIRNILAMTGDPPRTGDYVNATAVFDVDGIGLLEVLRRMNEGMDATGNGIGEPTSFCV
GAALDPGAPDPGREVERFHRKLEAGARWFQTQPVYDLEVLDRFLARVVGSPVPVLVGVLP
LHSFRHAEFLHNEVPGITIPDGVRARLRAAGDGALRAGIDMAQQLVGEIRSRYAGAYLMP
SFGRFEVVAEVLDVLR
>A0A829TPS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. JCM 18905|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSAKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKATTGLVAAPHLTCIDATREELINIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRAAVGA
>A0A060H9D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylella fastidiosa subsp. sandyi Ann-1|TrEMBL
MIPISFEFYPPKNDDQRAQLDRTANRLRAFAPEYVSCTFGAGGSTLSYTSETVRHLSQHH
GFDTAPHLSCVGGSRQEIRELLKLYRAIGCQRIVALRGDLPSGMGHPGDLRYAADLITFI
RAEHGDHFHLEIGAYPETHPQASNTLNDLHYFKAKADAGADAAITQYFYNPDAYFHFVDA
VQRLGVTIPIVAGVMPISNFDQLRHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVV
TALCERLIAGGAPGLHFYTLNLAKPSTQVLQRLGY
>A0A4U9KRM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium daejeonense|TrEMBL
MKIVDHIKNAKGKTLYSFELLPPAKGQGIQSIFQTMDELMEFKPPFIDVTYHREDYLYKQ
HANGLLERVSYRKRPGTVAICAAIMSKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTPGGHAYATDLLRQVVDMNEGSYLHEDIGSSEKTNFCIGVAGY
PEKHFESPNFNTDFKWLKKKVEMGAEFIVTQMFFNVENIKSS
>A0A139SU59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ventosimonas gracilis|TrEMBL
MTAINPRYSFEFFPAKSESGHANLLQAAQQLTVYQPEFFSCTYGAGGSTRERTLDTVLQL
SAKLGVPSAPHLSCIGSSKAELREFLWHYKALGIRHLVALRGDLPSGMGSSFGELHYARD
LVELIRDECGDYFHIEVAAYPEMHPQAQHFEADLKHFADKVKAGANGAITQYFFNADSYF
YFVERAQKLGVHIPIIPGIMPITNHSKLARFSDACGAELPRWMRKQLEAYGDDLTSIQHY
GEQVVSALCERLLAGGAPGLHFYTLNHAEAPMAILNNLRIKTSA
>A0A552XES8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYLDKTQVIEILERLREKQTMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGADKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>D5W698|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia atlantica|TrEMBL
MNPIELSFEFFPPKTQEGIDKLRATRAELVSLKPKFVSVTFGAGGSTQQGTLDTVIDMAK
EGLEAAPHLSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARQLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCQRLVDANVPGLHFYTLNAATSTKAICERLAV
>D2SA96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / KCC A-0152 / KCTC 9177 / NBRC 13315 / NRRL B-3577 / G-20)|TrEMBL
MSRTVRELLDEGRPTWSFEFFPPKTPDGATQLWTALRELERLQPSFVSVTYGAGGSTREG
TVSVTERIATETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WVAHPEGLQYAAELVELIRSMGDFSVGVAAFPERHPRSPDFETDVAMFVRKCRAGADFAI
TQMFFRAEDYLRMRDRVAATGCEVPIIAGVMPVTNARQITRIVQLSGQAFPEQLAARFAE
LDGDTPEAKAAVRAYGVEIATELCRTLLAEGVPGIHFITMNRSTATREVHANLAAVGSPH
>A0A0J1BKU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula islandica|TrEMBL
MQRAFLQHISSFVICLMTLASVYQSSGCAISFELFPPKNAEGVDLLCKNVERLMQFSPKY
FTCTYGAGGSSRGTTLEVLQKVKQITNLPVASHLTCVGSTVEELEGYLADAREIGVDYIV
ALRGDPPQGTTKFEVTEGGLKYANELVELIRGKFDDLGIAVAGYPETHQEAVDFQTDLVN
LKRKVDAGADIVITQLFYHNDDFYRFRDACQAIGIEVPIVPGILPVTNFKQAKRIASMCK
ASIPAELESAMSEKEDAAHQFRVGVDHARQQTIDLLKHGVPGIHYYVLNKSEAAAELLDG
LQLAGV
>A0A2I1D217|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus campestris IBT 28561|TrEMBL
MEKITDKIAALPPDENYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
ATRSLELAEVCQRQLQLTTCLHLTCTNTSRELVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAIDLVRYIRQQYGDYFCVGVAAYPEGHPVDSFQDTQDPERDLPYL
VEKTRAGADFIMTQLTYDVDAYVNFENRLRTHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVHIPPPIIRKMEEVRFDDDAVKRIGVDVLTELVGGIRKIPRPAQRGFHFYTLNLEKT
VSFIIERCGLIPEYADDSDALVDGGSLSALDLSAAGPNGASRSASRRRRSSLNSLPHNRV
IVDRPQFAESSRSSMTHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLKVTPAVARRVWGYPASRDDISALFRRHVSDELYIVPWSEGGA
EENSSGLSPETATIRPELLQLIDKKGWWTLASQPAVNGRRSDDPVFGWGPPGEGFVFQKP
FVEFFCPNSDYTTVVKPLLQKHGHEKLAWFAVNSKGDFQSSMPSQSSEADPIEINPENVN
AVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIHPRGSATERFLNDTKNDVWL
VCVVGQDFGAGTKVGSKEEQEERSWMWRELIES
>A0A5C8VQT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. WL7|TrEMBL
MRRPAHRASRDGYHPIRVSIEFFPPKTDEMEKVLWSSIERLAPLQPKFVSVTYGAGGSTR
ERTHNTVARMIRETTLKPAAHLTCVDASREEIDAVVQSYWDVGVRHIVALRGDPADGVGH
AYRPHPEGYATTAELVAGIKRIGDFKVSVSAYPEKHPEAATLDADIDALKAKVDAGADQA
ITQFFFENEVYLRYLEKVRAAGITIPIIPGILTVQNFKQSANFARRTGASVPYWLAARFE
GLDNDVETRRLVAAAVAAEQVLDLVDEGVQDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AEKAAA
>A0A3S1I683|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M5C.F.Cr.IN.023.01.1.1|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A3N7BK48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. KBW05|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKQAGIKRIVALRGDLPSGMGIASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A4V3HVT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides franklinii|TrEMBL
MTTHPLDRDGPVAELQDPGSIADRLAAVQPGEVPFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYATELVQLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVIAADPEQGAKPIIPGLMPITSLRSV
RRQVELSSSTLPAALEERLLRAAGDGPDEDRDEVRKVGVEVTTAMAARLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A102ET75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. RF2-non_BP3|TrEMBL
MKSIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDNLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAATATRTICERLAM
>A0A2S9SSZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter cryaerophilus|TrEMBL
MFETLISKLQEDKYLTLETTPQHEPSMHNIVEKIKKFKIDSKVDGFTCTDNPLAKLKYNS
LFAALKLQTEFKKPVIATMTMRDRNKIALQSDLLGANDFDIRAILAITGDPANMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFAVVNAYAKNFGSLEKKMHLKI
QNGAVGIITQPVFDIENVKKLLENFENAKENVEGDKRKAQLILGVFPITKLRTALFLSAQ
VPGIHVPQFWIDELERAHSISEEEEYKVGMHLSKNLFKEINKIHPKIHLMTANNKFEVAS
EILD
>A0A366K8D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium aemilianum|TrEMBL
MHNPIFSLEVFPPKRDAPVGTIYDTLDGLSGLMPDFISVTYGTGKSADRTATARISNTIR
KDYGLPAVAHLTAQYIDKAQADEALNMFEQAGVSAVLPLRGDPVPGREPAGVFDYASDLI
SYIKQTRPQMTIFAACYPECHPQAENLDQDILFLKKKVDSGASHLISQLFYDNEDFYRFL
DKARAAGIDVPIEAGIMPVTNEGQVRRMVKSCASRVPERLETMLERWGSDSAVLKEAGIV
YASDQVADLVAHGVDGIHLYSMNKAAVTRRIWENVGDLFEDEDSTVSDKDLANQA
>A0A3R6P6U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF17-2|TrEMBL
MKLKEYIQTKRIIADGAFGTYYISLYGDGSRAENGAGLSNLPELANIKAPERVIGIHTEY
IEAGAQFVRTNTFASNTKSLSADMEKVKENIRAAVMCAKMAAGKVDREIYLAGDIGPIPV
EGMLHSDRLTQEYIAIGETLLSQGIDILLFETFPELETILPAVTYLKENHDCTILVHFSV
NQFGYSNTGLSAKRLIAEANACPYIDGTGLNCGVGPGHMEKLIRKIVPDDTTFLSVFPNS
GYPKYLNNRLTFTDNAEYFTEKMEEIAALDVGIFGGCCGTTPEYIRRIAAGISADHPVRK
TETEAEKITVSEHPAYGFMERRVKEPAHKLIAVELVPPLNANDEKLLDAAHILKNAEVDV
VTFPDSPSGRTRADSVLMAEKIRLETGLCVMPHICCRDKNAIAIRSTILGSSLNHITNFL
LLTGDPVPVLFRQTTKSVFNFDSVGMMKIVQEMNSDTFTDHPVTYGGAINHNRMNTKAET
ERIRRKMAAGATFFMTQPIFSAEQADVIRQMKKETGATILVGLMPLVSRKNAVFMKNEMT
GIEIPDTIIERYREDMSREEGEACGVQIAREFMAVTDDFADGYYFSFPFNRVHMLKKILK
>A0A1L9B6Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cystobacter ferrugineus|TrEMBL
MKIRNRLNPSNPCFSFEFFPPKTDAGTASLLQTLEDLAQLEPGFVSVTYGAGGSTRDRTV
ELVTRIKRDTGIEAMAHLACLGHTREELRELLRRLEEAGIDNVLVLRGDVPQGASPSTLA
DSDFRHAADLVRFIREEDFNFSLGGACYPEGHVETRSRDEDLLHLKAKVDAGLDFVITQL
FFDNAFYFDFVERARRVGINVPIVPGIMPITNHEQIQRFTRMCGATIPMRLALQLEQLKD
QPEALVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRART
>A0A7D7MCC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus maritimus|TrEMBL
MMLLDELNKRMLTADGAMGTLLYSYGIEYCNEELNIQRPEVIEKIHRDYIAAGADIIQTN
TYGANAHKLARYGLEDQVKAINKAAIAIANKAAKDGGQFVLGTIGGIRGIRQSDATLDEI
VAMVDQQAQHLLSGDPDGLLLETYYDFEELAATVTHLKKLTDAPLIAQLSMHEPGILQNG
MSLNEGLKRLDALGTEIVGVNCRLGPHHTIQAFEGVELPEKAFLSAYPNASLLDIEDGRI
VYESEADYFGRAALLLREEGVRLIGGCCGTTPKHIEAVKKRIGHLQPITEKKVEEKKPIV
IREAEALKDKPLHEKAKTERTIIVELDTPRHLEIDKFLEGSKALDAEGIDAITMADNSLA
SPRISNMAMGSILKHQQDVRPLAHITCRDRNVIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSLELIQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVVERAVAR
LEKKIEAGADYFISQPVYTKEKIIEIHEATKHLETPIFLGVMPLTSIRSADFLHNEVPGI
KLSEEALDRMRACGDDKEKATAEGIQIAKELIDTAAELFHGIYLITPFVRYDMTVELIRY
IRQLDLEKASDRAYA
>A0A2T0VMC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas ventosae|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGKFAITSEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGANCHMSSVSVCSLLTRVGYATILQISCRDRNRIAMQGEILGGAAMGAC
NLLCLTGDGVQAGDHPEAKPVFDLDSISLLQVARNMRDEQRFESGRRIETPPRIFLGAAE
NPFVPPLDWRPLRLAKKVAAGAQFIQTQYCFDIERLRDFMLKVNDLGLLEGPDRVFILPG
IGPLASARSARWIRANVPGVHIPDAVIARLEGAKDQKEEGKRLCMDLLHEIREIPGVSGA
HIMAYRQEHSVAEIIEATGVLEGRVPWYPGRDDPKALNPESPEALSL
>A0A8I1K4H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas psychrophila|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDINNFVRKAHAGADSAITQYFFNADSYFR
FVERVEAAGVMIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A0J5VEH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus firmus|TrEMBL
MSFLDKLKNEIIIADGAMGTLLYSYGTDSCFEELNLSQSEQIQHIHEAYIGAGAELIQTN
TYAANYLKLQRYGLEDSVKEINSAAARIAKKAAAGRAYVAGTIGGIRGFKPNMITLEEIK
RSFREQLYCLLLEDVDGILLETYYDLEELETVLAIARKETDLPIIAQVSLQEAGVLQNQT
PIAEALTKLDGMGADVVGINCRLGPHHMLKTLESVPLPKHAHLSAYPNASIPAYTDGKFH
YEGDAEYFRQSAIEFRNQGVRLLGGCCGTTPDHIKAFADVLKGLPPIEEKEIKAVNKIIV
SEKPESSRELPPLQDIVRERPSVIVELDPPRKLDTARFFEGAKALKGAGIDSITLADNSL
ASPRVCNSALGYLVKQQTGLRPLVHVTCRDRNIIGLQSHLMGLHALGLNDILAVTGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSFSGKDLGQKAAFSVAGAFNPNVRSLEKAVG
RLEKKLEHGADYFISQPVFSEEKLLEVHEAVKDLKAPVYIGLMPLTGSRNAEFLHNEVPG
IKISDSIRSRMASLKDDPARAGAEGIAIAKSLIDAAAELFNGIYLITPFMRYEMTVELSN
YARETTERLSRRKQHV
>A0A150N3Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parageobacillus toebii|TrEMBL
MGLLEDLQERIVIADGAMGTLLYSHGVDRCFEELNLSKPEDIIHIHEAYIAAGAEVIQTN
TYGANYVKLARYGLEDEVPSINRAAVRLAKQAAKNNAYVLGTIGGLRSINKSAVSIDEIK
RTFREQLFVLLNEDVDGLLLETYYDLEELQTVLAIARKETDKPIIAHVTLHEVGVLQDGT
PLAEALAQLEQLGADVVGLNCRLGPYHMIRSLEEVPLPAKAFLSAYPNASLPDYRDGRLV
YETNTDYFKETALAFREQGVRLIGGCCGTTPKHIEAMANALTDRTPIKEKVVKQRDVAIS
VQTNEPNAAPPLQDIVRKRRSVIVELDPPKKLGIAKFLEGAKALKEANIDALTLADNSLA
TPRISNMALGSIVKEQLGIRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVER
LEKKIQCGAHYFITQPLYSEQQIEEVYEATKHLETPIYIGIMPLVSARNADFLHHEVPGI
TLSDEIRSRMAACANNPVQSAREGIAIAKSLIDAAFDLFNGIYLITPFLRYEMTVELVRY
IHEKEQAAQERKVLHG
>A0A1Z7Z3A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium 34_180_T64|TrEMBL
MKVIEHIKKANGNTQFSFEILPPLKGQHIQSIFDNINPLMEFNPPFIDVTYHREEYVYKE
LENGLLRKQVVKKRPGTVGICAAVQNKYNVDAIPHILCGGFTREDTENFLIDLDFLGIDN
VMALRGDAVKNETYFTAEKEGHAYASELVSQIQELNTGNYLDEELLNTSATNFCVGVAGY
PEKHMEAPSLDSDIHFLKKKIENGAEYIVTQMFFDNQKYFDFVYKCRQAGITVPIIPGLK
PIATKKQLNLIPHRFHVDLPENLISAIMKCKDNSQVRQVGIEWCIQQSKELQKAGIPVLH
YYSMGKSDNIKSIASKVF
>A0A1M6AN25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter daecheongensis DSM 21074|TrEMBL
MKVTDHLTRAAGRTLFSFEVLPPKKGENIHTLFSHIEPLLEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLNFLGIDN
VLALRGDPIKSEGYFKPEPDGHSYACDLIGQVANLNKGEYLDEGQDDTWATDFCIGTAGY
PEKHFESPNYAADLRHLKHKVDRGADYIVTQMFFDNEQYFSFERRCREAGILVPIIPGLK
PLTTKSQLTMLPRSFYLNLPEELAEAVRLCPDNEAARQIGIEWCINQSRELMAHGVPCLH
YYSMGKSESIRRVAAALF
>A0A2G5EVJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquilegia coerulea|TrEMBL
MKVIEKIREAEAENRVVFSFEFFPPKTDDGVDNLFDRMDRMVQHNPSFCDITWGAGGTTA
DLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQDK
FVQIEGGFACALDLVKHMRGKYGDYFGITVAGYPEAHPEVIDSSGVATLEAYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPIGNYKGFMRMIGFCKTR
IPAELTAALEPIKDNEEAVKKFGIDFGTEMCKKILAHGIKQLHLYTLNMDKSALAILQIS
RPLPWRRPTNIYRVKEDVRPIFWANRPKSYLTRTIGWDQYPHGRWSDSGNPSYGALTDYQ
FMRPRSRDKKLQEEWAVPLKSVEDIHERFAQFCLGKLKSSPWSELDGLQPETKIINEQLE
NINLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFCSQDQLTALLGKCKDF
PSLTYLAVDKKGNSMSNVAPTDVNAVTWGVFPAKEIIQPTIVDPASFKVWKDEAFEIWTK
VWAHMYPEDDSSKSLLEKIQSSYFLVSLVDNDYINGDLFAAFKEL
>A0A318UAN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter nutrimenti|TrEMBL
MKITEHIKNAKGKTLFSFELLPPVKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HSNGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDSSFIPTPEGHSFASDLVQHVADMNKGRYLHEDMDDPEKTDFCIGVAGY
PEKHFEAPNLDTDFKYLKLKVDLGAEFIVTQMFYDNSKYKQFVEKCRENGIHVPIIPGLK
PITSSKQLVSLPKTFHLDIPLELSEAITACSSEKEVREVGIEWMIEQCRGLKELGAPVLH
FYTMGNSGPTKRIAQAIF
>A0A1F3P626|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium RBG_19FT_COMBO_42_7|TrEMBL
MSVIDKIRNAKSTLFTFELLPPLKGHSIERIYSTIEKLIEFNPAYINFTSHRNETIYRER
PDGLLEKRVVRKRPGTIALAAAVKYKYNIPVVPHVLCGGFTKEETENVLIEMNFLGIDDV
LALRGDPQKGSRTFIPEKDGHSHTWELVRQIVNMNNGKYLEESLEDTAPTSFCIGVAGYP
EKHFEAPNRQVDMENLKRKVESGASYIVTQMFFDNQKFFGFREECRNIGINVPLIAGIKP
VSALNDINLLPQTFHIDMPHELVMALKKCQTDKDAREVGIEWAAMQSKQLIKEGVPGIHY
YTLGRSDNVARIVNAAF
>A0A543IHP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura hallensis|TrEMBL
MRRLSAHRPPTVRELLASGGRSFSFEFFPPKTEKGALNLWRTIRELESLRPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVDHSRAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPDGVEYAADLVRMIRSYGDFCVGVAAFPYKHPRSPDVESDTRYFVEKCRA
GADYAITQMFFRAEDYFRLRDRVEAAGCDVPILPGIMPVTQMSTIERSEQLSGAPFPPEV
RARFDAVADDPEAVRRLGVEHAAELCRELLDQDAPGIHFITFNKSTATREVYGLLDPASY
GGSGSAPPMTA
>A0A285NTT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenobacter hydrogenophilus|TrEMBL
MKIGEILRSGTFSVSFEFFPPKTEEGERELFETIRNLEHISPTFVSVTYGAGGSTRDRTK
RVVEKIHRETNLTVMAHLTCIAHSKQEILNILEEYRNIGIENILALRGDMPKNLEPPADA
CKYAYELVMLIRENFKEAFSIGVASYPEGHPESPNMEWEIRYFKKKVSAGADFSITQMFF
VNEYYYRFVELCQKEGVYIPIIPGIMPITNFKQVSKFASMCGATIPDELIKKLEPYADNQ
EETTKIGVEFAIRQCEDLLENGVPGLHFYTLNKSKATIQIYEAIKDRIEALRKVEL
>A0A4Y8HM05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. URIL14HWK12:I1|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SQVQVPAAPHLSCVGDTKAELRALLAEYKQVGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEADLANFAHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEELLQGGAPSLHFYTLNQAEPSMAIWNNLQPSR
>A0A1B7P8R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emergomyces africanus|TrEMBL
MEKISNKIAALPRDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTIAWRSSTKRRYNIDGEDDSNKDFTHAVDLVKYIRRT
HGDYFCIGVAAYPEGHSDESYPEAQDPARDLPYLVEKTRAGADFIMTQLTYNLEAYKRFE
DMLRNHESGVFRTIPIIAGLMPIQSYHILTRTTKLSHASVPPDIMARVEEVKSDDEAVKR
IGVDILCEIVNGIKKIPSPGPRGLHFYTLNLEKAVAFTVEKCNLIPTSSEPSSDSDTDLD
AAVFTAQGKQNGVTLISRRRASSLNSQPHNRLIVDRPSDFGGSSQTSTTHETQALGAGMP
ALNPPRRTHALQISEGVGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLKVNATVAR
RLWGYPTTKQDINNIFRRHVSGELHIVPWSEGGAQDTGGLNAETATIRNELLQLINGRGW
WTLASQPAVNGLRNDHPIFGWGPRGEGFVFQKAFVEFFCPAHDFKTILKPLFESHGHDEL
TWFATNAAGDFQSSSPPADATTDNYSGPVDVFLDSNATSSNNGVNAVTWGVFKGKEIVTP
TIIEEVSFRAWGDEAFRIWDEWRRIFPRGSPTEKLLHQLKNDVWLVCVVGQKYGAGCGSQ
KAAEAEGGLLWRLLGGTDTETDSANPQ
>A0A1V5JN09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.BinA012|TrEMBL
MAVFTPLRRWQPAFRPFSRQSAGKRLLALTERIIKGPLFGCRMCGNCLLQETAFICHMAC
PKGIRNGPCGGVNNGYCYVDPSRRCAWNLIYERSRGMHREHKLLEVLPPVDWEKAGTETW
GEVVRTARKTGIRNIFVPSRRKGQTMGSVLEESIFKPIRQPDWWKGDSEYHPPAVSGPQS
SLETELRSGRFVITAEVTPPLTASTVKLREKILMVMPYVSAVNFTDGSSAVPRMSGAACS
AVAASLGADPVMQISARDNNRNSLQSMAIGANAQGVYNILCLSGDSPRVGRAPWCSMNII
DVDSVQMLWILRRMRDEGIYLDGREIKNRPKLFLGAAAAPFALDPAMQAIRIRKKVNAGA
QFIQTNLVFDPDRLDPWLEQLEKENLLDKVFILVGISPIKSLSVARYLNENIPGVTVPER
VMQRLADAGDRFTGESIDITVETLLKLKSKKGISGVHIMPLGWEDAIPLIIKKAAHETTD
FKGAGQGRQS
>A0A7X7E2E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp|TrEMBL
MKSFSIEIVPRTWDYLTEQFSAISSTFPLIDTLNVPDLLRFDIRSWEACSKAKPYFKTVI
PHLRAIDFDLKTGFSLLQYLKEHAIQNVLVITGDKPQEMNRKIYRNTSCELIRLIKKELP
AIKIYSSIDQYRSGIRDEIDYVHDKLEAGADGFFTQPFFDLNFLKMYVDILAGTEVYWGI
SPVTSIQSKMYWESKNNAVFPSGFEPSLDWNINFAQRTIDILESVPSNVYFMPIRVSAVE
YLGKVLNPKF
>A0A847HJW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Riflebacteria bacterium|TrEMBL
MCPNLNTGEKQLQDFREFAEKNLVIFDGAMGTRLYEKGVYINRVYDELNLSQPALIQEVH
REYLAAGAMVLETNSFGANRFKLEPHGLADKLEVINFQAAKLAREAAGNNAWVAGSIGPL
GIRIEPWGKTSIEEAEEAFTEQARGLLAGGVDIFILETFFDLNEIHQAIKAVRKLTDKPI
IASMTINEDGNALYGTTVDVFTPKLESWGADFIGLNCSVGPKTMYDAIEKMRSLTSLNLI
AQPNAGLPKVVDGRMIYLCNPEYFGEYARRFFQLGVRMVGGCCCTTPEHIKWVANSAKAL
SPGGKGAILQQFRQVDNVEAQVEVVALPQKSALGRKLAEKKFVVTAELTPPKGCDPEQVI
QRAKQLKEAGIDAINIPDGPRASARLSPLAMSLLIEQKVGIETILHYCCRDRNILGIQSD
LLGAYAIGLRNILAITGDPPKVGNYPQATAVFDIDSIGLVNVIHRLNHGRDLGNNAIGKP
TAFVCGVGANPGAIDLDLEVSRFEWKVDAGAEYAITQPVFDIELLERFLDRISHVRIPVF
AGIWPLASLKNAEFMNNEVPGASVPEPLLARMRKADTVEAQREEGIAIAREALERVRKIV
DGVQISVPFGRVENVLKVIEVLG
>A0A847LDC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Riflebacteria bacterium|TrEMBL
MEDFRKFVDENLVAFDGAMGTMLYSRGVFINQVFEELNLSNPTLVQQIHQEYLAAGAMVL
ETNTFGANRFKLTPHGLAEKIETINFQGAKNARHVADGKAYVIGSIGPLGIRIEPWGKTS
VEEAEAAFSEQAAGLLAGGVDGFILETFYDINEIRQAIRAVKKLCDKPVIASMTINEEGC
ALYGTTPDDFTPKLDEWGADIIGLNCSVGPKAMFEAIERMRKLTRKHLIVQPNAGMPRSI
DGRMIYLCSPEYFGEYAKRFIQGGVRLIGGCCGTTPDHIKWVVREIKALESPSRKTFHFP
AAEPARVEQPAPAVAVVAQAEKSDLARKILEKRFVVCAELTPPKGCDPANVIEAARALKE
HGIDAINIPDGPRASARLSPMAMATLIEQQVGIETILHYCCRDRNILGIQSDLLGAYAIG
LRNILCITGDPPKVGNYPEATAVFDIDAIGLTNVVHRLNHGRDLGGNPIGKPTGYFFGVG
VNPGAIDLETEIRRFEWKVDAGAEFAITQPVFDITLLERFLERVAHVRIPVIAGIWPLAS
LKNAEFMNNEVPGASVPEPLMQRMRAAPTTEAQREEGIAIAREALAKVRPLVEGVQISVP
FGRAQIVLKVLEGIPR
>A0A7K6TP47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aegotheles bennettii|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGGESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPTGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVTMCRELLGSGLVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYISGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELMN
>A0A370AAL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus paraplantarum|TrEMBL
MKLKQALQQRILVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIQAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAVTAREHADHPVYILGTIGGLAGDTDATIQQ
ATPATIAASVTEQLTALLATEQLDGILLETYYDLPELLAALKIVKAHTELPVITNVSMLA
AGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPTNVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSSRSIVAHNQ
PTAKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTMIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TAVSTKSISRKLSYGCDYIITQPVYDLANVDALADTLAANHVDVPVFIGVMPLVSRRNAE
FLHHEVHGIRIPQAILDRMAQAERTGHERAMGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVNYVQAKNLIKVQ
>A0A1M4YXA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfacinum infernum DSM 9756|TrEMBL
MKAGSNLEKVLTSGHFAVTGELGPPRGASVEAVEKKAGYLKGMVDSINVTDNQTSVVRMS
SVAVCKLLVDMGLEPNLQMVCRDRNRIAMQSDLLGAYALGIRNVLCLSGDHNKFGDHPQS
KNVFDVDSVQLISIVKKLRDEGKMLSGQECEGVPRFFIGAAANPFGDPFEFRVTRLAKKI
DAGVDFIQTQCIYNMEKFRKYMHIAHEEGLTEKCYIMAGITPLKSVGMARYMAKFVPGLD
VPDYYIERLKGVEKRKQAEEGIKIAVEQIQEIREMPGVAGIHLMAIEWEHKVPEIMEAAG
LLPRPKVD
>A0A6P0M6K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO3G5|TrEMBL
QGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHPDAKSVFDLESVR
LLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFEKKLEAGAEFFQSQ
LICDFDRLEKFMDQIAAGTNKPILAGIFLLKSAKNAKFINKKVPGVNIPDEIIARLAAAD
NQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPLQKSSAVNDLVFK
>A0A2U1F9U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora cinnamomea|TrEMBL
MATVTERIQRGVPTFSVEFFPPKNDEGEATLWRTIRDLEPLDPAFVSVTYGAGGSSRDRT
IRTTGRIATDTTLTAMAHLTAVDASLEDLRQVIGSYLAAGISNVLAIRGDPPGDKDADWV
PHPAGLSYTEELVHMVRRLGDFCVGVAAFPYLHPRSVDEDTDTRYFIQKVKAGAEFAITQ
MFYDADQFLRMRDRIAAAGCEIPIMPGLMPVTTPRSAERGADFSGAPLPAAMLERLEPLA
EDATGYREAGIDLCVELSQRMFDEGVENIHYISMNRSPAVVDVVQRLGIAARPGS
>A0A542IV00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. SLBN-100|TrEMBL
MFPIRIEIIPAEGIVEQVQALVPTTTTLSVTCLPHHGIERTMRTAVELSDLGYTVVPHLA
ARSIRSRAELTGIVRGCDAAGIREVFVVGGDRKQPAGVYDSALPVLEDIAQYSGGMMRAG
VAGYPEGHPLVSPVDLLDGLLAKQHVASHVVTQMCFAAGKIHDFAALLRREGVHLPVWAG
VAGSVPRTKLVALSTQIGVGSSLKFLSRKGPLARKLLSGDRYSPDSLIAGLESQPGNIAG
IHLYSFNSLESVPAAPDQATASALQAALIRGAARDN
>A0A2U1FQL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora cinnamomea|TrEMBL
MEPLDAAAGTATRRALAALLARPRFEVAPVGGVLDAVPDLPAGATVPVTASPTRGVAGTV
AVAEGLAARGFDAVPHLAARSLRDRGELAEHLDRLAAAGVRDVFVVGGDAREPAGTFPDG
LALLRAIEDLGRPPRVGVPSYPDGHHRIASDVLWADLAAKQAHADYTVTQLCFDADLVAA
FVGEARRRGIALPVVAGVPGAVDTARLLRISVRIGVADAARFARSHRAVAGSLLRPGRHR
PDALVGALAGHVAAGDGDLEQLHLYTFNQIEPTVRWLSQARRAAA
>A0A540R8X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium phoceense|TrEMBL
MVPRFSASAPLDLLEQRPARTAQRVALSFEVIPPRHDADDAKIAGLIDTLARFDPDYVAV
TSSRRSGWLEGTAAFIERISYATDMRPLAHLACTAGPTHELEGWIDRLVDSGVRGLLALR
GDLPEGETALPPDHLPHADALVRLIRQRETEQFARFAAGRLAVGVACYPGGHAESASPDE
DLDVLLTKQRLGADFAITQLFFDAEDFLRFQQRARLAGVHIPLIPGIMPMTSLARVHRMS
ELSGVPVPDRLERRLRGDPTAGLELTVQLAGELLRGGAPGLHMYTHNDAELTTTILSEIG
IHP
>A0A1E3HXY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus amylolentus CBS 6039|TrEMBL
MKITDKLHKAEKEGRPFWSFEYFPPRTAQGLQNLFDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVEICQSTIGIETCMHLCCTEMPKEKVEWALKQAKQNGCQNILALRGDPVAGTST
WEPTPGGFMNAIDLVKYIHKNYPGDFCVAVAGFPQGHPESPLTPEGKEQEMKWLKEKVDA
GADFIFTQMFYDTDIFFDWVKRVRAAGITVPIIPGIMPIQNWEKFDKWVQRENIIVPQHF
YDALNPVKGDDEKVRQVGTKLVAEMCRKILDNKEAGIKGLHVYTLNLEKGARMLLQELGF
EGRREQIAPLPWRPSLTPNRRDETIRPIFWANRTRSYISRTEDWDEFPNGRWGDSRSPAY
GDLDGYPVSIGISATEAYNLWGNPTTTTEIYNLFARFCRGELTKLPWSTQPPASETSVIT
DQLTKMNELGYLTINSQPAVDGVASDDKVHGWGPSGGYVYQKAYLEFFVSPELLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIIQPTIVEAVSFVAWKDEAFE
LGLQWANLYPAGSPSRELITKVMNDSYLVNIVANDFRDGLSIFEPFLLDQTPVGKVVEGV
KGVVEGVVEGVKSVVAE
>A0A6B2R2V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID10362|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPTADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A0B1XY59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. A1|TrEMBL
MGLLERLQTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESSVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLDDI
LATVDEQASVLLAGNPDGLLLETYYDFEELTATLNMLRAKTNIPIIAQVSMHEPGVLQNG
MSLNNALHELETLGADIVGVNCRLGPYHTIQAFEGVELPEKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVSEKHAKPAKIEI
VRDAEPAKFEPLHEKVKRERSVIVELDTPRHLEIDGFLEGAKQLYEAGADVVMMADNSLA
SPRISNIAMGALLKSSNGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDVLAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKMEHGADYFISQPVYTKEKIIEIYEATKHLQAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSEDALSRMKACGEDKERATLEGIAIAKELVEVAAQYFNGIYLITPFLRYDVTLELMKY
IEQLDEQKKGVSING
>A0A838HUJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euzebyaceae bacterium|TrEMBL
MTATIRELLATGNPSYSFEFFPPKTDEGERQLWQAIRELEPLRPTFVSVTYGAGGSTRDR
TVRVVQRIATDTSITAMAHLTCVGASREDVRATIGEIKAAGIRNVLALRGDMPGGPAETW
EAHLDGLRHAEDLVRLLHEEGDFCVGVAAFPEGHPASPDRDADVGYLARKCAAGADFAVT
QFFFDAADYFRLVATASRVGCEVPIIPGVMPVTNVAQIERFAALSGAAFPPALAARLHAV
GDDQEAVRAIGVDVATDLCRQLLDGGAPGIHFYTLNRSTATREIFARLHRGEA
>A0A7C2HEV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenobaculum sp|TrEMBL
ASELIELITKYFDNEFCIGVAAYPEGHPESPNMEWEIKYFKQKVEKGASFAITQMFFDNS
YYYEFLDLCRKANIDIPIIPGIMPITNIKQISKFASMCGATIPSYITDALENLSEEDVVK
KGVEIAINQCEDLIKNGVKHIHFYTLNKSKATLDILKAINL
>A0A6N0LB08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 10FS3-1|TrEMBL
MLNFSQYLSKNQFCILLEYLTTSQDTAVPQSLAGYPVVTTLADRVHADDDLAPLEVAKSF
PSHIEKLLHYSGKGRDIQDFEMFLQRAQKANIQNLLLLTGDKLKNHSDGCDGSSRTRYLE
SVNAVMVANKHGGFHIGVAFNPFKYAEAERDAQYLKLHKKLKAGAGFIITQLGYDIDALK
QAKAFLKHHHYPQKMLVCVMPLSFARANFMLKNKVAGIVITPHMLQVLSEEKQAGLQENA
YKRCALQILICKQLGFAGVHLSACHKPEEQILLESYIEQYQHLDLEALEDIWNSLWQVKT
GKEFVPELPYYSRQPTSTQLIKYQHLHFMHETLFESKIAKGIGGFIFKASFWENKSVAKA
LLQTEFISKHGVVGCESCGQCRLADTLYICPETCPKGLANGPCGGTCLDRCEFGDRECIH
SVKARLAKAIGQTELLKQQLIPTVPIEVRGTSSWKNWYLATEA
>A0A3M8K6L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium alimapuense|TrEMBL
MNAPMPRHRANSRFSASAPLDSFDNEDTVGFSAPRATAPRRTALSFEVMPPRRNADQEAI
SELLTTLESYNPDYVSVTSSQNSGWLEGTAEFISKISATTRMRTLAHLACTAGTREELIG
WINRLMDAGVRGLLALRGDFAEGQHELPQGYLAHADQLVRLIRELEGNQAARFGAGRLAI
GVAAYPSGHAESLNLDQDIDVLLAKQRCGADFAITQLFFDAEDYLRFQERARLAGVRIPL
IPGIMPMTSVRRLHRMGQLSGLTVPDRLIRQLEEVGPEGEHQTGLDLTAELAQTVLDAGA
GGLHVYTFNRSDVTEQLLSRIGIAPQLQS
>A0A357LWK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillales bacterium|TrEMBL
YGAGGSTRDRTYAIVKAIQERGIPAAPHLSCVGDSKEDLRQLLNEYKDLGIDRIVALRGD
LPSGSGLANSELRYANELVEFIRAETGDHFTLEVAAYPEMHPQATSFEKDLQNFVRKVKA
GADSAITQYFFNADSYFHFVDRVRAMGVDIPIIPGIMPITNYSKLARFSDACGAEIPRWI
RKQLEAYGDDSQSIQQFGEDVVTDMCRRLLDGGAPGIHFYTLNQAEASLRVWRNLV
>A0A409WA58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panaeolus cyanescens|TrEMBL
MKLTDQINEKNGSQLEPFYTFEFFPPRTDQGFENLMSRISRLATLNPLAMSVTWGAGGST
KDRSLELAGLIQSQQWNTILHLTCTNMEQGLVDYVLKDSKEKGIRNILALRGDPPRGEEE
WVASDSRFTRAVDLVSYIRSIPEYADWFCIGVAAYPDGHGDGLFDEETEIEHLKQKLDAG
ADFIITQLFYDVDHFLRINVPVIPGIMPIQTYGSFARVTKLCGTRVPDAIAAQLAEISHD
DQVVKEYGITLAVEMTRRLREEGAIPGFHFCTLNLEKSVQRVLEKLSWAGPINPLQNKLI
AEASEISTSHGGPAETDLVVSASAAVNEATMNLSTSIITENEVGRGELNNAASWDDFPNG
RFGDFKSPAFGNQDMWGGSGISRSEALTQWGHPNTVDDLTQIFLDHLHSKISTTPFSPTP
LSAETLTILPHLERLTKGGWWTVGSQPAVDGVSSTDEVFGWGPRAGYIFQKGFVEFFCEE
RDVEKVINRIDDKGKGWVHYFAGNVKGECRTNVPEDGRNAVTWGVFPGQEIVQTTIIERE
SFLSWLDEAFSIWSEWASFYRPDSPHRRLLEGVRDSRWLVSVVHHDYKNADALWKVVLDG
NEP
>V4FHW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp. ME-1|TrEMBL
MRENLFKEALLNPSVFPVTWELVPGRGAKESAQEKTLSLAKQAAESGKICALTLTDNPGG
TPAMSADFMGSEIVNLGIEPLVHFTCKDKNRNQIESQLYALDRAGVRNLLVMSGDYPVSG
YRGRPAPVFDLDPIHTLQLISDMNKGLTYPGVKGNIRHQPSIFFVGAVVSPFKATEAEQL
LQYYKLKKKIDAGAQFIVTQLGYDARKFHEALLFMKQNNFNLPIIGNIYILPYGAAKMMN
RNELPGSVVTDKLLAEIDKERNDSDKGESARILRAARMYAILKGMGYSGVHIGGHNIKHE
QVERIITQGEALASQWRDLIRYFDYPIPGGFYYFDNDSQTGLNLDKPTNRQSRPLDATVG
FTYGFSRFFHNLMFEPEKKLYSLMKKLSGKVTGTKIESIFHKLEHWTKVVIFDCKDCGDC
ALIDVAYLCPMSQCPKNQRNGACGGSFEGWCEVYPGKKKCVYVRAYARLKKHQEEAQLSK
NIVEPCNWDFHQTSSWLNFYLGKDHTSKRHSGNSSGN
>A0A0D2J686|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dethiosulfatarculus sandiegensis|TrEMBL
MRTFKEVLESGEFVITAEAAPPKGVNLEKMKHHIELLRDKVHAVNITDHQSSVMRYPSLG
GALLAREMGAEPILQMTCRDRNRLALQADLLFAASRGVNNVLCLTGDSVVVGDHKEAKGV
FDLESSQLVRTVKNLQKGYDMAGNRLDGAVDFCVGAIVTPEADPLEPQKIKFEKKIESGA
EFIQTQAIYDMEKFKSFMDYAHGFNVKILAGIILLTSAGMARFMNKNVPGVLVPESLIKE
MAEAPKGHALATGIKIAGRMVKQLKEENLCHGVHIMAIGKEELVPEILAAAEVSI
>A0A3D1Y172|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillales bacterium|TrEMBL
MTTLSFEFFPTKTEEGTEKLLKVRDELAAFNPEFFSVTYGAGGSTRDRTYAIVKAIQERG
IAAAPHLSCVGDSKDDLRSLLNEYKDLGINRIVTLRGDLPSGAGLASSELRYANELVEFI
REETGDHFTLEVAAYPEMHPQATSFEKDLEHFVNKVKAGADSAITQYFFNADSYFNFVDR
VRDMGVDIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDNNESIQQFGEEVV
TEMCHRLLEGGAPGIHFYTLNQSEASLRVWRNLV
>A0A0A8B4G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Berryella intestinalis|TrEMBL
MRITQVFENAKPVSFEVFPPKGQLTVDAARSVIAELAPLRPGFVSVTYSAGGSGNTALTE
QVAHIGQTEFGLNMMAHLTCTGASTEDILRHIDSLRARGVENVLALRGDAVEGARPGDFA
LARDLIPVLREAGFCVGAAAYPEGHIDCLDDYENIRHLKEKQDAGAQFFVTQLFFDNDFA
YRFLDRARSANVTAPITFGIMPFLSKSQVTRMVFMCGASMPAPLVKLLARYENDPASLRQ
AGVEYACRQIDELARFGVDGIHVYTMNQPDIARAAVAAATPFFAR
>A0A1G6JUK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter marinus|TrEMBL
MSKRTPISFEFFPTKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIADFN
GKGTPVAPHLSCIGDDKARIAELLEIYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADNFDNDVKRFVEKVNAGADAAITQLFFNPDAYFYFR
DSVEKAGVNIPIAPGIMPITNASSLIRFADSTGADIPRWIRKQLAAYGDDSKSIQAFGHE
VVFKLCERLISGGAPSLHFYSMNHTEPTRQLVVDLGLN
>A0A084SZ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Archangium violaceum Cb vi76|TrEMBL
MKIRNRLNPSNPCFSFEFFPPKTDEGTANLLKTLEELAPLEPGFVSVTYGAGGSTRDRTV
ELVTRIKRETGIEAMAHITCVGHTPGELRDVLQRLKDAKVENVLVLRGDPPQGQTAFEPV
PGGFRHATELVRFIRDEDFNFCLGGACYPEGHVETASRDDDLRHLKEKVDAGLDFVITQL
FFDNAFYFDFVERARRIGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLGLQLERVKD
QPEALVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRART
>D4ZCG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella violacea (strain JCM 10179 / CIP 106290 / LMG 19151 / DSS12)|TrEMBL
MGFHHAQHSTSLNQSLAELNGDINVSFEFFPPASPEMETILWNSIRRLEPLKPKFVSVTY
GANSGVRDRTHGVIERIQRETDLVAAPHLTLVDASDEELKELAKHYWNSGIRDIVALRGD
LPDGSPRPTRFANDLVRLLRSVADFDISVAAYPEVHPDATNAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVTNFKQLKRFAGMTNVSIPGWLHKQFD
GLDDDPATRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A0S2TG28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Tenderia electrophaga|TrEMBL
MNTQSKFPKQFSCEFFPPKSEKGADKLHNTLEALAKLEPAYFSVTFGAGGSTQEGTFDTV
KEIQEKGYEAAPHLSCIGGTRDSIRALLDKYMSIGVKRIVALRGDLPSGMRDRGDFRYAN
ELVEFIRAETGDQLKLEVAAYPEIHPQAPNAKKDVRNFVRKVKAGANAAITQYFYNVDAY
FYFVDECEKQDVDIPIIPGIMPIINYSQLTRFSDMCGAEIPRWIRKRLESFGDDKASILA
FGEEVVTDLCRKLLDGGAPGLHFYTMNQTAPTEKLWRNLDL
>A0A510KFH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia wadei|TrEMBL
MRIKDLFEKKKHLISFEIFPPNKNFSVEKLKDVTDELVQYKPDFISVTYGAGGKTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEINDYLQEAKKCNIKNILALRGDVPQGETEDIYN
RGDYKYASELISDLRKNSEFNDLSIGGAFYPETHYENNDLVDLFYLKNKVEAGTDFLASQ
MFFDNDIFIKFKEQAEKLDIKVPLIAGIMPVTNAKQIKRIIELSKCSVPEKLDKLLGKYG
DNPESMKKAGIMYASE
>A0A0F4GLE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymoseptoria brevis|TrEMBL
MDKITDKIAALPPNANYFSLEFFPPKTQQGFSNLNARLSRMAHSLRPLFVNVTWGAGGST
SAKSLALAEVTQRELGLTTCLHLTCTNMSRKLIDEALEQAKVLGVRNILALRGDPPRSDE
YRDNSLPNADEDDSNKDFTWAEDLVRYIRKQYGDYFCVGVAGYPEGHSDQSCPEHQSMEH
DLPYLVEKMKAGADFIMTQLFYDVEAYERFEKRLREHESGAFKTVPLIPGLMPVQSYQIL
RRTTKLSHAALPEEMLRRLHAVKGDDEAVKRVGVDILSEMVEGMKSRKGNGPQGFHFYTL
NLEKVVAQIVERTGLIPPEEKKDDNAVADDEVGDFVLVDKDVKQKQRRRKSSMANSQSRN
RVIVARTRASSNSSTRTSAAHEVPDDEAGIPREKINSRSNTLAISEGDGSLGREATWDDF
PNGRFGDARSPAYGEIDGYGVSLHVSVPDAKRLWGEPKTIEDISTSFRRHLSGEIEAIPW
SEEPLQNETLTIKDQLQSLIDRGWWTVASQPAVNGVRSTDPVHGWGPKNGFVFQKPFVEF
FIPASDWSSLQGKLVEHPQITYFAGNANGDFVSSGEDTINPVTWGTFAGKEIITPTIIEA
VSFKAWCEEAFGIWAEWQRVYKPGSESSKLLERIRKEYWLVSVIHHGFLEEGALWTDLLE
A
>A0A7I9WMX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium murale|TrEMBL
MGVCCPKRMDFGPCGGVHPDGSCEMRPGPCAFPEVVPWSGPVADGVPVTAPLVLTDFSAA
PFDPADLVATAELLAPACDAVLVGEHQNRPDFPPTLAGRMLLDSGVSPWITLSCRDRNRI
VLEQELRGLRQVGVQTVFCVTGDGRGYDVRPDVTQTFDLDGPRLLSLAAALGVTAAAPET
PTAPPVTGRPARLVQKQRAGARIAVLNHVPYPAQVAAFMAEARALGLSIPVLAAVAVFTD
SWSAAILEGLPGLELDQEVVAQVINARDPVEAGIAAAVAEARALLAIDGVDGVNLSGSAS
SAGTRVGAQIKAEVGQRIRTEFA
>A0A854NDE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium diphtheriae bv. mitis|TrEMBL
MSAQPLPAAYQRTITDVISMPTPGQVPFSVEFMPPRDEAAEERLWKAAEAFHDLGASFVS
VTYGAGGSSRERTMRVAHKLSRHPLTTLVHLTLVEHTQEELEEILCTYASHGLSNLLALR
GDPPGTDPMAPWVPTAGGLDYAKDLIDLVRKTEQTSHFQVGIASFPEGHYRAPSIEADTQ
FTLEKLRAGAEFSITQMFFDVDHYLRLRDRLVKADPEHGSKPIIPGLMPITSLRSVRRQM
ELAGATLPKALEKRLLDAARGDEEAHRGDIRKVGIEVTTEMAQRLISEGIPDIHFMTMNY
VRATQEVLHNLGMAPAWGTQQGHDAIR
>A0A7J0CZW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces microflavus|TrEMBL
MSGLRELLAAGTRSFSFEFFPARTEAGAAGLWEVVRRIEAFAPSFVSVTYGAGGSSRDRT
VELTNRIAAETTLRPVAHLTAVAHSVAELRHVIGQYADAGVRDVLALRGTRRATRTRPGS
RTRTASPTPGNW
>A0A4W6CQF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lates calcarifer|TrEMBL
MVNQVQRGDGTCQSCKSDSSGASNSGGESSKESSRCSTPVLDSDRSDRLRDKMRRRMESG
DHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAT
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVISQLFFRADTF
LKFLDDCRQIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIQQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLKMWGEELMNEVSVFEVFTCYITAQPNRSGHKVMCLPWNDEPLASETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGRNLTNAPDLQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPDSLNDGTVS
E
>A0A5S4TB48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pyogenes|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLNKVGVQKILDLRGDIIPDVEQQKDFRYATD
LIEFIKEQAPHFDI
>A0A2W6VKE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MTYGPCGGVNADGTCEVVPAPCVFLGRELPVRWAGDASPLADDGAAATAAGREIQQIAGR
RPLVFTGFPVRAMSSDAVAPSADALLGSVDAVLSGDAGRSRVQFPPSYRAALITATGLRL
WMGFNARDRNRTALERELASLRAIGAAGIHCVTGDHTETGDRPDARPVFDLESTTTIPRA
RALGMLTSFAESPAAPPVEARGARVAQKQRAGGQLCLTQYAGDADELAEFVAQCRSAGAT
APVLPGVPLVVDREGAALLDSFHAAKLPSGFIDALFAARDVRAAGIRLAIEYGRALLDTG
IVGGVVIAGGSRPGDEAVYAADLATVARELGGGS
>A0A5B9MJ02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stieleria maiorica|TrEMBL
MSSPIKLADHFHGERCAISFELFPPKTEAGMKLLETNVERLKAFEPSFFTCTYGAGGSTQ
SRTLDVVERVRQMTGLPVASHLTCVGSTVAELRDYLAEARRRGAEYIVALRGDPPKGSES
FQAVEGGLRYGNELVELIRESFPDQFGIAVAGYPEVHQEAPDAQTDLDNLKRKVDAGADI
VVTQLFYDNDDFYRFRDACVAAGIEVPIVPGILPVTNFKQAQRIAGMCKARIPDDMAAAM
NENDDADYQFKVGVDHARVQTIDLIENGVPGIHYYVLNKSDAAAQMLDGLSLGAPSS
>A0A178MFM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexus islandicus|TrEMBL
MHSTLQRRLAAGQTVVTGEIAPPKGAARAHLETLATNIRDYVDAVNLTDNQRGIARMSSL
GGSVILQQLGIEPIMQMTCQHRNRIALQADALSASALGVRNLLAMTGDHPRIGDHPDAKN
VLDLNSFQLIRMLRTLRDQATFQAGTPLKEAPRFFIGSVANPNVERAARLEKKIEAGAEF
VQTQLIFDVNRFRHWMADVRAAGLHQQAYILAGVMILRRPQSAIYLRDHLPGTLMPDPVI
ERMQRAADSEAEGIALAAELVNELLSIEGVAGVHIMSVDWTRAIPRVVEQAGLLPRPPAP
AIEEGVGSRE
>I1CZU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora glauca K62|TrEMBL
MTSHPETTGHRCRGLADLVASMSYEVLPFASTEERVLAEVPTSVPLSITVTEARGLDVTL
DLAERLVRHGYHATPHLAARQFVDQRHLAEVIDRLRSAGVRSVFVIGGDAPEPAGRFADA
GALLRTMRELDHPFDEVGIGGYPEGHAAIPRAALDHAFAVKAPLATRVVTQICFDARTTV
GWAATVAASGVDLAVHIGIPGPVHRRKLARISAGLGLGPSARFLRKQQSLFWRLFLPGGY
RPTSLARDLGAALPAGNVAGLHVFTFNELGETERWRRRLLATTSGTS
>A0A4Q2S836|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides glacieisoli|TrEMBL
MRELLAAGERSFSFEFFPPKDEAGEQQLWQAITDLEPFGPTFVSVTYGAGGTTRDRTVAI
TERIARDTSMLPVAHLTCVGHTTDELTAILDELSAAGVTHVMALRGDPSTGPGTPWTPTE
GGLTYASELVELISARADMRIGVAAFPEGHIDAADLESDARVLKAKHDAGAEFAVTDMVL
RASDYVALVERATAVGADFPIIPGIMPILNLRSMERMVEFSGRQLPEETSARLTPYADDP
VALRAEGIAIATELCEDLLGAGAPGLHFYTLNRSKATREIFANLRITV
>C5M851|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida tropicalis (strain ATCC MYA-3404 / T1)|TrEMBL
MKISEKLDQAHKAAHSPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALDKAYKSGCQNILALRGDPPLD
GSESTGDFKYAKDLIAYIHKKYENHFNIGVAGYPEGHPEETDELKTLEYLKEKCDAGANF
IITQMFYDADNFISWCSKLRKIGIDLPIIPGIMPISTYSAFLRRAKWSEIAIPQHFLDAL
DPIKDDDYLVREKGTELVSEMCQKLLESGYINHLHFYTMNLEKATVMILEKLNLIEAVKS
NEIVGVTELPWRKSLNPERSKESIRPIFWQNRKYSYVTRTATWDEFPNGRWGDSRSPAFG
DIDLCASELLRQSPKRAQELWGLPQTISDITGLVISYLKGQLNSLPWFDGAIGEDTNIIL
DHLIELNENSLITLNSQPSLNSVRSSDKVFGWGPKNGYVYQKQYLEFFCHKDVVARLLDH
IDQYNKNQGDSTSAVISYYAVNKNGNLISNCQDDDINAVTWGVFPGEEILQPTIVEKTSF
LAWKDEVYTLFSEWSKISGMFDAEKDKIQHFNELMSQITENFVLCNLVNNDFLQGNDVLF
DLIKQVVHS
>A0A136K7D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. OLB3|TrEMBL
MNREPRRLKDVLAQGQFAVTVEYNPPKGTNLTHVVESAKALLGRVHGVNVTDNTAAIVRA
GSMPVCRVLYEMGHDPVMQLTCRDRNRIAMQSDLMGAHILGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNQGRDYAGNKLDGATAFTIGGAVTPEADPVGPMLVKFEVKV
RAGAEFFQTQAIYQPDQFKTFMEAVRPFKVKVLAGILLLRNAKMAEFMNANIPGVCVPQT
MIDELRAAGDKHALDAGVEIAVRTIKAVRSFCDGVHIMAIKATDRLPEILAKAELG
>A0A2A3G2F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. ACPA1|TrEMBL
MTFDSVRGRASEGWVTRTPSIVDRIRSSSDGRVPFSVEFSPPRDEAAEARLWRAVREFER
LGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWEKHPDGVEYAEDLVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRFLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSV
RRVLELSGSRLPAHLEKRLATAAGDGPEENRAAVREIGIDVATEMSERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSGVADPAPVTPARVS
>A0A1P8K6Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax saidenbachensis|TrEMBL
MSQTPRLPLSLEFFPPKTPEGAEKLRVVRQQLYGLKPEFCSVTFGAGGSTQEGTFGTVRS
ILAEGVDAASHFSCIGATKDTVRAQLATLKTMGVKRLVALRGDLPSGYGAGGEFHYASDL
VTFIRMETGDDFHIEVAAYPEVHPQAKSPASDLQAFAAKVQAGANSAITQYFYNADAYFR
FVEELDALGLNIAVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQSFGDDVASIKSFG
LDVVTDLCEQLRAGGAPGLHFYTMNQSVATLALCDRLGLATA
>A0A656Y6L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. Root137|TrEMBL
MAEPRTPGLHTATARRAQNANDRPTISFELFPPRNPDAAPRLWATIRELESVHPDFVSVT
YGASGKTRVTTRALVRRLLQETSLNPIAHLTCVGTSREEITTIVGEFLDEGLRSFLALRG
DPPTDQSDWQAHPDGLQTAGELVELLREIEAQRCLDSPSQAVRARVRPLSVAVAAFPRGN
HATGGTRAQDVASLLAKQQAGADFAITQVFFDADDYLGIVAEAREAGVTIPIIPGIIPTT
DPARLLRVQELTGVPVPKDLIDLLGSADDELDRHRRGIRASVDLVNGVLDGGAPGVHLYT
FNQHHAALDLLEGAHLDGGARTAPDLASWPQDTAPARPPRD
>A0A1F1VQZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. HMSC08A09|TrEMBL
MHDNELTGPTAAAGSRSEALSSAETGTARRLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPAGGVTGGGRQGSAHEPETGRCEAPRVRAVQEQTNPSECVLAHV
LDSSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRAEDVAGELRHA
DDLVRVIREVEADFFGDGRRHVTIAVAAYPATNDHIEAIEVLAAKQAAGADMAITQVFYD
AADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSSLGSASGATL
VERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDAV
DRGYLQATPGRGPSFLRRGSARATVSSHHPVQPLTTITKENA
>A0A8J7HB88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobilitalea sibirica|TrEMBL
MQIASLFEQKKTVLSFEVFPPKKTSSIDTIFKTLEELEGLHPDFISVTYGAGGNAGDTST
CDIASVIKHTYKIEPVAHLTCVNYTKDEIDRILDRLKENEIDNILALRGDINPSLSPKKH
FHYASELVSYIKNKGGFHVSGACYPEGHVNAGSLEEDIKFLKMKVDAGAKHLITQLFFDN
KYFYSFLEKVREIGITVPIEAGIMPVVNKAQIERMVTLCGASIPAKLSKMLQRYENTPEA
LKEAGIEYAIEQITDLISRGVDGIHLYTMNNSYIARKISEKVKGLL
>A0A7X7I4M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistaceae bacterium|TrEMBL
MLIRDLLSRTRPAISFEIFPPKPETPIETVFKTVAGLKELSPDFISVTYGAGGSSRDRTV
EIASAVHNRWGLVSLAHLTCMGSSPAEVEKVMEDLEQEGVCNILAMRGDPRPDGGENHFH
HASDLIHHIRRGHFRDFSLGAAAYPEGHPESPSLEEDLLHLKEKVDAGADFLITQLFFDN
EIFFRFMDRIRALGIAVPVLAGIMPVLNARQIGRIVSLCGASIPPRFARIMSRYEHSPEA
LSEAGIAYATEQIIDLLSWGADGIHLYTMNRPDVAKRIMESIATVRRTLNGSSSGV
>U1RWN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces johnsonii F0542|TrEMBL
MIRSTIQSGRETWFDDAAATRCAGASARIDGDDVLDNEPTEPTAAIEGRNDDPGDAERAT
SRSLPTVSLELFPPRAGKAASATWGRIDRLLATGPDFVSVTYRPAFVADPVPGSGEKGRW
QQRDAPRVRAVQEESNPSEGVLAHVLGSSAVPLMAHLTCIGYRKREAVDIITRFLRMGVR
RFLALRGDPPTGTRADDVAGELRHADALVRVIREVEADYFGDGRRHVTIAVAAYPATNDH
IEAIEVLASKQAAGADLAITQVFYDPADYVALTNAASYAGVNIPILPGVIPLTDLGRLTR
LEALTGVKVPDALRSSLGSASGATLVERGIGATLDLATALLRAGAPGLHLYTFNRTRPAL
DVISHLRLGGILAGAAPDREVRDAVDRGYLQATPGRGPSFLRCGSPGAAVSSRHPVQPHT
TITKENA
>A0A1I0BU27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira multiformis|TrEMBL
MESQKKFVPTFSFEFFPPQTAEGIEKLRATRSQLAQLKPKFFSVTFGAGGSTRDRTLETV
LEIQAEGLVAAPHLSCIGATRENIRTMLEQYRSSGIRHLIALRGDLPSGMAQGGEFRYAN
ELVAFIRREYGNAFHIDVASYPEYHPQARTAQEDLKNFKRKIEAGADSAITQYFYNADAY
FDFVDSCEAMGINIPVVPGIMPINRFSQLARFSDTCGAEIPRWIRKRLEGYGDDSASIRA
FGLDVVTDLCARLLNAGAPGLHFYTLNSAGLTTTVWQRLGL
>A0A484HL57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacteraceae bacterium|TrEMBL
MELKSGSNLEKILVNGHFAFTGELGPPQGANSEEVRKKAGYLKGVVDAVNITDNQTAMVR
MSSWAASLIAIQEGVEPNYQMVCRDRNRLAMQSDILGAYALGIRNMLCLSGDHPQFGDHP
QSMGVFDVDSMQLIQMTRKMRDEGKLLSGTELDEAPKMFIGAAANPFAEPYEWRVHRLAK
KIRAGVDFIQTQCIYNMERFRNWIKEANDMGLTEKAYILAGVTPMKSVGMAKYMKSKVPG
MDVPEEIIKRLQGAEKGKVAEEGIKIACEQIEEFKEMEGVHGVHFMAIEWEHKVPEIAER
ANVLPRPQV
>A0A0F5VEZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium halotolerans|TrEMBL
MGYSYASHLDALNQNIADLNGAINVSFEFFPPSTPAMEETLWSSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLLAAPHLTCIDATRDELRAIARDYWKNGIRNIVALRGD
LPPQGGKPDMYAVDLVKLLREEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVVNMNQAKRFAQANNVKIPNWLEKQYQ
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAEAEATA
>A0A0R3CQW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium manausense|TrEMBL
MTETTTPAHTEGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTISRILKETPLLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTPYASHPDGYQNSADLVAGIKKRHADIEVSVSAYPEKHPESRDFDADIDTLKAKVDA
GATRAITQVFFDNDFYFRYLDRVRARGINIPVVPGIMPMHNFKQARNFVTRNGTTVPEWL
AAKFEGLDNDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A4Q8UMU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. S39|TrEMBL
MQSKKCQLSERAMSAEAVARVRLEVAPSADLLTQLPAAFDTTGSVSVTCLPHHGPARTVQ
ASVNLARLGYHTVPHLAARSITGEAELHSLLKQLQEAGVSELFLVAGDRRTPAGPYSWSG
QLLEAVNAYSPDFSIGIAGYPEGHPQLSQEQLRSGLLTKASLASSVVTQMCFSAEAISRY
IRTIRTSGIQLPVWVGVPGPVSVRKLVSLGARLGVGRSLKLARGTGMAGALWRRDDFLSY
DSGRLIRHVHQELAGDPLFAGFHVYTFNDLGRLPGLLDDLRALRPTTPLAPGSTSTRLFP
AKI
>A0A1Y2N805|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia autotrophica|TrEMBL
MSGDCPKRMRYGPCGGVRPDLSCELGTGPCPFAGRPVERWDGPPVRSVLPPALTGPGPMV
LTDLTSSPYDAGALARHTRILAGACDALLIGQHHDAPDFPPTLLAALVREAGGRAWVTLT
CRDRNRVVLEQDVAGLVAAGADAVLCVTGDGRAPGVRPDVTQVFDLDGTRLAAIAAGAGL
AAVVPEAPAAPPVDLRPARLAEKQRAGAGAAVLNHAGSPSQVARFVERARRHGATLPVLA
GVAVFTDEPGARVLQAFPGLELDPGTVRAVLCAPDPVEAGIEAAVDEAVALLAVDGVAGV
NLSGRGSSGDHTAGTEIKAEIGRRIRARVRG
>A0A4Q8UPX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. S39|TrEMBL
MSPPSLIDHHPNLTDAAPVALSYELFPPRSPAAAESLWNTIRELETTDPDYVAVTYGASG
SNRDTALELVHRLVQETTLRPLAHLTCVGNTPQELAEIIGELLDTGVRGILALRGDQPKD
GAQPAAGSLAYAQDLIDLIRRVEQRRSALLCAGKIAVGVAAYPTKHPESPSEEHDIEVLL
AKQRSGADFAITQVFFHSEQYADLVTRARRAGVTIPIIPGVMPLTSLRRVIRLAELAGVE
PAPELLERLAAADNDAERLRIGVRATVDLANAALEAGAPGIHLYTFNEHQSALEVLDKLA
LPRHSRSASRRSAIARRQLAS
>A0A0N0SUC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. AS58|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFYAPKTPKGERSLWNALRRVEAVAPDFVSV
TYGAGGSTRASTVKETEQIVADTTLTPVAHLTAVDHSISELRNVIGQFADAGIRNMLALR
GDPPGDPMGDWVPHPKGVTYAAELVRLIKESGDFCVGVAAFPEMHPRSCDRDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCATPVIPEVMPVTSVRMLERLPQLSNAHL
PSTLKERILTAKDNPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>M4XMH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ATCC 13867|TrEMBL
MSQERRFSFEFFPAKTEAGHEKLLATARQLATYKPDFFSCTYGAGGSTRDRTLTTVLQLD
GDVQVPTAPHLSCVGDTKAELRALLAHYKDAGIRRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGDHFHIEVAAYPEVHPQARNFEDDLANFVRKVKAGADSAITQYFFNADSYFH
FVERAEKLGVSIPVVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDIASIQAFG
EQVITEMCERLLEGGAPGLHFYTLNQAEPSLALWNNLKLPR
>A0A0M6XWK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium aggregatum|TrEMBL
MTDQRLLANGRLPASTEMSPKQVVEKTELLEFIPAGTQVYVTDLGNCSEDMIVDAARILR
DNKLTAVPHMAARRYASLEDFERRITRLTQEAGATEVLAIAGEAEKAGPLTSSVALLETG
LFDKLGIKKIAVAGHPEGAPDIKPDVIKSFLQRKHELARESDAEFRIVTQFGFDPHRVSL
WLDELREWGNEFPVHVGVAGPAKMTTLLKYAAFAGVENSFNFLKKRGGAVVSMLSGYDPD
TMVDPLETRVTSQPNTQLAQIHAYPFGGIQKTAEWLHSRGSWSFQTSSSILTANESA
>A0A484HKC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacteraceae bacterium|TrEMBL
MKTESVLEKVLASGELAVTSECGPPRGARPDVVKAKAEMLRGYVDAVNVTDNQTAMVRMS
SLSACVIIREMGMDPVLQMVSRDRNRLAMQSDIIGAYAHGIHAMLCLSGDHTHFGDHPMA
ANVHDLDSIQSLQMVKKMRDEGKFNGGADIDGPPKMFIGAAANPFADPFELRVARLAKKV
KAGADFIQTQCVYNLDKFETWMQGVRDRGLHEKVAIMPGITPMKTVGMARYMKNRVPGMD
VPDELVDRMAKTPKEKQADEGIKIAVESIERLKEVEGVSGFHIMAIEWEEKVPEIVEKAG
LFPRPEV
>A0A2H5WB60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR12|TrEMBL
MRTSEPRPRALEGLSAEERAAVRRVVAAARFELIPLPSALERAEELPPGAPVTVTASPSR
GIEATLELAAELAARGHPATPHLSARLIRDGAHLAELLARCREAGLREAFVVGGDGDRPG
GFADGLALLRAVHELGSPFERIGVPGYPEGHPGIPPAALRTALLAKAPLAHWVTTQMCFD
PNALAAWIADVRAAGVGLEVHLGVPGVTDLVRLLSISARIGLASSARYLRKNRSLLGRIA
RGRFGPDGLLEALAATLADPRAGVGALHVFTFNQVAPTIAWRARVLGGARGLRSGGSRRG
ARAVPGPPASRAPQRDAHLATSWYRSAPLEARHGLRGTRWGWGDGGRG
>A0A085VBP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae|TrEMBL
MSLDRRYSFEFFPTKTDAGHEKLLNVARQLASYTPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRALLTQYKEAGIKRIVALRGDLPSGMGMASGELRYASDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDIKNFVHKAQAGADSAITQYFFNADSYFY
FVERVRKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EQVITQMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A2D5RYL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rheinheimera sp|TrEMBL
MAFANARYLDAINRNLHDVQGKVNVSFEFFPPKTPQMKQTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKYRTGLIAAPHLTCVDASKDQLVDIARDYWDNGIRHIVALRGD
LPPDSAAIPELYAADLVEILRSVADFDISVAAYPEVHPQAPNAQFDLLNLKRKVEAGASR
AITQFFFDIEKFLRYRDRCAAIGIDVDIIPGILPVTNFQQLQKFAGLTNVAIPDWMNKAY
QGLESDPTTRNLVGANIAMEMVKVLSQEGVDQFHFYTLNRSELSYAICHLLGARPVL
>A0A3Q8RRU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum singaporense|TrEMBL
MKVIEHLEKANGASLFSFEILPPLKGDTIESIFKNIDPLMEFNPPFIDVTYHREEYVYKE
LGDGLLKKQVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPEKDGHAYASELVTQIENLNKGRYLDDDLQNSSKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKNGANYVITQMFFDNQKYFEFVEKCREEGITVPIIPGLK
PISTKKQLNLIPHRFKVDLPDALVKEVVNCKSNAEVRQVGVEWCIAQSKELQQKGVPILH
YYSMGRSTNIQKIAEAVF
>A0A250F1Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sputigena|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYQNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
IMALRGDAMKEQRYFQPTEGGHTYATELVTQIINLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVEACKNNADVKQVGIEWAIQQSKELKAAGAPVLHY
YSMGKSDNIVKVISEVF
>A0A0K1FEK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arsenicicoccus sp. oral taxon 190|TrEMBL
MVSGSSFLAPRDHLSGASIPDMLAKEGTSFSFEFFPPRSDEAEAVLWEAIRHLEKKRPSF
VSVTYGAGGTTRDRTVRVTQRIAEETTLLPMAHLTCVGSSVGELRSVIGAYADAGIRNVM
VLRGDPAGGLGSPWVAHPEGLDHADQLVDLVRSLGDFTIGVAAFPDGHPESSSREQDADV
LVAKQRAGADFAVTQMVFDVDNYLRLRDLVVARGGTLPIIPGLMPVTNLRQISRMAELSG
AALPTSVTSRLEAVGEDADAVREVGVQIATEHAQRLMDEGAPGLHFYTMNRSTATLEVFA
NLGQ
>J4UUR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beauveria bassiana (strain ARSEF 2860)|TrEMBL
MHIKDLLAETKRSGKPSFSFEYFPPKTAQGVQNLYDRVDRMYNFGPQFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGMEKVNDALRKAYKAGCTNILALRGDPPRAQEK
WTATEDGFQYACDLVRHIRATYGDHFDIGVAGYPEGCDDNDNEDELIEHLKYKVDLGGTF
IVTQMFYDVENFIRWVGKVRAAGITVPILPGIMPIATYASFLRRCKHTGCKIPQSWLDLL
EPVKNDDVAVREVGKKLVVDMCRKLMAADIHHMHFYTMNLAQATRMVLEELNWTPSAERP
LQQALPWKPSKGFGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRLKWGEPKSLRDIANTFVRYLNQEIDSLPWSEAPLTSEADSIKSALIE
LNQRGFLTINSQPAVDGVKSSHPVHGWGPANGYVYQKGYIELLVSPKIVDQVIQLVNTNP
SLTYYAVTKNGNLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFDAKSPSRVLVESVMENWYLLNIVNNDFHDNTTIFELFRDLKVDGLDTPIAVEAEAP
VAAEAEKPAATQAEAVA
>B8GP49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioalkalivibrio sulfidiphilus (strain HL-EbGR7)|TrEMBL
MKSQKAYEKVFSFEFFPPKTDEGAEKLRKAREALAELKPKFFSVTYGAGGSTQARTLDTV
LEIQRDARFEAAPHLSCIGSTREHIREILELYRNNGIRHIVALRGDMPSGMRGEPGELRY
ANELVEFIRQETGDHFFIEVAAYPEMHPQAPSYEKDLENFKRKVDAGADSAITQYFYNAD
AYYHFVDSCEKMGVTLPIVPGIMPITNYTQLARFSDACGADIPRWIRKRLEGFGDDSAAI
RAFGEDVVTRLCEKLLEAGAPGLHFYTMNQAGPTLAIWNNLGLGGR
>S8EHU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Genlisea aurea|TrEMBL
MKVIEKIREATSGNGDRVVFSFEFFPPKTEDGVDNLFERMDRMVAFNPTFCDITWGAGGS
TADLTLEIANRMQNIVCVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQ
DKFVKVEGGFSCALDLVEHIRSKYGDYFGITVAGYPEGHPDVILDGVAPLEAYENELAYL
KRKVDAGAEVIVTQLFYDTDIFLKFVDDCRQLGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPTEITAALEPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKSALAILTN
LGLIEESKISKSLPWRRPTNVFRVKEDFMRPRARDKKLHDEWAIPLEKVEDIHELFKKFC
LGKLRSSPWSELDGLQPETKIINEQLGSINSKGFLTINSQPAVNGLPSDSPGVGWGEPNG
YVYQKAYLEFFCSPDKLNALVEKSKHYPLLSYIAIDDQGSLISNVERSNVNAVTWGVFPS
KEIIQPTIVDPASFVVWKDEAFEIWSKGWAKLYPDNDPSRKILEEVRKNYYLVSLVDNDY
INGDLFAVFKDL
>A0A379Y9W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia marcescens|TrEMBL
MNGQINVSFEFFPPRTSEMEETLWQSIDRLSILKPKFVSVTYGANSGERDRTHSIIKGIK
ERTGLEAAPHLTCIDASPAQLRDIATDYWNSGIRHIVALRGDLPPGGGKPDMYATDLVAL
LKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRAITQFFFDVESYLRFRDRC
VAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFEGLDDDAETRKMVGANIAM
DMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A483A4L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured SUP05 cluster bacterium|TrEMBL
MKISFEFFPPRTEQGRQVLAQVRQELITIHPEYFSVTFGAGGTTQEATLETVLDIQKNNA
IPAAPHLSCVDSKKENIIKLLNQYKTAGINRIVALRGDIPSGVRDIGDFHYANELVEFIK
SQYNDHFHIEVAAYPEMHPQAKNIHTDLAHFANKVGAGADSAITQYFYNADAYFRFVDEM
QKLGIDIPITPGIMPITNYTQLLRFSTMCGAEIPKWILERLKLYENDLDSLSAFGTEVVS
NLCQTLKAQGVDSFHFYSMNRVQPSLKIAKHIND
>A0A417QJS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM07-9AC|TrEMBL
MKITDVLQSDKITLSMEVFPPKTTTAVEKVNEAVREIAALKPDFMSVTYGAAGGKNSKYT
IQIAQDIKDSYGVNSIAHLTCLSSTRETVENQIGLMRDAGIENILALRGDIPKEADFPLP
DQFHYAAELVREIKRLAPDMCIGGACYPEGHPEASSKAEDILHIKEKVDAGCEFLTTQMF
FDNSIFYNYLYRLREAGILVPIIAGIMPITRKNQVARSIQLSGSCVPARFKSIVDWFGDE
PAKMKQAGIAYATDQIIDLIANGVKHIHVYTMNDPEVAAGIQNNLSEIIG
>A0A7C5DTC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MGLQQKIEAKEFVILAEMEPPKGADVSRMVKNAQKVKGMVDAFVVPEMSNAVMRMSSLGG
AMILKSKGLETVMQLNCRDRNRLALQADLLAANGCGISNVMVVKGEDPGLGDHHQARGVY
DLDLPELLAVIDGLQHGRDMAGIELNGAPEFLVGSTVEAGARDKSPELILDDINRLGQAG
TRFFITPPLFDLAAIEPVWKRVNREKTTVIPTVLLLKSLGMARYIARNVNHTFIPDTLIE
RIQGAPDKVRECIEIASETIRTLKKEGFGGVQIATIGWEDKLPEILKRI
>A0A843BL37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilus sp|TrEMBL
MTIRYEANPPKILPDVNTDESIKKFVERIKIISKKCDAIHLTENVLGYQRVSPIDAGEII
KKQIPDLPITVSLRVRDKSEEEIFEFVEKCISIGFTGVLVLMGDPSQTGKADSGQIPSLT
VRKLREKNIDSKIDLYLSVSNKPNFSKLEKKCETKPKGFITQVIQNIRQVQNLSDNLKEF
SVIPIILFPSQKNEKSAKFLDLDLESYSKEFEELLKKSHEITGDVLITSPNDFTGLDEFL
SKATF
>A0A7X1NAV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia franconis|TrEMBL
MNPIELSFEFFPPKTQEGLDKLRATRVQLLPLKPKFVSVTFGAGGSTQQGTLDTVLEMGK
DSVDAAPHLSCIGSSKESLRAILNEYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFRIEVAAYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DAHKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVAKRLESFGDDRDAIRAFGLDV
VTDLCRRLVDAKVPGLHFYTLNGAAATKAICERLGI
>A0A7X1GVF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSESNLAKILKAGHFAFTGELGPPRGANVDHVREKAAPLKGMVDSVNITDNQTAMVRMSS
WAAALIAIQEGLEPNYQMVCRDRNRLAMQADILGAYAHGIRNMLCLSGDHQQFGDHPNAK
GVYDIDSIQLIGMTKRMRDEGLFLSGAKMDGAPQMFIGAAANPFAEPFEWRVHRLAKKIE
AGADFIQTQCIYNMEKMREWIRQANDMGLTEKTYILAGVTPMKSLGMARYMKSKVPGMDV
PDDVIKRLQGVDKKKQADEGIKMACEQIEEFKEMKGVAGVHLMAIEWEHRVPEIAELAGV
LPRPQV
>A0A8J7PGE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rudaea sp|TrEMBL
MTQISFEFFPPKTDEQRATLEAALPRLKALKPEYVSCTFGAGGSTLNYTPETVRHLREDH
DLDAAPHLSCVGGTRAEIGKLIETYKAMGCKRIVALRGDLPSGMASYGEFHYASDLVEYI
RSEHNGFFHIEVAAYPEMHPQSGDAHSDLANFKRKVEAGANGAITQYFFNPDAYFRFVDD
ARRAGIAVPITPGIMPITQYSQLKRFSDMCGAEIPRWIAKRLEAYRDDADSIREFGADVV
AQLCEKLIAGGVPGIHFYTLNRAKATLAVCTRIGIV
>A0A6L7EK78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella sp. Lac1|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAEDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A5CVX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA)|TrEMBL
MKISFEFFPPKTEQGKEKLIQVRQSLSVVSPKYFSTTSGAGGTTQDTTLETVLDIQKNNN
IPATPHLSCIGLKKSNIIELLDKYKAININHIIALRGDIPSSIRNMGDFNYANELVEFIR
SKYNDNFNIEVAAYPEMHPQAKNIKSDLTHFVNKVKAGANGAITQYFYNADAYFRFQDDV
QKLGINIPITPGIMPITNYTKLLNFSNMCGAQIPKWILERLKFYENDLESLNDFGFDVVA
NLCQTLKNQGVNSFHFYSMNLVEPSLKLAKNII
>A0A6I1EE88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amylibacter sp. SFDW26|TrEMBL
MSVIRESFGLSFEFFPPQSLEASFKLWSAVDALAGLSPDFVSVTYGAGGSTRELTRSAVS
VIRENYGLEVAGHLTCVNASRQEVMDVAKGYAESGAKEIVALRGDAPKGVDSFSAHPEGF
VSSIELIEALKETGDFKIRVGAYPHKHPEAADDQADIEFLKRKFDAGADVAMTQFFFEAE
DFLRFRDRCEKAGITGKITPGILPIENWEKTKKFSARCGTLTPQWMDKAFQNTQTPEETR
MLSTALCTEICDDLLCEGVEDLHFYTLNDPSLTQDVCRALGRKIASPALHKVA
>A0A848YWH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKTNSVLEKIFASGQFAVTSECGPPRGAMPGIVKEKAEHLRGYVDAVNVTDNQTAMVRMS
SFAASIILREMGLHPVLQMVTRDRNRIALQSDLIGAYAHDINTVLCLSGDHPHFGDHAMA
ANVYDMDSVQLVEAVRNMREDGRLQGGAEVENLPRMFIGAAANPFADPFELRVARLAKKI
MAGVDFIQTQCIYNLDKFERWMAGIRDRGLHKKVYIMAGVTPMKSEGMAKYMKNKVPGMD
VPDEIIKRMAGVPKDKQAREGIDISIESIQRLKEIEGVNGIHLMAIEWEQKVPEIIERAG
LYPRPDIV
>A0A3M6JZE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilus sp|TrEMBL
MTIRYEANPPKILPDGDIDKSIKKFIERIKDISKKCDAIHLTENVLGFHRVSPLEVGKII
KKEIPDLPITVSLRVRDKSEEEISEFVDNCIEIGFSGILILMGDPSQTGKVDSGEIPSLT
VKKLKEKNIDSKIDLYLSVSNKPNFSKLGKKTDAGPRGFMTQVVQNVEQVQALADNLKEF
SVIPIILFPSEKNEKSAKFLDLDLELYSQEFEELLKKSHEITGDVLLTSPNDFTGLNEFL
GKTSL
>A0A831KMA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKLKQALEKKKFVVTSEVQAPVDESPEALVKRLELIRGRVDGVTVPEIEIEGVVVDTIKT
CELLKRNRFESIYQTTTRDKNRIQLQKDLVVAHETGVENLLVFTEDYRITGDSLQEIMFF
HVDVGKLESVLEHMREGYTVDGQELPFKAEFVVGSGIESGWGKDVPDLEMKEMERMAKIG
AGYFLTTPVFDLDMFEKFVKQVETFGIPVIAEVMILRTAGMASFLNRHFKSGLVPDWMIK
KLAKAVDKEKASIEIFADTVKGLKDLCQGVHIITIGGEERLRYYLDAAKLR
>A0A3A4PVZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MRVSNLYQKAGGKPVISFEFFRAKTEKAAQTLEKALDLLQATRHDYMSVTFGAGGSTREG
SYELIDKLKKDRGLNVVAYIAGVGLGPEDVTDVLDKFKSQGIETVFAIQGDTPQDDIDFN
PHPQAMAHASDLLAFIKARYDFCLGAAAYPEGHIHAESLEKDIEYARLKQDNGAEYLMAQ
YFYDNQFFYDFVDKCRAEGITIPIIPGIMPIYSVKMTEMLSAVCGTAIPDAVRDAIAKVP
ADDKEGVARYGIDLAIRQCRDLLKNGVPGLHFYTMNRGKSVHEIVTTLEKEGLV
>A0A8H8CIP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psilocybe cubensis|TrEMBL
MKITQKIEQSTKDNKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTAEMVKTCQGLIGIETCMHLTCTNMPKEKVDIALREAKQSGCRNVLALRGDPPMGKEE
WEAVDGGFVHGIDLVKHIRRDYGDYFDIAVAGFPEHMTLPKEELDKEIYYLKQKIDAGVS
FIFTQMFYDVDLFINWVKAIRAAGITIPVVPGIAPIQTWNGFQRATSLAKITIPKLFLDA
LEPVKNDDEKVREVGTRLVADMCRKILDADIGIRGLHFYTMNLEKGTKMLLEELNLVPRI
ETIKPLPWRQSLTPNRRHETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGHPITFADLSALFTKFCSSELKALPWSDQQASIETSVISKQLA
QINELGFLTINSQPAVNGARSDDKVFGWGPSNGYVYQKAYLEFFVNPTLLSLLLTQIERD
KNITYYVINKRGDLRTNNHSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELGAQ
WAKLYEHDSPSNKLIADFMETSFLVNVVHNDFHDPDAIFRPFYKAGAEYLAQKSKSTAVN
GH
>A0A3N5TXG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MLRVFQNDLADPEHFIITLELVPGRESSGRSVELVKKIAADAYSDGRISAVSITDNPGGN
PALSPDAIGYDIFKLGMDVIVHFTCRDMNRVGMESRALQLAMMGMKNILTLTGDYTGKGF
CGEGAPVFDLDSVNLISMLGMLSERMKKTGDPDPFFTGCAVSPFKYTKGECFAQYAKLCR
KSNAGARFIITQLGYDAVKFAELLEMQRRLGISLPAIGSVYLLTPNTARLMNDGRIPGAV
VSRSLMEKVIAEWKDPESGRAASVERAARLGAVLKGLGYRGIHIGGVHRDFRIAARLLDR
MTEIEKSWRDFAPGFDERSGRGDGYFLNQEGPGAFTGMESSRESCGFFDSMHYRMMRTLH
NTGFKSDAP
>A0A556CCJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MSQEVLASLLKSARYEILPTAGVVDRVHEYVVPGRVITVTASTGLTLEATLSTAEQLQAL
GFHAVPHIAARMVQGRTELEEIVDRLTQAGIDRIFVPAGDATPPAGGYAGALDLITDLAS
MAAPIQHLGVSAYPETHPLIPDDVTVQAMWDKRDYATHLVSNLCFDPGTIVTWLARVRAR
GIDLPLILGIAGKVELTKLARVASKIGVGESTRFLRKNTVTFTKMAKPGGYNPRKFLDKL
APVLDNPTMGVAGLHIYTFNQIKDTEIWRRRQLAALGHNDEVPSTS
>A0A2T5RNR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium saccharolyticum|TrEMBL
MKIKNIFDEKEVVFSLEVFPPRPDVPIENIYQTLEELKDIDPDYISVTYGAGGGVRKNRT
CELSSIIKEKYDVEALAHLTCINSDQDTLNKILARLEAKDINNILALRGDKPVDGEPLGD
YDYAYQLVEHIKKHNDFGVAAACYPEGHLETESLDQDIEYLKQKVEYGVDYLISQMFFDN
SLFYKFRNKVEKKGIEVPIEAGIMPVINKKQVGRIIELSDAYFPQKFKKILDKYEDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKVD
>A0A3N5G0S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSSSNLEKILTAGHFAFTGELGPPRGTDAEEVRKKASYLKGMVDSVNITDNQTAVVRMA
SWAASIIILQEGLEPNFQMVCRDRNRLAMQSDIIGAYAHGIRNMLCLSGDHQKFGDHPQA
KGVFDIDSMQLIGMVKKMRDEGKFLSGTEIGHPPQIFIGAAANPFADPFEWRVHRLAKKI
KAGVDFIQTQCIYNMEKFRTWVKQANDMGLTEKVYLLAGVTPMKSVGMAKYMKNNVPGMD
VPDELIKRLQGVDKKMQADEGIKFACEQIEEFKQLKGVAGVHLMAIEWEHKVPEIAERAK
MLPRPVV
>A0A1I0XXT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas marina|TrEMBL
MTDRPRCPRGADVCPPGPEHLPAVTERPTLSFELFPPRTPAAEPRLWQTVRALEAARPDF
VSVTYGASGRTRETTRALVRRLLRETSLTAIVHLTCVGTSREEVSQVVREFLDEGVRAFL
ALRGDPPADAEDWQPHPDGVDTAADLVALLRRIEAERVAVSPAQAVRATVRPLSLAVAAF
PRGNHATGGTRAQDVQSLLAKQEAGADFAITQVVHTADDFAGLVEEARSAGVRIPIIPGV
IPLTDPGRLRRLEQLTGVPAPAALVGRLDAIEDPEHRHEVGVDATAELLRGVLDAGAPGV
HVYTFNQHRGPLDALERAGLLGHAHDDAPDEAPGEAPGDTPAAGDRVPAAVG
>A0A5C6D893|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Brocadiaceae bacterium S225|TrEMBL
MSEEHNTNNNFKSGSNLEKLLKKGEFVVTSELGPPRGASRQAVEKKAELLKGYADAFNLT
DCQTAMVRLSSIASGAILLDMGMEPVVQLTCRDRNRIAMQSDILGAAALGMKNLLCLTGD
HQCFGDHPEAKGVFDLDSINQLDMFRQMRDEKKFQSGEELKTEGPKLFLGAAENPFADPF
QYRAARLAKKVKAGADFIQTQIIYNVEKFEEWMGMVRAMGLHKKVSILAGVTPIRSLGMA
KYMKKNVPGMDVPDELIKRLEGAEKKKAEGINICLEVIERVREIEGVSGVHIMAVEWEEI
VPEITERAGLLPRPTL
>A0A3A4SRC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MPSAFKKALDSGKFIVTCEAAPSKGTNLEKMKHHIELLKDKVDAMNVTDHQSSVMRYPSL
GGAILVKELGGEPILQMTCRDRNRMALQADLLFASSRGVNNVLCLTGDSVMLGDHKQAKP
VFDLDSSQLVAAVRTMEKGRDMAGNELDGGVRFCAGAIVTPEANPIEPQLIKFEKKLEAG
AEFIQTQAVYDMENFKKFMEYARQFPVKILAGIILLTSAPMARFMNKNVAGVRVPEELID
EMASAPKGGALNKGIEIAGRMVRQIKEEKICDGVHIMAIGKEEKVVDIMQAAGLL
>A0A1F8MXQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_53_26|TrEMBL
MHLSELFRNGKFVITCEVTPPKGVDIGEFLNTVDMVKDHVDAVSIGDNQRAVMRAASLVI
CHLLKEKNIEPLMELTARDRNRIALQSDLLGAAIMGIENVLLVSGYPPSVGDHAQAKPVY
DLDSVSLVAAAKALTQGHDITGHALDGIPSLCLGVAANPGLKPAEPHLERLKQKIAEGAQ
FIQTQAVYDPEVLEKFMESVSRLNVPVMVGHAMLRSASMASFMNSNLPGVSVPDKFIKEL
EGLPKHQIAETSLRISIDLLRRMKPLCQGVHFLVAGWEQYVPTIVEAVVGQKTRQASS
>A0A3A4WBB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MTVKTPSKLEKILAAGRLAVTSECGPPRGSDPETITKKAAMIKNHVDAINITDNQTSVTR
LCSMAACIRLKLMGLEPVLQMVTRDRNRIALQSDVLGAASFDIHNILCLSGDHQSFGDSP
QGQNVHDLDSMQLIQTVRRMRDEGKFLGGDDINRPPKMFVGAAANPFADPFEIRVPRLAK
KIAAGAEFIQTQCIYNLEKFERWMQLARDRGLHEKVYILAGLTPLKSAGMARYMKNRVPG
MDVPDEVVKRMSDTPKEKQAQEGINICIESIQRLKEVEGVRGFHIMAIEWEEKVPEIVER
AGLFPRPTEF
>A0A1Q3M5D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium 45-6|TrEMBL
MIKTTVTELIKGDKTAFSFEILPPLKGNSIEKVYKIIDKLREFDPKYINITTHQSENIYK
EFPDGAIRKVNVRKRPGSVAIAAAIQNKYGITAIPHMICKGFSREETEYAMIDLNFLGIY
NLLLLRGDAHKEGPKFEGTFNSYATDLQKQVADFNQGISADGSTFEKFETPFSYGMACYP
EKHEEAPNLESDIFYAKMKQDQGAEYLVTQMFFDNEKYFSFVEKCRQTGITIPIIPGVKP
IVTRDQLTVLPRIFRSEIPVELATDLLKCKTDDEAKAVGVEWGIQQCRDLVKRGVPSLHF
YSLMASESVKRIAKEIY
>A0A3A4ZNB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSEMSRLKRVLQKGEFAVTAECGPPKGADPEAVIRKGGLLKDKVDAVNVTDNQTAIVRMS
SMAACALLKSAGLDPVLQVVVRDRNRIALQSDILGASSLGIRNVLCLSGDHQSFGNQPQA
MGVFDLDSIQFVQTVRAMRDQCLIIGGEKLNRGPDLFIGAAANPFADPLPFRVVRLAKKI
AAGAEFIQTQCIYNLERFETWMQMVRDRGLDEKVAILGGVTPLKSARMAKYMKEKVSGMD
IPDRIIRRMEKAPSGKQREEGIRICVETIERLKEIPGIRGVHIMAIEWEEAVGEIVEKSG
LLPRPV
>A0A1B6Z7Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium EhC05|TrEMBL
MPLALSELEEAKRALDVPLFAGLSGDADVSFEFFPPKSEKMEKTLWDSVVTLEPLAPRFV
SVTYGAGGSTRERTHATVARIAKETSIPAAAHLTCVDASKEEIKEVAAAYWEAGVRHIVA
LRGDPPSEGQEFQPHPQGYASAAELVAGLKDIAPFEISVAAYPETHPEANCPQSDLDNLK
RKLDAGANRAISQFFFSAEAFFRFRDAAAAAGIDAELVPGILPVSNVAQTRKFAGMCGAE
IPAWMNELFEGLDDHPSARQLIAATVAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLL
GKRPINPAQEKAA
>A0A1I6SPG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium NLAE-zl-C104|TrEMBL
MRVSELINNTGKTAFSFELLPPLKGNSIQQVYNAIDRLKEFDPKYINITTHHSESIYKED
ENGTYRKVNVRRRPGSVAIAAAIQNKYGIRAVPHIISQGFSREETEYALIDLSFLGVTDL
LLLRGDTKKLDAEQRKMDCHQHATGLQEQVNNFNEGITFDGSSFTPPEEPFSYGMACYPE
KHEESPNMESEIYYTKMKVDNGAEYLVTQMFFDNSKYFDFVKRCREVGINVPIVPGIKPI
HLKNQLTALPRIFRSDIPEELAVALRKCKDDDEAKEVGVEWCITQCKELIRNQVPSIHFY
SLMATESVRRVAKEIY
>A0A0X8CR87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kurthia sp. 11kri321|TrEMBL
MGLLEDLKTKVLTADGAMGTLLYSYGIDFCYEELNVRKPEVIENIHKLYIEAGADVIQTN
TYTANTIKLARYGIQDEYEALNRAGVEVAKRAAKNGEYVLGTIGGIRGIRKDEHSLDEII
ESLVLQAKVLLDAGVDGLLLETFYDLEELETLVKTIRIFSDGPIVAQVSMHDPGVLLNGM
KLNDALQHLERAGADVVGVNCRLGPYHTVKALENVELPKNSFLSAYPNASLLDVEEGKVV
YESEAEYFGRAAVELRDEGVRLIGGCCGTTPEHIHEVKKHLSDVLPMENKEVITTKEEVI
REANVSKFEPLHEKVKKGRSIIVELDTPRHLETEKFLEGAAILQKAGADIVTMADNSLAS
PRVSNVAMGSILKYEKNVRALAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKVG
DFPGATSVYDVSSIELLQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVVERAIPRL
EKKIEAGADYFITQPVYSKEKIIEIYEATKHLDTPIYIGIMPLTSLRNSEFLHHEVPGIK
LSGEVLERMKAADGDKERAQAEGVQIAKELIDTAASLFNGIYLITPFMRYDMSVELIHYI
KELDEKVKGGSHVVETSH
>A0A7M4DF63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Occultella aeris|TrEMBL
MSTASLYRAPGERPTISFELYPPRTPKGEVSLQRTVLDLAQIGPDYFSVTYGASGATRQT
SRDLICSILRDTPVTPIAHLTCVGASEADLTEYVSELLDEGVRDFLALRGDPPAGQEDWQ
PHPEGLTRASQLVALLRTVVAARLGPADPVSISVAAYPGGDYGPDGQAVVDPSDVAALLE
KQDAGADFAITQVFFDPAHYAELVSAARAGGVRIPIIPGLIPLTDPKRLRRLEELTGVRV
PEQLLDSLDSAESPDEAYQRGLTASVDLIDGVLAAGAPGLHLYTFNSSKAALDLLDRAGL
APTVALGGTAPQ
>A0A7X0ZGW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria farberi|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYNNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEIFRREGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVESGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDAAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKDALRKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYIQNKQQVQIVSK
>A0A7W1CTL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
PLLHMSCRDRNVLGLQSELLGMAALGMRHVLPLTGDPARVGDHPGAASVYDVNSVQLIGI
IKRMNEGFNYAGKSLKAGTQFVIGCTFNPNSKNLDAQVSRLERKITSGAQYVMTQPVFDV
RVLDEMVRRTQAFGVPIFTGVWPLLSGRQAEFLHNEVPGIVVPDEVRARMAGTEGEEGGA
RGLEIAREISQATLERFPGVYLITPFLRYSATVELAAFARGL
>A0A3Q9RKG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peribacillus asahii|TrEMBL
MEFRKELKQRILIGEGAMGTLLYSRGIDHCYEELNCTEPDQIEAIHRTYLDAGADILQSN
TYGANFHKLKRYGLEDQVSQINRQGIAIAKKVAQGNAFVFGTIGASRSIRKSDLSLEEIK
RSFREQLYSLLLESPDGLLFETYYDLEELETVLQIARQETNIPIITNVTLHELGNLQNGV
QLNEAFKRLEQLGSDVVGLNCRLGPHHMIRALESVQLPSNAVLAAYPNASLPDYVDGRLV
YDAAPEYFGSSALQLRDQGASIIGGCCGTTPQHITAMKAAVCDLAPIVEKKMQVTKVETI
EVREQDRTPALYEKAKTERTILVELDPPKKLGIEEFMKGSRALKEAGVDTITLADNSLAS
PRISNAALGMLIKSQLDLNPLVHITCRDRNLIGLQSHLMGLQTLGLNEVLVITGDPSKIG
DFPGATSVYDLSSFDLISLVKQFNEGLSYSGQSLGQKTNFKIAAAFNPNVKYLDRAVQRM
EKKIECGAHSFLTQPIYSTSQIEEVYEATKHLETPIFVGIMPLTSTRNAEFIHNEVPGIK
LPDHVRRAMAAAGNDPIQAQKEGVAIARELVDAAMDKFKGIYLITPFLRYEMTAELTRYI
RTLDQTKTSEVAAYE
>X6G5R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L2C085B000|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A4R4AGW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marichromatium gracile|TrEMBL
MSPQDPTPTYSLELFPPKTAERMERLKSEITTLNTVSPRYFSVTYGAGGSTRKGTFETVS
WLRSQGIDTAPHLACIGSPRAEVEELLEHYREQGIDRLVALRGDLPSGMGGGLGGDFRYA
NELVEFIRERTGDHFRIEVAAYPEYHPQSGTPDRDLANFKRKVEAGADAAITQYFYNADA
YFAFIERCQAEGIDIPIVPGIMPITNHSQLARFSDACGAEIPRWIRRRLEGFGDDLASTR
EFGHEVVLQLCRRLIEGGAPGLHFYTMNQSGPTLRLWQELGLPTGD
>B4U6B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenobaculum sp. (strain Y04AAS1)|TrEMBL
MKIIELLKNKKGVSFEFFPPKSQKDKEALLETAKELKVFEPNFVSVTHGASGNSISQKPP
IEYTKETVLELKNSLGLNIMAHLTCISHTKDELISILGFYKENSIDNILALRGDIPKNGE
KRGCSHASELIDLIKTYFDESFCIGVAAYPEGHPESPNMEWEIKYFKQKVEKGASFAITQ
MFFDNSYYYEFLDLCHKANINIPIIPGIMPITNIKQISKFASMCGATIPSYITDALENLN
EEDVVKKGVEIAINQCEDLIKNGIKHIHFYTLNKSKATLQILKAIKL
>A0A1F3Y677|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionales bacterium RIFOXYD1_FULL_53_11|TrEMBL
MRMTVEAKDMVFKADVNLVDILTEGRFALSAEIIPPRNGAEYVKILGDIGALVRGGAEFL
SVTKGAGGSLRGGSLPIAQAVKEKFGKTAVAHFTCRDLLAVEIENQLVDHHYFGIRNILA
LRGDPPEGQGGWCAREGGLDFAHQLITQIANMNKGVYLVRPNAPAADAPVRRDATDFCIG
AAAYPEYPDADDRVRFFKMKVDAGAHFGMTDMLFDPEAYARFMDACAAAGIRIPVLPGTR
LLRSKIHMERMLARFKVGVPHWLRAMLPDDDSDVSGAVSRGAEAFLKLVEKLRGYGAPGI
HLFVIGDVSGSEYVLSELAWGRKKDKYSLADVREES
>A0A5K7ZAJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina widdelii|TrEMBL
MNMNTESFVVTIEVVPPDGPDATSVLDALRPLAKLPFYGFSVATNPVAKPRMSAMALCAL
IRQRTGKPAILHLTTRDHNRLGLQGELWGARALGIDTVLAATGDFVALKDRHYTSTVRDA
DVYELVGMARKAGMHTGVVFDRHPETNGLERAVAHLKRKVEAGAQFAVTQPVYDEAGADE
ITTVTRDLGIPVVMGILPLRTPRHAEFLHTKVAGIAVPEALRKRLHEAADPIAEGVANAR
EIFALARSRFAGACIMPPFDHYEIMPEILQI
>A0A3N0EF40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsaceae bacterium YIM 96095|TrEMBL
MFGSPSHTETAHDAAQRPRHISDLLKTGEPTFSFEFFPPKTAEGQQKLWQVIRELEALSP
SFVSVTYGAGGGTRDHTVEITERLATDTTLLPVAHTTAVNHSVAELRHLIGRFADAGVSN
MLALRGDPPGDPLGEWVKHPEGLEYASELVELIKQSGDFSVGVAAFPFKHPRSASVEEDV
DFLIHKFDSGADFAITQMFFDAEDYLRLRDRVAARGRDVPIIPELMPVVKYSTIEMSEKL
SGAPFPAHLAEEFEKVKDDPKAVRELGMDQAQRLCERLLDEGAPGIHFITFNQATATREL
YERVAGYRVPAMAGARP
>A0A2U1D0K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tamilnaduibacter salinus|TrEMBL
MKLVHEQAQGTDQGLILQDLAREASIEATPSQILDTHDVAGLLPGGTSVYVPFLPGADFQ
RTVDACRKLIGDGMHPVPHVPARAVESHDQLRDWLAGLTETGTHRIMLIAGDNDAPAGPF
DDTLGVLESGLLADHRIHQVGIAGHPDGHPVAGSDLITSAMARKRDYAIETGTHMWVVTQ
FAFDSDTFFEWLEQHCEVMTPMPVYFGLAGPTKLTTLIAYAARCGVGVSARMMKRRPSAA
RLLTSWTPDGLMQSIAQHVIDEPHSLLAGIHVFPFGGLERSAQWLHGLCSEANELNQQPS
QAGV
>A0A7X7IS65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pirellulaceae bacterium|TrEMBL
MNRSGIEAAAWRYASEGFENLLAITGDYPTGGFGGTAEPVFDLDSLGLIHLLRLMNEGLR
VPGRRGSLETLPATNFFIGCVVSPFKRHERELMPQYFKLIRKIAAGAEWIIPQLGYDMRK
FHEIKLLLASRRLDVPVVGNVYVLSGFVAKLFHSGKLAGCVVSDELLETCQKQAASPDKG
QKFFHEFAAKQLAVFKGLGFTAGYLGGMAKAETFGKVIDLAESFGENDWRDFLPEICYSQ
PGEFFLFEHDAKTGMSAPDRINPDYLRSLQRRPRSKHVTLNYRVSRMVHSLAFHRGHKLY
GLMTRLFRRLEKEGKPNFLGRMSYWFEKRAKYVGYGCEDCGDCSLPDCAYLCPNSACSKS
TRNGPCGGSLDGRCELDDKDCLWARAYERLKHYGESEQLTEGLPIIHDAGLKHTSAWANT
YLDRDHFATLAKQQAEDNAKNNNKKADG
>A0A6J4BTB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. HMP9|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGISFEFFPPKTEKMDTQLWEAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEASKAEIDQVAEEYWTAGVRHIV
ALRGDMPTLGQPYHAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDFDIDNL
KRKLDAGASRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPAATVAAA
>A0A2T4Z3S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desmospora activa DSM 45169|TrEMBL
MRPDLKEALSHRLWVGDGAMSTYLYQQGIPVGVCPEELTLTQPEWIIDVHRRYREAGAAL
IQTNTYGANRDRLARYGIESKTTRINREAAALARRGAGDEAYVLGSIGSILAGRVLHYSE
ADYRDMYEEQATALLYAGVDGLILETFIDLKELVLALETIRPLTDVPVLCNLAMVEVGRT
RDGHLLSDAFQVLQQKGADAVGLNCRLGPLEIERALKQTQVPEGIALAAYPNAGRLGLYD
GEYQYKSTPQYFGERALSLREQGVQIIGGCCGTTPEHIKAINAAIAGLAPLPRINPAPST
QTGTQERIHIQPRTRPSVVDQVKEETTVIIEYDSPKDLDISQYLRGAEELTHAGADAITL
ADNSMATTRMSNMALGAIMKERTGAEPLVHITCRDRNLIGQQSHLMGLHALGIDQILVVT
GDPTRIGDLPGSSSIYDVTSFDLIRMVKQLNEGISFSGRPLKQKARFVVGTAFNPNVAKI
EAAVRRLHKKVEAGADFVMTQPVYDVESLHRVKEATKDIPIPIFIGIMPLTGHRNALFLH
HELPGVKIPDPVMQRMEGKSGAEGREEGVAIAQALLDEAVKLFQGIYLITPFHYWEMTAA
LTRYIRLRTQQNVVSGS
>A0A7Y8CQ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cedecea sp. P7760|TrEMBL
MSFFHANQREALNQSLAEVAGHINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPQFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNSGIRHIVALRGD
LPPDSGKPDMYASDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLRRKIEAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFRQAKKFADMTNVRIPSWMAQMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A2E0XRU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MKIWQKPSFRFLLQETHTFVTCVELVNTRGIITEREGTRLLKLARELSQNPRIHALCITD
NAGGNAMHSGDTLGTDLISRGQEVVIHLSCKDWNRNGLQSKVWKLASEGFNNVLALSGDY
PISGYQGQASAVFDIDSVGLLKMMSEMNAGLRISVGQKKKDQVLKNTSFFLGAVVNNHKR
YEREVMPQYFKLKKKIENGASFITSQIGYDARKQDELLKYMDCFDCHVPVLSNVYVLSLT
AARFFHANNIPGVTVTDDLLALVEKQAGSSDKGKNFFLEFAAKQCAIAKGLGFRGVYLGG
HLKSSDYERILEIADQFGENDWKDFSKEICFHQTDEFYFFEPDTSTQLSSTEINREYLHS
KSLKALQVSKQNIPLSYKINRVVHDKAFEKGTLGFGLGKKTSQAIERTNKGVQKILHGLE
QTFKMAAFGCQDCGDCSLPDIAFLCPESQCAKNQRNGPCGGTDQGKCEVGEKECIWSLAY
DRLKAYGQEEQMLNGPAIFKDGSLKGTSAWINTFLGRDHHGGGGK
>A0A117SUS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrobaculum sp. OCT_11|TrEMBL
MEIIAEVTPVRDRTKLLKKLEALKPLVNRIDIPEAPGGKPTAHALAVGALAKQMGFEPIV
HIRLLDVNKTGLKSLLGGAYLLDIKDVVVLQGDPPAEGRPVGEVSTEEAVEEAKKMGLRA
GALLSLRRDHRKRVETLRADFYLALHLTDAKQLEGLPPIVYPYVMVRTSNNSELIDRLRQ
TAVEPHEALALVEALEGTAPGAVISVPGDFDALVGLLKQIKTRRG
>A1TUG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax citrulli (strain AAC00-1)|TrEMBL
MSLSTHEAALPVSFEFFPPKTPEGADKLRTVRQQLYAHRPEFCSVTYGAGGSTQEGTFGT
VREILSEGVQAASHFSCIGATREGVRTQLAQLKAMGVSRLVALRGDLPSGYGAGGEFQYA
SDLVAFIRAEAGDDFHIEVAAYPEVHPQARSPEADLQAFATKVRAGAHSAITQYFFNPDA
YWRFVDDVRALGLDVPVIPGIMPIMGSTQLMRFSDACGAEIPRWIRLRLLGFGDDSASIR
AFGLDVVTALCERLRAGGAPSLHFYTMNQSAATLEICRRLGL
>A0A1F8MQU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_52_12|TrEMBL
MASRFKEALNSGKFVITSEVAPPKGTNLEKMFHHIDLLKDIVDAVNVTDHQSSVMRYPSL
GGCLAVKERGGEAIMQMTCRDRNRMALEADLLFAYSRGIGNILCLTGDAVPVGDHKDAKG
VFDLDSLQLLKAIRQMASGEDLGGNKLDGAVEFCAGAIVTPEARPIEPQLIKFEKKVEAG
AEFFQTQAIYDLENFADFMVHARKLKAKVLAGIVLLSSARMAKYMTENVPGIFVPPDFID
ELSKVPKEQMLAKGIEIAGRTIAALKKEALCDGVHIMAIGKEEVVPDILAAAGL
>A0A2N0KNK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Casp-Chloro-G2|TrEMBL
MKIKEILAKTRPVSFEFFPPRSADGIPDVLEAISELAIYSPDFVSVTYGAGGSTQAFTEE
ITLQAKNDLGVEVMAHLTCVGQNQEELDRVLARLEAAGVENIIALRGDPPRGSTEFVAVE
GGFRHASDLLKHVKSNYEFGVAAACYPEGHTESVDLTADLEYVKKKVDLGADFLVTQLFY
DNQYYFDFVDRARAAGIQVPIVPGVLPVLNSAQVRRFTSLSGSNIPPQLDVLLDKYADNE
NSARDMGVEYATEQVRGLWDAGVPGVHFYVLNRSYSVSRILDNLQIPGHTRPN
>A0A246TY44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. R693|TrEMBL
MALNSDARRKIGISFEFFPPKSEEMEGQLWNTVSELQDWNPDFVSVTYGAGGTTKAPTLA
TVSRFIAETPLATASHLTCVGATKDETHGVIETFRKVGVKHFVALRGDAPGGVGAPYQPH
PGGYANAAALVAGLREIGDFEISVSAYPEKHPESRDTAADIDMLKQKADNGATRALTQFF
FDNDNFERYLEKVRAAGVNIPIVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFDDK
PEERAKVAAEVAAEQIEDLARRGLTDFHLYTMNRAPLVSAVLTNLGFTREGAKKAGAAA
>A0A270AZ15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella osloensis|TrEMBL
MTTPFSFEFFPTKTDDGQTKLLATFNELNALKPQYFSVTYGAGGSTRERTLGIVKALSEK
SDTPITPHLSCIGDDKAKIGELLDYYKSLGINRLVALRGDLPSGMVGLGELPFAVDLVKY
IREHSGDYFRIKVAAYPEMHPQAKSFDADIQNLLNKYHAGATEAITQFFYNADSYLYLRD
ALAKKGVTQDEFPIIAGIMPITNASNLIRFADGCGADIPRFIRKQLADYGDDKKAIRQFG
FEVMVNLCERLIAEGVPSMHFYSMNQVNPNKQLIEALGLV
>A0A2T3B0U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amorphotheca resinae ATCC 22711|TrEMBL
MEKITDKIAALPPDSTFFSLEFFPPKTAMGSSNLRARLDRMSRALRPLFITVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNISKELVDRALEDARSLGVRNILALRGDPPRTEE
YTVNGDAEAKKDDLEFEWAIDLVRYIRKQYGDYFCIGVAAYPEGHADESHPQGQSLEHDL
PYLVDKVQAGADFIVTQLFFDVDAYDKFEKRLREHESGAFKTIPIIPGMMPIQSYQMIKR
TTKLSHAALPSDIMSRLDEVKGNDEMVKKVGVDIVSEMVEHLKKSPTNTSKQPRGFHFYT
LNLEKAVAFILERTNLIPPLPSETDSAVLEPLPTTLQLQNLSINGASENESSSRRLSSAG
SDPHNRVIITASHASNPDFETTALEASVPAEPINSRSNTLAISEGEGALGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSFNQAIKLWSYPSSVQDITNLFLQHLEGKLSAIPWSE
EGFNEETSTIKDQLLKLNRKGWWTVASQPAVNGVPSTDQIFGWGPKNGFVFQKAFVELFL
PSKDWNELHAKLTSPAIAGQVGWYASNAKGDFISSDTSDGVDGMNGGSTHAVTWGAFPGK
EIITPTIIEKVSFQAWAEEAFGIWAEWARVYSNRGGRGGGEDAEQARKSKELIEEVMSDV
WLVNVIHHSYVDKEALWDLLLS
>A0A372J444|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus sp. LHW52908|TrEMBL
MPTEVRDGTRAPTRAGLPTPADGPPTGHGARTALERALRAASYEVLPLRGAEESVVEHVP
RAVPLTVTVTEAKGLVPTLELAERLTGHGFTATPHLAARLVRDAAHLAEVVARLRAAGVS
GVFVVGGDAAEPAGTFPDALSLLEALDTTGSRFETVGIGGYPEGHGHIDPELIDRALEQK
APHATHVTTQLCFSAATTVAWAREVSRRGVDLPIRVGLPGAVTRQRLVRISARLGLGRSA
RFLAKQQGVLGRFFLPHGYRPDRLVDGLAPTLGRPEHRVQGFHFFTFNEVARTEAWRQEW
LARLSDAGTG
>A0A5I8I0P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Ouakam|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2T4UHK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Conexibacter sp. Seoho-28|TrEMBL
MRIDELLARNGDPTFSFEFFPPKTEAGEENLYAALRELQPLEPAYVSVTYGAGGSTREKT
IEIVSTIKEKFGLEAMAHFTCVNATTDDLRGALDQLRDAGVENVLALRGDPPAGETRWTK
TDGGLEYSRELVELLAAEYPEFAIAGAAFPETHIDAVSPEADLEYLKQKVDAGATFLVTQ
LFFENRFYFDFVERARAAGITVPIIAGIMPITNVEGIKRMTTLSGCALPAGLEQALDARR
ENPEAVAELGVSYATLQCADLLAGGCPGIHFYTLNRSPATRAILSALKLWRPWERATGLA
VPPEKATA
>A0A1G3JXZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium GWF1_63_6|TrEMBL
MTLNDPVAPLYADLAGDCHVSFEFFPPKSEKMEAQLWSAIETLTPLAPKFVSVTYGAGGS
TRERTHNTVARIARETPLAAAAHLTCVGASKAEIGEIADAYWDAGVRHIVALRGDPPEVG
GSFEPHPDGYKGAAELVEGLAQRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGAIR
AITQFFFTPDAYFRFLDKTLAAGITADIVPGIMPVSNFAATQRMAAMCNTQVPNWMARLF
EGLDDHPASRQLVSATIAAELCQKLYTGGVRDFHFYTLNRSELSFAICHLLGLRAKPAAN
A
>A0A7X0KU00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium thalassium|TrEMBL
MTSTAHVPHTAAAIELVEGFSLEMTGKDVPGLQEAAHAIPAGTKINVTFLGNEDLDMRVA
ASKAVKDLGFTPVPHISARRIGSQAQLEEFLGRLQEVGATEHVFAVGGDPAEPEGPYPDS
LSVIQTGILQQYGVKEVSIAGYPEGHPDIETDVLWRHLDDKVASLKEQNLDCTILTQFAF
DTDPVMSWIDAVRARDIDATIRIGTPGPAGIKRLINFARRFGVGANAMIVKKYGFSLTNL
MGTAGPDRFVSDLAALLEADEASGSVKLHMYTFGGLLATADWARAFTTGE
>A0A7K3LZ79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytoactinopolyspora mesophila|TrEMBL
MSQGLPTTTQGNGPTIRELLAAGGRSYSFEFFAPKSPEAEELFWRTMRELERLQPTFISV
TYGAGGTSREQTVQVTGQVAMDTTLTAMGHLTAVNHSVAELRHVIGQYADVGIRNILALR
GDPPGDPQADWKPHPEGLNYSEELVRLVKSVGDFCVGVAAFPEKHPRSPDLDTDVRYLVG
KFDAGADFAITQMFFNVEDYLRLRDRVTAAGSDKPIIPGIMPVTNVKQIEKFAQLCGAAF
PSKLAERLHAVADDREAVRAIGVEVATEMCERLMEEGAPGLHFITLNRSTATREIYEHLG
LGAALTPA
>B7L3N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum extorquens (strain CM4 / NCIMB 13688)|TrEMBL
MWFRNARKKLSPTHDSATDSTDALRSSVSLLARDLSLEVSPREALRGAEGLETLAPGTRV
FITRLPKGSFEETLAASTRLRELGLRPVPHITARTTSDAATFAKQLGRYVGEAGVREILL
VAGSNEKAEGAFSNTLQILESGVIESSGLTALNVAGHPEGHPQADERELHRALEVKNAFS
TRTGIPLTIVTQFFFDPAPIIAWEARIREKGNRLPIDIGLHGVTGVASLAKHAVACGVGA
SIKVLGSHSGSVLQFAQIRTPDRLLSGLAAAKARDPANLFRNIHVFPLGGFKRTVEWANA
VRNGRYSFASDGQLEVATSD
>A0A2B1YKH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKILDLLSKGIIIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADIIQTN
TYGANEAKLRTYGLENQVVQINRAAVKLAKAAITDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALIEENVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQLALHEAGTTQNGN
DVNEILEQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPAHIEAMKRAIANVTPVTEKQIVQRQQVVP
MQTKRISTHVTLAEKAKKQTTVIVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNEGRSILGKSIGSATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIGEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMDGHDTQESAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITENLVNYVK
EKQEVKEGVN
>A0A221C259|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGTATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1Q9JT66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerostipes sp. 494a|TrEMBL
MKISEILKKKATISFEVFPPKNKEGDISSIYYTIEELSKLSPDFISVTYGAGGSTKGKTV
DIASAIKKEYGIESVAHLSCITSTKEDVLKECNRLKEENIDNILALRGDYPAESTDFDPK
KLEFHYASELNEFIHENFPGQFCLSGACYPETHQEADGFKRDLEALKKKVDAGAEYLITQ
IFFDNDYYYRLVREARKIGINVPILAGIMPITNAKSLIRTTKMCGCTIPYQLSTMIEAYY
DNPAAMQEIGINYAAQQIIDLITNGVDGIHIYTMNKPEIANRIFDSIPTVLKELNHD
>A0A2U8P2C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium ottawaense|TrEMBL
MTDLTIPARADGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPAG
GIGTPYASHPDGYQSSAELVAGIKKRHADIEVSVSAYPEKHPEARDFDDDIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRVRGINIPIVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A523YXJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MKVIDLWKSDQKTTISFELFPAKSDKGAETLEKTIDQLAALNPDFVSVTFGAGGSTREGS
RQLLQKLKHEKGLDILAYFACFGLGPEEIGSVLDSYQAIGVESVLAVRGDAPRDESFEPH
PDSLPYASDLVAFIRQRYAFCLGVAAYPEGHIDAPDRKKDLEYLKLKVDQGGEYIITNYF
YDTRYFFDFVDRCRGIGIEVPIVPGIMPIYSIKMMEMLAGMCGATITEEVHEGLASLEEG
DKDALIAFGIEFAYRQCAELLQAGVPGLHIYTMDRSVSTVGLVNRLRAEGLL
>A0A2G9YBF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium (Candidatus Ratteibacteria) CG23_combo_of_CG06-09_8_20_14_all_48_7|TrEMBL
EAGLEPILQMTCRDRNRLSLQSELLSAAAFGIENVLALTGDHPKLG
>A0A2S5J647|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter hyointestinalis subsp. hyointestinalis|TrEMBL
MLKDKIKENKPGILLYGITPPKINLSKDEAYQIAKKQLERLENTGIDGLVIYDLQDESSR
NNKKRTFEFCGTIKPEIYHKEFLKLSYPAVIYKAVGNYTKEEFANFLNTSNNDMLSVFVG
ASSKNDLLKFNLNEAYKLKKEQGGNVTVGGICIPERHEKKGDEDLRVASKIIKGCEFFIT
QAVYNIENAKRFLDDYANLGIKKVPIIFTFTPCGSPKTLEFMRWLGISVSKQFEDRLFES
DDPLSASVGLSLDMFEFLYKYGRAKGVSVGANVESISTRKVEIEASINLLRGIKNIIQNE
KECNLEELIQSASKFYE
>A0A7V2P7E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MHLSELAKSGEFIITCELASPKGVNVQDFLDQADQLKSYIHAISIGDNPRATMRAGSWAM
CHLLKSRDIEPIMELATRDRNRIALQSDMLGAAILGIENIILSDGHDPSVGDHTEATRVQ
DLNCISLAGAAKTLAGGHDMTGHALDGTPSLCLGITANPGLEPLEKQLDTIKEAVAQGAQ
FIQTQPVYDPAVLERFVDSIYNLDVTIIVGHMMLKSVSMASFINSNLEGVTVPDAMMKQL
EGQPRNIAVETSLQMSTNLIKTIRPLCHGIHFIPASWERYVPRIIEALTDR
>A0A7V2QKJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MVFRDVLNSGKFVVTSEVAPPKGTNLDNLRHHIDLLKDKVDAINVTDHQSSVMRFPSIGG
CLAIKEQGGEPILQMTCRDRNRLALQAELLLAYSRGIRNVLCLTGDAVPVGDHKEAKGVF
DLDSVQLLKTIRLLETGKDLGGNDLDGAVEFCAGAIVTPEANPIEPQLIKFEKKVEAGAE
FFQTQGIYDLDNFGRFMEYARQFPVKVLAGIILLSSARMAKFMTENVPGIFVPQNLIDEL
AAAPKGEALSRGIEIAGRMIATLKKDAICDGVHIMAIGREEVVPDILAAAGM
>A0A523U7M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSNLSEALKSGKFVVTAEIGPPKGVDIEEMLGDAELFRGRVDAINVTDQQSSVMRLGSLA
TCHLLKERGLEPVFQMTCRDRNRIALESDLLCAHVLGIENVLCLTGDYVSLGDHPEAKPV
FDLDSVSLLETATLLQQGADLAGKELKGRPNFFLGAVVTPGADPLEPQIIKMEKKVRAGA
QFFQTQAVYEPEEFERFVKEIKHLGVPVLVGIVLLKSAGMARFMNKNVAGVHVPDSFIEE
IDRAENKREKSIEIAARLIKEMKDLCQGVHIMAIGWEKMVPRVLDAAGL
>A0A7V2KSA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MIRKISDILAEKEMTYSFEFFPPKTEKGVEKLFEVAGEYKELNPDWFTVTYGAGGSTREL
TMELVDQFQKRFGVPTMHHFTCVGHSKDELANIIEEMKRRNICNILALRGDPPAGVENWE
PAPNGLEYSYQLVELIREHNGFFSVGVAGFPEGHIDCPDKETDTKHLKMKIDAGSDFVIT
QLFFDNKDYFDYVNRLKAASIGVKVLPGILPITDYKKLIRFCAGCGATIPKRVHDIFRPI
DGDEEATYKAGIDFVIEQCNELLDGGAPGLHFYTLNKLDPVREVLGKIRR
>A0A6H0KP47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CBA7301|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A6V6YTS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium chungangense|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCHYLGINN
VMALRGDAMKHEQSFVPKDGGNHYAVDLVRQINDLNCGKYLHEVMDVDNRADFCIGVAGY
PEKHLESPSLQSDLRRLKEKVDAGADYVVTQMFFDNAKYFAFVEKAREMGITVPIIPGIK
PIAVQKHMQILPQIFRIDLPEDLIHAVDKCKNNAEIKQVGVEWAIQQSKELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A7X3QFZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSFAEAMERGEFPVSLEITPPLTSKPAVLRRRARLLEARTLTVNVIQRPERQSSLEAALE
LKREGLEPIWHLATGGRTRDAIAADVTRAHEAGLGHVLCLRGDHAADTPGTRVTEAIAIV
QERAPGMAIGAALDQYRTDERADRLLTAKLRAGARSIWTQPVFDLAPLLRSAGFVKATRP
DAHVVAMAMPLLTPESLDAISERLHIPAPEALRTRIAAGEEEAWGAFEETLATLARVELV
DAVAIMTYRADPPEGTAERIIAALRRTGIGDTAGAAADR
>A0A317HAB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MAARTYSFEFFPPQTPEGVEKLRVTRKQLAQLKPAFFSVTFGAGGSTRDRTMGTVLEIQS
EGHQAAPHVSCIASTKTAVRDMLQRYREAGIKRIVALRGDMPSGMVEAGEFRFANELVAF
VRSEFGRAFHIEVAAYPEYHPQARTAQDDLANFKRKVDAGADSAMTQYFYNADAYFAFVD
ECRANGIEIPIVPGIMPINRFSQLARFSDACGAEIPRWIRRKLEGFGDDAASIRSFGLDV
VTQLCDSLLRGGAPGLHFYTLNQAGPTTTIWQRLGLS
>A0A0K9Y3E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. Hurlbut01|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICASIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTHGGHGSAMELVHQINDLGRGKYLHNQDEICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEDLINEVENAKNNDAVKQIGIEWAIAQCRELLEFGVPVL
HFYSMGKSDNIKKVAGALF
>A0A2E1ZAX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSGQIEEQSRLERVLRSGRIAVTAELNPPDSASPDSVYENALVLASLCDAINATDAAGAN
VHLSSLAISALLAKAGYEPVMQMSCRDRNRIAIQGDLLGASALGIKNILCLTGDGVQAGD
HPDAKPVFDLESVTLLKTAKRMEEKGTFLSGRKLHTSPHFFLGAAANPFVPPFDFRPLRL
KKKIDAGAQFIQTQYCFNVARLKTYMQEVNDMGLTDKAFVLIGVGPLKSAKSAEWIRSNV
PGVVIPDGVIKRLKGAQSQANEGKKICLEIIQEVMEIKGVSGVHVMAYRQEELVAELITE
SGILDHRAKKYQKGKA
>A0A4Q6F166|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
DSSKTSVAVETCTPVPLVEKSAWSRKIALGEVVTSVELLPPASVVPTKILESSRRLKEAG
VDAVNIPDGPRASARMSAILTAVMIEQQAQIETVLHYTCRDRNLLGMQSDMLGAHAIGLR
NVLLVTGDPPKMGSYPNATGVFDIDAIGLTNMVTRLNSGIDLGSRPIGEPTALSVGVGVN
PVHADFEYEMKRFMYKVEAGAEWAITQPVFDLAALYRFMEYIDKNNIKIPIVAGIWPLMS
YRNAQFMHNEVPGVSIPDDIMKRMHDAQTAEDARKVGVDIARGMVASLGRDVQGFQVSAP
FGRVDLALEVLSGVTR
>A0A552IR96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis novacekii Mn_MB_F_20050700_S1D|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSKSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>A0A2A4UB74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MRLSNILSNAEKPLISCEFFPPKTDKGEENLWKCLXELQXIXPAYVSVTYGAGGTTQERT
KRIVLGIKEKTGLSPVAHLTCVGSTTEELGXLLDEYAQAGIENILALRGDAPEGQDSFEM
TDGGFAYATDLIDFVHSRGDFSIACATYPEGHPESKGGVADDIRYLKMKQDNGAICAVTQ
YFFDNELFFRFRDEAVKAGVTMPLIPGMMPILNYEQIVRFSXMCGASIPAFVHEKMQPIQ
TDLDAVKALGIELATKQCQALIANDVAGLHFYTLNKSEAMIAVAKEL
>A0A523S7R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAKSFREVLDSGEFIVTSEIGPPKGTNIENMRHHIDILKDKVDAINVTDHQSSVMRFPSI
GGCLEIKERGGEPILQMTCRDRNQMALQAELLLAYTRGIRNVLCLTGDAIPVGDHKEAKG
VFELDSVQLLRAIRQMESGKDLGGNDLDGAVEFCAGAIVTPEANPI
>A0A3D2JS08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MLKNSDRFLTAVEIETSRGLLMSEASRKTAELAKSLSEFDRVDFVALTDNPGGNPHIRPE
VLGQDLLFRGRDVVINMSCKDYNRNGIESRLWALGSQGFTNVLALSGDYPIGGFQGQAQP
VFDIDSVGLLELMSQMNDGLPNQMWGSAGREDRLEKTDFFAGCAVSPFKKFEGELMTQYF
KLAMKVRSGAKFAVTQIGYDSRKASELHQYVNSNNIDIPLIGSIFILTAPAGRFFNRWGV
PGVWVSDELR
>A0A523QCD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIGDIIQARGSSLSFEFFPPKDAAAEDRLFQTITTLKAYEPTFVSVTYGAGGGTLRNTR
KVILRIKEETTLTPM
>A0A210S0J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter hirudinilacicola|TrEMBL
MELSVEFFPPKTPEGEKKLHLVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AVVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
TETGDWFHIDVAAYPETHPQAKSPASDVDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YDLGLTQPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDIASIRAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLDLTK
>B1KDB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella woodyi (strain ATCC 51908 / MS32)|TrEMBL
MSFNHAQHSTSLNQSLAELNGDINVSFEFFPPASPEMEQLLWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETDLVAAPHLTLVDASDEELKELAKHYWNSGIKDIVALRGD
LPEGSPKPTRFANDLVGLLRSVADFDISVAAYPEVHPDARNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVTNFKQLKRFAGMTNVGIPGWLHKQFE
GLDDDPVTRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGR
>A0A3D1ZAW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAKIPDLANNGSSSLKIICDFSPPRGGTPSLIGDLDGLNPDIVSVAYNPGKSVRVNPVAA
AAWIKANTKQDVVFTLATRDMNKVAIQSLLLGAQLLGLQNIVIVEGDGLSNRDRKRFKAV
YDFQPTSLIESVRDMNQGKDFRGLKLRVATDFSVGATIDMGRPSDSEIPLAVRKAQTGAK
FFLAQAEFDPSVIARFRADFESHFDKGHAPPVFYGVQILAEDGIIFGNVPQGTRSELESG
RSGEEIALELIQNLMDQGVRTLYLVPPIFRGGRRDYDSARRVIESARRLAS
>A0A817XFN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood1|TrEMBL
MEFTLDDNQTVPDTHKMYDNEINLESMHNANIFKRIESEGANLGARGCSLQPVKYVSLID
KILKRIADNDRWYSLEFFPPRTASGAANLIGCFDRMAAGQPLFCDITWHPAGDPASNKET
SSMMIANTMLNYCGIDTMLHLTCHGATKAAMLEYLYKAKDFGIRNLLALRGDPPVGEDWD
PAKSDFRYAIDLVRFIRQHFGDYFIICVAGYPQGHPDSTSYEDDIAHLKEKVDCGADFII
TQLFFQPETFIKFESDCRAIGITCPIIPGILPIQGYASLRNIVRLAKLDVPKEILACIEP
IKENDEAIRNFGVQACLDLCRTLLDSGKVNGLHFYTLNREFATIEILKRLGLWLEDQPLR
ALPWKKTSYSHARSKENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGVLADYH
LFYMKIDATRDELLDEWGRELTCEQDVWQMFACYIGGEKNHQNKVVRHFPWTDEELSSET
TLIKNNLVDFNKRGILTINSQPAVNGKPSSDPIVGWGTPNGYVYQKVTIHFCNLIADNIP
ALQAVLKKFPNVNYHFLNKSGGINETNADDEQPIAVTWGVFAGREIIQPTVVDPVSFMIW
KDEAFSLWTERWGKLYEPESRSHAIIDKIANTYFLVNLVDNDYPQGSCLWQVLDSMFEYQ
KLSNQPIDS
>A0A081NXZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus tyrfis|TrEMBL
MKPDLREALRRQVLVGDGAMGTYLYQMGFPVGISYEELNLLEPDVIMDVHRRYYEAGARL
IETNTFSANREKLSKYGLEQEMEAINRAGVELARKAVGDDAYVVGAIGSIRAGKRKNVRT
AKVKEDFRDQIEVLVDTPVDGLLLESFYDLEEMLIALRLIRKVSELPVICQFATEGTDST
HDGILLTEAFRKLTAAGADVVGFNCRSGPNGLMRSLQRVAGMEGAPPFSVFPNAGIADYV
DGRYTYAATPEYFGETARKFVDLGARIVGGCCGTTPEHIAAMTQSLQNYAPDPDALRLLQ
EAGEGSETGRIVTRLQPVSSPSAPEPNLADLAKERYTVIVELDPPRDLDIEKFMQGAQAL
KNAGVDALTMADNSLAVTRMSNLALGSLVKERIGMKPLIHIACRDRNMIGTQSHMMGLHA
LGIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKSLKKNANFVIG
AAFNPNVKHLDKAVQRLERKIESGADYIMTQPVYNAELIEKVYEATKHLDVPIFIGIMPL
ASGGNAEYLHNEVPGIQLSDEVRQRMNGLKGEEGRAMGVQIAKELLDAAMHYFKGIYLMT
PFLAYEMTVQLTEYVWEKAQRLDSHLYPLSK
>A0A1Z3N263|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae complex sp. ECNIH7|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7C1U6U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium|TrEMBL
PCGGVREGGFCEIDHLMKCVWVDAWTGVKKIGEEETFTIPLRPAETNQQGRSAWAKVIEK
NKDTDELYRVKIFPPVPLEVGTHRSPSGFLEEKLQAGDFVITAELSPPDSADPAEIIRRV
AHLKDFVTAVNVPDGAGANCHMSSLASSVILHNDGVVPVMQYACRDRNRIALQGDILGAA
ALGVTNLLCVTGDSVQSGDQKGAKPVFDLDSISLLRTAKMMRDEDIFLSGRQLKKAPNLF
LGAALNPFVSPLDARVLRMERKINAGAQFFQTQFCFDVAALKKFMTEVRARELHKKCYIL
VGVGPLVSVKAARFIKSSVPGVIIPDHIIERLERAGDERQEGKRICMETLNQIRQIEGIS
GVHLMSYRKERLLAEIISESGLV
>A0A7X9ILA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR324 cluster bacterium|TrEMBL
MSFTELYKKNKRVFSFEFFPPKRPEDLPATKALIARMSALQPDFMTVTYGAGGGTRARTQ
ELVSYIVNELKCPAAAHLTCVHHTVEEVERMLDSFAADGINKIVALRGDPSNTLEGAGSL
FPGFSCARDLVRYVKSKGSFHMAVAAYPEVHPDAKSSLEDLLYLKEKVDAGAELILTQVF
FDPEIYFAFVKEAQRVGIQVPIVPGILPIGNLKQLEIFTSKCGATIPNRLQDDLRMIGND
RVAVQAFGTSYAARMCEKLLEGGAPGIHFYTLNKSMQVEEVIKVLRGALPN
>A0A062U9K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas beringensis|TrEMBL
MSPLSSTAKGEAPNVSFEFFPPKSEAMANRLWETVERLQPMAPDFVSVTYGAGGSTRERT
HDTVRRIAQETSLRPAGHLTCVGATKEEVLSVAEDYWDAGVKHIVALRGDPPAGMGEKFE
QYPGGFQDSIDLIQGIREHRPELGRCFEISVSCYPELHPESQGWDAEIAFLKAKQDAGAD
RAITQFFFEPQIYLNFLEKARAGGVIMPIVPGIMLQPNFKGLKRIAKLCGSSLPDWLHEL
YDGLDEDEETRELVTANVAADLCRQLSDEGVRNFHFYTLNRAGLALSTCRLLGLKPNSAK
AA
>A0A4R8K734|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. BL6665CI2N2|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLVTLKPKFVSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVRF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLDNFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
ATDLCGRLIDAKVPGLHFYTLNGAAATKAICERLGA
>Q3J2Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.)|TrEMBL
MALFRLRREAAAPSALAPVEALLKGYSIEVMPRTAEKIADFRDLLPRGTRVYIAHIDGTP
IEEMVATAKRLNAEGFPVMPHFPARIVKDRATLADWIARYRGEADVKQGLILAGGLRAPQ
GDFHSSMQLLETGLFDGFERLHVAGHPEGSKDIDPDGSDRMVMEALRWKQAFAERTDAKM
AIATQFCFEPDPVIAWAERLAAEGIALPIHIGIAGPAKLQTMIKFAVACGVGPSMRVLQK
RAMDVTKLLLPYEPTEFVTGIAAHKAKNHMFGIESVHFFPLGGIKTNAEWVTANGGRSGI
PANMEKVEA
>A0A1Z8QPP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED30|TrEMBL
MIPLSFEFFPPRDAAGRDKLTAGTAEKLATLNPEYFSVTYGAGGSTKAGTRQTITDLTKR
GWNAVPHLSVDGSDLQGTLELVAYYKELGIKKILCLRGDQAASDSDNSQYAEDLVRLIRQ
HFGDSFKIIVGAYPEVHPDSATSRXDLMFFKRKVDAGADVAITQYFYNVEAYAYFVQHSQ
RLGIDIPIVPGIMPITNYASLCRFSEKAGADIPRWLDRAMAQRQASNDDLNKFGVEVVTR
LCEQLIELGAPALHFYTLNRWGATTKVCANLGQNVS
>A0A246S9G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. R634|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWETVSKLQDWDPDFVSVTYGAGGTTKTPTL
STVTRFLGQTPLATASHLTCVGATKEETHQVIDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAIGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGVSIPIVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGYDD
KPEERAKVAAEVAAEQIEDLVRRGIDEFHLYTMNRAPLVSAVLDNLGFSRRPAKSAGAAA
>A0A0X3TIK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomicrospira sp. XS5|TrEMBL
MQSQQQYEQKISLEFFPPRTEKGMEKLKTVIQELTPIQPEYMSVTYGAGGTTQSRTIDTV
RYIQTETDNEAAPHLTCIGASEESVLELLDTYEAMGIKRIVALRGDLPSGMMDPGEFKYA
SDLIAFIRRERGDTFKLEVAAYPETHPQARNCNIGIKWFKHKVEQGADSAITQYFYNVDS
YLYFIDNCERSGIDLPIVPGIMPITNYENLVRFSEGCGAEVPRWLKCRLESFEDDQESLL
AFGEDVVTELSQRLLDAGAPGLHFYSMNQSKPVLNIVKQLTFKDR
>A9IGY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)|TrEMBL
MTATSTPALSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRM
LQNLGCDAAPHLSCIGATRENLRDILSAYREQGVRRLVALRGDLPSGMGGDAGELRYAAD
LVAFIRAETGDAFHIEVAAYPEMHPQAASPAADLNHFVAKVNAGADAAITQYFFNADAYF
DFVDRAQAKGVSIPIVPGIMPITNHSQLVRFSEMCGAEIPRWIRLRLAEFGDDKASIRAF
GVDVVGALCQTLLDNGAPGLHFYTLNHAEAPLAIWRELDLG
>A0A2Z5MQ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pyrrocinia|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNTAAATRTICERLAV
>A0A3D2PMC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp|TrEMBL
MIIKRIMHTLPDISATSVIPASIEASPAQVLGPASLAGLFPQGVRVYLTDTGAASQVKLV
DAAKHLRDLGYEPVPHLAARRIASRIDFEEQVKRLAGDAGVTDVLAVGGGVEKPEGPFTS
TIDMLSTGIFDRCGIRHIAIAGHPEGSPDFNDETATAALRLKRDFGERTDAAMRIVTQFG
FDSARFIAWAEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LARGHSPESIVGPIERHWRDNPQGPIRQIHVFPFGGLQASSDWLVSRGSWRTENADHAAA
TGSVAI
>F0SUR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobotulus glycolicus (strain DSM 8271 / FlGlyR)|TrEMBL
MNKIAVELVPRDERSLISELSLINSRFPLIKTINFPDLLRFDLRSWEGCRIAQRYFQDVI
PHIRAMDIKLSDELPMQGFLIEHKINQVLVVTGDLPQDMTKKIYPSTSIEVIKKFKREMP
GIKVYAAVDPYRKSVREELEYIRRKLEAGADGFFTQPFFDLRLMEIYAEILDGCEVFWGI
SPVTGEKSVNYWETKNNVVFPRGFEPTLKWNVNFAKQALALTESRKDNIYFMPIRTGLEE
YLRGIFG
>A0A2G9MG93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon CG10_big_fil_rev_8_21_14_0_10_33_12|TrEMBL
MRVTGIIKQKKWEIISVEIEPPSVDEGIEKVYEILNPLVKKGICYINITNHAEKIEKNGD
ESLSFQIERPGTIGVAGVIKEKYREKGVIPVPHIICTGLTRSDIERTLIDLNYLGIENVM
ALRGDPPKLNGNFMEFKPKENGPSYAKDLIKQIADLREGIYTGTKKKTKIDFCIGAACYP
EGYYKSQALDENINWTKAKVDAGADYLVTQLFFDNNYYLRFIEEAENAKIKVPIIPGIFP
ISLYAHLEKLPEVFGCSIPKEIIDKVEKYKYDEEDIKKVGIEWCVKQCLNLLEKGAPSLH
FFANRGAPIEEIIKGVYNPK
>C2XGR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus F65185|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A671X7L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sparus aurata|TrEMBL
MVNQVQRGDGSWQSCKSDSSGASNSGGESSKESSRCSTPVLDTDRSDRLRDKMRRRMESG
ERWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKDKISGYLGKAKHLGLKNIMALRGDPVGADWEEEEGGFNFAI
DLVKHIRSEFEDYFDICVAGYPTGHPEADSYEEDLRHLKEKVDAGADFVITQLFFRAETF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITEVIEPIKDNDAAIRN
YGIHQAVEMCRVLMDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLQMWGQELMNEESVFEVFTCYITSQPNSSGHKVMCLPWNDEPLAPETNLMKEELEKVNR
RGVLTINSQPNINGKTSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVADPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIINYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDRKKTEEL
>A0A6G7YWJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. HDW10|TrEMBL
MSNISFEFYPPKTEDQQAQLDRTVEKLKPFAPDYVSCTFGAGGSTLTYTAETIRRLRTKH
AVDAVPHISCMGGSREELRALLAEYRSLDCRKVVALRGDMPSGMGQVGELQFASDLIELI
RREHGDYFNIAVGAYPETHPQSRDAQSDLKNFKRKVDAGADVAITQYFYNADAYFRFVDD
VQRLGVTIPIVPGIMPISNFSQLRRFSEGCGAEIPRWIMQRMQGLGDDVAAVRDFGAEVV
AGLCDRLLQGGAPALHFYTLNLARPTVAVLNKMN
>A0A6M7W608|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. NZP2298|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILNETSLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A6N6SDS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Defluviimonas sp|TrEMBL
MPAPRLSFEFFPPHTLDASFRLWETVHALQPLRPEYVSVTYGAGGTTRELTHEAVTTIGR
NYGLRVAAHLTCVDATRAETLEIADAYAEAGVRDIVALRGDAPKGADRFTPHPDGFANSV
ELVEALAATGKFNIAVGAYPEPHPEAADSRADVEWLKRKIDAGASRAITQFFFEAETFLR
FRDACTKAGIDAPIVPGILPIISWEGARRFAERCNTHVPPRLEEAFTHAIRDGREDLLAL
TQCTVLCERLIEEGVDALHFYTLNRPQMTRNVCYALGIVPEVSLQNVA
>A0A6N2XQC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster bolteae|TrEMBL
MKIRDILAEGKPTLSFEVFPPKTEDAYDSVEKAAAEIAKLKPSFMSVTYGAGGGTSDYTV
GIASAIKEEYGVTPLAHLTCVSSTREKVHHVLGELKERGIENVLALRGDIPQDGSTPREY
HYASELIWEIKKAGDFCIGAACYPEGHVESSNKSVDIDYLKQKVEAGCDFVTTQMFFDNS
ILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTYLPSRFMSIVDRFGDNPAAM
KQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A2W7A4D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp|TrEMBL
MLSPSFPSFHQAIQSGEFLITAEVTPPKGGDPSHMLAMANLLKGRVHGVNVTDGSRAVLR
MSSLAASVILQQHGVEAVCQVACRDRNAIGLQADLMGAHALGIRNILALTGDPVKAGDHP
NARSVFELESVRLLTLIHKLNGGIDFNDKPMPDGATNLLVGAAVDPQCGSWSGLQRRFER
KLAAGAQFFQSQLISDFDRLEKFMTQIAVGSNKPVLAGIFLLKSAKNAQFINRCVPGVHI
PDEIIDRLGAAADPLHEGVVIAAEQVRLARELCQGVHMMAVKREDLIPQILDLAGIPPLE
QSRDQELDIRS
>A0A5D9DAJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas eurihalina|TrEMBL
MSAQQSPLDISFEFFPPNTDAGRDKLMRARDALATRDPRFFSVTYGAGGSTQHRTLSAVK
AVRECGIDTAPHLSCVGSEKAQLRDLLKRFQEDGVKRLVALRGDLPSGMGGVGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFDRDLENFARKVHAGADIAITQYFFTAEAYF
HFVDRARALGVEAPIVPGIMPITNYAKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAF
GEEVISGLCQRLLDGGAPGLHFYTLNQAEPTLKVLDNLRT
>A0A5S5D282|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium composti Yoo et al. 2007 non Ten et al. 2007|TrEMBL
MKIVDHIKNANGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYLYKQ
HESGLLERVAYRKRPGTVAICAAIMSKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDPDFVPTPGGHAYATDLLQQVVDMNQGKYLHEDIESSEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVNKCRDNGIHIPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSDAVDACKTNADVRQVGEEWLVNQCKELIKFGAPVLH
FYTMSNPGPTKKIVERLA
>A0A372FFJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emticicia sp. C21|TrEMBL
MAKVTEHLSNTQGKPVFSIEIIPPVKGSNIDDLLKSIEPMMELKPPFIDVTFHREEYILK
NLPDGGTKEIKIRKRPGTVGICASILHKFGIDPVPHVLCGGFTKEETEDLLIDLNYLGIE
NVLALRGDYARPYNSFKAKKDGHFYANELVSQINDMNNGKYLHEEAEYLNASDFCIGVAA
YPEKHFEAPDLDQDIVNLKRKIAAGADYVVTQMFFDNQKYFDFVNRCRAEGITIPIIPGL
KVLATKKQLSVLPKLFYLDMPEAFRKEVDACETDKQAKQLGIEWCVQQCRELADFGVPAL
HFYTMSKSDTTLAVAKQIF
>W0J635|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutaceae bacterium TAV5|TrEMBL
MSSDRPISTLFPDHRPLRSLEFFPPRDDAGVESLRAAATALRKVPWDFVSVTYGAGGSTR
QRTTQVSRILKDELGFTVMPHLTCVGHSRAELDTLADRIHADGFRNIMALRGDPPKGDTT
FTPAPDGLRHASELVELLKRRHPDFCLGVAGYPEKHPEAATFEADLDALKRKVDAGAAFV
TTQLFFDNAIYARFVEKCRAHGIHVPVIPGIMPVLSIKQIQRITSLSGTRLPAALSRRLE
VAAEDPDVVEVIGIDWALDQIRGLLALGAPGYHLYILNRAKSALALAAGLAA
>K2PQV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor indicus C115|TrEMBL
MPQSRFSRQPDTAGKLRVSFEFFPPKTDAMEARLWETVTRLAPLSPAFVSVTYGAGGSTR
ERTARTVKRILDETALTPVAHMTCVDATREEVDQVIAEFVDMGVSRFVALRGDPSAGLGE
AYQPYPGGYANGAELVGAMRRQGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDVYERYVERVRRAGIYIPIVPGILPVHNFTQVANFAGRCGARVPAWFAERFE
GLENEPEIHALVASAVAAEQVLDLIERGVDDFHFYTMNRAELPYAISHMIGLRPRGGDAV
ANQPAAA
>X0IJF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. conglutinans race 2 54008|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>F2G6A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASREELKQIAKDYWDSGIRRIVALRGDLP
PGLEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDIDLVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGA
>A0A0Q7TJE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudolabrys sp. Root1462|TrEMBL
MTEPMTTLQQKLNAGRFVITAEITPPVSFDRADLMAKAAPLKGLADAVNVTDGAGARPHM
GALSAAAILVEAGIEPILQLTCRDRNRIALQSELMGAAASGVHNLLILRGDDPSAGDQPD
AKPVFDLDARQLLETARKLRDGNELPSGRKVAGTARFLLGAADSPIDPPAGWEPKGLAAK
VAAGAQFAQTQFCMDAGIAARYMARLAEHGIADKLKVIIGIAPLRSAKSARWMKDKLFGT
IIPDAYVERLEKAADPVAEGKAIAVDLIGELAAIPQVAGVHIMAPNNDAAVPDVIRAARA
GIKRLAA
>A0A7W7QZU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora kifunensis|TrEMBL
MALGTPSTRTDRALTVRELLAAGKRSYSFEFMPPRSEAAEHKLWAAIRRLEALNPNFVCM
TYGAGGSSRGRTVNMVGRIATETTLTPVAHLTAVDHSVAELRNIIGQYADQGVRNVLAVR
GDPPGDPRAEWVRHPQGVSYAYQLVELIKSIGDFCVGVAAFPQMHPRSSDWDQDIRHFVA
KMRAGADYAITQMFFEVEDYLRLRDKVVAAGCEAPIIPEIMPVTNVKQLERFPQLSGSAF
PAALDARLRAVADDPAALREVGIEHATAMSERLLAEGAPGLHFITLNGSTATLQIYQNLG
LHRG
>A0A8C8T6I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peromyscus maniculatus bairdii|TrEMBL
MHHRGAKVLPAEHCYPSLGTWASEAGCGRLSVPRSISRNPAMVNEGSSSGSEGSKDSSRC
STPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVD
VTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCQQRQEEITGHLHRARQLGLKN
IMALRGDPVGDHWETEEGGFSCATDLVKHIRNEFGDYFDICVAGYPKGHPEAESFEDDLK
HLKEKVSAGADFIITQLFFEASTFFHFVKACTEIGISCPILPGIFPIQAYSSLRQLVKLS
KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV
LKQLGMWTEDPRRPLPWAVSAHPKRREEYVRPIFWASRPKSYIYRTQDWDEFPNGRWGNS
SSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNQHGHTVTC
LPWNDDPLAAETSLMKEELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAY
LEFFTSPETVEALLQVLKKYELRVNYHIVDVQGKNITNAPELQPNAVTWGIFPGREIIQP
TVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDSCL
WQVVEDTFEL
>A0A6H1K580|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. RPA4-2|TrEMBL
MALGSASTRTDRARIVSDMLASGKKTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVSHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPQLSNASF
PDVLKERILTAKEDPAAVRSIGIEFATEFCAKLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>D7GQF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|butyrate-producing bacterium SS3/4|TrEMBL
MNLREYLKTTNLITDGAFGTYFAAKYQTQDIPELTNITAPEKVKKIHEEYLNAGAKFIRT
NTFASNTETLQEDFAEVEKNIQAAVEIARDAVNGRDAWIAGDIGPIPVNGTEDAAAAADE
YYQIAKTFAECGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIGELSSWDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLNVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTKEDAARLRRIKEETGATILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>A0A3N4SP29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ag109_O5-1|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVDHSLAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDTDVRHFVD
KCRAGADYAITQMFFQPESYLRLRDSVATAGCETPVIPEILPVTSVKMLERLPKLSNAAF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A0Q5FA56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Leaf311|TrEMBL
MTTTEAGHHTTGNFKLSFEFFPPKNPDMDVQLWETVEELSRWNPDFVSVTYGAGGTTKAP
TLQAVERMISVAQLPTASHLTCVDASKQEVHDVVRELREAGVKHFVALRGDPSTGIGTDY
KPHPKGYENAAALVRGLREIADFEISVSAYPEKHPQSESLAVDIDMLKRKADNGATRALT
QFFFDNDIFERYMERVTKAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPAFLDERFAGA
DEDPVARARIAADVAAEQIADLQKRGVNEFHLYTMNRSALVNAVLENVGYRPARKSAA
>A0A1Z1FDH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceicoccus marinus|TrEMBL
MSKPLFASLPGDIDVSFEFFPPKNDKSEEQLWDTVLALAPLRPDFVSVTYGAGGSTRERT
HGTVARIIRETGLPTAAHLTCVDASRDEIREVAEGFWNAGVRHIVALRGDPPTMGDRFVP
HPGGYASAADLVAGLKDIAPFDISVAAYPETHPEAQDSQADIDNLKRKLDAGASRAITQF
FFAPEKFLRFRDLAAAQGIDAPILPGILPVSNVAQTRKFADACGAEIPKWMEELFEGLDN
RPESRKLVAATIAAEMCRTLYAEGVRDFHFYTLNRAELSYAVCHLLGMRPREAALVQENA
A
>A0A430R5H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus|TrEMBL
MKIRDLLKARKGPLFSFEFFPPKTPEGEEALFRTMEELKVFRPAFVSITYGAMGSTRDRS
VLWAKRILDLGLNALAHLTVAGQSQEEVAGVLDRFVEAGVENILALRGDPPQGERVFRPH
PQGFRYAMELVAFIRSRYGEGVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRMGIEIPILPGIMPITSYAQLRRFTEVCGASIPGPLLSRLERYQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNRSPATRRVLERLGFKPT
>F8GKE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas sp. (strain Is79A3)|TrEMBL
MESQKKFSPTFSFELFPPQTPQGIEKLRLTRKQLAQCNPKFFSVTFGAGGSTRDRTLETA
LEIQAEGHVVAPHLSCIGSTQQNIRAILEKYHQAGIRHIVALRGDLPSGMAQAGEFRYAS
ELVAFIRQEFGASFHVEVAAYPEYHPQARSAQADFENFKRKIETGANSAITQYFYNADAY
FHFVDLCESAGLNIPVVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLEGYSDDSASIQA
FGLDIVTDLCERLLQAGAPGLHFYTLNSADLTSMIWQRLNLKGNTV
>A0A1H3WRB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrimonas cliftonensis|TrEMBL
MHDPARRAPTISFEFFPPKTPTAAQNLWRSVERLAPLGPQFVSVTYGAGGTTRERTLAAI
AAIRERARLDVAGHLTCVGATREETLQVARSYRALGCARVVALRGDPPKETGVFAPHPDG
FGGSVELIEALAREGGHRITVGAYPEKHPEAADQRADIDHLKRKLDAGAENAITQFFFEN
ATFLRFRDACAKAGIDAPIIPGVLPVENFVKMRHFAEGCGASVPDWMTSAFENAADEEAA
RDLAVSIASEQCAQLLAEGASHLHVYTLNNPDLPFEVCRAIGFEPQPTRVAAAGGA
>A0A248JPV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirillum amazonense CBAmc|TrEMBL
MTTANETAVTETAADTPLARQLGGGEPLVTVPRDLRVSFEFFPPKTEKMEQTLWQAIRRL
APLSPAFVSVTYGAGGSTRERTHATVTAIQQQTGIPAAAHLTCVAATKEEIDTIARAYWD
AGIRHIVALRGDPPQAADGSGGLGGSGYQPHPGGYAYATDLVAGLKRVADFEISVACFPE
THPEAASAAADIDNLRRKVDAGATRAISQFFFDTDRFLRFRDTVAAAGIDIPIVPGILPI
TNFGRAVELGAKCNCAVPAWMDELFGGLDAEPETRQLVAATVAVQQCLRLEREGVRDFHF
YTLNRADLTVAICHMLGVRAPKAV
>A0A1V4AMV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyramidobacter sp. C12-8|TrEMBL
MNNAFEEMLPNFSFEIFPPKRTGSLESIYDTVDALASLRPDLISVTYGAGGSNRDNTIEI
ASTIQNRYMLPAVAHLTCVGSSLEQTDALLAELKEKGVRTILALRGDRRADADFGDGYFK
HAAELVAHIKKNYDFRVLGACYPEKHPEAPSLEADIAHLKEKVDAGVDALITQLFLNNDD
FYRFRDLAQKAGVNVPIIAGIMPITQASMLDKVVSLCGASIPPAVRRFVDAYGHNAEAVR
EAGIAYAASQIVDLLASGVEGIHIYSMNKAGVTRQIAQNIHGILYSLRVKRS
>A0A855U0M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus haemolyticus|TrEMBL
MSRLLNQLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVESIHRSYIEAGADIIQT
NTYGANFEKLRRFGLEHKVKDIHKAAVAIAKRAARPDTFILGTVGGFRSLQQEELPLSTI
QYHAENQIDTLVEEGVDGLLFETYYDLEELTNIVTTTRRKYDIPIIAQLTASNTNYLVDG
TEINKALQQLVACGANVVGLNCHHGPHHMQRSFSHIELPETAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPQHIAYIKSSVKDLKPVKNKNIIPINRQT
NRAVTHTYKHNLTTKVKNGPTVIVELDTPKHLDTDLFFENIGKLDEANIDAVTLADNSLA
TVRVSNIAAASIIRQRYNIDPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMNYFITQPVYSKEKIKEVYEATKHLNVPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLSQFKAVKDDKEKTKALSLRLSKELIDTVHEYFNGLYIITPFQRIDYSLELAAY
SKAITQNKEAIS
>A0A7Y0X4L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio parahaemolyticus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDATRSELIEIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRAAVEA
>A0A496QL07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteria bacterium|TrEMBL
MINASYGEDKKITQSPNHSITKSPNHQITKSPPGSLYSKLQKAMEERLAQRDFGYDVKGT
KRNFVITFELVPARASKGKAIDEILQFAKEAAADGLISALSITDNAGGHPALTPRALGSE
IMALGIDPIIHFSCKDKNRNLVESQLFVLDRSGLKNLLVLTGDYPRYGFMGNAKPVFDLD
SVQVLDMISHMNQGFVLDSRAPFGGVKLAPMDFHAGCVVSPFKRLESELIPQYLKLKRKV
AAGASFVITQMGWDVRKFDELRRFMDREGLRVPLIGTVFIPTTGLAKTLCRGEIPGCILP
DRLLERMEQEAISDDQEGDPRLERAARLVSILKGIGYEGVHLSGPGLKYSHVRWVIERAN
DISERWKLFTCQFLFPEEWKFWYFKEDPETWLNYDKPTPGSEVSLSLRDSLGLSLGRLFH
ELAFEPGKPLFNSLRRIAGWIDGSSSKKHFTSFEYWLKEWLYDCRRCGDCALGEMGFLCP
QSQCSKFLLNGPCGGSRDGWCEVWPGRQRCFYVKVYERLQSLGKQERLGGPRIPPREWTL
DSTSSWLNFYLGRDHHGIG
>A0A6I3US25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
ILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQ
SLG
>A0A6G4YCI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 196(2019)|TrEMBL
MALGTASTRTDHARTVRDMLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVTYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A822FWN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
NFGVQACLDLCCALLDSGKVNGLHFYTLNREFATIEILKRLGLWLDEQSLRALPWKKTSF
SHARSQENVRPIFWSIRPKS
>A0A3M7MZ60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetothyriales sp. CBS 135597|TrEMBL
MMPCIASQEVIMDLTELYFEIVYPIFPFFHRPSWIHRISRAQYTSDRELYAATMAVCALV
SSRVRDGAVTNPKWDVARLRQPRPELFYAEARNQLASLDTVASLNVLRARAVLAIAAIQN
GDMREMRWQLGTYFTLVAVDGLHDEANWPTGIGVVERQERRRLFWSIYTLDIFTSSVSNR
VVVSREEQCNVLYPVEINDELIMDGTDLPETIDSSDQLWRKRPSLQVQSECWLSGWNFIT
DVYRILEHALSKFRNVRTHKQRSRSVLHDIFPDSSTLTEATVQDTVLEMYKRLPPCFREI
PEITYDIEKDRVSFQAANILGSVQLLRIVLCVAGDTSIEYRCRVAGDVVDALVKTPVAYS
LAISAPLLHHLSGIGVILGSVLEKPLSESDYTKVRSIVILMGQMLEKMEPIQHAAGASEK
LRNMVARIDAYALSWRPLASDRDGINPPPEFFSTVAVTPSSLAEPFFSLEFFPPKTQAGF
TNLRSRLSRMATALRPLFVSVTWGAGGSTASKSIELAEVCQCQLGLPTNAKFAWAVDLIR
YIRQKHGDYFCIGCAGYPEGFPPETQAHPQTQSPEHDLPYLAEKVKAGAQFIVCQFTYDF
EAYARYESLLREYTDHNGKKVLQNIPVLPGIMPIQNYSMLKRICKLTHVTIPADLSAKLE
KVKHDDDAVKNIGVQVLTDLVNGIRNLPAYNLDRGFHFYTLNLEKSCVSILDQAKLIPPL
REATPESSSDSDVLTDGPASIQPPQHAHFSRRRASSINAQAHNRVIISSPTSDTSPSIAL
PKSQHEAPDRGVGIPASDPTREQELLISKGHGSLGREATWDDFPNGRWGPAHSPAYGEID
GYGPSLKVGPLTARKLWGHPKSADDITNLFQRHVLGQLEAIPWSDEIDGDAAGAPGAGVL
RAETRVIRDELLGLIGKKHYWTLASQPAVDGIRSDDPTFGWGPQRDGFVFQKPFVEFFCL
EDEWVKNLKPRLQTFPPEKVSWMKIDASGRYESSSEISSSTTIATTTSAPISSSAAKTSR
ENARGNTVTWGVFPGKEIVTPTFIESESFRAWSDEAFAIWAEWRCCFPRGSEEEKFLERM
RQNCVLVNVVGHDYIGGASGGGKKLWEILLAD
>W4LUV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Entotheonella factor|TrEMBL
MMNRDTFKQRLENGPLLLDGAMGTLLYGKGISIDQCFDALNRREPQAVASIYRDYIDAGV
DVLETNTFASNRFKLAEYGLQHDVLELNTAAVSIARRVIDASFKPILLAGAIGPLGIRLA
PLGRVRMPEAKAAFREQIEALVGADPKGVDLLILETMADLKEVEAAVDAARTIAPELPIV
AQMAFTHDDRTFIGHTPDEAARKLSSFDVDMIGVNCSSGPAQVLRLISIMKEVAPDTPVA
AVPNAGWPQQTEGGRVMYAATPEYFASYTRAFREAGAGLIGGCCGTTDMHIAAMRQALDT
PGDNTIPLPRVKLLQRETAVTAVAEQPTQLAQYLNEGTFVITVEMSPPKGIGAERLLRRA
SMLKDAGANILNLADSPLARMRMSAWAAAYLVQQEVGLETILHFPTRGRNLLRIQGDLLA
AHAMGIRNLFVAMGDPTRIGDFPEAMDSYDIVPTGLMQLITQQFNAGVDKSGNRIDQATS
FVAGCALSLTPKDVEREMTLLRKKVRNGAGFALTQPVFDVAAARAFIDTYEARYGEPIIP
ILAGIKLLHNDRNADFLHNEVPGMIIPQAYRQRMHNADNPQQTGVRIAQEMMEEIKPFVQ
GVYFMPNFGRYDLVAEVIGGSR
>A0A4J1VML1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLSRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A6B2XS48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID13726|TrEMBL
MALGTASTRTDRARTVRDLLASGSPSYSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSV
TYGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLAVR
G
>A0A6B2W4H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID13588|TrEMBL
MRTLLQRVRYEVLPAGPTEDQVLAHVPRDVVITVTASPVKGLDPTLDLTVRLAGHGYRVV
PHVPARLLRDGAHVAEIADRLRASGVEDVFVPAGDANPSAGAYEGALPVLRQLSELGSPF
RHVGITGYPERHPLIDDDITIQAMWEKRVHATYIVSNLCFDPQVLGEWVGRIRRRGVALP
VHVGVAGPVERTKLLAMATKIGVGESTRFLARHASWFVRLSAPGGYSPERFLTRTAPALT
APSAVVAGLHVFTFNQIAETERWRRAMLERADN
>A0A818RFT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MASYEEDLRYLKEKVDYGADFIITRLFFQPATFIKFESDCRSIGIQCRIIPGIFPIQAYA
SLKNIVRLAKLDVPEELLACIEPIKYNGEAIRNFGVQKCVDLCRTLLDSGKIHGLHFYTL
NREYATIEILRKLDRCVRPKSYFHRTSNCEEFPNGRWGLSFAPSFGALTDYHLFYIKIDA
TRDALLDEWGHELADKQDVRRMFACYIADEKNGRVKIVHHFPWKDEAISPETNFIHDHLI
KYNRKGILTISSQPAVNGKSSTDSIFGRSIKKWLCLSKSLFRIFTSEKKIPALRAVLKTF
PGVNYHFVNKSGEVNETSTEGEQPIALIWGVFAGREIIQPTVVGPISFMIWKAIDLSARL
INDYFSIL
>A0A5N4W3B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter tandoii|TrEMBL
MPLLTDSLQNQPFSIFLEYLPTKHAQLVPSCIAGYPVTMTIADRVRSDDDPEPLAIAQNY
AAEIPKILHFSGKGRDIADFNEFIRAIQEQGYSNVLLLTGDKLKHHQDGQDVNLPRTRYL
ESVNAVMQAKKLAPQIKVGVALNPFKYTKAEHDAQYFKLDKKVQAGADYVVTQLGFDLDA
LKEAKQYLDKLPSCLDLFACVMPLTAARAEFMVKHKVAGIVLTPHLLQLLKHEQSIDAAI
AEQNVYARCALQILICRFWGFAGVHLSACHKAEEQKKLEQALERFQDFSFERCIQIWSEL
HQLKSGDELKPKPDVFQKKVSSEQMLKYKSMQFMHDSMFDSKIARNVGRKLFNLKLWSGH
FANKLLIKSEYLSKHGVVGCESCGQCRLADTLYICPETCPKGLANGPCGGTTLDQCEFGD
RECIHSVKARLAEQTNQIAILKERLIDTVPIELRGTSSWVNWFNPK
>A0A2I5KHG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEISVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCALADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A420HAA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Golovinomyces cichoracearum|TrEMBL
MEKITDKIAALPPGSNFFSLEFFPPKTNMGLSNLRSRLDRMARALRPLFVTVTWGAGGST
ATNSLELADLCQRQLGLTTCLHLTCTNSSQVLIHKTLEAARVLGIRNILALRGDPPRKDT
EIVNSEIESPTEFEWAIDLVRYIKKNYGDFFCIGVAAYPEGHADGSDPDGQSLESDLPYL
IEKVKAGADFILTQLFFDTGAYDTFEKRLLEHESGCFKKLPIIPGLMPIQSYQMIMRTLK
LTHVKMPSDVIAYLTSIKGDDELVKKAGVEIVSKIVSHIQDSPAPPIGRRGFHFYTLNLE
KAVSFILEKTSLIRLSHSASANDNSISNFTNIESSAFPTNPNINNHTDHLEHQQSSIISD
SSNTVSNTSPLKSQPQVEVILSETNRFSNCIENRASTLAISKGGDPLGREATWDDFPNGR
WGDARSPAYGELDGYGINIHLYLNQAIRLWGYPQSTNDITSIFTNYIKGSLGAIPWSDEP
ICRETDVIKDQLLKLNEKGWWTIASQPVINGIKSNDDVFGWGPRNGFVFQKAFVELFLSS
EDLLQLQAKVKKMDMANKISWYACNSKGEFSSSDTLAKSSSNNRGSINAVTWGVFPGKEI
VTPTIIEEISFRAWAEEAFKIWAEWGKAYTGSSPTSPDFQKAQASHQLINSLREEVWLVN
IIHHGLIEKDGLWDLLIG
>A0A6B2X7N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID13726|TrEMBL
MALGTASTRTDRARTVRDMLASGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWLAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVTHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCATPVIPEIMPVTSVRMLERLPQLSNAVI
PSALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A166GZZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halioglobus sp. HI00S01|TrEMBL
MAKPRISFEYFPPKTDAGKDKLLNETTPALNELNPEFFSVTYGAGGTTRDTTLGVVSTMR
EAGVDVAPHISFGGDDEDTMAELLQTYKARDIKRLVALRGDMPSGMGTAMQLVHANDLVA
FIREKTGDHFNIEVGAYPEIHPESKSYDSDIHFLKKKMDAGANSAITQYFYNVEAYFYYL
DQCMAAGIDKPIYAGIMPITNFENLARFSRNCGAEIPRWICQKMEGYGDDLESVRKFGLE
VVTQLCQTLMDSGCPGIHFYTMNQVEPTREIYNNLGL
>A0A2X0TYA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schaalia odontolytica|TrEMBL
MPFSDDAYACPCTHDHEPTLLSFEVMPPRKPSLEEPFWKTVDELLRVRPDFMSVTYGAGG
KDRSNARSTVHRLVRDTPIQPIAHLTCVGNSTDEVVSAVYDYLDSGVRTFLALRGDPPVG
QEDWEPGPSGVASATELIHLIRTVEKRRCDAHPGEALRSAFKPLTIAVAAFPAGNPAAGT
TPAQEVERLLVKQAAGASFAITQLFWDADVYSSFVDRARRAGVTIPIVPGLLPATDPARL
RRVQDLTGIEVPEYLLTTLADYPHQDARDEFGAVFGSRLIHSVLEAGAPGVHLYTFNRSK
PVLDILALMGVTPDPLRSQDCAPDTSA
>A0A3A8A9H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceaniradius stylonematis|TrEMBL
MTGSVFSRTQRVALNDDIRVSFEFFPPKNEAMAATLADTIEKLAPLNADFVSVTYGAGGS
TREPTQRTLAHVQKQGGMDAAAHITCVGSTRDETDAVIREFAAMGIRRFVALRGDPQTGM
GTRYVPHPGGYENAAHLVAGLKAFGDFDISVAAYPEKHPESPDFATDIDMLKRKVDNGAA
RAITQFFFDNDGYERFVERVRRAGIYVPIVPGILPIHNFRAVSNFAGRCKTHIPAWLAER
FEGLENDPQTHALIASAIAAEQVLDLVDRGVRDFHFYTMNRPDLVFAVCRLIGVREEHVD
AAA
>A0A5S3RAQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. S2755|TrEMBL
MALTLQEKIIDPNQGVYLIGTTPPKIGTDPEQLKSIAAKLLGRLHEIEYDGVIIYDIQDE
SSRTQVPRPFPFKHTVDPCEYSQLIRELSHLDVITYKSVAQRDSEAFSNWLSSTKQQYGL
NNLVLVGSPSSQGDIKLPLSEAYDVLKHHQDDFFLGGVTIAERHASKRNEHERLIDKTEQ
GCQFFVSQAVYDAQATIDLITSYARTCKQQGQKPKRIILTFTPCGGEKTLQFMEWLGISV
PEATKWRMLDSENTLSESIRICRENLDQILKSCSHLDISLGLNIESLTNRKEEIDASINL
YRLLKATMELCLAEKQIA
>D4LA53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus champanellensis (strain DSM 18848 / JCM 17042 / KCTC 15320 / 18P13)|TrEMBL
MELSTKKTRPRLTFEIYIPEQAAPISKMMQTVDVLRSAKPDFVLATADHRHGTGLERAVE
FASMIQSEGGIPGAVLIPSICYTRTRLKLQLQQMKRRGITRILAVRGDGMRPDFEHADFP
SAAELIEFIKEVDPEFRVASGCFPENHPESLGIVTDVWQLRRQADAGACRMITRMFYSFR
YFEAVQNRLEIAGVYLPMDAGIMPILRKEAVSLLRQDFGVRLPRSFAQRLAQYEDDPKGF
YEEGVKYANEQIRRLVATSAPGVHIFSHNDSELITRLSHGFYDAVSDFQAGTLAQEFLSK
A
>K2MDX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum IPLA 20015|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIANTIH
GEYGIPAVAHLTALYSDEAKIDEALDMFEAAGVSAVLALRGDYIDGEEPVGRFNHASDLA
AYIHDRKPGLKVFGACYPEGHYSAASLDEDIGNLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGAKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGII
YASDQIADLVAHGVDGVHLYSMNHPATTRRIWHNVEPLFTVE
>X8I4Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium sp. CM1|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSLEKPDYISVTYGAGGNTKGKTV
EIADRIKRQNGLESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPIDRELEKGD
FNYARELIEYIHKKKGDKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLKKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRHE
>A0A3P8ZS59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Esox lucius|TrEMBL
MVNQVQTVDDTWRRCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESVLHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPIGTDWEEEEGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAQSYDEDLKHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKENDAAIR
NYGIEHAVGMCRMLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEKSVYEVFTSYIMAEPNQAGHKVMCLPWNDEPLAPETNLLKDELAKVN
RRGVLTINSQPSINGKPSSDSIVGWGPPGGYVFQKAYLEFFTSSENVTALLQVLKKYEPR
VNYHIVNVQGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDVNPLEQPVEQE
ME
>Q6FA42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)|TrEMBL
MSKRTPISFEFFPPKTDAGAEKLRTVHQELQRLNPEFFSITYGAGGSTRERTLAAINDFN
GQGTPVAPHLSCIGDSKLRIAELLDLYKRQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFQIEVAAYPEMHPQAENFDADIKRFIEKVNAGANAAITQFFFNPDSYFYFV
ERIQKEGIHIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDTQSIKAFGHE
VILKLCERLIDGGAPSLHFYSMNNTEPTRQLVIDLGLN
>G1V3W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bilophila sp. 4_1_30|TrEMBL
MNIGQLIAERGKPFYSFEFFPPKDPDQWPDFFKMAERLAPLEPLFTSVTYGAGGSSQDAT
LEIVSHLKKEFQFETMAHLTCVGATQDYITQYLQRLRDNGVDNVLALRGDIPKGQDIDWE
TAEFRHAADLVRFAKAHYPDMGIGVAGYPAPHPESPSFASDWRYTVAKIREGADFVITQL
FFDVREYLHFVDRLSDMGVSVPVIPGILPIQSLESIRRTLSLCGANIPGKLYLALEEANA
KGGAEAVREAGLKFAVQQIRTLLDNGAPGIHLYTLNKASMCLRIAEEVGAL
>A0A316BGH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcaceae bacterium R-25|TrEMBL
MKINKILADKTPTISFEVFPPKAETGLNDVKTAAGAIAALGPSFMSVTYGAAGSTSKLTV
EVASDIQNLHGVPVMPHLTCVASTKEHVANMIRQIRENNIDNVMALRGDLPKDGNVCHDF
EHASDLVREIRSLDPDICIGGACYPEGHIECAHKSDDIHFLKEKVDAGCDFLTTQMFFDN
NIFYNFLYRVKDVGINVPIVPGIMPITTAKQLSRSVQLSGTSVPERFKAIVDRFGDDPVA
MRQAGIIYASEQIIDLIANGITHIHVYSMNKPDVASDILYNLKGIIG
>A0A3E2WCK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi|TrEMBL
MKTTEIFKKHTVLSFEVFPPKRTGAVDTIYSTLEELQKLHPDFISVTYGAGGSENCKATL
EIAAAVKNNYHIESVAHLPCIGLSKEDVLSQIRHFKEAGIENILALRGDIPKDGEMSGDF
RYAGELIAFIRERCSFNVIAACYPEGHTESETIAADIRNLKTKVDAGADQLITQLFFDND
YFYRFRERCSLAGIHVPIQAGIMPVVNKKQIERMVSLCGVHLPRKFTAMMERYEHNPEAM
RDAGIAYAADQIIDLTAQGVDGIHLYTMNNPYIAAKIYEAVHRVLAA
>A0A3G2IFB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buttiauxella sp. 3AFRM03|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNYKQAHKFATMTNVRVPHWMAQMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPTI
>A0A1M4VX45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium takakiae|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTIGGHTSAMDLVHQINNLGRGKYLHNEDQECDEHNKFCVGVAG
YPEKHIEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVNKAREMDINVPIIPGI
KPIATKKHLKLLPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAITQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A257S6A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiphilium sp. 21-60-14|TrEMBL
MKMTPDLSLSFEFFPPRSEAARASLWSTLDALTPLAPRFVTITYGAGGTTREHTETTAAA
IAAQTGIPAAAHLTCVDTDRATTLATARHFWQAGLRHIVALRGDPPRAGENFVPRQDGFA
NARELVAALKTVAPFEISVAAYPDGHPDSIGADADLDYLKAKIDAGADQILTNFFFDPEA
FLRLRDRAAAAGIAAPVIPGIMPIVNVAQLRNFAQRCGLTIPPNFNQSLDGLDEQPDQRD
AFAINFALNLCQSLRAEGVRHFHFYTLNRAKLPHAICAALGGASR
>A0A0K2R3H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Hiyo4|TrEMBL
MSPPSLIETHPNLTESAPVALSYELFPPRSPAAAESLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPEELAEIIGDLLDTGVRGILASGRPAQGR
WTARRRVTAVCAGSDRTYPAG
>A0A1A2RPA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. E2479|TrEMBL
MEFGPCGGVRPDGQCEMRPSPCVFDDVVPWSGDRPTPRPARAPRVLTDFSATPFDPDDIA
ATAAILAPGCDAVLVGEHQNKPDFPPTLMASLLLDAGVTPWITLSCRDRNRVVLEQELRG
LRSINVDTVLCVTGDGRGYDVRPEVTQTFDLDGPRLVSLAASVGMAAAVPETPTAPPVHR
RPARLVEKQRAGASLAILNHVPFPDMVAGFMTAARSAGLTIPVITSVAVFTDSISAAVLE
NLPGLEIDPVVTQRVLSAADPVAAGIAAAVSEARALLAIEGVEGVNVSGLASASGPRVGA
EIKAEVGRRIRAEAPMTRVADDAERSDEEERRL
>A0A0L0GKV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trabulsiella odontotermitis|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVELLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNYKQLTKFATMTNVRVPKWMDAMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A6B9G2G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea cypripedii|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRSSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAHDYWDSGIRHIVALRGD
LPPGAGKPEMYGADLVELLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAIAV
>A0A1F8SL10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_19FT_COMBO_48_23|TrEMBL
MANSLFEEKIYSDVFLVTTEIGPPKGVDVSEMIHHIELLKDKVDAINVTDHQSSVMRFPS
LGGCLLVRELGGEPILQVTCRDRNRLALQADLLFAYSRDVRNVLCLTGDSIDVGDHREAK
PVFDLDSIQLLKAIRTMESGMDMAGNELKNAPKFCAGASVHPEADFIEPQLVKFDKKVIA
GAQFFQTQGIFDLGSLRRFMQYASQFNVKILAGIIVLASARMARYMNDNVPGIIVSQDII
DELATVEKGKGLQKGIEIAARLIKAIREEKLCHGVHVMAVGNEGIVPEILEAAELASVGR
>A0A1H1UN60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmoricola scoriae|TrEMBL
MSALKSVHKSVQRSVHKSAPLARRGQRADRDRAMRRLLTQTRYEVLPTATTEDKVVASVP
TDVAVTVTASPGKGLEATLALSERLAGHGYAVVPHLAARMVRDRVELVEIRARLREAGIS
SIFVPGGDAEPAGDYADAFGLLEDLATLEDPFVHVGIAGYPESHPTIADDLTVQAMWDKR
RHATHVVSNLTFDPATIRDWVARMRLRGITMPLLLGMPGPIDRAKLLTMATKIGVGESTR
FLAKHKGTFARLAAPGGFTGERFLRDCAVVAAQPSAGIEGLHVFTFNQVAETEAWRQKLL
SELPA
>A0A6I2LE56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter sp. MDW-2|TrEMBL
MTPPRPRQTDEHPDGIDLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSTSLLETVRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPYDFRPVHLGKKIAAGAQFVQSQYCFDVPMFRTFMNRVRDLGYDEKCY
ILVGVGPLASAKTAKWIRANVPGIHIPDTVIKRLEGAQDQKKEGKQLCIDIINEVKEIPG
VSGVHVMAYRQEEYVAEIVDESGVLKGRRPWKREARADDQRVAERLEHILHDDVTESQVD
MVKTAH
>A0A0F4WMZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. IBUN13A|TrEMBL
MIKEFLNNNILICDGAMGTYYSEKTGNDISYCEFGNLNDKNTIRRIHEEYIEAGAKLIRT
NTFSANSKELGVSRKTLKDIIESGIEIAKEAVYNKEVFIGASIGPIRENGADENVVEVLE
EYKFIVDCFLDNNINVFIFETLSNLDYLEEVSTYIKNKKPESFILTQFAVKPDGFTRDGY
SVSKIVGEVKKINTIDSYGFNCGSGPTHALELIKKIDIGDDIVSSLPNAGFPEIIHERTV
YPNNPVYFARKVKEIKKLGVSIIGGCCGTNPSYISKLRDTIDNKPEPGDKIKRYEHETYN
EKNIIKNTFKEKVKNGDFVIAVELSAPVDTDINKIMTGAKVCKDNNIDIVTVPDSPMSKV
RADSVVMSSKIKREIGIEAMPHMCCRDKNTNAIRSSLIGGHIEEIRNILAITGDPISDAS
RIETKSVFNLNSFKLIELINDMNNEVFTSDDIFIGGALNLNVLNKEVEYGRMMKKVERGA
KFFLTQPIYDDSAVEFLKSIKERTDVKILGGILPVVSYRNAMFLNNELPGVTIPQEILNR
FSEDMNREEGQNIGIDIAVSMGKKLKGICDGLYFITPFGRVNMIVDIVNRIKEV
>I0RBE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoanaerobaculum saburreum F0468|TrEMBL
MENIRDYLKNNILLFDGAMGTYYDELTDDGIGCELANIKNPELIKGIHNEYIEAGAKAIL
TNTFAVGIDVFNGDRKLQKEVIVAGIDIANNAAKDRAYVFADIGPIHMSRNELVFEEYKV
LIDIFLEKGIKNFLFETQSNTSGMVLSAGYIKKKCSDAFIAASFAVMPDGYSSEGYQYKA
LFAEVTDSGLFDAVGLNCVSGANHMAKLLRGVDTKGLYLFAKPNAGYPVVRDDRVYYSSL
ANYFANQIEDILDMGVNIVGGCCGTTPKHIELLKKSMSGKLIKPRRAIKSEKNTTQNIRL
NRFKNKLESGQKAIAVELDSPIDTNVNKFIENAKKLKLAGADIVTIADNPIARARMDSCL
LACKVRNELDFDVLPHMTCRDRNVNASRGLLLGANAMGVDNVLVITGDPIPNAQRDEIRS
VFEFNSVKFANFIKSLNEEVFESPMNICAALNVNSRNFSAELKKAKRKQENGVEVLFTQP
VLTKRAVENLKTARENLDIKIMGGIIPIVSERNARYMQSEVNGIYITDDIVEKYIGKERE
EAEEIALSMSKEIANEIYDLVDGYYLITVLNRVSLMERLIKTVKEVCEKR
>A0A2E5CGA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MCEGLPESFFFINFFQVIRSNFYYQLKSDNTIRTSIRKLNIFSQSLDIKDFTISSEIFLR
PDTDREAIRIQAELLKEHIDAILVTDNQSGQLHMSTLSAGIILKENGIDPIINLSCRNRN
RISLTSXXLGCASLXMXNLLXTXGEKIPKEVEPRPKAIMDMNADTLIXLANXIXXDEKLP
TNNDFXXGGVVTPFAPKXGWPAXNLTEKXXAGAQFVXTXTCLDMEIMKIXMXRLIATKLL
RXMHLIAGIAILXSADDAKWLRXNRPNVMIPAEAVSRXEXSXXXEKXGIKMXAEQLTXLS
KMPGVSGAXXIASNSVLNIPEAIALYEAQK
>A0A542GAH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. SLBN-122|TrEMBL
MSPPSLIDAHPNLSDTAPVALSYELFPPRSPAAAETLWTTIRELEATEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIVGELLDTGVRGILALRGDLPKD
ASAPASGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEEHDVEVLL
AKQRSGADFAITQVFFETRQYADLLTRARRAGVTIPIIPGVMPLTSLRRLNRLGELTGVE
PAPQLMARLAAADTDAERLRIGVDATVDLANAALDAGAPGIHIYTFNEHQSALEVLDKLA
LPRRSRPGSRRESSVRGQLAS
>A0A2M7LBV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium CG_4_10_14_3_um_filter_58_15|TrEMBL
MSEHPIHPNWERAPVGVTEGYSLEITAKDIDSLRDAAPMIADETPVAVTFLPGEEQGARV
AAAVAVRELGFEPMPHFSARRIASSDEFEDYLQAVVRDAGVRRCFLVAGDPPEPEGPYFD
SSALIESGAFERAGITAIGIGGHPEGHPVMTRQQSWEVIDKKIGEIERRGMAPLIVTQFG
FDPDTVLFWLQELRSRGVEVPVRIGIPGPAGIKRLLRYAKYCGVGASASVLAKYGISLTK
LIGSAGPDKLVDRFAAELGSEHGRVRLHFYPFGGIDKTVEWINDYNHRHGL
>A0A3N1YM09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caminibacter pacificus|TrEMBL
MLKEKLKDKIITLETTPPKSPTLNEMLKKLEDSKAYEYIDGFSTTDCPLSKLKYNSIIAA
YRLQEKFKKPVIATMTMRDRNKIALQSDLLGANDLGITNILALTGDPAKMSDQPNVKGVV
EGSSLLLLEIIRAFNNGMDYGGKEFKIKPKPITPFAVSNSYAKNFSTIERKIFKKVKNYA
VGIITQPVYDIEIVDKMIGIRNKVRKEFEDERKEFEIIFGFFPITRLKTAQFLHSHVPGI
YVPDKWIEKLIKAHKISEEEEYKVGLELSRNLFQKLLKIHPKIHIMTANRFEIVKELF
>A0A5C6XIZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. IC073|TrEMBL
MKVTDHINNANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYLD
KGNGLLDKRITRMRPGTVGICASIMHKYKIDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKDEPYFNAAKGGNAFASELVDQIASLNRGKYLHNDVQVEHHSDFCIGVAGY
PEKHMEAPSLVSDLRRLKEKVAAGADYVVTQMFFDNNKYFEFVKAAKEIGINVPIIPGIK
PLAVQRHLQVLPQVFKIDLPQDLIDAVDACKDNKAVRQVGVEFAIQQSKELLAAGVPVLH
YYSMGKSDNVQAIASELF
>A0A5E4V567|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea pneumonica|TrEMBL
MNDSLDNQKIMTQPSFSFEFFPPKTAEGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQG
TIDTVVEIQREGVEAAPHLSCVGSTKENIRDILQTYRSHGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGDWFHIEVAAYPEYHPQAKSPRLDLEHFANKVKAGANAAITQYFF
NADAYFRFVDDAKRLGVDVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
ESIRAFGLDVVTALCERLLADGAPGLHFYTLNAASATKAMWQRLGL
>A0A0F5Q3W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia epidermidihirudinis|TrEMBL
MLDDNLRASRQTADKRPDLQISFEFFPPKTDVMEEKFWDSVHKLAPLKPRFVSVTYGAGG
STRERTLRMVSRIKKDTGVDAAAHLTCVGATRDEVDAVVRGYQDAGINRIVALRGDPPEG
VGQPFTPHPEGYQNAADLVAGIRRIGDFDISVAAYPEKHPQSPDWAFEIDNLKRKLDAGA
TRAITQMFFSNSDYLRYVERARAAGITAPIVPGIQPIHNFKQISGFAGRTGASIPSWLAE
RFDGLDDEPETHALVASAVAAEQVTELLDEGVTEFHIYTHNRSPLALALARILGRRPTQE
S
>A0A1V2B5X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Flexibacter] sp. ATCC 35208|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMAFKPAFINVTYHRSEHMFKKR
SDGSFEKVEIRKRPGTVAICAAVMNHYNVDAVPHLICGGFSREETENALIDLNFLGVDNV
LVLRGDAPKNEPAFEPEPHGHRYAEELLHQVVNMNNGMYLEEDLQGGVKTKFCIGVAGYP
EKHFEAPNLATDMTYLKRKVENGADYIITQMFFDNQKYFDFVKKCREMGITVPIIPGLKP
MTTRKQLTVLPRAFHVDIPNDLANEILKCKTDKDVELVGTEWLIQQSKELKEFGAPVLHY
YTLGKPEVIRKVVEAVV
>A0A410W7U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium pelargi|TrEMBL
MPSIHARYQRPITDVIADTPPGLVPFSVEFMPPRDDAAEQRLWNAAVDFHDLGAAFVSVT
YGAGGSSRERTLRVAKKLAQHPLTTLVHLTLVNHTVEELQQILRDYADAGLSNLLALRGD
PPGADPLGPWEKTEGGLEYASDLIEMVRSLEETKHFEVGIATFPEGHFRSPSLEHDTEMT
VRKLRAGAEFSITQMFFDADYFLRLRDRLVACDPEQGAKPIIPGVMPITSIRSVKRQIEL
SGATLPDSLRRQLLEADERAKITGADEVRKVGIEITTQMVDRLIREGVPDVHFMTMNFAR
ATQEVLHNLGMAPAWGTELGHDALR
>A0A0F9HV82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MTNKLTISCEFFPPKTDKGIATMREVREQLSPLKPEFYSVTFGAGGSTQDNTLDAVVEIQ
QTHAITNIDAAPHLSCVGSTAERIRDMLNTYQSHGIKRLVALRGDLPSGMRDPGDFRYAN
ELVEFIRQETGDYFTIEVAAYPEVHPQADSAHADFINFKRKVDAGANSALTQYFYNIDSY
LYFLDRCQKNGIEIPIIPGIMPINNFSQLARFSDGC
>A0A852ZZ15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allostreptomyces psammosilenae|TrEMBL
MSLGISTTRTGRAATIREQLAAGTTSSFEFFPPRDDAAERRLWEAIRRVEMAGPDFVSVT
YGAGGSTRGRTVRVTERIASETTLTPVAHLTAVNHSIAELRNIVGQYADAGIRNVLAVRG
DPPGDPRGEWIPHPDGVTYAHELVSLIKGWGDFCVGVAAFPEAHPRSTDIDEDTRHFVAK
VRAGADYAITQMFFDVDHYLRLRDRVAAAGCDVPIIPEIIPVTNIRQIERFAQLSNAYFP
PELERRLQAVADDRAQVRAIGIDFASRMCERLLAEGVPGLHFITMNNSTATLEIHQNLGL
RRTIPGS
>X1JVA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
FPPKTEKGREKLPETAGTLKELEPDWFAVTYGAGGTTRELTMDIVDELQKRLQIPTMHHF
TCVGHSKAELEAIIKKMKEKNICNILALRGDAPEGVEHWEPAPDGLEYCYQLIELIRSYD
SFFSIGVAGFPEGHIDCPDKETDSRYLKIKIDTGGEFVITQLFFNNKDYFEYLERVRKIG
VTVRIIPGIIPITNYQQLLRFCKTCGATIPQRVHDIFKPLDGDAEATYKAGVQFAVEQCN
ELLEGGAPGLHFYTLNKVDPTREILNKIKR
>X1RZE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
AELEAIIKKMKEKNICNILALRGDAPEGVEHWEPAPDGLEYCYQLIELIRSYDSFFSIGV
AGFPEGHIDCPDKETDSRYLKIKIDTGGEFVITQLFFSNNDYFEYLERVRKIGVTVRIIP
GIIPITNYQQLLRFCKTCGATIPQRVHDIFKPLDGDAEATYEAGVQFTVEQCNELLEGGA
PGLHFYTLNKVDPTREILNKIKR
>X1SHL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
LEYCYQLIELIRSYDSFFSIGVAGFPEGHIDCPDKEIDSRYLKIKIDTGGEFVITQLFFN
NKDYFEYLERVRKIGVTVRIIPGIIPITNYQQLLRFCKTCGATIPQRVHDIFKPLDGDAE
ATYKAGVQFTVEQCNELLEGGAPGLHFYTLNKVDPTREILNKIKR
>A0A1V5FKF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division BRC1 bacterium ADurb.BinA292|TrEMBL
MSVTPPPPSLRNHPFMRALAERAVLFDGGMGTMLYQRGVFITQCFEQQNLLKPDLVRELH
AAYVRSGAEVLETNTFGANRIKLARHGIEPDEMRAIIQAGVRLARDAGGQKIWVAGSVGP
SGRRFGAPGDDGIDPARAHDLFLEHAGLLAEAGVDLLVLETFREMRELEAAVAAAREAAP
HLPIVALLTPDAEGNTADGLDLEQVARRLEALAPAAGGFNDGAGPDGMFHLMRRMAKAAP
GLTLAAQPFIGGVETIEDRTIHLATTEFTGVYARRMFREGVRVLGLCCGATPAHIKAMRN
ALSALQPGAQKSAGIQVVGPSEAEPVEQANRPVATRFARKVAAGEFVVSVEIDPPQGTDI
SKALESARKLRDSGRVDVINIADGPRALARINPSSMALILKRDFDMEAIIHYCCRDRNLL
AMQADLLAANALGLHNILLITGDPPKMGDYPDATAVFDVDAIGLTRIVTRLNQGRDLAGN
SIGEPTRFFQGVGANPGAQDINIEIERLQRKRDAGARYVMTQPVYNAEVFERFIERAAPL
GLPILIGILPLRSLRNALFLHNNVPGMAIPAEVLARMEAAPEGADQRRAGWEIAREALRR
ALPYVQGTYIMPPFGSAEDALAVLEALD
>X1P970|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKAVSNLERVLESGTFTVTGELGPPQSADPEVIREKARLLKGYVDAVNVTDGQTAIVRMA
SWAACLIGMSEGLEPTVQMTCRDRNRIALQMDILGMSALGMKNLLCLTGDHQSFGNHPQA
KGVFDIDGIQLLQIARNMRDEKKFQSGDEISVSPSLFIG
>A0A850HDH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altererythrobacter lutimaris|TrEMBL
MSGTYKQGLDPAAEARTAAGAPLFSDLPGDIGISFEFFPPKTEKMSQTLWDSVATLAPLG
PRFVSVTYGAGGSTRERTHEQVVRINRETSIPAAAHLTCVNATREEVNEVARHYWESGIR
HLVALRGDPPDGNGQYTPHPGGYENAVDLIGGLKKVADFEISVAAYPEVHPDSPDAQTDL
DNLKAKFDAGADRAITQFFFDPECFFRFRDKAAAAGIDAEIVPGIMPIMSFAAVQRMSSM
CGTAIPDWMAGLFEGLDERPEARQLVSATIAAELCRKLYAGGERNFHFYTLNRAELSYAI
CHMLGARPKAVA
>X0X2Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MALREALDKGKFAVTTEVGPLKGTDTTEISEVAEILNGKVDGVNVTDQQSAVMRLGSLAT
CSMLVDKGMDPVFQMTCRDRNRIALQSDLLNAHVFGIKNVLALSGDFPTLGDHIDAKEVY
DLDTEQLIWTINRMNEGYDLADNELQGKTDFFVGAVVKPVSDTEASFELQLAMMEKKIDV
GARFFQTQAVYDVDA
>X1J0A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSFSEKLKNGKFIITSEVGPPKGVNINKGLEEAELLKGKVDGFNVTDLQSSVLKLGSLAV
SHLLAMRGLEPIFQLTCRDRNRLALQSDLLSAYVLGIRNVLLLTGDHPILGDHPQAKPVF
DLDSVSLLKVASTLMEGKDMNGNELEGKPDFCLGAVVNPGADSLELQLIKMEKKIEVGAS
FFQTQAVYDLEKFKKFMKKASKFGVPILGGIIILKSAGMARYMNENVAGVSVPEKYIKMM
AEAEKEERA
>X0SUV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MDIPQALIDRLAKTPKAAQPEEGIRICSEIIEQVRDIPGVSGLHIMAVHWAESVPEIVSR
AGLYPRPGVKIEINKQVVL
>X1AQT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MQVINVLKKADKPVFSLEITPPEKGKSIQGIFDTIDMFKEFKPHFINVTYHQQKVVYTEK
KGIIKKIPKRKNVGTVGICSAIKHKYGIETVPHLICLSLRFHYIHFYPRSHQGLSFLLGC
WTL
>A0A4S3YFE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas atacamensis|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETADHFHIEVAAYPEMHPQARNYEDDLANFVRKAKAGADSAITQYFFNADSYFY
FVDRLQALGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTRSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A3M7BLS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMNYDADIFIEWAKKVRAAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAELFVKYMSGKVETLPWSEQPISPESNVL
TNDLVNLNSRGLLTINSQPAVDGMKSSHPVYGWGPNNGYVYQKAYLEVLIPPSLIAEIIR
RMDANPDITYYAVNNSGELKTNAPQDGGPNAVTWGVFPGKEIVQPTIVETISFLAWRDEF
YHLGSEWAKCYDEGSRSKNLIKEITESWYLVNIVDNDFRNMRGIFPLFDGLKVAGVEPVA
AVNGVAGVNGDVNGDVEKKEGSHKPEVNGVPDGNNAVNCADGAAVNGQVKN
>A0A3M7I4W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGVRNILALRGDPPRSDE
YNDPNNPLSEQDDSNRDFTWAVDLVRYIKKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLVEKTAAGADFIMTQLFFDVEAYNNYEKRLRSHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLSRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTL
NLEKVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSS
NRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPINSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSRDDICTIFRRHLKGEIEA
MPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSTDPIYGWGPKNGFVFQKPF
VELFLPSADWQRLKPILQSDDQVTYYAGNAAGEFQSSDENSVNPVTWGTFAGKEIITPTI
IEADSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDA
LIAA
>A0A2J7VRA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. B4|TrEMBL
MRLPLSFEFFPPKTPEGAVKLRAVRQQLYARRPEFCSVTYGAGGSTHEGTFGTVREILGE
GVDAACHFSCIGATRTTVREQLKELKAMGVKRLVALRGDLPSGYGMGGEFHYASDLVGFI
REETGRDFHIEVACYPEVHPQARSPEADLRAFAAKVSAGADAAITQYFFSPEAYFRFVEE
ARGLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TELCERLASGGAPAMHFYTMNQSVATLALLDRLGWEG
>A0A425VWJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriaceae bacterium|TrEMBL
MRIDDILKGKQTFSFEIFPPKGDMSVQQATAIADELTLNHPDWISVTFSAGGSGNSQHTV
GVAKAIQQAGKTQALAHLTCLGSSKQDVDAYVQAIKDAGVQNVLALRGDRVPGREAIDFE
HASDLVSYLKGTGLCVGAACYPEGHVESASLREDVEHLKAKVDAGADFLVTQLFFNNDDF
YRFRDLLVRAHIKVPVVVGIMPFTSVQQIQRMAFTCGASIPSKVIKRLVAAGDDKEAQRR
AGVAYACEQLVDLAQNGVDGLHIYTMNRPSIGRATHDCLLKAGYLKE
>A0A1I4SNG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodospira mobilis|TrEMBL
MKSQKRFERTFSFEFFPPKNDEGARKVREAWTQLAQLNPRFFSVTYGAGGSTQARTLETV
LEIHKSSGVDAAPHLSCIDSTAEQMRGILQMYKDNGLRHIVALRGDLPSGMRDPGEFRYA
NELVEFIRKETGDHFSLEVAAYPEIHPQAPDAFKDMDNFARKVKAGANSAITQYFYAPEA
YFRFVDDCERRDIDIPIVPGIMPITNYKQLARFSDTCGAEIPRWIRKRLEAYGEDTASIR
AFGEEVVTDLCARLLEAGAPGLHFYTMNQAGPIQAIWKNLGLKPEPK
>A0A7V2T248|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucothrix mucor|TrEMBL
MTTQKFSFEFFPPKTDKGIENLKQTRNTLAKLNPAFFSVTYGAGGTTQDCTLETVISIQK
ESGIDAAPHLSCIGSSKAQMRDILETYKDNDVKRIVALRGDIPSGMQDIGDFHYANELVS
FIREQTGDHFHLEVAAYPEKHPQAKSYEDDLKNFVRKVKAGSNSAITQYFYNIDAFNYFR
DDCEKQGVDIPIVPGIMPITNFTNLARFSDACGAEIPRWLRSRLDGYGDDTDSIKKLGAE
FVTEMCAKLLAQDVAGLHFYSMNRVEPSLSIWNNLGLSELK
>A0A3C0YUB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MQANGRKRLSQTLLKKDGFVIVAELVGGPNFNYTPIQKFLTAYNSSGGKDIPQGFNFVGI
ASPQSPGGVANIEPADVNRYLTTQNLLGDLDFIPHISCKDANADALTSLLAAHKAAGVES
VLALTGDKPVSSKGVFELESTGLLAKITRINNEAYLSAKVETLAQTKQFFAGAAVSPFKY
TEASQMQQYYKMEKKIACGAKFLITQVGWDWKKSLELVRYLKENNIDIPVIGNVYLLSTI
TPAPRLMHDIKLPGCFVSDELLAKVYSETVDQHIERAAQQIAMYKAIGAAGVDVGGVHDY
EMFIKILKRAAQIGTNWEQYKNNLCWPPIKAFYLYNDAGNRTQQSMYLKTANHRVFNFMH
RAILDPKHNGFHAFKKTLEFFGAKKGKGFAYKGFFMLEKPMKYCMFDCEECGDCYLPENF
GLCTIGGCEKGMDNAPCGDSTVEGKCGNNLERICIGDRIYKAAGAEKGGYEKLRKTINKP
RIPALEHSASIPNYLFSRDHTMKNAIINIGEAIHASIPKTGQIMQQLLALGDDCFNKPSP
EFEYIKALIESQAADGADYIAVNIDQFGESDPSLAVRLMKEYVKLVRKYSRGVPVCVDSS
DDNVLIAGLKEWYDTTEKVQPPLINSIKIYTIDNMMPLKKHYDYKFIGLLISEAKATTDN
VDDLYNLAKTIYNAAMKHGFKAEEIFFDSTVFPLAIDMPMQPGVPGYTYRTFNTIKKIKT
DPQLKNCHFSLGVTNSVRDLPARKIGVTRAYVEVAMRYGLDASIVNASHHLGNSPADADL
VKLVEAYADLDGSSEKLNIAM
>A0A3D4NE10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MTDKLSLLDRLKTGRPLLSDGAMGTMLHSRGITYEGCFDCLNLSHPGLVADLHREYIEAG
AQIIQTNTFGANRYKLGRHGLADNLVKINAAGVELARRAVLASFKEILIAGDVGPLGVPL
APFGRVQVDEARAAFEEQISALSAAGVDLIIIETMTDLHEVIEAVKASKSVAPKLPVVAS
MTFTRDNRTLLGDSPAKVAKGIHEAGADIIGINCSGGPNQLLNILKQMKSALPEGLFSVM
PNAGWPEQVEGRIMYSAGPDYFGDYAVSFWQAGACVIGGCCGTTPAHIKAMADKIEVTTS
VEVIAKRDTDKSQTEQESEEVFPPTQMAQKLRDGKFVIAVEMDPPRGLSTGKLIAGASLL
CQAGADVIDVADSPMARMRMSPWAVCSLVQRKVGVETTLHFPTRGRNLLRVQGDLLAAHA
LEVRNIFVVMGDPTSIGDYPGANDNYDLVPSGLIKLIKQGFNAGLDHAGTEIGQPTNFFV
GCALNLNPVDMESELKNLRRKIKAGADFILTQPIYNPDLVARFHEAYEREDGKLPIPLIA
GLLPLASARHAAFLQQEVPGIDIPAEVHQQMAESGTLGAKAGIRLTVELVEQIKDKVQGV
YLMPAFSRFDHAAEIIEQIRGNS
>A0A839ZBM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Angulomicrobium tetraedrale|TrEMBL
MSSDIERRSRRSGGRPIAVSFEFFPPKSAEMEATLWNSVQRLAPLAPKFVSVTYGAGGST
RERTHATVERIIKETRLAPAAHLTCVSATRAEVDEVVRGYWDAGVRHIVALRGDPPGGVG
QAYEPHPQGYRTTAELVAGIRRIANFEVSVSAYPERHPESASFDTDLDILAAKVDAGATR
AITQCFFDNDLYFRYLDKVRARGIDVPIVPGILPVSNFKQARNFAEKTGTHVPDWLSGRF
EGLDADLETRKLIAAAVAAEQVFDLVDRGVTEFHFYTLNRADLVYAVCHLLGIRPPQEVA
AGQGNGQAAA
>A0A7Y5VWY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHLLDAFNTRRTTFSFEFFPPRSESASADLFEHIREFEKLKPTFVSVTYGAGGSTRQITH
DLVVKLRSTTALDPMPHLTCVGHSGEEIDAILERYAQAGINKLLALRGDVPKDTPAGVDI
YKDLRQAADLVARVRKFNESGRHTERRGFTIGVAGYPEGHAETPNRMLEIERLKAKVDQG
AHFIITQLFFDNRDFYDFRDRCELAGIRVPIIAGIMPITSLQGMKKMAELAAGSRYPAPL
IRAVNRAGGNDESVRRVGTHWATEQCRDLLDHRAAGIHFYTLNKSTATRDVYATLGVQDS
LGLL
>A0A8D9YMX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae SK-93-1035|TrEMBL
MNYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDSVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A7X8Z020|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MRFSEICQHKDVTISFELFPPKTAEGEVKLFERTIPELLKLEPAFLTCTYGAGGSTREKT
LDIVSRIVKEVHYEAASHLTCVGASRADLVGYLEQARSNGIDNLVALRGDAPQGDDTFRP
HPDGFKYAVELVAFLKQLGGFDIMVAGYPEGHPECPDKHLDWQRCAAKVEAGADAIITQL
FYDLNDFYAFEDYLVNKLGVRVPIMPGILPILNLEQIQRFCSICGARLPEQLIQRLASYG
DDKQASRKYGVELATEMSAELLRHGVPGIHFYTLNRSDSTTEIIHNLGLLTNKSAS
>A0A7Y4XMA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclobacteriaceae bacterium|TrEMBL
MFLKKIKERESGVLLYGITPPKAQTSPEKVTEMAAKSLNILSSLDIDALVVYDVQDESAR
TAEERPFPFSSALDPFSYASTYLHTLDIPKIIYRPAGMFTKEELAAWLNGLKANRFYPVF
VGLPAPDYVVKTSLKEAYELWRNEHGDHSVIGAVTIPERHAVLKDEEVRILDKVDSGVSY
FISQCIFNVEYTLRILEDLTSACKSKNQQLPTIIFTLTICGSPKTIDFMEWLGIHIPDNI
KEQLKASTDPANHSVDLAVLVAKELIEYCQKKGIPFGFNIESVATRREEVEASLKLLSTI
TGLLKASGLRKEKAVVNVSNL
>A0A5J4Z6E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyridium purpureum|TrEMBL
MLVRVHVVRPANTARLHGYRGQYRMCTAEKGQKWRPGFVSLEYAGVYPRNAHLAEKLMTD
GSVQACIEPDLPLVSSWRRLLQQAFKAGVVPQTQASPLGTLRNLKASQKVFSVAAQTRSE
ASIRRKIHHAVNENGGARALLFVSGSSVLRKSPFMEYLSMDSVAMIGLAARMRAAGEIPA
HVEFWAVANPNVPSTKRNLELELVKIEEKIEAGATHVVTQPFLHLSHATQFWKAARKRGL
LERCDWHIGMGIFPTPAAYTFWLYLSGIQADAETRAHTQHIQQCLEQDGNTTAQVARLQW
IRSLQFLTDTLEVHQTERVCGLHVMPLRAHAFVPDLIHLARETQTKVSRSDAQREDSDHC
VGFR
>A0A7X9J711|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
VMQIAGRDRTRTGFQAEVLGAAALGVRNILCLTGDHPRLGPAPHSRKDIWDLDSIQMVWL
LRRMRDEGHFLDCREVKCAPQVFIGTAGSPYASTPAIQAMREEKKINAGAQFFQTQVVFD
LDAFNRYLEALDQRHLLERAALMVGITPVRSLRAAQAMAEVPGIRVPQHVFERLEKSADP
KEESVQMTLELIDALKKLPGVKGIHFMAVGWESIVPRLIQESGLRTQ
>A0A2M9KEQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02120-2|TrEMBL
MSGLRELLASGQRSFSFEFFPPKTDAGERVLWNAIRRIEAMAPSFVSVTYGAGGSSRDRT
VEVTKRMVAETTLLPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGNPNATWT
AHPQGLRHADELVSLVRASGDFSVGVAAFPEMHPRSPDWDTDIRHFVAKCRAGADYAITQ
MFFHVEDYLRLRDRVAAVGCDTPIIPEIMPATDARQIGRFAELSGAAFPEELAGRLEAAK
DNPADGHRIGVEYATAMADRLLAEGAPGLHYITLNRSTATLEIHQNIIESRSAHALAHG
>A0A4Q0I0H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetivibrio mesophilus|TrEMBL
MLKQKILDRESGIITYGITPPKKNNTEEKIKEISQKHIERISGLDIDGLVIYDLQDEKDR
NTENRPFPFIETVDPQTYSENYLKALKIPKIIYRSVGKYTPDQFCQLISPIPGQDAFSVF
VGAASRNQTVLLKLSDAYKISQDTNPGLVLGGVAIPERHMKNADEHLRIISKINKGCKYF
ITQAVYNVEAAKDFLSDYYYFSKNNNLKMVPIIFTLTPCGSTKTLEFMKWLGISIPRWLE
NDLMNSEDILNKSVSLSKSIFNELLEFCREKGIPVGCNIESVSVRKVEIEASIALVKDIK
YMMKGI
>A0A3M9KE87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora aurantiaca|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTPAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWIAHPEGVRYAEGLVRLVRDSGDFSVGVAAFPYKHPRSPDVDSDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFEQVADDPEAVRRLGVEQASEMCEKLLDEGVPGIHFITLNRSTATREVWQRLR
AAARV
>A0A369XGE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter phosphatis|TrEMBL
MTQNKRTFSLELFPPQTPEGAAKLRAARARMAALKPRFFSVTFGAGGSTRDRTLETVLEI
QQEGYQAAPHLSCIGSTRESIRSILEQYRANGIRHLVALRGDLPSGMARPGAFRYANELV
EFIRAETGDCFHIEVAAYPEYHPQAKNPQDDLQSFKRKLDAGANSAITQYFYNFDAYAHF
IDECQAIGIDLPIVPGIMPIAGYSSLARFSDTCGAEIPRWIRKKLESYGDDNASIRAFGL
DVVTGLCERLLANGAPGLHFYTLNQDALTAALWQRLRLS
>A0A0F2IBI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. S234-5|TrEMBL
MGYTHASHIGALNQNIAELSDNINVSFEFFPPSTPQMEETLWSSVQRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAQTGLVAAPHLTCIDANRDELINIANDYWANGIKNIVALRGD
IPPSGGAPEMYASDLVTLLKSLHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDDDPVTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKQA
>W0R6Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bibersteinia trehalosi USDA-ARS-USMARC-190|TrEMBL
MSYARTTDLLNQNLAELNGKVNVSFEFFPPKTEKMESLFWDSIQRLATLKPKFISVTYGA
NSGERDRTASLVKKIQQDTGIISAPHLTGIDATPDELRQIAKDYWENGIRSIVALRGDLP
AGYNKAPFYASDLVKLLKEVADFDISVAAYPEVHPEAKSAQSDLIYLKQKVDAGANRAIT
QFFFDIESYLRFRDRCVTTGIDVEIVPGILPILNYKQLEKMAKITNVKIPAWLHHAYQSI
REEDKSTAQIVGANIAMEMVKVLAKEGVKDFHFYTLNRADLSYALCHSLGVRAA
>A0A3D3UQQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MKIDSKLANAIENGDFILTAEYLPVAGTDSSGIESAAKVLDDSVLAVNVADNHYGVAMSS
LAASVAMLKSDVEPVYQIVTRDRNRIALQSDLLGAAYLGIKNVLCLSGYHQTLTGSPESA
NVYDIDSIQLVAAVRKLRDEGVLLDGTKIEGGFSMLIGAAANPYLTPIELNIIRLNKKVE
AGADFIQTQAVFDIEAFGQWLDAAVSEGVTEKIAILAGIMPLESAAEAEKLRETYTDLYI
SDELLERLKAAGDEQAQKKEGLAISAETIKKVKDMNGVRGIHILSGGKEAVVPELLAVSG
L
>A0A3A6H0I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. OM02-16LB|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A268TRT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. 12S02232-10|TrEMBL
MIEECVQKLLNTDFLSYEISPPKSPNIGEDLLTQLQDWKDFDALVCTDAPLAKFRQSSIL
TSLKLQNTLKKPVICTLNMRDRNTIALQGEILGANELDVRMFLTLTGDPIKLGDHPSAKG
VFEGNSSLLVKLIQNFNQNKDLNEHPIKGTLKTIYPFGVLNSYANNPLSLKNKMRRKINS
GIFALFTQPVYDIEIAKLLLQWLEEINTELGKNTGLVFGYFPILRYKTAQFLYSKLPGVF
VPQIWLEKLERAHSIGEKEEEKVGLELSKNLFEELKKLHNKIHFMNANKVALAKKITQ
>A0A197F4Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. SHUES1|TrEMBL
MTKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRGRTLDIVQALCA
RGDTDIAPHMSCIGDDKSQIAELLDLYKSLGITRLVALRGDLPSGQVGMGELPFALDLVK
FIRKHSGDHFRIEVAAYPEMHPQARSFEFDVDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTVAQPLVAGIMPITNSSNLVRFADSCGADIPRYVRKRLADFGDDRAAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVEALGLIA
>B2GHG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201)|TrEMBL
MSAPLTAVHQDLTAAGAAPSGTSWLVRRPRRSTLVSFEVFPPRPTTDPDTVWRSIDAMAQ
AGPDFFSVTHGHSGGRGVSREALRHLRRTTRTPVMAHFTCGGTDRAGLERSVEHLLDDGV
RDLLALRGDPPLGAGEWVTPPGGIGRASELVRLIRDVERRRFGDGFRPGTRPLSVSVACY
PSPARGRDFEADLASLWEKQEAGADYAITQVLYEPEDYAAFLERARSEGIHIPVVAGLMP
LTNPKRLQRMTEITGVPVPERLTRFLTAGSPDELRHRGTAATLTLIDDLLDLGCAGFHLY
TFNRPDAALTILEHLRVRDAAREYRGRSPAA
>A0A7Y4LWS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium australiense|TrEMBL
MTEVTPAAFDGHRALHSPKISFEFFPPKTEEMERSLWETINRLAPLMPNFVSVTYGAGGS
TRERTHSTIARILKETRLTPAAHLTCVGAPKGEIDDVVARYHEIGVRHIVALRGDPTTGI
GTAYHAHPDGYQSSPDLIAGIKKRYPDIEISVSAYPEKHPESPTIDADIDTLQAKVDAGA
ARAITQVFFDNDLYFRYLDRVRARRIDIPIVPGIMPMHNFKQARGFVTRAGTTVPDWLAE
KFAGLDDDAETRKLVAAAVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A6I4T5Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altericroceibacterium endophyticum|TrEMBL
MSYAAIHPDWEKPASNMVDGYSLEMTAKEMDHLREAAPLIRPNTPIAVTFLPGEEMEDRI
AATKLVRELGFEPMPHLSARRLESAEVLENLLKRVTEEAGVKRVFMIAGDPPEPEGPYED
TMQIIESGLLEKYGIEAAGIGGHPEGHPNVSKADLWVWMERKIAALRERGITPLIVTQFA
FDDEAILNWIKEMRERGIDAPVRIGVPGPAGIKRLIGFAKRCGVGASANVMKKYGVSLTN
LIGKAGPDKLIDSLEQGLTPEHGRVRLHFYPFGSLKASADWINEYHAKHS
>A0A1W1WLZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfobacillus thermosulfidooxidans (strain DSM 9293 / VKM B-1269 / AT-1)|TrEMBL
MKTLSQVLQDEGWILGDGAVGTALMDEGVESIALPLVPLRQPDVLMNLHLKYLEAGARLI
ETHTFSANGHKLAALGIDADVVELNRRAAQIARHARDIFGGEAWILGVVGPLAQPVDSQV
MPSVPYEQALEYYRPVVAGLLAGGVDGFIVETMSDLPTVRAAVEAIRSETNLPIAVSFAF
SPQGTTRYGLSPEEAIEAMASLPGGLPALVGANCGSGPAPLLDAIIRMAPKAKELGIPLA
AYPNAGQPGLVAGHVHYPATPRYVATIASALREAGCHVIGGCCGTTAEHIRALQLTLSHA
PEPQVLPSVRDITDASASLDVSHSETHDQGISQFFYKRFIISVELDPPRGVNPHRLLDSA
RVVAEHGADCINIGDSPMARVRLSALATARLISEHLPVQTILHFTTRDRNLMGLQSDLLG
AHALGIRNVLALTGDPPGLGDYAHATAVYDINSIGLVKVLNAFNAGQDALGQKIGGHTAF
DIGVGVNPNADDLNHELQRFREKLDAGAHFVMSQPIYQPEQLERFLDKMGGLPVPLLLGV
MPLVSYRQAVYLHNEVPGIIIGQNILEQFENIQDGTALGIDLALKLMEQLMPLIQGVYLV
PSFNRVEPLLPIIEYLRRQDPWQAKVQGEH
>D0RY39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus RUH2202|TrEMBL
MISTLPMSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAP
LEASKSYPDSIDKVLHFSGKARDIQDFEQFLEQAKAANIQNLLLLTGDKLKEHHNGRDGQ
LRSRYLESVNAVMAAKQHGGFRIGVTFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLG
YDIEALKQAKSFLTKHRYSPQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQ
AGHTDRVYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLKLEALEELWN
SLWQVTTGKEFSPEITRFSRQPSSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWE
NALVAKVLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEF
GDRECIHSVKARLAKAVEQTNVLKEKLIPTVPIETRGTSSWKNWYLATEA
>A0A496P268|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MMKVKEYLQNNILIFDGAMGTYYAALMNDMSSNCEAANIDNPKLILDIHKEYIEAGARAI
RTNTFGLDITNLGGDRKRQKELIKAGYEIAVKAAEDKAFVFADIGPIMAGEHNEKVEEYI
NIVSTFLELGANNFIFETHSSDIAMVEVARYIKKECKEAFVMVDYACHADGYTREGYSYK
SLLEKVANSDVIDATGLNCICSASHMYKLLREINIENIPLAAMPNIGYPIVRGNRTYYGG
SKEYFAEQMKQILEIGVRIVGACCGSNPEYIKIIKGIVDTIGQPVKKKIVYTHKKDFSEL
KNVFWDKVNSGKKVIAVELDSPKDFNTEDFVKSSIRLKKAGADIITIADCPIARPRLDSC
MLAAKLKREHSIEAMPHMTCRDRNINATKALLLGVRAENISNVLTVTGDPIPNAERSEVA
AVYQLNSRKLAAYIDSLNKEVLNNSIKVYAALNVNARKFDSELKRAMTKISSGVVGFLTQ
PVLTDEALQNLKTAREKLDAKILGGILPIISDKNALFIQNEVNGINVPEDMIRLYEGKNR
DEAEKLAYDISVDIAKRMSEYVDGYYLITPFTRIDLMLRIINYIKYI
>A0A7U9NF27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MGMLEKALESGKFGVTVEMAPPKGYDFKEQMEAAELLKGKVHGVNVTDMQSACLKASSLG
LCIKLKEAGLEPIIQVTGRDRSRMGIMGDMLSAAAFGIDTMLALTGDHPTVGDCSQSKPV
YDLDSVGILHMLSVMEATGTDCGGNELEGGAPEFYKGAAVTPVYEPLFLQINKLRQKVEA
GARYIQTQGIFDLESFKRFMDEVDKANIKTHIMAGIIPLKAAGMAKYMNENVPGIAVPQD
MIDRLAAAAAEGKAKGVKGLPTQLGIEMAAEMIAKIKEEGLCDGVHIMAIGAEKNVPKIL
EKAGISID
>A0A6G4EES0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNEKNLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKNIIGE
YNYAFELIEKIKANNNFGVSGACYPEGHIECESLRQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLSKTQQKNINVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A222WLT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus kribbensis|TrEMBL
MKPDLRTVLNRELIVGDGAMGTYLYQLGFPVNTSYEELNMTSPDVIADVHSQYLNAGARL
LETNTFSANDYKLARFGLESRVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
LELARNYDQQIDALLSEGVDGILCETFYSLDEMRIALHGVRKYSDIPVICQFAVDQVGRT
QDGFLVAEAFSVLRDEGADILGFNCHSGPQGIMSVMEQLKGPLSVPLSVYPNAGLADYVD
GHYVYGATPEYFGECAASFVDLGTRLIGGCCGTTPDHIAAISKALSGLQPPPLAPREVLL
KESIHVAEQESTVDQGERGNGRYAGKPNIVEMVKERHTVIVELDPPRDLDITRFMQGAHA
LKKAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFD
ALGIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVV
GAAFNPNVKHLGKAVQRLEKKIASGADYIMTQPVYDRELIAAIAEETRHLEVPIFIGIMP
LASGRNAEYLHNEVPGIQLSDEVRARMSGLEGPEGRAMGVSIAKELLDTAMEHFNGIYLM
TPFMFYEMTAELTSYVWQKSGRVQAPLFRL
>A0A3D0JED1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MEKRGILEVMMEDRGALSIREFLKKHRLVADGAMGTYYSTLKREGNLLSELDNDKDPEII
KTIHKNYIEAGANLIRINTFACYPDVLGVDEAESAKLCRNAVKIAKQAVIEAKNNAELLG
KEESPLEVERKEVFIAGDIGPCSVSNENAERDYKANIDIFIEEKLPVIIFETFTEEKEVL
SLAEYVKEKSPETFVIASFCINGNGTTGRGISLEQIVHHCLESKSIDAFGFNCGIGSSNM
YKVLLSANIKSFNKYFYVSPNAGYPEFLNSRMVFINNTSYYIDYMKQIASLGASIIGSCC
GTTPEYTRKISEFVRELPPVELADEYKEKLEVSEILYASNEFDRKLCANKRVIVVELDPP
YYQDDEKMISRAKELMGYDIDMIDIADSPQGKSRVDSVLMSVKLQNMTSIPCMPHITCRD
RNMISVRSTMLGAYVNNIRNMLIVTGDPIPADIRSSATGVFDYNSEKMMQFLNEMNRAYF
SADPIVFGGAINQGRPNVDYEIKRIKKKMEAGARYFMTQPVYSDRDIEVLDRMKKETGAK
ILCGIMPLISYKNAFFVKNEIAGIVVPDEVLAMYSPDMNREEGEEAGRQISKEVIKKAEP
VVDGFYFMLPFNRINLLDGLVDKKKGMEL
>A0A2D0KLI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus stockiae|TrEMBL
MSFFHANHQEALNQNLAELEGQIRVSFEFFPPQTAEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDANREELCNIAHDYWSSGIRHIVALRGD
LPNGSSKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRIPSWMTRMFE
GLDDDPESRSLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A174HZ39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospira pectinoschiza|TrEMBL
MKIRDIIGMEQETLSMEVFPPKKDTDFEMVKEAALQIASLKPSFMSVTYGAGGSTKGNTI
KLASEIQKQYQVPAMAHLTCVCATKESINTALTEMKQAGIENILALRGDIPKDYDGEVFT
EFQHASQLVELIKKTGDFCVGGACYPEVHPDSKNKFDDINGLKEKVKAGCEFLTTQMFFD
NNIFFNFMYRVREAGIHIPIIPGIMPITKRAQVKNAVKLSGCNVPERFKNIIDKYGDTEN
AMKQAGVIYASDQIIDLLANGVKNIHIYSMNKPEIAKGIQDNLKGIIL
>A0A3D5KY36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKISEILKTKQVTISFECFPPKTQAKYASVEAATEKVAALHPDFLSVTYGAGGGTSEYTL
NIAANIRNKYGVDVLPHLTCVSSTKEKVHEMIRKYKEGGFENIMALRGDIPEGGSPVHDY
RYASELIYDIREHGGDFCIGGACYPEGHVECAHKDEDIRHLKEKVDAGCDFLTTQMFFDN
>A0A5K8ALC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina ovata subsp. ovata|TrEMBL
MKSGSNLEKILRAGHFAFTGELGPPRGSNVEAVREKAKPLVGNVDAVNITDNQTAMVRMS
SWAASLIAIEEGLEPNYQMVCRDRNRLAMQADILGASALGIRNMLCLSGDHQQFGDHPQS
KGVFDIDSTQLIGTVKKMRDEAKFLGGADIDGPPKLFIGGAANPFAEPHEWRVHRLAKKV
AAGVDFVQTQCIFNMERMRTWVKEAVDMGLTEKVYILAGVTPMKSIGMARYMQLKVPGMD
VPNEIIKRLQGVDKKKVADEGIKIACEQIEEFKEMKGVAGVHLMAIEWEHKVPEIAERAN
VLPRPVV
>A0A2C9DBV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hartmannibacter diazotrophicus|TrEMBL
MSPTRSHDGLDIGVSFEFFPPKTEKMEETLWASIKRLAPLSPRFVSVTYGAGGSTRERTH
NTVARMLRETPLKPAAHLTCVDASREEVDDVISDYWMIGVRHIVALRGDPANGVGQRYQP
HPEGYASTPELIEGIRKIGDFEVSVSAYPEKHPESPDVVADIELLKRKVDAGATRAITQF
FFDNDVFERYVERVRKAGIDIPIVPGLVPVVNFSQTAQFARRAGASVPAWIVKRFEGLED
DVETRKLVAAAVAAEQAFDLVDRGFRDFHFYTMNRADLVFAICHLLGLRAKPEEVAKATA
AA
>D5USJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / CCUG 35730 / CIP 100753 / JCM 10117 / KCTC 9821 / NBRC 16120 / NCIMB 702349 / NCTC 13040)|TrEMBL
MTDESRTVLDRLDAVRASGRMPFSVEFMPPRDEAGEARLWRAVRTFERMDPAFVSMTYGA
GGSTRDRTVRVTGEIAETTTLLPVAHLTAVNHSIDELRALMGSYADRDVRNVLVLRGDPP
GDPMGKWVRHPKGLKYASEVVELVRELGDFHVGVAAFPEGHHRSPDLDTDVRYFANKLRA
GADYSITQMFFDVDDYLRLRDAVVAADPEQGAKPLIPGIMPITSLKSVSRMAELSNAKIP
DAMRAELAAAAGDGPEENRAAVRAVGIDIATRMGERLIAEGVPALHFCTLNFAKATSEVL
ENLRMLPVSVPTS
>H0SF16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. (strain ORS 375)|TrEMBL
MTDLATAITDGHSAIPRPKISFEFFPPKTEEMDRTLWTSIERLAPLEPSFVSVTYGAGGS
TRERTHATIARILRETALLPAAHLTCVGASRGEIDDVVDRYHEVGVRHIVALRGDPPGGI
GTPYSTHAEGYQSSPELVAGIKKRHPDIEVSVSAYPEKHPESRDFDADIDMLKAKVDAGA
TRAITQVFFDNDVYFRYLDRVRARGIDIPIVPGIMPLHNFKQARGFVSRNGTSVPDWLAE
KFDGLDDDPETRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPKSV
NKVAA
>A0A354D6B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKLSQILGKDKITLSFEVFPPKTEANYEAVKKAALDVAALNPSYMSVTYGAGGSTRANTV
QIASAIQQQYGITAISHLTCVGATKEDIDHTLDSMKEAGIENVLALRGDRPKDFEGEPFT
DFHYASELVEHIKARGDFCVGGACYPEGHVDAHNKKEDITYLKKKVDAGCDYLTTQMFFD
NNIYYNFLYRVREKGITVPIIPGIMPITRASQVKTACTLAGTNMPERFRNLVDCFGDNPK
AMQQAGIAYATDQIIDLIANGIHNIHVYSMNKPEVAAGIQKNLSEIIHD
>A0A414E287|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus bromii|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKN
FTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A5K8AAZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina ovata subsp. ovata|TrEMBL
MSNNGYKSGSNLEKVLKAGHFAFTGECGPPKGANVEHLKEKFEHLRGKVDSVNVTDNQTA
VVRMSSAAASAIMVANGIEPNFQMVCRDRNRLAMMADILGVYSLGVRNMLCLSGDHQKFG
NHPQSKNVYDIDSMQLIAMVKKMRDEGKFLNEEEIDEPPRMFIGAAANPFADPYEFRIYR
LANKIDAGADFIQTQCIYNMPRFRDFMKQAVDMGLTEKAYILAGVTPMKSARMAQYMAKM
VPGMDVPEELIKRLQDAGKGKQAEEGIKFAIEQIEEFKEMEGVAGVHLMAIEWEHKVPEI
AERAGVLPRPQVN
>A0A010RNC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum fioriniae PJ7|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTAMGLSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKNE
YRDTEDSETDDAEDFVWAVDLVKYIRKNYGDYFCIGVAAYPEGHADESHPQGQSFEHDLP
YLVDKVQAGADFIMTQLFFDIKAYENFEKILKEHPSGAFKNIVLLPGLMPIQSYQMIKRT
TKLSHAKIPDNLMARLDAAKGDDEKVKQVGVDILSELVEQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDPKIEDEEAIIDDGPGIPVPVAVAVPAVQLNGLSPVPHPATRTL
SNGRRPSSMGSDPHNRIIVSGSASNPAYETTTAGLMVSEPVNTRANTLAISEGVGAVGRE
ATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSVTQAMRLWGTPKTVQDINNLFIRHIKGQ
LAAIPWSEEELLPESNIIQQELLELNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQ
KAFVELFIPSSDWAGLVARLNEVTDNTICFYAANGAGDFVSSDASGGLVLEGTEASTNAV
TWGVFPGKEIITPTIIEEVSFRAWAEEAFKIWGEWAKVYGKGSESEALLERIGSEYWLVN
IIHHDYVERDALWKLLSGEKET
>C9S7I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136)|TrEMBL
MHIKEMLADAERDGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIA
ELTCEMVTQAQSVYGLETCMHLTCTDMGLEKVNDALRKGYKAGCTNILALRGDPPREKEK
WVAADGGFEYARDLVKHIRATYHDHFDIGVAGYPEAAMTTRTRSLCSTTSRRRLTWVPPL
L
>A0A7Z8RQE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AY18-3|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6M1SS89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia aurantiaca|TrEMBL
MLDDNFRASRQTADQRPELQLSFEFFPPKTDAMEERFWDSIGKLAPLGPRFVSVTYGAGG
STRERTLRMVKGITADSGVPAAAHLTCVGASRDEVDAVVRGYQEAGVNRIVALRGDPPEG
VGHPFTPHPDGYKNAADLVAGIRKIGDFDISVAAYPEKHPQSPDWDSDIDNLKRKLDAGA
DRAITQMFFSNGDYLRYVERARKAGVTAPIVPGIQPIHSFKQISGFAARCGASIPDWLAE
RFEGLDDEPETHSLVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRP
>A0A3F3H2D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructobacillus tropaeoli|TrEMBL
MKLVDLFEKKTVFSLEVFPPRKNTSKESILPTLSSLNDVSPDFISVTLGAGGTAQGNETI
EVANLIQNQLHVPAVAHIPSLYRSQQQVDELLDQLAADNIQNVLALRGDPVDGLSPNGTF
HHASDLVAYIDREYPNFDVAAACYPEVHQESPSVVADIEGLRRKVDAGADHLISQLFFDN
QHFYEFQERLALAGIQVPVEAGIMPCTNKKQIERITKFSGVPVPKKYQKMLDRYADNPLA
LKDAGIAYAIEQIVDLVSQGVDGIHLYTMNKPEIAEKIWAATKTIFAANQTKDSVEIELV
H
>A0A844CTC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius bejariae|TrEMBL
MTTPSISFEFFPPKSLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRELTREAVGTLHK
SSGLNVAAHLTCVEATRAETLEIADSFAAAGVSEIVALRGDPPKGAGRFTPHPDGFDDSC
ELIEALAETGKFNIRVGAYPEKHPDAANAQADVDWLKRKLDAGASEAITQFFFEPETFFR
FRDACEKAGIDAPIIPGVLPIENWAGVRKFAQACGTQIPAWLDDAFAKAKRDGREDLLAT
ALATELCSELIEGGVEDLHFYTLNRPELTRDVCHALGVTPKVTLRDVA
>A0A6N9SL93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrovum sp|TrEMBL
MNGVVTPRVFSFEFFPPKTPEGVEKLRHTQRQLAQLNPAFFSVTYGAGGTTQDRTLETVV
DIQREGHAAAPHLSCIGATRESLRRVLEQYRSHGIRHLVALRGDLPSGTLGGGEFRYARD
LVRFVREETGDHFYIEVAAYPEVHPQARSAQEGIRHFREKAEAGANAAITQYFYNPDAYF
SFVDDCRAAGIEIPIVPGVMPIANFSQLSRFSEACGAEIPRWIRQKMQGYGDDSAAIKAF
GLEVVTQLCDQLLTGGAPGLHFYTMNNAGLTSVIWERLHLS
>A0A455SY97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermogemmatispora argillosa|TrEMBL
MEHVLLERLRQGPLLCDGAMGTLLYARGVPYEQCFDLLNVTRPELIQGIHREYISAGAQV
IETNTFGANRLRLAAYNLEDRVREINFQGVRRAIEAREIAGLPVFIAGAVGPSGQPLQAP
ETGRLSEVRAAFREQIEALQEGGAELLILETFTSLAELRQAILAAQDVGGLPIVAQVSFY
EDGRTLSGQSAASVARELYELGVDVMGANCCVGPAMTLEALQEMIAALDEEIQSATQQGK
RPPLFSAQPNAGLPTRIGNRFFYVSTPDYFADYALRFAQAGVRLIGGCCGTTPRHIEAMR
KALDTHYGRGREAAGQSGEAGQQNGIAGPAQGQQGSRAAPAPLQVRSGPRPPIGTLPEEE
VILPQEGSKTRLQQKLEAGEFVISVELDPPMGLNPSKILAGAAQLQRDGVDCINIADSPL
ARVRMSCIALARLIQDHLGIETIIHFTTRDRNLMALQAELLGAHALGLRNILALTGDPLR
VGDYPNTTGVWDVDSVGLIRILRGMNEGHDAAGGSIGAKASFHIGAALNLNVSEEEAERE
IEKYYRKLEAGAHFIMTQPIYELAPLERFLQRVGKPPVPIILGCIPLHSWRHAEFLHNEV
AGVTIPERVRERMRAAGDQGTEEGLRLAQELLMEARDLVQGVYLLPSYRRYDIVGRLTRM
LRETPASA
>A0A7I8CE39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. PGU19|TrEMBL
MNPIELSFEFFPPKTQEGLDKLRATRAELLPLKPKFVSVTFGAGGSTQQGTLDTVLDIAK
DGLEAAPHLSCIGSSRESLRAILNEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFRIEVAGYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DAYKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VADLCRRLVDAKVPGLHFYTLNGAAATKAICERLAG
>A0A383R7A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus alvei|TrEMBL
MRDRMKNFREALHEQIIIGDGAMGTYLYQLGYPVGISYEILNVTDPDVIRNIHKQYVDAG
SGLLETNTFTANREKLYRHGKEHLVKDINRAAVRLAREAAGNQAYVIGALGSIRAGKREN
VHTNQVIRDYHEQMSAMLEEGVDGIMFETFYDLEEMRLALQVVRELDQDVPVICQFAVEE
SRRTKDGKSLLEAFRVLRDDGADVVGLNCHMGPNGVLRALEGVQGRIDLPLSAFPNAGLP
DYVDGRYNFVASAEYMAQSAVKFVQMGARIVGGCCGTTPEHVAAIVEALRDVEVPELPVQ
PVESIIIEEESESMLWHDGAACYDGCDHGHDAEESIVDMVRSRHTVIVELDPPRDLDVSK
FMKGAQVLKEAGVDALTLADNSLAVTRMSNLALGYMALDKVGIRPLVHIACRDRNLIGTQ
SHMMGLHALGIDHVLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNSGLAFSGKPLK
QKAKFVVGGAFNPNVKHLDKAIARLERKIEAGADYIMTQPVYDKELIVRIAEATKHLNVP
VFIGIMPLASGRNAEYLHNEVPGIQLSDEVRSRMSGLEGEAGRKEGVAIAKELLDVALTH
FKGIYFMTPFMFYEMTAELTQYVWEKAERQADPLYRLT
>A0A836SPR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Stahlbacteria bacterium|TrEMBL
MFRNKIEKGDFVITCEVLTPLDLNFDNLIGSLTPLRGKIDSFNLPFCPLGRLRPHSLLTA
QVIMEHLKINPILHLAARHQTTLGFEATLLFCQAVGIENILCITGDAPTEGEGNYCLNSI
DLLNLASHLNKGISFSHQQLPVATDFLVCAAYNPNRINIRAENLRLKRKVENGAKVFFTQ
PVFNTKLFLERITEAKEYNPGIKIIAGLSFLYKKKIALRLQKFLGIPYKYIEALGEEDEA
GLLLKTAQAIRNAVDGFYIIPIGHYDQAERLISRFEKNGIA
>A0A6F8W2J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio alginolyticus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSAKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKATTGLVAAPHLTCIDATREELINIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRAVVGA
>A0A3N1VCP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 2132.2|TrEMBL
MSARPTPYPERPAQAPVTGGGLAELLRRVRYEVLPAKATEDKVLAHVPADVPVTVTASPA
KGIGPTLDLATRLAGHGYRVVPHLPARQIADAGHLSDIVDRLVAAGIEDVFVPAGDADPP
AGAYDAALPVLRRLGELGSPFAHVGITGYPESHPLIADEVAVRAMSDKQPHATYIVSNLC
FDPATLRQWLGQVRRRRIVLPVHVGVAGPVERAKLLSMATKIGVGESAKFLTRHPSWFLR
FAAPGGYSPERLLRRAAPALGAPESAVAGLHLFTFNQIAETERWRRAMLERTGG
>A0A1X4NF39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira sp. MCCC 1A01428|TrEMBL
MRVSFEFFPPKTEKMEETMWRSIHRLAPLAPSFVSVTYGAGGSTRDRTHASVTRIQRETG
IPAAAHLTCVGHTRDEIERIAHTYWNEGIRSIVALRGDLPDAGDTYVPTPGGYDYAVDLV
AGLKKIEDFDISVSAYPETHPDAPNADFEIDYLKRKFDAGADRAITQFFFDNDVFLRFRD
KCDKAGITAPIVPGILPVTNFGALLKFAGMCGANVPQRLHHSFDGLDEDPDTRRMVAFHE
SISQVQGLMAEGVTDFHFYTLNRAELTYAICHALGIRATPVAAIA
>A0A525I2D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp|TrEMBL
MADDPLRLSRSGSPVGVSFEFSPPKTPEMETQLWEAIDRLAPLEPRFVSVTYGAGGSTRE
RTHATVSRLVKETRLKPAAHLTCVGASKAEIGAVVRGYSDTGVRHIVALRGDPPGGIDMP
YVAPPDGYQTTESLVAAIKASGDFQVSVSAWPEKHPQSPNLRHDIDALKRKIDAGADRAI
TQFFFDNDVYFRFLDVAAAAGISIPILPGIVPVLNFKQIANFARKAGASVPSWLADRFAG
LEDDPATRKLVAAAVCAEQVLDLIDRGVDHLHFYTMNRADLVFAICHLIGLRAKPALAEA
ATASA
>A0A395RBR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopseudomonas gallaeciensis|TrEMBL
MNKTVPVNFEFFPPKTEAGQAKLIAVANVLAGEQPEFFSVTYGAGGSTRDGTRRTVLQLN
NDVGVPAAPHLSCVGDSREDLRTLLNDYRDCGIQRIVALRGDLPSGMGHASGELRYANEL
VEFIRAETGDHFKLEVAAYPESHPQAPSFEADLKNFIRKAQAGADSAITQYFFNADCYFH
FVDRVRKAGVDIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLESYGDDSDSIKAFG
TEVISQLCERLVEGGAPGLHFYTLNQAEPTVAVLRNLRG
>A0A160UFN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp|TrEMBL
MTDVTTPAHTDGQDGHLKRPAISFEFFPPKTEDMERNLWDTINRLAPLDPKFVSVTYGAG
GSTRERTHSTISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTAYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPDARDFDDDIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARAFVTRAGTSVPDWF
AAKFEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A2G2KYX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastopirellula sp|TrEMBL
MKLADYYTDNKLGVSFELFPPKTEKGDKALHSNVEKLMEFSPNYITCTYGAGGSTRTKTL
DIVSAVKATHGVPVASHLTCVGSSVDELRGYLTEAIDRGIDYIVALRGDPPQGETNFVPD
PNGLRYANELVDLIQAEFSQLGIAVAGYPETHLEAPNADIDLENLKRKVDAGADVIMTQL
FFDNADYYNFRERCEKAGIQIPIVPGIFPVASLPQIKRIANMCGAKVPQSLLDELSQKPE
DAVWHSEVGVQHASRQVEDLISNGVPGLHFYVLNKSEATISIMKNAGLAKV
>A0A2E5GBS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTEHFXQAKETLFSFEILPPLKGKSINSLYENLKPLMEFXPPFIDVTYHXEEYIYKKQ
NNGLLERKAVRKRPGTVGICSAIMNKFQIDTVPXIICGGFNKEETENALIDLDFLGIDNV
LVLRGDPIKSETYFSPENXGHKYAXDLINQVCSMNKGKYLDEDIKNTHSTNFCVGVAGYP
EKHFESPNMNSDIXFLKKKVELGAEYIVTQMFFDNQKYFDFVKLCXDNNINVPIVPGLKP
ISIKKHLNLLPHRFHLNLPEXLVKNILKCKNNXDIRKVGVEWAINQTKELIDYGVPCVXY
YTMGNSSNIIDIVSKFN
>A0A4Y9SZD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia horti|TrEMBL
METHNFSIEFFPPKTPEGAEKLRATRRQLAELRPKYFSVTFGAGGSTQQGTLDTVLEIQS
EGHPAAPHLSCVGGSRESVRAILQQFQAHGIRRLVALRGDLPSGYGGAGEFRYANELVEF
IRAETGDWFHIEVAAYPEMHPQARSPQDDLQNFARKVKAGANAAITQYFYNADSYFQFVD
GVRKLGVDVPIVAGIMPITNYTQLMRFSEMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQAVATTAIWQRLVSR
>A0A350M6J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTDKIKESKSPLLSFEILPPLKGKSIQSIYDSIDPLMEFKPAFVNVTYHREEYVYKKR
EKGFLEKVSIRKRPGTVGICAALINKYDVEAVPHLICGGFTREETENALIDLYFLGIKNV
LALRGDPIKTEQHFVPEEGGNNYAIDLVRQINNLNKGIYNDEDMINAMPTDFSIGVAGYP
EKHFEAPNIETDLMHLKRKIDAGAEYIVTQLFYDNKKFFDFVKLCRGAGIDVPIIPGIKP
ITRKSQISLLSKFFHVSLPYDLSKELDAARNESEVADLGVKWAADQCRELLQEGVPCLHF
YTMGKSSAAKRVVEQIF
>A0A1W6YSG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella genomosp. 8|TrEMBL
MTDTTTPAYSLEFFPPRDIAAQERLLRAAKQMLAIHPRYVSVTFGAGGSTREGTAGTVRT
LRNLGVDAAPHLSCVGATLADLRAILASYREEGVRQVVALRGDLPSGMGGDAGELKYARD
LVAFIRKETGDWFHIEVAAYPEMHPQADNPSRDLDHFVDKVRAGADSAITQYFFNPDAYF
DFIERVAAKGVSVPIVPGIMPITNHTQLARFSQMCGAEIPRWIRLRLAEFGDDKASIRSF
GVDVVTDLCRKLLDGGAPGLHFYTLNSAEAPLAIWKNLTSKV
>A0A7W2PWF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mosselii|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYQTAGIRRIVALRGDLPSGMGMASGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0W8E308|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrocarbon metagenome|TrEMBL
MKIIEFYKLSEKPVLSLEIFPPHTSYPVESLFETVEELRDLEPDFISVTYGAGGSTRDRT
VEIASSIKSDFGIETLAHLTCMAHSKQEVDHILETLWDRGIRNIMALRGDPPADLENLDL
LKREYHYARELIEEARKKADFGIAAAAYPEGHPECQKLSDDIIHLKQKVDAGVDVLISQL
FFDNRKFYDFIDRSLQIGINCPIVPGIMPVLNAKQIQRMITLSGASVPSDLLKLLDRYDD
RPEEMEKAGIEYASRQVEDLLTNRVAGIHMYTMNKSKQIKEIVKNAGL
>A0A840SJB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema rectale|TrEMBL
MKISEILQKKKITLSFEIFPPKQQANFNNVVNTAVNLSSLNPDFMSITYGAGGTTRGNTV
EIAQKILESGTPALAHLTCVGNTEESIKSDIQKMKTAGIQNILALRGDVPQGQTIESATT
ESLRHADQLVTILKKEGFCVGGACYPEGHPESANRADDIENLKYKVDAGVDFLTTQMFFD
NNMLYSYLYRLQSKGIHLPVFAGIMPIVNSNQVERMVKLSSAYIPEKLLSICDRFADNAP
AMRQAGIAYATDQIIDLISNGIRGIHIYAMNKVDVVTDIVKNIDRIMEAVND
>A0A2M8MGK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDVAPLEASKSYPDSIDKVLHFSGK
ARDIEDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKNNYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYVEQYRHLELEALEELWNSFWQVTTGKEFSPEIRHFSR
QPTSKQLIKYRQLHLMHEAMFGSKIAKGLGRFIFKASFWENALIAKLLLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVEQT
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A1Y3F6S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHHYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGYAGIHLSACHKPEEQMLLESYVEQYKHLELKALEELWNSLWQVT
SGKEFSPEIRHFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGIGRFIFKASFWDNTLVAK
VLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKEKLIPTVPLETRGTSSWKNWYLNVEA
>A0A7K3DS37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5785|TrEMBL
MALGTASTRTDRARTVRDMLAPGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHITAVEHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVSHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSADWDSDVRHFVD
KCRAGADYAITQMFFHAEEYLRLRDRVVAAGCDTPIIPECMPVTSVRMLERLPKLSNADF
PQALKERILTAKDDPAAVRSIGIEFATEFCAKLLDEGVPGLHFITLNNSTATLEIYENLG
LHDQRA
>A0A2S4LQS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. V23|TrEMBL
MPTASQHRASRDSYRPIRVSIEFFPPKTDEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMIKETSLQPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPQDGVG
TAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEAPTLDADIDALKAKVDAGADQ
AITQFFFENDIYLRYVDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLDNDVDTRRLVAAAVAAEQVLDLVDHGVNDFHFYSMNRSDLVYAICHVLGLRAQAPKV
AAKAA
>E8TIA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium ciceri biovar biserrulae (strain HAMBI 2942 / LMG 23838 / WSM1271)|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>G5S3R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Urbana str. R8-2977|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A438N3S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala mesophila|TrEMBL
MDDDRLPTLLSSLPPSSQYFSLEFFPPKTSSGFSNLQSRLARMTAALRPLFVTVTWGAGG
STATKSLELAEICQRQLGITTVLHLTCTNMKRTAIDEALESAKEVGIRNILALRGDPPRQ
EYRDTDENGSGGAGTDSNQEFAQAVDLVRHIRSRYGDYFSVGVAGYPEGHADESNPERGK
QSVDNDLPYLEDKVAAGADFIMTQLTYDVVAYQAYETRLRHHVTKDGRKLFANIPIIPGL
MPIQSYQIIKRITKLSHARIPDAIFQRIEQVKTDDEAVKKVGVQVLSEIVEQIKELPQPD
GIPRGFHFYTLNLEKSVAFILENTNLIPTISDSSPIDSSDSEALVDDDKVRNYTSARLPS
GQNGNVAHFSKRRASSMNAQPHNRVITDDLPHQNGHSRPTTDSRPLLSQHEAAGRGSGIP
ASIPTRKDNLLISEGQGSLGREATWDDFPNGRWGPSHSPAFGEIDGYGPSLKVGPITARK
LWGHPKSSQDVTSLFRRVVTGDLEAVPWSDEVDVDGAGTGSGALRAETKVIQQDLLALIE
RKGYWTLASQPAVDGAKSEDETFGWGPPGEGFVFQKAFVEFFCSQEEWNQRLRPLLLKHG
EDKLGWMKTDAQGIFESSDEEFHRHSVDRPSSKRNPGVHGVSAVTWGVFRGKEIISPTII
ESESFKAWGEEAFSIWKAEAEAVDAVLDDDSEGGDCARRNDLNP
>A0A0V1H1P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella zimbabwensis|TrEMBL
LMASLDAVELKTTRHDLNSSPKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTPEGL
INLLNRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCVLNFCLLDTMLHITSVQY
NEKTVLSNLERVKKIGIRNILALRGDISDDANVTATDFQYACQLVQFIRSHYGDYFTICV
AEDLLNLKAKVDAGADFIITQLFFNEMHYFQFVSDCRKIGIVVPIIPGILPIQSYQSIMK
IVQLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVELCRKLLNAEQHVVPGLHFYTLNQ
EKSILEQIGLWKKAPGRILPWKKHPVHSVRCREAVRPIYWNARPKSYLCRTRDWKQFPHS
RWGDLGNPAFGDLKHYLFSCIDQMNDSRALDMWDKELSSFKHVRDIFCNFIARTPNRHGH
TVRRLPWNENHLDPAVDILKDELIYYNSNGILTINCQAAVNGLPSNDPTFGWGEANGYIY
QKGYLEFFASSKCTTILLNHVQNFPSVNYHAINFDGSFETLNYDEDATMALTWGVFVGQE
ILQPIVANAASFRVWKDEAFDLWQRWARLYESGSIGRKLLQSIHDDHRLITLIDNDYPQP
CSLSALLRAVISEYCEEKN
>A0A418KT47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiangella rhizosphaerae|TrEMBL
MALGLPSTMPGGARTIRELLAAGGRSFSFEFFPPKTEQGEAAFWQTMRELERLQPTFVSV
TYGAGGTTRDKTVRITEGIARDTTLTVVGHLTAVNHSVAELRNVIGQYADAGVRNFLGLR
GDPPEGPHGEWVKHPEGLEYAEELVRLIRAHGDFCVGVAAFPDKHPRSPDLDTDARFLAR
KFQAGADYAITQMFFHADDYLRLRDRVAAAGGEAPIIPGIMPVTNVRQIQRFAVLTDAAF
PAPLAQRLLAVEDDPEAVRAVGVEVATELCERLLAEGVPGLHFYTLNKSTATREVYQNLG
VGALS
>A0A2U1XRU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. TSH64|TrEMBL
MTAPTSALPSISFEFFPPKSEKMEQSLWQSIRRLAPLSPSFVSVTYGAGGSTRERTHATV
CRIQDETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGIGGQYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDAYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPAKLAETFEGLDD
DPETRQLVAATVAAEQCQALQAQGVNDFHFYTLNRSDLTIAICRMLGVKAKAAPAAAAVA
G
>K9ABW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WC-141|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLRIVHQELQLLNPDFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A2H6IRY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Bbin09|TrEMBL
MSFRDIVESGKFVVTGEIGPPKGTDIKEVLHHIELLKGKIDVANVTDNQAAVMRISSLAG
CQLCLQNGLEPVLQMTCRDRNRIGLQADLLGASVLGIKTVLCLTGDHVNAGDHKQAKSVY
DVESVQLLKIVNGMNNGFDMSGNELQGATDFYPGAVVTPESVPLEPQLVKFEKKVEAGAK
FFQTQAIYNMDKFKDFMKYARQFPVKILAGIVVLKSAGMANFMNKNVPGIMVPQDLIDEM
KAAGKEKALDTGLNIAARHIRQLKEEKICDGVHIMAIGMEDKVPEIMERAGLL
>A0A838ZYZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deefgea sp. CFH1-16|TrEMBL
MTNPLRPISFEFFPPKTDEGAAKLATTRRQLAQFNPEFFSVTFGAGGTTQEGTLRAVVDI
QAAGHAAAPHLSCIGSTKDNIRQVVQQYKNHGIKHIVALRGDIPSGMGEFGEFRYANELV
SFLRSEFGDWFHIEVAAYPEFHPQSPSAEADLRHFINKVNAGADSAITQYFFNADAYFRF
VDEVQARGVSIPIVPGIMPIQNYSQLQRFSDMCGAEIPRWLRLRLQAYSDDTASIRAFGL
DFVTELSDRLLAGGAPGLHFYTLNAAGAVSTVCQRLGY
>A0A7C4GGA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium thailandense|TrEMBL
MSLGCELLRKRFILETLPPRGSNYEKYVDFCLGAVDNGAQVIAVTDLPMGSSRVSPIAPA
HILVEKGVEVLMHFSRTTRNALRIEGDLIAAHMLGIKNLLILSGDDPRVGTYPFASYIED
FSIYDVFKLTELMNRNNENLAGVRLYGKFDFCCGGVFSPYEKDIAGTVNRMRGKFDNGCA
FFISQPVFLPEVMETFFTKAQELDEEMFSKAKIYVALMIFETVSQMEYFSKVPGVYVPRE
YFHPRKDEDLKRYSLNKALHVVESLRAYVHGFYLTATVRDFEIIRLMAEAIL
>A0A7X5XZ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas trueperi|TrEMBL
MSIVDPMAPPLFADVAGDVAVSFEFFPPKTEKMEETLWASIETLSPLGPRFVSVTYGAGG
TTRERTHATVSKIARETPLAAAAHLTCVEATREEIDQIAEEYWAAGVRHIVALRGDPPRA
GEKYRTHPGGYENAADLVAGLRRLHPFEISVSAYPECHPDSPSPEADLDNLKRKIDAGAN
RAITQFFFEAETFLRFRDRAAAAGIDAEIVPGIMPVMNYASVVKMSAMCGTDVPAWMEKL
FEGLDEHPGARQLVAATLAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGLRPRQQA
AVAAA
>A0A7Z6T6I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CBMAI 2042|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCATLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A8H6IE69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tulosesus angulatus|TrEMBL
MKLSEKINARGGSRPFYTFEFFPPRTNQGFENLVARISRLATLDPLAISVTWGAGGSTKD
RSLELAGITQSHPYSLATMLHLTCTNMQEGLIDDVLESVKDRGIQNILALRGDPPRGKEE
WIPSDPRFTHAIDLVRYIRSVPEYSSHFCIGVAGYPDGHPDSPLSEDAEIDNLKAKVDAG
ADFIITQLFYDVDQFLRWVKKVRAKGITVPIIPGIMPVQTYATFARLTKLCGTKVPKKLE
DELTPLKHDDRLVKDYGVNYAIEMIRKIHSDGDIQGFHFCTLNLEKSVQRVLEGLQWTGA
VNEVSNKLIADIPAPLTENSQGTEFLITPSSAANNATSGLVSFSKTKTKNEMGKGEVNDA
ASWDDFPNGRFGDFKSPAFGNQDPWGGSGMTRTDIHPQWANPKSSEDLTRMFMSYLESKI
TTTPFSDGALCPESVTILPQLKKLTQRGWWTVGSQPAVDGISSADETFGWGPRSGWVFQK
AFVEFFCDGKDADAIEAYIAEKGQGWVHYFMANGKGDFRGNVAGDGRNAVTWGIFPGSEI
LQSTIIERESFITWKEEAFSIWKSWASFYRPASPERQLLDEVAKERWLVSIIHHDYKNAD
ALWTFLFDSELGF
>A0A1P8M8T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. QXT-31|TrEMBL
MRFNHLPVRLEIIPTDGIIRDVQAHVPAGSTLTVTCLPHHGPEATVRAAVQLGGLGYNVI
PHLAARGLSSRTQLAGLLRECEAAGITEVFAIGGDAVEAAGPYGNSLRLMEDIAELTGGS
MAIGVAGYPEGHPKRNELDMLDALLEKQHLASSVVTQMCFSATRIGWYAELLRREGVGLP
IWAGVAGAVPKAKLISLATKIGVGPSLKFLNRKGPLARRLLNAGSYSSTSLVSELAATEP
ALAGIHLYTFNNVEAQPATDWSTPAGANAS
>A0A349HM19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp|TrEMBL
MKIIDLINKNEQFISLEFFPPKDRDSWPKFFEVVGKLKVLNPLFASVTYGAGGGTQDNSL
EIVKRMKQDAGVEPLAHLTCVGASPENISEFVSALQEAEVENILALRGDAPADEKDFDFN
TQPFKHGSDLVTYVKDKHPGVGVAVAGYPEAHLESPSIKEDFKWMKYKIDEGGEFIITQL
FFDNRVYFDFCDRLKAMGIEVPVVPGVLPIMSLKSAKFILSLCGAAIPGKFLSTLEKAHA
EGGDDAVYKLGIEFATKQAQELLDGGAPGVHLYTLNRAKACLEIGQALKF
>A0A3D4GH80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp|TrEMBL
LDVAAVLEGADALARAGVDAITLAENPLAAPRLSNIALAQRIRARSDIEVIVHLTGRDRN
LIGMQSTIMGLACLGLENVLAVTGDPPSTGGEERLSGVFDVRSFELIALLENFRQGRNAH
GQDMRAAANFCIGAAFNPNTRNIAMQVKRLSRKAALGARYFLTQPVYAKEKVDEVIAAVK
DVAQPIFLGIMPLVSLRNAEFLHNEFPGITIPEPVFARLREAGDGQAQEGLEIAWELMEY
ALPHFAGMYVIPPFNRYPLALELIKRARTAFPQSR
>A0A357AXH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp|TrEMBL
MQIAQLIAASRSPFLSLEFFPPKDRGTWPGFFEEVGKLKALNPLFVSVTYGAGGGTQANT
LDVVTRLKRDLGLEPMAHLTCVGASASALHGFLKELVAAEIHNVLALRGDPPKDRPDFRF
EGQEFQHASDLVAFIRREYPGLGVGVAGIPTKHPESATLEDDLRWLKFKVDAGGDFVVTQ
LFYDNAHYFEYVRRLRGLGLTVPVLPGILPIMSMKSAQFISGLNGRAVFGGFYEVLEQAF
ARGGDEAVRELGLAHATRQAQDLIDRGVPGVHLYTLNRAEACLEIAGNLKL
>A0A1B9LCT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNQKTVFSFEVFPPKKTSPLATIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVPPKDDF
RFASELVTFIKENGDFNVIGACYPEGHLEASTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKAHDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVATLLAVPKSK
>A0A1I7I4V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. DSM 8431|TrEMBL
MKIKEIFDRKKTVFSFEIFPPKTTSSIETIYKTLDELTGLNPDYISVTYGAGGSVQDNKT
IELSSLVKNKYNIESVAHLTCINSTKADIDCYLKSLKENNIENILALRGDIPRSGEVKGE
FSYASDLIDYIDNTEFNMAAACYPEGHLERKGLVNEVLNMKRKQDAGASYFISQLFFDNE
AFYRFKEEADRTGIVIPIEAGIMPVTNKKQIERMISMSGATLPKKFMKIMDRYEHDAEAL
RDAGIAYSVEQIVDLISSGVDGIHLYVMNNSYLANKITGSIKNILNSENRL
>A0A1F8RAQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_60_22|TrEMBL
MANSSFEEKLGSNKFVVTTEVGPPKSVDISEMVHHIELLKDKVDAINITDHQSSVMRFPS
LGGALLVKELGGEPVLQMTCRDRNRLALQADLLMAYSRGITNVLCLTGDSVDVGDHKEAK
PVFDLDSVQLLKMIRTLESGTDMGGNELKAAPRFCIGATVHPEADFVEPQLVKFDKKVAA
GAQFFQTQGIFDLASLRRFMQYASQFNVKILAGIIVLSSAGMARYMNNNVPGIIVSQTII
DELAAVEKGKGLQKGIEIAARMIKTIKEEKLCHGVHIMAVGNERVVPGILEAAELVNA
>A0A242NLL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNQKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKNEMKKILHDLKCAGIDNVLALRGDINPNVKPKDDF
RFASELVSFIKENGDFNVIGACYPEGHLEATTIKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKARDMDINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKSK
>A0A212JU51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Dysgonomonas sp|TrEMBL
MTVSELINKNDKTAFSFEILPPLKGNNIEKVYNIIDKLIEFDPQYINITTHHSEYLDQEM
TDGSVKRVNIRKRPGSVAIAASIQHKYNVTAVPHMICKGFSQEETEYALIDLNFLHVHNL
LLLRGDTKRLAPEQIYPNRNEYATDLQVQVNKFNEGIAADGTTFEKNATPFAYGMACYPE
IHEDAPSMESDIHYMKQKADNGAEYFVTQMFFDNEKYFSFVDKCRKAGITQPIIPGVKPI
VLMSQLEVLPRIFRSSIPEELAIELRKCKTDDESKEVGVEWGIKQCKELIAHGVPSLHFY
SLLATESVRRIAKEIY
>A0A1N6DJF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus halophilus|TrEMBL
MKITEHLKKADQTLFSFEILPPLKGQSLKELLEGIAPLMEFKPPFVDVTYHREEYIYKKH
PNGLLEKISTKKRPGTVGICAAIMNRFQVDAVPHLLCGGFNKEETENALIDLNFIGVENV
LALRGDAPKTEGKFIPEPDGHHFASELVEQIVRMNNGKYLHEETETSFHTDFCVGVAGYP
EKHFEAPSMKFDLKRLKEKVEKGAEYIVTQMFFDNQKYFEFVDQVREAGITVPIIPGIKP
ITTVGQITMLPRTFFLDLPDPLMDELEKCKTNAEVREVGIEWAIKQCKELVKAEVPSLHF
YTMSKAGTTYAIAKEIF
>A0A556RHM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNQKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHAVKHTYGIESVAHLPGINFDKAEMLKILHDLKCAGIDNVLALRGDISPNVPPKDDF
RFASELVTFIKENGDFNVIGACYPEGHLEAATLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKAHDMDINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRICEAVSTLLAVPKSA
>A0A5X3R4E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Saintpaul|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7V4WF12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKTESKLEKILTSGALAVTSEVGPPRGAIPEKVRQKATLIKDHVDAINVTDNQTAMVRMS
SWAAGVIIKQMGLDPILQMVVRDRNRLAMQSDIIGAYSMGINTMMCLSGDHVKFGDHPMA
NGVFDLDSIQLVQTVKKMRDEGKFQGGAEIKTPPKMFIGAAANPFADPFELRVMRLAKKV
KAGADFIQTQCIFNLDKFEKYMEMVCDRGLDQQVHLLAGITPMKSAGMARYMKNKVPGMD
VPDEVIKRMAGVSKEEQPEEGIKIAIESIQRLKEVKGVHGFHIMAIEWEEKVPQIVEKAG
LFPRPVL
>A0A4W5N757|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hucho hucho|TrEMBL
MVNNVQRVDDTWRTCTKSDSSGTSSGGESSKESSRSSTPVLDADRMDRLRDKMRRRTESG
DHWFSLEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKDKITGYLSKAKRLGLKNIMALRGDPVGADWEEEEGGFNYAT
DLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADTF
LKFVRDCRAIGITCPILPGIFPIQGYQSLKQLVKLSKLEVPEEIMRVIEPIKDNDAAIRN
YGIEQTVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLKMWGEELTSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLLMDELDKVNR
RGVLTINSQPTINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENITVLLKVLKKYEPRV
NYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPTEQPA
EQPAEESPVEDQPPK
>A0A800CWV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
VVTGELGPPKNGNPEVVREKAQLLKGNVDAVNITDCQTAIVRMSSIAAGLIAKEEGLEPV
IQMTCRDRNRIGMQSDILGASALGLKNLLCLTGDHQKFGNHPGSKGVFDMDSIQMLGMMK
GMRDDKQFQCGEEIKSHEPKMFLGAAANPFAYPFEYRAVRLGKKVAAGADFIQTQIIYNV
EKFTEFMRMVRELGLHEKCYILAGVTPPRSLGMARYMKKFVPGMDVTDEVIQRMKDAKDK
QDEGIQICADIIAQVKDIEGVSGIHCMAIEWESAVPEILSRAGLLPRPGITEAEAPAKAE
ETKEQITVQAVDTDDVLEKAKAEAEQIIAAAKTEAANIMQNAGSQSSVATATTSTTIDAP
QGADDSGEHEMNEKERIMALDSVNLGLAALKKAYGLTDDQFEALASFAGAHAILKKDPDV
DSTATAAPSAPAAAPAAPAAPPVDDSAEKAKAEAEAKAKADAEAKAADEAKAKAAEEAKA
KADAEAKAAADAKAADEAKAKAAAEAKAAEEAKAKAEAEAKAKEEAAAKAPVAAPVVDSG
VAELAKETVSLADRSTKVAPTNYETKYSGTIRTVKMGNEGNEKLVGGSASMPFQLFEGEH
PNKPLIAMEVADVKPDEWPETLSQHFSDVFENPVAWAEKCVKTYGAEAIAITLGSTDPNG
MNRSAADAAKTAADVIAAVDVPVIVWGCGNSDKDTETLRDITSVIGDKKVCLAPLEDANY
RTIGATAMAFQHPIVAASPIDVNLAKQLNILLENLGLSLDTVLMDPSIGALGYGIEYTYS
VMERIRIAALTQQDEKLQVPIICNLGCEVWKAKETKLPSDDMIGDQETRGIMMEAITASC
MLMAGGEVMIMRHPKAIALTKALIAGLMD
>A0A071LPF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mangrovibacter sp. MFB070|TrEMBL
MSFFHANQRDALNQSLAEVQGHINVSFEFFPPRTSEMEQTLWNSIDRLSSLRPKFVSVTY
GANSGERDRTHSIIKDIKERTGLVAAPHLTCIDATRDELKSIAQDYWDNGIRQIVALRGD
LPPGSGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVENYLRFRDRCAAAGIDVEIVPGILPVSNYKQLQKFATMTNVRVPQWMATMFD
GLDDDPETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAI
>A0A3M3RB13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. coronafaciens|TrEMBL
MGSMSQDRRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVL
QLENEVKVPAAPHLSCVGDGKDDLRNLLAQYREAGIKRIVALRGDLPSGMGMASGELRHA
NDLVTFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADS
YFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQ
AFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A351B0Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MHLQEKLEFKKFIILAEMEPPKGTDVSSLVANATNVKGRVDAFVAPEMNNAVMKMSSLGA
ALLLQSKGFETVMQVCCRDRNRLALQADLLAAQALGIPNVMAVTGEDISYGDHHRARAVN
DLDLLELLAAIQTLQSGRDLAGIELQGAPRFLVGASLNVGKSGGALEAELAELDKKMAVG
AQFFITSPIFALKVLDQFRKRLGNRPAKIIPTVMLLKSVGMARYIDRHLEQIHIPAGLIE
RIHKAPDRVRECIMIAAELIAGLKDEGYSGVQISTLGWEDRLPAILAAARA
>A0A257J729|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium PA2|TrEMBL
MSQTRSALGPVARAGAGLAKRPSISFEFSPPKTPEAEESLWEAIRRLEPLNPTFVSVTYG
AGGSTRDRTHRTVVRMLKETTLKPAAHLTCVEASRAEVDEVVQAYWDAGIRHIVALRGDP
PGQIGGAYVPREDGYLNATELTKGIKAIGDFEVSVSLYPQGHPENADLDKDIDVLKAKID
AGATRAITQFFYDTDGFLRFMDRVRKAGVTIPISPGIMPVSNFKGLKKMAAPVGITLPDW
LGNLFEGLDKDPESRKLIAASVAAEMCAGLAEEGYSDFHFYTLNRADLVYALCRVLGVRE
TPTEAA
>A0A4R9WAB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.217.01.1.1|TrEMBL
MEKAAIRPSSIDASIEMAPSQVIDSPDLPGLFPSGVRVYITDIGLADTPTLVKAARRVAD
LGYTAVPHMAARRLTTRQALETRVKALAEEAGVRDLLIIGGDVATPAGSFSSSFEVLQTG
FVDKYGITEVGIAGHPEGSRDFGDEAAIAALRMKSAWAERTGAKMRVVTQFGFDADKFIA
WADGLAVSGVDLPIHLGVAGPAKITTLLKYAALCGVGNSLNFLKKRSASLAALATSHSPE
SFVGPIEHHLRAKPESAIAQLHVFPFGGIKNTARWLYERGSWQGLEADDRSSIA
>A0A1C4UAK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora matsumotoense|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTAQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVR
GDPPGDPGGEWIRHPEGVDYAEDLVRLVREAGDFSVGVAAFPYKHPRSVDVDSDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFDRVADDPEAVRRLGIDQASKMCARLLDEGVPGIHFITLNRSPATREVWRSLR
ADARV
>A0A3S5JTJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium TMED135|TrEMBL
MKVXDYIKNSNKTIFSFEIIPPLKGKGIEDICEGIDPLMEFNPPFINVTYHRXEYDYKKM
GNGLLKKVSVRKRPGTVGICAALMNRYKVDAIPHIICGGFTKEDTESALIDLKFLGVDNI
LALRGDPMKNESAFVPTDGGNKFAIDLIKQINDMNNGQYLYEETKNSPSNFCIGGAGYPE
KHFEAMNLKSDLKHLKEKVDAGMEFIVTQLFYDNKKFFEFEKKCREIGITVPIIPGLKPI
TNLRHLTFIPKFFNTNFPEEFSNELEKCKTNDEVKKVGIEWSTIQSKELVKAGVPVLHFY
TMGKGESVKNIASKIF
>D2Q0D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)|TrEMBL
MVNGLASTRPGSTPTIRELLATGDRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGAGVRNVLALR
GDPPGGPRQPWVAHPDGLNHAVELVELVRSLGDFCVGVAAFPDKHPEASDLDFDARVLAA
KAKAGADYAITQMFFGADDYFQLVDRAAALGCDIPILPGIMPVTNIKQIHRMAELTGMAL
PTAVTDRLHAVEHDPAAVRAVGIEIASELCDQLLAGGAPGIHFITLNRSTATRQVYLNLQ
GTTV
>A0A2E3SFE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda sp|TrEMBL
MKVTEHIKKAKGETLFSFEIIPPVKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYIN
RDGLLDKKLTRMRPGTLGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFEPTKGGHRYASDLVKQIQRLNCGEYLHEVIETDNCADFCVGVAGYP
EKHMEAPSMNSDLKRLKQKVDLGADYVVTQMFFDNQKFFDFVEAARKIGIEVPIIPGIKP
IAIKRHLQLLPQVFRVDIPQDLVDAVEACKNNKEVRQVGIEWCIEQSKELKKAGVPVLHY
YSMGKSDNIKAIAEAVF
>A0A7K5I4L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crotophaga sulcirostris|TrEMBL
MVNETQQTCSTSSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAADL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FVKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYISGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFLLLN
>A0A838KG15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporichthyaceae bacterium|TrEMBL
MPTTLPVTVTASPRWGLEPTLALTEVLARQGFSMVPHLAARLVSSEQHLSEILCRLDEAD
VRDVFVVAGDGATPVGDFADSLQLLTAIERLRQGGFGRKQHSVGITGYPEGHPLICEGDL
ALALHSKQSLSSYVVTQMCFDAEAVGHWIRHVRQLGVRLPVHAGVAGAVDRLKLLRIAGR
IGVGTSLAFLRKQHGGARLLRSGGYRPDQLVEALAAGVGQEGRGISGLHVYTLGDVAATE
RWRRELLDRLTAGGPEHG
>A0A0M2US65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Brocadia fulgida|TrEMBL
MVENSSGIKSGSNLEKLLRSGQFAVTAELGPPRGADRSAIEKKAGILKGYGDAFNITDCQ
TAVVRMSSIAASRIVLDAGLEPIIQMTCRDRNRIAIQSDLLGAAALGAKNLLCLTGDHQK
FGDHPMAKGVFDIDSIQLIHMVKTLRDGKKFQGGQELKASEPKFFIGAAENPFADPFKFR
AIRLAKKIAAGADFIQTQIIYNTKKFKEWMKIVTDMGLHEKTFILAGVAPLKSAGMAKHM
KHNVPGMDVSDEVVNRMTVASAAKKGKEEGMKICLEVIEQVREVKGVAGVHIMAVEWEEA
VPEIVRQAGLYPRPVV
>A0A1C3ZLI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella intestini|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVQPKDDF
RYASELVSFIKESGDFNVIGACYPEGHLEAATLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYTFLDKARDIGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMIEKYEHHPEAF
RDAGIAYAIDQIVDLVSQDVDGIHLYTMNNSYIARRISEAVSTLLAVPKSE
>A0A2D5B9K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHMSEIIQRDGKTFSFEFFPPRTDTAWDALLARMGDFSALKPSFVSVTYGAGGSTRQRTN
DLVVRLKQEGGVDPIPHLTCIKHTRDEIESILERYAEAGISNILTLRGDHPIEDVGYAAT
DDEYQHAIDLVRHIKAFNDSGRHPSPRGFGIGVAGFPEGHPETPNRLKQLEYLKQKVDAG
ADWVTSQMFFDNASFHDWCERCELEGIDVPLIAGIMPITGIRTMRRMADLAGGTNFPAKL
QRRIHRHQDDDDAVRQVGVQWATEQCNELLDHGVAGIHFYTLNQSDATLEIFRGLGANDT
ESLRR
>R8B4W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter lipolyticus SM19|TrEMBL
MKLAYQRQTGKAEDPRTVALVQELVRAASIEATPRQILETDSLAELLPAGTWVYVPFLPH
GQFSETLPACQRLIDAGMQPVPHLPARLVESHDQLRDWLGQLRAIGVDRLMLIAGDSDSV
AGPFPDTLALLESGLLEQQQFLHLGVAGHPDGHPVADQESLRRALSLKRDYARVTGSRLW
VVTQFAFEAERYTGWLQAVGDILPEVPVYMGVAGPTNLKTLITYAAQCGVGVSARTMWRK
PGSARLLRSWTPDGLVHALARHRQDFPDTLLAGIHLFPFGGLQRSARWIRQCGEPDEPEE
ARGSLSDPVSDSV
>A0A7H0LPU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas alpina|TrEMBL
MTISINQLEEARRALDAPLFADVAGDAEVSFEFFPPKTDKMEEALWEAVKTLEPLGPRFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATKEEIDEVAEAYWAAGIRHIVA
LRGDPPVAGSKFVSHPGGYDNAADLVAGLKKLHPFEISVAAYPECHPDSGSVDVDLDNLK
RKLDAGANRGITQFFFSPEAYFRFRDRVAAAGITAEIVPGILPVSNVAQTRKFAAMCNAE
IPDWMGRLFEGLDDHPAARQLVAATVAAEMCRKLYAGGVRSFHFYTLNRAELSFAICHLL
GIRAKTQAKVAAA
>A0A845N374|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp. ZXX171|TrEMBL
MSKRISFEFFPPKTEQGREKLLNTQKKLLVKKPEFFSCTFGAGGSTRDYTRQMVDLLREQ
HADTAPHLSCIGQSRDEIMELVNGYKEKGVTRIVALRGDLPSGMGYAQSEVKYADELVAL
IRAETGDHFNLEVAAYPENHPQSRSFDDDIGHFKRKIDAGADSGITQYFYNADAYGYYMD
ELRRRGCEAPVYPGIMPILNVANLFRFSDNCGADIPRWLRGRLDDIRDDEAAVKAFGEEV
VTRLCERLLAMGAPGLHFYTMNQAAPILRILDNLGL
>A0A8C7VT77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
MVSFGRVEAIFIISPGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTESGDHWFS
LEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSNKETSSMMIASTAVNYCG
LESILHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKH
IRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVR
DCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIRNYGIEQ
TVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVED
VRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMW
GEELTSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDELLAPETNLMMDELDKVNRRGVLT
INSQPTINGKPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPRVNYHIV
NVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYED
ESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPTDPAK
>C2ZCV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus AH1272|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTLKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKSHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A3C0TLF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MKSGSTLEKVIASGKPAVTAELGPPMSADGHEVEKKAQLLKGHCDAANITDCQTAVVRIS
SIAAAAIALREGLEPVMQMTCRDRNRIAMQADLLGAAALGLKNCLCLAGDHQNFSAAGRL
KGHAGAKNVYDVDTCQLVGILKKMRDEGLQEGGDPLEVAPKYFIGASWTPMADPIDFRPV
NLMKKVNAGADFIQTQGIYDIEGFRSQMKKIVNMGLHERTAILGGIIVPRSGMMLKYMDA
SVAGVSVPKPLIDRMMKAKAAAGDDKKKARELQEQEGLKITVELIHQVLETPGVKGVHIQ
AIEWESAIAGIVKEAGLYPRPEV
>B8NQE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167)|TrEMBL
MGMFPFPLIGGPVKLRPKPFPPRWISPQSSLFNYHLSRNFAGTDSGIKMEKITDKIAALP
PDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGSTAQRSLELAEICQ
RQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNRD
FTFAVDLVRYIRQKHGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTQAGADFIM
TQLTYDIEAYTRFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVQIPPQILA
KLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLRGFHFYTLNLEKTVSFILERCDLIP
PYSEDFDAIEEGGDISAMDGAHLRSLTRRRASSINSLPHNRVIVDKLHASEVSSKASVSH
EAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPS
LHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPE
LLQLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKP
LLQKHGHEKLAWFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTI
IEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNDIKDDVWLVCVVGQDFGAGTEMGSE
EEEDEKKFMWRVLLNAKK
>A0A7Y4SCY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MSREPRRLRDVLDQGQFAVTIEYNPPKGTNISGVLENAKQLVGRVHGVNVTDNTAAIVRA
GSLSVCRLLYELGHDPVMQMTCRDRNRIAMQSDLMGASMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQELNNGRDLVGNKLDGATQFTIGAAVTPEADPLGPMLAKFEVKV
KAGAQFFQTQAIYHPEQFASFMQAVRPFKAKVLAGILVLRNAKMAEFMNANIPGVSVPQE
MIDELRAAGPERAEDAGVDIAVRTIKAVKPYCDGVHIMAIKATHRLADIITKAEVG
>A0A812FGL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. B1REV9|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWSSVHRLKTLNPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDATRDELINIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVASGA
>A0A3Q1C0U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amphiprion ocellaris|TrEMBL
MVNQVQRGDGNCQSCKSDSSGSNSGGESSKESSRCSTPVLDADRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQTKEKITDYLTKAKRLGLKNIMALRGDPLGEDWEEEEEGFNYAVD
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGADFVITQLFFRADTFL
KFLEDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEDITKVIEPIKDNDAAIRNY
GIQQAVEMCRVLLESGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELMSEESVNEIFTCYITAQPNRRGHKVLCLPWNDEPLASETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPVSFMSWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDVPPELLNDGAVSE
>A0A1V5HY79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium ADurb.BinA120|TrEMBL
MKIIDLYRERFVVSFEIFPPKTPQGEEGLRQALDDLSGYQPQYISVTYGAGGSTQEKTLE
LALSLRDAQGILPLVHFTCVGAGRDEIRRYLGQVKDSGIENILALRGDPPRGETRFTPPP
DGFAYASELVSFIRSIDGFCIGVAGYPEKHIEAPDMRTDLDNLKRKVDAGADFIITQLFY
NNEDFYRFMDSLAKMDIRVPVVPGIMPVTGLSQVDRVTSMCGATVPKELLRRLERCEDAD
SICEAGIEYSIKQCVELKAWGAPGLHFYTLNRAQAIKRIMDATGL
>A0A4T0DEN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVNVTWGAGG
STSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILALRGDPPRS
DEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQSHPEHQHA
TYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGLMPIQSYQ
ILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRSGVDILSEMVETLKKNSYSGPKGFHFY
TLNLEKAVAHIVERCKLIGAVNNVAVEDHDTPVANGNGDKKAKARRRSSIANSAPQNRVV
IDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIPWSEEGLN
PETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVEFFCSHED
WTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIEAVSFRAW
AEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLLEA
>A0A4Z1FZ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrytis paeoniae|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHHIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAAL
EEVKNDDAAVRNIGKDLVAEMCRRILEAGVHHLHFYTMNLAQATRMVLDELRLTPSNQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLENSIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHEP
DLTYYAVKKTGDVQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLNESFETSENGD
VDGVRFIEPQTVPLTSGEANGH
>A0A355KUD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKITEILNNGKMSLSFEVFPPKTDTAFESVQQATREIAKLKPSYMSITYGAGGGTSKYTL
DIAEDIMKDYGVPTLAHLTCVSSSKATVQDRIFEMNKRGIKNVLALRGDIPSGMEADDRS
GWDHRYAVDLIREIKESGFDFCIGGACYPEIHPDSSNQKEDIKHLKEKVDAGCEFLTTQM
FFDNNLLYNFLYKIREASITVPIVAGIMPITNAKQVDRAIKLSGSFMPQRFKSLVDKFGS
DPLAMKQAGIAYATDQIIDLYANGVENVHVYSMNKPDVAQKIQSNLSDILGK
>A0A357Z1E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKLIQIISQKKPSLSFEVFPPKNNGRYESLRSAIARIAELSPSYMSVTYGSGGGTSSTTV
SIAAALQKSYHVPVLAHLSCIQSTREGVRSQLDALRAAGIENILALRGDLPPGSEPQAGW
YYRFASELVREIRRYGGFCVGGACYPEGHPESRTQMEDIAHLKEKVEAGCDFLTTQMFFD
NNIYYNFVYKLREAGISVPVVAGIMPVTNLRQIRRILALTGTALPQRFRYILDRFGDNPA
AMKQAGIAYATGQIVDLFANGVPAVHVYSMNNPSVAGKIR
>A0A3C0V7V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MSFKDILNSGKFVVTAEVGPPKGTDIKEMIHHIELLKGKVDALNVTDNQSAVMRICSMAV
CRICLDHGVEPILQMTCRDRNRIGLQSDLLGASILNIKNVLCMTGDHVLAGDHKQAKPVY
DLESVQLLGVVNSLNNGKDMSGNEMKGSTDFFQGAVVTPEANPLEPQLIKFEKKVRAGAR
FFQTQAIYDINKFKEFMQYARKFPVKVLAGIVVLKSAGMANFINNNVPGIRVPIELIDEL
KAAGKEKALDTGLNIAARHIKQLKEENICDGVHIMAIGMEDKVPVIMERAGLL
>A0A5N6UTB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus tamarii|TrEMBL
MHIKEKLAQNEAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAAEGGLRYAKDLVRHIRNKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGATF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYSAFIRRANWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLTAGINHLHFYTMNLAQATQLVLDELKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIQDLSHLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLVE
LNNRGILTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELMIPPYLLEELIARIESNE
DLTYHAVSKTGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDNWYLVNIVNNDFHNTYDLFDLFKDLNVRDFDVEVTADNADSK
SQEIEATEATAN
>A0A428W7I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC 00631|TrEMBL
MALGMPSTRTDHARTVRDLLASGAQSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGSSRDGTVRATERIATETTLTPVAHLTAVNHSVAELRNVIGSYAGAGIRNMLALR
GDPPGDPMGEWVPHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSPDWESDIRHFVD
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSMGIEYATELCARLMGEGIPGLHFITLNHSTATLEIYENLG
LHQRPR
>A0A4S9UA88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMIIEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEITAPEAPQ
KVNGVTNGEKHEEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A4Q0GRV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. UV9|TrEMBL
MTNSSISQLAPNSAEARRAFEEPLFADLAGDVGISFEFFPPKSEKMDAQLWDAIRTLEPL
GPDFVSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGV
RHIVALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDFD
IDNLKRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAG
LCGAEIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYA
ICHMLGVRAKPAATVAAA
>A0A2S1ADL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cytotoxicus|TrEMBL
MKLLDLLSKGIVIGDGAIGTLLHSHGLQSSFEELNISDPDLIVSIHKQYVAAGADVIQTN
TYGANEAKLRTYGLENQVVQINRAAVKLAKAAAKEQNAILGTIGGMKHIGAVTTTNIERE
FMLLEQAGALIEEEVDGLLLETFYDEFELIHAIKVLRKQTDIPIVAQLALHEAGTTQNGN
DVNEILAQLIHNGANVVGLNCQLGPLPMTEALKMISIPKDGYLSAYPNAGLPNYIEGRYI
YEGSPAYFETMTPKFIEQGVRLLGGCCGTTPAHIERMKRAIANQVPVIEKTVVSRPPILH
THSERFRTHSTLAEKAKKQTTVVVELDPPKTLDTQRFFEGAKALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSVLGMEEVLALTGDPARVG
DFPGATSVYDVSSIELIKMIQEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDKALIYEVYKETKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPDQVRERMREHETEADAIEEGIGIAQELIDEALKYFHGIYLITPFLKYEITEHLVKYIK
EKQEVREEVTNETN
>A0A7H1BKK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces xanthii|TrEMBL
MSTLRDTLARGTRTFSFEFFPPKTAKGEQTLWQAVRRIEALAPDFVSVTYGAGGSSRDRT
IDVTERLATETTLRPVAHLTAVGHSVAELRHIIGRYADAGVRDVLVLRGDPPGDPKGPWT
RHPEGLNHAWQLVELVRSLGDFSIGVAAFPEKHPRSADWDSDIRHFVAKCRAGADYAITQ
MFFDVEDYLRLRDRVVAAGCDVPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAR
DRPDVAHEIGVHHATLMADRLLAEGAPGLHYITLNKSTAALDIHRNVLSSRSLHVS
>H5X1S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora marina XMU15|TrEMBL
MSDFAEAVRERLLVCDGAMGTMLHAAGNSLDRSLPELNLSNPELVSTVHESYVDAGADIL
LTNTFGASRPRLAEHGFSGDPGEINRAGVRLARQAARQAGRPIFVGGSVAPAVSAGRRTQ
VGAADRAAAVREQVLALADAGVDLLVLETFGYLDELAEAVVTASAATGLPILAQATFTAE
GHTPGGQTPHEVVTALAELDVAALGVNCTVGPQRMLAVVEQLRRHTTLPLSAQPNAGLPR
RVHGRRFEYSLDHDYFARYARRCAERGVSIVGGCCGTTPGHVRAIAAAVSELDGRRTSRG
RAAKVAVAAPAEQGGLARRLADGDFVVAAEIAPPQGGVAEEAAELAADLRQRGAELILVS
GAGGARAQLNSTSLALHLQSQVGTETIATVTTWDKTIMSLQADLLGAHAFGARTVVCETG
NPPLRGDYPNADGIWEVDSVGLVELVAGLNDGRDCDGLSLATKTSFHIGARCNPGAEDVD
AEIARTRAKIAAGAQFLITRPVYELTTLRWMVAELSDEGVPIIVAVSPLSGFAEAEFLAY
EVPDVTVPISTLSTLAQRERAGDDGRGVGLRLASELVEQARSLADGVLVVVRDHDADAAA
RLLAAATSPPG
>A0A419V326|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinobaca qinghaiensis|TrEMBL
MNLAEEYAKRMLIGDGAMGTYLYEKGYSGSYESLNLSDPDLIKTIHREYVEAGSDIIQTN
TYAANRIKLAKYQLEEETADINRRGVEAAREASEGRTFVFATIGGIQGLQKMEESEAEII
KAFSEQMDALIKAEPDGIILETFYDLQEITAVIKLAKSKTNLPIIAQVALGEVGVMHGGL
PLGEAFKQMTAAGADAVGVNCRMGPYHILRSLEMTPLDENTLYAVHPNASLPDIDDGRFV
YQSNPDYFYEKALDFQNQGIGIIGGCCGTTPEHIAQIAAAVKNTVPKKRAAQAVAQKTGQ
FSIVEPPSTEPSLREKAKQSTTVIVELDPPKKLATSKFVEGAQALYQSGADAVTMADNSL
ASPRVDNLAMGALVKSMTQARPLLHVACRDRNLIGLQSHLMGINALGIHDILAVTGDPTK
VGDFPGATSVYDANSFDLIHLMKEMNKGLSFSGKSLGQNTTFTVGAAFNPNVRNVDRAVQ
RLEKKITAGADYFMTQPVFGEGQFKEIYEATKHMDVPVYIGIMPLVSSRNAEFLHNEVPG
IKLTDTIRQSMAACGEDRALAAEEGIAIAKTLIDEAMEYFNGIYLITPFLRYDITCRLTE
YIREKAAVRTEEKSK
>A0A7K3Y0E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eggerthellaceae bacterium zg-893|TrEMBL
MLDEARRAARPTLSFEMFPPKGVLTVERAREVASELAVLRPDFVSVTCSAGGGGNGSDGA
TTAIAAMIQDEFAVASVAHLTCVGATRQTVADTLADMQARGVRTVMALRGDLPEDVSEHH
GDYELACDLIPELKEAGFCAGAAAYPEGHITCTDHRTSLEHLKAKQAAGADFFVTQLAFD
NEDILQFVDAARRARITVPIVCGVMPFVSKSQITRMVFLCGASLPSPVIKLLARYENDPA
SLAQAGIEYACGQLEGLVAEGVDGVHVYTMNRADVARAAREVVATR
>A0A373W7F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF18-29|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A542SPR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rarobacter incanus|TrEMBL
MTDQDTDCWAVPPLRPTISFEVMPPRRPGLAPKFWGTVDALIGARPDFLSVTYGAAGNDR
DTARQVVSRLVQQAPVLPIAHLTCVGHSRADVVDVVDEFLSAGVRSFLALRGDPPAGQPD
WKPTPGGVNSSVELIALLKDRERTRCAAHPGNALRGAAHPLTIAVATFPDGNPAAGTTRD
QEIERLLVKQAAGASFAITQLFYRARTYAEFVERARAAGVHIPILAGILPATDPTRLLRV
AELSGVRPPAELLDRLSAASSDDERHAIGTQATAALAQSVLDAGAPGLHIYTFNKARPAL
DVLAHLELLNVEPNQPNPLTASAVVKGTPA
>A0A1C6H9C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Butyricicoccus sp|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTNSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEVAAGIQSSLSEILK
>A0A2V1AVK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] haemuloni|TrEMBL
MKISKKLEDAHSCSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYELNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALKKAHASGCQNILALRGDPPLD
GSESTGDFKYAKDLIRYIRKNYGDHFNIGIAAYPEGHPEEEDDLKLLGYLKEKADAGADF
IITQMFYDADNFIKWCSKIRKIGVDIPIIPGIMPISTYSAFIRRAKWSEVIIPKHFLEAL
DPIKDDDYAVREKGTELVGEMCQKLIDSGYVNHLHFYTMNLERSTIMVLEHLNLIEHVKD
NAVVGDELPWRKSLHPMRSKESIRPIFWQNRKYSYISRTSGWDEFPNGRWGDSRSPAFGD
IDLSATELLRQSPKRAYELWGCPQSLEDLSNILISYLQGEIKSLPWSDGPIGDDTEVLKP
ALVEMNRKGIFTLNSQPALSAVKSNDEVFGWGPKNGFVYQKQYLEFFIHKDAVDALLHRV
EAHNAKDAHSIVTYYAVDKNGTLSTNAHDDDINAVTWGVFPGEEILQPTIVEKVSFLAWK
DEVYRLLDEWVKIFHTKAVKEVVEDEKIDSFSKLLTGFGDNFVLCNFVNNDFTSGNNIIF
DLFQDLPVTSL
>R9L3F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium MD335|TrEMBL
MKKQTEHCLTSFLKKDRLITDGSFGTYYADKYQTNDMPELANISQDETIWQRVVKIHEEY
RMAGAMLIRTNTFASNTVLLGADLDAVLENINHAVHFARIAVRNCGNENDCFIAGDIGPI
PLDACYKAEDAEREYYIIGRNFVDAGIDILNFETFPELAQILPAITKLKADARRESRALF
IMVQFSVNQFGYSAGGMSAKRLLAQAAECDAIDAVGLNCGVGPAHMEQIIGGIDQALLRG
KPLIALPNAGYPKRVRNRICFQDQSDYFAYKEAGLCSRFGVDIAGGCCGTTPAYIGLLAQ
QLAQTPKTRKSECAKPQAKTLHVTDNAFFKNKPMGEKLIAVELAPPANADDERVLDAAHF
LADLGVDVLTFPDSPSGRTRVDSVLMAQKVHRETGMCVMPHICCRDKNAIAMRSVFLGAH
INDIHNFLIITGDPVPTLIRQTTKAVFNFDSVGLMNIVHGMNEENFAQAPLTYGGAINQG
RKNLDAETARVHKKMAAGASFFLTQPVFTEEAAARVRRIKNETGARILCGIMPLINRNNA
LFMKNEIAGVEVSDEIIQRYPEHAGREEGEAVGIEIAVEIIKKTSDFADGYYFEFPFNRV
RMLKQILQKL
>H1BEJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium 6_1_45|TrEMBL
MIENYLNTQGYMLFDGAFGTYYAQRYAEDQKPCEMANLNHPKRVAAIHQEYIEAGADAIK
TNTFSANEQHLECSWEMIRRILQEGYRIAKEAAKDKVKVFADIGPIMEQKNVSLAQQYQQ
IVDVFLAEGADCFLFETLLNTQELHAVTSYIKEQCPQACIIVSFAVTADGYSRQGIAMSR
LLQDCLADEHVDACGLNCVCGPMHMKRLLDSIDRTQKPILIMPNAGYPTILANRTYFRDS
STYFAKEMREIWQKGARLLGGCCGTTPVYIQKTREALQEHKIIQKVQQPVQETERIPQED
HNPLRRKLQRKQPVIAVEFDPPANCEIERFMNHVEFLKEAGVDAVTIADCPIARARVDSS
LIACKLHRELGLDVIPHMTCRDRNINATKALLFGLQIEGIRNVLVVTGDPIPSEDRQEVK
GVFNFNSQILAGYIRDLNATMFTSPFMVFGALNLNAVNFEAELAKAKRKVTQGMEGFLTQ
PVHSRQALFNLKRARKELQAYILGGVLPIVSHRNAVYMNNEISGIEVDEEIVAMYEGTTR
KEAQKLAVDISCKTMDEMRPYIDGYYLITPFNRVEIIADMITYIHKQ
>A0A1D8GE92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geosporobacter ferrireducens|TrEMBL
MSLLKETLDRGGFAVTAEMAPPKGTDFAHLLECAKAIKGRVHGVNVTDFQSAVMRATSLV
TCKLLKDEGLEPVLQVTGRDRNRIAIQGELLSASVFGIKNVLSLTGDHTVVGDHPQAKPV
YDLDCIGILQAATILASGKDMVGNELKGTPEFYLGASVTPRFDPLEVQLFKMEKKIKAGA
RFFQTQAVYDLETMREFREKTKAMDGKILAGIIPLKSVGMARFMNNNVPGIHVPEDVIAR
IKAAEDKVQEGIKIAGEFIRQLREENLCDGVHIMAIGAEENVPAILDAAGL
>A0A255G0T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enemella evansiae|TrEMBL
MIDPATAHTPGLLEGFSVEITGKDVPALIEAAPLLPRGTAVNITYLANEDAASRLRAAES
VLSLGLHPVPHLSARRIRSAAELTETLAAYQQAGAADEVFLIGGDPPSPEGPFPDALSLI
ETGVLEQHGVRSVGIAGYPEGHPKIADADLAEAMGLKLDAIAERGMAASIITQFGFDAEP
VLNWIRGLRGRGIGAPVRVGVPGPAGIKRLLGYARRFGVASSAGIAQKYGLSLTSLIGTA
GPEKFLHALDDGLEPDIHGQVLLHFYTFGGVPATARWVHDHSEEF
>A0A1F8SJ15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_19FT_COMBO_47_15|TrEMBL
MSLREKLKNGKFVVTAEIGPAKGVDIHEFNENAELLKDRVDAVNCTDQQSAVMRLGSLVA
CHLLKQKGIEPVFQMTCRDRNRIALQSDLLSAYVMGVENVLCLTGDYVTLGDHPDAKPVF
DLDSVSLLYAARQLEQGKDLAGKELKGTPKFFLGACVTPGADPVEPQLIKMERKVKTGAQ
FFQTQAIYEPKTFEAFMKEAKKFGVPVLVGIVVLRSAAMAKFMNKNVAGIHVPDELIDEM
DKADNKLQKGIEIAARLINEMKGMCQGTHIMAIGLESKVPAILDAAKL
>A0A1V4D496|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces antioxidans|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSRAELRNIIGQYAGAGIRNMLALR
GDPPGDPLGEWIQHPDGLTYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATKLCARLMAEEIPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A2M7AKB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium CG07_land_8_20_14_0_80_40_9|TrEMBL
MKTESKLEKILEKGKFAVTGECGPPKGANAEVIKRKAKIIKDYVDAVNVTDNQTSIVRLS
SIASCAILKQEGLEPIMQMVTRDRNRIAIQSDIFGAYALGIRNILCLTGDHQTFGNHPQS
KNVFDMDSIHLIQTVKMMRDEGKILSGDEIDGELKMFIGAASNPFADPFEFRVVRLAKKV
KAGCDFIQTQCIYDLNKFEEFMKMVRDRGLDKKVHILAGVTPLKSVGMAKYMKEKVAGID
IPDELIDRMKGVPKEKRADEGIKICVETIKRLKEIEGVAGVHIMAIEWEEKVPRIVEEAG
LLPRPSL
>A0A4Q9G7U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. BGI-2|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VQFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1Q3WI75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma sp. 48-14|TrEMBL
MFLEKIKSAESGVLLYGITPPKVGTLPERVAEIAQKTMERLATLDIDALVVYDVQDESAR
TKEERPFPFINALDPFAFASTYLAPLPVPKIIYRPAGKFSATELSEWLEGLHSHNFYPVF
VGVPAPDFPVKTSLQEAYTIWSKHQDTSVIGAVTIPERHNLLNDEDVRMLDKMNCGVSYF
ISQCIFNLDYAKQVIEDLALSCNRQSIKPPTIIFTITACGSAKTLQFMEWLGIHVPEELK
EDLKTSDDILEKSVNICLDIASALTTFCMERAIPFGFNIESVAIRKAEIEASIDIARGIG
QMLKDKGLRKSSRAVPIPTSVNE
>A0A5E4TT56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea soli|TrEMBL
MNDSLDKRTIMTQPSFSFEFFPPKTAEGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQG
TLDTVVEIQREGVEAAPHLSCVGSTKDNIREILQTYRQHGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGEWFHIEVAAYPEYHPQAKSPRLDLEHFAHKVKAGANAAITQYFF
NADAYFRFVDDASRLGVDVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
DSIRAFGLDVVTALCERLLAQGVPGLHFYTLNAASATKAMWQRLGL
>A0A3M2H615|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. AOB-7|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLTLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VGFIREETGEHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIESIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A1Q7SSB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon 13_1_20CM_52_20|TrEMBL
MRLSDRARHHNLVTVELIPDRVVPSDLSLLRGRVDAITVPALRNGHDDPSYPKSFSITPQ
RRSLASASIINRAGITAVPSLTCRDCNTSDLSAIANHVVQGLRNVLIVYGDPFPQPHPGS
YQFAKTNELIREISSLNGGNDPCIGAVTNQHADNRESEISRTISRVDAGADFIVTNVAFD
SESVLEHRDALLEAGLNVPLFIQVSIPLSLDNVLFVSQKFDIPVPVHIRKKLLDDPTGGS
LAVAAEAYEALHGEANGIHFSYLFRRRNPIPTYCHLLETIGIEGPTLAPLATSAVKTYPV
A
>A0A836R9R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MRFGDLFAGVVGPVLSFEVFPPRSDEAARQLDRVLPRLAALKPHYITVTYGAFGGTRDRT
LEIARRVKDEFGLESACHLTCVGLRRSELDGMLADIRAAGIDNIVALRGDPPEGSVEFGS
APDCYRHANELVKHIRRYEQRRGIEPFGIAVAGYPEKHIEAPDMESDLLNLKRKVGAGAE
LVITQLFFDNRHYFRFVERARALGIEVPIVPGLMPIASAKQIERFTRMCGATVPVELRRR
LEEAGEQKDRARAIGTEHCLRQAIELLEWGAPGLHFFVLNRSRQIEQILAQLPL
>I9WZ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. GXF4|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTDEMEKILWSSIERLAPLQPKFVSVTYGAGGSTR
ERTHNTVARMIRETTLKPAAHLTCVDASREEIDAVVQAYWDVGVRHIVALRGDPADGVGH
AYKPHPEGYATTAELVEGIKRIGDFKVSVSAYPEKHPEAATLEADIDALKAKVDAGADQA
ITQFFFENEVYLRYLEKVRAAGITIPIIPGILTVQNFKQAANFARRTGASVPYWLAARFE
GLDNDVETRRLVAAAVAAEQVLDLVDEGVQDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AEKAAA
>A0A7Y5RNV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MALRKEDEVSGPREAMKRDFLKELRERVIIADGAMGTMLMARGLSVAGVPAPALNLVRPT
FIKAIHQEYLEAGAELIETNTFTATRPVLEAAQLGERTRDINIEGVKLAREAAADRAWVA
GAIGPIGPRSQKMEQDEIIAAYREQALALVDGGVDVLLIETFGDIEDARSAVLAARSISR
DIPLILQMAFTLTGSTTSGVTPRAMVEAFKGEPIDVIGHNCGGGERAAAAAAAKLASLTA
KPVSIYSNRGLADLDEHGRPVYITSPDYFARQGEAVIELGVNLIGGCCGTTPEDIAALTA
VLGKKRKPARRATKAATVVTKPEVALPPIVWQTPLTKLAGDGVRVIAEVDPPRGLNYRKD
LEGAHELLAAGVHSITIADNPLGVMRMSNLAMAAILIRELNANITLHLACRDRNLLGSQS
HLFGAAALGITNLLAITGDPVATQAHAESSGVFDVSSQNLMKVIRSMNEGALSPESDGSL
RTKFCIGGAFNSGVKRLDAEAKRAERKVEAGASFFMTQPVFDITTANQILDLLEPLKVPV
FIGVMPLLSERNAEFLHNEVPGITIPDLVRERMRGKKGKEGREEGLKLSKELLEGFAPRS
RGVYLITPMGHYSMVAELARYARSLKLRK
>A0A0D2RMW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium raimondii|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFDRMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFIKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQFPHGRWGDSRNPS
YGALTDHQVHKVVEPLPFSFVWYK
>A0A0N1N0Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea vaviloviae|TrEMBL
MMNAFRPSRHGSRRPKVSFEFFPPKSDEMEVALWESVRRLEPLGPSFVSVTYGAGGSTRE
RTHATVKRMVEETGFKPAAHLTCVSASRDEVDEVIRAYWDAGVRHVVALRGDPAGGLGTA
YEPHPQGYHQTSDLVAGLKRIGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAI
TQFFFDNDVYFRYLDKVRAAGIDIPILPGIVPVQNFKQTANFARKTGASVPQWLADRFEG
LEDDAATRRLVAAAVCAEQALDLIDRGAGDLHFYTMNKADLVYAICHLVGVKPEAVAAQA
AAAE
>K3VM41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium pseudograminearum (strain CS3096)|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDAEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSVEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFNSIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLERLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAVYPEWEATGLEAGGRAEAVNTRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWDYPKTRQDINDLFVKHIQGELSAIPWSE
EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PANEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGSTEASPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNLIHHDY
VNRDALWEVLSS
>A0A350K3E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MRISELYQGGTFGLSVEIFPPRNESGDAELFKTLEELVRYQPAFVSCTYGAGGSTSKRTI
ELCALIQNQLHNTATAHFTCVNSTREELVEWLQNAVDAGITNIMALRGDPPAGQETFVPA
DGGLKYANELVSLIRKHFPDMGIGVAGYPECHPEASDAEVDLTNLKRKVDAGADAIYTQL
FFNNEHFYQFRERCLKAGIDRPIVPGIMPITEYRRIQRIMSMCSSEFPADLVGQLEAVQD
DLEAQFEIGVEYAIRQCEQLIKEGVPGIHFYVLNRSQACKRIFDALGFPETQENIAT
>A0A240DYK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter meluiroseus|TrEMBL
MELSIEFFPPKTPEGENKLRLVRERLSEELKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
ASVAPHLSCVGSSRDSVREMLKQYQALGIKRIVALRGDLPSGMGQYGEFHHANELVEFIR
LETGDWFHIDVAAYPESHPQAKSPASDIGFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YDLGVTQPIIPGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDTASIRAFGEEVVT
DLCDQLLSVGAPGIHFYSLNQADAVLGITENLNLPS
>A0A560B6J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum brasilense|TrEMBL
MTSGTPSVSFEFFPPKTEKMEQSLWQAIQRLAPLSPSFVSVTYGAGGSTRERTHNTVTRI
QKETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPETEGGVGGRYVPHPG
GYAYAADLVAGMRKVADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQFFFD
NDAYFRFLDRCAAAGITVPIVPGILPITNFARAVEFAGKCGAAMPKRFAETFEGLDADPE
TRQLVAATMAAEQCQALQAQGIRDFHFYTLNRSDLTVAICRMLGVKARQPAVS
>A0A2D5A990|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MDDLDSGTAPTISFEFFPPSTPAGWMNLDRRINELVPLEPSFVSVTYGAAGSTRGLTNDL
VVRLLEETEIPAVPHLTCIGHTRDEIDVILERYAEAGVTAILALRGDPPQDGSDPDSGEF
EYASELVQHIQRFGDRHRHPFRIGVAGFPEGHPATPNTLEGMAHLKAKVDAGADWICTQL
FFDNHAFLDWRDRCRIERIDVPIIAGIMPISTRRSVVRMAGLAAGTVFPASLQRALARAD
HDDEDAVAEIGLHWASEQCRDLLDHDVDGIHFYTLNKSDATLRIHRSLGXRXARXLRXRP
A
>R7P9I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. CAG:617|TrEMBL
MRLTVHVMNIIDQITSTRQTAFSFEVLPPLKGTGTEKLYNNIERLMEFGPSYINITTHRS
EYVYKDLGNGLMQRERLRRRPGTVAVAAAIQQKFKVPVVPHILCSGFTREETEYVLLELQ
FLGIRNLLALRGDKAKEDNVFKPVEGGYSHTTELLGQINRFNEGFFENGDPIKVPGVPFD
YGVACYPEKHEEAPNEETDLGWFKRKVELGAQYGVTQLFYDNQKFFRFVERARQAGITVP
IIPGIKPLSRLSQITVVPKTFHCDLPEPLTHELIKCKTDDEVKAVGIEWGVQQCRELIQH
GVPSLHFYTVSAVDSICQIARQIY
>A0A2V7A9J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHEFSRRLEAAPLLCDGAMGTLLYARGVSLDACFDVLNLNNPRVVQSIHADYIAAGADC
IETNTFGANRFKLAVHGMDGRVREINRRGVALARDVRESSGRDVLVLGSIGPLGKYLAPL
GTVTTEEAQAAFLEQAEALLEGGVDAFVVETMSDLDEAALAVTAVRSITDLPIVAQVAFT
DDGATFTGRSAAEVGRFLRMLPIQALGANCSVGSSTLFEVLEQMQPEAGGLPLAIQPNAG
LPSRMGERLIYLSSPTYMAEYADRMVDAGARLVGGCCGTTPQHIAAMRTMLDQKRPGRGG
GARPTVTVRPAAVSESPGLHVARPPTLLGRKLAAREFVVTVELDPPRGHTVEKLVQGAKL
LKERGVDIVDINDGSLGRVRMAVLPTALLVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALDVRNILAMTGDPPRAGDYANATAVFDVDGVGLIEILRRMNEGLDATGSSIGEPTSFWV
GAALNPAAADVEREVDRFHRKLQAGARWIQTQPIYDLELLDRFLARAGGSPVPVFVGILP
LHSARHAEFLHNEVPGIAIPDLVRRRLRESGDGALRAGIEMAQRLVRDVRTRYAGAYLMP
SFGRFEVVAEVLDVLR
>A0A2V2SBW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MSNPLAEALCARRFCYVVELVASGLKREAQLLEVASRLAALPEVVAGSITSYAGGALGHD
PIRVGTAARARGLTPNVHVTCVTEDRHALRKRLDDLQALGIENVFALTGDYPKAGPEQPA
PVFDLDSVQLVRLIGEMRQVGAPFHIAVAVSPFKYVEADSLWQYRKLESKIAAGADLVIT
QVGWDAAKFRELHRYMDERGLTTPVLGNVYVLGPRAAERMASGQPPGCWVSPALLTLVRA
ESLGKDRGLRARLERAARTVAVLRGLGYAGVYLGGTHDADHVAWIIRRSEELAPEWEQLA
DELSYGQREGFYLYSRRPAAAAPSRAALSQALDVMGRLFPVTRETWLRRLLTRLCAWVDR
KPKLARAVERVELAVKRPVFGCEACGNCVLGHMEYVCPQTCPKHMRNGPCGGTQLGRCEV
VDQPCIWTEVYGRARAAGRVDALGVYVPPPDRSLEGTSSWINYFLERDSRPGRSESARDG
REPS
>A0A848V547|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hellea sp|TrEMBL
MEVPRNPAKVGTNPGDPLPRLEGHVSHGRFEQVLRAGQFAVTTEIAPPDSADPTEVLRRA
SLFDGYVDAINATDGSGAHCHMSSLAVCAILTRAGYSPILQVSCRDRNRISIQGDTLGAA
ALGVCSVLCLSGDDVGAGDHPEAKPVFDLDSISLAQTIKIMRDDSQFLSGRKLDLAPRMM
IGSSINPFVPPIANRADQLAKKIDSGAEFIQSQYCFDIPMLKDFMAKARDLGLTEKAYII
IGAGVLPSAKTATWMRSNVPGVHIPDELVRRLEQSEKPKLEGRKICAEIMQQVKEIDGVA
GVHVMAYRQEKWVGDVVKCSGVLGDRKPWAPEQSFANIAAIT
>A0A8F0CL12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Inverness|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2R6IUQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QS_6_71_20|TrEMBL
MALRTRSVDRTGVEELLTSVRFELMPFESFEEEVTHLPDDATIAITTSPQLGIETTVERT
EEAAAAGYDVVPHVAARYVEDRDQLREIARRLTDAGVTDIFVPGGDREEPAGAFDSAHEL
LIALDEMPYEFEEVGITGYPEGHDFLDDDTLAEAMAQKAPYATYIVTQICYDPDAVIEWV
EDVRDRGVDLPVEVGIPGVMNYKRLMGISQKVGVGDSVKFLKKTTGVLGFVKQLVGSRGN
YEPNELVDGLAPHVDDPAYDIRGLHVYTFNQTPDTEKWRRGRLE
>A0A2V6ZM84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPYELSRRLGAGPLLCDGAMGTLLYARGVSLDACFDVLNLNNPRVVQSIHADYIAAGADC
IETNTFGANRFKLAVHGLEGRVREVNRRGVVLARDVRESSGRDVFVLGSIGPLGKYLAPL
GTVTRDEALAAFREQAEALLEGGVDGFIVETFSDLEEVALAVAAIRAITDVPIIAQMAFT
DDGVTFTGRPAAEVARALRGLPVQGLGANCSVGSSTLYEVLEQMHAEAGGLPLCIQPNAG
LPSRIGERLIYLSSPAYMAEYAERMVNAGARLVGGCCGTTPQHIAAMREVLDRRRPPRPE
TRQATVTISPVAVGTAPDLHIARPPTLLGRKLAAGEFVVTVELDPPRGHTVEKLVQGAKL
LRERGVDIVDINDGSLGRVRMAVLPTALLVRDATGLDINMHFTCRDRNLMGIQGDLLGAH
ALDVRNILAMTGDPPRAGDYANATAVFDVDGVGLMEILRRMNEGHDATGSSIGAPTSFYV
GAALNPAAEDVAREIDRFQRKVRAGARWVQTQPVYDLAQLDRFLERAGGSPVPILVGILP
LHSARHAEFLHNEVPGITIPEEVRRRLREAGDGALRVGIEMAQELVRAVRARYAGAYLMP
SFGRFEVVAEVLDAIR
>A0A2A4CV67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudothioclava arenosa|TrEMBL
MSKPNISFEFFPPQTLDASFRLWETAQALAPLKPNFVSVTYGAGGTTRKLTHEAVGAIHK
NYGLNVAAHLTCVEATRAETKEIIDAYAEAGVTEIVALRGDPPKGATRFTPHPEGFASSV
ELIEWLAEDGRFTLRCGAYPEPHPEAADTLADVRWLKRKCEAGATSAITQFFFEADTFFR
FRDACVKEGITAKIIPGILPIQSWKGAKNFARRCGTSIPTWVEEAYEAAIRDDREQLLST
ALCTELCDDLIAGGVEDLHFYTLNRPGLTRDVCHALGVTPDVVLENVA
>A0A7Y2YH25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eudoraea sp|TrEMBL
MKTDLKWLKKKVDLGAQYIVTQMFFDNQKYFDFVTAAREAGIHVPIIPGIKPIAVKRHLQ
LLPQVFRIDLPQDLIEEVEKCRNNREVRQVGIEWAIAQSKDLKAAGAPVLHYYSMGKSDN
IREIAKAIF
>A0A832E787|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenotrichaceae bacterium|TrEMBL
MQSQQKHPKSYSFEFFPPRTDDGLVKLRSVWQNLATVKPDFFSVTYGAGGSTRDNTMKTV
TSIQRDTGIEVAHHLSCVAATFDSIDEILQQFKINGIKRIVALRGDMPSGMHVRGDFNYA
SDLVAFIRKQTGDYFQIEVAAYPEMHPQAENPVADITNFKTKVDAGADRAITQYFYNIDA
YFAFIDECEKNNIDVPILPGIMPIINFSQLARFSDACGAEIPRWMRKRLEG
>A0A0E3Q4S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina vacuolata Z-761|TrEMBL
MLFNFREKLNSSKFLVTAEVSPPKGTRFSVPLEDAHQLKGIADAINVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICVMTGDFPSCGDHPGSKP
VYDLDSVQLLQLVRKLDSSTNFAGNRLDGGTSFCAGAVSGIDPEKPLQLIKLEKKVSCGA
DFIQTQAVYDVGMFEEFMEAISHLEVPVIAGLIPLKSLGMAEFMNRNISGIHVPEEIMLR
IKDAPDPVEEGLSIASETIKELMKLSRGVHIMPIGSHKNTARLLSMAGISGK
>A0A3N4P434|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. RIT388|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRAELRAIAQDYWNSGIRHIVALRGD
LPASSGKPDMYACDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLTRFATMTNVRVPGWMNAMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVIAAA
>A0A412CS65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AF26-7BH|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEIAKIIY
>A0A2U3N3X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter stercoris|TrEMBL
MTKRVPISFEFFPPKTDVGAEKLRIVHAELQKLNPEFFSITYGAGGSTRERTLAAISDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGEHFQIEVAAYPEMHPQSDTFDADIKHFIEKVQAGANAAITQFFFNPDAYFYFV
ERIQKAGIDIPVTPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDVESIKAFGHE
VVINLCERLITGGAPSLHLYSMNQVEPNRQLVLDLGLA
>A0A2D9I686|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MTEVDQIVNFMSTCTLEVTPGGAAKIDDFRAVLRPDQIVYVTFLPGSNFRDTVVTVKKLK
DQGMRPVPHFAARSIPTKAFFEENLKMLTEETGVEEALLIGGGVDNPVGEFSESMEILRL
GLFEKYGIKHLGIAGHPEGSPDIKPAEVIRALLDKNAYAAQSPIDFYIATQFCFEAEPLI
QWDRQIRAEGNTLPIHIGIPGLATIKTLMKHAQACGIGNSMRFIAKQARNVAKLMSVSEP
DKLVRDLAHYKATDPSCGIIQAHLYPLGGLKKSSAWLHAIQDGKIELSKKGGFKTDYVVE
>A0A4V1A8K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. JH2|TrEMBL
MQSQKQFKRRFSFEFFPPKTDAGKEKLQVVRDQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGSRAEISELLDEYKKNGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARSAEDDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMNITIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTVSIRK
FGEEVVTRMCEDLLKAGAPGLHFYTLNQTEPSLSIWKNLGITDREKISF
>L9LX04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. OIFC021|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGIHIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A2E0MMI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pimelobacter sp. (strain R48)|TrEMBL
MDLQRRIVERAGEFLVFAVTPPRLSADAARAQEIADVTAERLRPLDLDALILYDIDDESD
RNPEPRPFPFLPTMDPAAYLEDQLAAWPTPVIVYRATGKYTEDELRSWLQRQDPDRLLSV
FVGASSRDKDVATTLRQAQQVRRETNPDLLLGGVAIPERHIDGREEHLRLMAKQDAGCSF
YVTQVIYNLNAAKTLASDYAYACAEHGLRPVPIVFTFSVCGSMKTMDFLRWLGVDVPGWI
ENDLRHSQDTLDASFEHARATALDLMAFCRRLGLPFGINIESVSTRKVEIEASVRLAVEL
GNELTR
>A0A7X6GXI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibacterium persicicum|TrEMBL
MASPRVSFEFFPPKSLEASFRLWETLNVLAPLAPSFVSVTYGAGGTTRALTHDAVKTIHA
NYGVAVAAHLTCVDATREETLAIADSYAAAGVTQIVALRGDPPKGQGRFTAHPEGFASSI
ELIEALAATGKFHLRVGAYPEPHPEAASMQDCVDFLKRKIDAGASSAITQFFFEAETFFR
FRDACAAAGITAPIIPGILPINSWSGVRKFAAACGTSIPAWLDEAYDKAARDGREALLST
ALATELCTDLIEGGVEDLHFYTLNSPDLTRDVCAALGVAPRVSLSEVA
>A0A2W5RPU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MSLLAQYFAQQQFCVFVEYLSSHQAQWPVKTQFAGFPAAMTLADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDAKTQGQKNLLLLTGDKLKQHCYSHDLEPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYGMTAL
QDAHAFLARHQYAQKILACVMPLTLARAKFMLKHKVAGIVITPHMLQVLQQEKEQGLSDR
VYVRCALQILMCRHLGFAGVHLSACHQPEEQSLLERYIEEYRHLSFAECERLWNTLWQVQ
TGTEFHPKLDCYSRPATSSQIIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDRSRANQ
VLLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTKILKEKLIPTVSIAVRGTSSWKNWYVESTG
>A0A1H1YPZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas asplenii|TrEMBL
MGLLKNALGEQAFVCLVEFVPKPSAQHFGAFEQLMQRSTLCGWPMIAAVADRVGGNLDLS
PLDAIAEFNGSRSALVHFSGKDRERRELLAQLERMAAAGLDELLMLTGDRLPGHDPGQRL
VRYLESVPALQIARQARPEWLLGAALNPFKYCEEEGAAQYFKAEKKLAAGADFLTLQLGF
DIAKQREALAWMSRQATPKPLLACVMGLTKARAAMLDQVAGVVITQSMRDLLEAEEAVSK
AYAQERSISRLALQIIGLQRMGYAGIHLSGVHQLKQLQALEQALTDWQASLHTQAQWDAA
WMASWSMPDIPGVTFHAGASNWRLGESYVQASRREKVRYCLMSGVHSHLFNRTSRLSQAF
GWVVTRPLWSTATGAGWLHRVERSLKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTRLNRCEFGDRECVHSVKYRTAKAVGQEAVLTDRLIPCIEVETRHQSSWPGWFEADVP
VPADGWKAAQG
>A0A8G8QHY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT2-18-3|TrEMBL
MPHTSDPACRKIPFSFELYPPTSDAATSVLHATIERLAAAGPEFIAVTYGANGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSNAEASQLIREFLDAGVRSFLALRGDPPEGIREGEAF
LGDLGSAAELVQLIHRVQAERVPYREAVIPGLPAARTIKREREKVRIAVAAFPNGHPRSR
SATQDIDTLLAKQAAGANLAITQLFFHADHYLSFILRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRQATELARELISGGAPGLHLYAFNQHE
TVLAVLDGCGLLTPTLPSSALPAPHPVKENP
>A0A6I6JNV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio cashew|TrEMBL
MRIPDLIRGLDRPFVSVELLPPRRETEQSGFLAAVEKMKAMKPLFAAVTCGAGGSGSVGT
LQTSRNLAEGHGLTVMPHITCVHSRQETLADQLDAIRTCGIRNVLAVRGDFPAGMDSGPR
GLMHASDLVARIAALAPDLAVGVAAYPDGHPESRSIREDIGFLKFKLDEGASFGVTQLFF
DNRRYFDMLDRLAAVGCDKPVIPSVLPIRSLGQIKRVMELCDAPVPGNILSGIESAHAKG
GDEAVREYGISLAATQISSLLENGAPGVHLYPFNRAEMCVEVMRRAGLTA
>A0A3D4VCS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonas aurantiaca|TrEMBL
MTTAAQHPTPRHALLARLLDPEQVVMFDGAMGTMLYARGVFINLCYDELALRSPELVRDI
HAAYVKAGAEVVETNTFGANRPKLSQYGLESQVALINRRAAELAREAAGEHRLVAGAVGP
LGVRLEPYGPTSREEAGRHFAEQMQALLEGGADCFVLETFGDLDELQQAVLAARAVDARV
PVIAQATIGQDLRTAFGATPEDVAVALDRWGVDIIGLNCSIGPQTILEAIERMAAVTDRK
LSAQPNAGMPRDVAGRRMYMASPEYMASYARHLVNAGAKVIGGCCGTTPEHIKAMVEGVR
PLAPRTRVQVGNTREFAVENAAPVGREPVPLGERSRFGAKLAAGQFVTSVEIVPPRGIDT
SKLELDAQALAKAGVDAINVPDGPRAQSRMGAIATSLIIERHGIESVTHYACRDRNLLGM
LSDLLGASALGLRNLLLVTGDPPKMGPYPDATAVFDIDAIGLTNLVSKLNRGLDPGANPI
GEPTRFVVGVGVNPAAIDPEQELRRFHWKVEAGAEYAITQPVFDPAQLERFLESIHDVRI
PVVAGIWPLVSARNAEFLANEVPGVTVPESVLVRMRKANERSKEHALAEGIAIAREALER
VQSSVQGVQISAPFGRVEYALDVLTARTV
>A0A7S2ABH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stereomyxa ramosa|TrEMBL
MKIIEKINKAEKEDTVIFSLEFFPPKTVDGVQNLYSRLDRMAMLSPSWVDVTCGPNGVTT
EKSLQICSTAQQTIGLETMIHVTCTNVSKEEIEDTLKQAKQAGVRNILALRGDPSKEDRG
VFKHA
>A0A849T2P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilaceae bacterium|TrEMBL
MNNPAISFEFFPPKTTEGIAKLRETRKQLAQLNPKFFSVTFGAGGSTRDRTMDTVLEIQR
EGFDAAPHISCISSSKEEIRQLLSDYKNANIRHLVALRGDVPSGEVSAGDFRYANELVTF
IRQETGDWFQIEVAAYPEFHPESSSPTADLQHFKNKVDAGANAAITQYFYNADSYFRFMD
QCGALGINIPIVPGVMPIYNYTQLARFSGVCGAEIPRWLRLRLQEYGDDMASLRSLGLDV
VTDICEQLLAGGAPGLHFYTLNQAGIISTIVQRLA
>A0A672ZLE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaeramia orbicularis|TrEMBL
IINSNRSISSSDSSGASTSGGDSSKDSSRCSTPVLEADRSDRLRDKMRRRTESGDRWFSL
EFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGL
ESVLHLTCCNQTTHKITGYLEKAKRLGLKNIMALRGDPVGADWEEEEEGFNYAIDLVKHI
RSEFDDYFDICVAGYPTGHPEAGSYEEDLQHLKEKVDAGADFVITQLFFRADTFLKFLDD
CRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRNYGIQQA
VQMCRVLLDSGKVSGLHFYTLNREVATMEVLRQLGLWTEDPRRPLPWAVSAHPKRRVEDV
RPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSTKDALLQMWG
DELMNEQSVYEVFTCYITAQPNHRGHKVMCLPWNDEPLAPETNLLKEELEKVNRRGVLTI
NSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVN
VHGQNRTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWGKLYEEE
SPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQVIDDMFELLDTPPDPLSDGTASE
>Q92AY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHESGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDKAYLAVYPNASLPEVQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLESTKPVLEKEVRPIL
ELVPEEVEDEESGERLLDKVKERLTILVELDPPRTFDTSKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYVQNKQQLQIASK
>A0A3D1WW26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAS
ENDKPASDYAFARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPIAAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLKAAGVDYAARQLCDLKEHGADGLHLYTMNRPEIAATIMERLG
>A0A0T9R940|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia similis|TrEMBL
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIATDYWNSGIRHIVALRGD
LPPNSGKPEMYACDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFD
GLDDDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A2J8GRI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio diazotrophicus|TrEMBL
MGYTHAGHIDALNQNISELSNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLVSAPHLTCIDASREELINIADDYWANGIQNIVALRGDI
PPGGGKPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVMAGIDVEIVPGILPVSNFAQASRFAAQNNVKVPSWMAKQFEG
LEEDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPTR
>D8Q1D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schizophyllum commune (strain H4-8 / FGSC 9210)|TrEMBL
MKISQKIQQSAKDDKVWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPKEKVDIALKDAKAHGCRNILALRGDPPAGKDE
WEATEGGFVHGIDLVRHIRREYGDYFDIAVPGFPQHMTLPKEERDQEMKWLKEKIDAGVN
FIFTQMFYDVQIFIDWVREVRAAGITIPIVPGIAPIQTWNGFLRATSLAKTIIPQHFMDA
LEPVKNDDEKVRATGTKLVAEMCRRILSEDIGIRGLHFYTMNLEKATRMLLEELQLVPRV
ETIKPLPWRQCLTPSRRQESIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVSLHQSMEDAHRLWGEPQTVEDICKLFAKRCRGEVKALPWSEQELSAETTTISEQLA
RMNELGFLTINSQPAVNGARSDDRVFGWGPSNGYVYQKAYLEFFVSPTLLSLLLTYIEQD
SNITYYVINKNGDLRTNTRSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAYELGSQ
WAKVYGPDSPSYKLISEIMDTWYLVNVVHNDFKDRDAIFQPFFKAGEEYAAKAKANGVNG
SAH
>B8F8Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaesserella parasuis serovar 5 (strain SH0165)|TrEMBL
MSYAKEIDLLNQSVADLNGKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERNRTHSIVKTIQQETGIVAAPHLTGIDAPLDELRAIAKDYWDSGIRHIVALRGDEP
AGYTKKPFYASDLVKLLKEVADFEISVAAYPEVHPEAKSAQSDLLYLKQKVDAGASRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMAKMYQGL
DDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGVRPE
>A0A3M2FTL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium J003|TrEMBL
MSVSRFQAACEQGEFLITAEVCPPKGRDASTMLRQAAHLKGRVHAVNVTDGSRAVLRMSS
WAAAYLLQQQGFEPICQIACRDRNRIALQADLMGIAALGLRNILALTGDPVKAGDHPQAK
PVFDLESVRLLRVIGQLNQGVDSEDRPLADGATHFFAGAAVDPQSASWSGLQQRFERKLA
AGAQFFQTQLITDFERLAKFMDQIAAGCGRPILAGIFLLKSAKNALFINRAVPGASIPQH
IIDRLAAAPDPLDEGITIAAEQVQQARELCQGVHLMAVRREDLIPEILNRAGIPPLSASP
APLAKRPHSP
>A0A660N2I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingella sp|TrEMBL
MTTKPFSFEFFPTRTPEGRAKQVITRKQLSQFNPSFFSCTSGAGGSTREGTMQTIGDILS
EGIAAAPHLPCIGMTADEVKALLAQYKAMGVKHIVALRGDIPSGIGLGMDGMRYANELVE
LIKTEHGSDFHVEVAAYPEFHPQARSAEDDINHFVRKVNAGADSAITQYFYNADAYFRFV
DDVQGRGVRIPIIPGIMPIASFAKLARFSDTCGAEIPRWLRLKLQSYADDSASIKALALD
VVTDMCERLLREGAPGLHFYTLNQAGLVSTICQRLGY
>A0A2D3PKG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium pseudoperiodonticum|TrEMBL
MKIADIYKGKSLTTSFEVFPPNDKVGLDQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIADRIKNQNGVESVAHLTCIGAKKEEIDRVLEDLEKHNIENILALRGDYPVDRELEVGD
FSYARDLINYIHEKKDDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A1Y4NC47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelatoclostridium sp. An173|TrEMBL
MKIIDMLLKKPTLSFEIFPPKNHDGDISSIYKTIDELSALKPDFISVTYGAGGSTTEHTV
EIASKIKNQYGIEAVAHLSCIDATSKQLTKILNELKDNNIQNILALRGDYPKDYDPKTAP
HEFKYASELNTFINKNYPDTFCLSGACYPEVHQEAVSLEADLEALKKKVDSGAQYLITQL
FYDNNYYYRLVREARLKGINVPIIAGIMPATNARSLLNIAKLSGGNIPYNLSASLERFRN
NPKAMKEVGLNYATNQIIDLITNGVDGIHLYTMNRPEIAKEILMRTNNIFAEFKND
>A0A2D3LXJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium pseudoperiodonticum|TrEMBL
MKIADIYKGKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKNQNGVESVAHLTCIGAKKEEIDRVLEDLEKHNIENILALRGDYPVDRELEVGD
FSYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>Q5JH49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)|TrEMBL
MVDIQVTTCPKDLLNGPCGGALNERCEVDGKECPWVRILERFNVDPATLFEEHPLLLELE
DLVERDSRPRDSAFWQNLERGRAFSVEFPVAAVSKPEESLQVLREIRANLVTVPDNPLGY
PHYDPIAVACYLKSLGLRSGVMPHITAKDRNLNALTSELRTAQVFGCEAVLLTTGDWPGF
AVPSRPVFDVDASNLIRLARLVFAGVMPTKEVLEVESRPRVASTMNPHYRPKLEARRLAR
KLIAGSEAFFTQVVAAGESATGISKIVEELKKYADVDVPIIASVLYPMKEEMKPFLRALG
IPVGDEPFEALLEELKAVEAVRGLNLIVSSRSLEEWLGLWREAREIIKGVFE
>A0A5J5AS37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nyssa sinensis|TrEMBL
MKVIEKIRAAEGGEKVVFSFEFFPPKTEDGVDNLFEKMERMVAHSPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHGQDK
FVQIQGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDVIQSDGVATLEGYQSDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTK
IPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKILASWD
>F2RI66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)|TrEMBL
MALGTASVRSDRARTVREILASGGTSYSFEFYAPRTAKGEQGLWNAMRRVEAVGPSFVSV
TYGAGGSTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNVLGQYADAGIRNMLALR
GDPAGDPLGEWVEHPEGVRYAVDLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVA
KCRAGADYAITQMFFDPENYLRLRDSVAKAGCETPIIPEVMPVVNVKTLDRLPQLSNAHF
PADVKERILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A1Z8R886|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED34|TrEMBL
MSAPEISFEFSAPRDDAARDKVLTVRDKLSTLDPEFFSVTYGAGGSTRDGTLQTVLALAE
SGTSTAPHLSFGGDDDGFIRELLSQYQSAGIRRIVALRGDVPSGTGPGSHIYADELVTFI
RQETGDHFHIEVAAYPEVHPDSTSPNSDLAYFKQKVDAGADSAITQYFYNADAYFHYVDT
VTALGVDIPIVPGIMPITNVDTLLRFSDKCGADIPRWISQHLMQYRDDKASLQSFTTDLV
TSLCARLLEGGAPGLHFYTLNQSLPTLRIFRQLST
>A0A2Z5QSY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces naeslundii|TrEMBL
MAHLTCIGYRKQEAVEIVTRFLRMGVRRFLALRGDPPAGTRADEVAGELRHADDLVRVIR
EVEADFFGDGKRHVTIAVAAYPATSDHIEAIEVLAAKQAAGADMAITQVFYDAADYVALT
NAASYAGVSIPILPG
>F2RH41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)|TrEMBL
MSPTFSFEFFPPKSPRGERTLWEAIRRVEALSPDFVSVTYGAGGSSRDRTIEVTKRIAAE
TTLRPVAHLTAVGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRGAWTPHPRGFTYAH
ELVELVRSLGEFRIGVAAFPEGHPRSADPAEDLAHFVAKCRAGADYAITQMFFDPEDYLR
LRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAKDDPAAAYRVG
VEHATGMGLRLLDEGAPGLHYITLNKSTAALEIHRTVMSARSVVHV
>A0A4R2L5Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frisingicoccus caecimuris|TrEMBL
MNIQRLFESKKVVYSLEVFPPKKTTSIDTIYNTLYGLRGLRPDFISVTYGAGGSEAQKNK
TCEIASLIRSEYQIEPVSHLTCVGSTKQDIMEFLDRLKAEGVQNILALRGDITPGNDVID
FEHASDLAAFIKNYDDSFNISGACYPEGHCDSANMDQDIENLKKKVDAGVTHLVSQLFFD
NNHFYEFMDKVEKVGIHVPIEAGIMPVINKAQIERTVSMCGASFPVKFSKLLNKYAQDPI
ALKDAGIAFATEQIIDLINNDVRGIHLYTMNNVETATRITNSISNILASCNRQV
>A0A1K1TZ67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces atratus|TrEMBL
MRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPGFVSVTYGAGGSTRAGTVKA
TEQIAADSTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDKCRAGADYAITQMFF
NPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLDRFAQLSNASFPSSLKERILAAKDDP
AAVRSIGIDFATQFCARLRSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A4Q1CJI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacibacter luteus|TrEMBL
MKVTEHIAQAKNTLVSFEILPPLKGKTINSIFDHLDPLMEFKPSWINVTYHRAEQVFKKK
LDGTFEKVEVRKRPGTVGICAALQNHYNLDAVPHLICGGFSKRETEDALIDLNFIGVQNV
LVLRGDAAKNETFFEPHTDGHKYAIDLLKQTINLNHGIYLEDDIRDGFRTDFCAGVAGYP
EKHFETPNQEIEMQRLKNKVDAGAEYIMTQMFFDNSKFFAFVKSCREMGIEVPIIPGLKP
LTSKKQLSVIPRTFHVDIPTELSNEIMRAKTDEDCKKVGTEWLIQQSKELKEFGVPVLHY
YTLGSPKVIYNVVKNVL
>X6KDA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L103C119B0|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDEIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A485M127|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|anaerobic digester metagenome|TrEMBL
MLVREILKEKKTSFSFEFFPPKTPGGWDKLFLTISDLIPLKPSWVSVTYGAGGSTRENTH
NLVVRIKKETDLTVVTHLTCIEATRGDIMAILERYDSEGIYNILALRGDPPLGQSSWEAG
PEGFCYAIDLVAFIKKHFPHMCVGVAGFPEGHPETKNRLQEIEHLKAKVDAGADYIITQL
FFDNRDYYDFCERCELAGITVPIIAGIMPVISRSGMIRMAELAARARIPAALLKSVQRAG
SDESVERVGIHWATEQVRDLIDNHARGIHFYTLNNANATLKIYEALGVDDSSQLA
>A0A2N2PQY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-1|TrEMBL
MSRLGKALTARQFAVTVEIGPPKGADVSHLLATAENLREYAHAVNITDQQSSVMTLGSLA
ACHLLLDLGIEPVYQVTCRDRNRIALQSDLLSAYALGIRNVLCLTGDHVSLGDHPQALPV
FDLDSVTLLCTLRTLETGRDLAGKKLAGVPHFFAGAVVSPGANPLGPQIAKMEKKIRAGA
QFFQTQAVYDPGQLERFIHKVEHLGVPIMAGIIPLKSAGMARFMNRNIAGVEVPDSLIEE
MTGTSDRVLTSISIASRLIRDMKDMCQGVHLMPIGWAKVANSLTDRAILG
>A0A859DQV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caproicibacterium lactatifermentans|TrEMBL
MKIKNLLKPGQVTVSCEIFPPKQGTGLPHAREVVHAIAALQPAFVSVTYGAGGTNCANSI
ELAAEVEKCGVPALAHLTCVSAEKQEVLAVARRFAANGIENILALRGDLPKDDSFPRDGQ
YRHACELITDLKEMGNFCIGGACYPEGHVESANKAEDLQYLKEKADAGCDFFTSQMFFDN
DLFYNFLYRALAVGIHVPILAGIMPLTSAKQMRRCVELSGTYLPRRFLSLVDRFGSDPAT
MKQAGIAYATEQIIDLIANGVEHIHIYTMNKPDVAAKILSNLSHVISSHAD
>A0A7L8V352|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp. FWKO B|TrEMBL
MFQTLIQKLQGNEKYITLETTPAHEPSIDSLISKIKVLELEKHVDGFSATDSPLAKMKYS
SLFASLKIQQTFGKPCLATMTMRDKNKIALQSDLLGANDFDVRAILALTGDPAKMSDQPH
TKGVFEGNSNMLLQIIKSFNHSMDFAGKPFKSEPKPIYPFAVSNSYAKNMQSLQKKLHKK
VQYGALGIITQPIFDIENGKKLLELFDEVKNSFDDDRAKATLILGVFPVTKFRTAQFLSA
HVPGIYVPNDWIDALSEASKISEDEEYKVGMSLSKKLLDDVQKIHPKVHLMTANRFDVAK
ELLS
>A0A7Y6M1Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea montanisoli|TrEMBL
MALGRPSVLPDRVPTVRELLASGGRSFSFEFFPPKTDEGERQLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERVAHDTTLTPVAHFTAVNHSTRELRHLVGRFADAGVRNILAVR
GDPPGDPTGDWVRHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTEFFVR
KCRAGADYAITQMFFQADDYLRLRDRVAARGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPALAARFEAVADDPAAVRQLGIEHGAELCQRLLDEGAPGIHFITFNRSSASREVFQLLS
HPEPVAV
>J0XEF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schaalia georgiae F0490|TrEMBL
MYTSFLERARRAGVTLPVVPGIMPATDQGRLRRVGALTGVEGPQRLLDALASCDDEAERA
EFGAAFGARLVRDVIDAGAPGVHLYTFNKSRPVLDILDLMGITSGTKENL
>A0A158LXH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii NIPH 190|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELIDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A1I0E9Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus poikilotrophus|TrEMBL
MSGLVGSPVGMTGPPPPADGPPTRRGARTALERALRAASYEVLPLRGAEESVVEHVPRTV
PLTVTVTEAKGLVPTLELAERLAGHGFTATPHLAARLVRDAAQLADVVARLRAAGVSGVF
VVGGDATEPTGTFPDALSLLEALETTGHHFETVGIGGYPEGHGHIDPELIERALERKAPH
ATHVITQLCFSAATTAAWARQVRQRGVDLPIRVGLPGAVTRQKLVRLSAGLGLGQSARFL
AKQQSVFWRFFLPHGYRPDCLVEGLAPTLGRPEPDLQGFHFFTFNEVARTEAWRQEWLAR
LSDAGTG
>A0A5C1WJA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labrys sp. KNU-23|TrEMBL
MTGDTRLPHPDDFGPHPAAPLPELPGHTSRGRLERVLRRGEFAVTAELNPPDSANPDDVL
ERVKPFEGWVDAINATDGSGANCHMSSVAICALLTRVGYSPVFQISCRDYNRIAIQGNVL
GAAALGVCNVLCLSGDGVQSGDHPEAKPVFDLDSTALLSTIRTMRDEQRFLSGRKITTPP
AMFLGAAANPFVPPHEFRPINLAKKIQAGAQFIQTQYCFDVPLLERFMARIRDMGLHEKC
FIMVGVGPLASARTAKWMRSNVPGVHVPDDVIKRLEGAQDQKEEGKRLCIDIIQQVREIK
GVAGVHVMAYRQEEYVAEIVHESGVLAGRTPWRRDMAPSPIPHEEMVGAQ
>A0A2I1CGB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus novofumigatus (strain IBT 16806)|TrEMBL
MEKITDKIAALPPNEKYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCLGVAAYPEGHPADSYQDVQDPVRDLPYL
VEKTLAGADFIMTQLTYDIEAYTKFEEMLRNHESGAFKTIPIIPGLMPIHSYKILTRTTK
LSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLNLEKT
VSFIIERCGLIPDYPEDTDAVVDDDYTTAPTAAQNRSLSRRRASSVNSLPHNRVIVDRLQ
VPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQISEGQGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVSGAVARRIWGYPVSRKDISALFRRHVSGDLYIVPWSEGGAEENSS
GLNAETEVIRPELLKLIDSKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFF
CPSKDFQTVLKPLFAKHGHEKLAWFATNVKGQFESSLPADPAHADTIEMNPNNVNSVTWG
VFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRVYPRGTPTERLLEEVKNDVWLVCVVG
QDFGAGTENGSEEEQQETKWMWNVLINSQ
>J2ZJ85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. ICM58|TrEMBL
MPFSDDDYACPCTHDHEPTLLSFEVMPPRKPSLEAPFWDTVDRLLQVRPDFMSVTYGAGG
KDRHNARSTVHRLVRDTPIQPIAHLTCVGNSTSEVVSTVYDYLDSGVRTFLALRGDPPVG
QEDWTPGPGGVASATELIHLIRTVEKRRCNAHPGEALRSAFKPLTIAVAAFPAGNPAAGT
TPQQEVERLLVKQAAGASFAITQLFWEADVYASFVELARRAGVTIPIVPGLLPATDPARL
RRVQDLTGIEVPEYLLTTLADYPHQDARDEFGAVFGSRLVHSVLDAGAPGVHLYTFNKAK
PVLDILALMGVTPDPQWSPTSHPFTRN
>A0A2I8A4D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. CENA543|TrEMBL
MEHSHSCSYSTLNNFRKAAQAGEFLVTAEVAPPKGGNPTHMIEMAATLKGRVHAVNITDG
SRAVLRMSSLVASVILLQNGIEPICQMACRDRNRIGLQADLMGAHALGIRNILALTGDPV
KAGDHPEAKAVFDLEAVRLLQLIRKMNQGVDGNDKPLTDGATDLFVGAAVDPQCASWSGL
QSRFERKIEAGAQFFQSQLITDFERLEKFMDKIASVHNKPILAGIFLLKSAKNAQFINKC
VPGVNIPEHIIERLAKAKHPLEEGVKIAAEQVQIARQLCHGVHMMAVKREDLIPKILDLA
GVAPVNQVLAK
>A0A1M3HJU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus sp. 65-1059|TrEMBL
MSARTYSFEFFPPKTAEGAEKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETVREIQA
DGSEAAPHLSCIGSTEASIRDILNEYKSQGIRHLVALRGDLPSGTMDAGEFNYANELVAF
IRKETGDWFEIEVAAYPEVHPQARSYTEDMINFKRKVDAGANAAITQYFFNADAYFSFVE
DARALGVGIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLESYGDDLASIRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPSTVIWQRLGL
>E4UPV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893)|TrEMBL
MHIKDKLALAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMPREKVDEALQSAFKAGCTNILALRGDPPREKEA
WEQTEGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFIAWVRKCRQAGIKIPIIPGIMPISTYAAFIRRTKWVKCAVPKGWMEAL
EPVKNDDAAVKHIGKALVAEMCRKLLDNGINHLHFYTMNLAQSTSMVLEELNLKPSSETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGQPKSVRDLSDIFVRFLEQKLDRLPWSESGITQESEIIKDDLID
LNNRGFLTINSQPAINGAKSSHPIYGWGPRNGYVYQKAYLELLISPALIDEVIKRIETNE
DLTYHCINKNGELKTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSASRKLIQNTMDTWYLVNIVNNDFHKTHDIFDLFKGLVLEDIGTEVSGTQQTTE
PTKNGTHQQVVSTN
>A0A2P7NYE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas sp. APG5|TrEMBL
MDSQKKFSPTFSFELFPPQTQQGIERLRLTRQQLAQLNPKFFSVTFGAGGSTRERTFETV
LEIQSEGHVVAPHLSCIGSTHQNIRIILEKYYQVGIRHIVALRGDLPSGMAQAGEFRYAS
ELVAFIRQEFGSSFHIEVAAYPEYHPQARSAQTDFDNFKRKVELGANSAITQYFYNADAY
FHFVESCEAAKLNIPIVPGIMPINKFSQLVRFSDTCGAEIPRWIRRKLEGYSDDNASIQA
FGLDIVTDLCERLLKAGAPGLHFYTLNSAHLTSTIWQRLNFKENAQ
>A0A410PYM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminipila luticellarii|TrEMBL
MKISGLLKERASFSFEVFPPKIEQSLEPLKETLDQLYRFKPDFISCTYGAGGTNKGRSTE
LCDMIERSGHDVMPHFTCIGNTKQGVHDFIGEYVSMGVENVLALRGDIPHGLDGTNGDFN
NASQLISFIRENFPSLCLGAACYPEKHMEAVSLEEDIKYLKLKQDCGAEFLITQLCHDVE
AYESFIDQIRKKQIHLPVIVGIMPALSKDGIIRMTVSNGCSIPRELAEIIGKYGDNPEEF
KKAGKEYTIKQILRYKTAGVNGLHIYSLNKYKDIVDILQASDLCR
>A0A4Q2UK58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma sordidisoli|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPIKGDTLKNLLDNIEPLMEFKPPFVDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFSREETEDFLIDLHYLGID
NALVLRGDPAKPFTTFKAKENGYSYASELVEQVANMNRGVYLHEEDTALAPSNFCIGVAA
YPEKHFEAENHDIDFEYLKQKVDKGADYIVTQMFFDNRKYFDFVERCRQHGIDIPIIPGL
KPLSTRRQLQILPRLFHLHMPEELVAAVEACENDQQARQVGIEWGIQQSRELMAAGAPVL
HYYTMGKADNVMQIARAVF
>A0A7G2IT08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKICRHDQRPHSGVDVDHV
>A0A7Y8QF14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. GSSP0090|TrEMBL
MSQLLDKLKHNILVADGAIGTILYSEGLDTCPEAYNITHPDKVARIHRTYIEAGADIIQT
NTYGANFEKLKPFGLEHKVKDIHYAAVDIAKQAANDDTFILGTVGGFRGIKQEDLELSSI
QYHTEIQIETLIDAGVDGILFETYYDLEELTTIIKATKRKYDIPIIAQLTALNTNYLRNG
TEINTALQQVVQSGADIVGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSQF
KYSDNAAYFGKVAEQLINEGVRLIGGCCGTTPEHIQYIKSSVSDLKPVTEKNVIPITKYT
RHSEKTTRKENLTSKVKQRPTIIVELDTPKHLDTELFFRNIKKLNDAQIDAVTLADNSLA
TVRISNVAAASIIKQHYDIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKTQTNFNIAGAFDPNVRKLDGAVRR
LEKKLESGTHYFITQPVYSKEKIKEVYEATKHLDVPLFIGIMPVTSYNNALFLHNEVPGI
KLSEDILEQFEAVKDDKAKTKALSLKLSKALIDTVHEYFNGLYLITPFQKVDYTLELANY
SKSITSTKQEAIL
>A0A841XNS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLKDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVAEQIISQN
>Q87EA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylella fastidiosa (strain Temecula1 / ATCC 700964)|TrEMBL
MIPISFEFYPPKNDDQRAQLDRTANRLRAFAPEYVSCTFGAGGSTLSYTSETVRHLSQHH
GFDAAPHLSCVGGSRQEIRELLKLYRAIGCQRIVALRGDLPSGMGHPGDLRYAADLITFI
RAEHGDHFHLEIGAYPETHPQASNTLNDLHYFKAKVDAGADAAITQYFYNPDAYFHFVDA
VQRLGVTIPIVAGVMPISNFDQLRHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVV
TALCERLIAGGAPGLHFYTLNLAKPSTQVLQRLGY
>A0A1B1IHH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. oral taxon 064|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIRLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A6B2ST43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID10115|TrEMBL
MTALRALIDQDTPSFSFEFFPPKSDAGARTLWKAIRRIETLAPTFVSVTYGAGGSSRDRT
VEVTKRIAAETTLRPVAHLTAIGHSVAELRHIIGQYADAGVRDVLAVRGDPPGDPGAPWT
PHPDGFTHAHELVRLVKESGDFSVGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQ
MFFDVEDYLRLRDKVTAAGCTTPIIPEIMPATDVRQISRFAQLSGAAFPEHLAHRLEAAR
HQPAEGHHIGVEHATAMAQRLLAEGAPGLHYITLNRSTATLEIHRNITDARSTPHDLAAH
H
>A0A4S2CYR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium laevaniformans|TrEMBL
MTASLRLHEATRRCPKRMVHGPCGGVTIDGGCEVPGIRCSFADDAAVLRHLEFSAAEVDA
PVAARDSGDALPVLPRGEASTAFAALVDAGAVITADLPVRSVDPGVITEAGVRLRELTAV
IAGEPPGLREALSPTHKALLLAAAGSRVVAGLTCRDRNRVALEGELAALADLGVSGVLAV
TGDHPASTALPQAQPVFDLDATRLAALARRAGLFVAVAEQPSAPPVDYRPTRLARKAHAG
AELGILNLCGDLAEIRRFTAALATTATPVPVLVSVPVLTSAATTRRLAALPGVGLPDELV
RAVAGADDPVESGIAAAVAWAHRALAIPGVVGVHLSAIAAGATEPPDRADAAELAAVDAL
ASAAARLRAVIAAKTASIA
>A0A1X1QIY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cycloclasticus sp. symbiont of Poecilosclerida sp. N|TrEMBL
MALESHQPISFEFFPPKTEEGREKLLKVSQTLGRVSPTYFSVTFGAGGSTQKGTINTVLD
LKKQGFSAAPHLSCVGSTKGNIREILANYQQEGISRIVALRGDIPSGTLDAGEFRYANEL
VGFIREETGDHFHIEVAAYPEIHPQAKNAQTDLANFKQKVEAGANSAITQYFFNFEAYIR
FVEDCDKTGLNVPIVPGIMPITNYYQLAKFSEMCGAEIPRWIAKRLEGFADDKESIKAFG
TDVVSELSQSLLDYGCPGLHFYSMNQAEASLAICRNLGIENA
>A0A0B3VNJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrisporobacter othiniensis|TrEMBL
MSKLQEAFERGEFAVTAEMAPPKGTDLSHLIECAKMCVGRVHAANVTDFQSAVMRATSLA
TCKLLKDIGLEPVIQMTGRDRNRIAIEGEMLSAGVFGIPNLLALTGDHTSVGDHPQAKPV
FDLDSVSILKTASTLNSGVDSVGLELQGKTDFYLGACVTPEYSPIEVQLLKMQKKINAGA
KFFQTQAVYDIEHMRKFRELTKDMDCKILAGIVPLKSPGMAKFMTANVPGIFVPDDQIER
LKAAGKGNYVQEGIKMAGEFIRQLREENLCDGVHIMAIGAEENVPKILDEAGL
>A0A075V123|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis japonica|TrEMBL
MGRMTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSR
DGTIRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYG
DWVPHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSADLEADTEYLVRKLRAGADFA
IAQLFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTPRTLHTSIKLSGAPAPRRLLDRLE
PLADDPKAFRAAGIDAVTELGERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A507DM30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chytriomyces confervae|TrEMBL
NSDRQSDFDHFVEKCKLADYVVTQLFYDCDLYLEWVKRVRAAGVQIPILPGIMPIQMYGG
FKRMTTLSKTSVPKEVDAALEPIKDDDKAVKEYGVKLAIEMCNKLRAAGQKGFHFYCMNL
EKSVRLILEGLEFVAPVEVAKPLPWNPSLAQNRKNETVRPIFWRNRTRSYVLRTEAWDDF
PNGRWGDSRSPAYGDFDGYGVSLKFTPEEATKIWGTPSKVGDIHELFSKFCRGNLAGLPW
CDKMAPESEGIQGLLSDVNLKGFLTINSQPAVDGAPSNDARYGWGPKNGFVYQKAYIEFF
VSPAALDKLIKKLSVDPFITYYAVNKEGDMKTNVQSDTPNAVTWGVFPGQEIVQPTVVDG
TSFIAWKDEAFELWMQWARVYPASSPSTKLIQEISDSWFLMNVVHNNYRDAGAIWEIFD
>A0A163YA72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tardiphaga robiniae|TrEMBL
MTEINPATPTNLPNISFEFFPPKTEEMDRTLWDTIERLAPLAPSFVSVTYGAGGSTRERT
HATIVRLLKETNLTPAAHLTCVGAPKSEIDDVVTRYHEAGVRHIVALRGDPTTGIGTEYI
PHPDGYKTSADLVASIRNRYPDIDVTVSAYPEKHPESTDFDADIDTLKAKVDAGATRAIT
QVFFDNDLYFRYLDKVRARGIDIPVLPGIMPMHNFKQARAFVTRAGTTVPSWLADKFDGL
DNDAETRKLVATTVAAGQVQKLAKHGVSDFHFYTMNRADLVFAISHLLGFRPNGAQKAA
>A0A2N0HW86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. 64|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRASIRAVLADFKAAGVQRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLQAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKLGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLDGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A227PI19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium araucananum|TrEMBL
MKVTQHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
VMALRGDAMKDEQYFMPKAGGNDYAIDLVKQISLLNQGKYLHEVMDADNRANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFKFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDSCQNNAEIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASHLF
>A0A150HGE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium laevaniformans|TrEMBL
MTASLRLRETTRRCPKRMVHGPCGGVAIDGGCEVPGIRCSFVDDAAVLRHLEFSTAEVDA
PVAARDSGDALPVLPRGEASTAFVALVDAGAVITADLPVRSTDPAVITEAGVRLQELTAV
IAGEPPGLRDALSPTHKALLLAAAGSRVVAGLTCRDRNRVAIEGELAALADLGVSGVLAV
TGDHPASTALPQAQPVFDLDATRLAALARRAGLFVAVAEQPSAPPVDYRPTRLARKAQAG
AELGILNLCGGLDEIRRFTAALATTAAPVPVLVSVPVLTSVATARRLAALPGVGLPDELV
RAVAGADDPVDAGIAAAVAWARRALAIPGVVGIHLSAIAAAASAPTVGAANAAELAAVDA
LASAASRLRTAISADTITAETAGTA
>I4EU72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter marinus|TrEMBL
MTHGPCGGVGVDGGCEAAPGPCVFLGRPTVRWAGDDVHPPAPEAPLLALMRQRPVVVADL
PAAPLSRESLVRGADVLAGSVDAVLLGDSGGARVQFPPAYRAALVQARGVPAWAGLTCRD
RNRVALEGELAALADTGAAAVHCVTGDHTSLGDRPDARPVFDLDSTELAARAATAGLLVS
VAEAPAGPPVAQRPERLAEKVRAGAQVCVVNHCGGPDAVADFVAAAVAAGADVPFVVCVA
VALDPASAAELRRFPGLVLPAGYLASIESARDPHRAGVSAAVALAEACLSVPGVRGVDLS
AVAPPGRELSTADALATIGKALS
>A0A1F9YX26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon RBG_13_57_23|TrEMBL
MMKAGSNLEKVFESGQFAVTAEIGPPQSANPEPLTHHAKMLKGYADAFNLTDNQTAVVRL
SSIASAVIIMREGVEPVIQMTCRDRNRIALQSDLLGAAALGVKNVLCLTGDHQTFGNEKG
AKNVFDFDSIVELQVFDQLRTQGKQVGGEVLKDPPKTYLGCAENPFATPYEYRASRLAKK
VAAGADFCQTQAIFDMDMFEKWMDEVRARGLDKKIHILAGVIPMKSAGAARYMKNKVPGM
IVPDHIVDRMKSAKDAKGEGIKLCVEQIEHLKTVKGVHGVHIMAVAWEDIVPRIVEMAGL
LPRPKFES
>A0A5I5GU96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Oslo|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A239S872|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea sputorum|TrEMBL
MNGSEDNKTIMTQPSFSFEFFPPKTADGAEKLRATRAQLFPLGPKFVSVTFGAGGSTQQG
TLDTVIEIQREGVDAAPHLSCVGSTRDNIRDILTTYRDHGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGDWFHIEVAAYPEYHPQAKSPRHDLEHFANKVKAGANAAITQYFF
NADAYFRFVDDVARLGVDVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
EAIRAFGLDVVSALCERLLKEGAPGLHFYTLNAAAATKAMWQRLGL
>A0A448NRT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kaistella antarctica|TrEMBL
MKITDHIKNANGKTLFSIEIIPPTKGTGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERKTTRMRPGTLGICAAIQHKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGIEN
IMALRGDAMKGQQYFEPTNGGHKNAMDLVHQMNDLGHGKYLHDEKICEESNKFCIGVAGY
PEKHIEAPSMNYDLKWLKEKVDAGADYVVTQMFFDNKKFIEFVKSAREMGIKVPIIPGIK
PIAIKKHLQLLPQVFKIDLPEDLISAVENAKDNAAVKQIGVEWTINQCRELLDFGVDVLH
FYSMGKSDNIKKIARELF
>G9WU75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oribacterium asaccharolyticum ACB7|TrEMBL
MSIVDLFSQKTVFSFEVFPPRRNAPIETIYETLYELQDLRPDFISVTYGAGGGENKQSTI
SIAEHIKNICHVPSVVHFPCIGLTKEDILEKIEEFKTAGIQNILALRGDIPEGMENRGDF
RYASDLVAFLKENGDFRISAACYPEGHIENPDKVADIRNLKTKVDAGAEYLISQLFFDNE
YFYDFLEKCDLAGISVPIEAGIMPVINRRQVLRMAGLCGVNIPKKFQRILEKYEDNSVAM
RDAGIAYAVDQIVDLLTHGVDGVHLYTMNNSYIAREIYKATHSLFNSGEKGEKEGTSASA
>B9JGE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium radiobacter (strain K84 / ATCC BAA-868)|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
SGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFRDYMKKVRDLGLHEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEIIKRIEGAEDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEMVHDSGVLKGRRPWKHEANRTDALVAERLERIREGKEENQQEMAEAAA
HHPPHQTH
>A0A436H0E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.16.1.1|TrEMBL
MNDMRQELIQTRGSATFAFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLATAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLEICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWLRVNER
>A0A654SDK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chrysosporum ovalisporum|TrEMBL
MENTQSSTVLNSFRRAAQAGEFLVTAEVAPPKGVDVTHMISMAATLKGRVHAVNITDGSR
AVLGMSSLVASVFLLQKGIEPICQVACRDRNRIALQADLMGAHALGIRNILALTGDPVKV
GDHPNARGVFDLESVRLLQLIRKMNQGLDDNEKPFTDGATDLFAGAAVDPQCHSWSGLQK
RFERKIEAGAQFFQSQMITDFERLEKFMDTVAVAYDKPILAGIFLLKSAKNAQFINKYVP
GVNIPQHLIDRLAQAKDPLEEGMKIAAEQVQIAGQLCQGVHIMAVKREDMIAPILNLAGV
PPVKKATNVH
>A0A2W7NRS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hwanghaeicola aestuarii|TrEMBL
MTRPAISFEFFPPKSLEASFRLWDTIHALAPLAPDFVSVTYGAGGTTRELTHEAVTTIGK
LTGLKVAAHLTCVDASRAETLEIARSYAEAGITDIVALRGDMPGGKPFAPHPEGFANSVE
LIAALKETGDFTLRVGAYPDPHPEASDPDADVAYLKRKVDAGADAAITQFFFDAETFFRF
RDRCVAAGIDVPIIPGILPIENWKGVKKFAKSCGTPIPEELDRAFEAAARDDRSDLLATA
LCSELCSDLLEGGVENLHFYTLNKPQLTRDVVHALGLAPEAALQKVA
>A0A2G5V0V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis nigoni|TrEMBL
MAILRVNGIDSGDENAVVTEKPVFETSKSWSLKNYELLHERIERLIDEKTPFFSLEFFPP
RFVNGVPNFLERVERLSEGGSVFVDMTWHMGSDPANIDKVTSSSSIAASMLDYCGVDTML
HMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPGTELEDTNQFRALDMIRWIREEYG
DYFSIGCAGYPLGHPQAPSYKADLQYLKAKCDAGANFVITQLFFEPETFEKFVADCREIG
ITKPIIPGIMPIMGYESIKRIAKLSQLEIPDHILEDLEPIKHDDDAVQKYGTERCIEMCR
RLLDNGSAPSIHLYTMNREGSIREILKALGLWKLEGDRVFPWKNRSQHPIRCLESVRPIY
WSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTLRNGDDRLSMFGENIE
SIEDVKRVFINYITQTPNVSGKKVTVLPWTEAETGVQPETSLISEQLVWCNENGILTVNS
QPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSEKLIDIIEREYPVRVNYHAIDK
DSSFDKTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKE
SKSYGVIKSIHDTFRLVTLVDNDFQKPSVLFDVLQKALEQLYQ
>R7G2G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea longicatena CAG:42|TrEMBL
MKISDILVEKTPHLSFEVFPPKTDAAYEGVLKATEAIAELKPSYMSVTYGAGGGTSKNTV
KIASHIKDKYNVPSLAHLTCVSSTKEEVHQVIDQLKAAGIENILALRGDIPQESEFPLPN
HYQYAYELIEDIKSQGDFCIGAACYPEGHVESEHKKDDIAHLKQKVDCGVDFLTTQMFFD
NNILYNFLYRAREKGVTVPVIPGIMPVTNANQVKRILSMSGTNLPERFKAIVDRFGDNPK
AMQQAGIAYATDQIIDLFANGINHVHVYSMNKPEVAAAIQANLSEILNK
>A0A6N3CHC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Intestinibacter bartlettii|TrEMBL
MSKLREAFEKGEFAITAEMAPPKGTDLSHLAECAKLVIGRVHAANVTDNQSAVMRTSSLA
TCKMLKDLGLEPVIQMTGRDRNRIAIESEMLSAGFFGIDNLLALTGDHVCVGDHKQAKPV
FDLDAVSILSTATMMNNGTDSTGLELKGKTDFFLGACVTPEYDPIEVQLLKMEKKIKAGA
KFFQTQAVYDIEHMRKFRELTKDMDCKVMAGIVPLKSPGMAKFMTANVPGIFVPDDQIER
LKAAGKGNYVAEGIKMAGEFIKQLKEENLCDGVHIMAIGAEENVPLILDAAGL
>A0A8C6E2T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moschus moschiferus|TrEMBL
MDRPKPKVFPVGHCCPSLGMRALEAGSGRLSVPPSISRNSAMVNEPRGNGGPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSRDEITG
HLHRAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEGESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQRIRDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLSRPPQDERETAAA
>A0A2N6ECP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MNPSTRRSKLFLERLAAEVLVGDGAMGTLLYSRGVPLEANFEHLNLVGPEQVRRVHEDYL
RAGAQVLETNTFGASSLRLSTIGLEKKVRSINLAGARLARSVAGSDIFVAGSVGPLIRPR
GQDRELAPAEKAEVLREQMEALAEGGVDLFVLETFPGLEDLELALALAVELGLPAVAQMA
FMEGGVTRDGVSAEKAARRLQAAGASALGANCGSGPRELKGVLARMAAVCDLPLSAYPNS
GFPQYHDGRYIYLATPEYFAAAGKEMAEVGAALVGGCCGTTPEHIRALSLALRGVRPGGR
VGAGPAEPAEPRPGVPSPEPERTFLSDWGRRPVITVELDPPRGIDCAKVLAGARALAEAG
VDAISLAENPLARIRLGNMALARLVQDETGVEAIVHVTCRDRNLLGLHSELMGAHLMGIR
NVLAVTGDPVAVGGESGATSVFDLNSIGLLELLSSLNGGRTLFGTELRGRTGFLTGAAFN
PNLPSMEGQLRRLEKKVAAGARFVQTQPVYSVQVLETLLEKTAPLGVPVLVGILPLVSER
NAEFLHNEVPGITLPEEVRRRMRGKQGEEGVQEGIAIARELIEAGGARVGGYYLMPPFGR
VELALALIEVIRSSRP
>A0A416IPU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. AM51-8|TrEMBL
MKIGEFLKEHTLLCDGAMGTYYAAKFHNETLVERENFEHPERIAQIHGEYLDGGARLLRT
NTFATNLNFFDSIEEMENNIMIACQIAKSAVEAYYEKTGLTKETYPVYVAADIGTIYDME
QKDDSNVLAEYHHIVDTFVSAGMDIFWLETQVDVYYLKRLLAYIKEKAPQAYVMVSFSMD
KTAYSKGGLQFDRMVRLMSEMDEVNAYGLNCGMEAAHMYQLLKNVNFPSEKPVIALPNAG
YPYQLRGKTIYGKNESYFQKMVLQIADLGIDLVGGCCGTTPDYLKEIAEQLKGKKKIEKK
TGSPETPAVSRTESVFWKKLQSGEKPFVVELDPPSDIKVEKLVSGAQLLKEHRVDLLTLS
DSPMARSRMDASLLGSKIQRETGIYVMPHLSCRDRNVISLRGTMLGDYVNDLRHFLVVTG
DPIAQNDRNTITQVFDYNSIKFMGLLQEMNEDQFYQDRIVYGGALNYQGVGVDAIARRMK
LKMEQGCSFFLTQPIYADADVERIKDLKERTDAKIIGGIMPLVSRKNALFIANEMPGMHV
PPETLAYYEEGMSRSEYEEVAIRVSVEIARKMSSIVDGYYFMTPFNRVELICNIIERIRE
ENL
>A0A6M8HVT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lichenicola cladoniae|TrEMBL
MPPLERWLTGPRVAGLPAPNADRTPPVLSFEFFPPRTDVLEQQLWACIRRLETLRPSFVS
VTYGAGGSTQARTHDTVARLVKETDLTPAAHLTCVDASRGEVDDVARRYWDCGVKHIVAL
RGDPTVKGGRFESHPDGYASAAELVAGLKRVADFEITVAAYPEMHPEATSPQADLDNLKR
KLDAGANRAITQLFFDVETYLRFLDQCLAVGITAPVVPGIMPVSNFGPAKRFAESCGARV
PDWLESMFAGTEGDLETRRMIGVAIAAEQVRLLQANGVDEFHFYTLNRPDLTYAIAHILG
VRPVQAEPPLVMPAG
>A0A7S7NTN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paludibaculum fermentans|TrEMBL
MSDTTQKTSRAAEFRQLIGQRAVIADGAMGTMLYTRGVFINRCFDELNLSAGQMVREIHQ
EYVRAGAEVLETNTFGATRARLATFGIADKVEAINRAGVRLAREAAAERSDVFVAGAIGP
LGVHLEPLGPTSYAEAREMFREQIAVFLDEGVDLLIFETFSQLSELREGLAAARDLAGPE
MVIVAQVTIDDDGNMPDGTTTETFTQFLDSSPADVVGLNCSVGPKATLETLERMMTFTGK
PVSGMPNAGHPTQVEGRAIYLSSPEYLAQYARRMLWAGVKMVGGCCGTTPEHIKSIKSEA
RSLQPGIHKLSVTVEEPKAKAKSMEKVPVAQKSSLGAKLAAGKFVAFVEILPPRGVDPAK
EVAGARLCKDAGIDVINVPDGPRASARMSAQVTCQLIERDAGIESVLHFCCRDRNILGIQ
SELLGAHAAGIRNLICITGDPPRMGSYPEATAVFDVDSIGLANIVNNLNHGLDIGGNPIG
SQTALLLGVGANPGALNIEEEIRRTEWKVQAGAEYIVTQPVFDIRQVERFLRKIEGFRIP
VITGIWPLTSFRNAEFMVNELRVPVPDEYMDRMRGVEDPERARAEGVKIAQEMVANVRPM
VDGVQLSAPFGRYAMAVEVAQAIGSR
>A0A2N5CIQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus pauculus|TrEMBL
MTDRYYSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQRGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRDILKTYRDNGIRHIVALRGDMPSGMGDIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQARSPRHDLDNFVRKVKAGANSAITQYFFNADAYFRFVD
DVRAMGVEVPIVPGIMPITNHSQLMRFSEMCGAEVPRWVAKRLESFGDDKESIRAFVLDV
VTALCERLLASGVPGLHFYTLNTAGATKAIWQRLKL
>V7F4W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSJC264A00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>X5QQ07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSJC269B00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A1Y2CRA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoclosmatium globosum|TrEMBL
MKITEKIEKALAEDRCFWSFEYFPPRTETGAINLFDRMERMYSLGPEFIDVTWGAGGSTS
EATLQCVTTAQVAIGLETSMHLTCTNMPKSKIDDALKQCKEVGIMNILALRGDPAHGQAT
WTATEGGFANAIDLVKYIREQYGDYFCIGVAGYPEGHIENPNKEADFNHFIEKAKLADYC
VTQLFYEPELYIKWVEKVRAAGCTIPILPGIMPIQAYAGFQRLIGREKTYVPPEVLAALE
PIKDDDKAVKEYGVKLAIEMCNKLRAAGQKGFHFYTMNLEKSVRLIVEGLGFVAPLENVK
PLPWNPSLSKKRKLESVRPIFWRNRTRSYIARTEAWDDFPNGRWGDSRSPAFGELDGHST
HLKATGEEAIKTWGTPKTLPEICNLFAEFCKGNLSSLPWCDTMAPESLQSKRNSPVDGVD
SSDIRYGWGPKNGFVYQKSYVEFFVSPEALDTLIKKLSKNPYITYYAVNKQGQEIVQPTI
VDGDSFMAWKDEAYELWAQWGRVYEKGSESATLIEGITESWFLMNVVNNNYRDGSAIFEI
FD
>A0A496S4U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MSLLKEKLEKGDFVVTSEIGPPKGVNIEPYLEEADKLKGKVTAINVTDIQSAVMRLGSLA
VCHLLKERGIEPVYQLVTRDRNRLALQSDLLSAYVLGIENVLCLTGDHPVLGDHPQAKPV
YDLDSVQLLKAAKSLNEGEDMVGNPLEGRPQLFLGAVVNPGIEPLEPQIIKMKKKISAGA
QFFQTQPVYEVDKFARFVEKVKDLGVPILAGVVLLKSAKMAKYMNENVSGVNVPQELIEE
MASVSKEDRPKKSVEIAVRLIKKLKPLCQGIHIMPLGWDRYVPDILKGIDLA
>A0A1X3LP50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli TA249|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1M6GJS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tangfeifania diversioriginum|TrEMBL
MKVIDIINNAKKPVFSFELLPPLKGNDTSRIYRTVESLTEFDPKYINITTHRDEVEFYEQ
PDGAIVKRTTRKRPGTVAIAASIQHRYGIPVVPHILCGGFTKSETEYVLIDLHFLGIENV
LALRGDGVKTQHVFKPEPEGHAHANELVEQIVNLKNGIYLEKDLKNNTPLDFCIGVAGYP
EKHFEAPNMDQDLAYLKQKVDAGAEYIVTQMFFDNRVYFDFVERCRAIGINVPIIPGIKP
INLKNQLTVLPKIFSIDLPAELSGELAKCKNNEEARQVGTEWAIHQSKELVKHNAPSLHI
YTYGVSDNVKKIVKAVF
>V7F645|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSJC264A00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A2E2WNR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Legionellaceae bacterium|TrEMBL
MSLEISFEFFPPKTEVGQAKLEQTCALLCAFQPSYFSVTFGAAGSVQSKTLETIELLSTL
GVNTAPHISCIGTQKNDINKLLDKYQSLGVRRLVVLRGDYPEDKQATAGEFNYANELVAY
IRHQFNDKFHISVAAYPEFHPQALNAMVDFQHFKYKVNSGANEAITQYFFNIDAYDRLLT
LCERANIHVPITPGIMPIANLEKLLRFSALCGAEIPLWLKKRLLAYENDQESLIKFGVDV
VSELCEKLIKLGAPGLHFYTLNQAEPTISILKHLNVDSL
>A0A4D9D942|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nannochloropsis salina CCMP1776|TrEMBL
MKQAEEAAALNPHHKPPTYCSFEFFPPKTAAGVENLYMRIDRLASLEPLYIDITWGAGGS
TADLSLQIAANAQRYLGQEVLMHLTCTNLDVEALKAILNAARQAGIQNILALRGDPPKGA
ISWESCQGGLGHAIDLVRLIREEHGDHFCVAVGGHPEGHQREGLADEGEGATGLDLDKEI
EHLKAKIDAGADFIVTQFFYDVEVYLDYVARCRAAGITCPIVPGVMPIQNYTLFRRMTSF
CRTRVPAEMWEQLAPIKEDEEAVRRWGVSFLTKLCRRLLDAGVTPNLIHFYTLNLEKSVR
LILESLGLTATASTRRQFPWRSSKLSSRAGEDVRPINWANRPKSYLSRTEEWDEFPNGRW
GDGRSPAFGELSDYQFVDTSLGSREDRRAMWGEAPLKDVEVFEGFVKYVRAEIPLLPWCE
VPLQAETETISADLVKINKAGFLTINSQPAVNGALSDDTVFGWGGPGGRVYQKAYVECFT
SQENLKLLMELCEKKPNLHYYAVDVAGNTYSNGSKKATALTWGVFPQCEILQPTIFDPNT
FLVWKNEAFQLWTSIWASIYDDESASNALIHKIHDTYFLVAIIDNDFSSTASMWSVFREI
IDEKEGTPLGGSQHHPQYSLP
>A0A7H8GXX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces harbinensis|TrEMBL
MALGIPSTMNDRAHTVRDLLAAGKRSYSFEFTPPRTEQGERTLWNAIRRVEAVGPTFVSV
TYGAGGSSRERTVRATERIATETTLTPVAHLTAVNHSVSELRNIIGQYADGGIRNMLALR
GDPPGDPMGEWVPHPRGVMYAAELVSLIKESGDFCVGVAAFPEMHPRSTDWETDIRHFIN
KCRAGADFALTQMFFNPEDYLRLRDRVAAAGCDVPIIPEIMPIANLRQIERFKQLSNSTF
PEELENRLRAVKDDPMAVRSVGIEFATELCARLMEEDIPGLHFVTLNTTLHSTATLDVYK
NLGLHRADLEHG
>A0A847CI13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MSTAFSFEVFPPKKTMRIETIYNTLGELRNLKPDFISVTYGAGGSVSDSNTINIANYIKE
VCGVKPVAHMPCLYMTKEKVLDTLLHLKQNGVDDILALRGDAIADSVPVGDFKYASDLVK
FIKLNESSIGDGKGFTIYGACYPEKHPESKNVIEDISYLKQKVDSGVTHLLSQLFFDNSN
FYRFVESARLGGINVPIEAGIMPVINKKQIERMASICGANLPEKFIKVMNKYEDSPEALR
DAGIAYAVDQIVDLVANGVEGVHLYTMNNSYVAQKINDAVRSLF
>A0A3N5AJ66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TLI_185|TrEMBL
MGAAGLRALLDSVRYEVLPARATEDKVLAHVPRDVVVTVTASPVKGLEPTLELTGRLAAH
GYRVVPHVPARLLRDEVHLKEVVERLREAGVDDVFVPAGDAEPPAGAYDGALPVLRRLTE
LGDPFARVGITGYPESHPLIHDDITIQAMWDKRAHATYIVSNLCFDPRVLGEWIARIRRR
DVDLPVYVGVAGPVQRTKLLAMATKIGVGESTRFLTKHASWFLRFAAPGGYSPQRLLERS
EGALTAPSAGVAGLHLFTFNQIAETEAWRCAVLERLGG
>A0A7H1NPD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Entomobacter blattae|TrEMBL
MAIFFITGHGVTRISIELVPRSQDVLLSEAKTIQTLCPDICTINIPDLLQFSLRSYDACS
KVSAFFSSCIPHIRAIDINPLAPLPGHDRPELKEVLVIKGDPPKNMQRRIYSHTSEAIIR
RYKKELPHLKVYAAFDPYRRSPKEEMAAIQRKEDAGADGFFTQPFFDTHYLKTCMDWMEG
KNVFWGICPVIGENSQAYWENTNNVIFPSGFLPTMEANISLGQAIMNTLTAHNANTYIMP
VRVKLETYLSKLLAV
>A0A7T6ZCV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salicibibacter cibi|TrEMBL
MMNQQSSIELFGQMSEPRFELIPTHDIVDRATAALPPHAMLTITCSPTKGVDTTIETAIA
LAPRFTRVVPHIAARMVRSEEHLEAVLDELQAHDVDEIFVVGGDQEQASGPYRHGLDLLQ
SLATREHGLLRIGIPAYPEGNPNIDNDTLAKDLLAKAPLAHYAVTQMCFDPDKVLAWLRR
QREAGLELPFYLGIPGPVKPDKLIRIATRIGVTDSLRFLRKNLKLTGKLLRGYDASGLMN
AYTPHLNDSDYGIAGFHMYSFNELNSLKKIFGRIAI
>A0A4S8MR38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dendrothele bispora (strain CBS 962.96)|TrEMBL
MKITEKIKQCEQKDRVWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTAEMVKTCQKLIGIETCMHLTCTNMPKEKVDIALREAKASGCRNVLALRGDPPMGKEE
WEAVEGGFVHGVDLVRHIRREYGDYFDIAVAGFPQHMLLPKEELDQEMQWLKEKIEAGVN
FIFTQMFYDVQIFIDWVKAVRAAGITIPIVPGIAPIQTWNGFQRATSLAKTIIPQSFKDA
MEPHKSNDEKVREIGTKLVADMCRRILNEDLGIKGLHFYTMNLEKATKMLLEELNLVPRV
ETLKPLPWRQSLTPTRRSETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGEPNSVAEISELFAKFCLGQLAALPWSDQPPAVETSTISERLA
HMNKLGFLTINSQPSVDGARSDDKVFGWGPINGYVYQKAYLEFFVNPALLALLLKQIERD
SNITYYVINKKGDLRTNTHSDGPNAVTWGIFPGKEVIQPTIVEAVSFMAWKDEAFELGHQ
WAQLYDPNSASRKVISDLMDSCYLVNVVHNDFRSPDAIFEPFFKAGEEFLASMKTSPVVN
GNVNGHAA
>W0PAV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Advenella mimigardefordensis (strain DSM 17166 / LMG 22922 / DPN7)|TrEMBL
MSSFSDEAFSLEFFPPRDQVSRERLVGTAKQLMAMHPRYVSVTFGAGGSTRDGTAETVSM
FSQLGCEAAPHLSCIGASKAALVQLLDHYKASGIRRIVALRGDLPSGMGGNDSDYRYASD
LVGLIREHSGDWFHIEVAAYPEMHPQADSPQHDLDNFVTKVNAGANSAITQYFFNADAYF
DFADRAAQRGVTIPIVPGIMPITNHTQLLRFSQMCGAEVPRWIRLRLAQFGDDKASIRAF
GADVVTQLCQKLIDGGVPGIHFYTLNNAEATLSIWKNLHY
>A0A3A5QUM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AM54-2NS|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIDKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHALELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMDHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A435SZ47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.007.01.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A0X3TAJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomicrospira sp. WB1|TrEMBL
MQSQRQYPQKISLEFFPPRTDRGVEKLQSTIEQLDVIHPEYMSVTYGAGGTTQARTMETV
EHIQTRTNHAAAPHITCIGASRESVSELLAQYKAMGIKRLVALRGDLPSGMMDPGEFKYA
SDLVAFIRETTGDDFTIEVAAYPETHPQARNCDIGIKWFKYKVEQGADAAITQYFYNVDS
YRYFIDNCEKAGIDLPIVPGVMPITNYENLVRFSQGCGAEIPRWLKCRLESYEDDPDSLK
AFGKEVVQELSQRLLDIGAPGLHFYSMNQPQPTIDIVQSLTLRQD
>A0A2N2G3J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-24|TrEMBL
MHKKIQEGALGLISQPIYDLENAKMLLESFENAKSEVSSHKQEAQLIFGIFPIVKLRTAL
FLSAQVPGIHVPQYWIDALEKANAKSEEEERKVGLELNHKLFSEIKKFHPKIHLMTANNF
ELANELITNG
>A0A258C3W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacterales bacterium 32-67-6|TrEMBL
MTFIPPNALGPVARTGAGVGPRPSVSFEFSPPKGPKSEASLWEAIRRLEPLNPTFVSVTY
GAGGSTRDRTHRTVVRMLKETTLKPAAHLTCVEASREEVDEVIRDYWEAGIRHIVALRGD
PPGSLGGAYTPRADGYQNATELTAGIRAIAPFDVSVGLYPQIHPESPSVDHDIEVLKAKI
DAGATRAITNFFFDIDGYLRFIDKIRKAGVTIPILPGIMPVSSFEGLSTMSQRIGVTIPG
WLSNLFEGLDEDPETRKLVAASVAIEMCARLTEEGFSDFHFYTLNRADLVYAICRVLGVR
EAGPAAEVAA
>A0A0N1BXU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. AAP93|TrEMBL
MTTTFDQLREARTALDTPLFAGLPGDIRVSFEFFPPRTDPLMEQLWDVVTTLAPLRPSFV
SVTYGAGGSTRDRTHGTVARIIKEARLPAAAHLTCVEASKAEIQEVAESYWEAGVRHIVA
LRGDMGAPGVPFTPHPDGYANAADLVAGLKKIAPFEISVAAYPECHPDSPSVEADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDRLAAAGITAPVLPGILPVSNVAQTRKFAAACGAH
IPAWMDGLFEGLDHHPSSRQLVAATVCAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPERAPLEQAA
>A0A1Y3X735|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. An51A|TrEMBL
MKVINLIKSSEKTAFSFEILPPLKGTGIEKVYETIDLLREFDPKYINITTHRSEYVYTEL
GNGLFERKRVRRRPGTVAVAAAIQNKYGIPVVPHVLCSGFTREDIEYMLLDLQFLGITDL
LVLRGDKAKHQSVFTPEPGGYSHAIELENQINDFNRGIFIDGSPIKEPVHPFGYGVACYP
EKHEEAPNMEQDIYWLKQKIESGAQYAVTQLFYDNAKYFAFVDRLRAEGINVPIIPGIKP
FGKLSQLSVIPKTFKVDLPQTLVAEAMKCHTDAEAAELGVEWCINQCRELMRHGVPSIHF
YTVGAAQSVSRVAKAIY
>S6AEP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuricella denitrificans (strain DSM 22764 / NBRC 105220 / skB26)|TrEMBL
MTTSSLLTPHSSPILSFEFFPPKTQEGMDKLHATRKQLGQLNPEFFSVTFGAGGSTRDRT
LETVIEIQREGHKAAPHLSCIGSTRESIRAILNEYKSHGIRHIVALRGDMPSGMACAGEF
RYANELVEFIRAETGDWFHIEVAAYPEFHPQAISAQTDLANFKRKVDAGADAAITQYFYN
ADAYFNFVDECQAMGITIPIVPGIMPIGNFSQLARFSDACGAEIPRWLRLKLQGYGDDSA
AIRACGLDVVTGLCERLLKGGAPGLHFYTLNQAGLISTIWQRLGL
>A0A523NAZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MKVIDHLNNATDPLISFELIPPKRGGDIKSVLGVLDEVIKYHPPFIDITSHSAEVIYEET
PEGIKKKVKRKRPGTLGICALIQNKYNVDAVPHILVKGFTREETEDFMIELNYLGIDNVL
AIRGDDSGYEKPIPLGKSTHHSSLDLVKQIFDMNHGKYLEDSLLDAKETNYCVGVGGYPE
KHFEAPNLKSDIKFIKDKVDAGAEYVVTQMFFGNNFYFDFLDKCRAAEIDVPIIPGLKII
TSKKQLHSIPKNFHVSIPDELADEIDSANSEDILNIGVEWAAKQVEELLSKKVPSVHFYI
MLNPKPIKMLMDRLKLF
>A0A1W2BNN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. B1|TrEMBL
MNASYDQLREARTALDTPLFAGLPGDIDVSFEFFPPKTDALMAQLWDVVETLGPLQPKFV
SVTYGAGGSTRDRTHGTVARIIKEAKLPAAAHLTCVNATKAEIREVAESYWEAGVRHIVA
LRGDMGAPGVPFTPHPEGYANAAELVAGLKQIAPFEISVAAYPESHPDSPSSQADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAAACGAA
IPAWMDGLFEGLDTHPASRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPKAPALEKAA
>A0A8D9P2M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEL
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A672LA97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus grahami|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDTDRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAETFLRF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGI
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFATDQL
>A0A0N0S3C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus contaminans|TrEMBL
MGLLEKLKTHVLTADGAIGTLLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLEEI
LTTVEEQATVLLAGNPDGLLLETYYDIEELAATLKMLRAKTKLPIIAQVSMHDPGVLQNG
MSLNQALHELEALGADIVGVNCRLGPHHTIQAFEGVELPEKAFMSAYPNASLLDVEDGRV
VYESEADYFGRAAVALRDQGVRLIGGCCGTTPKHIAAAKKYLEELTPVQKKSAKPEKIEV
VREAEPAKYEPLHEKVKRERSVIVELDTPRHLEIDGFIEGAKKIYEAGADVVMMADNSLA
SPRISNIAMGALLKHTHSVRPLTHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKIIEIYETTKHLETPIYIGIMPVTSYKSAEFLHHEVPGI
KLSEDALERMKACGDDKELATKEGIAIARELVEVAAEYFNGIYLITPFLRYDMTLELMSY
IEQLDEQKKGVRING
>A0A7J5URS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Georgenia thermotolerans|TrEMBL
MPPLSLMSVSVATHPTVSFELFPPRRPELDETVWQRVLRMADAGPDFFSVTYSVSAAARA
ASAELLRRLLAQTRIPPIAHLTCVAATRAEIAARVGRLLDAGVRDFLALRGDPPPGETAW
HAPPDGLSRSSELVALIREVEAERREDGCLRAAAPSVVALDLGVTPADVVSVAVAAYPSG
QSHTRRAELAALREKQDAGADFAITQVFYDAEAYASLCADAHAAGVHIPILPGILPLTDR
RRLHRLEELSGVPVPVTLDALLDTDEDAERLRRGIDATLALIDRVLAVGAPGLHLYTFNQ
DRPALDVLEHLRARGIRNPALETRPAVPPART
>A0A1Q8JU58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. Ae356_Ps1|TrEMBL
MSDSFLIPDNHIGRATVSSIAVANEVQAMGGNSIACVNSRDRNLLGFRRDLLTAAAYGVD
QFLFVQGDKPSVGDRTGELKVRTMVEEARAATDQDQFAGVDPFRLGVTAGHRRRMATWKQ
AADFVVVQIGYSVDAFLRWRDANPTDLPVYAGVMVLASAGMATRLRESIPDIEIPDDLVD
RVSSSPGAGVDAACEQIQALRDTGAFAGAHLVPVSRFRETAAQLERQR
>A0A150X2Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivirga echinicomitans|TrEMBL
MKVSQHIKRAKGKTLFSFEILPPRKGENVNGIFDAIDPLMEFNPPFIDVTYHREEYIYKQ
HANGLLEKVTTRKRPGTVGICAAIMNKYGIDAVPHIICGGFSREETENALIDLDFLGIDN
VLVLRGDAIKSEGRFVADPDGHSFATELMQQVLDLNQGKYLNEEAEMAKTNFSMGVAGYP
EKHFEAPSLKSDMKYLKQKVEMGAEYIVTQMFFDNQKYFDFVEKCRKADINVPIIPGLKP
ITTLNHSTILPSIFDVDLPDDLVDELDKCKDNKAAREVGIEWCIQQSKELMAAKVPCLHY
YTMSKSQIVKQIASELF
>A0A506PEF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paucihalobacter ruber|TrEMBL
MKVTEHIEKANGKPLFSFEILPPLKGQNIQSIFDGIDPLMEFKPPFIDVTYHREEYDFKE
LPNGYIEKKVVKKRPGTVGICAGIQNKYGVDAIPHVLCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKDGHSYASELVTQINNLNNGVYLDEDLQNSTCTNFCIGVGAY
PEKHMEAPSLDSDIHFLKQKIKNGAHYIVTQMFFDNKRFFDFVLKCNAAGINVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMEIVRAKDNDSVKQIGIEWCVQQSKELIEAGFPVLH
YYSMGKSDNIKAIAEQLF
>A0A6B3ALW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8111|TrEMBL
MALGTASTRTDRARTVRDMLAGGKTTYSFEFSAPKTPKGQRNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVHETEQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNAVF
PDTLKERILTAKDDPATVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>S8F9X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium oral taxon 272 str. F0290|TrEMBL
MSVIDFIKHTDRTAFSLEVLPPLKGTGIEKLYQTVDLLREFDPKYINITTHRSEYVYKDL
GNGLYARHRVRRRPGTVAVAAALQNKYNIPTVPHVLCSGFTREDTEYQLLDLQFLGITDI
LVLRGDKAKDQAAFVPEQGGNAHAIDLEKQINDFNNGLFVDGSPIIVTGTPFHYGVSCYP
EKHEEAPNMEQDIYWLKKKIEAGAEYAVSQMFYDNRKFFSFIKRVRKEGIRVPIVPGIKP
LCKLNQITMIPQTFKIDLPKELAAEAIKCKTDEEAKALGIEWCIYQCKELIAHRVPSIHF
YSMGAAESIKQIAQAIY
>A0A163QNN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oerskovia enterophila|TrEMBL
MSIVDLGHFGHEAPRPTVSFELMPPRRPDAAPKFWETARRLVATSPDFVSVTYGAAGTDR
ETSRRVISQLLHGTPVLPIAHLTCVGASREDVEDVITDFLDAGVRSFLALRGDPPRDQPD
WRPAEDGVRSSTELVALLREVEAARCAASPSVALRGAARPLTIAVATFPDGNLAAGTSRT
QEVRRLWQKQQAGADFAITQLFYEASSYIDFVAEARAAGVTIPILAGLLPMTDPARLARV
EELTGVPAPRRVVEALEAEPDPAARHALGIRHSVELARQVLAAGAPGLHIYTFNKHQAAL
DLLEGVDLGGGAAGDASGVSSRTPDLASGPWVSGTPLPSSEPALGSASV
>A0A6N9NQ19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKIRDILAKGEPTLSFEVFPPKTEDKYEPVEQAALEIAGLKPAFMSVTYGAGGGTSRYTV
EIAAMLQAQGVTPLAHLTCVSSAREKVTSVLGELKARGIENVLALRGDIPADGQVEKDYH
YASELIAEIQKSGDFCIGAACYPEGHVESENKLQDIHYLKEKVEAGCDFVTTQMFFDNNI
LYNYLYRIREAGVTVPVVAGIMPVTNKAQIKRICAMSGTYLPSRFKAIVDRFGDNPAAMK
QAGIAYATEQIIDLIANGVNGIHVYSMNKPDVAARIRESLSEILS
>A0A399HXK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
MNFLERLHNEILVGDGAIGTMLYGKGVGLDANFEHLNLVRPSLVAELHAEYLAAGAQVIE
TNTFGANHTKLAPIGLERKIREINRRGAELARQAAAGREVFVAGSIGPLARLKGEEKELS
PAEMTAIFREQAEALAEGGIDLIQLETFSDLHQLLCAVAAAKAIGLPVVASMAFLEGGRT
GNGTDAETAARQLTAAGVDLIGANCGAGPLEILATLRRMEAATNLPLAAFANSGFPEYVE
GRYIYRTTPDYFADRAKEMVEAGACLIGGCCGTTPDHIRLLAERLSGMRPVARMVAVATD
VVESKLELSGRTEGFLARWGKEPVVTVELDPPRGLDCGKVLAGSNALKAAGADAINLAEN
PLARVRMGNIALASLIQREVGIEVIVHITCRDRNLLGLQSDLMGASLLGIRSILAVTGDP
ARLGEHAGATSVFDLNSFTLIKLLADLNAGVNGMGNPIGEGTGFTIGCAFNPNSPKMEVQ
AARLAKKVQNGAVFAQTQPLYDVDRLDEMLERTAPLGIPVLPGILPLVSERNCEYLHNEV
PGIVIPDAIRQRMRGKEKDAGVREGLAIAKEFVEAVRGRVGGFYLIPPFGKYEIAVELVK
FIKG
>D4MJR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] siraeum V10Sc8a|TrEMBL
MKIKDLYTPGRTVFSLEVFPPNKNFPIETVYDAIEGLAAINPAYISVTYGAGGNRANRST
CEIASHIKEKYGIEAMAHLTCINSTRDDVDFMLDDFAANGIENILALRGDNKPDEEPKND
FPHASDLTAYIASKGNFDIAGACYPETHVDAESAEEDIKNLKIKVDAGASHLVSQLFFDN
SCYYDFEKRARAAGIDVPIAAGIMPVTNKKQIERMVTLCGASLPSKFVKMMQKYENDPEA
LRSAGIAYAVDQIVDLISNDVQGIHLYAMNNPAVASRIYNGIKDLL
>A0A2V2LEM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meridianimarinicoccus roseus|TrEMBL
MTAPRISFEFFPPKSLDASFKLSETVRMLAPLNPGFVSVTYGAGGTTRKLTHEAVEAIHK
NYGLNVAAHLTCVDASRAETLEIAESYSNAGVTEIVALRGDPPKGAGKFTPHPEGFNNSI
ELIEALAATGKFKLRVGAYPDRHPEAASDTADVDYLKRKLDAGAHSAITQFFFGAETFFR
FRDRCAAAGITAPIIPGIVPIDNWKGVRKFAVACGTVIPPEVDEAYDKAIRDGREADLSI
AMCTELCSELMEGGVEDLHFYTLNKPHLTRDICHALGVTQTATLENVA
>A0A851Z5C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halcyon senegalensis|TrEMBL
MVNETQHTCSASSSSKSDAGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATIEVLKRLGVWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7K0JML5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrimicrobium australe|TrEMBL
MSTVPTTPPTPESDTREAVRRLVLAADYELIPLKGLDDKLGALPPATTVTVTSSVKLGLE
RTLQQSLRAAAAGYHVVPHLPARQVRDEAELRSFVGRIRDAGITDLYVIGGDAPDPLGPY
QSAAQLLAALAGIDHGLQEIGVACYPEGHPSITDEALLAALLEKQPHATYMVSQLCFDGD
AVLGWLRGIRQAGVTLPLHLGLAGPLSMLKLAELSVRIGVGASVKYLTKQHGLVGSLLRG
SSYKPEDLLLGMGEDLTAPEMGIASLHLCTFNQVEATHDWQRRIAGGGLDQR
>A0A3D1LFT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
MNEKPYTIIDRLRREVLTGDGAIGTMLYAKGVGLDSNFEHLNLVRPALVRELAGEYAAAG
AQVIETNTFGANYTKLSAIGLGHKVVEINLAGAAIARQAAAGRDILVAGSVGPLVQIKGD
DRELSRDEMEAVFRVQCNALAEGGVDLLLLETFSSLEQLQAALRAARGCGLPVSASMAFM
EGGRSADGTSVERFCGAMEAAGADIIGANCGAGPLELLKVIKRLAMLTDKPISAYANSGF
PEYRDGRYIYRATPEYFAGMAAEMAAAGANLLGGCCGTTPEHIAAIAQRIGGATPATRSR
IPHITVSEPVEETRQAASFLDHWGARKVITVELDPPKGTDCSRIIAGSRRLKQAGAGAIN
LAENPLARPRMGNIALGSVIQREVGIEVIVHVTGRDRNLIGMQSDLMGANLLGIRSILAV
TGDPATMGDHAGAKSVFDLHSFTLIKLLSDMNRGVNAIGNPIGEGTGFTIGAAFNPNTRN
MAVQAERLRRKVANGARFTQTQPIYDPAILFEALEATRDCGIPFLPGIMPLVSERNAEYL
NNEVPGITVPDAVRARMKGLEKEAGAREGLAIAKEFIDATIGAVGGYYLIPPFGKHELAE
ELIRHIKQREREQQ
>A0A317IVH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriia bacterium|TrEMBL
MTTVTSTRALEFREQLLRRVLVADGAMGTMLYSHGIFINRCFDELSLSAPDLVSRIHRSY
VDSGAEILETNTFGANRARLSAFGMADKLQAINEAGVRLAREAAQGGAFVAGAMGPLGVR
IEPLGPTSFAEAREIFREQARALLAAGADLLIFETFSDLNELREAVLAAREAAGHDPVIV
AHVTIDDFCNLPGGASPETFTREMNSWPADVIGVNCSVGPKTTLEAIERMVQVSEKPLSA
MPNAGLPARVEGRNIYLCSPEYMAQYARRLLMAGVKIVGGCCGTTPDHIKLIRSETRSVQ
PQTRRHSVTVEEPEVRAQAMTPVPMAEKSKLGAKLAQGRFAALVEILPPRGVDASREIAG
ARLCALAGIDCINVPDGPRASARMSAQVTCQLIQQHAGIEAVDHFCCRDRNLLGIQSELL
GAHAAGIRNLICITGDPPRMGIYPEATAVFDVDSIGLVHIIHNLNRGLDIGGNPMGSQTA
LLIGVGANPGALNLEEEIRRFEYKVEAGAEYVVTQPVFDLKLLENFMRRIEHVKIPVVCG
IWPLTSFRNAEFMVNELRVPVPEQFMDRMRRADSGEKARQEGVAIAREMVEHVRHMAQGV
QLSAPFGRYQLAVEVAEAIGPR
>A0A2W5QJE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Starkeya novella|TrEMBL
MSSEVERRSRRSGGKPISVSFEFFPPKTPEMEATLWNSITRLAPLAPKFVSVTYGAGGST
RERTHATVERIVKETRLAPAAHLTCVSASKDEVDEVVRGYWDAGVRHIVALRGDPPTGVG
QAYEPHPEGYRSSAELVAGIRRIANFEVSVSAYPEKHPESPSFDTDLDILAAKVEAGATR
AITQCFFDNDLYFRYLDKVRARGIDVPVVPGILPVSNFKQAKNFSSKTGTYMPEWLAARF
EGLDNDPETRKLIAAAVAAEQVFDLVDRGVTEFHFYTLNRADLVYAVCHLLGIRPPQEVS
AQGNGQAAA
>A0A1X1BZF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea conspicua|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATREELRSIAQDYWNNGIRHIVALRGD
LPPGGGKPEMYGCDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMNAMFA
GLEEDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVAAA
>A0A2G6T1C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. 56|TrEMBL
MNAAKTEATGFPVSLEFFPPKTPEGAEKLRAVRQQLYALHPEFCSVTYGAGGSTQEGTFT
TVREILAEGVSAASHFSCIGATRQSVREQLAVLKGMGVRRLVALRGDLPSGYGAGGEFQY
ASDLVTFIREETGRDFHIEVAAYPEVHPQARSPEADLKAYVAKVQAGADAAITQYFYNSD
AYFRFLEDTQKLGANIPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLEL
>A0A257HHG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium PAR1|TrEMBL
MNAFPIRSSRQVSGVPLGISFEFFPPKNDAMAENLWACVERLAPLSPRFVSVTYGAGGST
RERTHQTVKRILDETSLKPAAHLTCVAATKAETDEIIRDYWEMGVRHIVALRGDPVTGLG
TKFEAHPEGYQSSADLVAGIKAIGDFEVAVSAYPEKHPDSPNFEVELDLLQRKVDAGATR
AITQFFFDNDHYFRYLDKVRKRGISIEIVPGILPVQNFKTAASFATRCGTEVPAWLAARF
EGLDDDAETRRLVAAAVAVEQVYDLLDRGVSEFHFYTMNKADLVFAICHMLGMRAQ
>A0A5S4W6P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium cytisi|TrEMBL
MSGAMTDLTTPAGQDGHLATRRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTY
GAGGSTRERTHATISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGD
PAGGIGTPYSAHPDGYQSSDALVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKAK
VDAGATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARAFVTRAGTTVP
DWFAAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGI
RAKSAQKAA
>A0A0Q7SFI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. Root1423|TrEMBL
MTVAPRSLAEARALLLSPLGPVARAGQNSSRPRVSFEFFPPRSDEAEAGLWTAVTRLAPL
APEFVSVTYGAGGSTRERTHRTVHRILTETALTPAAHLTCVDATRGEADAVIESYRAAGV
RHIVALRGDPPGGAGIGGAYVPHTDGYANATELTAAISAKGGFDISVGCYPEGHPESPSI
SHDIEVLKAKVDAGATRAISQFFFDIDAFLRFRDRVREAGVTIPIIPGVMPVTNFTGLKR
MSAGCGAAVPDWLAAHFEGLDGDPETRKLIAASVAAETCARLQEEGFADFHFYTLNRADL
VYAICRVLGVREQKTVSA
>A0A423G6L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas brassicacearum|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASHKPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGDHFHIEIAAYPEMHPQARNFEDDLRNFVRKAHAGANSAITQYFFNADSYFY
FVERVRQLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EDVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A7C3LZW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp|TrEMBL
MFEELIDKLKGNSYLTLETTPSHEPTFDVILQKIKENNLATMVDGFSTTDNPLAKLKYNA
ILAAIKLQNEFNKPVIATMSMRDRNKIALQSDLLGANDFDIRAFLALTGDPANMSDQPRA
KGVFEGNSNMLLEIIHSFNNGMDFRGAPFKSAPKTIYPFAVTNSYAKSFKTLEKRLVKKI
KNRAVGIISQPVYDIENAKVLLNSFNNATAEFDDERNEAQLILGVFPITKLRTAQFLSSN
VPGIHVPDFWLDKFYKASKISEEEEYKVGIELSSNLIRDIKKIHPKIHLMTANKFDIAVE
LLR
>A0A3E1IQQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIANTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VSYIRSKRPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTYLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNAECLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A2C5ZVM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps australis|TrEMBL
MHIGSMVAEAGKGHQPSFSFEYFPPKTAQGVQNLYDRIDRMYNLGPKFIDITWGAGGRIA
ELTCEMVTQAQSVYGLETCMHLTCTDMGLERVNDALRKAYKAGCTNILALRGDPPRDQEK
WTATDKRFQYASDLVKHIRDTYGNHFDIGVAGYPEGCDDNKNEDVLLDHLKQKVDVGATF
IVTQMFYDADNFLRWVAKVRQRGISVPIIPGIMPIATYASFLRRANHMQCKIPQAWMDAL
EPFKNDDVAVREIGKTLVADMCRKLLANGICHLHFYTMNLAQATRMLLEELSWAPCAERP
LRHALPWKKSKGLGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRSKWGEPRSIRDIANTFVRYLEQEIDSLPWSESPLTGETDSIKHHLVA
LNKRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPREILTEMLRRIESRP
SLTYYAVTSTGELESNVDSDGPNAVTWGVFPGKEIVQPTIVEGVSFLAWRDEAFRLGKDW
AHCYDSNTPSRALIDSIMDGWYLVNVVNNDFRENFAIFELFKDLEVKDLDVCQGVPK
>A0A2M8BW50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG_4_9_14_3_um_filter_45_9|TrEMBL
MISKFRQVLNSGKFVVTSEIGPPKGTNIEKMLHHIDLLKDKVDALNVTDHQSSVMRFPSI
GGCLAIKEQGGEPILQMTCRDRNRLALQAELLLAYTRGIRNVLCLTGDAIPVGDHKEAKG
VFDLDSVQLLRAIRQMEAGKDLGGNELDGTIEFCAGAIVTPEARPIEPQLIKFEKKVEAG
AEFFQTQAVYDLDNFAKFMQYARQFSVKILAGIVLLSSASMAKYMTENVPGIFVPKYLID
ELASAPRGEALNKGKEIAGRMVATLKKESICDGVHIMAIRREEVVPDILAIAGL
>A0A432TSD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thioglobus sp|TrEMBL
MKTSFEFFPPRTDKGKQTLAQVRQELSTINPEYFSVTFGAGGSTQDATLETVLDIQANDS
VSVAPHLSCIDSEKAKIIELLDQYKAADINRLVALRGDIPSGVRDIGDFHYANELVEFIK
SEYNDHFHIEVAAYPEMHPQAKNIQTDLEHFANKVKAGADAAITQYFYNADAYFRFRDDA
QKLGIDVPITPGIMPITNHAQLLRFSNMCGAEIPKWILERLKLYENDLTSLTLFGTEVVS
NLCQTLKDQGVDSFHFYSMNRTEPSLSIAKHLL
>W7M3W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella moniliformis (strain M3125 / FGSC 7600)|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIESHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKNLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A3E2CH86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
FLHFRDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKISEPVLAMIERWGSNPEVLQ
DAGSIFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A0D9S8L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorocebus sabaeus|TrEMBL
MDHRKARVLPAGHYCPSLGIWASQAGSVRFSVPPSISRNLAMVNEARGNGSLSPCLEGSA
SSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRNEFGDYFDLCVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIERWGKLYEESSPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDTLELLNRPTQNERETEAP
>A0A7N8Y5Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mastacembelus armatus|TrEMBL
MVNQVQRDGGSWQSCKSDSSGASNSGGESSKESSRCSTPVLDADRADRLRDKMRRRMDSG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPSGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPMGTDWEEEEGGFNYAV
DLVKHIRSEFDDYFDICVAGYPTGHPEAQSYEQDLRHLKEKVDAGADFIITQLFFRADTF
LKFLDDCRANGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIHQAVEICRVLLDSGKVPGLHFYTLNREVATIEVLRQLGLWKEDPRRPLPWAISAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLQMWGKELMNEDSVYEVFTCYITGQPNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSADPIVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRV
NYHIVNVHGRNLTNAPDLQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLQTAPRCNHSTKARPQDGA
>A0A1Q6MVR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprobacillus sp. CAG:235_29_27|TrEMBL
MKINELLKKRPTLSFEIFPPKNNENDITSIYATIDELAKMNPDFISVTYGANGSTSKNTC
KIASTIKNKYGIESVAHLTCMNNTKDEIKEILEELKENGIENVLSLRGDYPKDGDGINHG
DFKYASELNEFIEENFPNDFCLSGGCYPETHYEAKNFEEDLLNLKKKVDAGAKYLVTQIF
YDNQYYYRLVREARKIGIHAPILAGIMPAHNPKQLKNIAKMSNCSVPFDLAAMIDRFAGN
PKAGREVGLHYATYQIIDLMTHGVDGIHIYTMNKPEIAKEILKRTEYIRDEFFKD
>A0A1Q7KQ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_40CM_4_58_4|TrEMBL
IIETNTFGANRFKLMPLGLGDEVQRLNSRGVKIAREARESAAREVLIAGSIGPLGLGVQS
RHPADDEILDIFHEQALALEERGVDFYILETFSYIEELLLAIDAIRSFSGLPIVAELTYA
EEGTTYGDVRPSNAAAQLKNKNVQVIGANCTLGPQALLPILQELAAVDDIRVSAMPNAGF
PKREGDRIVYPRSSPEYFALFAREAAALGVRILGGCCGTTPAHIRAMAEAVKLLHPAKSH
AVASPVEAVPKPAPVTQREPESQFWENLKAKKFTVCVEIDPPKGLSLDRIFEQVDKVMGS
KKVDAIDINSGAMARVGMDALIVAGALEARGVETVPHLTTRDQNIIGLQAALLGAWTVGG
VRNILAITGDPPSVGDYPETSGVYEVDSVGLVKVLHRLNQGTDWAGKTLGGATNFTIGVA
LNPVADDLDNEIDRFHAKVEAGAHFAMTQPLFDPEHWHAFLEKLGGKPSIPVLIGIWPLN
SYKQALRLNNEVPGIVIPEPLLKSMESAGADARDRGFEVARKMLAWARTELAGAYLIPPF
KRYEEILEIL
>A0A2U0A723|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium symbiont of Ctena orbiculata|TrEMBL
MHTEHQKRNISFELFPPKTEKGFENLKHSVAELKAEQPAYFSVTYGAGGSTQKRTFDTVN
WLMDEQITTAPHLSCIGASREEILEILEYYKSIGISRLVALRGDLPSGTGLGDLGDLSHA
NQLVALIQETYPQQFHIEVAAYPEFHPQASSPQQDLSNFKLKVEAGADSAITQFFYNADA
YFRFLDNCQQLQIDIPIVPGIMPITNFTQLARFSDACGTEIPRWLRKRLEGFGDDLEAIR
GYGKDVVISLCERLLAGGAPGLHFYTMNQSKPTLDIWQAL
>A0A0Q8QE75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Root710|TrEMBL
MTRVSLNQLEEARRALDTPLFADLAGDAAVSFEFFPPKSDKMEETLWSAIQTLAPLKPRF
VSVTYGAGGSTRERTHHTVARIATETAIPAAAHLTCVEASKAEIEEIARAYWAAGVRHIV
ALRGDPPTEGATFAPHPDGYRNAAELVAGLKAIHPFEISVAAYPECHPEAASIEADIANL
RAKFDAGATRAITQFFFTPEAYFRFCDRARAAGIEGEIVPGILPVSNVAQTRKFAGMCGA
AIPAWMDRLFEGLDDHPATRQLVAATIAAEMCRRLYAGGVRQFHFYTLNRAELSFAICHL
LGLRADAKALENAA
>A0A285UM39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium subbaraonis|TrEMBL
MAHIDENPLGPHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGV
GPMASAKTARWIRTNVPGIHIPDSIISRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGVLKGRKPWTREPNPVDSLVAERLEEARVGKEQNQQEMAEIAA
HHPH
>A0A0D0QCN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. A03|TrEMBL
MTAISFEFYPPKTDDQRTQLDRTAARLKAAAPDYVSVTFGAGGSTLSHTPETIERLQRHH
ALEAAPHISCIGGSRAEIRGQLERYMSMGAKRLVTLRGDLPSGMASPGDLRYASDLVEFI
RAETGDHFRIEVAAYPEMHPQARDAHADLKHFIGKAKAGADGAITQYFYNADAYFRFVDD
VRAAGVGIPIVPGIMPISNFSQLRRFSEMCGAEIPRWITQRMLAYGDDVASVRAFGADVV
AQLCQRLIDGGAPGMHFYTLNLAKPTLAVLARLDGQRSGVTA
>R5AH52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:1024|TrEMBL
MRIPEIFEKRAAFSFEVFPPKTDVGMEKLCGDGGVLDKLYTLHPDYISCTYGAGGTNVGK
NLEVLDKIHKDGKAIPVTHFTCIGNTKEGIKDQLENYLAHGIDHMLALRGDLPFGWEGTG
GDLHYATELVKFVRKEFGSKFTIAVAGSPEGHISCRSLESDIGFLKQKQDEGADYIMTQL
CWDMDQFRYWLDAIRGAGITMPVDVGIMPILDQAATINMALSRNGCVMPRELCEIISKNW
IFPNPFVKDPFDANVEEKKASFKEAGIEYTIRQIDEYRACGIDGIHLYALNKYDDVARIV
KESGIVDLI
>A0A139TWG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia sp. KLE1798|TrEMBL
MHLKERLQSDAGPTLSFEFFPPKNEQAAAALYQTIRELEPYRPSFVSVTYGAGGSTRELT
REVVLRIQNESRIPTVPHLTCVGHSREEIWNILDRYAQAGVRAVLALRGDPPRGVEHYDR
SADAFRYAVDLVACIREYNESGRHPDPDGFAIGVAGFPEGHPSTPNRLREMDFLKAKVDA
GADYICTQLFFDNHCFLDYRERCLLAGIKVPVLAGIMPVTSLSGMNRMAELSGGTCFPAR
LLKALKRAGGNAEAIQEVGIQYASSQCAELLDAGVDGIHFYTLNQSRATRQIYRNLGLRD
SLQLLEHGEDK
>A0A3R7Q3N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium TMED162|TrEMBL
MTGISFEFFPPKSEAAGEKLWQAIDRLAPLSPDFVSVTYGAGGSTRDRTHACVKRMIDET
TLKPAAHLTCVAASKAEVESVIDDYAAAGVRHVVALRGDMPDMAAFKAHDDGYSGSVELV
EALAKRGGFDITVSAYPEKHPESASLDADIDLLKAKIDAGATRAITQFVFDTQAHLRFRD
KLAAAGITIPVIAGIMPTTNFAGAKRMAEACGAAVPQWLADAYEGLDEDLDTRKQIAASV
AIDQCRKLIDEGFGHLHFYTLNQADLTFAVCRILRLGAAAN
>A0A844IW34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dolichospermum sp. UHCC 0260|TrEMBL
MPDTHSLSAFNNFRKAALAGEFLITAEVAPPKGGDPVQMLAMAATLKGRVHAVNITDGSR
AVMRMSSLVASVILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPQAKAVFDLEAVRLLQLIRNMNRGVDFNEKPLTDGALDLFAGAAVDPQSQSWSGLQS
RFEKKIVAGAQFFQSQLITDFEILEKFMDKIAVGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEEGMKIAAEQVQIARGLCQGVHLMAVKREDLIAPILDLAGV
EKVS
>A0A8H9M4N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis bartoniae|TrEMBL
MTLSQETPRARRAGLAELVRTMSYEVMPFKNTERDVLEYVPTSVPLTVTVTEAKGIGTTL
DLTERLLRHGYTVAPHLPARQFTDEAHVADVVARLTEAGVRSVFVVGGDAPEPAGRFDDA
YSLLRAMAEIGHPFDEVGIGGYPEGHPKIPRETLDLALKQKAPLATRLLTQICFDANTTA
DWAAGLAADGLTLPVYVGMPGPVNRQKLMRISAGIGLGQSARFLQKQQSLLWRFLLPGGY
DPTKLARRLGAAAARSDGNIRGLHIFTFNELRGTEEWRQRLLAALAGKDRS
>A0A8B6UPW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas corrugata|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRTLLARYKAAGIQRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVNKANAGANSAITQYFFNADSYFY
FVERVRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQRFG
EDVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A417PN97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium OM08-6BH|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVEELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAGI
>A0A561VYK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora taraxaci|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTDAGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATDTTLLPMAHLTAVDHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWIRHPEGVDYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAQFVR
KCRAGAAFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGVEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARV
>A0A167Q5D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC 33097 / NRRL 1555)|TrEMBL
MKVIDKIKRAEEEGRVYWSFEYFPPKTTQGVQNLYDRIERMQKFGPEFIDVTWGAGGTTS
DLTTDIVQTAQTVYGIETMMHLTCTNMPVEKIDAALEKAKKCGCQNILALRGDPPHGQET
WKSCEGGFNNAIDLVKYIRLKYGDYFGIAVAGHPEKHADCPTLDQDILHLKAKVDAGADL
VVTQLFFDVDIFLSFVEKCRAAGITCPILPGVFPIQNYNGLKRVISFNDNHVPQAIWDAL
EPIKDDDAAVKEYGIQLTVEFIQKMLAAGLNGVHFYTFNLERSTRLVLERLNYVASQETV
KPLPWKPSLHTKRIKENVRPIFWKNRTMSYIKRTELWDEFPNGRWGDSRSPAFGELDGYG
ISLKHTPAECLKMWNSPTTIQDISQIFSSYCAGKVAALPWCFHELDPESEKIRSHLAALN
NLGYLTINSQPAVNGVKSADKVHGWGPKNGYIYQKAYLECFLSPEKLNDLVTKIGSNISI
TYYAVNQQGDLRTNTQSDGPNAVTWGVFPSKEIIQPTVVEAAAFMAWKEEAFALWHEWAR
LYDAESVSNKLLKGVADNWYLVNIVHNDFQDSDGIWRLFDIESAVEPTQQAMR
>E0PPW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis ATCC 6249|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A0H3KIB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia multivorans (strain ATCC 17616 / 249)|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLDAAPHLSCIGSSRDSLRAILDQYRSCGIRHIVALRGDLPSGMGSVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATKAICERLDV
>A0A2K8T517|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc flagelliforme CCNUN1|TrEMBL
MKILNFMHHTHSPTAFQRAVQAGEFLVTAEVAPPKGGDPAHMIQMAATLKGRVHAVNVTD
GSRAVLRMSSLMASVILSQNGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALTGDP
VKAGDHPDAKAVFDLEAVRLLQLIRKMNQGVDCNEKPLTDGALDLFVGAAVDPQCKSWSG
LQSRFERKIEAGAQFFQSQLITDFERLEKFMDTIAAGYKKPILAGIFLLKSAKNAQFINR
CVPGVNIPQHIIDRLAKAKDPFEEGMKIAAEQVQIARQLCQGVHMMAVKREDAIAPILDL
AGVAPVNQLVSK
>A0A838W5L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MPDFRDLLLDGRPHVFDGAMGTMLYARGVYINRCYDEMNLREPDLVREVHRAYVRAGAEV
LETNSYGANRVKLARHGLETELEAINARAAEIARSAAGDGVFVGGAIGPLGVRIEPYGPT
STAEARELFREQAQGLLTGGVDLFVLETFSDLIEIQQAILAVRDVCSLPIVAQMVIREDG
HTVLGTDVALCAERLAEWGAEVVGMNCSVGPHAMLPVVERLAPGLGRPLSVQPNAGLPRE
VDGRKIYMASPEYMAKYASRLIRKGARFVGGCCGTTPEHIARIADAVRAVAPRAQTVAVS
APEPKTSPREPVPLVERSRWGAKLARGEFVTTVEIVPPRGTDPEPMLAGVRLLKEAGVDG
VNVPDGPRAQSRMGVLATSLLIQQQVGIEPVIHYCCRDRNLLGMLSDLLGAQALGLRNLL
LITGDPPKMGPYPDATAVFDIDAIGLTNLVSRLNRGLDPGGSAIGEPTSFTIGVGVNPGA
VDFEHELKRFYWKVDAGAEYAITQPVFDVAQLLHFIERIEREGIRIPIIAGIWPLVSARN
AEFLANEVPGVVLPDRVLQRMQRASAIGKEHATEEGIRIAQEMLAEARPAIQGVQVSAPF
GKVSLALRVFEALPGASGTEAVRAAIA
>A0A8I1MHN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia flexa|TrEMBL
MGLLEDLQSRILIGDGATGTLLYSHGIDSCFEELNITKKEEIQRIHRAYVEAGADVIQTN
TYAANYQKLARYGLEDAVKDINISAVRIAKQTAKKDAYVVGTLGGIRSFQKNAISTEEVK
RSIREQLFWLLNEGVDGLLFETYYDFEELKTVLSLARKETSKPIITHVSLHDIGVLQNGT
SLYDAFQELESLGADVVGLNCRLGPSHMIQSLEEVPLLDRAFLSAYPNASLPAYVEGKVE
YATNQDYFVESAKAFRNQGVRLVGGCCGTTPAHVQAMSQALKHEKPITQKKVKIRPVVEI
KEQEQTKEPHLHDLVKERRSIIVELDPPKQLGPTKFLDGAKALHKAGVDAVTLADNSLAS
PRVSNLAMASLMQQQTDARPLVHITCRDRNLIGLQSHLMGLHTLGINQVLAITGDPSKIG
DFPGATSVYDVSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVVRL
EKKISCGAHYFITQPLYSTKQIEEVYEATKHLDAPIYIGIMPLTSARNARFIHHEVPGIK
LSEDILARMDATGEDRIKGEVEGLAIAKDLIDTAYELFNGIYLITPFLRYEMTEILTRYI
NDKQLVTTERKN
>A0A3M2BNT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MPAEDRSPLRALIDDGRVHVLDGAMGTLLYERGVFVNVCYDELVLSEPDLVAGVHRDYVD
AGAEIVETNTFGANPVKLAAFGLDERTEEINRTAASLAREAVGGRALVVGAVGPLGIRIE
PFGPTSREEARALFERQVAGLVEGGVDGFVLETFSDLTELEQAFCAVRAHSEAPVFCLIT
VGQDGRTQYGTGPEAVAAEATRWGADVIGVNCSVGPAVLLDAVEQMARVTDRPLAAQPNA
GLPRDVGGRTLYLASPEYMARYARRMIEAGARFVGGCCGTTPEHIRRIADAVASVQPRLD
AAAVRVAARAAEPAEAEPLPLAERSAWGRGLAEGRRLRALELMPPRGWDARPLLEAASRA
KDAGADAVTVLDSPRAQARMGALPAALIVEREVGIETVVHYTCRDRNMLSMISDLLGAAA
GGVRNLLILTGDPPAAGPYPDATAVFDIDSIGLTNVVAALNRGRAPG
>A0A7K4EP24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteria archaeon|TrEMBL
MNSKNGIFSFEFFPPKTAEGIEKLRATQAELAKVEPRFFSVTFGAGGSTRDRTAETVFDI
QTKSGIETAPHISCISSTRENISEMLTHYRERDISHIVALRGDMPSGMVEAGEFRYANEL
VAFIRETTGDHFHIEVAAYPEYHPQATSPDRDLANFRRKVEAGANSAITQYFYNADAYFR
FIERCGKNGIDIPIVPGIMPITNYFQLARFSDACGAEIPRWIRKPLEIYGEDIDSIRAFG
EEVVTGLCERLLQHGAPGLHFYTLNRSAPALAIWNNLGLSDL
>A0A7V5T604|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MALLGRLRAKADAGEKTFTVEISPPVNYKTMVKTDEMVRALKDFDIAGIAVTNSTGGSFR
MNPLAVVETIRAWRPETPIVIHLTARDEGSVRSIYSRADEMDRKAVSDVLVLRGDPTPQR
SRQVDAFKFSTVELVRLLREYRDGQGYAIDIFVAGHPEYPAHALSKHMAYQRRKIEAGAQ
GIIANIITDPTNYARYVDAALAHGIAVPILPSVIPLTSVRRCIFLQTGLHIPVPRWIMER
LDEAGSKEEAARLGLEITIGIVERLLYEGAPGVNFNLIFPQDIASVADILRTVRGHATIW
EKYKIEDPEEIEYYSQLRGRLS
>A0A2V7IF47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYSKGFFLNVCYDELNLKQPKLVQEVHEAYVRAGAEILETNTFGANPAKLASYGLA
AETERINQAAAELARKAAAGRASVVGAIGPLGLRIEPFGPTSREEAFAFFQRQAKGLLAG
GVDGFILETFSDVDELHEGLRAVRSLSDLPVIAQMTIGDDGLTHYGTAPEIFTKQLAEWG
ADVIGVNCSVGPAGVLEAVEKMVKVTDRPISAVPNAGLPKDVGDRKIYLASPEYMASYAR
RMIEAGARIVGGCCGTTPEHIKKIRDYVASVVPRHQPVVVSRDVVAAPAGVEAVPLAERS
RFGTKLARRELVTSVEIVPPKGVDPAPMFAQCRALKAAGVDAVNVPDGPRAQSRMGALLS
SVIIEREVGIETVTHYSCRDRNLLGMLSDVLGASAAGLRNILIITGDPPKMGPYPDATAV
FDIDAIGLTNLVYRLNHGLDPGGNPIGKPTQFAIGVGVNPAATDLDRELSRFAWKVDAGA
DFAVTQPVFDIAQLESFLNRVEQFHIPIVAGIWPLLSLRNAEFLANEVPGVSVPDTVLAR
MRKASDGGKDSALAEGVKIAREMFALVKRDVQGIQVSAPFGKVEVALEVFK
>A0A8J4KGJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eudyptes chrysocome|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAIDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWTEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A2T3INK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium aquimaris|TrEMBL
MVNLDQTTQTESELRVRYNDITRGVYFIGTTPPKTSTPLEEVEGIADRLVNRIKDLAIDG
LIVYDIQDEVSRTQKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSETDAFDEWL
NEAWHEYQVRDIVLVGSPSAKNEVSLPLSAAYQTLAENNNNFFTGGIMIAERHAKKGNEH
ARLIEKYQQGCNFFISQAIYDTQATIDILTRYAIECKQDGIKPQRILLTFSPCGSAKTLE
FIEWLGVSVPEATSLRILNASNPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRK
EEIDGSILLYKLLRASMDSHLAKHEFRTLQRNKLISV
>A0A2G4FTF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MSATEHPTNTPDTANGATSPRPRAELLARLLDPEQVIMFDGAMGTMLYARGVFINQCYDE
LVLRSPDLVREIHAAYVKAGAEVLETNTFGANRAKLTQYGLEGQVSAINTKAAQLAREAA
GEYRLVSGAVGPLGVRLEPYGPTGKDEARGLFREQMLALKAGGADCFLLETFTDLEELEQ
AILAAREVDAGMPVIAQATVGPDVRTAFGASPEDIARVLDRWGVDVIGLNCSVGPQTILE
AIERMATVTTRKLSAQPNAGMPRDVGGRSMYMASPEYMATYARHLIQAGAKIVGGCCGTT
PDHIKAMVEGVRPLAPRTRVIVEHDRSDAMHDEPVGRAPVPLAQRSRFGAKIASGQFVTS
VEIVPPRGVDTVKLELDAAALHKAGVDAINVPDGPRAQSRMGAIATSLIIERHGIEAVTH
YCCRDRNLLGMLSDLLGASALGLRNMLLITGDPPKMGPYPDATAVFDIDAIGLTNLVNKL
NRGLDPGNNPIGEPTRFVVGVGVNPAAIDPAHELKRFHWKVEAGAEYAITQPVFDPAQLE
HFLTSIDDVRIPIVAGIWPLVSARNAEFLANEVPGVTVPKEVLDRMRKANDKSKEHALAE
GIAIAREALERVRGSVQGVQVSAPFGRIELALEVFG
>A0A7W1C7C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MRFPSRPPAPRGAEFLERLRENVLVADGAMGTEIYEHGVFINQSFDVLCLTRPELILEIH
RAYLAAGADLLETNTFGANRARLLGHGLEERVVDINRAGVALAREVATGAAFVGGSIGPV
GVKGQVAGDYSPGDLQAIFAEQAAALLEAGVDVFVIETIPALAEMTAALEAVRGLDSSVP
IVALMTFNDDGQTQAGDTPEEVVSHLARAGADVVGANCSVGPKPMLDCLMRMHVGAGLPL
AAMPNAGLPQSVEGRLMYMASPEYFGKYAKRFVQAGVRLLGGCCGTTPSHVRQIKLAVSG
IVPGVSQGTGFEIDGPAPLAAIEPARTGRKSDLALRLERGEFVTSIELTPPVSADLSALV
EAVHDIQAAGVDAVNIPEYARISPRVTPLAIARVIREEVPIETIIHYCCRDRNLYGMQAD
LMAAHALDVRNILVITGDPPKAGEYAVPTAVFDVDSIGLVRVVSGLNRGLDAAGKETGVP
LDLHVGVGFNPGAIDRGRELERFRRKVAAGAEFAMSQPVFDVRHLETFLAELGDQTIPIL
VGILPLYSHRNAEFLHNEIPGMSIPAGVRERMRGVTSQATAMAEGVKIAREALEAARSLP
AVRGAYLMPPFGRHALALEVLDGLHGPS
>A0A7Z8P1Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanolobus vulcani|TrEMBL
MSRTFKDKLSSNDFLITAEVSPPKGTDLIDVLSDAELIRGWVDALNVTDNQKAIMRMSPL
AVSKSLLDSGHEVIMQLTCRDRNRLALQSDLLGAYSMGIRNICIMTGDHTTKGDHPKARP
VYDLDSVQLLKIVRKMQEGFDLAGNVIENPPQFVVGAVTNTDPSKKAQMMKLRKKVKTGI
NFMQTQAVYDISMFESFMESIGDIEVPIIAGVIPLRSANMARFMNGNIPGINVPDEIIER
MESAEKPKDEGMDICAETIKELKKLCRGIHLMPIGKHNNTPTILEMADIRKKQ
>I2IEL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Ch1-1|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLATLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRQDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCGRLIDAKVPGLHFYTLNGAAATKAICERLNT
>A0A2A2N1B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. V1B|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDATRDELIDIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A0F0CFR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. FS41|TrEMBL
MKIRDILAQGRPTLSFEVFPPKTEDAYDTVERAAAKIATLKPDFMSVTYGAGGGTSDYTV
GIASDIQKSGVTPLAHLTCVSSTRDKVHSVLEELKNHGIENVLALRGDIPADGRTPREYH
YASELIHEIKQSGDFCIGAACYPEGHVESANKSVDMDYLKEKVEAGCDFVTTQMFFDNSI
LYSYLYRIREKGITVPVIAGIMPVTSAKQIKRITQMSGTYLPSRFLAIVDKFGDNPAAMK
QAGIAYATDQIIDLIANGVRGIHVYSMNKPDVAMKIRENLSEIL
>A0A2E0YWJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halioglobus sp|TrEMBL
MARETPRISFEFFPPKTPGGTDKLLNEVRPALSELEPEFFSVTYGAGGSTRDTTLGVVSA
IREKDIAVAPHLSFGGSDDEAVAQLLQRYRDIGVRRIVALRGDRPSGMGGATLVYANELV
QFIRERTGDHFHLEVAAYPEIHPEAKDYDSDVRFLKGKFDAGADSAITQFFYNVESYFYF
LDQCAAAGIDKPVYAGIMPLANYANIRRFAGNTGAEIPRWICQRMDGFGDDVDSQVKFGT
EVVTQLCQTLLENGCPGIHFYTMNQVEPTREIYHNLGLRQ
>A0A1T4MI37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sediminibacterium ginsengisoli|TrEMBL
MKITEHIRQSKDTLISFEVLPPLKGKTITSLYDHLDPLMEFKPSWINVTYHRSETMFKKK
ADGTFEKVEVRKRPGTVGICAAIMNHYKVDAVPHIICGGFTKRETEDALIDLDFLGIDNV
LVLRGDAAKNETSFEPEKDGNHYALDLLQQVGNMNNGIYMDEDIKNGGKTNFCMGVAGYP
EKHFEAPNLEIDLLKLKQKVDAGAEYIMTQMFFNNQKFYDFVKACRDMDIQVPIIPGLKP
VTNKKQLTVLPRTFHVDIPTELSNAIMKCKTDAECEQVGTEWLVQQSKELKAFGVPVLHY
YTLGKPKVIWNVVKEIV
>A0A255PPB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. FBKL.4005|TrEMBL
MALGTASTRTDRARTVRDILATGKPTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVAHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWETDVAHFVD
KCRAGADYAITQMFFRPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPKLSNAHV
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A1A2P5Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. E1715|TrEMBL
MMSAGLGCPKRMVFGPCGGVRPDGQCEMRPGPCAFDEVVAWSGPQSTPRLAHAPLVLTDF
SSTPFDRDDIAATAAALAQGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDR
NRVVLEQELRGLLGIGVETVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASTGVVAAV
PETPTAPPAHARPARLVEKQRAGASLAVLNHVPSAGQVADFMAEARAAGLTIPVIAAVAV
FTDSASAAVLQGLPGLELDQDVTERVLGAPDPVAEGIEAAVAEARALLSIEGVEGVNVSG
LASASGPRAGAEIKGEVGRRIRAEARR
>A0A0D5NPZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus beijingensis|TrEMBL
MTLLLEKRQQQQDSFAVTAELIPPRDWNPRPLIEQALRYRGYVDAVDLSDNLLAIARLSP
VVGAFFVRQVGMEPIVQINLRDRNRMGIQSDLMGLAAIGVKNITILGGYPAKVGTEPSAK
EVYDLETMELVRYARKFADEGLLFDGTRMQEPPKFTIGTVENIAGKPIKELIDRLETKVD
NGTDFVRTQLVFDMDLIGEWMEEARRRGLHERATIMASILPLRDADHVGTALKIPGIVIP
DSFRGRLAASESKEEGLVIAAELIKQLRQIEGIKGIHIRPIGGAEDSVNKVVQYAGLLSS
PKIPASA
>A0A3D2UFS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
NPVPLEQRSAWGRKLARGEQVASVEIIPPHSWDASAVTSPARELKVSGVDAVSIVESPRS
RSRMGALSAALIVEREVGIETIVHYTCRDKNMLGMISDLLGAAAAGIRNVLVVSGDPPVM
GPYPDTTVVFDIDSIGLTNVVQGLNQGIDPGGNTIGAPTEFVQGVAINHGSVDQERERSR
FEYKVDAGANFATTQPVFSPKALEQFLDATTPEIPIVAGIWPLTTLRNAEFLANEVPGVH
VPTELVDRMRRAHLSGADAALEEGVAIALELINATQDFVQGFHLTAPNRKVQVALRVLRE
SGILATA
>A0A137S8P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter excellens LAMA 842|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRAEIGELLDLYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISDREKIAF
>Q0RNS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia alni (strain ACN14a)|TrEMBL
MGEFLASGRPSFSFEFFPPRTPEGERHLWTALRRIEALRPSFVSVTYGAGGSTREGTIRV
TERIATDTTLTPIAHLTAVNHSVAELRQVIGNYAGAGVRNVIALRGDPPGDPQGTWTAHP
QGLEHADELVRLVKSVGDFCVGVAAFPDRHPRSPDFDTDARYLVGKFDAGADYAITQFFF
GADDYFRLVERVRALGCDKPIIPGIMPVTNVAQIVRMAQLSGAAFPPALAARLQAVADDP
AAVRAVGLEVATELSRRLLDGGAPGLHFITLNRSSATREIFEAVR
>A0A0C1IXJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavihumibacter solisilvae|TrEMBL
MKVIDHINGAKETLISFEILPPLKGKGISAIYNHLDPLMEFKPSFINVTYHRSETMFKKQ
ADGSFAKIEVRKRPGTVGICAAIMQHYNVDPVPHLICGGFTKEETENALIDLAFLGIDNV
LVLRGDAAKNETFFEPESGGNRYAIDLLKQVLDLNNGIYLEEEVKNHGNAKFCIGVAGYP
EKHFEAPNKATDIAYLKAKVDAGAEYIVTQMFFDNQKYFEFVDSCRAAGINVPILPGLKP
ITSKKQMSILPRIFHVDLPTDLSNEIMKCKEDADVEIVGTEWLLQQSRELKKAGVPVLHY
YTLGKPKVIWNVVKELV
>A0A6I3I9M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. zg-86|TrEMBL
MVHTPSLSFEVFPPNPAAGNEKILSALQDMQGLAPHFISVTASNNTFNIEETTVRLTDYI
QNDLGIPSIAHLPAIYLTKKQVTTILAALDQIGVHKILALRGDILPDVTPQKDFQYATDL
ISFIKEEAPHFDIIGACYPEVHPDSPNQLSDIKHLKKKVDAGCSTLVTQLFFDNDVFYDF
QEKCHLADIDVPILAGIMPIINRNQALRLLNTCENIRLPRKFRAILDKYEHDPESLKAAG
LAYAIDQIVDLVTHDVAGIHLYTMNNPYVAKHIYRATYSLFKHSPLIAKA
>A0A4V1UMS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MRFAYDSVGLGSRRESVIHNRSVSLQQALQSGVLLGDGANGTFLSERGFVGEHFDLANLL
APDLVREVHAAYFEAGSDFVETNTFHATRLILGGDKLDVDGLCREGARLAREAAGPGRYV
VGAIGPAGKPIEPIGSITRAEIVAAATRQTKALLEGGVDGFMLETFVDVEEMKAAIEGVR
AVSDLPILASKAYIEDGEMLAEGLPGRCSSELALTGIQAVGANCIVGPQRMLDLVRQMVE
TTELPVIAFPTPGLPQLVKGQVVYDTDPDYFAKASLRLIEEGATVLGGCCGTTPAHIRAL
RTLLAAKPPKPRPRTGGVKERTEKKPLPTTPPSELAQKIGKEFITAVEMDVPRGLNLDKL
LSGAKALKEAGADVINISDGARARLRMNPAAVSHTIQSQVGIEVTMHFACRDRNLLAIQS
DLLGCHALGLRNILAVTGDPANIGDYPSATSVFDIDAIGLVRILKRFNEGIDLAGYSVGV
QCGFTIACAYNPIPMDRSLELDRLKRKAEAGAQLVYTQPVFDVADAERAAEDCAALGLPV
LIGVLPLKTGRHAEFMHNEVPGIRVPEALRARMASAADDETALAIGVEEAQKLTAAIQAC
AQGLYLMPPFGSAAIAARVMAALSDANR
>A0A7X8D7C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MSAKAILSAEFFPPRDIAAQEKLVRSAKSLMGLNLSYVSVTFGAGGSTRSGTADAVQLLQ
NLGFDVAPHLSCIGASKADIAEILDSYQQKGVKRLVALRGDLPSGMGGDVGELRYASDLV
AFIREHSGDAFHIEVAAYPEMHPQALSFEEDVRHFVHKVNQGADAAITQYFYSAGAYFDF
VERVQKAGVTIPIIPGIMPITNSSQLLRFSNMCGAEIPRWIRLRLADFGDDRASIRSFGL
DVVSQLAQDLIDGGAPGLHFYTLNGAEATMNIVNRLSL
>A0A522BEP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MSETYSKFQESLLDKNTFSVTWELVPGRGSFEAAQDVVMASAAAAAKGGKVHALTITDNP
GGNPAISAEMLGAEIMKLGIEPLVHFTCKDKNRNQLESLLYGMERANVRNLLVMTGDFTY
SGYQGRSKPVFDMDASQLVGMTTALNKGLTVPTPKGSTTIKPTHFFAGAAVSPFKALESE
QMGQYYKLKKKLEQGAQFIVTQLGYDIRKIHEALQMVKHLGFGDVPVVGNIYLLPLGAAR
LMNRNGLPGCVVTNELVSVLAKEAEAEDKGKSKRIERASKMYAFMKGMGFAGVHIGGHGM
KYEEVEMIIQRGEELAPNWMDLVGEFNFPQPNGWYYFEKDSKTGLNTDKPVDRSKRPSSS
LGYKAFRVLHHSMFEKSGFLFSPMRAFAKAIDGSALEHPFTRVEHLMKVITNECMHCGDC
ALFDTAYVCPTSQCPKSQRNGPCGGSYNGWCEIYEGKKQCIYVRAYPRLKSHGAEDTLGA
YYVPPINFDLLWTSSWLNFYMGRDHTAKRLGVLPPEKK
>A0A850KY65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kangiellaceae bacterium|TrEMBL
MSALIQSYEHLEHIESINQKFSELDGKVNVSFEFFPPNSDQMHKTLWDTVKRLETLQPDF
VSVTYGAAASTRERTHQVIDRILSETSLTPVPHLTCIDATEGEIETIANNYWDKGIRHIV
ALRGDVEEQQITGEFKYAVNLIEKLKQLHNFEITVAAYPEVHPEAPDANFDLDNLKRKID
AGATRAISQFFFNTEVFLRFRDRCIAQGIDIEITPGILPVTNFEQLVKFSKFTNVAIPTW
MEKLYQGLEGDPTTRKLIASHLAIEQVKHLSKEGINNFHFYTLNRAELTYAICHSLGKRQ
QLQINRKTA
>A0A2K3YNV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus rostri|TrEMBL
MSRLLNTLKHKVLVADGAMGTILYSDGLDTCPEAYNLTHPEKVEHIHRSYIEAGADIIQT
NTYGANFEKLKQFGLEHKVKAIHEAAVAIAKRAANEDTFILGTVGGFRGVKKGDLSLSAI
LYHTEIQVDTLVTAGVDGLLFETYYDLEELLKVITATRARFSDIPIVAQLTASNTNYLID
GTEINDALQQVTAAGANIVGLNCHHGPMHMKNSFSHIALPDKAYLSCYPNASLLDIDNDT
FKYSNNAQYFGDTAEQLIQEGVRLIGGCCGTTPEHIRHIKASVASLKPITEKKVIPIHKQ
REKRKQGTQRLTLSERVRQRPTIIVELDTPKHLDTTRFFDNIKALDDAQIDAVTLADNSL
ATVRVSNIAAASLIKQRFNIEPLVHITCRDRNLIGLQSHLLGLSLLGIHEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNKGINTDGDALKTETHFNIAGGFDPHVRNIKAAVR
KMETKIESGMHYFITQPVFTKEKITEIYEATKHLDVPIFIGIMPITSYKNALCLHNEVPG
IKMSEEVLAQFEAVADDKEATYELSLSLCKSLIDHVHHYFNGLYLITPFERVDYSLELAA
YSKSITDHNQEVIL
>A0A1E7IP22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium C00003068|TrEMBL
MGTVLYEQGVPVDSCFENLNLTHPHLVTAVHQAYRAAGAQLLETNTFTANRARLAAIGLE
ADVHQINAAGARLARQAAGCDSDLFIAGAVGPLVGCDQDTLLSVADQQQMFREQMEGLAD
GGVDLFLLETFASLAELKLAISVAKKIGLPVVAQMTFFAEGRTREGLDGAQVSRELDEMA
RLGSGYGADVVGANCGSGPHDMLAVVRQMGATVERPISAFANSGFPQYVNGRHIYLATPE
YFAQRSQEMVASGASLVGGCCGTTPEHIAALAQRLKGVKPVTRIVAPQVVEGAKSAEPVV
TISSLRESSPLLKHDLKRKPITVELDPPRGLDCTQVIQRARQLAASGVDAINLAENPLAR
IRMGNLALAARIQDATGVPVIAHVTCRDRNLIGLHSEMMGAHLLGLRHILAVTGDPASVG
DGGGATSVFDLNSVGLLELLTALNSGRNLLGADLASCSDFCIGAAFNPNAAKLDGQLRKL
DKKIAAGAQFVQTQPVYSLEIVDRMNLALRDVSIPAFLGILPLVSERNAEFLHNEVPGIV
LPDEVRERMRGTKGAQGVAAGMEIAVEMVSARHSQSDGYYIMPPFGKVELAQELIEVIRS
FSP
>A0A661B0R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MLLDILKERVVVADGAMGTYLYSLDVPKGHCYDELSVSHPEIVQRVHREYLSAGAEIITT
NTFGANRYILEKYYDLGVKTVDINASAVRIAKKAIKNSSKNSFIAGDIGPITRPFESAEV
LSKEELEEIFSEQIETLVEGGVDILLFETYSNLNELLVGVNVARKLAPQIPIWASFTFVD
GKTLSGCAPEEIATSLNESGVHIVGANCGRGPREILDAAKHLAKVFTGYISAMPNAGQPT
FVDGEFVYPATPEYFASFARRCVSSGLSIVGGCCGTTPEHIKAISDSISGMRPRARKFVP
KVEFENSAAVRKIPRPKTSLEKKLASGFVLTMELDPPRGSEIGELVKVARFFKELGGDGV
NIADLPMALLKMSALGLAAAIRIRTGLDIILHFTARDRNLIGMQSDLLSAYALGIDNILA
LRGDPPAVGDYPFATGVFD
>A0A3N9NWH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MSARTKELLERVHTDILVADGAMGTALYAAGYSHRTCFDELNLSAPHQIETLHRAYVKAG
AQIIETNTFGSNTLRLAEHGFERQSREISRAGAILARSAAGEQRYVAGCIGPLNQVLEPI
GRVTLDQAREAFSYQIAGLLEGGVDVFFIETMSSLVEIREAILAIRDQCDLPIVASMTFT
EDGKTIIGDKPSEVLRALTEYGADVVGANCSVGPQAMMEVIERMARTSDIPLCAQPNAGL
PRVVGGRYIYLASPQYFAESALKFIGNGVSIVGGCCGTTPEHIQAIAEAVRGKKRGSPAQ
ISISEKEPEEQISGPRWGVPFNSFRENLGKKFQISVEIDPPRSHDPGPFIRHAQELKAAG
VDLINVADSPLARARMSALAMAHLIRRDAGIDVLLHMSCRDRNAIALQSELLGAHTLGVL
NILAVTGDPVAIGDYPMAHDIFELDSIRLAHMISQMNQGKDLTGRDLDEPTQFSIGVAAN
PTAPELEIEIDRFRRKIDAGAMFAFTQPLFEKETLDRFLDRVSGFSSIPLFVGIMPLRSS
KHAEFIHNEIPDMFVPESIRMRMQKSGTEGVKAGVEIAQEFLLNIKSSCQGIYLMPPFNK
FKMAVDVISVLPRDNSS
>A0A3A0G993|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
GRPVWVAGSVGPLGVAVAPAGGAEEAAAAAAFAEQVRALADGGVDVIVVETMRSTDEARL
AVAAARTACGLPVIALATFGEDGVTGDGHAPDAVARLLQSAGADVVGANCSTGPAQMLDV
VLRMAPAARVPIAAIPNAGLPTMVGGRYSYTSSPAYMAEMIAQMVAAGARIVGGCCGTTP
EHIAAMAATLATGAGQPRDARAAPRLSFPAREVETEGSPEPPGPTAFQRALGRRFTVAVT
VDPPRGFEAAAVPAGVRALVDAGRVDVVDVADSPQARAHVSALAMSVVVQDRLGIEAVLN
LGCRYRNAVALHAELMGAHALGVRNVVGIMGELPAHGDYPDATVVNDISDVRLVALMAAC
NRGSGGRDGQAAVPAAFHIGCQLDLGAVDLMRELHQFQAKVDAGAQFAFTDPVFDLRLVD
AALAHLGGRFPIPVLAGVLPLWNARHAAYLHNEVPGMEIPAAVLRRMAAAGDDGRAIGVA
IAVETIAALGDAVAGVRLMAPFGKHGVVAAVLDALAVSGPAAADRHLHPEAPPHVNAVGP
APASAEARGSP
>A0A7V4AWT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MTTNSNLQRVLESGGFAVTAECGPPRSADPDIVIKKGLLLKKHVDAVNVTDNQTAIVRMG
SLAASALLKSIGLDPVWQLVCRDRNRIAIQSDILGAAALGINNMLCLSGDHQSFGNQPHA
KNVFDLDSMQLLGAARDLRDSGRLIYDSNEIPPAARPGLFIGAAANPFADPFEFRAIRLA
KKIANGAQFIQTQCIFNLPKFTKWMKAVRDRGLADKVYILGGVTPIKSAGMALYMKDKVA
GMDVPDEVIKRIKGAPKDKQREEGVKLCVETIQKLRKIKGVAGVHIMAIEWEEAVPEIVE
AAGLR
>A0A7Z0M8L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MTGDTAISLEFFPPREEAARLKLAEAARQLAAREPAYVSVTYGAGGSTRGGTADTVRLMQ
SLGCDTAPHLSCIGSSRAELTEILDGYREQGIRRIVALRGDLPSGMGRYPGEVHYADELV
SLIREHSGDWFHIEVAAYPEVHPQAASASADLDHFVGKVKAGADAAITQYFFNADAYFDF
VDRVRARGVGIPIVPGIMPITNHTQLARFSSMCGAEIPRWLEARLADFGGDKASLRAFGA
DFVAALSQRLLDQGAPGLHFYTLNNAEATLAVWERLNVPKKEGAAKV
>A0A7C1VTJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MESTMSRFREALTKKEEFVITCEFVPGRGLKGKRIDNIMQFAEDVAGAEEIHALSLTDNA
GGNPAFSADILGYHLMAMGVDVIVHFSTKDMNRNAIEARAYALKRHALSNLLVMSGDYPI
AGFLGIPKPVFDVDSVMALHYLKRISEGLEVQEGRKTLTLEGTDFFLGAAASPFKWTEAS
SVLQYYKLEKKIRAGADFMVSQLGYDSRKYIEFIRYVRDYLGSDIPLIGSVYVLSAGAAR
FMNSGEVPGCYVDDRQLAAIREETKAEDKGKGARLERASRQMAIIKGLGYNGAHLEGLNL
KYQDVTTILGRAAEIGDNWRDYLEDFSYTPENPYYLFEGGEKVTVPRSGDAVSLTKTRKK
GIGNPSFWMTRLMHKLIFIENTLGYKLVRAISRLGEKSKGFYKLFRFLERNAKKAMFDCR
QCDDCALFELYYLCPESKCPKGMRIGPCGGSRPNGRCEVFEERLCIWERVYWRAKNRKEL
EKLKVIISPRDWGLYETSSWINYYLKHDHTAVTLDIPEKVKNN
>B7IHI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosipho africanus (strain TCF52B)|TrEMBL
MKISQIKDFFISIEVIPPLRGHSADNLYKAIDKIMPYNPAFISVTKHPPELEYYEIDGQI
LKLPKVKRPGTMGIVAALKMRYNVDVVPHLTCIGNSKFELEELLIDLDFLGIDNVFVIRG
DKKKNVIKKEWQYDYAYQLVQQISDMNKGKYLYQTAKKTNFCIGVAGYPEKHYESPNLKT
DIKYLKRKIEAGAQFVITQMFFDVEKYFNFVKLLRDEEINVKVIPGLKPILSYKSALKIP
GTFYVDIPEELIEKLDNARTPKEEFWTGVKYTIKLIEKLKENNVPGIHFFTMSNTDAIVE
ILKHI
>A0A0F2SMZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium BRH_c23|TrEMBL
MAEEKSKLQSLFEQGEFAVTCEIGPPKNAQGDGIRKHTEHLKPFVDAVNLTDNQTAIVRL
SSIGAGVHVLAAGGEPIIQMTTRDRNRIALQSDLLGAYSLGVRNVLCLSGDHQTFGNHQG
AKNVYDLDSIQLIQTVKDMREAKVFQSGEVIKQGEPRFFIGAVANPFADPFEFRVLRLEK
KIRAGAQFIQTQCIFDMERFEAFMDLARKRGLHQQAYIMAGVMPIKSAKVAKYMQKNVSG
MLVPDGIVERMSKAVDQPAEGVKLCIEQIKHLRTIPGVRGVHIMAVAWEEIVPEIVKGAG
LLPRP
>A0A5C8C1A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium sp|TrEMBL
MSSEVPHALPDPLVDALLAPKPTFSFEFFPPKDDEGEALLWSTIADLESLEPTFVSVTYG
AGGTSQERTVRVTERIAQESSMVPVGHLTLVGQSRDDLELVLKQYASAGVKHVLALRGDP
TGGPRAPWQTHPGGLEHAIELVDLAHQTGDFSVGVAAFPEGHPDARDRDHDAQVLVAKAN
AGAQFAITQLFFRASDYVELVERVSAQGSDIPIVPGIMPILNYGQVARMAELSGAAIPAE
VLEYIEPVIDDPAEVRRRGVELATQLCRDVIAAGAPGLHFITLNRSKASREILETLKGEG
LL
>A0A4Q4IYL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium indicum|TrEMBL
MKLALERLPSGRNRSLIKKSRKTRNPERQSDSIGSKLALPGQDAPILDLVRSFSLEMTAK
DVASLADAAPMIPAGTPISVTYLPGETMPARVAAARTVKSLGFVPVPHISARRIPSKDDL
VDFLTVLDGEIGIDRAFVIAGDPPAPMGPYEDALAVIRSGLLDRAGIGTVGISGYPEGHP
DIGREKLDQAMKDKIAALAEQGKRVEIMTQFAFDADAILDWLARIRRDGVAAPVRIGLPG
PASVGKLIRFAARCGVGASARVMVKYGASITRLLSTAGPEHLIESLARQRDPAIHGEAML
HFYPFGALVDTARFIRSHYGDACE
>A0A2W2F355|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea aridisoli|TrEMBL
MPVRNAEREVLEHVPATVPLTVTVTEARGIDTTLELTERLTRHGYAVAPHLPARQFIDKE
HVADVVARLREARVRSVFVIGGDAPRPAGAFADAYALLRAMEEAHHPFEEIGVAGYPEGH
PAISREALDLSLKQKAPMATHVITQICFDAGTTANWAAGLARAGVDLPIHVGMPGPVNRQ
KLMRISANIGLGPSARFLRKQRSLLWRFLLPGGHDPTKLARRLGAAASKTGGNLRGLHIF
TFGELRQTELWRRRLLSSIDPERAGPSFQ
>A8NEV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)|TrEMBL
MEQGLIDDVLKDVKDRGIETILALRGDPPRGEEEWIPSDPRFTHAIDLVKYIRGSQEYSS
HFCIGVAAYPDGHTESTCSEDEELEHLKAKVDAGADFIVTQLFYDVDRFLQWLKKVRAKG
ITVPIIPGIMPIQTYATFARLTKLCGTKVPSTLEADLLPIKNDDQLVKDYGVKYAVKTIH
RLRNEGGIQGFHFCTLNLEKSVQRVLEELKWRTGVVPAVQNKLIADSPDALSQNTLDSNL
LITPTSATNVATSVLTTSVLGTVSRTLPEAGRGELNDAATWDDFPNGRFGDFKSPAFGNQ
DPWGGPGGLGISRAEALQQWGYPKTFDDLTRIFLAHLHSEIPITPFSPTELCPESITILP
HLERLTKRGWWTVGSQPAVDGISSSDETFGWGPRAGYVFQKGFVEFFCDFHDVEAIEQRI
KQRGAGWVHYFMANNNGECRSNVPEDGRNAVTWGVFPGQEIQQTTIIEKESFLTWKDEAY
DIWNSWASLYHPDSAERQLLQKVANERWLVSIVHHEYKNPNALWTFLFDDDSGDV
>A0A3S0I505|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus radiophilus|TrEMBL
MTHIPHISVELVPRTRQSIEAELQQLKALWPGITTVNVPDLDHLELGSCESCALPGAQGL
TRIPHLRSSRVDVSDLGRLLRRLDELELTEVLVVRGDPPKDGRPVHDTSSVELIRALKAA
RPDLKVHAALDPYRQSLQDEQLYALKKIEAGAASLFTQPLFDTRLMEVFGEMLPGVPIYW
GITNVSTERSKAYWVTRNRAVFPKSFEPTLEWCTAFAREAVQHAQETHSHLYFMPIRTEL
RDFLGAVIPPAGGGTDPEGQGESGAVNGVLADQSGRQASAFG
>A0A4Q7NZ16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimarina brevivitae|TrEMBL
MKVTDHIEQAKGKTLFSFELIPPQKGRSIKELYDNIDPLMEFKPPFIDVTTSREEYIYID
RDGLLDKKLTRMRPGTVGICASIKHKYEVDTIPHVLCGGFTKEETEYLLVDCHYLGIQNV
MALRGDAMKEEKYFTPTKGGHAYANELVQQITNMNKGQFLHEVIETDNKSDFCIGVAGYP
EKHMEAPSMDSDIRRLKEKVAAGADYVVTQMFFDNKKYFDFVTRAKKAGITVPIIPGIKP
IAIKRHLQLLPQVFKLDIPDELVKAVESCKNNKEVRQVGIEFAIQQSKELMEFGAPVLHY
YSMGKSDNIKKIAAAIF
>A0A1S1HCM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas haloaromaticamans|TrEMBL
MSVSIAQMEEARRALDAPLFADLAGDCQVSFEFFPPKTEKMEETLWNAIETLAPLGPRFV
SVTYGAGGSTRERTHATVARIARETAIPAAAHLTCVDASRDEILDVAREYWAAGVRHIVA
LRGDPPREGEKFQAHPDGFENAAALVAGLKSVAPFEISVAAYPECHPDSADVAADLDNLK
RKIDAGANRAISQFFFSADAFFRFRDAVEAAGINAEIVPGILPVSNVAQTRKFAGMCGAA
IPAWMDRLFEGLDDRPAARQLVAATIAAEMCRKLYAGGVRHFHFYTLNRAELSYAICHLL
GLRPNPAAAEKAA
>A0A1C1CW37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cladophialophora carrionii|TrEMBL
MASGHDDRLPTLFSSLDPSSHYFSLEFFPPKTSSGFSNLQSRLARMATALRPLFVTVTWG
AGGSTATKSLELAELCQRQLGLTTVLHLTCTNMKKDMVDEALEAAKEIGIRNILALRGDP
PREEYKDATSVGETEGGSGGAGTGSNEEFTWAIDLVRYIRRKHGDYFAVGVAGYPEGHAD
ESHPEQGKQSVEHDLPYLVGKVSAGADFIMTQLTYDMDAYRKYEDRLRNYADPAGRRVFA
KIPIIPGLMPIQSYQIIKRITKLSHAKLPEDISKRIEAVKSDDEAVKKVGVDVLSELVEQ
MKTLPQPDGVPRGFHFYTLNLEKSVAFILERTGLIPPVSSEGSTEDRDGDSSSDPDAVVD
DDKRDGTATITKEQADQDAHQARDSAFSRRRRSSINAQPHNRVIMDRPSRSPAQARPDGD
TDPPNGRSSSLTAQHSARDRGTGVPASSPTRRHNLLISEGQGSLGREATWDDYPNGRFGP
SHSPAFGEIDGYGPSLKVSPLMARKLWGHPKSAKDVTEIFRRHVSGELAGVPWSDDIDPS
GGDGTTMSKDTAGALRAETDVIRSELLSLISKQNYWTLASQPAVDGAPSSHPIFGWGPPG
EGFVFQKAFVEFFCSRDEWETRLKDRLRKYGSEVLSWMKTDVHGAFESAQHAPRPANGVK
RAATDETTNPISTMNINASAGVSDVDTVNAVTWGVFPSREILTPTIIEAESFRAWAQEAY
AIWSEWKRCFPRGSEEAAFLDRARGDVVLVNIVGQEFRGGHDGQGGRLWKILLDEDQKDG
RQIGMR
>A0A2H6F289|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Abin06|TrEMBL
MNFKEALNSGKFAVTAEVGPPKGTDIKEMLHDAEALKGKLDAVNVTDNQSAVMRINSLSI
CKILLDMGHEPILQMTCRDRNRIGLQSDLLGASVLGIRNVLCMTGDHPNAGDHKEAKSVY
DIESVQLLRVVDSLNNGKDMMGNDMKGATDFFQGAVVTPEADPVEPQLMKFEKKVAAGAN
FFQTQAIYDIGKFKEFMTYAKKFPVKILAGLVLLKSAGMANYMNKFVPGIKVPGDLIDEL
KAAGKGNALDTGINIAARHIRQLKEEEICDGVHIMAIGAEDKVPLIMERAGLL
>A0A838ES24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionales bacterium|TrEMBL
ITNLPRNFFIDMPDDLIDAIDNCRNDDDVKNVGVEWAIHQAKELMEKGVPCLHFYSMGKS
TAIQQIASKLY
>A0A7W9WJM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces paradoxus|TrEMBL
MALGTASIRSDHARTVRDMLADGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSLDWDTDVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLERIGSLTNAAF
PAALKERILTAKDDPAAVRSIGIEFATEFCAQLLAEGVPGLHFITLNNSTATLEIYENLG
LHQSPQA
>A0A3D5LTJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MEKLKIYLEAHKLITDGAFGTYYSRVYDTNELPESVNITMGRRVTDIHKEYINAGAKLIR
TNTFAANTVNLECNFDEVKANIKAAVANARQAVKECGREVYIAADIGPIPNDNLFDKQTV
VDEYVDIAKVFLEEGINVFVFETFADLSNISDAIDYIGSAATGGINIADSVVTDRPFVIT
QFAINQFGYSNCGLSSSKLVKLADDNPYIDALGFNCGIGPGHMEQFILKERRHTDKYLSA
LPNAGYPQAVSGRMIFSDKNMDYYSDKMCELLNAGADIIGGCCGTTPDYIDRIASKADFT
QNRQGEGCDWETDNSVQAVNTAFYHNKEGKKLIAVELAPPFDSNADKLLDAAHYLKSKGV
DVLTFPDSPSGRTRADSILMAEKVSRQTGMCVMPHLCCRDKNAIAIRSQILGADINGINN
FLVITGDPIPSVMRSSVKSVFNFDSVGFMNILDDMNSEQFADQPVTYGGAINQGRKRLDI
EIGRVKKKMEAGATFFMTQPAFCDEDIERIATIKKETGARILCGIMPLVSFKNASFMKNE
MTGINVTDEVLLRYRPDMTKEEGEQAGIDLAVEIINKSIDIVDGYYFSFPFIRVHMLDKI
IKQSELYVNN
>A0A7C0XDV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MFRELIKEKDVPITYELWSPRGCMVNQHFEAVSRFKDKLDAVNIPDNPLATLRVSSIAYS
KIVMDRLKIDIIPHINCRDRNSLALQSDILGAHLLGIRNLFIVGGDKPAGKTVKTKGVWA
VTSTELCKIVKHLNEGFARSNDDLVEIYGKTDFFVGGAIVFDRKNEVEIISRKIEAGFDF
FQSQIVFSHEKVLNFFREAEERGVTINKPVLVGLSPQPSEKALNKLVRFLRVEMPKSSAD
RLRRSGDFAGEMLSVCLEVADELKSALSPKYKIGFHIMPLGYDDLGRKLVEELRE
>A0A838F3Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionales bacterium|TrEMBL
MAKVTEHIKNAKSTLFSLEILPPSTGESIQKLFDNLAPLMEFKPKFIDVTYHREEFVYKK
MANGLLEQKSIRKRPGTVSICAALMHKFNVDTVPHIICGGFTKEETEYALIDLNFLGIDN
VLALRGDCIKGQKSFEPSVGGHKYADELVHQINQMNKGLYLSDELQNPTPTKFCIGVAGY
P
>A0A7J2IXC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MDLAGNKIEHPPKFHVGIAANPNAEPIEPELLKIERKVEIGVDFIQTQCVYDIEVAKAFL
KEAERWRVPVIIGITPFKSVGMMKYMIKYVPGIKVPEEIQERIIKAKERGGKQAVYEENV
EIFTEMIGELKRTTRLAGCHMMAVGFEWIVPKIIERVEGGQPSYLSLEG
>A0A497NN62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MFRELVKEKAVPITYELWSPRGCMVNQHFEAVSRFKDKLDAVNIPDNPLATLRVSSIAYS
KIVMDRLKIDVIPHINCRDRNSLALQSDILGAHLLGIRNLFIVGGDKPAGKTVKPKGVWA
VTSTELCKIVKHLNEGFARSNDDLVEIYGKTDFFVGGAIVFDRKNEVEIISRKIEAGFDF
FQSQIVFSHEKVLNFFREAEERRVTINKPVLVGLSPQPSEKALNKLVRFLRVEMPKSSAD
RLRRSGDFAGEMLSVCLEVADELKSTLPPKYKIGFHIMPLGYDDLGRKLVEGLRG
>A0A7C3WYI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MSKPAYSNLMNALNEGKFVVTGELEPLKTTDLSSIINAAKTIKEHVIAVNVTDNPTAFAY
TSPLVTCYLIQKETGLECVYQMTVRDRNRLAITSDLLAASILGIKNVLALSGDFVNVGDN
PQTKPVYDIDSTQLIYLVRRMVDEGTDLAGNKIINPPKFNVGGAANPNAVPLEVEVYKLL
RKQNVGVDFLQTQSVYDIERLKRFFELCDSIGIRVPILVGVTPIKGIKMLEWLSKFVPGI
HIPDEIQERLRKARAKSKEAFNEENVEIF
>A0A537GD04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MCRRVPSWHGRSGLRLTRLHELVGRKRVVTVELIPDRVSPADLGILRGRVDAVTVPALRN
GTADPVFPSGHHISPQQRSIAAATLLRGTGLDAVPTITCRDSTVADVFSRLSDLLSVGID
NLLVVYGDPSGSTFDRYEMRASHHLIDWVDRTSNGRFSVWAITNQYHHDQEREIARTLIR
QEAGARIVLTNAVFEADGVLEYRDALRDAGLSVPISVQISVIHSFENLSFVSQKLGIPVP
IGVQRRLRRDPGAGVEVAADAYRALKSEFDGVHFSYLYRKQSPIPVYTRLLDLIGIPFQA
PGLNGELMAPDQLVR
>A0A842R4D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
NRNALFGDVMAAAMLGIRNILVLTGDHSALGDNAGAKPVYDLDSAQFCYMLSKLIDDGVD
LGGNEIKGELKMNFGCVVNPNSDPLEPEILKLERKINCGADFVQTQTVFDIDQTKDFLKQ
TRYLNTPILVGLFPMKNYGIASYFDKYIPGVSVPKDLLSNLKQTKKKYIPDRKERHQAVD
KVNIEFFTPFIKEIKKTTSAAGIHCMAVEYERLFEPLLALVEQG
>A0A537E8C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MRLSDRARHHNLVTIELIPDRVVPSDLALLKGRVDAITVPALRNGHDDPSYPRSFPVTPQ
RRSLASATIINRAGITAVPSLTCRDCRRSDLSMIANQVEDGLGNVLIVYGDPYPEPRPGT
YEFTKTNELIREISSLSGGRHPCIGAVTNQHANDRENEISRTISRVDAGADFIVTNVAFD
ADRVLEHRDSLLEAGLNVPLFIQVSIPLSLDNVLFVSQKFDIPVPVHVKNKLLNDPIGGS
LAVATEAYEALRGEANGIHFSYLFRQRNPIPTYRHLLETIGVGGPELAPLAASTVKTLSS
S
>A0A0U1L0M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa ovata|TrEMBL
MSEVAIDKQAVLKTDSKLEKLYSLGHFVVTGELGPPQHSDGHELEHHAVELKDIVDGFNL
TDNQTAIVRLSSIAAGVHVLKGGGVPIIQMTCRDRNRIAMQSDLLGAYSLGIRDVLCLSG
DHQSFGNHPTCKNVYDVDSVQLISMVKKMRDEKKLLSDAAIKTNEPRFFIGAVENPFGDP
FEFRAIRLEKKVNAGADFIQTQAIFDVEKFARFMEMVVARGIHERTKITAGILPVRSVKA
LQYMKKDVAGMEIPDSLIERMKKAEDPKKEGIQVSIELCNQLKKIPGVAGIHIMPVGWEA
ALPEIVKGAGFLPRPKV
>A0A416DEL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. AF35-5AC|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTNSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>A0A1Y5GH09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium 59_46_T64|TrEMBL
MTQTAKTKTPNISFEFFPPQNLEASFRLWDTVRALAPLDPTFVSVTYGAGGTTRELTHDA
VATIHKNYGLNMAAHLTCVSATRDETLAIANSYADAGVTEIVALRGDPPKGSTGFEPHPG
GFNNSIELIEALAETGKFRLRVGAYPEKHPEARDTAADVEFLKRKIDAGAHSAITQFFFE
ADTFFRFRDACVKAGIDAPIIPGILPIENWKGTRNFARRCGTSVPQWLDDAFENAAAQGQ
EGLLSTAQCTELCSDLLEGGVEDLHFYTLNKPALTRDVCHALGVMPKASLENVA
>A0A3D5LU57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKIRDIIDREQETLSMEVFPPKKDTDFEMVKEAALHIASLKPSFMSVTYGAGGSTKGNTI
KLASEIQKQYQVPAMAHLTCVCATKESINTALTEMKQAGIENILALRGDIPKDYDGEVFT
EFQHASQLVELIKKTGDFCVGGACYPEVHPDSKNKFDDINGLKEKVKAGCEFLTTQMFFD
NNIFFNFMYRVREAGIHIPIIPGIMPITKRAQVKNAVKLSGCNVPERFKNIIDKYGDTEN
AMKQAGVIYASDQIIDLLANGVKNIHIYSMNKPEIAKGIQDNLKGIIL
>A0A3B8UMP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
GGCCGTTPDYIKNISEMIRSSHISCNINIDTDGDFNKTPVKNSAFYCGKEGKKLIAVELA
PPFDSDADKLMDAAHYLKEKGVDVLTFPDSPSGRTRADSILIAAKVSRQTGMCVMPHLCC
RDKNAIAIRSQLLGAHINGINNFLVITGDPIPQMIRSSVKSVFNFDSVGLMNIIEDMNED
QFKYEPVVYGGAINQGRKRLDIEISRVKKKMEAGAAFFMTQPVFSDEDIKRLSTIKKE
>A0A3D0R0X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp|TrEMBL
MAFGTSSTRTDHARTVRELLASGARSYSFEFAAPKTAKGERTLWNAIRRIEAVAPTFVSV
TYGAGGSSRDGTVRATERIATDTTLTPVAHLTAVGHSVADLRNVIGHYADAGIRNMLALR
GDPPGDPMGEWVRHPQGVDYAADLVRLIKESGDFCVGVAAFPEMHPRSPDWQSDVRHFVD
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFAQLSNAAF
PPGLADRILAVKDNPSAVRSIGIEYATELCARLMAEDIPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A1X7AJK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parendozoicomonas haliclonae|TrEMBL
MTAISYEFFPTQTEAGAEKLQIQAALLAESNPEFFSVTYGAGGSTRDRTRGTLLATQQTT
GLPVMPHLACIGDSKDNIRSLLQDYKSLGINRIIALRGDRPSGMGNMSNSDFQYASELVS
FIREETGDHFHIEVAAYPEVHPQAWSMDADLENLRRKVEAGADSAITQYFFNPDSFFYFM
DRLAAMGIEVPVVPGIMPITNYMKLARFSDACGAELPRWVRKQLESYGDDSASIRQFGEE
VVSQMCEKLIAQGVPALHFYTLNQAAPSLGIVKNLGLFPNQN
>A0A1B8HJR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morganella psychrotolerans|TrEMBL
MSFLHVDQHEALNQNLAELAGRVEVSFEFFPPGTPEMENTLWQSIERLSVLKPKFVSVTY
GANSGERDRTHSVIKGIKEKTGLIAVPHLTCIDATRDELKTIAKDYWDNGIRHIVALRGD
LPDNSRKPDMYAADLVGLLKSVADFDISVAAYPEVHPEARSAQADLINLKKKIDAGADRA
ITQFFFDVSTYLRFRDRCAAAGIDVEIVPGILPVSNFKQLQRFAGMTNVRIPGWLGNMFE
GLDDDPESRKLVGASVAMEMVKILSREGVKDFHFYTLNRAELTYAICHTLGVRPAVACVA
>A0A243A488|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar navarrensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A890VW41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos mutus grunniens|TrEMBL
MGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITGHL
NKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKGHP
EGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCPVLPGIFPIQGY
HSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYT
LNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQEWD
EFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLSGE
PNQNGYKVTCLPWNDEPLAAETSLMKRRS
>A0A101GBT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinimicrobia bacterium 46_47|TrEMBL
MDKGHETSQKPRNFLACLRDHVLLFDGAMGTMIYERGVYVNQCYDALNIQKPDLILGIHR
DYADAGADALTTNTFGANRFLLKKYGYEERTVEINRKGAELARQIAGEELFVAGSMGPPP
DRMEPLGKLTVRELREAYHEQAEALIHGGADILILETFSDLGMICEIIREIKSAFPKVPL
IGQMTVDKEGRTSLGSTPEIFASEIVRAGADVVGVNCSLGPSTMLEVAERIFRISPIPVS
AMPNAGLPQRVDGRNIYFSSPEYFSEYTRRFVQVGVRIVGGCCGTTPDFIRSMRNALRSI
QPRKRIEITSLPPQHDEDVDLIPTSKKSRLAEKISRGEFVTTVEIVPPQGPDPRKAVEQS
RILFESGVDAINIPDGPRALSRMASSYLSLIIQQETGGEVIQHFTCRDRNLLGMVGDFLG
AYAAGIRNILIITGDPPKMGTFPDASAVFDVDSIGLTRVASILNHGRDLGGNVLKKATGF
FIGVGANPGAINPEEEIRRLEEKRDSGAEYIMTQPVFDPEIFLTFMDRIRHINLPVIAGI
WPLVSVRNAEFMNNEVPGANVPDWVMERLKRSRTRDEARETGLAIARETLRILKPYLQGA
QISMPFGNVKYPLEVLKEVLS
>A0A7X4G118|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas alkaliantarctica|TrEMBL
MSRQEHPLGISFEFFPPNTEAGRAKLMHARDQLAARRPRFFSVTYGAGGSTQARTREVVR
EIGQSGITTAPHLSCIGSEKAQLRDLLAQYREEGIDSLVALRGDMPSGMASIGELRYANE
LVEFIRDETGDHFEIAVAAYPESHPQAPNLDKDVENFARKMQAGADMAITQYFFTADAYF
HFADKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTEVVSRLCQRLLEGGAPGLHFYTLNQAAPVLKIVDNLG
>A0A0S7LLL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poeciliopsis prolifica|TrEMBL
MVNQVQQVDGSWQSCRGDSSGNSSGESSKESSRCSTPLLDADRSDRLREKMRKRMDSGDQ
WFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVN
YCGLESVLHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGGTAGDMKGSGKV
>A0A6P1KJ82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. ATCC 53789|TrEMBL
MYHTHSHTAFRRAVQAGEFLVTAEVAPPKGGNPAHMIQMAATLKGRVHAVNVTDGSRAVL
RMSSLLASVILSQNGIEPICQVACRDRNRIALQADLMGAHALGIRNILALTGDPVKAGDH
PDAKAVFDLEAVRLLQLIRKMNQGVDYNEKPLTDGALDLFVGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFERLEKFMDTIASGYKKPILAGIFLLKSAKNAQFINRCVPGVN
IPQHIIDRLAKAKEPFEEGIKIAAEQVQIARQLCQGVHLMAVKREDAIAPILDLAGISPV
NQLVSK
>A0A0B0KEJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. neg1|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GQGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A495VY53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix australiensis|TrEMBL
MTTVVERLTGGNPVFSVEFFPPRDAADELVLWRAIRELEALDPAFVSITYGAGGSSRDRT
IRTTGRVVQETTLVPMAHLTAVEHSVAELRNVIGWYAAVGVRNILAVRGDPPGDPNGDWV
RHPEGLTYAEELVRLCRELGDFCVGVAAFPYGHPRSADLDTDTRYLVAKLRAGADFAIAQ
LFFRPDDFLRMRDRVAAAGCDTVLLPGLMPLTTPRTLAKTVELSGAPVPPEVARRLEPHL
DDAASFRKAGIDLVTETGERLLAEGVPGLHFYTFNRSKATREVVGRLGLVPARA
>A0A179CYT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bibersteinia trehalosi Y31|TrEMBL
MSYARTTDLLNQNLAELNGKVNVSFEFFPPKTEKMESLFWDSIQRLATLKPKFISVTYGA
NSGERDRTASLVKKIQQDTGIISAPHLTGIDATPDELRQIAKDYWENGIRSIVALRGDLP
AGYNKAPFYASDLVKLLKEVADFDISVAAYPEVHPEAKSAQSDLIYLKQKVDAGANRAIT
QFFFDIESYLRFRDRCVTTGIDVEIVPGILPILNYKQLEKMAKITNVKIPAWLHHAYQGI
REEDKSTAQIVGANIAMEMVKVLAKEGVKDFHFYTLNRADLSYALCHSLGVRAA
>A0A494RBS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. TMW 2.1634|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETADHFHIEVAAYPEMHPQARNFEDDINNFVRKAHAGADSAITQYFFNADSYFR
FVERVEAAGVMIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A1C5VR92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Bacteroides sp|TrEMBL
MKVIDLIKNSKEPIFSFEILPPLKGNNIQKVYHVIDKLREFDPKYINITAHHSEIVYLPQ
PDGNLKKTTVRKRPGTVAIAAAIQNKYGIQAVPHIICKGFTKEETEYALLDLNFLGITNL
LLLRGDSKPLDIAAKDLYLYNEHATDLQEQVNRFNQGISLDGSKIEGIETPFSYGMACYP
EKHEEAPNMESDLFYLKEKVRNGADYVVTQMFFDNEKYYAFVDRCRQEGIEVPIIPGIKP
VVFKNQLNVLPKVFRTDIPEAFASELRKCENDEEVKAVGVEWCKAQCKDLLAHGVPGLHF
YTFMASDSVYKVAKEIY
>A0A2K8RE04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. M56|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRAELRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWISHPDGLDYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIGHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATELCARLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>A0A2V1D5U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Periconia macrospinosa|TrEMBL
MERITDKIKALPEDANFFSLEFFPPKTQMGFANLQSRLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMSRSLIDDALEEAKVLGIRNILALRGDAPRSEE
YREEGQPPEEDSNKDFTWAIDLVRYIRKQYGDYFCIGVAAYPEGHSDESHPEVQDPKIDL
PYLVEKTAAGADFIMTQLFFDVEAYDEFEKMLRSHESGVFKTIPIIPGLLPIQSYNILRR
VTKLSHAKIPPDILSRLDQVKTDDEKVKQVGIKVLGDIVEHIKKRPNPGPRGFHFYTLNL
EKAVSHILEDCKLIPDPNVDSDSESAIETTPAINLTAPDGALRVKSRSRLSSINSGPHNR
FITSARPSQNSNPSQADYSAHESEAGVPRGPINTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAFGEIDGYGPTLHVSTGQALKLWGTPLSKSDISLLFRKHIEGTLPALPWSEQ
GLSPETSTIATHLLALNDKGWWTVASQPAVNGVPSTDPVFGWGPPNGFVFQKPFVEFFIP
SSDWATLLPRLQSHEQITYFASNAKGEFRASNEHAVNPVTWGTFKGKEIVTPTIIEAVSF
RSWCEEAWSIWREWRRIYPIRSKSSQVVRECGEDVWLVNVIWGDFLEGDGLWEVLLGEE
>A0A2N3NZL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. BI3|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7Y8HD52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MGFQESLAAGKFVVTSEIGPPKGTHIQEMMADAEMLRGRVDAINVTDLQSSVMRLGSLAV
CHLLQEKGLEPILQVTCRDRNRLALQADLLSASILGIRNVLALTGDYASLGDHPQAKPVF
DLDSVSLLGVIKKLENGTDMVGNSLLGAPRFFPGAVVNPGGNPVEAQVLKMEKKIKAGAN
FFQTQAVYDVGAFEKFMKRVTPFKVPVLAGIILLKSAGMARFMNKNVAGVFVPEPFIQRM
AKAEDRVKTSIEIGAELIRDLKGMCQGVHIMPIGWESKVPALLDAAKL
>A0A7C6NIR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobiaceae bacterium|TrEMBL
MRTSELFKKKRVFSFEIFPPKRTAPVQTIYDTVEELVDLKPDFISVTYGAGGSETSRHTL
EIASFIKNEHSIESVAHLPCIYLSKDEVLEMMEEFRKNNIENILALRGDINPDLPPKKDF
KYASDLVSFIKENGDFNIIAACYPEGHRECGSIVEDIRNLKTKVDAGADQLITQLFFDNE
YFYSFRERAAIAGINVPIQAGIMPVVNKKQIERMVTLCGVDLPKKFLAMMQRYEHNPEAM
RDAGIAYAVDQIVDLVAQGVDGIHLYTMNNPYIAHRIYEATKTLLAT
>A0A537M3L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrabacteria group bacterium ANGP1|TrEMBL
MTSPRHPLLARLDGGPLLCDGAMGTLLYERGVPYDRCFDALNLTDRERVLNVHLDYLRAG
AEMIETNTFGANAVKLDAHDLGGRVRDVNWHGAKIAKEARDIIGRAIWVAGSVGPLGKPV
APFGRISAAEARDVFRAQIDALVEGGVDALVLETFTDLDELLEAVRAARAACDLPVIAQM
SFTDDGRTRYGHGPAEVVAGLEQAGVDVIGANCSVGPVPMLEVIQRMASLTRRPLSAQPN
AGFPALVDGRYLYLSSPTHLAAYARKMVEAGAVVIGGCCGTTPAHISAIGQAIADLRPAP
FRAVVPEAPGRAEPIAPPVDQPTQLAEKLGRTFVISVEVDPPKGLDATKDLDGARLLKEA
GADVIDVGDSPIGRIRMGALAMCYLIQQQVGIETIIHFTTRDRNLMGVQADLIGAHALGV
RNILALTGEPPRGDYPNVTAVFDVDSVGLVRIIRRFNEGQDLAGRSIGRPARFLIGCALD
MNPETLDREVPRLERKLEAGADFFMTQPIYEPETLDGFERRVGKLPVPVLLGILPLQSFR
HAEFLHNEVPGITIPKWVRDRMQAAGGAGREEGLRLGRELLGALLGRIDGAYFMPSFGRY
ELVATLVREVRTRVAGHAARTRG
>A0A151ADL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halalkalicoccus paucihalophilus|TrEMBL
MSLIPDSSGAVEGVPKLLSEPRYELMPFDSFGEQMDHLPDGATIAITTSPTLGLEATLEW
TEKGAAAGYEIVPHIAARYVRDREHLAEVVDLLADAGVTDLFVPGGDREEPVGEFESAHD
LLVALDELNHPFEEIGITGYPEGHAFLSEETLTGAMAQKEPYATYIVTQLCYDPEAVVEW
VGEIRDRGIELPVEVGIPGVLSYQRLIGISKKVGVGDSIEFLRKTTSVVGFVRQLIGSRG
VYTPDELIEGLAPYVNDPAYDIRGVHIYTFNQVPDTENWRERLLDERL
>A0A2H6JP02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Bbin14|TrEMBL
MTTQNKFSRSLLDPEQFTITYELVPGQGSGGRRHERLLEFARQTYEDGRIKALSITDNAG
GHPALAPIAIGSEVQAIGLEPLLHFSLKDKNRSQVESHLFLYHRQRFHNLLILGGDFPRP
NYYGQAKPVFDLDSVQTLHLLREMEDGSYQRGSATGRGTTFAPLSFLRGCVVSPFKTTEA
EQVWQYAKLLKKIAAGTNFIITQLGYDVCKLEELIRFLRETGNTLPVLGNVFIPSLGVAE
YMGRGGVPGIVFPQQLIRRMQEEAVRQDTESRLLRAAKMICVLRGLGYSGVHLGGNGLNF
AKVRFVLDTAEAMQDQWPSLREDVHFPADNSWYLYPPSANGVCGKKRGALAPGRRQKAQR
LHQLTHRLLFAPDQSLTSRLFGRFCRYCAKSKGRTALLGKLEKAIKALLFSCRMCGDCTL
AESTYLCPQAGCPKKLLNGPCGGSRNMACEVYPDRACFWVRVYDRLDPGSGPEQLGAEPS
LPPKDWALDQTSSWINHFTGRDHKRLDPPPGDRPLRPGNEQGKQDQ
>A0A6J5GX34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia fynbosensis|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLASLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHLSCIGSSKESLRAILNEYRKHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFANKVRAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTDLCQRLIDAKVPGLHFYTLNGAAATKAICERLGA
>A0A2H6JMJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Bbin14|TrEMBL
MKSGSNLERVLASGAFAVTGELGPPKNSDPDIVRQKARILKGNVDAVNITDCQTAIVRMS
SIGAGLIAQSEGVEPVIQMTCRDRNRIGMQSDLLAASAMGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQMLGMVRDMRDGKKFQCGEEIKGPEPRFLLGAAANPFAHPFEFRAVRLGKK
VANGADFIQTQIIYNVDKFARFMEMVRDLGLHEKCSILAGVTPPKSLGMARYMKKFVPGM
DVTDEVIERMKGAEDKQQEGINICVDIINQVKEIKGVAGVHVMAIGWEDAVAEIVESAGL
LPRPTFDEEKEVQEPVAAPETIVVRGDADNMLAEAKAEAEKIIAAARKEAELITSRAAAE
PAPVETAGPTEAVAVATDDAGEHEMNEKMRLMALESVEQGLNALKKAYGLNDDQFDALLK
FVETETILKREFATAKKTPAAPAAPAAPVTPAAPVTPAAPVAPAAEDSAEKAAAVEAEAK
AEAEAKAEAEAKAAREAEAAEQAKIAAAAKAKEEAAAKAREEAEAAAKAKAEAKAEVKEE
AAPKAEPAKTAPAAGLAVPDLAVEKTRFSERSTKVPESTYHQAYSGSIREVVLGNDDQSV
TVGGAKVLPFHLFEGDMPRKPLIAMEILDIKPDNWPPTLLQYFEDVVGNPVDWAQKCVNE
YQADALNVSLIGTDPNGLNRSSTDAARDAADVIKAVEVPIIVWGCGNIDKDTETLRELTS
LIGDKKVCLAPLQDGNYRPLGATAMAFQHPMVAASPIDVNLAKQLNILLENLGVSLDSVL
MDPSIGALGYGIEYSYSVMERIRIAALTQQDDKLQVPIICNLGREVWKTKEVGLPSDDLL
GDQERRGIMMEAMTASCMLLAGGDVLIMRHPKAINMTKSLINGLMA
>A0A2D5LGB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPGNENMEKTLWKSVERLAPLKPAYMSVTYGA
NSGERDRTHDVVKRIQQQTGVTAAPHLTCVDASAEELKQIARDYWDSGIRRIVALRGDLP
KGVEKTDMYASDLVALLKDVHDFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTGVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKLYEGL
DADDQTTRNLLGANIAMEQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVKPQNAG
>A0A416V4S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. AF17-28|TrEMBL
MKVIDLINNSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSIQKVNIRKRPGSVAIASAIQNKYNITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTIEAGQNTDLYHEHATDLQEQVNNFNKGIALDGSRFEANETPYSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDEEAKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVYKVAKEVY
>B5JFK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiae bacterium DG1235|TrEMBL
MSQTPISKLFSESRPLLSVEFFPPKSDEALDELVESAEELAPYSPDFVSVTYGAGGSTRD
RSAKACQLLRDEHDFNIMPHLTCVGASRGELAETINGLYEAGYRNIMALRGDPPKDSNSF
VVAKDGFAHASDLVSFIKELHPDISIGVAGYPEKHPEATDLATDLRHLKTKVDAGASFIT
TQLFFDNADLYRFLDQAADQGIEVPVIPGLMPVLSIKQIKRIASLCGASLPSELETHLNA
AGDNAELVRQIGVRWASEQLQDLVEQGLPGVHLYALNRSDIATELMSAFRSTEPTT
>U2ZIN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas alcaligenes (strain ATCC 14909 / DSM 50342 / JCM 20561 / NBRC 14159 / NCIMB 9945 / NCTC 10367 / 1577)|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMGVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVGVPTAPHLSCVGDSKDELRSLLSQYKNSGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGDHFHIEVAAYPEVHPQARSYEDDLQNFVRKCRAGANSAITQYFFSADCYFY
FVERVRKLGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDLESIQAFG
EQVVTEMCERLLQGGAPGLHFYTLNQADASLAIWNNLKLPR
>A0A4Y1YNQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas stercoris|TrEMBL
MQSQKIFTPTFSFEFFPPQTPPGIEKLRAARVQLAQFNPKFFSVTFGAGGSTRDRTLETV
LEIQAEGYPVAPHLSCIGSTRDNIRSILEKYHANGIRHIVALRGDLPSGMAQAGEFRYAN
ELVAFIREEFGDAFWVEVAAYPEYHPQSRSALEDFTNFRRKVEAGANAAITQFFYNVDAY
LHFVEMCETANLNIPVVPGIMPISKFSQLARFADGCGAEIPRWMRRKLESFGDDIPSIQA
FGLDVVTAICARLLEEGAPGLHFYTLNSAVLPTKIWQRLGL
>A0A0Q9M031|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Soil750|TrEMBL
MLKDKILRRETGIITYGMTPPKETHSLEKMAEISHKQCERLQKLQIDGLILYDVQEESDR
IDQDRPFPYLQTVDPTTYSKTYLSKLHIPKIIYRCVGKYTEEQLAEWIQADLEEERFSVF
VGASSSKQDVHMGLPEAYALSRKLNENLTLGAVVIPERHMKKDDEHLRMINKIASGSRFF
ISQATYNVEASKNFLSDYYYHCKENKLDMVPILMNIAPCGSTKTLEFMKWLGISIPKWLE
NDLKYSHDVLDKSVSVSQQIFEEIFEFGLEKGIPIGCSVESVSTRKVEIEASIQLVHEIK
AMMAKKMRSSFVF
>A0A653JBG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. 9U|TrEMBL
MMSDVIEVQRSAPASSPAAGVSPFARLPGDIAVSFEFFPPKTEKMDAQLWDAISELAPLS
PSFVSVTYGAGGSTRERTHATVARIVRETSLKPAAHLTCVAASKAEIAEIAEQYWQAGVR
HIVALRGDPPPADGGKFVAHPEGYASAAELVAGLKAQHDFEVSVAAYPEVHPEALSDQHD
LDNLKRKLDAGATRAITQFFYSTDAYFRFLDKVLAAGIEAPILPGIMPVTNFAAIRRMSG
NTEIPEWLETMFEGLDDRPGPRALVAAVAAADICRRLYEGGVRDFHFYTLNRAEQAYAVC
QLLGVRPKEA
>A0A1I3EVU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas xianhensis|TrEMBL
MSAQEHPLGISFEFFPPNTDAGREKLLHTRDALAERNPRFFSVTYGAGGSTQARTIHTVN
SVRECGINTAPHLSCIGSEKTQLRDLLNQYRDNGINSLVALRGDLPSGMGGIGELRYANE
LVEFIRAETGDHFEIAVAAYPEAHPQAPSFEHDLQNFVRKVQAGANLAITQYFFSADAYF
HFVERAQALGVEAPIVPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIQAF
GEEVVSNLCQRLLEGGAPGLHFYTLNQAAPTLKVLDNLK
>A0A316HRK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentzea atacamensis|TrEMBL
MTSVVERLQGQSSVSAPKFSVEFLPPRDAEDEKILWKAVRELEGLDPAFVSITYGAGGSR
RDRTIRATGRIAQETTLLPVAHLTAVDHSVAELRNVIGWYAAIGVRNILALRGDPPGDPM
GEWVAHPEGLNYADELVRLVRELGDFCVGVAAFPYGHPRSSDLDTDLKYLLRKLNAGADY
AVAQLFHEPEPFLRLRDRVAEAGCSAAILPGIMPMLSARGLAKIVELSGADLPVEISRRL
EPYADDPAGFRATGIDIATEMCQRLLEEGVPALHFYTMNRSKATKEVLGRLGLVTRV
>A0A520WJ84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGT
>A0A841NDI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium shigense|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTPGGHASAMDLVHQINDLGRGKYLHNEEEACDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKEKVDAGADYIVTQMFFDNKRFIEFVTKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A3E0HDQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum gallaicum|TrEMBL
MKVTEHLEKANGTSLFSFEILPPLKGDTIESIFKNIDPLMEFNPPFIDVTYHREEYVYKE
LGDGLLKKQVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPEKEGHGYASELVTQIENLNKGRYLDDDLQNSSKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKNGANYVVTQMFFDNEKYFEFVEKCREEGITVPIIPGLK
PISTKKQLNLIPYRFKVDLPDVLVKEVVNCKSNAEVRQVGVEWCIAQSKELQQKGVPILH
YYSMGRSTNIQQIAKAVF
>A0A124FEU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrotoga mobilis|TrEMBL
MKIIDLIKQSIKPILSFEIIPPNVGESIDPIFNVVDNLIDFSPKFINVTKHANEIEYVEE
NGEIIKIIKKKRPGTVGVSASIKHRYDIEVVPHLICTGFNKYQIEDILIDLNYLRIENIF
VVRGDKKRYTWKETDEYEHATQLVEQVTNMNKGIYTCPTKEHNPTNFCVGVAGYPEKHFE
SPNLEKDLDYLKLKVDMGAEFIITQMFFDIEYYKNFVNKVRELGIEVPIIPGIKPLGSKK
SLYNIPKNFHVNIPKAIVEEFEDAKSSQDEYIIGVKYGIKLIEQLLELGVPGIHIFTMGK
GKIVKDILNAFNGIF
>K9Z156|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacterium aponinum (strain PCC 10605)|TrEMBL
MTKLENAIASKEFIITAEVTPPKGGNPERMLEVARLLKDRVHGVNITDGSRAVLRMSSIA
SCVLLQREGIEPICQMTGRDRNSIALQADLMGAYSLGIRNILALTGDPLKAGDHPQAKAV
FELESVRLLKLIGQLNEGFDLNNKTLPDGNLNLFAGAAVDPQLKSWSGLQRRFEQKIKAG
AKFFQSQLITDFDKLDRFMNEIAKGCDRPILAGIFLLKSAKNARFINKNVPGVEIPEHII
NRLEKAENPLLEGMTIAAEQIKDAQQICQGVHLMAVKREDLIPQILDLAKIHH
>A0A0W8I0V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria polaris|TrEMBL
MTPRPIARPAPPSLSYELYPPRGAASAATLLRTIEELEPTRPDHVSVTYSGDEQRRDSSL
ALLDHLLARTSLRPLAHLTCVGSSRAELERTVATLVRRGVRGVLALRGDRDPEAAPGELR
HAGELVELVREVEQRHTASLAAGRLAVGVAAYPTRHPESPSFRHDVEVLLAKQRAGADFA
ITQVYFRPQRYERLVAAATAAGVTIPIVPGIMPVTDPGRLRTLCRLAGLAPHPGLAAALE
DASGPAERHRAGVAFAARLARAALDAGAPGLHLYTFNEHRAALDLLEHVDLPRAPHVPVP
LDDLLLPA
>A0A1H6IEX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus flavefaciens|TrEMBL
MHIKELFKDKTVFSFEVFPPKKTSPVDVIYSTLDELNDLHPDFISVTFGAGGSGNSRYAL
EIASKIKESGIIPMLHLPCINFTKSEIDAALDEAKERGIENILALRGDINPDIPPVNDFS
YASDLITYIKSKGDFDIAGACYPECHPDADSLVDDIINLRKKVEAGADHLITQLFFDNDN
FYEFREKAAIAGINIPIEAGIMPVVNKKQIERMVTTCGASLPSKFVRIMTKYEHNPEALR
DAGIAYAVNQIVDLVASGVDGIHLYTMNNPYVARKISEAVSGIIKT
>A0A3R7SL85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED50|TrEMBL
MNTPVISFEFSAPRDEQARNKVLTVRDKLSELDAAFFSITYGAGGSTRDGTLQTALALAS
TGTNTAPHLSFGGDDEVFIRDLLAQYQAAGIDRIVALRGDVPSGTGPGTHIYADELVTFI
RQESGDHFHIEVAAYPEVHPDSKSPQSDLDYFKQKVDAGADSAITQYFYNADAYFHYVDS
AAALGVDIPIVPGIMPITNVDTLIRFSDKCGADIPRWIKQQLIEYRGDKASLQSFATDLV
TSLCHRLLEGGAPGLHFYTLNQSLPTLRIFRQLSL
>A0A3C0Y5H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp|TrEMBL
MNVPVSFEFFPPKTPEGADKLRVTRQALYAHQPEFCSVTFGAGGSTQEGTFGTVKEILGE
RVAAASHLSCVGATKAAMRQHLATLQAMGVKRLVALRGDLPSGYGMGGEFHYASDLVAFI
RAETGDAFHIEVAAYPEIHPQAKSAEADLRAFAAKVKAGANSAITQYFFNADAYFRFVDD
VRRLGVNVPVVPGIMPITSSTQLMRFSDASGAEIPRWIRLRLQGYGDDTASIKRFGLDVI
TDLCDRLCTASVPGLHFYTMNQAAATTEIIRRLKPA
>A0A0G1YX83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kaiserbacteria bacterium GW2011_GWA2_58_9|TrEMBL
MKVTDLIKHSTKPFTSIEIIPPKKGTRMETLFGELEGLMRYKPAFMSVTSHAHERTIEEV
NGKKIERIKNKRLDTNAICIAAQSRFGVVPTPHVICRGFTKDETEDMLLTLRFHGLENVL
ALRGDGPPNDGEFANIYASDLVEQMQRMNRGEYLDPMENADKTDFCIGVAGYPEKHFEAP
DFDTDLKNLKKKIDAGSHFIITQMFFDNTAFYSFRDEIARRGINVPVIPGIKPLYKKQHL
EALPRIFYTKIPQAVQDSINRFEKEEDIYRAGIDSTIAQCKDLLAHGVPGIHFYSMSVAK
PTSDVLEGLK
>V5EQE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kalmanozyma brasiliensis (strain GHG001)|TrEMBL
MASTSAAATASSDPAHITSKIQAASARDAPFWSFEFFPPKTTQGLANLYNRIARMSANLD
PSWIHVTWGAGGTTGGKSLELAGRIQKGKLDPDVQLVQTEVKQIGSGSQQHIENVKGGEA
WEQGGADACDVCLHLTCTNVEKSSLDETLETAKRLGIKNILALRGDPPRGEEYWVAADER
FQHATDLVRYIRENHGDFFCIGVAGYPEGHADYVDRDVKRDLAYLKSKQDAGAQFIVTQL
FYDVEQFLGWYKDCRDIGITIPILPGIMPIQNYQSFRRMTNLCKVQVPKAILDAIEPIKS
DDAAVKEYGVSLSIHMIGRIFLETDVRGFHLCSLNLEKSIERILEGLDWKSDAGAQPEAD
ARLKGIPSHLHLERTKNQMLSDRTGTNTPKDFKVTTQEALARTLARTSSSYQVPETATWD
EFPNGRYGDSRSPAFGEMDGYGVSLKVPPQDALRIWGHPVTSVDISKIFASYLEEKIECI
PWCDAPLMNETLQIRDHLLALNRLGEQEGSGKGWWSVGSQPAVDGAPSTDPTVGFGPPGG
FVFQKAFVELFMSTADKDRLVERIDGLGANAQITYFAGNAKGEFESNLGEGEANTVTWAV
FPGKEIVQSTIIERDSFEAWRDEAFEIWGEWSLLFPKGSASRKLVEEIKEGRWLVTVVHH
DYKEREALWHFLAE
>A0A0S8CVW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira bacterium SG8_3|TrEMBL
MHISEVLRKHNPAISFEFFPPKTEQGFQELFRTISALMPLKPAYVSVTYGAGGSTRERTH
DLVVKLQRETDLTIVSHLTCVGSGREEIHQILSKYQGSGIHNIMALRGDPPKGSTEVPIP
SDGFQYASELVQFIKQQFPDMGVGVAGFPEGHPGTPNRLMEMDNLKRKVDAGADYICTQL
FFDNRDFFDFCERCEVVGIKVPIIAGIMPIVSRKGMARMSELALGARIPAKLLRAMDRAE
NDAYAERVGIHWATEQVVDLVDQRVKGIHFYTLNKSKATLKIYESLGIQSSESLQHMAT
>A0A3P3D6D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falsigemmobacter faecalis|TrEMBL
MSAPRISFEFFPPRSLDASFRLWETMKMLAPLRPGFVSVTYGAGGTTRQLTHEAVKAIGT
HFGVDVAAHLTCVDATREETLAIANSYADAGVSQIVALRGDPPKGADRFTAHPEGFADSV
ELIEALAATGKFNLRVGAYPEPHPEAREDLADVRWLKRKFEAGADSAITQFFFEAETFLR
FRDKCAKEGITKLIIPGILPIENWEGTKRFAARCAAQVPAHLDEAFTKANAEGREAALSV
QVCADLCRRLMAEGVEDFQFYTLNRPHLTLAVCAELGIHPQDQAAA
>A0A7S3JMS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureoumbra lagunensis|TrEMBL
DDASGFCEEVEMKIIDKITDCKNRNETFVSLEFFPPRSATGVANLEARWERMRDVVDPLF
TDITWGAGGSTSSLTMELTMKLKNIGLEPNTHLTCTNVKKEEVVDALQTCRDAGVKNIVA
LRGDPPIGQEKWEATDESFKCALDLVKFIRKEHGDFFNIAVAGYPEGHPDAILPTSQTFD
ELSQAEQSRCRIAPDGSLHVCNDAKYAEELAYLKAKVDAGSDIIITQMFFDCSTFAAFVQ
AARKIGISVPIIPGIMVLQSAAGFKKMTNFCNTRVPPTLAKQVDACGDNEQQIKQLGIEL
GVQMGKELIAQGVEGLHFYTLNLEKSTLAIIEKLGLTAKDRRKNKKVTYDKPIMTSTTWL
GLAAVAAWAYFILLRPNLRR
>A0A844H3C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus limosus|TrEMBL
MTTPAISFEFFPPKNLNQSFRLSETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETLQIVADYAAAGVHEIVALRGDAPQGQERFIAHPDGFASSV
ELIQAIAARGDMTIRCGAYPEPHPESPDTAADVAWLKRKSDAGATSAITQFFFDPDTFFR
FRDQCERAGITARIIPGILPIQSWAGTRRFAERCGTSVPRWADEAFAAAGKDGEAQLALE
TCVKLCEDLVAGGVDALHFYTLNKPELVQKVCAELDIRGKDGLSQVA
>A0A0E3P2T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina siciliae T4/M|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRYSVPLEDARHLKGLADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDFPSCGDHPGSKP
VYDLDSVQLIELVRKLDSGVDLAGNQLDGGTSFCAGAVSSIDPEKILQLIKLEKKVRGGA
DFIQTQAVYDVGVFEEFTEAVNHLEVPIIAGLIPLKSLGMAEYMNKNISGIHVPDEIMLR
MKEASSPLEEGLLIASETVKELTKLSRGVHIMPIGSHKNTPKLLSMAGISEI
>A0A7Y6NNK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schlegelella koreensis|TrEMBL
MKLPVPVSFEFFPPNTPVGAEKLSGVVAELATVDPEFFSVTYGAGGSTRDKTLATVAAIA
AMGQEAAPHLSCIGSTRESISEILGTYRAQDIHRLVALRGDLPSGTATAGEFRYASELIR
FIRETQGSDWFIEVAAYPEYHPQERYARRDLQHFADKVKAGADSAITQFFFNADAYFHFV
DEVRALGVTIPIVPGIMPIHSYAKIAQFAQRDGIEIPRWVALKMEGFLDDAAAVRAFGLD
VVEKLCRRLIDGGAPGLHFYTLNQSALSLELCRRLAG
>A0A844H4D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus limosus|TrEMBL
MDISPRQESPAAQLRPAAYTLEVTGKDIAQVEAARAVIPPGTPINIAFLGNEDHAQRVNA
ARTIRRCGFEPVPIISSRRLRSREDGDALLQALIAEAAPQRFILVGGDPSSPAGPFQDSL
ALMQSGIVQRHGIRRVGIVAYPEGHPKIAPEELWRALIWKVGFLRDMGCSVEITTQFGFD
AEAILAWLQRLRAEGIDVPVRIGVPGPASVGKLLRFARQFGVVTSAEIARRYGLSLTNLL
QRVGPERFFDRLAAGLAVQDLGQVRLHLYPFGGFDDGIQWINARLTGAGAEVFGRH
>A0A7C5SNC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanithermus profundus|TrEMBL
MRLTDKLGHGFVLTAEVDPPRGADPAPTLKQALILRGYVDAVNVSDAPMANLRMNSIMLA
HLIQHHTGVEVIPHLTARDRNRLALQADLLGAWALGVKNVLVLGGDPPERGDHPEARPVY
EFGAVGLVETIARLNRGENLSGGSLEGAPDLTPGVAVNPGAADLAAEAEKFWAKVEAGAR
FAQSQPVFCPETAAAFLDALGGRSPVPILWGVLPLRSLKMARNVARWTRVPEALVADLER
EGRAAGMRAAQHVLRELHAAGMDGAHLYPLGRVELLKEMLKPLGARLG
>A0A1G1DJU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium RIFCSPLOWO2_02_39_17|TrEMBL
MGFREAFDKKDFVVTVEIPPPKGANVVPGIDIAEKILGRVDGVNVTDNQRGIMRMCPLAF
SHLLKEMGHNPIMQVCTRDRNRLALQSDILGAGALGIENICIMTGDHPKLGDHPDAKPVF
DIDSIQLIKVVRELENGISMAGKKLDGSPRFFVGGVMNPFFEPFELELIKLNKKMGAGAE
FFQTQPFFDKESLERFVGQIKGIDTKFLVGISPLKSVKMVNFMNEKVLTRKIPENISKRI
ESAKDQTEEGVRIAAEFIKNIKDIVKGIHIMPIGIEQYLPYLLDEAEI
>A0A552B7F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis sp. M_OC_Ca_00000000_C217Col|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAVNITDGSRAVVRMSSL
AASAILYQHDIEPICQIACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A521GN39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MNTKIVDHLTDLSRLFNVNPARANEALNAQTLSGLQVSFEFFPPKTLEADAALSEVSSKL
ATLRPKFMTVTYGAGGTTKTKTHETAVAMQRATGIPIAAHLTCVGAPKSEINAVADAFWN
DGIRHIVALRGDMPGGAPYVPHPDGYPYTSFLIEGLKKLHNFEISVAAYPEKHPDAPSLD
SDIDALKKKIDAGADRAISQFFFEPVTFLRFVEKARARGIDKPIVPGILPIHNFSQVIKF
AQQCGTKIPDHMYSTFKALDQDPETRKLVSAITAAEQCKVLHAMGVRHFHFYTLNKADLV
YAVCHMLGLRAGGETASSATELAPARAGAIG
>A0A2E5KM03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSWLPGADEDATIIAAIELRHQGMTPVPHIAVRRIRNLASLGNLLRCLHDEAEVDEVLIV
GGNVAAPKGPFEAAVDVLESDVLLENGISRVGVGGYPEGHPAISGPDLLNALLRKQAVAD
AAGLEAFVVTQFAFTAVPVIAWLEYVRAAGLRLPVHGGVPGPARIGTLMRYARMCGVSSS
MKMFVRHGRGLASTARVSKPNRMVRDLAGYCAEHPDPGMGPVHLYPFGGLTRTADWVSKL
Y
>A0A3M1K0G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
GLKRIADFEISVAAYPERHPESPTLAADLENLKRKEDAGATRAITQFFFEADTYFRFLDH
ARAFGITMEIVPGILPVTSVAQVRRFAAFCGAEVPAWMDDLFEGLDDRPETRALIAATVA
GELCSRLHAGGVRHFHFYTLNRAPLTYAICHLLGLRPRKTGAAPDAGNHTDREDAA
>A0A2R4N1Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carboxydocella thermautotrophica|TrEMBL
MLQQKLAQGRQVLTVELPPPRGIAFQEVLELALAIKEKVTAYNITDNQRAVMRMSPVAMA
ALLLQAGLEPICQFTCRDRNRLALQSEILGAAALGVRNFLLLTGDHTLVGDCPGAKPVFD
LDSVQLLAAADNLRRGFALNGEPLQGVPDLFLGAVVNPAPELREMQIWKLQKKIRAGAAF
VQTQAIYDPGILADFLQEAGELGVPILAGVIPLRSARMAHFMNANIPGIQVPPAMIRALE
KATDPLAEGLAITVELIRELRTLVPGIHIMPVNTLRALPTLLARLEGEEHEG
>A0A537S7W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTDTGSERRSRLVGDGDINVSFEFFPPKTEKMEETLWNAVRRLEPLRPRFVSVTYGAGGS
TRERTHATVARLVRETSLVPAAHLTCVEATKADVDEVAKSYSQAGVRHIVALRGDPASGV
GTKYSPHPGGYRNAADLVAGLKQSGNFEVSVAGYPERHPESASLAEDLDNLKAKVDAGAS
RIITQFFFDNAHYLRFLEAARARGIWAPIVPGIVPIHNFKQVAGFAGRCGATMPSWMARR
FDGLDADPQTTHLVAAATAAEQVMDLVDQGIRQFHFYTLNRADLVYAICHLLGLRALASN
GPALAKEAINA
>A0A0F0LSY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium ginsengisoli|TrEMBL
MTSSVDSVPAPAPFSFELYPPRTAASEAALHETIARLAEVGPRFISVTYGAGGSTGGRSL
EVLRHIRATTDVEPLAHLTCVGNTYAGANRLIREFLDAGIRSFLALRGDPPAGTSEDDVY
LGDLESAAQLVQLIDRVQAERAPYQESGIPGMPGAARVDPRPRVDIAVAAFPNGHPRSRH
PREHIDALLAKQAAGATLAITQLFFHADDYVWFVDRARTAGVTIPILPGIMPITGPARLR
RVLQLTGEEIPADLAIALEVEPTAEGQREIGIAHAARLAEEVLAGGAPGVHLYAFNNHDT
VLSVLREAGILTAGASGPASTPVKESRR
>A0A349MKF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MISLELVPRDSVSLIEELELLRGNFREVDLINIPDLPRFAMRSWEGCALARRYFSQVVPH
IRARDIDPDRPLPMAGFLREHGIDQVLVVTGDVHPDVFFPQYTVRAVEVIRKFKREMPEV
KVYAAMDPYRSGFQEEIAYVREKLNAGAEGIFTQPFFDLRLMEVYGELMKGLNVYWGVSP
VTTVQSKGYWEKRNLAVFPSAFEPTEGWNLAFAHAAMAFAKCRGHHVYFMPINRDLKSYL
DGLFPR
>A0A0F5K398|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robbsia andropogonis|TrEMBL
MAAIEISFEFFPPKSEEGVAKLAATRAALREFHPRFMSVTYGAGGSTQQGTLDTVKAIAA
EGVEAAPHLSCVGASRESLTQTLDTFRAAGIRRVVALRGDLPSGMVDTGEFRYASDLVAF
IRQHAGNAFHIEVAAYPECHPQSRNARQDLKHFMTKVDAGADSAITQYFFNADAYFRFVD
DARAAGATLPIVPGIMPITNFSQLVRFSEMCGAEIPRWIVRRLESYGDDLPSIRAFGVDV
ISAMCRRLIDGGVPGLHFYTLNTAAATSDICRNIISA
>D7GZH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella abortus bv. 5 str. B3196|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A2E1YT85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MLKTKKISVSFEFFPPKNQVSIESLWTNIKRLEPLKPKFISVTYGAGGSTRENTHSLVKE
IKKKTSLEPAAHLTCMGTSYQEIEKIAEDYWNTGVRHLVALRGDVPKEIDGNKQNDFKYA
TDLIRFLKGKYDFEITVSAYPEMHPDSDSLEQEYDVLKKKIDLGATKAITQFFFNVNAYF
EFVDGALKRGINIPIIPGILPVTNCKRTLQFAKKMNCEMPLDLIEMFKGLDSDQETRKLV
AVTIVYDQCRKLIDGGIEDFHFYTLNRADLSFAICHILGIRTLG
>A0A257CW80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium PBB3|TrEMBL
MRLTDRTPISLEFFPPKTVEGADKLRVVRQKLYALRPEFCSVTFGAGGSTQEGTFNTVRD
ILGEGVPAASHFSCVGATKTTVRAQLATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDL
VAFIRAETGDDFFIEVAAYPEVHPQAKSPASDLQAFAAKVRAGANSAITQYFYNSDAYFR
FVEDIESMGLDVPVIPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQSFGDDVASIKSFG
LDVVTDLCEQLRAGGAPGLHFYTMNQSAATLSLCERLGLSPDAATA
>A0A537T3D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTEMTAATSQIENRPEPIAAIADFMAGFSLEATRPSAEEIAALAAIAPPATRVYLSAVPK
KPAQEAIEAAAQLRKAGFEPVPHLAARGFASARALNDFLARLSGEAGVVRLLIIAGDHEE
PVGDFRSAIEVIDGGALQRHDIREIGIAGYPDGHPRILQQDLDRALADKIRSAEATGMAV
HIVSQFCFDAQAIVQWIARLRDFGLDHPVRIGFAGPTNLATLLRYAKRCGVRASAQSLAR
QAGLLRQLFAMSAPDGLVRALAQARAQLHLADIAPHFFSFGGLLRTARWAEAVAQRRIAL
EADGGFRVEPPRAETIEAPAAAQ
>A0A724KZ48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Corvallis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIISGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A534IQP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MEDRPSRPIKSGGRLERVLIGKQFAVTAEVVPPASPDPSSLIASARKLKGSADAFNVTDS
PRARVHMASWAGAALLVREGLEPVMQIVTRDRNRIALQADVLGASALGVRNVMALGGDDP
KTGNEPDATAVFDLTTEAFIETLRNLRDKGVLHGGDPVGPRPPLFIGATANPFVGPIEDS
FVNLRGKAEAGADFVQTQAIFDLDAFEEWMHLVRKEWLHEKLHILAGVVPLKSLKAARFM
NEKVPGVVVPADVLRRIEKASDAKAEGLAIAIGVVEALKKIEGVRGVHLMAVNWDDVIPA
IVRGAGLHPRPSMT
>A0A816UFN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica napus|TrEMBL
MKVVDKIKSATEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNAICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIKSKYGDYFGITVAGYPEAHPDVIEADGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPVVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAFGIHFATEMCKKILAHGISTLHIYTLNMDKSAIGILMIL
GLIDESKITRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYGTLSDYQFMRPRARDKKLQQEWVVPLKGIEDVQEKFKELCLGSLKSSPWSELDGLQPE
TKIINEKLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TFMEKSKAFPSITYMAVNKAGNWVSNVGEADVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYFLVSLVDNDYINGDIFSIFA
>A0A854CSA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus epidermidis|TrEMBL
MSQFLNKLQNNVLVADGAIGTIFYSEGLDTCPEAYNLTHPEKVERIHRSYIDAGADVIQT
NTYGANFEKLKAFGLEHKVKEIHKAAVQIAKKAANEDTFILGTVGGFRGVKQDDLSLSTI
QYHTEHQIDTLVDEGVDALLFETYYDLEELKGIVVSTKRKHHIPIIAQLTASNTNYLVDG
TPINDALKQLVECGADIVGLNCHHGPHHMQRSFSHIELPDKAFLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIRYIKTSVKNLRPVVHKNVIPINKKV
NRKKDLNSKQSLTSKVKQGPTVIVELDTPKHLDTDQFFNNIGKLDDADIDAVTLADNSLA
TVRVSNIAAASIIKQRFNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEATKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEEVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITTHKEAIL
>A0A0W1KK45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trueperella bernardiae|TrEMBL
MATFPAGNPAAGTSPETEVERLVHKQVAGADFAISQFSWHAAEFTRFVELARAAGVTIPI
VPGILPPVETRRVLRTQELTGVVASPEILEALATAATPEEEERIGVRIAADLALELLDGG
APGVHLYTFNKAVPALAVMDLVAKEHHA
>A0A1G9R4S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Romboutsia lituseburensis DSM 797|TrEMBL
MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAANVTDFQSAVMRTTSLA
TCKLLKDVGLEPVIQMTGRDRNRIAIQGEMLSAGVFGINNMLALTGDHTVVGDHPQAKGV
FDLDVVGILQTAETLMKGTDLVGNQLKGSPEFYLGASVTPEYAPIEVQLLKMRKKIAAGA
KFFQTQAVYDIEHMREFRKLTKDMDCKILAGIVPLKSPGMAKFMTANVPGIFVPDDQIER
LRAAGKENWVSEGIKMAGEFIRQLIDEDLCDGVHIMAIGAEENVPAILDAAGL
>J3AWQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM49|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQADASLAVWKNLKLPR
>A0A653Q7C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. G8|TrEMBL
MASLAAARALLLSPLGPVARAGSNRDDVRVSFEFFPPKTDEAEANLWKAIRRLEPLNPAF
VSVTYGAGGSTRERTHRTVQRIIAETSLRPAAHLTCVEASRDEVDEVIAGYKTIGVDHIV
ALRGDPPGGSGIGGVYQPRADGYANATELTQAISRVGGFDVTVGAYPERHPESPSIDHDI
EVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLTRMCGA
CGTSIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRADLVYAI
CRVLGVRETKAVA
>A0A3D2SPX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter ursingii|TrEMBL
ITQFFFNPDAYFYFIERLEKEGITIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLA
AYGDDSASIKAFGHEVIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLI
>A0A482J3J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus metallidurans|TrEMBL
MARPLINPDKPRPVSSITDAYSLEVSAKDIAALTAAAPRMVPAATISIPYLPREDDDARL
AAARAVRRLGFEPMPHFSARRVSSLAELQSFVKRAVAEAGVERCFVIAGDPSTPMGPFPD
SSSLIETGVFEHSGIKVIGVGGHPDGHPVMSAADRWDVLERKCHSIKRRGMTPLIVTQFA
FDADIVLTWLKALRERGIEHPVRVGVPGPAGVTVLARYAALCGVSACASMWSKYGVSIGK
LFGTAGPDLFVDRLATGLTEAHGKVSLHFFPFGGIAQSVRWIEQYRARAEPLRF
>A0A2K9MT33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sporogenes|TrEMBL
MHIKELFNQKNLVFSFEIFPPKATSSVKTIYETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTREYIDSIINELKENNIENILALRGDIPKDKNIIGK
YNYAFELIRKIKENDNFGVAGACYPEGHIECESLEKDIKELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTEQKNINVPIQAGIMPVVNKKQIERIIKISGATLPKKFMKILDRYEYDKEA
MKDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARRITESTKSIFNSINKDIAV
>A0A7Y9H6C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides cavernae|TrEMBL
MTHPRDLSMGELLARGDRSFSFEFFPPKDEAGEQQLWQAISELEPFGPTFVSVTYGAGGS
TRDRTVAITERIARETSMVPVAHLTCVGHTTTELDAILDDLHEAGVRHVMALRGDPPDGP
GSPWTPTDGGLTYASELVALIRGRGDMRIGVAAFPEGHVDATDLEQDARVLKAKQDAGAE
FAVTDMVLRASDYAGLVERASAVGADFPIIPGIMPILSLRSMERMVEFSGRQLPEEVVAR
LAPLSDDPQALRTEGVAIATELCAALLDAGAPGLHFYTLNRSRATREIFANLRVTA
>A0A8H6A7C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus burnettii|TrEMBL
MHIKDKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAADGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSTF
IVTQMFYDTDIFIAWVKKCRAKGINVPIIPGIMPIQTYSAFIRRANWTKIHIPEDWLEAL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGLNHLHFYTMNLAQATQLVLEELKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIRDLSHIFVRYLEGQLNRLPWSDTPISSEANSIKANLIE
LNNRGLLTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLVPPYLLDELIARIESNE
DLTYHAISKSGELRTNTRDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHDATSPSRKLIQGLVDNWYLVNIVNNDFHNTSVLFELFKDLHVRDFDVEVTANIDSKS
QENGTADATEIAVKN
>A0A368NAL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloplanus salinus|TrEMBL
MSLTKSKPTGASSLLAKPRFELMPFDSFEGQMEQLPEGAEIAITASPQLGLDATVEWSEK
SAARGYTPIPHVAARYVRDKEHLDEIATRLTEAGVTDIFVPGGDREDPVGEFESAYELLV
ALDDLGHEFDEVGITGYPEGHDFLDDRTLAEAMDRKAPYATYVTTQLCYDPEAVVDWVEA
IRDRGIDLPVEVGIPGVMKYQRLLSISQKVGVGDSIRFLRKTSGIVGFVRQLVGSRGKYT
PDALVDGLAPYVDDPEYGIRGIHVYTFNQTADTEAWRRERLDN
>A0A0S6X288|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. MBES04|TrEMBL
MSTPIIHPNWARPAINMVEGYSLEMTAKDIESLREAAPGIAPETPIAVTFLPGEAFEARI
AAARLVRELGFEPMPHFSARRIVSEDEFREYLKAVTKEAGVKRCFVIAGDPSEPEGPFAD
SSALIATGAFEDAGITAIGIGGHPEGHPNMSDEECWSVLQTKCDEIEKRGMAPLIVTQFA
FDAGAVLSWLAELRKRGLSAPVRLGIPGPAGIKTLMRFAARCGVGASASVLTKYGISITK
LIGTAGPDKLVDQIEKGLTEEHGAVRLHFYPFGGLTKTVGWINDYAKSH
>A0A7C3GA51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfatator sp|TrEMBL
MEKVREALARKEFIFTFELVPGRGSRGKAYDQLVAFAEAAARGGRLHALSITENAGGHPA
LAPEVLGREIKALGLETIIHFSCKDRNRNQMESHLFAWDREGFHTILVMTGDFPRVGFGG
QAKPVFDLDSVQTLALISRLNQGYVIRNGQRLPPTSFFKGCVVSPFKRLEAEVMTQYFKL
ERKISAGADFVITQIGFDARKFDELLRYLRLRNLEIPVIGGVFVLDLPLARIMHRGRIPG
CRVTDELLAKIEAESEAPDGGLSARLLRAAKQVALLKGLGYAGAHICGPNLTYEQVEFIV
EKALELTDNWLEFVPEFTFAPEGTFYLFQKDPRTGLNTDDLTPRAPASSSPWHYVINRLI
HDNFFLPDGPLFSFTRRLFLSLADSPLAGMLDSLEYFVKKILFDCRSCGDCTLGELAFLC
PQSKCAKYLLNGPCGGSYDGWCEVFPGKRRCLYVQAYERLKAQGEEESLARGMVPPRDWA
LNGTSSWINYFSGRDHHRLRDKK
>A0A847ZYC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacteriaceae bacterium|TrEMBL
MDTSVSFPPATSAAVGNPTAAFLGRSTIEVTGKQIEKFPLLKDNLPAGSHVFIALIEAQD
LDAQITAAAELRKLGFEPIPHIPARFVRDEADLNARMSAFAEKAGVTTVLALGGGAPEPI
GKYDAAIQLMNTGVFQKVGIKRVGIAGHPEGNPDISKKHGEVALMQALKDKTAWLKANNM
GGFIATQFLFEAGPLALWASQLRDNGIDLPINVGVPGPATIKTLVKYAAMCGVGNSARFI
RKQALNITKLLTVSEPTEFVDQLAKLHFDKPELNISAPHLYPFGGFDKLFTWLKAQKG
>A0A6M1U6M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus sp. SYP-B805|TrEMBL
MTKKRDLRAYLQEHILVGDGAMATQLYQLGVPVGTSFEELCITNPQLVYHVHTAYYNAGA
RLLETNTFAANRDSLSRYGLENKVTRINRAAVTIAREAAKDDAFVVGSIGSIIAGRVRIK
PLEEYRDQFEEQAIALLHAGVDGVMLETFLDLEELLLAVEVIRSLTDVPVISQLATLEVG
RTRDGYTLTEAFRQLKEAGADIVGLNCRLGPAEILRSFESAVTPDHVLLSAFPNAGRLGL
SDGELAYKSSPEYFAESALRLREQGIHLIGGCCGTTPAHIRAIAQALSGMEPLARVNPDI
AVVERQGHVIQSVSQRHKPTIVEQVKEQHTVIVEFDPPKDLDIDDFLHGCCELHQAGVDA
ITMADNSLANVRMSNMALGAILKSRYGIDPLVHIACRDRNLIGQQSHLMGLHALGIDQVL
VVTGDPSRFGDLPGASSVFDVTSFDLIRMIKQLNEGISFSGRPLKQKAQFTVGAAFNPHV
RKIEAAVDRLKRKVEAGADFVMTQPVYDAETIRLIHDATKGIGIPVFIGIMPLTSWRNAE
FLHNEVPGIKLSPSALARMRNLQGEAGRQEGLAMAKELLDEAVRYFNGIYLITPFHYYQM
SVELTRYVHEITDSRTQSALRTVGLH
>A0A6M7TGK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium jarvisii|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVCRILNETSLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A7C7PP85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marine Group III euryarchaeote|TrEMBL
MRFRDKVRKPKRPVVAYEILPPREKDGTLNSYAERISSLLSQTHIDAINIPEVHEENARG
LRPVKNLERAEAREFGRLLQDNVGIEAIVNRVTVHNDLDYQKSWIKETFYDYDIENLILV
GGESSDIKYPGPSVNETSEYITRDLNAGRFDFFCGGITIPSRKIESVRLLKKGSNGIEFF
TSQVLYDGKKIKKMLKYYDDVCKENNVLPRRILLSFAPVSSKKNIDFLKWLGVEIPSQTE
KRLTNKKTSMSDESLEIASEILKGILNNNEKLGITVPIGLNIEHIMSYNFQSSIN
>A0A4Q7R235|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2569|TrEMBL
MANGLPSTRPGGAPTIRQLLASGDRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVSHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWIAHPEGLNHATELVELIRSLGDFCVGVAAFPDKHPEAASLETDAQVLAA
KAQAGADYAITQMFFGADDYFRLVDRAAALGCDIPVLPGIMPVTNIKQIQRMADLTGMAL
PVAVTDRLLAVEDDPAAVREVGVEIATELCERLLAGGAPGIHFITLNRSTATRQVFRNLK
ASVVS
>A0A1V4M3W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|delta proteobacterium ML8_F1|TrEMBL
MFDEKRPTVSFEVFPPKKDYPIETIYDTIESLKDLDPDFISVTYGAGGSTQNNTIEIASR
IKNHYGIESIAHLTCISSSRETIRTTIETLKASGVENILALRGDIPEALVKSGFKPAYPH
TVDLIEEIKKSRYFSIGGAAYPEGHVESLSRTSDIKYLKSKVDHGLDFLITQLFFDNRKF
YQFKESLDLLDIKVPVIAGIFPVVNLRQINHVQALTGTRLPSKFSRIIDRYQDKPEALRE
AGIAYAVNQIIDLLSSGVDGIHLYTMNQPMNTRKIMEPITTIRKTLTQK
>A0A1V5QXL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium ADurb.Bin341|TrEMBL
MSPVKSNLQAVLQAGKFAVTAEAGPPRGVRPEVLRDKARILKGWVDACNVTDNQTSVVRL
CSLAACKILQDEGQETVMQMVCRDRNRIAAQSDILGAAALGIHNLLCLSGDHQVFGDHPQ
AKNVFDIDSIQLLNIATRMRDESKFAGGKDIDGAPDLFIGASANPFADPFKIQVPRLAKK
VAAGAQFIQTQSIFDLEKFKEWMNGVRDRGLHEQTAILAGITPIKSLRMAEYMATNVAGM
DVPDAILERMRGVDKKEQKQEGIKIAVETIQQLREVEGVRGIHIMAIEWEEAVPEIVQQA
GLVRG
>A0A6C8RM45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILSVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>C0AUB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus penneri ATCC 35198|TrEMBL
MHKMFDGLDNDPETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
ELVQA
>A0A1F0TE08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC036D11|TrEMBL
MTTVHPALSYELYPPRSHASCDSLLKTITELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLALRGDIPPENARPLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAARLAGVEMPIIPGIMPVTSLTRLTKLCELAGLEVPRELAHRLETASDP
RELHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>A0A3D5MCB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwiniaceae bacterium|TrEMBL
MSFFHANQREALNQSLAELNGRINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASRDELRIIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKEVGEFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPGWMNSMFE
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAALVA
>A0A2S3XFV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREKNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFFTLQLGF
DAAKHQEAIHWMHRQASPKPMLACLMSLTHGRATMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALEARIEHWQTQLQSLEQWTPA
WHASWQMPGLPAVTFHPPQAGWRLGESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPLWATRAGAQVLHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A3R9YNW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas ginkgonis|TrEMBL
MSAALAHRLVEERPPLFAGASGDIDVSFEFFPPKTDRMAETLWQSIETLQPLQPRFVSVT
YGAGGSTRERTHATVERIARETTLPAAAHLTCVNASRDELDAIARDYWNIGVRHIVALRG
DPPEEGATYAAREDGYADAAALVAGLKQVAPFEISVACYPETHPQANCPDSDLDNLARKV
DAGADRAISQFFFSADAFFRFRDRVAARRIDVEIVPGILPVSNVSQTRKFAGQCGAEIPA
WMDAMFDGLDELPAARQLIAATIAAELCGQLYAGGVRHFHFYTLNRAELAYAICHLLGVR
AKKASVSA
>A0A2M8NWM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phototrophicales bacterium|TrEMBL
MSKQPILEFLKNGNTLLADGAMGTVLHQKGANLNACFEHLNITAPEMVQSIHAEYLLAGA
RLIETNTFGANRYKLSEYGLGEQVVEINTAAVQHVRQAIIQTNIPADAVYIVGSVGPIGL
RLRPYGKINPTDLRTGFVEQIRALSQAGVDAILFETFSDHNELLIAIDVVKSIRETDGVD
LPIIAQMTFAQDDRTLLGYSPARAAHELVKAGADVIGVNCSAGPSQIANILATMHQAMPN
ALLSAMPNAGYPQAIGGRVMYPATTDYFGEYAPTFKAIGARIIGGCCGTTPAHIAAMNVA
LQKPVKVEFPLQVTEINQEIESITPDNPTTLARRLMENRFTITVEIAPPKSYTVEKLVSS
ARLLREAGADILDVADTPAARMRMSPWAVSHIIQNQVGMETVLHFPTRGRNVLRIQGDLL
AAHALDLRNLFITMGDPTKIGDYPEAMDNFDIAPSKLIELIKHKMNQGVDLAGTSIGKPT
AFHVGCAVNMFADDLDHEVKLTIKKIEAGADFALGQAVFEPHKIELFLERYLAITGEHFK
LPVLMGIMPLYSLRQAQFLHNEVPGISIPDSLMKRMEDAGDDAPQEGVKIAQELLRAIRP
LMAGAYIIPAFGKYELAAEVIADMPIFA
>A0A0P7D8U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSTERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFFTLQLGF
DAGKHQEAMHWMSRQAMPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPMWATRLGAQVLHKVEHAVKHPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTALLTERLIPCIELETRHRSSWPQWFQAQTP
RQLSPQPAPRTQPES
>A0A8F8G6Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIREETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A6S6S1Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Thiotrichaceae bacterium|TrEMBL
MNTPSFSFEFFPPKTDKGIENLKTVRESLAELKPEFFSVTYGAGGSTQDCTLSTVIDIQQ
HSGIDTAPHLSCIGSSQKQIRELLDIFKNNDIKRIVALRGDLPSGMMDIGEFKYANELVE
FIRAEKGDYFTIEVAAYPEMHPQATNFQSDLMNFAKKVSAGADSAITQYFYNADAYFRFV
DSCAHIGIDTPIIPGIMPITNITQLARFSDATGAEIPRWLRKRLEGYGEDLDSIQKLGLD
FVTEMSDKLLAGGAPGLHFYSMNRVEPSLSIWNNLGLSER
>A0A2S3WW55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKAALREKHFVCVMEFVPKPSAERFAAMEAIMARGQLCGWPMTVAIGDRVGSPLDMS
PLDALASFSTPLPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGERP
VRYLESVAALLIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DASKHQEAIHWMQRQAAPKPMLACLMSLTHGRATMLEHVAGVTVTPSMHELLEAESKVSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGIHELKQLLALEERLEHWQARIHSLEHWAPA
WADCWQMRGLPIVAFHPPQGNWRKGESTVSASGKEKVRYHLLHGAHSLLFSRTNWLSKAF
GWAVRQPLWATKRGARVLHGLERAVKRPLIGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLAERLIPCVEVETRHRSSWPQWFEAQPP
RQLSPQPAPRTQPES
>A0A087BL82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. suis|TrEMBL
MHSPMFTLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPGLKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIRSLRAAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNAEPLFLGTQG
>A0A1T4M4X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium coprostanoligenes|TrEMBL
MKISEILKNNRVTVSFEVFPPKQWDKLENTKNTVKEMCKYNPSFMSVTYGAAGTTSGFTT
EIANEIKNCGVSPLSHLTCLTSTRDKIHQVVGELEDNGIENILALRGDIPQGFEFKDKQY
FKNAYQLVNEIKAMNPNLCVGAACYPETHPESKNRVEDIARLKEKVECGVEFLTTQMFFD
NEKFFNFYEMCQIKGINVPIIAGIMPITNANQIKRSIELSNSSVPPKFFRIMERFGDDPD
KMKQAGIIYATEQIIDLMANGFNNIHIYTMNKPDVAKAIMGGLSSIINE
>A0A3G2S8L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malassezia restricta CBS 7877|TrEMBL
MKGDDSSKITHKIARAKREGRVWWSFEYFPPRTPQGMQNLYDRIERMSQLGPEFVDITWN
AGGRTSDMTTQLVKTVHAYFGVETCMHLTCTNMPRSKIEVALREAKEFGCRNVLALRGDP
PACGSPWEPHAAGFSHAYELVQYIREHYGDYFTIAVAGFPEGHPEATGGPDVEMQHLKQK
IDAGADFIFTQMFYDLDAFVSWSRRVRATGITVPIVPGVMPIQNYGQFTRAVARFQAFVP
PHFHEALDPVKDDDEQVRVVGTRLVGDMCRQMLAHPDLDVHGLHIYTMNLERGSRMLLEY
LGLTPSVNQLNPLPWRPSLTPKRRDENIRPIFWANRAKSYVNRTDGWDEYPNGRWGDARS
PAFGDLGTMEPNLPVTQDEARALWGTPTSVEDLQRLFVRFCAGELASLPWSDAPIAKETK
TIDQLLVQLNERGFLTINSQPAVDGAPSTDPVHGWGPPHGYVYQKAYLEFFVSTHKLDEL
IARIEAHPQITYHAVNAQGDMRTNTTSDAPNAVTWGCFPHCEILQPTIVESMSFLAWKDE
AFQIGRCWAAQYEPDSPTRRLLEHVFDTYFLVNVVHNDFKRPHAIFEPFLTA
>A0A5C8U5R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. WL9|TrEMBL
MPDANSHRASRDGFRPIRVSIEFFPPKTDEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVKETSLKPAAHLTCVNATKEEIDEVVQSYWDAGVRHIVALRGDPADGVG
ATYKPHPGGYAQSCDLVAGIKKIGDFKVAVSAYPEMHPEAASMDADIDALKAKVDAGADQ
AITQFFFENDIYLRYLDKVRAAGITIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLENDPDTRRLVAAAVAAEQVVDLVDQGINDFHFYSMNRSDLVYAICHILGLRSQGTKV
AERKAAA
>A0A5B8NHQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euhalothece natronophila Z-M001|TrEMBL
MMSRFRQAVEAKEFLVTAEVTPPKGGNPERMLQVAQSLKGRVHAVNITDGSRAVLRMSSL
AASVVLLRHEIEPVCQVACRDRNLIGIQGDLMGAHALGIRNILALTGDPVKSGDHPKAKA
VFNLESVRLLKLIRKLNEGLDYNDKSLPDGELDLFAGAAVDPQSDSWSGLTRRFEQKVKA
GAQFFQSQMLTDFDRLETFMNEVATPANKPVLAGIFLFKSAKNARFIQKYVPGVHIPEEI
IERLEKAEQPLQEGIKIAAEQVQKARELCHGVHMMAVKKEEVIPEILDLAGVKPIDGVKL
PETARLR
>A0A0J7XTZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium barchaimii LL02|TrEMBL
MTAVAPPVSGRIAETPLFAGLPGDISVSFEFFPPKSEKMEEQLWDAITQLAPLDPSFVSV
TYGAGGSTRERTHATVSRIVRETSLVPAAHLTCVAASKAEIDEVVDQYWDAGVRHIVALR
GDPPPADGGRFVPHPQGYASAAELVEGLKKRRDFEISVAAYPEVHPEAVSATDDLDNLKR
KLDAGATRAITQFFFSTDAYFRFMDKALAAGITAPILPGIMPVTSFAAIRRMSGNTAIPG
WLETMFDGMDTRPGPRALVAAVAAADLCKRLYEGGVRDFHFYTLNRAEQAYAICQLLGLR
PKENAA
>A0A4D6XQ67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFESDLANFALKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1R3TXQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. DSM 25558|TrEMBL
MTKTEADRQTSGNFKLSFEFFPPKNADMDVQLWETVEELSRWNPDFVSVTYGAGGTTKAP
TLVAVDRMISVAGLSTASHLTCVDASKQEVHDVVEELRGIGVKHFVALRGDPSTGPGTAY
KPHPEGYENAAALVRGLREIDDFQISVSAYPEKHPESESTDVDIDMLKRKADNGATRALT
QFFFDNAMFERYMERVTKAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPAFLDERFAGY
DENPVERAKVAADVAAEQILDLQSKGINEFHLYTMNRAPLVNAVLENVGFRPLKQSAA
>A0A4V3AID5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFESDLANFAHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2N2YR35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-16|TrEMBL
MEKTIIQYLAEAKKPLFSFELLPPLKGHNFDSIQQAIDPLVKFDPAFINITYHQQEVVYE
NLPNNLMKKHTVRKRPGTVGISAAIKYRFGIDVVPHIICGGFTREETENALIDLQFLDIN
NVLVVRGDPQPGTRIFVPEPDGNEHALDLVKQITNLNKGIYLDADLLNTRSMNFCIGVAG
YPEKHGESPNMDSDLYFLKKKIQAGASYIVTQMFFDNQKYFDFVTRCREKGITVPIIPGL
KPFTTASQLTAIPKTFNVDIPVDLVKEVIKCKNNQQVRQVGVEWAIQQSKELYAAGVPVL
HYYTMGKSDNIEEIAKAVF
>A0A0J1BBV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutaneotrichosporon oleaginosum|TrEMBL
MKITDKLLAAEREGRPFWSFEYFPPRTAQGLQNLYDRIERMRNLGPEFIDITWGAGGKNA
DLTSSLVEVCQGTIGIETCMHLTCTEMPKEKVEWALKQAKSAGCQNILAMRGDPVAGSDV
WKPTPGGFMHAIDLVRYIHKNYPGDFCVAVAGFPQGHPETPLTPDGKHQEMLWLKEKVDA
GADFIFTQMFYDVDIFFQWVKDVRSYGITVPIVPGIMPIQNWQKFQTWVKRENIVVPQEW
YDVLLPVQGDDEQVRARGTKLVAEMCRAILDNQEAGIKGLHVYTLNLEKGARMLLEELDM
TPRREQVMPLPWRPSLTPSRRSETIRPIFWANRVQSYLSRTSDWDEFPNGRWGDSRSPAY
GDLDGYPVAIGTTAKEALELWGAPQTRAEINELFAKFCRAEVKKLPWSQNGASSETTVIT
DQLAKMNERGYLTINSQPAVDGARSDDKVHGWGPTGGYVYQKAYLEFFVAPELLSPLIRR
IEKDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIIQPTIVEAVSFIAWKDEAFE
LGCQWANLYPEGSPTRSLIRNIMDTSYLVNIVANDFKDGMAIFEPFLLDQPLANGV
>A0A096PDN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium pseudograminearum CS3487|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDAEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSVEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFNSIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLERLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAVYPEWEATGLEAGGRAEAVNTRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWDYPKTRQDINDLFVKHIQGELSAIPWSE
EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PANEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGSTEASPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNLIHHDY
VNRDALWEVLSS
>A0A3B3SYP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paramormyrops kingsleyae|TrEMBL
MVNQVQRVDGSFQASKSDSSGASNSGGESSKDSSRCSTPVLDADRTDRLRDKMRRRMESG
DRWFSLEFFPPRTSNGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCANQTKEQITGHLAKAKRLGLKNIMALRGDPVADVWEEEECGFNYAT
DLVKHIRWEFDDYFDICVAGYPTGHPEAESYEVDLKHLKEKVDAGADFIITQLFFRAESF
LKFVKDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITSVIEPIRDNDAAIRN
YGIQHAVGMCRVLLETGDVPGLHFYTLNREVATMEVLKQLGLWIEDPRRPLPWALSANPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDD
LLKMWGEELMNEESVFEVFTNYITGQPNHCGHKVMCLPWNDDPLAPETNLLKDELEKVNR
RGILTINSQPNINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVQGKNTTNAPDLQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFGLWIEQWA
KLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLDSCLSQVIDDMFELLDAPLEAME
>A0A833L8H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beijerinckiaceae bacterium|TrEMBL
MNAFPIRSSRQVQGKPLGISFEFFPPKNDAMAESLWASVERLAPLSPRFVSVTYGAGGST
RERTHQTVKRILDETSLKPAAHLTCVAATKAETDEIIADYWAMGVRHIVALRGDPVTGLG
TPFVAHPEGYQSSADLVAGIRKIGDFEVAVSAYPEKHPDSPNFEVELDLLQKKVDAGATR
AITQFFFDNDHYFRYLDKVRKRGIGIEIVPGILPVQNFKAAAGFAKRTGADVPEWLAARF
EGLDDDAETRRLVAAAVAVEQVYDLLDRGVSEFHFYTMNKADLVFAICHMLGLRAE
>A0A6V8H8Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces cellulolyticus|TrEMBL
MHVGQKLQEQAATGRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRS
ELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALEAAYNAGCTNILALRGDPPREQEK
WEAAEGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNSDVDQLIDHLKEKVDAGSTF
IVTQMFYDVDNFLNWVDKCRAKGINAAIIPGIMPISTYDAFMRRSNWTKIRIPPDWLEKL
EPVKADDAKVREIGSKLVAEMCRKLLASPQIHHLHFYTMNLAQATRLILEELKLLPSEEA
PLHKPLPWRRSLGLRRRSEDVRPIFWRNRNASYIARTADWDEYPNGRWTDARSPAFGELN
AYGVRLKGTNEQNIKLWGAPKSIKDLSDIFLRYLNGKLERLPWSDSSVTPETSDIHNELV
DLNKRGFLTINSQPAVNGVKSTDPVHGWGPRNGFVYQKAYLELLVPPEHVDELLRRIEKN
PDLTYYCVNKTGELKARSDEGPNAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQLGDDW
AKCHPADSPSRKLLQRVMDEWYILNIVNNDFHKKDDIFRLFDGLVIKDFETEVTGTAPVV
ANGTN
>A0A7H8LYU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. NAK00032|TrEMBL
MRRVRPDRPPTVRELLAAGGRSFSFEFFPPKTDKGARNLWRTIRELESLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVDHSQAELRNLVGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPDGVEYAADLVRMIRSYGDFCVGVAAFPYKHPRSPDVGSDVRYFVEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDVPILPGIMPVTQVSTIERSEQLSGAPFPPEV
KARFDAVAHDPEAVRRLGVEYAAELCRELLEQDAPGIHFITFNKSTATREVYSLLGAEEY
GARGSVPPMTA
>A0A7L4ZBP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HF10|TrEMBL
MGTGLLDDFSLEMTGKDVPALEEARGSIPRGTRINVTFLAGEDHATRLAAARAVRRLGFV
PVPHISARRLPSRAALEEFLAGLAEDGTAADVFVVGGDPARPEGPYEDALAVIRTGLLER
YGVRHIGISGYPEGHPAISGPALWSALTDKAAAIGAGPFTGDVITQFGFDADPVLDWLAA
VRARGVDLPVRIGVPGPAGIRRLVGYATRFGVTTSASVARKYGFSLTNLLGTAGPDRFLH
ALGERYDPARHGVVKVHFYTFGGLRATAQWVGAFRERAR
>A0A5B0BLQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. ANT_H38|TrEMBL
MNLLETMKERILIGDGAMGTLLYSHGVDLCFEEMNLTHPDQVLHIHQAYIEAGADIIQTN
TYGANYIKLARYGLEDSVKKINKAAVQLAKKAAGKNTFILGTIGGIHGSRTSIGTKEEIK
RSFREQLYCLLLEGVDGLLLETYYDFDELTTVLKIAREETDIPIITNVSMHEAGVLQNGL
ELADALQQLEELGADIVGVNCRLGPHHMLESLETVPLMKRALLSVYPNASYPGYKDGKLF
YENEPEYFERFAMNFRREGASLIGGCCGTTPEHIRALVKGLTNREPIQEKFVEKKEAEVE
IIESTPTESKLPTLLETVKKRHSIIVELDAPKHLNTSQFFEGAQALKDAGVDAITLADNS
LATPRICNASMASLVKQNIGATPLVHITCRDRNLIGLQSHLMGLHTLGITELLAITGDPT
KIGEFPGATSVFDMTSFELIQLIKQFNEGISKSGKSLQQKTSFTVAAAFNPNVRHLDRAV
ERLEKKIEAGADYFITQPIYSTEKIIEVYEATKHIEAPIYIGIMPLTSSQNAEFLHNEVP
GIKLTDQVRARMALSDGNREQSTREGLEVSKELIDVALEHFHGIYLITPFMRYDMTVHLT
EYIHSKVDAIVAGEVVRTESIVY
>A0A7L5XYM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoblastus sp|TrEMBL
MNASLASRAPQRLSRHSSRDLRVSFEFFPPKTAEMETSLWEAVRRLAPLRPHFVSVTYGA
GGTTRERTHATVSRLVSETTIRPAAHLTCVGASRGEIDDVARAYLDAGVRHIVALRGDPP
TGIDAPYAPHPQGYQSTPELIAGLKKIGDFEITVSAYPERHPQSPDLLHDIELLRRKVDA
GASRAVTQFFFDNSLYYRYRDLASAAGISIPIVPGVVPVQNFKQTASFARRTGASVPDWL
AQRFDGLDDDLATRRLVAAAVCAEQVLDLIDHGVEDLHFYTMNKADLVRRLPSHRHAAGF
DRPGKGRLIMTKRDTPLLLAAAARQRILILDGAMGTMIQKLSLTEDDFRGERFRSWPSDL
RGNNDLLSLTAPDAIRDIHLRYFRAGADIAETNTFSSTTIAQADYGMQALAYELNEASAR
LAREAADIAEKEDGRPRFVAGALGPTNRTASISPDVNDPGYRAVSFDDLRLAYAEAARGL
IAGGADLLIVETIFDTLNAKAALFAIDEVFETGVKLPVMISGTITDLSGRTLSGQTSVAF
WHSLRHVKPFSFGLNCALGAKEMRQHVADLSRVCDTLVCAYPNAGLPNEFGLYDESPEFM
ASLVGEFADSGLVNILGGCCGTTPDHIRAIAERVKGVAPRVVPTIAPQLKLSGLEPFTLT
SDIAFVNVGERTNVTGSAKFRKLIKNGDTAGALAVALDQVEAGAQIIDVNMDEGLLDSQK
AMVDFLNLVASEPDIARVPVMVDSSKFEIIEAGLKCLQGKGVVNSISLKEGEEKFIHEAR
IVRRHGAAVVVMAFDEHGQADTQERKIEICARAYKVLTEKVGFPPEDIIFDPNVFAVATG
IEEHDNYGVDFIEATRAIRGQLPHAHVSGGVSNLSFSFRGNEPVREAMHSVFLYHAICAG
MDMGIVNAGQLAVXRKIDPELREACEDVVLNRRKDSTERLLALAESSRAAAEARAKDLTW
RALPVDKRLEHALVNGVTEFIDADVEEARAQAKRPLDVIEGPLMSGMNVVGDLFGAGKMF
LPQVVKSARVMKQAVAYLMPFMEAEKSGQRQSAGKVLMATVKGDVHDIGKNIVGVVLACN
NFEVVDLGVMVPAAKILETARAEKADVIGLSGLITPSLDEMCFVAAEMEREGFDLPLMIG
GATTSRVHTAVKIHPNYARGQAVYVTDASRAVGVVSSLLSKEGKADYIAGLRAEYAKVAE
AHARAESDKQRVTLERARANALAIDWADYTPPKPRXLGVRSFEDYDLAELVESIDWTPFF
QTXGLKGRYPAILDDEKQGEAARSLFADALAMLKRIVDEKWFRPRAVIGFWPANAVGDDI
ALYADETRETPLATFFTLRQQLTRRDGKPNLALADFVAPKATGKADYIGAFVVTAGPEEE
EVARRYERANDDYGSIMVKALADRLAEAFAERLHERVRREFWGYAPDENLTNAQRIAEEY
RGIRPAPGYPAQPDHTEKATLFRLLDAERAAGVALTESFAMTPGSSVSGLYFAHPDAYYF
GVAKVERDQVEDYAARKGMTVNEVERWLGPVLNYDPTRYRVAAAE
>A0A2S5CSS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylovulum psychrotolerans|TrEMBL
MHTQKHHPQLFSFEFYPPKTHEGTASLQLVQSQLAERQPDFFSVTFGAGGSTRDKTFDTV
VDIQTKGIAAAPHLSCVASTKHSIRTILQDYQDNGISKIVALRGDLPSGMMSAGEFRYAN
ELVGFIREETGDHFQIHVAAYPEVHPQALNATEDFKNFKRKVEAGANAAITQYFYNAEAY
FYFIDNCAKHGIDIPIVPGIMPISQYTQLFRFSEMCGADIPRWMRKKLESYGDDRASVQA
FGLELVTELCQRLLDNGAPGLHFYTMNQSALTLAILDGLR
>A0A4R7GGI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia rhapontici|TrEMBL
MSFFHANQREALNQSLAEISGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRAIAQDYWDNGIRHIVALRGD
LPPGGGKPEMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMTSMFE
GLDNDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGAQIIA
>A0A0L7C8C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium breve MCC 1454|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQAVGEFNHASDLV
SYIRSVKPDLKVFGACYPEGHYQADTIDQDIENLKIKVDAGATHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A2P6MAM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenimonas caeni|TrEMBL
MTPISLEFYPPKNDEQRAQLDRTARKLKAYSPEFVSVTFGAGGSTLSYTPETVRGLRADH
GLDAAPHLSCMGGTRAELRELLKLYRALGCQRIVALRGDLPSGMARMGEFRYASDLVAFI
REEHGDHFRIEVGCYPETHPQAEDALADLRHFKAKVDAGADSAITQYFFNADAYFRFVDD
VRAAGVGIPVIPGIMPISNFSQLRRFSEACGAEIPRWMAKRMQAYGDDADSIREFAADAV
AAMCRRLLEGGAPELHFYTLNLARPTEAVLSRLA
>A0A0H4BGU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. (strain WH8020)|TrEMBL
MSSALQSSLKAGTVTITAEVMPPRGGDASHVLEMAKGLKGLVHAVNVTDGSRAVMRMSSL
AVARLLLDEGIEPVLQMACRDRNRIAIQADLLGAHALGIRNLLCLTGDPVRAGDQPKARP
VNELESVRLLQQVTAFNRGDDPVKGDLADGPTDIFAGAAADPQCASWSGLIRRMERKKNA
GARFIQTQMVMDAAVLERFCREIAEPMDLPVLAGVFLLKSARNAAFINRMVPGACIPDRL
IARLEAAPDPAAEGIQIAAEQVQQYLGVAQGVHLMAIKAEERIPAILKRAGVSLPG
>A0A3E0LPY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa TA09|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAAFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>A0A367QHI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. ATCC 43529|TrEMBL
MHHTHSPTAFRRAVQAGEFLVTAEVAPPKGGDPSHMIKMAATLKGRVHAVNITDGSRAVL
RMSSLVASIILLQNGVEPICQIACRDRNRIGLQADLMGAHALGIQNILALTGDPVKAGDH
PDCKAVFDLEAVRLLQVIRKLNQGVDCNDKPLTDGSLDLFPGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFECLEKFMDTIAAGYKKPILAGIFLLKSAKNAQFINKCVPGVN
IPQHIIDRLAKAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIAPILDLAGVATV
NQLVTR
>A0A2N0MKB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G9|TrEMBL
MDEGADFLVSQLFYDNTDFFKFLDRAEKAGINVPIIPGILPILSTGQIRRFTALCGAKLP
AQLDQQLEKYADDDDAARELGVEYASRQVRELWDHGVPGVHFYVLNRSYSVSKILQNLAL
PGH
>A0A1E4MCV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. SCN 66-18|TrEMBL
MTTSYDQLREARTALDTPLFAGLPGDIRVSFEFFPPKTDALMTQLWDVVTTLAPLEPQFV
SVTYGAGGSTRDRTHGTVARIISEARLPAAAHLTCVDASKAEIREVAEGYWEAGVRHIVA
LRGDMGAPGVPFTPHPEGYANAAELVAGLKAIAPFEISVAAYPESHPDSPSVQADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAAACGAA
IPAWMDGLFEGLDTHPASRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPGRPALEKAA
>A0A4T0VA10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. GY 10113|TrEMBL
MAVGPGRSLGELISAGERSFSFEFFPPKDEVGEQQLWSAIRALEPYRPTFVSVTYGAGGT
TRDKTVAITGRIARETDLVPMAHLTCVGHTRAELEGILDAYVAEGVSHVMALRGDPREGP
RAEWTPTPGGLNHALDLVELAHARGFRVGVAAFPEGHPSAESLDVDADVLVAKARAGAEF
AVTQMFFRAEDYFSLVERVRARGVDIPILPGIMPILNLAAIRRQGELIGTSVPDDVVARI
TAAGEDRAAVRAAGIRLAAELCDDLLAGGAPGLHFYTLNRSKATLEIFEALRITV
>A0A3A9SN63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. XB500-5|TrEMBL
MKVSEIYKSGKKTLSFEIFPPKKDEALKNIDATLEVLTELKPDFISVTFGAGGSSNRNKT
IDIAKKIKHEYHVEPVVHLTGLQYNKNEIDEFARVMKDEGIENVLALRGDRNPQLVEKDD
FKHASDVIKYLKEKYDFCLLGACYPECHPESESRVSELKNLKKKADSGASALLSQLFFDN
DKFFNFYDECRIADINIPIIPGVMPVINAAQIKRMITMCNASFPERFQKIINRYEDNKEA
LFDAGMSYALSQIIDLLVSDIQGIHLYTMNNPLVARRICEGIRNIV
>D7IH24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. 1_1_14|TrEMBL
MRVIDLIHNSEKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLFWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEVLKCKNDKEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A8G0PT38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MPLQYSFEITPNIDRVNLDGLLNLNPEFISITDRNHDIDNLLQSIQIADYIHANSSVDVV
IHLTGIDKDKKRVQEMIDLMQQHDIHSVLALRGDKLSQNDTAVTFPHADRLVEFIKQQYP
HVNISGTCYLNSSDEEIKWLRQKIEKGCTNLISQFSFDVSDYVDYLNQIQIDTPIWFGIM
PVIGKSQTQQMLELTHSTAPDELNALMNQHDDEFGEDGVQYTAGMINKIKQAGAIHIHLY
SLNNAENTEKIINKI
>A0A6M0LN02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecochloris sp|TrEMBL
MLVKEILNSATGPVFSFEFFPPKKTEDWSKLFHTISELIPFNPSYVSVTYGAGGSTRSRT
HDLVTKIQRETGLTVVSHLTCICSGKKDVAEILEDYRTQGITNVLALRGDLPPGSTSYEE
ATKDFPHAVDLVKFIVENFPEIGVGVAGFPEGHPQTPNRLKEIEYLKAKVDQGADYIVTQ
MFFDNRDFFDFVGRCSLAGINVPIIPGIMPVTTKKGLIKMSELALGARIPAALLKKVLEA
PNDEEVAKTGIEWATEQTRELIENHIRGIHFYTLNNAEATRKIFTNIADRTRA
>A0A8H7UFB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mortierella isabellina|TrEMBL
MKVIDKIKKAEEEGRVYWSFEYFPPKTQQGVVNLYDRMERMYRYGPEFIDVTWGAGGVSA
DLTSEIVSTAQSVYGLETMMHLTCTNMPREQVDTALKLAKECGCQNILALRGDPPRGQDT
WESCEGGFQYAEDLVKYIREQYGDYFGIAVAGHPEGHIDNPSKEDDLMHLKAKVDAGADL
IVTQLFFDIEMFLDFVKRCRDIGITCPILPGILPIQNYNGLKRVISFNNNYVPQKIWDDL
EAIKEDDAAVKDYGIELAVSFIKRMLEEGIKGFHIYTFNLERSTRLILEKLGYSAPKENI
KPLPWNPSLHAKRTKENVRPIFWKNRTKSYIQRTESWDEFPNGRWGDSRSPAFGEIDGYG
VNLKYPTAECLQMWGKPTSFDDIATLFAKYCKGTLPALPWCAQQLDRETEIIRQRLSAIN
LLGYLTINSQPAVNGVKSSDKTYGWGPKNGYVFQKAYLEFFISPEQLDVFIRKINTNPEI
TYFAVNNNGDLRTNTQSDTPNAVTWGVFPGKEIIQPTIVESAAFMAWKDEAFELWQQWAY
IYEQDSDSAKLIQDIHDNWYLINIVNNDFQDEAGIWRYFDLEIDGEISRKLRRLSAGSDD
D
>A0A0S8CY65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium SG8_35_2|TrEMBL
MNFFKELSISSPFPICYNLLPHYASAGQDYTALKKDVTAAIADGRIKTFFLADRPLHHHD
FSSLHLAEDILAAGGEPLVSLSLTFHDRHTAIDKLQEYYRAGVRHFLFVSGDYPARTDDT
RENPVFDIDSVQLLMLLADLQEKGNIVKGCVVSPFKTYESEQIWQYEKLRRKISLGADFV
ITQLGFDIRKFDELVRFCALHKINAPLMANISIADMQTARLIQARGIPGVKIPGSLLHAL
HGELSDRQKVIVRTAMILAAVKGIGYHGALIGNQASEFADVQQILDKEEALQPDWQNFLD
ELDFSGPETQFYYFQKNPHNGLNSSEPAPVALKHFPSPTYSFSYFVDWLVYVPQGPLFKL
TGRFCHFCSTRKFWYTFLWLLEYISKGLLYGCNMCGDCTLYACGFLCYQSGCPKKMLNGP
CGGSSEGYCEVFPEKKRCYWVKVYHHMKGVKQDVTFVAPPIPARDSALHRTSSWINFFLG
KDHRKMNFDDC
>A0A0H3E1F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus atrophaeus (strain 1942)|TrEMBL
MGLLEDLKHQVLIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHEAYVQAGAHIIQTN
TYGANYIKLSRHGLEDETKKINKEAVKIARASSGGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAQEVLKIARKETDLPIVLNVSMHEQGVLQDGSP
LSEALRSLVGLGADVTGINCRLGPYHMIEALTEVPIFDDAFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSAIEFRKQGARIIGGCCGTTPSHIRAMADAVGGLEPITEKEVKVRAQETIS
IQHERTEPGLDEIASQKRSIIVELDPPKKLNFEKFLSAASELKEAGIEALTLADNSLATP
RISNVACGALLKQQLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLNDILAVTGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGRKTNFSVAGAFNPNVRHLDKAVKRLE
KKIDCGADYFISQPVYSEQQLVDIHNETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIREKMALAGEDKQKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
KKDEKRENVFLH
>A0A6G6X5H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nordella sp. HKS 07|TrEMBL
MEEQHRGPAAPYALEVTGKDIAQLEASQADIPAGTPVNIAFLGNETHAQRITAARVIRAC
GFEPVPIISSRRLLSQQDLDTLVSELIIEVRPKRFLLVGGDPASPAGPYPDSLELLRSGV
IERHGIRHVGIVAYPEGHPRIADAALWEALKWKLSFLADAGCSVEITTQFGFDADTVLRW
IEQLRHEGFDTPVRIGVPGPTDVGKLLRFARQFGVAASAGIARRYGFSLAQLVHRVGPER
FFERLLHGMEKRDVGAILYHLYPFGGIADGVRWMNRHAVSVTA
>A0A7V6UPR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillales bacterium|TrEMBL
MGFLQDLQNRILIADGAMGTLLYSYGVDFCFEELNLLQPDRITQIHETYIKAGADVIQTN
TYGANYIKLGRYGLEDQVKDINIAAVRLAKKAAKENTYVLGTFGGIRGIKKSAATIDEIK
RSFREQLYSILMEGVDGLLLETFYDFDEIKNVLEIARKETDLPIISQVSIHEVAVLQDGT
PLRLALKQLEDLGADVVGLNCRLGPHHMTQAFEEVPLPKKAFLSAYPNASLPDYVDGRLI
YESDSEYFGECAVNLRNQGVRLIGGCCGTTPKHIKAVSERLKGLTPITHKVIKMKDHENT
ITVTAKPTQPHLHEMVTKERSVIVELDTPKTLNTAKFIEGAKALKEVGIDALTMADNSLA
SPRISNMAMAAIVKNEVGIRPLVHITCRDRNLIGLQSHLMGLDALGIDQVLAVTGDPTKV
GDFPGATSVYDLSSFELISLIKQFNEGMTFSGKPLQKKTSFSVAAAFNPNVRHLDKAVKR
LEKKIEHGADYFITQPIFNEQQFLQVYEETKHITKPIYIGIMPIVSSQNAEFLHNEVPGI
KLTDDIRRRMASCGADREQAAIEGIAIAKSLIDIAFDLFKGIYLITPFMRYEISVELVQY
LHARNKSTAARN
>A0A840A545|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium haematophilum|TrEMBL
MSPHETALGPVARAAAGNTRRPSVSFEFSPPKTPEAEESLWEAIRRLEPLNPSFVSVTYG
AGGSTRDRTHRTVVRMLKETTLKPAAHLTCVEASRAEVDEVVQAYWDAGIRHIVALRGDP
PGNIGGVYVPRADGYLNATELTAGIKAVAPFEVSVSLYPQIHPESPSIDHDIDVLKAKID
AGATRAITQFFYDIDAYLFFMDKLRKAGVTIPVSPGIMPVSNYKGLKKMAGPVGIPLPAW
LGNLFDGLDKDPETRKLIAASVASEMCVRLAEEGYSDFHFYTLNRADLVYAICRVLGLRE
TPTEPAEAAA
>A0A7J5CMP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. ALFpr18c|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTEAGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATDTTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPEGVDYAEDLVRLVRDSGDFSVGVAAFPYKHPRSADVASDTAHFVR
KCRAGAEFAITQMFFEADDYLRLRDRVAAAGCATPILAGVMPVTQIGTIERSVQLSGAPF
PPALAARFERVAHDPEAVRQLGVEQASEMSRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARA
>A0A2L2WR21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. MGM2|TrEMBL
RLRRRPGTVAVAAAIQNEYHIPVVPHILCSGFTREETEYVLLDLQFLGIENLLVLRGDKA
KEDSHFKPTPDGYAHTTELQEQINRFNAGEFVDGTPVKEPGRPFSYGVACYPEKHEEALN
LDTDFAWFRRKVELGADYGVTQLFYDNTAYFRFLDRVREAGLDVPVIPGIKPFTKLSQLQ
TVPKTFHCDFPPELAEEALKCRTDEQARQLGIEWTVAQCRELMSRGVPSIHFYTVGATDS
IAEIARRIY
>A0A1E4I2H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. SCN 72-86|TrEMBL
MTTGPAALCPKRMRFGPCGGVRADLSCEVGPVRCPFGTLDDPVPWDGPHPPRRPEPTLLA
TSPVVLTDLTLPPFDRRGLARVVRSLAGTCDGLLVGEHHNRPDFPPTQMAGLVRDAGGAP
VVTLTCRDRNRVVLDQELAGLAALAGEGPAAVLCATGDARAAGMRPEVTQVFDLDGTALT
SHAAAAGLAVGVPESPEAPPLRLRPGRLAQKQRAGAQFAVLNPVTGPARLAVFAGRARAA
GATLPLVAGVAVYTDERSAKVLSAFPGLHLDPDRVTTVLSAPDPVEAGIAEAVEQARALL
AVDGVVGVNLSGLASSNGPLEGAAVKAAVGRALKDAA
>A0A1C6NAS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WMMB 714|TrEMBL
MAIGISATRTDRTTTVRDLLATGQCSYSFEFFAPKTEKGERSLWNALRRIEAVSPTFVSV
TYGAGGSSREGTVRNTERIATETTLTPVAHLTAVNHSRSELRNVIGQYADAGIRNVLAVR
GDPPGDPMGDWVKHPEGLTYASELVELIKESGDFCVGVAAFPEMHPRSDDWDTDVRHFVN
KCRAGADYAITQMFFRAEDYLRLRDSAVAAGCETPIIPEIMPVTNVKQIERFAELSNATI
PTEMAERLRSVEDDPAAVRSVGIECATELCARLLAEDVPGLHFITLNNSTATLEIHQNLG
LHERS
>A0A381EG24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter upsaliensis|TrEMBL
MCSFSFEVFPPRRNETIKNLDAILEDLGRLSPNFISVTFGAGGSINSKNTLEVASLIQEK
YQIPSIVHLPCIHSSKEKITAILKECKQRGLNKILALRGDVCEGLEKSKDFSYANDLISF
IKKQENFEIYAACYPEKHSEAKNIIEDIHHLKNKVNVGTDKLITQLFYDNEDFYAFKQNC
ALSGIKVPIYAGIMPITNKRQILKISQLCGAKIPTKFTKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKTKAAIRIYEAVKHLPKEENEAKNVL
>X6F4F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNHC229A00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHQVDAVIQEFTDMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEVAGS
AAA
>A0A3D9DJL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium elymi|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTPGGHASAMDLVHQINDLGRGKYLHNDEKACDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKEKVDAGADYIVTQMFFDNKRFIEFVTKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAIAQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A7J9YTV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRVDELLASQRPVFSVEFYPPKTEAGVANLFETVAALGPLEPDYVSVTYGAGGATRDGTV
EIAERIKREHGLEVMAHLSCVGETRDGLTAILDRFRGIGIENVLALRGDPPRGETDFSAP
EDGLASAAELTGFITDSYGFAIGGACFPEVHPEAESPEADLDYLKTKVDAGARFLITQLF
FDNRAYFDFVAAARERGIDVPIIPGVIPIASFGQVARICDLCDASIPAELERSMESLGGD
EEAEALLGVAFAARQCEELLAAGAPGIHFYALNRAPGTRAVLAALRTSRPWERVGAPAPE
HVAAPAAGPGPGG
>A0A1V0B3R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas phragmitis|TrEMBL
MSTHNKAPVSFEFFPTKTDAGHEKLIATAHVLAAHNPEFFSVTYGAGGSTRDRTLNTVLQ
LDGDVKVPTAPHLSCVGDSKDDLRSLLNQYRDAGIKRIVALRGDLPSGMGQASGELRYAN
ELVEFIRTETGDHFTIEVAAYPEAHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FHFVDRVRQAGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSDSIVA
FGTDVISDMCQRLLDGGAPGLHFYTLNQAEPSLAVWRNLNK
>A0A2R4KKF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella serpentiformis|TrEMBL
MERVIDLINKSRGTAFSFEILPPLKGNSIQSVYRVIDKLRDFDPKYINITSHHSEAIEVR
GTDGMVRTVNLRKRPGSVAIASAIQNRYGIAAVPHLVCKGFTKDETEYGLIDLNFLGVNN
LLLLRGDVKRLHEPDNAEIYHDHATDLQLQVNNFNRGIALDGSPITDIETPFSYGMACYP
EMHEDALSMDDDIRYAKLKVEQGAEYLVTQMFFDNAKYYAFVDRMRAEGVTVPIIPGIKP
IVLRDQLEVIPRIFHCTFPPEFAAALSRCKTDQEATEVGVEWCTAQCRDLVAHGVPSIHF
YTLMASDSIRRVAKEIY
>A0A840VF94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidocella aromatica|TrEMBL
MVPIPTSEAKPTEMMKMSEEMTEEMTWSCLEGLSMEATAKEAANLAASASRFAPGTIVAI
PFLPNESDDDRLQAAAAIRALHYNPMPHIAARRLPSRQALERLLAGWASMAHVDRLLVLA
GDCGKPEGPFEDALAVIKTGLLAEYGIRHVVISGYPEGHPKIPPQALVQAMRDKLRAVDE
LGLNAEIATQFCFSAEQVLVWLAQLRDSGITVPVRLGIPGPANMRTLLRYAAVCGVGASA
SVLARYGFSLTRLRSHAGPDQFVSDFLGGFTPSRHGEVFAHFYPFGGISGLFSWLDRQRF
IHAPAVKVKFS
>A0A6G1H0F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aulographum hederae CBS 113979|TrEMBL
MEKITDKIAALPEDGTYFSLEFFPPKTQMGSANLQARLERMSRALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNSSKAVVDDALEQAKALGVRNILALRGDPPRSEE
YNEDGLPTGGDKGEEEFVWAVDLVKYIRKTYGDYFCVGVAAYPEGHSDQSHPDDQNVEVD
LPYLVEKTKAGADFIMTQLFFDVEAYTRFEKRLREHESGVFKSIPIIPGLMPIQGYQTLR
RTTKLSHAKLPQQVLERLDPIKGDDEAVKNVGVDILSEIVEIIRDTASPVARRGFHFYTL
NLEKAVAQIIERTDLIPPADTPSSESDEAIEVVDMAATLKPGGRDRRRLSSVNSAPHNRI
VVDRSRDPSSSAVSRNANYEAPSDSAGIPGDRPTTRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAFGEIDGYGVSLHVSIPQALKLWGYPTTAADINDIFLRHVRGELDAIPWSE
EGLRPETNVIKDQLSKLIDKGWWTVASQPAVNGLPSSDPIVGWGPKNGFVFQKPFVELFL
PSSAWKKLKPRLETPENKNWITYFAGDARGAFEASDEESVNPVTWGCFQGKEIVTPTIIE
GVSFRAWIEEAFGIWGEWERVYPARSPTAKLLRGLREDVWLVNIIHHGYVEGDALWDVLL
EE
>A0A8J7HNM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amazonocrinis nigriterrae CENA67|TrEMBL
MDNNHSHTYLNCFRRAALAGEFLITAEVAPPKGGNPEHMLEMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQNGIEPICQVACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPDAKGVFDLEAVRLLQLIRKMNQGFDCNDKPLTDGALDLFPGAAVDPQCASWSGLQS
RFERKIEAGAQFFQSQLITDFERLEKFMDKIAAGYNKPVLAGIFLLKSAKNAQFINKCVP
GVNIPQHIIDRLAKAKNPLEEGMKIAAEQVQIARQLCHGVHMMAVKREDLIAPILNLAGV
APVDLVLAK
>A0A0Q4H071|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces sp. Leaf222|TrEMBL
MAPIAPEPAATPERTPLSFELFPPRTDAAAIALGRTIDRLADVDPAFISVTFGAGGTSRD
RSLTVLRYILENTEIEPMAHLTCVGSSHAEANELVRRFLDAGIRSFLALRGDPPAGSDPD
AALGDLATAAELVQLIHRVQQEREPFRQVAVAGHPEARRIRERERPTRVAVATFPTGHPR
SKDLSQDVDILLAKQAAGANLAITQLFWRADDYLAFADRARAAGVTMPILPGIMPTTTPA
RLARLTELTEVEPPAEFAIALEIEPDAAGQAELGIAYATRLAAEVLEGGAPGLHLYTYNR
HEAVLDVVGRLGIASPHQLANERNTER
>A0A377HIA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grimontia hollisae|TrEMBL
MGYSHASHLDALNQNLSDLNGDINVSFEFFPPSSEAMEQTLWASVQRLKTLKPKFVSVTY
GANSGERDRTHGIVKSIKQETGIEAAPHLTCIDASRDELRDIARDYWNSGIRHIVALRGD
LPEKSQKPDMYAADLVELLKGEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIIPGILPVSNFKQASKFANMTNVRIPAWMHKQYD
GLEDDPVTRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPTV
>A0A2Z6AM59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. YG1|TrEMBL
MPVIHPNWERPPVNMVDGYSLEMTAKDVESLREAAPAIARDTPVAVTFLPGEDFAARIAA
TKLVRSLGFEPMPHFSARRITSTTEFEDYLAAAVAEADVQRCFVIAGDPSEPEGPYFDSS
ALIASGAFERAGIRAIGIGGHPEGHPNMSPEQCWSVLTSKCSEIEARGMAPLIVTQFVFD
ADAVLAWLTELRARGISAPVRIGVPGPAGIKTLMRFAARCGVGASASVLAKYGISITKLI
GSAGPDKLVDRFERALGDEHGKVRLHFYPFGGLEKTVAWINDYARAH
>A0A417D242|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM42-11|TrEMBL
MKLSEAMRERMLLSFELFPPKTEKGMDNLPGTIDHLMKYKPAYISCTYGAGGGNVGANRE
VCQMIKKAGTTPVTHFTVIKNTKEGIKEQLDQYLAEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDSIREAGVTMPVDVGVMPILDMSATINMALSRNGCVMDRELCRLISRNWLFPN
PFAAKDADGKPFDMFYDDKIKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLCTLI
>A0A2T7M935|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CS147|TrEMBL
MDRATAASPSALAERVLAVEDGPKAVRALGIEHATEMCRRLIAEDAPGIHFMTMDFSQVT
TEIYRNLGLHAR
>A0A1G9J744|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. YR511|TrEMBL
MTAQTLYPAERGNLRLSFEYFPPKTDEMEAQLFQTADDLSVFGPAFITVTYGAGGSTKAR
SLTTVRRLIAESGFANTAAHLTCVGAPKAEVDAVIDEYLSFGVRHFVALRGDPQGGIGST
YQPHPEGYASSTDLVRAIRARGDDIEISVSSYPEKHPESPDVAADIDMLKRKVDAGATRA
LTQFFFDNNDFERYLERVRRAGVNIPIVPGILPINNLAQVQKFAGLCGATVPEAIVTRLV
HLEDQPVERFKEATHIAAEQIVDLARRGVRDFHIYSMNRTPLVTAVLDLVGFERVSVEAV
GAIDAPRMVAAGAAA
>I4LI62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis 284V|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIHSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKISEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A7T4A2A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei|TrEMBL
MSVSALRTLLKSARYEVLPTAGIVDRISDHVAPGRTITVTASTCMGLDATLSTAEALRAR
GYTAVPHIAARMVQGRTELEEIIDRLGRAGIDTIFVPAGDATPPAGGYASALDLLIDLTS
LAPPISQIGVAAYPESHPLIPDDVTVQAMWDKRDYATHIVSNLCFDPGIVSTWLARVRAR
GIEMPLILGIAGKVELAKLAKVATKIGVGESTRFLRKNTATFTRMAKPGGYNPRKFLDRL
SPVLADPYMGVSGLHIYTFNQVKDTEAWRRRQLELLGDPDPASVTS
>A0A1Q6K8X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. 42_12|TrEMBL
MLYQGNIRDYLSKQPLLFDGAMGTYLADKYIQFGGESCEKWNLRYPERIKQIHKEYIDAG
AVAIKTNTFAANAGDHFTAEEVGKVIAAGTQIAREAIEESAGEQILFGDIGPVLIGDEND
AAERYRLPVDCFLEQGVRHFLFETLDNIEGLDEITEYIKQKQPEAFIIVSFAVSPEGLTR
SGCYGRSLYQKMMNVSSIDALGFNCISGPKHLLDLMHKLSREKNTKYISIMPNAGYPAVL
DNRTYYEAHHYYYAKEMYQIAKQGASIIGGCCGTDPSFISEIAKTLQQSPLPGRKTYSAD
GSGRPVNSVVENRQTEQSIPVANDGQEVKNYAGKDNLRNTFAAKLACGEKVLVVELDPPV
TPEIDFFMEGAAKYQQAGVDAIDIADCPVAKARIDSSILACKVMRELGLTAIPHMTCRDR
NINATKALLLGLNVEGVNNVLTVTGDPVPAAERGLVKTMFSYNSAVLANHIRTLNEQIFQ
NNPFMISGALNVNAVNFDSQIIHAKRKISQGIDVLFTQPVLTERALNNLKRAREELDVKI
LGGIMPVVSYRNACFMNSEMAGIDVDPRIIEMYQDKDRAQGEELAEQISAQVAQEIAPYV
DGFYLITPFKRVELILRIIKQIRGLLDR
>A0A839FC63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium sp. P30BS-XVII|TrEMBL
MTIHELKAKPMTKIAASIEVAARQAIESQDLPGLFPEGTRVYITDMGTDGVDTLTAAAKR
IHDLGYKPVPHFASRRLGTRAALETRIRRAAEEAGVTDVLVIGGGLERQAGEFSSTMEVL
ETGFFDKYGINEMGVAGHPEGSPEFSEAVALEALRLKKNFGERTGARLRVVTQFGFDADR
FIRYAESLREHGVDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNALSLTALATSH
SPEGVVGPIEQHVINNPASAIKQIHIFPFGGLKKSSEWLVDRGSWNVASGHYASAAAN
>A0A6A7BB69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plenodomus tracheiphilus IPT5|TrEMBL
MERITDKINALPDDANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMDRSLVDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGQSPDQDSNKDFTWAVDLVRYIRKQYGDYFCIGVAAYPEGHSDESHPEHQSLEHDL
PSLVEKMKAGADFIMTQLFFDVEAYDRFEKTLREHESGAFKTIPIIPGLMPIQSYKILLR
TTKLSHANLPADMLARLDAVKTDDERVKQVGVKILDEMVEHIKARPNVGRRGFHFYTLNL
EKAVSHILEDTNLIPQTLPEDNESAVLEPTPAINLEPPPNGILSRRRHSSVNSGPRNRVI
VSHPSATRSSNHSYEALDSEAGIPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSNAQALKLWGHPVERDDISDLFRRHLEGELDALPWSEQALSD
ETLTIKTQLLALNKKGWWTVASQPSVNGVRSTDPVFGWGPRNGYVFQKPFVEFFIPSHAF
ANLKPRLDAHEQITYFAANAAGEFEASDEEAVNPVTWGTFAGKEIVTPTIIEAVSFRSWS
EEAFSIWKEWQRVYPSKSASARLVGGVRRDVWLVNVIWGDFVNGEGLWEFL
>A0A7J5WIC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrionaceae bacterium|TrEMBL
MESFLRINDLLSQGKRFISLEFFPPKEKDAWPSFFYEAGKLSILNPSFVSVTYGAGGSTQ
ANTLELVTRFSRDLGLNPMAHLTCVGASEDSLRSFLDGLQEAGVDNVLALRGDPPQGQPD
FKPENSAFQYASDLTGFIHKAYPDLCIGVAGYPETHPQAESAEKDLDYLKLKVDKGGSVI
ITQLFFNNDHYFRFVERCRARGIDKPIIPGVLPILNLASVKRILSLCGATIPAEYLARLE
AANDQGGAGAVRELGVEFAREQCRDLIARGAPGVHLYTLNKAQACLDIVNGLEL
>A0A667WB90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myripristis murdjan|TrEMBL
TVQDVRGDGNRVDGNCGGESSKESSRCSTPVLDADRSDRLRDKMLRRMESGDRWFSLEFF
PPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLETI
LHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKHIRSE
FDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRAETFLKFVRDCRK
IGIMCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIEQAVEM
CRLLLESGEVPGLHFYTLNREVATIEVLRQLGMWIEDPRRPLPWAMSAHPKRKVEDVRPI
FWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEEL
TSEDSVFEVFTCYITAQPNHSGHKVMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQ
PNINGKPSSDPLVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVQG
HNLTNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPS
RMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFEFLTSNFEIIAAETNTVVP
>A0A2R6JWY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QS_8_65_32|TrEMBL
MSLDTSQTTRTTDSVSTLLGEPRFELMPFDSFGEQLEYLPDGAAIAVTTSPQLGLDATVE
WTERGAEQGFAMVPHIAARYVRDEAHLEEIARRLTEAGVTDIFVPGGDREEPAGEFESAY
DLLVALNDIEYEFEEVGITGYPEGHDFLSDRTLADAMSAKEPYATYIVTQLCYDPEAVVE
WVREIREQGIDLPVEVGIPGVMKYQRLLEISRKVGVGDSVNFLRKTTGITGFVRQLIGSR
GKYTPDALVEELAPYATDPEYGIRGVHIYTFNQSSDTESWRYEELGK
>A0A7H0H766|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus defluvii|TrEMBL
MLHTDARLASVGRLLAEAGRPSFSFEFFPPRSEDEEPILWRAVESLAPLEPDFVSVTYGA
NGSRRDRTIAATRRIAEAAGGPLTVGHLTCVAQSRHELAEALAAYREAGVTNILAIRGDM
PGGGEWEAHPDGLRNATELVRFVKEEGDFCVGVAAFPHPHETSDDASLDAEILAAKVEAG
AEFAITQLFFEAEPYAALVERMAGLGCRVPIVAGIMPLTVISQIERFALLSGRDLPADLV
GRLRAAGSKEEVRRIGLESAVTLCRDLLALGAPGLQFFTQNRSKATREVLATLRGDVAVG
>A0A5C0SHH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crassaminicella thermophila|TrEMBL
MLIKDFYKNKKPIISFEIFPPKKDGPIETIYNTIDNLKDLKPDFISVTYGAGGSTTKKTV
EIASIIKNKYNIEALAHLTCVTSTKQEIENILNQLKDNNIENILALRGDFPNDPDFEFPD
PLHYEYAKDLIGHIHSNSNFSVGAAAYPEGHIECTNLDKDIYYLKEKVNSGVDFLITQLF
FDNEIFYKFKEKLDKENINIPISAGILPVINKNQINHILSLCGCHLPKKFIRIIEKYEYK
PEALKEAGIAYAIEQIVDLLSWGIDGIHIYTMNRPKTTRKIVESISTIRNVLTEE
>A0A0Q7BGW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root1257|TrEMBL
MSARSETARGTLKDTLARAGYEVIPLRRAEEDVLASVPRDVHLSVTASPGKGQDATLELA
ARLVGHGYSVAPHFSAHQVRSRSHLEELLAHCREANITEAFVIGGDRTDTPSEFADALAL
LRAMHDLGHGFTDIGIGGHPEGHPAVSDEVLMKAMQDKALLATHITTQIVFDPAVILAWA
RDLHARDVTLPIHVGVPGAVHRQKLLRVSSGLGIGESARFLTKQQGMLWRFFVPGGYRPD
KIMRGLAPHLGQPDNHLAGFHVFTFNDLASTEEWRTRSLKRLA
>A0A0F2QKP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium BRH_c29|TrEMBL
MSVNTPRVSFEFFPPKSDAMAKRLWETVERLEPMAPAFVSVTYGAGGSTRERTHETVKRI
AQETSLKPAGHLTCVSATKEEVLAVADQYWDAGVKHIVALRGDPPAGMGQAFEVHPGGFS
DSVDLIRGLRAHRPELGKCFEISVSCYPELHPESRGWDSEIAFLKAKQDAGADRAITQFF
FEPETYLNFLENARAGGVTMPIVPGIMLQANFRGLQRISGLCGATIPDWLADLYEGLDDD
EETRELVTANVAADLCRKLADQGVEDFHFYTLNRAGLALSTCRLLGLKPHPAKAA
>A0A5M8AU34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus cauae|TrEMBL
MQDRYYSFEFFPPKTPEGREKLRNTRAQLAPLGPKYISVTFGAGGTTQQGTLDAVLEIQR
DGIDAAPHLSCVGSTREGIREILRTYRDNGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFQIEVAAYPEYHPQARSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRAMGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDREAIRAFGLDV
VTALCERLLAGGVPGLHFYTLNAAGATKAIWQRLKL
>A0A1G9ET94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. YR527|TrEMBL
MDLQQRINDRAGEILLFAVTPPRVTTAPERVQQIAEITLERIRPLDVDGLILYDIDDESD
RNPEERPFPFVRTLDPADFLERNLAGLDVPAVVYRATGKYDEPTLRDWVKTQDPAKALSV
FVGASSGEKRVATSLRRAQEIRNQTNPELLLGAVAIPERHTAKGDEHLRLIAKQEAGCSY
FVTQVVYDVNAAKNLVSDYRYECETRGLAPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENELRHATDTLDASLEQAEATAIELMSFCRQLGVPFGINIESVSIRKVEIEASVRLAERL
RGKLAR
>A0A1F9U5V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_60_11|TrEMBL
MKITDILSRRKPIFSCEFFPPKTDEATAQLFETVRELKDLDPGYVSVTYGAGGSTRGKTL
EIVRRIKQELGIEAMAHLTCVGHSRSELKEVLDQIESAGIENVIALRGDPPKGETEFMPH
PDGFTHAAELAGFIRKNYKFCVAVAGYPEGHVEAPDRETDWKRLEDKVKAGGDLIITQLF
FDNRDFFAFEKRMREIGVKVPIIPGIMPITNLSQIIRFTRMCGAKIPEKALRELKELEDD
PEAVVDYGARLAAEQCKELLERGVPGIHFYTLNKSKSTRAIIEKLKNSA
>A0A1Q6KAQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. 42_12|TrEMBL
MKITQLLQEDKVTLSLEVFPPKKDTAVEQVSRSVREIAALQPDFMSVTYGAGGGTSAYTV
QIAKDIKAEYNVPSMAHLTCVSSTKETVKKQLECMQEAGIENVLALRGDIPADAEFPLPD
QFHYAVELVRYIKQIAPEMCIGGACYPEGHPEAVSKAQDIQHIKEKVDAGCEFLTTQMFF
DNSIFYNYMYRLREAGVLVPVIAGIMPITRKNQVERSIQLSGSCVPARFKSIVDWFGDDP
AKMKQAGIAYATDQIIDLIANGISHIHVYTMNDPEVAAGIMNNLSAILH
>A0A8G2BF59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobaculum litoreum DSM 18839|TrEMBL
MAPASARDVISLIDGFSVETTPASAAKVDCFADHLAPGTTVNVTFLPGSAIDDTIAVATR
LRREGFEPVPHIAARSIADSAMLDRTLGRLKDEAGVTQALVIAGGLDHPLGAFASSMDLL
ATGLFEAHGIAKIGVAGHPEGSPDIDETALKDALLWKNRFAAERGLEMYIETQFCFDAAA
ITAWDRRIRSWGNTLPIHLGVPGLATLKTLLKFAQMSGIGPSIRVLTRQARNLAKLMLVQ
APDRLLLDLAAYQAGDPDCGIEKLHFYPFGGLAKTAEWANAVASGDFIVDDRKAAILLGA
SDQAHAAS
>A0A8C3SCV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chelydra serpentina|TrEMBL
MVNEPHSASNGSASSRSDGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRYESGDKW
FSLEFFPPRTANGAVNLISRFDRMGMGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETVLHMTCCNQTKEEITGHLQKAKHLGLKNIMALRGDPIGEEWEEEVEGFNYAVDLV
KHIRCEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVSAGADFIITQLFFRSKTFLAF
MKDCQAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKEVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVSGLHFYTLNREVATTEILKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIHRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELMSEESVFEVFTCYISGEPNREGHKVTCLPWNDDPLAAETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSENITALLKVLKTKKYELRVN
YHIVNVRGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEEESPSRMIIQYVHDNYYLVNLVDNEFPLENCLWQVMEDTFGLLNCPTEP
>A0A7W7KVT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas euvesicatoria|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGAAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCQRLIAGGAPALHFYTLNLAKPTTQVLQLLGC
>A0A2L1WJS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fulva|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SQVQVPAAPHLSCVGDTKAELRALLAEYKQVGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEADLANFAHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEELLQGGAPSLHFYTLNQAEPSMAIWNNLQPSR
>A0A0U1NUG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neobacillus massiliamazoniensis|TrEMBL
MSFLEKLKNQILIADGAMGTLLYSYGTDCCFEELNLSHPEQIQHIHQAYIEAGADVIQTN
TYAANYLKLGRYGLEDSVKEINSAAVKNAKTVAGSNAYVLGTIGGNRGIKPTTITIEEIK
RSFREQLYCLLLEGVDGLLLETFYDLEELETVLTIARKETKLPIIAQVSLQETGILQNQL
PVNDALKRLEGLGADVIGLNCRLGPHHMLLTLEQIELPSHAYLSAYPNASLPSYNDGKFH
YEGDADYFRQSAQSFRHQGIRLLGGCCGTTPEHIRAFASELKNSAPISEKVVHFKPKKIV
SEARSPKRDCPPLQEIVKERPSVIVELDPPRKLDTRKFFEGAKELKKAGIDAITLADNSL
ATVRISNESLGYLLKSELAIRPLIHISCRDRNLIGLQSHLMGLHTLGMNDVLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNDGLSFSGKDLGQKTAFSIAAAFNPNVRSLEKAVK
RLEKKIQYGADYFISQPVFSEEKLLEIYENTKHLDAPIYIGLMPLTSSRNAEFLHNEVPG
IKITDSIRDQMAKWNDHPLQAVQEGLQITKSLIDAALDLFNGIYLITPFLRYELTRELAL
YARERANDTRRNSNVENTIY
>U2MKY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella salivae F0493|TrEMBL
MKVTDIIQQNKDQRRFSIEVLPPLKGNGTATLFATIDKFRELNPLYINITTHHSEFVYRE
LPNGQFTRNRIRRRPGTVAIAAAIQSRYQLPVIPHLICSGITAEDIEYELLDLQFLGIEN
LLLLRGDKAKDDRVFMPTPGGHSHTTELISQVNRFNKGLFNDGTSINHPGVPFEYGVAAY
PEKHEEAPNMKMDLEWLKEKQDMGASYAVTQLFYDNKKFFDFIQAAREIGITIPIIPGIK
PLARLSQLTVVPRTFRCDLPEELASEVLKCKTDEDAQHLGIEWGINQCRELYEVGFHNIH
FYTVSAADSVREIVRKLL
>A0A657B6M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleiphilus sp. HI0066|TrEMBL
METQKQFKRRFSFEFFPPKTEEGKAKLQVVRDELARRKPDFFSVTYGAGGSTQERTIDAV
LNFQDQGISTAPHLSCVGSSTQEIASLLDLYKERGVNRIVALRGDLPSGMGGSAGELKYA
NELVEFIREHSGNHFNIEVAAYPEFHPQAPSAEEDLINFKRKVDAGANSAITQYFYNVDS
YFYFIDRVEAMGVNIPVVPGIMPITNYTNLVRFSDMCGAEIPRWIRKQLEAYGDDKASIL
KFGEEVVTRMCEQLIDAGAPGIHFYSMNQAEPSLKIWDNLGLSDKEKIKF
>A0A231VQU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. Olga|TrEMBL
MTTVHPALSYELYPPRSHASCDSLLKTITELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLALRGDIPPENTRPLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETKRYSGLVDAARLAGVQIPIIPGIMPVTSLTRLTKLCELAGLEVPRELAHRLETASEP
REMHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>A0A1I5UKG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia sp. NFACC01|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRGILNTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGEAFHIEVAAYPEYHPQSRSARHDLENFARKVKAGADSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A5C1YSD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter sp. KACC 21233|TrEMBL
MFPAPQSCLLTERYGTTPQHEGAGPALSFEFVPSRTKAQEQRLWQCIRRLEPLSPRFVSV
TYGVGGTTRTSTQDTVMRLKRETTLAPAAHLTCVGAPREAVDEMARNYWQAGVRHIVALR
GDPPAGQAYTPHPGGYAYASDLVAGLRRIADFEISVAAYPETHPAAMSAAADLDNLKCKF
DAGATRAITQYFFDPILYVRFLDRCHAAGVTAPIVPGLMPVTNYTQVARFSAACGVDVPA
WLTRLFEGTQNNRELRRTLACVVMAEQVRILQGYGVNEFHISTLNAPEPAHTIAHILGVR
PICAGKTDF
>A0A1W9TQR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_19|TrEMBL
MKSGSNLEKVLTAGHFAFTGEVGPPRGANVEALREKARYLKDMVDMVNITDNQTAMVRMS
SWAAAIIAKEEGLEPNYQMVCRDRNRLAMQADLLGAYALGLRNLLCLSGDHQQFGDHPQA
KGVFDIDSIQLIGMVKKMRDEGKFLGGADIDVPPKFFIGAAANPFAEPFEWRVHRLAKKV
AAGADFIQTQCIYNMEKMRKWVQQANDMGLSEKVYILAGVTPMKSVGMAKYMKSKVPGMD
VPDDLIKRLQGVERKKVTEEGIKIACEQIEEFKEMKGVAGVHLMAIEWEHMVPQIAEQAK
VLPRPVV
>A0A7V9SI08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSKAPFREELSRRVLVCDGAMGTMLYAKGIFLNRSFDELNLTQPGVVTEVHQAYVRAGAD
IIETNTFGANRVKLAPFGLGDRVREINAQGARIARQAAREQAWVAGALGPLGIRIEPWGK
TGVDEAEDYFREQVEGLLEGGAELFVLETFHDVHEIAAAVRAVRSLTDLAIVAQVTTEED
GNTLDGAPPEAFVPQLEELGATVIGVNCSVGPAGMLETIERMARVAHVPLSAQPNAGRPR
EIEGRNIYLSSPEYMASYARRFINNGVRLVGGCCGTTPEHVRHIRNAVRALTPVAAGAPA
MASRARDAAQTSGSVQVAPIVRGEKSRLANALTRGVFTVMVELVPPRGHQAEALVEQARQ
LHIHGVDFVNIPDGPRASARMSALAASLVVQQAGVETILHYACRDRNLLGMQSDLLGAHS
MGVRNLLIITGDPPRIGDYPDATGVFDVDSIGLTNVVSRLNRGYDIGEQPIGQPTAFHIG
VAVNPGAPDLESEVRRFRYKVEAGAEFAVTQPLFGPAELVQFLARTEDVRIPILAGIAPL
ESLRHAEFMANEVPGVSVPAEVVERMRRAEEAGRAAAEGLEIARELVSAVRPLVQGIQIS
TVGGATESALEVMAAVTV
>A0A2L0T3T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. XWY-1|TrEMBL
MSLLRTALREQNFVCVMEFVPKPSAERFAAMEAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQVARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQATPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALEARIEYWQTQVQSLEQWAPA
WHASWQMPGLPAVTFHPPQAGWRLDESRVDASFKEKARYHLMHGMHALLFSRRNSLSKAF
GWAVRQPLWGTRVGAHVLHTLERSVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQAAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A7Y2U026|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MAAKPNISFEFFPPRTETQQRVLDATWRELAPLDPGYLSVTFGAGGSTLESTRETVLDLA
AQTAVPVAPHISCMAQSEEMLRTLLADYHEKGIDRLVVLRGDRPEGVGNTGPFDHANELV
AFIRREFGSAFHIEVACYPEFHPESESPASELLFFKQKVEAGADGAVTQYFYNVDSYFSF
VDDARRSGIDIPITPGVMPITNYRQLARFSQMCGAEIPQWIRRRLKGFGEDTEAIHAFGL
EVVTRLCERLLEGGAPGLHIYTLNRAQASKELWQRLNPV
>A0A839K0S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variimorphobacter saccharofermentans|TrEMBL
MKICELFQMKKVFSFEVFPPRRIDSVSIIYDTIEKLKGLNPDFISVTYSAGGSESNTDTF
KIASAIKNNYGIESVAHLPSINHTKGEVLKMLEDLRTAGIENILALRGDVNPSFSPKNDF
KFASDLISFIKEHGDFNIIAACYPEGHFESPSIIDDIRNLKRKVDAGANQLITQLFFDNN
YFYSFMERAAIAGINIPIEAGIMPVVNKKQIERIVALCRVNLPKKFLAIMNRYENNPEAL
RDAGIAYAVDQIIDLIAQGVDGIHLYTMNNPYIAHRIYEAINTLLVA
>A0A7Y1AL53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. WS 5019|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEVAAYPEMHPQARNFESDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSDSIRAFG
EQVISEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLSR
>A0A7C7SP31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTSTTNARLTQTPAPASVATPAIRLIRDIYAERRAQGRPALSFEFFPPKTPKGDVALFER
TLPALQTLQPDFYSVTYGAGGSTRDKTLAIVDRIQREHGATTMAHLTCISTSRLEIERYL
FEARAKGIRNILALRGDPPLATGSEQFERGFEYSYQLVEFIKQMGDFSIGTAGFPESHIA
CTEGRHVDWQRLKAKIDRGADFVLTQLFFDNDDYFTFRDHLVDTLGVSVPITPGILPILN
TGQIKRFTALCGATLPAALATKLERYGDDADAVADVGIEL
>A0A523EKC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTSLGRDAFSKRLSSAPLVCDGAMGTLLYGKGVMVHRCFDELNLSNRELVLSVHRDYLAV
GVDVLETNTYGANRFKLEPHGFKDRVREINEAGAAVARGAIGAMDGPVLVAGSIGPLGKP
IAPIGTISEEEALASFGEQCEGLVAGAVDFVILETFSDLRELSLGIRALREVAPDLPIVA
QMTYGDDGSTPLGAKPEHVARKLSALDIDAIGANCSVGPELMLRVVERLATATNLPISVL
PNAGLPELVEGRVIYLSSPEYMAHYAKRFLKAGAAMLGGCCGTTPDHIGAMVGVVRALGP
ARTQIEVATPAQDYIEREPVPREKKSRLARALGRKFVVSVEMDPPKGADPGLFLEKAQWL
KENEVDYINVGDGPRASARMSALSFAVLLEQRVGLETILHYQCRDRNLIGIQSDLLGAQS
LGLRNILAVTGDPPKLGDYPYATAVFDVDSVGLTKILGRLNRGLDLSGNPLGLALPFHIG
VGVNPGATDFDEEIQRFQDKVEAGAEYCLTQPVYEARYLERFLEAIESYRIPVLVGILPL
VSSRNAEFLHNEVPGMAVPQEIRDRLRSALTKEAAQQVGVDVARDALRAARDLADGAYVL
PPFNRFELAVQVIADII
>A0A8I0J794|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. ENS10|TrEMBL
MTAQTLYPAERGNLRLSFEYFPPKTDEMEVQLFQTAGDLSIFGPAFVTVTYGAGGSTKAR
SLTTVRRMVEEKGFANTAAHLTCVGAPKAEVDAVIDEYIDYGVRHFVALRGDPQGGIGSA
YQPHPDGYASSTDLVRAIRARGDDIEISVSSYPEKHPESPDVAADIDMLKRKVDAGANRA
LTQFFFDNNDFERYLERVRRAGINIPIVPGILPINNLAQVQKFAGLCGASVPEAIVTRLV
HLEDQPVERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLVTAVLDLVGFEQVALEAN
NALDEAPRTRAAGAAA
>A0A7V9LUQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
TRVYITFLANTQFEDTLSLAARAVREGMRPVPHLAVRAIRDRAALTGMIAALAGIGVTEV
LVVAGSVSKPAGEYEETMQVLRSGVLPEHGIIRIGVAGHPEGTPDIQAADLAAALDAKNA
LAAEQGIDMYLITQFCFAPEPIITWEREIRAAGNRLPIVIGLPGLTSPAKLLRFGLSCGI
GPSLKVLRKQSGGVLKLATSSVYHPDQTMLGLVRARTADPASLIRGVHFFPFGSLLRTAE
WATQVSAGQFVVERNDTLRVTA
>A0A5J4XQB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trebouxia sp. A1-2|TrEMBL
MAHTRVSRLPVSSAKFTASAQPVKLQGSIHELFSHRPAVTLERSVGKTLGADIELWESGH
FGAGIIPDLPVVSSWKELGAKLLGRSITVVQIDAGAEVIVTQPPLLWDKFEAWINSVQQQ
RLLDKTRLIVGCPMVSSAANMKFWLYLCRASHLPEAASAVQPFTDAAAESKQCLAAYCQK
YNADLIHRVLQFPDVAGIHVMPLTKQARQQTMPLMQCLS
>A0A2V9VLQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MASDFLSRLSKSPILCDGAMGTLLYANGIFINRSYDELNLSQPEMIHSVHQSYLQAGAEI
IETNTFGANSFRLGRYSLADKVHEVNRAGARLAREAAKSFDVWVAGSVGPLGIRIEPLGK
TSFEEARAAFREQIAALAEGGVDLLILETFGYVEELHQAMLAARDVNPKLPVVASVTVDE
ESNCLDGSDPETFAAKLADWGADVIGCNCSIGPVAMLDAIERVRAVTTMPLAAQPNAGMP
RSVEGRNIYLCSPEYMASYAKKFVAAGVRLVGGCCGTTPEHIRMMKSALRVGEARAARVQ
TAKPQPSPAAGPTEPIELRSNLGRKLIAGEFVTMVEIVPPKGTDIRKEVEGARFLKSVGV
DGINIPDSPRASARISNQALSLIVQREVGIEAILHYTCRDRNVLGIQSDLLGAAAMGIRN
LICITGDPPKMGNYPDATAVFDVDAIGLVNIVHNLNRGLDIGGNAIGAGTGFVIGVGANP
GLPNIDEEIRRFEYKVEAGAEYAVTQPVFDLALLENFLRRIEHCRIPVIAGIWPLVSVRN
AEFMKNELRVSVPDSIVERMAKAPTPEAARQEGVAIAREMLIAVRDLVQGAQISAPNGKY
AAAVDVLEALGAGSRERQSSVFSPQSSA
>A0A832GKL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldimicrobium thiodismutans|TrEMBL
MVEKSYLQSVLEEGKFAVTAEIGPPKNADPEVIKKKARLLRGYVDAVNITDCQTAIVRVS
SLASAVLVMSEGLEPVMQMTCRDRNRIGIQADLLGASALGIRNLLCLTGDHPKFGNHPQA
KPVFDLDSIQLLNLVKRLKEGRFDNGEEIKGVRPYFFTGAAENPFAEPYDFRPYRLAKKV
KAGAQFIQTQIIYNVDRFRAFMERCRELGLLDQVYILAGITPPKSLGMAKYMKYNVPGLE
VPDEIIKRLEGAKDKREEGIQIAVDIIEQVREIPGVRGVHIMAIEWEEAVPEIVKRAGLD
DRVRAPELKPPFVVEKVVEKVIEKPVEVVVEKVVEKIVEKPVEVIVEKIIEKEIPVEVEM
AGGRMSLSSFIEILSDLKASLKNIKSGMESVEEAIAKLEEEFLGKREVKPVIKEIVKKPA
EEITEPLPKEEVKVEIKPEAKVELKEEVKEEVRAEVKEEKPEVKAEVGPEIKPEAVEKVE
VKEEAKPEVRVEPEERIEAKPEVKEEVKPEVKPEEVEKPAPEERVSEIKILGFKGAYRPL
SERAGKIAQDLYMEKATGEIKEVVIGKGEKAIRCGGVSAINFHLFEGTMKNGVKIAMEIL
DVKPEDWPESLAKYFSDVYHDPALWAKKCVEEYGAEALCLYLVGTDPNFLDLPVDHAKKV
AEKVVKAVDVPLIVWGSGNAEKDVEVLRDVADIVGERGACIGPVVEANHRTLAAVAMGYN
IPVIASSPIDVNLAKQLNILLENMGVALDKILMDPSIGALGYGLEYTYSVMERIRLAALY
AQDTKLQVPFICSIGKEVWKTKEAGLPTDELMGDAEARGILMEALTGVTLALAGGDLLIM
RHPKAIELCKVLFNGLSLS
>A0A7V8WHA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPRQSFLDAIDQRVLVCDGAMGTMLYGRGIFLNRCFDELNLTQPDLVAEVHQAYVRAGAD
IIETNTFGANRMKLGTFGLAERAHAINLQGARIARHAAREQLYVAGAIGPLGVRIEPWGK
TGVDEAEQYFREQAQALLEGGVDLFILETFRDVNEVSAAISAVRGLCDLPIVAQVTTEED
GNTLDGAAPESFVPGLEYLGATIVGVNCSVGPAAMLETIERMAQVATVKLSAQPNAGRPR
EIEGRNIYLCSPEYMASYARRFINNGVRLVGGCCGTTPEHIRHIKMAARALAPAERPREK
VSVPRPATPPVEAVPRAQKSRMAAALGRSEFVTSVELVPPRGFNADGLIDQARELRANGV
DLVNIPDGPRASARMSALSASVIVHQQTGIEPILHYACRDRNLLGMQSDLLGAHSMGIRN
VLLITGDPPSAGDYPDATAVFDVDSIGLTNVVSRLNHGLDVGGQPIGAPTAFHIGVAANP
GAPNVDDEIRRFEFKVKAGAEFAVTQPVFDVGALSQFLARIGHIRIPVLAAITPLESLRH
TEFLANEVPGIRVPELIVERMRRADGEGRAAEEGLSIACEIAVEVRPLVEGVLISPATGA
LRSGFGVMKALTECSRP
>A0A2E7AQ17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MHIINKINQRIREKKPFYSFEYFPPATEAGLHNLYARIEQMVALEPIFVDITWGAGGSTN
EKTLGIAENLQKFFGLDVMMHLTCTNMPIEQLDEVLEKARAAGIRNILALRGDPARDSSV
WERVEGGFTYAYELVSHIRERFGDEFCIAVAGYPEGHLEAEDKDTCTGHLKHKVDCGADF
IITQLFFDINEYAGFLERCDKQGITCPIVPGLFPIQTFDRFKKFVQFTGANVPTEVWDCL
EPIRQDDAAVRSYGVELCIEMCEKLSGLGVPGYHFYTLNLQSSVMLILEGLGAADGLAVD
RQLPWRPSTFPTRREEDVRPIFWSNRPKSYLARTMDWDEFPNGRWGDRRSPAFGTLNDYY
LLRRGIGLEEKXQKLLEAYGNPKSLEDVYDVFARFCAGELDSFPWVDGEIQAETKRISTE
LVALNQAGFLTINSQPQVSGAPSNDSEVGWGGANGXVYQKAYLELFXSDDKLQIFLDHVD
RFPTLTYQAVNVEGTTHSNLRPDAVSAVTWGIFPGEEVIQPTVVDAKTFHVWKDEAFEIW
REEWAALYEEESTPRRLIEEIHDSYWLLNLVENDYINGDIFAIFRDLGVLE
>A0A2V8AKC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MLKALKEAIEERVLVCDGAMGTMLYAKGVFINKSFDALNVTQPDLVAEVHAEYVRAGADI
IETNTFGANRIKLGSFGLADRLHAINEQGARIARHAADDRAYVAGAIGPLGIRIEPWGKT
GVDEARDYFREQAQALADGGVDLFILETFRDLNEMGAAIDAVRAVSDLPIVAQMTTEEDG
NTLDGTPPEKFAPELERRGATLIGVNCAVGPAPMLDTIERMAAVTKLKLTAQPNAGKPRD
VEGRNIYLCSPEYMASYARRFILHNVRLVGGCCGTTPEHIRQIKMAVRALAPAVVRASVE
TPRAGAAPSPPLSRVEGPPVPRDQKSRLARSIANRRFVIGVELLPPRGYQTDQVVERARR
LKIGGVDVISIPDGQRGGARMSALSLAVLVEQQAGVETLLHYACRDRNLLGIQSDLLGAH
AMGVRNLMLVTGDPGRVGDYPDATAVFDVDSIGLTNVVVRLNRGCDVGGQPIGAPTAFHI
GVSINPAATNLDQELRRFEYKVDAGAEFIVTRPVFDVRAFEQLLRRLEPAGLPVIAGLFP
FESARNAEFMANEVPGVRVPDALLERMRKSDGRSGGAAEGVAIAREIASELRSAVQGFQV
STQSGDVESALSVLDGLR
>A0A7W0KL72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MLSDDSRSRLRRRFSEQIVVCDGAMGTMLHSTGMPLDRSLCELNVTQPRLVRDLHAAYLS
AGADIIQTNTFDANRLRLSRVGLEDSVVELNIAGARLAREAARDSDRTVLVAGSVGPANS
ATALSRIPPGMRAEVLREQIAGLVDWVDLLILETFGDLDSLVQAVEVALEETDLPIIAQM
TFGDDGRTLRGEGPAAVVAVLDRMDVAAIGANCTVGPAALQDVIAELAASSRTPISVQPN
AGTPQRLGRQVRYVHNTAYFAAAAAEFVGNGASIVGGCCGTTPAHTRAIAKAVSGLVPAL
RVQRLTSTYPDPVATGSTAAGTAPDRPTWPQDGGFVIIAGLGAPQGPDVDGFVEQARELR
AAGAQVLAITEPAPPATRVGPVAAAVVLHERVDAEVLLPAETADRTLPALQADLLGAHAL
GLRMVVCRTGSPRVAGDYPDAALPWDVDSVRLIAALRGLNEGQDWRGVATRERTQFVIGA
SISTAAADLNREIERAESKAAAGAHFLITDAIYDADEAILLLAALHARGIDIPVIASIAP
FESFRALERLRNEVPRMSVPPAGLRTPRRPGAALSDVVEASVELIEKLRGLISGVLVQVP
RASQQPAVDLLGRLSGFGVRR
>A0A2V3J8K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanophagales archaeon|TrEMBL
MKRRSDEIYSDLMRELEEGRYVFTGELEPEKAGDVNEPIEMARELLDLVVACNVTDNPQS
FAYVSSLAASYQIQKETGMECVYQLRCADRNRMALLSDVLGAGVLGIKNILALAGDHVSL
GDTPDAKPVFDLDSTTLIKLIRTVVSEGKDLAGNEIHNPPKLHVGGAAAPGAAHLKAEVA
KVKRKIKAGVEYLQTQVVYFTDVLDRFFKELGPVDVPILVGIFPARTFGQADFFDKFVAG
VDVPPDYLENMRATKQIKDKEKRKEEVDRVNVEFFTGFLEHLKGTPAAGCHMMAVGYPRV
IPALKKIME
>A0A8I0MBU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. ENS10|TrEMBL
MVAALAAANGSALLENPGEAMTNPAEACTDTRVHPGDGANTTISIELAPEQVRNFAPQAD
TLPLGSRVFLTHLAGKPEALQVEAAARITELGYVAVPHLAARNFKTERDYVNLVEAHSRN
GIDEVLFLGGNPALFPGPLGESAELLAHPVLSDSSIRTAFVAGYPEGHPNIPEVRLKDAL
KRKLEICARRSLEPRVVSQFAFDGAMIGAWAKRLHDDFPEVPVHVGLAGVTSLTKLIRFA
AMCGVGPSIAALRRSASGLLNIVADRNPADVIDAVSSAYPDPATPLHLHFFPFGGWEKTL
TWLGDYREARQLRAGVR
>A0A7W1DNW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
GSPREVEGRNIYLCSPEYMASYARRFINNGVRLVGGCCGTTPDHIRQIKSAVRALTPATP
ARDKTPAAARPAPEIRVVPRPEKSRMANELARGGFVVAVELLPPRGYDAHGLIEQARQLR
IHGVDLVNIPDGPRSGARMSALSASVLVQQQAGTETILHYACRDRNLLGMQSDLLGAHSM
GIRNVLLVTGDPPAAGDYPDATAVFDVDSIGLTNVVTRLNRGLDIGGQPIGMPTAFHIGV
AVNPCSLDLDLEFRRFKYKVEAGAEFAITQPVFDVAPLVAFIERSAAGIPVLAAITPLES
LRHAEFMANEVPGVCVPAAIVERMREAERDGRAAQEGLAIASELAAGVRPYVQGIQISTA
VGAVESALGVMKALAA
>A0A0Q8VMI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root79|TrEMBL
MVTGAGRSLGELIREGGRSYSFEFFPPKDEAGEAQLWEAIRALEPYRPTFVSVTYGAGGS
TRDKTVAITGRIARETSLIPMAHLTCVGHTRDELESILDAYDAEGVAHVLALRGDPQEGP
RADWTPTDGGLNYAVELVELARARGSFRVGVAAFPEGHPSAESLDHDADVLVAKARAGAE
FAVTQMFFRASDYFGLVERVRARGVDMPILPGIMPILNLSAIRRQGELIGTSVPEEIVER
ISAHDGDAAAVRAEGIRIAAELCDELLAGGAPGLHFYTLNRSKATLEIFEALQITV
>R1GD30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis vancoresmycina DSM 44592|TrEMBL
MTSVIERLRGDGPKFSIEFFPPRDAADEAVLWKAIRELEPYDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYASVGVRNILALRGDPPGDVYGDWI
PHPEGLTYAEELVQLVRSLGDFCVGVSASTYGHPRSADLETDTKYLVRKLRAGADFAIAQ
LFHDAEDFLRLRDRVAATGCDVPVLPGVMPLTTMRTLQTTIKLSGAPAPRKLLDRLEPLA
DDPKAFRAAGIDVITELCEKLIAEGVPNLHFYTFNRSKATREVIARLGLVPARA
>A0A1C5P8U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Blautia sp|TrEMBL
MKITELFERGEFVVSAEVGPPKGIHIEHLLEEAKTYLSGITAVNVTDNQSSVMRLGSLAV
CKALKDEGLTPIFQMTCRDRNRIALQSDLLSAAMLGIENLLLLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVRKLEEGEDLGGNKLVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVRAGA
DYFQTQAVYEPEKFIKFMEKAKQFGKPVQLGIVIPKSAGMAKFMNDNVAGIHVPQEMLDE
LKKDKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAGL
>A0A3C1HJU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp|TrEMBL
MSKRISFEFFPPKTEQGREKLLNTQQKLLAKKPEFFSCTFGAGGSTRDYTRQMVGLLREQ
HADTAPHLSCIGQSRDEIMELVNGYKESGVRRIVALRGDLPSGMGYAQSEVKYADDLVAL
IREETGDHFHLEVAAYPENHPQSRSFDDDIAHFQRKIRAGADSGITQYFYNADAYGYYMD
ELRRRGCDAPVYPGVMPILNVANLFRFSDNCGADIPRWLRSRLDDIRDDEQAVKAFGEEV
VTRLCERLLAMGAPGLHFYTMNQSGPILRVLDNLGL
>A0A3N5YW03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSLGATGSPETNKSGLLAGSNLEKVLRAGHFAVTAELGPPQSADHAAIRNKARHLRDCSD
AVNLTDNQTAIVRMSSIASGAILVQEGLEPVIQMVCRDRNRLAMQSDLMGAYALGIRNVL
CLTGDHQSFGNHPTAKNVFDLDSIQLVRMVSGMRDQRVFQCGEAMKGPEPRFFVGAGASP
FAAPVPFRPYRLAKKVRAGANFIQTQLVYDIEAFEIFMETVRKLGVHEQAYILVGVGPLK
SPGMARYMKESVPGILVPDQLIERMNRAGAQWAGRKPEELSKEEKKTRSEAWKAEGIKIC
IELIQKVRAVEGVAGAHIMAIEWEEAVRPIVDGAGLLPRPNLS
>A0A0S8C2D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium SG8_41|TrEMBL
MNAPALNSSTGQLEAALRAGHFVMTAETSPLDVATAAPILARAGCLKGLADAVNVCDGPS
ARAHISALAESAILAQNGIEPVLQFTVRDRNRLALQGDLLGAAALGIPSILCLHGDDIKK
GDQPDAKPVHDIDSRELMNTARRMRDEGVLPSGRALESRPRLLIGAADTPVDPKPGWKPD
GLRAKIDAGAEFVQTQFCFDLGLLRRYLGALADDGILERVYLIVGIGPIPSAKSARWMNA
NLWGVSVPEPMIQRLERAQRPEAEGRRICVELLQELAEIKGVAGAHMMGPKQEQAIADAI
VESRLLARRGRA
>A0A426FMH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lautropia dentalis|TrEMBL
MTQHTASRTPQLSFEFFPAATDAGMQKLLDAHQALRTLDPAYFSVTFGAGGSTQARTTEI
VTALTQAGSQVAPHLTCVGATRESIRSLLDSYRDQGIRRLVALRGDLPSGMVGLGDFRHA
IDLIRFIRDAYGDWFSLEVAAYPEMHPQAESPDADLARFAEKAAAGAHSAITQYFYNPNA
YFDFVERAERAGVTIPIVPGIMPILNYTQLARFSDACGAEIPRWIRLRLASFHDDVDSLR
AFGHDVVVDLCQQLLDGGAPGIHFYTMNQAGPSTAIWQALGR
>A0A4V2R4M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum steppense|TrEMBL
MSAPRVSFEFFPPKSLEASFQLWETVQALAPLKPQFVSVTYGAGGTTRKLTHEAVETIHN
RYGVNVAAHLTCVDATRAETLEIADAYARAGVTEIVALRGDPPQGQGVFAPHPEGFANSC
DLIEALAARAAFTIRVGAYPEPHPESRGAGHDVQWLKRKFEAGADSAITQFFFEAETFFR
FREECDAAGIDGTKIIPGILPIEKWAGVRRFAERCGTKIPAWVDEAFDKAIRDGREDLLG
KALATELCTELMEGGVQDFHFYTLNKPHLTRDICHALGVLPAGHLEKVA
>K0ET95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia brasiliensis ATCC 700358|TrEMBL
MPFSVEFNPPRDAPAEARLWRAVRQFERMHPAFVSMTYGAGGSTRDRTVRVTGALAQETT
LLPVAHLTAVEHSVAELRSLVGSYADSGIRNILVLRGDPPGDPLGAWQRHPEGVEYAEEL
VRIVRDLGDFHVGVASFPQGHHRSPDLDSDTAFLTAKLRAGAEYSITQMFFDVEHYLRLR
DRVLKFDPIEGAKPIIPELMPITSLRTVARAEELCGRTLPPAVLARLHHAAGDAPDGNPA
AVREAGIEIATEMAQRLIDEGAPCLHFITLNFAKATTEVLTNLGYGVTAAPISA
>J9DT08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wuchereria bancrofti|TrEMBL
MRLQDENPVLYKYRALDLIRWIKEEYNDYFTIACSGYPAGHPEAPSYRADLLYLKAKVDA
GADFIISQIIFDGEVFQNFLRDCREIGITVPIIPGILPIQSYESIRRIAELSQLVIPDSI
LTSLEPIKNDDDAVRNFGIWHAVTLCRTLFSNGSATSIHLFTLNREASSR
>A0A091BQM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus equinus JB1|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPEKVLAIHKAYIEAGADVIQT
NTYAAKRHRLDGYGYGDKIKEINQAGVKIARQAAGEDTFVLGTVGALRGLKQCELTLDEI
IKETLEQVGYLLETEEIDGLLFETYYDEEEIIEVLKAVRPLTDLPIITNISIHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVSRKFVTP
MVEEAELIKAVKQSETIVDKVKRKVTIIAELDPPKTLDIRKFTKGVKALDEAGVAAITLA
DNSLAKTRICNVSIASLLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIKQLNKGIGYSGASIKKETTFTAAAAFNPNVKNLS
RCGRLIDRKIAAGADCFITQPIFNSEIIENLAELTRDYETPFFVGIMPITSYNNAIFLHN
EVPGIQLSDDFLAKLEAVKDDKEKCQQLALEESKQLIDHALKFFNGIYLITPFMRYDLTV
DLVEYIHQKVEQSHQIIP
>A0A6N1VBJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oricola thermophila|TrEMBL
MRNYVRSVTGNRGSGQEIRVSFEFFPPKTPHMEATLSETIRRLNPLGPDFVSVTYGAGGS
TRDTTRKTLEMVLATGNTPAAAHITCVDATREEVDAVVREFAALGIRRFVALRGDPAGGV
GTRYQPHPNGYQNAAHLVAGLKAFGDFDISVAAYPERHPESPDFATDIDMLKRKVDNGAT
RAITQFFFDNDIYERYVERVRRAGIYIPIVPGIAPIHNFSALRNFASKCGATVPDWLADR
FEGLENDPQTHALVASAVAAEQVFDLVDRGVSDFHFYTMNRPDLVFAICRLIGIRADKPV
SELNAA
>A0A0H3ABG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio vulgaris subsp. vulgaris (strain DP4)|TrEMBL
MKIAEAIERQSRPFYSLEFFPPKEREQWPAFFATVERLKAMDPVFASVTYGAGGGTQDNT
LDITAHLKNALGLEPMAHLTCVGATRERIAGFLARLREQGVENVLALRGDPPRGQQVDWE
TAEFRYASDLVRFVRNEFPEFGIGVAGYPAAHPESVSFSQDIAHTCQKIHAGADFVVTQL
FFDVREYFAFIERLKECGVEKPVLPGILPIQSLESIKRILALCGANIPGKLYLELEEADA
RGGAEAVREAGIAFAVRQIRSLIDGGAPGIHLYTLNKADMCLQIRDAVGAL
>A0A1Y3YQ71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides clarus|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESAFTPEGNGYHHAIELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTKEVLKCKNDTEAQQVGIEWCIQQCRELMEHRIPSIHF
YSIGAVDSIREVAKQIY
>A0A0Q8Y8S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrabacter sp. Root85|TrEMBL
MAHGTASSMARAERFTRSIPAMIEADTPTYSFEFFPPKDDASEAQLWDAIRRLEKVSPSF
VSITYGAGGGTRDRTVRLTQRVLEATSLTPMAHLTCVGHSVAELRGIVGSYAAAGVRNIL
ALRGDPQGGLGQPWVAHPEGLDHADELVALVRGLGDFTVGVAAFPDGHPESGDISEDAET
LIRKERAGAEFAITQMVFDVDHYLRLRDELARRGSRLPVVPAIMPITNARQVVRMAQLAG
QPMPTAVTDRLERHGDDAAGVRAEGMAIATESSRRLLDEGAPGIHFITMNRSSATLEVFG
NL
>A0A0T9UM55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia aldovae|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDAFPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMTSIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A200HHC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium sp. PE09-221|TrEMBL
MMTATTLPMLDDCPKTMRVGPCGGVFADGGCEIRPQEACVFLDERRSDDFGRAEQALLEA
TGERPERPQSSSRLREVLERGDFATIAEVNGADSADAVGFVAAAQKVAEAVDIVSITDNS
GANIHMGNIAATAHLRAAGLDVMPTFACRDRNRMALQADLLGAASLGARNALIVTGNHVA
VGDSPDARPVFDVDSPRLLAIADRLRTEGLLDNGRAVETAPDLYLGSVAHPFAPPYAERP
QHVARKVRAGADFIISQHIFDLPRWRSFVAEVNARRGAERPFHLLGGIAIMPDETIARRV
NAGLRGFSIPEDLLLRLRQARDPQDEGLEIAAELLRELIDTEGVDGALIAPVTGRQNALT
ASIEQRELIAELRHRAGIPVAAPQQAGSR
>A0A7N9CEX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macaca fascicularis|TrEMBL
MDHRKARVLPAGHYCPSLGIWASKAGSVRFSVPPSISRNLAMVNEARGNDSLNPCLEGSA
SSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDALELLNRPTQNERETEAP
>A0A7C7XML4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micavibrio sp|TrEMBL
MGLKNVCAAKPTISFEYFPPKSEKGLSNLLTEVGELVKLRPRFMTVTYGAGGSTREGTIK
TVKEIWNAHKVPTGSHLTYLNTTKEELDRITDDLWDAGIRHIVALRGDMPADLSWPLDPD
ADYYQFTSDFVEGIRERHPFEISVGAYPEKHPDSPDLSADILALKKKFEAGADRGITQFF
FDNDVYYEFLDDAAKHGLNKPIVPGLLPIADYEKMLSFAETCQATVPHWLREKFEKFAGS
DEDKAKLATDILAAQVDDLAANGVQHIHFYTLNKAGITEKACKKCKLG
>A0A8F7ZLR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes ammonioxydans|TrEMBL
MSKKQTLSLEFFPPRDSAAQEKLVRTAKTLMGLNPAYVSMTFGAGGSTRAGTVDAVALLQ
NLGLDVAPHLSCIGTAPAQLGEMLDTYRDQGIRRIVALRGDLPSGMGGDTGELRYASDLV
SFIREHYGEHFHIEVAAYPEMHPQATSLEEDLGHFVNKVKAGAHGAITQYFFNPDAYFSF
VERAQAQGVTIPITPGIMPITNSSQLLRFSTMCGAEVPRWIRLRLADFGDDRASIRAFGI
DVVTRLCQDLLDGGAPGIHMYTLNGADASMAILPNLTWR
>A0A8E4B5H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii|TrEMBL
MALKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTRAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESHDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRPGRETKSAGA
AA
>A0A6A7TVK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHAHATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQMGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDDDAKQLGIEWTTAQVQDLFEHGYNNVH
FFTVSAVDSVKQIAKILF
>A0A3A5I6H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis|TrEMBL
MGLLEDLQKQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIVQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTS
LSEALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTRAKEFIS
VQHERTEPGLNELAAEKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQKLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIYLH
>A0A8B5NRP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis|TrEMBL
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDDIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVSGLAPITEKEVKTRAKEFIS
VQHERTEPGLNEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMAHAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>A0A1H4I0D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. 276b|TrEMBL
MKADLRSVMQERVLIGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
HETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGANGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLEEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGVPMSVYPNAGAADYVD
GQFRYGASPEYFGQTAVQFADLGARIIGGCCGTTPDHIAAIAQALVEYTPVPILEPDPSE
SKPRIILHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVSFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATKHFKGIYLMTPFMFY
SMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A2N7G6I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 10N.261.55.A7|TrEMBL
MGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLIAAPHLTCIDASREELIQIADDYWNNGIQSIVALRGD
IPPGGGAPDMYATELVKLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIEAEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQG
>D0XAR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio harveyi (strain 1DA3)|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDASRDELINIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A327K4L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoplanes piscinae|TrEMBL
MRVSFEFFPPKSDEMERTLWDSIERLAPLRPHFVSVTYGAGGSTRERTHATVKRILDATP
LTPAAHLTCVAATRDEVDAVVRAYVAAGVRHIVALRGDPVGGLGTAYAPHPGGYLNGADL
VGGIKRLAAAEHADIEVSVSAYPERHPESPSDAVDLDMLAAKVDAGASRAITQFFFDNDL
YFRYLDRVRARGIGIPIVPGILPVQNFKQTRAFAERAGASIPSWLADRFAGLDDDPATRK
LIAAAVAAEQVFDLVDRGVTEFHFYTMNRADLVYAVCHLLGLRPVVSPAAAGTAVRAAAV
A
>A0A069KBD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NTK 937|TrEMBL
MHPLDTASASVGTPLLEDFSLEMTGKDVPELEAAAGALPRGTRVNVTFLGNEDPRTRLDA
ARAVKRLGLLPVPHISARRLTSRTDFEQFLAGLRDDGTATHVFTVGGDPALPLGPYDSAL
ALIDSGLLQEHGVRHVGIAGYPEGHPALTDDTLRAALRDKAASLTAHGLTGHVTTQFGFD
PDPVLSWLEDVRDQGITLPVRIGVPGPAGVRRLLSYATRFGVGTSASIARKYGLSLTNLM
GTTGPDVFLRTLAERYDPARHGEVKIHFYTFGGLRATAEWIARFRQDNLV
>A0A2N6SWI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium xerosis|TrEMBL
MSDFPPPAVGRQVPVRHALTLPSPGPVPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFA
SVTYGAGGSSRDRTLRIAERVSREPLTTLVHLTLVGHTVPELREILRAYLDRGLTNLLVL
RGDPPGDPLGDWTPMEDGLSYASELIEFIRSEEEFADFEIGIASFPEGHFRAPDLESDTR
YTLAKLRAGAEYSITQMFFDVDHYLRLRDRLAAEDPEHGAKPIIPGLMPVTSMRSVRRQL
ELSGSVLPAALDERLTRAAAGDEEANRDEIRKVGIEVTTEMAERLISEGVPGIHFMTLNF
ARATQEVLNNLGMAPAWGTGQDMLRGGF
>A0A496P933|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp|TrEMBL
MSETIQQKRPTLSYEIFPPNTQVGDEKIITVLDELKSLKPEFISVTCSNKQRNIEETTIK
LSNYVQNTLHIPTKAHLPAIYLSKEQVRSVIDQLDQLGIHKLLALRGDILEDLPPVGDFK
YASELVHFVKDYAPHFQISGACYPEVHPDSPNQLQDIKFLKEKVDAGCELLVTQFFLDNN
VFYDFQEKCALAGIDVPILAGVMPIINRNQALRLLTSNATAIPRKFKAILDKYEHDPIAL
RDAGLAYALNQIVDLVTEGVSGIHLYTMNQSNTALYIENAARSLFSSPIYENQ
>A0A1Q7I511|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium 13_1_40CM_4_68_4|TrEMBL
MRVSETFKLGRPVFSFEFFPPKSDQAARDLFKTIDQLQTLRPDFVTVTYGAGGSTRERTI
ELVTELKHRLRIEVAAHLTCVGHNADEIARICERLRSNGIENLMALRGDPPKGEATFTQP
EGGFGHATELIRFVRGRFDFCIGAAAYPEKHLESPSLDDDVRWTREKVGAGASFLTTQLF
FDADAYFAFVRRARAAGVRVPILPGIMPVTNVAQIERFTKMCGATIPQALRERLSAADGD
DKAVVRVGVEWATAQAEALLAGGAPGVHFYTLNRSFATREIFTRLQAERPRRRS
>A0A1H7QIP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. DSM 11652|TrEMBL
MLNFFQNLELQKICILVEYLTSTKSQQITRNIAGFPAFVAIADRVQSDDDMAPLEASQDY
PKSIDKVLHFSGKGRDIKDFELFLHQASSAQIRNLLLITGDKLKEHSYGDDQFERTRYLE
SINAVMSAKNYGGFNIGVAFNPFKYTEAEHYAQYLKLHKKVIEGADFIITQLGYDMDALK
QLKFFLKHYHYKQKILAYVMPLSLARANFIVKNKVAGIVITPYMLRVLAQEKKNGLAENA
YKRCAIQILMCKLLGFNGVHLSACEKSEEQKILQNYIEQYQDDDLEELEARWKALWQIKT
GNEFVPELTYDARNRH
>A0A1I0PD22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sp. YR573|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYEHLDPLMEFKPAFINVTYHRSEHMFKKK
SDGSFDKVEIRKRPGTVAICAAVMNHYNVDAVPHLICGGFSREETENALIDLNFLGVDNV
LVLRGDAPKNEASFEPEPHGHRYADELLQQVVHMNNGIYLEEDLQGGVKTKFCIGVAGYP
EKHFEAPNMQTDMNYLKRKVENGADYIVTQMFFDNQKFFDFVAKCREAGITVPIIPGLKP
ITSRKQLNILPRTFHVDIPADFSNEILKCKTDKDVEELGAQWLIQQSKELKAFGVPVLHY
YTLGKPNVILKAIQAIS
>A0A2T2SAN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QH_10_64_19|TrEMBL
MKVTEHFDQASEPLISYEIIPPKRGGSAEQMLEVVEELMPFDPPFIDVTSHSAEVEYKQR
DDGTWERCVKRKRPGTIGLCAAIEARFGIDTVPHLLCKGFTCEETEDALIELNYLGIDNV
LAIRGDDKGYKKSISENRSRNEYAVDLVQQIQDMNQGAYLEDLMNAEPTDFCVGVGGYPE
THFEAPNLAWDIMRLKEKVDAGADYVVTQMFFDNEYFFRFVDKCREVGIDVPIVPGIKIM
KRKRHLRTLPKYFHTEIPEELAAEIDAADPEDVEKIGVDWAIRQAHELMEADVPCIHFYI
MSSADTVKKVVEPLREPKEVA
>H5TCE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciecola punicea ACAM 611|TrEMBL
MKVIEHIDKATNPLFSFEIVPPPRGSSIQDIVDVVDMLAPYNPPWIDVTSHPSGAFYNEQ
EDGSVTRRIYKKRPGTIGICGVIQNRFKIDTVTHLLCRGFSKEETEDALIELNFLGIHNV
FALKGDGPNYNKKISAGRTTNQYASDLVSQIEDLKQGRFLDNINACSPLDFSVGVAGYPE
KHFEAPNLNNDIVHLKNKIKAGADYITTQMFYENQHFFNFVEKCRAVDITVPIIPGLKII
RTVKQLQSVPRHFYVNFPDDFVNEVLENPEHVVELGIAHAVKQTQELLDAGLPGVHFYVM
NDAKSVAKVIEKVGWGRVGAF
>A0A0S7XID4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KD3-62 bacterium DG_56|TrEMBL
MSELQQVVERGEFVITSEIGPPKGVDCSHALEEAATYFKGRAHAVNVTDNQSSVMRLGSM
VVCHLLADRGLEPVFQMTCRDRNRLALQSDLLSAAALGIENVLALTGDHNRLGDHPGSMP
VFDLDSITLLQAIGDLENGRDLSGAELEGDPPKFFPGAVVNPGAEPFEPEL
>A0A1V6SZM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium steckii|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRALVDMALEEAKVLGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRKQHGDYFCVGVAGYPEGHPADSFQDVQDPARDIPY
LVEKTKAGADFIMTQLTYDLEAYQKYESMLRNHESGLFKTIPIVPGLMPIHSYKILTRVT
KLSHVHIPDPIAKRMEELKHDDDAIKRAGVDVVSNIVGGIQELPSPGPRGFHFYTLNLEK
TVSFILERCDLIPPFSNIQDDSAFEELDGPPLGPQVRSLARRRASSINSQPHNRVIVDKI
SEHESSRDSVHEALANGAGLPAMPPGRGTTLQISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTSAVARRLWGHPVEQKDINTLFRRHVSGELHMVPWSEGGAEEGGAG
LNAETELIRPELLKLIDGRGWWTLASQPAVNGVRSDHSIFGWGPQREGFVFQKPFVEFFC
PNKDYVEILKPLFAKHGHDKLCWFATNVTGAFESSLPSQPADVELDDLGSNPESVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTETFLDTTKNDAWLVCVV
GQQFGAGVPAGSKEEEDEVKWMWRVLAGEVSE
>A0A0J7XVV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium czechense LL01|TrEMBL
MTLNDPAAPLYADLAGDARVSFEFFPPKTEKMEAQLWSAIETLAPLAPKFVSVTYGAGGS
TRERTHNTVARIASETPLAAAAHLTCVAASKDEIGEIADAYWDAGVRHIVALRGDPPEVG
GTFEPHPDGYKSAAELVDGLMKRHSFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFSPEAYFRFLDKTAAAGITADIVPGIMPVSNFAATQRMAAMCNTQVPNWMARLF
EGLDDHPASRQLVSATIAAELCRSLYAGGVRDFHFYTLNRAELSFAICHLLGLRAKAAVD
A
>A0A132EW55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomultivorans|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATRTICERLDT
>A0A1G3KJV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium GWB1_27_13|TrEMBL
MFIKNMFQKGKHVVSFEVFPPKKEDDVLKLYHTIEDLKSLNPDYVSVTYGAGGTTRDKSV
DIASHIKNHINLEVVAHLTCVNNTKNDVINVLDQLKSHNIKNILALRGDPSQGQTNFTKT
IGGFGYAYELVDFIKDKYDFSVAVAGYPEGHIETPDLDKDISYLKMKVEAGADVIITQLF
FNNDDFYKFRDIAVKKGINIPIIPGIFPILNYKSVQRITSLCGAKIPSNLVSILEKNQDN
IEEIEKIGIEYAIKQLDDLLNTDIEGVHFYSMNKSKEIKEIYNGVKNKIKRIEK
>A0A1G8C291|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseospirillum parvum|TrEMBL
MVTSASPSRATVSFEFFPPKTEAMEAQLWRAVTDLAGLHPSFVSVTYGAGGSTRERTHET
VARIRRDTDLEPAAHLTCVAASRDEVDAVAKAYWADGIRHIVALRGDPPEGVGERYTPHP
EGYPYAVDLIHGLKRLHDFEISVAAYPEGHPEATSPEVDLDNLKRKQDAGATRAISQYFF
DIDAYRRFMDRVAAAGITLPISPGILPVANFATVCKFSQACGTRVPDWMHARFAGLDDDP
QARARAAVEVACNLGRALLADGAGHIHFYTLNRADLTTTICQALGLTPDEG
>A0A178DWY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenochaeta sp. DS3sAY3a|TrEMBL
MHISQKLAQARQEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHSFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALRDAYQSGCTNILALRGDPPREKEK
WEATAGGFRYAKDLVVYIREKYGNHFDIGVAGYSEGSDDNNDVDQLIDHLKEKVDAGATF
IVTQMFYDTDIFLDWVKRVRAKGIDIPIIPGIMPIHTHAAFLRRANWTKCSIPQHWTEAL
EPVKNDDVEVREVGRGLIADMCRKLIDAGITHLHFYTMNLAQATRMVLEELELLPDVESP
LEKPLPWRQSLALNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPKSIKDLSDVFVRYMEGKLGSLPWSEQAITNEAGPIQEDLID
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVLVSPEHIAEIITRIERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHASISASRYVIQEVVDTWFLLNIVHNDFHVTRGIFPIFDGLKVEDMDRVLFDSSSAT
PTSNGREATNGTNGVNGNASSEEKPQSLIDAAKAAAVEVTNGIKNLAVSN
>Z9JKU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylella taiwanensis|TrEMBL
MIPISFEFYPPKNDDQRSQLDRTANRLHAFAPEYVSCTFGAGGSTLRYTSETVRHLSQHH
GFDAAPHLSCMGGSRQEIRELLKLYRAIGCQRIVALRGDLPSGMGHPGDFRYAADLIAFI
RGEHGNHFHLEVGAYPETHPQANNALSDLKYFKAKVDAGANAAITQYFYNPDAYFHFVDA
VQRLGVNIPIVAGVMPISNFDQLRRFSEQCGAEIPRWITKKMQAYSDDTKSVRAFGADIV
TALCERLIAGGAPALHFYTLNLAKPSTQVLQRLGY
>A0A7M2TE21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces chromofuscus|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFYAPKTAKGERSLWNALRRVEAVAPDFVSV
TYGAGGSTRASTVKETQQIVVDTTLTPVAHLTAVDHSIGELRNVIGQFADAGIRNMLALR
GDPPGDPMGEWVPHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVERFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCGTPVIPEVMPVTSVRMLERLPQLSNAHI
PSTLKERILTAKDNPSAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>D7E5Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalobium evestigatum (strain ATCC BAA-1072 / DSM 3721 / NBRC 107634 / OCM 161 / Z-7303)|TrEMBL
MPSFGQKLKSGEFVVTSEITPPKGSDISSVLKISDTLKGWVDAINITDNNRAVMRMSPLA
LGKILADTGHNVIMQMTCRDRNRLAIQSDLLGANALGIDSICIMTGDHTTKGDHPGAKPV
YDLDSVQLLSMVKKLTQGYDFSGNQLEGTPHFTVGVVSNIDISQKMQMMKLKKKAEMGVD
FIQTQAVYDVDQFKEFTESVKHLSVPIIAGIIPLKSANMARFMNNNIPGIKIGDDIISRL
EEAKDPVYEGLAISAETINEIRDICNGVHIMPIGKSLNTVTLLEMAGFSPE
>A0A0F7XSH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CCOS 191|TrEMBL
MSLLKTTLDANAFACILEFVPKPSAERFATLDTLMARTQLCGWPLTVAIGDRVGSALDMS
PLDAFNSLAEPVPALLHFSGKDRERRELLAQLQRMDAAGLDQLLLLTGDRLPGHVPGERP
VRYLESVAALQIVRQARPHWLLAAALNPFKYQEAEGGAQYSKAEKKLAAGADLFILQLGF
DIDKHQEAFDWMQRQPRPKPLMACIMALTEGRAGMLEHVAGVTVTPSMRALLAAEAAVSK
TYAKERANQRLALQVIGLKLMGYAGVHLSGIHEVAQFEALEQAIEVLEPQFSSLQDWAPA
WEAAWQAPGLTPVAFHPPGHAWRLGQRQITASNKEKVRYHLLSAMHHQLFSRTTALSKAF
GWAVTRPLWANPTAAQWLHQLERRIKRPMVGCDTCGSCRLEDTLYICPETCPKGLANGPC
GGTSLDRCEFGDRECVHSAKYRLAVSVGRTEVLRERLIPCVQVENRQRSSWPGWFETTTT
RQPTQNRSTTPKFNE
>A0A855QNZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MYb13|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVQAMGVHIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISTMCEDLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7L6PLE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. RHBSTW-00127|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIAQDYWHNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A6V8MBP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus curdlanolyticus|TrEMBL
MLKQAILNKQMGIITYGMSPPKESHTPEKITEISQKQIERLKGLDIDALILYDVQEESDR
IDTERPFPYMKSLDPETYSKEYLHELDIPKIIYRCVGKYSEEELTSWLKKDEGEQRYSVF
VGASSSQQEVQLTLSDAYRLSRQNSHNLTLGGVIIPERHMKKNDEHLRVVDKIKQGCDFF
VSQATYNVEASKNFLSDYYHYCREQELEMVPILFNIAPCGSTKTLEFMKWLGISIPKWLE
NELKYSSDVLDKSIQLTHKIFEELLEFGLEKGIPVGCSIESVSTRKVEIEASIQMVKDIK
ATIDKKRLQEAVR
>A0A1E8TRI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC071D03|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIGALQNMQDLAPHFISVTASNNKFNIKETTVRLADY
IQNDLAIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAQYIHQATHALFNHQPQGS
>A0A099GJN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sanguinis|TrEMBL
MSVRRTVPAVSFEFFPPKTLDQSFRLWETARDLAPLGPDFVSVTYGAGGTTRQLTHEAVT
ALATHYGLNVAAHLTCVEATRAETMQIVDDYAAAGVSEIVALRGDAPQGAAAWAPHPEGF
ASSVELIEAIAARGGFTIRCGAYPEPHPDSPDSAADVAFLKRKVDAGATSAITQFFFDPD
TFFRFRDACAAAGIAAPVIPGILPIQSWAGAKRFAARCGTSVPAWAEDAFARAGKPGEAA
LAREIAVDLCTRLIEGGVDRLHFYTLNRPELTAEVCAALGIEATEAAA
>A0A554WG09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidimonas aquatica|TrEMBL
MACPLSFEFFPPKTPEGAAKLRAARQRLYAARPQFCSVTYGAGGSTQEGTFTTVAEILAE
GVDAAAHFSCIGATRQRVRAQLAELQRLGVRRLVALRGDLPSGYGLGGEFTYARDLVAFI
RAEFGAAFHIEVAAYPEMHPQARSPQADLQAFAAKVAAGADGAITQYFFNADAYLRFVDE
ARAAGVTVPIVPGIMPITNATQLMRFSDACGAEIPRWIRLRLQGYGDDTASIRAFGLDVV
SALCDRLLRAGAPALHFYTMNQAEPTLAILDRLGLAPA
>D7HFW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cholerae RC385|TrEMBL
MTLGHREYKMGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKTLQ
PKFVSVTYGANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQ
NIVALRGDIPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRK
VDAGANRAITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVP
NWMVKQFEGLEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGV
RPQA
>A0A2K2TRH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. chh4-2|TrEMBL
MKIKDILGQGKPTLSFEVFPPKTEDKYESVEKAALEIAKLSPAFMSVTYGAGGGTSRYTV
DIAAALQNQCHVTPLAHLTCVSSTKEKVHHVLEELKEKNIENVLALRGDIPADGAIATDY
RYASELIYEIKQSGDFCIGAACYPEGHVESVNKTADIQHLKEKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVVAGIMPVTNVAQIKRICSMSGTYLPARFKAIVDRFGENPAAM
KQAGIAYATEQIIDLIANGVNGIHIYSMNKPEVAAKIQESLSEIL
>A0A1I0P3E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga arvensicola|TrEMBL
MKVTEHIAKAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPAFINVTYHRSEHMFKKK
ADGSFEKVEIRKRPGTVGICAAIMNHYNVDAVPHLICGGFSREETENALIDLNFLGIDNV
LVLRGDAPKNETFFEPDPHGHSYAIDLLDQVAHMNNGVYLEDDLQSGVKTNFCIGVAGYP
EKHFEAPNMQTDLSHLKRKVENGADYIVTQMFFDNQKFFDFVARCREMGITVPIIPGLKP
LTSRKQMTMLPRIFHVDLPTDLSTEILKCKTDKDVELVGTEWLINQSKELKAFGVPVLHY
YTLGKPKVVRQAVEAIM
>A0A4S1HHI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.168.01.1.1|TrEMBL
MIIKRIMHTLPDISATSVIPASIEASPAQVLGPASLAGLFPQGVRVYLTDTGAASQVKLV
DAAKHLRDLGYEPVPHLAARRIASRIDFEEQVKRLAGDAGVTDVLAVGGGVEKPEGPFTS
TIDMLSTGIFDRCGIRHIAIAGHPEGSPDFNDETATAALRLKRDFGERTDAAMRIVTQFG
FDSARFIAWAEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LARGHSPESIVGPIERHWRDNPQGPIRQIHVFPFGGLQASSDWLVSRGSWRTENADHAAA
TGSVAI
>A0A1H1NFF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraoerskovia marina|TrEMBL
MTVTIGAAPARPTISFELMPPRNPDAAPKFWETARRLVAARPDFVSVTYGAAGNDRSTAR
NVVGKLLAGTPVLPIAHLTCVGASLEDTESVIEDFLDEGVRSFLALRGDPPVNNPDWVPA
EGGPSSAVELVALLRRVEARRCAADVSTALRGAARPLTICVATFPDGNRDAGTTRTQEVA
RLLEKQQAGADFAITQLFYEASSYIEFVEEARAAGVTIPILAGILPMTEPRRLRRVEELT
GVPAPTSIVAELEAAADDDAARHALGVRRSVELARAVLAAGAPGIHVYTFNKHEAALDLL
EGVHLDGGGARATSPAPADLASGPWVSGESTTLTEGLAP
>A0A1E4L1T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium SCN 69-48|TrEMBL
MLPISFEFYPPKTDEQHSQFDRTVRKLKAHAPQFMSVTFGAGGSTLSHTPETVQRLRGEH
GVDGVPHLTCVGGSREEIRTLLKLYRALGCTRIVALRGDLPSGMARSGDLRYASELVRLI
RDEHGDHFHVEVAAYPETHPQAEDARIGLDHFKTKVDAGASGAITQYFYNADAYFRFVDD
ARAQGIDLPIVPGIMPIANFSQLRRFSEACGAQIPRWIDQRMRAFGDDADAVREFAADVV
AGLCRRLVEGGAPALHFYTLNLAKPTQTVLQRLA
>A0A1M6RDR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium lablabi|TrEMBL
MTEVAPPTPDGHRAFKTPDISFEFFPPKTEEMERSLWETIKRLAPLSPNFVSVTYGAGGS
TRERTHSTIARILAETDLLPAAHLTCVGAARGEIDEIVGRYHEVGVRHIVALRGDPPGGI
GTPYSTHPDGYRSSAELVAGIKRQHGDVEVSVSAYPEKHPESPDFDADIDFLKAKVDAGA
TRAITQVFFDNDIYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDDDPETRKLVAATVAAGQVQKLAKNGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A218ZSI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cuniculiplasma sp. C_DKE|TrEMBL
MQISNFQSKQKILKSVEIVPKRNENIDDLLAAREIFSDIADMVTAPENQMGRPGIDPLMA
LYIMTHGTNVIAMPHVTPRDKNTLYISSQILTSEKLGINHFFVIGGDPISGNLGREVREM
DTNETIRHIRKFSREQERDKEAIIGAALNPYRNSEEEIVRSKIESGATLFISQMCYNSEP
FKKKWIRQRKFKLFLGFMPILKKSNIESLSKMGVLLPEGLKSIIANSENLRDTSLKLIDN
LVSDMKGYIDGVHIMPIGNNEIAKEIMEVL
>A0A4Q0TX16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. PHL 2737|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLYQRNRLRRRPGTVAVAAAIQNKYNMTVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGHHHALELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIHWLKKKVEAGAEYAVTQLFYDNKKYFDFVERVHQAGIHIPIIPGIKP
FKKLSQLSMVPKTFKVDLPEELTQEALKCKTDEEACKVGIEWCINQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A822LKP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. CAG:131|TrEMBL
MKIRDLITQDKATLSFEVFPPKKDTDFADVEAAALGIAAFKPDYMSVTYGAGGSTKGHTI
QLAREIQEKYDVPTIAHLTCVCASKEGIKTALADMKNAGIENILALRGDIPKNYDGQVFA
EFSHASELVELIKETGDFCVGGACYPEVHPDSANKHEDIIGLKKKVDAGCDYLTTQMFFD
NNIFFNFMYRIREAGISVPIIPGIMPITRRVQVKNAVKLSGCNVPERFKSIVDAFGDTEA
AMRQAGIAYATDQIIDLMANGVKHIHVYSMNKPEVAAGIQKNLSEILKI
>A0A5I1B9L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Hvittingfoss|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A514WVJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrio sp. NC01|TrEMBL
MKVIEHINSAKDPLFSYEIVPPPRGRSYKDIVEIVEILAPLNPPWIDVTSHSSTAYFQEK
TDGSIQKRTLKKRPGTLGICGIIQNRFKIDTVAHVLCLGFSREETEDALIELSYLGIENV
LALRGDTPNFQKQIRNDRTTNNFAADLVTQIKDLSKGKFLDDLEDAHPLDFGVGVAGYPE
KHFEAPNLKLDIANLKKKVDAGADYIVTQMFFDNQKYFDFVSECRAAGITVPIVPGLKIL
KSAPQLKSVPKNFYIDLPDALVDEVHTSPQHAAEIGKRWAHKQVQGLLEAGAPGVHFYVL
NDVQCIADIVKSFK
>A0A385LFV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus rhodochrous|TrEMBL
MDRLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERLGPAFVSMTYGAGGSTRDRTV
RITGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWEK
HPEGLEYADELVRLVRDLGDFHVGVASFPEGHHRSPDLDHDTRYLVQKLRAGAEYSITQM
FFDVEHYLRLRDRVVACDAEQGLKPIIPEIMPITSLRSARRSLELSGSHLPPVLEERLRR
AAGDGPEENRAAVREVGIEVATEMCERLISEGAPCLHFITLNFARATGEVLDRLGYELEA
PAAVQPA
>A0A1G7QP35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella sp. 333MFSha|TrEMBL
MPAISFEFFPPKTDEQREQLDAAVTRLKGRGPDYVSVTFGAGGSTLSYTDDTVKRLRADH
GLSVAPHLSCMGGTKAEIGALLDTYKASGCRRIVALRGDLPSGMATPGDFRYAAELVGFI
REHSGDHFHIEVAAYPETHPQAENALADLRHFKTKVDAGADGAITQYFFNADAYFRFVDD
VTRLGVKVPVVPGIMPIANFSQLRRFSEQCGAEIPRWIVKRMQAHGDDAAAVRELGADVV
AELCRRLLEGGAPGLHFYTINRARATTSVLDRL
>E3D6G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis serogroup B (strain alpha710)|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A0S8HF00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonas sp. SM23_52|TrEMBL
MPDFRALIQNGSAHLFDGAMGTELYRRGVFINVSYDEVNLERPELVREVHRAYRDAGAEI
LETNTFGGNRVRLGHHSLGDRVHEINRAGAELARDVAGDDLYVAGSVGPLGIRIEPWGPT
AREEARAFFREQAEALAAGGVDLFIVETFSDLSEIEQAVLGCRDAADLPVIAQMTVQVDG
KTVYGADPPQIALRLDELGADVIGLNCSVGPAITLKAIQQMAEVTSRPLSAMPNAGLPRE
IEGRTIYMAAPEYFAEYTRHFIRAGVRFVGGCCGTTPEHIRAMAAQVRALSPRQRAVVPQ
AIKDVERRTAEPGLEPVPTPQRSQLARKVMAGELVASVEILPPRGCDLREVLDQVRQLKA
AGVDAVNVPDGPRAMMRMGVLATCSIIEREVGLETIPHYCCRDRNLLGMMSDLLGAHALG
LRNLLIITGDPPKMGPYPDATAVFDIDSVGLTNLVYKLNHGLDLSDHTIGQPTSFFHGVG
VNHASVDPEYEIHHFYWKVDAGAQFAVTQPIFDVEQFLQFLGKIEHIRIPIIAGIWPLVS
YRNAEFLSNEVPGVVVPDSVLERMRLASERGKEVAMIEGLAIARETVAELEPHVQGVQVS
APFGKVDFALQVFDALKGWAGRRR
>A0A828Y8W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira kirschneri str. 200802841|TrEMBL
MKKVSEIYGSTKGPVYSFEFFPPKTPEGDLKLMETVKELSLLNPDFITVTYGAGGSTRDK
TAQILSRISKNYSFPTVSHFTCVGSDKGQILETLKGIRSSGIVNLMALRGDPPKGEGEFK
KVENGFENATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVRNLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A437MB93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas crocodyli|TrEMBL
MNSVPFGQLEEARRALDTPLFADVAGDAAVSFEFFPPKTEKMEETLWASIQTLKVLKPRF
VSVTYGAGGSTRERTHNTVARIAKETDIPAAAHLTCVEASKAEIADVANAYWEAGVRHIV
ALRGDPPVAGTKFQAHPDGYQNAADLVAGLKSLHPFEISVAAYPECHPDSESAEFDLANL
KAKFDAGADRAITQFFFSPEHYFRFCDKARAAGIDAEIVPGIMPVSNFAATQRMAAMCNT
EVPAWMGRLFEGLDDHPASRQLVAATIAAEMCRRLYAGGVRQFHFYTLNRAELSFAICHL
LGLRADKAGLEKAA
>A0A133LEJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum|TrEMBL
MFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTISKEYG
IPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLVSYIR
SVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFLDKAR
AAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGILYASE
QIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A0E2NZK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNJC391B00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDTIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A540VCR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spiribacter salinus|TrEMBL
LQDLYEMRGRIPLSFEVFPPKSSEQCVALHETVDRLAPLAGRGFSVTMSSGGATRDRTVD
TATAIAARTGRPLMAHLVSLGLSRDEVLNTADDLWARGIRRILALRGDRPKGESGALPPG
FDHASELVAALRTRHDFEIAVAAHPETHPEAETPDQDIEYLKRKLDAGAGSAFCQFVLDP
AAYGRFLEDCGQHGIDVPIIPGLMPLERWPRLKRFARMNGAMVPDWLNELFARAETTPEL
EPYLAATMTTEHARRLIAYGAPEMHVYTMNRWPPSMALATVLGHK
>A0A0Q5QEP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia sp. Leaf354|TrEMBL
MTSPIASPTVVSRLSEPHSGPVPFSVEFFPPKDAPAEERLWRAVRIFERLRPAFVSLTYG
AGGGTRDRTVRIAGELARETTLTTVAHLTAVNHSLDELRAMVGSYADQGITNVLALRGDP
PGNPMGEWVKHPEGVAYAEELVRLVGELGDFQVGVASFPEGHHRSPTLDEDTRFLLGKLR
AGAEYSITQMFFDVEDYFRLRDRVVAADPEQGAKPIIPGIMPITSLASVRRMLELSGSKL
PADVDARLTAAAGNDEEANREAIRAVGIDLATEMSERLIAEGAPCLHFCSLNFARATTEV
LDRLGMNVLVP
>A0A4Z1ESK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrytis tulipae|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVYHIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAAL
EEVKNDDAAVRNIGKDLVAEMCRRILQAGVHHLHFYTMNLAQATRMVLDELRLTPSNQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLENNIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQQEP
DLTYYAVKKTGDVQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLNESFETSENGD
VDGVRFIEPQTVPLTNGEANGH
>A0A259FLH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium 17-64-34|TrEMBL
MTTRTFSFEFFPPKTTEGADKLRAVREQLAQLHPKFFSVTFGAGGSTRDRTFDTVREIQA
SGSEAAPHLSCIGSTRENIREILGDYKGQGIRHLVALRGDLPSGTMDAGEFNYANELVSF
IREETGDWFEIEVAAYPEIHPQARSWDADLANFKRKVDAGANAAITQYFFNADAYFRFVD
EVQVAIPVVPGIMPIGNYTQLARFSDACGAEIPRWLRKKLEAYGDDLPSIKAYGLDVITD
LCERLLAGGAPGLHFYTMNQAGPCTVIWQRLGLS
>M1UY35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanidioschyzon merolae (strain NIES-3377 / 10D)|TrEMBL
MNGTVEVECPKRPESRNSVAAFREPTVRELPQIKDKIAHCVEEGKRFYSFEFFPPKTEQG
LLGLYERIARLSRLEPLFVDVTWGAGGSTSDLTLELSGNIQKFFGLDVAMHLTCTNMEEG
MVDKALEEARKRGIRNIVSLRGDPPVGQEWRQCKDGFAHASDLVRHVRKVYGDYFCLIVA
GYPEGHPAGLLDGKLTYEQELNYLKEKVDAGGDLIITQMFYDVDQFLRFVRDCRSIGIQV
PILPGILPIQSYSGFKRMTGFCRTHVPEAVAETVERLKDDEEAVKNFGIEYGTEMCRRIL
NSKLSLGLHFYTLNLEKATVSILENLGLVPKFESVRALPWRPATIDGRRSEDVRPIFWAN
RPASYLLRTETWDDFPNGRWGDSRSPAYGELREHHLLGGGGLYTADQLERMREALGTPQN
LHDVSAVFVKFLRGETKAPFPWASEPLANETNLIAAALERMNWQGFLTINSQPRVNGAPS
TDVTVGWGGAGGYVYQKAYVEFFCSEERMIQLLDAVRGNTPEFGSLSIYAINSRGDLRTN
VRKPRTNAVTWGIFPDREVIQPTVVCPESFKVWSKEAFALWKQNWSSIYDPENGTPEERR
AYALIEHIRETFWLVNVVDNNFVTGDIFKLFARIG
>A0A6M4AR80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas lacunae|TrEMBL
MTTANSPSEARRAAASPMFADLSGDIGVSFEFFPPKTEKMNETLWESIKTLSPLGPRFVS
VTYGAGGTTRERTHATVARIASETGIPAAAHLTCVDASRAEIAEVAQAYWDAGVRHIVAL
RGDPPTAGSKFQPHPEGYASAADLIGGLRQIAPFEISAAAYPETHPEALSPQSDLDNLKR
KLDAGASRAITQFFHEPDTFFRFRDAAAAAGIDAEIVPGIMPVSNFAAIQRMSVMCGTDV
PAWLARLFDGLDDLPAARQLVAATVAAELCRRLYAGGVRNFHFYTLNRAELAYAICHMLG
LRPTVAKPEDIAA
>A0A7K7GGU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erithacus rubecula|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDSDRHERLREKMRRRQDAGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNYAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWREDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKDELERVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6G9Y2V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia brasiliensis|TrEMBL
MQSLRLHSRQRVPFSVEFNPPRDAAGEARLWRAVREFERMHPAFVSMTYGAGGSTKDRTA
RITGALAQETTLLPVAHLTAVGHSIAELRALVGSYADYGIRNILVLRGDPPGDPLGDWHK
HPDGVEYAEELVRIVRDLGDFNVGVASFPQMHHRSPDLDTDTAFLAAKLRAGADYSITQM
FFEVEHYLRLRDRLAAADPEQGAKPIIPELMPITSLRTVARAEELSGRALPAPLMARLRR
AAGTGPEEDRAAVREVGIELATELAQRLIDEGAPCLHFITLNFAKATTEVLTNLGYEVTA
APLSA
>A0A8F7T892|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia aeria|TrEMBL
MTTVHPALSYELYPPRSHASCESLLKTIAELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICMGHSVADLERSVRLILGLGVRGFLALRGDIPPEDTRPLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAAHLAGVQMPIIPGIMPVTSLTRLTKLCELAGLEVPRELAHRLETASDP
REMHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>A0A2E7II41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spongiibacteraceae bacterium|TrEMBL
MNNRYSFEFFPPKTDVGREKLKSVRAELNALGPEFFSVTYGAGGSTRDNTKNIVLAMKQE
GLSVAPHLSFGGDDEASMLELINSYKDAGIDRIVSLRGDLPSGMGATRLVYAKELVEFIR
KHTGDHFHLEVAAYPEIHPDAKSYQADIDFLKAKLDAGANSAITQYFYSIDAWHFFMEHC
QKAGIDKPIYPGIMPITNFSNLARFSRNCGAELPRWMTQKFESYEEGSEDAQQFGIEVVT
RLCEQLLAAGAPGIHFYTMNGVEPVKSIWKNLKL
>A0A3L7ZBD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. CH2-D42-20|TrEMBL
MKVIDLIRDSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A5C5VWB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium RAS1|TrEMBL
MRIRELLACGRPTISFEFFPPKDDNGLVALRDTIAALRELRPTYISVTYGAGGSTRERTI
ELVTRIRQDYQIEAMAHLTCVGAGQDEIRAVLERLAAARVDNVLALRGDPPRGDAAFTPH
PDGFRFASELAGFAKQRFGFCLGGACYPEKHVEAASLEDDLEHLRKKVDAGCEFLISQLF
FDNRFYFDFVSRCRAAGIGVPIIPGIMPITNVKQVERFTQMCGASIPEELLAELRRLQDD
PNSVLSLGVAHATAQCLELLQRGAPGIHFYTLNKSTATRTILTAIRAVYPPARTPAGTFV
>A0A3A6NI92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dethiobacter sp|TrEMBL
MSGLKPESKLEKVLSSGHFAVTGELGPPKSADVGTLKHHAEAMRNHVESYNITDNQTAIV
RTSSIGVAAALIQMGLEPNVQMTVRDRNRICLQSDLLGAVSFGVRNFLCLQGDHAKFGNE
PQSKNVFDLDSMQLLQAVRKLRDEGVFIGGEKLEHPLPRIFIGAVANPFADPFEYRPLRL
AKKIAAGAQFIQTQCIFDLERFEKWMEKVRELGLHKKVYILGGVTPIKSIGAARYMQNNV
SGMIVPDSLIERLKGAQDKKKEGLNIAVETIQRLKEIEGVAGVHVMAIAWEEVVPEIVER
AGLYPRPKVE
>I2NDP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis F0449|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLTKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFAHQPNLEGN
>A0A429G7R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC 05379|TrEMBL
MTTTVRRSTTTTLREVLARDLAAGTPTFSFEFFAPKTESGTRGLWDAVRRIEPLSPTFVS
VTYGAGGSSKDRTVEVTRRLATHTTLRPVAHLTAVDHSVAELRHIIGQYADAGVRDVLVL
RGDPPGDPNGPWIPHPEGFTHAHELVALVKDISDFSIGVAAFPERHPRSPDWESDIRHFV
AKCRAGADYAITQMFFDAEDYLRLRDRVTAAGCTTPIIPEIMPATDVRQIRRFAQLSNAS
FPADLAQRLEAARDDPAEGHRIGVAHATQMAARLLTEGAPGLHYITLNRSPATYEIHRNL
GVRG
>A0A4R7ZYP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2570|TrEMBL
MANGLPSTLPGGTPTIRELLASGDRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVVGAYAGAGVRNMLALR
GDPPGGPNQPWVAHPEGLNHAVELVELIRSLGDFCVGVAAFPDKHPEAASLEADAQVLAA
KSQAGADYAITQMFFGADDYFRLVDRAAALGCDMPVLPGIMPVTNIKQIQRMAELTGMAL
PTAVTDRLLAVEDEPTAVREVGIELATELCERLLAGGAPGIHFITLNRSTATRQVFLNLT
SSVVS
>A0A4R6WXF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dongia mobilis|TrEMBL
MSELHFDPAAPLPHLPGHSSGGRLERILRAGKFAVTAELNPPDSADPRDVYDRALVLSEV
CDAINATDASGANCHMSSVGICSLLTRAGYAVIMQISCRDRNRIAIQGDVLGAAAMGVQN
ILCLTGDGVQAGDQPEAKPVFDFDSTSLLKCIRGMRDEGKFLSGRKITVPPRVFLGGAAN
PFVPPLDHRAIHIGKKIAAGAQFIQTQYCYDVPMLRKFMAKVREQGLHEKAFFLIGVGPL
PSSKTARWMRSNVPGVHIPDAVIERMEKSKNEKAEGKQLAIDLIQEIKEIEGVHGIHVMA
YRQEEFVNEIIHASGVMKNRQPSRAPRPETPISISA
>A0A7L5T9T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Rer75|TrEMBL
MLAAGERSYSFEFFPPKNEAGERTLWNAIRRIEQYAPTFVSVTYGAGGSSRDRTIGLTKR
MAAETTLRPVAHLTAVGHSIGELRNIIGQYADAGILDVLALRGDPPGDPRGPWLTEPDGL
TYASELVALIRESCDFSIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFDAE
DYLRLRDRAAAAGCDIPIIPEIMPATDFRQVRRFAELSDAHFPDDLARRLEAAQGDADEG
RRIGVDHATAMARRLLDEGAPGLHYITLNRSTAALEIHRNLAPRPVRHTPR
>A0A3F3GWI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructobacillus pseudoficulneus|TrEMBL
MQKILDDYREQKQTVISQELIGDEKNRPRAAYYSLVNHSQDAAAFEQLLQRAEKLQEESQ
QQILLHLRASDIGRKTVAADFAQLKQHGLASFLVVGGDRQAGSDTFSSSLDLLRAVQAVG
LSADFLLASTLDVNLSSKKNVEMVVDQALAKEAAGAKILITQVFLSANDFLRVRQALKEV
GSNLILVAGVMANPSQQQLNWVEKQLGLAVSDQWRENPGQASQDLVATLQAQQVAGIHYF
AAPKVVRQR
>A0A7V3SJL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MTVKREQLRQILEESVLIADGAMGTMLQRLGVQAPYELANLVQPDAVRQVHRAYIEAGAR
LIETNTFGANRVKLATHGAGHLVREINLAAVRLAREAAGDVPVIVAGAVGPVGKPLAPIG
QIAPQEAGEAFREQIKVLLEAEVDLILLETFTHLDELRIALEQLRSLDSEIPVIAQKAFI
EDGETLAAGLPAHVARTLEEWGVDVIGANCVVGPQRMVGILQAMASATSLPLSVMPTPGL
PQYQRGEVTFEAQPDYFAQYGEQFARIGVNVVGGCCGTTPAHIRAVAERLHGVKPRARRV
PARVKEAVKPEELPRAEPSQLAGKLGRKYVIAVELDLPRGLDVTKVLDGARSLKEHGVDV
IDISDGARARLRMNPIAISHLIQEQVGIEVMMHFACRDRNLLAIQADLLGAHALGIRNIL
AITGDPALIGDYPTATSVFDIDAIGLVRILRRFNEGVDLAGNSIGMRTAFTIAVAYNPLA
YDQHTEDERLKRKAAEGAHLVYTQPIFDIAVLERAAEAASRVGLPLLVGVLPLRSARHAD
FMHHEVPGVWIPDPIRKRLAELDDADARRYGLDVAKEFALQARKVSQGIYLMPPFGNHKV
AEAVIDVLRG
>A0A2D6PDW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MIRGPGRYVRRVSGIPKRLGAKPTFSFEYFPPKGDAARQRALKTAIRLSARRPDFVSVTY
GAGGTDRSRTREMVADVCASHVTGRHRCPVMPHLTCVGHTRSEISELLEGYAAFGVSDVL
ALAGDPRPDLPPGDFRYAMDLIEQVREETDFGVGVAAFPEVHPRSPDRATDRRRLAEKLE
MADFGITQFFFDVDHYGRMVDELAGLGCEVPVLAGVIPVTNPASVKRFADMNGTDTPSGL
WQRLEDADGSERLRIAVDAAAGLVQELLDLGTPGIHLYTLNVPEAIEGVLDALGIGAPRA
GA
>A0A2E0T0Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MALFKKNEVPEIVESDEARAHREHLTRNFTIEVIPMKSLDNAREHLPAGAPLSVTASPVK
GLEETQRLTEEFQAAGFEPVPHISARMVRDRAHCAELAHWLRDNGLKKMFLVGGDQEPPG
EYFDAVLFLKDFLEQDHGLEGLGVTSYPDHHAFISDEKLHEALHAKQTLLAEAGLPGWCS
TQMCFDAEVIEAWLRKERAEGLTLPVHLGVSGVVDKAKLMTMGVRIGLGASLGYLKKNRA
AITKMLTSTSYDPNDLMMPLSNAALELGIEGVHMYTFNQIEATEQWRAEALAELTG
>R6LYY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:253|TrEMBL
MKPDFMSVTYGAGGGTSKHTVKIATDIKKQYGVTSMAHLTCVSSSEDTVRKQIELIRDAG
IENILALRGDIPEETEFPMPGQFKHASDLVYQIKNIAPDICIGGACYPEGHPEADDKTAD
IANIKKKVDAGCEFLTTQMFFDNSIFYNYLYRLREAGIFVPVIAGIMPITKKAQLARSIQ
LSGCCVPAKFKSIVDWFGDESQKMQQAGIAYATEQIIDLFANGIKNVHVYTMNNPEVALG
IQNNLSEIIGK
>A0A2D7MBP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIVQADKCLFSFEILPPLKGQDINAIYHTVENLLEFNPPFIDVTYHREEYQYVEK
AGGLLEKRVVRKRPGTLGICAALQSKYDVDMVPHVLCGGFTKEDTENFLIDLDFLGINNV
VALRGDAVSTEVYFKPEQQGHSYASELVAQINGLNKGHYLDEELKHSHATDFCIGVGGYP
EKHMEAPSLENDIAFLKQKVDSGADYIITQMFFDNQKYFEFVDRCRKEGINCPIIPGLKP
ISTIKQLSLLPHRFHVDLPQDLIQAVESCSSNTQVKEVGIEWCIAQSQELIQAGVPVLHY
YTMSRSDNIHKIAKAIFY
>A0A2N5L2A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia mannitolilytica|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRENIRSILNTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGDTFHIEVAAYPEYHPQSRSPRHDLDNFARKVKAGANSAITQYFFNADAYFQFVE
DARKVGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLESFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNTATATRAIWQRLGL
>A0A5J5IB41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium limneticum|TrEMBL
MPVIHPNWERPPVNMVDGYSLEMTAKDVESLREAAPAIARDTPVAVTFLPGEDFAARIAA
TKLVRSLGFEPMPHFSARRITSTTEFEDYLAAAVAEADVQRCFVIAGDPSEPEGPYFDSS
ALIASGAFERAGIRAIGIGGHPEGHPNMSPEQCWSVLTSKCSEIEARGMAPLIVTQFVFD
ADAVLAWLTELRARGISAPVRIGVPGPAGIKTLMRFAARCGVGASASVLAKYGISITKLI
GSAGPDKLVDRFERALGDEHGKVRLHFYPFGGLEKTVAWINDYARAH
>A0A3B9QHK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MPLFQSRGSNAAGQAIRKRLLLAARFEVIPLKNLEAQIEYLPEGASVSVTASPAKTLEDT
WDLSRKLFDRGFKPVPHLAARMLTSEAQLAALIKGLRDIEATELFLVGGDAPDPFGPFVD
SIEVLRAILDLDHDLKHIGVTAYPDGHSFISDELLRDSLHVKQQLLKSAGIACHASTQMC
FDPGVVRGWLERERAAGMTMPVHLGIPGAVDRAKLLSIGARLGVGASLRFLKKNRSTVAR
LFSPGGYDPNKLLGPLAGDLEPLEVDGLHVFTFNQIAATEAWRQASLQGL
>A0A022XX79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton soudanense CBS 452.61|TrEMBL
MHIKDKLALAEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMPRERVDDALQSAFKAGCTNILALRGDPPREKEA
WEQTEGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFLDWVKKCRQAGIKVPIIPGIMPISTYAAFIRRTNWVKCAVPKGWMEAL
EPVKNDDAAVKQIGKALVSEMCRKLLENGINHLHFYTMNLAQSTTMVLEELNLKPSTETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSVRDLSDIFVRFLEHKLDRLPWSESAITQESEIIKDDLID
LNNRGFLTINSQPAINGAKSSHPIYGWGPRNGYVYQKAYLELLISPALIDEVVRRIESNA
DLTYHCINKDGELKTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSASRKLIQNTMDTWYLVNIVNNDFHKTHDIFDLFKGLVLKDIDTEVSGTQQATE
PAENGTHSEDPASKSEKQAVSAN
>A0A2E0DLF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKIIDHLKNKKDSSQFTFEILPPLKGQNLESIFDAIDPLMEFKPPFIDVTYHREEYVYRE
LDNGLLQKHVIRKRPGTVGICAALQNKYDIDAVPHVLCGGFSKEETENLLIDLDFLGIEN
VVALRGDSLKSEVYFKPSVDGNSFASDLVKQIVDLNNGKYLDEEIQNNAKTNFCIGVSGY
PEKHIEAPSFDSDIHFLKKKIDAGAHYIVTQMFFDNQKFFDFQKKCLENKINVPIIPGLK
PISTKKQLNVLPQRFYVDLPDDLIKSVIKCKNNNQIRQVGIEWCIEQSKELKKAGVPFLH
YYTMGRSDNIKCIAESVF
>L8X3I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thanatephorus cucumeris (strain AG1-IA)|TrEMBL
MKVTEKIQQAEKDGRIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSELVKTCQGVIGIETCMHLTCTNMPQEKVDVALREAKANGCRNILALRGDPPSGQEE
WTTVEGGFQHGIDLVKHIRREHDDYFDIAVAGFPQTIQLPEAEAKQEMQWLKEKCDAGAN
FIFTQMFYDADMFIRWVKAARDAGITVPIVPGINPIQTWNGFIRATTLSGTDIPQDLMDI
LEPHKNNDEKVRELGTKIVSDLCRKILDAGIGIKGLHFYTMNLEKGTKMLLEELNLVPRV
ETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPPEEGRK
IWGTPTTIDDVKALFTKFCTQQIKALPWSDQPPTTEMLVIGQQLARMNELGYLTINSQPA
VNGARSDDKAFGWGPKNGYVYQKAYLEFFVHPSQLHALIKRIERDTNVTYYAINKQGDLK
TNSTSEGPTAVTWGVFPGKEVIQPTIVEAVSFMAWKDEAFELGCQWAKIYEPESPSRKLI
ENMMDEYFLVNFVHNDFHDREAIFRPFFADAGLQTNGDTETPAVNGVKHVNGLVNGHSTA
VRVFNTPSFPFVCTHALTSDTPCISPPVSFPRGPTDFIVNIIQGL
>A0A3N7BG25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Taibaiella sp. KBW10|TrEMBL
MKVTEHIQKAQGNTLFSFEILPPLKGENVQCIYNTIDNLIEFNPAFIDVTYHREEYVYLE
KENGLLEKKVVRKRPGTVGICAAIQSKYKVDAIPHILCGGFDKEDTENFLIDLDFLGISN
VLALRGDAIKSEIYFKPERNGHHYAHDLVAQIEAMNAGTYIDEYMETNNPTNFDIGVAAY
PEKHMEAASLQQDILYLKQKVDAGADYIVTQMFFDNDKYFQFVDKCRTAGINVPIIPGLK
PIATKSQLSMIPHRFKVDLPDDLVVDIIKCKDNAAVKQVGVEWCIEQCKSLKAQGVPALH
FYSMGKSDNIKTIAQAVF
>A0A150TXX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
MSRTRPEAPFLDAIRRSILVFDGAMGSLLYERGVFVTQNFEQLNVARPDLVKRVHADYVA
AGANVIETNTFGANRFRLERYGLVNEVRNFNLAGARIAREIAGGDAYVAGSIGPTGLVPG
VAKRDDLAAAAATFAEQAGALAEGGADLLVLETFRHLDEIKLAIEAARQAAPGLPVLASM
TFDTSGVVADGSEPERVARTLRDWGVDLLGVNCGDGPQLSLAMAERMATAGLPLCVQPNA
GLPRTVDGRLLYMATPEYFDVFARRMIQAGAAMIGGCCGTTPEHVKWMAKSARMLRGGAV
PEVTSRPHVTMDAPTGSEPTPLGERSPLAAKIAAGKFVVSVEVNPAPGLSPESALSAAKM
LIDNGVDVVNVADGPRATARMTNLAFCSLLVQRYGIEPILHVCGRDRNLIGQMAHLLGAH
AIGIKNLVIITGDPPKVGDYPEATAVYDLDSIGLLHMASTMNRGLDPAGKPIPGGKTSFL
LATGLEPGAPDLDKELARLERKRAAGADIIMTQPIFHQDLLEKVLRRIEHLGMPVLVGVL
PLVSYKNAEFLHNEVPGMQIPEEIRERMRKVPAGPEARKEGVKIAREMLFSVRDRVQGAY
LMPPLGKYELALEVLDGLKTS
>A0A844HFN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus litorisediminis|TrEMBL
MTTPAVSFEFFPPRNLDQSFRLWDTARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETLQIVADYAAAGVHEIVALRGDAPQGQDRFTAHPDGFANSV
ELIEAIAARGDMKIRCGAYPEPHPDSPDTAADVAWLKRKSDAGATSAITQFFFDADTFFR
FRDQCEKAGVTAAILPGILPIQSWAGARRFAERCGTSVPAWAEEAFAQAGKEGEARLAQE
VCVKLCEQLVAGGVDRLHFYTLNKPDLVLKVCAALGVTPKGALPNVA
>A0A6P1A342|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO1F2|TrEMBL
MTNPTKNSFRTAVESGEFLITAEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQQGIEPICQVACRDRNRIALQADLMGINALGISNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFEK
KLEAGAEFFQSQLICDFDRLEKFMDQIAAGTNKPILAGIFLLKSAKNAKFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSAVNDLVCK
>A0A1G7UY20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter thermohydrosulfuricus|TrEMBL
MLKNENLCTKLKKRKFVVTAEISTPKGVDITKTIEEARKLKGIVDALNITDCPMANMRMS
PIAVAHLLQDHLNIEAIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDEPSRGDTPQ
AKGVYDVDSVGLLKIISAFNRGYDYNGNKLDSPTEFCAGTTANPNDLRDEALEKLKVKIE
AGAEFIQTQPVYDEEILFKFIEKIKNFNVPLLIGILPLKSYKMAVNLNEKVPGIDIPEKV
LERLKDGGREEGINIAVEFIKRIRSEVARIHIMPLGSTNVVLEIISRVDDLVCDFAENNV
QMN
>A0A3B0TLP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MYKVRLWSVKHSRLLQTVYFMSAPALFSILRGVDKLFGRSLDPPITALEAGIKGFLFDCK
MCGDCILSKTGMSCPMNCPKSLRNGPCGGVRENSMCEVRPKMACVWVCAWEGAGRMKNAG
AINNIQFALDYRKTGTSSWLELARENQRK
>A0A5N6XA60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus sergii|TrEMBL
MFPFPLIGGPSSLFNYHLSRNFAGTDSGIKMEKITDKIAALPPDANYFSLEFFPPKTQMG
FANLQARLERMAQALRPLFVTVTWGAGGTTAQRSLELAEICQRQLQLTTCLHLTCTNMSR
ALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNRDFTFAVDLVRYIRQKHGDY
FCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTQAGADFIMTQLTYDIEAYTRFENMLR
THESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVQIPPQILSKLEEVKHDDDSVKRIGVD
IISSLVDGMRDIPCPGLRGFHFYTLNLEKTVSFILERCDLIPPYSEDFDAIEEGGDISAM
DGAQLRSLTRRRASSINSLPHNRVIVDKLHASEVSSKASVSHEAPATSAGMPAMPPDRST
TLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVPPAVAHRIWGFPVSH
EDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLIDGNGWWTLASQPA
VNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKHGHEKLAWFAANIK
GDFESSLPAQTSDADPIEMNPDNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD
EWRRIYPRNSATERFLNDVKDDVWLVCVVGQEFGAGTEMGSEEEEDEKKFMWRVLLNAKK
>A0A2G1VT99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leeuwenhoekiella nanhaiensis|TrEMBL
MKITDHIKQANGKTLFSFELIPPRKGRSIQELYDNIDPLMEFKPPFIDVTTSREEFVYIE
KEDGLLDKKITRMRPGTLGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIHN
VMALRGDAMKEQQYFEPTKGGHEYALGLVEQIADMNKGRYLNNVIETSDCSDFCIGVAGY
PEKHLEAPSLKTDLKRLIQKVEAGADYVVTQMFFDNKKYFEFVDMVRAEGIDIPIIPGIK
PIAVKRHLQLLPQVFKIDLPQDLIDAVDACKNNNDVRQVGIEWAIQQSRELMEGGAPVLH
YYSMGKSDNIQAIAAELF
>A0A428EL44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALQNMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2S7ZAX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella denticariosi JCM 15641|TrEMBL
MTLREKHKNGQFTITVELDPPKSSSAQKVFDQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHHEGIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAKAV
FEVDSMGLLNISKTLNSGKDMAGNDLDEPTSFYIGTTGNPGAEDLEIERQKLAAKIEHGA
NFVQTQPIYDLEQAKRYIDAMSGFNIPIMLGLIPLKSFKMATYLHEKVPGISLTQEILNR
VEKGGKEAGTEIAIETLEEIKKIASGVHIMPLNDIDTTLHIIDHV
>A0A139QC58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSSNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1W1DU07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKTSFEFFPPRTDKGKQSLVQVRQQLSVVQPEYFSVTFGAGGTTQEATLETVLDIQKKGA
IAAPHLSCIGSEKENIIKLLDQYKLAGVNRIVALRGDIPSGVRDIGDFHYANELVEFIRS
KYNDHFHIEVAAYPEVHPQAKNIYTDLQHFTNKVKAGADGAITQYFYNADAYFRFVDEVQ
KLGIDIPITPGIMPITNHAQLVRFSNMCGAEIPKWILERLKLYENDLDALSAFGTEVVTD
LCQTLKNQGVDSFHFYSMNRTQPSLDIAKTLL
>I2FMK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ustilago hordei (strain Uh4875-4)|TrEMBL
MANGIESPAIPPKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMAD
LGPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDRALKEAKQFG
CRNILALRGDPPAGQSEWEPHAAGFTRAKELVEYIRQQYGDYFAIAVAAFPEGHPEAFHG
PGKELERLKEKIDAGADFIFTQMFYDFDIFAKWLKEVRAAGINCPIIPGVMPIQTYGGFQ
RATARFGTLVPQYFHDALDPVKDDDQKVRDVGTRLVGEMCKKIVGSGLGISGLHIYTMNL
EKGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRRDEKIRPIFWANRAKSYVNRTETWDEF
PNGRWGDARSPAYGDVDAYGVKLRYSNQEAKQMWGNPTSLEDVKALFQNFCAGQVKALPW
SETPVARETSVISDKLTKMNELGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEF
FVSPEHLDALIARIEADPQITYHAVNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVE
SISFLAWKDEAYEIGRNWAKVYEPSSPSRKYLEEMFKRYFLVNVVHNDFKAADAIFEPFL
NAAKTAAVNGSLSSIGSTVADAAGHVTNSISSLTNGLSNGHTAAPAPAA
>A0A1C7WE38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. 14-2641|TrEMBL
MSFYHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGGGKPEMYAADLVTLLKDVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGAVVG
>A0A259S3W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halothiobacillus sp. 13-55-253|TrEMBL
MHTPLSCEFFPPKSDEGALKLRAVTEQLTSALKPEYFSVTYGAGGSTQDRSFATVQAIQT
ESGVPAAPHLSCIGSTRASIAAILDQYRALGIKRIVALRGDLPSGMRDPGDFRFASELVA
FIREHSGDWFHIEVAAYPEFHPQSANARADLLHFKQKVEAGADGAITQYFYSIEAYARFL
DDCEKLQVTIPIVPGIMP
>A0A8J6RKG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichocoleus sp. FACHB-832|TrEMBL
MPTIQNSMLFKSFRSAAEAGEFLITAEVAPPKGGNPVHMVEMAQTLKGRVHAVNITDGSR
AVLRMCPMAASVILLQHGIEPICQMACRDRNRIGLQGDLMGAHALGIRNILALTGDPVKA
GDHTDAKSVFDLESVRLLGLIKKMNLGFDWNDKPLTDGATDLFAGAAVDPQLASWSGLQS
RFERKLEAGAQYFQSQLICDFDRLEKFMDKIAAGCGKPIMAGIFLLKSAKNAEFINRCVP
GVNIPQDIIDRLAAADDPLQEGMAIAAEQVKLASQLCQGVHMMAVKREDLIPEILDMAGI
PRLNQLVSAGTEDERTNNKATADSVAL
>A0A7W6D5X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium azooxidifex|TrEMBL
MAHIDENPLGPHLPLDPQPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGV
GPMASAKTAKWIRSNVPGIHIPDSIIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGVLKGRKPWTREPNPVDTLVAERLEEARAGKEQNQQEMAEIAA
QHPH
>A0A7W8QYA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. AK017|TrEMBL
MKIIDHINNAKGKTLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNRYKVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDSSFIPTPNGHAYASELLQHVVDMNNGKYLHDDMESAEKTDFCIGVAGY
PEKHFESPNLDTDFKYLKHKVDTGADFIVTQMFFDNKKYKAFVDKCRENGIHVPIIPGLK
PITSSKQLISLPKIFHLDIPIELSEAVHGCKSEKEVKEVGIEWMINQCNELKAMGAPVLH
FYTMGNPEPTKKIAQAVF
>A0A831QQI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pricia antarctica|TrEMBL
MKITEHIAKAKGETLFSFEIIPPVKGHRIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKMTRMRPGTVGICASIKHKYDVDTVPHLLCGGFSKEETEYVLVDCHYLGIDNV
MALRGDAMKEEKYFKPTKGGHEYAIGLVEQLHNLNCGNYLHDTVESDHCADFCVGVAGYP
EKHLEAPSLKSDLKRLKEKVDAGAHYVVTQMFFDNQKYFEFVDAARNMGINVPIIPGIKP
IAVKRHLQLLPQVFRIDIPQDLIDAVDDCKDNKAVRQVGVEWCIEQSKELKEAGVPVLHY
YSMGKSDNIKAIAEKLF
>A0A8E3TP24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces chartreusis|TrEMBL
MLARDLAAATPTFSFEFFAPKTESGTRGLWDAVRRIEPLSPTFVSVTYGAGGSSKDRTVE
VTRRLATHTTLRPVAHLTAVDHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPNGPWIPH
PEGFTHAHELVALVKDISDFSVGVAAFPERHPRSPDWESDIRHFVAKCRAGADYAITQMF
FDAEDYLRLRDRVTAAGCTTPIIPEIMPATDVRQIRRFAQLSNASFPADLAQRLEAARDD
PAEGHRIGVAHATQMAARLLTEGAPGLHYITLNRSPATYEIHRNLGVRGRAVRAAA
>A0A6P2Q977|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia diffusa|TrEMBL
MKSIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAATATRTICERLAM
>A0A3F3B544|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae subsp. pneumoniae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7X9WTU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium psychrophilum|TrEMBL
MPVIHPNWERPPVNMVDGYSLEMTAKDVESLREAAPSIAPETPVAVTFLPGEDFAARIAA
TKLVRSLGFEPMPHFSARRITSASEFDAYLAAAVAEANVRRCFVIAGDPSEPEGPYADSS
ALIASGAFERAGIQAIGIGGHPEGHPNMTPDQCWSVLLDKCSEIEQRGMAPLIVTQFVFD
AEAVLAWLTELRARGIDAPVRIGVPGPAGIKTLMRFAARCGVGASASVLAKYGISITKLL
GSAGPDRLVETFERSLGEEHGRVRLHFYPFGGLEKTVAWINDYARAH
>A0A3N1D283|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinocorallia herbida|TrEMBL
MTRGFEVVCEIEPPTRPDLRRVRHQIGVLDAVADAFLIPDNHIGRATVSSVAVAHEVQAM
GATGIACLNARDRNLLGFQRDLLTAAAYGVQRFLFVYGDKPASGDRTGELTVRSMLDQAR
AATTDPVFAGHPRFQIGVASGMRPLPAWKQHADFVFAQVSYSLDDLLRWRETITIDAPVY
AGVMVLASATMARNLAATIPDITIPDTLVQAVEHDPDAGIAAACEHVLAIRDSGAFDGVH
LIPVSRYRQTAAHLEPLLHKPPKNPQ
>A0A2U1IRQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. B1(2018)|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLALYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVDIPIVPGIMPITNYNKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>B2J218|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MYHTHSPTAFRRAVQAGEFLVTAEVAPPKGGNPAHMIQMAATLKGRVHAVNVTDGSRAVL
RMSSLLASVILSQNGIEPICQVACRDRNRIGLQADLMGAHALGIRNILALTGDPVKAGDH
PDAKAVFDLEAVRLLQLIRKMNQGVDCNEKPLTDGALDLFVGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFERLEKFMDTIASGYKKPILAGIFLLKSAKNAQFINRCVPGVN
IPQHIIDRLAKAKEPFEEGIKIAAEQVQIARQLCQGVHLMAVKREDAIAPILDLAGIAPV
NQLVSK
>A0A1H0T5R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. NLAE-zl-C503|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A4Q9HPQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces kasugaensis|TrEMBL
MALGTASTRTDHAPTVRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSTAELRNVIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDADVAHFVA
KCRAGADFAITQMFFYPEDYLRLRDRVAAVGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEGVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A2A4B4R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas spermidinifaciens|TrEMBL
MVDPSEALHPAWATMPAIVTDGYSLEMTAKDFDALHAAAPGIAAETPVAITFLPGETIDA
RVAAAAAVRRLGFEPMPHLSARRIATHAELDTMLGRAVDEAGARRAFIVAGDPPEPAGPF
ADTLSIIRTGLLEKHGFRAVGVAGHPEGHPNMDEAGLWAALEAKLAALDERGLGALIVTQ
FGFDADPFIAWLEQLRARGIMAPVRIGVPGPAGIKTLLRFAARCGVGASAAVMTKYGVSI
TQLLGRAGPDKLVDALAARLTPAHGPVRLHFYPFGGLVNTVEWINGYQARAH
>A0A1H2DYZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopseudomonas salegens|TrEMBL
MTSPSAPVSFEFFPTKTDAGHAKLIAAAHVLAGENPEFFSVTYGAGGSTRDRTLNTVLQL
DQEVKVPTAPHLSCVGDSKEDLRSLLQQYRESGIQRIVALRGDLPSGMGQASGELRYANE
LVEFIRAETGDHFTIEVAAYPEAHPQARNYEQDLTNFVRKARAGADSAITQYFFNADCYF
HFVERVRKAGVDIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSDSIAAF
GTDVITDMCQRLLDGGAPGLHFYTLNQAEASLAVWRNLRG
>A0A2U1CBI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Simplicispira sp. 125|TrEMBL
MTATNAARPGLPVSVEFFPPKTPEGADKLRTVRQQLYALQPQFCSVTYGAGGSTQQGTFD
TVQAILQEGVDAASHFSCIGATRASVREQLATLKAMGVRRLVALRGDLPSGYGMGGEFHY
ASDLVAFIRAETGRDFHIEVAAYPEIHPQARSPEADLKAYAAKVQAGADAAITQYFYSGD
AYLRFVDEARRLGADVPVVPGIMPITSSTQLMRFSDACGAEIPRWVRLRLQGFGDDVASI
RAFGLDVVTALCERLRAEGAPALHFYTMNQSAATLEISRRLGLLR
>A0A2N5YAD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halioglobus japonicus|TrEMBL
MAKPRISFEYFPPKTDAGKDKLLNETTPALNELNPEFFSVTYGAGGTTRDTTLGVVSTMR
EAGVDVAPHISFGGDDEDTMAELLQTYKARGIKRLVALRGDMPSGMGTAMQLVHANDLVA
FIREKTGDHFNIEVAAYPEIHPESKSYDSDIHFLKKKMDAGANSAITQYFYNVEAYFYYL
DQCMAAGIDKPIYAGIMPITNFENLARFSRNCGAEIPRWICRKMEGYGDDLESVRKFGLE
VVTQLCQTLMDSGCPGIHFYTMNQVEPTREIYNNLGL
>A0A1F9VKT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFOXYA12_FULL_49_49|TrEMBL
MNIFRDKIINGGFSVTAELFPPKGNDASALLKKADFLKPFVDAINVTDNQRASMRLGSMA
VSRLIKEMGVEPIMQMTCRDRNRIALQSDLLSASALGIENVLILSGDHPLNGEYKDAKPV
YDLDTVQLLTAAGMLIKGTDLAGKNLSGTPSFCLGAVVNPTANPVELQIMMLEKKINAGA
VFFQTQPIFDVSQYEDFLGKVRPVTGAQKVRILPGVALLKSAKFVKFLLGLPGVNIPQAT
VDRIERAPDQLAEGIKICAETISRLRGIADGVHIMAIGMEEHIPEILRQAGIKSK
>A0A1E4N966|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus sp. SCN 65-179|TrEMBL
MTERTFSFEFFPPKTTEGAEKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETVCEIQA
SGSEAAPHLSCIGSTEASIRDILNAYKRQGIRHLVALRGDLPSGTMDAGEFNYANELVAF
IRKETGDWFEIEVAAYPEVHPQARSATEDLANFKRKVDAGANSAITQYFFNADAYFNFVE
DARALGVAIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLASIRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPSTTIWQRLGL
>A0A7X3TLQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MNGPARISLEFFPPRTEELTAMLKASLERLLPYGPLFCTVSYGAGGTTREGTARWVERIR
RGYGIDCAPHLTHVSHTRDEVREIVRDYVAQGVRRMIALRGDIPADGVSEEVRKRGYSST
VELITDLRAAGISEVMVGAHPEHGGGDSASLRRHLEFVKQKLDAGATLAITQFFLDNDRY
YRLRDIFAGAGIEHLLAPGIMPLHNYRQVFSFAGKTHVEVPAALGARFEQAGEDPDAVSE
IAEGFSLGQVRDLAENGVERFHIYTMNRAPLTAAICEALGLSAPGTQS
>A0A7W9CKC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas variabilis|TrEMBL
MLDVTQGQAVAPESAGSLLESFSLEMTAKDVVALEEAAGIIPPGTRIAIAFLPGETFEAR
LKAAERVRALGFDPAPHISARRIASEAELRGFLEGLVAKASIRRLFVVAGDPPVPEGPYE
DALSLIRSGMLNDLGLESVGVSGYPEGHPEIGSPALWQAMRDKRDALADLGISMTILTQF
GFDARPIVDWVEQVRESGIDALIRIGVPGPAGVKTLLRFAARCGVGASAKVMSRYGLSLT
QLMGTAGPDRLIEDLARRVDPERHGPLSLHFYPFGGIAKTAEWVSDFNARKAA
>A0A6P7QTM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mus caroli|TrEMBL
MNRQKAKVLPAGHCYPSLGMWAPEAGCVRLSVPPSIRNPAMVNEARGSGSPNPRSEGSSS
GGESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRFD
RMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCQQRPEEITGH
LHRAKQLGLKNIMALRGDPVGDHWEAEEGGFSYATDLVKHIRTEFGDYFDICVAGYPRGH
PDAESFEDDLKHLKEKVSAGADFIITQLFFEASTFFSFVKACTEIGISCPVLPGIFPIQG
YTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFY
TLNREVATMEVLKQLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQDW
DEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSG
EPNRHGYRVTCLPWNDEPLAAETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGWG
PSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTW
GIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNL
VDNEFPLDSCLWQVVEDTFELLNRHPTERETQAS
>A0A8K0Y1H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Szabonella alba|TrEMBL
MTVTPRISFEFFPPQTLDASFRLWETVQALAPLSPEFVSVTYGAGGTTRKLTHEAVATIG
RNYGLNVAAHLTCVDATRAETMEIVEAYAEAGVTEIVALRGDAPKGADRFMPHPEGFGSS
VELIEALAATGKFKIRAGAYPEPHPDAADTLADVRWLKRKIDAGATSAITQFFFEADTFL
RFRDLCVKEGITAPIIPGILPIQSWEGTKKFAGRCGTAVPLRLDEAFANAARDGREDLLA
LTQCSTLCTRLIEEGVEDLHFYTLNRPGLTRDVCHALGIQQPAVLEKVA
>A0A7R7E8R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. J8|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEAKLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDTVIREFADMGVKRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>A0A6N3J901|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. (strain W3-18-1)|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAADLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPNWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A7V6CBW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MTDNRPPRVSFEFFPPKTEAMEQTLWKSIQRLAPLQPRFVSVTYGADGSTRDRTHNIVTR
ILRETELVAAPHLTCVGATKEEVQAIARRYWEEGVRHIVALRGDPPAGSDHYEPYPGGYA
YAADLVAGLLEVADFDISVAAYPDVHPEAPSPEFDLDVLKRKIDAGAKRAITQFFFEADT
FLRFRDRCVAAGITAPIVPGILPINKFSQMLRFADMCGAKVPDWLHERFAGLDEDDETRR
LIAANTAIELVTTLQKHGVEDFHFYTLNRAELTYAICYALGLRPAGTDS
>A0A831KGY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MESQKRHNPVYSFEFFPPKTPEGVEKLRRVRARLAVLGPRFFSVTFGAGGSTRERTFETV
AEIQRESGIEAAPHLSCIEATREGVRAILSRYRDEGIRHIVALRGDLPSGSGTGGPREFR
YAADLVAFIRAETGRHFFIEVAAYPEVHPQARGARADLLNFQRKVEAGADGAITQYFYNA
DAYLRFVDECEARGLDLPIVPGIMPITNHNRLAHFSDACGAEIPRWIRKRLEDFGDDRDS
IRAFGTEVVSDLCRRLLEAGAPGLHFYTLNQAAPSLAIWENLGLGRIDTAGSPSAHRP
>A0A316NZS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriia bacterium|TrEMBL
MCLTRALCSADILLAYRRTRVTRGISVRNVFREALENGEFVVTCEMIPGRGAFEAYQEAD
HLKMKAIWETGLVHAISITDCPSGNPAISPPTVARRFAREGIPSIVHYTCKDRSRNMMQG
ELYAMQLRGLENLLIMSGDYQGSGFEGAGRPDFDLDPANALRLVSAMNEGLVYHGRDGDV
RETPAHFFPGAVVNPYKYREGESIPQYLKLEKKLICGAKFIIQQLGFDARKMQEQLFYVE
ERGYNVPMIANIFMLTKSAAQLMRKGTIAGCVVSDELMAELEEEAAIDAQTPGYARDRRI
ERAAKQIAIARGLGYAGVHIGGVGLDADTVTEVLERSSAYEDDWLACVRELSYGKPGGFY
LYESELDEDGKPTGLNTHEHAALDEDISGRKLFKGYGLSRLFHKLALAQEYDDEGSVVGR
SGLNGMLAWNMDRLDRKKGVNRAHGFEHTCKTFLYGCIDCGDCGLESVAYSCPMASCPKS
ERNGPCGGSMDGYCEVYPPTKEGGTRFCVHYMAYHRLKRAGKLDEYTSFITPPNDWTYWQ
RSAWSNYTHGRDNCAKRIPIDIGFDGSPGGLPKDEAE
>W1RYJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinomonas profundimaris|TrEMBL
MKSQLATKFQDPSRGIYFIGTTPPKSSLVEEQLVEISQKLLERLNGIDVDGLIVYDIQDE
TSRIDKPRPFPFMETHDPRAWSKRLHQQSEKPVITYKSVSSRSSEAFSGWLTEAWEEYGI
RDLVLVGSPSSNGDIKLPLPQAYDALKQSPHNFNLGGVTIAERHAKKGDEHLRLLKKSDS
GCDFFISQAVYNHQATADLISRYARECKKRGETPKRIILTFTPCGSAKTLEFMEWLGISV
PDATKHRILDAEAPLEESIKICRNALEQIIETALPLGVPLGLNIESLTNRKEEIDASIQL
YKLLKATLDLKLAEQSLTK
>A0A5Q0C5Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium grahamii|TrEMBL
MALNSDARRKIGISFEFFPPKSEEAEGQLWNTVSELQDWNPDFVSVTYGAGGTTKAPTLA
TVSRFLADTPLATASHLTCVGATKEETHGVIDSFRKAGVKHFVALRGDAPGGVGAPYQPH
PGGYANAAALVAGLREIGDFEISVSAYPEKHPESRDSAADIDMLKQKADNGADRALTQFF
FDNDNFERYLEKVRAAGINIPVVPGIMPILNLTQLKRFAGACGTVIPAFLDERFAGYDDK
PEERAKVAAEVAAEQIEDLARRGLAEFHLYTMNRAPLVSAVLTNLGFKREGAKNTGAAA
>A0A416ES01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. AF34-10|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDQLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A520XCX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MKTLRDAIRQKDLVITADLPLSPTTTAEDIESAALALRSVVDAVQIIDDREASGHMSSLA
AAAIALRAGIDPVLHLTARDRNRVALQAELLGAAALGLTSLVISRGEKLSKKEFLRGKGV
FDTNEARFMGMARRVGEESGLVSAPGFLLGTYVTVFAPADNWQAKRIGESLDTGVSILYT
QPCLNSRLLGLYMKKLVEKKILHRASVIAEVPLLGSRESARDYKKKNPIALIPDTTVKRI
VEADDPADAGFAACVEMLRETRSIPGIAGVTIRHTGSAQNVVAAVEAAGLAS
>A0A0B8QKP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis|TrEMBL
MNMTSNSKILSFEVFPSTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKF
ADYVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFRFA
SDLVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSF
YDFQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRD
AGIAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>A0A3B8MVT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacteriaceae bacterium|TrEMBL
MRITENLVPVSFEVYPPRGSLGLPQLHEAIKALQRALPNFISVTFGAGGSSTKDSLDVLT
FIR
>A0A1Z9XTW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp. TMED17|TrEMBL
MDALDSATAPTVSFEFFPPSTPAGWMNLDRRIAELVPLEPSFVSVTYGAGGSTRELTNDL
VVRLLEETKIPAVPHLTCIGHTHDEIDGILERYAEAGVTAILALRGDPPRDGSDPDAGHF
DHASDLVEHIRSFGDRHRYRFRIGVAGFPEGHPDTPNTLEGMNHLKMKVDAGADWICTQL
FFDNHAFLDWRDRCRIERIDIPIIAGIMPISTRRSVTRMAGLAAGTVFPASLQRSLARAG
RDDEDAVSEIGLHWATEQCRNLLDHDVDGIHFYTLNKSDATLRIHRSLGVRSARGLQRRG
P
>A0A522NSR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacteriaceae bacterium|TrEMBL
MSEQTYDDTGTGRCNVDTPFSFELYPPRSDAAAARLPQTIDRLAAANPDFISVTYGAGGS
SRASSLDVIRYIRQSTSVDPMAHLTCVGSSHAEANRLIHEFLDAGVRSFLALRGDPPVGI
AEGEYELGDLHSAAELVQLIHRVQAERVPYSEVSVPGLPGLRTVRSRRERVTIAVAAFPN
GHPRSRSASQDIDTLLAKQAAGANLAITQLFFHADDYLAFAQRAKQAGVEFPILPGIMPV
TSPARLRRMLELSGEDMPSELAIQLEIEPTEQGQREIGIDHAARFAEHLIAGGAPGLHLY
TFNQHETALTVLERCGILTTCTEKEPA
>A0A4Z1JPY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrytis elliptica|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHHIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAAL
EEVKNDDAAVRNIGKDLVAEMCRRILEAGVHHLHFYTMNLAQATRMVLDELRLTPSNQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLENSIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHEP
DLTYYAVKKTGDVQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLNESFETSENGD
VEGVRFIEPQTVPLTNGEANGH
>A0A1Q6V6Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium 13_2_20CM_55_10|TrEMBL
MHITDIMRENSPTFSFEFFPPKTPEAAEMLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQRTTKLDPIPHLTCVCHNEREVEGILLRYAKSAIGNILALGGDRPAGIAYDKSR
DSFQHAIDLVKFIRRFNESGAHRDRRGFGIGVAGFPEGHPATPNRLVEMDYFKAKVDAGA
NYIVTQLFFDNRDFIDFRERCTLNDIHVPIIAGIMPITSISGCKRIAELAGGARFPAKLM
RALQSCQNDPEMVRRVGVQYALEQCHDLLDNDVAGIHFYTLNRSDATRVIFDSLGFPHHR
NARALSV
>A0A182X3R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles quadriannulatus|TrEMBL
MYDNRVLFHLLLSKRLILSDTLGRWHPVQLAKHLHSHTPVLPLPASRPEQPLGAPAFVSK
IINCATALDSVMSVTSEPNNTMATTNTVTNAEQSNEDSLHTKLDRIFNSSTTSGPVPVHY
SIEIAAKDDFDIDQLKRLTPQPVFCALPWVSDDNLRYADDFLRSPTLQLTARLRENQYTV
LNNVSCYNITEQQVDQLLRSTGIRNLFVIRGDTVSPGQQFQNSAGLVQYLRTWQEQQPDH
RQLTIAVGGYPYGHHQSSSQTEELHYLQAKISQGANFLLTQTLYDAPSFLRYRDRCREAG
ISIPIIPGIYVPHSYRHLQALLNLTHIDLGPTVRDAFEAHAHDAPDQFQAFMVEYFVGVV
RELLQLNATTSSDPIKLVHFFTFNKFHLLQQVLEKLGEFFK
>A0A1H7APC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus reticulitermitis|TrEMBL
MSPTQISLELIPRTRSGLRAELATVREQFPAVSTVNIPDLTRFSTRSWEACAFGRPHFRT
IPHVRAIDLNPKEPLPMAGPLVAHGIEDVLIITGDAPSDMNRRVYPVDAEQAIRRFTREL
PHVRVYAGLDPYRQSFAQERDYLERKLEAGAVGFFTQPFFDLRLMDAYADLIPEGAEVWW
GLTNVTTEGSMNYWASRNRAVYPRSFEPTLEWNRCLAQAALKFARERSQHIYFQPIRTDV
VEYLGGIV
>A0A4Q7XQB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. BK239|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFYAPKTPKGERSLWNALRRVEAVAPDFVSV
TYGAGGSTRATTVKETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPSGLAYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDKDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCPTPVIPEVLPVTSVKMLERLPQLSNAHF
PAELKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A6J0BXZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neodiprion lecontei|TrEMBL
MDGACIAREILRKSKRGGKLHSRHCSPQHGPGQLLRKIGSPLLSTDVKRFSSSVCGYSLS
NMPANPSAGHSRNVFRGKNNVELSVTLAEKSSSNERFCSFELILHPDGREETYQQLFSVL
DQCNPLFYSITWHNVDNVSVENHPSLKLFERCSNITLLHLTAKGSTRGTVMHVLNRALTV
GKTNIFALQGDHDKLGVESTATDFSYAVDLVKFIRAEFGSKFSICVAGYPDMHPKSPSKE
SDLFYLKEKVNAGADFIITQIIFESQVFIKFVKDCRRIGISIPIIPGVFLIPDSKSLHNV
SKNCDAKIPDNLLQDLELIKDDDAAVQEYGMKLSTRVVKEIFQSGTAVGIHVFTLNRPKL
ALEFCKRLRFCRV
>A0A8J7C5B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfomarinibacter sp. MAG AM1|TrEMBL
MNALDLRRRLADHVVVTDGAMGSELLQRLPDGSSLDLAAHEHPQAVLDIHLAYIEAGAEL
IETATFGSSRPRLERVRVGDLTETVNATAVKLAREAREISGKDVLVAGSMAPLAGVLDLD
EPEGRAMIPVAHAEQAAILAGRGADLLVLETFFRVDELAIAVEAVRSVTDLPLIAMMTFA
HERPPHPYEEQGCLLDELADLDLLALGVNCAPGPMGAIEILRRVRQVRLPLAASPNAGTL
VRREGRILMPPATPSYLARFARQAVGLGTAVVGGCCGTGAEHIRAIAEAVRGLTPERRAK
TTVAAPDIAEAPEAVRPSSALAAKLARGRFVRLVQLDPPKGTNVDAMLEAAAAIAAHPDI
DGVDINSNPLARLRMDPLFLGQLVQQRTGLEAVPHITPRDASLMGLQSQLLGAWRGGIRN
LLAITGDPSQLGDFPGVHDVYHVDIFELVRALSRMAEGFDCAGNRIGDPPGFLIGVAVNP
AADDPAKEADRLRRKIDNGAHFAMSQVCFDWEAWDRFAELFNGELPIPTLTAVWPLRSLK
MALRLHHEVPGIFVPDDLLAALEEAGADAARVGYERAVQMLREAPDRAAGAYLIAPFKQP
QAILPVIDDAAAS
>A0A1C7GX26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides caecimuris|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESAFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSNTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVSQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A413DZD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides stercoris|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSIAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEKNGYHHAVELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTNEILKCKTDAEAQQVGIEWCVQQCKELMKHHIPSIHF
YSIGAVDSIKEVAKQIY
>A0A1B5CSX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 44 R 15|TrEMBL
MLAKNANDDAALLVYSGALRFFASKLAPTVQVGCTVGFRVSKGITMSQDRRYSFEFFPTK
TDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLESEVNVPAAPHLSCVG
DSKADLRGLLTQYKASGIKRIVALRGDLPSGMGMASGELRYANDLVSFIREESGDHFHVE
VAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFYFVERVQAMGVNIPIV
PGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFGEQVITEMCEQLLQGG
APGLHFYTLNQAEPSLAVWNNLKLPR
>A0A2N2YAX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-2|TrEMBL
MKVTKHIENANGKTLFSFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYQFKE
LPSGLLQKKVVKKRPGTVGICAGIQNKYEVDAIPHVLCGGFTKEDTENLLIDLDFLDIDN
VVALRGDALKNETYFKPEKEGNAFASELVNQISNLNKGIYLDEDLQNSSCTNFCIGVSGY
PEKHMEAPSMDSDIHFLKQKIKNGADYIITQMFFDNKKFFDFVVKCRKSGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNDAVKEIGNEWCVQQSKILIAAGIPVLH
YYSMGKSDNIKAIASQLF
>A0A0T1Q992|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Root431|TrEMBL
MALGTASVRSDRARTVREILAAGGTSYSFEFYAPRTAKGEQVLWNAMRRVEAVGPSFVSV
TYGAGGTTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNVLGQYADAGIRNMLALR
GDPAGDPLGEWIEHPEGVLYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVAKAGCETPIIPEVMPVVNVKTLDRLPQLSNAAF
PADVKDRILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A3M4ATG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. persicae|TrEMBL
MGSMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVL
QLENEVKVPAAPHLSCVGDSKEDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHA
NDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADS
YFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQ
AFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A0B4CHB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas nasdae|TrEMBL
MLLSPLGPVARAGSNRDAVRVSFEFFPPKTDEAEANLWKAIRRLEPLNPAFVSVTYGAGG
STRERTHRTVQRIITETSLRPAAHLTCVEASRDEVDEVIEGYKTIGVDHIVALRGDPPGG
AGIGGVYQPRADGYANATELTAAINRIGGFDVTVGTYPERHPESPSIDHDIEVLKAKVDA
GATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLQRMCGACGASIPDWL
KAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRADLVYAICRVLGVRET
AAVQ
>A0A3Q2DLJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinodon variegatus|TrEMBL
MVNQVQQVDGCWHSCKGDSSAASNSSGESSKESSRCSTPVLDADRIDRLREKMRKRIDSG
DHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGYLAKAKRLGLKNIMALRGDPVGDDWEEEEGGFSYAV
DLVKHIRSEFDEYFDICVAGYPTGHPEAESYQQDLQHLKQKVDAGADFIITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIHQAVGMCRELLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSANPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKNEQSVFEVFTCYITAQPNRIGQRVMCLPWNDEPLAQETNLLKDELEKVNK
RGVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVSALLKVLKKYEPRV
NYHIVNVHGRNMTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPDVLSDGAVS
E
>A0A3S1EW87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2C.T.Ca.TU.009.01.2.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDTVIREFADMGVKRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A2S9WV68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonlabens agnitus|TrEMBL
MKITDHIKQADQALFSFEIIPPVKGKSIQELYNNIDPLMEFKPPFIDVTTSREEFIYIEK
KGGLLEKKLTRMRPGTLGICAAIQNKYDVDTVPHLLCGGFTQQETEYLLVDCQYLEIDNV
MALRGDARKEEKRFESTDGGHKYAIDLVKQINDLNKGHYLHDVIEISCDVDFCIGVAGYP
EKHEESPSMKTDLKRLKDKVEAGAHYVVTQMFFDNQKYFDFVKAARDIGITIPIIPGIKP
IATKAHLQLLPKTFHLDIPQDLVDAVENCKTNKDVRQVGVEFCIEQCRELMAHDVPVLHF
YSMGKSDNIYDIAKAIF
>F8K0T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cattleya (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057)|TrEMBL
MALGTPSTRTDRAVTIRELLASGERSYSFEFAAPKTEKGERTLWNAIRRIEAVNPTFVSV
TYGAGGSSREGTVRATDRIVSDTTLTPCAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGEWVPHPRGLRYAAELVELIKESGDFCVGVAAFTEMHPRSTDVETDTRHFVA
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFSQLGNAPF
PPALAERILAVQDDPAAVRAIGIEFATEMCRKLMAEEIPGLHFITLNHSTASLEIYENLG
LHRRP
>A0A7C2SKP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MRFPEYFKDSTKPIISFELFPPKTDQGMKALLRVIPELIDLGPDYITVTYGAMGSTQKTT
LQIASLIKNDYRMETACHLTCVGASRTGLDEILEQIFTAGIRNIVALRGDPPIGEKTYVP
PPDGYSHAYQLVEHIRRFEKRKGQEPSGIAVAGYPEKHIEAPSMEMDIANLKRKVEAGAD
LIITQLFFDNSYYFKYVDKVRSAGINLPVVPGLMPIQSYRQIRRITSMCGSTIPPGLQEE
LDTTLDDDEKASDVGVRQCIRQAQDLLASGVPGLHFYVLNKSNQMKRIMEALRQ
>A0A382GPF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKYFKDALSTKDFVITSEIFMKPETDANSIKIQADVLRDYVDAILLTDNQSGQLHMSSLA
AGVLLLDAKIDPIIQLSCRNRNRISLLGDLLGCAALGMTNLSLIRGDRVPDVQPRPKAIM
DITATELIRMANKMKADDRIKSVGKFLLGGVVTPHGPKPGWQAKNVTEKIDAGAQFVLTH
TCLDMDLLRTYMQRMVETKLVRRINVIVGMAVLSSSEDAQWVRKNRPNVII
>A0A6V8K5B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytohabitans houttuyneae|TrEMBL
MGRLRVEANRYSHWVALGLPSVLPGGSQPSIGDLIAGPAPTFSFEFFPPKTAEGQPLLWQ
AIRELEPLRPSFVSITYGAGGTTRDTTVSVTERVATETTLLPMAHLTAVNHSVAELRHVI
GRLAGVGVRNVLAVRGDPPGNPMGEWVRHPDGVMYAADLVRLLKESGDFCVGVAAFPYKH
PRSPDIASDTDRFIEKCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPIVPGVMPVTR
MATIERSEQLSGAPFPPALLARFERIADDAEAVRRLGIEQCSEMCTRLLDEGVPGIHFIT
LNRSTATREVWQNLPAGARV
>A0A381NGX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MRIRDKIKRPRRPVVAYEILPPREKDGTLNSYAETISSLLSQTHIDAINIPEVREEERQG
DKPVKSLARAEPREFGQLLQDIVGVEAIVNRVVVHQVLEEELRWVEETNKKYEIENLIVV
GGESHKVDYPGPSVKEALKTITGQINSNGGNILCGGISIPRRKKESKNLIKKSQYGAEFF
TTQVLYDASKIMKMISHYQRRCQELNTFPRRVLLSFAPVSSQKNIDFLKWLGVDIPADTE
KYLNGRPGAMIDRSLDVAIEILNDTLDHIIKNKLVVPIGLNVEHIMSYNFQSSVEMLQEL
ARIYREFCIKADFYV
>A0A7V9RP14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MPLPAGPPTDVAPRDLAARIAADGPSFSFEFFPPKDDAGERQLWQTIRELEALSPTFVSV
TYGAGGSTRDRTIRVTERIASDTTVVPVAHLTCVGHTREELRAIVGELAAAGVRNMLALR
GDPPGGPGQPWVPHPGGLDHAVQLVELVRGLGDFTVGVAAFPDVHPEAVDAQADARALAA
KAEAGAAFAVTQLFFRAEDYFALVERARALGCDIPVLPGIMPITHLAQIERFTQLSGAVV
PGDIVSGLNRYADDPASVRAAGIEIATRLCDQLLDQGAPGLHYYTLNRSTATRRIHADLQ
TRIG
>A0A381REG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MLGSELEQVLRSGQLAVTAELSPPDSADPQEVYKRAALFAGHVDALNATDGSGANCHMSS
VGVCALLTRAGYSTVMQISCRDRNRIAIQGDILGAAAMGVRNILCLTGDGVQAGDQPDAK
AVFDFDSISLLETVRYMRDESQFLSERKLSTPPDVFIGAAANPFSPPVDYRPQRLKKKIE
AGAQFIQTQYCFDVPGLKDYMREVCNLGLHERCFILAGVGPLASARTAKWIRENVPGVHV
PDDLITRLEGAVDQQQEGVKICIELIQQIKEIDGIAGVHVMAYRQEEMVAEIIQKSGVLN
GRSPSVPSMLETFKT
>A0A382F1X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
EAVSFDHDINYTKLKVENGADFLITQLFYDNDDFFRFVDKARAIGIQVPIIPGVLPVLSS
NQIRKFTRLCGARIPSDLEMQLVKYENDDEGARAMGVEYATCQVQRLWDSGVSGIHFYVL
NRSYSVSKILDNLRLERSLL
>A0A7V9LPI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MRNKQRSQVMRRLLDNARYEVLPTASAEAAVVEHAPVGHTITVTASPAKGLEATLDLCER
LTGHGYHAVPHLAARMVNGRAELAEICERLVARGVDTVFAPAGDAEPGAGAYQSAVDLLE
DLTALGSPFQHVGVTGYPESHPSIGDDLTVQAMWDKRRYATQIVSNLCFDANVVGRWVRR
MRDRGITLPLLVGMPGPVERTKLLSMATKIGVGESTKFLAKNTSVFTRIATPGGWRPERF
LEKAAPTLGDPTALVTGLHLFTFNQVAETEAWRRRLLTELGAAPVAG
>A0A844TYY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella sp. 02P26C-1|TrEMBL
MTGPNTAALSLEFFPPRDIAAQERLVRTAKQLLAIQPRYVSVTFGAGGSTRAGTADTVRM
LQNLGCDAAPHLSCIGSTRQDLRQILTAYRDQGVRRLVALRGDLPSGMGGDAGELRYAAD
LVAFIRQEMGDAFHIEVAAYPEMHPQASSPQADLDHFVTKVNAGANAAITQYFFNADAYF
DFVDRAQSKGVTIPIVPGIMPITNHTQLVRFSEMCGAEIPRWIRLRLAEFGDDKASIRAF
GVDVVSQLCQNLLDNGAPGLHFYTLNQADAALAIWRELDL
>A0A7V9QZN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MTGLVRRCRYEVLPLAGTDEQVEQHLPPTSPVTVTASPRHGLEPTLEVTEALARRGFSAV
PHLAARLVHDAAHLADILQRLDEAGVSDVFVVAGDGRAPVGDFADSVQLLAAMSRLRRTD
PPAEPTRIGVAGYPEGHPLISDDDLSQALLAKQALSTYVVTQMCFEPAVVGRWVDRARRL
GLRLPVYAGVPGPVERLRLLRVAGRIGVGGSLRVLRKQRGGATLVRTGSYRPDRLLEDLA
ALGPPTHLSGLHVYTLGDVAGTARWRRELLDRLTAGGASGG
>A0A382EL43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKSTQLRLLDEMTYELIPLKNVHEQGEFLPQSSTISITCSPAKDIEATLELCENFLDKGH
TTIPHFAARMVESEEHVTRIVKRVEALGIETVFIIGGDADQRGPFTDAPGLLRSFLDNNP
SIKTVGIGSYPDGHPSIPESALAESLIKKQEMILESNLNGYMATQMCFEANTISSWLKNC
REAGITLPCHLGLPGAVDMKKLINISLRLGVGVSSRYLKKNRKSVFKLLSPRGYNPNRLI
IPISNDAEELDITGIHCFTFNAVESTEAWRTKTMDRLT
>A0A381Q0S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
VSQPQISYEFFPPQTEAGRTRLIETAEALAVTDPAYFSVTYGAGGSTRTRTYETVVKLME
NGMTTAPHLSWGDDSESTLVSLIEKYRELGVTHMVALRGDPPSGIGATARIRRAHSLVNL
IRRHFGNTFNLYVAAYPETHPDAISPEDDIRFLRKKIESGADGCITQYFFNADSYFYFID
RCRSHRIETPIVPGIMPITNYEGLVKFSDGCGADIPRWIRTRLAHLADNPEDLLAFGIEV
VTNLCERLLNGGAPGIHFYTLNKPHASVQIARNLGLG
>A0A382T2L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MIRSISFEFFPPRTPQLEAKLWQSIEQLAPIGPKFVSVTYGAGGSTRTATH
>A0A382LXT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MRLIRDILKEHQALGKTSVSCELFPAKTPEGEKALLEKIVPRLTEVNPAFFSVTYGAGGG
TRDKTIGIVDVIQSQYGVPTMTHLTCVGSAREDISRFLEDANSSGISNILALRGDPPPGQ
ESFVKAKGGFEFSYELVEFVKVQKRFSIGVAGFPEGHIACDEGREVDWDRLKVKVDCGAD
FIITQLFFDNSDFFAFRDYLRRKGMDRPILAGIIPILSTRQIQRFTGLCGAKLTAEITTR
LDELGGDDEAVSAFGIDYATRQCEELIANGVEGLHFYTLNKSRATVQVVKNLGLGQ
>M5QRQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus gonensis|TrEMBL
MGLLDDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIESGAEVIQTN
TYGANYVKLARYGLQDDVKKINEAAVELAKRAAKGRAYVLGTIGGLRSTNKSTISLEEVK
RTFREQLYVLLNEGVDGLLLETYYDFEELQTVLSIARKETTLPIIAHVTLHDIGVLQHGM
PLAEALTELERLGADVVGLNCHLGPYHMLRSLEEVPIPTRAFLSVYPNASLPQYRDGRFI
YETSEQYFEETARAFREQGVRLIGGCCGTTPKHIAAIARALSDRTPVYKKEVKQRHPIVV
QEEKQTTAPSLADIARTRRSIIVELDPPKKLGLTTFLEGAKALKEANIDALTLADNSLAT
PRISNVAVGTIVKQQLGMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRI
EKKIECGAHYFLTQPLYSEKQIEDVYEATKHLPTPIYIGIMPLTSARNADFLHHEVPGIT
LSDDIRNRMAMCANDRVQSTKEGLAIAKALIDAAFDLFQGIYLITPFLRYDMTVELVRYI
HEKERLAKERTVYYG
>A0A382X690|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
GSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVTNILCLTGDG
VQAGDQPDAKPVFDLDGISLLQTVTAMRDQGEFLSGRKLTTPPRVFLGAAANPFVPPLDY
RPVRLEKKINAGAQFVQTQYCFDLEQLRNYMVRVRDLGLIERCYILVGVGPMPSARTAAW
IRDNVPGVHIPDPVIKRLLDARDQREEGVRICIEMIQAVREIEGVHGVHIMAYKQEERVR
EIVAESGVLEGRAPWYPGVDNGH
>A0A8J7SUZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotellamassilia sp|TrEMBL
MTTGNKQHTAFSFEVLPPLRGKGMESIYCTIDKLMQFNPVCINITTHRAETIYSEMPNGA
YQKLSVRNRPGTVAIAAAIKERYHVHTVPHIICSGFSAAEIESELIDLSYLGITELLLLR
GDRAKDENRFIPSPGGHAHAIELCRQVNDFNEGKLLGGVVTNPLETPFVYGVAGYPEKHD
EAMNLDTDIEHLKAKVKAGAKQIVTQMFFDNSKYFAFVERLRREGIDVPVVPGLKPLTTL
NHCTMLPKTFHIDFPQELAREFEKCRSNADVKELGVEWGIQQVRELKAAGVPAIHFYTMN
AAFSTERIASATF
>E4T515|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paludibacter propionicigenes (strain DSM 17365 / JCM 13257 / WB4)|TrEMBL
MSVVEKIKSAKTTAFSFELLPPLKGNGIESVYRTIDALREFDPKYINITTHRSELVFKEN
AQGLFEQVAERHRPGTVAIAAAIQNKYKIAVVPHIICSGFTREETEYALIDLQFLGITDL
LLLRGDKGKHERDFSPTGHKNATELQVQVNNFNQGSFLDGSKMKSPIVPFSYGMACYPEK
HEEAPNLDSDLFYAKKKVDAGAEYLVTQMFFDNQKYYDFVEKCKANGINVPIIPGIKPIT
LMNQLTVLPKIFHTDIPEEFAAELRKCKTDAEAVEVGVEWCAKQAKDLIAQGVPSIHFYS
MMATQSVKRVAKDVF
>A0A348YCV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp|TrEMBL
MTKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALCA
RGDTDIAPHMSCIGDDKSEIAELLDLYKSLGISRLVALRGDLPSGQVDIGELPFALDLVK
FIREHSGDHFRIEVAAYPEMHPQARSFELDVDNLVNKYKAGANASITQFFYNADSYLYLR
ERLEKRGIDTVAQPLVAGIMPITNSSNLMRFADSCGADIPRYVRKQLADFGDDSKAIREF
GFEVVYRLCERLISEGVPAMHFYSMNKVEPNKRLIEALGLVHQ
>A0A2N0MF87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium MP-SInd-SRR3963457-G1|TrEMBL
MKITEGSFEATGHTSVICDFSPPRSGDAAVVGQAQIDADFISVAYNPGRAVRTNSAMLAA
AIQNSGKDAVFTLATRDMNKLALQTQLLGAQLLGVQNVVVVQGDPFGERDQTRVASVNDY
TPSGLIAAIAQMNQGQDFKESKLGQPTDFCIGATMDLGRGIEEEAQLAVRKVEAGAEFLI
TQPIFNVDHVARYRESFGYHAGKAGTVPIYLGLQILEKDGVLFSSVPESVRSELEDGRTG
VDIALELYRKFQKARLNNIYLMPPIKRGGARNYEAAKEFLGKIKKA
>A0A3D2IXJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp|TrEMBL
MTKPAFSFEFFPAKTELGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRNRTLDIVQALCA
RGDTDIAPHISCIGDDKAEIAELLDLYKGLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFAFDVDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTVAQPLIAGIMPITNSSNLVRFADSCGADIPRYVRKQLSDFGDDRKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLA
>A0A6C8F1T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Virchow str. SL491|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>K9XB04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gloeocapsa sp. PCC 7428|TrEMBL
MLNNLNGTSLNSLRTAIIQGDFLITAEVAPPKGSNPAHMVQMAQQLKDRVHAVNITDGSR
AVLRMSSLAASVILLQHGIEPICQIACRDRNRIGLQADLMGAYALGIRNILALTGDPVKA
GDHVDAKSVFDLESIRLLKLIHKMNSGVDCCDQPLSDGATDLFPGAAVDPQLASWSGLQS
RFERKLEAGAQFFQSQLITDFDRLEKFMDQIAKGCGKPIMAGIFLLKSAKNAQFINRCVP
GVNIPQHIIDRLEQAKDPLQEGVKIAAEQVQIARELCHGVHMMAVKREDLIPQILDLAGV
APVKKEPVMSITA
>A0A2T0UKM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycomyces artemisiae|TrEMBL
MTLGTPSVMPVKAAKIGDLLRSGEPKFSFELFPPRDEAAEGVLWRTIRDLERLGADYVSV
TYGAGGSTRLKTVDTTNLVNSETTLLTMAHCTAVDHSVAELRNLIGHFANVGVRNILAVR
GDPPGNPRADWVQHPEGILHARELVELIKESGDFSVGVAAFPDGHPRDVDWDTGVRYFVE
KCRAGADFAITQIFYDVEDYLRLRDAVAAAGCDIPIVPGIMPITNIKQIERFAVLTGMVF
PEALAERLRAVADDRDAVRDIGVEVATAMGARLLEEGAPGLHFTTLNHSRSTRRVWKNLR
P
>A0A402CZU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsulimonas corticalis|TrEMBL
MSDTMPFIEKLKAKTPTLSYEFFPPKNSGGWGTLYSSLGAIARQAPDFVSVTYGAGGSTR
QKTVELVGRIQSELGIETVAHLTCVGHSQGELRGILEQLEAAGVKTVLALRGDRPKNDPA
FVAHPEGFGRGCDLVDFIHRDFNFHIGCAFYPEKHPESSTMDLDIEILKAKQDVGADFAV
SQLFFDNDTFYQFRDRAHAAGVTLPLIAGIMPVTSLSQLPRFSELGGSQIPAKLTDFLGQ
GSDEEIVPRGVEYAAAQCRDLIDNGVAGVHLYTLNKSVSSVKVTQALRASGHLPKAAPGK
>A0A353XRI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp|TrEMBL
MNKPNFSFEFFPTKTDDGVTKLCQTFDTLNELSPAYFSVTYGAGGTTRQRTIGIVETLHN
RANTPIAPHISCIGDDKSVIGELLEHYKSIGINRIVALRGDLPSGQVGMVELPFAVDLVR
FIREHTGDHFHIEVAAYPEMHPQARSFDADIQNLINKFQAGANSAITQFFYNAESYLYLR
DALEKRGIDTTEHRLIAGIMPIINSSNLIRFADSCGADIPRYIRKQLADYGDDSKSIREF
GFEVVHRLCEILIAEGVPALHFYSMNRVEPNKRLVESLGLTSHSTQA
>A0A4Y3FQB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon|TrEMBL
MKYYSEFMRSLKSSEFTISGEIDPPKDVNPDEVKEQVKHLKGTVVAANVTDNPIGDVIMN
TLAPCVIMQDLGLEAIYQQTCRDRNRIALQSDIIGATALGIKNVLALTGDHPKMGNHPQA
KPVFDLDSVQLTGMLRKMREGSTLAGTELENPPEFHIGVGISPGVEPLEPEIIKLEKKVK
AGAEFAQTQVIYDVKILERLKDEASHLDLPILPGFAPLKSIGMAKFMIKYVPGIRIPEET
MKKLEESKNRVETSIEIVAELIAAARDMNFSGVHIMPVGMDVHVREMVERAGEI
>J3TED9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Carsonella ruddii HT isolate Thao2000|TrEMBL
MKHISFEIFPIKNIKENILFFNYLLDKNPKFITVTCGKKDNYDFIKKIKSYINKKIIPHI
ICNDIFLLIKKIIKFINLKIFEFVVITGDNSKFNSFNIINKIRILFGHTIKIYSGIYLEE
HKITKNILNEILFIYKKKKIGINMFISQFFYNYNLIEYCVNILKKIGINKNIILGIFPKK
NIKEILYFTNKCKIELPIWIIKNFNYINFKNYYFKNIKKIKMFHFYTFNKKKYVEYYLK
>A0A544T1Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacillus lasiicapitis|TrEMBL
MGLLDKLRTNMLTADGAMGTLLYAYGIEYCNEELNIQRPEIIQKIHQEYIKAGADIIQTN
TYGANAIKLARYGLENRVKEINEAAISIAKQAAAPGEQFVLGTIGGIRGIRKSEATLEEI
IQKVDEQVNHLLTGNPDGLLLETYYDFEELAATVTHLRKLTTTPIIAQVSMHEPGILQNG
LSLNDALQQLDTLGADVVGVNCRLGPFHTIQALEEVTLPKNAYLSAFPNASLLDIEDGRI
VYESEADYFGRAALLLREEGVRLIGGCCGTTPRHIEAAKKRIGHLSPLTTKVVAPKKPII
IREAEPNINEPLHEKAQNERTIIVELDTPRHLDTTTFMEGATKLYDVGVDAVTMADNSLA
SPRISNMAMGSMLKLQNNIRPLAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKI
GDFPGATSVYDVSSLELIQLIKQLNEGISFSGKSLKKKAKFSIAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVYTKEKIQEIYEATKHLATPIFIGIMPLTNIRNSEFLHNEVPGI
KLSDEVLERMRACGEDRERSTVEGIQIAKELIDTAAELFNGIYIITPFFRYDMSLELIKH
IQEIDSKKVRESSYVQTSN
>A0A482RSL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon|TrEMBL
MSKMESLKEDAEAVKQYGVDFGVALCRELVRRGAEGLHFYTLNSTQVVLPILDKLGYHKI
SRQEEEEKVLVAAV
>A0A1M3KMU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp. 66-22|TrEMBL
MNVPSDLRASRQFGDSRPPHQVSFEFFPPKTDAMEERFWDSVTKLAPLNPRFVSVTYGAG
GTTRERTLRMVSQIQSQTGVNAAAHLTCVGASKAEVDAVVRGYKEAGISRIVAVRGDPPE
GVGKPFVPHPEGYRSAAELVEGIRRIGDFDISVSAYPEKHPQAPSWDVEIDNLKRKFGLG
ATRAITQMFFENADYFRFVERAQKAGITQSIVPGIQPIHSFKQISGFASRCGASIPHWLA
ERFDGLDDDPETHALVASAVAAEQVLELVDEGITEFHFYTLNRSNLVLALARLLGVRPD
>A0A3N1R8E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. 3-2|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYREHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCEKLLAAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A3P3W7H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium macacae|TrEMBL
MKVTEHIQNANGKPLFSFEILPPLKGQNIQSIFDAIDPLMEFKPPFIDVTYHREEYEYKE
LPSGLLEKKVVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VVALRGDAVKNETYFKPEKEGNHYATELVTQISNLNTGIYLDDELQNSSATNFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKSGASYIITQMFFDNKKFFDFVAKCRKEGITVPIIPGLK
PIGTKKQLNLVPHRFKVDIPDELIMSVVRAETPEAVKQIGIEWCINQSKELIKEGISVLH
YYSMGKAENIKAIAKEVF
>A0A2A6PT10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. Y36|TrEMBL
MSGAMTDLTIPARADGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVT
YGAGGSTRERTHSTIARILKETTLLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRG
DPAGGIGTPYSSHPDGYQSSAELVAGIKKRHADIEVSVSAYPEKHPEARDFDDDIDTLQA
KVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARAFVTRAGTTV
PDWFAAKFEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLG
IRAKSAQKAA
>M1SJQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|beta proteobacterium CB|TrEMBL
MELSVEFFPPKTPEGESKLHLVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVRDMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
AETGDWFHIDVAAYPEGHPQAKSPATDVDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YELGVTQPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDTASIRAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLSLNK
>A0A1S8LPM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium roseum|TrEMBL
MIREYIKNNILVTDGAMGTYYSKITGDYNNFCEFANLNNPKVIFNIHKEYIDAGAKFIRT
NTFSANTLTMDISKEELRNIITEGYKIAKKAAATKDNVFVAADVGPINKFEVGKPVEYII
EEYKLVVDTFMELGADIFVFETLSSIDCLEEIFKYIKSKNKYAFILTQFAVMQDGFTREG
ISANSIVNKMNSIKNIDAYGFNCGSGPAHLYSVIKNLKLLGDTISALPNSGYPELINERM
VYVDNPDYFADKMSMIKNVGIKILGGCCGTTPRHIEKLVEKLKTNVKQVEIKAIKKEEKP
NKKREKNKFWEKLVKDEFPIVVELDPPFNIDIDKIMYAAEVCKKNNIDLVTIADSPMSKV
RVDSIMIASKIKRELGIEVMPHMCCRDKNVNAIRASLLAAHIEGIRNILAITGDPVTGID
KVNTKSVFNLNSFKLMNLISEMNKEVFKHDKINIGGALNLNVLNKKIEVSRMLKKVDNGG
TFFLTQPIFEESTIEFLANLKRDKGVKIIGGILPLVSYRNVQFINNELFGVNIPKEYVER
FKIDMSREEAETVGVDLATELIHKIKKYVDGIYMVTPFNRIEMVMKILKNIRK
>A0A8G0KMQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium columnare|TrEMBL
MKVTEHIEKAKGKTQFSFEILPPLKGQNIQCIFDGIDPLMEFNPPFIDVTYHREEYEYKE
LQNGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGNAYASELVSQISNLNKGIYLDSDLQNTNTTDFCIGVAGY
PEKHMEAPSMDSDIHFMKQKIKNGADYIITQMFFDNQKFFEYVEKCRNAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLVMAVVKAKDNEAVKQIGIEWCIQQSKELVKAGVPFLH
YYSMGKAENIKAIAEEVF
>A0A8E2DQM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Obba rivulosa|TrEMBL
MKFIDRVRQHAAGHPFFTLEFFPPKTDLGFGNLLSRMSRLAALNPLAVSVTWGAGGSTKD
RSLDLAAFTQSSGLDTILHLTCTNMVQGTVDEALREAKSRGIENILALRGDPPRGEEYWI
PTDPRFSHAVDLVRYIRSSPEFSSNFCIGVAAYPDGHADHETDEASELECLKQKVDAGAD
FIFTQLFYDIDNFIEWVKKVRQKGITVPIIPSIMPLQTYASFLRMTKLAGTRVPPELMAD
LIPIRHDDQLVKDYGVNLAVKMIRRLAAEGGIPGVHLSTLNLEVSVIRILEELGWAGGAM
HTSNRLIADTPQESASRVITPHCATDSAATMLVMAGPQTEGEAGKGELNNAVGWDDFPNG
RFGDFKSPAYGNTDQWGSTGLSRKQALEQWGSPKTVDNLTEIFLRHLQSRIATTPFSPTP
LSPESLMIFPHLERLTRRGWWTVGSQPAINGAPSTDEVVGWGPRGGYVYQKCFVEFFLEQ
EDVDKLEQKVREEGNSWVHYFAGNVQGECRTNVPDDGRNAVTWGVFPGHEVVQTTIIEKE
SFLSWKDEAFSIWAEWASFYPPDSPERQLLEGVRNQRWLVSIVHHDYMDSNALWTFLFGK
EKPLV
>A0A3N2GP56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis thermoflava|TrEMBL
MRGRFAEQLSERVLVFDGAMGTVLHVAGNSLDRALPELNLSNPELVSTIHESYVAAGADV
LLTNTFGANRLRLAEHGCSVSARDINLAAVRLARQARRGVHRTIFVAGSVSPAVSSSSRA
GVRADERAEVVREQVQALVDGGVDLLVLETFGHLDELVEAVTVAAEVTDLPVVAQATFTS
DGLTPAGETPREVVKALTGLPVTAVGANCTVGPQHMLAILDELRDAGDLPVGVHPNAGMP
RRTGRRFTYPVARAHFGRYARRFAEHGAAMIGGCCGTTPGHIREVVARLADLRPRQANPV
TAVPKPRPAPPQSPLARRLARPGFVLATQVTPHGEPEDVERVRGAGLALVRGNFGEALRL
EREAGVDTITTVTAWDRSLAALQADLLGAHAFGLRTVVCETGTPVPLGDYPGADGIWEVD
SVGLIGLLAGLNSGRDHTGLTLATRTAFHIGARVNPGAEDPDAELSRTKAKIAAGAQFLI
TRPVYELEGLSRLVTELSGVDIPVLVAIAPLSGFAEAEYLAYEVPDVTIPPRALSELEAA
GKREAEVGLALAAELIDGARDLVRGAVVVADEHPGKIDSLLRQEKSALQL
>A0A7G3E6Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus thiaminolyticus|TrEMBL
MKDLRQVLQGEIIVGDGAMGTYLYQLGYPVGISYESLNISEPERIRDIHREYVSAGARLL
ETNTFTANREKLSKHGMEKQVKAINRAAARLAREAAAGQAYVVGALGSIRAGKRENIETE
QVKRDYTEQLSALLEEGVDGIMFETFYDMEEMKLAVQIVRALDDRIPIICQFAVEESHRT
KDGLRLLDAFRLLREEGADIVGLNCRMGPNGLMRAMEEVTGRLALPMSAFPNAGLPDYVD
GRYNFVATADYMAESAVRFAELGARIIGGCCGTTPEHIQAIAQALAEAEAPVLPTLAEEK
ALAQAVPPLEIGEIDDAPLSGQGKAASGPSLVDTVRERHTVIVELDPPRDLDIAKFMLGA
QALKDAGADALTLADNSLAVTRMSNLALGYLALDKVGIRPLIHIACRDRNLIGTQSHMMG
LHALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEIIRMIKQLNAGLAFSGKVLKQRANF
VVGAAFNPNVKHLNKAIERLERKIEAGADYIMTQPVYDAALIERIAEGTKHLKLPVFLGI
MPLASGRNAEYLHNEVPGIHLSDEVRERMKGLEGESGRREGVAIAKELLDVAMKHFNGIY
FMTPFMFYEMTAELTEHVWQKAERPTAPLYRHT
>A0A1J5I7I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium CG2_30_58_14|TrEMBL
MKTNSRVEKILAGGGFVVTSECGPPRGADPEVVRQKGELLRGVVDAVNVTDNQTAVVRMS
SLSACAILKGMGLEPILQMVCRDRNRIALQSDILGAAALGINNVLCLSGDHQKFGDHPQG
KNVYDIDSIQLIQTVCRMRDEGRFLGGEEIKGKPLMFVGAAANPFADPFEIRAARLGKKM
RAGCEFIQTQCIYNMERFSRWMEMVCERGFHEKCAVLAGVTPFKTAGMANYMKKNVPGMD
VPDEMIARMKGVPKEKQAEEGIKICVETIERLREIPGVRGIHIMAIEWETKVAEIVKAAG
LLPRPEIE
>A0A1V6M3A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Brocadia sapporoensis|TrEMBL
MIKNSSDAKSDSNLEKILRSGQFAVTAELGPPRGSDRSAIEKKAELLRGYGDAFNITDCQ
TAVVRMSSIAAGRIVLDAGLEPIIQMTCRDRNRIAIQSDLLGAAALGAKNLLCLTGDHQK
FGDHPMAKGVFDIDSIQLIHMVKTLRDESKFQSGQELKTAGPRFFIGAAENPFADPFKFR
AIRLAKKIAAGADFIQTQIIYNTKKFKEWMKMVADMGLHEKAFILAGVAPLKSVGMARHM
KHNVPGMDVSDEIINRMTAASAAKKGKEEGIRICLEVIEQVREVKGVAGVHIMAVEWEEA
VREIVQQAQLYPRPRLENL
>Q2L158|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella avium (strain 197N)|TrEMBL
MTDSTSPAISLEFFPPRDIAAQERLVRAAKQMLAVQPSYVSVTFGAGGSTRAGTEETVRT
LTNLGCDAAPHLSCIGSSREQLRSILDHYREAGVRRVVALRGDLPSGMGGDAGELRHAVD
LVRFIREETGDWFHIEVAAYPEMHPQATSPTADLGHFVSKVQAGANAAITQYFFNADAYF
DFVDRAQARGVTIPIVPGIMPITNYSQLSRFSEMCGAELPRWIRLRLAEFGDDKASIRAF
GVDVVTKLCQTLLDHGVPGLHFYTLNQSEATLSIWKNLQR
>F9N3F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. oral taxon 780 str. F0422|TrEMBL
MSETIQQKRPTLSYEIFPPNTQVGDEKIITVLDELKSLKPEFISVTCSNKQRNIEETTIK
LSNYVQNTLHIPTKAHLPAIYLSKKQVRSVIDQLDQLGIHKLLALRGDILEDLPPVGDFK
YASELVHFVKDYAPHFQISGACYPEVHPDSPNQLQDIKFLKEKVDAGCELLVTQFFLDNN
VFYDFQEKCALAGIDVPILAGVMPIINRNQALRLLTSNATAIPRKFKAILDKYEHDPIAL
RDAGLAYALNQIVDLVTEGVSGIHLYTMNQSNTALYIENAARSLFSSPIYENQ
>A0A246GLH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium columnare|TrEMBL
MKVTEHIEKANGKTQFSFEILPPLKGQNIQCIFDGIDPLMEFNPPFIDVTYHREEYEFKE
LPNGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKAEKGGNAYASELVTQISNLNKGIYLDDDLQNTNATDFCIGVAGY
PEKHMEAPSMDSDIYFMKQKIKNGADYIITQMFFDNQKFFEYVEKCRNAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNEAVKQIGIEWCIQQSKELVKSGVPFLH
YYSMGKAENIKAIAGEVF
>A0A2M8RT73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caviibacterium pharyngocola|TrEMBL
MSYAKEIDTLNQHLTDINGKINVSFEFFPPKNEKMENILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKRIKQETGLEAAPHLTGIDATPDELKRIAQDYWDNGIRRIVALRGDEP
KGYDKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPSWLAKMYEGL
DDDQTTRNLVAASVAMDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGVRPTL
>A0A292SJZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Gastranaerophilales bacterium HUM_21|TrEMBL
KTLKSLDVKNILALRGDMPENQKIYNDFKYASELVEYLKKESSLSIAVAGYPEGHKECES
IEKDIQYLKQKVDNGADVIFTQLFFNNSHFISFVEKCEKQNITVPIIPGILPVTNYKTLE
KMSTLCKVEVPAKMAQVLEKHKDDKDYIKQYGIEYASLQCKELLETGVKGLHFYTLNKAY
ATSEILKNILYTRTN
>A0A552QPL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 130|TrEMBL
MELVTDRPTFSFEFFPPRTAQGERTLWQAIRRLEPLGPDFVSVTYGAGGSSRDRTIDVTK
RLVTETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPKGEWTAHPDG
FHHAYQLVELVRSLGDFTIGVAAFPERHPRSPDWESDIRHFVAKCRAGADYAITQMFFDV
EDYLRLRDRVEAAGCATPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAQHRPDI
AYEIGVAHATLMADRLLAEGAPGLHYITLNKSTATLDIHRNVMSTRSLHAS
>A0A7V4KI95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
AKKYLKEKVDAINVTDNQSSVMRFGSLGMCILLKQNGFEPIYQITCRDRNRLALQSDILN
AAAFGIENLLLLTGDHTVLGDHKDAKPVFDLDSVSLIYTVKRLMEGYDLAGNKLDGDPPS
FCIGAVVSPEAEPLDPQLFKMEKKILAGAEFFQTQLVFNPEKFINFMEIVRKNFGKIPVL
AGITILKSVGMAKYMNENVAGVYVPEHLIEELKKDKEKTKAGQTGVEIAAKIINDIKQYC
DGIHIMPLGWDDKVPQVLSLAGL
>A0A7L1EPF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oenanthe oenanthe|TrEMBL
MVNETQHACSASSSSRSDGGSSSGSESSKDNSRCSTPVLDSDRHERLREKMRRRQDAGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYETDLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRSYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWREDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDELERVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLRKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7V8FYE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum frisingense|TrEMBL
MSKHNFSIEFFPPKTAEGAEKLRATRARLAALQPKYFSVTFGAGGSTQQGTRDTVLEIIG
EGHDAAPHLSCIGSSRASLRAILDDYKANGIKRLVALRGDLPSGYGALDQASSEFRYANE
LVEFVRAETGDWFHIEVAAYPEMHPQARSPQDDVQNFARKVKAGANSAITQYFYNADAYF
RFVDDAAKLGATVPVIAGIMPITNYSQLVRFSDMCGTEIPRWIRLKLASYADDTESIRAF
GQEVVAGLCERLLAGGAPGLHFYSLNQAGPTEAIWQHLVK
>A0A7X8V5D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MKITQLFKEKKPLLSFEVFPPKPDYPIETIYRTLGELRDLAPHFISVTYGAGGGNRWRTV
EIASRVKNEEKIEALAHLTCIRHSREEIDEISQRLRQEGIENILALRGDPPADGQAKTDF
TYARDLILHLRRAGEFCIGAAAYPEGRPDNTDLATEIKHMQEKVAAGADFFITQLVFINE
HIYDFLEQLAKKGISCPVFIGVMPVYNTRQIWRITELAGAEIPRELNALLEKYVDSPADA
EKAGIDFAVRQIADLLAHGVDGIHIYTMNRAKQTREILRRLGKSVSELPVR
>A0A7V7AI12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
ATEAEQVLQYYKLKKKVEAGARFIVTQVGYDARKFHEALLFMQLHGLDAPLIGNIYILPF
GVARTMNANRIPGCVVTDKLVAELNEERQAADKGVGGRLLRAAKMYAVLKGMGYRGVHIG
GFNVKYEQVEYVIDKGEELAPNWLDYVKDLDYPMPGGYYYFEKDEKTGLNLEKPVSRKGR
PLDAPVEFVYPLSRFVHNLVFEPDKNLFGLMRGISHKVEGSSLERTYHWFEHINKVLLYD
CKDCGDCALMDLAYVCPMSQCPKNQRNGACEGSYNGWCEVYPNERKCAWVRAYARLKKQQ
EEDNLQAYTVSPCNWDFYQTSSWINFYLGKDHSAKRLGIARPEKKKEEK
>A0A7C6QKE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MENRFKSSLLDKNTVSVTWELVPGRGAKEPQQEFAVQAAEQAAKGGKVHALTITDNPGGN
PAMLADYLGMEVFQKGIEPLVHFTCKDKNRNQMESQLYALDRAGVRNLLVMTGDYPVTGF
KGRPKPVFDLDPVHVLELIEEMNKGLEYPGMKGTIKHQPSDFFAGAAVSPFKATEAEQMV
QYYKLKKKLDAGAKFIITQVGYDARKYHELLLVMKQLGYDHVPVVGNIYVLPFGAAKVMN
ANRIPGCVVTDKLVADIEKEKDAPDKGLEARLLRAAKMYAWMKGLGFAGVHIGGHNVKYE
HVEFIIEKGEELSANWQDLIHEFDYSMPNGFYLFEKDEQTGLNKEVPVDRKNRPLDAPVP
FVYKLSRFMHNLMFEPGKNLFGTMQRIAANAEGTPRAKRLHRFEHANKVWLYDCKDCGDC
ALMDLAYVCPMSQCPKNQRNGACEGSYYGWCEVYPNERKCVWVQAYARLKQYGEEEQLNS
YRVKPCNWDLYQTSSWINFYLGKDHSAERLGIKHPKQKEEKK
>A0A7C6UMP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MFIKDIFTTKKQPVLSFEIFPPKKNSPLETIYTTIEGLKHLNPDFISVTYGAGGSNKDRT
VEITSLIKHKYDIESLAHLTCISSTKDEIKNILTTLKNNKIKNILALRGDLPQDPNFKFP
TPLHYNYAKDLIKQIKQENHFSISAACYPEGHIACNNLAQDIEYLKEKVEAGVDFLITQL
FFDNEHLYDFMDKIRKAGITVPVTAGIMPLLSKNQIKHCLTLSKTTLPPKFTRILEKYGD
KPEVLQEAGIAYATNQIIDLLAWGVDGIHIYSMNRPQTVQRIVENISTFRDLIKK
>A0A6I4YEW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus xianganensis|TrEMBL
MTRVSIELVPRSRSGLRGEIAQVVAALPGVDTVNIPDLTRYSLRSWLGCAFARPAYRAVP
HLRAVDFNPREPLPFLGTLEQHGITEVLVVTGDAPADMSARVYDQDAVDLIRRLRREAPH
LTVYAGLDPYRQSFARERDYLERKLDAGATGFFTQPFFDLRVMDAYSDLIPDGTQVWWGA
TSILTESSLNYWRARNHAVFPRSFTPTLECNRAFAADLLAFARERDQHAYFMPVKVDVQA
YLEGIL
>A0A3D1A4X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MKFTERLKTGKKVYSFEFYPPKTAEDTSKLFNTALELMRLAPDFVSVTNSSSGVAPYRTV
ALCGVLKAQFGLDVVAHLTCLAHTKAEIAEICGGLRKMDITNILALRGDPHNVVSGARRQ
DYSYAAQLVADLKREGGFAIGGACYPEKHPEASSLDADIARLKEKVDAGAEYLITQLFFD
NAYYFRFLEKAAAAGINVPVLPGLMPLTGYKQMQNFTSLMKVGIPDELRRGIERWDGDKE
GMFKFSVDYASAQAEQLLKGGAPGLHLYTLNRSRAAIAILRNVKGEVPE
>A0A2H3DWD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armillaria gallica|TrEMBL
MKISQKIQQSTKEDKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTAEMVKTCQGIIGIETCMHLTCTNMPKEKVDIALREAKKSGCRNVLALRGDPPMGKED
WEAVEGGFVHGIDLVAHIRREYGDYFDVAVAGFPQHQLLPPEERDQELKYLKEKVDAGVS
FIFTQMFYDVEVFVEWVKAVRAAGITIPIVPGIAPIQTWNGFQRATSLAKTIIPQSFLEA
LEPYKNNDEKVREIGTKLVADMCRRILKEDIGIRGLHFYTMNLEKGTKMLLEELNLVPRV
ETIKPLPWRQCLTPSRRKETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDAIKLWGEPKSLEDVTTLFARFCKGTLSALPWSDQAPAIETSVIANQLA
QMNELGFFTINSQPAVDGVRSDDKVFGWGPSNGYVYQKAYLEFFVQPALLSLLLSHIERD
SNITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGQQ
WAKVYDADSPSRKVISDLMDTCFLVNVVHNDFHDPDAIFKPFFRAGAEYKASLLNGNGNA
N
>A0A285NL83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Persephonella hydrogeniphila|TrEMBL
MKISDILQHTKRSVSFEFFPPKTPEGEDSLFRTIKDLEFIKPTFVSVTYGAGGSTRERTI
RIVKKIHTETKLTVMAHQTCIGHTKNEIVDILKEYRNIGVQNVLALRGDIPEGQKESFVF
PPDGCRYANELVSLIRENFGDWFSIGVAAYPEGHPESPDLDTDIFYFKKKVDAGAEFAIT
QMFFDNRYFYNFVEKVQKVGIDIPIIPGIMPVTNFKQIKKFADMCGATIPKELIEKIQPV
ADRPEEVEKIGIEYAVKQCEDLLKHGVKGLHFYTLNKSKATIQIYNQIKDLI
>Q07X90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella frigidimarina (strain NCIMB 400)|TrEMBL
MAFHHAQHAQSLNQSLSELNDINVSFEFFPPSTPAMEEILWNSIRRLEPLNPKFVSVTYG
ANSGVRDRTHSVIERIQKETNLLAAPHLTLVDASDEELVELAKHYWNSGIRDIVALRGDL
PDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDARNAQADLINLKKKIDAGANRAI
TQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVTNFKQTKRFAGMTNVAIPHWLHRQFEG
LDDDPATRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A537AIQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MSTVQCTFSFEFFPPKSDEAAGKLRAAWARLAQVRPHFFSVTYGAGGSTREGTVNTVLEM
HASGLPVAPHISCIGSNEQSIRQLLHAYQQAGIRRLVALRGDLPSGMAAGSRRFRYASDL
VAFVRAETDRWFHIEVAAYPEVHPQSRTAAEDLTNFVLKMRAGADSAITQYFFNPEAYLR
FVQDARRAGIREPIVPGVMPITNFLQLARFSDACGAEIPRWMRRRLEGFGDDRESIRAFG
LDVVASLCERLLAEGAPGLHFYTMNLAEPTLAIWSRLGLPPAA
>A0A1L3FQG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium japonicum|TrEMBL
MTDLTTPARAEGQDGHLQNGHLSSKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFV
SVTYGAGGSTRERTHSTITRILKETTLLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVG
LRGDPAGGIGTPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDT
LKAKVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAG
TSVPDWLAEKFDGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISH
LLGIRAKSAQKAA
>A0A1C4KUD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Termitarium-T10T-6|TrEMBL
MLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKATQE
IAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHPQGV
KYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFFRPE
DYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDPAAV
RSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A536STN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MDLATKEESSTDAASELQRQLRGGRFVVTAELTPPVSSDPAEFIDQALALRGLATAVNVT
DGAGSRAHLSSLAASHFLMRNGIEPILQLTCRDRNRIALQGELLGAAALGIRNVLALRGD
DPKTGDQPDTKAVFDLDTTGLLAMAHRMRSEHRLPSGTEIKGVLKFVLGAAEIPVDPPAG
WRPDGLLSKADAGADFIQTQFCMDAGVVRRYAARLLDLGIAQRLPILIGVAPIPSVRSAR
WMKEKLYGALIPEDIVTRLERAADSKSEGKKICIELMRELAETPGIAGAHVMAPQNHAAL
AEVITDSGVRGRKRPPAKHP
>A0A522W200|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MARNGRVFSFEFFPPKTPEGKDKLRATWQQLARLGPRFFSVTFGAGGSTREGTLETVLEI
RAGGHEAAPHISCVASTRAEIAAQLERYRAHGIRHLVALRGDLPSGVAAAGEFRYANELV
AFIRETTGEWFRIEVACYPEFHPQTRNAADEVRNFKRKIDAGADAAITQYFYNADAYFRF
VDDCRAAGIAVPIVPGIMPIGNFSQLARFSDACGAEIPRWMRIKLESYRDDSASIRAFGL
EVVTALCEKLLAAGAPGLHFYTLNQAALTTAIWQRLAI
>A0A2H3DZM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armillaria gallica|TrEMBL
MKIIDKITAHNGPHPFYFFEFFPPRTDQGFENLLSRISRLSNLRPMAVSITWGAGGSTRD
RSLDLAGLAQTEYNIDTILHLTCTNMMQGMVDDALAAAKSRKIENILALRGDPPRGKEEW
IPIDPRFQRGVDLVSYIRSSPQFSSQFCVGVAAYPDRHPDSLHDEDTEIEYLKAKVDAGA
EFIVTQLFYDVDQFLRWEKKVRAKGISVPIIPGIMPIQTYSSFLRLIKLCGTSVPSFIMS
DLDPIKHDDQLVKDYGVKLAVGMIRRLTSEGKVPGVHFSTLNLEKSVQRVLETLQWAGAA
PPTYNKLIEQDIHDDRSVTPSSASRAAKYGLATISTTDGEAGSGELNNAATWDDFPNGRF
GDFKSPAYGDQDPYGNVGTITLGPWGHPQTINDLTTIFLDHLHSKIPTTPFSPTPLSPES
LTILPHLEELTKRGWWTVGSQPAVDGAPSSDEVFGWGPRAGFVFQKGFVEFFCTEDDLDT
IEKKVADNGKGWVHWFAGNAKGDYRGNIPDDGRNAVTWGVFTGQEIIQTTIIERESFLSW
KDEAFSIWSEWASHYRPGSEERSLLDSVKKERWLVSITHHDYKNTEALWTFLSDVAETTN
M
>A0A536W904|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MQSQKKHPRTFSFEFFPPKTPEGMEKLRATWKQLAQLKPRFFSCTYGAGGSTRDRTLETV
LEIQAAGHRAAPHISCIGATRADIAATLELYKSKGIGHIVALRGDLPSGAASAGELRYAS
DLVAFVRERTGDHFHIEVACYPEFHPQARSPREDLASFKRKIEAGADAAITQYFYNIDSY
FRFVDDCEALGIDLPIVPGIMPIGNFSQLARFSDACGAEIPRWLRLKMQSLGDDVASIRS
LGLDVVTGLCDRLLSAGAPGLHFYTMNQAGLTSTIWQRLGI
>A0A2T5HM93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Celeribacter persicus|TrEMBL
MTKAPKISFEFFPPKDIEACFSLFETLQVLGDMVPEFVSVTYGAGGTTRELTHDAVALLH
RKYGWNVAAHLTCVNATREETLAIAKGYKDAGVNEIVALRGDPPKGQGKFTPAEGGFANS
AELIAALKATGDFKIRVGAYPDPHPDAVDANSDITWLKQKFEAGADSAITQFFFDPNTFF
RFRDRCAKEGITGTIIPGILPITSWKGVQKFAAACGTPVPARYAEEFEASEDHQALAIEL
CTGLCEALIAEGVEDLHFYTLNRPTLTKAVCANLEVI
>A0A1D9P9A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium commune|TrEMBL
MKVTEHLEKAKGKPLFSFEIVPPQKGSNINELYVNIDPLMEFKPPFIDVTTSREEYVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGVDAIPHVLCGGFTKEETEYLLVDCQYLGIDNL
VALRGDPMKGEKYFEPTIGGNHYAVDLVKQIKAMNAGKFLHGELPIQNAPDFCVGVAGYP
EKHIEAPSLEADLKRLKEKVDAGADYIVTQMFFDNQRYFKFVEAARAIGITVPIIPGIKP
VAVKRHLQLLPQVFWLDMPESLISAIENAKDNAAVRQIGVEFAVQQSKELIEFGVPCVHY
YSMGKSDNIHQIASQLF
>A0A1M3HGG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium 50-39|TrEMBL
MKVIEHIQQAKDTLVSFEILPPLKGRTINSIYEHLDPLMAFKPAFINVTYHRSESMFKKK
ADGTFEKVEVRKRPGTVGICAAIMGHYRVDAVPHLICGGFAKRETEDALIDLHFLGIDNV
LVLRGDAAKNESSFEPEPDGHRYAIDLLKQVVCLNHGMYLEEDIKNGGKTNFCIGVAGYP
EKHFEAPNLDTDMMYLKAKVEAGAEYITTQMFFDNQKYFDFVRLCREQGINVPVIPGLKP
ITNRKQLSMLPKVFHVDLPTELSNEILKCKTDEEVEKVGEEWLIHQSRELKKAGVPVLHY
YTLGKPKVIENVVKAVF
>A0A6G4J1G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLYGAVK
RLEKKIESGLSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A074M9I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter longus|TrEMBL
MTSVPSLNQMHEARTALDSPLFSDLPGDIDISFEFFPPKTEKMAQTLQESVATLQPLGPR
FVSVTYGAGGTTRERTHAEVVRVQNETRIPAAAHLTCVNATKDEVNAVARHYWESGIRHI
VALRGDAPDGGAYSPHPGGYANAVELIAGLKQVADFEISVAAYPEVHPDSPDAQTDIDNL
KAKFDAGADRAITQFFFDPECFFRFRDEAAAAGIDAEIVPGVMPVMSFAAVQRMSGLCGT
SIPSWMEGLFDGLDERPAARQLVSATIAAELCRKLYAGGVRQFHFYTLNRAELSYAICHM
LGKRPVGVAT
>S3CHG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiostoma piceae (strain UAMH 11346)|TrEMBL
MDRITDKIAALPPDASYFSLEFFPPKTSMGFANLRDRLDRMARALRPLFVNVTWGAGGST
AQKSLELAEICQRELGLTTCLHLTCTNMSRDLIDKALEDAKVLGIRNILALRGDPPRPAE
YGDAADIAKDSAASGTDLEFTHASDLIRYIRKQHGDYFCIGAATYPEGHAEENHPLGQSL
VHDLPYLVEKVQAGADFLMTQLFFDRAAYEHFETTLVEHPSGAFKDVAIIPGLMPIQNYQ
MIKRTTKLSHARIPDVLMDRLEAVKKDDEQVKSVGVDIISELVEQVKEIKSRTQPNRPRG
FHFYTLNLEKAVSFIIERTNLILPEKEVAVVETDGPTATAEAITVPAIRINEALKLPLAH
HPRRESSIGSDPRNRVIVSGTPSHPDYEATALEASVPAGPVNTRSNTLAISEGEGALGRE
ATWDDFPNGRWGDARSPAYGEIDGYGTSLHMTVNQALKLWGRPSTPEDISLIFTRYLNRE
LPAIPWSEEEVNPETATIKEQLVRLNAKGWWTVASQPAVNGIPSTDAVFGWGPTHGFVFQ
KAFVEFFISSADWAALRKRLSDPAVRDSVCFFAINVGGDFESSDESTVRVSEGDDADGAP
EASTNAVTWGVFPGKEIITPTIIEEVSFRAWSEEAFDIWKEWAALYPKNSVTDKLLEKTR
DDYWLVNIVHHNFIDKDALWSLISS
>A0A1Q5MUS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02488|TrEMBL
MDSLSTATAPALAPLLDDFSLEMTGKDVPNLEAARDRIPAGTRINITFLGSEDLDTRLSA
ARAVRRLGYVPVPHVAARRLRSRPELEELLAALRSDGTADNVLVIGGDPATPHGPYDDSL
ALIRSGLLQSYGVRHVGIGGYPEGHPAIAGPALWSAIEDKTTALARQGLSGDVITQFGFD
ADPVLAWVEAVRKRGIDAPVRVGIPGPAGIKRLMTYATRFGVGTSTSIAKKYGFSLTNLM
GTAGPDRFIRALAEGYDARRHGVLKLHFYTFGGIGATSRWVTEFRAGAGG
>A0A366MWH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter vitoriensis|TrEMBL
MFETLIKKLQEDKYLTLETTPQHEPSMHNIIEKIKKFKINEKVDGFTCTDSPLAKLKYNS
LFAAVKLQQEFNKPAIATMTMRDRNKIALQSDLLGANDFDIRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFGVVNSYAKSFGSLEKKMFLKI
QNGAVGVITQPVFDIENAKKLLESFDIAKEGVEGEKKKAQLIFGLFPITKLRTALFLSAQ
VPGIHVPQFWIDELEKAHNIGEDEEYKIGMKLSRDLFNDINKIHPKIHLMTSNNNFNLAN
ELLS
>A0A414FXA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola plebeius|TrEMBL
MKVIDLIKNSKEPVFSFEILPPLKGNSIQKVYHIIDKLREFDPKYINITSHHSEIVYLPQ
PDGNLKKTTVRKRPGTVAIAAAIQNKYGIQAVPHIICKGFTKEETEYALLDLNFLGINNL
LLLRGDSKPLDIAEKDLCLYHEHATDLQEQVNRFNQGIGLDGSKIEGIETPFSYGMACYP
EKHEEAPNMESDLFYLKEKVRNGVDYVVTQMFFDNEKYYAFVERCRQEGIDVPIIPGVKP
VVFKNQLNVLPKVFRTDIPEAFASELRKCTTDEEVKAVGVEWCKAQCKDLLAHGVPGLHF
YTFMASDSVYKVAKEVY
>A0A373Y8Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF16-40|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYIVSQGNFDIAGACYPEVHGEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>B2FPB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia (strain K279a)|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RTEHGDAFHIEVGAYPETHPQATDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWIGRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLRG
>A0A258HWQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. 32-60-15|TrEMBL
MNASYDQLREARTALDTPLFAGLPGDINVSFEFFPPKTDALMAQLWDVVETLAPLEPHFV
SVTYGAGGSTRDRTHGTVARIIKEAKLPAAAHLTCVDATKAEIREVAESYWEAGVRHIVA
LRGDMGAPGVPFTPHPDGYANAAELVAGLKGIAPFEISVAAYPESHPDSPSHQADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAAACGAA
IPAWMDGLFEGLDTHPGSRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPTRPGLEKAA
>A0A6H2CWR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio sp. zrk46|TrEMBL
MFIPDLINSNDGPFISVEFLPPRREAEWEGFQTAVEKIKAIQPLFAAVTCGAGGSGSLGT
LKASRNLAEEHGFNVMPHVACVHSKLESLKQQLDDIKACGIRNVLAVRGDYPEGVESAPE
GLRYASDLVQRINELAPDLAVGVAAYPDGHPESRSIIEDIEFLKLKLDAGAAFGVTQLFF
DNRRYFDMVDRLAAMGCHKPIIPSVLPVRTLGQIKRVTQLCDAPVPGNTLAAIENAHAKG
GNDAVMELGIQLAADQIADLIKNGAHGVHIYPFNRADMCVDILERAGLM
>A0A2N1U4E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium HGW-Planctomycetes-1|TrEMBL
MSRKQTGIIMTPNKLSELLSRQIVFGDGAMGTMLYAKGVFINTCFEELNLSRPQLVVEIH
DLYISAGSDFIETNTFGANEFKLAKFGLADKTAQINAAAVKIAKQSANRARSESDGKVIL
VAGGIGPLGIDIAQGGRISEKEIISIFTNQINTLAQTGADFLLFETFHNLRELLIAIGCA
VKTCNLEIVAQMTINENNETLYGDKIDFAIAKISQISRVAAVGLNCSIGPAAMLETITLI
KKATAKPISLQPNAGLPQGIDGRTVYMCNPEYMAEYAKRFYENGVKIIGGCCGTTPEHIR
QMVKTVRPLHKADLSAAVIEVKPSPKQAIAQKPVELKDKSKIGEKLASGQKIYSIEISPP
KGTDVSQLIEKVKLCEKYGIDAVNIPDGPRASSRLSAMITAVKIRQSCNIETLLHFCCRD
RNIIAMQSDLLGIQAIDLKNVLIITGDPPKLGEFPDATAVFDLDSIALTKVVSNLNRGID
IAGNSLSVPTSLVIGVGANPAASDLDREIARFRKKVEAGAEFAITQPVFDENSFFKFLEL
TKDCKIPVIAGIWPFTSYKNAEFMANEVPGVVVPQKILEKMSRTKDAKDGRKMGVQIAVE
LMDKIKDNVAGFAISAPFGNVNMALAAAGKIDVSLSF
>A0A5Q0P6Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter wanghuae|TrEMBL
MSQLVTYFAKNQFCVLVEYLCTQKEILPVRHTFAGYPALMTLADRVHADDDLAPILAAKA
YPKDIEKVLHFAGKGRDIADFEQFLKRAKTLGQQNLLLLTGDKLKSHQNGEGILPRTRYL
ESVNAVVAAKQEEGFCIGVAFNPFKYAEAERDAQYLKLHKKIKAGTDYIITQLGYDLSAL
KQAKAFLNEHAYTQKILACVMPLTFGRANFMLKQQVAGIVITPHIFNLLQEEKAAGLTDR
VYERCALQILICQHLGFAGIHLSACHQPEEQMRLEGYIEQYRHLNLSELEQRWNTLWQVK
TGQEFYPELTSYSRLASKRDILKYQHLHLMHDVIFDSRVGKGVGRFIFQSKFWQGKAAAQ
ALLKTEFISKHAVLGCESCGQCRLGDTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVHQTDILKKKLIPTVPIDVRGTSSWKNWYTDAVG
>A0A7W2EBV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium haemomassiliense|TrEMBL
MFEASPSTRLSASAPLDREGAPLIRRPRPKRQRTALSFEIIPPRPTDDAEKIEQLIAGLA
EYKPDYVSVTSSRRSEWLEGTAAVISRIAETTDLRPIAHLACTAGTRDEMAEWVRVLIDA
GVRGFLALRGDLPETGLPADHLQHATDLLNLIQDVQEEEAFRLAAGKLALSVACYPKGHA
ESRNFDHDLDVLLAKQRLGADFAITQLFFEAQDFLEFVEVARLAGVRIPLIPGIMPMTSL
KRVRRMGELSGLEVPVGVEKQLLEADDEYEAGMQLTANLAREILDAGAGGLHVYTHNNLD
VTRDFLDRIGIDKGQQ
>A0A179D583|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosulfurimonas dismutans|TrEMBL
MEPRSHLQKVLSEGHFAVTAEIGPPKSADGEVVRKKARILKGYVDAANITDCQTAIVRMS
SIASAVLVMAEGVEPVIQMTCRDRNRIGIQADLLGAAALGVKNLLCITGDHQKFGNHPEA
KGVFDLDSIQLTAMVRQMRDEGKFLCGEELTGARPEFFIGAVENPFADPFEFRVKRLEKK
VKAGAEFIQTQIIYNVERFKKFMEMARDLGLTEKVYILAGITPPKSFGMARYMKYFVPGL
DVPDEILKRMKEAKDKREEGINIAVDIIQQVREIPGVAGVHIMAIEWEEAVPEIVKRAGL
HPRPLEAEVKPAIAVEVERPEKIEVVAPPKEEEEVAEGPPKIEIPVEAVKEVFSSVRSSI
ESLREGINLLHDSLARLERALLGGEVVPAEVPQVEVKVEEKPVVEEKPAEEEKPAVEEKP
VEEIKKEVKPEEEKPEEKPTEEEPEAKPIAEEPKAAEPKPEEKPAVEEKPAAPAGPPPEG
VELGGFIGEYRPLSERAAGLPEDLYKDPGTAFIREVEIGKGEKAFKVGGTNVLPFQLFEG
EMKNQPRIAMEVLDVKPENWPESLAKYFEDVFDDPAAWAKKCVETYGAEAVCVYLMGTDP
NYLDLDAKHAREVVEKVVKAVDVPIVVWGAGHAEKDVEVLREVAEILGDRGAVIGPVEEA
NHRTLGATAMGYGLPVVATSPIDVNLAKQLNILLENIGVSLDKILMDPSIGALGYGLEYT
YSVMERIRLAALYAQDEKLQVPFVCNVGREVWKTKEVGLPTDEILGDQEVRGVLMEAITS
VALALAGGDLFIMRHPKAIELTKTIISALMQEN
>A0A7X0GKY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. AK010|TrEMBL
MALGTASIRSDHARTVRDMLAGGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWDADVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLERIGSLTNAAF
PPALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSPQA
>A0A3F2UDU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. YM1C-6-2|TrEMBL
MNEPNFSRRPDIGQKIAVSFEFFPPRTDDMETRLWDTVQRLEPLAPRFVSVTYGAGGSTR
ERTARTVNRILTGSKLTPAAHLTCVDATRGDIDTVIAEFAGMGVKRFVALRGDPAAGVGA
RYQPHPGGYANGAELVSALKAQGDFDISVSAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGVLPIHNFTQVANFSGRCGAHIPAWLGERFD
GLQADPQTHALVAAAVAAEQVMDLVERGVSDFHFYTMNRADLVVAVCHMIGIRAHSAGVP
ASAAA
>A0A2V6MIX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHISDIIREDSPTFSFEFFPPRTPDAAEILYHTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIEAILLRYAKSAIGNILALGGDRPRGIEYDKSR
DSFQHAIDLVKFIRRFNEAGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVGAGA
DYIVTQLFFDNRDFYDFRERCALADIHIPIIAGIMPITSMSGFKRIAELAGGARFPARLL
RALQRCENDPEMVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRIIFDSLGIPRRR
NAQAQTV
>A0A4P5ZDN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MPIQFIRDLHAARRAAGRPVISFEFFPPKTDEGEKNLLEKTLPALLEIQPDYCSVTYGAG
GGTREKTLGIVDRIQREHGLTAMSHLTCVNATREEIHSVVEQARALGIKNILALRGDPPG
GSGEWKKTEGGFEYSYQLVSYLRELGGFSIGTAGFPEGHIACTEGREVDWRRLKAKIDCG
ADFVITQLFFDNDDYFRFRDFLAKLGNQAPIFPGIIPILSAGQIKKFTALCGAAIPAKLS
ARLDALAHDDAAAVEFGIEYATEQCAGLLRGGAPGLHLYTLNKAHSTVRVVKNLNLH
>A0A3C1C374|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MTSPTIRELLEARRQPTLSLEFYPPKDPLGFGILGGSIERMRPVRPDFVTCTYGAGGSSR
EFSFAAWELLGRMGFAPVVAHLTCVGASRADLAAQIDRIHAAGIRNIMALRGDPPRGETE
FKPVPDGLAHASDLVALIKSRRPDICCGVAGYPETHPEAPSLADDLRHLKEKLDAGADFV
NTQLFFDNAAYFRFLDAARAAGIRAPILPGLMPVASLAQLDRALAFSRATAPQKLRDALQ
APDPEAARRAGIDWLVAQIDGLIAHGAPGIHLYILNQAKTILDPRLAQCLARWHTASS
>A0A6B2ICA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. SE1|TrEMBL
MAFHHAQHAHSLNQSLSELNGDINVSFEFFPPSTPEMETLLWNSIQRLEPLNPKFVSVTY
GANSGVRDRTHSVIERIQQETELVAAPHLTLVDASDEELLQLARHYWNSGIRNIVALRGD
LPEGSPKPTRFASDLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIEAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVGNFNQLKRFAAMTNVSLPGWLHRQFE
GLDNDPGTRALVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A0J7IPP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. FH2|TrEMBL
MKITDHIKNANGKALFSLEVVPPKKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTQGGHASAMDLVHQINDLGRGKYLHNEEKECEEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVTKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVESAKNNEAVKQIGIEWAINQCKELLDFGVPVL
HFYSMGKSDNIKQVAGELF
>A0A0R2HG15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kandleria vitulina DSM 20405|TrEMBL
MKIIDCLNQGKVTLSFEVFPNKYSKNFEAVANKAKEIARLHPEFMSVTYGAGGGTSQYTV
NIAKEIQEKEGVDVLAHLTCVSSTKEKVHEMLESFEANGIKNIMALRGDLPETEVPHDYE
HASELIKEIKEYNPEFCIGGACYPEGHPEAKNKDEDIYYLKKKVEAGCDFLTTQMFFDNS
IFYNFLYRAREAGIEVPIVAGIMPITRKEQVKRAIQLSGSSVPSRFFSMVDTFGDNEKAM
KQAGIIYASEQIIDLIANGVKHIHVYTMNNPDVAEGIMNNVSEILK
>A0A4P5NSU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataeibacter diospyri|TrEMBL
MTDGLSNWLSERRIDGLLSRNSETPILSFEFVPPRTDAMEQRLWCCIRHLAPLAPRFVSV
TYGAGGTTQAGTLSTVLRLKRETDLIPAAHLTCVGATREEVDGLARCYRDAGVNHIVALR
GDPPAGAADYSPRPGGYAYASDLVAGLRRIADFDISVAAYPETHPTASSPDADLDNLKRK
LDAGATRAITQYFFDNEIYLRFLDRCLAAGITAPIIPGIMPVSNYEQIVRFSAVCGVTVP
AWLRHLFDGTAENPELRRIVASLVAVEQIRTLQTYGLNEFHVSTLNRSDLIYAIAHILGV
PPTQTNASRNVTDLLETTEVPDDRETPENFDPTKGTQEGAPPFMLRTLFG
>A0A522AN89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
FIREQGDFSIGVAGFPEGHIACTAGKQVDWRHLKEKIDAGADYVLTQLFFDNADYFEFRD
QLTQQLGVSVPLVPGIASTFLSAGQIQRFTAKCGARLPASLNARLDQIGEDDVAATEFGI
EYATQQCAELLRAGAPGFHFYTLNKSSPTVRVLKNLGLAK
>N8UDB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 102129|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLHIVHQELQRLNPEFFSITYGAGGSTRERTLATIHDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGNHFHIEVAAYPEMHPQADSFDADIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERLEKEGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A8J7UZ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niameybacter sp|TrEMBL
MKISTLFNESKPIISFEIFPPKQTTSIESIYSTIDALAPLSPDFISVTYGAGGSTQGKTV
QIASLLKNQYNITPLAHLTCVGGSKESMDQILDELEREGVHNILALRGDLPEGSSLGDFS
YASDLIKYIKQRDSFDVAAACYPEKHIEALTLEEDIKHLQYKVDCGAELLISQLFFDNDA
FYKWRENVRSQGIHTPIVAGIMPITSGKQLERMVTLCGASIPASIQNLIKAYNHNAQALK
EAGIAYATMQIIDLLASGVDGIHLYTMNQADIAKRIMENIRGINYAVRTKRA
>A0A2K8U454|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thiodictyon syntrophicum|TrEMBL
MNATDQHRPAFSFELFPPKTPEGSAKLKTVIAELAAVAPEFFSVTSGAGGSTRAGTFETV
AWLRRQGLDTAPHLACIGSNPDEVRALLAGYGAQGIHRIVALRGDLPSGTGTGSAGAFRY
ANELVEFIRAEHAADFHIEVAAYPEYHPQAPNPARDLENFKRKVQAGADSAITQYFYNAD
AYFGFVDAARTLGVEIPIVPGIMPITNYTQLARFSDACGAEIPRWARRRLEGYGDDLESL
RAFGHEVVLRLCRNLLDGGAPGLHFYTMNQSGPTLRLWADLGLST
>A0A2S7JYL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. TS-CS-82|TrEMBL
MNANNSLSIEFFPPKTPEGAEKLRAVRQALYPLKPQFCSVTYGAGGSTQAGTISTLKEIL
SEGMAAASHFSCIGATRDSVRQQLAEFKAMGVKRLVALRGDLPSGYGAGGEFQYASDLVA
FIRAETGDDFSIEVAAYPEIHPQAKSAEADLQAFATKVKAGADSAITQYFYNSDAYFRFV
EDADKLGVHIPIVPGIMPISSSSQLLRFSDACGAEIPRWIRLRLQGYGDDIASIKAFGLE
VVTDLCDQLRAGGAPGLHFYSMNQSATTLAICKNLGLSA
>A0A268TCP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. 11S03491-1|TrEMBL
MLSMEFIPKQKDQDFEMIAKWLDKIHLDFIIIPDSPNLKSTPEASIVALIFEKKLGIQFI
PSIAGSGRREERIESLLLGLKYSNIFNVAVVGGDCSGMGEIDGVGLAKKAKNILGEESLI
ICGSKGTIDLANKKNLEAKISNGANLIITQPIFHPKTAQKFLKDFEDVAKGSKVEAMIGF
FPIYEERFCIQIRENNLGFDIPLGYQKDIAKNPFESNLKLYEEMKAICPHIHISGAKNNF
LNNFISFLPSSKDF
>A0A0Q8HST5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Root68|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKAKAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A380IJU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus agalactiae|TrEMBL
MSKFLEKLKTDILVADGAMGTLLYTYGLDTCHESYNVTHPEKVLAIHQAYIEAGADVIQT
NTYGAQRHRLKNYGLEDQVVSINQAAVNLAHQATLGKETFILGTVGGFRSQRQCDLTLDN
IVEETLEQVEALLATGQLDGLLFETYYDIEEITTVLKIVREMTDLPIITNISLHEAGVTS
NGKPIVEALSQLVMLGADVIGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASQLSLDGE
NSQYQFSQNSEYFGKSAELLVAEGVRLIGGCCGTTPDHIRAVKRSIRGLKPIERKVVTPI
IPVKDFVRRIRRTDTLVDKVKKEVTVIAELDPPKHLDIVQFQKAIRAIDQKGIAAITLAD
NSLSNTRICNLSIASLLKDEISTPFLLHIACRDHNLIGLQSRLLGMELLGFNHILAITGD
PTKLGDFPGATSVYDVTSFKLLSLIKQLNQGLSYSGASLRRPTDFTVAAAFNPNVKNLTR
TVKLIEKKVASGADYFMTQPIFDHSVLKELADLTKTVEQPFFIGIMPITSYNNAVFLHNE
VPGIKLSESFLSALEKVKDDKEACLTLALNESKSLIDEALNHFNGIYLITPFLRYDLTLE
LIDYIQKKQVRKPS
>A0A6L8A0B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MADNRGRRQGRPGRRRRISGMAEKTMNGPVSANGLKSGGKLERVLAAGGFAVTCETSPTA
TTDLAPLLERVAPLKGVADAVNVTDGATAKAHVSSLVLAGAMMRQGIQPVLQFTVRDRNL
IALQGDLLGAGALGIPNILCLTGDDPKKGEEPDASPVFDLDSAGLMRLARRMRDDGLLNA
GREIKGPPKLFIGCADAPMAPKPGWEPKSLRAKIDAGADFAQTQYCFDLETAKTYFTRLA
DFGITEKLAFLVGIGPLASLRQAKWMDENLFGVSIPDAILKRLEGADDERAEGKKICAEL
IQQLREVPGVRGVHLMAPRQEAAMAEVIERSGVLEGRPALSA
>A0A2E5P8A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MADSKSIFDHTPKLPSTRLGEGVCASALRDISVSFEFFPPTSNKIAEQLWNAILRLAPLD
PNFVSVTYGAGGTTRERTFDTVERIMHDTVLTPAAHLTCVGDSRGHVDDAARRYWDAGVR
HVVALRGDPPQSAEKFEPVKDGYTHASDLVAGLKRVANFEISVAAYPEIHPEAANAEADL
DNLKRKLDAGAGRAITQFFFDVDLFLRFRDRARAAGIEAPISPGILPVTNYARLVSFSAR
CGTSLPDWLSRLFDGLDEDPDTRRLIAGWIAIEQCRQLTIHGVKDIHFYTLNRAELTRAI
CHALGIRDTSTTAEATS
>C2T609|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus BDRD-Cer4|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A357G0J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MKSTFSFEYFPPKTPESEGAFWEASRELAALGPRYMTVTYGAGGSTRDKTLEICTRMAAE
NPSIPIASHLTFLSTTKADLEKYVDALWQNGVRNIVALRGDLPKGKTFDDYKGGDYFTYT
SEFVSWLKARHPFDISVGAYPEKHPDAASLDADIEALRLKCEAGADRAITQFFFNNDSYF
DFVERCSAKGITTPIYPGLVPIYDFAGLQRFAKNCQAHLPDWLHGKFEGTQDKPAEAHKI
AEDLLLKQVDDLTANGVKHIHFYTLNKAGLTAKACRSMAKVYA
>A0A2E9E6K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MGSITQTTTTAPAKKTLEELLKAETFVVTAETSPPVSIEGDLVLEKIAPLAGYADAINIT
DGAGAKSHMASLVTANFLIQAGLEPILQMTVRDRNRLALQNDLLGAGALGVQNILCLTGD
HVSTGDQPNAKMVMDLDSCSLMELAHNMRDKSTLANGRPITGTTPKFLIGAADAPRDPAD
GWSPEAVRAKIMAGASFFQTQFCFDIDLVKKYIQRLRSEGFLEQAKFLIGIGPIPSAKSA
IWMNENLYGVEIPENIIKRIDSSEDQRAEGKKICAEILGQLSEINGVGGAHLMGPNSEQA
VAEVIQASSILDSRAIA
>N2B3Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium plexicaudatum ASF492|TrEMBL
MHLTCLCYDRTEIDQFSKELAAEGIQNVLALRGDRNPDIPEKKDFAHASDLITYLKQTSD
FCIAGACYPECHPESEGRVEELRHLRQKVDAGAQVLLSQLFFDNNYFYRFVEDCRIAGID
VPVTPGIMPVINASQIKRMVTMCGASLPQRFERIIHKFEGNKQALFDAGMSYALSQIIDL
LANDVDGIHLYTMNNPTVARKICEGIKHIV
>A0A0F4ZED8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thielaviopsis punctulata|TrEMBL
MDKITDKIAALPADANYFSLEFFPPKTDMGFSNLRNRLDRMERALHPLFVNVTWGAGGST
AQKSLQLAETCQRELGLTTCLHLTCTNMSRRLIDKALEDAKVLGIRNILALRGDPPRKAE
YADSEESSEDIDEEYCYAVDLVRHIRKNHGDYFCIGVAAYPEGHADGSHPTGQTFEHDLP
WLVEKVQAGADFIMTQLFFDVSAYEHFEKTLRNHPSGAFATIPIIPGLMPIQSYQMIKRT
TKLSHAKVPESLMARLDAVKGDDEQVKSVGVDILSEIIERIKGLKTPASAGPRGFHFYTL
NLEKAVSLILEKTGLIPDKDAQDEEEAIIDDDIRGSSLRLAVNGSALSAATPAVSTVQAP
ARRLSSLGSDPRNRVIVSGGSVGNSDYVVTAQDATFLSKPINTRANTLAASEGEGVLGRE
VTWDDFPNGRWGDARSPAYGEIDGYGVSLHMTPAQALQHWGYPVTTEDINALFLRHIRGD
LAALPWSEEELRPESSAIQTHLEALDARGWWTVASQPAVNGVKSTDATFGWGPANGFVFQ
KAFVEFFVPRTAWTALREKLTRPDVKDHVCWYASNAAGDFTSSDRLAALAAEAPTPAAAT
ENSSSGPQEPSTNAVTWGVFPGKEIVTPTIIEEVSFCAWSEEAFGIWGEWARVYPAGTAS
ARLLEGIRREYYLVNVIHHDFVDKEALWELLLKE
>A0A2G2R5E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSTTSRSVVSELPIASPLPRDAEVSFEFFPPKTDKMDAKLWDCVERLAPLKPKYVSVTYG
AGGSTRERTHATVTRIRDETDIAPAAHLTCVGATREEIDDIARDYWAHGIKHIVALRGDP
MDGIETDYVPHPGGYAYAEDLVKGLKKIADFEISVAGYPEKHPQAQSLDADIEFLKRKVD
AGADRVITQSFFDNDKFLQFVDKARAAGITVPIVPGILPVTNFKRVQEFSTQTGTSVPRW
MAEIFEGLDDDMETRKLVAATVVAEQCRVLYANGIKQFHFYTLNRADLTYAICHILGVRP
>A0A2E2YCI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MKVTKQDIASLLSGFSIEVTPASAQNIDSFANHLPLNTSINVTFLPGSNIDDTVNVSYRL
HQEGFKPVPHLAARNFVNQKSLEQCLEQLTTIANVEEVLVIGGGLNAALGPYHSTLQILD
SGLLEKYSIKKVGVAGHPEGSPDIPDLELAQALQDKNSWARNSDVKVYIATQFCFDASKI
IDWENRINKSGNTLPIHIGLPGLASLKTLLKFAQMSGIGPSMRVLTRQTKNLAKLVMTQE
PDIVVSELASHVTSNPDSLINQVHFYPFGGLGKTASWVNSVIKGEITLKSNKGFSINNKN
>B8KLD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium NOR5-3|TrEMBL
MSKSAAISFEYFPAKTDAGREKLLNVTTPELQAIGPEFFSVTYGAGGSTRDNTRGIVEGL
NAQGLSVAPHLSFGLDDEATIGALLEDYKAAGINRLVALRGDLPSGAGGGARLVYANELV
AFIRERTGDHFHIEVAAYPEIHPQAESYESDIQYLKGKFDAGADSAITQYFYNVEAYFYF
LDRCAALGIDKPIYAGIMPITNYANLARFSKNCGAEIPRWISKRLEGFADDQDSIRAFGI
DVVTQLCQTLLESGAPGIHFYTMNQTQPTLQICRNLGL
>A0A1V4W8C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdus sp. PtaB.Bin027|TrEMBL
MSTQSNLERVLKSGTFAVTSECGPPRGADPEVVKKKGSYLLGYVDCVNVTDNQTSVVRMS
SFSACLVLKGVGLDPIMQMVCRDRNRIAMQSDILGAAALGINNLLCLSGDHQKFGDHPTA
KNVFDIDSIQLIQTVKGMRDEGRFISGQEVKGKPNIFIGCVENPFADPFEIRALRLAKKA
AAGAQFVQTQCVFNVEKFEKWMEMVRDLGIHEKIHILAGITPMKSIGMAQYMKNSVPGMD
VPEEQIERLKGVPKEKVTEEGIKIAVETIERVRAIKGVAGVHIMAIEWEEKVQEIVKAAG
LHPRP
>A0A4R5YNK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria rosea|TrEMBL
MTPRPTARPAPPSLSYELYPPRSAASADTLLRTIEELEPTRPDHVSVTYSGDEQRRDSSL
ALLDHLLARTSLRPLAHLTCVGSTRAELEQTVAALVRRGVRGVLALRGDLDPGAEPGELR
HAGELVELVREVEQRHTAALAAGRLAVGVAAYPTRHPESPSFRHDVEVLLAKQRSGADFA
ITQVYFRPQRYERLVAAARAAGVTIPIVPGIMPVTDPRRLRTLCRLAGLAPHPGLAAALE
DAPGPAERHRAGVAFAARLARAALDAGAPGLHLYTFNEHRAALDLLEHVDLPRVPHVPVA
LDDLLLPA
>Q9X7G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum extorquens|TrEMBL
MWFRNARKKLSPTHDSATDSTDALRSSVSLLARDLSLEVSPREALRGAEGLETLAPGTRV
FITRLPKGSFEETLAASTRLRELGLRPVPHITARTTSDAATFAKQLGRYVGEAGVREILL
VAGSNEKAEGAFSNTLQILESGVIESSGLTALNVAGHPEGHPQADERELHRALEVKNAFS
TRTGIPLTIVTQFFFDPAPIIAWEARIREKGNRLPIDIGLHGVTGVASLAKHAVACGVGA
SIKVLGSHSGSVLQFAQIRTPDRLLSGLAAAKARDPANLFRNIHVFPLGGFKRTVEWANA
VRNGRYSFASDGQLEVATSD
>A0A2A4P880|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MNRNAPLAIASPLPNDVRVSFEFFPPNTEKANETLWNSIQRLSPLKPSYVSVTYGAGGST
RERTHATVYRLRHETDLEPAAHLTCVGATTDXIDDIARSYWDAGVKHIVALRGDPAEGGG
PYQPHPGGYAYASDLVAGLKNIADFNISVAAYPETHPEATGAEADLDNLKRKIDAGASEA
ITQFFFDTDVYLKXLERARAAGITVPIIPGILPVTNFTRVAEFSDKCGTKVPHWMADLFD
GLDDDPQTRKLVAAGVAAEQCRALHXEGITDFHFYTMNRADLVYAICHILGVREKREA
>A0A2N6TK10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium aurimucosum|TrEMBL
MSPRLSASAPLDQISEDTPRELKRTALSFEVIPPRHDADAAKIDRLLATLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTGEELVGWIDTLVDAGVRGLLALR
GDLPEGGMPEGHLPHADSLVRLIRRWESDRVARLAAGRLAVGVACYPNGHAESATPDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTKVLDQLAAATSPEEEKEIGMQITASLAKSVMNAGADGLHIYTHNNPDITTDLL
NRIGVIP
>A0A2E9WU51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSRAANLEEPGTGFKSDSHLERVLAGGHFVVTGEIGPPKSWDAEVIRQKAKLLKGYVDGA
NITDNQTAIVRMSSIAAGIIVKQEGLEPVIQMTCRDRNRLAMQSDLLGAAAHGINNVLCL
SGDHQSFGNHPGAKNVHDIDSLQLVQMVKGLREGHFQCDEEIKGGGPGYFIGAAANPFAE
PLEWRPFRLAKKTAAGADFIQTQLVYDIPRFREYMKKVVELGVHERTAILAGVGPLKSTG
MAKYMRDRVPGMSVPQECIERMAGAVAGIDEGDKKARAEAWRAEGIQLCIEQIQEIRQIE
GVAGVHITAIEWEAAIKPLVEGAGLSPRPPMRDG
>A0A2T3L6J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium indicum|TrEMBL
MGYSHASHLDSLNQNIADINGDINVSFEFFPPSSEKMEETLWHSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLIAAPHLTCIDASRDELRTIARDYWRNGIRDIVALRGD
LPAQGTKPDMYAADLVELLRKEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNMTQAKRFAAANNVKIPGWLEKQYQ
GLDDDLLSRQMLGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAEVEAK
>A0A3D3LKV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MTSISLEFFPPKSAETEAKLWDVINELAVIRPDFVSITYGAGGSTRNRTHKCVKHLVTKT
DLKPAAHLTCVAASKSEVDEVIEDYALAGVKHIVALRGDMPDMEAFSPHPDGYRGSVELV
DALSRRGGFDVTVSAYPEKHPESGDMQTDIDLLKAKIDAGATRAITQFVFDTEHHYRFRD
VLADNQINIPVIPGIMPTTNFKGVLRMSEACGASVPDWMKSKFEGLDDDLESRRALAIEV
ATEQCRDLIKSGFENLHFYTLNQATVTQAVCKALSLENVGVQ
>A0A345J872|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malaciobacter mytili LMG 24559|TrEMBL
MFEILIQKLQEDKYLTLETTPQHEPTMHNIIEKIKKFDLQNRVDGFSTTDNPLAKLKYNA
LFASIRLQQEFKKPVIATMSMRDRNKISLQSDLLGANEFDVRAILALTGDPAKMSDQPHT
KGVFESNSSMLLKMIKSFNYGMDMAGRPFKIEPKQIYPFAVSNSYAKNFSSLQKKMHNKI
QNGAVGIITQPVFDIDNAKKLLETFELAKEEVTGNKKKAQLIFGVFPITKLRTALFLSAQ
VPGIHVPQEWIDKLEAANQISEEEEYKVGMQLSKNIFDELRRLHPKIHLMTANRFDLADE
ILD
>A0A2D8DA68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceicoccus sp|TrEMBL
MNDTVSTIGRPLFASLPGDIDVSFEFFPPKTEKSEQHLWETVLALAPLRPDFVSVTYGAG
GSTRDRTHDIVARIIREVGLPTAAHLTCVEASKDEIREVAEAYWEAGVRHIVALRGDPPT
MGQKFVPHPDGYASAADLVAGLKDIAPFDISVAAYPETHPEAASAESDLDNLKRKLDAGA
SRAITQFFFAPEKFLRFRDLAAAQGIDAPILPGILPVSNVAQTRKFAKACGAEIPKWMEE
LFEGLDNRPESRKLVAATIAAEMCRSLYAEGVRDFHFYTLNRAELSYAVCHLLGMRPKES
ARNASGLQETAA
>A0A3P6JZE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium carnis|TrEMBL
MIYEYLKNRALVSDGAMGTYYSEISGNDISYCEFANLNDKNTIKKIHSKYIEAGAKLIRT
NTFSANIYDLSVTHKALKEIIHSGIDIAKEATYNKDIFIGGSIGPIRKENSLDEFDEEIL
DEYKFIVDCFLEKKIDIFIFETFSNYTYLDEISKYIKEKNNETFILTSFAFKPDGFTRDG
LSVSKVLSYLENINEIDGYGFNCGSGPSHLCEIVKKSAINNKIIAVLPNAGFPEIIHERT
VYPNNPVYFAKKVSELKNFGVSIFGGCCGTNPSYVKELSSYISASKLGDNIKTNVVITNE
HTIKLKKNKFKQKLDDGEFVITIELSPPSDTEISKVIEGARLCKENNVDLVTVPDSPMSR
VRADSVIMASKIQREIGIDAMPHICCRDKNTNAIRSSLIGSHIENIRNVLAITGDPVSDA
SKVQTKSVFNLNSFKLIELINDMNTEVFKEDGMLIGGALNLNVFNKEVEFNRMMKKIEKG
ADFFLTQPIYDDEAIEFLKVIKQRVDVKILAGVLPIVSYRNAMFLHNELPGVTIPEKYIN
MFSEDMTKEEGQSVGTEIAVDIVKKLKEVSDGLYFIAPFHRVSMLIDIIKQIRD
>A0A3E2VG50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium innocuum|TrEMBL
MIEEYLNTQGYMLFDGAFGTYYAQRYAEEQEPCEMANLKHPQRVAAIHREYIEAGADAIK
TNTFSANEQQLECSWEMIQQILQEGYRIAKETAGDRVKVFADIGPIMEQKNVSLAQQYQR
IADVFLAEGAECFLFETLLNTRELHAVSAYIKQRCPSACIIVSFAVTADGYSRQGIAMHQ
LLQDCLTDEHVDACGLNCVCGPMHMKRLLDSIDRSKKPILIMPNAGYPTILANRTYFRDS
STYFAKEMQEIWKKGARLLGGCCGTTPVYIQKTKEALQEQTIVQKTLQPAQQTDKIVRED
HNPLRKKLQKRQQIIAVEFDPPANCEIERFMNNAEFLKEAGVDAVTIADCPIARARVDSS
LMACKLHRELGLEVIPHMTCRDRNINATKALLFGLQIEGIRNVLVVTGDPIPSEDRQEIK
GVFNFNSQLLAGYIRDLNETMFREPFLIFGALNLNAVNFEAELAKAKRKVAQGMEGFLTQ
PVHSRQALINLKRAREELQAYLLGGVLPIVSHRNAVYMNNEISGIEVDDEIIDLYEGTTR
AEAQKLAVAISCKTMDEMRPYIDGYYLITPFHRVEIIADLMKHIHKQ
>A0A8C1LKV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGKDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIITQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKVMRSRCGLNSGTSTT
TTSSSTWWTTTSRSTAACGR
>A0A8C1RJF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADAGWQSSKSDSSGVSNSGESSKESSRXYGCVPGGNESFLFLCVRFDRMGSGGPL
FIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLG
LKNIMALRGDPIGEDWVEEDGGFNYATDLVKHIRCECDDYFDICVAGYPTGHPEAESYDE
DLRHLKEKVDAGAHFIVTQLFFRAETFLKFVKDCRAIGITCPILPGIFPIQGYHSLRQLV
KLSKLEVPEEIMQVIEPIKDNDAAIRSYGIQQAVEMCKVLLASGEVPGLHFYTLNREVAT
IEVLRQLGLWAEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRW
GNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITGQTNPSGHK
VMCLPWNDDPLAPETNLLKDELEKVNCRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQ
KAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREI
IQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLD
SCLWQVIEDMFTLLDSPPETQEEGSQS
>A0A7X7KRA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MKAAGKPVLMALSGKGSDTQRVRATLAAARGKGIHNLLVMTGDRSDRHPLRHGSGRPLPY
EAGYLESLDILRLARQTGGFLTGAVVNPFKYTLADTYLQYFKMVRKLASGADFIVTHAGW
DMKKLQELQWFLARREMHPNVIARLLLLSLDDIRRLDRTVFPGVHVPLEFTALLQRESDI
SATQSLAAQLPRLGLQAAGCRLLGYSGVQIAGVRDQGTLDMVVGRIQEYLQTITTYDAWL
AAWRDYHGDLSFEPVSGAYYAFHGLMTEGASSYGAVTPRPGSMDFEAPRLADRLRSRVLP
WVLEKPSPEWLSTLYRAVCRGGDAVSSSRLRACFFLDRRGCPKRLVYGPCGGSTPEGDCE
FGHAPCFFHRVLSVAAARRELDRLEEAVADD
>A0A3R8QXZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter algicola|TrEMBL
MKVTEHIEQAKGKTLFSFELIPPVKGRSIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
KGGLLEKKVTRMRPGTVGICSSIQHKYHVDTVPHLLCGGFTKEETEYVLVDCHYLGIDNV
MALRGDSMKEEKYFTPTEGGHCYAKELVTQIRNLSHGEYLHETITSDDYPDFCIGVAGYP
EKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVEAAKNLGIDVPIIPGIKP
VAVKRHLQLLPQVFRIDIPQDLIEAIENCKNNREVREVGIEWAIEQSKELKAAGVPVLHY
YSMGKSDNIKAIAKEVF
>A0A1J3IXZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noccaea caerulescens|TrEMBL
MKVVDKIKSVIEEGKTAFSFEFFPPKTEEGVENLFERIDRLVSYGPTFCDITWGAGGTTA
DLTLDIASEMQNVICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFDCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFLNDCRQTGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAFGIHFATEMCKKILAHGITTLHLYTLNVDKSATAILMNL
GLIDESKIYRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKAWNDFPQGRWGDSRSA
SYGTLSDYQFMRKRSRDKKLQQEWVVPLKSIQDVQEKFKELCLGSLKSSPWSELNGLQPE
TKIINEQLGKINSNGFWTINSQPSVNAANSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TLVEKSKAFPSITYMAANKAEKWISNMSQSDVNAVTWGVFPAKEILQPTTVDPASFKIWK
EEAFEIWSRGWANLYPEDDPSRKLLEEVKNSYYLVSLVDNDYINGDIFSVFA
>A0A2N8H748|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FW305-BF6|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A2A2GUR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. TUL|TrEMBL
MIEQFVAKLGTKQRLLTLEVTPPLSPTLAGSKEVEKLLTLSSEVAIDAFVCTDSPLAHFK
PSSILSSIKLQNLTHKPVVCTLGMRDRNSIALCGDILAANEFGLRSFLCLTGDPIKLGDC
AESKGVFEENSLKLMRIIHNLNEGKVLNGKALKDSIEPIYGFQVINSYANNPQSLKTKMR
KKISQGKPYALFTQPVYSKEMAEFLLQSLDEINAELGTHTTLIFGFFPVVNYKVAIFLRD
KLPGVFIPDTWITQLQNAKDNEYEVGLELSRELLTQLRSLHDKIHFMSANKLELVREFYL
S
>A0A1M5PH19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella jejuensis|TrEMBL
MKVTEHIKNANGNTQFSFEILPPLKGQNIQSIFDNIDPLMEFNPPFIDVTYHREEYTFKD
VGNGLLKKQVVKKRPGTVGICAAIQNKYGVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKTETYFTPEKEGHSYASELVSQISELNNAIYLDEELKNTSPTNFCIGVSGY
PEKHMEAPSLDSDIHFLKKKIKNGAEYIVTQMFFDNKKYFEFVDKCRKAGIEVPIIPGLK
PIATKKQLNLIPHRFYVDLPEELVIEIVKCKDNEQVREVGIEWCIAQSKELQEAGIPVLH
YYSMGRSSNIKKVASAIF
>A0A4U0ZYX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus sp. IMCC35007|TrEMBL
MKTESNLEKVLAAGHLAVTSECGPPRGCKPEEVVAKSKFLDGIVDAVNVTDNQTAMVRMS
SLAASVIVKQQGLHPLFQVTCRDRNRLAMQADIIGAYSLGIDTMLCLSGDHTKFGDHPQA
MNVHDIDSIQLIQMVKDMRDKGIFQGGAELKGSPKMFIGAAANPFADPFELRVMRLAKKI
AAGADFIQTQCIFNVPKFEQWMEGVRKMGLHKKCYILAGVTPCKSLGAAKYMANRVPGMD
VPKDVVDRMASVPKEKQADEGVAICVETIERLKKVEGVAGFHIMAIEWEEKVEEICQRAG
LLPRPQV
>A0A4S1ZR39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculum intestinale|TrEMBL
MKVTDIIAARQTPGFSFEVLPPLKGRGINQLFKNIDILCEFDPLYINITTHRSEIVFKDT
SDGLYRRVSERSRPGTVAVAAAIQQKYGIPAVPHMICSGFSKIETEYALIDLNFLGITNL
LLLRGDKAKHESRFTPNADGHAHASELQQQVNDFNRGYFIDGTKMDIITGETFSYGVAGY
PEKHEESPNPDIDLQYLKLKVDNGADYIVTQMFFDNEKYFRFIERCRNAGINVPIIPGLK
PITTMSQLNLLPKVFHVDMPSDLANELMKCTSDAQAKEVGVEWCAMQARELIAHNVPSIH
FYSLNATRSVERVARTVY
>A0A2E4BED2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacteraceae bacterium|TrEMBL
MDNKEIINLKELINNYTIETTPKIFEKISDLNNLLPKNTSIYITYLPNENYKKIIDTAKK
IKDEGFEPIPHLPARTIKNFSEVEKYLGMLSEISGAKKILIIGGSSYQNGNISSSMEILE
TGLIDKFNFTEVGLAGHPEGSPDISDEELDRAIIEKNKFVNNTQAKLYFVTQFFFETSSF
ITWEKHLEELGNKIDIHAGLPGPANILTLINFAKSCGIRNSINFLSKQALKISKLASTKA
PGKLVYELSKYKNSNSNSKLTKLHFYPFGGMKKTSRWIKALIDNEIRIDQNNDIEITNFD
L
>A0A2A5DHK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MKTTPNTRIPLRDALGQKVLLLDGAMGTELHARGIPFHGNFETANLEHPNWVREIHQGFL
DAGADAVVTNTFGANRYRLAKHQLEDKLGELLEAGGRLARESAGEHAYVLGSLGPLGVEL
EPLGRLSKEEAIEAFAESAKYLLPYVDGFSLETFDNVAELECAIAGVRSVSDLPILAFLT
VGDNGRTFHGTTAVESALRAEAAGADVVGFNCSSGPRVVLDAVLEAAKGGVQIPLAAKPN
AGMPREVDGRIFYENDPDYFARFARRFLQAGGVVLGGCCGTTAEHIRALSRAARAGSAQM
RRATLQPSVKPGAKVKAPDAGMDAVPLVERSRFAAGLARGRTVISVELVPPRTPDMTKLL
QAARTLDRFGVDAVNLPDGPRASARISNIACAAILSRETNIEPLLHFCCRDRNXLGMQSD
LLGAAALGLHNILAITGDPPYQGDYPNLTAVFDVDAIGLTNMITMLNRGLDLGGNDLGQQ
TSFCIGGALNHTALDLDRELERLFWKIDAGADYXITQPVFDADTLLELIERLPSHTPPIL
AGLWPLRSRRNAEFLHSEVPGVHLPEKVLKRMAHAEDRKQSAEVGIEIAQEIVEALQGKV
AGFQVAAPFNRIEPALEVVETIRAGS
>A0A7C3FBJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MKREKLIKRLKAKKPLLADGAMGTLLHERGVGFDQCFDELNLTNPSLVADIHREYIEAGS
EIILTNTFGANRYKLSRHGLEDKVTAINNAGVELTRRVVLASFKEIFIAGDVGPLGVRLA
PFGRVQPEQARDIFKEQINALYESDVDLLVIETITDLYEIREAISAAQSLNADIPIVASM
TFTRDDCTLLGDNPIKVVNTISNYGADVIGVNCSGGPNQLLRLLKKMHQALPEGIFWIKP
NAGWPEQVSGRIFYPASPEYFGNYALAFWKRGAKIMGGCCGTTPAHIAAMDKAIQSNTTK
VIFNDLEIKTVEAEVLKEEAQEPTKFSQKLTQGKFIFTIEMDPPRGLSTHKILAGASLLA
EAGADAIDIADSPMARMRMSPWAICNLIQKHINIETVLHFPTRGRNLLRVQGDLLAAHAL
GVRNVFVVMGDPTAIGDYPEAMDNYDLAPSGLIKLIKQRFNQGIDHAGSEIGQPTSFFVG
CALNLAAPDPEREMKVLQRKIRKGTDFILTQPIYDVTILENFLKQYRVFSKKIEVPIIIG
VLPLVSAQHAAFLHQEVPGIDIPEKVYQQLQSSGDEGAKLGIKQAIDLIHQLKQVAQGVY
LMPAFSRFDYAAEIIDKCSG
>A0A3L7SRJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MVGSVSPHHRSQAAHTVSIKDAYTGSRFGLSFELFPPKTPESEAVMWRTVDELLAFDPAM
ITCTYGAGGSTRGTTLDVLKGVLARHRLPVASHLTCVGSSVDELRDYLRESLAIGVAAIV
ALRGDPPKGETAFRPVDGGLRYASELVALIRSEFPELGILVAGYPETHQEAVSAQADLEN
LKRKCDAGGDVVVTQLFYDNVDFFRFRDRCADLGITAPIVPGVMPVTNYGQVRRIASLCK
AQLPESFTRSFEAAGDDEAAQFEAGVNYAARQVEELIAAGVPGIHFYVLNKSPATIRVLD
HVGMKRAEA
>A0A660V2F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
GSPGYNFSPIEKFLSAHQEKKAAIPGGFSFVGITVPQNPGGVANIDPSDVLAVIEKKNLL
DDLDYIPHLSCKDNNVDSLTSTLVGYRQRHIESVLALTGDKPITSQGVFEVESIGLLSLI
GKLNHQSITKAKPGQWDQVRQFCAGAAVSPFKYTEASLMQQYYKMEKKVAEGARFLVTQV
GWDWKKSLELAQYCKDNSISTPLVGNVYWLTTKTPAPRLMHDIKLPGCFVSDDLLAKLQS
ESIDEHIERAAQQVAMYKSMGYAGVDVGGVHDYDIFLKILNRADEIGDGWQQYKDNLYWP
AEKPFYLYDEAGRQVSLSKPKRKCNERFFDFMHRAILDSDYKGFHCLKWVLKLFRVNKES
GFTYKAFNAIEKSFKYCAFDCAECGDCYLPENFGYCTIGGCEKGMDNAPCGDSTVDGYCG
NNLERLCIGERIYDSAAAKTDGREKLRTMLNKPRIAALEHTSSIVNYLFGKDHTMTTPLI
GIGESIHASIPKTGKIMKELHDLGADAYTKESGPLNYIRALVEEQADDDAAYIAVNLDAF
GESDPQQAVGMMVDYTKLVRQWSKGVPICIDSSNDDVLIAGLKEWYNTDEVVKPPLLNSI
KTHTTDKMMALKKTYDFSFIGLLVSEDKATGPGGSHSVEELFGLAKEIFDKAMQYGFKPE
EIYFDSTVFPIAIDMPMEPGVPGYTYRAFETIKKIKTDPQMKNCHCSLGLSNSCRDLPGR
RIGIARAYTAKAMEYGLDAGIVNVTHRFGEKPADPGLVELVDAYAKLDGNMDNLTVAMER
MGQFCQSCKKPS
>A0A7X7YXG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MNRSAFEQQVSQRVLVGDGAMGTMLYQQGVFLNRCFDELNLTDSKIVRAVHDGYVAAGAD
FIETNTFGANRLKLSKFGLAGEVPQINHAGVRIAREAAKDAVLVAGSIGPLGCELTEHGP
ITFRAAGEMFEEQGRALVEGGADLLILETFSNPEELLIAIRSIAGLGDIPIIAQMTVNES
NETIYGERIDQAIARIAREEAVTAVGLNCSVGPSGMLGSLELVRHVTDKPIAVQPNAGMP
RQIEGRQLYMCTPEYMAEFAKRFFEKGARIIGGCCGTTPDHIREIVRAVRSISRAAARSG
TSISVQAPQAARAVPKTPQPLAARSRFGARLAAGETVASIEITPPRGVDVKAIVEKARQC
AEAGVDAINIPDGPRASSRLSPLVTAVKIQEGAGIETILHFCCRDRNLIGMQSDILGASA
IGVRNLLIITGDPPKMGEYPSATGVFDMDSVALTGVARSLNGGVDIGGNGFDPPTSLVIG
VGANPVAADLPREIDRFKQKVAAGAEFAITQPVFDADCLLRFLEATQGSRIPIIAGIWPF
TSFKNAEFMANEVPGVVVPPRLLDRMS
>A0A3M1GZA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MIELLRERVVVGDGATGTMFYRSGVPLDACYEALNLERPELVKSIHRQYVVAGAELIETN
TFGANRLRLEPHGLADRVAPLCRAGARLARAVAGDRAFVAGSVGPLGRRPGEECPADAEQ
IFGTAMEALAEGGVDLLVVETLLDRDELRAAVRAARSRTELPLVVQFAVTEGGYTPRGLA
IADAAREALELGADVVGANCGKGPREVCEAVEELVRAGLFDGDVLLSAFPNAGQPELLGG
RYIYVTTPEYMAAAASRLADAGVRLIGGCCGTTPADIAAMRRALRGRSAVPLESARDRLR
RERRARARELQAGPRPIEVPSRAPRAVAPALERLRFLREARPGSADPAIIVELDPPKDLD
VGRVIDGAQRLAAAGASAITIGDSPLAVTRMSAVAVGHLVQEAAGLPAIVHVGCRDRNLI
GTQGLLMGAHALGIRAVLGVTGDPASIGGQPGASSVYDTNSFGLVGMLAAMNRGEPVGAQ
PLAQRTAFTIGVAFNPNGLRITGQLRRLRKKVGLGAHFVLTQPCYDVARVREMYAAAEEL
GVPIFLGLLPLFNERMAAFVHNEVPGIDVPEEVSAELRGLGREEGRERGLARIERIVDAV
WDVAHGFYVIPPFNSPRHALAVMERIRAVARRRAPREREARTA
>A0A7C3F5P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MRLTDIWRSNAKPTLSFELFPARSEKAAVNLEMTIDALAALGPDFVSVTFGAGGSTRQGS
LQLLKKLKHEKGLEILAYFACYGLGPEEITAVLDDYLAIGVENVLAVRGDEPREGEFLPH
PDSLAHASDLVAFIRPKYDFCIGVAAYPEGHIDAPSVEQDLEYLKLKVDQGADYIITNYC
YDNQFFFEFVDRCRQAGIEVPILPGVMPIYSVKMMEMLAGMCGATITDEIRKGIAALPED
DKQALLAFGIEFGTRQCAELLQSGMPGIHIYTMDRSPSSLGIVQNLQAQGLL
>A0A7C5ARB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MKVGSHLEQILAAGYFAVTAELGPPQNADPAVIVRKASILKGYADAVNITDNQTAVVRMS
SIAAGVLVLQQGLEPVIQMTCRDRNRIAMQSDLLGAYALGMRNLLCLTGDHQSFGNHPTS
KNVYDLDSIQLLQMVAGLRDHKRFLCGEEIKGQEPRFFIGAAANPFADPFEFRPYRLAKK
VAAGADFIQTQLIYNVPRFAEYMRRVRELGLHEKVYILAGVGPIKTAAAARYMRDKVPGM
DVPNEIVERMERAVADIPKEDRKARTEAWKQEGIRICVEIIQQLREIEGVAGIHIMAIEW
EEAVPEIVRAAGLYPRPQVATPEGKEA
>A0A420T7C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDRIKAIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A564QD37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Syntrophoarchaeum sp. GoM_oil|TrEMBL
MQNIRDGKFVFTGELEPEKTTDLTELIEGAKKLLGQCVACNVTDNPQSMAYMSSLVASHI
IQRDSGMECVYQLRCSDRNSIALTSDLLGAGALGIKNVLALTGDHTALGDYPGSMPVFDI
DSGQLTYLIRRMVDEGLDLNGKPIEVPPKYHVGVAGNPNADPLDSEVLKLKRKVDAGAEF
VQTQVIFDVEIAKTFLKEMEKYKVPILIGIFPLKNYGTADYFDKYIPGVRVPKDLLTTMK
EASEIGDKEKKKARYDEINLDYYGDFVYEIAHNTSAAGIHVMAVAYERITPPLIERAKI
>A0A807M4S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. 275|TrEMBL
MGLLQDLKERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIADLGADITGINCRLGPYHMIEALTEVPIFSDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVQGLSPVTEKEVKIRREEEVI
SVRNERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A831T790|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermorudis peleae|TrEMBL
MSDRQGASQFGDGAEVEWVCRLLDNARLEILPTAKADEIAKGVPERYKLTVTSSPKLGVA
RTVELATELRRRGFTVVPHLAARAVRDRHELARIIDTLVGAGIDEVFVIGGDQEQPVGAF
SGALELLEVLSTLDRRPQTIGVAAYPEGHPKIPSSVLMDMLLKKQPYATYAILQLSFDAG
AILDWLRAARSQGFHLPVYLCLPGTLRIDRLLRIAVRLGIGQSLRYLEKQQGLLPQLLTG
GYRYDPWTLIESLLERFGPDHEQIVGIHWSTFNELTRTVEWIESRQRELRVTAR
>A0A7C6F568|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MIHPNWGIIPTPPGFSIRIRSGWSVQRRLNQGVDIGGQSIDPPTAAVIGVGLDPTAIDEK
RELDRFRQKVEAGAEFAITQPVFDPEALLLFLDKVQHFGIPIIAGIWPLASLRNATFLKN
EVPGVVIPDWVMDKMASVSSREDQLKMGIEIAQF
>A0A7J3S1V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrososphaeria archaeon|TrEMBL
MGDIEGRRRRGLEESIERRRHPIMVELPTPRGVDCSRALSFARKGEEYVDAFLVPDVPTG
RVRADPVAVSKLLLDAVTADVVSSISVRHHSLEANISRMLGLWIVGVRNLNIVMGDALPG
LSFPEHPSLGALKAIRLAKSMADGWVETSFGRARISGRPRFFVGCALLPNRRGEEERVKA
KVDAGADFFITQVSFEHYTLASFFDRLASQGFRFDRPVFVALAVMKAKRSLEALRGLDGL
YLPEKVAERLLSSNDLEEESIGLGMKVFHEAANSLKGRVKLGAYVLPLNGSGRSLELARG
LSDKG
>A0A2R7KNC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. HMWF019|TrEMBL
MKIIDHINNAKGKTLFSFELLPPVKGQSIQGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HPSGLLEKVAYRKRPSTVATCAAIMNKYRVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDSSFIPTPEGHAFASDLVQHVADMNNGKYLHEDMDDPEKTNFCIGVAGY
PEKHFEAPNLDTDFKYLKLKVDLGAEFIVTQMFFDNDKYRLFVEKCRENGINVPIIPGLK
PITSSKQLISLPKTFHLDIPMALSEAITSCKSESDVKEVGIEWMIEQCKGLKELGAPVLH
FYTMGKSGPTRRIAQAIF
>A0A415ZBE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. AM05-23|TrEMBL
MVNKMSSLLQQTLEAGKFAITAEMAPPKGTDFSHILEIADLLKGRVQGVNVTDFQSAAVK
ASSLAMCVELERKGLEPILQMTGRDRNRIAIQGEMLSAGHFGIKNMLALTGDHTTTGDNP
EAKPVFEMDSVSILQTAEVLMSGQDLAGNELQGSPDFYLGACVTPVFDPVEVQLIKMRNK
IRAGAKFFQTQGVFDIEVMREFKELTKDMDCYVLAGIIPLKSAGMAKFMNRSVPGISVPD
ALIERLTEAEDKAAEGIKIAGEFVAQLKEEGVCDGAHIMAIGAEENVPKILDIAGL
>A0A3M1HPU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium|TrEMBL
MRLDALYAERRTPTISFEFFPPKTEQGEEKLWATLEALSRYQPDFVSVTYGAGGSERART
RNIVVRIAQTTDLTPVAHLTCVAEDETQIRALLDDYAAHGVENILALRGDPPQDPAFRWP
ENFRYATDLIRFIRAHDHFAIACATYPEGHPESPNGPEDDARVLKMKQDLGACVAITQYF
FDNDDYFRFRDMAARFGVAIPIVPGIMPIRNFEQIVRFSERCGATIPDWLRERFAEVGDD
QDAARKLAIEIAVRQCEALLAGGAPGLHFYTLNQPDLTSAILNTLGFSRP
>L0RDD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maridesulfovibrio hydrothermalis AM13 = DSM 14728|TrEMBL
MKIVDLIKKNKPFLSLEFFPPKNRDSWPKFFEVVEKLKVLNPLFASVTYGAGGGTQDNSL
EIVKRMKQDAGIEPIAHLTCVGASPENISEFVNALQQAGVDNILALRGDAPQDDENFDFN
TQTFKHGSDLVTYVQKTHPDMGIAVAGYPEAHLESPSIKEDFKWMKYKIDEGGEFIITQL
FFDNRIYFDFCERMKAMGVNVPIVPGVLPIMSLKSAKFILSLCGAAIPGKFLSALEKAHS
EGGDEAVYKLGINFATKQAQELLDGGAPGVHLYTLNRAKACLEIGHALRFK
>A0A521KAG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRISDQIGRGRPVFSFEFFPPKTDQAANDLMATVADLKGLHKPDFVSVTYGAGGSTRTRT
LELVTRIQRELELDAMAHLTCLAHSESELCDVVGRLVGNGVENVLALRGDVPKDDPTALA
RGGFKHANELVAYLMDNYELDIGAACYPEKHPEAGTSDEDLHWLGVKVKAGAAFLITQLF
FDNKDYFAFVDRARKAKILVPILPGIMPITNVAQIERFTKMCGAKIPPELGARLQRAKDD
PAAVMAAGIEHAITQCRELLERGAPGVHFYTLNKSAATRSILAAIRRA
>B1L1W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum (strain Loch Maree / Type A3)|TrEMBL
MHIKELFNEKKLVFSFEIFPSKVTSSITTIYETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKDIIGE
YNYAFELIEKIKASNNFGISGACYPEGHIECKSLDQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQEKSINVPIQAGIMPVVNKKQIERIVKISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDIAV
>A0A4Y9RER5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. S30B|TrEMBL
MTSLAEARALLLSPLGPVARAGSNHDAVRVSFEFFPPKTDEAEANLWKAIRRLEPLNPAF
VSVTYGAGGSTRERTHRTVQRIIAETALRPAAHLTCVEASRDEVDEVIAGYKAIGVDHIV
ALRGDPPGGAGIGGVYQPRADGYANATELTRAISRAGGFDVTVGVYPEQHPESPSIDHDI
DVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLTRMCGA
CGASIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRADLVYAI
CRVLGVRETKVVA
>A0A4Q3S347|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIEHINSATKPLVSFEILPPLKGKGIQSLYNHLDPLMECKPAFINVTYHRSEHLFKKK
ADGTFEKVVVRKRPGTESICAAIMNKYNVDTVPHLICGGFGINETEDALINLNYLGIDNV
LVLRGDAAKNEANFEPEPGGHKYALDLLKQVTNLNAGVYLEEELKNTIKTKFCIGVAGYP
EKHFEAPNMDSDLQYLKQKVDAGADYIVTQMFFDNSKYFAFVNACRDIGITVPIIPGLKP
IYTIKQLTLLPKVFHIDLPLALSNEITKCKTDEEVEQVGKEWLLEQSKDLYKAGVPVLHY
YTLGRPQLIADVVNDFL
>A0A1Z3CFD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. polymorphum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEIGD
FNYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVDAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRK
>A0A353F160|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
RFPAKLLKRLSVADGDAAAIRQAGIDHAIEQCQELIEQNVSGLHLYTLNKSSATREIANA
LTF
>A0A3M1Q1J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRIRELLSTGRPCISFEFFPPRDEAGVQRLRRSLASLRELRPSYVSVTYGAGGSTRRQTL
ELVTHIQDDYQILPMAHLTCLGASRDELRDVLAKLADAGVENVLTLRGDPPRGDTEFRPH
PDGFAHASELAAFARSEFSFCLGGACYPEKHPEAESMDADLAHLKAKVDAGCEFLITQLF
FDNQRYFDFVARARACGIGVPIIPGIMPITNVAQVDRFTKMCGASIPSSLWDELQRLRDD
PHAVLSLGVAHATAQCIELLNRGAPGIHFYTLNKSAATRTILKAIQTVYPPARTPAGSWD
>A0A542H5M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SLBN-115|TrEMBL
MQPASTVRTAVGTSLLDDFSLEMTGKDVPKLEEARDTIPPGTRINVTFLGNEDLRLRLDA
ARAVKRLGFVPVPHISARRLGSRDDFERFLAGLRADGTSDNVFLVGGDPAHPEGPYADAL
SLIGTGLLREYGVRHVGIAGYPEGHPSIDGTALWSALRDKHAALAAQPLEAGVTTQFGFD
VDPVLAWVEEVRSRGVGLPIRIGVPGPAGVRRLMAYAARFGVGTSASVVKKYGFSLTNLM
GTAGPDRFLRALAAAHDPARHGELKIHFYTFGGLGATSDWAARFRKDSPA
>A0A5M8US20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. ICMP 7243|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
SGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFRDYMKKVRDLGLHEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEIIKRIEGAEDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEMVHDSGVLKGRRPWKHEANRTDALVAERLERIREGKEENQQEMAEAAA
HHPPHQTH
>A0A4Q3SBW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIDHINNATGPLVSFEVLPPLKGKGIEALYKHLDPLMEFKPAYINVTYHRSEHVFKKK
MDGSFDKVIVRKRPGTESICAAIMNKYNVDTVPHLICGGFSVNDTEDALLNLQYLGIDNV
LVLRGDAAKNETSFESEPNGHRYASELLKQVVNLNAGVYLEEDLKATNKTTFCIGVAGYP
EKHFEAPNMQADLKYLKTKVDNGADYIVTQMFFDNAKYYSFVKACRDIGIEVPIIPGLKP
IYTKKQLTVLPKTFHIDLPADLSNEILKCKTDDEVEKVGEEWLLEQSRDLRKNGVPVLHY
YTLGRPLMVANVVKNL
>A0A524CWS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MNYGCVANPNSNPREPEILKVGRKVEQGVDFIQTQTAFDIDEAKDFLKDLEQFNVPVLLG
IFPLKSHGIAWYFDNYIPGVSVPKDLLKGLKKAEKENKGDKPAKYAAIDKINIEFFKPFI
EEIRKTTKAAGIHCMAVEYERLFEPLLKEFEEYTYL
>A0A6N7QCH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sontii|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
RFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQAHDALSDLRHFKAKVDAGADAAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAEAIREFGADVV
ATLCQRLVDGGAPGLHFYTLNLAKPTTNVLARLRGDVAAG
>A0A842SZC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MTNRPAYSNLCKKIEEGHFTITGELEPKKILDLEEIIESAKEMKRTKKIAAANVTDGPQG
DAYMCSLVPSYKVQEEAGIEAVWQVTVRDRNRVALFGDVLGAAVMGLKNILVLTGDHTAL
GDHKKGRAVYDLDSTQFCDMLSKMIDEGTDLEGNELKGGKIEMNYGCVANPNSNPREPEI
LKVGRKVEQGVDFIQTQTAFDIDEAKDFLKDLEQFNVPVLLGIFPLKSYGIAWYFDNYIP
GVSVPKNLLKALKTAEKENKGDKPAKYAAIDKINIEFFKPFIEEIKKTTKAAGIHCMAVE
YERLFDPLLKEFEEYTYL
>A0A524EY29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAKRPAYSQLCKAIEEGHFVFTGELEPKKILDLSEIFHSAEEMKKTGRIVAANVTDGPQG
DAYMSSLVPSYLIQEKVGIEAVWQVTVRDRNRVALFGDVVAGAVLGLKNILTLTGDHTAL
GDHKKGRAVYDIDSTQFCEMLSIMIDEGTDYEGNELEGGKIEMNFGCVANPNSNPREPEI
LKVGRKVEQGVDFIQTQTAFDIDEAKDFLKELEQFNVSVLLGVFPLKSYGIAWYFDKFIP
GVSVPKDLLKALKKAEKDNKGNKQGKYAALDKINIEFFNPFIEEIKKTTKAAGIHCMAVE
YERLFEPLLKKYPKYV
>A0A1S1FZA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria sp. HMSC70E02|TrEMBL
MSYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHSIVKRIQQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A5D4GW10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium microcysteis|TrEMBL
MADPRLSRRTDIGDRIKVSFEFFPPKNDEMEGRLWETITRLEPLSPQYVSVTYGAGGSTR
ERTARTIGRILTGSGLKPAAHMTCVDATREDVDAVVRDFASLGVTRFVALRGDPAAGVGE
AYRPHPQGYSNGAELVGAIRRIGDFEVSVSAYPEKHPESADFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGVLPIHNFAQVANFSARCGTHVPAWLAERFA
GLEKDPQTHALVAAAIAAEQVLDLVERGIEEFHFYTMNRADLAFAMCHLIGIRPQVGTAA
AAA
>W9XUT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capronia epimyces CBS 606.96|TrEMBL
MHISQKLALAHENKKPTISFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
QLTCEMVNAAQSHYGLETCMHLTCTDMERTQVDEALRLAYKAGCTNILALRGDPPRDQEK
WEAKDAGFRYAKDLVRYIRARYGNHFDIGVAGYPEGCDDHRDVDLLVEHLKEKVDAGASF
VVTQMFYDVDIFLGWVQKCRDRGIHVPIIPGIMPISTYAAFMRRANWTKCHVPPEWYEAL
EPVKNDDAAVRDIGKVLIAQMCRRILDAGILHLHFYTMNLAQATRMILEELALTPETSGR
RLEKPLPWRQSLGFGRREETVRPIFWRNRNTSYVARTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANIKLWGKPRSLQEIITLFVRFVQGDLDKLPWSEGSISAEADSIKSDLI
GLNQRGLLTINSQPAIDGAPSSHPVYGWGPPGGWVYQKAYLELLVFPSIFNTVLERLNAN
ENLTYYAVNRKGDLHTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WSRCYPAGSGPRKLIEKMMDECYLVNIVNNDFHQTHEIFKVFEDLRVQDLDAVFEDTPVD
LHKNGTREVLKGDTPVTDVEKSILNRDQQKVPFQTTGGGLPN
>A0A0E1W171|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei 1710a|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A0W1QPL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. WG|TrEMBL
MAPPLFADVAGDVAVSFEFFPPKTEKMEETLWASIETLSPLGPRFVSVTYGAGGTTRERT
HATVSKIARETPLAAAAHLTCVEATREEIDQIAEEYWAAGVRHIVALRGDPPRAGEKYRT
HPGGYENAADLVAGLRRLHPFEISVSAYPECHPDSPSPEADLDNLKRKIDAGANRAITQF
FFEAETFLRFRDRAAAAGIDAEIVPGIMPVMNYASVVKMSAMCGTDVPAWMEKLFEGLDE
HPGARQLVAATLAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGLRPRQQAAVAAA
>A0A3G2FSE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. 1608163|TrEMBL
MNAAKTEATGFPVSLEFFPPKTPEGAEKLRAVRQQLYALHPEFCSVTYGAGGSTQEGTFT
TVREILAEGVSAASHFSCIGATRQSVREQLAVLKGMGVRRLVALRGDLPSGYGAGGEFQY
ASDLVTFIREETGRDFHIEVAAYPEVHPQARSPEADLKAYVAKVQAGADAAITQYFYNSD
AYFRFLEDTQKLGANIPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLEL
>A0A497QPW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MYLRQVYATKHPAISFEIFPPKGNYPINQLLEQLEIFSQLKPDYISVTYGAGGSTKDKTI
KIAGMIKENFQIEPLAHLTCITSTKDQIHSIISDLSNHDIENVLALRGDIPTDPNFVFPT
PLHFEFASDLIRELRKERKFCIGAAFYPEGHIEAPNREIDFKNVAYKAKQGTDFLISQMF
FDNAYFIKSVKKLREMGVNQPISAGIMPITNIKQIQRIADLCGATFPPNLLKELKTRADN
PKHVEDFGIQYATDQIADLLNSGVEGIHIYTMNKPRIAEKIIQNIRNLR
>Q2G121|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus (strain NCTC 8325 / PS 47)|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLYGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A8G0EI44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. DSM 110487|TrEMBL
MKSTEESVVAHVPPDVPLTISTSHAKGPEPTVDLAVRLARHGYSVTPHLAARQIVDGAHL
TDLVARLREAHIDSAFVIGGDSPEPAGRFGDALTLLEALDQVGNPFQRIGIAGYPEGHAR
IERGLLEKAFERKAPFATHAITQICFDADATVGWARHVKQRGIRLPIRVGLPGVVSRQKL
VRISAGLGLGQSARFLLKQQSLFWRFFLPGGYHPGRLARRLAPYLQLADAHLDGFHFFTF
NEVASTEAWRRSLLDRVS
>A0A841TQ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella xylanilytica|TrEMBL
MLKQKIADRQAGILTYGITPPKVTHDAEKIAEIARKQIERLEGSGIDGLVLYDVQDEADR
IDQDRPFPYLETIDPTRYSKEYLSGFDVPKIIYKVVGKQSKEEFADWLRADGGEDRFSVF
VGASSSRQAVTMRLPEAYRLGARLNANLALGGVVIPERHESKGDEHLRATGKQQDGCSFF
ISQAVYDVEASKNFLSEYYYYCMEHGIAMAPILFNLAPCGSQKTLEFMKWLGISIPKWLE
NELVHSQDILDKSIRLSRKIFEELFEFGLEKGIPIGCSVESVSTRKVEIEASVELLREMK
LFMESRLQVGAAALRG
>A0A7W2H288|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MVQIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKVF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMNKVRDLGFHEKCFILVGV
GPLASAKTAKWIRSNVPGIHIPDHVIARLEGAADQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGILKGRKPWKREHARADDMAAERMREIGSDPVQDQQEMAARAA
HPQPH
>A0A7J5W2T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKLTKHIARRGGKTLFSFELLPPLKGENFEGISQAIDPLIEFNPISIDVTYHREEIVYKE
RGNGLLERRTVRKRPGTVGISAAIKFKYNIDVVPHIICGGFTREETENALIDLYFLGIDN
ILLIRGDNPAGEKVFRPEPEGNRYALDLVNQAVNMNRGIYLEEGIINANPTGFCIGVAGY
PEKHAEAPNMASDIAHLKAKIDAGAEYIVTQMFFDNSAFFRFEKACREAGITVPVIPGIK
PLSTFSQLSTLPKTFSIDLPESLVLEAEKCRNKEQIRDLGVEWAIAQSKELIKHGVPVLH
FYTMGKSDNIQKIAKAVF
>A0A0A1UU37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium robertsii|TrEMBL
MHIKDMLAEAEKGGQPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLDKVNAALQKAYKAGCTNILALRGDPPRAQEK
WTAAEGGFHYARDLVKHIRATYGDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGKVRERGINIPILPGIMPIATYASFLRRAKHMQCKVPDHWMTAL
EPVKNDDVAVREIGKTLVAEMCRKLLANGIYHLHFYTMNLAQATRMLLEELTWAPCAERP
LQQALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTTVQDIASIFVKYLNREIESLPWSEAPLTGEANAIKDNLIQ
LNKRGLLTINSQPAVDGVKSSHPIHGWGPSNGYVYQKAYLELLVPASIFTEMVKRVEDKP
TLTYYAVTKDGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGTDW
AHCFESETPSRVLLDQIMNEWYLVNVVNNDFHENQTIFDLFEGLEVNGLDTPVAV
>A0A1V5H0L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium ADurb.BinA179|TrEMBL
MLVRNILKEQKTTFSFEFFPPKTPEGWDRLFLTISDLIPLKPSWVSVTYGAGGSTREHTH
NLVVRIRKETDLTVVTHLTCVEASRGDVAAILERYDSEGIHNILALRGDPPLGQREWKAG
PEGFCYATDLVSFIKTRFPHMCVGVAGFPEGHPETRNRLQEIDHLKAKVDAGADYIITQL
FFDNRDYYDFRERCELAGITVPIIAGIMPIISRSGMIRMAELAARARIPAPLLRSVQRAS
SNESVERVGIHWATEQVRDLIHNHVRGIHFYTLNNAKATLKIYEALGVADSLQLT
>A0A3M1N025|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MHVAEILARETGPFISVEIIPPRRGGRIQQVYDAIESLLPYRPRYINITSHAAEVIWQEQ
PDGTFRRRVKRRSPGTFGLCAVIKYKYDIEPVPHLLCHGFTREETEDALIELHYLGVENV
LALQGEEKYARPPRPDRTVNQYAVELVEQIIALNHGRYLDELTDAQPTNFCVGVAAYPEK
HYQAPNLAFDLANLKRKQDAGASYAITQMFFDNQLYYT
>A0A2D8HF74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sneathiella sp|TrEMBL
MSGISESAATAGLLSAAGGRSKVEVSFEFFPPTTDKLAEKHWEALTRLTPLGPRFVSVTY
GAGGSTRERTHALVSRIRNETELEPAAHLTCVGASKGEIGEIADLYWESGIRHIVALRGD
PPEGQGHFTPHPDGFTGSVELIEFLKKRHDFEISVGCYPEIHPEAKSSLADIEYLKRKMD
AGATRAITQFFFDPETYLRFVDRALAHDITIPIVPGILPVTNFAKVRQFSKQCGAQVPAW
LAHLFEDLDEDPATRNMVAAMVATEQCLRLQRAGVGQFHFYTLNRADLVYSVCHTLGIRH
KKSI
>A0A524HU56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSHNPFAAGKEPLSVSFEFFPPKSPEIEQQLWSAIERLAPLQPDFVSVTYGAGGSTRGRT
HATVKRIVEETALKPAAHLTCVGASRAEIDEVIRDYWAAGVRHIVALRGDMPEPGTAYCA
HSEGYQSTAELVAGIRAIADFDVSVAAYPEKHPDSASVDEDIEILKKKIDTGASRAITQF
VFDNDAIPRFRDRVLAAGIDVPIVPGLMPTTNFSGTRRMAARCGARIPDWLCEIYDGLDE
DFPSRKIIAGALLAEQVRALRSEGFAQFHFYTLNQSELTFAVCNLFGIKPVKEAVHL
>A0A2E2M5I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSDTNPLGAHLPLDPKPGHSSRGRLERVLRRGEFAVTAELNPPDSADPDEVYDRAAVFEG
WVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMGVC
NIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDDAKFLSGRKLTTPPQVFLGAAI
NPFVPPQEFRPMRLAKKIAAGAQFVQSQYCFDVEMFRTYMSRVRDLGLDEKCYIMCGVGP
LASARTAKWMRTNVPGVHIPDHIIKRLEGAEDQKAEGKRLCIDIINEVKEIAGVSGIHVM
AYRQEEFVAEIVHDSGVLKGRKPWRKEPNFANEMAEARLEESEATAGISPHNLAGAAAEN
EG
>F5T187|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga aminisulfidivorans MP|TrEMBL
MAKNLTLSCEFFPPKTEKGIANLSAVREKLVPLKPEFFSVTFGAGGSTQDNTMDAVIDIQ
KQHAVTNIDAAPHLSCVGSSAERIRALLDTYRNNNIHRIVALRGDLPSGMQAPGDFRYAN
ELVEFIRAETGDFFTIEVAAYPEVHPQAQSAEDDLINFKRKVDAGANSAITQYFYNIDAY
RYFVDNCQKHGIDIPIIPGIMPINNFTQLARFSANCGAEIPRWLRKKLEAFYDDSASMNA
FTVDFLTDFTQQLIELGVPGIHFYTMNKVDPTLTICDRLGLIK
>A0A2A4XVU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MNKELNVSFEFFPPATEKMEEILWKSVKRLEVLKPRFVSVTYGAGGSTRERTHNIVTRLA
NDTSMVPAAHLTCVDASREEIDEIVQNYWDEGVRHIVALRGDPKAGIGEKYIPRADGYAN
AEALVKGIKQIGDFEISVAAYPEQHPESGSLKADLDNLKAKIDAGATQAITQMFFDNEQF
YRFLDECEKAGINVPIIPGIAPVINFKGTVKFAKMCGTSVPRWLHRRFDGLDDDEETRRM
VAASVVVEQVRDLYAHGVRDYHIYTMNRAELTYTICHQLKNIG
>A0A4Y8JTB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT1-51|TrEMBL
MPNTSDPDCGNIPFSFELYPPKSDAATSALHATIERLAAAGPEFISVTYGANGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSNAEASQLIREFLDAGVRSFLALRGDPPEGVREGEAF
LGDLGSAAELVQLIHRVQAEREPYRESVIPGLPAARSIKRDRKKVRIAVAAFPNGHPRSR
STAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQRDIGIRQATELARELIAGGAPGLHLYAFNQHE
TVLSVLDGCGLLVPAPSVSAPSASDPAKEYS
>A0A3M1Z584|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEILENSKETVFSFEILPPLKGKSIQEIYDGIDPLLEFEPKFINVTYHREEYVYKKR
EKGYLEKVSIRKRPGTVSICAAIKNKYNIETVPHLICGGFTKEETENALIELNFLGIDNV
LALRGDPIKTETHFVPEEGGHRYAVELVEQIKKMNNGIFLDEDIKNAQPSNFCIGVAGYP
EKHFEAMNLKIDLKHLKEKVDAGADYIVTQMFFDNQKYFDFVEKCKETGINVPIIPGLKP
ITTLNHINFLPKFFHVDFPEPLAEELEKCTSNEQVKQVGIEWAIYQAKELKKAGVPCIHF
FTMGKSEATRLIAKEVF
>A0A662BFP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MRVIEAIEKAKGSPLFTFEILPPEKGMDIKSIYDTIDPLIEFDPSFIEVTYHREEVEFRE
HGDGSIERKVLRKRPGTVGISAAIKFKYGIEVIPHIICGGFNIEETENGLIDLHFLGINN
LLAVRGDNLPGEKYFSASKGGHHYASDLIRQIMDLNNGIYLDEELKNTAPTNFCTGVAGY
PEKHAESPNFQTDIKYLKEKIDAGAEYIVTQMFFDNSMYFDFVDRCREAGINVPIVPGLK
PIATKSQLNTLPKTFSISIPEDLQLEIDKCKDNKQARQIGVEWAIMQSKELVAGGAPVMH
YFTMGKSDNIRQIAKAVF
>A0A3D0N0Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHLAKAKNPFISFEIIPIPRGGDIGKIFAIVEELMKYNPPFIDVTSHSAEVQYEET
PTGIRKKVKRKKPGTIGISVAIKNKYNVDTVPHLLCRGFTKEETEDALIELNYLGIENVL
AIRGDDKGYIKPVSEGKTRNEYACDLVKQISDMNKGKYLDEDLLDATPTNFCIGVGAYPE
KHFEAPNLRSDVKTVKSKVEKGADYIVSQMFFNNANYFNYVNMCREEGITVPIIPGLKIL
TTKKHLTSIPANFYIEIPDELSEEIEKAKPEHVIDIGVEWAYKQSIELLEKGAPSIHFYV
MQNVKPVKKLLEKLKL
>A0A3D4AIB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHIKNAKSTLFSIEILPPLKGKDIQSIFDGIDPLMEYKPAFVDVTYHREEFVLRKR
KDGGFDKVFTRKRPGTVAICAALMNRYKIDTVPHLICGGFSKEETENALIDLNFLGIDNV
LVLRGDSIKNEPNFIPEPDGNKTSLELLHQVKNMNNGIYLDEEISNATPSNFCIGVSGYP
EKHFESPNMNSDLRWLKQKIDNGADYIVTQMFFDNKRFFEFLDQCKKMGIDKPIIPGLKP
LTTKKQLTVLSKLFHIDFPEELVLEVEKCKDDKAVKQIGIEWAIQQSLELKNASIPVLHY
YTMGLSEATKAIASKVF
>A0A424HBA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. TMED155|TrEMBL
MGRSLEQALASGQSVITVEITPPLGADPSRALAAAESLRDRVQAFNVTDGSRAVMRMSSL
AMCRLLQERGLEPVLQLGCRDRNRIALQGDLLGAHALGIRNVLCLTGDPVRAGTQPEARS
VFDLESVRLLQQVQALNDGIAPTGQPLVDGASALFAGAAADPQSGSWSGLKSRTRRKAQA
GARFIQTQMVMDAEALRRFCGEIAGPLGVPVLAGVFLLKSAKNASFINRVVPGVHIPQEL
IDRLAAASDPRQEGIEIAAEQVRAYSAIASGVHLMAVKAEESLVEVLDLAGLPQVVAQV
>S7N558|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myotis brandtii|TrEMBL
MDHLKPEVLPARHCCPSLGMRALEAGIMRFSVPPSISRNSAMVNEPRGNGSPNPCLEGSS
SSGMESPKDSSRCSSPGLDPERHERLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISG
FDQMGAGGPLFIDVTWHPAGDPGSDKETSSMAIASAAVNYCGLETVLHMTCCRQSQEEIT
GHLHKAKRLGLKNILALRGDPVGDQWEEEEGCFRYATDLVKLIRSEFGDYFDICVAGYPK
GHPDAESFEDDLKHLKEKVSAGADFIITQLFFEADTFFHFVKACSAIGITCPILPGIFPI
QGYHSLRQLVKLSKLEVPQKIREVIEPIKDNDEAIRNYGIDQAVSLCQELLASGLVPGLH
FYTLNCRKATTKVLKRLGMWAEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQ
DWDEFPNGRWGHSSSPAFGELKDYYLFYLTSKAPREELLKMWGEELTSEESVFEVFVHYL
SGEPNQSGRQVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVG
WGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYEQRVNYHIVDVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWVKQWGKLYDEESPSRMIIQYIHDNYFLV
NLVDNEFPLDNCLWQVVEDTFELLNRPGARGDPAP
>A0A497CJP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHIKNANGNTQFSFEILPPLKGQHIQSIFDNIDTLMEFKPPFIDVTYHREEYVFKE
QENGLLKKQVVKKRPGTVGICAAIQNKYKVDAIPHILCGGFTIEDTENFLIDLDFLDIDN
VMALRGDAVKSEAYFKPEKEGHVFASDLVSQIEDLNTGIYLDEDLQNTSSTNFCIGVAAY
PEKHMEAPSLDSDIHFLKKKIKKGATYIVTQMFFDNQKYFDFVDKCRKGGITVPIIPGLK
PIATKKQLNLIPHRFHVDLPEELIIAVVKCKDNKAVREVGIEWCVQQSKELQKAEIPVLH
YYSMGKSDNIKAIASQIF
>A0A414VCV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM20-15AC|TrEMBL
MRVDEVFKQAASQGTTPISFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAHARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A3D5HCB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
KLGNYPDATAVFDVDAIGLVNIIHRLNHGLDLAGNPIGDPTGFCIGVGVNPGAINLDEEL
RRLDWKIEAGAEYVVTQPVFDIRILERFMKRITHVKLPLLCGIWPLVSYRNAEFMNNEVP
GASVPPEILDRMRKTTTKEEGFAEGVKIAKETYQYVKGEVAGIQLSAPMGRIEGVAMILG
K
>A0A7E5VPP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoplusia ni|TrEMBL
MSEENKITELIKRKGKFSYSFEVTPDVSEDELFSLKEDPVFFSVTWHAKQHQCKDLNIGP
VRIASILRSKQKHVLLHLSCDMLKTDYLDELLTVLQERNICNLFLILGESYDPNSSDFKN
TSEVIKYIRSKTGQYFCIGIPGFPGCNDEKLQQIKDKIELGADFIMTQALFDSDGFQTLI
KRCEKMEIKVPIIPGIFPFETLQQLNGFINMCKIKVSEDLLTAINDKEKMNRPCSEIIKL
LLQELMSKCNTSHFHFFTLNKLRNVEKYIAQIK
>Q189R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridioides difficile (strain 630)|TrEMBL
MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAANVTDFQSAVMRATSLA
TCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLLALTGDHTSVGDHPQAKGV
FDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTPEYSPIEVQLLKMKKKIKAGA
KFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSPGMAKFMTANVPGIFVPDEQIER
LRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIMAIGAEENIPAILDAAGL
>A0A2G6HMZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiothrix nivea|TrEMBL
MTASVSTLSGNQNKPTGPEFSFEFFPAKTPRMERNLWRTMGQLELLNPAYFSMTYGALGS
EREHSLNMVSSMVKEGHVPVAAHLTAAGHTRDSLLELVRHFHNEGVQRLVALRGDAELIE
GGMTDVAVMV
>A0A2P7QWJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zobellella endophytica|TrEMBL
MGFHSARHVEALNQSLAELNGDINVSFEFFPPNSEQMEQTLWHSIERLKTLAPKFVSVTY
GANSGTRDRTHKVIKDIQDKTGLVAAPHLTCIDASRDELRGIARDYWNNGIRQIVALRGD
LPQGVEKPDMYAADLVSLLKEEADFDISVAAYPEVHPEAKSAQADLLSLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTIGIDVEIVPGILPVSNYQTLIKFAGFSNVKIPGWMHQRYQ
GLDDDQNTRNLVGASIAMDQVRVLSREGVKDFHFYTLNRSELTYAICHTLGVRPQPAAAK
>A0A1F9DC59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_54_18|TrEMBL
MGWRERLKSGSFLTIVEALPPKGVDVKRFEEQLIPVKGRVEAISVPSLQGGIMRMSSWAA
CRYLLDKGYETICEISCAHQNRVAIQAELLGAHLLGLENVMAAVGDDPKLGDHPETKAVF
DIDLLELLEAIKKLHRGYDMSGGDLEGAPRFCVGARLDASAQGHVLDLEMKEMEQKIRLG
VEFFITTSVYDLAQFEAFMQKARSFGVPIIAGLMVLKSAGMARYINKHIEGVMIPEGIIE
QLMKAPDKIAASIDIAAELITGERALCQGVNIVSMGWEDKVPRLLDAAGL
>A0A368UU97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter nauticus|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTREEIGELLDVYKENGINRIVALRGDMPSGMGASGELRYAN
ELVEFIRQHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEQMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTDMCEKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A2M7BK57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium CG03_land_8_20_14_0_80_58_14|TrEMBL
MKSGSNLEKVFVNGHFAVTAELGPPKNNDVSVIQRKVDFLRGYVDAVNITDNQTAIVRMS
SIATSAFVIQMGMEPVMQMVTRDRNRIAMQSDLFGATALGIKNIVCLTGDHHTFGNQVNA
KNVHDLDSVQLINLVKTMRDEKTLMGGEEKFEGDIKLFIGGAANPFADPFEFRALRTAKK
AAAGVDFIQTQCIYDMERFKEWMKMIRDLGVHEKVHIMAGITPLKSAGMARYMAKNVAGI
TIPDAIIDRMAKAAKGSEEGIKICVEQIQEVREIEGVHGVHIMAIEWEQMISKITEMAGL
LPRPKVE
>A0A2D5U7V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MIXDDEPXAGENXPILPXHDSPGRFERVLRAGHFAVTAEIAPPDSADPHEVYARAAXFDG
YVDAINATDGSGANCHMSSVGMCALLSRRGYSMIMQMSCRDKNRIAMQGDVLGASAMGVS
NILCLTGDGVQSGDHPQAKAVFDMDCMTSLQMLCGMRDKGQFLSGRKISSPPQVFLGAAA
NPFAPPFDYRPLRLAKKIAAGAQFVQTQYCFDIAMFKDYMXKVRELGLHKXVFILPGVGP
LASAKSAEWIRSNVAGVHIPDAIIKRLSGAQDQQQEGVNICIDMINQIREIDGVSGVHIM
AYRQEQRIAEIVEKTQVLGXRMPWHPNR
>A0A2Z4V383|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ICC1|TrEMBL
MALGTASSWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVT
YGAGGSTRGGTVRATEQIAADTTLTPVAHLTAVDHSIAELRNVIGQFADAGIRNMLVVRG
DPPGNPMGEWVAHPEGVHYAADLVRLVKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFHPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
AAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A5B0HAW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia panacisoli|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLALLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
DGLEAAPHLSCIGSSKESLRAILNQYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFANKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCRRLIDAKVPGVHFYTLNGAAATKAICERLGV
>A0A1M2UVY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter nauticus|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRAEIGELLDLYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISDREKIAF
>A0A2E0LGF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MDACNSAGIDRPIVPGIMPITNYESLRRFSIRCGAEIPRWLQYRLADFGDDAAGLRSFGE
EVVTRLCERLLAAGAPGLHFYTLNQAEATAAILRALGRPEST
>F2QR60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1)|TrEMBL
MTKIIDKIKELKGEPFYSFEFFPPKTDNGLRNLLARLGRMSMLNPLFVTVTWGAGGTTSS
KTLDLAITCQKDLDLTTCIHLTCTNTSKKLIDNALKAAYDNGIKNILALRGDPPREAQEV
AVDQDFKYAIDLVRYIRGQYGDYFCIGVAAYPEGHVEGNDDSEQSIDHDMPYLLEKINAG
ADFVVTQLFYDADKFCTFYNTLKQRLGRDVVVIPGLMPINTYQLFQRATNLSHASIPPAV
GQLFPPDVRHDDDKVKDIGVKLMIDIVDQIYNETHGEVNGYHFYTLNLEKSVAQIVDKSS
LLSPRLTVSSRFENAIESSSEDEKEQNQQTKTIIAISSGEGTMGKEATWDDFPNGRYGDS
RSPAYGEIDGYGPSLKVSSSRAYKLWGYPVDLDDITKIFIAYLSNRITALPWSELGLNPE
TGLIQEELIQLNEKHMFTISSQPSANGVKSTDKLFGWGPSEGYVYQKAFVEVFINKKQWN
EEILPNLQGHKSVTWYLGDCNNAFDTNIKIPLSSNSVTWGCFPDKEIVQTTIIGEESFQA
WNEEAFNIWREWQKLYPKNTASYNLLGSIINNFYLVTLINHDYANDNNNLWEILLQ
>A0A139NPW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. DD13|TrEMBL
MSQHTPSLSFEVFPPNPAVGNEKILRALDDMQGLAPHFISVTASNNKYNIKETTVALANH
IQNELEVPTIAHLPAIYLTKESVAETLQELDEVGVHRILALRGDIIPDVAPQKDFRYATD
LISFIKEEQPHFEIVGACYPEGHPDSPNQIIDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FRDKCILAGIDAPIHAGVMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARYISDATRSLFYHRRDFVL
>A0A0J5WJ12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cepacia|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTDLCRRLIDAGVPGLHFYTLNAAAATRTICERLDV
>A0A0L6CGP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteipulveratus halotolerans|TrEMBL
MTVAAGRNVRSGAVSIPQMLAQEGTAYSFEFFPPKDDAAEAVLWESVRRIERIRPSFVSV
TYGAGGSTRDRTVRVTGRIAAETTLVPMAHLTCVGSSVHELRQVIGEYAAAGISNVLALR
GDPQGGLDAPWVAHPEGLDHADDLVRLVRSLGSFTVGVAAFPDKHPESRSLEEDAETLVR
KADAGAEFAITQMVTDVDSYLRLRDLVAARGRDLPIVPGLMPVTRHGQLERMTALNGQPL
AAEVVRRIEAVKDDPDAVRSEGIAIATEHATRLRDEGAPGIHFITMNRSTATLEVFDNLQ
>A0A8G1D423|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 2hn|TrEMBL
MSLLKTTLDANAFTCILEFVPKPGAERFATLETLMARTRLCSWPLTVAIGDRVSSALDMS
PLEAFGSLATPVPALLHFSGKDRERRDLLAQLQRMDAAGLDQLLLLTGDRLPGHNPGERP
VRYLESVTALQIVRQARPHWLLAAALNPFKYQEAEGGAQYCKAEKKLAAGADLLILQLGF
DIDKHQEAFDWMQRQPRPKPLMACIMALTEGRAGMLDHVAGVTVTPSMRALLAAETAVSK
AYAKERANHRLALQVIGLKLMGYAGVHLSGIHEVAQFEALEQAIDALQAQFTSLQDWAPA
WEAAWQAPGLTPVTFHPPGHAWRFGQRQITASNKEKVRYHLLSAMHHQLFSRTTALSKAF
GWTVTRPLWANPTAAQWLHHLERRIKRPMVGCDTCGSCRLEDTLYICPETCPKGLANGPC
GGTNLDRCEFGDRECVHSAKYRLAVSVGQTEVLRERLIPCVQVENRHRSSWPVWFDTTTT
SPPTTQVGATAELND
>A0A497BQ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSLREKLASGKFVVTAEVGPPKGVDIEEMKKNAELLKDRVDAVNITDQQSSVMRIGSLAG
AHLVKQWGLEPVFQMTCRDRNRLALQSDLLNAYVMGIENVLCLTGDHVALGDHPDAKPVF
DLDSVSLLAAIKGLEQGRDLGGKELAGSPRFFSGASVTPCAEPLEPQIIKMEKKVKAGAQ
FFQTQAVYEPRQFETFMQSVKHLNVPVLVGIVLLRSAAMARFMNTNVAGIFVPDALIEEM
DKAEKKAAKGIEIAARLITEMKDMCQGVHIMAIGMEDRVPAILDAAGL
>A0A7C4G785|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPIFTPGRRWQPPFYPFKKEPLGARLLAGIEKLVKGPLFGCRMCGNCLLQETAFICPMEC
PKGIRNGPCGGSTSEHCYVDETRPCIWYKIYDRAFKMGREEYLLEVLPPLDWNKVGTETW
GDVVKQVRKIGTKNVVTGLLSKDPVKRTVVWDSIFRPVRQPDWWQGDAEYHPPMYTEPIS
ELERRLKAGEFVVTSEVAPPMTVSTNKLLQNIELIKPYVTAINFTDSPSATPRMSSWACS
VMAVQAGAEPVMQIAARDRTRVGLQAEVLGANALGVRNILCLSGDSMRMAPDPRGRMDVV
DIDSIQMIWILRRMRDEGKYLDGRAIKFPPKIFIGAAASPYASEPRFQAIREHKKVNAGA
QFFQTNLVYDIDGLEIWLNALAKRNILDKVYILVGITPLKSYKVAQYMHNEVPGVFIPDK
LMKRMEKAGDGASEEGVQIALELIEAVKKLQGVHGIHLMAVGWEEIVPRIVQEAGLAPKG
APKNEAKTAEVIVNS
>A0A523HNL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSNRVKFLDWLASGKPILADGAMGTQLHARGIPFEACFDELNLSRPELILDIHQEYLQAG
ARIIEANTFGANRHKLSSHGLEHQVEKINAAGVALAKQAIEETGADALVAGSVGPLGVRM
APFGRVKREEAYEAFKEQITALEQAGADLISLETQSDLYELREGIQAAKVVGDLPVIASV
TYTRDDRTLLGDTPAQAARLLWESGADVVGANCSGGPAQLLRVLQVMRRAVPEGKFSVMP
NAGWPEQVGGRIMYAATADYFAEYARAYTQAGACIIGGCCGTTPEHIAHMRTAIEGVEVS
QVRIISIETDEDLEKLSSGQTGATHLSSKFASGQFVLSVEVNPPRGLSVEKLLAGARLLA
AAGADVINVADSPMARMRMSPWAVCHLVQDEVGLETVLHFPTRGRNLLRVQGDLLAAHAT
GVRNIFVVMGDPTSIGDYPEATDNYDVVPSGLIKLIKHGFNAGVDHHGDEIGEATSFYVG
CALNLDTANVEQEIRVLRRKIEAGADFVLTQPVFEPQRIEQTISAFEERYGPLGIPVLVG
ILPLYGIKHARFLHNEVPGISIPEAIQKRVSAAGDRAPQAGVSMAIEIIDQLKDSVAGAY
LLPPFNRYDMAAEIIESVAEKMPAGGGV
>A0A6G1WJ00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium medicae|TrEMBL
MSPDINPYDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPHDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLSTPPHVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PLASAKTARWIRSNVPGIHIPDSIIRRLEGAQDQKKEGKQLCIDVMNEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLRGRKPWKREAAPTDAMVAERLEHIREGREENQQQMAEAAAH
HPHETKQ
>A0A535W8Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MEASTAPDRRAHPFLERLAQGPLLGDGAMGTQLHARGVSFERSFDELNLTEPKIVEEIHR
AYISAGAELIETNTFGANRIKLARHGLDTRVRDINFRAVKLAREAREISGEPVFIAGSVG
PIGQQLEPIGRIGIARATAAFEEQIAALLEGGADLLVLETFTNLPELLAAVSAARKTADL
PIVAQMTFAEDGLTLSAEEPSQVVQALERAGVDVIGVNCGVGPQVALQVLEAMRQQTRLP
LSGQPNAGLPARVEGRFFYFATPEYFATFARQAADLGVAYIGGCCGTTPAHIAAMRAALR
PVGATAPIPRRPASTAIPVDLSPAEQLPPTPFARRLADRAFVVSVEIDPPRGLNPSKCVA
GAHLVREAGADAVNIGDSPMARVRMSALSLALMIQAQVGIDTLIHFTSRDKNLMALQAEL
IGAHALGIRNIIALTGDPPRIGDYPSATGVWDVDSIGLIKILQRLNDGYDWLGTSIGRPA
SFTIACAVNPSAEDLDHEIDRFRQKIDAGAHVAMSQPLYDRRTLERFFERTGPLPIPFLL
GVLPLQSSRHAEFMHNEVPGIVVPEQLRERMRQAGENGIAEGLQQSRELLEDTRDLVQGV
YLMPSFGRYEVVAELVRWLRGRRVTTGAGTPGPAN
>A0A7W3X7L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. SR44-3|TrEMBL
MAFHHAQHAQSLNQSLSEVNGAINVSFEFFPPSTPEMEQLLWSSVRRLEPLKPKFVSVTY
GANSGVRDRTHSVIERIQQETQLVAAPHLTLVDASDEELVELAKQYWQSGIRDIVALRGD
LPAGQPKPTRFAVDLVRLLRSVADFDISVAAYPEGHPDARNAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVTNFTQLKRFAAMTNVSLPQWLHQQFS
GLEDDPATRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPKVAV
>A0A535P6U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
AGRDALVAGSVGPLGSPTHASDERDPARIRSAFREQIDGLLEGGADILWLETFSDLETLL
IATEEAQRAADLPVVTSLTFGEELSLLDGTTPDAAAGVLLAAGVDVVGVNCGVGPEACLD
ALERTGKPTLETSRSILPNAGLPQRIAGQFVYAAGPEYFGAVVPRMLAAGARLIGGCCGT
TPAHTAAMRTALDAIATADERRAKARADAATAVAPARPRSTLGGASPRASLVEAGGAAVG
EAPPPTGLLEKLREGRFVISVEIDPPRSIRIERTIEAARLLQAAGVDVVNVSDSAMARVR
MGAMAVAFGIQHDLDLECLVHFTTRDRNLMAIESELLGAHALGVRNIIALTGDPPRVGDY
PTGTGVWDVDSIGLIEILTRLNRGEDQAGSPIGQRAGFTIACALDPTAADQMTEWDRLER
KIEAGAHLIMTQPLYGMRQVEAMLTESRRRFGADGFPLPVLLGVLPLVSARHAEFLHNEV
PGITIPDEAREAMHAAGERGADVGLELAQHLLTEAAPAVQGTYLMPSFGRYEQNAELVRR
LRSELPTRQAGTTTEPGARAATRAAT
>A0A1G1CDG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium RIFOXYB12_FULL_65_16|TrEMBL
MSFLQSLRDGKFTIVVEFTPHGAAEVKHVASIAKGLPELNRKYADSGIVFSGVSLTQNPG
GNASYDHLASLAILAENGFPAELEVMPHVTGKDMNRDALCVLLKALMERGIRTVLAITGD
EPLAAQGVFEVDSIGVLEAVKEVGVSSLKSAKNAKEFSALPYLSAGAAVSPFKYTEGSLA
MQFIKAAKKIRSGATFLTCQSGWDSQRSELLVKEMGACGVPLIGNCLVVNTAAAKFMQTL
PGAVITDAFLAKLKGESSADNLVRAGQQMAMFRALGYGGIDLGKPGEFKSIDEIVKVVDT
ALACKDWRAVNANLHFPAAENAPPCNERVPHVSLLGHSMVFEKSGSLHGLAKAVFGPFES
SAAHEGFLYHLFEAQELWAKGLLYECEACGDCFLTENEYLCTKGGCEKGLPNPPCGDADP
KGRCGNNANRICVGERLYYRFLKCGKLDELKNMILPPRMAKLQDTASILNYFFGRDHMAP
PKLRTAPFIQIAEMLHASIPFPGAAMRHLQTLGPEGWTRPNRGLTAVEHLIRSQAQEGAY
FIDVNIDALNDPEAPTLMRRYVRLVQQISGGVPPCIDSSDGNVLVAGLEEWYSRGKAPAK
PMVNSIPFVEMDKRVPVYEMRKKYPFNVVCLLVGPEGPMRSADEMYDAAKVMFRKAREAG
FAPDEIYFDGVTLGMSTDGCIGGDGSNKPSHTHNSFHAIKRIKADPEMAGAHAILGVSNW
VYGAKKRRIGHLRAFVAVAQKYGLDGGIVDVSKALGVEPAVPELMDFVEMYVSLDGSEDS
MTRYVEKMQFMRDNDWV
>A0A536BVD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MASTISTERQRFHERLGRGPLLFDGAMGTLLFSRGIPQRACLDELVVTRPDLIGAIHREY
LEAGADAIETATFGANRIRLATYGLANEAGAFNRRGAQLAREARDVSGREALVGGSIGPL
GGPTHGTIHYPEQVIRDAFREQVEGLLEGGVDLFVIETFSELDHLLIAVDEARRASDIPV
IAELTFGEELQLTDGTTPEQAAAALLEAGVDALGVNCGVGPLACLEAVERTGPGDLVVAR
SIMPNAGLPQRVEGQFVYAAGPDYFGEMVPKMIAAGAAVIGGCCGTTPDHIRAMRSAVNV
ALAQTAADTARHEARARGLSSGTGGLTTGPRTAIAESATPHAVGEAPPPTPFLQKLMDGR
FVISVEIDPPRSIRIERTIEAGRLLKSAGVDCVNVSDSAMARVRMGAMAVAFGIQHDLDL
ECLVHFTTRDRNLMAIESELLGAHALGVRNIIALTGDPPRVGDFPTGTGVWDVDSIGLIE
ILTRLNRGEDQAGSPIGQQAGFTIACALDPTAADQKTEWERLERKIAAGAHLIMTQPLYD
ISQVETMDAEARKRFGQAGFPLPLLLGVLPLQSARHAEFLHNEVPGITIPEGSRAALHAA
GERGAEVGLEMAQSLLEQAESLVQGTYIMPSFGRYAQAAELARRMRDRQAARVSKATSAG
>A0A7C2K8R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNRAGPIDESAGSGRSRLERVLRSGRFAVTAELNPPDSADPQAVYDRALVLASVCDAINA
TDASGANVHMSSVGVCALLTRAGYEPVMQVSCRDRNRIAIQGDLLGAAAMGVRNVLCLTG
DGVQAGDQPEAKPVFDLDSITLLRTAATLRDEGRFLSGRPLEVAPKFFLGAAENPFVPPF
EERARRLAKKVAAGAEFIQTQFCFDVPRLEAFMRRVRDLGLDRSVAILVGVGPLRSARAA
EWIRTHVPGVVVPDEVVERLRGVPPPRQAEEGKQICIEIIRQLRAIDGVRGVHVMAYRQE
ELVAEIIERAGLLPRRVARDEPRTAAVGEGEA
>A0A2D9GQ73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNIXESNFKNKLTNNEFVITMEVSPPDEFDLQSFFPKFDFLSKTTIDALNITDTARAQGR
MSPLAISSLIQNQFDIETIMHIAVRHRNLLSLHSDLMGAHALGIKNIFSVMGDKPKKDSP
FFNSTFSNLTPNSALKLMXNFNKGISISGEKLKSSANFYKGAAFNPSTQNLEKEIQNLKX
KVESGADFLLTQPFYSTKTLQNILNIIGEFPIPLIIGVLPLRSIKNAQFLQNHVPGININ
SEIMSLMESSKSPIKTGMEISSNIVNQLKGKIAGMYYIPPFNNYKSILEFTKRLELPFSF
Q
>A0A3M1H0W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGDEGLKAGSQLERVLRAGRFAVTAEIGAPDSADPEAVYREARKLAGWVDAINATDASGA
NVHMSSVAICALLVRAGLEPVFQVSCRDRNRIAVQGDILGAAALGIRNVLCLTGDDVSVG
DQPQAKRVFDLDSVRLLRVAKIMRDRGMFLSGRKLETPPRLFLGAAANPFVPPYDWRPLR
LAKKAAAGADFIQTQYCFDVPRLRAFMGRVRDMGLHQTVYILVGVGPLRSEKAAEFMRTK
VPGVVIPDEIVDRLRKTPKAKKVEEGKQICLEIIEQVREIEGVAGVHIMAFRQEELVPEI
VAEAKLR
>A0A3C0K4L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAHLICIYQQLKCIRNFVLRIHNIIAGTRTISFEFFPPKDTSGMIGVLDKIKSLKSYSPD
FVSITYGAGGSTRRFSEELIMQAKAEHDLEVMAHLTCIGHSADELDAILRRWDKSGIDNI
IALRGDFPKDGFLNSNINSTFQHASDLIKFIDENYPFCIGAACYPECHPESISIEDDLSF
TKLKVENGAEFLITQLFYDNDDFYRFVERARSQGITVPIIPGVLPVLSAKQTRRFTSLCG
ARIPSNLAAKLNKYENDDKSARAMGVDYAIKQVESLWDYGVCGVHFYVLNRSYSVSKILD
SLKLDRQLI
>A0A535IBL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKARLKAAPRSRARSAVRHEHGPRPHAAPHSASIRWRCHHAMTKAAAIGGSPVAIGSRLR
RALDAGRSVITAELAVPATVAHKLILERAKGLLRPQIVAMNITDGLRGRPALSPIAAAAI
LTHADLGVEPIVQVVARSRARNSLIADLLGASALGVRNLLCMTGDVPESSGDIDDVDVFT
LIELARGFPAGLGTELLGTAEPFCVGAAWSPFAPDPAHEAERLVRKHAAGAVFVQTQPMF
DAHGFAAAIDRLPVSLTELPIIIGLAPIRSCDHAQRLGAIPGIVIPDRLLALLDRASDEA
DACERYWAYLDAELDWLTRNVPHRGFHLMPIGHSKRGIRQSSSFDRLYAAATRALDAAPP
NLAEVAAPVEVSGRVFRTSAV
>A0A0J7IJH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium angstadtii|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIEN
IMALRGDAMKGHQYFEPTQGGHASAMDLVHQINDLGRGKYLHNEDTVGEDLNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVTKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELITEVENAKNNEAVKQIGIEWSINQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A535S5K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLSPSRLAGLLRDGHFVVTAELSASNSADPEATWRRAEVLRGSVDAINCTDNTGAHVHIS
PLAAAHLLVEKGLEPIMQLTVRDRNRLALQADLLGAASLGVRNLVLMSGDDVTAGDHPEA
RRIYDIDSMQLLEVAAGMRDRGLYLSGRKLEQAPSFFIGAVENPFAPPLDFRPLRLQKKL
RAGADFIQTQLVFDVPIFARFMAMVADLGLLDKAFIIPSIGIPRSARGARYMKEKVPGLH
VPDALVDRLEKTAPARQADEGVQIAVELVRAVREIPGVAGVHLIGIKWEEGVVQVAEAAG
LLPRPTLSPLATVGGRG
>A0A535PTU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIAELLNRGRPTVSFEFMAPRDESEVELLERTVATLSGHAPDWVSVTYRLRTGEKTLEL
VTRIKRHYHIEAMAHLTCANNRDETRRILNWMEREGIANVLALRGDPPGPGEPFQPVDPA
LAHGSDLVKFVRGNGYRLGIGAACSTEKHPESPDLEQEFRYMRLKVDSGADFLITQLFFD
NRFYFDLVARARAEGIKVPIVPGLMPIPSRRSLAFVTQMSGASVPEVLQRAIDEQPDDEG
IRNIGVEHCIKQCAELLEAGVPGLHFYTFNRARAAIQILGALRGQQMLAS
>G7GPN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia amarae NBRC 15530|TrEMBL
MRGGHGYQASRPVRRTFRTVPYDVPVTTNSTSPSIVDRLSAPHRGRIPFSVEFMPPRDAE
GEERLWRAVRTFERLGPAFVSMTYGAGGSTRDRTVRITGQLAAETTLLPVAHLTAVNHSI
DELRSLVGAYAAQGITNILALRGDPPGDPLGEWVRHPRGLTYAEELVRLIRDLGDFHVGV
ASFPEGHHRAPDLRQDTQALVSKLRAGAEYSITQVFFDVEHYLRLRDRLAAADPEQAAKP
LIPGIMPITSLASVRKMVSLSGSVIPVDVEARLAAAAGTGDQEDRAAVRAVGIDLATEWA
ERLIAEGAPCLHFCSLNFAKASTEVLARLGVDVTAAVPATT
>A0A2E5F6N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MISHSIVALRGDPPKEEPEFMNAASEFQHAEDLVHHIAESNAFSIAVAGYPETHIEAPSL
QSDIRYLKQKVEAGADAIITQLFYDNNDYFKFVEACRDAAITVPIIPGLMPILDVNQIQR
ITSMCGAKIPPYLMQELLKTEGNPAATHRLGIEHTIAQAKELKANGVPGIHFYVLNQYFH
ISEIMTAI
>A0A661VQ28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKSDSNLEKVLSAGHFAVTAELGPPKNADPEVVRKKARMLKGCADAFNVTDGQTAVVRMA
SWAACLIQKEEGLDPIVQMTCRDRNRIALQMDVLGAAALGINNILCLSGDHMSFGNHPES
KGVYDIDSIQLVKMVKDMRDEKKFQCGEEMKVEPRLFIGAAANPFADPFDYRPYRLAKKV
AAGADFIQTQIVFNVPKFREYMKRVCDLGLHEKVYILAGVAPIKSSGAARYMASQVPGMD
VPQEFVDRMVAAIKGIPSPKSIADPEKKKEVRRRRREAWQAEGIKICAEIIQQVREIPGV
AGVHIMAIEWEEAVHEIVSQAGLLPRPTV
>A0A535AYV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
SPSTAIAIDLNPAEQLPPTSFAQRLADHAFVISVEIDPPRGLNPAKCIAGAQLVKESGAD
AVNIGDSPMARVRMSALSLAVMIQQQVSVDTLIHFTSRDKNLMALQAELIGAHALGIRNI
IALTGDPPRIGDYPSATGVWDVDSIGLIKILQRLNEGYDWLGTSIGKPANFTIACAVNPS
AEDLDREIDRFRQKIEAGAHVAMSQPLYDRQTLERFFERTGSLPIPFLLGVLPLQSFRHA
EFMHNEVPGIVIPAQLRERMRLAGENGIAEGLAQSRELLHDTKALVQGVYLMPSFGRYEV
VAELVRWLRQERAPTLPSSRA
>A0A535PAR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKRVTLADLLRTPRYEVLPTDDAADRVLAYVPKDVTITVTASPRRGMPATVHLALRLAQL
GYQAVPHLSARLIRDTHELGQILDALRPAGITNVFVVAGDAREPAGMFPDSLSLLAALPP
DHGLKEIGVTGYPESHPFIHDDVTIQAMWDKRLLATYIVSNMSFDPTTVTYWLERVRQRG
VELPIHIGMAGVADPIRLLKVSTKIGVADAARFLRGHPSWVARMFRPGGYEPGRFVTAML
PAMSSPALRVAGLHVFTFNEIEPTERWRREMLLRVA
>A0A359EI61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
DPEREIKLLRRKIANGANFALTQPVYQPEKAREFLDLYAKQFGDLEMPVLVGILPLYSVR
HAAFLHNEVPXDARFWAL
>F0YYN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. D5|TrEMBL
MKTTEIFKNHTVLSFEVFPPKRTGSVETIYSTLGELEKLHPDFISVTYGAGGSENCKATL
EIASAVKNDYHIESVAHLPCVGLSRADVLSQISLFGKAGIENILALRGDIPQGGECGSDF
RYASELIAFIRERCDFNIIAACYPEGHTESKSIVEDIRNLKTKVDAGADQLITQLFFDNN
YFYRFRERCSLAGIHVPIEAGIMPVVNKKQIERMVSLCGVHLPRKFTAMMERYEHNPEAM
RDAGIAYAADQIIDLTAQGVDGIHLYTMNNPYIAAKIYEAVHRVIAA
>A0A2W1BAJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTTADPTPKTDYRLRSKLERGEWLLSVELDPPHGLSAQAGLKAATALRDAGADCIDVGDS
PMASVRMSAVAFAARVQQQTGLEAVLHFASRDRNLMSLQSDLMGAHMLGLRSVIALSGDP
PSLGKYEGASAVWDVKAEGLIELIAMLNAGHDSAGNQIGGQAEFTIAAAANPNNPDLDAE
IARLQQKADAGTHVFFTQPTFDIAAVERFAERAASVGRPVVLGVMVLAHARNARFMAQNV
PGIAVSDAIIERLDAAGDGAAEVAVDLAQEFVEQVRPLSAGVYLIPTLGRLGGAIEVVRR
LRA
>A0A2M7PCP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_10_14_3_um_filter_51_14|TrEMBL
MSDYKAGSNLEKVLKAGKFAFTGECGPPQGANITKLKEKAAHLKGCVDAVNITDNQTAVV
RMSSWAASLTVLQEGVEPNFQMVCRDRNRLAAQSDVLGVYSHGIRNMLCLSGDHQKFGNH
PEAKNVFDIDSIQLINVVKTMRDEGKFMNGQEIDVPPKLFIGAASNPFAEPYEFRVFRLA
KKIAAGADFIQTQCIYNMVRFRDFMKRVVDMGLHEKCYILAGVTPMKSVGMAQYMAKQVP
GMDVPDSLIKRLKGAPKGKAAAEGIKMAVEQIQEFKEMPGVAGVHLMAIEWEHRVREIAE
LAGMLPRPVV
>A0A535I1L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLQRGRPTVSFEFMAPRDESEVEVLERTVAALAGHAPDWVSVTYRVRTGEKTLEL
VTRIKRHYHVEAMAHLTCANSTDRTRQILNWMEREGVANVLALRGDPPTSGEPFAPVDPE
LTHASDLISLVRRSGYRFGIGAACSTEKHPESPDLDHEFRYMQLKVASGADFLITQLFFD
NRFYFDLVARARGAGIKVPIVPGLMPVPSRRSLSVMTSMSGATVPVSLQGAIDAAQDDEA
IRVLGVQHCIAQCAELLEAGVPGLHFYTFNRARAPMEILAALRGQQLIAS
>A0A2P7YDM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elsinoe australis|TrEMBL
MHISPKLRQSAEERRPTFSFEFFPPKTAQGVQNLYDRMDRMHDFGPTFIDVTWGAGGNLS
HLTTEMVKVAQSVYGLETCMHLTCTDMPRSKIDDALRDAYNAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDHRDQELLIKHLKEKVDLGGTF
VVTQMFYDADIFVDWVKKCRAAGINVPIIPGIMPISTHAAFLRRANWTKCHVPEHWTKAL
EPVKNDDAAVREVGKGLIAEMCRKLLDNGIYHLHFYTMNLAQSSRMVLEELNILPCAESP
VEKPLPWRQSLGLKRREENVRPIFWRNRNRSYIARTQEWDEFPNGRWGDSRSPAYGELDA
YGIGLKGTNEQNRKIWGSPKKLRDIADLFARYIEGKVESLPWSESPITGEADVLRADLAN
LNRRGILTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELLTRIERDD
DVTYFAVNQDGELKTNSPSDAGPNALTWGVFPGKEIVQPTIVETVSFMAWKDEFYKLGRD
WSRCYDNDDPARYLVDGMMKEWYLVNIVHNDFRRERTIFPFFDGLEVPNLDEPAAIDDGY
LNGEKQHERSDSARINSHSTPNGDKTSESATIGEKTKEKASEPAPSSESWVGLGINPKN
>A0A1F4JI39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFCSPHIGHO2_12_FULL_65_48|TrEMBL
MIAANAQGTGFPVSFEFFPPKTPEGADKLRAARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVGAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPEADLNAYIAKVQAGADSAITQYFYNSD
AYFRFVEDTQRLGANVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSTATLEICRRLGI
>C6JEH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. 5_1_39BFAA|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A5W0X331|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Typhimurium var. 5-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A812UEG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiodinium microadriaticum|TrEMBL
MTTVSPKITEAIATKPADQIWISLEFFPPRTDKGVDTLYNVIGNKLKNLNPIFTDFTWGA
GGSTSDLTLDLCVQVKSRYGLNPNMHLTCTNMEKQKVINALAGCKTAGITNIVALRGDPP
AGQEAWEAVEGGFTCALDLVRFIKAEHGDTFCLSVAGYPEGHPNNMTAVDDVSSLSEAEL
GRMATFVEEDGTTVRSVCRDDAYEIELNYLKEKVDAGASTIITQLFFDNAVFLTFVRDCR
AKGITVPIIPGIMCISSKGGFKRMTKFCKTRVPKVLSMELDAAEDDEAAKAIGIRYGTEM
CRELIASGIDGLHFYTLNLRNVTVGIIDSLKESGVQLFTPGQQTVFDGLLGGSA
>A0A432Q8T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp|TrEMBL
MKSGSNLERVLKSGEFAVTGELGPPKNSDPEVVRKKARILKGNVDAVNITDCQTAIVRMS
SIGAGLIAQSEGVEPVIQMTCRDRNRISMQSDLLAASAMGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQMLGMVRDMRDAKKFQCGEEIKGSAPELFLGAAANPFAYPFEFRAVRMGKK
ISNGADFIQTQIIYNVEKFARFMEMARDLGLPEKAYILAGVTPPKSLGMARYMKKFVPGM
DVTDEVIDRMKGAKDKKQEGINICVDIINQVKEIKGVAGVHVMAIEWEEAVAEICESAGL
LPRPTFDEVASSTVELTPSVASDQAVEVRSRDAATDDVMNKAREEAASIVAAARLEAETI
LSGAKPVTTTTETAAIATDDAGEHEMNEKERQMALESVNQGLKALKSAYGLSDDQFEALL
NFASAEAVLKRDPAIGAHPSSAPVATAAAPAAAAKPAVDDAAKKAEEAAAAKAK
>A0A7U4QJ54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfofervidus auxilii|TrEMBL
MRVKDILNDTKISFSFEFFPPKTDTGWKQLFDTISELMLLKPSYVNVTYGAGGSTRDRTY
NLVTQIQRETGLTVVSHLSCIGSTKEEIRSILEKYNQSGVENILALRGDPPKGEKLSSLK
GDFKYAADLVAFIKKHFPHMSIGVGGYPEGHPETPNRLKEIEYLKAKVDAGADYIVTQLF
FDNRDFYDFCERCELVGIHVPIIAGILPITSYQGMIRMAELAAGSRLPAPLLKSVMRAES
DEYVEKIGIHWATEQVRDLVDHNVRGIHFYTLNNSRPIFKIYEYLGVRDSIQLSAQPGHI
IRRDTKVE
>A0A7C4EMJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfovibrio aggregans|TrEMBL
MTGFKKKLLNDQFVFTVELTPPRGSDTVTMIQKIEELKDLVDAVNFTDNPSAKMRMCSMA
ACKISLEKGLEPVLQMTCRDRNRIAIQSDLLGAHALGIRNLLLMTGDHPFLGDHKEAKPV
YDIDSSLLIRLVNNLNKGIDINGNRLNGKTSFFYGAVVNPNAEPIQPQLKRFEQKIRMGA
KFFYTQMIFEIEKLERVVEYAEKFKVKIVAGIVIIKTKRMLKYLSSKVPGVTVPHWLTDK
IEKLDDKDVQKFGFDFATSAIYKIMDRKLSHGIHIMAISVTEEVGKLLNFLKTGI
>A0A7Y3LPT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S3(2020)|TrEMBL
MALGIPSTRTDSAVSIRDLLARGGRSYSFEFMPPRSAAAEAGLWTAIRRLEALSPTFVSV
TYGAGGSTRGRTVNVTGRIAQETTLTPVAHLTAVDHSVSELRNILGHYADQGVRNVLALR
GDPPGDPLGPWTTHPQGVRYAAELVSLIKESGTFCVGVAAFPEMHPRSPDRDSDIRHFVD
KCRAGADYAITQMFFDVDDYLRLRDRVTAAGCETPIIPEIMPVTTIRSLRRIPTLSTAVF
PDRLAERMLAVQDDPRAVRALGIDHATEMCRRLLAEEAPGLHFMTMNFSTVTTEIYQNLD
LNG
>A0A2L1UUH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rahnella sp. ERMR1:05|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFLSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRQIAQDYWESGIRHIVALRGD
LPPGGGKPEMYATDLVHLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPNWMNSQFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPDIAVPV
RA
>A0A5C7L8J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinobacteraceae bacterium|TrEMBL
MNTHPVTFSFELFPPRTPEGTAKLPAVIARLAELRPEYFSVTYGAGGSDQDGTYETVMRV
VQQTGIEAAPHLTCVGSTREKIKLLLDRYRAAGIRRIVALRGDLPATALGAQAPGELHYA
NELVSFIRELHGDHFHLEVAAYPETHPQATSPAADFENFRRKVAAGADVAVSQYFYNADS
YFDFVERCGKAGLKIPVIAGIMPITNHAQLTRFSAACGAEIPRWVRLRLEQYQDDRQALL
DFGLDVVTRLCRTLLDNGCPGLHFYTLNQSEATLRLWKNLGLPVPVSSVA
>A0A417NQ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. TF06-23|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A138AVX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tsukamurella pseudospumae|TrEMBL
MTEQSRTVLDRLDAVRASGRMPFSVEFMPPRDEEGEARLWRAVRTFERMDPAFVSMTYGA
GGSTRDRTVRVTGEIAETTTLLPVAHLTAVNHSITELRALMGAYADRDVRNVLVLRGDPP
GDPLGRWVRHPQGLKYASEVVELVRELGDFHVGVASFPEGHHRSPDQESDIRYFANKLRA
GADYSITQMFFDVDDYLRLRDAVTAFDPEQGAKPLIPGIMPITSLKSVSRMAELSNAKIP
DAMRAELRAAAGDGPEENRAAVRAAGIEIATRMGERLIAEGAPALHFCTLNFAKATSEVL
ENLSMLPVGV
>A0A417BCH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM45-2|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNVLCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A1G6IBY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parafannyhessea umbonata|TrEMBL
MRIADILKSKQTFSYEIFPPKGDMSVVQATDVAERLMQNSPDWISVTFSAGGSGNSQNTV
SVAKAIQASGKTQALAHLTCLGSSRADVDAYVEKIKAAGVQNVLALRGDRAPGRDVIDFE
HASDLVAYLKQAGLCVGAACYPEGHLESSSPEADIEHLKAKVDAGADFLVTQLFFDNEDF
YRFRDRCSRAHIKVPIVCGIMPFTSVQQIQRMAFTCGASIPAAVIKRLVAAGDSKQAQQD
AGVAYACEQLVDLARNGVDGLHVYTMNRPSVANATHDRLLQAGYVEA
>A0A1M8A7J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malassezia sympodialis (strain ATCC 42132)|TrEMBL
MIPVVREPPSIYEKIRQAPDDANLWSLEFFPPKTVLGQANLCERIERMTKSLQPSWVHVT
WGTGGSTRDSSLELAARVQNGVFDPEEDVSLVTAPREGACDVCLHLTCTNVDPIYLDDAL
DRAKRFGIRNILALRGDAPRGEEYWVATDQRFQHAIDLIRYIRARHGDYFCIGMAGFPEG
LSRGTEADQKRELAFLKEKQDAGAQFIVTQLFYDVDLFVRWYHACRQAGITIPVIPGIMP
IQNYSSFLRIVNLCGATVPQHVLDLLEPIRMDDAKVKDMGIELSQGLIRSLRAQTDIHTF
HIYTLNLEKSATNVIKGVSDVPSPIPDMPGAETWDEFPNGRYTDARSPAFGEMDGYGASL
KLPPTQAVKLWGTPVDEEDISRMFTQYVSGQLPCVPWCDIPVWDETTQLLPMLLRLNMPK
AEGGKSWWTVGSQPAVDGCDSSDPVFGFGPQGGYIFQKAFVELFLTQEDKEALVAAIRAS
ERPVTYFAGTCDPASMETNVQKHGLNTVTWGVFPGKEVAQSTIIEEASFRAWRDEAFAIW
REWELLFPPRSATRSLLRSIHDQRWLVTVVHHDYKDPSGLWNLLDQVATAP
>A0A2E0HD23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium|TrEMBL
MNSQTKYEKSYSFEFFPPKTDKGVEKLQAVQAELAARKPAFFSVTYGAGGSTRDRTFATV
VRVKEGTGVSTAPHLSCVGDTKAQLGELLQQYKDQGIDQLVALRGDLPSGMGASLGELKY
ASDLVAFIREQTGDHFHLEVAAYPEKHPQAKSMAADLQAFKTKVQAGASSAITQYFFNVD
AYKFFVDSCEKLNLDLPIVPGIMPITNYENLVRFSGMCGAEIPRWIRVRMEEFQGDHDSI
RQLGEEIITNLCAELLEMGAPGLHFYTLNQAEPTLAIWDNLGL
>A0A1N6X029|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Domibacillus enclensis|TrEMBL
MTLLDKLKTDVLTADGAMGTLLYSYGIDFCYEELNTEKPEIIEKIHHDYIKAGADVIQTN
TYGANTLKLSRYGIENRVRELNEAAVQIAKKAAAPGGQFVLGTIGGVRGIRKSTATNEEI
LASVKEQAESLLSGDPDGLLLETYYDFEELSASVKLLRQMSDVPIIAQVSMHEPGVLQNG
LSLNDALQQLEGIGANVVGVNCRLGPYHTIQAFEDVKLPNKAFLSAYPNASLLDVEDGRI
VYESEADYFGRAAVLLRNEGVRLIGGCCGTTPKHIEAAKKRLAGLPPLTEKKVKTKKPIV
IQEAAPATDQSICEKAKTERTVIVELDTPKTLMTERFIEGANALYNTGIDAVTMADNSLA
SPRISNMAMGATLKMNHDVRSLVHITCRDRNLIGLQSHLMGLDALGLHDVLAITGDPTKV
GDFPGATSVYDVSSLELIQLIKQLNEGISFSGKPLKKKANFSVAAAFNPNVRVLDRAVQR
LEKKIEHGADYFITQPVFTKEKIIDVYEATKHLSTPIFLGIMPLTNMRNAEFLHHEVPGI
KLSDETLERMRACGEDKEASAKEGVKIAKELIDTAAGLFKGLYIITPFLRYDMSIELIHY
IKELDAQKESGALHDHSSN
>A0A1C5QKH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKINELLKKRPTLSFEIFPPKNNENDITSIYATIDELAKMNPDFISVTYGANGSTSKNTC
KIASTIKNKYGIESVAHLTCMNNTKDEIKEILEELKENGIENVLSLRGDYPKDGDGINHG
DFKYASELNEFIEENFPNDFCLSGGCYPETHYEAKNFEEDLLNLKKKVDAGAKYLVTQIF
YDNQYYYRLVREARKIGIHAPILAGIMPAHNPKQLKNIAKMSNCSVPFDLAAMIDRFAGN
PKAGREVGLHYATYQIIDLMTHGVDGIHIYTMNKPEIAKEILKRTEYIRDEFFKD
>A0A7K8EIC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucopsar rothschildi|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITRHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDVCVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYEQRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6L9U5C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium lusitanum|TrEMBL
MAHIDENPLGVHLPLDPLPGHYSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFRDYMKKVRDLGLTEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDAVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRTDALVAERLHQISEGREENQQAMAEIAA
HHTPQQAH
>A0A7C9GSQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus khanii|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSIGRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWNNGIRHIVALRGD
LPDNSEKPKMYGADLVELLKKEADFDISVAAYPEVHPEAKNSQADLICLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIEVEIVPGILPVSNFRQLKRFATMTNVRIPSWMTRMFQ
GLDDDPESSNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A2M7CSN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium CG02_land_8_20_14_3_00_62_12|TrEMBL
MKISLEFFPPKTDEQHAVLARALPKLQAVNPEYVSVTFGAGGSTLSYTPETVRVLKQTWG
FDAAPHISCMGGSREEIRQLLKLYQAMGCKRLVALRGDMPSGMAGFGDFRYANELVEFIR
AETGTEFHIQVGCYPETHPQAGDAFADLKNLKRKIDAGADGAITQYFFNTDAYFRFVDDA
RRFGIAQAIIPGIMPISNFAQLKRFSEVCGAEIPRWIDQRMRGLGDDGDAIRELGADLVA
ALCRRLIAGGAPALHFYTLNRAKATLNVIERLR
>A0A0M4TYL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc piscinale CENA21|TrEMBL
MEDNHSCTALNYFRKAAQAGEFLVTAEVAPPKGGNPTHMIEMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQNGVEPICQMACRDRNRIALQADLMGAHALGIRNILALTGDPVKA
GDHPDAKGVFDLEAVRLLQLIQKINQGFDCNDKPLTDGATNLFVGAAVDPQCGSWSGLQS
RFERKIAAGAQFFQSQLITDFERLEKFMDKIASVHNKPILAGIFLLKSAKNAQFINRCVP
GVNIPEHIIDRLAKAKDPLEEGVKIAAEQVQTARQLCHGVHIMAVKREDLIPKILDLAGI
APVNLVVAK
>A0A0Q6EDQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas sp. Leaf460|TrEMBL
MARRAPSSGKDIRVSFEFFPPKSDKMEETLWAAIERLAPLSPSFVSVTYGAGGSTRERTH
HTVSRILKETDLAPAAHLTCVDASREEVDAVVRQYRDTGVRHFVALRGDSQAGAGAAYVA
HPGGYRNAVELAAGLRAIDDFEISVSAYPEKHPESADFATDIDLLKRKVDNGATRAITQF
FFDNDLYERYVERVRKAGIYIPIVPGIVPIHDFVKVARFSAATGATIPTWLAERFEGLEN
DAQTRSHVAAAVCAEQVLDLVERGVDDFHFYTMNRADLVYSICHILGLRPKTGEPAASVA
GAGTAAAA
>A0A124HPB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces corchorusii|TrEMBL
MDPALLDDFSLEMTGKDVPGLEEARDSIPPGTRINITFLAGEDTGTRLTAARAVKRLGFV
PVPHISARRLPSRTALEEFLAGLAADGTAGNVFVVGGDPARPEGPYEDALAVLRTGLLRR
HGVRHVGIAGYPEGHPGIADRLLWPALTDKAAAIGADRFTGDVITQFGFDADPVLAWLEA
LRARGVHLPVRVGVPGPAGVRRLLRYAGRFGVGTSASVARKYGFSLTNLMGTAGPDRFLH
ALSDRYDPARHGTVKVHFYTFGGLRTTADWIARFRHGSERVSEERQTTRS
>A0A6J6DF29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARIADLLAAGRTFSFEFSPPKSAAASMSLGRTIAELEPLGPSFVSVTYGAGGSTREHTR
DTVLWVQRETNVPPMAHLTCVGHTRAEIEDIIATYVEAGIVNVLALAGDAPKDPADARPS
DYTYATDLIEHLREISDLSIGVAAHPEGHPRSPDLATDRRYLAEKLRMSDFATTQFFFDI
EHYLSLVNDLADLGVTKPVVPGIMPVTNIGQVERMAELSGAAFPSWLRERLESGRTPEDV
RRIGVDAATELCAALLEAGAPGLHFYTMNKSTATRDIYTQLGLPVA
>A0A6J7H822|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MAVVSRPDAGLPRAGRAQLAAALRDATYEVLPFKSAEDKVLADVPTDVALTVTTTEAKGL
GPTVDLAVRLTAAGYRAAPHLAARLVRDRAHLADLVAQLREAGVDRVFVIGGDAAEPAGD
FTDALGLLEALDEMGRPFSTVGIGGYPEGHGSIADEHIERALEAKAEHATQVITQLCFDA
ATTVRWARTAYERGVTLPVRVGIPGAISRQKLIRVSAGLGLGQSARFLKKQQNMFWRFFL
PGGYSPDKLIQQLTPAFGVPGSGLEGLHVFTFNELDTTEAWRQRWLARLP
>A0A2A8DQJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTSKFIEQGIRLLGGCCGTTPEHIESMKRATLNITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGILISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6J6EIS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTRQMTVPVSFEVYPPRSPEKLPGLKESIRVLDSVSPDFISVTFGAGGSSTRDSLEVLRF
IRDESSATPLAHLTCVGTTRQEASELVVSFLAEGITHFLALRGDLPEGALEHRGELHNAV
DLVTLMHELPDMPKPLERIAVAAFPNGHPESDSLDHDVETLLRKQEAGATLAITQLFFFT
EDYLTFVGKAHGAGITIPILPGLMPVVSPSRLNRVVELSGENRPAELSEALSSTEDAAAR
EAIGVDWTAKMVRELVDAGAPGIHLYAFNQHRTVLSVLEQSGVR
>A0A6J6ATX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVVRTSYSFEFFPPKDVEGEERLWAAIDGLKSITPDFVSVTYGAGGSTRDRSIRIAQEIT
KRTGISTVAHLTCVGSTRDELIAILHSYKEAGITSILALRGDPTGGPSAPWTPTPGGLNH
ADELVQLADEFGGFTIGVAAFPDGHPASYGDFEKDIDVLIRKEELGATFATTQFFFEADR
YTRLVDRLAERGSKLVIIPGILPVTNVKLLHRMAELGGTPIPSQIAEAFAKVESDPVAVR
ALGVEIATSLCQQLLSAGASGLHFYTMNSSTATQEIYGNLNA
>A0A6J7B3U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRSLKSDGSKALTYSFEFFPPKDVEGEERLWAAMSQLESIAPDFISVTYGAGGSTRDRTI
RITSEITARTHIPTVAHLTCVGSSRAELLEILGKYRDAGIKSILALRGDPTGGPRAPWSA
THDGLNHADELVTLAAEFGGFTIGVAAFPDGHPSSRGDFNKDVEVLLEKEKRGATFATTQ
FFFSADKWKSLIDKLAAKGSSMPIIPGILPVTNVKQLNRMAELSGVPIPGHISDSFIKFE
SNPDDVRKLGVEIATELCNDLLEAGAPGLHFYTMNTSSATREIYSHIKDER
>A0A8J7UFV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tidjanibacter sp|TrEMBL
MRIIDIIDQNISAGSCQFTFEVLPPLKGEGTSRIFSAIDTLAPLGPAYINVTNQREAVKT
EFDAEGNPRRRVYRHRPGTVGISAAIAKRYKIEVVPHIICGGHSRYQIEDLLIDLDFLGM
HNVLALRGDGMKDERGFIPHPEGYAHADELVGQIVAMNSGRFIDNEVEDCHRSKFCIGVA
GYPEKHKESPDMESDIARLKAKVDAGGEYVVTQMFYDNSKFFDFVRRCREAGIKVPIIPG
IKPLSTTAQLDVLPKVFSIEIPEELERAARKCKDSDAVKQVGIEWATMQAAELKRAGLPI
IHFYTMGRTENVARIVKNVF
>A0A4U3B6W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYGATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGILISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6J7RN67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSPIRTAPSLGAVLAGGGHSFSFELFPPKTDAGEQALWQTVRELEALKPTFVSVTYGAGG
STQDRTVRITKQIAEHTTLLPVAHLTCVDASVDDLRRVIAQYSDAGVNTIMALRGDPIAG
PESRWVQHPGGLQHADELVALVRSLGAFSVGVAAFPEGHPESGDFEEDARVLAAKQDAGA
EFAITQFFFRAEDYERLVTRAAAHGCTMPIVPGLMPVTNVAQIERFAVLSGAQFPSELAD
KFGKIKDDQSAVHELGVEVAADLGGKLLAMGAPGLHFYTLNRSTSTREVYEALGLNEV
>Q8PZQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRFSASLEDASQLKGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDYPTCGDHPGSKP
VYDVDSVQLIELVRKLDTGVDFAGNKLDGGTSFCAGAVSGIDPEKTMQLIKLQKKVKCGA
DFIQTQAVYDIGMFEEFMDAVNYLEVPVIAGLIPLKSLGMAEFMNKNISGIHVPEEIMLR
MKDASSPMEEGLLIASETIKELTKLSRGIHVMPIGSHRNTARLLSLAGISQK
>A0A2N2BZ70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-21|TrEMBL
MSISSLFTHKSPVVSFEIFPPKRDGSLVNLNETIRSLATLKPGYISVTFGAGGNGVNAST
WEIARSIKDDFGIEPLVHLTCISHSKEDIDEILLRLKAYGLKNILALRGDINPDNPPKKD
FTYAGDLVNYIHTQGDFIVSAACYPEGHPESESLVQDTLNLKKKVESGATHLISQLFFDN
NLFYSFLDRAKLAGIAVPIDAGIMPVVNKKQIERMVTLCGASLPPKFKRIIDKYEDKPEA
LTDAGIAYAIDQIIDLISQGVDGVHLYIMNNPVIAERIYSGFSSLLK
>A0A443SAI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrombidium deliense|TrEMBL
MVRSRSSSDCSSSPNSHESSCEEYQRSDSSNSNSYNSKAVNFVRLHEKINERIDSKDIFF
SLEYFPPRTPEGGVNLISRFDRMREGGPLFCDITWHPAGNPGSDTETSSITIAGVALNYC
GLETMLHLTCVNMSSKELNKHLQRAKELGIRNILALRGDLPENEELVEREFEYASDLVRY
IRQQYGNYFTICVAGYPTKHPEAESYEEDIRHLKEKVDAGADFIITQLFFESETYIKFEK
DCRSIGIKVPIIAGIMPIQSHDSLRHIVRLSRLEVPEDILKTIEPIANNDEAIRNFGIHY
ATKMCREILAKNCSPGLHFYTLNREVATIEILKNLGLWKKNPQKPLPWLPVPNYKRCTEE
VRPIFWSNRTKSYVFRTSQWDEFPNGRWGDSASPAFGELKDYYLFIGKNKSSVEQLRKMW
GKELNSEEDIWNVFYCYLSQNANKNGIKVKKTPWNDGELNSETSLIADKLAEINLKGFLT
INSQPNINGAESSDKTFGWGAPGGFVYQKAYLEFFTSRKNALVLKDILQKYPHVNYDMIN
SNGTENYTNSCRERPMAVTWGVFPGQEIMQPTVVDPVSFKVWKDEAFSLWKESWGKLYAE
GTKSKQLINFVVENYFLVNLVDNNYPKECCLWKILDEVHSNVTANNDFMSIN
>A0A3A5Z5X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AF20-13LB|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSIIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIREVAKQIY
>A0A2G6M800|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus propionicus|TrEMBL
MDITALFQQKKVFSFEVFPPKKTSSITTIYNTLEQLSDLQPDFISVTYGAGGNTADNRTC
EIASAIQHKYQTKALAHLTCINARKTDVDTILSQLQDNGISSVLALRGDINPEQPHKEVF
NHASELVAHIKARGGFSISAACYPEGHLEAENMISDIHHLKEKVDAGAEHLISQLFFDNS
LFYAFIEKVRIAGISVPIEAGIMPVVNKKQIERMVSLCGVSLPAKFSKTMQRFEHNPEAL
RDAGIAYAVNQIIDLVANGVDGIHLYTMNNPYIARKITESVKNILP
>A0A1G0EP65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium RIFCSPHIGHO2_02_FULL_57_16|TrEMBL
MSKQLFSFEFFPPHTPEGVEKLAAVRKQLAALHPEFFSVTFGAGGSTQDRTIETIRQIKA
EGYNAAPHISCVASRRENIRAMLDIYRDMGIRRIVALRGDLPSGMGSLGEFQYANELVAF
IREQTGDHFHIEVAAYPEFHPQAKSAREDILNFKRKMAAGADSAITQYFYNADSYFYFVD
ECRKLGITVPIVPGIMPIVKFAQLARFSDACGAEIPRWMRRILEGFGEDNESVQAFGLDV
VAQLCEKLLAGGAPGLHFYTLNQAAPTLAIWKRLGL
>H0FB62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter arsenitoxydans SY8|TrEMBL
MSETNSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LSNLGCDAAPHLSCVGASRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQASSPSADLDHFVNKVKAGADAAITQYFFNADAYF
DFVDRARAKGVDVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GIDVVTELCQTLLDNGAPGVHFYTLNHAEAPLAIWKELSA
>A0A373UUK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF21-11|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKKHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A1Q8KTP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. Ae707_Ps1|TrEMBL
MRQTGEDGRVRDVRLDPCPKRMEFGPCGGVRADLTCELGTVPCPFTGGAAVPWTGPPGRS
AAPAAFGHEGPVVLTDLTSPPYDPAALGRIVRTIAGSCDALLIGQHHDEPDFPPTMLAVL
AREAGGHPWVTLTCRDRNRVVLEQDVAGLAAAGAEAVFCVTGDARGPSVRPDVSQVFDLD
GTRLASLAAAAGLPAVVPEAPDAPPTGLRPARLAEKQRAGAGAVVLNHAASPGRVAEFVT
AARGRGATLPVVAGVAVFTDEPGARRLEAFPGLEIDPAAVERVLTASDPVEAGIEAAVDE
AVALLAVDGVAGVNLSGRGSFGDDDTAAAIKAEIGHRIRSRAGTRG
>A0A202DBY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium B17|TrEMBL
MSDKELKSDSKLEQALASGKFAITGELGPPKSADAAEVKENAEHLKDVVHAANITDNQTA
IVRMSSFAAAVLAMESGVEPVMQITCRDRNRLAIQSDVLGAYALGIRNILCLTGDHQCFG
NHPTSKNVYDMDSIQLISMLKKMRDEKQFDCGDEIRNTKKAPVVEPKIFIGAAANPFGDP
IKFRAIRLAKKINAGADFIQTQCIYDMPRFKEWMKEVSEMGLHEKTYILAGITPLKSARM
AEYMRDSVAGLTVPDEIVKRLKDADDPKAEGQKMAVEQIQEIREIPGVSGVHVMAIGAEE
TVPGLLKDANLSI
>L0A584|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus peraridilitoris (strain DSM 19664 / LMG 22246 / CIP 109416 / KR-200)|TrEMBL
MSLSKNLGRSFVVTAELDPPRGPDPTSTLNEARALRGLVDAVNVSDSPMANLRMSPIAIA
HLIQRDLSLEVIFHLTCRDRNVLGLQAELLGAHALGVRHILCLYGDPPTRGDHPEATGVY
EVGADGLASMASELNAGRSKAGRELGSCTDFRIGVALNPTNPDLEREKERLQQKVSAGAH
FAQTQPVFSTEQVERFMDAVGELPIPVLFGVLPIRSVKMAQNVSKWASVPAELLSAVEEG
GAAAGVAWSAKLVEDLRGLGVAGVHLYPLGKPEIVGRVLGETPALTAG
>A0A844HBB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella parvula|TrEMBL
MTLREKHQQEQFTITVELDPPKSSSAEKTFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDAPTNFYIGATGNPGALDLEIERQKLAAKIQNGA
HFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
MEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLYIIDHL
>A0A1W5DTD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia proteamaculans|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGGGKPEMYATDLVTLLKDVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVVTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAVA
>A0A7W5JY71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microlunatus antarcticus|TrEMBL
MPGPSVVAARPRSVRRARKPTVAQLLEAAERPLVSFELFPAKDDEQHRQLWTTIRELESL
GPDFVSVTYGASGSTRDRTVSATQQIAEQTTLRPMAHLTAASQSRDELRHVVGAYASVGI
NHVMAIRGDMPGGPTMPWEPHPDGLRNATELVSLVAELGDFCIGVGAFPDLHPQTRDADL
DARILVAKQRAGASFAITQLFFTAQRYFDLVDRVRALGSDLPIIPGIMPVTRISQIERFA
DLSGAPLPSFVTDRLREVGDDPVRVRGAGVDLATTLSEELLAGGAPGLHFITMNRSPATR
EIYARLGPLLNRA
>A0A442S6E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQRDENPAGIDLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIASGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A529HWR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
FMQKARDLGHTEKVFILCGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGK
QLCIDIINEVKEIPGVAGVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAER
LDHILHDEITETQVDMVKTAH
>A0A529TQK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGI
>A0A1N7A217|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aromatoleum tolulyticum|TrEMBL
MAKPEISIEFFPPQTPDGEDKLRATRDKLARLKPAFFSVTYGAGGSTRERTFAAVKEIAA
LGFEAAPHLSCIGSTRDGIREILADYSAAGIRRIVALRGDLPSGVGDPGEFRYANELVEF
IRTETGDRFHIEVAAYPEWHPQARSPQDDLRAFKRKADAGANSAITQYFYNADAYLHFVD
AVRALGIDIPIVPGIMPIASFSKLARFSDACGAEIPRWMRRKFESYGDDADSIRAFGLDV
VTALCERLLAAGAPGLHFYSMNQAGLTTAICERLRLV
>A0A439IJM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRELGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVCG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A440EBD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEVRLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVRRILNETTLTPAAHMTCVDAARHQVDAVISEFAEMGVTRFVALRGDPAAGVGT
AYRPHPEGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHESEAA
GSAAA
>A0A2E9RBU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MSGTQKDTPEMRTMGKLAEALNSSSFVVTSELTPPKGTDLDELFAKADLLRDLVTAFNLT
ESHAARMAMDPVAVGHLLIDRGIEPIVQMTSRDKNRLAIQASILGAAALGVSNVVFMGGD
PPKNGDHPDAKPVFDLFASQLLEAACALNSGTDFSGNALKGAPHLTIGAVANPGASDLAG
EIDNMKRKADAGAEFFQTQAIYDVDAFDQFMNKAKPGKPVLAGIIPIKSVKMAQYMNDKI
PGVDIPQELIDKIDAAGDDKAKVADISIEIAGSTVRALRDMTCGVHVMAIGWEDKIPAIL
DRASD
>A0A1V5ITI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium ADurb.BinA094|TrEMBL
MSAGGVPTVVAPAALSLLLQEPRYEVIPARGIEQKTAVLPAGTTVTVTASPSLGLDRTLE
ASVALAARGLRVVPHFSARMVAGRDHLRRLVDRLEGTDIREVFVVGGDADPPAGDFVDAG
DLLEELAAMTHPFTRIGIGGYPEGHPLIPDDKLLAALKRKQPYATHLVTQLCFDAGALAR
WVGAIRAEGIELPVVVGLPGVVERRKLAEISLKAGVGASLSYLRKHGRQLVTLARSRRYD
PTGLAREVAEYAADGSLDIRGAHLFTFNQVEPTLDWVQRLS
>A0A529FV28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
GIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFEGLQNDPQTHALVASAVAAEQV
LDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHEAEAAGSAA
>A0A2G4RB42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter pomorum|TrEMBL
MSLSRLSVELIPRSAEALAADVATVKATFPVADTLNIPDLMRFPLRSWDAAALVHPQFGN
VIPHIRAIDIAPNAPLPGVDQPGLEEILVVHGDPPADLSHRTYPNSTESIIRRYRQEAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDMKLFDLCREWLQNECVFWGLS
PVIGPKSRSYWETTNHVVFPHDFSPTLEANIQFAQTVLKELAQEKGKAYLMPVRIKLEHY
LPALRDAVA
>A0A4U9Y3V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus anginosus|TrEMBL
MFIQSPSLSFEVFPPNPAVGNEKIMAVLKEMQDLAPHFISVTASNNKFNIEETTVRLADF
IRNDLHIPTIAHLPAVYLTKEMVSDTLEALDRVGVHKVLALRGDIFPNMEPKKDFTYATD
LIEYIKEQAPHFEIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYD
FQDKCILAGIEVPIYAGIMPILNRNQVLRLLRTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSDTAHRIYQATHTFFDK
>A0A5N0KRA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas cyclobalanopsidis|TrEMBL
MPAGTVQGARAFIDACSLEVSAKAMPALRAEAGRIAPGTTISIPYLASEDDEARLAAART
VRELGLQPMPHLSARRIGSHAALEHFITRAVGEAGVEQCLLIAGDLATPAGPFADSTAII
ETGLLERAGIKVVAVGGHPEGHPVMDAAGRWQALERKCQAIEARGMVPRIITQFAFDADL
VLAWLDALRARGIGHPVLVGVPGPASVTRLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPDVFVDRLVAGLTDTHGQVSPHLFPFGGIAPSLDWVAQYRLRQR
>A0A412PM21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus anginosus|TrEMBL
MSIQSPSLSFEVFPPNPAVGNENIMVALKEMQDLAPHFISVTASNNKFNIEETTVRLADF
ICNGLHIPTIAHLSAVYLTKEMVTETLTVLDKIGVHKVLALRGDILRDVEPQKDFVYATD
LIEYIKKEAPHFEIIGACYLEGHPDSPDRVSNIKNLKKKVDAGCSSLVTQLFFDNERFYD
FQERCTLAGIEVPIHAGIIPILNRNQVLRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSSTAHQIYQATHTFFNNKVSS
>A0A444BQB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycicoccus flavus|TrEMBL
MSNELPTVALARLVEGARYEVMPTPTIVDKVRTHVPASVPITVTAAPGKGLEATLWTSVE
LAGAGYTVVPHLAARMVSGRAELAEVVARLAEAGVTQVFVPGGDADPPAGDYTSALDLLR
DLDTLEHPFTHVGITGYPESHPSIDDDVTVQSMWDKRTYATHIVSNMTFDAEGLGTWCER
VRRRGVGLPLLVGVPGPVDRAKLLGMAGKIGVGESLRFLRKQKSVFARIAAPGFSTDKFV
SRVGALSANPALRIEGLHVFTFNQVEAMEAWRARMLDEARTARVRPVG
>A0A4R4HG71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. 204|TrEMBL
MTSIRFELMPLVGMQEAALSLPAGATVTVTCSPRHGLERTLEATEWLVDRGFCVVPHLAA
RRVRDSAHLESLLERLVALGVDDIFVVGGDGESPLGDYSHGLALLQAMEGLAQRPARVGV
PVYPEGHHAIDGDALERDLVAKASLADYAVTQLCFEAEPLLAWRRRQSRLGLALPVYAGI
PGVMEPKRLLAIAMRLGLGPSMRALRRQSGWLRRLLSPSDFRPDALLEKVEPLLGDGVDG
FIGLHVYTFNRVEPTQRWLEARLRLMAGRPESTSSVADPVTSAGEPLG
>A0A562C6X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. J18|TrEMBL
MSQFRLSRRPDIGGRIGVSFEFFPPKSDDMERRLWETVTRLAPLKPRFVSVTYGAGGSTR
ERTARTVRRILQETSLTPAAHLTCVDADRESVDGVIAEFVAMGVRRFVALRGDPREGVGA
RYRPHPQGYTNGAELTAALKARGDFDISVSAYPEKHPESSDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFAQVANFAGRCGAHVPVWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVDDFHFYTMNRADLVFAICHMIGIRAASEAEM
RPAAA
>A0A528FHG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFIQVANFSSRCGALVPAWLAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A353IKW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloceanibacter sp|TrEMBL
MPATQHSQGQEPPKRRFLGRGAIDVSFEFFPPRTPAMEDTLWRSIRRLEPLRPKYVSVTY
GAGGSTRERTHATVARLLSETTLKPAAHLTCVSATKDDVDEIIREYWDLGVRHLVALRGD
PPEGAGSKYTPTPGGYVNAADLTAGIKKIAPFEISVGCYPEKHPESPSVEADIDMLKAKV
DAGATGAITQFFFDNDVYFRYLDRVRAAGIDIPIIPGLVPIHNFKQAASFAQRSGASVPD
WLGRRFEGLEEDQETRHLVAAAVAAEQVLGLVDQGITEFHFYTLNRADLVYAICHLLGLR
PAKAFSQKAAEGTEPTKIAKVAS
>A0A562C7F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. J18|TrEMBL
MAPQSVHGYAADQQAVSNGEASLAQLLAGYSVEVTARDVDSVLGRLRRGSEVFIANLPND
SPDVLVRAAARVGAAGLIPVPHIVARKIRDEPELDGLLARLAGEAGVERALVLGGDRDRP
AGDFDAALQLLHTRAFERHNFSRIAFACYPEGHPHIDKEVLRQALREKLAEATSRGLDTL
LVSQFTFEPEPILKLARDLRASGITAPLRIGVAGSARRTTLVKYAIRCGVGASLRALTER
GHLVSGLIGGETPGELLEGIAPAAATEPALGIEGVHFFTFGEPGRSIEWAEAQINRS
>A0A5C6VXL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia azotifigens|TrEMBL
MNPIELSFEFFPPKTQEGLEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMSK
DGLEAAPHLSCIGSSKDSLRAILNEYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFCIEVAAYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DAHKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTNLCRRLVDAKVPGLHFYTLNGAAATKSICERLGV
>A0A512AIT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sediminis|TrEMBL
MTTTFDQLREARTALDTPLFAGLPGDIRVSFEFFPPRTDPLMEQLWDVVTTLAPLRPNFV
SVTYGAGGSTRDRTHGTVARIIKEARLPAAAHLTCVEASKAEIREVAESYWEAGVRHIVA
LRGDMGAPGVPFSPHPEGYANAAELVAGLKQIAPFEISVAAYPESHPDSPSVEADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDRLAAAGITAPVLPGILPVSNVAQTRKFAAACGAH
IPAWMDGLFEGLDHHPASRQLVAATVCAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPERAPLEQAA
>A0A1L9NAA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus tubingensis (strain CBS 134.48)|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A6I7Q2J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiaceae bacterium|TrEMBL
MTASGSTHPVFSFELFPPKTAEGMDKLKDEVARLQTLGPRYFSCTYGAGGSTRERTFETV
TWLRQQGIETAPHLACIGSDAAEIRGIVTHYLEQGITRLVALRGDLPSGMGHTGNGTFRY
ANELVAFLRKEFGDHLHLEVAAYPEFHPQAPSAAADLANFKRKVEAGADAAITQYFYNPD
GYFALVEECERLGLDLPIVPGIMPITNYTQLARFSDACGAEIPRWIRRRLEGFGDDRAAI
RAFGHEVVLDLCDRLLAGGAPGLHFYTMNQATPTMRLWQDLRLPVPA
>A0A6M5UL22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulosimicrobium sp. BI34T|TrEMBL
MPPRRPDAAPKFWETARRLVATHPDFVSVTYGAAGTDRATARQVVGRLLQGTPVLPIAHL
TCVGASREDVEEVINDFLDEGVRSFLALRGDPPRDQPDWQPAPDGVRSSTELVALLREVE
ASRCAADPAAALRGAARPLTIAVATFCDGNPAAGTTRSQEVRRLWQKQQAGASFAITQLF
YDASSYTDFVAEARAAGVTIPILAGLLPTTEPARLRRVEELTGVRAPQHLLDALDALPDP
EAQHAYGIAYTVDLAQRVLDAGTPGLHVYTFNKHRAALDLLEGVHLGGGSGGTGGSASAA
AAPLVPDLASGPWVTGTSLPTTSAATHGTPV
>A0A1Q6XE70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriales bacterium 13_2_20CM_55_8|TrEMBL
MAGDLLARLKKSPVLCDGAMGTLLYAKGIFINRCYDELNVSQPDLIRGLHHEYLQAGAEI
IETNTFGGNSFRLARHSMEDRVREINLAGARLGREAAKSFDVWVAGSVGPLGIRIEPLGK
TSYEEARDAFREQIAALIEGGVNLLVLETFGYLEELHQAILAAREVNPTIPIVAQVTIDE
DGNCLDGSVPETFTPRLEEWGADVIGCNCSVGPVAMLDAIERVRAVTSLPLSAQPNAGIP
RSVEGRNIYLCSPEYMASYARKFVAAGVRLVGGCCGSTPEHIRVMKAALRASEARSKVVA
ASASGAVATPLPSPALPLDKRSTIGAKLAAGDFLTMVEIVPPKGTDIRKELEGARFLKSV
GVDGINIPDSPRASARMSNQALSLLVQQQVGIEAVLHYTCRDRNVLCIQSDLLGAAATGI
RNLICITGDPPKMGNYPDATAVFDVDAIGLVNIVQNLNRGLDIGGNPIGVGTSFVIGVGA
NPGVPNLDEEIRRFEYKVEAGAEYAVTQPVFDLSLLETFLRHIEHCRIPVVAGIWPLVSV
RNAEFMKNELRVSVPNSVLDRMAQAKTPEAAREEGIAIAREMLVAVRDMVQGAQISAPLG
RYASAVDVLEALGSSRPATA
>A0A810L9G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinocatenispora sera|TrEMBL
MPGGDPAIGRLVRVAAPTFSFEFFPPKTERGNELLWQAIRELEPLHPSFVSVTYGAGGST
RGRTVEITERIATETTLTPMAHLTAVNHSVAELRNLVGRLAEAGVRNLLALRGDPPGDPM
GEWVRHPQGVDYAADLVRLIREAGDFSVGVAAFPYRHPRSPDVASDTEYFIDKCRAGADF
AITQMFFDADDYFRLRDRVAAAGCDVPILAGIMPVTRMSTVERSEQMSGAPFPPALAAEF
ERVADDPEAVRQLGVEQASRLCERLLAGGAPGIHFYTLNRSTATREVWHNLALPTVAAGG
>A0A2E4MFJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIKDKIKRPRRPVVVYEILPPREKDGTLNSYAANISSLLSQTHIDAINIPEVRDEVARG
ERPIKNQIRAEPREFGRLLQDIVGIEAIINRVVVHQELEKEMNWLEETNSKYEIENLITV
GGESRSIEYPGPSVNQALDAIRKNQKLDLLCGGISIPSREKESLRLIEKSENGSEFFTTQ
VLYDSSKIIKMISHYQKRCNELNTFPRRLLLSFAPVSSVKNINFLKWLGVDIPSETEKKL
KEDSQKMSEKSMQITINILNDTLKYLDDNKIVVPVGLNVEHIMSYNFQASIEMLQELSRI
YREYCIKTDIY
>A0A7X6NRA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MTLREKINSGKFIVCGEIGPPQSCDGDVIRRKAQYFKGIADAVNITDNQTAIPRLSSIAS
AKILLDEGVEPIIQMTCRDRNRLAIQSDLLGAAALGIRNVLCLTGDYQKLGDNPEAKGVF
DLDSIQLIATVAQMNSGYLLSGREMKKAPEFLIGGAANPFAVPFEMRLIRLYKKVKAGVN
FIQTQPVFDPELFIRWMEKVVEMGLHEKVAILAGVMPVKSVNTLLHMREDVPGVKINDVY
IRRMEKAADPQAEGIKIAVEIIQTVKNIKGIRGVHIMPFMWESIMPTVVKEAGLC
>A0A841E6L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomonospora salina|TrEMBL
MVGSSTRNGSAPVAASRSRDIRELLKTGEPTFSFEFFPPKTDEGLTKLWRVIRDIEALAP
SFISVTYGAGGGTRDLTVEITEQVATDTTLLPVAHFCAVDHSVSELRHLIGRFASVGVNN
ILALRGDPPGDPLGEWVKHPEGLEYAEDLVRLIKELGDFSVGVAAFPYKHPRSPDIESDT
KYLVQKCRAGADYAVTQMFFDPEDYLRLRDRVEAAGCDTPIIPEVMPVVKYSTIEMSEKL
SGAPFPRHLAEEFEKVKDDPESVRKLGIEQGQRMCERLLDEGAPGIHFITFNQSTATREI
YQQVAADRLPAMAAARP
>A0A418F0M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces astaci|TrEMBL
MGKIIDRLTELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPREQLREILKNVRAAGIRNILALRGDPPIGSE
RWKAIPGGFQNAVELIRFIREEHGDWFCIAAAGYAEVHTEAWNNPNLPPSDQVRRVDMLR
LKEKQDAGADFIITQFFFDVDKLLQWIRDCRQVGITIPILPGYLPIQTYNSFLKFTNWCK
TSVPPQVEDALVTIKNDDSAVKKYGIQLAVDTCRKLLANNLSLHFYTMNLATTVRTVLEG
LHLIERERGLPWGAPITRSKDGTLEKSIEQLPWCEQGLSGESTIIRENLRWINSMGFLTI
NSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPHLMQRLVVALADYPNLSYHAFSA
N
>A0A4Q4ZK68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides guangzhouensis|TrEMBL
MRNKNAALLIPLVEHARYEVLPTPSAEDAVLEHLPRERVVTVTASPGKGLGATLDLAERL
AGHGYVAVPHLAARMIHGRTELAEICDRLTSKGITRVFVPGGDAEQEDTYADALSLLEDL
TALGRPFQHVGITGYPESHPTINDDLTVQSMWDKRKYATHIVSNLTFDPGTIKAWVRRLR
ERGITMPLLLGIPGPVDRTKLMAMATRIGVGESTRFLVKHKGTLARLAAPGGFTGEKFLE
QCAPTVAMPGSLVEGLHVFTFNQIAQTEAWRADLLRRLQG
>A0A423XG36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytospora leucostoma|TrEMBL
MHIREMVAEAEKTGKPSFSFEYFPPKTLTGVQNLYERMERMYNFGPKFIDITWGAGGRIA
ELTCEMVNQAQAYLGLETCMHLTCTDMGLEKVNEALRKAYKAGCTNILALRGDPPRDKQK
WEAADDGFNYAKDLVAHIRKTYYGHFDIGVAGYPEGCDDNKDEELLLDHLKEKVDAGATF
IVTQMFYDVDNFLRWVGKVRARGIHIPILPGIMPIATYASFLRRANHMNCKVPQEWLDAL
EPHKNNDVAVREVGKILVANMCRKIIAAGIPHLHFYTMNLAQATRMVLEELDWMPTDQSP
LKQPLPWKQSLALGRRYEDVRPIFWRNRNKSYISRTMDWDEFPNGRWGDSRSPAFGELDA
YSIGLTGTNEQNRAKWGEPKSVKDVATMFVKYLNKELDQLPWSEAPLTSEADSIREDLID
MNARGLVTINSQPAVNGAKSNHPIHGWGPANGFVYQKAYLELLVSPDVFPELISRIEKNP
DLTFYAVTRSGNFRTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGMDW
ARCFDAGTPSRILLERMMNEWYLVNIGKSTFARKTLKYDSLTNGPVNNDFHQPRTIFEVA
SGLRVKDLDVEVQPDGPAAK
>A0A0N9VMC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1F8R2R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_57_9|TrEMBL
MPQFKTIYTQPKPVLSVEVFPPKTEHGTQNLYVELAHLAQHQPSFVSVTYGAGGSTRGKT
LELVQDIHARFGVLTVPHFTCVGSSRQDVRDYVDQAIAQGAVNIVALRGDPPHGEQEFRP
APDGFRYASELVAFLRSYNSQLDIAVAGYPEGHVECRDLTKDIQHLKRKVDAGASVVLTQ
LFYDNTDYFRFRDLAVQAGITVPIVPGIMPIIKFSQIQRITSLCGARIPTALSSALLAHT
DGSADQQAASIDYAIEQCRELMETGAPGLHIFTLNNGHATSSLVDALEGYFD
>A0A2A4MG62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIEHIDNAKDPLFSFEIIPPIRGKSAQEIIDIVKDLEPFNPPFIDVTSHPAEAYYEEN
TDGEVKRRVRKKRPGTISICGIIQNRFKIDTVAHLLCRGFTREETEDAIIELNYLGIHNI
LAVRGDETNYKKPVQAGRTVNVFASDLVKQLNDLRSGIYLDEIINADPVDLCIGVGGYPE
KHFEAPNLKKDIEYLKQKVDAGADYIVTQMFFNNADFFHFVDECRKAGITVPIIPGLKIL
NNPKQLTSXPKNFYVNIPTELSEEIEKNXKHTREIGVEWCVKQCEELLXSGLMXIHXYIM
SGAXAVTKVLKXLNK
>A0A2R7IQS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. HMWF023|TrEMBL
MSGAIGRLGPPPNWPADRAQRAQAFVSAVSLEVSAKAMPALCAEAARMAQGTTISIPYLA
SEGDDARLAAVRAVRELGFEPMPHLSARRIGSRAALERFMEHACSEAGVERCLVIAGDLS
TPAGPFADSASIIESGVLERAGIKVVAVGGHPQGHPVMSSVDRWRVLERKCQRIEARGMA
PLVITQFAFDADVVLTWLNELRARGITHPVLVGVPGPASIARLVRYAAMCGVSASTSMLS
RYGISIGRLLGKAGPDVFVDRLVDGLTEAHGQVSPHLFPFGGIAQSMDWVEHYRMRAGDE
CLAQMSVQLVQTPDLPLRCPCCGHRTLDERGTFRICAVCFWEDDGQDDYDADVVRDGPNG
CLSLTQGRANYKAFGASQMKDLPYVRLPFPHELP
>A0A1G0IDF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_45_12|TrEMBL
MTSRSISFEFFPPKSVEGMSQLASTASELATLRPHFFSMTYGAGGSTRNGTVEAVTLLQQ
RTPIPLAPHIACVGATREQMVELLQLYQTMGVQRVVALRGDLPSGMGQFGEFKYASELVA
FIREQTADQFDIEVAAYPEIHPQAQTTRDDLLNLKRKFEAGANSAITQYFFNPDAYFWYV
DECARLGIHMPIVPGIMPITQYSKLVRFSEMCGAEIPRWIRKRLEMYADDMPSIQAAGYD
IVHELCERLLKGGAPGLHFYTLNKHEPVMAVLENLGIVPSKQSNEYLLKSFSDN
>A0A4R8LZ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia rhizosphaerae|TrEMBL
MNPIELSFEFFPPKTQEGVEKLRATRAQLASLKPKFVSVTFGAGGSTQQGTLDTVIDMAK
DGVEAAPHLSCIGSSKDSLRAILNQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFRIEVAAYPEYHPQSRSPRQDLENFARKVKAGADSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDREAIRAFGLDV
VTQLCRRLVDAGVPGLHFYTLNGAAATRTICERLGL
>A0A3D5NXN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIEYLEKATETLISFEIIPPMRGRSAQEVYTILDQLIEFEPPFIDVTSHAADAYYVEQ
KDGSFKRYIKRKRPGTLGLCAGIKYRYKIEAVPHLLCRGFTREETEDMLIELNYLGIENL
LAVRGDDPNYQKAINPDRSKNNYAIDLVRQVADMNRGRFQDDILDSAQTDFCIGVGGYPE
KHEESPNLEADIRHLKEKIDAGAHYAVTQMFFDNQYFFDFEKKCRDAGITVPIIPGLKLL
TKPYQMKSLPSNFHVNIPDTLVAAMTAADSETEAQQIGVEYLKKQAGELINAGVSCLHFY
VMNDVHLVKEVVRSLK
>A0A851H108|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquitalea sp. LB_tupeE|TrEMBL
MNEQKKTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGHAAAPHLSCIGSTRENISAILNEYRNHGIRHIVALRGDMPSGMVAAGEFRYANELV
EFIRSEHGEHFHIEVAAYPEFHPQAKSAEDDLNNFVRKVKAGANSAMTQYFFNADAYFRF
VDEAQARGVDIPIVPGIMPIANFGQLCRFSDMCGAEVPRWLRQRMQSYYDDAASIRALGL
DVVTELCDRLLANGAPGLHFYTLNQAGLVSTVWQRLGL
>A0A7Y6D048|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. C9C3|TrEMBL
MSTHNFSIEFFPPKTAEGTEKLRATRARLAALAPKYFSVTFGAGGSTQQGTRDTVLEIIA
EGHDAAPHLSCIGSSRASLRAILEDYRAHGIKRLVALRGDLPSGYGAMDQASSEFRHANE
LVEFVRAETGDWFHIEVAAYPEMHPQARSPQDDVQNFVRKVKAGANSAITQYFYNADAYF
RFVDEAAKLGASVPVIAGIMPITNYTQLMRFSDMCGTEIPRWIRLKLASYGDDTESIRAF
GQDVVTQLCQRLLAGGAPGLHFYSLNQAGPTEAIWKTLVK
>A0A7Z1FWV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pseudomycoides|TrEMBL
MKLLDLLQRGIVIGDGAMGTLLYSHGLQSCFEELNVSEPERIISIHKQYVAAGADVIQTN
TYGANEGKLRMYGLEDRVKKINRAAVRHAKEAVTEKNAIVGTIGGMKHIGAVTTTDMERE
FMLLEQADALLEESVDGLLLETFYDEFELLHAVKVLRKQTNVPLIAQLALHEAGTTQNGN
SVDDVLKQLIEYGANVVGLNCQLGPLHMIESFKMIEIPKYGYLSAYPNAGLPKYVEGRYV
YEGSPAYFEEMAPAFIKQGVRLLGGCCGTTPAHIEAMKRALENEHPVTAKEVVKRAEVIT
TQRVNVMDRITLAEKAKKETTVIVELDPPKTLDTQRFFEGAKALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPILTHLTCRDHNVIGLQSHLLGLAALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNNGRSILGKTIGATTHFSIGGAFNPHVRHIEAAVKRM
EKKIAAGAEYFLTQPIYDAAVIRNVYEATKHIEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRRRMDGHKTSEEAVAEGIHISKELIDVAMELFNGIYLITPFLKYEVTEALVRYIQ
AKKEQKEGMNV
>A0A7G6ULP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas mexicana|TrEMBL
MPIPVSFEFYPPKTDEQRAQLDRTAYKLKAHAPEYVSCTFGAGGSTLSYTSETVRHLNQH
HGFDAAPHLSCVGGSREEIRELLRLYRALGCKRIVALRGDLPSGMGHPGDLRYASELIEF
IRAEHGDTFHIEVGAYPETHPQAEDALTDLRHFKAKVDAGADGAITQYFYNPDAYFHFVD
AVRRLGVDIPIIPGIMPISNFTQLRRFSEACGAEIPRWIGKRMQALGDDADAVRDFGADV
VAGLCERLIAGGAPSLHFYTLNLAKPTQTVLSRLGWAA
>A0A7K2LC99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4920|TrEMBL
MALGTPSTRTDHARTVREMLATGATSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVKATQDIAAESTLTPVAHLTAVDHSVAELRNMVGQFADAGIRNILALR
GDPPGDPMGPWVEHPQGVTYAADLVRLIKEAGDFCVGVAAFPERHPRSEDWDTDVRHFVD
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCDTPIIPEVMPVTNVRQLERLSQLSDAKL
PDDLKERILAAKDDPAAVRSIGIDFATRFSAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A7Z1G5F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pseudomycoides|TrEMBL
MKLLDLLSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKAAVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEKVDGLLLETFYDEFELFHAVKVLRKQTDIPIIAQLALHEAGTTQNGN
DVNEILTGLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYL
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPAHIKGMKRAITNETPVTEKQIFQRPQVIH
THAKRSRTHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARLLKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLIHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRTILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIKEVYEATKHLEHPIFIGIMPLVSKRNADFLHFEVPGIT
LPDEVRQRMDGHETQEAAIEEGIRISQELIDATMKYFNGIYLITPFLKYEITENLVKYVR
EKQEVKEVINE
>A0A2K8PT01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lavendulae subsp. lavendulae|TrEMBL
MTALREALAGGVPSFSFEFFPPRTDAGSRVLWEAIRRIEALAPTFVSVTYGAGGSSRDRT
VEVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADVGVRDVLALRGDPPGDPNAPWV
RHPQGLTHAHELVSLVRDSGAFSVGVAAFPERHPRSPDWESEMRHFVAKCRAGADYAITQ
MFFHVDDYLRLRDRVAAAGCDTPIVPEIMPATDVRQIGRFAELSGASFPGELARRLDAVR
DDPAAGHAIGVEYATAMAQRLLAEGAPGLHYITLNRSTATLEIHRNVLNSRSTQHVLAAH
R
>H8FEG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. mangiferaeindicae LMG 941|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGCAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSGDDADAVRAFGAEVVA
ALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A5M8E843|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas veronii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYQQAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2M7KBQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium CG_4_8_14_3_um_filter_31_14|TrEMBL
MKVAEILQNTKKTLISFEILPPLKGDSIEGIYKTIEPLLEFKPPFLNVTYHREEVVYKKH
SNGLLERRIVRKRPGTVAISAALHYKYGIEVVPHIICGGFSREETENALLELHFLGIRNV
LIIRGDPDKSLREFVPEEGGNAHAIDLVKQVMNLNKGIYLDDELLNSTKTCFSVGVAGYP
EKHPEAPNMKSDLAYLKNKIDAGAEYIVTQMFFDNKKFFDFVAQCRKIGITVPIVPGIKS
VSVLSHINILPKTFYIEIPEALEREAKKCKTNDEIKQVGIEWAVAQSKELIAAGVPVIHY
YTMGKSDNTRKIVEAVF
>A0A1H8QWE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter gossypiicola|TrEMBL
MKIPEHIANANGKTLFSFELIPPLKGQSIQGIYNAIDPLMEFKPPFIDVTTLREDFIYKQ
HPTGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENALIELEFLGIEN
VLVLRGDARLGDSSFVPTPNGHCYATELLQQVVNLNNGIYLHEDHGNTVKTNFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVEMGAQFIVTQMFFDIDKYKEFVNGCRANGINVPIIPGLK
PITTSKQLVTLSKTFHIDIPEDLSDAIHACATEKDVKEVGIEWMINQCKELIAFGAPVLH
FYTMSNAGPTKRIAEAIF
>A0A850CV74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbellaceae bacterium|TrEMBL
MANGLPSTLPGGAPTIRELLAAGERSFSFEFFPPKTPEAEEVLWRSIREIEQLHPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWIAHPEGLNHAIELVELIRSLGDFCVGVAAFPDKHPEAASLEADAQVLAA
KAQAGADYAITQMFFGADDYFRLVERAAALGCEIPVLPGIMPVTNIKQIQRMAELTGMAL
PAEVTDRLLAVEDEPAAVREVGIEIATELCERLLTGGAPGIHFITLNRSTATRQVFRNLQ
SANVS
>A0A0R3AS54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas paralactis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHVEVAAYPEMHPQARNFEDDLHNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1E5QQF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desertifilum sp. IPPAS B-1220|TrEMBL
MSKLRSAIQAGEFLITAEVAPPKGGDPAHMLEMAKLLKNRVHAVNVTDGSRAVLRMCSLA
ASALLQQQGIEAVCQVACRDRNCIGLQGDLMGAYALGIRNILALTGDPIKAGDHPQSKGV
FELESVRLLQLIDKLNHGIDFNDKPLVDGTVELFAGAAVDPQCGSWSGLQRRFERKLEAG
AQFFQSQLITDFERLDKFMTQIAATSGKPILAGIFLLKSAKNAQFINRCVPGVQIPDSII
ERLAKAEDPLQEGVKIAAEQVQLARQLCHGVHMMAVKREDLIPQILDLAGISPL
>U5T594|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spiribacter curvatus|TrEMBL
MKTVLEAVPPELHRGQAAVEAVVEKVARVQAARPLDSVNIPEIHEEPSRSDQGERRQPFA
PRLAPRDLARILHDRLGVECMINHVVVHHPSEQALIDWANETWEVYGIRRFVLVGGGRHS
VRYPGPSVTRANRLLRERTAIDALRIGNICIPSRAGEADRIAGKVSAGADFFTSQILYEP
DAFIGMLDALAQRDRLPREILLAFCPIRNARNLRFLLWLGVSVSDALYDWLIEDDAVVLD
RSLAQIRRAWARIITHQRAQGRDWPALDVNLAPIGPIPPTVTVGLADELATLHDAPANGL
>A0A257DBP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium PBB1|TrEMBL
MSNQLPLSLEFFPPKTPEGVVKLAAVRQELYALKPDFCSVTYGAGGGTQDGTLATVRAIQ
AEQVEAAPHYSCIGASAAGVREQLAQFKAAGLRRIVALRGDLPSGYGRSGEFRYASDLVS
FIRQETGDHFHIEVAAYPEMHPQAASPRADLQAYVTKVKAGANSAITQMFFNTDAYFRFV
DEAYALGADIPVVPGIMPITNASGIMRFADGCGTEIPRWMRLRLTGFGDDTESIRAFGLD
VITDLCDQLRTAGVPGLHFYTMNQSAAVLEICKRLGL
>A0A212UE33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter gelipurpurascens|TrEMBL
MKVTEHLTRADGKTLFSFEVLPPKKGENIQNLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGFLEKKTVRKRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFKPDPDGHSYAADLIGQVADLNKGAYLDEEQDDTWATNFCIGTAGY
PEKHFESPNYAADLRYLKHKVDRGADYIVTQMFFDNEQFFKFEKSCREAGITVPIIPGLK
PLTTKSQLSMLPRSFYLNLPEELADAVHLAPDNNAAREIGIEWCINQSKELMAHGVPCLH
YYSMGKSESIRRVAAALF
>A0A2N3BBH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HGW-Alphaproteobacteria-4|TrEMBL
MPAPRVSFEFFPPQTLDASFRLWETAQVLAPLKPSFVSVTYGAGGTTRKLTHEAVTTIGR
NYGLNVAAHLTCVDATRAETLEIVEAYAQAGVREIVALRGDAPKGAERFAPHPEGFASSV
ELIEALAADGRFTIRCGAYPEPHPDATDPQADVRWLKQKCDAGATSAITQFFFEAETFFR
FRDAAEKAGVKAKIIPGILPIQSWAGAKRFAQRCGTSVPASIEEAFAAAARDGREELLAT
ALCTELCDDLLQGGVEDLHFYTLNRPGLTRDVCHALGVTQSPNLEQVA
>E6V797|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax paradoxus (strain EPS)|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPQFCSVTYGAGGSTHQGTFGAVQEILNE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFHYASDLVAFI
REETGSDFHIEVACYPEVHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDE
VRKLGIDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLCDGGAPAIHFYTMNQSTATLALLERLD
>A0A2J8BBT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera genomosp. type_2|TrEMBL
MSVKNKTTFSLEVFPPKKEMPLASVYPTLTELSVLHPDFISVTCGAQGTGSNRTAEIAAT
IKEQFNLEPVAHLPGIYLTKDEVCNTLKELKKHRIHKILALRGDMTPEKEPAHDFAHASD
LIRFIKKESPDFHIIGACYPEGHVESKRPALDIIHLKEKVDAGASSLISQLFFDNTLFYR
FLERCEIASIHVPIAAGIMPVTNKKQIERMVSLCGATLPLHYQHLIAKYGDNPVAMRDAG
IAYAISQIIDLLAHGVDGIHVYTMNNAYIAQKIADAIRTLL
>A0A0U1LWE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces islandicus|TrEMBL
MEKITDKIAALPPDGHYFSLEFFPPKTQMGSVNLQARLERMAQALRPLFVTVTWGAGGTT
ATKSLELAEICQRQLQLTTCLHLTCTNMNRKLIDEALEEAKALGIRNILALRGDPPRSGE
YNMEGDDDSNKDFTWAIDLVRYIRRAHGDYFCIGVAAYPEGHPGESQTDVQDPEKDLPYL
VEKVQAGADFIMTQLTYDIEAYTKFENRLRTHPSGAMKTMPIIPGLMPIQGYKILTRVTK
LSGAHIPPPILSRIEAVKSDDEQVKQVGVDIVSEIVNDIKGLPCPGPRGYHFYTLNLEKA
VSFVLERCDLIPPYSEPDDVAVEEVPIEITQMNGADSAKPAFARRRASSINSGPHNRVIV
DKLHVPVDQQSEHSSRKSVTYETLASSAGVPALNPPPRSTQLQISEGIGSLGREATWDDF
PNGRWGDARSPAFGEIDGYGPSLHVNANVAKQLWGFPVSNSDISDLFRKHVSAQLYIVPW
SEGGAAEESNLNAETETIKPQLLKIIEKNWWTLASQPAVNGVRSDDPVFGWGPPGEGFVF
QKAFVEFFCPSSDYKTKVKPALLKHGDEEFAWFATNCAGYFESSFSIPNNTTPDGAPADA
PTDADEDYVEVSDSTGMAVTWGAFRGKEITTPTIIEDVSFRAWGEEAFRIWDEWRRIYPR
GSATERFLGETKNDVWLVCVIGHRFGAGTEPGSEEEKAETNMLWDVLVNA
>A0A1V2QYF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium actinidiae|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWESGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A6M6C3I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus warneri|TrEMBL
MSQFLNKLQNNVLVADGAIGTIFYSEGLDTCPEAYNLTHPEKVEDIHRSYIDAGADVIQT
NTYGANFEKLKAFGLEHKVKEIHKAAVQIAKKAANEDTFILGTVGGFRGVKQDDLSLSTI
QYHTEHQIDTLVDEGVDALLFETYYDLEELKGIVISTKRKHHIPIIAQLTASNTNYLVDG
TPINDALKQLVECGVDIVGLNCHHGPHHMQRSFSHIELPDKAFLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIRYIKTSVENLRPVTHKNVIPINKKV
NRKKDINFKQSLTSKVKQGPTVIVELDTPKHLDTDQFFNNIGKLDDADIDAVTLADNSLA
TVRVSNIAAASIIKQRFNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEATKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEEVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITTHKEAIL
>C7HAY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii (strain DSM 17677 / JCM 31915 / A2-165)|TrEMBL
MKDIRELLQTRPLLFDGAMGTYYKAAPGVECEQANLTDPAGVLAVHREYLAAGADAVKTN
TFSLPRLAAAHTPGWEQLAQAGWQLAVQAAGETGAAVFADLGPAPDTEAVPAGQVYTAVA
KQFAALGARNFLFETLSSDAGLLDAVGAIRAEVPDAFVLVSFAVLPDGYTREGMYCKDLA
RRMQESGIVDAVGLNCVSAPGAMRTLAKQLGGTLPLSVMPNAGYPVVTRTQVKYQGRPEY
FARELGRLAAEGTVQILGGCCGTTPAHIAALRAELDSLTVVKKTAPAEEFSTVKEQTVEN
EDAFLRKLNAGEKVIAIELDSPRNADLTGYLEGAKKLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGLCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPGPMTVFGALNLNARNFDVELRRAKEKLENGMSGFL
TQPVLSAQAVENLKKSRETLGADARILAGIMPVVSQRNAIFMENEINGIHVEDWIIEKFA
GLDRAQGEELGLAISLEMAKAALPYADGLYLMTPFNRVALMERLIGRLKQEVLGAY
>A0A1I2GKC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. DSM 46838|TrEMBL
MSELLAAERPTWSFEFFPPKSPDADPQLWQALRELERLRPSFVSVTYGAGGSTREGTVAI
TERIAAETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGLDPQAEWRAH
PQGLNYAAELVELIKSMGDFSVGVAAFPEQHPRSPDFETDVSRFVDKCRSGADFAITQMF
FRAEDYLRLRDRVARHGCEVPIVAGVMPVTSARQIARIVQLSGQAFPSDLADRFAALDGD
RPEDKAAVRALGVEVATELCRTLLAEGVPGIHFITMNRSTATREVYANLVAGSPRQPEPV
SG
>A0A1H3LNV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentibacter algarum|TrEMBL
MKGPLMTPDVSFEFFPPKNLEAAFKLHEAVQSLAPLAPRFVSVTYGAGGTTRALTREAAE
TLHKTAGLRVAAHLTCVDATREETLEIARGYAKAGITDIVALRGDAPKGAGGFRAHPEGF
ADSVELIAALKAEGNFNIRVGAYPEPHPDAAYAGADIDHLKRKFEAGADEAITQFFFDPI
HFLRFRDACAKAGIDGMITPGIMPIENWNGAKRFAQSCGASVPSELDDAFSKAARDGREE
LLATAQATELCDILMQEGVSRFHFYTLNRPSLTRDICVALGLEPRAALRNVA
>A0A1G9CSH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meinhardsimonia xiamenensis|TrEMBL
MKTPRISFEFFPPQSLDASFRLWETVRTLAPLRPDFVSVTYGAGGTTRDLTHEAVETIHR
HYGLNVAAHLTCVNASRAETLEIAERYARAGVTEIVALRGDPPRGQGRFTPHPEGFASSI
ELVEALARTGKFTIRVGAYPEGHPESADMKQNVEWLKRKLDAGASSAITQFFFEAESFFR
FRDAAAAAGIDAPIIPGILPIDNWEGVKRFAARCGARVPAWLDEMFATATRDGRQHLLAT
AVCTELCTDLIEGGVEALHFYTLNKPALTRDVCHALGVTPEVVLENVA
>A0A551YKT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa Ma_QC_C_20070703_M131|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNVSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>D4YHV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1)|TrEMBL
MTDFQRGNGTSLSFEVFPANTQVGTKKLIQTLNELQDLQPNFISVTCSNNKANIEETTVK
IADYVTNTLRIPTIAHLPAAYLSKQQVSTILGQLEKLGIRHVLALRGDIVEGIPPKRDFS
YASDLVTFIQEQAPYFDISGACYPEIHPDSDNRISDIKHLRKKVEAGCSQLITQLFFDNE
QFYQFKEGCSLAGIDAPILAGIMPIVNRKQALRLIKVSSSQLPKKFLAILEKYEHNPVAL
RDAGLAYAIDQIVDLVTQGVDGIHLYTMNQSDTARQIHQATKSLFQTTELLGV
>A0A4R8RYZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides salmoniphilum|TrEMBL
MTTHPLDRDASVAELRDPGSIADRLAAVQPGDVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDLE
RDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELASSTLPAALEEQLLQAAGDGSEENRDEVRKVGVEVTTAMASRLIAEGVPCVHFM
TLNFARATSEVLENLGLRVTPGTGRA
>A0A239AMT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. RU38E|TrEMBL
MSLPVADLSAPLITAPGDLTVSFEFFPPKTEKMHENLWAAIHRLAPLKPAFMSVTYGAGG
STRERTHATVTAIQDQTGIPAAAHLTCVAATKEEIDEIARAYWDAGIRHIVALRGDPPPR
ADGTGGLGGRGYEPHPGGYAYAADLVAGLKRIGDFDISVACFPEVHPEAPSAQVDLDNLK
RKVDAGANRAISQFFFDADAFLRFRDKTAAAGIDVPMVPGILPILNFKKAVEMGEKCNTA
IPAWMRELFEGLDEAPETRHLVAATVAIEQCRYLARHGVKQFHFYTMNRADLTVAICHML
GVRARG
>A0A1I5CC93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sp. YR627|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIDSIYDHLDPLMEFKPAFVNVTYHRSEHMFKKR
ADGSFEKVEIRKRPGTVAICAALMGHYNVDAVPHLICGGFSREETENALIDLNYLGVDNV
LVLRGDAPKNETFFEPEPNGHRYADQLLQQVVHMNNGIYLEEDLQSGVKTKFCIGVAGYP
EKHFEAPNMQTDMSYLKKKVENGADYIVTQMFFDNQKFIEFVGKCREAGITVPIIPGLKP
ITTRKQLTILPRTFHVDIPTELSTEILKCKTDKEVEEVGTEWLIKQSRELKQFGVPVLHY
YTLGKPHVIHKAVAQVV
>A0A806HAW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri DSM 10701|TrEMBL
MTSANRPSISFEFFPTKTEAGHEKLLATARRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKQELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKARAGASSAITQYFFNADCY
FYFVERVRKLGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMNSIQA
FGTQVISEMCEKLLAGGAPGLHFYTLNQAEPSLAIWDNLGLSR
>A0A6L5D8K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ephemera danica|TrEMBL
MEATYIKMAKQALFESYVHNDSLPLCLRSGNCKSCINASDNNPPLYEMVQSRVNSGDIFF
SVEISPPKTVTGTVHSLSNLHEMKHGGALYCSVTWHPGNDPGGTSLTSSMTIAGFAAKHS
GCETMLHMAGSHISHQQMDEYLHDDSECEKSDFPYAVDFVQHIEQKFGKQFTIAVAGYPC
GHPEAQSYLQDLQYLKSKVEAGANLILTQMFFEAETFIKFVHDCRSLGISVPIIPGIMPI
QSYASLMHMVRLTRVQLPTNFSRDLEQIKHHDEAVESYGIHKSVELCQKIFEAGVAPGIH
IFTLNRSSAPIELCKRLGMWLHGPMLPLACCIKDVNDQDKGLSYKN
>A0A7Y7H6H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. SG538B|TrEMBL
MKIPEHIANANGKTLFSFELIPPLKGQSIQGIYNAIDPLMEFKPPFIDVTTLREDFIYKQ
HPSGLLEKLSYRKRPGTIAICAAIMNRYKVDTVPHLLCGGFTKDETENALIELEFLGIEN
VLVLRGDARLGDSSFVPTPNGHCYATDLLQQVVNLNNGIYLHEDHGNTAKTNFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVEMGAQFIVTQMFFDIGKYKEFVNGCRANGINVPIIPGLK
PITSSKQLVTLSKTFHIDIPEDLSDAIHACATEKDVKEVGIEWMINQCKELIAFGAPVLH
FYTMSNAGPTKRIAEAIF
>A0A6J4TCK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Sphingomonadaceae bacterium|TrEMBL
ATVARIARETSIEAAAHLTCVGASRDEIAEVARDYWDAGVRHIVALRGDPPVEGEKFVAH
PDGYASAAELVAGLRAVAPFDISVAAYPETHPDALSERHDLDNLKRKLDAGASRAITQFF
FAPETFLRFRDAAAAAGIDAEIVPGILPVANVAQARRFAAMNGASIPGWMDRLFEGLDDH
PTARQLVAATVAAELCGRLYEEGVRHFHFYTLNRAELAYAICHLLGVRPKAREQAPVLIQ
SAGVAA
>A0A6J4SUD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Sphingomonadaceae bacterium|TrEMBL
MSGIEARRSGASPLFADKHGDIEVSFEFFPPRSDKMMESLWAAVETLSPLAPRFLSVTYG
AGGSTRERT
>A0A1Q6SRX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:10041_57|TrEMBL
MNIQEYIRTHKLITDGAFGTYYADRFQTQDMPELANISFPQRVTAIHQEYIEAGARLLRT
NTFASNTILLHADMNEVRANITAAVNLAKEAVKGREDVFIAGDIGPIPSDEVISREELEE
QYYQIARVMLDQGLKILTFETFHELQYILPAIGRIKEEAPDTFIMVEFTVNQFGYSSAGL
SVKSLLKDASACKDIDAVGMNCGIGPAHMEKLLDQAGVGISGTKYRIALPNAGYPRRTSS
RIRYSNSSAYFAAKVEEMAAQCELDIVGGCCGTTPEFIRQLSQGLDTTPCPPRTAAETSK
TEQVVPQRKGFLYDEQGNLKKKKLIAVELAPPMGADDEKVLEAARLLQKSDVDVLTFPDS
PSGRTRIDSVLMAEKVRRETGMEVMPHICCRDKNAIAMRSLFLGAYINDITNMLIITGDP
VPSLVRQTIKAVFNFDSVGLMKIAQEMNTENFPARPLSYGGAISQGRKNLDVEIMRVKKK
MEAGAEFFLTQPVFSKEDAERVRRIKQETGTRILCGIMPFVNKRNALFMKNEIAGIIVPD
EVIARYPENGTKQEGEAVGVEIAREIMEFTADFADGYYFSFPFNRVYLLEQILR
>A0A7Y5W5V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pirellulales bacterium|TrEMBL
MFDGPMGTEIYRHHVFTNRSFDELCLSDPKLIRQIHADYCNAGADVLTTNTFGANRVALG
RFGLAEKLREICTAGAKIAREVADSAGRPVWVAGSVGPLPGQPQYEDQIVEMVVEQVQAL
LAGGADFILFETQPTRQSLERCAAAMLRLPDVPFVLSFTIVQRAETASGEPVERMLAPLP
EDVPQPIAWGMNCGAGPDGLLSAVEKAVHLTTLPLIVQPNAGMPREVENRNIYFCSPEYL
TSYARQYISLGVNAVGGCCGITPDHIREMAEAIKPLARSHVARVMVATPAESAELKESTP
IGGRSRLAWRLTNGKWCTSVELLPPRGWDLRSTIEKSRTLYRHGVDAINIPDGPRASSRI
SPLIVAERIQQAVGIEVVLHFCCRDRNLIGMQADLLACAACEIHNILFITGDPPKLGNYP
HATGVFDTDSIGMVAVQKRLNSGLDLGGQAIEPQTSAFIGVGLDPTALDHKRELDRFRQK
VEAGAEFAITQPVFDPEALLRFLDEVQPFGIPILAGIWPLASYRNAMFLHNEVPGVEIPD
AIMQRMASVSSREEQMAMGVRIAQEAVRRVHDRIAGIQVSAPFGNVETALAVIEGWEE
>A8RYH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster bolteae (strain ATCC BAA-613 / DSM 15670 / CCUG 46953 / JCM 12243 / WAL 16351)|TrEMBL
MKTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTRDDVLLILEQLKEQKIENILALRGDRTADREPAGDF
RYAADLVEFIKNHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFRERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFISMMERYGDNPIAM
RDAGIAYAVDQIVDLAAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>A6D0D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio shilonii AK1|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSTPTMEETLWKSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSETGLVAAPHLTCIDASRDELIDIAEDYWSNGIKNIVALRGD
IPAGGGQPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAGMNKVKVPGWMQKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQV
>A0A1S1PXL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. RSm-3|TrEMBL
MMIAPQSESREKAPLADLLSHYSIEVTSRDLPSLQSMTATLPPGSEVFVAHLPKEDIGLL
VRAAAGLRDAGFVPVPHIVARNIRNRLELDTMLARLSEEAGVRHALVLGGDRDDAAGTFG
SALDLIETGLFQTYGIGRIAIACYPEGHPRIAGAVLDTALTAKVDAAARAGLDVLLVSQF
LFDQKPLLSFARRLRERGVTVPLRVGIAGPASRTKLLKYALRCGVGASLRALRERSEVAR
NVLSGETPEELLIDIAAAEAAEPDLGISGVHFFTFGDPAQSIRWAEQQAASD
>A0A4V5UYH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbidospora galbida|TrEMBL
MALGLPSRFPDRVATVRELLAAGERSFSFEFMPPKTPEAERQLWRVIRELESLKPTFVSV
TYGAGGSTRDRTVDIVERIAHSTTLTPVAHFTAVNHSVRELRHLIGRFADAGVRNILAVR
GDPPGDPMGEWIAHPEGVHYAEDLVRLIRQSGEFCVGVAAFPYKHPRSPSVESDVDYFVR
KCRAGADYAITQMFFEADDYLRLRDRVAASGCETPIIPGIMPVIKFATIARSEQLSGAPF
PAKVAERFERVKDDPDAVYQLGIEHGVELCRRLLDEGAPGIHFITFNRSNATREVYQALM
PAVPAV
>A0A077WF73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lichtheimia ramosa|TrEMBL
MKVIDKIHRAEQEGRFFYSFEFFPPKTPQGVQNLYDRIERMQRFGPEFIDVTWGAGGSSA
DLTTEMVANAQAVYGLETMMHLTCTNMPVEKIDQALKAAKDCGCQNILALRGDPPKGQLN
WESCDNGFEHAVDLVRYIRKQYGDYFCIGVAGYPEGHIDNPDKEDDLRRLKEKVDAGADL
IITQLFFDTNAFTTFVARCRDIGITCPILPGIFPIQNYNGLKRVISFSNNQVPQKIWDDL
EPIKDDDAAVKEYGINLTVDFIREFRKAGINGFHIYTFNLERSTRLILEKLDLMPAMEDV
KPLPWNPPLTAKRAKENVRPIFWKNRTKSYIQRTESWDEFPNGRWGDSRSPAFGELDGYG
VSLKYPQQECLKMWGHPATTDDIALLFAKYCKGSIAGIPWSAQQLEAETQIIRQRLAAIN
LLGFLTINSQPAVNGAKSSHPVYGWGPKNGYVYQKAYLEFFVSPEQLDQLTAKISKNPQV
TYYAVNKKGDLRSNTMQEGDQPNAVTWGVFPGAEVIQPTIVESMSFMAWKDEAFELWNEW
ARIYDRESDSAKLMLDIMNNWYLINIVHNDFQDENGIWRLFDLEVDQIANQKQHLFDLIA
>A0A2A9KDE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas sp. PA-H2|TrEMBL
MAKKNFSIEFFPPKTPEGTEKLRVTRAKLAELHPRYFSVTFGAGGSTQKGTLDTVLDIRS
EGHEAAPHLSCLGSSRESLRAILAQYKDHGIKRLVALRGDLPSGYGAMDFSSGEFRYANE
LVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDVQRYVSKVKAGANGAITQYFYNADAYF
RFVDEAQKLGATVPVVAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTDSIRAF
GLDVVTQLCERLLAGGAPGLHFYTLNHSPATIAIWQRLKL
>A0A0K2H0S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium lactis RW2-5|TrEMBL
MTMSSTMPPTPGRQVTIRQALSMPSAGSIPFSVEFMPPRDDAAEQRLLRAAEAFHDLGAS
FASVTYGAGGSSRNRTLRIAQRVSRQPLTTLVHLTLVEHTVDELREILRSYLDRGLTNLL
VLRGDPPGEPLGPWVQTEGGLRYASELIELIRSEPEFAKFEIGIASFPEGHYRSPDLEHD
TKYTLTKLRAGAEYSITQMFFDVEHYLKLRDRLAAADSEHGQKPIIPGLMPITSLRSVRK
QVELSGAKLPAGLEERLIAAAAGDEQANKDEIRKVGIEISTQMAERLISEGVPGLHFMTM
NFARASQEVLHNLGMAPAWGTGQDMLRGGF
>W2EXA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbispora sp. ATCC PTA-5024|TrEMBL
MALGLPSRRPDRVPTVRELLAAGERSFSFEFLPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVQIVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPRGGDPLDDWIKHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTEFFV
QKCRAGADYAITQMFFRADDYLRLRDRVAAKGCDTPIIPGLMPVTQMSTIARSEQLSGAP
FPPEVAARFEAVADDPVAVRRLGIEHAVDMCRTLLEEGAPGIHFITFNRSSATREVFQAL
QQTPAPAGS
>A0A3P7MSL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cylicostephanus goldi|TrEMBL
GYPLGHPEAPSYKADLLYLKSKVDAGAQFIITQLFFEAEVGSEFRMHQDQGSYWVFEQFV
RDCREMGITVPIIPGIMPIMIMNSFVTKGYDSIRRIAKLSQLTIPEKVLMDLEPIKHDDD
AVMKYGTVKVCLVCFRRPWPYFAQKRPKALNSAKFDNASAEGAFRRF
>A0A6P6D545|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Octodon degus|TrEMBL
MAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAMNYCGLETVLHMTCCQHSPEEITGHL
YKAKQLGIRNILALRGDPVGGQWESEERGFDYATDLVKHIRSEFGDYFDICVAGYPKGHP
EAGSFEEDLKHLKEKVSAGADFIITQLFFEADTFFRFVKACSEMGITCPILPGIFPIQSY
SSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAICNYGIELAVSLCQELLASSLVPGLHFYT
LNRKMATTTVLKRLGMWTEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQDWN
EFPNGRWGNSSSPAFGELKNYYLFYLKSKCPQQELLKMWGEELSSEESVFEVFAHYLSGE
PNQHGHKVTCLPWNDEPLAAETSLMKEQLLRVNRLGILTINSQPNVNGKPSSDPIVGWGP
SGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWG
IFPGREIIQPTVVDPVSFMFWKVKGGRSLPHPLENLEETALPSPKVLTKGHNLRASRVSL
QGHTCSLVFLRSVGMAQALGLALLLYLSTKAAAEAPGVRSWLGGILLTLRVCVCVRTRAR
TCAHTCVG
>A0A7X7IN05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MALFTPLRRWQPAFRPFSRQPAAKRLLALAERVVKGPLFGCRMCGNCLLQETAFICHMAC
PKGLRNGPCGGVNNGYCYVDPARRCAWYLIYERSRRMHREHKLLEVLPPVDWDRAGTETW
GEVVRVARKVGLRKIFIPSAREGKKLGEVLEEKVFRPIRQPDWWKGDSEYHPPAVNEPQS
ALEKELRSGSFVITAEVTPPLSPATVRLKEKIMLVKPCVAAVNFTDGSSAVPRMSSAACS
AVAASLGVDPVLQISARDNNRNSLQSLAIGANAIGVHNILCLSGDSPRIGPTPRCNMNIN
DLDSVQMLWILRRMRDEGIYLDGRQIKNRPRIFLGAAAAPYAMDPAMQAIRIRKKINAGA
QFLQTNLVFDPDSLDPLLEQLDKEGLLDKVFILAGVCPLKSLRLARYLNDNIPGVNVPEQ
VMKRLTDAGDRFTEESIAITVENVKKLREKKGVNGVHMMPLGWEEAIARVIDRAGLTPGS
IAQ
>A0A7X8A6D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVTEVLSRSKETRFSFELLPPLKGSSIQVIYDAIDPLMEFNPLNINITYHQSEVEYRRL
PGGLLEKRIIRKRPGTIGIAAAIMNKYQVMVVPHLICGGFTREETEDALIDLHFLGIRNI
LALRGDPQKGEKYFIPEEGGHAHTVTLVEQIINMNRGIYLDENLKNAIPTDFCVGVAGYP
EKHFEAPNMETDLRHLKAKIDAGAEYVVTQMFFDNRKYFDFVEQCRKAGIHVPIIPGIKP
VNTLRDIELLPRAFHIDLPEELVHEVQKCKTNQEAKEVGIEFCIAQSKELVRAGVPAIHY
YTIGISDNIRKIASAVF
>A0A2T0GYY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora mortivallis|TrEMBL
MSTNERQQLRHYLHHARYEVLPLRGALEQAQDLPEGTTVTVTSSPAKGIEATLDLAARLR
GVGMHVVPHLAARLVRDNAHLKELLDRIHGLGFTEVFVIAGDADQPAGGFTDALSLLRGM
EEIGARPYRVGITGYPEPHSFIPDRMTIQATDEKARYADYIVSQICYDPNTIASWITAMR
ERGVRLPVYVGAPGSIDPTKLLRISMKIGLGQSMRFLRKQHGVVGKLLSRYTPETMFEEL
SPYIVDPEYNIAGWHLFTFNEITRTRQWAVETADRLQEVPA
>A0A6C0P774|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus rhizovicinus|TrEMBL
MKPDLREALQTRILTGDGAMGTYLYGMGFPVGVSYEEFNLLRPEVIADVHRRYYEAGARI
IETNTFSANLASLTNYGLDNEVEAINRAGVRIARSAVGSDAYVVGAVGSIRAGKRKNMSS
SLLEQLFRQQIGALLSEGVDGILLETFYDLEEAMLALRIVRSLSDTPVICQFAVEKEAVT
LDGKTIEAVFESLRLEGADVVGFNCRSGPNGILRAIDTINGDVQLSLSVFPNAGIPDYVD
GKYHYSSTPEYFAESARKFADRGARIIGGCCGTTPEHIAAIAAALDGYVPQPVDPADLLQ
TAAKERVVISDNGAPGRASNLEPTIVDLVQERHTVIVELDPPRDLDIHKFMEGAKALKAI
KADAVTLADNSLAVTRMSNIALASLVQQQVGIRPLVHIACRDRNLIGTQSHMMGLDALGI
DHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGVAFSGKPLKQKANFITGAAF
NPNVKYLDKAIARLEKKIDTGADYIMTQPVYDRELIIRIAEATKHLQVPIFIGIMPLASG
RNAEYLHNEVPGIQLSDEVRKRMAGLEGEAGRAEGVRIAEELLDTAMDHFKGIYLITPFM
FYDMTVKLTDYVWRKTGSLTK
>A0A7J6NYW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perkinsus olseni|TrEMBL
MARLIDKIQDRWDHDRDNGESTRVPFFSFEYFPPKTDMGVQNLYERLDRMAELGPMWIDV
TWGAGGSTSGKTFEICRNALTYHGLDVMMHLTCTDQPVKEIDEVGIRNILALRGDAPMHS
SEWKACQGGFSHAVDLVRHIRGKYGDYFCIAVAGYPEGHLEAESMEEDLAHLKEKVDAGA
DLIITQLFTTRKCFSTLLPQYEHWVSKYQFSLA
>A0A840E4S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lewinella aquimaris|TrEMBL
MRVTDHFEQAKGQTLLSFEVLPPLKGGSMQAIFDTLDPLMEFKPPFIDVTYHREEYVYKK
RPSGYYEKTAIRKRPGTVGICAAIMHRYGVDAVPHLLCGGFTKQDTENALIDLAFLDVQN
VLALRGDARKFEGRFVPEKEGHHYASDLVKQIVDMNQGHYLDELIKDEHASKTNFCIGVA
GYPEKHFEAANLEHDLRYVKAKVDAGADYIVTQMFFDNQKYFDYVDACRKVGINVPIVPG
LKPVTKLYQLNALPRLFHVDLPDELVCSITKAKNAEGRIQAGIEWCVAQSKELKERGAPC
LHYYTMGDSSTIRAIAEAVV
>A0A359CYN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKIVDLLNASEKTRFSFELLPPLKGNDINTIYMTIDPLLEFNPAYINITYHQEEIIYKKH
SSGLLEKKTVRKRPGTVAISAAIKYRFKDVLVVPHIICGGFTKEETENALIDLEFLGINN
ILVVRGDPEKSQKVFTPEPDGHKHSVDLLKQIISMNQGKYLDEELLNSTPTDFSVGVAGY
PEKHCEAPNMNTDLFFLKQKINAGAEFIVTQMFFDNKKYFDFVAKCREIGINVPIIPGIK
PLSVRSQISALPFTFHIDVPEDLVKEVIKCKDNEAVRQVGVEWTIAQSKELIKSGAPAVH
YFTMGKPDNIQKIAKEVF
>A0A1X1NAM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. KB5|TrEMBL
MAAVRSLSTQPTTMGEYLATGRASFSFEFFPPKTPDGERQLWTALRQIEALHPSFVSVTY
GAGGSTREGTIRVTERIATDTTLTPIAHLTAVNHSVAELRRVIGNYAGVGVRNVLALRGD
PPGDPQGTWTAHPAGLRHADELVRLVRSVGGFCVGVAAFPDKHPRSVDFDSDARYLVGKF
DAGADYAITQFFFGADDYFRLVDRVRRLGCDKPIIPGIMPVTNVAQIVRMAQLSGAAFPP
ALASRLQAVADDPXAVRAIGVEVATELSRRLLDGGAPGLHFITLNRSSATREIYQAVR
>A0A1B8U7L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter reichenbachii|TrEMBL
MKITDHIKKADGKTLFSFEIIPPKKGNNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYID
KGNGLLDRKITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFTKEETEYVLVDCQYLGIDN
VMALRGDAMSHQKYFKPNEGGNHFAKDLVAQINDLNSGKYLHNVVEADKSSDFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFAFVDAAKKAGINVPIIPGIK
PIAVKRHLQLLPQVFRIDIPEPLITEVEKCKTNKDVRKVGIEFAIQQSKELLAAGVPVLH
YYSMGKSDNVQAIASELF
>A0A1M6SKE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caminicella sporogenes DSM 14501|TrEMBL
MIKYKFKNKRPLISFEIFPPKRDYPIDTIYNTIKALNDLRPDFISVTYGAGGSTKDTTVE
IASFIKNKYNLSSLAHLTCFTSSREDIDNILNSLKAHGIRNVLALRGDYPSGNNLSYAIS
NSYKYARDLIAHIRERGEFCIGAACYPEKHIECKSLNLDLIYLKEKVDAGVDFLITQLFF
DNEIFYRFREKTSKLNIDVPILAGILPVLNKKQIERIVSLTGCTLPPKFLRILQKYEHNP
EALKEAGIAYAVEQIVDLLSWGVDGVHIYTMNKAKTTRRILNSIKNIRGALVNECVY
>A0A366AXF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium psychrolimnae|TrEMBL
MKVTQHIEDSKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKKGGNDFAVDLVKQINQLNCGKYLHDVMDVDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A1Z8QL24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium TMED41|TrEMBL
MELSVEFFPPKTEEGFLRLSRAAEKLSSLPVEYASVTYGAGGSTREGTHSAVKILGGIFK
NAVPHISCIGSDKTTINNILKTYINSGLNHLIVLRGDLPSGFGKGGEFSNAVDXVKYIRE
QFKENFRIEVAAXPEIHPQAKNPEQDIRYFAEKVKAGANGAITQYFFNSDAYFKFVDDSH
KLGVNVPIVPGIMPITNFNXLARFSDNCGAEIPRWIRQRLSSFGDDSESIFLFGIDVVSD
LCDQLISAGVPGLHFYSMNRADAILKINENLGTFT
>A0A3D2HBG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
LQTNLVFDSDGVERWLEQLYKRDILNKAYIIIGIAPLRSLKMANHLNNEIPGVIVPDKIL
RRMEKAGNSAQEEGITIALELITDVRKMQGVNGIHLTTMGYEDVVERIIKESGITG
>A0A646JP51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus mishanensis|TrEMBL
MADTTKKPTLSFEVFPPNSEVGVEKLTNTLNQLKDLRPEFISVTCSNHKADYEKTTIDLA
KYVHNELKLPTMVHMPAAYVNKEQVSRILNQLDELDIHQVLALRGDIIDGFVPEKDFKYA
SDLTRFIKQQKPNFEVSGACYPEVHPESANRIADIKHLKEKVDAGCDQLITQLFYDNEQF
YRFQEECAIADINVPILAGIMPIINRKQALHVLENCSAHLPKKFLAILDKYKDNPVALKD
AGIAYAIDQIVDLATNDVDGVHIYTMNSASTAKHIYDNTSAFFQFDTIK
>A0A2R6H4Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QH_8_68_33|TrEMBL
MSLDTPTTADGARALLADPRFELMPFDSFGDQMVHLPDGATIAITTSPTLGLGATIDWTE
KAAAAGYEIVPHVAARYVEDDDHLDEVAGRLVEAGVDDIFVPGGDREEPAGEFESAHDLL
VALEDLGYEFDGVGITGYPEGHDFLSDETLQDAMAKKAPHATYITTQLCFDPADIVTWIE
SIRERGVELPVEVGIPGVMKYQKMVGVAQKVGVGDSISFVQKTTGLVGFIRQLVGSRGKY
EPDKLIDGLAPHATDPEYGIRGVHIYTMNQVPDTEDWRRGRLE
>A0A497QBD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MLYKSRLESLLSSNRFVVTCELGPPRGSNAQTLTEKVACVRDYCDAINVTDSACGVPSLD
TLASSVIVIQSGTEPVMQISGRDRNRIQLQSLLYGAYALGVRNVLFVTGDHLVAGFHVPA
RTVFDFDSIQGLEIARILMGGIDLAGEELDGAPQFYLGATFDPYEKPIENQLSRLRRKHD
AGAEFFQTQAIFDLSGFEDFMGRIDDLDIHVLAGVVPVRSPEAAEFMNQFVPGLSVPQKI
IDRIVCAGAGLEEEEQQEAYLEEAVSIAVETIHRVRRIDGVSGIHIMAVGCEEVVPEIVR
RAGLFPRPR
>A0A6N7WHQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eisenbergiella porci|TrEMBL
MIKELFSENKQILSFEVFPPKKEEEFANAFLVLDSLAGLQPDFISVTYGAGGSKSKKTVE
IASYIQNNLKINALAHMTCVGSGKEDIDAVTAQLKEANVNHVLALRGDRPPYMCDEQFNS
RHFPHASDLTGYLNSSTDFHIAGACYPEKHYEAKDLDSDLLHLKKKCDAGAEFLITQLFF
DNHVYYEFLDKARSTGINLPICAGIMPITSAKQLGTTVSLSGSSVPKKLADLIATYGDDP
AEMRKAGIDYAIEQILDLKIHHVDGIHIYTMNKPKVAREIVSAIR
>A0A318R3M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. AtHG25|TrEMBL
MSRLLNQLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVESIHRSYIEAGADIIQT
NTYGANFEKLRRFGLEHKVKDIHKAAVAIAKRAARPDTFILGTVGGFRSLQQEDLPLSTI
QYHAENQIDTLVEEGVDGLLFETYYDLEELTNIVTTTRRKYDIPIIAQLTASNTNYLVDG
TEINKALQQLVACGANVVGLNCHHGPHHMQRSFSHIELPETAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPQHIAYIKSSVKDLKPVKNKNVIPINRQT
NRAVTHTYKHNLTTKVKNGPTVIVELDTPKHLDTDLFFENIGKLDEANIDAVTLADNSLA
TVRVSNIAAASIIRQRYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMNYFITQPVYSKEKIKEVYEATKHLNVPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLSQFKAVKDDKEKTKALSLRLSKELIDTVHEYFNGLYIITPFQRVDYSLELAAY
SKAITQNKEAIS
>A0A7C0YAX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MLYKSRLESLLSSNRFVVTCELGPPRGSNAQTLTEKVVCVRDYCDAINVTDSACGVPSLD
TLASSVIVIQSGTEPVMQISGRDRNRIQLQSLLYGAYALGVRNVLFVTGDHLVAGFHVPA
RTVFDFDSIQGLEIARILMGGIDLAGEELDGAPQFYLGATFDPYEKPIENQLSRLRRKHD
AGAEFFQTQAIFDLSGFEDFMGRIDDLDIHVLAGVVPVRSPEAAEFMNQFVPGLSVPQKI
IDRIVCAGAGLEEEEQQEAYLEEAVSIAVETIHRVRRIDGVSGIHIMAVGCEEVVPEIVR
RAGLFPRPR
>A0A5C7UMR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKIVEHISGAKGKPLFSFELLPPVKGQSIQDVYNAIDPLMEFNPPFIDVTYHREDYIYKQ
HATGLLEKVSYRKRPGTVAICAAIMNRYKVDAVPHLICGGFTREETENALIDLQFLGIDN
VLVLRGDARKTDPSFIPTSDGHTYASDLLEQVVGMNKGIYLHEDHDKAYKTNFCVGVAGY
PEKHFEAPNMKTDFKFLKRKVDLGAEFIVTQMFFDNSKFKAFVDRCRENGITVPVIPGLK
PITSSKQIISLPKIFHIDIPEELSEAILACKSEKEVKEVGVEWMINQCKELVKIGVPVLH
FYTMSNPGPTKKIAEAIF
>A0A4D8Y721|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salvia splendens|TrEMBL
MKVIEKIQEATAANDDRVVFSFEFFPPKTEDGVENLFDKMERMVAHNPAFCDITWGAGGS
TADLTLEIVKRMQNMVCVESMMHLTCTNMPVEKIDHALTTIKSNGIQNVLALRGDPPHGQ
DKFVQVEGGFACALDLVKHMRAQYGDYFGITVAGYPEGHPDIIENGLAPEEAYQSDLAYL
KKKVDAGADVIVTQLFYDTDIFLKFVNDCRQIGIKCPIVPGIMPINNYKGFIRMTGFCKT
KGQIPSEVMEALEPIKDNEEAVRAYGIHLGTEMCKKILASGIRTLHLYTLNMEKSALAIL
ANLGLIEESKISRSLPWRRPANIFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDS
QNASYGALTDYQACIFIQNRSLLAFMRPRSRDKKLQEEWAVPLKSVEDIYEKFMSFCLGK
LRSSPWSELDGLQPETKIINENLGNINLKGFLTINSQPAVNGAKSDSPTVGWGGPGGYVY
QKAYVEFFCSPERLTALVEKCKQFPSLTYLAVNKEGTLKSNVSNNDVNAVTWGVFPAKEI
IQPTVVDPASFVVWKDEAFEIWSRVWANLYPEADPSRKVIEEVKSSYYLVSLVDNDYIHG
DLFAVFNSI
>S1QUK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus cecorum DSM 20682 = ATCC 43198|TrEMBL
MRSVGYEYNFKVSGACYPEMHPDSKNRVEDIWNLKRKVESGCQQLITQLFFDNDTFYRFQ
ESCTLSGIDVPILAGIMPIINRKQAIRLIQTCQTKVPRKFMAILEKYEYQPESLKEAGLA
YALDQIVDLVTQDADGIHLYTMNQAETARYIYQATTAIFQNLSHAS
>A0A1V5R5G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium ADurb.Bin325|TrEMBL
MNAPTPPVPAPAAPIETGLTGASSNLARVLAAGHFAVCVEIAPPVGPNVEAIQREIRTLR
GHGDAYNVTDNQSAMVHVSSLPVSIMLKQAGMEPIVQFTCRDRNRLGLQGDILGASVFGI
NTMLFLSGDHPIWGDHPQCKAVYDIDSINLIRIARMMRNNRVFENNKQIPKLAPDIFIGA
VENPFAPPYDYRPMRLAKKVVAGAQFIQTQLIYNVERFREFMRRVVDLGLHEKVAILAGV
GPMKSLRVAEYMKTEVAGMDVPDAVIERMTGLSKEDQQKAGMDICLEVAEQVRNIEGVAG
LHIMAVNWSAAVPDIVKQLGLYPRPVIEPAAAEPAGAGPAPA
>A0A2U1VY86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. TSO22-1|TrEMBL
MTGRPVPATAAAETPPPRERTVHGFEQACRSGRFVVTAEVAPPDSADPAALVERAARFRG
LVDALNITDGAGGNCHMSSVAAAAVLAAHGFDPVAQIACRDRNRIAVQGDILGAAALGVR
NVLCLTGDHGAGGDQPEAKPVFDLDAVSLLRVARDMRDRGVFASGRALETPPNLFLGATA
NPFVPPFADRAANLERKVEAGARFIQTQFCFDLHAFADFLRAVRERELHRRCALIVGVGT
LGSAKALRWMAERVPGVHVPAPVIERVARVADQKAEGKRILVETIRALAEMEGVAGVHLM
GHRNESVLADAIVESGLRTAQTAA
>H2JMC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces hygroscopicus subsp. jinggangensis (strain 5008)|TrEMBL
MDPALLDDFSLEMTGKDVPGLEEARDSIPPGTRINITFLAGEDTGTRLSAARAVKRLGFV
PVPHISARRLPSRTALEEFLAGLAADGTAGNVFVVGGDPVRPEGPYEDALAVLRTGLLRR
HGVRHVGIAGYPEGHPGIADRLLWPALTDKAAAIGADRFTGDVITQFGFDADPVLAWLEA
LRARGVHLPVRVGVPGPAGVRRLLRYAGRFGVGTSASVARKYGLSLTNLMGTAGPDRFLH
ALSERYDPARHGTVKVHFYTFGGLRTTADWIARFRHGSERISEERQTTRS
>A0A4D9C678|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salvia splendens|TrEMBL
MFSFEFFPPKTEDGVDNLFDRIERMVAYSPAFCDITWGAGGTTADLSLEIANRMQNMVCV
ETMMHLTCTNMPLSSIDHALSTINSNGIHNVLALRGDPPHGQDKFVQVKHIRAKYGDYFG
ICVAGYPEGHPEIDAGGEVIITQLFYDTDIFLKFVTDCRQIGITCPIIPGIMPINSYKAF
IRMTGFCKTKIPPEVMAALEPIKDNDEAVKAYGVQLATDMCRKILATGMRAIHLYTLNME
KSALAILTNLGLVEESKFPRSLPWRRPTNVFRATESVRPIFWYFLRPRSHEKRFLEEWVV
PLKNLEDIYEKFAKFCLGKTRSSPWSELDGLQPETKIINEQLGNINMKGFLTINSQPAVN
GAKSETSYVGWGEAGGYVYQKAYLEFFCSPASLTALINKCKAFSCLSYMAVNREGVWISN
MKNTDVNAVTWGVFPTKEIVQPTIVDPLTFMVWKDEAFELWSRGWANLYPESDPSRKLLE
EVKNSHYLVSLVDNDYVHGGLFALFRDT
>A0A3S2B6Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.006.01.1.1|TrEMBL
MIGRQRDENPAGIDLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDHGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIASGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A480A6X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dolichospermum planctonicum|TrEMBL
MQNSYSTSTLNNFRTAVAAGDFLITAEVAPPKGGDITHTIEMAATLKGRVHAVNITDGSR
AVMRMSSLVASAILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIHNILALTGDPVKA
GDHPQAKAVFDLEAVRLLQLIRNMNLGVDFNEKPLTDGKLDLFAGAAVDPQSHSWSGLQS
RFEKKIAAGAQFFQSQLITDFEILEKFMDKIACGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEEGIKIAAEQVQIARELCQGVHIMAVKREDLIAPILDLAGV
EKVS
>A0A4Y7RG41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelotomaculum schinkii|TrEMBL
MKYLSKLQAVLEGGHFAVTTEIGPPKHAGAHGLKYTAQILKDFVDAANITDNQTAIVRLS
SIAAGVHLLANALEPVAQMTCRDRNRIAIQSDLLGAYSLGIRNLLCISGDHQQFGNHPTA
KNVYDLDSIQLVNLMSRMRDEKKFFCGEEIKEYEPRFFIGAVANPFADPFEYRVDRLEKK
IKAGAQFIQTQGVFDMERFERFMELVRARGLDQRAHILAGVIPLKSWRAAKFMQTQVAGM
IVPDALVDRLKNAADPPSEGVAVCIEQIKYIRENIKGVHGVHIMAIAWEDIVPEIVKQAG
LYPRPEVVLD
>A0A8J2T7R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygosaccharomyces bailii (strain CLIB 213 / ATCC 58445 / CBS 680 / BCRC 21525 / NBRC 1098 / NCYC 1416 / NRRL Y-2227)|TrEMBL
MSIRELYDAKEGPTLSLEFFPPKTEAGKQNLLDRMQRMSALDPLFITVTWGAGGTTAEKT
LELASLAQKNLNLPVCMHLTCTNMEKHIIDDALMKCKISGIRNILALRGDPPIGQDWSDL
EAANSEFKHAVDLVRYIKTHHSGEFCVGVAAYPEGHCEGEAEGYEQDPLKDLPFLREKID
AGADFVITQLFYDVEKFLSFEVLFREQVSSEIPLIPGLMPINSFLLFNRAAKLSHASIPQ
SILQKFPPEIQSDDDTVKSIGIEVLIDIIERIYNSTSGRIKCFHFYTLNLEKAVAKIVAN
SPTLCNTLEEGEDENEEAATSEPEQDKEGDIVLEDALGVNVKNLINESRKRRRQSSNVSN
ISSELTSNRVIIGQRTQQGVGTPSRKVVVSISQGSGTLGQNATWDEFPNGRFGDSRSPAF
GEIDGYGPTIKVGNKKAYELWGSPQKIKDLQMIFIKYLEGSIDSLPWCDLGLSAETALIQ
EELIQLNDRGLLTLASQPATNGSCSTDKIFGWGPANGVVYQKAFVEMFVPRYMWENGGMK
RKLEQYGRAKLTYYVTDSRGNFETNLKPNSSNVVTWGVFSDSQVVQSTIVSEDSFKAWSD
EAFSIWLEWAKLFPRNTPTNSLLRQAHQEYCLASIVHHDYINPDELWEILLA
>A0A6D1VD14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. MDB1-18-1|TrEMBL
MSTPTDSARTRRIPFSFELYPPKTDAAASALATTIDHLAAAGPDFLSVTYGANGSSRRSS
LDVLSRILRTTNVEAMAHLTCVGSTHDEANRLIREFLDAGVRSFLALRGDPPAGTKEGEA
FLGDFGSAAELVQLIHRVQAEKSPYRETIIPGIPAARAVKPGHEKVRIAVAAFPNGHPRS
RSSAQDIDTLLAKQAAGANLGITQLFFHADHFLSFVQRAREAGVLFPILPGIMPVTSPAR
LRRIIELSGEQMPADLSIRLEIEPTKEGQREIGIQHAVDLASQVIAGGAPGLHLYAFNQH
ETVLEVLDGCGLLGAPAPVRTPTALPTIV
>A0A6M0RPP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbyaceae cyanobacterium CCMR0081|TrEMBL
MSTSNGFHSAPSLLRSAIANHKFIITAEVMPPKGGNPSHMIKMAQLLKGRVHGVNITDGS
RAVLRMSSLASAVLLKQADVEPICQMACRDRNRIALQADLMGAHALGIHNVLALTGDPVK
AGDHPKARSVFDLESVRLLRTIGQLNRGIDLNEKKLPDGPLNIFAGAAIDPQSPSWSGLQ
KRFERKVEAGAQFFQSQLISDFERLEKFMTQIAAQAQKPILAGIFLLKSAKNAAFLNRNV
PGVHIPDDIINRLATAKEPLQEGIAIAAEQIKLAQSLCQGVHIMAIRREDLIPEILDRAG
IGPVDKPKTSMETPQPLEFPVLQN
>A0A483ANN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|thiotrophic endosymbiont of Bathymodiolus puteoserpentis|TrEMBL
MKTSFEFFPPRTEKGKQTLHQVRQELSSINPEYFSVTFGALGTTQEATLETVLDIQKNDT
VAAAPHLSCIGSKKEIIIELLDQYKAANINRLVALRGDIPSGVRDIGDFHYANELVEFVK
SQYNNHFHIEVAAYPEVHPESKNRQTDLQHFADKVKAGADGAITQYFYDAEAYFKFVDEI
EKLGVSIPIIPGIMPITNYTQLVRFSNMCGAKIPNWILKKLELYQDDLDSLSTFGLEVVT
NLCQTLKEQGVNNFHFYSMNRSQPSLEIAKHL
>A0A7C3RFX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MKNLIELLKERVLVADGAMGTYLFEKGLPQDECKEYQNIKNPELVFSIHKEYVSAGAEII
ETNTFAANSVKLSKFNLEDKLKEINYEGVRIAREAGGKDVFVAGSVGPLGVMLRPYGIFT
FNDMVKVFKEQISILVSAGVDLIIIETISSLLEARAALLASKSISDLPVIVSMTFLADGK
TKFGDDITRSLNELKEIGADIVGANCTVGPQETAEIVIPYLKESPNLFSVMPNAGYPTIV
RGKTIYLSSPAYFKEYAEIFLENGANIIGSCCGTNPTHTRAIAEVVKGEKPRKRKKITYV
EIIEEERREEKVELKSRFREKIGKEMVLTVEIDPPKGHNCNEVIEISRKLMAYGVDALNV
AENPMARMRMSSIALAHLIQEKVGIETILHFTCRDRNLLGIQSELLGASVLGIKNILALR
GDPAEIGDFPKATSVYDIDTVGLVRLIKEFNKGRDMGGNPIGSPTSFLVGVASNPSSPDL
SAELKRLEEKVNAGADFVLTQPQYDLSNIENFLKETEKFNIPIIVGVMPLKSARHAEFLH
NEVPGIRIPEEIRERLKKARQEEQGRIGLEIAIDFIRRIKGEVSGIYLIPPPQGFELIFE
IISQTMENSERGI
>A0A6S5JSI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSASIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A150W147|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC04657|TrEMBL
MALGTASVRSDRARTVRDILASGGTSYSFEFYAPRTEKGEQSLWRAMRRVEAVGPSFVSV
TYGAGGTTRGGTVKATQKIASDSTLTPVAHLTAVGQSVAELRNILGQYADAGIRNMLALR
GDPPGDPLGEWIEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVVKAGCETPIIPEVMPVVNVKTLDRLPQLSNAAF
PARVKERILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>F2NGU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2)|TrEMBL
MHLQEKLEFKKFIILAEMEPPKGTDVSSLVANATNVKGRVDAFVAPEMNNAVMKMSSLGT
ALLLQSKGFETVMQVCCRDRNRLALQADLLAAQALGIPNVMAVTGEDISYGDHHRARAVN
DLDLLELLAAIQTLQSGRDLAGIELQGAPRFLVGASLNVGKSGGALEAELAELDKKMAVG
AQFFITSPIFALKVLDQFRKRLGNRPAKIIPTVMLLKSVGMARYIDRHLEQIHIPAGLIE
RIHKAPDRVRECIMIAAELIAGLKDEGYSGVQISTLGWEDRLPAILAAARA
>A0A4V0HX36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmataceae bacterium|TrEMBL
MHIQDIFAGHRTTFSFEFFPPATDAASEELFRNIASLQELQPSFVSVTYGAGGSTRDRTH
DLIVRIQKETALVAVSHLTCVCHDLAEMTAILDRYAASGIKNILALSGDPPRTMPNYDRS
KDAFHYAEELVRFVRGRTNAPDPRGFGVGVAGFPEGHPGCPNRLLEMDYLKRKVDAGADY
ICTQLFFENRDFYDFRERCDLAGIKVPIVAGIMPVGTKAGMVRMAQLALGARVPAKLLRA
VSRCADDEAVARVGTSWATEQCADLLHNGVRGIHFYTLNKSDATRQIYQNLGVADSAALR
A
>A0A2S6ZIH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. arracaciae|TrEMBL
MDPDTPSLAGTITEAYSLEVSAKHIAGLAAAAPRITRGATIAIPYLPNQDDDARLAAARM
VRALGFQPMPHLSARRIASREQLHAFVSRAVDDAGVERCLVIAGDPPTPLGPFPDSLSLI
DTGIFERSGIRTIAVAGHPEGHPSMPAADRWEVLQRKCRSIAERGMVPLIVTQFAFDADI
VLTWLQALRAHGIAHPVRVGVPGPAGVAVLARYAASCGVGACASMLSKYGISLGKLLGTA
GPDRFVERLATGLTDAHGEVRMHFYPFGGIAQTVAWVEQYRSLTTRGRAD
>A0A2S6ZST8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. arracaciae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWISKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1E5QY53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacterium sp. IPPAS B-1200|TrEMBL
MGNNLSKLQKAIALKQFLITAEITPPKGGNPERMLEVAKVLKNRVHGVNITDGSRAVLRM
SSVAASALLLRESIEPICQVTGRDRNSIGLQADLMGAYGLGIRNILALTGDPIKAGDHPQ
AKAVFELESIRLLNLIDKLNQGFDINNKALSDGKLELFAGAAVDPQSKSWSGLQRRFEKK
IEAGAQFFQSQLITDFEKLDKFMTQIAIKGDRPILAGIFLLKSAKNALFINKYVPGVEIP
EHIIKRLEKAQNPLQEGIKIAAEQVKMAQDICQGVHLMAVKKEELIPEILDLAGIKPLQ
>A0A524I3W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MDKIFHVELQTPKRSSEDIEKDLRVFEEKYRKVVEAGWIVCITDNPMGLLSYGAMETIDL
MGLPVHPEQLMVHLNTFHTKKELDEVLAAFKTAGGKHLLIVSGDGSQRLHRLEPAEVGIE
ALTVTSVELLRYIDREFPGQFTCGVAFNPYEPQDAELEKMRRKVDAGASFIITQPIIGRD
DRLTGLGPFRLPVTLDAWMSKKLHLLSECVGHEIPEGTPYDPMENLRELRRNYPGYGLYL
AILGFKTQYPLLPEIWK
>A0A165PNX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudovibrio sp. W74|TrEMBL
MSEHSIDRRFRLNGASDISVSFEFFPPKSEKMEQQLWSSIKRLEPLAPNFVSVTYGAGGS
TRERTHSTVSRIVNETALKPAAHLTCVDATKEEVNEVIRAYWDAGVRHIVALRGDPAAGL
GEQYHPHEGGYQSTADLVASIRSIGDFEVSVSAYPEKHPESPSWETELDVLKAKVDAGAT
RAITQFFFDNDHYFRYVDRVRAAGITIPIIPGIVPVTSFKGISGFAKKTGASVPGWLAHR
FDGLDDDPRTRELVAAAVAAEQVMSLADDGVEDFHFYTMNKADLVYAICHMLGLRAKQDV
KASVAA
>A0A2W6Y2X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chelatococcus sp|TrEMBL
MNAFRPSRHGSRRPRVSFEFFPPKTEEMEVALWESVRRLEPLQPSFVSVTYGAGGSTRER
THATVKRMVEETSLKPAAHLTCVSASKAEVDEVIRSYWDAGVRHVVALRGDPAGGLGTVY
EPHPDGYHQTSDLVAGLKRIGDFEVTVSAYPEKHPEAASLEADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRAAGIEIPILPGIVPVQNFKQTANFARKTGASVPQWLADRFEGL
EDDAATRRLVAAAVCAEQVLDLIDRGAPDLHFYTMNKADLVYAICHLVGLKPEKAAAQAA
AAE
>A0A2M6ZK37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG07_land_8_20_14_0_80_60_11|TrEMBL
MSKLRETLEAGAFPVVVELKPPKGAGVDEMLAVVKALAGRVTAFSLPDNEHARMRLAAVA
AARLVQEAGGEALVHLTCRDRNRLALESDLLGAASLGLENLLLVSGDYVTLGDHPQAKPV
YDADSVQLLQIARGLMDGHDSAGLALTGAPAFFLGAVVIPEAEPLPPQLIKFEKKLAAGA
QFFITPAVFDLDKLRRFREHLPETPVKLLVSVKVLGADEVAQAAAGQWRKVYSLPPNLVN
DLAGKEPEDILAMGVKAASRLVQQIKQEKLADGVYLKAKGRTDLFTKILEAAGL
>A0A258DSN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 32-66-8|TrEMBL
MSAPVRASRELGKAPVNVSFEFFPPKTEEMERNLWSAIGRLAPLSPSFVSVTYGAGGSTR
ERTHATVARLVRETALAPAAHLTCVAASRAEIDDVVRAYAQAGVKHIVALRGDPTTGVGT
AYEPHPDGYAHACDLVAGIKRLGDFEVSVSAYPEKHPESASIDADIDYLKRKVDAGATRA
ITQFFFENDVYFRYLDKVRAAGIDIPVLPGIVPVQNFKQTANFARKTGASVPQWLADRFE
GLEEDAATRRLVAAAVCAEQVLDLIDRGVGDLHFYTMNKADLVYAICHLAGVKPERGEAQ
AAAAE
>A0A4Y8C2N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. US18a|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITHILQKCKENNLHQILALRGDICENLKKSKDFSYASDLISF
IKKQKYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALVGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHT
>A0A7G4YWH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodotorula paludigena|TrEMBL
PDPRSATALTSSSPPTAALADLDFRLSSRPNQPTMSGTSTPELRQPQSQKVTSRIAQLAP
SQPFYTFEVFPPKTDAGLANLVDRVDRMSALDPTWMHVTWGAGGSTQERSLELSGAIQGM
GLETCLHLTCTNLEEGVLERTLQRAKDLGVVNLLALRGDPPRGEEYWTASSDEFQHAIDL
VRYIRKEYGNEFCIGVAGYPEGHADSADKLADIEHLYEKQEAGADFVVTQLFYDVEVFKK
WYKACRDRGITIPILPGIMPIQNYLSFRRMTNLCGTHIPEDILSDLERIQHDDAAVKDYG
VQLAVKMMRALFEHGIRGYHLCTLNLEKSVTRVLELLEWVEPGATRTRPAVQKALAANGA
PLPKVVNSLRPAPAASPSVAGADIARKDSPASWDEFPNGRFGDARSPAYGEMDGYGVSLK
LPPGEAIRLWGEPTTLADISRVFSSYLRGSIQSNPWSEEPLRAETAAISSRLLEMNDERH
WWTVGSQPAVDGAPSADAVHGFGPKGGYVYQKAFVEFFLTADELDELERRSAADERARID
AGEGDDGLVKWFAGNMRGEFRSNLGKGDVNAVTWGVFGGKEIVTTTLIEEMSFRAWCEEA
FALWKEWSLLYAAASPARGFIRSIAESRWLVSVVHHDYKDQDGLWRWLLSLKTSTTEQA
>A0A7J4IDV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MPYRSNLEKRLSEGHFVVTAEIGPPKSADPLKIRDKALLLEGCADAFNVTDNQTAVVRMS
SFAGSVLILQMEMEPIMQMTCRDRNRISLQSDVLGATALGVRNILCLTGDHQSFGNHPAA
KGVFDVDSLQLLQIIQKMRDEGIFQSGDSLLGIRPCVFLGAAANPYADPFEIQVDRVRKK
IDAGAQFIQTQSVYNIEKFSAWMDDVCSQGLDKKVHIIAGVTPLKSVKMAERMKFHVPGT
DVPDFVYERMKNASDPAKEGYQIALKTIRELKQLKGIHGIHITALFWEEIIPSLVKESGL
QSPR
>A0A3A5JHP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halococcus sp. IIIV-5B|TrEMBL
MSVESHSSTAAEVTDELLTGPRFELMPFESFEGQLEHLPEGATIAITTSPQLGLDATVEQ
AEMAAARGFDVSPHIAARYVRDEDHLTEIARRLTEAGVTDIFVPGGDREEPAGEFDSAYE
LLTALSDIEYSFEEVGITGYPEGHDFLSDRVLAEAMEKKAPFATYIVTQLCYDPDAVIEW
IEEVRGRGVDLPIEVGIPGVMKYQRLLSISQKVGVGDSVRFLKKTTGIVGFVRQLVESRG
KYTPDDLIEGLTPYATDPEYGIRGVHIYTFNQTSDTESWRWGALNQ
>A0A844YRD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteraurantiacibacter buctensis|TrEMBL
MSYAAIHPNWEQAPANMVDGYSLEMTAKEIEGLKEAAHLIRPGTQVAVTFLPGEELSQRI
EAAVLVRELGFEPIVHLSARRIESQEQLDWYLGEITTKAQVKRVFIIAGDPPEPEGPYSD
SLQIIETGLLEKHGIEIVGVGGHPEGHPNNTPAELWVWMEKKLAAIRAHGMVPLVVTQFA
FDDDAIVQWLSEMRARGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGISLTN
LIGSAGPDKLVNSLDKKLGAEHGRVRLHLYPFGALTASAEWINDYDKKHS
>A0A7G2U946|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp|TrEMBL
MTTPAISFEFFPPKTLEASFRLWDTVQTLAPLEPRFVSVTYGAGGTTRQLTREAVETLHK
SAGLQVAAHXTCVDASRSETLAIADDXARAGVTXIVALRGDPPKGSGGXRPHPDGFEDSC
ALISALADTGRFNIRVGAYPERHPEAADDAADVDWLKRKIDAGASEAITQFFFEAETFLR
FRDRCAKAGIDAPIVPGILPIENWSNTRRFATAXGTGVPQWLDXAFDKATRDGREDLLAT
ALATELCSDLLEEGVETLHFYTLNRPELTRDICHALGVTPKVKLRDVA
>A0A484NVI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|plant metagenome|TrEMBL
MEVSAKDIPALTAVAPRLPPASTISIPYLAGEGNAARLAAARAVRELGFEPMPHISARRV
ASLAELQAFVARAAAEAGVERCFVIAGDPSTPKGPFPDSFSLIDTGVFERAGIKALGVGG
HPEGHPVMSVADRWEVLERKCRGIEGRGMAPSIVTQFVFDADVVLTWLAALRARGIAHPV
RVGVPGPAGVAVLARYAAMCGVGACASMLAKYGISIGKLLGTAGPDRFVDRLAAGLTPAH
GTVSLHFFPFGGIAQSVGWIEQYRATRKQNTR
>A0A7J4EGD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MKISVILNETKETRFSLEVFPPKTGVSERIPIQRHLSNIFETVEHLIKYDPVFVSVTYNP
EGKTKTTSIPLAAIIKQKYKVEAVAHLTCISTPREELSKTLDVIDYFDIENILALRGDIP
DGSSPTGELRHASDLVEEITKHEKSFCIGVACYPEGHPECVTEEGGWDLEKDLLHFKAKV
DKGAGFAITQLFFDNNVFFSFVKKAREVGVKVPIIPGIMPIRSYNILNVVKRLGNISMPY
SLVKKLEDNRDNKAEIIEIGVEQAVKQCRGLMNKVPCIHFYTMDRWMSVDRILKELS
>A0A355UTS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium UBA8530|TrEMBL
MSRDFRKVLEEGRIHVFDGAMGTMIYQRGVFINRSYDELCLTMPDMIRDIHRAYLEAGCE
IIETNSFGANRPHLAAHGLQEKVFIINQRAAEIAREAGGEQAFVAGSVGPLGIRLKPYGS
VSAKEARAFFKESIEGLVAGGIDLLLLETFSDLHEMRQAIRAAQETCHLPIVAQMTIQVD
GKTTFGHSPEDIVKALDRWGADVIGLNCSVGPAAMLEAIERMRPLTKKPLSAQPNAGMPR
EIEGRKMYMSSPEYMAEYAKRLIQKGVRFVGGCCGTTPEHIRLIRDAARALSPRRTAELI
LVEDRGDARQESKRLTPVPAEQRSQFAAKLLGGEFVSSVEILPPRGADISSLLQGVKSIK
EAGVDVVNVPDGPRAQSRMGVLATSHLIEREVGIEAVMHYACRDRNILGMQSDLLGAAAL
GLRNLLLVTGDPPKMGPYPLATAVFDIDSIGLVSMVNNLNHGLDLGRNPIGKPTAFFLGV
GVNPCALDLEQELRRFAQKIEAGAQYAITQPVFDPRQLEIFLERTESFRIPIIAGIWPLV
SFRNAEFLSSEVAGVVIPHSVMERMRKIGDPEQATLEGIMIAREMLAEVRGGISGVQVSA
PLGKIPLALEVFRK
>A0A484RJK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|plant metagenome|TrEMBL
MDVAVARRPPLHDCYSMEVSAKDIPALTAVAPRLPPASTISIPYLAGEGNAARLAAARAV
RELGFEPMPHISARRVASLSELQAFVARAAAEAGVERCFVIAGDPSTPKGPFPDSFSLID
TGVFERAGIKALGVGGHPEGHPVMSVADRWEVLERKCRGIEGRGMAPSIVTQFVFDADVV
LTWLEALRARGIAHPVRVGVPGPAGVAVLARYAAMCGVGACASMLAKYGISIGKLLGTAG
PDRFVDRLAAGLTPAHGTVSLHFFPFGGIAQSVGWIEQYRATRKQNTR
>A0A1N6JN00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWB11|TrEMBL
MKIIDILKQDKMSLSFEVFPPKKETSFENVKAATEAIAKLNPAFMSVTYGAGGGVSQYTL
EIAKNLKYNFNIPMLAHLTCISSTKETIHQRIEDMKAAGIKNVMALRGDLTPELIANGRG
DCDYHHAVELIRELKAADADFCIGAACYPEKHPESPNQAEDIKHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPDAMKQAGIIYATDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFAG
>A0A0A8WX69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp. OR-1|TrEMBL
MPSPLQAKLAADSFVITAEVCPPKGSDCAQFLNVSRALSDQVDAINITDNQGANMRISSL
AASALLIRDGIEPIFQLTCRDRNRLALQSDLLGAAALGVTNILALTGDYISFGDHPQGKP
VFDLDSVQLLRTIDGLNNGKDMNGHQLSGSTTFFCGAAAAPDAEPFELSLIKLEKKVAAG
ARFFQTQAIFDLKKLERFKKATRHLQVKTIAGILLLKSAGMARYINKHIPGLTIPDIIID
QLAGAPDPAMKGLEIACRLAVEAAPLCDGIHIMAMGREELIPNIVETLKR
>G0L234|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zobellia galactanivorans (strain DSM 12802 / CCUG 47099 / CIP 106680 / NCIMB 13871 / Dsij)|TrEMBL
MKITDHIKNAKGKTLFSFEIIPPVKGHQIQQLYDNIDPLMDFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYNVDTVPHVLCGGFTREETEYLLVDCHYLGIDNI
MALRGDAMKDEKYFQPTKGGHAYAVDLVKQVHELNCGNYLHDTVETDNCADFCIGVAGYP
EKHLEAPSLKSDLKRLKEKVDAGADYVVTQMFFDNKKYFQFVEEAKKMGINIPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVDDCASNKEVRQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAEEIF
>A0A2A9FPZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. LV10R520-4|TrEMBL
MESQKQFKRRFSFEFFPPKTEQGKIKLQGVRDELAAVNPDFFSVTFGAGGSTRDRTLETV
FSLHQQGISTAPHLSCVGGTRAEISELLDTYKEKGINRIVALRGDLPSGMGAAGELRYAN
ELVSFIREHSGDYFNLEVAAYPEFHPQARSAEEDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKSGITIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSVSIRQ
FGEEVVTRMCEKLLKAGAPGLHFYTLNQVEPSLGIWKNLGLGEREKISF
>A0A0M1KD54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLISFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
AALCERLMAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A3M1NV16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MQVIEAIKKTKSFVLSLEITPPDKGTSIDELFQTLDGLMQFNPQFINVTYHQPHVVYEEK
DGVIYRIPKRKKPGTVGICAAITNRYQVETVPHFICGGFSKYETEDALIDLHYLGIKNIL
ALRGDPAVGERTFIPHKDGHRYASELVRQISNMNKGIYLEELENAQPTNFCIGVAGYPEK
HFEAPNFERDLQNLKHKVDQGAHYIITQMFFDFQVFKNFVERAREIGITVPIIPGIKPLT
TVRQLSSIPRNFHCTIPHHIVEDMENARTKEEARKIGIKKVVELCQQLLDYKCPGLHIYT
MGKGQSTADLLKALFG
>A0A2I8SEY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii complex sp. CFNIH3|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIARDYWQNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A416TK90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. AF19-1|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A539DNH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halothiobacillaceae bacterium|TrEMBL
MHSQKKFQPHFSLEFFPPKTAEGASKLRQTRAMLAQLNPAYISVTFGAGGSTQEGTLDTV
TEIQASGTPAAPHLSCIGSTKESLRHILATYRERNITRIVALRGDMPSGMRSSGELRHAN
ELVEFIRAETGDLFSIEVAAYPEFHPQAASAAEDLKNFQRKVAAGANSAITQYFYNSDAY
FRFVESCAALGLDIPRIAACLWPGCGDRAVSSATRPRGTGTPLLHHEPGGTNYHDLAQFR
FIKPGVAPHRMRVPRLYLDQPLALQQAVLLDKEASHYLTRVLRLRERAKVILFNGAGGEY
LATLTATAPNATLLPEYFTEPLSESPLILHLAQGISRGERMHYAIQKAVELGVSTIQPIV
SRYCEVKLDQERSSKRQLHWQ
>A0A6N1AQ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum oryzae|TrEMBL
MTAPISSLPSISFEFFPPKSEKMEQSLWQSIRRLAPLSPSFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGRYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDAYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPAKLAETFEGLDD
DPETRQLVAATVAAEQCQALQAQGVNDFHFYTLNRSDLTIAICRMLGVKAKAAPAAAAVA
G
>A0A1J5DYB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG2_30_66_27|TrEMBL
MKKSPLIFDGAVGTMIYDHGVFINTCYDELCLTNPKLILRIHRDYVEAGAEVIETNTFGA
NPIRLKPYGLAEKTEAINRAGVRLAREAAGDEVFVAGSVGPCTESRQRMPDAFAAEVEAA
FRAQMGALAAEGVDLFLLETFSNLNELQLAARVAKEFGEPVLASFVLNDRGETALGMRAE
TMASALSGDANVDIVGINCGTGPSGAFDALQAILPHTGKPVVVMPNAGMPREISGRVIYL
TSPEYFTEYAKKYIELGVRGVGGCCGTTPAHIRMAARAVKPLRVGKRRFEVKPLLRQESL
VYAVPTERKSRLAAKMCAGEKVTSVELVPPKSSDMTALLDRARKCAEAGVDAINIPDGPR
ASARVSPMISALTISREVGIETILHYCCRDRNLIGMQSDLLGGYAAKLANFLIITGDPPK
LGEYPDVTGVFDVDSIGLVQVAANLNRGLDIGGNPIDPPTGLFIGVGANPCAVDLSREIE
RYFRKIDAGAEFAITQPVFDPEALLRFLDRVDGYRRRIPVLAGVWPLVSFKNAEFMNNEV
PGVVVPKEILERMSRCRTREDGRKAGIEIARGIIERISDRVSGFQVSAPMGHVETALAVL
GKST
>A0A1Y4T9F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. An122|TrEMBL
MKNARDILRDRVLVFDGGMGTYYKGRPGLECEQANLADPEGILAVHWEYLDAGAEAIKTN
TFGLPRMAAAGLDNWQELAAAGWRLACRAAEGTGAAVFADLGPAPATDAAPAAQTYRAAA
QVFLDLGAENFLFETLSTDEGVAEAAAFIKERRPEAFILVSFAALPDGYTREGRSCRELA
AHMARCGHVDAVGLNCLLAPSAMASVLPAVTGCGLPVSAMPNGGYPLVTRSRVVYQGRPD
YFARELCRIRQRGGVILGGCCGTTPAHIAALRQALESTPMPIAASAPAADVPAETPLLTP
ADPFLQKLARGEKVIAVELDSPKDADLSGYVEGARRLQAAGADAVTVADCPIARARVDSS
LTACKLRRELGMVALPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLARYIHSLAGPGEALPGMTVFGALNLNARNFDVELRRAQEKQASGMAGFLT
QPVLSEAAVDNLKAARAALPDAKILAGILPVVSQRNALYMENEINGIHVDEAIIRRYEGA
DRAQGEALGLEISLEMARAAAPYADGFYLMTPFNRVALMERLIAALKQEAL
>A0A6I4IE47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter aquatilis|TrEMBL
MKITDHIANANGKTLFSFELLPPIKGQSMDGIYKAIDPLMEFKPPFIDVTSSREDLFYKE
TADGSIQKATYRKRPGTVAVCAAIQHKYKVDTVPHLICGGFTKEETEYALIDLQFLGIDN
VLVLRGDARKTDSGFIPTPGGHCYATELLEQVTNMNNGVYLHEYQDTSYKTDFCIGVAAY
PEKHFEAPNLKTDFKYLRQKVDGGANFIVTQMFFDNSKFKAFVNQCRENGINVPIIPGLK
PITTAKQLINLPKIFHIDIPEDLCDAIHDCKNDKEVKEVGIEWMINQCKELVDFGVPVLH
FYTMGNPEPTKRIAQAIF
>A0A1F1BW17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. HMSC078E07|TrEMBL
MSRLLNHLKNNVLVADGAMGTILYSEGLDTCPEAYNLTHPNKVERIHRSYIEAGADVIQT
NTYGANFEKLKVFGLEHKVKEIHKAAVQIAKRAANKETFILGTVGGFRGIKQEDLSLSTI
QYHTDNQIDTLIEEGVDGLLFETYYDLDELTSVITATRQKYDIPIIAQLTASNTNYLVDG
TEINEALKHLIECGANVVGLNCHHGPHHMQRSFSHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAKYFGDVAQELINEGVRLIGGCCGTTPEHISYIKESVKNLKPIKNKKVIPIHRTI
NTNAKRTLKQNLTSKVKQRPTVIVELDTPKHLDTELFFENIGKLDEAHIDAVTLADNSLA
TVRISNIAAASLIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLIGVSEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINVDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMSYFITQPVYSKEKIKEVYEATKHLDTPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYLITPFQRIDYSLELAAY
SKAITQNKEAIL
>A0A7J3U7W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon|TrEMBL
MKITDILGESTGTRFSLEVFPPKTGVPETIPIQRHLSNIFDTVEHLIKYDPVFVSVTYNP
EGKTRTTSIPLAAIIKQKYKVEAVAHLTCISTPKKELSKTLDVIDYFDIENILALRGDLP
DDSMEIKGLKHASDLVEEIKKHSKRFCIGVACYPEGHPECVTKDGKKDLKRDLLNFKAKV
DKGADFAVTQLFFDNRVFFDFVEKTKKIGVKIPIIPGIMPIRSYNTLNIVKRLGNISMPD
SLVKKLEDNRDDKKEIIEIGVNYAVKQCRELMSKVPCIHFYTMDRWVSVDRILKELI
>A0A6I4TZ63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceibacterium xixiisoli|TrEMBL
MSYAAIHPDWEKPRSNMVDGYSLEMTAKETAGLREAASAIRPGTQIAVTFLPGEEIEQRV
EAAVLVRELGFEPIVHLSARRILSEEQLENYLRDITTKAGVKRVFIIAGDPPEAEGPYSD
SLQIIETGLLEKYGIEIVGVGGHPEGHPNNTKDQLWDWMERKIAAVRAHGMTPLVVTQFA
FDDDAIVEWVGEMRARGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGVSITN
LLGNAGPDKLVNSLNELLGDQHGRVRLHLYPFGALKASADWINSYDAKH
>A0A315TBU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. H-02-3|TrEMBL
MSPPSLIDPHPNLAGPAPVALSYELFPPRSAAAAESLWTTIGELEATDPDYVSVTYGASG
SNRSTAVELINRLVQETTLRPLAHLTCVGNSPEELAEIIGELLDVGVRGILALRGDQPKD
GATPPPGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHAEQYADLLTRARRAGVTIPIIPGVMPLTSLRRLARLGELTGVE
PAPELIERLAAADTDAERTRIGVSATVDLANAALDAGAPGIHLYTFNEHAAALDVLDKLA
LPRPRSGNRQGGNRHSGGRINASRRAAARQLAS
>A0A2K1ECK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. SAORIC-644|TrEMBL
MEAPLFSGLPGDIEVSFEFFPPKSDKMGETLWQSVETLAPLGPRFASVTYGAGGSTRERT
HQQVVRIQNEAGIPAAAHLTCVEATREQVDDVARHYWEEGIRHIVALRGDPPDGQSRYSA
HPGGYANAAELIAGLKKVADFEISVAAYPEVHPDSSDRKADLDNLKAKFDAGATRAITQF
FFEPECFFDFRDQAAAAGIKGEIVPGIMPVMSFAAVQRMSGLCGTAIPHWMEGLFEGLDE
RPEARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKA
>J3TEM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Carsonella ruddii PC isolate NHV|TrEMBL
MKNISFELFPCNNIKDLSILINYLKNKKPSFISVTFGKIKNLKFVENLQKKFSVKIIPHL
ICDNIFNIINNIIYFIKIKIFTFLIITGDKNKNNSINYISLIRILFGYLIKIITGCYFEN
HKFSDNFKNEILFHYKKNKKGVNINISQFFYNFNIINYYIKVIKKTGINKNLILGIILKK
EIKDILNFVNLCKIDIPLWLIKNYYEFNIELFFIKNLKKYKNLHFYTFNNISLVKNYFK
>A0A257LJI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium PBB5|TrEMBL
MAGAPLPISIEFFPPNTPVGAEKLKTVVQDLSVLKPEFFSVTYGAGGATRDKTLATVRDI
AAMGHEAAPHLSCVGSTREGIAEILATYRAQGIRRIVALRGDLPSGTAVAGEFRYASELV
SFIRETQGADWHIEVAAYPEYHPEQRYARKDLQHFAAKCQAGADSAITQFFFNPDAYFHF
VDEVRALGVTQPIVPGIMPIHSFARIVQFAARDGIEIPRWVMLKMEGYLDDAASIRAFGI
EVIARLCERLAAGGAPAIHFYALNQSALTLEICRKLGWA
>A0A4P7RXI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. PAMC25046|TrEMBL
MTSNLNSLAEARRAAASPLFANLEGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLAPSFV
SVTYGAGGSTRERTHATVARIAAESRVPPAAHLTCVEASRVEIDEVAHAYWDAGVRHIVA
LRGDVPGGEPYRPHPDGYANAIELVAGLKAIAPFDISVAAYPEVHPDADCPQADLDNLKR
KLDAGATRAITQFFFSPDSFLRFRDAAAAAGIDAPIIPGILPVSNVSQTRRMANMCGTAI
PAWMVSLFDGLDDHPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVSTVKDQAA
>A0A417TC63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM04-7|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPTLSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPALCIGAACYPEGHVESVNKTVDIDHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A4R2SEA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PP-CC-2G-626|TrEMBL
MSGFPSASGDLLPGHSSRGRLEQVLRRGEFAVTAELNPPDSADPEEVYARAAVFEGWVDG
INAVDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQGDVLGAAAMGVANILC
LTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDHAKFLSGRKLTAPPRVFLGAAINPFA
PPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFRAYMEKVRDLGLHEHCHILVGVGPMASA
RTARWIRSNVPGVHIPDAIIARLEGATDQKKEGKQICIDIINEVKEIKGVSGIHVMAYRQ
EEYVAEIVHESGVLKGRRPWRREQDPADAGVAERLDAARGGEMQDQESLAETAAKRPH
>A0A444NU45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MALKNEVRGRNIRVSFEFFPPKSEEMEGQLWHTVSQLQDWDPDFVSVTYGAGGTTRAPTL
STVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRPRRETKSAGA
AA
>A0A1I5ADA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Izhakiella capsodis|TrEMBL
MSFFHANQREALNQSLAELCGRFNVSFEFFPPRTKEMEDTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKDIKDRTGLDAAPHLTCVDASRDELKTIAEDYWRSGIRHIVALRGD
LPPGSGKPGMYACDLVSLLNEVGDFDISVAAYPEVHPEARSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEVVPGILPVSNFKQLQRFATLTNVRVPGWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVSAA
>A0A4V6KKB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia fonticola|TrEMBL
MSFYHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGGGKPEMYATDLVTLLKDVGDFDISVAAYPEVHPEAKSAQSDLTQP
>A0A291EH32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia pickettii|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRENIRSILNTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVAF
IRQETGDAFHIEVAAYPEYHPQSRSPRHDLDNFARKVKAGANSAITQYFFNADAYFQFVE
DARKVGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLESFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNTATATRAIWQRLGL
>A0A2W7R357|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cereibacter changlensis|TrEMBL
MTQPRISFEFFPPQTLDASFRLWETVQMLAPLKPSFASVTYGAGGTTRKLTHEAVTTIGK
NYGLNVAAHLTCVDATRAETLEIAAAYAEAGVTEIVALRGDAPKGAERFTAHPEGFANSI
ELIEALAATGKFTLRVGAYPEPHPEAADPLADVRWLKRKIDAGASSAITQFFFEAETFLR
FRDACVAEGITAPIIPGILPIENWGGVKKFAQRCGTAVPQWLDDAFDHAKRDGREDLLSV
ALCTELCDTLLSEGVEDLHFYTLNRPHLTREVCHALGVVPEVALQNVA
>A0A838AXU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium neociceri|TrEMBL
MIARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEVPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLDRILHDEITETQVDMVK
TAH
>A0A836P193|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas vasicola pv. vasculorum NCPPB 890|TrEMBL
MSTDTPSLANTIADAYSLEVSVKDIGALTKAAPRMLPGSTMFIPYLPGQNDAARLAAAQM
VRGLGFEPMPHLSARRMTSLDELQAFVARLVDEAGVTRCFVIAGDPSTPKGPFADSLSLI
DTGVFERAGIRTIGVAGHPEGHPIMHTAEQWDVLERKCRSIEERGMAAVIVTQFGFDADM
VVTWVEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGA
>A0A8J2Z7L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldovatus sediminis|TrEMBL
MDIPPSTAAPGGAAPGTLQRWLTGPRFAGLPAPAEAAPRLSFEFFPPRTEALEQQLWAAI
RRLEPLRPRFVSVTYGAGGSTQERTHATVARILRETALTPAAHLTCVGASRAEVDAVARR
YWEAGVRHIVALRGDPPAGQARYEPHPEGYAFAADLVAGLARVAPFEISVAAYPETHPAA
LSPEQDLDNLKRKIDAGATRAITQYFFDTDVFLRFLDRCLAAGITVPVVPGILPVSNFAQ
VRKFSAMCGASIPAWMPRLFEGLEEDPETRRMVAAVVAAEQVRLLQANGVDEFHFYTLNR
ADLTYAIAHLLGARPAPAG
>W7CUZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria riparia FSL S10-1204|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPITSKVVHPIV
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDMEKAAQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQTGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQDITEQIISQN
>A0A1T1J5I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. MF4642|TrEMBL
MSLLAQYFAQQQFCVLVEYLSSHQAQWPVKAQFAGFPAAMTLADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDAKTQGQKNLLLLTGDKLKQHHYSHDLEPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMAAL
QDAHAFLVQHQYAQKMLACVMPLTLARAKFMLKHKVAGIVITPHMLQVLQQEKEQGLSDR
VYVRCALQILMCRHLGFAGVHLSACHQPEEQSFLERYIEEYRHLSFAECEQLWNTLWQVQ
TGTEFHPKLAYYSRPATSSQIIKYQHLHLMHDALFESKLAKGMGRFIFNFNVWDRSRAKQ
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTKILKEKLIPTVSIAVRGTSSWKNWYVEAAS
>A0A6I6ERF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium bovifaecis|TrEMBL
MHIKNIFSNKKPIISFEVFPPHKDYSIDSIYKTIDELAPLNPDYISVTYGAGGNSVGKNK
TVEIASIIKNKYDIEALAHLTCIGSTKYEVNEVLKALNENNINNVLALRGDLPQDPSFKF
PSRLHFRYAVDLIGEIKKQGDFCIGAACYPEGHIECESFNKDIKNLRKKVDSGADFLISQ
LFFDNNFFYNFRGKANAEGIKVPIQVGIMPVINSRQIRRIASLCGAHIPEKFEKIVDKYI
DKSEALKDAGIAYATEQIIDLLSSGVDGIHIYTMNNPEVAKRIVSNIFSIVKALNSSIAV
>A0A0R2J8I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carnobacterium maltaromaticum|TrEMBL
MGLKEVLGTKLLIADGAMGTLLYQYGIDRSHEELNCSHPEAILKIHQDYLAAGADIIQTN
TYGANYIKLARYGLEDQVQKINRAGITLAKEARGDKEAFILGTIGGIYGAVDTKIHDPGM
EEISRSFKEQLYCLLLGGVDGILLETYYDLNELKTVLAIAREATDIPIIANVSIHEVGIL
ANGQSLATALEELSDLGANVVGTNCLLGPHFMAQSFESVPLIPGKVLAAYPNASFPTMEN
GRIVYQKETDYFKLFGELFRKEGVGLIGGCCGTTPEHIAAYREGLTTLDLVTQKKVKALT
TYRFQAKQETGKERLLDKVQREYTVLVELDPPRTFNTTAFFKGAARLKEVGVDAITLSDN
SLASARISNMALSAMLKYEYDIQPLVHLTTRDHNLIGLNSQIMGFHKLGIQDVLAVTGDP
AKVGDFPGASSVFDVSSFELIKLIKNFNQGIAYTGKNLREKTNFQVAAAFNPNIPRLERA
GRLLKKKQEAGADYFITQPIFDSEKVKILKEVMKTAGVTIPIFIGVIPLVSSRNAEFLHN
EVPGILLTDETRERMRMAEEEGRGLEVGMTIAKELIDEICQEFNGIYLMTPFMNYEISAE
LCEYIQAKKQQEKSICSCGQVHSQ
>A0A2M8GWD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. HA2012|TrEMBL
MGYTHASHIDALNQNIAELSNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKEIKQQTGLIAAPHLTCIDATRDELKVIAEDYWQNGIRNIVALRGDI
PSGGGAPEMYASDLVELLKSLHDFDLSVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQASRFAAVNNVKVPGWMARQFDG
LDDDPVTRQMVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQK
>A0A5C7V799|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas sp|TrEMBL
MKSQQKFSPAFSFELFPPQTPQGIEKLRLTRKELAQFNPKFFSVTFGAGGSTRERTLETV
LEIQTEGYNVAPHLSCIGSTRQNIRAILDKYFQVGIRHIIALRGDLPSGMAQTGEFRYAS
ELVTFIRQEFGSVFHIDVAAYPEYHPQARSAQLDFENFKRKVEVGVNSAITQYFYNADAY
FHFIELCESSGLNIPVVPGIMPINKFSQLVRFSDACGAEIPRWIRKKLEGYNDDIASIQA
FGLDIVTDLCEKLLKAGAPGLHFYTLNSAHLTSIIWQRLDIHSDFN
>A0A2N8UJM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporisorium reilianum f. sp. reilianum|TrEMBL
MVNGTDSPLPPKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADL
GPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGC
RNILALRGDPPAGQSEWEPHAAGFTSAKQLVEYIRENYGDYFAIAVAGFPEGHPEAVDGP
EKELERLKEKIDAGADFIFTQMFYDFDIFAKWVKDVRAAGITCPIVPGVMPIQTYGGFQR
ATARFGTLVPQYFHDALDPVKDDDQKVRDVGTRLVGEMCKKIVGTGLGISGLHIYTMNLE
KGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRREEKIRPIFWANRAKSYVNRTETWDEFP
NGRWGDARSPAYGDVDAYGVKLRYSNEEAKEMWGAPTSLEDVKALFENFCAGHVKALPWS
ETPVARETSVISDKLTKMNQLGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEFF
VSPEDLDALIARIEADPQITYHAVNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVES
ISFLAWKDEAYEIGRNWAKVYEPSSPSRKFLEDMFNKYFLVNVVHNDFKAADSIFEPFLN
ASKATTAVNGSLSGLGATVSDAAGRVANSISSLTNGTSNGHASAPVPAA
>A0A4Q5L972|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter persicinus|TrEMBL
MKVTDHLSRAAGKTLFSFEVLPPRKGENIQTLFSNIEPLLEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGMFKPEPDGHSYACDLIGQVANLNKGEYLDEEQDDTWATNFCIGTAGY
PEKHFEAPNYGADLRYLKHKVDRGAEYIVTQMFFDNEQFFAFEKRCRDAGITVPIIPGLK
PLTTKGQLTMLPRSFYLNIPEELAEAVHLAPDNEAARQIGIEWCINQSRELMAHGVPCLH
YYSMGKSESIRRVAAALF
>A0A3D3EG27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
MRVIDLIKSPEKTAFSFEILPPLKGTGIEKLYETIDSLREFDPKYINITTHRSEYVYREL
GNGLYERKRIRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREDTEYVLLDLQFLGITDL
LILRGDKAKHEQVFTPEPGGYAHAIELEHQINDFNQGVFVDGSPIKAPVHPFSYGVACYP
EKHEEAPNMEQDIYWLKKKVEAGAEYAVTQLFYDNRKFFEFVDRVRQEGIDIPIIPGIKP
FSKLSQLSVVPKTFKVDLPQELALEALKCQTDEEARQLGVEWCINQCRELIAHGVPSIHF
YTVGATESVRRVAKEIY
>A0A5C7UML9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp|TrEMBL
MELSVEFFPSKTAEGATKLRAVREQLALALKPTFFSVTFGAGGSTQDGTFSAVKEIHEAG
QQAAPHLSCVGSSKEKISELLKQYKDLGIQRIVALRGDLPSGMGQYGEFHHADELVRFIR
SETDSHFHIEVAAYPEMHPQAKSMTDDVQRFAQKMKAGADSAITQYFFNSDAYFKFVDEA
AKLGVDQPIVPGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSFGDDSASIKAFGLEVVT
DLCDQLMVAGAPGLHFYSLNQAEPTLTIAKNLGLIKN
>A0A7W0KRY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MTRIADLLAKGTTWSFEFFPPKTPEGMVGFDAAVTGLSALEPSFVSVTYGALGATRDNTR
DLVIRVNEEQAFPAMPHLTCVGHTRAELMELLETYRARGVENILALAGDPPADGSDPGGD
FQFATELNELIHEVGDSSVGVAAFPEVHPRSPDRATDRRHLAAKLAEADFGVTTFFFDAE
DYRVLIDELADLGCETPVVPGVMPFVNVPGTRRMAAMNGSAIPDSLQARLDSVDGDAEGT
RRLGVQVASELVAQLLDIGVPGVHLYAMNRAQSIEEIYENLGLRT
>A0A8J8T4V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halteria grandinella|TrEMBL
MKIIDKINQVLQSEKDQDKTFYSFEYFPPRTEQGVENLLDRIERMGMTNPLWIDVTWNAG
GSTSDITLDLCSQIQTFSGLDVLMHITCTYMTRDKVLESLDRAKELGIRNLLALRGDPPR
GATDWIPIENGFNYAVDLVKFIREKYGDFFCIGVAGYPEVHLSAKSREDDIKYLKEKVDA
GADFIITQLFYDNNIFMKWFKDCREAGITCEIIPGILPILGYDRFQRTIQFCKTIVPPEV
SESLEPIKADDEEVRKYGIDFGVRQCRDFIDKGFRFLHFYTMNLERSVIEIIKGLGILDS
QRDLPFKKSSKRSKEDVRPIFWAIKPKSYIARTQEWDEFPNGRWGVSRSAAFGECEQYYL
LQKKINCNFEELKKLWGEQVLNFNDIITVFVKFLQGKIRRYPFSEGSLQPETDTIMDPLI
KLNQSKLFTINSQPKVNGAPSTDPKYGWGPKYGYVFQKAYYEFFIPQELLEPLVLYLEKH
PMITYQAINAAGVERLNVDKDDVNAVTWGVFKGKEVVQPTVVDHKAFVIWKDEIFLQWVD
PWAVIYPQESPSFAFLKRCHETLYLVNVVHNDFINGDLDQVLLGFVEENRALIDSL
>A0A7W0KT73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MTRISELLAAGPTWSFEFFPPKTPEGERTFDEAIADLVELEPSYISVTYGALGTTRDTTR
DLVVRLTAEQSFPAMPHLTCVGHTRAELVELLES
>A0A6L7K2L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MRNDSASLSRWEEPQPAGPNPDVQELIRNSAFEIIPLNSASEAIAALPPQSRVSITASAA
KGQAATLELAEELVNRGHHAIPHFSARLIRDRGQVKDLAEWAKYVGVTTAFVIGGDATEP
GPYHDAHTFMQDLFEHDHGLDTVGVAAYPDGHPLIGEDERRHALFAKQELLAEAGMRGYC
STQMCFDPARIIAWLKGERSDGLTLPVHLGIPGAVERAKLLTIGARLGVGQSLRYLHKNR
RSMAKLLGSSAHDPSELLEALSSQLTPLGINGLHIFTFNQVETTAAWQRALLHS
>A0A7C4FQ07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEFKTNSRLERVLKSGYFAVTGECGPPRGADPEAIRKKGELLKGCVDAVNVTDCQTAVV
RMSSLASCLILKEMGFDPILQMVTRDRNRIAIQSDILGAAALGINNLLCLTGDHQKAGDH
PQAKNVFDLDSIQMVAMVKRMRDEGKFLNGEDLTVRPRLFIGAAENPFADPFEIRHLRLA
KKVAAGADFIQTQCIFNIPKFKEWMKGVVDMGLHEKVFILAGITPLKSVGMARYMKNMVP
GMDVPDELIERLKGVPKEKQGEEGVKIAIEMIQEIREIPGVHGIHLMAIEWEEKVREIVE
GAGLLPRPQV
>A0A7V5M7R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSIDLETLLDTDQFLTFAQIEPPKGVDTTHFLKIADSLRSRVQGILVPELNGAIMRMSAI
GASALLKQRGFEPIVNFHGRDRNRLSLQADLLSAFSLGLKNIFISKGDEITSGDHIEAKP
VNDLDEISLLETIKKLQKGTDLIGNDLLGIPKFCVGAAVNAGLQRGALELEILDMEKKIK
AGANYFFTTSVYDLNALKNFMEKVSQFKVPIFPQIVILKSAGMARFMSRHIEGVVIPEKI
IDRLSKAPDKIKEGIAIATETIQELKSFCRGVLLVAIGEEERLSLVLDQI
>A0A800A6M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MLTHSDKWLRIAEINPPELPDMRHKALYPAWQHVLVTDNVFGRIRVSPFAFSARITHDTP
EVKPTVVVSTRDRNILAIESEVRGALMNGVRSFLVVIGDTVPHVDHLAHHYEIVEHLHAL
QEELPDFEVGMPTRFREWQFRRRIELGTQFFVAGPVLDPDVVEEQVDKLRLNGDDPPVFL
MVIPPFSPEWVDRMESIGSVPAGDKLRGRLDGLAPDVRRKMAWEITSEIEQRALDAGCAG
VVLMGLKFESVVSEAPEAWR
>A0A383S4Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium australiense|TrEMBL
MCVQHEYRPNAVAPQDRLDFCPDETIAQLLARADRPTISAEFFPPRDDEGQAILHRAIER
LEPLHPDFVSVTYGANGSSRERTLDAVRDILASTRLRVMGHLTCTGQSVDELRVVIDSYG
EMGVRHILAVRGDMPGGPLVPWQQHPQGLSNATELVELIKSRGEFCVGVGAFPDVHPGST
AENDVRVLCDKQAAGAEFAITQLFFRPAAYHRLVDRLRVAGCRMPIIAGKMPVTNIRQVD
KFAELSGAPLPDEMVTRLQAVAEDPEQVRSTGAQICAELARELLAGGAPGIQFFTQNRSA
ATRRILAMLESGAR
>A0A661Q6X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MDERASTLKGKLLEPNDFCITWEQIPGRGAFEIAHEEVLDNVAKAAAGGKVDAISVTDNP
GGNPALSTEMLCVQIKKAGMEPLVHLACRDKNRSEIESLLCGMAAEGIKNVLVLTGDYSG
SDAFEGLAKPVFDLDPPNVLRLVEKLNQGLEHQAGRKTIKLAATDLYAGACVSPFKKLES
ELMAQYAKLKKKIEAGAKFVIPQLGYDARKFHEILTWLKVNNYDVPVMMNIYVLPFGTGR
FMNGNGIPGCVVTDKQVAELAEEKKAADKGKSAMLLKAAKMYAIGKGMGMAGAHIAGHGI
TYEQVEFIIDKGEELATNWESLVAEFDYPQEDGFYLFEKDEKTGLNTEAYAERPAQPKPP
LMYKFTRLAHHLIFEEKSPVFKALKPVLGWVDKSKLPKHIMDYCEHIAKVSMFNCMNCGD
CALFDTAYVCPMSQCPKSQRNGPCGGSHEGWCEVYPNEKKCIWVQAYDRLKPYKEEDNIA
AYTVPPCNWQLWQTSSWLNFYMGRDHSAKRLGIKPPEPKETAKK
>A0A7L3MZJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oreotrochilus melanogaster|TrEMBL
MVNETQPTCSASSSSKSEGGSSSGSEGSKESSRCSTPVLDAERHERLRDRMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKEDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVGGFNYAVDL
VKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7V4UL89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGLEESLKSKRFVVTSEVQPPIGTGIQDLVRNIEKIRGRIDALTVPELKIEGLVTDTLGT
CRALKEQKFDPILQTTCREKSRVDIQEHLLKASESGIENILTFTEDYRITGDSLQEIMFF
HVDSGKLFSVIENLREGHDISGREIPGKPKFCIGAGIEAGWGKKVPDLELKEMEALAGMG
THYFLTTPVFDLDAFSQFIKRVQPLRVPVIAEIILVRSAEMGLFLNKHVRPGMVPNHIIE
KLAKAPDKEKASIEIIRDLVQGLKDLCQGVHFIPIGAEDRISKYLDALRL
>A0A7C5BCZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MREKMRGDGFLKLVEVLPPKSARGDVFEERLIPLKGLVDAIYIPQLPGAVMRAGSAFCAH
FLHVRGYEVIFEVNCAHSNRLAIQAELLGAGLLGLRNVVLSEGDEPKWGDHPEAKAVFDV
TLKELLQIVKAFREGKDLVGGDLEGALDLCVGVKVDASLQGEALKRELDRMEEMAHLGVE
FFLSSSVYDLEQLERFMEGASKIGVPVIAGLIVLKSAGMARYINKHVPGVMIPEGIIEKL
LRSPDKELASIEVAVEALKGIRRVCQGVNFITIGWEDKVPQILKEAEGLWQ
>A0A847SCB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leeia aquatica|TrEMBL
MSPSRTFSFEFFPPKTAEGMDKLRVTRRQLAQYQPHFFSVTYGAGGSTQEGTLRTVREIK
ADGYNVAPHLSCIGSTRDGIRGLLQGFQQEGIRHIVALRGDLPSGMAVAGEFRYANELVS
FIRECCGDHFHIEVAAYPEYHPQARSAQDDLNNFVRKVQAGANSAITQYFYNADAYFAFV
DAVQAQGVSIPIVPGIMPISNFSQLARFSDVCGAEIPRWLRLKLQGYGDDVASIRSFGLD
VVTELSDRLLAGGAPGLHFYTLNQAGLVSTVWQRLGL
>A0A7C4BJJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGLREAFESGKFVVTAEVGPLKGTDITEIKEVAHLLKGKVDGTNVTDQQSAVMRLGSMVT
CYLLKQEGLDPILQVTCRDRNRLAIQSDLLSAHVLGIRNVLAITGDYPTLGDHPDAKAVY
DIDSVQLVWMINRLNQGYDVAGNDLQGKTDFFIGAVVTPITDTEAALELQLIKMEKKIEA
GAKFFQTQAVYDIDAFARFMKRAEKFGVPVLAGIIPLKSVGMARYMNKNVAGVFVPEHLI
EEMQKAEKPAQKGLEIAARLIKEVKDLCQGVHIMAIGWEKKVPEILELAGLI
>A0A7C8A8H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSAKTPSRLEKILDSGHLAVTSECGPPRGSDPEAITKKAEMIKDHVDAINITDNQTSVTR
LSSLAACIHLKLMGIEPTLQMVVRDRNRIALQSDILGAASFDINNVLCLSGDHQMFGDSP
QGQNVFDLDSMQLIQTVRLMRDEGKFLGGDDIKRPPKMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNLDKFELWMKQVRDRGLHEKVYILAGVTPFKSAGMAKYMKNRVPG
MDVPDEVVKRMAGVPKEKQPQEGIDICIETIQRLKECEGVRGFHVMAIEWEEKVPEIVEQ
SGLYPRPEDL
>A0A7C5SSZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MFETFCDFLCNQTKQFITVEVNPPHGASLEGILADIKKHNLHEKVSGFSCTDNPLAKLKM
SGVLSAIKLQQTFNKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKLSDQP
EVKGVLERDSTLLLSIIYHLNNGVDYSNKPLNPAPKPIYPFAVSNAYAKDMKKLQKRMLK
KLNYGARAIITQPVYDTENAKELLALFEEAKEMSIRETAKEAQLVLGQFPIVRARTANFI
DDKVPGISVPKEIIDEMNLAAMDGEQKEQEVGFALSKAIFDDMMNLHGKVHLMTHNRFDL
CSALIG
>A0A1Q6YAP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ktedonobacter sp. 13_2_20CM_53_11|TrEMBL
MQHDFLEQLQQHPLLCDGAMGTLLYARGIAYERCFDELNLTRPALIQGIHSEYISAGAQI
IETNTFGANRAKLEAYNLEGRVRDINRHAVKLAREAREISGQSVFIAGAVGPSGRPLQAP
DEQRLSELRAIFREQIDALLVGGADLLILETFSSLAELRQAVLAAQDVGGLPIVAQMSFY
EDGHTLSGQSPARVAAVLNDLGIDVMGANCSVGPAATLDVLQEMIAAARLFLDNEQAIPQ
MFSAQPNAGLPTRIGNRFFYMATPDYFADYAVRFARAGVQLIGGCCGTTPHHIAAMRKAL
NDAYGAATPSIPGSSRETLQAKPVEITNGKVTIAGLIEEEVILPQQGTKTRLQEKLAARE
FVVSVELDPPKGLNPAKILEGAAMLQKVGVDFINIADSPMARVRMGCIALARLIQDHLGI
ETIIHFTTRDRNLMALQSELLGAHALGIRNILSLTGDPLHVGDYPNTTGVWDLDSVGLIQ
VLRRMNEGHDAAGSSIGAQASFHIGMALNLNMTEQETEQEIDKYRRKIEAGAHFIMTQPI
YELARLECFLARVGKPPIPMLLGCIPLHSSRHAEFLHNEVPGITIPDDVRSRMRAAGDQG
HEEGLKLAQELLTSARSMIQGVYLMPSYGRYDVVSKLTKMLQMQPTP
>A0A661HPM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MFDQFCQKLCSDDPFVTVEINPPHGASIDTIISKIKKSGVNEKVAGFSVTDNPLAKLKMS
GVLSAIKIQQTFDKAVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKFSDQPE
VKGVLERDSTLLLSIIYHLNNGVDYSNKALTPAPKPIYPFAVSNAYAKDMKRLQKRIIKK
LNYGARAIITQPVYDLENAKELLALFEEAKELSIRETAKDARIILGQFPIVRARTANFID
DKVPGISVPKSIIDEMNLAAMDGEEKEQEIGFALSKQIFDDVMSTHGKVHLMTHNRFDLC
NELIG
>A0A1H2A2B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium canariense|TrEMBL
MTENTPSAPNGHRPHDLPAISFEFFPPKTEEMERSLWETIKRLAPLAPNFVSVTYGAGGS
TRERTHSTIARILSETSLTPAAHLTCVDAPRANVDDVVAQYHAAGVRHIVALRGDPASGI
GGVYTPHPEGYSSSADLVASIKRRHSDIEVTVSAYPERHPESTDFDADIDMLKAKVDAGA
TRAITQFFFDNDLYFRYLDRVRARGIEIPIVPGILPVQNFKQAANFAKRAGASMPDWLAQ
KFEGLDDDPETRKLVAAAVAAGQVQKLAKHGVETFHFYTMNRADLVFAISHLLGIRPQAA
QKAA
>A0A1H0JZA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas shengliensis|TrEMBL
MSTQQHPLGISFEFFPPNTEAGREKLIGVRDALAERSPRFFSVTYGAGGSTQDRTLDTVR
RVRESGITTAPHLSCIGSEKGQLRELLARYREEGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFERDVENFARKVKAGANLAITQYFFNADAYF
HFVERARALGVEAPIVPGIMPITNYAKLARFSDACGAEIPRWIRKQLEAYGDDGDSIAAF
GEEVISRLCQRLLDGGAPGLHFYTLNQAAPSLRIVDNIVG
>A0A0Q7WLD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. Root552|TrEMBL
MTESFAPHHAHHLFDGYALEITGKDIAEISEARTAIAPATPINIAFLGNESHEQRINAAG
VIRACGFLPVPIISSRRLKSKEDRDALLSGLVRAADIDRIILVGGDPSSPAGPYRDSLDL
IESNILDDFGIRHVGIVGYPEGHPKIADTALWDALARKVELLRGAGRTVEITSQYGFDAE
AVIAWIEKVRALGIDAPIRIGVPGPANVKRLLRFAVQFGVGTSAAIVHRYGFSFASLLSK
VGPERFLAQLGKRLADDDLGVIRLHFYPFGGIAPTVEWIARQTEAHRSAALA
>A0A4R4U6D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora aridisoli|TrEMBL
MASELRRSLDRMRYEVLPVGNARVEALDPGSTVTVTASPAKGIGPTIDCAERLAAMGLHA
VPHLAARSIRDHAQLAGVLDRLDAAGVSEVFVIAGDAAKPLGEFVDSLALLRAMERMGRL
PARIGIAGYPERHAFIPDDCAVQAMSDKSHYADYVVSQITFDPRTIIDWARDLRNRGLEK
PVYVGVPGVVDAHRLLRIALKIGLGESTRFLRKQYGAVSKMLARYTPEELIDELSPQLGD
PGSPIAGWHLFTFSEVTKTVQWRDDLAARLSGYADRPA
>A0A520S5B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|OM182 bacterium|TrEMBL
MVNQHLSFEFSAPRNPVETKKLLSVYKRLKVFSPEFFSVTYGAGGSTKDGTKDAVLNIQK
LGSSVAPHLSFGGDTSEKIEALLQDYQKADIRRVVALRGDIPSGQMTKMTFASELITFIR
NKTGSHFHIDVAAYPETHPDSPSVESDIKFFKNKVDAGANSAITQYFYNADAYFRYIDKC
ASHNIDIPITPGIMPITNYNGIIRFSKNCGAEIPRWILKQLDSYKDNPDSLKAFGLEVVT
ELCSRLLEGGAPGLHFYTLNQSLPSARILRNLNAQ
>A0A3N5THM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
EFCIGTPIHLTTKDHDLEVRDMEEKMGLGVDFFLTSSIYDAGLFETFIKKTAHLKVPVIA
GVTLLKSAGMARYINKNVGGASIPETVIGKLMKASNKHEASVDIAKEMIRQLRPLCQGIQ
IIPIGWEPLIPVVLDQSGL
>A0A1N7NZR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleibacter marinus|TrEMBL
MTTLSFEFFPTKTEEGTEKLLKVRDELAAFNPEFFSVTYGAGGSTRDRTYAIVKAIQERG
IAAAPHLSCVGDSKDDLRSLLNEYKDLGIDRIVTLRGDLPSGAGLASSELRYANELVEFI
REETGDHFTLEVAAYPEMHPQATSFEQDLEHFVNKVKAGADSAITQYFFNADSYFNFVDR
VRDMGVDIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDNNESIQQFGEEVV
TEMCHRLLEGGAPGIHFYTLNQSEASLRVWRNLV
>A0A2E7ZM28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MQDFDKYIEQDFIQKIIQLSNRCMSDKIPNWSLEILPHHVSEVQGLPQWVEEIYVTMIPG
SKISEVVEASAQLVDEGRTPIPHIAARGMESREQFSEMLESLKQKGVNRLLLIGGGEEEQ
QGPFTEVMDLMETGELQRIGFEEIGIAGHPEGNPNDPDAENSLLKKTRWATKQGISTRIV
TQWCFESQTVNRWINNLREQGVTNPIHIGIPGPATLKTLLRYAQVCGVKASSEVLKKQGF
NLGKLLFVNKPDRLVQEIRGHQQLHLFPFGGLTKSSEWLQQQRNLASTA
>A0A252BMG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter sp. DsW_058|TrEMBL
MTISVGQVRADLMKESSIELLPSRILELSGVLPDLACGSRVFVTWLPGVPFADVLAACDL
LKLCGYLPVPHVAARSIRDEGHLQEICSALTERDIPRMLLIAGGADKPAGIFADTVQILE
TEIPVRTGIRTVYVAGHPEGHPQTSEATLLEYMRRKQELARTQGLNMQIVTQFCFDSAPV
LAWEKRLRDGGITLPINLGVYGLTTPKTLVRYGLACGVGQSLRFMQRQRWKLHRWFMPCN
PQHLVDAVAQEIAQTPDTNFRGLHFYPFGAIARTLEWRRALSLSTGDHS
>A0A661L2R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
VVDMGLHEKCKILAGVTPLKSVGMARYMAANVSGIIIPEEMIARLKGAGKGNVATEGIKI
LCEQMQELKETEGIAGIHLMAIEWEHRVPEIMEMAGFLPRPKP
>A0A352Z587|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNGHFAVTAECGPPKGADPDVIQKKGNILKGYVDSVNVTDNQTGVVRLCSLAACAILKRE
GLDPVLQMVTRDRNRIALQSDVLGASALGIRNILCLSGDHQSFGNQREAKGVFDIDSIQL
IQTVRSMRDEGKVIGGDVLIQPPDLFIGTTENPFADPFQYRVLRLEKKIMAGAEFIQTQC
IYNIARFKEWMKQVQDRGIDKKVYILGGITPMKSASMAQYMNTKVAGMDIPDHMIMRMKS
VAAKNQREEGIKIAIETIEVLKEIKGIQGIHIMAIEWEEIVPRLVEEAGLYPRPAV
>A0A2M8H8Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas lusitana|TrEMBL
MGFHSARQVEALNQSLADLGNNISVSFEFFPPNSEGMENTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKDRTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGVDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLSLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQTTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQL
>A0A109UYE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eremothecium sinecaudum|TrEMBL
MKIGQKLQEAGSRDNTFSFEFFVPKTEQGIQNLYDRMDRMYQAKPEFIDITWNAGGRLSK
QTTELVSTSQSALGLETCMHLTCTNMPCALIDEALDKAFECGCENILALRGDPPFQGGKW
QACEGGFRYAKDLVQHIRKRYGNHFCIGVAAYPEGDDETPDARALIPYLKEKVDAGADFI
ITQMFYDADNFLEWCRLVRGAGINIPIIPGIMPITSYTAFMRRANWCRVNIPREFLERLE
PVKENDQAVREIGTELVVNMCRKLLDSKYVTHLHIYTMNLEEAPLKILERLGLLQVDDSP
GSTSRQRSLSVESMPWRRSLNPQRRKESIRPIFWQRRPYTYVARTSQWSVDEFPNGRFGD
SSSPAYGALDLCDRPVLRHSYEKSLKLWSRPETIYDIANLIINYLKGNIDCLPWSDVPLN
HEVDSILDSLIRHNENLIFTINSQPKANGVPSNDPVFGWGPPDGYVFQKQYLEFLLPRHK
LDTLINLINTNYSILTFFSIDNEDNLNTNHPDDTKAIAVTWGVFPGREVLQPTIVEKVSF
IAWKEEFYRILDDWRLRFSANGDSKSAELLQTIINDYALVTIVDNNFISNDDMIGKLLSC
LY
>A0A2X2E3H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia rettgeri|TrEMBL
MEQTLWKSIDRLKNLKPQFVSVTYGANSGERDRTHSIIKDIKDKTGLIAAPHLTCIDASP
EELKAIARDYWNNGIRHIVALRGDLPDNSRKPDMYAVDLVELLKSEADFDISVAAYPEVH
PEAKSAQADLISLKKKIDAGANRAITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSN
FRQLERFAKLTNVRIPAWMSKMYEGLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYT
LNRSELTYAICHTLGVRP
>A0A534ZWK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKITDILARGGPCISFEFFPPRTPDGEATLLRTIEALKPLGPGFVSVTRTGAKPREAPVE
LVMRIRALGIEAAAHVTCIEASREELAAHYDLIAARAIDNVVAIRGDRPSDPGFRPPADG
FAYAADMIRFVRSRGHALCLIGGGHPEGHPECRDLRRNIEHLKMKVDAGLDAVITQLFYD
NADYFTFVERARRAGVGVPLIPGIMPITNVPQIERITALSGNQIPAALRAALERVRDDED
AALAIGVEWATRQCAELLRAGAQGIHFYTLNKSPATRAIFENLRSEGLVGAAPAHLATSA
PIR
>A0A2D6GJ51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEPADDLQENIEQNTTWSMEILPHNIAEVSLIPEFINEIYITMIPGATCLETIEAAQKIQ
AVGKQAVPHIAARSFTGAEDLEECLSGLEAAGIERALLIGGGHSELAGKISCVMDMLKTG
LFAKYGINAFDFAGHPEGNPDDPNSAVHMLEKLRWAEEQGASARIVTQWSLDTECTNAWI
SGLREKGVNNPIHLGIPGPSTLKTLMRFAKICGVKASTTVLRKQGLNLSKLMFVNKPDKI
IEELRGYDQLHLFPFGGIERSSAWLTEWQTKSYI
>A0A098FZ55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas xanthomarina|TrEMBL
MTALNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLTNFVRKARAGADSAITQYFFNADCY
FYFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQA
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A4S3KSG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metallibacterium scheffleri|TrEMBL
MQAPPATGARLPAPVSFEFYPPKTPEQHAQLERTVARLKAHAPQFVSVTFGAGGSTLSYT
PDTVRTLRATHGLDAVPHLSCMGGTRSEIAALLAQYREIGCTRVVALRGDLPSGMATSGD
FRYAADLVRFIRSEHARHFHITVAAYPETHPQAEDAHADVRHFAAKIEAGADTAITQYFF
NADAYFHFVEDARRAGVSAPVVPGIMPVSNFAQLRRFSEQCGAEIPRWIVRRLQAYGDDT
ASIRSFSADVVAGMCRRLIEGGAPELHFYTLNLAKPTEAVLERLR
>A0A1H0FUN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp. (strain JS666 / ATCC BAA-500)|TrEMBL
MNLPLSFEFFPPKTPEGAAKLRVARQALYAHKPEFCSVTFGAGGSTQEGTFGTVKEILDE
GVAAACHFSCVGATKATVRKQLAELRAMGVKRLVALRGDLPSGYGAGGEFHYASDLVAFI
REETGDAFHIEVAAYPEVHPQARSADADLQAFVKKVKAGADSAITQYFFNADAYFRFVDD
AQALGVDLPIVPGIMPIISSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVV
TGLCEQLYAAGVPGIHFYTMNQAAATTEIIGRLQRA
>A0A2E3NG91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MMWSTATDPVTSTDMSEAPIGNGGVRRGAVGGASRRSLAVGARGVNGHGVRCYAAPMGIS
EIYADASGPILSYEFFPPKTDASYRSLFKTIEDLKQLDPGFVSVTMGAGGTTREKTVDLT
IEITRDIGLVTMCHFPCTGYTPEQVGAILDQLESGAVRNVLALRGDPPKDDPDFVNPPEA
FDFANELVEFIAERGGFTIGGACSPEVHPDAPDLATDLVNLKRKVDAGCEFVISNLFLDN
QKFFDFEVAAREAGIDCPIIPGIMPIASVSGIRRMAGVNNTSFPAELEAELDRVDGDDEA
TYALGVRWATAQCRALIDHGVPGIHLFTLNRSPASREIHKNLFG
>A0A2D6GJ02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEPADDLQENIEQNTTWSMEILPHNIAEVSLIPEFINEIYITMIPGATCLEAIEAAQKIQ
AVGKQAVPHIAARSFTGAEDLEECLSGLEAAGIKRALLIGGGHSEPAGKISCVMDMLKTG
LFAKYGINAFDFAGHPEGNPDDPNSAVHMLEKLRWAEEQGASARIVTQWSLDTECTNAWI
SGLREKGVNNPIHLGIPGPSTLKTLMRFAKICGVKASTTVLRKQGLNLSKLMFVNKPDKI
IEELRGYDQLHLFPFGGIERSSAWLTEWQTKSYI
>A0A252BMK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter sp. DsW_058|TrEMBL
MPAQTGPLPAISFEFFPAKSEKAAATLLENAKTLAAFGPQFMSVTYGAGGSTRDRTLATL
KDMVRETGAPMAGHLTCVGASKEDVNAVAQAYWEAGVKHIVALRGDPPPSAGGVYEPHPE
GYAGAVDLVRGLKEIAPFEISVAAYPETHPAALSPQSDLEHLRAKIDAGADRALTQFFFE
ADTFLRFRDRAAAIGIERPIVPGILPVGSAAQAWKFADMCGANVPKWMRDLFDGLDEMPQ
ARAFVAATIADRLCQTLKAEGVEQFHFYTLNHADTASALCRLLGRRPI
>Q124L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp. (strain JS666 / ATCC BAA-500)|TrEMBL
MNLPISFEFFPPKTPEGADKLRVTRQALYAHKPEFCSVTFGAGGSTQEGTFGTVKEILDE
GVIAACHFSCIGATKITVRQQLATLQAMGVKYLVALRGDLPSGYGIGGEFHYASDLVAFI
REETGDAFHIEVAAYPEVHPQAKSADADLQAFATKVRAGANSSITQYFFNADAYFRFVDD
VRKLGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVV
TELCDQLCTAGVPGIHFYTMNQAAATTEILRRLQYRA
>A0A0Q7WEB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. Root552|TrEMBL
MSQFRFSRRPDIGDKIRVSFEFFPPKTDEMEARLWETVKRLEPLRPNFVSVTYGAGGSTR
ERTARTVARILGETSLSPAAHLTCIDASREEADNVIRQFAALGITRFVALRGDPAAGAGT
RYQPHPDGYANGAEMVGALKRHGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDIYERYVERVRRAGIYIPIVPGILPVHNIAQVASFSGRAGAHVPVWLRERFD
GLESDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLAFAVCHMIGIRSHKPEAS
PNSAAA
>A0A1F6LUK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lindowbacteria bacterium RIFCSPLOWO2_12_FULL_62_27|TrEMBL
MRISEMLARDGRTFSFEFFPPKTPEGEKNLYETIEVLREHHPSFVSVTYGAGGSTRAKTV
EIVSRIKNEIGIEAMAHLTCVGAARGEILSVLDKLKKERIENVLALRGDPPKGETGFTPH
ADGFRYASELVAAVREHDDFTIGVAGYPEGHVECESKEKDLENLKRKVDAGGEFIITQLF
FDPKDYFDFVARARAIGIRVPIIPGIMPVTNFAQIQKFTQMCGAHLPAEMRAALEPIQHD
PAQVQAFGVEYAVRQCQELLNRGAPGIHFYTLNKSPATRAIFSRLF
>U3U150|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plautia stali symbiont|TrEMBL
MSFFHTNQREALNQSLAELNGQINVSFEFFPPRTSEMEATLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRAIARDYWNNGIRHIVALRGD
LPPGGGKPDMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNAMFD
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPTLAA
>B7GRV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12)|TrEMBL
MHSPMFSLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGERLVGDFNHASDLV
SYIRSMKPDLTVFGACYPEGHYQSGSLDQDIENLKIKVDAGVTRLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLDALLNRWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFLGTQG
>A0A7K1ZN15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermaceae bacterium|TrEMBL
LAVGELARILDQSQPRLSHHLKSLTKAGLVERLPEGAWVFYRIQRRGWADRLLQGIFSKL
DVDSDPFTTDFNVLQRVRANRAQSAASYFSEIANDWDQLRALHYPDAAIEREILGHVECH
QFERIVDLGTGTGRMLILLAPYTQEAEGLDQSHRMLKVARANLNRAGIGNARVRQGDAMN
TPFESDSADLVIVHQVLHYLEQPERVIAEAARILKQGGQLIVVDFAPHELEFLRESQGHY
RLGISEDDMMRWADSAGFSMQPPRRFNPPSSLDKGLSVLIWKAAWRVYQPADPSVSKLSV
AEQQSKPPPNVSFEFFPPKSDSMEAKLWESVARLTPMAPRFVSVTYGAGGSTRDRTRRIV
TKIAQDTPLLPAAHLTCVSATKEEVLGIAVDLWKAGIRHIVALRGDPPEGIDAKFEQHPG
GFRDSIDLIEGIRNCEITPGARFEISVSCYPEQHPHSRGWDQDIAFLRAKQDAGADRAIT
QFFFEPEVYFKFLDRARAGGVTMPIVPGIMLQPNFKGMKRIADLCQVTLPNWLYEVFEGT
GDDAVTREFITANVAAELCHKLSDQGVNDFHFYTLNRASLALSTCRLLGLKPQAVA
>A0A6I7N8R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioalkalivibrio sp|TrEMBL
MNQPTNTDPVFSFEFFPPKNEEGAGRLRKARARLAALGPEYFSVTFGAGGSTRDRTLETV
LEIQREGSVDAAPHISCISSSRSELLDLLRAYRDHGVRRLVALRGDLPSGAGGGLGEFRY
AVELVRFIREEFGDHFRIEVAAYPEFHPQAANAEKDLEHFCQKVAAGADSAITQYFYNPD
AYAFFLERVSAMGVDIPIIPGIMPITNYTQLARFSDACGAEIPRFIRKRLEAYGDDTASI
RAFGTEVVTRLCQQLLDDGAPGLHFYSMNQAVPSEAVWKNLNLAPGR
>A0A7Z1LN95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSAGVGRMEPLAQTFVNAFSLEVSAKAMPALRAEAARIARGTTISIPYLPSEDDAARLAA
ARRVRELGFEPMPHLSARRIGSRAALEHFIEHAVIDAGIERCFVIAGDLATPAGPFADST
SIIESGILERAGIKVVGVGGHPQDHPVMTSAERWRVLENKCQRIEERGMAPLVITQFAFD
AGIVLAWLNELRARGITPPVLVGVPGPASIARLVRYATMCGVAASTSMLSRYGISIGRLL
GRAGPDVFVDRLAEGLTEAHGQVSPHLFPFGGIAPTMEWVEHYRMRAGDAHTTRSPVADE
PS
>A0A7M1T7Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoflavifilum sp|TrEMBL
MHVTEHIKRAQKTLISFEILPPLKGKSIESIYQHLDPLMEFKPAYINVTYHRSEFMFKKK
PDGSFEKVEIRKRPGTVGICAAIMNHYQVDAVPHLICGGFTREETENALIDLNFLGIDNV
LLLRGDPPKNEAYFEPEPGGHRYAVELIEQVVNMNHGIYLEEDLIDGVKTNFCIGVAGYP
EKHYEAPNLETDLCYLKQKIDKGAHYIVTQMFFDNQKYYDFVKRCREKGIDVPIIPGLKP
ITSRKQLSMLPRVFHVDIPQELASEVMKCKNDKEVEEVGKAWLVYQSRELIKFGVPVLHY
YTLGKPEVIKKALMEIL
>A0A1H4DDL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia sp. 21MFCrub1.1|TrEMBL
MSCTEARFSFELYPPRTDRAAASLPGTIDRLAAARPDFISVTYGAGGSSRTASLDVLRYI
LEHTDVSAMAHLTCVGSSHEEAHRLIREFLDAGVRRFLAVRGDPPEGLAEGEDGIGDIRT
TAELVQLIHRVQAERAPYGELAVPGLPAQAVLEHREHVQIAVAAFPNGHPSSHSVSQDID
ALLAKQAAGANLGITQLFFHAEDYFHFAQRAAEAGVTFPILPGIMPVTSPARLKRMLELS
GEDLPSDLAIELEVEPTDEGRREIGIAWAARLGERLIAGGAPGLHLYTFNQHEAVLSVLD
RIGALPATSGIASTTPANPATEKEPA
>A0A644ZRF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MKISDLIHQTSKPVFSFELLPPLKGNSIKQVFNTIDRLKEFGPKYINITTHHSENTYKED
ENGIIRKVNVRKRPGSVAIAAAIQNKYGIRAVPHIISQGFSKEETEYALIDLSFLGVTDL
LLLRGDTKKLDADQRKMDCHSYATGLQEQVNNFNNGIALDGSTFPAPETPFTYGMACYPE
KHEESPNMESEIYYTKMKAQNGADYLVTQMFFDNQKYFDFVDRCRAEGITIPIVPGIKPI
HLKNQLNVLPKIFRTEIPEDLEHELRKCKTDADAVEVGVEWCLLQSRELVQRGVPGIHFY
ALGATESIYRVAREVY
>A0A6B8JJG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAGTSSQADAFINAFSLEVSAKAMPALRAEAARIRRGTVISIPWLASEDDDARLAAART
VRELGFAPMPHLSARRIGSHAALERFLERATSEAGITRCLLVAGDLATPAGPFADSASII
QTGLLEHSGIKVVGIGGHPEGHPVMSADDRWEVLGRKCQAIEARGMAPLVVTQFAFDADT
VLAWLEALRARGITVPVLVGVPGPASITRLLRYATMCGVGASASVLARYGISIGRLLGTA
GPEVFMDRLLSGLTDAHGPVSPHLFPFGGIAPSLEWVEQYRRSIYSSGG
>A0A6C1NNA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MTPPAGTAPGQGPDGLRQRLTGGGIHLMDGAMGTVLYDRGVFVNVCYDELNLTRPELVED
VHRQYAEAGARILETNTFGANPVKLSSHGLEARTAEINRAAVDRVRGGIARARLPAGTPP
ESLHVVGAMGPLGIRIEPWGPTAEAEARSFFARQVEGLLEGGVDGFVLETFSDLRELEQA
LRAVRELSTLPVVAQVTIESDGRTSYGTGVAEAARRLEALGADAVGLNCSVGPAEVLDAV
EIMVGATSLPVSALPNAGLPRSVGDRKIYMASPEYMARYARRMAQAGARLLGGCCGTTPE
HIRQMAGAVASLEVDRGANASRSNEAHDVSGAPGPVVPSSPLSRRVEPSPLADRSPLGRR
LSEGTFLSSIELVPPSGWDPAPLLAAARRARLAGVDVVAIPDAPRGRARMASLPAATLVE
RETGLDVVAHYACRDRNMVGMISDLLAAASTGIRNVLVVTGDRSPAGPYPDHTALLDIDS
IGLVNVLHHLNHGVDPGGHPVEPPTPFVIGVALGQHAPDLERELRRFRWKVAAGAEFAVT
QPVFEAEAVHRILDRAFAADGPAEGAPPIRPIPVMAGLWPVASVRTAEFLHHELPGVHVP
DSVMERMGRAEAEGPERAREEGISIAVEAARALRGRIAGIHVSCSAGEVEMALEVVRRLR
QAPGAASASEAASEAAS
>A0A8I0Y2L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAARLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
AKLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A8E3RMH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAGLSLRADAFINAFSLEVSAKAMPALRAEEDRIPRGTVISIPYLASEDDDARLAAART
VRALGFEPMPHLSARRIGSAAALARFLERAVGEAGVARCLLIAGDLATPAGPFADSASII
QTGLLEHSGIKVVGIGGHPEGHPVMSSDERWQALERKCQAIEARGMAPLVVTQFAFDADT
VLAWLDGLRARGISVPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGISIGRLIGTA
GPEVFVDRLVRGLTSAHGQVSPHFFPFGGIAPSLEWMVQYRRRISGTGG
>A0A1H0YKB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus equinus|TrEMBL
MSGLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPEKVLAIHKAYIEAGADVIQT
NTYAAKRHRLEGYGYGNKVKEINQAGVKIARQAAGEDTFVLGTVGALRGLKQCELSLDEI
IKETLEQVGYLLETKEIDGLLFETYYDEEEIVEVLKAVRPLTDLPIITNISIHEAGITEN
GRPLVEIFGKLVMLGADIVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAIKGLKPVSRKFVTP
MVEEAELIKAVKQSETIVDKVKRKVTIIAELDPPKTLDIRKFTEGVKTLDEAGVSAITLA
DNSLAKTRICNVSIASLLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIKQLNKGIGYSGASIKKETTFTAAAAFNPNVKNLS
RCGRLIERKIAAGADCFITQPIFNSEIIENLAELTRDYETPFFVGIMPITSYNNAIFLHN
EVPGIQLSDDFLAKLEAVKDDKEKCQQLALEESKQLIDHALKFFNGIYLITPFTRYDLTV
DLVEYIHQKVEQSHQIIP
>A0A645BSS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MKIIDLINSNEKTAFSFEILPPLKGTGIEKLYTTIDTLKEFDPKYINITTHRSEYVYKDL
GEGLYKRDRQRRRPGTVAVAAAIQNKYNIKTVPHILCSGFTREETEYVLIDLQFLGVTDL
LVLRGDKAKHESVFTPEGDGYYHAIQLQEQINNFNKGIFVDGTSMQNMEQPFSYGVACYP
EKHEESPNIEDDIYWLKKKVEAGAEYAVTQLFYDNKKYFDFVDRARQAGITVPIIPGIKP
FKKLSQLTMIPKTFKVDLPEDLTKEILKCKNDNEAQQVGIEWCIAQCKELIEYGVPSLHF
YTISAVDSIREVAQKIY
>A0A3R8VFL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MAAPTSLRARAFLDAFSLEVSAKAMPALHAEAARIPRGTTISIPWLASEDDDARLAAARR
VRELGFEPMPHLSARRIGSRVVLERFLQRAANEAGVAQCLLIGGDLATPAGPFADSASII
ETGLLERAGIKAVAIGGHPEGHPVMGSVGCWQVLEHKCQAIEARGMAPMIITQFAFDADI
VLAWLVALRARGIDVPVLVGVPGPASITRLARYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDHLVSGLTDAHGLVSPHFFPFGGIAQSLDWIKRHRPQASAVGG
>M3ERD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Lora str. TE 1992|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A2J0SQX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYDPQYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIAFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLRG
>A0A1V1STW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|fungal sp. No.14919|TrEMBL
MHINDMVADAERTGEPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFVDITWGAGGRIA
ELTCDMVLQAQTFFGLETCMHLTCTDMGEEKVNDALQRAYKAGCTNILALRGDPPREKEK
WEATDGGFQYARDLVAHIRQKYGNHFSIGVAGYPEGCDDNKDEESLLDHLKEKVDMGGTF
IVTQMFYDADNFVRWVGKVRERGITVPIIPGIMPIATYASFLRRAHHMNCKIPEKWMAAL
EPIKNDDSAVREVGKVLVAELCRQIMSAGIVHLHFYTMNLAQATRMVLEELDWLPSSQRP
RQQPLPWKQSLGFGRREEDVRPIFWRNRNKSYISRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNESNRKKWGEPKSISDIASLFARYLEKDLDSLPWSEAPLSGEAVSIKDDLIN
LNKRGFITINSQPAIDGVKSTHPIYGWGPPNGFVYQKAYLELFVHPELYDEVIRRIERRE
TLSYYAVNLAGTFTTNAPSEGPNAVTWGVFPGKEIVQPTIVESVSFLAWKDEAYRLGNDW
ARCHEANSPSRALIEGIMNQWYLINIVNNDFHDTKAVFELFDGLEVKDLETPVFSAPHTN
GTNGTHKETSSIAAPN
>A0A644UQP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MKVIDLIQGSGKTAFSFEILPPLKGNSIQKVYNVIDKLREFDPKYINITSHHSEYIYKTL
PDGKMEKVNIRKRPGSVAIASAIQNKYNITAVPHIICKGFTKEETEYALIDLNFLGVYDL
LLLRGDIKTLEAADANSKLYHNHATDLQEQINNFNKGIAVDGSTFEANETPFSYGMACYP
EKHEEAPNMDSDIHYLKQKVANGADYLVTQMFFDNQKYYDFVERCRAEGIQVPIIPGIKP
VVFKNQLTVLPKIFRSDIPEPFASELRKCNTDEEAREVGVEWCINQCKDLVAHGVPSLHF
YTMMATDSVYRVAKEIY
>A0A520S2A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoricolaceae bacterium|TrEMBL
MTAPRVSFEFFPPKTPEAEAGLWKTVERLAPLNPEFVSVTCGADGSTRERTHQVIESILT
KTSLKPVPHLTCVGAPRSEIDSIADGYWDMGVRQIVALRGDPEGGAEAAYVPHPDGYAFA
PDLVQGLLERHPFELFVAAYPETHPQAGSVDADLENLQRKVDAGGHRAITQFFFDNEIFL
RFRDRVAAMQIDVELIPGILPVTNFNTLVRFAGACGASVPTALSMQFEGLDDDPTTRQLI
AAHAAVSQAEDLGREGVEDFHFYTLNRADLSFAVCHALGVRGCA
>A0A0G9HCZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter rhizovicinus DSM 16549|TrEMBL
MPAISFEFFPPKTDEQRAQLDATVGRLKKHAPDYVSVTFGAGGSTLSYTDETVKRLRADH
GLSVAPHLSCMGGTRAEIAALLDLYKATECRRIVALRGDLPSGMASPGDFRYAAELVSFI
REHSGNHFHIEVAAYPETHPQAENALVDLRHFKAKVDAGADGAITQYFFNPDAYFRFVDD
VTRLGVNIPIVPGIMPIANFSQLRRFSEQCGAEIPRWIVKRMQAHGDDAAAVRDLGAEVV
AELCQRLLDGGAPGLHFYTINRAKATINVLERLAAR
>A0A1F5VMU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Fischerbacteria bacterium RBG_13_37_8|TrEMBL
AKHLALEKEVPVTAYLAGICLTESQVKNILDNYHAIGVQSVLCVRGDNPHDGAPAEDTGD
FQHATELLTFVKSNFGFQLGAAGYPEGHVEAESKETDWDYLKLKVDKGAQYIISQYFYDN
DYYYEFAENCRKRNINVPIVAGVMPIYSVKMMENLAAMCGATITQRVREGLAQINVEDKE
AVGAFGIELALQQCRELLRNDVDGLHFYTMDRSQSVAKIVQQLRKEGVVP
>A0A3S2G0B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.06.1.1|TrEMBL
MNDMRQELIQTRGSATFAFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLATAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLEICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWLRVNER
>A0A0N1H7A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium OV320|TrEMBL
MALGTASTRTDRARTVRDILATGKKTYSFEFYAPKTPKGERSLWNALRRVEAVAPDFVSV
TYGAGGSTRATTVKETQQIVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDTDVTHFVD
KCRAGADYAITQMFFEPESYLRLRDRVEAAGCVTPVIPEVLPVTSVKMLESLPRLSNAHF
PAALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>F0W2Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Albugo laibachii Nc14|TrEMBL
MRAIDKITDCISKKQVFFSFEFFPPKTAAGVQNLYKRIDRLGQLGPLFCDVTWGAGGSNH
GSTIEISSNAQKMGMDILMHLTCVNLTPENAITALDAARNAGIQNILVLRGDPVQGASSF
EECDKGFSHAIDLIRFIRKKYKDAFCIGVAAHPEGHLHAADKQQELVYLKEKVDAGAGFI
ITQLFYDVFVYKEFVCECRQIGITCPIIPGVMPIQTYGGFVRMTSFCEARVPGEIQDALE
PIKGNDEAVKEYGIRLGVKMCRKLLEDGAPGLHFYTLNLERAVRAILSELNLVNVNSIRE
LPWHSTCCIKRAGESIRPIYWSNRPESYVARTALWDEYPNGRWGNSESPAFGELSDSPYV
TTKLSASERREMWGHALKSTNDITKTFVSYVRGDIKSLPWCNTPLHLETKSIREQLISIN
KSGYWTLNSQPKVNGAPSEDPVFGWGGDYGHVYQKAYIECFTSPQQLRKLMDRASAMNSI
QYYAIDSKGNSYSSAGNSVIAVTWGVFRDKEILQPTIMDRASFIAWKDEAFALWISMWGI
LYEKDSESQRLIREIHDSYFLVSIVENDFVHGDIWALFHDEIKELENGN
>A0A4T9TBB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvibacter caecicola|TrEMBL
MFPPKGQLTLDAARTVAAGLAQARPSFVSVTCSAGGSGNSAQTVDIAALLQNEFAIPGIA
HLTCVGATRASLDQQVRRMREAGITTVLALRGDMAEGQEPGDFLYAKDIIPLLKQEGFTV
GAAAYPEGHISCFSAADNLWHLKEKQEAGADFFVTQLCFDNDVLLRFCRQAKEAGVTAPI
TCGIMPFLAKSQLQRMVFLCGSSLPAPIIKLLAKHEDSPEELRQAGIRYACQQLVGLAQA
GVDGLHVYAMNQPDIALAAAEALAAEGLR
>A0A644W3S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MTVIEKIKSSKSPLFTFELLPPLKGHSIEKVYATIETLLDFNPAYINFTSHRNEVQYFEH
PDGTLEKRTSRLRPGTIALAAAVKYKYNITVVPHLLCGGFTREETENALIEMSFLGIEDV
FALRGDPPKGSRSFIPEKGGNNYASDLVKQINEMAGSRFCTGVAGYPEKHFEAPNLEIDM
ENLKKKVDEGAHYIATQMFFDNSAFFRFRDNCRKAGIEVPIIAGIKPISAMNDIKLLPQT
FHIDIPADLYNAVNKCNSDEEAREVGIEWTTMQSRELIKEGVPGIHYYTLGRADNIARIV
KASF
>A0A542I407|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. SLBN-83|TrEMBL
MATRTMPVPNRVASLELIKDFSLEMTGKDIPALIEAKDHIPPRTRINVTFLGNEDLEMRV
AAAKAARDLGFVPVPHISARRLASKGDLEKFLQRLAEVGAAEHLFLIGGDPAEPEGPYGD
SLALVNTGLLQQFGVREVGIGGYPEGHPDIPKETLWQALEDKTAAIAGENLDAFIITQFA
FDTGPVAGWIEEVRARGINAPIRVGTPGPAGVKRLLGFARRFGVGANAMIVKKYGFSLTN
LMGDAGPDRFVNDLAAVLAQRAPGQDQHLPPQLGLHFYTFGGLLATANWVRHFTAEER
>E8LFR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phascolarctobacterium succinatutens YIT 12067|TrEMBL
MTSEKIIDILKNGKIHLSCELFPPKQGAELQNSLEIVNKIAASTPSYMSVTYGAGGSTVG
YSAALAKKVEDNGMPALAHLTCVKADEAKLAEVLGQLQGFGVKNILALRGDIPADMQGEE
IGSFAHASELMRFVKQQGDFCVGGAAYPEGHPESGSLEKDIENTKYKVDAGVDFLVTQMF
FDNTILYNYMFRLLRAGINVPVVPGIMPVTNAKQIIRICQLSGTKLPPQFRAMVEKFADK
PEALKQAGIAYATGQIIDLIANGFDNVHIYTMNKPEIFAGIMNNLGEIVDK
>A0A8J3WHA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planobispora rosea|TrEMBL
MTDRPFEVVCEIEPPTRPDLKHVRHQIGTLSKIAGSFLIPDNHIGRATVSSVAVAHEVQA
MGGRSIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTTGNRTSDLTVRSMIEEV
RSLGEDPGFAGVPAFRVGTAAGLRPLPAWKRTADFVFAQVSFSLETLLRWREANPVDVPV
YAGVMVIASENHARRLAAAIPDIDIPAELVERVAGDRLAGVEAACEHVLRVRDSGAFDGV
HLIPVARYREVESRLVGVL
>A0A7W6IL61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia subaequoris|TrEMBL
MIDDNLRASRKTADQRPDLQLSFEFFPPKTDAMEQRFWDSIAKLAPLSPRFVSVTYGAGG
STRERTLRMVRRITTDTGVPAAAHLTCVGATRDEVDEVVRGYAEAGVNKIVALRGDPPEG
VGQPFTPHPEGYQNAADLVAGIRRLGNFDISVAAYPEKHPQSADWDADIDNLKRKIDAGA
DRAITQMFFSNTDFLRYLDRARKAGITAPIVPGIQPIHSFKQISGFATRCGASIPDWLAE
RFEGLEDDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRT
>A0A6I7YQ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. LK14|TrEMBL
MTPRLSASAPLDQFSEVSVKPRQRTALSFEVIPPRNDADASTTAELLKVLQGYNPDYIAV
TSSQRSGWLEGTAAFIEQISRTTSMRPLAHLACTAGTREELIGWIDALVDAGVRGLLALR
GDLPEGGMPAHYLQHADELVRLIRHREAGQAARFAAGSLAVGVACYPNGHAESANLDEDF
DVLLAKQRLGADFAITQLFFDAEDYARFAQRARLAGVRIPLIPGIMPMTSVARLERMAKL
SGLQVPPRVRAALAAASTPDEEHEIGMELTAELTRSVLRSGADGLHIYTHNNPHITQDLL
NRIGVHP
>A0A7C6Q0E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MTNEFRQIINEPNGFVVTWELVPGRGATEESQEKVLQLASQAAKGKKVTAVSLTDNPGGN
TGIVPEVIGKEIAYLGLDTIIHLTCKDKNRNQLESQLYALERLGLTNILAMTGDFSRGGI
FGRPKPVFDIDSTHLLNMITEFNKGLRIPKQKKETVLKPASFFAGAAVSPFKATEAEQIL
QYSKLRKKIASGAQFVITQVGYDARKFHELLLVLENMNCKIPAIGNIYVINYPVGRIMNS
NQIPGCVVTDKFLARLAEERESADQGRAAMIERAAKQYAILKGMGYKGVHLGGANLQYEQ
VEYIITKGEELSANWRDYIREFDYEQENGFYLFEKDPQTGLNLNHYKEKVSGSKAGLDFN
YTLSRLFHKMFFEPNKNFFGPMKSLVQRIEGKGPEKLFHCLEHGAKALLYNCQDCGDCAL
IDTAYVCPMGNCPKNQRNGPCEGSYNGWCEVYPGQKQCIWVPAYNRLKKFGEEDELNSYQ
VSPYNWELQHTSSWINFYLGKDHSAERLALKTKEDDSK
>A0A510HK93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacter xylanophilus|TrEMBL
MGDGLKGSGKGISALLRRLRYEIIPLEGIEEGVWEWVYEGERSPTLTITASPARGMGPTV
ELVRRLREGGYAGRALVPHLSARLIRDERHLEEIVARLKEAEVEEVFVVGGDAKEPAGKF
RDALGLLEALKELGSPFERVGIAGYPEGHPFIEEKALMEALIEKSAHASYVVSQVCFDAG
RVVKWVRKIRGLGVRLPVVVGVAAPIEAMRLARIATRIGVGESARFLRKQRGWLLRLLLP
GKKAGLSYDASGFLEALVREGGGEGVSGIHLYTFNDLKSSVGWVRQEKGKG
>A0A7K9GA12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loxia leucoptera|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDHMGAGGPLFVDVTWHPAGDPGSDKETSSMIIAYTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVHGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVYAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVRALLKVLKKYELRVNY
HIVNVKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A4U0YHV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Guyparkeria sp. SB14A|TrEMBL
MSIPVSCEFFPPKSDEGEAKLREVYQTLARDIRPEYFSVTFGAGGSTQTRTFETVREIQR
DSGVPAAPHLSCIGSSREGIAAILDDYREQDIRRIVALRGDLPSGMQDPGDFRYANELVA
FIREHSGDWFHVEVAAYPEIHPQAPNAEADLANFKRKVDAGADAAITQYFYSIEAYRRFL
DDCERLNIDVPIVPGVMPITNYQQLARFSDMCGADIPRWLRKRLEGFGDDLEGLRAFGHD
VVTDLCRELVDAGAPGIHFYAMNRSGPVIRLCEDAGLIGD
>A0A832NH53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorella mulderi|TrEMBL
MKTESKLKRLLDSGHFVVCGEIGPPKHACPERLVEKTLMLKDFVDAINLTDNHKAVVRLS
SIAAAVHVLRAGSEPIIQMTVRDRNIIGLQSDLLGAYSLGIKNLLCLTGDHPSVGNHPTA
TMVKDVDVVGLIRIAKKMRDEKRFACGEEIKGQEPRFFIGAVTNPFMGSLNQEVERLEKK
VEAGAQFIQTQCVFDKEYFDLFMDLVRERQIHKRAYIIAGVMPLKSAKSARYLQTSVPGM
RVPEEVVLRMERTSYPEEEGISLSIEMIEHLKKVEGIAGIHIMTVMWEEIIPTIVREAGL
FPRPKVKEVLLGSQDAYTEGRKSCQEVG
>A0A7Y1ZPY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermales bacterium|TrEMBL
MKIIELLENRRESLISYEIIPPVRGGSVGDILRLVETVMKYQPPFIDVTSHSAEVLYEEL
PDGTWRRKVKRKRPGTIGLCAAIKGRFGVEAVPHLLCEGFTREETEDALIELNYLGLQNL
MALRGDKGGFSKPLPASKSRNRRATELVEQIVDMNEGRFLEELIDAVPTDFCIGVAGYPE
KHFEAPNMARDLQNLKEKVDAGADYITTQMFFDNQHYFSFVEKCRAAGIDVPILAGLKLL
TSKSQLKSLPSRFYIDIPEALTAEVEAADPKHVTDIGVEWAIKQSEELLNAGVPCLHFYI
MQTAAHVERVVSSLRKMA
>A0A3S0JXY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas nitroreducens|TrEMBL
MIVGADHGNLASDTLGYSSAGRLERVLRSGHFAVTAELAPPDAANPEEVYARARVFDGYV
DSMNATDGSGANCHMSSVAMCALLSRMGYETVMQISCRDRNRIAIQGDVLGGAALGINNI
LCLTGDGVQVGDHPEAKPVFDLDSMSLLETVARLRDKHVFASGRKLSDPPRVFLGAAENP
FVPPYDFRPHRLAKKIAAGAQFIQTQYCFDLPRFRTFMARSRDLGLLDKCFILPGVGPLA
SARTADWMRRNVPGIHIPDDIIKRLEGAKDQKAEGRNICIELIQQLREIEGVSGVHVMAH
RQESSVADIIERSGVLGDREPWPPFSEPTLERDYA
>A0A4Q7K1U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pochonia chlamydosporia 123|TrEMBL
MHIKQMLVDAEKDGQPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGMEKVNDALQRAYKAGCTNILALRGDPPRAQEK
WTATEGGFQYARDLVKHIRATYGDHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGKVRERGITIPILPGIMPIATYASFLRRAKHMQCKVPDEWMTAL
EPVKNDDVAVREIGKTLVAEMCRKLLANGIHHLHFYTMNLAQATRMVLEELTWAPCAERP
LQHALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPQTVQEIAQIFVKYLNQEIESLPWSEAPLTGEADAIKDNLIE
LNKRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPASIFTEMVKRIEDRP
TLTYYAVTKDGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGTDW
AHCFDSDTPSRVLLDQIMNEWYLVNVVNNDFHENQAVFDLFEGLEVKGLDTPVIV
>A0A1H6EI27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora kobensis|TrEMBL
MTKVIDRLRPGKTVFSVEFFPPKTDEEERQLWRAIRELEPLDPAYVSVTYGAGGSSRDRT
VRTTGRIARDTTLVPVAHLTGVNHSIAELRHVIGSYAAEGITNVLAIRGDPPGDPLGEWI
PHPEGITYADELVRLVRECGDFSVGVAAFPHMHPRSPDLESDTEHMVNKLRAGADFSVAQ
MFLEPEYFLRLRDRLEQRGCHQPLLPGVMPITTPKVLGMTTQLSNMTIPDEVSAVLDPLR
EDAPGFREAGLEITTRLCEKLIAEGVPALHFYSLNRAKATREVLANLGLIDGVLKAA
>A0A552A4T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa Ma_AC_P_19900807_S299|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A444J8L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electrothrix communis|TrEMBL
LKKCGYQGVHLGGANLQFKDIAYVLDRVEQLDREGIPDNAGYDFPVPGTWYYFQHPLPGD
KGNMTTEPLALGTVLGTTWMHKLGHTLLFTNQYVTGKLFARFCLFCARERRRLNILLWLE
KTIKRQVYNCQMCGECTLSHSAFLCPQWHCPKRLINGPCGGSNQGRCEVHPERLCFWVRV
YNRLDNQTSLASLADTPHLSPKDWQREKTSSWVNFFSDQQKEEN
>A0A1W9HIM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium SG_bin6|TrEMBL
MTMSFHDLEEARRALDAPLFADLAGDAQVSFEFFPPKSEKMEGQLWEAIKTLEPLGPRFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATKAEIAEIADAYWAAGVRHIVA
LRGDPPVAGASFAPHPEGYASAADLVAGLKKLHPFEISVAAYPECHPEAVSAASDIDNLK
RKIDAGATRAISQFFFTPECFFRFRDAAAAAGIEAEIVPGILPVSNVAQTRKFAAMCGAE
IPAWMDRLFEGLDDHPPARQLVAATIAAELCRRLYAGGVRHFHFYTLNRAELSFAICHLL
GLRAGTAAAKAAA
>A0A173ZGE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudocatenulatum|TrEMBL
MHSPMFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVS
EYGIPSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFEHASDLAV
YIRQQRPDMKIYGACYPEKHPQSATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KARAVGIDVPIEAGIMPVMNAKSVLNMSNKCQSKVPEKLGIMLDKWGGDKALLKEAGIAY
ASEQICELVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A1H6DN94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora kobensis|TrEMBL
MTVVDRLGTGRTTFSVEFFPPRNDEEERVLWRAVRELEPLDPAFVSVTYGAGGSSRDRTI
RTTGRIAQETTLTPMAHLTAVDHSVAELRNVIGWYAASGVRNVLAVRGDPPGDPNGEWIS
HPEGLEYAEELVRLVRDLGDFCVGVAAFPHGHPRSADLDTDADHLVRKIRAGAGFAIAQL
FLDPEYFLRLRDRLAARGCDAPLLPGVMPITTPRVLAKFGELAGVPVPAAISDRLLPLAD
DPAAFRQAGVEVVTRLCERLIAEGVPALHFYTLNRSKATCQVVSDLGL
>A0A1X1CUJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea rwandensis|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSILKPKFLSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRGIARDYWENGIRHIVALRGD
LPPGSGKPEMYGADLVELLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNTMFE
GLDNDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPPASA
>L0GHY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri RCH2|TrEMBL
MLASRSDLQRLEDVLGAPRPTTLDSPMSTSPRPSISFEFFPTKTDAGHEKLLNVARQLAG
YQPDFFSCTYGAGGSTRDRTLNTVLQLDGEVKVPTAPHLSCVGDTKAELRELLNIYKDAG
IQRIVALRGDLPSGMGMASGELRYANELVEFIRSETGDHFHIEVAAYPEMHPQARNFEDD
LANFVRKAKAGANSAITQYFFNADCYFYFVERVRKLGVDTPIVPGIMPITNYSKLARFSD
ACGAEIPRWVRKQLEAYGDDMQSIQAFGEQVITEMCQKLLAGDAPGLHFYTLNQAEPSLA
IWNNLGLSR
>A0A849K203|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Isoptericola sediminis|TrEMBL
MAAPDPPRPWLLFAITPPRRSTEPAEAQRIADRTCARLRGLDLDALVIYDIDDESDRTSA
ERPFPYLPTLDPGDFHARHLQAWDRPVIVYRSAGKHDPAALGDWFAAQDPQRVRTVLVGA
SSSDAAVRTTLSQAQRLRREHAPDLPLGGVAIPERHASRGDEHERMRAKQAAGVSFFVTQ
VVYDVGAAKSMVSDYHYACGDAGQPTVPVVFTLSVCGSARTLAFLEWLGVHVPGWMRNDL
RHTDDPLGTSYDQCVAIAEDLAQFCTRHRIPYGFNVESVSIRRAEIEASVRLAAHLRARL
DADARGRVGGDGTDRPVQAAAASASSTPGQPRS
>A0A6G2IKP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HUCO-GS316|TrEMBL
MALGTASTRTDRARTVRDMLAAGTTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVRATEQIAADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPRGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDTDVTHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCVTPVIPEVMPVTSVKMLERLPQLSNAMI
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A1I7YF70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steinernema glaseri|TrEMBL
MGLNPAYVSMTFGAGGSTRAGTVDAVALLQKLGFDVAPHLSCIGTAPAQLKEMLDNYRDQ
GIRRIVALRGDLPSGMGGDAGELRYASDLVAFIRENYGEQFHIEVAAYPEMHPQATGFGD
DLGHFVNKVNAGAHGAITQYFFNPDSYFSFVERAQAQGVTIPITPGIMPITNSSQLLRFS
TMCGAEVPRWIRLRLADFGDDRASIRAFGIDVVARLCQDLLDGGAPGIHMYTLNGADASM
AILPNLTWR
>A0A1W2GG08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. JKS001846|TrEMBL
MKLLDLLSKGVVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0F8CIS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. 2.H.T.1A.15|TrEMBL
MLFNFREKLNSRKFLVTVEVSPPKGTMFSAPLEDACQLKGVADALNVTDNQCSIMHMSSL
AFSKLLLDQGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDHPACGDHPGSKP
VYDLDSVQLIELVRKLDSGIDFAGKRLDGGTSFCAGAVSGIDPENTLQLIKLEKKVRCGA
DFIQTQAVYDVGMFEEFMEAVNHLEVPVIAGLIPLKSLSMAEYMNKNISGIHVPEEIRLR
MKDASSPIEEGLSIASDTIKELTKLSRGVHIMPIGSHKNTPRLLSMAGISGK
>Q8Z302|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhi|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVVDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0X8D263|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aneurinibacillus sp. XH2|TrEMBL
MTMPKESLKTYLKDHLLIGDGAMATWLYQLGIPIGVCYEELNLSNPELIRAVHRSYYEAG
ARFIQTNTYGAHRDALARHGLQDKVTRINRVAVQVAREAVKDDAYVVGGIGSINAGRVRD
VRMQNYREQFEEQAAALLMGGVDAILLETFLDLDELLLALDVIRPLTDVPIVAQLATIEV
GRTRDGHTLTRAFAELKKAGADVVGLNCRLGPAEILRSIENAVVPEDTPLSVFPNAGRLA
MSDGQYSYASVPQYFGENALRFRAQGARLIGGCCGTTPEHIRVMAQVLAEREPLPRVNPV
VDTQEEAEPLIRIDPPARKQGIVETVAHRHTVIVELDPPRDLDTEKFLRGTAALQDAGAD
AITLADNSLATTRMSNMALGSIMKAKFGAEPLLHIACRDRNLIGQQSHLMGLHALGINQV
LVVTGDPARFGDLPGASSVFDVSSFDLIRMIKQLNEGYSFSGKPLKQRANFVVGAAFNPH
VRQFDAALRRLEKKVEAGADFIMTQPLYDRESIERIYEGTRHLDIPIFIGIMPLTSSRNA
EFLHNEVPGIRLSDEARTRMRRYEPGEEARREGVAIARELVDIAMEYFKGIYLITPFFYY
EMTVELTRYIRDRSRVVLQK
>R6H6L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:137|TrEMBL
MSLLQKALDRGSFAVTAEMAPPKGYDFSEALETAALLKGKVHGVNVTDMQSACLKASSLG
LCIHLKQAGIEPILQMTGRDRSRMALMADILSAASFGIDTMLALTGDHPVVGDCKESKPV
YDLDSVGILKMLSQMEETGTDCGGNPISGGAPVFFKGAAVTPVYEPMALQINKLRQKVEA
GAKYIQTQGVFDLDSLKRFLEAVDRAEIHVPIMAGIIPLKAAGMARFMNENVPGIAVPQT
MIDRLAEAAEEGKAKGVKGLPGKLGIEMAADLIRQIKEEALCPGVHIMAIGAERNVPTIL
EKAGIEVEI
>A0A3B8QG31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
MKVIDHIHAAKGKTLFSFEILPPLKGTRIDDLFGTIERLVEFGPKFIDV
>A4EE03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseobacter sp. CCS2|TrEMBL
MTVPSVSFEFFPPKSLEGSFRLWDCVNTLAPLDPTFVSVTYGAGGTTRQLTHEAVTTIHK
TSGLTVAAHLTCVDATKAETLDIAKGYADAGVTDIVALRGDAPKNVEKFSPHPQGFDSSV
ALIEGLAALETFNIRVGAYPEKHPEAADQATDIAYLKRKFDAGATSAITQFFFEADTFFR
FRDACVKAGIDAPIIPGILPIENWTGTQRFAQQCGTHIPQVVHDAFSNATRDGTTELLAT
AIATELCDDLLQGGVEHLHFYTLNRPELTRDICHALGVTPKVRLQNVA
>A0A250KFY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella melaninogenica|TrEMBL
MSNNITDIKQLLNDETGEKHFSFEVLPPLKGNGTASLFRNIDQLKEFNPSFINITTHHSE
FVYHEREDGLLERQSIRRRPGTIAIAAAIQQTYGIPVIPHVICSGATKEDIEYELLDLQF
LGIENLMLLRGDKAREDRMFKPTKGGHSHTTELIEQVNSFNEGVFTDGSTMKHPGKPFVY
GVACYPEKHEEAPNLEQDLRYLKMKQDLGATFAVTQLFYDNEKFYNFVDQARKIGVTIPI
IPGIKPFAKLSQLNVVPKTFHCDIPEELAGLALKCNSDEEARLLGIEWAVKQVKDLYVHG
FNNVHFYTVSAVSSVHEVMKRLEESGLLQKNS
>A0A354S6Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
MKVTDHITAANGKTLFSFEILPPLKGTRIDELFGTIERLMAFGPKFIDVTSHREEFIYKK
RENGLLEKVHTRKRPGTVGICAAIQNQFKIDTVPHVICGGFSREETEYALIDLHYLGIDN
VLVLRGDALKAEGAFKPEPHGHTYAIDLLKQVSDLNKGHYLHDEVENSNPSNFCIGVAGY
PEKHFEAPSLNTDIKYLKAKVDAGAEYVVTQMFFDNQHYFDFVAKCRKANIHVPIIPGLK
PIATASQLTTIPRNFHLNLPDDLVEAVEAAKTPAAVKEVGIQWCITQSKELMAKGAPVLH
YYTMGKADATEKIASALF
>A0A1S7BA26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plantibacter flavus|TrEMBL
MTMTEPACPGRTPFSFELYPPKTLDGGIALARTVEHLAAAGPEFISVTFGAGGSSRTASL
DVLRSIRTSTSVDPMAHLTCVGSTHAQASRLIKDFLDAGVHSFLALRGDPPAGAVEGDAF
LGDLASAAELVQLIGRVSAEHEPYAEGSLVGLPGAVQLGRRHRPRIAVAAFPNGHPRSRS
TTQDLDTLLAKQAAGATLAITQLFFHADDYLAFVERARRHGVTMPILPGVMPITSPARLR
RVLELSGEALPSDLAIALEVEPDEAGRIDIGTDYSARLIRDVVAGGAPGVHLYAFNQHRT
VLDVLHRAGIPVQGGRPVRHPIPDPLTSKDAR
>A0A829BNC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mutans SM6|TrEMBL
MSRLLDKLKTDILVADGAMGTLLYADGLESCHEYYNISHPERILAIHQAYIAAGADIIQT
NTYGAKRHRLKSFGHDKEVKAINQAAVHLARQAAGDNTFVLGTIGASHGLKHCELSLEDI
ISQTVEQARFLLETKQIDGLLLETYYDIEELEAALKALRPLTDLPIITNVALHEPGITEN
GRPLVEAFSNLVMLGADIVGLNCHLGPYHMIQSFKQVPLFAQSYLSAYPNASLLSFSSDD
NETPYHFSQNADYFEYCAKLFVEEGVRLIGGCCGTTPEHIKAIKRGIRGLKPIERKVTTP
LISQEDLIYEVEKKESLVDKVKKGITIIAEIDPPKTLAVDKFVDGVKALDEKGIAAITLA
DNSLARTRICNLSMASMLKDEIATPFLLHLSCRDHNMIGLQSRLLGMDLLGFDHILAITG
DPSKIGDFPGATSVYDATSFKLLSLIKQLNQGHGYSGASLKKATHFTVAAAFNPNVKNLS
RTGRLIEKKVAAGADYFITQPVFSETVIQELSEVTKPYEQPFFVGIMPITSYNNAVFLHN
EVPGISLSESFLAKLEAVKDDKETCQKVALAESKKLIDAVLAHFNGIYLITPFLRYDLTV
ELIDYIQVKTATVAKKRI
>A0A831SSA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecochloris aestuarii|TrEMBL
MLVKEILSSATEPVFSFEFFPPKKHEDWDKLFHTISELIPFKPSYVSVTYGAGGSTRTRT
HDLVTRIQKETGLTVVSHLTCICSDKEEVGKVLSTYEEHGITNVLALRGDLPPDASSYEE
ATKDFPHAIDLVRFIRNNFPSMGIGVAGFPEGHPQTPNRLAEIRYLKEKVDAGADYIVTQ
LFFDNRDYFDFVERCALEGINIPIIPGIMPVTTRKGLIRMSELALGARIPASLLKQVMEA
PDDETVAEIGIEWATRQVQELIDNHIKGIHFYTLNHAEATRQIFHNISQAINE
>A0A8E6B5E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Telmatocola sphagniphila|TrEMBL
MRKDEFLHRLSEEVLLGDGALGTMLGDLGVNRDMAYERLNASDPDLIRRIHQQYIDAGSQ
LIETNTFGANRLRLGTTEGSTEIADLVRAGVALAREAASSKAFVGGSVGPLGPFDTKAFS
DSEIESIYAEPIIALAESGADVLMLETFSDLRQIQLAIKVAKQKTDLPVIAQMAFHEQGH
TQHGVSVLAAMEAMLTAGADVVGTNCGRGVRCVVHAIEQMASRSNAFLSAYLNAGLPEYV
DGRYLFGAPIPYLVNSALDMVEKGVNIIGGCCGTTPEFIRKLREKLPVRKPAVRKIVPAE
VAAPVTPAVLETSPPVKQIYSDSILHRLPQSNKKRPLMVVELDPPRGLDYKPVLKRARQL
KDMGVDAITMADNPVATLHMGNLTLADIVQREAGIPVILHMACRDSNLLGLQSKLLEARI
RNVNNILALTGDPAKVGDTPGATSVYDLNSFGLIELITKFNQGVSHSGQSIGEKTQFTIG
VAFNPNGRNFAPLVDRLRRKAEKGAHFAMTQPMYDRERFDLMVDSIKSIPISVFVGIMPL
LSERNAEFLHNEVPGIVLTDEVRNLMKGFSGPTGRKQGIKITCDLIDYMLGKINAFYIVP
PPKFTEMSVEIVSHIIGKTHP
>A0A0J1IKB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus acididurans|TrEMBL
MENKFKESLLDKNTLSVTWELVPGRGANEKPQEVAIASAEQAAKGGRVHALTITDNPGGN
PAILADYLGMDILKLGIEPLVHFTCKDKNRNQMESQLYALDRANIRNLLVMTGDYPVSGF
KGRPKPVFDLDPINALQLITDMNKGLEIQGMKVPIYHKASDFFAGAAVSPFKATEAEQMV
QYYKMKKKIAGGAQFIVCQLGYDARKFHEVLQFLKVNNYDIPVVGNIYILPYGAARIMNQ
NQLPGCVVTDKLLAELEAEKGAPDKGVGARMLRAAKMYAVMKGMGFGGVHIGGHNIKYEQ
VEYIIDQGEELSKNWQDYIREFDYPQKNGFYCFEKDEKTGLNSDRPTNRANLPLDAPVNF
GYTMMRGMHALMFTPNKKLFPVMRSFYRAAEGKKKREKRLHALEHIAKVVMLDCKDCGDC
AMFDIAYLCPMSQCPKNQRNGACGGSLNGWCEVFPNEKKCIWVRAYARLKKYGEEANIDV
PPVPPANWDLYQTSSWSNFYLGKDHSAPILGIKRPESKVPQTKK
>A0A0K2FAQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus peoriae|TrEMBL
MKPDLRTVLNREIIVGDGAMGTFLYQLGFPVNTSFEELNITSPDVISDVHSQYLSAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
LELARNYEQQIDALLSEGVDGILCETFYSLDEIRIALHSVRKYSDIPVICQFAVDQVGRT
QDGFLVAEAFSVLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAKSFVDLGTRLLGGCCGTTPDHIAAISKALNRLQPPPLASKEALS
KESFQVAEQIADEGERGNGRHTSEPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHALK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYVMTQPVYDHELIAAIAEATRHLEVPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGPEGRAMGVSIAKELLDTAMEHFNGIYFMTP
FMFYEMTAELTSYVWQKSGRVQAPLFRL
>A0A0F8E5N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. 2.H.T.1A.8|TrEMBL
MLFNFREKLNSRKFLVTVEVSPPKGTMFSAPLEDACQLKGVADALNVTDNQCSIMHMSSL
AFSKLLLDQGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDHPACGDHPGSKP
VYDLDSVQLIELVRKLDSGIDFAGKRLDGGTSFCAGAVSGIDPENTLQLIKLEKKVRCGA
DFIQTQAVYDVGMFEEFMEAVNHLEVPVIAGLIPLKSLSMAEYMNKNISGIHVPEEIRLR
MKDASSPIEEGLSIASDTIKELTKLSRGVHIMPIGSHKNTPRLLSMAGISGK
>A0A5R9HCL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter thereius|TrEMBL
MFEILIQKLQEDKFLTLETTPQHEPSMHNIIEKIKKFKIDSKVDGFTCTDNPLAKLKYSS
LFAALKLQSEFKKPVIATMTMRDRNRIALQSDILGANDFDIRAILALTGDPAHMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDVSGRPFKIEPKQIFPFSVVNSYAKNFGSLEKKMHQKI
QNGAVGVITQPVFNIENVKKLLESFENAKENVEGEKRKSQLILGLFPITKLRTALFLSAQ
VPGIHVPQLWIDELEKAHTISEEEEYKVGMQLSQNLFKEINKIHPKIHLMTSNNKFDVAS
ELLS
>A0A6M8EFV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoarcobacter acticola|TrEMBL
MFETLIQKLQEDRYLTLETTPQHEPSMHNIIERIKKFKLQDRVDGFSCTDNPLAKLKYNA
LFASLKLQMEFKKPVIATMSMRDRNKIALQSDLMGANDFDVRAILALTGDPAKMSDQPHS
KGVFESNSLMLLKIIKSFNYGMDYSGHPFKIEPKQIFPFAVVNSYAKNFSSLERKMHQKI
QNGALGIISQPVFDIENAKKLLESFNIAKDGVEGDKKKAQLIFGLFPVTKLRTALFLSAQ
VPGIHVPQFWIDALESAHSISEEEEYKVGMKLSSDLFKEINKLHPKIHLMTANRFDVANE
IIS
>A0A5K7YV48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina alkanivorans|TrEMBL
MSNNGLKSGSNLEKVLKAGHFAFTGECGPPKGANVEHLKEKFEHLRGMVDAVNVTDNQTA
VVRMSSAAASAIMVAEGVEPNFQMVCRDRNRLAMMADVLGVYSLGVKNMLCLSGDHQKFG
NHPQSKNVYDIDSMQLIAMVKKMRDDGKFINDEDIDVPPKMFIGAAANPFADPYEFRIYR
LANKIDAGADFIQTQCIYNMPRFRDFMKKAVDMGLTEKAFILAGVTPMKSARMAQYMAKM
VPGMDVPEELIERLKGAGKGKQAEEGIKFAIEQIEEFKEMDGVAGVHLMAIEWEHKVPEI
AERAKVLPRPQID
>A0A5K7YVI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina alkanivorans|TrEMBL
MKLKEALEKKKFVVTSEIQAPMGDDDPEALVENLKRVRGRMDGVSVAEVELEGVVGDSIR
TCELLNQNRFDAIYQTTTRDKNRIQLQKDLTQAHETGVENLLVFTEDYRISGESLQETMF
FHVDSGKLASVLEHLKDGRTVDGRALEQRVEFIMGSGVESLWGKNVPKQGMQEMETMREL
GTGYFLTTPIFDLDQFQRFLKQVKTFAIPVIAEVMLLRNAAMARFINRHFKAGLIPDWVV
QKLDKAPDKKKASVELFADTIRGLRDICDGVHIITLGGIDKIQPYLDAAKIR
>F4KZS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O)|TrEMBL
MKVTEYFEKAQGQTLISFEILPPLKGGSMQDIFKGLDPLMEFKPPFIDVTYHREEFIYKQ
NPAGFYEKVAIRKRPGTVGICAAIMNRYGVDAVPHLLCGGFTREQTEDALIDLNFLNVQN
VLALRGDARQFDSKFEPEPGGHEFALDLVKQIDDMNHGKYLDLNIENGQRTNFCIGIAGY
PEKHFEAPNIESELAWIKAKVDAGANYIVTQMFFDNKHYFDYVANCRAAGINIPIVPGLK
PITKQYQLTSIPRHFFIDLPEALVKEFNKAETPEARRQVGTEWCSAQSKELKAAGVPCLH
YYTMGDAPTIRKIVESVY
>A0A0R3LZC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium valentinum|TrEMBL
MTEITPPAFDGHRALHSPKISFEFFPPKTEDMERSLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTIARILKETSLTPAAHLTCVGAPKGEIDDVVARYHEIGVRHIVALRGDPTTGI
GTAYHAHPDGYQSSPDLIAGIKKRYPDIEISVSAYPEKHPESPTIDADIDTLKAKVDAGA
ARAITQVFFDNDLYFRYLDRVRARGIDIPVVPGIMPMHNFKQARSFVTRAGTTVPDWLAD
KFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A317CBS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucothrix pacifica|TrEMBL
MAKHVSFEFFPAKTEKGKQNILSASKTLSSLKPEFFSVTFGAGGSDQQTTFDTVLGVQNT
SGIATASHLTCVGSSRERIGSILDNYKANNINRLVALRGDLPMGMDDPGEFQYANELVSF
IREHSGDYFHIEVAAYPEKHPQSIDHKEDLNNFVQKVKAGADSAITQYFYNPDGYSYFVD
ECMSAGLDIPIIPGIMPIGNFESLSRFSDACGAEIPRWLRIRLESYEHDPVSLTAFTNDY
ITEMCVKLIEQGAPGLHFYSMNKVEPNMQICKAVMAHFPDQFEQ
>A0A6A8V3W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQPNFEGN
>A0A5K7YTE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina alkanivorans|TrEMBL
MKSGSNLEQILRAGHFAFTGELGPPRGSNVAAVRDKAKHLVGMVDAVNITDNQTAMVRMS
SWAASLIAIEEGLEPNYQMVCRDRNRLAMQADILGASALGIRNLLCLSGDHQQFGDHPQA
KGVFDIDSTQLIGTVKKMRDEAKFLGGADIDEAPKMFIGGAANPFAEPHEWRVHRLAKKV
HAGVDFVQTQCIYNMDRMRQWVKEAVDMGIAEKVYILAGVTPMKSVGMARYMQLKVPGMD
VPNEIIKRLQGVDKKKVADEGIKIACEQIEEFKEMKGVAGVHLMAIEWEHKVPEIAERAK
VLPRPTV
>A0A8J4FEE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Volvox reticuliferus|TrEMBL
MMHLTCTNMPVEKLESALKEVKKAGVHNILALRGDPPKGQDKFEVVEGGFSCALDLVKYI
RKEFGDFFGICVAGYPEAHPDGIVDDPEQMQKNYWADITYLKQKVDAGGELIITQLFYDT
EVFIKFVEDCRSVGITVPILPGIMPVMTYGGFKRMTGFCKTKVPADILEAVEAIKDNDEA
IKNFGIDLGVKMCRRLLEAGTPGVHMYTLNLERSAVAILERLGFIDTSSVPKLLPWRHVP
KGTARASESVRPVFWSHRPKAYLKRTQGWSSYPTGRWADRSALEYNTLSDAPQFMRRHTS
TDARKEKARAAWGASLEGEQDVKAVFSKYIKGEVKLFPWSEMEGPQHAESPAETTALLDL
IAAGYLVINNQPRLNGVPSTDATYGWGAPGGALYGRAYVEIFCSPAAWESLRPRLDAAAS
VSYLAATAAGSPQGNLKHDDVVALSWGVFPGKEIVQPTVLCPASFATWKDEAFELWLSEW
AGLYEEGSASRQLLTGIHDRWLLVCVVDNDYVTGDLAKVLLG
>A0A4Y6F5T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus tropicus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A5I6S3W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella potsdam|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1I2ST15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia megaterium|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINVAGVKLAKQAAKDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLNEGVDGLLFETYYDFEELKTVLTLARKETDKPIITHVSLHDIGVLQDGR
PLADALKELEALGADVVGLNCRLGPYHMIQSLEEVPLPDRAFLSAYPNASLPAYVEGKLE
YETNEDYFVESARLFREQGVRLIGGCCGTTPAHVRAMSSALKDLPPITSKVVKMRPAVTV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRIRGEVEGLAIAKNLIDTAYELFDGIYLITPFMRYEMTEILTRYI
HDKQLVTSERKI
>L1M112|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida CSV86|TrEMBL
MTQERRYSFEFFPTKTDAGHEKLLATARTLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKAELRALLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIREETADQFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNAESYFY
FVERVQKLGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EEVITQMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>Q7ZWU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenopus laevis|TrEMBL
MVNANSSDSGTASCSSAENSKESSRCSTPVLDIERHECLKEKMRRRVEAGDRWFSLEFFP
PRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVNFCGLETLL
HMTCCNQTKEDITKHLQKAKRLGLKNIMALRGDPTGEEWEEEAEGFNYAVDLVKHIRHEF
EDYFDICVAGYPRGHPDAESYDQDLKHLKEKIDAGADFIITQLFFRSETFLTFLKDCRAI
GITCPVLPGIFPIQGYGSLRQLVKLSKLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMC
RELLDSGLVHGLHFYTLNREVATIDVLKRLGMWKEDPRRPMPWAMSAHPKRRVEDVRPIF
WASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGQELN
SEESVFEVFTYYISGEPNPNGHKVNCLPWNDDPLAPETNLLKNELQKVNKRGILTINSQP
NVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVSALIKVLKRYEPRVNYHIVNVHGQ
NITNAADLQPNAVTWGIFPGREIIQPTVVDPVSFVYWKDEAFALWIEQWAKLYEEESPSR
MIIQYIHDNYYLVNLVDNDFPLENCLWQVIEDTFKEHDRPTDQ
>A0A240U6C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax carolinensis|TrEMBL
MTAANAPATGLPVSFEFFPPKTPEGAGKLRAVRQQLYALQPEFCSVTYGAGGSTQEGTFG
TVQEILAEGVSAASHFSCIGATRQSVREELATLKAMGVKRLVALRGDLPSGYGIGGEFHY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSADADLQAFAAKVRAGADSAITQYFFNAD
AYERFVDDVRRMGLDVPVVPGIMPIMGSSQLMRFSDACGAEIPRWIRLRLQGFGDDTASI
RAFGLDVVTSLCEQLRQRGVPGLHFYTMNQSATTLELCRRLGL
>A0A5T2CAW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALADIDIPIYAGIMPITNKRQVLKISQLCRAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKKELHA
>A0A1E7PGS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALADIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A0I3SPW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella sonnei|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0D0RRR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus gallinarum|TrEMBL
MSQLLKALQNNILVADGAIGTIFYSEGLDTCPEAYNLTYPEKVQRIHQSYIDAGADIIQT
NTYGANFEKLKVFGLEHKVKEIHQAAVRIAKNAANEDTFILGTVGGFRGIKQEDLELTAI
QYHTEIQVDTLIEEGVDGLLFETYYDLDELTNIITATKRKYNIPIIAQLTALNTNYLRDG
TEINEALKTLIASGADIVGLNCHHGPHHMKESFSHIELPDDAYLSCYPNASLLDIDNSEF
KYSDNAVYFGKVAQQLISEGVRLIGGCCGTTPEHIKFIKSSVAELSPITDKNVIPITKKV
KKQSNQSTIKQNLTDKVKARPTVIVELDTPKHLDTDKFFRNIKKLDEADIDAVTLADNSL
ATVRVSNIAAASIIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILTITGDPSK
IGHLPGASNVYDVNSKGLTEIALRFNQGINTDGDALKVNTNFNIAGAFDPNVRKLDGAVR
RLERKLESGMNYFITQPVYSAEKIKEVYEATKHLDAPFFIGIMPVTSYKNALFLHNEVPG
IKLSEEILSQFEAVKDDKEKTKALSLKLSKELIDTVHQYFNGLYLITPFQSVDYTLELAS
YSKTITSNKQEAIL
>A0A3M9X4V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium japonicum|TrEMBL
MSARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A4S9W3S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEVTAPEAPQ
KVNGATNGEKHEEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A3A1VNG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A2P8KIR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. WS11|TrEMBL
MRLPLSFEFFPPKTPEGVAKLRAVRQQLYARQPEFCSVTYGAGGSTHDGTFGTVRQILEE
GVDAACHFSCIGATRATVREQLKELKAMGVKRLVALRGDLPSGYGMGGEFHYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFAAKIRAGADSAITQYFFSPEAYFRFVEE
ARRLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TELCARLASGGAPALHFYTMNQSVATLALLERLGWEG
>A0A2S0WLA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium chenweiae|TrEMBL
MTAGRTAVVNHSGCPKAMTFGPCGGVRDDASCELDARPCPFAAPDAGVVPWDGDPPPSAE
PGSLLLEAARRGPVVLTDLTIPAYDPEGLAAVTEMLADSCDAVLVGEHQNRPDFPPTLMA
ALIAQAGGVPWVTLACRDRNRLVLEQELAGLAVTGVDGVLCVTGDVRAQGVRPDVTQVFD
LDGTELAALASRAGHAVAVPESPSAVPQHLRPARLVQKEQAGAHLAVLNHVGSPDEVASF
IGASRDLGLTIPVIAAVAVYTDERSARVLQNFPGLNLDPDQVAQVLGAGDVRSAGIEMAL
REARALLAIEGVAGVNLSGLASGDGAMAGAQVKAETGHRIREDR
>A0A4S9FCR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVNVTWGAGG
STSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILALRGDPPRS
DEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQSHPEHQHA
TYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGLMPIQSYQ
ILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSGPKGFHFY
TLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSLANSAPQNRVV
VDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIPWSEEGLN
PETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVEFFCSHED
WTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIEAVSFRAW
AEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLLEA
>A0A1W5XGE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Homo sapiens|TrEMBL
GSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPIQ
>A0A2C4UHE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus toyonensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTNRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQVALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKVQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0V1J3Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella pseudospiralis|TrEMBL
LMASLEAVELKTTRHDLNSSPKKSTDKICQPLIDRIKQNMSSGRRFFSLEFFPPHTPEGL
INLLNRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCVLNFCLLDTMLHITSVQY
NEKTVLSNLERVKKIGIRNILALRGDISDDANVTATDFQYACQLVRFIRSHYGDYFTVCV
AEDLLNLKAKVDAGADFIITQLFFDEMHYFKFVNDCRKIGIVVPIIPGILPIQSYQSIMK
IVQLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVELCRKSILEQIGLWKESPVRMLPW
KKHPVHSVRCREAVRPIYWNTRPKSYLCRTRDWKQFPHGRWGDLGNPAFGDLKHYLFSCI
DQMNDSCALDMWDKELSSFEHVRDIFCNFIARTPNRHGHTVRRLPWNENHSDPAVDVLKD
ELIYYNSNGILTINCQVAVNGLPSNDPIFGWGEANGYIYQKGYLEFFASSKCTTILLNHV
QNFPSINYHAINFDGSFETLNYDEDATMALTWGVFVGQEILQPIVANAASFRVWKDEAFD
LWQRWARLYESGSIGRKLLQSIHDDHRLITLIDNDYPQPCSLSALLRAVIDECCEEKKID
DE
>A0A2V5UFM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIIDIMRGNSPTFSFEFFPPKTPEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIEAILLRYAKSAIGNILALGGDSPAGIAYDKSR
DSFQHAIDLVKFIRRFNESCAHPDHRGFGIGVAGFPEGHPATPNRLVEMDHFKAKVDAGA
EYIVTQLFFDNRDFLDFRERCALNEIQIPIIAGIMPITSISGFKRIAELAGGARFPAKLL
RALQRCQNDPETVKRVGVQYALEQCRDLLDNDVAGIHFYTLNRSDATRVIFDSLAFPRHR
NAQASSA
>A0A6P8P8L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geotrypetes seraphini|TrEMBL
MVNETQSSDTTSCSSADSSKESSRCSTPILDAERHERLREKMRRRIDSGDKWFSLEFFPP
RTANGAVNLISRFDQMGAGGPLFIDVTWHPAGDPASDKETSSMIIANTAVNFCGLETILH
ITCCNQSKDEITSHLQKAKRLGLKNLMALRGDPVGEEWEEEREGFNHAVDLVKHIRSEFE
DYFDICVAGYPRGHPEAESYEDDLRHLKEKVDAGADFVITQLFFRPETFLKFLKDCRAIG
ITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIKDVIEPIKDNDAAIRNYGIDLAVAMCQ
KILESGMVHGLHFYTLNREVATVEVLRRLGLWKEDPRRPLPWAVSAHPKRRVEDVRPIFW
ASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSSREVLLKMWGEELMN
EESVFEVFTHYISGEPNHNGYKVTCLPWNDDPLAPETNLMKEELEKVNRRGILTINSQPN
INGRSSTDPIVGWGPSGGYVFQKAYLEFFTASENVSALLKVLKNYGPRVNYQIVNVHGKN
ITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKMYEEESPSRM
IIQYIHDNYYLVNLVDNDFPLENCLWQVLDDIFEELNCPTAQEPALPLLGNVATRPA
>A0A2V5RVR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRANLPTFSFEFFPPKTPEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
GLVERIQHTTKLDPIPHLTCVCHNEEEIQAILLRYAKSAIGNILALGGDRPAGIAYDKSR
ESFQHAIDLVKFIRRFNESGAHPERRGFGIGVAGFPEGHPATPNRLVEMDYFKAKVDAGA
DYVVTQLFFDNRDFLDFRERCTLNQIHVPIIAGIMPITSITGCKRMAELAGGTRFPATLL
RALQHCQNNPEMVRRVGIQYALEQSHDLLDNDVAGIHFYTLNRSDATRIIFDSLGIPRHP
NTPVSTV
>A0A7C1A244|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MIKKITDIFKEKDRTFSFEFFPPKTPKGIENLYRAAEELNRLGPDFVSVTYGAGGSTRGA
TMDICVEIQKRFDITVMHHLTCVGHSRQELEAVISQLKDNNIKNILALRGDPPKDVENQE
PAPDGLEYCYQLNDLIREHSKDFFSIGVAGFPEGHIHCPDKDTDTKYLKIKIEHGGEFVI
TQLFFDNNIYSEYVERLGKQGVNIRVLPGILPITSYEGLLKFCDICGATVSQEVHDIFKP
LNGNEELTRKAGIEFAVKQCRDLLERGAPGLHFFTLNKVEPTKEIWNRLGL
>A0A6P3I025|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bison bison bison|TrEMBL
MVNEPRGNGSPGPRWEGSSSGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKH
IRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>A0A160KUQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter tritici|TrEMBL
MTRARFEIIPAEDIGERAMRAFPDPSAVTLTVTSLPKHGTGRTVDCAVELAGRGFRVVPH
LAARNVEGRGALERVLGRMGDAGIDEAFVISGDATSAAGSYSTSLELLRDAREIAPGLAL
DIAGYPEGHPHLSDESIERHLRERTPFIRSIVTQMCFDVDAVVRYADRLRAQGITADLWA
GVPGPVERSRLLTLGARIGVGSSLGFLRRSTSVAGGLLRGRRFDPSAFVARLESAAGERL
AGLHVYTFNELDSLAAFA
>A0A0T9MPV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia intermedia|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWNSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIATDYWNSGIRHIVALRGD
LPPNSGKPEMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMSSIFE
GLDDDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A2V5WQC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRGNSPTFSFEFFPPKTPEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIQAILLRYAKSGIGNILALGGDRPAGIAYDKSR
DSFQHAVDLVKFIRRFNDSGAHSDRRGFGVGVAGFPEGHPATPNRLVEMDHLKAKVDAGG
DYMVTQLFFDNRDFYDFRERCALAGIHIPIIAGIMPVTSMSGFKRIAELAGGTRFPAKLL
RALQRCENDPEMVKRVGVHFALEQCHDLLDNHVAGIHFYTLNRSDATRLIFDSLGIPRRR
SAQAAAIFIE
>A0A0N8SQI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. retacarpa|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>A0A8C8FRN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
MVNNVQRVDDTWRTCTKSNSSGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEADSYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIR
NYGIEQTVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMMDELDKVN
RRGVLTINSQPTINGKPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPR
VNYHIVNVHVSSSTYISLHLHLFCELNGLLD
>A0A0P7WDU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scleropages formosus|TrEMBL
MVNQVQRMDGGSQAPKSDSSGASNSGGESSKESSRCSTPLLDADRADRLREKMKRRIESG
DRWFSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKDQITAHLAKAKRLGLKNIMALRGDPLADVWEEEECGFNYAT
DLVKHIRWEFGDYFDICVAGYPTGHPEAESYEADLKYLKEKVDAGADFVITQLFFRAETF
LKFVKDCRAVGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEAMMQVIEPIKDNDAAIRN
YGIQQAVDMCKVLLQSGDVPGLHFYTLNREVATMEVLKQLGLWNEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LVKMWGEELMSEESVFEVFTNYITTQPNRNGHKVMCLPWNDDPLAPETNLLKGELEKVNR
RGVLTINSQPNINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVQGKNITNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFGLWIEQWA
KLYEDESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVIDDMFDLLDAPPVTVE
>A0A2E9YMN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MVMKSVLEAINKRGRKPFLLCDFSPPKGGNADLLLESYALNPDMFMVGYAPGKSVRLNPI
FAADWIHSKTKIPSIFTVSTRDMNKSAMQSLLLGAELMGLPNVLIVKGDKFSAEDLNLQS
EVYDFTPTELISDVKAMNERRDFRGNELTYPTRFCIGAALDLSRDWEKESRLTKTKITRG
CNFIVSQPTFDPELPSKFLSFYEKTIGEKLKIPVMWGIQMVEKDTISFANVPKWVHQDLE
AGGSSYEITIDLVKRYLEFGIDTFYLVPTIYKGGRRDYLSAQAVIEDIE
>A0A366NYS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium dahliae|TrEMBL
MDKITDKIAALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
AFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPPRKAE
YQDAVDEESDDDEDFVWATDLVKYIRKNHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVEKTQAGADFIMTQLFFDIDAYDHFEQVLREHPSGAFKTIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDALMARLDAVKGDDEKVKEVGVDIVSELVDQIRAVKSKRTTGPQGFHFYTL
NLEKAVSFILERTNLIPDKEQEDEEAVIDDATTPPVVPTVQINGLHPGSHHRPGRRQSSI
GSDPHNRVIVSSASNHAYETNPEGAGLPAEPINTRANTLAISEGEGVLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVTQAVRLWGHPKSSEDISTLFIKHIRGELSAIPWSEE
GLSPETNIIQEQLIELNTRGWWTVASQPAVNGVPSRDATFGWGPSHGFVFQKAFVELFLP
AADWKVLSERLTGPEVEGTVCFYACNGNGDFATSDDSGGLVRTAVPASTNAVTWGVFPGK
EIITPTIIEEVSFRAWSEEAFKIWGEWSRVYGRGHESEKFLKSVKDEYWLVNIIHHDFVE
TNALWDLLRG
>A0A3M5EPL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. aceris|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A229WP12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neosartorya fumigata|TrEMBL
MEKITDKIAALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSEE
YNTHGEDDSNKDFTFAVDLVRYIRKMYGDYFCLGVAAYPEGHPVDSYQDVQDPVRDLPYL
VEKTLAGADFIMTQLTYDIDAYTKFEQMLRNHESGAFKTIPIIPGLMPIHSYKILTRTTK
LSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLNLEKT
VSFIIERCGLIPDYPEDSGAVVDDDYTTAPTGAQHRSLSRRRASSVNSLPHNRVIVDRLQ
VPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQISEGQGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVSGAVARRIWGYPVSREDISALFRRHVSGDLYIVPWSEGGAEENSS
GLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFF
CPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWG
VFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRVYPRGTPTERLLEEVKNDVWLVCVVG
QDFGAGTENGSEEEQQETKWMWNVLINSQ
>A0A0U5F8U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. citri|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A120BD82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. eriobotryae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>A0A060DKF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum brasilense|TrEMBL
MTSGTPSVSFEFFPPKTEKMEQSLWQAIQRLAPLGPSFVSVTYGAGGSTRERTHNTVTRI
QKETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPETEGGVGGRYVPHPG
GYAYAADLVAGMRKVADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQFFFD
NDAYFRFLDRCAAAGITVPIVPGILPITNFARAVEFAGKCGAAMPKRFAETFEGLDADPE
TRQLVAATMAAEQCQALQAQGIKDFHFYTLNRSDLTVAICRMLGVKAKQPAVS
>A0A1C2G404|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacter thiooxydans|TrEMBL
MESQKRHARVFSFEFFPPKSEEARSAFHAALEQLAPLDPRFFSVTFGAGGSTRERTLETV
REIAGHGKAAAPHLSCIGATRDSIRDILATYKALGVRHIVALRGDLPSGMVDPGDFRYAS
ELVRFIRAETGDHFHIEVAAYPEVHPQATSAEDDIRHFQEKIDAGANSAITQYFYNADAY
YWFVDTCEARGLTVPIVPGIMPITNHRQLLRFSEACGAEVPRWIRRRLEDFGEDGESIRS
FGLDVTTALCAELLAAGAPGLHFYTLNKAAPSSVIWERLGL
>A0A2S7CKU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. corylina|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFGAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1A9B1C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plesiomonas shigelloides|TrEMBL
MSYHAHQLEALNQSVAELDGRINVSFEFFPPRSEEMENTLWQSIQRLSVLRPKFVSVTYG
ANSGERDRTHSIIKAIKEQTGLCAAPHLTCIDASEQELRCIAKDYWNNGIRQIVALRGDL
PAGQEKPALYASDLVALLREVADFDISVAAYPEVHPEAKSAQADLLHLKRKIDAGASRAI
TQFFFDVDSYLRFRDRCAAIGIDVEIVPGILPVSNFKQLTKFAALTNVRVPNWMQRMYDG
LDNDPATRNLVGASIAMDMVKVLSREGVKDFHFYTLNRAELSYAICHTLGVRPAA
>A0A8J7YSM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeum hamiconexum|TrEMBL
MSLLRENFSRKFTATGEVSPPPCPDKTLFAREVEEMKPLMGRILGVNVVEGPGGRVLMSS
LGASIYMIQHGVEPILQQVVRDKNRVALQNDLISASIFEIENVLSIAGDHPACPASDNPK
SKPVYDMDSTTLIVMLKKLNEGKLWNGKDTNYENKNLNAKTNFFIGTGLSPTSSPLDGEI
YKVKRKLIAGCDFFQTQGVFDIEPIINFLNLYEKTIGEKISDKILVGIVPIWSYGMMKYL
LTLPGIVIGEKFRNDVNEARKKQKETGQKGLIEEIGVNLCVDLVDKIKGLGVKGVHIMPV
GNLHAMKEILDKSGL
>A0A729PZ24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 48:d:z6|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5I8XLQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Choleraesuis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6P5D131|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos indicus|TrEMBL
MVNEPRGNGSPGPRWEGSSSGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKH
IRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFQVFAHYLSGEPNQNGXKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>A0A099F5A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus halophilus|TrEMBL
MSQPAVSFEFFPPRNLDQSFRLWDTARALAPLAPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREQTLQIVADYAAAGVHEIVALRGDAPQGHERFTPHADGFASSV
ELIAAIAERGDMTIRCGTYPEPHPDSADSAADVAWLKRKVDAGASSAITQFFFDADTFFR
FRDACAAAGIDAPILPGILPIQSWAGARRFAERCGTSVPQWAEEAFAGAGREGEAALALE
VCVRLCEQLVAGGVDRLHFYTLNKPELVLKVCAALGIHPNGDLSDVA
>A0A2H1A4P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida auris|TrEMBL
MKISKKLEHAHSCSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYELNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALKKAHASGCQNILALRGDPPLD
GSESTGDFKYAKDLIRYIRKNYGDHFNIGIAAYPEGHPEEEDETKLLSYLKEKVDAGADF
IITQMFYDVDNFISWCSKIRKIGVEIPIIPGIMPISTYSAFIRRAKWSQIKIPQHFLDAL
DPIKEDDYAVREKGTALVGEMCQKLIDSGYVNHLHFYTMNLERSTIMVLEHLNLIEHVKD
NAVVGDELPWRKSLHPMRSKESIRPIFWQNRKYSYISRTSGWDEFPNGRWGDSRSPAFGD
IDLSATELLRQSPKRAYELWGCPQSLQELSQIMISYLKGEIKSLPWSDGPIGDDTEVLKP
ALIEMNTNGIFTLNSQPALSAVKSNHEVFGWGPKNGFVYQKQYLEFFIHKDLVHTLLNRV
EAHNAKDAHSVITYYAVDKSGSLLTNAHDDDINAVTWGVFPGEEILQPTIVEKISFLAWK
DEVYRLLDEWVKIFHTKTITELVEEDKINAFSKLLTSFGDNFVLCNFVNNDFTSGNNIIF
DLFDGLQVSSL
>A0A661FTZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTHFEKRYLHAALTELSLEIGVHDLAALQQHSHLLAAGGRVYVNAVAGEGTAARINAAEQ
IKTCGFRPVPHIAARRMQSEQKLDDYLAGFVERAGVNEILVIGGDLCEPLGPFSSALDVI
ESGLPAKHGISRIGVAGYPNGHPDIDTAVLNQALQEKLAACKSATIDPYVVTQFSFQAAA
IIDWCRATHEKYPGLPIHAGIPGPAKLGTLLRYARICGVQTSVRKMQANKDLAFELLRRA
APWEQLEAIGQYRLDTGQPLSAHLFTFGGLKETASWLQQAAKGRKGSSDVVEF
>A0A2J8H305|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio diazotrophicus|TrEMBL
MGYTHAGHIDALNQNISELSNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKEQTGLVSAPHLTCIDASREELINIADDYWANGIQNIVALRGDI
PPGGGKPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFAQASRFAAQNNVKVPSWMAKQFEG
LEDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPTR
>A0A3B9V216|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSRFAQALSMSEFVVTSELIPPKGVDLEPLFEKAEALNQVVTAFNLTESHTAKMSMDPVA
VGHLLLDRGVEPIVQMTSRDKNRIAIQASILGAAALGISNIVIMGGDSPKNGDHPEAKGV
FDLYSSQVLDAASALNGGADYMGNPLKGAPAMNIGAVVNPGASDPSAEIENLHRKIEAGA
GFFQSQAVYDVDALASFLDKADTDAVILAGIIPIKSVRMARFMNDKVPGINIPETLIAEI
EAAGDNPDRLAETSIDIAARIIRQIRPLVKGVHIMAIGWEDKIPAIIQRAMD
>A0A818R7G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MLLNQQKKGVSHYNTYQNDNGAEKISSSRFNNFKRSDSETRLLTAKGCCLESVEYISLTE
KIHERTANNDRWYSLEFFPPRTASGAANLIECFERMAVGQPLFCDIT
>A0A8D5JSN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio alfacsensis|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLNPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDATRDELINIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A3Q8IJZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania donovani|TrEMBL
MSKLISDAIAAEDVSKWYTSYELYPPRSEKAEEDMMKVLVPNFMRQSPVFLDLTWGAGGR
TSDTTMRLCKDLQHAYPDTPINMHITCTNTPKGLINEALDFAKTHGIRNILALRGDPPRG
EEFRADPDGFACARDLVRYIHDTYGDYFCVSVAGYPEGHPSRIAEDGAISDEDHQKELEY
LKEKVDAGASFIITQLFYDASLYVQFVKRCREIGITVPILAGLLPITTYAGFVRMVSLCK
TSVPSDVKKRVEELKENPDGLKEYGVEQCVQMIECIRTSGLDYHHLHFYTLNNSAQTFKV
LKRLNALVE
>A0A484T209|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|plant metagenome|TrEMBL
MSLDTEKAAISLEFFPPRDLAAQERLVRTAKQLLAVQPRYVSVTFGAGGSTRDGTSGTVR
TLRNLGCDAAPHLSCIGASRDELRQILQGYRDEGVRRVVALRGDLPSGMGGDAGELRYAA
DLVAFIRAEFGDAFHVEVAAYPEMHPQAESPSADLRHFADKVAAGADSAITQYFFNADAY
FDFLDRTQALGVSVPIVPGIMPITNNTQLTRFSQMCGAEIPRWIRLRLAEFGDDKASLRA
FGVDVVSELCQTLLDNGAPGLHFYTLNSADAPLAIWRQLGLERAAA
>A0A3T2CNE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEADVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNEGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMRKAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A4B0GL73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNEGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMRKAEEQGHANEEGMAIARELVDAICEHFQGVYIITPFLRYDLSI
ELAKYVQNKQQVQIVSK
>A0A0E8M672|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia enterocolitica|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A371R352|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrobaculum aerophilum|TrEMBL
MEIVAELTPILDREKLLARLDALTRYVEKVDIPEAPGGKPSAHSIAVGALAKQLGIEPIV
HIRLLDINMTAYKSLLGGAYLLDIKYVVVLQGDPPAEGRPVGEISTEEAVAVAKKMGFKA
GALLSLRRDYKQRLKIGADFYLALHLREAEQLADLPPVIYPYILVKTEKNFDLFERLGQT
AVSPREALELVRKLEGLAPGVVLSVPRDFQTLLGLLQEVKIRP
>A0A219CIP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFMLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVK
TGKEFTPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A1Y3M3L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter agilis|TrEMBL
MPARTYPALSYELYPPRGDDAEESLWATIRRLEDTRPDFVSVTYGAAGSNRETALTLLRR
LLTETALKPLAHLTCVGSSRAELTDVVERLIGGGVRGILALRGDAPDGVDPSEGDLQHAE
DLVRLIRHIEAPRTAQLAAGRVSVGVAAYATRHPDSPSEEHDIDVLLAKQQAGADFAITQ
VFFQPADYARLLTRARRAGVTIPIIPGVMPLTSTRRVEKLGSLAGIEVDASLLARLEGAR
SDAERRRTGVAATVELARAALDHGAPGLHLYTFNEHAAALDVLDALGLERPPEAGTVASL
>A0A1A8B7D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius furzeri|TrEMBL
MVNQVQRVDGSWLSCKSDSSGTSNSGGESSKESSRCSTPVLDAVRSDRLRDKMRRRMESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEEEEGGFNHAV
DLVKHIRSEFDDYFDVCVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTF
LTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKREESVFEVFTCYITGQLNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDAVVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRV
NYHIVNVHGRNLTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLKSCLWQVLDDMFELLDAPLETLADGMPG
DGSHGDGSHDNGTLAE
>A0A1E3VE37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer alkalisoli|TrEMBL
MSPDINPHDPGAPLEPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYERASVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLQTVRTMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMNKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRRPWQREAAPTDTLVAERLEHIREGIEENQQQMAEAAAH
HPH
>A0A2N5NQU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus gnavus|TrEMBL
MKIIDRLREDGIHISFEIFPPKTDAGYDKVIRAAEEMAGLKPEFISVTYGAGGGTSKNTA
KIASYIKHDLHVESLAHLTCASSTKDEVRSVIASLKEQGIENILALRGDISEDMVFPSED
RFHYAYQLVEEIRRHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSARQMKRSCELSGTVFPRRFQAILDRFGDSPK
AMEQAGIAYATDQIIDLLANGVKNIHIYSMNRPEVAAAIMHNISEIIQC
>A0A2T5NSH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium haemolyticum|TrEMBL
MTAQSRTFSFEFFPPKTPEGIAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLATVLEI
RSEGHAAAPHLSCIGSTRENIGAILNEYRNNGIRHIVALRGDIPSGMVAAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLNNFVRKVHAGANSAMTQYFFNADAYFRF
VDEVQARGVNIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRQRMQAYYDDSASIRALGL
DVVTELCDRLLQHGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A3V9FPW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella senftenberg|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPSL
>A0A4Y7VS32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus epidermidis|TrEMBL
MSHLLNQLKSNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKSFGLEHKVKEIHQAAVQIAKRAANEDTIILGTVGGFRGVRQEDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELTRIVTATRQKYDIPIIAQLTASNTNYLVDG
TEINAALKYVVECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDIAQELINEGVRLIGGCCGTTPEHIRYIKSAVKHLKPVKDKKVIPINKAS
SQKQTRVLKQNLTSKVKNGPTVIVELDTPKHLDTDTFFDNVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQHYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGINTDGDALKKHTNFNIAGAFDPNVRKLDGAIKR
LEKKVASGMSYFITQPVYSKEKIIQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSDDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A4Z0EUN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp. UV11|TrEMBL
MKVTEHLRRAEGRTLFSFEVLPPRKGENIHTLFSNIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRKRPGTVGICAAIKNRFDVDTVPHLICGGFAKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFQPHPDGHTYACDLIGQVADLNHGRYHDHDEQYQPAGAEPVLCTDF
CIGTAGYPEKHFEAPNMGSDIRFLKDKIDRGADYIVTQMFFDNEEFFKFEKRCREAGITV
PIIPGLKPLTTKSQLTGLPRAFFLNIPEALAEAIHQAKDNAAAREVGIEWCLNQSRELMA
HGVPCLHYYSMGKSEAIRRVAAGLF
>A0A1R3EQ77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio lentus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQIAAL
>A0A2J0YXD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium meliloti|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYERAAVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGVG
PMASAKTARWIRSNVPGIHIPDSIIKRLEGAQDQKKEGKQLCIDIMNEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLRGRKPWTREAAPTDALVAERLEHIREGKEENQQQMAEAAAH
HPH
>A0A4T0G330|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia ichthyophaga|TrEMBL
MKITDKLLAAEREDRLWWSFEFFPPRTAQGMTNLVDRIERMRRLGPEFIDITWHSGGRTA
ELTTELVKTCQASIGVETCMHLTCTGMPREKVINALEEAKKNGCTNVLALRGDPPRGQTE
WYPHPNGFTYAVDLVKHIKSVYGDYFEVAVAGFPEGNLQYKHSSDKALEMQYLKEKVEAG
ADLIMTQMFYDVDNFIDWCKQVRKAGITVPIVPGIMPIQTWNGFQKAVQMAQANVPESWM
QQLEAVKEDDASVRKVGTKLVSQMCKQILDANIGIRGLHLYTMNLERGPKMILQELNLIP
QTQILNPLPWRPSLTPMRRTENIRPIFWANRQKSYLSRTEMWDEFPNGRWGDSRSPAYGE
LDGWGPTINLKAEEALEIWGEPSKYDDICSLFSRFCLNDLKALPWSDQPPARETSVIDRQ
LAKMNDIGFFTINSQPAVNGARSDDKVHGWGPKGGYVYQKAYLEFFVSPDNLDKLISRIE
LNPMMTYYAVNKRGDLRTNTHSEGPNAVTWGVFPGSEIVQPTIVEAVSFMAWKDEAYELG
YQWSDMYKHGSASQQIIRQIMDTHFLVNVVHNDFKNGQDIFKPFINEFDKKTVLNDTIKN
>A0A0K4PUI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPESGKPEMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A6N9UNS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces coelicoflavus|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSAAWDTDVAHFVD
KCRAGADYAITQMFFQPDSYFRLRDRVAAAGCDTPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A659QP02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Wilhelmsburg|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3D0FK13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MIKDLFSQKQTLSFEVFPPKKDDEFTNAQNVLHQLSELQPDFISVTYGAGGSRSKRTVEL
ASFIQNSLHIPAVAHMTCVGSSKEDILTVTDDMKQAGLSHVLALRGDRPTWMDDAQFENR
AFAHASDLTRFLKEHTDLEVAGACYPEKHFEAESLDSDIAYLKEKQEAGAAFFITQLFFE
NDSFYRFLEKKNHAGITLPVCAGIMPITSAKQLGTTVTLSGSSVPKELADIIATYGENPE
DMRKAGIDYAIRQILDLKQHGADGIHIYSMNKPKTTRTIVEAIR
>A0A1X1AGW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFYLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1E3EGE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium elkanii|TrEMBL
MTETISSVPNAPRAPKAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTITRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAGIKRRHADIEISVSAYPEKHPEAKDFDADIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A0D0FC74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldibacillus thermoamylovorans|TrEMBL
MGLIQDLEKQILIADGAMGTLLYSYGIDRCFEELNVSNPQEIERIHREYIEAGAKIIQTN
TYGANRIKLARYGLENEVQEINAKAVEIAKKTVKTSGKPVYVLGTIGGIRTFQKAIFSTN
DILQSFEEQLDILLKEQVDGILLETYYDLDEIKAVLEVARKKTDLPIMANVSLHEKAVLQ
NGTPLAKGFNQLIDLGANIVGLNCRLGPYHMIQPFEEIPIPNGAFLSA
>A0A0R0KJF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycine max|TrEMBL
MKIIEKIRAASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVQHIRAKYGDYFGITIAGYPEAHPDVIESDGLATPEGYRNDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKVSRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALSDYQFMRPRARDKKLVEEWAVPLKSVEDIYERFRLYCLGKLRSNPWSELDGLQP
ETKIINEQLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKL
DALVDKCKDRTSLTYMAVNKDGSWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFNVW
KDEAFEIWSRGWASLYPEDEASRKLVEEVGF
>A0A0N0GJC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. morsprunorum|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A6P2RVD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVV
>A0A084WNA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles sinensis|TrEMBL
MASRTPANEAEEQVENLHTKLATIFDSPSETVPSVCYSIEISAKDDFHMELLEQLSPKPI
FCSLPWISDETLRYEDNFLQAPSLRLSKELQKARYTVVNHLSCYNLTEHQVEKFLATGVR
NLFIIRGDTVTPGQKFPKAANLVQHLRDREQANGGVKLTIGVGGYPYGHSQSRSDTEELQ
YLQAKVAIGVDFLLTQTLYDADSFFRYRERCRNVGITIPIIPGIYLPNSYQHLQAMLKIT
NITLPPLLRASFDSHADDTPDQFEAFVVDHFVGVVRNLVQPNDATNEPVRLVHFFTFNKL
RLLQQVLFKLKNVL
>A0A6J7CDD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSQMREKLENTNDLVFTAEFPSLDGGGMAKVEKNAARLAPWFVGVNATDNPAAHAHASNT
ASAIAMKMHGIEPIMQIVCRDKNRLAIQADMMGAALHGIDNISLLTGDDVTAGDEPESRR
VFDIDSTQAINIARIITTGKYLSGRKIDPAPDFYISAVENPAAPPFDYRIERALKKYRAG
AKYLQLQICYHSDRLEKFCAGVAKIAPDLKLIPTIVLVKSAKPMSFMHDKVPGIDIPQDT
LNRVSAAADQAEEAYKLTVELAKHALTLPSVRGLHVTDFRHDDSLDRFMYDLGQKPRN
>A0A2B5GSC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQTGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A174R1A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea longicatena|TrEMBL
MKISDILVEKTPHLSFEVFPPKTDAAYEGVLKATEAIAELKPSYMSVTYGAGGGTSKNTV
KIASHIKDKYNVPSLAHLTCVSSTKEEVHQVIDQLKASGIENILALRGDIPQESEFPLPN
HYQYAYELIEDIKSQGDFCIGAACYPEGHVESEHKKDDIAHLKQKVDCGVDFLTTQMFFD
NNILYNFLYRAREKGVTVPVIPGIMPVTNANQVKRILSMSGTNLPERFKAIVDRFGDNPK
AMQQAGIAYATDQIIDLFANGINHVHVYSMNKPEVAAAIQANLSEILNK
>A0A2N3R9V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium asteroides|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLMPDFISVTYGTGRRSDRTATARIAKTIH
TEYGIPAVAHLTAQYADREVIDQALDMFDDAGVAAVLALRGDSVEGREPAGVFDHASDLA
SYIRSRRPNLSIYGACYPETHPEAASPEEDMEHLRIKVDSGVDHLVSQLFYDNADFLDFL
DRARAAGIQVPIEAGIMPITNEGQVRHMSEVCKARIPAAVESILERWGDDRASLREAGII
YASQQIADLVAHGVDGIHLYSMNHSGVTRRIWHNVRHLFHQVGAKEEPVSSQK
>A0A486WZ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Stanley|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J6LNB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRSTFSFEFFPPKDAQGEARLWQAMEGLTSTAPDYISVTYGAGGSSRDRTIAITSEITSR
TKIPTVAHLTCVGSSKGEILDVLNRYRDAGIKSILALRGDPQGGPSAPWVSTPDGFTHAD
ELVSLAAEFGDFTIGVAAFPDGHPASGGNFDKDISTLLRKEDRGASFAITQFFFGVEKWS
SMVNRLAEAGSSLPIIPGILPITNFKQLVRMSDLNGTPIPAEILQIFAPLENDPDGVRKA
GIEIATKSCQELLAAGAPGLHFYTMNSSTATREIYTNLGITR
>X5EQ08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A5Z3F7J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J7GBT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSAPTISFEFFPPKDVPGEERLWRAIEALGPIAPDYVSVTYGAGGSTRDRTIAITSEITH
RTHIPTIAHLTCVGSTQEEILHILTRYRDVGIKSILALRGDPEGGPRAPWVSIPGGLNHA
DELVALASEFGDFTVGVAAFPDGHPASAGNLDKDIDVLIRKEDLGASFATTQFFFDATKW
SSLVARLEERGSSLPVIPGILPVTNVKQLVRMSELSGTPIPDAMRKRFEAIESDADAVRE
LGVEIATELCQKLLAAGAPGLHFYTMNTSTATSQIYKNLALKR
>A0A1X1FH96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus parabuchneri|TrEMBL
MSLTELFKHKTVFSLEVFPPKKTSPTEAILPTLTRLQSLNPDFISVTLGAGGTDHCDGTV
EIANLIQNKLNIPAVSHVPGLYQTKEQVLALLDRLDSINVKNILALRGDRIAGKQPAGDF
THANELVKFVKEQRPDFTVASACYPNCHTEAAGFVDDLAHLKEKVDAGADHLISQLFFDN
QAFYDFKEKTEIAGINVPIEAGIMPCTNKNQIERITQISGVPIPKKFAAIMDRYQDSKEA
MLDAGIAFAVDQIIDLVSQGVDGIHLYTMNNSKIAKRIWDETESVFAASDLSKQKANS
>A0A1E3A2Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eisenbergiella tayi|TrEMBL
MIKDLFAEKKQLLSFEVFPPKKEDEFANAFAVLDSLAVLQPDFISVTYGAGGSKSKKTVE
IASYIQNQLHIMALAHMTCVGSKKEDIDAVTAQLKEVHVNHVLALRGDRPSYMSDEQFDS
RHFSHAADLITYLKGETDLHIAGACYPEKHYEAADLESDLLHLKEKCDAGAEFLITQLFF
DNEAFYKFLEKSRNAGITLPVCAGIMPITSAKQLGTTVSLSGSAVPKQLADIIATYGDDP
ADMRKAGIDYAIRQILDLKAHHADGIHIYTMNKPKVAQEIVSAIQ
>Q9VTI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila melanogaster|TrEMBL
MHAIQVPAGGSSPGAASYIPCVTFAPDQNESVVTKQRIGTLVAERTAQHRLFYGIEVMAS
DPSGRPTCLDFNHFLPLLPTFVSFVWLSQRYWDVEPVGQVESLQMAQHLATRIPVLPHVS
AYRMSRQRLDQFLALNFSSLLAVRGDRVHEDQDFSISYPMVEQSIRQRGETISVCVGGYP
EGYTSLGDIPQNSAKNMEFLKAKIDAGADCIITQLCYRPEVIVQFVKDCRAAGISVPIVV
GLMSHESFRSYSMIEQITGVHLPDDLREQLDQLHSAHMKDMKSDQDLIRRFFVSLTVRTI
RNVLDADVGVWGFHFFTLNRFKSVQAVLQELRDLDLLKDSEKDKKGYEK
>W7RLA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sphaericus CBAM5|TrEMBL
MGLLERLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESSVQRFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLNDI
LKTVEEQASVLLAGNPDGLLLETYYDFEELTATLKMLRAKTNIPIIAQVSMHEPGVLQNG
MSLNIALHELEILGADIVGVNCRLGPYHTIQAFEGVELPEKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVSEKYAKPAKIEI
VRDAEPAKYEPLHEKVKRERSVIVELDTPRHLEIEGFLEGAKQLYEAGADVVMMADNSLA
SPRISNIAMGALLKSTNGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDVLAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKMIEIYEATKHLQAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSEDALARMKACGEDKERATLEGIAIAKELVEVAAQYFNGIYLITPFLRYDVTLELMKY
IEQLDEQKKGVSING
>A0A3Q9LFV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Moero|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2H1IA29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MEATTATQVLDDFSLEMTGKDVPSLQQAAHAIPQGTRVNVTFLGNENLQMRVEAAKEVLE
LGFVPVPHISARRLKSETELREFLDALQQAGASDHVFVVGGDPASPEGPYSDSLSVIRTG
LLQEYGVTEVGIAGYPEGHPDIGTDTLWEHMEAKSASLAEQGMGQVVLTQFAFDAEAVVA
WVHEVRGRGIEADLRIGTPGPAGIKRLLGFARRFGVGTSAGIAKKYGFSLTNLLGTAGPD
RFLKDLSSYESITSASSGVKTHFYTFGGLEATAEWVQDFTAQA
>A0A1G8FQU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides ovatus|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEIAKIIY
>A0A815FHI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adineta steineri|TrEMBL
MYNNEIDPDAGHHPHVFKRAESDSGLQAKGCCLQTVKYVSLTEKIEKRIASNDRWYSLEF
FPPRTPSGAANLIGCFDRMAVGQPLFCDITWHPAGDPASNKETSSMMIANTMLNYCGIDT
MLHITCYGAKKEHMLEYLYKAKEFGIRSLLALRGDPPVGEEWDPKKSDFRYGVDLVKFIR
QHFGDYFVICVAGYPQGHPDSTSYEDDLGYLKEKIDCGADFIITQLFFKPETFIKFESDC
RAIGITCPIIPGIFPIQGYASLRNIVRLAKLDVPKEILACIEPIKENDEAIRNFGVQTCL
DLCSALLDTGKVHGLHFYTLNREFATIEVLKKLGLWLEEHPLRALPWKKTSNSHTRSKEN
VRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGMLTDYHLFYMKIDATRDELLDEW
GRELTCEEDVWRMFACYIGGEKNTSNKVVRHFPWTDEELSLETTLIQNNLIEFNRRGILT
INSQPAVNGKPSSDPIVGWGTSNGYVYQKAYLEFFTSADNIPALRAVLKNFPSVNYHFVN
KSGESNETNTVDEQPIAVTWGVFTGREIVQPTVVDPVSFMIWKDEAFSLWTERWGKLYEP
ESRSHAIIEQIANTYFLVNLVDNDYVEGSCLWTILDSMFEYQKVSKTNGNI
>A0A109E7P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cenocepacia|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DTRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAAVATRTICERLAV
>A0A7H9VPW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILHETTLTPAAHMTCVDAARHQVDAVIQEFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A3S3BPE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPEAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLRGRQPWQREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A8C4XS72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falco tinnunculus|TrEMBL
AGDSLCSGIGAGDSCLWRYHTCTAGSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERL
REKMRRRQDAGDKWFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDK
ETSSMIIANTAVNYCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPIGEEW
EEEVDGFNYAVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVLAGADFI
ITQLFFRSETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIE
PIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTDVLKRLGIWKEDPRR
PLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYL
FYLKSKSPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETN
LLKEQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVMAL
LKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKD
EAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNS
PTQE
>A0A2E5HPX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MTNTNAFLAALERGPLVVDGAMGTQLYERGVFINRSLEEVCLRNPSLVQQIHEDYIAAGA
DLIETHTFAANRLKLAKHGLEDKLVELNRAAVQIARRCADRGKVLVGGAIGPTGAVPGVI
SDAELERVRDAFKEQAAILADGGVDVFVLETFRLLSELRLAVQAVQAVSSLPIIAQVAFD
GEERTSEGADPEQVFTLLRDLGVDVIGANCVEGPHQLFSVAEKMVGRGIPIAIQPNAGYP
KIQEGRHIYMATPEYFGVYARRFFKLGVSLVGGCCGTSPEHIRRIVGAARMMGGGRVEAR
SEVSVVSTPDRERYEGVEPTPTAEKTGLGAAIARVYHDRVKAKEPVPVGPESFVVSVEVN
PPNGLDPSKALAAARLLREGGVNVVNIADGPRASVRMSNQALGLLIQRELDMEVILHVCC
RDRNLLGLQSDLLADHVLGLHNLVIITGDPPKMGDYPHATPVFDVDSVGLLRIADNFNHG
RDLAGKKMDPTRFLCACGAEPAALDYDREIRRLEQKREAGAEFIMTQPVYDPEILHRFIR
DTRHLDMPILVGLLPLASHRNAEFLHNEVPGMQIPQDIRDRMQKVDRGPAARAEGVRIAQ
EALLGVVDDVVGAYIMPPFGRYSLALDILTCVGYTRPESQDKAS
>A0A7V2TQD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MPFREVYRQAKPAVSFELFPPKTDEGRASLFAHLPELASCRPAYITCTYGAG
>A0A2K3DA10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlamydomonas reinhardtii|TrEMBL
MKLIHKVEEKMKKGETFFSFEFFPPRTEEGVENLFERLDRMVAYGPVFCDITWGAGGSTA
DVTLDIATRMQNLICVETMMHLTCTNMPEEKLESALHEVKKMGVQNILALRGDPPKGQEK
FEAVEGGFNCALDLVKYIRKQHGDYFGICVAGYPEAHPDGIVDDPEQMKKNYWADIAYLK
QKVDAGGDMIVTQLFYDVDVFLQFVKDCRSVGITCPILPGIMPIMTYGGFKRMTGFCKTK
VPAEISDALEAIKDNDEAVKAYGIDLGVRMCRQLLASGEVPGVHMYTLNLEKSAVAILEQ
LGLVDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSNRPKAYVKRTQDWDSYPAGRWGNTR
SPAYGALSDHQFMRRHSTGEARREKARAAWGAAPASVDDVKQVFVKYIKGEVSLLPWAEL
DGGLTAEAAAIREPLAALNANGYLTINSQPRVNGVASDDAVHGWGGPGGYVYGKAYVEFF
CSPEAWATLRAKLDAAPSITYLATTAAGSPAGNMAPDAVNAVTWGVFPGKEVIQPTVVCA
PSFAVWKDEAFELWTSEWGALYEEGSAARDLLAGIKDSWVLVSVVDNDYVAGDLFGVLLG
>A0A701SI82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella muenchen|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>M1PUL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina mazei Tuc01|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRFSASLEDASQLKGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDYPTCGDHPGSKP
VYDVDSVQLIELVRKLDTGVDFAGNKLDGGTSFCAGAVSGIDPEKTMQLIKLQKKVKCGA
DFIQTQAVYDIGMFEEFMDAVNYLEVPVIAGLIPLKSLGMAEFMNKNISGIHVPEEIMLR
MKDASSPMEEGLLIASETIKELTKLSRGIHVMPIGSHRNTARLLSLAGISQK
>A0A7V4WKD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Caldatribacterium saccharofermentans|TrEMBL
MEPFLEFLKGTRVCLCDGAMGTELLRRGYPKDAPLELASITHRDLVRGIHEEYLASGAQL
LETNTFGANALKLSLFGLEEKVEEIVLAGVRLAKEVARGRAYVLGSVGPLGKPVGKGLGV
EDDRARECYRQQIGALLEGEVDAVLFETMVSPHEVALAVEVLRSFDRNIPYLVQFSFFPD
GTTPSGDSLLRVLEFLKSLDACVVGINCGSGPHEAVHILEQFSQHLPGPFSVQPNAGYPQ
IVQGRIVYGAPPEYFASFAGTFVRLGAKILGGCCGTTPEHIRALAKAIEHLEEGTTLEVL
EPEREAVSEAPFPPSTFAEKLGKRFVFTVEITPPKGTNLEGVKEGVRLLKKAGVDAVNIS
DSPMARVRISPIALAHILREELGVESIVHFTCRDRNLISLQSELLGAAALGVQNILALTG
DPPSVGDHPFARPVFEVTSEGLVLILSRLNSGVDFAGNPLGKATNFTIGVALNLNAQDLS
QEVERLKRKIDNGAHFILTQPIYDPRDLERFFDLFRGSLPPLLGGILPLRSFRHAEFLHH
EVPGIVIPERLRARMAQAEDPKREGVAIALEVIRGIRDMVAGIYLMPPFERYEMAVAIIE
AFRREEGQDA
>A0A8H5T683|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium denticulatum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGGLSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLSSDSSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A3A6G0E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium TM07-2AC|TrEMBL
MKIIDRLREDGIHISFEIFPPKTDAGYDKVIRAAEEMAGLKPEFISVTYGAGGGTSKNTA
KIASYIKHDLHVESLAHLTCASSTKDEVRSVIASLKEQGIENILALRGDISEDMVFPSED
RFHYAYQLVEEIRRHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSARQMKRSCELSGTVFPRRFQAILDRFGDSPK
AMEQAGIAYATDQIIDLLANGVKNIHIYSMNRPEVAAAIMHNISEIIQC
>A0A653AH44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Paludibacter sp|TrEMBL
MSLVENLKSSKSTAFSFELLPPLKGNGIEGVFRTINTLREFDPKYINITTHRSEMVFKET
SAGLFERVSERHRPGTVAVAAAIQHKYKIPVVPHIICSGFTKEETEYVLIDLKFLGINDL
LLLRGDKAKHEKEFSPTGHKYATELQQQVNRFNEGYFLDGSKMKVIDEPFSYGMACYPEK
HEESPNIDNDLYWAKQKVDNGAEYLVTQMFFDNQKYYDFVEKAREIGIDVPIIPGLKPIT
LMNQLTVLPKIFKSEIPEAFAAELRKCKTDAESIEVGVEWCTMQAKDLIAHNVPSIHFYS
LMATESVKRVARNVY
>A0A2N2AWJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-7|TrEMBL
MMVISLELVPNNEELLSQQLSYTKSNYPEIEGINIPDLIKFDMRSWDGCKVAKKSYQRTI
PHIRAMDIDLEEPLPMAKVLIENDINEVLILTGDLPQDMNKKIYHSSTIDVIRKFKTELP
HIKVYGAIDQYRDSFKSEMLYIKRKLYAGVDGFFTQPFFDIRFMSIYEEMLSGTNVYFGI
SPVLSAHSQNYWHAKNNVIFPEGFSTEYNWNIGFAKNAMEFADSKNRNLYFMPIKTKLEL
YLHSVFR
>A0A398CX27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella faecalis|TrEMBL
MRPDLRSALSLSHRPLVGDGAMGTFLYQLGFPVGVSYEEFNLLKPGVIGDVHRRYVEAGA
EVIETNTFSAQHGKLSKYGLEKKVEAINAAGVAIAREAAGDRAYVVGAIGAIRAGRRRAV
RTATIKREYEEQIGAILAAGVDGLLLETFFDLEELSLALGLIRAKSDLPVICQFAVEDTD
RTHDGVLLGEAFRRLKGEGADVIGFNCRSGPNAILRAMQTIPRDLGASLSAFPNAGIADL
VDGKVVYSATPEYFASSALRFADLNARLIGGCCGTTPDHIAAIAKALRDYSPSPERENGN
AGGVDSAVKTGAGAEERPVYDGGRFGDEPSIVELVKHRHTVIVELDPPRDLDIAKFMAGA
KALKEAKADALTMADNSLAVTRMSNMALAALVKERIGIRSLAHIACRDRNLIGTQSHMMG
FDALGIDHVLAVTGDPAKFGDLPGSSSVYDTTSFEIIRMIKQLNEGVAFSGKPLKQKARF
VVGAAFNPNVKHLDKAVQRLEKKVQAGADYIMTQPVYDAGLIERIAEATKHIPIPVFLGI
FPLASGRNAEYLHNEVPGIQLSDEVRERMRGLEGAEGRAEGVRIAQELLDTAMKHFNGIY
LMTPFLSYEMTVALTAYVKEKSAVIAQAGV
>A0A523A6M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKPNFNEYIRERVLLADGAIGTYLFAKGIEPDKNIEQLNLGESDLVYSMHEEYIRAGSRL
LTTNTFGANRLKLEAAGLADKTRQINQAGVELALRAAGSDIYVAGSVGPSGADFPLTDAA
GLAGLVGLSGQDGDVIRAVFREQIEALLDAGVDLLVLETFSHLDELLLAIRISRELMADI
PIVANMVHPQQGQSAAGRDALVCGRAALKAGANVVGSNCGRGVRAMLTAIENLSSLGAET
PLAAFPNAGFPEIVGHRLIYPAEPAYMARALGDMIKAGARLVGGCCGTTPTHIQEFGKRL
RLKRRPLSRINNKGPSDNSQEDQPLNAAKPGALLTGFAPNRLPILVELDPPTNLETSGVL
RGAEALAQAGVDAISLGENPLAVLRADNISLAHHIRRELGIATIAHLSCRDRNTLGLQSQ
IMGAHLLGIDGILAVTGDPISTGDQPGASGVFDVQSYGLIHILNQFNQGRNLAGKDLKGT
CNFSIGAAFSYRPSNPDPQISRLERKAALGAVFAMTQPFFSAIAVEEMLERTAHLDILIF
PGIFPLVSARNADFLHHEVPGITIPAELRRKLWSYEAVEDQRKVADDFTRKLLAAICPLI
DGLYLISPLNKWEITARLTQEIRQAGWQGRGRTTSKLNE
>A0A7X5SG66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus polymyxa|TrEMBL
MKPDLRTVLNREIIIGDGAMGTFLYQLGFPVNTSYEELNITSPDVISDVHGQYLNAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIAKAAAGPEHYVVGAVGSICGGKRLNISK
LELSRNYEQQIDALLSEGVDGILCETFYSLDEMRIALHSVRKYSDIPVICQFAVDQVGRT
QDGFLMAEAFSTLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSMPLSVYPNAGLADYVD
GHYVYGASPEYFGECATSFVDLGTRLIGGCCGTTPDHIAAISKALNNVQPPPLATIEALS
TESIHVVEQTANEGGRGNGRHASDPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHVLK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYIMTQPVYDPELITAIAQETRHLEVPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGSEGRAMGVSIAKELLDTAMEHFNGIYLMTP
FMFYEMTAELTSYVWQKSGRALAPLFRL
>A0A7J5VPM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MPLLQSSDIFRESLFKTDEFTLTFELVPGRGSGGKQLEGTLRFAEEAKKDGRIKALSITD
NPGGHPALAPTSLGLEIQALGIAPLIHFSLKDKNRNMAESQLFECHRHQLLNLLVLSGDY
PRYGYQGQAMPVFDLDSPQLLALIQRLHCSLPLERQAPGGLMPLPTMDFLAGCVVSPFKI
TEAEQIFQYAKLLTKVDAGAHFVISQLGFDMKKYEELLLFSRQNDLSVPLIASVFIPGLK
VAEMMIQGKVPGIVFPESLLNRMRQEKTTQDKGEEARLLRGAKMVAILKHMGYAGVHLGG
NNLDFSKIAFLLDQAESYARTADLEELHQEVDFPAPASWYLFPKSGRQLDRPRSSIAAAA
LYNINQQIHDSAFKPEGLLFSLARAISLRADPHRVMRRLYTTCEQLVKAILFRCRMCGDC
TLAESNYLCPQSGCPKKMINGPCGGSLYGFCEVYPGERLCFWVKVYQRHPISSPKKLSLR
SPPLPPKDWALQGSSSWLNYFTGRDHKKLGPESSKPKQ
>A0A523A7I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
METVTKSVTKSASRLEKVLRSGDFAVTGELVPPKSANPEVVREKARLLRGLVDAVNITDC
QTAIVRMSSIGAGLLTQAEGVEPIIQLTCRDRNRIAMQSDILGAAAFGLKNLLCLTGDHQ
KFGNHPGAKGVFDMDSIQLLGVMKNLRDEKKFQCGEVIKDHEPRFFLGCAANPFAGPNEP
ARAARLAKKVASGADFVQTQIIYNVERFAKFMAAVRELGLDQQVFILAGVTPPRSLGMAR
YMKNFVPGLDVTDEVLKRMSGAKDKEEEGIKICVEIINQCREIKGVAGVHIMAIEWEAAV
AEIVKRAGLADRPGLEPDLEAEKVPIPAPIIERLTVGQPAAVDKPVTATLEVAKTIDFQS
AAEAAETAETTEAAQFAQAGEAAAAELAAARREAAKIIAAARAEAAAIGVQAAVPVPASV
PASVPAQAPTVAVAEITDSAQIHAQSAADAADAGEDEMNERERQMALNSVRRGLAALKKT
FGLSDDQFDAMAQFAGAEAILKREPLIGTGTSVAVIPTQPEALTVPVSAEPTPAAASPDP
VVSKAAKAQTPGEAQKAAEIKAQEEAKAQEETKAQMEVQAQAEAKAAAAVRKKAAAQAPA
AKESKKLADAQDQAPAATKVAEKTAKVVEVPAQPEVKTTTSVAPVAVLAGGELAGEKISL
AKRASKISTTDYIQNYSGAICEVSLGNAPDGVTVGGINALPFHLFEGEMKHQPLIAMDVL
DVLPEEWPTSLSRHFAEVMNNAVTWAQKCVQDYQAEAICLSLVSTDPNGLNRSAADAAKI
AAAVVKAIEVPIIIWGCGNNEKDTETLREITAIIGDRKVCLAPLEDKNYRSLGATAMAFQ
HPMVASSPIDVNLAKQLNILLENLGVPLNTILIDPSVGALGYGIEYTYSVMERIRLAALT
QEDVKLQVPFICNLGREVWKTKECRLPSDEMLGDQETRGVLMEAITATCMLMAGGEVLIM
RHPRAIALTKTLIKGLMA
>A0A2N6C752|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MFAARDRNGMVPNKQTSHRPAQTTKTMKPNIIDYMRDKVLLGDGAIGTYLYSKGLELGKD
TERLNLSEPELIYSIHEEYIRAGSQLIETNTFGANRYKLSESGLDAKIRDINLAGAQLAK
RAAGKDVYVAGSIGPSGIDFPLSTGDLSREGLQEIFGEQIEVLLEGGVDLLLFETFTHLD
ELVLAIETARTISDIAIVAQMAYPSGGKTAAGVDALTCGKAAIAAGADVVGGNCGRGVSS
LYTAIEHLAPLHDQVPLSAFPNAGFPEIVGHRMVYPAEPAYMVKALADMIKLGARLVGGC
CGTTPVHIHEFQQHLKIKRRPLVRSADIQGDDSTATKAQQDNHINGALLESLPAHRLPVI
VELDPPTHLAVDGVIEGANELKKSGADAISLGENPLAILRADNLSLAHLIHEKLDIQTII
HLTCRDRNILGLQSQIMGAHLLGISGILAITGDPATSSDQPGTSGVFDVKSFGLIRMIEL
FNQGRNLAGKAMKARTNFSIGGAFSFRPSRPDVQIRRLERKAELGLKFVMTQPIFDSAEI
EEMMEAVSHLDLLILPGIFPLISARNADFLHNEVPGISIPAALRKKLWQYDKVEDQRKCA
LDYTRQLMDNVSDYVDGLYLISPLNKWEVTAELTREIRAANWQGSGRVGKFVKT
>A0A8E1C259|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium lucknowense F2|TrEMBL
MKLALERFPSDRNRSLIKKSRKTRNPERQSDSIGSKPALPGQDAPILDLVRSFSLEMTAK
DVASLADAAPMIPAGTPISVTYLPGETMPARVAAARTVKSLGFVPVPHISARRLPSKDDL
VEFLTVLDGEVGIDRAFVIAGDPPAPMGPYEDALAVIRSGLLDRAGIGTVGISGYPEGHP
DIGREKLDQAMKDKIAALAEQGKRVEIMTQFAFDADAILDWLARIRRDGVAAPVRIGLPG
PASVGKLIRFAARCGVGASARVMVKYGASISRLLSTAGPEHLIESLARQRDPAIHGEAML
HFYPFGALVDTARFIRSHYGDARE
>A0A1Y5SDG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius litorisediminis|TrEMBL
MITPNVSFEFFPPKSLEASFRLWDTVNTLAPLEPRFVSVTYGAGGTTRSLTRDAVGTLHN
ASGLNVAAHLTCIDASRQETLAIADEFAAAGVSEIVALRGDPPKGAANFEPHPEGFADSC
ELISALADTGKFTIRVGAYPEKHPEATNQAADIDWLKRKIDAGASEAITQFFFEADTFFR
FRDACVKAGIDAPIIPGVLPIENWQGARKFALACGANVPAWLDDLFGKAIRDNRHDLLAT
ALATELCSDLIEGGVKDLHFYTLNRPDLTRDVCHALGVTPKVELRDVA
>A0A1F9LPD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYA2_FULL_55_11|TrEMBL
MPSEESPVKLCDIYARPGLTFSVEFFPPKTEKGDKGLFKEIAVLKRLNLSFYSVTYGAGG
STREKTLDLVDRIHREYSMEVMCHLTVVGQSRDEVRSVLAQLKERNIENIIALGGDPPQG
VVEWTPNLDGFHHSVELVREAAAYRCFSIAVAGFPEVHPRSGSREEDLRYLKEKVDAGAD
VVITQMFFDNEDFCRYVEDAKKLGIRAPIVPGILPILSAPQVRRFTALCGAKIPPRLERM
LARVEDDEEGAVRMGIDYATKQCEGLLALGVPGIHFYSLNKSRSVKAIFANLNL
>A0A2I2MBM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum finnmarkense genomovar ulcerans|TrEMBL
MKVTKHIEKANGKTLFSFEIIPPKKGNNIQDLYQNIEPLMEFNPPFIDVTTSREEHLYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFSKEETEYLLVDCHYLGIEN
VMALRGDAMSHQRYFEVSKGGHQYATQLVAQIKNLNKGKYLHDVIEANHKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVKHAREMGITVPIIPGIK
PISVKRHLQLLPQVFKIDLPQNLITEIELCKNNQQVRELGIAWAIAQSQELLKSGVPVLH
YYSMGKSDNIKAISKALF
>A0A1V6YCQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium nalgiovense|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPVEKVDQALQAAYKSGCTNILALRGDPPREKEA
WEAAENGFCYAKDLVKYIREKYGNHFDIGVGGYPEGADDNTDVDQLIDHLKEKVDAGSSF
VVTQMFYDADNFIEWVKKCRAKGINVPIIPGIMPIQTYASFIRRSNWTKVKVPSEWMETL
EPVKNDDSAVRDIGKTLIANMCRQLIAAGIKHLHFYTMNLAQATQLVLKELELTPSEDSP
IQRALPWRPSLGLGRRSEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISDIFVNFLTGKLDRLPWSDSPITTEAHEIQEDLLE
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKNN
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCHDATSPSRQLIQHVMDDWYLVNIVDNDFHRSNAVFELFNGLEIKDLNVEVTGKPLTNG
HAEPNGVAAN
>A0A484GBR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Schmidhempelia bombi str. Bimp|TrEMBL
MKTYTHAQHHNLLNQYVIDIAENIDVSFEFFPPKTAEMETTLWQSVSRLATLKPKFVSVT
YGANSGTRDRTHDIIKAIKKRTGLIAAPHLTCIDASKDQLLEIAKDYWENGIRHIVALRG
DIPAGCPDPHIYAADLVALLKSVADFDISVAAYPEVHPQALSPQKDLDNLKRKVDAGANR
AITQFFFDIEKFLRFRDQCSKHNINIEIIPGILPVSNLQQLKRFANMTNVYIPPWLIKMF
TGLDDDVETRKAIGASVAIDMVKVLSGEGIRNFHFYTLNRADMSYTLCHTLGVRP
>A0A2S5YD71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. AY1B1|TrEMBL
MTRARFEIIPADDIGERAARAFPDPSAVTLTVTSLPKHGTGRTVDCAVALAGRGFRVVPH
LAARNVGGRGALERVLGRMGEAGIDEAFVISGDASSAAGTYSTSLELIRDAREISPGLAL
DIAGYPEGHPHLSDESIERHLRERAPFIRSVVTQMCFDVDAVVRYADRLRETGITADLWA
GVPGPVERSRLLALGARIGVGSSLGFLKRSTSVAGGLLRGRRFDPSAFVARLEAAAGDRL
AGLHVYTFNELDSLSAFG
>A0A1A5R4L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium loti|TrEMBL
MTPRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A2A6F6S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sanjuanii|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKNDEMEARLWDTVTRLEPLRPKFVSVTYGAGGSTR
ERTARTVKRILTETALTPAAHMTCVNAARHEVDAVVQEFADMGVKRFVALRGDPAEGVGA
AYQPHPDGYANGAELVGALKGIGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEVEAA
GSAAA
>A0A1V6G9V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium ADurb.Bin063|TrEMBL
MADKRFLISVEIRAERTRTLPDIVQGAAAVAEAGADLFDVPDNPGATVGRDAMVTAARLQ
SALDIPSICHLGVTQSNLMRLHSSLIGGWDLGLRGLLAVTGDAPSMGHLGNLAQRVTDVR
SSVELLRLLRGLREGRIINGEGLADPPDFCAGCAIARPIPPQIRWLKAKIDAGAEFVFSQ
PVFAVDDFRRLQDALAGLSIRFFPGVMPLVSRRNAQFLAGGRIPGIVVPREIAAGFEQYE
SPEDQRRYGLDQACLLSAAMAREAAGLYLIMPFGKSCYEDAARIVRHVRQAAGR
>A0A0H2N1E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. VPAP30|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELIQIADDYWANGIQSIVALRGD
IPPGGGKPDMYASDLVTLLKERHNFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A059ZWK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus caldus (strain ATCC 51756 / DSM 8584 / KU)|TrEMBL
MEFFPPKNPAGEAKLRETIGALQALRPDYASVTYGAAGSTQERTLATVAMLARDTELEAV
PHLTCIGSTEAGIRAILEHYRELGIRRIVALRGDLPPDREDPGFFHQALDLIAYIRAFGG
FQIYAAAYPEFHPRAVHARADLEYLQRKVEAGASGLITQYFYNPDAYLQLRDDLARRGVD
VPITVGVMPMTNYAQIANFSAQCGAEIPQFLRRRMESFADDPGAQAELAIEVASRQCRLL
LDQGAPGLHFYTLNQAEATLAIARNLGL
>A0A1G0A6Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon RBG_19FT_COMBO_69_17|TrEMBL
MSAPPAGWGRFEQALVSGRPVVTCEIGSADGADPEDVRKRARLVRDHVDAVNVPDNTGGM
VHASPLSSCAILAQEGIDPVMHMTVRDRNRLALQSDLLSAALLGVRNVLCLSGDHMVHGD
HPDTKPVYDIDSVQLVALAAHMTREGTYLSGRPIKPPPSLFPGAAANPFAPPYEFRPLRV
GKKVDAGARFIQTQIVFNVARFRTFMERVVDLGLHKRVPILAGVAPVRSVKAATFMRDGV
PGMDVPDAIVRRMEAAGDKKARREEEGIRICVEIIDELRGMPGLAGFHLMPIAWEAAVAT
ISKGAGLRPALGSSRPPLHASPVPELASA
>H3CC89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetraodon nigroviridis|TrEMBL
MVNQVQSVDSGWQSSKTDSSGASNSSGESSKESSRCSTPGLDGDHSNRLRDKMRRRIESG
DCWFSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKDKITGYLGKAKRLGLKNIMALRGDPVGADWEEEEDGFNYAI
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEQDLRHLKEKVDAGADFVITQLFFRAETF
LKFLEDCRRVGITCPVLPGIFPIQGYQSLRQLVKLSKLELPEEITSIIEPIKDNDAAIRN
YGIQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWSSRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELLSEESVFEVFTCYITAQTNRSGQKVLCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWA
KLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVLDDMLALLDAPAEALGQEAAP
>A0A1G1I0X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium RIFCSPHIGHO2_01_FULL_66_17|TrEMBL
MRRLREVIEGGEFAVTVECEPPKGTDVTTVLSRTKALLGRVHGINVTDNQAAVMRMSSLA
MCRLLYEQGHDPVFQITTRDRNRLALQSDLLGAHALGIRNVLCLRGDDPTVGDHKDAKPV
FDLDAAQLLAVVGGLNGGKDLAGNALKGSTDFFPAAAVSPEMVPPEPQLAGLEKKLNAGA
KFFQTQAVYNPDRFCAFMERARPLGARVLAGIVVLKSAKMAEYMNKNIPGISVPQHFIEE
LASADKEQALGVGIDIAVRIIKQVREACHGVHIMAVGADQAIPQILDRAGLG
>N9HQI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii NIPH 478|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAADLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGASSLHFYTMNTTDPTRQLVTDLGLA
>A0A4P6FNB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingosinicella sp. BN140058|TrEMBL
MSTLAPGIASWRKPLFEDVAGDIDVSFEFFPPKTEKMEQTLWESVKTLEPLAPRFVSVTY
GAGGSTRERTHNTVARIARETTLAAAAHLTCVEASREEIDEVARAYWEAGVRHIVALRGD
PPEAGKKFAPHPNGYAGAADLVQGLKRIAPFEISVAAYPEMHPDAVSRQADIDNLKRKID
AGADRAITQFFFSPDCFFRFRDEAAAAGIDAEIVPGILPVSNVAQTRKFAAMCGAGIPPW
MDRLFEGLDNLPAARQLVAATVAAELCGQLYAGGVRHFHFYTLNRAELAYAISHLLGLRP
TPDQQEQAA
>A0A1Y5SFW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanibacterium hippocampi|TrEMBL
MINLAGRPLRDMEDRLSLARANARLRVSFEFFPPATTTMRDSLWRAITRLAPMRPTFVSV
TYGAGGSTRERTHETVHRIRRETDLEPAAHLTCVDTSAGEIRDIAARYWDEGIRHIVALR
GDPPEGGASFRRHPDGYGSAVELVAGLKKVADFEISVAAYPEIHPEARSSLADIDFLKAK
IDVGASRAITQFFFDPDCYFRFLDRALARGIEVPIVPGILPVSNFQKVAEFAGRCGASVP
AWLAHLFEGLDGDPATRQLVAAMVAAEQIRRLQAGGISDFHFYTLNRADLVYAICHALGL
RTATQEDDVREAC
>A0A117REM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces bungoensis|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFYAPKTPQGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTTTVRETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLAYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDTDVRHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVLPVTSVKMLERVPKLSTALF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A0L0BKA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. RIT-PI-e|TrEMBL
MSPSAYPALSFELYPPRNSEAQESLWTTVQRLEETRPDFVSVTYGAAGSNREAAIGLLRH
LLTDTTLKPLAHLTCVGSTRVELVEIVERLLDGGVRGLLALRGDLPEGRTEPSGEIRYAD
EFVRLIREVESGRTAQLAAGKVSVGVAAYAMRHPESESLEQDVAVLLAKEAAGADFAITQ
IFFRRSDYAGLLTRARDAGVTIPIIPGLIPFTSPRRLTKLCDLAGIEPDRDLMARLEEAE
DDDARRSLGVGATVELGRAVLDEGAPGIHLYTFNQPTAALDVLEALDLARPPEAGSAVTL
>A0A1H4U2V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 2314.4|TrEMBL
MRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTADLRNIIGQYAGAGIRNMLALRGDPPGDPMGEWVKHP
DGVAYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVDKCRAGADFAITQMFF
YPEDYFRLRDRVTAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQQS
>A0A1Y1RXS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marispirochaeta aestuarii|TrEMBL
MSLPGNQRVNHPSISFEFFPPKTEKGFAALKRRIVDDFVPLKPSYVSITYGAGGSTRELT
RETTLAINTETRLPVVSHLTCVGSSRNDIAQVLDEYQEAGISNILALRGDPPKGSDEKTG
DFAWAAELVAFVKKGWPGMNIGVAGFPEGHPATPNRLVEMDHLKAKVDAGADYICTQLFF
DNRDFFDFTERCRIAGINVPVIAGIMPVVSRANLQRMAELSPGTRFPAGLLKSIARTRSD
EQVERVGIHWATQQVMELLAADVAGIHLYTLNQSRAVLDIYRALGIEDSRQL
>A0A847WC62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Papillibacter sp|TrEMBL
MKVTDIMKSRMAFSFEVFPPKKDMPMEPLLNTLDKLYEFKPDFISCTYGAGGTNAGRNLE
ICSAIKLSGRSVPVTHFTCIGNTKEGVRQQLNAYLDNGIDHILALRGDLPQGWEGTGGDF
SYANELIAFIRKEYGSRFTVAMAGAPEKHIQANSFKEDITHLKMKQDAGADFIMTQLCFD
VEAFARWRDMIRSAGISLPLDVGLMPVLNKDATIRMALSMNGCSIPRELAELISCFY
>A0A847WHQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epulopiscium sp|TrEMBL
MTNKLQIYLKDNIIITDGAMGTYYAQLTGQNSTLSEWGNKYEPVLIEKIHREYIEAGAKL
IRTNTFSVNQDTMKISSIEVKEMIEKGYEIAKKAVGRKDIFIAASIGPIPEVTLDGNQKT
VEELIQEYKEIIDTFLSVGATIFLFETFSHTEPLDILVKYIKAKNPAIFIWTQFAVTITG
YTRKGWNIKKIITEIKKITGIDAYGFNCGVGPTHLHQFIRQLNIEQEFVSALPNAGYPEV
IHERTIYTQNPNYFANRMKEIKNLGVKIIGGCCGTTPLHIQNVAEKIQSIDGMNQPKDLK
AIKETSIETSIVTNKFKEKLEKGKFVIAVELDPPFGTKVNKIIQGAAELKKAGVDVITVA
DSPLGRPRMDSILVATKITREVGIETIPHLCCRDKNIIGLKGQILGAYIEGIRNLLIVTG
DPIPSAERNEIKSVFNLNSFQLLNLISQMNEEHFIREPYHLGGAFNLNVLKKDQERERME
RKMKEGASFFMTQPIFDDEIIEYLKKIQDRKKGKILGGIMPLVSYRNAQFLDNEIPGIQI
PENIINRFHDDMTREEAENLGIEIAVEMGKKLRPWVDGFYFITPFQRVSMIRKIIEQL
>A0A8G7KL79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKASASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A7V2NCQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
LKSAGMANFMNKNVPGIMVPQDLIDEMKAAGKEKALDTGLNIAARHIRQLKEEKICDGVH
IMAIGMEDKVPEIMERAGLL
>A0A0S7XF35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Latescibacteria bacterium DG_63|TrEMBL
MRQNLVERLRSRIVLIADGAMGTVLYARGAPKGHCYDELNLSNPSMIKAVHAEYAAAGAE
LIETNTFGANRFVLSTYYDLGAKTFEINLAGARIAREACPNCYIAGSVGPASRPLDTTEP
IGREEMAGIYVEQISALVEGGVDLIVLETMADLDEAKIALEQAVKVGKVPVVVQMSFVDE
GRTITGVSPSQAVVELADMGALVVGANCGNGPQATLEAIRKMTGRRDVFLSAMPNAGLAS
YTGGKFSYPHNPDYFASCAEEFLKLGVAIVGGCCGTTPEHIATVSSRILGKKVVVPKRGA
KKLEKAVRIGSPPVVSTPLKEMVSRKFTITVELSPPKGTELTDDLSSAGELKEVGVDAVS
ISESPMARIRMSPVALGHRIKTELGMDVILHFTCRDRNILGLQADLLSVYALGMVNILAL
TGDPPSVGDYPFATGVYEVNSRGLVEIVNKLNSGVDYLGNRLSSATAFWIGVAASPASED
PENEIKRLGEKMKAGAQFVVTQPVFDVEGLSDFIKRANLREKPVFAGLMPLVSSRQAEFL
HHEVPGITVPESMRKAMRTAGERKARKMGVTIAADLLNQLVEVVSGVCVMVPLRRYSVAA
EVITEADLSEAARSAP
>A0A2W6AZF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MLVQQAFSPPALPARHRRWPSSMCGRASFHPSSSIEPLLRSASPSRPRGRRSRRRARPHD
RDDHRRPCLGHRARGRGIRGYDSVRAPIPRATSHRAGAAGWKAGARLTGHRAPDGDRRTA
RARTDFARRIVVCDGAMGTMLHTAGVPLDRSLSELNLSRPALVADLHKAYVAAGARLLQT
NTFDANRLRLGQRGLEENVAEINIAGARLARQAAETASEHPDGPVLVAGSVGPALSAPAL
TRVPAETRAATLREQIDALADWVDVLVLETFGDLESLVQAVEVALSTCDLPVIAQLTFGD
DGCTLRGEDPATAASVLGGYDVAAIGANCTVGPAALHDVIAEFAAATSLPVSVQPNAGVP
RRLGGQVRYARNASYFGEAAPGFVASGATLIGGCCGTTPAHVRAIASALDGMGPAVRIPP
SRSRGLRLVPPAPAEHPARDLAGWPPPGRFVVVPGLPTPRDQHVDTFVELAAALRDAGAD
RIAVTEPEPPRTSVSPVAAGVVARERVGIEVMFSIEAVDRGLPALQADLLGAHALGLRTV
ICRTGSARVAGDYPDAGMQTTVDSLGLISLLAGLNVGVDCHGVAIRDATRFVVGAGIRTA
ALDVGTEVDRALAKVRAGAHFLVTDVVYDAHRAGRMLSLLRDRGVVVPVLVSIAPHADQR
LLRAQSRETPGVVSAPSVVAGAQTPAAATKRALEMVAVLGGLAAGVVVRLSYERAAEAVG
LVRSLVAARDTA
>A0A1Y6K9Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevefilum fermentans|TrEMBL
MCENVNKFKNRLISSDRPIVTDGAMGTLLHDRGVKIDACFDALNLTQPAAVAEIHLEYIQ
AGAEIIKTNTFGANRIKLERHGLIDRVEEINVAAVNLAQRVIMASFRDVMIAGDVGPLGM
PLAPFGRIQPEEAFEIYVEQISALVKAGVDLILIETMVDLYAVKAAVNAARYVDPDIPVI
ASMTFTLDRRTLLGNTPQEVAQRMDEYGVDVIGVNCSGGPAQLLHILRLMKSAVPSGRFS
VMPNAGLPEKVGGRIMYSAGPDYFHDYALSFWRAGADVVGGCCGTTPAHIAMMTKAVANT
SKEDLVNGVSVLESTVEVVQEPAEDRSHLAQKLDAGKFVIAVEMDPPRGLSTQKLLAGAS
LLADAGADVINVADSPMARMRMSAWAVCQLIQSKFDIETTLHFPTRGRNLLRVQGDLLAA
HALNIRNVFVIMGDPTAIGDYPDANDAYDLVPTGLIRLIKEKFNIGKDHSGGLIGQPTSF
FIGAAMNLTPNNPAQEIRVLKKKIDAGVDFFMTQPVFDVQKAGAFFHRCQQEIEWKNIPV
LAGVLPLVTDRHARFLHHEVPGIQIPASIQQRMSAAGEASVQEGVRIAVELIDELRSVYQ
GVYIMPAFNRFDMVAEIIDKIRGEKVT
>A0A0X7A7Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. D14|TrEMBL
MLRSETARQNGDIRLSFEFFPPKNPEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLATAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYK
PHPEGYENAAALVKGLREIADFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMDRVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGINEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A521QZN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reyranella sp|TrEMBL
MSPDTGPLSTSTHAAEFPARAPQRLKVSFEFSPPRTEAAERTLWETVSRLTPLHPTFFSV
TYGAGGSTRQRTHETVARLKSETGIDAAAHLTCVAATQGEIDDVARAYWDAGIRHIVALR
GDPPGGMGGKYSVHPGGYENAAALVAGLKKIGPFQISVAGYPEKHPDSADAKADLENLKR
KVDAGADRCITQFFFEADDFLRFRDSAAAAGVHVPVVPGIMPVSNFQGITKMAGLCGSKV
PAWLANLFDGLDDDVETRRLIAATVAGDLCRRLQSEGVEQFHFYTLNRADLTFAICHLLG
VRPR
>A0A060HGA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylella fastidiosa MUL0034|TrEMBL
MIPISFEFYPPKNDDQRAQLDRTANRLRAFAPEYVSCTFGAGGSTLSYTSETVRHLSQHH
GFDAAPHLSCVGGSRQEIRELLKLYRAIGCQRIVALRGDLPSGMGHPGDLRYAADLITFI
RAEHGDHFHLEIGAYPETHPQASNTLNDLHYFKAKVDAGADAAITQYFYNPDAYFHFVDA
VQRLGVTIPIVAGVMPISNFDQLRHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVV
TALCERLIAGGAPGLHFYTLNLAKPSTQVLQRLGY
>A0A5C8J6T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ottowia sp. GY511|TrEMBL
MTTSSSLSLEFFPPKTPEGAEKLRAVRSKLYALAPEFCSVTFGAGGSTQEGTLDTVREIL
AEGHAGVPHLSCIGQTHDSIRQRLARYREAGVRRIVALRGDLPSGYGLGGEFRYASDLVA
FIRAETGDHFQLAVAAYPEMHPQARSPQTDLDAFIAKVQAGADVGITQYFFNADGYFRLV
DELRRRGIDTPVVPGIMPITNSTQLLRFSDACGAEVPRWIRQRLESFGDDSAAIKDFGAD
VVTALCQRLQAGGAPSLHFYTLNQSVGTLEVLRRLGVA
>A0A1X1IVI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. dentisani|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLAKEKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFRYATD
LIGFIKEQASHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A4Y1X0P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes dispar|TrEMBL
MNVPEIINEAIAAGRTRFAFELLPPLKGDGMQKIFAAIDPLMPFDPAYINITYHREGIKE
TALPDGGIEWHVVRRRPGTVGISAAIQHRYGVEVVPHLICGGLSKYDIEDTLIDMDFLGL
HNVLALRGDRSQNERRFMPHPQGHAHAADLVRQIAAMNRGEFVDGEVEECHHSKFSIGVA
GYPEVHFEARDVTSDIRHLREKIDAGAEYVITQMFFDNSRYFDFVRRCREAGIAVPIIPG
LKPISTLRHLEVLPETFAVTLPEELVREAKAHPEHVREVGVEWTVAQSRELMAAGVPVLH
YYTMSRTTNIQQIVKALF
>A0A1H1AI98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora saharensis|TrEMBL
MSTNARQQLQHHLRNARYEVLPLRGTLEQVQGLPPGTTVTVTSSPSKGTEATLDLAARLR
GSGMHVVPHLAARLVRDSAHLDELLSRIEALGLTEVFVIAGDADNPAGRFTDALSLLRGM
EEIGNRPHRVGITGYPEPHSFISDQMTIQATDEKARYADYIVSQICYDPNTIASWVKTMR
ARGVTLPVYIGAPGSIDPSKLLRISMKIGLGQSMRFLRKQHGVVGKLLTRYTPENLFDEL
SPYLVNPDYNIAGCHLFTFNEIAKTRQWAMETADRLQEVPA
>A0A0E3ZWJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma radiotolerans|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPIKGDNLKSLLDNIEPLMEFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFSREETEDFLIDLHYLGID
NALVLRGDPAKPFTTFKAKENGYMYASELVEQVANMNKGIYLHEEDTALAPSSFCIGVAA
YPEKHFEAADHDTDFQYLKQKIDKGADYIVTQMFFDNKKFIDFVDRCRKEGINVPIIPGL
KPLSTRRQLQVLPKLFHLELPADLVRAVEACENDQQARQVGIEWCIQQCRELIAYGAPVM
HFYTMGKSDNIMKVAQEIF
>A0A2W6CI96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MARTVRDCLATGRPTISFEFMPPKTPEDERRIWQTIRELEPLQPSFVSVTYGAGGSTRDN
TISVTERIASDTTLLPVAHLTAVNHSIAELRAIIGRFADAGIVNMLALRGDPPGAVEGEW
KRHPQGVGYASDLVSLLAAHGNFCIGVAAFPYKHPRSPSVESDTELFVAKCRAGADYAIT
QMFFDGEDYLRLRDRVAAAGCDVPIIPGLMAVTTIATIERSEQLSGAPFPAALAKRFEAV
ADDPKAVRALGIAEASALAQRLLDEGVPGLHFITMNYSKATREISANLALATLA
>A0A6I7PBK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MNQHHLTSAYHVEILPPKQETEKLYEDLDRFAQKYKRVMESGYCACITDNAMGNLAFQGT
EMIEELHLPALENQVMIHLNTFHTKDDLHRILDACRNSGIRQLLVITGDGSDRLPRLTPS
DVGADGVEAVTSVELLRYIDRAYPGDFDLGVAFNPYEPEDHEFAKLDRKIAAGASFAITQ
PVIERHPVVDRLLAEYPDFPVVVEAWMSKKLSLLSEAVGYEIPQDAAYDPIENLKTLHRN
YPRCEVYLSILGFKTQYDLLQHVRN
>Q65LG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)|TrEMBL
MGFLEDIKNKTLIADGAMGTLLYSYGIDRCFEELNISKPEEIRRVHEAYVQAGADIIQTN
TYGANFIKLSRYGLEDETKQINEKAVRLARAAAGSAYVLGTLGGIRTFNKNSYSLEDIKR
SFREQLYLLLNEQPDGLLLETYYDLEEAREVLKIARKETELPIILNVSMHEEGVLQDGTP
LADGLKQLASLGADVVGINCRLGPYHMIRALEEVPLLEDAYLSVYPNSSLPSLVEGRLVY
ETDDEYFRESAEEFRNQGARIIGGCCGTTPNHIRAMAEAVKGLPPVTEKRVKIRKKAALA
VQNERTEPALDDLAKQKRSIIVELDPPKQLNFEKFLHAAEELKSAGIDALTLADNSLATP
RISNVACGALLKQRLDMRSLIHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRLE
KKIACGADYFISQPVYSEEQLIKIHKETRHLETPIYIGVMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGNDKQKQAEEGLAIARSLLDAACDLFNGIYLITPFLRSDLTAELTAYIH
QKEKEKTNV
>A0A8E0ED93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus M1015|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A4V3QZI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas gei|TrEMBL
MSACRSKDRSSPTITVTEAVTVQSALTAPLSAAEPATVRERIAGLAREASYEVAARDARG
IDAAIARLSPGTLVSVTWLPLDDDEARVLASRRLREAGFEPVPHIAARMVTSDDHLQRLL
RRLCDEAGVRQLLVISGDVKQASGPFEDSAALIASAAFAQPALSRIWLGGYPEGHPKVDH
ATLNATLDAKIAAVRALGMTPGVITQFCFDADPILRWLLDFRARHDVPVRIGLAGPAGIR
TLLRFAAICGVGASARSLVTRSASIARLLVDTTPDPIIRDLAETAAYHDLQPMGFHLFPF
GGLDRTARWMGSVAAGGFELRASASGFQVTE
>A0A1Y2DJX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucosporidium creatinivorum|TrEMBL
DPPRGEEYWVAASDEFQHATDLVKYIREHHGDDFCIGVAGYPEGHADSEDKQMDIEYLYH
KQQAGADFVVTQLFYDVETFMAWYQACRDRGITIPILPGIMPIQNYQSFRRMTNLCKSFL
PPQLVKELEEIQHDDAAVKEYGVNLAVEMMRDLRKGGINGFHLCTLNLEKSVTKVLEKLE
WVQPGQNKATLPTNGGPLPKAVNSLRPSTPGGTPGGSFNGQTVASPDIARKDSPTSWDEF
PNGRFGDARSPAYGDLDGYGVGLKLPPAEALRQWGRPTTLSDVSTIFSSYLSGKLPSNPW
SEEPLRAETTSISASLIRLNDERHWWTVGSQPAVDGAPSAHPVHGFGPKGGYVYQKAFVE
FFLSEEELDEFEKRSEEEEKGRRERGEGEEGLIKWFAGNRRGDSRSNMGKGDVNAVTWGV
FGGKEIVTTTLIEEMSFKAWNEEAFAIWLEWSHLYPAGSDSRKFIRDLADTRWLVSVAHH
DYKDEMGLWNWLLEQGKK
>A0A2A2IMR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera sp. ASD88|TrEMBL
MRTNELFAKKTVFSFEVFPPKPDTPIETIYAALDELSQLYPDFISVTCGASGSGSGGNRT
VEVASAIKHTYGCETAAHMPCIYLTEDDALRTLDELKKAGIENILALRGDETPGRERAHV
FEHASDLVAFIKRNAPEFNVIGACYPEGHTEAQTMAADIRNLKTKVDAGASELISQLFFD
NATFYRFLERCEIAGISVPIEAGIMPVTNKKQIERMVSLCGATLPVKFQRAIAKYGDNAE
AMRDIGIAYAIDQIADLLANGVDGIHVYTMNNPYIAKKITEAVKNLL
>A0A327IP28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. SL1|TrEMBL
MSAQEHPLGISFEFFPPNTEAGRDKLMQTRDALATRGPRFFSVTYGAGGSTQHRTTDTVR
MVRESGFTTAPHLSCIGSEKAALRDLLAQYREEGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFNIAVAAYPETHPQAPNADRDVENFARKMKAGANLAITQYFFNADAYF
RFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSESIAAF
GEDVISRLSQRLLDGGAPGLHFYTLNQAEPSLRVVDNICG
>A0A157Q6R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella ansorpii|TrEMBL
MARSPATASPLIQPDQPRPASRITEDYSFEASTKDLPALAAAAPRILPASTVSIPYLASE
DDDVRLAAARAVRGLGFEPMPHLSARRIASLGQLRSFVERAADEARVERCLVIAGDPSTP
IGPFSDSASLIETGVFERAGITVIGVGGHPEGHSAMSLAEQWEVLARKCRSIEMRGMAPL
IFTQFVFDADIVLRWLEALRERGIEHPVRVGVPGPASLAVLARYAALCGVSACASMWSKY
GISIGKLLGTAGPDLFVDRLAAGLTPAHGKVSLHFFPFGGIAQSVKWIEQYRARAEPPRF
TNTSMA
>A0A374U7W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. TF07-1|TrEMBL
MRVDEVFKQAASQGTTPISFEMFPPKGELTLDTAREVADNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>K8BC16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter dublinensis 1210|TrEMBL
MEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFAGLDDDAETRKLVGANIAMDMVKIL
SREGVKDFHFYTLNRAEMSYAICHTLGVRPAVELKTA
>A0A1Y3AKT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euroglyphus maynei|TrEMBL
MHENLKKCHVVSESSPGFVPLCRKLIERSQSPEVSFFSIELFPPKTWKALDNLVPLLNNF
RQLGCLFSTVTWHSNVNQMENLNDILSMQVVEIALNYCWLDTMIHLTCVGMTSDKMLAIL
ERLKQIGIRNILALRGDLTESTDNKVEEFKHASDLVRFIRHHYGDYFTIAVAGYPIKHPE
SMNKQHDRENLKIKVDAGADFIITQLFFESDVYIGFVNECRAIGIEVPILPGIMPIQNYD
SLAKIARLSQLDIPNQIIQDLEPIRNNDEAVRNYGIEWTIRLCRELMKSGLTPGLHFYTL
NRQHATTTIVKALQIGYSFCYKPLPWQQPVNHRRCSENVRPIFWATRPESYVQRTNTWDE
FPNGRWGRVHSPAFGSLNDYHLFVALDSITPKNRKRYVAMWGKQLLNEQDVWQIFEAYVA
GTNNRFGHKVESLPWNDDVLAPETNVIRARLSRVNRHGILTINSQPNVNGISSSDSVHGW
GSPNGYVYQKAYVEFFISGDRIDRLLEILAQYPLVNYQITNNK
>A0A4V4HQ62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium rosettiformans W3|TrEMBL
MTKTERPITRTSELKISFEFFPPKSPDMEAQLWQTVEALQPYQPDFVSVTYGAGGTTREP
TLSTVKRLIDDTPLATASHLTCVGATRDEVRAVVEEFEAAGVRHFVALRGDPQGGVGTRY
APHPGGYVNAADLVSGLRAMGDFEISVSAYPERHPESENDTVDLDMLKQKVDAGATRALT
QFFFDNDVYERYMERVQAAGINIPIVPGIMPIQNLTQLKRFASMCGASIPSFLDARFEGS
EGDAQARAAIAADLAAEQIADLSRRGVQEFHIYTMNRAPLTIATLDRLGVSPKAGRVSGA
AA
>A0A1G1DDN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium RIFCSPLOWO2_01_FULL_39_10|TrEMBL
MGLRELFDKKEFVVTTEIPPPKGVNAASSLDIAKKILGRVDGINVTDNQRGIMRMCSLAF
SHLLKEIGHNPIMQVCTRDRNRLALQSDILGAGALGIENICIMTGDHPKLGDHPDAKPVF
DLDSIQLIKVIKEMETGVCMSGKRLESFAKFFVGGVANPFFEPFELELIKIKKKIDAGAE
FFQTQPFFDRESLEKFLEDVRGLNTKFLIGISPIKSIKMITFLNEKVLTKKIPENISKRV
EAAENQTEEGIRIAAEFIRDIKGMVKSIHIMPIGIESYLPYLLDEAGL
>A0A1I0L124|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stigmatella erecta|TrEMBL
MKIRNRLNPSNPCFSFEFFPPKTDEGTENLLKTVEELAPLEPGFVSVTYGAGGSTRDKTL
GLVTRIKQTTGIEAMAHLTCVGHTRDELREVLQQLETAKLDNVLVLRGDPPRGQTAFEPT
PGGFRYASELVEFIREEDFNFCVGGACYPEGHVETESRDDDLQHLKAKVDAGLDFIITQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNVEQVQRFTRMCGATVPMRLGLQLDRVKD
QPDAVVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMILGALRSRS
>A0A4P6ESF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylanimonas allomyrinae|TrEMBL
MPPRRPDAAPRFWETARRLVAVHPDFVSVTYGAGGGDRATAHRVVATLLAGTPVLPIAHL
TCVGASREDVSEVIDDFLDAGVRAFLALRGDPPRDQPDWRPPADGVHSSIELVRLLREVE
AARSAADPSSALRGAAHPLSIAVATFPDGNPAAGTTRAQEVRRLLEKQQAGASFAITQLF
YDADSYTGFVAEARAAGVTIPILAGLLPTTEPARLRRVEELTGVVAPSRLLASLEALDDP
EARHAYGIARSVEVAQAVLDAGAPGLHVYTFNKHRPALDLLDGVGLLRREDPDLLAAGAP
GVAAHDSRPAVGGLAPLGAAYRADASAPAGG
>D3HXT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella buccae D17|TrEMBL
MNVSELLHKSKGERHFSFEVLPPLKGNGTEALFNTIDKLKDFGPQYINITTHHSEFVYQE
MDNGLLKRLSIRRRPGTVAIAAALQNRYRIPVIPHVICSGVSAEDIEYELLDLQFLGISN
LLLLRGDKAKEDRSFVPAKGGHTHTTDLIRQVVRFNEGFFNDGTPIKHPGRHFDFGVACY
PEKHEEAPNLEQDMLHLKEKQELGAQYAVTQLFYDNEKFFRFVDRARAMGITLPIIPGIK
PLAKLSQLTMVPKTFHCDIPQELAAEALKCKTDEDAKALGVEWTVAQVKDLQSRGVNNVH
FYTVSAVDSVKEAVKKLF
>R6PFI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:306|TrEMBL
MNLKEIYTTKKQEPVISYEVFPPKDDIDATKLEKLFDELKKLLVFNPSLISVTYGAGGSN
QNESVEIIKRIKQELNVSPMPHFTCVSTSTENIKNYLKTLKSLDVKNILALRGDMPENQK
IYNDFKYASELVEYLKKESSLSIAVAGYPEGHKECESIEKDIQYLKQKVDNGADVIFTQL
FFNNSHFISFVEKCEKQNITVPIIPGILPVTNYKTLEKMSTLCNAEVPAKMAQVLEKHKD
DKDYIKQYGIEYASLQCRELLETGIKGLHFYTLNKAYATSEILKNILYTRTN
>A0A8D5FW87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomarina profundi|TrEMBL
MELKTNSRLEKILKSGHLAVTSECGPPRSSDPAGIIKKGELIKDHVDSINITDNQTSVTR
LCSLAACVHLKQQGLDPVLQMVVRDRNRIALQSDILGAASFGINNMLCLSGDHQSFGDHP
AAQNVFDIDSMQLIQTARHMRDEGKFLGGDAIKVPPNLFVGAAANPFADPFKIRVPRLAK
KIAAGAEFIQTQCVYNLDKFEEWMKGVCDRGLHEKVFILPGITPMRSVGMAKYLRRAVPG
MDVPEELVKRLSGVPKDKQADEGITIAVEAMQRLKEVKGVAGFHVMAIEWEEKVPEMVER
AGLYPRPEID
>A0A7Z9WTF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piscirickettsiaceae bacterium|TrEMBL
MQSQQQYPQPLSLEFFPPRTDAGFEKLKQTIATLGEAIQPQYISVTYGAGGTTQARTVET
VEYVQTQTPYDAAPHLTCIGQTRQSVLELLHTYDQLGVARIVALRGDLPSGMLDPGEFKY
ASDLIRFIREETGTRFTLEVAAYPETHPQAKNCDEGIKWFQYKVEQGADEAITQYFYNVD
SYLYFVESCEAAGIKLPIVPGIMPITNYEQLIRFSNMCGAEVPRWLRCRLESFDDRGDRE
GLLAFGRDFVTTLCQRLLDAGAPGLHFYTMNQVEPTLSIAQALTIHRPA
>U4LTD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyronema omphalodes (strain CBS 100304)|TrEMBL
MVHVSAKIAESNRLKKPTFSFEFYPPKTGQGVQNLYDRMDKMHGLGPQFIDITWNAGGRL
SNLTCEMVKVAQSVYGLETCMHLTCTGMPKEKVDEALREAYKAGCTNILALRGDPPREDE
PWTADPNGFRYAKDLVKHIRNTYGDYFDICVAGYPEGCEEGTPEDELLQHLKEKVEAGAT
FIITQMFYDVDIFLSWVQKCRDVGITVPIIPGIMPIHTYDAFVRRAKWTKCHVPPRWYEL
LEPVKNDDVAVREIGRDLLVEMCQKILDAGIYQLHFYTMNLATATRMVLEGLNLIPTVDQ
VHPPLPFRPSLGFGRKDENVRPIFWKHRKASYVQRTENWDEFPNGRWGDARSPAFGGVDS
YGIGLRGSNVANRKLYGEPKSIREIANTFVRYVNGQISSLPWSESSITAEVDVIKDELIK
LNERGFLTINSQPSVNGIKSSDPVYGWGPRNGYVYQKSYLELFVSPEVLSDLITNIERDS
EMTYYVVDKAGNLSTNAPDCPNAVTWGVYPGKEIIQPTIVETVSFLAWKDEAYRLGEDWA
RCYETTSASRHLLQSIMDSWYLVNIVDNDFHRSGAIFRLFDNLEVKNIDETLEISEHLKD
LAINGDAKPAEAVVAN
>A0A6S4UY38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas veronii|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPEMYATDLVALLKAEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLENDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQP
>A0A2J6SHI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyaloscypha bicolor E|TrEMBL
MHIKDMLAEAEKSGRPTFSFEFFPPKTAQGVQNLYDRMDKMHGLGPSFIDITWGAGGQLA
DLTCEMVSVAQSQCGLETCMHLTCTDMGKDAVNSALKNAYSAGCTNILALRGDPPREKEK
WEATEGGFLYAKELVTHIRQTYGNHFDIGVAGYPEGCDDQDDPELLLDHLKEKVDAGATF
IVTQMFYDVDNFVDWVSKVRAKGITIPIVPGIMPINTYASFLRRCNHMNATIPPKWATAL
EQVKNDDAAVRSLGTGLVAGMCRKILASGIHHLHFYTMNLAQATRMVLDELSLTPSDQRP
LKQALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDT
YGIGLKGTNEQNRKLWGEPRSIKDIADIFVKYLEKGVDSLPWSEAPITSEADAIKEDLIR
LNKRGFLTINSQPAIDGVKSSDPVYGWGPNNGYVYQKAYLELLVSPTLIDELIARIEQNP
DLTYYAVKKVGNVRTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCYSSLSPSRQLIENIMETWHLVNIVHNDFHQARGLFPLFDDLEVADLDKPVEVGETNG
VGAKPNGVENIPLSNGSVKH
>A0A0P7B8L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neonectria ditissima|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGTT
SQKSLELAELCQRELGLTTCLHLTCTNMSRKLVDKALEDAKALGIRNILALRGDPPRRDE
YRDPEDSEDDGGEDFNWAVDLVKYIRKNHGDYFCIGVAAYPEGHADESHPLGQSLDHDLP
FLVDKIKAGADFIMTQLFFDIKAYDHFEETLRSHPSGAFKTLPIIPGLMPIQSYQMIKRT
TKLSHAKVPDDVLGRLNAVKGDDERVKMVGVDIVSELVEQVKEVKSRSPGPKGFHFYTLN
LEKAVSFILERTNLIPDPPQDEEAVVADDAILIPALQVNGSANLHPSSHSRSRASRRHSS
VGSDPHNRVIVGDRAVPHPEWEATAQEAGIRAEAINTRANTLAISEGEGVLGREATWDDF
PNGRFGDARSPAYGEIDGYGVSLHMSVTQAVRLWGHPKTRQDINDLFVKHIKGELSAIPW
SEEELLPESSTIQPHLLQLNTKGWWTVASQPAVNGLRSSDSTFGWGPSHGFVFQKSFVEC
FIPTTEWTVLKAKLTSPELRDSVCFYAGNARGDFVTSNSNGGLGSTDIAGGASTNAVTWG
VFPGKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSDTEKLLSGIKDEYWLVNLIH
HDFVEKDALWKVLTS
>A0A0B5BPB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium adolescentis|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVDEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
CIREKRPDLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCESRVPEKLAVLLDKWGSDTALLKEAGIAY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>H8GYK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus gobiensis (strain DSM 21396 / JCM 16679 / CGMCC 1.7299 / I-0)|TrEMBL
MTRISLELVPRSRSGLRAELDTVREHFPGVDTVNVPDLTRFSTRSWEGCAFARPHLRAIP
HIRAIDLNPKEPLPMSGLLLAHEIDEVLIVTGDAPSDMNRRVYNVDAEAAIRRFRRELPH
VRVYAGLDPYRQSFARERDYLERKLEAGAVGFFSQPFFDLRLMDTYADLLPEGAEMWWGV
TNVTTEGSANYWASRNNAVFPRSFDLSLEWNRKLAGDALHFARDRGQHVYFQPIRTDLRE
YLEGIL
>A0A0R2FWS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weissella halotolerans DSM 20190|TrEMBL
MQAISDLIVKLKRPSRSIELTQPKAMETQRQLLESLADIKDSLDFVSLSNHKSQGLTLVE
RISFAQQIQSRYDIPVLEHVTVAGIPKEKLLAHLAAYQTAGIQNILVVRGDDPLTDRTMK
ESAQLLTAIAANGGFNLAATLDIKHLIQQPAETLTNSLAKQAAGASFFITQPIQSLTQWQ
SGQRILRKQALQLPLVAGIMPPGASKGLKKDPTRGKLSKQSIQECQLLVQDLAREGLLGW
HIFSPQLLSGETKSLIASICQEN
>A0A1Q7M0Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium 13_1_40CM_3_69_14|TrEMBL
MRITDMLRFAAERGEPVFSFEFFPPRNDAGVAALFETLRALRPLAPSFVSVTWGAGGSSR
GRTLEMVTRIKRETEIEAMAHLTCVGASRKELEEQLAVICDAGITNVLALRGDPPRGQRE
FIVHPEGLAHATDLVQLAREVADKRGVSLCIGGACYPEGHPETRDLAKDLRHCKQKVEAG
ADFLITQLFFDNRRYFEFLGRARAAGIDVPILPGIMPITNVDQIERFTALCGAHIPAGLS
AALRARRDDPDAALQLGVAYAALQCAYLLRGGAPGAHFYTLNRSTATRAILAALRAQEPW
RDA
>A0A522XF71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phormidium sp. SL48-SHIP|TrEMBL
MSRLRTAIHAGEFLITAEVAPPKGGDPSHMLKMATCLKRRVHAVNITDGSRAVLRMSSLA
ASALLVQYGIEPVFQVACRDRNRIALQADLMGAYALGIRNVLALTGDPVKAGDHERAKSV
FDLESVRLLQTLHKLNQGIDFNDRPLSDGKLDLFGGAAVDPQLASWSGLQRRFERKIAAG
AQFFQSQLISDFDRLDKFMTQIAAEYDKPILAGIFLLKSAKNAKFINKYVPGVHISDETI
DRLDEAADPLREGMAIAAEQIKQARCLCQGVHLMAIRTEHLIPEILDMAGIPPISRPSSL
QR
>A0A0C3F4U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piloderma croceum (strain F 1598)|TrEMBL
MKLSDKIKSCDSSRPFYTFEFFPPRTDQGFENLISRIERLSALKPIAISITWGAGGSTKD
RSLALAGLTQAEYGIDTVLHLTCTNMVKGMVDDALRAAKSRGIETILALRGDPPRGEEEW
IPVDPNFTHGVDLVSYIRSSREFSSYFCIGVAGYPDGHDKDTAEDAELNYLKAKVDAGAD
FIMTQLFYDVDGFLQWVKKVRAKGINVPIIPGIMPIQTYSSFLRLIKLCGTKVPPAISAA
LEPIRHDDQKVKDYGVSLAVNMIRRITTEGDIRGVHFCTLNLERSVQLVLENLHWAGGSP
RIQNRLIVDAPGQIIHPPQPDSDLYITPTSAADSATTGLTSIPHTDGDAGRGELNNAASW
DDFPNGRFGDYKSPAFGDQGPWGGVGITRSEAFAQWGHPKTLDDLMNLFLRHLHSQIATT
PFSSAPLSRESSSILSHLEKLTRKGWWTVGSQPTVDGVSSSDEIVGWGPRGGYVFQKAFV
EFFAGKEDVERIVKKVREEGQGLVDYFTGNIQGECWSNVPDGGRNAVTWGVFPGQEITQT
TIIERESFLSWKDEAFSIWAEWASFYRPGSDERKLLEGIQNERWLVSLVHHDYKDPEGLW
TFLFGGMPVV
>A0A3B9PS32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MSIGRSLKERFAEDKPLFSVEFFPPKDEAGGLRMLKTAALIQPYRPDFVSITYGAGGGTR
STTLRYAKLLQQEHGFEVMPHLTCVGHTRDELLEILEEFAQAGFRNIMALRGDPPKGETT
FKPVAGGLSYGSDLVSLIRENFPEFGIGVGGYPEKHPEADSMGIDLKNLKTKVDAGADFI
TTQLFFNNSVYHDFVERCRKAGIEIPVLPGLLPVLSIGQVRRFCAMCEAGLPSQLERNLE
NTDETGQPVVGAKWALEQIKDLLSRGAPGYHLYALNKSQSTLQILEGLGES
>A0A7Y7M524|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. SDTb3-6|TrEMBL
MEIIPTRDIVPAVLAHVPAGTTLTVTCLPHHGINRTLEAAAALAGHGYTVVPHLAARLVA
SRGELARILRICTASGITEVFAIGGDGAAPAGPYPSSEALVRDLAELGGGTLKIGVAGYP
EGHPSISGPQLLESLLAKQELASHVVTQMCFAATAIAGYMDGLRNEGVLLPVWAGVAGSV
PRAKLLQLAAKIGVGSSLRFIAGKGELGRKLLGGSRYQPAQLVAELETQPLPPAGIHLYS
FNNLDPQLRQQAAASRR
>A0A7D5BG83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. FDAARGOS_724|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQRNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHKIAGIVITPHMLRVLAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVET
KKELVPQLAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A5D4SSR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus infantis|TrEMBL
MSLLDKMEKEIIIADGAMGTLLYSYGTDFCFEELNVSQPGHIQNIHQAYIDAGATLIQTN
TYAANYLKLQRYGLEDHVKEINSAAVTVARKAAGNHAFVAGTIGGNRGIKPHSISIEEIK
RSFREQLYCLLMEGVDAILLETYYDLKELETVLSIARKETALPLIAQVSLQETGIMQDHT
PISEALSRLDALGADIVGLNCRLGPHHMLLTLEEVPLPQKAYLSAYPNASLPAYTDGKFH
YEGDAEYFRQSAKAFRNQGVRLLGGCCGTTPAHIRAFSDELKGSPPLEKKEVREPKAKIR
IMPKEAQRDLPPLQDLVKKRQSVIVELDPPRKLETDKFFAGAKALQDAGIDAITLADNSL
ASPRISNEALGYLAKNRLGLRPLIHLTCRDRNIIGLQSHLMGLHTLGLHDILAITGDPAR
VGDFPGASSVYDMSSFELIQMIKQLNEGRSISGKDLGQKAAFSVAAAFNPNVRSLEKAVQ
RLEKKAECGADYFITQPVFSEEKLMEIYEATKHMEQPIYIGLMPLTSSRNADFLHNEVPG
IKISDKIRERMNSLKDDPLQSVREGISISKELIDAAAELFNGIYLITPFMKYELTAELAA
YARSEKLKTARRSRNAKDFSI
>A0A2U1JSJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium laiguense|TrEMBL
MKVTQHIENAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKMGGNNFAVDLVSQINQLNSGKYLHDVMDVDNLADFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDKCKNNAEIRQVGIEWAIQQSIELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A6F8PX78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiosulfatimonas sediminis|TrEMBL
MQSQQKYAQKLSLEFFPPRTEKGTEKLKSVIQDLGAINPEYMSVTYGAGGTTQEKTVETV
RYIQRETPFSAAPHLTCIGATEESVLHLLNEYEAMGVKRIVALRGDLPSGMMDPGEFKYA
SDLVAFIKQQKGDTFHLEVAAYPETHPQARNCDIGIKWFKHKVEQGADSAITQYFFNFDS
YRYFIDNCEKNGIDLPIIPGIMPITNYENLIRFSQGCGAEVPRWLKCRLESFDNDQAGLL
EFGQDVVTELSQKLLDAGAPGIHFYSMNNTQPTLAIAQALTLK
>A0A2E6X7J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetovibrio sp|TrEMBL
MWKSGSNLEKILAEGHFAVTGELGPPKSMNTKLVHNKIDMIKDFVDAANVTDNQTGIVRL
SSIGTGILMEQEGLEAVIQMTCRDRNRLAIQSDLMGASVHGIRNVLCLSGDHQSFGNHRG
AKNVHDVDSMQLIRMVQEMRDLNKFQGGEEIKGGGPRLFIGTAASPFSSPIEMRPLRLAK
KVAAGADFAQSQMIFDMKLFKEYMKRVVDLGLHEKISFLAGVGPLKSPVMARFLHEQIPG
IVVPEDCIERIEDAGKGIDSDDKKALQEAYRAEGIKLCIEQIQEVQEIEGVAGVHIMAIQ
WEAAIEPIVRGAGLYPRPNLGPTG
>A0A068QMZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus doucetiae|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPSTTEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKEKTGLDAAPHLTCIDASREELRNIAHDYWQNGIRHIVALRGD
LPANGGKPEMYGSDLVGLLKQEADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPV
>A0A1Z5J579|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Secundilactobacillus silagincola|TrEMBL
MKVVDCFKERPVISFEIFPPRPNASEKSIERFYDNLDVLASLKPAYISVTYGAGGSDNKS
GTLDLCRYIKQHYGIEVVPHIPGINFTTSAVKSYLDELKASNIENVLALRGDLPEDGQIK
GDFQYASDLVTEIKRDGDFNVLGACYPDVHPEAKDSVDDIKNLKCKVDAGVSQLITQLFF
ENEHYYQFLERCELADIDVPVQAGIMSVVNERQIKRMATMNGVGLPQKFLRMMNHYQDNP
VAMRDAGTAYAIDQIVDLLSEGVDGVHLYTMDNPVVTKRICGAIETLI
>A0A1Q5H209|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. TSRI0369|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTQAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWIAHPEGVRYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAYFVR
KCRAGAEFAVTQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFERVADDPEAVRRLGVEQASEMCEKLLDEGVPGIHFITLNRSTATREVWQRLR
AAARV
>A0A3C2C1B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp|TrEMBL
MFPTRIEIIPSTGIIDQVQALVPLTTTLTMTCLPHHGIERTMRTSVELSTLGYTVIPHLA
ARSINDRAELTRIMRECDVAGIGEVFVIGGDRKQPAGPYGSALPLLEDIAQYTGGRMRAG
VAGYPEGHPTVAALDLLDALQDKQHLATHLVTQMCFDAPKILDYAALLRREGVDLPVWAG
VAGSVPRTKLVALATQIGVGSSLKFLSRKGPLARKLLSGDRYSPHALVAGLESQPGIA
>A0A2D3D5L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium choerinum|TrEMBL
MPIFSLEIFPPKRTAPVGTIYDTLDGLQGLSPAFISVTYGTGKSVDRTATARIANTVRAE
YGIPAVAHLTAQYLDEAGADEALDLFDQAKVAGILALRGDRNPEREPANVFSHASDLAAF
IRERRPDMPIYGACYPEKHPQAASLDEDIDNLKRKVDAGVTHLISQLFYDDEDFLRFRDK
ARAAGIDVPIEAGIMPVVNAGSVRHMADLCGSRIPERLAVMLEMWGQDPASLKEAGVVYA
SEQIRDLVARGVDGIHLYTMNRPCAARRIWANTKVFFA
>C7YTQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium vanettenii (strain ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL 45880 / 77-13-4)|TrEMBL
MDRITDRIAALPADGSYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRREE
YRDPDDSEDDGGQDFNWAADLVKYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVEAGADFIMTQLFFDIKAYEHFENTLRDHPSGAFKTLPIIPGLMPIQSFQMIKRT
TKLSHAQIPDDILERLNAVKGDDERVKMVGVDIVSELVEKVKDIKSKTPGPKGFHFYTLN
LEKAVSFILERTNLIPEPPEDEEALVVDDAIPIPALLVNGSSNLRSGSHSRSRASRRHSS
VGSDPHNRVIVGDRPATHPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDF
PNGRFGDARSPAYGEIDGYGVSLHMSITQAVKLWGHPKTRQDINDLFVKHIQGQLSAIPW
SEEELLAESSTIQPHLLRLNQKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEF
FIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVSSDKGGHVDGSSGAGPSTNAVTWGV
FPGKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSDSEKLLSGIKDEYWLVNLIHH
DFVEKDALWQVLSS
>A0A2I7K7Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter inhibens|TrEMBL
MTTPDISFEFFPPQSLEASFRLWDTVQTLAPLAPRFVSVTYGAGGTTRDLTREAVATLHN
SSGLNVAAHLTCVNATKAETLAIADQFAEAGVREIVALRGDPPKGAAGFEPHPEGYANSV
ELIAALAERDQFSIRVGAYPDRHPEATSARADVDWLKRKLDAGADEALTQFFFEADTFLR
FRDDCAKAGIDTSRITPGILPIENWKGARNFAKRCGTTIPAWIDDAFDKAIRDGREDLLA
TALCTELCSDLMDNGVDKLHFYTLNRPELTRDVCFALGITPDVSLENVA
>A0A233RAK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanimonas doudoroffii|TrEMBL
MGFHSARHVEALNQSLSELNGDINVSFEFFPPNSEKMEQTLWHSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIQDKTGLIAAPHLTCIDASRDELRNIARDYWNNGIRQIVALRGD
LPQGMEKPDMYAADLVGLLKEEADFDISVAAYPEVHPEAKSAQADLLSLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTIGIDVEIVPGILPVSNYQTLLKFAGFSNVRIPAWMHQRFA
GLENDQNTRNLVGASIAMDQVRVLSREGVKDFHFYTLNRSELTYAICHSLGVRPPVATVA
E
>A0A3T0Y4Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. MN05-02|TrEMBL
MPPATYPALSYELYPPRNAEAENALWTTIRRLERTRPDFVSVTYGAAGSNRETAVDLLRR
LLTETTLKPLAHLTSVGSSRAELTGIVERLIGGGVRGILALRGDAPEVSEGQPGEVEHAD
QLVRLIREVEAQRTAHLAAGRVSVGVAAYATRHPDSPSVEQDIEVLLAKEAAGADFAITQ
VFFRSADYARLVARARRAGVTIPIIPGVMPMTSSRRLKKLGGLAGIDVDEGLRARLDGAR
TDDERRRIGVAATVELARAALDDGAPGLHLYTFNEHSAALDVLDALDLERPPEAGLAASL
>J3JK11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces naeslundii (strain ATCC 12104 / DSM 43013 / CCUG 2238 / JCM 8349 / NCTC 10301 / Howell 279)|TrEMBL
MTYRPTFVTEPVPGTGRRSGADQECLPRVRVVQEETNPSEGVLAHVLESSTIPLMAHLTC
IGYCKQEAVDIVTRFLRMGVRRFLALRGDPPAGARADEVAGELRHADDLVRVIREVEADF
FGDGKRHVTIAVAAYPATNDHIEAIEVLAAKQAAGADLAITQVFYDPADYVALTNAASYA
GVSIPILPGVIPLTDLRRLARLEALTGVRVPDALRSSLGSASGATLVERGIGATLDLATA
LLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDAVDRGYLQATPGRGPS
FLRSGSPGAAASPRHPVQPHNTITKENA
>A0A850LM63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria pomeroyi|TrEMBL
MTAPQISFEFFPPKNLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLNVAAHLTCVQASREETLAIADSFAQAGVTDIVALRGDPPQGEGRFTPHPGGFANSV
ELIQALAETGKFAIRVGAYPDIHPEASNAQADIDWLKAKLDAGADEALTQFFFEAETFFR
FRDACAKAGIDKQITPGILPIENWKGARNFARRCGTHIPAWVEDAFDKATRDGREDLLAT
AICTELCSELIEGDVDKLHFYTLNRPELTRDVCHALGVTPKVALQNVA
>A0A8B2SAC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. GER_MD16_1505_Eko_090|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7J3ZBH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidilobales archaeon|TrEMBL
MNTCPKRMINGPCGGYRDTICEDDRLKCVWILAYYSALKRGTIDKMFQLKLDPGFKVASY
RPVTKRARGIVERILFGKTVIIYEYTPKPYTTPEVLVKELEGIAGIYHGVDFVDNPGGYP
IPSSLPYAAITKNSYRSLHVSIQITARNRDRNQVVSDVLAASLAGLDAIVATTGDLQLDE
KGVWDLDAPRLIYLARLVLDLGIDHTGRRVGIGGENMVIAASVNINAEPLEPEILKIRVK
IDAGAELFITQPVFDIERFRIFQRSLGEKIRSSFKIPVIAGIIPVTSKKIHQFFEKKVGI
KIPEKISVELKRDKIDREALIKANLDVIEKIVREINHSSYYISAFGDHRLGIEIAKVVRS
IVG
>E3NWB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis remanei|TrEMBL
MSQLSQYFAQNQFCCLVEYLPSKQEMLPVATQLAGFPVCMTLSDRVRSDDDIAPLIAAQS
YPQQIEKVVHYAGKGRDIHDFNLFLTQAKQHGQQNLLLLTGDKLKQHHDGRGSHARTRYL
ESVNAVIAAKQQGGFHIGVALNPFKYSQAEKQAQYLKLHKKLQAGADYIITQLGFDLVAL
KQAHEFLIEENYTQKILACVMPLTLARAKFMLKHNVAGIVITPHMLEVLAQEHDSDQTEN
TYLRCALQILICQHIGYAGVHLSACHKADEQAILTGYIEQYRHLDLKQCQQLWAQLWQLK
TGNELRPAVVEKSKLRNLQQKVKYQFLDTIHSTMFNSSLVKGLGAYIFSANFWNKALAAK
LLLQAEYLSKHFIVGCESCGQCRLAETLYICPETCPKGLANGPCGGTHLDRCEFGDRECI
HSVKARLAEEVDQIQVLKKQLIPTVPIEVRGTSSWKNWYVKQ
>A0A6A2Y1M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hibiscus syriacus|TrEMBL
MKVIEKIQSSPQDQGKVVSSFEFFPPKTEDRVENLFERMDRMVAHNPSFCDITWGISGST
VDLTLYIANKVQNIICVEAMMHLTCTNISFEKLDHALEIIKSNGIQKVIALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDYSGITVAGYPEAHLDAIGDNGVATPEAYQNDLAYL
KRKVDAGADLIVTQLFYDEITAALEPIKDNDKAVKAYGIHLGKEMFRKILANGIKTLHLY
TLNMEHDHILKANGMFNC
>A0A560MAP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. ERR 942|TrEMBL
MSHIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLHEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRTDALVAERLHQISEGREENQQAMAEIAA
HHTPPQAH
>A0A1I2GD23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter antarcticus|TrEMBL
MKITDHISNAGDKTLFSFELLPPLKGKSIHEIYKAIDPLMEFNPPFIDVTYHREDYIYKQ
HTSGLLEKVSYRKRPGTVAICAAIMNRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARQADSGFIPTPGGHAFATDLLGQVKSMNEGRYLFEDHSAFQTNFCIGVAGYP
EKHFEAPNLKADFKYLKQKVDMGAEFIVTQMFFDNAKYCEFVANCRANGINVPIIPGLKP
ITSSKQLISLPKIFHIDLPEDLTEAVQACKNEEAVKEVGIEWMIQQCKELIKVGAPVLHF
YTMSNPEPTKRIARAVF
>R5HAZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:24|TrEMBL
MIKDLFSQKQTLSFEVFPPKKDDEFTNAQNVLHQLSELQPDFISVTYGAGGSRSKRTVEL
ASFIQNSLHIPAVAHMTCVGSSKEDILTVTDDMKQAGLSHVLALRGDRPTWMDDAQFENR
AFAHASDLTRFLKEHTDLEIAGACYPEKHFEAESLDSDIAYLKEKQEAGAAFFITQLFFE
NDSFYRFLEKKNHAGITLPVCAGIMPITSAKQLGTTVTLSGSSVPKELADIIATYGENPE
DMRKAGIDYAIRQILDLKQHGADGIHIYSMNKPKTTRTIVEAIR
>A0A3M7STU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachionus plicatilis|TrEMBL
MSQIDTAISPIIENFQSKLMLDSNLISFQNGLPNPVCPSTTTHESLIDKIKKKIENKETW
FSLEFFPPKTVNGASNLISKLEFLGTGKPLFCDITWHPAGDPASDKPTSSMKISNVMLNY
CLLETMLHITCYGQTKESMKQYLDKAKSIGIRNLLALRGDPAVGTEWRYQENGFNYATDL
VRFIRENYGILPIQSYDSLRHICKLSKLEVPQNIVSAMEKIKDNDEAIRIYGIEQAVNLC
QELMQAGVFGVHFYTLNRDVAVTEILRRLDLWNKDSEPRHLPWKSKQLCSYSRPDEDVRP
IFWSIRPKSYVCRTSDWDQFPNGRWGNSSAPSFGDLKDYHIFYSKINTKECLAQWGHNLN
DETDVWNVFASFVSGKPNKIGVKITSFPWCEEGLASETSLLTDELERFNRQGILTINSQP
NVNGAPSSDPVIGWGSPDGYVYQKAYIEFFISKSFLPFLLEALEKYPRVIYHIINKSGDI
NLTNCTLLNPNAVTWGVFPGKEIVQPTVVDPISFMSWKDESFNIWTDYWGKLYEPNSTSR
ELLEQISNTYLLVNIVDNEFQKENCIWSILNEMLELKAKNMLKISLKLA
>B2V845|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurihydrogenibium sp. (strain YO3AOP1)|TrEMBL
MKIIDKLKNTKVSISFEFFPPKTEEAEKTLFETISNLQPLNPTFVSVTYGAGGSTREKTR
DIVKKIHEETKLTVMAHLTCIGHSKQEILSILDDYEKIGIENILALRGDIPLNFEKSDIL
SDGCKHASELVSLIRETYKDYFCIAVASYPEGHPESPNLEREILYFKKKVEVGADFSITQ
MFFDNSYFYEFLEKCEIAGINIPIIPGIMPITNFNQIKKFASLCGATIPEEVVQKFEKYA
DNPEETKKIGIEFATLQCMDLIKHGVKGLHFYTLNKSDATIKIYENIKDYL
>A0A250EMW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. H2931|TrEMBL
MKVTEHIARSKGKTLFSFEIVPPKKGNSIEELYRNIEPLIEFKPPFIDVTTSREEFFYKQ
HPNGLLEKKITRMRPGTVGICSAIQYKYGVDTVPHVLCGGFTKEETEYLLVDCFYLGIDN
VMALRGDARKEERYFEPTKDGHTYAVDLVRQIKDLGRGKFLHDVIETDYGTDFCVGVAGY
PEKHIESPSMTFDLARLKEKVDAGADYIVTQMFFDNQKYFEFVEKVRLMGIDIPIIPGIK
PITTKKHLNLLPQVFKLDLPEILVSELEKCKTNEDVKQVGIEWAIEQSKELKLWGVPTLH
YYSMGKSDNIVDIVSKVF
>A0A2T9K5W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter endophyticus|TrEMBL
MTLPPTRRVIGPVARAGERPAGAARPRVSFEFFPPKTEKMEESLWEAITRLAPLDPAFVS
VTYGAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRAEVDEVIHDYWNIGVRHIVSL
RGDPPPGEGGIGGVYVPREDGYKNATELTAALRGVAPFEVLVGVYPEKHPESPSLDHDID
VLKAKVDAGATLGISQFFFDIDAFLRFVDKARAAGVTIPIVPGVMPVTNFNGLKKMSAAC
QTSVPSWLANLFDGLDEDPETRRLIACSVAAEMCAKLQEQGFNDFHFYTLNRADLVYAIC
RVLGVRETAPAREAAA
>A0A2I0R0T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brumimicrobium salinarum|TrEMBL
MKVVDHIAEAKDTLFSFEILPPLKGKSIQSIYNGIDPLMEFKPKFVNVTYHREEYVYKER
DKGLLEKVAIRKRPGTVGICAAIMNKYHVDAVPHLICGGFSKEDTENALIDLQFLGIDNV
LALRGDPIKTESTFRPAKNGHKYAVELIKQVQQMNEGNYTLDEIKLEPTDFCIGAAGYPE
KHFEAMNMATDLQYLKQKVDSGAEYIVTQLFFDNQKYFDFVKRCRAVGINVPIIPGLKPI
SKLRHIPFLPKFFHIDLPDTLSNELLKCKSNEDVRELGIEWGIQQSKELKEAGVPCIHYY
TMSDSSEVKEIARELF
>A0A0X8P1H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLREILQTYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANVTADMDHFVAKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQNLLDNGAPGLHFYTLNHAEAPLAVWKELSV
>K9Y8F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halothece sp. (strain PCC 7418)|TrEMBL
MMSRFRQAVEANEFLVTAEVTPPKGGNPERMLRVAQALKGRVHAVNITDGSRAVLRMSSL
AASVILLKHDIEPVCQVACRDRNLIGIQSDLMGAHALGIRNILALTGDPVKAGDHPKAKA
VFNLESVRLLKLINKLNEGTDFNDKPLPDGELELFAGAAVDPQSDSWSGLQKRFERKVEA
GAEFFQSQMLTDFDRLEKFMNEVASPAKKPILAGIFLFKSAKNARFIQKYVPGVHVPEEI
IQRLDRAQDPLQEGIKIAAEDVQKARELCQGVHMMAIKKEEVVPEILDLAGVKPVEGVKL
PTTAQVR
>A0A2M7PZ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium CG_4_10_14_0_8_um_filter_49_80|TrEMBL
MKLRDIFSKAEKPLLSVEFFPPKTDKGEENLWTCIQELKPMHPAYVSVTYGAGGTTQDRT
RNIVLRIKEQTGLEPVAHLTCVGATQAQLNALLEDYRTHGLDNILALRGDPPEGMDKFEA
TSGGLSHATDLIEFIHQRNHFSIACATYPEGHPESTHGVADDIQYLKLKQDNGADMAVTQ
YFFDNDTFFRFRDAAHAAGVTLPIVPGIMPITNFEQIVRFSGMCGASIPEKIHQQMSPIQ
QNLDDVKKLGIDIAISQCQALLSNGVPGLHFYTLNKSEATLAINREL
>A0A8G0V9K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruficoccus sp. ZRK36|TrEMBL
MLSAGEPVFSVEFYPPKTEEGARQMLRTAKALSAYQPDFVSITYGAGGSTRERTLEYGEL
MRDLFHFEVMPHLTCVGHSRDELAAILERFQQAGFRNIMTLRGDPPKGQTDFQPHPDGLR
YASELVRFIRERFPHFCLGVAGYPEKHPESPSLESDLDHLQHKAAQGADFITTQLFFDNA
DYFAFVEKCRARGIHQPIVPGILPALSLDQVKKFCGFCQAKLPEGLMSKLEAAQGDEEAE
RQAGVEWAHMQVKHLLEAGAPGVHLYILNRSDSAIDLVQALHADGVIKR
>J8B977|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus BAG5X1-1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINRAAVNIAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FILLEQAGTLLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRLRAHVTLAEKAKKQITVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSVLGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLTAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEVTKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7W1FA71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
AHMSAAAGAAFVAAAGIEPTLQLTARDRNRLSITAELLGAWALGARNVLCLSGDPIAIGD
HPDAAVVNDLSVREVVGLVRRLRDEGTTLSGAAIEEPPRYLIGVADLPLADPYDPVRLEQ
KLDAGADLIWTQIAYDVEALAAWAESARARGVFERAKVLIGVVPLRTEKGARFMNDKLPG
VRVPPGMLRALEAAGDDAEEVGRDLTIEVVRGIRAIPGVSGVHLMGMGHDASVRAVVEGA
GLFPRPTGA
>A0A6I2X3Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGHAVTVPSSLMSTRPTISIELFPPKDSAGEERLWSAIASLREISPDYVAVTYGAGGSTR
DRTIRITSEITARTQLPTVAHLTCVGSTRDELIDVLNKYKSAGIRSILALRGDPQGGPSA
AWTATPDGLDHADQLVALASEVGGFTIGVAAFPDGHPASQGNFDRDIEVLLRKEELGATF
ATTQFFFTAEKYFDLVERLRSRGSHLTVMPGIMPISNVKQLIRMAELSGTPIPSDVEQKF
LALDGDSDAVRDYGRELATTLCQKLLAGGAPGLHFYTMNTSTATKEIFENLGL
>A0A7V9CVJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSTPFEKRLQNGPIVVADGGMGTLISGAAPRLRCPEEANLRAPETVVSLHVSFIKAGADL
IETNTFGANRRKLAAHFLEEDVERINSTAVKLAREAREIAGRDVYIGGSIGPLGELADVT
PEYQRRIFGEQAAAQHARGVDLFLVETFFELEELLIAIAAVREVASLPIVALLTFDEQGE
TLGGVTARQAVEALADSNLAAIGANHGAGIHAALTALTEMHATDDSLALAAMPNIGLASM
AGSRVVFPHATPEYFADFAAHARDLGAKIIGGCCGTTPGEIGAIAAAVQAKRVPSSPLIV
QEREVTLSVVEQAVDTRLASMLRAGQWVTSVQLDPPLGGNHRGMLEIAASLENGGAGFVD
INDNATARAGMSALMLSTAIERTTGLETIPHLTTRDATVLGLESQLLGAHAEGIRNILAV
TGDPPEVGDYPGSSGVYEVDSIGLVQLLSHLNRGEDYNGRAIDAATHFYTGVAVNPSADD
IDLEVERYRRKIEAGADFAMTQIIFDLELMDRFFDRFGGPSPIPVLVGVFPVWSHPLALR
LHNEVPGIIVPDHIQEALREAGPEGPKVGMELARELVEASRGRAAGVYLVAPFRRPLGIL
ELLADAA
>A0A6I7MVA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mongoliibacter sp|TrEMBL
MKITEYINQAEKPLFSFEILPPLKGQSLNDLLVGIEPLMEFKPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAALMNRFQVEAVPHLLCGGFTKEETENALIDLNFIGVQNV
LALRGDAPKNEGKFVPEPNGHEYTTTLVEQIIGMNHGKYLHEETETSFHTDFCVGVAGYP
EKHFEAPSMKFDLKFLKEKVEAGAEYIVTQMFFDNEKYFDFVKKVKAAGIDVPIIPGLKP
ITTLGQITMLPRTFFLDLPDDLLDELIKCKTNADVKQVGIEWAIKQSKELIANGAPVLHY
YTMSKADATYKIAKEVF
>A0A8I0FQW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterales bacterium SAG-MED15|TrEMBL
MKFSLEIGPTADLSTLPALKDIYITMLPGGDYRETAQQAINLVKKGYNPIPHFPARSIES
DNQLKEYVDMCKDGGVKQVLVIGGGREPAGKFDSSYQLLETGYFEKMKIGIAGHPEGSPD
ISDSDLEKAMIDKKPYADYIVTQWLLDPQPIIDFISKQSIPVHVGITGPLKISSLIKFAN
IVGAKNSLNFLKSNFSKALDLLKPKDPNDLIGKLNSHTDYFHIYTFGGLKETNKWLMENK
YV
>A0A7N0VGQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kalanchoe fedtschenkoi|TrEMBL
MKIIDKIKAAQEQGKVSFSFEFFPPRTEDGVENLFDKMERMVAFNPTFCDITWGAGGTTA
DLTLDIANRMQNMMAVETMMHLTCTNMPVDKIDHALATIKDNGIQNVLALRGDPPKGQDK
FVQIEGGLGCALDLVQYIRSKYDDYFGIAVAGYPEAHPDVIQLETGLATPEGYQGDLQYL
KKKIDAGGELVVTQLFYDVDTFFKFLDDCRQIGITCPIVPGIMPINNYNGFKRMTGFCKT
KIPAELSASLEPIKDNEEAVRSFGVHLATEMCKKILAHGVTTLHLYTLNMDKSAVAILMN
LGLIEESKISRSLPWRRPANVFRTKEDVRPVFWANRPKSYVSRTLGWDEFPHGRWGDSRS
PSYGALSDYQFMRPRVRSKKLQAEWAVPLKSIEDIQERFSKLCLGELKSSPWSELEGLQP
ETKIIDEQLGSINLKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCTQEKL
NTLVEKAKRYPSLTYMAVNKSGVWISNVGTTAVNALTWGVFPAKEIVQPTVADPASFLVW
KDEAFEIWSRGWAQLYPEEEVSSKNLLHEVQGSYYLVSLVDNDHIHGDLFGIFKEL
>A0A6L6DFL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
PPKDEAGEANLWSAFQKLLEVSPDYVSVTYGAGGSNRERSLAVVDRMAAKVLTIGHLTCV
GATKQSTLEILQHFERAGVGAILALRGDAPKDDPDALGKGELKTALELVDLVHESTKLEV
GVAAFPEVHPESPNMEHDSKVLALKQDAGATFAVTQLFFSVQAYTDLVASAQAAGVTVPI
IPGVMPISNAKQVVRMAELSGAAIPAELIAKFDAAADEDEAREIGMAYSTQLAKDLVTAG
APGVHIFTLNHHAAAIELARGAGLCR
>A0A7K0QSM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNTPPTAHRVGETLRKGGRTYSFEFFPPKTDEGEQQLWQALAELEPLKPTFASVTYGAGG
STRDRTVRITAQMAARTSLAPVAHLTCVGSTITELEEILAEYAAAGVSSVLALRGDPAAG
PGTPWVSTPGGIDHADQLVELIRQTGDFGIGVAAFPDGHPESSTRDQDAQVLARKQDAGA
EFAITQFFFRASDYFDLVERAATHGCDMPIIPGLMPVTNVAQIQRFAALSGAAFPADLAE
QFETISDDAAAVQQLGVDVATDLAAELLAQGAPGLHFYTLNRSSATRQVYEALALRDV
>A0A7K0X625|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTYISDLLAAGRTCSFEFFPPKTDDAARALEQTIAELEPLDPSFVSVTYGAGGSTRERTR
DVVINIERNIGITAMAHLTCVGHTRAQLDSLLDEYKAAGVSNILALAGDPIVDDNGVVAE
SEFEFAMELVELIKEKSGFSIGVAAHPEGHPRSEDLYSDRRHLADKLNVADFAITQFFFE
AEPYLRLVDGLSA
>A0A7X9KGA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARISDLLAAGPTYSVEFFPPKHEAGWLSLGRTISELEHLAPDFVSVTYGAGGSTRTRTA
DLVSWVRR
>A0A7K0P0C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTLRELIDNRTRPIVTAEFPAVNGGGLEAIRAKLEPMLPFVDAINATDNPAAHAHASNVS
IAIALKTLGAEPIMQVVCRDKNRLALQADIVGAALFGVENICALTGDDVTAGDEPEARRV
FDLDGPQLIAVATRLGQGQYLSGRTLTPAPTLLVGAVENPAAPPLKYRVERAALKSDAGA
RFLQLQICYHPDRLAAFVAGCVERGIDTRTALLPTVCLTKSVHSLAFMHDRVPGIDVPQE
IRDRLAAAPDAAEESYQITLELSRHALSLTGVAGLHITDFRHDGSLGRLVTELGLRPDVV
ATTA
>A0A6J4H0V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Actinomycetospora sp|TrEMBL
PRARRVTTGPAGLALRLHDGVDVDTVLTLTSWQTSMLALQADLLGLHALGLRAVVCETGN
PPVHAEQAVRDGVWEVDGAELLRMAAGLNRGVDADGVELGVATSFRLGARFTPGAEDLDH
EAARTVAKVEAGAEFLVSRPVFELERLRDVVDALDAAGCRVPVLASVGALTGFSQAEHLR
HEVPDVVVPDEVLEAMRGAGDVPDAARTGLALAADLVAQAADVVEGVVVRWSGPALPGLD
PATAVARLRAAAGTGARVRR
>A0A7W0P4K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKVIEHLANATNPLVSVEIIPPRRGRNVERIYEAVSSLMPYEPPFIDITSHAAETVWDEV
PGGTYRRRVTRKAPGTFGLCAAIKYRFDVDPVPHVLCNGFTREETEDSLIELNYLGIENV
LAIRGDGERRVPPDG
>A0A6I2ZB78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSALQEKLENTKETVFTAEFPSIDGAGMDKVVKNAERLAPWFDAVNATDNPAAHAHASNT
STAIAIKMHGLEPIMQIVCRDKNRLAIQADMMGAALHGIQNISLLTGDDVTAGDEPEARR
VFDVDGPQAINIARILTTGKYLSGRKINPAPEFYISAVENSSAPPFDYRIQRALKKHQAG
ARYLQLQISYHPDRLEAFCTGVAKIAPALHLIPTIVLVKSAKPMDFMNEKVPGIDIPKDM
INRVASASDQSAEAYQLTVDLAKHALTLPGVRGLHVTDFRHDDSLASFMHELGRKPRN
>A0A6I3EGN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MERMTVSVEFFPPKDEAGVARLWSASSALESISPDFISVTYGAGGSTRDRTIQITKEITQ
RTGRNTVAHLTCVGSTKAELIEILAQYKSAGIKTILALRGDPVGGPTSPWVTTPGGFDHS
DQLVELAMSQGGFEVGVAAFPDSHPASGGDFNRDIDVLIRKEELGASFATTQFFFDSAKW
ETLVSKLQARGSKLPVIAGILPVTNVKQLQRMS
>A0A6I2KWF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella guangzhouensis|TrEMBL
MNVVSSEALPVPPHAVDTRLKERIAAFMRRASTEVTTHDESTLPQLADTLPRGTTVYVAH
TPKAQFDDVLRVSLKVQAAGFLASPHLVARRLPSEAAVRNGLRMLSDAGITQALLVAGDR
DAALGPYANTLELLASGVLDDCGLRALGVAGHPEGHPHVVKADLWQALRHKQAFADRTGI
AVHVATQFGFDPQGVHDWAAQFEQHGIDLPVHVGIAGPTSVAKLLRFAIQCGVGASLTAA
SKNMKAFSNVARQGATPEEIVPALVRLGAGETAARIVQPHVFAFGGTIATANWIRAVRNE
EFDLQPDGAIEVRR
>A0A1Y1KY63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photinus pyralis|TrEMBL
DIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASFIVTQMFYDADNFVRWVGKVRERGINI
PILPGIMPIATYASFLRRAKHMQCKVPDHWMTALEPVKNDDVAVREIGKTLVAEMCRKLL
ANGIYHLHFYTMNLAQATRMLLEELTWAPCAERPLQH
>A0A7V9V5Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAKIADLLAAGRTFSFEFFPPRSDDAERVLEKTLLELEELQPSFVSVTYGAGGTTRDRTR
EIVTYINRDTSMTAMPHLTCVAHTCADITDIVTGYRDEGFENILALGGDPPALSDGEPEP
EGDFEYALELVELVRSIGDFSIGVAAHPELHPRSNKNREMDRDHLATKLRSADFGVTQFF
FRAEDYLSMVDDLAARGVDKPVVPGIMPVTNAKQVQRFAQMSGAEFPPDLAARLEAASDD
PAEVGRIGVEVATQLCQDLLDGGAPGLHFYTLNRSTATREIYANLGLAPTS
>A0A7C8GIG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rouxiella sp. S1S-2|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPTFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATPSELRKIAQDYWQSGIRHIVALRGD
LPPNSGKPEMYATDLVHLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIVPGILPVSNFKQLQRFAKMTNVRVPNWMTSMFE
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEIPASL
AL
>A0A432HV42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poseidoniales archaeon|TrEMBL
MSSSTSSGTGISSGFPSVNLSNSSESIWPNCLPSICRLFSSIHTGGAPVVKITESCFEAT
GHTSVICDFSPPRSGDQVVVGQAPIGADFISVAYNPGRAVRTNAAMLAAAIQNSGNDAVF
TLATRDMNKLALQSQLLGAQLLSVQNVVVVQGDPFGEQDQKRVASVNDYSPTGLIAAIAQ
MNQGQDFKGSKLGQPTDFCIGAAVDLGRGIEEEAQLAVRKVQAGAEFLITQPIFNVDHVA
RYRESFGYHAGKAGTVPIYFGLQILEKDGVLFSSVPESLRAELEGGRTGVDIALELYGKF
QEARLNNIYLMPPIKRGGARDYEAAKEFLGKIKRI
>C8XCS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / CIP 104796 / JCM 9543 / NBRC 105858 / Y-104)|TrEMBL
MPTVPERLATAGPHFSVEFMPPRSDADEDVLWRSVRRLEPLRPAFVAVTYGAGGSRRERT
IRVTQRIAEETTLLPVAHLTAVGHSVAELRQIIGSYAAVGVNNILALRGDPPGDPNGEWI
AHPQGFEYTGQLVALARSLGSFSVGVAAYPDKHPRSADLASDTRFLVDKINAGADFVITQ
MLFSAADYERLRERMERAGARVPVLPGIMPVTSHGRLMRIVELSGQRVPEQLADELYAVR
EDPEAGRAIGMEHAVRMSQDLLDAGAPCLHFYTFNRSKATIEVLSALGMTPAMRR
>A0A0L8A6I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas geniculata N1|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGWRR
>A0A537W2J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSLTALTSAEISLPAEADGTRVNERIAVLADTVDVVGLTDNHAGQPRMSPLAAVALAREQ
GVGTIVHVSCRDRNRLALQSQVVGAAALGAEAVLCVQGDPVPGIEHVADMTATQLIASAS
PWSAPHPLAVGAVVNPFAEDVDRELRLLRRKIDAGATFVQSQMIFDLGRLEA
>A0A2N8B4T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FW305-25|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A358SN42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTDDGQTRASRLRQVLAAGEFAVTAEIGPPRGADAAPVARKAAHLRGWVDAVNITDNQSA
SVRLSSWAGSLTALAAGVEPIMQLTCRDRNRIALQSELISASAMGIPSVLVMTGDHPRHG
DHAEAKPVFDLDSTQLLSVARTMRDEGRLMSGRLVEPPPSWLLGAVENPAAPPAASAERL
AAKIAAGAQFVQTQFIFDVPAFADWMAHVRDLGLTGQCAILAGVGPVRSLRALAHLQRVP
GVRIPAEIAERLSAAGPDHIAAAGERLCAETIARLREIPGVAGVHVMAVGAESHIPRILQ
QAGLRSGHAAGAAAHAR
>A0A1H4XHT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum sp. MAR_2009_124|TrEMBL
MKVTEHLKNAKGKTLFSFEIVPPQKGQNIQELYNNIDPLMEFNPPFIDVTTSREEYIYLP
KEKGLLEKKVTRMRPGTVGICASLKYKYNVDAIPHVLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDARKDQQYFKASDGGNNYASDLVKQISDLNKGKYLHEIIETPYKANFCIGVAGY
PEKHFESPSLATDLKRLKEKVDAGADYVVTQMFFDNKRYFEFVKKAREIGIDVPIIPGIK
PLAVQRHLQILPQIFRLDLPEELVEAVEGCKNNKEVRQVGIEWAIQQSKELVEGGVPVLH
YYSMGKSSNIKAIAKELF
>A0A1C7D4Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraurantiacibacter namhicola|TrEMBL
MSDDFAFDEYGANPGDPLPMREGYSSHGRFERVLRSGHFAITSEIAPPDSADPDEVLNRA
SLFDGYVDAINATDGSGANCHMSSLGVCALLTRVGYSPIIQISCRDRNRIAIQGDVLGAA
ALGVCSVLCLSGDDVSVGDHPEAKPVFDLDSVSLLQTIRTLRDDEHFLSGRKLDEGPRLF
LGASINPFAPPIANRVDQFAKKVAAGAQFVQSQYCFDVDMAREFMKRAVDMGLAEQCYTL
MGVGVLASAKTAMWLRSAIPGVHIPDALVRRLEQAEKPREEGRAIAVELMQQLAEIEGIN
GIHLMAYKQEQFVGEIVTHSGVLGGRKPWALAGAEDALQTNIEHQFQAAQG
>A0A2D9X2J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MIYLELVPRNLEQLCTDSKLYLDSFSDLTGINIPDIKRLPIRSTKAANALLEHQMTVIPH
IRTQDAALDDHLSMISRLYQHGLRHVLLISGDPDDTTMSYDVTPPILTKHLKQSFSDLII
YCGIDPYRQSFDEECRYTYEKLAAGADGLFSQPFFDVSLLETFLKSFSSTQFFCGISPVT
SQRSLEYWQTINRVCFPQSFDLSLAYNVSLAKDLLACSQHYNQHAYLMPIRTPVKEYLKS
VFT
>A0A538C1Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSLTAVTSAEISLPTEADGARVSDRIAVLADTVDAVGLTDNHAGQPRMSPLAAVALAREQ
GVGTIVHVSCRDRNRLALQSQVVGSAALGAEAVLCMQGDPVPGIEHVADMTATQLIASAS
GWSAPHQLAVGAVVNPFAEDVDRELRLLRRKIAAGATFVQSQMIFDLRRLEAFLSAAEDT
LAGVRFYASVALLRSAHMAERACALPGVAIPQRAVAQISRGGGIDLAGELAAGLASISRV
DALHIFPLGAEAATREVAAEFRVARGVSAQRPAGTGP
>A0A4P5S1Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTRISALLQAGRTFSFEFFPPKNDEAQVALTRAIIELEPLAPSFVSVTYGAGGSTRERTR
DLVVQMRRETKIPPMAHLTCVGHTRAEIQDIIGAYVEAGVENVLALAGDLPADGTDIPPS
DYVYATDLVEHLRSITDMCIGVAAHPEGHPRSLDRATDRRHMAAKLQMADFATTQFFFEV
EHYVRLVNELADLGCTKPVIPGIMPVTNLSQVQRMAAMSGTEFPSWLHDELASMRTPEDV
RRAGVDAATRLCAELLEANAPGLHFYTMNRSTATREIYAELGLPVT
>A0A1M5WWN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leeuwenhoekiella palythoae|TrEMBL
MKITDHIKNANGKTLFSFELIPPRKGKSIQELYNNIDPLMEFKPPFIDVTTSREEFVYIE
KDGLLDKKVTRMRPGTIGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIHNL
MALRGDAMREEQYFKPTPGGHEYALGLVEQIAEMNKGRYLNGMVETSDCSDFCIGVAGYP
EKHLEAPSLKTDLKRLKQKVEAGAEYVVTQMFFDNKKYFEFVDLVRAEGIDIPIIPGIKP
IAVKRHLQLLPQVFKIDLPQELIDAVEACKTNTDVRQVGIEWAIQQSKELMDGGAPVLHY
YSMGKSDNIKAIASELF
>A0A3A9EIF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acutalibacter sp. 1XD8-33|TrEMBL
MKIRDLLKEENKITFSCEIFPPKKEGNFNEVFQVVDRISAMGVDFISVTYGAGGSTSKKT
TEVASYIQNQCRTTALAHLTCIDSTQRHIHDHLEGLKNCGIENIMALRGDKPVDFAGPGQ
YSHAIELIRDIRRNGDFCIGGACYPEGHVECSHKKEDLLYLKEKVDAGVDFLTTQMFFDN
NLFYNFLYRALAVGIRVPIIPGIMPIINAKQVKRSAELSGAAMPARFLAIADKFSDNPQA
MEQAGVAYATDQIVDLIANGVKHIHLYTMNRPTTAEKILHNLDHILR
>A0A6B3W777|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenzhouxiangella sp. XN201|TrEMBL
MNNPQLSFEFFPPKNEKQQETFERTRDRLAALKPAYMSVTFGAGGSTRDRTRDTVLGIRE
ATGVEAAPHISCMSEDIDSIRDLLDRYRDAGIGRLVVLRGDRPSGGGTGVFDHAVDLVRF
IREHYGDRFHIEVACYPEHHPESPTPRADLEHFRAKVEAGANGAITQYFFNPESYFRFVD
EVRAEGVEIPVVPGIMPITNYSGLARFSRMCGAEIPLWIAKRISAWEEDGDLDSLREFGE
DVVSDLCRRLLEGGAPGLHFYTLNRSRACLALCRNLGLGTH
>A0A0C2P422|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio renipiscarius|TrEMBL
MGYTHASHIDALNQNVAELSDDINVSFEFFPPSSEKMEETLWNSVHRLKALKPKFVSVTY
GANSGERDRTHSIIKEIKSETGLIAAPHLTCIDASREELIQIADDYWSNGIESIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFNQAARFAAQNHVKVPGWMAKQFQ
GLDDDPTTRQLVGASQALDMVRILSREGVKDFHFYTLNRAEMTYAMCHTLGVRPKA
>A0A371B1P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingorhabdus pulchriflava|TrEMBL
MILSLDQMAESRRALASSLFAGLPGDAEISFEFFPPKTEKMEEQLWDSIVTLAPLAPRFV
SVTYGAGGSTRERTHNTVARIAKETSIPAAAHLTCVDATREEIAEVANAYWEAGVRHIVA
LRGDPPNAGGKFEPHPNGYASAAELVEGLRKLHPFEISVSAYPEIHPEAATAQSDIDFLK
RKLDAGASRAITQFFFEPETFFRFRDAVAAAGIEAEIVPGIMPVSNFAAIQRMSKMTGTA
IPEWMAHLFEGLDDHPSARQLVAATISAEMCRRLYAGGVRQFHFYTLNRAELSYAICHLL
GKRPVETAKEAAA
>A0A8B3LB17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1A.F.Ca.IN.020.04.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARYEVDAVIQEFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A8C7N0D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus kisutch|TrEMBL
MVNNVQRVDDTWRTCTKSNSSGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEADSYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIR
NYGIEQTVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYKVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMMDELDKVN
RRGVLTINSQPTINGKPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPDEQPTEQP
VEQPAEESPVEDQSPK
>A0A8G1VXV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus fijiensis CBS 313.89|TrEMBL
MHIKEKLSQNEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPVEKVDAALQAAYKAGCTNILALRGDPPREKEN
WEATDGGFRYAKDLVKHIREKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDNFIDWVKKCRNKGVAVPIIPGIMPIQTYAAFIRRSEWTKTRIPPEWLEAL
EPVKNDDAAVRNIGKRLVADMCRRLLESGLNHLHFYTMNLAQSTQLVLEDLNLLPSEETP
LQRALPWRPSLGLNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGQPKSIRDITHIFVDFLEGKLARLPWSDSPITAEANAIKDDLVE
LNKKGIFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLIPSYLLDDLIARIEKNG
YLTYHAVSKNGNLRTNTNDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGEDWA
KCHDAFSPSRKLIQSVVDDWSLVNIVNNDFHNTSSLFDLFKDLTVKDLDTEIAVEDGETK
VHQNGVANGVEATNGTVVNGTTTELPVKN
>A0A844NAZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zobellia laminariae|TrEMBL
MKITDHIKNAKGKTLFSFEIIPPVKGHQIQQLYDNIDPLMEFNPPFIDVTTSREEYVYLE
RDGLLDKKLTRMRPGTVGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNI
MALRGDAMKDEKYFQPTKGGHAFAVDLVKQVHELNCGNYLHDTVDSDNCADFCIGVAGYP
EKHLESPSLQSDLRRLKEKVDAGADYVVTQMFFDNQKYFEFVDAAKQIGITIPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVDNCSSNKDVRKVGVEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAEQLF
>A0A1V3D5R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMSAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KKAKSFLIKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQTGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKTLEELWNSLWQVT
SGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSAVAK
VLIKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>G2G1P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp. OT|TrEMBL
MKNAVDLKSKLATGDFIYTTELGAIDGTLLEDRLTLAQDYEGLDAINVHDCPNANLRMNS
VMAASILKQQLGIETIPHFTCRDRSLLGTQADLLGAHALGIRGILATTGDAPNHGPYKGS
KGVYNYNSFELIKLINNLNSGKDANEIEIKGCTDFTIAATATPGATNLTVEIERMKRKIE
MGADFFQTQPIYDVAKAREFLAEAKMLGKPILLGVMPLINLKLVKFINNKMAGVTVPDEI
IKQMEEGKSGLEIAFEFITEFFREIQGIHIYGMGDVQMTNKIIAFAKNLR
>A0A0K1FEI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp. oral taxon 478|TrEMBL
MADIREHLKHEPLVFDGGMGTYYAQKTNTRGKGVELANLQSPDVVAGIHTEYLHAGAQAI
KTNTFAANRIVYQGDDELVAQIIRVGWALAARAAEPFGAYVFADIGPVIGLPPRDIAAEY
RFLADTFLSCGATHFLFETNSSAEGLTETAAYIKAACPHAFVQISFTALPGGYTRDGFFA
EDLVRAVAESGQIDAVGFNCVNGVRQMKELLHHLKSVSLPLALMPNAGHPMVVDGRTFYE
SAPEYFAETLAALVQDGVSILGGCCGTTPVHIRALCTALGTQGTVTADVQAAAEQEPVIQ
AESPFFAALRDGRKVIAVELDPPETGHAEKFLRGARELREAGVDAVTIADNPVARARMDA
AMLAARVHRELGIEPIPHMTCRDRNLNAIKSILLGLSAEGIHNMIAITGDPIPTAERDEV
KSVYQFNSRKLSAFIKSLGEHGDVLPFHVFGALNINAKHFPSQIGLAKKKLEAGMTGFFT
QPVLSERAKENLRTAREELGDALIMGGLMPVVSERNARFMESEIAGIHVEERIINAYHGL
DREAAEELAVRLSLEIAHDIEPYIDGYYIITPFSRTPLVARIVAELLK
>A0A8C7MLH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus kisutch|TrEMBL
MQHNGARVEDTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIR
NYGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVN
RRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAPKG
LSDHEKQDSIV
>A0A074WTF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium namibiae CBS 147.97|TrEMBL
MASDRIVDKIAALPEDGTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVNVTWGAGG
STSTKSLALAEMTQRQLGLTTCLHLTCTNMSRKLIDETLEQAKALGIRNILALRGDPPRS
DEYRSNELENNDEDDSNREFTWAVDLVRYIRKEYGHYFCIGVAAYPEGHSDQSHPEHQHA
NYDLPYLVEKVEAGADFLMTQLFYDIHAYQDYERLLRQHESGLFESIPIIPGLMPIQSYQ
IVKRTTKLSHANLPSEVSDRLEPIRNDDEAVKRAGVDILSEMVETLKKSPSPGPKGFHFY
TLNLEKAVAHIVERCKLIGAVNDTVAVEDDDTPVANGSTDKKAKARRRSSLANSAPQNRV
VVDKTSRSASHSSASFEAFDDEAGVPGEDPPSRADALAISEGEGALGREATWDDFPNGRW
GDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVSGDLDAIPWSEEGL
NPETATIKNELAGLIQKGWWTVASQPGVNGFRSDHEIFGWGPPSGFVFQKPFVEFFCSHE
DWARLRAKLDKDDQVTYFACNSKGDFQAADEESLNPVTWGCFTGKEIVTPTMIEAVSFRA
WAEEAFGIWTEWRHVYPPRSPSANLLRDIRDNYWLVNIIHHDFTESNGLWKMLLDA
>A0A333W9T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGKAR
DIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGFR
IGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQQI
LACVMPLSLGRANFMVKHKVAGIVITPHMLKALAEEKQAGHTDRVYLRCALQILICKHLG
FAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVKTGKEFTPEIARFSRQP
TSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENSVVAKALLKTEVLSKHSLVGC
ESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKQTEI
LKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A397V807|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gigaspora rosea|TrEMBL
MKIIDKINAHKSTDPFFSFEFFPPKTDDGLSNLYVRLKRMSVLDPLFVSFTWGAGGSTAE
RTTEMCTTAQGLFGLETCMHLTCTNVVDEILEEALNEAKNSGIQNILALRGDPPRGQDSW
TPSDGNFVRAIDLVKCIRKKYNDWFCIGVAGYPEGHPDSDDKAQDLRYLKEKVDAGADFI
ITQLFYDVDSFVEWEKECRKIGITVPIIPGIMPIQGYNSFRRVTNLCKINIPTDILNALE
QIKHDDQAVKDYGVSLAISMITILHEKHNVKGFHFCTLNLEKSVRLILEKMGFVPTEEER
NLRRSIKRRPIPAAKPIIWKEQSEDYLGRSDDWDNFPNGRWGNSKSPAFGELDVYGMSLR
ISKDQALEYWGEPKTLDDIIQIFKSYILCEIPVFPWSEDPISKETDVIRSNLIKLNEFGY
LTVSSQPAVNGVKSDDKDFGWGPKGGYIYQKFFVEFFVNQEKFDKLIQIIDENCWITYYA
AKRSHAFKTNIKEETSTAVTWGVFPGKEIVQPTIIEEVSFKAWKEVAFELCSEWERLYPK
DSTTQKLLKEIGDNWWLVNLVYNDYVNPEGVWEIFFGIE
>A0A2W4TYS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MGLPVSFEFFPPKTPEGVEKLRAVRQQLYPLKPEFCSVTYGAGGSTQEGTFNTVRDILAE
SVPAASHFSCIGATKASVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLVSFI
RSETGDDFHIEVAAYPEVHPQAKSPESDLQAYVTKVRAGAHSAITQYFYNSDAYFRFVDD
AYKLGADVPVVPGIMPITSSTQLMRFSDASGAEIPRWIRLRLQAFGDDTASIKAFGLDVV
TDLCDQLRNGGVPALHFYTMNQSVATLEIAKRLQLS
>A0A1V4RLZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium 4484_181|TrEMBL
MNQQKSFKAGSRLEKVLLSGHFAVTAELGPPKSADLELVRRKIGYLKSYVDAANITDNQT
AIVRLSSIATATVLCQNGLEPVIQMTCRDRNRIAIQSDILGAYALGIKNILCLTGDHQSL
GNHPGARGVFDLDSIQLVQMLKVMRDEKRFLCGEEIRNSPKAPVVEPRMFIGAAANPFGD
PFELRVVRLAKKIAAGADFIQTQCIYDMKRFRQWMQQVQDKGLHQKVHILAGLTPLRSVR
MAQYMKQSVAGVTIPDEIIQRMAQAKDPAEEGVKICVEQIEELKEIEGIAGIHLMAVAWE
KIVPVIVERAGLMPRPSV
>N1RSJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. cubense (strain race 4)|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGFTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHADYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDDVKGDDERVKMVGVDIVSELIDKIKTIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>Q2JUX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. (strain JA-3-3Ab)|TrEMBL
MALTCPPPSRFAQAIQRGEFLLTAEITPPKGSDTSTLLSLAQQLKGRVHAVNITDSNRAM
ARMSPLAASLLLQQAGVEPILQLACRDRNRLALQGDLLGASALGLRNVLALTGDPIQVGD
CPDARPVFDLESVRLLQLIQRLNNGLDCNGKPLPDGGTCLFPGAAVEPQSPSFSGLERRF
HRKLENGAQFFQSQMVTDFEQLERFMDKLGRPAGKPILAGIFLLKSAKNALFINRNLPGV
QIPDAIIQRLADAPDPLEEGIRIAAEQVRQARQICHGVHLMAVKAEHLIPHILDEAGIPP
LSS
>A0A517QGH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia panareensis|TrEMBL
MRISEIYRSGTFGLSVEIFPPKSESGDAELFRTLEDLIRYQPAFVSCTYGAGGSTSKRTI
ELCDIIQKQLQTTATAHFTCVGSTREQLLAWLQEAADVGITNIMALRGDPPKGAETFVPA
DGGLKYASELVTLIRENFPDMGIGVAGYPEVHPEALTPQADLENLKRKIDAGGDAVYTQL
FFNNEHFYRFRERCGQAGIDCPIIPGIMPITEFRRIQRIMSMCSSEFPADLVNRLEAAQD
DLDDQFEIGVEYAINQCQELIDSGVPGMHFYVLNRSQACKRIFDALGWHEDQA
>A0A8C4AFH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denticeps clupeoides|TrEMBL
AVPAPPSCKSDSSGASNSGESSRESSRCSTPGPDADRADRLREKMRRRIESGDPWFSLEF
FPPRTSSGAVNLISRFDRMGFGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLES
ILHLTCCNQTKENITAHLSKAKRLGLKNIMALRGDPLGDSWEEEEGGFSYATDLVKHIRC
EFDDYFDICVAGYPTGHPEADGYHADLKHLKEKVDAGADFVITQLFFRAETFLSFVKDCR
AIGITCPILPGVFPIQGYQSLRQLVKLSKLEVPKEIMEVIEPIKDNDAAIRNYGIQQAVE
MCKVLLDSGVVPGLHFFTLNREVATIQVLRQLGLWIEDPRRPLPWAISAHPKRKVEDVRP
IFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKCSKDALLQMWGEE
LTSEESVFEVFTNYITAQANLSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGILTINS
QPNINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLRKYEPRVNYHIVNVQ
GKNLTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEEESP
SRMIIQYIHDNYYLVNLVDNDFPLDNCLWQVIDDMFDLLDAPPEPLQ
>A0A850XHK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piaya cayana|TrEMBL
MVNETQHTCSISSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNSPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A5Y1WUD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEIFPPRRDENIKNLNVILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEIEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALVGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>H5SJB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Acetothermia bacterium|TrEMBL
MESNLQRALESKRFVVTAECGPPKSADRKVIEEKAKLLKDWVDAANVTDNQTAVTRMSSL
AACAILKSVGLDPVFQITCRDRNRIALQSDILGAYALGIRNVLCLTGDHQSFGNHPQAKG
VFDLDSVHLLETVKKMRDEGRFLSGDELTGERPAMFLGAVENPFAPPYEFRALRLKKKVE
AGAQFIQTQIVYNIPRFREFMARAGDLGLLDRVYILAGVSPIKTPGAAKYMRDNVPGLDV
PNEIVARMEAAGKGIEDKKARAEAWRQEGIKICVEIMQQLKEIPGVAGVHIMAIEWEEAV
PQIVKQAGLKS
>A0A559QHU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium 2753L.S.0a.02|TrEMBL
MSDEPISLSFEFFPPKTDTGREKLKGVRAELNELKPDFFSVTYGAGGSTRDNTKGIVKAM
RGEGLSVAPHLSFGGDTEETMIAMINEYKEAGVDRIVALRGDMPSGMGAAMQLVYANELV
AFIRQHFGEDFHLSVAAYPEIHPEAKSYRDDVRYLKGKFEAGANSAITQYFYNPDAYFYF
IEECGKEGIDAPIYPGIMPITNFQNLARFSDACGAEIPRWIRKRLNDYGDNQHALMSFTT
DLVTELCETLLDNGAPGLHFYTMNQVEPTRTIVNNLGFSD
>A0A383SST7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. juglandis|TrEMBL
MTTNARQDRLTHPHTPRLASTITDAYSLEVSATAIAGLSAAAPAIMRGATIAIPYLPNQD
DAARLAAACMVRKLGFAPMPHLSARRIGSRDALHAFVRRAVDEAGVERCLVIAGDPPSPI
GPFPDSVSLIDTGVFERCGIRTIAVAGHPEGHPGMPASERWDVLKRKCRSIAERGMAPLI
VTQFAFDADLVLTWLHALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACTAMLSKYG
ISLGKLLGTAGPDRFVDRLATGLTGAHGEVSLHFFPFGGIAQTVAWVEQYRARTAPHRAD
>A0A350Y7Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium UBA11370|TrEMBL
MTNSFRASAQSGEFLITAEVMPPKGGDPTHMIEMAKILKGRVHAVNITDGSRAVLRMCPV
AASAILLQHGIEPICQIACRDRNQIGLQADLMGAHALGIRNILALTGDPVKAGDHPEAKS
VFDLESVRLLKLIGKLNRGVDANDKPLTDGVTDLFPGAAVDPQLKSWSGLQRRFEHKLEA
GAEFFQSQLISDFERLEKFMNQIASGTDKPILAGIFLIKSAKNAQFLNKYVPGVNIPQAI
IDRLAAADNPLREGMKIAAEQVQLAKQLCQGVHMMAVKREDLIPEILDLAGILPITC
>A0A139XGH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scytonema hofmannii PCC 7110|TrEMBL
MDNILKTTPLSSFRAAALAGEFLVTAEVAPPKGGDPTHMLEMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQNGIEPICQIACRDRNRIGLQADLMGAHALGIHNILALTGDPVKA
GDHPEAKGVFDLESIRLLQIIQKLNHGVDCNEQPLTDGALNLFPGAAVDPQCKSWSGLQS
RFERKLEAGAQFFQSQLITDFERLEKFMDQIGGGCNKPILAGIFLLKSAKNAQFINRCVP
GVNIPEDIIDRLAKAKKPLEEGMKIAAEQVQIARQLCHGVHMMAVKREDLIPQILDLAGV
APVGSVVS
>A0A2S8R9L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetivibrio saccincola|TrEMBL
MKICELFQMKKVFSFEVFPPRRIDSVSIIYDTIEKLKGLNPDFISVTYSAGGSESNTDTF
KIASAIKNNYGIESVAHLPSINHTKGEVLKMLEDLRTAGIENILALRGDVNPSFSPKNDF
KFASDLISFIKEHGDFNIIAACYPEGHFESPSIIDDIRNLKRKVDAGANQLITQLFFDNN
YFYSFMERAAIAGINIPIEAGIMPVVNKKQIERIVALCRVNLPKKFLAIMNRYENNPEAL
RDAGIAYAVDQIIDLIAQGVDGIHLYTMNNPYIAHRIYEAINTLLVA
>A0A239DNB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Luteovulum] sphaeroides subsp. megalophilum|TrEMBL
MARPRISFEFFPPQTLEASFRLWETAQMLAPLKPDFVSVTYGAGGTTRKLTHDAVETIHT
HYKLNVAAHLTCVDATKAETLEIAASYAEAGVTEIVALRGDAPKGVDRFTPHPDGFASSV
ELVEALAATGRFKLRVGAYPEPHPDSADTLADVRWLKRKIEAGATSAITQFFFEAETFLR
FRDLCAKEGITAPIIPGILPIENWSGVKKFAARCGAQVPGWLDDAFDHARRDGREELFSV
ALCTELCDRLLSEGVEDLHFYTLNRPTLTREVCHALGILPEVALQNVA
>A0A2K3V178|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus koreensis|TrEMBL
MTRISVELVPRSRSGLRAELAEVAEHLSTVDTVNVPDLTRYSLRSWLGCSFARPRHRAVP
HLRAVDYNPREPLPMLESLDTHGIDEVLVVTGDAPADMSAKVYDQDAVDMIRRLTREAPH
LRVYAGLDPYRQSFARERDYLERKLDAGACGFFTQPFFDLRLMDAWADLLPDSTEVWWGA
TTVLTESSLNYWRARNHAVFPRSFEPTLDWNRGFAAQALAFARERDQHAYFMPVKANVLE
YLGGIL
>A0A3R9TRJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC05858|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRADLRNVIGQYADAGIRNMLALR
GDPPGDPTGEWVRHPDGLNYAVELVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATEVCARLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>W5QAT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ovis aries|TrEMBL
MDRPKPKVFPVGHCCPSLGMRALEAGSGRLSVPPSISRISAMAGSQGPRWEGSSSGSESS
KDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRFDRMGAG
GPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITGHLHKAK
QLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKGHPEGES
FEADLKHLKEKVAAGADFIITQLFFEADTFFRFVKACSEIGITCPILPGIFPIQGYHSLR
QLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNRE
VATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPN
GRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLSGEPNQN
GYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGWGPSGGY
VFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPG
REIIQPTVVDPVSFMFWKVRGPGAGLPCPPPEPWAGSVARSWVGGWRPHPRGWQHPDSDS
RCITSCLGRGVVLAVGYAEFLEYVLLGSSRSPWVAEHGAPA
>A0A7S1XA40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetraselmis chuii|TrEMBL
PGIMPIMTYGGFKRMTGFCKTYVPQEILDTLEPIKDNEQAVKNYGIHLGTEMCKKLLDAG
TPGLHMYTLNLDNAAVSILKNLGFINPEVLPRTLPWRPSANLTRKPQEGVRPIFWANRRH
SYLARTAGWESYPSGRWASCALRGKGGQFGAIDEKLMSKALSSEKRREKAMAAWGKTVTS
VDAVKAVFVKYVTGEIKQLPWTESDQMQSESVDICGKLVDVINKGYLTINSQPRVNGLPS
SDAKVGWGSDDGFVYQKAYMEFFCSPAALETVLSAVKAVPSIAYQAVNAKGEYQSNMAED
TVIAATWGVFPNQEIVQPTVVDVAAFKVWKD
>M1WJ66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio piezophilus (strain DSM 21447 / JCM 15486 / C1TLV30)|TrEMBL
MRVCDLIERKRPFISLEFFPPKEKDAWPGFFDVVEKLKELKPLFASVTYGAGGGTQDNTL
EIATRMKRDHGIEPITHLTSVGASAEKLDAFLRNLRDANIENVLALRGDPPAGVPDFDFN
AQEFKHATDVIEFIRERYPEICVGGAAYPEPHPESSTIQSDLDMVDLKVKKGAKFLVTQL
FFDNRLYFDYVERLKLMGSDVPVIPGVLPIMSLRSAKFILGLCGAAIPGKFLSALEKAHT
EGGDDAVYALGMEYAVKQARELVDGGAPGVHLYTLNRAEACLEIGRKLNF
>A0A1D2X000|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. A14|TrEMBL
MLFNFREKLNSSKFLVTAEVSPPKGTKFSVSLEDARQLKGIADAINVTDNQCSIMHMSSL
AFSKLLLDDGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICVMTGDFPSCGDHPGSKP
VYDLDSVQLLQLIRKLDSGINFAGNQLNGGTSFCTGAVSGIDPEKPLQLIKLEKKVRCGA
DFIQTQAVYDVGMFEEFTEAIGHLEVPVIAGLIPLKSLGMAEFMNKNISGIHVPEEIMLR
IKDAPDPVEEGLSIASETIKELMKLSRGVHIMPIGSHKNTARLLSMAGISGK
>A0A165YQ71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeribacillus pallidus|TrEMBL
MGLLQDLQNHILIADGAMGTLLYSFGIDRCFDELNVSKPEEIERIHSAYLDAGATVIQTN
TYGANRIKLARYGLEDDIKIINQKGIELAKRALQKAENKGYVIGTIGGIRSFQKSAFTLS
DIAENFREQLHVLLSENVDGIILETYYDLEELKTVLQIARKETDLPIITNVSLHEQGVFQ
NGTRLADGLKMLEELGADIVGLNCRLGPYHMLQSLEEVPLFEHAFLSAFPNGSLPRYENG
RLVYESDEHYFYEAALQFRKQGVRLLGGCCGTAPKHIRAMAEAVSNLPPVTEKEVKERNV
PIHVLPMKESQETPLPDIAKNRRSVIVELDPPKTLGLEKFLTGAKALKKAGIDAITLADN
SLATPRISNVACANIVKSRFQLRPLVHLTCRDRNLIGIQSHLMGLHTLGLHDILAVTGDP
SKIGDFPGATSVYDLSSFDLISLIKQFNEGLSYSGKSLGQKTNFTVAAAFNPNVRHLDRA
VQRLEKKISCGADYFITQPLYSEKLIEEVYEATKHLNVPIYLGIMPLISSRNAEFIHNEV
PGIKLSDSIREQMQKAGNDKEKGKREGLAIAKSLIDAAFDLFNGIYLITPFLHYEMTVEL
TEYIHEKEKAKRERKISHV
>F0IRG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis SK160|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLQIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A316F3W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus plantarum|TrEMBL
MTDRYYSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIDAAPHLSCVGSSRDSIRQILKTYRDAGIRHIVALRGDLPSGMGEIGEFRYANELVGF
IREETGDWFHIEVAAYPEYHPQARSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRAQGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLEGFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNTAGATKAIWERLKL
>A0A525VUD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. CG24C|TrEMBL
MSREPRRLREVLDQGQFAVTIEYNPPKGTNISSVLENAKQLVGRVHGVNVTDNTAAVVRA
GSLSVCRLLYELGHDPVMQMTCRDRNRIGIQSDLMGASMLGIQNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGRDMAGNKLDGSTAFTIGAAVTPEADPLGPMLAKFEVKV
KAGAQFFQTQAIYHPEQFASFMKAVRPFKSKVLAGILVLRNAKMAEFMNANIPGVSVPQE
MIDELKAAGPERAEDVGVDIAVRTIKAVRPYCDGVHIMAIKATHRLADILTKSEVG
>A0A1I7K597|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp. YR568|TrEMBL
MNLPISFEFFPPKTPEGAEKLRVTRQALYAHKPEFCSVTFGAGGSTQDGTFGTVKEILTE
GVAAACHFSCVGATKATVREQLATLRAMGVKRLVALRGDLPSGYGAGGEFHYASDLVAFI
REETGDAFHIEVAAYPEIHPQARSADADLQAFVKKVNAGANSAITQYFFNPDAYFRFVDD
AQALGVDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVI
TGLCEQLYAAGVPGIHFYTMNQAAATTEIIRRLNRA
>A0A0A0C0R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas bogoriensis 69B4 = DSM 16987|TrEMBL
MGVAALLHDAAPTVSIEVYPPRSPAGERSLKRTLDHLVERVDFVSVTHGAAGSARETTRE
VVRDVLARGEVPVVAHLTCLGAGARALRREVGGLLDDGVRDLLALRGDTHEGPPDPDGLQ
RADQLVTLLRRIEEERFDRRVLSIGVAAAPGGLRHVPDPWAYGDLQALRAKRAAGADLGF
TQVFFDVEDYTRYVDSARELGVDIPVVAGLVPLTDPRRLRRLEELTGVPVPARVLDVLDR
ETDDARRHAAGTAMGTELVEQVLAAGAPGVHLYTFNQHAAAGDLVDVVRVAPAAR
>A0A1E5NK83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira hampsonii|TrEMBL
MNNNVENFITKLENKDECAFTLEISPQAKYDLAYIKDKIDNSAISDYIDAFVVTDSPFAN
LKISSILAALQLQQRLNNNKPFITTQTMRDRNSIALQNDLIGANYFDIRMVLAVTGDAIA
NGNQKQAKAVFEGNSELLINIIKDLNKGKSLGEFAFKEPLKHIYPFCVINSYAKNNDTLK
LRLAKKANSGVKAIFTQPIYEAERLELFLKWIDELPLKEKPILVPGFFPVLSYKTAYFIY
YKLPGAYIPETWLNKLKEASDKSPEEEKKAAVELSTNLFKSMIKKHKKMHIMSMNNYDFV
VELLKSI
>E1YCH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MLHTCQKLAHIKRWRPAKVRKGGACHMNDIKSGSNLEKVLKSGNFAFTGECGPPKGANVV
HLKEKLAFLKGNVDAVNITDNQTAVVRMSSWAASAIAVQEGVEPNFQMVCRDRNRLAMMS
DVLGAYSMGIRNMLCLSGDHQIFGNHPEAKNVYDIDSMQLINLVKTMRDEEQFLNGEPID
VSPKMFIGAASNPFADPFEFRVYRLAKKINAGADFIQTQCIYNMKKFRQFMKMAVDMGLC
EKCYILAGVTPLKSVGMAQYMAKQVPGMDVPPEIIERLRGAGKGKFAEEGIKIAIEQIEE
FKQMEGVAGVHLMAIEWEHKVAEIAQRAGMLPRPEIS
>A0A2A3JEV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ag82_O1-15|TrEMBL
MLATGKATYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSVTYGAGGSTRAGTVKETEQ
IVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVPHPRGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSAEWDVDVAHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVVAAGCTTPVIPEVMPVTSVKMLERLPKLSNASFPDVLKERILTAKDDPAAV
RSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGLHHPQQA
>E1YLR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MVCRQSRRTPESCKGGCAVMNCKTPSKLEKILAAGHFAVTSECGPPRGSDISHIEHKANL
IKNHVDAINITDNQTSVTRLCSLAACIKLKLMGLEPVLQMVTRDRNRIAIQSDILGAASF
DIFNLLCLSGDHQSFGDCAQGQNVHDLDSMQLIQTARHMRDEGKFLGGADIERPPKMFVG
AAANPFADPFEIRVPRLAKKIAAGVEFIQTQCIYNLDKFELWMKMARDRGLHEKVYILAG
LTPLKSAGMAKYMKNRVPGMDVPDEVVKRMSDTPKDKQPDEGIKICIESIQRLKEVEGVK
GFHIMAIEWEEKVPEIVESAGLYPRPAVD
>A0A2X2BZQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus mirabilis|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFSSSHTRDGKYTLAITGSSKYLKT
>E5XMP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Segniliparus rugosus (strain ATCC BAA-974 / DSM 45345 / CCUG 50838 / CIP 108380 / JCM 13579 / CDC 945)|TrEMBL
MVDEWQRIKQTRTPFSVEFYPPRNDAEEAALWRAARVFERFGAAFATVTYGAGGKTREKT
VRLTGQLAKETTLPVVGHLTIVDHTLDDLRSIIAGFADQGVHNILALRGDPPGDDPFAEW
VKHPDGLEYAEDLVRLVRSLGNFHVGVASFPRGHYRAVDLEHDTKYLVQKLRAGAEYSIT
QIFFDIEDYLRLRDRVSAYDPEQGRKPIIPGIMTITSLKTLRRVVFLSGETIPSALEERL
AKAAGGGEQEDRKAVRDIGIELATEMCQRLVSEGVDCLHFNTMNFSKATVEVLTNLGYTF
KA
>Q57C59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella abortus biovar 1 (strain 9-941)|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A7K6IUS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Machaerirhynchus nigripectus|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKVHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6L8G971|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boseongicola sp. SB0673_bin_14|TrEMBL
MPLPNLSFEFFPPKGIRASCRLWEAVSELAPLDPDFISVTFGAGGAQCDLTLDTVMTIME
QFDLAVAAHLTCCNATREETLAVAESYSAAGVREIVALRGDPPSGTDTFRPHPDGFKDSC
ELISALGGLNRFRIRASAYPDPHPEAPSPHADVEWLKRKVDAGASSAITQFFFEAESYFR
FRDACDAARIDVPIIPGILPIEDWTRMKNFAKRCGAHVPAWLADAFETALRDDRHDLLAI
SVCTELCSDLMEGGVENLHFYTLNKPYLTREVIRALRTARTTASLRHVA
>A0A2C6W5Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc linckia z16|TrEMBL
MSNDMHHTHSPTAFRRAVQAGEFLVTAEVAPPKGGDPTHMIKMAATLKGRVHAVNITDGS
RAVLRMSSLVASLILLQNGVEPICQIACRDRNRIGLQADLMGAHALGIHNILALTGDPVK
AGDHSEAKAVFDLEAVRLLQIIRKMNQGVDCNDKPLTDGALDLFPGAAVDPQCKSWSGLQ
SRFERKIEAGAQFFQSQLITDFERLEKFMDTIATGYKKPILAGIFLLKSAKNAHFINKCV
PGVNIPQHIIDRLAKAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLISPILDLAG
VATVNQLVAR
>A0A0B5KBN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas plecoglossicida|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSTERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSRQATPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPMWATRLGSQVLHKVEHAVKHPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTALLTERLIPCIELETRHRSSWPQWFQAQRP
RQLSPQPAPRTQPES
>A0A8G1PWC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea ananas|TrEMBL
MSFFHANQREALNQSLAELNGRINVSFEFFPPRTSEMEETLWNSIHRLSSLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELQAIAQDYWNNGIRHIVALRGD
LPPNSGKPEMYGSDLVALLKEVGDFDITVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNAMFA
GLDEDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGIAA
>A0A7V3U3U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MATPRISFEFFPPQSLEASFRLWDTVQVLAPLNPNFVSVTYGAGGTTRDLTHDAVTTIQN
NYGLKVAAHLTCINSTRDEILAIADKYAKAGVTDIVALRGDAPKGADGFKPVEGGFTSSI
ELVETLAETGKFNIRVGAYPEPHPESPDTAADVDWLKRKIDAGASSAITQFFFEAETFFR
FRDACEKAGIDAPIIPGIMPITSWTGIKKFAAGCGASIPTWLDDAFTKAIRDGR
>B5YJV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)|TrEMBL
MSNLRKRLMSGDFVITVEITPPKGPDITGMVKKLEELKTMVDAVNFTDNPSARMRLCSLA
ACKLSMDIGFEPVLQMACRDRNRLAIQSDLLGAHALGIRNLLVMTGDHPVWGDHREAKPV
YDIDSSILVKLVGNLNSGLDINGNKLNGKTEFFCGAVVNPNAEPLMPQLKRFEQKLKMGA
EFFQTQMIFEIEKLERFIDYSKKFNTKVIAGIVLIRTKKMLHYLASKVPGVVMPSWLIDK
IERLNDEDVEKFGVDFAGSIILNLMERKLCDGVHIMAFSKVEEVKNLLDFLKIRM
>A0A7W9HU50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix ecbatanensis|TrEMBL
MTSVVERLRGDSPVFSVEFFPPRDEADETVLWRAIRELEAFDPAYVSITYGAGGSSRDRT
IRTIGRVAQETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILAVRGDPPGDPNGEWV
AHPEGLTYAEELVRLCRELGDFCVGVAAFPYGHPRSADLDEDTKYLVRKLRAGADFAIAQ
LFFEPDDFLRLRDRVAALGCDADILPGLMPLTTPRTLAKTVELSGAPMPDSFARRLNPYL
DDPAGFRKEGIDVVTEVAERLLAEGVPCLHFYTFNRSKATREIVGRLGLVPARSV
>A0A2K0XAY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella sp. DNF01162|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIANTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VYYIRSKHPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNAECLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A2A4ZPU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MHTDTQKQTPSLSFEFFPPHSIEANLRLWRSVERLAPLAPKFVSVTYGAGGATRERTMAA
IATIKDRARLNIAGHLTCVGASKKETLSVARAYAKMGVKRIVALRGDAPKGESHFTPHPD
GFASAAELVAGLKEAGDFDISVAAYPEKHPEAVSLQADIENLKRKVDAGAMQAITQFFFE
KDDFLRFRDEAVKAGINVPVIPGILPIENFAKMTRFAKMCQANVPDWMHKAFENADSQNE
TEILSTALATEMCDDLMIEGVQHLHFYTLNNPDLTYNICRGLGVSVNSFAVQNGLVA
>A0A251WKT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalinema sp. CACIAM 70d|TrEMBL
MQQSRQPLTQFRQAIDRRDFLITAEVAPPKGTNPAHMIQMASLLQGRVHAVNITDGSRAV
MRMASLVSALLLLEQGIEPVYQVACRDRNAIGLQADLLGAHALGIRNVLALTGDPVKAGD
HPDAKPVFDLESVRLLQLITKLNTGFDWVDHALTDGATDLCVGAAVDPQCGSWSGLKRRF
ERKVNAGAQFFQSQLITDFDRLETFMAEIGRPAGKPILAGIFLLKSAKNARFINRAVPGV
NIPEHIIDRLERATDPLQEGIQIAAEQVQMAQQICQGVHLMAVKREDLIPQILDRAGIAP
LQPKAPSNGQKISI
>A0A522B6T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankiales bacterium|TrEMBL
MLDSGRRLFSFEFMPGKTAEGERQLWTALRELEALRPDFVSVTYGAGGSTRDTTIDATAR
IAEETTLTPLAHLTAVDHSVADLRRILGRLLEGDVRNVLALRGDPPGDPQGEWVKHAEGL
EYAEELVRLTKSIGDFCVGVAAFPEKHPRSPDLDTDVERFVDKCRAGADFAITQMFFRAE
DYLRMRDRVAATGCEVPIIPGIMPVTNVKQITRMAELSGAVFPDDFADELHAVEDDPEAV
RRVGIDRATEMCDVLLAEGAPGLHFITMNRSTATREIWGRLGLNTS
>S7TD98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfohalovibrio alkalitolerans DSM 16529|TrEMBL
MRICDLIAQKTPFVSLEFYPPKEREQWGAFFEEAEKLKAVDPLFVSVTYGAGGGTQDNTL
EIAARLKNETGFEPLVHLTTVGATEERIAAYLRDLKTSGIENILALRGDPPRGMCDFKPD
NERFQHASDLVSFMRAGFPEFCVGVAGYPQPHPQSPTVAEDLAWTKFKIEQGAQFIVTQL
FFDVRQYVDFVGRLKAMNVDVPVIPGILPIMSLGSIRFILSLCGASIPGKFYLELEEADK
KGGAAAVSEIGLRFAIDQCRQLLDAGAPGVHLYTLNKADACLHIAGELNI
>A0A363CZ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter caeni|TrEMBL
MFETLIQKLQEDKFLTLETTPQHEPSMHNIIERIKKFKLQDRVDGFSCTDNPLAKLKYNA
LFASLKLQMEFKKPVIATMSMRDRNKIALQSDLMAANDFDVRAILALTGDPAKMSDQPHA
KGVFESNSIMLLKIIKSFNYGMDFAGRPFKIEPKQIFPFSVINSYAKNFSSLEKKMHNKI
QNGTLGIISQPIFDIDNAKKLLESFNTSKEGVEGDKQKAQLIFGLFPVTKLRTALFLSAQ
VPGIHVPQFWIDALEAAHNISEEEEYKVGMKLSSDLFKELNKLHPKIHLMTANRFDVADE
IIS
>A0A2E3PBI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTLPEISFEFFPPRDLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRDLTRDAVATLHK
HSGLTVAAHLTCVNATRDETLAIAQGFAEAGVRDIVALRGDPPKGETGFTQYPGGFADSC
ELIAALKDAGPFTIRVGAYPEAHPEAADAQADVDWLKRKIDAGASEALTQFFFDPETFFR
FRDRCEKAGIDAPIVPGILPIENWKGVRRFAERCGTSVPAALDEAFAAAERDDRQDLLAT
AICTELCSDLLDGGVDKLHFYTMNRPELTRDVCHALGVTPKASLENVA
>A0A2T7HI88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labrenzia sp. 011|TrEMBL
MSDQHPSATGRLAASTEMSPRQVVEKTELLAHIPAGTQVYVTDLGNAPEDMIVAAARTLN
ENSLVAVPHMAARRYPDFAAFERRIKRLVLEAGVTEVLAIAGEAETPGPLTSSVDLLESG
LFDRLGILKIAVAGHPEGAPDIRPEVIRSFLTRKHEIAAGSDAEFRIVTQFGFDPHRVSL
WLDELRAWGNRFPVHVGVAGPAKMTTLLKYAAFAGVENSLNFLKKRGGAVVSLMAGYDPE
TMVDPLENRLMSQPECQLAQIHVYPFGGIEKTANWLHARKSWSFCSPSSSLTVTESA
>R8TH00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VD184|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1W9MY30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium IS3|TrEMBL
MLLKSKFDQGKFIVLAEMDPPKGADISAMAENAAKVKGKADAFVVPEMNSAVMRMSALGA
AMVLQSKGMETVMQVCCRDRNRLALQADLLGAAACGIRSLMAVKGEDPRFGDHHQAKAVY
DIDRLELLQAVRMLQQGRDMAGIELAGAPVFDAVGSTVNAGAEGAVLEAELEKMHSHIAA
GATFFVTPPVFDIGAIAPFLKKADRKKVIPTVLLLKSVGMARYIDRNVPNVRIPAPMISR
IQKAGDKVRECMTIAGEIIQTLKNEGFAGVMVSTLGWEQKLPELLRSEK
>F4GJ91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerochaeta coccoides (strain ATCC BAA-1237 / DSM 17374 / SPN1)|TrEMBL
MKIREMFGEKVVFSLEVFPPRQIAPVQTIYHALEEMKDLNPSFISVTYGAGGRGTDNATI
GIASAIKHQYGIESVAHLTGFHLSREDVRLQLEKLAENGIENILALRGDIVSGIAGKGEF
TYAHELIRFIKENGDFHVMAACYPEGHPESPDIVSDILNMKEKVDAGADHLVSQLFFDNE
FFFRFRERAQLSGIKVPMEAGIMPVTNRKQIERMVSLCKVELPKKFLTIMRKYEDNPVAM
REAGIAYAVDQIVGLIAEGVEGIHLYTMNNPYIAQRIHQAVSALI
>A0A0S7ZH78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium DG_61|TrEMBL
MSKLQESLQAGKFTITGEIGPPKGVDLHHCMDEEVSFIRDRVVAINVTDNQSSVMRVCSL
SICALLARKGLEPILQITCRDRNRLGIQGDVLGAYVQGIRNILSLTGDHNTAGDHPGSKP
VFDLDSVSLLQAMTSLKNGKDLAGNDLEGVPNDLFCGAIVTPEADPVEMQLIKMERKIEA
GAQFFQTQAIYDPKVFEDFMNKASKFKVPVLCGIVIIKSAGMASYMNNFVPGVRVPEEMI
KVLKEAPKEDRAKRSIELMADFIEKVKPMCQGLHIMAMGWEKYVPEMLDMCDL
>A0A147I0X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas endophytica|TrEMBL
MTISVNQLEEARRALDAPLYADVGGKVDVSFEFSPPKTDKAEENLWQSIETLCPLGPRFL
SVTYGAGGSTRDRTHATVARIARETSVPAAAHLTCVEATREEIDAVASEYWAAGVRHIVA
LRGDPPAGAAEYTPHPGGYENAAALVAGLRRLHPFEISVAAYPEMHPNSPDQAADLDNLK
RKLDAGANRAITQFFFEAETFFRYRDAAAAAGIDAEIVPGIMPIGSFAGVQRMAAMCNTA
VPGWLVRLFEGLDDHPGARQLVAATVAAELCRKLYAGGVEQLHFYTMNKAELSFAICHLL
GVRARPQQGRAAA
>A0A6A7K2N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus|TrEMBL
MSLTALFKNKTVFSLEVVPPKKDSPKEAILPTLQQLQSINPDFISVTLRAGGSDHYTGAV
QIADLIQNQLNIPAVAHVLGLYQTREQVLNLLDNLSEINVKNILDLRGDKIPGKQPVGDF
NHANDLVAFVHQNRPDFSIASACYPNCHPEATGFVDDIAHLRTKVDAGANHLISQLFFDN
QAFYDFQEKAEIAGIHVPIEAGIMPCTNKKQIERITQITGVPLPKKFSTILDRYQNSKEA
MRDAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHR
S
>A0A5R9QT06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labilibacter sediminis|TrEMBL
MTAAELVLKNKETKFSFELLPPLKGNDIDKVFKTIDALKEFDPQFINITSHREEYAFQTN
DAGYVEKKVIRKRPGTVAVAASIQNKYGIKVIPHIISRGFTKAETEYALIDLNFLGIHDI
LVLRGDDTHKDKYPERTDDCNKYAIELAQQVNDLNNGKYLDGTSMDPIVTPFAYGVAGYP
EKHEEAPNMESDLAFLKAKVDAGAEYVMTQMFFDNQKYYDFVDKCRAIGITVPIIPGIKP
VTTANQLTVLPKIFSCEIPEAFAKELRKCKDNDQVKQVGVEWCTQQALDLKKNGVPIIHF
YTMMATASTRKVAEAVY
>A0A1V8MAY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloprofundus sedimenti|TrEMBL
MMTKENKADLFSFEFYPPKTEEGAANLEQVHRDLAKLNPDFFSVTFGAGGSTRDKTYDTV
VKIQKSEIAAAPHLSCVASTKENIRDILKNYREHGVSKIVALRGDLPSGMMSAGEFRFAN
ELVEFIRAETGDHFQIHVAGYPEIHPQAKNATEDFNNFKRKVDAGADSVITQYFYNAEAY
FYFMDKCEKNGIDIPVVPGIMPITNYSQLFRFSDMCGADIPRWMRKTLECFGDDKASIMA
FGEDVVSKLCQQLLDNGAPGLHFYTMNQSKATLAVWNNLKF
>A0A1D9EMK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. glycines str. 8ra|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A2V4EH88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus|TrEMBL
MSLTALFKNKTVFSLEVVPPKKDSPKEAILPTLQQLQSINPDFISVTLGAGGSDHYTGTV
QIADLIQNQLNIPAVAHVPGLYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDF
NHANDLVAFVHQNRPDFSIASACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDN
QAFYDFQEKAEIAGIHVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSEEA
MREAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHR
S
>A0A7X1EIZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter cronae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A8H4D6E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] haemuloni var. vulneris|TrEMBL
MATVTAKIKALEPGERFCSFEFFPPKTDAGFRNLLARLSRMMALNPLFLTVTWGAGGSTA
EKSLDLAATCQKELGVTTVLHLTCTNTNKEIIEDALKRAKEAGIRNILALRGDPPRTEEY
WTPNCDFSNAVDLVRFIRQEHGDYFCIGVAGYPEGHVEGADASAQDPKKDLPYLIEKVEA
GADYVVTQLFFDVDKFVAYEQLLQDTPQLKNIVLIPGIMPITTYRVFIRATRLSHASVPK
NILDDLDAHINDDDMVKNIGLDVVTKMISEIDSRTNGRVRGYHFYTLNLEKAVASIINRS
PVLQNMIPHNKSVQHDDAIASDSDDDLPAGTVIPAKNGRRKSSVNENQLASADAMDAKRA
LVSKALSKDPKAIVDISTGKGVLGKDATWDEFTNGRFGDSNSPAYGEIDGYGPNLKLHSN
KEVQETWGEPKSTADVTKIFVDYLSNKITVLPWADSELSPETALIQEELFELNERGWFTL
ASQPAINSCSSRDKILGWGPPNGHIFQKSFVEFFIPKKQWEEDLLPRISTQVDDKTITYY
CGDASGHISSNLPISTGKNSNTKSAVTWGVFPSKEVLQPTIIDYESFKAWNEEAFLLWLE
WARCYRKDSDSYKLLNSVYNDYYLVSLVHHDFTDEFVLWTTLLSD
>A0A4Y6KNA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azoarcus sp. DD4|TrEMBL
MHKTELSIEFFPPQTAEGAEKLRAVQARLAGLKPAFFSVTYGAGGSTRERTFSTVKEIAA
SGSEAAPHLSCIGSSRDSIRAILKEYADAGVKRIVALRGDLPSGVVDPGEFRYANELVEF
IRAETGSRFRIEVAAYPEWHPQAKSPADDLAAFKRKMDAGADSAITQYFYNLDAYLHFVD
AVRKLGIDKPVIPGIMPIASFSKLARFSDACGAEIPRWMRKKFESYGDDADSIRAFGLDV
VTELCQKLLAAGVPGLHFYSMNQAGLTTEICKRLQLA
>W9XHR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cladophialophora psammophila CBS 110553|TrEMBL
MTSEDDDRLPTLLASLPPSSYYFSLEFFPPKTSSGFSNLQARLTRMAAALRPLFVTVTWG
AGGSTATKSLELAEVCQRQIGLTTVLHLTCTNMKRHMIDEALEGAKEIGIRNILALRGDL
PREEYKDTTSADENDSGSGGSGTESNKEFAWAVDLVRYIRRKHGDYFAVGVAGYPEGHAD
ESHPEQGKQSVEHDLPYLAEKVAAGADFIMTQLTYDIEAYAAYEKRLREYTDPDGKKLFE
KIPVIPGLMPIQSYQIIKRITKLSHAKLPRKISERIERVKSDDEAVKKVGVDILSELVEE
MKTLPQPEGLPRGFHFYTLNLEKSVSFILERTGLIPLISSEGSVDGKDDDSVSDSEVVVD
DSKQDSPAVVTTGPMNSRNENGQQPTSLLRRRRSSVNAQPHNRVITDRRSDPRTQSRRPD
SDTDPPGVGPGPNLKLASQHSARDRGTGIPAASPTRRHNLLISEGQGSLGREATWDDFPN
GRWGPSHSPAFGEIDGYGPSLKVSPLMARKLWGYPRSREDVTELFRRHVLGELVGVPWSD
DIDTDLSAPNGTPTNVSQTSGALRAETDVIRSELLSLISSQNYWTLASQPAVDGAPSSDP
IFGWGPPGEGFVFQKAFVEFFCGREEWEEKLRPRLMKYGSDVVGWMKTDNEGVFESSELV
ARDQARNKKTSPVDTEKENTIPVSTPQLSNQKSATTTSPVNTVNAVTWGVFPSREILTPT
IIEAESFRAWAQEAYAIWHEWKRCFPRGSQEAGFLEKMGRENVLVNVVGQSFRGGHDGGR
GEGARLWTILLEPDDETKS
>S4IQA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis JCP7276|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIHSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKISEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A4R6GI75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herminiimonas fonticola|TrEMBL
MNQQNFSIEFFPPKTPVGVEKLRVTCAKLAELNPKYFSVTFGAGGSTQHGTLDTVLEIRG
AGHEAAPHLSCLGSSRENLRSILQEYKSHGIKRIVALRGDLPSGYGAMDASSSEFHYANE
LVEFIRAETGDWFHIEVAAYPEMHPQAKSPNDDIASYARKVKAGADSAITQYFYNADAYF
RFVDDARKAGADVPVTAGVMPITNYSQLMRFSDMCGAEIPRWIRLKLASYNDDTDSIRAF
GLDVVTDLCERLLAGGAPGLHFYTLNQAAATHAIWSRLNLSQK
>R6R4A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:424|TrEMBL
MKLSEAMKDKMLLSFELFPPKTDKGMENLPGTIEHLCKYQPAYISCTYGAGGTNVGKNMD
VCKMIQDAGTVPVTHFTCIGNTAEGIKDQLQNYLDNGVDHMLALRGDLPFGWTGTGGDFA
YATDLVAYVRKEFGDKFEIAVAGSPEGHISCRSLEADIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRCAGITMPVDVGIMPILDQAATINMALSRNACVMPRELCEIISRNWIFPN
PFVKDPFDADVEGKKERFREAGIEYTINQIDEYRACGINGIHLYALNKWKDVSEIIDRSG
LCTLV
>A0A1F8NGK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_66_10|TrEMBL
MSSIGAGAIALQEGLEPVIQMTCRDRNRLAMQSDFLGAYALGLRNVLCLTGDHQSFGNHP
TAKNVHDMDSLQLIQMAVGLRDRRCFQCGDEIKGIEPRFFVGAAANPFGDPFEWRPLRLA
KKVKAGADFIQTQLIYNIDRFAEFMAKVRELGVHQEVYLLAGIGPLKSPGMAKYMRDEVP
GLDVPNEFVDRMTAAGEGIAKEDKKARAEAFRKEGIQIAIELIRKVRQIEGVAGVHIMAI
EWEEAVRPIVEGAGLLPRPEPAPLPAEHVGAGA
>A0A4Q3ZDG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tropicimonas sp. IMCC6043|TrEMBL
MTAPHVSFEFFPPRSVEASFRLHETVQSLAPLNPDFVSVTYGAGGTTRRLTHEAVSAIHR
TTDLKVAAHLTCVDATRDETLEIARGYAAEGVTDIVALRGDPPKGATRFEPHPQGFADSC
ELVAALRETGDFTIRVGAYPDRHPEASSDTADVEWLKRKFEAGADAAITQFFFEAETFFR
FRDACAKVGIDKPILPGILPIEHWAGTKRFAERCGTKVPAWLDDAFEKAARDGREEILAI
AVATELCSELISGGVEHLHFYTLNKPHLTHDICRALGVTPDTRLQDVA
>I3XB05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium fredii (strain USDA 257)|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMEVQLFQTVADLSIFAPAFQTVTYGAGGSTKAH
SLTTVKRMIGEMGLQNTAAHLTCVGAPKTEVDAVIDEFVACGVRHFVALRGDPQGGIGSA
YQPFAGGYESSAALVKALRARGNFEISVSAYPEKHPESSDVAADIDMLKRKVDSGATRAI
TQFFFDNDDFERYLERVRRAGVHIPVVPGILPINNLTQVIRFAGLCGSKVPEAIISRLAH
LDDQPEERFKEASHIAAEQIVDLARRGVRDFHIYTMNRSPLIAAVCDLVGYARRPAKRAT
VSSYRAVATA
>G4EXZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis subsp. subtilis str. SC-8|TrEMBL
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSALEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTRAKEFIS
VHHERTEPGLDEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMAHAGEDKEKQKTEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>A0A851INK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia sp. oral taxon 417|TrEMBL
MRIKDLFEKKEHLISFEIFPPNKNFSEEKLKDVTAELVQYKPDFISVTYGAGGKTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEINDYLQEAKKCNIKNILALRGDVPQGETEDIYN
RGDYKYASELISDLRKNSEFNDLSIGGAFYPETHYENNDLVDLFHLKNKVEAGTDFLASQ
MFFDNDVFIKFKEQAEKLDIKVPLIAGIMPVTNAKQIKRIIELSKCSVPEKLDKLLEKYG
DNPESMKKAGIMYASEQIIELLAYGIRGIHIYTMNKPEIAKEIMKNIEFAR
>A0A2I0EXH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus sp. Urea-3u-39|TrEMBL
MMLLDELKKRMLTADGAMGTLLYSYGIEYCNEELNIQRPEVIEKIHRDYIAAGADIIQTN
TYGANAHKLARYGLEEQTEAINKAAIAIANKAAKDGGQFVVGTIGGIRGIRKSDATLDEI
VAMVDQQAQHLLSGNPDGLLLETYYDFEELAATVSHLKKLTDAPLIAQLSMHEPGILQNG
MSLNEGLKRLDALGAEIVGVNCRLGPHHTIQAFEGVELPEKAFLSAYPNASLLDIEDGRI
VYESEADYFGRAALLLREEGVRLIGGCCGTTPKHIEAVKKRIGHLQPITEKKVEEKKPIV
IREAEALKDKPLHEKAKTERTIIVELDTPRHLDIDKFLEGSKALDAEGIDAITMADNSLA
SPRISNMAMGSIIKRKQDVRPLAHITCRDRNLIGLQSHIMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVVERAVAR
LEKKIEAGADYFISQPVYTKEKIIEIHEATKHLDTPIFLGVMPLTSIRSADFLHNEVPGI
KLSEEALDRMRACGEDKEKATAEGIQIAKELIDTAAELFNGIYLITPFVRYDMTVELIRH
IRQLDLKKASDRAYA
>A0A8H4CW69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum gloeosporioides|TrEMBL
MDKITDKIAALPADANYFSLEFFPPKTVMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
SQKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKSE
YRTAEDSDVEDMDDFVWAIDLVKYIRKKYGDYFCIGVAAYPEGHADESHPLGQSFEHDLP
YLVDKVQAGADFIMTQLFFDIKAYDNFEKVLREHPSGAFKTIPLLPGLMPIQSYQMIKRT
TKLSHAKVPDALMARLDAAKGDDEKVKRVGVDILSELVEQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPEHADDDNESAIIDDAVGGAAEVPTVQLNGLNPMSAVPRALSNSN
RRASSIGSDPHNRVIVSSASNPAYETTAASLSAEPVNTRANTLAISEGEGVLGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHMSVTQAVGLWGTPKTVQDINNLFIRHIKGQLSAIP
WSEEELLPESNIIQQELLELNSRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKSFVE
FFLPSADWAGLVARLNEVKDKTICFYAANAAGDFVSSDSSGGLVLEGTESSTNAVTWGVF
PGKEIITPTIIEEVSFRAWAEEAFKIWGEWAKVYGKGSASEALLERIRSEYWLVNIIHHD
FVERDALWKLLSGEKEI
>A0A5M6A9E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides cellulosilyticus|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYDTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRHRPGTVAVAAAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELAYEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A1V0ADM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea sp. ATCC 55076|TrEMBL
MPFEPICEIEPPTKPDLKHVRHQIGTLSKIAHAFLIPDNHIGRATVSSVAVAHEVEAMGG
RGIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTSGNRTGDLNVRSMIEEARAF
SADFRVGAAAGLRPLPAWKRTADFLFSQVSFSVEQQLRWREAHPVDVPVYAGVMVLASER
HARTLAAAIPDIALPEELIARVAADRMAGVEAACEQVLALRDSGAFAGVHLVPVARYRDV
ESRLAGAL
>A0A1F2U9I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium RIFCSPLOWO2_02_FULL_65_29|TrEMBL
MRDVFASARAARRPVVSFEFFPTKTDEGERALLEKTIPALGQLNPDFCSVTYGAGGGTRA
KTLAIVDRIQREQRLTTMAHLTCVNATRDDTLSVLRQAEALGIKNILALRGDPPSGDSTF
TKTDGGFEYSYELVRFVREVGEFSIGVAGFPEGHVACKEGKHVDWQRLKSKIDHGADFVI
TQLFFNNDDYFEFRDYLTGLGVTVPIVPGILPILSTAQIKRFVALCGAELPRPLIEELEK
RRDDDEAVIRFGIEYATEQCEALLSAGAPGLHFYTLNKARSTTEVVKNLGL
>D3LVZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera genomosp. type_1 str. 28L|TrEMBL
MRTTDLFTQKTVFSLEVFPPKRDMPLESIYPTLQELSRLHPDFISVTCGANGQGGNRTAE
VAATIKHTYHCETVAHLPCLYLTEDDVRHTLQELKVHGIENILALRGDETPGKTPIRVFE
HAADVIRFIKEEDPSFTILGACYPEGHTEAKTLGADIRYLKQKVDAGADELISQLFFDNE
LFYRFLERCEIAAINVPIEAGIMPVTNKKQIERMVSLCGATLPVKYQRLLAKYGHSPVAM
RDAGIACAVEQIIDLLANGVDGIHVYTMNNPYIAGKIAAAIKNLI
>K8B3P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter dublinensis 582|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGAPIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVELKT
A
>A0A191ZH57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halothiobacillus sp. LS2|TrEMBL
MHIPISCEFFPPKSDEGAAKLRAIHLRLAETLKPEYFSVTYGAGGSTQERTFTTVREIQM
ASSVPAAPHLSCIGSTRAGIADILDQYRALDIRRIVALRGDLPSGMRDPGDFRYANELVA
FIREHAGDWFHIEVAAYPEFHPQAPNATADLEHFKRKVDAGANGAITQYFYSIEAYSRFV
DDCERLQIDIPIVPGLMPISNYTQLARFSDACGADLPRWLRKRLEAFGDDMDSLRAFGHD
VVVELTADLISAGAPGLHFYTMNQADSIIALCRDAGAQPSHNG
>A0A1S2DD89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinicola sp. MIT1003|TrEMBL
MMSTQPPLGISFEFFPPNTEAGREKLGGVRDALAARNPRFFSVTYGAGGSTQARTFDTVK
TVRRSGVSTAPHLSCIGSEKGALRELLQTYREDGVDSLVALRGDLPSGMGGAGELRYANE
LVEFIRAETGDHFEIAVAAYPEAHPQAPSFERDLENFARKAKAGADLAITQYFFTADAYF
HFVDRVRAMGVEIPIVPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIQAF
GTEVISNLCQRLLDGGAPGLHFYTLNQSAPTLRVLDNLAFKH
>R6UY43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides faecis CAG:32|TrEMBL
MRVIDLIHNSEKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFSREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLFWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEALKCKNDKEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A0M0SE16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hapalosiphon sp. MRB220|TrEMBL
MLIFMLDTQNPTCLTSFQTAAKAGKFLITAEVAPPKGGNPQHMLKMAATLKGRVHAVNIT
DGSRAVLRMSSVIASAILIQHGIEPICQIACRDRNRIGLQADLMGAHAIGIRNILALTGD
PVKAGDHPDCKGVFDLESVRLLQVIEKLNHGFDCNDKPLTDEALDLFPGAAVDPQCPSWS
GLQKRFERKLAAGAQFFQSQLITDFEILEKFMDKIAADCGKPILAGIFLLKSAKNAQFIN
RCVPGVNIPEHIIDRLAKAKYPLEEGMKIAAEQVQTAQQLCQGVHMMAVKREDLIPQILE
MAGVAPVNQMVLR
>N9MEP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 1847|TrEMBL
MAQNSPFLNFFIMSLFSQCLEQKQFCILVEYLCSNRDTPAVPPSLAGYQAMMTLADRVHS
DEDPAPLELAQQYAPEIEKLLHFSGKGRDIQEFERFLDQAEQHGYHNLLLLSGDKLKNHN
FGREIPAQRTRYLESVNAVMAAKQRHLFNIGVAFNPFKYTEAERDAQYLKLHKKIKAGAD
FLITQLGFDLDCLQHSQSFISQHYKQFPLIACVMPLSLKRAQFMLKHQVAGLVIPAHMVN
VLKSEYEADPVQAEANVYARCALQILICKHLGFVGAHLSACHKPQEQQKLEQFLKQYENC
SLAVCEKAWKDLWKMDSGLELKPELATFSKPVPPAQIFKYKQMHLMHQLFFASHAALGIG
RFIFKANFWNKARPDQLLLKMEHWSKHPLVGCESCGHCRLDDTLYICPETCPKGLANGPC
GGTSLDRCEFGDRECIHSVKARLAKRLDQTEVLRSKLIPAISIETRYTSSWKNWFKHSES
H
>A0A808FGD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. phaseoli var. fuscans|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A7U8IZE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella abortus bv. 4 str. 292|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A7C4DM93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiritimatiellae bacterium|TrEMBL
MSVRRPLLERIREAPLVFDGAMGAMIYQRGVFLNACYDELCLTQPQLIRDLHAEYVEAGA
EAIETNSFGANRVKLAAYGLADRVAAINRAAARLAREAAGAEVYVCGSVGPCFEAETPLD
ASAAAEMEAAWAEQIGALAEGGVDLIALETFGSLAQLRLAAAVARRTARVPVLASFRLPP
GENDAAGLRAAEEAAAALSEDDNVDWIGLNCGRGPADLLQPLRRAVARASKPVIAMPNAG
GPRQVGGRMLYLNSPEYFTEFCKRYLEVGVRGVGGCCGTTPAHIRMAARAVRGVSGARRH
VALAAAPTAADGAGAARVGKPLAEKSPFAAKLAAGRPVKSVEVLPPAGGGGLAGFLAKCR
ACREAGVDAVNLPDGPRASARLSVLATALALRREVDLEPIPHYCCRDRNLIGMQSDLLGG
FALGLKTWLFITGDPPKLGHYPDATGVFDLDAIGLARLADNLNHGFDAAGQPLDQPTAIA
IGVGVNPAAVEPERELERFFRKIDAGAEFAFTQPVFDAEALLRFLDRARGYPRQIPIVAG
LYPLLSLRNAEFMATHVPGVVVPERVLRRMAGCATKEDGLRRGIEIAREIRERVADGVAG
FQAAAPLGRIDAALAVLA
>A0A175W7M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Madurella mycetomatis|TrEMBL
MHIREMLADAERTGEPSFSFEYFPPKTAQGVQNLYERMERMYNFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYLGLEACMHLTCTDMGEDKVNDALRKAYKAGCTNILALRGDPPREKEK
WEATEGGFRYARDLVAHIRKTYGNHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGASF
IVTQMFYDVDNFLRWVEKVRARGITVPIVPGIMPIATYASFLRRANHMNCRIPEEWLAKL
EPVKNDDLAVRDIGKTLVADMCRKILAAGIRHLHFYTMNLAQATRMVLEELDWMPSAKRP
LKHALPWKQSLGFGRRGEDVRPIFWRNRNKSYIARTQDWDEFPNGRWGDSRSPAFGELDA
YGVGLTGTNEQNRKKWGEPTCVKDIANLFIRYLNKKIEYLPWSEAPVAEEADLIKKDLID
LNSRGLITVNSQPAVNGAKSTHPVHGWGPAKGYVYQKAYLEMLVSPELFPEIKRRIGSHP
DMTYHAVTRTGNLETNAESEAPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGTEW
ARCYEAGTPSRLLIEQIMDTWYLVNIVNNDFHEGQMLFELLKDLEVQDMDKVPESQSNGT
HDLTNGAEASA
>A0A2D6J3J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
DLRTLLNDYRAQGIQRIVALRGDLPSGMGHASGELRYANELVEFIRAETGDHFKLEVAAY
PESHPQAPNFETDLKNFIRKAQAGADSAITQYFFNADCYFYFVERVRKLGVETPVVPGIM
PITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQAFGVQVITEMCEKLLAGGAPGL
HFYTLNQAEPSLAIWNNLGLSR
>A0A059DCQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eucalyptus grandis|TrEMBL
MKVIEKIRESAGVCNGGGNGGEGKVVFSFEFFPPKTEDGVDNLFERMDRMVVHNPTFCDI
TWGAGGSTADLTLDIANRMQNMVCVETMMHLTCTNMPVEKIDHALTTIKSNGIQNVLALR
GDPPHGQDKFVQVQGGFACALDLVKHIRAKYGDYFGITVAGYPEGHPDVIGQDGLATLQA
YQNELAYLKSKVDAGADLIITQLFYDTDIYLKFVNDCRQVGIHCPIVPGIMPINNYKGFI
RMTGFCKTKIPAEITAALEPIKDNEEAVRNYGIHLGTEMCKKILANGIKTLHLYTLNMEK
SALAILMNLGLIEESKVSRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTMGWDQYPR
GRWGDSRSAAYGTLTDYQFMRPRARDKKLHEEWVVPLNSIEDVHEKFKKFCLGKFRSSPW
SELDGLQPETRIINEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLE
LFCSPEKLNILVEKCKGFPNLTYMAVNKGGDKWISNVGDSDVNAVTWGVFPAKEIIQPTV
VDPASFLVWKDEAFEIWSRGWACLYPEGDPTQKLLQESSYFLVSLVDNDYMKSDLFAVFE
DI
>A0A1M5DP76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas ilicicola DSM 19980|TrEMBL
MSKNEHPLGISFEFFPPNTDAGREKLMQTRDALAECKPHFFSVTYGAGGSTQARTVDTVK
QVSECGITTAPHLSCIGSDKGELRALLAMYRERGIDSLVALRGDLPSGMASIGELRYANE
LVEFIRAETGDHFEIAVAAYPESHPQAPSFDRDLENFVRKMRAGANLAITQYFFNADAYF
HFVERARALGIEAPIVPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDRESIEAF
GEEVVTRLCQRLLDGGAPGLHFYTLNQAPPSLRIVDNLA
>A0A2I0M398|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Columba livia|TrEMBL
MCVLFVPTVLLLFPSSRELTMVNETQHTCSTSSSSKSDGGSSSGSESSKDSSRCSTPVLD
ADRHERLREKMRRRLDSGDRWFSLEFFPPRTANAAVNLISRFDRMAAGGPLFVDVTWHPA
GDPASDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDITANLQKAKRLGLKNIMALRG
DPVGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDVCVAGYPKGHPEAESYEADLRHLKEKV
LAGADFIITQLFFRSETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQ
EIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGM
WNEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFG
ELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDD
PLATETNLLKEQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTS
SEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPV
SFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDD
TFELLNSPTQK
>A0A0A6STR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sacchari|TrEMBL
MKPIELSFEFFPPKTPDGIEKLRATRAQLLTLKPRFVSVTFGAGGSTQQGTLDTIVEIAK
EGVDAAPHLSCIGSSKESLREILRQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVAF
IREETGDAFHIEVAGYPEYHPQSRSPRHDLEAFAKKVKAGADSAITQYFFNGDAYFRFVE
DAKKLGVDVPIVPGIMPITNYTQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCRRLIEGGAPGLHFYTLNAAGATKAICERLDL
>R5UUW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odoribacter laneus CAG:561|TrEMBL
MKITDILNRKAKPFATFELVPPLKGSDINKLYKAIDPLMEFKPPFINITFHRNEIEFRQK
ENGTFEKITVTKRPGSVAIAAAIMKRYQLEVVPHLICGGASKYTLENDLIDLNFLDITNV
MALRGDAIPGQKYFIPEVDGHKYSCDLVSQIHNMNQGKYLDETLTNAIATNFCIGVAGYP
EKHYEAPNPETDIMNLKRKVDAGADYIVTQMFFDNNRFFHFVDKCRTAGITVPIIPGLKP
ISTHTHIEMLPRTFSIDLPEELMKEVRKCKNDQEIYQVGIEWCITQSKDLLAHGAPAIHY
YTMGKADNIRTILKQTF
>A0A519FBU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSQDRSYSFEFFPTKTDAGHEKLLATARTLASYNPSFFSCTYGAGGSTRDRTINTVLQLE
KEVHIPAAPHLSCVGDSKADLRSLLTQYREAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFH
FVERVQKLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTASIQAFG
EHVITEMCERLLHGGAPGLHFYTLNQAEPSLAVWNNLKLSA
>A0A3S2Y504|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hwanghaeella grinnelliae|TrEMBL
MTNTGTESDQIRDFLSNATFEVTPTQASKVDDFREVLAAGTTVFVTFLPGSDFAETVKTV
KKLSAEGMNPVPHLAARSIPSKAFLEENLKVLQGEAAVSEALLIGGGVDTPVGEFDATIQ
VIRTGLLEKYGITRLGVAGHPEGSPDIKDADIIAALLEKNVYAKETGTDMYITTQFCFEA
KPIIEWDKAIRDAGNELPIHIGVPGLATVKTLMKHAVACGIGNSMNFLKKQALNVTKLMT
VNAPDRLVRDLAAYHATDPNCGIDMAHMYPLGGLKKTAAWTRAVQDGKFELKTKGGFNVT
VPIE
>A0A0Q7R039|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root140|TrEMBL
MDIAARIKSGQGDFVIFAVTPPRRSTPTDRLPEIARATVERLEHLDLDGLVLYDIDDESS
RNPEERPFPFSPTVDPAEYRTEHLEQWGTPVIVYRAVGKYQREDLRSWIAEQDPRRTLSV
MVGAASSGSSPSVSLADAQAMSAALNPDLLLGGVAIPERHSRRENEHLRLIAKQEAGCRF
FVTQVVYDLNAAKNLVSDYRYECESRGLVPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLRHAANPLLASLAQATATAVELIDYCRRLGVPFGLNVESVSIRREEIEASVELAGQL
AGHLRK
>B5F0T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella agona (strain SL483)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3D2D9N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
VERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGD
>A0A7Z9HS01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium|TrEMBL
MDSQKKYSRHFSCEFFPPKTEAGAASLVKVRAELERINPDFFSVTFGAGGSTRDKTMEAV
VAIQRSGCQAAPHLSCVASTKDNIREVLSSYQEQGINKIVALRGDMPSGVLSAGEFRYAN
ELVEFIRTETGDYFDIHVAAYPEVHPQAGNAQDDLINFKRKVDAGANAAITQYFYTAEAY
FSFVDSCEKQGIDLPVVPGIMPINNYTQLSRFSEMCGAEIPRWLRKRLEVFGDDREAIQS
LGIEVVSEMCQRLLDNGAPGLHFYTMNQSVPTLRIFDNLHSR
>A0A7Z8FGI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella sonnei|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7D3X6G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp. BRD67|TrEMBL
MKVTEHLRRANGKTLFSFEVLPPRKGENIHSLFANIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRKRPGTVGICAAIKNRFDVDTVPHLICGGFAKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFQPHPDGHTYACDLISQISALNHGRYHDHDEQYQPEGSEPILCTDF
CIGTAGYPEKHFEAPNMGSDIRFLKEKIDRGADYIVTQMFFDNEEFFKFEKRCRTAGITV
PIIPGLKPLTTKSQLIGLPRAFFLSIPEALAEAIHQAKDNAAAREVGIEWCLNQSRELMA
HGVPCLHYYSMGKAESIRRVAAGLF
>G7X5I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus kawachii (strain NBRC 4308)|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSNWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHVFVDFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A836BNH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon|TrEMBL
MTIRYELNPPKVDKDGLLSKDELAKKLDKFKNRVAEISSSCDGIHITDSVLGTKRISPLT
TAEIIRNNNSNLEVTVSLRVRDKKIEEIEKLVKDAIQLGLEGILIIKGDPSTENPNNSGL
IPSKVVKHLKDSGFAEKIDLYLSLPSKPNFAKIQKKIDAKPKGFITQVIASTDQVTNIVD
ALKAHSFRIIPIVLFPSQKNLKSAEFLKLDWSNYQDNVIDFIKNVHNITGDILITSPNDF
NGVRMTLRKLEI
>A0A5B7ZS72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomonas aquatica|TrEMBL
MLPISFEFYPPKTDEQRAQLDRSVQRLKAHAPQFMSVTFGAGGSTLSHTPETVQRLRSEH
GVAGVPHLTCVGGSREEIRQLLKLYRALGCDRVVALRGDTPSGMVRSGDLRYASELVELI
RAEHGDHFHVEVAAYPETHPQAEDAHVDLRNFKTKVDAGANGAITQYFYNTDAYFRFVDD
ARALGIEVPIVPGIMPISNFSQLKRFSEACGAEIPRWIGQRMRAYGDDADSIREFAADFV
AQLCRRLVAGGAPALHFYTLNLAKPTLNVLERLR
>A0A6A6HCG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Viridothelium virens|TrEMBL
MHISQKLAEAERAKRPSFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGHLS
QLTCEMVRAAQSAYGLETCMHLTCTDMEKSKVDAALKDAYNAGCTNILALRGDPPREEEK
WEAKSEQFRYAKDLVKYIKETYGNHFDIGVAGYPEGCDDNDDSEELVEHLKEKIDAGGTF
VVTQMFYDVDNFLEWVQKCRNRGINVPIIPGIMPIHTHAAFMRRANWVRCKIPQAWTEAL
EPIKNDDAAVRDVGKGLVAEMCRQMLNNGINHLHFYTMNLAQATRMVLEELKIVPDAQTP
LEKPLPWRQSLGLNRREENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNRKLWGEPKSFKDISDLFVRYMSGKLESLPWSEAPISQEADAIKDDLVN
LNRRGLLTINSQPAVNGAKSSHPVYGWGPRNGYVFQKAYLEVLVSSEIIAELIIRIERNP
DLTYYAVNKSGDLKTNAPADSPTAVTWGVFPGKEIVQPTIVETISFLAWKDEFYRLGNDW
SSCYAPASPSRYLIQSLMENSYLINIVHNDFHESRGIYPLFEGLAINDLEHHLTAQPKLE
SNGIVSAKEQTNGIAAAA
>A0A7L2UR66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balaeniceps rex|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCHQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEADSYEADLRHLKEKVVAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A5N9CTA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MKIKDILTKTRPISFEFFPPRQAEGIPAVLETLDELKQYRPDFVSVTYGAGGSTRAFTEE
ITLEIKRNTDVEVMAHLTCVGQNKEELDEVLSRLQEEGVENIIALRGDPPKGTTEFVPVE
GGFKHATDLLHHVVSNYKFGVAAACYPEGHTESVDLDADLKFVKMKVDNGADFLVTQLFY
DNRFYFDFVERARAEGIEIPIIPGVLPVLNSAQVRRFTTLSGSKIPPDLDKLLDKYADSD
HSARDMGVEYATAQVRELWDYGVPGVHFYVLNRSYSVSRILDNLQIAGHQRQD
>A0A351ASA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rikenellaceae bacterium|TrEMBL
MKQYPSLEIVPPLKGMTKEELLNDIRPFIEFNPNYINVTCHRDEVVFEEQPDGSYRKKLV
RRRVSETAVCGAIQSEFKVDVVPHLICGGQTAEQIEFQLQDFKFMGITNILALRGDCLAG
EKRFTPFPGGYDHANELVEAIRRFEKENGCEGFFRIGVGGYPEKHFEAANMDEDIANLKR
KVDAGADYITTQMFFDNKVFYKFVDRCREVGITVPIIPGLKPISTSRQVSLLPKSFSIDI
PFELTSEIAAHEEDKEAVYVIGQEWATAQCKDLLAHGVPAIHFYTMGKSANVTRILKECF
>A0A1Q9AZW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium oryzae|TrEMBL
MAPQTLHPARRAALKLSFEFFPPKNEEMESQLLSTAETLKVYAPEFVSVTYGAGGSTKSR
SIDTVRKLIAERGLTNTAAHLTCVGASCAEVDAVIEEFLAAGVTRFVALRGDAPGGAGVA
YQPHPEGYANAAALVAALAKRGVRSISVSAYPEKHPESADVAADIDMLKRKVDNGATQAL
TQFFFDNDDFERYLNRVRAAGIDIPVIPGILPINNLTQVMKFAGLCGARVPQVLIDRLQP
LDDLPEERFREATLIAAEQIVDLAHRGLSDFHLYTMNRAPLISAVCDLVQFQRMDAASPA
A
>A0A2R4VZ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobium acidiphilum|TrEMBL
MRIKERYKSERTGFSLEFFPPKERDQEEKFKETIKKYIELNPLYVSITYGAGGTTQDKTF
EIVKFVNSFKAFAVMPHLTCIGATKDSVNFLIKKYDDLGVCNILALRGDPPKNVENFDIS
KGEFKHAIDLVKYVREYFNHFSIGVAFYPEGHAQASSFEEDFEHCIEKMRLADFAISQMF
FENSYFLRYRDLVAKRGVDITLVPGIIPIGNFEKIKEFSKFCKVEIPKKLEDIMSKASSQ
LDMKKAGIDYATQQCAELIKEGVKFFHFYTLNQFDLCSKVIENFW
>A0A3S9JDM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidipropionibacterium acidipropionici|TrEMBL
MLSTTSPAETIAELLTRAERPLTSFEFMPPRSEEDVYRLWRATDELVPLRPDFISVTYGA
NGSRRDRTLRCTQHMVASGLRTVGHLTAVSQSVAELEQTVSDYHDAGVDHILAIRGDMPG
GAAEPWVARPDGLANATELVRLVKRVNPGACVGVGAFPDCHPASGDLDLDARILAEKVEA
GASFAITQLFFIPEHYTDLVARVRALGCDIPIIPGIMPITSFSQIRRFGELSGTDVPADL
VARLSEVAEDRAAVREIGLEAAARLSCRLLDEGAPGLHYYTLNRSRATTELHAMVRDRRP
GLWDR
>A0A5N9GPL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MSTLVELVAKNRRRPFIVCDVSPPRSGNTEALSDLSSVTPDMFFVAANPGRTVRASSPSI
AQWIESNIKTPALFTMVTRDMNKTAMQTTLLGAHIMGLRNLVVVKGDNFNNSGCGTDKPV
EGFTPTAFIRSVRKMNNRIDFTGRSLTDPTQFCVGATLDISRKWCSEMSLADNKIRSGSD
FLIAQPNFDPDAAHKFLQEYQERRMSEMPIPIIWGIQIMSKGSISFANVPDHITKELDLG
NSGYEIALEMIHRYLEIGINYFYLVPPIFQGGRRDYESAQAVIEDL
>A0A519PIP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MKITDHINNSKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADHSFVPTKGGHCYATDLIQHIKNHNDGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNADFKYLKKKVDMGAEFIVTQMFFDNQK
>A0A328T4D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleiagrimonas sp. MCCC 1A03011|TrEMBL
MTPISLEFFPPKTEKQRAQFESALPKLRTLDPDYASVTFGAGGSTLSYTPQTVKALMDAG
LDGAPHLSCMGGTRAEIAALLDDYKAMGCRRLVALRGDMPSGMAGPGDFTYASELVAFIR
EYAGDHFHIEVACYPETHPQADDALADLRHFKHKVECGANGAITQYFFNPDAYFRFVDDA
RKAGIEVPIVPGIMPISNFTQLKRFSDTCGAEIPRWIVKRMQAYYDDVESVRALGADIVA
EMCRRLLDGGAPGLHLYTLNRAVATMAVVERLN
>U2E101|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides pyogenes F0041|TrEMBL
MKVIDLIHSNAKTAFSFEILPPLKGTGIEKLYEAIDTLREFDPKYINITTHRTEYVYKDL
SNGLYQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFSREETEYVLLDLQFLNITDL
LVLRGDKAKHESSFIPEKDGYYHAIELQEQINRFNQGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMESDLYWLKKKMEAGAEYAVTQLFYDNKKYFDFVKQAKSAGIHIPIIPGIKP
LRRKSQLSVIPKTFRVDLPEDLVKEVLKCKNESEVEQVGIEWSVKQCKELMSSGVPSIHF
YSIGAVNSIKEVAKLVY
>A0A0S8YTP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Leaf48|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYQSAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLANFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDAQSIQNFG
EQVITQMCERLLEGGAPGLHFYTLNQAEASLAVWNNLKLPR
>W5TIR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia nova SH22a|TrEMBL
MGQLRPRPDGTVPFSVEFNPPRDEAAEARLWRAAREFERMHPAFVSMTYGAGGSTRDRTA
RITGQLARETTLLTVAHLTAVGHSVSELRSIVGSYADAGIRNMLVLRGDPPGDPLGEWAK
HPEGVEYAEELVRMVCGLGDFHVGVASFPQGHHRSPDLDHDTRHLVSKLRAGAEYSITQM
FFDVDHYLRLRDRVAACDAEQGAKPIIPELMPITSLRTVQRAEELSGRALPAAVMRRLEH
AAGDDPEANRAAVRAAGIEIATEIGQRLIDEGAPCLHFITLNFAKATTEVLTNLGYTVTP
AAVSA
>A0A5Q0JWK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanihabitans sp. IOP_32|TrEMBL
MKVTEHIEKAKGKTLFSFEIIPPKKGNNIQELYDNIDPLMEFNPPFIDVTTSREEFVYIE
KEGLFDRKITRMRPGTLGICAAIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGINNV
MALRGDAMKGEQYFKPTKGGHTYATQLVEQMQNLNSGKYLHGILEANHKADFCIGVAGYP
EKHLEAPSMKTDLKRLKEKVDAGANYVVTQMFFDNKKYFEFVEAAQKEGINVPIIPGIKP
IAVNRHLQLLPQVFKIDLPEALITEVEKCKDNKQVRQVGVEWCIQQSKELLDAGVPVLHY
YSMGKSDNIHAIAKALF
>A0A1C5G614|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora echinofusca|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTEQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGDPGGDWVCHPEGVLHAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTEHFVR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFAKVADDPEAVRRLGVEQASEMCRRLLAEGVPGIHFITLNRSTATREVWQNLQ
VGARV
>A0A1I6TK46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora flava|TrEMBL
MSAALAAALRNASYEVLPFRSTEEKVLAHVPCDVPLTITTTEARGLEPTLDLAVRLSKNG
YTAAPHLAARLVRDRAELDEIAARLLESGVRRLFVIGGDAAEPAGEFPDAESLLLALAEA
GHDFAHLGIAGYPEGHGTIPDAVISEALRRKADHAHEIVTQLCFTPATTVDWAGRLHADG
ITTPVRVGIPGCVNRQKLIRVSAGLGLGQSARFLAKQSAMFWRFFLPSGYRPDKLVGALS
DQILDPTNAISGFHVFTFNDVEGTERWRQKQLAKL
>A0A2G2D386|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp|TrEMBL
MGLIELEEAKRALDVPLFAGLSGDADVSFEFFPPKSDKMEKTLWDSVVTLEPLNPRFVSV
TYGAGGTTRERTHATVARIARETDIPAAAHLTCVGASKAEIAEVAQSYWDAGVRHIVALR
GDPPAEGQAFEPHPQGYASAAELVKGLTDIAPFEISVAAYPETHPEANCPQSDLDNLKRK
LDAGATRAITQFFFTAEAFFRFRDAAAAAGIDAELVPGILPVSNVAQTRKFAGMCGAEIP
TWMNDLFEGLDDHPSARQLIAATVAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGK
RPAGAQQEKAA
>A0A8J5L632|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MKVAARARRLAAAGLVAAEAKMVAEANGRSAQRAGRRRRRRHLRPSRSPIGTTVAGSGRE
AKADGEVEVEVAALVCAADLVLPRHERAVRLRIESLADELPLDMRVPIVLDLVVHKQDVA
LGRSVDLTKFDGYDQLIEELDQLFEFNGELMAPNKNWMIVFTDNEDDMMLVGDDPWQEFC
AMVRKIFIYTKEEVHKMDSSTLNPKNEDCPDMKENDLEAQTKFEIGHVLGVLLASSPLLE
QAWTHCLRANACSANFIIDKSDDVVFIAFSRAQAAASPSGLGRGFFEPVSLYNSTHKLFT
PLGRGEEDSDGKPQPVLLQVCMETIMHLTCTNMPVEKIDHALNTIKANGIQNVLALKGDP
PHGQDKFVQVAGGFACTLDLVQHIRAKYGDYFGITVAGYPKAHPNMIQGDEGATLEAYNS
DLAYLKRKTLSVVLKFWKSFSHVKILELCEIFILWSAIREA
>A0A374C1M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium AM41-5BH|TrEMBL
MKIIDKLNEDRIHISFEVFPPKTDAGFEKVKDATDKIAQLNPSYISVTYGAGGGTSKNTA
KIASHIKHELGVESLAHLTCASSTKEEVRQVIENLKELEIENILALRGDIVPGMTFPSED
RFHYAYELVEEIKKHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITTAAQMKRSQELSGTVFPRRFLALLDRFGDYPD
AMKQAGIAYATDQIIDLLANGVKNIHVYSMNKPEVAAKIIENLSEVIKC
>A0A2W6TWQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MTALSFEFYPPKTDDQRAQLDRTAAKLKGHAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLQAAPHLSCVGGTREEIRELLKLYRAIGVKRIVALRGDLPSGMGFPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQASDALTDLRHFRTKIDAGADAAITQYFYNPDAYFHFVDA
ARKLGVDVPIIPGVMPISNFSQLRRFSEQCGAEIPRWISKRMQAYGDDAESVRSFGADVV
AGLCERLIAGGAPSLHFYTLNLAKPTNAVLERIGHN
>B0LJ02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rishiriensis|TrEMBL
MTTFSFEFFPPRTEDGVRTLWETIRRVEALHPDFVSVTYGAGGSSRDRTVAVTPRIAAET
TLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGAPKGPWTPHPHGFTHAWQ
LVELVRSLGGFTIGVAAFPEAHPRSPDWESDVRHFVAKCKAGADYAITQMFFRVEDYLRL
RDRVAAAGCDIPIVPEIMPATDYRQIRRFAELSDAAFPEGLARRLRAARHDPAAGHRIGV
EYAAAMAERLLAEGAPGLHYITLNRSSAALDIHRAIQNPRSLSVR
>A0A090EG41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium plurifarium|TrEMBL
MTALQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAQRLDHILHDEITETQVDMVK
TAH
>A0A3A6P7N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfarculus sp|TrEMBL
MSAKTPSRLERVLAAGHKAVTSECGPPRGSDPEVILRKARLIREHVDAVNVTDNQTSVTR
LCSLASCVHLKLAGLEPILQMVTRDRNRIALQSDILGAASFDIHNLLCLSGDHQSFGDCA
QGQNVHDLDSMQLIQTARHMRDEGRFLGGEEILRPPKMFVGAAANPFADPFEIRVPRLAK
KVAAGAEFIQTQCIFNLEKFELWLSQARERGLLEKVYILAGLTPLKSAGMAKYMKNRVPG
MDVPEEVVKRISGVPKEGQAQEGISICVEAIERLKEAPGVAGFHIMAIEWEEKVPEIVER
AGLFPRPALD
>A0A1N7ESF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella cuniculi DSM 21768|TrEMBL
MTQSLLNRLNDIETLLNSVKSELQNQTKPNNTNNKVPFSFEFFPTKTDEAQDKLLTTFDT
LNALNPQYFSVTYGAGGSTRERTLGIVEALSKQSDTPIAPHMSCIGDTKAEIGELLDFYK
SLGVTRVVALRGDLPSGQVGYGELPYALDLVKFIRQHSGEHFTIKVAAYPEMHPQARNFD
ADIDNLVAKYHAGANEAITQFFYNADSYLFLRDKLAKKGVHQDQFPIIAGIMPITNASNI
IRFADGCGADIPRYIRKQLADFGDDRKAIRQFGFEVVHTLCQRLIREGVPALHFYSMNST
EPNKELVKALGLTS
>A0A1B9DB06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium malmoense|TrEMBL
MSAGPECPKRMEFGPCGGVRPDGQCEMRPGACAFDDVVAWSGHQPAPRRVRAPLVLTDFS
CTPFDRDDLAATAAVLAPGCDAVLVGEHQNKPDFPPTLLGSLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSINVETVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASTGVVAAVP
ETPTAPPVRARPARLVEKQRAGASLAVLNHVPFPGMVADFMTTARAAGLTIPVIAAVAAF
TDSVSAAVLQGLPGLELDQAVTERVLSAPDPVDAGIAAAVAEARALLSIDGVEGVNVSGL
ASASGPRIGAEIKAEIGRQIREGRR
>A0A1V4QNP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca sp. 4484_104|TrEMBL
MKTESKLEKILESGQLAVTSEAGPPRGAEPEVIRKKGEMLKAYVDCCNVTDNQTAMVRVC
SLASCIILKQMGLSPILQMTARDRNRLAIQADILGAYAFGINTMLCLTGDHQSFGDHPTA
ANVFDLDSIQMIQGVNKIRQEGTFMGGAKMTLAPKMFIGAAANPFADPFELRVMRLAKKI
AAGVDFIQTQCIFNMDKFGKWMQMICDEGLDQKVHILAGITPMKGLGMARYMKNKVPGMD
VPDEVINRLKGVPKEKQADEGITMAVEQIQQLKEMKGVHGFHIMAIEWEEKVPEIVERAG
LLPRPKVD
>A0A524JTT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteriales bacterium|TrEMBL
MLFSDYSNYKDKKPIISFEIFPPKTEKGYDNLKNELSELAALNPDLITVTYGAMGTTREK
TLDIASLIKNHFGIESACHLTCVGATKKELDIILQRINDAGVRNIVALRGDPPEGTQTFV
KPEDGYSYGNELVEHIRNFEAKTGNKCHFGIAVAGYPEKHVEACELATDLVNLKRKVDAG
ADVVITQLFFNNDFYFDYVKRVRDIGVTVPIIPGIMPILSAKQIGRITSMCGTTIPLELK
EKLDSAIDDDNKARDIGIELCIQQSKELLAQGVPGIHFYVLNKSSHMITIMDALSDDLQN
LRA
>A0A345RDG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. JL08|TrEMBL
MTHRTPPAVSFEFFPPKDLAGSFRLWDTVQSLAPLEPDFVSVTYGAGGTTRDLTRDAVAT
LHTASGLNVAAHLTCVDATRAETLKIAADFAAAGVSDIVALRGDPPKGTEKFTPHPDGFD
NVCDLISALADTGTFNIRVGAYPEKHPEAADMAANINWLKRKIDAGANSAITQFFFEADT
FLRFRDACADAGITAPITPGILPIENWAGARAFARRCGTTIPAWLDSAFEKATRDNRADL
LATAVCTELCDKLLENGVDTLHFYTLNRPELTRDVCHALGITPRVQLRHVA
>A0A3N4P1M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureibaculum marinum|TrEMBL
MKITEHIKQAKGKTLFSFEIIPPQKGRNIQELYNNIDPLMEFKPPFIDVTTSREEYVYID
KEGLLDRKITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIENV
MALRGDAMKHEQYFKATKGGHSYASELVEQIQNLNSGKYLHDVINVEDKADFCIGVAGYP
EKHLEAPSLQTDLKRLKQKVDAGADYVVTQMFFENKKYFDFVEAARKIGITVPILPGIKP
IAVKRHLQLLPQVFKIDLPEELIKEVEKCKDNKEVRQVGIEYCIEQSKELLAAGVPVLHY
YSMGKSDNIKAVAEGIF
>A0A2V1P2Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salibaculum griseiflavum|TrEMBL
MTRPALSFEFFPPKSLPQSFRLWDCVTALAPLGPDFVSVTYGAGGTTRKLTHEAVEAIGA
QTGLDVAAHLTCVEASKEETLAIADQYRAAGVNRIVALRGDPPRGAGRFVAQPDGFSGSV
ELVGALVDRGFDVTVGAYPERHPDAVDHAADIEHLKRKIDAGADTAITQFFFEAETFFRF
RDACEKAGIDATLIPGILPVENWTGTRRFAQACGTTIPPIVADAFENAERDGGADLLATA
LATELCDDLLQGGVEHLHFYTLNKPELTRDVCNALGIQPRVKLQNVA
>A0A1F9BGY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_60_28|TrEMBL
MQLQGKLTSGEFAILAEMEPPKGADVVAMIANAWAVKGKVDAFVIPEMSNAVMKMSSLGG
ALLLQSRGLETVLQACCRDRNRLALQGDLLAAQALGVPNVMAVAGEEITHGDHHKARAVY
DIDLLELLGAIQTLQTGRDMAGVDLQGAPSFFVGSTLKVTPRGEAWDKELAELDEKMAAG
AGFFVTQPIFDPGALAKLQDSLKERRAAVIPTVLLLKSVGMARYINRFMDMKVSEDFINR
IQKAPDRVRECVAIAGELVAAFKAQGCPGVNISTIGWEDRLPAILAAAGV
>A0A357N6L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MTAISFEFYPPKTDEQRGQLDRAAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAPDALTDLKHFKAKVDAGADAAITQYFYNADAYFHFVDE
VQRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMLAYGDDSESVRAFGAEVV
AKLCERLVAGGAPGLHFYTLNLAKPTVSVLKLLNG
>A0A453M861|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aegilops tauschii subsp. strangulata|TrEMBL
VCVETMMHLTCTNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDKFVQVAGGFSCALD
LVEHIKAKYGDYFGITVAGYPAEAHPEVILGEEGATEEAYSKDLAYLKRKVDAGADVIVT
QLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTKIPAEITAALDPI
KDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNLGLIEESKLSRTL
PWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWGDSRNPSYGALNDHQFTR
PRGRGKKLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPETTIIDDQLVKIN
SKGFLTINSQPAVNAEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFPSL
TYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGWA
CLFPEGDSSRELLEQIQKSYYLVSLVDNDYISGDLFAAFKEI
>A0A1E5E6D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio rumoiensis 1S-45|TrEMBL
MSYSHAGHIDALNHNVADLAGKINVSFEFFPPSSEKMEETLWSSIHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASRDELKDIAKDYWNNGIRDIVALRGD
LPPGGGKPDMYASDLVELLKGVADFDISVAAYPEVHPEAKNAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVNAGIDVEIIPGILPVSNYKQAKRFADMTNVRIPSWMAKQYE
GLDEDPVTRQMVGASQAIDMVRTLSREGVKDFHFYTLNRSEMTYALCHTLGVRPR
>A0A7C8R9F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orbilia oligospora|TrEMBL
MHIKDKIAACEKAGKPCFSFEYYVPKTAQGVQNLYDRMERMGSFGPQFIDITWNAGGRLS
NLTTEMVNVAQTVYGLETCMHLTCTGMEKEKVDNALQEAYNGGCTNILALRGDPPRENEK
WSAVPGGFRYAKDLVKHIREKYGDYFDIGVAGYPEGCDDEVDPDILLDHLKEKIDAGGTF
IITQMFYDVDIFLDWVNKVRAKGITVPIIPGIMPIHTYAAFIRRATWTKIHVPEKWLEVL
EPVKNDDVAVRDIGRDLVVELCKKILAAGINQLHFYTMNLATATRMVLEGLELMPSLEAR
ELPALPFKSSLGLGRREENVRPIFWKNRHKSYVARTQEWDEFPNGRWGDSRSPAFGELDT
YGIALKGTTEQNIKLWGRPETVAEIADLFVRYIDGKLETIPWSDSPIDASAEPIKAQLSE
LNKRGFLTTNSQCALNAVKSSHPIHGWGPKNGYVYQKMYVELLVSPDVLSELITRIERSS
DLTYYAVNKAGVLHHNAPAGGSPNAVTWGVFPGKEIVQPTIVELISFLAWKDELYRLGED
WAACYPQSSASRHIISSVMENWFLVNIVNNNFLDNDSIFELFKDLKIDNLNEKIPVDEYL
QNLKITDGINGTAHEATNGAPAA
>A0A836GGF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acromyrmex charruanus|TrEMBL
MCERNDTDGNDNSSTPDFHIENPRKTVVDLRQLLKDKISKNEIFFSFEIVSTRKSGAFYR
RLLIDMEEYSPLFYALTWHNEAASDNDDYLPLDLVENFPANTLLHLAAKSLKRDEVIYIL
KKAIAFGIINIFALRGDSLSENGDFEHAADLVVFIRQRFGNTFCVCVAGYPQMHPESPSK
KLDLHYLKAKVEAGADFIITQICFDSRVLINFVRDCREIGIQIPILPGILTPTNHACLEK
MIDICRLDVPIKIKEDLARMKDDDQAVRKYSVDLIVQIITDVIRNGATYGFHLFTLNRLS
LVTEICKRIESFKAENL
>A0A7W7YR99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella fusca|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTTELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNGKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPFRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGV
GPMASAKTAKWIRSNVPGIHIPDAVIKRLEGAEDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEIVHDSGVLKGRRPWTREPNPVDQMVAERIEAARSGQEQDQQQMAEKAA
SQPH
>A0A6I5GTD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID89|TrEMBL
MNPLSTARTAVGALLLEDFSLEMTGKDVAKLEEARETIPQGTRINITFLGNEDLRMRLEA
SRAVKRLGFVPVPHLSARRLGSRAEFAEFLAALRAEGACDNVFAVGGDPARPKGPYEDSL
ALIESGLLQEHGVRHVGISGYPEGHPDIAADVLRTALRDKSAALRARRLDGGVITQFCFD
VDPVLAWLAQLREQGITLPVRIGVPGPAGVRRLMSYAARFGVGTSASIAKKYGLSITNLM
GTAGPDRFLHALTEGYDPARHGDIKIHFYTFGGLRATSEWIARFRKEHHV
>A0A0V0Q710|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. MKU1|TrEMBL
MTTPAISFEFFPPRNLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETLQIVQDYAAAGVHEIVALRGDAPQGQERFTPHPDGFANSV
ELIEAIAARGDMTVRCGAYPEPHPESPDTAADVAWLKRKVDAGATSAMTQFFFDAETYFR
FRDSCLAAGIEAPIIPGILPIQSWAGTRRFAERCGTSVPQWAEDAFAAAGKEGEAQLALD
VCVKLCERLVEGGVDKLHFYTLNKPELVLKVCAALGIAPKGEFSRVA
>A0A4Z0ALZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas kairouanensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTQYKSAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEEDLKNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCESLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A317LQH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis sp. L17-MgMaSL7|TrEMBL
MLAAPTRSVAPRTPASRPRHIRDLLDSGEPMFSFEFFPPRNARAQERLWRAIREIEALGP
SFVSVTYGAGGGTRDLTVETTERIATDTTLMPVAHMTLVDHSVAELRHLIGRLADAGVSN
MLAVRGDPPGDPDGAWVQHPDGLTYAEELVRLLKESGDFCVGVAAFPYKHPRSVDVEVDT
DHFVRKCEAGADYAITQMFFDAEDYLRLRDRVAARGCEVPIIPEVFPVVKLASIPRSEKL
SGAPFPPALAERFQRFGDDEEAVRAFGIEHAQRMCERLLSEGAPGIHFITFNQSTATREI
YREVAGHRVRGAAAERP
>A0A521PA65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MAPRSLAEARALLLSPLGPVARAGQDLSRPRVSFEFFPPKSDEAEASLWRAVTRLAPLAP
EFVSVTYGAGGSTRERTHRTVERILAETALTPAAHLTCVEASRDEVDAVIEGYRDAGVRH
IVALRGDPPGASGIGGAYVPRTDGYANATELTAAIASKGGFEITVGCYPEGHPESPSAAH
DLDVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTVPIIPGIMPVSNFNGLKRMS
AACGAAVPDWLAAHFDGLDDDPETRKLIAASVAAETCARLQEEGFADFHFYTLNRADLVY
AICRVLGVRETKVAAV
>A0A554VSW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. KBS0703|TrEMBL
MFPVRIEIIPSEGIVEQVEALVPLTTTLTVTCLPHHGIERTMRTAVQLSVLGYQVIPHLA
ARSLHSRADLTGILRDCDVAGIGEVFVIGGDRKQPAGPYESALPVLEDIAQYSGGMMRAG
VAGYPEGHPSVGPVDMLDALLAKQHLASHVVTQMCFSAPKILDYTALLRREGVRLPVWAG
VAGSVPRTKLVSLATQIGVGSSLRFLSRKGPLARKLLSGDRYSPEGLVSGLESQPGSVAG
IHLYSFNSLDSVPGAPGQAATSSALQQALIRGAARDN
>A0A6I4IZ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas horti|TrEMBL
MTLSLSQMEEARRALDAPLFAGLPGDIGVSFEFFPPKTEKMEAQLWESVQTLAPLGPRFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEASRAEIDAVAEEYWAAGVRHIVA
LRGDPPVAGEPFRAHPGGYANAAELVAGLRSLHPFEISVAAYPECHPDSGTQVADLDNLK
RKLDSGATRAITQFFFSPDCFFRFRDAAAAAGIESEIVPGILPVSNVAQTRKFAGLCGAE
IPGWMDRLFEGLDDRPAARQLVAATLAAELCRKLYAGGVRHFHFYTLNRAELAYAICHLL
GLRPVATAQEKAA
>A0A258KR28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. 35-67-4|TrEMBL
MTLPPTLSGARRVIGPVARAGERGQSQGGGRPRVSFEFFPPKTLAMEESLWQAITRLAPL
DPAFVSVTYGAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASREEVDEVIREYWETGV
RHIVSLRGDPPPTEGGIGGVYAPRADGYANATELTRAVRAIAPFEVLVGVYPEKHPESPS
IEHDIDVLKAKVDAGASLAISQFFFDIDAFLRFNDKVRAAGITIPIVPGIMPVTNFNGLK
KMSQACQTAVPTWLANLFEGLDHDAETRRLIACSVASEM
>A0A1F4P404|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFOXYC12_FULL_60_6|TrEMBL
MNSTVRFPVSIEFFPPKTPEGVEKLRVVRQQLYALMPEFCSVTFGAGGSTQEGTFSTVRD
ILSEGVSAASHFSCIGATRAGVREQLATLKAMGVKRLVALRGDLPSGYGTGGEFHYASDL
VAFIRAEMSDDFYIEVAAYPEIHPQAKSAESDLKAFAAKAQAGANSAITQYFYNSDAYFR
FVEDADALGVQIPVVPGIMPIASSSQLMRFSDACGAEIPRWIRLRLLGFGDDTASIKAFG
LDVVTDLCEQLRAGGAPGLHFYSMNQSAATLEICQRLGLAA
>C0Q459|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella paratyphi C (strain RKS4594)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A258YRA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriia bacterium 24-36-13|TrEMBL
MKVTEHIQQAKNTLISFEVLPPLKGKTIQHVFDHLNPLMEFKPSWINVTYHRSETAFKKK
VDGTFEKVEVRKRPGTVGICAAIMNHYRIDTVPHFICGGFNKRESEDALIDLNFLGIDNV
LVLRGDAAKNEASFEPEADGHKYAIDLQKQVVNLNSGIYLDEDIQNGGKTNFCIGTAGYP
EKHFEAPNLEIDLQRLKEKVDAGADYIMTQMFFDNQKFFDYVKACRDMGITVPIIPGLKP
ITNKKQLSVLPRIFHVDIPTDLSNAISKCKTDADCEQVGTEWLIQQSKELKAFGVPVLHY
YTLGKPKVIWNVVNAVC
>Q7V4E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus (strain MIT 9313)|TrEMBL
MSSALQRSIEAGAVTITAEVMPPRGADPVHSLTMAQGLKGFVHAINVTDGSRAVMRMSSL
ALCRLLLDEGLEPILQLACRDRNRIALQSDLLGAHALGIRNLLCLTGDPVRVGDQPEARP
VHDYESVKLLHQVSAFNRAEDPVSGLLPDGATAFFAGAAADPNCQSLSGLRRRLERKKEA
GARFLQTQMVMKPAVLEHFCNEVANPLGLPVLAGVFLLKSARNASFINRVVPGACIPESL
VVRLEQASDPMAEGIAIAAEQVRSYLSLTQGVHLMAVKAEERIPEILDQAGISLVPV
>A0A2L0H6A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium fredii|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMEIQLFQTISDLSVFAPAFQTVTYGAGGSTKAR
SLTTVKRMIGEMGLNNTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGSA
YEPFPGGYESSASLVKALRARGDFEISVSAYPEKHPESADVAADIDMLKRKVDSGATRAI
TQFFFDNDDFERYLERVRRAGVQIPVVPGILPINNLTQVIRFAGLCGSKVPEAIISRLAH
LDDQPEERFKEASHIAAEQIVDLARRGLRDFHLYTMNRSPLIAAVCELVGYQRRPLRPAA
APSYPAVATA
>R7MJJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:624|TrEMBL
MKVSQRFKEKTVFSLEIFPPKPNSPENVIYDTLDELKDIKPDFISVTYGASGGSNCSKTI
EITSAIKNKYQIESAVHLPCIYLTKQNVLDILNTLKENGIQNILALRGDVNPDLAPVNEF
KHANELIEFIKLNGDFDIMAACYPEGHNESSGLVEDIVNLKRKVDSGVDHLITQLFLDNN
YFYSFYERTQIAGINVPIEAGIMPVTNKIQIERMVKLCGINLPKKFMKMIEKYENNPIAL
RDAGIAYAIDQIVDLISQGIDGIHLYTMNKPYVANKAYDAIKNLISYSNAIK
>A0A1S2NGU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia timonae|TrEMBL
METPDFSIEFFPPKTPEGAEKLRIAREKLADLNPKYFSVTFGAGGSTQQGTLATVREIQA
AGHEAAPHLSCIGATRESIRDVLKQYQDSGIRRVVALRGDLPSGYGGAGELRYASELVEF
IRQETGDWFHIEVAAYPEMHPQARSPQDDLQAFARKVQAGANAAITQYFYNADAYFQFVD
NVRKLGVDVPVVAGIMPITNYMQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLAGGAPGLHFYSMNQAAPTTAIWQRLRA
>A0A1W2C575|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter nyackensis|TrEMBL
MKIIDHIHNAKGKTLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HPNGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDSSFVPTANGHAYASELLSHVVDMNRGKYLHDDMESAEKTDFCIGVAGY
PEKHFESPNLDTDFKYLKHKVDTGADFIVTQMFFDNNKYREFVEKCRANGINVPIIPGLK
PITSSKQLISLPKIFHLDIPLALTEAVHACKSEKEVKEVGIEWMINQCNELKAMGAPVLH
FYTMGNPEPTKRIAQAVF
>A0A7S8C255|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kaustia mangrovi|TrEMBL
MTVNALASVDVQQVAHDRGGEPVQAFLAEYSLEITPRQSDRVAEIAARLAPGTKVYVALI
DPAEAPQQVVAAKALAAHGLAPVPHMPARQIRNAADLGERLARLTGEAGVTQALTLGGGL
PEPFGEFSSAIELLRTGLFEEYGITRIGFAGHPEGNPDITKVHGEGALMAALREKQAYAR
EAGLEAYLATQFLFEPGPVVNWARTLRSQGITLPVHVGIPGPATVKTLVKFAAMCGVGAS
ARVIRKQAMNVTKLLTVSTPDDLVSALARASREQPELDIRQAHFYPFGGFDKLFSWLDTV
KR
>A0A329TNZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MIDVRAHLARKPLLFDGGMGTYYKAKPGTECEQGNLLDPAGVRKVHREYLAAGAEAIKTN
TFGLPRMAAARQPDWQALARAGWKLAAEAAVETGAAVFADLGPAPDTEAAPAGSIYTAVA
RCFVEQGAKNFLFETLSSDAGVLEAVQAVKAQVPDAFVLVSFAVLPDGYTREGMYSKDLV
RRMTESGIVDAVGFNCVSAPGAMRTLVQQLGSTALPLSVMPNAGYPVVTRTQVKYQGKPE
YFAKELARIAAEGVRILGGCCGTTPAHIAALRATLDSLPAVEKAAPAVQVSTPGAPTVEK
DDAFLRKLNAGKKVIAIELDSPKDADLTNYLAGAKRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGLCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPMTVFGALNLNARNFEVELRRAGEKLENGMSGFL
TQPVLSEQAVENLRRTRETLGERAKILAGIMPVVSQRNAIFMENEVNGIHVAEEIMEAFA
GLDREQGEALGLEISLKMAREALPYADGFYLMTPFNRVALMERLIARLKTELLQEQ
>A0A844DTF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MMNIRELLQTRPLLFDGAMGTYYKAAPGVECEQANLTDPAGVLAVHREYLAAGADAVKTN
TFSLPRLAAAHTPGWEQLAQAGWQLAVQAAEETGAAVFADLGPAPDTEAVPAGQVYTAVA
KQFAALGARNFLFETLSSDAGLLDAVGAIKAEVPDAFVLVSFAVLPDGYTREGMYCKDLA
RRMQESGIVDAVGLNCVSAPGAMRTLAKQLGGTLPLLVMPNAGYPVVTRTQVKYQGRPEY
FARELGRLAAEGTVQILGGCCGTTPAHIAALRAELDSLPVVEKTAPAEEFSTVKEQTVEN
EDSFLRKLNAGEKVIAIELDSPRNADLTGYLEGAKKLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGLCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPGPMTVFGALNLNARNFDVELRRAKEKLENGMSGFL
TQPVLSAQAVENLKKSRETLGADAKILAGIMPVVSQRNAIFMENEINGIHVEDWIIEKFA
GLDRAQGEELGLAISLEMAKAALPYADGLYLMTPFNRVALMERLIGRLKQEVLGAY
>A0A841CUC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix tamanrassetensis|TrEMBL
MKTVLERLNGSNPVFSVEFFPPRDAADELVLWRAIRELEALDPAFVSITYGAGGSSRDRT
IRTTGRVAQETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILAVRGDPPGDPNGEWV
RHPSGLTYAEELVRLCRELGDFCVGVAAFPYGHPRSADLDTDTKYLVGKLRAGADFAIAQ
LFFQPEDFLRLRDRVDALGCDTVLLPGLMPLTTPRTLAKTVELSGAPVPDVVARRLDPYA
DDPAAFRTAGIDLVTEMGERLLAEGVPGLHFYTLNRSKATREVVARLGLVPARA
>A0A5N5NX92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coniochaeta sp. 2T2.1|TrEMBL
MHIREMLADAERTGEPSFSFEYFPPKTAQGVQNLYERIERMYNFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYFGLETCMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPPREKEK
WVATEGGFQYARDLVRHIRDTYGDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGATF
IVTQMFYDVDNFLRWVDKVRARGVSVPIIPGIMPIATYASFIRRANHMQCKIPDGWMTRL
DPVKNDDVAVRELGKVLVAELCRKILAAGIRHLHFYTMNLAQATRMLLEELDWMPSVNRP
LKQALPWKQSLGLGRREEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEENRRKWGEPRSVADIASMFVRYLEKKIEALPWSESPLTSEADSIKDDLIA
LNKRGFLTINSQPAVNGVKSSHSIHGWGPPNGYVYQKAYIELLVHPDVFPDMVRRIEANP
DLTYYAVKREGDFTTNAPNDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGTDW
ARCYEPETPSRLLLEDMMEHWYLVNIVNNDFHQPRTIFEVLDGLTVPGLDTVPEPEPATN
GVHHTETATAAAA
>A0A3C0R118|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spartobacteria bacterium|TrEMBL
MNLIEELESRVVCGDGAIGTLLLDRGVPVDRCLEELCVSEPDRIRAIHEEYIAAGARVIE
TNTFGANVIRLARFGFENRVREINKAAVALARQAARGEDVCIAGSVGPLGITESEAEERG
IDRAECFREQIAALLEEDVDLIFLETFMSFEEMEIALRAKPQGDCRVVSLFACEPEGRLQ
SGMPLMDAFARCRELGAAVVGANCLNGPRAMVQLFEKLPAGGLLAAYANAGYPRYTEGRY
VYPTAPDYFANAAREMAAQGARLIGGCCGTTPAHIAAVAKAIVDLRPVRSKSVRVISEPI
TAPLRIEHKPEESLLDKIDNGKRVIICELDPPKTLVFEKYFTGARSLVDAGCDAITLADN
SLAILRVSNLAVGAILKERFGITPLLHLSCRDRNLLGLQSELLGMAALGMRHVLPLTGDP
ARVGDHPGAASVYDVNSIELISIIKQLNAGFTYAGKPLKASPNFVIGCTFNPNAKNLDAQ
VQRLERKVAAGAQFVMTQPVFDVDRVEEMHRRTQHLRVAIFTGVWPLRSARQAEFLHHEV
PGIIVPDSVRGELATLDEDGARGCGMRLAEKIITAVLEHFPGVYLITPFLHYETTTELAK
FARSL
>A0A521CAC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium nitrogenifigens|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFTPKAGGNHYAIDLVKQINDLNCGKYLHEVMDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVNAGADYVVTQMFFDNAKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAVQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A4Q0MIX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hansschlegelia zhihuaiae|TrEMBL
MPNARLSRAARRPIRVSFEFFPPKTPEMEAALWRSVERLAPLGPTFMSVTYGAGGSTRER
THATVERMVRELDVPPAAHLTCVSASKAEVDAVVESYREAGVRHIVALRGDPAGGVGTAF
EPHPDGYKSTADLISGIRARAPEIELSVSAYPEKHPESPSVEADFDVLRAKVDAGANRAI
TQFFFDNGHYLRYVDEARKRGIHVPIVPGIVPVSNFKQTANFAARAGATVPDWFAARFEG
LEDDPSTRQLVAAAVAAEQVLDLVDHGVKDFHFYTMNKADLVYAICHLLGLRPAEGMGKR
AAA
>A0A4V2W3V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Biostraticola tofi|TrEMBL
MSFFHVHQREALNQNLAELQARINVSFEFFPPRTSEMEQTLWQSIDRLSELKPTFVSVTY
GANSGERERTHSIIKDIKERTGLDSAPHLTCVDATPQELEAIARDYWQSGIRHIVALRGD
LPPGSGKPSMFASDLVALLKKVGDFDISVAAYPEVHPEAKSAQSDLINLKKKVDAGANRA
ITQFFFDVESYLRFRDRCVATGIDTEIVPGILPVSNFKQLQRFATMTNVKVPNWMTQMFD
GLDNDAETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPEAALPG
QSLVRASA
>A0A014BFG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_8|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>J4Q3B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. AS14|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANELQIPTIAHLPAVYLTKEMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A0N0KF05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas sp. AAP120|TrEMBL
MTDLLPQLPAISFEFFPPKSEEMERNLWQAISRLAPLAPRFVSVTYGAGGSTRERTHSTI
ARILNETSLTPAAHLTCVDAPCADVDDVVERYYEIGVRHIVALRGDPSSGLGGAYCPHPQ
GYRSSADLVASIKRRHPDIDVTVSAYPEKHPESSGFDADLDMLQAKVDAGATRAITQFFF
DNDLYFRYLDRVRARGINIPIVPGILPVQNFKQASSFATRAGASVPDWLAKQFEGLDDDP
DTRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGLRPQAAAQKAA
>A0A1F9PSI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium GWD2_61_12|TrEMBL
MSRLEQAFAAGTFVVTAEIAPPKGIAVAAALAKAKALPEGVTAVNVTDNQGANMRLSPLA
LSALLVREGIEPVLQLTCRDRNRLALQSDLLGAAALGVENLLLLSGDHARFGDHPEARSV
FDLDSVQLLQAVSGLMAGRDMAGKALNGVPSFFVGAAVAPAAEPFDLMLSKVNKKAAAGT
RFFQSQAVFVPAELERFMLAVRPLQVPVMLGVLLLRSANMARFLNANIPGVQVPAVLVDR
LDAAVDPLAEGVAIAREMVQAARDLCQGVHLMTLGHEDKISAILAR
>A0A257PFH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomonas sp. 20-64-5|TrEMBL
MRMASAQSVSLSFEFFPPKTPEGADKLRAVRQRLYARQPEFCSVTFGAGGSTQEGTLQTV
RDILAEGVDAAPHLSCIGASRESVRGHLRAFQASGVKRLVALRGDLPSGYGIGGEFHHAR
DLVAFIRAEMGGAFHIEVAAYPEMHPQAKSPLDDLRHFADKVRAGANSAITQYFYSA
>A0A3S0DJR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium|TrEMBL
MKVIDHIRQAKDTLVSFEILPPLKGKTINSIYDHLDPLMEFKPSFINVTYHRSEHVFKKK
LDGTFEKVEVRKRPGTVGICASIMNHYHVDAVPHLICGGFGKRETEDALIDLHFIGIDNV
LVLRGDAAKNETYFEPHAEGHRYASELIKQVVDLNSGIYLEEDIRDGFRTNFCIGVAGYP
EKHFECPNLEIDLKYLKNKIDLGAEYITTQMFFDNKKYIEFVEKCREAGIDVPIIPGLKP
ITNKKQLSIIPRTFHVDIPTDLSNEIMKCKTDDECKKVGTEWLIQQSKELKAFGVPVLHY
YTLGSAKVIYNVVKEIF
>A0A416SGR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. AF19-13LB|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A1F8N7U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_57_8|TrEMBL
MVSRFKEALDSGKFVITSEVAPPKGTNLEKMFHHIDILKDKVDAINVTDHQSSVMRFPSL
GGCLAVKERGGEAIMQMTCRDRNRMALEADLLFAYSRGIQNVLCLTGDAVPVGDHKEAKG
VFDLDSLQLLKAIGQMMSGLDLGGNKLEGTVAFCAGAIVTPEARPIEPQLIKFEKKVEAG
AEFFQTQAIYDLENFTRFMEYARKFKIKILAGIVLLSSARMAKYMTENVPGIFVPQILID
ELSKVSKDAMLAKGI
>A0A0M3ATB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium chungbukense|TrEMBL
MTLSFPSVEEASQAWQAPLYADLAGDVNVSFEFFPPKTEKMEEQLWSAIQTLTPLAPKFV
SVTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKAEIDEVVDAYWEAGVRHIVA
LRGDPPEAGSKFEPHPDGYKGAAELVEGLVKRHPFEISVAAYPETHPDALSAQSDIDNLK
RKLDAGASRAITQFFFEPDTFFRFRDTVAAAGIDAEIIPGIMPVSNFAAVQRMSAMCNTD
VPGWMGKLFEGLDDHAAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPATLEKTA
>A0A0Q8UQ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root224|TrEMBL
MSARSETARGTLKDTLARAGYEVIPLRRAEEDVLASVPRDVHLSVTASPGKGQDATLELA
ARLVGHGYSVAPHFSAHQVRSRSHLEELLAHCREANITEAFVIGGDRTDTPSEFADALAL
LRAMHDLGHGFTDIGIGGHPEGHPAVSDEVLMKAMQDKALLATHITTQIVFDPAVILAWA
RDLHARDVTLPIHVGVPGAVHRQKLLRVSSGLGIGESARFLTKQQGMLWRFFVPGGYRPD
KIMRGLAPHLGQPDNHLAGFHVFTFNDLASTEEWRTRSLKRLA
>A0A7S9DY02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinimonas marina|TrEMBL
MVSYAQGIDALNQSLSELRDINVSFEFFPPKSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHEVVKRIHQQTGIAAAPHLTCVDASRDELKQIAQDYWDSGIRRIVALRGDLP
PGMEKTEMYASQLVTLLKEVADFEVSVAAYPEKHPEAANPQADLLNLKRKAEAGASEAIT
QFFFDTSTFLRFRDRAAATGIELDIVPGILPVTNYQTLLKFAEFANVHVPGWMHKMFDGL
AEDDQTTRNLLGANIAMEQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVR
>A0A3D2Q5C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotomaculum sp|TrEMBL
MSKLAKLLQQGEFVVTAEINPPKHACPENIKRQAEFIARYVDALNITDCSTAVVRLSSIA
AGFHILSCGVEPIIQMTCRDRNRIAMQSDLLGAYSLGMRNMLCLSGDHQKFGNHPTAKNV
YDLDSIQFIYYLNRLQTEKVFFSGESIKEKVPHFFIGAVINPFAAPREFQVIRLEKKIRA
GAKFIQTQCIFDLEGFADFMEQVEWRGLHQKTHILAGVAPLKNYRVAQYMQNNVPGIVVP
DKVTNRMQRAVHPAREGIAICVEQIKRIREMKGIKGIHIMAMGWVEVIPEIVSRAGLYPR
PKIN
>A0A7C6H8G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MQIASLFQKNRPVFSLEIFPPKRIGPIDTIYKTLDNLKDLQPDFISVTYGAGGNAGDTTT
ADIAGNILNRYGILPLAHLTCVNYSRQEIGQILNILKEKEIKNVLALRGDINPDITPKKE
FSYASDLIKYIKDKGDFYISGACYPEGHVEAKSLDEDIKYLKMKVEAGASHLISQLFFDN
DYFYSFLEKVRKAGITVPIQAGIMPVINKAQIERMVTLCGASLPAKFTKMMQRFEHSPEA
LRQAGIAYAVDQIVDLVSQGVDGIHLYTMNNPFVARRITESIQGIINA
>A0A1J5EY49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium CG2_30_60_27|TrEMBL
MNNAHCFQTSLRDPEDFTLTFELVPSRGGRSHEHGRALDFAREAVQDGRLRAVSITENAG
GHAALSPEVLGVEILHLGLDVIVHFSCKDKNRNQMESLLFAWDRLGLRNLLVLAGDYPKP
GYQGLPKPVFDLDTVQALDLVGRMNQAIFGADQLSALADPAEATAFFRGVVVSPFKYLEA
ELRMQYAKLHRKAAAGAGFVITQLGFDARKFQEVLLYLRANHLELPVLGNVFIPNLTVTE
LMYRGEIPGCVIPAALYRQIRQEAASTDKGKGARLERAAKLLAVLKGLGFAGAHIGGPAL
VFADVKRVMDRAEELAADWSACLPELHFWPDDSFYYFKRDKASGLNQLEPSPTAGRIAGR
LSGYDLTRRIHDLAFAPVGPLHVPVKKLCLALAATRLAPGMAGLEHLIKFLAFRCQNCGD
CTLSELAYLCPQSGCAKYLLNGPCGGSRDGWCEVYPGVKRCLYVRVYERLVAHGCFQETL
TDLVPPRDWALNNTSAWVSFFSGRDHVHLGEK
>A0A1U9NIH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerohalosphaera lusitana|TrEMBL
MLKEELQNILQQRVMIGDGAMGTMLYQRGVFVNTCFDELNLTKRELIKSVHAEYIEAGCD
FVETNTFGANAYKLGKFGLVDSVEAINKAGVEIAKEIAQEHEVLVAGSIGPLGREIVDFG
PDSVDEIRGIFAQQAKALADAGADFLMLETFSNPDELAVAVEAAASVCDLAIVAQIAVSE
LNKTVYGKAIDEAVGQIAEMDAVTAVGLNCAVGPVGMLAGLQAIREVTDKPISIVPNAGM
PKEIDGRTMYMSTPEYMSEYAKRFFENGARIIGGCCGTTPAHIREIAKAVKAVDKAMVTE
PERRVEVHKKAEAVGQEPVPLMHRSKLGAKLARGQQITCVELTPPRGVDVSKMLEKVELC
ERYGIDAINIPDGPRASSRLSPLVAAAKIQEHADIEAILHVCCRDRNVIGMQSDMLGAHL
LGVRNLLLVTGDPPKLGEYPNATAVFDLDAIALTSVVHNLNRGLDVAGNELKGTLSMTVG
VGANPVASEMKREIDRFKAKVDAGAEYAITQPVFDTEMLFAFMEAVKDHKIPIIAGIWPF
TSYKNAEFMANEVPGVVVPDALLERMSKAKTREEGKRLGVEIAREMIEAMGHCVDGFAVS
APFGNVKVALAALGKIGIDEIS
>A0A6G7TMX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blattabacterium sp. DPU|TrEMBL
MKVTEHIAKAKKSLFSFEILPPLRGRDIKDIFYTLDPLMEFSPPFIDVTYHREEFIYVEK
DNGLLQRRTISRRPGTVGICAAIMNKYGVDAVPHLICGGFSKQMTENALIDLNFLGIDNV
LVLRGDPLKSEKNFIAQKDGHKYAVELVKQVKDLNIGKYLDKTVVEKKESPLFNFCIGVA
GYPEKHLEAPNIESDLFFLKKKVEAGADYIVTQMFFDNKKFFNFVEKCRSEGISVPIIPG
IKPISSKKQLNGLPSRFYLNIPNELVQEIEKVKDKKNIYHIGIEWAIHQSKELKNSGVKV
IHYYTMDKPENIYKIVQAIY
>A0A359H5E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotomaculum sp|TrEMBL
MKTVELFKVKTVLSFEVFPPKKTSSLDTIYKTLNELSNLSPDYISVTYSAGGSDNGESTV
EISSTIKNQYHIESVAHLTCISQTKEEVLFLLERLRVNNIENILALRGDINPDIPPKQDF
KYASDLISFIKKNSDFNILAACYPEGHIEVASIAEDIRNLKIKVENGVDHLISQLFFDNN
YFYAFLERAEHAGITVPIEAGIMPVVNRKQIERMVSLCGVDLPKKFTAMMNRYENNSVAM
RDAGIAYAVDQIVDLVSQGVDGIHLYTMNNAYIAQKINEAVKSLFISPRW
>A0A8H6ET24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dekkera bruxellensis|TrEMBL
MSMKITDKINALDKDEPFFSFEFFPPKTEHGMRNLYARLGRMSLMGPLFVTVTWGAGGTT
AEKSVDLAITCQKELGLTTCLHLTCTNTTKKIIDKALASAKAAGIRNILALRGDPSRTSE
VNKLSKEEAPFQYAVDLVKYIREQYGDYFCIGVAGYPEGHADGFYDESQDPHKDMPFLVE
KINAGADFVLTQLFFDDRSFINFDALLRSQADLKNKEIPVIPGLMPINSYDVFKRATKLA
HATIPDSVLGRFSEEIQCDDDRVKEIGVDIMTEMIEDIHQKTSVHTRGFHFYTLNLEKSI
AQIVNRSSLLSQVVDKKERELEECVSDSSDDEIDDNVTTAKRAAYMNRFKQPTNQIIVED
GKHKDSAAKTLASRQIKRRSSSQFQKIMSISSGHGALGKDATWDDHPNGRFGDTRSPAFG
SSGYGPYGPSLHVTPEKAFELWGQPETMDDVSSVFVNYLSRKVDAIPWNEMSINPETALI
QEPLIILNQHHRFTMSSQPACNCAQSADKIFGWGPAHGYVYQKAYVEMFVSKEDWKKNIL
PKLKGNPDVSYYVGDSKSYFDSSLKAKDTNCVTWGTTVVNEDSFKAWKDEGFQIWREWMM
LYPGNSPSANVLKEVLDGYYLTAIVHHDYPDEDALWDLLVGDTE
>A0A2V2C6L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MEEKNFDLSDNKCAAISYIIRGDKPSLSFEVFPPKQEGNYESVNEAVKKIAELKPSYMSV
TYGAGGSTSKHTVSIATEIKNDFGVTPLAHLTCVASNKKDIVNRLKQLQECGVTNVLALR
GDIPEGFDSDNGDYKYAAELIKDIKDFGGFCIGGACYPEGHPESGTYENDIKYLKEKVDM
GCEFLTTQMFFDNNILYNFMYRIREAGIKVPVIAGIMPVTNSKQIKRICGISGTLLPQRF
RRIVDRYGNNTLAMKQAGIAFATEQIIDLYANGINAVHVYSMNNPEVAKQIQKNISEIIK
>A0A1G0D4Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium RIFCSPLOWO2_02_FULL_57_47|TrEMBL
MSKQLFSFEFFPPHTPEGVEKLAAVRKQLAALHPEFFSVTFGAGGSTQDRTIETIRQIKA
EGYNAAPHISCVASRRENIRAMLDIYRDMGIRRIVALRGDLPSGMGSLGEFQYANELVAF
IREQTGDHFHIEVAAYPEFHPQAKSAREDILNFKRKMAAGADSAITQYFYNADSYFYFVD
ECRKLGITVPIVPGIMPIVKFAQLARFSDACGAEIPRWMRRILEGFGEDNESVQAFGLDV
VAQLCEKLLAGGAPGLHFYTLNQAAPTLAIWKRLGL
>A0A367IS15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus stolonifer|TrEMBL
MKVIDKINKAEEEGRPFWSFEYFPPKTSQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
DLTTEIVATAQSVYGLETMMHLTCTNMPKKQIDDALEAAKNCGCQNILALRGDPPKGQAN
WESCEEGFEHAIDLVHYIREKYGDYFCIAVAGHPEGHIDNPDKEDDLLQLKKKVDAGADL
VVTQLFFDIDAFIQFYKKARAIGIQVPILPGVFPIQNYTGLKRVISFNNNFVPQKIWDDL
ESIKEDDIAVKEYGINLTVEFVKKFREVGINGFHIYTFNLERSSRLVLERLGLVAPVENI
KPLPWSPSLTTKRAKENVRPIFWKNRTKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
VNLKYPVEQCLQMWGAPNTIDDIAQTFAQYCKGQIAGIPWSAQQLDAETEIIRQRLAAIN
LLGYLTINSQPAVNGAKSSDPVYGWGPKNGYVFQKAYLEFFVSPEKLDELIEKIGKDHQV
TYYAINKQGDLRTNTQHDEPNAVTWGVFPGKEIVQPTIVEAVAFTAWKDEAFELWNRWAR
IYERE
>A0A354IDN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKISDIFRTKKTVFSLEVFPPKQTSKIDTIYDTIERLSDLEPDFISVTYGAGGSGSGSLT
AKISADLKNTYHIEPLAHLTAIHTTRRQAEEILTELRENGIENVLALRGDLHPELPIPGD
FRYASDLTQFISDFGGFDICGACYPEGHPESDDLISDVTNMRPKIEAGTTHLISQLFFDN
NDFYAFLDRMRLAGITVPIEAGIMPVINKAQIERMVSTCGASLPRKFAHMVSRYENNPEA
LFDAGIAYAVDQIIDLIASGVDGIHLYTMNNPRVAHLIYMRIRKILEATNNA
>A0A349HRY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKIIDKFTEKKPLISFEIFPPKADYPIDTIFNAIDELYNLDPDFISVTYGAGGSTKDKTV
EISSYIQNRYNLTSIAHVTCITSARKEINKILISLIENNVHNVLALRGDYPKDCKISPPI
DGFKNSMELIEFIKSNSNLCVGAACYPEKHPAARSLNDDIDFLKRKMEAGADFLVTQMFF
DNDLFYDFYDKIKKKNIDLPIFTGIMPILNKNQINTILNLTGNSIPNKFKMLLEKYENNP
EALKEAGMSYAVSQIIDLLSWGVDGIHIYTMNKPSTARKILENISAIRSVLTHESKFY
>G0J642|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclobacterium marinum (strain ATCC 25205 / DSM 745 / LMG 13164 / NCIMB 1802)|TrEMBL
MKVTEYLKNADKTLFSFEILPPLKGQSLTNLLDGIAPLMDFNPPFIDVTYHREEYMYKKH
PNGLLEKISTRKRPGTVGICAAIMNKFKVDAVPHLLCGGFSKEETENALIDLYFIGVENV
LALRGDAPKLESNFVPEKDGHHYASQLVEQIIGMNHGKYLHDETEVGFQTDFCVGVAGYP
EKHFEAPSLNFDLKKLQAKIDAGADYIVTQMFFDNQKYFDFVEKVRAAGIDAPIIPGLKP
ITTLSQIVNLPKTFFLDLPDDLLTALEKCKSNADVKAVGIEWAIQQSKELIKYGVPTLHY
YTMSKADTTYKVAKEVF
>B1EQZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia albertii (strain TW07627)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPESGKPEMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A4U8YQB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoluna butyratoxydans|TrEMBL
MRVTHLYETQSPVLSMEFFPPRTEKAEEGFGAVVDDLFSMAPDYMSVTFGAGGSNRDGSY
QTVRTMLDKSIPTVAYLAGYGMAPSEIAEVLDRYRDMGIETIFVIRGDKPQQEGFTPHPD
SFSYASDLIAFIKRRYDFTLGCAGYPEGHQEAESLEKDIEHLKAKVDNGAEYVVAQNFYE
NSFFLDYVERCRTAGINVPIIPGIMPVYSVKMARILAKVCGTTITPDLEARLTSVDPDDK
EAVLAMGIDFATDQCRGLLKAGVPGIHLYTMDRTFSTMAVVKRLRDETLL
>A0A435DC16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.005.03.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFDFNPTTAYEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A3D2K9T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKISDVLQKGKGTLSFEIFPPKGDFDVQGVRSLLGALSPLSPAYISVTYSAGGSKNNRLT
EEIASMAQEENHIPSACHITVINSTNEEVENTIDSFHRRGIENVLALRGDKVDGAEGGSY
LHATDIIPSLVKKGFCVGASCYPEGHPLSPSLAEDYHYMKLKQDLGASFFVSQLCFDNRR
FFEFFKGAEKAGVTAPISAGIMPIMSKAQVNRMIFMCAVSLPGEIIRILNRYEEDKDGLL
QAGLDYAAAQIKELYDAGADDVHFYTMNRPEAAQGLVQRLKALGCLRNA
>A0A356XDQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MFREKVLSAQPGILTYGITPPKKDNTPEKIAGITQRHIERIRSLPIDALIVYDIQNEAER
NGSERPFPFLPTLDADVYVNHYLGELKIPKIIYRCVGKYSREEFTSWLGSARESDNASVF
VGAAASGQKVRLKLSEAYGLYQQIHPNLLLGGVAIPERHIRRTDEHARIREKMEKGCRFF
VSQAVYDVAASKNFLSDFYYHCKESGIGLVPVIFTLTPCGSARTIEFMKWLGISIPKWLE
NDLVNAEDILGESMDFLMEIAADLTAFARGKGIPVGFNIESLSIRKAEIDASVQLALDIK
KMLQPG
>A0A428ZQI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC 01420|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVHAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PDALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A257Q6X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidocella sp. 20-57-95|TrEMBL
MTHSPPRDALERWVTGDRVMPLPGRANTGAPAISFEFFPPKTPALETQLWACIERLATLQ
PRFVSVTYGAGGSTQERTHATVVRLVQETKLIPAAHLTCVGATREEVDEVARRYWDAGVR
HIVALRGDPPAGQAYAPHPGGYAFAADLVAGLKRVADFEITVAAYPEVHPQAESEAADLD
NLKRKLDAGATRAITQVFFENSNFLRFLDKAVAAGITAPIVPGIMPVSNFTQAAKFCTAC
GTIVPTWMADLFEGLEDDAETRRMVAAATAAEQVRILQANGIDEFHFYTLNRPDLVYAIA
RILGVKPAAV
>A0A2V2D916|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MIAQLLKDGKQTLSFEVFPPKKEEEFENAQAVLNSLAELKPDFISVTYGAGGSRSKKTVE
IASYIQNTLRIPALAHMTCVGSKKEDIDRVADSLRQADVSHVLALRGDRPAWMDDAQFES
RDFAHASDLTRYLKATTGLEIAGACYPEKHYEAPDPETDLEGLKKKAQAGASFLITQLFF
DNEVFYRFLERKGTAGISLPVCAGIMPITSAKQLGTTVTLSGSSIPKELADLIAAYGDQP
EDMRKAGVDYAVRQILDLKAHGADGIHLYSMNRPKTTREIVEAIR
>A0A0R4J8A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain AYE)|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLDKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A1H6TPM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sharpea azabuensis|TrEMBL
MKIIDILNQDKITLSFEVFPPKLTKNYDDVAFKAKEIAKLHPDFMSVTYGAGGGTSEYTL
NIAKEIKEKENVEVMAHLTCVSSSKEHVHNMIHRLKENHIENIMALRGDIPSGGSKFHDY
QHASELIKEIKASGDFCIGAACYPEGHPEAGNKDTDIKNLKKKVDAGADFLTTQMFFDNN
VFYNFLFRAREAGIDVPIVAGIMPITRGLQVKRARELSNCSMPQRFISMVDKFGDNDEAM
KQAGIIYASEQIIDLIASGIKHIHVYSMNKPDVACAIMHNVSEIIR
>I0BDN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus mucilaginosus K02|TrEMBL
MNSGRKDEPPGSGGQQMLKEKIQGRKPGIITYGITPPKQNHPPEKIAEIAKKQIDRIADI
GIDGLIIYDIQDEADRIDQERPFPYLSTVDPTTYSKEYLGPLTVPHIIYRSVGKYSESEL
SGWISSDPGQNRFSVYVGASSSKQEVRLSLPQAYELSRHLNDTLHFGGVVIPERHLTRKD
EHLRMISKMNSGCRFFVSQATYDVEASKNVLSEYYYTCQEQGLEMVPILFNLTPCGSLKT
LEFMKWLGISVPKWLENDLMHSNDILDKSVRLTLKIMEELMDFGLEKGIPIGCSVESVST
RKVEIDASVQLLKDVKQSMENRLLQPQSL
>A0A1I1EXV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp. OV174|TrEMBL
MNLPISFEFFPPKTPEGAQKLQQTRQALYAHQPEFCSVTFGAGGSTQEGTFGTVKEILEE
GVSAACHFSCVGATKATVRQQLAQLQAMGVKRLVALRGDLPSGYGMGGEFHYASDLVTFI
RAETGNAFHIEVAAYPEIHPQAKSADADLQAFATKVRAGANSAITQYFFNADAYFRFVDD
VQKMGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVI
TDLCEQLSQAGVPGIHFYTMNQAAATTEIIRRLTPA
>A0A6L7SY17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTTHEQSVQKLVAGFSTEVTPGSAAKIGSFRDHLREGTTVYITFLPGSDFADTVKVAKRL
REEGFEPVPHFAARSIASKAALNDYLSRVVGEAGVDHVLCIAGAVSNPVGEFTDSMQILD
TGLFDQHGIRQIAVAGHPEGSPDMSDEAIMAALHWKNAYSQKTDARMYLVTQFVFESGPI
IRWDQQLQQEGNTLPIRIGIPGLATIKTLLMHARACGIGPSMKYLTRQAKNITRLMTINT
PDVLVRELGVHSASSQNSGIVGIHMYPLGGLRRSAVWSYAVADGLFELNSKGGLDVGVDY
S
>A0A7C1ZA02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MHSQKKYTPQFSFEFFPPKTAEGEKKLRVTRDELAKLNPKYFSVTFGAGGSTRQGTIDTV
LEIQQAGLSAAPHLSCIGSTKENISKILNLYRENNINRIVALRGDMPSGMQETGEFRYAN
ELVEFIRKESGDHFDIEVAAYPETHPQAHDAQSDLVNFKRKVDAGANSAITQYFYNIDAY
FMFLESCEKAGIDLPVIPGIMPITNYTQLARFSDMCGAEIPRWLRKHLQGFGDDRESIKA
FGEEVVTRMCEKLLAAGVPGLHFYTMNQSAPSKAIWNNLGIKTSNK
>A0A510NYK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida auris|TrEMBL
MSTVTSKIRSLAPGERFCSFEFFPPKTDAGFRNLLARLSRMMALNPLFLTVTWGAGGSTA
EKSLDLAATCQKELGVTTVLHLTCTNTNKEIIEDALQRARAAGIKNILALRGDPPRTEEY
WTPNCDFSSAVDLVRFIRQNHGDYFCIGVAGYPEGHVEGADASQQDPRKDLPYLVEKIEA
GADYVVTQLFFDVDKFVAYEKLLRETPQLKNVILIPGLMPITTYRVFVRATRLSHANVPR
DILSKLDAFANDDDTVKTIGLDVLTKMISEIDQRTEGRIRGYHFYTLNLEKAVASIINRS
PVLQNMISHNKSVEHDDAVASDSDEEFAPPMKNGRRKSSVNENQVAVPDDAKRALVSKAL
SKDPKSIVDISTGKGALGKDATWDEFTNGRFGDSNSPAYGEIDGYGPNLKLHTNKEVEET
WGNPESTADITRIIVDYLSNKINVLPWADSELSPETGLIQEELFELNERGWFTLASQPAV
NNCKSSDKILGWGPPNGHIFQKSFVEFFIPKKQWKDELLPRISKQVEEKTITYYCGDASG
HISSNLPIGKGKDSNTKSAVTWGVFPSKEVLQPTIIDYESFKAWNEEAFLLWLEWARCYR
KDSKSYQLLNDIYNNYYLVSLVHHDFTDEFVLWTTLLSD
>A0A7H8SF35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NEB 394|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVSLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A6P1ASG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium LRH843|TrEMBL
MGLLERLAAGVLIGDGAMGTLLYEQGIDQCFEEINVTDPVKILDVHKRYVSAGAEVIQTN
TYAANRLKLEKYGLENDVKRLNQAAVRLAKQAADDQAFVVGTVGGIRRFSLDEWSLKEIE
RAFADQLDALLEEDIDGLLFETFYDLEEANLVAKLARKQTDLPMIVNLSLGEVGVMNDGV
PVADAFEQLVTNGVNVTGLNCRMGPFHMLRSFESIPLLSESYLSAYPNASLPDYRDGRVF
YQSNAEYFKAMGEKFILQGVRLLGGCCGTTPDHIAAFAGARKKVAPVESKTVRPIIKQIR
ETVIVSRKQQTLPELVKSRKSVIVELDPPKKLNTKKFMDGAKALKEAGVDAVTMADNSLA
SPRVDNLALGAMIKEQIDARPLIHVTCRDRNLIGLQSHLMGLHALGIDDVLAITGDPTKI
GDFPGATSVYDVTSFQLISLIKQLNEGVSFSGKELGQRANFSVGAALNPNVRQIDKAVKR
MEKKIESGADYFMTQPIYDIEKIEALYHETKHIDEPIYIGIMPLTGTRNAEFLHNEVPGI
KLTDDVRAAMAACGEDPEASIREGIQIAKSLIDAALTYFNGIYLITPFLRYEMTVELTRY
IEEQKAMVSLK
>A0A7X6RHK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia veterana|TrEMBL
MSFDNVRGRSTPGRPSRTPSGTPSVVGQLRRRPDGGIPFSVEFNPPRDAAAEARLWRAAR
EFERMHPAFVSMTYGAGGSTRDRTARITGQLARETTLLTVAHLTAVGHSVAELRSIVGSY
ADAGIRNMLVLRGDPPGDPLGEWRKHPEGVEYAEELVRIVCGLGDFHVGVASFPQGHYRS
PDLDHDTRYLVAKLRAGAEYSITQMFFDVEHYLRLRDRVAACDAEQGAKPIIPELMPITS
LRTVQRAEELSGRALPAAVMQRLERAAGNDPEANRNAVRAVGIEIATEIAQRLIDEGAPC
LHFITLNFAKATTEVLTNLGYTVTPAAVSA
>A0A6N9CU10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDFPLKTLRDALRGKDFAVVGQLRLHQDHGRDDLIRQAECLSPVVDAVAVTDNPYGLVHM
SGLAAASILLQRGIDPVLQISARDRNRIALKSELLGAAALGVTSLVLQRGNKLPKDGQPQ
VKEVFDTGAKKFLAAAKQLSSFQVAQGSPELFLGTMVTVFDPDDGWQPTEIKAKVEAGAQ
FVQTQACLNVALLRRYMKFLVAAQVARRCHVLVSVPVLTSVESARWLSANHRGAVVPDRL
VGQFKRAKDPESFGIALCAE
>A0A521REW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNAQTATQTATPNPQLKSGSNLEKVLAAGHFAVTGEIGPPKSWRAEVIRKKAGLLKGCVD
AANITDNQTAIVRMSSIATGIIVMQEGLEPIIQVTCRDRNRLAMQSDILGAAAHGLKNVL
CLSGDHQSFGNHPGAKNVHDIDSMQLIRMFRDMRDSGLFQCGEAITDGGPPLFIGGAANP
FADPVDLRPLRLKKKAVAGVDFVQTQLIYDMDRFREFMKKVVELGITEAVSVLAGVGPLK
SAGMARHMRDNVPGMRVPDAIVKRMEGAVNGIDKDDKAARNAAWRAEGIKICIEQIQEVR
EIPGVAGVHVMAIEWEEAVRSIVEGAKLLPRPVLA
>A0A2A6HK15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. L43|TrEMBL
MALNNEVRGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKDETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGNFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRSAGISIPIVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGLNEFHLYTMNRAPLVSAVLDNLGLSRRAAKSAGAAA
>A0A2D8QUP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSLFKEKLTEGDFVVTSELTPPKGIDIRKMLTTAEQLKEYVDAFNITDSHNARMSLSPLA
AAHALIRAEVEPILQMTTRDRNRIALQSDMLGAASLGVQHLVCMGGDPPHLGDHPDAKPV
FDFSTEALISAAAGLAMGKDSTGNELNEAPELNVGAVVNPGADDLDTEITRLEKKIESGA
TYFQTQAIFDPAAFEAFMNRVMSFQVPIIAGILPVKSAKMADHMNKNVPGIDVPETIVQT
IEAAEDVKSVSADISAEIIREIRPMCQGVHIMAIGWEALIPTILEKAK
>A0A351CJT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKESIKINPEFIYHPGNPLPEIEGHVSCGRFERILKGGDFAVTTELAPPDSADRTEVFHR
AAMFNDVVDAINATDGSGANCHMSSVVVCALLSHIGYSPILQISCRDKNRIAIQGDILGA
AALGISNVLALTGDDVSSGDHPEAKRVFDLDSISLLTTIIKMREESSLLSGRKLKEPPRM
FAGSTINPFVPPIKSRVLQLEKKIDAGAEFIQTQYCFDMPMLVDFMAKAVDKGLTERAFI
LPGVGTLASAKMAKWLRKNVPGVHIPDSIIKRLECANDQKKEGQKICTELMQKVKEIDGV
SGVHVMAYGQEKYVAQMVKDSGVLGDRKPWAPMNRY
>A0A3N2P9B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. HM5-17|TrEMBL
MALGLPSVFPGSRPSIGDLVRGPRPTFSFEFFPPKTERGERLLWQTIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRHVIGRLAEAGVRNVLAVR
GDPPGDPTGEWIPHPQGVRYAEELVRLVRESGDFSVGVAAFPYKHPRSPDIATDTKYFVR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPIIPGVMPVTQIGTIERSQQLSGAPF
PPALAAQFERIADDPEAVRQLGIQQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLQ
VGVRA
>A0A351D186|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTNKPEISLEFFPPKTEQGVANLNDARSELDALAPSFYSVTFGAGGSTREGTYDAVKSII
DAGGDAAPHISCIGASKKSIRELLEGYSAIGVKRLVALRGDRPSGMVELGDFAYANELVE
FIRAEMGDRFLIEVAAYPEYHPESSDPATDLANFKRKVDAGAHSAITQYFFNADAYFALV
DSAMLANIEVPIVPGIMPITNFVQLARFSDMCGAEIPRWLRSRLEQYQHDADSLQDFGAE
VITTLCDCLLEGGAPGIHFYTLNKASPTIEICKRLELI
>A0A349X5J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNTVQLSFEFFPPRFDGTTDNLVKHYKELASLKPKYVSVTFGAGGSTQLGTLGAVKALQA
AGANAAPHLTCIGTSKAYVKEIMADYLAIGVDRVVALRGDYPSGMVSKGEFNYAVDLVRF
LRSEYGQDLTIEVAAYPEFHPESVSPSQEIKHFKEKIDAGANAAITQYFFNADSYFAYMD
DLNRAGVIAPVVPGIMPIDNVAGLRKFSGMCGAEIPKWICNRLNQYENDPESLRSFGLDV
VSHLCLDLIENGVDGLHFYTLNKSALVKQICANISGSHQQ
>J1S1B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces auratus AGR0001|TrEMBL
MRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTADLRNIIGQYAGAGIRNMLALRGDPPGDPMGEWVKHP
DGVAYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVDKCRAGADFAITQMFF
YPEDYFRLRDRVTAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQQS
>A0A2E8J4W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MRRKENAKKGSPINRFLSQEVKQALAESMREAYMEIFPTGTIESRLDVLEQGSYVAVTCS
PTKGIDETLDMSERLAERGFKVVPHVAAKMVKHKTHLKEILARLNDLPIISIFVPGGDAL
KAVGDYSSALELLRDLAEFDHNFSEIGIAAHPERHPVISNEVLLDQLIKKQEYSNYLVTQ
MCFDAEIIVNWIREIRGHGVTLPAWIGLPGVSQRGSLMKTSIRIGVGDSLRYLKNHGRIA
AKLLMSKEYRPDDLLTNLAPYLADPYYNIEGHHIYCFNAVEKTEGWRKEFMDNI
>A0A1N7BQJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. B10|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETADHFHIEVAAYPEMHPQARNYEDDLANFVRKAKAGADSAITQYFFNADSYFY
FVDRLQALGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTRSIQSFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A2D7EX72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MVNQHLSFEFSAPRNPVETKKLLSVYKRLKVFSPEFFSVTYGAGGSTKDGTKDAVLNIQK
LGSSVAPHLSFGGDTSEKIEALLQDYQKADIRRVVALRGDIPSGQMTKMTFASELITFIR
NKTGSHFHIDVAAYPETHPDSPSVESDIKFFKNKVDAGANSAITQYFYNADAYFRYIDKC
ASHNIDIPITPGIMPITNYNGIIRFSKNCGAEIPRWILKQLDSYKDNPDSLKAFGLEVVT
ELCSRLLEGGAPGLHFYTLNQSLPSARILRNLNAQ
>A0A2D8DLF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGAPLRCRIMNISLEFFPPANLDFNALLSEYKKLEHLDPSFVSVTYGAGGGAENKSLELI
KVLKKNDLDIAAHITLVNKSIDDLEKIVSDFEKLGVKKFVALRGDSPEGKFKQHPSGFFN
TSDFVEFLNNKNFEVIVSAYPEPHPDSKGFDFDLQLLKNKSASGAKKAITQFCFSKDDYE
KLIETVLKENIEVEVIPGIMPIYNIENITRMAEKCGTKVPSNIINKFGDDDVSNQKYAIE
ICNDQLDYLSELGCQKFHFYTLNKSYLINKIFRERSLL
>Q60CG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)|TrEMBL
MGSAMKTQLKYPREFSFEFFPPKTEEATENLRRTLTKLAPLKPRFCSVTFGAGGSTREKT
FETALEIQQTTGIECAPHLSCIASTRRSIREILEAYRSHGIRHIVALRGDMPSGMLSAGE
FRHANELVEFIRSETGNHFHIEVACYPEVHPQAASAESDLKNFKRKVDAGADSAITQYFY
NPEAYFRFVDDCERLGIDIPIVPGIMPITNHSQLVRFSDLCGADIPRWIRKRLEAFGDDR
KAIRTFGLEVVTELCRRLLEQGAPGLHFYTLNRAEACLEVWKALGLEPA
>A0A349KRP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MEARNLQILSELVADGSIELIETSTEVIHPGQELLPYAMSVFVPALAKRELMSNLGRLQS
LSQEGFSPVPHVAARRLSSEAQLREFLSRAVEDCQVRRVLLIAGDERDPKGPFTDILDVL
DSGILQACGIEEVSFAGHPEGHALISHQVLQEALAKKLAWASDAGMGASVLTQFSFTPAR
IIQFCATLEEEAPGVPVYVGMAGPTDIVSLMRYARLCGVSTSLRALQSLGIKAAKLVMHT
DPTEQLQLLAHHCATHAANNIIGIHLFTFGGFSSSAKWMHNAIVGAAPPTRVSQGN
>A0A534D2Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
DISVAAYPEVHPEARSAAADLDNLKRKIDAGATRAITQFFYDTSVFLRFRDALAAAGVHA
PLVPGILPITRFPQVRRFAERCGASIPRWLHERFAGLDDDQDTCRLIAASVAIEQVEALR
RHGVRDFHFYTLNRAALTYAICHALGLRPLARAAGAARQEALG
>A0A2E5DBY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSQPQISYEFFPPHTKAGITKLVETAQVLAATDPAYFSVTYGAGGSTRTRTYETVVKLME
XGMTMAPHLSWGSDSESTVVSXLDKYRELGVXRXVALRGDXPSGIGSIAPIRRAHSLVDL
IRRRFGDTFIIHVAAYPETHPDALSPEDDIRFLRKKIEAGASDCITQYFFNADSYFYFID
RCQAHGIETPIVPGIMPITNYEGLVRFSDGCGADIPRWIRTRLAHLVDKPEDLLAFGIEV
VTNLCERLLNGGAPGIHFYTLNKPVASAQIARNLGLG
>A0A2S8WPF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. MYb227|TrEMBL
MSIAASAAPPSLSYELYPPVNRAASESIFKSIEALESTDPDYVSVTYSGTHTRRRASLDL
IEHLIQNTRLRPLAHLTCVGESKQSLENLIRHFISLGVRGVLALRGDLPTDPDGWRGEFP
FARYLIELIREVETDHSAALAGGRLGVGVAAYPIQHPESPSFDHDVEVLLGKERSGANYA
ITQVYFRPEEYTNLVIAARKAGVSIPIIPGVIPLSSPKRFDRLASMVGVAPDPLLAHALE
TASSDAERHKIGVNAAANLAQRAFDDGAPGVHLYTFNDHRGSLDVIEKLELPRTRALANN
MWAERAAV
>A0A2E0WN50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTQQKYDKSFSFEFFPPKTEEGAKKLRLARSRLDKLNPNFYSVTFGAGGSTQEGTYETV
AEIIKSGGDAAPHLSCIGSTRDNIRELLQRYKDAGVRRIVTLRGDMPSGMRDTGEFRYAN
ELVEFIRAETGDTFKLEVAAYPEFHPQAPTAFEDLKNFKRKVDAGANTAITQYFFNADAY
FRFVDDCEKMGIDLPIVPGIMPITNYKQLARFSDACGAEIPRWIRQRLIAYGDDMESLGK
FGEEVVSDLCRRLLDAGVPGIHFYVMNRSAPTIAIWKNLGLPIQD
>A0A661BRY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKSQKKFTKKFSFEFFPARTPEAVVKLETTMGRLAKLNPDYFSVTFGAGGSTREPTFETV
KNISEKTSIEAAPHISCIGVMTDEILEVLETYRSIGIKKLVALRGDLPSGSAGGYGQLRY
ANELVEFIRKETGDHFHIEVAAYPEFHPQANNASEDLSNFKKKVDAGANGAVTQYFYNPD
AYFRFVDSCEKLGIDIPIVAGVMPIINCSQLVRFSEACGAEIPRWILKRLQEFGDDRTAI
REFGIDVTTELCDHLLSGGAPGIHFYTMNQSAASEAIWNNLNLSDIDRNLT
>A0A2E7LJJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKFKDSMYDNFSFSADLNLAAVGSVEDLLGQARILSRSVDGIHVSDGANDGVHFPALATA
QLLLQNDIDPILQISCRDKNRPTLEIEIRGALALGVTSVLLVRGESGGISDTSDRIVKVS
TTELIQMVRRIEQESQQANLSVGTIATVFKPAADWRPQALLKKTGAGANFIRTQLCFDAD
KLKLYMPKLVRSKVTWKAPIIVNLAVLPSAKAAKWLSENLRGSLIPETVIKRMEHAVDPE
AEGVQVAAELIAEFNTIPGISGVCLMTPGPPELIPEAVNASGLRQD
>A0A661FMS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTNKNKADLFSFEFYPPKTEQGVVNLQKVHRDLARLNPDFFSVTFGAGGSTRDKTYDTVV
NIQQSGVSAAPHLSCVASTKENIREILNNYREHGVSKIVALRGDLPSGMMSAGEFRFANE
LVEFIRAETGNHFQIHVAGYPEVHPQADNAVEDFNNFKRKVDAGADAVITQYFYNAEAYF
YFRDKCEKSGIDIPIVPGIMPITNYAQLFRFSDMCGADIPRWMRKTLECFGDDKASIMAF
GEDVVTKLCQELLDNGAPGLHFYTMNQSGPTLAVWDNLQF
>A0A6G2VGU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID161|TrEMBL
MNPALTGSPEDTAPRPHGAVSQGRGARLLDDFSLEMTGKDVARLEEAGDTIPPGTRINIT
FLAGEDTTTRLTAARAVKRLGFVPVPHISARRLPSRPALEEFLGGLAADGTAENVFVVGG
DPARPEGPYEDALSVLRTGLLHRHGVRHVGITGYPDGHPGIADHALWTALADKAAAITAA
SFAGDVITQFGFDVDPVLAWLEDLRARGVHLPVRIGVPGPAGVRRLLGYATRFGVGTSAS
VARKYGFSLTNLMGTTGPDRFLHALAERCDPARHGVVKVHFYTFGGLRTTAEWITGFRQR
NTFAPPAP
>A0A806LFD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei N1115|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A7L9L4R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>A0A4W2GGC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos indicus x Bos taurus|TrEMBL
MVNEPRGNGSPGPRWEGSSSGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKH
IRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIDNDAAIRNYGIEQA
VSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDV
RPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWG
EELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTI
NSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVD
VKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEE
SPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>A0A1J7IRV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coniochaeta ligniaria NRRL 30616|TrEMBL
MDKVTDKIAALPPGTDYFSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRRLIDQALQDAKALGIRNILALRGDPPRRSE
YRELNDPEPEDGEDEFVWAVDLVRYIRKTHGDYFCIGVAGYPEGHADESHPLGQSLEHDL
QYLVEKVAAGADFIMTQLFFDIKAYDHFETTLRKHPSGVFKDIIIIPGLMPIQSYQMIKR
TTKLSHAQMPDAVMDRLDAVKGDDEKVKMVGVEIVAELVENIREVKSRTSSGPKGFHFYT
LNLEKAVSFIVERTNLIPPSTPFEDEGAIADELPPTAIPELHVNGSSSSQILSLKNMSRR
QSSVGSDPRNRVIVSGRSGLSNPDYEATALDASIPAEPVNTRANTLAISEGEGVLGREAT
WDDFPNGRWGDARSPAYGQIDGYGVSLHVSVAQAINLWGTPTAPEEINQLFIRHLRGELS
AIPWSEEGFNAETAAIRDQLVRLNERGWWTLASQPAVNGLKSSDETFGWGPANGFVFQKA
FVEFFIPARDWTALEKKLTRPGMRDTVCFYAINARGDFVSSDTIPSSSGEGSNGDGEAAA
REEGVREPSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFSIWGEWAKVYGRGSESQK
LLDRIREQSWLVNVIHHDFVHKDALWDLLLED
>A0A455X271|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrotoga sp. AM1P|TrEMBL
MTNSRSFSFEFFPPQTQEGANKLAAARKQLALLKPAFFSVTFGAGGSTRERTLETVQQIQ
ADGYEAAPHLSCVGSTRENIRAILHTYKNMGIKRIIALRGDLPSGMATSGEFHYANELVS
FIRVETGEYFHIEVAAYPEFHPQAKSPRDDLLNFKRKVMAGANSAITQYFYSADGYFRFV
EECRKAGVTLPIVPGIMPIMKFSQLARFSDACGAEIPRSIRKILESYGDDTESVQAFGLD
VVTQLCERLLAGGAPGLHFYTLNQSAPSLEIWKRLGL
>A0A3D8HZ46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. MIT 99-5507|TrEMBL
MFEYIESVVEKIHSTSPFFSLEINPKLSAKLQDKNINELKSFDSIDAFVVTDSPLARFKP
SSIISSIKLQNILQKPIICTLSMRDRNSIALCGDILAANELGLRLFLTLTGDGIKNSDCE
YVKGVFEGTSNKLATIIDDLNNGIAINKKKLIEKPQKIYYFAVINSYANNLQSIKKRMIK
KLSNNNISALYSQPVFSKDRAELLLSNINEANALYGTNTALVLGFFAITSYKTAVFLRDK
LPGIYIPDKWIESLYKASQKGVQEEQKVGLELSLNLFSDLKTIHNKFHLMSRQHSILKHF
I
>D2S7Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / KCC A-0152 / KCTC 9177 / NBRC 13315 / NRRL B-3577 / G-20)|TrEMBL
MCVEVPGGARAPTGTGPPPPVERRPTSRRSRGTLERALREASYEVLPLRGAEASVVEHVP
RTVPLTVTVTEAKGLTPTLELAERLSGHGFTVTPHLAARLVHDASHLADVIARLQAAAVD
GVFVVGGDAAEPAGTFPDALGLLEALETVGHHFRHVGIGGYPEGHGHISAELIERALERK
APHATHVITQLCFHPASTTAWARQVKRRGVDLPIRIGLPGAVTRQKLIRISAGLGLGRSA
RFLAKQHSMFWRFFLPHGYRPDRLVEGLAPTLGRPEHNLQGFHFFTFNEVARTEAWRQEW
LARLSDAAAG
>A0A1E7KCK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces oceani|TrEMBL
MALGIQSTRTDRPPTVRELLASGEESFSFEFFAPKTAKGERTLWDALRRIEAVSPTFVSV
TYGAGGSSREGTVTNTERIATETTLTPVAHLTAVNHSRTELRNVIGQYADAGIRNVLAIR
GDPPGDPMGEWVLHPDGIEYAHELVEMIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVN
KCRAGADYAITQMFFNVDDYLRLRDRVDAAGCRTPIIPEIMPVTNANQIERFAQLSGATF
PPELRDRITAVQDDPAAVRSVGIEYATEMCAKLLNEGIPGLHFITLNHSTATLEIYENLG
LHRRSRD
>A0A0J9X8D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geotrichum candidum|TrEMBL
MSTVKELIASLKPDETFFSLEFFPPKTKTGLENLKARIQRMTCLGSLFVTITWGAGGSTA
EKSLDLAQFAQKQGNTTCLHLTCTNMDKEILDNALKRAKDAGIRNILALRGDPPRGEEYW
QANTDSQFNYAVDLVKYIRKNHGDYFCIGVAGYPEGHTDGVDTSGQDPRNDLPYLVEKVE
AGADFIITQMFYDVDKFLEFEQLLRNHSSPLLQKIPIIPGLMPINSYQSFVRASKLSHAT
IPPALLDSFNAIPKGDDERVKLLGVEVLSNIITTIYQKTGGRVNGFHFYSLNLEKSVAKI
IEQCPIIHIPSSSTNIAKTKTRASFSSISSSGSAAISEGDDSEFVIEPPAPGTVRAHRKS
SVNAHNRLIVSDLKGSGNSSFLTVTESGVTPASDIKSQLPDDILAISTGEGALGREANWD
DFSNGRFGDSRSPAFGEIDGYGPSLHVDNKKAYKIWGYPVDPQDISSIFKRHIMGQLDAI
PWSDQPLDAETMLIQEELLNLNDHGLFTIASQPACNAVKSSDKIFGWGPPNGRVFQKPFV
EFFISPKQFEKLESIIAAKNKEEGDIYSYYAATSNGKLITNLPSGSSNVVTWGVFPNREI
LQSTIIEEESFSAWCEEAFSIWREWQRLYTKKSASYKLLDNIYDTYYLVTILSHDYMNNN
SLWETLLDV
>A0A640SG03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces caniferus|TrEMBL
MRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALRGDPPGDPMGEWVKHP
DGIGYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVAKCRAGADFAITQMFF
YPEDYFRLRDRVSAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQQS
>A0A4R4NEQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea longispora|TrEMBL
MAFELICEIEPPTKPDMKHVRHQIGTMSKVAHTFLIPDNHIGRATVSSVAVAHEVEAMGG
RGIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPASGNRTSDLTVRSMIEEAREF
SPGSRLGAAAGLRPLPAWKRAADFLFLQVSFSVEAQLRWREAHPVDAPVYAGVMVLASAG
HARSLATTIPDIALPDALVEQVTGDRQAGVEAACEQVLALRDSGAFDGVHLIPVSRYRDV
ERLLAPALG
>I7DZL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter inhibens (strain DSM 17395)|TrEMBL
MTTPDISFEFFPPQSLEASFRLWDTVQTLAPLAPRFVSVTYGAGGTTRDLTREAVATLHN
SSGLNVAAHLTCVNATKSETLAIADQFAEAGVREIVALRGDPPKGAAGFEPHPKGYANSV
ELIAALAERDQFSIRVGAYPDRHPEATSARADVDWLKRKLDAGADEALTQFFFEADTFLR
FRDDCAKAGIDTSRITPGILPIENWKGARNFAKRCGTTIPAWIDDAFDKAIRDGREDLLA
TALCTELCSDLMDNGVDKLHFYTLNRPELTRDVCFALGITPDVSLENVA
>A0A446ZJQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus|TrEMBL
MSHVSLCFQQNQFFVLVEYLTSLHEIYPVKHELAGYPAAMTLADRVHSDHDVAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRNGQPRTRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIDAL
KQAKSFLTKYGYLQQILACVMPLTLGRANFMVKHKVAGIVITAHMLKVLADEKLAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELDSLEQLWNSLWQVT
TGKEFSPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENTLVAK
VLLKTEVLSKYSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSIKARLAKAVEQTEILKEKLIPTVPLETRGTSSWKNWYLATL
>A0A0H3HQB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei (strain 1026b)|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A7L3X3H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atlantisia rogersi|TrEMBL
MVNETQQTCSASSSSKSDAGSSSGSESSKDSSRCSTPILDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDEITAHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFEDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLR
FMKDCQGIGITCPIIPGIFPIQ
>A0A7C7ZLK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cycloclasticus sp|TrEMBL
MALESHQPISFEFFPPKTEEGREKLLAVSKKLGQLDPAYFSVTFGAGGSTQQGTINTVLD
IKKQGFSAAPHLSCVGSTKENIR
>A0A1A0GNV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus|TrEMBL
MSHLSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPESIDKVLHFSGKARDIQDFEHFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMSAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIGAL
KQAKSFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILMCKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELKVLEELWNSLWQVT
SGKEFSPEITHFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGLGRFIFKASFWENALVAK
VLIKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKEKLIPTVPIETRGTSSWKNWYLATEA
>A0A852PNU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atrichornis clamosus|TrEMBL
MVNETQHACSASSSSRSDGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDHLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A0Q6L3M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. Leaf278|TrEMBL
MVDRLRSEPDARIPFSVEFSPPRDAAAEARLWRAVREFEQLAPAFVSMTYGAGGSTRDRT
VRVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRGITNILVLRGDPPGDPLGDWE
KHPDGVEYAEELVRLVRDLGDFHVGVASFPEGHHRADDLEQDTRCLVGKLRAGAEYSITQ
MFFEVDDYLRLRDRVSAYDAEQGAKPIIPEIMPITSLRSVRRMLELSGTTLPSSLDEKFT
RAAGSGPEEDRAAVREVGIELATNIGERLISEGAPGLHFITLNFARATREVLCNLGLAPA
RV
>A0A2G5EVK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquilegia coerulea|TrEMBL
MKVIEKIREAEAENRVVFSFEFFPPKTDDGVDNLFDRMDRMVQHNPSFCDITWGAGGTTA
DLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQDK
FVQIEGGFACALDLVKHMRGKYGDYFGITVAGYPEAHPEVIDSSGVATLEAYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPIGNYKGFMRMIGFCKTR
IPAELTAALEPIKDNEEAVKKFGIDFGTEMCKKILAHGIKQLHLYTLNMDKSALAILQNL
GLIDEAKISRPLPWRRPTNIYRVKEDVRPIFWANRPKSYLTRTIGWDQYPHGRWSDSGNP
SYGALTDYQFMRPRSRDKKLQEEWAVPLKSVEDIHERFAQFCLGKLKSSPWSELDGLQPE
TKIINEQLENINLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFCSQDQLT
ALLGKCKDFPSLTYLAVDKKGNSMSNVAPTDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFEIWTKVWAHMYPEDDSSKSLLEKIQSSYFLVSLVDNDYINGDLFAAFKEL
>A0A2S9QHM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labrys okinawensis|TrEMBL
MTIDTRLPHPDDFGPHPAAPLPELPGHTSRGRLERVLRRGEFAVTAELNPPDSANPDDVL
ERVKPFEGWVDAINATDGSGANCHMSSVAICALLTRVGYSPVFQISCRDYNRIAIQGNVL
GAAALGVCNVLCLSGDGVQSGDHPEAKPVFDLDSTALLSTIRTMRDEQRFLSGRKITTPP
AMFLGAAANPFVPPYDFRPINLAKKIQAGAQFIQTQYCFDIPLLERFMARIRDMGLHEKC
FIMVGVGPLASARTAKWMRSNVPGVHVPDDVIKRLEGAQDQKEEGKRLCIDIIQQVREIR
GVAGVHVMAYRQEEYVAEIVHESGVLAGRTPWRRDMAPSPIPHEEIVATP
>A0A2S8VJE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp. MYb9|TrEMBL
MPDSMSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGATRQDLRDILQAYKNDGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVTKVNAGADAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPLAVWKELAL
>A0A5C5TX37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas wenzhouensis|TrEMBL
MTAISFEFFPPKTDEQRAQLDRTVARLARHRPEFVSCTFGAGGSTLSYTADTVRHLLQRH
GLDAAPHLSCVGGSCDEIAALLDEYRELGCRRIVALRGDLPSGMGQPGELRYASDLVAFI
RKRHGDHFRIEVAAYPETHPQADDALADLRHFRTKVHAGADSAITQYFYNADAYFHFVDA
VRALGVEVPIVPGIMPISNFSQLRRFSAQCGAEIPRWVEKKMQALGDDVEAVREFGADLV
AKLCRRLVEGGAPGLHFYTLNLARPTQAVLARLQ
>A0A7U9GVG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens R124|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A165YTL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibularhizoctonia sp. CBS 109695|TrEMBL
MKITNKIDAASKADRIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSEMVKTCQSMIGIETCMHLTCTNMPKEKVDIALKEAKEHGCRNILALRGDPPQGKEE
WEAGEGCFVQGIDLVRHIRKLYGDYFDIAVAGFPQHQLLPPAELAQELAWLKEKVDAGCN
LIFTQMFYDVEVFFDWVKSVRAAGINVPIVPGIAPIQTWNGFQRATSLAKTVIPKSFSDA
LEPYQNDDEKVRAIGIKLVADMCRRILDADIGIRGLHFYTMNLEKATRLLLEELSLVPRV
ETIKPLPWRQSLTPSRRDENIRPIFWANRAKSYVHRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEEGVKLWGEPTTFAEIRGLFSRFCTKELTALPWSDQAPATETGVIATQLA
KMNDYGFLTINSQPAVNGARSDDKVHGWGPSNGYVYQKAYLEFFVSPELLDKLLVHIERD
PSITYYVLNKAGDLRTNTHSEGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAYELGQQ
WAQIYDANSPSRKLICNLMETSLLVNIVHNDFQSLDAIFQPFFKAGAEYAAENPPTLNGA
TANGHAN
>A0A5B8KDW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MPETDDGPDSSAKQALMARYSIEITPKDLPALHEVKSDLPPGTAVSVTFLAGDGLDCRLN
AAVDARRLGFVPVPHLSARRLRSAFELEEYLSKLAAQARIDQVFVVAGDAAQPAGPFKDA
AAIIGSGLLGKYGVRTIGIAGYPEGHPDFLAEVLWQAMAQKHALIADLGHSCEITTQFGF
NADPVLAWLRDLRERGFSSPVRLGVPGPASVKTLLRFATRCGVGASTKVLAKYGMSITRL
LSTVGPDAIVTEFVDRLDPKVHGEVRLHLYPFGGLRHTVDWSRRFATV
>A0A0B5DEE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces nodosus|TrEMBL
MLQDFSLEMTAKDVPSLEAARGSIPQGTRINVTFLGNEDLEMRLGAARAVKRHGFVPVPH
ISARRLGSRADFERYLSGLQSDGTGENVFTVGGDPAQPEGPYPDSLSLIDSGLLQAYGVR
HVGISGYPEGHPDIAEDVLWSALREKSTSLAAQGVDADVITQFGFDVDPVLAWIERVRGE
GIAHPVRIGVPGPAGVRRLMSYATRFGVGTSATIAKKYGLSLTNLMGTAGPDRFLHALAE
AYDPLRHGQVKIHFYTFGGLGATSEWIVRFRKEALA
>A0A370HUQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga subterranea|TrEMBL
MSPLALRPSRQDSCSIRVSFEFFPPKTPEMEATLWSSIERLAPLSPQFVSVTYGAGGSTR
ERTHATVARLVRETHLKPAAHLTCVAATKPEVDDVVRSYWDAGVRHVVALRGDPVGGLGT
AYAPHPGGYERTCDLVAGIKAIGDFEVSVSAYPEKHPEATSLDADIDVLKEKVDCGADRA
ITQFFFDNDHYFRYLDRVRARGIDIPIVPGIVPVQNFKQTANFAAKTGASIPSWLAARFE
GLDSDVDTRKLIAAAVAAEQVIDLVDRGVSEFHFYTMNRADLVYAICHLLGLRDQSVRAA
A
>A0A3S5GH63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. ESTM1D_MKCIP4_1|TrEMBL
MSAGSRPAARAFIDACSLEVSAKAMPALRAEAGRIARGTTISIPYLASEDDEARLAAARA
VREVGLQPMPHLSARRIGSQAALERFIARAVGEAGVEQCLLIAGDLATPAGPFADSASVI
DTGILERAGIRVVAVGGHPEGHPVMDAAARWRVLEHKCQSIQTRGMTPKIITQFAFDADT
VLAWLDALRARGLGHPVLVGVPGPASVSRLLRYAAMCGVGASTAMLARYGISIGRLLGTA
GPDVFVDRLVAGLTDAHGQVSPHLFPFGGIAPSLDWVAQYRQRADP
>A0A226HF68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium hercynium|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFQPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
VMALRGDAMKDEQYFMPKAGGNDYAIDLVKQISLLNQGKYLHEVMDADNRANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFTFVEKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDQCKNNAQIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASSVF
>A0A329QJ51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytoactinopolyspora halophila|TrEMBL
MSLGLPTTTPENGTTIRELLAAGERSYSFEFFAPKSEQAEELFWRTIRELERLRPTFISV
TYGAGGTSRESTVRVTGQVATDTTLTAMGHLTAVNHSVAELRHVIGSYADAGIRNILALR
GDPPGNPQGEWVPHPEGLNYSEELVRLIKSVGDFCVGVAAFPEKHPRSPDLQTDVDFLVR
KFRAGADFAITQMFFNVEDYLRLRDRVAAAGEDKPIIAGIMPVTNVKQIERFAELSGAEF
PEWLAKRLRAVQDDPEAVRAIGVEVATEMSERLLEEGAPGLHFITLNKSTATREIYQNLG
LGASLVPA
>A0A1V0QTF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Sge12|TrEMBL
MPAAPAATAERPRTSRAPTPAPTPARTPAPPGVRELLAQGRRTFSFEFFPPKTDAGERTL
WAAIRRIEALAPSFVSVTYGAGGSSRSRTVEVTKRIAAETTLRPVAHLTAVGHSTAELRH
IIGQYADAGIRDILALRGDPPGDPKGEWMRHADGLTHAHELVSLIRRLGDFTVGVAAFPE
RHPRSPSWTEDIRHFAAKCHAGADYAITQMFFHAEDYLRLRDRLLAVGCLTPIIPEIMPA
TDFRQIRRFAELSDARFPDALAQRLEAAKDDPAAGHRIGVDYATHMSERLLAEGAPGLHY
ITLNKSTATLEIHQNLNPSHDPATTITE
>A0A1Y1XMR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeromyces robustus|TrEMBL
MKIIKKIEKAIQQKRTFCSFEYFPPKTPQGVNNLYDRFERMALLGPEFIDVTWNAGGVTS
DLTIEICSNAQTVYGLETNMHLTCTNMPVEKIDHALREAKKSGVQNIFALRGDPPRGVKD
WTKCENGFAYAIDLIRYIKKNYGDFFGIGVAGYPEVHPDSPSKEDDLRFLKEKVDAGGDF
IISQYFYDVDLFLQWVKDCRAIGINCPILPGLLPIQTYDKFINMVRMNGTSVPDYILKDL
EPIKEDDQAVKEYGIKLLTEMSKKLIANGIPGIHIYTMNLERSARVILENLGLAQSQEVV
KPLPWNRSLKNNRLKENVRPIFWRNRIKSYIQRTDSWDEFPNGRWGDSRSPAFGEVNLHS
SSSFRYSSEVCLEMWGKPEQTEDVYNVFASYLKGEIKALPWCETALHAESSVIRERLINI
NKKGFLSINSQPSVNGVPSSDKIHGWGPKNGFVFQKAYLELFISPEKLEKLENAIKKDQY
LSYYAINQKGNLKTNQVNESANAVTWGVFPGREIIQPTIVELVSFLAWKDEAFYLWNTWK
SLYESNTKSYDIIDKISNEYYLINIVDNNFQREEKIYDILEEL
>A0A4Z1QTZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MRSETARQNGDIRLSFEFFPPKNPEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPTL
DAVRRMIGDSHLATAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYKP
HPEGYENAAALVKGLREIADFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQF
FFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYDD
DLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A5B8TXM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc mesenteroides|TrEMBL
MTRITDIYKKKSAPVLSFELFPPKTEDGLHALYKTLQEVNPKETGVDYISVTYGAGGGSN
HKKTKEIAEYIERQCGTTALHNLTGINQTPNSLKDTLEKISKVGIENVFALRGDTPTKDY
VNEYYPFAKDLIKEIKNDGRFDIGAAIYPEGHVDNLMTGISVTGVKEKVISGTEFLISQL
FFDNGVFYNMQEALKENYIKVPVSAGILPIISRAQVERITYMTGSSLPARLAKIVHKYEN
QPEALQQAGIEYALEQIHDLLDHGVDGIHLYAMNQPNVLETMLPEINKHIRSKKLTF
>A0A1G1K1D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica bacterium RIFCSPLOWO2_01_FULL_45_10b|TrEMBL
MKIADCYRTKKHTFSFEFFPPKTDEGETKLFQTITQLKSLHPSFVSVTYGAMGTTRDNTI
RIVEKIKNEIGLEAAAHLTCVGHTQDDIEAVLAELHERGVENIVALRGDPPKGETEFKPV
PNGFRYGSELVRFIRKHPKYGKAFSLAVAGYPEGHIECKDKGKDLQHLKQKVDGGADVVI
TQLFFNNRDFFDFVDRCRKIGITIPIVAGIMPVTHGPQIQRFASMCGASIPKVMQEAIQE
FGENQSSVEAFGIEYATKQCRELLDSGIPGIHFYTLN
>A0A3G2DIQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MHDISTSPAIAASIEASPAQVLGPASLAGLFPQGVRVYLTDTGQASQDRLVDAAKHLRDL
GYTPVPHLAARRISSGVEFEEQVKRLAGEAGVSDVLVVGGGVATPAGPFTSSMDMLSTGI
FDRCGINQIAIAGHPEGSPDFSEETATAALKLKYDFAERSDAAMRIVTQFGFDPARFIAW
AEGLAASGIDLPVHIGVSGPARITTLLKYAALCGVGNSIAYLKKNALSLTTLAKGHSPES
VVGPIERHWQANPAGPIRQIHVFPFGGLQNSADWLAGRGSWQIGDADFSAKRGTVAI
>A0A1I5HJS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. Ghvi|TrEMBL
MTDLTKPATADGQNGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLEPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTPYSAHPDGYQTSDALVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDA
GATRAITQVFFDNDFYFRYLDRVRTRGINIPIVPGIMPMHNFKQARNFVTRNGTSVPDWL
AAKFEGLDNDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A1F0HZH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. HMSC073E02|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEIAKIIY
>A0A1B3NSW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. RAC06|TrEMBL
MTMPERPIAKTPDARISFEFFPPKSPDMEDQLWQAVKALQPYQPDFVSVTYGAGGTTREP
TLATVKRLIAETPLATASHLTCVGATRDEVRAVVEEFQAAGVRHFVALRGDPQGGVGSRY
APHPGGFVNAADLVSGLRDLGDFEISVSAYPERHPESENDDVDLDMLKQKVDAGATRALT
QFFFDNDIFERYLERVRAAGITIPIVPGIMPIQNLTQLKRFASMCGASTPSFLDERFEGT
EGDAQARAAVAADIAAEQIADLARRGIEEFHIYTMNRAPLTIATLDRLGITAKAAKVSSA
AA
>A0A117KYL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium 42_11|TrEMBL
MSRLRELLESGRFVITAEVGPPKGSDVNDFREKVNLLKGRIDAFNVTDGQGASMRLSSLA
GCLVVLSEGEEPVMQITGRDRNRIAIQSELLGAYALGVRNVLAITGDYPTLGDNPNAKPV
YDLDSVGILLAASSLMNGKDLAGNPLKGNPPKFYLGATANPNFSPLELELIKVEKKVSAG
ARFFQTQAVYDLRVAEQFIKRVAKFNVKILLGIIPLRSVKSAQFISRMIPGVKISKELMH
RMEVAEDPKLEGLKIAADFIKKVREHGLAHGVHIMAIGAEKTVPVLLEML
>A0A2M8DKG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium CG_4_9_14_0_8_um_filter_70_14|TrEMBL
MGTQLYEHGLFLNQCYDAANLTHPQLVQEIHEQYAEAGAEILETNTFGASRQKLTPYGFG
DQVEAINRAGAAIARKVAGKTLFVAGAVGPLPLRLAPLGKVSAASACAAFTEQMRGLVAG
GIDLFCLESFGLITEILAALEAAREVAPGLPVIAQMTVDENGYTSHGTPAEEFARALDQA
GAEVIGVNCSVGPAPMLETIERIAAVTGRPLSAQPNAGLPRNVDDRLIYMSSPEYFAEYA
RNFVRAGVKIVGGCCGTGPAHIRAMRSAIRSLVPGRTTIHIEPREQLAGAATPPPLAARS
ALGAKLAAGRFVTSVEITPPRGADASGVLESCRTLKGAGIDIVNIPDGPRASARMGAQHL
AILIERAVGIESCLHYTCRDRNLLAMQSDLLGLAALGIHNILIITGDPPKMGDYPDATAV
FDIDSVGLTHLAAATNHGLDLGGNRIGPPTSFVIGVGANPGATNLDRELDHFRAKVEQGA
EFAITQPVFDPQILLRFLDKIEPFRIPILAGIWPLVSLRNAEFMAHEVPGVIVPDVLVER
MRVASARSKEAARDAGLAIAREALAAVKDRIDGVQVSAPFGRVELALPVIEAAADRL
>A0A7J9W0N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MPGRADQSGAALLPRLLADGIVVSDGAVGTMLHAAGVPLDRSLSELNTTAPALVRDLHAA
YVAAGARIIQTNTFEANRLRLARFGLGDSVAESNIAAARLAREAVAHARDSSDDQPPVFV
AGSIGPATSSSAAPPIPLRARLDAVAEQVGALAGWVDLLVLETFGDVESLLRAVDIAAAE
SDLPVIAQLTFGDDGRTLRGETPFEAAHLLGDRDVLALGANCTVGPAVLRDVVAELAAGT
DRPVSVQPNAGLPQRLGKQFRYAHNTRYFAQAAADFVAAGANVVGGCCGTTPAHVRAIAK
AVSSLRPARPPAPVAEPPRRGRIVVTAARPAEPPSEPAVAVAWPQPDRFHVIAGLQTPGD
QEVADFVSRAQRLRTAGADLIALREPAPPRTRVNPIAAGLLLRERVGSDVVLPVETADRS
LAALQADLLGAHALGLQIVVCRTGAPRVAGDYPDPAVLWDVDSIGLIRTLRGLNEGTDWR
GVAMAERTRFSVGASLTTMAADIDYELDRAEAKVRAGAEFLLTDVVYDAEEARTVLQALV
ERGIDRPVLAAIAPFDDARTLERLSFEMPHLTAPSSALAALRCRNESSDDDTAAAAAVTA
AVETIDALADLVAGVVLHVPADRSDHGADLIARVTARGAQP
>T0IBM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. UNSWDHB|TrEMBL
MKISEIFKVKKVLSFEIFPPKPTAAVNTIYDTVDQLRELMPDFISVTYGAGGGKNNTETL
EIASVVKNTYGIESVAHLPCINLSKTDVQKILDDCKNAGIENVLALRGDAGSATKNGFQH
ASDLVSFIKANGDFHIIGACYPEGHKECASVVEDIYNLKTKVDAGADQLITQLFFDNQYF
YSFRERAVNAGINVPIEAGIMPVVNKKQIERIVTLCGVNLPKKFLSIMDRYENNPEAMRD
AGIAYAIDQIVDLIAQGVDGIHLYTMNSPYIAHRIYEAINTLLVA
>A0A5E5QP26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Gammaproteobacteria bacterium|TrEMBL
MKTSFEFFPPRTAKGKQTLHQVRQELSSLNPEYFSVTFGALGTTQEVTLETVLDIQKNDT
VAAAPHLSCIGSKKEIIIELLDQYKAANINRLVALRGDIPSGVRDIGDFHYANELVEFVK
SQYNHHFHIEIAAYPEMHPESKNRLTDLQHFADKVKAGADGAITQYFYDADAYFKFVDAT
EKLGINIPITPGIMPITNYTQLVRFSKMCGAKIPHWILKKLELYQDDFDSLSAFGLEVVT
NLCQTLKAQGVNNFHFYSMNRSQPSLEIAKHL
>A0A2A9E6C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sanguibacter antarcticus|TrEMBL
MTRLPLVQADPRSACPKDMMFGPCGGVGADGACEVSPVRCTFVDDPVALWPGDVPVAAGG
VLHAPSPAAVELAELVRARPVVISGLPARALDADSIRQCAEILHGTVDAVLAGDSGRARV
QLPPAYRAHVIQEAGLRAWMGLSCRDRNRVALEGEVAALADVGVAGVHCVTGDHTLTGTR
PDARPVFDMESTELVALARRWGLATSVAESPAAPPVDLRPARLAQKVAAGGELCFLQYCG
DVDDVRRFIDRSREAGVTIGFVPGVPVVIDRAGAELLESFAAAVLPPGYVEGILAAPDAY
QAGVAAAIDLSEQLLAIDGVVGVLPAGGPEPGTEVAFAHALASIGRALGAGEPLAPRTR
>A0A1T5LAV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plantibacter cousiniae|TrEMBL
MTTTEPACPRRTPFSFELYPPKTLDGGLALARTVEHLAAAGPEFISVTFGAGGSSRTASL
DVLRSIRTSTSVDPMAHLTCVGSTHAQASRLIKDFLDAGVHSFLALRGDPPAGAVEGDAF
LGDLGSAAELVQLIGRVSAEHEPYAEGSLVGLPGAVQLGRRHRPRIAVAAFPNGHPRSRS
TTQDLDTLLAKQAAGATLAITQLFFHADDYLAFAERARRHGVTMPILPGVMPITSPARLR
RVLELSGEALPSDLAIALEVEPDEAGRIDIGTDYSARLIRDIVAGGAPGVHLYAFNQHRT
VLDVLHRAGIPVQGGRPVRHPIPDPLTSKDAR
>A0A3E4QYU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella tanakaei|TrEMBL
MRVDQIFEQAKAAGAQPVSFEMFPPKGEMTLERAREVAGSFSQLNPDFISVTYSAGGSGN
NGATTKIAQMIDADFGIPSVAHLTCISLKRADLLAKIDEMRAAGIQNVLALRGDVPQGAP
TGPGCADYRYAKEIIPHLVDAGFCVGAAAYPEGHIECDDLELSVRQLKEKQDAGASFLVT
QLFFDNQYFYRFRELAERTGITVPITAGIMPFMGKQQISRMVFMCGASLPSPVIKLLARY
EDDADSLRAAGIEYACRQLEDLAANGVDGLHVYTMNRADVAGAAMSALRA
>A0A370XA75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella psychrodurans|TrEMBL
MPAISFEFFPPKTDEQRAQLDRTAKDLKGLKPEYVSVTFGAGGSTLSYTGDTVAHLHQQH
GLDVAPHLSCMGGTRAEIAGLLDSYRAAGYRRIVALRGDLPSGMATPGDFRYAAELVRFI
REHSGDHFHIEVAAYPEMHPQAEDVHADLRHFKAKVDAGADGAITQYFFNADAYFRFVDD
ARRLGVTVPIVPGIMPISQYAQLKRFSDACGAEIPRWMSKRMQAYYDDVESIRAMGAEVV
AQLCRRLLEGGAPGLHFYTLNRAKATRAVLDQLG
>A0A1G9T4S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Siphonobacter aquaeclarae|TrEMBL
MKVTEHIREANGKTLFSLEIIPPLKGQHIGELIGAIEPLMEFKPPFIDVTYHREELIEKR
HPNGLIEKVPVRRRPGTVGICARLMERFKVDAVPHVICGGFTKDETEDFLYDLHYLGIDN
VLILRGDPEKSAGVFRSKEGGHRYASELVAQVADMNRGRLLHEETEASPTNFCMGVAGYP
EKHFEAPNLGNDLKYLKEKVDLGAEYIVTQMFFDNQKYFDFVNRCREAGINVPIIPGLKP
LSTKKQLSVLPRIFHLDMPEELVKAVEACATDKDVKQVGIEWAIQQCKELQQFGAPVLHF
YTMARSENVQTIARAIF
>A0A1M2VJ27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trametes pubescens|TrEMBL
METCMHLTCTGMPKEKVDIALREAKQHGCRNVLALRGDPPVGKEWEAVEGGFRYGVDLVH
HIRKEYGDYFDIAVAGYPQTQRLPPDEREREMGYLKAKIDAGANFIFTQMFYDVDMFIEW
VQAARAAGITVPIVPGIMPVQTWNGFQKATFLAKITVPQAFLDELEPHKNNDEKVREIGT
RLVADLCRRILAADIGIKGLHFYTMNLEKGCRLLLEELNLVPRVEVIKPLPWRQSLTPNR
RTENIRPIFWANRTRSYLSRTENWDEYPNGRFGDSRSPAYGELDGYGIWIKQTTEDALRL
WDTPTSVEEIRKLFSRFCVGDLAALPWSDSTPSSETSVIAQQLAKLNELGFLTINSQPAV
DGAKSSDRIHGWGPANGYVYQKAYLEFFVSPELLDMLIPHIERDINITYYVINNRGDLRT
NTHSDGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGRQWAKLYEPESPTSKLID
SIMDTYCLVNVVHNDYKKPDAIFQPFFKAGAEYAAKYGSASPPATNGTNGHAN
>A0A7V6Q6U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterales bacterium|TrEMBL
MSSNFKNKLKSGQFTVTVEISSPKGTYLNRILQDISELKDMADAVNICDNPMAHVRMGSI
QLAHIIQEKAGMEAIPHMTCRDRNIIGIQSELLGAWALGIKNIFAVTGDTPDKGDHPGAA
GVFEVDSKGLIRIIDTLNNGRDLANNTLEGSTDFFIGTAANPAAEDLGREIEKMKEKIDC
GANFIQTQPVYDMDVLDRFLEKALLLDVPILVGIMPLKSQRMAINFNSRVEGVNIPLKII
DRMKRGRREGVEISRELAEGIRERGCGIHLMPLGDVEAAVQIIKGIGLSVEKVNDASGIS
>A0A829H592|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei subsp. paracasei Lpp41|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPHACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFPGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A829RNS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 1130196|TrEMBL
MKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGKARDIQDFEQFLEQA
QAANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGVRIGGGFNPFKYVE
AERDAQYLKLHKKIKAGADFIITQLGYDIEALKKAKSFLTKNNYSQQILACVMPLTLGRA
NFMVKHKVAGIVITPHMLKVLAEEKQAGHTDSVYLRCALQILICKHLGFAGIHLSACHKP
EEQMLLESYVEQYRHLELNVLEELWNSLWQVTTGKEFSPEIARFSRQPTSKQLIKYRQLH
VMHEAMFGSKIAKGVGRFIFKASFWENALVAKVLLKTEVLSKHSLVGCESCGQCRLGDTL
YICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVEQTEILKEKLIPTVAIE
TRGTSSWKNWYLGAEA
>A0A508BSE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MHDNEPTGPTAAAGSRGEALSSAETGTARRLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPAGGVTGGGRQGSAHEPEAGRCEAPRVRAVQEQTNPSECVLAHV
LDSSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRAEDVAGELRHA
DDLVRVIREVEADFFGDGRRHVTIAVAAYPATNDHIEAIEVLAAKQAAGADMAITQVFYD
AADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSSLGSASGATL
VERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDAV
DRGYLQATPGRGPSFLRCGSARATVSSHHPVQPLTTITKENA
>A0A6J3LWA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dissoconium aciculare CBS 342.82|TrEMBL
MHITKKLAASHAKGQATYSFEYFPPKTAQGVQNLYDRMDMMHSWGPSFIDITWGAGGRHS
QLTCEMVKTAQSVYGLETCMHLTCTDMERSKVDDALKECYNAGCTNILALRGDPPREQEK
WEAAEGGFRVAADLIKYIKEKYGDHFDIGVAGYPEGPDENTSADEHIVYLKEKIDAGGTF
IVTQACYDADIFIDWAKKVRAAGISESVPIIPGIMPISTYAAFVRRAKWTNSHVPPEWYA
QLDPVKEDDSIVREIGRDLMTGFCQRLLDFGIKHLHFYTMNLAGGSRMILEKLNMVPAED
VPHPDIKPLPWRQSLGLNRREENVRPIFWRNRSRAYIARTQDWDEFPNGRWGDSRSPAFG
SLDEYGIGLKGTNEQNRKLWGEPKNIKEVSDLFVGYMSGKVSSLPWSESPINTEANALVK
DLVDINKRGLFTINSQPPVDGAKSSDPVYGWGPRNGYVYQKAYLEVLVHPSLIKTLIERM
DKDPEITYFAVNNRGELITNTQDDSGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYY
LGSEWSKCYDESSESRRLIKEISETWYLVNIVHNDFRKARPIFDLFDGLQAPGIEEQQSS
KLTNGHHEVNGEKSLPELNGVPDGNNVVNGANHVAAAAH
>A0A7J0CLD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces microflavus|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRIEAVRPSFVSVTYGAGGSTRAGTVRA
TQQIAADSTLTPVAHLTAVSHSVAELRNMIGQYADAGIRNILAVRGDPPGDPLAEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLERFSQLSNATVPEPLKERILAVKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A7V6MWS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterales bacterium|TrEMBL
MGLKDKIESGGFAITAEMAPPKGIDFNHIRECARAVKGRVDAVNVTDFQSAVVRTSSLGG
AKILLEEGLEPVMQITGRDRNRIAVQGELLSAAALGIKNVLALTGDHPSIGDHPEAKGVF
DMDSVNILQTATKLASGEDLTGHELSGIPEYFLGASVTPLYDPVELQIMKMKKKTRAGAK
FFQTQAVYDIDVIKSFMDKIKDMDVKVLVGVIPLKSAGMARYMNNNVPGIRVPDEIIDRM
KKA
>W6TWU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. V48|TrEMBL
MKIVDHINNAKDKTLFSFELLPPVKGKSIDEIYKAIDPLMEFNPPFIDVTYHREDYIYKQ
HSNGLLEKVSYRKRPGTVAICAAIMNRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADSSFIPTPGGHAFATDLLQQVTDMNSGKYLHEDHSAFKTDFCIGVAGYP
EKHFEAPNLKTDFKYLKQKVDMGAEFIVTQMFFDNTKYVNFVQQCRENGINVPIIPGLKP
ITSSKQLISLPKVFHIDLPEELTEAVQACKDEKQVKEVGIEWMIHQCKELIQVGAPVLHF
YTMSNPEPTKKIAQAIF
>A0A374I030|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. TF10-5|TrEMBL
MKISDACNHKKSLSFEIFPPKKDSELKNIDATLDVLCELQPDFISVTFGAGGSLNCNRTI
ELAKKIKQNYHVEPVVHLTCLHYNRAEIDEFARILTAEGIQNVLALRGDRNPDLTEKDDF
KHASDLISYLKPKGDFCFLGACYPECHPESANKIEEIRHLKEKVNAGAEVLLSQLFFDNT
QFYRFVEDCRIADINVPIVPGIMPVINAAQIKRMITMCGASFPERFQKIIHRFEDNKAAL
FDAGMSYALSQIIDLLANDTDGIHLYTMNNPVVARKICEGIQHII
>A0A3C0FTY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira sp|TrEMBL
AGLKEIADFDISVSAYPETHPDAPSSDFEIDYLKRKIDAGANRAITQFFFDNETYLRFRD
KCVAAGIE
>A0A1H9QQ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Giesbergeria anulus|TrEMBL
MTAATASATGLPVSLEFFPPKTPEGASKLQAVRQQLYALRPEFCSVTYGAGGSTHEGTFA
TVRDILAEGMDAASHFSCIGATRDTVREQLATLKAMGVRRLVALRGDLPSGYGLGGEFNY
ASDLVAFIRAETGQDFQIEVAAYPEVHPQAKSPEADLQAFATKVRAGADSAITQYFYNAD
AYFRFVEDARKLGADVPVVPGIMPIASSTQLLRFSDACGAEIPRWIRLRLQAYGDDTASI
KAFGLDVVTQLCEQLRQGGAPALHFYTMNQNTATLEICKRLGLAG
>A0A2W2K2U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NTH33|TrEMBL
MALGTASTRTDRARTVRDILAAGKPTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPAGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADYAITQMFFQPESYLRLRDRVTAAGCETPVIPEVMPVTSVRMLERLPQLSNAVI
PDALKERILAAKDDPAAVRSMGIEFATEFCARLQAEGVPGLHFITLNNSTATLEIYENLG
LHRPPQT
>A0A3D9DX77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kushneria indalinina DSM 14324|TrEMBL
MSDPRSPDISFEFFPPRTDAGRDRLPEVYTRLAELNPRFFSVTFGAGGTTRDFTFDAVKS
MSRDTGICTAPHLSCVASDKDDLRRLLRQYREHGIKRIVALRGDMPSGMLGVGEFRYARN
LVDFIREETGDHFDLTVAAYPECHPQASSFERDIDHFADKVRAGADMAITQYFFNPDAYH
HFVDRVRARGVDVPIIPGIMPITNYTKLARFSEMCGAEIPRWVRRQLEAYGDDSESIRAF
GHDVVTRLCQQLLDQGAPGLHFYTLNQAETCTNIVTDLSLDKIGH
>A0A1E4XG84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. AP19|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTKYQQAGIQRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1R1M8Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Motiliproteus sp. MSK22-1|TrEMBL
MDDAYSSMLSDFSLETTAQGAEHFQMLSDVPEGTQVKVAFLGNETFDQRLSAIEVLCASR
VCPMPIISARRLESAWVLDSYLTQAKQVGQIESIFLVGGDPSTPQGVFADSLDVINSNIL
DRFDIKTVGIAGYPEGHPRIHTEVLWACLKRKVDELSSRGFSVEITTQLSFDAERVIFWV
EQIRSEGIHVPIRIGIPSPSTVKGLLKFAGQCRVGTSLRLLRQYGWQVTSLLGNVGPADF
LEAFREGVQDRDLGDVRLHVFPMGDLSTVMLWMKGVATQPCE
>C3QEW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. D1|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAADINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A3D3H7X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MAHATPTTESAKRLVEGYSLEITGKEKDVVGLTEAASLIPAGTKVNVTFLGNEDLPMRVA
AAKAVKELGFVPVPHISARRIASQAQLEEFLSALAEIGATEHVFAVGGDPATPEGPYPDA
LTMIRSGVLQQYGVKEVSIAGYPEGHPDIATDVLWQHLEDKSAALKDAGLDAVILTQFSF
DTDPVMAWIKGVRDRGIDTQIRLGTPGPAGIKRLISFASRFGVGANAMIVKKYGFSLTNL
MGSAGPDKFVSDLAALFDADPSVGAVKLHMYTFGGLEATATWARDFIAK
>A0A1Q8VFI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MRDNEPTEPTEPTAAAGSRGDALSSTETGSARRLPTVSLELFPPRPGKAASATWGRIDRL
LATGPDFVSVTYRPTFVTDPAGGDSGDEYEGNRCGIAPRVRAVQEQTNPSECVLAHVLES
STIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRADDVAGELRHADDL
VRVIREVETDFFGDSRRHVTIAVAAYPATSDHIEAIEVLATKQAAGADMAITQVFYDAAD
YVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSTLGSASGATLVER
GIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDAVDRG
YLQATPGRGPSFLRCGSPGAALSSRHPVQPHTTITKENA
>C5M548|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida tropicalis (strain ATCC MYA-3404 / T1)|TrEMBL
MSTVSERISSLKPDERFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFITITWGAGGSTS
EKSLDLAATCQKEVGITTVLHLTCTNTNKEIIDEALARAKANGIRNILALRGDPPRAEEY
WTPNCDFNGAVDLVRYIRQQYGDYFCIGVAAYPEGHVDGADISGQDPKKDIPFLIEKVKA
GGDFIVTQLFYDVDKFIAFEKLIQEHDELKNIPLIPGLMPITTYKVFNRAAKLSHATIPR
EISQQVDKVSHDDDAVKALGVEILSNIIDRIDKETNIKGYHFYTLNLEKAVASILDKSDV
LRPILEGPSTVMEHDDAIASDSDDDEDMNTGQAVSVTRRRSSINDNSLMGSKALIGKALL
KDKKTLVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHSPAEAEIKW
GSPETTKDLAQIFIDYLSGKIDVIPWADQALSPETALIQEELFQLNEKGWFSVASQPAAN
ACKSTDNIFGWGPRNGVVYQKAFVELFMPKDDWNKLKPLVEASDSITYYAADKTNKIEAK
VPAGHDIKLTKNAVTWGVFPSKEVLQPTVIDYESFKAWNEESFLLWLEWSRCYKKNSKSF
ELLNKVYENYVLVCLIYHDFPEEHGLWDFLLDE
>A0A1H5XF45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera chlorobenzoica|TrEMBL
MYSVRLWSVRNARALHRLYAFFSRLAPRLAPLVRRIGVQHVETVLRPLEQGAKNVFFDCR
MCGQCVLSSTGMACPMNCAKQMRNGPCGGVRADGHCEVEPGMRCVWVEATEGTKRIAADH
LAHPTPLLPAIDQRRRGRSTWLEVVHGRPAPVFQPPVGERITPEGEQSQFERSCASGRPV
VTVEIAPPDSADPAALLARAELFRGLVDAMNITDGAGGNCHMSSVAASAILATHGFEPVY
QIACRDRNRIAIQGDLLGAAALGVKNILCLTGDDVSRGDHPQAKPVFDLDAVSLLHVARG
MCDRGEFASGRKLEQAPDLFIGATVNPFVPPYVDRVANLEKKIRAGARFIQTQFCFDVER
FADFMTEVRRRGLHRQAHILVGVGTLGSAKALRWMANNVPGVCIPEALLARIEAAPDQKA
EAKQVCIEIIRAVTAIEGVAGVHLMGHRNEAVLARIIVDAGLRAPPPTMDEADPAAAPAT
SRRAAA
>A0A4P9JDG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citricoccus sp. SGAir0253|TrEMBL
MNTTPATGRQTVMTEPSLEMTGKDKDIESLREAAPAIPQGTRINVTFLGNEDLSMRVKAS
TAARDLGFVPVPHISARRLTSRAELEEFLTALREQVGATHAFSVGGDPSEPMGPYASSLD
VIQTGLFKDHGFTDVSIAGYPEGHPDISEGQLWDALERKNASLKEQGLNGTILTQFGFDV
DPIVHWIEEVRRRGVDLPIRVGVPGPAGIKRLLTYASRFGVSTSAGIAKKYGFSLTNLLG
TAGPDKLITALDQAMTPAHGDVKLHFYTFGGMRATAEWIAEYQRKH
>A0A7G9L1T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sabuli|TrEMBL
MNRHPLSDDRAHLDPLFAKARGDIEVSFEFFPPKTEKMAATLWDSVQTLEPLHPRFVSVT
YGAGGSTRERTHATVKRILEETDLTPAAHLTCVGASRDEIDAVARDYWDIGVRHIVALRG
DPSEPGARFEPHPDGYANAAELVAGLKRIAPFDISVACYPEIHPDSGTKSADLDNLKRKV
DAGADRTISQFFFSADAFLRFRDEAADAGIDVEIVPGILPVSNVATTRRFAQTCGACIPD
WLNHMFEGLDDLPAARQLIAATVAAELCGQLYAEGVRTFHFYTLNRAELSYAICHLLGVR
PQ
>A0NMJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium aggregatum (strain ATCC 25650 / DSM 13394 / JCM 20685 / NBRC 16684 / NCIMB 2208 / IAM 12614 / B1)|TrEMBL
MTDQRLLANGRLPASTEMSPKQVVEKTELLEFIPAGTQVYVTDLGNCSEDMIIDAARTLR
DNRLTAVPHMAARRYASREDFERRITRLTQEAGVTEVLAIAGEAEKAGPLTSSVALLETG
LFDQLGIQKIAVAGHPEGAPDIKPEVIKSFLQRKHELARQSDAEFRIVTQFGFDPHRVSL
WLDELREWGNEFPVHVGVAGPAKMTTLLKYAAFAGVENSFNFLKKRGGAVVSMLSGYDPD
TMVDPLETRVTSQPDTQLAQIHAYPFGGIQKTAEWLLSRGSWSFQTSSSILTANESA
>A0A4Q5TLW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MTDGPAPTSSRSLLEDLRHPRPCVSFEFFPPKDDAGEEVLWRTIADLEPLQPTFVSVTYG
AGGTSQERTVRVTSRIAEQSRIRAIGHLTLVGQSRAEIEQVLKQYASAGIHHVLALRGDP
KGGPREPWEPHPGGMDHAIELVELARELGDFSIGVAAFPEGHPDAGGRDPDADVLVAKHR
AGAEFAITQFFFRVQDYVDLVERTRARGSDLPIVPGIMPILNFGQVARMAELSGAEIPRE
VLDVIEPVADDKDAVRTRGIELATQLCRDLLAAGAPGLHFITLNRSKATREIFETLRGEG
LV
>A0A7Y2TV50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boseongicola sp|TrEMBL
MSQPTISFEFFPPQSLEASFRLWDTVSTLAHLDPAFVSVTYGAGGTTRKLTHEAVETLGT
HMGLDVAAHLTCVDASREETLEIAESYAKSGVKRIVALRGDPPKGAQSFSAHPDGFTDAP
ELVAALAETGQFEITVGAYPDRHPEAAHANADIDWLKRKIDAGATNAITQFFFEAETFLR
FRDACTKAGITAEIIPGILPIENWSGTRRFAKRCGARIPPTFSAMFETAERDGRSDLLST
AICTELCTDLLEEGANHLHFYTLNKPGLTRDVVHALGLAPDTTLEKVA
>T0YLW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MNHAQYERVFSFEFFPPKTAEGAEKLRHTRRQLAQLNPAFFSVTYGAGGTTQDRTLETVV
EIQQDGYPAAPHLSCIGATRDSLRQVLALYRHHGIRHLVALRGDLPSGTLGGGEFRYASD
LVRFVREETGDHFFIEVAAYPEVHPQAHSAQEGIRHFQEKVEAGADSAITQYFYNPDAYF
SFVEDCGAAGITVPIVPGIMPIANFSQLSRFSDACGA
>A0A7X7K637|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MSPATERPTVSFELFPPRDVDSAPRLWDTIRHLEAARPDFVSVTYGASGSTRETTRALVT
RILRETSLNPIAHLTCVATSRKEIACVVEEFLDAGVRSFLALRGDPPTAGAGWEAHPDGL
RTAAELVTLLRQIESRRCAQSPSQQVRATVRPLSIAVAAFPRGNHGAGSTREQDIQALLD
KQSAGADFAVTQLFYDAESYLELVGEARRSGVRIPIIPGIIPATDPARLLRTQELTGVPV
PRDLLARLEAADDDAARRRLGVRATADLVKAVLDGGAPGIHLYTFNRHEAALGVLDAVGL
LPGSARPTSQPDPAPAYTI
>K0D1Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas macleodii (strain Black Sea 11)|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGA
>A0A1H9CHB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium RM5|TrEMBL
MKVSEIQKAKKRTLSFEIFPPKKDSELKNIDETLSILCDLNPDFISVTFGAGGSINSNNT
IEVAKKIKYKYNVEPVVHLTCLHYDKDEIDSFAKVLREEGIENILALRGDRNNNIAEKNV
FKYSTDLVNYLENKYDFCVLGACYPEVHPESGSKVNDVIHLKEKVDAGVEMLLSQLFFDN
EIFYRFRDNCRIAGINVPVIPGIMPVINASQIKRMVSLCHASFPEKFKKIVERYESNKRA
LFDAGMSYALSQIIDLLVSDTSGIHLYTMNNPVVARRICDGIKNIV
>A0A4Y8CZ03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryotinia calthae|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHHIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAAL
EEVKNDDAAVRNIGKDLVAEMCRRIIEAGVHHLHFYTMNLAQATRMVLEELSLTPSNQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLESGIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHEP
DLTYYAVKKTGDVQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLNEPFETSESGD
VDGVRFTEPQTVPLTNGEANGH
>A0A166RBJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. EI5c|TrEMBL
MTAVGNAARMTSRTVAECLESGRTSFSFEFFPPKTAEGERQLWTALREVEALQPTFVSVT
YGAGGSTRDGTIRVTERIATDTTLTPIGHLTAVNHSVAELRQVIGSYAGAGVRNVLALRG
DPPGDPQADWVRHPEGLGHAEDLVRLVRSLGDFCVGVAAFPDKHPRSPDLETDARFLVRK
LDAGADFAITQFFFGADDYFRLVERVRRLGCDAPIIPGVMPVTNVAQIERMAQLSGADFP
ADLAVRLRAVADDPAAVRAIGIEVATELSERLLAGGAPGIHFITLNRSAATREIYKALTD
>T1BSY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
QALRLQVSFEFFPPANPQLERSLWRALERLAPLGPDFVSVTYGALGSTRMRTHDIVTGIH
RQTSLRPAAHLTCVGASRSDIDTILRRYWDAGIRHIVALRGDAPEGQGAFTPHPQGYGFA
AELVAGIRSFADFEISVAAHPEGHPETPGIQAEIENLKRKEDAGAVRAITQYFFDPAIYL
RFRDRARRAGVRMPIIPGILPVTDFTQLGRISARCGARVPVWLTHLFEGLDNDPETGKLV
GAQVTAELCQSLRREGVEALHFYTLNRPELTRAICRFLGIVESRPPATHPAAPSLRV
>A0A4U8TN95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter japonicus|TrEMBL
MFGFEFLPQDREEDITTLRAMRNGAQNYLKQKVDFVLIPANVRKNAGVNAILSAYMLSLH
FKDMFFVPTISAAGLDKIQILSQILSLKYANFTCVALIGGDDTNKVRNEKIDGIELIQMT
RDALGSDISIISGTPTDINNPTTRERLVQKLYLGVDRIITQPIFCPNQAKEFIRSFTELK
RQSKSSAKLSLGVFGIFSLQSVRAINEAHLGFEVPKSYIEQMQGEAGQEDSNTSLVAFKH
LWENLQKIGQENDVYLYLSTPKHNDLRAYGVQVSEK
>A0A1J5SGR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MGNTTTPISFEFYPPQTPEGVEKLAVVRQRLAVVKPEFFSVTFGAGGSTQDRTLKTIRQI
HAEGHNATPHLSCVGSTRDNVRALLFAYKDMGIRRIVALRGDLPSGMASIGEFQYANELV
SFIRAQTGEHFHIEVAAYPEFHPQANSAREDMLNFKRKVNAGANSAITQYFYNADGYFRF
VDECRKLGVTAPIVPGIMPIMRFSQLARFSDACGAEIPRWMRKTMEGYGDDVESVQAFGL
DVVTQLCEKLIAGGAPGLHFYTLNQAGASLEILKRLGYR
>A0A1J5T9L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MGINTKTPISFEFYPPQTPEGVGKLTAVRQRLAAVGPEFFSVTFGAGGSTQDRTLETIRH
IHAEGRSAAPHLSCVGSTRDNVRALLFAYKDMGIKRIVALRGDLPSGMASIGEFQYANEL
VSFIRAQTGEHFHIEVAAYPEFHPQAHSPREDMLNFKRKINAGANSAITQYFYNADAYFR
FVDETRKLGVTAPIVPGIMPIMRFSQLARFSDNCGAEIPRWMRKTMEGYGDDVESVQSFG
LDVVTQLCEKLIANGVPGLHFYTLNHADASLEILKRLGYQ
>A0A0P9PB34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. cerasicola|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1Y2MM78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia autotrophica|TrEMBL
MSGGLRAALAAGRFALTAELGPPRGADTEDFLHRARLLSGWVDAVNITDNQGARVRMSSL
GGAVIAGRAGLSPVMQLTCRDRNRMALQSDLLAAGALGVPQVLLLTGDHPRFGDHPESRP
VFDVDAVQAIGIARAMRDDGVLLSGEPLSANPGWLIGAVENPFAPPAGFRARRLAKKVAA
GAEFVQTQYVFDVEPLRRWMAELVDLGVPPRCAVLPGVGPIRSLRMLEFLRTGVPGISVP
PAVEKRLRGVLPGRVAEEGIRLCVETLQQLPDIPGVSGAHVMAFGFERGVPEILDRAGLG
PVPCEPDRPVVVSGR
>A0A1W1HL09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfamplus magnetovallimortis|TrEMBL
MSELKSGSNLEKVLKAGHFAFTGECGPPKGANVEHLVGKFKHLKGNVDAVNMTDNQTAVV
RMSSLAASHIMIHEGLEPNFQMVCRDRNRLAITADILGAHALGIRNMLCLSGDHQSFGNH
PQAKNVHDIDSMQLINLVTTMRDKEEFINGEKIDVAPKLFVGAACNPFADPFEYRVYRLA
NKIAAGADFIQTQCIYNMEKFRTFMKQVVDMGLHEKCYILAGVTPMKNARMANFMSKFVP
GMDVPDSLIDRLKGAEKGKQAEEGIKFALEQIEEFKEMEGIAGVHLMAIEWEHMVPEIAE
RAGVLPRPVV
>A0A258TEX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. 28-66-16|TrEMBL
MMISVSQLEEARRALEAPLFADLAGDSVVSFEFFPPKTEKMEEALWEAIKTLEPLGPRFV
SVTYGAGGSTRERTHASVARIQRETSMAAAAHLTCVDASRDEIDAVADAYWQAGVRHIVA
LRGDPPVAGARFVPHPAGYENAAALVAGLRKLHPFEISVAAYPELHPDSADAVADIDNLK
RKMDAGANRAITQFFFSPEAYFRFRDRAAAAGIGAEIVPGILPVSNVAQTRKFAGMCGAE
IPAWMDRLFEGLDDHPPARQLVAATLAAEMCRKLYAGGVRHFHFYTLNRAELSFAICHLL
GLRAKPAAAPAVAAA
>A0A4U8TSB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter japonicus|TrEMBL
MNIEFMIEKLRSCKSFLSLEVSPSVSAQLDKQLVEQLQDIQKVDAFVCTDSPLARFKPSS
ILNSIKLQQALKKPVICTLSMRDRNSIALCGDILAANEFGLRTFLTLTGDSIKNGDCLEA
KGVFEDSSLKLGMIIDNLNEGKAVNGKILKEKVDTIYNFQVINAYANNPQSIINKMQKKL
NASHISALFTQPVYSAKAAEFLLTNIETLNAQNKSNCALVLGFFPVMSYKTALFLRDKLP
GVFIPNEWVQKLEKAHHKGIDEENKVGLENSLVLMQEIQKVHNKFHFMSANKPNLVKEFI
>A0A1Y3MUY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piromyces sp. (strain E2)|TrEMBL
MKIIKKIEKAIQQKRTFCSFEYFPPKTPQGVNNLYDRFERMALLGPEFIDVTWNAGGVTS
DLTIEICSNAQTVYGLETNMHLTCTNMPVEKIDHALREAKKAGVQNIFALRGDPPRGVKD
WTKCENGFAFAIDLIRYIKKNYGDFFGIGVAGYPEVHPDSPSKEDDLKFLKEKVDAGADF
IISQYFYDVDLFIQWVKDCRAVGINCPILPGLLPIQTYDKFINMIRMNNTSVPEYILNDL
EPIKEDDQAVKEYGIKLLTEMSKKLIANGIPGIHIYTMNLERSARVILENLGLAQSQEIV
KPLPWNRSLKNNRLKENVRPIFWRNRIKSYIQRTDSWDEFPNGRWGDSRSPAYGEVNLHS
SSSFKYASSDCLNMWGNPEKPEDIFGVFAKYLKGEIKALPWCETALHAESSVIRERLINI
NKKGFLSINSQPSVNGVPSTDKVHGWGPKNGFVFQKAYLEFFISPEKLQKLEEAIKEDEY
LSYYAINQKGDLKTNQKDESPNAVTWGVFPGREILQPTIVEKVSFLAWKDEAFTLWNVWK
DLYENNSKSYEIVDKVSRDYYLINIVDNNFQRVDKIYDILEKL
>R6AID7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides stercoris CAG:120|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEKNGYHHAVELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTNEILKCKTDAEAQQVGIEWCVQQCKELMKHHIPSIHF
YSIGAVDSIKEVAKQIY
>A0A2T0VZU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yoonia maritima|TrEMBL
MIVVKVMNLLQLIKAEITAWQERGPSMSTPSVSFEFFPPKSLEGSFRLWDCVNVLAPLDP
TFVSVTYGAGGTTRKLTHEAVGAIHRTSGLNVAAHLTCVDATKAETLEIADGYAQEGVRE
IVALRGDAPKGSDGFKPHAEGFASSVELIGALADTGKFNIRVGAYPEKHPEAADQAADIA
FLKRKIDAGATSAITQFFFEADTFFRFRDACVKAGIDAPILPGILPIENWAGTQRFARMC
GTTIPQVVTDAFQHATRDGTTDLLATALATELCDDLLQGGVDHLHFYTLNRPELTRDVCH
ALGVTPKGRLQNVA
>A0A484HM38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacteraceae bacterium|TrEMBL
MRLKRKFDSGEFAVLAEIQPPKGVDVSAMVSGAMRVKGEVTAFMTPEMTNAEMRMSSLGA
AVILQQKGMETVMQANCRDRNRLALQADLLAAGACEIPNIMAVKGEETTFGDHHQARPAH
DIDTLDLIRAAAGLSAGADMSGVELMGAPDFLIGASADPGVGGKSAEMGIADMKEKIEAG
ARFFVTPPIFDPALIESFAKKIDMKDIRVTPTVLLLKSLGMARYIARNVAGIDIPDATID
RIRKSRDKTRECVEIAAETAREIRKQGFAGVLISTMGWEDKLPDILKKI
>A0A7I0DI91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Sr3|TrEMBL
MPHTSDPACRKIPFSFELYPPTSDAATSVLHATIERLAAAGPEFISVTYGANGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSNAESSQLIREFLDAGVRSFLALRGDPPEGIREGEAF
LGDLGSAAELVQLIHRVQAERVPYREAVIPGLPAARTIKREREKVRIAVAAFPNGHPRSR
SATQDIDALLAKQAAGANLAITQLFFHADHYLSFILRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRQATELARQLIAGGAPGLHLYAFNQHE
TVLAVLDGCGLLTPTLPASALPAPHPVKENS
>A0A7H8NXH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. NA06056|TrEMBL
MVPADRAQRAQAFISAFSLEVSAKAMSALRAEASRVAPGTTISIPYLPSEDDTARLAAVR
TARELGFEPMPHLSARRIGSREALERFIDRAVIDAGVERCLLIAGDLSTPAGPFADSTSI
IESGVLQRAGIKVVGVGGHPQGHPVMAGADRWRVLERKCQRIEEQGMAPLIITQFAFDAD
IVLTWLNELRVRGIPHPVLVGIPGPASIARLVRYAAMCGVAASTSMLSRYGISIGRLLGT
AGPDVFVNRLVDGLTEAHGLVSPHVFAFGGIAQWMDWAEHYCRGVET
>A0A417A7B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM45-5|TrEMBL
MNLREYLKETNLITDGAFGTYFAAKYQTQEIPELANLSDPEKVKKIHEEYLNAGANFIRT
NTFAANTETLQESFPEVEKNIRAAVEIARSAAEGKNVWIAGDIGPIPVNGTEDAAAAADE
YYEIAKTFAETGVKVLDFETFADLDGILPAIKKIRAEYDMFIAVSFSVNQFGYSAAGLSA
KRLLADAAAVPGIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPVYFAEKMKELQELGADILGGCCGTDPEFIREMFAWDGILKKGAPEKEAESSGQSEH
VVRQGFLYDENGNRKEKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMANKVRQATGLNVMPHICCRDRNAIAMRSLFLGAAINDIYNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTEGDAVRLRRIKDETGARILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKASRKEGEAVGIQLAKEVMKLVEDFADGYYFSFPFNRVYMLKDICNCSVGLRTCCAN
RNKTQA
>A0A2K9I5R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus pentosus|TrEMBL
MNLRQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHQSYIQAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVRIAVTAREHADHPVYILGTIGGLAGDTDAAVQR
ATQTEIAANVTEQLTALLATEQLDGILLETYYDLNELLAALKIVKAHTDLPVITNVSMLA
AGVLRNGTSFTDAIVQLHAAGADVIGTNCRLGPYYLAQSFENLAIPADVKLAVYPNSGLP
GTDQDGAIVYDGEPSYFEEYAERFRQLGLSIIGGCCGTTPLHTAATVRGLSSRSLVPHNA
PTHVAQAPTLVTTKSQHRFLHKVATEKTVLVELDPPRDFDTRKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTAIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAV
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TDVSTKSISRKLSYGCDYIITQPVYDLANVDALADALAANQIDVPVFVGVMPLVSRRNAE
FLHHEVHGIRLPKSVLERMQQAELDGNERAVGITIAKELIDGICARFNGVHIVTPFNRFK
TVLELVNYVQQKNLTKVQ
>A0A6N2HA88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AR8-1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDVSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A419R5V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tsuneonella suprasediminis|TrEMBL
MNTPAPQEPAFAALPGDIGVSFEFFPPKSEKMETQLWNAIKELAPLNPRFVSVTYGAGGS
TRERTHATVARLVTETPLTPAAHLTCVGASKREIDEIVDAYWDAGVRHIVALRGDPPPDS
GGRFIPHPDGYASAADLVEGLRKRHDFEISVAAYPEVHPEADSAQADLDNLKRKIDAGAS
QAITQFFYSTDAYFRFLDKALAAGIDVPILPGIMPVTTFAAIRRMSANTAIPGWMESLFD
GLDERPGPRALVAATVAADFCRRLYDGGVRDFHFYTLNRADQAFAVCQLLGLRATGDSQ
>A0A7G8W5T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. PAMC28562|TrEMBL
MGLPLSFEFFPPKTVEGATKLRAIRQQLYTRKPEFCSVTYGAGGSTHDGTFNTVREILGE
GVDAASHFSCIGSTKATVRMQLAELKAMGVKRLVALRGDLPSGYGVGGEFLYASDLVSFI
REETGRDFHIEVACYPEVHPQSRSPEADLRAYAAKVEAGADSAITQYFFSAEAYFRFVDE
ARKLKLDVPVVPGVMPITNSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCVRLRDGGAPALHFYTMNQAAATLGVLERIE
>A0A6N3GH09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium paraputrificum|TrEMBL
MNIKELFENKKVVFSFEIFPPKTTSSIETIYKTLESLKGLSPDYMSITFGAGGSVQDNRT
IELSSLVKNKYGIEAVAHLTCISSTKNEIEYYLEKLKENNIKNILGLRGDVPTDGKIIGE
FNHANELIDFINKKGNFNIAAACYPEGHIEHKGLYREIESMKRKEEAGASYFISQLFFDN
NLFYNFKDEVRAANINLPIEAGIMPVTNKKQIERMVALSGASLPDKFRRIMERYEHNPEA
LRDAGIAYAVEQIVDLVSTGVEGIHLYVMNNPYVAEKISGSVGRIIESVNKVELV
>A0A7K3WAV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter deserti|TrEMBL
MAQTVRELLVPGVPSWSFEFFPPKNAESEAQLWTALRELERLRPSFVSMTYGAGGSTREG
TVSVTERIAAETTMLPLAHLTAVDHSIAELRHVVSRLAAAGVRNLLALRGDPPGSDPQAD
WVAHPDGLHYAAELVELIKGIGDFCVGVAAFPELHPRSVDADTDVDMFVAKCRAGADFAI
TQMFFRVEDYLRLRDRVAARGCDVPVIAGVMPVTNARSISRIVQLSGQAFPQDLADRFAA
ADGDRPEDKAAVRALGVEVATTMCERLLDEGVPGIHFITMNRSTATREVYTNLTSRVPLA
TA
>U4V1S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium HIMB11|TrEMBL
MTRPQISFEFFPPQNFEGAYRLWDTVNTLAPLDPRFMSVTYGAGGTTRTLTQEATRVLHK
HTGCDVAAHLTCVDATRDETLNIARSYADTGVTGLVALRGDPPAESGAFHSHEDGFQNTV
ELVGALADLDAFHLFVGAYPQTHPEAADAAQNIGWLKQKLDAGADEALTQFFFEAEDFLR
FRDACAKAGITKPITPGILPIENWQGVKRFAKRCGATLPAWLEDAYAKAERDERTDLLSI
ALCTELCSELVDEGVEALHFYTLNRPELTRDVCAAMGIHPKVTLRHVA
>A0A0J7YWV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces viridochromogenes|TrEMBL
MGAARLRALLDGVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLAARLAAH
GYRVVPHVPARLLRDDAHLKEAVDRLREAGVDDVFVPAGDADPPAGGYDGALPVLRRLSE
LGGPFAHIGVTGYPESHPLIDDDVTVQAMWDKREHATYIVSNLCFDPRVLGEWIGRIRRR
EVDLPVYVGVAGPVQRAKLLAMATKVGVGESTRFLTKHPSWFLRFAAPGGYSPDGLLARA
EGALTAPAAGVAGLHLFTFNQIAETEKWRRALLDRLGG
>A0A2P6S8K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rosa chinensis|TrEMBL
MYFCPNICTGKSISTSPNWLEQDGLDQLPETRKIKNELLEELNRKGFIIINSQAAVNGER
FDSASFGGYVYQKAYVEFFCSKETLDVLIEKCKVHLSLTYMAVNRQGSCWISNLDQSNIN
AVTWGVFPRKEIIERTVDAARFRVWKDEAFEIWSEKLLEQGNNYFLVSLVDNDYIHGDLS
TVFPDF
>A0A023WMJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MTTSRPSISFEFFPTKTDAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDTKAELRELLNIYKDAGIKRIVALRGDLPSGMGMASGELRYANE
LVEFIRSETGDHFHIEIAAYPEMHPQARSFEDDLANFVRKARAGADSAITQYFFNADCYF
YFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQAF
GEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A0L1MG24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARHLATFNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A7GVY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter curvus (strain 525.92)|TrEMBL
MLIQKIKNNEAGILLYGLTPPKENLTDEETATIAAKQIARLEGQNIDGIVLYDLQDESSR
TNEERPFEFIKTTPPETYYETYLKKHFKAVIYKAVGKYDEPEFCEFLRHQQEDFICVFVG
ASSKSQEVKLRLDEAYALKAKFAPNITLGGICIPERHASKLDEHLKVAHKSEKGCEFFIT
QAVYNLENAKKFIDDYAKLEGKKCPIIFTFTPCGSAKTLLFMKWLGINIPPNFEERLNAS
ENILQTSLNLCLEIFNFLYKYGLAKGISVGANVESVSNRKVEIEASITLLKQIQEIIAKT
NTAYHWIGAGV
>A9EC90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter indolifex HEL-45|TrEMBL
MTTPAVSFEVFPPRTVGAAFKLWDAAQALAPLAPRFFSVTYGAGGTTRDLTHDSAHVLHR
TSGLPVAGHLTCVGASRAETMDVAEKFAEAGIKDIVALRGDPQAGTDKFAPHPEGFADSC
ELIEALAKTGKFTIRVGAYPDPHPEAADQQANIDWLKRKFDAGADEALTQFFFEADTFLR
FRDACVKAGIDKPITPGILPVVNWTSARKFAVKCGTPIPEWVDQAYEAAIRDDRHDLLAQ
ALCTELCSDLIDEGVDALHFYTLNRAELTRDVCRAIGVTPQVDLSDVA
>Q0HZD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. (strain MR-7)|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETNLVAAPHLTLVDASDEELLDLAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAADLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPSWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPKAV
>W8RF82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MSHTRSRNFSFEFFPTKTDAGHEKLMATARRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKQELRELIGLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRNETGDHFHIEIAAYPEMHPQARNFESDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVETPIIPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDIESIQT
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWDNLKLVR
>A0A2G6YAM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. 62|TrEMBL
MNAAKTEATGFPVSLEFFPPKTPEGAEKLRAVRQQLYALHPEFCSVTYGAGGSTQEGTFT
TVREILAEGVSAASHFSCIGATRQSVREQLAVLKGMGVRRLVALRGDLPSGYGAGGEFQY
ASDLVTFIREETGRDFHIEVAAYPEVHPQARSPEADLKAYVAKVQAGADAAITQYFYNSD
AYFRFLEDTQKLGANIPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLEL
>A0A1E5HG22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus ureilyticus|TrEMBL
MRTDTLFKEKTVFSYEIFPPRRTAPVDTIYHTLDRLKGQQPDFISVTLGAGGTGANLSTA
DIAQKIQDEQFLPSVAHLPAVNFSKDEIKVILEELKQKKVENILALRGDILPDKEPKKDF
SYANDLVAFIQEQGDFNIIGACYPETHSDAANSVEDIRNLKRKVDSGVNQLISQLFFDNN
YFYTFKEKCDIAAIEVPIQAGIMPVVNKRQIERMIKMSNVTLPTKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVSQGTEGIHLYTMNNPYVAQKIREATRSLFET
>A0A3M6K7F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilus sp|TrEMBL
MTIRYEANPPKILPDVDTDESIKKFIERIKDVSKKCDAIHLTENVLGFQRVSPIEVGKII
RKEIPDLPITVSLRVRDKSEEEISEFVDNCIDIGFAGILVLMGDPSQTGKADSGQIPSLT
VKKLREKNVDSKIDLYLSVSNKPNFSKLEKKKDAKPKGFMTQVVQNAQQVQALEDNLKGF
SIIPIILFPSQKNEKSAKFLDLDLESYSQEFEELLKKAHEITGDVLLTSPNDFTGLNEFL
GKTSF
>A0A6N7Y9M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Conexibacter sp. W3-3-2|TrEMBL
MRIDELLARNGDPTFSFEFFPPKTEAGEENLYAALRELQPLEPAYVSVTYGAGGSTREKT
IEIVSTIKEKFGLEAMAHFTCVNATTDDLRGALDQLRDAGVENVLALRGDPPAGETRWTK
TDGGLEYSRELVELLAAEYPEFAIAGAAFPETHIDAVSPEADLEYLKQKVDAGATFLVTQ
LFFENRFYFDFVERARAAGITVPIIAGIMPITNVEGIKRMTTLSGCALPAGLEQALDARR
ENPEAVAELGVSYATLQCADLLAGGCPGIHFYTLNRSPATRAILSALKLWRPWERATGLA
VPPEKATA
>A0A7C5HTB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MHLKRKFDTEGFAVLAEMEPPKGVDISGMITHAMRVKGKVDAFVVPEMSNAVMRMSALGG
AMILQAKGMDTVMQVNCRDRNRIALQADLLAAYGCGITNVMAVTGEDPSFGDHFKARSVY
DIDLLELLRTIRGLEQGKDMAGIELSGSPEFLVGSTVDAGAKGKSTELEIEEMNKKIEAG
AQFFISPPLFDLSAIQPFMKRVEQNKIKIIPTVLLLKSLGMARYIMRNVEDVYIPDTLID
RIHKSSDKVRECTLIASEMVASLKKEGFSGVNIATIGWEHKLPEILDNVHP
>A0A6A6QBG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lophium mytilinum|TrEMBL
MHISQMLEQSRRKNKSTFSFEFFPPKTAQGVQNLYDRMDRMHSFGPTFIDITWGAGGRMA
HLTSEMVKVAQSVYGLETCMHLTCTDMEKSKIDEALKDAYKAGCTNILALRGDPPREKEK
WEATAGGFRYAKDLVKYIRDTYGNHFDIGVAGYSEGCEDQDDHELLLEHLKEKVDAGATF
IVTQMFYDVDIFLDWVDKVRARGVTIPIIPGIMPIHTHAAFMRRATWTKCNIPTAWTKAL
EPIKNDDAQVREVGKTLIAEMCRRLLEAGILHLHFYTMNLAQTTRMVLEELDLMPDMSSP
IDKPLPWRPSLGLNRREENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDARSPAFGELDA
YGVGLKGTNEQNIKLWGSPTSVKDIANLFVRYMSGKLDSLPWSEAPISKEAESLQTDLIN
LNTRGFLTINSQPAVDGIKSSDPVLGWGPHNGYVYQKAYLEVFVSPEYIAEVITRIERDP
DMTYYAVNKAGDLKTNAPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFFRLGQDW
ANCYSSVSPSRYVVEDLMDTWYLVNIVHNDFHVPHGIFPLFDGLEVEDMAKPLHSTRVVN
GDEKSSINGAAAHTNGVNGQELKN
>A0A7D7V5I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilus sp|TrEMBL
MTIRYEANPPKILPDVDTNKSIQKFVEKIKIISKKCDAIHITENVLGFQRVSPVEVGKII
KKEIPNIPITVSLRVRDKTKQEISEFVDNCISIGFSGILILMGDKSKTGKIDSGQIPSST
VKRLRGQGADSKIDLYLSISNKPNFSKVRKKVDANPKGFMTQVIQDISQVQDLSENLKGF
SIIPILLYPSPKNEKSAKFLGLDLESYGQRFEEMLKRTHEITGDVLLTSPSDFSGLDKFL
EKSNI
>A0A7C1C4Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLERVLASGAFAVTGELGPPKNSDPDIVRQKARILKGNVDAVNITDCQTAIVRMS
SIGAGLIAQSEGVEPVIQMTCRDRNRIGMQSDLLAASAMGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQMLGMVRDMRDGKKFQCGEEIKGPEPRFLLGAAANPFAHPFEFRAVRLGKK
VANGADFIQTQIIYNVDKFTRFMEMVRDLGLHEKCSILAGVTPPKSLGMARYMKKFVPGM
DVTDEVIERMKGAEDKQQEGINICVDIINQVKEIKGVAGVHVMAIGWEDAVAEIVESAGL
LPRPTFDEEKEVQEPVAAPETIVVRGDADNMLAEAKAEAEKIIAAARKEAELITSRAAAE
PAPVETAGPTEAVAVATDDAGEHEMNEKMRLMALESVEQGLNALKKAYGLNDDQFDALLK
FVETETILKREFATAKKTPAAPAAPAAPVTPAAPVTPAAPVAPAAEDSAEKAAAVEAEAK
AEAEAKAEAEAKAEAEAKAAREAEAAEQAKIAAAAKAKEEAAAKAREEAEAAAKAKAEAK
AEVKEEAAPKAEPAKTAPAAGLAVPDLAVEKTRFSERSTKVPESTYHQAYSGSIREVVLG
NDDQSVTVGGAKVLPFHLFEGDMPRKPLIAMEILDIKPDNWPPTLLQYFEDVVGNPVDWA
QKCVNEYQADALNVSLIGTDPNGLNRSSTDAARDAADVIMAVEVPIIVWGCGNIDKDTET
LRELTSLIGDKKVCLAPLQDGNYRPLGATAMAFQHPMVAASPIDVNLAKQLNILLENLGV
SLDSVLMDPSIGALGYGIEYSYSVMERIRIAALTQQDDKLQVPIICNLGREVWKTKEVGL
PSDDLLGDQERRGIMMEAMTASCMLLAGGDVLIMRHPKAINMTKSLINGLMA
>A0A3M6K9D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilus sp|TrEMBL
MTIRYEANPPKILPDVDTDQSIKKFIDRIKDISKKCDAIHLTENVLGFQRVSPIEVGKII
RKEIPDLPITVSLRVRDKSEEEISEFVENCIDIGFAGILVLMGDPSQTGKADSGQIPSLT
VKKLREKNVDSKIDLYLSVSNKPNFSKLGKKTDAKPKGFMTQVVQKVEQVQALADNLKEF
SIIPIILFPSQKNEKSAKFLDLDLELYSQEFEELLKKAHEITGDVLLTSPNDFTGLNEFL
GKTSF
>A0A6M3NUE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Worthington|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A525D0U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSEFKSGSNLEKILKAGHFAFTGECGPPKGANVAHLKEKFQYLKGNVDAVNMTDNQTAVV
RMSSLAGSALLFQEGLEPNFQMVCRDRNRLAMMADILGAYALGVRNMLCLSGDHQTFGNH
PQAKNVHCIDSMQLIAMVKKMRDEEKFLNEEDIDVAPKMFVGAACNPFADPYEYRVHRLA
SKIDAGADFIQTQCIFNMEKFRDFMKMTVDMGLHEKCYILAGVTPMKNAGMANFMKKFVP
GMDIPDELIKRLKSVDKKEQAEEGIKFALEQIEEFKEMEGVAGVHLMAIEWEQRVPEIAE
RANVLPRPQVD
>A0A2T7L306|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CS131|TrEMBL
MALGTASTRTDHARTVREMLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLERFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A2A3CNH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3864|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIQEFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A484D6U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perca flavescens|TrEMBL
MGTGGPLFIDITWHPAGDPGSDKETSSLMIASTAVNYCGLESILHLTCCNQTKEKISGHL
AKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKHIRSEFDDYFDICVAGYPTGHP
EAESYEEDLRHLKEKVDAGADFIITQLFFRADTFLKFLDDCRAIGITCPILPGIFPIQGY
QSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIKQAVEMCRVLLDSGKVPGLHFYT
LNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWD
EFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGDELMSEESVYEVFTCYITAQ
PNRSGHKVMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIAGWGP
AGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWG
IFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLV
DNDFPLESCLWQVIDDMFELLDAAPEPLDAVSEPLNAAPEPLDAVSEPLNDGAASK
>A0A484D6U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morone flavescens|TrEMBL
MGTGGPLFIDITWHPAGDPGSDKETSSLMIASTAVNYCGLESILHLTCCNQTKEKISGHL
AKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKHIRSEFDDYFDICVAGYPTGHP
EAESYEEDLRHLKEKVDAGADFIITQLFFRADTFLKFLDDCRAIGITCPILPGIFPIQGY
QSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIKQAVEMCRVLLDSGKVPGLHFYT
LNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWD
EFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGDELMSEESVYEVFTCYITAQ
PNRSGHKVMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIAGWGP
AGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWG
IFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLV
DNDFPLESCLWQVIDDMFELLDAAPEPLDAVSEPLNAAPEPLDAVSEPLNDGAASK
>A0A5Q2MKK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium yanjiei|TrEMBL
MRNRSTARELRRLLESSRYEVLPTASIEDKILASVPRGHTMTITASPGKGLGATLDLAER
LAGHGYVAVPHLAARMISGRDELAEIVARLQAAGIDSVFVPAGDADAVGDYSGSLDLLHD
LTAMGSPFRHVGVTGYPESHPTIADDVTVQAMWDKRHHATTLVSNLCFDPQLVRTWVQRV
RSRGAVMPLLIGMPGPVERTKLLSMATKIGVSESTRFLAKNKSVFARIAMPGGFSPEKFL
ERIAPTTQEPASHVEGLHLFTFNQVAETEAWRQELLGRLATAAIA
>A0A0D8KFE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium nepotum 39/7|TrEMBL
MLRSETARREGDIRLSFEFFPPKNPEMETHLWETVAELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLATAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIGTDYR
PHPQGYENAAALVKGLREIGDFEVSVSAYPEKHPESASDAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMDRVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFAGYD
DDLEGRARVAAEVAAEQIADLQRRGINEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>F2BFS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria bacilliformis ATCC BAA-1200|TrEMBL
MRHILILYRPSEKRGGFAQAVCKIPKQIKRHKSRSCTGGVFFITRCTFSDYYQTFENQTG
RLKKYGAQEHAMNTANKTLSFEFFPTRTPEGRDKQTAVREKLRRFNPAFFSCTSGAGGST
REGTLQTIADILAENTPAAPHLPCIGMNEAEIHTLLDTYRDMGVRRIVALRGDMPSGMGA
SGSGLRYAAELVELIRHRYGDLFRIEIAAYPEYHPQARSAAEDTAHFAAKARAGADSAIT
QYFYNADAYFRFVDDVRTLGCTIPVVPGIMPVTGFAKLMRFSDTCGAEIPRWLRLKLQSY
ADDTESVQAFALDVVTDMCARLLEQGAPGLHFYTMNQSALPEEICRRLGFGA
>A0A413AYB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF13-37|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A3N5U567|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MNCKTPSKLEKILAAGHFAVTSECGPPRGSSIDHIVHKANLIKDHVDAINITDNQTSVTR
LCSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAASFDIYNMLCLSGDHQSFGDCA
QGQNVHDLDSMQLLQTVRHMRDEGKFLGGADIDRPPKMFVGAAANPFADPFEIRVPRLAK
KIAAGAEFIQTQCIYNLDKFELWMKMVRERGLHEKVHILAGLTPLKTAGMAKYMKNRVPG
MDVPDDVVKRMAGTPKEKQAEEGIKICIESIQRLKEVEGVKGFHIMAIEWEEKVPEIVEK
TGLYPRPEVG
>J3CML3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. YR522|TrEMBL
MKPHNFSIEFFPPKTAEGTEKLRVTRAKLNALQPKYFSVTFGAGGSTQQGTRDTVLEIIG
EGFEAAPHLSCIGSSRQSLRAILQDYKANGVSRLVALRGDLPSGYGAMDQASSEFRYANE
LVEFVRAETGDWFNIEVAAYPEMHPQAKSPQDDLQNFVRKVKAGADSAITQYFYNADAYF
RFVDDAARLGVQVPVVAGIMPITNYSQLMRFSDMCGTEIPRWVRLKLASYGDDVESIRAF
GLDVVTQLGERLLQGGAPGLHFYSLNQAGPTQAIWSRLLKS
>A0A0Q7VMF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. Root1480D1|TrEMBL
MANHNFSIEFFPPKTPEGAEKLRGVRAKLSELHPKYFSVTFGAGGSTQQGTLDTVLEIME
AGEEAAPHLSCIGGTRESIRAILQQYKSHGIKRLVALRGDLPSGYGMSGEFRYANELVEF
VRAETGDWFHIEVAAYPEVHPQARSPQDDMQAFVRKVNAGANAAITQYFYNADAYFHFVD
AAQKAGVNVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VSDLCERLLAGGAPGLHFYSMNQAVATTALWNRLVSPQ
>A0A3D6C893|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSECRTESRLEKVMRAGHLGVTSECGPPRGSDPAEVREKGALIKDHVDAVNVTDNQTAMT
RMSSLAACVHLKLEGIEPVLQMVTRDRNRVALQSDILGAASFDINNMLCLSGDHQSFGDC
AQGQNVHDLDSMQLVQTARHMRDEGKFLGGADIKRPPKMFVGAAANPFADPFEIRIPRLA
KKIACGAEFIQTQCIYNIDKFKEWMKRAVDRGLTEKAFIMAGMTPMKSVGMAKYMKNKVP
GMDVPEEIIKRLAGVDKKAQAQEGIDICVEHIQQLKEVEGVAGFHIMAIEWEEKVPEIVE
RSGLYPRPEV
>A0A525D0L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MNLKEALEKKRFVVTSEVQAPMGDDDPETLIDRLKKVKGRVDGVSVSEIELEGVVGDTIK
TCEILKQNRFNAIYQTTTRDKNRYQLQKDLSTAHDSGVENLLVFTEDYRISGDTLQESMF
FHVDSGKLGSVLDHLKQGVTIEGQELGKKMDFVLGSGVETPWGKNVPKRGMEEMEDMMNV
GTGYFLTTPIFDLDQFSRFMKQVGQFNVPVIAEVMILRTAGMGKFLNRHFKSGLVPDWVI
QKLQQSPDKQKASIELFAETVNGLRDICQGVHIITIGGEDKLGKYLNAAKLR
>A0A523HS07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldithrix sp|TrEMBL
MKVIEHFEKANKPLISFEIIPPKRGGDMSSLLSIIDDLAQFNPPFIDITSHAAEVIYEET
PTGFQKKIKRKRPGTLGICALIQNKYNIDAVPHILCRGFTREETEDLLIELQYLGIDNVL
AIRGDDSGYEKPILYGRSANPYALELVQQITDMNRGKYLEDNLLDAEPSNFCIGVAGYPE
KHFESPNLRMDIQCMKAKADAGADYVVTQMFFDNSAYFKFLEVSREEGLKVPIIPGLKIL
TTKGNLSAVPRKFYVNIPEELAKEVAAAKPEHVMEIGVNWAAKQVEELLNKGAPSLHFYI
MQNSKPIMMLMKKIKL
>A0A1E7X5Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella phyllosphaerae|TrEMBL
MAHHNFSIEFFPPKTVEGAEKLRATRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILA
AGEDAAPHLSCVGGTRASIREILNEFKSHNIRRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGDWFHIEVAAYPEVHPQAKSPQDDLLAFERKIKAGANAAITQYFYNADAYFQFVE
QTRKLGIDVPIVPGIMPILNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTQLGQRLLAGGAPGLHFYSMNQAAATTALWQRLV
>A0A8D5LYT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax sp. MIZ03|TrEMBL
MSPDRFPVSIEFFPPKTPEGVEKLRLVRQQLYALKPEFCSVTFGAGGSTQEGTFNTVRDI
LSEGMSAASHFSCIGATRERVREQLATLKAMGVKRLVALRGDLPSGYGTGGEFQYASDLV
AFIRAEMPDDFHIEVAAYPETHPQAKSPESDLKAFAAKVQAGANSAITQYFYNSDAYFRF
VEEADALGVQIPVVPGIMPIASSSQLMRFSDACGAEIPRWIRLRLQAFGDDTASIKAFGL
DVVTDLCEQLRAGGAPGLHFYSMNQSAATLEICRRLGV
>A0A7U4DQQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / VKM B-1956 / 1pr3)|TrEMBL
MQIPQLIKERRPFVSLEFFPPKKQEEWPAFLEVAQELKQLHPLFASVTYGAGGSTQSNTL
EICERLITSCGFEVMPHLTGVTANPEKIDGFLEAIKALGIDNVLALRGDRPTGFTGSDAE
LFAAFPHASDLVTYIRSHHPRLAIGVAGFTEGHAEAPSFAADLEVMQRKVECGADFVITQ
LYFDNRTYFDYVERLRVRGVNVPIVPGILPIRNLGSLRFVLEMCNARIPGRLINALIKAH
DEGGAEAVYEIGVAYAREQVKGLLAGGAPGVHLYTLNKADMCLQVMDGLL
>A0A838DGS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MDLLEELQTRIVCGDGAMGTMLIEGGVPLERCFEELCVSAPERVSAIHEQYIAAGARVIE
TNTFGANAVRMERCGFDSRVGEINRAAAQLARQAARSKDVVVAGSVGPLGISADEAAARG
IDRAQCFREQITGLLDGGAEWIFFETFMDHEELALALAVKNEIGAAPVVCSFACAPEGRL
SSGIPVVEAFGKLRDAGAKILGVNCMNGPHGMVQLLERLPADDLLAAYANAGYPKYHEGR
FIYHTAPDYFGQSAREMVAQGARLIGGCCGTGPAHIKAIAEAIAGLQPVRSKTVRMTVEP
LAARTATPAGATEESLLERMANGHRVIICELDPPKTLALEKFFTGAQALVKAGCDAITLA
DNSLAILRVSNLAMAAMLKERFGITPLLHLSCRDRNVLGLQSELLGMAALGMRHVLPLTG
DPARVGDHPGAASVYDVNSVELISIIKRLNEGFSHAGKAIKSTTGFVIGCTFNPNARNLD
SQVNRLERKVAAGAQYAMTQPVFDLGLIEETKCRTAHLNIPIFMGVWPLLSGRQAEFLHN
EVPGIVVPDSVRAEMAGAEGADGRARGVKLAKVITEGALAHFNGVYLITPFLQYETTVEL
AQFARSL
>A0A7V6PEJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella intermedia|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDVKPAAHLTCVDATREEVDRVVREFAALGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKVETAL
EMA
>A0A412HLG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF23-6|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAHEVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A5K7Z7R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina widdelii|TrEMBL
MSNNGYKSGSNLEKVLKAGHFAFTGECGPPKGANVEHLKEKFEHLRGKVDAVNVTDNQTA
VVRMSSAAASAIMVANDIEPNFQMVCRDRNRLAMMADVLGVYSLGVRNMLCLSGDHQKFG
NHPQSKNVYDIDSMQLIAMVKKMRDEGKFLNEEEIDVPPKMFIGAAANPFADPYEFRIYR
LANKIDAGADFIQTQCIYNMPRFRDFMKKAVDMGLTEKAYILAGVTPMKSARMAQYMAKM
VPGMDVPEELIERLKGAGKGKQAEEGIKFAIEQIEEFKEMEGVAGVHLMAIEWEHKVPEI
AERANVLPRPQVD
>A4NZ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae 22.4-21|TrEMBL
METLLWDSIHRLKVLKPKFVSVTYGANSGERDRTHGIVKAIKQETGLEAAPHLTGIDATP
EELTQIARDYWDSGIRRIVALRGDEPNGYAKKPFYASDLVELLRSVADFDISVAAYPEVH
PEAKSAQADLINLKRKIDAGANHVITQFFFDIENYLRFRDRCASIGIDTEIVPGILPVTN
FKQLQKMASFTNVKIPAWLVKAYDGLDDDPTTRNLVAASVAMDMVKILSREGVNDFHFYT
LNRSELTYAICHMLGVRP
>A0A1J4ZAX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG1_02_43_210|TrEMBL
MIKKITDIFKEKPRTYSFEFFSPKTDAGIARLYDTVGELVKLGPDFLSVTYGAGGSTRET
TTKIVDQLQKRFDVSVLHHLTCIGHTKDELTGIISNIKQAGVKNILALRGDPPVGVKEWK
KIPGGFEYSYQLVDMIRSLHKDYFSIGAAGFPECHMNCSSYELDTKYLKLKIDSGADFAL
TQLFFDNNDYFKYIDRLKKAGIKNRVIPGILPIVNYEKLVNFCSTCGASIPDKVRAIFEP
IKDNEKATHKTGVEFAVKQCQGLLDSGAPGLHFYTLNRIDPVREIIKNIKL
>A0A1Q6IRS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odoribacter sp. 43_10|TrEMBL
MTKVIDIINQKKAPFASFELVPPLKGSDINKLYGAIEPLMEFAPPFINITFHRDEVEFRQ
TADGTFEKVTITKRPGSVAIAAAIMKRFPVEVVPHLICGGASKHQIENDLIDLNFLDIQN
VVALRGDAIPGQKYFVPEPDGHRYSCELVEQIHNMNRGIYLDECLKNAVPTNFCIGVAAY
PEKHYEAPNIDIDIENLKRKVDAGADYIVTQMFFDNTRFYEFAAKCRAAGITVPIIPGLK
PISTQTHIEMLPRAFSIDLPQELMNEVRKCKDNKAIYQVGIEWCTAQSKDLLVHGAPAIH
YYTMGKADNIREILKRTF
>A0A3Q3FJY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labrus bergylta|TrEMBL
MVNHVQRVDGSWQACKSDSSGASNSGGESSKESSRCSTPVLDADRSDRLRDKMRRRIESG
DCWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTREKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAI
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGADFVITQLFFRVDTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPQEITKVIEPIKDNDAAIRN
YGIQQAVEMCRVLLDSGKVPGLHFYTLNREVAPMEVLRQLGLWIEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLQMWGEELMSEESVFEVFTSYITAQPNRGGQKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLNVLKKYEPRV
NYHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVADPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPEPPSDGAVS
E
>A0A191TMJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachidicoccus sp. BS20|TrEMBL
MKITEHIQQAKDTLISFEILPPLKGKDISSIYNHLNPLMEFKPSWINVTYHRADTMIKKR
NDGTFEKVAVRKRPGTVGICAAIMNHYQVDAAPHIICGGFTKSDTEDALIDLNFLGIRNV
LVLRGDAAKNETHFEPEIGGHRYAIDLLKQVKNLNRGIYLDDEIIEGGKTDFCAGVAGYP
ETHFEAKSYEEDLQRLKEKADAGADYIMTQMFFDNKKFFKFVEDCKSLGINIPIIPGLKP
LINKKQLSVLPKIFNVEIPHDLSNAILQTTNDADAEKIGIEWLVQQCKELKAFGVPVLHF
YTLGKPQTIYNVVKEIV
>A0A5V6Q0X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Cardoner|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2D7QUI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MSDFLHQIERRILVGDGGLGTQLRLRLPSNIPCLDACNIDPIFRNFVYEIHADYGRAGAD
IIQTNTYGANQLKLDLQGYGNQLESINLAGVQLASQAATEISSSQNRQVFVAGSVGPLET
NPLEDELSITEVRQAFTAQMEVLVSAGVDLLILETFTDLRQTKIATKLAVKFGLPVMVQI
SGISKGVVSDGTDVRVFAQTLSQLGASVIGLNCRGPHDLLLAAEKIARVTDIPLSVQPNA
GTPRIDQGKISTTYSVSPDHFSGFIKKFLSLGINVIGGCCGTTSEYISVIRENTDGYVPA
RRQTQIFVFPDNQKLSKSKISPNPIKQIFETNDRIVSVEMRANTFPQLRAMIKVSKNLAD
LEVDLFDVPDNAGATVNIGAIGTAFKLQQVSNIPTLIHWTTRQRNLISIQSHLLEAWALG
IKGVIALSGDHPKVGRFETAKIVTDVRGSVQLMELLKRLNQGTLIDGTSLGEPCDFYVGG
GFTITKNLKPQLKHLRRKVERGAKFIYTQPVYDLSTAEDVCQSIKNEGLDTKILLGILPI
TSLRSISFLQDNLGMYIPSIVVKQFQDIDNPKDQLLYGLSIARDLVSRLSEQNRFSVDGI
YIIPPSRMNWANKQVAITQLVQSFRKRKTEER
>A0A2V4F3P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SMT-1|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQVARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQASPKPMLACLMSLTHGRATMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALETRIEYWQTQVQSLEQWAPA
WHASWQMPGLPAVTFHPPQAGWRLDESRVDASFKEKARYHLMHGMHALLFSRRNSLSKAF
GWAVRQPLWGTRVGAHVLHTLERSVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A7G7Z4U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. SH5A2|TrEMBL
MSRHEHPLGISFEFFPPGTDAGRDKLIQTRDELATRKPRFFSVTYGAGGSTQARTREVVR
KVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVDFIRDETGDHFNIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
HFVEKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIADF
GTDVVSRLCQRLLDGGAPGLHFYTLNQSKPVLKIVDNLSG
>F9HNQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis SK1080|TrEMBL
MTMSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLA
DFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYA
TDLIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERF
YDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLR
AAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>N0DZ80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycicoccus elongatus Lp2|TrEMBL
MVPHIPYRLRAERPSISFEFFPPKDDGSEAQLWEAIRHLERIRPDFVSVTYGAGGTTQDR
TIRVTERIARETSLVPLAHLTCVGATVPQLRRVVGAYAAAGIRNILALRGDPPGNVGGEW
LPTEGGLSHADELVELIRGLGDFTIGVAAFPDVHPSSPGLDHDIEVLVRKADAGASFAVT
QMVFDADTYLRLRDAVAARPHLPVTPGLMPVTNLRQIQRMSQLMGTPLPAAVVSRLEAVG
EDAAAVRAVGVEIATELAQRMLGEGAPGLHFITMNRSTATLEVHRNLGLASDMSLV
>A0A370HPV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia pseudobrasiliensis|TrEMBL
MYAISAHGRVNTKARAVPSVVRSLDIHSGARVPFSVEFNPPRDADGEARLWRAVREFERM
HPAFVSMTYGAGGSTKDRTVRITGQLAQQTTLVPVAHLTAVGHSVAELRALVGSYADRGI
RNLLVLRGDPPGDPLGEWHSHPEGVEHAEELVRIVRDLGDFHVGVASFPQGHHRSPDLAT
DTEHLAAKLRAGAEYSITQMFFDVEHYLRLRDRVLRHDPVEGAKPIIPELMPITSLRTVR
RAVELSGRELPAAVLRRLHRAAGDGPQENRAAVRSAGIEIATEMAQRLIAEGAPCLHFIT
LNFAKATTEVLTNLGYRVTAAPLSA
>A0A067NFL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pleurotus ostreatus PC15|TrEMBL
MKISQKIQQSTKEGKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQSMIGVETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPQGKDE
WEAVEDGFVHGIDLVKHIRRIYGDYFDIAVAGFPQHMLLPPDELAFEMKCLKEKIEAGVN
FIFTQMFYDVEIFIEWVKAVRAAGITIPIVPGIAPIQTWNGFVRATSLAKTIIPQSFTEA
LEPYKNDDEKVRAIGTRLVADMCRRILDEDLGIRGLHFYTMNLEKATKMLLEELNLVPRI
ETIKPLPWRQSLTPTRRQETIRPIFWANRAKSYISRTENWDEYPNGRFGDARSPAYGELD
GYGISLKQTVKDALKLWGQPETVADVSSLFARFCRGDLSALPWSDQPVAGETTAIAQHLA
KVNELGFLTINSQPAVNGARSDDKLFGWGPSNGYVYQKAYLEFFVNPTLLNILLSHIERD
GNITYHVINKRGDLRTNTQSEGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAYELGQQ
WARIYESGSVPNKVVSDIMNTYLLVNVVHNDFQDPEAIFRPFYQAGAEYITKIQSQAPVT
ADH
>Q5NLN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)|TrEMBL
MERILRENPNFVAEPFLGEKEPHISFEFFPPKNEEADKLLWQSVERLAPLKPRFMSVTYG
AGGSTRERTRATVTRIARETTIPAVAHLTCVNASRDEIDDIARDYWDAGIRHIVALRGDP
PGGERFQARPDGYANAVELVEGLKRIAPFEISVACYPETHPQALSPEADIEFLKRKFDAG
ATRAISQFFLSADVFLRFRDRVAAAGITAEILPGIMPTSNISGLRRMADSCGIAIPEKLG
RLMESLDKDDPSVKQMVSMAVTSDLCSQLAREGVDSFHFYTMNRAEITSALCRLLGRQPV
A
>A0A5K1K7S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ganoderma boninense|TrEMBL
MSYETRPEPTPESTSKIEDRGSFIERVDSPPSAPKPDAQNLNAKLANPLAGVTHEQLMAD
AVIFASTHGLAEYTATIQKGALVAQDPAAFESLPLLTEDDRVALRREITHKWDQPAMLYY
LVIMCSIAAAVQGMDEAVANGANLFFPGQFGIDPGPPGSGMNKNQWLQGLVTSAPYLCCA
FIGCWLTDPLNKWFGRRGTIFISAVFSFATCVWQGVTNSWPHLFVARFFLGIGIGPKSAT
VPVYSAEYVSDPFGVSCLCSSPHAG
>A0A0E3WBJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium lentiflavum|TrEMBL
MEFGPCGGVRPDGQCEMRPGDCAFGDVVPWSGVQPAPRPVRAPLVLTDFSATPFDRNDIA
ATAAVLASGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDRNRVVLEQELRG
LHTLGVETVLCVTGDGRGYDVRPDVTQTFDLDGPRLVALAASVGMIAAVPETPTAPPVHA
RPDRLVQKQRAGASLAVLNHVPFPKMIDEFMVAATSAGLSIPVIAAVAVFTDSVSAAVLQ
GLPGLELDQAVTEQVLDAADPVAAGIAAAVEEARALLCIEGVDGVNVSGLASASGGRVGA
EIKAEVGRLIREEVS
>A0A1I1I3W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas denitrificans DSM 6059|TrEMBL
MALSLKQKIQDPRQGVYLIGTTPPKMGTDKAQLETIAKKLLNRLHEIEYDGVVIYDIQDE
SSRISAPRPFPFKKTVDPREYSQLISQLSHLDVITYKSVAQRDESEFNTWLDETANKFKL
KNLVLVGSPSSTGNIKLSLPNAYKALSEDKNSVFLGGVTIAERHASKRNEHDRLLEKIDQ
GCDFFISQAVYNAQETIDLITSYSRSCRHKGISPKRIILTFTPCGGEKTLDFMKWLGISV
PEATKWRILDSNDSLNESIRICRDNLNQVLQSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKATMELNLAEKQIA
>A0A1G3K6C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium GWF1_63_6|TrEMBL
MTLPSIHPNWDLPPKGMTDGYSLEITAKDIDALREAAPTMAPDTPVAVTFLPGESLEARI
AAAKMVRALGFEPMPHFSARRLESGDDFETYLAAVVREADVHRCFVIAGDPPEAAGPYSD
SMALIRTGAFERAGIKAIGIGGHPEGHPNMTPDHCFAVLIEKCAEIEQRGMAPLIVTQFS
FDAAPVLGWLSDLRQRGIDAPVRIGIPGPAGIKTLMRFAARCGVGASASVLTKYGISITK
LIGTAGPDKLVDALASGLGDQHGKVRLHFYPFGGLTKTVDWINDYTARH
>A0A7Y5BVY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MAQTSSIPFLTRLASPPPLLFDGAMGTMIHARGVGFDRCFDELNLTHPALIADIHRAYID
AGAEIVLTNTFGANRYRLARHGLENRVGDINRAGVDLARRVILASFKNLYLAGDIGPLGV
RLVPFGRVQLEQARDAFREQITALVASGVDVLLMETFSDLYEILEALKAAREVSDIPLIA
SMTFTRDDRTLLGNPPAEVAQRLHEAGADVIGINCSGGPAQMLRILKQAHEAVPGARFFV
KPNAGLPEQVGGRIMYPAGPAYFGDYAHAFRRAGACLIGGCCGTTPEHTHAMRLALDTPL
PEREENGNSLTLIEREEVAPADQPTELSQKLSSQQFIVTVEMAPPRGLNTQKVLAAASML
QEAGADVINVSDSPMARMRMSPWAVANLIHEQVGVETILHFPTRGRNLLRVQGDLLAAHA
LNVRNVFVVMGDPTAIGDYPDAMDNYDVVPSGLVKLIKQNFNAGSDYSGTDIGQPTSFFV
GCAANLTPRVPAEEIKTLRRKIKAGADFALTQPIFDPQAAQTFLAEYAATQGALPIPVVV
GILPLANPRHAAFLHNELPGVRIPPEFLNRMEQTLDPREEGIRIAVELVEQVRPWVAGVY
LMPPFGRYDVAAEIVERVK
>A0A524JFD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MNRQGLLDHLEQSHHPLLSDGAMGTMLHAHGTSFDACFDQLNLTDPGRVAEIHQAYIIAG
ADIVLTNTFGANRYKLADHGLQNQVAVINRAGVDLAAKAITASQKRVWLAGDIGPLGVRM
VPFGRVTQDMAYAAFREQAQVLVDSAVDLLIIETMSDLHELLIAVRAARDAGDLPLIASM
TFTRDDRTLLGDTPVKVAKRLHTADVDILGVNCSGGPAQLLRIVRQMRDAVPGIRVWVKP
NAGWPEQVAGRIMYSATPEYFAESAWAFQEAGVSIMGGCCGTTPDHISAMRKAIDLGPPA
DFIVQEHLERLPSIGTALPPDQPSRLSKSLSAGHFTFAVEMDPPRGLSTHRLLAGAELLS
KSGADVINVADSPMAQMRMSPWAVCSLVQDQVGIETTLHFPTRGRNLLRVQGDLLAAHAL
GIRNVFVVMGDPTAIGDYPEAMDNYDVVPSGLIKLIRHNFNAGVDLSGSDIGEPTSFYVG
GALNLTSQDPDREIKVMRRKLRAGVNFFLSQPVFDPSSALAFVNRYNDVYGPLEIPILVG
ILPLFGERHAHFLHNEVPGISIAEPIFSDLSKAGKEAPKVGVQIAIDLIAQMQGWAQGVY
LMPAFNRYDLAADIIAAFHA
>A0A0G8EMS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLNTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGILISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>Q494D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blochmannia pennsylvanicus (strain BPEN)|TrEMBL
MSMFHATQQAVLNQYLAELQGNINVSFEFFPPRTDEMEQILWKTINKLSKLNPIFVSVTY
SAHSGTRNYTDKTIKDIKKRTGLIAAPHLTCINETPQALQTIAQEYWNNGIHNIVALRGD
QIKKNYQSSMYASDLVYLLKKIGNFDIAVAAYPEVHPEAKNAQSDLINLKKKIDAGANRA
ITQFFFDVEQYLRFRDLCVSVGIDIEIIPGILPIFNFRQLQHFITFTKVKIPHWIYVIFH
GLDHDLETQKMLGTFVAIDMIRVLLKEGVRNFHFYTLNRSDLTYAICHTLGIKNNKI
>A0A7C1JTT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomicrobium roseum|TrEMBL
MTDSPSSLVSTEAQIDTRFLCSLLRELRIEVLPNVDLSKVTSIVPRDATLTVTSSPAHGV
EGTLQTALALRREGYRVVPHLAARALRDRSQLAQLWHQYTSAGIDEVFVVGGDQERPAGE
FPNSLALLQTLVELEPPPTRIGITAYPEGHPHIPNDVLEADLLAKQAYAHYAITQLVFDP
DVLLNWLVRSRARGFTLPVYLCLPGTLRLDRLIRIGMRLGLGTSLRYLEKQRGLVGRLLT
GGLRYDPGDLLDGLARRPAAAHAGIVGVHWSSFNSVDSVVHWVLARRESLGCGQEGATA
>A0A7C2BE10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomicrobium roseum|TrEMBL
MAHPFLERLQRGPLLADGAMGTQLYERGVRLEQCFEAVNLRDPDLVVAIHRDYILAGAEL
IETNTFGANRMKLESHGLGERVRDVNRRAVRLAREAREITGIPVLIAGAVGPSGRILAPI
GTVAPETIRDVFREQIEALLEGGVDLLIFETFSQLEELRQAILAAREVSDLPLVAQMTFA
ADGRTMAGHTPDVVVQSLTELGVDAIGVNCSVGPRPMLAVLRDMVAANTGNIPLSAMPNA
GWPTVLGDRVIFGSSPDYFAEFAQEALELGVRILGGCCGTTPNHIAAMRRVLDEQRGTSV
SSGAAIRLEERVRPVTVLAPEGPTRLKQKLGREFIISVEIDPPKGLNPQKAIDGARILRQ
SGVEFINVADSPMARVRLSALGLCYLLQHEVGIETILHLTTRDRNLMGLQSDLLGAHALG
VRNILALTGDPPTLGDYPHATPVYDVDSIGLVRILTNFNNGMDAGGASIGQQASFTIGVA
CDPTRPDLDRELERLHAKLAAGAHFIMTQPVFDLDTWLTFVRKYEERYGPLGVPVLLGIL
PLQSYRHAVFLHNEVPGITLTEEALERMRRAGANGRAEGVAMARELVARAYEVVEGIYIM
PSFGRYEVAVEVVESLPQNRVRRVTS
>A0A561QVL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neorhizobium alkalisoli|TrEMBL
MDTKTAARDEFGLSFEFFPPKSEEMEAQLWEAVGELSAWQPGFVTVTYGAGGSTREPTLA
AVRRMIDDASLSTAAHLTCVDASKDEVRAVVDEYRAAGVRRIVALRGDPTTGIGTTYTPH
PAGFTDTSELVRMLVEYGDIDVSVSAYPEKHPESPDMAADIDTLKRKADAGAHRALSQFF
FDNDVFERYLEGVHKAGIKIPVLPGIMPIQNLTQLKRFAKRCGASVPEFLDRRFEGLDDK
PEQRAEVAADVAAEQIEDLMRRGLKDFHIYTMNRSPLVGAVLEQLGRKRADAKVVAAA
>A0A7W8FQQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. AZCC_0083|TrEMBL
MTFQSAATTVEELVAAANIEVIPLRGADEKALAIPPASTITVTCSPKFGLERTIEHVVRA
RESGHRVVPHLAARMVEDKAQLERFLDILSSEGVDDLYVIGGDGADPVGKYSEAFHILEA
IQELGHDLQRIGVGCYPEGHPHIADDALLDALQRKQPYADYMVSQLCFEAATFTGWLRRT
REAGISLPVRVGVAAPLQTRKLIELSLKIGVGSSVKFLTKQHGFVGNLLLGRSYTPEALI
SQIVDETGFRELGIEGLHLFSFNQIDATVEWQHRISAAATA
>A3W5X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp. 217|TrEMBL
MTTPRISFEFFPPKTLEASFRLWDTIHTLSPLDPRFVSVTYGAGGTTRELTREAVGTLHK
ATGLNVAAHLTCVDASRAETLEIAEQFAAAGVSEIVALRGDPPKGSNGFVAHPEGFADSC
ELISALADTGKFTIRVGAYPEKHPEAVDQKADIDWLKRKIDAGASEAITQFFFEAETFFR
FRDACAAAGINAPIIPGILPIENWVGARKFARSCGTQVPAWLDEAFDKAIRDNRHDLLAT
ALATELCSDLLEGGVEDLHFYTLNRPELTRDVCHALGVTPKVTLRDVA
>A0A016XF69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hylemonella gracilis str. Niagara R|TrEMBL
MSEQTKPQSLPLSIEFFPPKTPEGVEKLRAVRQQLYALQPEFCSVTYGAGGSTQEGTFAA
VKEIMAEGRDAASHISCIGATQATMRENLAALKGMGVKRLVTLRGDLPSGYGAGGEFHYA
SDLVAFIRAETGDHFHVEVAAYPEVHPQARSPEADLQAFAAKVKAGADSAITQYFYNADA
YFRFVEDADALGVTVPIVPGIMPITSSAQLMRFSDACGAEIPRWVRLRLQGYGDDTASIK
AFGLDVVTELCEQLRAGGAPALHFYSMNQSAATLEICRRLGLV
>A0A3N7DTK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquitalea sp. FJL05|TrEMBL
MSEQKKTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGHAAAPHLSCIGSTRENISAILNEYRNHGIRHIVALRGDMPSGMVAAGEFRYANELV
EFIRSEHGDHFHIEVAAYPEFHPQSKSAEDDLNNFVRKVKAGANSAMTQYFFNADAYFRF
VDEAQARGVDIPIVPGIMPIANFGQLCRFSDMCGAEVPRWLRQRMQSYYDDTASIRALGL
DVVTELCDRLLANGAPGLHFYTLNQAGLVSTVWQRLGL
>A0A0Q7KKY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium sp. Root472D3|TrEMBL
MASDDRSLVAALRAPAPSFSFEFFPPKDDAGEDVLWQTIADLEPLDPTFVSVTYGAGGTS
QERTVRITSRIAEQTGMRPVGHLTLVSQTKGEIESVLKQYAAAGVDNVLALRGDPKGGPR
APWEQHPDGMTYAIDLVELARQLGGFEIGVAAFPEGHPDAASLDHDAEVLVAKARAGADY
AITQLFFRASDYFGLVDRVRALGSDIPIVPGIMPILNFAQVARMAELSGAAMPPEVLEQI
EPIADDQGAVRAKGIELATQLCRDLLDGGAPGLHFITLNRSRATREIFDRLRADELI
>C4WF86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella intermedia LMG 3301|TrEMBL
MMGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGST
RERTARTVARILKETDVKPAAHLTCVDATREEVDRVVREFASLGVNRFVALRGDPAAGIG
EKYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATR
AITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPAWLAERF
DGLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKAEAA
LEMA
>A0A401WHA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter pasteurianus subsp. pasteurianus LMG 1262 = NBRC 106471|TrEMBL
MSLSRLSVELIPRSAEALAADVATVKAAFPAADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQPGLEEILVVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMQGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLDANIQFAQTVLKELAQEKGKAYLMPVRIKLEQY
LPALLDAVA
>A0A1L9UXS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus brasiliensis (strain CBS 101740 / IMI 381727 / IBT 21946)|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQGKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEVADGGFRYAKDLVTYIRSKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDKGIHVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELKLMPSEETP
LQRPLPWRPSLGLNRREEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTNLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIEELIARIEKNG
DLTYHAVSKNGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDSWHLVNIVNNDFHNTSNLFDLFKDLDVRELDAEIPVENGEPK
AHANGATNGTTNGATDGAAPELAVKN
>A0A1C4WWL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora chokoriensis|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTDAGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATDTTLLPMAHLTAVDHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWIRHPEGVDYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAQFVR
KCRAGAAFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIATIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGVEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARV
>A0A8C8CAY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
MFSPVCDGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTESGDHWFSLEFFPPRT
ASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLT
CCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYATDLVKHIRCEFDDY
FDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVRDCRAIGIT
CPILPGFVFQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGIEQAVGMCRVLL
ESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHPKRKVEDVRPIFWASR
PKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEELTSEQS
VYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVNRRGVLTINSQPSING
KPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGQNTTN
AHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQWAKLYEDESPSRMIIK
YIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEQTAEQPNDEQSDKEQPG
K
>A0A7X8MGL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp|TrEMBL
MNLAELYKKKKPVISFEIFPPKLDTPLESIFGTLEQFKELKPDFISVTYGAGGSAKDRTI
EIASKIKNEYHIESMAHFTCVGHSKTEIDSLLENLHANNLENILALRGDPPADQPDFDFS
KNVYRYASELIGHIRNKSNFFCIAAAAYVEGHSDSKRLKDDLIHLKHKVETGVDFLVTQL
FFDNRLFYDFLDKTSAIGINCPITPGIMPIFKAEQIKRIASLCGASFPAKLVVLMDKYGD
NPEDMRKAGIEYASTQIRDLIDNGVDGIHLLTMNRPKSSKTILENAGLL
>A0A8C8EJL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
MVNQVQRVEDTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGFVFQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRN
YGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVNR
RGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAPKGL
SDHEKQDSIV
>A0A7V2W242|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MVSRFKEALGSGKFVITSEVAPPKGTNLEKMQHHIDLLKDKVDGINITDHQSSAMRFPSL
GGCLAVLESGGEAIMQMTCRDRNRIALEADLLFAYSRGVRNVLCLTGDAVVVGDHKEAMG
VFDLDSLQLINAVHALAGGKDLGGNDLDGAVEFCVGAIVTPEAQPLEPQLIKFEKKVEAG
AEFFQTQAIYDLDNFKRFMDYARKFKTKILAGIVLLSSARMAKYMTANVPGIFVPDDLLD
EMSAAPKEEMLAKGIEIAGRTIAALKNETICDGVHIMAIGREETVPDILKAAGM
>M0LVR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halococcus hamelinensis 100A6|TrEMBL
MSVERHSGTAAEVTDELLTGPRFELMPFESFEGQLEHLPDGATIAITTSPQLGLDATVEQ
AEMAAARGFDVSPHIAARYVRDEDHLTEIARRLTEAGVTDIFVPGGDREEPAGEFESAYE
LLTTLSDIEYSFEEVGITGYPEGHDFLSDRVLADAMEKKAPFATYIVTQLCYDPEAVIEW
VEEVRDRGIDLPIEVGIPGVMKYQRLLSISQKVGVGDSVRFLKKTTGIVGFVRQLVGSRG
KYTPDDLIEGLTPYATDPEYGIQGVHIYTFNQTSDTESWRWGALNQ
>A0A3D2AX16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MQQFNCTIKFHMGNSSLIERLSRGSLLSDGAMGTQLYAQGITGVPIEAANLERPEIVKAI
HRSYLQAGSELIATNTFGANSSRLASHGISSQTEELNRTGVALAREAIRLNGQQAWVAAA
MGPLAVDSFAAEILGSAAAHNVFAEQASILTESGADVLILETFTSLTQLRLALDAVRSVS
NLPLMATLTFNNDGLTPAGDTPEEIATTLNESSLLAIGANCSIGPDLLRSVIERMAQNTN
LPLIAQPNAGLPSYVDGQLQYTAESSYFAEVLKDIAYSGATILGGCCGTTPKHISSVRDK
IKGVIPQRTFAKIPQAPQKHSKHEDEGKPATGLAEKIAKGEFVVTVELSPPRGFDISDTV
DKLRGIAGHIDAVNVADSPRAQGRMSALATGSLIQSKLGIESIMHAAIRHRNLLALHSDL
LGAHALGIRNVFTVMGDIPQSGDYPQATAISDVTASGLIRLMSGFNNGVDANGREIDSPT
SFFIGAAFNFNAPDIDRELKVLERKIAAGAHFLLTQPIYSMEQFDRVYSVLGKFPVPVIL
GVLPLRNTRHALFLHNEVPGIFVPGDIVKRLEQAGDKSASIGIDISKELLQELSGKIAGA
YFMPPFERFSVVQETLEGLNL
>A0A7C3IJB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSEASRLQQAFAAGKFVVSGEIGPPKGTHIEEMLHHIDALKDKVDALNVTDNQSSVMRIS
SLGVCQLIKEKNGEPILQMTCRDRNRLALQSDLLSASVLGIKNVLCLTGDYITIGDHKEA
KPVFDIDSVQLIQTIRQLEQGRDLAGNELQGAPKFFVGAVVTPEADPIEPQLLKFEKKVK
AGADFFQTQAIYDIENFKKFMRYARQFNTKIMAGIVLLVSAGMARYMNQNVPGIFVPQEL
IDEMASAPKGKALEKGIEIAGRMIRQLKDEKICDGVHIMAIGREGVIPDILSAAGLNGAG
>A0A7X8R7W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp|TrEMBL
MLKEKIVNRRSGIITYGITPPKKNNTLEKINEVARKQIERINSLDIDGLVLYDLQDEKDR
NPKERPFPFLETIDPYTYSTEYLKDIKVPKIIYRCVGKYTQDHFCQLIKPVDGQDAFSVF
VGAASQNQTVHLKLSDAYRIYKEINSDLVLGGVLIPERHMKNADEHLRIIQKIKKGCKYF
ISQAVYNVEAAKDFLSDYYYYCKDNNLNMVPMIFTLTPCGSAKTLEFMKWLGISIPRWLE
NDLMNSEDILNKSVSLSKSIFGSLMDFCAEKEIPIGCNIESVSVRKVEIEASISLARDIK
AMMKDL
>A0A7L4YJ39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epidermidibacterium keratini|TrEMBL
MSGPPHRSIADALAAGPTWSFEFFPPRDAASEAQLWEAIRRIEQLHPSFVSVTYGAGGTT
RDGTIRIVDRMVAETTLLPLAHLTAVEHSVAELRQMVGHFAAGGVRNVLALRGDPPGDVE
GEWHAHPEGIEYAAELVRLVKASGDFTVGVAAFPHKHPRSPDIEADARYFVEKCRAGAQF
AITQLFFEAEEYLRLRDRIAALGCDVPIIPGVLPVLSPATIERAPKLSGAPFPPALAEEF
AACGDDKAAVRALGIERATQMCELLLREGAPGIHFITMNRSKATQEIWTNLQGVTAAGLG
G
>A0A7C0ZL73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKSGSNLEKVLTAGHFAFTGEVGPPRGANVEVIREKAKFLKGNVDMANMTDNQTAMVRMS
SWAGSLILLEEGVEPNYQMVCRDRNRIAMQSDILGAYALGIRNILCLSGDHQQFGDHPKT
KGVYDVDSIQLISIVKKMRDEGKFLGGDDLNGAPKMFIGAAANPFGEPFEWRVHRLAKKV
AAGADFIQTQCVFNMERMREWVHQANEMGLTEKIYILPGVTPMKSVGMAKYMKNNVPGMD
VTDEIITRLQGVEKKKAADEGIKIACEQIEEFKEMKGIAGVHLMPIEWEHRVPEIAERAN
MLPRPQV
>A0A1C5R8P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Faecalibacterium sp|TrEMBL
MKDVREILKKRPLLFDGGMGTYYKAKPGQECEQANLLDPDGILTVHRAYLEAGADAIKTN
TFGLPRMAAAQNPMWEAMADEGWKLAAQAAAKTSAAVFADLGPAPDTEALPAAQIYTALA
ERFAALGAKNFLFETLSSDAGVAEAARQIKEAVPDAFVLVSFAVLPDGYTREGRHCAELV
RSMTACGAVDAVGLNCVSAPGAMRALVQQLGETKLPLAVMPNAGYPVVTRTRVQYQGKPE
YFARELARLAAEGVRILGGCCGTTPAHIAALRAALDALPETLPAAPAAAVSTAAKPEVEK
DDAFLRKLNAGKKVIAIELDSPKDADLTGYLDGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGLNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPLTVFGALNLNARNFDVELRRAQEKLQNGMSGFL
TQPVLSAQAVVNLKKTRETLGEKAKILAGIMPVVSQRNAIFMENEVNGIHVDAEIIERFA
GLDRVQGEELGLEVSVKAAQAAAPYADGFYLMTPFNRIALMERLIARLKDEGIAD
>A0A7W8S8J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. CI2|TrEMBL
MTFLTMNPIELSFEFFPPKTQEGIDKLRATRAELVSLKPKFVSVTFGAGGSTQQGTLDTV
VDMAKEGLEAAPHLSCIGSSKDSLRAILNEYRAYGIRHIVALRGDLPSGMGAVGELRYAS
ELVSFIRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFAHKVKAGANSAITQYFFNADAY
FRFVDDARQLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRA
FGLDVVTALCQRLLDAKVPGLHFYTLNAAASTKAICERLAV
>A0A7V2QLM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSKLKQALESGRFVVTGEIGPPKGVDLDKCLQDAQMLREHVTAINVTDLQSAVLRIGSLA
VSARLIERGLEPVYQLTCRDRNRLALQSDLLSAWSLGIENVLCITGDHPILGDHSEAKPV
YDLDSVQLLKAASTLNQGHDMAGHELESAPSFFLGAVVTPAAEPLEPQIIKMKKKIEAGA
KFFQTQAIYEPEKFEQFMSRIQGYKVPVIAGIVILKSAAMAKFMNANVAGISVPESIIRE
MEETAKEDRRKKAVELAARIIRQVEPFCQGVHIMPLGWDELVPEIISEVGVIP
>A0A7V3W980|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAKFKQALQSGKFVVTAEVGPPKGTDIKEMLHHIDLIKDRVDAINSTDNQSSVMRISSLG
ACALIKQRGGEPILQMTCRDRNRMALESDLLAANVLGIDNVLCLTGDYISVGDHKDAKPV
FDLDSVQLIQAVRLMEQGKDLGGNDLNAPVKFCCGAIVTPEADPIEPQLLKYEKKIRAGA
EFIQTQAIYDIDNFKKFMAYARKVNKDTKILAGIVLLASAGMARYMNSNVPGIRVPKELI
DEMAGAPKGKALEKGIEIAGRMIRRLKDEKICDGVHIMAIGREGVVPDILAAAGL
>A0A5I3B5G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Adelaide|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7C4ZT20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTAKAQHLLAESAERVGKPRVSFEFFPPKTDALEAQLWDSIRKLEPLAPSFVSVTYGAGG
STRDRTHRIVARILAETTLKPAAHLTCVAASRAEVDSVLRDYRRAGVKHIVALRGDPPGG
VGLPYLQHPQGYRSAAELVEAAARIGGFDISVAVHPEKHPASPSFDHEIDNFKKKLALGA
SRGITQFFFDPDVFLRFRDRLARAGVYAPVLPGIMPVTNVKGLKKMADACGAALPRWMVH
LFEGLDGDPETRRLVAAVTTAQLCARLSAEGVHDFHFYTLNRADLALAICRILGLRAKEQ
VV
>A0A1T1R9W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. vitiscarnosae|TrEMBL
MIPTDTPSGASTITDAYSLEVSVKDIGALTNAAPRILPGSDMFIPYLPGQTEAARLAAAQ
RVRRLGFEPVPHLSARRIGSLEELQAAIARLVGEADVTRCLVIAGDPSTPKGPFADSVSL
IETGVFERSGIRTIGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
IVMTWLEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLVSRLTEAHGDVRLHLFPFGGIAQSVEWVAHYRSCEASQDRVSSVAAD
>A0A2E4BXF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTKVVNALENRKSKPLIISDFSPPKTLKLDFLNDVRTLDVDFIFVAYNPGRSVRIESSVL
AYVIFQETGKEVIFSMVTRDMNKLALQSHLLGARFLGLENVVIAGGDSFGXSESSLIKSV
NDYKPTELMRAVQSMNLGKDFRGRDLSDPIDICVGATIDLGRDIYQEAFLTYQKVRSGAQ
FFITQPIFYPSQISEFLETYWEISGTNLIEPVFWGLQILTRDGVTFSSVPMEFRDRVESG
EDGVDIALSQWETLNRFGIDALYLVPPIARGGARDYNVAARFIKQLN
>A0A2W4RCZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MNQFRLSRRPDIGNKIRVSFEFFPPKTDEMETRLWETVKRLEPLRPRFVSVTYGAGGSTR
ERTARTIDRILAESALMPAAHLTCIDATRETVDEVIRQFVDLGVTRFVALRGDPSAGVGT
RYRPHPGGYANGAEMVAALRRHGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDIYERYVERVRRAGIYIPIVPGILPVHNISQVANFSARAGAHVPAWLRERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRADPAKSS
LGSAAA
>A0A432SLX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp|TrEMBL
MFDTLIDKLHHGSYITLETTPGHSPQFTPIIDTIEALSLHRLVDGFSTTDNPLAKLKYNA
LFAAKLLQERFNKPVLATMSMRDRNRIALQSDLLGANESDIRTILALTGDPAKISDQPNS
KGVFESDSSLLLNMIACFNSGIDYAGKPLALKPKPIYPFSVVNAYAKNPKTLQNKMQKKI
LNGALGIITQPVYNIDNAKVLLELMEHANKECCLEGKDVQLVFGVFPITKLRTAQFLSSH
VPGINVPKSWIEKLRGAHDISEEEEYKVGFELSKTLFDALRALHPKIHLMCANQFSVAKE
ILR
>A0A523X4H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKSKSQLEKIMESGQFAVTGELGPPASADPEVIKRKAKYLKGCVDAVNVTDGQTAVARMA
SWAACLLGKEEGLEPTVQMTCRDRNRIALQMDILGIAALGINN
>K6X7R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliiglaciecola lipolytica E3|TrEMBL
MVSYAQGIESLNQSLSELSGINVSFEFFPPKTEQMEQTLWKSVERLAPLKPAYMSVTYGA
NSGERDRTHDVVKRIQNETGVAAVPHLTCVDAGREELIQIAKDYWQSGIRRIVALRGDLP
PGTNNTEMYAADLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATQAIS
QFFFDAEVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLKRFAGFTNVHVPNWLHKMYDGL
DQEDQTTRNLLGASIAMDTVKVLAKEGIRDFHFYTLNRSELSYAICHLLGVRAQNG
>A0A2W4QX81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTEANTAAVPVDGAELKRRIVEVMRGASTEVTTHDDGILPEIVRELPPDCTVYVAHTPKA
TLDDVIRVAARIQSMGVRACPHIVARRIESEQALRNALRAARDAGIETILALAGDRDPPA
GPFRSSLEVLATGATVDAGIKSIGVAGHPEGHKQVETPVLWEALREKQAFAERTGTQVRI
VTQFAFEPEVFLNWEAELRSNGINLPVYFGLAGPTPLTKLIKYAMACGVGASLNALMKNT
SLLGHVTGTAATPDEMLTGIVRGMIQRDTKLLVKPHFFALGGAVATARWMRAVAAGEFDL
KPNSDKFVMRA
>A0A2D9HU54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSGQIEEQSRLERVLRSGRIAVTAELNPPDSASPDSVYGNALVLASLCDAINATDAAGAN
VHLSSLAISALLAKAGYEPVMQMSCRDRNRIAIQGDLLGASALGIKNILCLTGDGVQAGD
HPDAKPVFDLDSVTLLKTAKRMEEKGTFLSGRKLHTSPHFFLGAAANPFVPPFDFRPLRL
KKKIDAGAQFIQTQYCFNVARLKTYMKEVNDMGLTDKAFVLIGVGPLKSAKSAEWIRSNV
PGVVIPDGVIKRLKGAQSQANEGKKICLEIIQEVMEIKGVSGVHVMAYRQEELVAELITE
SGILDHRAKKYQKGKA
>A0A2W4PRA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
EEVNEVVRAYWEAGVRHIVALRGDPAEGIGAAFRPHPGGYEGSPELVAGIRAIADFDVSV
SAYPEKHPESVSIDADIELLKRKVDAGASRAITQFFFDNDVYFRYLDKVRARGIDIPIVP
GILPVQNFKQAANFAARAGASVPAWLANRFDGLDNDVETRRLIAAAVAAEQVIDLVDRGV
TDLHFYTMNRADLVYAICHLLGLRPTTAEAEPVAAVAVA
>A0A3B9HFV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKVFDNDINFSQLRRSVLMPSVTELLTQPRSRPFVVLDFSPPRGGIPHLLSDAFSLTPDL
FSVAYNPGKSVRANPIMVAHWIQNNTGIPAVFTLATRDMNKRALQGILLGAQLIGLDNVV
SVMGDELKSSGKLSQKTISDFTASGFVSSIKQMNTRVDFRDRFLRHPTGFCVGATIDLSR
DWSGEIPLTRKKVTAGADFFLSQPVFDTSQPEQFMERYFKETGCRLETPVMWGVQVKVQD
SVSLVPVPDWVHNDLEQGRSGFEIALQIISEHTDYGFDTFYLVPPILRGGTRDYESAQAV
IDEL
>A0A2E7HAQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKKFSIEILPKQKSKISELNSDFFKDVYITHIPGSSLNDLIDTAKEVSVYGLNPVPHIPA
RSITDENTLNETLESLKEVGVKDILAIGGSVKDKVGKFDSTLDMFSTGALNNIGFKSVRI
AGHPEGNPDDKNSIQSLKNKLIWLKENKFSASIVTQFCLSPEITNYWIMETKKLIKDFGE
DGTKIIIGVAGPSKITTLIKYAKVCGVSSSANFLMKQGLDVTKLIKHSPTDLIEKLDGFD
SLHFFPFGGIKELDDWLLKQK
>A0A4R4FHU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Extibacter muris|TrEMBL
MKIKEILKDKEPHISFEVFPPKTDAGYESVLSATEKIAALKPSFISVTYGAGGGTSKNTV
NIASHIQNDLGVVSLAHLTCASSTKDEVRQVIGKLKEEGIENVLGLRGDIPDDVQFPVSN
QYKYAYELIQDIKSQGSFCVGAACYPEGHVETEHKKDDIENLKNKVECGVDFLTTQMFFD
NNILYNFLYRIREKGITVPVLPGIMPVTNSKQMKRICSLSGTALPERFRAIVDRFGENPK
AMQQAGIAYATDQIIDLIANGINNIHIYSMNKPEVAEAIMYNLSEIVKV
>A0A6I1P8D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudactinotalea sp. HY160|TrEMBL
MSTAGLFSVPGTTPRVSFELYPPRSPAAQERLTRTVAELAAARPDFFSVTYGAAGRTHAT
SRGLIRQILAETDVTPIAHLTCVGASREELRVTVEELLEDGVRDVLALRGDPPTGGAPWE
PHPRGLTRAAELVGLLREIESERFELAEGQPRPLSISVAAYPARTFQAAQGSVLAAPRDL
EALHAKQEAGADFAITQLFYSAPEYAAHVEAARAAGIRLPIVPGVIPLTDLARLQRLTQL
TGVPVPEALELRLSAARDADEQYRIGLAASIELVEELLAVGAPGLHLYTFNTSRAALDLL
RGAGLREPAPSTSAAHR
>A0A7K6YQX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alca torda|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVAGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A852HMG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nicator chloris|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7R9APV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Timema shepardi|TrEMBL
MRADRLCVASILGFKNVDAGANFIISQIVFNAVCFSQFVKDCRNIDIAVPILPGVMPVQS
YKSLERTSSICHIPIPRAILDAVKPIEDNDDAVRNYGIHQAVQMIKEMFSLGCATGVHFF
TLNR
>A0A336K6B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas pentothenatexigens|TrEMBL
MSDLPQQLPAISFEFFPPKTEEMERNLWQAISRLAPLHPSFVSVTYGAGGSTRERTHATI
ARILKETDLTPAAHLTCVDAPCADVDEVVTRYHDIGVRHIVALRGDPTTGLGGTYTPHPQ
GYRSSADLVASIKRRYPDIDVTVSAYPEKHPESTGFDADLDILKAKVDAGATRAITQFFF
DNDLYFRYLDRVRARGIDIPIVPGILPVQNFKQAAGFAARAGASVPDWLAKQFEGLDDDP
DTRKLVAATVAAGQVHKLAKHGVSNFHFYTMNRADLVFAISHLLGFRPQPARQAA
>A0A3B7A225|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dechloromonas sp. HYN0024|TrEMBL
MTTDISIEFFPPQTPEGVDKLRTVRAKLAELKPSFFSVTFGAGGSTRERTFAVVKEIAAE
GHDAAPHLSCIGSTRDNIREILNEYKAAGIKRTVALRGDLPSGMAETGEFRYANELVEFI
RAETGDWFSIEVAAYPEWHPQARSPKDDMDAFVRKVKAGANSAITQYFYNADAYFSFVDE
AQARGVDVPIVPGIMPIVGFTKLARFSDACGAELPRWMRKKFESFGDDSDSIRAFGLDIV
TELCERLLQGGAPGLHFYSMNQATLTTEICRRLG
>A0A143WP85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tremblaya princeps|TrEMBL
MVNVAGSSPVRCALRVMPGLSFEFFAPRSHAGTIRLMCAQQVLSRFVPRFVSVTRSASLR
QHAHIETIASTLSVFPRTAPHVLFCQCPRALARELRAYELLGIRHLVLLRGDNGIAPGEL
GAPELVSLVRRSYGEAFYIDVAAYPDGHPMASTVFDDVRALARKVRCGANSAITQCFYNP
DAYYRLQDELQRLGVSLPVTPGIMPVLSHAYMSRFILPSGVDVPAWILKRLEALRYCSAS
VLEFGTDVALSLCESLAARGASDFHLYTMNDHRAVWRVCEHVLGSAAACHRSCA
>A0A512HD71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciceribacter naphthalenivorans|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYKRAAVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDEAKFLSGRKLSTPPQVFLGAA
INPFAPPYDFRPYRLAKKIQAGAQFVQSQYCFDVPMFREYMKKVRDMGLHEQCFILVGVG
PLASAKTARWIRSNVPGIHIPDSVIKRLEGAQDQKREGKQLCIDIINEVKEIEGVSGMHV
MAYRQEEYVAEIVHESGVLKGRKPWKREASPNDALVAERLERIREEKVEDQQQMAGLAAR
SQPKNAH
>A0A1Q8LUE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. Ae717_Ps2|TrEMBL
MTTSSASTVTERISVDRPFFAVEFFPPKDDQGEAELWRAIRRLEVLDPAYVSVTYGAGGS
SRDRTVRTVERIATDTTLCSMAHLTAVSHSTDELRHVIGSLAAAGVRNIMALRGDPPGDP
LGEWVAHPEGLEYADQLVALIKRSGPFCVGVAAFPYGHPRSADLDADTERLVGKFRAGAE
FAVTQLFLEPEGFLRLRDRVAAAGFDQPIIPGIMPLTSEKTFRKGPELSGSPLPGALVER
LAPYSGDAAGFRAAGMEVTGELCERLLAEGVPGIHFYCLNRSTATTELVERLGLAPRHEG
ARHSTPA
>A0A2N7Z7Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GW456-11-11-14-LB4|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISTMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A847MU99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Intrasporangiaceae bacterium|TrEMBL
MAHGLPSRLERPAHMTASIPANLRDAAASISFEFFPPKDDAAEIALWQAIRQLEAVRPAF
VSVTYGAGGSTQDRTVRVTERIARETTLTPLAHLTCVNASIAQLRQVVGQYASAGVRNVL
ALRGDPPGDVRGPWVRHPEGLDHADQLVSLVRSLGDFTVGVAAFPDVHPESRDLDEDVET
LIRKADAGATFAVTQMVFDVDTYLRLRDRVNAHRDLPITPGLMPVTNLKQIARMSELMGT
PLPAAVVSRLAAVEDDPVAVRAVGIQIATEHAQRMLAEGAPGVHFITMNRSTATLEVFRN
LDL
>A0A178XSW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer glycinis|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMETQLFQTVADLSSFAPAFQTVTYGAGGSTKAR
SLTTVKRMIGEMGLKNTAAHLTCVGAPKAEVEAVVDEFVACGVRHFVALRGDPQGGIGSA
YEPFPGGYENAAALVKALRARGDFEISVSAYPEKHPESPDVAADIDMLKRKVDSGATRAI
TQFFFDNDDFERYLERVRRAGVQIPVVPGILPINNLTQVIRFAGLCGSKVPEAIISRLAH
LDDQPEERFKEASHIAAEQIVDLARRGIRDFHLYTMNRSPLIAAVCDLVGYARRPTQRRA
APSYQAVATA
>A0A2E7KGF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia sp|TrEMBL
MRISEIYRSGTFGLSVEIFPPKNESGDAELFRTLEELVRYKPAFVSCTYGAGGSTSKRTI
ELCDTIQKDLHSTATAHFTCVGSTREQLVDWLKEASEAGIGNIMALRGDPPKGEETFIPA
DGGLKYASELVTLIRENFPKMGIGVAGYPEVHPEALTPQADLENLKRKVDAGADAIYTQL
FFNNQHFYRFQERCAQAGIDRPIIPGIMPITEYRRIQRIMSMCSSEFPAELVGRLEAAQD
DLDAQFEIGVEYAIAQCQELIDAGVPGMHFYVLNRSQACKRIFDALGWHESVA
>A0A2G7T7H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. B5|TrEMBL
MSFPISFEFFPTKTPEGAAKHVQVRKNLYARKPQFCSVTYGAGGSTQAGTFNMVRDIQSE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPHSDLEAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A0U3TNH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea vagans|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFLSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIARDYWENGIRHIVALRGD
LPPGSGKPEMYGADLVELLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNAMFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPPVLA
>A0A259GCA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium 17-61-76|TrEMBL
MSQRTFSFEFFPPKTAEGAEKLRATRAQLAQLKPKFFSVTFGAGGSTRDRTLETVREIQA
SGSEAAPHLSCIGSTQDNIREILNEYKSQGIRHLVALRGDLPSGTMDAGEFNYANELVSF
IRAETGDWFEIEVAAYPEIHPQARSWTDDLANFKRKVDAGADSAITQYFFNADAYFRFVD
EARALGVAIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLASIRAFGLDV
ITDQCERLLAGGAPGLHFYTMNQAGPSTTIWQRLGL
>K4KLH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Simiduia agarivorans (strain DSM 21679 / JCM 13881 / BCRC 17597 / SA1)|TrEMBL
MSDDIRISFEFFPPKTAEGKAKLYQVRQELQRFDPDFYSVTYGAGGTTRDTTRGVVKSLI
EQGISAAPHLSFGGDDEETVGTLLADYKSFGVDRIVALRGDLPSGMGGHSQLVYANQLVA
FIREKFGDHFHLEVAAYPEIHPEAKSYSDDIRYLKGKFDAGANSAITQYFYNPDAYFHFI
DQCQAIGIDSPIYPGIMPIINYRNLARFSDSCGAEIPRWLRKKLESYGDDSEALQDFGVD
LVSELCQTLLENGAPGLHFYTMNQTGPSARVLDNLFGDDD
>A0A559HUX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. NML180780|TrEMBL
MRGTFAPTRLSASAPIDRVGEDTTQQRRRTRTALSFELIPPRHGADEGKLDELIAGLAAY
RPDYVSVTSSRRSDWLTGTAALIARVAETTNLRPIAHLACTAGTREELVTWIRTLIDAGV
RGFLALRGDLPETGMPADHLQHATDLLNLIQDVEDEEAFRLAAGKLALSVACYPSGHAES
KNFDEDLDVLLSKQRLGADFAITQLFFNAQDYLDFVEVARLAGVRIPLIPGIMPMTSLKR
VQRMGELSGIEVPECVARTLAQATTPEEEYELGMQMSARLANTILDAGTGGLHVYTHNNL
AVTQDLLSRIGIPQRADHSPQ
>A0A136NFY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium OLB10|TrEMBL
MKVTEHLRQSKKTLFSIEVLPPLKGKSIKSIFNAIDPLMEFKPPFVDVTYHREEFVYKKR
EGGYLEKISIRKRPGTVGICAAIMNHYKVDAVPHIICGGFSKEETENALIDLNFLGIDNV
LLLRGDSEKHEQHFSPEPGGHSYAIDLVNQVVNMNSGVFLDDDLKGVEPTSFCIGVAGYP
EKHFEAPNLNTDISNLKKKVDAGAEYIVTQMFFDNEKFFSFVKKMP
>F7KMK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 5_1_57FAA|TrEMBL
MKTTELFQNKSVLSFEVFPPKRTNPVDTIYKTIDSLKDLNPDFISVTYGAGGSENCKATL
EIASRIKNEYGIESVAHLPCISLTKSDVRRQLSDFKEAGIENILALRGDVPSCGYVPGDF
RHASDLIAFIKEHGDFNVLGACYPEGHQESADIFDDIKNLKTKVDAGASHLITQLFFDNH
YFYRFRERASLAGIQVPIEAGIMPVTNKKQIERMVSLCGVTLPHKFSAMMERYEHNPDAM
RDAGIAYAIDQIVDLITHGVDGIHLYTMNNPYIAARIYEAIHQLLAA
>A0A822UXQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium tumefaciens str. B6|TrEMBL
MHKLPDISAASIIPASIEASPAQVLGASDLAGLFPQGVRVYLTDTGAASQERLVDAAGHL
RDLGYEPVPHLAARRIPSRTGFEEQVRRLAGEAGVTDVLVVGGGVDRPAGPFASSMDMLS
SGIFDRCGIRQIAIAGHPEGSPDFNDDTAMAALRLKRDFAERSDAAMRIVTQFGFDPARF
IAWAEGLTASGIDLPVHIGVSGPAKMTTLLKYAALCGVGNSIAYLKKNALSLTTLAKGHS
PESIVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGGADRSASQDSIAG
>A0A822UZU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium tumefaciens str. B6|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNAEMETQLWETVAELKKWDPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLSTAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYQ
PHPEGYENAAALVKGLREIGDFEISVSAYPEKHPESASDAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>R4G603|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus flavithermus NBRC 109594|TrEMBL
MGLLNDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIDAGAEVIQTN
TYGANYVKLARYGLQDDVKKINEAAVSVAKQAAKGRAYVLGTIGGLRSTNKSTISLEEVK
RTFREQLYVLLSENIDGLLLETYYDFEELQTVLSIARQETTLPIIAHVTLHDIGVLQHGM
PLADALYQLEQLGADVVGLNCHLGPYHMLRSLEEVPIPSRAFLSVYPNASLPQYRDGRFV
YETSEQYFEETARAFRDQGVRLIGGCCGTTPKHIAAIARALSDRTPVYKKEVKQRHTITV
QEAEQTSAPSLADIARMRRSIIVELDPPKKLGLTKFLEGAKALKEAHIDALTLADNSLAT
PRISNVAVGTIVKQQLNMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRL
EKKIECGAHYFLTQPLYSEKQIEDVYEATKHLSTPIYIGIMPLTSARNADFLHHEVPGIT
LSDDIRARMAACANDPIQATKEGLAIAKSLIDAAFDLFQGIYLITPFLRYDMTVELVRYI
HEKERLAKERTVYYG
>A0A836VCY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Melainabacteria bacterium|TrEMBL
MPKKETRRHMTHPFLKELAKRPLLADGGIGTLLYARGASPEASFEHLNLTKQDEIQKVHI
DYINAGADVIETNSFSANKYRLATFGLEADTHKINLWAAKVARNAREVGGQPVFVAGSVG
PTGKLMAPIGDVTAQDLKDAFTEQMEALLAGGVDLFIIETMSSLEETAIAVRAARAVSKL
PVVAQMSFSPDGHTLLGVTPEDVVKLYVELGDDAPDVIGINCGAGPGPVFDSLLRMSHAL
KERGVDPSKLNYSCLPNAGQPSLSGGRYQFMSGPDYCASYVEPYVRAGARLIGGCCGTTP
HHIKAMRAELDAYIESQKSASAATAQQLPAMKPEALITPKDKARPVEIKKETPKVGPELP
ALAARLANSKANPKNGDFYVSVELDPPKGAIARKILQAAETLRDAGADAINVGDSPMARV
RMSSLATCQLISTKVGIETIIHFTTRDRNLMGIQADLLGCQALGIHNVIALTGDPPALGN
YVHATAVYDVDSVGLIKIISQLNQGLDIAGNSIGTPTSLSIACALNPTHENRAQELDRFG
KKIEAGAHFAMTQPLYQLSDLTNFLDEFGECKIPILVGIMPLHSFKHAEYLHNEVPGITI
PDKVRKAMEKAGDQGASVGLELAEELLEELRPLCQGTYVVPSFGRYDDMCQFVKRIKEKS
QTKAAAKT
>A0A1L0BZY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] intermedia|TrEMBL
MKISEKLLQAHACANPPPATFSFEFFVPKTSQGVQNLYDRMDKMYDLNPIFIDITWNAGG
RSSSLTNEMVYTAQSALGLETCMHLTCTNMPVSLIDEALEKAYRSGCQNILALRGDPPLD
GSESTGDFKYAKDLIAYIHKKYGNHFNIGIAAYPEGHPEEENGDNLMKYLKEKADAGADF
IITQMFYDVDNFIRWCEQVRKAGIDIPIIPGIMPISTYSAFIRRAKWSQVVVPQHFLDTL
DPIKEDDYAVREAGTELVSEMCQKLIDSGYVNHLHFYTMNLERSTVMVLEKLKLVDSVAD
NDVVAEVLPWRKSLHPMRSKEAIRPIFWQNRKHSYISRTSGWDEQSPKRALELWGCPQSL
KDFSDIIVSYLKNEIKSLPWSDGPIGTDTNVLKDALIEVNKKGFFTLNSQPALSGIRSND
KTFGWGPKNGFVYQKQYLEFLVHKDVAQELLTKVEEHNKKDQHSVITYYAVGKQGDVETN
SKDDDINAVTWGVFQEKKFSNPLLSKSLLDEWVTIFHSKALSESVEKDKVDVFSKLFTSF
GNEFVLCNFVNNDFTSDNNVMFSLLNDLNVPYL
>A0A7K9F9Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stercorarius parasiticus|TrEMBL
MVNEAQHTCSASCSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLT
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A1Z4BSE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga endodontalis|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVESCKNNNEVKQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>Q64NU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis (strain YCH46)|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>E2XZM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens WH6|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPPARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVQALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>R0HRY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsella rubella|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFGCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIGENGLASNEAYQSDLEYLK
KKVDAGADLIVTQLFYDTDVFLRFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTK
IPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKTILAHGIKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANIFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALSDHQFSRPRARDKKLQQEWVVPLKSVKDIQEKFKELCLGNLKTSPWSELDGLQPE
TKIINEQLVKINSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLD
AVVEKCKALPSITYMAVNKGENWISNTAQSDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDYINGNIFAVFADL
>A0A100IN01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus niger|TrEMBL
MLAAMGSAVRHGAFSGGSIGGRKSCSSPPPSFTPSSFFAFHSLSSVRHRVAVSAAETALI
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDVQDPARDLPYL
IEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPQVLSKLEEVKHDDDAVKRIGVDIITDLVYGIRDLVSPGLRGFHFYTLNLEKT
VSFILERCELIPPYTEIDDSDALVDGGNLSAMDSSSYIAPNGAPIRTLASRRSSVSSIPH
NRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEEDSNGLNAETAVIQPELLTLIDKKGWWTLASQPALNGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPSKDYLNVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNPDDPDPIDIN
PANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDETK
NDVWLVCVVGQEFGAGTEAGSEEEEDEKKWMWRELANSQ
>A0A173RYJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia hydrogenotrophica|TrEMBL
MKITELFERGEFVVSAEVGPPKGIHIEHLLEEAKTYLSGITAVNVTDNQSSVMRLGSLAV
CKALKDEGLTPIFQMTCRDRNRIALQSDLLSAAMLGIENLLLLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVRKLEEGEDLGGNKLVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVRAGA
DYFQTQAVYEPEKFIKFMEKAKQFGKPVQLGIVIPKSAGMAKFMNDNVAGIHVPQEMLDE
LKKDKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAGL
>A0A519Y176|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp|TrEMBL
MKVTEHLRRAEGKTLFSFEVLPPRKGENIHTLFSNIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRKRPGTVGICAAIKNRFDVDTVPHLICGGFAKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFQPHPDGHRYACDLIGQVAELNHGRYHDHDEQYQPEGAEPVLCTDF
CIGTAGYPEKHFEAPNHGSDIRFLKDKIDRGADYIVTQMFFDNEEFFKFEKRCRAAGITV
PIIPGLKPLT
>A0A1I6GTS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yoonia tamlensis|TrEMBL
MSNTTVSFEFFPPKSLAASFRLWDCVNTLAPLDPTFVSVTYGAGGTTRKLTHEAVGTIHK
TSGLNVAAHLTCVDATKAETLEIAEGYAQEGVREIVALRGDAPKGSDGFKPHAEGFASSV
ELIAALADTGKFNIRVGAYPEKHPEAADQAADIAFLKRKIDAGATSAITQFFFEADTFFR
FRDACVKAGIDAPILPGILPIENWAGTQRFAKMCGTSIPQVVTDAFENATRDGTTDLLAT
ALATELCDNLRQGGVDHLHFYTLNRPELTRDVCHALGVAPKARVQNVA
>A0A2E0UAL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ponticaulis sp|TrEMBL
MSLQNKPKDISVSFEFFPPKSEKAEETLWESVRRLEPVNPKFVSVTYGAGGSTRDRTHRT
VKRMVDETALTPAAHLTCVSATREEVMGVVDDYLDAGVAHIVALRGDPPEGMGAKFQPHP
GGFESSVDLXAAIREHXPEYGKKFEISVGAYPEPHPDTRGYDEDLAFLKAKQDAGADRAI
TQFFFEADDYLRFVDAARAAGITMPIVPGVMLQPNFKGLCRIAGLCGAKVPDWLHELYDG
LDDDPQQRELITANVAADLTMKLADQGVKDFHFYTLNKADQALATCRLLGIKPQQKAA
>A0A822FDV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
NFGVQACLDLCCALLDSGKVNGLHFYTLNREFATIEILKKLGLWLDEQSLRALPWKKTSF
SHARSQENVRPIFWSIRPKS
>A0A0I8WPU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQYMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNQQSLG
>A0A6G2DGD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
LFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKY
EHDPESLRAAGLAYAVDQIVDLVTQDVAGVHL
>A0A4V4RYG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSILQSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARTIHQATHSLFKHYS
>A0A2S6XFS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MH60|TrEMBL
MAHSADPELSVDELVRNSSIEIVPLKGAQEKVDAVPVGTTVSVTCSPRFGLARTLDHVAA
ACRSGHRVVPHLAARMVEDRAALRDFVRGVTDLGVEELFVIGGDGEKPVGRFSEAAEILE
ELVEFDHGLSRIGVGCYPEGHPKIADDVLFEALLRKQQHADYMVSQLCFDASALAGWLRS
ARERGVTLPLRMGVAAPLQIRKLIELSVKIGVGQSLRFLSKQHGMVGNLLLGRAYEPLDL
LLAVREEISFTDLSVEGLHLFSFNQVDTTLDWLYRASGVEKAG
>K1WUF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichosporon asahii var. asahii (strain CBS 8904)|TrEMBL
MTHLTALIESQKGPVHTYEFFPPRTEQGFTNLLDRIRRLTLPPLRPPVAVSVTWGAGGST
SDRSLELADAITKMGVEVILHLTCTNMPKEKVDTALAELGITNILALRGDAPRSDEYATD
ADANMDEFQHADDLVRYIRKQYGDYFCIGVAGYPTPHPDSLDADDDLKWLKEKCDAGADY
IITQLFYDVPAFADWVQRCRQAGIAQPIIPGIMPIQSYSSFRRLINLTKCTVPDYIMQEL
EPIKTNDAAVKQYGASLATEMVKKLMASKLVPGVHFCTLNLEKSVRTILENLQWNSKKVH
DSIHSSPVSRHNQLISEEALEMDDGEEKVPLAVSAADVAQWVKNTREHTAVGGEPSWDEF
PNGRFTDVRSPAYGEIDGWGNGLKITPAQALKEWGTPATFEDLSDMFTRYLRSDPGTPTT
PFCDMPLSPESQTILDSLIALNAPDKRYWTVGSQPAVDAARSEDPVHGWGPPGGYVFQKA
YVEFFVPKSEVERLEKKLAGEKSTLFSMYAANRQGDTAGNTDKESVNAVTWAAFPGQEIV
QSTIIEELSFLAWKEEAFEIWDEWARLYPRNSPARKLIENVSDEWWLVCLIHHNYKDTEG
LWRFLLDN
>A0A2E6VEJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella sp|TrEMBL
MKVTEHLKNANGKTLFSFEILPPLKGQHIQSIFDNIDPLMEFNPPFIDVTYHREEYTYKD
VGNGLLKKQIVKKRPGTVGICAAIQNKYNVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKSETYFKPEKDGHAYASDLVSQIEDLNNGKYLDEELLNTCATNFCIGVGAY
PEKHMEAPSLDSDIHFLKKKIKNGATYIVTQMFFDNKKYFDFVDKCRKEGITVPIIPGLK
PIATKKQLNLIPHRFHVDLPEELIIEVVKCKDNAAVRQVGIEWCIEQSKELQKAGIPVLH
YYSMGKSDNIKVIASEVF
>A0A420INL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Golovinomyces cichoracearum|TrEMBL
MTMEKITDKIAALPPGSNFFSLEFFPPKTNMGLSNLRSRLDRMARALRPLFVTVTWGAGG
STAINSIDLADLCQRQLGLTTCLHLTCTNSSQELIHKTLEAARVLGIRNILALRGDPPRK
DTEIVNSEIESPAEFEWAIDLVRYIKKNYGDFFCIGVAAYPEGHADGSDPDGQSLESDLP
YLIEKVKAGADFIMTQLFFDTGAYDTFEKRLLEHESGCFKNLPIIPGLMPIQSYQMIMRT
LKLTHVKMPSDVIAYLTSIKGDDELVKKAGVEIVSKIVSHIQDSPVPPSGRRGFHFYTLN
LEKAVSFILEKTSLIRLSHSASANDNSISKFTKIESSAFPTNPNINNHTDYLEHQQSSII
SDSSNTVSNTCPLKSQPRVEAILSETNGFSNCIENCASTLAISKGGDPLGREATWDDFPN
GRWGDARSPAYGELDGYGINIHLYLNQAIRLWGYPQSTNDITSIFTNYIKGSLGAIPWSD
EPIFRETDVIKDQLLKLNEKGWWTIASQPVINGIKSNDDVFGWGPRNGFVFQKAFVELFL
SSEDLLQIQAKVKKTDMANKISWYACNSKGEFSSSETLAESTSNNRGSINAVTWGVFPGK
EIVTPTIIEEISFRAWAEEAFKIWAEWGKAYTSSSPTSPDFQKAQASHQLINRLREEVWL
VNIIHHGLIEKDGLWDLLIG
>A0A101JSB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium limicola|TrEMBL
MLVREILNSASEPVFSFEFFPPKKDEDWETLFETIANLNHLHPSYVSVTYGAGGSTRSRT
HDLVTKIQKETGLTVVSHLTCICSDREDTGSILENYLEHGITNVLALRGDKPAGIATLND
AIKDFPHAIDLIRFIRTNYPAIGIGVAGFPEGHPETPNRLKEIEYLKEKIDAGADYIVTQ
LFFDNRDYFDFVDRCRIAGITVPVIAGIMPVSTKKGMIRMSELALGARIPAPLLKQVLNA
RNDVDVAKIGIDWATAQVQELIERQVKGVHFYTLNLADATLKIFRNISRS
>A0A1F8ICH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacterales bacterium RIFOXYA1_FULL_67_7|TrEMBL
MPVSNFAGLTRMCGACGTSIPDWLKAHFDGLDDDPETRRLLAASVAAETCARLHEEGFSD
FHFYTLNRADLVYAICRVLGVREQKAAA
>A0A5E8C0U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprochaete ingens|TrEMBL
MGNDSSLKLIDKINNLERNDTFFSFEFFPPKTQQGLENLKSRVQRMGKLEPLFITVTWGA
GGSTAEKSIDLAEYIQKSGYTTCLHLTCTNMDKSLLENALKRAKSSGIRNILALRGDPPR
DGEYNTNRNSDFIHAVDLVRYIRSNYGDYFCIGVAGYPEGHVDGSDNSNQNFLKDIPYLI
EKIEAGADFIITQLFYDVEKFLAYESVLKENPLTNKIPLIPGLMPINTYQSFIRVSKLSN
VSIPSSITKIFENIKGNDEQVKLQGVKILTDIIDKIYTKTNSRVRGFHFYTLNLEKSVAL
TIENCNSIHIISPKDFSSAIDSCEEEKNEISVIQKKPRRSSTNAHNRLIVSEIRNSIDPL
NAVKASQVSSSVPSKSREFLAISTGEGSLGREANWDDFPNGRFGDSRSPAFGEIDGYGPS
LKVDNTKAYHIWGYPIDRKDISKLFISHITGTLEALPWSDQSLDRETALIQEQLINLNKN
ELWTVASQPACNAVKSDDKIFGWGPPMGRVFQKAFVEFFISPEKWETLKNKFDKDEVSQS
ISYYACRNDLKLISNTSKNSSNVVTWGVFPNREILQSTIIEGISFLSWAEEAFSLWNQWK
YIYPKTSASYILLDDISKNYYLVTVVHHEYMREEALWDLLLSLLQ
>G0AWI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella baltica BA175|TrEMBL
MAFHHAQHSQSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPGWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A0U5FWK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus calidoustus|TrEMBL
MHIKDKLAQNEAAERIGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDVTWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQERVDAALQAAYKAGCTNILALRGDPPREKEA
WEATEGGFRYAKDLVKYIKDKYGNHFCIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSDF
IVTQMFYDTDNFISWVQKCRAKGVNVPIIPGIMPIQTYAAFIRRANWTKAHIPPDWLEAL
EPVKNDDAGVREIGKRLIADMCRRLIASGIKHLHFYTMNLAKSTELVLEELKLSPTAEAP
IQRPLPWRPSLGLNRREEDVRPIFWRNRNSSYIARTQIWDEFPNGRWTDSRSPAFGELDV
YGIGIKGTNEQNIKLWGEPKSLSDLADVFVRFLEGKLDRLPWSDSPITAETNALKDPLIE
LNKRGFFTINSQPAVNGVKSAHPVYGWGPKNGFVYQKAYLELLVPAYLIDELIARIEKNE
DFTYHAVNKQGELRTNTRDSPNALTWGIFAGREVVQPTIVETVSFLAWKDEAYQLGEDWA
KCHDATSPSRKLLQGIVDSWYLVNIVNNDFHNTNDLFDLFKDLNVKDIDVEIAGEPSEPK
VHLNGATNGTTNGTASEQLAKN
>A0A2A2ETI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas salipaludis|TrEMBL
MNDLLRLATLPSDERACQALAAPRYELLPLADLQQAADALPAGAVVTVTCSPRHGLERTL
AASETLAAAGFRVVPHLAARLVRDRWHLAEAVVRLTSLGIDECFVVGGDAEAAEGDFATG
LALLEALVELPTRPNRVGVPAYPEGHPHIPAQHLQQDLEAKAWLADYVVTQLCFEAAPLL
AWREHQRQRGMSLPIHVGLPGVLSRKRLLGLATRLGLGASTRALGRQKGLVARLLRPTRY
RPDALLEALWPWLGDVAEGFAGVHLYTFNQTADTRAWCEAQCRRQCAWQSPQSSPSL
>A0A823IXK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEIFRQAGARIIGGCCGTTPDHIRALRKGLETTKPVLEKEVRPIL
ELVPEEVEDAEPGERLLDKVKERLTILVELDPPRTFDTTKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKAKIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A5P8NYT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas lithotrophica|TrEMBL
MFNTLIDKLKNSTYITLETTPGHSARFNPTIDKIAELELDKYVDGFSTTDNPLAKLKYNS
LFAAKMLQERFNKPVIATMSMRDRNKIALQSDLLAANEVDIRAILALTGDPANLSDQPHV
KGVFEGDSTLLLEMIGAFNSGMSYAGKPFAEKPKEIYPFAVINSYAKNPKTLQKKMQKKI
KHGALGIISQPVYDVESAKQLLDLIEKANNECCLEHKKAELVLGLFPITKLRTAQFLSAH
VPGINVPDEWIEKLRIASKGGESEEYKVGFELSKKLFEDLKELHPKMHLMTANQFKIAKD
ILI
>A0A8J4AUU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Volvox africanus|TrEMBL
MKIIHKINQKLKDGQTFFSFEFFPPRTEEGVENLFERLDRMATYGPIFCDITWGAGGSTA
DVTLDIATRMQNQVCVETMMHLTCTNMPVEKLESALKEIKKAGVHNILALRGDPPKGQDK
FEAVEGGFSCALDLVKYIRKEFGDLFGICVAGYPEAHPDGIVDDPEQMQKNYWGDIAYLK
QKVDAGGELIITQLFYDAEVFIKFVEDCRSVGITVPILPGIMPIMTYGGFKRMTGFCKTK
VPADILEAVEAIKDNDEAVKNFGIDLGVKMCRRLLDAGTPGVHMYTLNLERSAVAILERL
GFIDTSRVPKLLPWRHVPKGTARASESVRPVFWSHRPKAYLKRTQGWSSYPTGRWADRSA
LEYSTLSDAPQFMRRLTSTDARKEKARIAWGSSLESEEDVKAVFSKYVKGEVKLFPWSEL
EGPQHVESPAEVKVLLDLISAGYLVINNQPRLNGIPSTDSTYGWGAPGGAIYGRAYVEFF
CSPAAWVSLRPRLDAAPSVSYLAATVAGSPQGNLKHDDVVALSWGVFPGKEIVQPTVLCP
ASFATWKDEAFELWLSEWAGLYDEGSASRQLCTSIHDGWLLVCVVDNDYVDGDLAKVLLG
>A0A8J3SXD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planobispora takensis|TrEMBL
MTDHPFEIVCEVEPPTRPDLKRVRHQIGTLSQIAGSFLIPDNHIGRATVSSVAVAHEVQA
MGGRSIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTTGNRTGDLTVRSMIEEV
RGLGEDPAFAGGPAFRVGTAAGLRPLPAWKRAADFVFVQVSFSLETLLRWREANPVDVPV
YAGVMVIASENHARRMASAIPDIDIPADLVERVAADRLAGVEAACEQVLRIRDSGAFDGV
HLIPVARYREVESRLSGAL
>A0A550AC01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella eurypsychrophilus|TrEMBL
MGFHHAQHATSLNQSLAELNGDINVSFEFFPPASPEMEKILWNSVRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETDLVAAPHLTLVDASDEELKELAKHYWNTGIRDIVALRGD
LPEGSPRPTRFANDLVRLLRSVADFDISVAAYPEVHPDARNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFKQLKRFAGMTNVSIPSWLHKQFE
GLDDDPATRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGR
>A0A8I0JNF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia sp. DLF01|TrEMBL
MSFPISFEFFPTKTPEGAAKHVQVRKNLYARKPQFCSVTYGAGGSTQAGTFNMVRDIQSE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPHSDLEAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A6Q2YMP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Esox lucius|TrEMBL
MVNQVQTVDDTWRRCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESVLHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPIGTDWEEEEGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAQSYDEDLKHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKENDAAIR
NYGIEHAVGMCRMLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEKSVYEVFTSYIMAEPNQAGHKVMCLPWNDEPLAPETNLLKDELAKVN
RRGVLTINSQPSINGKPSSDSIVGWGPPGGYVFQKAYLEFFTSSENVTALLQVLKKYEPR
VNYHIVNVQGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKFSANITEILVV
AVSPGTTTFCKTFSDNPFQSHYFM
>A0A2S0VF76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium S05|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A3S3R7U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium chitinilyticum|TrEMBL
MGYSHASHLDSLNQNIADINGDINVSFEFFPPSSEQMEQTLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKEQTGLVAAPHLTCIDASRDELRTIARDYWNNGIRDIVALRGD
LPEKGVKPDMYAADLVELLRKEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNMNQAKRFALANNVKIPGWLEKQYQ
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAEAAV
>A0A3S9EGX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M4B.F.Ca.ET.058.02.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVVREFADMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKSAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGVLPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHEAEAT
GSAAA
>R5NZ57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:127|TrEMBL
MIQEKEHKGVVFSCEVFPPKRDDDIYQIYKTLDEIKTLKPDFISVTYGAGGSNSKKTATI
AAYIQNICEVEALAHMTAVGMDEASLRALLFELKKKGVENILALRGDKPRTMSQEEFDQR
YFKYATDLIPEIKKNGDFFIAGACYPEVHPESKNQEEDIQHLKQKVDLGLNCLITQMFFD
NNAFYSFMDKLEKAGIDIPVHAGIMPVTAAKQLGTSVTLSGSSVPVEMSNMIAKYGENPE
DMKKAGIEYAVNQILDLKKHGVAGVHIYSMNKADVTKQIYEASF
>A0A2T4TID0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. oral taxon 313|TrEMBL
MDNNITYIKQILNDETGEKHFSFEVLPPLKGSGTASLFRNIDQLKEFNPSFINITTHHSE
FVYHEREDGLLERQSVRRRPGTVAIAAAIQQRYGIPVIPHVICSGATKEDIEYELLDLQF
LGIENLMLLRGDKAREDRFFTPTEGGHSHTTELIEQVNSFNEGIFTDGSTMKHPGKPFVY
GVACYPEKHEEAPNLEQDLRYLKQKQDLGATFAVTQLFYDNEKFYNFVDQARKMGVTIPI
IPGIKPFAKLSQLHVVPKTFHCDIPEELAGLALLCKTDEEARLLGIEWAVRQVKDLYAHG
FNNVHFYTVSAVSSVHEVMKRIVESGLLQQNSK
>S5N2S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella bongori N268-08|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPLGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2T5PL85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas indoloxydans|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEVAAYPEMHPQARNFESDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSDSIRAFG
EQVISEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLSR
>A0A3R6X9P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OF09-36|TrEMBL
MKIRDILAKNEPTLSFEVFPPKTEDKYESVEAAASEIAKLNPAFMSVTYGAGGGTSQYTV
DIAASLKAKGVTPLAHLTCVSSTREKVHSVLDQLKAEGIENVLALRGDIPKDGKVEKDYR
YASELIAEIKASGDFCIGAACYPEGHVESVNKTEDIQHLKEKVEAGCDFVTTQMFFDNNI
LYNYLYRVREKGITVPVIAGIMPVTNVAQIKRICSMSGTYLPARFKAIVDRFGDNPAAMK
QAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNSLSEIIR
>E2NUH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catenibacterium mitsuokai (strain DSM 15897 / JCM 10609 / CIP 106738 / RCA14-39)|TrEMBL
MKIIDLLNEDKVTLSFEVFPPKTSGRYENVLKAAEKIASLNPNFMSVTYGAGGGTSAHTV
ALAKDIHEKYGVEVMAHLTCVSSTKEHVESMVEQFKENGIENIMALRGDIPSDGKVGEDY
QYACQLIKELKEKGDFCIGAACYPEGHVESPSIKEDIQHLKEKVEAGADFLTTQMFFDNN
VFYNFLYKIKEAGIDVPVVAGIMPITNAKQVSRAVQMSGTSIIPYHFKMMVDAFGDNPEI
MKQAGIIYASEQIIDLIANGVKHIHVYTMNKPDVAEGIMNNLSELLK
>A0A3R8NNS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. 602-1|TrEMBL
RVSFEFFPPKTPAMEESLWQAITRLAPLDPAFVSVTDGAGGSTRERTHRTVKRILDETTL
KPAAHLTCFGASRDGVDEVIREYWETGVRHIVSL
>A0A1V0V4I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora albolonga|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLERFSQLSNATV
PTPLKERILAVKDDPAAVRSLGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A7X8IMV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MKTSEIFKNKTVLSLEIFPPRRTASIDTIYNTLDELQGLKPDFISVTYGAGGSETNTATL
EIASAIKNNYGIESVAHLSCINLTKSEVLNMLEGFKQAGVENILALRGDVNPALAPKQDF
RYASDLVSFIKENGDFNIIAACYPEGHNECSSLVDDIRNLKTKVDAGTDQLITQMFFDNS
YFYSFRERACIAGINVPIEAGIMPVVNKKQIERMVSLCGVKLPKKFVTMMERYENNPVAM
RDAGIAYAVDQIVDLMAQDVDGIHLYTMNNPYIAQKIYAAISTLLAA
>A0A0Q2XIZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium gordonae|TrEMBL
MEFGPCGGVRPDGQCEMRSGDCVFTDIVRWSGPAPVAGRETGPAPLVLTDFSCAPFDRDD
VAATAAVLAPSCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDRNRIVLEQEL
RGLRTIGVDTVLCVTGDGRGYDVRPDVTQTFDLDGLRLVSLAASLGVLPAVPETPTAPPV
AARPARLVEKERAGAGLAVLNHVPFPDMIAEFMKTARAQGLSIPVIAAVAVFTDSVSAAV
LQGLPGLELDPAVTESVLSSADPIAAGISAAVSEARSLLSIDGVEGVNVSGLASASGARV
GAEIKAEVGRLIREGVS
>K2Q8W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium albertimagni AOL15|TrEMBL
MTKPERPIAKTPHARISFEFFPPKSPDMEDQLWQTVKALQPYQPDFVSVTYGAGGTTREP
TLATVKRLIADTSLATASHLTCVGATRDEVRAVVEEFQAAGVRHFVALRGDPQGGMGSRY
APHPGGFVNAADLVSGLRDLGDFEISVSAYPERHPESENDDVDLDMLKQKVDAGATRALT
QFFFDNDIFERYLERVRAAGITIPIVPGIMPIQNLTQLKRFASMCGASTPSFLDERFEGT
EGDAQARAAVAADIAAEQIADLSRRGIEEFHIYTMNRAPLTIATLERLGIAAKVGEVSNA
AA
>A0A7W4T7S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas umsongensis|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKNDLRGLLTQYKAAGIQRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEIAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQSFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A7X0W5X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria welshimeri|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELITLGADVVGINCRLGPYHMARALETVPLYDKAYLAVYPNASLPEMQD
GKVIYQSDTDYFAHYGEVFRQEGARIIGGCCGTTPDHIRALRQGLQTTKPILEKEVRPIL
ELVPEEVVDEEAGERLLDKVKERLTILVELDPPRTFDTTKFFEGAEALNNAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTEEVRERMREAEEHGYANEEGMAIARELIDAICAHFQGIYIITPFLRYDLSV
ELAKYIQKKQQVEIISK
>A0A435VXH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.001.02.1.1|TrEMBL
GYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRAITQFFFD
NDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFEGLDKDPQ
THALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAAGSAAA
>A0A2N3PQ00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Telmatospirillum siberiense|TrEMBL
MAVSSASDPSDTQIPVAQPAPHLAVSFEFFPPKTEKMQDALWECVTRLAPLSPSFVSVTY
GAGGSTRERTHDTVTRIARETGLKPAAHLTCVGATRAEVDEVAGRYWDAGIRHIVALRGD
PPEGQGEYRPHPDGYAYALDLVKGLKRLADFEISVAAYPETHPQATSPEADLDNLKRKVD
AGASRAISQVFFDVDLFFRFRDRATAAGIAVPIVPGILPVTNFAQAQKFSAACGASMPAW
MSELFDGLDDDPDTRRLVAATVAAEQCRALVAGGIDELHFYTLNRADLTYAICHILGVRA
AKSV
>A0A1Z8Q5F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED36|TrEMBL
MSENYQKLRDVLQSGRFAITAEIPAPVSASSYEMEEKIKILKGSVHAINVTDNPGATAHM
SSLAGSTIVRNQEIDPILQITCRDRNRLAIQSELMGASALGIDNVLTLAGDPVKNGDQKD
AKAVFDINSKTILSIMDGMNNEGKTMSGKELQSKSNFFPGGAAILHEPEDNWDPKALNEK
ASFGAMFIQTQFCYDVELVKKYMQRIVETGLSEKLYFIIGIGPLRSDKSAKWMRDKLFGT
VMPDSIVKRMESAGDQIQEGINICAELIQSFQEIEGVHGAHLMAPRNLSAIPETVKRSGI
TI
>A0A257Y2G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium 12-61-10|TrEMBL
MNQRTFSFEFFPPKTAEGAEKLRATRAQLAQLNPKFFSVTFGAGGSTRDRTLETVREIQA
SGSDAAPHLSCIGSTQDNIREILNEYKSQGIRHLVALRGDLPSGSMDAGEFNYANELVSF
IRSETGDWFEIEVAAYPEIHPQARSWTDDLANFKRKVDAGANAAITQYFFNADAYFRFVD
EARAMGVSIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLASIRAFGLDV
ITDQCERLLACGAPGLHFYTMNQAGPTTTIWQRLGLS
>A0A370B8T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces corynorhini|TrEMBL
MALGTASTRSDHARTVRDLLASGKTSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVRATERIAADTTLTPVAHLTAVGQSVAELRNMVGRYADVGIRNILAVR
GDPPGDPMGEWVDHPEGVRYAAELVGLIKEAGDFCVGVAAFPEMHPRSADWESDTRHFVD
KCRAGADYAITQMFFDPEGYLRLRDRVAAAGCATPIIPEIMPVTSIKMLERLPRLSTAVF
PPELKERILSVKEDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYENLG
LHEQS
>A0A381L8B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blumeria graminis f. sp. tritici 96224|TrEMBL
MHIKDKLREAERSGHPTFSFEFFPPKTTQGVQNLYDRMDRMHGLGPSFIDITWGAGGNIA
QLTVEMVSVAQSQYGLETCMHLTCTDMGLEKVDKALKDAYQAGCTNILALRGDPPREQEK
WTATDGGFHYAKDLVKHIRATYGDHFDIGVAGYPEGCDDQDDPELLLDHLKEKVEAGGTF
IVTQMFYDVENFLEWVGKVRAKGINVPIIPGIMPINTYASFLRRCNHMGCKIPPKWATAL
EGIKNDDSAVRSIGTGLVAEMCRRILASGLIHHLHFYTMNLAQATRMVLDQLGLTPSEER
PLKQALPWRQSLSLGRRDEDVRPIFWKNRNKSYVTRTQDWDEFPNGRWGDSRSPAFGELD
AYGIGLKGSNQQNRKLWGEPECIQDVAEIFVKYLDGKIESLPWSEAPISSEANKIKKELE
DLNRRGFLTINSQPAINGIKSSDSTYGWGPPNGYVYQKAYLELLVPAYLIDELLTRVSKD
AYLTYYAVNKAGDLKTNSTHEGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGID
WAQCHSATSPSRRLIEKIMDTWYLVNIVNNDIFENNKLFELFEGLQVNDIDKPLESPKIM
NGNSVHQNGHEPHVNGKVTIENGNH
>A0A5J6VPL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus sp. 'AMD consortium'|TrEMBL
MAHSVEFFPPKNAAGEERLREAITALLPLDPEYASVTFGAGGSTRERTFATVTMIRQDYD
LEAVPHLSCIGSTEAGIREILEDYRKQGIRRIVALRGDLPEGMENPGHFQHAADLVAFIR
HFGGFEVYVAGYPDIHPRATSARNDVMHLAAKVRAGADAIITQYFFNPDAYLQLRDELQR
EGVEVPLVVGVMPITNFEQISRFSAMCGADIPQYLRRRMDAYAADPQSQYQLGIELLSRQ
CQLLLREGAPSLHFYTLNQAEATAAIWRNLGF
>I3YEM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiocystis violascens (strain ATCC 17096 / DSM 198 / 6111)|TrEMBL
MLFQNDSTPLYSVELFPPKTAEGMDKLKLEIAKLNALGPAYFSVTYGAGGSTREGTLETV
SWLRGLGIETAPHLACIGSTREQVRELLNHYRQQGIRRLVALRGDMPSGMGAGNQGDFRY
ANELVTFVRAEFGDAFHIEVAAYPEYHPQSGSPARDLENFKRKVEAGADGAITQYFYSAD
AYFAFVASCRKAGVEIPIIPGIMPITNYTQLARFSDTCGAEIPRWVRRRLEGYGDDVESI
RAFGHEVVLTLCRHLIEGGAPGLHFYTMNQSGPTTRLWNDLELAIVH
>A0A5N4FKB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium damselae subsp. damselae|TrEMBL
MQPITNYQALSLQDSELRVRYNDVTRGVYFIGTTPPKTSTNLSDVDGIADKLVDRIKDLA
FDGLIVYDIQDEGSRISKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSEPEVFN
QWLNEAWEQYQVRDIVLVGSPSTQNQVSLPLHEAYKTIADNEHPFFTGGIMIAERHAKKG
NEHQRLIEKYQQGCNFFISQAIYDTQATIDLLTRYAIECQEKGLKPQRIILTFSPCGSAK
TLEFIEWLGVSVPEATSLRILNADNPLHESIKMCCNSLNQILEAVVEYDLPLGLNIESLT
NRKEEIEGSILLYKLLRSTMDMYLAQHEFRKQQGLKKAF
>A0A2R5GKV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hondaea fermentalgiana|TrEMBL
MPVIGAELTDFARALAESGVTEVLALAGDGPERSPACYDASHVLETLLDEPGAQGALECI
GVAAYPTGHAIAEDSQLWQALERKADLLSTRKPASQIFVATQLGLSTSALVDWHENLRVK
VPFLANAELCVGVFGLVPASRTRTLARRLGFGKGLVGLMDSLPSDSLMSRASAEMLRSAA
LPEAVSLHISTFDTRVLAADTFWAERLQDYAQHGRD
>A0A2G5XDY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. P17b|TrEMBL
MSLLEKLQTNVLTADGAMGTILYSYGIDYCYEELNIEKPEIIEQIHQDYIAAGADIIQTN
TYSANAIKLARYGLESHVTEFNKAAIQIAKRAAAPGGQFVLGTIGGLRGIRKSDATLDEI
EKVVLEQANALLTGDPDGLLLETYYDFEELASVVSTLKKVTDVPLIAQVSMHDPGVLQNG
LSLNDALHQLESLGADVVGVNCRLGPYHTIQAFDNVTLPKKAFLSAYPNASLLDVEDGRI
VYESEAEYFGRAAVLLRDQGVRLIGGCCGTTPKHIKAAKTQLARLAPITEKVVQPSKPIV
IQEASPVQHQPLHIKAKTERTVIVELDTPRHLETEDYVKGANVLYDAGVDAITMADNSLA
SPRISNMAMGSIIKMQHNIRPLVHLTCRDHNLIGLQSHLMGLDALGITDVLAVTGDPTKV
GDFPGATSVYDVNSMELIQLIKKLNEGISFSGKPLRKKANFSISAAFNPNVRVVERAVQR
LDKKIEAGADYFITQPVYTKEKIIEVYEATKHLDTPIFIGIMPLTNIRNAEFLHHEVPGI
KLSDEVLERMRQCSDDRDQSTEVGLEIAKELLDTAAKYFKGIYLITPFLRYDMTLELYEY
IKELDEQKERELLHAETSY
>X1HLP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
ELKGSPKFVTGCSIKPAKNEIALEAELELAQKKVREGTQFIVTPPVFNIPAFTYFMEKAK
ALGVPVIATVFLLKSVGVAKYIATNVPGPPIPEEMISRLRKAPDRINECITIAGELINTL
KEICQGVQIVTMGWENRLPAILDAAKI
>A0A7Y3TXR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas azerica|TrEMBL
MSRQEHPLGISFEFFPPNTDAGREKLMRTRDQLAAYQPRFFSVTYGAGGSTQVRTRNAVR
EISQSGITTAPHLSCIGSDKAQLRDLLAEYREEGVDSLVALRGDMPSGTASMGELRYANE
LVEFIREETGDHFEIAVGAYPESHPEAPSLDKDVENFARKMKAGANIAITQYFFTADAYF
NFVDKARALGVTQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYADDSEAIADF
GNEVVTRLCERLLDGGAPGLHFYTLNQSAPVLKIVDNLTG
>A0A8H4QR77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrocybe pediades|TrEMBL
MKLSTQIEARDADHPFFTFEFFPPRTDQGFENLMSRISRLSALNPIAISVTWGAGGSTKD
RSLELASLTQQSGLDTILHLTCTNMERGLIDEVLKTAKEQGIQNILALRGDPPRGKEEWI
PADPRFTRAIDLVSYIRSVPEYSDWFCVGVAGYPDGHPDTTTDEDTEISRLKQKVDAGAD
FIVTQLFYDADYFISWYKKVREQGSPFDSVKPFFLIPLRRYNGTRNSWSHADTNIFLHDD
SLVKDYGVKLAVAVIQEVQSGTGINGFHFCTLNLEKSVQRVLQTLGWAGSSSTAPNKLIA
DSVPGDLASSSTPVQGDLVISPQSATDSATLGLSSILTTTVEAGSGELNKAATWDDFPNG
RFGDFKSPAYGDQDQWGGSNFSKNEALIESGKPKTVEDLTNIFLDHLHSKLSSTPFSSGP
LSAESLTILPHLERLNKRGWWTVGSQPAVNGASSSDEVVGWGPRSGYVFQKCFVEFFCGE
KDVEVIEKKIIESGNGWVHYFAGNYKGECRTNVPEGGRNAVTWGVFPGQEIVQTTIIERE
SFLHWKDEAFSIWSEWASYYRPDSDERKLLEDVRDNRWLVSIVHHDYLDPEALWTFLLDQ
>X1FBU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
DKKKDLEHLKIKVDNGADYIVTQLFFDIDVFLEFVENAKRIGIDIPIVPGVMPMDKYGPI
KFVSKQMGIEIPEKLKDKLEAHKDDKDAIKKILEEHTLLMCKKLVEQGSPGIQFYTMDKP
EGTKKVLQELCKE
>I3DVD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus methanolicus PB1|TrEMBL
MSFLNKLENQILIADGAMGTLLYSYGTDCCFEELNLSQAEQITNIHRAYIDAGADVIQTN
TYAANYLKLKRYGLEDFVKEINSAAVRNAKKAAQNRAYILGTIGGNRGIKPNSIPIEEIK
RSFREQLYCLLLEGVDGILLETYYDLEELKTVLQIARKETDLPIIAQVSLQEVGIMQDRT
PITEAFNRLEDIGADVIGLNCRLGPHHMLVTLEEVPLPKSAFLSAYPNASLPAYTDGKFH
YEGDADYFKKSARSFREQGVRLLGGCCGTTPEHIRAFAAELHDAPPVTEKAVKQKPKKII
IQPEEAKREYPPLQDIVKERKSIIVELDPPKKLDATKFFQGAKALKETCIDAITLADNSL
ASPRISNSALGYLTKTQIGLRSIIHITCRDRNIIGLQSHLMGLHTLGLHDILAVTGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNEGLSISGKDLGQKAAFSVAAAFNPNVRSLEKAVS
RLEKKMKFGADYFISQPIFSEEKLIEVYEATKHINAPIYVGIMPLISSKNAEFLHHEVPG
IKITDTIRDRMAKFKDDPQQAALEGLNISKSLIDAALDLFNGIYLITPFLRYELTVELAE
YARSQSENLVRRNNYVQSIFH
>A0A847ECI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp|TrEMBL
MSFSFEFFPPKSDQGCLRLFDNIKELAALKPAYVSVTYGAGGSTRNLTHDLIMRIQKETG
ITVVSHLTCVGSTSEEIHHILENYRKCGIENIMALRGDPPAGSEKFVAADGGFSHANELV
SFIKTHFPEMGIGVAGYPEGHAETPNRIIEMDNLKRKVDSGADYICTQLFFDNRDFYDFR
ERCEIAGIDVPIIAGIMPVTSIKGMYRMAELSLGTRFPAKLQRALQRAEDDSYVEKVGIH
WATQQVLDLIDNGTKGIHFYTLNQSKATREIYSSLGISSSQSLNR
>A0A0F9QDK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MNFFDALRTKRFLITADVVPPKGVNISKMLSRIDSLVSKVDAMNVVDLPGSVMRVSPLPI
ALLLKERGLEPILQMTCRDRNRLALQADLLGAYILGITNILALTGDEIDLSDDPGVKPVF
DLDSIELLKAARKLEKGHDLGGNPLRGSPKFCIGAVVDPGADPVEPEIEKMQRKVEAGAE
FFQTQPIFDIKVFAEFLEKAGKAEAPILGGVLL
>X0ZZS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
QQKLGVETIIHYTTRDRNLIAIHSDLVGGHVLGVRNILCLRGDPPALGGHTDVVAVWDVG
SVQLIRILKMLNDGVDWTGKSVGPSASFFIGGSANPNTDETKAELNLMRRKAEAGAHFFM
TQVIYDPDRLERFLERTTKFKLPIIVGILPILSQRQAEFLHHRAPGITLPEDALERLRRA
GEDGVAAEGLAIARDILAVAKAKAAGVYIVPSFGRYEPLVELVAEAKR
>X1PLT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
ITAGARFFQTQAIYDFDAFARFMKRAEGFNIPILAGIIPLKSAGMARFMNKNVAGVFVPE
ELIDKMAKTEDKARTGIDIAANLIKELKGMCQGVHIMAIGWEKRIPAILDAAGL
>X1F2U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
SAFLTGQFSEPNFFPGAVVNPGADTEAAFELQLIKMEKKIEVGAKFFQTQAIFNVDTFAK
FMKRVEGFNIPILAGIIPLKSAGMARFMNKNVAGVSVPEELIDQMAKTEDKVRSGIEIAA
NIIKELKGMCQGVHIMPIGWEKKVPAILDAAGL
>X1HX02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MAKRPAYSNLVKTMREGKFLFTGELEPKKMVDLSSILHSAEEMKKTGKIVAANVTDGPQG
DAYTCSMVPCYLVQEKVGLEAIWQMTVRDRNRIALFGDILGGAILGLKNMLALTGDHSAL
GDHQNARAVYDLDSTQLIDLVSKMVDDGTDLEGKEIEGGKIEMNVGCAANPNSNPREPEI
LKVGRKVEVGADFIQTQTSFDIDDAKEFLKELEKFNIPVLLGLFPIKNYGIAWYFNE
>A0A4R8XKJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TmT2-48-2|TrEMBL
MPDTSDPACGNIPFSFELYPPKSDAATSALHATIERLAAAGPEFISVTYGASGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSSAEASQLIREFLDAGVRSFLALRGDPPEGAREGEAF
LGDLGSAAELVQLIHRVQAERVPYREAVIPGLPAARTIKREREKVRIAVAAFPNGHPQSR
SAAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRQATELARELVAGGAPGLHLYAFNQHE
TVLAVLDGAGLLAPTPSAT
>A0A2W6Y8W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp|TrEMBL
MSPDIDPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERASVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDQSKFLSGRKLTSPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PLASAKTAKWIRSNVPGIHIPDAVIKRLEGAEDQKKEGKQLCIDIINEVKEIEGISGVHV
MAYRQEEYVAEIVHESGVLKGRKPWQREPSPVDALVAERLEAIRGEKLEDQQQLAEKAAS
HPH
>A0A3C1KQL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haliea salexigens|TrEMBL
MPTISFEYFPPKTADGKTALLERTTPALQALDPGFFSVTYGAGGSTRDSTFGIVSALCER
GIDVAPHLSFGGDDENAISDLLQRYRDMGVRRLVALRGDMPSGMGGANQLVYASELVSFI
REHSGDHFHIEVAAYPEIHPQAESYNSDLQFLKEKLDAGANSAITQYFYNVESYFYFLDQ
CAAIGIDKPIVAGIMPITNFANLARFSRNCGAEIPRWICQRIEGYGNDQESVRQFGIEVV
TQLCQTLLENGAPGLHFYTMNQVEPTRQIRNNLGL
>A0A315T6M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CC120222-01a|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKDELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQARNFEADLGNFVHKVKAGADSAITQYFFNADSYFY
FVERVQKMGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITHMCEQLLQGGAPGLHFYTLNQAEASLAIWNNLKLPR
>G2Y122|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryotinia fuckeliana (strain T4)|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRALDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDGFEQKLRDHPSGAFKDIPIIPGMMPIQSYQMI
KRTTKLSHAKLPSTIITRLDAVRGDDEMVKKVGVDILSEMVEHLKSTKSQYSGPRGFHFY
TLNLEKAVSFILERTELIPDAETVAALEPEYVPTIPDIADLLSIHSGSHKRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGPKNGFVFQKAFVELFI
PVADWKTLHAKLTSPDLCDTVSFYASNAKGDFISSDEAVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSQTRKIIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLS
>A0A417XZP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides immobilis|TrEMBL
MTTEGRAPRLTRTRADVVRRLLANARFEVLPTARVEDAVATHLPPGRTVTVTASPSKGLE
ATLALTERLTARGYDVVPHLAARMITGRSELVEIADRLRASGVTTVFVPAGDADPVGSYA
GALDLLDDLVAIGSPFPQVGITGYPESHPTIHDDVTVQTMWDKRQHATQIVSNLTFDPRV
LTSWVRRVRARGVTTPILVGLPGPVDRTKLLSMATKIGVGESTKFLAKNRGVFARIAVPG
GYDPLRLLNRAAGVLGDEQMNVCGLHLFTFNQVAETEAWRRAQLARWER
>A0A7Z9TSM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lambdaproteobacteria bacterium|TrEMBL
MHLIELYQKQDFVYSIEIFPPKTEKGMEKLKITLEAFRSSAPDYFSVTYGAGGTSRENTH
ELSAYIQHELDVPAMAHLTCVSHTAKEIDDVLTKLKNSKIENMMALRGDPTAGTERFIQP
KGGYRYAVELITAIREHSDFGIGAAGYPEGHVENPDIDNDRKHLHEKIAAGAEFIVTQFF
LENTHFLRWRDKLHHEGANVPLVAGILPPSNWKATKRMSEMCCVNIPQDLSESLIKYENE
PQTSREIGFEHVEQQIDELLAEGVEGVHLYALNSLETVKRLGPKLRDAASTSSSLPAD
>A0A836QF62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lambdaproteobacteria bacterium|TrEMBL
MHLIELYKKKDFVFSIEIFPPKTAKGMEKLKTTLEAFKSCTPDYFSVTYGAGGTSRENTH
ELAAHIHHDLDVPAMAHLTCVAHTVEEIDVVLSNLKNSEITNVMALRGDPTAGTKHFVQP
KGGYHYASELITAIREHSDFGIGAAGYPEGHVENPDKDDDRKHLHEKIAAGAEFIVAQFF
LDNTHFLRWRDQLRREGASVPLVAGILPPANWKATKHMSEMCGVSIPEDLAQALIKNETD
PEASREIGFDHVENQFEELLQEGVEGVHLYALNRLSTVERLGPILKDASGTISTPHL
>A0A8E2BKX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter phosphatis|TrEMBL
MTQHKRTFSLELFPPQTPEGAEKLRAARARMAALKPRFFSVTFGAGGSTRDRTLETVLDI
QGEGHQAAPHLSCIGSTRESIRSILEQYRANGIRHLVALRGDLPSGMARPGTFRYANELV
EFIRAETGDWFHIEVAAYPEYHPQAKSPRDDLVNFKRKLDAGANSAITQYFYNFDAYAHF
IDDCQAIGIDVPIVPGIMPIASYSSLARFSDTCGAEIPRWIRKKLESYGDDSASIRAFGL
DVVSGLCQQLLANDAPGLHFYTLNQDALTTQLWQRLHLS
>A0A6I4YRJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharibacter sp. 17.LH.SD|TrEMBL
MPEISFEFFPAKTEDGAVSLLKTAQTLAEFDPRFMSVTYGAGGSTQGRTLATLCDMAKCV
SVPLAGHLTCVGASKGEVDDVARSFWDAGIRHIVALRGDPRPVDGKAQRFEPHPQGYRNA
AELVSGLKKIAPFEISVAAYPETHPEALSPEADLDNLKRKFDAGADRAITQFFFDADIFL
RFRDRLSAAHITKPVIPGILPLSSAVQAWKFAAMCGASIPEELRVLYGDLDKSPAVRARI
SAILADRLCQKLVAEEVGHFHFYTLNQAVPCSALSLLLRHGKVPSSLE
>A0A349UMC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
SFQTEPSRTAGGKSTVACACGEGRFDFVSPGAIDRLSDKKEPPLTKSRDILKAMADAPQV
FDGAMGTEIYRRGVFLNACYDELCLTNAQLIANIHTDYVDAGADVIETNSFGANRVKLRA
FGLAEKAVEINAAAARLARAAAGETVCVVGSVGPCLANPQPLDETLRLELQSAFDDQVRA
LVAGGVDAILLETFTGLAELQLAAEVAARYGLPVLASVAVDEEGRSAGGTSAALLAETLD
ADGHVSAVGLNCGCGPAGILKPLADVIARTRKPVIVMPNAGGPREVGGRKLYLNSPEYFT
EYAKKYVELGARGVGGCCGTGPEHIRLAARAIRTLSGVKKHVEVRAREAARDVAVVATAE
KSALARALAAGKKVASVEFLPPRTGAGMGKLLAKVRQVQAAGVEAVNIPDGPRASARVSP
MITALTIERETGVEVILHCCCRDRNLIGMQSDLLGAAAAGLRNVLLVTGDPPKLGDYPDA
TGVFDVDSIGLTQLVSNLNHGFDAAGHPIDPPTALLAGVGANPCAVEMQREIDRYFAKLD
AGAEFVITQPVFDPQALLRFLDRVEKHPRTVPVLAGVWPLLSFRNAEFMNNEVPGVVVPP
AVLDRMAACRTGDDAKKTGVDIAREIMAAIAPRVQGFQVSAPLGNVEMALTVLAG
>A0A7C3T6B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MGSKGRLLELLDSGVVLGDGAMGTMLYSRGVFLNRCFEQLNIDSPDLVRQVHKGYIEAGV
DFIETNTFGANRLRLSRYGLAAEVEAINSSAVRIAREVAGDSVMVAGAMGPLGVQVDMRD
PQARVQAMDVFSQQARCLAEAGVDFLILETFSDVDEILVAVEAAVQTGLPIVAQMTVDED
HRTAYGVRADRALARIAAHEGVVAVGLNCSTGPASMLACLELVLKAVDKPISVQPNAGMP
RQVEGRMLYMSTPEYMAEYAKRFYQLGARIIGGCCGTTPEHIRQVVCAVRSMHKASAAAS
MPVVTVRPSPAEGPGTAVQPFAQRSRWAARLAAGQKVETVELTAPRGTDLGPLIQKARLC
AETGVDAVNIPDGPRASCRLSPMVTAMQIQQQVGIEAILHVCCRDRNLIGVQSDILGASA
IGIRNLLIITGDPPKLGEYPHATGVFDLDSISLTRLVSRLNRGIDLGGNTFSPPTSMVIG
VGANPTAISLDKEVSRFRQKIDAGAEYAITQPVFDPGSLFRFLERVGDCRIPIVAGIWPL
TSLKNAEFMANEVPGVYVPKWILDRMARAGTKAEGIRLGCQIAMEMIEQISDAVQGLAVS
APFGNVRIALAVLGKIGIDQIG
>A0A7L9Q694|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia solanacearum|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILDTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRKEMNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLEGFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>A0A7V1Q1E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
PLTSLSGMRRMAQLALGTHFPARLLRALDRTDGTPESIRRVGVHWATEQCVDLLDHGVDG
IHFYTLNQSTATREIYATLGVQSSSQLSS
>A0A7X0UHA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia solanacearum|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRGILDTYRANGIRRLVALRGDLPSGMGEIGEFRFANELVEF
IRKEMNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAGATRAIWQRLGL
>A0A0E2B213|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira kirschneri str. H1|TrEMBL
MKKVSEIYGSTKGPVYSFEFFPPKTPEGDLKLMETVKELSLLNPDFITVTYGAGGSTRDK
TAQILSRISKNYSFPTVSHFTCVGSDKGQILETLKGIRSSGIVNLMALRGDPPKGEGEFK
KVENGFENATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVRNLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A4U1YFR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio genomosp. F6|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELINIADDYWNNGIKNIVALRGD
IPAGGGAPDMYASDLVKLLKSQHDFDISVAAFPEVHPEAKSAQADLINLKRKVDAGADRA
ITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQASRFAAMNNVKVPGWMAQQFN
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPA
>A0A1U7LUJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neolecta irregularis (strain DAH-3)|TrEMBL
MKLTKALNEWQGPFYSYEFFPPKTDAGMANLHSRISRMSRFNPLFVSVTWGAGGSTAQST
FELAAACQNEYGLTTMLHLTCTNMNQIVLDDTLEKAKAAGIRNILALRGDPPRTTEYWAD
SPTEYQYAIDLVRHIRRKYDDWFCIAVAGYPEGHSEGSSPRYQDPKIDLPYLIEKVRAGA
DLIITQLFYDTQKFIDYEKVLREHESGLFELIPIIPAIMPIQSYQSFRRLTKLTHAEVPP
SLLKKLESVKRDDQTIKEMGVEVAVSMIQAIQTQTKGRCRGFHFCTLNLERNVAFVIEKS
GLLESVQKYRERSSFAIDDSAFTTSNISKNSRRTTSLISNPHTRIIVEEICQGLHNIDLV
TSTTDAATLADIETPASVALSVSEGEGAMGRQATWDEYTNGRFGDARSPAFGEIDGYGVS
LHIPSQQALQFWGHPATVNDISNVFCSYLRQDISAIPWSELELNPETSTIRDHLLRLNER
GWWTLSSQPAISGVPSDDPIFGWGPCGGWVYQKA
>A0A085HCC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leminorella grimontii ATCC 33999 = DSM 5078|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPSTPEMEQTLWQSIDRLKTLKPKFVSVTY
GANSGERDRTHGIIKGIKEKTGLTAAPHLTCIDATREQLLDIAKDYWNSGIRHIVALRGD
LPPGGGQPEMYAADLVELLRGVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFAKMTNVRVPQWMSQVFD
GLDDDLETRKLVGASIAMDMVKILCREGVKDFHFYTLNRAELSYAICHTLGVRPV
>L8J6Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium marinum|TrEMBL
MGYSHASHIDVLNQNLADINGDINVSFEFFPPSSEAMEKTLWNSIHRLKTLQPKFVSVTY
GANSGERDRTHSIIKDIKEQTGLVAAPHLTCIDATRDELRAIARDYWNNGIRDIVALRGD
LPEKGVKPDMYAVDLVELLRKEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGACRA
ITQFFFDIESYLRFRDRCVATGIDVEIVPGILPVSNMKQAKRFALANNVKIPGWLEKQYE
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAQAEAQ
>A0A1I6J7W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] aminophilum|TrEMBL
MKIIDILNKKKTTLSFEVFPPKKIENFDSVQQVTEEVAALKPSFMSVTYGAGGGTSEFTL
NIAGNIRAKYGVEVVPHLTCVSSTKEDVHRMLQKIRDHGFDNIMALRGDIPKDGAPHNDY
HYASELIEDIRAHGNFCIGAACYPEGHVECAHKDEDIRNLKRKVDAGVDFLTTQMFFDNA
EFFNFLYRLRENDIRVPVLAGIMPITNAVQLSRSVALSGTSVPTRFREIVDKFGDHPAAM
KQAGIIYATEQIVDLIANDVRHIHVYSMNKPDIHVYSMNKPDIAEAIQKNLSEILKI
>A0A117LEL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium 62_21|TrEMBL
MFIKEFYASGRPVVSFEVFPPKSPNAVRVITDTVAGLQKLNPAFISVTYGAGGSTREGTI
QIASVIKNRFRIEALAHLTCVGHTVAEINVILDRLQAEGIENILALRGDPPADARDFDYS
ACDFRYAVDLVRHIRTRAGVCIGAAAYPEGHISSPRLSTDLAYLKEKVDAGVDFLITQLF
FDNRVFYNFLENARRIGITCPIAAGILPVLNAGQIKRIVSLCGASIPAKLWLMVDRYADS
PEDLQKAGVEYASAQIEDLIANGVEGVHLYTLNKVEPAAEILRNAGLVGEETCLR
>A0A3C0EPH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHINDIFDEQPTTLSFEFFPPKNEKSAESLYQAIEQLTELKPSFVSVTYGAGGSTRELTH
DLVVRIQQQSQLNPIPHLTCVCHQEPEIASILERYAAAGVGNILALGGDLPADKPGYDTK
QDAFEHATDLVSYIKQFGEKGNHPDKRGFGIGVAGFPEGHPATPNRLLEMDYLKAKVDAG
ADYICTQLFFDNRDFFDFCERCELAGINIPIIAGIMPVSTVTGMKRMAELSAGSRFPAPL
IRAIQRVQDDPDAVKQVGIHWATKQCMDLLDNDVRGIHFYTLNKSDTTQQIYLRMGLNDS
TPVTGK
>A0A517SH49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulifigura coniformis|TrEMBL
MTVLRQILENKPFCLSIEIFPPKSADADSALWENLERLMPYGPSFVSCTYGAGGSTRNRT
VELCREIRTRFNVPATAHFTCVGSTIPELTDWLDVAAEAGIQNFMALRGDPPRGQEGFKP
VDGGLSYANELVGLIRKTKPQSGIGVAGYPEKHPEAPDHDVDLSNLKRKVDAGADAVFTQ
LFFDNASFLRFRDRCRAAGITIPIIPGIMPITEFARIKRITQMCGAAFPEALAARLEAVQ
DDLDAQFKIGVEFAIEQCRELCREGAQGIHFYALNRSSACEQILDALDQPGAARKPA
>A0A1E4ZN66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MTALADKIKDKQFAITAEIVPPVSASGEKLLAEAEHLRGLVDAINVTDGAGATTTMSSFA
ASALLAGGGFEPVLQVTCRDRNRIALTADLLGAAAQGSYNLLVLMGDDPAKGDQPEAKPV
FDLDSRKVMQLARQLRDEAVLPSGKAVSPAPQFFIGAADMPIDPPADWKPEALQSKIECG
AQFTQTQFCFEPEVARRFIGRLTDAGVTEQVGVLLGIGPIISAKSARWMNENLYGVTVPD
AIIARLEGASDAKAEGRLICAELIQQYREIPGLAGVHIMAPAQKPDAIADAINLAG
>A0A143G531|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. TGL-Y2|TrEMBL
MTKRVPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSAIHDFN
GKGTPVAPHLSCIGDDKARIAELLDFYKSQGIDRIVALRGDLPSGQVGLGELAYASDLVA
FIRQHSGDHFHIEVAAYPEMHPQADSFNKDIQNFVTKAKAGANAAITQFFFNPDAYFYFV
DRIQKEGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHIEPNRQLVLDLGLA
>A0A3E2CTG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium NR017|TrEMBL
SLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRFRDLARAAGINVPIEAGVMPVANASQV
KRMTSLCASRITSQVSAMMDRWGSNADCLRDAGSIFASQQINDLIAEGVDGIHLYTMNHP
GIARRIWANVKPLFTKIG
>A0A7X4Z8B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKISEILKQREVTISCELFPPKKGSELKKAHEVVRETAKLKPAYISVTYGASGGISEHTV
DMANEVQNRNGITALAHLTCASSGKEKVRQVLGELKEKRIENILALRGDIPENLDFPLPG
QYHHASELIEEIRAFGDFCIGGACYPEGHPEAESIDADLDNLKRKVESGCEFLTTQMFFD
NNILYNFLYRALKKNIQVPVIAGIMPVTNANQIKRIISLSGTILPQRFRAIVERFAENPS
ALKQAGIAYATDQIIDLIANGVNHVHIYTMNKPDVAGAILSNLSEIYHAGQPEGAF
>A0A3B9CHY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MGNTKHTKEQIRERIQQKKLLFDGAFGTYYGGKYDTKQLPELANLEAPERVKEIHTEYLE
AGAQILRTNTFAANSFCMDMSKEQIEETLRSGVRLAREAVAAWRERTGETKEVYIAGDIG
QIPCDALAQKDTLCREYEEICRIFLEEGVDFFVFETFSEMEEILPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGAIKEIDAVGFNCGVGPSHMYRILQTLYKPADKFLTALP
NAGYPQMVTGRMIFTMDNREYFVDRMQQMIALGVDMAGGCCGTTPEYIADLAGNLDFTQY
PQTQEKAEPEKKQAGTEDHSFYHKKEAEGRKKLIAVELAPPMGIDDEKLMDAAHLLQRSG
VDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINSIH
NFLVITGDPIPSLVRTTVKSVFNFDSVGLMQILADMNEEQFAQAPVSYGGAINQGRRNLE
VEIGRVKKKMAAGATFFLTQPISTKESADRVRRIKEETGARILCGIMPFVSLKNATFMKN
EMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVIAMTEDFADGYYFSFPFNRVTMLEK
ILD
>A0A7J4DRA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrodictiaceae archaeon|TrEMBL
SVVQIHHPLPMRAPPPHFYNGLTCQKHHSNLQAIHMRTKRKFKASGYVVCWCVKLVEVWV
ELEPTTRKEKLEKKLEKIKTYKVDALDIPDAPLGVPKAFAPLMACYIQAVYGVKVIPHIR
LLDINTNALLNIVGGLLFCGVDNFVILQGDQPKYGNPISELNTDDALQVIRSKYGDRVSV
GCLVSLRKNVSEIVKRIVKDYDFFLLMRAVNENLEKIKVLRQIRADAKLIAYVIVCESEN
CKRLRSILEGQPIVNVERVDEHLNNLVEYVDGILLSSPGSIDTIVKVLELLNEIGIL
>A0A1G1GZ37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium GWC2_57_9|TrEMBL
MKSGSTLEKVLASGQPAVTAELGPPMSADGHEVVKKAQLLKGFCDAANITDCQTAVVRIS
SIAAAAIAYQNGLEPVMQMTCRDRNRIAIQADLLGAAALGLKNCLCLAGDHQKFSAAGKL
KGHPGAKNVYDVDTCQLVGILKKMRDEGKQEGGDPLEVAPQFFVGASWTPMGDPIDFRPI
NLLKKVNAGADFIQTQGIYDMELFRKQMEKIRNMGLHERTAILAGIIVPKSAMMLKYMDS
SVAGVSVPKEMIDRMNKAKAAAGEDKKKMKELQEQEGIKIAIELIQQALETPGVKGVHIQ
AIEWESAIEGIVKAAGLYPRPQV
>A0A1U7ZIU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nelumbo nucifera|TrEMBL
MKVIEKIRDSTLDGRVVFSFEFFPPKTEDGVDNLFERMDRMVSHNPSFCDITWGAGGSTA
DLTLEIANKMQNIVCVESMMHLTCTNMPVEKINHALDTIKSNGIQNVLALRGDPPHGQDK
FVQIQGGFACALDLVKHIREKYGDYFGITVAGYPEAHPDVISENGVATLEAYQNDLAYLK
RKVDTGADLIITQLFYDTDIFLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMTGFCKTK
IPSEITAALEPIKDNDEAVRSYGIHLGTEMCKKILAHGINTLHLYTLNMEKSALAILKNL
GLIDDNKISRSLPWRRPTNIHRVKEDVRPIFWANRPKSYISRTIGWEQYPQGRWGDSCNA
SYGALTDYQFMRPRSRDKKLQEEWGVPLRSIEDIHERFMNYCLGKLKSNPWSELDGLQPE
TKIINEQLGNINLKGFLTINSQPAVNGEKSDSPVVGWGGPGGYVYQKAYLEFFCSRRKLE
TLIEKCSNFPSLTYMAVNKDTQWMSNVGASDVNAVTWGVFPAKEIIQPTVVDATSFFVWK
DEAFEIWSRVWASLYPEGDPSRKLLEEVQSGHFLVSLVDNDYVNGDLFAVFSDI
>A0A8H5XU01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium globosum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKANLTSPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A6L4WQT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poseidonibacter sp. SJOD-M-33|TrEMBL
MFETLLQKLQEDNYLTLETTPQHEPSMHNIIERIKKFKLQNKVDGFSCTDNPLAKLKYNA
LFASLKLQMEFEKPVIATMSMRDRNKIALQSDLLGASDFDVRAILALTGDPAKMSDQPHS
KGVFESNSLMLLKIIKSFNYGMDFAGHPFKIEPKQIFPFSVVNSYAKNFATLEKKMHNKI
QNGSLGIISQPVFDIDNAKKLLESFDKAKADVEGDKKKSQLIFGLFPITKLRTALFLEAQ
VPGIHVPQYWIDQLENAHKISPEEEYKVGMRLSQDIYKEIRKIHPKIHLMTANRFDVANE
VIS
>A0A829HUX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus subsp. bolletii CRM-0020|TrEMBL
MTTNPLDRDGPVAELQDPGSIADRLTAVQPGEIAFSVEFMPPRDEAAEARLWRAARVFER
YRPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEERLLRAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTARG
>A0A4Q3T0Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacteraceae bacterium|TrEMBL
MSPHETALGPVARAGAGTAPRPSVSFEFSPPKTPEAEASLWEAIRRLEPLNPSFVSVTYG
AGGSTRDRTHRTVVRMLKETSLKPAAHLTCVEASKAEVDEVVQAYWDAGIRHIVALRGDP
PGNIGGVYVPRADGYLNATDLTAGIKAVAPFEVSVSLYPQIHPESPSIDHDIDVLKAKID
AGATRAITQFFYDIDAYLFFMDKLRKAGVTIPVSPGIMPVSNYKGLKKMAGPVGIPLPAW
LANLFEGLDKDPETRKLIACSIATEMCVRLAEEGYSDFHFYTLNRADLVYAICRVLGVRE
SEPPPVEVAA
>A0A358PT76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MRLDTILLKNDVTLSFEVFPPKVTANYESVKEAAYGVAKLNPSYMSVTYGAGGSTGGNTL
KLAKGIQEEYGVTTIAHLTCVGATKEGIRQALSDMKEAGIENVLALRGDRPKDFVGEPFI
DYHYASELVEDIQEFGGMCIGGACYPEGHVESENTQEDILNLKKKVDAGCAYLTTQMFFD
NNIFYNFLSRVREAGIVVPIIPGIMPITRPTQLHSAVRLSGCNVPMRFRSIVDCFGKNPE
AMQQAGIIYATDQIIDLIANGIKHIHVYSMNKPEVVKGIQESLCKII
>A0A1I4G6X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium salsuginis|TrEMBL
MRIKDIFETKQVVFSLEVFPPSPEVAIENIYQTLAELKDIDPDYISVTYGAGGAIKKNRT
VELSTLLKEKYDIEALAHLTCINSSPQNIDRIMTELKNNKIENILALRGDKPISGEIQGD
YTHAWQLIEQIKQSNDFGVAAACYPEGHLEAQNMQEDLNHLKYKVEAGVDYLITQMFFDN
SLFYRFREQANNYGIKIPIEAGIMPVINKKQVGKIIELSGAYFPEKFKRIMLKYQDNPVA
LQDAGIAYAIEQIVDLISSEVDGIHLYTMNNPYVAKRIKSAVGSLISHINGLKNRQKNSP
SLDKEH
>A0A6B2SYP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID10116|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTFSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGDWIAHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSPDWESDTRHFID
KCRAGADYAITQMFFDPEEYLRLRDRVEAAGCATPIIPEMMPVTNVRQLDRLPQLSNAVF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHQA
>W9VR17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cladophialophora yegresii CBS 114405|TrEMBL
MHISKKLAQAHQSNKPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
QLTCEMVNAAQSHYGLETCMHLTCTDMERTQVDDALRRAYKAGCTNILALRGDPPRDQEK
WEVKEGGFRYARDLVKYIRTEYGDHFDIGVAGYPEGCDDHRDVDMLIDHLKEKVDAGATF
VVTQMFYDVDIFLDWVKKCRDRGINIPIIPGIMPIHTHAAFLRRANWTKCHIPEDWYKAL
EPVKNDDAAVRAVGKELVAEMCRKILDAGILHLHFYTMNLAQATRMVLEDLSITPSTSGL
ALEKPLPWRKSLGLNRRDETVRPIFWRNRNTSYITRTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANIKLWGKPKSLREVTSLFVRYLQGDLDRLPWSEGAISTEAESIKDDLL
SLNKRGFLTINSQPAIDGASSTHPVHGWGPVGGWVYQKAYLELLVFPSIFKTVIERLDAN
KNLTYYAVNQKGELLTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WSKCYPAGSSSRKLIETIMGECYLVNIVNNDFHQTHEIFKVFEGLEARDLDLVFEGTEAS
DHANGTYGTREVLNGDAPVAEVEKSIANGEERKVPFPTNGVALKS
>A0A3B9IBF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MRIPDIMKQRMSVSFEVFPPKQDKPLDPLMKVLDKLYTMQPDFISCTYGAGGTNAGRHME
ICKSIHDSGKTMALSHFTCIGNTRDDIRRQMDRCLELGIDNLLALRGDIPQGWEGTRGDF
SHASELIAFLREEYGDRFVIGMAGAPEKHIEAKTFAEDIAHLRMKQDAGADFLMTQLCYD
VERFKRWMDTIRKTGVTIPIDVGIMPVLNKNSIIKMCLSMNGCSIPQPLAELISRHYNDS
DEDFRKYGIEYSTEMIYEYMALGINGVHFYSLNKADAVLEICRNCGLAYRK
>A0A5S9M5L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus safensis|TrEMBL
MTLADNSLATPRISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDIL
AITGDPSKIGDFPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNV
RHIDKAVKRLEKKKNRIRC
>A0A369TAR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferruginivarius sediminum|TrEMBL
MNAPIHLSFEFFPPADQAGEDRLWDTIQKLSPLTPEFLSVTYGAGGTTQERTNRVVRRIT
TETPNVAAAHLTCVGASQEEIAELARGWWDAGVRSIVALRGDPPRGAGTYRPHPGGYANA
AELVAGLKQVADFDISVAAYPEMHPDSPSLEADLDNLKAKVDNGANRAITQYFFEPEMFL
RFRDNAVRHGIDVPLIPGIMPVFNFAKVAAFSEDCGTSIPAWMNETFAGLDEDPDTRRLV
AASVAADLCQRLQAEGVERFHFYTLNRPELTYAVCRLLGVKPHFEEAA
>A0A559N2R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulophaga sp. RHA_52|TrEMBL
MKVTDHIKNANGKTLFSFEIIPPVKGRNIQELYGNIDPLMEFKPPFIDVTTSREEYIYID
RDGLLDKKLTRMRPGTVGICASIKHKYDVDTVPHVLCGGFTREETEYLLVDCHYLGIDNV
MALRGDAMREQKYFEPTKGGHKYAVSLVEQIQKLNCGTYLHEVIETDNCSDFCIGVAGYP
EKHMEAPSLLTDLKRLKQKVDAGADYVVTQMFFDNSKYFEFVKAAKDFGIHVPIIPGIKP
IAVKKHLQLLPQVFKIDVPQDLVDAVEDCKDNKAVRQVGVDWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAKELF
>A0A3L8PM96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium phragmitis|TrEMBL
MPAPDRSLVDALRDDRPTTSFEFFPPKDDDGEDQLWRTLSELEPLAPTFVSVTYGAGGTS
QERTVRITERIARRSSMKPVGHLTLVGQSTAEIESVLKQYLAAGVDHVLALRGDPKGGPR
APWEGHPDGMNHAIELVELAARMGGITVGVAAFPEGHPDAASLDACAEVLVNKARAGAEF
AITQLFFRASDYIELVERVRGLGCDLPIIPGIMPILNFGQVARMAELSGAAMPAEVLEQI
EPIAEDRAAVRAKGIELATQLCRDVLDAGAPGLHFMTLNRSKATREIFEALRAEGRI
>A0A3Q3FZH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kryptolebias marmoratus|TrEMBL
MVNQVQRVDGGWQSGKSDSSGASNSGGESSKESSRCSTPVLDADRSDRLRDKMRRRTESR
DHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGSDWEEEEEGFNYAV
DLVKHVRSEFDEYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLVVPEEITEVIEPIKDNDAAIRN
YGIHQAVEMCQVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWVEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLRMWGEELKNEESVFDVFTSYITAQPNGNGHQVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGQNLTNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYVHDNYFLVNLVDNDFPLESCLWQVLDDMFELLDATLELLGEQVAP
LGAQATSLGAQAEPLSVQTLLGVQTEPLDAQAEPLNSQTEQLDAQTEPLNSQTEQLDAQT
EQLDMQTEPVSVQTLLGVQMAPLGEQTAPE
>A0A1C5FN79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MnatMP-M17|TrEMBL
MRDLLATGKTSFSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRAGTVKA
TERIASDTTLTPVAHLTAVGQSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVKHP
DGVRYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWETDTRHFVDKCRAGADYAITQMFF
EPDGYLRLRDRVGAAGCATPIIPEIMPVTSVRMLERLPQLSTAVFPAELKERILSVKDDP
AAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYENLGLHEQS
>A0A372IEV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium W635|TrEMBL
MTQPTPRVSFEFFPPQSLEASFRLWDTLGTLAPLAPQFVSVTYGAGGTTRDLTHDAVKTI
NANYGVPVAAHLTCVDATRDETLAIADSYAEAGVNRIVALRGDPPKGSHGFHPHANGFAS
SVELVEALARRGNFEIAVGAYPDPHPEAENLQACVDYLKRKVDAGATTAITQFFFEAGTF
FRFRDACADAGITAPIIPGVLPVNNWTRVRRFATNCGAVIPQWVDAAYETAIRDGREALL
STALTSELCTELLEGGVEDLHFYTLNTPDLTRDVCAALGVTPQVALAEVA
>A0A7Y4B7A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio alginolyticus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSAKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKATTGLVAAPHLTCIDATREELINIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFD
GLNDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRAVVGA
>A0A8G0A6K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apibacter sp. ESL0432|TrEMBL
MKVTEHISNAKGKTLFSFEILPPKKGEDLQNIFSNIDPLMEFNPPFIDVTYHREEYEYRE
LPNGLIQKIVTRKRPGTVGICAAIQQKYKVDAVPHLICGGFNKEETENILIDFNFLGIDN
ILVLRGDPIKSEGIFKPHSQGHSYANELVSQVQNMNSGKYLHEEYAHGATDFCIGIAGYP
EKHFESPNLDTDLNYLKQKIDAGADYIVTQLFYDNTKYFEFVKKCRNIGITVPIIPGIKP
VSIKKHLTILPNIFHIDMPQELVMAVEKCKDNKAVYEVGIEWTVNQCKELMKQGVPVLHF
YSMGRSENIRKIAKQLF
>A0A8H6TSA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycena chlorophos|TrEMBL
MKLTEKIQALKPSRPFFTLEFFPPRTDQGFENLLPRISRLSALNPLAISITWGAGGSTKE
RTLELAGVSQEEYGLDTILHLTCTNMVQGMIDEALQEAKQRGITNILALRGDPPRGEEEW
TPIDPRFKNGTDLVKYIRSNPDYTSHFCVGVAAYPDGHTGQLDDERAEIEYLKLKVDAGA
DFIVTQLFYDVDGYFQWEKKVREAGITVPIIPGIMPIQTYASFLRLTKLTGARVPESVLQ
ALEPICNDDQLVKEYGVTLAIEMIKRLTEEGQVRGVHISTLNLEKSVQRVIEDLKWSEIP
SSPLINHNKLIEEIPQLNDLTITPSTAATSATLGLANLPIAVETEAGRGELNNASSWDDF
PNGRFGDFKSPAFGSTDLWGGPAIGPADVLRHCGHPKTHADLTTIFLDYLHSRIPITPFS
PTALSPESLSIMPHLERLTKAGWWTVGSQPAVDGARSDDPVVGWGPRAGYVFQKGFVEFF
CTEAEVDRIEQKALDVGWVHWFAGNKKGECRGNVPENGRNAVTWGVFPGQEIVQTTIIER
ESFLTWKEEAFSIWADWASLYRPGSTERKLLEDVADERWLVSVVHHDYRDPKALWTFVLD
A
>A0A7Y5QV62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTDHLRKATATLFSFEILPPLKGRDIRSIYEGIDPLMEFGPSFINVTYHREEVLYKDM
GHGLLRKVRLRKRPGTVGICAMIKAKYSVDTVPHLICGGFSQEDTEDALIELNFLGIGNV
LALRGDAVKNEGHFVPERDGHAHAVDLVRQIAALNRGRYLHEEETETAPTDLCIGAACYP
EKHPEALNLDTDIAYLKQKVEAGAEYLVTQMFFDNAKYFAFVDRCRAEGITVPIIPGLKP
LTNRKHIAFIPKTFHLDLPVAFSTELAKCRNDEEVKQVGIAWGIQQARELMARNVPCLHF
YTMGRSEAVRAILKAVR
>A0A077ULV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus schweitzeri|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A7Y5F656|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MRVIDRISKSKSTLFSFEILPPLKGKGIEYIYEGIDPLMEFKPAFINVTYHREEFAYKKR
EKGYLEKIAIKKRPGTVGICAAIKSKYDVITVPHLICGGFNKEETENALIDLHFLGIKNV
LALRGDAIKTEVAFVPEEGGHAHAVDLVKQIVDLNKGIYLDEEIVSPHPTDFCIGVAGYP
EKHFESPNILNDIKYLKQKIEAGAEYIVTQLFFDNQKFFDFVKLCRNNDIHVPIIPGLKP
ITTKHHLSFMPKFFHVDLPGVLVEEIEKCKSEEEVRQIGIEWTIAQSKELIKFGVPCIHY
YTMGKSEAVKKIASHAF
>B4SJY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia (strain R551-3)|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEDGAPGLHFYTLNLAKPTTSVLKLLQG
>A0A7Y0N2E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio alginolyticus|TrEMBL
GGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRAITQF
FFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFEGLDD
DPVTRQLVGASQAIDMVRVLSREGVKDF
>A0A328HAC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter globiformis|TrEMBL
MSPPSLIETHPNLSDTAPVALSYELFPPRSPAAAETLWNTIRELEATDPDYVSVTYGASG
SNRDTAVELINRLVLETTLRPLAHLTCVGNTPTELAEIIGELLDVGVRGILALRGDLPKD
SGESVSGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFRTEQYADLVTRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAPELIERMAAADTDAERLRIGVSATVDLANAALDAGAPGLHIYTFNEHQSALEVLDKLS
LARPARPSSRLNALARRQLAS
>A0A2E4KB64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVKEHLSKSKETLFSFEILPPLKGTSINSIYKTLDPLMEFSPPFIDVTYHREEYVYKKK
KNGLLERISVRKRPGTVGICAAIMNKYHVDTVPHIICGGFSKEETENALIDLNFLGIDNV
LVLRGDPIKSETYFSPDKNGHQYASELLEQVIDMNNGNYLDDELSNSSPTDFCIGVAGYP
EKHFEAANMRSDIHFLKKKVKAGADYIVTQMFFDNQCYFDFVKMCRENDIDIPIIPGIKP
ISTLNQLKLLPHRFHLSLPNNLVDEVLKCKNNDDIRLVGIDWAKEQTRELIEFGAPCIHF
YTMGKSDNVQQIVSDFK
>A0A2E7VQA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVIEHIKNTNKTLFSFEILPPLKGESIQSLYKSLDPLMEFQPPFIDVTYHREEYVYKRK
DNGLLERRSVKKRPGTVGICAAIMNKYNVDTVPHIICGGFNREETENALIDLNFLGIDNL
LVLRGDPIKSEIYFSAENDGHSYASELLMQVSDMNKGIYLDNDLRNTVSTDFCIGVAGYP
EKHFESPNMFSDIHFLKKKVEAGAEYIVTQMFFDNQKYFDFVKLCRENDIHIPIIPGLKP
IATKKQLTLLPQRFHLNIPSELVNLIIKSKNNDEVRNIGIEWAINQTRELIEFGVPCIHF
YTMGKSDNIQKIVQKFI
>A0A2E7TMD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MLRDKILNKESGIVLYGMTPPKENTDVSRVREIASKHLNRIQSLDIDGVVLYDIQDESAR
NNQERPFPFLPTFEPQKYSGDFLSELNLPKVLFQVVGKHSEDSLKNWMLNNVNKGDLGVF
IGNSSSSQSSKVSLEKAYSLRNEFASEMLVGGVAIPERHFAKKDEHLRITSKIKSGASYF
TTQAVYNVEASKNMLSDYYYYSKSNNLPLVPIMMTFSPCGSKKTMEFMKWLGIHFPKWLK
NDLTHSEDILGASIDTCVRTFKELVNFSLNKGIPIGANIESVSIRKDEIDASVELLENVK
DILNKNL
>A0A4Q9R044|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas kirkiae|TrEMBL
MSSPDRRYSFEFFPTKTEAGHEKLLATAKRLAGCNPDFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDSKAELLELLNLYRDNGIRRIVALRGDLPSGMGMASGELRHANE
LVEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKARAGADSAITQYFFNADSYF
YFVERVRKLGADLPIVPGIMPITNYSKLARFSDACGSELPRWIRKQLEAYGDDIESIQAF
GEQVISEMCEKLLAGGAPGLHFYTLNQAGPSLAIWNNLKLSN
>A0A2K8KJK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reinekea forsetii|TrEMBL
MNTPVPVSFEFFPPKTDIGYDKLLTAHDELKIAQPEFFSVTYGAGGSTQERTINTVIELN
SRGVPAAPHLSCIGSNRATVQALLEQYQAAGINRIVALRGDLPSGMRGTGGDFNHASDLV
TFIKAEFADTFSIEVAAYPEMHPQANSFDQDVDHFVAKAKAGADSAITQYFYNINAYKHF
VSEVRRRDCDIAIVPGIMPITNFTNLARFSDACGADIPRWMRQALQSCGDDVTRIQRIGL
NFVVDLCQELIVAGAPKLHFYSMNQSAPTLAILAQLEGFKA
>A0A2A4Z2P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTEHLKKAKKPLFSLEILPPLKGKGIQSIYDGIDPLIEFGPAFVNVTYHREEFVYKKR
EKGYLEKISIKKRPGTVGICAAIVNKYKVDAVPHIICGGFTKEETENALIDLDFLGIDNV
LLLRGDPIKTEPAFIPEKDGHHYAVDLVNQVVGLNNGEYMDEDLQNAAPTNFSIGVAGYP
EKHFEAPNMKNDLKFLKQKVDAGADYIVTQLFYDNQKFKDFVKLCRECGITVPILPGLKP
ISTKKQILALPKFFHIDLPDELVDAIEACKDNDEVKQVGIDWAIKQSKDLLDFGVPCIHY
YTMGKSLAVREVVKAVFG
>A0A2D9ITK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTEHISNSKDTIFSFEILPPLKGKGIEDLYAGIDPLMEFNPPFINVTYHREEYQYKEM
GNGLLKKVSVRKRPGTVGICAAIMNKYKIDAIPHLICGGFSKEETESALIDLKFLGVDNV
LALRGDPIKSEQIFTPAQGGNAYALDLIKQMDEMNQGQYLHEETKNNPSNFCIGTAGYPE
KHFEAMNMSTDLKYLKMKVDAGADFIVTQMFFDNSKYFSFVKKCREIGINIPIIPGIKPI
TTLKHISFLPKFFHIDFPEELSLELSKCKTNEQVKQVGKEWGISQAKELKNNNVPVIHFY
TMGKGESVKNIAKAVF
>A0A2W4HRG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Margulisbacteria bacterium|TrEMBL
MLYKSRLHKDLLTKKFVVTAELSPPKGVEYNYLLDQAEALSTYVSAFNITDNQRSTMRMS
ALAICHLLESQGFETIFQITCRDRNILALQSDILGASALGIKNILAITGDYPLSGDHPFA
KPVFDIDSVQLVHLLKQVMPGGKDFAGKELKGSPDFIVGVVANHGAQPQEPQLIKLQKKI
NEGAEFIQTQTIYDIDQFLEFLEEVPPAVSVLGGIFPLKSAKIAHFLNDNVPGVSIPETI
LRRMENTKDPYKEGIEIAVETIEAIQPECAGVHFMTMGAVDVIAEILKEVSIDK
>A0A3C2AP28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
VQLNNGNYLDEDLNNVKETNFCIGVAGYPEKHIKAPNRKTDLRFLKKKVDAGAEYIVTQM
FFDNKAYFRFVDDCREAGITVPIVPGLKPLTTKKQTGILPSMFHIDVPADLYDEVEKCKN
NEEAAQIGTEWCIAQSKELVAAGVPCLHYYTMGTSGSTKAVAEKIF
>A0A3D4CKE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
QLTFIPKFFHVNLPDELVDEIEKCKSDEEVKQVGIEWGIKQSKELIQKGAPCIHYYTMGK
SSAVKEIARAVF
>A0A316AE10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter jejuensis|TrEMBL
MTKVTDYIRQASGRTLFSIEIIPPLKGQNIEELFRSIEPLMEFKPPFVDVTYHREELIDR
PGSNGQLIRVPIRKRPGTVGICARLMERFKVDAVPHVICGGFTKEETEDVLIDLFYLGID
NVLVLRGDAEKSAGVFMAKEGGHHYASELLQQVVNMNQGSLLNEETQSHPTDFCIGIAGY
PEKHMDAVSFESDFSYLKKKIELGAEYIVTQMFFDNKKYFDFVDKCRAEGITIPIIPGLK
PLSTRRQLEILPKIFHLEMPEDLSKAVLGAHSDKDVRQIGVEWGVQQCKELVAYGVPVLH
FYTMGKSDNVAQIAREMF
>A0A2G6F4N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTEHIQQSKGKTLFSFEIIPPQKGNNIEDLYTNIDPLMEFNPPFIDVTTSREEYIYID
KNGLLDRKITRMRPGTLGICAAVKHKYNVDTVPHVLCGGYTKEETEYLLVDCHYLGINNV
MALRGDAMKHQKYFEPTKGGHTYANELVHQIANLNKGKYLHNVIETDNCTNFCVGVAGYP
EKHIEAPSFQTDLRRLKEKVNAGADYVVTQMFFDNKKYFEFVNAARKEGITVPIIPGIKP
LAVKRHLQILPQVFKIDLPEELIKAAENCKSNKEVRQVGIEWSIKQSKELLKAGVPVLHY
YSMGKSDNIVAIAKKVF
>A0A6S6UXL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenophora teres f. maculata|TrEMBL
MPKTWTDRGQTSRPSIGAPPGAFQGDKMEKITDKINSLPDGANYFSLEFFPPKTAMGFAN
LQTRLERMSQALRPLFVTVTWGAGGSTATKSLELAEICQRQLGLTTCLHLTCTNMNRQLI
DDALEQAKVLGIRNILALRGDAPRSEEYRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDY
FCIGVAAYPEGHSDQSHPEHQDPLSDLPYLVEKTKAGADFIMTQLFYDVQAYDKFEKMLR
EHESGVFKTIPIIPGLMPIQSYKILLRTTKLSHARLPTEMLSRLDAVKSDDELVKQVGIQ
IMDEMVEHIKARPNSCRRGFHFYTLNLEKAVSHVVEDTHLIPTTIMDDEEVIVETTPAIN
LEPPPNGLMAHRRRSSAVNSGPFNRVIISHGSGAKSSNHSYEATEEEAGVPRGPINTRAN
TLAISEGEGSLGREATWDDFPNGRWGDARSPAFGEIDGYGPTLHVSTPQALKLWGYPVEK
KDISTLFRRHVEGDLEAIPWSEQGLSPETSTISAQLLALNAKGWWTVASQPAVNGVKSTD
PIFGWGPKNGYVFQKPFVEFFIPASEFQALKPKLQAHDQVTWFAGNAAGAFEASQEDGVN
PVTWGTFAGKEIVTPTIIEAVSFRSWLDEAFSIWKEWQRIYPPRSESSVLLGDLSKDVWL
VNVIWGDFVNGEGLWEFLGK
>A0A6S6UWZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenophora teres f. maculata|TrEMBL
MHISKKLAQAREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQTVYGLETCMHLTCTDMEKSKLDDALREAYQSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGGTF
IVTQMFYDVDLFLEWVGKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTRCNIPQHWTDAL
EPVKNDDVEVREVGKILVADMCRKLIAAGITHLHFYTMNLAQATRMVLEELDLLPDGEAP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNVKLWGTPMCIRDLSDLFVRYMEGKLDSLPWSEQAITTEAGPIRSDLID
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDIVDTWYLLNIVHNDFHETRGIFPIFDGLEVKDMDKPLYNPSVDL
PGVNGSEATNGTNVTNGEAEAHKKEAPGLIETAKAAAVEVTNGIKSLAVSN
>A0A8H9FV95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Knoellia flava|TrEMBL
MAPRSIPALLASARPSVSFEFFPPKDDASEVVLWDAIRRLERVRPDFVSVTYGAGGSTQD
RTVRVTERIARETTLTPLAHLTCVGASVADIRRVVGQYAAAGVRDILALRGDPPGNPGGE
WVAHPEGLNHATDLVSLIRTLGDFTIGVAAFPDVHPASPDLDHDVEVMVRKADAGASFAI
TQMVFDADTYLRLRDRVAERRDLPITPGLMPVTNLKQITRMSQLMGTPLPRAVVDRLEAV
AGDADAVRAVGVEIATELAQRMLAEGAPGLHFITMNRSTATLEVHENLGLSTGAR
>A0A3G6X173|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus elongatus PCC 11801|TrEMBL
MNMRRFREAVAAGEFLITAEVAPPKGADPSGMLVHAELLRSRVHAINITDGSRAVMRMSS
LAATVLLRQRGIEPICQVACRDRNRIALQADLLGAQALGLDNILALTGDPVKAGDSPEAR
PVFELESVRLLQLIQKLNGGLDIHDKPLPDGASDLFAGAAVDPQLKSWSGLERRFWRKVD
SGAQFFQSQLICDFDRLDRFMEQIARPSGRPVLAGIFLLKSAKNAEFINRNVPGVQIPQT
IIDRLAAAADPLAEGIAIAAEQVRWAQQLCQGVHLMAVRREDLIPAILDQAGIAPLQPTS
DRQPSTLLMP
>A0A4Z1DME7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseoluteus|TrEMBL
MALGTASTRTDRARTVRDILATGKTAYSFEFYAPKTPQGERNLWNALRRVEAVAPDFVSV
TYGAGGTTRATTVKETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEILPVTSVKMLERLPKLSNALF
PPELKERILSAKDDPAAVRSLGIDFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A418KTK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiangella rhizosphaerae|TrEMBL
MFFSLVPPRLATSPDEAQRIADVTLQRLEPVDLDGLILYDIDDESDRNPEQRPFPFLPTM
DPADYARKNLAKWELPVLVYRAIGKYPENELRSWLGGLDSDRLLSVFVGASSRDKTVATS
LRRAYALRSETRPDLLLGGVAIPERHRRRGDEHARLIDKQDNGCSFFVTQVVYDVNAAKD
VVSDYHYACVERGISPVPVIFTFSVCGSMKTMRFLQWLGVDVPRWVQNDLRNADDTLDAS
CEQSLATAVELATFCRRLGMPFGFNVESVSIRRVEIEASVQLAARMRDVLAVASRIESQA
GDDR
>A0A368W0W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus prosopidis|TrEMBL
MKQGSDPPKLRTLPEMVQEQTTIIVELDPPRDLDYSPFLEGAIALKEAGADAVTMADNSL
AMTRISNVAMGTLVRERVGIRPLLHVTCRDRNLIAQQSHMMGLYALGIDHVLIVTGDPPR
YGDLPGAAPVFDTTSSEMIRMIKKLNEGISFSGRPLKACTTFTVGAAFNPNTRHLNKSVE
RLEKKIAAGADYAMSQPLFCHQQIELVAQATQYLAIPIFIGIMPLTSYRNAEFLHNQVPG
IRLSDDVLARMARFQGEDARKQGLEIAMELVDTVYRSFKGIYLITPFMRYEMTAELTRYL
KSKR
>A0A2M8MMT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLESAGINIPVAPGIMPITNASNLIHFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A7H9AYQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygotorulaspora mrakii|TrEMBL
MKITDKLEKHQEKSAKPTFSFEYFVPKTTQGVQNLYDRMDRMYETSFPQFVDITWNAGGG
MLSQLSTDLVATSQSVLGLETCMHLTCTNMPVSEIDDALQRAYESGCENILALRGDPPLN
SKEWTPVEGGFRYAKDLVKYIREKYGDHFGIGVAGYPEGHPEDNDDRDKLVEYLKEKVDA
GADFIITQMFYNADIFIKWCEAVRAAGVSVPIIPGIMPITTYAAFLRRAQWCEINVPDEF
MKKLDAVKDNDQTVREIGTDLLVSMCQKLLDSGFVNHLHIYTMNLEKAPIMILERLGLLP
TDKDVSDAAVAVLPWRKSLNPQRRKEEVRPIFWKKRPYSYVARTSQWAVDEFPNGRFGDS
SSPAFGDLDLCGSSLIRQSGKKSLELWSRPKTVEDIARLVIRYLERDLNCLPWCDVALNN
EVDVILEDLISLNQNLIITINSQPQLNGIKSSDPVFGWGPKDGYVYQKQYLEFLLPKEKL
YKLQDSLKDNTMLTYFAVDYEGNLTTNHPDDYKANAVTWGIFPGREVLQPTVVEKISFLA
WKEEFYHILQEWKLNFQNNQIQESVVLLDHLIGDYVLVNIVDNDFVSIDNKMLKLLHEI
>A0A8H7LTW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKVTEKIQQAEKDGRIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTNELVKTCQGVIGIETCMHLTCTNMPQEKVDVALREAKANGCRNILALRGDPPSGQEE
WTTVEGGFQHGIDLVKHIRREHDDYFDIAVAGFPQTIQLPEAEAKQEMQWLKEKCDAGAN
FIFTQMFYDADMFIRWVKAARDAGITVPIVPGINPIQTWNGFIRATTLSGTDIPQDLMDI
LEPHKNNDEKVRELGTKIVSDLCRKILDADIGIKGLHFYTMNLEKGTKMLLEELNLVPRV
ETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQTPEEGRKIWGTPTTIDDVKALFTKFCTQQIKALPWSDQPPTTEMLVIGQQLA
RMNELGYLTINSQPAVNGARSDDKAFGWGPKNGYVYQKAYLEFFVHPSQLHALIKRIERD
TNVTYYAINKQGDLKTNSTSEGPTAVTWGVFPGKEVIQPTIVEAVSFMAWKDEAFELGCQ
WAKIYEPESPSRKLIENMMDEYFLVNFVHNDFHDREAIFRPFFADAGLQTNGDTETPAVN
GVKHVNGLVNGHSTAVRA
>B4GZK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila persimilis|TrEMBL
MRKERDGQTNLLRDGNQRTPRMPHHVSRYALCRKGMCSAPRCANSVGISVMDTQTRHSTL
NGGHMTMTIIALDEDEDKDECEEGNFIKRESKALLPGPKKEEEEEDVDVDVDRAEADRNC
GDSWRNRQLWPTRSSSSGNKGESESRKNIVASVRRFDCGLPQRSDDRRAITHTNVKLIRT
SAKSIRETVTAADRYSRYQAQFRAICQRVSIFESDCEMHATETVPSIGLASTSYVLCVHY
ATPPERDRSPGAARGGSGGGADGEAAAPGITVPIVVGQLVADSFRTYCLSENIAGVHLPP
GLRSELLAIESDAERVSQFFIQLSIRIIRDILAADVGVYGVQFYTFNQFAPVQAVLKELR
TLDILKDEGGQ
>A0A8F8F2X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia sp. R33|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSEEMEQTLWKSIDRLKNLKPKFVSVTY
GANSGERDRTHSIIKDIKDKTGLVAAPHLTCIDASKDELKSIARDYWNNGIRHIVALRGD
FPDSSHKPDMYATDLVELLKGEADFDISVAAYPEVHPEAKSAQADLINLRKKIEAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKMTNVRIPAWMSKMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A7W6D3R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hansschlegelia beijingensis|TrEMBL
MPNKRLSRSGRRPIRVSFEFFPPKTPEMEDSLWRAVQRLAPLQPNFMSVTYGAGGSTRER
THATVARMVKETDIPPAAHLTCVSATREEVDAVVDSYREAGVRHIVALRGDPAGGVGAKF
EPHPGGYGSTAELVSGIRSRAPEIELSVSAYPERHPESPSEEADFDVLKAKVDAGANRAI
TQFFFDNAHYLRYVDKARARGIHIPIVPGIVPVSNFRQTASFATRAGASIPDWFAARFEG
LEDDAPTRQLIAASVAAEQVLDLVDHGVTDFHFYTMNKADLVYAICHLLGLRPAREATAK
PAAAA
>A0A8C9IJ44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piliocolobus tephrosceles|TrEMBL
MDHRKARVLPAGHYCPSLGIWASQAGSVRFSVPPSISRNLAMVNEARGNGSPNPCLEGSA
SSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDTLELLNRPTQNERETETP
>A0A413G0W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerotruncus sp. AF02-27|TrEMBL
MILSDGQLSHRTLHACGIIKRKCLRGGDRVPAGPLFFDGAFGTYYLRLTGDERPCELANR
TDAQTVRKIHREYLEAGSNAIKTNTFAANPSLEADPERLYAVIKAGWENACAAAKPYGAR
VFADIGGSELETAAADYEQIAGWFLSLGAKDFLFETLAEYALIVPAVEKIKKAAPDASVF
VSFAVSPDGYTRRGLHYRTLLGEAWENGGIDAAGLNCVCGPSHMLKLAGSLGGFPKPFIA
MPNAGYPSAINGRVVFEDNADYFAQKLAELYETGADILGGCCGSTPRHIALASERVRRAE
RREKTVQPSGQHGISETRRKNTDFLARTDKVIAVELDPPLDYDCSFLLSASASLKADGAD
MITIADSPLSRPRADSVMMAARIRREAGIEVLPHITCRDRNQNALKASLLGAASEGISRI
LALTGDPPIQTGGRKPDGVFSFNSYDLISFIESLNDELFTENPFLVAGALNVNAVNFPAE
LARAQRKVALGAKMLFSQPIFSREAVENFRAARAALGCKLFAGILPVAGYRNAVFLANEV
SGIEIPPDVVERLRDKTPEEAAEISIAYSAGIARQIYDEADGFYIMTPLRRVAIVRGLMR
EIKKMGETGR
>A0A5B1QHW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dentipellis sp. KUC8613|TrEMBL
MKISKKIEQAAKEDKIWWSFEYFPPRTAQGLQNLLDRIERMRQLGPEFIDITWNAGGRTS
DLTSELVKTCQGLIGIETCMHLTCTNMPKEKVDIALRDAKQHGCRNVLALRGDPPAGKEE
WEAVEGGFVHGIDLVRHIRKEYGDYFDIAVPGFPQMQLLPPEERALEMKYLKEKIDVGVN
FIFTQMFYDVDLFIEWVKTVREAGITVPIVPGIMPIQTWGGFQRATSLAKTIIPKSFSDA
LEPHKTNDEKVREIGTKLVADLCRRILAADIGIRGLHFYTMNLERGTKMLLEELNLVPRV
ETIKPLPWRQSLTPSRRSETIRPIFWANRTKSYLTRTENWDEYPNGRFGDSRSPAYGDLD
GYGVWIKQTKEDALKLWDHPTTFTDLTSLFARFCKGELAALPWSDEGLLTETSVITSQLA
RINELGFLTINSQPAVDGARSDDKVFGWGPSNGYIYQKAYLEFFVLPDLLDILIRHIEKD
HSVTYHVINQRGDLRTNTTSDGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGRQ
WAKLYEPETESRKLIDDLMARALLVNIVHNDFKKPDAIFEPFLKAGAEYASLKANQVNGN
GHAH
>A0A2S7EDJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas euvesicatoria pv. citrumelonis|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGAAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCQRLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1G4KFF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea meyersii CBS 8951|TrEMBL
MSTIKELYEASPGPFVSLEFFPPKTQSGKQNLTARMGRMTALNPLFLTVTWGAGGTTAQK
TLDLAALAQRELNIPVCMHLTCTNTSKEVIDHALKEAHKADIRNILALRGDPPVGEDWEE
GSNFSDFQHAVDLVRYIKSEYKDDFCIGVAAYPEGHCEGEADVIDHSAVRDLPFLKEKVE
AGADFVITQLFYDVEKFLDFERLFRDEVSATLPLFPGLMPINSYQLFNRASKLSHASIPS
SILDRFPSESRGDDNKVRAIGVDVISEIVDTIYTRTNGRIKGLHFYTLNLEKAVAQIVTN
SQCLSKILEEDKDEDLVDGIEEIALEDSDISGNDNMKKRRRQSSVHNTDRTSNRVLIDDQ
DKNIIEGREPSGAPSRKVVLSISQGSGSLGRDATWDEFTNGRFGDSRSPAFGEIDGYGPS
LKVSSQKAYKIWGQPQRFQDIQSLFVRYLEGALDALPWSDLGISSETALIQEELIQLNER
GYLTLASQPATNSTPSTDKIFGWGPRGGYVYQKSFVEMFVHKQQWDNVLKPKLDPSSPNV
SYYVGDSSEAFYSSLDTNCSSVVTWGVFPNSEILQTTRVEEESFKAWRDEAFSIWLEWSK
LFPRGSATNSLLRQIHRDYYLVSIVHHDFSQCDALWDLLLG
>A0A1L3L436|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium americanum CCGM7|TrEMBL
MSPDVNPFDPSAPLDALPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYDRAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHEATPTETLVAERLGHLREGIEENQQQMAEAAAH
HPH
>A0A229RIK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis thailandensis|TrEMBL
MDLVRLIDRAAGEFLLFSLTPPRLATAHDRVQEIADATMARLRPLKLDGLILYDIDDEAA
RNPAQRPFPFSPTLDPANYLANNFASWQTPVIVYRAVGKYAPSELRSWLAAQDPARVMTV
LVGASSSKVDAMTSLADAQALRRDTNPGLSLGGVAIPERHSRRDDEHLRLLAKQEAGCRF
FVTQVVYDINAAKNLVSDYHYECVAREQAPVPIVFTFSVCGSLKTLDFLRWLGVDVPRWI
ENDLRHATDTLETSYQVAVAAATELMSYCRGLGVPFGINVESVSIRREEIEASVRLAEHL
RTKLKG
>A0A1B2R873|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella sp. H567|TrEMBL
MTDTTTPAYSLEFFPPRDIAAQERLLRAAKQMLAIHPRYVSVTFGAGGSTREGTAGTVRM
LRNLGVDAAPHLSCVGATREDLRAILASYRDEGVRQVVALRGDMPSGMGGDAGELKYARD
LVAFIRQETGDWFHIEVAAYPEMHPQADNPSSDLDHFVDKVRAGANSAITQYFFNPDAYF
DFVERAAAKGVSVPVVPGIMPITNHTQLARFSQMCGAEIPRWIRLRLAEFGDDKASIRAF
GVDVVTDLCRKLLDGGAPGLHFYTLNSAEAPMAIWKNLTST
>A0A2E4AT53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MSVTVEAIAKAGANWSIEVTPTGATKIDSFAAVLAENTSVNVTFLPGTDPNETIAVAKRL
SDEGMNAIPHIAARSLSDKDQLDGLLKRMTSEANVSEVLVIGGGVDKPVGAFDNTMQVLN
TGLIQKHGISRIGVSGHPEGSPDIHDDALAQAIADKNAFAASEGLGLYMETQFCFDAAAV
LAWERAIREAGNALPIRVGIPGPATIKTLFRFAQISGIGPSMRFXAKQARNVAKLMTVQS
PHLLLAGLADGMASGASDADKCLIQHFHYYPFGGFAKTAAYADAIAKGQIILTKDGGFDV
QDS
>A0A1B9KYD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNQKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVPPKDDF
RFASELVTFIKENGDFNVIGACYPEGHLEASTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKAHDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVATLLAVPKSK
>A0A127MDA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingorhabdus sp. M41|TrEMBL
MSKHPIHPNWERAPVGVTEGYSLEITAKDIDSLRDAAPLIAADTPVAVTFLPGEEQAARV
AAAVAVRALGFEPMPHFSARRISSSDEFEDYLQAVVRNAGVQRCFLVAGDPPEPEGPYFD
SSALIESGAFERAGIKAIGIGGHPEGHPVMSKEQCWEVIDKKIAAIESRGMAPLIVTQFG
FDPDIVLAWLEELRSRGVEAPVRIGIPGPAGIKRLLRYAKYCGVGASASVLAKYGISLTR
LMGSAGPDKLVDRFSAELGSEHGRVRLHFYPFGGIDKTVEWIADYNRRHDI
>A0A5D3FG90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura decatromicini|TrEMBL
MAFEIVCEVEPPMKPDLTRVRHQIGVLSPVADSFLIPDNHIGRATVSSVAVAHEVQAMGA
RGIACLNSRDRNLLGFRRDLLTAAAYGVDRFLFVYGDKPSIGGRTSELTVRAMMDETRAA
AEDAVFAGCGPFRIGVTTGLRKTPEWKRSADFTFVQVSYSVDDLLRWRDDARLNGPVYAG
VMVLASAGMARNLAAAIPDIAIPAELVDAVERDGRAGVAAACEQVLAIRDSGAFDGVHLV
PVSRYREVAARLEREL
>A0A7Y3AI30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MLEIPYIIEILTPRRSPEGNIDQLLDRFAERFQLIMEAGCALSIPDNPMGQLRLGALESF
DLKGLTFDPETVMMNLNTFHDKDELDALLQKAADFGLKYILVIRGDGGPHLPRLDPKSIG
GSHNITTTMDLLRYINSEFSDTFVTGAAFNPYKPMPFELDRAHQKMEAGAQFIVTQPVIG
RNEHIDSLGIICENVVVEAWMSTNIDLFYKSVGRERIEQAEHYDPLENLSELHEAYPHCC
IYLSMLSFKQDWRHLLPRLTH
>A0A800C7F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKSGSNLERLLASGQFAVTAEAGPPKGTSPKVIQRKGELLKLCCDALNVTDNQTAIVRMS
SMSGCVLLKEQGVEPVLQMVVRDRNRLGLQSDLLGAAALGIRNVLCLSGDHQKFGNHPAA
KGVYDIDSIQFVRMVKTMRDEHKFINGEEISGDVPFFIGAAANPFADPFEFRVTRLAKKV
NAGADFIQTQGIFDVPKFVKWMKMVRDRGLHERTHIIAGLIPMKSVGMARYMRNNVPGLS
VPKELVDRMADSKDPKEEGVQICIEAIEQLMDVEGVHGVHIMAVAWEDIVPRIVEEAGLM
PRPVV
>A0A7Y3AD30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MRLKDALKKDKFIVTSEVQSPIDDSPEDLIENLKLVRGRVDGFSVSEIEIEGVVGDTIKA
CDLLKKNKFEAIYQTTTRHKNRLQLQKDLLNAHDAGVENLLVFTEDYRITGDSLQEMMFF
HVDSGKLSSVLDHLKQGHTVEGDELAQKAEFVLGSGVESSWGKNVPELEMKEMEEMTKIG
TGYFLTTPVFNLDQFEKFIKNVDTFGVPIIAEVLIIRTAGMGQFLNRHMKPGLVPDWVIK
KLARAPDKQKASIEIFADIVSGLKDICQGVHIISIGGEQRLRHYLDAAKLK
>A0A8D9Y9D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae PID1|TrEMBL
MNYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A6P6XPX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dermatophagoides pteronyssinus|TrEMBL
MQEKVKKHSTNGSSGFVPLSSKLTERSQSREVSFFSIELFPPKTWKALDNLVPLLNNFRQ
LGSLFSTVTWHSTMNQLDNMDDILSMQVAEIALNYCWLDTMIHLTCVDMTTDKMLAILER
LKQIGITNILALRGDLNENTVGDFHYASDLVGFIRHHYGDYFTIAVAGYPIKHPESMNKQ
QDRENLKKKVDAGADFIITQLFFEADVYIDFVDECRAIGIEVPILPGIMPIQSYDSLTKI
TRLSQLDIPNRIIQDLEPIRNNDEAVRNYGIEWTIHLCRQLMQSGRTPGLHFFTLNRQHA
TATIVKALEIGYSFCHKPLPWKQPVNHRRCSENVRPIFWSGRPESYVQRTNTWDEFPNGR
WGRVHSPSFGSLNDYHLFAALDSITPKNRKRYAAMWGKQLLDEQDVWHIFEAYVAGTNNR
FGHKVESLPWNDEGLAPETNVIRHRLSHLNRHGILTINSQPNVNGISSSDSIHGWGSPNG
YVYQKAYVEFFISQHKIDCLLKILPHYPLVNYQITNSKGDPFYTNCDEDEPIAVTWGVFP
GKEIIQPTIVDVVSFKVWKDEAFSLWMNKWARVYPDEDVESHSVLGSICNTYYLVNLVDN
DYPNETCLWSILEQVIVSNHCTSSSHEV
>A0A1W9SP60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwiniaceae bacterium 4572_131|TrEMBL
MKNYSQYHQDIMNQKLENIRNNIQCSFEFFPPKNSFLEENLWSTVNRLSLLKPKFFSVTY
GANTGEREKTYDTVQKIYKKTGIITAAHLTCIDSTPHKLKEIAYNYWNSGIKSIVALRGD
TLEKDYRHTMYAVDLVLLLKKIADFDISVAAYPELHPESKNVKSDILNLKKKVDAGASRA
ITQFFFNIESYLRFRDNCIKNKINIDIIPGILPVCNFQKLKRFSSMTNVKVPKWMLDMFN
GLDDDIFTQKIIGSSIAIDMVKKLSCEGVKNFHFYTLNQSDITYSICHILGL
>A0A1H0FMU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfonauticus submarinus|TrEMBL
MIAELLNKTDFFISLEFFPPKDREKWPSFFREVELLKKINPLFVSVTYGAGGSTRDYTLE
IVKILKQDLSLEPMAHLTCVGASEQNICSFLDSLQKIKVKNILALRGDPPKGEKSFVPDS
DRFKHASDLVSFIREKYGKDFSLGVAGYPEGHIEALSLESDLEFLKLKLDLGGDFVITQL
FFDNNLYFDFVNRARSLGIKKPIIPGILPIMNLKGIKRITQLCGATIPEELLEKLEYAEA
KKGGEGVIEVGIEHARKQFIELKEKGVCGVHFYTLNKSYACLKILDGIV
>A0A375EZH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus taiwanensis|TrEMBL
MRAAPTRRATIMQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQ
GTLDAVLEIQREGIEAAPHLSCVGSSRESIRAILQQYREGGIRHIVALRGDMPSGMGEIG
EFRYANELVEFIRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVRAGADSAITQYF
YNADAYFRFVDDVRALGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDD
RESIRAFGLDVVTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A1J5J3N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium CG2_30_59_37|TrEMBL
MKLSDILQQTDGPLFSCEFFPPKTDKGEENLWACLDELKVINPAYISVTYGAGGTTQERT
KGIVTRIQAETGLSPVAHLTCVGSTADDIAALLADYRAAGIENILALRGDPPEGMGRFEA
TAGGFSHATDLISFIHDRQGFSIACATYPEGHPESKGGMMDDIRYLKMKQDLGAACAVTQ
YFFDNEAFFRFQDAADDAGITIPIIPGIMPITNYDQIVRFSAMCGASIPERIHNRMVPVR
DDLDAVKKLGIEMALEQCSGLLGSGVKGLHFYTLNKSEATIAIVQSL
>A0A5B0K9T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudocitrobacter sp. 73|TrEMBL
MSFFHANQREALNQSLAEVQGHINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPHWMSTMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPTL
>A0A2H1J6F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium linens ATCC 9172|TrEMBL
MSQSTLRTLLSTARYEVLPTAGIVERIEEYVAPGREITVTASTGLTLEATLATAEQLQAL
GFRAVPHLAARMIHGRPELTEIVDRLAEAAVDRIFVPAGDATPPAGGYVGAHDLLVDLSS
MAAPFRHIGVSAYPESHPIIPDDVTVQAMWDKRDYATHLVSNLCFDPALVAAWVARVRSR
SIELPLVLGIAGKVELAKLARVATKIGVGESTRFLRKNTATFTRMAKPGGYNPRKFLDKI
GPVLDDPDMGVAGLHIYTFNQIKDTEVWRRKQLAALGGAEEVSTAW
>A0A1F5A2A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium RBG_16_66_30|TrEMBL
MSDKILHVELQTPKRSSEDIEKDLATFEDKYRKVVAAGWIVCITDNPMGLLSYGAMETIE
LLGLPVHPEQLMVHLNTFHPKKELDGILDAFQAVGGRHLLVVSGDGSQRLHRLEPAEVGL
DCTTVTSVELLRYIDREYPGQFTCGVAFNPYEPQDAELAKMKRKVDAGASFIITQPIIGR
DDRLDALLAFGLPVTLDAWMSKKLHLLSECVGHEIPEGTPYDPMENLKELRQNYPDYGLY
LAILGFKTQYPLLQGIWD
>A0A5Y8ST97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A8I1TLW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp|TrEMBL
MITPTALSPELPGRLADALRSGRFAVTAEIAPPRGADLVPVRRAAEHLRGWVDAVNVTDN
AGANVRMSSLAGSLALLEEGVDPVMQMTCRDRNRIALQSDLLSASALGVPNLVLMTGDRP
EQGDHPDAAAVFDLDSGGLMSAARTLRDDATLMSGRAVDPAPRYLLGAVDSPGPSADRFA
QKVDGGAQFVQTQFVFDIATFRGWLGQVRDRGLDTRCGVLAGVGPIRSLRALEFMSSIPG
VVIPEALERRLRGVPSDKVAAEGVAACVETLRELRELPGVAGVHVMVVGDERGVPEILEV
AGLSRTS
>A0A8I2KML3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae|TrEMBL
MALKNEARGRNDIRVSFEFFPPKSEEMEGQLWHAVSQLQDWDPDFVSVTYGAGGTTKAPT
LSTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQ
PHPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQ
FFFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFD
DKPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGFSRRQTKNAGAA
A
>A0A8I2BTJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas manihotis|TrEMBL
MMHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GLEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A850NTR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endobacter medicaginis|TrEMBL
RGAVDDIARRYWDAGVRHIVALRGDPPPGERFSVHPDGYRDAADLVAGLRRIASFEISVA
AYPEVHPEAASPDADLDNLRRKLDAGASRAITQLFFDTDIYLRFIDRCHAKGITAPVVPG
IMPISNFAKARRFVASCGASVPRWLDGLFEGLDTDEGSQHLVGAVVAAEQVRLLQANGVD
EFHFYTLNRAEMSYAIAHLLGARPRSG
>A0A084QBA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stachybotrys chlorohalonata (strain IBT 40285)|TrEMBL
MHIKDMLLEAQSNGQPSFSFEYFPPKTAQGVQNLYDRIDRMYSLGPKFIDITWGAGGRTA
ELTCEMVAQAQTVYGLETCMHLTCTDMDVAQVNDALKRAYEAGCTNILALRGDPPRDQDT
WTATEGGFLYARDLVKHIRETYGNHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDLGASF
IVTQMFYDADNFIRWVGRVRERGIDIPILPGIMPIATYASFIRRANHMQCKVPQSWLDVL
EPVKNDDVAVRELGKQLVAGLCKKLLAAGIIHLHFYTMNLAQATRMVLEELTWAPSAERP
FKQALPWKQSKGLKRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPQSIGDISKIFLRYLDQKLDSLPWSESPLSSEADSIKDDLVA
LNARGFLTINSQPAVDGVKSSHPVHGWGPANGYVYQKAYLELLLHPDLLTEVLNRVSKHP
TLTYYVITKAGELRTNAPGDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAYRLGMDW
AHCYDTNSPSRAVISQIMNSWCLINIVNNDFHDSHLLFEIFNDLEVPNLNTPVTASNGNA
TGAVNGNANGSALKQSAVAGN
>A0A1Q8CR67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola xanthii|TrEMBL
MTSVVDRIPGDRPVFSVEFMPPRDDADEQRLWNAIRSLEGLDPAFVSVTYGAGGSSRDRT
IRTTGRVVKETTLVSMAHLTAVDHSVAELRNVIGWYASLGIRNVLALRGDPPGDVMGEWV
KHPEGLEYAEDLVRLVRELGNFCVGVSAFPYGHPRSADLETDTEFLVRKLRAGADFAIAQ
LFFEADDFLRMRDRVAARGCDALLLPGVMPLTTPRILAKTVELSGAAVPPALAARLDPLA
EDPAAFRAEGMDVTAELCERLLAEGVPGLHFYTFNRAKATKEMVDRLGLLPRRSPTAVG
>A0A0A7KHV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus radiopugnans|TrEMBL
MTRVSIELVPRSRSGLRAELAAVAEHLPGADTINIPDFPRFSTRSWHGCAFARPHHRAIP
HIRAVDLNPREPLPMAAHLDQHGIDEVIVITGDAPGDMNARVYNVDAEAAIRRIRRELPH
LKVYAGLDPYRQSLSREQSYLERKLEAGACGFFTQPFFDLRLMDAYADLLPAGVEVWWGA
TSVTSEGSEGYWRTRNHAVFPRRFEATLEWNRRFACELLTFARERGQHAYFMPIKADVVE
YLGGIV
>A0A626TQB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEIASLIQEE
YQIPSIVHLPCIHSSKEKIIQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A258HSE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium 32-67-11|TrEMBL
MAQALPISFEFFPPKTPEGAVKLRAVRQQLYAQRPEFCSVTYGAGGSTQEGTFATVAEIL
AEGVPAAAHFSCIGATRASVREQLRQLQGMGVQRLVALRGDLPSGYGSGGEFQYASDLVA
FIRAEFGGAFQIEVAAYPEVHPQARSPQADLQALLTKVRAGADSAITQYFFNTDAYFRFV
DEAHALGIEIPIVPGIMPITNSSQLLRFSDACGAEVPRWIRLRLLGYGDDVASIQAFGRE
VVGDLCEQLQLAGVPGLHFYTMNQSAPTLALCARLRQ
>F8C3P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacterium geofontis (strain OPF15)|TrEMBL
MENKTNLQKILESGEFAVTAEIGPPKNADPEIIKEKAKWLKGYVDAVNITDNPRATVKMS
SFAGAIILIKEGIEPIMHITCRDRNRLAIQSDLLGAYALGIRNVLCLTGDHISLGNHPQA
KPVFDLDSIQLLSLVKTLNEGKFFNGDEIKGKKPCFFIGAVENPFADPLEFRPLRLAKKI
KAGAKFIQTQIVYNLERFKKFLNLCEELGILEKVNILAGIMPPKSSKMLKFIKENKVPGI
EVPDELIKRMDSAKDEKEEGINIAVEIIERVKEMSGIKGVHIMAIGWEYIVPEIIKRAKL
YPRPVL
>A0A2E1M892|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MSRIDQMFTERGPTASFEFFPPKAGEAWDALFSGISAFEQLQPSFVSVTYGAGGSTRART
HDLVVRLRSETSLLPMPHLTGRGHTKAEIESILVRYAESGVNNILALRGDPPKDGDSGPG
DFPHAVDLVRFINAFNESGGHPDGGFAIGIAGYPEGHHETPNLLTEMDHFHEKVDAGADF
AISQLFFDNRRFLDWRERCKMAGVHIPLVAGLMPITSAGAMRRMAELAAGTLIPARLLRG
VLDREQDPEMVEAFGVLWATEQSRDLLDHGVAGLHYYTLNRSRAARRVYETLGIRDSRSF
MSGS
>A0A2P7APY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium endophyticum|TrEMBL
MTKIAASIEVAARQAIESQDLPGLFPAGTRVYITDMGTDSVDTLTTAAKRIYDLGYKPVP
HFASRRLSTRVALETRIRRAAEEAGVTDVLVIGGGLERQAGEFSSTMEVLETGLFDKYGI
NEMGVAGHPEGSPEFSEAVALEALRLKKNFGERTGAKLRVVTQFGFDAERFIRYSESLRQ
HGVDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNALSLTALATSHSPEGVVGPIE
QHVLATPASAIKQIHVFPFGGLKKSSEWLVDRGSWNVNTQYANAASN
>A0A085FQU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. LC85|TrEMBL
MNAFRPSRHGTRRPSVSFEFFPPKTPEMETTLWESVRRLEPLGPTFVSVTYGAGGSTRER
THNTVKRMVEETRLKPAAHLTCVSATCAEVDDVIRSYWAAGVRHIVALRGDPAGGLGTVY
EPHPQGYHQTSDLVAGIRRVGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRARGIDIPILPGIVPVQNFKQTASFATKTGASVPQWLADRFEGL
EDDAATRRLVAAAVCAEQVLDLIDRGVSDLHFYTMNKADLVYAICHLVGLKPDRTVQQQA
AAE
>A1SLA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. (strain ATCC BAA-499 / JS614)|TrEMBL
MANQRTRRIGDLVREGERSFSFEFFPPRDEAGEEQLWCAIRELESFRPTFVSVTYGAGGT
TRHSTVRITERIAAETSLTAMAHLTCVGHTRAELETILDTYAEAGIGNVMALRGDPAEGP
RAEWAPTDGGLTYAEELVRLVRGRGDFSVGVAAFPEGHPSATSLDHDADVLVAKARAGAE
FAVTQMFFRASDYFALVQRVRDRGVDLPILPGIMPILNLANIRRQGELIGTEVPAEVVRR
ISAHDGDPMAMRAEGIAIAAELCDELLAGGAPGLHFYTLNRSKATREIFAALNLPV
>A0A1I2A7A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora alba|TrEMBL
MTRVVDRLQPGRTVFSVEFFPPRNDDEEQILWKAVRELEPLDPAYVSVTYGAGGSSRDRT
IRTVGRIAQETTMLPMAHLTGVDHSKDELRHVVGSLASEGIQNILAIRGDPPGDPMGEWI
PHPDGILYADELVRLVRSCGDFSVGVAAFPHMHPRSTDIETETDHLVNKIRAGSDFAVAQ
LFLQPEYFLRLRDRLAARDCHAPLLPGVMPITTPKVLSKFQHLAGVPVPAEVSNVLDPLV
DDPKAFRAAGIELSTKLCERLISEGVPGLHFYSLNRAKATREVVDNLGLAEGVLQPA
>A0A6I1W762|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FSL R10-0071|TrEMBL
VMIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDANSIQAFGEQVISEMCE
RLLDGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A8C7R3G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
MVNNVQRVDDTWRTCTKSNSSGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLVSRSVAETHLPLDWSLGRREIEKKTSNRTYIKQTFQTFD
RMGSGGPLFIDITWHPAGDPGSNKETSSMMIASTAVNYCGLESILHLTCCNQTKEKITGY
LSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKHIRCEFDDYFDICVAGYPTGH
PEAESYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVRDCRAIGITCPILPGIFPIQG
YQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIRNYGIEQTVGMCRVLLESGNVPGLHFY
TLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDW
DDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEELTSEQSVYEVFTSYIKA
QPNCAGHKVMCLPWNDELLAPETNLMMDELDKVNRRGVLTINSQPTINGKPSDDPIVGWG
PPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTW
GIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNL
VDNDFPLDNCLWQVIDDMFELLDNPPEEQPTDPAK
>A0A8C3AHC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclopterus lumpus|TrEMBL
MVNQVQRGDGSLRSCKSDSSGLSNSGGESSKESSRCSTPVLEADRSDRLRDKMRRRTESG
DRWFSLEFFPPRTASGAVNLISRFDRMSAGGPLFIDITWHPAGDPGSDKETSSMMIASTA
INYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEEGFNYAT
DLVKHIRSEFEDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITRVIEPIKDNDAAIRN
YGVQQAVEMCRVLLDSGKVPGLHFYTLNREVAIMEVLRQLGLWIEDPRRSLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSTKDA
LLQMWGAELMNEESVYEVFTCYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNK
RGVLTINSQPNINGKPSADPIAGWGPAGGYVFQKAYLEFFTSSENVTALLEVLKKYEPRV
NYHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWQVIDDMFKMLDAPPGFETQSPF
>A0A315WHN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. AM|TrEMBL
MPLLTDSLQNQPFSIFLEYLPTKHTQPVPSCIAGYPVTMTIADRVRSDDDPEPLVIAQNY
AAEIPKILHFSGKGRDIADFNEFIQAIQEQGYSNVLLLTGDKLKHHQNGQDINFPRTRYL
ESVNAVMQAKKLAPQIKVGVALNPFKYAKAEHDAQYYKLDKKVLAGADYVVTQLGFDLDA
LKEAKQYLENQHSQVDLFACVMPLTAARAEFMVKQKVAGIVLTPHLLQLLKREQSVDAAI
AEQNVYARCALQILICRSWGFAGVHLSACHKPEEQKKLEQALERFQDFSFDQCMRIWNEL
HQLKSGDELKSKPDVFQKKPSTEQVLKYKSMQFMHDSMFDSKIARNVGSKFFNPKLWSGH
FANKLLIKSEYLSKHGVVGCESCGQCRLADTLYICPETCPKGLANGPCGGTTLDRCEFGD
RECIHSIKARLAQQVNQIDVLKKRMIDTVSIESRGTSSWVNWFNPI
>A0A380REQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKVSQVYKKKRSLSFEIFPPKKDAELDNIDETLEVLAELEPDFISVTFGAGGSSNCNRTI
ELAKKIKYDYKIEPVVHLTCLHYDREEIDEFARVLKGEGIENILALRGDPNPNVPAKNDF
RHSSDLISYLKGSDDFCFLGACYPECHPESSGVVSEIKSLKKKVDAGAEVLLSQLFFDNE
IFYRFHEECKIADIDVPVIPGVMPVINAAQIKRMVSLCHASFPARFQKIISRYEDNKEAL
FDAGMSYCLSQIIDLLVSDISGIHLYTMNNPLVARRICEGIKNIV
>A0A5B8LN34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas panacisoli|TrEMBL
MPEARRALATPMFADLAGDAQVSFEFFPPKTEKMEETLWESVQTLAPLGPRFVSVTYGAG
GTTRERTHATVARIAKETAIPAAAHLTCVEATRAEIDAVANDYWDAGVRHIVALRGDPPT
TGAKYATHPGGYENAADLVAGLRKLHPFEISVAAYPECHPDSPDSGHDLDNLKRKMDAGA
TRAITQFFHEADTFFRFRDAAAAAGIDAEIVPGIMPVMNFASVKRMSAMCNTAVPAWMGH
LFEGLDDHPAARQLVAATIAAELSRRLYAGGVRNFHFYTLNRAELSYAICHLLGIRAKPA
LQEKAA
>A0A366H484|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eoetvoesia caeni|TrEMBL
MTTNGKAKAISLEFFPPRDIAAQEKLVRSAKQLLALQPEYVSVTFGAGGSTRSGTVDTVR
MMQNLGFDAAPHLSCIGATRAMLAEILDGYRQQGVRRIVALRGDVPSGMGADRGDLHYAS
DLVRFIREHSGDWFQIEVAAYPEKHPQADTAANDLEHFVAKVNAGANSAITQYFFNADAY
FDFVGRAHAKGVSLPIVPGIMPITNHSQLVRFSDMCGAEIPRWIRQRLAEFGDDKASIKA
FGIDVITRLCQNLLDQGAPGLHFYTLNNADVTMSISKALTR
>A0A3D0Z5I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
DFISVTCGAGGTGKQAKTTDIAYLIQQKYGITSLAHLTCVGSKKDEIYEQLGRLRLLGVE
NILALRGDIPSGDAGLSGDYLYVKQLIADLRGEGFCIGAAAYPEGHIDCESDELNIRHLY
EKQQAGADFFITQLFFDNAVFYRFYEMALAKGINLPIMAGIMPMYSRSQVEKMIFMCAAS
LPSAMIKLLNKYKDSPKDMMKAGVEYASEQISDLLAHGVDGIHFYAMNKPDIARMMAENI
YANR
>A0A4S9L7Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEDDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSLANS
APQNRVVVDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVE
FFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLL
EA
>A0A4S9QZF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRCLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEVTAPQAPQ
IVNGATNGEKHEEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A506U0W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararhizobium mangrovi|TrEMBL
MSILRRSNASLNANRINVSFEFFPPKNGDMETTLFESVTRLAPYHPDFVSVTYGAGGSTR
GPTLNTVRRIHAETDLAAAAHLTCVGSTREEVDAVVREFADVGVKHFVALRGDPQGGIGT
KYAPHPGGYANGAELAAGIRAIDEDFEVSVSAYPEKHPESPDFATDIDLLKRKMDAGATR
AITQFFFDNDAYERYVERARRAGIYIPIVPGILPIHNFGQVAKFANMCGADIPDWLGERF
DGLENDPETRALVATTIAADQVMDLVERGVHDFHFYTMNRAKLVYAICHMLGLRGENREE
AAA
>A0A4T0B5L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVNVTWGAGG
STSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILALRGDPPRS
DEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQSHPEHQHA
TYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGLMPIQSYQ
ILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSGPKGFHFY
TLNLEKAVAHIVERCKLIGAVNNVAVEDHDTPVANGNGDKKAKARRRSSIANSAPQNRVV
IDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIPWSEEGLN
PETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVEFFCSHED
WTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIEAVSFRAW
AEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLLEA
>A0A8C9TKF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scleropages formosus|TrEMBL
INNEKKLKPDDCVRGNIPRPNLTFTLCFLKTMVNQVQRMDGGSQAPKSDSSGASNSGGES
SKESSRCSTPLLDADRADRLREKMKRRIESGDRWFSLEFFPPRTSSGAVNLISRFDRMGS
GGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKDQITAHLAKA
KRLGLKNIMALRGDPLADVWEEEECGFNYATDLVKHIRWEFGDYFDICVAGYPTGHPEAE
SYEADLKYLKEKVDAGADFVITQLFFRAETFLKFVKDCRAVGITCPILPGIFPIQGYQSL
RQLVKLSKLEVPEAMMQVIEPIKDNDAAIRNYGIQQAVDMCKVLLQSGDVPGLHFYTLNR
EVATMEVLKQLGLWNEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQEWDEFP
NGRWGNSSSPAFGELNDYYLFYLKSKSSKEALVKMWGEELMSEESVFEVFTNYITTQPNR
NGHKVMCLPWNDDPLAPETNLLKGELEKVNRRGVLTINSQPNINGKPSSDPIVGWGPPGG
YVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVQGKNITNAPEMQPNAVTWGIFP
GREIVQPTVVDPVSFMYWKDEAFGLWIEQWAKLYEDESPSRMIIQYIHDNYYLVNLVDND
FPLENCLWQVIDDMFDLLDAPPVTVE
>A0A7G6WLL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. NBSH8|TrEMBL
MSPPSLIETHPNLSETAPVALSYELFPPRSPAAAESLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPEELAEIIGDLLDTGVRGILALRGDQPKD
GAPLAAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYANLISRARRAGVTIPIIPGVMPFTSLRRVTRLGELTGVE
PDPELLARLAAADTDSERLRIGVRATVDLANAALEAGAPGIHIYTFNEHQSALEVLDKLA
LPRQSRSVGRRSATLRRQLAS
>A0A0P6YSX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Levilinea saccharolytica|TrEMBL
MLRSQPHPIIGDGAMGTLLNQRGVAFDDCFDKLNLDQPAVVAQIHREYIEAGSQMIQTNT
FSANRYKLARHGLENQTAQINAAAVELARRVILASFKDVLIAGDIGPLGVRLAPFGRVQL
EEARQAFAEQIAALAGAGADVLIIETMTDLYEVVAAIEAARHVAPHLPIIASMTFTRDDR
TLLGDSPAKVAARLQQTGADVIGVNCSGGPSQILRILKAMRQAVPDAAYSVMPNAGWPEQ
MGGRIMYPAAADYFHEYALAFWQSGAHLIGGCCGTTPAHIQTMAQAVQTADPKTWSAAVP
AAAAEIEDNVPDAFQPTQLAQKLAAGRFVIAVEMDPPRGVSTHKLLAGASLLSDAGADVI
NVADSPMARMRMSPWAVCNLLQRKINVETVVHFPTRGRSLLRIQGDLLAAHALDARNVFV
VMGDPTAIGDYPEAMDNYDLVPSGLIKLIKQGFNAGVDHAGTEIGQPTSFFVGCALNLNP
SDPAQEIKNLRRKLSAGADFLLTQPIFNPSVAQAFLQFYADQYGPLPVPLLAGILPLANA
RHAAFLHHEVPGINIPADLMRRMEESGENGAAVGVQIAIELIHQVRAFSQGIYLIPAFNR
FDYAAEIIEAVRAEG
>A0A836MB89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaesserella parasuis HPS10|TrEMBL
MSYAKEIDLLNQSVADLNGKINVSFEFFPPKNEKMETLQWDSIHRLKVLKPKFVSVTYGA
NSGERNRTHSIVKTIQQETGIVAAPHLTGIDATPDELRAIAKDYWDSGIRHIVALRGDEP
AGYAKKPFYASDLVKLLKEVADFEISVAAYPEVHPEAKSAQSDLLYLKQKIDAGASRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMAKMYQGL
DDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGVRPE
>A0A2G2WKD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum baccatum|TrEMBL
MDLSSKSKNWVRRTFVDAGADLIITQLFYNTDIFLKFANDCRQIEINCPIVPGIMPINNY
KGFLRMTGFCKTKKPQRNWQEEAMPSLPVKDIQSGDQFCCQNLNASNCKCFAWLRVRELS
RSIESLGYYSKAACCKTKSEKYVRLISFLGEEVVFVLLSELLWFPFPVLIAVFDHLFSTF
IFKNNGNSSPDGHESPNETNRYVVLSSHRKFKVEISFPNPNAGNCKCSAWSRVGVLSRSI
ESLGYYSKAVCCKASKESMELLSVYATSSRTKTEYLECKFSDLRQEDNVVVQLESQAVCR
GDSFKYLGSMIQGNGEIDEDVSYCIGAG
>A0A6P1D574|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia cyriacigeorgica|TrEMBL
MTFDNVRGRSTPGRPSSTPPIVSGTPSVVQSLRLHSSRAVPFSVEFNPPRDAAGEARLWR
AVRTFERMHPAFVSMTYGAGGSTKDRTVRVTGELAGETTLLPVAHLTAVGHSVAELRSLV
GAYADSGIRNILVLRGDPPGDPLGEWHKHPDGVEYAEELVRIVRDLGDFHVGVASFPQGH
HRSPDLDHDTEFLAAKLRAGAEYSITQMFFDVEHYLRLRDRIVALDPVEGAKPIIPELMP
ITSLRTVKRAEELCGRALPRSVVDRLERAAGSGPEEDTAAVRAAGIEIATEMAQRLIDEG
APCLHFITLNFAKATGEVLTNLGYGVTAAPISA
>A0A8H7W7Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cadophora malorum|TrEMBL
MHIKDMLAEAERSGQPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVSVAQSHHGLETCMHLTCTDMGQEAVDAALKDAYKAGCTNILALRGDPPREKEK
WEATEGGFHYAKDLVKHIRDTYGNHFDIGVAGYPEGCDDQDDPELLLEHLKQKVDAGATF
IVTQMFYDADNFINWMGKVRAKGITIPIVPGIMPINTYASFLRRCNHMGCKIPPDWSAAL
EKVKNDDAAVRNIGTGLVTEMCRKLLAAGIHHLHFYTMNLAQATRMLLEELNLTPSEQRP
LKQALPWRQSLGLGRREEDVRPIFWKNRNKSYVTRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNRKLWGEPKSIKDIAEIFVKYLEGGVESLPWSEAPISSEADSIKSDLIA
LNKRGMLTINSQPAVDGVKSSHPVYGWGPSNGYVYQKAYLELLVSPTLMTQLIARIELDP
DLTYYAVNRAGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRELIENMMDSWYLVNIVHNDFHQTHGLFPLFDGLEVKDIDVPFSTPSNGT
ETNGVNGTAPPPPAGIENVPLTNGNAASAAH
>A0A268F3W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus campinasensis|TrEMBL
MKPDLRQALEKEVLVGDGAMGTYLYQQGFPVGISYEELNLTSPEVIRNVHRQYIEAGARV
IETNTFSANYDKLSKYGLESKVAEINRAGAMIAREAAGEQVYVVGAIGSIRAGRRRDLSS
SELKRYFEQQLDVLLSEGVDGILLETFYDVEEIQLALKEMRRLSSLPVICQFAVEDVART
LDGYTMPEACRILSDEGADVIGFNCRTGPNGIKRALETLEGELNLPASVFPNAGIADYVD
GEYRYGASPSYFGSTAVPFADLGARIIGGCCGTTPAHISEIAKALSGYTPVPLPKRDEAI
PSRIVVQEPGSSDASRGDDLNQSPSLVDLVKERHTVIVELDPPRDLDITKFMKGAEALKK
AGADALTLADNSLAVTRMSNMALGHLVQERVGLRPLIHIACRDRNLIGTQSHMMGFDALG
IDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNEGIAFSGKPLKQKAKFVVGAA
FNPNVKHLDKAVQRLEKKIASGADYIMTQPVYDPELIVKLKEATAHLDIPIFIGIMPLAS
GRNAEYLHNEVPGIQLSDAVRERMAGLEGAEGRAMGVQIGQELLEVAMEHFNGIYLMTPF
MFYEMSVQLMEHVWEKSGRPTPHLFH
>A0A7V4DDI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Caldatribacterium californiense|TrEMBL
MEPFLEFLKGTRVCLCDGAMGTELLRRGYPKDAPLELASITHRDLVRGIHEEYLASGAQL
LETNTFGANALKLSLFGLEEKVEDIVLAGVRLAKEVSRGRAYVLGSVGPLGKPVGKGLGV
EDDRARECYRQQIGALLEGGVDAVLFETMASTHEVALAVEVLRSFDQNIPYLVQFSFFPD
GTTPSGDSLLRVLEFLKSLDACVVGINCGSGPHEAVQILEQFSRHLPGPFSVQPNAGYPQ
IIQGRMVYGAPPEYFASFAGTFVRLGAKILGGCCGTTPEHIRALAQAIGHLEEGTTLEVL
EPERKKAVSEASFPPSTFAEKLGKRFVFTVEITPPKGTNLEGVKEGVRLLKKAGVDAVNI
SDSPMARVRISPIALAHILKEELGVESIVHFTCRDRNLISLQSELLGAAALGVQNILALT
GDPPSVGDHPFARPVFEVTSEGLVLILSRLNSGVDFAGNPLGKATNFTIGVALNLNAQDL
SQEIERLKRKIDNGAHFILTQPIYDPRDLERFFDLFHGSLPPLLGGILPLRSFRHAEFLH
HEVPGIVIPERLRARMAQAEDPKHEGVAIALEVIRGIRDMVAGIYLMPPFERYEMTVAII
EAFRKEDKEDA
>W6EX19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium breve JCM 7019|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQAVGEFNHASDLV
SYIRSVKPDLKVFGACYPEGHYQADTIDQDIENLKIKVDAGATHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A2H0YEC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium CG08_land_8_20_14_0_20_52_24|TrEMBL
MGKKKTVRAAFEAGEFVVTGECGPPKGTDISEMLHHAEGMLGYVNGINVTDNQSSVMRIG
SLPVCKLLVDMGHDPVFQITGRDRNRLAIQSDLLGAHILGIRNVLCLTGDGVQAGDHKDA
KPVFDLESVQILQAVEALNNGKDMAGNDLKGATSLFPGAVVTPESRPIEPQLMKFEKKIR
AGAKFFQTQAVYDIENFLDFMKFARQFDTKIMAGLVLLTSAGMANYMNKFVPGVSVPQNL
IDRMKAAGKEKAIDTGIDIMCEFIKAVRDQCDGVHIMAIGKEHLVPEIVKRAGLA
>A0A077RBP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melanopsichium pennsylvanicum 4|TrEMBL
MTTTSAVAPAAPAAPDPAHITTKIALARSQDAPFWSFEYFPPKTVQGLANLYTRIDRMRS
NLSPSWIHVTWGAGGTTGGKSLELAGRIQKGKLDPDVELVQNELEQINKSGINGVKANDL
WQYGEGTDACDVCLHLTCTNVEKKSLDETLSTAKKLGIKNILALRGDPPRGEEYWVAADD
RFQHATDLVRYIRENHANYFCIGVAGYPEGHADYVDRDVKRDLRFLKAKQDAGAQYIVTQ
LFYDVDQFLSWYNECREIGITIPILPGIMPIQNYQSFRRMTNLCKVRVPQLVLDALEPIK
SDDAAVKEYGVSLSIHMMGRIFLESDMRGFHLCSLNLEKSIERILDGLGWKTDIGAQDES
VARLSAIPTHLHLEATKKQMLSDRTGQNTPKDFKLSTREALERTLARTSSSYQVPETSTW
DEFPNGRYGDSRSPAFGEMDGYGASLKVPPQDALRIWGHPVTPADISTIFASYLEERTSC
IPWCDAPLMAETLQIRDYLLALNRQEGKGWWSVGSQPAVDGAPSTDPTVGFGPPGGFIFQ
KSFVELFMSTHDKDMLVSRIDALGPNAQITYFAGNASGDFASNLDDGEANTVTWAVFPGK
EIVQSTIIERESFEAWREEAFEIWGEWSLLFPKGSASRKYVQGVKEKRWLVTIVHHDYKD
RQGLWRFLAE
>A0A6J4ZPR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter insuavis|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLREILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAASVSADMDHFVAKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHSQLLRFSEMCGAEVPRWIRLRLAELGDDKASIRAF
GVDVITELCQNLLDNGAPGLHFYTLNHAEAPLAVWKELGV
>A0A4Y3T595|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporolactobacillus inulinus|TrEMBL
MGQSILDVLKERILIGDGAMGTLLYSYGIDRCFEELNVSQSEAVRHVHQAYINAGADVIQ
TNSYGANRIKLARYGLEHEVARFNRASVQLAKQAAKPETFVLGTIGGIRGFQKQSVELDT
IRASFREQADALLSEGIDALLLETYYDFDELRDVLQIARTMTDLPIITHVSMQEPGVLQN
GMPVAEALEGLEAQGADVVGTNCRLGPFHMIEALRGIPLPKKAFLSAYPNSSLPDYRDGK
LHYENEPEYFKKYAVEFRNEGVRLLGGCCGTTPVQIKAFKEGISALEPLETKVVTVHPEV
VHVSEAAEPPESALYQKSVNGRSVFVEFDTPRHLNTDHFFRGVQALEAAGADAITMADNS
LASPRISNAAIGKLIKDRYHMPPLVHLTCRDRNLIGLQSHLLGLDVLGLHDLLVITGDPT
KIGDFPGATSVYDVSSMELIKLIKQFNRGISYSGKSLKKPTHFRVAAAFNPNVRNLDRAV
QRLKRKIECGADYFISQPVFDKERIIAISEATRGVSAPIYIGIMPLTSARNAEFLHNEVP
GIRLPDDVRAKMAATSGKEEARQMSFAICRELIDTAMAHFRGIYLITPMGHYSMSVDLVK
YIKKKEREYAALENSENILL
>A0A1X0JAP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides saopaulense|TrEMBL
MTTNPLDHDAPVAELQDPGSIADRLAAVQPGEVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDVD
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEERLLRAAGDGPEENRDEVRKVGVDVTTAMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRITPGTGRG
>A0A177JMW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia cinnamea|TrEMBL
MTQLPDPDPTDGGRHPSIVERIATSTTPRVPFSVEFYPPRDEAAEERLWRAASVFSELGA
AFVSVTYGAGGSTRDRTVRVVERIVRETDLVPIAHLTAVGHTVDELADMIRMYGEVGVSN
ILALRGDPPGDPLGEWTAHPEGLRYAEELVRLIHEVGDFHVGVASFPEGHYRARDLDHDT
EVLVGKLRAGAEYSITQMFWDVEHYLRLRDRAVAADPEQGAKPIIPGLMPVTSLRQVKRM
VELSGCALPDDLAERLRTAAGNGPEENREAVREVGIDLTTRMCERLIAEGVPCLHFNTLN
FSRATREVLTNLSMAPAPGVAASRI
>A0A1R4I0A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. JB380|TrEMBL
MSSQQHPLGISFEFFPPNTDAGRDKLMLVRDELATRNPRFFSVTYGAGGSTQARTRDTVR
TVSQNGITTAPHLSCIGSEKAQLRDLLSQYREEGINSLVALRGDMPSGMGSIGELRYANE
LVEFIRDETGDHFNIAVAAYPESHPQAANLDKDIENFARKMKAGADMAITQYFFTADAYF
NFVDKVRALGVEQPIIPGIMPITNYTKLARFSDSCGAEIPRWMRKQLESYGDDSEAIAKF
GTEAVSRLCQRLLDGGAPGLHFYTLNQAAPVLKVVDNLVG
>A0A0N4Z4M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parastrongyloides trichosuri|TrEMBL
MAPNLEDKKNKEVNFNFEEYSNGLRRNDSSVVSFVDENELTTYTPLIKRINNQIETGVPF
FSLEFFPPKTANGVANFINRLDRFRDGGTFFLDVTWHASSDPANLDKETSSSSIARSVLD
YCRLDTMLHMTCTQYSKEQTMKHIKQCKNIGLRNILALKGDIPVDPNLPENEQPKSKYYA
LDMIKWIKEEYGDYFTIACSGYPLGHPDAKTYRDDLEYLKAKVDAGADFIVTQLFFEVET
FENFVKDCREIGINVPILPGIMPIQGYASIKRIAELSKLLIPQSILDDLEAIKNNDEAVL
KYGIDRAVKMCRRILDNKTAPSLHMYTMNREGPTREILQILGLWKHYQIKSLPWKPHGGH
HPLRCKEDVRPIFWSARPKSYIFRTREWDDFPNGRWGHSSSPAFNDLKEYYMFYLKAGNK
EKELKMYGDKLYSIEDIQQVFVNFLTQKPNENGIKVTSLPWNEEEKGVSFETNLIKDKLI
WANQNGFLTINSQPHVNGAPSSDPIVGWGKQGGYVYQRAYLEFFTTINNVEKLIDIINTN
YNERINYHAIDMTGKYEKFNYNGTNPIALTFGIFAGSEVAQPTVVDPLSFRVWKDEAFDV
FNIWASIYPENSKCREILGHLHDNYILMTLVDNEYVKPTIIYDLLNETITN
>E1QIX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfarculus baarsii (strain ATCC 33931 / DSM 2075 / LMG 7858 / VKM B-1802 / 2st14)|TrEMBL
MKSESNLEKVLAAGHFAVTGELGPPRGADIEAVKKKASHLVGKVDAVNITDNQTAMVRMA
SWATSLVAKQLGLEPNYQMVCRDRNRIAMQSDILGAAALGINTILSLSGDHPSFGDHPQS
SNVHDLDSMQLIQMIKCMRDEGKFMGGAEIKGAPKMFIGAAANPFGDPNELRVMRLAKKI
AAGADFIQTQCIYNMDKFRAYMTKAHDLGLTEKCYILAGLTPLKSGGMAKYMATKVPGME
VPDDLVKRVASAPKEAQAEEGIKILLEQIEQVKEIPGVAGIHLMAIEWEHRVPEITERAG
LLPRPTV
>A6EZ72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter algicola DG893|TrEMBL
METQKQFKRRFSFEFFPPKTDKGWEKLQGVRNTLAEVDPDFFSVTFGAGGSTRDRTVQTV
LDLHKRGVSTAPHLSCVGATRDSIAELLDVYRENGINRIVALRGDMPSGMGAAGELRYAN
ELVSFIREYSGDTFNIEVAAYPEFHPQARTAEDDLKNFARKVDAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCAKLLAAGAPGLHFYTLNQAEPSLSIWKNLGIGEREKIAF
>A0A1Z5YZ42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter cibinongensis|TrEMBL
MSLAHLSVELIPRTEEALRDDTAAVKTLLPAADMLNIPDLMRFPLRSWDAAALLQPVFPS
IIPHVRAIDIAPNAPLPGATQPGLQEILVVHGDPPADLSHRTYPNSTESIIRRYKKEAPH
LRVYAAFDPYRRAPWRELEDVARKKEAGAEGFFTQPVFDHKLFDLCREWLRDETVFWGLS
PVIGPRSRSYWETTNHVVFPKDFSPTLDANIAFAQTVLRELSGSEEKGAVYLMPLRVKLE
HYLPPLQDVLN
>T0IYK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium quisquiliarum P25|TrEMBL
MPIIHPNWDRAAANMVDGYSLEMTAKDVDSLRAAAPALRPETPVAVTFLPGEEFKARIAA
TRLVRDLGFEPMPHFSARRIQSAGEFEDYLSAAVAEAGVKRCFVIAGDPSEPEGPFFDSS
ALISSGAFERAGITAIGIGGHPEGHPNMSRQQCWDVLQDKVADIESRGMAPLIVTQFVFD
ADAVLDWLADLRARGIGAPVRIGVPGPAGIKTLLRFAARCGVGASASVLAKYGISITQLF
GSAGPDKLVDTFARKLGPQHGRVRLHFYPFGGLEKTVAWINDYDRAH
>A0A318JJR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquitalea magnusonii|TrEMBL
MNQQKKTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGHAAAPHLSCIGSTRENISAILNEYRNHGIRHIVALRGDMPSGMVAAGEFRYANELV
EFIRSEHGDHFHIEVAAYPEFHPQAKSAEDDLNNFVRKVKAGANSAMTQYFFNADAYFRF
VDEAQARGVDIPIVPGIMPIANFGQLCRFSDMCGAEVPRWLRQRMQSYYDDTASIRALGL
DVVTELCDRLLANGAPGLHFYTLNQAGLVSTVWQRLGL
>A1CZX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)|TrEMBL
MRWLKFSSITFKYPRYFSHHRGEIRVKMEKITDKIAALPPNENYFSLEFFPPKTQMGFSN
LQARLERMSQALRPLFVTVTWGAGGSTAARSLELAEICQRQLQLTTCLHLTCTNMSRALI
DEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCL
GVAAYPEGHPVDSYQDVQDPVRDLPYLVEKTLAGADFIMTQLTYDIDAYTKFEQMLRNHE
SGAFKTIPIIPGLMPIHSYKILTRTTKLSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLS
DLVEAIKKIPCPGFRGFHFYTLNLEKTVSFIIERCGLIPDYPEDTDAVVDDDYTTAPTGA
QNRSLSRRRASSVNSLPHNRVIVDRLQVPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQ
ISEGQGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVSGAVARRIWGYPVSREDI
SALFRRHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDSKGWWTLASQPAVNG
VRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFQTVLKPLFAKHGHEKLAWFATNVKGEF
ESSLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWR
RVYPRGTPTERLLEEVKNDVWLVCVVGQDFGAGTENGSEEEQQEIKWMWNVLINSQ
>S4YPB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia plymuthica S13|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLDAAPHLTCIDASPAQLREIATDYWNNGIRHIVALRGD
LPPGGGKPDMYATDLVRLLKEVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAA
>B0TS64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella halifaxensis (strain HAW-EB4)|TrEMBL
MGFHHAQHATSLNQSLSELNGDINVSFEFFPPSTPEMEKLLWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETDLVAAPHLTLVDASDEELKELAKHYWNSGIRDIVALRGD
LPEGSPKPTRFANDLVSLLRSVADFDISVAAYPEVHPDASNAQSDLIHLKKKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDAEIVPGILPVTNFNQTKRFAAMTNVSIPSWLHRQFE
GLEDDPTTRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A2V4BR14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium cheongpyeongense|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCHYLGINN
VMALRGDAMKHEQSFVPKDGGNHYAVDLVRQINDLNCGKYLHEVMDIDNRADFCIGVAGY
PEKHLESPSLQSDLRRLKEKVDAGADYVVTQMFFDNAKYFTFVEKAREMGIMVPIIPGIK
PIAVQKHMQILPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A2D8SUF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MAVTQQVSYTKESFDLSFELFPPKTPESEAMLWQTVDELMGFEPTLITCTYGAGGSTHTK
TLEVLDGVLERYPTVAVASHLTCVGRTKDQLREYLRDAKQRNVGSIVALRGDPPQGEAAF
IPVADGLRYAVELVALIKQEFPDFKILVAGYPETHQEAVSPDTDLEHLKEKCDAGGDTVV
TQLFYDNADFFRFRDRCSAVGITKPIIPGLMPVTNFKQIQRIATLCKARLPNRFTRAFEK
AGDDVDAQFEAGVEYASKQAEELISDGAPGMHLYVLNKSPAAVRVLEQVGMTRP
>A0A1I7JYY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. M55|TrEMBL
MKIKDILNSKDVTLSFEVFPPKTDDKYADVEKASAEIAALKPDFMSVTYGAGGGTSKNTA
NISADLQDKYGVTVLSHLTCVSSTKEDVKSMISVYKEKGIENIMALRGDIPKEGRVCYDY
DHATQLISDIKSLDENICIGGACYPEGHVECARQSEDIIHLKEKVDAGCDFLTTQMFFDN
STLYQFLYRIREKGIDVPVLPGIMPITNARQVARSVALSGSTIPQKMKIMVDRFADDPEK
MKEAGIIYACDQIIDLISNGVSHIHVYSMNKPDIAAGIMRNLATIIK
>A0A503E622|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-5-7|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHQVDAVIQEFTDMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHDSEVA
GSAAA
>A0A560BVR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum brasilense|TrEMBL
MTSGIPSVSFEFFPPKTEKMEQSLWQAIQRLAPLSPSFVSVTYGAGGSTRERTHNTVTRI
QKETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPETEGGVGGRYVPHPG
GYAYAADLVAGMKKVADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQFFFD
NDAYFRFLDRCAAAGITVPIVPGILPITNFARAVEFAGKCGAAMPQRFAETFEGLDSDPE
TRQLVAATMAAEQCQALQAQGIKDFHFYTLNRSDLTVAICRMLGVKAKQPAVS
>A0A502TBM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-8-9|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFADMGVKRFVALRGDPAAGVGA
SYHPHPDGYANGAELVGALKNAGDFDISVSAYPEKHPESPDFATDIDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHETEAA
GSAAA
>A0A1Y4HVL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mediterranea sp. An20|TrEMBL
MRVIDLINSREKTAFSFEILPPLKGTGIEKLYRDIDTLREFDPKYINITTHRSEYVYKEL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHVLCSGFTAEDIEYMLLDLQFLGITDL
LVLRGDKAKHEAVFVPEKGGYSHAIELEEQINNFNKGIFVDGSEMTVTKTPFSYGVACYP
EKHEEAPNLEWDLYWLKRKIEAGAEYAVTQLFYDNRRYFDFVKRVREAGITVPIIPGIKP
LKKLSQLSVIPKTFKVDIPEALASEVQKCTTDEQVQQVGVEWCVGQCRELMAQGVPSIHF
YSIGAVDSIRQVAEQIY
>A0A546XJZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium rhizogenes|TrEMBL
MIIKRTMHKLPDISASSIIPASIEASPAHVLGPASLAGLFPQGVRVYLTDTGTASQVKLV
DAARHLRDLGYEPVPHLAARRIPSRAEFEEQVKRLADEAGVSDVLVVGGGVDRPAGPFAS
SMDMLSTGIFDRYGISQIAIAGHPEGSPDFSEETAIAALRLKRDFAQRSDATMRIVTQFG
FDAARFIAWAEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESVVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVNRGSWQTGIADRSAS
PDSVAV
>A0A0P0F4D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum brasilense|TrEMBL
MTSGIPSVSFEFFPPKTEKMEQSLWQAIQRLAPLGPSFVSVTYGAGGSTRERTHNTVTRI
QKETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPETEGGVGGRYVPHPG
GYAYAADLVAGMKKVADFEISVAAYPEAHPEAPSAQFDLDNLKRKVDAGATRAITQFFFD
NDAYFRFLDRCAAAGITVPIVPGILPITNFARAVEFAGKCGAAMPQRFAETFEGLDSDPE
TRQLVAATMAAEQCQALQAQGIKEFHFYTLNRSDLTMAICRMLGVKARQPAVS
>A0A2M7X7W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium CG_4_9_14_3_um_filter_62_6|TrEMBL
MKISLEFFPPKTDEQHAVLARALPKLQAVNPEYVSVTFGAGGSTLSYTPETVRVLKQTWG
FDAAPHISCMGGSREEIRQLLKLYQAMGCKRLVALRGDMPSGMAGFGDFRYANELVEFIR
AETGTEFHIQVGCYPETHPQAGDAFADLKNLKRKIDAGADGAITQYFFNTDAYFRFVDDA
RRFGIAQAIIPGIMPISNFAQLKRFSEVCGAEIPRWIDQRMRGLGDDGDAIRELGADLVA
ALCRRLIAGGAPALHFYTLNRAKATLNVIERLR
>A0A376CLU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium pilosum|TrEMBL
MSARYSSSRPSARLSASAPLDGLDDIHDSPQGAPRPRRLALSFEVIPPRHDADEVKIDNL
LDTLNAYQPDYISVTSSARSQWLTGTAKFIERISANTRARTIAHLACTAGTREELTEWIH
TLLDSGVRGFLALRGDLPEGVTRLDDDHLQHATDLVSLIRTIEQQEAFRLAAGNLAVSVA
CYPSGHAESSGPDEDLDVLLAKQRLGADFAITQLFFDAEDFLRFEQRARLAGVRIPLIPG
IMPMTSLKRAERMGVLSGISVPDRVYKRMRQASSEAEEFEIGMQMTVELARHILDAGTGG
LHIYTHNNAEVTRDILTRIGIEHPGAEH
>A0A1G0BJY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteria bacterium RIFCSPLOWO2_12_FULL_31_7|TrEMBL
MKVTQHIEKANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPSGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGINN
VVALRGDAVKSEIYFKPEKEGHAFASELVSQINDLNNGIYLDADLQNSSQTDFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNKKFFDFVDKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMEVVKAKDNEAVKQIGIEWCIQQSAELVAAGIPVLH
YYSMGKAENIKAIAGKIF
>A0A2V6UIQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MASSNPLRAALAAGRFCYLVELVASRLAREARLLEIASGLARVPGVVAGSITSYAGGAPG
HDPLRIGAAARARGLSPSLHVTCVSLDRHGLRKLLEDAAALGIENVFAMSGDWPTAPVGQ
DRPPAVYDIDAVQLVSLIADLRRAGSPFHVAVAVSPFKYLESDCVYQYLKLEKKARAGAD
YAITQVGWDAEKFRELKRWVDERGLRLPLVGNVYLLGPKAAAKMARGEPPGCWVPPELLA
LVEGERAGADGGLGARLERAARTIAVLRGLGYAGAYIGGTQDPEVIARLIARSDVLAPRW
QEFLAELRFGRPDGFYLYREAPRARRPRREAIPLVLDTLGRLFPVRRETWLRKGLRGIFR
AIDRSRGLARAVERLEFALKQPAFGCQACGNCVLGDLEYVCPMTCPKHERNGPCGGTAHG
RCEVEDKPCIWGAVYARARTAGRLDGLRTYIPPADPGLAGTSSWINYFLERDARPRP
>A0A849D330|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eudoraea sp|TrEMBL
MKVTDHIKAAKGKTLFSFEIIPPVKGHNIRELYDNIDPLMEFNPPFIDVTTSREEYVYID
RNGLLDKKLTRMRPGTVGICASIKHKYNVDTIPHVLCGGFSKEETEYLLIDCHYLGIDNI
MALRGDAMKDEKYFEPSEGGHEYASDLVKQIDNLNHGIYLHEVIETEDCADFCIGVAGYP
EKHMEAPSLMSDLKWLKYKVDLGAKYVVTQMFFDNKKYFDFVKAARDMGIDVPIIPGIKP
IAIKKHLQLLPQVFRIDLPQDLVDAVEACKNNKEVRQVGVDWAIAQSKELKAAGVPVLHY
YSMGKSSNIKAIAEAIF
>A0A7Y3F380|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eudoraea sp|TrEMBL
MKVTEHIENAKGNTLFSFEIIPPVKGRNIKELYDNIDPLMEFNPPFIDVTTSREEYIYID
KNGLLDKKLTRMRPGTVGICASIKHKYDVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNI
MALRGDAMKEEKYFEPSKGGHVYASELVEQIHNLNCGQYLHEVVESDYCADFCIGIAGYP
EKHMEAPSLKSDLKWLKKKVELGAHYVVTQMFFDNKKYFDFVKAAREMGINVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVENCNDNKEVRQVGVEWAIAQSRELKAAGVPVLHY
YSMGKSDNIKAIAEAIF
>A0A2V6R5E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MERRRYQNLLRERLGSGQFVASIEFVTPEASDELEGAIAPLIDLAEHIKADSRFHTIAIT
DRVKSDHDHDPVLVGARVAEACGKMPTVHLSGKDRDAAWTADALRRLEASGLDDLLVVTG
DKVKVEPGGRQVRYYDSVNMVAQARTAGAFHIAAAVSPFKYREEDLMNQYLKMAKKEKAG
ADCFITQVGWDMLKLKELMAYRRRRGFAAPVMGGVMLLTVARARYIRQNKLAGITITDAL
QARLEEEAKQPDKGVGAAYRRLALQIVGLRRLGFAGFQLTGMHQFEKLDKLFRQIDGLER
GLTHEGAWWDAWWLALRGHERAPVVTAPRPYYLFTELAEPGGWSLPSERLTLRDLDPPAS
PNAELERYRSLDRLDRLIFRDGSPGAALLKPIARLVPSGGALDRGLSWLERRVKEPMLGC
QTCGFCRLPYTAYVCPETCPKGLANGPCGGTSENTCEFGDRECMHNRKYRIARDAGRLAE
LEDVLIPDVDATTRGTCSWTSHFRGADPVVVHLSEIRAKGRRA
>A0A2V6Z6F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
TMAFDPSETVADGSGPEHVATTLRDWGADGLGVNCGDGPQIALAIAERMRVVDLPLCVQP
NAGLPRTVDGRLLYMATPEYFDVFARRTIQIGATMVGGCCGTTPEHVRWMAKSGRMLGDQ
RTDVGRARAVKTVQPAIVLAPTPLAERSAFAAKIAAGKFVVSVEVNPAPGLDPSKALAGA
KMLLDSGVDIVNVADAPRAMARMSNIAFCSLLLGRYGIQPILHVCGRDRNLLAQMAHLLG
AHAIGIRNLVIITGDPPKVGDYPEATAVYDLDAIGLLQMASNMNRGVDPAGKPLPGGQTS
FLLATGLEPGAADLDKELARLEKKREAGAELIMTQPIFQTDLLETVLRRIEHLAMPVLVG
VLPLVSYKNAEFLHNEVPGMQIPEVVRERMRKTPGGEAARKEGVKIAREMLFAVRERVQG
AYLMPPLGRYELALEVLDGLKR
>A0A2V7D528|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MTNPLRDALAAGRFCYVVELVASALTREARLLEAASGLARIPAVVAGSVTSYAGGAMGHD
PLRVAAAARARGLTPNIHLTCVSQDRRELAKSLEDMHALSLENVFALTGDYPGAGDQPPV
FDLDSVQLVRLIDERRRAGMPFHVAVAVSPFKYTEADCVYQYVKLEKKIAAGADVAVTQV
GWDARKFAELKRYLDERGLRTPLLGNVYVLGPKTAERMATGRPPGCWVAPKLLAAVQAES
RARDGGRQARLERAARTVAILRGLGYAGAYIGGTHDAANIGWIIRRADELAPRWDALAAE
LGYGATGGFYLPTRTSSTHAPAGAPAASAQSRPRAERVPRVLDWLGRAFPVSRDTRLRRA
LTRVFRWIDRRRPAAVLLERVELAIKKPLFGCQACGNCVLGHLEYVCPQTCPKQLRNGPC
GGTDRGRCEVVPDKPCIWIAVYERACASGDLEALKTYVPPPDRQLQGTSSWINYFLDRDA
RPDRLLVISGADSTRGGHR
>A0A7T9LFZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium canifelinum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNEKVGLEEVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHFTCIGSKKEEIDRVLEDLERNNIENILALRGDYPVDRELELGD
FNYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRK
>A0A2V6UXQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHEFSRRLEAAPLLCDGAMGTLLYARGISLDACFDVLNINDPRVVQSIHADYIAVGADC
IETNTFGANRFKLAVHGLEGRVREINRRGVALARDVRESSGRDVLVLGSIGPLGKYLAPL
GTVTTDEARAAFREQAEALLEGGVDAFIVETMSDLDEAALAVTAVRSITDLPIVAQVAFT
DDGVTFTGRSAAEVARFLKVLPIQALGANCSVGSSTLFEVLEQMQPEAGGLPLAIQPNAG
LPSRIGERLIYLSSPAYMAEYADRMIDAGARLVGGCCGTTPLHIAAMRAVLDQKRPGRGA
GARATLSIRPAAVSESPGLHVARPPTLLGRKLTAREFVVTVELDPPRGHTVEKLVQGAKL
LKERGVDIVDINDGSLGRVRMAVLPTALLVREATGLDINMHFTCRDRNLMGIQGDLLGAH
ALDIRNILAMTGDPPRAGDYANATAVFDVDGVGLIEILRRMNEGLDATGSSIGEPTSFWV
GAALNPAAEDVEREIERFHRKVQAGARWIQTQPIYDLELLERFLARAGGSPVPVLVGILP
LHSARHAEFLHNEVPGITIPDVVRRRLRDAGDGALRAGMEMAQQLVRDVRTRYAGAYLMP
SFGRFEVVAEVLDVLR
>A0A2V6W927|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFSERLAEGALLCDGAMGTVLYARGVPLDACFDVLNLNNPRVVQGVHADYIGAGADA
IETNTFGANRFKLAVHGLESQVREINRRGARLARDVRESAGRDVWVLGSMGPLGKYLEPI
GTVTADEAREAFREQAEALLEGGVDAFVVETFSDLAEMALAVQAIRAVTDLPVIAQMAFT
DEGVTFMGRPPAEVARTVRALGVQALGANCSVGSSTLYDVLERMVPESGGLPLAIQPNAG
LPSRIGERLIYLSSPAYMADYAGRMVEAGARLVGGCCGTTPAHTAAMRETLDRRIPSPRR
VVARAPAPRPAPVETTGIARMLPPTPLARKLEAREFVVTVELDPPRGHTVDKLVQGAKLL
KEKGVEIVDINDGSLGRVRMSVLATALLIRDHTGLDINMHFTCRDRNLMGIQADLLGAHA
LDIRNILAMTGDPPRTGDYANATAVFDVDGVGLIGILRRMNEGLDATGSSIGDPTAFCIG
AALNPAAEDAEREIERMHRKIEAGARWLQTQPVYDLDALEGFLARAGRIPVPVLVGILPL
HSFRHAEFLHNEVPGITVPDAARARLRDAGDGALRAGIDMAQRLVAEVRRRHAGAYLMPS
FGRFEVVAEVLDALH
>A0A5M9NDM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. HV4-5-A1G|TrEMBL
MKISEIMKQKMSFSFEVFPPKMDQPMDNLLDTLEHLYVFNPDFISCTYGAGGTNAGRNVE
VCRAIKKSGRTIPVTHFTCIGNTKKDIKKSLQTYLDMGIDHILALRGDFPKGWEGTRGDF
DYANELVAFIKKNFPEFCIAVAGNPEKHFQADSFEEDIAHLRVKQDAGADYIMTQLCHDV
DQYKWWAEKIRKSGILLPIDVGVMPVLSKDPIIRMTVSNGSAIPRELAEIIARYGDNPED
FKKAGKEYTVKQIYRFINAGINGLHIYSLNRWKDITDILDESGIRNLNEPLE
>A0A3P8LG39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tsukamurella paurometabola|TrEMBL
MPFSVEFMPPRDEEGEARLWRAVRTFERMDPAFVSMTYGAGGSTRDRTVRVTGEIAETTT
LLPVAHLTAVNHSISELRALMGSYADQDVRNVLVLRGDPPGDPMGKWVRHPEGLKYASEV
VELVRELGDFHVGVAAFPEGHHRSPDLETDVRYFANKLRAGADYSITQMFFDVDDYLRLR
DAVVAADPEQGAKPLIPGIMPITSLKSVVRMAELSNAKIPEAMRAELRAAAGDGPEEDRA
AVRAVGIDIATRMGERLIAEGAPALHFCTLNFAKATSEVLENLGMLPVGV
>A0A1F4F7X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_68_20|TrEMBL
MWSLARRTEQRNEARSRLAAVLASGSIEISPKEAHHAPELARLLGENAGVYVHSVPGVTA
EERLASLGELHRAGLDPVPHIAARRITTRERTRELLRRWVGEHGVRRVLLIGGDETPPRG
PYSDSVQYLEEGMLAEAGIRTVGIAGYPDGHPTITPAALEDAFERKLKAARAQGMDVYVV
TQFSFVPERVVELCASLARRAPGVPVYVGVAGPTDPAALMLYAQRCGVGASLRAVRRFGL
GLARLATHTEPAGQLASVARYHQAGGASSNIAGAHLFAFGGAIRTASWMRKAIAEAAAA
>T4VUH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraclostridium bifermentans ATCC 638|TrEMBL
MSLLREALESGKFAITAEMAPPKGIDLSHLVECAKAVKGRVHAVNVTDFQSAVMRTTSLT
TCKLLKDEGLEPVLQVTGRDRNRIAIQGELLSAGVFGIENMLALTGDHTIVGDHPQAKPV
FDLDCVGILQTAQKLSQGTDMVGNQLKGSPEFYLGASVTPRYTPIEIQLLKMKKKINAGA
KFFQTQAVYDIDTMREFKEHTKEMNTKILAGIIPLKSPGMAKFMNENVPGIYVPDELIDR
LRSVGKENWASEGIKIAGELIQQLRDEDLCDGVHIMAIGAEENVPAILDAAKL
>A0A1V3PLQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. C06|TrEMBL
MPAISLEFFPPKTDEQRAQLDQAAQVLKAWRPEYASVTFGAGGSTLSYTSDTVTHLHAEH
GLDVAPHLSCMGGTRAEIRALLDSYKAAGYRRLVALRGDLPSGMASAGDFHYAAELVRFI
REHSGDHFHIEVAAYPEIHPQANDAHADLRHFKAKVDAGANGAITQYFFNPDAYFRFVDD
AHRLGVRVPIVPGIMPIANYSQLQRFSDLCGAEIPRWIAKRMQAHGDDAAAVRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRAKATRAVLEQLD
>A0A4V2FTP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Advenella incenata|TrEMBL
MSSFSDEAFSLEFFPPRDQASRERLVGTAKQLMAMHPRYISVTFGAGGSTRDGTAETVSM
FSQLGCEAAPHLSCIGASRASLIQLLDQYKANGIRRIVALRGDLPSGMGGNDSELPYASE
LVRLIREHSGDWFHVEVAAYPEVHPQADSPEHDLNNFVTKVNAGANSAITQYFFNADAYF
DFVDRAVQRGVSIPIVPGIMPITNHTQLLRFSQMCGAEVPRWIRLRLAQFGDDKASIRAF
GADVVTQLCQKLIDGGVPGIHFYTLNNAEATLAIWKNLRY
>A0A3V4QM42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Kottbus|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7J9VRX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriales bacterium|TrEMBL
MPFKGTEEAVLADVPASIPLTVTVTEAKGISVTVSLAERLTGHGYSVAPHLPARLVSDEG
HLAEVVARLREASIHAVLVIGGDASHPVGRFPDAFSLLRSLENMGRPFKDVAIAGYPEGR
AGIPDQALELALKQKSPYATRIVTQMCFNATTTSEWARDISCAGVELPVHVGLPGPVNRQ
KLIRISSRLGLGQSARFLQKQRSLLWRFLLPGAYGPTKLARSLETSASNARTEIRGLHIF
TFNELHQTEKWRRELLDASQSAAGTWRRGRT
>A0A8G1N5C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pumilus|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEEEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSIEEIKR
SFREQLYILLNEQPDGLLLETYYDMEEAKAVLQIARKETTLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPILENSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHIHAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAAEKRTIIVELDPPKKLNFEKFLVAANELKNAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMAKAGEDKEKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKESNIHVNYH
>A0A497JFB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrothermarchaeota archaeon|TrEMBL
MNSRLMNELKEGKFVFTGELEPRKITDLAEIVEEAKSLKGYVTACNVTDNPGSNACFSSL
VCSYIVQRDAGVETIYQLTCRDRNRLALFSDLLGACALGIKNVLALTGDHPSLGDFPEAK
PVFDLDSAQLVYMIRRMIDKGEDLKGNKIKGEVKLHVGVAVNPNADPLEPELLKFERKIK
VGAEFAQTQVVFDIATIEKFFETLDSLSIPEIPILIGIFPLKSYGVAQFFDKHVPGVKVP
EELMERMKKASEISDKKKRREKYDEINLEYFSELIKEIKKTKARGCHVMAVHYVSMIKAL
IEETRG
>A0A1G0F7G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPHIGHO2_02_FULL_42_13|TrEMBL
MNASKVKVSIEFFPPKSMEKFLDVAKKLSSLHPVFYSVTCGASGTDQAGTVKTVAQLAQN
CNVPVMPHVTCINATRESIKQLLTTYTDLKIKNLMALRGDLPSDMKSTGDFAHANELVKF
VRQETGDHFDIKVAAYPEFHSEAKTSQADLENLKRKIDAGANCAITQFFYNTDAFFHFLE
DCDRLGIDVPIVPGIMPIYNWKRLNDFAQMCGAELPLWLRKRVHDFGDDEKAICDYGVGV
ITGMCEKFIAAGIAQLHFYALNQSDVVLQIINNLSLRVARMERSEMRG
>A0A660N0I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingella sp|TrEMBL
MTAKHLSFEFFPTRTPEGRAKQVDVRAQLAAFSPQFFSCTSGAGGSTREGTLQTVRDILD
EGQIPAAPHLPCIGMLEDEVLSLLSQYKEMGVHRLIALRGDIPSGTGLATEGLRYAHELV
SLVKTQFGSHFHIDVAAYPEYHPQAKNAADDVRHFAAKVKAGADSAITQYFFNADAYFHF
VDEAAKAGADVPIVPGIIPIESFSKLVRFSETCGAEIPRWLRLKLDSFGDDTESVRAFAL
DVVSEMCVRLLQGGAPGLHFYTLNRADLSAEICRRVYGQGA
>A0A443YNG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio sp. S3|TrEMBL
MRVCDLIEGKSPFISLEFFPPKEKDAWPEFFEVVQELKVLEPLFASVTYGAGGGTQDNTL
EIATRMKRDHGIEPLTHLTSVGASAEKLDGFLQSLRAADIENVLALRGDPPRGVENFDFN
SQEFKHATDVIEFICRKYPEMCVGGAAYPEPHFESSSIRSDLEMVHLKVQKGAQFLVTQL
FFDNRLYFDYVERLRVMGSNVPVIPGILPIMSLKSAKFILGLCGAAIPGKFLSALEQAHE
KGGDDAVYELGIDYATKQSQQLIDGGAPGVHLYTLNRAKAVLEIGQNLKF
>A0A520G885|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp|TrEMBL
MRLPLSFEFFPPKTPEGAAKLRAVRQQLYARKPEFCSVTYGAGGSTHEGTFGTVREILGE
GVDAACHFSCIGATRSTVREQLAQLKAMGVKHLVALRGDLPSGYGMGGEFHYASDLVAFI
REETGRDFYIEVACYPEVHPQARSPEADMQAFATKVRAGADSAITQYFFSAEAYFRFVGE
AQKRGLVVPIVPGVMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTDSIKAFGLDVV
TDLCDRLRSGGAPAIHFYTMNQSVATLGVLQRLGWDE
>A0A241V9Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4218|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFQIEVAAYPEMHPQAENFDKDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRIQKQGVDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A841HW11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Povalibacter uvarum|TrEMBL
MLSLSHKLQSSTFTVTTELTPPKGTDLSDLLAKADSLRGYVDGINLTESPRARLAVGPLA
VAKVLKDRGHEPIVQFTTRDRNRIALQADILGAAVLGIENMVFMAGDPPANGDHPQAKPV
FDLSTIDLLQAARSLKEGRDMAGNELKGRPSLLLGATANPGCPDLQREVENVRRKIDAGA
QFLQTQAVYDADALRRFVDALKPDANVLVGIIPLKSSKMANWLNANVPGIAVPEALIAEM
DRVAGDAQAELKTSMDICARIVTEVKSHCAGVHLMAMGWEAHIPGILEASGVRR
>A0A7Y4MRH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcus xanthus|TrEMBL
MKIRNRLNPSDPCFSFEFFPPRTDEGEANLLKALEDLATLQPGFVSVTEGAGGSTRAKTV
ELVLRIKQEAGIEAMAHLTCGGHSPAELRTVLERLSAAKVDNILVLRGDPPKGQTIFEPA
PGGFRYASEMVRFIREEDFNFCLGGACYPEGHVETPSRDDDLRHLKAKVDAGLDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQIQRFTRLCGATVPMRLALQLERVKD
NPEAMAQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRARS
>A0A0N0E9Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. CHD6a|TrEMBL
MGILDSLAQDKILIADGAMGTLLYSYGSDCCFEELNLSQPNQIYNIHQAYLNAGANLIQT
NTYAANYHKLERYGLQDQVKEINSAAVRLAKKAVANHPDAHVVGTIGGIRAIKPEAIPLE
EIKRTFREQLYCLLLEGVDGILLETFYDLEELETVLQIARKETNLPIIAQVSLQEVGYLQ
NRVHITDALNRLESLGADIVGLNCRLGPYHMISTLEEVSIPKTAYLSAYPNASLPSYVDG
KLEYDSDAEYFKETALAFRDQGVRLLGGCCGTTPAHIQAFSQALQDVAPVKEKQVKRKER
TLIIPSKKKEVPTPLFEKAKKERSIIVELDPPRKLNTDKFLAGAQALKDTGIDALTLADN
SLASPRICNTALGSIVKSDIGLRPLIHITCRDRNLIGLQSHLMGLHQLGIHDVLAVTGDP
TKVGDFPGASSVYDVTSFGLINMIKQFNQGVSLSGKELGERSSFSVGAAFNPNVRVIDKA
IERLEKKIDAGADYFISQPVFSEEKLLEVYQATKHIDAPIYIGIMPLTSSRNANFLHHEV
PGIKLTPQVLEAMNRHQNDPHQASVEGLNIAKGLLDAALELFNGIYLITPFMRYELTVEL
ANHAKKYGPSQSSRRVQNV
>E8Q6K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blochmannia vafer (strain BVAF)|TrEMBL
MSMFHATQQEILNRYLVELKENISVSFEFFPPKNAEMEKVLWHSVNKLSKLGPDFVSVTY
GAYSGRREYTNRIIKDIKERTGLIAAPHLTCIDTTPEILRNIAWEYWNNNIRNIVALRGD
QVVQRHSSSMYAVDLVSLLREVGDFDIAVAAYPEVHPEAKTPQSDLINLKKKIDAGASKV
ITQFFFDVEQYLRFRDLCVSVGIEIEIIPGILPIFNFSQLKRFITFTKVKVPNWMCIIFD
GLDQDLDTQKMLGVFIAIDMVKILVKEGVRNFHFYTLNRSDLTYAVCHALGVKNKRHK
>A0A2N1GRU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Choline-02u-1|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A2T5LIR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter sp. OK325|TrEMBL
MPAISFEFFPPKTDEQRAQLDTTVGRLKKHTPDYVSVTFGAGGSTLSYTDETVKRLRAEH
GLSVAPHLSCMGGTRAEIAALLDLYKATDCRRIVALRGDLPSGMASPGDFRYAAELVAFI
REHSGNHFHIEVAAYPETHPQAENALVDLRHFKAKVDAGADGAITQYFFNPDAYFRFVDD
VTRLGVKVPIVPGIMPIANFAQLRRFSEQCGAEIPRWIVKRMQAHGDDAAAVRDLGADVV
AELCQRLLDGGAPGLHFYTINRAKATIGVLERLAAR
>A0A434UJU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.008.03.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFRQVANFSARAGAHVPGWLAERFE
GLDQDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A2S8B2C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis lindanitolerans|TrEMBL
MTSNLDQLAEARRAAASPLFADLAGDIGVSFEFFPPKSEKMEAQLWDTFHTLEPLAPSFV
SVTYGAGGSTRERTHATVARIAATSSVAPAAHLTCVEASRAEIDEVAQAYWDAGVRHIVA
LRGDMPGGAPYRAHPDGYANAIELVAGLKAVAPFDISVAAYPEVHPDADCPQTDLDNLKR
KLDAGGTRAITQFFFSPDAFLRFRDAAAAAGIEAPIIPGILPVSNVSQTRRMAGMCGTQI
PAWMVSLFDGLDDHPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPKVVPATEEAA
>A0A2N1AQ38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. MES3-P3E|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTREVVR
AVGESGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRTETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKVVDNLTD
>A0A0D2GLJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cladophialophora bantiana CBS 173.52|TrEMBL
MASEHDDRLPTLLASLPPSSYYFSLEFFPPKTSSGFSNLQARLSRMAAALRPLFVTVTWG
AGGSTATKSLELAEVCQRQIGLTTVLHLTCTNMKRHMIDEALEGAKEIGIRNILALRGDP
PREEYKDATSADESDGGNGGSGTESNKEFTWAVDLVRYIRRKHGDYFAVGVAGYPEGHAD
ESHPEQGKQSVEHDLPYLAEKVAAGADFIMTQLTYDIEAYATYEKRLREYTDPDGKRLFE
KIPVIPGLMPIQSYQIIKRITKLSHAKLPKKISERIERVKSDDEAVKKVGVDILSELVEE
MKTLPQPEGLPRGFHFYTLNLEKSVSFILERTGLIPSISSEGSVDGKDDDSVSDSDAVVD
DSKQDPPVVVTTGPMNSRNEDGQQPSSLLRRRRSSVNAQPHNRVITDRRSDPRTQSRRPD
SNTDPPGVGPGPNLKLASQHSARDRGTGIPAASPTRRHNLLISEGQGSLGREATWDDFPN
GRWGPSHSPAFGEIDGYGPSLKVTPLMARKLWGYPRSREDVTELFRRHVLGELVGVPWSD
DIDTDLASRNGTSTNGSQNSGALRAETDVIRSELLSLISSQNYWTLASQPAVDGAPSSDP
IFGWGPPGEGFVFQKAFVEFFCGREEWEEKLRPRLMKYGSDVVGWMKTDNEGVFESSELV
ARDQARNKKTSPEDTETENTNPVSTSQLSNQKSATTTSPMNTVNAVTWGVFPSREILTPT
IIEAESFRAWAQEAYAIWHEWKRCFPRGSQEAGFLEKMGRENVLVNVVGQSFRGGHDGGR
GEGARLWTILLGQDDETKP
>A0A7R8L780|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylacidimicrobium sp. AP8|TrEMBL
MANLLEYLSQRLLLGDGALGTYLYSLGLPRRYCLEEANLSRPDLVRRAHADYRRAGAGLL
RTNTTGANRASLGRFGLEERVVEINRRGVELAREAGGGECFLAGSIGPIWLRPWEGSLSP
EERRILYREQITALLEAGCDVIFLETFTELSEATLALSVARELGAPLAAVSLAAFEEGRL
GNGETLGSGLASLRQSGARIVGIGGSCGVLASLHLLEDIEVHPEAFLCAFPNAGKPEFYE
GRLSYSASPEYFAANVERFVAEGVRLLGGDYGTSPLHIAAMAPVLARYRPRLEKPRRQSL
PAIEAARKEEPLKIEEESLLDRYRRKPVAIVEFDSPRTLAMDKFLDGVRALEQAGADALT
LADNSLAILRVSNLAAAVAARRTSRLHTILHLACRDRNLLGIQSELLGFAVLGFRHVLAL
TGDPAKAGDHPGATSVYDLNSLGLIKLIAKLNTGVSAAGRDLKAKTNFVIGCAFNPNSVQ
FDSQVRKLESKIAAGAQYAMTQPVFDAALIRKTAEHLKPLGIPVFVGIMPVLNARNAEFL
HNEVPGISIPESLRERLRHLEGPKATEAGLEAARALAEAVLEQFGGVYLITPFLRYDLTG
RLLEELL
>A0A062SU99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 25977_9|TrEMBL
MKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGKARDIQDFEQFLEQA
QTANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGFRIGVAFNPFKYVE
AERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKAFLTKNNYSQQILACVMPLTLGRA
NFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKHLGFAGIHLSACHKP
EEQMLLESYIEQYRHLELNVLEELWNSLWQVTTGKEFSPEIVRFSRQPTSKQLIKYRQLH
VMHEAMFGSKIAKGVGRFIFKASFWENALIAKLLLKTEVLSKHSLVGCESCGQCRLGDTL
YICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVEQTEILKDKLIPTVSIE
TRGTSSWKNWYLGAEA
>A0A8J5STW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zizania palustris|TrEMBL
MKVIEKIQEAASDGRTVFSFEYFPPKTADGLDNLFERMERMVAHGPNFCDITWGAGGSTA
DLTLEISNRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQNK
FVQVAGGFACALDLVQHIRSKYGDYFGITVAGYPEAHPDAIEGVEGATLEAYSNDLAYLK
RKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALDPIKDNEEAVRAYGIHLGTEMCKKILASGIKILHLYTLNMEKSALGILMNL
GLIEESKVSRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGHGKKLQEEWAVPLKSVEDISERFMNFCQGKLTSSPWSELDGLQAE
TKIIDDQLVEINLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSKEKLD
QLIEKSKAFPSLTYIAVNKDGESSSNVPTNAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWSRGWACLFPDGDSSREILDKVQKSYFLVSLVDNDYINGDLFSAFKEIS
>A0A6I3LJY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myroides albus|TrEMBL
MKVTEHIQKANGKTQFSFEILPPLKGQNIQGIFDSIEPLMEFDPPFIDVTYHREEYEYKE
AGNGLWEKRVVRKRPGTVGICSAIQHRFKLDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKNETYFKPEPKGNKYASELVTQISELNQGIYLDPELENTSKTDFCIGVAGY
PEKHMEAPNFDTDLKYLKQKIDNGAEYIVTQMFFDNSKFFAFVEKCRAIGIDVPIIPGLK
PLATLSQLNLLPQRFKVDLPDDLVAEVLKAKDNAAIREIGIEWCAQQSRELIDAGIPIVH
YYSMGKSDNIKKIIKLATV
>A0A257AH23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon ex4484_205|TrEMBL
MENFLEEILLNKDYILFDGAMGTYLYSRGVPIGSSTMEINLSNPSLIRKIHEEYINAGVD
IIKTNTWSANYSKLSQYNLENKVYEINFRAAEIANEASKGRVLIAASIGPLSKTVEPLGG
MKRNIAYQIFREQLIPLLDAGVDLILLETFQNLDELLLALKVAKEMSNIPVIPQMTFPNG
FSTIYGYSVMDFAKTLENEEVFAIGVNCGLGPWHLLKSIEILRSYTSHHISAQPNAGVPK
FLGDTLYYPTDPLHFSEYGIHYYRLGVRILGGCCGTTQKHIAELYSKLSMKRPKEMVIPK
LKPEVEMKEWTPTLLQSSLKKFFTILVEVDPPRRLSLSKIFRALMKLRAAGVDAINIGDN
PLAKPRINSIVFAHLVMENLGLETVAHFRCRDKNLLAIISDLKSAHILGVRNIVVLTGDP
ISIGEYPHVTPVMDIGATGVIKLMSMMNRGQMPDGSLLGESTSFYIGSVVNPNAKNLMKE
IRLLKKKVKFGARYVLTQPIFQTEKLKRFIKKADLNIHYITGIILLKNEKHAIFLNDEVP
GIEIPDEIITKLEEGYSGMEIAKEVLSKLLGIAQGAYIIPPARNISLAGELVEYVKSITK
RL
>A0A6P1EK27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. 364|TrEMBL
MTAISFEFYPPKTDDQRAQLDRTAAKLKAFAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASDLISFI
RAEHGDAFRIEVGAYPETHPQANDALLDLKHFKTKIDAGADAAITQYFFNADAYFHFVDA
VRALGVTVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDAESVRAFGAEVV
AGLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLKG
>A0A858RPN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteolibacter luteus|TrEMBL
MHISDILAKRRPTFSFEFFPPKTAAGSEDLYRTIVELESFDPSFVSVTYGAGGSTREMTH
DLVLRIKQTTAIPPIPHLTCVGHSEEDISEILRRYADAGVCNILALRGDPPRDWPDYDWS
DCDFRHAADLVAFIKRFNESGAHPDPRGFGIGVAGFPEGHPATPNRLLELDHLKAKIDAG
ADYICTQLFFDNHDFFDFRDRCRLHGINVPIIAGIMPVTSLSGMSRMAELAAGARFPAKL
LRALDRAKGDPAAVEKVGIHYAAQQCAELLDHGVDGIHFYTLNKSKATREIYSSLGLATA
G
>A0A7K2JJ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5910|TrEMBL
MALGTASTRTDRARTVRDILAAGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPTADWVSHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILAAQDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A6A4IKV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gymnopus androsaceus JB14|TrEMBL
MKLIEKIACYNSSHPFYTFEFFPPRTDQGFENLLPRIVRLSNLNPLAISVTWGAGGNTKD
SSLNLAELTQSEYHLDTILHLTCTNMEKGMVDDALRAAKERGIQNILALRGDPPRGKEEW
IPIDPRFQHALDLVTYIRSHPEFSSYFCIGVAGHPDHLKVDAGADFIITQLFYDEDQFIS
WIRKVREKGITIPIMPGIMPIQTYQSFVRLTKLTGTKVPAEVIELNPVQHDDQVIKNYGV
ELTVKMIRRITRETDIAGVHFCTLNLEKSVQRVLESLQWTGSSTQLAPNKLIEGPASGTM
TPTTASNTATLALANINILPTQTEAGSGELNKADSWDDFPNGRWGDFKSPAYGAQGPWGN
NGFHQWGNPQTLDDLTAMFLKYLHSEISTTPFSSDPIFEESKLILTHLQKLTERGWWTVG
SQPAVDGVESSDPVVGWGPTNGYVFQKSFVEFFCSEKDLKAIENKVGEKGEGWVHYYAAN
SKGDCISNVPEDGRNAVTWGVFSGQELIQTTIIERQSFLAWKEEAFGIWADWASFYRPDS
PERKLLERVHDELWLVSVIHHDFKGVEALWTFLIDE
>A0A1I0UZ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetitomaculum ruminis DSM 5522|TrEMBL
MSELQKALESGKFAVTAEMAPPKGYVFDEMLETAQLLKGKVHGINVTDMQSACLKASSIG
LCIKLKQAGLNPILQMTGRDRSRMAIMGDFLAAAAFGIDSMLALTGDHTVVGDCKESKPV
FDLDSVGILQMLTDMEESNKDCGGNDLAEPAPKFYKGASVTPVYDPVFLQINKLRKKVEA
GAKYVQTQGIFDIENLKRFMDEVDKANIDVKIMAGIIPLKAAGMAKFMNANVPGIDVPAD
QIQKLADAAAEGKEKGIKGLPVKVGIELAAEMVAEIKAKNICPGVHIMAIGAEKNVPTIL
EKAGVDISKE
>A0A0S9D1B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Leaf234|TrEMBL
MPPPTYPALSYELYPPRNPAAEESLWTSIRRLEDTRPDFVSVTYGAAGSNRETAIHLLRR
LLTETTLRPLAHLTCVGTSRTELTQIIERLIGGGVRGILALRGDAPEGFEPAAGDVEHAD
DLVRLIREVEGRRTAQLAAGRVSVGVAAYATRHPDSPSVEQDIEVLLAKEEAGADFAITQ
VFFTPSDYTRLVTRARRAGVTIPIIPGVMPLTSTRRLKKLAGLAGVDVDETLWAKLDGAR
TDEERRRVGVTATVGLARAALDDGAPGIHLYTFNEHAAALDVLDALDLERPPEAGLAASL
>A0A1G6DP71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfonatronum thiosulfatophilum|TrEMBL
MKIKDMLQQPDRSRISLEFFPPKDRALWPKFFETVERLRSLNPLFVSVTYGAGGSTQAAT
LDIVSTLKRDFDMEPMAHLTCVGACAEGLREFLDDLVRADVSNIMALRGDPPKGESTFTP
SDDGFQHASDLVGFIAKNYQDFGVGVAGYPEGHPEAVGLEEDLRFLKAKLDLGGDFAVTQ
LFFDNKAYWDFMRKIRDVGIVKPIIPGIMPIFSLKFIQRITSMCGATLPEQFLKDLEQAD
ARGGDAAVQEVGIRHAAQQIQDLLHNGAPGVHLYTMNRSDGCLRIMEQVEQ
>A0A0T5ZRA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium CSP1-6|TrEMBL
MNSLREALAAGRFCYVVELVASRLAREARLLDVAARLASCPGVVAGSVTSYAGGTPGHDP
IRVGTAARARGLTPNIHLTCVSQDRHGLRKTLEDLHALGIENVFAMTGDYPTAPVGQDRP
PAVFDLDSVQLVALISELRRAGMPFHVAVAVSPFKYAEADCLYQYLKLEKKIAAGADVAI
TQLGYDARKFRELTRYLRERGVRTPVLGNVYLLTLRGAEKMAKGEPPGCWVAPELLEAVR
RESVARDGGQAARLERAARMVAVLRGLGYAGAYLGGTHDAGQITWIIQRAEALASRWEEF
AAELTYAPRDGFYLYEGGERGVXRRRHPIPVALDTLGRLFPVQRETWLRRLLRGFFGWVD
RYPLMARGLERVEMAIKGPAFGCQACGNCVLGHMEYVCPQTCPKQMRNGPCGGAHLGRCE
VVDKPCIWGQVYERAKAANRLVDLQAYIPPPDRHLQGSSSWINYFL
>F7KLB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 3_1_57FAA_CT1|TrEMBL
MIKDLFAEKKQLLSFEVFPPKKEDEFANAFAVLDSLAVLQPDFISVTYGAGGSKSKKTVE
IASYIQNQLHIMALAHMTCVGSKKEDIDAVTAQLKEVHVNHVLALRGDRPSYMSDEQFDS
RHFSHAADLITYLKGETDLHIAGACYPEKHYEAADLESDLLHLKEKCDAGAEFLITQLFF
DNEAFYKFLEKSRDAGITLPVCAGIMPITSAKQLGTTVSLSGSAVPKQLADIIATYGDDP
ADMRKAGIDYAIRQILDLKAHHADGIHIYTMNKPKVAQEIVSAIQ
>A0A3S1ZF86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7D.F.Ca.US.004.01.2.1|TrEMBL
IQGDVLGGAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGR
KLTTPPQLFLGAAINPFAPPIDFRPHRLGKKIASGAQFVQSQYCFDVPMFRTYMQKVRDL
GYTEKCFILVGVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIIN
EVKEISGVSGVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDD
ITETQVDMVKTAH
>A0A1X6ZHK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivivax jejudonensis|TrEMBL
MQRPEISLEFFPPKSLEASFRLWDTVQTLAPLGPRFVSVTYGAGGTTRELTRDAVKTIHK
HSGLRTAAHLTCVNATREETLDIARDFWDVGVHDIVALRGDPPKGEDRFTPTDGGFRNSC
ELIEALKAERDFTIRVGAYPDVHPNAGSMQDDVDYLKRKFDAGADEAITQFFFEADTFFR
FRDACAKAGIDKPIVPGIFPVENWKGARRFAEGCGTRIPDWVIDAFEAAERDGRTELLAT
ALCTEMCEALIEGGVDKLHFYTLNKPELTRDVCHAVGVTPETRLENVA
>A0A0K8JDK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionispora sp. 2/2-37|TrEMBL
MHIGELFKKKAKPVVSLEVFPPKPTSPIENVFNTLEGLKALKPSFISVTYGAGGGNSART
LEIADRIKNHCGIEALAHLTCVGLAREEIDNMLDRLEACQVHNVLALRGDPPAGEISFKQ
PANGYRYAQELIGHIKDRRQFCIAAAAYPEGHMECRDMGKSIEYLKMKVDQGVDFLITQL
FFDNNSYYAFRERVLQAGIDCPISIGIMPVLNAAQIERITSLCGARIPEKLKILLDKYRN
STADMEKAGIEYACEQILDLRDHQIDGIHLYTMNKVEQIKTILQQTGITTMV
>A0A5N1L895|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula sp. CBA1131|TrEMBL
MALGTRAVSDSQGVRTLLTSARFELMPFESFDEEITHLPDNATIAITTSPQLGIEKTVEK
TEEAAEMGYDVVPHIAARYVEDQEQLEAIAERLEQAGITDIFVPGGDREEPAGEYESAHD
LLEALAETEYSFAEVGITGYPEGHDFIDDETLAESMAQKAPYATYIVTQLCYDPETVVEW
VEDIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDDEYNIRGVHIYTFNQTPDTERWRHNRLDS
>A0A7W5MR89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. BK369|TrEMBL
MTRYDQLREARTALDTPLFAGLPGDIRVSFEFFPPKTDALMAQLWDVVQTLAPLQPEFVS
VTYGAGGSTRDRTHDTVARIIREARLPAAAHLTCVDASKAEIRAVAEAYWEAGVRHIVAL
RGDMGAPGVPFTPHPDGYANAAELVAGLKTIAPFDISVAAYPECHPDSPSQEADIDNLKR
KLDAGASRAISQFFFEPETFFRFQDKLAAAGIAAPVLPGILPVSNFAQTRKFAAACGAAL
PAWMESLFAGLDTHPASRQLVAATVSAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
RRPHGAAGLENAA
>A0A7V7FYE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas pellis|TrEMBL
MSTSHPLGISFEFFPPNTDVGREKLIGVRDALAARAPRFFSVTYGAGGSTQGRTLSTVCQ
VREAGITTAPHLSCIGSEKAQLRDLLVQYQEEGIDSLVALRGDLPSGMGGIGELRYANEL
VEFIRTETGDHFEIAVAAYPESHPQAPSFERDLENFARKVKAGANLAITQYFFSADAYFH
FVDRARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAGFG
AEVVSRLCQRLLEGGAPGLHFYTLNQADPCLRILDNLSSPLAAR
>A0A852ZJT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolymorpha rutila|TrEMBL
MASGPASTSPRPPRSVRELLTGGDRSFSFEFFPPKTDQGEQQLWRAIRELEPLAPTFVSV
TYGAGGSTRDRTVRIIARIASDTTLTPVAHLTCVGHSRAELRSVIGAYADAGVRNVLALR
GDPEGGPNQPWIRHPEGLDHADELVSLVRELGDFCVGVAAFPEGHPEAVSLDSDAEYLAA
KAAAGADFAVTQFFFDADDYFALRDRAERLSCDMPLIPGIMPVTNVRQIQRFAALSGAAF
PPALAERLLAVEDDPATVRAIGVEVATELCQKLLDGGAPGLHFYTLNRSTATREIYANVV
GPVARVS
>A0A660MIU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cardiobacterium sp|TrEMBL
MSVTRVPLSCEFFPTATPEGAEKLAAVRRDLAVFQFEYFSVTYGAGGSTRDRTMNLVARM
CAENGPPVMPHLTCVASTEAEIRTLLDDYQALGINRLMALRGDMPSGAFENAGFTTATQL
VSYVRQLWGENARICVAAYPEVHPRARTPAEDLHAFREKVMAGATDAVTQYFYNADAYLR
FRDDAQALGVEIPLVPGIMPISNYVQLSRFSDACGAEIPRWLRKRLEALQDDIPALCDFG
ADIVAQMCERLIGEGVPALHFYSMNRADLIREICSRLGWH
>A0A659UK52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.158.01.1.1|TrEMBL
IMRYNGKFLCGRKLTTPPQLFLGAAVNPFAPPFDVRPIHLGKKIAAGAQFVQTQYCFDVP
MFKTFMQKARDLGHTEKVFILCGVGPLASAKTAKWIRSNVPGIHIPDAVIK
>A0A2I0CL74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas pharmacofabricae|TrEMBL
MSTSDRRYSFEFFPTKTDAGHEKLLTVAHQLASYQPDFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDSKAELRELLNTYQANGIQRIVALRGDLPSGMGMASGELRYANE
LVEFIRAETGDHFHIEVAAYPEVHPQARSFEDDLHNFVRKCQAGADSAITQYFFSADCYF
YFVERVRKLGVELPITPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDLQSIQAF
GEQVVSEMCERLLAGGAPGLHFYTLNQAEPSLAIWNNLGLPR
>F9S8G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio ichthyoenteri ATCC 700023|TrEMBL
MGYTHASHIDALNQNVAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKNLKPKFVSVTY
GANSGERDRTHSIIKEIKAETDLVAAPHLTCIDASRQELIQIADDYWANGIESIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFNQASRFAAQNHVKVPGWMAKQFE
GLDDDPTTRQLVGASQALDMVRILSREGVKDFHFYTLNRAEMTYAMCHTLGVRPKVS
>A0A660MEG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cardiobacterium sp|TrEMBL
MCKVPLSCEFFPTATPEGAEKLAAVRRELAYLQCEYYSVTYGAGGSTRDRTMNLVARLVA
ENGPPVMPHLTCVASSEADIRSLLDDYRALGIYRLMALRGDMPSGALENAGFTTAQQLVA
YVRELWGNNARIFVAAYPEVHPRAHTPAADLQAFRDKVAAGATDAVTQYFYNVEAFLRFR
DEALALGIDVPIVPGIMPISNFNQLSRFSDACGAEIPRWLRKRLEALQDDLPALCDYGAD
VVAGICERLIAEGVPALHFYSMNRADLIGELCKRLGWC
>A0A0N8R0Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. coriandricola|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLQLPR
>S2WX00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionimicrobium lymphophilum ACS-093-V-SCH5|TrEMBL
MTTVAQVLNQSNGPTYSFEFFPPKTEQGTSNLMQAVEELEPLKPDFVSVTYGASGTNRDR
TLGVTVELAKRSNLRVIGHITCTAQSVDEVKRAIDAYGEAGIRNILAIRGDMSGGPRVAW
EKHPQGLENATELVELIKSRGDFCVGVGAFPDGHLTSDFELDAQILLAKQQAGAEFAVTQ
LFFEPKHYFDLVERVRNVGVTMPIVPGIMPVSSVKQLGKFVELSGADIPARVAETLLRVP
DDPMMVRVAGSVIASDLCKEMLTGGAPGLHFYTQNRSVATREILAMLRARGY
>A0A6I6EXN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia sp. J780|TrEMBL
MSFFHANQREALNQSLAEISGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPGWMTSMFE
GLDNDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPEASVAV
>A0A844CQB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium RIT693|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRSSEMEQTLWKSIDRLSILKPTFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRGIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPKP
>A0A6M4XG33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. 2692-1|TrEMBL
MGFHSARQVEALNQSLADLSGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPEMYATDLVALLKAEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDDDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQP
>A0A7S3L3E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amphora coffeiformis|TrEMBL
MTKDNNNNNNNNNNLAHLLANPARPVFLLGDVPPGRGTPPGTCQTICDKFQARSRALACD
GYIVYDIQDEPSRDGSERPFPFRPVMDSSPYAALLARSSGRPCLVYKCVTVANFEPWLDT
ARHEHGHNAINLVGRPSSTQNYEGPTMAQAMEICGPQRKNIPFGCVCIAERHTLEAAQAR
QRDYPTEHQNMWRKQQAGAQWFVSQAVYDAEPTIRLLKDYAALCREKGVPPQKVVLTFCP
VSRPKTMQFIKWLGVRVPSQAEAQILAAEKPVDASVEFLCDLLKTILRETAGVDVPLGIS
CESVSIYKAEIDGVHDLFRRLQGILLDSRGTPWKVQWVEVVTIMPRARDNDDNDDYHKNN
DLVPYTNMRRLKESYDNPLIPGLMGVALGGALVAMGVALGGKRN
>K9GSU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenispirillum salinarum AK4|TrEMBL
MTNADTTLDALRAGLPVAEAPVGPIEVSFEFFPPKTEKMQENLWAAIKRLEPLNPKFVSC
TYGAGGSTRERTHETLVDIRNKTNLEPAAHLTCVSATREEVDEVARRYWDAGIRHIVALR
GDSPEGMGEKYVPHPGGYAYAADLVAGLKKVADFEISVAAYPEIHPEAQSAEADIDNLKR
KLDAGATRAITQYFFNPEDFLRFRDRVAAAGITAPLVPGILPVTNFGTVCRFSAACGASV
PEWMHKLFEGLDDDPTTRKLIAATVAIETARKLVSEGAREFHFYTLNRADLTYAICHVLG
VRAQAAAEPAEPAPASA
>A0A4P8ZE53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. oral taxon 171 str. F0337|TrEMBL
MRDNEPTDEPTAAAGSCGDGLSNADPGTVRPLPTVSLELFPPRPGKAASATWGRIDRLLA
TGPDFVSVTYRPTFVSDPAGGNSDGGHEGSPSKPAAGRCDVAPRVRVAQERTNPSECVLA
HVLESSTIPLMAHLTCIGYCKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRADDVAGELR
HADDLVRVIREVEADFFGDGRRHVTIAVAAYPAANDHIEAIEVLAAKQAAGADLAITQVF
YDAADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPESLRSSLGSASGA
TLVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRD
AVDRGYLQATPGRGPSFLRCGTPGAALSSRHPVQPHTTITKENA
>A0A085W310|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyalangium minutum|TrEMBL
MNPSNPCFSFEFFPPKTDEGTANLLRTLEDLAPLEPGFVSVTYGAGGSTRDRTIELVTRI
KQTTGIEAMAHLTCVGHTREELHDVLQKLKEAKVENVLPLRGDPPQGQKEFVPTPGGFRY
ASELVNFVREEDFTFCLGGACYPEGHVETASRDDDLRHLKAKVDAGLDFLITQLFFDNAF
YFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRLCGATVPMRLGLQLERVKDQPESLV
QLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVSALRARS
>A0A2M9VHZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas donghuensis|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLIQYKAAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHIEIAAYPEMHPQARNFEDDLKNFVRKANSGANSAITQYFFNADSYFY
FVERVQQMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A0J6IPW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas weihenstephanensis|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVNVPAAPHLSCVGDSKDDLRSLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGSHFHIEVAAYPEMHPQARNFEDDITNFVRKAHAGADSAITQYFFNADSYFR
FVERVQEAGVTIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVISDMCARLLDGGAPGLHFYTLNQSEPSLAIWNNLKLSR
>A0A2K9MHJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus jeotgali|TrEMBL
MTSPAISFEFFPPRNLDASFRLWDTARALAPLQPGFVSVTYGAGGTTRKLTHEAVTALSN
HYGLNVAAHLTCVDASREETMQIVDDYAAAGVREIVALRGDAPKGQAAWAAHPQGFASSV
ELIEAIAERGDMTIRVGAYPEPHPDSGGSSAADVEFLKRKIDAGATSAITQFFFDADTFF
RFRDACAAAGIDAPILPGILPIQGWAGARKFAASCGTSVPDWAIAAFDAAGKEGEAALAR
DLCTTLCGKLLQGGVDGLHFYTLNKPDLTLAVCADLGLAKPVMAA
>A0A7U3Y755|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain AB0057)|TrEMBL
MSHLSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKVKAGADFIITQLGYDIEAL
KQAKSFLTKHNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQVGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVT
TSKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A1S2Z4N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cicer arietinum|TrEMBL
MKVIDKIRAASADRNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANKMQNIICVETMMHLTCTNMPVDKIDHALETIKSNGIQNVLALRGDPPHGQE
KFVQAEGGFACARDLVEHIRSKYGDYFGITIAGYPEAHPDVIGSDGLAPVEGYQNDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVSDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILTS
LGLIEESKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWSDSGN
PSYGALTDYQFMRPRARDKKLIEEWAVPLRSVEDIYERFRLFCLGKLRTNPWSELDGLQP
ESKIINEQLEKINTKGFLTINSQPAVNGEKSDCPTVGWGGPNGYVYQKAYLEFFCSKEKL
DALVEKSKARPSLTYMAVNKEGIAKSNVGPTDVNAVTWGVFPAKEIIQPTIVDPVSFNVW
KDEAFEIWSRAWASLYPEADASRKLVEQVGGSYFLVSLVDNDYINGDLFGVFGDI
>A0A837LT41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. BIDMC107|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>S5R0J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus lutetiensis 033|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYETYNLTHPEKVLAIHKTYIEAGADVIQT
NTYTAKRHRLDGYGYGEKIKEINQAGVKIARQAAGEDTFVLGTVGALRGLKQCELTLNEI
IKETLEQVRYLLETEEIDGLLFETYYDEEEIIEVLKVVRPLTDLPIITNISIHEAGITEN
GRPLVEIFGKLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVSRKFVTP
MVEEAELIKAVKQSETIVDKVERKVTIIAELDPPKTLDIRKFTKGVKALDEAGVAAITLA
DNSLAKTRICNVSIASLLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIKQLNKGIGYSGASIKKETTFTAAAAFNPNVKNLS
RCGRLIERKIAAGADCFITQPIFNSEIIENLAELTRDYDTPFFVGIMPITSYNNAIFLHN
EVPGIQLSDDFLAKLEAVKDDKEKCQQLALEESKQLIDHALKFFNGIYLITPFMRYDLTV
DLVEYIHQKVEQSHQIIP
>A0A7L5E619|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. F39-2|TrEMBL
MKITEHIANANGKTLFSFELLPPIKGQSLQGIYNAIDPLMEFKPPFIDVTSSREDLVYKE
LPDGSIQKATYRKRPGTVAVCAAIMHKYGVDTVPHLICGGFTKEETEYALIDLQFLGIDN
VLVLRGDARKTDSGFIPTPGGHCYATELLDQVTNMNNGVYLHEYQDSSYKTDFCIGVAAY
PEKHFEAPNLKTDFRYLKKKVENGANFIVTQMFFDVSKYKEFVTLCRENDINVPIIPGLK
PITTAKQLINLPKIFHIDIPEDLSDAVHACKNDKEVKEVGIEWMINQCKELVEFGVPVLH
FYTMGNAEPTKRIAQAIF
>A0A3B8ZVQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MSTFPGRSQAFLAQLQERVIIGDGAMGTLLYSRGIPLDGNFEHLNLVRPELVRQVHADYA
AAGARLLETNTFGANALRLGAIGLEKKVAAINGAGARLAREAAGADGFVAGAVGPLLPPR
GETTELTPEAKSEIFTQQMSALAEGGVDLFLLETFTSLEDLELALAVSATLGLPALAQMA
FLEEGRTRAGVSAEAAVRRLSAAGAAGLGANCGGGPRELLRVLERMARVTALPLSAFPNS
GFPEYHDGRYIYLATPEYFSAVARDMVAAGATLIGGCCGTTPEHIRALSAALAGSRPAPR
PRPVPSAVVPAATATAPPELAGTFLASWGKRTVVTVELDPPRGLDCRKLIAGARALTAAG
ADAISLAENPLARIRLGNIAAARTLHDEVGCATIVHITGRDRNLIGLHSDLMGAHLLGLR
NILAVTGDPVAVGGESGASSVFDLNSVGILQLLAALNGGHNLLGAELDGATSFLCGAAFN
PNLPSMDGQLRRLQKKIAAGARFVQTQPVYDVAILEELVTRTAPLGIPVLVGLLPLVSER
NAEFLHNEVPGITLPPAVRARMRGKHGAAGVSEGMAIARELIEAGRGQVGGWYLMPPFGK
IDLACELMASIRATSPAPLR
>A0A410TT81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halorubrum sp. BOL3-1|TrEMBL
MSVGTQTIERTDGVAALLKDARFELMPFESFEDEIGHLPDDATIAITTSPQLGIDTTVER
TEQAAELGYEVSPHIAARYVRDRDHLDEIAERLTDAGVTDIFVPGGDREEPAGEFESAHG
LLVALDELGHSFEEVGITGYPEGHDFLNAETLSDAMARKSPYATYIVTQLCYDPDTVLEW
IDDIRDDGVDLPIEIGIPGVMNYQRLMEISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
VYKPDDLIDGLAPYAADDYYNIRGIHIYTFNQTPDTESWRNDRLD
>A0A6I5DAP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4982|TrEMBL
MALGTASTRTDRARTVRDILATGKTAYSFEFYAPKTPQGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRATTVKETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVSHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEILPVTSVKMLERLPKLSNALF
PPELKDRILAAKDDPAAVRSLGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A2T0ASI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium thermopalmarium DSM 5974|TrEMBL
MYIKDIFSNKKTVISFEIFPPKKDYSIDTIYETIDKLAPLNPDYISVTYGAGGNTKDRNK
TVEIASIIKNKYNIEALAHLTCISSTRDEVEEVLKLLKDNNIKNILALRGDIPQDPNFKF
PTPLHFKYAVNLIEKIKSRKDFCIGSACYPEGHIECNNFDDDLQNLKKKVDAGADFLITQ
LFFDNNFFYNFREKVDEIGINVPIEVGIMPVTNSRQIKRITSLCGAYVPKKFEKIMDRYI
DKPQALKDAGIAYATEQIIDLLSSGVEGIHIYTMNNPEVARRIVSNIDSVVKAINNNIAV
>A0A1F8NH02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_60_9|TrEMBL
MRIVDRFRAPQKPSFGFEFFPAKTPKAQENLDRTIEKLSALAPDFVTVTFGAGGSTRVGS
RQLAARLKQEKGLEVIAYFAGYGLGPPEISEALNGYSEHGVENILVVRGDPPRDPAFQPH
PESMVYASDLLEYIRPRYSFCLGAAGYPEGHIHAESPDRDADFLKRKVDLGAEYILTNYF
YDNRFFFDYVERCRARGVTVPILPGVMPILTLKLAESIAATCGAGIPEPVR
>A0A1H7AT26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cribrihabitans marinus|TrEMBL
MTAPQISFEFFPPQNLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRDLTREAVQTLHK
SSGLSVAAHLTCVKATREETLAIAEGFADAGVTDIVALRGDPPRGEGAFRPHPGGFANSV
ELIEALAETGRFTIRVGAYPDRHPEAADSQADVDWLKAKMDAGADEAITQFFFEAETFFR
FRDACEKAGIDKPITPGILPIENWKGARKFARSCGAHIPEWVDNAFDKAVRDGREDLLAT
AICTELCSDLIEGGVDRLHFYTLNRPELTRDVCHALGVVPKVALQNVA
>A0A4R9B582|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Hh4|TrEMBL
MEKTSDPACPGRIPFSFELYPPKTESAASALNTTIASLAAAGPDFISVTYGANGSSRRSS
LDVLTHILRTTTVDPMAHLTCVGSSNAEASRLIREFLDAGVRSFLAVRGDPPQGTPEGAA
LLGDLRSAGELVQLIHRVQAEKVPYRETVIPGLPGARNVKTEREKVRIAVAAFPNGHPRS
RSAEQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRARQAGVEFPIIPGIMPVTSPAR
LRRILELSGEDLPSELSIQLEVEPTDQGQREIGIRHATDLARELIAGGAPGLHLYAFNQH
ETVLAVLDGCGLLNPSTPVARLVKESA
>A0A1M7H8R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium suaedae|TrEMBL
MSDAHASRRSRETEAAPINASFEFFPPKTDKMAETLWATVERLAPLRPSFVSVTYGAGGS
TRERTHKTVDRILKETDLAPAAHLTCVGSPREEVDAIIRDYWEMGVRHIVALRGDPLEGI
GEPYRPHPEGYAYASDLVAGIKKIGNFDVCVSGYPERHPESAGWDIEIENLKRKVDAGAD
RIITQYFFDNDLFDEYRERLAKAAITIPVVPGILPIQNFEQTVQFSTKCGTSIPDWLARR
FSGLTEDAETRKLVGAAVACEQVMDLVDKGISDFHFYTMNRADLTYALCRMLGMGGDSSE
QQAA
>A0A1I4BYN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sulfidovorans|TrEMBL
MAKNLTLSCEFFPPKTEKGIANLSAVREQLTPLKPEFFSVTFGAGGSTQDNTMDAVIDIQ
RQHAVTNIDAAPHLSCVGSSAERIRALLDTYRNNDIHRIVALRGDLPSGMQAPGDFRYAN
ELVEFIRKETGDFFTIEVAAYPEVHPQAQSANDDLINFKRKVDAGANSAITQYFYNIDAY
RYFVDNCQKHGIEIPIIPGIMPINNFTQLARFSANCGAEIPRWLRKKLEAFYDDSASMSA
FTVDFLTDFTQQLIELGVPGIHFYTMNKVDPTLTICDRLGLIK
>A0A5A5S7Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa NIES-2521|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSRSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQEVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A1E3NPT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pichia membranifaciens NRRL Y-2026|TrEMBL
MSVKITDKIASLKKDEPFFSLEFFPPKTDSGMRNLYARLGRMSLLGPLFVTVTWGAGGTT
AEKTTDLAVTCQQDLGLTTCMHLTCTNTPKAVIDEALNKAKACGIRNILALRGDPARDTS
VSHGIGEFGHAVDLVSYIRAQYGDYFCIGVAGYPEGHADGSLEELQQDPKKDLPYLVEKV
KAGADFIITQLFFDVSKFIEYEDLVRSQPELENITIIPGLLPINGYNIFQRASKLSHASI
PKALLDQFPPEIQNDDDTVKEIGVDVLVKMIDQIYERKDNHIKGIHFYTLNLEKSIAHII
NKSKYLSKVVAKKEVELEQEESSSDEEIDDSITSAKRAAYADRFNTTNKVISDAKAVHDV
RMTTSPSSQLKKLISISAGHGVLGKDATWDDFPNGRFGDSRSPAYGEIDGYGPSLKVSST
RAYELWGYPTKKEDISKLFINYLLKKLDCLPWSELSLSPETSLIQEELINLNEKFYFTVA
SQPAVNCTTSKDKILGWGPSNGFIYQKAFVEMFVSKKEWNERLLPKLDACGSLVSYYYAD
SKKEFKTNLPSNASNCVTWGVFPNREILQTTIVEEESFKAWTEEAFEIWKEWKLLYPKNS
DSAKLIDSILNDYYLVTVLHHDYPNEAALWELLLED
>A0A2J6J2N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MSLTVATPLPTDVGVSFEFFPPNSEKAETDLWTAIKRLEPLNPEYVSVTYGAGGSTRRRT
HTTVARLNRETGLRPAAHLTCVDADRTEIDEIARQYWQDGVRHIVALRGDPSDGQSIYRP
HPQGYAYAADLIKGLKQVADFEISVAAYPEGHPQAASLDADLDNLKRKIDNGATRAITQF
FFDTEIFLRFHERARSAGITIPIVPGILPVTNFRRVQDFSSLCGTSIPPWMGDLFDGLDN
DPETRKLVAATVAAEQCRVLYTHGIHNFHFYTLNRADLTYAICHILGVRGTAAP
>A0A810NWB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catellatospora sp. IY07-71|TrEMBL
MTLRAPSTMPGPRPTVRELLSSGEPTFSFEFFPPKTADGERLLWQAIRELESLQPSFVSI
TYGAGGSTRGTTVQLTERIATETTLLPLGHLTAVNHSVAELRHVIGHYSDAGVRNVLALR
GDPPGDPQAEWVAHPQGLHYAEDLVRLLKESGDYCVGVAAFPEKHPRSPDLGSDVHHFVR
KCRAGADYAITQFFFDWQDWARLRDAAAGAGCHVPIIPGIMPVTNVSQIERMAQLSGAAF
PADLAERLRAVADDPRAVRAIGVEVATELSVKLLAEGAPGLHFITLNRSTATREVWQRLR
VGATV
>A0A7C2XY63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
MAHALPRPPHPDCVPLFAEARGDIAVSFEFFPPKTEKMADTLWESILTLAPLGPRFVSVT
YGAGGSTRERTHATVERILKETGLTPAAHLTCVGSSRDEVDAIARDYWEMGVRHLVALRG
DPPEAGTRFQAHPQGYGDAAELVAGLKRVAPFDISVACYPECHPEAASPQADIDHLKRKV
DAGADRAITQFFFSAERFFDFRDRVAAAGLDVEIVPGILPVTNVAQARKFAGQCGAAIPA
WMDSLFEGLDERPAARHLVAATVAAELCGQLYSGGVRHFHFYTLNRAELAFAICHLLGVR
AKAAA
>A0A7W5DZA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula rubra|TrEMBL
MTLADQYSSDGCAISFELFPPKTAEGINSLCENVERLMQFNPKYFTCTYGAGGSSQRTTL
DVLERVKKLTKLPVASHLTCVGSNTDQLCEYLQRATDIGVDYIVALRGDPPKGSTEFSVT
DGGLRYANELVDLIRAKFGDLGIAVAGYPEVHQEAVDAKTDLENLKRKVDAGADIVITQL
FYDNADFYRFRDDCVAAGINVPIIPGVLPVTNFKQAQRIAGMCKAAIPASLEAEMTRDDA
PEHQFRVGVEHARKQTIDLLENGVPGIHYYVLNKSDAAVELLDGLQLAGQP
>A0A7C7XH62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pelagibacter sp|TrEMBL
MEYQSTLHKKLHKGSFIFTAETTPPDASSKEVLIEKIKPLKNVADAINVTDSPGAKVHMS
ALTASIILAQQGIEPILQLTVRDRNRLALQGDLVGASALGVNNVLCLSGDDPKGGDQPET
KPVYDIDSLTLVATAEMMRGEKKFPSGRIIDPAPKLFIGGAEVPSKGLPDTKKITNKINK
GVNFFQTQYVFETNKLKDYMKVLEDSGILEKTYFLIGLGPFASAKSAKWMNDNLFGVDVP
DDIIKRLDQAKNAKEESKKICFELIQAFKEIKGVNGIHLMGHKKEEIIAEIIKKSK
>A0A0P7VFU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium HLUCCO07|TrEMBL
MAPKVSFEFFPPQNLEGSFRLWDTIHALAPLDPRFVSVTYGAGGTTRDLTRDAVRTINKA
TGLNVAAHLTCVDATREETLAIADSYAEAGVSEIVALRGDPPKGSGRFVPHPEGFAHSVE
LIEALAAHDKFTIRVGAYPDVHPEAKNAKADIDWLKAKLDAGADEAITQFFFESESFLRF
RDECAKAGIDKAIVPGIVPIENWKGVRNFALRCGASVPAWLDDAFAKAMRDGREDLLATA
LCTELCSELIDEGVDALHFYTMNRPELTRDVCHALGVVPRVQLENVA
>A0A5J6I7B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces coeruleorubidus|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSTDWDTDVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDRVSAAGCDTPIIPEVMPIASARSLERIPSLTNAAF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHRPQA
>A0A554S9P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium piscarium|TrEMBL
MPASDRSLVDALRSDRPTTSFEFFPPKDDEGEAQLWQTIAELEPLDPTFVSVTYGAGGTH
QDRTIRVTERIARESSMKPVGHLTLVGQSTAEIENVLKQYLAAGVDHVLVLRGDPQGGPR
APWERHPEGMDHALELVELAARLGGLTVGVAAFPEGHPDAADRDACADVLVSKAEAGAEF
AITQLFFRASDYVDLVRRLDARGCDLPVIPGIMPILNFAQVSRMAELSGAALPPEVLEQI
EPLADDRAAVRAKGIELATQLCRDVLAAGAPGLHFMTLNRSKATREIFQSLRDESLI
>H3G9J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora ramorum|TrEMBL
MGLALQPTFVTLTWRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNAR
AAGIRNILALRGDPPIGADRWAPVEGGLSNAEDLIKLIREEHGDYFCVACAGYAEVHTES
WNHPDLPPSNEARALDLQRLKAKQDAGADFIITQFFFDVDNMIQWIADCKDAGITIPILP
GYLPIQNYSSFCKFTSWCKTRVPENVLSALDAIKNDDAAVRRYGTQLAVETCERLLAAGV
NSLHFYTMNLATTVTQVLEGLQLLPARNQRELPWQSTLQRSTIEGEQVRPIFWSNRQASY
IARTAAWDEFPNGRWGDRTSPAYGELSEYYLAFKRPKLQRADLWGTPTTEQDVWNVFVRF
IDGHVKQLPWCEQALSLESAAIRENLQWLNSNGFLTINSQPRVNGAPSSDPSVGWGGDNG
VVFQKAYVEFFVAPEKMAHLVKVMRRDYPQLSFHALNRQGDEHRNTPLHSVTAVTWGVFP
GIEIVQPTVVDSDSFAAWKDEAFELWQTQWASAYAEDSRSREVIQHVHDTYFLVNIVDND
YANGEPSCASALTHRPLRVC
>A0A1M3BHN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium 70-9|TrEMBL
MRVDEILANNRPTFSVEFSPPRTPEGEANLLETARQLRELDPDFVSVTYGAGGSTRDGTV
EITRVLKDELGYETMAHLSCVGETTEGLSATLDKIAAAGIESVFALRGDPPRGEGDFVQL
EGGLGNAAELIGFIESGEWEFSLGGACFPEVHPEAPDLATDLAYLKQKVDAGASFLTTQL
FFDNQVYFDFVAAAREIGIEVPILAGVIPVGTFAQTKRICELCEASIPAPLEAAFQAAGD
DPEREFELGVAYAAQQCSELLIAGAPGIHFYALNRAPATRAVLGALKASKPWERTRGDAA
SLAGRIG
>A0A1F0CY69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC22B11|TrEMBL
MSTMIFFMSASNPHGHHEKTSPLPGTPPQPTLQVPVSEAIRGYSPGKIPFSVEFMPPRDD
AAQTRLWNAAEAFHDLGVSFASITYGAGGSTRERTMEVAQQLAAKPLTTLMHLTLVDHSA
DELRVMLQDYARRGMTNVLALRGDPPGDPLGTWQATAGGLNYASDLIELIRNTPECENFD
IGIASFPEGHYRAEDLEQDTQVTLHKLRLGADYSITQMFFDVENYLRLRDRLAAADPIHG
AKPVIPGLMPITSIRSVRRQMELAGGEVPVKILDRLEKAAAGDEVANRDAVREVGIDITT
EMSERLIAEGAPNLHFMTMNNVRATQDVLHNLGMAPAWGPGYGQDMVR
>F7K171|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 2_1_58FAA|TrEMBL
MKIIDRLREDGIHISFEIFPPKTDAGYDKVIRAAEEMAGLKPEFISVTYGAGGGTSKNTA
KIASYIKHDLHVESLAHLTCASSTKDEVRSVIASLKEQGIENILALRGDISEDMVFSERG
SFSLCLSTRRRDPQTWRFLYRSCVLSGRACGE
>A0A0S9PA85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agreia sp. Leaf283|TrEMBL
MESLLTPAAAHAGCPKNMEYGPCGGVDFDGSCEVADFRCVFLGDPLVTWHGAVPSEPDVV
PRSSGATEMMALMDTRPIVVADFPARAMDAESLAECASLLAGPVDAALAGDHGKARVQFS
PSYRASLIRAAGLQVWTGINCRDRNRVAIEGELAGLAHVGVAGVHCVTGDHTLLGSRPDA
APVFDLDSPQVAALARAAGHLVSVGESPTTPPVELRAARLLEKTRAGADVCFVNHCGGVD
AVGRFVRESHDLGVTARFIPCVPMVTDHASAQLLRSFTTLVLPEGYLDRILSAADPREEG
IRAAVELGLELLEIEGVAGVNLSGGAGPGREAEFAIVLAETAQRLAL
>A0A7Y5DJJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionella sp|TrEMBL
MNKPLISFEFFPPQTPEGVEKLTAVRKQLAVLNPEFFSVTFGAGGSTQDRTMETIRLIHA
EGHHAAPHLSCVGSTRDNIRALLLAYKELGINRIVALRGDLPSGMHSIGEFQYANELVSF
IRAQTGEHFHIEVAAYPEFHPQARTAHDDLINFKRKVSAGANSAITQYFYNADAYFRFVE
DSRKLSITAPIVPGIMPIMKFSQLARFSDMCGAEIPRWMRKTLEGYGDNTESVQAFGLDV
VTQLCEKLIAGGAPGLHFYTLNQAGASLEIVKRLGYQ
>A0A6Y0SXM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enteritidis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMKQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7K2T1A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8350|TrEMBL
MALGTASTRTDHARTVRDMLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVTYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A7Y3JXB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionella sp|TrEMBL
MNKPKISFEFFPPQTPEGMEKLVHTHRQLAALNPEFFSVTFGAGGSTQERTLQAVAHIQA
QGSDVAPHLSCVGSTRENIRTLLQSYRAQGVRRIVALRGDLPSGMGSIGEFHYANELVAF
IRAESGDHFHIEVAAYPEVHPQARSARDDLHNFKRKMAAGADSAITQYFYNADGYFYFVE
QCRRLGITKPIVPGIMPIVKFSQLARFSEMCGAEIPRWMRKTLEGYGDDSEAVQAFGLDA
VTALCEKLLAGGAPGLHFYTLNQAAPSMAIWQRLGLAK
>A0A2T4M5S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus auricularis|TrEMBL
MSQFLTQLKDNILVADGAIGTLLYSEGIDTCPEAYNLTHPDKIEKIHRAYIEAGADVIQT
NTYGANFEKLKAFGLEHKIKQIHQAAVAIAKRAAKPETFILGTVGGFRNITQTKLELSTI
QYHTEVQVDTLVEAGVDALLFETYYDLEELTNIVKLTRQKYDIPIIAQLTASNTNYLKDG
QPINEAIQAVIDSGANIVGLNCHHGPHHMVHSFSHIELPKNAYLSCYPNASLLDIENDTI
QYSDNAQYFGQMAQKLINEGVRLIGGCCGTTPEHVHFIKESVKGLKPVSHKNVVPMTQRK
SKGTNNENRNNLTHLVKTRPTIIVELDTPKHLDTTTFFDNVKKLDEEGVDAITLADNALA
TVRIDNLAAASIIKQQYNIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAVTGDPSRM
GNLPGATNVYDVNSKGLTEIALRFNEGINTDGDALKKKTNFNIAAAFDPNVRKLEVAVKR
AEQKIKHGTNYFITQPVYSTDKIKEIYEATKHLDVPFFIGIMPITSYNNALFLHNEVPGI
KLSDEVLERFEALKGDKEQTKAYSLSLSQELIDTVHQYFNGLYLITPFQNVDITLELAQY
SKSNTSTKQEAIS
>A0A7X3H2Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas zhuhanensis|TrEMBL
MSSQEHPLGISFEFFPPGTDAGRDKLMQVCDVLASRNPRFFSVTYGAGGSTQARTREVVR
NIGRSGITTAPHLSCIGSDKGELRELLAQYREEGINSLVALRGDMPSGMGSIGELRYANE
LVKFIREETGDHFEIAVAAYPESHPQAPSFDKDVENFARKMKAGANLAITQYFFTADAYF
HFVDKARALGVEQPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIGDF
GTDVISRLCQRLLDGGAPGLHFYTLNQSKAPLRVLDNLR
>A0A672LCJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus grahami|TrEMBL
MGSCCEKVCGVVCISPGDSSGVSNSGESSKESSRCSTPVLDTDRTDRLRDKMKRRIESGD
HWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATD
LVKHIRCEFDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAETFL
RFVKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSY
GIQQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEAL
LQMWGEELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNRR
GILTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVN
YHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFALLDSPRETQEEGSQL
>A0A672L7K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus grahami|TrEMBL
MWYFHVLSDGAAFTSQSRSSLRSYANSCHYRWQSSKSDSSGVSNSGESSKESSRCSTPVL
DTDRTDRLRDKMKRRIESGDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHP
AGDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALR
GDPIGEDWVEEDGGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDNDLRHLKEK
VDAGAHFIVTQLFFRAETFLRFVKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVP
EEIMQVIEPIKDNDAAIRSYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLG
LWAEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAF
GELTDYYLFYLKSKSPKEALLQMWGEELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWND
DPLAPETNLLKDELEKVNRRGILTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFT
SSENVTALLQVLKKYEPRVNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDP
VSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIE
DMFALLDSPRETQEEGSQL
>A0A6H2F297|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae endosymbiont of Plateumaris braccata|TrEMBL
MKSFDTEQKEYIDKFFSKSFSKCNISFEIFPPADCEIESKFWNFIKILIKFRPKFISITY
RNTSNSYNKTYSIVKKIQKYTNIELAPHITCINVKSNELYNLAKKYWKNGIKHVIALRGD
IININKNINSLIYASDLVYFLKQIANFNITVAAYPEIHPESKNAKEDLINLKRKIDAGAT
RAITQFFFNIETYLIFRDKCISQGINIEIIPGILPINNFIQLKKMIKITNIKIPNFINKM
FQSLNKQDEKICKLLGSFIAIEMIRKLKKEGVNHFHFYTLNKSEIIYAICLYLGIKPNEN
VFNKT
>A0A5P2QK09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas oryzihabitans|TrEMBL
MKPSLSFEFFPCKTEAGHEKLIATARQLASHGPEFFSCTYGAGGSTRDGTYRTVRQLNDE
VGVPTAPHLSCVGDSKAKLRELLQQYREAGINRIVALRGDLPSGMGLSGGGELRYASDLV
AFIREETGDHFHIEVAAYPETHPQARSFTDDVRNFVYKMQAGADRAVTQYFFNADCYFHF
VERVRKLGVEAPVIPGIMPITNYSKLARFSDACGAELPRWLRKQLEAYGDDTQSIQAFGE
EVMTALCERLLEGGAPGVHFYTLNQAEPCIAIWRNLGF
>A0A7L5DRB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma sp. CJU-R4|TrEMBL
MNAQVTKKKTFAELLASDKFIVSAELTPPRHHDLTGFMNAAAIVSEYVDVVQINDHLLSR
ARLSNMVAGLHCKMAGMEPILQFTLRHRNRIALQGDLLGFANLGLNNIIILGGYPCAIGT
DPTAVDATDLGSVEAIERITALTERGEMFNGDIIKPAPSFTVGTIDFPCSPDKMDESFAR
LEQKIAAGAKFIQVQAIFELGPMAQWMQEVVRRGLHKKARFIGAIFPFSGAERLHVLKEI
PGLSIPDHLLHRIESHNSERESLAITLELIDGIRSMEGITGLHIRSIGAEDWVPRIITAA
GLGEQLVY
>A0A5Z4RTU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPPWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>S5R7C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Carsonella ruddii DC|TrEMBL
MKTISFEIFPEKDTKKSIEFIKFLEKKNPNFISITCGKDDNYNFVEIIKKNTDRKIIPHI
VCDTLFLVIIKILKFIKIKIFNFIIITGDNCKNNSYEYIIKIRKLFGHIIKVYSGIYLEE
HKITKNFNKEILFIYKKKKIGINLFLTQFFYNFSIIKYYLNTLKKSGISKNLLPGIFPKK
KIQDVLNFTNKCRIEIPNWVIKNYNFINFKNYYLSNLKNFNHFHFYTFNKIKNVIYYLK
>A0A327MB02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseicella frigidaeris|TrEMBL
MSAQGASGAPRGTLQRWLTGPRVDGLPQLAAQPAPALSFEFFPPRTEALEAQLWSCIRRL
EPLAPRFVSVTYGAGGTTQARTHATVARIVRETRLTPAAHLTCVGAPRAEVDEVARAYWE
AGVRHIVALRGDPPAGMAQYEAHPEGYAYAVDLVAGLRRIAPFEVSVAAYPEIHPTALSA
DHDLDNLKRKIDAGATRAITQYFFDSAIFLRFLDRALAAGITVPIVPGIMPVSNFTQMRK
FSAMCGAGVPDWMGRLFEGLEEDAETRRMVAAVVAAEQVRLLQANGIDEFHFYTLNRPDL
VYAIAHILGARPRRPD
>A0A285RAG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stappia indica|TrEMBL
MSSPERFRRFELDQGTGVSVSFEFFPPKTDKMEASLWSAVQRLEPLGPSFVSVTYGAGGS
TRERTHRTVERMLTETRLAPAAHLTCVGSSRAEVDEIVRAYHDIGVRHIVALRGDPLEGL
GAIYRPHPDGYDYASDLVAGIRRISDDFEVSVSAYPERHPESPDWSAEIDNLKRKVDAGA
TRAITQYFFDNDLFETFMEKVRAAGINIPIVPGILPIVNFETTMVFSAKCGTSIPHWLAR
RFAGLDQDAETRKLVASAVACEQVLDLVDRGVTDFHFYTMNRADLTFAICHMLGLRPAPL
EQQAA
>R6LQQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus comes CAG:19|TrEMBL
MRIIDKIKADGVHISFEVFPPKTDAGFESVLKATDGIAELTPSFISVTYGAGGGTSKNTV
KIASHIKNDLKIPALAHLTCVSSTKEEVHKVIGQLQKEGIENILALRGDIPQDGQFPLPG
QYSHACELIEDIKKMGDFCIGAACYPEGHVEMEHKKDDIRYLKEKVDCGVDFITTQMFFN
NDIFYNFLYRIREQGIMIPVLPGIMPITTKKQLARSCALSGTAVPQRFRAIVDYFGDDPA
AMKQAGIAYATDQIIDLIANGVRNIHVYSMNKPEVAAAIMQNLSEIVK
>F5HHA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)|TrEMBL
MPHLTSLIAAHNGPFHNYEFFPPLTDPGFVNLLDRIRRLTSSPFQAPLAVSVTWGAGGST
AEKSLELAQQVVDMGVEVILHLTCTNMPKDKVDFALRRCKDLGISNILALRGDPPREEEY
AINPTSTPDFFKHADDLVRYIRQTHGDYFCIGVAGYPNPHPDSESEEEDFKWFKAKCDAG
ADFIVTQLFYDVDVFLEWVKTCRARGINQPIIPGIMPIQNYASFRRLVNLTKCPVPDSIT
SDLQPISSDDATVKRYGAELATKMVSQIIESGLVPGVHLCTLNLEKSVRMILDNLGWSAA
SKTSEDEGLVKNKLIEDDGQARKGIPINGKAGTAQSPAKNLSISPSEANQLAQLGLTSTT
LPPAPKTGLSAQGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKEWGVP
VSTSDLSALFTAYLHSDPKHLTTPFCDLPLSPESHMILPHLLALNSANVQHWTVGSQPAV
DAAKSEDEVVGWGPRGGYVFQKAFVEFFVTEDEVNRLKEKVEREGKGLITMYAANRKGDF
KTNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWAEWSLLYPRNTPSRKL
LEGIANEWWLVSLIHHDYKDQGALWRFLLEDLQ
>A0A1E7H0B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium S3730MH5|TrEMBL
MGFRQVLESGKFLVTAEIGPGKGTDVEHLLKDAAIIKDRMDAINVTDLQSSVMRLGSMAF
CHLLTDMGVDPVFQVTCRDRNRLALQSDLLSAWVLGIKNVLALTGDYPTLGDHPRAKPVF
DLDSVSLLDVIARLNSGCDMVGNELKGTPDFFSGAVVNPGADNEAALELQIIKMEKKIEA
GARFFQTQGVYDLDAFEKFMKRIEGFDTKVLGGIILLKSVGMARYMNKNVAGVFVPESLI
KELKGAEDKTQASMEIAVGLIKGMKDLCHGVHIMALGWESKIPHILDEAGV
>A0A379QVE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDASGDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQARKFADMTNVRIPSWMSQMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A419NX04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris|TrEMBL
MSPDPPSRAATIADAYSLEVGAHDMPALTAAAPQIMRGSSMFIPYLPSQNDDARLAAAQR
VRALGFAPVPHLSARRIASRDALQAFVRRAVDEAGVERCLVIAGDAPSAVGPFSDSVSLI
ETGVFERSGIKAIGVAGHPEGHPSMPASAQWDVLERKCRSIAERGMAPLIVTQFAFDADT
VLTWLEALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACASMLSKYGISLGKLFGTA
GPDRFVDRLTAGLSEARGDVSLHFYPFGGIAQSVAWVEQYRHRSARPLAD
>A0A0F4M0Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium asteroides|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLMPDFISVTYGTGRRSDRTATARIAKTIH
TEYGIPAVAHLTAQYADREVIDQALDMFDDAGVAAVLALRGDSVEGREPAGVFEHASDLA
AYIRSRRPNLSIYGACYPETHPEAASPEEDMENLRIKVDSGVDHLVSQLFYDNADFLDFL
DRARAAGIQVPIEAGIMPITNEGQVRHMSEVCKARIPAAVESILDRWGDDRASLREAGII
YASQQIADLVAHGVDGIHLYSMNHSGVTRRIWHNVRHLFRQVGAKEEPVSSQK
>A0A1F9S814|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium GWB2_63_22|TrEMBL
MKLSDRLKSGTKVYSFEFYPPKTAEDTAKLFNTALELKALSPDFVSVTNSSSGVTPYRTV
ALCGVLKAQFGLEIVAHLTCLAHTRTEIAEICSGLKKMDINNVLALRGDPHNVEAGARRS
EYSYAAQLVADLKRDGGFSIGGACYPEKHPEAPSLEADIVRLKEKVDAGAEYLITQLFFD
NACYFKFLDKAAAAGVRVPVLPGLMPITGYKQMQNFTKMMQVGVPDELRRGIERWDGDKD
GMFKFSVEYASRQARALLAGGAPGLHLYTLNRSKAAMAILKNVKTAI
>A0A355TQE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium UBP9_UBA11836|TrEMBL
MIEISELKDFFCTNPPKVSFEFFPPKTPEAEQTLWHTIVRLEPLRPEFVGVTYGAGGSTR
ERTHNIVTRIAKENSLVPTSHLTCAGASRAEIDEIARRYWEAGIRHIVALRGDPPKGSSV
YEPHPQGYRYCCDLVAGLRKIGDFEISVAAFPEGHPESKSLDFDMEVLKRKIDAGATRAI
TQYFFDADDYFRLLDRAEKHHIEIPIVPGIMPVTNAKSLLQFSRTCGAKLPDWIVKLFDG
LDDVPGIRNMLAMQVAAGMLLILRKAGIESFHFFTMNRSELTWALCRMLGIMTKPVSDSE
IAAQSEQRGLI
>A0A419P4P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAAKLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAIDADSDLKYFKAKVDAGADAAITQYFYNADAYFHFRDA
AQRLGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDADAVRVFGAEVV
AALCERLIAGGVPALHFYTLNLAKPTTQVLQLLGR
>A0A6N9P6Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MMDIRDELNRGVLLFDGSMGTYYASLYPDGERVESANRQHPGRVRAIHTAYLEAGARALK
TNTFSPFDVEGETLAQTLEAGYTLACEAAKPYGAAVFADLGPSAQSIEDCLRAADCFLSL
GAENFLFETFSDFAALDRVASYIKSKRPSAFVLTSFASNPDGVTRHGLSAAALLRQADAC
AEIDAAGFNCMSGPSHLLRLTESLQTLPRLLSVMPNAGYPAIVRGRTVYEGTPGYFAERM
AALTAAGAKILGGCCGTTPEFIRETRKALDTQRPAPKSVIASVQSRITLTARKEGRNRLA
EKLDAGQRIAAVELDPPVDADVSGFLTGARRLVEAGADTITIADCPIARPRVDSCMLAAK
LRRELGIDPIPHMTCRDRNVNATRALLLGLSIEEVHNVLVVTGDPVPSAERDEVKSVFSF
HSAILADYIRKLGSENAVVPFRVFGALNVNAANFDAELKKALRKRDAGVCGFLTQPVMSG
QAFENLQRAHEEMPEMKLLGGVIPVVSERNALFMNNEVSGIEVPANIVRRYHGLGREAAE
ALAVELSVGFARRMEPFTAGWYFMTPFQRVGLIERILHALRG
>A0A7C6G3Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MNHNHITDNALVLYDGAMGTYYRWLYREDDSLLEEVNLSNPDRIKEIHQAYIKAGAVRIK
TNTFAAFPLMLKQNADQVKQMVLAAWHLANKAIYELKAQETVKVVADIGPFFVLQSGLAD
DFQTESQQAYLDLVKIFIDVGAEEYLFETQEQLTDLIPAIKLIKSYNPNAKITVSFSVNQ
NGFTRTGLRLKELLAQAEQTDEITFTGLNCTLGPTQLGQVFAEHAESSKFCFFGPNSGLP
ERDLGRGRGGMEAKYFAESCQKAWANGAYQLGGCCGTNPLDIRALFDLFKAQKPVLSKRF
DSKLELKVSEQSGSETEISDKPESGKAEIEGIKITEKTWYEKLLTGEQIVAIEYDTPTKA
NVETYLEKVAQLKAAGMDLMTIADNPNGQTRIDSALMAARIKRELDVEVLPHFTCRDRNI
FAIHSLLLGLATCDVHQILAVTGDPIPLENRNQIKSVFNVNSQSLLRYISQLNQDMPRPF
ILSAALNVNVPRFDMELKKAKRKVESGAQVFLTQPIFTERGKENLMLAKQELGDQVKFLA
GIMPLVSEKNALFMKYEMSGIDVPDEIIKRYADRDRDQAEKLALEISREIMADLQQVTDG
FYLITPFQRTHLTAQLCREWKVKKN
>A0A7C7DYQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKISELYGQKKQSLSFEIFPPKPHLPLDTLFRSIEGFKKLSPDFISVTYGAGGS
>A0A7X8LW26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKTADLFKKKTVFSFEVFPPKKTSSIDTIYSTVEQLKELKPDFISVTYGAGGSENNKKTL
DIASNIKNHYGIESVAHLTCIYLTKQDVLKMLGEFNAAGIKNIMALRGDINPDYTPKDDF
KYASDLVSFIKENGDFGVLGGCYPEGHFESASIVDDIHNLKKKVDAGVSHLVTQLFFDNA
HFYRFRERAAIAGINVPIEAGIMPVTNKKQIERMVTLCKVELPHKFLTMMNRYENSPEAM
RDAGIAYAIDQIVDLITQGVDGIHLYTMNNPYIAHRIHEAVRSLIEYKG
>L9WU79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronococcus jeotgali DSM 18795|TrEMBL
MSSDIQSMPTAEGMVELLEKPRFELMPFESIDEQLGHLPEGSEIAITTSPTLGLEATIEW
SERASERGYEIVPHVAARYVEDRGHLEEIARRLTDAGVTDIFVPGGDREEPAGEFESALD
LLVALEDLPYEFAEVGITGYPEGHAFLDDETLAEAMARKEPYATYVVTQLCYDPDAVLEW
IDEIRTRGVELPVEIGIPGVMKYQRLLGISKKVGVGDSVRFLQKTSGIVGFLRQLVGSRG
TYSPDTLLEGLAPYATDPYYDIRGVHIYAFNQVPDLETWRVETLEKHR
>A0A7X8HZN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MRITEIISGEKPSLSFEVFPPKTSDKFDTVLSATKEIAILDPPFMSVTYGAGGGTSKYTA
TICKALKDQGVTPIAHLTCVSSDKKFIQTELEVLRENNITNILALRGDIPDGLDINKASY
RHASELMQDISEFGGFCIGGACYPEGHPESSNSKADLEGLKYKIDSGCEYLTTQMFFDNN
ILYNFLYRLYRENINVPVIAGIMPVTSASQMKRIISISGAALPQRFVRIVDRYGDNPAAM
KQAGIAYATDQIIDLFANGINAVHVYSMNKPDVAAAIQNNVSEIIK
>A0A3R6TJ35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM05-6BH|TrEMBL
MLYQGNIRDYLSKQPLLFDGAMGTYLADKYIQFGGESCEKWNLRYPERIKQIHKEYIDAG
AVAIKTNTFAANAGDHFTAEEVGKVIAAGTQIAREAIEESAGEQILFGDIGPVVIGDEND
AAERYRLPVDCFLEQGVRHFLFETLDNIEGLDEITEYIKQKQPEAFIIVSFAVSPEGLTR
SGCYGRSLYQKMMKVSSIDALGFNCISGPKHLLDLMYKLSREKNTKYISIMPNAGYPAVL
DNRTYYEAHHYYYAKEMYQIAKQGASIIGGCCGTDPSFISEIAKTLQQSPLPGRKTYSAD
GSGRSVHSVVENRQTEQSIPVANDGQEVKNYAGKDNLCNTFAAKLACGEKVLVVELDPPV
TPEIDFFMEGAVKYQQAGVDAIDIADCPVAKARIDSSILACKVMRELGLTAIPHMTCRDR
NINATKALLLGLNVEGVNNVLTVTGDPVPAAERGLVKTMFSYNSAVLANHIRTLNEQIFQ
NNPFMISGALNVNAVNFDSQIIHAKRKISQGIDVLFTQPVLTERALNNLKRAREELDVKI
LGGIMPVVSYRNACFMNSEMAGIDVDPRIIEMYQDKDRAQGEELAEQISAQVAQEIAPYV
DGFYLITPFKRVELILRIIKQIRGLLDR
>A0A1B7KPK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parageobacillus thermoglucosidasius|TrEMBL
MGLLEDLQERIVIADGAMGTLLYSHGVDRCFEELNLSKPEDILHIHEAYIAAGAEVIQTN
TYGANYVKLARYGLEDEVPSINRAAVRLAKQAAKNKAYVLGTIGGLRSINKSAVSIDEIK
RTFREQLFVLLNEDVDGLLLETYYDLEELKTVLVIARKETDKPIIAHVTLHEVGVLQDGT
PLAEALAQLEQLGADVVGLNCRLGPYHMIRSLEEVPLPSKAFLSAYPNASLPDYRDGRLV
YETNTDYFKETALAFREQGVRLIGGCCGTTPKHIEAMAIALTDRTPVQTKTVKQRHISVS
ISSDEPNAAPPLQDIVRKRRSVIVELDPPKKLGIAKFLEGAKALKEANIDALTLADNSLA
TPRISNMALGTIVKEQLGIRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVER
LEKKIQCGAHYFITQPLYSEQKIEEVYEATKHLETPIYIGIMPLVSARNADFLHHEVPGI
TLSDEIRSRMASCANDPVQSAREGIAIAKSLIDAAFDLFNGIYLITPFLRYEMTVELVRY
IHEKEQAAQEREVLHG
>A0A220WMD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. vignicola|TrEMBL
MIPTDTPSGASTITDAYSLEVSVKDIGALTNAAPGILPGCAMFIPYLPGQTEAARLAAAQ
MVRRLGFEPVPHLSARRIGSLKELQAFIARLVGEADVTGCLVIAGDPSTPKGPFADSVSL
IETGVFERSGIRTIGVAGHPQGHPIMRTTEQWDVLQRKCRSIQERGMAPLIVTQFGFDAD
IVMTWLEALRARGMTHPVRVGVPGPASVGTLARYAASCGVGACASVLSNYGVSIGKLFGN
AGPDRFVDHLVSRLTEAHGDVRLHLYPFGGIAQSVEWVAHYRSCKASQDRVSSVAAD
>A0A5F2B089|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira barantonii|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTQEGDAKLMETVKELSGLNPDFVTVTYGAGGSTRDK
TAQILSEISKKYSFSTVSHFTCVGANREQILETLKGIRSSGITNLMALRGDPPKGEGEFK
KTEGGFGNATELISFIRSEKLDFCIGGGCYPEKHPNANSLEEDVRHLKLKVDAGTDFLVS
QLFFMNSIFEKFLNQVRKVGITIPVIPGIMPITSFSQIERFRSLAGCEFPSSLIADLQEV
EHRPEEFYRRSLNFTVKQCRELLAMGAPGIHLYTLNQSHASYDIVRELKG
>B2T6X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN)|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLVTLKPKFMSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHVSCIGSSKESLRAILTEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLDNFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCGRLIDVKVPGLHFYTLNGAAATKAICERLAV
>A0A1Q4FBW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium 63-13|TrEMBL
MSISFEFFPPKTDEQRQGLENAVRQLKSVAPDYVSVTFGAGGSTLNYTVEAVRNLRQQHG
LDAAPHLSCMGGSRAEIRALIAEYRALGIRRIVALRGDLPSGMASIGDLRYASELVEFIR
AESGEHFHIEVACYPEVHPQASDALADLSHFKRKIDAGANGAITQYFYNADGYFRFVDAV
RALGVEVPIVPGIMPIANFSQLRRFSEMCGAEIPRWLAKRLGAFGDDAAAIREFSSDVVA
ELCRKLLAGGAPGLHFYTLNRAKPTLSILERIER
>A0A8F7BVU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. D764|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHPSAMDLVDQINNLGRGKYLHNEEQACDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREIGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>R6FUH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:221|TrEMBL
MRINNLFNEKKMVFSLEVFPPKVTSSIETIYKMLEELKGVNPDFISVTYGAGGAATSNRT
LEIASLIKNKYNMEPVAHLTCIDAKEDEIKEILRNLKNEGIENILALRGDGNPDTAGRSN
DFKYASDLIQFIKKTDDFNISGACYPEGHIDCRNLDKDIENLKIKQEAGASHFISQLFLD
NEYFYSFMDKTIEKGITVPIQAGIMPVINKKQIERITTLCGSNVPKKFMKIMDRYEHDPI
ALRDAGIAYAVEQIVDLISSDVKGIHLYSMNNAYVAKSINNSIESIIKSVNK
>A0A3M8DN21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus nitrificans|TrEMBL
MTTGKKDLREYLQDHLLVGDGAMATQLHRLGVPLGVSFEELSLSNPKLVQEVHDSYYAAG
ARLLETNTYSANRDSLSRYGLEHRVARINRLAVKIARESARDDAYVAGSIGSILAGRVRK
KVLDEYRDQYEEQAIALLHAGVDGIILETFLDLEELLMALEVIRPLTDAPLIAQLATLEV
GRTRDGYSLTDAFGQLKQAGADIVGLNCRLGPAEILRSFEHTQVPHGALLSAFPNAGRLG
LTDGEYAYKSTPDYFGQSALRLREQGIRLIGGCCGTTPEHVKAMADALESLEPQERINPT
IVPGDRPQVTVQSVRDQSKPSIVERVKTETTVIVEFDPPRDLDAESFLDGCCELHRAGAD
AITLADNSLATVRMSNMALGALMKSRHGIDPLLHIACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGATSVFDVTSFDLIRMVKQLNEGVSFAGRPLKQKAQFIVGAAFNPN
VRQMDAAIARLEKKVEAGADYIMTQPVYDAESIKQVYEATKHIGIPVFIGIMPLTSLRNA
EFLHNEVPGIKLSSEALERMRAVEQGEAARQEGIKMAKELLDTAVQYFKGIYLITPFHYS
SMAAELVQYVRQQSALVKTATH
>A0A6J1M8W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila hydei|TrEMBL
MCVNVTRNQTAAALLLRNVTTLAQNRVAQLIGRNQLLACSARVNIELAMHTLEPNGTRSF
AGDLSKRLLDCFQFTPEQLAGRGEQPYISDLVSDKVARGEFFYGIEITAQSGGKLTCVDF
NRFQPILPTLISIVWLCHYWDVTPMERVDSLQMIRHLEQYIPAMPHFSIYMMTKERIDEF
LALNFKNLLAVRGNRWDDNQFYTYGYQLVEHARRARKSNLTIAIPGYPLCHVGSDRRSSD
MLKNLEHLKQKIDNGADLIITQMCYSAELLVEYLRCVRNAGIVTPIMVGVVVPESLKSYK
TIQAITSIELPAEKRAELRKVESDNAKVREYFVQLALGLIQKVLDAKLDVYGVQFYTMNR
FGGVHEVLNRLQQMGILKETPQEACGDS
>A0A6C5N9Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas macleodii|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLSLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGT
>A0A497RUX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon|TrEMBL
MSKLSENFGKEFIVTGEVAPPRGPDLKEFMHEVEEFKKLMNRLYGVNVVDIPGARLLMSS
LAASILLKQNGIDPIYQLACRDRNQLALEADLIGAAAFGIENVLALTGDHPSCGSSDHPR
AKGVFDLDSATLIKTMKLMNQGKDLVGGDLNKPTNFFIGAALAPGATPIEGEIHKTKRKL
DAGADFFQTQVVFEPSVMRNFLDKYESLMKEDIADKILMGLVPLYSYGMVQFLRTMPGIV
ISEEMGKRIKEADDPVEEGINIASGLIDMAREMNLAGVHIMPAGKIEVLVRLLESI
>A0A4R4KRB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. KC723|TrEMBL
MALGLPSVLPNPRPAIGELIRRGGPTFSFEFFPPKTAKGEQLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGAGVRNVLAVR
GDPPGDPGGEWVRHPEGVLYAEELVRLVRDAGDFSVGVAAFPYKHPRSPDIASDVAHFVR
KCRAGADFAITQMFFDADDYLRLRDRVASTGCDTPILAGVMPVTQMGTIERSVQLSGAPF
PPALAERFARVAHDPEAVRRLGVEQASEMCAKLLDEGVPGIHFITLNRSTATREVWRSLQ
AGARV
>A0A1Q3U9L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. 44-25|TrEMBL
MKITEHIQNANGKTLFSFELIPPLKGHSIQGIYDAIDPLMEFKPPFIDVTSLREDFIYKE
QENGLLQKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLHFLGIEN
VLVLRGDARRGDASFVPTPNGHCYATDLLQQVVNMNNGVYLHEHYDNMMRTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGAKFIVTQMFFDNQRYFDFVNGCRAAGINVPIIPGLK
PITSSKQLISLAKTFHIDIPEDLSDAIHEAKSEKDVKDVGIEWMINQCKELVKFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A3R7RCD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium TMED83|TrEMBL
MTSISFEFFPPKSAEAEEKLWRAIGRLEPLAPEFVSVTYGAGGSTRDRTHACVRRLVDET
RLRPAAHLTCVAAXRAEVNSVVEAYAEAGVRHIVALRGDMPDMGGFAPHDDGYAGSVELV
QAISARGGFDITVSAYPEKHPESRSFADDIDLLKAKVDAGATRAITQFVFDTPAHLRFRD
AVAAAGVSIPIIPGIMPTTNFAGARRMAEACGTSVPDWLSAAYEGLEDDLDTRKHIAASV
ATDQCRMLIDEGFEYLHFYTLNQADLTFAVCRILGLGGGGQESDAI
>A0A3S2V546|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium umbonatum|TrEMBL
MVALSQIHPNWEKAPDGITDGFSLEITAKDVDSLRAAAPNIPPQTPIAVTFLPGEEAPAR
IAAAKAVRDLGFEPMPHFSARRITSEAEFADYLAAVVEGAGVRRCFVIAGDPDRAAGPYE
DSSALIATGLFEKAGIKAIGVGGHPEGHPNMTKEQCWDVLARKCTDITARGMAPLVVTQF
GFDPDAALEWLGELRDRGIAAPVRIGVPGPAGIKTLMRFAARCGVGASASVLAKYGISIT
ALLGSAGPDKLVDALAKGLGEGHGPVRLHFYPFGGLEKTVNWIAQYRASHG
>R6Y6Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. CAG:29|TrEMBL
MNVVDIINKAISERRTRFAFELLPPLKGDGCCGVFGSIDRLIGFDPAYINVTFHREGIKQ
AVRPDGSVEWHVVRRRPGTVGISAAIQKKYGVEVVPHLICGGQSKYDIEDALIDLDFLGL
HNVLALRGDKSQNEKFFMPHPQGHTHAVDLVRQIAAMNRGQFVDGEVEECHHSKFSIGVA
GYPEMHEEAASPEADIACLKAKVDAGAEYVVTQLFYDNARFFDYVRHCREAGIAVPIIPG
IKPLSTVRHLTLLPQTFGCHIPEELGREVLRHADDPKAVREIGTEWAVAQSRELVEAGVP
VLHYYPMGKADNIIKIAKAIF
>A0A3R7PWG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium TMED83|TrEMBL
MTSISFEFFPPKSAEAEEKLWRAIGRLEPLAPEFVSVTYGAGGSTRDRTHACVRRLVDET
RLRPAAHLTCVAASRAEVNSVVEAYAEAGVRHIVALRGDMPDMGGFAPHDDGYAGSVELV
QAISARGGFDITVSAYPEKHPESRSFADDIDLLKAKVDAGATRAITQFVFDTPAHLRFRD
AVAAAGVSIPIIPGIMPTTNFAGARRMAEACGTSVPDWLSAAYEGLEDDLDTRKHIAASV
ATDQCRMLIDEGFEYLHFYTLNQADLTFAVCRILGLGGGGQESDAI
>A0A5E4BVZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmota monax|TrEMBL
MWASEAGSMRWSVPPSISRRRAMETRGLGGPTPPSEGSSSGSESSRDGSRCSTPGLDPER
HERLREKMRRRMESGDKWFSLEFFPPRTAEGAANLIARFDQMAAGGPLFIDVTWHPAGDP
GSDKETSSMMIASTAVNYCGLETILHMTCCRQRREEITGHLHKAKQLGLKNILALRGDPI
GDQWETEEGGFSYAADLVKHIRSEFGDYFDICVAGYPKGHPDAESFEDDLKHLKEKFSAG
ADFIITQLFFEADTFFHFVKACAATGITCPILPGIFPIQGYSSLRQLMKLSKLEVPQEIK
DVIEPIKDNDAAIRNYGIELAVSLCRELLASGLVPGLHFYTLNREVATTEVLKRLGLWTE
DPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELR
DYYLFYLKSKSPREELLKMWGEELCSEESVFEVFAHYLSGEPNRHGHKVTCLPWNDEPLA
AETSLMREELLRVNQRGVLTINSQPNINGRPSSDPVVGWGPSGGYVFQKAYLEFFTSRET
VEALLQVLKKYELRVHYHIVDVKGENVTNAPELRPNAVTWGIFPGREIIQPTVVDPVSFM
FWKDEAFALWIERWGKLYDEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFE
LLNRPAQSERESEAL
>A0A2R7R919|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. HMWF013|TrEMBL
MKDFSLEMTGKDIPALIEARPLIPLGTRINVTFLGNEDLEMRVAAAKAVRELGFVPVPHL
SARRLKSRQQLEEFLGRLQEVDAAGHLFVIGGDPAQPEGPYSDSLAVINSGVLQQFGVRE
VGMSGYPEGHPSIPSETLWRALEEKSAVLQEQGLDTLIVTQFAFDTDPVAGWIDAVRARG
INAPIRVGTPGPAGVKRLLGFARRFGIGANAMIVKKYGFSLTNLMGVAGPDNFVNDLAAV
LAEHSAGGGPGLAGPVGLHFYTFGGLAETATWVRRFNSGQE
>A0A520M886|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thioglobus sp|TrEMBL
MHSATSDPGQPLSILQGHVSPGRLERVLRSGKFAVTAEIAPPDAADVEAVYQRASAFDGC
VDAINATDGSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVTN
ILCLTGDGVQAGDQPDAKPVFDLDCISLLQTVTVMRDQGEFLSGRKLTTPPRVFLGAAAN
PFGPPLDYRPVRLKKKINAGAQFVQTQYCFDLDRLKKYMTQVRDMGLTERCYILVGVGPM
PSARTAAWIRDNVPGVHIPDSVIKRLLSARDPREEGVRICVEMIQAVREIEGVHGVHIMA
YKQEERVREIVGESGVLEGRMPWYPGVDNDQQGQQT
>A0A7X8SVU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. P38BS-XIX|TrEMBL
MRPSPIPAGSFAGSDRKLVDAFSLEITTKDTEALRKAQRALPLGTTVSVTALPGEALDVR
LSAIRATRDLGFEPMPHFAARSVSSREELEHNIRQSRVVGQVDRCFVIAGDNGKPTGPFS
DSLGLIETGVFESNGVRILGIGGHPDGHPHMSEEECWKVLSAKCSAIEGRGMSPLIVTQF
AFDADRVLSWLAALRGRGIGAPVEIGVPGPTSVSTLVRYAARCGVGASASVLAKYGISIG
HLLGSAGPDRFVNKLSVGLVGKHGAVKLHFYPFGGISKTVEWIEGYVNRQ
>A0A0T7FCM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neorhizobium galegae bv. officinalis|TrEMBL
MLSQAGWVFMAMSHARHLRDRSNVLNDFSVEVTTKDTAQLAAMSGAIPKGTIISIPFLST
ESDADRIMAAKMVRQAGYEPLPHIAARRLGSEAMLSAMLSALVNDAQVSRLLLIAGDADP
PKGPFLDTATILRSGLLEQHGIRHVSIAGHPEGHPVQNAAMLRNALMEKRQIMEAAGIEG
SIFTQFAFASEPVLAWIGELRRLGIEIPIHVGIPGPASVRTLLKFAAVCGVSASTAVLKK
YGLSITQLLSSAGPDSLVSEYATALSNADCGDVRLHFYPFGGLRKTVDWLQVCRMQAP
>A0A7Y8JV73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. P7548|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLHNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>M5CUU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia SKK35|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAADKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCDRLVALRGDLPSGMGFPGDMRYAAELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VQRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRRMQAYGDDVDSVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQL
>M2N3N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Baudoinia panamericana (strain UAMH 10762)|TrEMBL
MHITKKLAQAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHSFGPAFIDITWGAGGRMS
HLTCEMVKVAQSAYGLETCMHLTCTDMAQSKIDGALEDAYKAGCTNILALRGDPPREKER
WEKTEGTAFRYARDLVRYIRKKYGGHFDIGVAGYPEGCDDETNADQHIPYLKEKIDAGGT
FIITQMSYDADTFISWCKKVREAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPEWM
EKLDPVKSDDTQVREVGKNLVADLCRKILDSGVTMHLHFYTMNLAASTLMVLEELSMTPS
ADVHHPDLKPLPWRQSLGRNRQDENVRPIFWRNRKQSYVARTQEWDEFPNGRWGDSRSPA
FGGLDAYGIGLKGTNEHNRKLWGEPKSLQDIADLFVSYMSGRVETLPWSEAPISMEADVL
KDDLINLNSRGLLTINSQPAVDGAKSTDPAYGWGPRNGYVYQKAYLEVLVHPAILPTLLE
RMNADQDITYYAVNASGELKTNTSSDGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEF
YHLGQEWSKCYDEESESRRLINEITESWFLVNIVNNDFREKRGIFPLFEGLRVEGVKGEE
RMVNGSAQVNGLKHEGTDVPAVPGTGTGAATAGLPAADGHSKS
>A0A2D6XXX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aestuariibacter sp|TrEMBL
MVSYAQGVDALNQSLSELRDIDVSFEFFPPKTESMEKTLWKSVERLAPLNPSYMSVTYGA
NSGERDRTHDIVKRIQQQTGVTAAPHLTCVDATKDELKQIAKDYWDSGIRRIVALRGDLP
QGVEKTDMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDASVYLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGYLHKMFEGL
DDDDQTTRNLLGANIAMDMVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRANGN
>A0A1Q4GRM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus sp. 65-29|TrEMBL
MTQRTFSFEFFPPKTPEGVEKLRATHRQLAQLKPKFFSVTFGAGGSTRDRTLETVREIQA
SGSEAAPHLSCIGSTEASIRDILDEYRRQGIRHLVALRGDLPSGSMDVGEFQYANELVAF
IRKETGDWFNIEVAAYPEIHPQARSYAEDLQNFKRKVDAGANAAITQYFFNADAYFRFVD
EASALGVSIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLESYGEDLASIRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPSSTIWQRLGL
>A0A3N7CS73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herminiimonas sp. KBW02|TrEMBL
MKEQNFSIEFFPPKTPVGVEKLRVTCAKLSELNPKYFSVTFGAGGSTQQGTLETVLEIRA
AGQDAAPHLSCLGSSRESLRAILAEYKSHGIKRIVALRGDLPSGYGSMDMSSSEFHYANE
LVEFIRTETGDWFHIEVGAYPEMHPQAKSPQDDIANFVRKANAGADSAITQYFYNADAYF
RFVEDARKAGANIPVIAGIMPITNNSQLMRFSDACGAEIPRWIRLKLASYGDDAESIRAF
GLDVVTDLCERLLAGGAPGLHFYSLNQAVATQTIWTRLNLSQK
>A0A2T3HP77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter yulinensis|TrEMBL
MKITEHISNAKGKTLFSFELLPPIKGQSIQWVYDAIDPLLEFNPPFIDVTSLREDYIYKE
QDNGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARQADPSFIPTPGGHCYATDLIQHIKNHNEGKFLHEDVESFKSDFCIGVAGYP
EKHFEAPNLGTDFKYLKKKVDMGAEFIVTQMFFDNRKYFDFVKKCRENDINVPIIPGLKP
ISNAKQLISLPKIFHIDLPEDLCDAVQHCKSVKEVKEVGTHFMIKQCKELIEFGAPVLHF
YTMGRPEQTKEIARAIF
>A0A2T6NFN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium symbiont of Ctena orbiculata|TrEMBL
MHTEHQQRNFSFELFPPKTEKGLENLKLNVAELNTKQPAYFSVTYGAGGSTRQRTFDTVE
WLMDEQITTAPHLSCIGANRDEILQILEHYKSIGIRHLVALRGDLPSGTGLGELGDLNHA
NQLVELIQETYPRFFHIEVAAYPEFHPQANSPEQDLTYFKRKVEAGADSAITQYFYNADA
YFRFLDNCQQLQIDIPIVPGIMPITNFTQLARFSDACGTEIPRWLRKRLEGFGDDLEAIR
SYGTETVIRLCERLLEGGAPGLHFYTMNHAKPTLAIWQALSL
>A0A1Z5H670|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bathymodiolus platifrons methanotrophic gill symbiont|TrEMBL
MTIKNKADLFSFEFYPPKTEQGDLNLEQVHRDLAKLNPDFFSVTFGAGGSTRDKTYDTVV
KIQKNGVSAAPHLSCVASTKENIREILANYREHGVSKIVALRGDLPSGMMSAGEFRFANE
LVDFIRAETGDHFQIHVAGYPEVHPQAGNATEDFNNFKRKVDAGADAVITQYFYNAEAYF
YFLDKCEKSGINIPIVPGIMPITNYAQLFRFSDMCGADIPRWMRKTLECFGDDKASIMAF
GEDVVSKLCQELLDNGAPGLHFYTMNQSKPTLAVWDNLSFA
>A0A1Z8SJR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetia bacterium TMED53|TrEMBL
MTWELQGATILEVVPPTLESGDEGVSKRLRRVEKLLSEGSFDAVNLPEIHDEESRDTRGV
RKLDFSNRLDGRIFGQMIREQFDVPVIVNHVVAHAPLDHQILWLHETVREYGITDMILVG
APHDRQIWPGPSVAEANNAFKSEFADSDLRVGNICIPERPGSPIPESERMAEKVGAGADF
FTTQILFCAAEISQLWQQFSKNHSELLQIPVLISLCPVKKSENLAFLRYLGVQVPNQVEE
TLGQIAADECLDASLEILCELQKQILESSNKIKDLASPGWNIAPVGSIPASAVLDLMQRL
PSAIPS
>A0A0P9S0S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. hibisci|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A286YFD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Homo sapiens|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKAHPECERNGGSMTLRP
DALRWSHSCPAFLLHSAASLGNSTLLRVSPTPASTPPPDNGS
>A0A6A7KAD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalibaculum sporogenes|TrEMBL
MKVTEIMKQKLCFSFEVFPPKSENPIEPLLNTLDHLYKFDPDFISCTYGAGGTNAGRNVE
ICKAIQDSGKSTAVTHFTCIGNSKEKIAQELQAYLDRGIDHILALRGDFPKGWKETRGDF
NYANELTEFIKENFPKFCIAVAGNPEKHFQADSFDTDTTHLRIKQDSGADFIMTQLCHDV
NQYQWWVEKIRKAGVSIPIDVGVMPVLVKDPTIRMAVSNGSAIPRDLAEIIGRYGDNPED
FKKAGMEYTIKQIHKFINAGIDGLHIYSLNKWKDISDIVNEIGIRKIQE
>A0A8F8P7H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. B21/90|TrEMBL
MTSTPDTGRSDVSISFEFFPPKTPDMEGQLWAAITELTEWQPEFVSVTYGAGGSTKAPTL
NTVRRMIAETPLPTASHLTCVSATREDTHRVVDELRAAGVRHFVALRGDPPGGIGTAYQP
HPGGYENAAALVAGLRDIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDVFETYMERVRAAGIAIPVLPGIMPIQNLTQLKRFAGMCGTSIPSYLDERFAGLDD
KPEERAKVAADVAAEQIEDLVRRGHREFHLYTMNRAPLVGAVLERLGFKRTKIAAAAGAA
A
>A0A163MKV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Absidia glauca|TrEMBL
MQTRQISSGSPTMKVIDKIKKAEEEGRIYWSFEYFPPKTAQGTQNLYDRIDRMKQYGPEF
IDLTWGAGGSSAKQTIEIVKTAQSVSKVETMMHLTCTNMPVEMVDEALKAAKDCGCQNIL
ALRGDPPHGQDKWESCEGGFNNAIDLVKYIRLKYGDYFGIAVAGHPEGHIDNPSKEDDLK
HLKDKVDAGADLIVTQLFYDVDMFLDFVTKCRAIGITCPIVPGVFPIQNYQGLKRVISFN
DNYVPESIWNDLEPIKDDDAAVKEYGIQLTIQFIEKMLAAGIKGVHFYTFNLERSTRLIL
ERLNLIPAKEEAALTQNTAQSSVA
>A0A031J765|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. RIT357|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKQAGIQRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A167JA13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC 33097 / NRRL 1555)|TrEMBL
MKITDKLRKAEGTGKISYSLEYFPPKTEQGLVNLFDRLDRMAKLNPAFVSCTWGAGGSTQ
DRSIELCSTVQSIHGLDTLMHLTCTNMEKEKIDKALEAAKAAGIQNILALRGDPPRGHEY
WTPCENGFSHAIDLVKYIRERYGDYFCIGVAGYPEGHVDAVSKSQDLQYLKEKVDAGADF
VLTQLFYDVDGFAQWIKECRRLGIQVPIIPGIMPIPTYQTFRRMINLCKLHVPPSMLAEL
ESIKSDDEKVKEFGVRLAVSMISELHTKHKISTFHISTLNLERSTRLILQQLNLVPKEKA
LSGENLLGLPDIKATSWGSKLVEVNLAESWDEFPNGRYGDSRSPAFGENTFGQGHVQQTS
EATRKWGYPKTEEDVTNLFTKYILGKLSSLPWCEDALQTESDVISQRLVDINKRGYWTVS
SQPAVNGVSSQDPVHGWGPKGGYVYQKAFIEFFVSDKQVKDLLKCLGENDEITYYAINRA
GELLSNVADPDAQNAVTWGVFPGKEIVQPTLIERANFEAWKEEAYLLWTEWEQQYPRESD
TAKLLQYIGDHYWLVNVVHNDFQQPDSLFDVMISC
>A0A3G7A9N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CMR5c|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASCNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKVPSAPHLSCVGDSKDDLRGLLQQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VNFIREETGSHFHIEVAAYPEMHPQAHNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVQKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
TQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>N1LZF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus aetherivorans|TrEMBL
MTFDSDSGPDGGGESRTPSVVDRFRAPRGARIPFSVEFSPPRDADAEARLWRAVREFERL
GPAFVSMTYGAGGSTRDRTVRVTGQLAQETTLLPVAHLTAVGHSIDELRAMVGAYADRGI
TNILALRGDPPGNPLGEWTRHPEGLEYAEELVRLVRDLGDFHVGVASFPEGHHRSPDLEH
DTRYLVHKLRAGAEYSITQMFFDVEDYLRLRDRVVAYDPEQGAKPIIPEIMPITSLRTAR
RSLELSGSRLPAALEERLVRAAGNGPEEDRAAVREVGIDVATEMAERLIAEGAPCLHFIT
LNFARATREVLARLGIAVPTAV
>A0A2R4M3K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Celeribacter baekdonensis|TrEMBL
MTQAPNISFEFFPPKNIEACFSLFETVQALEHMQPGFVSVTYGAGGTTRELTHDAVALLN
RKYGWNVAAHLTCVNATREETLEIANSYKSVGVNEIVALRGDPPKGAGQFTPAPGGFANS
VELIEALAATGNFKIRVGAYPDPHPDATDDSADIVWLKEKFKAGADSAITQFFFDADTFF
RFRDRCAKEGITGKIIPGILPITSWTGVQKFAAACGTPLPAHYAKAFETAEDQQAASVDL
CTKLCETLIQDGVEDLHFYTLNRPTLTKAVCANLGVTG
>A0A1M6HJK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenibacter nanhaiticus|TrEMBL
MKITDHIKNAQGKTLFSFEIVPPVKGKGIQELYNNIDPLMEFKPPFIDVTTSREEYIYIE
RDGLLDKKLTRMRPGTVGICASIQHKYKVDTVPHLLCGGFTKEETEYVLVDCHYLGIDNI
MALRGDARKEEKYFNPTQGGHSYAKDLVKQIKNLNDGNYLHDTVDAAYSVDFCIGVAGYP
EKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNQRFFEFVAAARDMGIDIPIIPGIKP
IAVQRHMQLLPQVFRIDLPEDLIQAVDACKNNAAVRQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIQAIAKALF
>A0A2T1DH42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phormidesmis priestleyi ULC007|TrEMBL
MSHPSHPLPSFRSAAQSGEFLITAEVAPPKGGNPAHMLEMAQLLKGRVHAVNITDGSRAV
MRMCSLVSSALLLQQGIEPICQVACRDRNSISLQADLLGAHALGIYNILALTGDPVKAGD
HVDAKAVFELESVRLLQLIAKLNLGADWKDQPLTDGETSLFVGAAVDPQCGSWSGLQRRF
ERKVEAGAQFFQSQLISDFDRLEKFMDHLGSPAGKPILAGIFLLKSAKNARFINRCVPGV
QIPEHIIDRLERASDPLQEGVMIAAEQVQTARQLCQGVHMMAVKREDLIPQILDLAGVAP
LSKATPVTA
>A0A209C5B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CS113|TrEMBL
MTTLRDLLAAGRPSFSFEFFPPKTEAGVRTLWASIRRIEALAPAFVSVTYGAGGSSRDRT
VEVTKRIAAETTLRPVAHLTAVGHSVAELRHIVGQYADAGVRDVLALRGDPPGDPNGPWT
AHPQGFTHAHELVSLVRELGDFSVGVAAFPERHPRSPDWESDIRHFVAKCRAGADYAITQ
MFFRAEDYLRLRDRLVAAGCDTPVIPEIMPATDVRQIRRFAELSGAAFPEDLAHRLEAAR
DDPATGHRIGVDHATAMADRLLAEGAPGLHYITLNRSTATLEIHADIHASRSSRALASHH
>A0A5P9WS52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SYP-A7193|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSAAWDTDVAHFVD
KCRAGADYAVTQMFFQPDSYFRLRDRVAAAGCDTPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A2H6LLQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc cycadae WK-1|TrEMBL
MYHTHSPTVSLFQKAAQAGEFLVTAEVAPPKGGNPAHTIEMAATLKGRVHAVNITDGSRA
VLRMSSLVASAILLQNGIEPVCQMACRDRNRIALQADLMGAHALGIRNILALTGDPVKAG
DHPDAKSVFDLESVRLLQLIQKMNQGVDCNDKPLTDGATDLFVGAAVDPQCGSWSGLQSR
FERKIAAGAQFFQSQLITDFERLEKFMDKIASVHNKPILAGIFLLKSAKNAQFINRCVPG
VNIPEHIIDRLAKAKDPLEEGVKIAAEQVQIARQLCHGVHIMAVKREDLIPKILDLAGVE
SVELVVAK
>A0A356UC76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas sp|TrEMBL
NLDKDEVLNMLEGFKQEGVENILALRGDVNPSLIPKQDFRYASDLISFIKENGDFNIIGA
CYPEGHNECPSLVEDIRNLKI
>A0A8D0WER7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKH
IRSEFGDYFDVSVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLK
ACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GQELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIV
DGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEES
PSRMLIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>A0A2V7R669|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTITLRDLLNDGKVHVLDGAMGTMLYSKGFFLNVCYDELNVKQPKLVQEVHEAYVRAGAE
LLETNTFGANPVKLRTFGLADDTEQINRTAAELARKASAGRASVVGAIGPLGVRLEPFGA
LSREEAFAHFQRQVQGLVAGGVDGFILETFSDVDEIHQALRAVQSVSDLPVIAQMTIGDD
GLTHYGTAPETFAKQLAEWGAAVIGVNCSVGPAGVLEAVEKLVKATDRPISAVPNAGLPK
DVGDRKIYLASPEYMASYARRMIEAGARIVGGCCGTTPEHIKKIRDYVASVVPRHQPVVQ
TRETIAPPAGVKEVPLATRSHWGAKLAAGKLVTSVEIVPPKGVDPTPMLEQCRALKAAGV
DAVNVPDGPRAQSRMGVLPSAILIQKEVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRN
ILIITGDPPKMGPYPEATAVFDIDSIGLTNLVYRLNHGLDPGNNPIGAPTRWAIGVGVNP
GAVELDRELSRFHWKVDAGAEFAVTQPVFDVRQLESFLKRVETYRIPIVAGIWPLVSLRN
AEFLANEVPGVVVPPEVLERMRRAQDKGKEAALAEGVKIAREMFQQVKGSVQGVQVSAPF
GRVEVALEVFG
>A0A6B1I3S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MSLTALHPPARYSGAWQKKPLRHLLETTDTFVHIVELVTSRGLITERDGRKVLALARRLA
EHPQFHALSITDNPGGNAMINPDTLGTDLISRGQDVIIHLSCKDWNRNALQGRAWQLASE
GFNNILALSGDYPISGYQGTAGGVFDLDSVGLLEMFAAMNAGLKMKKGKRTQRMEATDFY
LGAVVNNHKRYEREVMPQYFKLAKKIHVGAAFVISQIGYDARKQDELLKYMALCGLDVPV
IANVYVLSRPAARFFHKGHIPGVEVTDELMAVVEKQAQANDKGRAFFLELAAKQCAIAKG
LGYRGAYLGGHLQYGDYEKILALAATYSEDDWRDFAVELCFSFADEFYFFEPQGDTGLSS
TTINRAYLASKEQAALRQARGRLPLSYKLNRRIHDQVFAPESAGFRTGAHLARALTEHPK
AAKLFHAAEHALKIAAFDCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTRQGKCEVGD
KDCIWARAYDRLKAYGEEEQMLGDAAVIKDAALQGTSAWTNAFLQKDHHGKKKDSQ
>A0A2V7MEP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYGKGFFLNVCYDELNLKQPRLVQEVHAEYVRAGAEILETNTFGANPLKLNSYGLA
DETEKINRTAAELARGAAGGKASVVGAIGPLGIRIEPFGPTSQLEAEALFARQVQGLLAG
GVDGFILETFSDMDEMHAGLRAVRAASDLPVVCQMTIGTDGLTYYGTDPDTFTKQLAAWG
ADVIGVNCSVGPAGVLDAVEKMVKAADKPISGQPNAGLPKDVGDRKIYLASPEYMASYAR
RMIEAGARFVGGCCGSTPEHIKKIRDYVASVVPCQPSVVVSRAQVQAPPDVTPVPLAEKS
RWGAKLARGEIVTSVEIVPPKGIDPKPMLEQCRALKAAGVDAVNVPDGPRAQSRMGVLPS
ALLIEREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLTNLVYRLNQGLDPGNNPLGGATRWAIGVGVNPGAGDLDRELSRFAWKVDAGA
EFAVTQPVFDVRQLEAFLKRVEQFKTPIVAGVWP
>A0A7C2LSJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTLLYARGVPLHRCYDELSLTDPELVRRVHEDYARAGADILETNTYGANPVKLARYGLE
AHVHAINARAAELARRAAGDRACVAGAIGPLGVRIEPYGPTSVEEAQAFFRSQVEGLLDG
GVDLFVLETFSDLLELQQALQAVRAVCDLPVVAQVTVREDGRTTLGTDAATCLARLTEWG
ADVVGFNCSIGPSLMLDVIERARSATDRPLSAQPNAGLPKEIEGRTMYLGSPEHFAQVAL
RLVRHGVRFVGGCCGTTPEHIARMANALRIVRPTSSTTVAVRSPQAEEEAGTAAVPLAQR
SRWGAKLAQGAFLTTVEVLPPRGADPTPLLEAARQLHNAGVDAVNLPDGPRAQSRMSALL
GAVLVHQQVGLEPIVHYCCRDRNLLGMLSDLLGAHALGVRNLLLITGDPPKMGPYPDATG
VFDIDSIGLTNLVARLNRGLDPGGNPLGQPTSFVIGVGVNPTAEPLDTELRRFFWKIDAG
AEFAITQPVFDVDQFFAFLEELDRRNLRLPLVAGIWPLASVRNAEFLANEVPGVRIPEAV
LTRMRRAGEQGGEAATAEGVAIAQEMLERLRPYIQGVQISAPFGRVGLALRVLEALPATD
RPPPAPTPAATR
>A0A7H0HDY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax monticola|TrEMBL
MSPSTAFPVSFEFFPPKTPEGADKLRGVRQQLYARRPEFCSVTYGAGGSTQAGTFAAVQE
ILAEGVSAASHFSCIGATRASVREQLAQLKAMGVKRLVALRGDLPSGYGIGGEFHYASDL
VAFIRAETGDDFHIEVAAYPEVHPQARSAEADLQAFATKVRAGADSAITQYFFNADAYFR
FVHEVRRLGLDVPVVPGIMPITGASQLMRFSDACGAEIPRWIRLRLQGFGDDTASIRAFG
LDVVTELCEQLRRGGVPGLHFYTMNQSAATLAICERLGI
>A0A2V7ES90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTTTLRDLLNDGKVHVLDGAMGTMLYSKGFFLNVCYDELNLKQPKLVREVHEAYVRAGAE
IIETNTFGANPVKLRSYGLADDTEKINQAAAELAHQAAAGQASVVGAIGPLGVRIEPFGA
LAREEAFAHFGRQVKGLLAGGVDGFILETFSDLDEIHEALRAVRSLSDLPVIAQMTIGED
GLTYYGTSPETFAQQLTAWGADVIGVNCSVGPAGVLEAVEKMVKVTDRPISGVPNAGLPR
DVGDRKIYLASPEYMASYARRMIEAGARFVGGCCGTTPEHIKKIRDYVASVVPRHQPVVV
SRETIAAPAGVEEVPLSARSCWGAKLARGELVTSVEIVPPKGVDATPMLEQCRALKAAGV
DAVNVPDGPRAQSRMGVLPSAILIQREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRN
ILIITGDPPKMGPYPEATAVFDIDSIGLTNLVFRLNHGLDPGNNPIGAPTQWTIGVGVNP
GAVDLDRELSRFAWKVDAGAEFAVTQPVFDPAQLDTFLKRAEQFKIPIVAGIWPLISLRN
AEFLANEVPGVSVPESVLARMRQAQEKGKDAALAEGVKIAREMFQQVKRAVQGVQVSAPF
GRVEVALEVFR
>A0A8D1M0G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MDRPKAKCLPAGQCCPSLGVRALEAGISRSSVPPAISRSSAMVNEPRGNGGPGPRCEGSS
SGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEVTG
YLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACSEMGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKVGASLGHRVRGRHIYA
TIRQSRSAPPIQALCQTDTQTEPGPCPLRAPSLAREAIRG
>A0A7L8RTN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter sp. SR38|TrEMBL
MNQFPLSRRSDIGNKIRVSFEFFPPKNDDMEARLWETVTRLEPLRPQFVSVTYGAGGSTR
ERTARTVKRILEESTLTPAAHMTCVDATREEVDQVIAEFAAMGVKRFVALRGDPKEGVGA
AYQPHPGGYANGAELVGALKAQGDFDISVSAYPEKHPESPDFVTDFDMLKRKVDNGATRA
VTQFFFDNDLYERYVERARKAGIYIPIVPGVLPIHSFTQVANFASRCGAHVPGWLAERFE
GLDKDPQTHALVASAVAVEQVLDLVERGVNDFHFYTMNRADLVVAVCHMIGIRPQPVVQG
SAAA
>A0A7K6M3L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panurus biarmicus|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRYLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDELEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A2V7K6H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYAKGFFLNVCYDELSVKQPRLVREVHEEYVRAGAEILETNTFGANPLKLASFGLA
DDTEKINRAGAELARGAAGARASVVGAIGPLGIRIEPFGPTSQGEAEALFARQARGLLAG
GVDGFILETFSDLSEIHAALRAVRSAGDLPVVCQMTIGTDGLTYYGTDPETFTKELTAWG
ADVIGVNCSVGPAGVLEAVERMVKVTDRPISGQPNAGLPRDVGDRKIYLASPEYMASYAR
RMIEAGARFVGGCCGSTPEHIKKIRDYVASVVPRQASVVVPRAQIQAPAGVTPAPLVAKS
RWGAKLARGELVTSVEIVPPKGVDPAPMLAQSRALKAAGVDAVNVPDGPRAQSRMGVLPS
AIMIEREVEIETVIHYCCRDRNLLGMLSDIIGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLTNLVYRLNQGLDPGNNPIGGATKWVIGVGVNPGAIDLDRELSRFAWKVDAGA
EFAVTQPVFDQRQLEAFLKRVEQFRIPIVAGIWPLVSLRNAEFLANEVPGVNVPDEVLQR
MRKATDRGKEAALAEGVAIAREMFARVKTTVQGVQVSAPFGKVDVALEVFRT
>A0A2V7KQT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYGKGFFLNVCYDELNLKQPRLVQEVHTEYVRAGAEILETNTFGANPLKLGSYGLA
DETEKINRAAAELAHAAADNRASVVGGVGPLGIRIEPFGPTSRAEAEALFARQVQGLLSG
GVDGFILETFSDLEEIHAGLKAIRAASDLPVICQMTVGTDGLTYYGTDPETFTKQLAEWG
ADVIGVNCSVGPAGVLEAVEKMVKATDKPISAQPNAGLPKDVGDRKIYLASPEYMASYAR
RMIEAGARFVGGCCGSTPEHIKKIRDYVASVVPRHPSVVVARGQVRAAPDVQPVPLVDKS
RWGAKIARGELVTSVEIVPPKGIDPKPMLDQCRALKAAGVDAVNVPDGPRAQSRMGVLPS
AILIEREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLANLVYRLNQGLDPGNNPLGGATKWAIGVGVNPGAVDQDRELSRFAWKVEAGA
EFAVTQPVFDVRQLEAFLAKVEQFKTPIVAGVWPLISLRNAEFLANEVPGVSVPDEVLQR
MRTAQEKGKEAALAEGVAIARDMFSKVKQLVQGVQVSAPFGRVEVALQVFQ
>A0A435H2S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.001.04.2.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A1M7H5Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium xanthum|TrEMBL
MKVTQHIEAAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKLGGNDFAVDLVKQINQLNCGKYLHEVMDVDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVEAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A4R9IZT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira yanagawae|TrEMBL
MHISQVLQKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEQTGLTIVSHLTCVGSTKEEIREILKRYEKSGIHNIMALRGDPPKGQTEFQKT
ENGFGFAGELVGFIKKEFPNMGIGVAGFPEGHPSTPNRLKEIEFLKWKVDQGADYICTQM
FFDNNSFYDYVERCEIAGIKVPIIAGIMPITSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDSFAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRKIYESLGIRNFDTIV
>A0A4V1CWX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides daphniae|TrEMBL
MTPPRQGTPSEDVRQVAERTVQRLEPLDVDALVLYDIDDESDRNPAERPFPYSATLDPAD
FADQLDGWKKPVVIYRCVGKYTPDHLGEWLGAQDPDRVMTVFVGASSRDKEVAVSLPQAQ
ELRREVQPDLLLGGVAIPERHQSRGDEQARLLAKQSAGVSFFVSQVVYDVNAAKDLLSDY
HYACREAGVEPVPLVFTLSVCGSLKTLEFLEWLGVNVPRWVQNDLRHSSDTLQQSYDQCV
ATADELIAFADRLGLPIGFNVESVAIRKAEIEASVELAGHIRKRLEEYRDF
>A0A4Y8TQ59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp. A23|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPEFCSVTYGAGGSTQAGTFTMVRDIQNE
GVGAASHFSCIGATHEKVRAELNELKAMGVKRIVALRGDLPSGYGLGGEFQYASDLVAFV
RQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VRALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A435U3F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.14.1.1|TrEMBL
MNDMRQELIQTRGSATFAFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLATAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLEICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWLRVNER
>A0A4Q5EW28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. aa_0143|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPGTIEHLMKYRPEYISCTYGAGGGNVGANRE
VCQMIRNAGTVPVTHFTVIKNTKEGIRQQLEQYLADGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A7C4BHQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MTFAEKVGAGKFVITSEVGPPKGIEVDEMLREAETLRGKVDAFNVTDLQSSVMRLGALAV
CRLLQERGLEPVFQITCRDRNRLALQSDLLSAAVFGLKNVLCLTGDHPVLGDHPGAKPVF
DLDSVSLLHAATTLMSGKDMAGNDLAGKPDFFLGAVVNPGADPLEPQLFKMERKIAAGAR
FFQTQAVYDIDAFAKFMKRVEQFRVPVLGGIVLLKSAGMARYMNEKVAGVHVPDRYISMM
AKAAKDARAQVSVAIAAELINGMKDLCQGIHIMPLGWEKHVPAVLSACGFSS
>A0A158SRJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. KN65.2|TrEMBL
MTAAIRPADAPLFGVQPGDISVSFEFFPPKTEKMETQLWEAITQLAPLSPSFVSVTYGAG
GSTRERTHATVSRIIRETDLVPAAHLTCVAASKAQIDEIVDRYWEAGVRHIVALRGDPPP
ADGGRFVPHPEGYASAADLVAGIKARHGFDISVAAYPEIHPDATSAEADLDNLKRKLDAG
ASRAITQFFFSTDAYFRFLDKALAAGITAPILPGIMPVTSFSAIRRMSGNTEIPAWLEAM
FEGLDDRPGPRALVAAVAAADLCKRLYDGGVRDFHFYTLNRAEQAYAICQLLGLRPKEIG
>A0A7X8GR86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MDRVIFEIITPPETWAPQKVDEWAQRICDILKRHSLRYLNIPEVVNETRDGDRRVRYIPK
MDNVSFAKVLARTCPGAVPVLNKISVRIPRPEFEAWVQKVYEQGVRHFVIVGGELPDYPY
PGYTVSEAASLIKRSFKDAKVGGITIFTRPHEAERIAAKIEAGMDFFVSQIIFETANLKH
VLIELDKILPQSSLDAQARFPDIYVSLAPAARIRDIEFMMWLGVEIPSAILAYLAKDDEE
VEERTFEINMRVQEEIFEFISKKGYRLGFNVEHVIYTNLGLSERLVDEITERMGR
>A0A7W0NC96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexia bacterium|TrEMBL
MAHPLLEQLSDGPLLVDGAMGTMLYETGVSLDESFDALNLSRGGEVAAVHRAYLAAGADI
IETNTFGANRLRLETFGLGDRVREINMRGVKLAREEREISGQPVLVAGSVGPIARTLEPF
GTTPVREAQNAFREQIEALLEGGIDLFIIETIGSLVEATEAVRAARSVSDLPIIALMTFA
EDGQTLAGHRPEEVVDRFAELGVTAIGANCSVGPQRILPVVLAMRQRLNRLGSGSPYLAC
MPNAGWPARVGTRVIYQSSPEYFAQFTHAALNSGVSLIGGCCGTTPEHTRAMRGVLETWK
KEDQQPKDPEERGPKTHLSVSPRLTTKPDRDILASNDPTEFARKLGRQFLVCVEIDPPKG
LNPAKALEGAKLLKAAGVDAINVADSPMARVRMSAQTLCYLIQHQVDIETILHFTTRDRS
LMGLQSELLGAHAVGVRNILALTGDPPSLGDYPDSTAVYDVDSIGLIRVLARLNEGTDLA
GASVGHKASFTIACALDPTRSDLQEEARRLRTKLAAGAQFVMTQPIYDVAVWRQFLQVFG
ESEVGVPVMVGILPLQSAKHAEFLHNEVPGITLTEGALVRMRRAGADGRREGCGWRKNFS
RNYA
>A0A7C3U5K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Korarchaeota archaeon|TrEMBL
MISLELNPPSRPSLDEIYEKIRKYNSFDAFIITELAMRREEDRWMDTMYTAIKLKEATGK
RIIPVMTSRESTKRGILSRILMAIHGGIDELVIVRGDQSPYGGAFGMTTVEIIRTIRSLC
ERFSKRVTVYVAANPTRDLEGEIVRAAEKLSSGADAMITQPTLDTNLLRKFIAGLRERGF
DNPVIGSIMILNSRNSAEIMERRCGIRFPEWFKEELERGNWRDSLLTSIREIADICDGVH
ISPIAEQDFSVLLAEEARKTLRDRDEQLPIFLP
>A0A7X7LCH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MNDWFEKGKYLVEILTPKQATEDIEGDLQKFADKYAAALALDFVVCITDNPMGMLSFTAV
ETIEATGVPVNPERLLVHLNTFHRKQDLDAMLRTMADRGVKYLLAVSGDGTERLHRLEPD
ELGYEANNITSVELIRYIRREFPGVFTFGVAFNHYEPQESEREKMRRKLDAGAAFVITQP
VIKRHDNVDWLRSLGVPLIAEAWMSKRIDLVAECVGYKLSEEELRYDPIDNLRLLKANYP
DFGFYLALLGMKKQVLEVKALDS
>A0A7C1DNE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MTSFRDTIKDQLILIDGAMGTYIYQKGVFIDKCYDALNLSNPDLIESIHREYVEAGACVI
ETNTYGANRFKLARHSLSDRLAEINMQGVRIARKAAENAVYVAGSIGPLGVEIAPFGGIS
RKEARDAFAEQSKPLLEEGVDLLILETFRNLDEIEQAVLAIRSLAALPILAHMAVLEDGT
TEYGSTVEETIRRLSGLEVDAVGLNCAVGPKSMLDFLERTVCLTGKPISIMPNAGRPHSH
DGRTFYMSTPEYFGVYTKRLIEAGARILGGCCGTTPVHIRKMADALAQKETRTRIRPESS
ITLHEEKAALPEPVPFPEKSRLADKLFRKEFVTLVEMVPPRSRELEKHLSGARLLQENRI
DAINIPDGPRASARLNGLALAVRLQTEIGIETVLHYTCRDRNLLGMQSDLLGASALGINN
VLAITGDPPMMGDYPAATAVFDIDSIGLTQLLSRLNRGLDIGRRPVGAPTGFLIGVGVDP
NSVNVEREVARFRQKVEAGAEFAITQPVFDFAVLEGFLEKILDFAPPVLAGVWPLVSLRN
AEFMKNEVPGVVVPDSLLKRIGRFDTREDQLKAGVEIAREMAAHVRKRTQGIQVSAPFGR
YGTALDVMQGH
>A0A2A4CD54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. IDO3|TrEMBL
MSSLKQALNEGRFVCVFEVVPQQSPARLAALEQIVQRGHLAGWPLLPAFADRVGLHSDLS
PLEGAEALGNPAASLLHFSGKDRERADLLQQMNLMKARGLEQLLLLSGDRLPGHRPGEAP
VRYLESVAALQIAREHCPDWLLGAALNPFKYREEEGGAQYLKAQKKLLAGADFLTLQLGF
DAAKHIEAQTWMRAQARMKPMLGCVMKLTDTRAAVLQAVPGVIVTESMRALLGREQQVSR
AYAGARSLERLALQIVGLQLMGYAGAHVSGVHTLDELLSLEQAIAEQRDGMTSLTDWGER
WRASWQMPGAPLVSFTPESGAWALGRSDVTATRRERLRHTLLSSVHDQFFSRTGWLGRAF
GWSVTRPIWKVGVAANALHAVERAVKRPLIGCDTCGSCRLQDTLYVCPETCPKGLANGPC
GGTWLNRCEFGDRECVHSVKYRIAKSADQLPVLAQTLIPCIEAENRHRSSWPEWFEPEDT
TQGAEASRRE
>A0A0A1SY93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Torrubiella hemipterigena|TrEMBL
MHLNQMLDESKRTGEPSFSFEYFPPKTAQGVQNLYERMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQTVYGLETCMHLTCTDMGLEKVNDALHRAYKAGCTNILALRGDPPRNQET
WTATEDGFQYASDLVKHIRKTYGDHFSIGVAGYPEGCDDNKDEESLLEHLKIKVDAGASF
IVTQMFYDADNFIRWVGRVRDLGITIPILPGIMPIATYASFLRRANHMQCKIPQEWLDTL
EPVKNDDVAVRELGTNLVADMCRKLVANGIHHLHFYTMNLANATRMVLEELNWTPSAERP
LQQALPWKPSKGLGRREEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRNKWGEPVSVKDIANLFVRYLNNEVDTLPWSEAPLTSESNSIKDKLVE
LNQKGFLTINSQPGVDGVKSSHPVHGWGPSNGYVYQKGYLELLVAPEVMPEVISRIEKDA
NLTYYAVTKDGELQTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCFEANTPSRVLLEKVMDQWYLVNIVNNDFHDNETLFDLFKGLQVADMASSPVIG
>A0A1E7HV98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium S5133MH16|TrEMBL
MNAQSRLQEILSKGEFAVTAECGPPRGATPEVVRKKGELLKGYVDAVNVTDNQTAIVRMS
SIAACSHLLQMGLEPVMQMVTRDRNRIALQSDIMGAYSLGISNILCLSGDHQSFGSQPDA
LNVFDIDSMNLIRTVQTMREQGKDMSGFELNGPPRMFIGAAANPFADPFEYRVIRLAKKI
DAGADFIQTQCIYNMDRFKEWMKMARDEGLTEKVHILGGVTPLKSAGMAKFMNNKVAGMD
VPEPLIKRMAGVPKEKAVEEGIKICLETIAELRDIEGVHGVHIMAIEWEEIVGEIVESAG
LVPRP
>A0A1F9NH98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium GWB2_56_26|TrEMBL
MDFTGKSGKKLIITTELGPVKGVLTAESLTKAKGYLPLDGINVHDCPMGNLRINAIAMAA
LIQQELKMEAIPHFTCRDRSLLGTQADLLGAHALGIRNLLVTTGDPPKHGPYPSKPVYDY
NTVELIGLIKKMNAGLDYNDKEFGGHTDFKVSCTALPTAKDRDREIERMARKMKAGADFF
QTQVVYDAEKTISFMEKAKSLGKPILIGLMPLKSVKMARFVNDNVQGIDVPEEIINRMEK
DGVTGIEIICEFIARVHPVIDGIHIMAMGDVQGTNRIIEFVRSLGK
>A0A520W669|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MRAISDIYAECSALKRTVISVEFFPPKTPKGEESLFDRVLPRLAEAKPDFCSVTYGAGGS
TRDKTLNVVDRIQRDFGFVGMAHLTCLATSATDILNYVNEANAKGIRNLLALRGDPPSDN
PAELVPEAGFDYAYQLIDFIKQHASSNTSIGCAGFPEGHIACTEGRETDWQRLRNKVDHG
AQFILTQLFFDNDDYFRMVDYLTNILGVNVPITPGILPILSSAQIKRFSALCGASLPAPL
LAKLDRLGDDDEAVTAFGIEYASKQCEALLAGGAPGLHLYSLNRSKAVLGIVRNLGLVDR
>A0A2V4NW66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium esteraromaticum|TrEMBL
MHTTPFSFELYPPRTAESTRALHDTIDRLAEVHPDFISVTYGAGGSTGGRSLEVLRYIRA
HTDTEPLAHLTCVGNTYAGAARLIREFLDAGVLSFLALRGDPPAGQNEDDVFLGDLESSA
QLVQLIDRVQAERAPYEESPVRGNPGAVRVAPRRRVNIAVAAFPNGHPRSAYSSQHVDAL
LAKQAAGATVAITQLFFHADHYLAFVERARRAGVTIPILPGIMPITSPARLTRVLELTGE
ELPGELAIELEIEPTVEGRRQIGIRWASDLIRAVVDGGAPGVHLYAFNQHETVLDVLHSA
GVIPERHLSAASKGTS
>A0A1E3PKC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nadsonia fulvescens var. elongata DSM 6958|TrEMBL
MSKIVDAVKALDPTKPYFSYEFFPPKTTSGTENLYARIERMATFKPMFVAVTWGAGGSTA
EKSLALAAACRNQAGLDVCLHLTCTNMDKEILDSALTQAREHNVKNILALRGDPPRGEEY
WSSSSNEFHHAVDLVKYIKKTHGDFFCIGVAGYPEGHVDGVDTSGQDALKDIPFLVEKVR
AGADFIITQVCYDTSKLIAWEKALREHESGVFNDILILPGLMPINTYQSFLRTAKLSHAS
IPSELLAKLDEIPVGDDDKVKQLGVEVLINMISDIFEKTERRVRGFHFYTLNLEKSVALV
LEKSKVLALSRNELTSLPDASGPAKKTRRSSSLNVDNKIIVDEIREGLKNMDFMANAVDA
GNPNIERTFDDALAISTGEGELGREATWDDFPNGRFGDSRSPAYGEIDGYGPSLHIDNAK
AYKIWGYPVTPEDISNLIIKHICGKIEAIPWSDVSLSPETSLIQEELIQLNEKGYFTVSS
QPATNSSKSNDKIFGWGPKNGYVFQKAFVEFFISANDWRKLKARIDNFEDVISYYASTSK
NGFESNLASGSANAVTWGVFPNREILQSTIIEEESFKAWSEEAFSIWREWQRLYPKGTAS
YKLLDNIFNNYHLVTIVNHDYIDTESLWSVLLE
>A0A0P0IQI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Ndbn-20|TrEMBL
MGSPVMAIDCDSVPDNLVHCFSIEMTGKDIDALQAAAPLLPPGTSVAVTFLPGENYETRI
AACKAVRDLGFEPMPHFSARRIQDEAEFHDFLHAVVAEAKVRRCFVIAGDAAEPEGPYAD
SMQLIASGAFEAAGIDLIGVAGHPEGHPNMTAGEATAVLRAKTDEIERRGMAALIVTQFT
FDAARTLDWLAEVRQAGIDVPVLLGVPGPAGIKTLLRFAARCGVGASASVLSKYGISIGH
LLGSAGPDRFVDALRAGIGEQHGHVRLHFYPFGGLDKTARWIADYARKH
>L3PUR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli KTE75|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A379LL15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter phenylpyruvicus|TrEMBL
MSKPQFSFEFFPTKTDEGITKLYQTFDTLNELAPSYFSVTYGAGGTTRERTLGIVEALKN
RASTPIAPHISCIGDDKSQIAELLDFYKSIGISRMVALRGDLPSGQVGMGELPFAVDLVR
FIREHSGDHFQIEVAAYPEMHPQAISFEQDIQNLINKFEAGANSAITQFFYNAESYLYLR
DALEKRGIDTDKHKLVAGIMPIINSSNLIRFADSCGADIPRFIRKQLADYGDDRKAIREF
GFEVVHRLCEVLIAEGVPALHFYTMNRVEPNKRLVQSLGLTPSSTQA
>A0A1M2ZCE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. 66-10|TrEMBL
MTLSLNQLEEARRALDAPLYADVAGDIDVSFEFFPPKTEKMEETLWQSIGTLAPLAPRFV
SVTYGAGGSTRERTHATVARIARETAIPAAAHLTCVEATREEIDAVAREYWAAGVRHIVA
LRGDPPVAGERYSAWPGGYENAAALVAGLRRLHPFELSVAAYPESHPDSPDAAADLDNLK
RKIDAGATRAITQFFFEPETFFRYRDRVAAAGIAAEIVPGIMPVSNFAAVQRMSAMCGTA
VPAWMGRVFAGLDDLPDARQLVAATLAAELCRKLYAGGVKQFHFYTLNRAELSFAICHLL
GVRAKIGAQAAAA
>A0A2A4C4R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. IDO3|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTDLCRRLIDAGVPGLHFYTLNAASATRTICDRLAG
>A0A7C4M5Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MVQAFSNLMKNILDGKFVYTGELEPHKSMDLSEVISWAKTLKETGKIVAANVTDNPKSVG
SISSLVASYIIQRETGLEIIYQLRCSDRNRLALISDLLGAAALG
>A0A841FJH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytomonospora endophytica|TrEMBL
MTLGAPSVMPGQPPAIGDLVAAPEPTFSFEFFPPRGDKGEKTLWTALRELEPLQPSFVSV
TYGAGGGNRAKTIETTERIATETTLLPMAHLTAVNHSVAELRNLIGHFAAVGVRNILALR
GDPPGDVSGEWIAHPDGFTHAHELVSLLKESGDFSVGVAAFPERHPRSPDWDSEIRHFVA
KCRAGADFAITQMFFNWADWARLRDATVAAGCDVPIVPGVMPVINVRNLERIAELTGAHI
PPAIADRFHAVAEDPVAVRDLGVEIATELCDRLLSEGAPGIHFITMNRSTATREIWQNLR
SVAPV
>A0A1Y1RIA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Cloacimonetes bacterium 4572_55|TrEMBL
MRKQPFLDCLNDHVLLCDGAMGTMLYERGVYINRCFDELNISNFGLIKQIHLEYIQAGAD
IIETNTFGANRLKLSPHGFKKKVKEINYEGARIARAVAQDQVYVAGSIGPLGKPVEPFGS
ISQSEARSIFLEQAEGLVQGGVDLFMLETFGDINEIRQAILAIREICDKPIVAHMTFRNE
GVTLMGVPAETAAISLDKWGADVIGANCGVGPQPVFDAIQRISTVTDKKISAQPNSGEPK
LIDGRVIYMTSPEYYASYAKRFLRAGVSLIGGCCGTSPEHIRRVRAVIKAIRPTSERIQI
QIPKKSEILEARPTSMSEKSELARKVSEGRFVVSVELVPPRGLSTKTIIKRAARLKASGV
DAVNIPDGPRATARMTPMATALLIKKQIDIEVLLHYCCRDRNLLGMQSDLLGMEALNLRN
ILVITGDPPKLGDYPDATAVFDIDSIGLTRMVSRLNHGLDIAGNSIGRQSSFFVGVGANP
AAIDFDREVDRFHQKVEAGAEFALTQPVYKTTYLQRFLERIQPVKIPILVGILPLVSYRN
AEFLHNEVPGMAIPDDIRHQMSQAGSGKQGRDQGVKIARDALIAAKDMVQGVYIMLPMGR
LEMALEVLEAV
>A0A7J3I089|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MMELKLKDSLRKGFTLIGQVNSARTVDVNVVVNAVKSMGKVSAVIVSEPQGVLGAANTAV
VSGVVKRETGMEVICQLTCRDRNRAALLSDVLAAKMLGVDCFLVTDGSHPKTSDIPQAMA
VFDLDSAQLVQMIKHLSEKGETPAGHKAEGQLNLCVGTIAFPAASPIEVEVRRLERMARL
GLDFMVTYPTFSIEALNRFQSETKRLDVPVIVGIRMLQDVRDARRLNEDPRVTVPPELIA
SLEKAETLKGEGKANACLEANLNFFEGFIEAVKSSGFAGCSIHAPGIEQAVSRLVSKLKT
>A0A7L1DEX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serilophus lunatus|TrEMBL
MVNETQHPCSASSSSRSDGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQEAGDRW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELALSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7C0XKH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MSGKVFSDLMSHLKAGKFTFTGELEPEKTTDLTRVIETVNKLKGYVVACNVTDNPQSFAC
ISSLAASYIVQRDTGMETIYQLTCRDRNRIALLSDILGAAALGIKNILALTGDHTILGDT
PQAKPVFDLDSVQLIYMIRKMVDEGVDLNGKEIENPPKLHVGGGVNPNAKPLEPELIKFE
KKVMVGAEFFQTQVVFDIDTVKTFLAEVKKFNVPILIGIFPLKSYGVAEYFDKTVPGVNV
PKELLEKLFKAKDIQDKKKRRMKYNEINLEYFIDFVREIKKTTHAAGCHIMSVGYEEIVP
DLVEAVKAR
>A0A7S9X5Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter concisus|TrEMBL
MLKEKILNKEKGLVLYGLTPPKAEFEESKLRDISERWTGRINDIKADGLVLYEVQDESER
NDSERTFEFSGTLSPEIYYKKYLNVATPSIFYRVASGYGEDEFRTALKAQSSNLNVLVGA
TSSTQKVRLNLARAYEIASEFKELAVGGVCIAERHGKKGDEPQRMREKIAAGAKFFISQA
IFDAQLARKFLEDCAAAKISEPIFLTFSTAGNAKTLEFIKWLGVSVPNSVEERLNLSSDY
LASSCEIIKEIWCELKKFGDENGLNLSINIESVMAKRAEIEASLELTHKMRVLL
>A0A497MM84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MVKMADKRPAYSQLVKDIRAGKFVLTGELEPEKVTGIEEILVSARAMKPYVVAANVTDNP
LAYAYMNSLVPSWKVQEEVGLETVYQMTVRDRNRLALTSDVLAAAYLGIKNILAISGDHT
VLGDNKGAASVYDVDSAQFVYLLHRMIDEGVD
>A0A5M7PXM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. M_5|TrEMBL
MSFFHANQREALNQSLAELNGRINVSFEFFPPRSGEMEETLWRSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRAIAQDYWYNGIRHIVALRGD
LPEGGGRPEMYGSDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMNAMFA
GLDEDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAVAA
>A0A537GZ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MRLSDQARHHNLVTVELIPDRVVPNDLALLRGRVDAITVPALRNGHDDPSYPKSFSITPQ
RRSLASASIINRAGITAVPSLTCRDCSRSDLAAISNQVEQGLGNVLIVYGDPYPEPRPGT
YEFTKTSELIREISSLNDGNDPCIGAVTNQHADKRESEISRTISRVEAGADFIVTNVAFD
SESVLEHRDSLLEAGLNVPLFVQVSIPLSLDNLLFVSQKFDIPVPAHVRKKLLDDATGGS
LAVAAEAYEALRGEANGVHFSYLFRQRNPIPTYRHLLETIGIAGPTLAPIATSPVNTSPV
A
>A0A350VXN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MNLREYITNNRLAADGAFGTYYAEKYGNDELPEAANTMHPERVLEIHTEYIKAGARYIRT
NTYASNSSLLSNDEQKVRENVNAAVGIARKAIGQSGVEEKIYLAGDIGPIPEMSGFSKSE
NESEYTRLASYMLEAGVDAVHFETFADYEEILPAIRYIRDSAEDIFISVCFSVNQYGYSA
AGLSAKRLIADAAKLPVDAVGLNCGVGSGHMAQLMDGLDSFGGKFFIALPNAGYPNFTRN
QMHFGGAPAYFAGKMLDIAKKGADIVGGCCGTRPETIAKVCEKLNGLPRCEKMMADAAEP
EAGQVKKRGFLYDENGELKKKKLIAVELAPPFDANDEKLLESAHSLIGAGVDVLTFPDSP
SGRTRIDSVLMADKVHRETGIAVMPHICCRDKNAVAMRSLFMGSRINDIYNMLIITGDPL
PSMVRETVKSVFNFDSVGLMKIAKEMNEEVFCDSPLCYGGAINQGRKNIEVELGRVKKKL
AAGADFFLTQPVFCEEDVNRLRYIKEETGARILCGIMPLISRKNALFMKNEIAGVNVPDE
LVERYPEKGSKKEGEAVGIELAKQMIALTEDFVDGYYFSFPFNRTYLLKEILN
>A0A7C2ZVQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MSETCISDLMASLKSGKFTFTGELEPGKTTDLAAYVDVAKKIKGYVVACNVTDNPQSFAY
ISSLVASYIIQKKSGLEVIYQITCRDRNRIAIFSDLLGAGALGIKNVLALTGDHTTLGDT
PQAKPVFDLDSVQLVHMIRRIVDEGVDMNGKPIESPPKFFIGAGANPNADPIEPELIKFE
KKVRAGADFFQTQVVFDIEKAKNFLEETKRCNVPVIIGVFPLKSYRVAKYFDENVPGVKV
PEDLMEALAKASEISDKKLRKLKYKEINLEYFSSFIKELKKTTSAAGCHIMSVGYEEIIP
PLVESVK
>A0A7J3F249|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MSGAAISELMASLKSGKFTFTGELEPGKTANLSRHIEAAKKIKGYVVACNVTDNPQSFAY
ISSLVASYIIQRETGLETIYQITCRDRNRIAVFSDLLGAGALGIKNILALTGDHTTLGDT
PQAKPVFDLDSVQLIKMIRQIVNEGVDMNGNPIESPPKFFIGAGANPNANPIELELLKFE
KKVYAGADFFQTQVVFDIEKAKNFLKETSKYNVPIIIGIFPLKSYGVAEYFNKNVPGVKV
PEDLMALLAKANEIADKKMKRAKYNEINLEYFSNFIKELKRTTPAAGCHIMSVGYEEIIP
LLVESVK
>A0A497MCI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MIVVRPKPLEEILEFLHGRRNILIVGCDGCTTPPRGLREAQTYANLLELAGKLKGENFNL
KATTIPKTCDSRIAYSSLVGQLEGVEAIVSLACGIGVQVLNEVFPEVQTYPGNDTVFNGM
EVREGGIFEERCMACGSCLLGETGGICPVTMCAKGLLNGPCGGFFDGKCEVGGWVNDCGW
VKIFDRLKQLGRLDLFTKIRLPKDYRDMQNPRRLSLEEAATKKAIPPLIDEVKEPGKRPA
YSQLMKKIRNGEFVVTGEVEPVKTTDLSEVLKAAETLKEYVTAINVTDNPTAFAYMNALI
PSYYIQEKVGVEAVYQMVARDRNRLALTSDLLAAGALGIKNILALSGDTTTMGDNPQSKR
VWDLDVTQFIYMISKIVDEGVDLAGNEIHNPPKFNIGSSANPCATPLEPEIYKLVRKQNA
GAEFLQTNSLYDIEIIKHFLDECRAAGLKIPILIGITPFKSVKMMDWLVKYVPGVVVPDE
IQEKLRKAREKSKEAFVEMNIEIFSELCREIRKTTRAAGIHMMAIGFEWVVPKILEGAGL
K
>Q30PY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas denitrificans (strain ATCC 33889 / DSM 1251)|TrEMBL
MFDELINKLKNDTYITLETTPSHSPIFSPIIETIAKLGLDKLVDGFTTTDNPLAKLKYNS
LFAAKMLQDRFEKPVIATMSMRDRNKIALQSDLLGSNEVDVRAILALTGDPATISDQPHT
KGVFEADSTLLLDIIACFNSGINYAGKPLAHQPREIYPFAVINSYAKNPKTLQKKMQKKI
KHGALGIITQPVYDIENAKLLLELKDAANTTCNNENKNAELILGIFPITKLRTAQFLSAH
VPGINVPDKWIELLREAHEKGSDEEYRVGFELSRNLFLDLKKLHPKIHLMSANQFQLAHD
ILI
>A0A1H1G806|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermostaphylospora chromogena|TrEMBL
MSLGRPSVHPARVPTVRELLAAEGRSFSFEFFPPKTPEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVEIVERLAHETTLTPVGHFTAVNHSIKELRHLIGRFADAGVRNILAVR
GDPPGDPMGEWVPHPEGVRYAEDLVRLIRQSGDFCVGVAAFPYKHPRSPSVESDTEYFVR
KCRAGADFAITQMFFRAEDYLRLRDRVAAKGCHTPIIPGIMPVTQMSTIARSEQLSGAPF
PPELAERFEKVASDPAAVRRLGIELAAELCAKLLDEGAPGIHFITFNRSSATREVFQLLQ
PVPATV
>A0A1I0PFT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. khp7|TrEMBL
MSVTEFIHQDKSCRRFSIEVLPPLKGTGTEKLFADIDKMLELNPAYINITTHHSEYVYKE
LDNGQFERQRIRRRPGTVAIAAAIQQRYNIPVQPHVICSGSTIEEIEYELLDLQFLGISD
VLLLRGDKAKEDSRFVPTPGGHAHTTELMKQVKRFNEGFFADGTPIKRPGKPFAYGVACY
PEKHEEAPNLEMDMQYLKEKQELGAQYAVTQLFYDNEKYFAFVEKARQMGITIPIIPGIK
PFAKLAQLTVVPKTFHCDIPEALAKEVVKCKTDEDARQLGIEWTTAQCKELYGHGVNNIH
FYTVSAVDSVIEVAKRL
>A0A397MB21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. AG209|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAARLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELINFI
RDEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
AKLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A350WHV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNRYNVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>I1RYW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)|TrEMBL
MLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIAELTCE
MVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDKWEAAD
GGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATFIVTQM
FYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDALEPVKN
DDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPSADRPLQHAL
PWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDAYGIGL
TGSNEANRKKWGEPKAIQDIAELFVSYLNNKIESLPWSESPLTTEADEIRDDLIELNKRG
LLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHPDLTYY
AVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDWAHCYD
ISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPVANGAV
DTEPIANGTAVTAAAN
>A0A261TWQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella genomosp. 5|TrEMBL
MLLNQVDMRTSVRDITEACSLEVSAKDIPALTAAADRILPGTTLSIPYLPGQDDATRLAA
ARAVRDLGFTPMPHLSARRIGSAAELESFVALAAARAGAERCFVVAGDPATPLGPFADST
SLIETGVLERSGIRVVGVAGHPEGHAFMSETERWAVLERKCRAIARRGMRPEIVTQFGFD
ADIVLAWLVTLRARGIDFPVRVGVPGPAGIAVLARYAALCGVSACASMWSKYGISLGKLF
GTAGPDVFVDRLAAGLTQAHGEVSLHFFPFGGIAQSLKWIAQYRGRAESMRAAASSR
>A0A3C0MIX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKIRELLELDKTTLSFEVFPPKKDMDFANVEKAAFGIAQLQPSYMSVTYGAGGSTKGHTI
RLAGDIQKKFNVPTIAHLTCVCATKESIEQALSQMKEAGIENILALRGDVPKDFNGNAFT
DFSHASDLVKLIKENGDFCVGGACYPEVHPDSASKQADIEGLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRVREAGIAVPIIPGIMPITRQVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLMANGVNHIHVYSMNKPQVAKGIQDNLSEILKVVD
>A0A353N3T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MITAGTEIAHRAAKDKEVFVAASIGPIPDMVGDTDLDQALITDEYKFLVDIFLKQRVRIF
IFETFSATTYLQKITGYIKEQDDTVFVLTQFATTPEGFTRKGINVERIVAEVKKIEEIDA
YGFNCGVGPAHLFNTLRNIKGIDFATEMVAVAPNAGYPEIINERTVYIHNTSYFAEKMKA
ISNLGIKILGGCCGTTPAHIEQIINVVKPAPVTVHPNRRRVRITVSPQDERETRNFLRAG
KKNQLVVAAELDPPFNADVGTIIKNAHICKDNGVDIVTVADSPMGRARVDSLMLAAKIKR
EVGIEVLPHICCRDKNINALKSSILAGYIENIRNVLAITGDPVAVADKNDIKAVFNLNSF
KLIEFISIMNKELFADDPIKIGGETY
>A0A6P1E383|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus hilgardii|TrEMBL
MSLTALFNDKTVFSLEVFPPKKDSPKEAILPTLQQLQSINPDFISVTLGAGGSDHYTGTV
SIADLIQNQLNIPAVAHVPGLYQTESQVLNLLDHLSEINVKNILALRGDKIPGKEPVGVF
NHANELVSFVHKNRPDFSIASACYPDCHAEANGFIDDIAHLKEKVDAGADHLISQLFFDN
QSFYDFKEKTEIAGINVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQDSKQA
MKDAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWDATKSVFEAANQKKTEKASNH
>A0A7C5Z7L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MRLPEIYAHRRPAISVEFFPPKTPAGEALLAQRLERFRALDPAFCSITYGAGGSTREKTL
EWARRLRNEYGFETMCHLTCVGHSREELRSLLEGLWADAIENIIALRGDPPRGQENWQPH
PEGLRHAVELVRLARSVAPFGIAVAGFPEGHPESPTEQEDLRYLKEKVDAGADVVITQLF
FDNTDFFHYVNAARAVGVSVPIVPGIMPFRTGAQLEKFTTVYARTRNGPARIPEKLRKRL
QGIASDEDAARLGIAYAIEQCEELLDRGVPGIHFYCLNESDAVDAILQSLRSSHRLA
>A0A6L5YGT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Waltera intestinalis|TrEMBL
MGNTKHTKEQIRERIQQKKLLFDGAFGTYYGGKYDTKQLPELANLEAPERVKEIHTEYLE
AGAQILRTNTFAANSFCMDRSKEQIEETLRSGVRLAREAVAAWRARTGETKEVYIAGDIG
QIPGDALAQKDTLCRKYEEICRIFLEEGVDFFVFETFSEMEELLPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGAIKEIDAVGFNCGVGPSHMYRILQTLYKPADKFLTALS
NAGYPQMVTGRMIFTGDNREYFVDRMQQMIALGVDMAGGCCGTTPEYISDLAGKLDFTQY
PQTQEKAEPEKKQAGTEDHSFYHNKEAEGRKKLIAVELAPPAGIDDEKLMDAAHLLQRSG
VDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGIH
NFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFAQAPVSYGGAINQGRRNLE
VEIGRVKKKMAAGATFFLTQPISTKESADRVRRIKEETGARILCGIMPFVSLKNATFMKN
EMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVITMTEDFADGYYFSFPFNRVTMLEK
ILD
>A0A0S7LLK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poeciliopsis prolifica|TrEMBL
MVNQVQQVDGSWQSCRGDSSGNSSGESSKESSRCSTPLLDADRSDRLREKMRKRMDSGDQ
WFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVN
YCGLESVLHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGDDWEDEEGGFNFAVDL
VKHIRSEFDEYFDICVAGYPTGHPEAESYEQDLQHLKEKVDAGADFVITQLFFRADTFLK
FLDDCRAVGITCPILPGIFPIQGYQSLRQLVKLSKLKVPEEITKIIEPIKDNDAAIRNYG
IHQAVDMCRVLLDSGKVPGLHFYTLNREVATLEVLRQLGLWVEDPRRPLPWAVSANPKRK
VEDVRPIFWASRPKSYIYRTQDWDEFPNGRW
>A0A1C7FNQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor plautii|TrEMBL
MMDIRTYLSKGKPLLFDGAMGTYFAAHPGRAEERCERANLTRPEEILRIHRAYLQAGCRA
IKTNTFAISGDLSDGNDETACDIVNAACRLARQAAQPYGAYVFADLGPAPCDHSRAPADL
YQTQAQWFLEQGVTHFLVETLSGDEGLPELAGWLKKKNPDAFLMVSFAVDHSGMTSAGRL
GSELYRFTSELAGVDAVGFNCVSGPRHLLKYIQTLELSDKPLTVMPNAGYPTVLGRRTVF
GGQPGYFAGQIAQIVQAGASIVGGCCGTTPEHIAQTAQALKEPLPKCTVSAPKKLLKPAA
NASNSLWEKLEAGKRVIAVELDPPVDDDSAGFWEGVQALRGSGADAVTIADCPIGRPRAD
SSLLACKIKRDIGIEPLPHMTCRDRNLNATKALLLGLSMEGVHNVLVVTGDPIPTEDRNE
VKSVFNFNSRKLARFVHMLNENTLRTPFRIYGALNLNARNFDVELRRAQEKEACGVSGFL
TQPVLSAEALDNLKLAHKTLRGKILGGIFPVVSHRNACFLNNEISGMRVCDEIIHLYEGK
DRDAAEALAVTVSTAIAKEIFPYTDGYYLMTPFRRVALMEHIIQNIQQSRIS
>C5E2N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)|TrEMBL
MRVSEKLQKNREANGTSKATFSFEFFVPKTSQGVQNLYDRMDRMYQTHPQFIDITWNAGG
RLSQLSTELVSTSQSVLGLETCMHLTCTNMPRQLIDDALQKAYESGCQNILALRGDAPIT
SSEWKPCEGGFTYAKDLVRYIREKYGDHFDIGVAGYPEGHPEEEASPKLVQYLKEKVDAG
ADFIITQMFYDADNFIEWCRQVRAAGIEVPIIPGIMPITTYAAFLRRSSWCQINVPEAFM
AKLDPVKDDDQAVREVGTELVAQMCQKLLDSGYVTHLHMYTMNLEKACIMVLDRLGLLSE
DEDIFRDEVVPMPWRKSLHPQRRNESVRPIFWQKRPYSYVARTSQWTADEFPNGRFGDSS
SPAFGDLDLLGSTSIRQSPQRALELWSTPTKFSDIAALVIDYLHGKLKCLPWCDVALNHE
VDTTMPQLLDLNKHMILTLNSQPRVNGASSADKIVGWGPNNGYVYQKQYLEFLLPKSKLS
QLRDFVNDMPSLTYFAVDSADELHSNHPDDTAANAVTWGIFPGREVLQPTIVEKVSFLAW
KEEFFDILDEWKRIMGENNHSESVALLESVISDYLLVNIVDNDYVSDGDRIYDMLQRLY
>A0A2N9JIY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micropruina glycogenica|TrEMBL
MSVNPEGAEREYLPSIAELLADTSRPTFSFEFFPPADAAAGDVLAQTILDLDATGPDWLS
VTYGASGATRDRTIAATRFIKARTEAQTMGHLTCASQSTDELLATLAAYADADVRHVLAI
RGDMPGGPTVPWQRHPDGLANATELVRLIADNFGFGIGVAAFPDPHPQQRDADLDARLLL
AKQEAGASFAITQLFFDADAYLRLVERTRAVGCTLPIVAGIQPVTNIGQIERFATLSGAS
MPEAMVQRLHAVAHDPAEVRRVGVELATELSVKVLQGGAPGLQFFTLNRSRATSAILANL
RALGLDRRSPAAASDE
>A0A1S1HQQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia stuartii|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRTEEMEQTLWKSIDRLKNLKPKFVSVTY
GANSGERDRTHSIIKDIKEKTGLIAAPHLTCIDASRDELKEIARDYWNSGIRQIVALRGD
LPDNSSKPDMYAADLVELLKTEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPSWMSKMYE
GLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>I0UQH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia aeria F0474|TrEMBL
MTTVHPALSYELYPPRSHASCDSLLKTITELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLALRGDIPPENTRPLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAARLAGVQMPIIPGIMPVTSLTRLTKLCELAGLEVPRELAHRLETASDS
RELHRIGVEHALNQCRKVLDAGAPGLHFYTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>A0A379GWM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia stuartii|TrEMBL
METALSFEISAMSKIDNTLEHLLKNTEELTPLFYTVNTEIGKTEWRDTYNTCCELKNLTH
VNVVPHIAINNKDECELCFIIKEYLKNDITELFVIRGDRHRFDEELPFNYGIELIDFIRR
RYPEVMIKSSIYPDYHKESITPEIEIDWLRKKLQLGVTELISQLCLNKNAFSYMKKQLGN
DIPITISMMPMLNFSFIESFFKNNAIDYPLWIKKHIRPSNINNHRAFGIQLTQFLIGEYI
KENKRLHFFTLNNAEMVKKLFDKLR
>A0A7Z0RWC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas salicampi|TrEMBL
MSRQEHPLGISFEFFPPNTDAGREKLMHTRDQLAARNPRFFSVTYGAGGSTQARTREVVR
EVGKSGITTAPHLSCIGSEKAQLRDLLAQYREEGIDSLVALRGDMPSGMASIGELRYANE
LVEFIRDETGDYFEIAVAAYPESHPQAPHLDKDVENFARKMKAGANMAITQYFFTADAYF
HFADKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSDAIAAF
GTEVVSRLCQRLLEGGAPGLHFYTLNQAAPVLKIVDNLG
>A0A838LD25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. CGMCC 1.13656|TrEMBL
MVDSQARRIGDLVRSGERSFSFEFFPPRDAAGEEQLWQAIRELEPYRPTFVSVTYGAGGS
TRDTTVRVTGRISRETSMTAMAHLTCVGHTQAELDGVLDAYAEAGIANVMVLRGDPKEGP
RAEWTPTEGGFTYAEELVTRARQRGGFSIGVAAFPEGHPSAESLDHDADVLVAKARAGAE
FAVTQMFFRAEDYFGLVERVRARGCDLPILPGIMPILNLANIRRQGELIGTDVPASVVDR
ILAHDGDAVAMRAAGIDLAAELCEELLEGGAPGLHFYTLNRSKATREIFARLNIAA
>A0A7Y8LYS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MKSGSRLERTLEAGHFAFTGELGPPQGANVEAVRKKASYLKGIVDAVNITDNQTAVVRMS
SWGAGLIAIQEGLEPNYQMVCRDRNRIAMQSDILGAYAHGIRNMLCLSGDHQQFGNHPMT
KGVFDIDSIQLISMVKGMRDDKKFLNGDEIDGAPQMYIGAAENPFAEPFEWRVHRLAKKI
AAGADFIQTQCIYDMKMFRDWIRQANDMGLTEKVHILAGITPLKSGGMARYMAKNVSGII
IPDEIIDRIVQAKKAAEEGIKICVEQIEELKEMKGVHGIHLMAIEWEHRVPEIAERAKLI
PRPQV
>A0A1J1AC64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halodesulfurarchaeum formicicum|TrEMBL
MTRQDFRAAVEADDRFAVTWELIPGRGSHEPQQEEVFEDAETAASGDVVDAVSLTDNPGG
TPALSADYLGMKLKERGIEPLVHFTTKDKNRNQIEGLLHALEREDIHNILIMSGDHQGPA
FEGQAKAVYDLDPVQTLDFVSDLNDGFEFEDNFGRHNELAETDFFPGAVVSPFKRLEAEL
MPQYWKLEMKVEKGAEFIIPQVGFDARKFHELIKFIDEKDLDVPVIGNLYVLDPGSARAM
NENRIPGAIVTDDLREEVEAEQEGEDPHQAMLERAAKMYAFMKGMGFAGVHIGGHAADYD
DVEYIVERGEELAPDWEEYVSEFDFPMEDGFYYYERDPETGLNADEHAILPENPSTGLKY
KGFKVAHELMFEPDGPLFGPMRWFSKKVDDSALEEPFTTFERVTKTISNDCQECGNCALF
DMAYLCPMSQCPKNERNGPCGGSYDGWCEVYPGEQECIYVRAYRKLKADGGLEKAREKLR
DTYIPPPDYDLEGTSSWLNYYLGRDYAGKRVGNEVADD
>A0A852G4L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Larus smithsonianus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A4R8FN64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas xianhensis|TrEMBL
MSAQEHPLGISFEFFPPNTDAGREKLLHTRDALAERNPRFFSVTYGAGGSTQARTIHTVN
SVRECGINTAPHLSCIGSEKAQLRDLLNQYRDNGINSLVALRGDLPSGMGGIGELRYANE
LVEFIRAETGDHFEIAVAAYPEAHPQAPSFEHDLQNFVRKVQAGANLAITQYFFSADAYF
HFVERAQALGVEAPIVPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDIESIQAF
GEEVVSNLCQRLLEGGAPGLHFYTLNQATPTLKVLDNLK
>A0A354YEW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium|TrEMBL
MTALSFEFYPPKTDEQRTQLDRTAAKLKPFSPEYVSCTFGAGGSTLSYTSETVRHLNQKH
GFQAAPHLSCVGGSREEIRELLKLYRAIGCRRIIALRGDLPSGMGHPGDLRYASELIGFI
RAEHGDAFRIEVGAYPETHPQATDALSDLKYFKAKVDAGADAAITQYFYNADAYFHFVDA
VRRLGVDIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIAKRMQAYGDDAESVRAFGADVV
AQLCQRLVEGGAPALHFYTLNLAKPTSAVLARLA
>A0A0P7Z2K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. HL-48|TrEMBL
MSRHEHPLGISFEFFPPGTEAGRDKLIQVRDELAARQPRFFSVTYGAGGSTQARTREIVR
QVSESGVSTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRDETGNHFDIAVAAYPESHPQAPNLDRDVENFARKMKAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKIVDNLSG
>W7PRJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. BC04|TrEMBL
MGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSESIAAFGEEVVSRL
CQRLLDGGAPGLHFYTLNQATPSLRVLDNLS
>A0A1V6UK07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium coprophilum|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEAAENGFCYAKDLVKYIRNKYGNHFDIGVGGYPEGADDNTDVDQLIDHLKEKVDAGSSF
VVTQMFYDADNFIEWLKKCRAKGITVPIIPGIMPIQTYASFIRRSNWTKVKVPPQWMEAL
EPVKNDDSAVRDIGKTLIADMCRQLIAAGIKHLHFYTMNLAQATQLVLKELDLSPSEESP
IQRALPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISNIFVDFLAGKLDRLPWSDSPITTEAHDIQEDLLK
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKND
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCHDAASPSRKLIQQVMDDWYLVNIVDNDFHRSDGLFELFDGLEVKELNAEVEVPEKVEV
PEKPLTNGHTEQNGVAAN
>A0A436WQC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M4A.F.Ca.ET.020.02.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMT
>L0G2T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Echinicola vietnamensis (strain DSM 17526 / LMG 23754 / KMM 6221)|TrEMBL
MKVTEHLNQAKKTLFSFEILPPLKGQSLNEMLDGISPLMDFNPPFIDVTYHREEYVYKKH
ANGLLEKVSTRKRPGTVGICAALMNRFKVDAVPHILCGGFDKEETENVLIDLNFIGVENV
LALRGDAPKSEGRFIPEEGGHSYSNELVQQIVGMNQGKYLHEETESGFQTDFCVGVAGYP
EKHFEAPSFKFDLKYLKAKVDAGAEYIVTQMFFDNQKYFEFVKQVREAGITVPIIPGLKP
ITTLRQITVLPSIFFLDLPDPLMDELEKCKDNAAVRQVGIEWAIQQSKELIDFGVPCLHY
YTMSKASTVHKVASAVF
>A0A0C3MXB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. cp20|TrEMBL
MAFHHAQHANSLNQSLSELNGDINVSFEFFPPATPEMETILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETDLVAAPHLTLVDASDEELVELAKHYWNSGIRDIVALRGD
LPAGSPKPTRFANDLVRLLKSVADFDISVAAYPEVHPDAPNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSIPSWLHRQFE
GLDDDPSTRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A2G0QEL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus hominickii|TrEMBL
MSFFHANQREALNQNLAELDGQIRVSFEFFPPSTAEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKEKTGLDAAPHLTCIDASRDELLNIAHDYWESGIRHIVALRGD
LPNSGCKPEMYGTDLVELLKKEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATLTNVRIPSWMTRMFE
GLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A3R7TN02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED57|TrEMBL
MSQTDRSNPLPTLSFEFFPPRESGSVAKLLDGTVTKLAAFDPDYCSVTYGAGGSTRQGTQ
DLVGALLAAQINAVPHLSIGGSTDAALLELVEHYRNIGVTKILCLRGDQPSGDASRPVYA
KDXVERLQQHYPKHFELAVAAYPEVHPDASCAANDMIHFSAKVSAGASSAITQYFYNPDA
YGFFLDRCAKAGLSIPVTAGIMPITNVEALQRFXAKAGADIPRWLAKSMATYXSDEKGLI
DYGVEVVTKLCERLLEMGAPGLHFYTLXRWGASSRICRNLGFLER
>A0A6A6B343|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aplosporella prunicola CBS 121167|TrEMBL
MHISQKLAEGQKNGKPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPTFIDITWGAGGRNS
HLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDDALKQAYHAGCKNILALRGDPPREKEK
WEATAGGFRYAKDLVKYIRDTYGDHFDIGVAGYSEGCDDQDDPELLLEHLKEKVDAGGTF
IVTQMFYDVDIFLDWVKKVRAKGITVPIIPGIMPIQTYAAFMRRANWTKCNIPQDWLDAL
EPVKNDDAVVREVGKGLVATMCRRLMDAGIIHLHFYTMNLAQSTRMVLEELDLTPDVESP
IEKPLPWRQSLTPGRREENVRPIFWRNRNRSYVVRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNDQNIKTWGKPKSVKDVANLFVAYVEGKLESLPWSEQPITSEADDLKPDLVN
LNQRGLLTINSQPAVDGAKSSHPIYGWGPRNGYVYQKAYLEVLVNPELIAELITRIERDP
ELTYYAVNKSGDLKTNAPGEGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEFYRLGQDW
AQCYTSSSPSRYLIEDLMDTWYLVNIVHNDFHDSKGIFELFDGLEVPDVEKQPHGAEEVQ
VNGGGPVNGVSKPLANGATNGANGANGATNGEARVPDTIVNLESTSAIQKGAESTAEPKH
ETEAGWAKKE
>A0A7K3A3L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8379|TrEMBL
MALGTASTRTDRARRVSDMLAPGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHITAVEHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWIAHPEGLTYAAELVELIKESGDFCVGVAAFPSMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFDPEEYLRLRDRVAAAGCDTPIIPECMPVTSVRMLERLPKLSNADF
PPALKERILTAKDDPAAVRSIGIEFATEFCAKLLDEGVPGLHFITLNNSTATLEIYENLG
LHDQQA
>A0A8J5EBB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yarrowia sp. B02|TrEMBL
MKISHKLEKAHAADSAPTFSFEFFVPKTSQGVQNLYDRMDRMYQLGPQFIDITWNAGGRL
SNLTNEMVATAQSALGLETCMHLTCTGMPKQLVENALQSAFDGGCQNILALRGDPPVESE
KWEAVDGGFRYAKDLVKYIKSKYGDYFDIGVAAYPEGTPEEPDVDVLIDHLKEKVDAGGT
FIVTQMFYDTDNFLKWVDKCRAKGINVPIIPGIMPISTYASFMRRANWCQIQIPQAFLDK
LEPVKDDDMRVRELGTQLVADMCQKMLDSGKIKHLHFYTMNLEKATVMVLERLNLPAQDS
AVAPLPWRPSLALGRQDETVRPIFWKNRKQSYVARTQDWDEFPNGRWGDSRSPAFGELET
YGVLLRQSPQKVLELWGEPTSVDDLKTLLVNYLNGKLASLPWSDVPISNEIDSIKPQILE
LNNRGILTINSQPAVNGAKSTHPVHGWGPKNGYVYQKAYLELLVTPEIAAKLVNKLENQS
EITYYAVNKTGNLQTNAPGGPNAVTWGIYPGKEVIQPTIVEKISFLAWKEEAFRLGSEWA
RCYPAESETRKFLDDIFNNWYLVNIVHNDFHDATGIFDLFQDL
>A0A853F022|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thiodubiliella endoseptemdiera|TrEMBL
MKTSFEFFPSRTDKGQQTLAQVRQKLSLINPEYFSVTFGAGGTTQDATLETVLDIQKNDG
ISAAPHLSCIDSKKDNITALLDQYKSAGINRIVALRGDIPSGVRDIGDFHYANELVEFIK
TQYNDYFHIEVAAYPEMHPQAKNIQTDTAHFVNKVKAGADGAITQYFYNADAYFRFVDEV
QKLGIDIPITPGIMPITSHTQLVRFSNMCGAEIPKWILERLKLYENDLNTLNIFGTEVVI
ELCQTLKNQGVDSFHFYSMNRAQPSLEIAKTLL
>A0A7Y0C0V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp|TrEMBL
MTVAVSFEFFPPKTPEGAAKLRLTRQDLYGFKPEFCSVTFGAGGSTQEGTFGTVGEILAE
EVDAASHFSCVGASKTTVREQLAALRAMGVRRLVALRGDLPSGYGMGGEFHYASDLVAFI
RAETGDAFHIEVAAYPEIHPQAKSAAADLQAFAAKVKAGANSAITQYFFNADAYFRFVDD
ARRLGVDEPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTDSIKSFGLDVI
TALCDQLCTAGVPGLHFYTMNQSAATAEILRRLQPV
>A0A084DN30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. MSh2|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLQPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGADV
VTGLCQRLVDAGVPGLHFYTLNTAAATRTICERLAG
>A0A1H8GNT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loktanella fryxellensis|TrEMBL
MTRPRISFEFFPPKNLEGSFRLWDCVNVLAPLGPEFVSVTYGAGGTTRQLTHEAVTTIDK
TTGLKVAAHLTCVDATRAETLAIAEEYAAAGITDIVALRGDAPKGAATFTPHPDGFASSV
DLIAALAETGKFTLRVGAYPEKHPEAASQDADVAWLKRKIDAGAVAAITQFFFEADTYFR
FRDTCAAAGITAPIIPGILPVENWKGAARFAAATGTHVPPALAAQFEAAVADGTADQLAT
RHATDLCTALVAGGVDHLHFYTLNKPQLTRDVCAALGIGPDPRLQSVA
>A0A1F3WTA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RBG_16_56_24|TrEMBL
MTRQLFSFEFFPPQTPEGAEKLAATRKQLASLKPEYFSVTFGAGGSTQNRTLETIRQIHA
EGHSAAPHLSCVGSTRENIRNMLNTYRDMGIKRIVALRGDLPSGMASIGEFQYASELVAF
IRAETGTHFHIEVAAYPEFHPQARSAQDDIHNFKRKVSAGADSAITQYFYNADAYFRFVE
ECRKLGITLPIVPGIMPIVRFAQLARFSDACGAEIPRWMRKTLESFGDDNESVQAFGLDV
VTQLCERLLAGGAPGLHFYTLNQAGPSLEIWKRLGL
>E1V538|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)|TrEMBL
MSAQQSPLDISFEFFPPNTDAGRDKLMRARDALATRDPRFFSVTYGAGGSTQHRTLSAVK
AVRECGIDTAPHLSCVGSEKAQLRDLLKRFQEDGVKRLVALRGDLPSGMGGVGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFERDLENFARKMHAGADIAITQYFFTAEAYF
HFVDRARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAF
GEEVISGLCQRLLDGGAPGLHFYTLNQAEPTLKVLDNLRT
>A0A1F1L752|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC04H06|TrEMBL
MVPRISASAPLDQNELQVYSAPAPQRTALSFEVIPPRHDADAAKVNGLLEALSSYHPDYI
AVTSSQRSGWLRGTAAFIERIAQRTQMRPLAHLACTAGTRAELIGWIDALVDAGVRGLLA
LRGDLAPGQTSLPEGYLPHADDLVRLVREWEQSQAARFAAGRLAVGVACYPQGHAESRNA
DEDIDVLLTKQRCGADFAITQLFFDAVDYHRFAECAHLAGVNIPLIPGIMPMTSAKRLAR
MGELTGLPVPAPVVNRLAQARDPAEEHEIGLELTAQLAREVLAGGAGGLHVYTHNNAAVT
QDLLDRVGIAAA
>A0A1W9U391|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterium sp. 4572_20|TrEMBL
MSFQKRLVAGDFVVLAEFDPPKGVDASDLVSNLIKIKGRVDGVIVPEMAQAVMRMSAMGG
AALMEQHGMETIMQICSRDRNRLALQGDVLAAYFLGIKNLLVVPGEEIMYGDHIDAKQFA
DIDELTLLRAIKGLQNGVDMAGMELKGSPKFLTGCSIKPAKNEIALEAELELTQKKVKEG
AQFLVTPPVFNINAFTYFMEKAKGLGIPVIATVFLLKSVGVARYISTNVPGPPIPEEMIS
RLRKAPDRINECINIAGELITSLKELCQGVQLVTMGWENRLPAILDAAKI
>A0A1M7LYP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus flavefaciens|TrEMBL
MHIKELFKDKTVFSFEVFPPKKTSPVEVIYDTLNELNDLRPDFISVTFGAGGSGNSRYAL
EIASKIKESGITPMLHLPCINFTRSEIDAALDEAKQRGIENILALRGDINPEIPPVNDFN
HASDLITYIKSKGDFDIAGACYPECHPDAETLVEDIINLRKKVDAGADHLITQLFFDNDN
FYEFREKAAIAGINVPIEAGIMPVVNKKQIERMVTTCGASLPTKFVRIMTKYEHNPEALR
DAGIAYAVNQIVDLVASGVDGIHLYTMNNPYVARKISEAVSGIIKT
>B5HCL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces pristinaespiralis (strain ATCC 25486 / DSM 40338 / CBS 914.69 / JCM 4507 / NBRC 13074 / NRRL 2958 / 5647)|TrEMBL
MALGTASTRTDRARTVRDMLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVAPNFVSV
TYGAGGSTRAGTVKATQEIAADTTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDEDTRHFVD
KCRAGADYAITQMFFVPEDYLRLRDRVSAAGCETPIIPEIMPVTSVKQIERFATLSNAHF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHEQS
>A0A7C2FFS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSITESYAESRPVISFEFFPPKTEAGYRTLFRTIEDLKQLGPGFVSVTMGAGGSTRSKTV
DLTIEITRKIGLETMCHLPCTGFRPQEVDRILDQLEEGGVHNVLALRGDPPRDDPDWRPP
ADGFQYANELVEHIARRGGFSIGAACCPEVHPESPDAATDLAHLKRKVDAGADFLISQMF
YDNRHFFHFEEQARAIGIEVPIVPGVMPIASVSGIRRMAGINGTTFPEELDADLERVDGD
EQATYELGVRWARRQCEELLERGVPGIHFYTLNKSPATREIYRSLFG
>A0A6G1AYM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocuta crocuta|TrEMBL
MVNEPRGDGGPTPRSEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRH
IRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLQVPQRIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLTSGLVPGLHFYTLNREVATMEVLKRLGMWIEDPRRPLPWAISAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMW
GEELTSEESVFEVFACYLSGEPNQSGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A6M0R9X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium niameyense|TrEMBL
MDIRKIFEQKKLVFSLEVFPPQNKLPVRTIYKTLNELNHLNPDFISVTYGAGGSTINNKT
SEISSLIKNVYNIEPLAHLTCISSTKKDIDDITNRLKLEDVSNILALRGDNNGPEKKDFN
YASDLIKYIKHKDKFNIISACYPEGHIENKDIDLEIKNMKRKIDSGTTSFISQLFFDNNH
YYDFLNKVRSKGINVPIQAGIMPVINKRQIERVSSLCGAKVPSKFIKIMNRYEHSSEALM
EAGIVYAVEQIVDLISTGVEGVHLYTMNNPYVASRISDNIKIILESINREKVS
>A0A7C1W837|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MIMTRSSPLNLAAGDPAAVFPPPGDVEVSFEFFPPKTEKMEQRLWDCIRRLAPVKPTFVS
VTYGAGGTTRERTHETVVRIRNETDLEPAAHLTCVDATKDEINEIARRYWDQGIRHIVAL
RGDAPQDDGAYTPHPDGYAYASDLVAGLKGVADFEISVAAYPETHPEASSPEADLDNLKR
KIDAGAVRAVSQYFFDPDVYFRFLERVRAAGITVPIVPGILPVTNFSQVTKFSGACGTSV
PGWMHGMFSGLDDDPETRNLVAASVAAEQCRVLHAGGVKEFHFYTLNRADLVYAICHILG
VRPEPPSQPREDG
>A0A6C1P6H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneolaceae bacterium|TrEMBL
MKVVELYDKAKEPLISFEIIPPKRGGSIQTVFEALDQVMQFNPPFIDVTSHAAEAYYEEL
GDGSMKRHIKRKRPGTIGLCAAIKHRYNVEPVPHIICKGFTREETEDALIELNYLGIQNV
LAIRGDDPGSPKPHHKNRETNEYAVDLVRQIRRMNNGVYLENMLEASKTDFCIGVGGYPE
KHIEAPNMNWDLMRLKEKVEAGADYIVTQMFFDNQYFFDFERKCREAGITVPIIPGLKVI
TKANHLTMLPKIFHLNIPIPLSDEISSNPDRAREIGIEWCTRQCAELLDAGVQGLHYYIM
SNPSPVVEVINRLPVSGFSNAFTTGK
>A0A243LZI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis subsp. jegathesan|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2A4V870|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MKLFRHIAARHSGLYLFFYKVTERIILFLRPVFMWVGLSRLEGPFVLLERATKGFLFDCK
MCGQCLLSSTGMVCPMNCPKQIRNGPCGGVREDGFCEIDAQMKCVWVEAWTGVKKIGGQE
TFTIPLRPAETNQQGSSAWARVIEKNKDADELYRVKVFPPASLEVGPHRRPSGILEERLQ
AGDFVVTAELSPPDSADPAEVIQRVAPLKGLVTAVNVPDGAGANCHMSSLASSVILHNDG
IVPVMQYACRDRNRIALQGDILGATALGVTNLLCVTGDSVQAGDQKGAKPVFDLDSISLL
RTAKMMRDEGIFLSGRQLKDSPNLFLGAALNPFVSPIEARVLRMERKINAGAQFFQTQFC
FDIIALKKFMTEVRARGLHKKCYILVGVGPLVSAKAAKFIKSSIPGVTIPDHIIDRLERA
GDERQEGKKICIETLNQLRQIEGVSGVHLMSYRKERLLAEIISESDIMG
>A0A523FP45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTIGFHNDNKSAPVKVSFEFFPPKNEQMEEALRAAIDRLEPLSPAFVSVTYGAGGSTRER
THATVKYIQNDTSLNAAAHLTCVGATREEVDDVIRSYWQAGIRHIVALRGDPPEGVGTQY
VPFPGGYENAADLTAGVKRIADFEVSVGTYPEKHPESLSLEADIELLKQKVDAGASRAIT
QFVFDSEIIARYRDKVMAAGLDIPIIPGIMPINSFKGIKRFAAGCGATIPDWLSNLFDGL
DKDPLTRQMVAGAVAIEQCLTLREYGFDQFHFYTLNRADLTYAVCYVLGVRPNS
>A0A379UZG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MRPRRTLTCIDATRDELRTIARDYWNNGIRHIVALRGDLPPGSGKPEMYAADLVGLLKEV
ADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAV
ST
>A0A3M2FSA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp|TrEMBL
LLEQTITALAELRPDFVSVTCGAGGTGHEGTRDLVVEWTRRFDFPVVAHLTCVGFGRDEV
ARLLDDYAAHGVIAVLALAGDPPADGSPPRGDYRHAIDLVHDIRRHEADFVVGVAAHPEG
HPRSPDLASDRRHLAAKLALADFALTQFFFDVDVYTEMVADLDRAGVDRPVIPGVFPVTA
PATVRRFAALNATRVPEALFAELEAVTGEERRRLATAHAAALAGALLERGAPGLHLYTMN
RAPVAAEVVRRLGLRPGPAG
>A0A2W4TEA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTANIASPPAPTLADARALLLSPLGPVARAGENANPVRVSFEFFPPKTDEAEANLWKAVR
RLEPLNPDFVSVTYGAGGSTRERTHRTVQRILAETTLKPAAHLTCVEASRDEVDQVIADY
KSIGVDHIVALRGDPPGGAGIGGAYEPRADGYANATELAQAIQRIGGFQTTVGAYPEKHP
ESPSIEHDIDVLKAKVDAGATRALSQFFFDIDAFLRFRDRIRAAGVTIPLIPGIMPVSNF
GGLQRMSVSCGASVPAWLAAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTL
NRADLVYAICRVLGVREQKASA
>A0A1G6JYC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces prasinopilosus|TrEMBL
MLAAGKTTYSFEFSAPRTPKGQRNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVHETEQ
IVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPTADWVPHPQGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSAEWDTDVAHFVDKCRAGADYAITQMFFHPE
SYLRLRDRVHAAGCETPVIPEVMPVTSVKMLERLPRLSNASFPDALKERILAAADDPAAV
RSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPRA
>A0A537KZQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MMSDSERASRHVGRPRIRVSFEFFPPKTEEMERTLWDSIERLAPLRPNFVSVTYGAGGST
RERTHATVKRILSQTALTPAAHLTCVSATCGEVDDVIRAYHDAGVRHIVALRGDPAGGAG
EKYAPHPGGYENGAALVAGIKRITDAEVTVSAYPEKHPDSASVDADIDMLKAKVDAGASR
AITQFFFENDLYFRYLDRVRARGIAVPVTPGILPVQNFKQAKGFAERTGASVPDWLAARF
DGLDDDPATRKLIAAAIAAEQVLDLVDRGVSDFHFYTMNRADLVYAICHLLGLRPAPKQE
AAE
>A0A2D8G6T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MEKQKQTSLSVHPFESNDLNISFEFFPPKTDKMAETMWQSIKRLEPLSPRFVSVTYGAGG
TTRERTHQTVQRINAETTLSAAAHLTCVGATREEVNSVAQDYWQSGVRHIVALRGDXPDG
NCYSPYPGGYDYAVDLIXGLREVADFEISVAAYPETHPQALSAEDDIDNLKRKIDVGATR
AITQYFFDVGVYLXFVERARKAGIXVEIVPGILPVTNFAQVVXFSAMCGTKVPDWMQXLF
EGLDGDPDTRRLVAATTAAEQCRLLRAEGIDAFHFYTLNRADLSFAICHILGVRPCGDYA
>A0A1H8IN14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rubidus|TrEMBL
MALGTSSTRTDRAVTIRELLAGGGRSYSFEFAAPKTDKGERTLWNAIRRIEAVQPTFVSV
TYGAGGSSREGTVRATDRIVSDTTLTPCAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGAWVPHPQGLTYAAELVRLIKESGDFCVGVAAFTEMHPRSTDPAEDTRYFLE
KVHAGADFAITQMFFDADAYLRLRDRVDAAGCTIPIIPEVMPVTNVRQIERFSQLGNAPF
PPELASRILAVQDDPAAVREIGIEFTTEMCRRLMAEDIPGLHFITLNHSTASLEIYENLG
LHQRAA
>A0A2W6VWF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp|TrEMBL
MPFSDDTYACPCTHDHEPTLLSFEVMPPRKPSLEEPFWKTVDELLRVRPDFMSVTYGAGG
KDRSNARSTVHRLVRDTPIQPIAHLTCVGNSTEEVVSTVYDYLDSGVRTFLALRGDPPVG
QEDWEPGPGGVGSATELIHLIRTVEKRRCDAHPGEALRSAFKPLTIAVAAFPAGNPAAGT
TPAQEVERLLVKQAAGASFAITQLFWDADVYASFVERARRAGVTIPIVPGLLPATDPARL
RRVQDLTGIEVPEYLLTTLADYPHQDARDEFGAVFGSRLIHSVLEAGAPGVHLYTFNRSK
PVLDILALMGVEPDPLRSGASAPEARA
>A0A3B8W7G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium|TrEMBL
MKVIDLIQQSTKTAFSFELLPPLKGNSIDKVYSVIDRLKEFDPKYINITTHHSEYLYKEQ
PNGNIQKVNIRKRPGTVAIAAAIQNKYGITAVPHIICKGFTKEETEYALIDLNFLGVYDL
LLLRGDANKLEAGHIQPGQSHDHASDLQIQVNQFNKGIALDNSTFDRPNTPFSYGVAGYP
EKHEEAPNLDSDIAFLKQKVDQGADYIVTQMFFDNQKYFDFVERCRKEGITVPIIPGIKP
VTVCNHLTVLPKIFRSDIPEDFATELRKCNNDAEAKQVGIEWCTQQCRELIEYGVPSIHF
YSLMATDSVYQVAKEIY
>A0A6L5XUL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Velocimicrobium porci|TrEMBL
MKIADILKKKMTFSFEVFPPKEKQPIEPLINTLNQLYQFQPDFVSCTYGAGGTNVGRNME
ICHEIKKAGMAIPMTHFTCISNTREGIKRELEEYISKGVENVLALRGDIPSGWEDTRGDF
QHANQLIAFIKENFPDMGIAAAGAPEKHIQCDTFEEDIAHIRMKQDAGADFIMSQLCYDL
EQFERWVEMLRKAGIHLPIVVGVMPVLNKEATLRMTLSMNGCSIPRELAEIISRYYNNPE
DFKKAGKEYTIKQIFRYMNLGVNGIHIYSLNKYEDVSEIVQGAGWRKNLDQKVILR
>A0A7W7YF66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecobacter vanneervenii|TrEMBL
MHIADILQSQRPTLSFEFFPPKTAEAFEALYQTIGELEAFKPSFVSVTYGAGGSTRELTH
DLVVRINTTTSLDAVPHLTCVCHSEADIAAILERYAQAGVSNILALGGDPPKNLAGYDRS
KDAFQHAADLVAFIKKFNDSGAHPDKRGFGIGVAGFPEGHPATPNRVLEMDYLKAKVDAG
ADYICTQLFFDNHDFYDFRERCHLAGINIPIIAGIMPITSASGMRRMAELAAGARYPAKL
LRAIQRCGNDEAAVQKVGIHYATEQCRDLLDHGVDGIHFYTLNKSHATREIYSSLGIRDS
AAVRPHS
>A0A2E8S4Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MDVASLYRNAPGGLPFSLEILPPNRGLGLNNIHDFFNNLHEWLPAFVSVTYHQAHKIDII
DDNGQMEQIWNRKKPGTLGVCAMLKFQYGLNVIPHVICGGFSKFESEDFLVDLDYLGLKH
VLALRGDPNKTETQFNPHPQGYAYANELVEQIVDMNAGKYVEDVKEARPTDFQIGVAGYP
EVHAEALNLHDDVTNLKRKIASGASFVITQMFFDNACFFQFDKICREMDIHVPLIPGIKV
ITSKRQLEVLPEIFGTKLPKKLVHDVMACETDEEVCQVGIAHAVNQTKELLEYGVVGVHF
FTMNNSQVFNQVLQQFQE
>A0A534JND2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MRSGSRLERVLASGAFAVTAEIAPPASADATEIRQNAARYRGAVDACNVTDCTRARVQIS
SLAAAAIVLQEGVEPVMQMVVRDRNRIALQADLLGAAALGIRNVLCLWGDPPSAGNEREA
KGVFDLKTEEMIETVRNLRESGTLRGGDTVETRPRVFIGAAADPFRGSKEESFGKLRAKV
MAGADFVQTQGVYDVAAFEEWMRLVRKEWLHEKVYILAGVIPLKSLKMARFMEDKLGAVV
PKHIMDRMEKAPNPKAEGVSIAVRTIKALKKIEGVRGVHIMPVGWDGVVSKVLKDAGLAP
RPDLPG
>A0A534KEG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MMAVDAGSRVMRAGSQLEKVLASGGFAVTAEIHPPASADPSSIERQAATYRGLVDACNVT
DGQRALVRISSLAAATLVLQSGIEPIMQMVLRDRNRIGIQSDLLGASALGIRNVLCLWGD
PPTAGNEKDAKAVYDLTTEEMIATFRVLRDAGTLRGGDAVQVPPKVFIGAAADPFRGSKE
ESFAKLRAKVSAGADFVQTQGVYDVDRFEDWMRLVRKEWLHEKAYILAGVIPLKSPKMAR
FMVEKLGAVIPKQIMDRMEKARNPKAEGLSIAVGT
>A0A2Z2HWH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natrarchaeobaculum aegyptiacum|TrEMBL
MSSEIETTPTAEGLLELLEEPRFELMPFESMDEQLEHLPEGAEVAITTSPTLGLESTIEW
TERATDRGFEVVPHVAARYVRDVDHLKDVAARLTDAGVSDIFVPGGDREEPAGEFTSAYD
LLSTLEDLDYEFEDVGITGYPEGHDFLDDDVLAEAMAKKEPYATYIVTQLCYDPEAIIDW
TDEIRARDVDLPVEVGIPGVMKYQRLLQISRKVGVGDSIRFLQKTSGVLGFLRELVGSRG
TYVPDELVEGLAPYATDPHYNIRGVHVYAFNQVPDLESWRSETLTQHR
>A0A1F3YJM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RBG_16_66_20|TrEMBL
MHAARLWSVRHARGLSRAYGLFARLAPRLAPLARLLGRAGAEAAVRPIERAAKQFLFDCR
MCGDCVLSATGMACPMNCAKQLRNGPCGGVRPDGGCEVIPQMRCVWLDAEEGRKRIAPLA
VAPDAAIAPLDHTRSGRSSWVPVIFPEAAPSAAPRTDPGIAHPREAFERACADRFVVTVE
LAPPDSAAPAGFLARAARFRGLVDAINVTDGAGGNCHMSSVAASALLAAHGDIPIYQVAC
RDRNRIAIQGDLLGAAALGVQNILCLTGDDVSQGDQPEAKPVFDLDAVTLLGIARRMREQ
GAFASGRKLEAAPNLFLGATANPFAPPFHERVANLERKVDAGARFIQTQFCFDLERMAAF
MREARARGLHQRCTIIAGVGTLGSAAALRRMAQRVPGVHVPEAVLQRIGQAADQRAEGKR
VAIETIQALARIEGVGGVHLMGYRNETVLAEIIAESGLRGRVQAPAAGTTG
>F9ZPE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus caldus (strain SM-1)|TrEMBL
MATRCEFSVEFFPPKNPAGEAKLRETIGALQALRPDYASVTYGAAGSTQEPTLATVAMLA
RDTELEAVPHLTCIGSTEAGIRAILEHYRELGIRRIVALRGDLPPDREDPGFFHQALDLI
AYIRAFGGFQIYAAAYPEFHPRAVHARADLEYLQRKVEAGASGLITQYFYNPDAYLQLRD
DLARRGVDVPITVGVMPMTNYAQIANFSAQCGAEIPQFLRRRMESFADDPGAQAELAIEV
ASRQCRLLLDQGAPGLHFYTLNQAEATLAIARNLGL
>A0A662U4P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MKLTDMFETSRFVVTCEVEPPKGVNVHKSLEKAEKLRKYIDAFNVTDNQRAVMRVGSLAM
CKLLKEKGLEPIYQLTCRDRNRIALQSDLLSAAVLGIENVLILTGDHTSMGDHPEAKPVF
DLDSVSLLRAAKMLKNGYDMAGNKLDGFPELCVGAVATPGIEPFELHMIKLQKKIREGAQ
FIQTQTIYEPEIFEKFIDALKESNLRVPVMLGHVMLKSAKMARFMNKNIPGVRVPEGIIR
ELDGLPPDRLVEKSISISIDLINEMKHRCQGVHLMPMGWEKHVPRVVEAIRK
>A0A1F9TEJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium GWC2_64_44|TrEMBL
MKFTERLKTGKKVYSFEFYPPKTAEDTAKLFTNAVELLKLSPDFVSVTNSSSGVTPYRTV
ALCGVLKAQFGLEVVAHLTCLAHTRTEIAEILSGLKKMEITNVLALRGDPHNVEAGARRR
DYNYAAQLIADLKAAGGFAIGGACYPEKHPEAPGLEADIARLKEKVDAGAEYLITQLFFD
NDCYFRFLEKTAAAGINVPVLPGLMPVTSYKQMQNFTKLMKVCIPEALRAGIERWEGDKD
GMFKFSVEYASAQAEALLKGGAPGLHLYTLNRSRAAMAILKNVKGEALK
>A0A366ZME5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus sp. TF02-6|TrEMBL
MRHGRTTGSVSSATVTPTVRELLADARPTWSFEFFPPKTPDGATQLWTALRELERLRPSF
VSVTYGAGGSTREGTVSVTERIATETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLL
ALRGDPPGADPQAEWVTHPEGLAYAAELVELIRSMGDFSVGVAAFPEGHPRSPDPDSDVE
MFVGKCRAGADFAITQMFFRAEDYLRLRDRVAARGCDVPLIAGVMPVTNARQITRIVQLS
GQAFPEDLAARFAELDGDRPEDRAAVRAYGVEVATELCRTLLDEGVPGIHFITMNRSTAT
REVYANLAAVGATH
>A0A1I3NJC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parapedobacter indicus|TrEMBL
MSNINNLSKFGGCLVRLNEMKVTEHIKNAKGKTLYSFEILPPIKGQSIQSIFDAIDPLME
FNPPFIDVTYLREDYIYKQHPNGLLEKVAYRKRPSTVATCAAIINKYKVDAVPHLICGGF
TKDETENALIDLQFLGIDNVLVLRGDARKSDSSFIPTPGGHAYASDLLQHVVNMNNGRYL
HEDMENSEKTDFCIGVAGYPEKHFESPNLSTDFQYLKMKADLGADFIVTQMFFDNSKYKA
FVDRCRENGIHIPIIPGLKPLTNSKQLVSLPKTFHLDIPLELSEAVQACKSEHDVREVGV
EWMIEQCKELKAMGAPVLHFYTMGNPKPTKRIIQAVF
>A0A4Y3HVY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio inusitatus NBRC 102082|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLVAAPHLTCIDASRDELITIADDYWKNGIESIVALRGD
IPPGGGHPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIVPGILPVSNFKQASRFAAMNHVKVPGWMAQQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQKVTV
>A0A142VVU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis terrae subsp. terrae NBRC 15098|TrEMBL
MTTSLDALAEARRAAASPLFANLEGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLAPRFV
SVTYGAGGSTRERTHATVARIASESAVPPAAHLTCVEASRGEIEEVARAYWDAGVRHIVA
LRGDVPGGGAYRAHPEGFANAVELVAGLKRIAPFDISVAAYPEVHPDADCPQADLDNLKR
KLDAGATRAITQFFFSPEAFLRFRDAAAAAGIDAPIVPGILPVSNVSQTRRMADMCGTGI
PAWMIALFEGLDDLPAARQLVAATVAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHMLG
LRPVAPAKDKAA
>B6W151|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei DSM 17855|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEAQINDFNKGVFVDGSPIKITGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVEKVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A1F3XXK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionales bacterium RIFOXYD1_FULL_55_31|TrEMBL
MTALPFKADRKLTDVLSETKFTVSAEVIPPRNGSEQGKVLAQIDSLRGAGAQFLAVTKGA
GGSLRGGSLPIAQAIKENFNIPCIAHFTCRDLTAFDVENQLIDHHYFGIRNILALRGDPP
DGQPEWRPREGGYSYAHELIRQITALNRGEYIPRPGGPERDGTATTDFCIGAAVYPEFPD
KMKRLQYFRQKVEAGAQYGITDMLFDPEVYARFLDDCGKAGITIPILPGTRILKSRTQAH
KMMAKFRVNLPSEVLNMLPETATGPEAIPLATELFMRLVERLRSLGAPGIHVFVISDTDA
AVTAIMRCALNR
>A0A3G2G6H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. 3008163|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEATPGGHASAMDLVNQINNLGRGKYLHDDQACDDHNKFCIGVAGY
PEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVTKAREMGITVPIIPGIK
PIATKKHLKLLPQVFKIDLPEDLINAVESAKNNEAVKQIGVEWAISQCKELLDFGVPVLH
FYSMGKSDNIKKVAGELF
>A0A2E1V474|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geminicoccus sp|TrEMBL
MRTLLNLSTEFFPLTSPLPLERLSRTWQSLKAAGVSEYSLTFGALGAGQDKSTTCLKYMR
TYDRKTTPVMHLTCRGQTWKSLERLITRWKRLRVQRVLALRGDAFRPRNDGPNSSVELVA
FLTEHGMKTAVAAYPDGHPDARKAAHEMSETHWLYRKLEAGADQIVTQFSARIDGVLRLR
DAVERFGEPVEMRVGVMPVPDWERFKTLIDRCGIEPDPGEALLFDGLPDHSHHALSLGLA
YANMRALRAEGCTSFHLYGLNDSRLLLPLIRSLQSLDRP
>A0A167KNV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium rileyi (strain RCEF 4871)|TrEMBL
MDKITDKIAALPADREYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
ANKSLELAELCQRELGLTTCLHLTCTNMSKRLIDKALEDAKVLGIRNILALRGDPPRKQE
YHDAEDSEDDGTEDFIWAIDLVKYIRKKHGDFFCIGVAAYPEGHSDESHPQSQSSEHDLP
YLVDKVQAGADFIMTQLFFDIDSYDDFEKTLRQHPSGAFKDIPIMPGLMPIQSYQMIKRT
TKLSHARMPTAIMDRLDAAKGDDEKVKLVGVDIISELIDQIRTIKSRTPGPRGFHFYTLN
LEKAVSFIVERTGLIPEGSDNEEALIIDDGTLAPPPIQVNGNRTSAHSRTSRRHSSVGSD
PYNRVIVAGQPPTHPEWEATAREAGVPADSINSRANTLAISEGEGVLGREATWDDFPNGR
FGDSRSPAYGEIDGYGVSLHMSVTQAVTHWGRPTSREDVIKVFVRHIQGEIPAIPWSEEG
LSPESSTIQSRLVGMNSKGWLTVASQPAVNGVSSSDRTFGWGPVNGFVFQKAFAEFFLPS
ADWHVLADKLKGSDYCDSVCFYAANAKGDFVSSDVGGGVSTRTVAASTNAVTWGVFPGKE
IVTPTIIEEVSFKAWCEEAFGLWEEWAKVYGRGSASEEVLRGIQSDYWLRGTVDVAAWLT
SK
>D4Z7L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium japonicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S)|TrEMBL
MKLALERFPSDRNRSLIKKSRKTRNPERQSDSIGSKPALPGQDAPILDLVRSFSLEMTAK
DVASLADAAPMIPAGTPISVTYLPGETMPARVAAARTVKSLGFVPVPHISARRIPSKDDL
VEFLTVLDGEVGIDRAFVIAGDPPAPMGPYEDALAVIRSGLLDRAGIGTVGISGYPEGHP
DIGREKLDQAMKDKIAALAEQGKRVEIMTQFAFDADAILDWLARIRRDGVAAPVRIGLPG
PASVGKLIRFAARCGVGASARVMVKYGASITRLLSTAGPEHLIESLARQRDPAIHGEAML
HFYPFGALVDTARFIRSHYGDACE
>A0A847JGB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacteriaceae bacterium|TrEMBL
TAEARARAAIDFGMEQVADLLAMGVDRFHFYTMNRADLVTGIVEVLGITPEG
>A0A7C1FNG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilinea aerophila|TrEMBL
MLRSGRFAVTAELNPPDSADPQEVYDAALVLSSVCDGINAVDASGANCHMSSVAICALLT
RAGYEPVYQVSCRDRNRIAIQGDLLGAAAMGVRNVLCITGDDVTVGDQPEAKRVFDLDSI
QLLHTARIMRDFGVFLSGRKLTQPPQFFLGAVENPFAPPLDWRPHRLAKKVAAGAEFIQT
QYCFDVSRFRTFMQRVRDLGLHEKCYILVGVGPLRSVGAAEFMRARVPGVYIPDAVIERL
KGVPKSQQRVEGKRICIEIIQQVREIEGVAGVHIMAYRQEELVAEIVEEAGLLPRPFRND
APPLAHRRHRSARHLPNP
>A0A6P1FFG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. VKM Ac-2759|TrEMBL
MRASRLEIVPTPGVVDRIALSLPRGSAISVTALPHHGIATTVETAIELAGLGFDAIPHLA
ATRIPDRAQLARLLDRLDAAGVQSLFVIGGDGDRASSAFEHGGDLLATIRELTGDRFRLG
VAGYPEGHPQLSVGAGIDVLAGKAPLADFVVTQMCFSPEPILAYLRALRSRGIGLPVWLG
VPGAVRLRRLLGIAARIGVGPSLSFAGKGGNLRLLGRFDAPGFCARLETQAEQARLDFAG
FHVYSFNDFALRAPTTTEHVGETP
>A0A6N8RB85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
G
>A0A1H7BAM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclobacterium xiamenense|TrEMBL
MKVTEYIQAAKKTLFSFEILPPLKGQSLSHLLEGIAPLMEFKPPFIDVTYHREEYVYKKH
ANGLLEKVSTRKRPGTVGICAAIMNRFHIDAVPHLLCGGFSREETENALIDLYFIGVENV
LALRGDAPKSEANFLPNKDGHRYASELVEQIIGMNHGRYLNDETEVGFRTDFCVGVAGYP
EKHFEAPSLNFDLKKLKAKVDAGASYIVTQMFFDNKKYFDFVDKVREVGIDLPIIPGLKP
ITTLSQIVNLPKTFYLDLPDDLLSGLEKCKNNADVKEVGIEWAIQQSKELVAYGVPSLHY
YTMSKADATYRVAREVF
>A0A4D6Y3N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MNEFFQYHQDIIKQKIKNINNSIHCSFEFFPPKNTSLETKLWLTIDKLSILKPKFFSVTY
GANSGERKKTYDIVKQINKKTGIITAAHLTCINSTPSKLKEIAKHYWNNGIKNIIALRGD
TKEKNYKHTMYAVDLVRLLKRIANFDISVAAYPELHPESKNIKLDMINLKKKIDAGANRA
ITQFFFNVDHYLYFRENCIKYGITAEIIPGILPISDFKQLKRFLSMTNVQIPKWMFEIFS
GLDDNDRFTQKVIGCTIAIDMIQKLSSEGVKNFHFYTLNQSDISYSVCHILGLSCGLSCF
>A0A397NPN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hephaestia caeni|TrEMBL
MSLTLSELEEARRALDAPLYADLAGDAEVSFEFFPPKSEKMEATLWESIQTLAPLGPRFV
SVTYGAGGSTRERTHATVARIQRETPLAAAAHLTCVEATKAEIDAVAEQYWASGVRHIVA
LRGDPPREGARFEPHPGGYENAAALVEGLKKRHPFEVSVAAYPECHPDSLSDQADIDNLK
AKIDAGATRAITQFFFAPEAFFRFRDRAAAAGIAAELVPGILPVSNVAQTRKFAGMCGAA
IPPWMDRLFEGLDDHPAARQLVAATVAAEMCRKLYAGGVRSFHFYTLNRAELSFAICHLL
GLRANAGVSVAAA
>A0A265Q6S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierella sp. P1|TrEMBL
MNIKQLFDKKNLVFSFEIFPPKPDYPIETVYDTIEELSVLNPDYISVTYGAGGSVNNNRT
CQLSHLIKDRYNIESLAHLTCIGSSKEYMDCVLEELEEKGINNILALRGDIGSIGVGEFN
NSQELIQYIKQNGDFGVAAACYPEGHIESKKDIDKDIRILKLKEEAGADYFISQLFFDNS
HFYNLLDKAEQKGIKAPIQAGIMPVINKKQIERVISLCGASLPNKFLRIMNKYEYDKLAL
RDAGIAFALEQIVDLASSGIKGIHLYTMNNPYIAKSITNNIEFIVSSINRKKVI
>A0A1H5V6H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas ureae|TrEMBL
MDSQKKFSPTFSFELFPPQTPQGIEKLRFTRQQLAQFNPKFFSVTFGAGGSTRERTFETV
LEIQSEKHVVAPHLSCIGSTQQNIRIILEKYYEIGIRRIVALRGDLPSGMAQAGEFRYAS
ELVAFIRKEFGSSFHIEVAAYPEYHPQARSAQADFENFKRKIETGANSAITQYFYNTEAY
FHFVDSCESAGLNIPIVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLEGYSDDSASIQA
FGLDVVTDLCERLLKAGAPGLHFYTLNSANLTSVIWQRLNLQEYVQ
>A0A0D1P2R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARTLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHIEVAAYPEMHPQARHFEDDLINFVRKAKAGADSAITQYFFNADCYFH
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVQSIQAFG
EQVITEMCEKLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A6P2BVF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trebonia kvetii|TrEMBL
MPPRPRLPKASLASQQARRVSRPTPKIADILKTGQSFSFEFFAPKTEQAEQQFWGTMRRL
EPFKPAFVSVTYGAGGSTRAGTVQMTGAIAEQTELNPMAHLTAVNHSVAELRNVIGSLAS
VGVRNVLALRGDPPGDPNGPWVAHPEGFRYASQLVELVKASGDFSVGVAAFPELHPRSPD
EETDTRHFLEKCRAGADFAITQMFFYPEDYLRLRDRVGRHGCDVPIIPGIMPVTSLRVVE
NSIKLSGCKVPVGLLDQLREADARGDAATVRAIGVDYAAKMCARLLDEGVPGLHFITLNA
SRATMEIYQLLGLGDRGAALASSGSVAPMTA
>A0A8I1JRT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SQVQVPAAPHLSCVGDTKAELRALLAEYKQVGIKRIVALRGDLPSGMGMASGELRHASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEADLANFAHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEELLQGGAPSLHFYTLNQAEPSMAIWNNLQPSR
>A0A097BE12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria ivanovii subsp. londoniensis|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVSIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLQAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLEELKTVLKILRETTDLPVVANVSMHEPGLL
QNGQKLSDALEELIALGADVVGINCRLGPYHMARALETVPLYNHAYLAVYPNASLPEVQE
GKVVYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIKALRNGLKTTKPILEKKVRPLL
ELVPEEAADEDSGVRLLDKVKEGLTILVELDPPRTFDTSKFFEGAKALDKAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIKRKVEYGADYIITQPIYDVNKTVLLKEALQKANINVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMRDAEEQGRANEKGMEIARELIDSICANFHGIYIITPFLRYDLSI
ELTKYVQTKQQVQVATK
>K0NE46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula toluolica (strain DSM 7467 / Tol2)|TrEMBL
MNELKSGSEFKPGNDLKSGSNLEKVLKAGYFAFTGECGPPKGANVRHLKEKFQYLKGNVD
AVNMTDNQTAVVRMSSLAGSALLVEEGLEPNFQMVCRDRNRLAIMSDILGAYALGIRNML
CLSGDHQTFGNHPEAKNVHDIDSMQLISVVKKMRDEEKFINGEEIDVAPRMFIGAACNPF
ADPYEYRVYRLANKIEAGADFIQTQCIFNMEKFRDFMKKAVDMGLHERCYILAGVTPMKN
AGMANFMSKFVPGMDIPDSLIKRLKGVDKRDQAEEGIKFALEQVEEFKQMEGVSGVHMMA
IEWEHKMPEIAERAGMLPRPAV
>A0A5P1R4K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREHHFVCVMEFVPKASAERFAAMQAIMDRAQLCGWPMTVAIGDRVGSPLDMS
PLDALASFDRPVPALPHFSGKDRERHHLLAQLQRMEAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPLWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQAAPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMREMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGIHDLKQLLALEARLAYWQTHVHTLEQWAPA
WQASWQMPGLPAVTFHPPQANWRQGESRVDASFKEKARYHLMHGMHGLLFSRRNSLSKAF
GWAVRQPLWTTRLGAQVLHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGSALNRCEFGDRECIHSIKYRTAKAVGQTAVLRERLIPCIEEQTRHRSSWPQWFAPPSP
RRVSPQPAPRTQPES
>F5RLH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Centipeda periodontii DSM 2778|TrEMBL
MTQERIDIREHIRKEPLVFDGGMGTYYAQRTHTRGKGVELANIETPLVVEEIHTEYLRAG
AHAIKTNTFAANRIVYQGDTPLVEGILRTGWTLAARAAEPFGAYVFADIGPVTGLPPADI
VEEYRFLSDIFLAAGARHFIFETNSSAEGLVETAAHIKQICPEAFVLTSFSAFPGGYTRD
GFFIEELVRVVTESGYIDAVGFNCVSGVQSMKELVHLLGACSLPLSLMPNAGHPIVIDGR
TFYESAPKYFGEGLAALVRDGVSIVGGCCGTTPEHIRALCAALADRGHASEDAGAWQTRT
ELVPSRSPFFDALKAGEMPIAVELDPPDTGNADKFMAGARELQAAGVSAITIADNPIARA
RMDAAMLAGRVHRSLGLEPIPHMTCRDRNLNAIKSILLGLSAEGVHNMIAITGDPIPTAE
RDEVKSVYQFNSRKLSAFITNLGERGDVVPFHIFGALNVNSQHFPSQLGLAKKKMEAGMT
GFFTQPVLSARAKENMRTARDTLPGALILGGIMPVVSERNARFMESEISGIHVEERIINA
YHGLDRAEAEELAVKLSLEIAKDIEPYIDGYYIITPFARTALVARIVAGIKARRSGQ
>A0A2N1RXI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetae bacterium HGW-Spirochaetae-5|TrEMBL
MKSGSNLERVLKAGHFAVTTEFGPPKGTDLSIVKNKAEFIRGNVDAVNVTDCQTAVVRLS
SIATSAILVQMGIEPVMQMTCRDRNRIAIQSDIFGASALGIKNMLAISGDHHSFGNQKNA
RKVYDIDSMQMISLVKRMRDEQKMLSEDKPFQGEVPMFIGAAANPFAPPVEFRAMHLRKK
IEAGADFIQTQSIYDVDKFRQWMKIVCDMGLDRQCAILAGLTPLKSAGMARYMADNVPGM
QIPESLLTRMAGVPKERAAEEGIRIFCEQVEQIREIPGIAGLHIMAIEWEHRIPEITERA
GLLPRPVMQGNDFFSGDPQCR
>A0A4U2F3H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. F13|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPNFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A1F0PYM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC074C01|TrEMBL
MSPRLSASAPLDQISEDTPKELKRTALSFEVIPPRHDADAAKIDRLLATLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTEEELVGWIDTLVDAGVRGLLALR
GDLPEDGMPEGHLPHADSLVRLIRRWESDRVARLAAGRLAVGVACYPNGHAESATLDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTKVLDQLAAATSPEEEKEIGMQITAKLAKSVMNAGADGLHIYTHNNPDITTDLL
HRIGVIP
>A0A511R3Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meiothermus hypogaeus NBRC 106114|TrEMBL
MKISTLLQSARPVFSFEFFPPKTPQGEVALFRTLHELKPLEPGFVSITYGAGGSERSKTA
EWAARIQNEVGLVAMAHLTCVGSTREELRAILQEYARVGVQNIMAVRGDPPKGVRAFQPV
AGGFRYASELIAFIRAEFGGTFAVAGGGYPEGHPEAASLEADLQNLQRKVDAGLDFVVTQ
LFFNNALYFGFVERARRMGITVPIVPGLMPITDLAQIRRFMDMCGASIPGPLLSRLEKAQ
TPEEVLEIGVEHTTRQAQELLAAGVPGIHLYTLNKSPATRRVMQNLQTVLR
>A0A1W9GWR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium SG_bin4|TrEMBL
MESQKKFAPAFSFELFPPQTPQGIEKLRLTRQQLARLKPKFFSVTFGAGGSTRERTLETV
LEIHAEGHNVAPHLSCIGSTRQNIHSILDRYYQAGIRQIVALRGDLPSGMAQPGEFRYAS
ELVAFIREEFGSAFHIDVAAYPEYHPQARSAQFDFENFKRKIENGANSAITQYFYNADAY
YHFVESCEAVGVNVPIVPGIMPINKFSQLVRFSDSCGAEIPRWVRKKLEGYGDDSESIQA
FGLDIVTDLCDRLLNAGAPGLHFYTLNSADLTSIIWQRLQLSSRAL
>A0A1V9ACE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora piscinae|TrEMBL
MRVRGARERGSARWPAVLAPGLAAPRYEVLPLPGVLDQTGALPAGTTVTVTASPSRGLDA
TVALCEKLAAQRLRAVAHVAARQIRDRAHLHELLDRLAGAELDEIFVVAGDAAQPAGPFA
DGLTLLREIEDSGRRPRRVGVPCYPEGHPAIPERRLWAALLAKQRHADYAVSQLCFDAAV
VCRFLDTARERGVRLPVLVGLAGVVDAATLLRVGSRIGVGDSLAFVRANRAAVAALVRPA
RYRPERFLSELGARVAAGARAPGGLHFYTFNRVTATAEWVAATRAPG
>X6C3U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNJC372A00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A550C3J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Auriculariopsis ampla|TrEMBL
MKLSAKIKQHKGQHPFFTFEFFPPRTDQGFENLVPRICRLSNLHPLAISITWGAGGSTKE
RTLELAGVTQEQNGLDTVMHLTCTNMKVGMVDEALSAAKQRGIESILALRGDPPRGQEEW
TPIDPRFQHGIDLVRYIRASPYASTFSVGVAAYPDGHTERLNDEDKEIGYLKQSVDAGAD
FIMTQLFYDVDNFVRWVKKVRAAGISVPIIPSVMPIQTYATFIRLTKLCGSRVPDSVMSA
LEPIKSDDRLVKDYGVELAVEMVRRITTESDIPGIHLCTLNLEKSVTRVLETLQWTPAHA
PVHNKLIADTPGDVLHPSPQTDNLDLVITPETATDKATVGLKDIPATGCQVGSGELNNAA
SWDDFPNGRFGDVKSPAYGELGPWGSFGQTYTNPLAHLGHPTTLDDLTHIFVDYLDGRIP
TTPFSPTSLSPESRPILPELRALTARGWWTVGSQPAVDGVSSSDEVVGWGPRAGYVFQKC
FVEFFCEEADVQRVARAAEERGEGWVDWFAGNYKGECRGNIPENGRNAVTWGVFPGQEIV
QTTIIERESFCSWKEEAFGIWSDWASFYRPDSEERKLLEDVRDRRWLVSVVHHDYKNPGA
LWEFLKGVGEDDGTL
>A0A4S0ZX29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.156.01.1.1|TrEMBL
MTGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHEDITETQVDMVK
TAH
>A0A2P9HP61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ochrobactrum] soli|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKSEEMEQRLWETVTRLAPLQPEFVSVTYGAGGSTR
ERTIRTVARILKETDIKPAAHLTCVDATREEVDRVVREFADLGVSRFVALRGDPAAGIGE
KYVPTTGGYLNGADLVGGLRQIADFDISVSAYPEKHPESPDFATDIDMLKRKVDAGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPAWLAERFD
GLENDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPYAICHMIGIRPKTEAVL
EPA
>A0A1H2ITV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula phenolica|TrEMBL
MKLSQKLGKNFVITTELGPVKGVLADESLEKARDYLPLDGINIHDCPMGNLRINSISMAS
LIQNSLDVETVPHFTCRDRSLLGTQADLLGAHTLGIRNILVTTGDPPKHGPYPSKAVYDY
NTVDLIRLIKKMNNGLDYNEKEFGGSTDFNIACTAMPTSRKPEHEMEKMEKKISAGADFF
QTQVVYDSEKAVTFLKAARKLDKPILIGVMPLKSVKMARFMDKNVEGIDVPEDVISRMEN
QGATGIEITCDFIKDIIEYADGIHIMAMGDVKGTNHIIEFTRSLIAQ
>A0A8C4HC42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dicentrarchus labrax|TrEMBL
MLWSARVTTARDVAAACPELHGVRGPAQRCFGASNSGGESSKDSSRCSTPVLDADRSDRL
RDKMRKRMESGDRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDK
ETSSMMIASTAVNYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADW
EEEEGGFNYAIDLVKHIRSEFDDYFDICVAGYPTGHPEAESYEGDLRHLKDKVDAGADFV
ITQLFFRADTFLKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIE
PIKDNDAAIRNYGIQQAVDMCRLLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRR
PLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYL
FYLKSKSSKDALLQMWGEELINEESVYEVFTCYITAQPNSRGHKVMCLPWNDEPLAPETN
LLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTAL
LKVLKKYEPRVNYHIVDVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVADPVSFMYWKV
RWRPECCHGSVKVWGAFYQYEVVLSDHLYPMIKYFYPYGSGLFQDCNAPIHRVRAH
>A0A8F9RNI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. LJ668|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYRNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICSAIQHKYSVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEATPGGHSSAMDLVNQINNLGRGKYLHDEDQICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKARKMGITVPIIPGI
KPIATKKHLKLLPQVFKIDLPEDLINAVESAKNNEAVKQIGVEWAITQCKELLDFGVPVL
HFYSMGKSDNIKKIAGELF
>A0A847D2Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus flocculiformis|TrEMBL
MKIREMISKGEPTVSFEIFPPKSSYALETVFDTLTELKDLHPDFISVTYGAGGTAQSNTV
EIASRIKKDFGIESIAHLTGCTSTKEGMKRTLTSIKDSGIENILALRGDIPQEKLADKNW
NPEYRYASELIDDIKAAGDFSIGAACYPEGHVDSINKVDDLKNLKKKMDHGADFMITQLF
YDNDLFYQFKEKLDLVGIEQPVIAGILPVLNIKQVKRIQEISGCNLPPKFLRILDRYAHD
PASLQEAGIAYAVDQIIDLLSSGVDGVHIYTMNKPDATRRIMENISCVRKAVCRKEPQR
>A0A7K2FGG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4985|TrEMBL
MTGKDVSRLEEAAPGIPPGTRINVTYLAGEDPGTRLAAARAVKRLGFVPVPHISARRLPS
RAHLEEFLAGLAADGTGEHVFVVGGDPARPEGPYEDALSVIRTGLLQRHGVRHIGISGYP
EGHPDLTGPVLWSALTDKAAALGAEGFGGEVITQFGFAVDPVLTWLEAVRARGIRLPVRV
GVPGPAGVRRLLGYASRFGVATSASVARKYGFSLTNLMGTAGPDRFLDELALRYDPERHG
VVKVHFYTFGGLRTTSEWVGGYRTAV
>A0A7L4Z2J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HF10|TrEMBL
MALGTASTRTDRARTVRDMLAGGKTTYSFEFSAPKTPKGERSLWTALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVAHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVEAGCDTPVIPEILPVTSVRMLERLPKLSNAQF
PDVLKERILAAKDDPAAVRSIGIDFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHHPPQA
>V6I2E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira alexanderi serovar Manhao 3 str. L 60|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTPDGDLKLMETVKELAHLDPDFVTVTYGAGGSTRDK
TAQILSEISKSYSFPTVSHFTCVGANQDQIFKTLKEIRSSGIVNLMALRGDPPKGEGEFK
KTEGGFENATELISFIRSEKLDFCIGGGCYPEKHPNAKSLEEDVKNLKRKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A1U7GW68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fischerella major NIES-592|TrEMBL
MLIFMLDTQNPTSLTSFRTAAKAGQFLITAEVAPPKGGNPEHMLKMAATLKGRVHAVNIT
DGSRAVLRMCPVVASAILLQHGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALTGD
PVKAGDHADCKGVFDLESVRLLQVIQKLNHGVDYNDKPLNDGALDLFPGAAVDPQCPSWS
GLQKRFERKLEAGAQFFQSQLITDFEILEKFMDKIAADCGKPILAGIFLLKSAKNALFIN
RCVPGVNIPQHIIDRLAQAKDPLEEGMKIAAEQVQIAQQLCQGVHMMAVKREDLIPQILE
MAGVTPVNQMVSL
>A0A1Z4BWG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylovulum psychrotolerans|TrEMBL
MHTQKHHPQLFSFEFYPPKTPEGTASLQLVQSQLAERQPDFFSVTFGAGGSTRDKTFDTV
VDIQTKGIAAAPHLSCVASTKHSIRTILQDYQDNGISKIVALRGDLPSGMMSAGEFRYAN
ELVGFIREETGDHFQIHVAAYPEVHPQALNATEDFKNFKRKVEAGANAAITQYFYNAEAY
FYFIDNCAKHGIDIPIVPGIMPISQYTQLFRFSEMCGADIPRWMRKKLESYGDDRASIQA
FGLELVTELCQRLLDNGAPGLHFYTMNQSALTLAILDGLR
>A0A316BKV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWR4|TrEMBL
MKIVDILKQDKMSLSFEVFPPKKETSFESVKNATESIAALGPAFMSVTYGAGGGVSQYTL
EIAKNIKQKFNVPMLAHLTCVSSSKETVKQRIDDMKAAGITNVMALRGDLTPELIANGRT
DCDYQHAIELVRELKESDGDFCIGAACYPEKHPESANQREDIQHLKEKVDAGADFLTTQM
VFDNNLFFNFLYKLREAGVTCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGILRNVSAILGRNFIA
>A0A3M8ENB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium|TrEMBL
MPYTLTFREKLESERFVVTAEVCPPKGCDCGEFLEKAQALRGIIDAFNVTDNQGANMRVS
PLAPAALLIREGIEPILQLTCRDRNRLALQSELLAAAALGVTNVLALSGDYISFGDHAGS
KPVFDLDSVQLLQTIAALNEGRDLSGAPLRGATSFYAGAAAAPEAEPFDLTLPKLAKKAS
AGARFFQTQAIFSPDHFPRFAEATRPFGAKIIVGILLLKSAGMARFVTKHIPGLKVPPEL
IAELEGAERPLDAGVAIARRLVAAVRPHCDGVHIMAMGKEDVIPDIVADITHK
>A0A1Q5PTT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchananella hordeovulneris|TrEMBL
MSTKLLFTGPRPRPLVSFEFFPPRRSGNLSLTWAGIDKLLAAAPDFVTVTYGAGGSTRSQ
SVDVWRHIRHSTSVPAVAHLTCIGTTRDQLAQTVRDLLQLGVRSFLALRGDLPQGATPAT
YTPGVDELNRAVQLVELIRDTAAACLPDPREVSIAVAAYPGPDSPRFANDLAALRDKVAA
GADYAITQVFLEASHYARLREQAAAVGVQAPLLPGFVPLTDARRVQRVAELAGIEVPTHL
AAALCIANPRDRLRAGLRATLDLIGQTLAAGAPGVHLYTFNRPRPSLDILEYLHATRFLS
CPADRDVVEDLVEATLDTLTPVG
>A3PAM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus (strain MIT 9301)|TrEMBL
MKSKLQQTLEKRSKVITAELMPPRGGSPIRSLKIAQLLKDKVHAVNITDGSRAVMRMCSL
AMSKLLLENGIEPVMQISCRDRNKIALQSDILGANALGIRNILCITGDSVKAGDQHDAKA
VHEFESVRLLEQIQAFNQGIDPTLGELSDKKTSIFAGAAADPSCKNKRSLENRMRKKKEA
GAGFVQTQMVMERQNLIDFCEQISNPLEIPVIAGVFLLKSYKNALFINKYVPGANIPENI
LNRLKNAKNPLQEGIKIAAEQAHDFINIADGVHIMAVKAEHLIPDILEKADISLEY
>A0A416F5D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF32-12BH|TrEMBL
MKIRDILAKNEPTLSFEVFPPKTEDKYESVEAAAFEIAKLNPAFMSVTYGAGGGTSQYTV
NIAASLKAKGVTPLAHLTCVSSTREKVHSVLNQLKAEGIENVLALRGDIPKDGKVEKDYR
YASELIAEIKASGDFCIGAACYPEGHVESANKTEDIQHLKEKVEAGCDFVTTQMFFDNNI
LYNYLYRVREKGITVPVIAGIMPVTNVAQIKRICSMSGTYLPARFKAIVDRFGDNPAAMK
QAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNSLSEIIR
>A0A8E0MAB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei subsp. paracasei Lpp7|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A7H8W7N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. LPB0248|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAVDLVRQIKDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASKVF
>A0A7X2M627|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. BIOML-A2|TrEMBL
MKTTEIFKEHTVLSFEVFPPKRTGAVDTIYSTLEELQKLHPDFISVTYGAGGSENCKATL
EIASAVKNNYHIESVAHLPCIGLSKEDVLSQIRHFKEAGIENILALRGDIPKDGEMSGDF
RYAGELIAFIRERCSLNVIAACYPEGHTESENIAADIRNLKTKVDAGADQLITQLFFDND
YFYRFRERCFLAGIHVPIQAGIMPVVNKKQIERMVSLCGVHLPRKFTAMMERYEHNPEAM
RDAGIAYAADQIIDLTAQGVDGIHLYTMNNPYIAAKIYEAVHRVLAA
>A0A1G0XP96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_45_14|TrEMBL
MANDGLQLEIRFDEGMRNPLRERLENGEFSIFIEVNTPSKNTAFNSSASQFFDFEVAASK
VDNMPVSLAFTDKLQSHDSWNVADFAAAVSKDNRKEHIIYLSGRNTTREELENTLSACKT
YGFTNVVPVSGDGLPGETAKETAKRVFTESLHTQESAITRYDGSFYHGCVTNPFKYTPKD
IYPQYFKLIKKLNLGANFIVTQAGWDMLKLQELRWYLSSRGMHYPSIARIIFLSPENFKL
ISKGKVPGIHISPDFQKMLERELKYSFKQFESAQLRRIQLQAAGCRLLGYSGIQLAGIET
ATQLSVISRRVKEAIEEFDNFDDWKNAYFEYLGRAEMAPYPHRFYMYDKLFSRAHLDFDP
HMTEGKIPPCSSVEKLKYKICDFLFPFAHKQPADESSFTKKLFAGCKGCSYCRLPLTHFV
CPERCPKGIANGPCGNTRSDGNCEFGQGECIHTLRLRLASWLKEIDTLEENYIGHAYRKQ
ANS
>I3IDL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrio sp. BR|TrEMBL
MNDSQPRLSFEFFPPKTPEGKEKLIKVRDQLNEFAPDFFSVTYGAGGSTRDNTKGLITQF
KSDGIAVAPHLSFGGDDETTIKTLIQEYKDAGVDRIVALRGDMPSGVGGAYQLVYANELV
AFIRKHYGEHFHLEVAAYPEIHPQAKSYSDDVGYLKGKFDAGANSAITQYFFNPDSYFYF
VDQCQKAGITQPIYPGIMPIINYKNLTRFSDTCGAEIPRWLRKALENYGDDEASLRAFGI
ELVTDLCDTLLENDAPGLHFYTMNQTEPTAEIVRNLGLIPNDE
>A0A1E4HP98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. SCN 72-86|TrEMBL
MRTGRLAVTAEIAPPRGADLAPVRRAAEHLRGWVDAVNVTDNAGANVRMSSLAGSLALLE
EGVDPVMQMTCRDRNRIALQSDLLAASALGVPNLVLMTGDRPEQGDHPDAAAVFDLDSGA
LMSAARTLRDDGTLLSGRAVDPAPRYLLGAVDSPGPSADRFAQKVDGGAQFVQTQFVFDI
AAFGGWLGQVRDRGLDTRCGVLAGVGPIRSLRALEFMSSIPGVVIPEALERRLRGVPSDK
VAAEGVAACVETLRELRELPGVAGVHVMVVGDERGVPEILEAAGLSRAS
>A0A0S8CTC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium SG8_35_2|TrEMBL
MLVKDIINSKKTCISYEFFPPKLESDWDRLFQTISDLIPLEPAYVSVTYGAGGSTRDRTH
DLLVRIQEETDLTVVSHLTCVGSNRDEIHAILSKYTDHGIENILALRGDLPKGQTHWEQP
ENGFTYAAELVAYIKKHFPHMGIGVAGFPEGHPETPNRLKEIEYLKAKIDAGADYIVTQL
FFDNRDFYDFCERCELAHINVPIIAGIMPITTRKGMIRMAELAAGARIPARLLKAVERAG
SDEYLERVGVHWATEQVRDLIDNNVRGIHLYTLNCSTATLRIYKSLGISSSTQLSM
>A0A0B0DXB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neurospora crassa|TrEMBL
MHIREMLADAERTKAPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIA
ELTCEMVAQAQAYLGLETCMHLTCTDMGEEKVNNALQRAYKAGCTNILALRGDPPREKER
WEAAEGGFQYARDLVAHIRKLYGDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGASF
IVTQMFYDVDNFLRWVKRVRERGITIPIIPGIMPIATYASFIRRANHMNCKIPEEWMAKL
EPVKNDDVAVREIGKTLVAEMCRKIVDAGIRHLHFYTMNLAQATRMVLEELDWLPSPNRP
LKRALPWKQSLGSGRRDEDVRPIFWRNRNKSYITRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNELNRKKWGEPQTVKDIANLFVRYLNQELEYLPWSEAPISSEAELIKDDLIA
LNNRGLITINSQPAVNGVKSTHPVHGWGPANGYVYQKAYLELLVSPELFPEIKRRIEDHP
DITYYAVTKSGNLHTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGLEW
ARCYDADTPSRLLIEEIMDKWYLINIVNNDFHQPRTIFEILNDLSLPDLEKVYTPAHTNG
ATNGVPEASTVPQ
>A0A0J5SVU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus fumigatus Z5|TrEMBL
MHVKDMLTDNESAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEA
WEATEGGLRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
VITQMFYDVDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEAL
EPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQATQAVLEELKLIPSEETP
LQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSIRDITQIFVRYLEGKLDRLPWSDSPISGEANAIKDNLVQ
LNSRGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNP
DLTYHAVAKNRELRTNTRDSPNALTWGIFAGREIVQPTIVDTISFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQDIMDNWYLVNIVNNDFHNTYDLFDLFNGLEVKDLDLEVGPDTAETK
SQPNGAAPEEVAIKN
>A0A0S8CRK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium SG8_35_2|TrEMBL
PRLAKKIAAGAEFIQTQCIYNLDRFEEWMRGVRDRGLHEKVYILAGITPMKSLGMARYMK
NNVPGMDIPDEIISRLAGVPKEKQAEEGIGICLETIARLREINGVSGFHIMAIEWEEKVP
EIVERAGLFPRPKISSE
>A0A241VQ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 5054|TrEMBL
MSSLSQFLKQHQFCISFEYLTTAKPQPVLKTFADFPACMTLADRVQTDHDPAPLDMMSAY
PEDVDKILHYSGKGQDIADFEKFLEMARRKDVHNLLLLSGDKLKQHHDGSENPALRSRYL
ESVNQVVAAKKHGGFYLGVAFNPFKYAEAEHAAQYYKLNKKIQAGADFVITQLGFDLDVL
RDYQQHMKQQYPQIPIMACVMPLTFARARFMHKQKVAGIVLTPYMLNFLEHEKRLNPDMA
EQNVYARCALQILICRHLGYAGVHLSACHQPTEQAKLQQAIAQYAKLSLSECRALWDQLW
QTTSIKGFQPEGVDNYRASGEQILKYKSMHMMHELFFSSKMAKGLGGLVFSSNFWNKPKA
DQALLSTELMTKQGMVGCESCGQCRLGETLYICPETCPKGLANGPCGGTHLDRCEFEDRE
CIHSVKARLAKSVGQVNVLKHEIIPTVAIETRQTSSWKNWFNTKS
>A0A7V9HEA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRVVAAAVPALAALLRHPRFEVLPLDGIEEEVHTHLLAAEAKVTVTASPNKGLEPTLDLA
ERLAGAGYQTVPHLSARLVRDRAHLEDITARLQAAGIRELFVPAGDASQAAGPFAGAAEL
LTAMGSLRDQFAEIGITGYPESHHLIGDEETIQAMFAKAPMATCIISQICFDADVIAAWI
AEVRRRGTDLPIWVGVPGTVDYAKLLRISIKIGLGESTRFLGHHRGWMRRLMTRQFKPDA
LVEGLATRAADVAGLHLYTFNEVARTERWRREALERLGEAGANSSNPSDNQAAR
>A0A4P6PDF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium S94|TrEMBL
METSLTFGQRIFMRPLKERLNDSDTFTVLAELMPGRGYTVEPIRRFLSDYAASGNRSIPP
DFDFAAITLPQNPGGVSNLDPSDILTLLSTTDLPNHPDFIPHISCKDHNQAALNSLLTGY
RQRGVQSVLALTGDKPTSAKGVFDREAVGLLQLISENNRALLLSATPGRLAGLNLLFPGA
AVSPYKYTEASQMQQYFKMEKKAASGARFFITQVGWDWRKARELMLYRKETGLTLPILGN
AYFLTTTNSAPHLMNAGRLPGCFVSDALLARLKTERFEEQVERCARQIAMYRSLGYDGVD
IGGVHEYELFCRLLNRAAEIGDTWSEDCENLCWPPENPFYLYDDQDRRIALSPNKPTRHD
RWFDRAHNHLLDPECKGFRTLKKIMDGSKENGTARKSLFAVERAIKHSLFECTACGDCYL
VENFGYCTMGGCAKGLANAPCGDAKPDGTCGNAEGVICRGEQIYKAAKARSGGLTRLRQT
INRPRNPALQHTSSILNYLFGKDHTMKNAIITIGEDIHASIPKHGAVMRDLHRLGETAYS
ADSPQLEYIRALIESQAADGADYIAVNVDAFGESDPQLAVRIMKEYVRLVRRWGGTVPVC
IDSSDDQVLIAGLKEWYRTDCPVKKPLVNSIKVHTADKLMSLRKEYDFVFIGMLTNEKGS
GAGNDTVEDLVALARQIHTKAMEYGFENDAVIFDTTAFPLAIDMPMMPGTPGYTYRAFET
IKALKALPEMKGVHFSMGISNSCRDLPGRKIGIMRAYVEVAMRYGLDAGIVNARHRFGTR
PADPKLVKLVSAYAAMDGSLEKTNDAIELMGEFCDSLRT
>A0A7W0YUB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MDARTREAAALVELLRRPRFEIIPLDGIEEQVLAHLGTEVKVTVTASPRKGLEATLELSE
RLARAGYPVVPHLSARLVRDHAHLEEIVARLLEAGVRELFVPAGDAPEPGEFAGAVELLH
AMGPLRARFDEIGITGYPETHHLISDEETIQAMFAKAPMATCIISQICFDAGVIAAWIAE
VRRRGIALPVWVGMPGTVDHAKLVRISMKIGLGESARFLRHHSNWMSRLITRQFKPDPLL
RGLAPTLADPATNIAGFHLYTFNEVERTERWRR
>E9JAN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solenopsis invicta|TrEMBL
MRNVILEKHTCETSNADENDSKDNPPTHGFHIKNLHKTIMDLRQSLRDRTRKSKNEIFYS
FEIVSTRKPGTFYRRLLADMEEYSPFFYALTWHNEIASGNDDYLPLDLVENFPPNTLLHL
AAKDSLCKNGDFEHASDLVAFIREQFGDTFCVCVAGYPQKHPESPSKELDLYYLKAKVET
GADFIITQICFESQVLIDFVRDCREIGIRVPILPGLLAPTSHACLEKMMDMCGLDVPVEI
KNDLARMKDDDRAAREYSVDLITRIITDVIESGAACGFHLFTLNRLSLVAEICKRVESLK
>A0A7W0TIC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIDERIASDSEPSFSFEFFPPRTDEGERNLGRALAELSRLRPTFVSVTYGAGGSTTEKR
KTIDIVRHLKRDYGMEAMAHFTCVGAAVGQLREMLDTMRDAGVENVLALRGDPPPGATEW
TATEGGLSFSRELIELIRDEYDFAIGAACFPEVHIHATDAESDLHYLKEKVEAGARFLIT
QLFFDNQAYYDFVARARELGIDVPIVPGIMPITDAGQIKRITDMCGSNIPGRLLRELELR
GDQPGSVTDLGVAYATLQCADLLANGAPGIHFYTLNRSPATRAILSALRLMAPWRGAVPA
>D4X4T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter piechaudii ATCC 43553|TrEMBL
MSDSTTPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGATRQDLRDILQTYKSEGVRRVVALRGDLPSGMGGDAGELRYASE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVGKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVQVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHADAPLAVWKELAL
>R5J0Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:124|TrEMBL
MSVADIYEKRATFSFEVFPPKTDVGMEKLCGKDGVLDKLYTLEPDYISCTYGAGGTNVGK
NLEVLDKIQKDGKCTPVTHFTCIGNTKEDIREKLQTYLDHGIDHMLALRGDLPFGWTGTN
GDLHYATELVKFVRKEFGDKFTIAVAGSPEGHIQCRSLEADIAFLKQKQDNGADFIISQL
CWDMDAFRYWLEAIRNAGIWLPVDVGIMPILDQAATINMALSRNGCVMDRKLCEIISKNW
IFPNPFDKEPFDADVAGKKESFRKAGIEYTINQIDEYRACGVDGIHLYALNKYDDVAYIA
KEAGLIDLV
>A0A241VLR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 5054|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGDHFKIEVAAYPEMHPQADSFDLDIKRFCDKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>J3I2D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. YR681|TrEMBL
MTDPTIPAQADGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPVG
GIGTPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLQAKVDA
GAARAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARAFVTRTGTSVPDWL
AEKFEGLDNDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISHLLGIRAK
SVQKAA
>A0A5L8NQS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter lari|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKITSILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IQKQGKFEIYAACYPEKHNESRNFIEDIHHLKNKVNAGTDKLITQLFYNNEDFYTFKQNC
ALANINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAV
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEEIRA
>A0A2N5RHJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga sp. SG1|TrEMBL
MRKSLESGKCVVLEVLTPRGTNLKKFLDFTEKAWETGIDAFTVTDMPMGRVRMAPWAVSH
LLVESGKEVLMHFTRNTRNMIRIQSDLLGCHALGIENLLLLSGDDPSHGDYPGTTSVNDV
DILDLIRLTKLLNEGTDLAGNRMYGKTNFFVGGALNPFSEKDIERAKQKIEAGVDFLVTQ
PLFQKDVAQNIKEKLNTKILVSIAFFENAKQMNHFSGVPGIEIPEEIIESAEKGDEHVKE
KSFEAVLRFVEETKNLVDGFYIVAVVKDLEKIRMVVEVVKG
>A0A2U8H1R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azoarcus communis|TrEMBL
MNNTELSIEFFPPQTEEGAEKLRAVRARLAELRPSFFSVTYGAGGSTRERTFATVKEIAA
SGSEAAPHLSCIGSTRDSIRAILAEYAEAGIKRIVALRGDLPSGVGDAGEFRYANELVAF
IRAETGQRFRIEIAAYPEWHPQARSPKDDLLAFKRKAEAGADSAITQYFYNIDAYLHFVD
AVRGMGVDIPIIPGIMPIASFSKLARFSDACGTEIPRWMRKKFEAFGDDSESIRAFGLDV
VTAMCEKLIASGAPGLHFYSMNQSALTTEICHRLKLA
>I4VS34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter fulvus Jip2|TrEMBL
MPAVSFEFFPPKTDEQRAQLDRTVAALKAYQPDYVSVTFGAGGSTLSYTGETARHLHEQH
GLPAAPHLSCVGGNRAELAALLDDYRAAGYRRIVALRGDLPSGMATPGDFRYAAELVRFI
REHSGDHFHIEVAAYPETHPQADDALRDLQHFKAKIDAGANGAITQYFFNADAYFRFVDD
VQRLGVNVPIVPGIMPITNYSQLQRFSDMCGAEIPRWITQRMRAHGDDADAVRKLGTEVV
TTLCRRLLDGGAPGLHFYTLNRAKATEAVLKQLA
>A0A2T9YS85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium simulii|TrEMBL
MSKLIAGFLEAQTSGNHFFSLEFFPPKTPQGMLNMRDRLGRIAPWNPLFSSVTWGTSGST
FSQSIEFASMLKVEFGVEPLLHLSCVNMRQGQIDHALRVAQSKGIYNILVLRGDEPTLVN
EIHGEHSSRDGNEKRFSYASELVEYIRNSKEFKSVFTIGVAGHPEGYNNYMDYETELKET
EIPSKEKHGPETDSTSTGDNSARESLSRKEKNELKELEMLSNKVNKGADFILSQVFYSSE
KFIKWYKRCREYGIKVPIIPTLLPIQTYHSFQRIVKLTGVQVPLELSETLARVSNDDQKV
KDVGVIHCIKQIEEIKQATDIIGVHFSTLNLEISLKRILKGAGWGQGLKTETSESEQDCI
ASKSKHNQGGQAGPCDARSWDEFPNGRFGDARSPAFLSDGMYGQVESINNDLEEFGTPRS
DIEMSELFKNFVLGKVGALPWTSDSIGTSSREHTEHLVEMSTKGMWTLASQYAIDGVDSG
DVRDGWGPSGGYVYQRTFVECFVRNEIFEKLRKVLVAHKKEITFYAAKVEQDLQAGPGTL
QNDGMLRLDTSNIEQDMFEDYKQDTESSSKASEKAEETTVLTWGVFPGTAIVQAALVDKL
NFSYWSKEAISIWERWGKLVEQRNKQVGATDKIKEGPPKSAIVGDIKAEGPPKSAIVGDI
KAEGPPKAATVGDIKAEGPPKAATVGDIKAEGPPKAATVGDIKAEGPPKAATVGDIKAEG
PPKAATVGDIKAEVGDIKAEGPPKAATVGDIKAEGPPKAATVGDIKAEGPPKKTGQSTQN
KVMIDSTKDRNEAAKNYHNFLESRHDGGGHWNDPPRQVLNSAASQSKKAQENRVESQSEA
GESMTTVIQQFYGVLSRAEEGGVAAAKVVADTRGRIQTLERVIETLPVYAQNILQQMADE
LRNDNAEGMDVLYSKLVKQDYELGAKWLVGVKRLGGLSIALKKN
>A0A7T2WNK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei|TrEMBL
MVESTAVRLLEDFSLEMTGKDVANLQEAASAIAPGTRINVTYLGNEDLPMRVAAAKAVGE
LGFTPVPHISARRVTSEQALRDFLAALAEVNATERVFVVGGDPATPEGPYPDSLSIIRTG
ILQEYGVREVSVAGYPEGHPDIDTATLWEHLRAKTASLTEQGLGQVVISQFAFDAERVSE
WVAEVRDAGVTGDIRVGTPGPAGVKRLIGYAKRFGVGTSAGIIKKYGFSLANLVGTAGPD
RFITELAADTQVAGDGRGVKTHFYTFGGLSATAEWIRDFSRGA
>A0A667WMP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myripristis murdjan|TrEMBL
MVNQVQRVDGNWQSGKSDSSGASNSGGESSKESSRCSTPVLDADRSDRLRDKMLRRMESG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLETILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAT
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRAETF
LKFVRDCRKIGIMCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIEQAVEMCRLLLESGEVPGLHFYTLNREVATIEVLRQLGMWIEDPRRPLPWAMSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLKMWGEELTSEDSVFEVFTCYITAQPNHSGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSSDPLVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRV
NYHIVNVQGHNLTNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDMPPELVTDGAVS
E
>A0A352IQF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter adhaerens|TrEMBL
MTLVSERQPFNRPDEEAAARFRDLVRSASIEATPRQILTTEHLPDLLPAGTCVYVPFLPK
GQFSDTLEASRRLLDLGMQPVPHVPARMAQSRGQLRDWLAQLDESGVDRLLLIAGDSDAV
AGPFPDTLAVLESGLLAQFRFQGIGVAAHPDGHPMADRATLAQALSVKREYARTTATRLW
VVTQFTFDADVVIDWLQGLGNILEEVPVYIGMAGPTRVKTLIAYAAMCGVGASARMLLRR
PGSARMLGAWKPDDMVRALVQY
>A0A2Z4GHV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcticibacterium luteifluviistationis|TrEMBL
MAKVTEHIDNAKGKTLFSIEIIPPSKGSNSIGDLLSGIEPMMELNPPFIDVTYHREEYLI
KDMPDGGQKEVRTRKRPGTVGICSAIMHKFDVDAVPHVLCGGFNKEDTEDLLFDLSYLGI
DNVMALRGDIAKPFNVFKPKKGGHQYASQLISQIKDINAGKYLYEELESETHPDFCIGGA
AYPEKHYEAQSMDIDFENLKRKVDAGMDYIVTQMFFNNQKYFDFVNKCRANGINIPIIPG
LKVLATKRQLEILPELFFCDMPEDLRKGVAAAKDNAGAREVGVEWCVQQCKELKEYGVPA
LHFYTMSKSNTTLAVAKEVF
>A0A6J4LEG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Frankineae bacterium|TrEMBL
AGADDQGHARPRRAPVLLRVLPGQDRRGRAPALDGDPAARAAAPRLRLRDVRRRRLDPRP
HDRDDRAHRHRDDADAAGPPHGGRPLGRRAAPHRGAARGRRRPQRPGTARRPAGRPAGRV
GQARAGPGVRLRARLARQGVGRLLRGRGGVPGEAPALGRLRQRRRALRREVPRRRRLRDH
ADVLPRRRLPAPARPGRRHRLRGADHPGRHARDERRADRADGGPVRRGLPARARRRAARR
RRRPGRRAARGRRRGDRDVRPAAGRGRAGAALHHPEPVDGDAGDLVAARPAVGAEERV
>A0A1I4ADM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocapsa palsarum|TrEMBL
MSENESCDFPRASRTICPDIRVSFEFFPPKTVAMEATLWESIFRLAPLRPSFVSVTYGAG
GTTRERTHATVARIARETIVKPAAHLTCVAATRDEIDEIVKGYWEAGVRHIVALRGDPQD
GVGAKFRPHPQGYENSAALVAGVRRIADFEVSVSAYPERHPESASVEADVDVLKAKIDAG
ATRAITQFFFENECYLRYLDKVRSKGVDIPIIPGIVPVQSFKQTANFAARAGASVPQWLA
DRFEGLDDDPQTRRLVAATVAAEQVLDLVDRGVRDFHFYTMNRADLVYAICHLLGLRPNP
EQKAA
>A0A5Q4ENQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaeraceae bacterium|TrEMBL
MHINDIFAKHPTTFSFEFFPPKSDEAAEKLFNAISELEPLRPSFVSVTYGAGGGTRTRTH
ELVMRIKRETSLLPVPHLTCVCHTEAEIHDILERYAQAEIPNILALGGDPPKDRPSHIRE
RDSFPYAEDLVRYIRNFKDTYAGRCMSDPRGFGVGVAGFPEGHPGTPNRLKEMDYLKRKV
DAGADYICTQLFFDNRDFYDYRERCELAGIKVPIIAGVMPITSAKGMERMAELALGARYP
APLVRSIERCNGDPAAVRRVGVHWATEQCRDMLDNNVRGIHFYTLNMSTATREIYANLGV
KDSLALA
>A0A449DD38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei|TrEMBL
MSTTLTHADPTLDSTFRDVAQRPPIGLSLTGRPRLRTSASAPENALETDLDNDPQRRLAL
SFEVIPPRSQAQAATLPALLAELDALDPDYLAVTSSAKSGWLHGTADFIRLVTATTHLRP
LAHLACTAGTRAELTTWIHHLLGVGVRGFLAIRGDFPDGATAVPDGHLPHADALVHLLRE
IESANTARLAAGRLGIGVAAYPSGHPESSGPDEDLDVLAAKQRLGADFAITQLFFDPRAY
ADLRRRSELAGITIPLIPGVLPVTDSRRLHTMSRLSGLPVPDDLLRRFDGAADPATARRI
GLEMTAEHIAAILAGGADGLHIYTFNDRATTLDLLEMLDRLGIRLDSAPAPVPASAPQPS
>A0A2T9YB56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium simulii|TrEMBL
MKVIDKINSALNDERPFWSFEYFPPKTQEGVLNLYERIERMTKLNPTFIDITWRWGGKSK
DLTQDICINSQTVYGIESNMHLTCTGSSIPEVHNVLQTAKKNNLQNILALRGDLPNPPKG
SIVSPSATFADPIDSSDYEADLSSLKNLVSAEQLVKYIRANFSDYFCISVAGYPEGCTRN
EDIDKDIIVLKKKIDAGADFVVSQLFYDTSKYMLWYNKCLENGITVPILPGIMPIQSYSG
FERMVKLCNISVPDEIWSSLSSIKNNDLAVKDFGIDYTVNMIKKLMTFGIKGFHFYTLNL
ERSSRLILEKLFFVSVPPKSSLNDTQGFNNITSSTNKSLPWPSACQEKRAGENVRPIFWH
NNADSYILRTESWDEFPNGRWGDYRSPAFGELDYGKYWSFTLEKILDLWGAPESENDIQN
IFYNYCSGRLESLPWSVSSIQTESNEIADNLSILNKSGYLTINSQPNCNGADSSDPVHGW
GPKNGFVYKKAYVEFFIHPARFIKLLKKIDEFNAKNGSLDINSNIITYLATSLNTDKLYS
NFDTNKPNAVSWGVFPGCEIIQPTIVDSNSFLAWKDEAYDYWKMWASSYSSEYAKSADFL
LNIKDTYFLMNIVDNNYTRSPDFIYNFLLEI
>A0A1G9DT03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. YR527|TrEMBL
MSRRSDAAVVRRLLLAARYEVLPTARIEEVVTTSLPVGRTVTVTASPAKGLEATVDLSIR
LAEHGYDVVPHLAARMVSSRAELAEITARLKAAGIGKIFVPAGDAERPGEFPGALELLEA
LVDLGDPFGHVGVAGYPEDHPTIIHDRLVQAMWDKRHHATEIVSNLTFDPAALTDWVRRV
RARGVTTPILVGLPGPVERAKLLTMATKIGVGESTRFLAKNTGMFARIAAPGGFSPERFL
TRAAPDLDGPEAVVSGLHLFTFNQVVETEAWRRDLLTRLGGDPQ
>A0A1S1QUY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia soli|TrEMBL
MTAAGSTTRMSTPTVAECLASGRTSFSFEFFPPRTAEGERHLWTALREIEALHPTFVSVT
YGAGGSTRDGTIRVTERIATETTLTPIGHLTAVNHSVGELRQVIGGYAGAGVRNVLALRG
DPPGDPQAEWVRHPDGLGHADELVRLVRSLGDFCVGVAAFPDKHPRSPDLETDARFLVRK
LDAGADFAITQFFFGADDYFRLVERVRRLGCDAPIIPGVMPVTNVAQIERMAQLSGADFP
ADLAARLYEVADDPAAVRAIGVEVATELSERLLAGGAPGLHFITLNRSSATREIYQSLGR
>A0A087D8X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium scardovii|TrEMBL
MHSPMFSLEVFPPKRNAPVGTIYDTLDGLEGLSPDFISVTYGHGTHSDRTATARIANTIR
KEYRIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDPIEGLEPSRDFAHASDLV
AYIREHKPDMKVFAACYPEGHIQSASLDEDIAHLKTKVDAGATHLISQLFYDNEDFYRFL
DKARAAGIDVPIEAGIMPVAGAKSTRSMAERNRTRIPRAVESMLERWGDDVPTLRAAGIN
YACEQITDLVANGVDGVHLYTMNRPASTRRIWRNVEALFAVGE
>D1CBD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermobaculum terrenum (strain ATCC BAA-798 / YNP1)|TrEMBL
MKDPFVERLEKGPILSDGAIGTQLYERGVPYGKSFDELNIVDPSLVSGVHIDYLRAGAEI
ITTNTFGANRIRLKEFGLEKKVRDINLRGVKIAREAREIVGVPAFIAGSVGPIGRPATEY
NSLTDRVIGDTFREQIEALLEGGADVIMFETFSELEELLIAIEVAKEVCELPIIAQMSFG
EDELTHGGDTPEDFVRALKDSDVDVIGVNCSVGPQGTLDVVMRLIAAGAHRVSAQPNAGL
PSRRGQHFVYISTPEYFAEYAKKFVSAGAVIVGGCCGTTPAHISAMAAAIKDGNRATTVT
VNIEQKSPHITAIPSGEPEPTKLAQAIKRGEFIVSVEVDPPKGLSARKTLEGAKMLAEKG
VKWINIGDSPMARVRMSCIALAKLIQETTPIEAIIHFTTRDRNVMAIQSDLIGAHAMGIR
NVIALTGDPPSLGDYPDATGVWDIDSVGLIKALSRMNEGFDLAGKQIGAKAGFCIAAAVD
PTAKDIEFQIDRMWQKIEAGAHLIMSQPLYDVEDLQKFLDRVGNIPVPFILGVLPLQSYK
HAEFMHNEVPGIYVPEHILDAMRRAGSNGLQEGVRLAQELVHQAQHLVQGIYLMPSFGRY
DVCAQVFEALDIDKRPTASNSSEAQAANK
>A0A7V5NXW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hellea balneolensis|TrEMBL
MIIEETKGRPSIPVSAPGRLGRAGGGDVHISFEFFPPKTEKAKQDLWQAIKKLAPLAPDF
VSVTYGAGGTTRRRTHETVTRIARETDLSPAAHLTCVGATREEISDIAKAYWQDGVRHIV
ALRGDPPGGLSAPYVPTEGGYAYASDLVAGLKKVADFEISVAAYPELHPESLNWDDELDN
LKRKIDAGASRAITQFFFSAETYLRFRDRVRAAGIDIPIVPGIMLQPNYAGLKRIASLCY
ISIPDWYHELFESLDDDPITRQMLCATTAAELVAALRDEGVRHFHFYTLNRADLAFTTCR
ILGVKA
>A0A7Y9BM18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. BR123|TrEMBL
MALGTASTRTDRARTVRDLLASGDPSYSFEFWAPKTEKGERNLWDALRRIEAVSPSFVSV
TYGAGGSTRGGTVKATQQIAADTTLTPVAHLTAVDHSVAELRNVIGQFADAGIRNMLAVR
GDPPGNPMGPWVPHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSEDRDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVEKAGCDTPIIPEVMPVVAIKQLDRLPQLSNAVF
PEAVKERMLAVKDDPAAVRSMGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQRA
>A0A844RU49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium yuanmingense|TrEMBL
MSGAMTDLTTPATADRQDGHLKRAAISFEFFPPKTEEMERNLWETVNRLAPLEPKFVSVT
YGAGGSTRERTHSTITRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRG
DPVGGIGTPYSSHPEGYQSSAELVAGIKKRHGDIEISVSAYPEKHPEARDFDADIDTLKA
KVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPVVPGIMPMHNFKQARNFVTRAGTTV
PDWFAAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLG
IRAKSAQKAA
>A0A7Z8MA06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. 007/AIA-02/001|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A321LRM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium AA13|TrEMBL
MRDFKEAVTDDRVYVFDGAMGTMLYSRGVYINRCYDELNLTGGDIVFSVQRDYVKAGADI
IETNTYGANRLKLSGYGLDDKLFEINNTGARIAREAAGDRAWVGGAMGPLGVRIEPYGPT
SAEEAQALFREQAEGLLEGGVDLFVLETFSDITEIKQAIIAIQSICDLPILAQMTIQTDG
STTYGTSPEAFTTELDEAGADVIGLNCSVGPHTMLEAIEKMHGVTKRKLSAQPNGGLPRQ
VDGRLFYMASPEYMAKYAKRLIQAGAKFVGGCCGTTPETIKQIASAVAALSPGRSTVPVF
VPDEKTLDVKVTPREKKSEFARKICANQFVTSVEIVPPKGCDPTKMLEQVKLLKEAGVDA
VNVPDGPRAQSRMGVLAVSTLIEQKVGIECVTHYCCRDRNLLGMTSDLLGAAGLGLKNLL
IITGDPPKMGPYPDATAVFDIDSIGLTNMVNRLNHGLDIGGNPIGKPTSFYIGVGVNPCA
VDLEYELRRFEWKVEAGAEYAITQPTFDTEQLRRFLKRIERFRIPVIAGIWPLVSYRNAE
FLANEVPGVVVPESVLERMQRVTDKDAAREEGLAIARETLLEIRDLVQGVQVSAPFGRVQ
YALDVFSIL
>A0A414WFV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM18-10|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A0R3CHR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium yuanmingense|TrEMBL
MTDLTTPATADRQDRHLKRAAISFEFFPPKTEEMERNLWETINRLAPLEPKFVSVTYGAG
GSTRERTHSTIMRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPVG
GIGTPYSSHPEGYQSSAELVAGIKRQHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A2U2MV43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium catulorum|TrEMBL
MHTPQFSLEVFPPKRNAPVGTIYDTLDGLEGVNPDFISVTYGHGTHSDRTATARIANTVR
SEYGIPTVAHLTALYSDEEVVDQALDMFDAAGVFGVLALRGDVIEGQREAGAFRHASDLV
SYIRDRRPNLKIFGACYPEGHIECPSLDEDIHNLKIKVDAGATNLISQLFYDNDDFLRFV
DKARAAGITVPIEAGIMPVTSAKSVRNMAKKNATVIPRRLDAMLEKWGSDRESLRRAGII
YASQQINDLVAQGVDGVHLYTMNHPGTTRRIWSNVKPLFQED
>A0A3C7VYU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halieaceae bacterium|TrEMBL
MARQPEISFEFFPPKTDAGREKLLAQTAPALAALGPGFFSVTYGAGGSTRDRTFDTVTAL
ADQGLTVAPHLSFGGDDEATIGDLLERYKARGIDRIVALRGDIPSGNGAGATIVYANELV
AFIRERTGDHFHIEVAAYPEIHPQALSYESDIRYLKGKFDAGANGGITQYFYSPEAYFYF
LDQCAAIGIEAPIVPGIMPITNFQNLARFSRNCGAEIPRWICQRIEGFGDDQESIRQFGI
EVVTQLCGTLLDSGAPGLHFYTMNQVEPTRQICENLGLRG
>A0A0S8DZ15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium SM23_29|TrEMBL
MSLKDKIKSDKFIVTSEIGPPKGIDVKEILEDAELIKGRVDGINVTDLQSSVMRLGSLAM
CRLLKERGHQPVFQITCRDRNRLALQSDVLSAAVLGIENILALTGDHPSSGDHPQTKPVF
DLDSVQLLEVIRTLQQGIDMAGKPLKGIPKFCVGAVVNPGAEPLEPELMKLEKKIKAGAE
FFQTQAVYDVEKFKDFMERIKHLNVVIIAGIVLLKSAGMA
>D6KG64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. e14|TrEMBL
MSTARTAVGALLLEDFSLEMTGKDVAKLEEARETIPQGTRINITFLGNEDLRMRLEASRA
VKRLGFVPVPHLSARRLGSRAEFAEFLAALRAEGACDNVFAVGGDPARPKGPYEDSLALI
ESGLLQEHGVRHVGISGYPEGHPDIAADVLRTALRDKSAALRARRLDGGVITQFCFDVDP
VLAWLAQLREQGITLPVRIGVPGPAGVRRLMSYAARFGVGTSASIAKKYGLSITNLMGTA
GPDRFLHALAEGYDPARHGDIKIHFYTFGGLRATSEWIARFRKEHHV
>A0A356SGR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halieaceae bacterium|TrEMBL
MNAAKKLLNSLYFEVIPMKGFEEKLDVLKAGDRVGITCSPKQGLQVTLDTVSKLSGRGFS
LTPHIAARQVKSQQHLRDIVAQLTDSGITSIFVPGGDLDQPMGDYNSSAAVLNDLSEMDH
PFTRIGVASYPEGHPAIPDDILFDALAAKQGIATHMVTQMCFDMPVLLKWLSNMRDRDIK
TPVWIGLPGVMDRMRLFKTSLRIGVGQSAKYARKQKGLAGMLLRSATYKPDSLFKELKPA
MDDERMAIEGLYMFTFNQIDNTVQWSQEQLKRLG
>U6R9Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. HPS0048|TrEMBL
MKVIDLIHSNEKTAFSFEILPPLKGTGIEKLCRDIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNKLRRRPGTVAVAAAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYYHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDSDIYWLKKKVEAGAEYAVTQLFYDNQKYFDFVEKARQEGINIPIIPGIKP
FKKASQLSMIPKTFKVDLPDDLVKEALKCKNEAEVQQVGVEWCVKQCRELMAHGVSSIHF
YSIGAVDSIKEVAKEIY
>A0A176F0K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp. HI0049|TrEMBL
MTGMPDDLSISFELFPPKTEAGVTRLRDTVMQLSAAEPKYFSVTYGAGGTTRDRTARMVE
MVANRTGLPVAHHFTCVGASRAEIDRQAEAFWENGIRKIVALRGDLPEGETVPEDGYHDA
AELVGALRRVGDFDISVAAYPEVHPEAKDAKADLDHLKRKIDNGAARAITQYAFDTDTVL
RFIDRARAAGIEAPIVPGIMPVSNFAGLKRFSEGCGASVPDWLCQMFDGLDDAPDTRAMV
ATGVAAEQCRRLIDEGVREFHFYTLNQPKVTLAVCRTLGLTPDILAENAA
>A0A2V8IQ62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MALPDFRTELDTRVLVCDGAMGTMLYGRGVFLNRSFDELNLTQPDLVAEVHQAYARAGAD
VIETNTFGANRVKLGAFGLADRVHAINVQGTRIARHAARDSVYVAGAIGPLGIRVEPWGK
TGVDEAEEYFREQARALVEGGVDLFVLETFRDVNEIGAAIRAVRSVCALPIVAQMTTEED
GNSLDGVAPETFVPQLEAAGADVVGLNCSVGPAAMLETIERMSHVAHVKLSAQPNAGRPR
EIEGRNLYLCSPEYMASYARRFINSGVRLVGGCCGTTPDHIRHIKMAVRALAPAAIRQKR
DPASGVTRKPAVTPVLRAQKSRMAHTLARGGFPISVELLPPRGYQAAALIEQARQLKIRG
IDLVNVPDGPRASARMSALAAALLVQQQAGVETILHYACRDRNLLAMQSDLLGAHSMGVR
NVLLVTGDPPRIGDYPDATAVQDVDSIGLTNVVAQLNRGLDIGGQPIGEPTAFHIGVAVN
PGAFNLDEELRRFAYKVQAGAEFAMTQPVFDLAEFEAFIVRVRTHDVPIIAGILPLESTR
HAEYMANEVPGVRVPDAVIERMRRAETNGRAAEEGLTIAREIAGQIRPLVQGVQISATPK
AIDVALGVIDALGA
>A0A7C5WHS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MDIPFRERLARGDCLLFDGGMGTEIYAQGVFLNKCYEELNLERPAVVEAVHRRFLQAGAQ
AGETNTFAACRPRLEPHGLGDRVAEINAAAARLARAAVGHRAYVAGAVGPLGIRLEPWGP
TTVDEAVELFKEQISGLLDGGIDLVVFETFTDLVEIQAAVRAAREICELPVVAMMTVDEE
GRTPEGVPPEWMVQKLEATEAEVIGINCSVGPASMLPVLETLAASASLPLAAMPNAGIPR
PVEGRMIYLTSPAYMGRYARRFRRLGARVIGGCCGVTPEHIQAMSEALGQDPSGEVVPKV
VVRAPQIVARQPVPQREKSRLARQIADGRFVTLVEMAPPHGWQAEPVLRLLAPWLDAGID
AVVVPDDPRVSVRLSPMAMARLVLEEIEARGASAEPVLQYTCRDRNLLGMQSDLLGTHAL
GLRNLFLVTGNAPRPGDMSWSSTVFDVDAIGLTNMVYRLNHGLDVGDTPIGSPTAFFPAV
LATIGLVAREEEVRRFEWKVDAGAEFALTSPVFDPEELASFLEAVDSVRVPIIAGLWILT
SLRDAEYLAAEVPGVTVPDTVLDRMAAAAAKGEEASEGLAIAREVLEQVREQVEGVFVCG
QGALQPGSLEILRDVVGTSRAVERVFPGRPGIKGGAEGQRYGD
>A0A2V9B4B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIHDFNERLKDSILIADGAMGSMLHEAVGPQRCFDELNSTEPEAVFRVHQAYIEAGAQI
IETNTFGANRFKLAPHGLADETTRFNSRGVKIAREARESAAREVLIAGSIGPLGLGVQSR
HPSPDEILDIFHEQAQALEERGVDLYCLETFSNLDELLLAIDAVRSFSGLPIIAQLTYSE
EGITHGDVRPRDAAARLKDKNVQVIGANCTLGPQALLPILQEIAAVDGVRVSAMPNAGFP
KREGDRIVYPKSSPEYFALFAREAVALGVRILGGCCGTTPAHIQAMAEAVRSLRPAKRAA
ASASVEVVIAETPAAARTAQREPESKLWKKLRAGEFVISVEIDPPKGVSLDRVFEQVDRI
MACGRVDAIDINSGTMARVGMDALMTAAALEARGVETIPHLTTRDFNIIGLQAVLLGAWT
VGGVRNVLAITGDPPSVGDYPETSGVYEVDAVGLVSVLSRLNQGRDWSGKTLGGSTNFTI
GVALNPVAEDLDHEIERFQAKIEAGAHFAMTQPIFDPAHWHAFLKRLGRKPPIPILVGLW
PLNSYKQALRLNNEVPGIVIPQSVLKSLETAGADARACGFQMAREMLAWSRSELAGAYLI
APFKRYEEILEVL
>F5ZFS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas naphthalenivorans|TrEMBL
MVSYAQGVDALNQSLSELRDIDVSFEFFPPKSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELRQIAQDYWDSGIRRIVALRGDLP
PGVKDTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIS
QFFFDTSVFLRFRDRAAAAGIDLDLVPGILPVTNYQTLVKFAGFTNVHVPGFLHKMFDGL
DDDDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRAG
>A0A2V7UVH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MGETKAHAPGVKPFLDRLREGVVVCDGAMGTMLYARGIFVNRCFDELNLSNPGLVQGIHQ
EYVDAGADVLETNTFGAHRFKLGPHGFEGQVVKINREGARIARAAAQGRALVAGSIGPLG
KPLEPFGNVTFDEAVDTYREQAEGLAEGGVDLFLVETMPSLDQARAAVTAVRAVAELPIV
VSLTFNEEGTTFYGDQPGEVVRAVEGWDVAAVGANCSQGPQPMLETVKRMAAAATRVKLS
AMPNAGAPALVDGRYVYLCTPEYMASYARRFIAAGVSFVGGCCGTTPAHIRNLVRSVRML
QPAREVVTVEAPARPKEAPAPVPREDKSPLARKMGKKFVVSVELDPPKGADPGRIVDRAQ
YCRENEVDAINVADGPRASARMSAQSLCVLLQNKVGVDTILHYTCRDRNLLGIQSDLLGA
YALGLRNILAITGDPPKLGDYPDATAVYDVDSIGLIRIMDHLNHGCDLAGNLIGPALGIH
IGCGADPSKPDQEKEIRRLEEKVRAGAEYVMTQPVYDPRTVEQFLDEVQHLQVPILIGIL
PLYSHKNAEFLHNEVPGMVIPDDIRERMRKAGSGEVAQAEGVAIAQEALLAARQRAQGTY
IMPPFNKVELAVRVIEALG
>A0A7W0Z6Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MSRTIAERLRSADPSFSFEFFPPKDAAAERQLWQALRELERLRPSFVSVTYGAGGSTREG
TVRVTERIATDTTMLPMAHLTAVNHSQRELRHVLGRFAAAGVRNILTIRGDPPGNPEAEW
VRHPEGLAYAEDLVRLTKASGDFCVGVAAFPYKHPRSPDLAADAHYLVRKIRAGADFAIT
QMFFVVEDYLRLRERVSALGCGVPMIPGIMPVTTIGTIERSAQLSGAAFPDRLRSRFEAV
ADDPAAVRAIGIEQASELCQRLLDEGAPGIHFITMNRSTATREIWFNVQARVSV
>A0A0J1LGF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. MGH106|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGGGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A2V9RY37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MITGPMKAGSRLERVLRSGRFAVTAELNPPDSADPQAVYERALVLASVCDAINATDASGA
HVHMSSVGVCALLTRAGYEPVLQVSCRDRNRIAIQGDLLGAAAMGVQNVLCLTGDGVQAG
DQPEARPVFDLDSITLLRTARILRDKGQFLSGRKLESPPRLFLGAAENPFVPPFDFRPLR
LAKKVEAGADFIQTQFCFDVSRLRQFMAKVRDLGLHEQVFILVGVGPLRSAGAAEWMRSK
IPGVAIPEEVIVRLKGVPEDRQKEEGRRLCLEVIREIREIQGVSGIHVMAYRQEELVAEI
IEEAGLLPRRVQPVEAAKE
>A0A1W9IRF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. ST-bin4|TrEMBL
MSREPRRLKDVLDQGRFAVTIEYNPPKGTNIAGILDNAKELIGLVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNVLCLTGDYPTVGDHKE
AKPVYDLDSVQVMKLVQGLNEGRDMAGHKLDGPTAFTIAAAATPEADLVGPVLAKFEVKV
KAGAQFFQTQAVYQPDVFASFMKAVRPFKVKVLAGILLLRNAKMAEFMNANIPGMSVPQE
MIDELRAAGDKSEDAGVEIAVRAIKAVRRHCDGVHIMAIKGIHRLREIITKAELG
>A0A2T0Y847|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Isoptericola sp. CG 20/1183|TrEMBL
MVAEASLTPRHRPTVSFELMPPRRPEAAPKFWETARRLVAADPDFVSVTYGAGGGDRATA
RQVVATLLEGTPVLPIAHLTCVGASREDVSDVVDEFLEAGVRSFLALRGDPPRDQPDWRP
PADGVHSSIELVALLREVEARRCAADPAAAVRGAARPLTVAVATFPDGNRQAGTTRAQEV
QRLLEKQQAGASFAITQLFYAADSYTDFVAEARAAGVTIPILAGLMPTTEPRRLRRVEEL
TGVPAPRHLLAALDALPDPEAQHAYGTAYSVELAQRVLDAGAPGLHVYTFNKYRPALDLL
EGVHLGGRTPHGVPDLARRPLVPGIPTEAPAV
>A0A3N5JJZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MQPRISFEFFPPRTEEQKLILESTWQKLAPLRPDYLSVTFGAGGSTLDATRETVEALAAG
TDVPVAPHISCMARSEPMLREILQAYRDKGIGRLVVLRGDRPEGLSGPGPFQHADELVAW
VRREFGDGFHIDVACYPEFHPESPSPQSELRYFRQKVAAGADAAVTQYFYNPDCYFHFVD
DCRRIGIEVPITPGIMPITNYRQLSRFSEMCGAEIPRWIRHRLEGFGEDGAAIRAFGLDV
VTDLCERLLAGGAPGLHIYTLNRANASLLLWQRLNRSVGAGYSSPKMAT
>A0A523FBM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRDNNGDLEAVRRLFLKPEFEMLPFRSAIDQIEFLPEAATVTITASPAKGIEPTLDYATK
LAERGFDVIPHISARSIADETHLSRILDAIAEAEIDRIFVIGGDSKDAGEFPDGLSLIQA
IESLGYPLPEIGVAAYPDGHPFISRETLRQALKDKQPYASYMTTQICFDPVVISDWIADV
RSDGITLPIHLGMPGVVPVHKLISIAAQIGVGDSVRFLSRHRGLLGRLTRQSTYSPDRLA
MGLSQAIADPTADIEVVHFYTFNQVESSEAWRRDWLASIDG
>A0A0B4DQH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hominis|TrEMBL
MAAARAGGEASPQVPFSFEIYPPRTLAQLPALHETIRVLAEAGPRFISVTFGAGGSTTDR
SLAVLTHILRETRVPPVAHVTCVGSSYAEATTVIRHFLDAGITRFLAVRGDPPLGLGEDD
IVFGDLESAAQLVQLIGRVHAELSTYREREMPGVPGAVRVIDGERVDIAVAAFPNGHPRS
RHRYEDIDALLAKQAAGATSAITQLFFHADEYLDFVARARAAGVVIPIVPGIMPITSPGR
LRRVLELTGDARPDSLAAALESAPDAAAQREVGLAHAAALARAVVAGGAEGVHLYAFNNH
ETVLGVLRTAGLIPERRS
>A0A3S4XVV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus equuli|TrEMBL
MSYAKEIDHLNQSVADLNGQINVSFEFFPPKNEK
>A0A2V8TRS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MVHGDHPDAKPVFDLDSLQLLVLANLLRGGRYMSGREIVPAPDLFPGATENPFAPPYDFR
PLRLMKKIEAGARFIQTQITFNVARFAAFMEGVRDLGLDRRVPILAGVAPLRSARAARYL
QERVPGMEVPDAIVRRMEQAGPDRTRREDEGIRICVEIIDQLRDIKGLAWFHLMPIRWEE
AVGEIASRARLLPARASLLGPFAAAAVDDGGAEGRAAADGSALQRAREHRA
>A0A2E4FK94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTSTPNARFNQAPAPAGVAXSSIHLIRDIYAERQAEGHPALSFEFFPPKTPKGDVALFER
TLPALQTLRPDFYSVTYGAGGSTRDKTLAIVDRIQREHGATTMAHLTCISTSRSEIERYL
FEARTKGIKNILALRGDPPLETGSERFDRGFEYSYQXVEFIXQMGDFSIGTAGFPESHIA
CTEGRHVDWQRLKAKIDRGADFVLTQLFFDNDDYFAFRDYLVDTLGVSVPITPGILPILN
XGQIKRXTALCGATLPAALATKLESYGDDADAVANFGIELATRQCEALLAGGAPGLHFYS
LNKPHAATEIVRNLGLRD
>A0A2G6HT73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKILDQLSPNSKPSFSFEIIPPRRGKSAQEILDIVEKLKPYNPSFIDVTNHSSEAVYEES
EDGTIRRRVRKKRPGTISICGIIQNRFNIDTVAHLLCQGFTREETEDALIELNYLGIQNV
LAIQGDEQNFKRTVERHRTVNHYAKDLVKQIVDLRTGKYIEELEGADPIDMCIGVAGFPE
KHFEAPNMKTSMRYLKQKVAAGADYIVCQMFFDNAVFYDFKKQCRDEGIQVPIIPGIKII
DRVKQLHTIPKTFHINIPDKLVDGIMENRKSVKKIGLDWCLKQCRDLLHHGENHIHFYIM
NDVSRVIKVMDALFSSKKAEKPNNLQL
>A0A1C5N9Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Blautia sp|TrEMBL
MLGIENILCLTGDHTKMGDHPQAKPVFDLDSVSLLHTVQLLESGVDLGGNQLVGEPPKFS
KGAVVSPCSDSVDAQLAKMERKVAAGADYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGII
IPKSAGMAKFMNNNVAGIHVPDEMIEELKADKEKTKAGITGVEIAARIIKECKPYCQGVH
IMALGWESKIPALLEQAEI
>A0A0M3TU02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thioglobus autotrophicus|TrEMBL
MQLSFEFFPPRTDQGKLNLKQVRQELSAIKPHYFSTTFGAGGTTQEATLETVLDIQANDG
VSAAPHLSCIDSEKSKILALLSQYKAAGINRIVALRGDIPSGVRDIGDFHYASELVAFIR
HEFNDHFHIEVAAYPEMHPQAKNMNTDIQHFANKMKAGANSAITQYFYNVDAYLRFVDDV
QKLGIDAPITPGIMPITNHDQLLRFSNMCGAEIPRWVEKRLAVFGDDLESLSAFGLEVVD
NLCDQLKSQGVENFHFYTMNRSQPSLTLAKNLL
>A0A4V1TF52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacteraceae bacterium|TrEMBL
CIGRNRDELRAMLAEYQAHGIRRVVALRGDLPSGYGMLDASSGEFAYASQLIEFIRAETG
DWFHIETAAYPEVHPQARSAQEDLRHFAGKIQAGADAAITQYFYNADAYFRFVDDARKLG
VDVPVVAGIMPITNYTQLIRFSDMCGAEIPRWIRLKLAGYADDTASLKAFGLDVVTQLCE
RLLAGGAPGLHFYTLNQAGPTSAIWKRLGLGD
>A3CL12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis (strain SK36)|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANELQIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A5R2BWZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira levettii|TrEMBL
MIQILLEVVPRDLSVVIQEVDFVKNKFKQITGINIPDLLRFENRSWDVASVVRPVFPNVI
PHIRAIDFDLDNCEPLVKTLQELQIASVVVIKGDPPTDMSKQVYPTTSVKLIKKLKKEIQ
HLKVYAAIDQYRVGIKDEFDYIEMKKDAGADGFLTQPFFDMRLVDIFSEKLRGTEVYIGV
SPVVTEKSQSYWESRNRAYFPKEFRPSLEWNVKFAKDVLTYCSEKGMNAYLMPIRINLEE
YLHQIFD
>A0A6M0IS56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma agri|TrEMBL
MTKISDHLKAANGKPIFSIEVIPPIKGDTLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PMPDGTIQKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFSREETEDFLIDLHYLGID
NALVLRGDPAKPFSTFKAKENGYTYASELVEQVANMNRGIYLHEEDTPLAPSNFCIGVAA
YPEKHFEAADHDTDFHYLKQKIDKGADYIVTQMFFDNQKYIDFVERCRQAGITVPIIPGL
KPISTRKQLQVLPRIFHLHLPDDLVKAVESCENDQQARQVGVEWSIQQCRELAAYGVPAL
HFYTMGKSDNIVKIARELF
>A0A8J5XH89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diacronema lutheri|TrEMBL
MSEFTTVLIMPDVVRRGLVSDVVGRFERRGFAVIGLKMLNVTRSVAESRYAGQPDAATRA
AALVEGPCVCVVVYGASAVSTALAMAGDSLAPLTCAPGTIRGDLGSGSSSCVVEPAADAD
GARADATRWFGASELTEPVLHKSIKLVDKIAHWVSENGTRPFISFEYFPPKTADGVAKLR
QTLALMAQQRPLFLDFTWGAGGSTSELTIELCADAYAAHDIEVNMHLTCTNQAPALCGEA
LAEAKRKGIRNIVALRGDPPKGQEKWEAVAGGFSCALDLVKYTRQQFGDWFGIQVSGYPE
GHPDVIKPVAELGRPLSASEQKRLVTVGSGASAEQFVCSDADFDRELGYLKQKCDAGADC
VITQMFFDFEVFEAFVTQARAKGISAPILPGIMLITAYGGFTRMTGFCKSRVPAELVAKA
EALKEDAEGFKEMGLSWTVALCKQLVASQLVPGLHFYTLNQSANTQQILQRLGLLLEQPT
EALDEGDTLKGTHIA
>F9CZ31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosarchaeum koreense MY1|TrEMBL
MAIIYEINPPKIPDGEISDDEINSLVEKLLQRVSDISNFCDGIHVTDSVLGTKRVSALSI
GRLLKSIHPNLQITISMRVRDKDMNLIKHLTKESIELKLDGILILKGDPSKENPTDSGLI
PSQVVKELNELGYGNKIDFFLSLPSNPNFEKIQKKIVAKPKGFMTQVIHSTEQVQRISNE
LRPKGLRIIPCVLLPSDKNNNSAKFLELDWSNYKENPSNFIKQIHNISGDVLVTSPNDFT
FAKETLMKI
>A0A7R9CBP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Timema cristinae|TrEMBL
MFVDNGSKYKGGFAHAVDLVKFIRREFGDYFTICVAGYPLGHPEATSYQQDLIHLKEKVD
AGANFIISQIVFNAVCFSQFVKDCRNIDIAVPILPGVMPVQSYKSLERTSSICHIPIPRA
ILDAVKPIEDNDDAVRNYGIHQAVQMIKEMFSLGCATGVHFFTLNR
>A0A2S9B2H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MYb60|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYASDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEHDLQNFVHKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A1C7C8L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius|TrEMBL
MLLSQQKSKKKKVKYMTSQTPSLSFEVFPPNPAVGNEKILLALEDMKGLSPHFISVTASN
NKYNIKETTVPLANHIQNDLAIPTIAHLPAIYLTKEKVADTLRELDAVGVHRILALRGDI
IPGVEPLKDFTYATDLIEFIKEKAPQFDIVGACYPEGHPDSPNQISDIQNLKKKVDSGCS
SLVTQLFFDNERFYDFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRA
ILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNAATARHIYNATHALFKSH
SNSEK
>A0A3B1DVF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MRMIIKNFNQKYNHKSYNLKNKIKISFEVFPPSNSFLEDSLLNSVRILNQCRPDFFSVTS
STRVDSRNKTFLIIQKIRVLTNAIVFAHFTSAGLTTYEINDLASQYWNNGIKNIIALRGD
LPDQCSQKVIYASDLIKLLNLINNFEIWVAAYPEIHPESRNLQEDLINLKKKSDLGVKNA
ITQFFFSVEKFIKFREKCLNFGLDINLIPGILPILNMEQLKKFSNMTRVDVPKWIFSSFE
KFSNNEKQRINLSVNIAVNLIMRLYHEGIRHFHLYTLNQSYLSLQICQKLGLI
>A0A1V5PP04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium ADurb.Bin360|TrEMBL
MQVVLIGLGRMGANMARRWARGGVNVVAFDQSEEARAAFIEQITALAAADVDVISLETFT
DLYEIREAVAAARQVCDLPVIASMTFTRDDRTLLGDGPEKVARALVEMGADVIGVNCSGG
PAQLQRILQRMKLAAPEVRLSAGPNAGWPEQVAGRIMYPATADYFAEYALAFRQIGAALI
GGCCGTTPEHIAAMRRALDAPPGPEVELAVMRHLEPEPAENGATPPTRLAEKFAAGKFVV
AVEMDPPHTISSHKLLAGASLLADVGVDVINVADSPMARMRMSPWAVCHLIQKEVGMETV
LHFPTRGRNLLRVQGDLLAAHTLGIRNVFVVMGDPTAIGDYPEAMDNYDLAPSGLIQLIK
EKLNAGRDHAGSDIGRPTAFFVGGALNLDPPEPEREIKVLRRKLRSGVDFLITQPVYQPE
RAQAFLERYTAEYGPLPAPVLAGILPLNNLRHARFLHNEVPGITICPEIFERLERADKES
AREGVRIAAELIEQVRPWASGVYIMPAFSRYDLAAEVAEAALRL
>A0A8E0IEK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei subsp. paracasei CNCM I-4270|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A3B8HEP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacteraceae bacterium|TrEMBL
DRNRIALQSDILGAASFGINNILCLTGDHQQFGDHPNCANVFDLDSTQLVRTATMMRDEG
KLLSGFEMKSRPEMFIGAAENPFADPFEIRVMRLAKKVAAGAQFIQTQCIYNMPKFKLWM
QGVVDKGLHEKVCIMAGITPMKGLGMAKYMKNRVPGMDVPDDLIARLAGIPKEKQAEEGI
KIAIEQIEELKQVTGVRGFHIMAIEW
>R8E0A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VD133|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLHKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPNFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1Q7GBQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_40CM_56_16|TrEMBL
MARNPLRECLQSRRFCHVVEIVASRISREARLLEVASQLATTPGVVAGSITSYAGGAPGQ
DPVRVGTAARARGLTPNIHVTCVSKDRQELRHYLETIAGLGLENVFALTGDYPKDANAVF
DLDSVQLITLMNELRRQGLPFWIAAAVSPFKYTEPDCAYQYLKLEKKFKAGADYAITQLG
FDVRKFRELRRYLDERHIQNPVLGNVYVLGLKSAEKMSKGEPPGCWVAPELVEKIRDEVK
AKDKGEAARLERAARMIAILRGLGYAGAYIGGTHNAEHLRWIIERGQILAPRWKELADEF
TYAPKSAFYMFEPGPAAPRKLRGLSDRAVNALWHLLSPTQIPRGSILEKWARAMFAWIDR
RPTMSHFLERAEFAIKSPAFGCEACGNCVLPDMQYVCPQTCPKQLRNGPCGGTNNGQCEV
IPERSCVWVRVYDRAKHAGEIPLLRIYIPPPDRSLKGTSSW
>A0A858IW37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii|TrEMBL
MVLKNEVRDRNIRVSFEFFPPKSEEMEGQLWHTVSQLQDWDPDFVSVTYGAGGTTKAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESLDAAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFEGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSSVLDNLGLSRRQTRTAGAAA
>A0A8H5HHR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tricholomella constricta|TrEMBL
MPTPTVSIEPYVVANTGSAARDYCMLERNLLSHLKLAFLLSLLSSSLLLRARLVPEPEDS
SSETEDKASLPLAGVQIAASLATIVAGVWEYHTGYRDLRDMRAFLVGVNPHLAIMSVVVI
AIFATCIGLQNLLDRIERMRALGPEFIDITWNAGGRTSDLTSEMVKTCQSLIGIETCMHL
TCTNMPEEKVDIALREAKEHGCRNVLALRGDPPIGKEEWEAVEGGFMHGIDLVRHIRNLY
GDYFDIAVAGFPQHQLLPKEERDLELKYLKEKIDAGVSFIFTQMFYDVEIFIEWVKEVRA
AGITIPIVPGIAPIQTWNGFMRATSLAKIIIPQSFMDALEPHKNNDEQVRAIGTKLVADM
CRRILNGNLGIRGLHFYTMNLEKGTKMLLEELNLVPRVETIKPLPWRQSLTPSRRQETIR
PIFWANRAKSYISRTENWDEYPNGRFGDARSPAYGELDGYGVWIKQTKEDAIKLWGHPTT
FSDIASLFSRFCTKDLSALPWSDQAPSTETSVISKQLARMNELGFLTINSQPAVNGARSD
NKVFGWGPSNGYVYQKAYLEFFVNPALLTRLLKHIERDSNITYYVINSRGDLKTNTHSDG
PNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAYELGQQWAQIYDAESPSRKLISDLMETC
SLVNVVHNDFQDPEAIFKPFFLAGEEYRALEHVSPPLVNGH
>A0A1D2IH33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. AVP053U2|TrEMBL
MALGTPSVRTDHARTVRDMLAAGKTTYSFEFSAPKTPKGQRNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVHETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMADWIPHPQGLTYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWDTDVANFVD
KCRAGADYAITQMFFHPESYLRLRDRVDAAGCGTPVIPEVMPVTSVKMLERLPKLSNASF
PDALKERILTAADDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPLRA
>A0A0P9XE15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. mori|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VKFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A5B8SYX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc pseudomesenteroides|TrEMBL
MTKINQIYKTKPVPVLSFEVYPPHQEESVTSLFQTLEELNPRQAGVDFISVTYGAGGSAN
HERTQQIASYIQNHFGVTALHHLTGINQTPATLHHNLSEMKAAGIENILAVRGDLPSSDY
DNSCYPFAKDLITDIKKENDFSIGAAVYPEGHVDNPITGISVGGVREKISAGSQFLISQL
FFDNHAFYKMQEELKNNYIQIPVSAGILPIISQKQVEKLTYMIGSSLPAKLAKIVHKYQD
NSEALRQAGMAYAMEQIYDLLDHGVDGIHLYAMNQADILTTMLPKINDYIQCKNKRYAV
>C0QIT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforapulum autotrophicum (strain ATCC 43914 / DSM 3382 / VKM B-1955 / HRM2)|TrEMBL
MEKRFMTAKDGFKITVEVVPPAGFDPEPLLEQLVSISGLGFDGFSVATNPVAKPCMCAMA
MCSLIQGRTGKPSILHCTTRDHNRLSLQGQLWGAKALGIDTVLAATGDMVAKKERKITST
VSDLNVFQLAAMAVQSGMDTGVVFDSHPEINGFDLAVDRLRKKVDAGAGFVVTQPVYDRA
SAERIAVATQGLGIPVILGILPLRTLKHAVFLHDRVAGIAVPESVRSAMALAEDTVAEGA
SNASKMLTIARESFAGACVMPPFNHYEVLHSIIG
>A0A1Q4E0I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. 73-21|TrEMBL
MVKVTQRIDQDRPVFSVEFFPPNDEKGEAELWRAIRRLEPLDPAFVSVTYGAGGSNRDRT
IRTTARIATDTTLVPMAHLTAVSHTVAELRHVIGAYAAAGISNVLAIRGDPPGDPLGEWV
AHPEGLTYADELVSLVRRLGDFSVGVAAFPYGHPRSGDPDEDLRRLVAKIRAGADFAITQ
LFLEPDGYLRLRDRLAAVGCDVPVLPGIMPLTTVRTLHRGPELSGAPVPPALLERLEPYA
DDPASFRAAGMDVTAELCTRLLAEGVRNLHFYTLNRSLATIELVERLGLGTRRAVVSG
>A0A1B8RH14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii|TrEMBL
MVLKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSQLQDWDPDFVSVTYGAGGTTKAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRRAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPTFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGISRRETKSAGAAA
>A0A3M4LNA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cichorii|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLLTVARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
NEVKIPAAPHLSCVGDSKAELRALLAQYKDAGIKRIVALRGDLPSGMGMASGELRYASDL
VSFIREETGSHFHIEVAAYPEMHPQAHNFDNDVKNFVHKAQAGADSAITQYFFNADSYFH
FLERVQKKGVNLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1I4KY42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelosinus propionicus DSM 13327|TrEMBL
MKLSDLFIKGKTLVSFEIFPPKQSVTLESIFKTTEGLQTLNPDFTSITYGAGGSASDRTI
ETADKIKNTYGVEALAHLTCINSHKDDIDLMLNQLQAHNIENILAMRGDYPINKNNNKGT
ENTYQYAKDLIAHIKSNHDFCIAAAAYPEGHPECPDLNTDLFHLKEKVNSGTDFLITQMF
FDNAILYDFLDRIKQVNITIPVSAGIMPLLNTKQVGRIKGLCGATIPKPLQNIIEKYEHS
PLDFEKAGIEYACSQITDLVANQVDGIHLYTMNKLEQSKTIIQQTNLR
>A0A4V3B7J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus amylolyticus|TrEMBL
MKADLRKVMQERVLVGDGAMGTYLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQISALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFAELGARIIGGCCGTTPDHITAMKEALADYIPSPILEPDPSE
SKPRIVLHEHVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLEKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A840SI79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amaricoccus macauensis|TrEMBL
MASILDFVRRKPAPAAPLAVAGFIEDFSIEVMPRTASQIADFRAILPAGTRVYLAHIDGT
PMADMLATARRLTDEGFAVMPHFPARGIADRAELARRIAAYADVGVTRALVLAGGMDRPS
GAFHEAMQLLETGLFDRAGFTRLHVAGHPEGNRDIDPNGGEANVMAALARKDAFQRETDA
RMAIVTQFAFEAAPIIDWTDRMRAAGLTLPVHIGIAGPAKLQTMLKYAMMCGVGPSLRVL
QRRAADLTKLMLPFEPAEILADLARHKAANPDFPVERVHFFPLGGIGATTDWVSNARPAA
RRRA
>A0A090W279|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jejuia pallidilutea|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPKKGKNIQDLYNNIDPLMEFKPPFIDVTTSREEYVYID
RGNGLLDKRITRMRPGTVGICASIMHKYNVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKEEAYFKPCEGGHAYASELVAQIAKLNRGKYLHDDVVVESNSDFCIGVAGY
PEKHMEAPSLITDLKRLKAKVDAGADYVVTQMFFDNSKYFEFVNKAREIGIDVPIIPGIK
PIAVKRHLQLLPQVFKIDLPQDLIDAVEACKDNKAVRQVGIEFAIQQSKELLDFGVPVLH
YYSMGKSDNIKLLPKHCFKYSITFVV
>A0A0N1HFG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phialophora attinorum|TrEMBL
MHISQKLAQAASQQKPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
QLTCEMVSAAQSHYGLETCMHLTCTDMEREKVDSALRQAYKTGCTNILALRGDPPRDQEK
WEAKADQFRYAKDLVKYIRQTYGDHFDIGVAGYPEGCEDQEDPDLLIDHLKEKVDAGGTF
IVTQMFYNVDIFLDWVAKCRKRGITVPIIPGIMPISTHGAFLRRADWTKCDVPQFWHEAL
EPVKNDDAAVRDVGRDLVVEMCQKILDAGIYHLHFYTMNLAQATRMVLDDLLLTPAASGT
PIDKPLPWRQSLGLNRRDETVRPIFWRNRNTSYVARTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANIKLWGEPNTLRQVSNLFVRYLKGDLDRLPWSEGQMSAEATVIKDNLI
DLNSRGFLSINSQPAVNAAKSTDPIYGWGPKGGYVYQKAYLELLVFPSVIDEVITRLEKD
QNLTYYAVNKNGTLKTNAPDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WSRCYPAGSATRKLIEEIMDECYLVNIVNNDFHQTFEIFEIFEGLQADDFDKEFHSTAQN
GHHNGDRQVVNGDSKASEVEKAISNEPAKVPFQTALRPIENGSKAKARTTEK
>A0A1Y5DW75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp. 41_12_T18|TrEMBL
MTNKLTISCEFFPPKTDKGIATIRDVRQQLAPLNPEFFSVTFGAGGSTQDNTLDTVIEIQ
QAQATTNIDAAPHLSCVGSTAESIRNLLHTFQSHDIHRIVALRGDLPSGMRDPGDFRYAN
ELVEFIRKETGDYFTIEVAAYPEVHPQAESAHIDLTNFKRKVDAGANSAITQYFYNIDAY
LQFIDRCQQQNIDIPIIPGIMPINNFTQLARFSDACGAEIPRWLRKQLEVFHDDLESLQA
FTLDFLTDFTEKLVEQGVPGLHFYSMNRADPTLTICQRLGLLD
>A0A1I0RVP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga arvensicola|TrEMBL
MFLEKIRSGMSGILTYGITPPKEETPPERVAEIAARTMNRLVPLDIDALIVYDVQDESDR
TSAERPFPFINALDPFQFASNHLKDLKIPKIIYRPAGKFSEQELTSWLHRLEEENFYPVF
VGVPSPNYQVKTSLPHAYQIWKNHEDTSVVGAVTIPERHAKLKDEDSRILQKAACGVSYF
VSQCVFNVDYAKQMIEDLCRTCRDQQITPPTIIFTLTACGSEKTLHFMEWLGIHVPEDLK
VELKNAENMLEKSVNVCLDIAEELTAFCSEQCIPFGFNIESVAIRKDEIEASIYMVNAIG
TMLSAKGIRQTAALSVG
>A0A068REG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia symbiotica SCt-VLC|TrEMBL
MSFYHANQREALNQSLAELNGQIKVSFEFFPPRTSEMEDTLWQSIHRLSSLKPKFVSVTY
GANSGERERTHSIIKGIKDCTGLDAAPHLTCIDASPAQLRDIASDYWSSGIRHIVALRGD
LPPTDGGRPEMYATDLVTQLKDIGDFDISVTAYPEVHPEAKSAQADLINLKRKVDAGANR
AITQFFFDVESYLRFRDRCVTAGIDVEIVPGMLPVSNFKQLQRFASLTNVRVPSWMTSMF
AGLDVDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPMAAA
>A0A1M6XFC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium lablabi|TrEMBL
MTEVTSPAPDGRALHSPKISFEFFPPKTEEMERSLWETVNRLAPLAPNFVSVTYGAGGST
RERTHSTIARILKETRLTPAAHLTCVGAPKGEIDDVVARYHDVGVRHIVALRGDPTTGIG
TAYQAHPDGYQSSPDLIEGIKKRYPDIEISVSAYPEKHPESPSLDADIDTLKAKVDAGAT
RAITQVFFDNDLYFRYLDRVRAHGIDIPVVPGIMPMHNFKQARGFVTRAGTTVPSWLADK
FEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPAGAQ
KAA
>A0A8B9DY78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anser cygnoid|TrEMBL
ALYPPCSLCSPPPESSPCSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDRWFS
LEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCG
LETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVKH
IRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFLKFMK
DCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIEL
AVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILT
INSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNYHIV
NVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEE
ESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPAQQ
>A0A6I0GVZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKNGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNIEQDLYWLKKKVEAGADYVVTQMFYDNQKYVAFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAIKCKDDKEARALGIEWCVNQCRELIAYGVPGIHF
YTVGAVENVKEVATAVY
>A0A2P6NQS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planoprotostelium fungivorum|TrEMBL
MKVIDLINERIRNNQTPFYSFEYFPPKTEKGVENLYERLDRMSALEPLWIDVTWGAGGST
SKLTLEICHNAQNFCGLETMMHLTCTNISVAEVKQALDQAKASGIQNILALRGDPPRGEA
WTPGTEGLTRATDLVKLIRAEYGDYFCIAVAGYPEGHTEATSFEDDVVHLKSKMAAGADL
IVTQLFYDTEIYREYVKSVRAAGITCPIIPGVLPIQGYAGFQRMTSLCRTKIPREITDSL
EPIKNDDEMVKEYGVQLCMKMCRELIDMGSPGVHFYTLNLEKSTIKTLEGLELLSNDFAE
KPLPWASHSQIRKGKRGKEDVRPIFWRNRPKSYIDRTNCWDEFPNGRWTHSNSPAFGELT
DYHLHAPAAHKEFERREAFGRELTSVQSVFDAFAKYCAGEIDRLPWSETPLALESNAILT
RLVSMNKRGFLTINSQPRVNGAASTDEVHGWGPKGGYVYQKVRKAYLEFFTSPENFSTLQ
EVLKHHPSISFHAVDRSGKSTSSYNKPSTTAVTWGVFPGREIIQPTVVDSESFLVWKDEA
FALWTTQWISLYKAGSQSVQILEQVRDTFYLVNIVDNNFVDGNIFDVVDEVLKASGRAAL
TESKG
>A0A354GM27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetales bacterium|TrEMBL
MHIQDIFAEHRTTFSFEFFPPKTDAAWEDLFANIARLQALQPSFVSVTYGAGGTTRERTH
DLIVRIHRETNLTAVSHLTCICHTHDELSAILDRYAASGIVNILALGGDPPRGQADYDRA
KDAFAYADGLVRFIKSRTLPGDSRGFGLGVAGFPEGHPATPNRLKEMDYLKQKVDAGADY
ICTQLFFDNRDFYDFRERCDLAGIKVPIIAGIMPVASRSGMVRMADLALGARFPAALLRA
IGRCADDEAVAKVGVHWATEQCRDLLDHQVRGIHFYTLNRSDATRQIYENLGVKDSAALR
VGSGR
>A0A3N4FN25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia mallei|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A127M1C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zhongshania aliphaticivorans|TrEMBL
MANRYSFEFFPPKTEVGRAKLKDTRSQLAALNPEFFSVTYGAGGSTRDNTRDIVLETKKA
GLSVAPHLSFGGDEESEILTLLNDYKAAGIDRIVALRGDIPSGMGATRQVYAKELVEFIR
KHTGDHFQLEVAAYPETHPDAKSHQADIQFLKAKLDAGANSAITQYFFNADAYFYFLEDC
EKAGIDKPIYPGIMPITNFSNLARFSRNCGAEIPRWLAQKLEGYGDDQQSIIEFGAEFVS
ELCHILMEGGAPGIHFYSMNQVEPIKSIAEAVMSSHPAG
>A0A0Q5GS39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. Leaf131|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAAKLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGNRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDT
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
ATLCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A374DPA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM34-10LB|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYGAGGNGSKNRT
CEIASKIKRDFGVESVAHLTCINSTKADIDSNLALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A6B2L0D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcella intermedia|TrEMBL
MTSRKIVDMIKEKEEKNETFFSFEYFPPRTDRGVQNLYARLERMAQYKPLFIDVTWGAGG
STSALTTEICIHAFKYYGLETNMHLTCTNMPVEKIDAALKEIKDVGIRNVFALRGDPPKG
EEWKQVEGGFAHAADLVKYIRQKHGDWFCIGVAAYPEKHVDCDTYENDLLHLKAKIDAGA
DYIITQLCYTSEAYLKFIKDCRNLGINVPVLPGIMPIRSYQGTIRMCKLCGANLPKKVLE
DMEPFKEDDERVQSYGIDQSVQMCNELIAGGVRGLHFYTLNLDHSVKLVLLKMNYIKDVQ
CKRELPWGGARTTNNSQKSEAVRPIFWANRPKSFISRTDMWDEFPNGRWGDAGSPAFDTL
STYHTSNLYTNSIDTRKQEWGSPESEDDISKIFVSYLKGVISRLPWNDATLSEESNAISD
VLQAMNINHFWTINSQPKVNAVSSEDHVFGWGPVGGYVYQKAYVEFFVSPEKFLKLKSLF
SKYPSLDYQAVNAQGDGEGTFKGITAVTWGVWPSSEIKQPTVVDPDVFTNIWKDEAFALW
KSQWGSLYEPNSVSFKLIEKIANTFYLVNIVDNNFISGNIFAIFEDLLEIKN
>A8AKX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2G6V634|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 2|TrEMBL
MKVTEHIENAKGKTLFSFELIPPQKGKSIQELYDNIDPLMEFQPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNHFAIDLVKQINDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFAFVEKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVYKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A1I1TH32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivivax sediminis|TrEMBL
MQRPDISLEFFPPKSLEASFRLWDTVQNLAPLGPRFVSVTYGAGGTTRELTRDAVKAIHK
HSGLRTAAHLTCVNATREETLGIATEFWDAGVKDIVALRGDPPKGQERFTPTDGGFESSP
ELIAALKDTRDFTVRVGAYPDIHPNAGSMDDDVQFLKRKFEAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGIFPVENWKGARRFAEGCGTKIPQWVIDAFEKAERDGHTDLLAK
SLCTELCSELIDGGVDKLHFYTLNKPELTRDVCHAIGVTPETRLENVA
>A0A0A2L861|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium italicum|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEAAENGFCYAKDLVKYIRNKYGNHFDIGVGGYPEGADDNTDVDQLIDHLKEKVDAGSSF
VVTQMFYDADNFIEWLKKCRAKGITVPIIPGIMPIQTYASFIRRSNWTKVRVPPQWMEAL
EPVKNDDSAVREIGKTLIADMCRQLIAAGIKHLHFYTMNLAQATQLVLKELDLSPSDESP
IQRALPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISEIFVNFLTGKLDRLPWSDSPITTEAQDIQEDLLK
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKNN
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCHDAASPSRKLIQNVMDDWYLVNIVDNDFHRSNAVFELFNGLEIKDLNVEVAGKPLTNG
HAEQNGVAVN
>A0A0S8D0N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira bacterium SG8_35_1|TrEMBL
MLVKDILNSKKTCISYEFFPPKLESDWDRLFQTISDLIPLEPAYVSVTYGAGGSTRDRTH
DLLVRIQEETDLTVVSHLTCVGSNRDDIHAILKKYSDHGIENILALRGDLPKGQTQWETP
ENGFPYAADLVAYIKKHFPRMGIGVAGFPEGHPETPNRLKEIEHLKAKVDAGADYIVTQL
FFDNRDFYDFRERCELAHINVPIIAGIMPITTRQGMIRMAELAAGARIPARLLKSVERAG
SDEYLERVGVHWATEQVRDLIDNNVRGIHLYTLNCSTATLRIYKSLGISSSIQLSM
>A0A242BTT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus sp. 5B3_DIV0040|TrEMBL
MSSTLSFEVFPPNTQIGTEKLFKTLKELQQLEPYFISVTCSNNRQTIEETTLKFADYIHR
KLKIPTITHLPAAYLNQSQLAELVKRLNQIGINQILALRGDIIPDLPPKKDFVYASDLIQ
YVKKEAPHLHISGACYPETHPESLNRIEDIKQLKHKVSVGCEQLVTQFFFDNDLFYQFQE
SCYLADIKVPILAGIMPIVNRNQALRLIKTTNTKLPRKFLAILEKYEHDPVALREAGLAY
AIDQIVDLTTYDISGIHLYTMNNAEVAKHIYHNTKNVLNGQFKEGEFI
>A0A1H0ES61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. cf386|TrEMBL
MALGTASIRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGDWVPHPSGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAAGCDTPIIPEIMPIASARTLERIPSLTNAAF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A1I7MWF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium facile|TrEMBL
MLRIAPARRGSRFLGQGDIDVSFEFFPPRTAVMEKSLWRAIDRLGPLRPTSVAVTSGIDG
TTRERTRVTVERILRETTLAPAVHLTRVGNTRAEIAETAAAYWNLGVRKLVALQGDASTG
DRYELGPDDYEYTCDMVADLKGIANFEITVAGYPEKHPAAGTVAADIAALKDKVDAGADR
IITQFFFDNKLFFRFEEQARTLGVEAPIIPGILPIHNFKQVAAVAARCGVSIPSWLVRRF
EGLENDPETHRLAAAAFAAEQVLGLVDRGVAEFHFFTLNRADLVYGICHMLGLRSAEVA
>A0A7W9AXY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella daejeonensis|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDIEPAAHLTCVDATRDDVDRVVREFAALGVSRFVALRGDPAAGIGE
KYVPTPDGYQNGADLVAGLRGIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIIPGMLPVHNFKQVRNFCSRSATHIPAWLAERFE
GLENDPQTHQLVAAAVAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKAEAAL
EVA
>A0A1K2FS74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. F-1|TrEMBL
MREILAGGKKTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVKE
TQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVPHP
RGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDTDVAHFVDKCRAGADYAITQMFF
RPESYLRLRDRVADAGCDTPVIPEVLPVTSVKMLERLPKLSNADVPDALKERILAAKDDP
AAVRSIGIDFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>A0A1H1DH29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia tuberum|TrEMBL
MNPIELSFEFFPPKTQEGIDKLRATRAELVSLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHLSCIGSSKDSLRAILNEYRAYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARQLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTALCQRLVDAKVPGLHFYTLNAARVDQGDLRTARRVIAMPARLQRPRGPRQSGMGRKFV
PNSVVSPC
>A0A4Q4DS33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. L-9-10|TrEMBL
MAAETADLSQHPRPGPRALMADGQRSYSFEFFPPKTPAGERTLWNAIRRIEALAPSFVSV
TYGAGGSSRDRTIEVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGIRDVLALR
GDPPGDPRGEWVRHPEGFAQASELVGLIRELGDFTVGVAAFPERHPRSPDWDSDIRHFVA
KCRAGADYAITQMFFDVEDYLRLRDRIEAAGCTTPIVPEIMPATDARQISRFAELSDARF
PDALAQRLEAARDRPQDGHRIGVEYATAMAERLLAEGAPGLHYITLNRSTATMEIHQNLG
VGVRRDRPLAASRP
>A0A4Y9YK94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fomitopsis rosea|TrEMBL
MKISQKIAQAEKEDRIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSELVKTCQKLIGVETCMHLTCTNMPKEKVDIALEDAKAHGCRNILALRGDPPMGKDE
WEAVEGGFVHGIDLVRHMRAHYGDYFDIAIAGFPQHIQLPPAELALEMQYLKEKVDAGAE
FIFTQMFYDVEMFIAWVKAVRAAGITVPIVPGIAPIQTWNGFIKSTSLSRTEIPKKLLDA
LEPYKSNDEKVREIGTKLVADMCRRILSEPLGIKGVHFYTMNLEKGTRMLLEELNLVPRI
QTIKPLPWRQSLTPNRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQSKEEALQLWDHPTTVIELGKLFGKFCVGQLAALPWSDQAPSSETSVIATQLA
KLNEMGFLTINSQPAVDGARSDDRVHGWGPSNGYVYQKAYLEFFVSPELLNALLPHIERD
VNITYYVINKRGDLRTNTHSDGPNAVTWGVFPNKEIVQPTIVEAISFMAWKDEAYELGRQ
WAKYYEPSSPSRALIDNVMDTYFLVNVVHNDYKRPEAIFESFFKAGAEFATAHGAAPSVL
NGH
>A9BD12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus (strain MIT 9211)|TrEMBL
MISDSNYLIRKQLDSVLQYALESEGAAITAEIMPPRGGDPSHAIAMASKLSDRVHALNVT
DGSRAIMRMSSLAVCKLLLEANLEPVLQIACRDKNRIGLQAEILGAHALGIKNVLCLTGD
PVKAGDQPNARPVHDFESVQLLKQVAALNRGEDPVQGQLPNGRTALFAGAAADPNCKNLN
SLLKRLERKKLAGAQFLQTQMVMNSRVLERFSKEIADPLEFPVLAGVFLLKSAKNAAFIN
KVVPGACIPNSILARLDNAHEPIKEGITIAAEQVKSFLGITKGVHIMAIRAEHLIPQILD
QANVKKLNQ
>A0A2P6C918|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter butkevichii|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFKPPFIDVTTSREEYVYLD
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKDEPYFKPVKGGNAFATELVGQIANLNRGQYLHDDVLVEHYSDFCIGVAGY
PEKHMEAPSLVSDLRRLKEKVDAGADYVVTQMFFDNNKYFEFVKAAREMGINVPIIPGIK
PLAVKRHLQVLPQVFKIDLPQDLIDAVDGCKDNKAVRQVGIEFAIQQSKELLAAGVPVLH
YYSMGKSDNIQAIASELF
>A0A5C4QAV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurellaceae bacterium BK431|TrEMBL
MSYAKEIDHLNHSLANLNGEINVSFEFFPAKNEKMETLLWDSIHRLAPLKPKFVSVTYGA
NSGERDRTHGIVKRIQQDTGLIAAPHLTGIDATPDQLRVIAQDYWDSGIRNIVALRGDEP
PGYAKQPFYASDLVKLLKEVADFDISVAAYPEVHPEAKSAQSDLLHLKEKVAAGANRAIT
QFFFDVDSYLRFRDRCVAVGIDVEIVPGILPVTNFKQLQKMATLTNVKVPSWMPKMYQGL
EDDQTTRNLVAASIAIDMVKVLSNEGVKDFHFYTLNRSELTYAICHMLGVRAAV
>A0A2X3LMR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. Ea1.12|TrEMBL
MRESTASHERPARDFELICEIEPPTRPDLTHARHQIGVLSPVTDAFLIPDNHIGRATVSS
IAVAHEVQTMGGRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVHGDKPTAGNRTSDL
TVRAMIDEARAASEDPVFADMPAFRVGAAAGVRPLPTWKRAADFLFVQVSYSVDALLRWR
DAHPVELPVYAGVMVLASAGMARRLAATIPDIDIPDDLVHAVERDRTAGVETACDQVLQL
RDSGAFAGVHLVPVSRYRQVATRLEDLL
>M0MT00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halococcus salifodinae DSM 8989|TrEMBL
MSVARSAATVDGATDLLTDLRFELMPFDSFEGQMDHLPDGATIAITTSPQLGLDATIEWA
EKAAERGFEVSPHIAARYVRDEDHLEEIARRLTDAGITDIFVPGGDREEPAGEFASAYEL
LAALDDLDYEFDEVGITGYPEGHEFLDDATLAEAMKKKAPYATYIVTQLCYDPDAVVEWI
EAVRDRGVDLPVEIGIPGVMKYQRLLKISQKVGVGDSVRFLKKTTGILGFVRQLVGSRGK
YTPDDLIDGLAPYADDPHYDIDGLHLYTFNQTSDTESWRYGRLEE
>A0A7V3L4C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MVSGSRLERLLRQGEFVLCGEMSPPQGADKAAILKKCDYFRGYVDAVNLTDNQTAIVRMS
SIMSSVFVLEGGCEPIMQMACRDRNRLAQQSDLLGAYAAGIRNVLCLTGDYQTFGNQGDA
KGVFDLDSVQLIHTVADMNAGTLLSGDELKPPPAFFIGGAANPFAEPLEMRIIRLAKKIQ
AGAHFIQTQPVFDWPKFEKWMSAVRDAGLDQKVFIIVGVMPVRSVKALLYMRDEVPGMSI
SDECIKRMESAQDPKEEGVRMCVETMQRLRETPGVRGIHIMPVMWESITPRLVEEAGFLP
RPEPLPTEQVTAEATETN
>A0A7H5FHD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia sp. MM1IDA2H-1|TrEMBL
MSASEHPSGISFEFFPPNTEVGREKLMGVRDRLAALDPAFFSVTYGAGGSTRERTFNTVQ
SVRSSGICTAPHLSCVGSDRGELREILGEYREQGIKRLVALRGDLPSGMGARSELRHANE
LVEFVRDETGDHFEIAVAAYPECHPQADNYRMDLENFARKMNAGADIAITQYFFNADAYF
HFVERARDLGIQQPIIPGIMPITNYTKLARFSDSCGAEIPRWIRRQLESYADDSESLQAF
GTEVISRMSQRLLDGGAPGLHFYTLNQAGPCLKVLENLGISSR
>A0A2G5XLB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. P19|TrEMBL
MSLLDKLQTNVLTADGAMGTILYSYGIDYCYEELNVEKPEIIEQIHQDYIAAGADIIQTN
TYSANANKLARYGLESRVTEFNKAAIQIAKRAAAPGGQFVLGTIGGLRGIRKSDATLDEI
EKVVLEQANALLAGDPDGLLLETYYDFEELSSVVTTLKKITDVPLIAQVSMHDPGVLQNG
LSLNDALHQLESLGADIVGVNCRLGPYHTIQAFDNVTLPEKAFLSAYPNASLLDVEDGRI
VYESEAEYFGRAAVLLRDQGVRLIGGCCGTTPKHIKAAKTQLARLAPITEKVVHPEKPIV
IHEAGPTKHQPLHEKAKTERTVIVELDTPRHLETEDYIKGANVLYDAGVDAITMADNSLA
SPRISNMAMGSIVKMKHNIRPLVHLTCRDHNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELLQLIKKLNEGISFSGKPLRKKANFSISAAFNPNVRVIDRAVQR
LEKKIEAGADYFITQPVYTKEKIIDVYEATKHLDTPIFIGIMPLTNIRNAEFLHHEVPGI
KLSEDVLERMRECGDDREKSTETGLEIAKELIDTAAQYFNGLYIITPFLRYDMTLELYEY
IKEIDQKKKERELTHAETSY
>A0A7C2V2Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MPAREGSPYAVYTQSGTGAACGGRKTRKIRGANWYNSPAMIREAFRERLAQGPLVADGAL
GTMLALRGVPQPYELANLTHAEVVRALHREYYEAGARLIETNTYFANRVRLLNLPERGSE
LPPAFSLLEQFGSPDELVRRINRAAAQLAREAVGDDALVFGAVGPVGKPLEPMGEVRRAE
AEQAFEEQIRALLEGGVDGLILETFIDPQELALAIRVARRLAPDAPIIASKGFVEDGETL
MDGLPERFAEQIQPLDVDAIGGNCIVGPQRMLDIVRMMAQATELPISAMPTPGLPQLVRG
QVVYDIHPDYFGKYAARLVEAGATIVGGCCGTTPAHTRAIAQYARAAKTKPRTVVAVRTR
ERAPKEELPTAEPSRLSHLLGKERVITVELDLPRGLKIQKVIESARLLKAHGVHMIDISD
GARARLRMNVIATSHIIQRDAGIEVMMHFACRDRNLLAIQSDLLGAHALGIRNVLAITGD
PAQIGDYPTATSVFDVDAIGLVRILRRFNEGRDLAGNSIGVYANFTIAAAYNPLAPDLDA
ENDRLRRKIDEGAHLIYTQPLFEMPVVERTAELLQRLRTPWFVGVLPLRSARHAEFMHNE
VPGIEIPEPILQRMQDAPEDSALQVGLEIAQEFVRQADPYAQGLYLMPPAGSAQIALKVL
EGLG
>A0A7Y5E136|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polyangiaceae bacterium|TrEMBL
MLKPSFLEALSRGALVADGAMGTQLYERGVLYSVCFEELNISRPELVTKVHEDYVRAGAT
VLETNTFGANAMRLEKHGLQGRVKEINTAAVALARKAADGRAYVVGCIGPSGYFLGDASP
DDVAKVKGALYEQAVALCEAGVDALVVETFRQTNELRVAVEAALAAAQGKIPVIGSASVD
ENNRMSDGTTAGEMARLLRDWGAQGAGINCSDGPMNVLAAAEEMLAAGIPIWALPNAGLP
RRVDERMVYVSTPEYFGVYARRMYKLGVKVVGGCCGTTPDHVKRIAAAARMVGKDDAEPM
EGGEPDTNRFTPSILPTAASQPVPWAERSSITKKIAAKRFVVSVEVNPPVGLNPQKALDA
ARMLKAGGIDVVNIADGARAQARMSNLSMATRMQNEVGVDTILHVCGRDRNLLATLAHLL
GAHDQGIRNLVIITGDPPKMGDFPDATAVYDLDSIGILKLAKRLNHGIDPGGKPMGDVTS
FLLATGAEPAALNYPRELSRLIQKKEAGAELVMTQPVYDPAVLNRFLDDIEPLGLPVLVG
LLPLASHRNAEFLHNEVPGMQVPEHIRDRMRKAGTGVQARKEGVAIAREMLSAVRSRVAG
AYIMPPLERYELALEVVDGFLDP
>A0A7D7VT33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MSKNNISTFTCFYHRIRGDAVKSEIYFRPEKDGHHFAGELVSQIQDMNKGSYLDEDLLNT
SKTNFCIGVAAYPEKHVEAPSLDSDIHFLKKKIKNGAEYIVTQMFFDNQKYFDFVAKCRK
EGITAPIIPGLKPITTKKQLNLIPHRFHVDLPDDLIMSIVKCKDNKAVREVGIEWCIAQS
KELVNRGVPILHYYSMGKSASIYEVAANIF
>A0A7C3MVR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MRPGRPPTNQRGKPGIGAAGRLRLLTEETELPTLTSLVGTGIVVCDGAMGTQLHERGIPF
GHPYEYANLTHPELVTAIHTEYLRSGAVIIETNTFGANRMKLAAFEREGLVSEINEAGAR
AARKAAGRSALVAGAIGPMGKPLKPLGRVDPEAAAEAFREQALALLGGGVDLFILETFAD
LEELHLALQTVRELCDLPVIVEKAFVEDGETLSDGLPARVAQAVTEWGPDGCGANCAVGP
QRMLEIVHMMASTTTLPVSAMPTAGLPQLVNGHVHYNATPDYFARYGRMLVEAGATLVGG
CCGTTPEHIRALSTAIRGMTIRPRPAADVTPAVPRRAAEPAPPKPAVERSRLAQKLGTKY
VVAVELDLPRGTSIQKVLDGAASLRDAGCDIIDISDGARARLRMNPIAVSHLIQEQVGIE
VMMHFSCRDRNILAIQADLMGAHALGLRNILAITGDPTQVGDYPTATSVFDIDAIGLVRV
LSRLNEGVDLAGNSIVEPTAFLIAVAFNPVAPDFASEVDRLKRKVDAGAQLVYTQPAYEI
GAVERAAEETRKLNVPMLVGVLPLRSSRHAEFFHNEVPGIYIPDEIRTRLAAASDQEARA
IGMEVARELLAAARPMTAGAYLMPPFGNHKIAEELMAAIS
>A0A6J3JQ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sapajus apella|TrEMBL
MDLRKARVLPAGHYCPSLGIRASQAGSVRFSVPPSISRNPAMVNEARGNGSLNPCLEGSA
SSGSESSKDSSRCSTPGLDPDRHERLLEKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCHQRLEEIT
GHLHKAKQLGLKNILALRGDPTGDQWEEEEGGFNHAVDLVKHIRSEFGDYFDICVAGYPK
GHPDAESFEADVKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDIGITCPILPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVRLCRELLASGLVPGLH
FYTLNREVATTEVLKHLGLWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKNYYLFYLKSKSPRDELLKMWGEELASEESVFEVFVHYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGVLTINSQPNINGKPSSDPIVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPGLQPNAV
TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRAIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDTLELLNRPTQHEREAEAP
>R8W1Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus pullicaecorum 1.2|TrEMBL
MELREYLKHKTLLFDGAMGTYFRSVHPEYPGKCELANCNAPAKVAEVHKNYLESGARAIK
TNTFAANTHALECKFDEVRTVIRQGWKIATKVAEPYRAFVFADIGPITDPNGEYEQIVDE
FLALGAKNFLFETWSDDDDLYALAAYIKARCPDAFLIASFAVSPDGFTRQGLSARAVLER
VTNCPVIDAAGFNCVSGPNHLLAQARANADLFGKERPAADPAMLSVMPNAGYPTIVDGRT
FFENRAGYFASRMVEIVAAGAKIIGGCCGTTPEHIRLTAEALNEEEIKPEPAAAQVEVKP
REVKNRLADKFAAKKRVIAVELDPPADDNLEKFMAGAKALKEAGVDAITIADCPIARARA
DSSLLAAKLRRELDIDPIPHMTCRDRNINATKALLLGLSAEEVRNVLVVTGDPIPSAERD
EVKGVFSFNSAVLAGYIRELGEQGVTASFRVFGALNVNAANFEVELRKAKRKVEQGVAGF
LTQPVFTSRAFENLIHAHEELDADILGGVIPIVSHRNALYMNNEVAGIEISQGVINRYEG
LDREAAEDLAVDLSVQLAQRMEPYTAGWYFITPFQRVSLITRILRELNKSTETDPS
>A0A285JVF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes atraurantiacus|TrEMBL
MLLDDFSLEMTGKDVGELAGARVALPPGTRINVTFLGHEDLAARLAAAHAVRAAGFIPVP
HVSARRLASRQMLEEFLAALRTAGVSDEVFVVSGDPSDPHGPYPDSLSIIESGLLERYGV
RRASIAGYPEGHPDIPYDILWEALTGKSAALRKRSLDGDIITQFGFDTDPVLDWIAAVRE
RGIDSPVRIGVPGPAGVRRLLRYAARFGVATSTSIARKYGLSITNLVGTAGPGEFLRTLA
TDYHPETHGQVKLHFYTFGGLQATAEWIRDFAF
>A0A523PW90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MRCSAHQNGNPSPTNQKSRWKAQFVRTQGGNAYASELVEQIQKFNGGEFLHQKMENSSFD
GFCIGVAGYPEKHLEAPSKKSDLENLKLKVDAGADYVVTQMFFDNQKYFDFVKSAREIGI
DVPIIPGIKPLSIKKHLQVLPQIFSLDLPDQLISEVVKAKDNDAVREIGIQWAIQQSKEL
MAAGVPTLHYYSMGKSDNIYKIAKALF
>A0A101W390|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gracilibacter sp. BRH_c7a|TrEMBL
MNIDKLFEQKKAVLSFEIFPPKQTTSIDVIYDTIDALAPLRPDYISVTYGAGGSTSKTTV
EIASIIKKKYNISSLAHFTSYNSTKVEIDEILTRLGEEKVCNILALRGDKPQGAPDDYDA
KPRDFQYASDIARYINDNHKFCLGGACYPEGHPECPDLEKDVQNLRFKVEAGVSFLITQL
FFDNKVFYRFMEKVQKHNINVPIQAGIMPITNRKQIERIVQMSNAKIPEKLIRILDKFEH
NSEAIKDAGIAFATEQIVELLANDVRGVHIYTMNRPQVAKEMMRNLGSLFYTINT
>E4RIR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium hydrogeniformans|TrEMBL
MKIKKIFAEKKLVFSLEVFPPRNDVPIEDIYQTLDELQGINPDYISVTYGAGGGVNKNRT
VEISSLLKEKYGIESLAHLTCINSTRKTLNQIIDDLKAKNIENILALRGDHPDHGKEIGD
YNYSYQLVDHIKQKGDFGVAAACYPEGHLESDSLEEDIIHLKQKVDHGVDYLITQMFFEN
ELFYKFREKAAAKGIDVPIEAGIMPVINKRQVSRIIELSDAYLPKKFTKILDKYGDNDEA
LRDAGIAYAVEQIVDLIASDVDGIHLYTMNNPYVAKKIKDAVGSLIDYINVEKAD
>A0A5C6KNQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIKAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNTIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A2A4R436|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIQQAKGKTLFSFEIIPPQKGQNINDLYANIDPLMEFKPPFIDVTTSREERIYLD
KGNGLLEQKITRMRPGTVGICAALKYKYDVDAIPHVLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDAMKHEQYFNPVNGGNHYAADLVRQISDLNKGKYLHEIIETPHKADFCIGVAGY
PEKHMESPSMDADLRRLKQKVDAGADYVVTQMFFDNQKYFEFVAKAREIGIHVPIIPGIK
PIAVARHLQVLPQVFKLDLPDVLVQEIELXKNNKEIRQVGIDWAIQQSKELIQAGVPVVH
FYSMGKSSNIYAIAKEIF
>A0A3D9RP21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus taihuensis|TrEMBL
MEQMLRDKLLARKPGLISYGMTPPKATHTPEKIAEIAQKQCERLRDLDLDALILYDVQEE
ADRIEQERPFPYLQTVSPDTYSKQYLNELHVPKIIYNCVGNYSREAFIDWARKDADQDRY
SVFVGSSSSKQQVHLGLSDAYQLSEAHNDNLIFGGVVIPERHLSKQDEHLRVVSKMKNGC
DFFVTQAIYNVEASKNFLSDYFYYCSENGIDMVPILFNLAPCGSTKTLEFMKWLGISIPK
WLENDLKYSSDVLDQSIRHCQKIFEEILEYGIEKGIPIGCSIESVSTRKVEIDASVELVK
NIKSLLGKKLGSSVV
>A0A0Q8PHR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora sp. Root187|TrEMBL
MPHHDPPQLGAPTAGEPTYSFEFFPPRTELAERRFWNALRRVEAVGPAFVSITYGAGGSS
REKTVRIAERIATETTLTPVAHLTAVGHSRAELRNIIGQYADAGITDVLALRGDPPGDPR
GVWRQHPEGFRHAAELVELVRATGRFRIGVAAFPEGHPRSPDPDTDLRHFVDKCRAGADY
AITQMFFRVEDYLRLRDRVAAAGCPTPIIPEIIPITDHGQLARFAELSGATVPGELVDRL
ERCRDDAAEVRRIGLAHAVEMSARLVAEGAPGLHFITLNRADDALEIHRAVRTTATGRHP
MSA
>A0A1X1G525|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. tigurinus|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGIQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2E1EQ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVIEHIKKAKGETQFTFEILPPVKGIHISSIFDNIDPLMEFKPPFIDVTYHREEYVYND
SGNGLLQKKVVRKRPGTVGICAALQNKYNVDAIPHILCGGFTKEVTENLLIDLDFLGINN
VVALRGDAIKSETYFTPNKEGHSYASDLVNQISDLNKGIYLEDLEISSKTDFCVGVAGYP
EKHMEAPSLESDIHFLKNKIKLGADYIVTQMFFDNKKFFDFVKICRKEGINVPIIPGLKP
ISTLRQLNILPHRFHCDLPEELIKEVIKCKDNNEVKKVGIEWCIKQSKELKKAGVPFLHY
YSMGKAKSIKSIASQVF
>A0A411XZ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzae|TrEMBL
MPSHTRAITDAYSLEVSVKDIGALTKAAPRLLPGSSMFIPYLPGQHDAARLAAAQLVRSL
GFEPMPHLSARRIGAPEELQTFVARLVDEAGVTRCFVIAGDPSTPKGPFADSLSLIETGV
FERSGIRTIGVAGHPEGHPIMRTAEQWDVLERKCRSIQERGMAPLIVTQFGFDADMVVTW
VEALRARGIPHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGNAGPDR
FVDRLASRLTDAHGDIRLHVFPFGGIAQSVAWVAQYRSRASSQDRISSVRADQA
>A0A2G2M152|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robiginitomaculum sp|TrEMBL
MSLAFSSPNDTRDIEVSFEFFPPKTEQAEANLKAAVQKLAPLAPGFVSVTYGAGGSTRER
THRTVVSMAKTTGLNVAAHLTCVGASKADVDAVARAYHQAGITAIVALRGDPPDGAGACY
EPHPGGYAYASDLIAGLKRIADFDISAAGYPEMHPESPDWAAEIENLKRKVDAGASRIIT
QFCFNPDTLIAYIERVRAAGINLPIIPGIMLQPNFTGLKRMAALCKTQVPDGMHAMFEGL
ENDEPTRRLLAASIAANYCTRLQQEGLRAFHFYTLNRADLAYATCRVLGLRPHNTGETP
>A0A2L0F9Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
MSPTRPAAPFLDAIQRSILVFDGAMGSLLYERGVFVTQNFEQLNVARPELVKKVHADYLA
AGANVIETNTFGANRFRLERYGLVDEVRRFNLAGARIAREVAGADAYVAGSIGPTGLVPG
VAARDDLTAASATFAEQAGALAEGGADLLALETFRHLDEIKLAIEAAREAAPGLPILASM
TFDTNGAVADGSEPERVAQTLRDWGISLLGVNCGDGPQLSLAMAERMAAAGLPLCVQPNA
GLPRTVDGRLLYMATPEYFDVFARRMIQAGATMIGGCCGTTPEHVKWIAKSARMLRGTAA
RDDVWPAARPRISIDTPAGIEPTPLAERSPLAAKIAAGKFVVSVEVNPAPGLDPEGALSA
AKMLIDSGVDVVNVADGPRATARMTNLAFCSLLLQRYGIEPILHVCGRDRNLIGQMAHLL
GAHAIGIKNLVVITGDPPKVGDYPEATAVYDLDSIGLLHMASTMNRGLDPAGKPIPGGKT
SFLLATGLEPGAPDLDKEVARLERKRAAGADIIMTQPVFHQDLLEKVLRRIEHLEMPVLV
GVLPLVSYKNAEFLHNEVPGMQIPEEIRERMRKVPAGPEARKEGVKIAREMLFSVRDRVQ
GAYLMPPLGKYELALEVLDGLKAS
>A0A7W4W5Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litorivivens lipolytica|TrEMBL
MSKRYSFEFFPPKTDVGREKLQTVRAELNALGPSFFSVTYGAGGSTRDNTLGIVKAMKAE
GLSVAPHLSFGGDDEASMLDLINTYKDAGIDRIVALRGDLPSGMGATRLVYAKELVEFIR
KHTGDHFQLEVAAYPEIHPDAKSYQADIDFLKAKLDAGANSAITQYFYSIDAWHYFMDHC
QKAGIDKPIYPGIMPVTNFANLARFSRNCGAELPRWMTQKFESFGNDAESAKDFGIDVVT
RLSEQLLEAGAPGLHFYTMNTVEPVRSIWNNLGL
>A0A838LGQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas chungangi|TrEMBL
MMPTMSELEEARRALDAPLFADLAGDAQVSFEFFPPKSEKMEAQLWDAIQTLSPLGPRFV
AVTYGAGGSTRERTHATVARIASETAIPAAAHLTCVDATKEEVDEIARAYWEAGVRHIVA
LRGDPPRAGESFEQHPGGYRNAADLVAGLRKIAPFEISVAAYPECHPDSLSVAADLENLK
AKIDAGATRATTQFFFEPECFFRFRDKVAAHGMDIEILPGIMPVTNFAAISRMAAMNGTA
VPSWMGRLFEGLDDHPAARQLVAATVAAELCRKLYAGGVRHFHFYTLNRAELAFAICHLL
GLRANAKALEKAA
>A0A3B0UVH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MNKQAAEMDRDIIDPTAPLPKLEGHVSHTRFERVLRAGQFAVTTEIAPPDSADPAEVVRR
ADLFSGVVDAINATDGSGANCHMSSLGVCAILTKNGYSPIIQMSCRDRNRIAIQGDVLGA
AAIGVGSVLCLSGDDVSVGDHPEAKPVFDLDSISLIKTIKTMRDKGQFLSGRKLDKPPSQ
FIGSTINPFAPPLKNRVDQLAKKIDAGAEFIQTQYCFDIKMLQSFMKRAVDKGLTERAFI
LIGTGPLASARTALWLKKNIPGIHIPDAIVDRLERAENPKLEGRKICVELMARIKEIEGV
KGVHVMAYKQESHVKSIILESKVLGERQPWARSNPKVFRN
>A0A150PFC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
SEPERVARTLRDWGVDLLGVNCGDGPQLSLAMAERMATAGLPLCVQPNAGLPRTVDGRLL
YMATPEYFDVFARRMIQAGAAMIGGCCGTTPEHVKWMAKSARMLRGGAVPEVTSRPHVTM
DAPTGSEPTPLGERSPLAAKIAAGKFVVSVEVNPAPGLSPESALSAAKMLIDNGVDVVNV
ADGPRATARMTNLAFCSLLVQRYGIEPILHVCGRDRNLIGQMAHLLGAHAIGIKNLVIIT
GDPPKVGDYPEATAVYDLDSIGLLHMASTMNRGLDPAGKPIPGGKTSFLLATGLEPGAPD
LDKELARLERKRAAGADIIMTQPIFHQDLLEKVLRRIEHLGMPVLVGVLPLVSYKNAEFL
HNEVPGMQIPEEIRERMRKVPAGPEARKEGVKIAREMLFSVRDRVQGAYLMPPLGKYELA
LEVLDGLKTS
>A0A2G5ZGA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. P29|TrEMBL
MSLLEKLQTNVLTADGAMGTILYSYGIDYCYEELNIEKPEIIEQIHQDYISAGADIIQTN
TYSANANKLARYGLESHVTEFNKAAIQIAKRAAAPGGQFVLGTIGGVRGIRKSDATLDEI
EKVVLEQANALLAGDPDGLLLETYYDFEELSSVVTTLKKITDVPLIAQVSMHDPGVLQNG
LSLNDALHQLESLGADIVGVNCRLGPYHTIQAFDNVTLPEKAFLSAYPNASLLDVEDGRI
VYESEAEYFGRAAVLLRDQGVRLIGGCCGTTPKHIKAAKTQLARLAPITKKVVQPTKPIV
IHEAGPTKHQPLHEKAKTERTVIVELDTPRHLETEEYIKGANVLYDAGVDAITMADNSLA
SPRISNMAMGSIVKMQHNIRPLVHLTCRDHNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELLQLIKKLNEGISFSGKPLRKKANFSISAAFNPNVRVIDRAVQR
LEKKIEAGADYFITQPVYTKEKIIDVYEATKHLDTPIFIGIMPLTNIRNAEFLHHEVPGI
KLSEDVLERMRECGEDRERSTQTGLEIAKELIDTAAQYFNGLYLITPFLRYDMTLELYEY
IKEIDQQKERELSHAETSY
>A0A8J4YPZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nymphon striatum|TrEMBL
MIPQKDYLILHDSVVGTAKESKVDLSWREEPIQNRITRALVKGIDQYIVEDVEEARQAAD
KPIEVIEVSLMTGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPYIEEEKLLNPQEG
DTDCVVLACNNYEIVDLGVMVPPEKIIAAAIEHNVDVIGLSGLITPSLDEMVHLAKEMER
KNFSVPLLIGGATTSKAHTAVKIDPQYSQAVVHPNQLGIQVIEDMDLEKLVPFIDWTPFF
RSWELHGKYPDILTDNVVGEQATELFSDAQKMLKEIIANKKLKAKGIFGLFPANSINDDD
IEVHADEEYVFRTLRQQLKRREGLLAYEKDLDDYSSILIKALADRFAEAFAEYLHKEVRT
KHWGYAANEILSSEELINETYKVEEKIGVKLTESIAMWPAASVSGYYFGNSEARYFGLGK
IKEDQVIDFASRKDIAIEVATNLQFIDVTTSREEYVYLDRSGLLDKKLTRMRPGTVGICA
SIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNVMALRGDAMREQPYFEPTKGGH
PFAVDLVSQIQNLNCGKYLHEVIETDDYLKRLKEKVDAGADYVVTQMFFDNKKYFEFVAA
AKEMGINVPIIPGIKPLAVKRHLQLLPQVFRIDLPQDLIDAVDDCENNKAVRQVGVEWAI
QQSKELKEAGVPVLHYYSMGKSDNIRTIASKLF
>Q1QR87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)|TrEMBL
MTDASAPVHNGPAAQKRPAISFEFFPPKTEEMERNLWDTITRLTPLAPNFVSVTYGAGGS
TRERTHSTIARILSETELRPAAHLTCVGAARGEIDEIVSRYHDIGVRHIVALRGDPPGGI
GTAYSTHPDGYRSSADLVAGIKRQYGDIEVSVSAYPEKHPESRDIDADIDVLKAKVDAGA
ARAITQVFFDNDLYLRYLDRVRARGIFIPIVPGIMPMHNFRQARAFVTKAGTTVPSWLAE
KFEGLDDDPETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFTVCHLLGIRPDAA
QKAA
>A0A081RFA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium chlorophenolicum|TrEMBL
MKLAYVDQHAPTVDLIQSFSLEMTAKDIESLTDAAPLIPAGTPISVTYLPGEEMPARVAA
AQAVKNLGFVPVPHISARRVLSRDDLQQFLAMLDEHVGIERAFVIAGDPASPMGPYEDAL
AIIRDGLLPTVGVRKVGISGYPEGHPDIDKPKLAKAMHDKIAALSDQGLEAEIMTQFAFD
ADAILVWLERIRQEGVTIPVRVGVPGPASVKKLVRFAARCGVGASAKVMLKYGTSITKLL
STAGPEKLIEELADRIDPSVHGDVLLHFYPFGAFVDTAQFIANHYGTAKA
>A0A3R9MQQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPNVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1S1R6A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. EUN1h|TrEMBL
MTSLPVEQAGRLATLLHDVSLEMTGKDIEELDLARESIPTGTCINVTFLGNEDLQMRLAA
ARAVKAYGFVPVPHISARRLESRASLEVFLAALQADGTGEHVFVVGGDPSVPHGPYADAL
SVIQSGLLEQYGVRRASVAGYPEGHPDIPDRILWPALRDKHASLAERGLAGDVITQFGFD
VDSVLTWTEALRERGVDAPVRIGVPGPAGVRRLLRYAARFGVGTSASIAKKYGLSLTNLM
GTAGPDRFLHTLATDYDPRRHGEVKLHFYTFGGLRTTSEWIDHLRKEG
>A0A235EGL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax kalamii|TrEMBL
MNAANAQGTGFPVSFEFFPPKTPEGADKLRVARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVGAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLKAYVAKVQAGADSAITQYFYNSD
AYFRFVEDTQRLGADVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A2W4D4G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium tumorigenes|TrEMBL
MTSTPDTGRSDLSISFEFFPPKTPDMEGQLWAAITELTEWQPEFVSVTYGAGGSTKAPTL
NTVRRMIAETPLPTASHLTCVSATREDTHRVVDELRAAGVRHFVALRGDPPGGMGTAYQP
HPGGYENAAALVAGLRDIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDVFETYMERVRAAGIAIPVLPGIMPIQNLTQLKRFAGMCGTSIPSYLDDRFAGLDD
KPEERAKVAADVASEQIEDLVRRGHREFHLYTMNRAPLVGAVLDRLGFKRTKIVEAAGAA
A
>A0A2P8BKV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CS149|TrEMBL
MALGTASTRTDHARTVREMLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>B1HA75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei S13|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A3P3ZIE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania braziliensis MHOM/BR/75/M2904|TrEMBL
MVSTLDAIRQAVENSCYFVSSECVVPTTEIGAVALYDIVERLPALDPLFCSITWGNDGRT
AETFIEVASVCQSLLSVNFQVNLTGYTSKLEVLKWLRLLKAKGVRNLLVRRSAPTAGSTT
TSCNGDIGVGPRTTAAGSHGTPREEVNATTSTSLAPITTVSSSFSVSAFPHAVGFV
>A0A7W6D692|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium azooxidifex|TrEMBL
MTIATNSDPRYAGRSRGPKLSFEFFPPRSGEAEQLLGETIEALAAYAPDFVSVTYGAGGS
TRGPTLATVSRILRETSLPAAAHLTCVGATKAEVAAVVDEFRAVGVRHFVALRGDPAGGI
DAAYEPSPDGYANAAELVAGLKAIADFEISVSAYPEKHPESRDVAADIDILKRKVDAGAT
RALTQFFFDNDHYARYLDRVRAAGIEIPIVPGILPVHNLGQVQKFAGLCGASVPQWIADR
FEPLADRPEARAAVAIELAARQVDGLIALGVEEFHFYTMNRSALVSAVLDRVGIERDDAG
KQGRAEGAAA
>A0A5C8TAH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. WL64|TrEMBL
MRRPTHRASRDGYHPIRVSIEFFPPKTDEMEKVLWSSIERLAPLQPKFVSVTYGAGGSTR
ERTHNTVARMIRETTLKPAAHLTCVDASREEIDAVVQSYWDVGVRHIVALRGDPADGVGH
AYRPHPEGYATTAELVAGIKRIGDFKVSVSAYPEKHPEAATLDADIDALKAKVDAGADQA
ITQFFFENEVYLRYLEKVRAVGITIPIIPGILTVQNFKQSANFARRTGASVPYWLAARFE
GLDNDVETRRLVAAAVAAEQVLDLVDEGVQDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AEKAAA
>A0A255S771|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. P3-120|TrEMBL
MTVTEYIKQNNGERGFSFEVLPPLKGNGTEALFRTIDKLAVFNPGFINITTHHSEYIYRE
LKNGQFERLRVRRRPGTVAIAAAIQQRYNIPVVPHVICSGMTIEDIEYELLDLQFLGIQN
LMLLRGDKAKEDSRFTPTPGGHAHTTDLIEQVVRFNNGTFADGTTIKHPGTKFEFGVASY
PEKHEEAPNLERDMEYLKQKQELGAQYAVTQLFYDNEKYFDFVEKARQMGITIPIIPGIK
PMAKLSQLTVVPKTFHCDIPEALAKEIVKCKTDEQARQLGIEWTTAQCQELYAHGIQNIH
FYTVSAVDSVVEITKRLL
>A0A1G7GQQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pricia antarctica|TrEMBL
MKVTDHIKNAKGETLFSFEIIPPVKGHRIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIRHKYDVDTVPHLLCGGFSKEETEYVLVDCHYLGIDNV
MALRGDAMKDEKYFKPAEGGHEYATGLVKQLHDLNCGTYLHDTVETEHCADFCIGVAGYP
EKHLEAPSLQSDLKRLKEKVDAGAHYVVTQMFFDNQKYFEFVDAAKAMGINVPIIPGIKP
IAVKRHLQLLPQVFRIDIPQDLIDAVDACKDNKAVRQVGVEWCIEQSKELKAAGVPVLHY
YSMGKSDNIKAIAEKVF
>A0A3P7PS73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dracunculus medinensis|TrEMBL
MEPIRHNDDAVRKFGIHQAVHLCRELLNKGLTTSIHLYTLNRESASREILQELGLWIKKP
MRTLPWKSFGCNHPVRYKETVRPIFWSTRPNSYVFRTQDWDDFPNGRWGNSSSPAFNDLA
DYYLFYLKGHLSKEDQLKMYGELKSIVDVQNIFVSFISQQPNQNGIKVTRLPWNEQEIGT
QPETSLIKEQLIWCNKHGILTINSQPAVNGASSTDPLVGWGKPGGYCYQKAYLEFFTSQK
NTESLRQLLPLYPRLSCQIINHNATIDWTNGESTMPIAVTWGVFPGSEIAQPTVVDPLSF
RVWKDEAFETWNNW
>A0A368GRA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylostoma caninum|TrEMBL
MLSLHEFLCAMSKSSACSKVVEKREDRWVGHGNKYVPLHERINRRIKDKTPFFSLEFFPP
KTANGVANFFTSQHEQRDLFIFHRCRMPGLLPSRHNVTHDMCTIFKRANDKTPGTDTDGI
PIYKYRALDMIRWIREEFGDYFTIACSGYPLGHPESPSYKADLLYLKSKCDAGAQFIVTQ
LFFEAEVFEQFVRDCREMGITVPIIPGIMPIMGYDSIRRIATLSQLTIPESILSDLEPIK
HDDDAVRKYGTIKAIEMCRRILSNGSAPSIHLYTMNREGACR
>A0A4V3UX87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium ML5|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRQIAQDYWQSGIRHIVALRGD
LPAGGGKPDMYATDLVHLLKEVGDFDISVAAYPEVHPEAKNAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPHWMNSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEVAVPV
RA
>A0A7W7MGG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes lobatus|TrEMBL
MSLGLPSRLPGAPSVGELIRGPAPTFSFEFFPPKTPAGEQLLWQAIRELESLRPSFVSIT
YGAGGTTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRNVIGRLAGAGISNILAVRG
DPPGDPMGEWVRHPDGILYAEDLVRLIRAAGDFTVGVAAFPYKHPRSADVETDTQHFVRK
CRAGADFAITQMFFDAEDYLRLRDRVVASGSDTPIVPGVMPVTRMATIERSAQLSGAPFP
PALLERFERVAGDEEAVRALGIETCVDMCARLLDEGVPGIHFITLNRSTATREVWQQLAP
AEVATAA
>A0A8J6R7V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nodosilinea sp. FACHB-131|TrEMBL
MGYRLRTAAQADQFLVTAEVMPPKGGNPEHMLAMGQMLKGRVHAVNVTDGSRAVMRMSSW
AAALLLQQQGIEAVCQMACRDRNRIALQADLMGAHALGLRNVLALTGDPVKAGDHPEARS
VFDLESVRLLKLLEKLNFGLDSNDKPLTDGALDLFAGAAIDPQSTSWSGLQRRFETKVKA
GAQFFQSQLITDFDRLAKFMDQVASGYNRPVLAGIFLLKSAKNANFINRNVPGVNIPQTI
VDRLTAASDPLQEGVQIAAEQVQAARQVCQGVHLMAVRREDLIPQILDQGGVAPVDAALA
ER
>A0A2E9D1X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MTQKNTNDEPDAVQVSFEFFPPKTEKSEATLWQTVERLAPLDPRFVSVTYGADGSTRDRT
HRIVSRINAETTLTGAPHLTCVDATTAEVDEIARSYWEDGVRHIVALRGDPPQGQETYEP
YPGGYEYAADLVTGLRDVADFDISVAAYPEVHPEAQSPIADLDNLKRKLDAGANRAITQF
FFDADVYLRFRDLTVAAGIDAPIVPGILPISNFASLLKFAGSCGASVPGWLHERFEGLDD
DPETRQMISANVAIDLVHKLQREGINEFHFYTLNRAELTYAICFALGLRPDVVTANG
>A0A6B8KKE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystis heyeri|TrEMBL
MTAEPRHPLSSKGEFVISYEFFPPKTPQMETQLWETIKRLEPLCPRFVSVTYGAGGSTRE
RTHAIVARIARETTMKPAAHLTCVSATREEIDKVIRDYWDAGVRHIVALRGDPPGGVGTP
FMPNPLGYPTSSHLVRGIRAIGDFEISVSTYPEGHPESSSIDNDIDALKAKIDAGATRAI
TQFFFENDVYFRFLDRARARGITIPIVPGIMPVRNFRQVAGFAAKAGASVPQWLADRFDG
LENDPETHALVAATTTAEQVMDLVKAGVNEFHFYTNNRADLVFGICHLLGVRPARQKASA
>A0A023CJ66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parageobacillus genomosp. 1|TrEMBL
MEPIVQINLRDRNRMGIQSDLMGLAALGIKNITILGGYPAKIGTEPNAKEVYDMETMELV
RYVRRFVDEGKLFDNTVMEEAPQMAIGVVENIAGKPVKELIDRLEAKIDAGANFVRTQLV
FDIELLEEWMEEARRRGLHERSYIMASILPLRDADHVDAVLKIPGIAIPENIIKRIKEAN
SPDEGTKMVVELIHKLRNIDGIRGIHIRPLGGMDHFVSKIVREAGLMNRKLEKVTEYVS
>L5KGS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pteropus alecto|TrEMBL
MDYPKPQVLPARHRCPSLGKQAWEAGSMRFSVPPSIRNSAMVNEPGGHGSLNLRSEGSGS
GGESSKDSSRCSTPGLDPERHERLKEKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRFD
RMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITGH
LHKAKRLGLKNILALRGDPIGDQWEEEEGGFCHAADLVKHIRSEFGDYFDICVAGYPTGH
PDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQG
YHSLRQLVKLSKLEVPQQMKDVIEPIKDNDAAIRNYGIEQAVSLCQKLLASGLVPGLHFY
TLNREMATTEVLKRLGMWTEDPRRLLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELASEESVFEVFVRYLSG
EPNQKGCKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNVNGLPSSDPVVGWG
PSGGYVFQKAYLEFFASRETVHALLQVLRKYALRVNYHIVDVKGENITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSRIIIQYIHDNYFLVNL
VDNDFPLDNCLWQVLEDTFELLNTPSSDERQPEAP
>A0A5S4ZN69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfallas thermosapovorans DSM 6562|TrEMBL
MKLCDLFEKGKFVVTGEAAPPKGTNTAKMLSEAAPLKDMVDAVNITDNQSAVVKMGSLAA
SRCLKDNGIEPVYQLTCRDRNRLAIQSDLLSAAALGIENVLCLTGDHVSLGDHPHAKAVY
DLDSVQLLKIASGLNHGKDSSGNELDGSTDFCLGAVVSPCTEPVEMQVIKLEKKIEAGAC
FIQTQAVYDTRLLEDFMNRLARRNITVPVMVGIVFIKSASMANYMNKNVAGIEVPETIIK
EFENTPGDGLKAKSLEITIGLVNAYKDMCQGIHFMPLGWTDMVPEVLKSTGLRP
>A0A0R1M6Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus capillatus DSM 19910|TrEMBL
MTELNSLHIHQLLALRGDIIPEIPRKKDFEYASSLIKFIHEQNLDFKILGACYPEIHPES
PNLVSDIHYLKQKVDAGCDQLITQLFFDNDKFFTFKENCALADINVPIIAGIMPITTRKQ
ALRLIKTTSAHLPQKFLAIFDKYEHDPASLRTAGLAYAVDQIVDLLTRGVEGIHLYTMNH
AKTAIDIQNTIGSLFKTNQQ
>A0A2G0CH60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lewinella marina|TrEMBL
MRVTEHFERANGQTLISFEVLPPLKGGSMQAIFDTLDPLMEFDPPFIDVTYHREEYVYKK
RPSGYYEKTAIRKRPGTVGICAAIMHRYGVDAVPHLLCGGFTKQDTENALIDLAFLDVQN
VLALRGDARKFEGRFVPEKEGHHYACELVGQIVDMNNGHYLDELIKDEHASKTNFCIGVA
GYPEKHFEAANLEHDLRYVKAKVEAGADYIVTQMFFDNQKYFDYVDACRKVGINVPIVPG
LKPVTKLYQLNSLPRMFHIDLPDDLVTAMTKAKDAEARVQVGIEWCTAQSKELKARGVPC
LHYYTMGDSSTIRAIAEQVA
>A0A0K2D954|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chelatococcus sp. CO-6|TrEMBL
MSHAPFRPSRRGACPVRVSFEFFPPKTPEMEATLWASIERLAPLGPHFVSVTYGAGGSTR
ERTHSTVKRLVEETPLAPAAHLTCVSATRPEVDEVVRAYWAAGVRHIVALRGDPAEGIGA
AYTPHPGGYDGSPELVAGIRAVADFEVSVSAYPEKHPESVSIDADIELLKRKVDAGATRA
ITQFFFDNDVYFRYLDKVRARGIDIPIVPGILPVQNFKQAANFAARAGASIPAWLAGRFD
GLDQDVETRRLIAAAVAAEQVIDLVDRGVTDLHFYTMNRADLVYAICHLLGLRAGTAVAE
PVAAAAVA
>G9ZTS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus parafarraginis F0439|TrEMBL
MPCTNKKQIERIASITGVPLPKKFVAILDRYADSKEAMRDAGIAFAVDQIIDLVSEGVDG
IHLYTMNRADIAERIWDATKSVFAAANSKKQQRASSH
>A0A6G3CQM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5614|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PESLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A417RKV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM05-9BH|TrEMBL
MLYQGNIRDYLSKQPLLFDGAMGTYLADKYIQFGGESCEKWNLRYPERIKQIHKEYIDAG
AVAIKTNTFAANAGDHFTAEEVGKVIAAGTQIAREAIEESAGEQILFGDIGPVVIGDEND
AAERYRLPVDCFLEQGVRHFLFETLDNIEGLDEITEYIKQKQPEAFIIVSFAVSPEGLTR
SGCYGRSLYQKMMKVSSIDALGFNCISGPKHLLDLMYKLSREKNTKYISIMPNAGYPAVL
DNRTYYEAHHYYYAKEMYQIAKQGASIIGGCCGTDPSFISEIAKTLQQSPLPGRKTYSAD
GSGRSVHSVVENRQTEQSIPVANDGQEVKNYAGKDNLCNTFAAKLACGEKVLVVELDPPV
TPEIDFFMEGAVKYQQAGVDAIDIADCPVAKARIDSSILACKVMRELGLTAIPHMTCRDR
NINATKALLLGLNVEGVNNVLTVTGDPVPAAERGLVKTMFSYNSAVLANHIRTLNEQIFQ
NNPFMISGALNVNAVNFDSQIIHAKRKISQGIDVLFTQPVLTERALNNLKRAREELDVKI
LGGIMPVVSYRNACFMNSEMAGIDVDPRIIEMYQDKDRAQGEELAEQISAQVAQEIAPYV
DGFYLITPFKRVELILRIIKQIRGLLDR
>A0A0L0QUN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Virgibacillus pantothenticus|TrEMBL
MSLLQQLQDQILIADGAMGTMLYSYGIDQSFEQLNITHPDQVQQVHEAYIHAGATVIQTN
TYGANYIKLARYGLEEQVKKINQKAVQIAKQARQKGVYVLGSIGGIHGVQALNETKEEIK
RSFREQLYCLLLEGIDGLILETYYNLDELTMVLEIAREETEIPIIANVSMHVPGVLENGT
PLAEALQQLESLGADLVGVNCRFGPSQIITSLQSVPLPKKAFLAAYPNASLPAYRDGVLY
YKNEPAYFKQCAGQLREQGVRLLGGCCGTTPDHIKALAEGLKDTDPITEKVVEIPQRERV
ILKRKRKEKSLAELAKERHTIIVELDAPKHLDMTEYYQGIRALKKAGIDAVTLADNSLAT
PRICNVAVATIIKEQGIRPLVHLSCRDRNLIGLQSHLMGLDILGIHEILAITGDPTKIGS
FPGATSVFDVNSFKLIELIKRGNKGMSFSGDSLREHTSFTVGAAFNPNVNHVEKSVARLE
RKIASGADYIMTQPVYSKEKIIALKQATSHIETPIFIGIMPLTSTKNAEFLHHEVPGIKL
TDEVRSRMKAAKGNREQSTKESIAISKELLDTAFEHFHGIYLITPFMRYDMIVELVNYIH
QKTNAMRAQASLSSY
>A0A855Y693|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. ARC270|TrEMBL
MSFFHANQREALNQSLAELNGRINVSFEFFPPRSGEMEETLWRSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRAIAQDYWHNGIRHIVALRGD
LPEGGGRPEMYGSDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMNAMFA
GLDEDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAVAA
>A0A841ML29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus iocasae|TrEMBL
MKITEHLKNANETLFSFEILPPLKGQSLKELLEGIAPLMEFKPPFVDVTYHREEYIYKKH
PNGLLEKISTKKRPGTVGICAAIMNRFQIDAVPHLLCGGFTKEETENALIDLNFIGVENV
LALRGDAPKTEGKFIPETDGHHFASELVEQIVRMNNGKYLHEETETSFHTDFCIGVAGYP
EKHFEAPSMKFDLKRLKEKVDRGAEYIVTQMFFDNQKYFEFVKEVRAAGITVPIIPGIKP
ITTIGQITMLPRTFFLDLPDALMDELEKCKTNSEVREVGIEWSIQQCKELIQAQVPSLHF
YTMSKAGTTYAIAKEVF
>L7E2S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa TAIHU98|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPVDN
>A0A2G3LHF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. BJB426|TrEMBL
MVGPLMHPAQPWPAGNITDAYSLEASTKDIAALSAAAPRILPGSTISIPYLAREDDDTRL
TAARAVRKLGFEPMPHLSARRIVSLAGLESFIQRAVAEAGVERCFVIAGDPSTPMGPFSD
SASLIDTGVFERAGMKVIGVGGHPEGHPVMSKAEQWEVLERKCHSIEMRGMAPLIVTQFA
FDADIVLTWLQALRARGINHPVRVGVPGPASIAVLARYAAVCGVGACASMLSKYGISIGK
LFGTAGPDLFVERLAAGLTAAHGKVSLHFFPFGGIAQSVKWVEQYRSSTAPAP
>A0A3E4UKE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides stercoris|TrEMBL
MRVIDLINCNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEKNGYHHAVELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTNEILKCKNDAEAQQVGIEWCVQQCKELMKYHIPSIHF
YSIGAVDSIKEVAKQIY
>W7EC15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bipolaris victoriae FI3|TrEMBL
MHISQKLAQAKREGKPTFSFEFFPPKTAQGVQNLYDRMDRMHSFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALREAYQAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDDVDELIDHLKEKVDAGGSF
IVTQMFYDTDLFLEWVRKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTKCHIPDDWTKAL
EPVKNDDVEVREVGKTLVADMCRRLIDAGITHLHFYTMNLAQATRMVLEELELLPDVESP
LEKPLPWRPSLALNRREENVRPIFWRNRQRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPLTIRDFSNLFVRYMEGKLESLPWSEQPITAEASSIRDDLID
LNRRGFLTINSQPAVNGVKSSDPVFGWGPRNGYVYQKSYLEVFVSPEHIAEIITRLERDP
EFTYYAVNKNGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGISPSRYVIQDVIDTWYLLNIVHNDFHATRGIFPIFNGLEVKDMDKPLHTPSADL
PNANGSENVNEANGVNGTSGTHKEESPSLIDVAKAAAIEVTNGMKSLAVSN
>A0A235AYG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. N4311|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWDAVSKLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGNFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGINEFHLYTMNRAPLVSAVLDNLGFSRRAAKSAGAAA
>A0A4R2KJX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum euryhalinum|TrEMBL
MSAPRVSFEFFPPQSLEGSFRLWETVQALAPLKPQFVSVTYGAGGTTRKLTHEAVETIHN
HYGVNVAAHLTCVDATRAETMEIVDAYAKAGVTEIVALRGDPPKGQGGFTPHPEGFANSC
ELIEALASRAAFTIRVGAYPDPHPESQGVGHDIRWLKRKFEAGADSAITQFFFEAETFFR
FRDECDAAGIDGSKIIPGILPIEKWAGVRRFAERCGARIPAWIDEAFEKAVRDDREELLG
KALATELCTALMEGGVQDFHFYTLNKPHLTRDICHALGVQTPAHLEKVA
>W7E9G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bipolaris victoriae FI3|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDEALEQAQVLGIRNILALRGDAPRSEE
YRDEDTPPEQDSNKDFTWAVDLVTYIRKQYGDYFCIGVAAYPEGHSDQSHPEHQDPVADL
PYLVEKTKAGADFIMTQLFYDVEAYDKYEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHAKLPTDILARLDAVKSDDELVKQVGVQIMNEIVEHIKARPDTCRRGFHFYTLNL
EKAVSHILEDTKLIPSTLIDDDEVIVETTPAINLEPPPNGIMPHRRRSSAVNSGPRNRVI
VSHVSAARSSNPSYEATEEEAGIPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKNDISTLFRRHIEGDLEAIPWSEQGLSP
ETLTISKQLLALNAKGWWTVASQPAVNGIKSTDPVFGWGPKNGYVFQKPFVEFFIPASEF
AVLQPKLDAHDQITYFAGNAAGDFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIWREWQRIYPPRSASSTLLGELRRDYWLVNVIWGDFVNGEGLWEFLLE
>A0A383A373|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MSIPETNNQAYTYRPGELLPELEGHISRGRFERVLRNGDFAVTAELAPPDSTDRNEVFEQ
AALFDGFVDAINATDGSGANCHMSSVVVCALLSYIGYSPIMQISCRDKNRIAIQGDLLGA
GALSICNVLALTGDDVS
>A0A382JRS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MTSVVERRSQNPDSVFFACDFSPPRGADPKLLSPALSLTADFISVAYNPGRSVRINSVLA
ADWIQQKTQSDVIFSLSTRDINKIGLQSLLLGAQLAGLKNVVVVKGDNLSSSELSMTKSV
HD
>A0A382JCG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MRLIRDILREHKEAGKTAISCEFFPAKTPAGETALLEKIVPRLKAVNPAFFSVTYGAGGG
TRDKTLDIVETIQRDQNVPAMAHLTCVGSTREDIDGFLDEASNRNICNILALRGDPPEGQ
EQFVKPEGGFEYSYQLVEYLHGSNELSIGVAGFPEGHIACTEGKEIDWQRLKGKVDCGAD
FVITQLFFDNSDFFEFRDSLRSQGMSKP
>A0A838KPJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MRNKARTRTAVKEALAAARYEVLPTAKIEAEVVRVVPRDVTITVTASVTKGISVTLDLTE
RLIAAGYTVVPHLAARMISGRAELEQIVTRLTGLGVSNVFCPAGDADPPVGDYAGSLAML
EHLTRMGRPFAEVGITGYPESHPAVEDDITIQSMWDKRVHATYVVSNLCFDPDTIHNWIR
RMRRRGIDLPLLVGLPGPVERAKLVSMATKIGVGQSVRFLKSHASTFARIAAPGGFSPER
FLQRSAAYLGDPSLHVDGLHLFTFNQIAETEAWRQQQLRS
>A0A382H6U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
VRIRDKIKRPRRPVVVYEILPPREKDGTLNSYAEIISSLLSQTHIDAINIPEVRDESMRG
ARPVKNKTRAEPREFGKLLQDIVGIEAIVNRVVVHQPVKEEMNWIEETYKIYEIENLIVV
GGESSKINYIGPTVNSALRAINSRIDTNGCDILCGGITIPSRLKESKSLINKSKNGSEFF
TTQVLYDSSKIKRLMSHYQARCNKMNTFPRRLLLSFAPVSSQKNIEFLKWLGVEIPDKTE
SYLKGHPASMIERSLNVAVEVLNETLDHIKKNDLTVPIGLNVEHIMSYNFQASVEML
>A0A7Z2V436|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. gcc21|TrEMBL
MSQLINGAPVSFEFFPTKTDAGHEKLIAAAHVMAAEKPEFFSVTYGAGGSTRDRTVNTVL
QLDQEVKIPTAPHLSCVGDSKEDLRSLLNQYREAGIKRIVALRGDLPSGMGRASGELRYA
NELVEFIRQETGNHFTIEVAAYPEAHPQAKHFEADLENFIRKARAGADSAITQYFFNADC
YFYFVERVRKAGVDIPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSASIA
AFGTEVITHMCERLLDGGAPGLHFYTLNQAEPSLAVWRNLKRS
>A0A7Y5WG35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MLSSARYEVLPTGTVEDKVLEHVPLDRTVTVTASPAKGLEATLELTERLAKHGYHTVPHL
AARMVSGRSELAEVSERLVAAGVRTVFVPGGDQDPPAGDYLSALDLLEDLTALGRPVPEV
GITGYPDSHPTISDDLTVQSMWDKRRHATHVVSNLNFDPDTIKDWVGRMRARGITMPLLL
GVPGPIDRAKLLSMATKIGVGDSTRFLAKHKGTMARLAAPGGFTGERFLEKCAPALSRPE
ALVTGIHVYTFNQIAETEAWRRDFLARVSPVRAD
>A0A381TSS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MESSMKFKDSLYDNFSFSADLNLAVAGSVGDLLDQSRILSKSVDGIHVSDGPNAGVHFPA
LATAQLLLENDIDPILQISCRDKDRLTLEIEIRGALALGVTSVLLVRGESAGISGTSDRI
VKVSTTELIQMARRIEEGAEQANLSVGTIATVFKPATDWQPQALLKKTHAGANFIRTQLC
FDADKLKLYMPNLVRAKVTWKAPIIVNLAVLPSAKAAKWLSENLRGSLIPKTVIKRMEQA
DDPEAEGVQVAAELMAEFDTIPGISGVCLMTPGLPELIPEAVNASGLRQG
>A0A2E6ESS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MDDLRSVLEGRALLSDGAMGTEIYRRGVYINRCYDALNLSDPELIAGIHSDYAEAGADLL
TTNTYGAHRMRLSRFGLEAEQGGIISSGVRLARAAAAGRCYVAGSMGPLPLLLRPAGPVS
KEEALATYREQAEIMLEEGVDLIVLETFRQLSMLEHAVAAVRGLSTDIPLVASFAFKPQR
HYFVGATPEDVAAAVSSWDVDLLGTNCVIGPQAMLDVVERLREATEKPILAMPNAGQAEM
VEGRTLYLASPEYMGEYTRRLFQAGAQIVGGCCGTTPEMVRQMRSFLNSAEPTVAPARIR
RIEPVQHSSVEVTPIEERSRWGERIGGEFTVSVELDAPRGLDASKSIEGARLLASHGVQA
VNIADGPRATARMSALALALQVREQVDIDVIVHYCCRDRNLLGMQMDLLGAHSLGVRNLL
CVTGDPPKMGNYPDATGVFDLDSVELVRAVHNLNRGVDFGGDSMPEATDFVIGCGCNPGH
VPLEKEVAKFRRKLEAGAEFVFSQPLYDPTVLERFLAAIEDFPEVPFLVGILPLASAKNA
EFLHNEVPGMQIPAVTRARMERAGSRDEQRAEGIRIAGEALRLARSYPRVTGAYIFPPFG
RYLSVPEVFEASEQRVEV
>A0A381SGZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MGFELIPLKNIANQAAHLPHGATVSVTCSPAGTIDDTLDLCATFTAAGHTTVPHVAARMV
DGEDHVDRIVARLTAQGIRRVFVIGGDAEQRGPFADAAGFLRSFLDRRPPVDAVGIGAYP
DGHPSIPDRVLVEALAEKQAMIADAGLEGYLTTQMCFDPGTIADWLAARRAAGITLPCHL
GVPGAVDPARLLSISLRLGVGASARYLKKNRLSVLRLLSPRRYDPNKVVAPLSAVADQLG
VVGIHCFTFNSVEATEAWRQKSLARLA
>A0A7Y0Q012|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassotalea sp. Y01|TrEMBL
MNAKARQLDLLNRTVRDLDRDLNVSFEFFPPNSEQMETTLWNSVERLEPLNPSFVSVTYG
AGSGTRDRTHGVIKRIQRDTSLVAAPHLTCIDASKQELIDIAKDYWQSGVRHIVALRGDL
PNSSEKPNMYASDLVEVLKGVADFEISVAAYPETHPESPNAQFDLVNLKRKIDAGATRAI
SQFFFDIDAYLRFRDRCVAVGIDVEIVPGILPVSNFATLKRFAGLTNVHVPDWMGKLYEG
LDDDPTTRNMVGANIAMEQVKILRSEGVNDFHFYTLNRSELTYAICHTLGIRPQQG
>A0A2E3IVJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MHITDIINKGRPTFSFEFFPPKSERASESLFETIKDLESLAPSYVSITYGAGGTTRERTH
DLVEKILEKTTLIPIPHLTCVQHTEEEISNILKRYSDKGISNILALRGDNPKGDAQYDRS
KDSFCFARDLVEFIRNFDNSTLDKKSKSFGIGVAGFPEGHPETPNRIKEMDHLKAKVDSG
ADYICTQLFFDNHDFFDFRDRCELAGINIPIIAGIMPVTSISGMQRMADLAAGSRFPAKL
LKSIDRCNLDSSAVERVGIQYATEQCSDLLNNGVDGIHFYTLNKSKSTRGVFEALGINKT
>A0A2H0HP53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium CG17_big_fil_post_rev_8_21_14_2_50_64_11|TrEMBL
MAAXXFEFFPPKTDEQREQLDKTAARLAKHQPEYVSVTFGAGGSTLSYTPETVRNLHQRH
GLDATPHISCVGGSREEIRSLLVQYRAQGCKRLVALRGDMPSGMARAGDFRYASELVGFI
RAEHGDTFELLVGCYPETHPQAEHAAADMAHFKLKVDAGADAAITQYFYNADAYFHFVDG
ARRHGIDIPILPGIMPIANFSQLRRFSEGCGAEIPRWVAKRMASFGDDRDAIRAFASDLV
AGMCQRLLNGGAPGLHFYTLNQARPTLAVLERLR
>A0A432NU96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium anhuiense|TrEMBL
MALKNEARGRNIRISFEFFPPKSEEMEGQLWHTVSQLQDWDADFVSVTYGAGGTTKAPTL
STVTRFLSQTPFATASHLTCVGATKEETHQVVDTFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLREIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGANRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGVSRRETKSAGAAA
>A0A2E3G6U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MIYLELVPRNLEQLCTDSKLYLDSFSDLTGINIPDIKRLPIRSSKAANALLEHEMTVIPH
IRTQDASLDDHLSMISRLYQHGLRHVLLISGDPDDTTMSYDVTPPILTKHLKQSFSDLII
YCGIDPYRQSFDEECRYTYEKLEAGADGLFSQPFFDVSLLETFLKSYSSTQFFCGISPVT
SQRSLEYWQTINRVCFPQSFDLSFAYNVSLAKDLLACSQHYNQHAYLMPIRTPVKEYLES
VFT
>A0A3E2CSB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium NR020|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQESAGVFEHASDL
VYYIRSKHPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNADCLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A1Y4CJL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera sp. An286|TrEMBL
MRTNELFAKKTVFSFEVFPPKPDTPIETIYAALDELSQLYPDFISVTCGASGSGSGGNRT
VEVASAIKHTYGCETAAHMPCIYLTEDDALRTLDELKKAGIENILALRGDETPGRERAHV
FEHASDLVAFIKRNAPEFNVIGACYPEGHTEAQTMAADIRNLKTKVDAGASELISQLFFD
NATFYRFLERCEIAGISVPIEAGIMPVTNKKQIERMVSLCGATLPVKFQRAIAKYGDNAE
AMRDIGIAYAIDQIADLLANGVDGIHVYTMNNPYIAKKITEAVKNLL
>A0A109BP06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. WDL1|TrEMBL
MRLPLSFEFFPPKTPEGAVKLRAVRQQLYARRPEFCSVTYGAGGSTHEGTFGTVREILGE
GVDAACHFSCIGATRTTVREQLKELKAMGVKRLVALRGDLPSGYGMGGEFHYASDLVGFI
REETGRDFHIEVACYPEVHPQARSPEADLRAFAAKVSAGADAAITQYFFSPEAYFRFVEE
ARGLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TELCERLASGGAPAMHFYTMNQSVATLALLDRLGWEG
>A0A3D4WEM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp|TrEMBL
MTKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRGRTLDIVQALCA
RGDTDIAPHMSCIGDDKSQIAELLDLYKSLGITRLVALRGDLPSGQVSMGELPFALDLVK
FIREYSGDHFRIEVAAYPEMHPQARSFEFDVDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTVAQPLVAGIMPITNSSNLVRFADSCGADIPRYVRKRLADFGDDRKAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKIEPNKRLVEALGLTA
>A0A1F7S0H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Schekmanbacteria bacterium RBG_16_38_10|TrEMBL
MSLKNILEKGKFVITAEIEPPKGTDVSKFFETSESLRGKVDGLNITDQQGAVMRLGSLAS
CHLLIEKGFEVIFQITCRDRNCIALQSDLLSASVLGIENVLILTGDHPQLGDHPDSKPVF
DLDSVQLLQVAKTLEGGYDFSGNKLKKEPKFFLGAATNPGADPLEPEIIKAEKKVKAGAA
FFQTQAIYDPVKFKNFIDKIKHLNIFIMAGIVLLKSAKMARYMNENVAGINVPEELIKRM
ETASDAKKECIEISVSLIKEIKNFCHGIHFMALGWEDLIPEIISKVNLPNE
>E9T6J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus hoagii ATCC 33707|TrEMBL
MTFDAVRGRNSAGFVTQTPSIVDRIRSSEASKSGRIPFSVEFSPPRDEAAEARLWRAVRE
FERLGPAFVSMTYGAGGSTRDRTVRVTGQLADDTTLLPVAHLTAVGHSIDELRAMCGAYA
DRGISNILVLRGDPPGDPLGDWVKHPDGVEYAEELVRLVRDMGDFHVGVASFPEGHYRAP
DLDHDTKYLVQKLRAGAEYSITQMFFDVEDYLRLRDRVVAYDREQGEKPIIPEIMPITSL
RSARRSLELSGSSLPPALEERLTRAAGDGPDENRAAVREIGIEVATEMSERLIAEGAPCL
HFITLNFARATGEVLANLGMSASASV
>A0A1S1R7X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. Cc1.17|TrEMBL
MRESTAGHGHPARDFELICEIEPPTRPDLTHARHQIGVLSPVTDAFLIPDNHIGRATVSS
IAVAHEVQTMGGRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVHGDKPTAGNRTSDL
TVRAMMDEARAAGEDPVFADMPAFRVGAAAGLRPLPAWKRAADFLFVQVSYSVDALLRWR
DAHPVELPVYAGVMVLASAGMARRLAATIPDIDIPDDLVQAVERDRAAGVDAACDQVLQL
RESGAFAGVHLVPVSRYRQVAARLEDLL
>A0A2N8E3E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FW215-R4|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVTEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A2E0IZ37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinisphaera sp|TrEMBL
MTHISQNSFSIEFFPPKGPKGAARLDKARAELATLGPDFFSVTFGAGGTTRSGTLETVQX
SMESTGIAAAPHLSCIEGTYESIXELLDNYKSAGVDRIVALRGDLPEGMDKPGVFSYANE
LVAYIKERHGDDFHLXVGCYPEYHPQAPTPADDVDNFVRKVNAGADSAMTQYFYNADAYF
NFMDEVTARGVDIPIVPGIMPITDFGQVSRFSAMCGADIPRWIRQKMEGYGDDKASVQAF
GHEVVTRLCEQLLAGGAPGLHFYSLNKAAPTVALWRDLGLPVPQGRASQTG
>A0A7C4AG41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fundidesulfovibrio putealis|TrEMBL
MRISDLLAQGKRFVSLEFFPPKEKDAWPAFFGEVERLAVLNPLFVSVTYGAGGSTQVNTL
ELVARLKRDHGLNPMAHLTCVGASEDSLRGFLDSLGQAGVDNVLALRGDPPQGQPDFKPE
NAAFQHASDLAGFIHAAYPGMCIGVAGYPEKHPQAESLEQDIDYLLLKQQRGGAFAITQL
FFNNDHYFAFVERCRARGITIPILPGVLPILNLASIKRILSLCGASIPPDYLARLEAAND
GGGAQAVRDLGVAFAHDQCRDLIARGAPGVHLYTLNKAQACLDIVRDLDLEQ
>A0A1C0W2R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter pullorum|TrEMBL
MNKIENFIQILKSNEKCFTYEFSAPPSFSLDTFFDALQQENLVSKIHAFICTDSPLAKLK
HNSILASLKLQNTFNLPSIATISMRDRNTLAIQSELIGMNSLDLRLILALTGDPIRHGNQ
PQAKGVFEGNSLLLLKIIQQLNQAKDINNHPIQGDFKPFYAFSVLNSYSNKKENLYKKMQ
EKIQNGASAIITQPIYDLDIAQELLQWCDKINQESSTNCTLIFGFFPITSYKTALFLHNK
LPGVFIPQSWLETMEKASHNNTELEIGLEKSQRLFENLCKIQAKIHLMSSNKVDIIGKIL
NGR
>A0A4R0DNA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4635|TrEMBL
MSALSHYLQQQQFCLVLEQIVSKRTELPPISTLAGLPCVMAFADRVHADDDPSPITLAQS
VSTDQAKLLHFSGKARDVKDLQQFVEQAKQQNMHDLLLLTGDKLKQHNFGKQDPRQRTRY
LESVSALMWVKAHAPDMYCGVAFNPFKYTDSEEQAQYLKFEKKQRAGADFVITQLGYDLN
KILKFKQFVDTSTQSFPVLACVMPLTYRRAKFMVKQQVAGIEISPHLLQHLKAEQQQNAA
WAEQRVYARAALQIWIYRHWGLAGIHVSGCQNPEQHALLEQALAQYQKWTLEQCLMEWNH
LCKIVRGDEMQPDLSTAYPQQQPSVLKYQVLQVTHDWLFDSALAQKIGRFVFQLGFWQQG
LAAKSILAVEYVSKHAAVGCESCGQCRLAETLYICPETCPKGLANGPCGGTKLDRCEFAD
RECIHSQKYRLAKQVKQQDILRRELIPAVPVELRQTSSWVNWFNPKSH
>A0A8H7P890|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Postia placenta|TrEMBL
MKISQKIAQAEKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQKLIGIETCMHLTCTNMPKEKVDIALKEAKEHGCRNVLALRGDPPMGKDE
WEAVEGGFVHGIDLVQHIRTKYGDYFDIAVAGFPQHQLLPPDELALELKYLKEKIDGGAN
FIFTQMFYDVDIFIQWVHSVREAGITVPIVPGIAPIQTWNGFHKATSLAKTKIPQSFLDE
LEPHKNNDEKVREIGTRLVAEMCRRILNEPIGIKGLHFYTMNLEKATRMLLEELNLVPRI
QTVKPLPWRQSLTPNRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQTKEEALQLWDHPTSADEIGKLFAKFCQGQLPALPWSDSAPSSETTVIATQLF
KLNEIGFLTINSQPAVDGARSDDRIHGWGPSNGYVYQKAYLEFFVSPQLLDALLPHIERD
VNITYYVINKRGDLRTNTHSDGPNAVTWGVFPNKEIIQPTIVEAISFMAWKDEAYELGRQ
WAKYYEPESPSRKLIDNIMDTYYLVNVVHNDYKKPEAIFEPFFKAGAELAASQGSQPVLN
GH
>A0A0J1IFU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niallia circulans|TrEMBL
MNFLDRLKNEILIGDGAMGTLLYSYGKDTCFESLNLSHHEQIEQVHQAYIHAGADIIQTN
TYAANYLKLQRYGLEDNVKEINSAAVKIAKKAVENKNVNILGTIGGNRGVKPQAISLEEL
KRSFREQLYCLLLEDVDGILLETFYDLEELETVLQITKKETDIPVIAQLSIHEIGILQNQ
ISLASAFDRLENLGADVIGLNCRLGPHHMIASLEQIPLPKNAYLSAYPNASLPSYIDGKF
EYKDNAEYFQKSAEEFRKQGVRLLGGCCGTTPEHIRNFAKVLKEASPITEKTVATNKTAV
DAIFHHSSPPRDYTPLEEIVKTRASVIVELDPPRKLDTTRFFEGAKKLKEEGIDALTLAD
NSLASARISNTAIGTLVKQNIGLRPLVHIACRDRNIIGLQSHLMGLHTLGIHDVLAITGD
PARVGDFPGASSVYDMTSFDLISMIKQLNEGLSFSGKNLGQKTTFSVSAAFNPNVRQVEK
AVKRLEKKVACGADYIITQPIYSEQKIIELYEATKHIDIPIYIGLMPLTSSNNAEFLHNE
VPGIKIDDSIRRTMAQFKDNPEQAAQEGLKITKSLIDTAANYFNGIYLITPFLRYELSVE
LARYTKLRTAALRRTTDATNFIS
>A0A6L6XXN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. MAH-18|TrEMBL
MVDSQARRIGDLVRSGERSFSFEFFPPRDAAGEEQLWQAIRELEPYRPTFVSVTYGAGGS
TRDTTVRVTGRISRETSMTAMAHLTCVGHTQAELDGVLDAYAEAGIANVMVLRGDPKEGP
RAEWTPTEGGFTYAEELVTRARQRGGFSIGVAAFPEGHPSAESLDHDADVLVAKARAGAE
FAVTQMFFRAEDYFGLVERVRARGCDLPILPGIMPILNLANIRRQGELIGTDVPASVVDR
ILAHDGDAVAMRAAGIDLAAELCEELLEGGAPGLHFYTLNRSKATREIFARLNIAA
>A0A752IAK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella gallinarum|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2W5URU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cereibacter sphaeroides|TrEMBL
MSTTPRVSFEFFPPQTLDASFRLWETAQMLAPLNPSFVSVTYGAGGTTRRLTHEAVTAIG
HNYGLNVAAHLTCVDATKSETMAIAQSYADAGVTEIVALRGDAPKGAKRYVPHPLGFANS
VDLISSLAATGKFKLRVGAYPERHPDAADATADVRWLKRKIDAGASSAITQFFFEAETFL
RFRDACAKEGITAPIIPGILPIISWDGAKRFAARCGAKVPHRLDEAFETATRDGRADLLA
LTHCTTLCTRLIEEGVEDLHFYTLNRPHLTREVCHALGLTTPVALEMVA
>A0A081RSG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus temperata subsp. temperata Meg1|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSIGRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWNNGIRHIVALRGD
LPDNSEKPKMYGADLVELLKKEADFDISVAAYPEVHPEAKNSQADLICLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQLKRFATMTNVRIPSWMTRMFE
GLDDDPESSNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A374WRK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. OM05-10AA|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEIAKIIY
>A0A3Q9UJ25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidipropionibacterium jensenii|TrEMBL
MQPTRTSTATIADLLARPGRPLRSFEFMPPRSEEDVYRLWQATDSLVSLGPDFISVTYGA
NGSNRDRTLRCTRHMVASGLRTVGHLTCVSQSVAELEQAVCDYRDAGVDHILAIRGDMPG
GATEPWLARPDGLANATELVRLVKRVNPQACVGVGAFPDGHPASGDLDLDARILADKARA
GASFAITQLFFIPEHYTRLVARVRALGCDIPIIPGIMPITSYGQIRRFGDLSGTDVPADL
VARLTRVADDRAAVREIGLEAAAQLCCRLLDEGAPGLHYYTLNRSRATTELHSMVRDRRP
QLWDR
>A0A2N3D2T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HGW-Alphaproteobacteria-15|TrEMBL
AAELCRRLYAGGVRDFHFYTLNRPELAYAICHLLGKRRIGEAA
>A0A3R8P220|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora rhizosphaerae|TrEMBL
MASELRRSLDRMRYEVLPVGKARLDLLDPGSTVTVTASPVRGIEPTLAAAERLSANGLHA
VPHLAARSFRDHAHLATALDRLDAAGVSEVFVIAGDGAHPLGEFADSLALLRAMEQLGRL
PARIGIAGYPEGHAFLPDDCTVRAMEAKARYADYVVSQITFDARTITEWARDVRLRGVQA
PVYVGVPGVVDAHRLLRIALKIGLGESTRFLRKQYGAVSKMLARYTPEDLFDELSPQLAD
PESPIAGWHLFTFNEISGTVQWRDDLAVRLSGYADRPA
>A0A0Q8INE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp. Root685|TrEMBL
MIDDDLRASRLTADKRPELQISFEFFPPKTDAMEEKFWESIGKLAPLKPRFVSVTYGAGG
STRERTLRMVRHITSDTGVPAAAHLTCVGASKGEIDEVVRGFAEVGVKSIVALRGDPPEG
IGQPFSPHPQGYQNAADLVAGIRKLGDFDISVAAYPEKHPQSASWDEDIDNLKRKIDAGA
DRAITQMFFRNSDYLRFVERARKAGVSAPIVPGIQPIHSFKQISGFAARCGASIPDWLAE
RFSGLENDPDTHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRPD
>R5JM27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides eggerthii CAG:109|TrEMBL
MHKRIACPSGHFSFLFRIFVPNVQGFCQLDKDNEEEMRVIDLINSNEKTAFSFEILPPLK
GTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDLGNGLFQRNRLRRRPGTVSVAAAIQ
NKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDLLVLRGDKAKHESAFTPESNGYLHA
IELQDQINQFNKGIFVDGSEMTVTNTPFSYGVACYPEKHEEAPNIDTDIYWLKKKMENGA
EYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKPFKKLSQLSMIPKTFKVDLPEELTK
EVLKCKNDAEAQQVGIEWCVQQCKELMKHHIPSIHFYSIGAVNSIKEVARQIY
>A0A7H8GRU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 43A|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>R5TEW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:50|TrEMBL
MIREYLKEHILITDGAMGTYYDRKKSENGRIAEEANLLEPELITRIHEEYLEQGARLIRT
NTFAANHAMALGRGIRDRREQDAYVKHVIRAAWKLAQKAAENRPEEIFVAADIGPVAENL
FSEYETDPAAEYRFLADCFLECGAQIFNFETFSDIKYVAKTARYIKEKCPEAFVMVSFAA
NRNGYTTQGISISRLFAEAAQTPEIDSYGCNCLLGAAHMYKLIKAQNLAGDKFIQVLPNS
GYQQIVRGQAGHADGVHYFADKMEQMAELGVNIIGGCCGTTPKHIRMLCEKLAGKAPYEK
LPVVEKGGEDAVSQTRNNPFMAKLQRGEKVIAVELDPPFNQDAQKLMEGAFQLKQSGVDI
ITIADSPLARARADSVLLAAKVSAMVDIPVMPHIACRDRNRISMHSTLLGAHINGIRNLM
IVTGDPVPSGERDNTKSVFDFNSIRFMEYVKELNQEIFLQDAFSYGGALNQNQANEDQVM
KRMQKKIDAGLSWFMTQPIYSDEEVEKLGRMKQELNTKILCGIMPLVSYRNAMFIKNEMP
GIQVPDEIVAQYRPDMSRAEAEDVAARISLSIMEKLEEVADGFYFMTPFNRVSLITRIIH
ARKPQ
>A0A6S6MUU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium vitis|TrEMBL
MAHTSSNRDQARPFKLSFEFFPPKSEEMEAQLWATVDELTDWEPEFVSVTYGAGGTTKAP
TLAAVRRLLAETPLATASHLTCVGATREEIAQVVEDFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGFENAAALVKGLKELGDFEISVSAYPEKHPESADLAMDLDMLKRKVDNGATRALT
QFFFDNDIFERYLDKVRAAGINIPIVPGIMPILNLTQLKRFAGMCGTSVPAMLDQRFEGL
DDKPTERASVAAALAAEQIADLQGRGIDEFHIYTMNRAPLVNATLERLGLQRSDTVAASR
AGVVA
>A0A1U7W7S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nicotiana sylvestris|TrEMBL
MKVIEKIQEAAKDENRVVFSFEFFPPKTEDGVENLFERMERMVAHNPSFCDITWGAGGST
ADLTLEISKRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKINGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDVIPANGIATQEIYENDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPEEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKSALSILMN
LGLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTLGWDEYPHGRWGNAQN
PSYGALSDYQFMRARSRDKKLQEEWVVALNSVEDTYEKFKDYCLGKLRSCPWSELDGLQP
ETKIINEKLGHVNTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSGEKL
NTLVEKCKAFPYLTYMAVNKEGNWISNISQTDVNAVTWGVFPAKEIVQPTVVDPASFMVW
KDEAFEIWSRGWAQLYPETDPSRKLLEQVQNSYYLVSLVDNDYINGDLFSIFQDI
>A0A3B4XRB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Seriola lalandi dorsalis|TrEMBL
MVNQVQRGEGNWQSCKSDSSGASNSGGESSKESSRCSTPVLDADRSDRLRDKMRRRMESG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKDKITGYLAKAKHLGLKNIMALRGDPVGVDWEEEEGGFNYAI
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEQDLRHLKDKVDAGADFVITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIQQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWTEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLQMWGEELMNEESVFEVFTCYITAQPNRSGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPSINGKPSADPVVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRV
NYHIVNVHGRNLTNAPELQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPETLSDLTVS
E
>A0A1S7TK15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium deltaense NCPPB 1641|TrEMBL
MPDISAASIIPASIEASPAQVLGSTDLAGLFPQGVRVYLTDTGAASQERLVEAAGHLRDL
GYEPVPHLAARRIPSRAAFEEQVKRLAGEAGVTDVLVVGGGVDRPAGTFASSMDMLSTGI
FDRCGIRQIAIAGHPEGSPDFNDETAMAALRLKRDFAERSDAAMRIVTQFGFDPARFIAW
AEGLAASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTTLAKGHSPES
IVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGAVDRSASPDSMAG
>A0A640XJW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Brocadia sp. AMX2|TrEMBL
MDLKSGSNLEKVLQSGQFAVTAELGPPRGADRSVIEKKAGLLKGYGDAFNITDCQTAVVR
MSSIAAGRIVLDAGLEPIIQMTCRDRNRIAIQSDLLGAAALGAKNLLCLTGDHQKFGDHP
MAKGVFDMDSIQLIQMVKAIRDEKKFQGGQELKASEPRFFIGAAENPFADPFKFRAIRLA
KKIAAGADFIQTQIIYNINKFKDWMKMVTDMGLHEKAFILAGVAPLKSAGMARHMKHNVP
GMDVPDEVINRMTAVSAAKKGKEEGIKICLEVIEQIREIKGIAGIHIMAVEWEEAVPEIV
KETRLYPRPLL
>A0A1S2DUT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium vitis|TrEMBL
MAHTSSNRDQARPFKLSFEFFPPKSEEMEAQLWATVDELTDWEPEFVSVTYGAGGTTKAP
TLAAVRRLLAETPLATASHLTCVGATREEIAQVVEDFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGFENAAALVKGLKELGDFEISVSAYPEKHPESADLAMDLDMLKRKVDNGATRALT
QFFFDNDIFERYLDKVRAAGINIPIVPGIMPILNLTQLKRFAGMCGTSVPAMLDQRFEGL
DDKPTERASVAAALAAEQIADLQGRGIDEFHIYTMNRAPLVNATLERLGLQRSDTVAASR
AGVIA
>A0A150X7H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivirga ehrenbergii (strain DSM 102268 / JCM 13514 / KCTC 12282 / NCIMB 14502 / KMM 6017)|TrEMBL
MKVTQHIKRAKGKTLFSFEILPPRKGENVNGIFDAIDPLMEFNPPFIDVTYHREEYIYKQ
HDNGLLEKVTTRKRPGTVGICAAIMNKYGVDAVPHIICGGFNKEETENALIDLDFLGIDN
VLVLRGDAIKSEGRFVPDPEGHSYATELMQQVLDLNQGKYLHEEVEMAKTNFSIGVAGYP
EKHFEAPSLKSDMKYLKQKVDMGAEYIVTQMFFDNQKYFDFVEKCRKADINVPIIPGLKP
LTTLNHSTILPSIFHVDLPDDLVDELDKCKDNKAAREVGIEWCIQQSKELMEAKVPCLHY
YTMSKSSVIKQIAEKLF
>A0A0K3C8H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosporidium toruloides|TrEMBL
MVKISDKIKKAEREGRPWWSFEFFPPKTPEGWVNLYDRIERMQQLGPIFVDITWGAGGST
SEATTNFVKTAHSELGLETCMHLTCTNMPVEMVDKALKEAYDSGCRNILALRGDPPRGVE
EWKPTEGGFNHAIDLVKHIRKNYGDYFCIGVAGFPEGHPQSESPEAEIRHFKKKVDAGAD
IVFTQMFYDAEVFIDWGRRLRAAGITIPIVPGIMPIQTFAAFKRRTDFAGTIVPKELWDL
LEPIKDDDAKVREVGTKYVADMCRKILNADLGIHGIHCYTMNLSRGTEMLLEEMQFVPTA
DRVKPLPWRLSLTQKRRAETTRPIFWSNRQKSYITRTRDWDEFPNGRWGDASSPAFGDVD
ALLLALPHKPQDAIKLWGKPHSLGNITALFARFCRGDLKSLPWSDQPAAKETTRIAEQLA
RINELGFLTINSQPRVDGAPSEDPAVGWGPIRGYVYQKAYLEFFCPPELVEPLLELLGDT
PSVTYHAVNKQGDFRSNTAPGPNAVTWGVFPGAEVIQPTVVDSTAFQAWKDEAYELGWQW
AQLYKETAPETYEVISRIFSEFHLVNIVFNDYRNTDEDAIFKPFFELAHRKGLSVANGH
>A0A0K3C8H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodotorula gracilis|TrEMBL
MVKISDKIKKAEREGRPWWSFEFFPPKTPEGWVNLYDRIERMQQLGPIFVDITWGAGGST
SEATTNFVKTAHSELGLETCMHLTCTNMPVEMVDKALKEAYDSGCRNILALRGDPPRGVE
EWKPTEGGFNHAIDLVKHIRKNYGDYFCIGVAGFPEGHPQSESPEAEIRHFKKKVDAGAD
IVFTQMFYDAEVFIDWGRRLRAAGITIPIVPGIMPIQTFAAFKRRTDFAGTIVPKELWDL
LEPIKDDDAKVREVGTKYVADMCRKILNADLGIHGIHCYTMNLSRGTEMLLEEMQFVPTA
DRVKPLPWRLSLTQKRRAETTRPIFWSNRQKSYITRTRDWDEFPNGRWGDASSPAFGDVD
ALLLALPHKPQDAIKLWGKPHSLGNITALFARFCRGDLKSLPWSDQPAAKETTRIAEQLA
RINELGFLTINSQPRVDGAPSEDPAVGWGPIRGYVYQKAYLEFFCPPELVEPLLELLGDT
PSVTYHAVNKQGDFRSNTAPGPNAVTWGVFPGAEVIQPTVVDSTAFQAWKDEAYELGWQW
AQLYKETAPETYEVISRIFSEFHLVNIVFNDYRNTDEDAIFKPFFELAHRKGLSVANGH
>A0A1J5M013|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium MedPE-SWsnd-G1|TrEMBL
MKVTDHIKNANGKTLFSFEVVPPVKGQNIKDLYDNIEPLMEFQPPFIDVTTSREEYIYVK
RENGLLERKVTRMRPGTVGICASIKHKFDVDTVPHVLCGGFTKEETEYVLVDCQYLGIDN
IMALRGDAAKHEQYFKPTEGGNAFASDLVKQISELNKGNYLHDEIETKHTSSFCVGVAGY
PEKHMEAPSMQTDLMRLKEKVDAGADYVVTQMFFDNQKFFEFCDAAKAMGINVPILPGIK
PVAVKRHMQILPQVFSLDVPEALIKEVQKCSNNKEVRQVGIEWAIQQSKELIAAGVPGVH
YYSMGKSSNIQAIAKAIF
>A0A327SZB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DpondAA-E10|TrEMBL
MTGAADEGLRAALTRSTPTFSFEFFPPRTAAGSRALWNAIRRIEPLAPDFVSITYGAGGS
SRDRTVEVVRRVVTETTLRPVAHLTAVGHSAAELRRVVGRYADAGVRDVLAVRGDPPGDP
RGAWSAHPDGFTHAYELVELIRSLGDFTIGVAAFPERHPRSTDWESDIRHFVAKCRAGAD
YAITQMFFDVEDYLRLRDRVTAAGCDIPIIPEIMPATDVRRISRFVELSGCAFPEDLAHA
LEAARDDPAAGHRVGVEHATAMAERLLAEGAPGLHFITLNSSTAATDIHRTVAPARPVPP
AGTGAVRGALPAGGAPVGLPGQA
>A0A7C4AUN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MKITEIVSTARPTISLEVFPPKDVAGWESLKKNLKILSKFHPAFISVTYGAGGKNRRENL
TLLKMIKQEMGLEVLAHLTCVGQTREEISEIIQQLQENKIENVLALRGDLPSGQKNHGDF
QHATDLMEFIRQIDETFCVGVAVYPEKHPESLDWAAELKYLKRKVDLGASFGISQMFFDN
QIFQKFLRRLKDNHITLPVIAGIMPLMSEKQIKKITALCRATIPENLLDKIVNAPDEETA
REVGTRFAIQQCQELLAEGIKHLHFYTLNQSASVSRIIPHLDLL
>A0A847FGK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MSVLRKKIKAGEFVVTCELNPQKGGDFGELLEAASSMRGRVDAFNVTDSHAAVMRQSPLA
LCLRLKDAGLEPVYQLTCRDRNRIALQSDLLAAAALGIKNVLALTGDHPLLGDHREAKPV
FDLDSVQLLSVFSAMRGGKDMRGHSLSGASPDFFCGAVVNPGADPQELELMKMAKKAAAG
AEFFQTQAVFDAESFAAFMRRKPVSDSRVLAGILPLRSARTARYLNRRVPGVNVPERLIK
EIESSGDNENAAEKIFSRLIGEIKPMCAGIHLMPAGWFSIVPRLLEAAGR
>A0A6N7LZC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MLSEALKSGKFVVTSEIGPPKGVEMREILSEAEFFKGKVEAVNVTDLQSSVMKLGSLATC
RLLIESGVEPVFQITCRDRNRLALQSDILSAYVLGIRNLLILTGDHPKLGDDPAAKPVFD
LDSVQLLEAVKKLQEGEDMAGNKLEGEPPKFFMGAVVNPGADPIEPQIIKMEKKIKAGAQ
FFQSQAVYEPEKFAQFMKKVKGFGVPVLAGIVLLKSAGMARYMNKNVSGVYVPDPLIEEM
EKVEKEKRGEKSIEIAARLIRELKGLCQGVHIMPLGWGNKVPKVLEAAGL
>A0A7C2UMC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MESQKRYRRTFSFEFFPPNTPEGQQKLRETTRQLAQLNPEFFSVTFGAGGSTRERTLGTV
LDIRAQGYEAAPHISCIASTATSVREMLQRYKDSGIRHLVALRGDLPSGLAAPGEFRYAN
ELVAFIRREFGDAFVIEVAAYPEYHPQARSAQDDLLNFKRKVEAGANSAITQYFYNPAAY
YHFVDQCEAMGVTIPIVPGVMPIGRFSQLARFSDACGAEIPRWIRRKLEGYGDDTESIRA
FGLDVVTALCDELLRNGAPGLHFYTLNQASLTTTIWRRLGL
>A0A7X8A2Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MKISEIIKKKKTFSFEFFPPKEESQNESFAKNLKDLIPLKPDFVSVTDTGYSAAKYKHLA
LSMLLKEKAGFDVILHLTCLNSTKREIGTVLEKAKAAGIENILALRGDPDPNREILPGDF
SYASDLIKEINLSHFCAGAAAHPEKHPLSASLNEDMSILKMKADLGVSFFITQLFFDNSV
FFRLRDDLAKNNIFVPLIAGIMPLASPLSLLKIEEKTGKISKPKALIEIMEKYSQDKESF
FKASVEFSINQCEELLSKGTNALHFFTFNKAKAVKEILGAIK
>A0A7C6ZJL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MSEENGNRSGLKTDSRIEKLLSQGHFVVTAEIGPPKSASPKGIIKNATLLKDAVDGMNLT
DNQTAIVRLSSIAAAVHVMSAGGEPIIQMTCRDRNRIALQSDLLGAASLGIKNVLCLSGD
HQSFGNHVTAKNVYDIDSIQLVSMVKTMRDEKKFLCGEEMKVEPRMFIGAAANPFADPFE
FRVVRLAKKVAAGADFIQTQAIFDIERFKRWMAMVRDQGLHEKVAILGGVLPAKSFGAMK
YMKDVPGMSIPEDLLKRMKGTPKEKQPEEGIKICAELIQMIREVPGVRGVHIMAVMWEET
VPEIVKMAGLLPRPSVA
>A0A661WYI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlamydiae bacterium|TrEMBL
MIMNFIDKLKNDIILGDGAMGTVLYSRGIFINRCYEELNLLQPEVIEEIHSEYINAGSDL
IETNTFRANSISLLKYGLADKTEEINVKGAEIAAKAAEKCNRKIYVAGSIGPTGLILENE
IQNSRDEAATAFTFQAQSLVKGGVDVIILETFYSIDELSLAVESVKKAVKLPVIAQFAFD
SNKTTNYKSKGITPEKVALKLVGCGADVVGTNCGAGPAALLSIVERMSSSTDLPVSVFAN
ANVSEMHEGRMITLGTSSEYVAEYARRYAQAGAKIIGGCCGTTPETISEISRFLKGVVAE
QRSQIFVKEKIDFLKPIPLKKRSKLGKLIADKNLNRKLVSVELSPPTGIDPSRVIEGAKL
LKAGGVDFVNIPDGPRAVPKMSPIATAKLVKDSTGMETIVHYCCRDRNLLGMQMDLLGSS
AMGLNNLMLITGDPPKVGNVQSASPVFDIDSIGLINLVAGLNGGRGLAGVDLKCRTNFVI
GAGCNPGSVDIEEEVRRFEAKIAAGANFFFSQPVYLPELLDKFLEMTKHHSDIPLFVGVL
PLASLRNAEFLHNEVPGMQIPNEIMKQMRSAETKAQQQKQGIIIAQNMLKQIIMFPRVRG
IYLFPPFGRYESVLDVLEAME
>A0A8B5TZJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-3-15|TrEMBL
MTGRQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHDDITETQVDMVK
TAH
>A0A2N2W5L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-8|TrEMBL
MTVIEKIKNAKSPLFTFELLPPLKGHSIDKIYSSIEGLLEFEPAYINFTSHRNETLYRER
SDGTLERRVARIRPGTIALAAAVKYKYNITVVPHLLCGGFTKEETENALIEMNFLGIHDV
LALRGDPVKGTRMFIPERDGHRNTNELIEQVVNLNKGRYLDSSMESASPTSFCIGVAGYP
EKHFEAPNPEIDMEYLKKKIDAGADYIVTQMFFDNEKFYRFRDLCQKIGITVPIIPGIKP
ISALNDIKLLPQTFHIDVPQDLFKAVVKCKDDKEAREAGVEWATMQSKDLIKNGVPGIHF
YTLGRSDNVAKIVKSSY
>A0A521V2J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MLTSLEGGTRTAALEIAAYAAELLACGSIEMGAHQPQMARRIAALLPSGTPVFVNHLPRH
SLADALDSLFAVREAGLEPVPHLAARRIASRGELEAFLQRAVGAAGVRKVLLIGGDEIAP
LGPYADGAAALRSGILSACGIREIGIAGYPEGHPRIPAAALESSFTEKLALAASEGLGAF
VVTQFSFAPARVIEYCAGLARRAPGVPVYVGLAGPSSTAALLRFAQRCGVSASLRALRAQ
GFGAVQLVTHTDPGDQLTTIARYCMAHADCNVVGAHVFSFGAAVAGAEWMNRFIARST
>C4FMM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella dispar ATCC 17748|TrEMBL
MMTLREKHQQGKFTITVELDPPKSSSAQKVFDQAARLKGKVDAINIADSPMSKMRMSPIS
LSYLLQHNKDIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDNGDHPFAQS
VFEVDCMGLLNIAKTLNSGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNG
AHFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILD
RVEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A2T6F579|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciimonas sp. PCH181|TrEMBL
MSPQNFSIEFFPPKTPEGAEKLRVTRAKLAELHPKYFSVTFGAGGSTQKGTLDTVLEIRR
EGHDAAPHLSCLGSSRESLREILTQYKENGIKRLVALRGDAPSGYGAMDFSSSEFRYANE
LVEFIRTETGDWFHIEVGAYPEMHPQAKSPQDDVQRFAAKIKAGANGAITQYFYNTDAYF
RFVEEAQKLGVAVPIIAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLAAFGDDTESIRAF
GLDVVTQLCERLLAGGAPGLHFYTLNNAAATTAIWQRLK
>A0A536TZV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTGSANRIFSFEFFPPATPEGVTKLRATREQLERLGPKFFSVTFGAGGSTRDRTLAAVLE
IQGAGQRAAPHISCIGSTRESIRATLAAYREHGIGHLVALRGDLPSGTADVGEFRYANEL
VEFIRVATGDWFHVEVAAYPEYHPQSGSPREDLANFKRKFDAGADSAITQYFFNADSYYH
FVDEAVAAGIEAPIVPGIMPILSFSKLARFSDACGAEIPRWIRRKLESFGDDTASIRAFG
LDVVTDLCDDLLAHGAPGLHFYTLNQASLTTIIWQRLGLS
>A0A1N7H713|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia sterculiae|TrEMBL
MSVSPRCPKVYPLCPYAGPVSNASPQSSIVERLKHPGAVIHRPNSDPVPFSVEFMPPRDA
AAEARLWRAVRIFERMRPAFVSMTYGAGGSTRERTARITGQLARETTLLPVAHLTAVSHS
VSELRAMVGAYADEGITNILALRGDPPGDPLGEWIKHPDGVEYAEELVRMVRDLGDFHVG
VASFPEGHHRAPDLDHDTRHLVGKLRAGAEYSITQMFLDVDDYLRLRDRVSAMDPEQGRK
PLIPGIMPITSLKSLRRMVELSGASIPPAVEARLTAAAGDGPEEDREAVRAVGIDLATEL
SERLIAEGAPSLHFCCLNFARATSEVLTRLGLDVLTPVGG
>A0A3D2PAT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
VYEVDKFVKFMEKVKNFGIPIMAGIVILKSVGMAKYMNENVAGVFVPDNLIEELKKDKEK
TKSGQTGIEIAARLIKELKPYCQGIHLMPLGWNDKVPAILSQAGLI
>A0A432J7D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
DMLSGVACSTKTRRTTHPAQMHCSAGWMTNPPEFTFYTDFYMRFSSLYRAARHPVLSVEL
FPPKTEKRLSHLNKELSQLMRYPVGFVSVTYGAGGSTQTNTLQLVKNVRERYPVTTVPHF
TCVGASHENIRTFVEQAIAEGAENMVALRGDPPKGATNFQASPGGFQFAHQLVTFLKKNY
GDHLSLAVAGYPEGHVETRDLKRSVEHLKQKVDAGADLVITQLFYDNADFFRFREMAVRA
GVQVPIVPGILPITKYSQINHITKLCGAKIPKDLTQLLLAYDDGSVDQQMTGIAAAIDQA
GELLENDVPGLHIFTLNNSFATAHMVAALGHYFEQK
>A0A435KUZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.05.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>T5L4S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia MF89|TrEMBL
MPAGTSAHAEAFINAFSLEVSAKAMPALRAEADRIPRGTVISIPWLASEDDDARLAAVRT
VRALGFEPMPHLSARRIGSRTALERFLERATSEAGVERCLLIAGDLATPAGPFADSASII
ETGRLERFGIKVVGIGGHPEGHPAMSGDARWQVLERKCQAIEARRMAPVIVTQFAFDADA
VLAWLDALRARGISVPVLVGVPGPASVSRLLRYAAMCGVGASASMLAKYGISIGRLLGTA
GPEVFVDRLVKGLTRAHGQVSPHFFPFGGVAPSLEWVAQYRRRISISQRR
>A0A4R6Z4N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tahibacter aquaticus|TrEMBL
MSPSSPLSIPVSLEFFPPKTDEQRDSLEKALPALKALQPEYVSVTFGAGGSTLSYTPDTV
CQLRDDHGLDAAPHLSCMGGTRKEIRSLLELYRTKGCKRIVALRGDLPSGMAGYGEFRYA
SDLVAFIREETGDYFHIEVAGYPETHPQADDAQADLAHFKRKVDAGANGVITQYFYNADA
FFRFVADARRLGVQVPIVPGIMPITNYSQLRRFSEMCGAEIPRWVARRLQSFGDDAEAIR
EFGTDVVAELCRRLIDGGAPSLHFYTLNRAKATTAIIERLK
>A0A369GRR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps camponoti-leonardi|TrEMBL
MPLPATDEIMSLRQMTLQPTVAMDKITNKIAALPDGAEYISLEFFPPKTAMGFANLRHRM
QRMEQALRPLFVNVTWGAGGATAIKSLELAELCQRELGLTTCLHLTCTNMSRRLVDRTLE
DAKVLGIRNILALRGDPPRKEEYREAIGDDDDDNPVEFTWAIDLVRYIRSKHGDYFCIGV
AAYPEGHADGSHPLEQSLENDLPYLVDKVRAGADFIMTQLFFDMEAYEKFERTLRDHPSG
VFSTMPIIPGLMPIQSYQMIKRTTKLSHAKLPDAILARLDAVKGDDERVKKIGVDIVSEL
IEHIRAIRPPGSSSRRGFHFYTLNLEKSVSLIVEQTGLIQEDLSDEAVLDGLLSPPPTMH
SNGNRQTSHSRSSRRQSSVGSDPHNRVIVGDRPLTNPEWEATGQEAGVPASSVNSRANTL
AICEGEGVLGREATWDDFPNGRFGDARSPAYGEIDGYGVSLHMSVTQAERLWGHPTTAED
INRIFVRHVRGELAAIPWSEEGLMEESSTIRDRLVELNNKGWWTVASQPAANGAPSNDAT
LGWGPPNGFVFQKAFVEMFLPAEDWRRLLERLRSDSICFYAANAAGDFVSSDESGGVNDA
RVAPSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWGEWARVYGRGTASEKLLSG
IREDYWLVNIIHHEFLEPDALWDLLR
>A0A833G199|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bauldia sp|TrEMBL
VLALRGDPPRGEPDFTPPPGGLRSSAELASFIRGREASADIGIGASCFPEIHPEAASAEA
DIAFLGEKVDAGAEFLISQLFFDNAVYFDWVEQVRRAGIGVPIIPGVLPIISRAGLHRFC
DVCKARIPDRLDAQLAALDGDPDAERAFGIAYASRQCEQLLAAGAPGIHFFVLNRAASVK
AILGAIKAGRPWERTGGEIVAAARGTS
>A0A1F5AMK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium RBG_13_59_9|TrEMBL
MIENGTKRLRRLLSLPGRERPFIVLVELLPLAGHNLDNIEKFLTAYRAGKDALPDDVVLA
GITIPQNPSGTATMSPADVYSLLRMKDLWSDLDVMPHVTAKDHNTESLKTYLIGLQKLGL
ESVLALTGDKPSSGKRVFEVDSLGLIELIKEMNYESFSRTAPGRFDRVHQFYILAAVSPF
KYTEASLMQQYSKMEKKIRAGADGLITQMGWDSRKSEELFRYLETKGLRVPVLGNVFLLS
TATPAPRLMFEGKLPGCLVTKELFEKVSKETPADHLERAAQQVAMYRDLGAAGVDIGGLQ
DFSSLAAMLRRAREIGRDWRRFRPNLDFGVRGQADGRPGFYLFDETGRPQTTSRTRASLN
KKFFDFLHRNLMTPGRRLHPAIRKILGSSRSLRRGRGLLYRTAFAWEKATKSLLFDCEEC
GDCFLVENFGLCTLGKCEKGLPNPPCGDANPDGTCAHDPDNRCVGELIYEAAASEGAQGI
GTLSERINPKRDPALEGTASLLNYFFQKDHARKKSLI
>A0A1V5PTH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin354|TrEMBL
MKVSEIYKSGKRSLSFEIFPPKKEEELRDIDDTLDVLCELKPDFISVTFGAGGSSNCNRT
IELARKIKDKYKVEPVVHLTCLCYDKKEIDEFARVLNDSGIENILALRGDDREDIPRKTD
FMHASDMAAYLKEKNDFCILGACYPEKHPESEDLISEIHNLKKKTSAGTEVLLSQLFFDN
KIFYDFKEKCRIADINTPIIPGIMPVVKATQIKRMVALCNASFPERFQKIVDLYADRKEA
LFDAGMSYALSQIIDLIASGTDGIHLYTMNNPCIARRICEGIKNII
>A0A4U6HJR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. wls714|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A5ZMW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia obeum ATCC 29174|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSVGMVRFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>R7IFD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. CAG:74|TrEMBL
MRIASILNEKEITLSCEVFPPKHFDGIAQASAVAQEIAGLHPSFMSVTYGAAGSTPGHTI
AVAKAVAETGVTPLCHLTCVQSTREHVQHVLADMKTAGMENVLALRGDLPKEGEPCHDFA
YAAELIDFIHQQGDFCVGAACYPEGHPESGSRAKDMDYLRRKVDAGVDFLTTQMFFDNGL
LYNFLYRMQRAGMDIPVCAGIMPICDARQVARVVKLSGSIMPPRFAAIADRFAGDPQAMT
QAGIAFATEQIVDLVANGVGHIHLYTMNKPWIARAIVENLSSIIKLGE
>A0A137S526|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moritella sp. JT01|TrEMBL
MKYSIELVPRTWEILNTEVEEVSQFSQINTLNIPDLLRFDIRSWDACDRLQDKFDEVIPH
LRAIDFDLRSGFPLTDFFRHSKINSVLVVEGDPPQDISHRTYRNTSCELIRIIKKELPYM
KVYAAIDQYRTSMRKELDYIHDKIDAGVDGFFTQPFFDLKFLDVYMDMLQGTEVFWGMSP
IHSETSKSYWENKNDVVFPSDFEATKEWNINFGRAMIKKVQAKNDNVYFMPIRANASEYL
GNLLAED
>A0A1G5PZ40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epibacterium ulvae|TrEMBL
MSTPQISFEFFPPKNLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRELTRESVATLHK
TSGLNVAAHLTCVNASRAETLEIADQFAAAGVNEIVALRGDPPKGEGSFTPHPEGFANSV
ELIEALAETGKFKLRVGAYPDPHPEAPNAQADVDWLKRKIDAGADEALTQFFFEAETFFR
FRDACEKAGIDGDKITPGILPIENWKGARNFAKRCGTYIPAWVDEAFEKATRDDREDLLA
TAICTELCSELVDGGVERLHFYTLNRPELTRDVCFALGISPKVALEHVA
>A0A149QE62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter cerevisiae|TrEMBL
MSLSRLSVELIPRSEDALAQDVTSVKTLFPAADTLNIPDLMRFPLRSWDAAALTMPQFGT
VVPHVRAIDIAPGAPLPGSTLPGLKEVLVVHGDPPADLAHRTYPNSTESIIRRYRKEAPH
LRIYAAFDPYRRAPWRELEDIARKKDAGAEGFFTQPVFDLKLFDLCREWLQDEQVFWGLS
PVIGPRSRSYWETTNHVVFPRDFEPTLDANIQFAQSVLRQLSQDLGCAYLMPLRVKLDQY
LPPLMEALTA
>A0A0T6VHA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. TTU2014-105ASC|TrEMBL
MTTSRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDTKADLRELLNLYKEAGIQRIVALRGDLPSGMGMASGELRYANE
LVDFIRAETGDHFHIEIAAYPEMHPQARNFEDDLTNFVRKAKAGADSAITQYFFNADCYF
YFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIQSIQAF
GEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A3A5J8C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinisphaera sp. Q1T1-3|TrEMBL
MSEDVSHNDFSIELFPPKGPKGRARLESALAELGGLNPAFFSVTFGAGGTTRSGTLDTVE
LAMDITGRPAAPHLSCIEGTRESIEELLDNYKAAGVSRIVALRGDLPEGMEKPGVFNHAN
ELVSFIKERHGDDFHLEVGAYPEFHPAAASPETDIDNFVRKVRAGADSAITQYFYNADAY
FNFVDEVAARGIDVPIVPGIMPINDFGQISRFSAMCGADIPRWVRQKMEGYGDDTASVRA
FGRELVYNLCEQLLAGGAPGLHFYALNKAEPTATLWHDLKLPGTDNKAA
>A0A0F7VVE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces leeuwenhoekii|TrEMBL
MRDILAAGKTTYSFEFSAPKTPKGQKNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVKE
TQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVPHP
RGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVARFVDKCRAGADYAITQMFF
QPESYLRLRDKVAAAGCETPIIPEVMPVTSVKMLERLPRLSNASFPEELKERILAVRDDP
AAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHRPQD
>A0A380DJI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MQESFTHIELPEHAYLSCYPNASLLDIENSEFKYSDNAQYFGQVAQNLIREGVRLIGGCC
GTTPEHIKFIKESIQTLKPVNDKKVIPIPTKALFNPSQNKVRQSLTSKVQERPTVIIELD
TPKHLDTDRFFENIAKLDKANVDAVTLADNSLATVRISNIAAASLIKQYYNIEPLVHITC
RDRNLIGLQSHLLGLSLIGVNEILAITGDPSKVGHLPGATNVYDVNSKGLTELALRFNQG
INTDGDALKKRTHFNIAGAFNPNVRKLDGAVKRLEKKIESGMSYFITQPVYSKEKIIEIY
HATKHLNKPFFIGIMPIASYKNALFLHNEVPGIKMSDEILQQFEAVKDDKAKTRELSLKL
SKDLIDTVHEYFNGLYIITPFQNVEDSLELAAYSKSITAHKEAIL
>A0A371WRY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylovirgula sp. 4M-Z18|TrEMBL
MIAKPDRISRSALSSVNVSFEFFPPKTQEMEESLWDSISRLAPLSPNFVSVTYGAGGSTR
ERTHATVSRIVRETRMKPAAHLTCVGAARGEVNEVIRDYHGAGVRHIVALRGDPPTGIDQ
PYAPHPQGYQTTADLITGIKAIGDFEVSVSAYPEKHPQSPNLLHDIEILKRKVDAGADRA
ITQFFFDNSVYFRFLDVAAAAGINIPILPGIVPVQNFKQTANFARRAGSSVPAWLADRFD
GLDDDPVTRRLVAAAVCAEQVIDLIDRGVTDLHFYTMNKADLVFAICHLIGLRPQMAEAA
EAAA
>A0A258I1T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. 32-60-15|TrEMBL
MATPVIHPNWDKEPAGITDGFSLEMTAKDEASLRDAAPLIPAETPVAVTFLPGEDVAARV
AATVAVRELGFEPMPHFSARRITSEDDFEGYLRAVVEKAGVERCFIVAGDPPEPVGPYFD
TSALIATGAFERAGIKAIGIGGHPEGHPNMTTAECWAVLEKKVADITARGMAPLIVTQFG
FDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLSFAARCGVGASTSVLKKYGISVTN
LLGSAGPDKLVDAFAKGLGPEHGRVRLHFYPFGGLTKTLEWLHAYNKKHGIGA
>A0A139NE79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. DD10|TrEMBL
MSQHTPSLSFEVFPPNPAVGNEKILRALDDMQGLAPHFISVTASNNKYNIKETTVALANH
IQNELEVPTIAHLPAIYLTKESVAETLQELDEVGVHRILALRGDIIPEVAPQKDFRYATD
LISFIKEEQPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FRDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLKAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAQYIHEATRAFFHTGSGSKQLA
>A0A6H9YCJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium SCN1|TrEMBL
MSGRTFSFEFFPPKTAEGAEKLRATRAQLAQLKPKFFSVTFGAGGSTRDRTLEAVRDIQA
SGSEAAPHLSCIGSTRESIREILGEYKSQGIRHLVALRGDLPSGTMDAGEFNYANELVSF
IRAETGDWFEIEVAAYPEIHPQARAWKDDLANFKRKVDAGADSAITQYFFNADAYFRFVE
EVRALGVAIPVVPGIMPINNYLQLARFSDACGAEIPRWLRKKLESYGDDLVSIRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPSTTIWQRLGLS
>A0A151X708|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trachymyrmex zeteki|TrEMBL
MRNLILENDMCERNDADGNDNPSTPDFHTEDPRKTVVDLRRLLKDKISKNEIFCSFEIVS
TRKSGAFYRRLLIDMEEYSPLFYALTWHNEAASDNDGYLPLDLAENFPPNTLLHLAAKDL
KRDEVVYILKKALAFGIINIFALRGDSLSENGDFEHAVDLVAFIRQRFGDTFCVCVAGYP
QMHPESSSKELDLHYLKAKVEAGADFIITQICFDSRVLINFVRDCREIGIQIPILPGILA
PTNHACLEKMIDICRLDVPIKIKEDLARMKDDDQAARKYSVVLIAQIITDVIRNGATCGF
HLFTLNRLSLVAEICKRIESFKAKNL
>W2C792|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella sp. oral taxon BU063 isolate Cell 2|TrEMBL
MERVIDLINKSRGTAFSFEILPPLKGNSIQSVYRVIDKLRDFDPKYINITSHHSEAIEVR
GTDGMVRTVNLRKRPGSVAIASAIQNRYGIAAVPHLVCKGFTKDETEYGLIDLNFLGVNN
LLLLRGDVKRLHEPDNAELYHDHATDLQVQVNNFNRGIALDGSPITDIETPFSYGMACYP
EMHEDALSMDDDVRYAKLKVEQGAEYLVTQMFFDNAKYYAFVDRMRAEGVTVPIIPGIKP
IVLRDQLEVIPRIFHCTFPPEFAAALGRCRTDEEAKEVGVEWCTAQCRDLVAHGVPSIHF
YTLMASDSICRVAKEIY
>A0A177FED3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fonsecaea monophora|TrEMBL
MASEHDDRLPTLLSSLQPSSYYFSLEFFPPKTSSGFSNLQARLARMATALRPLFVTVTWG
AGGSTATKSLELAEVCQRQIGLTTVLHLTCTNMKRHMIDEALEGAKEIGIRNILALRGDP
PREEYKDATSTDDSESGSGGSGTESNQEFTWAVDLVRYIRRKHGDYFAVGVAGYPEGHAD
ESHPEQGKQSVEHDLPYLAEKVAAGADFIMTQLTYDIAAYAAYEERLRGYTDQDGKRLFE
KIPIIPGLMPIQSYQIIKRITKLSHARLPEDISERIERVKSDDEAVKKVGVDILSELVEE
MKTLTQPEGLPRGFHFYTLNLEKSVSFILERTGLIPTISSEGSVEDKDGDSASDSDVVVD
DSKQSTPAIVTTGLGEDRHEEQPSGFVRRRRSSVNAQPHNRVITDRRSEPRTESRRPDPD
SDPPGLGPNPNLKLTSQHLATDRGTGIPAASPTRQHSLLISEGQGSLGREATWDDFPNGR
WGPSHSPAFGEIDGYGPSLKVSPLMARKLWGYPRSRQDVTELFRRHVLGELAAVPWSDDI
DPDLVSPGGGSADGSTISSALRAETDVIRAELISLISRQNYWTLASQPAVDGAPSSDPVF
GWGPPGEGFVFQKAFVEFFCGRDEWEDKLRPRLMKHGSDVLGWMKTDAEGLFESSELVAR
DQARNQKTRAAADTEKENSKPASVSPGADQKVATSTSTSSPTNTVNAVTWGVFPSREILT
PTIIEAESFRAWAQEAYAIWNEWKRCFPRGSPESVFLEKMGKDNVLVNVVGQGFRGGHNG
GKGEGGRLWRILLGEDGDDKT
>A0A7W1VRN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MQFIRDIYSAKKATGQPVISFEFFPPKTEEGERTFFEKNVPALAALNPDYCSVTYGAGGS
TRDKTISIVDRIQREHNLPAMMHLTCVGSTAEQIGEVLDQAKARGIKNILALRGDPPNGT
AEFEKVEGGFEFSHQLVQFIKCRGDFSVASAGFPEGHIACKEGKYVDWQHLKTKADAGAD
FILTQLFFDNADFFEFRDYVTKLGVNIPIVPGIIPIQSANQIKKFTSLCGSKIPAALQTE
LDKYCDNDEACAEFGIEYAAKQCEELLRNDAPGLHFYTLNKARSTTQILKKLKLA
>A0A7V6YZX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MQLVRDIYASKRAAGKPVISFEFFPPKTPEGDRSLLEKTIPALKQTHPDFCSVTYGAGGS
TRDKTLMIVDRIQREHGLTAVAHLTCVCATRDDIRSLLEQIRSLGVKNVLALRGDPPGGG
EFKATPGGFEFASQLVAFIRQHDDFSIGVAGFPEGHIACKEGKHADWRHLKNKIDAGADY
VLTQLFFDNADFYEFRDYLQGRLGVTVPIVPGIVPILSGSQIRRFTALCGARMPAALLAR
LDELGDDDAAVTEFGIEYATKQCAELLRNGAPGIHFYTLNKSYSTVRVLQNLGLAPSARA
ATPASSGGVPPPV
>A0A014CNN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_7|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A4V0WML7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataeibacter diospyri|TrEMBL
MTLTSVELIPRDQETLLRDAGDVSRLFPDAQMINIPDLLRFPIRSWEAAALIRPIFPRVI
PHIRAIDIAPDAPLPGADDPGLHEVLVVKGDPPTDLKHRTYPNTSESVIARYRREAPHLT
VYAAFDPYRRAPYKEMESIVRKKEAGAAGFFTQPIFDMRMLDLCMNWLHGENVFWGISPV
VGPRSRSYWETTNHVIFPHDFEPTLDANIAFARQMMDAVAQEGGNTYLMPLRVNLERYLT
PLRR
>A0A1J1DWS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ichthyobacterium seriolicida|TrEMBL
MKVSQHIEESEKTLFSIEILPPLRGENINYIYENIDPLIKFDPSFIDVTFHKEEYLYEKK
DDGSTRKKIIRKRPGTVGIAAAIMNKYQIDTVPHILCNGSTKEEVENMLIDLNFLGIENV
LALRGDFSQGESSLVHENGDNKYASDLVKQINEMNNGRYLNDLKQDDTNFCVGVAGYPEK
HSEATDLNTDIKHLKNKVDQGADYIVTQMFFDNSKYMDFVDKCEENDISVPIIPGLKPIS
TKKQLKVLPEVFDIEIPEDLQKEVIKCKDNKQVRQVGIEWAVYQSKELVANNAPVLHYYT
MGRSSNIEEIASKVF
>A0A2V2BWH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MQNIGNTIAEKFGKGRTVFSVEFFPPKTEEGARQILRTANRLKKVRPDFVSITYGAGGSS
RERTLEYGELLGEIFGFEVMPHLACYGHSKSEIASILERFDSAGFRNVMALRGDKPKDGS
VSAHPDGFAHADELVGFVREKFPHFGIGCAGYPEKHPEAPDMRADIANLKRKVDAGADFV
TTQLFFDNSHYFRFVEMCRGAGIDKPIVAGLLPALSLKQLVNFKAMCSTDVPRALSERLE
AAGENPDAQAAAGLEWAREQIDELLEAKVPGIHLYILNRAESALKLSEKFGGRGER
>R6VYP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. CAG:268|TrEMBL
MNVVDIINEAIASKRTRFAFELLPPLKGDGMQKIFAAIDPLMPFDPAYINITFHREGIKE
TERPDGGIEWHVVRRRPGTVGISAAIQHRYGVEVVPHLICGGLSKYDIEDTLIDMDFLGL
HNVLALRGDKSQNERRFMPHPQGHAHAVDLVRQIAAMNRGEFVDGEVEECHHSKFSIGVA
GYPEVHFEARDITTDILHLKEKIDAGAEYVVTQMFFDNRKYFDFVRRCREAGIRVPIIPG
IKPISTLRHLEVLPETFGVELPGELVREARAHPDNVREVGIEWTVAQSRELMAAGVPVLH
YYTMSRTNNIQQIVRTLF
>A0A3E1EMQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MPIDHPISELFAQQRPLRSLEFFPPRDEAGLTALRATAVALAKIKPDFVSVTYGAGGSTQ
ERSAQVSEFLRGECGFTVMPHLTCVGHSRAELADIADRIHAGGFRNIMTLRGDPPSGTTT
FVPYQDGLRYASDLVALLKSRHPDFCLGVGGYPEKHPEATSAEADLANLKRKVDAGASFV
TTQLFFDNDLYYRFVDQCRAAGITVPIVPGLMPVLSLKQIQRFTTMCGASLPQKLVTRLE
HAAEHHEVVESVGIDWALTQIRDLLAQGAPGYHLYIMNRAKSALALAAGLAA
>A0A0X3TWQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria profundi|TrEMBL
MTKPEISFEFFPPQTLEASFRLWDTVQTLAPLEPRFVSVTYGAGGTTRELTRDAVSTLHK
SSGLPVAAHLTCVDASRQETLEIADTFAAAGVQDIVALRGDPPKGQDQFVPHPDGFAHSV
ELIEALADTGKFNIRVGAYPDRHPEAQDFAADIDWLKAKFDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGILPIENWKGARNFARRCGAHIPAWIENAFDKALRDDREDLLAT
ALCTELCSDLIEGGVDKLHFYTLNRPELTRDVCFALGITPRAALQNVA
>F2JZV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1)|TrEMBL
MTTELASKFQDPTRGVYFIGTTPPKLSTEEDKLQEISAKLLGRLSELEYDGMIVYDIQDE
SSRIAKPRPFPFMETHDPRAWSKRLSKLSERPVITYKSVAARSKAEFSNWLDEAWNVYGI
RDLVLVGAPSSDGQISLPLPQAYEALENAPQPFNLGGVTIAERHAKKGDEHKRLLKKSES
GCDFFVSQAVYNPQATIDLISQYARSCKEQDITPKRIILTFTPCGSTKTLEFMEWLGISV
PDATKHRILDAKKPLEESIRICRAALEQIIETALPLGVPLGLNIESLTNRKEEIDASIRL
YKLLKATLDLKLAEQQIK
>A0A449I117|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides heparinolyticus|TrEMBL
MRVIDLINSHEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLYQRNRLRRRPGTVAVAAAIQNRYNITMVPHILCSGFTREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFTPEGNGYHHAIELQEQINNFNKGIFVDGSEMKITKTPFSYGVACYP
EKHEEAPNIHTDIYWLKKKMETGAEYAVTQLFYDNCKFFDFVERARLEGITIPIIPGIKP
LKKLSQINMIPKTFKVDLPEELTKEVLKCKSDKEVQQVGIEWCVQQCKELIAKGVPSLHF
YSVGATDSIKEVARQIY
>A0A454JJU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquitalea sp. MWU14-2217|TrEMBL
MNEPKKTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGHAAAPHLSCIGSTRENISAILNEYRNHGIRHIVALRGDMPSGMVAAGEFRYANELV
EFIRSEHGEHFHIEVAAYPEFHPQSKSAEDDLNNFVRKVKAGANSAMTQYFFNADAYFRF
VDEAQARGVDIPIVPGIMPIANFGQLCRFSDMCGAEVPRWLRQRMQSYYDDTASIRALGL
DVVTELCDRLLANGAPGLHFYTLNQAGLVSTVWQRLGL
>A0A1Q5LPV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02400|TrEMBL
MTFRGWCGQAGRHASTDGSPTFSFEFFPPRTAQGEQTLWWAIRRIEALAPDFVSVTYGAG
GSSRERTIEVTRRVRAETTLRPVAHLTAVGHSVLELRHIIGEYADAGIHDVLVLRGDPPG
DPNGPWIPHPDGFTHAYELVELVRSLGDFTIGVAAFPERHPRSPDWESDIRHFVAKCRAG
ADYAITQMFFDAEDYLRLRDRVAAAGCDIPIVPEIMPAIDVRQIRRFAKLSHAAFPEDLA
HRLEAVRDDPVAGHRIGVEHATAMAGRLLAEGAPGLHYITLNKSTAALDIHRNVLSARSL
RVS
>A0A1E1F266|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium cloacae|TrEMBL
MTLHFPSVEEARRALDAPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLGPKFV
SVTYGAGGSTRERTHNTVARIARETPLAAAAHLTCVAASKDEIAEVADAYWDAGVRHIVA
LRGDPPEAGKRFEPHADGYQGAAELVEGLVKRHPFEISVAAYPETHPEAVSAKSDIDNLK
RKLDAGATRAITQFFFEPDSFFRFRDTVAAAGIGADIIPGIMPVSNFAAVQRMSAMCNTN
VPTWMGRLFEGLDTHPGARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPEKRA
>A0A2V6HF84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRGDSPTFSFEFFPPKTPAAAEVLYQTIRDLESYTPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEDEIEAILLRYARSAIGNILALGGDRPRDIPYDKSR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHFKAKVDAGA
DYIVTQLFFDNRDFLDFRERCAVADIHVPIIAGIMPVTSMSGFKRIAELAGGARFPAKLL
RALQRCQNDPEMVRRVGVHFALEQCHDLLDDNVAGIHFYTLNRSDATRVIFDSLGIPRRQ
SAQAPTVQSSDEVRKRLAT
>A0A0M3BRB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. LC145|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLSTVRTMRDEAKFLSGRKLTTPPHVFLGAA
INPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGFHEKCFILVGVG
PLASAKTARWIRSNVPGIHIPDSVIARLEGAQDQKREGKQLCIDIINEVKEIEGVSGIHV
MAYRQEEYVAEIVHESGVLKGRRPWKREANPTDALVAERLEQLREGREQNQEQLADIAAH
KPH
>A0A2V5QF46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIMDIMRGDLPTFSFEFFPPRTPEAAENLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIKAILVRYARSAIGNILALGGDRPRDIPYDKSR
DSFQHAVDLVKFIRRFNESGEHPDSRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYIVTQLFFDNHDFLDFRERCALAGIHIPIIAGIMPITSMSGFKRIAELAGGARFPAKVL
RALQRCENDPEMVRRVGVHFALEQCSDLLDNKVVGIHFYPLNRSDATRVIFDSLGIPHRR
SAQAPTV
>A0A4Y8UGE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium LSUCC0057|TrEMBL
MTQKDAVPLSFEFFPPKTDQGHANLAETRSQLAAFNPEYFSVTYGAGGSTRDTTRNVVNN
LIAAGSRAAPHLSFGGDGEATIAALLADYAAAGVEHIVALRGDLPSGMGGASQLVHANQL
VEFIRRECGDQFNILVAAYPEIHPEAESYSRDIYWLGEKFKAGADAAITQYFYNADAYFA
FVDACAKAGIDQPIVPGIMPLTNYQNLLRFSESCGADIPRWLRWQLKERADNSDDLLEYG
LEVVTKLCEQLIAGGAPGLHFYTMNQWRPTSRLCRNLLGASD
>T5HJB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus licheniformis CG-B52|TrEMBL
MGFLEDIKNKTLIADGAMGTLLYSYGIDRCFEELNISKPEEIRRVHEAYVQAGADIIQTN
TYGANFIKLSRYGLEDETKQINEKAVRLARAAAGSAYVLGTLGGIRTFNKNSYSLEDIKR
SFREQLYLLLNEQPDGLLLETYYDLEEAREVLKIARKETELPIILNVSMHEEGVLQDGTP
LADGLKQLASLGADVVGINCRLGPYHMIRALEEVPLLEDAYLSVYPNSSLPSLVEGRLVY
ETDDEYFRESAEEFRNQGARIIGGCCGTTPNHIRAMAEAVKGLPPVTEKRVKIRKKAALA
VQNERTEPALDDLAKQKRSIIVELDPPKQLNFEKFLHAAEELKSAGIDALTLADNSLATP
RISNVACGALLKQRLDMRSLIHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRLE
KKIACGADYFISQPVYSEEQLIKIHEETRHLETPIYIGVMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGNDKQKQAEEGLAIARSLLDAACDLFNGIYLITPFLRSDLTAELTAYIH
QKEKEKTNV
>A0A8J7UDS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Homeothermus sp|TrEMBL
MKVTDLIKANGKTGFSFEVLPPLKGKGISQLFRNIDILKEFKPLYINITTHRSEMVYKNT
PDGLYQKVSERSRPGTVAVAAAIQQKYGIPAVPHIICSGFSRIETEYALIDLNFLGITNL
LILRGDKAKHENRFIPNDNGYSHATELQLQINEFNRGYFIDGTKMDIVTGEPFSYGVAGY
PEKHEEAPNIDIDIQYARQKVDNGAEYIVTQMFFDNKKYYDFVDRCRRAGINVPIIAGLK
PITTMSQLNLLPKVFHVDLPMELATELMKCHTDAEAKQVGVEWCRMQAADLIAHNIPSIH
FYSLNATRSVEQVARDVY
>A0A7W3KNR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter ciceronei|TrEMBL
MTPPRPRQTDEHPDGIDLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSTSLLETVRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPYDFRPVHLGKKIAAGAQFVQSQYCFDVPMFRTFMNRVRDLGYDEKCY
ILVGVGPLASAKTAKWIRANVPGIHIPDTVIKRLEGAQDQKKEGKQLCIDIINEVKEIPG
VSGVHVMAYRQEEYVAEIVDESGVLKGRRPWKREARADDQRVAERLEHILHDDVTESQVD
MVKTAH
>A0A7S7RQ75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfurimonas marisnigri|TrEMBL
MFDELINKLKNDTYITLETTPGHSPVFTPTVDKIAELELDKLVDGFTTTDNPLAKLKYNA
LFAAKILQDRFNKPVIATMSMRDRNKIALQSDLLGANEVDIRAILALTGDPATISDQPHA
KGVFEGDSSLLLDIISCFNSGINYAGKPLTVKPKTLYPFAVVNSYAKNPKTLQKKIQKKI
KHGAIGIITQPVYDIENALQLLELRDAANAECCSEDKKGELIIGLFPITKLRTAQFLSAH
VPGINVPGSWLEALREANLEGAQEEYRVGFELSKKLFDDVKKLHPKIHLMTANQFQLARD
ILI
>A0A7U8BPR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter fetus|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEIASLIQEE
YQIPSIVHLPCIHSSKEKIIQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A6N7LBC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium terangae|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNAKFLSGRKLTTPPHVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSVITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWRRESLPSDAMVAERLEHLREGVEEDQQKMAEAAAH
HPH
>A0A2T2XYP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyvera genomosp. 2|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A328BPR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter edaphi|TrEMBL
MKVTEHLARATGRTLFSFEVLPPKKGENIQTLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFVAEPDGHAYACDLIGQVSDLNKGAYLDEEQDDTWATNFCIGTAGY
PEKHFEAPSHAADLRYLKHKVDRGADYIVTQMFFDNEQFFSFEKRCREAGINVPIIPGLK
PITTKAQLTALPRSFFLNLPDELVDAIHLAPDNAAAREIGIEWCINQSRELMAHGVPVLH
YYSMGKAESVRRVAAALF
>X6KQU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L103C105A0|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPLVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A4Z0J0E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. S111|TrEMBL
MTGKDVEKLREAAPAIPPGTRVNVTFLGNEELAMRVNAAKVVRELGFVPVPHISARRLKS
PAELEDFLGELQQVGASERVFVVAGDPKEPEGPYADSLSVIDTGILPNYGVTEVGIAGYP
EGHPDIATNDLWSHMEAKTQSLKAQGLDRVVLTQFAFDADRVCTWIRETREHGIDSLIRI
GTPGPAGIKRLLGYAGRFGVGTSASIVKKYGFSLTNLLGTAGPDRFLTELAGEIDDPSRN
DGPHRSNIKVHFYTFGGLLNTAQWVSDFSPGL
>A0A5L4WUT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter fetus|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A4R6DTH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buttiauxella sp. JUb87|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNYKQAHKFATMTNVRVPHWMAQMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPTI
>A0A069E7M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas adhaerens MHS-3|TrEMBL
MANRLWDTVQRLEPMAPDFVSVTYGAGGSTRERTHETVKRIAQETSLKPAGHLTCVSATK
EEVLAVAEEYWQAGVKHIVALRGDPPAGMGAAFDVYPGGFRDAVDLVKGLREHRPELGKC
FEISVSCYPELHPESRGWDAEIAYLKAKQDAGADRAITQFFFEPETYLRFLDKARAGGVT
MPIVPGIMLQANFRGLQRISGLCGATIPDWLSDLYDGLDDDVETRELVTANVAADLCRKL
AEQGVQNFHFYTLNRAGLALSTCRLLGLKPRSAKAA
>A0A3F2UVW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia seriolae|TrEMBL
MSFDNVRGYSTPGRVSRTPRVSGTRSVVQQLGPRPDGSIPFSVEFNPPRDAAGEARLWRA
AREFERLHPAFVSMTYGAGGSTRDRTIRITGQLARETTLLTVAHLTAVDHSVAELRSIVG
AYADSGIRNLLVLRGDPPGDVLGEWVKHPEGVEYAEDLVRMVRELGDFHVGVASFPQGHP
RSANLEDDTNFLVAKLRAGAEYSITQMFFDPEHYLRLRDRAIACDPVEGAKPIIPELMPI
TSLRTVERAVELCGRPLPPKVMERLHKAAGDGPEENRAAVREVGIEIATEIAERLIAEGA
PCLHFITLNFAKATGEVLANLGYSMSPAPATV
>A0A1Q3LY82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 61-13|TrEMBL
MSQFRFSRRPDIGDKIRVSFEFFPPKTDEMEARLWETVKRLEPLRPNFVSVTYGAGGSTR
ERTARTVARILGETSLSPAAHLTCIDASREEADNVIRQFASLGITRFVALRGDPAAGAGT
RYQPHPDGYANGAEMVGALKRHGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDIYERYVERVRRAGIYIPIVPGILPVHNIAQVASFSGRAGAHVPAWLRERFE
GLESDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRSDLAFAVCHMIGIRSHKPEAS
PNSAAA
>A0A396HLQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Medicago truncatula|TrEMBL
MPVDKIDHALETIKSNEIQNVLALRGDPPHGQEKFVQTGGGFACARDLMHGRDMKRDLV
>A0A0H3GGT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes serotype 1/2a (strain 10403S)|TrEMBL
MSHPEDIVAIHKAYIGAGADIIQTNTYGANYIKLARYGLEDEVKRINQAAIRLAKEAARG
TGTYIFGTIGGINGAVDARLPAAPLEEIKRSFREQLYCFLLDGVDAILLETYYDLDELKT
VLKILRETTDLPVVANVSMHEPGILQNGKKLPDALEELIALGADVVGINCRLGPYHMARA
LETVPLYDNAYLAVYPNASLPEMQEGKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTP
DHIRALRKGLETTKPILEKEVRPILELVPEEVEDVDSGERLLDKVKERLTILVELDPPRT
FDTTKFFEGAQALDEAGVDAITISDNSLATPRISNMALASILKHEYGIKPLIHLTTRDHN
LVGMHSHVMGFHKLGLHDVLAITGDPTKVGDFPGASSVFDLRSVELVQLIKKFNEGISYT
GKSLKEKARFHVGAAFNPNVLNLEKAVRLIERKVEYGADYIITQPIYDVNKAILLKEALQ
KANIDVPLFIGVMPLLSSRNAEFLHNEVPGIRLTDDVRERMREAEEHGHANEEGMAIARE
LVDAICEHFQGIYIITPFLRYDLSIELAKYAQNKQQVQIGSK
>A0A154QGQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter thiooxydans|TrEMBL
MPAISFEFFPPKTDEQRAQLDRAAQVLKAHGPEYASVTFGAGGSTLSYTGDTVARLHTQH
GFNVAPHLSCMGGTRAEIAALLDGYRAAGYRRIVALRGDMPSGMASAGDFRYAAELVGFI
REYCGDHFHIEVAAYPETHPQADDALRDLMHFKAKIDAGANGAITQYFFNPDAYFRFIDD
VHRLGVEVPIVPGIMPIANFSQLKRFSDLCGAEIPRWIAKRMQAHGDDADSVRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRAKATQAVLQQLS
>A0A178VYZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabidopsis thaliana|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFDCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIGENGLASNEAYQSDLEYLK
KKIDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYRGFLRMTGFCKTK
IPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKMLAHGVKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLVKVNSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLD
AVVEKCKALPSITYMAVNKGEQWVSNTVQADVNAVTWGVFPAKEIIQPTIVDPASFNVWK
DEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIFAVFADL
>A0A7S4N970|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odontella aurita|TrEMBL
MPPDPKIIDLISDNADGTSFTSLEFFPPRTEEGVKNLHGRMDRMLKNTKPLFTDVTWGAG
GSTAELSLRLALYAHDNGHVANMHLTCTNMTKNGDPVAAVRGALQEAHDGGIRNIVALRG
DPAAGETEWEAAEGGFTCALDLVRFIRKEFGDSFGVSVAGYPEGHPNAITELKPGEEADM
SEAEKGRCSTFDGVTCVCKDEDYKKEMDYLKEKVDAGADFIITQMFFDAAVYKTFVADCR
KWGIACPVVPGLMCINAYPGFTKMTKFCKTRVTKDLRDKMESLKDDVAAIKAFGVQFGTE
LCRDLTEAGAPVLHFYTLNLEKVVYGILDNLNDGTGDLNGKVNESDAAMQQAVGSAWARE
GDTVKTPFGKGTMKEVRRSGCGVIEFDDWVMAEGQRPKAYLRQDSYEKAM
>A0A2E0GH47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MQNLFQNTANFDIDHDSVLSVLKAAGEPTRLRLLNLINESELKVSDLTSILGQSQPRVSR
HLKLLCDAGLIQRFQEGTSVFYRGLPSGPYADFVKSINALSQGVYSFNSDFTKLEKLKXL
XAIQAERYFXXIAKRWNEIRSLHVPELEVXENLLKLFSDKKFRNFLDIGTGTGRILELIS
PIVXTALGIDTSREMXSIARANIEKKNLKNCYARLADMYNLPIENNSMDAVIXHQVXHFS
ESPLNVLKEASRVLQKXGMLVLVDFLXHDVEILRXXHAHLRLGFSXQEINEWFLDSXXXF
LPPKHLNGDPXTVCXWVGEKKXMSKLNXIKPIIXRDITGQKPGVSFEFFPPKTTEMEEIL
WSSINRLSYFKSNFVSVTYGAGGSTRERTHKTIEKIIQNTDLIPAAHLTCVGADKSSIXE
VAXSXWXLGVRKIVALRGDPPEKNQKYAPHPQGYLNAADLVNGLKKVANFEXLVACYPEI
HTDSKNFDDDXDNLKRKIDXGASCAITQLFFDDEVYXRWIEKVRTAGINIPIIPGIMPIT
NFXSTLXFCKMCGASIPDWLKSLFQGLDNDQXTRKLIGAVVAAEXCRRLQAEGISDFHFY
TLNRADLTYAICHILGXTQDSGD
>A0A7X3KT08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas otitidis|TrEMBL
MSQDRRYSFEFFPAKTEAGHEKLLATARTFAGYKPDFFSCTYGAGGSTRDRTLQTVLQLD
GEIQVPTAPHLSCVGDSKAELRALLAHYKDAGIQRIVALRGDLPSGMGMASGELRHANDL
VEFIRAETGDHFHIEVAAYPEVHPQARNFEEDLKHFVNKVKAGADSAITQYFFNADSYFY
FVDRVRQQGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYADDTASIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1G2XER5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium GWC2_45_44|TrEMBL
MAVTKKRLSKALKEKNGFAVVAELVGGANFNYAPIKKFLAAHSQAGGKDIPSEFNFVGIT
NPQSPGGVANIEPADVHRFAVANNLLGELDFIPHISCKDSNKDGIISLLAAHKAAGVESF
LALTGDKPATSKGVFELESVGLLNLTSYMNDEAVIKAKPDTLNSVPKFFAGAAVSPFKYN
EESQMQQYFKMEKKISSGAEFLITQVGWDWKKSVELMKYLADAKINVPVIGNVYLLSTIT
PAPRLMHDIKLPGCFVSDELFAKVCSESVDEHIERAAQQIAMYKSIGAAGVDIGGVHDYE
MFVKLLKRAAQIGDNWQQFKDNLCWPAKKAFYLYDDAGKRVELSKTKKTFGHRVFNCFHA
AILDPQYKGFHWLKKIMKFLGADKGKGFCYKSFNTFEKSSKYLMFDCEECGDCFLPENFG
LCTIGGCEKGMDNAPCGDSTAEGKCGNNLDRICIGDRIYKAAAAEKAGLEKLRKIINKPR
NPALEHTASILNYLFGKDHTLRSPLIGIAELVHASIPKTGEIMAKLHSLGDDWDTKPSGE
LDYIKALIESQATDGADYIAVNIDQFGESNPAFAVELMKKYVMLVRKYGKGVPVCIDSSS
DDVLKAGLKQWYDTNENVKPPLINSIKVYTIENMMPLKKHFDYKFIGLLISEGKSGSIIE
TESVDDLHNLAKTIFAAAKKYGFKAEEIFFDSTVFPLAIDMPMMPGTASYTHRTFNTIKR
IKTDPILKGCHFSLGVTNSVRDLPGRKIGVARAYVEVAMRFGLDAGIINVSHQFGVKPAD
ADLVKLVEAFANMDGSNEKQNEAMMLMGDFCSKNRKASV
>A0A6S5RES0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas otitidis|TrEMBL
MSQDRRYSFEFFPAKTEAGHEKLLATARTFAGYKPDFFSCTYGAGGSTRDRTLQTVLQLD
GEIQVPTAPHLSCVGDSKAELRALLAHYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VEFIRAETGDHFHIEVAAYPEVHPQARNFEEDLKHFVNKVKAGADSAITQYFFNADSYFY
FVDRARQQGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYADDTASIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A522AG56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MKLAIADQGAPAFDLVRSFSLEITAKDVESLFDAAPLIPNGTPISVTYLPSEDMDSRVTA
ARAAKSLGFTPMPHISARRIPSRNDLAGFLAALDEHVGIERAFVIAGDPATPMGPYEDAL
AVIRSGLLDGHGIRTIGISGYPEGHPEISDSKLMKAMKDKLEALAERDKAAEIMTQFAFD
SDAILAWLERIRQEGIIAPVRIGVPGPASVTKLIRFAARCGVGASTKVLLKYGASITRLL
STAGPERLIDTLAERLDTSRHGEIMLHFYPFGALVDTARLIDDRYGTNLA
>A0A4P6HAQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. Pch-S|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKTDEMETRLWETVKRLEPLRPNFVSVTYGAGGSTR
ERTARTVRRILNETSIPAAAHLTCVGATREEVDAVIRDYSATGIKRFVALRGDPASGVGQ
AYTPHPGGYQNGAELVAGLKAIADFDISVAAYPEKHPESPDFATDIEMLKRKVDNGAKRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHNFRQVANFASRAGAHVPAWLAERFE
GLDNDPQTHMLVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRAHQTAPE
VPENQPKTGSAAA
>A0A2A4U6Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSTTSRSAPSELPIAAPLPRDAEVSFEFFPPKSEKMEAKLWDCVERLAPLKPKYVSVTYG
AGGSTRERTHTTVTRIREETDIAPAAHLTCVGATREEIDDIARNYWEHGIKHIVALRGDP
VDGIGTDYEPHPGGYAYAEDLVKGLKDIADFEISVAGYPEKHPQAQSLDADIEFLKRKVD
AGADRVITQSFFDNNKFLEFVDKARSAGIEVPIVPGILPVTNFKRVQEFSTQTGTSVPGW
MAEIFEGLEDDMETRKLVAATVVAEQCRVLYANGIKEFHFYTLNRADLTYAICHILGVRP
>G8BIZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida parapsilosis (strain CDC 317 / ATCC MYA-4646)|TrEMBL
MSKVKDLIQSLGPDEKFVSFEFFPPKTDSGFRNLLARLNRLSAFNPLFITVTWGAGGSTS
EKSLDLAATCQKKIGATTVLHLTCTNTNKEVIDAALKRAKANGIRNILALRGDPPRTEEY
WTPNCQFKNAVDLVKYIRSEYGDYFCIGVAAYPEGHVDGADVSNQNPRKDIPFLIEKVKA
GADFIITQLFFDVDKFITFEKLIRQSPELKNVPLIPGLMPITTHRVFTRATKLSHATIPT
KIYKQFEEIKNDDDAVKSVGVDLLCDIINKIDESTAIKGYHFYTLNLEKAVASILNKSTV
LHPILERPSPVFGNEDAIASDSDSDDEIAVPPQQQKRRKSSVVEPLTQKAVVEISRGLGA
LGKEAIWDDFPNGRFGDSNSPAYGEIDGYGPNLKIYDKSEAIAKWGSPESISDLSHIFTS
YLSGKIDVIPWADVPLSPETALIQEELFELNEKGWFSVASQPSVNGCKSTDNIFGWGPPN
GIVYQKSFVELFMPAKDWEQLRSNLDDSTTFYVGTKSGEIKSNLPIEQDYSKSKSAVTWG
VFPQKEILQPTVIDYESFKAWNEEAFLLWLEWARCYKKNSKSFALLNSIYNDYVLVSLVH
HDFPNEDALWRLLLQ
>A0A1H0BX78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus siccatus|TrEMBL
MSVESPGRPRAPRGTGSPPTVGGRPTRRRSPGALERALREASYEVLPLRGAEESVVEHVP
RTVPLTVTVTEAKGLTPTLELAERLSRHGFTATPHLAARLVRDRAHLADVVARLRAAGVD
GVFVIGGDAAEPAGRFPDALSLLEELETVGHHFRQVGIGGYPEGHGHISAELIERALERK
APHATHVITQLCFHAGTTTAWARQVGLRGVDLPIRIGLPGAVTRQKLVRISAGIGLGQSA
RFLRKQHSLFWRFFLPHGYRPDRLVERLVPALGRPEHNLQGFHFFTFNEVARTEAWRREW
LARLSDADPR
>A0A2E8YEE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichales bacterium|TrEMBL
MDAGVDASAVPSMGHFEQVLRSGKFAVTAELSPPDSADPEEVYARARVFDGYVDAMNATD
GSGANCHMSSVGVCALLTRLGYATVMQMSCRDRNRLAMQGDLLGAAAMGVANVLCLTGDG
VQAGDQPEAKPVFDLDCISLLTTIRQMRDESRLLSGRRLSSPPRVFLGAAANPFMLPLEF
RPTRLAKKVAAGAQFVQTQYCFDIERLRNYMRQVVDTGLHEKCFVLVGVGPLVSAKSGVW
IRDNVPGVHIPDQIIDRLRRSDKPKQEGKRICMELIQQAHDVEGVSGVHVMAYRQEEAVA
EIIDASGVLEGRTAWYPGVNVVNELDKRAV
>A0A2D7CRF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSASLKQISSLLNGFSTEVTPTSASKIDNFQDHLSLGTSINVTFLAGSNLRDTVQVCKRL
NEEGFNPVPHIVARNFENTMALEIFLDLLVSTADVHEVLVIAGGIGRPLGPFSDSLQILN
SGLLEKYQIRKVGVAGHPEGSPDISKDKLANAIRDKNNWAKNSDMEAYITTQFCFEVPSI
MTWEKNIRRDGNKLPIHIGIPGPATLNTLIKFATMSGIGPSIRVLTRQTKNLTKLVFTQD
PLRIIEGIAFAKLQDPDCLVEQLHFYPFGGLAKTAAWIKDILEKSEFKNLEVG
>A0A352X3G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium UBA11367|TrEMBL
MTSYNTFRNAVKSGEFLITAEVAPPKGGDPSHTIAMAQTLKGRVHAVNITDGSRAVLRMS
SLAASVILLQKGIEPICQMACRDRNRIGLQADLMGAHALGIRNILALTGDPVKAGDYPDA
KSVFDVESVRLLQLIGRLNRGLDGNDKPLPDGNTDLFPGAAVDPQLASWSGLQRRFERKL
EAGAEFFQSQLITDFERLEVFMDKIAAGIDKPILAGIFLLKSAKNAEFINKNVPGVSIPQ
FIIDRLAGATDPLGEGMKIAAQQVRLAKELCQGVHIMAVKREDLIPQILDLAGIAPINVV
SD
>A0A5C7NUP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MNQDLPPHWDPGAPLPQKAGHSSQGRLERVLRSGRFAVTAELNPPDSADPREVYERALVL
SEVCDAINATDASGANVHMSSVGICSLLTRAGYAVIMQISCRDRNRIAIQGDVLGASAMG
VQNILCLTGDGVQAGDQPQAKPVFDFDSTSLLECIRGMRDKGQFLSGRKITTPPRVFLGA
AANPFAPPYEYRGVHIAKKINAGAQFIQTQYCYDVPLLKSFMAQVREQGLHEKAFFLVGV
GPLPSAKTARWMRSNVPGVHIPDAVIERVEKAKDQKAEGKRLCVDLIQEISEIEGVAGVH
VMAYRQEEYVSEIIQASDIMKNRQPRRAPRPAPETEPAGAVNETITAA
>A0A2A9FXI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. ES.051|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSAKMEETLWNSVLRLQTLQPKFVSVTY
GANSGERDRTHSIIKEIKATTGLVAAPHLTCIDATRDELIDIADDYWNNGIENIVALRGD
IPLGGGAPEMYASDLVALLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRP
>W9R4J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morus notabilis|TrEMBL
MKVIEKIRENQNKEAVFSFEFFPPKTEDGVENLFERMERMVAHGPTFCDITWGAGGSTAD
LTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALSTIKSNGLQNVLALRGDPPHGQDKF
VQIQDGFACALDLVKHIRATYGDYFGITVAGYPEAHPDAIGSDGVATPEAYEKDLAYLKS
KARSFLPISLFDVHHHAKIPAEITAALEPIKDNDEAVRAYGIHLGTEVCKKILAHGIRTL
HLYTLNMEKSALAILTNLGLIEESKIPRSLPWRRPANVFRVKEDVRPIFWANRPKSYISR
TIGWDQYPHGRWGDSRNPSYGALADYQFMRPRSRDKKLTEEWATPLKIVEDIHEKFKKLC
LGKLKSSPWSELDGLQLETKIINEQLGKINTKGFLTINSQPAVNGEKSDSPSVGWGGPGG
YVYQKAYLEFFCSKEKLEALVEKCKGFPSVTYVAVDREGAWRSNIEQTAVNAVTWGVFPA
KEIIQPTVVDPSSFVVWKDEAFEIWSRGWARLYPEGDPSRKLLEEVCDFGFVYVHNILVI
FDDVSRDVCGPLLQVQTSYFLVSLVDNDYVQGDIFAVFADL
>A0A1V3RC35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. A49|TrEMBL
MTAQTLYPAERGNLRLSFEYFPPKTDEMEAQLFQTAEELSVFCPAFVTVTYGAGGSTKTR
SLTTVKRMIEEKGFANTAAHLTCVGAPRSEVDTVIDEFLAFGVRHFVALRGDPQGGIGST
YAPFPGGYESSSDLVRALRDRGDVEISVSSYPEKHPESPDVDADIDMLKRKVDAGATRAL
TQFFFDNDDFERYLERVRRAGIDIPIVPGILPINNLSQVQKFAGLCGASVPEVIVTRLAH
LEDQPTERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFERADEMAQD
EQVALKAVAGAAA
>A0A1F4B9I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_65_24|TrEMBL
MERQPNRIPPVSFEFFPPKTPEGVKKLRATWTALACLGPRFFSVTYGAGGSTRDRTLGTV
LEIREAGHEAAPHVSCIGLTRAEIADTLELYRLKNIRHIVALRGDLPSGTAALGELRYAA
ELVAFIRERTGPQFRIEVACYPEFHPQAESPRADLLHFLDKVRAGADGAITQYFYNPDSY
FRFVEDCQAEGVAIPIVPGIMPIGNFTQLVRFSDACGAEIPRWLRLKMDNFSGDLNAVKA
YGLDVVTAMCDRLITQGAPGLHFYTMNR
>A0A378GXD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria rosea|TrEMBL
MTPRPTARPAPPSLSYELYPPRSAASADTLLRTIEELEPTRPDHVSVTYSGDEQRRDSSL
ALLDHLLARTSLRPLAHLTCVGSTRAELEQTVAALVRRGVRGVLALRGDLDPGAEPGELR
HAGELVELVREVEQRHTAALAAGRLAVGVAAYPTRHPESPSFRHDVEVLLAKQRSGADFA
ITQVYFRPQRYERLVAAARAAGVTIPIVPGIMPVTDPRRLRTLCRLAGLAPHPGLAAALE
DAPGPAERHRAGVAFAARLARAALDAGAPGLHLYTFNEHRAALDLLEHVDLPRVPHVPVA
LEDLLLPA
>A0A8C1BDL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MSCEQYQNMLYSGYSDVGWQSSKSDSSGVSNSGESSKESSRCSTPVQDADRTDRLRDKMK
RRIESGDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSM
MIASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGGMNGDFDGDFFC
VNLVTFRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAF
GELTDYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWND
DPLAPETNLLKDELEKVNCRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFT
SSENVTALLQVLKKYEPRVNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDP
VSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLINLVDNDFPLDSCLWQVIE
DMFTLLDSPPETQEEGSQS
>A0A2N5MJG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. V5-8f|TrEMBL
MDFRDELRTRILIGDGAMGTLLYSNGIDNCYEELNISHPDRIATIHTAYLEAGADILQSN
TYGANYYKLKLYGREEEVSSINRKGISLAKKAAMGKAFVFGTIGATRSFRKSNLELEEIK
RSFREQLYSQLMEDPDGLLFETYYDLEELETVLKIARQETQLPIIANVSLHEIGYLQSGI
HLNEAFLRLEELGADAVGVNCRLGPHHMLRSFEEVPLPKHAYLSVYPNASLPDYIDGRLV
YEAVPEYFGSSALKLREQGARIIGGCCGTTPKHIQAIKQAVGNLPPINEKQIKPRKMELI
EVTYNENNVALHQKAKKERTILVELDPPKKLGIKEFMAGAKALHDAGIDSITLADNSLAT
PRISNLALGTMLKNEIGTEPLIHITCRDRNLIGLQSHLMGLQTLGLNEILVVTGDPSKIG
DFPGATSVYDLSSLDLISLIKQFNEGLSYSGQSLGQRTNFKIAAAFNPNVRYLHKAVERM
EKKIACGAHSFLTQPVYSVSQIEDLYESTKHLDTPIFIGIMPLTSSRNAEFIHNEVPGIK
LPDDIRKAMAAAGSDPVKARAEGVAIARELVDAAVEKFNGIYLITPFLRYEMTVELSIYI
RKVDSERFVEVTTYEQ
>A0A8C1BCT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
GPVLSRGTACPGRSSKSDSSGVSNSGESSKESSRCSTPVQDADRTDRLRDKMKRRIESGD
HWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGGMNGDFDGDFFCVNLVTFR
RPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYY
LFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPET
NLLKDELEKVNCRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTA
LLQVLKKYEPRVNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWK
DEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLINLVDNDFPLDSCLWQVIEDMFTLLD
SPPETQEEGSQS
>A0A7C5EHL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MCMPVELEQPERNNAMDNLVEVLTPKQDSQDLDKDLETFATKYRRALDEGFGLSLPDNPM
GRLHFQATEVLPELGLPVPPGKALLHLNTFHTKEHLDGILKTAGEIGITHILVVSGDGSE
RLPKLKPEDIGMSVNSVTSVELIQYINARHPNAFTLGVAFNPYEPLDHEIHKMERKIAAG
ARFIITQPIIERHQALEELRRFNTPVMLEAWMSKRIDLLAQCIGYDLPQNQAYDPLQNLR
TLRANYPDSKMYLALVGFKTQIPEIKNILGMQ
>A0A7H9HZT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Torulaspora sp. CBS 2947|TrEMBL
MRITEKLQKQKQKSSKPTFSYEYFVPKTTQGVQNLYDRMDRMYESSLPQFIDITWNAGGG
VLSRLSTELVSTAQSVLGLETCMHLTCTNMPVSQIDDALQSAYDSGCQNILALRGDPPVN
TEWAPVEGGFKYAKDLVKYIRSKYGDHFDIGVAGYPEGHPGDDTDGSELIDYLKQKVDAG
ASFIITQMFYDAEVFIDWCKKVREAGIDIPIIPGIMPITTYAAFLRRAQWCDIRIPDEFM
KQLEPIKDDDQLVRETGTNLVVDMCQRILDSGYVTHLHLYTMNLERAPLMILERMNLLPD
QEHLDGENTLAMLPWRKSLNPQRRNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGDS
SSPAFGDLDLCGSSLIRQSGKKSLELWSTPKTVEDVAQLVVNFLQRKVSYLPWSDMPLNH
EVDAILDDLIQLNKKHIITINSQTQLNGVKSSDPVFGWGPKDGYVYQKQYLEFLLPKSKA
QRLHDALKDDVILTYFAVDDEGNLLTNHPDGCRANSVTWGIFPGREVLQPTIVEKVSFLA
WKEEFFHILKEWRLNFQNHQIQESVDLLTHLISDYVLVNIVDNDFISQENKIFALLNKIS
D
>A0A8C2KZR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGKDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIITQLFFRAETFLKF
VKDCRAIGISCPIVPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNCRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTES
>A0A7X8J7T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MSDLLKEKLDKRVLIFDGAIGTELYKRDFFVNTSYEGLVLTNPEQVKEIHRNYIDAGADV
LTANTYGANRNKLRRFGLGDKVVEINRVAVELARQCCGTENLIGGSVGQIGESSYGHPIS
DELAQEIIQEQIGALKEASVDFIIFESLSTEKAVTDALTAIAGFPKLPYLISLTGPREPD
AGNQFWANIMSQIKAAPHQPTAVGLNCGTGAEGMLSALESLLPLCPYPIVVQPNAGMPKS
VDNRMIYMCSPEYLTTYAVRYVNLGARGVGGCCGTGPEHIRDIARSIRPLAKSMAKTTIE
LSEPQLPTVEPVPLEQRSKLAAKLVRGEWVTTIEVTPPRGFALGDVIEKAVQCRNAGVDA
MNIPDGPRASSRISPLITAIEIQEKAGLEVILHFCCRDKNLIGMQADLLGCACKKINNIL
FITGDPPKLGDYPFASAVFDVDSIGILKVQSRLNQGVDIGGKPIGAPTSFCGGAGADPNS
LDMKRELLRLRQKVEAGAEFIITQPVFSSESLLEMLEKMSDLKVPVIAGIWPLASYRNAE
FMKNEVPGVVVPDEVMTRMAKADSKEEQRQVGIAIARESIAKIRHAVQGVQVSAPFGNVN
TALEVLK
>A0A264EJZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus odorifer|TrEMBL
MKPDLRSAWGNKVLVGDGAMGTYLYQKGFPVGISYEELNLTSPGVIEDVHRSYIEAGAVL
LESNTFSANYDRLSKYGLESKVEEINRAGVRIARQAAGDHGYVLGAVGSIRAGKRANLSS
TELKKYFTQQIAALLEEDVDGIMLETFYDVEELHLALRTLRKISSLPVVCQLAVDETART
LDGLTLPEAFRILEGDGADVIGFNCNTGPNGMKRALKAVQGNLVLPASVYPNAGVADYVD
GEYRYGASPEYFGQMAQTFAEMGCRIIGGCCGTTPQHIAEISSALKNYVPQPLPKPLPPA
VERVSLQENFGDEDRDGREPNLVDLVKERHTVIVELDPPRELDIAKFMQGAEVLRRAGAD
ALTLADNSLAVTRMSNMALGHLVHAKTGLRPLVHIACRDRNLIGTQSHLMGFDALGIDHV
LAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGISFSGKPLKQKANFVIGAAFNPN
VKHLDKAVQRLEKKIASGADYIMTQPVYDQELIVKIAEATAHLEIPVFIGVMPLASGRNA
EFLHNEVPGIQLTDDVRDRMKGLEGEAGRAEGVAIAKELLDVATAHFNGIYLMTPFMFYD
MSAQLMEYVWEKSGRKLSPLFR
>A0A7Y8Q1Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. SwsAc6|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLADFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIKRFCEKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTDSIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVQDLGLA
>A0A3N0BVZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter oryzae|TrEMBL
MSPPSLIESHSTLSDAAPVALSYELFPPRSPAAAESLWTTIGELESTDPDYVSVTYGASG
SNRSTAVELIYRLVQETTLRPLAHLTCVGNSPQELAEIIAELLDVGVRGILALRGDMPKD
GGTPPEGSLRYAQDLIDLIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDIEVLL
AKQRSGADFAITQVFFHTGQYADLLTRARRAGVTIPIIPGVMPLTSIRRVTRLGELTGVE
PDTGLMDRLAAADSDAERARIGVGATVDLANAALDAGAPGIHLYTFNEHASALEVLDKLA
LPRPRRADRRPAGRRVSASGHQLAS
>I1ZNQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis FW213|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFAHQPNFEVN
>A0A1J3HDM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noccaea caerulescens|TrEMBL
LASPPLLFSHIPFRIWFLRSLRRMKVVDKIKSVIEEGKTAFSFEFFPPKTEEGVENLFER
IDRLVSYGPTFCDITWGAGGTTADLTLDIASEMQNVICVETMMHLTCTNMPVEKIDHALE
TIRSNGIQNVLALRGDPPHGQDKFVQVEGGFDCALDLVNHIRSKYGDYFGITVAGYPEAH
PDVIEANGLATPESYQSDLAYLKKKVDAGADLIVTQLFYDTDIFLKFLNDCRQIGINCPI
VPGIMPISNYKGFLRMAGFCKTKIPAELTAALEPIKDNEEAAKAFGIHFATEMCKKILAH
GITTLHLYTLNVDKSATAILMNLGLIDESKIYRSLPWRRPANVFRTKEDVRPIFWANRPK
SYISRTKAWNDFPQGRWGDSRSASYGTLSDYQFMRKRSRDKKLQQEWVVPLKSIQDVHEK
FKELCLGSLKSSPWSELNGLQPETKIINEQLGKINSNGFLTINSQPSVNAANSDSPAIGW
GGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFPCITYMAANKAEKWISNMSQSDVNAVTW
GVFPAKEILQPTTVDPASFKVWKEEAFEIWSRGWANLYPEDDASRKLLEEVKNSYYLVSL
VDNDYINGDIFSVFA
>A0A4U0ZW86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus sp. IMCC35007|TrEMBL
MDAAQDTTATRQKSRTLIAEIDPPKGVNLDSFLSTAQQIRGRVESVRITDCEHAIMRMSP
IAPCLALKDNGYEPEMVITGRDRNRISFQADLLSAAALGIKNIVIKEGNDPAEGDQPVVR
TSGDLDLVSMLECVSALNGGKDLGGEALDGATEFKIGVALDLSDDVNLNRARAEFFKPMQ
RYGVSSVTLGPTYDLNIIEPFLQFSEETGIELFASVMFLKSVTMVRYLNNLPGVPSIPQE
FLKKMINAPVKKDAGLQAAAELMTELATLTSGTVLLAMGGKDRLPEFLDLIGR
>A0A1M5SLN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. CF038|TrEMBL
MANHNFSIEFYPPKTPEGADKLRVARAKLAQLDPQYFSVTFGAGGSTQQGTLDTVLEIMS
EGHTAAPHLSCVGGSRESIRDILHQFQAHGIRRLVALRGDLPSGYGGGGEFRYASELVEF
IRAETGDWFHIEVAAYPETHPQARSPQDDLQSFARKVQAGADAAITQYFYNADAYFSFMD
QTAKLGIDVPVVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTQLCERLLAGGAPGLHFYSMNQAAPTTALWQRLVKA
>A0A2N2E464|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-10|TrEMBL
MHNPLDHIINKIYHVEILPPKQESTKLLADLDVFKEKYMRVMESGYCACITDNAMGLMAF
QGHEIIEEMKLPVHSDQVMIHLNTFHTKADLDNILLSCKNLGIESLLIITGDGSDRLPKL
QPKDIDESEVESVTSVELLRYIHRAYPDTFVLGVAFNPYEPPNHEFAKLSRKIEAGASFI
ITQPIIEQNPQVDRLLAEYPDIPVTVEAWMSKKLSLLSDAIGYKISEDTQFDPIATLKML
HQVYPQCGVYLSLVGFKTQYDLIKGLWI
>A0A2E5DPH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacteraceae bacterium|TrEMBL
MDNKEIINLKKLINNYTIETTPKNFEKISDLNNLLPKNTSIYITYLPNENYKKIIDTAKK
IKDEGFEPIPHLPARTIKNFSEVEKYLGMLSEISGAKKILIIGGSSYQNGNISSSMEILE
TGLIDKFNFTEVGLAGHPEGSPDISDEELDRAIIEKNKFVSNTQAKLYFVTQFFFETSSF
ITWEKHLEELGNKIDIHAGLPGPANILTLINFAKSCGIRNSINFLSKQALKISKLASTKA
PGKLVYELSKYKNSNSNSKLTKLHFYPFGGMKKTSRWIKALVDNEIRIDQNNDIEITNFD
L
>A0A6N7JR63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niveispirillum sp. SYP-B3756|TrEMBL
MSLPATDLSAPLITAPGDLTVSFEFFPPKTEKMHENLWAAIHRLAPLKPAFMSVTYGAGG
STRERTHATVTAIQDQTGIPAAAHLTCVAATKEEIDEIARAYWDAGIRHIVALRGDPPPR
ADGTGGLGGRGYEPHPGGYAYAADLVAGLKRIGDFDISVACFPEVHPEAPSAQVDLDNLK
RKVDAGANRAISQFFFDADAFLRFRDKTAAAGIDVPMVPGILPILNFKKAVEMGEKCNTA
IPGWMRDLFEGLDEAPETRHLVAATVAIEQCRYLARHGVKQFHFYTMNRADLTVAICHML
GVRARG
>A0A6M1NDV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. SGR-19|TrEMBL
MKIVDHIKNANGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYLYKQ
HVSGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTREETENALIDLNFLGIDN
VLVLRGDARKGDPDFVPTPGGHAYATDLLQQVVDMNNGKYLHEDIESSAKTDFCIGVAGY
PEKHFESPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PMTTKRQLITLPKIFHLDIPEELSEAVDNCKTNADVRQVGEEWLVEQCKELIKFGAPVLH
FYTMSNPGPTKKIVERLA
>A0A846NLU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrososphaeria archaeon|TrEMBL
MVIKRPAYSSLVKEIKKGNFVLTGELEPEKTTGLEEILASARAMKPYVIAANVTDNPLAM
AFMNSLVPSYIVQRDVGLETVYQMVIRDRNRLALTSDILAAAHLGIKNILAISGDHTALG
DNKGGLPVYDLDSAQFVYLLHKMIDEGTDLVGNEIHGKVPINVGIAANPNANPLEPEVLK
IERKTKIGVDFIQTQTMFDIDLTKEFLKETERLNCPTLIGIFPLKSFGIADFFDKYIPGV
HVPKDLLIAMEKCKDEPDKEKRKDLYDDVNMDFFGPFIKEIRKTTKAAGVHVMAVLYERI
FEPLLEETL
>A0A7X8F0A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSKNPLTDKLTRGIVIGDGAMGTQLYQHGAFLNTCFDELNLTRPDWIERIHSEYIEAGSD
FIETNTFGANPVKLVRFGLAEKCVAINTEAVRIARRAAANHEVMVAGAVGPLGLDNPLPT
AEQAEQSRAAFAAQCEALAAAGVDFFLFETFTDVAELLNAIEAAGRYPTIPIVAQLTCTE
HFETPFGTPIDQAIAQLSACEGVTAVGLNCSIGPSDMLEALKRIVGSTDKPISIQPNAGL
PRRVEGRTLYMCTPEYMAEYAKRFFEHGARIIGGCCGTTPEHIRQIVKAVRPLDRAVSPK
APGKVVVRQAVIEPAFEPIPLADKSRLGRKLAEHKPITCIELTPPRGVDLSRLLDNARLC
AEHGIDAINIPDGPRASARLSPLVTALKIEQTIGIETILHICCRDKNLIGLQSDLLGIHA
VGLRNVLLITGDPPKLGEYPDATGVFDLDSVALTQAAFNLNTGRDIAGNALPQPLALTLG
VGANPVASDLHREIDRFRLKVQAGAEYAITQPVFDTEMFFAFQASVEDCAIPFIAGIWPF
TSYKNAEFMANEVPGVVVPEALLQRMAKAKTAEDAKKIGIEIAHEMIATLAPHVAGFAVS
APFGNVRLALAALGRLHL
>A0A8D6NC94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. MAS-1|TrEMBL
MTHSADPHSAGRAPARPTVSLELFPPRPGRAAPATWSRIDSLLATAPDFVSVTYRPTFVT
DAAGQGAVGVRVVNEPNPAEQVVEHVLGTSTVPLMAHLTCIGYRRSDVVEIVTHFLGMGV
RRFLALRGDPPAGTAPDQVAGELPHADDLVRVIREVEAEYFGDGRRHVTVAVAAYPVTTD
HAQAIEVLAAKQAAGADLAITQVFYDAEDYAALCRAASYAGVTMPVLPGLIPLTDLGRLT
RLESLTGVPVPSGLRAALSSARGAELVGRGLDATLGLATDLLEAGAPGLHLYTFNRTRPA
LDIISHLRLGGILSGSAPDPRVREAIERGYLQATPGRGPSFLRGGHRRPPTGGTSPSGHH
HH
>A0A7V3MAK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTEQAPVSRLEKILTKGYFAVTGECGPPKGADRSVIERKAQYLKGTVDAVNITDCQTAVV
RMCSMAVAKILLDLGIEPTMQMTCRDRNRIAIQSDLLGAYALGVRNLLALTGDHQSFGNH
PEAKGVFDLDSIQLLQIVHRMGEEGVFANGEEIEGGPVRFFLGAAENPFADPFDFRPYRL
AKKVKAGARFIQTQLIYNVPKFAQFMQRVRDLGLDQKVYILAGVGPIKSYGAAKYMATKV
PGMDVPEEIVERMRKTPKEKQKEEGIKICVEIIQQVKEIPGVAGVHIMAIEWEEAVPQIV
EMAGLYPRPEV
>A0A7C4UUP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MNTSPQDRWVEKLGRQFVVNVEIVPPAGEKSDIGSRACSHLAGLPVDGLNIADSPMARAR
VTPLLVAHLVEQECPGRFAYVPHLNARDHNRVAARGMLWGAAAMGVRAVLIVSGDAISFS
NDPQARAVSDVHVPDLIGMAREAGLLAGVVLDPRPAQWETERRKMVRKVEAGAGFVITQP
LFEPAHLERVAEQMEPFHLPLIAGILPLVSVRHARFLDQRVPGISVPAPLIAELERAGPE
ALAVGLENARQMLECARRVCAGACIMPPFERFELVPAILS
>A0A7V2PP43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTTPRQRFLDLITRAERPILLDGAMGTMLHAKGIGFDQCFDALNLENPALVAEVHRGYIE
AGAQVILTNTFGANRYRLAEHGLEDKVAAINRAGVELARRVVLASFREVLVAGDVGPLGV
RLAPFGRVQPEEARAAFREQMAVLAEAGADLIVIETMSDLYEVREAVLAAREVAPDLPIV
TSVTFTRDDRTLLGDAPEKVAETLRDLEVDVIGVNCSGGPAQLLRILKHMRAVAPEARFW
VKPNAGWPERLPGGRIMYPAGPAYFGEYALAFYQAGATLVGGCCGTTPEHIAAMHHSLEQ
APPREALPRLTVSLSQRREQLPPPDEPTQLAQKLQHGQFVITVEMTPPRGLSAHKVLAGA
HLLAEAGADTINVADSPMARMRMSPWAVCHLIQREVGVETVLHFPTRGRNLLRVQGDLLA
AHALGVRNVFVVMGDPTAIGDYPEAMDNYDLVPSGLIKLIKQKFNAGVDHAGSDIGQPTS
FFVGCALNLNPKDPEREARVLRRKIRAGADFALTQPVYDPEAARRFLDFYAERYGPVEIP
ILVGVLPLNNPRHAAFLHHEVPGITISEPIMRRLEQAGERAPWEGVRIALELIERIRSWA
QGVYLMPQFRRYDLVAEIVEGVRARTEQG
>A0A846PZB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrososphaeria archaeon|TrEMBL
MTIRYEANPPKITPGVDLDESISKFIEKIKLISKNCDAIHLTENVLGFERVSPLKVGKII
KKEIPELPLTVSLRVRDKTQEEIDSFVQDAISSGFSGILVLMGDPSQAGQKDSGLIPSLV
VKQLYENKINEKIDLYLSISNKPNFSKIEKKLDAHPKGFMTQVVQNLEQVETLAENLKGY
LVIPIVLYPSDKNEDSAKFLNLDLAKYKDNFGEFLSKIEQITGDVLITSPRDFTSLKEFL
ETRG
>A0A399Z999|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MDFLKTLSSQTLLADGAMGTMLHVRGVGFDKCFDELNLSNPGAVAEIHREYIEAGAQLVI
TNTFGANRFKLTKHGLASQTADINRAGVELARRVVTDSARDVLVAGDVGPLGVRIAPFGR
VQPDLARAAFAEQISALADAGADLIVIETMTDLYEIKEAIRAARETRALPVVASVTFTRD
DRTILGDDPAKVARTLTEAGADVIGVNCSGGPAQLLRILKAMVAAVGADLGVRPSLGVHP
SLGVHPSPRVRPSLGVRPSPRVRPYFWVKPNAGWPEQVGGRIMYPADADYFGEYALSFRE
AGANVVGGCCGTTPAHIASMRRALDSAAAPAPLTAIPLPVEEEALEGAAAESELAQKLAA
GKFVVSVEMDPPRGLSTHKLIAGASLLADAGADVINVADSPMARMRMSAWAVCDVVQRQV
GVETTLHFPTRGRNLLRVQGDLLAAHALGIRNVFVVMGDPTAIGDYPEAMDNYDLVPSGL
IKLIKQGFNAGVDHSGTSIGQPTNFFVGAALNLCPPDLANEFKNLTRKAKAGADYFLTQP
IYRAEDGEEFLSKYEGRHGALNKPVLVGILPLVSVKHANFLNHEVPGISIPDEAIARLEA
AGEDAAKVGVELAVELIEKVKPWAQGIYVMPQFHRYDLVAEVVERVRG
>W7YXQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus pini JCM 16418|TrEMBL
MKPELRKAWDHQVLVGDGAMGTFLYQMGFPVGISYEELNLTSPEVIRDVHRRYVEAGTQI
LETNTFSANYDKLSKYGLESKVEEINRAGVRIAKEVAGPNGYVVGAIGSIRGGKRTNIST
SELKQYFEQQITALLTEGVDGILLETFYDVEELYLALSNVRRLSDLPVICQFAVEDLGRT
LDGYTMPEAFRLLQQEGADVIGFNCRTGPNGIMGALRTLEGQLSVPVSVYPNAGVADYVD
GEYRYGATPEYFGQMALKFADMGARIIGGCCGTTPAHIAEIASALKGYVPQPISYEPVPV
QPPVVIHEQLAEDTSVSKTPNIVDLVKQRHTVIVELDPPRDLDIVKFMKGAQALKDAGAD
ALTLADNSLAVTRMSNMALGHLVQAQTGLRPLVHIACRDRNLIGTQSHMMGFDALGIDHV
LAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGQPLKQKAKFVVGAAFNPH
GKHLHKAVARLERKIAAGADYIMTQPVYDPELICAMKEATKHLEIPIFVGIMPLASGRNA
EYLHNEVPGIQLSDDVRTVWLGSKELRAELWA
>A0A7W1G5F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRLDELFDARERTLSFEFFPPKNDRAWYTLEDTIDQLVQLGPDFISVTYGAGGGTRARTR
EVVEHIQAKTGVTAMAHLTCVNATKAELRALFDEYHGAGIQNLLALRGDPPKGEARFTPT
DGGCAFATDLIDLIRTDGRFAIVCAAFPEGHPDNPSRSADWDWLTRKFEKGAVAAITQCF
FDVAPYLELVDHLTQTTGRRQRIIPGILPITDFHALERFCARCGASIPDSVRALLAPLAD
DPLAVRQAGIAYTVGFCRALLAAGAPGLHIYALNRSTAAAEVVTALRLSGSLH
>A0A7C7QMD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTELKAGSNLEKILTAGHFAVTGELGPPQSADPEVIHKKASYLKGYVDSVNITDCQTAVV
RISSMSVAVILLGLGIEPNMQMTCRDRNRIAIQSDLLGASALGIKNLLCLTGDHQSFGNH
PTAKNVFDIDSMQLLQMVKEMRDEGKFLCGDPLKGEKPRFFIGAAANPFADPFDFRPLRL
AKKIKAGADFIQTQIVFNVPKFREFMKRAGDLGLLDKVYILAGVSPIKSLGAARYMATQV
PGMDVPEE
>A0A7C1JEH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPDYLSKYQQSLVAKDVFSITWELVPGRGAFEKAQAEVIASAELAAKGGKVHALTLTDNP
SGNPAISAEMLGAEVNRLGIEPLVHFTCKDKNRNELEALLHGLERAGVRNLLVMTGDYTY
TGHRGRAKPVFDLDATQLLGLIADMNKGLEVPTLRGTSTLVPTHFFAGAAVSPFKALEAE
QVTQYFKLKKKLEAGAQFIVTQLGYDARKFHEVLLIMKHLGYEHVPVVANLYVLTLPAAR
LMNKNGVPGCVVTDRLLAQLEEEAADKATAKEKRLERAARMYAWMKGMGFAGVHIGGHGL
KYEDVEFIISRGEELVPNWPDLVREFEYPMPGGWYYFEKDPKTGLNTETPVDRSGSRPGV
GLGYRCFRLLHQTMFEPKGVFFRPMSWLARAVDGSRLEHLFTRLEHIGKQVTNECLHCGD
CALFDVAYLCPMSQCPKGQRNGPCGGGYQGWCEVYPGERQCVWVRAYNRLKHYREEEEIA
SRQVPPPDWELYRTSSWLNYYLGRDHTAKRLGIKPPEKKAASG
>A0A7V3ACS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MLARLRFSEILAQAARPVFSFELFPPKTQAGLVRLIRILPGLDALHPDYMTVTYGAMGTT
RANTLEIASHIMYRYAIPAACHLTCVGSSRAELDEILQRMQDAGIRNIVALRGDPPLGET
RFVPPSDGCAHANELVRHINGFTRRKGGEPFGIAVAGYPEKHPEAPDLETDLDHLKRKVD
AGAQVIVTQLFFDNRHYFDFVRRARAKGIRVPIVPGLMPAQSADQIRRMTRYCKTDLPNE
MMRELEAAGDDEARACEVGVRWTIDQANELLREGAPGIHFYVLNQFESIRRICEKLKR
>A0A7X7FS99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MLFTQLHKQKPLVISFELFPPKTTEAEAKLFEQTIPEMLALEPGFMTCTYGAGGSTREET
MRIVTRIRQQFGIEIASHLTCIGASRESIAAYLARMRENGINNVLALRGDPPLNDPNYRP
ALEGFRLAINLVRYIKGVGGFDIFVAGYPEGHPECPDKHLDWQRCADKVEAGADGVITQL
FYSTNDFFEFDDYLRNKLGVTVPIVPGILPILSSSQIRRFCGLCGSKLPPEVSAQLDKLA
NDNEACRQYGIDLATQMCDELIRHGVPGIHFYTLNRVGSTRAVMRNLGLAGSPSGL
>A0A521N2G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKITDHIQQSKDTLVSFEVLPPLKGKTITSLYDHLDPLMDFKPSWINVTYHRSETMFKKK
ADGTFEKVDVRKRPGTVGICAAIMNHYRIDAVPHIICGGFTKRETEDALIDLDFLGIDNV
LVLRGDAAKNEAAFEPEKDGNHYAIDLLQQVNNMNNGIYLDEDIKNGGKTSFCMGVAGYP
EKHFEAPNLEIDLAKLKQKVDAGAEYIMTQMFFDNQKFYDFVKACRENGITVPIIPGLKP
ITNKKQLSVLPRIFHVDIPTDLSNAIMKCKTDQECEQVGTEWLVQQSKELKAFGVPVLHY
YTLGKPKVIWNVVKEIR
>A0A372ZRW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora xanthocidica|TrEMBL
MDHTTRRTPRGLRDILAAGERTYSFEFFPAKDEAGERALWAAIRRVEAVAPTFVSVTYGA
GGSSRDRTIGTTELIAAQTTLRPVAHLTAVGHSTAELQAVLRRYADVGIRDVLALRGDPP
GNPNGRWEPHPQGLRYAAELVRLVKECGAFTVGVAAFPERHPRSADWEDDIRHFVAKCRA
GADYAVTQMFFDVEHYLRLRDRLAAAGCATPVIPEIMPATDVRQISRFAELSGASFPAGL
ARQLEVARGDRATAHRIGVDHATRMAERLLHEGAPGLHYITLNRSTAALEIHRNLALTTP
TPRPLTPTAA
>F7VNA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)|TrEMBL
MDRMYNFGPKFIDITWGAGGRIAELTCEMVAQAQAYLGLETCMHLTCTDMGEEKVNNALQ
RAYKAGCTNILALRGDPPREKEKWEAAEGGFQYARDLVAHIRKLYGDHFDIGVAGYPEGC
DDNKDEESLLDHLKEKVDMGASFIVTQMFYDVDNFLRWVKRVRERGITVPILPGIMPIAT
YASFLRRANHMNCKIPEEWMAKLESVKNDDVAVREIGKTLVAEMCRKIVAAGIHHLHFYT
MNLAQATRMVLEELDWLPSPNRPLKRALPWKQSLGSGRRDEDVRPIFWRNRNKSYITRTQ
DWDEFPNGRWGDSRSPAFGELDAYGIGLTGSNELNRKKWGEPQTVKDIANLFVRYLNQEL
EYLPWSEAPISSEADLIKDDLISLNNRGLITINSQPAVNGVKSTHPVHGWGPANGYVYQK
AYLELLVSPELFPEIKRRIENHPDITYYAVTKSGNLHTNAPSEGPNAVTWGVFPGKEIVQ
PTIVESISFLAWKDEAFQLGIEWARCYDADTPSRLLIEEVMNKWYLVNIVNNDFHQPRTI
FDILGDLSVSDLEKVYTPAQTNGATNGV
>A0A3M3ZB62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. tagetis|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1N6UKJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas alcaligenes|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVGVPTAPHLSCVGDSKDELRSLLSQYKNSGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGDHFHIEVAAYPEVHPQARSYEDDLQNFVRKCRAGANSAITQYFFSADCYFY
FVERVRKLGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDLDSIQAFG
EQVVTEMCERLLQGGAPGLHFYTLNQADASLAIWNNLKLPR
>A0A660W2T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSELKSGSNLERLLAAGHFVVTSELGPPKSTDVSLVDKKADFLAGKVDAVNLTDNQTAIV
RISSIAAGKLLLDRGLEPVVQMTCRDRNRLAIQADILGAYVLGMKNILCLTGDHQCFGNH
PTARQVFDIDSTQLIRMVKDMRDEGKFACGDEIRQGKKGQLAPPRMFIGAAANPFADPVG
FRAARLAQKVSAGVDFIQTQCIYDMDRFVEWMKQVRDRGLHEKVKILAGLTPLKAYRMAM
YMNSNVAGIRIPEKILKRMEAAQDGPAEGVKICQEQIQQLREIQGVAGIHLMAIEWEHKV
PEILEGANLLPRPTLE
>A0A1G5YTV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium qingshengii|TrEMBL
MNQFRFSRRPDIGDKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHEVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEVEAA
GSAAA
>A0A2M8FHB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium CG_4_9_14_0_2_um_filter_37_13|TrEMBL
MKVIEHLLKAKEPLISFEIIPPKRGGDIKSLLHVVDDLSKYNPPFIDITSHGAEIVYEET
PQGIKKKIIRKRPGTLGICALIQNKYNIEAVPHILCKNFTREETEDFLIELNYLGIENVL
AIRGDDNGFVKPVPHGRSANEFAVDLVSQVNAMNNGKYLEENLLDAKATDFCVGVSGYPE
KHFESPNLKLDIKYAKQKIDAGAHYIVTQMFFDNNVYFDYVNACKEEGIDAPIIPGLKIL
SLKSHLTNIPRNFYINIPEALAEEVMSAKPEHVLEIGVNWAAKQAEELLNRDVPSLHFYI
LQNSKPINLLMKKLNLHFKKLVVKK
>A0A3C1Q3X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
AGIMPITTISSMKRMADLAAGSRFPAKLLKRLSVADGDAAAIRQAGIDHAIEQCQELIEQ
NVSGLHLYTLNKSSATREIANALTF
>A0A352XKV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHIRDILRHSKPSFSFEFFPARTEASAEDLYQTISELEPLAPSFVSITYGAGGGTRELTH
QLVARIKETTGIPPIPHLTCVGHTKAEVEQLLLRYAALGVCNILALRGDPPKNQNDYDWS
HGDFRYASDLVRFIREFNESGRHPLGGFGIGVAGFPEGHPTTPNRLAEMEHLKAKCAEGA
DYICTQLFFDNHDFFDFRDRCVLEGINIPIIAGIMPVTSLSSMKRMAELAAGSRYPAKLL
RVLSRAQDPQAVENVGIHYAAQQCNELLDGGVDGLHFYTLNKSSATRQIYQSLGMVTSA
>A0A2E3EAI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHINDIIGKEKPTISFEFFPPKTEKSSQSLFECIKELEDLDPSFVSITYGAGGSTRELTH
ELVVRIKDSTSLTPVPHLTCVNHTEEEIFSILEKYAEHGISNVLALRGDLPAGSTAHDRS
NDAFEYASDLVEYIQKFNGSGKCTDPRGFGIGVAGFPEGHPETPNRILEMDHLKRKVDSG
ADYICTQLFFDNHDFYDFKERCRLSGISVPIIAGIMPVTSAKGILRMAELAAGARIPGKL
LKAIDRCDGDTESIKRVGIQYATEQCSDLLNNGVDGIHFYTLNRSDATKGIFQSLGLQRK
>A0A3L7SEB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MPRPVSIKDAYQDGRLALSFELFPPKTAESEAAMWSTVDELASYGPALVTCTYGAGGSTR
GRTLEVIEGVRRRHDVPVASHLTCVGSSIDDLRGYLSEARQRGVAAIVALRGDPPQGATS
FQPVAGGLRYAAELVALIRAEFPQFAILVAGYPETHQEATSPEADLENLRRKCAAGGDVV
ITQLFYDNADFFRFRDRCQALGISAPIVPGVMPVTNYAQIRRIAALCKARLPESFTSAFE
AAGNDEAAQFEAGVTFAARQVEELIAGGVPGIHFYVLNRSPATVRVLGHVGLKPASRS
>C5EGI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium 1_7_47FAA|TrEMBL
MKTSEFFKQKTVLSLEVFPPKRTAPVDTIYKTLDELKGMTPDFISVTYGAGGSENSRATL
EIASSIKHRYGIESVAHIPCLHLTKEDAAEILLQLKAHQIENILALRGDRIPDREPAGDF
KYAADLVGFIRDHGDFNIIGACYPEGHQESGGLVRDIHNLKHKVDAGVSQLITQLFFDNG
YFYRFRERLDLAGIRVPVEAGIMPVVNKKQIERMVSLCGVRLPKKFTSMMERYGDNPVAM
RDAGIAYAVDQIVDLAAHGVDGIHLYTMNNPYIANKIHEAVFRLMAS
>A0A4Q5UGU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
YYSFVRDCREAGINVPIIPGLKPIYNRKQLNMLPKTFHIDLPNELSNEILKCKTDEEIER
VGQEWLLMQSKDLKKNGVPVLHYYTLGKPHVVANVVREL
>A0A432H3E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MVWNPEGSVVLEVLPPTLKSGLEGLHRRLSRVRRLIENGDFDAVNIPEIHDEENRNDRGH
RRHEYSARMQPRELGRRIQDELGIPAIVNHVVSFDPADQFLDWVNETVQGHDIHNLVLVG
APHDRRQWPGPAVGEANQLIRQQFGSSEVCIGNICIPQREDSPISEAVRMEQKVQDGADF
FSTQIIFDAADIISLLSDLQVQAPNACGVPLLVSLCPVKRIRQLGFLRYLGVRVPDHLDS
LLATVPEAYCLDLSLEILSNIQGTLIDHQQQHQSGPLLGWNIAPVGPIPIDAIETLMDRL
PGSIRS
>A0A2E1RTH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHIKDIINKGQPSFSFEFFPPKSDKSSDELLKTIKDLEPLDPSYVSITYGAGGTTRERTH
ELVEKILDLTNLVPIPHLTCVQHDEEEILRILNRYCDKGVSNILALRGDPPRGNNNYDRS
HDTFQYACDLVKFIRGSAKKTKSLGIGVAGFPEGHPETPNRLKEMDHLKAKIDSGADYIC
TQLFFDNHDFFDFRERCILAGIDVPIIAGIMPISSMQGLERMANLAGGSRFPAKLLKSLR
RCDSNPASIEKVGIQYATEQCSELLNNEVEGIHFYTLNKSEATKGIFESLGINKTSK
>A0A656IN89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enteritidis (strain 2009K0958)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2C6BM13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. polymorphum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPIDRELEIGD
FNYAKDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A355SAW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MQGTTNIAEVLGQEKPTVSFEFFPPKSAAASERLFSTIHELKQLNPSFVSVTYGAGGSTR
ERTHKLVLRIMEETTIPAIPHLTCVNHSTEEIEGILSGYADAGVPAVLALRGDPPGEDIE
YNRNQDAFPYASDLVSFIQGFNQEAKTQQKGFGIGVAGFPEGHPDTKNRLKEMDYLRQKV
DAGADYICTQLFFSNYSFLDFRDRCRLAGIDIPIIAGIMPITTRSGMERMADLAAGVHFP
AQLQRMLQGANDDPAAFETAGSDYATIQCRELLSEGVDGLHFYTLNKSSATRQVATELNL
GR
>A0A3C1H683|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MELIRDIQAGCLKAGRPAISFEFFPPKTEEGERNFFERVLPDLVALGPDFCSVTYGAGGT
TRDKTLGIVERIQRDHRLTAMTHLTCVGSTRDQLVGVLEDARRRGIRNVLALRGDPPGGQ
GEFVRTPGGFEYSHELVSLIHGMGGFCIGTAGFPEGHIACKEGREVDWGRLKYKIDRGAD
FVITQLFFDNDDYFRFRDHLARLGNTVPIIPGIIPILSATQIKKFTALCGARIPEKLVSQ
LDALGTDDEAAVELGIRYATEQCEGLLKAGVPGLHFYALNKARSTAAVVRNLGLARK
>A0A292YGT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lebetimonas natsushimae|TrEMBL
MKEKLLSDRLITLETTPPKLPTIDPMIEKIKKTEAYKYIDGFTTTDCPLSKLKYNSIIAA
YKIQQTFNKKVIATMSMRDRNIIALQSDLLGANDLNVTNILALTGDPAKMSDQPNAKAVV
EGSSLKLLEIIRAFNSGMDYAGKEFKIKPKQITPFAVSNSYAKNFSSIEKKIYKKVKNFA
LGIITQPVYDLEIADKLLEIRDKIRNSFSDERKNFDMILGFFPITKLKTAQFLHSHVPGI
YVPDSWIDKLIKAHKISENEEYKVGLELSRNLFNNLQKKHPKIHIMTANRFEIVKELF
>A0A3D8MVM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradymonadaceae bacterium TMQ3|TrEMBL
MSQIQMQSPFLKALAAGPIVFDGAIGTQLYERGIYINKSFDDANLSRPDLVAAVHAEYVS
AGAEVITTNTFSSNRIKLKRHGLEERAAEIALAGARIAREVAGDLALVAGSVGPTGRTPT
MLTERELDEMRQAFREQIAALAEGGVDVIVLETFRQLAEIRMALEAAREVCDLPVIAQMS
FDGERRTGDGADPERVAMLLADWGADVVGANCMEGPHVLYDVVVDMLSCGLPVIAQPNAG
YPRKVDERLVYMATPEYFGVYARRFFKAGVRLVGGCCGTGPDHIRQVAAAARMLGGGRAS
VEVSTARMPRKEVEPECVQSQKAPTRLAEKIEAAHRSRAAGEPVSRENFVVSVEVNPPSG
LRADRAIEAARMLVEGGVDVINIADGPRASVRMANWALGRMLQESLDIEVILHLCGRDRN
LLGLQSDVLAFEALDLRNLVVITGDPPKVGDYPHATAVFDLDSVGILRMIDNFNHGVDPA
GKPVGDATAFYCACGAEPAAADYERELRRLELKKAAGARFVMTQPVYDPAVLDRFLADIE
HLDLPVLVGLLPLASARNAEFLHNEVPGMAVPLEVRERMRAAGTGQAARAEGVRIAQETL
EAVGSRVAGAYIMPPFGRYEAALEILSCLPGYATT
>A0A6N7ZBQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis pithecellobii|TrEMBL
MVSPTDRDTSRVSGLLHDFSLEITGKDVGDLQKAAAGVPQGTRVNVTFLANEQTSVRVRA
AEVIKGLGFRPVPHISARRLTSRDELDRYLSALAEIGATEDVVVIAGDPAHPAGPFADSL
AVIASGALTEYGVRSVDIAGYPEGHPKIHEDVLWRAVEEKTDALRARGLDYSVATQFVFD
AATVVRWIEQLRGRGIDGPVRIGVPGPAGVQRLLRYAKRFGVSSSASVVQKYGFSLTGLL
GTAGPARFIADLQSAIDPALHGEILLHFYTFGGVRATAEWVRTALSGEE
>A0A8C2YLB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chinchilla lanigera|TrEMBL
MVNSGEARGDGGVSSGSEGSKDSSRCSTPSLDPERRERLREKMRRRMEAGDKWFSLEFFP
PRTAEGAANLLSMFDQMATGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETVL
HMTCCQHSPEEITGHLYKAKQLGIKNILALRGDPLGGQWESEEGGFDYATDLVKHIRSDF
GDYFDICVAGYPTGHPEADSFEEDLRHLKEKVSAGADFIITQLFFEADTFFHFVKACSEI
GITCPILPGIFPIQSYSSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAICNYGIELAVSLC
QELLASGLVPGLHFYTLNRKMATTTVLKRLGMWTEDPRRPLPWAISAHPKRREEDVRPIF
WASRPKSYIYRTQDWNEFPNGRWGHSSSPAFGELKNYYLFYLKSRCPRQELLKMWGEELS
SEESVFEVFAHYLSGEPNQHGYKVTCLPWNDEPLAAETSLMKEQLLRVNRLGILTINSQP
NVNGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGE
NITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSR
MMIQYIHDNYFLVNLVDNEFPQDNCLWQVVEDAFELLNRPAGLSREAEAP
>A0A345CYK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia tracheiphila|TrEMBL
MSFYHANQREALNQNLAELNGQINVSFEFFPPGTSEMEHTLWASIDRLSSLKPKFVSVTY
GANSGERNRTHSIIKGIKERTGLEAAPHLTCVDATRNELRAIAEDYWRNGIRHIVALRGD
LSASSDKPTMYGVDLVALLREVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIEAGANRA
ITQFFFDVEGYLRFRDRCVAAGIDVEIVPGILPVSNFRQLQRFAALTNVRVPGWMNSMFD
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPALCS
>A0A4V1TPE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MTTQTSSACPVSFEFFPPKTPEGAEKLRAVRQQLYVRRPEFCSVTYGAGGSTQEGTFAAV
REILAEGVDAASHFSCIGATKGSVREQLATLKGMGVKRLVALRGDLPSGYGAGGEFHYAS
DLVAFIRAETGDDFHIEVAAYPEVHPQARSPEADLQAFAAKVRAGAHSAITQYFFNADAY
FRFVDDARRLGLDVPVVPGIMPILGSTQLMRFSDACGAEIPRWIRLRLQGYGDDTASIRA
FGLDVVAGLCETLRAGGAPALHFYTMNQSAATLALCDRLGLQQG
>A0A3R9GPD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDAAPKDDFTYAT
DLIEYIKTEAPHFNIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQNVAGIHLYTMNNAATAYHIYKATHALFNHHPSVQSF
>A0A3E0WBC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Subtercola boreus|TrEMBL
MSSPSAPTVSFELYPPRSEKAEAGLYETLEHLATARPEFISVTYGANGSTRGRSLAVLCR
LRELGVEPMAHLTCVGTTYAQESLVIREFLDAGVTKFLALRGDPPEGSTENDTFLGDLGS
AGELVQLVHRVQAEKEQFTQADVPGFPRAKRLKSGAKVTIAVAAFPNGHPRSRSVQQDLD
TLLAKEAAGANLAITQLFFHADEYLRFVELARAAGVGMRILPGIMPVLSEARLTKIVELT
GERMPGELLGQLQAAGSTEAQQRVGIEHARALSEQLLEGGAPGLHLYTFNQHHAVLAVLR
SLGLAPGAPGAGIIPESPISVSKGIA
>I0Q0Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis SK610|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A498S4L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acanthocheilonema viteae|TrEMBL
MALTVFSKISGNINSKTSSSSVAAGCLDYCGIDTMLHITCCQYTKEQSIRHLEQIKALGL
KNILALRGDLPRQDENTALYKYRALDLIRWIKEEYNDYFTIACSGYPAGHPEAPSYRADL
LYLKAKVDAGADFIISQIIFDCKIFENFLRDCREIGITVPVIPGILPIQSYESIRRIAEL
SQLIIPDSILVSLKPIKNDDDAVRNFGIRHAVDLCQTLFTNGSTTSIHLFTLNQEVSSRE
ILQQLGLWPRSPVRTLPLRLFGENHPMRCKENVRLIFWSLRPKSHVFRTRWIVLVRRDDF
PNSRWGDSSSLVFSDLKDYYLFYLKGQSIQDEQLRMYGERLEILADIQKNPFVGWRKPSG
YCYQKAIIGQTNTESVMPTAVTLGVFPGSEIVQPMMVDPPSFRVRKDEAFDACLNCDLVM
QINQRCDCGVISLLFRFSHIDSANRLVDLELVMRSILNDITHFYCYYYSWDIMQH
>A0A317JHQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrio sp|TrEMBL
MHVIEHLEKASDPLFSFELVPPPRGASLNAIIEIVEALAPLQPPWIDVTSHSSTTYYRER
PDGALERKTFRKRPGTLGICGIIQNRFRIDTVAHVLCLGFTREETEDALIELNFMGIHNV
LALRGDQPNFQKEVRRDRTVNQYAAELVQQIGDLKTGKFLEDMEGSHPLSFCIGVAGYPE
KHFESPNLRLDVSYLKKKIDAGAQYIVSQMFFDNQKFFRFVELCREAGITVPIIPGLKVI
RSLSQLKTLPRTFHIDLPDDLVGEVIASPDHVEEIGAKWAHRQSLELLEYGCPGLHYYVL
NDAKVVVDLVKKLKK
>A0A542U8J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces puniciscabiei|TrEMBL
MNPALTVTPAVGAALLDDFSLEMTGKDVPRLEEAQDSIPQGTRINITFLAGEDLGMRLAA
ARAVKRLGFVPVPHISARRLPSRAALEEFLSGLAEDGTAENVLVVGGDPARPEGPYADAL
AVLRTGLLQRHGVRHVGICGYPEGHPAIADGTLWTALTDKTAALGAHRFAGDVITQFGFD
VDPVLTWLEAARARGVHLPVRIGVPGPAGVRRLLGHATRFGVATSASVARKYGFSLTNLM
GTTGPDRFLHALAHRYDPERHGVVKVHFYTFGGLRRTAEWIAGFRQAVPQVP
>A0A662B184|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MMVLFEEYVKENLVLLDGAMGSLIYEKGVFIDKCYDELNLSRPELIGSIHEEYVRAGSRV
IETNTYGANRFKLKSHNLLDQIEEINLKGVALARQSAGDEVYVAGSMGPSGQEIEPWGDT
TLEEVFEGYAEQARILNQAVVDLFILETFQDIREMEQAIKAIKSVSGLPVVAMMTVGEDG
LTRYGVDLEDVTNALTKSEASVIGLNCTVGPKPMLDFVEQMGRLTDKPLCLMPNAGRPQF
TDGRMIYMSTPEYFSVYTKRFIERGVRVLGGCCGTTPEHIGKMANALAMKQTRIQHSINI
GVKPVSEEPLPEPVPVAEKSKLSAKMLSGQQVVLVEMVPPRSTDITKPLEGARLLQEHRV
DAINIPDGPRATARMTGLALAVLLQNQVDIETVLHYTCRDRNLLGMQSDLLGATAMGIRN
ILAITGDPPMIGDYPQATAVFDIDSIGLVHLINNLNHGIDVGEKRIGDPTSFFAGVGVDP
NSVNPENELHRLQLKKEAGAEYIITQPVFDVDSLEKFLEKADLGSLSLIAGIWPLVSLRN
AEFMKNEVPGVYVPDEVISRIAKYETKDDQLKAGIEIAQGMIDRVAGFVQGIQVSAPFGR
YKLAVEVAGAMLKRNK
>A0A7X7LV22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera phenolivorans|TrEMBL
MSKTELSIEFFPPTTPEGAEKLRATREQLAELKPAFFSVTYGAGGSTRERTFATVKEIAA
SGCEAAPHLSCIGSTREGIRAILQEYADAGIRRIVALRGDLPSGVGDPGEFRYANELVEF
IRRETGDRFRIEVAAYPEWHPQARSPRDDLLAFKRKADAGADSAITQYFYNLDAYLHFVD
AARRLGVNIPIVPGIMPIGTFSKLARFSDACGAEIPRWMRKTFESYGDDSASVRAFGLDV
VTRLCEQLIAAGAPGLHFYSMNQAGLTTEICRRLGLDR
>A0A7V4IBM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MSLFTPVRRWQPPFRPFKRQRFFLRLLAGAERIIKGPLFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGSTPEHCYVDKSRKCVWYLIYRRAARMGRDEKLMEVLPPLDWDKTGCETW
ADVILQLRKTGTGNFARGMLSRNPEIRHETWESVFRPVRQPDWWNGDSVYHSPDYDQPAS
SLEKKLREGEFVFTTEVLPPLHSDITRLKKNIEAVKPYVTAINFTDNSSAIPRMSGQSCC
KVAAEMGADPVLQLTARDNNRYSLQAKALGANGEGIRNILCITGDSPVTGSKPTGSLEMF
DLDAVQMLWILRRLRDEGKYLDGRELKFRPSYFLGAAASPLASKPEFQAAREHKKVNAGA
QFLQTNLIFDIGQLEEWLEHLYKRNITDKVYIIVGIAPLKSLRMAHHFNNEVPGVAVPGH
IIKRIENAGDRAEEEGFQIALELTEKISKMKYVNGIHLTTMGCESTVERIVRDSGIKANV
EKYRL
>A0A7V6AM36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MAKIIDKLKTASRTLFSFELLPPLKGHSIDEIYRSIDPLMEFNPVNINMTYHQPEVVYVP
ASDGLLEKKVVRKRPGTLALVAAIKFRYNVTVVPHVICAGHTKEEIEDILIDLNFLEIKD
VLLLRGDAPKGQKVFIPEKGGHAHTVDLVKQVKNMNNGIYLDPSLKNPVKTDFCIGVAGY
PEKHIEAPNKETDLRYLKEKVEAGADYIVTQLFYDNKKFFSFVEECRAMGIHVPIVPGIK
PTTLLSDLRLLPQIFAVSMPQELVSELEKCKTNQEVREVGVEWAIHQCRELIRYGVPAIH
FYTYGMTENVARIARAVF
>A0A6I5A9R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter werkmanii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A151YXC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoactinomyces sp. AS95|TrEMBL
MGEQGLLQCLQHSLLVGDGAIATFLYQQGVSIGHCTEELVLSNPSLIGEVHEAYYRAGAR
VIETHTFGANRERLSRYGLESKVTRLNREAVHIAKESIGSDAYVLGVIGSICAGKVPVYD
EEEYRAMYEEQAVALLHGGVDGILLETFFDLKELQLAVEVIRPLTTLPVFAQLSMMEIGR
TRDAFTISEAFEKLASLGVNGVGINCRFGPVEVLRTLEKTIVPEQMILTAFPNAGRLGMS
NGELHYKSAPDYFEETAGLLIDQGVRLLGGCCGTTPEHIARIAKVLKDKCPVQRKNPPQD
GYKLSSHETIVLQRRTKPTVVQKVRNKQRTIICEFDPPKDLDIMRFLQGAKKLKQAGVDA
VTMADNSLATARMSNLALGAILKKYDIEPLVHVACRDRNLLGQQSHLMGLHALGIDQILV
ITGDPTRMGDLPGAHSIYDVTSVELIRMVKQLNEGISFSGRKLKQKAQFVVGAAFNPHVR
KLDAAVKRLEKKIEAGADFVMTQPVYDPDGVIRVHEATKSLGIPVFIGVMPLTGYRNALF
LHNEVPGIKIPEDVLKRMEKTTDRQSGKSEGVQVAKELLEVAMEKFDGIYLITPFSNWQM
TEELTHFIRWRDKEMHARLQSHTHA
>A0A8B8UA05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Camelus ferus|TrEMBL
MDRPKPRVPAVGPCCPSRGMRASEAGSARFSVPPCIRNSAMVNEPRGNGGPNPRSEGSSS
GSESSKESSRCSTPGLDPERHEKLKEKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRFD
RMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITGH
LHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYAADLVKHIRGEFGDYFDICVAGYPKGH
PDAESFEADLMHLKEKVAAGADFIITQLFFEADTFFRFFKACSEMGITCPILPGIFPIQG
YHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCRELLESGLVPGLHFY
TLNREVATMEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGKELTSEESVFEVFVRYLSG
EPNQDGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGWG
PSGGYVFQKAYLEFFTSRETTEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGKLYEEESPSRMIIQHIHDNYFLVNL
VDNEFPLDNCLWQVVEDTFELLNRAPQNEREMEAP
>A0A7Z6TJT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ZS0098|TrEMBL
MALGTASTRTDRARTVRDMLASGKTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSV
TYGAGGSTRAGTVKATERIAADTTLTPVAHLTAVEHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNAVF
PDALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A7C0VMZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MGELLVDILKSPERTRVSFELLPPLKGDTIESLYKNLDPLMEFDPPYINVTYHREEVVYR
NVSDHLMERKTIWKRPGTVAISAAIKYKYRVMVIPHMICGGFTREETENALIDLNFLGIH
NVLTLRGDPERSARAFIPEPGGHAHAVDLVRQIMNMNRGIYLDEELKNATPTRFSVGVAG
YPEKHPEAPNRRSDMQYLKEKIDAGADFIITQMFFDNRKYFRFVDECREAGIQVPIIPGL
KPVATKKHLNYLPKTFGVDLPGDLVKEVEKCRDNKQVKLVGVEWAVQQCRELKEHGVPVI
HFFTMGRSDNIRKIVQAVF
>A0A7V2S3M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MNEPKVTEHIAASGKTLFSFELLPPLKGQDFSAIQQAIDPLIEFDPAFINITYHQQEVVY
DTLENGLMKKRTVRKRPGTVGISAAIKYRYGIPVVPHIICGGFTREETENALIDLNFLGI
KNLLVVRGDPPLGMKNFVPEPEGNEHAIDLVKQIVDLNRGHYLEKDIKNKRTTDFCIGVA
GYPEKHNESPNLESDLHFLKKKIEAGAEYIVTQMFFDNQKYFDFVKTCRAKGIDVPIIPG
LKPITSKSQMISLPQTFHVDLPEALVKEMLKCKTNAEVREVGIEWAVQQAKELLDFGVPV
LHFYTMGKSDNIRQIAEKVF
>A0A2G1YXU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sneathiella sp|TrEMBL
MSIKPPVDHSAALPPLAGHTSHGRLERVLRAGEFAVTAELNPPDSADPNEVFERGAVFDG
WVDGINATDGSGANCHMSSVSICALLTRVGYSPIMQISCRDHNRIAIQGNVLGAAAMGVN
NILCLTGDGVQAGDQPGAKPVFDLDCMSLLRTVRQMRDDGRFLSGRKITLSPQVFLGAAI
NPFAPPYDFRPARLAKKIEAGAQFVQSQYCFDIPMLERYMEQVRDMGLDEKCFILIGVGP
LASARAANWIRTNVPGIHIPDSIIERLAGAEDQKQEGKNICIEMLQQVREMPGVSGAHVM
AYRQEELVADIVYESGVLKGRKPWKREAAPGFDAVSEAVETVKGQIDQTIKPQDAVAAVS
EEQ
>A0A103L902|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. FL-7-2-10-S1-D7|TrEMBL
MKSIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAATATRTICERLAM
>A0A3E0R5R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
REETVYKRLPNGLLQEKVVRKRPGTVGICASLMHRYQTEAVPHVLCGGFSKEETENVLID
LNFLGIENVVALRGDQAKGESYFTPKPDGNNYAIDLVKQINDLNQGKYLDEDLQNTMATD
FCIGVAGYPEKHFEAPSLNIDIEHLKAKVDAGADYIVTQLFFDNSKFFAFVDKCREAGIT
VPIVPGLKPLVTKRQLSILPQIFHVDIPDTLAIEVLKCKDNAEVRQVGIEWCIQQSKELK
DAGVPVLHYYSMGKSKNIYEIASAIF
>A0A3S2FTE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.10.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A523H750|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTQHIEKANGNTLFTLEILPPLKGQTITSIFNTIDPLMEFNPPFIDVTYHREEYVYKE
LENGLLQKQVVRKRPGTVGICAAIQNKYNVDAIPHILCGGFTKEDTENFLIDIGFLGIDN
VMALRGDAVKNETYFTPEKDGHNYANELVSQISDLNKGIYLDDEIQNQAKTDFCIGVAGY
PEKHMEAPSMDSDIYFLKKKIKKGATYIVTQMFFDNEKYFAFVNKCRAEGITVPIIPGLK
PLATKKQLNLIPHRFSAELPDDLIMEVVKCKNNEAVREVGVEWCVNQCKGLIVAGVPILH
FYSMGKSDNIKAIAAQVF
>S2ZL59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium breve HPH0326|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQAVGEFNHASDLV
SYIRSVKPDLKVFGACYPEGHYQADTIDQDIENLKIKVDAGATHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A497D5L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MELKVTEHIAKADKTLFSFELLPPLKGQNIESIQKAIDPLLDFDPAFINITYHQQEVVYE
ELSNGLIKKRAVRKRPGTVGISAAIKYRYNIPVVPHIICGGFTREETENALIDLHFLGIK
NLLVVRGDPPANTRIFKPEPEGNEHASDLIEQVMNLNRGIYLDEGLKNATETDFCMGVAG
YPEKHQESPNFESDLHFLKKKIEKGASYIVTQMFFDNQKYFDFVKLCRSKGIDVPIIPGL
KPVSTQSQLVSIPKTFGVDMPEELVKEVLKCKDNKAVREVGIEWAVQQSKELLAFGVPVL
HYYTMGKSDNIRKIAERVF
>G1X9G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491)|TrEMBL
MHIKDKIAACEKAGKPCFSFEYYVPKTAQGVQNLYDRMERMGSFGPQFIDITWNAGGRLS
NLTTEMVNVAQTVYGLETCMHLTCTGMEKEKVDNALQEAYNGGCTNILALRGDPPRENEK
WSAVPGGFRYAKDLVKHIREKYGDYFDIGVAGYPEGCDDEVDPDILLDHLKEKIDAGGTF
IITQMFYDVDIFLDWVNKVRAKGITVPIIPGIMPIHTYAAFIRRATWTKIHVPEKWLEVL
EPVKNDDVAVRDIGRDLVVELCKKILAAGINQLHFYTMNLATATRMVLEGLELMPSLEAR
ELPALPFKSSLGLGRREENVRPIFWKNRHKSYVARTQEWDEFPNGRWGDSRSPAFGELDT
YGIALKGTTEQNIKLWGRPETVAEIADLFVRYIDGKLETIPWSDSPIDASAEPIKAQLSE
LNKRGFLTTNSQCALNAVKSSHPIHGWGPKNGYVYQKMYVELLVSPDVLSELITRIERSS
DLTYYAVNKAGVLHHNAPAGGSPNAVTWGVFPGKEIVQPTIVELISFLAWKDELYRLGED
WAACYPQSSASRHIISSVMENWFLVNIVNNNFLDNDSIFELFKDLKIDNLNEKIPVDEYL
QNLKITDGINGTAHEATNGAPAA
>A0A563EFP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentzea tibetensis|TrEMBL
MTSVVERLRGDGLKFSVEFLPPRDAADELVLWKAIRELESFDPAFVSITYGAGGSRRDRT
IRATGRVAQETTLLPVAHLTAVDHSVAELRNVIGWYAAVGVRNVLALRGDPPGDPMGEWV
AHPEGLQYAEELVRLVRELGDFSVGVAAFPYGHPRSSDLDQDVEYLVRKLNAGADYAIAQ
LFHEPEPFLRMRDRVAAAGCPAVILPGMMPMTTVRSLNKIVELSGAPLPDDVRKRLEPYL
DDPAGFRATGIDLATEMCARLLDEGVSTLHFYTMNRSKATKEVLGRLGLVPARA
>A0A661XRY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHLKNADKTLFSLEILPPKKGDNINDLFDHLDPLMEFNPPFVDVTYHREEYVYKKM
PNGLLQRKTTKKRPGTVGICAAISVKYNVDTVPHIICGG
>A0A355UA13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKLTEYIKPGKTLFSFEVLPPLKGKSIDSLYHGIDPLMEFNPAFIDVTYHREEFIERPRK
DGGYDKISTKKRPGTVAICAAIMNKYKVEAVPHLICGGFSKDETENALIDLAFLGIENVL
ALRGDNLKNERNFVPEKNGNSNALDLIRQIADMNNGVYQDQELQNVTETNFCIGAAGYPE
KHSDAANMVSDLKFLKRKVDAGAAFITTQMFFDNQKYIDYVAMCRAAGIMVPIIPGIKPI
TTKGQLRALPKIFNMDIPEPLASELEKAKDDTAARQIGIEWCIQQCKELKSLEVPALHFY
TMSFSSAT
>A0A4Q6ISX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. F001|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFYAPKTAKGERSLWNALRRVEAVAPDFVSV
TYGAGGSTRASTVKETEQIVADTTLTPVAHLTAVDHSITELRNVIGQFADAGIRNMLALR
GDPPGDPMGEWVPHPTGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDTDVTHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVMPVTSVRMLERLPQLSNAHL
PSTLKERILTAKDNPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A2E4Z3P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSDTNPLGAHLPLDPKPGHSSLGRLERVLRRGEFAVTAELNPPDSADADEVXDRAAVFEG
WVDGINAVXASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMGVC
NIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESRFLSGRKLTKPPQVFLGAAI
NPFVPPQEFRPMRLAKKIAAGAQFVQSQYCFDVDMFRTYMQRVRDLGLDEQCFIMCGVGP
LASARTAKWMRSNVPGVHIPDHIIKRLEGAEDQKAEGKRLCIDIINEVKEIAGVSGVHVM
AYRQEEYVAEIVHDSGVLKGRKPWRKEPNFANEAAEARLEDADAAASATPHALAGAAAES
EA
>A0A365MQS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella intermedia|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKTKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAMYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A433CKS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIGELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDLDIQRFVEKVNAGANAGITQFFFNPDAYFYFV
EQIEKAGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A223V6R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter cobaltidurans|TrEMBL
MKVTEHIKQAKGKTLFSFELIPPIKGKSIQELYDNIDSLMEFKPPFIDVTTSREEYVYID
KGGLLEKKVTRMRPGTVGICSSIQHKYHVDTVPHLLCGGFTKEETEYVLVDCHYLGIDNV
MALRGDSIKEERYFTPTEGGHCYAKELVEQIRNLSHGQYLHETITSDDYPDFCIGVAGYP
EKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVEAAKNLGINVPIIPGIKP
VAVKRHLQLLPQVFRIDIPQDLIDAVENCKNNKEVRQIGVEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAKEVF
>A0A1J0AGC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gloeomargarita lithophora Alchichica-D10|TrEMBL
MNNPCPPLSRLQQGIHRGEFLITAEVMPPKGGNPAQMLQMAQLLHPWVHGINVTDGSRAV
LRMSSLAAASLLQQHHLEPIYQLACRDRNRIALQADLLGAHGLGIRNVLALTGDPVKAGD
QPKAKAVFEYESVRLLQVIQKLNQGGDSENQPLPDGALTLFPGAAVDPQSGSWSGLQSRF
ERKLQAGAQFFQSQMIVDFDRLEKFMTQIAQGCGRPILAGIFLLKSAKNAHYINKYVPGV
QIPEALIQRLEQAEQPLETGITIASEQVQWAQHLCQGVHLMAVKREDLIPEILTRAGLSS
TIPAPYTPPAPPDPRVHGAKPAGEIPEK
>A0A485NQQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lynx pardinus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEASSRTFSVPPSISRNPAMVNEPRGDGGPTSRSEGSS
SGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DGTGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCCQSREQITG
YLHKAKRLGLKNILALRGDRVGEQWEEEEGGFSYAADLVRHIRSEFGDYFDVCVAGLPLP
SAACETVQAGGTAADQGRDRANQRQRRCHPQLWHRAGCEPVPGASDQWLGARPSLLHPQP
RDGHHRGAEAPGHVD
>D4KWG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia intestinalis XB6B4|TrEMBL
MRLTELLNTENVTISCELFPPKQGAQLDNYKKIVGDMAALKPAYMSVTYGATGGTSDYTV
ELANEVRNVNHIPALAHLTCASSTKEKVASVIQELKEKQIENVLALRGDIPQNADFPLPN
QYKHASELIYDIKSQGDFCIGGACYPE
>A0A7W5ICZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. WP4_3_2|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLQHKPRFVSVTFGAGGSTQQGTLDTVAEIAK
EGVDAAPHLSCIGATRDGLRDILNQYRSHGIRHIVALRGDLPSGMGEMGELRYASDLVAF
IREETGDAFHIEVAAYPEYHPQARSPRHDLEAFAQKVKAGADSAITQYFFNADAYFRFID
DAKKLGVDIPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTDLCRRLVDAGAPGLHFYTLNAAGATKSICERLAL
>A5N923|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)|TrEMBL
MNIKEKPLIFDGAMGTYYPRISKDPLPKCELANIYDRNTILKIHREYIEAGCMAIKTNTF
GANKVSLESDFNKVKEVIINGYEIAKEAAKDTEVLVFADIGPIPFLESMDLYEGYKEIVD
LFLELGAKYFIFETFSSDEYLREISEYIKGKDPEAYILMEFAVSPEGYTRVGKSGKKLIE
NILKIPTIDACGFNCFSGPYHLLQYIKTFNIGNETISVMPNSGYPTVIDNRTFFDNTKEY
FAQRMLEIAKQGVSILGGCCGTTPEFIRETVIKLKKLSKSEIVLKKQAEKIHTEKPVVKN
VLLEKINKGKKIIAVELDPPIDTEVDFFLNSARTLKEQEIDAITIADCPIARARVDSSLL
ACKLKRELDITTIPHMTCRDRNINATKALLLGLNIEGVNNVLVVTGDPIPSAERDEVKAM
FSFNSAILANYITNLNDTIFSSPFNICGALNVNSRNFNTELKRAKTKIENGIAVFLTQPI
LTEEALENLKLARRELTARILGGIIPVVSYRNACFMNNEISGIRVSEEIIKQYKDVSKEE
AVKLAVKISTDIAEQIYPYVDGYYLITPFKRIDIISEIINNIKAKNTITI
>A0A6G1I4S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichodelitschia bisporula|TrEMBL
MEKITDKLAALPQDGTYFSLEFFPPKTAMGFANLQARLERMSSALRPLFVNVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRALIDEVLEQARALGIRNILALRGDPPRSDD
YWEKDSPLSVDSNAEFTWAADLVAYIRKVYGDYFCIGVAAYPEGHSDQANPEAQSPTFDL
PYLIEKTKAGADFIMTQLFFDVKAYEAFEDILRNHPSEVFKTIPIIPGLMPIQSYQILRR
TTKLSHATLPPDVLTRLDAVKGDDGAVKSVGVDILTDIVGTLQKRPSKGPQGFHFYTLNL
EKVVSQIVERCMLIGNIGELADEVAIEIVDTANPLRNTSNSEHSRRLSSVHNSNPHNRVV
VERPTAFSHRNYEAIESEAGVLAGAINSRATTLAISEGEGALGREATWDDFPNGRWGDAR
SPAFGEIDGYGVSLHVSIPQAIKLWSYPTTKNDISTIFRKYIAGEIEAIPWSEEGLNTET
ETIRDHLLKLNAKGWWSIASQPAVNGLKSSNPVFGWGPRNGFVFQKPFVELFLPSQDWKE
LKAKLDDLPEVTYFAGNDAGAFDASDPAAVNPVTWGAFPGKEIITPTIIEAVSFRAWLEE
AFSIWKEWMQIYPIRSPTAQLLGNITGDYWLVNIIHHAFVENDALWELLAE
>A0A562N6V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium tianshanense|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRAYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDQVVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>V7ZGU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. carotae str. M081|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDT
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A2G2QQ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccus sp|TrEMBL
MNDRHLSFEFFPPKTPEGREKLRLVHRQLARFNPEFFSVTYGAGGSTRDHTRDIVLEINQ
AGSNATPHLSFGGDSKQSVLSLLETYREAGIRRIVALRGDLPSGMGGSTQLIYANELVHF
IRKHFGDTFELLVAAYPEIHPEAESYQKDIYWLGQKFSAGASRGITQYFYNIDAYFYFRD
QCLAAGIQNPIIPGIMPITNYQNLIRFSDNCGADVPRWIRQQLKSYGTDTTSIRAFGLEI
VTRLCEKLLAGGAPGLHFYTMNQADTCTTLCRNLGFPITDA
>A0A0M4KRW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus gilardii CR3|TrEMBL
MQDRYYSFEFFPPKTPEGREKLRNTRAQLAPLGPKYISVTFGAGGTTQQGTLDAVLEIQR
DGIDAAPHLSCVGSTREGIREILRTYRDNGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFQIEVAAYPEYHPQARSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRALGVDVPIVPGIMPITNYAQLMRFSEMCGAEVPRWVAKRLESFGDDREAIRAFGLDV
VTALCERLLAGGVPGLHFYTLNAAGATKAIWQRLKL
>A0A356CKN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MDVKLHISFEFFSVKTQHGLEKVHAMCTELARYEPEFYSVTYGAGGSTRSSTHDLAISLQ
RAGFETAPHLSFGSDDQADIIALLSTYKAEGISNLVALRGDLPSGLGGTKSLVHANELVA
LTRQSFGTHFDINVAAYPEIHPESESYHSDLYWLGEKLRAGANRAITQYFFNADAYFRFI
DEAQKVGIDAPVIPGIMPITNFLNLVRFSDNCGAEIPRWLRWQLKQRSADSEDLIRFGID
VVTQLCSRLIEGGAPGLHFYTMNNLAVTNELCQNLSLPRQL
>A0A5N8WXJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces acidicola|TrEMBL
MALGTASTRTDRAPTVRDMLADGRTTYSFEFWAPKTAKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVKATEQIASDTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPQGLTYAAELVGLIKESGDFCVGVAAFPEMHPRSADWDTDVSHFVD
KCRAGADYAITQMFFHPESYLRLRDRVAAAGCTTPVIPEVMPVTSVKMLERLPQLSNASF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A060SLQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pycnoporus cinnabarinus|TrEMBL
MKISKKIEQAAKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
ELTAELVKTCQKLIGIETCMHLTCTGMPKEKVDIALREAKQAGCRNVLALRGDPPVGKEW
EPVENGFRYGVDLVRYIRAQYGDYFDISVAGYPQTQRLPPDEREREMQYLKDKVDAGANF
IFTQMFYDVDMFIEWVQAARAAGITVPIVPGIMPIQTWNGFQKATMLAKITVPQAFLDQL
EPHKNNDEKVREIGTKLVADLCRRILAADIGIKGLHFYTMNLEKGCRLLLEELNLVPRIE
VIKPLPWRQSLTPNRRTENIRPIFWANRTRSYLSRTENWDEYPNGRFGDSRSPAYGELDG
YGVWIKQSKEDALRLWDTPTTVEDIRQLFAKFCKGELTALPWSDTAPSSETSVIAPQLAK
LNELGFLTINSQPAVDGARSDDRIHGWGPANGYVYQKAYLEFFVSPELLDLLIPHIERDV
NITYYVINNRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGRQW
AKVYEPESPTRKLIDGLMDTYYLVNVVHNDYKKPDAIFEPFYKAGAEYAAKYGSALQHPS
ANGTNDANGHAN
>A0A2D5R4K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MTPKVSFEFXPANTXSMEKTIRXSIEKLESXNPEFISVTYGADGSTRERTXDAIASIQAR
GTVDAMPHLTCVGALKEDIASIADEYYELGIRKIMALRGDPQGGAGAAYVPTEGGFPYAE
QLVEGLAAQHDFDIYVAAYPETHPDAPSPHFDLQNLKRKFDAGASKAITQYFFNTESYLR
FRDTAVRMGIDNPIIPGILPVTNFATLQRFSKASSIALPKWLETAFAGLDAEPETRQLIA
ANIAIEQVIALQAEGVNDFHFYTLNRAELCYAVCHALGVRRALTNENXTVEAAA
>A0A7V7HWG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AR2-1|TrEMBL
MKLLDLLSKGIVISDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVIDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEADTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A5N0V7H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis acidicola|TrEMBL
MGTMLHAAGNSLDRALPELNLSNSELVSTVHESYVAAGADLLLTNTFGANRLRLAELGGS
ATVRDVNMAGVRLARQARRGARRTVFVGGSVSPAAKAGQGAAYSPDERIDVIREQVTALI
DGGVDLLVLETFGGLGELLEAVAIAVETDVPVIAQATFTAEGRTLDGETPEEVAKALART
EVAAIGANCTVGPQHMLGIVKRLRGTLPVSAQPNAGIPRRIGRRFEYGVDGEYFARYARA
HAESGASIVGGCCGTTPGHIREVVARLADLRPPEQRRKVSKHKRSSEPARGKLAQRLRDK
EFVVAAQYSRPGDHQGVDLVFGKDIATMTAWDKTITTLQDELHGAHAFGLRTVVCETGSP
PPLGDYPDADGILEVDSIGLIELLAAFNAGRDRTGHTLVTRTAFHIGARFNPGAADLDAE
LVRTKAKIAAGAQFLVTTPVYDLESFAWMLTELSEEDIPILMSVHPLSGYAEAEYLAHEV
PDVRVPPDTLEALQAGERTGYEVAGELLAAARKLADGVVLHIRDSSEITKLLG
>A0A3M1QFZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLTCFLPDSRSIEDNPMAKIPFLERIQDEKPLLSDGAMGTMLHEHGIKIDACFDELNLTQ
PQIVAEVHREFIDAGAEMIETNTFGANRYKLAKYGLAGRVVEINRAAVNLARRVIDATFR
DDIYIAGSVGPLGVRLKPYGRVKPEEARAAFSEQIGALTQAGVDVVLLETFTDRHEILEA
LAAVRDVAPGTPVICHTTYSRDDRTLMGDLPAKVARELADAGADVIGVNCGGGPAQISRV
LQSMRQAAPNIIISAMPNAGYPESIDGRIMYPATAEYFGDYALTFKAIGASIIGGCCGTT
PRHIAAMREALDDPSRPLPQIHIPHYHHDDAEIVPEQPTDLSRKLAAGEFVVSVEVAPPR
SFAPQKMIAAAQLLQEAGADVINVADSPTARMRMSPWAVCHFLHDHVGIETVLHFPTRGR
NLLRVQGDLLAAHALGLRNLFVVMGDPTHIGDYPEAMDNYDVSPSGLIGIIKHQMNTGSD
QAGHSIGQPTSFTVGCALNMGAKNIDREITVLRRKIDAGADFALSQAIYDPATIDHFYAY
YEQVVGEPFTLPVLLGVIPLYSTRHARFLHNEVPGIHISDEIFKRIETAGDDAPQEGVRI
AQELLFAVQDKVQGAYIIPPFGHYELAADIIDAIKINARQPM
>A0A6L8RI24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens|TrEMBL
MRVDEVFKQAASQGTAPISFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRSRADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLSLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A7C1IW04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRRHALELVEDPQRISASSAFHLNLSSPKIISGSRLERVLKSGRFAVTAELNPPDSADPQ
AVYERALVLSTVCDAINATDASGANCHMSSVGICALLTRAGYEPVYQMSCRDRNRIAMQG
DLLGAAAMGVKNVLCLTGDGVQAGDQPEAKPVFDLDSMTLLRTVRVMRDHGQFLSGRKLD
VPPKVFVGAAENPFVPPYDFRPLRLQKKWEAGAEFIQTQYCFDVPRLAEFMKRVRDLGLH
EKLYILVGVGPLRSAKIADWMRNHVPGVHIPDEVINRLKGAQKQVAEGKKLCIEIIQQVR
EIVGVSGVHVMAYRQEELVAEIIEEAGLLPRRPIATAEVVGVPV
>A0A367ZQK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Ozemobacter sibiricus|TrEMBL
MEDFRSFIENNLVAFDGAMGTMLYSRGVFINQVFEELNLSNPSLVQQIHQEYLAAGAMVL
ETNTFGANRFKLTPHGLADKIEAINFQGAKNARHVAGDQAWVFGSIGPLGIRIEPWGKTS
VEEAEAAFAEQAAGLLAGGVDGFILETFYDLNEIRQAIRAVRKLTDKPVIASMTINEEGC
ALYGTTPEDFTPKLDQWGADLIGLNCSVGPKAMLDAVERMRKLTAKHLVVQPNAGMPRSI
DGRMIYLCNPEYFGEYAKRFIQAGVRAVGGCCGTTPEHIKWVRKEIKALESPGRRVFVVQ
PIKADRVDASAPQVAVVPLAEKSALARRVAEKKFVVCAELTPPKGCDPTNVIEAARQLKE
HGIHAINIPDGPRASARLSPLAMASLIEREVGIETVLHYCCRDRNILGIQSDLLGAYAIG
LRNILCITGDPPKLGNYPEATGVFDIDSIGLTNVVHRLNHGKDLGGNPIGKPTGFFFGVG
VNPGAIDLATEIRRFEWKVDAGAEFAITQPVFDITLLERFLEKISHVRIPIIAGIWPLAS
LKNAEFMNNEVPGASVPEPIMARLRAAPTPEAQREEGIAIAREALTKVRPLVEGVQISVP
FGRAPVVLKILEGISW
>A0A7K8AK43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cnemophilus loriae|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKENSRCSTPVLDTDRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFVITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7C5H6A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPSKFKEALNSGKFVITSEIGPPKGTNLEKMYHHIDLLKDRVDAINVTDHQSSVMRFPSI
GGCLAIKERGGEPILQMTCRDRNRLALQAELLFAYTRGIRNVLCLTGDAVPVGDHKEAKG
VFDLDSVQLLRAIRTLESGKDLGGNDLDGAVEFCAGAIVTPEANPIEPQLIKFEKKVEAG
AEFFQTQAIYDLEKFAKFMQFARQFPVKVLAGIVLLSSARMAQYMTENVPGIFVPQHLID
ELASAPKGTALQKGIEIAGRMIATIKKEGLCDGVHIMAIGREEVVPDILQAAGI
>A0A218ZR72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon B_DKE|TrEMBL
MTVKNVSNIGYIKSFELVSRRSYGYTEAQDAVDLLDGISNVITAPENPMGMPGIDPLMAL
YTATRGHDIIPIPHITPRDKNKLHIQSQVLTGLKFGINHFFAIGGDPIHKTMESREVREL
DVIGLIRAIKESRNYSKDFSSGTDISVGSSFNPFREAEEDIVKAKIGGGSGFFITQAFYD
SALLKREWVRKRDFKLIAGFMPIQKESQIEFMKKLGAKIPEETEKRILGAQDKVQESSRI
IKEMADDLDGYIDGIHIMPLGKNKIAKDILESF
>A0A7C5D4G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTLREKLSSGKFVVTAEVGPAKGVDTHEFLENVELLKNRVDAINCTDQQSAVMRLGSLAG
CYLIKQKGGEPIFQMTCRDRNRIALQSDLLNAYVLGIENVLCLTGDFVTLGDHPDAKPVF
DLDSVSLLYAARQLEQGKDLAGKELTGSPKFFLGACVTPGAEPLEPQLLKMERKVKAGAQ
FFQTQAVYEPKKFETFMKEAKKFGVPVLVGIVLLRSAAMARFMNKNVAGIHVPDELIAEM
DKAENKLQKGIEIAARLIKEMKDMCQGVHIMAIGLESKVPAILDAAGL
>A0A535Y7D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRSARPRSSSAPSPRPGLAERLASEVLVCDGAMGTMLHAGGVSLDRSLPELNVSHPPRVR
SIHRAYIAAGADVIETNTFGASRLRLARFGLSARVVELNRAGVRVAREAQEQAGVPSLLV
AGSISPATPAGLGQRLAVRELRDVLREQIEALCEGGVDLLLFETFGSLAELVEAIGVARS
LTVAVPVVAQMTFVEDGRTLGGDSPEQLATTLADLGVAALGANCTLGPQGLLEVLGELAR
WTSLPLAAQPNAGPPTLSDGRFQYTSSDPAYFARHARRFVELGATLVGGCCGTTPTHIQA
VAAAVAEMRPAAPRRLSTASSVIVSASRPRHAPEAETGNPLLERAASGELVVTCELPAPV
GAEAEQAVADAAELKDSGCHAVIVGPVGSTRAHVSPASLALLVQQRVAGIEVILTATTWE
KSLMVLQADLLGTYAFGIRHVLCRTGTPPPHGDYPNAAGVWEVDSLGLIEVLHGLNEGRD
YNGIPVGRPTRFVIGARVNPSANDFTHEVEGARRKLANGADFLVTPPAYDLEALERLLDA
IDPPAQVPLLLGVMPLRDVRHAEYLQHEVPEMNVPDHVLERLWQAGEAAPVVGDDIACEL
VRAARDRRRVQGLVLSSAIGSVAEMTRLLPRLTD
>A0A7C4NE83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSSNRALEFRQQLSRRAMVADGAMGTVLYSRGVFINRSYDELNLSQPEVILDIHRSYVEA
GAELIETNTFGANRFRLIEHELENKIAAINQAGARLARKAADESRRRIYVAGSIGPLGVR
LAPLGRVSPIEAFEAFKEQIAALVAEGVDALIFETFSDLGEITQAIKAAKEVAPGLPVIA
QMTFTEDGCTPLGDSADQVAQTLIDLGANVIGANCSVGPARLLPVIQTLAHRARMSERAP
LVSIQPNAGWPQRMGPRLVYPATPEYFGDYVRRFLDAGATLVGGCCGTTPQHIRAMRAVL
DEAELRATTRIAISVPRGGALAEAVVSEPVAPTQLAEKFAEKKFVIAVEVDPPRGHNANR
IIEAARELKHAGFDVVHIADTPMARMRMSAWALAHLIQRDTDMETVLHFPTRGRNLLRVQ
GDLLAAHALGVRNLLVLMGDPPSVGDYPEAGDQHDIVPSGLVKLIKGNLNTGKDSAGMTI
GAATTFHVGVAVNFNPPDLEREIKTFRKKILAGADFAVSQPIFDIAPVRLFFRRYQDQFG
AVPIPIMGGVLPPASLRNAEFLHNELPSIFLPDWALDRMRKAADGRKEGVRIAQEALAQL
RELVQGAYVMPMFGRYDSAAEVIEVVR
>A0A535QDQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAEFSDDHKARSNPFLQRLRRGALLGDGAMGTQLHARGVGFERSFDELNLTQPQLIEEIH
RAYISAGAELIETNTFGANRIKLARHGLEAQVRDINFKAVKLAREAREISGEPIFVAGAV
GPIGQQLEPIGRITIAKATAAFEEQIAALLEGGADLLVLETFTNLPELLAAVLAARRTSD
LPIVAQMTFAEDGLTLSAEEPTQVVQALEQAGVDVIGVNCGVGPQVALQVLESMRPHTAL
PLSGQPNAGLPARVEGRFFYFATPEYFANFARQAAELGVAYIGGCCGTTPAHIAAMRAAL
RPDTAAPQTRQPPSHTAVPIDLNPSEPLPRTPFAQRLADRSFVVSVEIDPPRGLNPAKCI
AGAQLVKAAGADAVNIGDSPMARVRMSALSLAVMIHRDVGIDTLIHFTSRDKNLMALQAE
LIGAHALGIRNVIALTGDPPRIGDYPSATGVWDVDSIGLIKILRRLNEGYDWLGTSIGRP
ATFTIACAVNPSAEDLQREIDRFRQKIDAGADVAMSQPLYDRPTLERFLERTGPLPIPFL
LGVLPLQSSRHAEFMHNEVPGITVPQPLRDRMRQAGENGIAEGLQQSRELLEDTKNLVQG
VYLMPSFGRYEVVAELIRWLRGQAIAAPTPR
>A0A536CDZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARITDLLAAGRTFSFEFFPPKDEEEQRLLTRTIADLQPLRPSFVSVTYRGGRISRERTT
RVVIDLLRTTDLTPMPHLTCVAHPRFELGEIIGGFRAAGLENLLALGGDPLPAEESYKEL
EYASELVELGRRLGFESIGVAAHPAGHPRSPDLVSDREHLAFKLRLADFAITQFFFKVEE
YERLRDELAARGITKPILAGIMPITSLVSVQRMAELSGYAVPADIVRRIEAGGDDREEIR
RRGIEVATELCRDLLDAGVPGLHFYTLNFSKATREIYTKLGLVTHR
>A0A2W1AF74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNRLALQSQLLGAQALGLENVVVVGGDPFIEGERGAAQAVDDFTPTEFIASISAMNEGID
YKGIKLPVPTDFCIGATVDLGRDLVVEAPLAHRKVEAGAHFLMTQTLFDPAQATQFLEAY
ARLSGAELAVPVFWGLPVLDKEGLTFGDVPEDMANDLKKERAGSEIALDLLKAFLDRGMN
RFYVVPPILKGGRRGYEQARQVVEAARRL
>A0A3A0AER0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
VRDLGLHERVYLLVGVGPLRSEKAAEYMRTKVPGVWIPDEIVNRLAKTPPKQQAEEGKRI
CIEIIEQVRQIEGVHGVHLMAYRQEETVAEIVHRAGLLPRQRGERSRGRPEPIREMEGV
>A0A3L7YJX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIHDILHTTHPVFSFEFFPPKTEEQQRQLLETIRRLGPLSPAYVSVTYGAGGSTRALTI
DTVNRIKEEFGIEAMAHLTCVGASRDDIRETLDTLASHGVENVMALRGDPPKGTKDFEPA
PDGFAHASDLIQFINENYDFSIGGACYPEGHFEGNTGRRQDPDMDLEHLFKKVKAGAKFL
VTQLFYDNEAYFQFVERARMFGIEVPIIPGLMPVVNAESIPRIAKMSGASFPESLMREVQ
ARASDPDAVVELAVAFTALQADELLRHGAPGIHFYTLNRSPATSAIVSALRLIRPWEVHN
YA
>A0A3C1V9J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MKFIRDIFAEKKAAGKPVVSFEFFPPKTDEGDRNLLEKQIPALLAAHPDFCSVTYGAGGS
TREKTLRIVDTIQRQHGLTALAHLTCVNHTRAEVGVLLEKIRALNCKNILALRGDPPGGG
EFQPTPGGFEFSSQLVQFIREQGDFSIGVAAFPEGHIANKNGKQADWQHLKEKVDAGADF
VVTQLFFDNADFFEFRDHAVNQLGVRVPIVPGIVSILSATQIIRFTQLCGSKIPPALRAK
LDQLGTDDETAMKFGIEYATQQCAELLRGGVPGLHFYTLNKAHSTVQVLKNLGLA
>A0A521S378|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAFLRRGGSAARLDPGPRAALAGLLESPTYELIPLKNALDQAAALPPGATVSVTASPAKG
IEATIDLAETLEAAGFRAVPHLSARMIRDHGHLKELLARLRGAGIDRTFVVGGDEEQPGD
YVDGFALLLAMADLGNGPREIGIPCYPQGHASIPDAALLRALRDKAPFASYMTTQLCFDP
PAIARFVAARRAEGLTLPLKIGIPGVAEVPKLMTISARIGVRDTGRFLMKNSRFVGQLLT
SGGIYRPTGLLEKLAPLIAEPRSGIVDLHVYTFNQVPSTEGWRRDYLAALTGTAGAAASA
>A0A4U7BDU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elsinoe australis|TrEMBL
MERISDKIAALPQDGTYFSLEFFPPKTQQGFDNLQSRLSRMSQALRPLFVNVTWGAGGST
STKSLALAELTQRQLGLTTCLHLTCTNMSRRLIDETLEQAKNLGVRNILALRGDPPRSEE
YKAENGDAPEIEDDDSNKEFTWAVDLVRYIKKKYGDLFCIGVAGYPEGHSDQSHPEHQSM
DFDIPYLVEKVQAGAEFIMTQLFYDQKAFDAWEELLRSHSSGAFKDIHIIPGLMPVQSFQ
ILRRTTKLSHAKLPEPVLKRFEDVKGDDEAVKRVGVDVISEMVETMKDSARNRPKGFHFY
TLNLEKAVAQILQRCDLIPPSTPSIITTLDSAISEEDSDGYLHVKKDDAQGRRRRASREA
NNRVIVDRSRRTSTHSSMYEQSEDEISRPSSLGPSRATALAISEGEGSLGREATWDDYPN
GRFGDARSPAYGEIDGYGTSLHVSIPQALRLWGRPASKSDITTIFAKHVRGELEAIPWSE
DSLNAETETIREELATLIQKGWWTIASQPAVNCVRSTDKIFGWGPNNGFVYQKAFVEFFL
PSSDWKRLKEALDQDEQFTYFAANDAGELEASNEDSVNPVTWGAFTGKEIVAPTIIEGMS
FKAWAEEAFAIWREWGLVYKPGSESSRLLKGIREDYWLVNVINHAYVEPKALWETLAKI
>A0A661WAI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAKSSFEEKLDANEFVVTTEVGPPKGCDVSGLVHDIDLLKDKVDAINVTDHQSSVMRFPS
IGGCLLVKEQGGEPVLQVTCRDRNRLALQAELLFAHSRDIHNVLCLTGDSVDVGDHKEAK
PVFDLDSVQLLRTARLMETGTDMSGNELKGAPQFCLGASVHPGADFIEPQLIKFDKKVEA
GAKFFQTQGVFDLASLRRFMQYASQFDVKILAGIIVMASARMARYMNDNVPGITVPQPVI
DELATAEKGKGLQKGVEIAARFVKTIKEEKLCHGVHIMAVGNEKIVPDILERAELISVGA
>A0A2E7HYM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIIDILSDKQTISFEFFPPRRAEGIPDVVXKMKMLSAYTPDFISVTYGAGGSTQGFTEE
LSRIAKADLNLEVMSHITCVGQTTEEIDHILSRLKSSNIDNIIGLRGXPPKGSXKFIPTV
GGFQYASELINHINNXFEFCVAAAAYPESHTESTSIDTDIEHLKEKVDMGVDFLITQXFF
DNXYYFNFVERARKAGIQIPIIPALLPILNASQIRRFTTLCGASIPEQLNNKLTKIEDDD
DQVIQLGIXYASQQAENLLSNKVPGVHFYVLNKNYSVQKILKNLNLVPH
>A0A0P0USX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|endosymbiont of Bathymodiolus septemdierum str. Myojin knoll|TrEMBL
MKTSFEFFPPRTEKGQKTLAQVRQELSAIQPEYFSVTFGAGGTTQEATLETVLDIQKNDS
IPAAPHLSCIGSKKDEVIALLDQYKKANINRIVTLRGDVPSGMRDIGDFHYANELVEFIK
TQYNDHFHIEVAAYPEMHPQAKNIQADLQHFANKVSAGADAAITQYFYNADAYFRFVDEA
EKLGVDIPITPGIMPITNHTQLVRFSNMCGAEIPKWILERLRCYENDLEALSAFGTEVVT
DLCQTLKNQGVDSFHFYSMNRTQPSLDIAKTL
>A0A3N5QTR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPIFTPGRRWQPPFYPFKREPFGTRLLISIERMVKGPLFGCRMCGNCLLQETAFICPMEC
PKGVRNGPCGGSTPERCYVDETRPCMWYKIYDRAFRMGRQEILLEVLPPLDWEKTGGETW
GDVLHQVRKVGTGKVIRGLATTDVKRRVETWDSIFQPVRQPDWWEGDSKYHPPAYTEPVS
ELERRLKAGEFVVTSEVAPPMTVATNKLCKNLEIVKDFCVAVNFTDSPSASPRMSSWACS
SIAVQNGLEPVMQIAARDRTRIGLQGEVLGAAALGVKNILCLSGDSMKMSGTPRGRMDIV
DLDSVQMLWILRRMRDEGKYLDG
>A0A1Q4GE11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus sp. 63-78|TrEMBL
MTERTFSFEFFPPKTAEGAEKLRATREQLAQLDPRFFSVTFGAGGSTRDRTLEAVRDIQA
AGSEAAPHLSCIGSTEASIRDILNEYKSQGIRHLVALRGDLPSGSMDVGEFHYANELVAF
IRKETGDWFEIEVAAYPEVHPQARSHTEDLANFKRKVDAGADSAITQYFFNADAYFNFVE
DARALGVGIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLESYGDDLASIRAFGLDV
VTDLCGRLLTGGAPGLHFYTMNQAGPSTTIWQRLGL
>A0A094AT43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4281|TrEMBL
MHIKDSLKQGEQAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHA
QLTCEMVSVAQSVYGLETCMHLTCTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEK
WVATDEGFQYARDLVRYIRKTYGNHFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATF
IVTQMFYDVPNFLDWVKKVRAKGITIPIIPGIMPISTYASFLRRCNHMNARIPPGWIEAM
EPVKNDDAAVREIGKGLVTEMCRAIIDSGINHLHFYTMNLAQATRGVLEQLDLLPSEERP
LKQALPWRQSLGLGRRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGEPKSVKDIANVFLRYLNADIESLPWSEAPISNEADVIKSQLVE
LNERGLLTINSQPAVDGVKSSHPVYGWGPQSGYVYQKAYLELLVAPELIDQLLDRIAGDP
EVTYYAVTKSGTLRTNAPSDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHDASSPSRNVIQRVMETFYLVNIVHNDFRQREALFSLFEGLAVPNIDQPAEGIAVST
PVPTPAAAAAPATNGDKVEDVPSAIVSNVLPVA
>A0A2E9GK04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKKFSIEILPKQKDKIPDINKKYFNDVYITHIPGSPLKDLIETSEAVLNNNLNPVPHLPA
RSMESENDLNFLLNKLTKLGVSDILMIGGSSKNVLGPYSSTASIIKSGILNKYNFKNIRI
AGHPEGNPDDKNTEESLNEKLKLLSNNFKISIVTQFSLSASITNDWIKKTRKLTDEIDDT
EIIIGLAGPSKITTLMKYAKVCGVNASASFLKKQGFDITKLIKHSPDDILNKLKNYDAIH
FFPFGGIKELNLWADNYSEAK
>A0A536MQC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSPSRLAGLLRDGHFVVTAELSSSNSADPQATWRRAEVLRGSVDAINCTDNTGAHVHMS
SLAAAHLLVEKGLEPIMQLTVRDRNRLALQADLLGAAALGVRNLVLMSGDDVTAGDHPEA
RRIYDIDSMQLLEVAAAMRDRGTYLSGRKLEQAPSFFIGAVENPFAPPLEFRPLRLQKKV
RAGADFIQTQLVFDVPVFTRFMDMVGELDLQKKVFIIPSIGIPRSARGARFMQQKVPGLH
VPESLVSRLERTAPARQAEEGIQIAVELVRAVREIPGIAGVHLIGIKWEEGVVQVAERAG
LLPRPTLSPLAAIGIVHSPAGGGQGGGVP
>A0A1F3FN20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWE2_29_8|TrEMBL
MKLIDVINKSKTPYISFEILPPLKGQSIDKLFSILDVLMQFSPPFINVTYHRSEFVYKEK
AGGIFEKVAVRKRPGTVGICSAIMHRYQTDSVAHIICGGFSKQETEDALIDLDFLGVKNI
LALRGDPAKNEKHFEPEIDGHSYAIDLVKQIVNMNKGIYLDEDLKNAINTDFCVGVAGYP
EKHYEAANYQSDLRFLKAKVDAGADYIVTQMFFDNQKYFKFVDDCRAIGINIPIIPGIKT
ITNKKQIYSIPKIFHIDIPDDLYKDIFNSKDDKTVCEIGCDWSIEQSKELIKYGVPCLHY
YTMSNPEPIVKIIRKVF
>A0A2E2YNZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MCTSYLIFFDHLLRCTYEWEKSLTLIADLLSQDTTFSFEFYPPRSEKGTKQLMTTMEHLL
PYNPSFISVTYGAGGSSRQQTLDIVKELKHNTRSTILPHLTCIGHTRNEIKSLINQYIDI
GITDILALHGDQPKDSVALPEGDFRFATELIDFLRTNYDLTLGVAAHTEGHPAASTRLND
LDHQSSKIRAADFAITQFFFDIDHYISFCNEMEKRNVGTPIIPGIIPVTNPAEVNRMIEL
AGGTFPKKLWEEINSARNQEERQFVGVNYAVQLIKQLLSAGAPGIHIYPMNRWQATEELL
EHLGFSPH
>A0A2U3QIG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfobium mesophilum|TrEMBL
MIIGSQKPIDEIWSMVKDFKKVLVFACNTCVAICHAGGEKEAETIATLLRMRAGQEGKSM
EVNFASVVRHCEPEYFEPVMEELQKYDLILSTACGVGVNFLSDRTGKIPVYPGINTSFYG
AVESPGNFVELCAGCGNCILHLTGGICPIARCSKTLMNGPCGGTNKGKCEISPDVDCAWY
LIVERMKKLGNLEKLAEIQPPRNWSTSRDGGPRRVSLEHIRAYEEQEELKSETAGGKK
>A0A2E7PE22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAFEATGKTSFICDFSPPRSGDPQIVDQAQIDVDLISVAYNPGRAVRTNSAMLAAAIKRS
GKESVFTLATRDMNKLAVQSQLLGAQMLGVQNVIVVQGDPFNEKDRTMVSPVNDYRPTRL
ISAIAELNAGRDFRGGQLRSPTDFCIGATIDLGRGIEEEAQLAVRKVQAGAEFLITQPIF
NVDAVARYRESYGYHAGKAGTFPIYFGLQILEKNGVLFSSVPDSVREELEGGRSGVDIA
>A0A536RBW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLHRGRPTISFEFMAPRDESEVEVLERTVAALAGHAPDWVSVTYRVRTGDKTLEL
VTRIKRHYHVEAMAHLTCANSTDRTRQILNWMEREGVANVLALRGDPPTSGEPFSPVDPE
LTHASDLISLVRRSGYRFGIGAACSTEKHPESPDLDHEFRYMQLKVESGADFLITQLFFD
NRFYFDLVARARGAGIKVPIVPGLMPVPSRRSLSVMTSMSGATVPATLQGAIDAAQDDEA
IRVLGVQHCIAQCTELLEAGVPGLHFYTFNRARAPMEILAALRGQQLIAS
>A0A2E3DXU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGFIQEIEETEEKFGNVFITDISPPKGINKISYEPIININSDFLLIIDSPGGSVRSAPIP
FAYKLSVEENQNVIFTMNCRDMNKLAIQSNLLGAQMLDLHNVFIVNGDDSTKHKQSXKPV
NDYTTTSLISDIVNLNLGIDFQKXKLASXTTFTVGSAIDFSKVPQINEIKLVRKKIXNGT
DFFISQPCYDQSLILDFHKAYYSQYGYRLEKPIFYGVQMLSRTGRNWGFIPEHVKNEMKS
NVSSLEIALKFVQQLLXLGLNKIYLVPPIENGGNRDYGMAQLLXKXIRSM
>A0A1V5JWG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium ADurb.Bin510|TrEMBL
MLIRDILNRHSPSFSFEFFPPKTDEGSLKLFKTIQELMPLKPSSVSVTYGAGGSTRDRTH
DLVLKIQKETGLTVVSHLTCVKSSRSEIEEILRRYDASGIHNILALRGDAPPGEDWSCGP
DGFEHAADLVAFIKQHFPHMGVGVAGFPEGHPGTPNRLKEIEYLKAKVDAGADYIVTQLF
FDNRDFYDFCERCELAGIHVPIIAGIMPIASLANMIRMAELSAGSRIPATLQRAIYRAGS
DEKVEQVGIHWASEQIRDLIDHGVKGIHIYTLNNSKAALQIYKHLGADDSDDLAK
>A0A535XSE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGALANLLRSGEFLVTAELNPPKNAAAGVVRRRAEALRGVVDAVNVTDSNRAMVQMAAIP
AATIVRSAGLEPIVQMTGRDRNRIALQADVLGAAAIGIENFVFMSGDDPKLGNHPDAVNV
KDLDGVGLVKMAVGMRDEARFLSGDEIKPALPKMLIGATASPFTKPMEADVKKTFDKIAA
GAEFLQTQPVFDLPTFSRWLVEVRRGTSREVPIIAGVLILRSPEQAERLAKVPGLSFGPD
AIDRMKGAADPEAEGIAIAVEMVKSLRSLPGVRGVHLYAIEWPEAVGRVVEASGLLPRPE
VKVAV
>A0A497AA70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTRLRQELQSGKFVVTGEVGPPKGVGLDKCLHNAEMLRNHVTAINVTDLQSAVMRIGSLA
VSAKLVQRGLEPVYQLTCRDRNRLALQSDLLSAWALGIENVLCLTGDHPILGDHAETKPV
YDLDSVHLLKAASSLNQGYDMAGHELESAPSFFLGAVVTPGAEPVEPQIIKMKKKIEAGA
MFFQTQAIYEPEKFERFMNQVHGLKVPVIGGVVVLKSAAMAKFMNENVAGINVPEAIIQE
MEETKKEDRKKKAVEITARIIRQIRPFCQGVHIMPLGWDELVPEIIREAELG
>A0A2E5Q144|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSIFPSQSNLIEDLRNSRRNCFIACDFSPPKLDNPQGLKLATSLNPDMFSVSYNPGQSVK
LNPIFASFWIQNETKISSAFTLATGNMNPRCLEKLLLNAHVLGLTNAVFVMGDSSSKTIS
ATKALELTARMNFGLGVGNNQLDTPTNFCIGSTIDISKNWDHEILLTKKKIDSGAEFFLA
QAQFDISKVIQFLESYRDKIGTHIEVPILWGVQMITKGSSSFTTIPDDMKRDLDLGRSGL
DIALEIFDQYFVYGIDSFYLLPPFFRTGKRDYALAEELISALTSN
>A0A257EL67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium PA4|TrEMBL
MADPAAPQFADLPGDIAVSFEFFPPKTPVMEATLWESVETLAPLAPRFVSVTYGAGGSTR
ERTHATVARIVRDTAIPAAAHLTCVDASRDEIDAIARAYWQAGVRHIVALRGDPPAKGAK
FEARPDGYASAAELVAGLKRVADFELSVSAYPEVHPEAASAASDLDALRAKLDAGASRAI
TQFFFEPDTFLRFRDRVAAAGIAAEIVPGILPVSNFANLRRMAEPCGTAIPGWMARLFEG
LDDKPAARQLVAATVAAEQCRRLYDGGVRHFHFYTLNRAELSYAICHMLGLRPALEDLAA
>A0A3N5S4U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
IRAMRDALDHPVRPHHLSAIAAADAPDAAVSDAPEQPTQMARKLAAGKFVVTVEMPPPRS
YTAQKVIAAAELLREAGVDFINVSDSPMARMRMSPWAVCHLLQDRVGLETVLHFPTRGRN
LLRVQGDLLAAHALNVRNVFVVMGDPTVIGDYPDSFDTHDIVPTSLIRLIKQNLNQGIDQ
AGNSIGQPTSFQVGCALNVNALDLDREIDLLRKKMAAGADFALTQPIFDPAVLDHFLQVY
AERHGPLKLPVLAGILPLYGARHAAFLHNEVPGINIPETIRQRIAEAGDDAPQEGVLVAQ
ELLTGIQDMAQGVYIMPAFGRYDLVAGVVDILGVSQAARP
>A0A836YVY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei EFB6|TrEMBL
MRKQTFSVEIEANPGDLRQMKHYLHKWQPDFVSISNLSRYSYEEMVQCARYIQTDLHIPV
VIHLTGLTHTKEQIKKAFNELMGLNIRNFLLVRGNIHHNMHIEDDFNYASDLIKYVNQLD
TDSKINVFAGCYPDIHVLADSLTEDIEYLKQKVNSGVDSLISLMCFDNKRIYKFLDKSRE
YGINIPIRIGIMPITDQFKKHYLAHNDVKMPELSEEEDNLLENGIDYAVNQINDLYQHDV
NGIHLYTHNDWMVSDRIFENIKQNL
>A0A089HNH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus durus|TrEMBL
MKLDLRSAWAAKVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEEVHRSYIEAGAEL
LESNTYSANYDKLSKFGLESKVEEINRAGIRIARKAAGSAGYVVGAVGSIRAGKRASLSA
SELKKYFGQQIGAMLEEDVDGILLETFYDLEELHLALRTARKLSNLPVICQFAVDETAMT
MDGLTLPEAFRILEDDGADVIGFNCRTGPIGIKRALGTLQGKLTLPVSVYPNAGLADYVD
GHYKYGASPEYFGEMASAFADMGCRIIGGCCGTTPQHIAEISAALTGYEPLPLPEPVTRE
KISVRIQESLADDSFADGGETTIIDLVKERHTVIVELDPPRDLDISKFMKGAEALRRAGA
DALTLADNSLAVTRMCNMALGSLVQQKTGLRPLVHIACRDRNLIGTQSHLMGLDALRIDH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKALKQKAKFVIGAAFNP
NVKHLGKAVERLEKKIAFGADYIMTQPVYDKELIHTIADRTAHLNIPIFIGIMPLASGRN
AEYLHNEVPGIQLSEEVRSRMKGLEGEAGRAEGVAIAKELLDAATERFNGIYLMTPFMFY
DMSVQLMEHVWAKSGRQLSPLFR
>A0A7K3TH02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium avesanii|TrEMBL
MTTPMFSLEVFPPKRNAPVGTIYDTLDGLEDLKPDFISVTYGHGTAADRTATARIAHTIR
SEYGIPTVAHLTALYSDHEVIDRALEMFDEAGVEAVLALRGDELPGARVGVFPHASDLVA
YIREKRPELKIFGACYPEGHYESKSLDEDIANLKTKVDAGASHLISQLFYDNDDFYRFLD
KARAAGIDVPIEAGIMPVRGAKSVRRMAERNASRIPARLAALLDKWADNPEALRAAGINY
ASEQITDLVAHGVDGIHLYTMNHPAGTRRIWHNVGPLFTR
>R7BJI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:882|TrEMBL
MNLHEYLKTHTIITDGAFGTYYAEKYGTSELPELANTEHPERVLEIHLEYLAAGASYIRT
NTYATNSRMLSENENEVMENLDAAVKAAREAVSLSKRSDPIFIAGDIGPIPGMAGMEKIE
NEQEYIRLADILLKLGVDAVHFETFADCEEIEPAIKYIREQSENVFISVCFSVNQYGYST
AGLSAKRLVADISKLPVDAVGLNCGVGAGHMEQLIGNLSLPSDKYFAALANAGYPDFTRN
RMHFGNAPIYFAGKMREIAHLGVSMVGGCCGTKPDTIKAVADAMADELLHEPADMAGQPK
KFNSDVTDGTAKKKRAGFIYDENGNVKDKKFIAVELAPPFDANDEKLLESAHALVGAGVD
VLTFPDSPSGRTRVDSVLMADKVHRETGIQVMPHICCRDKNAVAMRSLFMGARINDIYNM
LIITGDPLPSMVRETVKSVFNFDSVGLMRIAAEMNEETFTDRPLCYGGAINQGRRNLEVE
LARVKKKMDAGAQFFLTQPVFSEEDVERLRYIKRETGARILCGIMPLISRKNALFMKNEI
AGVNVPDELIEKYPENGSRKAGEQVGIELARNMIELSGDFADGYYFSFPFNRTYMLKEIL
KQQ
>L7U9T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8)|TrEMBL
MKIRNRLNPSNPCFSFEFFPPKTDEGVANLLKTLEDLAPLEPGFVSVTYGAGGSTRDRTL
ELVTRIKAETGIEAMAHLTCVGHTREELRELLQRLTEAKLDNVLVLRGDPPLGQKTFTPA
EGGFAYASELVQFIREEDFNFCMGGACYPEGHVETASRDDDLRHLKAKVDAGLDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYDQVQRFTRMCGATVPMRLGLQLERVKD
QPDAVVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRART
>A0A8B5F397|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. US24a|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A524KF39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MKQHIKNRIYHVEVLPPKQDTEKLDDDLAVFVTKFNRIMERGFCACITDNAMGNLAFQGT
EMIEELNIQAKPDLVMIHLNTFHSKDNLDGILESCRKIGIRQLLVVTGDGSDRLPKLKPA
DIGAKGVESVSSVELLRYIIGRWPGEFELGVAFNPYEPEEHEFAKFERKLAAGATFVITQ
PVIERHPLVDKLHALHPEVPMIVEAWMSKKLDLLSEAVGYDIPQCAPYDPIANLKTLHRN
YIDCGVYLSIIGFKTQFDLLKTTWETGAIS
>A0A522ZWP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinobacteraceae bacterium|TrEMBL
MTFPDTELSFSFELFPPRTPAGVAKLPAVVAQLSRLDPAYFSVTYGAGGSTQTGTYETLM
QVAEHTGVPVAAHLTCVGSTRVGIRALLDQYRTSGIRRIVALRGDLPATAAGSEAPGEFH
YAADLVRFVRETHGDHFTIEVAAYPEMHPQATDPDADFQHFCDKMQAGADGAVTQYFYTA
GSYFHFVERACRAGVKASIVPGIMPITNGPQLLRFSAACGADVPRWIRLRLEHYGEDRES
VQAFGLDVVTRLCNELLDGGAPGLHVYTLNQSAAALALWRSLGLAVPDPD
>A0A0K6HMC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pannonibacter indicus|TrEMBL
MSTSTDARRSHSSESAPVKVSFEFFPPKTDKMEATLWSTIQKLETLSPSFVSVTYGAGGS
TRERTHHTVERILKETPMLPAAHLTCVGASRAEVDAVVQDYWDLGVRHLVALRGDPQQGI
GTAYVPREDGYAYASDLVAGIKAIGDFEVSVSGYPERHPESKDWQTEIDNLKRKIDAGAS
RVITQYFFDNNLFEAYLERIAKAGLSIPVVPGILPILNFDQVVKFSSGCGTTIPDWLSRR
FAGLDDDAETRKLVGAAVAYEQVMDLVDRGISDFHFYTMNRAELTFALCHMLGLGQGETA
RQVA
>A0A014FER8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_2|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A1I6I1X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomicrospira sp. ALE5|TrEMBL
MKSQQQYPQGFSLECFPPRTAEGSDKLNQVIDELSVLNPEYISVTYGAGGTTQEKTLETV
THIQQNTRFDAVPHLTCIGATKDSIRALLKTYQDLGIKRIVALRGDMPSGMMDPGEFKYA
ADLVAFIRQETGDQFILEVAAYPETHPQARNCDQGIKHFKHKVDQGADAAITQYFFNADS
YFYFIDSCEKAGIDLPIVPGIMPITNYEQLIRFSAMCGAEVPRWLKCRLESFDEDTAGLR
AFGQDYVTRLCQRLLDNGAPGLHFYSMNKTQPTLDIVRDLNWRNDNMQL
>A0A0K9T5S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli M114|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1Y2LRX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epicoccum nigrum|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTAMGFANLQSRLERMSQALRPLFVTVTWGAGGST
AQKSLELAEICQRQLGLTTCLHLTCTNMDRALVDEALEQAKVLGIRNILALRGDAPRSEE
YRDEDKLPEQDSNKDFTWAIDLVKYIRKQYGDYFCVGVAAYPEGHSDESHPEHQNPSYDI
PHLVEKTQAGADFIMTQLFYDVEKYDKFETMLREHESGAFKTIPIIPGLMPIQSYSILRR
TTKLSHANLPVDLLARLDAVKADDEMVKKVGVKILGEMVEHVKARPDVTKRGFHFYTLNL
EKAVSHILEDTHLIGLLPADDEDAIETTPAINLEPPNDVPSARQRRRLSSISSPHNRVIR
DHLSASRSNQSWETSDTEAGIPRGPVNTRANTLAISEGEGSLGREATWDDFPNGRWGDAR
SPAFGEIDGYGPTLHVSNVTALKLWGHPVAQEDISNLFKRHVEGTLEALPWSEQTLSEET
KVIAPQLLALNAKGWWTVASQPAVNSVRSTDPVFGWGPKNGYVFQKPFVEFFIPSTDFAK
LKPRLDEHEQITYFAGNAAGDFEAKQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWRDE
AFSIWKEWQRIYPTKSATGKLLRETRNDVWLVNVIWGDYVEGDGLWEFLGA
>A0A356NEU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. UBA8638|TrEMBL
MKSQVSPSAFQQALAGGQPVITAEISPPRGGSVQHVLTTADRLRGRVHALNVTDGSRAVM
GMSSMAVCRLLLERNLEPVLQMGCRDRNRIALQADLLGAHALGLRNVLCLTGDPVKAGDQ
PGARPVFDYEAVRLLRDVKNLNRGLDALAQPLPDGPTALFPGCAADPQLPSWNGLKRRLK
RKKEAGARFIQTQMVTDLAALRRFCRELAAPLALPVLAGVFLLKSGKNARFINRMVPGAS
IPDAAIARLDAARTPRAEGLRMAAEQVAAALEIAQGVHIMAIKAESSIPQILDLAGVPPL
APAIVGSVVPRSLAAEPR
>A0A016VGY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylostoma ceylanicum|TrEMBL
MDTPGGSVPNLHERSSSDEEHLSFEVGHGNKYVPLHERINRRIKDKTPFFSLEFFPPKTA
NGVANFFTRLDRFNEGGPLFVDITWHLGSDPANMNKETSSSSIAAGCLDYCRVDTMLHMT
CAQYSKEQTIKHLEQSKSVGLRNILALRGDLPNIDADGIPIYKYRALDMIRWIREEFGDY
FTIACSVDCYFTGYPLGHPESPSYKADLLYLKSKCDAGAQFIVTQLFFEAEVFEQFVRDC
REMGITVPIIPGIMPIMGYDSIRRIATLSQLTIPESILSDLEPIKHDDDAVRKYGTIKAI
EMCRRILSNGSAPSIHLYTMNREGACREILQELGLWHKRPMRALPWEPHGSNHPLRCKED
VRPIFWSARPKSYIYRTRDWDDFPNGRWGNSSSPAFGDLQDYYLFHLKAQTKKEDLLKMY
GEELLSFDDVKKVFTNFISQGVNENGVKVTTLPWNEQDVGVQAETKLINEQLLWCNENGI
LTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFISKENAISLLEIVDDYYPRINYH
IINHDGSFDHMNGEATTPIAVTWGVFPGAEIAQPTVVDPLAFRAWKDEAYDTWIKNWANL
YPKDSISRNVIQKIHDDFCLLNVVDNDFQKPVIIYEILEKMLKRTEERKASA
>K9T4L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pleurocapsa sp. PCC 7327|TrEMBL
MTTRFRRAVQDREFLITAEVTPPKGGNPVRMLEMAKLLKDRVHALNITDGSRAVVRMSSI
AASVILLQHGIEPICQIACRDRNCIGLEADLMGAHALGIRTILALTGDPVKAGDRKESRS
VFELESVRLLKLIANLNSGLDFKNQPLPDEPLDLFAGAAVDPQLKSWSSLQQRFDRKVEA
GAQFFQSQLITDFERLDKFMNQIAAGSNKPILAGIFLLKSAKNAQFINKNVPGVQIPEDI
IKRLADAPDPLQEGVNIAAEQVRLAKQVCQGVHLMAVKREDLIPQILDLAGIPPIEKPEL
NCV
>A0A7X0MC63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium lusitanum|TrEMBL
MAQIDENPLGAGLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
SGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQGDVLGAAAMG
VCNILCLTGDGVQVGDQPGAKPVFDLDSMSLLEAVRTMRDEAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPHRLAKKIEAGAQFVQSQYCYDVPMLRDYMKKVRDLGLHEKCFILVGV
GPLASARTARWMRTNVPGVHIPDDVIRRIEGASDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEIVHDSGVLRGRRPWKHEAGRSDALVAERLGHIREGEEENQLAMVEAAS
HPQPRKADRD
>A0A6L6TBK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. TDA1|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKEELRSLLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEIDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLAIWNNLKLPR
>A0A7Y8Y7H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium agri|TrEMBL
MKVTEHIQNANGKTLFSFEILPPLKGQNIQSIFDGIDPLMEFNPPFIDVTYHREEYEFKE
LDNGLLQKKVVKKRPGTVGICAAIQNKYQVDAVPHVLCGGFTKEDTENLLIDLDFLGIEN
VVALRGDAIKSEIYFKAENEGHHYASELVSQISNLNSGIYLDSDLKNVNTTNFCIGVAAY
PEKHMEAPSLDSDIYFLKQKIKNGADYIVTQMFFDNKKFFDFVDKCRANGITVPIIPGLK
PIATKKQLNQIPHRFSVDLPDDLIMAVVKAKDNDAIKQIGIEWCIEQSRELIKAGIPVLH
YYSMGKAENIKAIARAVF
>A0A4Y3G6T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|cyanobiont of Ornithocercus magnificus|TrEMBL
MQASPLSSALQRAFTSGTSTITAEVMPPRGGDPARTLAMASGLRGWVHAVNVTDGSRAVM
RMCSLAVCRLLLDIGIEPVLQLACRDRNRIALQADLLGAHALGIRNLLCLTGDPVQAGDQ
LKARAVHDYESVRLLEQVSAFNRGEDPVNNCLAEGSTALFAGAAADPNNRNLSSLHRRLE
RKRNAGARFLQTQMVMDPAILEHFQTKLAGPLELPVLAGVFLLKSARNARFINQMVPGAC
VPESLITRLENSSHPSYEGITIAAEQVRRYRDICAGVHVMAVRAEDKIPEILDRAGVSPV
LL
>A0A5C6M0N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga pinensis|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIDSIYDHLDPLMEFKPAFVNVTYHRSEHMFKKR
ADGSFEKVEIRKRPGTVAICAALMGHYNVDAVPHLICGGFSREETENALIDLNYLGVDNV
LVLRGDAPKNETFFEPEPNGHRYADELLQQVVHMNNGIYLEEDLQSGVKTKFCIGVAGYP
EKHFEAPNMQTDMSYLKKKVENGADYIVTQMFFDNQKFIDFVGKCREAGITVPIIPGLKP
ITTRKQLTILPRTFHVDIPTDLSTEILKCKTDKEVEEVGTEWLIKQSRELKQFGVPVLHY
YTLGKPHVIRKAVAEVV
>A0A552FE73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa Ma_QC_Ch_20071001_S25D|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDAAGIPPIHN
>A0A2S9YXK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enhygromyxa salina|TrEMBL
MGAVLGACYWGDGMLIRDRLAHKRPVFSFEFFPPNNEKGERVLWRSLEQLAPLEPDFVSV
TYGAGGSTRTRTVEIVGRIKRELGIEPLAHLTCVGSTRDEIEAVVERLLEAGVRNILALR
GDPPRGQTQFEHTPGGFRYASELCAWLRDRWPELCVGGACYPEIHPEAESDEADLRHLRA
KVDAGAEFLISQLFFDNAAYFGFIDRVRGAGISVPIIPGVMPITNVKQIERFTKMCGASI
PNMLRSRLHGIAETTDGYDPQEVFWTGVSYAAHQCRELLDPPSRGPFRRQTSTVAGIHFY
TLNRSPATRALFEILALARAVH
>A0A542LVK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. SJZ107|TrEMBL
MMETPNLSIEFFPPKTPEGADKLRVARQKLAELNPKYFSVTFGAGGSTQQGTLATVLEIQ
AEGHEGAPHLSCVGATRASIRAILQEFQAKNVRRLVALRGDLPSGYGGAGELRYASELVE
FIRAETGDWFHIEVAAYPEMHPQAKSPQDDLQNFARKVQAGANAAITQYFYNPDAYFQFV
DNVHKLGVDVPIVAGIMPITNYTQLMRFSEMCGAEIPRWIRLKLASFGDDSASIKAFGLD
VVSSLCERLLAGGAPGLHFYSMNQAAATTAIWQRLQSA
>A0A5C8ZHC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Quadrisphaera sp. DD2A|TrEMBL
MTGKDVEKLDEARSALPAGTRINVTYLANEDLPMRVAASAAVKDWGFVPVPHVSARRLAS
QAQLEEFLTELQRVGATEELFVVGGDPATPEGPYEDSLAVIRSGLLQRYGVQRVSVSGYP
EGHPDIGDPVLWQALEGKHAALREQQLPGTVITQFGFDADAVLTYLAAVRARGVDLPVRV
GVPGPAGIKRLLGYAKRFGVGTSAGIAKKYGLSLTNLLGTAGPDRFLEAVAAQLDPAVHG
EVKLHLYTFGGLRATAEWAQQFRATHP
>A0A2T2QQQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. MOS002|TrEMBL
MTDVTMPAHTDGHLKRPAISFEFFPPKTEDMERNLWDTINRLAPLDPKFVSVTYGAGGST
RERTHATISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPAGGIG
TPYASHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDDDIDTLQAKVDAGAT
RAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARAFVTRTGTTVPDWLAEK
FEGLDNDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAKSAQ
KAA
>A0A0M8RKJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL F-5755|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLAELRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVQHPEGVLYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATQLCARLMAEGSPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A169ZM94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya valderiana BDU 20041|TrEMBL
MTCFRNAIESKQFLITAEVAPPKGGNPAHMVEMARGLKNRVHAVNITDGSRAVLRMSSLA
ASAILLQQGIEPICQIACRDRNRIGLQADLMGAHGLGIRTILALTGDPVKAGDHPGAKSV
FDMESVRLLRLIHKLNRGIDFNDKPLTDGKTDLFPGAAVDPQSKSWSGLQRRFEKKIEAG
AQFFQSQLISDFDRLDKFVTQIASAYNKPILAGIFLIKSAKNAQFLNKKVPGVQISQEII
DRLDRASDPLREGMAIAAEQVRLARDLCHGVHMMAIRSEHLIPEILDMAGVEPIESL
>A0A4U8UQ34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steinernema carpocapsae|TrEMBL
MVLDTTVTIENGFTTGASVKGIAHANEYVPLHQRIEKHIASGTPFFSLEFFPPKTVNGVA
NFFTRLDRLREGGPLFVDITWHLGSDPANKNKETSSTSIASACLDLCRLDTMLHLTCAQY
TKQQTLEHLNQCKSLGLRNVFALRGDLPKHDNNPVVYQHRALDLIKWIRKEHGDHFSIGA
SGYPSGHPEAESYQHDLLYLKAKVDAGAQFVITQLFFDADVFERFVHDCRAIGITVPIIP
GIMPIQGYESIRRIADLSNLTIPDIIMKTLEPIKHDDEAVRNYGTYLATQMCRQILNNGT
APSLHIYTMNREGNCREILQNLGLWMQQPQRSLPWMPHGGHHPIRCKEDVRPIFWSARPK
SYIFRTKDWDQYPNGRWGNSSSPAFNDLQDYYLFYLKGTPTDDHMLDMYGRQLNSVDDVR
KVFVNFITQEENENRVKVTRLPWNEQESGTLPETTLIQEQLLWCNKNGIFTINSQPAVNG
APSADPIVGWGKPGGYCYQKAYLEFFIEKAKAEQLKKVIEKEGYSHLSYHMINYNSTVEW
TNGDSTTPIAVTWGVFPGCEIAQPTVVDPLSFRVWKDEAYDAWLSTWAAIYPEGSISTKI
LQEVHDNYYLVTVVDNDYVKDTVIFEALAKAVEP
>A0A1B8WAV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. FJAT-26390|TrEMBL
MKQGDYAVRISLELVPRDSEGLRAELQCVKAEFPSINTINIPDLTRFELRSWEASSLSKS
YYEDCIPHIRSMDFDAREPFSLIEYLDAHQLSEVLIVTGDAPKNSSQPVYPTTCIDLIAK
LKREHPHLKIYSAIDPYRNSIRKEYEYVQQKLNAGVDGFFTQPFFDLRFMELYSEMLAGS
DIFWGVSPVVAESSKRYWETRNHVVFPKDFEPTLEWNVEFSKKALAYTKQMNSHIYFMPI
KVDLRAYFDGVFGKALTNSLK
>A0A7Y6MAY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea rhodomycinica|TrEMBL
MALGRPSVLPDRVPTVRELLASGGRSFSFEFFPPKTDEGERQLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERVAHDTTLTPVAHFTAVNHSTRELRHLVGRFADAGVRNILAVR
GDPPGDPTGEWVRHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIDSDTEFFVR
KCRAGADYAITQMFFEADDYLRLRDRVAARGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPALAARFEAVADDPAAVRQLGIEHGAELCQRLLDEGAPGIHFITFNRSSASREVFQLLS
RPEPVAV
>A0A6J7KTI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MKKIGEGVTYSFEFFPPKDPEGEERLWSAMGALEPIAPDFISVTYGAGGTTRDRTIRITS
EITQRTHIPTVAHLTCVGSTRDELIEILGRYKQAGIHNILALRGDPTGGPRAPWTPTPGG
LNHADELVTLAAEVGGFTIGVAAFPDGHPASGLDFAEDIEVLLRKEEAGASFATTQFFFE
ADKWKALVDRLAARGSKLPIIAGILPVSNVNQLNRMAELSGVPIPTSIADRFAALKESPE
DVKKLGVEIATQLCEDLLTAGVPGLHFYTMNTSSATREIFEQIKDKKRG
>A0A8E1VSG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. K32|TrEMBL
MTSLSFEFYPPKTDEQRSQLDRTAAKLRSFRPEYVSCTFGAGGSTLSYTSETVRHLKQHH
RFEAAPHLSCVGGSRQEIRELLKLYRAIGCSRIVALRGDLPSGMGHPGDLRYAAELIDFI
RAEHGNAFRIEVGAYPETHPQASDALADLKHFKAKVDAGADAAITQYFYNADAYFHFVDA
VRALGVSVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGRKMQAYGDDSESIRAFGAEVV
AQLCQRLVEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A6G9AMJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma aureum|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFVDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFSREETEDFLIDLHYLGID
NALVLRGDPAKPFSTFKAKENGYTYASELVEQVANMNRGIYLHEEDTPLASSNFCIGVAA
YPEKHFEAADHDIDFHYLRHKIDKGADYIVTQMFFDNQKYFDFVERCRHAGITVPIIPGL
KPISTRKQLQILPKLFHLHLPDDLVKAIEACENDQQARQVGIEWSIQQCRELIAHEAPVL
HFYTMGKADNIMKIAREVF
>A0A6J6FAP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTGIGESVTYSFEFFPPKDQEGEDRLWSAISALEPIAPDFISVTYGAGGSTRDRTIRITS
EITEHTKLPVVAHLTCVGSTREELIEILARYKSAGIHNILALRGDPTGGPRAPWTPTPGG
LNHADELVTLAAEVGGFTIGVAAFPDGHPASGLNLDQDIEVLLRKEKAGAAFATTQFFFE
ADKWKALVDRLAKRGSNLPIIAGILPVTNVNQLNRMAELSGVPIPAPMRDRFTALKDSPE
DVRKLGVEIATELCEDLLTAGVPGLHFYTMNTSSATREIFAQIKDKKRS
>A0A7Y5VFY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospiraceae bacterium|TrEMBL
MKVTEYFEKANGQTLISFEVLPPMKGGSMQAIFDTLDPLMEFKPPFIDVTYHREEFVYKK
RPSGYYEKTSIRKRPGTVGICAAIMHRYGVDAVPHLICGGFTTEDTENALIDLNFLNIKN
VLAIRGDARKFEGQFVPEDGGHHYALDLIRQIADMNKGKYLDDNIENGEKTDFCIGIAGY
PEKHYESPNLDLDLHYTKAKVDAGANYIVTQMFFDNKYYFDFVKRCREAGIEIPIVPGLK
PLTKLHQITSIPRLFHVDLPTELVSELLKASSPEARTQVGIEWCIAQSRELKASGAPCMH
YYTMGDTDTIRKIVKAVY
>A0A0G8CL11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFMGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2A7BYF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7Y2C0K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospiraceae bacterium|TrEMBL
MKVTDHIDRANDTLISYEVLPPLKGGRMQDIFDMLDPLMDYKPPFIDVTYHREEFIFNKR
ESGYYEKIAIRKRPGTVGICASLMHRYGVDAVPHLICGGFTKEETENALIDLNFLGINNV
LAIRGDARKFEDRFIPEEGGHSYAVDLIRQIEKMNKGQYLDPNLDNAAPTDFCIGVAGYP
EKHFESPNLDSDLKFLKEKIDAGGEYIVTQMFFDNSKYFNFVERCKAIGINVPIIPGLKP
ITFKSQLNSIPRKFFVNFKDELVAEMQKAESKEAIKQIGLEWCIEQSKELKAAGVPCIHY
YTMGDTETMQKILEAIA
>A0A401I4Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. 598K|TrEMBL
MKPDLREAVTRSLITGDGAMGTYLYQLGFPVGVSFEEFNTLRPEVIRNVHRAYYEAGARL
IETNTFSANYEKLSKYGLEGEVVKLNRAGVQLAREAVGEDAYVVGSIGSIRSGQRKTIRT
SELRKAFRTQIAALLESGVDGLIMETFFDLEELLLVLSLVREAGDIPTICQLSAEDVGRT
KDGVTLSEAFARLEAAGADVVGLNCRSGPVGILRALDTVQGDIGIPLSVFPNAGIPDYVD
GQYTYTAPPEYFGDMARKFADRGARLIGGCCGTTPEHCAAISGALQGYEPQPVEAEAELQ
SERLEVRSPEGGAGGAQEPPPKEPSLVDLVRQRHTVIVELDPPRDLDIRKFMAGAEALKA
VRADALTMADNSLAVTRMSNIALASLLQERTGIRPLVHIACRDRNLIGTQSHMMGLDALG
IDHVLAVTGDPARFGDLPGSSSVYDLTSFEMIRMIKQLNEGIAFSGKPLKQRADFVVGAA
FNPNVKYLEKAVQRLEKKISSGADYIMTQPVYDPRLIEEIAKATAHLPIPVFLGIMPLAS
GRNAEYLHNEVPGIQLSDEVRQRMHGLEGEQGRAEGVRIAKELLDSALPHFNGIYLMTPF
MFYEMSAELTEYVWVKTGRQQEILRG
>A0A7Y8JF58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MKPEISFEFFPPQTPEGLEKLRATRAKLAAAAPSFFSVTYGAGGSTRERTFDIVMEIAAE
GHAACPHLSCIGSTRAGIRKILADYRDRGIRRIVALRGDLPSGMADPGEFRYANELVEFI
RAETGDTFHIEVAAYPEWHPQAKSPRDDLLNFKRKVDAGANSAITQFFYNAEAYAHFVAE
ARALGVTIPIVPGIMPIGSFSKLARFADSSGAEIPRWMRKKFESFGDDADSIRAFGLDVV
TELCERLIALGAPGLHFYTLNQSALSLEILRRLGLV
>A0A2C4Q2A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVIDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGVRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A807ZKK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp. G11|TrEMBL
MHIGDSIRAAQKPFFSLEFFPPADEANLPAFFETVEQLRPLAPLFASVTYGAGGGKQRNT
LAVTAELARRGLNTMAHLTCVGADPESISTYLSELRAAGVDNVLALRGDPPAGEEWDWNS
GRFRHASDLVTFARRQQPYMGIGVAAYPAPHPESTSISQDRRHTADKMRSGADFAVTQLF
FDAREYADLLEHLRGQGIHTPVIPGILPIQSFASLRRVLALCGANIPGKLYLDLEKADEK
GGVEAVREVGLEFAVRQIRFLLDNGAPGVHLYTLNKADMCLRLAQESGLLGPDVNLPAA
>A0A7H0IK83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces roseirectus|TrEMBL
MALGTASTRTDRARTVRDILASGKTTYSFEFSAPKTPKGERNLWSALRRVEAAAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMAEWIAHPDGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSDHWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEIMPVTSVRMLERLPQLSNAVI
PSALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTASLEIYENLG
LHHPPRA
>A0A178C6E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fonsecaea multimorphosa|TrEMBL
MASEHDERLPTLLSSLPPSSYYFSLEFFPPKTSSGFSNLQARLARMATALRPLFVTVTWG
AGGSTATKSLELAEVCQRQIGLTTVLHLTCTNMRRHMIDEALEEAKEIGIRNILALRGDP
PREEYKDATSTDESESGSGGSGTESNQEFTWAADLVRYIRRKHGDYFAVGVAGYPEGHAD
ESHPEQGKQSVEHDLPYLAEKVAAGADFIMTQLTYDIEAYAAYEKRLRGYTGQDGKKLFD
KIPIIPGLMPIQSYQIIKRITKLSHAKLPEKISQRIERVKSDDEAVKKVGVDILSELVEE
MKTLPQPEAVPRGFHFYTLNLEKSVSFILERTGLIPAISSEGSVEDKDGDSESDSDVVVD
DSKQETPAIVTTGPVENGNQNGQQSSSFTRRRRSSVNAQPHNRVITDGRSEPRTQSRRPD
SDSDPPGLEPNPNLKLTSQHSARDRGTGIPAASPTRKHSLLISEGQGSLGREATWDDFPN
GRWGPSHSPAFGEIDGYGPSLKVSPLMARKLWGYPRSREDVTKLFRRHVLGDLVAVPWSD
DIDPDLASPGAASADGSGNSSALRAETDVIRSELLSLISSQNYWTLASQPAVDGAPSSDP
VFGWGPPGEGYVFQKAFVEFFCGRDEWEEKLRPRLMKYGSDVLGWMKTDAEGVFESSELI
ARDQARKKKAAAVDTEKENTNPASLVQFADQRPVPSASSSSPENTVNAVTWGVFPSREIL
TPTIIEAESFRAWAQEAYAIWNEWKRCFPRGSQEALFLEKMGKENVLVNVVGQSFRGGHG
GGKGEGASLWRILLAEDGDAK
>A0A6J7JU27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSDGRGLSMRDLLARGERSFSFEFFPPKDEAGEEQLWQAITDLEPYGPTFVSVTYGAGGT
TRDRTVAITERIARETSMLPVAHLTCVGHTVEELTTILDDLSRAGVHHVMALRGDPPSGP
GSPWTPTEGGLTYANELVALIRERADMRIGVAAFPEGHVDAVDLETDARVLKAKHDAGAE
FAVTDMVLRASDYIGLVERARAVGADLPIIPGIMPILNLRSMQRMVEFSRRQLPEEITSR
LEPLADEPERLRAEGIAIATELCRDLLEAGAPGLHFYTLNRSKATREIFANLRITV
>A0A6J7KJB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MIAELMTKSEPTLSFEFFPPKDESGEAALWSSFDSLLELSPDFVSVTYGAGGSNQAKSLA
VLTKMAARIPTIGHLTCVGATFPSTRATIGAFEDAGVAAILAIRGDAPRDNPDALSQGEL
KTALELVEQVTAHSEMEVGVAAFPELHPESPSLAHDVKVLKLKQEAGAKYAFTQLFFHVE
AYTALVAAARAADVTIPIIPGVMPIGNVKGVLRMAELSGASVPQELLIRLEGATDDENAK
DIGMAFSIEFAKALLAAGAPGLHIFSLNHHRAAEELARGAFSRLSR
>A0A6J6ET87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MALRGDPVGGPRAPWTPVDGGLTHADELITLAREQGDFTIGVAAFPDGHPNSEGNFDKDI
DVLLRKESLGASFATTQFFFEVDKWKRLVDALAKRGSTMPIIAGVLPVTNVKLLTKMAEL
GGTPIPDSIASRFAAVEDNPEDVRKLGVEIALNLCNDLIDAGVPGIHFYTMNSSTATSEI
FESLQDRR
>A0A6J6H0Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MKSGLTYSFEFFPPKDVEGEERLWAAMSALESIAPDFISVTYGAGGSTRDRTIRITSEIT
ARTHIPTVAHLTCVGSTRQELIEILGKYRSAGIKSILALRGDPTGGPRSPWSATPGGLNH
ADELVTLAAEFGGFTIGVAAFPDGHPASDGDIDKDVQVLLEKEKRGATFATTQFFFDAGK
WKTLVDKLEAQGSTLPIIPGILPVTNVKQLNRMAELSGVPIPSHISECFAKVEDNPEDVR
KLGVEIATKLCEDLLEAGAPGLHFYTMNTSSATREIYSQIKDER
>A0A7S7Q4P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. CCBAU 21365|TrEMBL
MTETISSVPNAPRAPKAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTITRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAGIKRRHADIEISVSAYPEKHPEAKDFDADIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A172ZIZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus bovis|TrEMBL
MKPDLRSRWTDGVIVGDGAMGTYLYQLGFPVGISYEELNLLSPHIIEDVHRQYVTAGAEM
LETNTFSANHEKLAKYGLEHKVEEINRAGVRIARQAAGDQAYVVGSVGAIREGKRSNTPL
PQLRKYFREQLNAILEEGVDGILLETFFELEELAVALKQVRKLTDIPVICQLTVEDAVRT
LDGYSLPDAFAILTEAGADMVGLNCRVGPNGTMRALEYVRGKVSLPLSVYPDAGVASYVD
GEYRYKAKPSYFGQSSVRLAELGARVIGGCCGTTPKHIAAIARALADYVPAPLDFSNVQV
PSPQISITMEKDILGGWGSDRDDVPPTLVELVKERPTVIVELDPPRDLDITGFMAGAEAL
KKAGADAVTMADNSLAVTRMSNMALAHLVQRETGLRPLVHVTCRDRNMIGNQSHMMGLNA
LGVDHILAVTGDPSKFGDLPGASSVYDMTSFDMIRMIKQLNEGIAFSGKVLKHRARFVVG
AAFNPNVKHLDKAVQRLEKKIAAGADYVMTQPVYDEHLIREMHEATKHLSVPVFIGIMPL
ASGRNAEYLHNEVPGIQLPDHIRGRMAGLEGPEARQTGVAIARELLDVALEYFNGIYIMT
PFMLYDMSAQLTEYVWAKAKQRPNPLFHGK
>A0A6J6VBB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MAKVGEAVTYSFEFFPPKDQEGEDRLWSAIAALEPIKPDFISVTYGAGGSTRDRTIRITS
EITEHTKLPVVAHLTCVGSTRDELLEILARYKDAGIHNILALRGDPTGGPRAPWSPTPGG
LNHADELVSLAADFGGFTIGVAAFPDGHPASNGDFAVDIDTLIRKEAAGATFATTQFFFE
VDKWKSLVDKLAARGSQLPIIAGILPVTNVNQLNRMSELSGTPIPGAMSDAFEKIKDKPD
DVRKLGVDLATKLCEDLLAAGVPGLHFYTMNTSTATREIFAQIKDKKRA
>A0A6J7P6G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MKYASELVDLIRGVGDFSIGVAAHPEPHPHSPSIEEDRRRTAEKLSKADFAVTQFFFDAR
HYFDLVESLHELGVDKPVIAGIMPATSMRSITRMSELQGSEFPKDLAAKLEAAEPDGPEA
VHRVGVEEATRLCRELLDGGAPGLHFFTLNRSMATREIYEALGL
>A0A178BML0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fonsecaea multimorphosa|TrEMBL
MHVSKKLELAHQQNKPTFSFEFFPPKTAQGVQNLYDRMDRMHNLGPTFIDITWGAGGRHS
QLTSEMVNATQNYYGLETCMHLTCTDMERHQVDEALRRAYKAGCTNILALRGDPPRDQEK
WEAKEGGFRYAKDLVKYIKARYSDHFDIGVAGYPEGCDDHRDVDLLIDHLREKVDAGASF
IVTQMFYDVDIFLDWVKKCRDRGISVPILPGIMPIQTYAAFLRRANWTKCHIPPGWFEAL
EPVKNDDAAVRAIGKDLVADMCRKILDSGIQHLHFYTMNLAQATRMVLEELSLTPETSGM
PLEKPLPWRQSLGFNRRDETVRPIFWRNRNASYISRTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNDANIKLWGKPRSLRDVTGLFVRFLQGDLDRLPWSEGGISAEADIIKDDLL
QLNKHGFLTINSQPAVDGASSTHPVYGWGPAGGWVYQKAYLELLVFPSMFETVMERLNAD
KNLTYYAVNRKGELYTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WAKCYPAGSGSRKLIEKIMDECYLVNIVNNDFHQNKEIFKVFEGLETKDLDLVLEDTAPS
HLENGAKDVSNGDAPPAGVGKGLTNGDQHKVPSKASGEVVLN
>A0A374TVS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. TF09-1AT|TrEMBL
MRVDEVFKQAASLGTVPVSFEMFPPKGELTLDTARKVAGSLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMIASEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A192A1T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia insidiosa|TrEMBL
MNDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILNTYRENGIRRIVALRGDMPSGMGEIGEFRYANELVEF
IRQETGDAFHIEVAAYPEYHPQARSPKHDLDNFARKVKAGANSAITQYFFNADAYFQFVA
DAHKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWVAKRLESFGDDRESIRAFGLDV
VTALCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A3N8CH03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Bp9131|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDNLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVE
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAAAATRTICERLSM
>A0A6I6MY26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terricaulis silvestris|TrEMBL
MSAHAPTLLANAAERVKRPSVSFEFFPPKSDALEATLWESIRKLEPLGPSFVSVTYGAGG
STRDRTHRTVARIVTDTSLKPAAHLTCVAASKAEVDGVLRDYWRAGVRRIVALRGDPPGG
VGMPYLQHPNGYASAVELVETAARIGNFDISVAVHPEKHPSSPSFDHDIETFKRKLGAGA
TRGISQFFFDENVFLRFRDRLARAGVYAPILPGIMPVTNVKGLKKMTDACGATLPRWMIQ
LFEGLDDDPETRRLVTAVTTAQLCARLSAEGVRDFHFYTLNRADLALAICRILGVRVKEA
VQ
>A0A8J2TD09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroococcus sp. FPU101|TrEMBL
MYTRFRQAIKNQEFLVTAEICPPKGGNPQHMVEMGTLLKNRVHAVNITDGSRAVMRMSSM
AASVILLQQGIEPICQMACRDRNIIALQADLMGAYALGIRNVLALTGDPVKAGDHREAKS
VFELESVRLLKLIQQLNHGLDFNEKTLPDEPLDLLAGAAVDPQCKSWSGLQSRFEKKITA
GAQFFQSQMITDFEQLDKFMNQIAVGVDKPILAGIFLLKSAKNAEFIRKNVPGVLIPDEL
IKRLAEAPDPLQEGVKIAAEQVKLAQQLCQGVHLMAVRREDLIPEVLDLAGIPPVNSIT
>A0A6F8TSC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. KH172YL63|TrEMBL
MKPLLDALKEKILIADGAIGTLLYSYGVDRCFEELNLSHPNEVVKVHREYIEAGADIIQT
NTYGANYQKLSRYGLEDSVKEINTAAVRLARKAAGQDTYVLGTVGGIRGIKQNVPLEEIK
RSFREQLYCLLLEGVDGLLLETYYDFEELTTVLKIAKREADIPVVAQVSLHETGVLQNGM
EVGEALKQLELLGADVAGINCRMGPFHMVNSLEEVPLPKTAFLSVYPNASLPNYEEGRFY
YSAEPGYFGDISNELRLQGARIIGGCCGTTPDHIRSVAEKLKSREPVTEKVVKRKKAVEI
SSPAIRGKLLHEQVKEKKTIIVELDPPKHLDTTLFFQGAKALKEAGIDALTLADNPLASP
RISNDAIGNLIHSKYDLTPLVHITCRDRNLIGLQSHLMGLHTLGIHNILAITGDPAKIGD
FPGAASVYDLSSLELIELIKQNNEGLSFSGKSLREKTRFSVGAAFNPNFRHLDASVKRLE
KKKKAGADYFISQPVFGRNQLMQIHEATKHLDIPIFIGIMPLISSRNAEFLHHEVPGINV
PEETRRRMKEAGADPVITRSVGMEMAKDLLETALELFNGIYLITPFVRYDMSIELIQHIQ
QLNAEREVPYGHHII
>A0A7D5UPJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium brunneum|TrEMBL
MHIKDMLAEAEKGGQPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLDKVNAALQKAYKAGCTNILALRGDPPRAQEK
WTAAEGGFHYARDLVKHIRATYGDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGKVRERGINIPILPGIMPIATYASFLRRAKHMQCKVPDHWMTAL
EPVKNDDVAVREIGKTLVAEMCRKLLANGIYHLHFYTMNLAQATRMLLEELTWAPCAERP
LQQALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTTVQDIAGIFVKYLNREMESLPWSEAPLTGEANAIKDNLIQ
LNKRGLLTINSQPAVDGVKSSHPIHGWGPSNGYVYQKAYLELLVPASIFTEMVKRVEDKP
TLTYYAVTKDGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGTDW
AHCFESETPSRVLLDQIMNEWYLVNVVNNDFHENQTIFDLFEGLEVKGLDTPVAV
>D4CWW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium periodonticum ATCC 33693|TrEMBL
MKIADIYKSKSLTTSFEVFPPNEKVGLEEVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHFTCIGSKKEEIDRVLEDLERNNIENILALRGDYPVDRKLEPGD
FNYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQIDVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A1Y3UWS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides uniformis|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNWKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A2E4EVT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MSTLSNALNSSEFVVTSELTPPKGLDLAPLLEKAALLKPYVSAINLTESHAARMAMDPVA
VGHLMLDQGVEPIVQMTSRDKNRLAIQASILGACALGXSNLVFMGGDPPKNGDHPDAKPV
FDLFASQLLEAVRAXNXGADXNGNTLNQHTEIFAGAVVNPGAXDPDAEIENLHRXIXGGA
EFFQTQAVYDVXAFXAFLEKANSPKPILAGIIPIXSVXMAQYMNERIPGVDIPXHLIXKI
AAAGEDKEAIVRISIEIAADTIRGLRSVTKGIHVMAIGWEQHIPAMLEQSQN
>A0A4Y8L3W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dysgonomonas capnocytophagoides|TrEMBL
MKVTDLITQNKGKTAFSFEILPPLKGNSIEKVYNIIDKLIEFDPKYINITTHHSENIYKN
MADGSVRKVNVRKRPGTVAIAAAIQNKYKVIAIPHMICKGFSKEETEYALIDLNFLGIHN
LLLLRGDANKLDAEQMVGNFNAHATDLQKQVNEFNQGISVDESTFDKFDTPFSYGMACYP
EKHEEAPNFESDLHYLKMKQDLGAEYVVTQMFFDNKKYFSFVDRCRAEGITIPIIPGIKP
ICLKNQLTVLPRIFRSDIPEELASELRACKDDAAAKEIGVEWGIQQAKELIEAGVPSIHF
YSLMATESVRRIAKEVY
>A0A259HY06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriia bacterium 39-39-8|TrEMBL
MKVIDHISQAKDTLVSFEVLPPLKGKTINTLYDHLDPLMEFKPSWINVTYHRSETMFKKK
TDGTFERVEVRKRPGTVGICAAIMNHYQVDAVPHIICGGFTKRETEDALIDLDFLGIDNV
LVLRGDAAKNESAFEPEKDGNHFAIDLLSQVSNMNNGIYQDEDIKSGGKTKFCMGVAGYP
EKHFEAPNLEIDLIKLKEKVDAGADYIMTQMFFDNQKFFDFVTACKNMGINVPIIPGLKP
ITNKKQLSVLPRIFHVDIPTDLSNAINKCKTDAECEQVGTEWLIQQSKELKAFGSPVLHY
YTLGKPKVIWNVVKNVF
>A0A442GNG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MTVRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMRSARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A1W9VDN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium 4572_5.1|TrEMBL
MTSNENNNGYLVGTTLERMLKAGHFAVTGELGPPQSADGNVIREKAALLKGYVDGVNLTD
NQTAIVRISSIAAGAILIQEGLEPIIQMTCRDRNRLAIQADLLGAYALGIRNLLCLTGDH
QIFGNHPTAKHVFDMDSIQLVQMVTKMRDQKVFQCGEEFKGQEPRFLVGAASAPLADPLG
FRPYRLAKKIKAGANFIQTQLVYDIEAFAKFMEKIREMGLHEKTSILVGVGPLKSPGMAR
YMKNNVPGIDVPDEIIKRMSAAGKGEPWFGKKNADMTKEEKRARSKARQAEGIQVCIDLI
KQLREIEGVAGVHIMAIEWEKAVKPIVEGAGLYPRPSV
>A0A1G9XA00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera paucivorans|TrEMBL
MNTLKEKHKDGKFTITVELDPPKSASAKITEEQASTLKGLVDGINIADCPMAKMRMSPIA
LAHIIQEDCGIETIFHLTCRDRNYIGLQAELLGAAGLGVHNILTLTGDNPQNGDTPQAKA
VFDTDTCGLIRLAHTLNTGTDINENALGAATHFYIGAAANPGISDQSLEMAKLANKVSSG
AEFIQTQPIYDLEVAKRFIDNASRFNIPILLGLMPLRGIKMATYLENNVPGISIPMSIMD
RLRKGGLEAGIEIAREQYTEIRQLSAGVHIMPMNHIDIINEIVKA
>A0A418G5X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus anginosus|TrEMBL
MSSPSPSLSFEVFPPNPAVGNEKIMATLKEMQDLVPHFISVTASNNKFNIEETTVRLADF
IRNDLHIPTIAHLPAVYLTKEMVTETLTALDKVGVHKVLALRGDILPDVEPQKDFVYATD
LIEYIKKEAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYD
FQDKCILAGIEVPIHAGIMPILNRNQVLRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSDTAHRVYQATHTFFNK
>A0A5N1G8A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus anginosus|TrEMBL
MSSPSPSLSFEVFPPNPAVGNEKIMVALKEMQDLVPHFISVTASNNKFNIEETTVRLADF
IHNDLHIPTIAHLPAVYLTKEMVTETLTALDKVGVHKVLALRGDIFPNMEPKKDFTYATD
LIEYIKEQAPHFEIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYD
FQDKCILAGIEVPIHAGIMPILNRNQVLRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSDTAHRIYQATHTFFDK
>D8F8P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|delta proteobacterium NaphS2|TrEMBL
MKTKTPSKLEKILAAGNLAVTSECGPPRGSDPEAITKKAGMIKDHVDAINITDNQTSVTR
LCSLASCIHLKLMGLEPILQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQQFGDSS
QGQNVFDIDSMQLIQTVRHMRDDGKFLGGDDINRPPRMFVGAAANPFADPFEIRTPRLAK
KIAAGVEFIQTQCIYNLDKFELWMQQNRDRGLHEKAYIMAGVTPFKSAGMAKYMKNRVPG
MDVPDDVVKRMAGVPKEKQAQEGIDICVETIQRLKECDGVSGFHVMAIEWEEKVPEIVER
SGLYPRPEAVE
>A0A0P9JBI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. atropurpurea|TrEMBL
MGSMSQDRRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVL
QLENEVKVPAAPHLSCVGDGKDDLRSLLAQYREAGIKRIVALRGDLPSGMGMASGELRHA
NDLVSFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKAKAGANSAITQYFFNADS
YFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQ
AFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A7C3GYL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiaceae bacterium|TrEMBL
MNPTFSFELFPPKTEKGMQKLQRQQVPLLQELGPEFFSVTYGAGGSTQVQTFATVDWLVS
QGIEVAPHLSCIGASREQIGGILDRYRDQGVTRLVALRGDIPSGMGDYGEFRYANELVSF
IREHSGEHFHIEVAAYPEFHPQAASAKDDERAFTIKAAAGANSAITQYFYNADAYFAFVD
DCTRLGIDIPIVPGIMPITNYQQLSRFSDACGAEIPRWIRKRLESHGDDLDAIRDFGTDV
VSTLCQRLLDGGAPGLHFYTMNQAAPTIAIWKNLDLPVPA
>A0A1H7WNZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophus gentianae|TrEMBL
MTVTWELVPGRGAREKAQESVLLEAEKAARGGKIQAVSVTDNPGGQPALMADSLACEIKA
LGIEPLVHFTCKDKNRSQIESQLYALERAGVRNLLVMSGDYPVSGFMGRPQPVFDLDPTH
VLALIRDMNSGLEYPLPKGTGRLQPGHFFAGAAVSPFKQTEAELLGQYYKLKKKIDCGAS
FVVTQLGYDIRKFQEVLLYMKRRGIEVPVLGNVYILSYPVARLMKENRLPGCVVTDGLMA
QLDRERSLPDKGVEARLLRAAKMYALLKGLGFSGAHIGGHLVTCEQVESVIEKGEELSAS
WETLIREFQYPLPGGFYFFQEDPYRKLNQSAPESRQGLSSDVSEKGLYGFSIFLHNLFFE
PGRKGFALMRLFARKLKGTRLENFLHKLEHLLKTLLYDCRDCGDCALVDVAFLCPMSQCP
KQQRNGPCGGSYQGWCEVYPGRRRCIYVRAYSRLKSRHQENLLEEIPVAPCNWDLNSSSA
WLNFFLGKDHTAKRLGISELPDKPESSGSNSRSA
>A0A1F7FK32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Raymondbacteria bacterium RIFOXYD12_FULL_49_13|TrEMBL
MNIPNHIQAQKAAGIPTISIEILPPRNGENIENIFRVLDDLKGKKLDFISVTHGAGGSLR
GGTEAISSLVRERYGIEPLLHLTCLEQSRQQIENMLMVFKYLGMTNILALRGDPPQGETQ
FIAHPYGHKLALDLMKQIAALNQGKHLIRQSDIEFMNLPKDAQYRDGEKTVFAIFGACYP
EGHPEGSGPEIQRDYTILKAEAGARAFITQLIFDEKIYTKFMDDLKARGKELVVLPGIMP
ITRKKQLPYVKKFFKSFIPEEIENAIVSAATDQEAEEKGLALCAQLCKRMLKAGAPGIHF
YSMNNGGHIRRILDLM
>A0A1G5E2L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio sp. AR14|TrEMBL
MSFEVFPPKKNDEFDNCYNVLDSLAKLNPDFISVTYGAGGSRSKKTVEIASYIQNTLKID
AMAHITCVGSSEDDILEVTKDLEASGVSHVLALRGDKPRDMSDEQFAKRIFPHATDLIRF
LNTNTNLDVSAACYPEKHPEAMSIDSDLAFMKMKQDMGAKMFISQLFFDNADFYRFVERA
DKAEIHVPIVAGIMPITSAKQIGSTVTLAGSSVPKKLADICAKYGDFPEDMRKAGIEYAI
DQIRDLRKCGMGHIHLYCMNKPKMTEIICKSI
>A0A0X4EGS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter genomosp. O|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>G9KBN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mustela putorius furo|TrEMBL
WEEEEGGFSYAADLVKHIRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADF
IITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVI
EPIKDNDDAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWIEDPR
RPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYY
LFYLKSKSPREELLKMWGEELTSEESVFEVFAHYLSGEPNQHGYKVTCLPWNDEPLAAET
SLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPNGGYVFQKAYLEFFTSRETVGA
LLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWK
DEAFALWIEQWGKLYDEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLN
RPEPEQDTQ
>A0A2V3UWL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomonas natatoria|TrEMBL
MTLSLKQLAEAREALGTPLFAGLAGDVEVSFEFFPPKTEKMEETLWDTLTTLAPLGPKFV
SVTYGAGGSTRERTHATVARIASETAIPAAAHLTCVDATRDEIDTIAQSYWDAGVRHIVA
LRGDPPRMGEKFVAHPKGYANAAELVKGLKQVAPFEISVAAYPETHPDADCADSDIDNLK
RKLDAGADQAITQFFFSPEAFFRFRDAYTRAGITAPILPGILPVSNVATTRKIAGACGTE
IPQWMNDLFEGLDDHPTTRQLVAATVAAEMCRRLYSGGVRHFHFYTLNRAELSFAICHLL
GLRAPKAAAAPVLQENAA
>A0A4Q3FCL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriaceae bacterium|TrEMBL
MKITDHIANANGKTLFSFELLPPIKGQGIQGIFDAIDPLMEFNPPFIDVTTSREDSYYKE
RDNGLLEKLTYRKRPGTVAVCAAIMNRYKVDAVPHLLCGGFTKEETEYALIDLQFLGIDN
VLVLRGDARKGDAGFVPTPGGHTYATELLEQVHNMNKGKYLHEDHEAFKTNFCTGIAAYP
EKHFEAPNLKSDFQFLKKKVNLGADFMVTQMFFDNSKYAEFVKGCQENGIDIPIIPGLKP
LTTAKQLINLPKIFHIDIPEALSDAVQSCKNDKEVKEVGIEWMINQCKELKEMGAPVLHF
YTMGNAEPTKRIAKEVF
>A0A2A3UA12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriaceae bacterium|TrEMBL
MKLTQKLSQTERTLFSIEILPPLKGKSIQSIYDGIDPLMEFNPAFVDVTYHREEYIYKKR
EGGYLEKVSIRKRPGTVGICAAIMNKYNVDAVPHIICGGFTKEETENALIDLQFLGIDNV
LALRGDSIKTEASFVPEPGGNEYALDLVKQIGEMNRGHYIDNDMTDAAPTDFCIGVAAYP
EKHFEAPNIITDLKNLKAKVDAGAEYVVTQMFFENKKYFEFVALCREHGITVPIIPGLKI
LTSKKQITALPKIFQCDIPQPFYEELEKCTDDKQIKEIGVKWCIEQSKELVKANVPCLHF
YTMGASETTKAVAKAVF
>A0A2N4U2T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp. JR1/69-3-13|TrEMBL
MSANKAISLEFFPPRDTAAQEKLVRSAKQLLALEPAYVSVTFGAGGSTRSGTADTVRLLQ
NLGCDAAPHLSCIGATRAVLGEILDAYREQGVRRIVALRGDMPSGMGGDQGELHYASELV
AFIRQHSGDWFHIEVAGYPEMHPQSASAEADLAHFIHKVQAGADSAITQYFFNADAYFDF
VERISAKGVDIPVVPGIMPITNYTQLARFSTMCGAEIPRWIRLRLADFGDDKASIKAFGI
DVISRLSQDLLDNGAPGLHFYTLNNAEVTMAIWRQLRLD
>A0A167YBY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cordyceps fumosorosea (strain ARSEF 2679)|TrEMBL
MEKITDKIAALPPDGEYFSLEFFPPKTAMGFSNLRDRLNRMEQGLRPLFVNVTWGAGGST
ADKSLELAELCQRELGMTTCLHLTCTNMSRKLIDKALDDAKALGIRNILALRGDPPRKDE
YRTDDDDESDAEAGEDFVWAIDLVKYIRRKHGDYFCVGVAAYPEGHADESHPLGQSLEHD
LPYLVDKVQAGADFIMTQLFFDIDAYEKFEATLRQHPSGAFKTIPIMPGLMPIQSYAMIK
RTAKLSHAAMPPAILDRLNAVKGDDERVKAVGVDILAELVEQVRTVKAKTPGPKGFHFYT
LNLEKAVTFILERTNLIPDSPALEEAVVDGPLPASAAPPSLQVNGHAIPPPRSHSRSSRR
HSSVGSDPHNRVIVDNGGRRAPNPAWEATGAEAAVPAEALNARANTLAISEGEGALGREA
TWDDFPNGRFGDARSPAYGEIDGYGVSLHVSVAQAVRLWGRPATTADLDDMFVRHVRGQL
AALPWSVEEELLPESSAITPHLAALNARGWWTVASQPAVDGARSADETFGWGPADGFVFQ
KAFVEFFLPAADWAALRDRLRRDGTHEVVCFYASNAKGDFVCSDGATGGSSSTNAVTWGV
FPGKEIVTPTIIEEVSFRAWCEEAFSIWDEWSRVYPRGSPSAALLGGVRDDYWLVNVIHH
DFVDQQALWDLLLA
>A0A1C5YSS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MKIIDRLKEDKIHISFEVFPPKTDAGFEKVIAATDAMAKLNPAFISVTYGAGGGTSKNTA
KIASHIKDDLGVVSLAHLTCASSTIEEVRDVIENLKENGIENILALRGDIPEGMPFPNGN
RFRYAYELIEEIRKHGDFCIGAACYPEGHVENEHKAEDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGINVPVLPGIMPMTSEKQMKRSQELSGTVFPRRFLALLDRFGSSAA
AMEQAGIAYATDQIIDLLSNGVNNIHIYTMNKPHVAAAIMNNLSEIIKA
>A0A1H8XCV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. NFIX58|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKGVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A849RBR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSKEPRRLSEVLSSGQFAVTIEYNPPKGTNISKVLESAKELVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGRDMAG
>C5NUG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemella haemolysans ATCC 10379|TrEMBL
MRNLLERLEQNVLVADGAMGTALYSNGLESCHEYNNISNPDSVEKIHKAYIEAGADIIQT
NTYAAKKCQLKTYGYEDKFEEINIRAAEIARKAAGENTFVFGTIGAIRGLRECELSLETI
VNETIDQVKVLLSTNKVDALLFETYYDQEEIRAVLTEARKLTDLPIITNISLLEAGITQN
GEKVTDALSTLVNLGADIVGLNCHLGPYHMIKSLKQVPLFAQSYLSAYPNASLLQLTQTI
NGNEYRFRKNSAYFEQSAKLLVEEGVRLIGGCCGTTPEHIRAIKKGIKDLKPVKRKIITP
LPAEEELVRVAHNEPTIVDKVKKQVTIIAELDPPKHLNVDKFIEGAKAIDKKNIEAITLA
DNSLASTRICNLAAATLLKEHISTPTLLHLTCRDHNLIGLQSRLMGFDLLGINNVLALTG
DPSKLGDFPGATSVYDMTSLKLIPFIKQLNEGLGYNGASLKKTTNFTVAAAYNPNVRDLS
KTKRLVEKKIKAGTDYFITQPVFEAEKIEQLAEFAADYPDTPFFVGIMPITSYNNAVFLH
NEVPGIKLSEEFLAKLEEVKDDKELCQKIALEESKKLLDVALKHFKGIYLITPFFRYDLT
LELIDYVEENKDK
>A0A220U243|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Virgibacillus phasianinus|TrEMBL
MGLLDDLNEKILIGDGAMGTLLYANGINSCFEELNLSHPQQVLAIHQSYLDAGATVIQTN
TYGANYPKLAGYGLQDHVKEINSKAVRLAKEAAQENAYVLGTIGGIRGIKKGEETIEELK
RSFREQLYCLLLEGVDGILFETYYDLEELTTMLAIARKETDLPLIAQVSLHEPGTLQNGT
PLADALIHLETIGADVVGLNCRLGPYHMIRSLEQVDIPQNAFLSAYPNAGLPEYVDGKLT
YQSDPKYFEESALSFRAEGVRLIGGCCGTTPRHIEAMAKKLAGLKPVTRKTVKKREASIS
VTGSRKENQSGLHELARDRRSIIVELDPPKKLNIEEFFKGAKALEQAGIDALTLADNSLA
TPRVSNLSIASMLKNQLNQRSLVHVACRDRNLIGLQSHLMGLHALGIHDVLAITGDPTKV
GNFPGATSVYDCNSFDLIQLCKQFNEGISYSGKSLGEKTNFSIAGAFNPNVHHLDKAVRR
LEKKIHAGADYFLTQPIFSEQQMIEVYHATKQLNVPIYIGIMPLTSSQNAEFLHNEVPGI
KLSQTIRERLALFADNRPEAVREGIAIAKSLLDAAMDLFNGIYLITPFMRYDMTVELVEY
INAKKSSVRSLNLIEK
>A0A833LV96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dechloromonas sp|TrEMBL
MNTNISIEFFPPQTPEGVEKLRATRAELAKLKPEFFSVTYGAGGSTRERTFAIVREIASE
GFDAAPHLSCIGSTRESIREILAEFKAAGIRRIVALRGDLPSGMAEAGEFRYANELVEFI
RAETGSHFSIEVAAYPEWHPQARSPKDDLDAFARKVKAGANSAITQYFYNADAYFHFVDE
ARALGVDIPIVPGIMPIVGFTKLARFSDACGADLPRWMRKKFESFGDDSESIRTFGLDLV
TELCERLLKGGAPGLHFYSMNQSALTTEICRRLG
>A0A1D1VQM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramazzottius varieornatus|TrEMBL
MVISKMDSVDTNGHHSPDAYDGSACHQNGVSKQASLRQSSSNGSSAYVPLIEKINQHIES
GTKFFSFEYLPPRTPNSAPNLLARIERMTAGGPLFIDITWHLAGDPMGDKETSSMMVANA
AVNYVGVETMLHITCQKYSKEEIRQALHRAKDMGLRNILALRGDIPVNQVSSETPKDGLS
NAEEMVKLVREDFGDHFCVCVAGYTQGHPDAVSYEQDLVYLKQKVDAGANFIITQLFFEA
QHYIKFVKDCRAIGITVPIIPGIFPIQSYNSLQNVTKLSKLTIPQSIISAITPIKDNDQA
IRHLGIGLATAMCKELLDAGAPSLHFYTMNLEVATIEILKRLGMWLQEPKKCLPWKTSAN
YKRQAEDVRPIFWQNRPNSYIQRTIEWDEFPNGRWGNSASPAFGQLDYNLFYLQGRIPKE
QLLNMWGRELTCVQDVFDVFCDYISGREREDGSKVVSLPWSDGELSPETLPLLDQLLRLN
KNGILTINSQPSVNGAPSTDKVHGWGNPGGYVYQKAYVEFFISEDRLPTLLSELKDYPKV
TFHIINQAGEEFSDGGQDANAVTWGVFPGREIIQPTVVDPESFRYWKDEAFALWQEQWGS
LYPAVSPSRKIIDSVRTNFYLVNLVDNEFPKETCLWQLLNGVLKA
>A0A1C6F2T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENILALRGDMVEGVEPQKD
FTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIRNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A532CBN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPRRLREILDQGQFAVTIEYNPPKGTNISGVLENAKQLVGRVHGVNVTDNTAAVVRA
GSLSVCRLLYELGHDPVMQMTCRDRNRIGIQSDLMGASMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGKDMAGNKLDGSTVFTIGAAVTPEADPLGPMLAKFEVKV
KAGAQFFQTQAIYHPEQFASFMKAVRPFKAKVLAGILVLRNAKMAEFMNANIPGVSVPQD
MIDELRAAGPERAEDVGVDIAVRTIKAVRSHCDGVHIMAIKATHRLAEIITKAEVG
>K5UY99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. HENC-03|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDASRDELINIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A3S2VF56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. RMa-01|TrEMBL
MMIAPQSESREKAPLADLLSHYSIEVTSRDLPSLQSMTATLPPGSEVFVAHLPKEDIGLL
VRAAAGLRDAGFVPVPHIVARNIRNRLELDTMLARLSEEAGVRHALVLGGDRDDAAGTFG
SALDLIETGLFQTYGIGRIAIACYPEGHPRIAGAVLDTALTAKVDAAARAGLDVLLVSQF
LFDQKPLLSFARRLRERGVTVPLRVGIAGPASRTKLLKYALRCGVGASLRALRERSEVAR
NVLSGETPEELLIDIAAAEAAEPDLGISGVHFFTFGDPAQSIRWAEQQAASD
>A0A208Y0J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pigmentiphaga sp. NML080357|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A7U4E2V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella baltica OS117|TrEMBL
MAFHHAQHSQSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPGWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A7U8ZNJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia albertii|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKEVADFDISVAAYPEVHQEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A7G6DU06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia muciniphila|TrEMBL
MHLRERLQSGAGPSLSFEFFPPKNEQAASALYQTIRELEPYRPSFVSVTYGAGGSTRELT
REVVLRIQHESRIPTVPHLTCVGHSRKEVWNILDQYARAGVRAVLALRGDPPRGAKDYNR
DADVFRHAADLVTFIREYNESGRHPDPDGFAIGVAGFPEGHPATPNRLREMDFLKAKVDA
GADYICTQLFFDNHSFLDYRERCLLAGIKVPILAGIMPVTSLSGMNRMAELSGGTCFPAR
LLKALKRAGSNPDAIQEVGIQYASSQCAELLDSDVDGIHFYTLNQSRATREIYRNLGLKD
SLQLLEHGEDK
>A0A7U8KMZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter radioresistens SH164|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKLVHQDLQYLNPEFFSVTYGAGGSTRERTLAAIEEFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQNIKRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIRRFIEKVNAGANAGITQFFFNPDSYFYFL
DRLAKEGIHIPIAPGIMPIINASNLIRFADGTGAEIPRWIRKQLSAYGDDSVAIKDFGHE
VVLKLCERLIAGGAPSLHFYSMNQTEPTRQLVLDLGLA
>B1JTJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cenocepacia (strain MC0-3)|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNLATATRTICERLAV
>A0A4R6RAC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquabacterium commune|TrEMBL
MTTQHRLPISLEFFPPKTPEGADKLAAVRQQLYPLQPEYCSVTYGAGGSTQDGTIQTVRA
ILAEGFDAAPHFSCIGASKASVREQLAQFQADGVKRIVALRGDLPSGYGGFGEFKYASEL
VAFIREETGSHFHIEVGAYPEMHPQARNPQADLQAYVTKVKAGADVAITQYFFNSDAYFR
FVDEAEKAGATIPVVPGIMPITNASQLIRFSDACGAEVPRWIRTRLEGFGDDKASIQAFG
LDVVTDLCDQLRCAGVPGLHFYTMNQATTVKAICERLGW
>A0A0U1LUF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces islandicus|TrEMBL
MHVGQKLQDQATSGQTGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRS
QLTCEMVRIAQTVFGLETVMHLTCTDMPRESVDEALEAAYNAGCTNILALRGDPPREKET
WEAAEGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
IVTQMFYDVDKFLDWVQKCRAKGIHAPIVPGIMPISTYDAFMRRSKWTKIHIPPVWLEKL
EPVKNDDAKVREIGTKLVSEMCRKLLDSGHIHHLHFYTMNLAQASRMILEELSLCPSNEA
PLQKPLPWRKSLGLRRRSEDVRPIFWRNRHASYITRTADWDEYPNGRWTDARSPAFGELN
AYGVRLKGTNEQNIKLFGRPKSIKELSEIFIRYLNGKLERLPWSDSPITSEADSIKQDLV
DLNQRGFITVNSQPAVNGVKSSHPIHGWGPRNGYVYQKAYLELFVPPYLVEELLARIEKN
NDLTYYCVNKSGELRTRTDEGPNAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQLGDDW
AKCHPAESPSRKLIQQVMDEWYLVNIVNNDFHKTHDLFQLFDGLVIKDLDTEISGIDPEV
DGPTQPAPASKPANS
>A0A368Y5C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodoferax soli|TrEMBL
MNTGTQPATPVSYEFFPPKTPEGAAKLRGVREALYARKPSFCSVTYGAGGSTQQGTFGTV
GEILAEGVDAASHFSCIGATKETVRTQLAELRAMGVKRLVALRGDLPSGYGAGGEFQYAS
DLVAFIRAETGDAFHIEVAAYPEVHPQARSPEADLQAYAAKVRAGADSAITQYFYNADAY
FRFCADSQRLGLDVPIVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIKS
FGLDVVAALCEQLLRGGAPGLHFYTMNQSVATLELCRRLGL
>A0A0V1BFB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella spiralis|TrEMBL
MNSSYNLQMKLKSPAYQRAVTDFGVYFEEDSFLSLMASLEAVELKATGHDLNSAAKKSTD
EIYRSLIDRIKENISSGRRFFSLEFFPPHTTEGLINLLKRVDIFANSQPLFVDVTWVMRS
DPASEKVTSSSSLADCILNFCLLDTMLHITSVQYNEKTVLFNLERAKKIGIRNILALRGD
ISDDANVTTTDFQYACQLVRFIRSHYGDYFTICVAEDLLNLKAKVDAGADFIITQLFFDE
MHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSKIVIPDSVLTTLESIKENAEA
VRNFGISFAVQLCRKLLNREHHVVPGLHFYTLNQEKSTRQKNYFILINYLYWIYKKYLQQ
IGFWKKAPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYLCRTRDWKQFPHSRWGDVGN
PAFGNLKHYLFSCIDQMDDSCALDMWDKELSTLEHVRDIFCNFIARTPNRHGHSVRRLPW
NENHLDPAADILKNELIYYNSNGILTINCQAAVNGLPSSDPIFGWGEANGYIYQKGYLEF
FASSTCTTILLNHVQNFPSINYHAINFDGSFETFNYDEDATVALTWGVFVGQEIVQPTVA
NAASFRVWKDEAFDLWQRWAGLYESGSIGRKLLQKIHDDYRLITLIDNDYPQPCSLSALL
RAVISDYWGKKLDDG
>A0A451DEV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MIYIIKDSNKPHNYESYHLKNKIRVSFEVFPPQNSKLEEKLLRSICVLNQFHPDFFSVTN
SIHAKNRDKTFFVVQKIRALTKVNVFAHFTTIGLNKSEIQNIACKYWDCGIKHIIALRGD
LPDQYSQKIIYANDLIKLLQSIHDFEILVAAYPELHPESCNIQEDLINLKNKADLGVKKA
ITQFFFSIEKFLRFRDNCINIGLPITIIPGILPILNINQLRKFSCLTNVYIPKWIFSAFD
EYKNDVNKCMDLSVRIAVNLIVSLYNEGITNFHLYTLNQSTLSFKICHQLGLI
>A0A0J7IWP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium koreense CCUG 49689|TrEMBL
MKITEHIKNANGKTLFSIEVIPPTKGTGIEDLYKNIDPLMEFKPPFIDVTTSREEYVYIE
KGNGLVERKITRMRPGTLGICASIQHKYDVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGQNHYVPTEGGHEYAIHLVEHINDIGRGKYLTDEKRCDHENKFCIGVAGY
PEKHIEAPSMKYDLQRLKEKVEAGADYVVTQMFFDNKKYFEFVKEARKIGIDVPIIPGIK
PIATKGHLSMLPKTFKIDLPEELISEIAKAKDNAAIKQIGVEWAINQCRELLEFGVPVLH
FYSMGKSDNIRKVASEIF
>A0A3M6QVJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Franklinella schreckenbergeri|TrEMBL
MPAPTPALPLSLEFFPPKTEAGALKLRQARQQLYALAPQFCSVTYGAGGSTQAGTFATVG
EILAEGQDAASHFSCIGAHAAKLRAELQELRDMGVKRLVALRGDLPSGYGISSRQAEQRF
QYASDLVAFVREETGAHFHIEVAAYPEMHPQAASPQKDLQAFAAKVRAGADSAITQYFFN
ADAYFRFVDEARALGVDVPIVPGIMPIMGASQLLRFSDACGAEVPRWIRTRLQALGDDVD
GIRAFGLDAVTALCERLITGGAPGLHFYTMNQSPLVLEVARRLGLHPAAPDAPAA
>A0A1S1V996|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Andreesenia angusta|TrEMBL
MNIREYLKENTLLADGAMGTYYSELTGDKISFCEFASLEKPEVISRIHREYIEAGAKLIR
TNTFSANTVTLEASRETVGRIIDEAYSIAKEAVEGKEVFIGCSIGPIHESRMGVEAVDVL
EEYRYVADRFLKNGAEVFVFETFGTLEYLEEITSYIKGKNPEVFILTQFAVTMDGFTRKG
ISIKNLVEAVKQIDGIDMYGFNCGSGPAHLYKVLKNADVFEDPISVLPNASYPEIENGRM
VYVNNPDYFADIVYNISELGAKIVGGCCGTTPEHIRSINRKLQSGLPQAEKPETSAKIVE
VSEKKSVNSFKEKLEQGKFVLAVELDPPFDTDIEKLMESARVCKLEGIDLVTVADSPRAI
ARVDSMMVASKIMREVGIETIPHLCCRDKNLNAIKSGVLGAHIDGIRNILAITGDPILDI
DKLSTKSVFNLNSYELINLISEMNHEIFKQDSMLISGALNLNVKNKDAQMGRLKRKVEKG
AEIFFTQPIFEESVIEYIENMEREPNVKIMAGIMPIVSYKNALFLNNEVPGIHIPDKYVD
MFRETVDKAESEAIGIDIAVDMVRRIRDKVDGLYFITPFGRIEIIQSILEKIR
>C2NMV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus BGSC 6E1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEALKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A842PKD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomicrobia archaeon|TrEMBL
MGEKMGDEVYSDLMRELKEGKYVFTGELEPEKAGDVNEPIEMARELVGLVVACNVTDNPQ
SFAYVNSMAASYLIQKETGMECVYQLRCSDRNRMALLSDVLGAGALGLKNILALAGDHVS
LGDTPDAKPVFDLDSTTLIAMIRKMVDEGKDLGGNEIHNPPKLHVGGAAAPGAAHLKAEV
AKVKRKINVGVEYLQTQVVYYTDVLDKFFNELGKVDVPILVGIFPARTFGQANFFHENVA
GVDVPPDYLEAMRKTKEIKDKEKRKEEVDRVNIEFFTGFLEHLKGTPAAGCHMMAVGYPR
IIAPLKKVME
>B3T169|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured marine microorganism HF4000_008G09|TrEMBL
MNFSLEIGLKTDLSNLPKVKNVYITLLPGEDFRQVANKAKELTNLGFNPVPHFSARSIKN
LNDLKDYVKRCKDGGVKQALVIGGSAQPIGDFHSSLQLLKTGLFEGFRIGIAGHPDGSPD
ISDSDLEKAMSDKKPYADYIVTQWLMEPEPIIKFVSKQTIPVHVGITGPMKISSLLKFAN
TVGAKNSINFIKSNLGKTFDLLRPKDPNDLIEKVKSVTNNFHIYTFGGLKETSAWLMKKK
YA
>A0A7X0J6B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter cryoconitis|TrEMBL
MKITDHITNAKGKTLFSFELLPPVKGKSITDIYNAIDPLMEFNPPFIDVTYHREDYIYKQ
HDNGLLEKVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADSTFIPTPGGHAYATDLLGQVSDMNQGRYLFEDHSAFQTDFCIGVAGYP
EKHFEAPNLKTDFKYLKQKVEMGAEFIVTQMFFDNAKYCDFVAQCRANGINVPIIPGLKP
ITSSKQLISLPKIFHIDLPEDLTEAIQECKTEKDVKEVGIEWMIQQCKELIKVGAPVLHF
YTMSNPEPTKRIARAVF
>A0A3D9U8T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus cabanillasii|TrEMBL
MSFFHANHQEALNQNLAELEGQIRVSFEFFPPRTTEMEQTLWKSIDRLSKLKPNFVSVTY
GANSGERNRTHSIIKGIKDKTGLDAAPHLTCIDASREELRDIARDYWKNGIRHIVALRGD
LPDGSCKPEMYGTDLVELLKSEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFAAITNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>U7Q2L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183)|TrEMBL
MDKITDKIAALSPESYYFSLEFFPPKTSMGFANLRGRLDRMARALRPLFVNVTWGAGGST
AQKSLELAEICQRELGLTTCLHLTCTNMSRELIDKALEDAKALGIRNILALRGDPPRPTE
YSDETDKDAAAAGIAPGPSGELEFSWAVDLVRYIRKQHGDYFCIGVAAYPEGHAEESHPL
GQSLEHDLPYLVEKVQAGADFVMTQLFFDHAAYAHFESVLLAHPSGAFKDIPLIPGLMPI
QNYQMIKRTTKLSHARIPDELMARLDAVKKDDEKVKSVGVDIISELVEQVKEIKDRTRAD
RPKGFHFYTLNLEKAVSFILERTHLIPPGTPDEDEEAIAGEVAVVDDVATSGSLGVPSIR
INGSTGTGTGGAVHPPLDGHPARRQSSIGSDPRNRVIVSGRAASHPDYEATALEASVPAE
PVNTRSNTLAISEGEGVLGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMTVNQALKL
WGRPTTTEDINTIFIRYLGGELAAIPWSEEEFNAETATIRDQLVQLNAKGWWTVASQPAV
NGIPSTDATFGWGPTHGFVFQKAFVEFFLPSADWTALCTRLTDPEVRDKVCFYAINAAGD
FVSSDASGRVTDSRSGAEAAEEASTNAVTWGVFPGKEIVTPTIVEEVSFRAWSEEAFGIW
KEWAALYPKGSPTDILLEKTRNDYWLVNIIHHNYIEKDALWNLVSA
>A0A1X2ID59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Absidia repens|TrEMBL
MKLVDKFAKAQNDRSLSYSFEYFPPKTELGLANLLDRVTRMSKWEPTFISCTWGAGGSSQ
ERTMAVCSTGQVVNGVETLLHLTCTNMEKESLDEALLKAKDAGIQNILALRGDAPRGHEY
WTPIENGFTHAVDLVRYIRQQYGDYFCIGVAGYPEGHMDAESKEDDLLHLKEKIDAGADF
ILTQLFYNVDTFVNWVATCRSNGITVPIVPGIMPIPTYQNFRRMINLCKTQVPEDILQRL
DTIKADDQKVKDYGVSLAVQMIKQLHEKHGICNFHLSTLNLERSTKLILQQLNLISQDTI
KKQPSYSKLLASYSTPQDLEHAENWDEFQMAVMVIQDLQVTYGASQSLPTSEASRKWGYP
KTVEDITGIFERYILGQLDSLPWSEDRLQTETDAIRQALTEINRRGYWSVGSQPSVNGVP
SQDPVFGWGPKGGYVYQKAFLEFFVSPKQLEQILKRFDQDPVVTYYAMNRNGDLRTNVLD
QEAQNAVTWGVFPGKEIVQPTLIERANFESWNEEAFGLWTTWEQQYAPDSDTAKLLKQVG
DSFWLVNVVHNDYQQVDGLFNMMLA
>A0A251ZA07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. Lanier|TrEMBL
MAPGFEQALAGPRPVITAEITPPLGGDPSRALAAAESLRGLVQAFNVTDGSRAVMRMGSL
ALCKLLQERGLEPVLQLGCRDRNRIGLQAELLGAHALGLRNVLCLTGDPVRAGNQPLARP
VFDLESVRLLLQVQALNQGLDPLGKVLPDGPTSLFAGAAADPQSPSWSGLKSRTARKAAA
GARFLQTQMVMDPEALRRFCGEITNPLGLPVLAGVFLLKSAKNASFINRVVPGAQIPQAL
IDRLAAAADPRVEGIRIAAEQVSSYCKIAAGVHLMAIKAEESLVDVLALAEI
>A0A4V6QF99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides salmoniphilum|TrEMBL
MTTHPLDRDATVAELRDPGSIADRLAAVQPGDVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDLE
RDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELASSTLPAALEERLLQAAGGGPEENRDEVRKVGVEVTTAMASRLIAEGVPCVHFM
TLNFARATSEVLENLGLRVTPGTGRA
>A0A1A9BMG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DI166|TrEMBL
MREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSVTYGAGGTTRAGTVKA
TEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALRGDPPGDPMGEWVPHP
RGLTYAAELVELIKNSGDFCVGVAAFPAMHPRSAEWESDVRHFVDKCRAGADYAITQMFF
QPEDYLRLRDRVDAAGCATPIIPEIMPIASVRTLERIPSLTNAAFPAALKERILTAKDDP
AAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPRV
>A0A366M511|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spongiactinospora rosea|TrEMBL
MSLGRPSVRPGRVPTVRELLASGDRSFSFEFFPPKSEEGERQLWRAIRELEALSPTFVSV
TYGAGGGNRDRTVGIVERVAHETTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVR
GDPPGDPMGEWVQHPEGVLYAEELVRLIRQSGDFCVGVAAFPYKHPRSATIESDTDFFVR
KCRAGADYAITQMFFRADDYLRLRDRVAAGGCDTPIIPGIMPVTRMSTIARSEQLSGAPF
PEEVAARFEEVKDDPEAVRELGIEHAAELCRRLLDEGAPGIHFITFNRSSATREVFQRIA
PVPAASPV
>A0A5D4GF31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis bv. diacetylactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPNIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTF
>A0A366AMX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio paracholerae|TrEMBL
MGYTHAGHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQNIVALRGDI
PAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDVESYLRFRDRCVAAGIEVEIVPGILPVSNFKQASRFAAQNNVKVPNWMVKQFEG
LEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A317MCZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sp. S165|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIDSIYDHLDPLMEFKPAFINVTYHRSEHMFKKR
ADGTFEKVEIRKRPGTVAICAALMNHYNVDAVPHLICGGFSREETENALIDLNFLGVDNV
LVLRGDAPKNETFFEPEPHGHRYADELLQQVTHMNNGIYLEEDLQGGVKTNFCIGVAGYP
EKHFEAPNMQTDMTYLKKKVENGADYIVTQMFFDNQKFFDFVNKCREAGITVPIIPGLKP
ITSRKQLTVLPRTFHVDIPAEFANEILKCKTDKEVEEVGTAWLIQQSKELKAFGVPVLHY
YTLGKPHVIRKAVEAVV
>A0A1E3LSF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas turrisvirgatae|TrEMBL
MSIVLDPQAPLFADVAGDIDVSFEFFPPKTEKMEATLWESIQTLSPLGPRFVSVTYGAGG
TTRERTHNTVARIARETPIAAAAHLTCVEATREEIDAVANEYWAAGVRHIVALRGDPPTA
GTKFQSPVGGYQNAAALVAGLRRLHPFEISVAAYPECHPDSPDAAHDLDNLKRKIDAGAN
RAITQFFFEPDTFFRFRDKAAKAGIDAEIVPGIMPVMSFAAVQKMSAMCGTDVPAWMARL
FEGLDDRPAARQLVAATLAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGVRPTGAA
RVVAA
>V9L019|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callorhinchus milii|TrEMBL
PGIFPIQGYHSLRQLVKLSKLQVPQEIKDIIEPIKDNDAAIRNCGIDLATDLCKALLTSG
AVPGLHFYTLNREVAATEILRRLGLWIEDPRRPLPWAVSANPKRKVEDVRPIFWASRPKS
YIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSNCAKEELLKMWGEELVNEEHVFE
VFTAYITGESNRNGTKVTCLPWNDESLAVETNLMKAELQKVNRRGILTINSQPNINAKSS
TDPVVGWGPEGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVKSENINNASD
LQPNAVTWGIFPGREIIQPTVVDPISFMYWKDEAFALWIERWAKLYPEESPSRQIIQNIH
DNYYLVNLVDNDFPLKNCLWQVIEDMFLLKSIEKPCDDAAAADDLAAVP
>R5Z2E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium CAG:25|TrEMBL
MKISEILKNKSTISFEVFPPKNKEGNISSIYSTIEGLAKLSPDFISVTYGAGGSTKGKTV
EIASVIKHEYGIESVAHLSCISSTKEDIKYECERLKEAGIDNILALRGDYPADATNFDPE
NLEFHYASELNEFIGEHFKGQFCLSGACYPETHQEADGFKKDLEALKKKVDAGAEYLVTQ
IFFDNDYYYRLVREARKIGITVPILAGIMPITNAKSLIRTTKMCGCTIPYQLSTMIEAHY
DNPEAMKEIGINYAAQQIIDLITNGVDGIHIYTMNRAETAQRVFDSIPAVLKELN
>A0A6A6PUS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neohortaea acidophila|TrEMBL
MAKITDKIAALPPDSNYFSLEFFPPKTQQGFSNLHARLSRMAQALRPLFVNVTWGAGGST
STKSLALAELTQRSLGLTTCLHLTCTNMSRRLIDEALEQAKALGVRNILALRGDPPRSEE
YRDDSQAAAEEDDSNKDFTWAVDLVRYIRRQYGDYFCVGVAGYPEGHSDQSHPEHQSVEH
DLPYLVEKTAAGADFIMTQLFYDVDAYQQYERTLREHESGVFKTIPIIPGLMPIQSYQIL
CRTTKLSHASLPADISSRLHAVKGDDEAVKRVGVDILSEMIGKMEKLPSPGPRGFHFYTL
NLEKVVSQILERCDLIPSTPPIILAPPENGAQVEEAIVEEESEGYMVVTDLKKRRQSSLA
NSQPRNRVVVSRDRASSASSTRTSALEAPEDQAGVPKDRINSRANTLAISEGQGDLGREA
TWDDFPNGRWGDARSPAYGEIDGYGVSLHVSAPNAKRLWGEPSKIADISALFQQHLEGEI
DAMPWSEEALQPETLIIKPKLLSMINKGWWTIASQPAVKGVRSTDPIFGWGPKNGFVFQK
PFVEFFVPSADWKRLQQALGEDEQITYFAGNWAGDFVCSDEESVNPVTWGTFTGKEIITP
TIIEAVSFKAWLEEAFGIWGEWQRVYEPGSKSSKLLEKVRKDYWLVNVIDHGFVVPGALW
KVLLNEAA
>A0A8I1MUA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomonas arsenitoxydans (strain DSM 22701 / CIP 110005 / 3As)|TrEMBL
MRMASAQSVSPRVNLSFEFFPPKTAEGADKLRAVRQRLYARQPEFCSVTFGAGGSTQEGT
LQTVRDILAEGVDAAPHLSCIGASRDSVRGHLHDFQAAGVKRLVALRGDLPSGYGIGGEF
HHARDLVAFIRDEMGSAFHIEVAAYPEMHPQARSPLDDLQHFADKVRAGANSAITQYFYS
AAAYRRFVDDVRALGLDVPVVPGIMPITNSSQLLRFSEVCGAEIPRWVRLRLQSYGDDRE
SIRAFGREVVSSLCEELIASGAPGLHFYTLNQAEATLAVLDDLGR
>A0A4Q9WCI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus lugdunensis|TrEMBL
MSQFLNQLQNNILVADGAIGTILYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKPFGLEHKVKEIHKAAVKIAKRAATKNTFILGTVGGFRGIKQDDISLSTI
QYHTENQIDTLIEEGVNALLFETYYDLDELKRIVTWTKRNYDIPVVAQLTASNTTYLVDG
TEINDALAQLVTCGADVVGLNCHHGPHHMEKSFSHIALPDNAYLSCYPNASLLDIENSEF
KYSDNAQYFGAVAEKLIEQGVRLIGGCCGTTPQHIHYIKSSVSHLSPVNHKKVIPIHKKS
NQRRTDSIKQSLTSKVKQGPTVIVELDTPKHLDTDLFFENIGKLDAAHIDAVTLADNSLA
TVRISNIAAASLIKQRYDIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGSTNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKIASGMSYFITQPVYSKEKIIQVYEATKHLNIPIFIGIMPIASYNNALFLHNEVPGI
KMSESVLNQFKAVKDDKEKTKELSLRLSKDLIDTVHQYFNGLYIITPFQRVDYSLELAAY
SRSITTNKEAIL
>A0A1C7HTV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium I46|TrEMBL
MIENYLNTQGYMLFDGAFGTYYAQRYAEDQKPCEMANLNHPKRVAAIHQEYIEAGADAIK
TNTFSANEQHLECSWEMIRRILQEGYRIAKEAAKDKVKVFADIGPIMEQKNVSLAQQYQR
IADVFLAEGADCFLFETLLNTQELHAVTSYIKEQCPQACIIVSFAVTADGYSRQGIAMSR
LLQDCLADEHVDACGLNCVCGPMHMKRLLDSIDRTQKPILIMPNAGYPTILANRTYFRDS
STYFAKEMREIWQKGARLLGGCCGTTPIYIQKTREALQEHKIIQKVQQPAQETERIPQED
HNPLRRKLQKKQPVIAVEFDPPANCEIERFMNHVEFLKEAGVDAVTIADCPIARARVDSS
LIACKLHRELGLDVIPHMTCRDRNINATKALLFGLQIEGIRNVLVVTGDPIPSEDRQEVK
GVFNFNSQILAGYIRDLNETMFTSPFMVFGALNLNAVNFEAELAKAKRKVTQGMEGFLTQ
PVHSRQALFNLKRARKELQAYILGGVLPIVSHRNAVYMNNEISGIEVDEEIVAMYEGTTR
KEAQKLAVDISCKTMDEMRPYIDGYYLITPFNRVEIIADMITYIHKQ
>A0A6H2H2P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus albicereus|TrEMBL
MSSTLREKLLRKESGILTYGMTPPKSSHPPEKIREIADKQIERLKGSGIDGLVLYDVQDE
AERTDESRPFPFLQALDPTEYYEGYLKQELGVPAIIYHCVACEGPDKLASWILRDRDEQR
YSVFVGASSSRQQVQIRLPEAYRMCGILNERLLPGGVVIPERHRSKGDEHERARAKQEAG
CGFFVSQATFDVEASKSFLSDYYYSSRESGTEMAPILFNLAPCGSAKTLEFMKWLGISIP
KWLENELIHSVDILDKSVQLSRQVFRELYRFGLEKGIPIGCSVESVSTRKVEIEASIQLL
RDIREDMAQIGAELAPAVVPAP
>A0A1H7LLT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio ruminis|TrEMBL
MFKDMFANDSSLSFEVFPPKKDDEFENCYKVLDSLSELKPDFISVTYGAGGSRSKKTVEI
ASYIQNELHTDAMAHMTCVGSTSEDILAVTRDLEAVGVNHVLALRGDKPRDMSDEQFNQR
VFPHATDLIRFLNENTKLDISASCYPEKHPEAMSMDSDLAFMKMKQDMGAKMFISQLFFD
NADFYRFTERADKAGITIPIVAGIMPITSTKQIGSTVTLAGSSVPKKLADICARYGESPD
DMRKAGIEYAIDQIRDLRKCGVGHIHIYCMNKPKMTAEICKSI
>A0A1Q9VNH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. CNJ-954|TrEMBL
MVNETHRPAPASLQVAVADTLKWGTPGRVPFSVEFMPPRNDAAEQRLWSAAEAFHDLGAS
FVSVTYGAGGSSRERTERVASRLAVKPLTTLLHLTLVDHREEELRDILREFASLGLTNLL
ALRGDPPGDPMGDWTPVDGGLNFAHELIELVRSIPECADFDIGIASFPEGHYRAGSLEDD
TRYTLQKLRAGASYSITQMFFDVDHYLRLRDRLAAADPVHGAKPIIPGLMPITSLKSVRR
QLELSGASLPKELDDLLTRAAAGDEVKNAAGIREAGIEVTSRMAERLIAEGAPDLHFMTM
NNVRATQEVLHNLGMAPAWGPELGQDMVR
>A0A660REC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga sp|TrEMBL
MGRLKEDIENKRAFIVEVLTPRGTDISKTIELAMNLKRIGINVVSITDTPLGRARMSPWA
VSHNLVEMGLDVLMHFTRISRNLLRIHADLLGIHALGIRNLLVLSGDDPREGDYPESTVL
NDITTEDLIRLIRSMNLGYDLKGRRIKPNTDFLIGAVFNPFIEREIDRAKKKLENGADFL
ISQPVFKLDDLPEFHLDSSKIVISLVLFRNKKHFRLFAGVPGVRMKDGFIENMEKLDDDG
VRMRSIESASEIVRKLRNEFAGFYIIGVTTSSWKMV
>A0A5A7VUR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tardiphaga sp. P9-11|TrEMBL
MTEINPATSAKLPNISFEFFPPKTEEMDRTLWETIERLAPLNPSFVSVTYGAGGSTRERT
HATIVRLLKETHLTPAAHLTCVGAPKSEIDDVVARYHEAGVRHIVALRGDPTTGIGTQYL
AHPDGYQTSADLVASIRNRYPDIDVTVSAYPEKHPESIDFDADVDTLQAKVDAGATRAIT
QVFFDNDLYFRYIDKVRARGITIPVLPGIMPMHNFKQARNFVTRAGTTVPSWLADKFDGL
DDDAETRKLVAATVAAGQVQKLAKHGVSDFHFYTMNRADLVFAISHLLGFRPNGAQKAA
>A9DE66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella benthica KT99|TrEMBL
MGFHHAQHSTSLNQSLAELNGDINVSFEFFPPASPEMEKILWNSIRRLEPLKPKFVSVTY
GANSGVRDRTHGVIERIQRETDLLAAPHLTLVDASDEELVELAKHYWNSGIRDIVALRGD
LPDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDARNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDAEIIPGILPVTNFKQLKRFAGMTNVSIPGWLHKQFE
GLDDDPATRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGT
>A0A3A8F8R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WCHAc060007|TrEMBL
MSSLSSYFQQNQFCILVEYLTSLNEIFPVKTQFAGYPSVMTLADRVHSDHDMAPLEASKL
YPQKVEKVLHFAGKGRDIDDFELFLKQAHAINIQNLLLLTGDKLKEHKDGQHGAERSRYL
ESVNAVMAAKKAGGFCIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIITQLGYDIDAL
KQAKAFLTQHDYAQKILACVMPLSLARAKFMLKHKVAGIVITPYMLKVLEDEKLAGLSER
VYLRCALQILICKQLGFAGVDLSACHKPEEQALLESYIEQYRHLDLNALEKLWNELWQIH
TGKELQPELSSFSRPPSSKQLIKYHQLHLMHDALFDSKLAKGMGRFIFKAPFWERAGAAK
TLLKTEYLSKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVEQTQILKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A6L8UD45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSGIKPNRRWQPAYYPFRKEKPGKRLLARLELMIKGPLFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGITPEKLCYVDTTRKCVWYCIYERAQRTGREKTLLEVLPPLDWNKTGTET
WGGVIKQVRAVGTGKFISSLFARDKKRKSEIWDSVFRTIRQPEWWNGDSEYHPPSYAEPV
SELERKLRAGEFVVVTEVTPPLSSDTRKLKENLAMVSQYVAAVNFTDASSAVPRMSGIAC
CKSATDLNIEPVFQITARDATRTSLQATAVGVNNLGIKNILCLTGDNPVVGPHPAADLSM
LDLDSVQMLWILRRMRDEGIYLDGRRMKYPPVFFLGAATSPFASDPALQAIKDQKKVNAG
AQFFQTNLIFEPDRLDPWLENLEKRNVLDKVYILAGVAPLKSYKTALYLHEKVPGVCLPE
KILSRMEKAGEKSAEEGIQIALELISSIKGKKGISGIHIMTLGREEAVGRIVKEAGL
>A0A800LVZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium|TrEMBL
MKSPLLEHLKSSLLVGDGAIGTMLYAGDVPLGVCYDEINRSQPNLVRSIHEEYVAAGAQF
LETNTFGANRFSLAKHNLEHHVEEINRSGVELARQAAGDLAYVAGAVGPTRGMLHQELSQ
EDYAQAYTEQITALAAAHPDAIILETFLNLQDLLTALEACRSVCDLPVICQLAVDQYGRT
DDAFEVTDAFRQLRGRGADVVGINCRSGPKGLLDALSMVPLEEGLILSAFPNAGSPVYID
GRFFYAATPEYFSGSAIRLRDQGVRLIGGCCGTTPEHIRSIAQALKDQQAATSKKVVRIE
VSRPTVQAAQLPTPPQAPTIVELVRQRVTTIVELDPPRNLDFSAIVRGAQALKDAGADAI
TMADNSLAVTRISNMAIGQIVKQEVGLRPFLHISCRDSNLVGMQSHLLGLHALGIDHVLA
VTGDPVKFGDQPGAGNVYDISSFELIRLIKQMNEGLAFSGRPLGGKTNFTVAAAFDPNGD
YLDRRIKRLEKKIDAGADMIMTQPIFDPRQAKQLYAATKHLDFPIFLGVMPLVSTGNTEF
LHNEVPGFVVTDDARARMARFGRGKKARREGIAIAREIMDAVLEYFNGLYLITAFNRYPM
TVELTRHANGKRR
>A0A847L9A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSLVEKIKSAEKTAFSFELLPPLKGNGINGVYNTIDALREFDPKYINITTHRSEVVFKEK
TFGMYEPISIRKRPGTVAVAAAIKNKYNITVVPHIICSGFTKEETEYVLIDLKFLDINDL
LLLRGDKGKHEKKFTSTGHAHATELQEQVNRFNDGFFLDGTKMKIVDEPFSYGMACYPEK
HEEAPNMETELYWAKKKVESGAEYLVTQMFFDNQKYFDYVKKCRDIGINVPIIPGLKPIT
LKNQLTVLPKIFKSEIPEDFARELRKCKTDEDAAEVGVEWCTQQAKELIEHNVPSIHFYT
LMATQSVRRVAKQVY
>A0A7X7C3Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKISELINNVGKTAFSFELLPPLKGNSINKLFKAIDRLKEFDPKYINITTHHSEVIYKED
VNGVFRKVNVRKRPGSVAIAAAIQNKYGIKAIPHIISQGFTQEETEYALIDLSFLGVTDL
LLLRGDAKNLDSHQKSMNSHKYATELQKQVNDFNLGKGLDDTVFTPSDVPFSYGMACYPE
KHEESPNMESEIYYTKMKVDNGADYLVTQMFFDNRKYFEFVDKCRAAGIDVPIIPGIKPI
HLKNQLTVLPRIFRTDIPEELEKELRKCKNDDDAKEVGVEWCIKQCKELIDAGVPSLHFY
SMNAVDSVRRIAQQIY
>A0A6P0W6Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO3A2|TrEMBL
MTNPTNNSFRTAVESGEFLITAEVAPPKGGNPDHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILHQQGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQGTDLFTGAAVDPQLKSWSGLQRRFER
KLEAGAQFFQSQLICDFDRLEKFMNQIAAGSNKPILAGIFLLKSAKNAKFINKNVPGVDI
PEEIIDRLAAADNQLQEGIKIAAEQVKLARQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSPVNDLVFK
>A0A7Y4Z1Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVIDHINNSKSTLFSFELLPPLKGSTLQTIFDTINPLLEFNPAYINVTYHREEVVYKPS
SNGTLIPTVLRRRPGTVGIAAAIQHKYKIDIVPHIICGGFNQLETEDALIDLDFLGIHNV
LAIRGDADKIVGKFEPKIGGHRYAVDLVKQVIAMNHGNYQDETLEKPNPTNFCVGVAGYP
EKHAESPNGFSDIQRLKEKVDAGADYIVTQMFFENKSYFNFVKACRNIGITVPIIPGLKP
VSLKEHLSILPKVFNVELPQDLVKEMEQCCDNRSVKEVGVKWAIEQAKELKRQGVPSIHF
YTMGKSDNIAKIAKEVY
>A0A7S1TND0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrolobus australicus|TrEMBL
VTRSEALLMVSGGSLARKMLPRSLHTAMGVSDAVENLARAKTMIEGSVRAGNIQRPSPEL
WAVANPNVAESKIDDEIARAEQKVRAGACCLVTQPCIDEDRFRVFWDEAKRSKILARAEF
LCGLALFPSTTSVQFWMHLCGVKRSSAAATQLLGRVQAARTKNSSGELAVVDEWERALTH
IEDCVPAEALRGLHVMPVVRSGWRRLPRLLRGSFGNR
>A0A352ME53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MTIVRRWQPALRPFRRITPAGELLAFTERVIKGPLFGCRMCGNCLLQETAFICCMECPKG
LRNGPCGGVTPEKRCYVDETRKCVWYAIYKRAQKKGREKTLLEILPPLDWSKAGTETWAD
VFRQVRKTGTGRFIGSLFSGNEVRKNLIWDSVFKTIRQPEWWKGDSDYHPPAYSEPASDL
ERSFREGKFVVATEVTPPISADSGKLIRDINLVKPYVTAINFTDASSANPKMSALACCKV
ATDNNAEPVYQIAARDTTRTGLQANVIGAGQFGIKNILCVTGDNPIIGPAPTSDMNIVDL
DSVQM
>A0A3M1R249|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium|TrEMBL
MKIRDLLQQSKQSFSFEFFPPKNDSGFEELYKTIGLLKQLHPTFVSVTYGAGGSTRRKTI
ELVARIKHEIQIESMAHLTCVGSTREEIDAILTEIQKRGIENVLALRGDPPRGAQSFVPT
PGGFRYANELVAFIRQKYDFCIGVAGYPEGHQESPSLQQDLENLKRKVDAGGDFIITQLF
FDNRFYFDFVERARRIGITIPIIPGIMPIINFGQIKRFTEMCGASIPSPLLHRLEAIQED
REAVEAYGIEYATLQCQELLANGAPGIHFYTLNRSKATWQIFQNLQRG
>E6QYL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071)|TrEMBL
MPHLTSLIATHNGPFHNYEFFPPLTDPGFVNLLDRIRRLTSPPFQAPLAVSVTWGAGGST
AERSLELAQQIVGMGVEVILHLTCTNMPKDKVDSALQRCKDLGISNILALRGDPPREEEY
AINPTSTPDFFKHADDLVRYIRQKHGDYFCIGVAGYPNPHPDSESEEEDFKWFKAKCDAG
ADFIVTQLFYDVDVFSEWVKTCRAKGIDQPIIPGIMPIQNYASFRRLVNLTKCPVPDSIT
SDLQPISSDDAAVKRYGAELATKMVNQIIESGLVPGVHFCTLNLEKSVRTILDNLGWSAT
SKTSASDGVVKNKLIQDDSQVVNGIQINGKAGKTQNPAEDLSISPSEANQLAQLGLISTT
LPPAPKTGLSAQGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKEWGVP
VSTSDLSALFIAYLHSDPNHLTTPFCDLPLSPESHMILPHLLALNSAKVQHWTVGSQPAV
DAAKSEDGVVGWGPRGGYVFQKAFVEFFVTEDEVNRLTKKVGEEGKGLITMYAANRKGAF
RTNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWTEWSLLYPRNTPSRKL
LEGIANEWWLVSLIHHDYKDQDALWRFLLEDLQ
>A0A354C1H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MTVIELINNSKRPLFTFELLPPLKGHSIERTYTAIDRLIEYEPAYINFTSHRNETIYKER
PDGLLEKKVVRLRPGTIALAAAVKYKYNITVVPHILCGGFTKEETENVLIEMRFLGIDDV
LALRGDPQKGARSFIPEKNGHVHTTDLVNQIADMNRGKYLEENLENADLTHFCIGVAGYP
EKHFEAPNRHVDLENLRKKVEAGASYIVTQMFFDNNKFCRFRDECRKIGITVPIIPGIKP
ISALHDIKLLPQTFHIDLPNDLFSAVSKCKTDTEAREAGIEWATTQSKELLKLGVPGIHY
YTLGRSDNIARIVKATF
>A0A395LYG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thermochlorobacter aerophilum|TrEMBL
MLVRDILRSSKTAFSFEFFPPKQDHEWDKLFHTISDLMTLKPSYVSVTYGAGGSTRERTH
NLVVRIQKETNLTVVSHLTTIGSSREEIYAILKRYDENGIHNILALRGDPPRNIPNWTPA
HQDFKYAAELVAFIKENFPHIGVGVAGFPEGHPATPNRLKEMEYLKMKVDAGADYIVTQL
FFDNHAFYDFCERCEIAGIHVPIVAGIMPITSRQTMYRMAELSPGTCFPAKLLRNINRVQ
DDADVEKVGIHWATEQVSDLMHHGVKGIHFYTLNSSRATLKIYESLGVRDSEQLAA
>A0A0Q8I447|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root682|TrEMBL
MTTGAGRSLGEILRDGGRSFSFEFFPPKDDAGEAQLWDAIRALEPYRPTFVSVTYGAGGA
TRDKTVSITGRIARETELVPMAHLTCVGHTREELEGILDSYVAEGVSHVMALRGDPQEGP
RADWTPTEGGLNYAVDLVDLARSRGDFRVGVAAFPEGHPSAASLDQDADVLVAKAEAGAE
FAVTQMFFRAEDYFGLVERVRARGADIPILPGIMPILNLSAIRRQGELIGTSVPDDIVAR
IAAFEGDPAAVRAEGIKIAAELCDELLAGGAPGLHFYTLNRSKATLEIFEALQITV
>A0A5D2Y1B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium mustelinum|TrEMBL
MKVIDKIQSLSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKIIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DVLVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A5D2XLG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium mustelinum|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGVKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQYPYGQWDDSRNPS
YGALTDHQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSYCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGMFTRRLILSFFAQRKN
>A0A318LIN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. LBP4|TrEMBL
MNDLLRLTTAEEIGRSCAALAAPRYELLPLKGMQEAARSLPPGAVVTMTCSPRHGLERTL
EAAEWLVGAGFQAVPHIAARLVRDPAHLRRLVERMLAAGIDDCFVVGGDADRPAGEYPGG
VELLEAMAAMSPRPARLGVPAYPEGHHRFDDPDLQRVLDAKAALADYVVTQMCFEPSTVL
AWLERQRRSGMTLPVYAGIPGVLDRTRLLSVAMRLGLGASTRVLSRRKGLVGRLLQSDLY
RPDDLLQGLFPALGDGGIAGLHVYTFNQAAATRAWLAAHHAAHCRRHGLEGPEMSEAATV
EQPG
>A0A433SF19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saezia sanguinis|TrEMBL
MALSHAQQLELLNQSVSELKNGTQVSFEFFPPATAEAEENLWSTITKLAALGPRFMSVTY
GHNEQSRQRTHNVIKQIKERTGITAAPHLTCIDASEEEIKNIARDYWNSGIRHIVALRGD
KQPGRQYTNFYANDLVRMLKEVADFEVSVAAYPEMHPEARSAQSDLIALKRKVEAGASRA
ITQFFFDVENYLRFRDRCVGAGIDVEIVPGILPVTNLETLKRFAGLTNVTVPSWLAQRFE
GLENDAMTRLLIGASIAMDQVRVLRREGIRDFHFYTLNRAELTYAICHTLGRRPGMADLP
AKAESVS
>A0A0Q8I5K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root682|TrEMBL
MSRRDRTDVLADLLARVRYEVLPTAKVVDDASASLPVGATVTVTASPAKGLGATLETAEL
LAGAGFDVVPHLAARMIAGPGELAEIAARLREAGISKVFVPSGDATAQAGAYASALQVLE
DLAVAGNPFAEVGVTGYPESHPSIEDDLTIQAMWDKRRHATQIVSNLTFDPAVLAAWVRR
VRARGVDLPILVGLPGPVERVKLLRMASKIGVGESARFLAKNGGLFARMAAPGGYDPLRF
LDRAAATLGRADMNVAGLHLFTFNQVAETERWRIAELARLQDAPPRRRARARVGAPKQSA
S
>A0A842RD76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Heimdallarchaeota archaeon|TrEMBL
MSLNKINRGNRHNAIIELKLTDDTNFQEWFRLIQIASLTAEYISLPDFIPTANMDVIYSS
RILKEKYPFYNQIVNLTLRNPITEIKGKLLALQHNGVKNILVVKGDSNYLNRLYLTYKNG
QEIENNEPYNKLLEKIKSLPYDKYWTKTSLAIKELKEMDTKTNIGSTCNLGHVKEKKWEK
ELRNIELKVRAKTDFFQTQANFDLMRGLEHYDILKKTYPGIPIYFGLMQIRRKKDISFFE
KKLGINIPDQIKKRINKHISNSDIYREGEEIFFDFLDSLIQQDISYVYYALDNKRTLNQL
YRFADKRNLINEEALMHVAETLG
>A0A7J4XCK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides salyersiae|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLCRDIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESIFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDSDIYWLKKKVEAGAEYAVTQLFYDNQRYFEFVERVRKEGIDIPIIPGIKP
FKKASQLSMIPKTFKVDLPDDLVKETLKCKNDAEVQQVGVEWCIKQCRELMAHGVPSIHF
YSIGAVDSIKEVAKEIY
>A0A3L6JI98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MYSCIAQPKEICVSLQTGSFDARLKNSVQSPETKLRRMLRSGKFTVTGEVGPPHGADDDL
VRERTRLVKDYCDAINITDNVRGIPTMSSMACAHFVIQAGAEPVMQMSSRDRNRILFESE
LYGAYALGIRNILFVTGDHTLLGSHPQAKMVYDLDSIQALQLASHLMSGKDLAGEKLEGI
PLFHLGATFNPNADPLELQVWRVEKKRDAGAQFFQTQAIYDTARLEEYMEQIEPLGVKVL
AGVIPLKGPKMARFMNERIPGIRISDEIVNRLESAGAGMKGEEKKEAVRAEGIAVALETI
NRVKMIRGINGIHIMAIGWEESIPELVKASGLYPRPK
>A0A497P9A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MTALEQALTKGEFAVTAEVAPPKGTDVSEMMENAEFLRGKVHAINVTDQQSSVMRLGSLA
SCHLLKEAGFEPVFQLTTRDRNRIALQSDLLSAYALGIENVLCLTGDYVTLGDHPQAKPV
FDLDSVSLLMAAKGLENGTDMAGESLEGAPSFYLGAVVTPGYEPLELQLLKMERKIKAGA
QFFQTQAVYDPEVFRRFMESAKEFGVPVMLGCVLLKSAGMARYMNKNVAGVSVPDSIIDE
MKKTDDKVTTSIKIAARIIRETKEMCQGVHLMPMGWERHVPDILD
>A0A561SQ66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia hierapolitana|TrEMBL
MDLRRRILEGKGEFLLFAVTPPRQAASPERAQEIAEVTLERLRPLGLDGLVLYDIDDESD
RTSQERPFPFLPTMDPADYLARHLSAWDVPAVVYRVVGKYPEADLRSWLLAQDADRVLSV
FVGASSHGKQVATSLTQARQLRAAVRPELTLGGVAIPERHTRRGDEHLRLLAKQAAGCSF
FVTQVVYDVNAAKDLVSDYRYECEARGVTPVPIVFTFSVVGSTKTLEFLSWLGVDVPRWI
QNELRHSADPLVASHEHAFATALDLIAYCRRLGVPFGLNVESVSIRRAEIEQSVSLAAQL
RRELHRSG
>A0A291H0S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium ginsengisoli|TrEMBL
MSATTTLPELERSAPVRHRPALSYELFPARSDVSFERLRETIGHLEATAPDHVSVTSRAG
HGNLARVLELTEHVLAETSLRPLVHLTSIGSTRDQLTTIVHALLDRGVRGLLALRGDVPE
GHRLEDDEIPFARPLVELIREIERERTAGLAGGRVSIGVAAYPHRHPESPTTSHDTEVLV
AKERAGADFAISQVFFDPEVYCGLLERSRRAGIRMPIVPGLVPATNPRRLERLAAMSGVE
PPRELLHRLETAADDAERRRIGVRSTVDLARRVLDAGAPGLHLFTFNSHAEALDVLDHLD
LDRWSAPSQGEPR
>A0A0F5FUE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia geojensis|TrEMBL
MLSSFDLDRPSRQVAEKRPQLQLSFEFFPPKTDAMEERFWESLGKLAPLSPRFVSVTYGA
GGSTRERTLRMVSQIKAQSGVDAAAHLTCVGASRAEVDAVVEGYKAAGINRIVALRGDPP
EGVGQPFVPHPEGYRNAAELVEGIRRIGDFDISVAAYPEKHPQSPSWEADIDNLKRKLDA
GASRAITQMFFNNADYLRYVERARKAGVTAPIVPGIQPIHSFKQISGFAARCGASIPVWI
AERFEGLEDDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRPA
VAV
>A0A1Z9MZC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium TMED204|TrEMBL
MFFDNQKFFEFEKKCREAGIDVPIIPGLKPMATLKQLNLIPHRFHVDXPQELINEIQKAS
DNSAVSEIGIEWCIEQSKELKKHGVPFLHYYSMGKSKNVKKIAXALF
>A9KQY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg)|TrEMBL
MQISKKFGQGKTVFSLEVFPPKKDSPVESIYRVLGELTKLNPDFISVTYGAGGNAADHTT
CDIASYIQSNYGIDALTHLTCVNSTKEDMDTTLEYLKSQGIMNILALRGDRNPEIEPKKD
FTYASNLVEYIKTKGDFHLSGACYPEIHIEASSMEENLEYLKYKVDCGADHLISQLFFDN
DYFFNFLEKARNKGITVPIEAGIMPVVNKKQIERMVTMCGASIPSKLAKILQRYEHQEEA
LRDAGIAYAVEQIMHLVASGVDGIHLYTMNNAYIATKIHEAIFRLL
>A0A1H2KMI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiangella alkaliphila|TrEMBL
MPGGARTIRELLAAGGKSYSFEFFAPKSETAEVAFWQTMRDLERLQPTFVSVTYGAGGTT
REGTVRITEGIARDTTLTVVGHLAAVGHSVAELRNVIGQYADAGVRNFLALRGDPPGNPR
GEWVKHPAGFEYAEDLVRLIRTHGDFCVGVAAFPDKHPRSPDLDTDARFLARKFQAGADY
AITQMFFHADDYLRLRDRVAAAGGVAPIIPGIMPVTNVRQIQRFAELTAADFPAPLARRL
LAVEDDPEAVRAIGVEVATELCERLLSEGVPGLHFITLNKSTATREIYQNLGVGALS
>A0A4Q1ZYM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp. A46|TrEMBL
MTGPYPDPPAFVSFELFPPKTDAGEATLTRVVDQLASAEPAYFSVTYGAGGSTRDRTARV
VDMVRDRTGRPVAHHLTCVGASRDEIDRLARGLHEEGVSRIVALRGDLPEGQRLAPDGYG
DAAELVAGLRRVADFDISVAAYPEVHPEAASVAADLDHLKRKLDAGAARAITQYTFDTEV
ILRFVDRARAAGITAPIVPGIMPVTNFAGLKRFSAMCGATVPDWLARMFEGLDDAPETRA
MVATSVATEQCRLLMEAGLSEFHFYTLNRPEVSLAVCRALGITPAIPSESAA
>A0A4Q7D341|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas orientalis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVNVPAAPHLSCVGDSKADLRGLLTQYKASGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHVEVAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3S2AGV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.006.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
LYRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFRQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>B2JIP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815)|TrEMBL
MNPIELSFEFFPPKTQEGLEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMAK
DGLEAAPHLSCIGSSKESLRAILNEYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFCIEVAAYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVE
DAQKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTNLCRRLVDAKVPGLHFYTLNGAAASKAICERLGV
>A0A4R4W908|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella turkmenica|TrEMBL
MAGDGFELVCEVEPPTRPDLKRVRHQIGVMSPIADAFLIPDNHIGRATVSSVAVANEVQA
MGSRGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDDPAEGARTSQLTVRTMIEQA
RGTSYPGCNPFQVGATTRLRPVPRWKAEADFLFVQVSYDLDELLRWRDSVDLDVPVYAGV
MVLASAEMAHNLAALPQLSIPDGLIAAVEQDRDAGVDHACELIVKLRDSGAFSGVHLVPV
SRYRQVAARLEREL
>A0A117QAQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces antibioticus|TrEMBL
MTTFSFEFFPPKTPKGEQTLWKAIRRIEPLAPDFVSVTYGAGGSSRDRTIEVTKRLVTET
TLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPTGPWQAHPEGFSYAHE
LVELVRSLGEFTIGVAAFPERHPRSADWDSDIRHFVAKCRAGADYAITQMFFHVEDYLRL
RDRVAAAGCDTPIIPEIMPATDVRQITRFAELSGAAFPEQLAHRLEAARDNPADGHRIGV
EYATAMAERLLAEGAPGLHYITLNRSTATLEIHHNVLNSRSAQHVLAAHR
>A0A831LWA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MDKIFHVELQTPKRSSEDIEKDLRVFEDKYHKVVEAGWIVCVTDNPMGLLSYGAMETIDL
LDLPVRPGQLMVHLNTFHSKRKLDEILEAFASAGGRQLLVVSGDGSQRLHRLEPAEVGID
CATVTSVELLRYIDREYPGRFTCGVAFNPYEPLDAELAKMRRKADAGASFVITQPIIGRD
ERLAGLEPFGLPVILDAWMSKKLHLLSECVGHEIPEGTPYDPMGNLRELRRNYPGYGLYL
AILGFKTQYPLLNEIWA
>A0A7J9ID74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium harknessii|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DALVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A848TZW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulosicoccus sp|TrEMBL
MTFEDEPVPGYPLPMRPGHSSPGRLERMLRAGYFVVTSELAPPDSADPAAVYERAAVFDG
YVDAINATDGSGAHCHMGSLAVCALLTRLGYALIQQISCRDKNRIAIQGDILGGAAMGVC
NLLCLSGDGVQTGDHPEAKPVFDLDCMSLLEIARTMRDQSTFQSGRKLDDPPRVFLGAAA
NPFVEPFDWRPQRLAKKIVAGAQFIQTQYCYDLTRLRQYLSDVRELGLQDKVFMIVGVGP
LASARSAEWIRSNVPGVHIPDSIIDRLRGADNQKREGLQLCVELIQEIREMDGVNGVHIM
AYRQEHAVPEIVTRAGILQGRTPWHPRAYDGDATVQQHMENIQ
>R4LMS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes sp. N902-109|TrEMBL
MRAGLGVTACGALRALLARGERSFSFEFFPPKTAAGTRALWDTIRRVEPLAPSFVSVTYG
AGGSSRDRTTEVVERIVNETTLRPVAHLTAIGHPVAELRRIVGQYAEVGVRDVLALRGDP
PGDPNAPWSPHPQGLRYAHELVALVREAGDFSVGVAAFPERHPRSPDWESDIRHFVTKCK
AGADYAITQMFFHVEDYLRLRDRVAAAGCATPIIPEIMPAVDIRQIARFAELSHATFPDE
LATRLAAARDNPAEGQRIGVEYAITMADRLLAEGAPGLHYITLNRSTATLDIHRTVVGSP
STGTLARS
>A0A7J9ZBD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangiales bacterium|TrEMBL
MSAGAEKRVAGRGRGACGTEPAGVATPAGGERRSGRVDPASAGNGRAARSAVGEGRLRAA
IRSGRFAVTAEIGPPRGADADAIRRKAAVLHGHVDAANITDNQGAHARLSSWAGSVLAME
CGVEPVMQLTTRDRNRIALQSDLMSAAALGVPNVLLLSGDHPTFGDHPDATPVFDIDSVQ
LVWTARMMRDHGRLLSGQALRPPPQWLIGAVENPFAPPVGFRAKRLGKKVAAGAEFAQTQ
YVFDLDGFARWMVEVRDLGLDEHCAILPGVGPIRSVRALEYLGSKVPGIHVPDDVVRRMR
AVPGDRVAEEGMRLCVELVQALAEMRGVAGVHVMAFGNEAAVPELVDRAGLPRRADAPVA
AVVKEERA
>A0A840FWE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax guangxiensis|TrEMBL
MSFEFFPTKTPEGAVKLRAVRQQLYARKPQFCSVTYGAGGSTHQGTFGAVQEILAEGVDA
ASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVGFIREET
GRDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDDVRKL
GLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVVTDLC
ARLQEGGAPALHFYTMNQSAATLAVLERLD
>A0A8I2FQ99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
KIACTAMPTARNLDRELEKMEKKINAGADFFQTQVVYDVNKAITFSEKAK
>A0A7C5MRL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MKVTEKIKQGPILSVEILPPDRGKNLQEIFLVMDKLLDYPVDFVSVTRHPPETTYLELPD
RIIKVPRVKRPGSIGITAALLNKYKIEVIPHVLCYGLNKYELEDMLIDLHLIGVRNVFIV
RGEYENHRPINNQDEYHQAVELVRQVAGLNRGQYLYPCENPQATDFCLGVAGYPEKHPES
PNLTEDLKVLKAKVEAGAEFVFTQMVFDFEVYKKFVERAADFSINVPVIPGLKPVVSLQT
VYNLPRKFSVSLPEELVNRLQEARTPGEEFKAGTKYMAGLVEKLLDYGVPGIHVFTMGKG
LATQALLEAIYR
>A0A4Q0XPH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinarcus aquaticus|TrEMBL
MFDALIDKLKNGSYLTLETTPQHEPTMDTIIDKIKQYDLVSKIDGFSATDSPLAKLKYNS
ILAALKLQMEFKKPVITTLTMRDRNKIALQSDIMGANDFDIRSFLCLTGDPAKMSDQPNT
KGVFESNSTMLLKIIKSFNHGMDFAGRPFKVEPKPIYPFAVTNSFSKSFKSLEKKMHKKI
QEGAVGIISQPVYELDNAKQLLESFENAKEHVSDHKQECQLIFGLFPIVKLRTALFLSAQ
VPGIHVPQSWIDKLEKANQKGEEEEKKVGLELNHKLFEDLQKFHPKIHLMTANNFGLANE
LINNR
>A0A4Q8WXM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATGDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPV
>A0A1Q3LM68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium 65-37|TrEMBL
MKVSFEFSPPKTEAAERTLWETVNRLTPLQPTFFSVTYGAGGSTRQRTHETVARLKSDTG
IDAAAHLTCVAATQGEIDDVARAYWDAGIRHIVALRGDPPGGMGGKYSVHPGGYENAAAL
VAGLKKIGPFQISVAGYPEKHPDSADAKADLENLKRKVDAGADRCITQFFFEADDFLRFR
DSAAAAGVRVPVVPGIMPVSNFQGISKMAGLCGSKVPAWLASLFDGLDDDVETRRLIAAT
VAGDLCRRLQSEGVEQFHFYTLNRADLTFAICHLLGVRPR
>A0A2D1IHT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. WMMA2032|TrEMBL
MALGLPSVLPNSQPAIGELIRDGRPTFSFEFFPPKTPAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWVPHPEGVHYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAVTQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PRALAERFERVADDPAAVHRLGVEQAGEMCARLLDEGVPGIHFITLNRSTATREVWQRLR
ADARV
>A0A5C8HX74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium saccharophilum|TrEMBL
MSSETAAAVPFSFEIYPPRTDAGMPALHETIRMLAAAGPEFISVTFGAGGSTGGRSLEVL
THILRQTDVPPLAHLTCVGSSYEEATTLIREFLDAGITRFLALRGDPPADAAEGEEYVGD
LASAAELVQLIDRVQAERAPYTEAPVPGVPGAARVAPRARVEIAVAAFPNGHPRSRHRLE
HIDALLAKQAAGATFAISQLFFHAHDYLGFVELARAAGVTIPILPGIMPITSPSRLRRVV
ELTGEPLPSDLAVALDVEPTAEGRREIGVRHAAALARDVLAGGAGGIHLYAFNNHDNVLA
VLREAGVRTRTEEISA
>A0A260BL22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 06-235-1A|TrEMBL
MAAERLHRRAANIFRQGCPTGVARAATYDLRVSEESVRGRSSRGFVTRTPSIVDRLRTEP
EARIPFSVEFSPPRDAAAEARLWRAVREFEQLQPAFVSMTYGAGGSTRDRTVRVTGQIAE
ETTLLPVAHLTAVSHSVDELRSMVGSYADRGITNILVLRGDPPGDPLGDWEKHPEGVEYA
EELVRLVRDLGDFHVGVASFPEGHHRADDLEQDTKCLVGKLRAGAEYSITQMFFDVDDYL
RLRDRVSAYDAEQGSKPIIPEIMPITSLRSVRRMLELSGTTLPSTLDEKFTRAAGSGPEE
DRAAVREVGIELATNIGERLISEGAPGLHFITLNFARATREVLSNLGLAPARV
>A0A398C3H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmobacter lutimaris|TrEMBL
MTTPRISFEFFPPQTLDASFKLWETVQMLAPLRPTFASVTYGAGGTTRKLTHEAVTTIGR
NYGLNVAAHLTCVEATKAETLEIAAAYADAGVREIVALRGDAPKGATRFTPHPEGFANSV
ELIEALAATGKFTLRVGAYPEPHPDAADTLADVRWLKRKLDAGATSAITQFFFEAETFLR
FRDLCAKEGITAPIIPGILPIENFAGVKKFAARCGAQVPQWLDDAYATAKRDGREELLSV
ALCTELCDELISEGVEDLHFYTLNRPHLTRDVCHALGISPEVALEKVA
>A2QCE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus niger (strain CBS 513.88 / FGSC A1513)|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVEQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDTSSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A258ZY08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 24-66-13|TrEMBL
MAGPIRASREIGKAPVGVSFEFFPPKSEEMERNLWTSVARLAPLAPRFVSVTYGAGGSTR
ERTHATVERLVRETDLAPAAHLTCVAATRAEIDDVVRAYAKAGVKHIVALRGDPTSGVGT
TYEPHPDGYAHACDLVAGIRRLGDFEVSVSAYPEKHPESPSIDADIDYLKEKVDNGATRA
ITQFFFDNDVYFRYLDKVRARGIDIPILPGILPVTNFKQAANFATRTGASVPDWLAKRFE
GLDNDPETRKLIAAAVAAEQATDLVDRGAGDIHFYTLNRADLVYAICHLLGLRDKGVAST
APQAIAV
>A0A8E0BLG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus EMRSA16|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A849M2A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MKVIEHLSKAKEPLISFEIIPPKRGGDIKSLLALVDDLAQYKPPFIDITSHAAEVIYEET
PKGIKRKTKRKRPGTLGICALIQKKYNIDAVPHILCQGFTREETEDFLIDLQYLEIENVL
AVRGDDTVKPVPDGRTTNSYAVDLVRQVNDMNSGKYLEENLLDARPAQFCVGVGGYPEKH
FEAPNLDTDILFLKEKIDAGASYIVTQMFYDNNNFFEFQKKCRAAGITAPIIPGLKILTR
KTNLNSIPRNFYIDLPADLTKEVMKCKGNDVHEVGAEWAAQQVKELIESGVPSIHFYVMQ
NSKAINSLMKKLSF
>A0A662K201|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
QLIKVVKEMRDNGVFQSGDKIVAGKPDVFIGGVANPFAEPYEFRVDRLEMKINAGVDFIQ
TQSVFNLERFNIWMDEVRGRGLDKRVHILAGVTPLKSLKMTERMKFHVPGVDVPDDVYFR
MKKAEDPQIEGFKIALELIDEIKKIKGVHGVHITALFWEEVIPRLVKESNFLPRP
>A0A856CNW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae|TrEMBL
MPSHTRAITDAYSLEVSVKDIGALTKAAPRLLPGSSMFIPYLPGQHDAARLAAAQLVRSL
GFEPMPHLSARRIGAPEELQAFVARLVDEAGVTRCFVIAGDPSTPKGPFADSLSLIETGV
FERSGIRTIGVAGHPEGHPIMRTAEQWDVLERKCRSIQERGMAPLIVTQFGFDADMVVTW
VEALRARGIPHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGNAGPDR
FVDRLASRLTDAHGDIRLHVFPFGGIAQSVAWVAQYRSRASSQDRMSSVRADQA
>A0A1V6NRU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium polonicum|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEATENGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNTDVDQLIDHLKEKVDAGSSF
VVTQMFYDAENFIEWLKKCRAKGITVPIIPGIMPIQTYASFIRRSNWTKVQVPPQWMEAL
EPVKNDDSAVRDIGKTLIADMCRKLFAAGIKHLHFYTMNLAQATQLVLKELDLSPSDESP
IQRPLPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISDIFVNFLTGKLDRLPWSDSPITTEAHDIQEDLLN
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLLDELITRIEKNG
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCHDAASPSRKLIQHVMDDWYLVNIVDNDFHRSNAVFELFNGLEIKDLNVEVAGKPLTNG
HAEPNGVAAN
>A0A399QZH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Henriciella barbarensis|TrEMBL
MSHLSVATRQAEERPRVSFEFFPPKNETMDERLWECVRRLEPMQPDFVSVTYGAGGSTRE
RTHDTVARIASETSLIPAAHLTCVSATKEDVLQTAEDYWEAGVRHIVALRGDSPDGMGAE
WKQAPGGFQNVIELIESLRAHRPDLGKVFEVSVACYPEPHPDTRGWEFDLAHLKAKQDAG
ADRAITQFFFEPDIYFEFLDRARNAGITMPIVPGIMLQPNFNGLKRIAGLCGASVPDWLH
KLYEGLDDDADTRDLITANIAAELCHKLADGGVTQFHFYTLNRANLALSTCHLLGLKPAT
AEAA
>A0A1H3P4X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asanoa ishikariensis|TrEMBL
MRRPAEPPSRYARPVALGLPSILPGSQPSIGDLIREAGPTFSFEFFPPKTPEGEVQLWRA
IRELEPLHPSFVSITYGAGGTTRDTTVSVTERVATETTLLPMAHLTAVNHSVAELRNVIG
RLAAAGIRNILAVRGDPPGNPNGEWVRHPEGVDYAEDLVKIIRESGDFCVGVAAFPYKHP
RSSDIASDTDYFIQKCRAGADFAITQMFFDGDDYLRLRDRVAAAGCDTAILPGVMPVTRM
STIARSEQLSGAPFPPALAEQFARVGDDPEAVRKLGIEQASEMCARLLEEGVPGIHFITL
NRSTATREVWQHLRVDAGV
>A0A350LMJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp|TrEMBL
MTTPRISFEFFPPKTLEASFRLWDTIHTLAPLGPRFVSVTYGAGGTTRELTREAVGALHN
ATGLNVAAHLTCVDASRAETL
>F8CLG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcus fulvus (strain ATCC BAA-855 / HW-1)|TrEMBL
MNPSDPCFSFEFFPPRTDEGEANLLKALEDLAALQPGFVSVTEGAGGSTRTKTVELVLRI
KQETGIEAMAHLTCGGHTPAELRTVLERLSAAKVDNILVLRGDPPKGQAAFEPAPGGFRY
ASEMVRFIREEDFNFCLGGACYPEGHVETPSRDDDLRHLKAKVDAGLDFVVTQLFFDNAF
YFDFVERARRAGINVPIVPGIMPITNYEQIQRFTRLCGATVPMRLALQLERVKDNPEAMA
QLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRARS
>A0A0R1Q3F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus uvarum DSM 19971|TrEMBL
MDNIVTTLDQLQTLKPRFISVTCSNNKNDIEETTLKLAGYINNTLNIPAIAHLPAAYLSA
EQVKRILTELNALNIQQVLALRGDIIPTVPCKKDFRYASDLIKFVHIQEPTFKISGACYP
EIHPESPDLVSDIHYLKQKVDAGCTQLITQLFFDNDKFFGFKENCALAGINVPIIAGIMP
ITNRKQALRLIKTTSAHLPKKFLAIFDKYEHDPESLRTAGLAYAVDQIVDLITRGAEGIH
LYTMNHAETAINIQKTIGSLFNTNEQPSK
>W6RAR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas pseudoalcaligenes (strain CECT 5344)|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFG
EQVITEMCERLLQDGAPGLHFYSMNLAGPSLAIWNNLKLSR
>A0A1G3BFJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RIFCSPHIGHO2_12_FULL_52_36|TrEMBL
MPVLTSGSHLERLLREGRFVVTAELGPPRGAERAVVEKKANLLNGYVDAVNITDCQTSVV
RMSSIASARILLEMGLEPVVQMTCRDRNRIALQSDLLGAWALGMKNLLCLTGDHPKFGDH
PGAKPVFDLDSIHLLHMLKTMREEKKMLSGTPLEGEPRFFLGAAENPFADPFAFRSRRLA
KKITAGAEFIQTQIVYNVDKFARWMEEVREKGLHKRAFILAGVAPLKSAGMAKYMKKNVP
GMDVPDTIISRLEQKKGGSTAGRLEGIEVCIEIIEKLRQIEGLAGIHIMAIEWEEVVAQL
VERAGLLPRPQGRG
>A0A3M1PRF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
ITQPVFDPQILLDFLPKIEHVKIPIIAGVWPLVSLRNAEFMNNEVPGASVPEEYMARMRK
AQEISKEEARAEGIRIAQEAIEKTKPYVQGFQVSAPFGRVEYSMQVLSVLKKFGGSV
>N8TQ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii NIPH 715|TrEMBL
MSKQIPISFEFFPTKTDLGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAADLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVDKVNTGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A848D5S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium boum|TrEMBL
MHQPMFSIEVFPPKRNAPVGTIYDTLDGLQGLNPDFISVTYGTGKSSDRTATARIANTIR
KEYDIPAVAHLTAQYTTREQVDEALDMFKQAGVSAVLALRGDPVPCREPAGAFEHASDLV
AYIREHDPDMTIFGACYPECHPQATDLDEDIRNLKIKVDAGASHLISQLFYDNADFYHFL
DKARAAGIDVPIEAGIMPVTNAKQIRRMVRMCSSRVPLPLESLLDKWGDDPKTLKQAGVI
YASNQIADLVAHGVDGVHLYSMNKPAVTRQIWHNVEDLFSPAHTGTDFA
>A0A1H2W209|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus halophilus|TrEMBL
MSLKTNVTYYPAMPSAFKEKLLSDDFVITSEISPPKGVDVSSAFEEAGLIKDYVDAFNVT
DNQRAVMRMSPLAMGHLLKEQGLDVIMQFTCRDRNRLALQSDLLGAYAMGMENVCIMSGD
YPTKGDNPGAKPVYDLDSVQLLGAMNRLEEGYDIAGNPLESSPSFTKGAVCNTEPDQPLQ
LMKLEKKAHMGIDFFQTQAVYDIGHFETFMDSISHMDVPVLAGLIPLKSAHMARFMNEKI
PGIRVGDELIARMESSTDPAEEGLLICAEQIRELRKVCRGIHLMPIGHYSHITALFEMAG
LHEKN
>A0A7T1MDW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. CBW1002|TrEMBL
MQQLHQALTQGHFAVTAEVTPPRGGDCTRTLEAARALRGLVHAVNVTDGSRAVMRMCSLA
VCRLLLDAGIEPIWQVACRDRNRIALQADLLGAHALGIRNVLCLTGDPVRAGDQPEARPV
NELESVRLLQLVSLLNSGEDPVKGSLPDGPTQLFAGAAADPQSPSWSGLRSRLQRKQEAG
ARFVQTQMVMETDALRRFVDELAAPLGLPVLAGVFLLKSARNAAFVNRVVPGARIPQHLI
ERLADAADPAAEGIAIAAEQVRAFSTIAQGVHLMAVKAEERIPAIIRQAGLGPLGQGQVG
AEKVGHGLLLG
>F7X5I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium meliloti (strain SM11)|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHERCYILVGVG
PMASAKTARWIRSNVPGIHIPDSIIKRLEGAQDQKKEGKQLCIDIMNEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLRGRKPWTREAAPTDALVAERLEHIREGKEENQQQMAEAAAH
HPH
>A0A7W0CUI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea soli|TrEMBL
MTFQVVCEIEPPTTPDLKKVRHQIGTLSSIASSFLIPDNHIGRATVSSVAVAHEVEMMGG
RSIACLNSRDRNLLGFQRDLLTAAAYGVDQFLFVYGDKPTSGNRTSDLTVRSMIEEARAF
DPAFRVGAAAGLKPLPAFKRAADFLFVQASFSLDALLRWRSENPVDVPVYAGVLVLASHN
HARRLAAAIPDIDIPDSLVEALATDRMAGVEAACELVTSIQESGAFAGVHLIPVSRYRDV
ESRLSRSLRA
>A0A399WEK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Brocadia sp|TrEMBL
MDLKSGSNLEKVLQSGQFAVTAELGPPRGADRSVIEKKAGLLKGYGDAFNITDCQTAVVR
MSSIAAGRIVLDAGLEPIIQMTCRDRNRIAIQSDLLGAAALGAKNLLCLTGDHQKFGDHP
MAKGVFDMDSIQLIQMVKAIRDEKKFQGGQELKASEPRFFIGAAENPFADPFKFRAIRLA
KKIAAGADFIQTQIIYNINKFKDWMKMVTDMGLHEKAFILAGVAPLKSAGMARHMKHNVP
GMDVPDEVINRMTAVSAAKKGKEEGIKICLEVIEQIREIKGIAGIHIMAVEWEEAVPEIV
KETRLYPRPLL
>A0A3S4AK38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MVLKNEVRDRNIRVSFEFFPPKSEEMEGQLWHTVSQLQDWEPDFVSVTYGAGGTTKAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTTADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKIAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRPAAKSAGAAA
>A0A009I6W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 1295259|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A357M8F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp|TrEMBL
PEKISEIAQKQVERLKNVDLDALILYDVQEEAERVDHERPYPYLPTIDPAIYGDKYLRQV
EIPKIIYRCVGNDTRASFADWIKTDESEDRFSVYVGASSSKQEVKLNLPDAYKLSKQLNS
NLNFGGVVIPERHIKKNDEHIRVVEKINNGCNFFITQATYNVEASKNLLSDLYYYYTNQG
FEMVPILFNLAPCGTAKTLQFMKWLGISIPGWLENELKYSNDILDKSIQLSQKIFEELFE
FGLEKGIPIGCSIESVSTTKLEIEASIQLAKDVKAFLDKKLLSLESR
>A0A5C5GEQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagovum pacificum|TrEMBL
MPTPSVSFEFFPPKNLEGSFRLWDCVNALSALSPEFVSVTYGAGGTTRQLTHEAVGTIHK
TSGLNVAAHLTCVNASREETLEIAKGYSEVGVNRIVALRGDPPKGEGSFTAHPDGFANSV
ELIEALADTGKFLIHVGAYPEKHPDAADTAADVEYLKRKIDAGATSAITQFFFEAETFFR
FRDACEKAGIDAPIVPGILPIENWNGARKFANMTGTSIPQVVSDAFDHAETQADKDLLAT
ALATELCDDLMQGGVEHLHFYTLNKPDLTRDVCHALGIKPKVELRDVA
>A0A1X3CQK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria zoodegmatis|TrEMBL
MTLHNQQRKKLSFEFFPTRTPEGRAKQVITRKQLSQFHPEFFSCTSGAGGSTRDGTMQAI
QDILSEGIAAAPHLPCVGMHAQEIIDLLNEYKALGVRHIVALRGDIPSGMGAGSDGLRYA
NELVSLIKTEFNNDFHIEVAAYPEYHPQSRSAEDDINNFVRKVKAGADSAITQYFYNADA
YFRFVDDVRGRGVDIPIIPGIMPIASFSKLSRFSDTCGAEIPRWLRLKLQSYADDTASIK
ALALDVVTEMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>A0A0H3MXJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis (strain BM407)|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINKNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A479ZZT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerospermopsis reniformis|TrEMBL
MQDSHKTSTLNNFRKAVQAGEFLVTAEVAPPKGGNITHTIEMAATLKGRVHAVNITDGSR
AVLGMSPLAASAILLQHGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPDAKAVFDLESIRLLQLIRNMNQGVDFNHKTLNDGALDLFAGAAVDPQSKSWSGLQS
RFEKKIEAGAQFFQSQLITDFEKLEKFMDQIASRYNKPILAGIFLLKSAKNAQFINRMVP
GVNIPDHIIERLEKAKHPLQEGMKIAAEQVQMARGLCQGVHIMAVKKEEAIAPILDLAGV
EKVS
>A0A3G6MT42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium shandongense|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTAGGHASAMDLVHQINNLGRGKYLHNEDQECDEHNKFCVGVAG
YPEKHIEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVNKAREMGINVPIIPGI
KPIATKKHLKLLPQVFKIDLPEELISEVENAKNNDAVKQIGIEWAITQCRELLDFGVPVL
HFYSMGKSDNIKRVAGELF
>A0A0J6XNF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces roseus|TrEMBL
MSARPTPYPERPAQAPVIGGGLAELLRRVRYEVLPAKATEDKVLAHVPAGVPVTVTASPA
KGIGPTLDLAVRLAGHGYRVVPHLPARQITDAGHLSDIVDRLVAAGIEDVFVPAGDADPP
AGAYDAALPVLRRLGELGSPFAHVGITGYPESHPLIADEVAVRAMSDKQPHATYIVSNLC
FDPATLRQWLGRVRRRQVLLPVHVGVAGPVERAKLLSMATKIGVGESAKFLTRHPSWFLR
FAAPGGYSPERLLRRSAPALGAPESGVAGLHLFTFNQIAETERWRRAVLDRLAG
>A0A6V8N9Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomonas limicola|TrEMBL
MGAKFLDRVRQEVLVGDGAIGTMLYAKGVSLEANFEHLNLVRPQLVLELHDEYLAAGAQV
IETNTFGANFVKLDAIGLGPKVAEINRQGAKLARQAAAGKDVFVAGSLGPLGRGKAELSA
EQLRDCFRTQSLALAEGGVDLLILETFTELEELELAVLAVKETGLPVVANLAFGEGARLS
GGFSAEDAAQRLASAGADLIGANCGAGPLELLATLKRLAQASDLPLAAYPNSGFPEYLDG
RYIYRATPDYFAGMAREMVEAGASLVGGCCGTTPEHVREVARQLAGLKPVARPASRSVGT
VQVGTGTASTEQGFLTHWGTRKVITVELDPPKGLDCSKVVAGSRALKEAGADAINLAENP
LARVRMGNLALAALVRREVGIEVIAHVTCRDRNLIGLQSDLMGASLLGISSILAVTGDPA
NLGEDAGASSVFDLNSFTLIKLLNDLNRGVNALGNPIGSGTGFTIGAAFNPNVQKMEVQV
GRLARKVANGAQFAQTQPIYDIARAEEMVELTAPLGIPVLPGVLPLVSGRNAEFLHNEVP
GIVIPDEIRRRMAGRSGDDGVREGLAIASEFIDAIFDRVGGFYLIPPFGKHEIATELVKY
LKAKEKQ
>A0A6H9LI54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTEHIANGKGKTQFSFEILPPLKGQNIQSIFDNIDPLMEFKPPFIDVTYHREEYVYKE
MENGLLQKKVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKTETYFTPEKEGHRYANELVQQIDALNRGEYLDEEIMNQAQTDFCIGVAGY
PEKHMEAPNMESDLHFLKKKLKNGAAYIVTQMFFDNNKYFEFVDKCRTAGITAPIIPGLK
PISTKKQLNLIPQRFNADLPESLIKEVLKCENNQQVKEVGIEWCVEQSKELITENVPFLH
YYSMGKSDNIKAIARQLF
>A0A8J8KA10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frigoriflavimonas asaccharolytica|TrEMBL
MKITDHIKNANGKTLFSLEVIPPEKGSGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYIN
KGNGLMERKITRMRPGTLGICSAIQHKYNVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKGEKYFTPSEGGHENALGLVHQMNDLGRGKYLHDENLPSDFNKFCIGVAGY
PEKHLEAPSMNYDLKWLKEKVDAGADYVVTQMFFDNQKFFKFVEIAREAGITVPIIPGIK
PIATKKHLKLLPQVFNIDMPEDLISAIDGAKNNAAVKEIGIEWAISQCKELLDYGVDVLH
FYSMGKSDNIKKIASELF
>A0A2K8MLQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Cra20|TrEMBL
MSIPQIHPAWDKPPAGVTDGYSLEMTAKDVPALRAAAPRIAPETPIAITFLPNETMDARI
AAAAEVRALGFEPMPHLSARRIASRAELEAIVAGTVAEAGVKRVFLVAGDPPVPAGPFED
TMALLRTGLFERNGITAVGVAGHPEGHPTMSEAQCWEALEIKRAEITARGMATLIVTQFG
FDADPFIAWLLALRARGIDAPVRIGVPGPAGIKTLLRYAAHCGVGASASVMTKYGVSITR
LLGTAGPDKLVDRLAARLTPVHGPVRLHFYPFGGLERTVDWIEDYAGKG
>A0A1R1IMD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. ZS04|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRSAVNVSFEFFPPKSDEAEANLWKAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIEGYKTIGVDH
IVALRGDPPGAAGIGGAYTPRADGYANATELTAALSRIGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLKRMT
AACGAALPDWLAGHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAVA
>A0A0B2C607|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas cannabis pv. cannabis|TrEMBL
MMHPATPRPASTLTDAYSLEVGAHDIAALSAVAPRIVPGTLIAIPSLPGQDDATRLAAAQ
RVRGLGFAPMPHLSARRIASLDALQAFVRRAVDDAGVAHCLVVAGDPSLPLGPYPDSLAL
IATGVFGRAGIKTIAVAGHPEGHPAMQADDRWTVLQRKCRSIAERGMAPLIVTQFAFDAD
LVLTWLNALRAHGIEAPVRVGVPGPAGVAVLARYAARCGVGASAAMLSKYGISLGKLLGT
AGPDHFVDRLAAGLTPAHGDVRLHMFPFGGIARSLAWAEHYRSRTALAAATDLPTT
>A0A1W9NWY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Cloacimonas sp. 4484_209|TrEMBL
MKDCQSSICFCYLRSPGQRSGIYKGDYHKLHSLLKALLEAGVDNVLALRGDLPQDKTFDY
KEGEFKHASDLISFLRKYYPQFGIAVASYPEGHPESLSLEEDLKFLKLKLDRGADFAITQ
LFFDNNIYWKFLEKARNIGIDKPIIPGILPVTNLKTLERILSQCGVDGKDKAV
>A0A355BEX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTQHLEIANGNPLFSFEILPPLKGQNMQSIFDNIDPLMEFKPPFIDVTYHREEYEFKE
LPNGLLQKKVVKKRPGTVGICAAIQNRYSVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKNETYFRPEKEGNEFASDLVKQISNLNKGIYLDEDLQNSAATNFCIGVSGY
PEKHMEAPSIDSDIHFLKQKIKNGADYIITQILFDNQKFLAFVEKCRNAGINVPIIPGLK
PISTKKQLNLIPHRFSLEMPDDL
>A0A0D1C0X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ustilago maydis (strain 521 / FGSC 9021)|TrEMBL
MSNGIDSPLPPKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADL
GPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGC
RNILALRGDPPAGQSEWEPHAAGFTRAKELVEYIREQYGDYFAIAVAGFPEGHPEAIDGP
ELELERLKEKIEAGADFIFTQMFYDFDIFAKWVKDVRAAGINCPIIPGVMPIQTYGGFQR
ATARFGTLVPQYFHDALDPVRDDDQKVREIGTRLVGEMCKKIVGTGLGISGLHIYTMNLE
KGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRREEKIRPIFWANRAKSYVNRTETWDEFP
NGRWGDARSPAYGDVDAYGVKLRYSNEEAKEMWGAPTCLDDVKTLFQQFCAGQVKALPWS
ETPVARETSVISDKLAKMNQLGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEFF
VSPEDLDALIARIEADPQITYHAVNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVES
ISFLAWKDEAYEIGRNWAKVYEPTSPSRKFLEDMFNSYFLVNVVHNDFKANDSIFEPFLS
ASEVTSAVNGSLSGLASAVSNAAGHVTNSISSPANAISNGNASSPAPAAS
>A0A2S7PJA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rutstroemia sp. NJR-2017a WRK4|TrEMBL
MHVKDMLSDAQRAGTPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKDKIDEALRNAYKAGCTNILALRGDPPREKEK
WVATEEGFRYAKDLVRYIRQTYGNHFDIGVAGYPEGCDDQDDPELLLDHLKEKVDAGATF
IVTQMFYDVDNFIEWLGKVKAKGINAVIIPGIMPINTYASFLRRCNHMGCRIPPKWSAAL
EEVKNDDAAVRNIGKDLVVEMCRQILNAGVNHLHFYTMNLAQATRMVLEDLGLTPSSNRP
LKQALPWRQSLGLGRRAEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNRKLWGEPASVRDIAEIFVRYLQNDIESLPWSEAPITSEADAIKADLIG
LNYRGFLTINSQPAVDGAKSSDPVYGWGPTNGYVYQKAYLELLVSPDVIEELINRIQRDP
DLTFYAVNKAGELRSNASNDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHSSLSPSRQLIESVMGSWYLVNIVHNDFHKSHGLFPLFDGLTVENIDKPFESVAQDG
EANGTTNGAEAAPLKNGDANGHANGH
>A0A3N5SKX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
VQFPGQPEKVWTPQEAMQMDADDYLSIEPGDVTSVSQSMEVLKLTEKLDEKLDEKKNSLK
EAILNPNVFCVTWEQIPGRGAFEIQQEQVFDNVAKAAEMGKIHAISVTDNPGGNPAISTE
MLCAEIKKVGTEPLVHLACRDKNRSQIESMLYGLAASGVRNILALSGDFPSPEGFEGKPK
PVFDMDPVNVVRLVEAMNRGLEHFSMGKKVTLAPTDLFAGVCVSPFKQVEAELMAQYYKL
KKKIEAGGKFIITQIGYDARKYHELLQWLRANHFDVPVLVNVYVLPYGAAKLMNSNKIPG
CVVTDKLVAELAEEAKAPDKGKGARLLRSAKLYAIAKGMGYAGAHIGGHGITSDMVEFII
SKGEELSKDWEKLVPEFDYPQPSGFYLFEKDPKTGLNTDVLAKRPSKPSSPLIYRFSRMA
HVTLFEEKSWVFKMMRPIARWADVSPKARAVLEFFEHMAKTALFHCLNCGDCALFDVAFV
CPMSQCPKNQRNGACGGSYQGWCEVYPNEKK
>A0A7C8FBQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLVRDILEKNRISFSFEFFPPKDEPGWENLFANISDLMPLKPAYVSVTYGAGGSTRDRTH
KLIVRIQQETNLTVVSHLTCVGSSRAETGEILRNYTESGVENILALRGDPPKGQTDFVQP
QDGFAYAADLVAFIKKNFPRIGVGVAGFPEGHPATPNRLLEMDYLKAKVDAGADYIVTQL
FFDNRDFYDFRDRCTLAGITVPIIAGLMPITTKSGMVRMAELAAGARIPASLLRALDRAR
SDEQVEKVGVHWASEQVRDLIDNEVRGIHFYTLNHSREALDIYQSLGVEDSVQLGG
>A0A7C1RUK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MISAFKNALDSGKFVVTSEVAPPKGTNLDKMAHHIELLKDRVDAMNITDHQSSVMRFPSL
GGALLVKEMGGEPILQMTCRDRNRMALEADLLFASQRGINNVLCLTGDAVMFGDHKEAKG
VFDLDSSQLVAAVRRMERGEDLGGNKLEGGVSFCVGAIVTPEADPLEPQLIKFEKKMEAG
AEFIQTQAVYDLDNFKEFMDYARQFPVKILAGIILLTSAPMARFMNKNVAGVNVPQGLID
EMASAPKGRALAKGIEIAGRMIRRIREEKMCHGVHIMAIGREEVVPEIMAAAGLD
>A0A7C5AXG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Solibacter sp|TrEMBL
MPSNELREALESGRFIYTAELVLGRDHTVGEAETFISDAAADPKGLRVISLTDLPGGNPA
LPPEAFAQAVLERGLTPITHLSGKDGNRSFIEGRLHALARTGVENILALTGDAQREGFAG
RGKPVYDLDSVLILRLVEAMREGLSYALGVRTVKTSPFDFFAGAAVNPYKVREPDQMMQF
YKMELKIACGARFLITQLGFNLRKLVELRRYLEREGLTHVPVLANVYVPTAAIARMMQSG
ALAGCVVSDALLRRLESEKKPQRLERAALMVAAVRELGFAGAHIGGFGLTHRDFRAIIDR
AAEIGGDWRRRLDELIFEYPGEFYLLPAGSDGLSDPAGQYQLSEPAQRPRWRQRVAALSH
RLLIAKGSPGERFFSRRLNSTFWSRLLEVSSLYRRAALGCAGCGDCIQDHLDYAGCSMRW
CYKELRNGPCGGSRPNGSCEARRELPCIWNVIYECSRAAGHDPRRFAHTLVPPRDWSLDG
TNALANRLAGVDNLGKRQTIHVHHR
>A0A7V2GDL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKIRDMLRQNKFTLSFEVFPPKREGNVESLYSTVDNLIRCNPHFISVTYGAGGSTRDKTV
EIASHIKNEHGQEVLAHLTCVGTTRHDIGRILDDLKDKHLENILALRGDPPQGKDVFMKT
KGGFGYANELVEFIKEHDDFCIGVAGYPEKHLEAPSMAADMENLKRKVDAGGNFIITQLF
FINDVFHRFRDLAVNRKISVPIIPGIFPLFNYSQISRIGSLCDPAIPSQLLDKLYKVRDK
NEEVQKYGIEHAIRQCEDLLSNEVSGLHFCCMNKSDHVLEIVRQLSIPTQKTTSADEYY
>A0A7C2X1D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKISDILASDRFSLSFEVFPPKRDGNIDNLYKTIEELETAHPDFISVTYGAGGGTRDTTV
EIASKIKNVLGVETLAHLTCVQATSADIADILEEFKRNNLENILALRGDPPANTGTFIKT
SGGFGFANELVNFIRSQGDFCIGVAGYPEVHIEAPSAEADMENLKRKVDAGGEFIITQVF
FENDAFYRFRDRALKVGINVPVIPGIFPIFNTKQIPKITELSNSKIPSSLLDKLEKASDW
PEEAEKYGVEFAVRQAADLVRNDAVGLHFCSMNRSSHVLKILSEMELPRRHPARQQNG
>A0A7C0XAR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEERLAQMDSEYKVKGINRSFVVTFELVPARASKGKAIDEILRFAREAADDGLISALSIT
DNAGGHPALTPRALGSEIMDFGIDPIVHFSCKDKNRNLVESQLFVLDRSGIKNLLVLTGD
YPRYGFMGDAKPVFDLDSVQVLSMISDMNQGFVLNVRAPLGGVKLPPMSFHAGCVVSPFK
RLESELIPQYLKLKRKLDAGARFVITQMGFDVRKFDELRRFMDREGLKVPLLGTVFIPTI
KLARILCRGEIPGCVLPGRLLERMEKEALSDDKGESAGLERAARLVSILKGLGYEGAHIS
GPGLKYAHVKWVVERAMEIGERWKSFTYGFLFPEECSFWYFKEDPETSLNCDEPNPVSDI
GLSLKDSLGLSLGRLFHGLAFDPGRPLFNSLRRMAGWIDDSSSKNRFTSFEYRVKEWLYD
CRRCGDCTLGEMGFLCPQSQCSKFLLNGPCGGSRDGWCEVWPGRRRCFYVMVYERLRCLG
EQERLAGPRLPPRDWALDSTSSWLNFYLGRDHHRIG
>A0A7V8YFX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLDFRAALTRQVVVFDGAMGTEIYRRGVFINQAFEALNLTSPELVRSIHEAYLRAGAQVL
TTNTYGAGRKRMREFGLDDQFEAINAAGVRIAREVAGERAWIAASIGPLGRTIAPVGRLE
PGQAFAAFKEQALALAGAKPDLFVLETFHDPRELWQAVRAVRSVSELPIAACIAFSADAN
GNPPPDAAHVLHQVSSWPVEVVGVNCGAGPRTLLEIVEAAAPLVKKPILVMPNAGHPQDV
DGRQIYLASPEYMAEYARRFVQKGARAVGGCCGTTPEMIKEIRTFIRSVSPGIEVLQVHT
PPSEERVVSLEPTPVAKRTTFAQRLMSGKFCISVELDPPRGLNPAKSVEGAAFLYEHGID
VINIADGPRAVARMGPTPLAYLAKQRCGIESVVHYCCRDRNLLAMQMDLIGANALGLRNI
LAVTGDPPKMGSYPNATAVFDVDSIGLIAFIQMLNRGLDFAGRPLGKGEKTELFVGAGCN
PAHVDLDLEVERFGRKIEAGAEFFFSQPVYDEDILFRFLERTERFPKVPFLVGILPLASY
KNAEFLHNEVPGMAVPAPVLDRLRKAESRDAQRQVGIEVARETLTAVRHHPRINGAYIYP
PFGSYQRVLDVVEGIR
>A0A7Y3FLJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MNVTNLNATELAAVRNVIENLHYELIPLSNVIEQAAFLPERATVSVTASPAKGMQATIDL
SLQLQDMGMHVIPHFSARLTTDRAELEANLKAIDKAGIHRVFIVGGDADPPGEFFDAFSL
LQAIDDIGHTIDSFGITGYPEGHPIISDELLEQAIVDKAPFAQYITTQMCFEPDTITDWI
GHQRDRGIELPVYLGIPGSAELKKLLGISARIGVGDSIKFAAKNPKLIGRLVKPGGYSPD
ALILGLAHALTDDRINIEGFHCYTFNQVERTEEWRRDMLEALS
>A0A7V6B6B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLGALKELLDKGVVVFDGAMGTLLYARGVYINQNFDALNLFRPDLVEKVHRDYLLAGAMV
LTTNTFGANRIKLGRYGLEDKLKEINKAGVALARRASGGKALVAGSVGPTGVVPDIFDKS
QLALLRDVFREQIEALLDAQVDILVFETFRHTLEINLAIEEARKVFDGCIIGQMALDDSL
QTADGKSPERVAQLLRDFGADIVGLNCGIGPAKMAEAISGMVCAGVPVIAQPNAGYPRRL
EGRVMYMATPEYLGEHTKQYLRAGAKIVGGCCGTTPEHIRQVANEARLFVGGKIEIPKET
VAIEVSDAEMRVPLPVEERSEFGRVLKDGWVISVEIDPPPGTDATKVLEAVKGLASAGIR
FINVADGPRAMARMSALSLAKLILDSAGIETILHVTCRDRNLLGIQADLLGAWALGIKNL
LVITGDPTKLGDYPMATSVYDLDSIGLLRLVSMLNRGLEPSSRRMKGATGFVKGCGVEPG
AKDLDREVERLFKKVEAGAEFVMTQPVFDAEVFLNFLEKVKGIHIPIIMGVLPLVSYRNA
EFLDNEVPGMHIPKDIKERMRKADKGEPARREGVAIARELVSQMKDKVNGIYIMPLLGHF
EMVKEIVEGMV
>A0A7V3KCD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSKLKEALEAGKFALTGELGPPKGVDIQAMMEEAEKYLKGRVLAINVTDNQSSVMRIGSL
GICARLVQAGFEPIFQITCRDRNRLAIQSDILSAYILGIRNILALTGDHPSLGDHPGAKC
VFDLDSVSLLYTITKLKSGKDLSGNDLIGAPKDIFPGASVTPGADPLEPQLIKMEKKVEA
GARFFQTQAIYEPSKFEKFMKSAQKLKVPVLAGIVIVKSPAMAKYMNEKVAGVFVPDEII
KPLSSASKDDRPKVAIDLMANLMKELKPMCQGFHIMAMGWEKYVPELIQKAGLA
>A0A7C3N2M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEVLKLTEKIDQKLGERINSLKAAILDRNTFCVTWEQIPGRGAFEMQQETVFDNVAKAAE
IGRIHAISVTDNPGGNPAISTEMLCAEIKKLGTEPLVHLACRDKNRSQIESMLYGLAASG
VRNILALTGDYPSPEGFEGKPKPVFDMDPVNVVRLVEAMNKGLEHFAMGKKVRLAPTELF
VGVCVSPFKQLESEVMAQYYKLKKKIEAGARFIITQIGYDARKYHELLQWLRLNRFDIPV
LANVYVLPYSTAKLMNSNRIPGCVVTDKLVAELAEEAKALDKGKAARLLRSAKLYALAKG
MGYAGAHIGGHGITSDMVEFIITKGEELAKDWEKLVPEFDYPQPGGFYLFEKDPKTGLNT
ETFSKRPSKPSPPMIYRFSRLAHVTLFEEKSWVFKMLRPVACWVDRSPRARRVLEFLEHM
AKTALFHCLNCGDCALFDVAFVCPMSQCPKNQRNGACGGSYQGWCEVYPNEKKCVWVQAY
DRLKAYGEEKTLGDYIVPPCNWELWQTSSWLNFYMGRDHTAKRLGIRPPEKKGAERA
>A0A7C1RSV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRKTKTPSRLEKVLAAGHLAVTSECGPPRGSDPAVIIKKAEMIKDHVDAINVTDNQTAMT
RLCSLASVIHLKAMGLEPVLQMVVRDRNRIALQSDILGAASFDINNILCLSGDHQKFGDC
PDAQNVYDIDSMQLIRMARHMRDEGKFVGGDDINRPPRMFVGAAANPFADPFEIRVSRLA
KKIEAGAEFIQTQCIYNLDKFELWLKQARERGLHEKAFILAGITPMKSAGMARYMKNRVP
GMDVPDELIKRLSSVPPKKQPEEGIHICVETIERLKEVEGVSGFHIMAIEWEERVPEIVE
RSGLYPRPKTG
>A0A3S9LCJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella khirikhana|TrEMBL
MAFHHAQHANSLNQNLAEVGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTYG
ANSGVRDRTHGVIERIQNETKLVAAPHLTLVDASDEELLALAKNYWNSGIRNIVALRGDL
PAGSPKPTRFAADLVRLLKSVADFDISVAAYPEVHPEAANAQADLVNLKRKIDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAAMTNVSLPGWLHRQFEG
LENDAATRQLVGANVAIDMVKVLAREGVKDFHFYTLNRAELTYAICHTLGVRPKQD
>A0A7V9GI92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MTRIADLLAAGPTTSFEFFPPKTDAAAVQLEKAVQELAPLQPSFVSVTYGALGSTRDRTR
EVVTRINDDHPFPAMAHLTCVGHTRAEVVALLETYAAAGVHNVLALGGDPPADGRDPGGE
FTHACELLELVQAVGGFSVGVAAHPELHPRSPDRVSDRRYLAEKLAAADFAVTQFFFDAA
HYVELLDELAALGVDKPVIPGVLPVTNVAGLRRMAAMNGTDVPAALVTRLDAVADDPAAV
AAIGVEVAVELCTALLAAGAPGLHLYTMNRSSSIRAVLAALGGGPPV
>A0A7V7D131|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
PPRLFVGAAANPFADPFEIRVPRLAKKIAAGAEFIQTQCIYNLEKFELWMKLARDRGLHE
KVYIMGGVTPLRSAGMAKYMKNRVPGMDVPDEVVARMAGVPKEKQAQEGIDICVETIQRL
KECEGVRGFHIMAIEWEEKVPEIVERSGLYPRPSHS
>A0A2A3MTP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. D43FB|TrEMBL
MTLPSIHPNWDLPPKGMTDGYSLEITAKDIDALREAAPTMAAETPVAVTFLPGESLEARI
AAAKLVRSLGFEPMPHFSARRLESGDDFETYLAAVVREAGVQRCFVIAGDPPEAAGPYSD
SMALIRTGAFERAGIKAIGVGGHPEGHPNMTPDQCFAVLTEKCAEIEQRGMAPLIVTQFS
FDAAPVLSWLADLRQRGIDAPVRIGIPGPAGIKTLMRFAARCGVGASASVLTKYGISITK
LIGTAGPDKLVDALASGLGDQHGKVRLHFYPFGGLTKTVEWINDYTARH
>A0A1L7T014|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium mangiferae|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLKLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLASDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A0R0LT78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrovum sp. JA12|TrEMBL
MESQKGFAKLFSFEFFPPKTAEGVEKLRHTQRQLSQLHPAFFSVTFGAGGSTREGTLGAV
LDILKAGDSAAPHISCIGSTKAMLKDTLDQYLEHGIRHVVALRGDLPSGTYGGGDFRYAS
ELVRFIREEVSQELIIEVAAYPETHPQARSAQEDLIHFKEKVVAGANAAITQYFYNPDAY
FDFIERCEQQHITIPIVPGIMPIGNFSQLSRFSEACGAEIPRWIRQKMLGYGDDSASIRA
FGLDVVTHLCDTLLSAGAPGLHFYTMNSAGLTSVIWDRLHLSSYR
>A0A534Y141|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRITDMLRFAAERGEPVFSFEFFPPRNDAGVAALFETLRALRPLAPSFVSVTWGAGGSSR
GRTLEMVTRIKRETEIEAMAHLTCVGASRKELEEQLAVICDAGITNVLALRGDPPRGQRE
FIVHPEGLAHATDLVQLAREVADKRGVSLCIGGACYPEGHPETRDLAKDLRHCKQKADAG
ADFLITQLFFDNRRYFEFLGRARAAGIDLPIIPGIMPITNVDQIERFTALCGAHIPAGLS
AALRARRDDPDAALQLGVAYAALQCAYLLRGGAPGAHFYTLNRSTATRAILAALRAQEPW
RDA
>A0A506P171|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea anthophila|TrEMBL
MSFFHANQREALNQSLAELNGRINVSFEFFPPRSGEMEETLWRSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRAIAQDYWHNGIRHIVALRGD
LPEGGGRPEMYGSDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMNAMFA
GLDEDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAVAA
>A0A135IAY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterovibrio coralii|TrEMBL
MIMDSLSGSDNRVPHQADLAKAASSLVANASIEATPKQIADLGNKAPDWMQEGMRIYVPA
LPNADFGDAIKASETLLAWGMKPVPHLPARIVPDTETLTGWLASMQRIGVKEILLIAGDT
ETPAGPFPDTLALIKSGLLSEYGLTGFGVAGHPEGHPHADDEALLNAMRYKRDYAVAHDL
DFWVVTQFSFDEESLISWLDRHQAILESVPVYLGLAGPTRLKNLLAYAAQCGVATSAKAL
SKNMNAMRLLRPWKPDALFQALSKYKASHSATPLQGVHLFPFGGLQQSNQWLSSAHLLVS
>A0A1S6EE42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus delbrueckii subsp. bulgaricus|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADYLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILNRYQNSEEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNNADIAERIWNATKSVFDAANARTRTTIKHRS
>A0A534NFG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRITDMLRFAADRGEPVVSFEFFPPKNDAGVAALFETLLALRPLGPSFVSVTWGAGGSSR
GRTLEMVTRIKRETEIEAMAHLTCVGASRKELEEQLAVICDAGITNVLALRGDPPRGQRE
FIVHPDGLAHATDLVKLAREVADKRGVSLCIGGACYPEGHPETRDLTKDLRHCKQKVDAG
ADFLITQLFFDNRRYFEFLGRARAAGIEVPILPGIMPITNVDQIERFTALCGAHIPPGLS
AALRARRDDPDAALQLGVAYAALQCAYLLRGGAPGIHFYTLNRSSATRAILAALRAQEPW
REA
>A0A2T4IU82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium helmanticense|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHDDITETQVDMVK
TAH
>A0A2D5DJP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingorhabdus sp|TrEMBL
MTLSVAQLXEAQFATGEPLFAGLPGDAEISFEFFPPKSEKMEEKLWDSILTLAPLEPRFV
SVTYGAGGSTRERTHKTVARIIRETGLPAAAHLTCVEASKAEIREVAEQYWEAGVRHIVA
LRGDPPSEGTKFVPHPEGYASAAELVKGLKEIADFEISVAAYPETHPEADCPDSDLDNLK
RKLDAGASRAITQFFFQSDSFFRFRDACAAHGIDQEIVPGILPVSNVAQTRKFAGMCGAE
IPDWMNRLFDGLDDMPDARQLVAATVAAEMCRRLYAGGVRQFHFYTLNRAELAYAIXHLL
GKRPAGTASKEKAA
>A0A5C1B6B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. F3-2|TrEMBL
MNAFRPSRHGSRRPSVSFEFFPPKTAEMEVALWESVRRLEPLGPSFVSVTYGAGGSTRER
THATVKRMIEETALKPAAHLTCVSASKAEVDEVIRSYWDAGVRHVVALRGDPAGGLGTTY
EAHPEGYQQTSDLVAGLKSIGDFEITVSAYPEKHPEAASLDADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRARGIEIPIVPGIVPVQNFKQTAGFARRTGASVPQWLADRFEGL
EDDPATRRLVAAAVCAEQVLDLIDRGVTDLHFYTMNKADLVYAICHLVGLKPEKLAAQAV
AAE
>A0A2A9PEY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps unilateralis|TrEMBL
MHIKQMLAEAANGRQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQSVCGLETCMHLTCTDMGLEKVNDALNKAYKAGCTNILALRGDPPRDQQE
WTATDDGFQFARDLVKHIRDTYGNHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVGRVRDRGITVPIVPGIMPIATYASFIRRANHMQCTVPPQWMDAL
EPVKNDDVAVREIGKTLVADMCRKLLANGISHLHFYTMNLAQATRMVLEELDWAPCAERP
LHHALPWKQSKALGRRDEDVRPIFWRNRSTSYVRRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEVNRKKWGAPTTVRDVANTFVRYLDLEIDSLPWSESPLTGEADMIKPDLVA
LNKRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPPEIVSEMIRRVEARP
SLSYYATTQDGDLMTNVTSEGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
AHCFDPGSPSRVLVERIMSEWYLVNIVDNDFRNNRAIFEVLNDLQVKDLDVPHAA
>A0A661KLD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTESRLEKVLEKGEFAVTSECGPPRGADPDLIRKKGELLKGVVDAVNVTDCQTSVVRMS
SLSCCLILKEMGFDPIVQMVTRDRNRIAIQSDILGAAALGINNILCLSGDHQRFGDHPQA
KNVYDIDSIQLIMTVKQMRDEGKFLSGEELTKVPRLFIGAAANPFADPFEIRALRLAKKV
AAGAQFIQTQCIYNLKRFEEWMHRVVDMGLHEKVCILAGVTPMKSVGMARYMKNMVPGMD
VPDEIIERLKGVPKEKQGEEGIKICIETIQRLREMEGVRGVHIMAIEWEEKVREIAEGAG
LLPRPRI
>A0A2G6FN02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTIKELFTHKKVFSFEVFPPKKNSSITTIYDTLAELSDLQPDFISVTYGAGGNAADNTTC
EIASFIKKRYNINSLAHLTCINSSKKDVDTVLESLKKEKITNILALRGDINPDIQRQGDF
HYASELVEYIKEKGDFSISGACYPEGHLESENAINDIHFLKQKVDAGVDHLISQLFFDNN
LFYSFIEKTRIAGITVPIQAGIMPVVNKKQIERMVSLCGVSLPAKFSKTMKRFEYNNEAL
RDAGIAYAVNQIIDLVANGVDGIHLYTMNNPYIARKIAGSIKNIIA
>A0A661IAT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
DHIDAMPVFDIDSVHLIQAVRTLEQGKDMAGNELDGPVSFCVGATVTPEADPLEPQLLKF
RKKVRAGIDFVQTQAVYDLDKFRRFMEFARKFDRVKILAGIVLLASVGMARYMNANVPGI
FVPEEMIRELASAPKGKAIEKGIEIAARLIRTIRDERICDGVHIMAIGREERVLDILDAA
GM
>A0A3S8ZW65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Iodobacter ciconiae|TrEMBL
MTPSPISFEFFPPRTPEGAEKLRTTRRQLAQFKPEFFSVTFGAGGTTQEGTLNAVLDIQS
EGHFAAPHLSCVGSSKESIRNIVQNYKDHGIRHIVALRGDIPSGMGDFGEFRYANELVSF
LRHEFGDWFHIEVAAYPEFHPQAQSAEADIHNFVNKVRAGADSAITQYFFNADAYFRFVD
EVNARGITIPIVPGIMPIQNFSQLARFSDMCGAEIPRWLRLRLQAFGDDTASIRAFGLDF
VTELSDRVLAGGAPGLHFYTLNAAGAVSTVCQRLGR
>A0A534V0Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSTLRERLESGQFVITTEIEPPKGTDLSQFLSTAALLKGKVDAINVTDNQRAIMRLSSVG
GATLLVREGLEPILQLTCRDRNRMALQSDLLTASVLGVRNVLAMTGDPVDAGDHPMAKAV
FDISSAALLELIGQLNLGHDGAGHPLEGKTDFFCGATVNPCVEPLEPELKRFEEKIAASA
RFFQTQAIYDLEAFARFIAIARKLPVYIIAGLIPLRSVRMAHFLNEKVPGIHVPTTMIER
LDRAADPIECGLAIAAELVEALRQLCQGIHLMIVGKEKDFAILERLPVKNEAKAV
>A0A661JJ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSNLEKILSKGIFAVTGELGPPRGADANAIREKAKHLKGMVDAVNITDNQTAVVRMS
SWAASIIAIHEGLEPNYQMVCRDRNRIAMQSDILGAYALGIRNMLCLSGDHQIFGDHPYS
KKVYDIDSMQLISMVKKMRDEGKFLNGEEISEPPRMFIGAAANPFADPCEFRVFRLAKKI
KAGADFIQTQCIYNMDRFREWIKEANDMGLTEKVYVLAGITPLKGLGMARYMKKNVPGID
VPDSIIKRLEGVQKKKQAAEGIKICCEQIEEFKEMKGVAGVHIMAIEWEHRVPEIVEQAQ
LLPRPNPQDLD
>A0A520RQB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|OM182 bacterium|TrEMBL
MALTQPKPATCLPPLSFEFFPPRDEESIDRLVSGTACRLGAYAPEFFSITYGADGSSKEG
TLRSVAALLEANRNTAPHLSQGSDTDTAIIELINRYLALGVTRLVALKGDARKAGDRRPV
YARDLVRTIRQHFGDALRISVAAYPEVHPDTASLDLEMKFFVEKVNAGADEAITQYFYNP
EAYANFLDHCARMGLDLPIVPGIMPITNYQGLMRFSERAGADIPRWLDRTLRDKSDNVAD
LCAFGDEVVTNLCERVIQMGAPRLHFYSLNRWGACSRICDNLGYVKT
>A0A2V3ZSV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinifilum breve|TrEMBL
MKVIEHLNQAIENKTTHFSFELLPPLRGNSIYKVFNTIEKLKEFDPKYINITAHRDEVVF
VESANGAFEKKITRKRPGTVAVAGAIQNKYKITVVPHVICSGFTPEETENALLDLNFLGI
HDLLLLQGDKSPRHDFIPSEGEHKYAIDLIGQVNDVNKGNFLDGTHVEPFETPFSYGTAG
YPEKHENAPNMESDLYWLKKKVDAGADYIVTQMFFDNQKFFDFEKRVREAGITVPIVPGI
KPISALSQLNVLPQIFKTEIPEALAAEVRKCKSNDEVKQVGVEWGIQQSKELIQHGVPSL
HFYTLMASSCVRDIAKAIY
>A0A534RNG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKIRQLYGRGGPVISFEFFPPATPAGEAALVRTIEALKPLGPGFVSVTRTGTKPREAPVE
LVVRIRALGIEAAAHVTCIEASREEIAAHCDLMVGRGIENVVAIRGDVPQDPAFRRPANG
FRHAVDMIRFMREGGHGFCLVGGGHPEGHPECRDLELNIEHLREKVDAGVDVVITQLFYD
NADYFAFVERARRVGIRVPLVPGIMPITNWPQIERITTLSGNQVPPRLHAALERVRNDEP
AAVAVGVEWATRQCVELLRGGAPGVHFYTLNKSPATRAIFENLRREGLLGH
>A0A341EZI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas koreensis|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETADHFHIEVAAYPEMHPQARNYEDDLANFVRKAKAGADSAITQYFFNADSYFY
FVDRLQALGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTRSIQSFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A1W9GP86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SG-bin1|TrEMBL
MSREPQRLIDVLNRGTFAVTVEYNPPKGTNISSVLENAKQLVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKD
AKPVYDLDSVQVMQLVQGLNNGKDMAGNKLDGPTAFTIGAAVTPEADLVGPVLAKFEVKV
KAGAQFFQTQAVYDPDVFAGFMKQARPFNVKVLAGILLLRNAKMAEFMNANIPGMSVPKD
MIDELKAAGEKAEDVGVDIAIRTIRAVRPHCDGVHIMAIKATHRLTEIITKAELD
>A0A852E6Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vidua macroura|TrEMBL
MVNETQHTCSGSSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A848XZS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermaceae bacterium|TrEMBL
MKVTEHYDRADGPLISYEIIPPRRGSSVEEILGIVESLMPYEPPFIDVTSHAAEAYYEEM
PDGSVRRHTKRKRPGTLGLCAAIQYRYGIDAVPHILCRGFTREETEDALIELHYLGIRNV
LAVRGDDLGYVKPERADRSRNAYAADLVAQVGDMNRGHFLEDLIDAAPTDFCIGVGGYPE
KHEEAPNMTWDVLNLKRKVDAGADYVVTQMFFDNRHYFDFVERCREVGITVPIVPGLKIL
TSKNHLRSLPRTFHAEIPEALAAEAEAAKDGQVAAIGVAWAQQQAEELMSAGVPGIHFYI
MSTAEHVLGVVEPLRKLA
>A0A257UNC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium 37-65-8|TrEMBL
MKKAPLIFDGAVGTVIYDRGVFINTCYDELCLTNPKLILQIHRDYVEAGAEVIETNTFGA
NPIRLKPYGLAEKTEAINRAGVRLAREAAGDEVFVAGSVGPCTESRQRMPDAFAAEVEAA
FRTQMGALAAEGVDLFLLETFSNLNELQLAARVGKEFAKPVLASFVLNDRGETALGMRAE
TMASALSADPNVDIVGINCGTGPSGAFDALQAILPHTGKPVVVMPNAGMPREISGRVMYL
TSPEYFTEYAKKYIELGVRGVGGCCGTTPAHIRMAARAVKPLRIGKRRVEVKPLLRQESL
VYAVPTERKSRLAAKMCAGEKVTSVELVPPKSSDMTALLDRARKCAEAGVDAINIPDGPR
ASARVSPMISALTILQQVGIEPILHYCCRDRNLIGMQSDLLGGYAAKLANFLIITGDPPK
LGEYPDVTGVFDVDSIGLVQVAANLNRGLDIGGNPIDPPTGLFIGVGANPCAVDLEREIE
RYFRKIDAGAEFAITQPVFDPDALLRFLDRAETHRRKIPVLAGVWPLVSFKNAEFMNNEV
PGVVVPKAILERMSRCRTREDGRKAGIEIARGIVERISDRVNGFQVSAPMGHVETALAVL
EK
>A0A645D3R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MAETGEFRYANELVEFIRAETGGQFSIEVAAYPEWHPQARSPQDDLQNFARKVKAGANSA
ITQYFYNADAYFHFVDEARALGVDIPIIPGIMPIVGFTKLARFSDACGADLPRWMRKKFE
SYGDDSESIRAFGLDLVTELCARLLQGGAPGLHFYSMNQAPLTLEICRRLGN
>A0A4Z0DN50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYSPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWIGRKMQAYGDDTESVRAFGAEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQG
>A0A139NXS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQRDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A4Q0HIC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromohalobacter salexigens|TrEMBL
MSTREHPLGVSFEFFPPNTEAGREKLKGVRDTLAERRPRFFSVTYGAGGSTQARTFETVQ
TVRQSGIDTAPHLSCIGSDKGELRERLASFREAGIDSLVALRGDLPSGMGGMGELRYANE
LVEFIREETGDHFQIAVAAYPEAHPQAPSYEHDLQNFVRKMQSGADLAITQYFFSADAYF
HFVERARALGVEAPIVPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIQAF
GSEVVTRLCQRLLDGGAPGLHFYTLNQATPALRVLDNLRCDT
>A0A139QYY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFCYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A328YLZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium aciduliphilum|TrEMBL
MKVTQHIENANGKPLFSFEILPPLKGQNIQFIYDGIDPLMEFNPPFIDVTYHREEYEYKE
LPNGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKTETYFHPEKEGNAYASELVTQISNLNKGIYLDEDLKNTAKTNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNKKFFEFVDKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMEVVKAKDNDEVKQIGIEWCIAQSKELVKAGIPVLH
YYSMGKAANIKAIAKEVF
>A0A1Q7ZYN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_1_20CM_2_66_18|TrEMBL
MLRAPRYEVLPTDNAAELVAAYVPREVTITVTASPRRGMPRTIHLAVALAKLGYHAVPHL
SARLIHDRVELGQILVALKDAGIKNVFVVAGDAREPAGLFPDALSLLAALPPDHGLTEIG
VTGYPESHPFIHDDMTIQAMWDKRRLATYIVSNMSFDPDGVKRWVGRVRNRGVELPIYIG
MAGVADPARLMRLSTKIGLADSARFLRGHPSWVARMFRPGGYEPGRFVNALLPDVAMPER
RIAGLHVFTFNEIEPTERWRREMLAEIR
>A0A503AR76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-7-1|TrEMBL
MTGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLGHILHDEITETQVDMVK
TAH
>A0A258XBF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. 16-46-70|TrEMBL
MELSVEFFPPKTPEGESKLHVVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
TETGDWFHIDVAAYPETHPQAKSPATDVDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YDLGVTQPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDTASIRAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLSLNK
>A0A2P4THQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bambusicola thoracicus|TrEMBL
IVYGTKGQHEMKDHQRDGRRHQNEGIRHTKLRALTMVNENQHTCSASSSSKSDGGSSSGS
ESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDRWFSLEFFPPRTANAAVNLISRFDRM
AAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDITGHLQ
KAKRLGLKNIMALRGDPVGEEWEEEVHGFNHAVDLVKHIRSEFDDYFDICVAGYPKGHPE
AESYEADLKHLKEKVLAGADFIITQLFFRPETFLKFMKDCQAIGITCPIIPGIFPIQGYH
SLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTL
NREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDD
FPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVFTCYITGEP
NKNGHRVTCMPWNDDPLATETSLLKEQLEKVNRRGILTINSQPNINGKPSTDPIFGWGPS
GGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGI
FPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVD
NDFPLENCLWQVVDDTFELLNSPPQQ
>A0A2J6ICE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinilabiliales bacterium|TrEMBL
MHKTVIQHIESSEGTLFSFELLPPLKGQDFGAIQRSIDPLMEFKPSFINITYHQEEVEYE
TLENGLMKKNVVRKRPGSVGISAAIKFRYGVNVVPHIICGGFTREDTENALIDLNFLGVN
NVLVVRGDPQPGMKTFIPEPNGNKYAIDTVIQIANLNKGIYLDENIRNSRSTNFCVGIAG
YPEKHSEAPNMESGIHFLKKKIEAGASYIVTQMFFDNKKYFDFVKLCRENGIDVPIIPGL
KPISTRNQIAIIPKTFNVELPEDLVKEVLKCKNNDDVRALGVEWAIAQSKELKDAGVPVL
HYYTMGKSDNIRKIALDVF
>A0A1Q8L6N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. Ae706_Ps2|TrEMBL
MPRPGQFRPQGLYPRTVTDGFRIICEIEPPTRPDLTHARHQIGVLTPVSDAFLIPDNHIG
RATVSSIAVANEVRAMGGAGIACVNSRDRNLLGFRRDLLTAAAYGVDQFLFVQGDKPSVG
DRTGELTVRTMIEEARAATGQDAFAGVAPFRLGVTAGHRRRMAAWKQAADFVFVQVGYSA
EAFLQWREANPMDLPVYAGVMVLASAGMATRLRASIPDIDIPDELVHRVSDDPAAGVDAA
CEQIRALRDTGAFAGVHLVPVSRFREVAARLERERR
>A0A139RN18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MGNDKIISALQDMQELAPHFISVTASNNKFSIKETTVRLADFIQNDLEIPTIAHLPAIYL
TKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATDLIAFIKEQAPHFDVIGAC
YPEGHPDSANQISDIQFLKKKVDAGCSSLVTQLFFDNERFYDFQDKCTLAGIDVPIHAGI
MPILNRNQALRLLKTCENIYLPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVA
GVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A644W7J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MIVSSLLRETKSTLFSFELLPPLKGDHISAIYDTIDPLMEFKPSYINVTYHREELVYKQR
TDGLLEPRRVRKRPGTVGITAAIMHKYKVEVVPHMICAGFNREETENALIDLHFLGVNNI
LVLRGDAEKSARRFIPEPDGHEHATGLLRQVMQMNKGKYLDEDMEYQTPTNFSVGVAGYP
EKHAEAPNPDNDLHWLKEKIACGAEYIVTQMFFDNRRYFDFVKRCREAGITVPIIPGLKP
VSVKNHLNILPDTFHVDIPEELAREVVAANDNQTVRRIGVDWAVEQVRGLKAAGVPSIHF
YTMGKSDNIREIVSRGF
>A0A2N5Z3E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinilabiliales bacterium|TrEMBL
MKVIERLNQAEKPLFTFELLPPPKGADITKLYDSIGKLIEFNPAYVNITYHQQEEVFKKR
PDGLLEKQIVRKRPGTVAISAAIKYKYGVDVVPHIICGGFTKEETENALIDLNFLGIKNL
LVLRGDPPKNQRYFTPETGGHQYAIDLLKQIVNLNEGRYLDETIQNSSATDFCVGVAGYP
EKHIEAPNMKTDLQHLKEKVDAGADYVVTQMFFDNQKYFDFVENCRNIGIEVPIIPGMKP
ITTLSDVKLLPKVFSIDIPEDLSCELDKCKTNEDAWQVGIEWSVKQSKQLVEFGVPSLHY
YTIGRADNIREIAKNIF
>A0A7W3GHC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. RHBSTW-00271|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A365K453|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus maitriensis|TrEMBL
MLLDELKKRMLTADGAMGTLLYSYGIEYCNEELNIQRPEVIEKIHRDYIAAGADIIQTNT
YGANAHKLARYGLEEQTEAINKAAIAIANKAAKDGGQFVVGTIGGIRGIRKSDATLDEIV
AMVDQQAQHLLSGDPDGLLLETYYDFEELAATVSHLKKLTDAPLIAQLSMHEPGILQNGM
SLNEGLKRLDALGAEIVGVNCRLGPHHTIQAFEGVELPEKAFLSAYPNASLLDIEDGRIV
YESEADYFGRAALLLREEGVRLIGGCCGTTPKHIEAVKKRIGHLQPITEKKVEEKKPIVI
REAEALKDKPLHEKAKTERTIIVELDTPRHLDVEKFLEGSKALDAEGIDAITMADNSLAS
PRISNMAMGSILKHKQDVRPLAHITCRDRNLIGLQSHIMGLNALGIHDILAVTGDPTKVG
DFPGATSVYDVSSLELIQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVVERAVQRL
EKKIEAGADYFISQPVYTKEKIIEIHEATKHLDTPIFLGVMPLTSIRSADFLHNEVPGIK
LSEEALDRMRACGEDKDKATAEGIQIAKELIDTAAELFNGIYLITPFVRYDMTVELIRHI
RQLDLKKASDRAYA
>A0A7X9BDR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MKYLSKLQAVLEEGHFAVTTEIGPPKNASPQSLINKALLLKGFVDAANITDNQTAVVRLS
SIASGVHLANSGLEPVIQMTCRDRNRIAIQGDLLGAYSMGMRNLLCLSGDHQQFGNHPTA
KGVYDVDSIQLISLMTRMRDEKKFFCGEEIKGDEPGFYIGAVANPFADPFEFRVDRLEKK
IDAGAQFIQTQGIFDMERFERFMELVRARGLDRRAHILAGVIPLKSPRAAKFMQTQVAGM
IVPEDLVERLQKAADPKSEGVAICVEQIKYIRENIKGVHGIHIMAIAWEDIVPGIVEQAG
LFPRPAVQLD
>A0A231W8L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. OG2|TrEMBL
MSLLDKMEKEIIIADGAMGTLLYSYGTDFCFEELNVSQPGHIQNIHQAYIDAGATLIQTN
TYAANYLKLQRYGLEDHVKEINSAAVTVARKAAGNHAFVAGTIGGNRGIKPHSISIEEIK
RSFREQLYCLLMEGVDAILLETYYDLKELETVLSIARKETALPLIAQVSLQETGIMQDHT
PISEALSRLDALGADIVGLNCRLGPHHMLLTLEEVPLPQKAYLSAYPNASLPAYTDGKFH
YEGDAEYFRQSAKAFRNQGVRLLGGCCGTTPAHIRAFSDELKGSPPLEKKEVREPKAKIR
IMPKEAQRDLPPLQDLVKKRQSVIVELDPPRKLETDKFFAGAKALQDAGIDAITLADNSL
ASPRISNEALGYLAKNRLGLRPLIHLTCRDRNIIGLQSHLMGLHTLGLHDILAITGDPAR
VGDFPGASSVYDMSSFELIQMIKQLNEGRSISGKDLGQKAAFSVAAAFNPNVRSLEKAVQ
RLEKKAECGADYFITQPVFSEEKLMEIYEATKHMEQPIYIGLMPLTSSRNADFLHNEVPG
IKISDKIRERMNSLKDDPLQSVREGISISKELIDAAAELFNGIYLITPFMKYELTAELAA
YARSEKLKTARRSRNAKDFSI
>A0A1I5XEI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. 770b2|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYVRKPQFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATKATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFHYASDLVAFI
REETGSDFHIEVACYPEIHPQARSPEADMQAFAAKVKAGADSAITQYFFSAEAYFRFVDD
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLCDGGAPAIHFYTMNQSAATLAVLERLD
>T0TIL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris TIFN6|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPTVAHLPAAYLDKTQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>L7IP25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnaporthe oryzae (strain Y34)|TrEMBL
MDKITDKIAALPPDASYFSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
AQKSLELAEICQRELALTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRPGE
YAIPDDSEGDVNEFTWAIDLVRYIKLNHGDYFCVGVAAYPEGHAEESHPTNQSLEHDLPY
LVEKTQAGADFIITQLFFDISAYEKFEKTLREHPSGAFKDIPIIPGLMPIQNYQMIKRTT
KLSHAKIPDPLMARLDAVKKDDEQVKKVGVDIISELVDQVKEVKNRSSGPKGFHFYTLNL
EKAVSFIVERTNLIPATTPDDDEVAVVDDVALPSIHLNGATPAKDHLSVSSLHPPTHTNS
RRPSTIGSDPRNRVIVSSGRPASHPDYEATGFEASVPAQAINSRANTLAISEGEGVLGRE
ATWDDYPNGRWGDARSPAYGEIDGYGVSLHMSGTQAVQLWGRPATVEDVSNIFMRHLRGA
LPAIPWSEEEFNAETETIRDTLLALNSRGWWTVASQPAVNGLRSNDRTFGWGPQNGFVFQ
KAFVEMFLPSKDWKALREKLLSEKDVVCFYASNAKGDFESSDGGGDAPDGAPTGNGFADE
QPLPSGSSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWAEWAKVYGKDSPSEKL
LESLRADLWLVNIIHHDYIEKEALWDLLLK
>A0A481Q9H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia hibernica|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWNSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKDIKERTGLEAAPHLTCIDASPTQLRDIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDDDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A3L9L0D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria tytonicola|TrEMBL
MPAPLAAARTAPVHPVEPPTGTSWLVRRPRRSTLVSFEVFPPRPTADPNTVWRSIDAMAQ
AGPDFFSVTHGHSGAPGVTREALRHLRRTTNTPVMAHFTCGGTDRAGLESAVEQLLDDGV
RDLLALRGDPPLGGAEWVTPPGGLNRASDLVRLVRDVERRRFGDGFRPGTRPLSVSVACY
PSPARGRDFEADLASLWDKQEAGADYGITQVLYEPEDYARFLERARSEGIHIPVVAGLMP
LTDPRRLRRMTEITGVSVPRRLTDFLAADSPEDMRHRGIAATLSLIDDLLDLGCAGFHLY
TFNRPEAALTILEHLRVRDAAREYRGRSPAV
>A9DJE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kordia algicida OT-1|TrEMBL
MKVTDHIAKSEGKTLFSFEILPPLKGQDIKSIFDNIDPLMDYKPPFIDVTYHREEYTFKE
LDNGLLKKQVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKAEKDGHRYASELVSQIQDLNNGKYLDEELQNSSKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKAGAEYIVTQMFFDNQKYFEFVEKCRSEGITVPIIPGLK
PIATRKQLNLIPHRFKVDLPDDLIMAVVRCKDNKAVRQVGIEWCTQQSKELVAAGVPILH
YYSMGRSSNINAIAKEVF
>A0A1I8AXB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steinernema glaseri|TrEMBL
XNPDFFSCTYGAGGSTRDRTLNTVLQLESEVKVPAAPHLSCVGDSKDDLRSLLAQYKAAG
IKRIVALRGDLPSGMGMASGELRYANELVEFIRQESGDHFHIEVAAYPEMHPQARHFEDD
LINFVRKAKAGAD
>A0A7D4JJ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella melaninogenica|TrEMBL
MGNNITDIKQLLNDETDEKHFSFEVLPPLKGNGTASLFRNIDQLKEFNPSFINITTHHSE
FVYHEREDGLLERQRIRRRPGTVAIAAAIQQRYGIPVIPHVICSGATKEDIEYELLDLQF
LGIKNLMLLRGDKAREDRFFTPTEGGHSHTTELIEQVNSFNEGVFIDGSTMKHPGRPFVY
GVACYPEKHEEAPNLEQDLRYLKMKQDLGATFAVTQLFYDNEKFYNFVDQARKIGVTIPI
IPGIKPFAKLSQLNVVPKTFHCDIPEELAGLALLCKSDEEARLLGIEWAVRQVKDLYAHG
FNNVHFYTVSAVSSVHEVMKRLVETGLLQQNSK
>A0A849MSD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobi bacterium|TrEMBL
MIFNKRGSRPFITDGSMAVELAKRGFAERPPDRYNLSSPTVVERIYHDFIQAGATLLQTN
TLFSNRFALESVMLSARVAELNRKGVWLARTASAGRVPVLGVIGPTGRLLQPLGPLNATD
AVECFREQAASLLSAGCDAIALKSFIDITELEIAISAVRAVSTDVDVIALKSFPEDAAVL
SGPYPKLFAKRITRLGIQAFGSNGTVGPQRMVGIIDALANDTIPLVAIPDVGIPTMIGGT
AVYHADPEYVGQAATRLAEHGASIVGADGGATVEHIAAIAQAVASASVGSKTPVAQVTEH
NAVPDSHPKPPTQWYTDLQSKFVRTVELDIPRGLDMSSVIEGARYLHTNGIDAVNISDGA
RARLRMNPISISRLVMDAVGIQCITHMACRDRNMVGLQSDLLGAHELDVRNILAVTGDPT
HIGDFPYASSVYDVDSIGMIRAMDRMNHGNDLMGNPLGSATSFSIACAVNPAADDIEREV
DRLAQKAEQGAIAAFSQPVFDDDALYTFLERISNIPIKFIVGIIPLRNLRHAEFLHFEVP
GMHIPSWVRKHMLENNESQQQATSAGIHLAVQMLSAVKNKVHGVYLMPPFKKYSVAVEVL
QRAGL
>A0A6G2ILB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HUCO-GS316|TrEMBL
MTLRETLASGTRSFSFEFFPPRTQAGHRAVWDAIRRIEPLAPAFVSVTYGAGGSSRDRTV
ELTQRIASDTTLRPVAHLTAVGHSVGELRRIIGQYADAGVRDVLVLRGDPPGDPQGPWVP
HPDGFTYAHELVTLVREAGAFSVGVAAFPERHPRSADWDSEIRHFVAKCRAGADYAVTQM
FFDVEDYLRLRDRVAAAGCDIPIIPEIMPATDVRQIRRFAELSNAAFPVELARRLDAARD
RPAEGHRIGVEYAVAMTERLLAEGAPGLHYITLNRSTATLDIHRAVMAAQAVTA
>A0A6N2ELN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp. PLM2.Bin73|TrEMBL
MLLQQALASGRTAITAEVTPPRGGDPSRTLAAARQLQGWVHAVNVTDGSRAVMRMSSLAV
CRLLQEEGLEPVLQMACRDRNRIALQADLLGAHALGLRNLLCLTGDPVRAGDQPAARAVN
ELESVRLLQLVDQLNQGADPVDGRLPDGGTAFFAGAAADPQCPSWSGLRARVRRKREAGA
RFLQTQMVTDADALRRFVEEIAAPLGLPVLAGVFLLKSARNAAFINRVVPGANIPQGVID
RLAAAPDPASEGILIASEQVASYVTIAQGVHLMAIKAEERIPLILERAGLRAEATQLDPA
PLLSSPG
>A0A443TDR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLELLSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINRAAVKLAKASVTEKNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGTLLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIAGMKRAIANITPVIAKETIQRPKVVH
THEKRSRVHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHEIKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A4R1F3K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cocleimonas flava|TrEMBL
MKFSDEPIPGENLSILPGHSSFGRLERILRAGHFTVTSEMAPPDSADPQEVYKQAALFDG
VTDAINATDGSGANCHMSSVGVCSLLTRKGYSMVMQISCRDKNRIAIQGDVLGASAMGVA
NMLCLTGDGVQAGDHPEAKPVFDLDAMTLLQTIKIMRDEKRFLSGRKLDTPPHSFLGAAA
NPFAEPREFRVDRLAKKIEAGAQFIQTQYCFDIPVFKEYMARAGDKGLLDKVFILAGVGP
MASARSATWIRDNVPGIHIPDWVIKRLKDAENPKQEGQQICIELMQQLKEIEGVAGVHVM
AYRQESSVKDIVLKSGVLGDRIPWHPDQAE
>A0A1F5C5C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium RBG_16_35_8|TrEMBL
MIHHIQNKIYHVEVLPPKQDSEKLEKDLEIFSNKYFRVMNNGYCACITDNTMGLLSFQGT
EMIEELELSVIPEQVMIHLNTFHTKDDLDNILDICKSKGIKYLLIITGDGSERLPKLRPS
DVGATDVESVTSVELLKYINREYPDTFVLGVAFNPYEPEEHEFEKMERKIKAGATFIITQ
PLIERNEVVDRLLEKYPGIPVIVEAWMSKKLHLLSEAVGYEIPENKEFDPISTLKMLHKL
YPGCGVYLALLGFKTQYDLIKDTWV
>A0A0N0UT52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus apinorum|TrEMBL
MRDQTFSVEIEANSHDLIQMKHYINKWKPDFVSISNLSRYSYEEMIKCAQYIQRDLNIPV
ILHLTGLSHTKEEIKKAFTEFRESDIKNLLLVRGNLHHNMEVQDDFSYASDLIEYVNQLD
KNDTTNIVAACYPDVHSFADSLKDDVFYLKKKVDSGVNSLISLMCFDNHKIYDFLKEAHK
KSINIPIRIGIMPITDPFKKHYLLHNEIDVPEFVDESTDMLDDGIEFAVEQIDDLYEHHV
DGIHLYTQNDWEVSDRIYEEIKHNFE
>A0A1H5BQE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TLI_105|TrEMBL
MALGTASVRSDRARTVREILAAGDTSYSFEFYAPRTEKGEQVLWNAMRRVEAVGPSFVSV
TYGAGGSTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNILGQYADAGIRNMLALR
GDPAGDPLGEWIEHPEGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVAKAGCETPIIPEVMPVVNVKTLDRLPQLSNAAF
PADVKERILAVKDDPTAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A417H591|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM28-41|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A2H6GJR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Abin14|TrEMBL
MKISEILSRNRPALSFEFFPPRNPESEHVLDETVGKLRRFNPDFVSVTYGAGGSTREKSL
YWTTGIREKYGLNVMMHLTCIASSRRDIQDICRRLRMEGISNILALRGDPSRDLPDYRIQ
KDFRFAYELVEYLRETDDFSIGVAGYPEGHLDAVSLGRDIENLKRKVDAGADFIITQLFF
DNRHFFDFMDRVAAAHIEIPVIPGIMPITNAGQVQRFTEMCGATVPGEIKGRIDNTEDVF
RVGVDYAIEQCKELLDFGVPGLHFYTLNRNRATEEILAGIGKVLERE
>A0A3A5EG49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. CFBP 7698|TrEMBL
MHPATPRPASTLTDAYSLEVGAHDIAALSAVAPRIVPGTLIAIPSLPGQDDATRLAAAQR
VRGLGFAPMPHLSARRIASLDALQAFVGRAVDDAGVAHCLVVAGDPSLPLGPYPDSLALI
ATGVFERAGIKTIAVAGHPEGHPAMHADDRWAVLQRKCRSIAERGMAPLIVSQFAFDADL
VLTWLNALRAHGIEAPVRVGVPGPAGVAVLARYAARCGVGASAAMLSKYGISLGKLLGTA
GPDHFVDRLAAGLTPAHGDVRLHMFPFGGIARSLAWAEHYRSRTALAAATDLPTT
>A0A4R3N0P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobaca trueperi|TrEMBL
MSFPPVSNPLYSVELFPPKTPEGMDKLKLEIARLNALGPAYFSVTYGAGGSTREGTFETV
AWLRGLGIETAPHLACIGSSRDEVREILNQYLGQGIRRLVALRGDMPSGMGAGNSGDFRY
ANDLVSFVRAEFGDAFQIEVAAYPEYHPQSGSPARDLENFKRKVEAGADGAITQYFYNAD
AYFAFVESCRKEGIEVPIIPGIMPITNYTQLARFSDTCGAEIPRWVRRRLEGYGDDVESI
RAFGHEVVQRLCRELLAGGAPGLHFYTMNQSGPVQALWRELGLSD
>A0A4R4S3I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. KC207|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLVVR
GDPPGDPGGEWVRHPEGVLYAEDLVRLVRDCGDFSIGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAEGCDTPILAGVMPVTQLSTIERAVQLSGAPF
PPALAARFAEVADDPEAVRRLGIEQAAEMCRRLLDEGVPGIHFITLNRSTATREVWQQLQ
VSARV
>A0A1G1EVW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium GWB2_47_37|TrEMBL
MSFKDILNSGKFVVTAEVGPPKGTDIKEMIHHIELLKGKVDALNVTDNQSAVMRICSMAV
CRICLDHGVEPILQMTCRDRNRIGLQSDLLGASILNIKNVLCMTGDHVLAGDHKQAKPVY
DLESVQLLGVVNSLNNGKDMSGNEMKGSTDFFQGAVVTPEANPLEPQLIKFEKKVRAGAR
FFQTQAIYDINKFKEFMQYARKFPVKVLAGIVVLKSAGMANFINNNVPGIRVPIELIDEL
KAAGKEKALDTGLNIAARHIKQLKEENICDGVHIMAIGMEDKVPVIMERAGLL
>A0A1N6P4R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. TND4EL3|TrEMBL
MATHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRASIRAVLADFKAAGVNRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLQAFARKVQAGANAAITQYFYNADAYFQFVE
QTQKLGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A7Y5DTW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloglobulus sp|TrEMBL
MQSQQKYPKLFSFEFYPPKTEEGAASLQVVHSKLAALNPDFFSVTFGAGGSTRDKTFDTV
VDI
>K0C9N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cycloclasticus sp. (strain P1)|TrEMBL
MSLESYQKISFEFFPPKTEEGRVKLLNVSKELGQLDPAYFSVTFGAGGSTQQGTIDTVLD
IKKQGFSAAPHLSCVGSTKASIRKILSNYKDNGVDRIVALRGDIPSGTLDIGEFRYANEL
VAFIREETGDHFHIEVAAYPEVHPQAANAQADLANFKQKVEAGADSAITQYFFNFEAYVR
FVEDCDKMAINVPIVPGIMPIINYSQLARFSDMCGAEIPRWIRKRLEGFADDRESIKAFG
TDVVSELSQTLLDYGCPGLHFYSMNQAEASLAICRNLGISAK
>A0A6I3P1F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKDLFAHQPNFEVN
>A0A0J8RJS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccidioides immitis H538.4|TrEMBL
MHVKEKLAHSEASGRPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPPREKES
WAPTEGGFRYAKDLVKYIREKYGNHFDIGVAGYPEGCEDEEDPETLMKHLKEKVDAGGTF
IITQMFYDVDIFLDWVKRCRENGIQVPILPGIMPISTYASFLRRSNWVKCKVPESWMEAL
EPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHL
>A0A5J5L484|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula sp. CBA1129|TrEMBL
MALGTRAVADSQGVRTLLTSARFELMPFESFDEEITHLPDNATIAITTSPQLGIEKTVEK
TEEAAEMGYDVVPHIAARYVEDREQLEEIAERLAQAGITDIFVPGGDREEPAGEYESALD
LLEALAETEYAFEEVGITGYPEGHDFIDDETLAESMAQKAPHATYIVTQLCYDPDTVLEW
VGDIRARGVDLPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDDEYNIRGIHIYTFNQTPDTEQWRRNRLDT
>A0A840PES8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermocatellispora tengchongensis|TrEMBL
MPSHSPAGAIGRRRALGQALHAISYEVLPFRNTEESVLAHVPRTVPLTITTTEAKGLAPT
IDLAVRLTGHGYSAAPHLAARLVRDKQQLTDIVARLREAGVEEVFVIGGDAPEPAGAFPD
ALSLLEALHAAGHHFRRIGIGGYPEGHGSIGRELIDRAIEQKSRYATHVITQLCFDAATT
IAWAGRLRERGVDLPVRVGLPGAVTRQKLIRISAGLGLGQSARFLNKQQNLLWRFFLPGG
YSPNRLVERLAPHVAEPGGPLAGFHFFTFNELDKTESWRRRMLERAR
>A0A094GHU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4519|TrEMBL
MADSPTTDKITDKIAALPQDASYFSLEFFPPKTAMGSTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSKALVDDALKAAKEAGIQNILALRGD
EPRGEYKDALEEGKEGEDEFVWAIDLVKYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
EHDLPYLVDKVQAGADFIMTQLFYDVDAYDNFEKVLRDHSSGAFKSIPIIPGLMPIQSYQ
ILRRTTKLSNAKLPESIIDRLDAVRTDDEMVKKVGVDILAEIVESVKATKQRTKGPKGFH
FYTLNLEKAVAFILERVNLIPSFTPVLTSDAFAVDDITDTIPLPQLLINGERKNRRQSSV
GSGPHNFVIIDREEASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRPDITSIFVQYLNGTLSALPWSDE
PIAAEANLIKNELVKLNQKGWWTIASQPAVNGARSQDGVVGWGPKGGWVFQKAFVELFVP
TSDWARLKPLLEGNGEVSFLAQSASGEFLKSKLDLGPGEEGTETNAVTWGVFPGKEIVSP
TIVEEVSFRAWAEEAWQMWEEWAAVFGKSGEESRRFLDGVAKDGWLVNVIWHDFVGMCKA
KEGRSEEEGYKGLWDVLIEA
>A0A4Q4UXH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus sp. MC13-8B|TrEMBL
MEKITDKIAALPADSNYFSLEFFPPKTTMGFANLRDRLDRMARALRPLFVNVTWGAGGST
ATKSLELAEICQRELSLTTCLHLTCTNMSRRMIDAALEDAKALGIRNILALRGDPPRAAE
YQDPNGEPEDAIDEDFKWAIDLVRYIRKTHGDYFCIGVAAYPEGHADESHPQGQSLEHDL
PYLVEKTLAGADFIMTQLFFDTEAYDRFERILREHPSGAFKTLPIIPGLMPIQSYQMIKR
TTKLSHAKIPDPISARLDAVKKDDEKVKNVGVDILSEIVERVKEIKSRTPGPKGFHFYTL
NLEKAVSFILERTKLIPPSTPEEDEAVADVLASRAPTVEVNGSTHEPSMPTKHRERRESI
ARSDVDASIHELPVPAQERIRRQSTVGSEPRNRVIVSEGSPSHPEYEATQAEASILAEPI
NTRANTLAISEGEGTLGREATWDDFPNGRWGDARSPAYGEIDGYGPSLHVTNAQAITLWG
YPKKPEDINGLFVRHLKGELSAIPWSEEELNAETATIADQLLALNSKGWWTVASQPAVNG
LPSSDPTFGWGPQQGFIFQKAFVEFFLPSAEWRVLAEKLQSAEVQDTVSWYAASATGDFA
SSDLTGGLAGEAAKEPSTNAVTWGVFPGKEIVTPTIIEEVSFRAWADEAFGIFAEWAKVY
GKGSESAALLEAVRADVWLVNIIHHDYVDTDALWNLLLH
>A0A2K2HEK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geothermobacter hydrogeniphilus|TrEMBL
MGDLAIELVPRSREVLERDLQTVREHFPRVRTINIPDLLQFPLRAWDAAEAIAPQVERVI
PHLRAIDFDLKEDWPFLDTIRRSGCPAVLAISGDPPQDMLHRTFRTPVTEFITRLKQELP
GVKVYAGLDPYRSGVKEELDYVRAKLNAGADGLFTQPFFDLRFMEIWADLLIGLDIWWGI
APVLTEKSQAYWENKNNGFFPPDFEPTLEWNRQFTKRALHFVKARGASAYIMPIRADIKK
YLDGII
>A0A559M9P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnellula willkommii|TrEMBL
MHVSQMLSEAERSKQPKFSFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLA
QLTCEMVSVAQSQYGLETCMHLTCTDMGKEKVNEALKATYKAGCTNILALRGDPPRENEK
WEATEGGFQYAKDLVKHIRDTYGNHFDIGVAGYPEGCDDQDDLELLLDHLKEKVDAGATF
IVTQMFYDVDNFLDWVRKVRAKGITIPIVPGIMPINTYASFLRRCNHMNCSIPPKWLEAL
EEVKNDDAAVRNIGTGLVGEMCRKILDSGLIHHLHFYTMNLAQATRMVLEDLKLTPSDER
PLKQALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQEWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEQNRKLWGEPTSIEDIAEIFVKYIENGVDSLPWSEAPITSEANSIKADLI
GLNKRGFLTINSQPAVDGVKSSNPVYGWGPANGYVYQKAYLELLVSPQSMDELIQRIERD
PDLTYYAVNKAGELKTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMD
WAHCYSNLSPSRNLIQNMMENWFLINIVHNDFHQTHGLFRLFDELSVSSIDKPFEVEYKN
GIETNGVNGSKPEHSENISLTNGA
>A0A3G6PP93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. G0186|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIEN
VMALRGDAMKGHQYFEPTQGGHASAMDLVDQINNLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A420DNT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter guttiformis|TrEMBL
MTTPAVSFEVFPPKTVDAAFKLWDTAQALAPLAPRFFSVTYGAGGTTRDLTKDAAHVLRR
TSGLPVSAHLTCVGASVAETLAEAEKFHAAGVTEIVALRGDPQNDETTFTPHPEGFKNSV
ELIEALALLDKFTIRVGAYPDCHPDATSQHANIQYLKRKFDAGAHEAITQFFFEPEQFLR
FRDQCAAAGIDKPIVPGILPVTNWASARKFAIRCGTKIPAWLDEAYRAAERDGRTELLST
SLCSELCSDLVDEGVDSLHFYTLNRPDLTRTVCRALGVTPQSALSNVA
>A0A7W5PRP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK275|TrEMBL
MALLNFTGKSREDNPEPEFADMIEDWTIEVIPRTAAKIDDFRALLPTGTRVYIAHIDGTP
IEDMVATARRLNAQGFPVMPHIPARSVPDRRTLADWLERYRSEADVRQALLLGGGRVRPI
GDFHSSMQLIETGLFDHHGFTDLHFAGHPEGSRDVDPDGSTALADRALLWKQDFASRTNA
KLALTTQFTFDAQPVIDWAERIQEAGVTMPIHVGIAGPAKLQTLLKYAISCGIGPSMKVL
QKRAMDITKLLLPYEPTELIAALADHKTRRPGSLISQLHIFPLGGIQVATDWMNKHRSVE
TPIALP
>A0A269ZHC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei|TrEMBL
MSASALRSLLTSARYEILPTSGIIDRITDHVAPGRTITVTASTGLGLDATLSTAEQLQAL
GYDAVPHIAARMVQGRTELTEIIDRIGHAGIDTIFVPAGDATPPAGGYASALDLLVDLTS
MAPPISRIGVSAYPESHPLIPDDVTVQAMWDKRDYATHIVSNLCFDPGVVSTWLARVRAR
GIELPLILGIPGKVELAKLAKVAAKIGVGESTRFLRKNTGTFTRMARPGGYNPRKFLDRL
SPVLADPYMDVSGLHIYTFNQVKDTEAWRRKQLELLGDPDSSSFVS
>R7UHV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capitella teleta|TrEMBL
MPEVLAQCQEKRKASDQNNQSSEEEGTDHGLLPIYKYRRLIDRINDRVQAGSKFFSLEFF
PPRTANGAVNLISRFDRMAMGRPLFCDITWHPAGDPGSDKPTSSTSIANSMVNYCGLETM
LHITCCGLTKQQITNHLTKAKNLGIRNILALRGDPPGDEEWKAPEDGFNFGTDLVRHIRE
VFGDHFVIAVAGYPTGHPDSPSYEEDLQHMKEKVDAGADFIITQLFFKAETFLKYVSDCR
AIGISVPIMPGILPIQAYQSLRHIVKLSRLEVPDDIIDTITPIKDNDEAIRNYGIFQATE
MCRDLLDSGSIHGLHFYTLNREVATIQVLKALGMWCEDPRRSLPWKTTANHNRCKEDVRP
IFWSARPQSYVYRTSEWDEFPNGRWGNSASAAFRDLSDYYLFYLKSRAPKEELLKMWGEE
LKCEKDVFGVFERYLTGEANPNGVKVNRIPWNDEPLASETTVIASELAELNRQGVLTINS
QPNVNGAPSTDPVHGWGNPGGFIYKKAYVEFFTAKENVECLLEVLKEYPQVDYHILDRKG
DADLTSTDLVQPAALTWGVFPGKEIIQPTVVDPIAFKSWRDEAFGLWREQWASLYDAASP
SRQIIQNIVDNYYLVNLVDNDFPRKTCLFELLNKMLEMRSNGGPTFAAAVEAQQ
>A0A7Z9QHX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiaceae bacterium|TrEMBL
MTNADRTYSFEFFPPKTDKGVDNLKATRAKLAKLKPEYFSCTFGAGGSTRDRTFETVVDI
QEETSIDAAPHLSCIDSTRDNIAGMLQGYRDKGIQRLVALRGDIPSGTVVVGEFRYANEL
VSYIRETTGDHFHIEVAAYPEIHPQANSARDDLINFKRKIDAGANSAITQYFYNADAYFR
FVDGCRDQGVDIPIIPGIMPITNYVQLARFSEMCGAEIPRWLRKRLADFGDDMDSLKAFG
IDVVTEMCRQLLDGGAPGLHFYTLNQASASIKIWDNLSLSD
>A0A838GV09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euzebyales bacterium|TrEMBL
MTTIRELLATGRPSFSFEFFPPKTDDGEAVLWQAVRELEPLAPTFVSVTYGAGGSTRDRT
VRIVRRIATETTLEPVAHLTCVGATRDEVRAVVGDYAEAGIGNVLALRGDPPEGPQGPWR
CTPGGLEHAEDLVRLLHEEGDFCVGVAAFPEGHPSAPDRQTDIKYLVRKCAAGADFAVTQ
FFFSPADYFRLVEDAARLGCDVPIIPGVMPVTNVGQIERFAALSGATFPPRLAARLRAVA
DRPEAVRAIGVEVAATLCRQLLDGGAPGIHFYTLNRSTATREIYAALRLAHA
>A0A6P4XJV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panthera pardus|TrEMBL
MVNEPRGDGGPTSRSEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRH
IRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMW
GEELTGEESVFEVFACYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A109L468|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFSPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>R7T9Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capitella teleta|TrEMBL
MANTITNNTPISFEFFPTKTEDGARKLEQNALSLAKYQPEFFSVTYGAGGSTRDRTLETV
LSTQNQTRIATAPHLSCVGDSREQIKELLDFYRTQGVKRIVALRGDLPSGMGRDSGELRY
ANELVEFIRAETNDHFHIEVAAYPEVHPQAPNMEKDLENFKRKVDAGADSAITQYFFNAD
SYFYFLERTRSFGIDVPVIPGIMPITNYTRLARFSDACGAEIPRWIRKQLEAYGDDITSI
KKFGEEVVTQLCEKLLEGGAPGLHFYTLNQAAPCQGICDNLGISVS
>A0A174L0M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia obeum|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSVGMVRFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A0F4VFN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A3M4BJ71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. delphinii|TrEMBL
MRSLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDLVAFIREETGSHFHIEVAAYP
EMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFNFVERVEKMGVSIPIVPGIMP
ITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEDVITQMCERLLEGGAPGLH
FYTLNQAEPSLAVWNNLQLPR
>A0A2E5QTR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibacillus sp|TrEMBL
MQIADLFRSHQPSISFEFFPPRTEKGAESLLATIHELKKLNPSFVSVTYGAGGSTRDLTH
RLVLRILQETSIPAVPHLTCTCHNAPEIETILNQYAEAGVGTILALRGDPPREMPDYDRS
QDTFPYASDLIRFIQEFNRSGQHPSGGFGIGVAGFPEGHPETQNRMKEMDYLKAKIDAGV
DYICTQLFFDNHDFLDFRERCHLAGITVPIIAGIMPITTPGGMVRMAELAAGVHFPAKLQ
RDLTGLEDNPEAFAKAGTTYATEQCRELIEEGVEGLHFYTLNKSGATRQIAADLELGGSR
Q
>A0A1F2PCV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacterium wieringae|TrEMBL
MRITELFERGEFVLTAEVGPPKGVELDHLIKDAHEYLKTRVHALNVTDNQSSVMRTGSLA
TCRVLKDEGLLPIFQVTCRDRNRIALQSDILSAALLGIENLLLLTGDYTTLGDHPQAKPV
FDLDSVSLIHAVKRLEEGFDIAGNAVDGAPPKFAKGAVVSPCSDSVDVQLAKMEAKVKAG
CEYFQTQGVYEPEKFIKFMEQAKQFGVPVQLGLIIPKNVGMCRYMNANVAGVHVPDEMIA
ELQADKEKTKAGDTGVEICARLIRECKDYAQGVHIMSLGWENRIPEILDLAGIAPITPVV
>A0A4S3J2D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus tanneri|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AKRSLELAEICQRQLQLTTCLHLTCTNMSRALVDHALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRQQHGDYFCIGVAAYPEGHPADSFQDVQDPERDLPYL
VEKTQAGADFIMTQLTYNLDAYTKFEKRLRSHESGAFQTIPILPGLMPIHSYKILTRVTK
LSHVQIPPPMLDQLDRVRYDDDAVKRMGVDIVSDLVGGIRDISYPGPRGFHFYTLNLEKT
VSFILERCDLIPPLSEDDDDEAALVDGGHLSAVDSSTYVAPNGMPNQSLTRRRAESINSL
PHNRVIVDKVQAAESSSKDSVSHEAPATSAGMPALPPDRTTTLQISEGLGALGREATWDD
FPNGRWGDARSPAFGEIDGYGPSLHVPPPVGHRIWGFPVSREDVSTLFRRHLQGELHIVP
WSEGGTEEGASGLSAETDIIRPELLQLIDRHGWWTLASQPAVNGVRSDDRVFGWGPPGEG
FVFQKPFVEFFCPSSDYRSVLKPLLTHHGHEKLAWFATNVHGDFETSMPGPTSDADPLEM
NPANVNAVTWGVFRGKEIVSPTIIEEVSFRAWGDEAFRIWDEWRRIYPRGSASERFLDQT
KNDVWLVCVVGQEFGAGTEIGSQEEEDETKWMWRVLANSK
>A0A158PHA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Angiostrongylus costaricensis|TrEMBL
MVISANEREVTSRSNSGKLEKIDTLSAIPYIFPSKLLWDQITVVQVGQQSKYIPLHERIA
RRIRDKTPFFSLEFFPPKTANGVANFFTRLDRFNEGGPLFVDITWHIASDPANMNKETSS
SSIAAGCLDYCRVDTMLHMTCAQYSKEQTIKHLEQSKSVGLRNILALRGDLNNTDTDYES
TIYRYRALDMIRWIREEFGDYFTICCSGYPLGHPEAPSYKADLQYLKSKCDAGAQFIITQ
LFFEAEVFEKFVRDCREIGITVPIIPGIMPIMGYDSIRRIAMLSQLTIPQSILLDLEPIK
HDDDAVRKYGTIRATFIQAIEMCRRILANGSAPSIHLYTMNREGACRQMLQELGLWHKRP
MRALPWEPHGSNHPLRCKEDVRPIFWSARPKSYIYRTRDWDDFPNGRWGNSSSPAFGDLN
DYYLFHLKITQTKKEDLLKMYGEELLSFDDVKKVFKNFISQETNEHGVKVTSLPWNEKEI
GVQPETRLINEQLLWCNQNGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFIS
KENAKSLLEIIDEFSPRINYHLINHDIFFERVSLTIHQGSFDRMNGETTTPIAVTWGVFP
GAEIAQPTVVDPLAFRAWKDEAYDAWIKHWANLYPKDSDSRKILQKIHDEFFLLNVVDND
FQRPVIIYEMLEKMLRKTKENGASEGTPEESTNEYE
>A0A4D4MPJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces avermitilis|TrEMBL
MLASGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVKETEQ
IVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVPHPRGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSADWEADVERFVDKCRAGADYAITQMFFHPE
SYLRLRDRVAAAGCETPVIPEIMPVTSVKMLERLPQLSNAAIPSVLQERILTAKDDPAAV
RSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPQQA
>A0A2V4B0X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella muralis|TrEMBL
MFLTPREGTTSRLDLLRDFSLEMTGKDVNSLHEASSGIPTGTRVNVTYLAHEDLRLRVTA
ARSVRDLGLVPVPHVSARRLRSRGALDEFLGALRADGNTDRLFLVAGDPRTPEGPYTDTL
AIIESGVLEENGVREVGISGYPEGHPEIPDDTLWRSLEDKVFALHERAIDATVTTQFGFD
ADTVLHWVEKVRGRGVTVPVRVGVPGPAGAKRLLTYASRFGVGTSAGIAKKYGLSLTNLM
SKTGPDRFINTLGERYNEQRHGELHLHFYTFGGIQATAEWVLQYKESTP
>A0A448A817|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus vestibularis|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLGKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHGATHSLFKHHSQVSAL
>A0A1V8PQF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium catenulatum|TrEMBL
MHSPMFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVS
EYGIPSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFEHASDLAV
YIRQQRPGMKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KARTAGIDVPIEAGIMPVMNAKSVLNMSSKCQSKIPEKLGIMLDKWGSDKALLKEAGIAY
ASEQICDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A0G2ZY61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Archangium gephyra|TrEMBL
MKIRNRLNPSNPCFSFEFFPPKTDEGTANLLKTLEDLAPLEPGFVSVTYGAGGSTRDRTL
ELVTRIKRETGIEAMAHITCVGHTPGELRDVLQRLEEAKLENVLVLRGDPPRGQTAFEPV
PGGFRHASELVRFIREEDFNFCLGGACYPEGHVETASRDDDLRHLKEKVDAGLDFVITQL
FFDNAFYFDFVERARRMGINVPIVPGIMPITNYEQVHRFTRMCGATVPMRLGLQLERVKD
QPEALVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRART
>A0A6J5VIL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prunus armeniaca|TrEMBL
MKVIEKIQEALLEEKKVLFSFEFFPPKTEDGVENLLERMERMVAHNPAFCDITWGAGGST
ADLTLDIANKMQNIICVESMMHLTCTNMPVDKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQIQGGFACALDLVTHIRAKYGDYFGVTVAGYPEAHPDAIGTNGLASPEAYQSDLAYL
KRKVDAGADLIITQLFYDTDVFLKFVHDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPAEVTAALEPIKDNEEAVKSYGIHLGTEMCKKILAHGIRTLHLYTLNMEKSALAILMN
LGLIEETKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDLYPHGRWGDSRN
PSYGALTDYQFMRPRARDKKLVEEWVVPLRSVEDIHEKFKKFCLGKLRSSPWSELDGLQP
ETKIINELLGKINTKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKL
DALVEKCKALPSLTYMAVNKDGRWISNIGQTDVNAVTWGVFPAREIIQPTVVDPASFMVW
KDEAFEIWSRGWARLYPEGDSSRKLLEEVQNSCFLVSLVDNDYIQGDVFAVFADF
>A0A4S9SK86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEVTAPQAPQ
IVNGATNGEKHEEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A5F1F497|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E3659|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>B8NG74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167)|TrEMBL
MHIKEKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAAEGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLLPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIKDLSRLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLIE
LNNRGILTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDSWYLVNIVNNDFHNTYDLFELFKDLNVRDFDVEVAADNADLK
SQENETAETTAN
>A0A8G4EXG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRDDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A6I0CXW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella anthropi|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKSEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDVKPAAHLTCVDATREEVDRVVREFAALGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPSWLAERFE
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTEAAL
EVA
>A0A3S4P186|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKDQAPQFDIIGACYPEGHPDSANQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHEATHSLFKHHSQVGAL
>A0A2T1J3Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter radioresistens|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKLVHQDLQHLNPEFFSVTYGAGGSTRERTLAAIEEFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQNIKRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIRRFIEKVNAGANAGITQFFFNPDSYFYFL
DRLAKEGIHIPIAPGIMPIINASNLIRFADGTGAEIPRWIRKQLSAYGDDSVAIKDFGHE
VVLKLCERLIAGGAPSLHFYSMNQTEPTRQLVLDLGLA
>A0A7C8P8X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orbilia oligospora|TrEMBL
MQEKITDKIKALPKDATYFSLEFFPPKTPAGLQNLHARLDRMAKGLRPLFVNVTWGAGGS
TATKSLELASLCQSHGLTTVLHLTCTNMSKSVLDDALENAKLMGIRNILALRGDEPRQHE
YLDVTEQVRNGSGDNEFVYAIDLVRYIRKQYGEYFAIGVAAYPEGYAETAYPVAQDTARD
LPYLREKTAAGADFIMTQFFYDVEAYISFEKVLRNDESGVFKDIPIIPGLMPVQSYQIFR
RTTKLCSVKVPGTISSRIESVKADDEMVKEHGIQVLTEMIGKIRSSTESDGGLPRGFHFY
TLNLEKAVAFIVERCNLIPEIPTSNEVAVEDEDDEEPGLLTVNGGGAAIPRRSRRTSSII
SDPHNRVIVDTVSSARSELQAEAGEAGVPKILDPGSQEGNLAISEGEGSLGREATWDDFP
NGRWGDARSPAFGEIDGYGVSLHRTPTEALKLWGKPTSTKDISDLFVKNSKGELEAMPWS
EDILNPESFLITEELVKMNAKGWWTVASQPAVNSAKSDHPTFGWGPKNGFVFQKAFVEFF
ILDEEWTELKKKLENEGKEDVSFYAGNKAGDFQTNLASDSSLNAVTWGAFPGKEIITPTI
IEEVSFRAWRDEAFDIWSEWQRIYPLSSATSKLLGELKNKLWLVTIIHHDFVNTDGLWKD
ILGL
>D1PD75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri DSM 18205|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHAHATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMHHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDDDAKQLGIEWTTAQVQDLFEHGYNNVH
FFTVSAVDSVKQIAKILF
>A0A3G5L2V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pestis|TrEMBL
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIAIDYWNSGIRHIVALRGD
LPPNSGKPEMYACDLVGLLKDVGDFDISVAAYPEIHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFD
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A358EGG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MKSLVRDNRVHVFDGAMGTLLYSRGVFVNVCYDELNLSRPELVRGIHEEYINAGAEILET
NTFGANPVKLSSFGLEDRTEEINEQAARLAVEASSKAELSELTRGNDPDYSSGSTVAVAG
ALGPLGIRIEPWGPTSLDEAEAYFARQVDGLLKGGVDGFVLETFSDISELQCALRAIRAA
CELPVIAQMTVGPDGKTSLGTEPAHLAQAMEDSGADVIGLNCSVGPAVMLDALEDMAEVT
QLPLSAQPNAGLPRNVRDRKIYLASPDYMAQYARRMIDVGVRFVGGCCGTTPDHTRRMRD
SVAALQPKHPIVTIRDRANNSHSATNPVPLEQRSAWGRKLARGEQVASVEIIPPHSWDAS
AVTSPARELKVSGVDAVSIVESPRSRSRMGALSAALIVEREVGIETIVHYTCRDKNMLGM
ISDLLGAAAAGIRNVLVVSGDPPVMGPYPDTTVVFDIDSIGLTNVVQGLNQGIDPGGNTI
GAPTEFVQGVAINHGSVDQERERSRFEYKVDAGANFATTQPVFSPKALEQFLDATTPEIP
IVAGIWPLTTLRNAEFLANEVPGVHVPTELVDRMRRAHLSGADAALEEGVAIALELINAT
QDFVQGFHLTAPNRKVQVALRVLRESGILATA
>A0A2V7JNR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MSVTLKNLLADGKVHVLDGAMGTMLYAKGFFLNVCYDELNLKQPKLVQEVHEEYVRAGAE
ILETNTFGANPVKLGSYGLADDTEKINQAAAELARRASGGRASVIGAIGPLGVRIEPFGP
TSREEAFAHFRRQAQGLIAGGVDGFILETFSDVNEIHEALRAVRSLSDLPVIAQMTIGDD
GLTHYGTAPETFAKQLTDWGADAVGVNCSVGPAGVLEAVEKLVKATDLPISAVPNAGLPK
DVGDRKIYLASPEYMASYARRMIESGARIVGGCCGTTPEHIKKIRDYVASVVPRHQPVVV
SREAIAPPAGVEAVPLAERSRWGAKLAAGKLVTSVEIVPPRGVDPAPMLAQCRALKAGGV
DAVNVPDGPRAQSRMGVLPSAMLIQREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRN
ILIITGDPPKMGPYPEATAVFDIDSIGLTNLVYRLNHGLDPGNNPIGAPTKWVIGVGVNP
GAVDLDRELSRFAWKVDAGAEFAVTQPVFDPRQLEQFLKRVEQFKIPIVAGIWPLISLRN
AEFLANEVPGVSVPEPVLARMRQAQDKGKEAALAEGVKIAREMFEQVKGTVQGVQVSAPF
GKVEVALEVFG
>A0A2V5W6Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRGDSPTFSFEFFPPKTPEAAEILYQTIRDLESYMPHFISVTYGAGGSTRDLTH
DLVERIQQTTKLDPIPHLTCICHNEDEIEAILLRYARSAIGNILALGGDRPRDIPYDKSR
DSFQHAVDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYMVTQLFFDNRDFLDFRERCALADIRVPIIAGIMPVTSLNGFKRIAELAGGARFPAKLL
RALQRCENDPEMVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRVIFDSLGIPRRR
KRTGPDRLVERYHV
>A0A1Q8ED07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus acidominimus|TrEMBL
MVHTPSLSFEIFPPNPAAGNEKILSALHDMQDLAPHFISVTASNNKFNIEETTVRLADYI
HNDLGIPSIAHLPAIYLTKAQVSNILTALDQIGVHTILALRGDRIPNVAPKNDFRYATDL
ISFIKEEAPHFDIIGACYPECHPDSPNSISDIKHLKKKVDAGCSSLVTQLFFDNDVFYDF
QEKCQLADIDVPIVAGIMPIINRNQALRLLHTCENIRLPRKFRAILDKYEHDPESLRAAG
LAYAVDQIVDLVTQDVAGIHLYTMNNPQVANYIHHATYSLFKHSAV
>D6AWV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albidoflavus|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVTAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A637XXN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Bareilly|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0F5LRL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia limi DSM 17137|TrEMBL
MIDDNLRASRQTAATRPELQLSFEFFPPKTDAMEERFWDSIHKLAPLNPRFVSVTYGAGG
TTRERTLRMVSKIKTDTGVDAAAHLTCVGASKDEVDAVIRGFQAAGIGRIVALRGDPPEG
IGRPFTPHPEGYQNAADLVAGIRRIGDFDISVAAYPEKHPQSANWQEDIDNLKRKLDAGA
TRAITQMFFNNADYLRYLDRARSAGITAPIVPGIQPIHSFKQISGFAARCGASIPDWMAE
RFAGLEDDPETHALVAAAISAEQITELLDEGVTEFHIYTLNRSNLALALARFLGRRPG
>A0A502JGM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus haemolyticus|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIESYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPS
>A0A7V1BBQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter litoralis|TrEMBL
MTSPAVSFEVFPPKSVDASFRLWDTAQALAPLAPRFFSVTYGAGGSTRDLTHDSAHVLRR
TSGLPVAAHLTCVGASKAETLEVANSFAEIGVTDIVALRGDPENGAATFTPHADGFADSV
ELIEALANTGKFTLRVGAYPEPHPESPDQAQNVEWLKRKFDAGADEAITQFFFETETFLR
FRDACAAAGITKPITPGIMPVTNWKSARNFATRCGASVPAALDEAYAAAIRDDRHDLLST
ALCTEMCSELVSEGVENLHFYTLNRPELTRAVCRALGVTAQTSLSDVA
>A0A269Y331|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus parakefiri|TrEMBL
MSLTGLFKQKTVFSLEVFPPKKDSPTDAILPTLKRLQSLQPDFISVTLGAGGTDHCNGTV
TIADLIQNQLNIPAVSHVPGLYQTKEQVLALLDRLDSINVKNILALRGDRIPGKTPVGDF
SHANELVHFVHERRPDFSIASACYPNCHTEAADFVDDIGHLKEKVDAGADHLISQLFFDN
QAFYDFKEKTEIAGINVPIEAGIMPCTNKNQIERITQISGVPIPKKFAAIMDRYQDSKEA
MLDAGIAYAVDQIIDLVSQGVDGIHLYTMNKSKIAKRIWEETRSVFEASSQSATRPG
>A0A7W6TDG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium cellulosilyticum|TrEMBL
MNETTTRPRFDISFEFFPPKSEEMEAQLFETVDRLALFQPEFVTVTYGAGGSTKEPTLSA
VTGIIDKTNLATAAHLTCVDASKDEVRSVVEEYRAAGVRRIVALRGDPTAGIGTTYLPHA
DGFQRTADLVQALAEYGDFDISVSAYPEKHPESRNMAADISVLKQKADAGAHRALTQFFF
DNEVFFRYMDEVAAAGVTIPVIPGIMPIQNLTQLKRFSKRCGATIPGFLDERFEGLDDNP
DDRAKVAAEVAAEQIEELGRNGFNHIHLYTMNRSPLVSAVLDNIGHKPGMRKAAA
>A0A0M9AI58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula rubripromontorii|TrEMBL
MALGTRAVSNSQGVQTLLTSARFELMPFESFDEEITHLPDDATIAITTSPQLGIEKTVEK
TEQAAAMGYDVVPHVAARYVEDRAQLEAIAERLDQAGITDIFVPGGDREEPAGEYESALD
MLEALAETEYSFEEVGITGYPEGHDFIDDETLAESMAQKAPYATYIVTQLCYDPDAVLEW
VEEIRGRGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDDEYNIRGVHIYTFNQTPDTEKWRHKRLDS
>A0A3E5DTQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHTHATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDEDAKQLGIEWTTAQVQDLFEHGYKNVH
FFTVSAVDSVKQIAKILF
>A0A1C4XHK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora carbonacea|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTAQGERLLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVR
GDPPGDPGGEWVRHPEGVLYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAVTQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQLSTIERSVQLSGAPF
PPALAARFAEVADDPEAVRRLGIEQAAEMCRRLLDEGVPGIHFITLNRSTATREVWQQLQ
VGAQV
>A0A076NL49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium imitans|TrEMBL
MRGTLPSTRLSASAPLDSLGEAPVTPQRRARTALSFELIPPRHDADSGKIDELIAGLAAY
NPDYVAVTSSRRSDWLTGTAALIARVAETTNLRPIAHLACTAGTREELVTWIRTLIDAGV
RGFLALRGDLPETGMPAHYLQHATDLLNLIQDVEDEEAFRLAAGKLALSVACYPSGHAES
KNFDEDLDVLLAKQRLGADFAITQLFFNAQDYLDFVEVARLAGVRIPLIPGIMPMTSLKR
VQRMGELSGIAVPECVTRTLAQATTPEEEYELGMQMSAQLANTILDAGTGGLHVYTHNNL
AVTQDLLDRIGIVQPAGHSLI
>A0A3V5ZEP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Haifa|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1H6B892|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobellus limi|TrEMBL
MTTSQRSSAAAGTAAALLESPRFELMPFDSFDDEIEHLPDGATITITASPQLELGATIDA
AERAAERGYEVVPHVSARYVRDSEHLAEICERLKAAGIEDLFVPGGDREEPIGEFASAYD
MLVALDDLEYEFEEIGITGYPEGHEFIDDETLAEAMKEKAPYATYIATQLCYDPDTILEW
IETVRDRGVDLPIEVGIPGVMKYEKLLSISQKVGVGDSVRFLKKTTGLVGFVKQFIGSRG
RYRPDELVDGLAPYADDPTCNIRGLHVYTFNQVPDTEEWRTGRLQ
>A0A497Y3V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter alluvionis|TrEMBL
MKITDHIKNAKGKTLFSFELLPPVKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QANGLLQKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHCYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMSTDFKYLKKKVEAGAEFIVTQMFFDNQKYFDFVKKCRENDINIPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNNEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKKIAKAIF
>A0A2A2AT77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vandammella animalimorsus|TrEMBL
MSASAPSHPQTPGAALSLEFFPPKTEAGAHKLRATRQALYPLQPQFCSVTYGAGGSTQAG
TFAAVREILAEGQQAAAHFSCIGATREKLRAELAELQAMGVRRLVALRGDLPSGYGLGGE
FQYASDLVAFIRAETGAHFHIEVAAYPEMHPQAASPEKDLQAFATKVRAGADSAITQYFF
NADAYFRFVDEARRLGLDLPIVPGIMPIHAASQLLRFSDACGAEVPRWVRSRLLAYGDDT
ASIQAFGLDVVTQLCQRLLAAGAPGLHFYTMNQSPLVLDIARRLGLLPH
>A0A429UJG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC05374|TrEMBL
MALGTPSTRTDRARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATQEIAADTTLTPVAHLTAVDHTIAELRNMIGQYADADIRNILAVR
GDPPGDPMGEWVPHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFFPEDYLRLRDRVAALGCETPIIPEIMPVTSVKQIERFAQLSNAHF
PPELKERIHAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHEQS
>A0A6P5J5B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phascolarctos cinereus|TrEMBL
MKPEAAALRRAAVVAVKVPKTAPAVPPQCWMLSGMSDFERRCTGGWTQGTGGSPWSFSLL
ELPREQSISSLAVDYCGLETVLHMTCCHQTRDEITSNLHKAKRLGLKNIMALRGDPMGDE
WEEEENGFCHAVDLVKHIRSEFGDYFDICVAVISPNSSPCLSGAESHLRRSERHAQQVKV
MMGQASWRLNLVRNLRGHVVQPFLGTPLSSLPNHFPPRLCWNVAINGYPKGHPEAASFEE
DLQHLKEKVSAGADFIITQLFFQADTFLNFVKACTAMGITCPILPGIFPIQGYHSLRQLV
KLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVAMCQELLASGLVPGLHFYTLNREVAT
VEVLKRLGIWNEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQAWDEFPNGRW
GNSSSPAFGELKDYYLFCLKSKSPREELLKMWGEELTSEESVFQVFTYYLSGEPNQSGHK
VTCLPWNDEPLAAETSLMKEELQKVNQRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQ
KAYLEFFTSSETVAALLQVLKKYELRVNYHIVNVKGENITNAPDLQPNAVTWGIFPGREI
IQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYHLVNLVDNEFPLD
NCLWQVLEDTFELLSRPAPQ
>A0A5J6RHS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter cibarius|TrEMBL
MFETLIQKLQEDRYLTLETTPQHEPSMHNIIEKIKKFKIDTKVDGFTCTDNPLAKLKYSS
LFAALKLQQEFKKPVIATVAMRDRNKIALQSDLLGANDFDIRAILALTGDPANMSDQPNT
KGVYEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFAVVNAYAKNFGSLEKKMNQKI
QNGAVGIITQPVFDIENVKKLLEYFENAKENVDGEKKKAQLILGLFPITKLRTALFLSAQ
VPGIHVPQFWIDELEKAHSISEEEEYKVGMQLSQNLYREINKIHPKIHLMTANNKFDVAS
EIIG
>A0A6G2J941|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MLLLKDASGRRRLLQHAQWELIPLRNLAEQLPHLPPQSPVSVTASASKTLEDTLDLTAEL
CALGHHPVPHVAARMVTSRDHLEELLGRIESMGLSEIFLVGGDVASPAGPFDSAVGLLEA
LREVSHSLVHIGVTSYPEGHALITDAVLHEALHVKQVLLAEAGIEGHAATQMCFHPKAIL
EWLTAERDSGLNLPVHLGIPGAVDPARLLRIGTRLGVGASLRYLRKNTGAVARMLRPGGY
DPSGLVDRIAPHAERLDIAGLHVFTFNAIADTVAWRESALAETSSRRR
>A0A1L0GKN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] intermedia|TrEMBL
MATVTDQIKALAPGERFCLFEFFPPKTDAGFRNLLARLNRMLALNPLFLTVTWGAGGSTS
EKSLDLAATCQNDLGITTVLHLTCTNTNKEVIDNALARAKSAGIRNILALRGDPPRTKEY
WTPNCDFNNAVDLVRYIKAQYGDYFCVGVAGYPEGHVDGADTTHQDPARDLPYLVEKVQA
GADFIITQLFFDVDKFVAYEEMLHNTPELKDTVLIPGLMPITTYKVFTRATKLSHALIPE
DIFSRLEANSSNDDTVKDIGIEVLNDIISQIDERTQGRVRGFHFYTLNLEKAVASIIESS
PVLNLQNHNLAVDHDDAISLDSDSEPLPPLKSTRRRSSVNENWPAKNGLDAKRALVTKAL
SRDRKTLVDISKGKGVLGKDATWDEFPNGRFGDSNSPAYGEIDGYGPSLKLHSNKEVLDT
WGEPKSIKDITKVFVNYLSDKIQVLPWVSSELSPETALIQEQLFEMNEKGWFTLASQPAV
DGCPSSDSILGWGPSNGRLFQKSFVEFFVPKQEWDTKVKPRLQEDIDSTTITYFCGDASG
HITSNLPIGKDTHNRKSAVTWGVFPSKEVLQPTVIDYESFKAWNEEAFLLWLEWARCYKK
DSDAYKLLNSVYSDYYLVSMVHHNFMDEYALWNSLLD
>A0A2A4EHR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus pseudintermedius|TrEMBL
MSRLLNALKNNILVADGAMGTILYSEGLDTCPEAYNLTHPDKVESIHRSYIQAGADVIQT
NTYGANFEKLQQFGLEHQVKAIHQAAVAIAKRAAGPDTFILGTVGGFRSTKQGELSLSAI
QYHTDIQVDTLVAEGVDGLLFETYYDDEELLNAIKQTRQKYDIPIIAQLTASNTHYLVNG
KEINSALQQLVEAGADIVGLNCHHGPHHMKRTFGHIELPDNAYLSCYPNASLLDIDQQTF
KYSDNAQYFGETAEQLIQEGVQLIGGCCGTTPEHIRKIKAAVQGLKPIKEKKVIPIHQKP
TSEAPKPTRQNLAMRVRERPTIIVELDTPKHLDTTKFFQNVKALDDAQIDAVTLADNSLA
TVRVSNIAAASLIKQQFNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGVNTDGDTLKVATQFNIAGGFDPHVSNIKAAVRK
METKIKSGMHYFITQPVFTKEKIVEIYEATKHLDVPIFIGIMPITSYKNALFLHHEVPGI
KMSDDVLAQFEAVANDRQATYELSLSLCKSLIDTVHTYFNGLYLITPFERIDYSLELAAY
SKSITTSHQEAIL
>A0A2W1GE51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenophora tritici-repentis|TrEMBL
MHISKKLTQAREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQTVYGLETCMHLTCTDMEKSKLDDALREAYQSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGGTF
IVTQMFYDVDIFLEWVRKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTRCNIPQHWTDAL
EPVKNDDVEVREVGKMLVADMCRKLIAAGITHLHFYTMNLAQATRMVLEELDLLPDVEAP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNVKLWGSPMCIRDLSDLFVRYMEGKLDSLPWSEQAITTEAGPIRSDLID
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDIVDTWYLLNIVHNDFHETRGIFPIFDGLEVKDMDKPLHNPSVDL
PGVNGTESTNGTNGTNGDAEAPGLIETAKAAAVEVTNGIKSLAVSN
>A0A3D5IDF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MRIASILNEKEITLSCEVFPPKHFDGIAQASAVAQEIAGLHPSFMSVTYGAAGSTPGHTI
AVAKAVAETGVTPLCHLTCVQSTREHVQHVLADMKTAGMENVLALRGDLPKEGEPCHDFA
YAAELIDFIHQQGDFCVGAACYPEGHPESGSRAKDMDYLRRKVDAGVDFLTTQMFFDNGL
LYNFLYRMQRAGMDIPVCAGIMPICDARQVARVVKLSGSIMPPRFAAIADRFAGDPQAMT
QAGIAFATEQIVDLVANGVGHIHLYTMNKPWIARAIVENLSSIIKLGE
>A0A5I3V6A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Mississippi|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6L8D671|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSHLSDSLTHKPFTLTAELNPPKGTGLDDLFAAADALKDSVAAFNLTDSAASRMAMAPLA
VARLLKDRGVESTLQIAGRDRNRLAIQADMLAAHALGVENIVCMTGDPPSGGDHPDAKPV
FDLGAEDILKAAVSLESGHDLAGNALKGSPHFLRGAVVNVAVPDLGKEIGRMEGKIDAGA
EFFQTNAVYDPAGFEAFMKQVEGLKVRILAGIILLKSARQARYMTEKIPGVVVPDPLIDE
LESAESRVATSVAMAGRIVQNVAPMCQGVHIMAIGWEHRIPAVMEAAGF
>A0A432FR86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
METQYSFELFPPKTEKGMEKLKGVVTELNALEPAYFSVTYGAGGSTRERTFATVDWLRGQ
GIDTAPHLSCIGAGREEILDILNRYRNEGIRRIVALRGDLPSGAGLGGLGEFNYANELVA
FINANFPGEFHIEVAAYPEFHPQAESAWKDLDNFQRKVEAGAHGAITQYFYNADAYWRFV
EDCEHRGIEIPIVPGIMPITNYVNLARFSDACGAEIPRWLCKRLEAYGEDLESIFDFGVD
VVSDLCARLLDNGAPGLHFYTMNQSAAVKAIWSRLGLDGGAAGA
>A0A0E1EID0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas chlororaphis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQTFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A4L7TUI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILAKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A150MRS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus stearothermophilus|TrEMBL
MGLLDELKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALIRLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTYRSVIVELDPPKQLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKEQLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVYEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACGSDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A0L0KKA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces acidiscabies|TrEMBL
MALGTASTRTDRARTVRDILASGKTTYSFEFSAPKTPKGERSLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMADWIAHPSGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSDHWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEIMPVTSVRMLERLPQLSNAAI
PSALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTASLEIYENLG
LHHPPRA
>A0A356NQS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MEFIKDIHREKIATGKPAISFEFFPPKTEKGEAQLFHAVLPELLKIQPDYCSVTYGAGGS
TRGKTLEMVSRIQKDFQLTCMS
>A0A356CRU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilaceae bacterium|TrEMBL
MPKKISYSFEFFPPNTPEGIKNLADTRQQLSVFKPEFYSVTFGAGGSTRDRTLETVLEIK
KEGFNAVPHISGISSTKAEIKTLLDQYQQHNIRHLVALRGDVPQGEVPSGEFRHANELVS
FIRQETNDYFHIEVAAYPEYHPEAASAQIDIQNFKNKVAAGANSAITQFFFNADAYFRFM
DECLIADIDVPVIPGVMPIYNIKQLARFASNCGAEIPRWLRIKLESYGDDLPSLRSYGVD
VISELCEVLIGWDVPSLHFYTLNQAGIISRIIQNIEGA
>A0A6B1EJ39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNGPARISLEFFPPRTEELTAMLEASLKRLLPYRPLHCTVSYGAGGSTREGTARWVRRIR
QDYGIDCAPHLTHVSHTRDEVREIVRDYVAQGVRRMIALRGDIPADGVPDEVRERGYSST
VELITDLRAAGISEVMVGAHPEHGGGDSASLRRHLEFVKQKLDAGATLAITQFFLDNDRY
YRLRDIFAGAGIEHLLAPGIMPLHNYRQVFSFAGKTHVEVPAALGARFEQAGEDPDAVSE
IAEGFSLGQVRDLVENGVERFHIYTMNRAPLTAAICEALGLSAPGTQS
>A0A6N8UJC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSAANFHLSFEFFPPATAIGQTNLAKAAETLQRFGPEFFSVTYGAGGSTKTRTKETVAGL
ISNGCTTVPHLSWGDSPREHLVEQLRDYRELGVSGLVLLRGDAPSGTVAQTGHHAAELVG
LVRTDFGDEFEIFVAAYPETHPDAPNPTKDIEFLRAKVDAGADACFTQYFYNPDAYFYFV
EECRARRIDVPIIPGVMPITNCERLVRFSRNCGAEIPRWIESKMFEYKDDQESLEDFGCT
VVRNLCQRLLDNDCPGFHFYTLNRARATSRILQNLGY
>A0A0D8J659|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruthenibacterium lactatiformans|TrEMBL
MFIHEMFQQKPCVFSVEVFPPKKAGAAEETLYPVLRELCTLGPDYISVTYGAGGGTAGQS
TAKIASYIKNGLHVEALAHLTCVNSTRVQVEETLTRLREDNVENVLALRGDINPDLPRRM
DFLHASDLAKAIAQTGGFGVAGACYPEGHVESPSLKADVESLRYKAEAGVSHLITQLFFD
NVSYYRFLNMARKAGISLPVQAGIMPIVSKRQIERTVALSSASLPPQFTKMISRYDHDEQ
ALFDAGIEYAVTQIRDLITGGADGIHLYAMNNARVARLVYEGIRDLLPERT
>A0A5N7CES4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petromyces alliaceus|TrEMBL
MLPLPLIGGLVKLRPERFAPRLMTPQSSSFNYHLFHTFAGTDTGDKMEKITDKIAALPPD
ANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGTTAQRSLELAEICQRQ
LQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNKDFT
FAVDLVRYIRQKFGDYFCLGVAAYPEGHPVDSFQDVQDPKKDLPYLVEKTQAGADFIMTQ
LTYDIEAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVKIPPHILSKL
EEAKHDDDAVKRIGVDIISNIVGGVRDIPSPGLRGFHFYTLNLEKTVSFILERCDLIPPY
SEDFDALEDGGDISAMDGAQLRSLTRRRASSINSLPHNRVIVDKLQISEGSSKASVSHEA
PATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLH
VPPSVAHRIWGFPVSREDISTLFRRHVSGELHMVPWSEGGAEEGSPGLNAETEIIRSDLL
KLIDGNGWWTLASQPAVNGVRSDDPIFGWGPPREGFVFQKPFVEFFCPSEDYQSVLKPLL
KKHGHEKLAWFAANVKGDFESSLPAQTSDADPIEMNPNNVNAVTWGVFRGKEIVTPTIIE
EVSFRAWGEEAFRIWDEWRRIYPRNSATERFLNDIQHDIWLVCVVGQDFGAGTEMGSEDE
EDEKKWMWKVLANAK
>A0A0F5EXJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Avibacterium paragallinarum|TrEMBL
MSYAKEIDTLNHYLSGVNGNINVSFEFFPPKNENMEKILWDSIHRLQVLKPKFVSVTYGA
NSGERDRTHSVVKRIKQETGLEAAPHLTGIDATPEELKRIAQDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPAWLAKMYEGL
DDDPTTRNLVAASVAIDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A5K8IXC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAAIGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEQGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDDVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A5J0VDZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Agbeni|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0C3R6T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sanguibacteroides justesenii|TrEMBL
MKVIDILRKSDRPIFSFELVPPLRGGDIHRIYEAIEPLIKFAPPFINITFHRDEQEYRER
ADGSIVKVTVTKRPGSVALSAAIMKRYPVEVVPHIVCGGATRHSIENDLIDLNFLDIENV
MALRGDPVSGQRYFTPEEDGHKYSCELVEQIARMNQGKYLDDTLTDAVPTNFCIGVAGYP
EKHYEAPNPVSDIENLKRKVDAGADYIVTQMFFDNDNYFSFVEKCRAIGISVPIIPGLKP
ISSFKHLENLPRSFNLDIPEELERAIRRCRSNKEVYRVGIEWCIAQSQELIRQGAPAVHY
YTMGKSDNIQEIVKRVF
>A0A063BY25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ustilaginoidea virens|TrEMBL
MHIKDMLSEADKNGQPSFSFEYFPPKTAQGVQNLYERIDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLDKVDDALQRAYKAGCTNILALRGDPPRAQET
WTAAEGGFQYARDLVRHIRATYRDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVARVRERGITVPIVPGIMPIATYASFLRRAKHMQCRVPDAWMAAL
EPVKNDDAAVREVGKSLVAAMCRTLLASGIRHLHFYTMNLAQATRMVLEELSWAPCPERP
LKQALPWKQSKALGRRGEDVRPIFWRNRSKSYVLRTQDWDEFPNGRWGDSRSPAFGQLDA
YGIGLTGTNEANRNRWGEPTTVQDMADIFVRYLDRDIDSLPWSEAPLTSEADAIKDRLIA
LNRRGLLTVNSQPAVDGVKSSHPVHGWGPPNGYVYQKAYLELLVPASILDEMVARIEAEA
ATTTLTYYAVTKDGQLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLG
TDWAHCFEAGTPTRVLLDQVMNGWYLVNVVNNDFHENDTIFELFDGLEVKGLDVPVSA
>A0A6L6EKA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTIPSVSFEFFPPKDSEGESRLWEAMMNLRSIAPDFVSVTYGAGGSTRDRTIEITTHITE
RTSIPTVAHLTCVGSTQEEIGEILMRYRDAGIKSILALRGDPPSGPSTPWTHTPGGLDHA
DELVALAAEFGDFTIGVAAFPDGHPASHGNFDQDVNVLLRKEELGASFATTQFFFDVNKW
ISLVNRLKERGSQLPIIPGILPISSVKQLVRMAELGGTPIPDDIHAKFLSIESDDAAVKA
LGIEIATKLCIELLDAGAPGLHFYTMNSSAATREIWENLGLKR
>A0A0J6EML3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus glycinifermentans|TrEMBL
MGLLEDIKSKTLIADGAMGTLLYSYGIDRCFEELNVSKPDEVKRIHEAYVKAGADIIQTN
TYGANFIKLSRYGLEDETKQINEKAVRLARSAAHSAYVLGTLGGIRTFNKNKYSLDDIKR
SFREQLYLLLNEEPDGLLLETYYDLEEAREVLKIARKETNLPIIVNVSMHEEGVLQDGTP
LAEGLALLAGLGADVVGINCRLGPYHMIKALEEVPLLKDAYLSVYPNSSLPSLVEGRLVY
ETDDAYFRNSAVEFRNQGARIIGGCCGTTPNHIRAMAEAVKGLPPVTEKRVKTREKAAAA
VQRERTEPALDELAKEKRSIIVELDPPKQLNFEKFLRAAKELKSAGIDALTLADNSLATP
RISNVACGALLKERLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRIE
KKIDCGADYFISQPVYSEEQLIKIYEETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDAIREKMALAGSDKQKQAEEGLAIARSLLDAAYDLFNGIYLITPFLRSDLTAELTTYIH
QKEKETTNVYHH
>A0A1X1GGD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. tigurinus|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A0D5YHC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHLSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKVKAGADFIITQLGYDIEAL
KQAKSFLTKHNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQVGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVT
TSKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A3R0KZP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAKADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>D8DZY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella bryantii B14|TrEMBL
MNISEILNSSNAQKHFSFEVLPPLKGNGTDGLFRTIDKLKEFNPLFINITNHSFEYIYQE
LENGLIEKSRIHRRPGSVAIAAAIQNKYNIPVIPHLICSGATKEDIEYELLDIQFLGIET
LFLLRGDKAHEDNRFKAVPGGYDHATELIKQVNQFNNGYFVDGTPIKHPGKKFEYGVACY
PEKHNEAPNLDIDLKYLKEKQDLGATYAVTQLFYDNKKYFDFVKKAREMGITIPIIPGIK
PFAKLSQLSVVPSVFHIDFPEELANEAMKCKNDEEAKQLGIEWTTHQVKELYTNGVNDVH
FYTVSAVDSVKEVARRLL
>A0A2J8KXC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pan troglodytes|TrEMBL
MDHRKARVLPAGHYCPSLGIWASQVGSVRSSVPPSISRNPAMVNEARGNSSLNPCLEGSA
SSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDICVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRSIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDTLELVNRPTQNARETEAP
>A0A8G8W8W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carnobacterium maltaromaticum|TrEMBL
MGLKEVLGTKLLIADGAMGTLLYQYGIDRSHEELNCSHPEAILKIHQDYLAAGADIIQTN
TYGANYIKLARYGLEDQVQKINRAGITLAKEARGDKEAFILGTIGGIYGAVDTKIHDPGM
EEISRSFKEQLYCLLLGGVDGILLETYYDLNELKTVLAIAREATDIPIIANVSIHEVGIL
ANGQSLATALEELADLGANVVGTNCLLGPHFMAQSFESVPLIPGKVLAAYPNASFPTMEN
GRIVYQKETDYFKLFGELFRKEGVGLIGGCCGTTPEHIAAYREGLTTLDLVTQKKVKALT
TYRFQAKQETGKERLLDKVQREYTVLVELDPPRTFNTTAFFKGAARLKEVGVDAITLSDN
SLASARISNMALSAMLKYEYDIQPLVHLTTRDHNLIGLNSQIMGFHKLGIQDVLAVTGDP
AKVGDFPGASSVFDVSSFELIKLIKNFNQGIAYTGKNLREKTNFQVAAAFNPNIPRLERA
GRLLKKKQEAGADYFITQPIFDSEKVKILKEVMKTAGVTIPIFIGVIPLVSSRNAEFLHN
EVPGILLTDETRERMRMAEEEGRGLEVGMTIAKELIDEICQEFNGIYLMTPFMNYEISAE
LCEYIQAKKQQEKSICSCGQVHSQ
>A0A2N5PXI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus gnavus|TrEMBL
MKIIDRLREDGIHISFEIFPPKTDAGYDKVIRAAEEMAGLKPEFISVTYGAGGGTSKNTA
KIASYIKHDLHVESLAHLTCASSTKDEVRSVIASLKEQGIENILALRGDISEDMVFPSED
RFHYACQLVEEIRRHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSARQMKRSCELSGTVFPRRFQAILDRFGDSPK
AMEQAGIAYATDQIIDLLANGVKNIHIYSMNRPEVAAAIMHNISEIIQC
>A0A842G6B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKILIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVAEQIISQN
>A0A6A3YRW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora fragariae|TrEMBL
MPRVSSIHVTKQKERHEEADELAATKFVLDDSTVWTGLSTEDTRAAGESEGDQERLLQRL
HLVQGLLTFVRMLRRSRGLQAEEEDDEAKTSAQWTPEWASLKRALGLQRLKAKQDAGADF
IITQFFFDVDNMIHWIADCKDAGITILPGYLSIQNYSSLCKFTSWCKTRVPESVLAALDT
IKNDDAAVRRYGTQLAAETCQRLLAAGVNSLHFYTMNLPRP
>A0A135ZQU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium sanguinicancri|TrEMBL
MGYSHASHLEALNQNIVDLKGDINVSFEFFPPSSEQMEKTLWASIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLVAAPHLTCIDATRDELRTIARDYWNSGIRDIVALRGD
LPPQGGKPDMYAADLVELLRKEAEFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNMTQAKRFALANNVKIPGWLEKQYE
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAEVDIAS
Q
>A0A3M6Z3B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMNYDAEIFIEWAKKVRAAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAELFVKYMSGKVETLPWSEQPISPESNVL
TNDLVNLNSRGLLTINSQPAVDGMKSSHPVYGWGPNNGYVYQKAYLEVLIPPSLIAEIIR
RMDANPDITYYAVNNSGELKTNAPQDGGPNAVTWGVFPGKEIVQPTIVETISFLAWRDEF
YHLGSEWAKCYDEGSRSKNLIKEITESWYLVNIVDNDFRNMRGIFPLFDGLKVDGVEPTA
AAAVNGVAHANGDANGDVEKKEGSQKPEVNGVPDRNNAVNHADGAAVNGQQVKN
>A0A2K9EGJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetivibrio saccincola|TrEMBL
MRLIDLFKTKKPVISFEIFPPKLDMPLDSIYDKLEDFKKLKPDFISVTYGAGGSAKDRTI
EIASKIKKDYKIESMAHFTCVGHSKEEIDSLIDSLENEGLENVLALRGDPPRDQPDFDFS
KNVYQYASQLIEHIKKRSNLCIAAAAYAEGHVDSPRIKDDLINLKNKVDTGVDFLVTQLF
FDNRIFYDFLDRAISLGITCPVTPGIMPVFRADQIKRIASLCGASIPAQLVIIMDKYGGN
PDDMLKAGIEYACMQIQDLIDNGVDGIHLLTMNRAKSTRKILENLNLLQK
>A0A7D6VQE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRIIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1I4XWZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides xylanisolvens|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIDKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHALELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMDHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A2S7V8Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio jasicida|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDATRDELIDIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A378B7B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae subsp. ozaenae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A177RKK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia solanacearum|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRSILDTYREHGIRRLVALRGDLPSGMGEIGEFRFANELVEF
IRKEMNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>C3SIT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A418A5N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira yasudae|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDVKLMETVKELSRLNPDFVTVTYGAGGSTRDK
TVQILSEISKNYSVPTVSHFTCVGANRDQIRETLKGIRSAGIVNLMALRGDPPKGEGEFK
KTEGGFANATELISFIRSEKMDFCIGGGCYPEKHPNAKTLEEDVRNLKLKVEAGTDFLVS
QLFFVNSIFENFLNLVRKVGITIPVIPGIMPITSFSQIERFRSLAACEFPSSLIEDLQEV
EHRPEEFYRRSLNFTVKQCRELLAMGAPGIHLYTLNQSHASYDIVRELKG
>A0A6N8NNI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
PHLTCIDATPDELRTIARDYWNNGIRHIVALRGDLPPGSGKPEMYASDLVTLLKEVADFD
ISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVE
IIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSR
EGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6N1BIC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus gilardii|TrEMBL
MQDRYYSFEFFPPKTPEGREKLRNTRAQLAPLGPKYISVTFGAGGTTQQGTLDAVLEIQR
DGIDAAPHLSCVGSTREGIREILRTYRDNGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFQIEVAAYPEYHPQARSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRALGVDVPIVPGIMPITNYAQLMRFSEMCGAEVPRWVAKRLESFGDDREAIRAFGLDV
VTALCERLLAGGVPGLHFYTLNAAGATKAIWQRLKL
>A0A166R9M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1N7UT48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas simiae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISTMCEDLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A4Z1AIC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira congkakensis|TrEMBL
MNKILLEVIPRDTPTLLSEVGYVKNNFSQISGINIPDLLRFETRSWVAASKIQNIFPNVI
PHLRAIDFDLDHCDHIIEFLQKNSISSVVVIKGDPPTDMSRKVYQTTSTKLIKKLKKEMS
SLKVYAAVDQYRSGIKDEFDYIEMKIDAGADGFLTQPFFDLRLIDIFTEKLRGKEVYIGI
SPVTNEKSQSYWESRNRAYFPRDFQLTMDWNVKFAKEVIGYCSQNDFNTYLMPIRINLEV
YLSGIFK
>A0A0S4UNA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia solanacearum|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILDTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRKEMNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>A0A818SF76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sordida|TrEMBL
MEFTVSDNQAVPNNHKINGVETHLQSTCDLNGFKRIESEGANISAKGCCLQPIKYVSLKE
KILKRIADHDRWYSLEFFPPRTPSGAANLIGCFDRIAAGQPLFCDITWHPAGDPASNKET
SSMMIANTMLNYCGIDTMLHITCYGAKKANMLEYLYKAKDCGIRNLLALRGDPLVGEEWD
AEKSDFRYAVDLVKFIRQHFGDYFVICVAGYPQGHPDSTSYEDDLSYLKKKVDCGADFII
TQLFFQPETFLKFESDCRAIGITCPIIPGILPIQGFASLRNIVRLAKLDVPKEILACIEP
IKDNDEAIRNFGVQTCLDLCRTLLESGKVDGLHFYTLNREFATIEILKKLGLWLEEQTLR
ALPWKKTSFSHARSKENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGALTDYH
LFYMKIDATRDELLDEWGRELTCEQDVWNMFACYVGGEKNSLNKVVRHFPWTDDELALET
GLIRKELVEFNSQGILTINSQPAVNGKPSLDPVVGWGTPNGYVYQKAYLEFFTNEGNIPA
LRAVLKKFPGVNYHFVNKSGEISETNADDEQPIAVTWGVFAGREIIQPTVVDPVSFMIWK
DEAFSLWTERWGKLYEQESCSRAIIDKIANTYFLVNLVDNDYPQGSCLWQILDSMFEYQK
LSNKHIDS
>A0A2B7MML9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia marmotae|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPSGSGKPEMYASDLVELLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A223E5M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeribacillus pallidus|TrEMBL
MGLLQDLQNHILIADGAMGTLLYSFGIDRCFDELNVSKPEEIERIHSAYLDAGATVIQTN
TYGANRIKLARYGLEDDIKIINQKGVELAKRALQKAENKGYVIGTIGGIRSFQKSAFTLS
DIAENFREQLHVLLSENVDGIILETYYDLEELKTVLQIARKETDLPIITNVSLHEQGVFQ
NGTRLADGLKMLEELGADIVGLNCRLGPYHMLQSLEEVPLFEHAFLSAFPNGSLPRYENG
RLVYESDEHYFYEAALQFRKQGVRLLGGCCGTAPKHIRAMAEAVSNLPPVTEKEVKERNV
PIHVLPMKESQETPLPDIAKNRRSVIVELDPPKTLGLEKFLTGAKALKKAGIDAITLADN
SLATPRISNVACANIVKSRFQLRPLVHLTCRDRNLIGIQSHLMGLHTLGLHDILAVTGDP
SKIGDFPGATSVYDLSSFDLISLIKQFNEGLSYSGKSLGQKTNFTVAAAFNPNVRHLDRA
VQRLEKKISCGADYFITQPLYSEKLIEEVYEATKHLNVPIYLGIMPLISSRNAEFIHNEV
PGIKLSDSIREQMQKAGNDKEKGKREGLAIAKSLIDAAFDLFNGIYLITPFLHYEMTVEL
TEYIHEKEKAKRERKISHV
>A0A520Y0E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MKVTEHLERATDPFITFEIIPPTRGGKLSNLLGLIEDLMAHRPPFIDITSHAAEVVYEEV
ATGYEKRIKRKRPGTLGVCALVQNKFNIDAVPHILCEGFTRQETEDFLIELRYLEIDNVL
AIRGDSSGYEKRLEHGRSRNVYASDLITQIAEMNKGVYLEELLDASPTEFCIGAAGYPEK
HFEAPNLKADVARVKQKVDAGAEYIVTQMFFDNGYYFDFVDECRRQGIVVPIIPGIKILA
SQSQVVSIPRTFHCEVPAELADEVMNADESFASDIGVEWATRQTRDLLERGVPSVHFYVM
QSARLVNGVLANLDV
>A0A265AZ39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Heidelberg|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1I5P9F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas toyotomiensis|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLPR
>A0A6B4FGB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MNIKNLFKDKKVVFSFEIFPPKTTSSIQTIYDTLDDLKGLNPDYMSVTYGAGGSVKNNNT
IELSSLIKNKYGIEPVSHLTCINLTKKDVEYYLREFEKNNIENILALRGDVPIGSKITGE
LNHANELIKYISDNGKFNISAACYPEGHIEHKGLYREIESMKRKEEAGVSYFISQLFFDN
NLYYNFQDEVRAANINLPIEAGIMPVTNKKQIERILSLSGASLPDKFKRIMERYEHNPEA
LRDAGIAYAVEQIVDLISTGVDGIHLYIMNNPYVAKRISQSIESILLTVNQI
>B0NI34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium scindens (strain ATCC 35704 / DSM 5676 / VPI 13733 / 19)|TrEMBL
MKTTELFQNKSVLSFEVFPPKRTNPVDTIYKTIDSLKDLNPDFISVTYGAGGSENCKATL
EIASRIKNEYGIESVAHLPCISLTKSDVRRQLSDFKEAGIENILALRGDVPSCGYVPGDF
RHASDLIAFIKEHGDFNVLGACYPEGHQESADIFDDIKNLKTKVDAGASHLITQLFFDNH
YFYRFRERASLAGIQVPIEAGIMPVTNKKQIERMVSLCGVTLPHKFSAMMERYEHNPDAM
RDAGIAYAIDQIVDLITHGVDGIHLYTMNNPYIAARIYEAIHQLLAA
>A0A413ZNU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides stercoris|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEKNGYHHAVELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTNEILKCKNDAEAQQVGIEWCVQQCKELMKHHIPSIHF
YSIGAVDSIKEVAKQIY
>A0A1T3HBF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia anophelis|TrEMBL
MKVTEHIAQSKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGEKYFEPTKGGNRYASDLVTQINDLGKGKFLHGEISGNDTNNSFCIGVAG
YPEKHLEAPSMQYDLKMLKQKVELGADYVVTQMFLDNQKYFEFVKLAREAGIDVPIIPGI
KPFAVKKHLQLLPQVFKIDIPEDLVNAVSQCKNNEAVKQVGIEWCVQQCKELLDFGVPAL
HFYTMGKSDNIQKIVSEFF
>A0A1H4K9S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium coyleae|TrEMBL
MFEASPSTRLSASAPIDREGAPVIRRPRPKRQRTALSFEIIPPRPSDSVAKMDELIAGLA
AYNPDYVSVTSSRRSEWLEGTAAVISRIAETTDLRPIAHLACTAGTREELTEWIRTLIDA
GVRGFLALRGDLPETGMPEHYLQYATDLLNLIEEVQEEEAFRLAAGKLALSVACYPKGHE
ESRNFDHDLDVLLTKQRLGADFAITQLFFEAQDYLDFVEVARLAGVRIPLIPGIMPMTSL
KRVRRMGELSGLEVPEVVEKQLLEADDEYETGMQLTANLAREILDAGTGGLHVYTHNNLA
VTRDFLDRIGIQ
>A0A660HVM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina flavescens|TrEMBL
MLTNFREKLNSNKFLITAEVSPPKGTRFSVSLEDTRYLKGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDFPSCGDHPGSKP
VYDLDSVQLLQLVRKLDSGIDFAGNKLDGGTSFCAGAVTGIDPEKTIQLIKLEKKVRCGA
DFIQTQAVYDVGMFEEFMEVTNHLEVPVIAGLIPLKSLRMAEFMNKNISGISVPEEIMFR
IKDAPDPVEEGLSIASETIKELMRLSRGVHIMPVGSHKNTPRLLSMAGISGK
>A0A2K8N4E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kyrpidia spormannii|TrEMBL
MYNVHGLREKLALGKFVTTVELEPPKGADPLPTMEAAKFLRGKVDAVNIADSPMATLRMS
PIALAHIVQEDLGLEAIFHLTCRDRNLLGLQSELLGAAALGVRNILTLTGDSPSRGDHPE
VKGVFETDSIGLARLAERLNQGYDLTGHELSGPTRFLIGGVANPGAEDLDAEVAKLAAKV
EAGVRFVQTQPVFDIETALRFWERTRHLPVHILFGLLPLKSARQARYFNEKVPGVRVGED
VIQKVEEGGRAAGIALCRELYGGLREFAAGAHLFPIGDLRAVYEILDIDTDFRRAAI
>A0A6J6CHA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MKKIGEGVTYSFEFFPPKDPEGEERLWSAMGALEPIAPDFISVTYGAGGTTRDRTIRITS
EITQRTHIPTVAHLTCVGSTRDELIEILGRYKQAGIHNILALRGDPTGGPRAPWTPTPGG
LNHADELVTLAAEVGGFTIGVAAFPDGHPASGLDFAEDIEVLLRKEEAGASFATTQFFFE
ADKWKALVDRLAARGSKLPIIAGILPVSNVNQLNRMAELSGVPIPTSIADRFAALKESPE
DVKKLGVEIATQLCEDLLTAGVPGLHFYTMNTSSATREIFAQIKDKKRG
>A0A5P1DC28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas haemolytica|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTHYQQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A6J6K9G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVVGTSYSFEFFPPKDIEGEGRLWHAIEGLKSIAPDFVSVTYGAGGSTRDRSIRIAREIT
NRTGIPTVAHITCVGSTRNELLEILNSYKDAKITSILALRGDPTGGPLAPWLPTENGFNH
ADELVELAKECGGFKIGVAAFPDGHPSSGGDFEKDIDVLIRKEKLGATFATTQFFFDVKA
YKNLVERLAKRGSALTIIPGILPVTNVKLLHRMAELGGTPIPDHIAKAFAEVESDSQAVR
ELGVEIATKLCKELLEAGAPGLHFYTMNSSTATVEIYRRINNVN
>A0A653FKY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium smegmatis|TrEMBL
MTPSGADPQVPVCPKRMTYGPCGGVRPDGRCEMRSGPCIFDDLVPWGGPVATRPPVRAPL
VLTDFSCAPFDEQDVVRTAGVLAGSCDAVLVGEHQNKPDFPPTLMGRLLLDALTGSGVTP
WITLSCRDRNRVVLEQELRGLRSIGADTVMCVTGDGRGYDVRPDVTQTFDLDGPRLVALA
ASLDMVAAVPETPTAPPVNARPRRLVEKQKAGAGIAVLNHVPYPHTVARFMESGRAAGLT
IPVIAAVAVFTDTASAAVLQGLPGLELDPAVTQRVLGAADPVEAGIEAAVEEARALLSID
GIEGVNISGSASASGGGAAIKAEVGRRVKNLCVDRTRGEAP
>A0A6J7XWD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSLLREKLENSKDLVFTAEFPSVDGGGMASVEKNVARLAPWFDAVNATDNPAAHAHASNT
TTAIAMKMHGLEPIMQIVCRDKNRIAIQADMMGASLHGITNLSLLTGDDVTAGDEHEARR
VFDIDSAQAINIARVMATGTYLSGRAIKPAPDFYIGAVENSAAPPFDYRIQRALKKHRAG
AKFLQLQICYHPDRLEAFCKGVAEIAPDLKLIPTIVIVKGAKPLGFMHDKVPGIDVPSQT
LARVQNASDQSEEVYSLTLELAQHALSLPGVRGLHITDFRHDDSLARFMSDLGRTPRN
>A0A5X9XFD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Worthington|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3S3LZT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A529UMH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MTARQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAQRLDHILHDEITETQVDMVK
TAH
>A0A2Y9C440|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalicatena orotica|TrEMBL
MKIIDRLKEDRIHISFEVFPPKTDAGVDNVMRATDRIAELRPDFISVTYGAGGGTSRNTA
KIAKHIKEDLGVESLAHLTCASSTKDEVRGVISNLKELGIENILALRGDIPADQPFPTED
RFHYAYELVEEIRRSGDFCIGAACYPEGHVENEHKEDDIKFLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAKQMKRSLELSGTVFPRRFQAILDRFGDYPN
AMEQAGIAYATDQIIDLLANGVKNIHIYSMNKPETAEAIMRNLSEIIKC
>N1QRS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aegilops tauschii|TrEMBL
MKVIEKIQEAAANGRTVFSFEYFPPKTEEGVENLFERMDRMVAHGPNFCDITWGAGGSTA
DVTLDIANRMQNMVCVETMMHLTCTNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFSCALDLVEHIKAKYGDYFGITVAGYPEAHPEVILGEEGATEEAYSKDLAYLK
RKVDAGADVIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNL
GLIEESKLSRTLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWGDSRNP
SYGALNDHQFTRPRGRGKKLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPE
TTIIDDQLVKINSKGFLTINSQPAVNAEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLG
QLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWSRGWACLFPEGDSSRELLEQIQKSYYLVSLVDNDYISGDLFAAFKEI
>V5AAJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon A07HR60|TrEMBL
MSSTSSVPQTGPAAGGLLAEPRFELMPFDSMEGQLDHLPDGATVAITASPSLGLDATVDW
SVQAAEQGYEVVPHVAARYVEDDEHLDEVLSRLAEAGVTDVFIPGGDREEAIGEFESSHD
LLTAMDRLGHEFDDVGITGYPEGHDFISDETLADVMDKKAPYATYVTTQLCYDPETILRW
IETIRDRGIDLPVEIGIPGVMKYQKLLKISRKVGVGDSIRFLQKTSGITGFIKQFIRSRG
KFSPDELVDELDPYYQDAEYNLRGLHVYSFNQVPDTETWREDRLNN
>A0A7S3M0H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spumella elongata|TrEMBL
SKLVTFSFTMDLSPKISDILAAKPKDEVAISVEFFPPKTEAGVTSLYNLAEKMKAFNPKF
ADVTWGAGGTTSDLTLELCANLKAKSGLNPNMHLTCTNMEKQKVVDALKGCKEVGITNIV
ALRGDPPAGQAAWEAVEGGFNCALDLVKFIRQEHGDYFCLSVAGYPEGHPNRMSTVADIS
ELTETEKARCAILSNEAGEDIITVCKDEDFEKELDYLKEKVDAGADAIITQLFFDVEVFT
TFVTRCREKGIKVPIIPGIMCVASAGGFQRMVRFCKTRVPQGLMDQAKAISEDAEMKVLG
IAYGTQMCL
>A0A1S3V6X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vigna radiata var. radiata|TrEMBL
MKIIEKIRDATADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANRMQNIVCVETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVKHIRAKYGDYFGITVAGYPEAHPDVIGSDGLATAEGYQKDLEYL
KSKFDAGADVIVTQLFYDTDTFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPADIMSALEPIKDNEEAVKSYGVHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALTDYQFMRPRARDKKLIEEWVVPLKSVEDIYERFRMYCIGKLRTNPWSELDGLQP
ETKIINEQLERINAKGFLTINSQPAVNGEKSDSPTVGGCKGSLFLFMHDIFWSYVYSILV
CTSYRKMPNFLIQVR
>A0A7V2TNX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
LIPTVMLLKSLGMVRYIRSNLPHIYIPEEILDRIAAAPDKVRECVQISAEMIRRLKEQGY
GGVYLATLGWEHRLPDIVENL
>A0A7C1CM98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MRPLRALYASGKPVISFELFPPKTEAGMNNLFTHLEELANCRPAYFTCTYGAGGSTRNRT
LLVLREIRERYPHIPVASHLSCIGSSRGELRQYIRAAIEIGVDRIVALRGDRPQDQEVFE
PAPDGLRYANELVELIRREFPELGIIVAGYPETHPEAPSSAADLDNLKRKVDAGADVVIT
QLFFENTDYFRFRERCEDIGINVPIVPGILPVTNLTQIRRITSLCGTHLSPKLVRRLEVH
GDDDEGQYAVGVYYAAKQAEELIAQGAPGIHFYVLNKSRAAALICRALALFTPVD
>A0A543KAY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseinatronobacter monicus|TrEMBL
MSAPRVSFEFFPPKTLDASFRLWDTVRMLAPLSPSFVSVTYGAGGTTRQLTHEAVTTIGA
QFGLNVAAHLTCVDATRAETLAIADSYTKAGVTEIVALRGDPPKGQGRFTPNPDGFAHSV
ELIEALAETGNFNLRVGAYPEPHPEAADELADVRWLKRKFAAGADSAITQFFFEADTFLR
FRDTCAREGITGRIIPGIIPIENWSGIRKFALAAGTTVPAWLDDAFEKATRDGREELLAT
ALCTELCDKLVREGVEDLHFYTLNRPHLTRDVCHALGVQPHVSLEKVA
>A0A5C3EX97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudozyma flocculosa|TrEMBL
MSTPIASSPPSPPPKGDASWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERM
AELGPEFVDITWNAGGRTSDLTSQLVKTVHTYIGLETCMHLTCTNMPREKVDTALREAKE
FGCRNILALRGDPPAGQSEWEPHAAGFTYAHELVEYIRENYGDYFAIAVAGFPEGHPEAT
EGKELEMQRLKAKIDAGADFIFTQMFYDFDIFAQWVKDVRAAGITCPIVPGVMPIQTYGG
FQRATARFRTMVPQYFHDALDPVKDDDQKVREVGLKLVGDMCRKIVGSGLGISGLHIYTM
NLEKGSRMLLEYLGLTPSVNQVSPLPWTPSLTPKRREEKIRPIFWANRAKSYVNRTETWD
EFPNGRWGDARSPAYGDFDAYGVKLRYSPDEALQLWGTPTSLDDVKQLFVSFCAGKVKAL
PWSETGIAKETSVIDTKLARMNQLGYLTINSQPAVDGARSDDKVHGWGPKGGYCYQKAYL
EFFVAPDQLEALISRIELDPQVTYHAVNAQGDMKTNVNSEAPNAVTWGVFPHCEIIQPTI
VESISFLAWKDEAYEIGRNWARIYPAGSESRRLLDSIFDTYFLVNVVHNDFKAADAIFQP
FLEGQAQAQSSGQGVGGIVSSTLKEAANGVKNGIDGALSRLTTADGSAPAVNGA
>A0A4Q3IUE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MSSGSGSASLNPSESISALLRRGWRSFSFEFFPPKDEAGEEVLWRSIQDLEDLRPTFVSV
TYGAGGTNRDRALAVTERIARETTMLPMAHL
>A0A0S8IM67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium SM23_72|TrEMBL
MTFKEKILAGQFLLTSEIGPPKGIETGQLLEDAELIRSRVDAINVTDLQSSVMRLGSLAV
CSLLKQRGFEPIFQVTCRDRNRLALQSDILSAAALGIENLLILTGDHTTMGDHPEAKPVF
DLDSVQLLGVVRKLQEGLDMKGNKLEGRAPKFCVGAVVNPGADPIEPQIIKMEQKIEAGA
EFFQTQAIYNVKIFENFLNKIKHLKTTILAGIVLLKSAGMAKYMNKNVAGVTVPDNLIKE
MEETKDKSAKSVEIAARLIKELKPMCQGIHIMPIGWDKKVPLVLDAAGL
>A0A3M1IGX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MVLDETVFEKFYKEVLNEYGHSFPILPGIRVPSSSKQLKRMKDKFGIRVSKKLMKEMIAA
EEAGKNPKEIGIRWAVEFTQFVRKLGIRGVHFFIMNDVESAILVKKRLSF
>A0A259MU39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium 39-66-50|TrEMBL
MSPDTGPIGNPLSSPGSATEFPARAPQRLAVSFEFSPPRTDAAEQTLWETVKRLTPLHPS
FFSVTYGAGGSTRQRTHDTVARLKSETGIDAAAHLTCVAATQGEIDDIARAYWDAGIRHI
VALRGDPPGGMGGQYTPHPGGYANAAALVAGLKKIGNFQISVAGYPEKHPASADEKADLE
NLKAKVDAGADRCITQFFFEAEDFLRFRDRAAAMGINVPIVPGIMPVSNFQSVNRIAGLC
GSKVPPWFCNMFDGLDDDLETRRMIAATVAGDLCRRLRDEGVEQFHFYTLNRADLTFAIC
HLLGVRPK
>A0A1M5PR98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium granuli|TrEMBL
MKVTEHIENAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVE
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGINN
VMALRGDAMKDEQSFVAKEGGNNFAIDLVQQINKLNDGKYLHDVMHVDNKADFCIGVAGY
PEKHLESPSLLSDLKRLKEKVDAGADYVVTQMFFDNEKYFQFVAKAREMGITVPIIPGIK
PLAVQRHLQILPQIFRIDLPEDLIHAVDQCKNNTEIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASRVF
>A0A2D9HAR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MRVIEHLDRAKEPLISFEIIPPRRGGDLKSLLGLIDDLVAHRPPFIDITSHPAVLSYEEG
PDGIRKVIKRKRPGTLGVCALIQHKYNVDAVPHVLCRGFTREETEDFLIELHYLGIDNVL
IIRGDDNGYMKPVKEGRTANRFAVDLVSQVGDMNQGQFLEPYLQALPTNFCVGVAGYPEK
HMEAANLDMDVRRLREKVEAGADYIVTQMFFENAHYFRFVEKCRDHGITVPIIPGLKVMT
VKKHLTSLPRIFNCEIPTALADEVETADKDKILEIGAEWTANQAQELLDSGVPSVHFYVM
QSSKAINKVLKRLKR
>A0A2M7M7Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piscirickettsiaceae bacterium CG_4_10_14_3_um_filter_44_349|TrEMBL
PGIMPITNYENLIRFSEGCGAEVPRWLKCRLESYGDDTESLKAFGQEVVTEMCQRLLDAG
APGLHFYSMNQAEPTTSIVQALTFKSPLE
>A0A257JXF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. BFFFF1|TrEMBL
MKVTQHIENAQGKSLFSFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYEFKE
LENGLLEKKVVKKRPGTVGICAAIQNKYSVDAIPHILCGGFTKEDTENFLIDIDFLGIQN
VVALRGDAIKSEIYFRPEKEGHQYASELVTQIDNLNKGIYLDPELQNSAQTDFCIGVAGY
PEKHMEAPSPDSDIYFLKQKIKNGAEYIITQMFFDNKKFFDFVAKCRAEGITVPIIPGLK
PIVTKKQLNLIPHRFKVDLPDDLIMSIVKAKDNDAVREIGIEWCIQQSRELLAAGIPVVH
YYSMGKAANIKAIAKEVF
>A0A1E4CDK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. SCN 69-37|TrEMBL
MALKWGIEAGADRPHDPDPRGNRAKMAHEPRVGAPAAAVTASPRVPFSFEIYPPRTPEQL
PALYETIRVLAAAGPRFISVTFGAGGSTTDRSLTVLTHILRETTVPPVAHVTCVGSSYAE
ATTVIRDFLDAGITRFLALRGDPPVGIGEDDIVFGDLESAAQLVQLIGRVQAERSPYRER
EIPGLPGAVQVTDGDRVQIAVAAFPNGHPRSRHRYEDIDALLAKQAAGATSALTQLFFHA
DEYLDFVERARAAGVVIPIVPGIMPITSPGRLRRVLELTGDARPDALAAALESAPDAAAQ
RAVGLAHAADLARSVVAGGADGIHLYAFNNHDTVLGVLRAAELISEASP
>U9XV21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 113290|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2P1QYS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira santarosai|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSHLDPDFVTVTYGAGGSTRSK
TAQILSEISKNYSFPTVSHFTCVGANQEQILKTLKEIRSSGIVNLMALRGDPPKGEGQFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPNAKNLEEDVENLKRKVDAGADFLVS
QLFFVNSIFENFLNLVGKVGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKN
>A0A1X1NKU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB03238|TrEMBL
MALGTPSTRTDRARTVRDLLATGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATQEIAADTTLTPVAHLTAVNHTIAELRNMIGQYADADIRNILAVR
GDPPGDPMGEWVPHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVD
KCRAGADYAITQMFFFPEDYLRLRDRAAAKGCDTPIIPEIMPVTSVKQIERFAQLSNAHF
PPELKERILAVKDDPAAVRSIGIEYATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHEQS
>A0A7S0WC20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hemiselmis tepida|TrEMBL
RVCDLIAERAAGGGAEAFYALEFFPPNTPEGARNLISRVDRFGQAPSPPLWVDVTWCLDS
GKRAMETLVAAKAVCGLAVQLHLSCTGLTRDMADGVLEDCVEARIFSLMILRGDPQPPGS
EWECPHDGFPRARDLVAYIRRKHGDTFSIAVAGHPGGLPGGGGLDAAVHNVRDKVDAGAD
YVVCQVGFDASEYASLV
>A0A6G8Q2R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacter marinus|TrEMBL
MEHPRYELVPVEGAREQAIYLPAGAEVSVTCSPTLGIGSTIALAEELLARGFPVVPHLAA
RLIEDETRLKAVLGRLEERGLKDVFVVGGDSKVPAGPYASGLTLLRAMSRLGAGIERVGV
PAYPEGHPLVAEEELTRALLAKQPFASYAVTQICFEPETVLGWLARAREGGLKLPVYVGV
PGVVDRKKLLRISLKIGLGDSMRFLKKQTGLVGRLLRPRGYSPDALIEGLSPYVGDPDYG
IRGFHVNTFNHVEETERWRRGRLGSTADGGVFEGVRRAAPAPMQGKE
>A0A8D6C619|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium modestum|TrEMBL
MQSQTPTIADLLASGERPLHSFEFMPPRSEDDVYRLWSATDALVPMAPDFISVTYGANGS
RRDRTLRCTQHMVSTGLRTVGHLTCVAQSVADLEQMVADYAESGVDHVLAIRGDMPGGAG
LPWVPHPEGLPNATELVRLVKRIHPEACIGVGAFPDGHPEARDIDLDARILVDKAQAGAS
FAITQLFFLPSHYQRLVERVRGMGCDIPITPGIMPITSYGQIRRFSELAGTDVPAELVAQ
LEEAKGDKAAVRRIGLAAAVDMCCELLDAGAPGLHYYTLNRSRATTELRTMLAQRRPELA
GLPREFEVSSAV
>A0KQ32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)|TrEMBL
MGFHSARQVEALNQSLADLSGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPEMYATDLVALLKAEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDDDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQP
>A0A3A6U8F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parashewanella spongiae|TrEMBL
MSYHAQHSNTLNQGLSELKGDINVSFEFFPPSTPEMEKTLWKSVRRLEPLNPKFVSVTYG
ANSGVRDRTHSVIERIQQETKLTAAPHLTLIDACDDDLKLIAAQYWSSGVKDIVALRGDV
PAGEASPQRYAADLVSLLRSVADFDISVAAYPETHPEAKNAQSDLINLKRKVDAGANRAI
TQFFFDIETYLRFRDRCVATGIEAEIVPGILPVTNFTQLKRFANQTNVTLPNWLHQQFSG
LENDAETRQLVGANVAIDMVKVLAREGVKDFHFYTLNRAELTYAICHTLGVRGEA
>A0A1H1AHV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas sp. CF385|TrEMBL
MPAISFEFYPPKTDEQRAQLDRTADKLKAHAPDYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGSREEIRELLRLYRALGCKRIVALRGDLPSGMGHPGDLRYASELIEFI
RAEHGDTFHIEVGAYPETHPQAEDAMTDLRHFKAKVDAGADGAITQYFYNPDAYFHFVDA
SRKLGVEIPIIPGIMPISNFAQLRRFSEACGAEIPRWIGKRMQALGDDADAIRDFGADVV
AGLCERLVAGGAPALHFYTLNLAKPTQTVLARLGWAD
>A0A291Q6N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces formicae|TrEMBL
MLATGKTTFSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSVTYGAGGSTRTGTVKETQQ
IVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPLGDWIAHPEGL
TYAAELVELIKESGDFCVGVAAFPAMHPRSPDWESDTRHFIDKCRAGADYAITQMFFDPE
EYLRLRDRVEAAGCHTPIIPEMMPVTNVRQLERLPQLSNAVVPAELKERILSVKDDPAAV
RSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHQA
>A0A433UT46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix desertica PCC 7102|TrEMBL
MLIVMLDTLTPITPVKVSSFRAAARNGEFLVTAEVCPPKGGNPQHMLQMAATLKGRVHAV
NITDGSRAVLRMSPLVASAILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIQNILAL
TGDPVKAGDHPDCKAVFDLEAVRLLQVIQKLNLGVDYNDKPLTDGALDLFVGAAVDPQCK
SWSGLQSRFEKKVEAGAQFFQSQLITDFERLEKFMDTIAAGCNKPILAGIFLLKSAKNAE
FINRVVPGVNIPQHIIDRLAQAKDPLSEGVKIAAEQVQIARQLCQGVHMMAVKREDLIAP
ILDMAGVKPVSMVVAK
>G4SUH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotuvimicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z)|TrEMBL
MQTQQKYPKLFSFEFYPPKTEAGEESLQAVHKKLSRLNPDFFSVTFGAGGSTRDKTFDTV
VKIQERGVAAAPHLSCVASTHENIREILHGYRSNGIKKIVALRGDLPSGMMSAGQFRYAN
ELVDFIRSETGDYFQIHVAAYPETHPQARSAAEDLKNFKRKVDAGANAAITQYFYNAESY
FYFVDACEKMGIDIPIVPGIMPITNYSQLFRFSDMCGADIPRWLRKKLEGFGDDREQIIA
FGCDVVTRLCQQLLDNGAPGLHFYTMNQSAPTLAIWNNLNLSD
>A0A5C7RSF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus sp|TrEMBL
MTERTFSFEFFPPKTTEGAEKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETVCDIQA
SGSEAAPHLSCIGSTEASIRDILNAYKSQGIRHLVALRGDLPSGTMDAGEFNYANELVAF
IRKETGDWFEIEVAAYPEVHPQARSATEDLANFKRKVDAGANSAITQYFFNADAYFNFVE
DARALGVAIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLASIRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPSTTIWQRLGL
>A0A502IJY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mandelii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWKNLKLPR
>A0A1H3PIW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jannaschia faecimaris|TrEMBL
MPVPSVSFEFFPPKSLEGSFRLWDCVNTLAPLAPEWVSVTYGAGGTTRELTREAVGALGK
QFNLRVAGHLTCVDASREETLEVARGFRRAGVEDIVALRGDPPKGATGFTPHPDGFKTSI
ELVGALADQGFTVRVGAYPDKHPEAADAQADIDWLKAKIDAGASEAITQFFFDAETFLRF
RDRCAKAGIDAPIVPGLLPIENWAKASKFADACGAVIPDDLRAAFDVAERDGRTDLLAIA
QAAELADALTVEGCDHLHFYTLNRPELTRDVCLALGLAARKALSRVA
>A0A1E8PRS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium lividum|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRTKLSQLQPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVSRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGEHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTALCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A525CZX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MSFQKRLFAQEFVVLAEMHTPKGVNITRLVNDARRIKGRVDAVVIPDMDNGIMRMSALAG
GALMLQHGVEPIIHLYARDRNRMALQGDALAAHVMGISNLLVTHSEGMDQSDHREAKEVF
DIDELELVQALNGLNQGKDMGGFELDGTPDFTVGCTIGSFGDEAALDQELIAAQAKVEAG
ARFIISPPVFDLEKFQSFMAKVKPLSVPVIPTVFLIKSLAIAQYIAASEPEAGISNELIR
RIRKSSDRELEGIKIAGETLAGVREMAQGVMLQTLGWEHKLVDILDAAGM
>A0A3A6MVE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ammonifex sp|TrEMBL
MIKEFFNYRRPVVSFEIFPPKTEDRMEIVSRLASQFKELNPSFISVTYGAGGTTRDTTIE
VATYLSRLGFEVMAHLTGVGHTAGEIDDILSRLKAGGVDDILALRGDPPKGVENFDYAAG
DFKFAVDLVRHIRRRGGFGVAAAAYPEGHIASPRIKLDWMHLKEKVDAGVDFLITQLYFD
NRVFYNFLDSVRRLGIACPISAGILPVLSADALKRMVTLCGAAIPAKLWDIIDKYADDHE
SLEKAGIEYATAQVHDLVEYGVDGVHLYTLNRAEWVAAVLKDTGLDRYEHLPEAWEWQQV
QYGELPPGGRNPAVWQVVERRDL
>A0A5E4TLT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea aquatica|TrEMBL
MNGTHDNKTIMTQPSFSFEFFPPKTADGAEKLRATREQLFPLGPKFVSVTFGAGGSTQQG
TLDTVIEIQREGVDAAPHLSCVGSTRDNIRDILTTYRNNGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGDWFHIEVAAYPEYHPQAKSPRHDLEHFANKVKAGANAAITQYFF
NADAYFRFVDDVARLGVDVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
EAIRAFGLDVVSALCERLLKEGAPGLHFYTLNAAAATKAMWQRLGL
>A0A377RK80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium lividum|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVKRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGANAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQATPTTALWQRLVK
>A0A6J1ZFS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinonyx jubatus|TrEMBL
MVIASTAVNYCGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEE
GGFSYAADLVRHIRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQL
FFEADTFFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKD
NDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPW
AVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLT
SKSPREELLKMWGEELTGEESVFEVFACYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKE
ELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVL
KKYELRVNYHIVDVKGEKITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFA
LWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPGPE
QETETL
>A0A1S2QPS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. MUM 13|TrEMBL
MDFRNELKKRVLIGEGAMGTLLYSHGIDHCYEELNSTDPGQIETIHRAYLEAGADILQSN
TYGANYHKLKRYGLEDEVSAINRNGVAIARKASEGKAFVFGTIGALRSIRKNDLSMEEIK
RSFREQLYSILMEGPDGLILETFYDLEELETVLPIARKETDLPIISNVTLHEIGYMQNGI
HLNEAFQRMEQLGADVAGINCRLGPHHMIRSLEEVPLMKNTPISVYPNASLPEYIDGRLI
YEAVPEYFGSSALKLREQGAAVIGGCCGTTPLHIAEVKKKLGIIPPVTQKEIKARKIEII
EIIDDKTPALHQLAKRKRTVLVELDPPKKLGIEPFMMGAKALLDAGADSVTLADNSLATP
RISNAALGVMLKNQMGANPLIHLTCRDRNLIGLQSHLMGLQTLGLNELLVVTGDPSKIGD
FPGATSVYDLSSFDLISLVKQFNEGLSFSGQSLGQQSHFKIAAAFNPNVKYLDKAVQRME
KKITCGAQSFLTQPIYSVNQMEEVYEATKHLDTPVFAGIMPLTSARNAEFIHNEIPGITL
PDDVRRAMAAAGSNPLLARNEGLAIAKSLADAAMEKFQGIYLITPFMRYEMTVVLTEHIR
KTDSMKLAGVTAYE
>A0A7J8F9V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Molossus molossus|TrEMBL
MVNEPRGNGGPNPRSEGIGSSKGISGCSSPGLDPKRHERLREKMKRRMESGDKWFSLEFF
PPRNTQGAGSLISEFDQMGAGGPLFIDVTWRPTGDPGSDKETSSMTIASTAVHYCGLETM
LHMTCCCQSQEEITGHLRKAKQLGLKNILALRGDPLGDHWEEEEGGFHYAVDLVKHIRKE
FGDYFDICVAGYPAGHPDAESFAADLKYLKEKVLAGADFIITQLFFEADTFFRFLKACSE
IGITCPILPGIFPIQLVKLSKLEVPQRIKDVIEPIKGDDEAICNYGIELAVGLCRELLAS
GLVPGLHFYTLNRRMATTEVLKRLGMWAEGPRRPLPWAVSAHPKRWEESVRPIFWASRPK
SYIYRTQEWDEFPSGRWGSSSSPAFGELKDYHLFYLRSKAPRGQLLKMWGEELTSEESVF
DVFVHYLSGEPNQNGCRVTCLPWNDEPLAAETSLMKEELLRANRRGILTINSQPNVNGKP
SSDPVVGWGPSGGYVFQKAYLEFFTSRKTVEALLQVLKKYESRVTYHIVDVKGENITNAP
ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFTLWAEQWGKLYDEESPSRMIIQDI
HDNYFLINLVDNEFPLDNCLWQVVEDTFELLNRPTSQ
>A0A832A457|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfacinum infernum|TrEMBL
MKAGSNLEKIFTQGHFAVTGELGPPRGASVEVIEKKASHLRGVVDSINVTDNQTSVVRMS
SVAVCKLLVDMGLEPNLQMVCRDRNRIAMQSDLLGAYALGIRNVLCLSGDHNRFGDHPQA
KNVFDVDSMQLITIVKKLRDEGKMLSGQELEGVPKFFIGAAANPFGDPFEFRVTRLAKKI
DAGVDFIQTQCIYNMEKFRKYMHIAHEEGLTEKCYIMAGITPLKSVGMARYMANFVPGLD
VPDYYIERLKGVDKKKQADEGIKIAVEQIQEVREIPGVKGIHLMAIEWEHKVPEILEAAG
LLPRPSVN
>A0A8H5QQN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium tjaetaba|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLSRLDAVKGDDERVKMVGVDIVSELVDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKARLTSPELQDSVCFYASNARGDYLSSDSSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A6P0SQL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO2I5|TrEMBL
MTNPTKNSFRTAVESGEFLITAEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQQGIEPICQVACRDRNRIALQADLMGINALGIGNVLALTGDPVKVGDHP
DAKSVFDLGSVGLLQLITKLNQGVDFNDKPLT
>C0EQM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria flavescens NRL30031/H210|TrEMBL
MNHAREINALNHSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHSIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVMMGIDVEIVPGILPVTNFKQLAKMAQVTNVKIPSWLSKMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRPR
>A0A2K6RU63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhinopithecus roxellana|TrEMBL
MVNEARGNGSPNPCLEGSASSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSIMIASTAVNYC
GLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDLCVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTNMGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIERWGKLYE
EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNERETETP
>A0A7H1QVQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peribacillus butanolivorans|TrEMBL
MDFRKELKERMMVGEGAMGTLLYSYGIDQCYEELNCTNPDQIESIHRAYLEAGADILQSN
TYGANFNKLKRHGLEDEVSRINRQGVILAKKAAKGNAFVFGTIGAQRSIRKSDLSMEEIK
RGFREQLYSLLIENPDGILLETFYDLEELETVLQIAKKETELPIIANVSMHELGNLQNGI
HLNEAFQKLEQLGADVVGVNCRLGPHHMIRALEEVTLPKHAAIAIYPNASLPDYVDGRLV
YKAVPEYFGSSALELREQGATIIGGCCGTTPLHIQSVKNAIGSLVPVEEKMTKAREIEII
EVNHRELELPLHEQAKTERTILVELDPPKKLGIEGFMAGAEALKNAGVDSITLADNSLAS
PRISNEALANLLKNQLDVNPMVHITCRDRNLIGLQSHLMGLQTVGLNEILIITGDPSKIG
DFPGATSVYDLSSFDLISMVKQFNEGLSYSGQSLGQRANFKIAAAFNPNVKYLNKAVQRM
EKKIACGAQSFLTQPIYSVDQIEEVYEATKHIDTPIFVGIMPLTSTRNAEFIHNEIPGIK
LPDNVRRAMALAGDDPIKSRMEGVNIARELVDAAREKFNGIYLITPFLRYEMTAELTKYI
REVDSKHTSEVAVHE
>A0A7V7ZI45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexia bacterium SDU3-3|TrEMBL
MAIYSTLQRRLAQGQIVVTGEVAPPKGASRAALERLAGGLRGYVDAINLTDNQRGLARMS
SLGAGVVMQQIGMEPVMQMTCQHRNRIALQADALSAAVCGIHNLVCMTGDHPRIGDHAEA
KNVLDLNSFQLIKMMRSLRDDGAFQSGVKLSDAPGFFLGAVANPNIERAARLAKKVESGA
EFIQTQIIFDMERFRSWMTDVRAVSAHQQAHILGGILVLRSAQQAKFLRDHLPGSRVPEW
VVERMEQAEDAEREGIAIASELTRDLLAVDGVRGVHIMSVGWTKAIPRVVEDAGLLPRPA
APAGAGE
>A0A1Q8DJH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. C 20.9|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALSA
RSETEIAPHMSCIGDDKAQIAELLEFYKSLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFEFDVDNLVNKYRAGANASITQFFYNADSYLYLR
DTLEKRGIDTIAQPLVAGIMPITNSSNLIRFADSCGADIPRYVRKRLADFGDDSKSIREF
GFDVVYRLCERLMSEGVPAMHFYSMNKVEPNKRLVEALGLTV
>A0A2R3EWJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. WE21|TrEMBL
MAFHHAQHSQSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPNWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A2N3DSA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HGW-Alphaproteobacteria-13|TrEMBL
MTTSLNAAAEARRAAASPLFANLDGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLGPRFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASRAEIDEVARAYWDAGVRHIVA
LRGDMPGGAPYRAHPDGYANAVELVAGLKAIAPFDISVAAYPEVHPDAGCAEADLDNLKR
KLDAGATRAITQFFFSPDAFLRFRDAAAAAGIDTPIIPGILPVSNVSQTRRMADMCGTAI
PAWMAGLFEGLDDLPAARQLVAATIAAELCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPAAAPATTEKAA
>A0A0X8HAQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas chromatireducens|TrEMBL
MSTQAHPLGISYEFFPPNTDLGREKLMGVRDALAERNPRFFSVTYGAGGSTQARTLNTVQ
TVRESGITTAPHLSCIGSEKAQLRDLLHRYREQGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFEKDLENFVRKMQAGANLAVTQYFFTADAYF
HFVDRARSLGVEAPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSASIAAF
GEEVVSRLCQRLLDGGAPGLHFYTLNQAAPCLRILDNLS
>A0A151KYX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cidicii|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSTPQMEETLWSSVQRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAQTGLVAAPHLTCIDASRDELINIANDYWANGIKNIVALRGD
IPPGGGAPEMYASDLVTLLKSLHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDDDPVTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKQA
>A0A8G4KUG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVAPKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A7Y8LEE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MTFREAINSGKFVVTAEIGPPKGTDIHEMLHHIELLKGKIDAANVTDNQSAVMRICSMAV
CKIAIEHGLEPIFQMTCRDRNRIGLQSDLLGAHILGIKNVLCMTGDHVTAGDHKNAKPVY
DVESVQLLQIVDSLNHGKDMAGNDLKGATDFYQGAVVTPEATPLEPQLLKFEKKINAGAN
FFQTQAIYDIERFKEFMKFARRFPVKILAGFVILKSAGMASFLNKNVPGIRVPQELIDEL
KAAGKEKALDAGLNIAARHIRQLKEENICDGVHIMAIGMEDKVPIIMERAGLL
>A0A8C0ART9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buteo japonicus|TrEMBL
RELTMVNETQHTCSASSSSKSDGGSSSGGESSKDSSRCSTPVLDADRHERLREKMRRRQE
SGDKWFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIAN
TAVNYCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNY
AVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRYLKEKVFAGADFIITQLFFRSE
TFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAI
RNFGVEQAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWAVSAH
PKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPR
EELLKMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKV
NRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYEL
RVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQ
WAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNTQTQ
>A0A7V4X6T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MTFKDKLQAGKFLVTSEIGPPKGIETKQILEDAELVRGRVDAINVTDLQSSVMRLGSLAV
CSLLKQHGLEPIFQVTCRDRNRLALQSDILSAAALGIENLLILTGDHPTLGDHPEAKPVF
DLDSVQLLGVVQKLQQGTDMNGNKLSGTAPKFCVGAVVNPGADPIEPQIIKMEKKIEAGA
EFFQTQAIYDIGIFENFLNKIKHLKTTILGGIVLLKSAGMARYMNKNVAGVSVPDSLIKE
MEEAKDKVAKSVEIASRLIKELKPLCQGVHIMPIGWDKVVPRVLDASGL
>A0A7X8ESB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epulopiscium sp|TrEMBL
MHTSELFKTKRVLSFEIFPPKRTGSINTIYDTVDELKELNPDFISVTYGAGGSKSNSDTL
KIASDIKNKYGIESVAHLPCINLTKKDVLEIMGHLEDAKVENILALRGDTNPNITPKNEF
KYASDLISFIKGNSNFNIIAACYPEGHIESPTVVEDIHNLKVKVDAGVNQLITQLFFDNE
YFYSFLERINIAGINVPIQAGIMPVVNKKQIERMVTLCGVNLPKKFLSIMNKYENNPKAL
RDAGIAYAIDQIVDLIAQGVDGIHLYTMNNPYIAHRIYEAIHTLVVS
>A0A1V4KP23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Patagioenas fasciata monilis|TrEMBL
MSEKGNREAPPLDTGGRELTMVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLD
ADRHERLREKMRRRLDSGDRWFSLEFFPPRTANAAVNLISRFDRMAAGGPLFVDVTWHPA
GDPASDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDITANLQKAKRLGLKNIMALRG
DPVGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDVCVAGYPKGHPEAESYEADLRHLKEKV
LAGADFIITQLFFRSETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQ
EIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGM
WNEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFG
ELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDD
PLATETNLLKDQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTS
SEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPV
SFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDD
TFELLNSPTQK
>A0A0M2HXZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hydrocarbonoxydans|TrEMBL
MSSETLNPRVPFSFELYPPRSESSQAALHETVRRLAAAGPDFISVTYGAGGSTGGRSLEV
LRFIREHTDVEPLAHITCVGNTYAGAAALIREFLDAGILSFLALRGDPPAGHDEPFLGDL
ESAAQLVQLIDRVQAERSPYEEAPVPGLPGAATVGARRKATVAVAAFPNGHPRSTHRWQD
IDALLAKQAAGASSAITQLFFHSDDYLSFVEKARAEGVTIPILPGIMPIVSPVRLARVLE
LTGETLPSELSIALDVEPTPEGRHEIGVEWAARLAREVVAGGAPGIHLYAFNQHHTVLTV
LEEAGVLPAARMR
>A0A0C1QSY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolypothrix bouteillei VB521301|TrEMBL
MHNILTTTPLSSFRAAAQAGEFLVTAEVAPPKGGDPTHMIEMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQNGIEPICQIACRDRNRIGLQADLMGAHALGIHNILALTGDPVKA
GDHPEAKGVFDLESIRLLQMIQKLNHGVDCNEQPLTDGALNLFPGAAVDPQCNSWSGLQS
RFDRKLEAGAQFFQSQLITDFERLEKFMDQIAGGCNKPILAGIFLLKSAKNAQFINRCVP
GVNIPQDIIDRLAKAKKPLEEGMKIAAEQVQVARQLCHGVHMMAVKREDLIPQILDLAGV
APVNLVVSK
>A0A411H2F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edwardsiella piscicida|TrEMBL
MSFFHASQHDALNQSLAELQGRIQVSFEFFPPRSQEMEQTLWRSIDRLSTLRPSFISVTY
GANSGERDRTHGVIKGIKERTGLEAAPHLTCVDVSREALRGIARDYWNSGIRHIVALRGD
LPAEGGRPEMYASDLVALLREEADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGASRA
ITQFFFDVESYLRFRDRCAAAGIDAEIVPGILPVSNFRQLQRFAALTNVRVPQWMLAMFD
GLDADAETRKLVGANIAMDMVKLLSREGVKDFHFYTLNRAELSYAICHTLGVRPQGSVA
>E4N9T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)|TrEMBL
MALGIPSTRSDRAQTVRDLLAAGDRSFSFEFMPPRGEVGERKLWDAIRRVESLEPNFVCM
TYGAGGSSRGRTVDLVGRIATETTLTPVAHLTAVDHSTAELRNIIGQYADQNVRNVLAVR
GDPPGDPMGEWVRHPEGVTYAAELVELIKGIGDFCVGVAAFPQMHPRSVSWDEDIRHFVA
KCRAGADYAITQMFFEVEDYLRLRDRVAAAGCETPIIPEIMPVTNIRQLVRFPQLSGSDF
PPEFRRRLEAAADDPAAVRAVGLEHATTMAERLLAEGAPGLHFITLNHSTSTLEIYQNLG
LHTR
>A0A2N1QSK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistetes bacterium HGW-Synergistetes-1|TrEMBL
MRDYFEQMRPTMTFEIFPPKGSGDLASIFATVDALASLAPDLISVTYGAGGTSRENTVEI
ASQIQNSYAIPALAHLTCAGNSKDEVDPVLRTLSENGVKNILALRGDIAEGEQLKDFRYA
SDLISYIKSKYDFRIFAACYPEKHIEAYSVEDDLHCLKEKADCGVDVLISQLFFDNELFY
RFRDQARSIGIDTPIVAGIMPITSSSQISRMVSMCGATVPEKVQKIIRAFGHNSMAMKEA
GIAYATAQIVDLLSTGVDGIHLYTMNQPDIAKRISENIRGILYSLRVKRG
>A0A1G5EA55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 136MFCol5.1|TrEMBL
MRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVGPNFVSVTYGAGGSTRAGTVRA
TQQIAADSTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVRGDPPGDPMGEWVEHP
EGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDKCRAGADYAITQMFF
NPDDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFPQLSNATLPSSLKDRILAVKDDA
AAVRSIGIEFATEFCARLRSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A660Z657|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrothermae bacterium|TrEMBL
MSFRSNLERVLSEGGFAVTAEIGPPKGCDPDKIKQKASFLAGCAHAFNVTDNQTAVVRLS
SLGGSVILLNLGLEPIMQMSCRDRNRIALQSDVLGAVSIGVRNILFVTGDHQSLGNHPGA
MGVFDLDSIQLIQIVKNMRDDGVFQSGDKILAGNPDVFIGGAANPFADPVEFRVDRLEKK
IDAGVDFIQTQSVFNLERFNVWMDEVRSRGLDKKVHILAGVTPLKSLRMTERMKFHVPGV
DIPDEIYDKMKKTGDPKKTGYEIALDLVNEVKKIKGVHGVHITALFWEEVIPKLVEASGL
LPHP
>A0A1G3JDW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sideroxydans sp. RIFOXYB12_FULL_59_6|TrEMBL
MGNPTTPISFEFFPPQTPEGVTKLTAARQRLAAFKPEFFSVTFGAGGSTQDRTLDSIKQI
HAEGHGAAPHLSCVGSTRENIRLLLNTYKDMGIKRIVALRGDLPSGMGSIGEFQYANELV
SFIRAQTGEHFHIEVAAYPEFHPQAKSARDDMLNYKRKINAGANSAITQYFYNADAYFRF
VDETRKLGVEAPVVPGIMPVVRYSQLARFSEMCGAEIPRWMRKTMEGYGDDVESVQNFGL
DVVTKLCEKLIAGGAPALHFYTLNQAKASIDILQRLGFRA
>A0A1E7L059|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces nanshensis|TrEMBL
MAIGISATRTDNAATVRELLATGKPSYSFEFFAPKTEKGERSLWNALRRIEAVSPTFVSV
TYGAGGSSREGTVRNTERIANETTLTPVAHLTAVSHSRSELRNVIGQYADAGIRNVLAIR
GDPPGDPMGEWVKHPEGLTYAAELVELIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVD
KCRAGADYAITQMFFRTEDYLRLRDSSAAAGCETPIIPEIVPVTNVNQIETFARLSNATI
PDELADRLRAVEDDPAAVRSVGIEYATEMCATLMAEGVPGLHFITLNNSTATLEIHQNLG
LRNRS
>A0A2W6C2Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MVFGPCGGVRADGACEMAPRPCVFDDVVRWPGATTPGEPVDVPLVLTDFSAPPFDPDALS
DVTRILASSCDAVLVGEHQDRPDFPPPVLARLLLAAGITPWPTLACRDRNRIVLEQELHG
LRHVGVRTVLCVTGDGRAYDVRPEVTQVFDLDGTRLASLAASLRLIAAVVETPTAPPHAV
RPLRLVEKQRAGAGVAILNHVGAATELRRFMSAARAAGLAMPVIASVPVYTDPASAAALQ
GLPGLDLPASSVARVLAADDPVSAGVDAAVEEARAVLAVGGIAGVNISGSASSRGHIFAA
EVKAEIGRRIRLEAER
>B0XSG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)|TrEMBL
MHVKDMLTDNESAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEA
WEATEGGLRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
VITQMFYDVDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEAL
EPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQATQAVLEELKLIPSEETP
LQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSIRDITQIFVRYLEGKLDRLPWSDSPISGEANAIKDNLVQ
LNSRGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNP
DLTYHAVAKNRELRTNTRDSPNALTWGIFAGREIVQPTIVDTISFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQDIMDNWYLVNIVNNDFHNTYDLFDLFNGLEVKDLDLEVGPDTAETK
SQPNGAAPEEVAIKN
>A0A533ZSR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MGVRRLREVLESSEFVTTVEYNPPKGTDIAPIMDNAKALLGKVHGVNVTDNTAAILRAGS
LSVCRMLFEMGHDPVMQVTCRDRNRLAIQSDLLSAHILGIRNILCLTGDYPTVGDHKDAK
PVYDLDSVGVMQMIQVLNQGRDLAGHKLQGPTDLFIGAAITPEQDPPGPMLAKFEKKVNA
GTKFFQTQAFYDVEKFKAFMRAVRKFPVKVLA
>A0A417E9L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM34-9AC|TrEMBL
MNNTKHTKEQIRERIQQKKILFDGAFGTYYGGKHDTRQLPELANLEAPERVKEIHREYLE
AGAQILRTNTFAANSFCMDIPREQIGETLRSGLRLAREAVAEWRETTGETKEIYIAADIG
QIPGEAMAQKDALSREYEEICNIFLEEGADFFVFETFSEMEELLPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGEAKEIDAVGFNCGVGPSHMHRILQILEKPEGKLLTALP
NAGYPQMVTGRMLFTGDNKDYFVDRMQQMTALGVDMAGGCCGTTPEYIAELAGKLDLTQY
PQAKKDTEPEKQQAPKEDRSFYHTKEAEGRNRKLIAVELAPPMGIDDEKLMDAAHLLQKS
GVDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGI
HNFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFTQAPVSYGGAINQGRRNL
EVEIGRVKKKMAAGATFFLTQPISTKESADRVRRIKEETGARILCGIMPFVSLKNATFMK
NEMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVITMTEDFADGYYFSFPFNRVAMLE
KILN
>A0A8B5WV93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MHISDIFSAGRPTFSFEFFPPRKASAWDALFRTMSALDSLRPSFVSVTYGAGGLTRGRTH
DLVVRLKKDTRLDPIPHLTCVGHTENEISEILTTYAAEGVGNIMALGGDPPASAAGYDRS
GDRFRHAIDLVHFIREFNARGEHLDPRGFGIGVAGFPEGHPATPNRVLELEYLRQKVDAG
ADYVCTQLFFDNHDFYDFRERCAVAGITVPILAGLMPIQSAAGYARTPELALCSRYPGRL
QRKIHAAQSDEDISKIGMDWTLNQCYDLMANDVDGIHFYTLNRSPVTIDIFRRLGVSKTE
L
>A0A1E4AYQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. SCN 62-14|TrEMBL
MTPTLDQLHEYRTATDTPLFSGLPGDVAVSFEFFPPKSEKMEAQLWDAVTQLKPLDPSFV
SVTYGAGGSTRERTHATVARIVAEAGLPAAAHLTCVAASKAEIREVAEHYWEAGVRHIVA
LRGDAGEPGAPFTPHPEGYASAADLVSGLKEIADFEVSVAAYPETHPDAVSPEADIDNLK
RKLDAGATRAISQFFFSAETFFRFRDACAAQGITAPILPGILPVTNVAQARKFAAACGAE
IPAWMDGLFEGLDERPGARQLIAATIAAELCRRLYAGGVRDFHFYTLNRPELAYAICHLL
GKRPTGEAA
>A0A137NXB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Conidiobolus coronatus (strain ATCC 28846 / CBS 209.66 / NRRL 28638)|TrEMBL
MSIVEKLEKINLEVEGPKFSFEFFPPKTQQGIDNLYDRIERMNLLGPQFIDITWGGRCLE
MANNIQKQLGVDTCLHLTCTNMTINKLDETLEAAKAIGIKNILALRGDPPKNLENQPITP
QGSQLQFAIDLVKYIEKNYPGEFCIGVAAYPEGQPDSLEPQRELEFLKQKVDAGAKFIIS
QFFYNSELFINWYQRCREYGIKVPIIPGIMPIQNYQNFRRLTNLCKSNISVEILKKLNEI
QFDDEKVKEFGIQLVTQLITDISQKCPDIKCYHFFTLNLERSIKKILSNLNWGNNPTSGW
NPMTTQLEAWDDFPNGRFGDSRSPAFGEIDGYGTNLKLTPFEAIQHWGYPVDISDITRLF
VQFLEDKIPALPWTDRSDIRAESKLLINELIELNKFGLWTISSQPPLNGIPSDHSELGWG
PKGGFLYQKAFIEFFCTSEFLINLQSSILKTTNQDLTYLAVNNKKEFKTNLTQSKSGEYD
INTVTWGVFTSREIIQPTQIDKESFLAFSEEAFQLWNDWSLLYPPKSKTNQFLNNIGDEV
WLINIVQNDYFKTFSEFVQFLVNSGNQ
>A0A6C1QW73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MHIDDIFARGRPTFSFEFFPPRNADAWTGLFAEIRRFTDLSPDFVSVTYGAGGSTREKTH
ELVVRVREETPLDPIPHLTCVCHTRDEIHRILSAYARHNISNVMALGGDPPRGQECDPGD
FPHASDLVQAIVEFNRAGLHPDSRGFGIGVAGFPEGHPATPNRIAELDYLRRKVDAGAHY
ICTQLFFDNRDFFDFRERCAISGITVPIVAGLMPILSLQSFRRTPELALGARYPAELLRR
MQRCSNDQEIAATGMEWTLAQCRELIREGVDGIHFYTLNRSTATEEIFRSLSDVRRGAIS
>U7MVS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. KPL1989|TrEMBL
MAPRVSASAPLDESSDNPDNPDNAENTEPRTRSERTALSFEVIPPRHDADEKKISHLLET
LESYRPDYISVTSSCRSGWLDGTAKFISRIDRETNMRTLAHLACTAGTKQEMVAWINRLI
DSGVRGLLALRGDLPEGEVKLPEDHLQYADELVRLIREVEGQQAARFAAGRLAVAVASYP
NGHYQARTDDENFDVLLSKQRSGADLAISQLFFEAEDFLQFRRRAELAGIRIPQIPGIMP
ITSVRRLRRMAEFSSLPVPEHLVRRLENARDERAEGIAITAELVQAMVDNDVGSLHIYTH
NNAEVTQELLDAVGIRPPTAPG
>A0A3D5WYA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
RATSRVSTLVTAIMIEQQVGLETILHYTCRDRNLISMQADLLGAHAIGLRNILCITGDPP
KLGDYPDATGVFDIDSIGLTRMIYRLNGGFDISGKPIGKPTGLSHGVGVNPGRANFETEM
ERFRKKIDAGAEWAITQPVFDRAVMEEFLDYIERNGLHISIIMGIWPLSSLKNALFMKNE
VPGIEIPDEVIQRMEHCASAESAREEGVAIARELYESLKGSIQGVQLSAPFGRIDLALRV
IGK
>R4YJA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleispira antarctica RB-8|TrEMBL
MAKISFEFFPTQTDAGTEKLLKVRDRLAQENPEFISVTYGAGGSTRGRTRSIVKSVQESG
IAAAPHLSCVGDSKADLREILLDYKKMGIKRIVTLRGDLPSGAGMANSELRYANELVEFI
RQETGDHFTLEVAAYPEMHPQAPSFEADLKNFERKVKAGADSAITQYFFNADSYFHFVDR
VQAMGIEIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSESIVKFGEEVV
SNLSQNLLDQGVPGIHFYTMNQAEPSLAIWNNIR
>A0A1E4RHS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphopichia burtonii NRRL Y-1933|TrEMBL
MKISEKLEQAHSVALPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSTLTNDMVYTAQGALGLETCMHLTCTNMKVELIDEALEKAYKSGCQNILALRGDPPLD
GSESTGDFKYAKDLINYIRNKYGDHFNIGVAAYPEGHPEETDEQLILKYLKEKCDAGADF
IITQMFYDAENFIKWCSQVRKIGINIPIIPGIMPISTYSAFIRRAKWSQIVIPQHFLDAL
DPIKEDDYLVRERGTELVSDMCNQLIKSGYVNHLHFYTMNLERATIMILERLKLVEYIKD
HDVIGGDVLPWRKSLNPQRSKESIRPIFWQNRKHSYISRTSGWDEFPNGRWGDSRSPAFG
DIDLFATDLLRQSPKKAIELWGYPQSLKDFSELVISYINGDLKSLPWCDGAIGKDTEVIS
NSLVQINKKGFFTLNSQPSLNAIKSNDKIYGWGPKNGYVYQKQYLEFFVHRDTLKPLLTN
VDNYNKSAGSGSITYYSVDKEGNLFSNTKDGDINAVTWGVFPGEEILQPTIVERTSFLAW
KDEAFRLIDEWVKILQSQNVVKELDIPQEKINNFVQLMKSFADDFILCNFVNNNFFDDNQ
TVFNLINELNLPDLQ
>A0A194S432|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodotorula graminis (strain WP1)|TrEMBL
MRISDKIKKAEREGRPWWSFEFFPPKTSEGWVNLYDRIERMQQLGPIFVDITWGAGGSTS
DATTGFVKTAHSELGLETCMHLTCTNMPTEMVDQALKEAYDSGCRNILALRGDPPRGVEE
WKPVEGGFNHAIDLVRHIRKKYGDYFDIGVAGFPEGHPQSESPEAEIRHFKAKVDAGANV
VFTQMFYDADVFIDWGRRLRAAGITIPIVPGIMPIQTYAAFKRRTDFAGTIVPKELWDML
EPIKDDDAKVREFGTRYVADMCRKILNADLGIHGMHFYTMNLSRGTEMLLEELQFVAMAD
RVKPLPWRVSLTQKRRTETTRPIFWSNRQRSYLTRTREWDEFPNGRWGDASSPAFGDVDA
LQLALPHKPQDAVKIWGTPRSLGDISALFARFCRGDLKALPWSDQPAAKETSYIAEQLAK
INELGFLTINSQPRVDGVSSDDPALGWGPMNGYCYQKAYLEFFCPPQHVEALLAILDKAP
SITYHAVNKQGEFHSNTAPGPNAVTWGVFPGAEVIQPTVVDSTAFQAWKDEAYELGAQWA
LLYRESEPETHKLIQGIFDEFHLVNIVFNDYRNTDDDAVFKPFYELAQQNGVHLNGSSTA
ATTD
>A0A242N5H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia sordidicola|TrEMBL
MKPIELSFEFFPPKTLEGIEKLRATGAQLKTLNPKFVSVTFGAGGSTQQGTLDTVLEMMK
QGLEAAPHLSCIGSSKDSLRGILGGYREHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFNIEVAAYPEYHPQARSPKSDLDNFVRKVQAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPKWIARRLESFGDDKESIRAFGLDV
VTGLCERLVKEGAPGLHFYTLNGAAASKTICERLKLQGR
>A0A067MBT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryobasidium botryosum FD-172 SS1|TrEMBL
MKITQKIAQAEKEDRIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
ELSSELVKTCQGLIGIETCMHLTCTNMPAEKVDIALRDAKAAGCRNILALRGDPPAGQDT
WSAVEGGFVHGVDLVRHIRDNYDDYFDISVAGFPEHALLPKEEFDAELRWLKAKCDAGVN
FIFTQMFYDVDVFVRWVQAVRDAGITVPIVPGINPIQTWNGFQRATSLAKITIPKSYLDV
LEPIKNDDEKVRAVGIKLVAQLCRDILNAGLGIRGLHFYTMNLEKGTKMLLQELEFVPRL
EVIKPLPWRQSLTPTRRTENIRPIFWANRAKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGVSLKPTKEEGLALWGEPRTHADIFNLFSRFCLNTLKMLPWSDMPQLSETSVIALPLA
KMNELGYLTINSQPAVNGARSDHKIFGWGPANGYVYQKAYLEFFVSPELLTTLVSRISND
PNITYYAINKRGDLRTNSKYDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELGYQ
WSQIYDAGSPARALISDMMDTYFLVNVVHNDFHDADAIFRPFLGDNIPKPDPDAAKAKTN
GIKVNGKVPAVVVEEPEVAY
>A0A327LXZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium AsT-22|TrEMBL
MTGPYPDPPAFVSFELFPPKTDAGETTLARAVDQMASADPAYFSVTYGAGGSTRDRTARV
VDMVGSRTGRPVAHHLTCVGASRGEVDRLARGLHDKGITRIVALRGDLPEGQRLAPDGYG
DAAELVAGLRRVADFDISVAAYPEVHPEAASAMADLDHLKRKLDAGAARAITQFTFDTDV
ILRFVERARAAGITAPIVPGIMPVANFAGLKRFSAMCGATVPDWLARMFEGLDDAPETRA
MVATSVATEQCRLLMEAGLSEFHFYTLNRPEVSLAVCRALGITPAVPAESAA
>A0A2G7S214|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. LMG 10879|TrEMBL
MSGAVDRRAPILAGTPDRVQRAQAFIGAASLEVSAKALPALHAEAARIAPGTTISIPYLP
SEDDTARLAAVRAVRELGFEPMPHLSARRIVSRAALEHFIDRAVIDAGVERCLLIAGDLS
TPAGPFADSTSIIESGVLERAGIRVVAVGGHPQGHPVMTSADRWRVLERKCQRIEARSMK
PLIITQFAFDADSVLTWLNELRGRGITPPVLAGVPGPASIARLVRYAAMCGVSASTSMLS
RYGISIGRLLGTAGPDVFVDRLVDGLTEAHGQVSPHLFPFGGIAASMEWVEHYRMRAGEL
MAQDGHCPPHPPSPG
>A0A1J5DPU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium CG2_30_51_40|TrEMBL
MSDYKAGSNLEKVLKAGKFAFTGECGPPQGANITKLKEKAAHLKGCVDAVNITDNQTAVV
RMSSWAASLTVLQEGVEPNFQMVCRDRNRLAAQSDVLGVYSHGIRNMLCLSGDHQKFGNH
PEAKNVFDIDSIQLINVVKTMRDEGKFMNGQEIDVPPKLFIGAASNPFAEPYEFRVFRLA
KKIAAGADFIQTQCIYNMVRFRDFMKRVVDMGLHEKCYILAGVTPMKSVGMAQYMAKQVP
GMDVPDSLIKRLKGAPKGKAAAEGIKMAVEQIQEFKEMPGVAGVHLMAIEWEHRVREIAE
LAGMLPRPVV
>S2JUM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas plecoglossicida NB2011|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEAKVPAAPHLSCVGDTKDELRALLAQYKTAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQESADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQADASLAIWNNLKLPR
>A0A0Q9Y328|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. NAM3COL9|TrEMBL
MSQLIDKLKNNILVADGAIGTILYSEGLDTCPEAYNLTYPEKVAHIHRSYIEAGADIIQT
NTYGANFEKLKDFGLEHKVKEIHQSAVKIAKEAAKDDTFILGTVGGFRGVKQEDLGLSAI
QYHTELQVDTLVESGVDGLLFETYYDLEELTNIIKATKRKHDIPIIAQLTALNTNYLRDG
TEINTALQQVSASGADIVGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSQF
KYSDNAEYFGNVAQKLINEGVRLIGGCCGTTPEHIQFIKSSITDLKPVANKNVIPITKYT
STSSKSTQSQSLTSKVKQRPTIIVELDTPKHLDTDTFFRNIKKLDDANIDAVTLADNSLA
TVRISNVAAASIIKRQYDIEPLVHITCRDRNLIGLQSHLLGLSLLDINEILTITGDPSKI
GNLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKTKTNFNIAGAFDPNVRKLDGAVKR
LEKKLESGMHYFITQPVYSTEKIKEVYETTKHLDVPFFIGIMPVTSYNNAIFLHNEVPGI
KLSEEVLEQFEAVKDDKTKTKELSLKLSKELIDTVHEYFNGLYLITPFQKVDYTLELAAY
SKSITSTKQEAIL
>A0A5J6WND7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moritella marina ATCC 15381|TrEMBL
MKYSIELVPRSWETLNTEVEEVSQFGQINTLNIPDLLRFDVRSWDACDRLQDKFDEAIPH
LRAIDFDLRNGFPLTDFFRHSKINSVLVVEGDPPQDISHRTYRNTSCELIRIIKKELPYM
KVYAAIDQYRTSMRKELDYIHDKIDAGVDGFFTQPFFDLKFLDVYMDMLQGTEVFWGMSP
IHSETSKSYWENKNDVVFPSDFEATKEWNIEFGRAMIKKVQAQDDNVYFMPIRANASEYL
GKLLAED
>A0A0J5QGD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceibacterium sp. IMCC21224|TrEMBL
MTRPEVSFEFFPPKNIEATFRLWDTVNVLAPLAPRFVSVTYGAGGTTRDLTRDVVATLHK
HSGLRTAAHLTCVDATREETLQIARDFAAAGVTDIVALRGDPPKGANGFAPHPDGFNSSV
ELIEALNDAGDFTIRVGAYPDKHPEAPNATADVDYLKRKLDAGADEALTQFFFEADTFFR
FRDACAKAGIDKPIVPGIFPIENWKGARRFAESCGTHIPAWVIDAFETATRDGREDLLAT
AICTELCSDLLDGGVENLHFYTLNRPELTRDVCFALGITPAVKLENVA
>A0A1C6PQU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SceaMP-e96|TrEMBL
MRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALRGDPPGDPMGEWVRHP
DGVGYAADLVRLIKESGDFCVGVAAFPEMHPRSKDWDTDVAHFVAKCRAGADFAITQMFF
YPEDYFRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQQS
>F0R8M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola salanitronis (strain DSM 18170 / JCM 13657 / BL78)|TrEMBL
MKVIELIKASEKTAFSFEILPPLKGTGIEKVYETIDLLREFDPKYINITTHRSEYVYTEL
GNGLFERKRIRRRPGTVAVAAAIQNKYGIPVVPHVLCSGFTREDIEYMLLDLQFLGITDL
LVLRGDKAKHQSAFTPEEGGYSHAIELEAQINDFNQGIFVDGSPIKQPVHPFGYGVACYP
EKHEEAPNMEQDIYWLKKKIETGAQYAVTQLFYDNQKYFAFVDRLRAEGINVPIIPGIKP
FGKLSQLSVIPKTFKVDLPQELVSEAMKCKTDAEAAEVGVEWCISQCRELMAHGVPSIHF
YTVGAAQSVSRVAKAIY
>A0A0J0UXA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium IMCC26207|TrEMBL
MFLVDSRPIPSGLDLNQRAGPGAARSVCWSATRDEHCSSARPKYPKSMPRIADILTQASG
PTLSVEFFPPKTPVGDANLQQTIEDLRAVPLSFVSVTYGAGGSTRDRTRDLVVDINEHES
YPAMAHLTCIGHTKPELEALLDDYDRAGVHNILALAGDPPADGSPADGDFTYALELVELV
RARGDHFSVSVAAHPELHPRSQDTKGDRLHLAQKLSVADFGITQFFFSAPDYFRMVDELS
ALGCDTPILPGIMPLTNPEGVRRMAKMSGATVPEDLAVRVEGAGSADEAQAIAVEAALEL
SQELLNGGAPGLHLYGLNKSEIVLRLVDQLNLL
>A0A7Y8RVT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp|TrEMBL
MSFLEDIKRKTLIADGAMGTLLYSYGIDRCFEELNISKPDEVKRIHEAYVQAGADIIQTN
TYGANYIKLSRYGLEDETKQINEKAVRLARSAAGSAYVLGTLGGIRTFNKNAYSLDDIKR
SFREQLYLLLNEQPDGLLLETYYDLEEAREVLKIARKETELPIIVNVSMHEEGVLQDGTP
LSEGLKLLAGLGADVVGINCRLGPYHMITALEEVPLLEDAYLSVYPNSSLPSLVEGRLVY
ETDDEYFRNSAIEFRNQGARIIGGCCGTTPNHIRAMAEAVKDLPPVTEKQVKIRKKAAAA
VQNARTEPALNELAKEKRSIIVELDPPKQLNFEKFIRAAKELQSAGIDALTLADNSLATP
RISNVACGALLKQRLDMRSLIHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRIE
KKIACGADYFISQPVYSEEQLIKIREETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDAIREKMALAGDDKQKQAEEGLAIARSLLDAACDLFNGIYLITPFLRSDLTAELTAYIH
QKEKETTNVYHQ
>A0A1I4M5C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salibacterium qingdaonense|TrEMBL
MNIVSELNKRVLVGDGAMGTYLYDKGYSGSFESLNVTEPDVIQQVHQEYVDAGADVIQSN
TYAANDVKLKKYTLDEEVENINRQGMRLAKEAAGSRAFAAATVGGITGVQALDISRDTIG
ESYRRQIQTLVEESPDVFILETFYDWQELLETVRLLRSMTDVPVIAQAALGDVGVMHGGT
PVTEVFQELKRAGAEVAGLNCRMGPYHLVQSFEHVPLMEEMYFSAYPNASLPNLDDGRFV
YQSNPEYFYQRALDLKNEGVNIIGGCCGTTPDHIAWTAEAVKNTMPITEKETVPEPAREI
PAASRIHPPKQRLDVVNRDRPSVIVELDPPKKLATEKFIHGAKALHEAGADAVTMADNSL
ASPRIDNLAMAAAVQNRTKARPLLHLTCRDRNLIGLQSHLLGLHTMGIQDILAVTGDPSK
VGDFPGATSVYDMNSTRLITLIKEMNEGRSYSGNSLGEKTSFTVAAAFNPNVRNLHKAAQ
RLEKKIEAGADYFMTQPVYGKDQFENIYEEVKNLFVPIYIGIMPLVSSRNAEFLHNEVPG
IQLTDGIRSRMAACGEDREAAQAEGIAISKELIDESLRYFHGVYLITPFLRYDITAELTA
YVRENNNTN
>A0A503WRG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-2-2|TrEMBL
MIARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDTVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDDVTETQVDMVK
TAH
>A0A1L3I4U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter porticola|TrEMBL
MALLNFKKRDAGTTQPTSPEVEAFLENYSIEVMPRTASKVENFRDLLPAGTRVYIAHIEG
TPIEEMVETAKRLNAEGYPVMPHFPARIIQDEATLADWIARYQGEADVKQALLLAGGVAK
PHGAFDSSMQLLETGLFDKAGFTNLHVAGHPEGNKDIDPDGSMKNVADALLWKQKFSERT
DSEMALATQFAFEAKPIIEWADNIKAAGVDLPIHIGIAGPAKLQTLIKFAIACGVGPSLK
VLQKRAMDVSKLLLPYEPTDVIAELAAHKAANPDFNITNVHFFPLGGIKTNATWAINNGG
AAAQPVNSQG
>A0A1D2SGB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lautropia sp. SCN 69-89|TrEMBL
MQQAANMMPSPSRMPGVAAAVRELLAGASIEIAARELEDAAALAKGRRVFIPWTPNLDAT
AIIAATSRARELGLAPVPHVVARRLVSAAAARELLGELRRRGAESVLLVGGDLREPAGPF
RSSFEVLHSGLLQDCGFAQAGICGYPEGHPRIPDAVLRADLDLKLGHARSHGLRLYVVTQ
FCFDGATIARWAGELRARGVDVPLCIGVAGPTSVARLLKLGVQCGIGNSLRALRGRLGSL
TRLAATHDPAELIREIAAERLVQPALDPLSLHLFAFGGMAATAQWLSRSAEEPANMASG
>A0A3C1MZW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium|TrEMBL
VLAHLTCVSSTKEKVHNMLEIFKANGIENIMALRGDLPDGETPHHYEHASELIKEIKAFD
PNFCIGGACYPEGHPEAHNKNVDIENLKKKIDAGCDFLTSQMFFDNAIFYNFLFRAREAG
IQVPIVAGIMPITRKEQVKRAIQLSGSSVPGRFVSMVDAFGDNEPAMKQAGIIYATEQIT
DLIANGVKHIHVYTMNKPDVAKGIMDNLSEILK
>A0A1H7WXC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea lupini|TrEMBL
MNAFRPSRHGSRRPRVSFEFFPPKNEEMEVNLWDSVRRLEPLGPAFVSVTYGAGGSTRER
THNTVKRMIDETALKPAAHLTCVSASCAEVDDVIRSYWAAGVRHIVALRGDPAGGLGSTY
EPHPQGYHQTSDLVEGIRKIGEFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRASGIDIPILPGIVPVQNFKQTAGFARRTGASVPQWLADRFEGL
EDDAATRRLVAAAVCAEQVLDLIDRGVSDLHFYTMNKADLVYAICHLVGLKPEKAQAQQV
AAE
>A0A2E6W3R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetovibrio sp|TrEMBL
MTQSTDYNNNVFKSNIQKFLSDFTTEVTPLSAAKISNFNTILREETKVYVTFLPGSDYED
TLRTSKRLREEGFIPVPHIAARSLPSKFFLEESLKYLKNEVNVDELLLIGGAVEQPIGCF
ESSMQVMETGLLDKYDIRKIGVAGHPEGSPDIPDTEVTSALKWKNAFSERTEAELYIITQ
FCFDAKSIIEWDQSIQREGNKLPVRIGLPGIASIKTLLNYAIACGVGPSIKFLKRQSKNV
SKLMMTNAPDKQIVALAEYWTVNPTCGLTGVHMYPLGGIKKSSDWIYAAIDGNFSMDKNN
NGFLVNY
>A0A3D0J9L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium|TrEMBL
MKIIDILNQDKITLSFEVFPPKLTKNYDDVAFKAKEIAKLHPDFMSVTYGAGGGTSEYTL
NIAKEIKEKENVEVMAHLTCVSSSKEHVHNMIHRLKENHIENIMALRGDIPSGGSKFHDY
QHASELIKEIKASGDFCIGAACYPEGHP
>A0A2Z4IAW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacterium sp. KB-1|TrEMBL
MRITELFQRGEFVLTAEVGPPKGIELDHLIKDAHEFLKTRVHALNVTDNQSSVMRTGSLA
TCKVLKDEGLLPIFQITCRDRNRIALQSDVLSAALLGIENLLLLTGDYTTLGDHPQAKPV
FDLDSVSLTHAVKRIEEGFDIAGNAIDGAPPKFAKGAVVSPCSDSVDVQLAKMEAKVKAG
CEYFQTQGVYEPEKFIKFMEQAKQFGVPVQLGLIIPKNVGMCRYMNANVAGVHVPDDMIE
ELKADKEKTKAGDTGVEICARLIRECKEYAQGVHIMSLGWENRIPEILDMAGIAPITPQV
>A0A1S1CJ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC062F03|TrEMBL
MTTVHPALSFELFPPRSHASCESLIRTIAELEGTNPDYVSVTYSGDAKRRQKTLALLDYL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDVQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSARLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMSVPADLAYALETATSSAE
LHRIGVDYALNQCRTVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEF
A
>A0A161YXX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinomonas sp. TW1|TrEMBL
MKSELARKFQDASRGVYFIGTTPPKSSVQEEQLQEISAKLLNRLADIDVDGLIVYDIQDE
TSRIDKPRPFPFMETHDPRAWSKRLHLASDKPVVTYKSVSSRSAEAFSGWLTEAWEDYGI
RDLVLVGSPSSEGDIKLPLPEAYKTLAASEHDFNLGGVTIAERHAKKGDEHLRLSKKANA
GCDFFISQAVYNPQATADLISRYARTCREEGNTPKRIILTFTPCGSAKTLEFMEWLGISV
PEATKHRILDSETPLDESIKICRNALEQIIEVALPLGVPLGLNIESLTNRKEEIDASIQL
YRLLKATLDLKLAEQGLN
>A0A807LE00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kosakonia cowanii JCM 10956 = DSM 18146|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPEMYATDLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCASTGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPACNVAV
>A0A374B6N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. AF02-12|TrEMBL
MNIKEYIKEQRLITDGAMGTYYEEKYSEDTVIAEKENLKNPEQIKEIHLEYLRAGARLIR
TNTFAANTMFLADMQEVKETVRAGYEIAKEAVTAFQAENGKEIPVFIGADLGPIYDLDHQ
DYDNVLQEYKEICDTFLSCGADCFVFETQSDFTYIEPVTAYIKEKSDAFILVQFAFDKSG
YTRSGLSMQRVAVEASEMENVDAYGFNCELDSTHMYQFMKNLKFSSDKFVSALPNAGYPY
TLRGKTIYSNNASYYAEKMKDIAALGTDILGGCCGTTPEYIALLSGELQDVPKAVKKIEN
VVTQEVTRTPSIFEEKLSRGEKAYIVELDPPFSEDASKVMKGAEDLRKCNVDLITLSDSP
MARARMDAGQLAVKIQQKTGVAVMPHISCRDRNVIALRAGLLGMHMNDVRHFLIVTGDPV
SRADRERVTSVFDFNSIKLMQYVKEMNLEVFAQEPVYYGGALNYHGANPDAIIERMKRKA
EAGCGYFLTQPVYTEEDVERLTYIKEHIDTKIMCGIMPLVSYKNAMFVKNEMPGIHVSDE
IVNRYREDMTREEAEEVAIELSVEIAAKLYDIADGFYFMTPFNRTGLIARIIEAIRQEEE
RR
>A0A2G5RT83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus flavithermus|TrEMBL
MGLLDDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIEAGAEVIQTN
TYGANYVKLARYGLQDDVKEINEAAVELAKRAAKGRAYVLGTIGGLRSTNKSTISLEEVK
RTFREQLYVLLNEEVDGLLLETYYDFEELQTVLSIARKETTLPIIAHVTLHDIGVLQHGM
PLAEALRQLEQLGADVVGLNCHLGPYHMLRSLEEVPIPTHAFLSVYPNASLPQYRDGRFI
YETSEQYFEETARAFRDQGVRLIGGCCGTTPKHIAAIARALADRTPVCKKDVKQRHTIVV
QEAEQTKEPSLADIARTRRSIIVELDPPKKLGLTTFLEGAKALKEAHIDALTLADNSLAT
PRISNVAVGTIVKQQLNMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRI
EKKIECGAHYFLTQPLYSEKQIEDVYEATKHLPTPIYIGIMPLTSARNADFLHHEVPGIT
LSDDIRARMAACANDPVQSTKEGLAIAKALIDAAFDLFQGIYLITPFLRYDMTVELVRYI
HEKERLAKERTVYYG
>A0A6A3A217|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hibiscus syriacus|TrEMBL
MKVIEKIQSSQQDQGKVVFSFEFFPPKTEEGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDAIGDNGVATPEAYQNDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKT
KIPDEISAALEPIKDNDEAVKAYGIHLGTEMCRKILANGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRPLPWRRPANVFRIKEDVRPIFWANRPKSYISRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWVTPLKSIDDIQEKFQSYCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSPEKL
DALVKMSKSFPSLTYVAVNKNGNLVSNIGVKDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWCRSWSALYPDGDPSKKLLDQIQNSYYLVSLVDNDYMDGNIFGVFEDL
>A0A501PB99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emcibacter nanhaiensis|TrEMBL
MEETLWNSIRRLEPLQPEMVSVTYGAGGSTRERTHATVTRILRETSLTPAAHQTCVANSR
GEVDDILRQYWDEGVRHIVALRGDMPTVGQAYQPHPDGYSNAAELVAGAKKIGDFDISVA
AYPEHHPESGSAQADIDNLKRKIDAGANRAITQYFFDVDHYFRFMDKALAAGISVPIVPG
ILPVTNFATVKKFSQASGIDVPAWLENLFEGLEDRPECRQQVAATVAAEQCLRLYQSGVR
HFHIYTLNRAELTLALCHILGIRPHGETDEHSKLAS
>S0FRU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotignum phosphitoxidans DSM 13687|TrEMBL
MNLKESLEKKRFVVTSEVQAPLGDDEPEALVKSLSRVRGRVDGVSVSDVELEGVVGDSIQ
TCDLLLKNRFNAIYQTTTRDKNRYQLQKDLTSAHEVGVDNLLVFTEDYRISGDSLQESMF
FHVDSGKLASVLDHLRQGVTIEGNDLGKNFEFTLGSGVETPWGKQMPKRGMEELEDMLNV
GTGYFLTTPIFDVDQFEKFMKQVAPFRVPVIAEVMILRTAGMGKFLNRHFKSGLVPEWVI
QKLLNAPDRTKASIELFADTVKSLKDICQGVHIVTIGGEDKLARYLNAAKLR
>R7XUH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. CF8|TrEMBL
MPDHLAARLARRDSGYLLFGLTPPRRSVVPEEAQRIADVTLERLDALDLDGLLLYDIVDE
SDRTDQSRPFPYLPTIDPADYLANHLSAWERSVVVYRCVGKYTQPQLETWLRDQDPERVS
TVFVGAASRELAVQTTLADAQELRGRARPEILLGAVAIPERHAAGAGEDARLLAKAERGC
SFFITQVVYDAQAARNLVSDYYYACRDRGTEPAPMIFTLSVCGSLRTLEFLRWLGVQVPR
WMENSLRHSDDTLEASLAHCLATAHDLARFCRSLGMPFGFSVESVSIRKAEIDAAITLAH
RVRAEVL
>A0A3A9JV52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas wenyumeiae|TrEMBL
MRISVELIPRGEAELLTDAAMVRSVMPQVNAFNIPDLMRFPTRSWDACKLTSGILPASIP
HIRAIDIPPGEELPIADAIEAAGLREVLVVRGDPPHDMGHRTYPNSSEDIIRRFKRHSPN
LRVYAAFDPYRAGFRDEMTAVHRKLEAGADGFFTQPLFDLRLLEICAEMLHGQDVFWGVA
PVLGQKSQAYWETTNRVIFPAGFVPTLDWNRDFATKAVRAIQGFGGNVYFMPIRVNLAAY
LTDLLPS
>A0A1B8T629|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parainfluenzae|TrEMBL
MSYANEINTLNQHLADTNKKINVSFEFFPPKNEKMESMLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGIEAAPHLTGIDATPEELKEIAKDYWNSGIRRIVALRGDEP
KGYAKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIEAEIVPGILPVTNFKQLQKMASFTNVKIPAWLAKAYEGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHTLGIRPTTNP
>A0A1C4Q8R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SolWspMP-sol7th|TrEMBL
MASGTASTWTSEHPTVAEVLASGKRSYSFEFWAPKTPKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRTGTVRATQAIAENTTLVPVAHLTAVEHSVAELRHMIGQYADGGVRNILAVR
GDPPGDPLGDWVAREDGLTYAAELVRLIKESGNFCVGVAAFPDMHPRSENWDSDVRYFVD
KCRAGADYAITQMFFDPASYLRLRDRLSAAGCETPVIPEVMPVTSVRQLERLSRLSTAVF
PETVKERMLAAKDDPAAVRSLGIEFATEFCARLLAEDVPGLHFITLNNSTATLEIHENLG
LPHHRP
>A0A4Q1A3H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter trophiarum LMG 25534|TrEMBL
MFEILISKLQEDKYLTLETTPQHEPTMHNIIEKIKKFKIDTKVDGFTCTDNPLAKLKYSS
YFAALKLQMEFNKPVIATMTMRDRNKIALQSDLLGANDFDIRAILALTGDPANMSDQPNS
KGVYEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFAVVNSYAKNFGSLEKKMHQKI
QNGAVGVITQPVFDIDNVKKLLENFENAKENVEGEKRKSQLILGLFPITKLRTALFLSAQ
VPGIHVPQFWIDTLEKAHSISEEEEYKVGMQLSRNLYHEINKIHPKIHLMTANNRFDVAS
EIIG
>A0A525W9U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. CG24D|TrEMBL
MSKEPRRLSEVLSSGQFAVTIEYNPPKGTNISKVLESAKDLVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGRDMAGNKLDGSTAFTIGAAVTPEADPVGPMLAKFEVKV
KAGAQFFQTQAIYNPDLFASFMKVVRPYKVKVLAGILLLRNHKMAEFMNANIPGVSVPQE
MIDELKAAGDKAEDVGVEIAVRTINAVRAHCDGVHIMAIKGTHRLADIITKAHIG
>A0A7K0XGJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MREEGAGAGSDASRRSLGEVLSTGSRSFSFELFPPKTDDGERALWQTIRDLQGLSPSLIS
VTYGAGGSTRDRTVRIVGGIAAEPALTPLAHLTCVGASREEVRAVVDEFAAAGVRAILAL
RGDPPGGPGSAWVQHQDGFAHADELVEFIASMGNFSIGVAAFPEGHPESANLADDAVVLA
RKQDAGAEFAITQFFFDARDYERLVRDAAGHGCTMPILPGLLPVTNVAQIERFAALSGAA
FPADLAARFALVKDDPDAVHSLGVEVAAELGQKLLEMGAPGLHFYTLNRSASTLEVCEAL
GLGAR
>A0A845DQZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineaceae bacterium SB0670_bin_27|TrEMBL
MANPDQASSAGEWALHGGESHLRQVLEAGHFAVTAELNAPDSADAEDVYANVAELGDVCD
GINATDGAGANCHMSSVACCALMARAGYEPVLQMGCRDRNRIAIQGDLLGAAALGVRNVL
CLTGDDVSAGDQPEARRVFDFDALHLLRTAQIMRDQGVLLSGRKLTTPPEFFLGAAANPF
VPPQDLRHLRLAKKIEAGAQFIQTQYCYDVPIFEAFMRRARDMGLHEKVYLLVGVGPLRS
ERAAEFMRSRVPGVHIPDAVVDRLAKTPRKGKREEGIRICVEIIEEVKQIEGVHGVHIMA
YRQEETVPEIVERAGILREKQKE
>A0A538D081|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGVLVSSAVAGLRCPEEANIRAPESVVSLHTSFINAGAELIETNTFGANRHKLRSQFLEN
ELAAINETGVKLAREAREISGRDVFVAGSIGPLGELGGLAADERGPVFAEQAALLEGRGV
DLFMVETFFDLDELTTAIEAVQGVSSLPIVAMLTFDEDAETFGGVSAHDAVERLAAYELA
AVGANHGAGLHAALAALEAMGDGRPLAALPNVGLASLSGGRVIYPHATPEYFAEFAAQAR
ALGARVIGGCCGTTPTEIAAIARAVEEERQPTAPFAAAERELVVAAHERPEETELARKLR
AGEWITCVELDPPKGGTYESMLAVTKTLKDSGEVGFVDINDNPMARARANALMAAIAIER
TCAIETIPHVTPRDTSVMGLQSQLLAAHAEGVRNVLSVTGDPPHVGDYPGSRGVYEVDSI
GLAQVVTRLNAGED
>A0A7V8YPP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTKISDILSRGRSFSFEFFPPRTEKAEETLRQALIELEPLGPSYVSVTYGAGGSTRERTH
DLVVDILHNTSMTPMAHLTCCAHTRAELLEVVERYRDAGIENVLALGGDPPADLDLPPGE
LHYAVELAELVREVGDFSVGVAAHPEPHPKSPTRKSDRKWTAYKLSHADFAITQFFFEAR
HYFDLVESLRALGVDKPVLPGIMPATSIASIKRMSELQGSEFPAWLAEKLHAVEDDPGAV
WRVGVDEATRLCQELLDGGAPGLHFYTLNRSPATREIYTALGLRQGAA
>A0A268UAP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. 13S00482-2|TrEMBL
MIEECIHKLLNTKFLSYEINPPKAVSIGEELLEELKNWNGFDALICTDAPLAKFRPSPIL
TALKLQNFLKKPIIATLNMRDRNSIALQGEILGANELDIRMFLTLTGDPIKLGDQPDAKA
VFEGNSSLLIELINNFNQNKDLNHSLIKGHIRPIYPFGVINAHSNNLLSLKNKMRRKIKS
GALALFTQPIYDIENAKYLLDSCEEINQELQTNAKLVFGYFPILKYKSAQFLYSKLPGVF
VPKIWLEKLEKAHQRDEEEEHKVGFELSKNLFEKLCNIHHKIHFMNSNKIELAKKILC
>A0A7V9SUC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSRFVERLGEGPVIVADGGTGSLLSGRVPRLRVPEEANVVAPEAVIATHVAFIRAGAELI
ETNTFGANRHKLAAHLLDDRVAELVERGVKLAREAREVSGEDVFIAGSIGPYGDLDGGHS
TDEAYGAFREQARLLEGRGVDLFMVETFFDLAELEAAVAAVRDVSSLPIVAQLTFDEDAE
TLAGVPAREAVTRLEGGGIAAIGANCGLGPQAALAALSDMAEHSNGLALTAQPNVGLPSR
SGGRLIYPHATPDYFGEFAAQARNLGARVIGGCCGTTPGQIAAIRAAVEEGREPRPSLLT
VEREVAEVEAALAGPAGTTLLQRKLEAGEWIVSVELDPPKGTNMQAMLSVAARLKASGAV
DEVDINDNPMARARLSALVAAAAIERKVGLETIPHVTPRDASIMGLQSQLLGAHAEGVRN
VLAVTGDPPHVGDYPGSSGVYDFDSIGLTALLGRLNEGEDYSGKAIDAPTSFYVGVAVNP
SADDLKTELERFRQKLDAGARFAMTQALFDIEYLDRFLEVFGGESPIPILVGIWPVRSFQ
LAFRLHNEVPGITIPDPVLQRLEDAGSDAARVGLELGRDLLEASRSRAGGIYVIPPFKEP
AAALDLLL
>A0A1W4W7Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila ficusphila|TrEMBL
MAVSFRRSAIARVCLSMHTYSVTYEGSPNNTPGSSSYVPCLTFAPGQNESNQTVEQRIGP
LVAERTSRRRFFYGIEVTANEMGGGPPVCLNFNHFLPLLPTFVSVVWLNQRYWDVEPIGQ
VRSLQMAKHLATHIPVLPHLTAFRLSERRLNQFLDLNFSSILAVRGDQVHEDQRFRLALP
MIEHLRQQRENISICVGGYPEGYTNLGDFPPAFTKNIAFLKKKPEQIALLPRYVTIPRQL
CNS
>A0A7K0YEY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRPEKTMYSFEFFPPKDLAGEDRLWQALETLALHAPDFVAVTYGAGGGTRDRTIRITSEI
TARTKIPTVAHLTCVGSTRVELIEILDRYKDAGIKSILALRGDPVGGPRAPWTAVDGGLT
HADELITLAREHSDFTIGVAAFPDGHPNSGGDMNKDIDVLIRKQSLGASFATTQFFFDVD
KWKRLVDTLESRGCDLPIIAGVLPVTNVKLLTKMAELGGTPIPDSIASRFAAVEDNPDDV
RKLGVEIALDLCNELIDAGVPGIHFYTMNSSTATSEIFTSLQERR
>A0A7X8YWE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKITEVLASRMSFSFEVFPPKTDAGMDNLKEALPHYYKFAPDFISCTYGAGGGNAGRNVE
VCELIKADGATEVMTHFTCIGNTREKIDSELEHYQSFGIENILAMRGDLPAGWEGTHGDF
ANADGLIKYIKNRFPDFCISAACYPEKHILAPSFSSDIAHLRSKQDNGAEFLMSQLCHDV
EAFKVFVDRIRKAGITIPVILGVMPVLSKDAIIRMTLSNGCSIPADLAVIIGKYGEDPEA
FRQAGIEYTVNQIYKFIEANIDGLHIYALNKYEDVETVMELSGIRKAHHPEGGDA
>A0A7K0LR40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAFARRGGSLALRSKVSRLLGEGGHSISFEFFPPKDSDAEDALWGALIQLEDFDPSFVSV
TYGAGGSTRDRTIDITSSIGRRTSLTTIAHLTCVGSSRAELHEVIDGYSEAGIENVLALR
GDPEGGLGVPWVSHPDGLDHAIQLVEMLRERGDFCVGVAAFPEGHPESASLEQDARVLAD
KQRAGAEFAITQFFFRADDWFGLRDRAEAAGCTMPILPGIMPVTNLAQIKRFSALSGAEF
PAALAARFETVADDPAAVRALGVEVATQLCEALLDGGAPGLHFYTLNRSSATREVYRNLM
GRPDLERH
>G1N3J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meleagris gallopavo|TrEMBL
MVAMAAQNRWQTEGFQAAAIRRDQQGLQGSERNQKRSCTLGREGGVVSNGPCYRSHSPTC
APDADVRPRFALPQRAGRGAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRCAECDA
AGRALTMVNENQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRR
QDSGDRWFSLEFFPPRTANAAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMII
ANTAVNYCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVHGF
NHAVDLVKHIRSEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFR
PETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDA
AIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVS
AHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKS
PREELLKMWGEELTCEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETSLLKEQLE
KVNRRGILTINSQPNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKY
ELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWI
EQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPPQQ
>A0A7W1LHC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSSRLLERLDSGPPIVADGGTGTLLSGAVPRLRCPEEANLRAPESVVALHASFIRAGAEL
IETNTFGANRRKLAARFLEDELELINSTAVRLAREAREMCGGEVFIAGAIGPLGETERFD
VDETATLVAEQARILEGRGVDLLLLETFYDLDELIAAVEAVRGVSQLPLVALMTFDADGQ
TLGGVSAGDAAERLDGLELAAMGANHGAGPAAALNAIAQMQGSGRVLAALPNVGLASLAG
SRVIFPHATPEYFSEFAAQARQLGAGLIGGCCGTTPAQIAAIRSAIDQGRSPSSRLVVHE
RELHAASETIAEETTLARMLREQEFVISVQLDPPLGGSNEALLETARVLKESGKAHLVDV
NDNPRARARMSGMMASVAIERACRIETIPHLTPRDMTVAGLESLLLGTHAEGVRNILAVT
GDPPEEGDYPGARGVYEVEAIGLTKLIANLNRGEDNHGRTIDAPTSFFTGVAVNPSADDL
EVELDRFERKLEAGAQFAMTQVLFDLRYLDAFLAHFGGRSPIPL
>A0A7K1API8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTSLSTAQRYPEAVEIRSAKKAVTYSFEFFPPKDVEGEERLWAAISQLESIAPDFISVTY
GAGGSTRDRTIRITSEITAHTKIPTVAHLTCVGSTRDELLEILGKYRAAGINSILALRGD
PTGGPRAPWVTTEGGLNHADELVTLAAEFGGFSIGVAAFPDGHPASDGDIDKDVKVLIEK
EKRGATFATTQFFFEAKKWQHLVEKLDAQGSSMPIIPGILPVTNVKQLNRMAELSGVPIP
DHISDAFHSVESNPEDVRKLGVDIATQLCKDLLDAGAPGLHFYTMNTSTATREIYSQLKD
H
>A0A1Q7L0D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon 13_1_40CM_3_38_6|TrEMBL
MKITFELNPPKIVKDHHFNLVLLNQEIQKFTKRASELIDLVDGIHLTDSVLGIARISSVT
AASLIKKTGNHLNLSCSVRARDRNYTSICQFVSDAILIGVKGVLVLMGDDPVNGSRDLGL
KPSSVLKMLYYEKYNSVIDFYLTIPAKIKDPSCIQKKIDAKPSALVTQSIASLAELGEIV
DVVRSHKIPVVACIMVPSKNNQTSAEMIGLDWKEYQNNAVDFVRDAGDLASEVLLTSPNS
FQSGLELLERLRR
>A0A7W4WBS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbulbifer rhizosphaerae|TrEMBL
MTHSIRISFEFFPPKTPEGREKLYKTREALQEFQPEFFSVTYGAGGTTRETTADIVTGLR
RDGISIAPHLSFGGDNEETILGLLNQYKEAGVDRIVALRGDMPSGMGAVAQMVYANELVA
FIRRHTGDQFHLEVAAYPEIHPESESYDDDIRYLKAKFDAGANSALTQYFYNPDAYFYFI
DQCEKAGIDAPIYPGIMPITNFANLARFSRNCGAEIPRWLRLRMESYRDLEDVKKLGMEV
VTDLCETLLEGGAPGLHFYTMNQVEPNTTILRNLGFNQ
>A0A6I2ZXR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
AVRVEGAGSVDEAQAIAVEAALELSQELLNGGAPGLHLYGLNKSEIVLRLVDQLNLL
>A0A7K1EKZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTRIADLLATGRTFSFEFSPPKSADGSMSLGRTIAELEPLAPSFVSVTYGAGGSTREHTR
DTVLWVQRETSIPPMAHLTCVGHTHAEIADIIATYVDAGIVNVLALAGDPPKNPADARPS
DYTYATDLIEHLREISDLCIGVAAHPEGHPRSPDLATDRRLLAEKMKVSDFATTQFFFDI
EHYVSLVNDLADLGVDKPVIPGIMPVTNIGQVERMAQLSGAAFPDWLRARLEAGTSPEHV
RQIGVEAATQLCADLLDAGAPGLHFYTLNKSTATREIYAQLGLPVA
>A0A7K0L3Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTSLSTAQRYPDAVEMRSVKSGLTYSFEFFPPKDVEGEERLWAAMSALESIAPDFISVTY
GAGGSTRDRTIRITSEITARTHIPTVAHLTCVGSTRQELIEILGKYRSAGIKSILALRGD
PTGGPRSPWSATPGGLNHADELVTLAAEFGGFTIGVAAFPDGHPASDGDIDKDVQVLLEK
EKRGATFATTQFFFDAGKWKTLVDKLEAQGSTLPIIPGILPVTNVKQLNRMAELSGVPIP
SHISERFAKVEDNPEDVRKLGVEIATKLCEDLLEAGAPGLHFYTMNTSSATREIYSQIKD
ER
>A0A6L6EBA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGTKLRATSFSLEFFPPKDEAGEQRLWLALSELAPLAPDFVSVTYGAGGSTRDRTIRVTS
EITKRTQIPTVAHLTCVGSSKNELIQILNQFKYSGIESILALRGDPVGGPTAKWEPTADG
LNYAQELVEIAVEMGFKVGVGAYPDGHPASNHDLAKDITVLLAKERAGASFATTQFFFEI
DKWQGIVDKLAAAKSQLPVIAGILPITNVKQLNRMAQLSGMQIPADIAEKFTKLADDVEG
TRKLGVEIATNLGTELLRRGAPGIHFYTMNSAQSTIEIAQNLGLIQNA
>A0A2N0KVG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Casp-Chloro-G4|TrEMBL
MTIIDTLGFKRTISYEFYPPRGADGIPAVFRAINRLAPYNPDFISVTYGAGGTTRAFTEE
IAIRARRETDLTVMAHITCAGQSQQEIDGVLGRLQDAGIENLIALRGDPPAGEADFVPME
GGFAHATDLMKHIKANFNFCLAGACYPEGHVSSPDLQTDIEHTKWRVEAGAEFLITQLFY
DNDDFYAFVERARRAGIDVPIIAGVLPVLSASQIRRFTQLGGEVIPPKLDVILEQYAEDD
DGMREAGIDYATKQVQDLWEQGVQGIHFFALNRSYSISKILDNLNLPGHSAQ
>A0A4P5RXQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARISDLIAAGRTYSFEFFPPQSQAAQMSLGRAIAELSPLAPSFVSVTYGAGGSTRERTR
EVVTWVRKETDITPMAHLTCQGHRRSEIREILDNYADAGVENILALGGDVPLDGEVQPSD
YTFASDLLDDVLADGRFSVGVAAHPELHPRSPDRATDRRHLADKLGRSDFAITQFFFEVD
VYVRMVDELRSLGVDKPVLPGIMPVTNKSQILRMAAMSGAAFPEWLAQRLEAFEDPEDIR
RVGVQAATELGQALLDAGAPGLHFYTLNRSTATREIYANLGLPVEQ
>A0A5H2YEG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospira sp. I09|TrEMBL
MNDKTFSIEFFPPQTAEGVEKLRLVRDKLAALKPAFFSVTYGAGGSTRERTFSTVREIVA
AGLDAAPHLSCIGSSRESIRGILAEFQAEGIRRVVALRGDLPSGMADPGEFRYANELVEF
IRAETDDHFHIEVAAYPEWHPQARSADDDLQAFVRKVNAGANSAITQYFYNADAYFHFVD
AVRAAGVTIPIVPGIMPIASFAKLARFSDACGAEIPRWMRKKFEGFGDDADSIKAFGLDV
VTELCQKLLAGGAPGLHFYSMNQSGLTSEIWQRLGLGNR
>A0A538FIU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MIGGCCGTTPTEIAAIARAVEEERQPTVPFAAAERELVVAAHERPEETELARRLHAGEWV
TCVELDPPKGGSYESMLAVTRTLNGSGAVGFVDINDNPMARARANALMAAIAIERSCAIE
TIPHVTPRDTSVMGLQSQLLAAHAEGVRNVLAVTGDPPHVGDYPGSRGVYEVDSIGLSQV
VSRLNAGEDFNGKAIDAPTSFFLGVAVNPSADDLETELDRFHQKVEAGARFAMTQALFDL
AYLDRFEQLLGGWPIPILVGIFMVRTHQLAVRLHNEVPGIVVPEDVQNRLRDAGPRAAEV
GLELARELYAEAREKAGGVYVIPPFKQPEAALELLGS
>A0A2J6Q1F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyaloscypha hepaticicola|TrEMBL
MYIKDMLAEAERSGRPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGQLA
DLTCEMVSVAQSQCGLETCMHLTCTDMAKDAVDKALKNAYNSGCTNILALRGDPPRDKEK
WEATEGGFHYAKDLVTHIRQTYGNHFDIGVAGYPEGCDDQDDPELLLDHLKQKIDAGATF
IVTQMFYDVDNFINWVSKVRAKGITVPVVPGIMPVNTYASFLRRCNHMKCKIPPKWSAAL
EQVKNDDAAVRSIGTGLVAAMCRKILASGIHHLHFYTMNLAQATRMVLDELKLTPSDQRP
LKQALPWRQSLGLGRRDEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDT
YGIRLKGTNEQNRKLWGEPQSVKDIANVFVKYLENGVESLPWSEAPITSEADAIKSELIN
LNGRGFLTINSQPAVDGVKSSDPVYGWGPNNGYVYQKAYLELLVSPELIDELIARIERNP
DLTYYAVKKVGNLRTNAPSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCYSSLSPSRHLIENIMETWHLVNIVHNDFHQAHGLFPLFDDLEVEDLDKPVEVGKTNG
TVETNGVDAKPNAIENTPLTNGSVEH
>A0A538CB51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
FLPEGATVTVTSSPRRGLEPTLLLCERLAVGGFRAVPHLSARLVQGPGQLAEIVARLKGA
AVTEVFVVGGDSPTPAGPYGSAASLLEALREGGHRFERVGIAGYPERHPLVDDATLLQAL
REKEPFASYLVTQICFDAAAIFMWVRRVRGGGFRLPIFIGMPGVVNRVKLLEMSLRVGVG
DSLRYLRKHGGLIARLVRRGGYRPDSFLANLTPLLEEATSGVVGLHINTFNEVESTERWR
QGAIARHGYMELPAS
>A0A538MGQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MASRFEDRLAKGPVIVADGGMGALVTSAVPRLRCPEEANLRAPDAVVSLHVGFINAGADL
IEANSFGANRRKLAQHFLENDLEAINSAAVKLARQARETVGRDVFIAGSIGPLGEPASAR
VRHELFSEQAVILEGRGADLLMVETFYDLEELVDAIDGIREVSALPIVALLTFDEGAVTL
AGVTAQEAAQRLAGLDIAALGANHGAGLLAALTALEGMDGQKPLAALPNIGLASLAGGRV
IFPHASPDYFGEFAAHARELGAKIIGGCCGTTPVEIAAIRAAVEEERKPRTSLVLEEREL
AAALGEEQRETGLARALREGEWVVSVQLDPPLGGNVSGLVELAQGLKESGRVGFVDVNDN
AGARAGMNAVIVSSVLERAAGIETIPHLTTRDYTVMGLEAVLFGAHAEGVRNILAVTGDP
PEVGDYPGSRGVYEIDAIGLVELMARLNKGEDFNGRPIDAPTSFLIGVAVNPTADDLDVE
LDRYRRKIEAGAHFAMTQLVFDLEHLDRFFEQFGGPSPIPVLVGICPIWSYRFALRLNNE
LPGIAVPESLQEALRDAGPEAPEVGMAYAKELYEAAREKAAGVYLVAPYRRPLNVLELIS
>A0A4P5S5K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAKISDLLSQGTSVSFEFFPPQTDEAEEVLSRTIGELESLHPSFVSVTYGAGGATRERTH
DLVVEINQKTSMTAMAHLTCAAHSRAELVDIVSRYRDAGVENILALGGDLPDDPSLSAGE
LEHALDLVRLIRATGDFSVGVAAHPEPHPRSPSLAQDRDRGAEKLGEADFAITQFFFETR
HYFDLVEDFRARGVATPVIPGIMPVLSIAGTKRMTELQGSEFPQWFLDRLRLVEDDPAAV
RATGIEEATRLCQELLDGGAPGLHFFTLNRSTATREIAANLGLPN
>B5EAF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrifermentans bemidjiense (strain ATCC BAA-1014 / DSM 16622 / JCM 12645 / Bem)|TrEMBL
MRIVEKMNQAQQFVSLEFFPPKDRNEWPAFFNTVDRLSQINPLFASVTYGAGGSTKGDTL
EIVKRLQGGNGLDTMAHLTCVGAYRGDLQLFLDELALAGVKNVLALRGDLPKDTPPEFSA
CRTLLHASDLAAFIRESHPEMGVGVAGYPETHPEATDPESDLEYLKLKLDQGGDFVITQL
FFDNQLYFDFVAKARAAGVDKPIIPGIIPVVSLKVIQRIISMCGATLPPAYLAELEEADR
SGGAAAVQKAGIAYARRQAQELLDAGVPGVHIYTLNRDQAVLELVDGLLPS
>A0A537YQA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSSDREGEEVPATQTANRFLERLGQGPAIVADGGMGALLSAAVPRLRTPEEANLRAPDAV
VSLHVSFINAGAELIETNTFGANRRKLAHHFLEDRLEEINSTAVKLARDAREMTGRDVFI
AGSIGPLGEPVASRLRREIFAEQAAVLEGRGADLFMIETFYDLEEVVDAVEAVRGASSLP
IVALLTFDEGAETIAGITADEAAQRLAELDVAAIGANHGAGLLAALAALERMGKDGKPLA
ALPNVGLASLAGGRVVYPHATPEYFAEFAAHARDLGARVIGGCCGTTPAEIAAIRSAVEE
ERKPRALLQFDERELVVSLGEEQRETGLSRALRENEWVISVQLDPPLGGSSAGLVEVARA
LQESGRVGFVDINDNATARAGMSSLMVSATIERECGLETIPHLTTRDWSVMGLESMLLGA
HAESVRNILAITGDPPEVGDYPGASGVYEIDAVGLTRLITQLNRGEDFNGRPIDAPTSFF
HGVAVNPNADDLDLELERFQQKLEAGAKYAMTQIVFELECLDRFAERLGGSWPIPVLVGV
FPVTSHRLALRLHNEVPGIVVPETLQHALQDAGSNAADIGFTHARDLIAGSRRFAGVYVV
APFRKPLRVLELI
>A0A8J4PUK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polysphondylium violaceum|TrEMBL
MTSLKIIDKINEHKQKGQPFFSFEYFPPKTSEGVQNLFDRLGRMLLFDPLFIDITWGAGG
STSALTLEIAEQAQTVYGLETMMHLTCTNMPVEQIKFALDRAQQLGVRNILALRGDPPRG
EEWKKIEGGFSYAADLVKYIRENYGDYFGICVAGYPEGHSDCTSKEDDIKHLKTKVDNGA
DIIITQLFYDTDIFIDFVKKCREAGINVPIIPGIMPIQTYAGFKRMTTLSKTFVPQEIND
ALEPIKDNDEEVKKYGVQLCIEMSKKLLDFGVEGLHFYTLNLERSVRKVLKGLELISPDK
ISPYLPWAQSAAGNRLKEDVRPIFWNNRPRSYIARTGSWDEFPNGRWGDHRSPAFGDLSD
YHLGFQKEEVNAFGPAPQSEQDVYDSFADYCSGNGKVKKLPWNDQPLSAESDPIKDQLVF
LNKNGFLTINSQPAINGLPSTDKKHGWGGKNGFVYKKGYIEFFTSPENAQRLIDYIKKCP
MITYHAVNRKGESKTNTKGTNAVTWGIFPGKEVIQPTVVDNASFMVWKDEAFTLWENQWA
NSFAQDSTARDILNKMINEYYLINIVDNNFINGDIFQPFHDLVNNLTSPPLNVSQNGGSG
SSSPIVNSVNSN
>M8DJQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus borstelensis AK1|TrEMBL
MSANKKDLRAYLQDNLLIGDGAMATQLYRTGVPVGVSFEELCLSNPQFVHDVHKAYYDAG
ARLLETNTFGANRDALSRYGLEHKVTRINRAAVAIAREAAKADAFVVGSIGSILAGRVRQ
KAMDEFRDQFEEQAIALIHAGVDGLILETFLDVEELLLAIDVIRPLTDQPLICQLATLEV
GRTRDGYTLTEAFSLLQKAGADIVGLNCRLGPAEILRSYERVQVPEGALLSAFPNAGRLG
LTDGEYAYKSSPEYFAESAKRLREQGVRLLGGCCGTTPEHVKAMADALHGLAPQVRVNPS
ETENERPSLSSYNVRDRQKPSIVERVKTGTTIIVEFDPPKDLDTEGFLQGCCELHKAGAD
SITLADNSLANVRMSNMALGAIMKSQYGMDPLIHIACRDRNLIGQQSHLMGLHALGIDQV
LVVTGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGISFSGRPLKQKAQFIVGAAFNPN
VRQIDAAIKRLEKKVEAGADFIMTQPVYDAEAIRLVYESTKHINIPVFIGIMPLTSQRNA
EFLHNEVPGIKLSDEALARMRKVQGEEARQEGIKMAKELLDAAIPIFNGIYLITPFNYYA
MSVELIQYVRQKSSLLQASAQA
>A0A6S6SW84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Sulfurovum sp|TrEMBL
MLFLDRIITNYLLGLIKYMFEKFCKKLCSDETFISVEITPPHGASIKPTIEKIQALKLDE
KVAGFSVTDNPLAKLKMSGVLSAIQVQQAFNKPVIATMSMRDKNKLSLQSTLLGANDFDL
RCILALTGDPAKYSDQPEVKGVLERDSTLLLSIIYRLNNGLSYSNKELNPKPKPIYPFAV
SNAHAKDMRRIKKGMLKKLNYGARGIITQPVYNLENAKELLEIFEECKQESVRDTAKDAQ
LILGQFPVVRAKTANFISDKVPGITVPKGILEEMDLAAMDGLDKEQEVGFNISKEIFDDI
LKIHPKMHLMTHNRFDLCSKLIGEI
>A0A429H029|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSLFSQCLEQKQFCILVEYLCSNRDTPAVPPSLAGYPAMMTLADRVHSDEDPAPLELAQQ
YAPEIEKLLHFSGKGRDIQEFERFLDQAEQHGYHNLLLLSGDKLKNHNSGREIPAQRSRY
LESVSAVMAAKQRHLFNIGVAFNPFKYTEAERDAQYLKLHKKIKAGADFLITQLGFDLDC
LQHSQSFISQHYKQFPLIACVMPLTLKRAQFMLKHQVAGLVIPAHIVHVLKSEYETDPVQ
AEANVYARCALQILICKHLGFVGVHLSACHKLSEQQKLEQFLKQYENWSLAACEKAWKQL
WRMETGLELKPELATFSKPVPPAQILKYKQMHLMHQLFFASHAALGFGRFIFKANFWNKA
RPDQLLLKMEHWSKHPLVGCESCGHCRLDDTLYICPETCPKGLANGPCGGTSLDRCEFGD
RECIHSVKARLAKRLDQTEVLRSKLIPAISIETRYTSSWKNWFKHSESH
>A0A540PB20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces ipomoeae|TrEMBL
MGAAGLRALLHSVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLTARLAGH
GYRVVPHVPARLLRDDAHLKEVVVRLAESGVEDVFVPAGDADPPAGAYDGALPVLRRLTE
LGSPFTRVGVTGYPESHPLIHDDITVQAMWDKREHATYIVSNLCFDPRVLGEWIARVRHR
DITLPVHVGVAGPVQRAKLLSMATKIGVGESTRFLTRHASWFLRFAAPGGYSPHKLLTRA
ESALTAPSAGVAGLHLFTFNRIAETERWRRALLDRLEG
>A0A4Q7FY18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. Leo121|TrEMBL
MTEVAAPPFRTPAISFEFFPPKTEEMERNLWDTINRLAPLSPTFVSVTYGAGGSTRERTH
STIARILNETSLLPAAHLTCVSASRGEIDEIVDRYHEVGVRHIVALRGDPPGGIGTPYYT
HPDGYQSSPELVAGIKKRHPDIEVSVSAYPEKHPESANFDADIDTLKAKVDAGATRAITQ
VFFDNDLYFRYLDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTTVPDWFAAKFDGLD
DDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPNGAKKAA
>A0A3N5GDN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MTLESVTSAPAVARDTDFGRAIAQLARNASIETSTRNLADVAGYAPLLAPGTDVYVTFLP
GTPYHHILSVATRLRQAGLNPVPHLAARRFASAAAVADFAARLRDEAGVTRVLLIAGDSQ
TACGPFGSSLEVLETGVFQSCGIRSIGIAGYPEGHPGIPQQALDDALERKIRYAGTHGLE
LFIVSQFCFDGQRVLDWVTRLRERGVSLPVRVGVAGPATVRTLLSYSIRCGIGASMKALG
SRPVSLTRLLARHGPEQLASTVARPAAALGIAGLHLFPFGGFAESARWIADVAAGRFGLD
ERGKTIELPAVNRAAG
>A0A1I6N298|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yoonia litorea|TrEMBL
MPAPTVSFEFFPPKTLQASFRLWDCVNTLAPLDPSFVSVTYGAGGTTRKLTHEAVEAIQA
NTGLNVAAHLTCVDATKSETLGIADAYAKAGVKEIVALRGDAPKGASNFTAHPEGFASSI
DLIAALSERGGFNIRVGAYPEKHPEAVDQAADIAFLKRKFDAGATSAITQFFFEAESFFR
FRDDCVKAGIDAPIIPGILPIESWSGVQKFSKQCGAFIPQVLRDAFNNAEQTGTTELLAT
AVATELCDDLLQGGVDHLHFYTLNRPELTRDICHALGVTPKVQLQNVA
>A0A367W3Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira xiamenensis|TrEMBL
MTVKNDIAPQGTSRSDLRISFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGST
RDRTHSSVTRIQGETGIPAAAHLTCVGHTKEEIEGIARNYWDEGIRSIVALRGDLPDAGD
KYVPTPGGYPYAVDLVEGLKRIADFDISVSAYPETHPDAPSADFEIEYLKHKIDAGANRA
ITQFFFDNEVFLRFRDKCVAAGITAPIVPGILPVTNFGSLLKFADMCGASVPKRLHWRFE
DLDEDPDTRRMVAFHEAISQVEGLMAEGVTEFHFYTLNRAELTYAICHALGIRGVAQAAA
>A0A3N5GZE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MNTGSDTTLSFEFFPPNTPEGMVKLRDVRARLAAFAPEFFSVTYGAGGVTRDKTLATVLE
IAAEGRPVAPHLSCVGATRDSVRELLAQYRSHGIRRLVALRGDLPSGMRAAGDFRYASDL
VAFVRAESGDWFHIEVAAYPETHPQARSPGDDLEAFASKVRAGADSAITQYFFNADAYLR
FRDDVHRLGIDLPIVPGIMPIGNFAQLARFSDACGAEIPRWIRLKLAGFGDDVEAIRSFG
VEVVSSMCRRLLAEGAPGLHFYTLNQSAISGRILESIGFPHG
>A0A4R4VXZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea diastatica|TrEMBL
MPFRGTEDAVLAHVPRTIPLTVTTTEAKGLAATVDLAQRLAGHGYSVAPHLAARQVRDKR
QLADLVAQLREAGIDGIFVIGGDVTQPAGGFPDALSLLEVLDADGHHFRRIGIGGYPEGH
GSISQDLIDRAIELKARYATHVVTQLCFDAGTTAAWARRVKERGVDLPIHVGLPGAVSRQ
KLIRISAGLGLGQSARFLRKQQSMLWRFFLPGGYSPDRLVEWLAPRVSAPEGTLRGFHLF
TFNELEKTEAWRRRMLTRAGQQP
>A0A2T5C2J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mangrovibacterium marinum|TrEMBL
MKVIDIINQSDKTVFSFELLPPLKGNDASNIYRTIESLIDYNPSYINITTHRDEMIYKEM
PDGSIHKQVVRKRPGTVAIAAAIQHKYGIPVVPHILCGGFTKSETEHVLIDLNFMGIENV
LALRGDGVKGDTVFRPDPNGHANADELVKQIVDLRNGKYLDSDLKNTTPLDFCIGVAGYP
EKHFEAPNFDTDLGYLKQKVDAGAEYIVTQMFFDNQVYFDFVEKCRAEGITIPIIPGIKP
ISNLRHLTILPKIFSIDLPQDLVNELKKCKNNDDAKLVGTEWAIQQSKELVANKVPSLHL
YTMGMSDNARKIVEAVF
>A0A2N1A0D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychromonas sp. Urea-02u-13|TrEMBL
MTIETQQQKYFSAQYLAQLNQNIADINTEVGVSFEFFPPATPVMEETLWGSIARLKTLKP
KFVSVTYGANSGTRDRTHDIIKDIKAKTGMIAAPHLTCIDASKEELRQIARDYWDNDIRS
IVALRGDIPQGESKPHMYSTDLVKLLKEEGDFDISVAAYPEKHPEASNAQFDLDVLKAKF
DAGANRAISQFFFDAETFLRFRDKCVKQGIDGDIVPGILPVSNYKTLVKFAGLTNVHVPD
WMHKLYQGTDNDPMTRNLIGATAAMDMVKVLSQEGVKDFHFYTLNRSDLSYAICHSLGLR
PE
>A0A429M6E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
GAGGSTRERTLAAIEDFNGKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDL
PSGQVGLGELPYAQDLVRFIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGA
NAGITQFFFNPDSYFYFIERLEKAGINIPVAPGIMP
>A0A365Y524|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga flava|TrEMBL
MKVTEHIARAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPAYINVTYHRSEHMFKKK
ADGSFDKVEIRKRPGTVGICAAIMNHYNVDAVPHLICGGFSREETENALIDLNFLGIDNV
LVLRGDAPKNETFFEPDPHGHSYAIELLDQVAHMNNGMYLENDLQGGVKTNFCIGVAGYP
EKHFEAPNMQTDMGHLKRKVENGADYIVTQMFFDNQKFFDFVAKCREMGITVPIIPGLKP
LTSKKQMTILPRIFHVDLPTELSNEILRCKTDKEVEQVGTEWLITQSRELKQFGVPVLHY
YTLGKPNVVRKAVEAIM
>A0A2T4U9I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalicoccus saliphilus|TrEMBL
MSLKARLKEGIIVGDGAMGTLLYQEGIHGCFEELNITAPEKISRVHQAYIEAGAEIIQTN
TYAANRHKLARYQQENNVKELNEAAVAIAVKAAAGKAYTAATIGGVATMHQEKEPLEERV
ASLKEQADILLDTNVDGFLLETFYDFQELIELLKYLRPLTEKPIIAQATLGDIGVLHTGR
HLQEALEELEALGADVAGVNCRMGPYHMLQSLEEISLLKTAGISVYPNASLPNVRDGRFS
YQSNPTYFGDMTKALVEEGVVLLGGCCGTTPDHIRAIREAVERDNLVPVKSKQVKERTAQ
TFMDAEPQLPKLTDIPEGKTSVIVELDPPKALSGVPAFMDGAKALTNAGVDAVTLADNSL
ASSRIDNLALGTKIKSEGTRPLLHVACRDRNIIGLQSHLLGLHELGVRDILAITGDPAKV
GDFPGATSVYDMSSMDLIRLIKQLNEGTSFSGKDLGAKTSFTIGAAFNANARRLDREVQR
LEKKIEVGADYFMSQPVYSTERIKEIAEAVAHLPVPVYIGIMPLVSSRNAEFLHHEVPGI
KLTDEVREQMKALSGDREASEKEGIRLAKELVDEAMKHFSTLYLITPFLRYNITETLTQH
IREQERLTAGSR
>A0A831TSK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillaceae bacterium|TrEMBL
MKPDLREKLSSSILVGDGAMGTYLYQIGFPVGISYEELNLSQPEIIERVHREYYEAGARF
IETNTYSANRERLSKYGLEAEVEQINRAGVDIARRAVGDDAYVIGSVGSIRAGKRKNIRT
SQIEVDFAQQIEVLTGSSVDGILLETFYDLDEILIALKITRNYSDLPVICQLAMEDVGRT
SDGFQVSEAFEQLIAAGADIVGFNCRTGPNGIMRVLEKTNIPSHVPISVFPNAGIPDYID
GRYRYVSTPTYFAESAKRFADLGARVIGGCCGTTPAHIQAMAEALSNYVPNEPMDDLSTK
RQSASITVAEPINRPEIQFPVKEELSIIELVKKRHTVIVELDPPRDLDITKFMAGAAALK
IARADAITMADNSLAVTRMSNMALGSLIKDKVGIRPLIHIACRDRNLIGTQSHLMGLDAL
GIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGTAFSGKPLKQKAKFIVGA
AFNPNVKHLDKAVQRLERKIKAGADYIMTQPVYDPDIMERIHDMTRHLAIPIFIGIMPLA
TGRNAEYLHNEVPGIQLSDEVRRRMNGLEKEEGRQMGNQIAKELLDAAMPLFNGIYIITP
FLNYEMSVDLTNYVWKKSPFYS
>A0A830FN66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermogymnomonas acidicola|TrEMBL
MMLKSVEIVPRKSPGLEDLMEAGRVLDGVADMVTVPENPMGLPGIDPILSLYVATRGTSL
KPMPHITPRDKNGLQISAQVITGIKAGIDSFFVIGGDPISSQSESREVRELDVMGTIRRV
KRSTVYMKDYEGSVTVGSSLNPYRDVEEQVVRAKREAGADFFITQAVYEPELLQKEWIRN
RDFRLSLGFIPIRRESQLKSIEAMGVRLSEETKRKLSGSDPLAASRGILERLVEELRGYV
DGVHIMPLGRNDIAREFLEVV
>A0A1L5QVV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas vesicatoria|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTATKLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAVDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
ASLCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A0K1K0V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. NR 4-1|TrEMBL
MASHNFSIEFFPPKTAEGAEKLRATRAKLSALHPKYFSVTFGAGGSTQRGTLDTVLEIMA
AGEEAAPHLSCVGGTRESIRAILGEYKSHGIKRLVALRGDLPSGYGAAGEFRYANELVEF
VRQETGDWFHIEVAAYPEVHPQARSPQDDLQAFTRKVQAGANAAITQYFYNADAYFQFVE
QAQKAGVTVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTQLCERLLQGGAPGLHFYSMNQAAATTALWQRLVKD
>A0A2N3N982|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lomentospora prolificans|TrEMBL
MHIREMLEETERSGQPSFSFEYFPPKTAQGVQNLYDRMERMFMLGPKFVDITWGAGGHVA
ELTNEMVVQAQTLLGMESCMHLTCTDMGLDRVNDALRRAYKAGCTNILALRGDPPRDKEK
WEATDGGFKYAKDLVAHIRNTYGNHFDIGVAGYPEGCDDNKDEDLLLEHLKEKVDMGASF
IVTQMFYDADNFLRWVRRVRDKGITAPILPGIMPVATYASFLRRANHMGCKIPPEWMAVI
EPVKNDDLAVREIGKRLVADLCRKLLASGEIHHLHFYTMNLATATSMVLQDLDWLPSAER
PLKQALPWKQSLGLGRRQEDVRPIFWRNRNKSYVLRTQEWDEFPNGRWGDSRSPAFGELD
TYGIRLPGTSEQNRKKWGEPKSIRDVANLFVNYLENRLDSLPWSESPLTAEGEVIREDLV
ALNRRGLITINSQPAVNGVKSNHPIHGWGPSNGYVYQKSYLELLVCPTIYSDIIERIKRH
PDITYYAVTKDGTLESNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGID
WAHCFESSSPSRALIEGMMNNWYLLNIVNNDFQQPRTIFELLEGLEVEGVDTPTPAPVEE
PSAVALEPAPEPVVQANGPN
>A0A2N8LZW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp. MD8A|TrEMBL
MASTMKRISFEFFPPKTDAGKEKLLATQKKLLAKNPDFFSCTFGAGGSTRDNTRDMVNKL
RAQHGDTAPHLSCIGQSKDEILELVNGYKEAGVTRIVALRGDLPSGMGYAQSEIKYADEL
VALIRQETGDHFQLEVAAYPEMHPEARSFADDIDHFKRKIDAGANSGLTQYFYNADAYGY
YLDALQKIGCDAPVYPGIMPILNVANLLRFSANCGADVPRWLSCKLNDLKDDDAAVKAYG
EEVVTRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGL
>R5ZPK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus thermophilus CAG:236|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILLALDDMKGSAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVSDTLRELDAVGVNRILALRGDIIPGVEPLKDFRYATD
LIEFIKAEAPNFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIYAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETARHIYEATHSLFKHHSQVGAL
>A0A1G4Q522|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus tianmuensis|TrEMBL
MPLVKPDLREALRRQVLVGDGAIGTYLYQMGFPVGISYEELNLLKPDVIMDVHRRYYEAG
ARLIETNTFSANREKLSKYGLEQEMEAINRAGVELARKAVGDDAYIVGAIGSIRAGKRKN
VRTAKIKDDFCDQIEVLVDTPVDGLLLESFYDLEEMLIALKLIRKVSELPVICQFATEGT
GSTHDGILLTEALRMLTAAGADVVGFNCRSGPNGLMRSLQRVASMEGAPPISVFPNAGIA
DYVDGRYTYAATPQYFGQTARKFVDLGARIVGGCCGTTPEHIAAMAQSLQNYTPDPNALR
LLQEVGGRSETGRNVPLLQPVSSPPAPEPNLVKLAKERYTVIVELDPPRDLDIEKFMQGA
QALKNAGVDALTMADNSLAVTRMSNLALGSLVKERIGMKPLIHIACRDRNMIGTQSHMMG
LHALGIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKSLKKKANF
VVGAAFNPNVKHLDKAVQRLERKIESGADYIMTQPVYNAELIEKVYEATKHLDVPIFIGI
MPLASGGNAEYLHNEVPGIQLSDEVRQRMNGLKGEEGRAMGVQIAKELLDAAMCYFKGIY
LMTPFLAYEMTVQLTEYVWEKAQRLDSHLYPLSK
>A0A2I1E4L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus irregularis|TrEMBL
MKVINKIRKAHEEGRPSWSFEYFPPKTQQGVQNLYDRMERMYRLGPEFIDVTWNAGGTTS
QLTSEIVATAQSVYGLETIMHLTCTNMPKEKVDKALKDAKECGCQNILALRGDPPRGQEH
WEACENGFSHAIDLVRYIRQQYGDYFGIAVAGYCEGHVDNPDKDDDLYRLKEKVDAGADF
IITQVFYDVDIFLNWVKKCRAIGISCPIIPGILPIQNYSGFNRIITLSKTIVPQFVLEEL
EPIKDDDAAVKEYGIRLAVDMIRKMFADGIKCYHFYTMNLERSTRLILEALEFVPPIENV
KPLPWCPSLSAKRKKENVRPIFWRNRTKSYIARTEAWDEFPNGRWGDSRSPAFGELDGYG
VSLKHSKKGALELWGYPQKHSDIFDVFVQYCRGEVNSLPWSDQPLAEESNIIREQLAHIN
SLGYLTINSQPAVNGVRSDHKIFGWGPKNGYVYQKAYLEVFISPTQLDALIARIERDTNI
TYYAVNKQGDLKTNTQSDGPNAVTWGVFPGKEIIQPTIVEAVSFTAWKDEAFELWNEWTK
IYDTDSISAKLITDIADNWYLINIVHNDFHDSDGIFKIFEQISVTDYEADR
>A0A3N5LRK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium|TrEMBL
MKVVEHLAKATNPLISFEMIPPRRGGDINQLFNVVKDIMKYNPPFIDVTSHAAEVEYIET
PHGIKKRIKRKRPGTIGISVAIKNQFHIDTVPHILCHGFTREETEDALIELNYLGIENVL
AIRGDDLGYVKPLPDHKTQNIYAYELVNQISNMNKGIYLEDDLLDASPTDFCIGVGGYPE
KHFEAPNMSVEITRVKQKIDAGAHYVVTQLFYENRCYFDFVDKCRAAGITVPIIPGLKVL
TTKHHLANIPKNFYVNIPEELANEVLEAKQEHILEIGAKWAAKQAEELLNKGVPSIHFYI
MQSAKPIQKMFEFLKM
>A3D934|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella baltica (strain OS155 / ATCC BAA-1091)|TrEMBL
MAFHHAQHSQSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPGWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A3S2AK48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.06.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A139ML44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. DD04|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>M4F9A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica rapa subsp. pekinensis|TrEMBL
MKVIDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGSTA
DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK
FVQVEGGFGCALDLVNHIRSKYGDYFGIAVSGYPEAHPDVIGENGLASKEAYQSDLEYLK
KKVDAGADLIVTQLFFDTDMLLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCKTK
IPAEVMAALEPIQDNEEAVKAYGIHLGTEMCKKILAHGIKSLHLYTLNMEKSALSILMNL
GMIEESKISRSLPWRRPANVFRIKEDVRPIFWANRPKSYISRTKAWENFPQGRWGDSRSA
SYGALTDHQFSRPRARDKKLQQEWVVPLKSVEDIHEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLVKVNSKGFLTINSQPSVNAERSDSSTVGWGGPGGYVYQKAYLEFFCSKDKLD
ALVEICKALPSITYIAMNKGETWVSNTSQSDVNAVTWGVFPAKEIIQPTIVDPSSFNVWK
DEAFETWSRNWANLYPEEADPSRNLLEDVKNSYYLVSLVENDYINGNIFKVFSDL
>A0A246BDX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium haifense DSM 19056|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHVLCGGFSQEETEYLLVDCMYLGIDN
VMALRGDAMKGEQHFVPTVGGHRNAMDLVHQMNDLGRGKYLHDEKISAEENKFCIGVAGY
PEKHIEAPSINYDLKWLKQKVDAGADYIVTQMFFDNKKFIDFVKQAREIEINVPIIPGIK
PIATKGHLQMLPKVFKIDLPEDLISEVEKAKDNTAVKQIGIEWAIAQCRELMDFGAPVLH
FYSMGKSDNIKKIAKEIF
>A0A1V2KX35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. CcI49|TrEMBL
MTAVGNAARTTARTVAECLASGRTSFSFEFFPPKTAEGERQLWTALREVEALQPSFVSVT
YGAGGSTRDGTIRVTERIATETNLTPIGHLTAVNHSVAELRQVIGGYAGAGVRNVLALRG
DPPGDPQAEWVRHPDGVAYAEDLVRLVRSLGDFCVGVAAFPDKHPRSPDLETDARFLVQK
LDAGADFAITQFFFGADDYFRLVERVRRLGCDAPIIPGVMPVTNVAQIVRMAQLSGAEFP
ADLAARLQAVADDPAAVRAIGIEVATELSERLLAGGAPGIHFITLNRSGATREIYQALNG
>A0A2U2BDP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinilabilia rubra|TrEMBL
MSTVAELIRNTDKPSFSFELLPPLKGNSIQKVFNTIDKLKEFNPLYINITSHRDEVVYKQ
NAQGITEPQVFRKRPGTVAVAASIQHRYHIPVVPHMICSGFTRSETEYALIDLNFLGIHD
LLLLRGDCSDRHQFFKPEEGGNAYAIDLIHQVNNLNKGQFLDGTLMEPFETPFSYGVAGY
PEKHEEAPNLDSDIYWLKQKVDAGAEYIITQMFFDNDKFVEFVGKCRQSGINVPIIPGLK
PINSKNQLTVLPKIFHTDIPEALAKELRKCETKEQVSKVGTEWSIMQAKDLVSKGFNLLH
FYTMMASQCVYNIAKDVY
>A9G9E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum (strain So ce56)|TrEMBL
MVTKSKMERLLSERQFLVSAELTPPRHYDLEKLLKHARNMAGCVDVVQINDHLLSQARCA
NMAVGHFVKQEGLEPVLQFSLRHKNKIALQGDLLGMAALGLSNIIVLGGYPCAIGSDPDA
KEVSDVDSYAAIELTRRLTREGKLFNGDVVSPAPYFHVGTIDFPCAEQAIAGAMDRLAAK
IDAGASFIQVQAVFELASMRRWMAAVVERGLHERAHFIAAIFPFAGVDRLSFLQKVPGLV
VPDHLIERVRLSGDAEGESYRITLELIRGLRDIPGLSGIHMRSIGAEDWVPRLVDEAGLR
RSA
>A0A840D6M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides reticulotermitis|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLYQKNRLRRRPGTVAVAAAIQNKYNITIVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHETVFTPEGDGYHHAIELQEQINKFNKGVFVDGSEMKVTSTPFSCGVACYP
EKHEEAPNMDSDIYWLKKKVEAGAEYAVTQMFYDNKKYFEFVERAKAAGIQIPIIPGVKP
FKKLSQLSMIPKTFKVDLPEDLVQEALKCKNDEDAEQVGIEWCTNQCKELMAHGVPSIHF
YSIGAVDSIKEVAKVIY
>A0A1L7LK05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus troglodytae|TrEMBL
MSRLLEKLKTDILVADGAMGTLLYADGLESCHEYYNISHPERILAIHQAYIAAGADIIQT
NTYGGKRHRLKSFGHDKEVKTINQAAVHLARQAAGDNTFVLGTIGVSHGLKQCELSLEDI
ISQTVEQTRFLLETKQIDGLLLETYYDIEELEAALKALRPLTDLPIITNVALHEPGITEN
GRPLVEAFSHLVMLGADIVGLNCHLGPYHMIQSFKQVPLFAQSYLSAYPNASLLSFSSDD
NETPYHFSQNADYFEYCAKLFVEEGVRLIGGCCGTTPEHIKAIKRGIRGLKPIERKVTTP
LISQEDLIYEVEKKENLVDKVKKEITIIAEIDPPKTLAVDKFVDGVKALDEKGIAAITLA
DNSLARTRICNLSMASMLKDEIATPFLLHLSCRDHNMIGLQSRLLGMDLLGFDHILAITG
DPSKIGDFPGATSVYDATSFKLLSLIKQLNQGHGYSGASLKKATHFTVAAAFNPNVKNLS
RTGRLIEKKIAAGADYFITQPVFSEAVIQELSEVTKPYEQPFFVGIMPITSYNNAVFLHN
EVPGISLSESFLAKLEAVKDDKETCKKVALAESKKLIDAALAHFNGIYLITPFLRYDLTV
ELIDYIQARTATAAKKRA
>A0A7W0MMZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MATIADRVGALDCYSLEVTPRDTDAFAAVVRRLPPRTEVFIADLPNQDPELLIAAAVRYR
NAGFRPVPHLVARNFASAGQVRDLLEKLVDEAGVERVFVLGGDRESPAGPLADALDLIEG
ADLQARGIREVVLACFPEGHPRIAPDRLQQALEAKLAACARSGLDALLISQFGFDARPLL
EYARRLRARGIIAPLRAGVAGPADADTLLKFAAELGVGPSRQRLKERPAGRSLEQSPHEF
VEAIARAQAEEGSLRIEGVHFFSFGSTGRTIAWVERHRIGSGRA
>W4D4W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL R7-277|TrEMBL
MKPDLRSAWENNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYINAGAVL
LESNTYSANYDKLSKFGLEAKVADINRAGVRIARRAAGENGYVVGAIGSIRAGKRANLSS
SELKKFFSQQIAALLEEAPDGIMLETFYDVEELHLALKAVRKLSTLPVICQLAVDDSART
LDGLTLPEAFHILQQDGADVIGFNCNTGPNGIKRALGTLQGKLALPVSIYPNAGVADYVD
GQYRYGASPEYFGQMAPVFADMGSRIIGGCCGTTPKHIAEISAALKGYVVEPLPEPAAFS
APERIAVQEHLADDGGQGGGEPTLVDLVKERHTVIVELDPPRDLDIAKFMKGAEALRRAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIKQLNDGVAFSGKPLKQNAKFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIARIAKATEHLDIPIFIGIMPLASGR
NAEYLHNEVPGIQLSAEVRSRMAGLEGEAGRAEGVLIAKELLDAAIAHFNGIYLITPFMF
YDMSVQLLEYIWEKQGRKLSPLFR
>A0A7Y7A3S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MKRPEISFEFFPPRNIEATFRLWDTVQALAPLKPNFVSVTYGAGGTTRELTREVVATLHK
HSGLRVAAHLTCVDATRAETLAIAEQFRDAGVKDIVALRGDPPKGASGFTPHPEGFGSSV
ELIEALRKTGDFNIRVGAYPDVHPEAANAAADVEWLKRKLDAGASEALTQFFFEAETFFR
FRDACAKAGIEKQIVPGILPIENWKGARRFAEACGTKVPAWVIEAFEAAERDGRQDLLAT
AICTELCTELLENDVDKLHFYTLNRPELTRDVCLALGIAPETTLENVA
>K9W0Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crinalium epipsammum PCC 9333|TrEMBL
MNNFRAAVKAGEFLVTAEVAPPKGGDPALMVRMAQTLKGRVHAVNVTDGSRAVLRMSPVA
ASVILLQHGIEPICQLACRDRNRIGLQADLMGAHALGIRNILALTGDPVKAGDHPDAKSV
FDLESVRLLQLIRKLNHGLDCNDKPLTDGATDLFVGAAVDPESSSWSGLQRRFERKVEAG
AQFFQSQLISNFDKLEKFMDQIAAGTDKPILAGIFLLKSAKNAEFINRCVPGVHIPQHTI
DRLASASDPLQEGIKIAAEQVQVARQLCQGIHMMAVKREDLIPEILDLAGIPDQ
>A0A355RD46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MNTPEISFEFFPPASLNDSFRLWNTINALEGFQPKFISITHGTGNKPRALTQDLVETLLE
HKDLTVAAHLTCVDMSAESTLDLVKNLAAKGLKDIVALRGDPAPDHGGAFRPHPFGFQTS
CEMIAALKNLGGFKIRVAAYPQGHPESSSQAADLDWLKRKFEAGADEAITQFFFEADDFL
RFRDACVKSGIDAPIIPGILPIENWAKTCNFAKKCGVSVPLWLEEAFERATRDDRHDLLS
NAIGTELCDTLRSEGVDTLHFYTLNRPELTRDICLALGLTAKLSLKAVA
>A0A1F4C5C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_62_13b|TrEMBL
MSPAPLAVMPLRPENEGLLRESIMRLVGGASIEASVKNLAEVDTYPAFLPPASTVFLPWL
PGLPYTHLVSVAARLRQAGFEPVPHIAARRLPDRASADDLVSRLCGEAGVTQVLVIGGDV
DRPAGPFDSAAALLQAGLLQQRGMRRIGVAGYPEGHPRIPDDRLDGVLNQKMQWATQAGL
ELYVVSQFCFDGVAIERWLQRLHGAGVTLPVHVGLAGPASMRTLINYGMRCGIGASLRAL
RSHGVSLTRLAAQSGPESVVWHLAEAQERGALPLPLKLHFFSFGGVEKTARWMRAVSAGR
VRLSGRQFELTA
>A0A1M6YEH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chishuiella changwenlii|TrEMBL
MKVTEHIERANGKPLFSVEILPPLKGQDVNCTFKTLDPLVEMKPAFIDVTYHREEFVYKQ
KENGLLKRHQVRKRPGTVAICAAIQNHYKIDAIPHLICGGFTKEDTEDALIDLNFLDIDN
VLVLRGDPIKSEKTFVPEVDGNAYASELIEQVTALNKGVYLDDELQETNKTDFCIGIAGY
PEKHFESPNLAMDMFYLKKKVELGADYIVTQMFFDNQKYFDFVKKCREMDINIPIIPGIK
PLSTFNQLKTLPQNFYLDLPETLAMEVLKAKDKETVKQIGLEWCINQSKELLEFGVPGLH
FYTMSNSINTQKIANAIF
>A0A2E7VGZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutales bacterium|TrEMBL
ANKVSCGADFVTTQLFFDNAKYFSFVDSCRAGGIDVPVLPGLLPVGSLSQIKRFCAMCGA
TLPDELTRCLEAAGDDSSAVGQVGADWAYGQLAELLDDGAPGFHIYCLNKSKVVIEALER
LRADGRFRAG
>A0A367WA72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira profundimaris|TrEMBL
MMTVQEKQAARNDLRVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGTTRDR
THGSVTRIQGETGIPAAAHLTCVGHTKQEIEDIARKYWDEGIRSIVALRGDLPDAGDSYE
PTPGGYPYAVDLVAGLKEIADFDISVSAYPEMHPDAPSADFEIDYLKRKIDAGANRAITQ
FFFDNETYLRFRDKCNAAGISAPIVPGILPVTNFASLLKFADMCGASVPERLHWRFDGLD
EDPETRRMVAFHEAISQVEGLMKEGVSDFHFYTLNRAELTYAICHALGIRGTDKAAA
>A0A3D5PJJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MNAPQVSFEFFPPQSLEASFRLWDTVQVLSPLDPTFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNATREETLGIAKEFAKAGVREIVALRGDAPKGQDRFTPVEGGFANSV
ELIEALSATGDFKIRVGAYPDRHPEAESTQADIDWLKAKLDAGASEAITQFFFEADTFFR
FRDACVKAGITAPILPGILPIENWKGTRNFAKRCGTEIPQWLNDAFKTAERDGRSDLLAT
AICTELCSDLMGGGVDALHFYTLNRPELTRDVCHALGVTPKMDLQNVA
>A0A1M6VB92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWT2|TrEMBL
MKIVDILKQDKMSLSFEVFPPKKETSFESVKTATESIAALGPSFMSVTYGAGGGVSHFTL
DIAKNLKQKFGIPMLAHLTCVSSSKETVHQRIEDMKAAGIKNVMALRGDLTPELIEKGRD
NCDYHYAVELIRELKAADADFCIGAACYPEKHPESANQAEDIQHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGILKNVTAILGKNFK
>A0A512IEW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria turfanensis|TrEMBL
MEMLTDFSLEMTGRDVTALHEAAPGIPPGTRINVTFLGHEDPALRVAAARAVREHGFVPV
PHVSARRLRSPGELDAFLADLAEAGAAEQVLVVGGDPGTPQGPYEDALAVIRSGALQRHG
VRGVGIGGYPEGHPAVDDDVLWSALAAKTTALREQGLEATVITQFGFDTAPVLSWVAEAR
RRGIDAPVRIGVPGPAGVRRLLGHARRFGVATSAGIAQKYGFSLTHLLGTAGPDRFLQDL
AAGHDAGVHGPVRLHFYTFGGLGATAGWVRQFGGERVAS
>A0A2T7HBK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labrenzia sp. 011|TrEMBL
MSDTSSRRSHQAAPSPITASFEFFPPKSEKMADTLWQTVQRLAPLRPSFVSVTYGAGGST
RERTHKTVERILKETDLDPAAHLTCVGASRDEVDAIVRDYWELGVRHLVALRGDPLEGIG
TRYVPHEHGYAYASDLVAGIKKIANFDVSVSGYPEKHPESGSWQSEIDNLKRKVDAGADR
IITQYFFDNDMFDAYLDRIAAAGINIPVIPGIVPIHNFEQTMVFSAKCGTSIPQWLARRF
AGLANDPETRKLVGVAVACEQVMDLVDRGINDFHFYTMNRADLTYAICHMLGMGKPAQED
LAA
>A0A4U6S6W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium elkanii|TrEMBL
MTETISSVPNAPRAPKGPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTITRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAGIKRRHADIEISVSAYPEKHPEAKDFDADIDTLKAKVDAGA
ARAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A2D5BGY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MPQISFEFFSPKTISAAFSLSRAVESLAGFAPRFSSVTCSNDPAQTLDTLRALRRSGLGR
LQAHITCATQTPADLPAYLKAVQEAGAEGIVALRGDTAPKGLEVMDLIGCAKKNAMRDIF
VAAYPEVHPLAQSAQSDLDWLKHKQDAGATAAITQFFFHADFFLRFRDKAAAQGVTLPII
PGILPVQNWTSTQTIARSCGTAIAPDLAEGFARAEREGRAKMMAIAQATELCDNLIQNGV
EHLHFYTMNRAEVVCAICTALGKAPQQSLRSVA
>A0A558DXY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sedimenticola selenatireducens|TrEMBL
MTANQTDQKLFSFELFPPKTEEGMSKLQDNVRKLNRINPLYVSVTFGAGGSTQQRTFQSV
EWLVSEGIEAAPHISCISSSAEEIIQMLNQYKRQGIKRIVALRGDMPSGTGLAGRGELNY
ANELVSLVRREFGDHFHIEVAAYPEFHPQATNADADLKNFKRKVEAGANAAITQYFYNAD
AYFRFVESCEKLSITAPIVPGIMPITNYSSLSRFSDACGAEIPRWIRKRLEAYADDVVSI
RDFGLDVVSELCQRLLDNGAPGLHFYTMNQSGPTLKIWDSLTLRD
>A0A3D5L8D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp|TrEMBL
MELANAVQNVNGVTALAHLTCIASERPKIREVLTDLKEHGIENILALRGDLPQDSSLALS
TQFHHASDLMKEIRDFGGFCIGGACYPEGHPES
>A0A7W8BQL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albaduncus|TrEMBL
MLAAGKTTYSFEFWAPKTEKGERNLWDALRRVEAAAPSFVSVTYGAGGSTRAGTVKATER
IAADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWVPHPQGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVARFVDKCRAGADYAITQMFFQPE
SYLRLRDRVDAAGCDTPVIPEVMPVTSVKMLERLPKLSNASFPDTLKERILTAKDDPAAV
RSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPRA
>A0A6G1DEV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryza meyeriana var. granulata|TrEMBL
MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFDRMDRMVAHGPTFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQGVEGATPEAYSNDLAYLK
RKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTETCKKILASGIKTLHLYTLNMEKSALGILMNL
GLIEESKVSRPLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPLKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYVEFFCSKEKLD
QLIEKSKAFTSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWSRGWAFLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAFKEI
>A0A7T0R5K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. A30-3|TrEMBL
MREAQRALEAPLFSGLPGDIEVSFEFFPPKSDKMGETLWQSVETLAPLGPRFASVTYGAG
GSTRERTHQQVVRIQNEAGIPAAAHLTCVEATREQVDDVARHYWEEGIRHIVALRGDPPD
GQSRYSAHPGGYANAAELIAGLKKVADFEISVAAYPEVHPDSSDRKADLDNLKAKFDAGA
TRAITQFFFEPECFFDFRDQAAAAGIKGEIVPGIMPVMSFAAVQRMSGLCGTAIPHWMEG
LFEGLDERPEARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKA
>A0A1E8F8T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas lipolytica|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPGNENMEKTLWKSVERLAPLKPAYMSVTYGA
NSGERDRTHDVVKRIQQQTGVTAAPHLTCVDASADELKQIARDYWDSGIRRIVALRGDLP
KGVDKTDMYASDLVALLKDVHDFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTSVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKLYEGL
DEDDQTTRNLLGANIAMEQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVKPGNAV
>A0A356VWH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomicrospira sp|TrEMBL
MKSQSKHEQKISLEFFPPRTEKGMNKLKTVIQELSVLNPEYMSVTYGAGGTTQAKTLETV
KYIQQNTQFESAPHLTCIGATEESLTELLDTYEELGVKRIVALRGDLPSGMMNPGNFKYA
SDLVSYIKKTRGNTFKLEVAAYPETHPQARNCTVGMKWFKHKVDQGADAAITQYFYNVDS
YLYFIDNCEKNGIDLPIIPGIMPILNYDNLIRFSEACGAEVPRWLKCRLESFDDDQAGLL
AFGEDVVSNLAQKLLDAGAPGIHFYSMNQAEASLNIAKNLTFK
>A0A2U1LKR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Artemisia annua|TrEMBL
MKVIEKILESTSAGSSGKVVFSFEFFPPKSEEGVENLFERMERMVAHDPTFCDITWGAGG
STAELTLEIARRMQNMVCVETMMHLTCTNMPVEKIDHALESIKKDGIQNVLALRGDPPRG
QDKFVQIQGGFACALDLVEHIRKSYGDYFGIAVAGYPEAHPEVIESNGLATPEAYQKDLE
YLKRKVDAGAEVIVTQLFYDVDNFLKFVNDCRQIGITCPIVPGIMPINNYNGFIRMTGFC
KTRIPAEITAALESIKDNEEAVRAYGIHQGTEMCKKILASGIKTLHLYTLNNEKSALAIL
TSLGLISEAKVSRPLPWRRPTNLFRLKEDVRPIFWANRPKSYITRTIGWEQYPHGRWGDA
SNASYGALTDHQFMRPKARDKKTQEEWVVPLKKFDDISEKFMKYCLGQLKTSPWSDLDAL
QPETKIIDEQLGSINLKGFLTINSQPAVNGAKSDSPSIGWGPAGGYVYQKAYVEFFCSAE
KLNSLVEKIKAYPSLTYLAVNKEGNLLSNVGKSDVNAVTWGVFPAKEIIQPTVVDPASFL
IWKDEAFEIWSRGWAQLYPEDDSSRTLLQEVQNTYYLVSLVDNDYINGDLFTVFKGF
>A0A366KC71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium xylocopae|TrEMBL
MHRPIFSLEVFPPKRNAAVGTIYDTLDGMEGLKPDFISVTYGTGRQADRTATARICRTIL
QEYGIPAVAHLTAQYADRQVVDAALDMFERAGVTAVLPLRGDAIEGRRPAGVFKHASDLI
AYVHAAKPDMAIFAACYPETHPEAVSPESDVRYLKAKVDAGAGHLISQLFYDNAQFLTFL
DHARAAGINVPIEAGIMPITRVGQVRRMSDTCGSRIPPAVERILDKWGNDAEALREAGII
YASEQIAGLLAEGVDGIHLYSMNQPVVIRRIWRNIAPLFVGGAAA
>A0A5C8TEN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. WL103|TrEMBL
MPNAIRHRASRDGYHPIRVSIEFFPPKTEEMEKILWSSIERLAPLGPKFVSVTYGAGGST
RERTHNTVARMVTETGLKPAAHLTCVDATRDEIDAVVQSYWDAGVRHIVALRGDPAEGVG
HAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFENEVYLRYVDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLEGDVETRRLVAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKV
MAAKAA
>A0A2T7T7C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces scopuliridis RB72|TrEMBL
MRDLLATGKTSFSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSVTYGAGGSTRAGTVRA
TERIAADTTLTPVAHLTAVGQSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWIKHP
DGVRYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRYFVDKCRAGADYAITQMFF
DPEGYLRLRDHVVAAGCETPIIPEIMPVTSVKMLERLPQLSTAVFPPELKERILSVKEDP
AAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYENLGLHEQS
>A0A0D8CKU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira sp. HJ|TrEMBL
MKAVRKNLRVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGTTRGRTHGSVT
RIQKETGIPAAAHLTCVGHTKEEIDEIARSYWDEGIRSIVALRGDMPEATGKYEPTPGGY
AYAVDLVAGLKEIADFDISVSAYPETHPDAPSADFEIEYLKRKIDAGANRAITQFFFDNE
TYLRFRDKCVAAGIDAPIVPGILPVTNFASLLNFAGMCGASVPQRLHWRFEGLDEDPDTR
RMVAFHEAISQVEGLISEGVTDFHFYTLNRAELTYAICHALGIRGTEQAAA
>A0A0D9AAC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ES3-33|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLANFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTRSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A652Z058|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudanabaena sp. UWO311|TrEMBL
MIDSPQPIVEQPFHKFRTAIANKEFLITAEVSPPKGSDPTHMLEQTRSLKGRVHAVNITD
SSRAVMSMSPVAASVLIQQQIGIETVCQLACRDRNRIALQGDLFGAAALGITNILALTGD
PVKAGDSPDARSVFDYESVRLLQLIQKLNQGSDANGKALPHQGTNFVAGAAVDPQSPSWS
GLQKRFERKVNAGAQFFQSQLITDFDRLDKFVNQIANQSDKPILAGIFLIKSAKNALFLN
KFVPGVQIPDHIIDRLAKAKSPLQEGIAISAEQIQTARQICQGVHIMAIKAEHLIPEILD
LAGVSII
>A0A0M6XRG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jannaschia rubra|TrEMBL
MPSRKPTVSFEFFPPKSLEGSFRLWDCVSTLAPLGPEWVSVTYGAGGSTRELTREAVATL
GRQFDLRVAGHLTCVDASREETMEVARGFREAGVTDIVALRGDAPKGSEGFVAHPDGFAD
SVELITALAGNGFNVRVGCYPDVHPEAASAKADIDWLKRKIDAGASEAITQFFFDAETFL
RFRDRCVAAGIDAPIVPGILPIENWKNASRFAASCGAVIPDDLAAAFEVATRDDRADLLA
IAQAAELADTLIGEGCGHLHFYTLNRPELTRDVCVALGLAARPALSQVA
>A0A7W4XWE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineococcus radiotolerans|TrEMBL
MSDGLVADLRDAQRRFSVEFSPAHDEEGAQRQWRAVERLARLRPVFASVTYGAGGGTREG
TVELASRLAARTDLRPVAHLTAVGQSVPQLRGVVRDLLAGGVTDVLALRGDPDGDPRAPW
RAHPQGLQHADELVRLALAEGVRSAGVAAFPLGHPESRDLDEDLRHLLGKFAAGAGFAIA
QLTFDVEDFLRLRDRLAAAGCTAPLVPGLLPVTSPKVLEVTRRLTDGHEPSWLQRRLAPF
LDDRGAFREEGVRLALEDGRRLLAEGVPLLHLYSLNAAGNVETLVEELGLAGPR
>Q7VRL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blochmannia floridanus|TrEMBL
MSIFHATQQEILNQYLVELRGHVKVSFEFFPPKTDTMEGMLWNSINKLSRFNPDFVSVTY
GANSGKRDNTNRIIQDIKKRTSLIAAPHLTCIDFTPSMLRDIAQEYWNNGVRNIIALRGD
KSINKCSSLSSMYAVDLVSLLKKIGDFDITVAAYPEVHPEARTAQSDLINLKRKIDAGAN
RAITQFFFDVEQYLRFRDACVSIGIEIEIIPGILPIFDFYQLQRFVAFTKVRIPQWMYIL
FDGLEHDLDTQKLIGIAVAMDMVKILVKEGVRNFHFYTLNRSDLTYTICHALGVKASN
>A0A844WT57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella sp. Pas-s27|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSLKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVQPKDDF
RFASELVTFIKENGDFNVIGACYPEGHLEASTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYSFLDKAYDMGIKIPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMAKYEHHPEAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKSE
>R5FCT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium bolteae CAG:59|TrEMBL
MKIRDILAEGKPTLSFEVFPPKTEDAYDSVEKAAAEIAKLKPSFMSVTYGAGGGTSDYTV
GIASAIKEEYGVTPLAHLTCVSSTKEKVHHVLGELKERGIENVLALRGDIPQDGSTPREY
HYASELIWEIKKAGDFCIGAACYPEGHVESANKSVDIDYLKQKVEAGCDFVTTQMFFDNS
ILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTYLPSRFMSIVDRFGDNPAAM
KQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A7W8UUY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. HC6.4b|TrEMBL
MTFLTMNPIELSFEFFPPKTQEGIDKLRATRAELVSLKPKFVSVTFGAGGSTQQGTLDTV
VDMAKEGLEAAPHLSCIGSSKDSLRAILNEYRAYGIRHIVALRGDLPSGMGAVGELRYAS
ELVSFIRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAY
FRFVDDARQLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRA
FGLDVVTALCQRLVDAKVPGLHFYTLNAAASTKAICERLAV
>A0A6P8Y9N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila albomicans|TrEMBL
MEGYVESGITVGEVYKTENKTKFTCVNKLIYDQKEHCLNDPNIAEIVKEKSKRKEFFYGI
EIPLKMDLNTCLDFKMFLPQMPEFMSIVWTKQFSDAIRSASMAKLPNIQTVSHLTPFIPA
MAHISLHRLTQQHLNDFLDLNLNNVLVIRGDHVEEGQEYNYAYEAVKYLRAARGNRLAIA
VAGYPEGYTNLQVGPRNKALDIEYLKLKIDIGANLIITQLCYSAEKIIELIKDARIAGIT
VPILVGIIVPYSFSNYQIIERITGVRLSPEARIEVEQLSSDDTKVKDYFVQLMVRIIQQI
LEADLGIYGIQFFTLNHFEPVVEVLRELRSKGIPKNSKADC
>I3C5U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Joostella marina DSM 19592|TrEMBL
MKVTDHIKKANGKTMFSFEIIPPQKGKNIQELYNNIDPLMEFNPPFIDVTTSREEFVYIE
RDGLFDRKVTRMRPGTVGICAALKHKYNVDTIPHVLCGGFTKEETEYLLVDCQYLGIENV
MALRGDAMKHQRYFEPTDGGHTYATELVTQIRNMCEGKYLHETIEASNCSDFCIGVAGYP
EKHLEAPSLDFDLKKLKEKVDAGADYIVTQMFFDNSKFFEFLEKAKSAGINVPIIPGIKP
IAVKKHLQLLPQVFKIDLPEDLVNAVDSCKNNKEVRQVGIEWCIQQSKELKDAGVPLLHY
YSMGKSDNIKAIASALF
>A0A1V5GKK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.BinA205|TrEMBL
MSIKDLFQKKTVFSFEVFPPKKTSSIEVIYKTLDELHDLKPDFISVTFSAGGSSNNTYAL
DIASRIKENGVAPMIHLPCINYTKEEITETLDQIKARGIENILALRGDINPDIPPKKDFA
HASDLIEFIKEKGDFDIAGACYPEVHPDADSIVEDLRNLKKKVDAGASHLITQLFFDNEA
FYAFREKAELAGINVPIEAGIMPVVNKNQIERMVTTCGASLPNKFVRIMQKYEHNPEALR
DAGIAYAVNQIVDLAASGVDGIHLYTMNNAYVARKISEAISGIIGV
>V8I7B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis 21/39|TrEMBL
MTMSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLA
DFIQNDLAIPTIAHLPAIYLTKNKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYA
TDLIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERF
YDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLR
AAGLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKHIHQATHALFNHQSLG
>A0A2S6GG21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinokineospora auranticolor|TrEMBL
MTGLPLVFRSVSVVGCLRYAERMTSVVQRIRVGRPVFSVEFMPPRDHADEQRLWNAIREL
EGLDPAFVSVTYGAGGSSRDRTIRTTGRVARETTLVPMAHLTAVDHSVAELRNVIGWYAA
LGIRNILALRGDPPGDPNGEWVAHPDGLNYANELVRLVRDLGDFCVGVAAFPYGHSRSAD
MDSDTDNLIRKFDAGADFAIAQLFFEPEDFLRLRDRVAARGCEAPLLPGIMPITTRKTLA
KTIELSGAQAPSRIVDLLDPHTDPKGFRAAGIDLATEVSERLLAEGVQGLHFYTFNRSKA
TKEVVSRLNLVPART
>A0A0P9IHN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. apii|TrEMBL
MEVSSPMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLN
TVLQLENEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGEL
RHANDLVAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFN
ADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQ
SIQAFGEDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A426PZK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium bovis|TrEMBL
MCQESPGATTHRRSHQIAVSDTLTFTTPGRVPFSVEFMPPRDDAAETRLWNAAEAFHDLG
ASFVSVTYGAGGSSRRRTLRVARQLARKPLTTLVHLTLVDHTRDELRAILRDFADEGLTN
LLALRGDPPGDPLGDWVPTDGGLNYASELIDLVRSEPGCEDFDIGVASFPEGHHRARDLE
EDTRHTLAKLRAGARYSITQMFFDVDHYLRLRDRLAAADPEHGAKPVIPGLMPITSLRSV
RRQMELAGAALPAELERRLLRAAAGDEEANRPAVREVGIELTTTMAERLIAEGVPDLHFM
TMNHPRATQEVLHNLGMAPAWGPQWGQDAVR
>A0A1Z4GFQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabaenopsis circularis NIES-21|TrEMBL
MYHTHSPTVSLFQKAAQAGEFLVTAEVAPPKGGNPAHTIEMAATLKGRVHAVNITDGSRA
VLRMSSLVASAILLQNGIEPVCQMACRDRNRIALQADLMGAHALGIRNILALTGDPVKAG
DHPEAKSVFDLESVRLLQLIQKMNQGVDCNDKPLTDGATDLFVGAAVDPQCGSWSGLQSR
FERKVAAGAQFFQSQLITDFERLEKFMDKIASVHKKPILAGIFLLKSAKNAQFINRCVPG
VNIPEHIIDRLAKAKDPLEEGVKIAAEQVQTAQQLCHGVHIMAVKREDLIPKILDLAGVA
PVNQVLVK
>A0A1Q9TXD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis sp. CNR-923|TrEMBL
MFSFEFFPPRGPKSQARLWRAIREIEALGPSFVSVTYGAGGGTRDLTVETTERIATDTTL
LPVAHMTLVDHSVAELRHLIGRFSDAGVSNMLAVRGDPPGDPTGEWIRHPRGLTYAEELV
RLLKESGDFSVGVAAFPYKHPRSADVETDTDHFVRKCEAGADYAITQMFFDVDDYLRLRD
RVASRGCDVPIIPEVFPVVRLASIPHSEKLSGAPFPRWLAERYARLGEDADAVRSFGIEY
AQRMCERLLAEGAPGIHFITFNQSTATREIYREVAPGKRAGGAGRP
>A0A3S2UI53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Inhella crocodyli|TrEMBL
MTRVPVSVEFFPPNTPVGHDKLLNQVVPALQRLQPEYFSVTYGAGGATREKTLATVKAIA
ATGAQAAPHLSCVGATRETISEILAEYRAQGIRRVVALRGDLPSGTASLGEFRYADELVA
FIRETQGADWHIEVAAYPETHPQCRYAAKDLQHFAHKMKAGADGAITQFFFNPEAYFHFV
DEARKLGVTQPIVPGIMPFHNFHRIAQFAQRDGIDIPRWVALKMEGFLDDAASIRAFGLD
VITRLCERLVAGGAPGLHFYALNQSELVLEIGQRLGLTAPPAQA
>A0A1V2SN46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus azizii|TrEMBL
MAHTPSLSFEIFPPNPAAGNEKILSALRHMQDLAPHFISVTASNNKYNLEDTTVRLADYI
HNDLGIPSIAHLPAIYLTKEEVTNILVALDQIGVHNILALRGDRIPNITPREDFHYATDL
ISFIKDEAPHFDIIGACYPESHPDSPNQVSDIKHLKTKVDAGCSSLVTQLFFDNEVFYDF
QEKCLLAGIEVPILAGIMPIINRNQALRLLNTCENIRLPRKFRAILDKYEHDPESLRAAG
LAYAVDQIVDLVTQDVAGIHLYTMNNPQVANYIHHATYSLFKHSAV
>U3AAP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio azureus NBRC 104587|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKHLQPKFVSVTY
GANSGERDRTHSIIKDIKAATGLVAAPHLTCIDATREELNAIADDYWFNGIKNIVALRGD
IPPGGGTPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVEA
>A0A4Q1UNE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium betae|TrEMBL
MTDLTIPAHTDGQDAHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPAG
GIGTPYASHPDGYQTSDALVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARAFVTRAGTTVPDWF
AAKFEGLEDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A852VM98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janibacter cremeus|TrEMBL
MQDQPHALTSAAFPAPARNPREVLLFGLTPPRIETTPERVAEIAERTLARVETLPIDALV
IYDITDEADRNSQPRPFPFAEMLDPATYLSQGLTRWDKPAVVYRCVGKYDPEDLRSWLQS
APDNVMTVFVGSSSSDAEVRTSLPQAVEIHHQARPELPLGSVTIPERHIGRGDEHQRLLS
KQRSGSQFFISQIVYDIGAAKNLASDYRYAALESGVDVAPLVFTLSMCGSAKTLAFLQWL
GVEVPSWVRNEILHAQDPLDWSRQQAVGAARELADFCRYLGIPFGFNVESVSSRKVEIEA
AVALTHEIAELLERD
>A0A2N2L4I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-10|TrEMBL
MHENNFKEALLNSGVFCVTWELVPGRGAREAAQEKALAQARQAAEGAKIHALTVTDNPGG
TPAMSANFMGCDILQLGIEPLVHFTCKDKNRNSIESELYALDRAGVRNLLVMSGDYPVSG
FQGRPAPVFDLDPVHTLQLITEMNSGLTYPGIKGTVHHQPGSFFPGAVVSPFKATEAEQM
AQYYKLKKKIAAGAQFIVTQLGYDARKFHEVLLFMKQNDLNVPLVGNIYILPYGAAKMMN
RNDLPGSVVTDKLLEELDREKNDPDKGAGARILRAARMYAIMKGMGFDGVHIGGHNIKYE
QVEEIIRQGEQLTPQWADLVRHFDYPIPGGFYYYERDPETGLNGNKPTERQYRALDADVE
ASYGLSRLFHRLMFEPQKKRYGFMNSLCRRVEGTKMEGLFGKLEHITKIFLFDCRDCGDC
ALIDLAYICPMSQCPKNERNGACGGSFAGWCEVYPGKKKCAYVRAYARLKKHREEEQLEK
FYVPPCNWELHQTSSWINFYLGKDHTSKRQSKN
>A0A1F7LAS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium GWA2_70_23|TrEMBL
MAAPFVARLAERPLLGDGAMGTMLYSRGVPLDACFDVLDVNEPKLVQAIHAEYIAAGADW
IQTNTFGANRFKLGVHGLAGSVQEINLRGVKLARDVRESMGRDVFVLGSVGPLGKYLAPL
GAVEPDEARAAFREQAEGLLAGGVDGFVVETFSDLTEQRLAVEAIRSLCDLPIVATAAFT
DESVTFLGRSPLEVVRALRALPVQAVGANCSVGSSVLYDVLEQMLPEAGGLPVVIQPNAG
LPSRVGERLMYLSSPAYMADYAARMIAAGARMVGGCCGTTPQHIRAMREVVDRHVPGRAA
VQVTQPAARLEVGEAAALGPQAAPTRLARKLDAAEFVVTVELDPPRGHNIEKLVQGAKLL
KERGVEILDINDGSLGRVRMSVLPTAILVREATGLDINMHFTCRDRNLMGIQADLLGAHA
MDIRNILAMTGDPPRTGDYVNATAVFDVDAIGLIRVLAAMNQGLDATGNSVGEPTAFCVG
AALNPAAEEPAREMERFLRKVEAGARWVQTQPVYDLEVLDRFFAGTRPPVPVVVGVLPLH
SWRHAEFLHNEVPGITITDAARARMRSAGDRALRIGIEMAQELVAEVRRRYAGAYLMPSF
GRFEVVAEVLEALR
>R7FCF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:330|TrEMBL
MKIASLFAEKTVFSFEIFPPKKTSPIETVYDTLEALQDLHPDFISVTFGAGGSGNGENTL
AIARRLKERYGVLPMAHLPCIHYNKAQIDQILEQFQENGIENILALRGDRVEGLTPTTDF
NHAADLIRYIRSKTGSFDIAGACYPECHPEAPNMDTDIRHLKEKVDAGASHLITQLFFDN
DSFYDFRYRAARAGVNVPIEAGIMPVTNRKQIERMVTMCGASLPRKFTKMVQRFEDNPDA
LRDAGIAYAIDQIVDLVTDGVDGIHLYTMNNPYVARKISEAVGGIIKAATKC
>A0A3D9EFG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas oleovorans|TrEMBL
MASPARKGGAAHERDAVKPSLSFEFFPCKTEAGHEKLIATARQLASHGPEFFSCTYGAGG
STRDGTYRTVRQLNDEVGVPTAPHLSCVGDSKAKLRELLQQYREAGINRIVALRGDLPSG
MGLSGGGELRYASDLVAFIREETGDHFHIEVAAYPETHPQARSFTDDVRNFVYKMQAGAD
RAVTQYFFNADCYFHFVERVRKLGVEAPVIPGIMPITNYSKLARFSDACGAELPRWLRKQ
LEAYGDDTQSIQAFGEEVMTALCERLLEGGAPGVHFYTLNQAEPCIAIWRNLGF
>A0A2U0T8C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella langaaensis DSM 22999|TrEMBL
MSYAKEIDTLNQHIADLNGNINVSFEFFPPKTEKMEETLWASIHRLKVLKPKFVSVTYGA
NSGERDRTHNVVKSIKQETGLEAAPHLTGIDATPEQLRQIAQDYWDSGIRRIVALRGDVP
ANYQRELFYASDLIELLRDVAPFDISVAAYPEIHPEAKSAQADLINLKRKVDAGANHVIT
QFFFDVESYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMSAVTNVKIPSWMNKMYEGL
DNDPTTRNLVAASIATDMVRVLSREGVNDFHFYTLNRSELTYTICHILGARPA
>A0A5C5XAE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubinisphaera italica|TrEMBL
MNRLPDLLKSDSPLISIEIFPPKTEKGDELLYETLDTLSKFEPKFISCTYGAGGTTQTRT
LELCQHIQKTYEIPATAHFTCVGSSRDELIAWLDKAAAAGIQNIMALRGDAPKGETSFKA
VEGGLSYANELVSLIRERHPNMGIGVAAYPEKHAECLDADLDLANLKRKIDAGADAAFTQ
LFFDNDLFFAFRDRYEKAGCAIPLIPGIMPITEFSRIKRITEMCGTAFPAELSARLENVQ
DDSEAQLEIGIEFAIAQCQELLENNVPGVHFYALNKSQACQRILEALKTA
>A0A2D9W325|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MTNRNIPINFEFFPPKTEAGQAKLVAVANVLADEQPEFFSVTYGAGGSTRDGTRRTVLQL
NNEVGVPAAPHLSCVGDSREDLRTLLNDYRAQGIQRIVALRGDLPSGMGHASGELRYANE
LVEFIRAETGDHFKLEVAAYPESHPQAPNFETDLKNFIRKAQAGADSAITQYFFNADCYF
HFVDRVRQAGVDIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSDSIKAF
GTEVISQLCERLIEGGAPGLHFYTLNQAEPTVAVLRNLRG
>A0A1I8JJU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
DVPASPTSPSPAVAGVRRAVASAAQPASSTEASSDALTERDSGYQRGGNAWKASPATAGQ
QQRPSMNGTGGRAGRKASEGQTLRMESQQNGHAYESDAPKILCRVSSGDSSSSASNATEM
NDCHDSRPHSPVLPIAQYRPLISRINRRIEKGKRWFSCEFFPPRTASGAVNLLSKFDRFA
KGRPLFCDVTWHPAGNPMSDAPTSSIMVASAMLNYSGIDTMLHVTCVGLPEERMTAALER
AKGLGLKNILALRGDLPEAPEDGAGGSGDVNNGDLLGDFKYAVDLVRFIRKRYGSFFNIC
VAGYPTGHPEASSYADDLLRLKEKVDAGADFIITQLFFEADTFLKFQSDCRQLGIRCPII
PGVLPIQAYQSLRHIVKLSKLAVPDEIIRTIEPIKENDEAIRNYGIFQCTQLCRKLLESG
EVHGIHFYTLNREVATIEILRNIGLWHEDLPRPLPWKHSANHERCGELVRPVFWSNRPTS
YVHRTLHWEEFPNGRWGRPDAPAFGELKDYYLFYLTVRATKKDRLNMWGEQLASERDVWR
VFVNFVSGEPNANGFRVTRLPWSDEELQQESRAIRDQLVALNSRGVLTINSQPNVNGLPS
GDSTYGWGGPGGYVYQKAYLEFFLPGQFLAALEQVLDRFSPRVNYQIVNREGTVNRLNFS
QQEPIALTWGVFPASEIIQPTVCDNGAFMAWKDEAFGLWTQEWANLYPEGSDSRRIIQGI
AEDYLLVTLVDNEFPAENCLWSVVEQVLTTQSQQGALSGINSSSHLEVTVKAVALLLPRR
SGSFAGTLHLHRLAQLLASLFVVDSQPLVQQDAQQAHGVQLVPAGPAVGAVAFQTDFELL
KAPIATAETLYVAVHKWQAAKYGIPSGRAEPELGHYAERINVELLRQDSLQHLRGKEGGR
MQLGALYTVQTHLNTKLFLTFAPPTKQLVVQRHRAPPLLLRLHSGIDHSGVGEVSHQAKG
EPLSQIRVDALHRDVQLRGAFESEIGRQPGVHHVDGFAHQIVGQEDHPDDGQHAQVGHVL
PLDGADLASGQADLLRVGQQLLLVLVADPHRLPHLPAGERQQRVSGSLGDRVHYCLLATV
VNVDELLGHVVWLKMPMRDISMSRNAAAAIIFGTKRPTTVVNSKSTVTKWISFSISWNAV
MNSLSEPGSGDDSCGRGAFLSQASRTFEQSNMPNMRLVSFMYHGTSSLNLLHNWLPTLWH
LFTMSNRIVLHIFFIVFRNLAEAPFLALASATLDHGFAPVYPPVHVHDGLRLLLLFRLLR
FFQHSISLLGRLLQLRLHLVRVARLANFIVDVLFHLFLLNHEIVEHGLRTAGVLKVQRGG
AGVQPLEQEAQQQSGGHVLVRDVHERFQTELQAGLDQVAARQHEALHGQLSLVQIVHQRL
ERPAEHSLDNLAGHVAAAELEEQAGNEEEQYDDAPDDANAELQQADDGPSLRGEAQRKEL
RRAGHGCALLEAQRLVVAQPGVGHIRCALAHLGALLKYRADHPAKGVCTPQHSLQLQSGD
SGSWLSTANPPVGTETSGTVVSICRSVTAEPPVRPLAEATSPASRMALGSRPAKPS
>A0A850SG74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvularculaceae bacterium|TrEMBL
MTKLPFPERLKRGEPVLGDGAMGTMLHQQGTPINSCFDELNVSHPEQVARVHRAYLEAGA
DLIETNTFGANRYKLAKHGMESRVVEFNQAGVRLARKVIDASFREDVYLAGSVGPLGVRL
KPFGRIRLEEARAAFTEQIGALAGAGVDVILLETFSDRLELLEALAAAREAAPGLPVICH
MTFGQDDRTLLGDLPAQVARDLRRAGADVIGVNCGGGPEQLSRILQMMHQAVPDATLSAM
PNAGFPESVGERMMYPATEEYFADYALTFKAIGASIVGGCCGTTPEHIAAMRRALDRRDA
PLPAIQVLEARSEEDLFVPERPTELARKLAAGRFIVTVEMAPPRSFVPQKLLASAQLLQE
AGADMVDVADSPTARMRMSPWAVCHFLQSRLHLETVLHFPTRGRNLLRVQGDLLAAHSLG
LRNLFVVMGDPTKIGDYPEAMDNYDVAPSALIGVIKHKLNRGVDQAGNSIGQPTSFTVGC
ALNMFANDLDREIQTTVKKIENGADFALGQAVFEPGRIETFLHRYREITGTDFTLPVIMG
LIPLYSLKHAQFLHNEIPGISIPNSLMSRIEAAGDDAPIEGVQIAQELLRDIKGLVQGAY
IIPAFGRYELAAEVIDGMGVAG
>A0A443IWM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Siminovitchia fortis|TrEMBL
MSLLDSLKGRILIGDGATGTLLYSYGVDRCFEELNLTHPNEVIYTHKEYIKAGADLIQTN
TYGANYIKLSRYGLEERVKEINSAAVRIARKAAGKETYVVGSIGGIHGARFHNELEEEIK
RSFREQLYCLLLEGVDGLLLETYYDLDELTTVLKIAREVTDLPIITNVSMHEPGVLENGV
LLSEAFARLEDLGADVVGVNCRLGPYHVLKALETTPIPEKAFLSAYPNSSLPEYRDGRLL
YKSEPDYFKKFARFFRNEGVRLMGGCCGTTPEHIKALKEGIKGLEPITEKKVKSEPRIEL
SETKHDECTIFEKVKTKRSIIVELDTPKHLDTKIFFEGAKALKEAGVDALTVADNSLASP
RICNKTMASLVKRELGLPSLVHITCRDRNLIGLQSHLMGLHTLGIRDILAITGDPTKIGD
FPGATSVFDVTSFDLIKLIKQFNEGISFSGKSLKQKGNFRVAAAFNPNVHNIGKSTERLE
KKIQYGADYVLTQPVFSREKIIEVWEATKHLEVPIYIGIMPLVSSRNAEFLHNEVPGIKL
TEETRRRMNDAKSPEKEIQEGLSIARELIDTAIQYFNGIYLITPFFRYEITVELTKYIQQ
KTKELETAEGVSFALS
>A0A0E3LN73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina barkeri MS|TrEMBL
MLFNFREKLNSSKFLVTAEVSPPKGTKFSVSLEDARQLKGIADAINVTDNQCSIMHMSSL
AFSKLLLDDGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICVMTGDFPSCGDHPGSKP
VYDLDSVQLLQLIRKLDSGINFAGNQLNGGTSFCTGAVSGIDPEKPLQLIKLEKKVRCGA
DFIQTQAVYDVGMFEEFTEAIGHLEVPVIAGLIPLKSLGMAEFMNKNISGIHVPEEIMLR
IKDAPDPVEEGLSIASETIKELMKLSRGVHIMPIGSHKNTARLLSMAGISGK
>A0A8F9YI45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. DSM 110486|TrEMBL
MTIQQEVAGSGRRRPDLADLVRTMSYEVMPFRGTESAVLEHVPTAVPLTVTVTEAKGIDT
TLDLTERLLRHGYQVAPHLPARQFIDRAHVADVVTRLRETGGRSVFVIGGDAPKPAGEFA
DAYALLRAMEDLGHPFTDVGIGGYPEGHAKIPAPALERGLRQKAPLATRVITQICFDAAV
TGAWSAGLSASGIDLPVHIGLPGPVNRQKLVRISAGIGLGQSARFLRKQQNLMWRLLLPR
GYEPTKLARQLAAEAPRGGNVHGLHVFTFNELAKTEAWRQELLARVEGKDGRA
>A0A1Y3XG55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmiger sp. An50|TrEMBL
MRLSQVFRQKECVFSIEVFPPKKNGATPESLYPTLEKLAGLSPDYISVTYGAGGGKAGLS
TVQIAKHLKQELGVEPLAHLTGINSTREQVAETVQALQEAGIENVLTLRGDICPDAPRSK
DFFHASDLAAFVKSKGDFYLAGACYPEGHVESENLRQDVENLKYKLDAGVEHLVTQLFFD
NARYYRFMNLVRKAGIQAPVQAGVMPIVSARQVQRTVALSSASLPPRFTKMISRYDGDEA
ALFDAGIDYAIEQLRDLIEGGADGVHLYAMNNPEVARRVYEGIRDLLPEAKA
>A0A2N7UJU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas urumqiensis|TrEMBL
MSTQQHPLGISFEFFPPNTDVGRDKLVGVRDALAEREPRFFSVTYGAGGSTQDRTLNTVR
QVRESGFTTAPHLSCIGSEKGQLRELLARYRGEGIESLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPNLDKDVENFARKMQAGANIAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYAKLARFSDACGAEIPRWIRKQLEAYGDDSESIAAF
GDEVISRLCQRLLDGGAPGLHFYTLNQAAPTLRILDNITG
>A0A2I0M3B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Columba livia|TrEMBL
MCVLFVPTVLLLFPSSRELTMVNETQHTCSTSSSSKSDGGSSSGSESSKDSSRCSTPVLD
ADRHERLREKMRRRLDSGDRWFSLEFFPPRTANAAVNLISRFDRMAAGGPLFVDVTWHPA
GDPASDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDITANLQKAKRLGLKNIMALRG
DPVGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDVCVAGYPKGHPEAESYEADLRHLKEKV
LAGADFIITQLFFRSETFLKFMKDCQAIGITCPIIPGIFPIQLVKLSKLEVPQEIKDVIE
PIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWNEDPRR
PLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYL
FYLKSKSPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETN
LLKEQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTAL
LKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKD
EAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNS
PTQK
>A0A4V3GCX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 270|TrEMBL
MKVTEHIENAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
IMALRGDAMKDEQYFIPKAGGNDYAIDLVKQINLLNQGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVNKAREMGITVPIIPGIK
PIAVKKHLQVLPQIFRIDLPEDLIHAVDQCKDNAAIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASHIF
>A0A351ZH86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MSIKDLFSQKTVFSFEVFPPKKTSSIDVIYDTLDQLHDLKPDFISVTFSAGGSSNNALAC
DIASKIKESGVTPVMHLPCINYTKEEIRATVEELKRRGIENVLALRGDINPNIPPKSDFR
YASDLISYLKTLGQFDIAGACYPECHPDCDCIEQDIENLKKKVDAGAEHLITQLFFDNDS
FYSFQEKVAAAGINVPIEAGIMPVVNKNQIERMVTTCGASLPRKFVKIMQRYEHNPEALR
DAGIAYAINQIVDLAASGVDGIHLYTMNNAYVARKISEAVSGIIGA
>A0A5P1ZPC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces venezuelae|TrEMBL
MSPTFSFEFFPPKSPRGERTLWEAIRRVEALSPDFVSVTYGAGGSSRDRTIEVTKRIAAE
TTLRPVAHLTAVGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRGAWTPHPRGFTYAH
ELVELVRSLGEFRIGVAAFPEGHPRSADPAEDLAHFVAKCRAGADYAITQMFFDPEDYLR
LRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAKGDPAAAYRVG
VEHATGMGLRLLDEGAPGLHYITLNKSTAALEIHRTIMSARSVVHV
>A0A3D2N1S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKTCDIFKQKTTLSFEVFPPKSDTPIDSIYSTIDGLAPLKPDFISVTYGAGGSGSNATIG
ICEMIKEKYGIEPVAHLACINLTKEKVLFELAQMRAAGIENILALRGDINPNVPPHEDFR
YAAELIELIKESGDFNILGACYPEGHPEAPNMVEDIRHLKEKVDAGCSQLISQLFFDNED
FYAFREKAAIAGIDVPIEAGIMPVTNPKTIARMATLCHAKLPKKFLTIMSKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAAKICSAVQSLFK
>A0A1I8GXI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
MESQQNGHAYESDAPKILCRVSSGDSSSSASNATEMNDCHDSRPHSPVLPIAQYRPLISR
INRRIEKGKRWFSCEFFPPRTASGAVNLLSKFDRFAKGRPLFCDVTWHPAGNPMSDAPTS
SIMVASAMLNYSGIDTMLHVTCVGLPEERMTAALERAKGLGLKNILALRGDLPEAPEDGA
GGSGDVSNGDLLGDFKYAVDLVRFIRKRYGSFFNICVAGYPTGHPEASSYADDLLRLKEK
VDAGADFIITQLFFEADTFLKFQSDCRQLGIRCPIIPGVLPIQAYQSLRHIVKLSKLAVP
DEIIRTIEPIKENDEAIRNYGIFQCTQLCRKLLESGEVHGIHFYTLNREVATIEILRNIG
LWHEDLPRPLPWKHSANHERCGELVRPVFWSNRPTSYVHRTLHWEEFPNGRWGGQMRLLL
ASSRTITCSILPKDRLNMWGEQLASERDVWRVFVNFVSGEPNANGFRVTRLPWSDEELQQ
ESRAIRDQLVALNSRGVLTINSQPNVNGLPSGDSTYGWGGPGGYVYQKAYLEFFLPGQFL
AALEQVLDRFSPRVNYQIVNREGTVNRLNFSQQEPIALTWGVFPASEIIQPTVCDNGAFM
AWKDEAFGLWTQEWANLYPEGSDSRRIIQGIAEDYLLVTLVDNEFPAENCLWSVVEQVLT
TQSQQGALV
>A0A7D3VYY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura verrucosospora|TrEMBL
MTGEHFEVICEIEPPVRPELARVRHQIGVLSPVADSFLIPDNHIGRATVSSVAVAHEVQA
MGASGIACLNSRDRNLLGFRRDLLTAAAYGVDRFLFVYGDKPTAGGRTSELTVRAMIEEM
RGAAEDPVFAGCGPFRAGVATGLRAVPPWKAQADFVFVQVSYSLDALLRWRESVRLDVPV
YAGVMVLASAGMARDLAAKIPDIAIPDDLVAAVERDRDAGVDAACEHVLAIRDSGAFDGV
HLVPVSRYRQVAARLEQDL
>A0A8C5EAX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gouania willdenowi|TrEMBL
MGKQTPHGDGNWQSSKSDSSGASGGDSSKESSRCSTPVLDADRSDRLRDKMRKRIESGDH
WFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVN
YCGLESILHLTCCNQSKEKITAYLNKAKHLGLKNIMALRGDPVGSEWEDEEGGFNYAIDL
VKHIRSEFDDYFDICVAGYPTGHPEAETYEADILHLKEKVDAGADFVISQLFFRADTFLK
FVNDCRAIGIKCPIVPGVFPVQGYQSLRQLAKLSKLEVPEEITRVIEPIKDNDAAIRNFG
IHQAVEMCRLLLDSGIVPGLHFYTLNREVATMEVLRQLGLWNEDPRRPLPWAMSAHPKRK
VEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALL
QMWGEELMNEQSVYEIFTCYITAQSNPCGHKVLCLPWNDEPLAPETNLLKDELEKVNRRG
VLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKILKKYEPRVNY
HIVNVNGRNWTNANDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKL
YEDESPSRMIVKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLSQWGRENFKTNIQLF
NI
>A0A260QST4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 15-649-1-2|TrEMBL
MDRLRSDGAARIPFSVEFSPPRDEAGEARLWRAVREFEQLQPAFVSMTYGAGGSTRDRTV
RVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRGISNILVLRGDPPGDPLGDWEK
HPDGVEYADELVTLVRELGDFHVGVASFPEGHYRALNLEQDTQVLVNKLRAGAEYSITQM
FFDVDDYLRLRDRVAAFDPEQGAKPIVPEIMPITSLRTVRRALALSGSALPKALDDRFTA
AAGTGREEDRAAVREVGIELATQIGERLIAEGAPALHFITLNFAKATREVLTNLGLCAAR
V
>A0A5N9C928|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MAQETDQKNTFLQRLQDGPILADGAIGTELYRRGNFPSGICFEELSVTNPDIVRQVHLEY
IEAGAEIIETNTFGANRIKLEQNGIENVQEINQRAVALAHEARNLTGQEVWIAGAIGPLG
KPLSPLGTIEPEQAQEVFREQVQALLEGGVDLILLETFPSLQEIHEAITAVQSISDIPIV
AQLTFTEDDHTPSGDSPEDVLEALQSYDLAALGANCSGGSESMLRIVEALGPNLGVPLSV
MPNAGFPSSVDDRVAYASSPAYMAEYTGQMLDHGAIIVGGCCGTTPDHLAAMRSVLNQHS
GGTKLQSARSSTRASRKRRAAPQAIVEPTNLAKKMGNEFVVTMEVHPPRGFDVGANMQDL
RKLLSTTPIDAFNATDVPLAQARLSALAMSTLIQTRLGVEAIFHMGTRYRSLLAIQSDLL
GAHALGVRNVAVFMGDPPSMGDYPMSTSISDVTSSGLIKLIKQANTGLDLSDRPIDQPTS
FFVGCALNLEAPDMGKEFESLERKVAAGADFIWTQSVFDPEAVERSYKELGGFPLPLVLG
VLPLRSFRHAEFLHNEVPGIVIPEQMRKRMKDAQDEGAAMGVILAQELLQASYEKIAGTY
LVPAFGRYDAIAEIVASLPSNNL
>A0A835SJ27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon|TrEMBL
MSYRYEINPPKVNGDSLSDENNLELLSKVKHRVSEISSLCKGIHFTDSVLGTRRISPITA
GTLIRKNNQKIEITASLRVRDKKLALLEKLMQDAVLAGLNGVLILKGDPSPNEHTNSGLI
PSQTVKHFKELGFDKRLDIFLSLPSNPDFDKIQKKIEAEPAGFVTQVIHSAEQVSRIVEK
LKPQGFKIIPCILLPFEKNKKSAEFLKIDWSSYKENVVEFIKKIQDIAGDVLITSPNDFK
GALETLKKLAI
>A0A3E2SG17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gallolyticus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADIIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAREAAGDDAFVLGTVGALRGLKQCDLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEVELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKSLDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKEANFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDGLADLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALEHFKGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A2E1HG17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fulvimarina sp|TrEMBL
MSQVNALSNSGIRVSFEFFPPKSEKMEENLWRSIERLAPMQPTFVSVTYGAGGSTRERTH
HTIERILKETSLVPAAHLTCVDASREEVDEVVRQYRDTGVKHFVALRGDSQTGVGGKYIA
RPDGYRNAVELVAGLKKIDDFEISVSAYPEKHPESPDFATDIDMLKRKVDNGATRAITQF
FFDNDVFERYVERARKAGIYIPIVPGIAPIHDFTKIARFASATGASIPAWLAARFEGLEE
DEQTRSHVSAAFCAEQVLDLTRRGISDFHFYTMNRADLVYSICHILGLRAAAPVGEDAAA
AA
>A0A1A0TRV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. 852013-51886_SCH5428379|TrEMBL
MQFGPCGGVRPDGQCEMRPGPCAFDGIVTWSGAVPPPAPAPEVPLVLADFSCTPFDEDDA
AATAALLASSCDAVLVGEHQNRPDFPPTLMGRLLLDAGVTPWLTLSCRDRNRVVLEQELR
GLGSIGVRTVFCVTGDGRAYDVRPDVTQTFDLDGPRLVSLAASVGMSPAVPETPTAPPVS
LRPARLVEKQRAGASMGVLNHVPYPEMVAEFMAGARAAGLSIPVIAAAAVFTDVESAAVL
QGLPGLELDARVVEEVLAASDPVAAGIDAAVAEARALLAVEGIDGVNLSGSASASGTRVG
AEIKAEVGRRIREEVLS
>A0A3D0F7I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rikenellaceae bacterium|TrEMBL
MTVIEKINNAKSPLFTFELLPPLKGHSIDKIYASIEGLLEFEPAYINFTSHRNETLYRER
ADGTLERRVARIRPGTIALAAAVKYKYNITVVPHLLCGGFTKEETENALIEMNFLGINDV
LALRGDPVKGTRMFIPERDGHRNTNELIEQVVNLNKGRYLDSSMESASPTSFCIGVAGYP
EKHFEAPNLEVDMAYLKQKVDAGAHYIVTQMFFDNEKFYRFRDLCHKIGITVPIIPGIKP
ISALNDIKLLPQTFNIDVPQDLFKAVVKCKDDKEAREAGIEWATMQSKDLIKNGVPGIHF
YTLGRSDNVARIVKSSY
>A0A496CJT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. AF17-3|TrEMBL
MKVIDLINGSKTTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQNTDLYHEHATDLQEQVNNFNKGIAVDGSTFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVERCRAEGIDVPIIPGIKPV
VFKNQLTVLPKIFRSDIPEPFATELRKCKNDDEVKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMATDSVYKVAKEVY
>A0A4Q0RNX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium guangzhouense|TrEMBL
MSGAMTETTTPAAANGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVT
YGAGGSTRERTHSTISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRG
DPAGGIGTPYASHPDGYQSSADLVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKA
KVDAGATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRAGTTV
PDWFAAKFEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLG
IRAKSAQKAA
>G9QLG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus smithii 7_3_47FAA|TrEMBL
MTIYLDKQVNQKEFTITAELVPPRHWNPRSIIEKAVLFRGYVDAVDISDNLLAVARMSPA
VCAFFIKQIGVEPIVQINLRDRNRLGIQSDLLGLAALGISSD
>A0A0Q6P935|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. Root102|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETAIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
SYRPHPGGYENGAELVAGLKAIANFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFRQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
GSAAA
>R6X8U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phascolarctobacterium succinatutens CAG:287|TrEMBL
MRSEKIIDILKNGKIHLSCELFPPKQGAELQNSLEIVNKIAASKPSYMSVTYGAGGSTVG
YSAALAKKVEDNGMPALAHLTCVKADEAKLAEVLGQLQGFGVKNILALRGDIPADMHGEE
IGSFAHASELMRFVKQQGDFCVGGAAYPEGHPESGSLEQDIENTKYKVDAGVDFLVTQMF
FDNTILYNYMFRLLRAGINVPVVPGIMPVTNAKQIIRICQLSGTKLPPQFRAMVEKFADK
PEALKQAGIAYATGQIIDLIANGFDNVHIYTMNKPEIFAGIMNNLGEIVDK
>A0A5N9BYC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MLSDKQTISFEFFPPRRAEGIPDVVEKMKMLSAYTPDFISVTYGAGGSTQGFTEELSRIA
KADLNLEVMSHITCVGQTTEEIDHILSRLKSSNIDNIIGLRGDPPKGSDKFIPIVGGFQY
ASELINHINNNFEFCVAAAAYPESHTESTSIDTDIEHLKEKVDMGVDFLITQLFFDNNYY
FNFVERARKAGIQIPIIPALLPILNASQIRRFTTLCGASIPEQLNNKLTKIEDDDDQVIQ
LGIQYASQQAENLLSNKVPGVHFYVLNKNYSVQKILKNLNLVPH
>A0A5N9CFP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MSIFPSQSKLIEDLSNSRRNCFIACDFSPPKLDNPQGLRLATSLNPDMFSVSYNPGQSVK
LNPIFASFWIQNETKISSIFTLATGNMNPKCLEKLLLNAHVLGLTNAVFVMGDSSSKTIS
ATKALELTARMNFGLDVGNNQLDTPTNFCIGSTIDISKNWDHEISLTKKKIDSGAEFFLA
QAQFDISKVVQFLESYRDKIGTHIEVPILWGVQMITKGSSSFTSIPDYMKRDLDLGRSGL
DIALEIFDQYFAYGIDSFYLLPPFFRTGKRDYDLAEELISALTSN
>A0A5N9AWQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MAYNPGKSVRANPIMVAHWIQNNTGIPAVFTLATRDMNKRALQGILLGAQLIGLDNVVSV
MGDELKSSGKLSQKTISDFTASGFVSSIKQMNTRVDFRDRFLRHPTGFCVGATIDLSRDW
SGEIPLTRKKVTAGADFFLSQPVFDTSQPEQFMERYFKETGCRLETPVMWGVQVKVQDSV
SLVPVPDWVHNDLEQGRSGFEIALQIISEHTDYGFDTFYLVPPILRGGTRDYESAQAVID
EL
>A0A5N9EPY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MGFIQEIEETETKFGNVFITDISPPKGVNNVGYESIININSDFLLIIDSPGGSVRSAPIP
FAYKLSYQENQNVIFTLNCRDMNKLAIQSNLLGAQMLNLNNVFVVNGDKSTKQKKSAKTV
NDYTTTTLISDIVNLNHGMDFQQSKLDSIATFTVGSAIDFSKVPQINEIKLVRKKITNGT
DFFISQPCYDTSLILDFHKAYYSQYGYRIDKPIFYGVQMLSKTGRNWGFIPEDVENEMKS
NVSSLEIALKFVQELLSLGFNNIYLVPPIENGGVRDYYMAQLLIKKIRSM
>A0A8J5L3F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MDPSSKKNYVMKFEVSKVLEELRLTMDQLIDLCILSGCDYCDSIKVLDFEFPIVMINFVG
FHISRGEFIRRKNIFVCMETIMHLTCTNMPVEKIDHAMNTIKANGIQNVLALKGDPPHGQ
DKCSIFELSMEIILVSLLLEAHPDMIQGDEGATLEAYNSDLAYLKRKTLSVVLKLWKSFS
HVKILELCEIFILWLQFMQYLHMENINGKHVIYGQIQ
>A0A8J5H3T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MSLVCSLHLPSSGASLDPLPGANAGSASFIINKSDDVVFIAFSRAQAAASPSGLGRGFFE
PVSLYSSTHKLFALLGRGEEDSGGKPQPVLLQAPYEEEAQCAALCKSDKVCMETIMHLTC
MNMPVEKIDHALNTIKANGIQNVLALKGDPPHGQDKFVQVAGGFACALDLVQHIRAKYGY
YFGITVAGYPKAHPDMIQGDEGATLEAYNSDLAYLKRKTLSVVLKFWKSFSHVKILELCE
IFILWSANSPILGRTFRPIPGSASGRILGQVSISSPGQISRSIPGQASRMLLGQAFRLFP
GQVFRSSPS
>A0A7Y8YH57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kalamiella piersonii|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRAELRAIAEDYWNSGIRHIVALRGD
LPAGGGKPDMYACDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLTRFATMTNVRVPGWMNAMFD
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVIAA
>A0A7W2XAC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. RHBSTW-00901|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFRQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A1H5DPC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter alpinus|TrEMBL
MAAGFGADSGSGLGDPAEQPALPSRVEIIPTAGIVESVVAQLPAGTTVTVTCLPNHGIER
TVAASLELAGHGYNVVPHLAARSIGSREQLASILRDCRAAGIAEVFAIGGDKAQAAGPYD
SSDVLVRDIAELGSGNFRIGVAGYPEGHPNISDQQLLDSLRAKADVADRIVTQMCFSAEL
IGTYAAMLRTEGITIPVWAGVAGFVPRTKLISLATKIGVGSSLRFISGKGALGLRLMGGT
RYNPDALVAELTALPTPPAGIHLYSFNNVGSHAPVPA
>K6AY31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. D25|TrEMBL
MKVIDLIRNSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQKPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNDKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A0Q6LKJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobacter sp. Root29|TrEMBL
MKRVPVSLEFFPPKTPEGVVKLAAVRQQLYALKPSFCSVTYGAGGSTQDGTLAAVQAILA
EGVEAASHFTCVGADRASVRAKLEQFQAAGIRRLVALRGDLPSGYGGFGEFRYASELIAF
IREATGRQFHIEVAAYPEMHPQAKSPQADLQAYVEKVKAGADAAITQFFFNADAYERFVE
DSRRLGADIPVVPGIMPITNASGIIRFADSSGAEIPRWIRLRLQSFGDDTASIKAFGLDV
VTELCERLLRIGVPGLHIYTMNASTAPIEICRRLKLD
>A0A2L2NKB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont'|TrEMBL
MHHTHSPTAFNDFRRAVQAGEFLVTAEVAPPKGGDPAHMIQMAATLKGRVHAVNVTDGSR
AVLRMSSLMASVILSQNGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALTGDPVKV
GDHADAKAVFDLEAVRLLQLIRKMNQGVDCNEKPLTDGALDLFVGAAVDPQCKSWSGLQS
RFERKIEAGAQFFQSQLITDFERLEKFMDTIAAGYKKPILAGIFLLKSAKNAQFINRCVP
GVDIPQHIIDRLAKAKDPFEEGIKIAAEQVQIARQLCQGVHMMAVKREDAIASILDLAGI
APVNQLVSK
>A0A1Y1R5M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillales bacterium LUC14_002_19_P2|TrEMBL
MTTAAVTPNSPTVSFEFFPTKTEEGAAKLIATAQKLTAANPEFFSVTYGAGGSTRDRTRN
SVYNIRETTSVPTAPHLSCVGDSKEDIRTLLTRYQQDGIQRIVALRGDLPSGMGRFNSGD
LQYANELVAFIRSETGDHFHIEVAAYPEVHPQANSMEVDLQNFERKVKAGASSAITQYFF
NADSYFYFIERCRSLGIEIPILPGIMPITNFTKLARFSDGCGAELPRWIRKQLEAYGDDS
ASIRQFGEEVITRLCERLLAGGAPGLHFYTLNQAEPSLKIWNNL
>F8DZZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium resistens (strain DSM 45100 / JCM 12819 / GTC 2026 / SICGH 158)|TrEMBL
MSAINRQVAVSSSLNLTTPGRVPFSVEFMPPRDDAAETRLWNAAEAFHDLGVSFVSVTYG
AGGSTRARTLRVAEKLATKPLTTLVHMTLVQHTVEELQDILRSYAELGLTNLLALRGDPP
GDVNAEWIPTEGGLEYAHELIDLVRAMPECEHFDIGIASFPEGHFRAGGLENDTKYTLQK
LRAGAEYSITQMFFDVDHYLRLRDRLAKADPEHGSKPIIPGLMPITSLRSVRRQMELAGA
SLPKALEKKLLNAAAGDEEKNRAAIREVGIEVTTEMAERLIAEGAPDLHFMTMNNVRATQ
EVLHNLGMAPAWGPGLGHDMVR
>A0A421BSQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinirhodobacter hankyongi|TrEMBL
MTTPTVSFEFFPPQTLDASFRLWETVQALAPLKPGFVSVTYGAGGTTRKLTHEAVATIHK
NYGLNVAAHLTCVDATKAETLEIVDAYAEAGVTEIVALRGDPPKGATHFTPHPQGFASSV
ELIEALAADGRFTIRCGAYPEPHPEATDALADVRWLKRKTEAGASSAITQFFFEADTFFR
FRDACVKEGITAKIIPGILPIQSWKGAKGFASRCGAAIPAHVAEGFEAAIAAGREREHAT
DLCIALCEALIAGGVGDLQFYTLNRPQMTQAVCAALGVVPAAAAA
>A0A1I7N6S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia crocina|TrEMBL
MIDDDHRASRKTADERPDLQISFEFFPPKTDAMEERFWESIHKLAPLKPRFVSVTYGAGG
STRERTLRMVRHITSDAGVPAAAHLTCVGASRDEVDEVVRGFAEAGVKSIVALRGDPPEG
VGKPFVPHPQGYQNAADLVAGIRRLGDFDISVAAYPEKHPQSADWDADIDNLKRKLDAGA
NRAITQMFFRNADYLRFLERARRAGITAPIVPGIQPIHSFKQIAGFAERCGASIPDWLAD
RFEGLGEDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRPN
>A0A8H8S9L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnellula occidentalis|TrEMBL
MEKITDKIAALPPGTSYFSLEFFPPKTAMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
AEKSLELAELCQRELGLTTCLHLTCTNMSKELVDKALEDAKALGVRNILALRGDPPRSSE
YGTETAVEAEEFEWAIDLVRYIRKMYGDYFCIGVAAYPEGHADESHPEGQSMEHDLPYLV
EKMKAGADFIMTQLFFDVEAYDAFEKRLREHESGAFKTIPIIPGMMPIQSYQMIKRTTKL
SHAKMPPSITERLDVVRGDDEMVKKIGVDILSEIITHIKDEPGPGPRGFHFYTLNLEKAV
SFILERTDLIPASPPDPDSEYAIIDLPLQPLSINGSEGSQKKRSRRQSSIGSDPHNRVII
NASLTSHPSYEATATEAGQPALAVNTRANTLAISEGEGTLGREATWDDYPNGRWGDARSP
AYGEIDGYGVSLHMSTNQAVKLWGYPTSVSDITALFIKHIEGSIPAIPWNEEGLNEETAT
IKSQLLALNQKGWWTVASQPAVNGVRSSHAVFGWGPKNGFVFQKAFVELFIPSSSFPSLL
QKLEDSEEVSYYACNAQGEFKSSGDGGANAVTWGAFPGKEIVTPTIIEEVSFRAWAEEAF
GIWAEWGRVYGRGREESRAVVEGCMGDVWLVNVIHHGFVEKDGLWELLLN
>A0A6I3ISK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arsenicicoccus sp. MKL-02|TrEMBL
MAPGSSFLAPRDLSGISIPDMLRAEGTSFSFEFFPPKDDESEQVLWEAVRHLEKKRPSFV
SVTYGAGGSTRDRTVRVTRRIAEETTLLPMAHLTCVASSRAELRSVVGAYADAGIRNVMV
LRGDPAGGLGAPWVAHPEGLDHADQLVALVRDLGGFTVGVAAFPDKHPESASLEQDADVL
VAKQRAGADFAVTQMVFDVDNYLRLRDMVTSRGGTLPIIPGLMPITSARQVARMAELSGS
ALPVAVTSRLEAVGDDAEAVREVGVEIATEHAARLMAEGAPGLHFYTMNRSTATLEVFAN
LGH
>A0A7U3UPK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SN-593|TrEMBL
MNPLSTAPTAAGTSLLEDFSLEMTGKDVSKLEDAAELIPPGTRINVTFLGNEDLRMRLEA
ARAVKRLGFRPVPHISARRLGSRADFERFLTGLRDDATGAEVFAVGGDPARPEGPYADSL
ALIESGLLPGHGVRHVGISGYPEGHPAIPDDVLRAALRDKSAALAAQGLDGGVITQFGFD
VDPVLAWVERVRDEGITLPVRIGVPGPAGVRRLMGYAARFGVGTSASIAKKYGLSLTNLM
GTAGPDRFLHALADGYDPARHGDVKIHFYTFGGLRATSEWVARFRKEALA
>A0A7D8B4Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio spartinae|TrEMBL
MGYSYAGHIDALNQNISELSGDLNVSFEFFPPSSPKMEETLWNSVQRLKTLQPKFVSVTY
GANSGERERTHAIIKEIKSRTGLVAAPHLTCIDASREALSQIADDYWNNGIKNIVALRGD
IPPGGGKPEMYAADLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ISQFFFDVECYLRFRDRCVSAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPGWMNQQFD
GLDDDPVTRQLVGASQAIDMVRILCREGVKDFHFYTLNRAEMTYALCHTLGIRPQA
>A0A7C4SPB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurococcaceae archaeon|TrEMBL
MSNCPKNMLNGPCGGYRGTQCEVRGECVWVKVYISLHDHSRRYEVFTKVNLKPYFKLRSY
YPPSRRALSKFMTLLNRGKAVVYEVFSQPLTQDIPNLLNMLSKLSDYVDVYTIVDSPMGL
KTYDQLALALLIKNYLKEHDVMINIASRNKSVDEVTSYLLTTLNCDIRNYLIVTGDWPKK
HVNTFFEVDSTQLVYLSRILSDLGIDYSGRQVNLGSRPAHIGVVANQYSNYLDLEVLRCV
RKLKAGAEFIVTQPVYDVDRFKKFARSLRNYDQDAKLLATYAVIDDVERLNILKALGIVL
DELERERIINLLRSNDVIDANERMFKEVLEGVKDLSSGFYISTYGNNEVTLKFLKRVRTH
IMSL
>A0A163CP05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenobacter luteus|TrEMBL
MSQNRTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPEFFSVTFGAGGTTRDGTLAAVLEIQ
GEGHAAAPHLSCIGSTRDSIGAILQEYRNHGIRHIVALRGDIPSGMVGIGEFRYANELVA
FIRETHGDWFHIEVAAYPEYHPQATSAAADIDNFVRKVEAGADSAITQYFYNADAYFHFV
DAVRAKGVTIPIVPGLMPIANFSQLARFSDACGAEIPRWLRLKLQAYGDDIASIRALGLD
VVTELGDKLLSGGAPGLHFYTLNQAGLVSTVWQRLGL
>A0A519HKA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MSIAPRSLAEARALLLSPLGPIARAGQDQSRPRVSFEFFPPKSDEAEANLWKAVTRLAPL
EPEFVSVTYGAGGSTRERTHRTVERILAETSLTPAAHLTCVEASREDVDAVVEGYRDAGV
RHIVALRGDPPGGNGIGGVYVPRTDGYANATELTAAITAKGGFDVIVGCYPEGHPESPST
DHDIDVLKAKVDAGATRAISQFFFDIDAFLRFRDRVRAAGITIPMSPGIMPVTNFNGLKR
MSAACGAAVPDWLAAHFDGLDDDPETRKLIAASVAAETCARLQEEGFADFHFYTLNRADL
VYAICRVLGVRETKAATV
>A0A1W6B4P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea alhagi|TrEMBL
MSFFHANQREALNQSLAELNGRINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELRTIARDYWENGIRHIVALRGD
LPPGGGKPELYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPGWMNSMFA
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAQLVA
>A0A4R9GB13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira fletcheri|TrEMBL
MKKILEIYNNAKGPVYSFEFFPPKTDEGEGKLTETLRELSRLQPGYITVTYGAGGSTRDK
TIRLTSDLAKQFDVPAAAHFTCVGGNREEIRSILGEIYASGIRNLMALRGDPPKGQGEFQ
KAEGGFGHASELISFIKSEGFDFCIGGACYPEKHPQARSLEEDVDNLKKKVDAGASYLVS
QLFFKNEIFESFLGLVRKKGISVPVIPGIMPITSFSQIERFRAMAACEFPAELLSDLEEV
RNRPEEFYRRSLNFSVRQCRELLSLGSPGIHLYTLNQSHASYDIVRELEN
>A0A374EMQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM31-15AC|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A243QBW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia lacunae|TrEMBL
MRPAPYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFFPPRDAEAESRLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSVAELRALVGAYADQGIT
NILALRGDPPGDPLGEWVAHPEGVEYAEQLVRLIDTLGDFHVGVASFPETHHRSPDIDHD
TRTLVDKLRAGAEYSITQMFFDVEHYLRLRDRVAAADPEQGLKPIIPGIMPVTSLATARR
MVELSGSVIPADVEERFAKAAGNGAEEDRASVRAVGIDFATEMAQRLVAEGAPCLHFCSL
NFAKATTEVLGRLGVDVDAALHVPV
>C5GI01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces dermatitidis (strain ER-3 / ATCC MYA-2586)|TrEMBL
MEKISDKIAALPRNANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRSLVDHALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTYAVDLVKYIRRTHGDHFCIGVAAYPEGHSDESHPEVQDPARDVPYL
VEKTRAGADFIMTQLTYDLEAYKRFENMLRTHESGVFKDIPIITGLMPIQSYHILTRTTK
LSHARVPPNIMARVEEVKSDDESVKRIGVDILCEIVNGLKEIPCPGPRGLHFYTLNLEKA
VAFTVERCSLIPPSSEPSSDSEADLDTAVSMVHGQLNNIVRMSKRRASSINSQPHNRLIV
DRPSDGRGSSQASTTHETQTLGAGMPALNPPHRATTLQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVTPAVARRLWGYPTTKEDINTIFQRHVSGDLHIVPWSEGGT
QDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAF
VEFFCTAHDLKTILKPIFENHGHDELAWFATNAAGDFESSSPPTDDSANDYSGPVDVYLD
SNATAGGTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRVFPRGSPTEK
LLDQLKNDVWLVCVVGQKYGAGCQSREAAETEGKLLWKLLAGQATEADSTNKH
>A0A5N8TD55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinivibrio sp. VYel4|TrEMBL
MSYTHAGHIDALNQNIADLDGDINVSFEFFPPSTPSMEETLWNSVHRLKALKPKFMSVTY
GANSGERDRTHDIVKSIHDQTGIAAAPHLTCIDATEDELRHIARDYWQNGIRDIVALRGD
LPSPEKKPDMYAVDLVRLLKEEHDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAKMTNVRVPQWMHKQYQ
GLEDDPVTRQMVGASIALDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPLTVTP
>G2WPF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain Kyokai no. 7 / NBRC 101557)|TrEMBL
MSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKT
LALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVE
AGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
AILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETVANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWET
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNNPVKQTTIIEEESFKA
WRDEAFSIWSEWAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETDELWEMLLDQA
>A0A6A6GEM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elsinoe ampelina|TrEMBL
MHISPKLRQSAEEQRPTFSFEFFPPKTAQGVQNLYDRMDRMHDFGPTFIDVTWGAGGHLS
HLTTEMVKVAQSVYGLETCMHLTCTDMPRSKIDEALRDAYNAGCTNILALRGDPPREKEK
WEAASGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDHRDQELLVEHLKEKIDAGGTF
VVTQMFYDGDIFIDWVKKCRAAGINVPIIPGIMPIHTHAAFLRRANWSKCHIPEAWIKAL
EPVKNDDAAVREVGKGLIADLCRQLIDNGIYHLHFYTMNLAQASRMVLEELGIMPCAESP
VEKPLPWRQSLGLKRREENVRPIFWRNRNRSYIARTQEWDEFPNGRWGDSRSPAYGELDA
YGIGLRGTNEQNRKLWGQPKKLRDIGDLFARYIEGKVESLPWSESPITGEADVLRKDLAD
LNRRGILTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELVSELITRIERDP
DVTYFAVNQQGDLKTNSTSEMGPNALTWGVFPGKEIVQPTIVETVSFMAWKDEFYRLGHD
WSRCYDNDDPARYLIDGMMKEWYLVNIVHNDFRRERTIFPFFDGLQVPNLDKPAVVLPTD
SNGEKHERSDSALVNGHSSPNGKATPTESANGSNGVGLGIRAKN
>A0A524Q5Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|ANME-2 cluster archaeon|TrEMBL
MNFAQKLKSGKFVITAEISPPKGPDMSGVLKDAVLLRDLVDAVNVTDNQRAMMRMAPVAL
SHKLWEMGIEPIMHVTCRDRNRLALQSDLLAAQAMGVSNILAMSGDYPTMGDQSGTKPVY
DLDSVQLLQLIEKMNNGIDFQDGTIDSQTSFIAGAVANPGSRPLDVQLIKLNKKVEAGAS
FIQTQAVFDVGAFMEFMDAIKYIKIPVIAGIIPLRSARSARFMNEKIPGVRISEEIIKRM
ELASDPTAEGLIIAAETIQQIRPVCQGVHIMPIGGHENTRHLLELSDQE
>A0A7G2U3A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseobacter sp|TrEMBL
MTSPAVSFEVFPPKSVDASFRLWDTAQALAPLAPRFFSVTYGAGGSTRDLTHDSAHVLRR
TSGLPVAAHLTCVGASKAETLEVADSFAEIGVTDIVALRGDPENGAPTFTPHADGFADSV
ELIEALAKTGKFTLRVGAYPEPHPESXDQAXNVEWLKRKFDAGADEAITQFFFETETFLR
FRDACAAAGITKTITPGIMPVTNWKSARNFATRCGASVPAALDEAYAAAIRDDRHDLLST
ALCTEMCSELVSEGVENLHFYTLNRPELTRAVCRALGVTAQTSLSDVA
>A0A858ZR22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicycliphilus denitrificans|TrEMBL
MSLPVSFEFFPPKTPEGADKLRAVRRQLYARAPQFCSVTYGAGGSTQEGTFATVRAIIEE
GVDAASHFSCIGATKAGVRQQLAELKAMGVKRLVALRGDLPSGYGLGGEFQYASDLVAFI
RQETGRDFHIEVAAYPEMHPQARSPEADLQAFATKVRAGADSAITQYFFNADAYSRFVDD
ARRLGVEIPIVPGIMPITGSSQLMRFSDACGAEIPRWIRLRLQGFGDDMASIRAFGLDVV
GRLCEQLVRAGAPGLHFYTMNQSAATLALCERIGC
>A0A6L8GKH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. SB0672_bin_10|TrEMBL
AALRRFCRELAAPLGLPVLAGVFLLKSGKNARFINRMVPGASIPDAAIARLDASRTPRAE
GLRMAAEQVAAVLEIAQGVHLMAIKAESAIPQILDLAGIPPLAPPMVDSVGPRSLAVEPR
>A0A6P0LER6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO3H5|TrEMBL
MTNPTKNSFRTAVESGEFLITAEVAPPKGGNPAHMVQMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQQGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFEK
KLEAGAEFFQSQLICDFDRLEKFMDQIAAGTNKPILAGIFLFKSAKNANFINKKVPGVNI
PDEIIDRLAAADDQLQEGIKIAAEQVKIAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSPVNDLVCK
>A0A258LJS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mehylophilales bacterium 35-46-6|TrEMBL
MKSHQEKLAFSFEFFPPKTAEGMDKLREARKELAKFNPEFFSVTFGAGGSTRDRTMETVL
EIQREGYQAAPHISCISSSKAEIRDLLHTYQSHGIKRLVALRGDVPSGEVSAGDFKYAAE
LVEFIRAETGDHFFIEVAAYPEFHPEAKTPTADLQNLKRKMDAGANSAITQYFYNSDAYF
RFVEQCDSFGITMPIVPGIMPINNITQLARFSNVCGAEIPRWLKMRLEEYGDDMASIRAL
GIDVVSELCETLMVWGVPSLHFYTLNQSATISTIINNIKD
>A0A3S4QGX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dinothrombium tinctorium|TrEMBL
MVRGNVRSNSSSSMSSSADVDSGSEDIILSASENNHNCSSKPSSYVPLIEKINQRIKSND
PFFSLEFFPPRTKEGGVNLLSRFDRMREGGPLFCDITWHPAGNPGSDSPTSSITIAGVAL
NYCALETMLHITCVNMGPDELKKHLNRAKELGIRNILALRGDLPENEEMKELYFHYARDM
VRFIREHYGNYFTICVAGYPTKHPEAASYEEDLQHLKEKVDAGADFIITQLFFESQDYIR
YVNDCRSIGIKVPIIAGIMPIQSHDSLRHIVRLSRLEVPKYILEAIKPIASNDEAIRKYG
IELATKMCREILASGTTPGLHFYTLNREVATVQILKNLGLWKKNPQKPFPWLTVPNYKRC
TEEVRPIFWANRTKSYVYRTSSWDEFPNGRWGDSSSPAFGELKDYYLFIGKSKSPLEELR
RMWGKELSSEKDIWDVFYNYVSGSINKYGIKVTRIPWSEGELNPETNLISEQLARINARG
FLTINSQPNINGADSTDPIVGWGASGGYVYQKAYLEFFTRREYAQILRIVLDKYPKETPI
AVTWGVFPGAEIVQPTVVDPVSFMVWKDEAFSLWRESWAKLYPED
>A0A5J6FRJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces viridosporus T7A|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFHPESYLRLRDRVDTAGCETPVIPEVMPVTSVKMLERLPKLSNAAF
PDALKDRILAAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQT
>A0A2A4FQM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizorhabdus dicambivorans|TrEMBL
MGSPVMAIDCDSVPDNLVHCFSIEMTGKDIDALQAAAPLLPPGTSVAVTFLPGENYETRI
AACKAVRDLGFEPMPHFSARRIQDEAEFHDFLHAVVAEAKVRRCFVIAGDAAEPEGPYAD
SMQLIASGAFEAAGIDLIGVAGHPEGHPNMTAGEATAVLRAKTDEIERRGMAALIVTQFT
FDAARTLDWLAEVRQAGIDVPVLLGVPGPAGIKTLLRFAARCGVGASASVLSKYGISIGH
LLGSAGPDRFVDALRAGIGEQHGHVRLHFYPFGGLDKTARWIADYARKH
>S2ZRT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. HPA0037|TrEMBL
MTLREKHQNGQFTITVELDPPKSSSAQKVFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNEGIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDHGDHPFAQSV
FEVDCMGLLNIAKTLNSGKDLAGNDLDEPTNFYIGATGNPGSPDLEIERQKLAAKIKNGA
HFVQTQPIYDLEQAKRYIDKMSEFNVPIMLGLIPLKSFKMATYLHEKVPGINLTQDILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>J1FJH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter sp. BAB1700|TrEMBL
MKVTEHFQNANGKTLFTFEILPPLKGENMKTLFGHIDPLMEFKPPFIDVTYHREEYVYKQ
RENGLLEKRSTRKRPGTVGICAAIQNHYKVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLVLRGDCVKSEQRFVPEPDGHTYATELIGQVVNMNKGCYLDDEQAYHNGTDFCIGVAGY
PEKHFEAPNITSDLRWLKKKVELGAEYIVTQMFFNNQKYFDFVKRCREEGINVPIIPGLK
PMTTKTQLTLLPSLFHIEIPCALADAIEVCPDNKAAAQVGVEWAIQQSKELMEFGVPCLH
YYSMGKSESVRKVAEALF
>A0A2A4FR24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizorhabdus dicambivorans|TrEMBL
MFPANILRGFSLEIIAKDIDRLEDVAPLLARGTQISITSLGNEDAGQRVRAARRIRDLGF
VAVPHIAARRVTSEAELAGIIDAFGQAGVDSCLVIAGDLPRAVGPYDDALAIIQSGLLEE
AGFRRVAVSGYPEGHPHISDPVLMRSLRDKLDALGRAGIEPVVMTQFGFSADPILAWVAR
LRRDGFAEKIRIGVPGPASLRTLLRFAAQCGVGASTKVIGKYGLATTQLLKTAGPDVLVQ
DLSNGLERAHERDVAIHFFPFGGLAKTLEWIESARAAYG
>A0A386TC70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. D7|TrEMBL
MTTPAVSFEVFPPRTVGAAFKLWDAAQALAPLAPRFFSVTYGAGGTTRDLTHDSAHVLHR
TSGLPVAGHLTCVGASRAETMEVADKFAEAGIKDIVALRGDPQAGTDKFAPHPEGFADSC
ELIEALAKTGKFTIRVGAYPDPHPEAADQQANIDWLKRKFDAGADEALTQFFFEADTFLR
FRDACVKAGIDKPITPGILPVVNWTSARKFAVKCGTPIPEWVDQAYEAAIRDDRHDLLAQ
AMCTELCSELIDEGVDALHFYTLNRAELTRDVCRAIGVTPQVDLSDVA
>A0A178ZPI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fonsecaea erecta|TrEMBL
MASQHDDRLPTLLSSLPASSYYFSLEFFPPKTPSGFSNLQARLARMATALRPLFVTVTWG
AGGSTATKSLELAEVCQRQIGLTTVLHLTCTNMKRHMIDEALEGAKEIGIRNILALRGDP
PREEYKDVTATDDSESGSGGAGTESNQEFTWAVDLVRYIRRKHGDYFAVGVAGYPEGHAD
ESHPEQGKQSVEHDLPYLAEKVAAGADFIMTQLTYDIEAYAAYEKRLRGYTDQDGKKLFE
RIPIIPGLMPIQSYQIIKRITKLSHAKLPEKIAQRVERVKTDDEAVKKVGVDILSELVEE
MKALPQPEALPRGYHFYTLNLEKSVSFILERTGLIPSISSEGSVEEKDGDSASGSDVAVD
DSQHDTPVIVTTGPMDNRDENGQQSSGFMRRRRSSVNAQPHNRVITDRRTETRTQSRRPD
SDTDPPGSGPSPNIKLTSQHSARDRGTGIPAASPSRRHSLLISEGQGSLGREATWDDFPN
GRWGPSHSPAFGEIDGYGPSLKVSPLVARKLWGYPRSREDVTELFKRHVLGELMAVPWSD
DIDPDLTSPNGASVDGSKNSSALRAETDVIRSELQSLISSKNYWTLASQPAVDGAPSSDP
IFGWGPPGEGFVFQKAFVEFFCGRDEWEQNLRPRLMKYGSDVLGWMKTDAEGVFESSELV
ARDHARTKKATLADTEKENTKPGSPLYPSDQKSAFSTSSTSPMNTVNAVTWGVFPSREIL
TPTIIEAESFRAWAQEAYAIWNEWKRCFPRGSQEAVFLEKMGKDNVLVNVVGQAFRGGHD
GGKGEGARLWRILLAEEGEG
>W9H006|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Skermanella stibiiresistens SB22|TrEMBL
MDTPLPANLAVSFEFFPPKTEKMEQTLWQAVHKLAPLQPEFVSVTYGAGGTTRERTHATV
CRLQKETGIQAAAHLTCVGATREEIDTIAKTYWDSGIRHIVALRGDPPTGVGTAYEPHPG
GYAYAADLVAGLKRAADFEISVAAYPESHPQATSPADDLDNLKRKIDAGATRAITQFFFD
VTAYLRFVERAAAAGITVPIVPGILPITNFTRAIEFAGSCGAAIPPWMADLFAGLDNDPE
TRQLVAATVAVEQCRQLHAEGIQNFHFYTLNRAELTVGICHMLGVRPRELATAPAPATAS
>A0A1M5W1I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium grantii DSM 8605|TrEMBL
MGATFFLTQPIYDEEVIEYLVKLKKQYNVTILGGIMPIVTYKNAHFLNNEVPGISIPKIY
VDRFHKDMTREQAEEVGINLAVEVANKMKPHVDGLYFITPFNRVEMVMKILNKIR
>A0A3P1BPM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Larkinella rosea|TrEMBL
MFLDKIKSGESGVLLYGITPPKAGTPPERIAEIAGKTMERLSALDIDALVVYDVQDESAR
TTEERPFPFINALDPFVYASGYLSALTVPKIIYRPAGKFSAVELSDWLEELHENRFYPVF
VGVPAPDYPVKTSLPEAYKIWSKHQDSSVIGAVTIPERHKLLNDEDVRMLDKMSCGVSYF
ISQCVFNLDYARQVIDDLAQSCNRQQVSPPTIIFTITACGSAKTLQFMEWLGIHVPDELK
EELKKSDDILEKSVRVVLDIASELTAYCLERAIPFGFNIESVAIRKVEIEASIDIANGIG
QMLKEKGLR
>A0A7X3AXI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. BIOML-A1|TrEMBL
MTKQTPSLSFEVFPPNPEVGNAKLLRALENMQELAPHFISVTASNNKYNIKETTVALANH
IQNELSIPTIAHLPAIYLSKEKVADTLHELDQVGVHRILALRGDIIPGIEPLKDFRYATD
LIEFIKTEAPHFDVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVHHATKALFEHQPNLEVI
>A0A6I5YL29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. CAP-1|TrEMBL
MTLNDPVAPLYADLAGDCHVSFEFFPPKTEKMEAQLWSAIETLTPLAPKFVSVTYGAGGS
TRERTHNTVARIAQETPLAAAAHLTCVAASKAEIGEIADAYWEAGVRHIVALRGDPPEVG
GRFEPHPDGYTGAADLVDGLMQRHPFEISVSAYPEVHPDAASAQSDLDNLKRKLDAGATR
AITQFFFAPETYFRFMDRVLAAGISADIVPGIMPVSNFAATRRMAAMCNTDVPLWMARLF
EGLDDHPAARQLVSATIAAELCRKLYEGGVRDFHFYTLNRAEHSYAICHLLGLRPKSAAV
AQSEKAA
>A0A7Z1RIS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hodgkinia cicadicola|TrEMBL
MINQTSVSFVSANSIYVKFSVEYFPPRKISNLSKMMKSDLTPKQTKLLEFNSITCSSENK
NRLNSTTFLLVVLRRLCNCSIVLHNLLTQIKCMLISDTPMFHDLGMNNMLLISGDKYTTN
KRRSDDISPYKIRRLLRKKNVFNIGTGYPDNHILCSGSFQDLFTMLLNRESGCSMHITQI
FNHMDNFLRNNLRCSMFKLGSLLPGLFISSKHPLAVDINLKCGIYLTRPVKELLESEYLD
ERAAFLFNLYRIIEIIKNDITWIQVFTLNKTRILKEIIWMLNDLTYYIRYWRLTNHNECY
AIMSDMHNAYKRR
>A0A416E0A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF34-13|TrEMBL
MNFKDYIKTHNILVDGSFGTYYAEKYHTNEAPEYANIYHKDRVTNIHSSYLDAGANLIRT
NTFATNTMSMQKDFSFVEDNIKEAVSLAKIAVKLSGKKDIFIAGDIGPVSTVSGVSNENL
INEYFNIAKTFADEGIEIIQFETFMSLDVLADVIPKIKKELGLFIMVSFSVNQLGYSASG
LSAKNLINDICAVDGVDAVGLNCGIGPYHMYNILEKIKLPEDKVLIAIPNAGYPVLTRNR
MEFNSHPEYFAEKTKELLSLGADIIGGCCGTSPEFIKSLYDIMSMDIKADKKIQKTDAAD
EKVSKRCGFLYDENGRKKDKKFIAVELIPPFNTDDEKLLESAHYLKNAGVDVLTFPDSPS
GRTRVDSVLMAAKVYRETGIDVMPHVCCRDKNAFAMRAMFMGAKINDIKNFLIITGDPVP
ASARDLVKSVFNFSSVGLMKIAQEMNREVFNENPLNYGGAINQNLINLESIINTTKRKMD
AGASFFLTQPVFSKEEADRLRKIKEETGACIFAGIMPLISRRNALFMKNEIAGINVTDEI
VNRYPENGSKEDGEKVAVELAKEIISYIDDFADGYYFSFPFNRVYLLNRILG
>A0A5Z6YZR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Kintambo|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0E1YD45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes FSL F2-208|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGEKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEIFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDAEPGERLLDKVKEGLTILVELDPPRTFDTTKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKAKIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A516IQE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas xanthus|TrEMBL
MNRAAEIALSDHAPLFAEARGDIAVSFEFFPPRTDAMAETLWRSIETLAPLRPRFVSVTY
GAGGTTRTRTHATVRRLIRETGLTPAAHLTCVGASRMEIDSIARDYWALGVRHIVALRGD
PPEAGQAYAPHPEGYANAAELVAGLKAIAPFEISVAAYPEVHPDANCPDSDLDNLLRKID
AGADRAITQFFFSAECFFRFRDRVAAKRPGVEIVPGILPVSNVGQTRKFAGQCGAAIPAW
LDQMFEGLDDLPAARQLVAATIAGELCGQLYAGGVRQFHFYTLNRAELAYAICHMLGVRA
>A0A1H8YQ63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis saalfeldensis|TrEMBL
MSSDAVGTLARSTDIEVIPMRGAVEKMLAAPAGTSFTITCSPKLGLDRTVETAEKVAGLG
YRIVPHLAARQVESAAALREIVGRLGHAGVTDLFVIGGDVEDPAGPYSCAADLLEALAAI
EHPITRIGVACYPEGHPSISEEVLDADLHRKQRHAGYLVSQLCFDAPALLRWLTRQRASG
LTLPLRVGVAGPVQIRKLIELSMRIGVGSSVRYLTKQHGMVKNLLRGNAYQPEQLLSRLG
GEAQHRALGIEGLHLFSFNQIDLATEWQRRATTPPDQAGLA
>A0A4Q3ERM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium|TrEMBL
MKVTQYLQEAKKPIISLEILPPTKGKSIDSIYSHLDPLMEFKPAFVNVTYHRAEQVYKKR
ADGNFERVEIRKRPGTVGICAAIMNKYKVEAIPHLICGGFSKEETENALIDLNFLGVKNV
LALRGDAAANEKFFTPHPSGHRNAEDLIQQIVGLNKGRYMEEDIMDGVKTDFCIGVAGYP
EKHLEAPNLDTDIYYLKRKIEFGADYVTTQMFFNNKHYYNYLQRCTENGVNVPVIPGLKP
LTNKRQLNMIPSIFNVEVPVDLYTEMMKANTPEACDQVGEEWLLEQCRDLLKNNAPVLHF
YTLGKPNVVYNVLKRLF
>A0A1B8VEP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. AU11447|TrEMBL
MSQKDRRFSFEFFPAKTEAGHEKLLATARQLAAKKPDFFSCTYGAGGSTRDRTLTTVLQL
DGDVQVPTAPHLSCVGDTKAELSALLAHYKDAGIRRIVALRGDLPSGMGMASGELRFANE
LVEFIRAETGDHFHIEVAAYPEVHPQARNFEDDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAEKLGVSIPVVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDIASIQAF
GEQVITDMCERLLEGGAPGLHFYTLNQAEPSLALWNNLKLPR
>A0A2E0VX95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospirales bacterium|TrEMBL
MKVTEYFKSAEGQTLISFEVLPPLKGGDMSAIFATLDPLMEFKPPFIDVTYHREEFIYKK
MPSGYYEKIAIRKRPGTVGICAAIMHRYGVDAVPHLICGGFSKEETENALIDLNFLNINN
VLAIRGDARSFDGKFVPEPDGHEFALDLVKQIVDMNHGRYLDDNIENGAKTNFCIGVAGY
PEKHFEAPNLKTDLEFTKAKIDAGANYIVTQMFFDNQHYFNYVKACREIGIDVPIVPGLK
PLTKQHQLTSIPRNFYVDIPAELAGEMAKAKNAEARKQVGIEWCIMQSKELKKAGVPCVH
YYTMGDADTIRQVCEAVF
>A0A349HV81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium UBA10660|TrEMBL
MELKEIYDGKTFVETGLAIHVPKISFDVFHPTSGDISKLFEELRVLKKYNPSLVSLTYGA
SGSGARFSKEDMKTILGLELNLMPHFTCVCETKNAIERNIINIENLGIENILALRGDIPQ
GVNPCSLDFEHANDLVEFVHEKTTLSIGVVGYPEGHVESPSLDVDIENLKRKVDAGASAI
FTQLFFDNDKFYRYVEKVEKAGINLPIIAGIMPIRSSAQIQKMLEMTHVDIPQNLINELE
RFPQQAKKIGAEFAIHQCHNLIDNGIQALHFFTLNHSDQVSEVLDNIL
>A0A2Y8ZTR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Branchiibius hedensis|TrEMBL
MPADRSAATSARPLIPHLLRRAEPSFSFEFFPPKDDGAEAVLWESIRRVEPVASFVSVTY
GAGGSTRDRTVRITGQIESRTTLTTMAHLTCVGTSVADLRSVIGAYADAGIRNVLAVRGD
PAGGLGTPWTPHPGGLDHADQLVELVRGLGDFTVGVGAFPDRHPESASLAADVEVLVRKA
DAGADFAITQMVTDVDTYLRLRDDVAARRPDFQIVPGLLPVTAYGQLQRMTKLNGQPLAQ
AVLDRLEAVRDDPDAVRAEGIAVCTEHAQRLLAEGAPGVHFITMNRSTASLEVVSNLGQP
AEISAAS
>A0A2D6NMU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacteraceae bacterium|TrEMBL
MEAPLFSGLPGDIEVSFEFFPPKSDKMGETLWQSVETLAPLGPRFASVTXGAGGSTRXRT
HQQVVRIQNEAGIPAAAHLTCVEATREQVDDXARHYWEEGIRHIVALRGDPPDGQSRYSA
HPGGYANAAELIAGLKKVADFEISVAAYPEVHPDSSDRKADLDNLKAKFDAGATRAITQF
FFEPECFFDFRDQAAAAGIKGEIVPGIMPVMSFAAVQRMSGLCGTAIPHWMEGLFEGLDE
RPEARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKA
>A0A0K8QH76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Hiyo1|TrEMBL
MFPTRIEIIPSAGIVEKVQAAVPLSTTLTVTCLPHHGIARTMEASIKLSLLGYTVIPHLS
ARGLEHRAQLSGILRDCEAVGIREVFAIGGDGPQGSGPYRSSLPLLADIAEYTGGSITAG
IAGYPEGHPSVSGLDLLDALLAKQHLATHVVTQMCFSAPTILDYAALLRREGVELPVWAG
VAGAVPRTKLLALAAQIGVGTSLKFLSNKGTLARKLLGGDKYSPEGLVSEIMAHPDGISG
IHLYSFNRLDMPIWERSDLPDPEASEAASA
>A0A7C6V7M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MFISEFYRSKKPVVSLEIFPPKKDNPVESIYNTIEELSALKPDFISVTYSAGGVGTSEKT
AEIASAVKNKYGIEALAHMTCIRLDRAQVASFVENLKQNNIQNILGLRGDIPEGLDPRDL
PGDFRFARDLIAEISGNYPEICIGAAAYPEGHIECESLEKDIEHLKLKVEAGAKFLITQL
FFDNELFYRFYEMALKKGVNIPISAGIMPILSKSQIQKMIFMCGASLPAAIVKILNRYEH
DPEGLIDAGIEYSCRQINDLIDNGVDGVHIYTMNRPEIAKRSIAAINRR
>A0A6A6NVA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lineolata rhizophorae|TrEMBL
MERITDRIAALPPGAAYFSLEFFPPKTQMGFANLQARLERMARALRPLFVTVTWGAGGST
AAKSLELAELCQRQLGLTTCLHLTCTNMDRTLIDEALEQAKALGIRNILALRGDPPRSEE
YREEGLAAENDSNREFQWAIDLVRYIKKQHRNYFCVGVAAYPEGHSDQSHPEHQDPLFDL
PFLIEKAKAGADFIMTQLFFDVEAYKKYEAMLRNHESGVFKDIPIIPGLMPIQSYQILRR
TTKLSHAKLPQEMLARLDAVKGDDEAVKRVGIDILSEIVEDIQATSGGGSHRGYHFYTLN
LEKAVSHIVERCSLIPPDEEEEGNDEAVIVDGSSGQISPPAEDGAHFRDRRRMSSVNSNP
HNRVVVERVSSSSNPSWEAPEDEVGVPRDKINSRANTLAISEGEGSLGREATWDDYPNGR
WGDARSPAFGEIDGYGVSLHVSIPQAIWLWKYPVTHDDISELFQQHILGKLEAIPWSEEG
LNPETITIRDQLLRLNSKGWWTVASQPAVNGTKSTDPVFGWGPKNGFVFQKPFVEFFLPS
SDWARLRKAFEQHEDEITFFAGNNAGDVAASDAESVNPVTWGTFHGKEIITPTIIEAVSF
RAWLEEAFSIWREWQRIYPARSPTAKLLGKIREDYWLVNVIHHGYVQKNALWDLLLVA
>A0A1H9H5U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema bryantii|TrEMBL
MTKTIFSFEVFPPKKTMPIDTIFSTLDELKGLSPDFISVTFGAGGSENCNNSVEIAKHIK
NVCGVQSVIHMPCLNMTRQDAQYVLEQFQNAGIENILALRGDRVEGKEPANDFHHASDLI
QFIQEFDSKRTDGKQFKIFGACYPELHPQSKNVYDDIDYLKKKVDAGATHLLSQLFFDNA
QFYRFLERCQIKGINVPIEAGIMPATNKKSIERMVSMTNAVLPKKFTDMMDRYADHPEAI
RDAGIAYAIDQIIDLVTHGVQGIHLYTMNNPLVARKIYEATKSLFDVPPIIK
>A0A354MRE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MRITELFDNGEFVVSAEVGPPKGIHIDGMVEEAKKYLTRVHFVNVTDNQSSVMRLGSLAT
CKVLKDAGLNPIFQLTCRDRNRIALQSDLLSAAMLGIDNILCLTGDHTKLGDHPQAKPVF
DLDSVSLLHAASTLETGVDLGGNALVGVPPKFAKGAVVSPCSDSVDAQLVKMERKVKAGA
EYFQTQAVFEPEKFIKFMEEAKQFGKPVQVGIIIPKSAGMCKFM
>A0A2G4GAR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobium sp|TrEMBL
MARIGDLLAAGRTFSFEFSPPKTTAGSMSLGRTIAELESLSPSFVSVTYGAGGSTRENTR
DTVLWIERETNIPAMAHLTCVGHTRTEIEDIIATYMAAGIQNVLALAGDPPKDPADARPS
DYVYATDLVEHLREIADLSIGVAAHPEGHPRSPDLATDRRLLAEKLKVVDFATTQFFFDI
DHYLSLVNDLADLGVTKPVVPGIMPCTNIAQVERMAELSGAAFPGWLRERLESGTSPEDV
RRIGVEAATELCSQLLAAGAPGLHFYTLNKSTATREIYAQLGLPVA
>A0A292YMD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Effusibacillus lacus|TrEMBL
MYQIHGLREKLSLGKSVVTVELEPPKGADPMPTMLTAKHLRGYVDAVNIADSPMATLRMS
PIALSHIVQQDLGLEAIFHLTCRDRNILGLQSELLGAAALGVRNILTLTGDQPSRGDHPE
ARGVFEVDAIGLVKIAKRLNEGSDLAGKALNAPTDFFIGGAANPGADDQEVEFSKLRAKV
EAGVRFVQTQPVFDVETALRYQERVVKEGLPVYVLYGILPLKSAKQARFLNEKVPGITIR
REIIDRVEAGGREAGVEIAQELYYALKPHVAGVHLYPLNNLQTVYDVLEIKVEPSIAL
>A0A380TTY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus lignieresii|TrEMBL
MSYAKEIDHLNHTLADLNGNINASFEFFPAKNEKMETLLWDSIHRLAPLKPKFVSVTYGA
NSGERERTHSIVKRIQQDTGLLAAPHLTGIDATPDQLREIAKDYWENGIRHIVALRGDEP
AGYTKQPFFATDLVKLLKEVADFDISVAAYPEVHPDAKSAQSDLIYLKQKVEAGANRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIIPGILPVTNFKQLQKMAKITNVKVPHWMHKMYEGL
DDDQTTRNLVAASIAMDMVKILSKEGVKDFHFYTLNRSELTYAICHALGVRPN
>A0A357D0C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MSIADIFNTKKPVVSFEIFPPKKNGVLVNADETIKSLKKLNPDYISVTFGAGGNSVNAMT
WEIARSIRENFKIEPIVHLTCLSHSKEDIDEILEKLKKYGLYNILALRGDENPNAAAKED
FRHANELISYIKSRGDFSVSAACYPEGHSESPNLVQDTIYLKKKVDAGANHLISQLFFDN
NFFYSFLDRARNAGINVPIDAGIMPLTSKKQIERMVMLCGASLPAKFKKVLDKYEDKPDA
LLDAGIAYALDQVIDLITQGVDGIHLYTMNNPIIAERIYNGFSSLIDL
>A0A1I3HYF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema bryantii|TrEMBL
MIFESDLTKKTIFSFEVFPPKKTMPIDTIYSTLDELKGLSPDFISVTFGAGGSENCNNSV
EIARHIKDVCQVQSVIHMPCLNMTKQDAQYVLEQFQQAGIENILALRGDRVEGKEPSGDF
HHASDLIQFIKDFDEKRTDGKYFKIFGACYPELHPQSKNVYEDIDYLKQKVDAGASHLLS
QLFFDNDQFYRFLERCQIKGINVPIEAGIMPATNKKSIERMVSMTNAVLPKKFTDMMDRY
GDHPEAIRDAGIAYAIDQIIDLVTHGVQGIHLYTMNNPLVARKIYEATKSLFDVPPILK
>A0A1H0TQP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. ok909|TrEMBL
MSPPSLIDPHPNLAGAAPVALSYELFPPRSAAAAESLWTTIGELEATDPDYVSVTYGASG
SNRSTAVELINRLVQETTLRPLAHLTCVGNSPEELAEIIGELLDVGVRGILALRGDQPKD
GATPPPGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHAEQYADLLTRARRAGVTIPIIPGVMPLTSLRRLARLGELTGVE
PAPELIERLAAADTDAERTRIGVSATVDLANAALDAGAPGIHLYTFNEHAAALDVLDKLA
LPRPRTGNRQGGNRHSGGRINASRRAAAHQLAS
>A0A3C1BYK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MGEVRPDEDAENGWQEERKMSVMESLSRHNTLSFEVFPPRTEAGRRELLEPDGVLDRLNR
ESPDFLCCSYGAGGADAGKNLEVLDAVVSAGRSQAMTQLTCAGNTAEGIREQLRNYRGRG
VSCVMAIQGGEGRMSWGLSDEAELVKLIRREFGNEFLVAADGAPEGEPLGSSLEGEINRL
KAIQEVGADFLITRLCWDMDIFHIWLDGIRAAGITLPVMAGVAPVVDQAATIRTALATGG
CAIPEELCRLLSDYWIYPNPFVKDPFDGEVERKRTQFREAGAAYTVRQIRLYRRWGVDGI
HFLTQNRAEDVLAIARAARDTSF
>A0A1V9Y428|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thraustotheca clavata|TrEMBL
YLPIQNYNSFLKFTNWCKTSVPDHIGQALNSIKNDDAAVKKYGIQLAIDTCRKLMAQQLS
LHFYTMNLASSVRNVLEGLNLIPRRHERDLPWGVPMLRRKDGSGDKIEQVRPIFWSNRAS
SYVARTSEWDDFPNGRWGDRSSPAYGELSEYYLAYKRPKVARELVWGTPLTEQDVWSIFV
KFIEGSVKTLPWCEQGLSGESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGK
GGFVFQKAYVEFFVPPHLMDRLLTALKDYPNLSYHAFSANGTEYTNAPGPSVTAVTWGVF
PNQEIIQPTVVDSASFAAWKDEAFELWMSQWASAYSTDSVSHQVIKNVYDTYVLVNIVDN
DYTNEDSDIFKIFARVITEGMTKDDLRGRVLELEEKNEKLHETVAKLKIIQSEASRELKE
THQELSASREENARLKTQLRELRSRLALSAI
>A0A1H8QRL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas pseudopalustris|TrEMBL
MSDVLQHIPAISFEFFPPKTDEMERTLWQAISRLAPLTPRFVSVTYGAGGSTRERTHSTI
ARILRETHLTPAAHLTCVDAPCADVDEVVERYYDIGVRHIVALRGDPSSGLGGAYTPHPQ
GYRSSADLVASIKRRHPDIEVTVSAYPEKHPESTGFDADLDMLQAKVDAGATRAITQFFF
DNDLYFRYLDRVRARGIDIPIVPGILPVQNFKQASNFATRAGASVPDWLAKQFEGLDDDP
DTRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGLRPQVAQKAA
>A0A354MRB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
AGMCKFMNKNVAGVHIPDALIEELQADKERTKAGITGVEIAARIIRACKPYCQGVHIMSL
GWESKVPALLEQAGL
>A0A3D5MMU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MTAADAAQAAAAAVAGGPGDAAAGATSGGASGGGGGCRTSSRLERVLREGHFAVTCEIGP
PQSSKSEGILKHASVLKDYSDGQNLTDNQTAIVRLCSLAAAVHVIRAGGEPIMQMTARDR
NRIAIQSDILGAASLGVRNILCLAGDHQTFGNHPGARNVHDLDSLQMVQMVRAMRDEKKF
QCGDQIKSHEPRMFVGAAANPFGDPFEFRVRRLAKKIAAGAEFIQTQCIFDMDRFEKWMR
MVRDEGLDEKVFILAGITPVKSDKALKYIRTVPGMKVPDELIKRMEGAADKKAEGVNIAV
EMIQRLKEIKGVHGVHIMAIAWESIVPEIVERAGLYPRPKVEVEEPAEAEVAVG
>A0A1W2EYE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentzea albidocapillata|TrEMBL
MTSVVERLRGESPKFSVEFLPPRDAEDEKVLWKAVRELEGLDPAFVSITYGAGGSRRDRT
IRATGRIAQETTLLPVAHLTAVEHSVAELRNVIGWYAAIGVRNILALRGDPPGDPMGEWV
AHPEGLNYADELVRLVRELGDFCVGVAAFPYGHPRSGDLDTDLKFLLRKLNAGADYAVAQ
LFHAPEPFLRMRDRVAAAGCSAAILPGIMPMLSPRGLAKIVELSGADLPLDISRRLEPYT
DDVAGFRATGIDIATEMCRRLLDEGVPALHFYTMNRSKATKEVLGRLGLVTRA
>A0A6P1AWK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium LRH843|TrEMBL
SGIMPITNASNLIRFAVGTGAEIPRWIRKQLATYGDDTASIKAFGHEVIVKLCERLIAGG
APSLHFYTMNTTDPTRQLVLDLGLA
>A0A534IJA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MYAVRQWSVRHARGLNAFYRAFESVLVPLHPLFKRLGYERLERPVAAVERTVKGLLFDCR
MCGQCILSSTGMSCPMNCPKNLRNGPCGGVRANGHCEVRPEMKCVWLEAVAGAARIPGGM
NSLQQVQVAVDRRLEGSPGHTSPGRFERVLRAGQFAVTTELDPPDSADPEEVYRRARVFD
GYVDAINATDGSGANCHMSSLAVCALLTRVGYAPVMQISCRDKNRIAIQGDILGGAAMGV
CNLLCLTGDGVQAGDHPQALPVFDLDALTLLETARTLRDEHHFLSGRKITHAPRVLLGAA
ENPFAEPIEWRAQRLAKKVAAGAQFIQTQFCFDVPLLRTFMNRVEDLGLLDKVFILVGVG
PLRSAKSAEWIRTRVPGVHIPDEVVKRLAGASDGALEGRRLCIDLIQEIRTLKGVHGVHV
MAYRQEETVAEIIQRSGVLGGRVPWNPGRDPPANTNRMASEPTPSAALEPARS
>A0A6M8UEN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwiniaceae bacterium PD-1|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELRSIAQDYWNNGIRHIVALRGD
LPPGGGKPEMYGADLVTLLREVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPSWMTSMFE
GLDDDAETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGTAASA
A
>A0A8G8QSV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMB3-10|TrEMBL
MTATPTTPPTDPDCRSSIPFSFELYPPKTDAATMALHATIDALAAARPKFISVTYGASGS
SRTSSLDVLRYIRRATIVDPMAHLTCVGSSHAEASSLIREFLDAGVSSFLALRGDPPEGL
TENDAFLGDLHSAGELVQLIHRVQAERVPYQETPIPGLPRARAVKTEREHVRIAVAAFPN
GHPRSRSTAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPV
TSPGRLRRILELSGEELPAELSIQLEVEPTLEGQREIGVSHAAALAEKLIAGGAPGLHLY
AFNQHETVLAVLDRAGALAPAQPVVSAHNPPPTHPSTSPADTRAGIHSTKDHY
>A0A6P2BDR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MATSAANSRPSPGSGPIGRKPCGPSSESSAVPALKRVSFEFFPPRDADGLARLERVRARL
DAAGPEFYSVTYGAGGSTRDRTRDLALAIHAEGRTVAPHLSIGSDAPDAVNGLLDAYRDA
GIRHIVALRGDVPSGMGNRSEVYYANELVARIRKHSGDHFQVHVAAYPEVHPDARSPESD
LAYFADKVAAGADEAITQYFYNADAYFDFVDRCEQAGVKVPVVPGVMPITNYANLARFSD
GCGAEIPRWIRKRLEHLQDDPPSLQAFGLDVVTDLCERLLAGGVPGMHIYSMNQSKVPLA
LLDRLGHPLAERN
>A0A6L8EJT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNNLETSLNEGRFCFTAEVVPPLAASAGSLLEEAGMLNGRVEAINVTDGAAARTTMSSAA
AAALLAANGMEPVLQLTCRDRNRIALCADLVGCAAFGVSNLLLLTGDDPARGDQPEARAV
HDIDSTALVALARDMSEKGILPNDREIDPPPHFIIGCADVPQQPDDRSVPPGITRKINAG
ARFIQTQLCYDIDLIEAYAGYMGEWGIAEKAGILIGLGPAASARSARWMR
>A0A661BQ82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAISADYLAGVFRPQNEIRNALRKGRFFWTIEFVASSDHVLNDDLVTVDSFVRALARRPE
VAGFSVTDRVHSDDDPDPVMMAKHIRDHAGTQPLVHWSGKDRSITDFESSLEAMSAAKLE
NMLLLTGDKLKITPVDRRPRYLESVSAIKLAKDNYPDLIIASALNPFKYREEEAMAQYLK
LGKKIYAGTDFVITQIGFDIKKFEEALFWMDTRDYRVPMVANVMALTAARSRFIRKNQLA
GVTITDSYHEFLQQEAELFPEQAPARVLRRTALLILGLRMLGYSGVQLTAIHTVDQLMTL
HKQIDYLAKKCPDRVSWNKAWQESLTLPKAFIANPVPGKAWYMSSHMVNRPSSHAPLKDR
IKYRTMKWSHSFLFDQGLGAKVLSGLVKNIQRHSKADKILERIERLIKAPLFGCETCGMC
RLAETQYICPETCPKGLANGACGGTNDNTCEFGDRECIHSRKYRIAKDANVLSQLEHWLI
PAVPDEARQTSSWPPHFRDEGPDIDKSGMDKPEPDISSDE
>A0A0K1JKL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteipulveratus mongoliensis|TrEMBL
MSVSAGRQVQSAATSIPQMLAHEGTAYSFEFFPPKDDASEAVLWESIRRIERIRPSFVSV
TYGAGGSTRDRTVRITGRIARETTLVPMAHLTCVGSSVSELRQIIGEYAAAGISNVLALR
GDPAGGLDAEWVAHPEGLDHADALVSLVRSLGRFTVGVAAFPDKHPESKTLEEDAEALVR
KADAGAEFAITQMVTDVDAYLRLRDMVVARGRELPIVPGLMPVTRYGQLQRMTALNGQPL
ADEVTRRLEAVKDDVDAVRAEGIAIATEHAARLRDEGAPGIHFITMNRSTATLEVFDNLH
>A0A7C7MFV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKNFRKALNTQDFVITSEIFLRPETDANSIKMQADILRDYVDAILITDNQSGRIHMSTLA
AGTLLIAAGVDPIVQLSCRNRNRISLLSDLLGCSALGITSISLVRGDRVPDDFQPRPKAI
MDVNATELIRIANIMRKDANIASEGNFFLGGVVTAHAPKPGWPAKNITEKVDAGAQFVFT
HTCLDMDLLRTYMQRLGETKLLWRCHVVAGIVLLSSAEDAQWVIKNRPNVIIPNDIITRL
SNAKDPEKEGIEICAEQLQELSKMPAIAGAHIIASEKLTNIPVAIRKSGLNKKNAN
>A0A6B1GQ70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGSPLSDSIQFALNQLIRGYSVETTPGASTKIPDYRLILPAGTTVYVTLLPGSTIDDTIS
VCIRLANEGFNPVPHYAARQISNRQKIASSLQRFCDEAGGTQVLVLAGSSRKPVGDYENS
MQLLETGLFDQMGISKIGVAGHPEGSPDISTQGLEDALKWKNQYAEQTDAEMYLVTQFCF
QAKAVVEWERQLAELGNKLPVHIGIPGVATIGTLLKHAAACGIGPSMNFLKKQARSAKKL
LQNSTPEQLLHDLAQHRSWNSDTTIEKVHVYPLGGLRKSAEWLEHFQSEAETRSKSVA
>A0A7C1TJ82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDSQKKYDPTFSFEFFPPKTAEGADKLRRVRDELGSLKPRYFSVTFGAGGSTQKGTLETV
LEIRQAGFDAAPHLSCIGTSREFIRELLDTYLEHGITHIVALRGDMPSGMQESGDFEHAN
ELVSFIREETGDRFHIEVAAYPEFHPQARTAQEDLANFKRKVEAGASSALTQYFYNPDAY
YRFIESCEQMGVDIPVVPGIMPITNYTQLARFSDACGAEIPRWIRRRLEGFGDDRESLLA
FGHDVVTTLCEQLLRAGAPGLHFYTMNRTEPTLSIWKDLGL
>A0A2E1JI80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAESSKTLSFEFFPPKTTLGQEKLVKTAQDFEAVKAEYFSVTFGAGGSTQQGTLDICRSL
FDSTKTPIAPHISGIGSDKDSISLTLNQYKDKGLKRLLVLRGDLPSGYGSIGDFPYAVDL
IDYINLEFEDYFEIKVGAYPETHPEAISPEQDIRYFCEKMSRNVQGAVTQFFFNPDVYFT
FVENCQKFGCDKPITPGIMPITNKDALIRMANNXGAKIPESLLQKXDSYSNEEDIQKFGA
DYVSSLVQTLLNNDAPGIHFYTINKLEPTKXIIDLLE
>A0A2E7XH36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKFDDEPLILGENLPIRPGHNSPGRLERVLRSGGFAVTAEISPPDSADPREVYERAAVFD
GVVDAMNATDGAGANCHMSSVGMCSLLTRRGYAMVMQVSCRDRNRIAIQGDVLGASAMGV
SNVLCLTGDGVQVGDHPEAKPVFDLDCMAALSMLRNMRDNHCFMSGREITSPPKVFLGAV
ANPFAPPLDYRPLRLAKKITAGAQFIQTQYCYDIKVFEHYMKEVRREGLHEEVFILPGVG
PLASARTAQWIRSNVPGVHIPDAVINRLKNAKDQTEEGIRICVEMIQMLKEIEGIHGVHI
MAYRHEHRVAEVVERSGVLEDRVPWHPGLAVAPMEESPIHERLGTVNP
>A0A1W6RKE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum zatmanii|TrEMBL
MPNASQHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVDATKEEIDGVVQSYWDAGVRHIVALRGDPAEGVG
HSYRPHPGGYAQTCDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIEALKAKVDAGADQ
AITQFFFDNEIYLRYRDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLENDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
PAVKPEAKAA
>A0A661FNE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTHFEKRSLHEALTELSLEIGVHDLDALQQHSHLLAAGGRVYVNAVAGEGTAARINAAEQ
IKTCGFRPVPHIAARRMQSEQKLDDYLAGFVERAGVNEILVIGGDLCEPLGPFSSALDVI
ESGLPAKHGISRIGVAGYPNGHPDIDTAVLNQALQEKLAACKSATIDPYVVTQFSFQATA
IIDWCRATHKKYPGLPIHAGIPGPAKLGTLLRYARICGVQASVRKMQANKDLAFELLRRA
APWEQLEAIGQYRLDTGQPLSAHLFTFGGLKETTSWLQQAAKGRKDNSDVVEF
>A0A374USP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. OM08-17BH|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGNGYHHAVELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTKEILKCKNDAETQQVGIEWCVQQCKELMEHHIPSIHF
YSIGAVDSIKEVAKQVY
>A0A502CZE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedococcus bigeumensis|TrEMBL
MALGHTSRVDRLTRQPQSIPGMLASPRPSISFEFFPPKDDAGESTLWDAIRRLESVRPDF
VSVTYGAGGTNQDRTVRVTERIARETTLTPLAHLTCVGASVAALRQVVGLYAASGVRNIL
ALRGDPPGNVGGEWVAHPEGLNHATDLVALVRTLGDFTIGVAAFPDVHPASPSFEHDVDV
MVRKADAGASFAITQMVFDAESYLRLRDAVAARRDLPITPGLMPVTNFKQVARMSELMGT
PLPEAVVSRLEAVAQDPAATREVGVQIATELADRMLSEGAPGLHFITMNRSTATLEVYRN
LDLAARTRTPRD
>A0A1X6P7Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyra umbilicalis|TrEMBL
MSAAVLVGSSDSPTTEVQKAAALPAMPDLPASLVAGNKTDPNLRQVAHIADKIRERVAEN
RTFFSFEYFPPKTASGVENLYDRIDRMARVEPLFCDMTWGAGGSTSELSLDLSGNIQKYL
GLDCMMHLTCTNMPAGKVREGLDGAKARGIRNILALRGDPPAGQEWKQCEDGFAHGVDLV
RFIREEYGDYFCICVAGYPEGHPAGSLSGAITYEQEMEHLEDKVKAGADLIITQMFYDVD
IFLQFVRDCRKRGIEVPVLPGILPIQNYAGFKRMTGFCKTQVPPSVEEALEPIRDDDAAV
KAYGIQLAADMCRRILDSGLSPGIHFYSLNLEKSVMAVVDELGLVPQTQSIRSLPWRPAT
LDKRRTEDVRPIFWANRPKSYLERTSAWDDFPNGRWGDNRSPAFGDISNHHLVGSGGLVT
DDARAASRELYGAIKSEHDVVEVFTRFFKGTLKRLPWVEASELASETVAISTPLLWLNRN
GLLTINSQPRVNAAPSTDMSVGWGGPGGFVYQKAYVEFFASPEMTDALFAAAERFPSLTL
YAAKAHSKELRTTSKCPGANAVTWGVFPEREIIQPTIVDPYSFRVWKAEAFNLWLSHWAD
LYEAEDTAKEVLKGIHDTYSLVNIVDNDFVAGDIWRIFSDVIPSTCGATKVSARSSA
>A0A520TR38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
TRVYIAHLKNEDIEPMVTAAKRLNDEGFKVMPHMPAREIKNHAMLNDWISMYQNEAGVDE
ALLLAGSSPEPAGDYDSSIQLIESGLFDKAGFKRLHVAGHPEGNKDIDPDGGVKNISDAL
SWKQEFSKRTDAEMAITTQFCFDANVVKKWADEIKKDGIDIPIHIGIAGPAKLKTLLKFS
VECGIGSSMKILTQRAKDITKLLLPYKPTQILKDLSEFKLQEPELNIEQVHFFPFGGIKQ
TSDWVEEIQK
>A0A1H8SLV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium tibeticum|TrEMBL
MALNSDARRKIGISFEFFPPKSEEMEGQLWNAVSELQDWDPDFVSVTYGAGGTTKAPTLA
TVSRFLAETPLATASHLTCVGATKDETHSVIETFRKVGVKHFVALRGDAPGGVGAPYQPH
PGGYANAAALVAGLREIGDFEISVSAYPEKHPESRDTAADIDMLKQKADNGATRALTQFF
FDNDSFERYLEKVRAAGINIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDDK
PEERAKVAADVAAEQIEDLARRGLTDFHLYTMNRAPLVSAVLSNLGFTREGARKAGAAA
>A0A151YME8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lactucae|TrEMBL
MTRRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAEDLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAEINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHD
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A2E1VG94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTAPRVSFEFFPPKTPEAEAGLWKTVERLAPLNPEFVSVTCGADGSTRERTHQVIESILT
KTSLKPVPHLTCVGAPRSEIDSIADGYWDMGVRQIVALRGDPAGGAEAAYVPHPDGYAFA
PDLVQGLLERHPFELFVAAYPETHPQAGSVDADLENLQRKVDAGGHRAITQFFFDNEIFL
RFRDRVAAMQIDVELIPGILPVTNFNTLVRFAGACGASVPTALSMQFEGLDDDPTTRQLI
AAHAAVSQAEDLGREGVEDFHFYTLNRADLSFAVCHALGVRGCA
>A0A2E1VGA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTFDPKGKPKSWSIEITPKESKTISCFSTFLDCDTKVNVTNLPKTSVTDIFATVEKLKH
DGMNPVPHITARTVIDEDDLARIVEKYATLEVSEVLIIAGNKFQPAGSFSSSSDLISSGV
FEHFGIINLGVAGHPEGSPDITQQQLEDAIDQKNHLAASRGLNIFLETQFCFDAQRIIDW
EKAIRDRGNSLPIRVGVAGPTKLLSLINFAIKAGVGPSLKFLIKERDKLTKLVHSYDPTD
LILSLAPQFSPEANTCLESIHFYAFGGFRKTAEYAQELFK
>A0A560YZ46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SJZ131|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGNHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1N6QYW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. RU20A|TrEMBL
MAIHTLYPAERGNLTLSFEYFPPKTDEAEAQLHRTVADLNVFQPGFVSVTYGAGGTTRER
SLTAVCHMIRDAGVSNTAAHLTCVGATRDEVDRVIDDFAACGVKHFVALRGDPPDGIGSA
YRPHPGGYENAAALTKALASRGGFEISVSAYPEKHPESADVNADIDMLKRKVDNGATRAL
TQFFFDNDDFERYLERVRAAGISIPIVPGILPINNFAQVLRFAGLCGARVPEAIRARLEH
LDDKAEERFHEATHIAAEQIVDLARRGVRDFHIYTMNRSPLVTAVCDLVGFARQDPSVAA
IPAPARRMAV
>A0A2E1JLF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MEVNKNIQNFLAGYSIEVTPNAAAKIDNFSDVLPKNTLVYIAHIEGTSIDEMVNTAKKLK
DHGFESMPHFPARIIKNKPILHDWISRYKNEAGVSQALLLAGGANKPYGDFDSSIDLLES
DLFNKADFKTLHVAGHPEGSKDIDPDGSNSNTNQALLWKNDFNKKTDANMAIVTQFCFEA
STVISWANQISDLGVNIPVHIGIAGPAKLQTLLRYSIECGVGASINVIKKRAKDITKLLL
PYEPNNIISDLANHKKENPSFIIEKVHFFPLGGIKTAAKWAKSA
>A0A353PB37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTAQTIQFSFELFPPRTPAGWDKLPALASALAAVQPAFFSVTYGAGGSEQNGTYDTLIRV
VEQTGIETAPHLTCIGSTRARIGALLDQYRAAGVTRIVALRGDLPATAASSEAPGELRYA
SELVAFIRETHGDHFTLEVAAYPEMHPQAANPDADFDAFRRKIDAGADGAVTQYFFTAEA
YFDFVERCTRVGITVPIVPGIMPITNHAQLTRFSAACGADIPRWIRLRLEQYQDDKAALQ
DFGLEVVARLCRALLDNGAPGLHFYTLNQAEPTLRLWQHLGLPTPAGS
>A0A3A2Z7Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus sclerotialis|TrEMBL
MERLTDKIAALPPDANYFSLEFFPPKTQMGFANIQARLERMAHSLRPLFVTVTWGAGGST
ATRSLELAEVCQRQLNLTTCLHLTCTNMSRALVDKALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKEFMYAVDLVKYIRKQHGDYFCVGVAAYPEGHPTDSYQEAQDPMRDLPYL
VEKVKAGADFIMTQLTYDLDAYMKFEQLLRNHESGTFKSIPIIPGLMPIHSYKILTRVTK
LSHVNIPQPILDSMEHLKYDDDSVKQAGVDIITNIVEGIKKTPSPGPRGFHFYTLNLEKT
VSFILENCNLIPPYTEDSDGEDTSAIATSTMDAIPKDGQPRAFTRRRASSINSLPHNRVI
VDRAQLHQAGSNESSKDSATHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAAVARKVWGHPVSHEDINTLFRRHVSGELYIVPWS
EGGAEEATGGLNPETKVIRPELLKLIDGRGWWTLASQPAVNGVRSDHPIFGWGPQGEGFV
FQKPFVEFFCPSKDYKSILKPIFEKYDHEQFAWFAVNESGEFESSLPAQPADADTIEMNP
DNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAYRIWDEWRRVFPRGSPTERLLDSTKK
DVWLVCVVGQQFGAGTEPESKEEEDETKLLWRVLAGEQ
>A0A2E6YZA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTSKRAHISFEFFPPFTSTGQKSLLKVAKRLNIFKPEYFSVTYGAGGTTRERTHETVSSL
CQFGYTTVPHLSWGADTKSEILELLDSYAQLEIGRVVALRGDLPSGLGNKQNIRYAKDLV
NLIRKNHPSWLVEVAAYPEVHPDADNQHQDALYLKEKIDAGASGCITQYFYNTDSYFYFV
DLCRSLGITVPIIPGIMPITNQAKLEDFSKKAGAEIPRWLTKRLNDYEPESEDLIQFGIE
FVSRLCERLLAGGAPGFHFYTLNKAKSSECIAENIGFLENI
>A0A2E7DIS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNIEETNKFSIEFYPPRSADGEKNLDNVHAQLTKLKPDFFSVTYGAGGSTKKGTERLVLR
YAELGSNVAPHLSFGGTDDEEVRSLLRNYKEAGIARLVALRGDLPSTEPDHQRYASELVT
FIRKETGEHFHIDVACYPESHPDSKSYEANVEYFKQKVESGANSAITQYFYNADAYFRFV
EYCQYKGIDIPIVPGIMPITNYQKLSHFSSNCGAEIPRWLRVRLEDFGDNRESLKEFGIE
FVTELCGTLLDGGAPGLHFYSMNLAGYVTKIWDNLSLSER
>A0A1G0ZJP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_50_93|TrEMBL
MKQSLKDKLASQITIFDGAMGTEIYKKNFFVNTCFDELCLTAPRVISQIHKEYFDAGADV
LTTNTYGANFNKLSRFGLGDKIREINRAAVKLARESGNENTLIAGSVGTIGKILHHEKHS
EHHVVEMLAEQIAVLEEAGADFIIFETLPSVADTHFAFMAVNKSSNIPYVMSFALEENAE
TLKGEPLQSLLNVFKDGGRKPDAIGLNCGGGPEGILSSVEKLIRMTELPIIVQPNAGVPK
NVEGRMIYMASPEYFTTYAVRFVNLGVRGVGGCCGTSPKHIRDIARSIRPLAKTAIIEKI
TIKDHEEHLQDPVPMAQKSRLAAKFAKGDWITTVEIVPPKGYDLDSTIEKSKQCKAAGID
AINIPDGPRASSRISPIVTATKIQELAGIETILHFCCRDRNLIGMQSDLLGCAALKINNI
LFITGDPPKLGDYPFASAVFDVDSIGMVTIQSRLNRGVDIGGNSIKEPTKALIGVGADPN
SIDIEREIRRTRDKAAAGAEFIITQPVFAVEPLIKFIEKIGDLNLPVIAGIWPLSSFRNA
EFMKNEVPGVVVPDSIMERMAKAKTKEEQRSTGICIAKESIEKIRSYIRGIQVSAPFGNV
QTAIDVIKS
>A0A6M4FWJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. PGE1|TrEMBL
MSAQEHPLGISFEFFPPNTEAGREKLAGVRDALAARGPRFFSVTYGAGGSTQDRTLTTVR
QVRESGISTAPHLSCIGSEKQPLRELLARYREEGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFERDLENFARKMQAGANLAITQYFFNADAYF
HFVERARALGVEAPIVPGIMPITNYAKLARFSDACGAEIPRWIRKQLEAYGDDSASIAAF
GEEVISRLCQRLLDGGAPGLHFYTLNQAEPSLKILDNIVG
>A0A855FKQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snodgrassella alvi|TrEMBL
MSFTPLSFEFFPPRTEEGRRKLAITRKQLSQYQPEYFSCTYGAGGATRAGTLQTITDIMN
EGVAAAPHLACIGASREEMTSLLQTYKNMGIRHIVALRGDVPSGVGFGHQGLRYANELVG
LIRQEFGDWFHIEIAAYPEFHPQSRSAEDDINHFVRKCQAGADSAITQYFFNTDSYFWFV
DEVQSRGVNIPIIPGIMPIASFSKLARFSETCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCDHLLQQGAPSLHFYTLNQAGLVSTICQRLGY
>A0A6V8MZ44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomonas paludis|TrEMBL
MKIIDKMNRNGQFISLEFFPPKDKNEWPGFFQVVDRLAQLKPLFASVTYGAGGSTRGDTL
EIVNRLKNEHGLDAMAHLTCIGAYRGDLQLFLDSLAEAGVNDVLALRGDLPKDVPPEFSA
CRTLLHASDLAAFIRESHPGMGIGVAGYPEVHPEAVDAEHDLRYLKLKLDQGGDFAITQL
FFDNALYFDFVAKARSIGIDKPIIPGIIPVVSLKVIQRIISLCGATLPAGYLAELEEADR
KGGAAAVQEVGVAHARRQAKELLAAGVPGVHIYTLNRDQAVLDLVQGLLP
>A0A2T6L9H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Promicromonospora sp. AC04|TrEMBL
MVAEVHPHRPTVSFELMPPRRPDVAPNFWETAQRLVAARPDFVSVTYGAAGGDRATSREV
LATLLRGTPVLPVAHLTCVGASREDVSEVIDEFLEAGVRSFLALRGDPPRDEPDWRPADD
DVRSSIDLVRLLRQVDERRCAADASTALRSAARPLTIAVATFPDGNPGARTTRDQEVRRL
LEKQEAGASFAITQFFYRAESYTGFVEAARSAGVTLPILAGILPTTEARRLRRVEALTGV
AAPAELLRDLDRLVAPDGAVDAEAQHARGIEYSATLAREVLDAGAPGVHVYTFNKHRPAL
DLLERVGLAGRAAA
>A0A7C3H998|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacterales bacterium|TrEMBL
MGSSSRVSRADEFRDLLSRRALVADGAMGTMLYTRGIFINRCFDELNLSAPQMVRDIHTE
YVRAGAEILETNTFGATRARLATYGLADKVADINCAGVRLAREAASERSHVFVAGAIGPL
GLHIEPLGPTSYEEARAMFREQIDALLEAGVDLLIFETFSSLSELREAVAAARDAAGNDI
PVIAQVTADEEGRLHDGADTETFARFLDELPADVIGLNCSVGPKPTLETLERMLAFTRKP
LSAMPNAGHPTRVEGRNIYLSSPEYMAQYARRMLWAGVKIVGGCCGTTPEHIKSIASEAR
SLQPGLRHAAAPASAPEAGKKALSKIPLSEKSPLGAKIASGKFVVFVEILPPRGIDASRE
IAGAKLCREAGIDAINVPDGPRASARMSAQVTCQLIERGAGIETVLHFCCRDRNILGIQS
ELLGAYAAGIRNLICITGDPPRMGAYPNATAVFDVDSIGLCNIVNNLNQGLDIGGHPFGS
QTGLVLGVGANPGALNLEEEIRRTEWKVLAGAEFIVTQPVFDISLLEQFLDKIRGFRIPV
IAGIWPLTSLRNAEFMVNELRVPVPEEFMERMRAAKDPEQARREGVAIAQEMVRRVRPMV
EGVQLSAPFGRYELAVEVARAVGPR
>A0A443L4W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKHIKKILALRGDISDEPMKDDFRFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPEKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFSV
>A0A4R5PBA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides franklinii|TrEMBL
MTTHPLDRDGPVAELQDPGSIADRLAAVQPGEVPFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYATELVQLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVIATDPEQGAKPIIPGLMPITSLRSV
RRQVELSSSTLPAALEERLLRAAGDGPDEDRDEVRKVGVEVTTAMAARLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A401QZE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albulus|TrEMBL
MRDLLASGKRSFSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTAELRNIIGQYADAGIRNMLALRGDPPGDPMGDWIRHP
EGIGYAAELVQLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVDKCRAGADFAITQMFF
YPEDYFRLRDRVHAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAARILAVKDDP
AAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQRP
>A0A640S5R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces caniferus|TrEMBL
MNTLRETLAAGERSLSFEFFPPKSAAGERTLWQAVRRIEALSPTFVSVTYGAGGSSRDRT
IEVTKRLARDTTLRPVAHLTAVGHSVAQLRHIIGQYADAGVRDVLALRGDPPGAPRGPWR
PHPHGLRHAHELVTLVKEAGDFSVGVAAFPERHPASPDWDSDIRHFVAKCRAGADYALTQ
MFFRVEDYLRLRDRVAAAGCDTPVIPEIMPATDVRQIRRFAELSGAAFPEDLAHRLEAAR
DDPAAAHRIGVEHATLMAERLLAEGAPGLHYITLNRSTATLEIHQNLGLSAAVARRQPDR
H
>A0A4Y8Q0G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. MEC084|TrEMBL
MSQAPHLPPPVSFEITPARRTEDAPEVERAASALAAAAPSFISVRTGAAGVCQERSLALL
RHVRDTAGARPVGHITGGGLARAELTERIEAHLAAGVRDFLAVRGDAPRAVRARPGIETP
AAIRLLRRIAAAQGLEVAVGVAAHPHGKAGVTDSHGDVAALLAKQAAGAAFALTQVVFDA
ASYACYVARARRAGVTIPVIPGIMPIASPARLRRITALTGVQAPVAQVLELENEQDPRRW
EEIAVARAVRLGRDLLDAGAPALHVYSLNRPETALAVAAGLRGETDAAIREAAIRDPRGA
LVA
>S9VU38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691)|TrEMBL
MKIVDLIHGLPKGSTFYSFEYFPPKTTVGLENLMSRITRMSNNMLPLFSSVTWGTAGSTA
SVSVLLAKLLENQHRVPACLHLTCTNVDRKVIDETLETAKNAGIRNILALRGDPPLNSDH
WEGKLSEFEHAVDLVRYIRQKYGDYFCIGVAAYPEGHADSNVPELTRDPARDMPFLIEKV
KAGADFIMTQIFYEPNAFIEFEKTLRNHESGVFQDIMIIPAVMPIQSFSILKRMTRLCGC
SIPESLMKRIEAVKSDDEAVKSIGVEHAVEMIQTIMRNTNHRILGFHFCTLNLEKSVARI
LKHSSLLTRRWEQYESQLQDENLRKTTIRRLSLNETPELHNHVVIPPDDSLKGISSSLRT
QTNEASLATHRDSLTTDAPFSVSEGSGVLGRQANWDDFPNGRFGDPRSPAYGEIDGYGPT
LHFPQQEALRLWGYPVDESDITSLFQKHIKNDIHAIPWIDEPVDDETKLISQYLLKVNGR
TWWTVGSQPTVNGAPSTDPVFGWGPKGGKVYQKAFIEFFISSKDFNNFVKKWHDNDQITY
YAGNNKGDFLTNAPNDGASAVTWGVYPGREIIQSTIIAEVSFKAWMNEAFDVWAEWAYLY
PKNTATRNLLEHCTDDRWLVSIIHHDYMDNDGLWKALEVVM
>A0A117UY54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium fuchskuhlense|TrEMBL
MAAALIHPNWDKPPLGVTDGFSLEMTAKDEGSLREAAPLIPVDTPIAVTFLPGEDVAARV
KATVAVRELGFEPMPHFSARRITSEDDFEGYLKAVVEQAGVQRAFIVAGDPPEPVGPYFD
TSALIATGAFERSGIKAIGIGGHPDGHPNMTEQQCWDVLVKKVAEIEARGMAPLIVTQFG
FDPDAFLAWLLKLRALGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTAVLRKYGISVTN
LLGNAGPDKLVDAFAKGLGPQHGRVRLHFYPFGGMVKTLEWIHAYNAKHGIPA
>A0A562ZPM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenimonas sp. HX-9-20|TrEMBL
MKLPISLEFFPTKTDEGAQKLRVARQKLYALKPEFCSVTFGAGGSTQDGTLAAVTEIMGE
GCQAAPHLSCVGQSRESIRDRLAAYGAAGIKRIVALRGDLPSGYGLGGEFRYASDLVAFV
RAETGRQFHIEVAAYPETHPQAKSPGSDLEAFAAKVEAGADSGITQYFFNPDAYFRYVDD
LTARGVRVPVVPGVMPITSSTQLIRFSDACGAEIPRWIRMRLQSFGDDSESIKAFGLDVV
TALCERLVAGGAPGIHFYTMNQANATLEICERLS
>A0A1Y0I5N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleiphilus messinensis|TrEMBL
MRENPPDILYGIIFSTTADKQDDCVRRTRSQMNSQNQIQRRFSFEFFPPKTPAGMEKLQT
VRDELATKCPDFFSVTYGAGGSTQERTIDTVLKLHNQGIDTAPHLSCIGATRNDLTELLN
LYKENNINRIVALRGDLPSGMGAHGELRYANELVEFIREHSGDHFSIEVAAYPEFHPQAT
NAEADLINFKKKVDAGANSAITQYFYNIDAYFYFIDRVEAMGIDIPIVPGIMPITNYANL
VRFSDMCGAEIPRWIRKQLEAYGDDVESICKFGEEVVSEMCSTLLQEGVPGIHFYTLNQA
APSLKIWENLNLDALVSKA
>A0A1J7JFV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coniochaeta ligniaria NRRL 30616|TrEMBL
MHIREMLADAERTGEPSFSFEYFPPKTAQGVQNLYERIERMYNFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYFGLETCMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPPREKEK
WVATEGGFQYARDLVRHIRDTYGDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGATF
IVTQMFYDVDNFLRWVDKVRAKGITVPIVPGIMPIATYASFIRRANHMKCKIPEDWMTKL
NPVKNDDVAVREVGKVLVAEMCRKILAAGIRHLHFYTMNLAQATRMLLEELDWMPSVNRP
LKQALPWKQSLGLGRREEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEENRKKWGEPRSISDIAAMFVKYLEKKIEALPWSESPLTSEADSIKEDLIA
LNKRGFLTINSQPAVNGVKSSHPIHGWGPPNGYVYQKAYIELMVHPDVFPEMVRRIEQNP
DLTYYAVKREGNFTTNAPNEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGTDW
ARCYDANTPSRLLLEDMMEHWYLVNIVNNDFHEPRTIFEVLDGLAVPNLDAVPQPEAKAN
GVHHTETTTTAEAPSSA
>A0A6F8TZ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas hydrothermalis|TrEMBL
MSSQEHPLGISFEFFPPSTDAGREKLMHVRDELAARQPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
HFVEKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GTDVVSRLCERLLDGGAPGLHFYTLNQAAPVLKIVDNLRG
>A0A485DVR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia enterocolitica|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDIGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A1V4VT43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelotomaculum sp. PtaB.Bin013|TrEMBL
MDAANITDCQTAVVRMSSIGAGVHILREGIEPVVQMTCRDRNRIAIQSDLLGAYSLGIRN
LLCLSGDHQMFGNHPTAKNVYDVDSIQLIRLVRRMKDEKLFFSGEAFNGQEPRFFVGAVA
NPFADPFEYRVDRLEKKINAGAEFIQTQTIYDLERFTRFMEMCVARGLHERAYILAGVTP
LKSWRAARFLQTSVPGMIVPDDIVRRLKNAENQQEEGKNICLEQIKYIKEEVKGVSGFHI
IAISWPEVVPDIVKSSGLYPRPVID
>A0A380XQ60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus firmus|TrEMBL
MSFLNKLKNEIIIADGAMGTLLYSYGTDSCFEELNLLQSEQIQHIHEAYIGAGAELIQTN
TYAANYLKLQRYGLEDSVKEINSAAARIAKKAAAERAYVAGTIGGIRGFKPNMITLEEIK
RSFREQLYCLLLENVDGILLETYYDLEELETVLAIARKETDLPIIAQVSLQEAGVLQNQT
SIADALAKLEGIGADVVGINCRLGPHHMLKTLESVPLPKHAHLSAYPNASIPAYTDGKFH
YEGDAEYFRQSAIEFRNQGVRLLGGCCGTTPDHIKAFADVLKGLPPIEEKEIKAVNKVIV
SEKPESSRELPPLQDIVRERPSVIVELDPPRKLDTSRFFEGAKALKEAGIDSITLADNSL
ASPRVCNSALGYLVRQQTGLRPLVHVTCRDRNIIGLQSHLMGLHALGLNDILAVTGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSFSGKDLGQKAAFSVAGAFNPNVRSLEKAVG
RLEKKIEHGADYFISQPVFSEEKLLEVHEAVKDLKAPVYIGLMPLTGSRNAEFLHNEVPG
IKISDSIRSRMASLKDDPAQAGTEGIAIAKSLIDAAAELFNGIYLITPFMRYEMTVELSN
YARETTERLSRRKQHA
>A0A239CHS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noviherbaspirillum humi|TrEMBL
MTRNTYSFEFFPPKTPEGAEKLRAARARLVALNPQYFSVTFGAGGSTQQGTLETVLEIQR
EGHEAAPHLSCMGSSPDTIRTLLNEYKSQGIRRVVALRGDLPSGYGGFGTTGDAFRYANE
LVEFIRKETGDWFHIEVAAYPEVHPQAKSPQDDLASFARKVKAGADGAITQYFYNADAYF
RFVDEAKKQGVEVPIVAGIMPITNYTQLVRFSDMCGAEIPRWIKLKLASYGDDTDSIRAF
GLDVVTQLCERLLQGGAPSLHFYTLNQANATLEICRRLNGTAL
>F0RD99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulophaga lytica (strain ATCC 23178 / DSM 7489 / JCM 8516 / NBRC 14961 / NCIMB 1423 / VKM B-1433 / Cy l20)|TrEMBL
MKVTDHIKNANGKTLFSFEIIPPVKGRNIQELYGNIDPLMEFKPPFIDVTTSREEYIYID
RDGLLDKKLTRMRPGTVGICASIKHKYDVDTVPHVLCGGFTREETEYLLVDCHYLGIDNV
MALRGDAMREQKYFEPTKGGHKYAVSLVEQIQKLNCGTYLHEVIETDNCSDFCIGVAGYP
EKHMEAPSLLTDLKRLKQKVDAGADYVVTQMFFDNSKYFEFVKAAKDFGIHVPIIPGIKP
IAVKKHLQLLPQVFKIDVPQDLVDAVEDCKDNKAVRQVGVDWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAKELF
>A0A2J8KXB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pan troglodytes|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKAHPECERDGGSMTLRP
DALRWSHSCPAFLLHSAASLGNPTLLRVSPTPASTPPPDDGS
>A0A2E5FAI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cycloclasticus sp|TrEMBL
MATDLNQPISFEFFPPKSEEGREKLLAVSQQLGQLEPAYFSVTFGAGGSTQQGTIDTVLD
IKNQGFSAAPHLSCVGSTKDNIRKILANYKKHGIDQIVALRGDIPSGTLDIGEFRYANEL
VEFIRKETGDHFHIEVGAYPEVHPQAANAQSDLLNFKRKVEAGADSAITQYFFNVDAYAR
FVEDCKKLGLTIPIVPGIMPITNYAQLARFSDMCGAEIPRWIRKRLEGFADDRESIKAFG
IDVVSELCQSLLEGGAPGLHFYSMNQAEASLTICRHLGFNKG
>A0A5C8UUB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacisediminihabitans profunda|TrEMBL
MTTTEAHGLERVPFSFELFPPRSDAAEHNLWHTIQQLAAVGPDFISVTYGANGSSRQSSL
HVLRYILENTSVSPLAHLTCVGSSHFEANRLVREFLDAGVTSFLALRGDPPRGAVEGDHF
LGDLGSASELVQLIHRVQTERAQYATLRSRSAGGVGQIPTSRAKVRVAVAAFPNGHPRSV
RSNQDIDTLLAKQVSGATMAITQLFFHADDYLRFVADAMAAGVTIPILPGIMPATNPVRL
SRILELTGERRPESLARRLESTDSVEEQHAIGVEHAIGLATEVLDGGAPGLHLYPFNQHQ
AVLSVLEGVGLTTATPSTARANIKESA
>A0A0F2PTP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium BRH_c4b|TrEMBL
MDLKSKLGQEFVFTTELGGINGTLIEESLAKARDYAGIDAINIHDCPNARLRMNSVMAAA
ILQKELGITAIPHFTCRDRSLLGTQADLLGASAMGIRYFLVTTGDGPQHGPYQSSAVYDY
NTLKLIEIIKGFNQGRDANGEAFKGQTDFAVSATATPGAKNLEAELKRMSGKKTAGADFF
QTQAVYDVAQAKAFLALARTLGKPILLGLMLLKSLKMAEFVNKNVTGITVPERIMKELEQ
GKTGFDIACEFIREIYQEVDGLHIFGMGNVALTNKLVEFTRSLL
>A0A538TWQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium|TrEMBL
MPAALLLDRLARAPLLADGAMGTMLYQSGIGFDQCFDELNLSRPTLVESIHRDYLAAGAE
LIETNTFGANAVRLTAHGLEERVRVFARQGAKLARQAREIVGVNAFVAGSLGPLGKPLEP
FGHITVRQAEEWFQATAEGLLEGGCDCFILETFQDLTEILAALRAVRRVSLELPVIAQMT
YGEDGKTLYGHAPTLAVKALRHAGASVVGLNCGMGPQATLEVLEEIVRAAEDTPVSVMPN
AGLPQMIEGRFLYLASPEYFADFAARAVEVGARIVGGCCGTTPAHVRAMRERLVSRLPAE
KLAPGAEVRVLEPPPAPIAPPVSAGEPSILAVLREKFVVSVEIDPPRGITTQKVMEAAAR
MAQRGVDCVNIADSPLARIRMSAVALAYLIRTHFPRLEVILHYTTRDRNLMGLQSDLLGA
HALGIRNVLCLTGDPPSLGDYPNATAVYDTDAPGLMRIVHRMNQGVDLAGSSIGAATRFA
IGCGVNPTAEDLDKELDYVKRKLDAGPHFVMTQPVYELASWQRFVERLSALTTIPILIGI
LPLQSYRHAEFLHNEVPGIHVPAHVRARMREAGNEGQRVGVDLARELLARCRAQANGVYL
MPSFGRYENCLEVLEGP
>A8ERC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter butzleri (strain RM4018)|TrEMBL
MFKTLIQKLQEDKYLTLETTPQHEPSMHNIIEKIKKFNLQDKIDGFSCTDNPLAKLRYNS
LFAALKLQQEFEKPVIATMTMRDRNKIALQSDLLGANDFDVRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGHPFKIEPKQIFPFAVVNSYAKNFSSLEKKLHLKI
QNGAIGIITQPIFDIENAQKLLESFDIAKENVEGDKRKSQLIFGIFPVTKLRTALFLSAQ
VPGIHVPQFWIDALEKAHSIGEEEEYKVGMELSSNLFKELNKLHPKIHLMTANRFDVANE
IIS
>A0A840C372|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chelatococcus caeni|TrEMBL
MSHAPFRPSRRGACPVRVSFEFFPPKTPEMEATLWASIERLAPLGPHFVSVTYGAGGSTR
ERTHSTVKRLVEETPLAPAAHLTCVSATRAEVDEVVRAYWAAGVRHIVALRGDPAEGIGA
AYTPHPGGYDGSPELVAGIRAVADFEVSVSAYPEKHPESVSIDADIELLKRKVDAGATRA
ITQFFFDNDVYFRYLDKVRARGIDIPIVPGILPVQNFKQAANFAARAGASIPAWLAGRFD
GLDQDVETRRLIAAAVAAEQVIDLVDRGVTDLHFYTMNRADLVYAICHLLGLRAGTAVAE
PVAAAAVA
>A0A4Q9Y3W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus paraplantarum|TrEMBL
MKLKQALQQRILVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIQAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAVTAREHADHPVYILGTIGGLAGDTDATIQQ
ATPATIAASVTEQLTALLATEQLDGILLETYYDLPELLAALKIVKAHTELPVITNVSMLA
AGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPTNVKLAVYPNAGLP
GTDQNGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSSRSIVAHNQ
PTAKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTMIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TAVSTKSISRKLSYGCDYIITQPVYDLANVDALADTLAANHVDVPVFIGVMPLVSRRNAE
FLHHEVHGIRIPQAILDRMAQAERTGHERATGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVNYVQAKNLIKVQ
>A0A1W9XN42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioclava electrotropha|TrEMBL
MTTPKVSFEFFPPKTLDASFRLWETAQVLAPLKPEFTSVTYGAGGTTRKLTHEAVGTIHK
NYGLNVAAHLTCVEATKAETMEIVDAYAEVGVTEIVALRGDPPQGAKHFTPHPEGFASSV
ELIEALAEDGRFTIRAGAYPEPHPDAADNMADVRWLKRKVEAGATSAITQFFFEPETFFR
FRDACEREGIDAKIIPGILPIQSWNGAKKFAQSCGTSIPAWVEEAFEAAIRDGREHLLAT
ALCTELCDKLIEGGVEDLHFYTLNRPGLTRDVCHALGVTPDTVLEKVA
>A0A2V4XIZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella epiphytica|TrEMBL
MKVTEHIIKANGKTQFSFEILPPLKGQHIQSIFDNIDPLMEFKPPFIDVTYHREEYVFKE
MENGLLKKQVVKKRPGTVGICAAIQNKYAVDAIPHILCGGFSKEDTENFLIDLDFLGIDN
VMALRGDAVKSETYFKPEKDGHAYANELVSQIENLNKGKYLDEELLNSSTTNFCIGVAAY
PEKHMEAPSLDSDIHFLKKKIKNGASYVVTQMFFDNQKYFDFLSKCRAEGITVPIIPGLK
PIATRKQLNLIPHRFHVDLPEDLIIAIVKCKDNKAVKQVGIEWCIEQSKELQKAGIPILH
YYSMGRSDNIRTIASKLF
>A0A1V5JHL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium ADurb.BinA028|TrEMBL
MAVLPRAAHLVRSIPDALAQGRPSISFEFFPPKDDAGEAALWEAIRDLEKTRPTFVSVTY
GAGGSGRDRTIRMTDRIAQETTLTPMAHLTCVGHSVAELRSIIGHYVNVGVRNVLALRGD
PQGGLDQTWERHPDGLDHADELVSLLRTLGPFTVGVAAFPDRHPESPSLDHDADVLVRKA
DAGADFAITQFFFTREAYVDLRDRVVARGRDLPIIPGLMPVTNVRQLARMTQLSGQPVPR
EVTERLERVADDPVAVRAVGVEIATELAQGLLDEGAPGIHFITMNRSTATLQVWGNLGLE
AAQ
>A0A1H6Y728|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. AP50|TrEMBL
MTLNDPAAPLYADLAGDCQVSFEFFPPKTEKMEAQLWSAIETLTPLAPKFVSVTYGAGGS
TRERTHNTVARIAKETPLAAAAHLTCVAASKAEIGEIADAYWEAGVRHIVALRGDPPEVG
GTFEPHPDGYTGAADLVEGLMQRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFAPDTYFRFMDKVLAAGISADIVPGIMPVGNFAATQRMAAMCNTDVPQWMARLF
EGLDDHPSARQLVSATIAAELCRKLYEGGVRDFHFYTLNRAEHSYAICHLLGLRPKVMAD
AAA
>A0A414RW98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM23-17|TrEMBL
MRVDEVFKQAASQGTTSVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>T0JKA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. UNSWDHB|TrEMBL
MENTFRKAIQDNNEFIVTWELVPGRGSKEVSQEKALQLAEQAAKGKKVHAVSLTDNPGGS
VGINPEGIGREIKSLGIDAIIHVACKDKNRTQLESQLFSLERSGLHNLLILTGDYDPGNF
FGRPKPVFDLDSTQLLAFITKMNGGLELPTVRGIHKLQPTHLFAGAAVSPFKATEAEQML
QYTKLKKKIENGAKFIIPQVGYDVRKYHELYQFVKHNNLPGCLMGNIYLLTYGAAKAMSM
NKVPGCIVTDKLVAELEQEKQSSDKGVAAMLDRAAKLFAILKGMGYKGVHLGGHNTTYEQ
VEYIIDRGNELTANWQDYIREFDYPQKNGFYVYAKDEKTGLNTDQKSNDYNNYEKSFDLN
YKMSRVVHKMMFEPNKGMFGFMRGFCHAIKDSALEKPFHGIEHLAKSCMYNCQDCGDCAL
IDVAYVCPMGNCPKNQRNGPCEGSYNGWCEVYPDKQKCIWVKAYYRLKDYSEEEKLNSYH
VSPYNWEKQHTSGWINFFEGQDHSAERLGIRPRTKSKEKE
>A0A8E5JJJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Enteritidis str. 607307-2|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A105T2V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. TAD18|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVNVPAAPHLSCVGDSKDDLRSLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGSHFHIEVAAYPEMHPQARNFEDDITNFVRKAHAGADSAITQYFFNADSYFR
FVERVQEAGVTIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVISDMCARLLDGGAPGLHFYTLNQSEPSLAIWNNLNLPR
>F6RK00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciona intestinalis|TrEMBL
MSPVTNGINGHDFTVESLADKILSRVESNDPFFSLEFFPPRTEQGAANLIGRFDRMRAGG
PLFVDITWHPAGDPGSDKITSSTKIAGTVLNYCGLDTMLHMTCVKQTKETIKKNLEKTKN
LGIRNILALRGGISPNADADESWGYQEGGFNYGVDLVRFIKQEYGDAFSICVAGYPNGHP
DSTSYQDDLLHLKEKIDAGGQFIITQLFFTAEEFLTFVKDCREIGIDCPIIPGIFPIQTN
RSLVQLTKLSKLSIPEEIQKVIEPIKDNDAAIRKYGIDLATDMCRTLLNSGKVHGLHMYT
LNLETATIQILKNLGLWCQDVAKPLPWKTSANPERRENETVRPIFWCDRPKSYIHRTQGW
DEFPNGRWGDSASPAFGELKDYHLFFLRSRTAKDKLRSLWGKELTSEADVWKVFKHFITG
AVNENGVKVTETPWNDDGLSPETNVLSSTLSRYNELGVLTINSQPNVNAVPSTHPIYGWG
DKGGYISQKAYLEFFINKHYAEALKTVLPKYHPRVNYHMINKCGTTDHTNADRSNPNAVT
WGIFAGKEIIQPTVVDPVSFIVWKDEAFGLWHERWASLYEKGSKSREIINDIADNYYLVN
LVDNDYPADSILWEVLDEMLAASQKVDMGKKSNGVCGENGTQKIEELQIH
>A0A161XWF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Secundilactobacillus collinoides|TrEMBL
MKVVNCFEHRPVISFEIFPPRAKASEKATNRFYASLDTLASLEPAYISVTYGAGGSNDHA
STLALCRYIKVHYGIGAVAHIPAVAFNAQSLKTYLADLKQAHVENVLALRGDLPADGRPN
NDFPFASDLVAAIKRESDLNILGACYPDVHPEAENCVVDVQHLKEKVDAGASQLISQLFF
ENEHYFSFLERCELAGIKVPIQAGIMSVINERQIAKMATIGGVELPPKFLKMMHHYQDNK
IAMRDAGIAYAVDQIVDLLSEGVDGIHLYTMDNPVVTQRICSAIKTLI
>A0A0R1U491|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus pantheris DSM 15945 = JCM 12539 = NBRC 106106|TrEMBL
MKTSQLFTRDQPVFSFEVFPPRDLTAPNATQKVCDTLEVLQRVQPDFVSVTFRNAGLAAK
DSTIAIATLIRDKYGIEPVVHLPAAKLSRGDVDGLLNDLQNAGIQNILALRGDIPATGRT
SNDFPFASDLVSYIHTRGDFNVIGACYPEGHPESADSLADIQNLKRKVDAGTSELITQLF
YDNQEFYHFQERCRFAGITVPIEAGIMPLMTAKQAAHMMAGVTIPEKLQALINRFADKPE
ALRDAGIAYAIDQIVDLLAHGVDGIHLYTMDNPEVAARIIEATRNIVRA
>A0A1F4N2N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldithrix sp. RBG_13_44_9|TrEMBL
MHVIEAIKSSKKIFISLEITPPNKGQSIEDLYRVIDPLIEFNPGFISVTYHQPQVVYEER
DRVIYRVPKRKKPGTVGICAAVTNRYKIDTVPHFILGGFSKFETEDALIDLHFLGIENIF
AVRGDPAPGEKSFIPEQGGHRFASELVEQISNMNRGIYLEDLENAQPTNFCIGVAGYPEK
HYEAPNFDKDLQYLKQKVDQGAHYIITQMFFDFQVYKNFVERGRSIGIKVPILPGIKPII
SLNQLSSLPRDFHISIPSKLVESMENAKSSTEARKIGINYVKDLCQQLIDFGVPGIHIYT
MGKGTATQELLTCLFK
>A0A149RZ75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter oxydans|TrEMBL
MADHPSLCHSDMLVPVLSFEVVPPRTDAMEQRLWQCMRRLAPLSPRFVSVTYGAGGTMQA
QTQATVLRLKQETTLVPAAHLTCIGATREEIDDIARTYWQAGVRHILALRGDAPAGTDYT
PHPGGYAYAGDLVAGLRRIADLEISVAAYPETHPTAPSPQADIDNLKRKFDAGASRAITQ
YFFEASTCLRFLDRCLAAGITAPIVPGIMPVSNYDQIARFSAFCGVTVPVWLTHLFEGTA
KNPELCRIAACIVAAEQVRTLQSHGINEFHFSTLNRPDLTCAIAHLLGVRPASETDS
>A0A5E5QDF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Gammaproteobacteria bacterium|TrEMBL
MPYKYAIISVFLPAFRMPMKTSFEFFPPRTEKGKQTLHQVRQELSSLNPEYFSVTFGALG
TTQEVTLETVLDIQKNDTVAAAPHLSCIGSKKEIIIELLDQYKAANINRLVALRGDIPSG
VRDIGDFHYANELVEFVKSQYNHHFHIEIAAYPEMHPESKNRLTDLQHFADKVKAGADGA
ITQYFYDADAYFKFVDATEKLGINIPITPGIMPITNYTQLVRFSKMCGAKIPHWILKKLE
LYQDDFDSLSAFGLEVVTNLCQTLKAQGVNNFHFYSMNRSQPSLEIAKHL
>A0A4R3ZMB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter oxydans|TrEMBL
MEQRLWQCMRRLAPLSPRFVSVTYGACGTMQAQTQATVLRLKQETTLVPAAHLTCIGATR
EEIDDIARTYWQAGVRHILALRGDAPAGTDYTPHPGGYAYAGDLVAGLRRIADFEISVAA
YPETHPTAPNPQADIDNLKRKFDAGASRAITQYFFEASTCLRFLDRCLAAGITAPIVPGI
MPVSNYDQIARFSAFCGVTVPVWLTHLFEGTAKNPELCRIAACIVAAEQVRTLQSHGINE
FHFSTLNRPDLTCAIAHLLGVRPASETDS
>A0A5B0QTX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia graminis f. sp. tritici|TrEMBL
MAKKVVQLIESLKDDQVYFTFEYFPPKTIDGLSNLYARIQRMANLKPSCAHVTWGASGST
SDTSLEIAAMVQDQLAIPACLHLTCTNIQRTHLDQTLAQAKESGIVNILALRGDPPRGTE
HWIPTDHEFQHAIDLVKYIRKEHQDHFCIGVAAYPEGTTEFDQDQELNYLKQKVDAGADF
IVTQLFYDVDIFLNWVKACRNLGINVPIIPGIMPIQSYDGFRRLTALCKTNIPESIHSKL
IPIKGDDQAVRDYGVELSTQMIKRLQVNGFKSFHLCTLNLERSITRLVNQLGWSPGGIKH
CQPLLGPSVKIGTAEIVQGGLSVGWDEFPNGRFGDQRSPAFGLREGYSSSLTSAFSHLTT
DVHALWGTPTSLKDITQIFCAFTQGKLPSTPWSEEPLALETSSITPFLLKLNQNGWWTVG
SQPAIDGADSLDSVVGFGPQGGRVYQKSFVEFFVPHAHLEGLLSAVDDYNKEHSDGVAQL
RYYAGNCNQDQIRSNMAPGETNAVTWGVFRGAEVVTTTLIEAQSFKTWKKQAFEIWNDWA
ESFEPNSANQRLLNQIEDSYWLCSLIDHDFKQPEHLWSFLIAHQQRLLSHQSS
>A0A177AKU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus destructans|TrEMBL
MADSPTTDKITDKIAALPQDASYFSLEFFPPKTAMGSTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSKALVDDALKAAKEAGIQNILALRGD
EPRGEYKDALEEGKEGEEEFVWAIDLVKYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
EHDLPYLVDKVQAGADFIMTQLFYDVDAYDNFEKVLRGHSSGAFKTIPIIPGLMPIQSYQ
ILRRTTKLSNAKLPESIIDRLDAVRTDDEMVKKVGVDILAEIVESVKATKQRTKGPKGFH
FYTLNLEKAVAFILERANLIPSFTPVLTSDAFAVDDITDTIPLPQLLINGEKKSRRQSSV
GSGPHNFVIIDREEASGFETTGAEAAVPKNGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRPDITSIFVQYINGTLSALPWSDE
PITAETNLIKDELVKLNQKGWWTIASQPAVNGAHSQDEVVGWGPKGGWVFQKAFVELFVP
TPDWARLKPLLEGNGEVSFLAQSASGEFLKSKLDLGPGEEGTETNAVTWGVFPGKEIVSP
TIVEEVSFRAWAEEAWQMWGEWAAVFGNSGEESRRFLGGVAKDGWLVNVIWHDFVGMCKA
KKGRSEEEGYKGLWDVLIEA
>A0A4V6LF79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus australis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFHYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATNALFNHQSLG
>A0A317RAT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melaminivora alkalimesophila|TrEMBL
MNARTPQAAAPRLPVSFEFFPPKTAEGVDRLRTVRAQLYQRRPQFCSVTYGAGGSTQEGT
FAAVREILAEGMDAASHFSCIGATRDSVRAQLAELKAMGVRRLVALRGDLPSGYGVGGEF
HYASDLVAFIRAETGRDFHIEVAAYPEIHPQARSAEADLQAFATKVRAGADSAITQYFFN
ADAYQRFVDDVRRMGLDVPVVPGIMPILGATQLMRFSDACGAEIPRWIRLRLQGFGDDTA
SIRAFGLDVVTRLCEQLVQAGAPGLHFYTMNQSAATLALCERLGL
>A0A178I4T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia elaeis|TrEMBL
MLDDNLRASRLTAGQRPDLQLSFEFFPPKTDAMEERFWESIQKLAPLHPRFVSVTYGAGG
STRERTLRMVSRIKSDTGVPAAAHLTCVGATRDEVDEVVRGYQAAGVSRIVALRGDPPEG
VGQPFTPHPEGYQNAADLVAGIRRIGDFDISVAAYPEKHPQSADWDADIDNLKRKLDAGA
DRAITQMFFSNADYLRYLERARRAGVTAPIVPGIQPIHSFKQISGFAARCGASIPAWLAE
RFEGLEDDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRP
>A0A1Y3F138|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella nativa|TrEMBL
MASLEAVELKATRHDLNSAAKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTTEGLI
NLLKRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCILNFCLLDTMLHITSVQYD
EKTVLFNLERAKKIGIRNILALRGDISDDANVTTTDFQYACQLVRFIRSHYGDYFTICVA
GLYLLYAKVDAGADFIITQLFFNEMHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMKIV
QLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRNLLNREHHVVPGLHFYTLNQEK
SILEQIGFWKKAPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYLCRTRDWKQFPHSRW
GDVGNPAFGNLKHYLFSCIDQMDDSCALDMWDKELSTLEHVRDIFCNFIARTPNRHGHSV
RRLPWNENHLDPAADVLKNELIYYNSNGILTINCQAAVNGLPSSDPIFGWGEANGYIYQK
GYLEFFASSTCTTILLNHVQNFPSINYHAINFDGSFETFNYDEDATVALTWGVFVGQEIV
QPTVANAASFRVWKDEAFDLWQRWAGLYESGSIGRKLLQRIHDDYRLITLIDNDYPQPCS
FLGETATPSATKSTDVSSCFFPHDTLSRSEQCEHLRTSWLCCLLAAGVVVSAGVAPALFL
PEQVDNSVGWAGCLSLNRLLSFAVGSLIGDVFLHLLPDIWRSTDAEGVATAGWWTVMGLF
FCFSVEKCAVKQDDQRSKRLVAAGLNLLANLVDNFCHGLAIGAGFLVSVRLGVLTTFAIL
VHEIPHEIGDFALLLRANVGRRRAVGAQLATAAFGLAGALTALALNGGSTGVGSAWILPF
SAGGFLNVALVQVLPDLVRVDDAKESLWHVLLLLVGISAMASLNVLHF
>A0A6M1RWB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limisphaera ngatamarikiensis|TrEMBL
MEGTVLIRDVLARRASQGRPAVSFEFFPPKTPEGEQQFFKDVLPRLVQLGPDFCSVTYGA
GGSTREKTLTLVERIQKTHRLPSMAHLTCVGSSVAQLREIIEQARRRGILNILALRGDPP
RGETGFRPAPDGLTHAWQLVRLLREMGGFCIGVAGFPEGHPECREGKYADWDHLKAKIDA
GADFVITQLFFDNADYWEFRDYLHRAGVRVPLIPGVLPILGFQQVDRLTRLCGARVPEKL
RRRLEELAGDEEGSMAFGVEYATRQCEELLRGGAPGLHFYTLNRVHSTRQILENLGLARK
DSP
>A0A852A2M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calcarius ornatus|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRRVLQGRRGEVFDHMGAGGPLFIDVTWHPAGDPGSDKETS
SMIIAYTAVNYCGLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEE
VDGFNYAVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVYAGADFIITQ
LFFRPETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIK
DNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWNEDPRRPLP
WAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYL
KSKSPREELLKMWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLK
DQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVRALLKV
LRKYELRVNYHIVNVKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAF
ALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7C6MYB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterales bacterium|TrEMBL
MFIKDIFSSKTPVISFEVFPPKREFPLDTVYSTIEDLKDMNPDFISVTYGAGGSSKDRTV
EIASTIKNKYNIQSLAHLTCLTSSKAEIDLMLEQLKANNIYNVLALRGDIPIGGLQTYPQ
YKYAKDL
>A0A094KGC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus sp. KU2-6(11)|TrEMBL
MGLLDDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIEAGAEVIQTN
TYGANYVKLARYGLQDDVKEINEAAVELAKRAAKGRAYVLGTIGGLRSTNKSTISLEEVK
RTFREQLYVLLNEEVDGLLLETYYDFEELQTVLSIARKETTLPIIAHVTLHDIGVLQHGM
PLAEALRQLEQLGADVVGLNCHLGPYHMLRSLEEVPIPTHAFLSVYPNASLPQYRDGRFI
YETSEQYFEETARAFRDQGVRLIGGCCGTTPKHIAAIARALADRTPVCKKDVKQRHTIVV
QEAEQTKEPSLADIARTRRSIIVELDPPKKLGLTTFLEGAKALKEAHIDALTLADNSLAT
PRISNVAVGTIVKQQLNMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRI
EKKIECGAHYFLTQPLYSEKQIEDVYEATKHLPTPIYIGIMPLTSARNADFLHHEVPGIT
LSDDIRARMAACANDPVQSTKEGLAIAKALIDAAFDLFQGIYLITPFLRYDMTVELVRYI
HEKERLAKERTVYYG
>A0A8J7BFU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nodosilinea sp. FACHB-141|TrEMBL
MGYRLRTAAQADQFLVTAEVMPPKGGNPEHMLAMGQMLKGRVHAVNVTDGSRAVMRMSSW
AASLLLQQQGIEAVCQVACRDRNRIALQADLMGAHALGLRNILALTGDPVKAGDHPEARS
VFDLESVRLLKLLEKLNFGVDSNDKPLTDGALDLFAGAAIDPQSTSWSGLQRRFEAKVKA
GAQFFQSQLITDFDRLAKFMDQVASGYNRPVLAGIFLLKSAKNANFINRNVPGVNIPQAT
VDRLAAAADPLQEGVKIAAEQVQAAQQICQGVHLMAVRREDLIPQILDQGGVAPVDAALA
ER
>A0A7S7WDI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium sp. Rain0013|TrEMBL
MTAQSRTFSFEFFPPKTPEGIAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLATVLEI
RSEGHAAAPHLSCIGSTRENIGAILNEYRNNGIRHIVALRGDIPSGMVAAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLNNFVRKVHAGANSAMTQYFFNADAYFRF
VDEVQARGVNIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRQRMQAYYDDSASIRALGL
DVVTELCDRLLQHGAPGLHFYTLNQAGLVSTVWQRLGL
>A0A0V1LM70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella nativa|TrEMBL
MASLEAVELKATRHDLNSAAKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTTEGLI
NLLKRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCILNFCLLDTMLHITSVQYD
EKTVLFNLERAKKIGIRNILALRGDISDDANVTTTDFQYACQLVRFIRSHYGDYFTICVA
GFDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSKIVIPDSVLTTLESIKENAEAVRNFGI
SFAVQLCRKLLNREHHVVPGLHFYTLNQEKSILEQIGFWKKAPVRMFPWKKHTVHSVRCR
EAVRPIYWTARPKSYLCRTRDWKQFPHSRWGDVGNPAFGNLKHYLFSCIDQMDDSCALDM
WDKELSTLEHVRDIFCNFIARTPNRHGHSVRRLPWNENHLDPAADVLKNELIYYNSNGIL
TINCQAAVNGLPSSDPIFGWGEANGYIYQKGSFETFNYDEDATVALTWGVFVGQEIVQPT
VANAASFRVWKVVAQLSFIQFSLHTFGIFLFVFEQDEAFDLWQRWAGLYESGSIGRKLLQ
RIHDDYRLITLIDNDYPQPCSLSALLRAVISDYWGKKLDDG
>A0A315QXW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium sp|TrEMBL
MKIKNIFDEKEVVFSLEVFPPRPDVPIENIYQTLEELKDIDPDYISVTYGAGGGVRKNRT
CELSSIIKEKYDVEALAHLTCINSDQDTLNKILARLEAKDIENILALRGDKPVDGEPLGD
YDYSYQLIEHIKKHNDFGVAAACYPEGHLETESLDQDIEYLKQKVDYGVDYLISQMFFDN
SLFYKFRNKVEKKGIKVPIEAGIMPVINKKQVGRIIELSDAYFPQKFKKILDKYEDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKVD
>A0A4Q2KD93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Borkfalkia ceftriaxoniphila|TrEMBL
MILSKLFQNKKAVYSFEIFPPKPTAELSAVQNTIRELSALSPDYISVTCSAGGSNNAGTA
GIAKLVKECGVEPLAHVTCLHSDKAAVEAALAELSRNGVQNILALRGDRIEGRPLSPDFR
YASDLVSFIRAQGYAFDIAAACYPEGHPESENVREDIRNLKIKVDAGVSHLNTQLFFDNE
DFFRFMELCGVAGIDVPVQAGVMPLVKKNHVDRIVALSGGKIPAKISRMISRFYDKPEAL
MEAGIAYATEQIIDLLTSGAAGVHLYVMNNTYVARKITENIGYILGELNQQ
>A0A1Q8I2L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MRDNEPTAAAGSRGDALSSTETGSARRLPTVSLELFPPRPGKAASATWGRIDRLLATGPD
FVSVTYRPTFVTDPAGGDSGDEYEGNRCGIAPRVRAVQEQTNPSECVLAHVLESSTIPLM
AHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRADDVAGELRHADDLVRVIRE
VETDFFGDSRRHVTIAVAAYPATSDHIEAIEVLAAKQAAGADMAITQVFYDAADYVALTN
AASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSTLGSASGATLVERGIGATL
DLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDAVDRGYLQATP
GRGPSFLRCGSPGAALSSRHPVQPHTTITKENA
>A0A4S0R019|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.177.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDDMEARLWDTVTRLEPLKPQFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIREFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVA
GSAAA
>A0A2W6UWF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MLTPAAVRHADCPKTMTYGPCGGVNADGTCEVAPTPCVFLGDALPVRWDGDGTGGGAPSR
NTEAAAALVTGTGTGRPHPAVATTAGRDVLDILARRPLIMTGFPARAMVRDDIARTADEL
RGRADAVLSGDAAGSRTQYPPAYRAVLMTNAGMRAWMGINARDRNRVALEGELAALQDIG
VAGVHCVTGDHTRTGDRLDAQPVFDLEGTTLLPLARAQGLATSFAESPDAPPAALRGQRV
REKEQAGGMLCLTQYCGDAEHVASFIERGRQAGTVAPVLPGVPLVVDRAGAELLASFHAA
TLPTGYVHALFAARDVRREGIRLAIEYGRSLLAVPGVSGVVVAGGVQPGDEQAYARALAT
VAAELGGGSS
>A0A4V3MS08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.177.01.1.1|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPEAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLRGRQPWQREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A0E8XKX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia wautersii|TrEMBL
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIATDYWNSGIRHIVALRGD
LPPNSGKPEMYACDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFD
GLDDDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A1A9CBK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ncost-T6T-1|TrEMBL
MLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKATQE
IAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHPQGV
KYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFFRPE
DYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDPAAV
RSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A367RGK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc punctiforme NIES-2108|TrEMBL
MHHTHSHTAFRRAVQAGEFLITAEVAPPKGGDPAHMIQMAATLKGRVHAINVTDGSRAVL
RMSSLMASVILLQNGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALTGDPVKAGDH
PDAKAVFDLEAVRLLQLIRKMNQGVDCNEKPLTDGALDLFVGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFERLEKFMDTIAAGYKKPILAGIFLLKSAKNAQFINRCVPGVD
IPQHIIDRLAKAKDPFEEGIKIAAEQVQIARQLCQGVHMMAVKREDAIAPILDLAGIAPV
NQLVSM
>A0A4V3MW11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.177.01.1.1|TrEMBL
MPAGLSLRADAFINAFSLEVSAKAMPALRAEADRIPRGTVISIPYLASEDDDARLAAART
VRALGFEPMPHLSARRIGSAAALARFLERAVGEAGVARCLLIAGDLATPAGPFADSASII
QTGLLEHSGIKVVGIGGHPEGHPVMSSDERWQALERKCQDIEARGMAPLVVTQFAFDADT
VLAWLDGLRARGISVPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGISIGRLIGTA
GPEVFVDRLVRGLTSAHGQVSPHFFPFGGIAPSLEWMVQYRRRISGTGG
>A0A142M9J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter aminovorans|TrEMBL
MPEPKHRLSPENSPNLVAEGVSLELAPAQAAGFLPLETAFPEGSRVFLTHLEGKPLALQV
EAARQLRQAGFVPVPHFGARHFASPKEFVDLVGAHSRNGVTEALFVGGNPLAANGPLEDA
ADLLAHPVIADSTIRTAFIGGYPEGHPAIGRSALAHALLRKIAICHDRDLAPRIVSQFAF
DGAMMAAWTNDLHRAYPGIPVHLGVAGVTSLTKLIKFAMMCGVGPSLAALRRSGVGLFNV
LADKDPGDLVEAIETGLASNCGAQTFLHIFPFGGWEKSLSWLEEFRRRRAN
>A0A7X7VVS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistaceae bacterium|TrEMBL
MFIRELFRKNGPVISFEVFPPKADAPVEGVYRTIEALKDLSPGFISVTYGAGGSSRDRTV
EIASRIRNGYGIEALAHLTCRSHTAGEIDEICEELLDEGVQNILALRGDPQPSDAEDDRE
RSFFYACDLVRHLRRNHFGNFCIGAAAYPEGHIECQDLARDLDFLKMKVEAGAEFLITQL
FFDNELFYRFRDEASRKGIAVPIVAGIFPVLNAAQVQKIVSLCGVSLPPRFTRIIARYAN
SPAALAEAGVAYATDQIVDLLAAGVDGIHLYTMN
>A0A832IXQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacteraceae bacterium|TrEMBL
IALQSALLGANEYDIRAILALTGDPASMSDQPGTKGVFEGNSTLLLDIIKCFNGGIDYAG
KPLDERPGTIYPFAVSSAFAKNPRNLQKKLRQKLEHDAMAIITQPVYSTENAGMLLELFE
KAKVEVGSKAADAQLILGFFPITKLRTAQFLTSHVPGVDVPKEWHEALYEAKNSGDEAQE
KRGRELSGRLFEALYALHPRIHVMAANNFALAKEMISLVR
>A0A2K3JIX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon M9B2D|TrEMBL
MSYRSNLEKILSEGRFAVTAEIGPPKGADSNSIRDKVKLLRGSADAFNITDNQTAVVRLS
SLAGSVILLQMDVEPIMQITCRDRNRIGLQSDVLGAAALGVRNMLCLTGDHQSFGNHPTA
KGVFDVDSIQLLQIIKNMRDEGVFQSGDLLLSGRPPVFLGASANPYADPFEYQVDRLRKK
IDAGAEFIQTQSVYNVEKFSKWMDDVRSQGVDKRVHILAGVTPLKSIKMTERMKFHVPGT
DVPDVVYQRMKHSSDPAKEGYRIALETISELKNLPGIHGIHITALFWEEIIPALVKDAAL
ISRI
>A0A2R6I4H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QS_5_70_17|TrEMBL
MSLKRKKQEAEGVTDLLSEPRFELMPFESFGEQMQQLPDGAQIAITTSPTLGIEATLEWT
EKATAAGYEIVPHVAARYVRDEDHLREIARRLTEAGVDDIFVPGGDREEPAGEFESAYQL
LSTLDDLDYEFEEVGITGYPEGHEFLDDETLAEAMERKEPYATYIVTQLCYDPETVVDWI
EEIRGRGVDLPVEVGIPGVMKYQRLLEISQKVGVGDSVRFLRKTTGILGFVRQLVGSRGM
YTPDGLIEGLAPYAADPDYGIRGVHIYTFNQVPDTESWRLGALEE
>A0A8J7IWT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenihalocynthiibacter styelae|TrEMBL
MTRPNISFEFFPPKSLAASFRLWDTVQALAPLAPGFVSVTYGAGGTTRQLTHEAVTTIGK
STGLNVAAHLTCVDASRDETLEIAQTYAAAGVKEIVALRGDTPGAGVFEARPDGFGSSVE
LIEGLTQAGDFNIRVGAYPEAHPESTDMAQNIAWLKRKFEAGATSAITQFFFEPETFFRF
RDACQAAGIDGDRIIPGVLPIENWKGTRKFAERCGTSIPADIAQAYDNAARDDCHDLLAL
AQCSELCSDLLDGGVNDLHFYTLNTPDLTRDCCRALGIEPELKLEKVA
>A0A541BXU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elioraea sp. Yellowstone|TrEMBL
MNTASVLARWAAGPREGVPPISAQDLPAPQLSFEFFPPKTEALEQQLWACIRRLEPLAPR
FVSVTYGAGGSTRERTHATVTRLLAETTLTPAAHLTCVGASRAEVDAVARAYWEAGIRHI
VALRGDPPAGAAGYQPHPEGYAYAADLVAGLRRIGDFEISVAAYPETHPAAASPQADLDN
LKRKIDAGATRAITQYFFDTDVYLRFLDRCLAAGLTVPLVPGILPVTNFAQVVKFSAMCG
ASVPGWLARLFEGLDADPETRRMVAAVVAAEQVRRLQAAGVDEFHFYTLNRPDLVYAIAH
ILGVRPVQRG
>R7N8Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:76|TrEMBL
MKIRDIIDREQETLSMEVFPPKKDTDFEMVKEAALHIASLKPSFMSVTYGAGGSTKGNTI
KLASEIQKQYQVPAMAHLTCVCATKESINTALTEMKQAGIENILALRGDIPKDYDGEVFT
EFQHASQLVELIKKTGDFCVGGACYPEVHPDSKNKFDDINGLKEKVKAGCEFLTTQMFFD
NNIFFNFMYRVREAGIHIPIIPGIMPITKRAQVKNAVKLSGCNVPERFKNIIDKYGDTEN
AMKQAGVIYASDQIIDLLANGVKNIHIYSMNKPEIAKGIQDNLKGIIL
>A0A1Y2MRG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia autotrophica|TrEMBL
MPLGLPAVLRGPTMRGSHRKVVRVTTTSASTVTERISVDRPFFAVEFFPPKDDQGEADLW
RAIRRLEVLDPAYVSVTYGAGGSSRDRTVRTVERIATDTTLCSMAHLTAVSHSVDELRHV
IGSLAAAGVRNIMALRGDPPGDPLGEWISHPEGLEYADELVSLIKRSGPFCVGVAAFPYG
HPRSADLAADTDRLVGKFRAGAEFAVTQLFLEPDGFLRLRDRVAAAGFEQPILPGIMPLT
SEKTFHKGPELSGSPLPEALVERLSRYSGDAKAFRAAGMEVTGELCERLIAEGVSGIHFY
SLNRSTATTELIERLGLAEQRGTARGGRVPAQPATA
>A0A562WHQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sagamiensis|TrEMBL
MSAPPPLSPVDGPATPTGSPSAGPSLRHVLAGATRGLLLFGITPPRASATAEQAQEIARL
TRARLDPLDVDALVLYDIDDESDRNPDERPFPYLPTMDPAVFHAAHLAGWRRPAIVYRCV
GKYPEPELRDWLRAVDTGRVGSVFVGASSSSKQVRTTLPRAHALRRETRPDLAVGGVAIP
ERHTRDLDEHRRMLTKQERGCGFFVSQVIYDVDASKSMVSDYHYACRERGVTPRPVVFTL
SVCGSLRTLAFLQWLGVRVPRWLENALRHADDPLAESYEQCLATARELVTFCRRLGMPFG
FNVESVSNRKLEIDASVALAARVRDLLGRPSA
>A0A0H4WW70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcus hansupus|TrEMBL
MKIRNRLNPSDPCFSFEFFPPRTEEGEANLLKALEDLAALQPGFVSVTEGAGGSTRSKTV
ELVLRIKQETGIEAMAHLTCGGHRPDELRAVLEKLKDAKVDNILVLRGDPPKGQTHFEPQ
PGGFRYASEMTRFIREEDFNFCLGGACYPEGHVETPSRDDDLRHLKAKVDAGLDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQIQRFTRLCGATVPMRLALQLERVKD
QPEAMAQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRARS
>A0A1D9BE09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jeongeupia sp. USM3|TrEMBL
MTRPPISFEFFPSKTPEGVEKLRNTRRQLAQFKPEFFSVTFGAGGTTQDGTRNAVFEIQS
EGHQAAPHLSCIGSTRATIAELLQSYREHGIRRIVALRGDIPSGMVDVGEFRYANELVAF
IREQHGDWFHIEVAAYPEYHPQAQSAEADLRAFVGKVHAGADAAITQYFFNADAYFRFVD
EVQGRGVSIPIVPGIMPIQNFSQLSRFSDMCGAEIPRWLKLRLASFGDDSASIRAFGLDF
VTELSDRVLSQGAPGLHFYTLNAAGAVSTVCQRLGF
>A0A4P6B9M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorella sp. E306M|TrEMBL
MKTESKLEKILSQGHFVVSGEIGPPKHANPEGIKKHTALLKDYVDAMNLTDNQTAIVRLS
SIAAGVHVLQAGGEPIIQMTVRDRNRIALQSDLLGAYSLGMRNVLCLSGDHQSFGNHPTA
KNVHDVDSIQLIKIVKDLRDEKKFACGEELKGNEPRFFIGAAANPFADPFEFRVLRLEKK
INAGADFIQTQCIFDMERFERFMALVRERGLHKRAHIIAGVMPLKSAKAAKYMQQSVAGM
IVPDEIVNRMEKAADPRAEGVAICVEQIKHLKTIEGVAGVHIMAVMWEEIIPTIVKEAGL
YPRPKVE
>A0A6C0U158|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineobactrum salinum|TrEMBL
MTRISFEYFPPKSDAARATLLETTTPGLQALQPEFFSVTYGAGGSTRDNTLEMVSALNQR
GVSVAPHLSFGGDDGATIAGMLQHYRELGISRLVALRGDMPSGMAGGGQLVHASELVRFI
REQTGDHFHIEVAAYPEIHPQAESYDSDLKHLKAKLAAGADSAITQYFYNVESYFYFLDQ
CAAIGIDKPIYAGIMPITNFANLARFSRNCGAEIPRWICQRIEGYGEDQDSIRQFGIEVV
SQLCQTLLESGCPGIHFYTMNQLEPTRQIRQNLAI
>E0PEE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus equinus ATCC 700338|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADTIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAREAAGDDAFVLGTVGALRGLKQCNLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITNLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEVELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKEANFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDGLADLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALEHFKGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A1C5ZL02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Eubacterium sp|TrEMBL
MNIREYLENHKLLTDGAMGTYFDSIEKENYICSEEANITNPALVREIHRSYVKNGAQLLR
SNTFLANEGTFLSLTQAKAEAFENITLKQLIIAGYQLAKETAQEVYQEEYPIFAAADIGP
ILEERDSEEADILQQYYEICDSFLEAGADIFVLETFPDTQYVLKMAEYIRKSCPEAFIIG
QFSLTPTGYSRTGFHYKTILQEATQSGLLDGAGLNCGVGAAHMKKFLKSYIEEFGVPEDM
VLTSLPNCGYPQIVRGHAVYSDSVPYFGEKLGEISELGVQVLGGCCGTTPEYIGEIYKTV
FQAKKTEGAVKIPTKIVWGDVTKRVQKRKEAAVHITQAGEQKEAIKEKQVTNTFRQKLEM
GELVCAVELDPPFDTDDTKLLNGAKALLSTKADIITIADSPLARSRADASLMAAKIKMTT
GMDVMPHLSCRDKNRIAIRSGLLGSYASGIRNYLFVTGDPVAREDREFTKSVFDFNSIRL
MKFAQSMNQEVFKDDTIFYGGALNQNGAGPENIAGRMLKKMEAGCRYFLTQPVYDKEGIE
RLTFLKERTGAKILIGIMPLVSRRNALFIKNEMPGIHVPDEVVAKYKEGASREEFEEAAI
EISKQIIEMGKGIGAGFYFMTPFNRVSLVKSILEYV
>A0A3R6XML3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. OM02-15|TrEMBL
MIRDYLKEHILITDGAMGTYYDQKKSENGRMAEEANLLEPELIQRIHEEYLESGAQLIRS
NTFAANRSLAIRKGIESKAEQDAYIRSVIQSAWNNAKIAVKRAAGEHFIAANIGPMPEYL
FLEYHCNPTEEYQFIIDCFLDCGAKIFNFETFSDITEVQEAARYIKEKCPEAFVMVSFAV
NRTGYTAGGISMNRLFTEAAKTPEIDSYGCNCMIGAAHMYDLLKAQNLSDEKFIQVLPNS
GYQEIVRGHSAYSEGASYYAEKMQKIAELGVNILGGCCGTTPTYIRNLSEMIAEHEPWEK
LHVAEKGTENAVSRTRNNPFMEKLQRGEKVIAVELDPPFDQNAQKLLEGAFRLKKSNVDI
ITLADSPLARARADSVLLAAKVSSMVDIPVMPHIACRDRNRISMHSTLLGAHINGIRNLM
IVTGDPVPSGERGNTKSVFDFNSIRFMEYINELNQDVFLQDSFSYGGALNQNLANTDKVI
ERMQKKIDAGVSWFMTQPIYSDEEVEKLARMKRELDTKILCGIMPLVSYRNAMFIKNEMP
GIHVPDEIVEQYRPDMSRAEAEAVAVDISLAVIDKLKDVADGFYFMTPFNRVELICRIID
KMEK
>A0A6H1U0E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxynema aestuarii AP17|TrEMBL
MTQQPLARSRFRLAVEAREFLVTAEVMPPKGSDASHTVEMARQLKDWVHAVNVTDGSRAV
LRMSPVATSAILLQHGIEPICQIACRDRNAIGIQGDLMGAHALGIRNILALTGDPIKAGD
HPKAKSVFELESVRLLKLIKKLNSGTDFNDNPLTDSPTDLFPGAAVDPQLKSWSGLKSRF
ERKLEAGAEFFQSQMICDFDRLDKFMNEIASGTDKPILAGIFLLKSAKNAAFINRCVPGV
HISDETIARLAEAKHPLREGMKIAAEQVQHARSICHGVHMMAVRREDLIPEILDMAGVSA
LTPQEAKIAV
>A0A4Y9ZDQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dentipellis fragilis|TrEMBL
MKISKKIEQAAKEDKVWWSFEYFPPRTAQGLQNLLDRIERMRQLGPEFIDITWNAGGRTS
DLTSELVKTCQGLIGIETCMHLTCTNMPKEKVDIALRDAKRHGCRNVLALRGDPPMGKDE
WEAVEGGFVHGIDLVRHIRKEYGDYFDIAVPGFPQMQLLPPEERALEMKYLKEKIDVGVN
LIFTQMFYDVDLFIEWVKTVREAGITVPIVPGIMPIQTWGGFQRATSLAKTIIPKSFSDA
LEPHKTNDEKVREIGTKLVADLCRRILAADIGIRGLHFYTMNLERGTKMLLEELNLVPRV
ETIKPLPWRQSLTPSRRSETIRPIFWANRTKSYLTRTENWDEYPNGRFGDSRSPAYGDLD
GYGVWIKQTKEDALKLWNHPTTFADLSSLFARFCKGELAALPWSDEGLLTETSVITSQLA
KINELGFLTINSQPAVDGARSDDKVFGWGPSNGYIYQKAYLEFFVLPELLDVLIRHIEKD
HSVTYHVINQRGDLRTNTTSDSPNAGHMGCLPWQGDCPAHDRGGDQLHGDEAYELGRQWA
KLYEPESESRKLIDDLMARALLVNVVHNDFKKPDAIFEPFLKAGAEYASLQANQTNGNGD
AH
>A0A1B9P2X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliivibrio logei|TrEMBL
MAYSHASHLESLNQNIAELNGCINVSFEFFPPSSEKMEETLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLIAAPHLTCIDASRSELIDIANDYWANGIKDIVALRGD
IPAGGGAPDMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQASRFAKMNNVRIPGWMAQQFE
GLDDDPVTRQMVGASHAIDMTRILSREGVKDFHFYTLNRAEHTYALCHTLGVRPDVNR
>A0A552FB43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa Ma_QC_Ca_00000000_S207|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDAAGIPPIHN
>A0A5F0FAN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT2-17-1|TrEMBL
MPHTSDPACRKIPFSFELYPPTSDAATSVLHATIERLAAAGPEFISVTYGANGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSNAESSQLIREFLDAGVRSFLALRGDPPEGIREGEAF
LGDLGSAAELVQLIHRVQAERVPYREAVIPGLPAARTIKREREKVRIAVAAFPNGHPRSR
SATQDIDALLAKQAAGANLAITQLFFHADHYLSFILRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRQATELARQLIAGGAPGLHLYAFNQHE
TVLAVLDGCGLLTPTLPASALPAPHPVKENS
>A0A221DWJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia marcescens|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLRDIATDYWNSGIRHIVALRGD
LPPGAGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A0F0LLA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium azadirachtae|TrEMBL
MSFDAPPFAPAGAVVPRVPISFELYPPRTTAPIEALHETIQQLASAAPRFISVTYGAGGS
VGGRSLDVLRYIREHTSVEPLAHLTCVGNTYAGASRLIREFLDAGILSFLALRGDPPLDE
SQPFLGDLESSAQLVQLIDRAQAERAPYQERPIPGVPGAVQVTPRRKVNIAVAAYPNGHP
RSTYRNQDIDALLAKQAAGATLAITQLFFHPDDYFAFVERARRAGVTIPILPGIMPITSP
ARLRRVLELSGEELPAELSIDLEVEPTAEGRTEIGVAHAAELVRELVDGGAPGIHLYAFN
QHRTVLDVLTAAGVLPEGGATSPTGGALQFAETSGAH
>A0A5D6WJA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp. mPRGC8|TrEMBL
MKRVSVELVPRDEETLRAELALLQQYQDKIDVINIPDLLRFETRSWQGAAMAKEYFPDAM
PHIRAMDINLEEELPMKDYLRAHDIREVLVIEGDPPQRMTHAVYPTESTDVIRKFREEMP
EVTVYAGIDQYRSSMRHELYRIHRKVQAGAKGFFTQPFYDRRLLEIYADMLSGLEVYWGV
SPVMNAGSQSYWERKNNVVFPQAFEPSLEWSVQFSREVMELADKMDASLYLMPIRTNLEE
YLAGVFR
>A0A831KQF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSETKTPSKLEKILSSGQLAVTSECGPPRGSDPEVIRKKAQMIKDHVDAINITDNQTSVT
RLCSLAACIHLKLMGLEPVLQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQKFGDN
PQGQNVFDIDSMQLIQTVRLMRDEGKFLGGDDIARPPKMFVGAAANPFADPFEIRVPRLA
KKVAAGAEFIQTQCIYNVDRFKEWLKGVVDRGLHEKVYILAGVTPFKSAGMAKYMKNRVP
GMDVPDELVKRMSGVPKEKQPEEGLSICVETIEQLKEVEGVSGFHIMAIEWEEKVPEIVE
RSGLYPRPSVGE
>A0A836XDP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Handelsmanbacteria bacterium|TrEMBL
MAQQTEWPPTDGKVKRHNGAFSRKIVDREFAVSVEILPSRGTAPKLLQAKIDFVRELAAS
GLADALDITDGSRGIPLMPPGDFIQLVRQGLGWTDATGDALELIAHFTARDLNVMGVQAR
LIGYWANRIHNAVFITGDPPKMAPNYPPSTAVFDLDSVDMIGLAHMHLNAGVDFGDQPLG
KHRDPRTRFTIGTGFEPEALEGKRELDKLQRKIDAGADYVMTQPAFRWEPLEAIRPFLED
VPVLVGVLILRGLDHALRMRDVPGVVVPDDVVQRLAASDDVQNQVRIGQEIAAEQIRHIR
ADGWSGLYLMSPASHKPVVDVLRSGLS
>A0A7L2Q4T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypocryptadius cinnamomeus|TrEMBL
MVNETQHTCSASSSSRSDGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIAYTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKQLGLKNIMALRGDPIGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVCAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGVVHGLHFYTLNQEVATTEVLKRLGIWDEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKTPREELLK
MWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLRVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6A6QXR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lophium mytilinum|TrEMBL
MEKVTDKIAALPSDAHYFSLEFFPPKTAMGFANLQNRLERMSRALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRSLVDDALEQAKALGIRNILALRGDAPRSEE
YRNEEKPEEEDSNNDFTWAIDLVRYIRKQYGDYFCIGVAAYPEGHSDQSHPQDQDPLFDL
PYLVEKTKAGADFIMTQLFFDVEAFDKFEKLLREHESGVFKTIPIIPGLMPIQSYQILRR
VTKLSHAKLPDKLLTRLDAVKGDDELVKQVGVEILSEVIDHVKTTPSPVRRGFHFYTLNL
EKAVAHILERCHLIPPIQPDEDEAVAVDFSKDFVPPEGALKSKHRRRVSSVNSGPRNRVV
VETHTKSSNTSFEAREDEAGVPRDPINTRANTLAISEGEGSLGREATWDDFPNGRWGDAR
SPAFGEIDGYGPSLHLPTPQALKLWGHPVTVEEVSNIFRRHISGDLDALPWSEEGLNPET
NTIRNELLRLNGKGWWSVASQPAVNGLKSTDPIFGWGPRNGFVFQKPFVELFIPSADWFK
LQARLDQTDQMTYFAGNKAGHFSASNEESVNPVTWGTFAGKEIITPTIVESVSFRAWLEE
AFSIWAEWQRIYPTRSATSKLLGGIMNDYWLVNIIHHGYLEKGALWDFLNED
>A0A5K1KYH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus altitudinis|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSLDEIKR
SFREQLYILLNEEPDGLLLETYYDIEEAKAVLEIARKETALPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPLLENSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSAIEFRNQGARIIGGCCGTTPQHISAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKSAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIREIMAKAGEDKEKQRTEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKEPNIHANYH
>A0A831NZM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLERVLASGAFAVTGELGPPKNSDPDIVRQKARILKGNVDAVNITDCQTAIVRMS
SIGAGLIAQSEGVEPVIQMTCRDRNRIGMQSDLLAASAMGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQMLGMVRDMRDGKKFQCGEEIKGPEPRFLLGAAANPFAHPFEFRAVRLGKK
VANGADFIQTQIIYNVDKFARFMEMVRDLGLHEKCSILAGVTPPKSLGMARYMK
>A0A831VLJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MTTQNKFSRSLLDPEQFTITYELVPGQGSGGRRHERLLEFARQTYEDGRIKALSITDNAG
GHPALAPIAIGSEVQAIGLEPLLHFSLKDKNRSQVESHLFLYHRQRFHNLLILGGDFPRP
NYYGQAKP
>A0A848YUW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MNENGLKSGSNLEKVLVAGHFAFTGECGPPKGANVEHLKEKYEHLRGMVDSVNITDNQTA
VVRMSSVAASAIMVGDGIEPNYQMVCRDRNRLAMMADILGAYSLGIKNMLCLSGDHQHFG
NHPQSKNVYDIDSIQLIAMTKLMRDEGKFPNGEDVDVPPKMFIGAASNPFGDPYEFRVHR
LANKIDAGTDFIQTQCIYNMPRFREFMKMAVDMGLTEKCYILAGVTPMKSARMAKYMAKF
VPGMDVPEELITRLEGAGKGKQAAEGIKFAVEQIEEFKEMEGVAGVHLMAIEWEHKVPEI
AEMAKVLPRPTFD
>A0A7C1C817|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
VWQYAKLLKKIAAGTNFIITQLGYDVCKLEELIRFLRETGNTLPVLGNVFIPSLGVAESM
GRGGVPGIVFPQQLIRRMQEEAVRQDTESRLLRAAKMICVLRGLGYSGVHLGGNGLNFAK
VRFVLDTAEAMQDQWPSLREDVHFPADNSWYLYPPSANGVCGKKRGALAPGRRQKAQRLH
QLTHRLLFAPDQSLTSRLFGRFCRYCAKSKGRTALLGKLEKAIKALLFSCRMCGDCTLAE
STYLCPQAGCPKKLLNGPCGGSRNMACEVYPDRACFWVRVYDRLDPGSGPEQLGAEPSLP
PKDWALDQTSSWINHFTGRDHKRLDPPPGDRPLRPGNEQGKQDQ
>A0A7W0EW22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MTTQFQKDIRNPEKFIITMELVPKAESSGRSIDAVLELAEGARKDGRLSAVTITDNPGGN
PSLSPDVLGSEILHNNMDVIIHFTCRDMNRAGMESRALQLMRMGMTNILALTGDYSGKGF
GGQSAPVFDLDSTHLLSLFSALNEKSIKKGNSSLIFPGCAVSPFKWTEAEAYAQYFKLCK
KTSSGAKFMITQLGYDARKFEELIRIQKLFQINIPVIASIYMLTPRSAKVMNSGKVPGAV
VHSDLLDIIKKEWAENKRNGYFAAIERAAKLAAIVKGLGYRGIHIGGVHRNFITVKRMID
RLGEIEDQWRSFLPEFDYPMDDQDYLFEKDPSTGLSMDQTVPQQTSGPGVCHQFHFRLMH
GLHQLFFSRASFLADFNKNLCQWIDKSRPATFGLKCMEDAFKKLLLSCQSCGDCGIQHAG
FLCPESKCPKHTRNGPCGGSRNGRCEVYPDKNCLWFMAYLRLSILGSTGEMAGEWVPPRM
WELNKTSSWMNFHLKRDHQGASFNLQNRMDGS
>A0A8J4ELN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinocatenispora comari|TrEMBL
MAAPTFSFEFFPPKTERGNELLWQAIRELEPLHPSFVSVTYGAGGSTRGRTVEITERIAT
ETTLTPMAHLTAVNHSVAELRNLVGRLAEAGVRNLLALRGDPPGDPMGEWVRHPDGVDYA
ADLVRLIREAGDFSVGVAAFPYRHPRSPDVASDTGYFIDKCRAGADFAITQMFFDADDYF
RLRDRVAAAGCDVPILAGIMPVTRMGIVERSEQMSGAPFPPALAAEFERVADDPEAVRQL
GVEQASRLCERLLAGGAPGIHFYTLNRSTATREVWHNLALPTVAAGG
>A0A315BXQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. JirII-29|TrEMBL
MTNNSLSIEFFPPKTAEGAEKLRAVRQALYVLKPQFCSVTYGAGGSTQAGTLSTLNEILA
EGVPAASHFSCIGATRDSVRQQLADFKAMGIRRLVALRGDLPSGYGGSGEFQYASDLVAF
IRAETGQDFAIEVAAYPEIHPQAKSAEADLQAFATKVKAGADSAITQYFYNSDAYFRFVE
DVQKLGVDVPIVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGFGDDLASIKAFGLDV
VTDLCDQLRSAGAPGLHFYSMNQSAATLAICRNLGLVV
>A0A3A4S0Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKHDSWLAKKIASGDFIVTAELLPQASTAIPEIEAAISFLGNSIAAVNVADNPHGPVLSS
LAGSLVLVKAGMEPVYQIVTRDRNRIAIQSDLLGAGALGIRNVLCLSGHHQTLTGSPESA
NVYDIDSIQLIAAVKQMRDQGVLLDGTEIKGVFPVLIGAVANPDMNPLELNILRLAKKVE
AGAEFIQTQAVFDVEAFERWIEQARNQKITENTAILAGVMPLSGYQDAETLRDHYMDLSI
PDSIIERLKKAGDEGAQKKEGLNICLETIRKIKKMDGVKGIHILSGGKEKLVPEIIASLD
>A0A351CDJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKVKTPSKLEKILAAGHMAVTSECGPPRGSDPEIIVEKANLIKDHVDAINITDNQTSVTR
MCSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAASFDIYNILCLSGDHQSFGDCP
TGQNVHDIDSMQLIQTVRHMRDEGKFLGGDDIKRPPQMFVGAAANPFADPFEIRVPRLAK
KVAAGVEFIQTQCIYDIDKFELWMKMAGDRGLLEKVAILAGVTPFKSVGMARYMKNRVPG
IEVPDEMVKRMADTPKEKQPEEGIRICIESIQRLKEIKGVRGFHVMAIEWEEMVPEIVEK
SGLYPRPSVE
>A0A3N5TR44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKPEELSNLQRVLSEGNFAVTAECGPPRGADSEAIRRKGAILKGYVDAVNVTDNQTAIVR
MSSIASCVHLFGMGLEPVMQMVTRDRNRIALQSDILGAYSLGIKNILCLSGDHQSFGSQP
DAMNVFDIDSVNLVNVVKTMKTDGKDMSGFALVNPPKMFIGAAANPFADPFEYRVIRLAK
KIDAGADFIQTQCVYNLDRFREWMRLSREEGLTEKVHILAGITPLKSEGMAKYMSKKVAG
MDVPEPVIKRMGGVPKEKAAEEGLKICLETVAELREMKGVHGI
>A0A3N5QKM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MHIKEIFKLYKTTISFEFFPPKSAKASEALYRTINDLIPIQPSYVSVTYGAGGSTRELTH
DLVVHIQKETDLTVVSHLTCVGATKEEILEILKKYHASGIRNIMALRGDPPKGQTVFESL
PGGFEYATELVAFIKKHFPDMGIGVAGFPDGHPATLNRLEEIDFLKKKVDAGADFICTQL
FFDNHDFYDFRARCELGGIGIPIIAGLMPITSFKNINSMADLAARVRFPARLLKALRRCE
TDAQVEQAGIHWAAEQVRDLLDHEVRGIHFYTLNKSTQIKKICDSLGLTHTPQFNK
>A0A2N6BTD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MNEKPISRLQKILTKGEFAVTAECGPPRGANPEVIRKKGEVLNAYVDAINVTDNQTAIVR
MSSIAACAHLLKMGLEPVMQMVVRDRNRIALQSDIMGAYSLGIRNILCLSGDHQSFGSQP
DALNVFDIDSMNLIRTVQTMRDEGKDMSGFDLNDPPAMFIGAAANPFADPFEYRVIRLAK
KIDAGADFIQTQSIYNMDRFKEWMKMAREEGLTEKVHILGGVTPLKSAGMAKFMNNKVAG
MDVPEAVINRMAGVSKEKAVEEGLKICLETIAELRDIEGVHGVHIMAIEWEDIVGEIVQS
AGLTPRP
>A0A542QJF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SLBN-118|TrEMBL
MTAFRSLLHHVRYEVLPARATQDKVLAHVPRDVVVTVTASPVKGLEPTLDLATRLAAHGY
RAVPHVPARLLRDGAHVKEVVHRLCEAGVDDVFVPAGDADAPAGPYEGALPLLRHLAELG
SPFARVGITGYPESHPLIDDDITIQAMWDKHAHATYIVSNLCFDARVLGEWVGRVRRRDV
TLPVYVGVAGPVERTKLLAMAAKIGVGESTRFLARHASWFARLAAPGGYAPERLLRRSAP
ALTAPSAAVAGLHLFTFNQIAETERWRRAMLDRIDGC
>A0A1F4R375|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division NC10 bacterium RIFCSPLOWO2_12_FULL_66_18|TrEMBL
MKFRDAYGSGKFGLSFEIFPPKMPAGEGALLEAIEALMAFRPSFVTCTYGAGGSTREKTL
ELTVAIRERFGVSTAAHLTCVGSSYEALRAWLAVAASQRIENIVALRGDPPRGESRFIPA
DGGPAHATELVAFIRREFPQFGVGVAGYPETHQEAVSPEADLAHLKRKVEAGADAVITQL
FYDNRDFFAFRRRYEQAGIRVPLVPGILAIINFAQVQRITTLCGAKLPPALVAQLEDRRD
DAEAELKIGVAHAIRQCRELLDAGVPGLHFYVLNKATAPARILEALDLPARAAGRV
>A0A5F0JCH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. BCA13|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAAQLATYHPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A523YJ59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSLQAKIKSGEFVVLGEFEPPKGDDFSRLLKNARQIKGRVDAVMVPEMGNAVMKASSLGG
CAFLQSHGIETVFQVCCRDRNRLALQADILAAAALGIPNIMAVPGEDITYGDHPQARLVN
DLNLIELLETIQKLQNGKDMAGVELSGAPSFCTGSTVNAGALGGVMDIEMQNLNKMINLG
VQFLITTPVFDLHRFQQFMKHVDTSKGAVIPTVLLLKSAGMARYIDRNIKSISIPKEMIR
DIQKAPDKLKQCIKLAAEIIGSLKDMGMAGVMISTVGWEDKLPQVLDAAKL
>A0A257RXM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 21-64-8|TrEMBL
MRVDQLLAEGLTRSFEFFPPKSDEESAVLDETLRELEPLKASFVSVTYRGGTASRQRTFD
LVTTIQREARTSAMAHLICVGHSRAEMRELLTRYAQAGVENVMALGGDAPEDPALARSEF
EYASELVELARDVGEFSVGVGAHPLGHPRSRDLVSDRRFLAAKLALADFAVTQFFFRASD
YFDLVAQLGELGVTKPVIPGVMPVTTLAGITRMATMGAAVPRELATRLENAHQRGGLGEV
RAEGIRAATQLCEELLSRGVPGLHFYTLNRSTATREIHGALFGTG
>A0A1M5TDP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporobacter termitidis DSM 10068|TrEMBL
MKAHEIMEKRMAFSFEVFPPKTDEGMTKLAGKGGVLEKLYKLKPDYISCTYGAGGGNVGK
NLEVLDAVKASGSVIPITHFTCIGNTHEGIKQQLQTYLEHGIDHMLALRGDLPFGWTGTG
GDLHYATELVKFVRDTFGDKFTIAVAGSPEGHIACRSLEADISFLKQKQDEGANFIMTQL
CWDMDQFRRWVDAIRKAGVTLPIDVGIMPVLDAAATINMALSRNGCVIPRALAEIISRYW
IFPNPFAPADDAADTKKAAFKEAGIEYTIRLIDEYRVCGIAGIHLYALNKYDDVARIVLE
SGIKDL
>G4UHF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neurospora tetrasperma (strain FGSC 2509 / P0656)|TrEMBL
MEKITDKVAALPPDSNYFSLEFFPPKTAMGFANLRDRLERMARGLRPLFVNVTWGAGGST
AQKSLELAEICQRELGLTTCLHLTCTNMSRRLLDKTLEDAKVLGIRNILALRGDPPRAAE
YHDENDPEPTDDEEFSWAADLVRYIKKTHGDYFCIGVAAYPEGHAEEAHPREQSLEHDLP
YLVEKIQAGADFIMTQLFFDIDAYEHFENTLRDHPSGAFKDVIIIPGLMPIQSYQMIKRT
TKLSHAKIPPALMARLDAVKGDDEKVKMEGVAIVSEMIERIKEIKSRTPGPRGFHFYTLN
LEKAVAFIAERTNLIPPGTPDEDESAILPDFPQLRINGSSVPTRSIQDLSTRKGSIGSDP
RDRVIVANQRPSHPDYEVSPLEAGLPAEPVNTRANTLAISEGEGVLGREATWDDFPNGRW
GDARSPAYGQIDGYGVSLHVTVPQALQLWGSPKTTEDINNIFIRHLKGELSAIPWSEEGF
NDETEAIRDNLIELNSRGWWSLASQPAVNGLRSDDGTFGWGPENGFVFQKAFVEFFIPSA
DWRVLEAKLRQPDMKDAVCFFATNAAGDFVSTDTINFRARMAAEAEGTAEADHRPHEPST
NAVTWGVFPGKEILTPTIIEEVSFRAWSEEAFGIWSEWAKIYGKGSDTQKLLEDLKEDLW
LVNVIHHDYLEKDGLWKLLSQ
>A0A3A4YQN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MNQESRLKSILEKGIFAVTAECGPPRGADPDAVLKKAGMLREKADSVNVTDNQTAIVRMS
SLAACAILKQAGVDPVLQMVVRDRNRIALQSDILGASSLGIRNVLCLSGDHQSFGNQPKA
LGVFDLDSMQFLQAVRAMRDSGLILGGEALTKPPRLFIGAAANPFADPMDFRVTRLAKKI
SAGAEFIQTQCIYNMDRFRKWLQLARNRGLTERVYILGGVTPLKSAAMARYMKDRVAGMD
VPQTIIKRMEGVPKERQREEGIRICVETIAELRELAGVKGVHVMAIEWEEAVGEILDRAG
LLPRPSLD
>A0A3A4PPB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MPSAFKKALDSGKFVVTCEAAPSKGTNLENMKHHIALLKDKVDAMNVTDHQSSVMRYPSL
GGALLVKEMGGEPILQMTCRDRNRLALQADLLFAASRGINNVLCLTGDSVMLGDHKDAKA
VFDLDSSQLVAAIRRLESGKDMAGNELDGGVRFCAGAIVTPEANPIEPQLIKFEKKIEAG
AEFIQTQAVYDLDNFKKFMEYARQFPVKVLAGVILLTSAPMARFMNKNVAGVTVPQDLID
EMASAPKGGALNKGIEIAGRMIRRIKEENMCDGVHIMAIGKEEKVIDIMAAAGL
>A0A875S009|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eeniella nana|TrEMBL
MKITQKLQQAQEDSSAPATFSFEFFTPKTSQGVQNLYDRMDRMYDLNPLFIDITWNAGGR
LGTLTTEMVNVTTTVLGLETCMHLTCTSMKLETINQALDSAFDCGCQNILALRGDAPLDG
SEFTGVFHYAKDLIRHIKSRYGDHFCIGVAGYPEGHPEERDVDKNIQYLKQKQDAGGDFI
VTQMLYDVDLFIDWCKKCRVAGITIPIIPGIMPISTYDGFIRRAKWCEIHLPDHFLKRLE
PIKDDDSMVREEGAKLVAEMCEMLLESGYIKHLHFYTMNLEKSCVMVLRHLGLVSKQQLV
GMDTKPWRRSLNPNRSLESVRPIFWQNRKFSYIERTSNWDEFPNGRWGDSRSPAFGSIEL
SGHQLIRHTREKALSLWGFPTGIKAITDLTVKYLSGDINCLPWSDSKISHEIDPIKSDLL
DLNRRGVLTVNCQPSINCCPSSNKVHGWGPGNGYVYQKQYLEFLIPTAKLDSLVQEINAI
NNEAEYHVLTYYAIDEDGDFDSNAKSASTINAVTWGCFPGKGVAQPTIVEKISFIAWKDE
FFSILRKWTSLFKNDDDLKRDQATTFVDSLINEFTLVNIVDNDYVNQPNTRIFNVLKKLF
PLKE
>A0A875SER0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eeniella nana|TrEMBL
MSVRITDKIGTLSEDEPFFSFEFFPPKTEHGTRNLYARLGRMSLMGPLFVTVTWGAGGTT
LRKSMDLAITCQKELGLTTCLHLTCTNTTKKVIDDTLRKAKENGICNILALRGDPPRGSS
LSHDCGDFEHAVDLVRYIRQQYGDYFCIGVAGYPEGHADGFYDQSQNPTKDMPYLVDKIN
AGADFVMTQLFFDVDSYLKFDKLLRSQSDLVNKRITVIPGLMPINSYNVFQRATKLSHAS
IPDSVLDRFPEDIQVDDDKVKEIGVTIINEMIAEIHEKTGGKTKGFHFYTLNLEKSIAQI
VNQSSILNKVVEKKEKEVEECVSESSDEDIDDSTTTAKRAAYMSRFKQPTNQIIVDSKKN
PVKSAKMGTPARRRSSSSQFRKIMSISSGHGTMGKDATWDDHPNGRFGDTRSPAYGASVY
GPSLSVTSKKAYELWGHPTSLDDISQVFVNYLSRKVDSIPWNEMSISPETALIQEQLIQL
NKHHRFTMSSQPASNCSKSNDKIFGWGPAHGYVYQKAYVEMFISKEDWEKRLVPKLKVNP
NISYYVADNKDYFESSMKPQDTNCITWGVFPDRQIVQTTIVGEDSFRAWKEEGFEIWREW
MLLYLKGSPSANLIQKVLDTYVLTTIVHHDYPDVGALWDLLLDED
>A0A2H0ABW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG23_combo_of_CG06-09_8_20_14_all_60_8|TrEMBL
MKSGSRLERILARGEFAVTGELGPPKSGDPEVVREKARLLKGSVDAVNITDCQTAIVRMS
SIGAGLIALQEGVEPVIQMTCRDRNRIGMQSDILGAAALGLKNLLCLTGDHQKFGNHPMA
KGVFDMDSIQMLGMVKAMRDDQVFQCGEAIKDHAPKLFLGAAANPFAHPFEFRAARLGKK
VAAGADFIQTQIIYNVEKFARFMEMVRELGLLDKVHILAGVTPPKSLGMARYMKKFVPGM
EVTDEVIKRMQGAKDKEDEGINICVDIINQVRAIQGVAGVHIMAIEWEKAVPEIVSRAKL
GPRPVFADDGTAPPLAAARQPGATAAVPMVLRGPIAGEQPGIPEGDDAGEHAMNERERQI
ALEQVRGGLEALKEALGISDKQFEALTKFTAACATLEKEPPAGVAAVTAAAPPPVKVEAK
VVEKAVEPKAAEVAAKKAAAEAASKAEAEKKAAEEAARQKAATEVASKKAEAEKKATAVA
ASKAVPAPKEAPPAKPPAQPAVKPSPRSSAAETPAALAVETTPLAERAARVPDNSYKQVY
SGAIRETVLGSKGHTLTVGGAKTLPFYLFEGEMPNRPIVAMDVLDVAPDEWPASLARHFE
GVLNDPVAWARKCVTDFNMEAICLSLVSTDPNGLNRPSSEAAKKAVEVVNGVDVPVILWG
CGNADKDTETLREITAMIGDKKVCLGPLSDANYRSLGATAMAFGHPMIAASPIDVNLAKQ
LNILLENLGVSLDTVLVDPSIGALGYGIEYSYSVMERIRLAALTQKDEKLQVPLICNLGR
EVWKAKETRLPTDAMIGDQERRGVLMEAITATCMLMAGGEVLIMRHPRAVALTKALISGL
MG
>A0A1Q6WKK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium 13_2_20CM_70_9|TrEMBL
MTITLRDLLNDGKVHVLDGAMGTMLYSKGFFLNVCYDELNLKQPKLVQEVHAAYVRAGAE
ILETNTFGANPVKLGSFGLADDTEKINQAAAELARAASGGQTSVVGAIGPLGVRIEPFGA
LAREEAFAHFQRQVTGLVAAGRGVDGFILETFSDVDELHEALRAVRSLSDLPVIAQMTIG
DDGLTHYGTAPETFAQQLAEWGADVIGVNCSVGPAGVLEAVEKMVKVTDRPISAVPNAGL
PKDVGDRKIYLASPEYMASYARRMIEAGARIVGGCCGTTPEHIKKIRDYVASVVPRHQPV
VVSREAVAPPAGVAAVPLARRSCFGAKLAAGQLVTSVEIVPPRGVDPAPMFAQCRALKAA
GVDAVNVPDGPRAQSRMGALLSSIMIQREVGIETVTHYSCRDRNLLGMLSDVLGAAAAGL
RNILIITGDPPKMGPYPDATAVFDIDAIGLTNLVYRLNHGLDPGNNPIGQPTEFAIGVGV
NPAAIDLDRELSRFAWKVDAGADFAVTQPVFDPKQLADFLKRVEQFRIPIVAGIWPLVSL
RNAEFLANEVPGVSVPETVLARMKQAQEKGKEAALAEGVAIAREMFQQVKGAVQGIQVSA
PFGRVEVALEVFGG
>A0A2E2NJX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citromicrobium sp|TrEMBL
MTAGPGTMFDPAREADYATTPPLFSGLPGDIDVSFEFFPPKTEKMEASLWNAIEELKPLD
PHFVSVTYGAGGSTRERTHKTVARIIAEAGLPAAAHLTCVNASKKETQRIAEHYWEAGVR
HIVALRGDMPREDGMLGPFEPHPDGYANAEELVRGLKEVADFEISVSAYPECHPDAQSPQ
AEIDYLKRKIDAGADRAITQFFFSPETFFAFLEKTDKAGIDVPIVPGILPITNVAKAREF
AGQCGAEIPQWMDXLFEGLDQRPAARQLVSATIAAEMCRRLYAGGIRHYHFYTLNRADLA
YAICHLLGMRPTENPA
>A6TPR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkaliphilus metalliredigens (strain QYMF)|TrEMBL
MSLLKDVLERGEFGVTAEMAPPKGTDLSHLLECARAIKGRVHGVNVTDFQSAVLRVTSLV
TCKLLKDEGLEPILQVTGRDRNRIAIQGELLGASVFGIENALGLTGDHTVVGDHPQAKPV
FDLDSVGILQAATTLMSGKDMVGIELQGTPTFYLGACVTPRFDPMEAQILKMEKKIKAGA
KFFQTQAIYDLDTMREFIEKTKHLDTKILAGIIPLKSAGMAKFMNNNVPGVFVPDELIER
MKNTPKEERVEEGIKMAGELIRQLREEGLCDGVHIMAIGAEENVPRILDAAGL
>A0A396MLV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. AF10-3|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTSSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>A0A1I4QMM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. cf124|TrEMBL
MLATGKTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSVTYGAGGSTRSGTVKATEQ
IAADTTLTPVAHLTAVSHSIAELRNIIGQYADAGIRNILAVRGDPPGDPMAEWVAHPQGL
TYAAELVQLIKESGDFCVGVAAFPEMHPRSPDWDSDVARFVDKCRAGADYAITQMFFHPD
SYLRLRDAVASAGCETPVIPEVMPVTSVKMLERLPQLSNAAIPNALKERIVTAKDDPTAV
RSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGLHHPPRA
>A0A326GB67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citromicrobium sp|TrEMBL
METPLFSGLQGDIEVSFEFFPPKTQKMGETLWHSVETLAPLGPRFASVTYGAGGSTRERT
HEQVVRIQNEAGIPAAAHLTCVEATREEVDEVARHYWAEGIRHIVALRGDPPDGSSQYTP
HPGGYANAIELIAGLKQVADFEISVAAYPEVHPDSPDRQADIDNLKAKFDAGATRAITQF
FFDPQCFFEFRDKAAAAGIAGEIVPGIMPVMSFAAVQRMSGLCGTAIPDWMEGLFDGLDD
RPEARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKVVV
>A0A286HW27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea halophila|TrEMBL
MTSSFRSSAEALSERIKVSFEFFPPKNGDMESQLWESISRLAPFQPDFVSVTYGAGGSTK
QPTLNTITRISKETDLAPAAHLTCVGSDKASVDAVAREFQAVGVNHFVALRGDPPEGVGA
AYKPHPNGYANGAELVAGLRAIADFEISVSAYPERHPESPDFATDIDMLKRKVDAGATRA
ITQFFFDNDIYERYVERVRRAGIYIPIVPGILPIHNFGQVARFSKLCGASVPDWLARRFD
GLEKDPDTRALVAAAMAAEQVNDLVERGIDDFHFYTMNRAQLVYAICHMLGLRGDEAGSG
ESGSVGAAA
>A0A417JTZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium AM26-1LB|TrEMBL
MKISEILKNKSTISFEVFPPKNKEGDISSIYSTIDGLAKLSPDFISVTYGAGGSTKGKTV
EIASVIKHEYGIESVAHLSCISSTKEDIKYECERLKEAGIDNILALRGDYPADAADFDPE
NLEFHYASELNEFIGEHFKGQFCLSGACYPETHQEADGFKKDLEALKKKVDAGAEYLVTQ
IFFDNDYYYRLVREARKIGITVPILAGIMPITNAKSLIRTTKMCGCTIPYQLSTMIEAHY
DNPEAMKEIGINYAAQQIIDLITNGVDGIHIYTMNRAETAQRVFESIPAVLKELN
>A0A1H3FV68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas sp. Nm33|TrEMBL
MKSQKAFSPTFSFELFPPQTPEGVEKLRAARRQLAQFKPKFFSVTFGAGGSTRDRTFETV
LEILAEGHPAAPHLSCIGSTRENIYSILRKYQENGIHHIIALRGDLPSGMAQPGEFRYAN
ELVTFIRNEFGNTFKMDVAAYPEYHPQARSVQEDFRNFRNKIEAGADSAITQFFYNADAY
FHFVDMCEAANLNVPIVPGIMPINKFSQLVRFADNCGAEIPRWIRKKLEGYGDDIASIHA
FGLDVVTDLCERLLKAGAPGLHFYTLNSAVLTTKIWQRLGL
>A0A2E7UDT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citromicrobium sp|TrEMBL
MTAQPTPALDPAREETRAKDDPLFSGLPGDIDASFEFFPPKNEKMEESLWNAVQELKPLD
PHFVSVTYGAGGSTRERTHKTVERIISEAGLPAAAHLTCVNASKKDTQRIAEKYWEAGVR
HIVALRGDMPQEDGTLGPFEPHPDGYNSAEELVHGLKEVADFEISVSAYPEMHPDAQDQQ
TEIDYLKRKIDAGASRAITQFFFSPNTFFDYLEKTDKAGIDVPIVPGILPITNVAKARLF
AGQNGAEFPDWMDDLFEGLDDRPSARKLVAATVAGEMCRRLYAGGIRHYHFYTLNRADLA
YSICHLLGMRPKGGQETGQ
>K8WCW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia burhodogranariea DSM 19968|TrEMBL
MSFFHANHREALNQNLAELDGQINVSFEFFPPRTEEMEQTLWKSIDRLKTLKPKFVSVTY
GANSGERDRTHTIIKDIKDKTGLLAAPHLTCIDATRDELREIARDYWNSGIRQIVALRGD
LPNSSKKPDMYATDLVELLKTEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVEGYLRFRDRCVSTGIDVEIVPGILPVSNFRQLERFAKMTNVRIPSWMSKMYE
GLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A2U1CVN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tamilnaduibacter salinus|TrEMBL
MTNEAVMESQKQFKRRFSFEFFPPKTDKGEEKLQKTRDRLAELNPDFFSVTFGAGGSTRD
RTLETVTRLHSQGISTAPHLSCVGATRESIAELLDLYRENGVERIVALRGDMPSGMGGAG
ELRYANELVEFIREHSGDYFNLEVAAYPEFHPQAPTAEADLQNFVRKVKAGANSAITQYF
FNADSYFYFIDRLEKMGVTIPVVPGIMPIVNYSKLVQFSDMCGAEIPRWIRKQLDAYGDD
TESIKQFGEDVVTRLCEQLLDAGAPGLHFYTLNQANASTHIWRNLGLDQSKRIAF
>A0A5R9MP51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. KGMB03662|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKKRVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A8D5XIY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas testosteroni|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A7Z9UUA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MRTWQKPSFRSLLQKTSIFVTCVELVNSRGVITERKGTRILKLARELSQNPQIHALCITS
NAGGNAMLSGDTLGTDLISRGQEVVIHLSCKDWNRNGLQSQAWKLASEGFNNVLALSGDY
PVSGYQGQASAVFDIDSVGVLKMMSEMNAGLKISAGQKKKDRVLKQTSFFLGAVVNNHKQ
YEREVMPQYFKLKKKIENGASFIINQIGYDARKQDELLKYMDWSGLHVSVLANVYVLSLT
AARFFHANNIPGVTVTDDLLALIEKQAGSSDKGKTFSLEFAAKQCAIAKGLGFRGVYLGG
HLKSSDYERILEIADQFGEDDWKDFSKEICFHQTDEFYFFEPDTSTQLSSTEINREYLHS
KSLKALQVSKQNIPLSYKINRVVHDKAFEKGTLGFGLGKKTSQAIERTNKGVQKILHGLE
QTFKMAAFGCQDCGDCSLPDIAFLCPESQCAKNQRNGPCGGTYQGKCEVGEKECIWSLAY
DRLKAYGQEEQMLNGPAIFKDGSLKGTSAWINTFLERDHHGNGKKQMES
>A0A8A1UJ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM 4667 / NRRL 2234)|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVQHPEGVLYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATQLCARLMAEGSPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A853VRY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia sp. HvH-WGS333|TrEMBL
MKVTEHIAQSKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGEKYFEPTKGGNRYASDLVTQINDLGKGKFLHGEISGNDLNNSFCIGVAG
YPEKHLEAPSMQYDLKMLKQKVELGADYVVTQMFLDNQKYFEFVKLAREAGIDVPIIPGI
KPLAVKKHLQLLPQVFKIDIPEDLVNAVSQCKNNEAVKQVGIEWCVQQCKELLDFGVPAL
HFYTMGKSDNIQKIVSEFF
>R5R8D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis CAG:558|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLYQRNRLRRRPGTVAVAAAIQNKYNMTVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGHHHALELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIHWLKKKVEAGAEYAVTQLFYDNKKYFDFVERVHQAGIHIPIIPGIKP
FKKLSQLSMVPKTFKVDLPEELTQEALKCKTDEEARKVGIEWCINQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A2U3QBP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium vignae|TrEMBL
MTDATTPGQANGQDGHLKRPAISFEFFPPKTEEMERNLWETIKRLAPLEPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDAIVDRYHEVGVRHIVALRGDPVG
GIGTPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDA
GATRAITQVFFDNDFYFRYLDRVRARGINIPVVPGIMPMHNFKQARNFVTRNGTTVPDWL
AAKFEGLDDDAETRKLVAATVVAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
TAQKAA
>A0A370I591|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia pseudobrasiliensis|TrEMBL
MGALRKRPDGAIPFSVEFNPPRDAAAEARLWRAAREFERMHPAFVSMTYGAGGSTRDRTA
RVTGQLARETTLLTVAHLTAVGHSVAELRSIMGTYADSGIRNLLVLRGDPPGDPLGEWHQ
HPEGLAYADELVRMVRELGDFHVGVASFPQGHHRSPDLDHDTRFLCAKLRAGAEYSITQM
FFEVDDYLRLRDRVIACDPIEGAKPIIPELMPITSLRTVQRAEELSGRALPPALMRRLER
AAGNDPERNRDAVRAVGIEIATELGQRLIDEGAPCLHFITLNFAKATSEVLTNLGYTMSA
APVSA
>A0A2E7FPL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutaceae bacterium|TrEMBL
MSKQHTIAELLSIGRPLLSVEFFPPKSEESIDLLVGAGKRISACNPDFVSVTYGAGGSTR
DLSAAVSKRMKDEVGLSVMPHLTCVGSTQEELGEIVDDFYAEGYRNIMALRGDPPNGQSD
FQVTQGGFKYASDLVAFIKDRHPDICLGIASYPEKHPEAASLDADLDALKIKADAGGSFI
TTQLFFENAAYFKYIDQVRARGIELPVFPGIMPVLALKQIKRITQLCHSELPAELEAKLS
AVESDPEAVRRVGVEWAMRQVGELIEKGAPGVHI
>A4ESH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseobacter sp. SK209-2-6|TrEMBL
MEHNSSQPYAPPPEGHVSHSRLERVLRSGRFAITAELNPPDSADPADVFDAAQPLGEVAD
AINATDASGANCHMSSIGISALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAAMGVSNVL
CLTGDGTGAGDQPGAKPVFDFDSISLLRTIKTMRDEGRFLSGRKITKPPHLFLGAAENPC
IPPYDWRPQRLAKKIEAGAEFIQTNYIYDIPLFERFMERVRDLGLDQKVYILAGVGPLAS
ARAARWMRSNVPGIQIPDSLIERMERAEKPGQEGKKICVELIQKIRDIAGVSGVHVMAYR
KEHLVSEIIQDSGVLATRKRR
>A0A660UAE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MARPFRETLKTKDFIVTAEVGPQKGTDTSKLIEHIDLLKDKVDALNATDNQGSVMRYPSV
GACMLIKERGGEPILQVTCRDRNRLAIQADLLLAYSRGIDNVLCLTGDSIDVGDHPEAKP
VFDLDSVQLIHLVHNLNSGRDMAGNELEGKTDFCIGTTGTPSADPIEPQLIKFKKKLKAG
VSFVQTQAVYDLDQLKRFVEFARKIDDKVRILAGIVPVISARMAEYMNENVPGVFVPQWI
IDELAKTPKKGRIKKGIEIAAGLIRQIKEEGICDGVHIMFIGREERIPEILEAAGLL
>A0A2I1RJ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella osloensis|TrEMBL
MTTPFSFEFFPPKTDDGQTKLLATFDELNALKPQYFSVTYGAGGSTRERTLGIVKALSEK
SDTPITPHLSCIGDDKAKIGELLDYYKSLGINRLVALRGDLPSGMVGLGELPFAVDLVKY
IREHSGDYFRIKVAAYPEMHPQAKSFDADIQNLLNKYHAGATEAITQFFYNADSYLYLRD
ALAKKGVTQDEFPIIAGIMPITNASNLIRFADGCGADIPRFIRKQLADYGDDKKAIRQFG
FEVMVNLCERLIAEGVPSMHFYSMNQVSPNKQLIEALGLV
>R1GRG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grimontia indica|TrEMBL
MTMNFEQGKVDCMPQLPDPAFAAAELIYHASLEATPRQVSALENRPEWLPEGIRVYVPFL
PSSNFEDAFDTCKTLLIWGAVPVPHLPARAVPSEEKLREWLLALKVLGVKQLLLISGDIE
TVQGPYADTMQLLQSGLLQEYGIESFGVAGHPEGHPHADQTTLKNALEFKRNYAKEHGLS
LWVVTQFSFDQTVLEQWLDEHQTILAGIPVYLGLAGPTRLKNLLSYAAQCGVATSAKALT
KNLNAVRLLRPWTPDALLEGMAVYQSNRSESVLKGIHLFPFGGLKQSAEWLANKAR
>A0A0E2BTJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus casei A2-362|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A542ZA70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rarobacter faecitabidus|TrEMBL
MTDKDHDCWDPTQLRPTISFEVMPPRRPDIAPNFWSNVDRLIGARPDFLSVTYGAAGTDR
QTARQVVSRLIGSAPLLPIAHLTCVGHSRADVVEVVDEFLSAGVRSFLALRGDPPAGQPD
WQPTPGGVNSSVELIALLRDRERVRCAAHPGNALRGAAQPLTIAVATFPGGNPSAGTSSD
QEIERLLVKQAAGANFAITQLFYRPETYADFVDRARAAGVHLPILAGIIPSTDPARLHRV
AELTGLQPPPELLKTLAEASSDEARHEAGVRATTDLARAVLDAGAPGLHIYTFNKATPAL
DVLSGLGLTTDTTTTSTPTEPVTAPAVVKG
>A0A2V4F9P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SMT-1|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIREETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A499V4E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces antimycoticus|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRADLRNIIGQYADAGIRNMLALR
GDPPGDPTGEWVRHPDGLNYAVELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATEVCAQLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>A0A2A8HC18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus toyonensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTNRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQVALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMINEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6P4QDL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium arboreum|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNECRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGVKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQYPYGRWGDSRNPS
YGALTDHQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSYCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGTTDVNAVTWGVFPAKEIVQPTVVDPASFMVWKD
EAFEIWSRAWAALYPEGDPSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>A0A7X2EMR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAVGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A845SG02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Fonsibacter ubiquis|TrEMBL
MNKDLNISFEFFPAKDEAGHENLWHSLEKLEQFSPKFVSVTFGAGGGERDKSDFLVKKIS
KKSNTPVAGHLTCVDMSKNEINSIALDWLNNGINKIVALRGDVRKKDSKYMPHKNGYENA
ADMVNGLKKLGNFHIAVAGYPEKHPDSENETKDLENLKNKVDQGADKIITQFFFNDEKFL
KFRDKAISLGIKIPIIPGILPIDNFEKIKNFSKKCGTSIPIWVEEEFAGLENDNEVQKIV
GASIACDLVKKLQLEGVNEFHFYTLNKYELSYAVCKRLIADKTKIKINQLKELNV
>A0A2T7YWL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8H7BT05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apophysomyces ossiformis|TrEMBL
MKIIDKIKKAEEEGRMYWSFEYFPPKTAQGVQNLFDRIERMQRFGPEFIDVTWGAGGTTS
DLTSEIVATTQTVYGVETMMHLTCTNMPVEKIDEALEKAKDAGCQNILALRGDPPHGQNN
WEACEGGFVHAIDLVKYIRKKYGNYFGIAVAGHPEGHVDNPDKEADLIHLKEKVDAGADL
IVTQLFFDVDIFIDFVKRCRAIGITCPILPGVFPIQNYNGLSRVISFNNNYVPQKIWDDL
QPIKDDDAAVKEYGIQLTIDFIKKMQDTGVKGIHFYTFNLERSTRIILERLGWVPSQENV
KPLPWKPSLHSKRTKENVRPIFWKNRTQSYIKRTELWDEFPNGRWGDSRSPAFGDLDGWG
VSLKRPAAECLKVWAHPTTEDDVVSIFSRYCLGQVGFLPWCSHELEPESANIRHRLAAVN
KLGYLTINSQPAVNGAKSSDKVHGWGPKNGYVYQKSYLECFVSPEKLGELVQKIGGDGRV
TYYAVNQAGDLKTNTQSDGPNAVTWGVFPGKEIIQPTVVEAVAFLAWKEEAFALWNEWAR
LYEPASPSNSLLKTIADSWYLINIVHNDFHDELALWRLFGLEDDSAVSNLIGVAPR
>A0A4Q1F9H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. YO64|TrEMBL
MKVTEHIENAKGNTLFSFELIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNHFAIDLVKQINDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRFKEKVDAGADYVVTQMFFDNSKYFAFVEKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVYKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A093GZM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dryobates pubescens|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKNDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEEDLKYLKEKVFAGADFIITQLFFRSETFFK
FVKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKALKKYESRVNY
HIVNVQGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A2H6B3Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR40|TrEMBL
MNRDLIELYEPILRARSPELPLPPFTLSVEVFPPRTPEATVAFWQELGEMREVAPAFVSI
TCGAGGTGRDGTFPLALEVRRRLGLEVAAHLTCAGHSRAEVDALAEAYWQNGIRRLVALR
GDPPRGSGPYRPRPDGYAYAVDLVRGLKAIAPFDISVAGYPETHPEAPDPEFDLDNVRRK
VEAGASRVIGQYCFDTDRILRYRDALIARGVSVPFVPGIMPIHSFAQIARFSARCGAAIP
DWLARMFEGVPEGSTLHTMLAASVVAEQVRRLVREGFRHFHVYALNRAAPTRAICRLLDL
PAVREAAA
>A0A066PT21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiphilium sp. JA12-A1|TrEMBL
MSHTPPRAVLERWLSGPRVDPLPTPALRAPAPAISFEFFPPKTETLEAQLWACIRRLEPL
APRFVSITYGAGGSTQERTHATVTRLVRETTLVPAAHLTCVGASRGEVDDVARRYWDAGV
RHIVALRGDPPGGTAYAPHPEGYAYAADLVAGLRRVADFEISVAAYPETHTQAPSPQADL
DNLKRKLDAGATRAISQVFFETGHFLDFLDRALAAGITAPIIPGIMPVSNFGQAKRISEM
AGTHVPAWMGEMFDGLDDDAETRKMVAASIAAEQVRTLQANGIDEFHFYTLNRADLTYAI
ARILGVKPAR
>A0A2N2XFK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-23|TrEMBL
MKVTQHIENANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPSGLLQKKIVKKRPGTVGIC
>A0A1G1PDR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium RIFCSPHIGHO2_02_FULL_68_15|TrEMBL
MRLDQLYRGSSPDISIELFPPKTPEGVEALFQTVESLKRLTPAFFSMTYGAAGSTRDTTL
ALCDRLKNQAVVETTCHLTVVGQSKADVRENLARLKTMGIANVLALRGDPPAGVSAFRPH
PDGFHTSVELVREARRDPWFAVAVSGFPEVHQEAKDRAADIAYLKDKVDAGACVILTQLF
FDNAYFFEFLEHVRRAGITVPVVPGILPILTVAQVRRFTALCGSTIPPAVARELAKYEQD
DDGAGRYGIELAARQCEELLKAGAPGLHFYALNRTRSVETVLQHLRLVR
>A0A417IDH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. AM28-10|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A2P2BUI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Romboutsia hominis|TrEMBL
MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAANVTDFQSAVMRTTSLA
TCKLLKDVGLEPVIQMTGRDRNRIAIQGEMLSAGVFGINNMLALTGDHTVVGDHPQAKGV
FDLDAVGILQTAETLMKGTDLVGNALKGSPEFFLGASVTPEYAPIEVQLLKMQKKINAGA
KFFQTQAVYDIEHMREFRKLTRDMDCKVLAGIVPLKSPGMAKFMTANVPGIFVPDDQIER
LRAAGKENWVSEGIKMAGEFIRQLKEEDLCDGVHIMAIGAEENVPAILDAAGL
>A0A5S6PGA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brugia malayi|TrEMBL
MDAVRDDNEGEMSPTSSTDGVVIPRSCSKKWGESRTDWVANGTYVPLRDRIKKRIANGIP
FFSLEFFPPKTTNSVANFFARLDRFREGNPMFVDIAWHFGSDPGNISSETSSSSVAAGCL
DYCGMDTMLHITCCPYTKEQSIRHLEQSKALGLKNILALRGDLPRQDENPVLYKYRALDL
IRWIKEEYNDYFTIACAGYPAGHPEAPSYRADLLYLKAKVDAGADFIISQIIFDGEVFKN
FLRDCREIGITVPIIPGILPIQSYESIRRVAELSQLVIPDSILTSLEPIKNDDDAVRNFG
IWHAVTLCRTLLSNGSATSIHLFTLNREASSREILQQLGLWPRSPMRALPWRLFGESHPV
RCKEDVRPIFWSMRPKSYVFRTREWDEFPNGRWGNSSSPAFNDLKDYYLFYLKGQPTRDE
QLRMYGERLETLADIQKVFVNFITQNINENGVKVSQLPWNEQHDGIRAETSLIKDQLLWC
NSNGFLTINSQPSINGAPSTDPFVGWGKPGGYCYQKAYLEFFTSQANAEVLWSLLPSYSR
LNCHIVNHDATIDWTNTETTMPIAVTWGVFPGSEIAQPTVVDPLSFRVWKDEAFSAWLNW
SSIYAEGTSSRCLLEKIYNEYCLVTLVDNDYPKSTIIFDCLAQLVNR
>A0A0C5EMA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MRSN12121|TrEMBL
MTLLNKALSEQSFVCILEFVPKPDARRFAAVEALMARSQLCDWPLTLAIADRVGNPLEMS
PLEAFRSLGQPVPALLHFSGKDRERQDLLAQLPLMDAAGVQQLLLLTGDRLSGHRPGQRP
VRYLESVAALQSVRQARPHWWLAAALNPFKYREEEGGAQYFKAEKKLAAGADCFMLQLGF
DAQKHLEAIAWMNRQPNPKPLIACILALTQGRARMLDQVAGVVVTPSMRALVDAEAAVSK
HYARERSIERLALQAIGLKLMGYAGINLSGIHDLDQLLALEQAINAWQPRVPSLEQWRAA
WDAAWRMPGLGPVSFHPVEANWQLGESRVGASPRERARYHLLHGMHSLLFDRSTWTSRAF
GWAVRRPLWSSTTGALWLHRLERGLKRPLLGCDTCGSCRLEDTLYICPETCPKGLANGPC
GGTSLNRCEFGDRECIHSVKYRTAKAVGQSAVLSQRLIPCVEVGNRHRSSWPRWFDNPPS
TAQAPRHERDNAGTVAVSKD
>A0A832FKZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKAGSRLEKLLIQGEFVATAELGPPKSADIQLIKHKAGILRGFADAVNITDNQTAIVRVS
SIAAGKIALDEGLEPIIQMTCRDRNRLAMQSDILGAYVLGLRNLLCLSGDHQSFGNHPQA
KNVYDLDSIQLVQMAKRMRDEKVFQCGEEIRNTKKSDLLEPRMFLGVAANPFADPFEFRV
VRLAKKIKAGADFVQTQCIFDLPKFKRWMEMVVDQGLHERVFILAGIMPIKSPKVLQYMK
NNVAGMSIPDELIRRMEGAKDAKAEGVKICVELIQAVREIPGIRGVHIMAVEWEEIVPTI
VREAGLWPRPEVAAE
>A0A7C7GFR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
GAGGSTRRLTVELCVRAYRDSGVTVMGHLTCSAQTKEMVHSVLERFESEGIENVILLRGD
PPQGEDTFVPEAELNVVHEFVHHLQQLHFETAATLESISKNADQTAAYRALIEGDASLSH
LLYMSEYLETEEQAAAQDATGITDVTAFLAAPYVIQQLTLFPYVEGRFFAIELYLRDQDF
ALIDQAFEYIPRSTEQIIHVDKYDSREEPVEVVLPDIAATLGEEWMEFDRDTMGELFIRS
YFESVIGVETATSTLAAAGWGGDQYALLENEAGQTVFASLIVWDTEQDADEFYRAYQELV
ELRTGGFWEDFEILGVESSLALATTSQYAIVTLDGLVTVNVLSHDLDIAATTTEFLISAF
SRRMPLAEFGSGVHQVNIDIQPGTYRNSDSSPGCYWARLSGFDGEVGDIIADENTDEITM
MTISDSDVGFESKGCGSWTMVDN
>A0A7X7JRJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MDALFGTPYVIELLTPKQSDEDFEARLEVFAERYQRILDEGAVVSIPDNPMGNVHFTALE
VVEFLDLPLHSERTLLHLNSFHLKNDLEAFLKGAADRKVKHLLVVSGDGGPKLPRLEPAD
VGIDAKTVTSTVLLQYIEREYPGVFTCGVAFNQYEPAEHELGRLERKLEAGARFIITQPV
MGADAVVASLQRFGVPVFIGAWMSKRVDLLLECVGLEPRQDEQYDPAANLGQLNRLYPDF
GLYLALLSFKRDWSDLLTRRLPHAAGWPPAATL
>A0A6H9HN84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MPDVAATGVAPPPVKVSFEFFPPKTAEMEASLWRAVQRLAPLQPRFVSVTYGADGSTRDR
THNIVRRIVRETGLTCAPHLTCVGASRDEVLEVVRGYRADGIRHLVALRGDPPSGEASYR
PHPGGYAYAADLVAGLRQFADLDISVAAYPDVHPEAPSAAFDLDNLKRKFDAGANRAITQ
FFFDVDRFLRFRDACDRAGIRGPLVPGLLPIAKFSQLLGFAARCGTPVPAWLHQRFEGLD
EDPETRQLIAASVAIELVGRLRRHGVDEFHFYTLNRAELTYAICYALGLRPRAAEASA
>A0A7C3BTE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTNLEKVLESGMFAVTAEAGPPKGTGAAVIQRKGELLRYCCDAINVTDNQTAIVRMS
SLASCVLLKQGGVDPVLQIVCRDRNRLAIQSDVLGAAAVGIGNILCLSGDHQKFGNHPNT
KNVFDIDSIHLIQTLKMMRDEKKFLCGEDISGEVPLFIGAAANPYADPFEFRVVRLAKKV
KAGADFIQTQAVYDMDKFAKWMEMITDRGLEKQVHILAGVIPIKSAGMARYMRDYVPGVS
VPDEVVTRMEEAKNPKEEGARIVIDIIEQLKEIPGVHGIHIMAVGWEDIVPEIVEKAGLL
PRPVL
>A0A2N3A5L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-11|TrEMBL
MKLTEHIARRQGSTLFSFELLPPLKGENFEGISQAIDPLIEFNPISIDVTYHREEIVYKE
RGNGLLERRTVRKRPGTVGISAAIKFKYNIDVVPHIICGGFTREETENALIDLYFLGIDN
ILLIRGDNPAGEKVFRPEPEGNHYALDLVNQAVNMNRGIYLEEGIINANPTGFCIGVAGY
PEKHAEAPNMAADIAHLKAKIDAGAEYIVTQMFFDNAAFFRFEKACRAAGITVPVIPGIK
PLSTFSQLSTLPKTFSIDLPESLVLEAEKCSKKDQIRDLGVEWAIAQSKELIKHGVPVLH
FYTMGKSDNIQRIAKAVF
>D6M2D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. (strain SPB074)|TrEMBL
MAFGTASTWTSEHPTVAEVLASGKRSFSFEFWAPKTPKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRTGTVRATQAIAENTTLVPVAHLTAVEHSVAELRHMIGQYADGGVRNILAVR
GDPPGDPLGDWVPRADGLTYAAELVRLIKESGNFCVGVAAFPDMHPRSENWDSDVRHFTE
KCRAGADYAITQMFFDPASYLRLRDRLAAAGCETPVIPEVMPVTSVRQLERLSRLSNAVF
PETVKDRMLAAKDDPAAVRSLGIEFATEFCARLLAEDVPGLHFITLNNSTATLEIHENLG
LPHHRP
>A0A2E8S9M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSGQLEEQSKLERVLRSGQLAVTAEINSPDSSLPESVHRNALVLGSLCDGINATDASGAN
VHLSSIAVSAILQKAGYEPVMQISCRDRNRIAMQGDLLGAAALNIKNVLCLTGDGVQTGD
HPEAKSVFDMDSINLLKMTRTMAHEGRFLSGRKLESKPKFFLGAAANPFVPPFDFRPLRL
KKKIDAGAKFIQTQYCFDVPRLKTYMDAVNDMGLSEKAFILIGVGPLKSAKSAQWIRSNV
PGVVIPDAIIRRLKQAKDQAAEGKKICLEIVQQAIEMPGVKGIHIMSYGQEELVPEIIAE
SGILDNRNNNI
>A0A0C5EUU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MRSN12121|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLSQYQAAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVDRVRKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1W9I1T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium SG_bin7|TrEMBL
MTIVDNQDKKITDFLKDYKFTLSAEVIPPRNGAEQANILTQIDLLVSHGAQFLSVTKGAG
GSLRGGSLPIAHAIKDRFKVPSIAHFTCRDLTPQDVENQLIDHHYFGIRNILALRGDPPT
GQKEWKAREGSYSYAYQLIQQIKKLNDGQFLERPDGPKAKSREKLDFSIGCAVYPEHPIE
KERIDFFRLKVEHGAEYAISQMLFDSDAYSRFLELTAKAKVTIPVLPGTRIIKTKEAGER
MAKRFEINLPKSISSTLGTDEDQKRDPKGVMEKSLEAFIRFIEKLKSIGAPGVHVFVLSD
TEISCLLLQRLKKI
>A0A495YID8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Nafp2/4-1b|TrEMBL
MKSFELSFEFFPPKTADGVEKLRATRAQLMPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSDMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTDLCRRLIDAGVPGLHFYTLNAASATRTICERLAG
>A0A323UA92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas palustris|TrEMBL
MSDLPQQLPAISFEFFPPKSEEMERNLWQAISRLAPLHPSFVSVTYGAGGSTRERTHATI
ARILQETDLTPAAHLTCVDAPCADVDEVVTRYHDIGVRHIVALRGDPTTGLGGTYTPHPQ
GYRSSADLVASIKRRYPDIDVTVSAYPEKHPESTGFDADLDILKAKVDAGATRAITQFFF
DNDLYFRYLDRVRARGIDIPIVPGILPVQNFKQAAGFAARAGASVPDWLAKQFEGLDDDP
DTRKLVAATVAAGQVHKLAKHGVGNFHFYTMNRADLVFAISHLLGFRPQAARQAA
>A0A3C0JPY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIKDILNNIRTISCEFFPPRTEEGIPDVFSAAGRLKAYKPDFVSVTYGAGGSTRAFTER
ITSELKEQSELEVMAHLTCVGQSKEEIHSVLERLDQTGIENIIALRGDPPRGETDFVPTP
GGFQHATELIEHIQGNFQMGVAAACYPEGHTESPNLNSDLEYVKQKVDKGAEFLITQLFF
DNNDFFEFLNRAKSAGIDVPIIPGLLPILSAPQIRRFSTMCGASIPADLDRQLDKFADDD
QGARALGIEHATKQVEELWDSGVPGIHFYVLNRSYSVSKILDNLSLQGRNGLG
>A0A3C0Z051|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSNASRQVVDGSCRRVVLNQLASVLKSGKFAVTTELNPPKGTNLGPMLRRAAPLKGLVDA
FNVTDSASSRMTMAPVAAAHMLLDEGLEPILQITCRDKNRIAIQADLLGASALGITNLLC
MRGDNPQAGDHPDATPVFDIETIELLEAIGSLRSGTDMMGAQLRGAPELHVGAVCNPGSP
DMEGELKRMEEKIAAGAEFFQTQAVYDSKAFDAFMSEAKAFDIPVLAGMILLKSGDMARN
LNANLWGVSVPDGLIRELDDAEDKGAKCIEIAARTINEISSMCHGVHIMAIGWESRIPKI
LEGAGLSPG
>A0A349AMZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKKITDIFSEKEKTFSFEFFPPKTEVGMKKLYDIAETFAALKPDWFSVTYGAXSYSGYCG
QVPETL
>A0A1T1QQ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. vitiscarnosae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A3N5YT93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKPDSRLAKKIEGKDFIITAEYLPSSGTAASAIEASLGFLRDGPVAVNVADNHYGVAVSS
FAASVGLGRYGIEPVYQVVTRDRNRIALQSDLLGAAFLGIKNVLCLSGYHQALVGCPDSA
NVFDIDSIQLIAAVRKMNDEGLLLDGSKIDGPFSMLIGAAANPSLRPLELNVIRIKKKVK
AGADFIQTQAVFDMEAFKQWLDALKSAGITDRVAILAGVMPLTGAAEAKKLNETFTDFTI
PSSVIDRLEKAGSEEAQKKEGIAICVEIIKQMKSMPGLRGVHILSGGNEAVVPQIISAAA
>A0A1F9A3I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_43_22|TrEMBL
MKIESQLKNVLAAGRFAVTAECGPPKGADPEAVIKKGRILKGYVDSVNVTDNQTGVVRLS
SLAACVLLLQEGLDPVLQMVVRDRNRIALQSDLLGASTLGIRNVLCLSGDHQSFGNQTQA
IGVFDLDSIQLIQTVRRMRDEGQIIGGEAVSPPPYLFIGAAANPFADPFFYRVIRLAKKV
KAGTEFIQTQCIYNLDRFKEWMSQVRDRGLHEKVYILGGITPLKSAKMAEYIKNQVAGMD
IPEPLIRRMKSVPAKGQRKEGIKISIETIQALKEMEGVHGVHIMAIEWEEAVPQVVEQAG
LMPRPTV
>J6DSK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. CCGE 510|TrEMBL
MALNNARGRNIGISFEFFPPKSEEMEGQLWQTVSELQDWDPDFVSVTYGAGGTTKAPTLT
AVTRFLSQTPLATASHLTCVGATKEETHQVIDTFRKAGVTHFVALRGDAPGGAGAPYQPH
PGGYANAAELVAGLREIGDFEISVSAYPEKHPESRDTAADVEMLKRKADNGADRALTQFF
FDNDNFERYLERVRAAGISIPIVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDDR
PEERAKVAADVAAEQIEDLVRRGIRDFHLYTMNRSPLVSAVLDNLGFSRRAAKSAGAAA
>A0A3A0ET09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTPPDFRPNLFAFAPGDVAVSFEFFPPKTAAMEQTLWEAVRALAPLHPRFVSVTYGAGGS
TRERTHNTVVRILQETALIPAAHLTCVAASRDEVDEVARRYWAAGVRHVVALRGDPPEGD
TRFTPHPQGYENAAALVAGLKRIGDFDISVACYPERHVDSADWQAELDNLKRKVDNGASR
AITQFFFDPDLYFRLVERATAAGIHVPIVPGIMPVTNFKGITSFAARCGASVPKWLAELF
QGLDDHPATRQLVAAAVSAELCRRLYDGGVKEFHFYTLNRAELTYAICHTLGLRPEEKQT
>A0A3A0EU91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSRAYYDPAAEYAPLPGHSSRGRFERVLRSGKFAVTAELNPPDSADPRDVYERALVLAEV
CDAINATDASGAHTHMSSVAVCSLLSRAGYAVVMQISCRDRNRIAIQGDVLGAAAIGVAN
VLCLTGDGVEVGDQPEAKPVFDLDSISLLQTIRAMRDESRLLSGRKLTSPPRLFLGAAAN
PFAPPLDFRPLRLAKKIAAGAQFVQTQYCFDLATFRAFMQRVRDLGLDQQCFILAGVGPL
VSAKAAKWMRANVPGIHIPDAIIERLEGAADQRREGKNICIELIQEIRAIPGVAGVHVMA
YRQEELVSEIIQQSGVLQGRRPVNRDRRKTITQETQA
>A0A249KU41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Planktophila vernalis|TrEMBL
MSQMREKLENTNEVVFTAEFPSLDGGGMAKVVKNAARLAPWFVGVNATDNPAAHAHASNT
ASAIAMKMHGIEPIMQIVCRDKNRLAIQADMMGAALHGIENISLLTGDDVTAGDEPETRR
VFDIDSTQAINIARIITTGKYLSGRKIDPAPDFYISAVENPAAPPFDYRIERALKKYRAG
AKYLQLQICYHPERLEKFCAGVAKIAPDLKLIPTIVLVKSAKPMSFMHDKVPGIDIPQDT
INRVSSAADQAEEAYKLTVELAKHAMTLPSVRGLHVTDFRHDDSLDRFMYDLGQKPRN
>A0A848SKV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp|TrEMBL
MSPTMNQMREAQRALETPLFSGLPGDIDVSFEFFPPKTEKMGETLWQSVETLRPLGPRFA
SVT
>A0A1V2AAY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Domibacillus epiphyticus|TrEMBL
MTLLNRLKTDVLTADGAMGTLLYSYGIDFCYEELNTEKPEIIEKIHKDYIDAGADIIQTN
TYGANSIKLARYGMENRTNELNKAAVEIAKKAAAPGGQFVLGTIGGIRGIRKSSATMNDI
LSSVREQAESLLAGNPDGLLLETYYDFEELSSSIQLLREMSDVPVIAQVSMHEPGVLQNG
LSLNEALHRLEGIGADIVGVNCRLGPYHTIQAFEDVTLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGRAAVHLRNEGVRLIGGCCGTTPKHIEAAKKRLAGLPPLTEKNVKIKKPIV
IQEASPMTDVSICEKAKTERTVIVELDTPKTLLTEKFIEGAKKLYDAGVDAVTMADNSLA
SPRVSNMAMGATLKMKHDVRSLVHITCRDRNLIGLQSHLMGLDSLGLHDVLAITGDPTKV
GDFPGATSVYDVSSLELIQLIKQLNEGISFSGKPLKKKANFSVAAAFNPNVRVLDRAVKR
MEKKIECGADYFITQPVFTKEKIIEVHEATKHLPTPVFIGIMPLTTMRNAEFLHNEVPGI
KLSDETLERMRACGDDKESSAKEGVQIAKELLDTAAELFNGLYIITPFLRHDMSTELIHY
INELDAQKESGALHDYSSN
>A0A143WMW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tremblaya princeps|TrEMBL
MPGLSFEFFAPRSHAGSIRLMCAQQVLSRFVPRFVSVTRSASIGQQAHIETIASTLRVFP
RTAPHVLFCQCPRALARELRAYELLGIRHLVLLRGDNGIAPGSLGAPELVSLVRRSYGEA
FYIDVAAYPDGHPMASTVFDDVRALARKVRCGANSAITQCFYNPDAYYRLQDELQRLGVS
LPVTPGIMPGLSHAYMARFILPSGVDVPAWILKRLEALRYCSASVLEFGTDVALSLCESL
AARGASDFHLYTMNDHRAVWRVCEHVLGTAATCHRRGALCAAPCA
>A0A1G3VIF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophus sp. RIFOXYC2_FULL_54_9|TrEMBL
MKNEKPFHDQLKSGEFIVTAEYLPGAETGGTAIEATLQALVEVPSAVNVADNPFGVAMSS
LAASVLLARAGIEPVYQVVTRDRNRIAIQSDLLGAVALGLRNILCLSGYHQTLTDNPESA
NVYDLDSTQLVAIVTKMRDRGELLNGTRIRGPFPVVAGAVANPCLKPVDLGILRLTQKVE
AGADFIQTHAVFDVDQFGVWLDAAKQAGITGKTAILAGVFPLEGVEEAEALAKKYTEFQI
PASVIERLKSAGDPEAQKKEGLAICVETIDKLKSMSGLRGIHLLSGGKEAALPAILSAAG
LTGKR
>A0A432HB00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR324 cluster bacterium|TrEMBL
MHLIELYKKKDFVFSIEIFPPKTAKGMEKLKTTLEAFKSCTPDYFSVTYGAGGTSRENTH
ELAAHIHHDLDVPAMAHLTCVAHTVEEIDVVLSNLKNSEITNVMALRGDPTAGTKHFVQP
KGGYHYASELITAIREHSDFGIGAAGYPEGHLENPDKDDDRKHLHEKIAAGAEFIVTQFF
LENTHFLRWRDQLRREGASVPLVAGILPPANWKATKHMSEMCGVSIPEDLAQALIKNETD
PEASREIGFDHVENQFEELLQEGVEGVHLYALNRLSTVERLGPILKDASGTISTPHL
>A0A1Y4WLG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor sp. An100|TrEMBL
MKLHELFQTGKTVFSCEVFPPKKTSPVDSIYKTLDGLKDIQPDFISVTFGAGGSQVNQTT
REIAAIIQNQYHIPAMAHLTCVAAGREEVDGLLAGLKADGVENVLALRGDVNPSVPPKTD
FLHANELVSYIRSTSDFGVSAACYPEGHLESPDLVSDIRYLKAKVDAGAQHLVSQLFFDN
EDFFRFLERCRIAGITVPIEAGIMPVLSASSIQRMVSLCGASLPRKLTRLLGRYGDHPQA
LREAGIAYAIDQISDLIAGGVDGIHLYTMNNPDVARQIAGSLSSIRSL
>A0A4Q5TAT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium|TrEMBL
MSPPLIHPNWSRPATSAIDGYSIEITAKDADALRAVAPRIPPATPIAIAFLPGESLDARV
RAAQTIRALGFEPMPHFSARRIGSGAEFEDYLAAVVEQAGVQRCFVVAGDPSTPAGPFAD
SASLIATGAFERSGIRAIGVGGHPDGHPNMTQAECFAVLDGKCHEIARRGMAPLIVTQFG
FDADAVVRWLSELRSRGIDAPVRLGVPGPAGIKTLMRFAALCGVGASTAVLRKYGLSLAN
LIGSAGPDRFVAILEAALTPDHGPVRLHFYPFGGLARTLDWIDGYARATGLDPSA
>A0A1V5FUM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division BRC1 bacterium ADurb.BinA364|TrEMBL
MKISRLLAQPGPTFSFEFFPPKDEAGANQLLETIQTLGALSPSFVSVTYGAGGSTRRRTI
DLVKQIARERRIETMAHLTCVGASREEIAATLDELAAAGLDNVLALRGDPPKGESEFRPP
AGGFAHASDLAAFIRERYSFCLGGACYPEGHPECRSIEQNILHLKIKIDCGVEFLITQLF
FVNEEFFRFREKAALAGINAPIIAGLMPIGSLAQIQRIGSLCGAKIPASLVQAIENAASP
EEARAIGIEYSTVQCAELLREGVDGIHFYTLNRSTATRAIWARLTGGTPPEWTE
>N9PCK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 64.7|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAADLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVEKVQAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A099XYT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. Hel1_85|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPKKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYLD
KGNGLLDKRITRMRPGTVGICASIMHKYKVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKDEPYFKPVKGGNAFATELVDQIASLNRGKYLHDDVQVEHHSDFCIGVAGY
PEKHMEAPSLVSDLRRLKEKVDAGADYVVTQMFFDNNKYFEFVKAAREIGINVPIIPGIK
PLAVQRHLQILPQVFKIDLPQDLIDAVDGCKDNKAVRQVGVEFAIQQSKELLAAGVPVLH
YYSMGKSDNVQAIASELF
>A0A291GSQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium vulturis|TrEMBL
MTQSPLPGPVPHAAAQGREVQFEVIPLRGILDEVSTHLPPGARVTVTASPALGLPATLEL
AGALAQRGFPAIPHLAARMLHGAGEVEEVLARLTETGVTEAFVIAGDAPHPAGDLPGALE
LLEAIGASGSGITVGVGVHPEGHPFVSESEAMRLLRAKAEHASYAVTQMCFEAAPLLAWV
RRLREGGLLLPVRPGIAVPAGTARLLRIGTRIGVGRSLRMLSGEDAGVRRLLGPGHWSPG
PLLEELERARAAQPELGLHGPHLFTFNAVRVARECAAGL
>A0A0G3WNW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pyrrocinia|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTDLCRRLVDAGVPGLHFYTLNAATATRTICERLAM
>A0A2U9U522|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. XJLW|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTEEMEKILWGSIERLAPLQPSFVSVTYGAGGSTR
ERTHNTVARMVRETGLKPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPAEGVGH
AYRPHPGGYASTAELVEGIKRIGDFKVSVSAYPEKHPEAASLDADIEALKAKVDAGADQA
ITQFFFENEVFLRYLEKVRAAGITIPILPGILPVQNFKQAANFARRTGASVPYWLAARFE
GLEDDVETRRLVAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AAKAAA
>A0A350KXE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp|TrEMBL
MSPTMDQMREAQRALEAPLFSGLPGDIDVSFEFFPPKNAAMNETLWQSVETLAPLGPRFA
SVTYGAGGSTRERTHQQVVRIQNEARIPAAAHLTCVEATREEVDEVARHYWDEGIRHIVA
LRGDAPDGQSQYAPHPGGYANAVELIAGLKRVADFEISVAAYPEVHPDSPDRQADLDNLK
AKFDAGATRAITQFFFDPQCFFDFRDRAAAAGIDGEIVPGIMPVLSFAAVRRMSGLCGTA
IPPWMEGLFDGLDDRPAARQLVSATIAAELVRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRAKAGR
>A0A851VRZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Copsychus sechellarum|TrEMBL
MVNETQHACSGSSSSRSDGGSSSGSESSKDNSRCSTPVLDPDRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRSYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWREDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDELERVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6N3I8I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp. 86|TrEMBL
MHIGDGIRAAKKPFFSLEFFPPSDEKILPGFFETVEKLRALAPLFVSVTYGAGGGKQRNT
LAVTAELARRGLNTMAHLTCVGAEPESISAYLAELRAVGVDNVLALRGDPPVGQETDWSK
GYFRHASDLVAFARRQQPYMGIGVAAYPAPHPESNSIALDRLHTADKMRSGADFAVTQLF
FDAREYADLLEHLRGMGIHTPVIPGILPIQSFDSLRRVLSLCGANIPGKLYLDLESANAK
GGAEAVREVGLEFAVRQIRFLLENGAPGIHLYTLNKASMCLRLAEESGLLQA
>A0A6M1YC03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenzhouxiangella sp. XN24|TrEMBL
MPDPGVFALNRPPINLSFEFFPPRDAKLEARLWQTVERLAPLAPKFVSVTYGADGSTRER
THDIVTRIHADTGLVSAPHLTCVGASRDEVLEVARRYWDAGIRHIVALRGDPPKGSETYV
PHPEGFAYAADLVAGLRTIGDFEISVAAYPETHPEAPSPAADLDNLKRKIDAGATRAITQ
FFFDPAAFLRFRDAAAATGITVPIVPGILPITRFPQITKFAAACGASIPPWLQERFAGLE
EDPDTRAMIAASVAIDMVETLRRHGVVDFHFYTLNRAELVYAICHCLLHSPAPQVAYA
>A0A847MQ54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Intrasporangiaceae bacterium|TrEMBL
MTAKDVSSLAETAQLVPPGTRVNITFLGNEDHPMRVAAARAVREVGLVPVPHLAARRLTS
EAELSELLDRLAEAGASEQVCTIGGDPATAAGPFTDSLSVIRSGLLTSHGVRGVSIAGYP
DGHPDIPSEVLWRHLTDKVAALDEQGLEATIITQFSFDHEAVRSWIREVRERGITAPIRV
GTPGPVNAKRLLGFARRFGIGTNTLIIRKYGFSLTNLMGTAGPDRFVSDLAADLSDLPSA
GAVGLHFYTFGGLVPTSRWAMDFAATSERSSRSTATNR
>A0A0N7KUL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asaia bogorensis NBRC 16594|TrEMBL
MSRIAIELIPRDTQSLTEDLATVRQIAPDVTTINLPDLLRLPLRSWEGAALAQGQGYAAI
PHIRAIDIDPDAPLPCAEQEGLREILVIAGDPPPDSTHRIWPNSSADIITRYRREAPHLT
VYAAFDPYRRAPWQELETIQQKRDAGAAGFFTQPLFDRRLFDLCASWLENDQVFWGLSPV
IGPKSRAYWERVNHVVFPSDFEPRLDANIAFARTILEAVHARGESAYLMPLRVPLADYLT
PLRDLLTF
>A0A2D9K9X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium|TrEMBL
MVSYAQGVDALNQSLSELRDIDVSFEFFPPKTESMEKTLWKSVERLAPLNPSYMSVTYGA
NSGERDRTHDIVKRIQQQTGVTAAPHLTCVDATKDELKQIAKDYWDSGIRRIVALRGDLP
QGVEKTDMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDASVYLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGYLHKMLEGL
D
>A0A2B7ZRC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emmonsia crescens|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFVDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCEDQDDPKLLMQHLKEKVDAGGTF
IITQMFYDVDNFLAWVKKCRENGIVVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEAL
EPVKNDDAAVRNLGKSLVANMCKKMLAAGIHHLHFYTMNLQQATKMVLDELGLVPSHETP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSLKELSEIFVRFLDGNLDRLPWSEGAVTEETEIIKPDLLE
LNQRGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNP
DLTYYCVNKNGELKTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHPATSPSRRLIQQVMDSWYLVNIVNNDFHKTHDIFNLFKDLRVKNFDTEVEPIAPAAE
PVDNTQQNGQPQKYVNGSSTEATESEQKLNSN
>W4PHS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides pyogenes DSM 20611 = JCM 6294|TrEMBL
MRVIDLIHNNTKTAFSFEILPPLKGTGIEKLYEDIDTLREFDPKYINITTHRSEYVYKDL
GNGLYQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFSREETEYVLLDLQFLNITDL
LVLRGDKAKHESSFTPEKDGYYHAIELQEQINRFNQGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMEADLYWLKKKMEAGAEYAVTQLFYDNKKYFDFVKQAKAAGIHIPIIPGIKP
FRRTSQLSMIPKTFKVDLPEDLVKEVLKCKNESEVEQIGIEWSVNQCKELMSFGVPSIHF
YSIGAVESIKEVAKLIY
>A0A3D3V3H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudothermotoga sp|TrEMBL
MKLIDKLKEGPILSIEVLPPNRGHSVEEIFRTIDQLMEFPISFINVTRHAPELAYIESDG
QIVRVTKVKRPGTVGLSAALMHRYGIDVVPHVICYGMDKYQIEDLLIDLHLIGISNVFVV
RGEYENPLSGQQDRSSYKHAVELVQHIANLNRGVYLYPTEGSEPTDFCIGVAGYPEKHFE
APNMEEDLMNLKRKVEAGAHYIVTQMVFDVEIYRRFVQMARNFGIHVPIIPGVKPVVNLK
SIYSIPKKFFVTIPASFVSQMHQARSSEEEFIIGVRFAAKLAEDLLVAGAPGIHVFTMGR
AKATKAMLQLLYSRQA
>A0A426HH03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas sp. SGD-10|TrEMBL
MTPISFEFYPPKTDEQRAQLDRAASRLAAWGPEYVSCTFGAGGSTLSYTADTVRHLNQHH
GFEAAPHLSCVGGSREEIRELLRRYRELGCRRIVALRGDLPSGMGHPGDLRYAAELVQLI
RAEHGDHFRIEVAAYPETHPQAEDALADLRHFKAKVEAGADAAITQYFYNADAYFRFVDD
ARRLGVEVPIVPGIMPISNFTQLKRFSEACGAEIPRWIARRMQAYGDDLAAVREFGADVV
ADLCRRLVAGGAPALHFYTLNLARPTETVLQRLA
>A0A373B953|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. SWAC57|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDQDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPIINASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A2R3QMT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mendocina|TrEMBL
MSNPCSSSTDFIPYTLEVTGKGIREVEQARAAIPAGTPINIAFLGNEDHAQRIHAAKVIR
ACCAEPVPIISSRRLRSEEDRDELIGALVEQAAPRRFMFVGGDPAIPAGPYHDSLALLAS
GVLERHGIDQVVITGYPEGHPKIDSGELMRALKWKLDFLREAGCAVEITTQFGFDAEAVV
RWIAQLRQQGIETPIRIGVPGPADVGKLLRFARQFGVATSASILRLYGLSMTNLMQRVGA
ERYWDQLQAGLGGRRLGSIGWHLYPFGGIEDGVTWINARLSAAASLQVSSR
>A0A4R6UVU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Permianibacter aggregans|TrEMBL
MGLTAARLLETLNRQWEKVEDRLNVSFEFFPPNSPEMADTLWQSVVKLAKFKPQFVSVTY
GANRSTRDRTHAVIERLVQETDLTPVPHLTCIDASREEIADIVSRYRQLGVNHIVALRGD
LPASATQTGGDFQYASDLVAFLRQQGVEKISVAAYPEVHPEARSARHDLDNLKRKVDAGA
TDIITQFFFDNCAFLRFRDRCRSAGIELPITPGILPVSNYRQVERFASGCGTRVPSWMGH
LYEGLDDDPETRRLIGASLALEQVKLLINEGVADFHFYTLNRAELSYAICHALRLVGLPG
RHAAPQLASV
>R5YAA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:144|TrEMBL
MNVAEIIKNSSRTAFSFEVLPPLKGNSIDKVFDTIDALREFDPKYINITSHRSEFIYKAA
DNGLYQRVSEKSRPGSVAVAAAIQYKYRIPAVPHLICSGFTKSETEYALIDLNFLGITDL
LILRGDKAKHEARFSPSPEGHAHAIDLQQQVNRFNEGYFLDGSHMTLSSPFSYGVAGYPE
KHDEAPNLETDLRHLKAKVDAGASYIVTQMFFDNAKYFAFVERCRAEGITVPIVPGLKPI
TSANQLTVLPKVFHVDLPEPLARELAACRDDAAAREVGVEWCTTQARELKDRGVPSIHFY
SLMATESVRRVARAVY
>A0A2A8D143|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Longibacter salinarum|TrEMBL
MKVIEHLERANNPLISYEIIPPKRGGSAEQMLGVVEELMPYEPPFIDVTSHSAEVSYKQM
PDGAWQRCVKRKRPGTLGLCAAIEARFGIDTVPHLLCRGFTREETEDALIELNYLGIDNV
LAIRGDDKGYDKQIPNERSQNEYAVDLVRQVRAMNHGEYLEDLMEAAPTDFCIGVGGYPE
KHFEAPNLAWDIMHLKKKVDAGAHYVVTQMFFDNEKYFDFVDRCREVGIDVPIIPGIKII
TNKRHLRSLPRYFHTEIPEDLAAEVEAADPEHVDDVGVEWALRQTEELMSAGVPCAHFYI
MSSAKTVKRIVEPLREMA
>A0A255ZMQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax sp. TH121|TrEMBL
MFANDRIPLSLEFFPPKTPEGAEKLRGVRQQLYALQPEFCSVTFGAGGSTQEGTFKAVSE
ILAEGVSAASHFSCIGATKATVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDL
VAFIRAETGDDFHIEVAAYPEVHPQAKSPASDLQAFATKVKAGANSAITQYFYNSDAYFR
FVEEVDALGLDVPVVPGIMPITSSTQLLRFSDACGAEIPRWIRLRLQSYGDDVASIKAFG
LEVVTDLCEQLRAGGAPALHFYTMNQSAATLALCKNLGLAA
>A0A7G3FR51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivirga sp. XM-24bin3|TrEMBL
MKVTEHIKNAEGKTLFSFEILPPVKGESVQSIFDAIDPLMEFKPPFIDVTYHREEYMYKK
RENGLLEKVTTRKRPGTVGICAAILNKYGIDPVPHIICGGFNKEETENALIDLDFLGVEN
ILVLRGDAIKSEGRFEPDPDGHSYATELMDQVNELNQGIYLHEEVTRNPTNFSIGVAGYP
EKHFEAPSLKSDMKYLKQKVEKGADYIVTQMFFDNKKYFDFVDKCRSNGIDVPIIPGLKP
ITTLKHMNILPSIFHVDLPDDLVDALDKCKDNAGAREVGIEWAIQQSKELMEAGVPVLHY
YTMSKSQVVRRIAEALF
>A0A1V5BGN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelotomaculum sp. PtaU1.Bin035|TrEMBL
MKTSEIFKIKKVLSLEIFPPRRTASIDIIYNTLDELRGLNPDFISVTYGAGGSENNTATL
EIASAIKNNYGIESVAHLPCINLTKNEVLNILEGLKQAGVENILALRGDVNPAFAPKQDF
RYAGDLVSFIKENGDFNIIGACYPEGHSECPSLVDDIRNLKIKVDAGTDQLITQLFFDNS
YFYSFLERASIVGINVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFITMMEKYENNPVAM
RDAGIAYAVDQIVDLMAQGVDGIHLYTMNNAYIAQKIYAAISTLLTA
>A0A6H1L528|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. RPA4-2|TrEMBL
MAITCSPKFGLLRTLNHVAAARRSGHRVVPHLAARMVEERRDLRHFVRRITDLGVDELFV
IGGDGEEPAGRFKEATEILQELGEFDHGVSKIGIGCYPEGHPKISEDVLFDALLRKQQYA
DYMVSQLCFDASAMAGWLRFARDRGVTLPLRIGVAAPLQVRKLVELSVKIGVGQSVRFLS
KQHGLVGNLLLGRAYEPMDLLLAIQKEISFTDLSVEGLHLFSFNQVDTTLDWLSRTSGVE
EAG
>A0A4Q4JI96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporolactobacillus sp. THM7-7|TrEMBL
MRTPLLEELKKRILIGDGAMGTLLYSYGIDRCFEELNVSHAEEILHVHKAYINAGSDVIQ
TNTYGANAIKLARYGLEEEVRHFNEAAVRIARQAAQPSTYVFGTVGGIRGFGKQSAELDE
IRRGFEEQVSCLLENGVDGLLLETYYDVDELRSVLKLARSATDLPIIAHVSMQEPGVLLN
GMTLADVLSELEELGADIVGTNCRLGPFHMIQALEGIPLPKHAFLSAYPNGSLPDYRDGK
LYYKTEPEYFKKYAVDFRNEGVRLLGGCCGTTPVQIQAFKQGIAELAPLEKKTVTEHTET
IVIEREDSHSETPLFEKAINGRSVFVEFDTPRHLKTSSFFKGVKAIQEAGADAVTMADNS
LASPRISNTAIGRLIKEKFSIPPLVHLTCRDRNLIGLQSHLMGLDVLGLHDLLIVTGDPT
KIGDFPGATSVYDLSSMQLIELVKKFNRGISYSGKTLKKATHFRVAAAFNPNVRNLDRAV
QRLKRKEDSGADYFISQPVFDKERILEISEATHSVSAPIYLGIMPLISSRNAEFLHNEVP
GIRIPDDVRVRMAQAKSKEKARRTGVAIAKEMIDIAMEHFRGIYLITPMGHYNMTVELVQ
YVKEKERTLSNKTIGAANNLS
>A0A4Q6DC06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxellaceae bacterium|TrEMBL
MNDIRLSFEFFPAKSEQGRDKLIQVQQELSAFKPEFFSVTYGAGGSTREHTKGIVQLIKQ
AGQDVAPHISFGGDTPEELLGLLNEYKAFGINRLVALRGDRPSGMGGGLHMVYANELVAF
IRQHFGTYFHIEVAAYPEIHPESQSFNSDIQFLKGKFDAGANSAITQYFYNPDAYFYFVE
QCRTHGIVGDIVPGIMPITNYKNLSRFSDSCGAEIPRWLR
>A0A2T7TMZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Bz4|TrEMBL
MSFAHSPPQSYPALSYELFPPRSASAEEALWRTIRALEDTRPDFVSVTYGASGSNRDTAI
GLLMRLLDETTLKPLAHLTCVGNSRDYLMELIDELISRGVRGILALRGDRPQDMSLSAGE
LHYASELVELIRRVERQLTAHLCAGKVAVGVAAYSTKHPESPSLEHDIEVLLAKQSAGAD
FAITQVYFAPDHYRRLLRTARRAGVEIPIIPGVIPFTSVQRLERLSELAGIEVDVTLRDR
LMNADDDAARRRIGVQATVDLAHAALDDGAPGLHIYTFNEHGAALDVLDRLELSRPPAPG
LSRSA
>A0A558I3B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio tasmaniensis|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVKLLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A4V6JIZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia rubidaea|TrEMBL
MPGILPVSNFKQLQRFAAMTNVRVPSWMTSMFAGLDDDPETRKMVGANIAMDMVKILSRE
GVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A291QS20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga caeni|TrEMBL
MKVIEHIEQAKDTLISFEILPPLKGKSIESIYDHLDPLMEFNPAFINVTYHRSEHMFKKK
LDGSFEKVEIRKRPGTVGICAAIMNHYNVDAVPHLICGGFTKEETENALIDLAFLGVDNV
LVLRGDAPKNETFFEPEPNGHRYAIDLLHQVMHMNNGMYLEEDLQNGVKTKFCIGVAGYP
EKHFEAPNLQSDLQYLKQKVDSGADYVVTQMFFDNQKYFDYVKKCREIGINVPIIPGLKP
LTTKKQLSVIPRTFQVDIPTEFSNEILKCKTDKEVEQVGTEWLIQQSKELKAFGVPVLHY
YTLGKPLVVRKVMEAIQ
>A0A354H6G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxellaceae bacterium|TrEMBL
MTTPFSFEFFPTKTDDGQTKLLATFDELNALKPQYFSVTYGAGGSTRERTLGIVKALSEK
SDTPITPHLSCIGDDKAKIGELLDYYKSLGINRLVALRGDLPSGMVGLGELPFAVDLVKY
IREHSGDYFRIKVAAYPEMHPQAKSFDADIQNLLNKYHAGATEAITQFFYNADSYLYLRD
ALAKKGVTQDEFPIIAGIMPITNASNLIRFADGCGADIPRFIRKQLADYGDDKKAIRQFG
FEVMVNLCERLIAEGVPSMHFYSMNQVSPNKQLIEALGLV
>A0A2P5LL70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacter sp|TrEMBL
MESQKKFSRSFSFEFYPPKSEEGAASLINVHNELAQLKPDYFSVTFGAGGSTRDKTFESV
VAIQQKGIPAAPHLSCVASSRDSIREILKNYQTQGVNKIVALRGDLPSGMMSLGELRHAN
ELVALIRQESGEYFQIHVAAYPEVHPQAANAAQDLKHFKLKVEAGADAAITQYFYSPEAY
FHFIEACEKASIDIPIVPGIMPITNYSQLFRFSEMCGADIPRWLRKRLEGFGDDRQSIQA
FGIDVVSELCQRLLDNGAPGLHFYTMNQSAPTLAIWKNLQL
>A0A3D3K9Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxellaceae bacterium|TrEMBL
MTTPFSFEFFPTKTDDGQTKLLTTFDELNALKPQYFSVTYGAGGSTRERTLGIVKALSER
SDTPITPHLSCIGDDKAKIGELLDYYKSLGINRLVALRGDLPSGMVGLGELPFAVDLVKY
IREHSGDYFRIKVAAYPEMHPQAKSFDADIQNLLNKYRAGATEAITQFFYNADSYLYLRD
ALAKKGVTQDQFPIIAGIMPITNASNLIRFADGCGADIPRFIRKQLADYGDDKKAIRQFG
FEMMVNLCERLIAEGVPSMHFYSMNQVSPNKQLIEALGLV
>V6HA48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira inadai serovar Lyme str. 10|TrEMBL
MKKILEIYTNAKEPVYSFEFFPPKTMEGEAKLYETVTELSRVNPGYITVTYGAGGSTRDK
TIRLTSDLARKFNLAAAAHFTCVGGNKEEIHTILKEIESSGIRNLMALRGDPPKGEGAFR
KVEGGFEHASELISFIKSEGFDFCMGGACYPEKHPQSTDLDKDVDNLKKKVDAGADYLVS
QLFFKNEIFESFLNLVRKKGIRVPVVPGIMPITSFSQIERFRSMAACEFPEKLLVDLEEV
QNRPEEFYRRSLNFSVEQCRELIEMGSPGIHLYTLNQSHASYDIVRELRGEGK
>A0A370SHJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas jessenii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKGDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A087AIT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium gallicum DSM 20093 = LMG 11596|TrEMBL
MHHPMHTRFDYEKRNQHETRPHFTLEVFPPKRNASVGTIYDTLDGLTGLKPDFISVTYGT
GLSADRTATARIAHTIHHEYGINAVAHLTAQYLTADDVDEALAMFDDAHVSGILALRGDR
NPDREPVNVFTHASDLTAYIRQRRPDLEILGACYPEKHPQASTLQEDVDNLKRKVDAGAT
RLISQLFYDNDDYYRFLDLARDAGITVPIEAGIMPVTNAKSVRRMTSMCASRVPAPVEQM
LTRWSDDPATLQQAGIIYASQQIADLVAHGVDGIHLYTMNRPAVARRIWTNVQDLFTADQ
QPQA
>C6C5A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Musicola paradisiaca (strain Ech703)|TrEMBL
MSFFHANHQEALNQNLAELQGRINVSFEFFPPRTREMEETLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKAIKERTGLEAAPHLTCIDASREELRAIAQDYWQSGIRHIVALRGD
LPPGGGKPDMYAADLVALLRDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTMFE
GLDNDAETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPASPQA
>W0AKY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sanxanigenens DSM 19645 = NX02|TrEMBL
MTLSLGQLEEARRALDAPLFADLAGDAQVSFEFFPPKSEKMEQTLWEAVQTLAPLGPRFV
SVTYGAGGSTRERTHATVARIASETAIPAAAHLTCVDASKAEIAEVAEAYWQAGVRHIVA
LRGDPPRAGERFVPHPDGFSGASALVAGLKAVRPFEISVAAYPETHPEAVSAGSDLDNLK
AKLDAGANRAITQFFFSPEAFFRFRDRAAAAGIDAEIVPGILPVSNVAQTRKFAAMCGAA
IPDWMDRLFEGLDDHPAARQLVAATIASELCRKLYAGGVRHFHFYTLNRAELSYAICHLL
GLRPDAPALTEKAA
>A0A818UKS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MIILLFVLQAIHKVDHPDMASYEEDLRYLKEKVDYGADFIITRLFFQPATFIKFESDCRS
IGIQCRIIPGIFPIQAYASFKNIVRLAKLDVPEEILACIEPIKYNGEAIRNFGVQKCVDL
CRTLLDSGKIHGLHFYTLNREYATIEILRKLDRCVRPKSYVHRTSNCEEFPNGRWGLPFA
PSFGVLTDYHLFYIKIDATRDALLDEWGHELADKQDVRRMFACYIADEKNGRVKIVHHFP
WKDEDISSETNFIHDHLIKYNRKGILTISSQPAVNGKSSTDSIFGRGIKKWLCLSKSLFR
IFTSEKNIPALRAALKKFPGVNYHFVNKSGEVNETSTEGEQPIALIWGVFAAREIIQPTV
VGPISFMIF
>A0A853PN42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQYMQELTPYFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A4J2BEB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHAPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A5K0XCY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nymphaea colorata|TrEMBL
IPDEIKAALEPIKDNEEAVKAYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILM
>G4HER2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus lactis 154|TrEMBL
MKPDLRQAWENQVLIGDGAIGTYLYQLGFPVGISYEELNLTSPEVIGNVHRQYVDAGAQL
IETNTFSANYDKLSKYGLESKVGEINRAGVRIAREAAGRDGYVVGAVGSIRAGRRSNIST
GELKRYFEEQLSVLLSEGVDGILLETFYDVEEIQLALQQVRKLTDLPVICQFAVENIART
LDGFSMQDAYRILSQEGADVIGFNCRTGPNGIMRALETLSGVMNLPASVYPNAGIADYVD
GEFRYGASPEYFGQMAVPFADLGARIIGGCCGTTPAHIAEIASALSGYVPSPLPEVEPAE
INRIVIQEPAEGNQPERSSEPSLVDLVKERHTVIVELDPPRDLDITKFMKGAEALKNAGA
DALTLADNSLAVTRMSNMALGHLVQARIGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPGSSSVYDMTSFEIIRMIKQLNEGIAFSGKPLKQKAKFVVGAAFNP
NVRHLDKAVARLEKKIASGADYVMTQPVYDPELIVRLREATAHLDIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAMGVQIGKELLDVATKHFNGIYLMTPFMFY
EMSVQLMEYVWEISGRRLSPLFH
>A0A819WR31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MASYEEDLRYLKEKVDYGADFIITRLFFQPATFIKFESDCRSIGIQCRIIPGIFPIQAYA
SLKNIVRLAKLDVPEELLACIEPIKYNGEAIRNFGVQKCVDLCRTLLDSGKIHGLHFYTL
NREYATIEILRKLDRCVRPKSYFHRTSNCEEFPNGRWGLSFAPSFGALTDYHLFYIKIDA
TRDALLDEWGHELADKQDVRRMFACYIADEKNGRVKIVHHFPWKDEAISPETNFIHDHLI
KYNRKGILTISSQPAVNGKSSTDSIFGRSIKKWLCLSKSLFRIFTSEKKIPALRAVLKTF
PGVNYHFVNKSGEVNETSTEGEQPIALIWGVFAENMSRTTFLNVDDTKAGMEDLDKEKIN
KLIQDASKNSKFFKQQQRREEDNRRRIEVKLSKIKSFTPFQIEQAEKSVDRYLAQLDKTR
DLSRTFCHIDMDAFYAAVEMRDNPALQHVPMAVGGESMLSTSNYLARQFGVRAAMPGFIA
RHLCPNLVIVRCDFEKYRADSVKVIEYDENYGSCGLDEAFADLTNHLQIRTNFSEQQRTF
PKEENSTETITFGMTAEEVVQEMRHRIHLATRLTASAGIACNMRLAKLCSDINKPNGQYQ
LESNVEVILNFIRNMPIRKIKGIGKVTALHLESLEIQTVNDIYLKRGILKLIEYPTTFDF
LMRVSNGCGSTTIEHDDLQKSVGHETTFNSVRDSSQLISLCRDLAKKTVDELISHCLLCK
RVTLKIKTVNFENLTRSKTLSSYTDSLNVIADKAVALLKHELDQDIELPALRLMGVRVAD
LKMKSSDLPILQFFSKKSTTTINENVHDVIEDIDNVDEDEEEEREKDENENEEFLSMENS
HLGGCDSKLTHQDDEDSNSSTTACPVCQKLLLGDNEKINKHIDLCLNGEMVRTTIKEENR
RTSPQTKMNKRIQLTQSKSTPPKKRQKRKSDATPQRAHGIDNYFFKTESK
>A6LCV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)|TrEMBL
MKVIDLIRNSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQKPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNDKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A370TLI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Venustampulla echinocandica|TrEMBL
MSGLEYEYVSRVDETGANTGPKPPLDLSHHYSRVTQQRHASDMKDFYKYFQIPGIGNLAG
GLPNEALFPFDTLEAQIARPERFKPTPNDPNSSSKLAHKLATTSIDKPQNALGSSHLTVP
HTSAIQNLLEKIDLATALQYGQAQGYPPLYSFLRQFTRENLHPNCPYLDGPDIILTNGNT
DGFAKAIEALSNIWIEERDWIREREGLLCEEFAYMNAIQTAKPRGLNVVPVKMDLEGMLA
IGPGGLADVLENWDESKGKRPHLMYTVSIGQNPTSGTQSIQRREEIYALCSKYDVIIIED
EPYWYLQYPSAIGKEVEARGTTFPKAQAPHKLGKSTGYPFLDSLVPSYVNLDHDGRVVRL
DTFSKTVAPGCRLGWITAQPSIVERITRITESSTQQPSGFVQSVIAELLIGPQPAAVEFS
KKSRLEQRTFSGWQTDGWVRWLEGLRGAYERRMNEMCDLLEAGRFQLKQGTPIKSSDSDW
AVISKTEMYSFDWPRAGMFVWIQMHFDSHPLWGQLDGPQLATALWAYLTRKPFLVLAAPG
AIFSPTPEIAAEKGWQFFRLCFAAVVEEEVERCSKSFAKGVKAFWLIKSKDELDDDDESN
ARAQVMPGDLVDLVEQINHRLPEVHPPPTDAMNRQIPLHVPFSSHNSNVTEAPSIDHTEL
HGTCTALDTSMEKITDKIAALPPNTNYFSLEFFPPKTAMGSSNLRARLDRMSRALHPLFV
TITWGAGGSTATKSLELAELCQRELGLTTCLHLTCTNMNRALVDKALEDAKALGIRNILA
LRGDPPRPDEYREAEEQGQTSEAMNEEFVWAIDLVKYIRKQYGDYFCIGVAAYPEGHADE
GDPAGQSLEHDLPYLVEKTQAGADFIMTQLFFDVDAFDSFEKRLREHESEAFKTIPIIPG
MMPIQSYQMIKRTTKLSHATLPPGIVSRLDAVRGDDELVKKAGVDILSEIITHIKKTPSP
TPRGFHFYTLNLEKAVSFILERTDLIPSSPSDIESAQFDLPLPLLTINGSQKPSRRESFA
GSDPHNRVITTTPEISHPNYETSALQASEPVEPIISRANTLAISEGEGSLGREATWDDFP
NGRWGDARSPAYGEIDGYGVSLHMSVNQAIKLWGYPTSVSDITSLFIRHIEGEISALPWS
EEGLNEETNTIKQQLLSIIKKGWWTVASQPAVNGVPSSDPIFGWGPKNGFAFQKSFVEFF
LPSNDWKDLHAKLTSPEVAPQVSFYASNIKGDYLSSVTGDARGGTNAVTWGAFPAKEIVT
PTIIEEVSFRAWAEEAFGIWEEWGRVYSKGSRSKELIEQVSNDVWLVNVIHHGFVEQEAL
WELLRA
>A0A7T5E1U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. BL0902|TrEMBL
MTAAPLGYRLQSAAQAGEFLVTAEVMPPKGSDPSHMLQMAQLLKGRVHAVNVTDGSRAVM
RMSSLAASVLLQREGVEAVYQVACRDRNRIALQGDLLGAQALGLRNVLALTGDPVKAGDH
PDARPVFDLESVRLLRLIHQLNSGEDSHGKPLTDGALNLFAGAAVDPQSASWSGLQRRFE
AKVKAGAAFFQSQLITDFERLRKFMDNIAAGSGRPVLAGIFLLKSAKNAQFINRNVPGAK
IPETIIQRLAEAKDPLQEGIHIAAEQVQAARQICQGVHLMAVRREDLIPQILDRGGIAPL
DPLEALRPGQDSVTSLGRKNGSKDRPVGV
>A0A063YU65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. CAMR5420|TrEMBL
MGLLDELKQRILIADGAMGTLLYSHGVDRCFEELNLSNPDEIIHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGGAYVLGTIGGLRTLNKSVVPLDEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALSRLEALGADVVGLNCRLGPHYMIQSLEEVPLPNRAFLSAYPNASLPDYRDGRLV
YETNAEYFEEAAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIVKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDVSSFDLIRLISQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPVYSEEKIVQIYEATKHLATPIYIGIMPLVSARNAEFLHHEVPGIT
LSDEIRARMAACGGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A6G2Q514|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID685|TrEMBL
MRPGERSYSFEFFPPRTDTGERGLWQAVRRVEALSPAFVSVTYGAGGSSRERTISVTERI
RTETTLRPVAHLTAVGHSVAELRRIIGRYADAGIRDVLALRGDPPGDPQGEWRPHPEGLR
YAAELIELLKSVGAFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAVTQMFFRPED
YLRLRDRVAAAGCDVPVIPGIMPATSFAQIHRFAQLSNAAFPPDLAQRLEAVRDRPDLGH
RVGVEHATAMCELLLAEGAPGLHYITLNNSSAAVEIHRNLCPHRAAAPLSAA
>A0A840F4S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia humi|TrEMBL
MSEATASATARAGARSVIEAIAAPHDGPVPFSVEFFPPKDADAEARLWRAVRIFERMNPA
FVSLTYGAGGSTRDRTVRIAGELATETTLLTIAHLTAVNHSVGELRALVGAYADKGIVNL
LALRGDPPGDPLGEWVKHPDGVEYAAELVELIRDLGDFHAGVASFPEGHHRAPDLVADTD
NLVRKLRAGAEYSVTQVFFDVDDYLRLRDRVVAADPEQGAKPIIPGLMPITSLASARRMT
ELSGSTIPRDVEERLMRAAGDGPEEDRAAIRAVGIDLCTEAAERLVAEGAPCLHFCSLNF
AKATSEVLDRIGVDTRGAFAAV
>A0A7K2IMN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis alba|TrEMBL
MAPRGPAPRPRHIRDLLDSGEPLFSFEFFPPRNERSQERLWRAIREIEALGPSFVSVTYG
AGGGTRDLTVETTERIATDTTLMPVAHMTLVDHSVAELRHLIGRLADAGVSNMLAVRGDP
PGDPDGEWVSHPRGLTYAEELVRLLKESGDFCVGVAAFPYKHPRSADVEIDTDHFVRKCE
AGADYAITQMFFDAEDYLRLRDRVAARGCEVPIIPEVFPVVKLSSIPRSEKLSGAPFPRE
LAARFERFGDDAEAVRAFGIEHAQNMCERLLAEGAPGIHFITFNQSTATREIYREVAGHR
DGSAGAARP
>A0A8G2HSS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobiluncus mulieris|TrEMBL
MASGVDWVAPDAGGVLDAPGAPVAFTSVSRGANPKSSRNPTRPVRVSFELYPPRNPDPFS
QAWAGIDRLLDAHPDYVSVTFGTSNSTSASSQSVLAHALQRLGRPVLAHLTCVGKTRTEL
STTITEMLDIGVRDFLALRGDNPKGSVNWEPAPGEFSRASQLVTLLREVAAEYLGDARAI
SIAVAAYPAGTVSARTNAVAALAEKQSAGADFAITQVFYNADDYGALLDSATYQGVSIPI
IPGIIPFTDAARLQRLEGLTGVSVPSRLQAISEISDPEERFLEGLSATLDFVNDLIQAGA
PGLHFYTFNRPRPVLDLVEHLRSRGFTHVDEDSSSELLDLMNAAMQRFSP
>A0A5K0XF06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nymphaea colorata|TrEMBL
VDAGGDLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
>A0A1H7YYG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenoanaerobacterium saccharovorans|TrEMBL
MSIASLFQNRSTIFSFEVFPPKRNSPIDTIYKTLDELQDLKPDFISVTYNAGGNGAASKQ
PTCEIASIIKEKYNIHPLAHLTCVNSTRGEIVAVLDELRNNGIEDILALRGDINPDVPPK
TDFTHASELITFIKEQGGFSLSGACYPEGHCECADVISDIHNLRKKVDAGAEHLISQLFF
DNSVFYSFVERARIAGITVPIEAGIMPVVNKKQIERMVSLCGASLPHKFTKMINRYDGHP
DALRDAGIAYAVDQIVDLISNGVDGIHLYTMNNPYVARKITESISSLRIV
>A0A2G0YWF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ICMP 8385|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKADLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISDMCETLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A1G4JWI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea nothofagi CBS 11611|TrEMBL
MSTIKEKYLSAPGPFISLEFFPPKTQPGKQNLMARMGRMTALNPLFLTITWGAGGTTARK
TLELAALAQRELNIPVCMHLTCTNTDKEVIDQALREARDADIRNILALRGDPPVGEEWDK
TANSSDFQHAVDLVRYIKREYKDDFCVGVAAYPEGHCEGEADGVDHNPLRDLPFLKEKVD
AGADFVITQLFYDVEKFLDFEKMFRDQVSATLPLFPGLMPINSYLLFNRASKLSHASIPQ
SILDRFPPEYRADDNKVRAIGVDVLLEIVDTIYARTNGRVKGFHFYTLNLEKAVAQIVAN
SRCLSKILEEDKDEELVDGIEEIALEDSDELREDNMKKRRRQSSTHNADQTCNRVLLDED
DKNVVSGRQASGAPSRKVVISISQGSGSLGKDATWDEFTNGRFGDSRSPAFGEIDGYGPS
LKVSHQKAYKIWGQPQNFNDIKTLFIRYLEGALDALPWSDLGLSPETALIQEELIQVNER
GYLTLASQPATNSTSSTDKIFGWGPRGGYVYQKSFVEMFVHKQQWENELKPKLEPLSPNV
SFYVGDSNEAFYSNLESNCSSVVTWGVFPNSEILQTTIVEEESFKAWRDEAFSIWLEWSK
LFPRGSTPNTLLRQIHRDYYLVSIVHHDFSKCDALWDLLLS
>J5GT34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis SK304|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIGFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A0T8BXC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FEDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHTLFNHQSLG
>A0A3N0FTI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya undicola|TrEMBL
MSFFHANHQEALNQNLAELQGQINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPPDGGKPEMYASDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRSELSYAICHTLGVRPVTAA
>A0A2I1I0L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schaalia odontolytica|TrEMBL
MPFSDDAYACPCTHDHEPTLLSFEVMPPRKPSLEEPFWNTVDQLLRVRPDFMSVTYGAGG
KDRSNARATVRRLVRDTPIQPIAHLTCVGNSTEEVVSTVYDYLDSGVRTFLALRGDPPVG
HEGWEPGPGGVASATELIHLIRTVEKRRCDAHPGEALRSAFKPLTIAVAAFPAGNPAAGT
TPAQEVERLLVKQAAGASFAITQLFWDAEVYASFVERARRAGVTIPIVPGLLPATDPARL
RRVQDLTGIEVPEYLLTTLADYPHQDARDEFGAVFGSRLIHSVLEAGAPGVHLYTFNRSK
PVLDILALMGVKPDPLRSQASSPETRA
>A0A6Q2Z1M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Esox lucius|TrEMBL
MVNQVQTVDDTWRRCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESVLHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPIGTDWEEEEGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAQSYDEDLKHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKENDAAIR
NYGIEHAVGMCRMLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEKSVYEVFTSYIMAEPNQAGHKVMCLPWNDEPLAPETNLLKDELAKVN
RRGVLTINSQPSINGKPSSDSIVGWGPPGGYVFQKAYLEFFTSSENVTALLQVLKKYEPR
VNYHIVNVQGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDVNPLEQPVEQA
AEQFIQEQSAN
>A0A4Z0QYE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus fructosivorans|TrEMBL
MENKFKESLLDKNTLSVTWELVPGRGANEKAQETAIASAEQAAKGGRVHALTITDNPGGN
PAILADYLGMEIIKMGIEPLVHFTCKDKNRNQMESQLHALDRAKVRNLLVMTGDYTVSGF
KGRPKPVFDLDPSNTLQLISEMNKGLEIPGFKGSTHNQPCDFFAGAAVSPFKSTEAELMI
QYYKLKKKIEGGAQFVVTQLGYDARKCHEVIQFLKINKLDIPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNDEKSAPDKGVGQRMLRAAKLYAILKGIGVAGVHIGGHNLKYEQ
LEYILDKGEELFPKWKDFVKEFDYPQTNGFYYFEKDEKTGLNTDRPANRANRPLDAPAGA
MYTMMRGMHGLLFTPNKKLFPMMRGMYRAAEGKKKTEKGLHAVEHLAKVVMLDCKDCGDC
AMLDLAYLCPMSQCPKNQRNGACGGSLDGWCEVYPKEKKCVWVRAYARLKKYGEEASLDV
PPVPPANWDFYQTSSWSNFFLGKDHSAPILGIKRPESKLPEVKK
>A0A7X2NJY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium porci|TrEMBL
MKTVDLFRQKTVLSLEVFPPKRTAPVGTIYETLDELKGITPDFISVTYGAGGSENSGATL
EIASSIKNRYGIESVAHIPCLNLTREDVLLILERLKKEGIENILALRGDLVPGIEPAGEF
QYAADLIRFIRAHGDFNVIGACYPEGHQESGSLVKDIHYLREKVDAGVSQLITQLFFDNE
YFYRFRERMELAGIRVPVEAGIMPVVNKKQIERMVSLCSVHLPSKFTSMMERYGDNSEAM
RDAGIAYAVDQIVDLTAHGVEGIHLYTMNRPYIANKIYEAVFRLMAF
>A0A6A5V3N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bimuria novae-zelandiae CBS 107.79|TrEMBL
MEKITDKINALPEGANYFSLEFFPPKTSMGFANLQNRLERMSQALRPLFVNVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRALIDDALEQARALGIRNILALRGDAPRSEE
YRDEGQLPEDDSNKDFTWAVDLVRYIRKQYGDYFCIGVATYPEGHSDQSHPEAQDPKFDL
PYLVEKTKVGADFLMTQLFFDVEAYDKFETMLREHESGVFKTIPIIPGLLPIQSYQILKR
VSKLSHAKIPADITARLDAVRRDDELVKQVGIDVLSEIVDHLKGRPSPTRRGFHFYTLNL
EKTVSHILENCHLIPQPLVDDDDDAIELTPGADFAPPVGVQRSKDRRRLSSINSGPRNRV
IVSKPSNASNASLEAPEDEAGVPKDPINTRANTLAISEGEGSLGREATWDDFPNGRWGDA
RSPAFGEIDGYGPSLHVSTAQALKLWGHPIDRDDISMLFKRHIEGDLEAIPWSEQGLSPE
TSTIAKELLALNAKGWWTVASQPAVNGVKSSDPVFGWGPKNGLVFQKPFVEFFLPSADWE
NLQPRLKAHDQITYFAANALGEFEASSEEAVNPVTWGSFTGKEIVTPTIIEAVSFRSWCE
EAYSIWREWQRIYAPRTKSSALLGELRRDSWLVNIIWGDYVEGDGLWRFLIEE
>A0A6I1YJV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. dk4132|TrEMBL
MAEDRIASIAQLVRDGGRSFSFEFFPPKDEAGEEQLWRAISALEPYRPTFVSVTYGAGGS
SRDTTVRVTSRIARETTMTPMAHLTCVGHTRVELEGILDSYAEAGIHNVMALRGDPADGP
RAPWQATPGGLTYATELVELARARGDFTVGVAAFPEGHPTAESLDHDADVLVAKARAGAE
FAVTQMFFRASDYFALVDRVRARGIDIPVLPGIMPILNLNAIRRQGELIGCDVPADIVAR
ISAHDGDPAAVRAEGIALAAELCEELLAGGAPGLHFYTLNRSKATLEIFAALNMSV
>U5F6V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium 5_2_54FAA|TrEMBL
MHPYFMKQKRLLFDGAFGTYYASLYGNEEPCEMANVKAPTRVAAIHEEYLKAGANAIKTN
TFAMNEAVLDCSKAKREELLRQGYRIAKRVATPYQASVFADIGPCVETRTRSAFTQYKEL
VDVFLEEGADCFLFETLPNDHGIHEIAAYLKERCPHVCVLVSFAVTADGYTQQGVPLTKL
VKAAHEDENIHGFGLNCICGPMHMRRLLKYFDTKKDTILIMPNAGYPTILANHTYFRDNS
SYYAQEMEKISSMGVRILGGCCGSKPSYIQKIKERLQEEAVLSLPTPAANDPVLYKDRNP
LRKKLQRKEKVICVEFDPPMDCRIERFMNDAEYLKEQGIDAITIADCPIARARVDSSLLA
CKLHRELGIDVIPHMTCRDRNINATKALLFGLNIEDIYNVLVVTGDPIPAADRQEVKGVF
SFNSQLLAGYIRDLNETTFPHPFFGALNVNAANFKQELLKAKQKIQQGVQAFLTQPIHSA
KGLQNLQQAHRELDAWILGGVMPIVSYRNALYMKNEIAGIEVDDAILSRYEHKNREEAAV
LAVTIAKATIDEMASFVDGFYLITPFHRVEIMQQIIAHIQQMDD
>A0A6J4MNW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Nocardioidaceae bacterium|TrEMBL
MTVSESDDPPADEVSPSGPTRRSVLIDLLQQPRYEVLPLAGTAEEVAEQVATTIPVTVTS
APRRGLEPTLALSEELAGRGYAAVPHLAARLVRDDAHLAEVLDRLGSARVRDLFVVAGDS
DRPVGRFTDSMQLLQAVARLREAGRGEGVRAVGVAGYPEGHPQVTDAELDRALLAKQSDA
DYVVTQMCFDPAAVHGWIRHVRRLGFRRPVHVGVPGAVDRLRLLRIAARIGVGTSLRFIR
RQHDGATLLRRSGYRPDDVLTGLTADAGRGSPEVAGLQVYTLGDVAATERWRRELLERLH
EDGRHG
>A0A848VB00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia sp|TrEMBL
MIENKKSNSDGSPRVSFEFFPPNSEKMDQTLWESIKRLAVLTPDFVSVTYGADGSTRERT
HQAVARILSDTELTAAPHLTCIGASRDEIDAIAREYWDMGVRHLVALRGDPPKDVTDYQP
RSDGYAYASDLVAGLKRVADFDVSVAAYPEVHPEAPNAEFDLDNLKRKLDAGANRAITQF
FFDVDR
>C1F3L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / BCRC 80197 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)|TrEMBL
MNNRLKEIFGDRPVLCDGAMGTSLYARGIFINRCFDELNLSQPELVRSVHEDYLQAGAEI
IETNTFGANAIRLRRYGLQDKVAEINQAGARIARAAVAQLADKQAGNAWVAGSVGPLGVR
LEPLGKVGLDEAQAIFAEQIEGLVAGGVDLLVIETMPALNEAQQAIRAARAVAPELPVIA
MVTVDEESRCLDGTAPEVAAARLAGWGADAVGVNCSTGPAAVLTAIECMAEATDLPLAAM
PNAGMPRAVDGRNIYLCSPEYMASFARKFHKSGVQFLGGCCGTTPNHIRAMKSFLRASEA
QKAAVQHSRSAPIVTETPPAPIEQRSRLGQMIHDRTFVTMVEIVPPRGIDCQKEIDGATM
LAGLGVHVINVPDSPRASARMSAQSLCIQLQQKSGIETLLHYTCRDRNVLSIQSDLLGAS
SIGLRNILCLTGDPPKLGNYPDATAVFDVDAIGLVNIVRRLNHGLDIGGNPIGASTGFTI
GCAANPGVPDIDNEVRRFAYKVEAGAEYAITQPVFDLRILESFLKRIEGFRIPVIAGIWP
LTSLRNAEFMRNDLRVSVPDSILLRMQQAATPELARAEGIRIAQEMLETARPMVEGVQVS
APFGRYTAAAEVLAGILPGTSKSDKAQPASEGMQIG
>A0A414CAJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM34-10|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A1Y2K744|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetofaba australis IT-1|TrEMBL
MRISVELTPRTAEGLEADLALVAQTCPQASAINIPDLARFAVRSWSGCVAAKKRFAHAIP
HIRAWELAPDVAPPMCDLLLAHGIDEVLVVTGDPAADGAAAQSTALQAISAFKKAMPNAR
IYAALDPYRAGFRQELDYVAAKVDVGADGFFTQPFFDLRLMTLFAEMMHDQTVFWGVSPV
TSEKSQAYWERVNKVVFPRDFTPTVEWNINFAHQALDLAEQAGGHVYLMPIRIDLATYLT
GVFERSQDHA
>M6KML7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Pyrogenes str. L0374|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFL
>A0A1G3Z7A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium GWF2_51_19|TrEMBL
MKRWPSLAKCNKMSFSIEFYPPKTTEDGEKLLAVARSLQGLPIEYISITCGAGGSSRGLT
LEYTRLLHQIGFQVMPHVTCVGQDEASIRDILSVYTEMGIDRVMLLRGDLRDNQPAGGDF
SRAIDLVRYTRNHFPSFKIGVAGYPEKHPEAPSLAVDIAHLKEKVDAGADFIITQLFFKN
ADYFAFVEHCRAAGIAIPIVPGLLPVLSLSQAERFCALSGSLLPEALRKALFECTNDKDA
MRAVGVQWTIQQLKELHSASPHFYVLNRAESLCAILKKVSLGLR
>A0A381A634|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella pertussis|TrEMBL
MTQSTAPAFSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRT
LRNLGCDAAPHLSCIGATRDQLRDILAAYREQGVRRLVALRGDLPSGMGGDAGELRYASD
LVAFIRQETGDWFHIEVAAYPEMHPQAESPSADLAHFVNKVQAGADAAITQYFFNPDAYF
DFVERAQAKGVAIPIVPGIMPITNHTQLVRFSEMCGAEIPRWIRLRLAEYGDDKASIRAF
GLDVVSELCQTLLENGAPGVHFYTLNHAEATLGIWKALNA
>A0A096N8D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Papio anubis|TrEMBL
MDHRKARVLPAGHYCPSLGIWASQAGSVRFSVPPSISRNLAMVNEARGNGSLNPCLEGSA
SSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPK
GHPEAGSLEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDALELLNRPTQNERETEAP
>A0A7T2IHR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria welshimeri|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDKAYLAVYPNASLPEVQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLESTKPILEKEVRPIL
ELVPEEVEDEESGERLLDKVKERLTILVELDPPRTFDTSKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGRANEEGMTIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYVQNKQQVQIASK
>A0A355M624|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaeria bacterium|TrEMBL
MKDHSQLNLKLEKDDNRLLKSMKDGNFLVIFEVDTPLANCNIETVTSRYSPFLKAVNSIE
GFKSGLAITDRKHSSECMDILDFANEFCLENRSDHLLFISGRNKTKNSIADLIKSCWASG
FHNIVPVSGTIYKDETLKNMTGISFYESAEVISSMREDLQNNPLLNIGSVVNPFKYSQET
IHTQYYKLIKKLNLGARFVIAQSGWDILKYQELRWYLENRNYFDPCLASITMLSPEKIEK
IISGYYRGVFFSPDCLNSLNKESRLSTSQFWAAQWRRFQLYVAGLRWMGYNGVVISGLDS
EYQVNIAVSRITSILKDISSFDNWREIYRGFLSRSEMAPYPFKYYIYKNLLEENYFDKAE
LTVKDVRKCSRKERLTFNFSKLKKELFPGQKRMLNSNDIASSFYLSSKLCPKGMIHGSCG
ETNHDNTCCLCPAKECLYSRLFRLASWRKNFEPFE
>A0A7W0C623|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosalsimonas propionicica|TrEMBL
MKTESRLEKVLASGALAVTSECGPPRGAVPEKVKEKAELLRGSVDVINVTDNQTAMVRMS
SWAAGILIRQLGLDPVLQMVTRDRNRLAMQADIIGAYSHGINTMLCLSGDHPHFGDHPMA
SNVYDLDSVQLIQAVVKMRDEGKFQGGKDIDHPPKMFVGAAANPFADPFELRVMRLAKKV
KAGVDFIQTQCIYNLDKFETWMKGVCDRGLDEQVYILAGITPMKTAGMARYMKNRVPGMD
VPDEVVKRMESVPKEQQPEEGIKIAVETIQRLKEVKGVAGFHIMAIEWEEKVPEIVEKAG
LLPRPEV
>A0A0F6A8E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas luteoviolacea S4054|TrEMBL
MALTLQEKILDPNQGVYLIGTTPPKLGTDSEQLQTIATKLLDRLHEIEYDGVVIYDIQDE
SSRTQVPRPFPFKQTVDPCEYSKLVRDLSKLDVITYKSVAQRDREEFTQWLSKTKQDFGL
NNLVLVGSPSSSGDIKLGLPEAYQTLNEHSQDFFLGGVTIAERHANKRNEHERLIDKTTK
GCEYFISQAVYDAQATIDLLTSYARTCRQQGIEPKRIILTFTPCGGQKTLEFMEWLGISV
PEATRWRMLDANNTLNESIKICRENLDLILRSCAHLDIPLGLNIESLTNRKEEIDASINL
YRLLKATMELKLAEKQIA
>A0A3N1KY26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stella humosa|TrEMBL
MTDPASVRGPAETLRAPNPVDVSFEFFPPKTPDMEARLWETVERLAPLAPRFVSVTYGAG
GTTRERTHATVARIRRETTLEPAAHLTCVGATRDEIDAVARQYWDAGIRHVVALRGDAPA
DSGAYAPHPGGYGFAADLVAGLRRVGDFEVTVAAYPETHPEAPDAATDLDNLRRKIDAGA
TRAITQFFFDPAVYFRFRDRVRAAGITVPIVAGILPVTNFGQVCKFAGACGAAVPDWLGQ
QFEGLDRDPETRRLVAATVAAEQVRALQAGGVREFHFYTLNRADLSFAICHILGVRPPAG
SPPAPEATP
>A0A451DG36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MIYIINDNSKQNNYESYHLKDKIRISFEVFPPQDSKSEEQLLRSVCLLNQFNPDFFSVTN
SIYAKNRDKTFFIVQKIRSLTKVNVFAHFTTIGLNKLEIQNIALKYWSYGIKHIIALRGD
LPDQYSQKIIYANDLIKLLQSINNFEILVAAYPELHPESCNIQEDLINLKNKADLGVKKA
ITQFFFSIEKFLRFRDNCIDIGLPITIIPGILPILNVNQLKKFSRLTNVYIPKWIFSAFD
EYKDDLSQCIDLSVRIAVNLIVGLYNEGVTNFHLYTLNQSTLSVKICHKLGLI
>A0A2K5ESL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aotus nancymaae|TrEMBL
MDHRKARVLPAGHYCPSLGIRASQAGSVRFSVPPSISRNPAMVNEARGNGSLNPCLEGSA
SSGSESSKDSSRCSTPGLDSDRHERLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCHQRLEEIT
GHLHKAKQLGLKNILALRGDPTGDQWEEEEGGFNHAVDLVKHIRSEFGDYFDICVAGYPK
GHPDAESFEADVKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDIGITCPILPGIFPI
QGYHSLQQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSLCRELLASGLVPGLH
FYTLNREVATTEMLKRLGLWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKNYYLFYLKSKSPREELLKMWGEKLASEESVFEVFVHYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGVLTINSQPNINGKPSSDPIVG
WGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHLVNVKGENITNAPGLQPNAV
TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRAIIQYIHDNYFLV
NLVDNDFPLDSCLWQVVEDTLELLHRPTQNEREAEAP
>A0A0A0JC45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Knoellia sinensis KCTC 19936|TrEMBL
MAPRNIPALLAGQRPSVSFEFFPPKDDVSEAALWDAIRRLERVRPDFVSVTYGAGGSTQD
RTVRVTERIARETTLTPLAHLTCVGASVEDIRRVVGQYAAAGVRNILALRGDPPGDPGGE
WVAHPEGLDHATDLVGLVRTLGNFTIGVAAFPDVHPASRDLDQDVEVLVKKADAGASFAV
TQMVFDADTYLRLRDRVAQHRDLPITPGLMPVTNLKQITRMTQLMGTPLPQRVLGRLEAV
AGDADAVRAVGVEIATELAQRMLSEGAPGLHFITMNRSTATLEVYQNLGLAAGAR
>A0A4Q2QUB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae complex sp. 743-2DZ2F-22B|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMFAADLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A1A6BBU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium gordonae|TrEMBL
MTSGCPKRMEFGPCGGVRPDGQCEMRSGACAFVDFVPWSGPLVVDRPAAAPLVLTDFSCT
PFDRDDVAATAAVLAPSCDAVLVGEHQNRPDFPPTLMGSLLLDAGVTPWITLSCRDRNRV
VLEQELRGLRTIGVDTVLCVTGDGRGYDVRPDVTQTFDLDGLRLVSLAASLGVLPAAPET
PTAPPIAARPARLVEKQRAGAALAVLNHVPFPDMIADFMKSARAQGLSIPVIAAVAVFTD
SVSAAVLQGLPGLELDPAVTERVLGAADPIAAGISAAVEEARALLSIEGVAGVNVSGLGS
ASGARVGAEIKAEVGRLIREGVSS
>X0W2P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKVTEHIEQAKGKTLFSFEIVPPQKGQNIQKLYDNIDPLMEFNPPFIDVTTSREEHIYIK
KDNGLLEEKITRMRPGTVGICASIKHKYNVDTIPHILCGGFTKEETEYVLVDCHYLGLDN
VMALRGDAKKNEAYFKA
>X1IUB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
PPKFCCGAVVSPCSDPIEPQIIKMENKIQAGAEFFQTQLVFEVDKFAEFMNKVKNYKVPV
MAGITILKSVGMAKFMNANVSGVFVPDNLIEELKKDKEKTKSGQTGIEIAARLIKELKGL
CQGIHIMSLGWDRHIPSVLEKAGL
>A0A0F9QSS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MTLREKITMGQFVVTAEMTPPQDADGDIIRRKAVHFHKGVDGVNITDNQTAIVRLSSIAA
AKIALEEGLEPIIQMTCRDRNRIAIQSDLLGAAALGIENVLCLTGDHQRFGNHPEARSVF
DLDSVQLIAMVQRLTQGYFLSGETIKKPPALFIGGAANPFADPLGFRVIRLAKKIQAGAR
FIQTQPVYDLDRFQEWMEGVRAQGLNKKTAILAGIMPVKSLKALLHMENEVPGIRIPKSC
FTRMENAEDQNEEGVKMAVEMILALREIDGVQGIHLMPMMWESVTPRILDEARLLNR
>A0A518RJP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas suaedae|TrEMBL
MPPPLIHPNWSRPATSAIDGYSLEITAKDADALRAVASRIPAATPIAIAYLPGESLDARV
RAAQTIRALGFEPMPHFSARRIESRDAFEAYLGAAVEQAGVQRCFVVAGDPSTPAGPFAD
SASLIATGAFERSGIRAIGVGGHPEGHPNMTEAECFAVLDGKCHEIERRGMAPLIVTQFG
FDADAVVRWLGELRRRGIDAPVRLGVPGPAGIKTLMRYAALCGIGASTAVLRKYGLSLGN
LIGTAGPDRLVATLEAGLTPDHGPVRLHFYPFGGLARTLDWIDGYARATGLDPSA
>A0A6V8IBR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter sp. Gdi|TrEMBL
MMPAQTGPLPAISFEFFPAKTEKSAATLLANAKTLAGFGPQFMSVTYGAGGSTRDRTLAT
LKEMVRETGVPMAGHLTCVGASKKDVNAVAHAYWDAGVKHIVALRGDPPPSAGGVYEPHP
EGYAGAVDLVRGLKDIAPFEISVAAYPETHPAALSPQADLEHLRAKIDAGADRALTQFFF
DAETFLRFRDRAAAIGIDRPVVPGILPVGSAAQAWKFAEMCGANVPQWMRDLFDGLDETP
QTRALVAATVADRLCQTLKAEGVEQFHFYTLNHADTVSALCRLLGRRPE
>X1ATC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MTCRDRNRLALQSDLLSAYVLGIENVLAITGDLPSLGDHPQAKPVYDLDSVQLLWVIERL
NEGYDMAGNELKGKPNFFPGAVVNPGADTEAAFELQLIKMEKKMTVGARFFQTQAIYDVN
TFAKFMKRVEEFKVPILAGIIPLKSAGMARFMNKNVAGVFVPEELINKMAEAEDKTKTGI
AIAANIINELRDICYGVHIMAIGWEKKVPAVLDAAGL
>A0A0F9UV75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MTTPAVSFEVFPPKSVDASFRLWDTAQALAPLGPRFFSVTYGAGGSTRDLTHDSAHVLRR
TSGLPIAAHLTCVGASKAETLEVANSFAEIGVTDIVALRGDPENGASVFTPHPDGFADSC
ELIEALAATGKFTLRVGAYPEPHPESRDQAQNVEWLKRKFDAGADEAITQFFFETETFLR
FRDACAAAGITKPITPGIMPVTNWKSARNFATRCGALVPTWLDEAYNAAIRDDRHDLLST
ALCSEMCSELVAEGVENLHFYTLNRPELTRSVCRALGVTSQTALSDVA
>X1FWF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
PESKPVFDLDSATLIKLVRDMVDSGAINGNEIEAPPTLHVGGAANPNAEPMGAEILKIGR
KAEAGCEFIQTQVVYDLDRTIEFLTEIRKYKVPIFLGIFPMKSYGIAKGFDTFVPGVSVP
KEILAKWKSVKTEARDKKHKKELYDQYNYDF
>A0A4S2MJT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ascodesmis nigricans|TrEMBL
MHKITDKVRALSPGDSFHSLEFFPPKTDAGFHNLLARLERMSQALRPLFVTVTWGAGGST
ASKSLHLAELCQKELELTTCLHLTCTNMSRAVLDEALEGAKATGIRNILALRGDPPRSDE
YMPSGERSNGEEKEFEYAVDLVRYIREKYGDYFCIGVAAYPEGHAEGTAPEFQDPKRDLP
YLIEKVKAGADFIMTQLFYDAQKYTAFEEMLRHDPSGVFKDIIIIPGLMPIQSYQILRRT
TKLSHASLPPSVEQRLMDVKNDDDKVKTLGVDILCEIIHQIRRSLTSSPHARGFHFYTLN
LEKAVSFVIEKSKLLRPITFTADNESAISDEIDDPLLLPANQPANRRRLSSIVRDPRDRV
IVDGPTPIFHPHLEPAHQAGYLQLQDPQSQPPHINLAISEGEGAMGREATWDDFPNGRFG
DARSPAFGEIDGYGPSLHLSRTEAVKLWGYPVTPEDIAEIFVRHIQGEIPAIPWSEEDLR
DESNVIQEELVRLNRKGCWTVASQPAVNGVRSDDETFGWGPKGGFVFQKAFVEFFVAPEM
WERLEKRLRKLGERVSFYAARAGEKGEYRSNMPSQSDALNAVTWGCFRGREITTPTIIEE
TNFRAWKDEAFTIWNEWSSVYPKRSKTRELLRNVAETYWLVNVVHHEYMEPDALWSVLKE
TW
>X1GC67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MIRKISDILREKERTYSFELFPPKTEKGREKLPETAGTLKELEPDWFAVTYGAGGTTREL
TMDIVDELQKRLLVPAMHHFTCVGHSKAELEAIIKKMKEKNICNILALRGDAPEGVEHWE
PAPDGLEYCYQLIELIRSYDSFFSIGVAGFPEGHIDCPDKEIDSRYLKIKID
>W7RQD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus haynesii|TrEMBL
MGFLEDIKSKTLIADGAMGTLLYSYGIDRCFEELNISKPEEIRRVHEAYVQAGADIIQTN
TYGANFIKLSRYGLEDETKQINEKAVRLARSAAGSAYVLGTLGGIRTFNKNSYSLEDIKR
SFREQLYLLLNEQPDGLLLETYYDLEEAREVLKIARKETELPIILNVSMHEEGVLQDGTP
LADGLKQLASLGADVVGINCRLGPYHMIRALEEVPLLEDAYLSVYPNSSLPSLVEGRLVY
ETDDEYFRESAEEFRNQGARIIGGCCGTTPNHIRAMAEAVKGLPPVTEKRVKIRKKAALA
VQNERTEPVLDDLAKQKRSIIVELDPPKQLNFEKFLNAAEELKSAGIDALTLADNSLATP
RISNVACGALLKQRLDMRSLIHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRLE
KKIACGADYFISQPVYSEEQLIKIHEETRHLETPIYIGVMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGNDKQKQAEEGLAIARSLLDAACDLFNGIYLITPFLRSDLTAELTAYIH
QKEKEKTNV
>X1V0W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
SAVMRIGSMAMCHLLKQNGIEPVFQMVTRDRNQIALQSDLLSAWVLGIENVLCLTGDHNH
LGDHQESKAVYDIDSVQLLKAVTGLNEGHDMAGNELNGAPRF
>X1HWF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MNKEMKSGSNLEKLLSRGKFVVTAELGPPKGVNINAIIDKVKILKEFCDAVNITDNQTSI
VRMSSISSAIKIIQLGMEPIIQMVTRDRNRIALQSDLIGAAALGVKNVLCLTGD
>A0A8H5LE12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium pseudoanthophilum|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIEDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIGESRGSKTDSEIMLTMVVNNDFHDNKTIFELLKG
LEVKDLTTPATPLTESVGNGAVNIEPVANGTAATAVAN
>A0A0F9V3X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARNPRFFSVTYGAGGSTQARTREVVR
AVSESGITTAPHLSCIGSEKAQLRDLLSQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAANLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKVRALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAITGF
GTEVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKIVDNLSG
>A0A0F9D605|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
PLGPRFFSVTYGAGGSTRDLTHDSAHVLRRTSGLPVAAHLTCVGASKAETLEVANSFADI
GVTDIVALRGDPENGASVFTPHPEGFTDSCELIEALAATGKFTLRVGAYPEPHPESTDQA
QNVEWLKRKFDAGADEAITQFFFETETFLRFRDACAAAGITKPITPGIMPVTNWKSARNF
ATRCGALVPTWLDEAYSAAIRDDRHDLLSTALCSEMCSELVAEGVENLHFYTLNRPELTR
SVCRAMGVTSQTALSDVA
>A0A6I6FG77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces ficellus|TrEMBL
MPSVPTLGELLASGQRSFSFEFFPPKSDAGARTLWAAIRRVEALAPTFVSVTYGAGGSSR
DRTIEVTQRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGVHDILALRGDPPGDPRG
PWLPHPQGLTYARDLVGLVRRSGNFCVGVAAFPELHPRSRDWESDIRHFVAKCRAGADYA
ITQMFFDPEDYLRFRDRVAAAGCDTPVIPEIMPATDARQIRRFAELSDAAFPEDLAHRLE
AARDDPAAAHRIGVDHATAMADRLLAEGAPGLHYITLNRSTAALDIHRNLGVTPRGALQP
A
>J0N2K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. MSTE9|TrEMBL
MQLTELLCGPKPSLSFEVFPPKKSSNYESIQRAAEEIALLSPSFMSVTYGAGGGTSDYTV
SIAADIQNQFHVPALAHLSCIHSSQEGIREQLSSLRAAGVSNVLALRGDLPPESSVHEDW
EFHYASQLVSEIHRYGGFCIGGACYPEGHTESPSQRKDIEYLKEKVDAGCDFLTSQMFFD
NNIFYNFMYKIRNAGIQVPVIPGIMPVTNVAQIRRIIALSGTVLPQRFRYILDRFGENPA
TMRQAGIAYATEQIIDLFANGIPAVHVYSMNNPLIARKIMENLSEIVGAPAEVSNET
>A0A0D7PW56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. LTSP849|TrEMBL
MTDLTKPATADGQDGHLSSKRPAISFEFFPPKTEDMERNLWDTINRLAPLDPKFVSVTYG
AGGSTRERTHSTISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDP
PGGIGTPYASHPDGYQSSADLVAGIKKRHADIEVSVSAYPEKHPEARDFDDDIDTLKAKV
DAGAARAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARAFVTRAGTSVPN
WLAEKFEGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISHLLGIR
AKSAQKAA
>B1J2Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida (strain W619)|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYKPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDTKDELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLAIWNNLKLPR
>A0A1G5NXJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afifella marina DSM 2698|TrEMBL
MSGSSEFTHPFQAYEAPPLGHSSGSRLERVLRQGRFAVTAELNPPDSANAEDVFEAARPL
AEVVDAINATDASGANCHMSSIGICSLLTRAGYGTIYQISCRDRNRIAIQGDVLGAAAMG
VKNVLCLTGDGVGVGDQPGAKPVFDLDSISLLRALKTMRDEGAFLSGRKISSPPHLFLGA
AENPCVPPLEWRPERLRKKIEAGAEYIQTNYIFDMPVFEAFMARVRDLGLDKKVFILAGV
GPLASARAARWMRSNVPGIHIPEHVIERLEKAEKPGEEGKRLAIELIQQIREIKGVAGVH
VMAYRREHQVSDIILESGVLKGRRPEGSRRARTTPGARSGREAGDEVSSASMETQPSDEG
VR
>M6UNX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira noguchii serovar Autumnalis str. ZUN142|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSLLDPDFVTVTYGAGGSTRDK
TAQILSQISKNYSVPTVSHFTCVGANKGQILETLKGIRSSGIVNLMALRGDPPKGEGEFK
KVENGFGNATELISFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVKNLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A1G3QZ16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium RBG_16_49_21|TrEMBL
MNIDSLYNERFVISFEIFPPKTEAGEESLMQALKELSAYKPGFISVTYGAGGSTREKTLE
LSLKIRDRIGITPVVHFTCVGSGRREIAEYLRMVKAKRISNILALRGDPPQGQERFVPPP
DGFSYANELVTYIREIEVFNIGVAGYPEGHIEAPDLDTDIANLKKKVDAGASYIITQLFF
SNNDFYIFMDKIRRIGITIPVIPGIMPITNMAQVKKVTTMCGAKIPPELMSRLLSCDSKD
EICEVGIEYSIAQCRELMQWGIPGFHFYTMNKSTAVKKIIDALSL
>A0A1I1LLM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp. OV038|TrEMBL
MTDRYYSFEFFPPKTAEGTEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
DGIEAAPHLSCVGSTCDSIRQILKTYRDGGIRHVVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFHIEVAAYPEYHPQAKSPRHDLDNFVRKVRAGADSAITQYFYNADAYFRFVD
EVRALGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTGLCDRLLAAGVPGLHFYTLNAAGATKAVWERLKL
>A0A385AUM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. B006|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTQAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWIAHPEGVRYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAYFVR
KCRAGAEFAVTQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVHLSGAPF
PPALAERFERVADDPEAVRRLGVEQASEMCEKLLDEGVPGIHFITLNRSTATREVWQRLR
AAARV
>A0A0P0DQZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis macrogoltabida|TrEMBL
MTSNLDSLAEARRAAASPLFANLDGDIGVSFEFFPPKTEKMEAQLWDTFHALEPLAPRFV
SVTYGAGGSTRERTHATVARIAATSSVPPAAHLTCVEASRAEIDAVAEAYWEAGVRHIVA
LRGDVPSGGPYRPHAQGYANAIELVAGLKAVAPFDISVAAYPEVHPDADCAQSDLDNLKR
KLDAGATRAITQFFFSPDSFLRFRDTAAAAGITAPIIPGILPVSSVAQTRRMADMCGTAI
PAWMVSLFDGLDDHPAARQLVAATVAAEMSRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVATAKDQAA
>A0A7C3T6A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MDRITLKDRLEQRQGFLVLVELVPGPGQDRRPLIRFLEYLQDLGPGSIPDGFVLAGLTFP
QNPGGVANLEPSALIAQIEHDGLSRDLDLIPHVTCKDHNSIGLSSLLSSYQQQGIQTILA
LTGDRPVGAVGVFELDSIGLLDLVRRMNNQAILRAEPSRLGQVRRFFAGAAVSPFKYTEP
SLLQQYYKMEKKLASGAGYLITQVGWDWRKSQELFLYLDQRGIKVPVFGNVYLLTSRTAA
PRLMHDGKLPGCFVSDQLLERVYAEDLDAHIDRAAQQVAMYRSLGAVGVDVAGVDDPQVL
LEILQRAARISDWQAYKENLYWPPKEVFYLYDLSGKPVPLCQPDKTFKHRFFDASHRLML
DKRYRGFRAFRGLMAFLGADAADSPFYKLFNASERAFKYLVFECQHCGDCFLPENFGLCT
IGGCKKGLDNPPCGDATVDGMCGNDLNRVCIGERIYLAAAAEPEGRRRLLSTINKPRNPE
LLGTSSIINYLFDRDHAMRKRLILIGESIHASIPKVGQVMKELEQGAPESYVKPGPALDY
MRALIESQAEDGADYIAVNVDEFGQEDPSRAVEMMRRYVRLVRQWGRGVPVCIDSGDQRT
LVAGLEEWYDTDLAVRPPLVNSVKTYTMHQILPLRARYDFSVVGLLVSDKAAAGPGGSYS
VDQLVSLAEEIFDAAVGRYGFRPDQVFFDSTVFPLAIDMPMEPGVPGYTYRAFETIRRIR
SMPKFKGVHCSLGISNCVRDLPGRKVGVCRAYLAKAVEYGLDAAIVNVSHKYGTVEPAAE
LLELVDAYAKMDGSPERTQRAMELMARFCQQARRPD
>A0A419E402|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MGEGLGMRERRHTMPIFTPGRRWQPPYLPFKREPFNKRALASIEKAIKGPLFGCRMCGNC
LLQETAFICPMECPKGERNGPCGGSTKEHCYVDETRPCIWYKIYDRSFRMGREDHLLEVL
PPLDWDQVGTEQWSGVINRVKQIGTGKVIGGLLFKPADVRYKMWDDIFEPIREPDWWQGD
NKYHAPNYAEPVSELERRLKAGEFVVTAEVAPPVSCKTDKMCKHIENIKPYVAAINFTDN
PSATPRTASWACSKMALERGAEPVMQIAARDRTRVGLQSEVMGAYDLGIRNILCISGDSM
KMAPSPRGRMDVIDIDSIQMLWILRRMRDEGKYMDGREIKTPPRYFLGAAASPFASEPKF
QALREHKKINAGAQFFQTNLVYDIEHMEIWLNELAKRNILDKVFILIGITPLKSLRMAKF
MNDEVPGVSIPDPLMKRMEAAEKAGNTQEEGVHIALELIERIKKYEGQGVNGLHIMAVGW
EDIVPRIITEGGVLPKNFALPETAGEKVPA
>A0A7C1INN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MAGQRLRDYLKAGKFAVTAELTGGPGYQIGPFVQFLKDWQTSDKQLPQGFHFAGVTFPQN
PGGAANLDPTDALAVMEAGGLLDGLDYIPHLSCKDSNTDALISTLVGYRTRGVESVLALT
GDKPLTAKGVFEVESVGLLAMIQKLNRDALLKAKPGQWDAVHRFFAGAAVSPFKYTEASL
MQQYYKMEKKIAAGARFLITQVGWDWKKSVELMRYLKDNAIDTPVIGNVYWLTTRTPAPR
LMHDIKLPGCFVSDALLAQLQSESVDEHIERAAQQTAMYKAIGAAGVDIGGVHDFEIFMR
ILNRAAEIGDQWEQYKDNLCWPAEKAFYLYDDNGKQTALSAPKKKCNERFFDLMHRAILD
PKHCGFRAFRATLRAFRADRDGSFSNKAFNGIEKPIKYWLFECKECGDCYLPENFGYCTI
GGCEKGLDNAPCGDATVDGWCGNNLERLCIGERIYDSAAAEPNGRQTLRRQINRPRKPEL
EHTSSIINYLFGKDHTMTTPLIGIGEAIHASIPKTGQVMRELDALGPDAYTTSSGPLDYI
RALIEQQADDGAAYIAVNLDAFGEADPQRAVQMMVQYARLVRRWGKGVPLCADSSNDDVL
KAGLKEWYNTDQAVKPPLLNSIKVYTADAMMPLKKQYDFAFIGLLVSEDKPTGPGGSHSV
EELFRLAKTLFDKAMTYGFKPGEIFFDSTVFPIAIDMPMEPGVPGYTYRAFETIKRIKND
PQMKDCHCSLGISNCCRDLPGRKIGICRAYVAKAMEYGLDAGIVNTAHRYGEKDPDPELV
KLIEAYAKLDGSPERLNEAMTLMGQFCAATRKV
>A0A8A5KBL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter rubeus|TrEMBL
MKIPEHIANANGKTLFSFELIPPLKGQSIQGIYNAIDPLMEFKPPFIDVTTLREDFIYKQ
HPSGLLEKLSYRKRPGTIAICAAIMNRYKVDTVPHLLCGGFTKDETENALIELEFLGIEN
VLVLRGDARLGDSSFVPTPNGHCYATELLQQVVNLNNGIYLHEDHGNTAKTNFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVEMGAQFIVTQMFFDIGKYKEFVNGCRANGINVPIIPGLK
PITSSKQLVTLSKTFHIDIPEDLSDAIHACATEKDVKEVGIEWMINQCKELIAFGAPVLH
FYTMSNAGPTKRIAEAIF
>A0A8F7XP35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria perflava|TrEMBL
MNHAREIAALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHSIVKRIKQETGLDAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVMMGIDVEIVPGILPVTNFKQLTKMAQVTNVKIPSWLSKMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRPR
>A0A6N7TSR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. BIOML-A1|TrEMBL
MKDVREILKKRPLLFDGGMGTYYKAKPGQECEQANLLDPDGILTVHRAYLEAGADAIKTN
TFGLPRMAAAQNPMWEAMADEGWKLAAQAAAKTSAAVFADLGPAPDTEALPAAQIYTALA
ERFAALGAKNFLFETLSSDAGVAEAARQIKEAVPDAFVLVSFAVLPDGYTREGRHCAELV
RSMTACGAVDAVGLNCVSAPGAMRALVQQLGETELPLAVMPNAGYPVVTRTRVQYQGRPE
YFARELARLAAEGVRILGGCCGTTPAHIAALRAALDALPETLPAAPAAAVSTAAKPEVEK
DDAFLRKLNTGKKVIAIELDSPKDADLTGYLDGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGLNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPLTVFGALNLNARNFDVELRRAQEKLQNGMSGFL
TQPVLSAQAVVNLKKTRETLGEKAKILAGIMPVVSQRNAIFMENEVNGIHVDAEIIERFA
GLDRAQGEELGLEVSVKAAQAAAPYADGFYLMTPFNRIALMERLIARLKDEGIAD
>A0A3D1EWH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHINDIFDEQPTTLSFEFFPPKNEKSAESLYQAIEQLTELKPSFVSVTYGAGGSTRELTH
DLVVRIQQQSQLNPIPHLTCVCHQEPEIASILERYAAAGVGNILALGGDLPADKPGYDRK
QDAFEHATDLVSYIKQFGEKGNHPDKRGFGIGVAGFPEGHPATPNRLLEMDYLKAKVDAG
ADYICTQLFFDNRDFFDFCERCELAGINIPIIAGIMPVSTVTGMKRMAELSAGSRFPAPL
IRAIQRVQDDPDAVKQVGIHWATKQCMDLLDNDVRGIHFYTLNKSDTTQQIYLRMGLNDS
TPVTGK
>A0A0R1SK52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus versmoldensis DSM 14857 = KCTC 3814|TrEMBL
MAKKNTGPRLSFEVFPPNSQGGVDKLTDTLDELKNLDPSFISVTCSNHKLNYEKTTIDLA
KYVHDKLKCSTMVHMPAAYVTKKQVSRILDQLEAMNINQVLALRGDIIDGYVPEKDFRYA
SDLTRFIKQEKPNFQVSGACYPEVHPDSDNRIDDIKHLKAKVDAGCGQLISQLFYDNEQF
YHFQEECAIADINVPILAGIMPIINRKQALHVIENCSAHLPKKFVAILEKYQDNPVALK
>A6FA25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moritella sp. PE36|TrEMBL
MKYSIELVPRSWETLNTEAEEVSQFSQINTLNIPDLLRFDVRSWDACDRLQDKFDEVIPH
LRAIDFDLRNGFPLTDFFRHSKINSVLVVEGDPPQDISHRTYRNTSCELIRIIKKELPYM
KVYAAIDQYRTSMRKELDYIHDKLDAGVDGFFTQPFFDLKFLDVYMDMLQGTEVFWGLSP
IHSETSKSYWENKNDVVFPSDFEPTKEWNIKFGRAMIKKVQAKDDNVYFMPIRANASEYL
DKLLAED
>H7ELC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema saccharophilum DSM 2985|TrEMBL
MIFPMKIIDKINEKKVTVSFEIFPPKKQDAFDSVKNTAIELTSLSPDFISITYGAGGSTQ
SNTAELAAAVENAGTAALAHLTCVRSTREQLTESIGTFKSKGIQNILALRGDFPRDASED
ENVFPSGLVHASDLVPVLKDAGFCVGGACYPESHPESANRDDDIELLKKKVDAGVDFLTT
QMFFDNDMLYSFLYRLQSAGIRVPVIAGIMPITNANQVSRMIDLSNAYIPRKLLSICDRF
RNSPNAMRQAGIAYATDQIIDLISNGVRGIHIYTMNKPDIAREIVRNVDSIVAAVNGESA
AK
>A0A4Z1PXF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium larrymoorei|TrEMBL
MTNKDTDRHPSGDFKLSFEFFPPKSPDMDVQLWETVEELSRWNPDFVSVTYGAGGTTKAP
TLEAVRRMISVAGLATASHLTCVDASKREVHEVVDEFREIGVTHFVALRGDPSTGIGTAY
KPHPEGYENAAALVRGLRELGDFEISVSAYPEKHPESESDAVDIEMLKLKADAGATRALT
QFFFDNDVFERYMERVTKAGIKIPVVPGIMPIQNLTQLKRFAGRCGTSIPSFLDDRFAGY
DDNPAERAKVAADVAAEQIFDLQRRGVNEFHLYTMNRAPLVNAVLENVGFRPARKSAA
>A0A3A5QAL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. AM43-2AT|TrEMBL
MTKQTPSLSFEVFPPNPEVGNAKLLRALENMQELAPHFISVTASNNKYNIKETTVALANH
IQNELSIPTIAHLPAIYLSKEKVADTLHELDQVGVHRILALRGDIIPGIEPLKDFRYATD
LIEFIKTEAPHFDVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVHHATKALFEHQPNLEVI
>A0A2M9K805|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02120-2|TrEMBL
MALGTASTWSDRAHTVRDLLASGSSYSFEFWAPKTEKGERNLWEALRRVEAVAPSFVSVT
YGAGGSTRGGTVRATEQIAADTTLTPVAHLTAVDHSVAELRHVIGQFADAGIRNMLALRG
DPPGDPMAPWVKHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVDK
CRAGADYAITQMFFHPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
DAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A4R5CYJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium hiemivividum|TrEMBL
MKVTEHIEAAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMDFNPPFIDVTTSREEFIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYTVDTVPHVLCGGFTKEETEYLLVDCHYLGINN
VMALRGDAMKDEQSFVPKSGGNNFAVDLVQQIDQLNQGKYLHDVMHIDNKADFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVDKARAMGIMVPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIHAVDQCKTNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A1Y4NZB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp. An169|TrEMBL
MKIIDRLREDRIHISFEVFPPKTDEGYDKVVSAVDEIAGLNPSFISVTYGAGGGTSKNTA
KIATHIKDDLHVLSLAHLTCASSTKDEVRDVIRNLKSLGIENILALRGDIPADMTFPAED
RFQYAYELVEEIRRHGDFCIGAACYPEGHVENEHKADDIRYLKQKVDAGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSASQMKKSKDLSGTVFPRRFLSILDRFGNSPA
AMKQAGIAYATDQIIDLLANGIKNIHIYSMNKPDVAAAIMSNLSEIIKA
>E3JWM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia graminis f. sp. tritici (strain CRL 75-36-700-3 / race SCCL)|TrEMBL
MKISQKLAAAESENRISWSFEYFPPKTDNGLTNLYDRICRMSQLGPIFIDITWGAGGSTS
NLTTEFVKTAHEQFGLETCMHLTCTNMPKSKIDTALKEAYEFGCENILALRGDPPKGSTE
WTATEGGFEHAIDLVRHIRAEYGDHFDIAVAGFPEGHMHSTLSREQQTIYLKEKIEAGAN
FIFTQMFYDVDIFIDWVREIRAAGITVPVIPGLMPIQSWAQFKRVTNFSKTIVPQYFLDK
LEPIQSDDQAVREAGTKLVADMCRKILNSDLGIRILHFYTMNLERGTKMILDELNLNPSR
DITNPLPWKMSLLGKRRSESIRPIFWANRAKSYLSRTETWDEFPNGRWGDSRSPAYGELD
GYGININAATMETLKGLKKFPTSLADLARIFANYCGARFPGEEPVKYLPWSDIPLSEETN
KIEDVLVKINKRGFLTINSQPAVDGAKSSDPVHGWGPRGGYVYQKAYLEFFCCPEKFQSL
TERLEKDPDVTYYAVTKTGDLVTNNTRPGPNAVTWGVFPGKEIVQPTIVELVSFIAWKDE
AFELGHQWAELYKEIAPESARFIHQIMDSWYLVNIVNNDFRKSNDDSEHSALFQFFGPEP
VIVDQDDLPPTTNGLSHPNGLPKTNGSSTPAISEVNGELKNLAI
>A0A7X5KRZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium MD329|TrEMBL
MFIKDIFNSKKPVLSFEIFPPKQESKVEEVEKAVKEMANLPIDYMSVTYGAGGSNSKNTA
RIASYMKDNLSVTSLAHLTCVANTKDDIENILNEYKSLGIENILALRGDKPRDYDGELFP
GYSHASELAEAIKKHGCFCVGGACYPECHPDSPNIDVDIENLKNKVDAGVDFLVTQMFFD
NNAFYNFRDKMIKKGINVPVTAGIMPLTNAGQIQRMAILSGGASMPSKFMKMISRYEDNP
AALKQAGIAYAVDQIIELVSNDIDGIHLYTMNKPETAEKIVTVINSLF
>A0A6B4BXJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGESLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELEENNIENILALRGDMPNGKNIIGE
YNYAFELIEKIKGNNNFGVSGACYPEGHIECESLKQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQQKNINVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A7T7REQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ZYC-3|TrEMBL
MALGSASTRTDRARTVRDMLATGKETYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSIAELRNIIGQFADAGIRNMLAVR
GDPPGDPMADWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDRDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDSAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A6L9GPQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIIDRLNEDKIHISFEVFPPKTDAGFDKVLDATDKIAALKPSYISVTYGAGGGTSKNTA
RIASHIKEDLGVLSLAHLTCASSTKEEVRSVIANLKQLGIENILALRGDIPEGMIFPSED
RFRYAWELVEEIRKHGDFCIGAACYPEGHVENEHKADDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSATQMKRSQELSGTVFPRRFLALLDRFGGHPE
AMMQAGIAYATDQIIDLLSNGVKNIHIYSMNKPDVAAKIMSNLSEIIRC
>A0A7C9JBS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbidospora solisilvae|TrEMBL
MALGLPSRFPDRVATVRELLAAGERSFSFEFMPPKTPEAERQLWRVIRELESLKPTFVSV
TYGAGGSTRDRTVDIVERIAHSTTLTPVAHFTAVNHSVRELRHLIGRFADAGVRNILAVR
GDPPGDPMGEWIAHPEGVHYAEDLVRLIRQSGEFCVGVAAFPYKHPRSPSIESDVDYFVR
KCRAGADYAITQMFFEADDYLRLRDRVAASGCDTPIIPGIMPVTRFATIARSEQLSGAPF
PAKVAERFERVKDDPDAVYQLGIEHGVKLCRRLLDEGAPGIHFITFNRSNATREVYQALM
PAVPVV
>A0A316PRT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MNIQEYIRTHKLITDGAFGTYYADRFRTQDMPELANISFPQRVTAIHQEYIEAGARLLRT
NTFASNTILLHADMNEVRANITAAVNLAKEAVKGREDVFIAGDIGPIPSDEVISREELEE
QYYQIARVMLDQGLKILTFETFHELQYILPAIGRIKTEAPDTFIMVEFTVNQFGYSSAGL
GVKSLLKDASACKDIDAVGLNCGIGPAHMEKLLDQAGVGISGTKYRIALPNAGYPRRISS
RIRYSNSSAYFAAKVEEMAAQCELDIVGGCCGTTPEFIRQLSQGLDTTPCPPRTAAEISK
TEQVVPQRKGFLYDEQGNLKKKKLIAVELAPPMGADDEKVLEAARLLQKSDVDVLTFPDS
PSGRTRIDSVLMAEKVRRETGMEVMPHICCRDKNAIAMRSLFLGAYINDITNMLIITGDP
VPSLVRQTIKAVFNFDSVGLMKIAQEMNTENFPARPLSYGGAISQGRKNLDVEIMRVKKK
MEAGAEFFLTQPVFSKEDAERVRRIKQETGTRILCGIMPFVNKRNALFMKNEIAGIIVPD
EVIARYPENGTKQEGEAVGVEIAREIMEFTADFADGYYFSFPFNRVYLLEQILR
>A0A524Q715|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chrysiogenales bacterium|TrEMBL
MATGLVTPVSFPGRSRQMESIIERMRGRPVIFDGAMGTMIYGKGVFINSCYDELNVANPE
LISGIHREYRDAGAEVIETNTFGANRMKLSAFGMGERVDEINRAAAALAKDVAEDRLWVA
GSVGPCIHAYEVYEPTRAQEFESAFMEQCRSLADAGVDFIQLETFSHLAELKIAASAAKK
TGLAVSASFSVNEEGLATDGNTIEDFTRSLCIDPNVDILGINCGMGPSNFLQALERIIHL
CSKPVVVMPNAGYPQDVGGRTMYLTSPDYFATYAKRFIQIGARGVGGCCGTTPEHIGNAV
SIIKNLGELKTYRKIREVAVLPENVSPVPIEQKSRFAERLSSGLPVTTVEVVPPRSIDLT
AMLERVARCHERGVDAINIPDGPRASARISNLVAAVKIQDSTGAEAIPHFCCRDRNLMAM
QGDLMGGYVSGLKNFLLVTGDPPKIGDYPEMTGVFDVDAIGLVEMARNLNRGHDLAGHPI
GAPTGILIGVAANPCAVDLTREVERFLRKIDAGAEYAIPQPVFDPEALIRFLEMTSAHHT
TIPVVAGVWPLSSYRNALFMATEVPGVVVPPAILDRMSSCSSAEESRIAGIEIALEIKSK
ISKYVQGFQVSAPMGNVETALHVLELL
>A0A3C1WVH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MNRLKDILNQKILITDGAMGTYYQSLYPDDEDIVERAVLKYPDRIKSIHKSYIESGASLI
RTDSFAVAGPFIDSDEERVEIARKSYSLAKETIEESGKDCVVCADIGTVFDPAMNGEILT
SLKPVIDAFLDEGAAVFDFETQTQTEGLSDIFSYIKEKNPDAEIILSFSINKTGMTTGGL
SVDNIMRYGAKEANVDVYGFNCGVGPSHMAQLIEKAAFYTDKPFIVMPNAGYPYTLRGRQ
IYRGDSDFFTEKIKAIISAGADIVGGCCGTSPEFIEKLSKEFAEKKPEQKNIEAAEKKTT
RTFSSFYKKIESGEKPFIVELDPPFDSDITKVMNSAHTLADAGIDIITLSDSPMGRSRMD
PMLLGAMMQHETGVDVMPHVACRDRNIIGLRGALLGSYAAGIRHFLMITGDPVPAADRSQ
ITPVFDYNSIRFMNMAKLLNDEAFSKDRIVYGGALNYHGRNADAIARRMSLKMEQGCSFF
LTQPVYGDEDIERLAYLKEKTGAKIMAGIMPLVSYKNALFMANEMPGIHVPQEIVDLYSP
EMSREEAEEVAVRVSLDIADKMKETADGYYFMVPFNRVKLICRIIEQIRKK
>A0A6B4FTN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MNIKNLFKDKKVVFSFEIFPPKTTSSIQTIYDTLDDLKGLNPDYMSVTYGAGGSVKNNNT
IELSSLIKNKYGIEPVSHLTCINLTKKDVEYYLREFEKNNIENILALRGDVPIGSKITGE
LNHANELIKYISDNGNFNIAAACYPEGHIEHKGLYREIESMKRKEEAGVSYFISQLFFDN
NLYYNFQDEVRAANINLPIEAGIMPVTNKRQIERILSLSGASLPDKFKRIMERYEHNPEA
LRDAGIAYAVEQIVDLISTGVDGIHLYIMNNPYVAKRISQSIQSILLTVNQI
>A0A371RJZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvularcula marina|TrEMBL
MPPVKVSFEFFPPKTDKMGETLWTSVGKLAPLKPTFVSVTYGAGGSTRERTHKTVERIVS
ETELSVAAHLTTVEATKDTVDDVLRDYWAVGVRHIVALRGDPPAGVGETYVPTPGGYANA
AELTVGAKGIADFEISVGCYPEKHPESASVEADIDYLKAKVDAGATRAITQFFYDNDVYE
RYVERVRKAGIDIPIVPGIMPISNFKSLCRMSSLCGASLPKRLHALFDDLDDDPAQRQLV
AATIAAEQCVDLQKRGIDQFHFYTLNRAELTLATCRMMGLTPAVTEAA
>A0A151BP68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon B26-1|TrEMBL
MEGCKPVSRPVFSELMAQIRAGKFVFTGELEPEKTIDLTETLEAARRLKGYVTACNVTDN
PQAFAYISSLAASYIVQKETGVETIYQITCRDRNRIAITSDLLGAGALGIKNVLALTGDH
TTLGDIPQAKPVFDLDSVQLIRTARMMVDEGVDVSGNEIKDPPKFHVGGGANPNADPLEP
ELIKFGKKVSAGAEFFQTQVVFDIETVKRFFDEIKGYNVPVLIGIFPLRSYGVAKYFDET
VPGVKVPEELMKALAEAKRISDKKRRRQRYNEINLEYFTNLLKEIKKTTPAAGCHLMSVG
YE
>A0A6B4TCL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MNIKNLFKDKKVVFSFEIFPPKTTSSIQTIYDTLDDLKGLNPDYMSVTYGAGGSVKNNNT
IELSSLIKNKYGIEPVSHLTCINLTKKDVEYYLREFEKNNIENILALRGDVPIGSKITGE
LNHANELIKYISDNGNFNIAAACYPEGHIERKGLYREIESMKRKEEAGVSYFISQLFFDN
NLYYNFQDEVRAANINLPIEAGIMPVTNKRQIERILSLSGASLPDKFKRIMERYKHNPEA
LRDAGIAYAVEQIVDLISTGVDGIHLYIMNNPYVAKRISQSIQSILLTVNQI
>A0A6I4I2P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter ginkgonis|TrEMBL
MKITEHIANAKGRTLFSFELLPPLKGSSLQGIFNAIDPLMEFKPPFIDVTSSREDNAYKE
RGNGLLEKVTYRKRPGTVAVCAAIQHKYKVDTVPHLICGGFTKEETEYALIDLQFLGIDN
VLVLRGDARKGDAGFIPTPGGHCYATDLLKQVTNMNEGIYLHEDQPSAYKTDFCIGVAAY
PEKHFEAPNLKTDFKYLKQKIDGGANFIVTQMFFDNSKYKEFVTQCHENGINVPIIPGLK
PITNLKQLVSLPKIFHIDIPEDLGDAIQACKNDNAVREVGIEWMINQCKELMEFGAPVLH
FYTMGNAEPTKRIASALF
>A0A4P7JLL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassotalea sp. HSM 43|TrEMBL
MNAKARQLDLLNRTVRDLDRDLNVSFEFFPPNSEQMETTLWNSVERLEPLNPSFVSVTYG
AGSGTRDRTHGVIKRIQRDTSLVAAPHLTCIDASKQELIDIAKDYWQSGVRHIVALRGDL
PNSSEKPNMYASDLVEVLKGVADFEISVAAYPETHPESPNAQFDLVNLKRKIDAGATRAI
SQFFFDIDAYLRFRDRCVAVGIDVEIVPGILPVSNFATLKRFAGLTNVHVPDWMGKLYEG
LDDDPTTRNMVGANIAMEQVKILRSEGVNDFHFYTLNRSELTYAICHTLGIRPQQG
>A0A7U9XFJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKVTEIFEAKKKEGKPVLSFEIFPPKKEEALKNIDATLERLCSLHPDFISVTFGAGGSAA
NNQTVEIARKIKNNWGVEPIVHLTCLHYGKEEISGILRELQEAGIENVLALRGDVNPNVP
MKHDFRYANELVAYIKEQGDFHVSGACYPETHLEAPNAIADIHNLKKKVDAGAGHLVSQL
FFDNEAFYSFYEKTRIAGITVPVEAGIMPVTNRAQIERMVNICGATLPRKFERILHKYED
KKEALFDAGLAYAINQIVDLIANDVDGIHIFTMNNPKVAGRICDGIKNLI
>A0A418VB68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus cavernae|TrEMBL
MTTRISLELIPRTRSGLRAELEEVKQTFPGVDTINVPDLARFSTRSWEGCAFARPHFRAI
PHIRAIDLNPKEPLPMAEPLAAHGIEEVLIVTGDAPSDMNRRVYNVDAEQAIRRFARELP
HVKVYAGIDPYRQSLARERDYMERKLEAGAVGFFTQPFFDLRLMDAYADLVPDGAEVWWG
VTNVTTEGSMTYWATRNAAVYPRHFDLSLEWNRRLAAGALQFARDRGQHMYFQPIRTKVV
DYLGGIL
>A0A3D2I3X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MIKDLFHTNRPTYSLEVFPPKKDADVSVIYDALDEFKTLHPSFISVTYGAGGNTAENTFA
IASYIQNQCGIEALTHLTCAAIPDRLFLKNFLTNLYRNGIHNLLALRGDKPQWMSDEQFD
ARFYDHASDLVTDVKEMFDFSVAGACYPEVHQEAASLSEDIANLKIKVDKGVDFLITQLF
YDNETFFRFLDEARNAGITVPILPGLMPITSAGQVKNIIGMSGTKIPKELTDAIEKYKDN
PADLKKAGLDYSKRQMENLLAHGVDGIHLYSMNKVEIARAIYE
>A0A2M6VC58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. JirII-31|TrEMBL
MTNNSLSIEFFPPKTAEGAEKLRAVRQALYVLKPQFCSVTYGAGGSTQAGTLSTLNEILA
EGVPAASHFSCIGATRDSVRQQLADFKAMGIRRLVALRGDLPSGYGGSGEFQYASDLVAF
IRAETGQDFAIEVAAYPEIHPQAKSAEADLQAFATKVKAGADSAITQYFYNSDAYFRFVE
DVQKLGVDVPIVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGFGDDLASIKAFGLDV
VTDLCDQLRSAGAPGLHFYSMNQSAATLAICRNLGLVV
>A0A3D3RZI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A3D1Q478|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MIKDLFSQKQTLSFEVFPPKKDDEFTNAQNVLHQLSELQPDFISVTYGAGGSRSKRTVEL
ASFIQNSLHIPAVAHMTCVGSSKEDILTVTDDMKQAGLSHVLALRGDRPTWMDDAQFENR
AFAHASDLTRFLKEHTDLEVAGACYPEKHFEAESLDSDITYLKEKQEAGAAFFITQLFFE
NDSFYRFLEKKNHAGITLPVCAGIMPITSAKQLGTTVTLSGSSVPKELADIIATYGENPE
DMRKAGIDYAIRQILDLKQHGADGIHIYSMNKPKTTRTIVEAIR
>A0A3D4SFL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MIQEKEHKGVVFSCEVFPPKRDDDIYQIYKTLDEIKTLKPDFISVTYGAGGSNSKKTATI
AAYIQNICEVEALAHMTAVGMDEASLRALLFELKKKGVENILALRGDKPRTMSQEEFDQR
YFKYATDLIPEIKKNGDFFIAGACYPEVHPESKNQEEDIQHLKQKVDLGLNCLITQMFFD
NNAFYSFMDKLEKAGIDIPVHAGIMPVTAAKQLGTSVTLSGSSVPVEMSNMIAKYGENPE
DMKKAGIEYAVNQILDLKKHGVAGVHIYSMNKADVTKQIYEASF
>A0A3D2IQB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MISPRFSDLMRERMTLSFEIFPPKTEAGMKKLPGILDELVSFGPDYISCTYGAGGANIGM
NQEALQLIRERTVACTHYTCVGVTREAVRQHLSGYLDRGITHILALRGDYPMGWSHTGGD
FAHASDLVRFIREEFGDSFEIAVAAAPGGHVECTSEDDDIAYLRMKQDLGADYLITQLCY
DLEQFKVWRDKVDKAGITLPIDVGIMPVTTKHSVMTQCFSRNACAVPRELALVLTHHWFD
KDQDGNEIPQVKAAFREEGLSYSAWLLNQYLGLGINGIHLYAMNRAE
>A0A413QFI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus bromii|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYGAGGNGSKNRT
CEIASKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYIALQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A2J0PDV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter kobei|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSASIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>Q4C833|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocosphaera watsonii WH 8501|TrEMBL
MINHFRQAVQNKEFLITAEVAPPKGGNPTRMLEMAKQLKGRVHGVNITDGSRAVLRMSSM
AASALLLQYGIEPICQMTCRDRNAIALQADLMGAYALGLRNVLALTGDPIKAGDHKRSKP
VFEVESVRLLKMIDKLNEGIDFNDKTLADEPLDLFPGAAVDPQSRSWSGLQKRFERKVAA
GAQFFQSQLITDFEKLDKFMHQIAANSDKPILAGIFLFKSAKNAQFINNNVPGVEIPESI
IKRLGEAEEPLKEGIKIAAEQVKQAQQLCQGVHLMAVKREDLIPEILDQAGIPPMVSQ
>A0A3D1WQU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKFSDLMKKRQTLSFEVYPPKTEKGMNNLPGMIRRLGELQPDYISCTYGAGGSNVGKNRE
VLREVEKVAVPVTHLTCIGQTKESVRRQLQAYLDQGVTHILALRGDIPYGQNGTGGAFSH
ATDLVAFIRKEFGTAFEIAVAGTPGGHVECSSLEADIMHLRQKQDLGADYIITQLCFDMD
VFRRWYEAIRKAGITIPVDAGIMPVISKKSVISQCFSHNACPVPRDLALVLTHNWFDTDP
EGNEIPGAREAFREEGIAYTVRLMEQYIAEGIDGIHLYTMDRSEDVREVLQRAGLR
>A0A3D0LFS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MIEKNGKKIEFSCEVFPPKRNEDMYEIYKTLDELKLLGPDFISVTYGAGGSNSKKTSTIA
SYIENICEVQALAHVTAAGVTPEKLADLMAELKKKNVNRILALRGDKPRDMTEEEFEARF
YKHASDLIEVINQDDFFRIAAACYPEKHPEALTVEEDIRFLKKKVDMGADDLISQMFFDN
DKFYSFLERLDKAGVKASVHAGIMPITAAKQLGTSVSLSGSSIPTKLSNLIAKYSEDPAS
LKKAGIEYAINQVEDLIDHGVDGIHIYCMNKSDVTREIYEAII
>H8GBE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora azurea NA-128|TrEMBL
MGLRDRARGRGPAPRLPRRWLDEARFEVLPLDAVLDETAHLPENTTVTVTASPTRGLDAT
VQLCEKLAAQRLRVVPHLAARQVRDATHLRDVLDRLAAVETDEVFVIAGDASTAAGPFGD
GLSLLRAIEESGRRPRRIGVPCYPEGHPTVPDDALWEALRAKQPHADYAVSQLCFDPGVV
CRFLRAARQRGVTLPVLVGVAGVVSPAALLRVGSRVGVGDSLSFLRANRSTVAGLVSRHD
PGRFLAGLADRAADGECAPAGLHFYTFNRVSATTAWLTAVRGSHTE
>A0A374D737|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM36-2AA|TrEMBL
MKMKELFDRGEFAVSAEVGPPKGIHVDELVEEAKTYLTGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMFGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A221UR56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenibacter algicola|TrEMBL
MKVTEHIKKAEGKTLFSFEIIPPVKGRSIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKRLTRMRPGTVGICASIQHKYGVDTVPHVLCGGFTKEETEYVLVDCQYLGIQNV
MALRGDARKEEQYFSPTKGGHAYASELVKQIHALNHGNYLHDKVETVHSADFCIGVAGYP
EKHLEAPSLITDLKRLQEKVEAGADYVVTQMFFDNQKFFEFVEAAKKMGINVPIIPGIKP
IAVKRHLQLLPQVFKIDLPQDLIDAVDDCSTNADVRQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIEAIAKELF
>A0A1G0ZWK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium RIFOXYC12_FULL_60_16|TrEMBL
MSTERLHIEILTPKQNSENLDDDLAKFADKYNQIMEQDHIACITDNPMGHLSFQATEIIP
ELGLPVKPENLMIHLNTFHTKEALDGILQTAITMGVRSLLVISGDGSERLPKLAPESIGL
ACNAVTSVELLGYIHKTHPGKFDCGVAFNPYEPQDHELEKMQRKVEAGATFIITQPVVER
HDAVDELRRRFKLPVTIDAWMSKKLHLLSECVGYTIPEDTPYDPMQNLRSLRKHYPDCGL
YLALLGFKTQMPVLRQTLA
>A0A3N0CLI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmoricola ginsengisoli|TrEMBL
MSLTTKVSAREGELLLFSLTPPKESTAPAEVDRIAEVTLERLAGLDLDGLILYDIDDESE
RNPEARPFPYLPTLDPAVFYADNLAALDLPVVIYRCVGKYDPADLEGWLAGQDVERVLTV
FVGAASRTTEVRTGLAQAHEVRKATRPELLVGGVAIPERHAGGGDEHLRLIRKQGNGCSF
FISQVVYDVAAAKDLLSDYVYACRDQGSEPVPVVFTLSVCGSYKTLTFLEWLGVQVPRWL
RNELAHSDDTLAVSYEHCVHAAAELAEFARRLRVPFGFNVESVSNRKVEIDASVDLVREV
AQLLRR
>A0A1F9MJV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYA12_FULL_61_11|TrEMBL
MKVIDHLRNNHGPCISFEIIPPLKGQMIRHVYEDIEPLLEFKPRFINVTYHREEYVFKER
EGGLLEKFSIRKRPGTVGICAALMYKYDIDTVPHIICGGFSREETENALIDLHYLGVHNA
LVVRGDPIKTETYFKPHPRGHSHASELLQQIKAMNKGVYLDQDIEDPWATDFCVGVAGYP
EKHFEAPNQAADLRNLARKVELGAEYVITQMCFDADRFLAFVEQCRGLGIEVPILPGIKP
LSSFNQVRSFPTLFHIEIPEALLAELDHCKSNHDVELVGREWAVTQCRKLLAGGVPGLHF
YTMSRSGPTREVLKAIL
>A0A211YRP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrodictium delaneyi|TrEMBL
MIGPMRILGELEPTKNNEKLAKRVEKLAGVVDAIDIPEAPMGKPIAHAAILAAYIKAKYG
IDAIPHVRVSDLNTVGLLSILGGLKATGIEEAVLLKGDQPIVGKEVEELTVESAAEVASS
RLGGKPRLGAMMSLRYPLEAITKRLQAPLDFYLVLRPSHSLEKLEQVSKLAKSLNKRLYT
YVIVASSRNYSKLREMLVGQPVYNIDEAVRFVTKIQGLVDGILISSPGDVDTISETARRI
KKELRLD
>A0A7M3JY78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira meyeri|TrEMBL
MNQILLEVIPRDVQTLLSEVSFVKNNFSQISGINIPDLLRFETRSWVAASKIQNVFPNVI
PHLRAIDFDLDHSGHIIEFLQKNSISSVVVIKGDPPSDMSQKVYPTTSIKLIKKLKKEMS
SLKVYAAVDQYRSGIKDEFDYIEMKIDAGTDGFLTQPFFDLRLIHIFTEKLRGKEVYIGI
SPVTNEKSQSYWESRNRAYFPRDFQLTMDWNVQFAKEVIDYCSKNHFNMYLMPIRIPLET
YLRGIFK
>A0A6L9KSV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrovum sp|TrEMBL
MMESFYKLLDWTLDGMRPLARFIGYERLEKPVAAIERGVKGLLFDCRMCGACVLSANGMA
CPMNCPKAMRNGPCGGVRQNGNCEIAADMPCVWVEGWKGAQHMRDRADPQSPNAPVEYHY
AGKSSWLRVLRQEPWPTSLLTQAPRSVQASSAGGLEALLREGIFVTTSECSPPDSADPAD
VLRLIHHFEDYVDALNVTDAPGAHCHMSSLGVSLILAKAGWEPVMQIACRDRNRIAIQGD
ILSAAALGVHNLLCLTGDGIGNGDDPGAKPVFDLDAVSLLDTARRLRDDGMYRSGRKLVS
RPRMFLGAVDNPFVPPFDLRPMRLAKKITAGAQFVQTQYCFDVLLLEQYMARVRDEGLDR
QCFILVGVGPVVSPRAAHWMRTHVPGVHIPDELIRRLEQAADAEAEGVRICVDTIQRIRA
IKGVAGIHLMASKKEHLIGEIVNASGLRAQRAPPSKSKGGSTCHLQD
>A0A7J5EES5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTEHLKNAKKPLISFEILPPLKGKSIQSIYDSIDPLMEFKPSFINVTYHREEFVYKKR
EKGFLEKIAIKKRPGTVGICAAIMNKYQVDAIPHIICGGFTKEETENALIDLNFLGVDNV
LALRGDPIKTESTFVKEEGGHAYAVDLVKQIVGLNKGIYFDEDLQNANPTNFCIGVAGYP
EKHFESPNQKTDLKHLKAKVDAGAEYIITQLFYDNQKFKNFVESCRAIGIEVPIIPGLKP
ISNKSQLVSLSKFFHIDLPDELVDAIEKCKNDDAVKQVGIEWAIQQSKDLLAFGSPCIHY
YTMGKSVATREIIKQVF
>A0A3B8GZS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVIDHLKDAKRTLFSIEILPPLKGKSIQSIFDGIDPLLEFQPSFIDVTYHREEYVYKKR
EGGYLEKVSIRKRPGTVGICAAIMNRYKIDAVPHIICGGFSKEETENALIDLQFLGIDNV
LALRGDSIKTEPGFVPDPDGHHYALDLVQHIDKMNNGIYLEDDVKDMAPTNFCIGIAGYP
EKHMEAPNMASDIKFLKMKVDAGAEYIVTQMFFDNKKYFEFVDLCRKNGINVPIIPGLKI
LTGKKQLTGLPKIFHIDLPEELYENVEKAKDDKEAKEVGIDWCIRQSKELIAKGVPCLHF
YTMGLSDSTRRVAKEVF
>A0A1G6IJG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostocaceae bacterium R-53105|TrEMBL
MNLKDVFQTKTVFSLEVFPPKSELATQKLLNSLTGIQSIKPDFISITLGAAQMDIQKTVN
LATAIQEQLSIPAMAHLTGLYLSKQQAADTLSILKESQINNILALRGDQVSNCPPVGDFK
YAAELVNFIKCHGDFDIAGACYPQKHPESSDFVADTLHLKEKVNQGASHLITQMIFDNEA
FWQFKERLQLANINVPVEVGIMPCTNHQQIQRITALSGIQMPKKFTNIMARYADNKEAMR
DAGIAYAIDQIVDLVASGVDGIHLYTMNNPENAQRIWEATHTLFEAQNKQLAYPL
>A0A3D0QKZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
PLLEFQPSFIDVTYHREEYVYKKREGGYLEKVSIRKRPGTVGICAAIMNRYKIDAVPHII
CGGFSKEETENALIDLQFLGIDNVLALRGDSIKTEPGFVPDPDGHHYALDLVQHIDKMNN
GIYLEDDVKDMAPTNFCIGIAGYPEKHMEAPNMASDIKFLKMKVDAGAEYIVTQMFFDNK
KYFEFVDLCRKNGINVPIIPGLKILTGKKQLTGLPKIFHIDLPEELYENVEKAKDDKEAK
EVGIDWCIRQSKELIAKGVPCLHFYTMGLSDSTRRVAKEVF
>D0I3V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grimontia hollisae CIP 101886|TrEMBL
MGYSHASHLDALNQNLSDLNGDINVSFEFFPPSSEAMEQTLWASVQRLKTLKPKFVSVTY
GANSGERDRTHGIVKSIKQETGIEAAPHLTCIDASRDELRDIARDYWNSGIRHIVALRGD
LPEKSQKPDMYAADLVELLKGEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIIPGILPVSNFKQASKFANMTNVRIPAWMHKQYD
GLEDDPVTRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPTV
>A3JNS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium HTCC2150|TrEMBL
MHTSLIIILNIMNLFNVRSREIQEPTYIKGRDMTPNVSFEFFPPQSLDASFRLWKTVKDL
APLDPNFVSVTYGAGGTTRKLTHEAVAAINKNYGLKVAAHLTCVDASRTETLKIASAYAA
AGIKDIVALRGDAPKGQNKFIPHKDGFANSVELIAALSETSDFNIRVGAYPDPHPDARGT
DADVEWLKRKIDAGASSAITQFFFEADTFFRFRDKCAAAGIAAPIVPGILPIDSWKKIRG
FAARSGAVIPTWLDEAYEKAMRDDREELLSIALATELCSHLIEGGVEDLHFYTLNKPHLT
REVCHAMGIQAQMTLEKVA
>F2BTC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis SK1057|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFHALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A502CTX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas oligophenolica|TrEMBL
MTISVNQLEEARRALDAPLYADVGGALEVSFEFFPPKTDKMEEQLWGAVRTLEPLAPRFV
SVTYGAGGSTRERTHATVARIQRDTSLAAAAHLTCVEATRDEVDQVAREYWAAGVRHIVA
LRGDMPTAGATFAPHPGGYENAAALVAGLKRLHPFEISVAAYPECHPDSADDAADLDNLK
RKMDAGATRAITQFFHEPDTFFRYRDRLAAAGIDAEIVPGIMPVANFASVVRMSAMCGTD
VPAWMARLFDGLDDRPAARQLVAATIAAELSRKLYAGGVKQLHFYTLNRAELAYAICHLL
GVRATSVATEAAA
>A0A3D8SX11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus mulundensis|TrEMBL
MHIKDKLAQNEAAGKIGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDVTWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQERVDAALQAAYNAGCTNILALRGDPPREKEV
WEAADGGFRYAKDLVKYIRDKYGNHFCIGVGGYPEGADDNSDVDQLIDHLKEKVDAGSTF
IVTQMFYDTDNFIKWVEKCRAKGITVPIIPGIMPIQTYAAFIRRANWTKTLIPPDWLEAL
EPVKNDDAAVKQVGKRLIADMCRRSIAAGIKHLHFYTMNLAQSTQLVLEELELSPTAEAP
IPRPLPWRPSLGLNRREEDVRPIFWRNRQSSYIARTAIWDEFPNGRWTDSRSPAFGELEL
YGVGIKGTNEQNIKLWGEPKSLSDLAHVFVRFLEGSLDRLPWSDSPITPETNAIKDPLVE
LNKRGFFTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLIPPYVIDELIARIDTNE
DLTYHAVTKHGELRTNTRDSPNALTWGIFAGREVVQPTIVETVSFLAWKDEAYQLGEDWA
KCHDAASPSRKLLQGIMDSWYLVNIVNNDFHNTYDLFELFKDLNVKDLDVEIPGETTEQK
AHQNGTTNGSNGTTNGITSNGTAAEAVKN
>A0A2E2Y5F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKITDILSNAKGCEFTFEILPPLKGQKAQEIFDHIDPLMEFKPPFIDVTYHREETVYKRL
ANGLLQEKVVRKRPGTVGICAALMHRYQTEAVPHVLCGGFTKEDTENVLIDLNFLGIENI
VALRGDQAKGESYFTPKPDGNKYAIDLVKQIFDLNQGNYLDEELENTMKTDFCIGVAGYP
EKHFQAPSLNIDIENLKDKVNAGADYIVTQLFFDNSKFFAFVDKCREAGITVPIVPGLKP
LVTKRQLSILPQIFHVDIPDTLAMEVLKCKDNTQVRRVGIDWCIQQSKELMAAGVPVLHY
YSMGKSKNIYEIAREIF
>B9L045|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2)|TrEMBL
MKHPFRDRIEQGVLLADGAMGTQLYERGIRLDRCFESANLTHPQLVVEIHRAYILAGAEL
IETNTFGANRFKLEAYGMAERVREINRRAVRHAREAREICGVPVFIAGAIGPSGRLLAPV
GTVAPESLRPVFREQIEALLEGGVDLLIFETMSQLAEIREAIMAAREVCDLPIVAQMTFA
ADGRTIAGHGPEEVVAALAELGVDVIGVNCSVGPRPTLEVLRAMIAANRWGTALSAMPNA
GWPTVVGHRVIYGASPEYFADFAREAASLGVRLIGGCCGTTPEHIAAMRRALDDIKGQVR
PAVEVRARVSTPVMDAVAPEEPTRLRQKLGREFVVSVEIDPPKGLNPSKAIEGARLLRQV
GVEFINVADSPMARVRMSALALCVILQQETGVETILHLTTRDRNLMGLQADLLGAHALGV
RNILALTGDPPTLGDYPHATPVYDLDSIGLVRLLQNFRQGFDAGGASIGRPAMFTIGVAC
DPTRPDLQQEIERLHAKLAAGADFVMTQPVFDFSTWRNFVAQYEIRYGPIEVPVLLGVLP
LQSFRHASFLHNEVPGITLTEEALERMRRAGPNGRAEGVAMARELIAEACEFVQGIYLMP
SFGRYEVVAEVLSALPERLRVSTR
>A0A2D3C8W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus portucalensis|TrEMBL
MPSAFKEKLLSDEFIVTSEISPPKGVDASSAFEEAGLVRDYVDAFNVTDNQRAVMRMSPL
AMGHLLKEQGLDIIMQFTCRDRNRLALQSDLLGAYAMGMENVCIMSGDYPTKGDNPGAKP
VYDLDSVQLLGAMNRLEEGFDIAGNPLESVPSFTKGAVCNTEPDQPLQLMKLEKKARMGI
DFFQTQAVYDIGHFETFMESISHIEVPVLAGLIPLKSAHMARFMNEKIPGIRVDDELIAR
MESSTDPAEEGLLICAEQIRELKKVCRGIHLMPIGHYRHITDLFEMAGLHEKN
>A0A7H2RV99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKTQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A5R8ZA85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mosselii|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKAELRALLEQYKAAGIQRIVALRGDLPSGMGMASGELRYASDL
VEFIRQESADHFHLEVAAYPEMHPQARHFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRLCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A142L1W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium UKL13-3|TrEMBL
MKVTEHIKNAKSTLFSIEILPPLKGKDIQSIFDGIDPLMEYKPAFVDVTYHREEFVLRKR
KDGGFDKVFTRKRPGTVAICAALMNRYKIDTVPHLICGGFSKEETENALIDLNFLGIDNV
LVLRGDSIKNEPNFIPEPDGNKTSLELLHQVKNMNNGIYLDEEISNATPSNFCIGVSGYP
EKHFESPNMNSDLRWLKQKIDNGADYIVTQMFFDNKRFFEFLDQCKKMGIDKPIIPGLKP
LTTKKQLTVLSKLFHIDFPEELVLEVEKCKDDKAVKQIGIEWAIQQSLELKNASIPVLHY
YTMGLSEATKAIASKVF
>A0A164ZQU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Synechococcus spongiarum|TrEMBL
MKSQFSPSAFQQALASGQPVVTAEISPPRGGSVDHVLATAEQLRGRVHALNVTDGSRAVM
GMSSVAVCRLLLERNLEPVLQVGCRDRNRIALQADLLGAHALGLHNVLCLTGDPVKAGDQ
PKARPVFDYEAVRLLQDVKNLNRGLDALEQPLPDGPTALFPGCAADPQSPSWSGLKSRLQ
RKKEAGAQFIQTQMVTDLAALRRFCRELAAPLDLPVLAGVFLLKSGKNARFINRMVPGAS
IPDGAIARLDRARSPRAEGLRMAAEQVAAALDVAQGVHIMAIKAESVIPQILDLAGVPPL
TPPVVDGVGLRSLAAELR
>A0A1I1ZSQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. yr596|TrEMBL
MYPTAFRPSRESRRPIRVSFEFFPPKTPEMEATLWSSIERLAPLGPSFVSVTYGAGGSTR
ERTHNTVSRLVRETELKPAAHLTCVAATKGEVDDVVRAYHEAGVRHIVALRGDPADGVGT
AYTAHPGGYERSCDLVAGIKRIGDFEVSVSAYPERHPEAGSLDQDLDALKAKVDCGADRA
ISQFFFDNDLFFRYLDRVQSRGIDIPIIPGILPVQNFKQAANFARRTGASVPDWLAARFE
GLEDDVATRKLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRAAPAAAE
KAAA
>A0A562CBM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas sp. J16|TrEMBL
MTAISFEFFPPKTDEQRAQLDRTVAKLRPYRPEFVSCTFGAGGSTLTYTSGTVRHLLREH
GLDAAPHLSCVGGSCDEIAALLDEYRELGCRRIVALRGDLPSGMGQPGELRYASDLVAFI
RKRHGDHFRIEVAAYPETHPQADDALADLRHFRAKVAAGADSAITQYFYNADAYFHFVDA
VRALGVDVPIVPGIMPISNFSQLRRFSAQCGAEIPRWVEKKMQALGDDVDAIREFGADLV
AKLCRRLLDGGAPALHFYTLNLARPTQAVLARLQ
>A0A4Q9FMA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyunsoonleella pacifica|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPKKGKNIQDLYNNIDPLMEFKPPFIDVTTSREEYVYID
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKDEPYFKPIKGGNAFASDLVQQIADLNRGKYLHDDVEVEHNSDFCIGVAGY
PEKHMEAPSLLTDLKRLKAKVDAGADYVVTQMFFDNKKYFEFVEKAREMGINVPIIPGIK
PIAVKRHLQLLPQVFKIDLPQDLIDAVEDCKDNKAVRQVGIEFAIQQSKELLDFGVPVLH
YYSMGKSDNVHAIAKALF
>A0A562GQQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa sp. KB1|TrEMBL
MVLKDKLGKSFVYTTELGGINGTNIEESITKVKEYSGLDALNIHDCPNARLRMNSVMAAA
VISRATGMETIPHFTCRDRSLLGTQADLLGAHALGIRYLLPTTGDGPQHGPYQSTAVYDY
NSASLIELIKGFNQGKDANGEVFQGQTQFTVAATATPGAVNLDAEMANMLKKSNAGADFF
QTQPVYDAEQTLRFLAKAKALGKPILLGLMPLKSLKMAEFVNKNVAGITIPPNILAEMQQ
GKTGFEVACEFISQIYQQIDGLHIMGMGDVAVTNKLIAFTRELQSQR
>A0A1M3L721|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|'Candidatus Kapabacteria' thiocyanatum|TrEMBL
MAIELAKRGFSERPCDRYNLAHPVVIERIYHEFLDAGATLLQSNTMHSNRYALESSMLSA
RVHELNRKGVWIARTAAGDRAVVAGVVGPAGRFLRPLGPLEPDDLRACFTEQVTALLAAG
ADIVMLKSFINLDELEIAIDVVRALSTDVPLVASKSFPEDGSVLASSYPSDVAERLTRHG
ITALGSNGTVGPQRMLAIVQSLRVSPVALCAQPDIGIPTIIDGFPVYNAEPQYVASAAAR
LVEHGAAIIGADGGATVEHIRAIADAVRNHGVGTAPVVIKHAPKEHGRDAAEDSRSTFQR
TLGNGFVATVELDIPRGLDMHSVIDGARYLKAHGIDAVNISDGARARLRMSPIAISHMVQ
TQTGMECITHLACRDRNMVGLQAEVLGAYALGLRNILAVTGDPTHIGDFPSATSVYDVDS
IGLVRAMGRMNHGQDLMGNPLGEPTQFCIACAVNPAAEDLEREIDRLAAKAEEGAHVAFS
QPIFDEELLHTFLERIQGIDIRFMLGVIPLRTIRHAEFLHYEVPGMAIPVWVRERMRAAG
TDTEHATAVGIDITVEFLRSVMNRIDGIYLMPPFKKYDIAVRILEQVQPSKVNRAAG
>K4ZF18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus alvei (strain ATCC 6344 / DSM 29 / NBRC 3343 / NCIMB 9371 / NCTC 6352)|TrEMBL
MRDRMKNFREALREQIIIGDGAMGTYLYQLGYPVGISYEILNVSDPDVVRNIHKQYVDAG
AQLLETNTFTANREKLYRHGKEHLVKDINRAAVRLAREAAEDRAYVIGALGSIRAGKREN
VHTNQVIRDYHEQLSAMLEEGVDGIMFETFYDLEEMRLALQVVRELDHDVPVICQFAVEE
SRRTKDGKSLLEAFRVLRDDGADVVGLNCHMGPNGVLRALEGVQGRIDLPLSAFPNAGLP
DYVDGRYNFVATAEYMAQSAVQFVQMGARIIGGCCGTTPEHVAAIVEALHDVEVPELPVQ
PAESIGIEEEAESLHWPDGAACFDGCGHGHDAEESIVDMVRSRHTVIVELDPPRDLDISK
FMKGAQILKEAGVDALTLADNSLAVTRMSNMALGYMALDKIGIRPLVHIACRDRNLIGTQ
SHMMGLHALGIDHVLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNSGLAFSGKPLK
QKANFVVGGAFNPNVKHLDKAIARLERKVEAGADYIMTQPVYDVGLIERIAEGTKHLDVP
VFIGIMPLASGRNAEYLHNEVPGIQLSDDVRRRMNGLEGEAGRKEGVAIAKELLDVALTH
FKGIYFMTPFMFYEMTAELTQYVWEKAERQADPLYRLT
>A0A5B8G140|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paroceanicella profunda|TrEMBL
MTDPTLAGPRQTISFEFFPPHSPEASLRLWRSVERLAPLGPSFVSVTYGAGGTTRERTMA
AILAIRDRARLDVAGHLTCVGASRAETLEVARGYAKLGARSVVALRGDPPKGAERFVPHP
EGFTSAAELVAGLAADGVQNIYVAAYPEVHPEAASPEADIDNLKRKLDAGATAALSQFFF
DTELFLRFRDRCLAAGITAPVHPGILPVENFDRLVNFAGRCGASVPEFMHRAFGNAGTAE
DKALLATAIATDQCDRLRTEGVEHFHFYTLNNPDLTFDICRAIGVEAQPLSMAAHGGR
>A0A8H3APZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKLSEKLANHASDVPYFTFEFFPPRTEQGYSNLLTRITGLAGLKPIAASVTWGAGGSTRD
RSLDLAGFCQTENGLDTILHLTCTNMEQGTIDDALTTAMDKGISNVLALRGDPPRGEEYW
IPTDPRFRHAEDLVTYIRQHPKFGSHFCVGVAGYPDGHSEGGNEEEQLAHLKRKVDAGAE
FIITQLFYDVDKFKLWLRKVRNAGITIPIIPGMMPLQTYATFTRMTDLCNATVPQHIQAN
LDAIKHDDQLVKEYGASLAVSMIRSILSDGDVKGVHFCTLNLEKSVRKILDELGWTHGTH
HPNQIITDASHSPHILPAPADAPNPVTFTISPSEATQHAAISLAEHTRTGTVRTAAEAIS
SGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPPHVAISQWGRPTTEKDLSDLFLAYLNN
KNSTTPFSPTPLSDESTTILPSLVSLTSKGLWTVASQPAVDGALSGDPVVGWGPRDGRVF
QKSFVEFFTTEEELVKIAKAIEDSGDGWVTFFAGNNDDGFVSNIPDSGSNAVTWGVFPGQ
EIAQPTIIDRDSFLAWKDDAFMIWHDFGLCYPPDSPARKLLEAVAKTRWLVSIVHHDYKD
PNALWDFLAKYLN
>A0A7H8UX34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mannheimia pernigra|TrEMBL
MNYATQIDALNQHIADIGRKINVSFEFFPPKNEKMETLLWDSIGCLSPLKPKFVSVTYGA
NSGERDRTHSIVKSIQEKTGIISAPHLTGIDATPEELKVIAKDYWHSGIRRIVALRGDVP
QGYDKALFYASDLVALLKSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVSIGIDCEIVPGILPVTNFKQLKKMATVTNVKIPVWMGKIYEGL
DNDQTTRNLVAASIAMDMVKVLSREGVNDFHFYTLNRSELTYAICHTLGIRPE
>A0A2D5HMJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MLTENPINIIKNIAKNWSIEITPNAAKKIDDFSKILRKKTIVNVTFLPNTNFLETIEVSR
RLNESGMSPVPHISARAIRNTNELDYFVKSLTESCGVNEVLVIAGSSSSPADKFHETMQI
LNSGILEKYNIQKVGVAGHPEGSPDISDDLINASLKRKYEWSLKTGIPIYIETQFLFEAE
PVLDWEKNIRDQGMKIPVRIGVPGPATIKTLFQFAKSSGIGPSMRMITKQAKNISKLFIV
QAPDKYIYDLSFGVYNDKECNIEHLHFYPFGGFKKTALWAANLEKGEFSPNDKGGFKIHE
S
>A0A1F6UYX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Muproteobacteria bacterium RBG_16_60_9|TrEMBL
YETVKQLTARGVRVAPHLSCVGATRATLTDQLRAYQALGIKHIVALGGDLPSGMAAPGDF
RHAYQLVELIRAETGDHFHVEVAAYPEVHPRAQSREDDLRQFKRKIDSGADSAITQYFYN
ADGYFRFVDECEVIGLDIPIVPGIMPITNYKQLARFSDNCGAEVPRWIRKRLEDFGDDIE
SIRAFGLDVVTELCTRLLAVGAPGLHFYTLNRAGPSDAIWQRLKL
>A0A1Y3ZBL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides johnsonii|TrEMBL
MKVIDLINSSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQKTDIYHEHATDLQQQVNDFNKGIAIDGSAFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDDEAKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVYKVAKEVY
>A0A420BT93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia kunjamensis|TrEMBL
MTQLPDSDPTDGGRHPSIVERIATSTTPRVPFSVEFYPPRDEAAEERLWRAATVFSDLGA
AFVSVTYGAGGSTRDRTVRVVERLVRETDLLPIAHLTAVDHTVAELTDMIRMYGEVGVSN
ILALRGDPPGDPLGEWTAHPEGLYYAEELVRLIHEVGDFHVGVASFPEGHYRARDLEHDS
EILVNKLRAGAEYSITQMFWDVEHYLRLRDRAVAADPEQGAKPIIPGLMPVTSLRQVQRM
VELSGCALPDDLAERLRTAAGDGPEENRAAVREVGIDLTTRMCERLIAEGVPCLHFNTLN
FSKATHEVLTNLSMAPAPGVAAGRI
>A0A438ALN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesobaculum littorinae|TrEMBL
MTRISFEFFPPRSLDASFRLWETVRTLAPLGPDFVSVTYGAGGTTRDLTHDAVETIRRNW
GLEVAAHLTCVGATRRETLAVARRYAKAGLRQIVALRGDAPKGSAGFTAHPDGFADSTAL
IEALAETGDFHIRVGAYPDPHPEAAFDGADIAWLKRKFEAGAGSAITQFFFEAETFLRFR
DACQRAGIDRPVIPGILPIANWDGVRRFAERAGTPVPPWVAQAFANAQRDGTERLLATAI
AAELVSDLRDEGVEDFHFYTLNAPELTRDVVRAMGIVPAQALERVA
>A0A1X1QNN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cycloclasticus sp. symbiont of Bathymodiolus heckerae|TrEMBL
MALEPHQPISFEFFPPKTEEGREKLLKVSQTLGKISPAYFSVTFGAGGSTQQGTINTVLD
LKKQGFSAAPHLSCVGSTKENIREMLANYKQEGIDRIVALRGDIPSGTLDIGEFRYANEL
VGFIREETGDYFHIEVAAYPEIHPQAKNAQTDMANFKQKVEAGANSAITQYFFNFEAYIR
FVEDCDKMGLTVPIVPGVMPITNYSQLARFSDMCGAEIPRWIAKRLEGFGDDRESIKAFG
TDVVSELCQSLLDYGCPGLHFYSMNQAEASLAICRNLGVENA
>A0A0P1HKW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leisingera aquaemixtae|TrEMBL
MMDLSLPQPYSPPPEGHVSHSRLERVLRSGRFAITAELNPPDSADPADVYDAARPLGEVA
DAINATDASGANCHMSSIGISALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAAMGVSNV
LCLTGDGVGVGDQPGAKPVFDFDSLSLLRTIRTMRDERKFLSGRTITNPPLLFLGAAENP
CIPPYEWRPERLAKKVEAGAEYIQTNYIYDVPLFEKFMARVRDMGLDKKVFILAGVGPLA
SARAARWMRSNVPGIHIPDAVIDRMEKADKPGQEGKKICVELIQQMREIAGVSGVHVMAY
RKEHQVSEIIQESGVLASRKRT
>A0A1Z9VYW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. TMED90|TrEMBL
MSSALQRSLEAGSITITAEVMPPRGGDPAHTIAMAECLRGRVHAINVTDGSRAVMRMCSL
AVCRLLLDVGLEPVLQMAGRDRNRIALQGDLLGAHALGIRNVLCLTGDPVRAGDQSSVRS
VHELESVRLLQQVSAFNRGEDPVKERLADGPTNLFAGTAADPHCASWSGLSRRLSRKREA
GARFVQTQMVMDPRALERFCRHLADPLELPVLAGVFLLKSARNARFINRMVPGACIPDHL
IERLEKAKDPMVEGIAIAAEQVRQFTGIAQGVHLMAVKAEQRIPEVLDRAGVSLPVL
>A0A2E3R5N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp|TrEMBL
MRVCDLIDKKSPFISLEFFPPKEKDAWPGFFDVVEKLKELAPLFASVTYGAGGGTQDNTL
EIATRMKRDHGIEPITHLTSVGASAKRLDDFLLKLREANIENVLALRGDPPRGVEDFDFD
KQEFRHATDVIEFISKRYPEMCVGGAAYPEPHFESPSIQSDLEMVNLKVQKGAKFLVTQL
FFDNRLYFDYVERLKQMGSEVPVIPGILPIMSLKSAKFILSLCGAAIPGKFLSALEKAHE
EGGDEAVYSLGMEYAIKQSQELLDGGAPGVHLYTLNRAKACLDIGRNLKIEERLERE
>A0A2D7MIM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MTDTIDMIAKAGANWSIEVTPPGAAKIEDFSSILAEGTTVNVTFLPGTNPVDTIDVAKRL
RDSGLVPVPHIAARSLKSKDQLAELVADMTSRANIDEVLVIGGGVTQPVGEFASSMEVLK
TGILQSAGIRKIGVSGHPEGSPDIKDNLLADALAWKNEYARKEGLDLYIETQFCFDADAV
IAWEKRIRADGNTLPIRIGIPGPATIKTLFRFAQISGIGPSMRFIAKQARNVTKLLTVQS
PHLLIAGLAEAMANDPDTKLNHFHYYPFGGVAKTAVWASQVASGQVKLLPKGGFQVIEQA
ASKAS
>A0A1B9LUQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVQPKDDF
RYASELVTFIKENGDFNVIGACYPEGHLEAATLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYTFLDKARDIGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPEAF
RDAGIAYAIDQIVDLVSQDVDGIHLYTMNNSYIARRISEAVSTLLAVPKSK
>A0A6P6Y505|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dermatophagoides pteronyssinus|TrEMBL
MFEIAKIDENDNRKYVSLADRIRERSIKQQQYDRFFSVEFFPARTVQGAKNWIKLVENYS
DGDPLYCDITWHSAGNPDSNAPTSSLMMANVALNYCQLETMLHITCIDLTCKQLNQYLQR
AKHYGIRNIMALRGDRHDDDDHQTDNHQFQYAADLVQYIRHHYGEYFTIVVAGYPIPHPE
SQDKQHDRQCLKKKVLIGADYIITQLFFQCEDYVEFVEECRQIGINVPIIPGICAINSFE
SLVKFSKLSAVPIPSELFDRLEQVRSDQQAVQQLGINYLTNLCRQLLATNLFPGIHFYTL
NQSSIIQVIKNCGLWGKCSIIPWRQSQHYKRINESIRPIFWSNRPKSYIHRTRKWTQFPT
TNWSTEFSSNLDSTSLTDFPQYLNFNLSPDTKKRLSECENLQQLYAIFDDFYSSTINQST
TKTTINLDRNNNDIDQNSTRQSLRRLSLPWINVVNDQYIESLYQKYGQFISKGLMVTNYL
PAINGYNNDKIIYTCKNEKNSYIYHQKEYIEFFIHIRHLSLLQSWLLDKDYQHEISFMAC
NEDKSIRLTNWSSTEQEQHQQLPLVIAWLRLSNTDQLRQRRRPVYIADMKTFDVWLNETY
SLWNELINETPTLIINGSINEQNETNNNNKKVLAHVRNELILVCMIDNRYGHSSSSSSSS
FSQLFAHIFSQ
>I0T7D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis SK579|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIIFALQNMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDEVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3A1XY59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium NR016|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGINAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQESAGVFEHASDL
VYYIRSKHPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNADCLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A3S1V2N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.13.1.1|TrEMBL
MNDMRQELIQTRGSATFAFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLATAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLEICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWLRVNER
>A0A1W9UUF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium 4572_32.2|TrEMBL
MIAGSNLEKVLRAGHFAVTGELGPPTNADKSIIDEKAEHLRGVVDAVNITDNQTAVVRMS
SIAVAAMLIEKGLEPVVQMTARDRNRIAIQSDLLGAWALGAKNLLCLTGDHQIFGNHPEA
KGVFDMDSIQMLAMMRDMHEKGIIQSGDDIDVPPTFFLGAAANPFAPPYEYRPYRLAKKI
QAGAKFIQTQCIYNMPRFKEYMQRAGDMGLLDNVYVMGGVTPLKNVGMAKYMAKSVPGLD
VPEEYIDRMRGATSGIPKENKKARRQALREEGIAICVETIQQLQEIPGMHGVHIMAIEWE
SAVPIIVEKAGLFPRPSV
>A0A4R6N305|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kinneretia asaccharophila|TrEMBL
MTTKTPVSFEFFPPNTPVGAEKLKTVVQELGALAPQYFSVTYGAGGSTREKTLATVTDIA
ASGFEAAPHLSCVGATRENIAEILATYRAQNIRRIVALRGDLPSGTATAGEFRYAAELVR
FIRETQGPDWKIEVAAYPEYHPQQRYAAKDLQHFADKMRAGATAAITQFFFNPDAYFHFV
DSARKLGVDQPIIPGIMPFHNYARIAQFAQRDGIEIPRWVALKMEGYMDDTASIRAFGLD
VIAQLCERLVAGGVPAIHFYTLNQSALTLELCRRIGLHA
>A0A522Y5Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp|TrEMBL
MVPISFEFYPPKTADQHLQFDRTVSKLRGQRPDYVSVTFGAGGSTLSHTPETIQKLRAGG
LDAAPHITCMGGSREEIRGLLKLYRALGAKRLVALRGDLPSGMVSAGELRYADELVRFIR
EETGEHFHIEVAAYPEMHPQARDSQADLRNFVGKVRAGANGAITQYFYNADAYFRFVDDV
HHAGIDVPIVPGIMPIANFSQLRRFSDLCGAEIPRWIAQRMLAYGDDAESVRAFGAEVVA
QLCRRLMDGGAPSLHFYTLNLSKPTLNVLAHLG
>A0A2G5HH52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cercospora beticola|TrEMBL
MDKLTDKIAALPPDATYFSLEFFPPKTQQGFSNLNARLSRMAHSLRPLFVNVTWGAGGST
SVKSLALAEVTQRELGLTTCLHLTCTNMSRKLIDEALDQAKVLGIRNILALRGDPPRSDE
YRDDSLPDAGEDDSNKDFTWAVDLVRYIRKQYGDYFCVGVAGYPEGHSDQSHPEHQSVEH
DLPYLVEKTAAGADFIMTQLFYDVGAYQKYEKRLREHESGLFKKIPIIPGLMPVQSYQIL
RRTTKLSHAALPQEILKRFEAVKGDDEAVKRVGVDVLSEIVDTMKHSEFAGPRGFHFYTL
NLEKVVTQILERNDLIPPSTPEVELNLENQAVAVEETDDFVIVEDAKKQQHRRKSSMANS
NPRNRVIISHTRASSTSSNRPASAYEAFDDEAGVPKEKINSRANTLAISEGEGALGREAT
WDEFPNGRWGDARSPAYGQIDGYGVSLHVSVPEARKLWGEPKSVEDISACFRRHLEGEID
SMPWSEETLQPETLTIKNELLSLINKGWWTVASQPAVNGIRSTDPVFGWGPRNGFIFQKP
FVEFFIPNDEWQKLQTRLIENPQITYFAGNAKHEFFSNDTDSVNPVTWGTFTGKEIITPT
IIEAVSFKAWCEEAFGIWNEWQRVYKPGSESSKLLERIRKDYWLVSVIHHGFLEPGALWN
DLLDENSNGV
>A0A1F3ZTE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_62_17|TrEMBL
MPYDPIVHAPPVPPPGYKSASGLEHTLRKGWFAVTAELNPPDSADPGDVLAAAEPLKNVV
DAINATDASGANCHMSSMGISSILSRAGLGVVLQISCRDRNRIAIQGDVLGAAAMGVSNV
LCLTGDGVAVGDQPGAKPVFDFDCMSLLRTLRAMRDERKFLSGRRITTPPRVFLGAAENP
CIPPYELRADRLGKKVDAGADFIQTNYIFDIGMFERFMARVRDLGLHERVFILAGVGPLP
SPKQARWLRTHVPGIHIPDSLIRRLEGAASPADEGKKICIELIRQIREIRGVAGVHVMAY
RREHLVGEIIEESGILKERIAAREAERSR
>A0A1J9RBT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diplodia corticola|TrEMBL
MHISQKLYEGQKNGKPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPTFIDVTWGAGGRNS
TLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALREAYNAGCKNILALRGDPPREKEK
WEATAGGFRYAKDLVKYIRDTYGDHFDIGVAGYSEGCEDQDDPDLLLDHLKEKVDAGGTF
IVTQMFYDVDIFLDWAKKVRAKGISVPIVPGIMPINTYAAFMRRATWTKCRVPPDWLEAL
EPVKNDDAEVREIGKHLIATMCRRLMEAGIIHLHFYTMNLAQSTRMVLEELGLTPDMYSP
LEKPLPWRQSLTPGRREENVRPIFWRNRNRSYVVRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNIKLWGMPKTVRDISNLFVRYMEGKLDSLPWSEQPITSEADVLRDNLVN
LNKRGLLTINSQPAVNSAKSTHPVHGWGPSNGYVYQKAYLEVLVSPELIAELITRIERDP
EMTYYAVNKAGDLKTNAPSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEFYRLGEDW
AKCYSSVSPSRYVIEDLMDTWYLVNIVHNDFHIDNGIFALFEGLEVKDLDKEPHVAADSE
TNGHTTTNGAAHTNGDSKISGTVVNGNSTSAVQNGTAN
>A0A1Y2KKI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. LEMMJ01|TrEMBL
MSSTFDASRASRVPFSFELYPPRSESSQEALHETVRRLAAAGPEFLSVTYGAGGSTGGRS
LDVLRFIREHTDVEPLAHLTCVGNTYAGATALIREFLDAGILRFLALRGDPPAGQSEPFL
GDLESAAQLVQLIDRVQAERAPYQESPVPGLPGAALVAPRQKVDIAVAAFPKGHPRATHR
TQDVEALLAKQAAGATFAITQLFFHPDDYLAFVERARAGGVTIPILPGIMPITSPARLAR
VLELTGEDLPSELAIALDVEPTAEGRREIGISWAARLAADVVAGGAPGVHLYAFNQHETV
LTVLAEAGIVPALRH
>A0A7I9L6K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MYNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSVNSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELRA
>A0A5T1PVE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALADIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A1M5TS24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cognatishimia maritima|TrEMBL
MTAPNISFEFFPPKNLEASFRLWDTVQVLAPMQPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLNVAAHLTCVNATKAETLKIADDFAAAGVSDIVALRGDPPKGSGRFEAHPEGFANSI
ELIEALADTGKFNIRVGAYPEAHPDAADQAANINWLKAKFEAGASEALTQFFFEPETFLR
FRDACVKAGIDKPIIPGIQPIENWKGIRNFATRCGATFPTWLQDAFEKAERDGREELLAT
ALCTELCDKLRSEGVDRFHFYTLNRPELTRDVCHALGVVQNAKLEKVA
>A0A3N6MQK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia dinghuensis|TrEMBL
MKPIELSFEFFPPKTQDGVDKLRATRAQLATLKPKFVSVTFGAGGSTQQGTLDTVVDIAK
EGIEAAPHLSCIGSSKESLRDILGQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVAF
IRKETGDAFHIEVAAYPEYHPQARSPRHDLEAFAQKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNYSQLMRFSDMCGAEVPRWIAKRLESFGDDREAIRAFGLDV
VTDLCRRLVDAGVPGLHFYTLNGGAATKAICERLGF
>A0A517XZV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Urbifossiella limnaea|TrEMBL
MHIRDIFAQHRTTFSFEFFPPKTDEASDELFRNIATLQELQPSFVSVTYGAGGSTRDRTH
DLVVRIQKETSLTAVSHLTCVCHSLDEMTAILDRYAASGIKNVLALGGDPPKTVVGYKRE
DDAFQYAEQLVRFIRSRPNAPDRRGFGVGVAGFPEGHPGCPNRLKEMDYLKAKVDAGADY
ICTQLFFDNRDFYDFRERCELAGITVPIVVGIMPIGSKAGMVRMAELALGAKIPAKLLRA
VGRCADDEAVSRVGVSWATEQCADLLHNGVRGIHFYTLNKSDATRQIYSNLGVADSAALR
AG
>A0A0B3BVW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas flexibilis|TrEMBL
MSQERRYSFEFFPPKTEVGHEKLLVTARRLAECRPDFFSCTYGAGGSTREGTLNTVLTLD
RQVGVPTAPHLSCVGDSKAELRALLNTYKDAGIRRIVALRGDLPSGMGLASGELRYANEL
VEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLKNFVRKAQAGADSAITQYFFNADSYFH
FVERAQKQGVDLPIVPGIMPITNYTSLARFSDACGAEIPRWVRKQLEAYGDDVASIQAFG
EQVVTEMCEKLLAGGAPGLHFYALNQAEPSLAIWNNLKLPR
>A0A420AYC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium detergens|TrEMBL
MKIIDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPSEGGHAFATDLLEQVTDMNKGKYLHEDIITSEKTDFCIGVAGY
PEKHFESPNFNTDFKYLKQKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVAACKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLA
>A0A0Q8KP14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. Root172|TrEMBL
MTARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A4S3GLF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. A1499|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGDWVAHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSTDWESDTRHFID
KCRAGADYAITQMFFDPEEYLRLRDRVEAAGCDTPVIPEMMPVTNVRQLDRLPQLSNAVF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHRRA
>A0A2A5YAJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium MED-G06|TrEMBL
MATSIETIQTAASNWSIEVTPTGATKIESFSDCLDAGTTVNVTFLPGTDPADTIAVCERL
HNDGMRPVPHLAARSLRDADQLEELLSAYTSRCGVEEVLCIGGGVDNPVGAFDATMQVLQ
TGLIQKHGIRHIGVAGHPEGSPDISDDEIAEALGAKNELAKAEGLELYIETQFCFEADIV
LDWERRVRAAGNALPIRIGIPGPATIKTLFRFAQISGIGPSMRFISKQAKNVAKLMTVQS
PHLLLTGLAEGMAADEECLIRHFHFYPFGGFARTATYAGAIADGNIKMLPKGGFEVIDG
>L7L735|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia hirsuta DSM 44140 = NBRC 16056|TrEMBL
MRLAHRAALVKAMPTGELNPVAESMFGAAIRRISRVSVVSEHGGQLPVVEAIAQPHSGPV
PFSVEFFPPRTEADEARLWHAVRVFERMNPAFVSLTYGAGGSTRDRTVRIAGELAEATTL
TTVAHLTAVDHSVDELRGLIGSYADRGITNLLALRGDPPGSPMGEWVAHPDGVEYASELV
ELIGSLGDFHTGVASFPEGHHRAPNLAADTGNLVRKLRAGAEYSVTQIFFDVEHYLRLRD
RVVAADPEQGVKPIIPGLMPITSLQSVRRMMELSGSALPDKVADRLAAAAGTGPEEDRAA
VRAVGIDLATEMSERLIAEGAPCLHFCTLNFARATSEVLDRIGVDTRGALVPA
>A0A1Z4IX57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scytonema sp. HK-05|TrEMBL
MLDTINPTALTSFRTAAKTGQFLITAEVTPPKGGNPEHMVRMAATLKGRVHAVNITDGSR
AVLRMCSLAASAILLQNGIEPICQLACRDRNRIGLQADLMGAHALGIYNILALTGDPVKA
GDHPDAKGVFDLEAVRLLQLIQKLNHGVDCNEKPLTDGALDLFPGAAVDPQCASWSGLQS
RFERKLAAGAQFFQSQLITDFERLEKFMDTIAAGCNKPILAGIFLLKSAKNAQFINRCVP
GVNIPDHIIDRLAQAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIVPILDMAGV
GVVS
>A0A246L120|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas pavanii|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAARLKDYSPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIEFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLVEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A8C7NY61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
KFKYFDINGSITPAVGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRHRTESGDHWFS
LEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYATDLVKH
IRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVR
DCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGIEQ
AVSMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHPKRKVED
VRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMW
GEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVNRRGVLT
INSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIV
NVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQWAKLYED
ESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEQPAEQPND
EQSDKEQPGK
>A0A8C3AIA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclopterus lumpus|TrEMBL
MVNQVQRGDGSLRSCKSDSSGLSNSGGESSKESSRCSTPVLEADRSDRLRDKMRRRTESG
DRWFSLEFFPPRTASGAVNLISRFDRMSAGGPLFIDITWHPAGDPGSDKETSSMMIASTA
INYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEEGFNYAT
DLVKHIRSEFEDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITRVIEPIKDNDAAIRN
YGVQQAVEMCRVLLDSGKVPGLHFYTLNREVAIMEVLRQLGLWIEDPRRSLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSTKDA
LLQMWGAELMNEESVYEVFTCYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNK
RGVLTINSQPNINGKPSADPIAGWGPAGGYVFQKAYLEFFTSSENVTALLEVLKKYEPRV
NYHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWQVIDDMFKMLDAPPGPEDGTVSE
>A0A6A6T8I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lophiostoma macrostomum CBS 122681|TrEMBL
MHISQKLAQARSEGKTTFSFEFFPPKTAQGVQNLYDRMDRMHGYGPQFIDVTWGAGGTLS
QLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALKDAYQAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIREKYGNHFDIGVAGYSEGCDDNPDVDQLVDHLKEKVDAGATF
IVTQMFYDVDLFIQWVGKCRAKGIEIPIIPGIMPISTYAAFLRRANWMKVNVPPKWTKAL
EPIKNDDAAVRDVGQVLVAEMCRKLVDAGITHLHFYTMNLEKGTRMVLEELDILPDAESP
QQKPLPWRPSLGLNRRDENVRPIFWRNRNRSYIARTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNIKLWGSPKSIKDISNVFVKYMEGNLEALPWSESAISKEAGAIQQDLVD
LNRRGFLTINSQPAVDSAKSTHPVYGWGPANGYVYQKAYLEVLVSPEHIAEIITRIERNP
EITYYAVNKDGDLKTNNGGEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFFRLGQDW
ANCHPSVSPSRYVIEDIMDTWYLINIVHNDFHVAHGIFPLFDGLEVPDMERELHSNGVTN
GHTNGHANGHANGPSTTNGETVKIGEKTKIDSAVNSVKNVTSALTNGLKLSN
>A0A7G5Z0G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas alpina|TrEMBL
MTASSAIHPAWALAAPAVMTDGYSLEMTAKDIDALRAAAPHIAPETPIAITFLPGESMDA
RIAAAVTVRSLGFEPMPHLSARRIGSLDELAAMVERSTAEAGVQRVFLVAGDPPIPAGPF
ADTMSLLRTGLFERNGIKAVGIAGHPDGHPEMDSDALWAVLAEKRVEIESRGMAPLIVTQ
FGFDAAPFLTWLRELRSRGIDAPVRIGVPGPAGIKTLLRYAAHCGVGASASVMTKYGVSL
TRLLGTAGPDKLVDALARGIGPEHGAVRLHFYPFGGLSRTVEWIGDYSARHAR
>A0A8C7R0W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
MPASFAPSTSVWDLGLVRDNQCLSFWTSEHGTSNSGGESSKESSRSSTPVLAADRTERLR
DKMRRRTESGDHWFSLEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSNKE
TSSMMIASTAVNYCGLESILHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGDPVGADWE
EEEGGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFII
TQLFFRADTFLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEP
IKDNDAAIRNYGIEQTVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRP
LPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLF
YLKSKSSKDALLKMWGEELTSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDELLAPETNL
MMDELDKVNRRGVLTINSQPTINGKPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLL
KVLKKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDE
AFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNP
PEEQPTEQPVEQPAEESPVEDQSPK
>A0A0J6NME0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium sp. LK11|TrEMBL
MTAQSRTFSFEFFPPKTPEGIAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLATVLEI
RSEGHAAAPHLSCIGSTRENIGAILKEYRNNGIRHIVALRGDIPSGMVAAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDINNFVRKVNAGANSAMTQYFFNADAYFRF
IDEAQARGVNIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRQRMQAYYDDSASIRALGL
DVVTELCDRLLQHGAPGLHFYTLNQAGLVSTIWQRLGL
>E3IWZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia inefficax (strain DSM 45817 / CECT 9037 / EuI1c)|TrEMBL
MAHGPCAGVDAEGACEVPGFGACTFLDVRAADWPYARSLGATPPSPNGVATARPHPTVAA
FRAAAATRPVVVADLPAAPLSAASLRASAAMLAGAADACLLGDHGGARVQFPPSYRARLL
ADEGVAAWVGLNCRDRNRVAIEGEIAACLDAGAVAVHCVTGDHPALGHRPDAAAVFDLDS
VDLVALAAAAAARDGGALCSVAHAPATPPTDRRLARLLTKIDAGADVVFVDHCGGAGPVA
DAVGELRAAGFGGLVLACVPVVTSAASAAVVASFAGDRLPAGYLDRITGGTAADWTPGAA
GHSANGSGPNGLTAAEVAEIETAGIAEGTELAERMLEIPGVDGVNLSGGAPPGQEVALAA
AMAEIARRVLGGSGPPSRRRSRPTAARVGTGAPGATGA
>A0A143YMX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus ilyis|TrEMBL
MKIRDMISKGEPTVSFEIFPPKSSYALETVFDTLTELKDLHPDFISVTYGAGGTAQSNTV
EIASRIKKDFGIESIAHLTGCTSTKEGMKRTLASIKDSGIENILALRGDIPQEKLADKNW
KPEYRYASELIDDIKAAGDFSIGAACYPEGHVDSINKVDDLKNLKRKMDHGADFMITQLF
YDNDLFYQFKEKLELVGIEQPVIAGILPVLNIKQVKRIQEISGCNLPPKFLRILDRYAHD
PASLQEAGIAYAVDQIIDLLSSGVDGVHIYTMNKPDATRRIMENISCVRKAVCRKEPQR
>A0A502WNZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-8-4|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A1I3YLW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. NFR04|TrEMBL
MSIVDPMAPPLFADVAGDVAVSFEFFPPKTEKMEETLWSSIETLSPLGPRFVSVTYGAGG
TTRERTHATVSKIARETPLAAAAHLTCVEATREEIDQIAEEYWAAGVRHIVALRGDPPRA
GEKYRTHPGGYENAADLVAGLRRLHPFEISVSAYPECHPDSPSPEADLDNLKRKIDAGAN
RAITQFFFEAETFLRFRDRAAAAGIHAEIVPGIMPVMNYASVVKMSAMCGTDVPAWMEKL
FEGLDEHPSARQLVTATLTAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGLRPRQQP
AVAAA
>A0A355G3P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKVIDILNNGKVNVSCELFPPKQFSQLVGAKQIVRDVAALNPAFISVTYGAGGGTSEH
>A0A1Q5BF93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TSRI0445|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKA
TQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A6G8KS74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus chromogenes|TrEMBL
MSRLLNTLKNNILVADGAMGTILYSEGLDTCPEAYNLTHPEKVERIHRSYIQAGADIIQT
NTYGANFEKLKVFGLEHKVKAIHEAAIDIAKRAAEEDTFILGTIGGFRGVKQGDLSISAI
QYHTEIQVDTLVDGGVDGLLFETYYDLEELLTVIKSTRRKYDIPIIAQLTASNTNYLLDG
TVINDALEQVIQAGANIVGLNCHHGPHHMKNTFTHIALPEHAYLSCYPNASLLDIENDTF
KYSNNATYFGEVAEQLIHEGVRLIGGCCGTTPEHIQHIKRSVRGLKPVHNKKVIPIHKKR
ESITSPSAKLNLKQKVQQQPTIIVELDTPKHLDTQRFFKNIEALDKAGIDAVTLADNSLA
TVRVSNIAAASLIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNEGINTDGDALKSRTHFNIAGGFDPHVRNIDAAVRK
LETKIESGMHYFITQPVFTKEKIIEIYEATQHLNVPIFIGVMPITSYNNALFLHNEVPGI
KMTDDVLERFKAVAGDKAATYELSISICKSLIDTVHKYFNGLYLITPFERVDYSLDLAAY
SKSITSTNQEVIL
>A0A844AXA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenimonas koreensis DSM 17982|TrEMBL
MTLPISLEFFPPKTPEGAAKLRDARKVLYQLKPEFCSVTYGAGGSTQKGTFETVGEILQE
GVDAASHLSCIGATRARVREELANLKAMGVRRLVALRGDMPSGFGIGGEFHYASDLISFI
REETGRDFHIEVACYPEVHPQAKSPESDLQAFATKVHAGADSAITQYFFNADAYFRFVDE
AKKAGVNVPIIPGIMPIASSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASIKSFGLDVV
TDLCERMRAGGAPSMHFYTMNQAGATVEICKRLGV
>A0A533HUJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemella sp|TrEMBL
MRNLLERLEKNVLVADGAMGTALYSNGLESCHEYNNISNPDSVEKIHKAYIEAGADIIQT
NTYAAKKCQLKTYGYEDKFEEINIRAAEIARKAAGENTFVFGTIGAIRGLRECELSLETI
VNETLDQVKVLLSTNKIDALLFETYYDQEEIRAVLTEARKLTDLPIITNISLLEAGITQN
GEKVTDALSTLVNLGADIVGLNCHLGPYHMIKSLKQVPLFAQSYLSAYPNASLLQLTQTI
NGNEYRFRKNSAYFEQSAKLLVEEGVRLIGGCCGTTPEHIRAIKKGIKDLKPVKRKIITP
LPAEEELVRVANNKPTIVDKVKKQVTIIAELDPPKHLNVDKFIEGAKAIDKKNIEAITLA
DNSLASTRICNLAAATLLKEHISTPTLLHLTCRDHNLIGLQSRLMGFDILGINNVLALTG
DPSKLGDFPGATSVYDMTSLKLIPFIKQLNEGLGYNGASLKKTTNFTVAAAYNPNVRDLS
KTKRLVEKKIKAGTDYFITQPIFEAEKIEQLAEFAADYPDTPFFVGIMPITSYNNAVFLH
NEVPGIKLSEEFLAKLEEVKDDKELCQKIALEESKKLLDIALKHFKGIYLITPFFRYDLT
LELIDYVEENKDK
>E3PXX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetoanaerobium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / CCUG 9281 / NCIMB 10654 / HF)|TrEMBL
MGLLKQAFENGEFAVTSEMAPPKGIDFAHLRHCAQLIKGRVHAANVTDFQSAVMRATSLA
TCKVLQEEGIEPVIQITGRDRNRIAIQGEMLSAGLFGIPNMLALTGDHTVVGDHPNAKAV
YDLDVIGILQAAEILKSGKDMAGNELQGTPDFFLGASVTPRFDPVDAQIFKMEKKIAAGA
KFFQTQAVFDIETMRDFREKTKHMDCKIMAGIIPLKSPGMAKFMNSNVPGIFVPDELIDR
LKASAEGIEDKKEKNKAMVMEGIKISGEFIKQLREEGLCDGVHIMAIGAEENVPLILDAA
GL
>A0A1G6Z7K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter soli|TrEMBL
MTKVTEYIRRAEGKTLFSIEIIPPLKGQNINELLNSIEPLMEFNPPFVDVTYHREELIDR
VGPDGTIERIPIRKRPGTVGICARLMERFKVDAVPHVICGGFTKDETEDVLIDLHYLGID
NVLVLRGDAERSAGVFKPKPGGHSYASELVTQVDNMNKGMLLNAETEMSPTDFCIGVAGY
PEMHFEATSFDSDYAALKKKVDLGANYIVTQMFFDNQKYFGFVERCRAEGITVPIIPGLK
PISTKKQLHVLADIFHLEFPLDLVKEVERCASDKEVRQVGVEWGIQQCKELLAYGVPVLH
FYTMGKSDNVSQIARGVF
>A0A1Y5FTP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium 53_120_T64|TrEMBL
MTKDWLLSFEFFPPKTQPGAEKLARTREILAQLAPEYFSVTYGAGGSTRDNTRDIVLETR
AAGLDVMPHLSLAFGDDDANAIKTLLATYRQAGVSRLLALRGDLPNDSDSTRKPIHANEL
VAFIREHFATQFNIQVAAYPEIHPDAKSYQDDIYWLGEKFKAGADGAITQYFFNIDAYWY
FLDQAAKAGIDKPIVPGIMPITNFTNLARFSAGCGAEIPRWMAKKLEQYGDDQASIIAFG
SDMVTQLCERLLEGGAPGLHFYTMNQAQPSLDILSRLGVSAEQN
>A0A285R3E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas guangdongensis|TrEMBL
MIPIIHPNWARAPINMVDGYSLEMTAKDIDSLRAAAPAIAPVTPVAVTFLPGEDAAARVA
AARTVRALGFEPMPHFSARRIRSEREFRDYLAAAVAEAGVQRCFVIAGDPAEPEGPYSDS
SALIESGAFEANGITAIGIGGHPEGHPNMTPDQGWAVLEGKCAAIERRGMAPLIVTQFAF
DGERVLDWVAALRARGIDAPVRLGVPGPAGIRTLLRFAARCGVGASAAVLSKYGISLGAL
LGSAGPDRLVDTLAAGLRAEHGAVRLHFYPFGGIEKTVAWINDYDNAHGSVMGRMTGE
>A0A524RP90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanocapsa feldmannii 277cV|TrEMBL
MLLRQALVEGRPALTAELTPPRGGETSAAMVAAAALRGRVHAVNVTDGSRAVMGMSSMAL
CRLLLDHGIEPVFQLTCRDRNRIALQAELLGAHALGIPNVLCLTGDPVKAGDQPAAKSVF
DFESVRLLRQVRALNAGLDPGGDGRRLPHGPIDLLPGCAADPQSGSWDGLKRRTQRKCEA
GARFAQTQMVTDREALRRFCGEIAGPLGLPVLAGVFLLKSARNAAFINRVVPGAKIPQHT
IDRLAAAPDPGAEGVRIAAEQVREFLGIAQGVHLMAIKAEALVPRILDLAGIAAIA
>A0A096C7B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella melaninogenica DNF00666|TrEMBL
MGNNITDIKQLLNDETDEKHFSFEVLPPLKGNGTASLFRNIDQLKEFNPSFINITTHHSE
FVYHEREDGLLERQCIRRRPGTVAIAAAIQQRYGIPVIPHVICSGATKEDIEYELLDLQF
LGIENLMLLRGDKAREDRFFTPSEGGHSHTTELIEQVNSFNEGIFIDGSTMKHPGRRFMY
GVACYPEKHEEAPNLEQDLRYLKMKQDLGATFAVTQLFYDNEKFYNFVDQARKMGVTIPI
IPGIKPFAKLSQLNVVPKTFHCDIPEELAGLALLCKSDEEARLLGIEWAIRQVKDLYAHG
FNNVHFYTVSAVSSVHEVMKRLVEIGLLQQNSK
>K2S237|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrophomina phaseolina (strain MS6)|TrEMBL
MEKITDKLAALPPDGRYFSLEFFPPKTQMGFANLQNRLERMANALHPLFVTVTWGAGGST
ASKSLELAELTQRQLGLTTCLHLTCTNMSRTLVDDALEQAKALGVRNILALRGDPPRSEE
YREGEADRDNDSNKDFTWAVDLVRYIRKQYGDYFCIGVAAYPEGHSDQSHPDKQDPKFDL
PYLIEKTKAGADFIMTQLFFDINAYEEFEDMLRNDPSGVFKTIPIVPGLMPIQSYQILRR
TTKLSHAKVPAHILERLDAVKSDDEAVKSVGVDILSEIVEEMKKRPNPGPRGFHFYTLNL
EKAVAHIVERCHLIPPVSANENMEEAVTIDDIPVNGDGPGGSLKTKDRRRLSSANMTPHN
RVVVDRPSTSSNKSYEALADEAGVPKDNVMTRANTLAISEGEGALGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHVSIPQAIRLWKYPVTVEDISDIFRRHILGDLEAIPWSEEGLN
PETETIKDQLLELIGKGWWSVASQPAVNGVKSTDSVFGWGPKNGYVFQKPFVEFFLSSAD
WKKLQAKLDELSDVTYFAGNNAGDFMSNDEQSVNPVTWGSFAGKEIVTPTIIESVSFRAW
LEEAFSIWSEWRHIYPPRSATAELLGRIRDDYWLVNIIHHDFVEKDALWRLVLEN
>K2QJU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrophomina phaseolina (strain MS6)|TrEMBL
MHGLGPTFIDITWGAGGRNSTLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALREAY
NAGCKNILALRGDPPREKEKWEATAGGFRYAKDLVKYIRDNYGDHFDIGVAGYSEGCDDQ
DDPNLLLDHLKEKVDAGGTFIVTQMFYDVDIFLDWVKKVRAKGITVPIIPGIMPIHTYAA
FMRRAQWTRCRIPPHWLEALEPVKNDDAEVREIGKHLIATMCRRLMEAGILHLHFYTMNL
AQSTRMVLEELGLTPDVQSPLEKPLPWRQSLAPGRREENVRPIFWRNRNRSYVVRTQDWD
EFPNGRWGDSRSPAFGELDAYGIGLKGTNEQNIKLWGQPRSVRDIANLFVRYMEGKVDSL
PWSEQPITAEADVLKNDLVALNQRGLLTINSQPAVNSAKSSDPVYGWGPRNGYVYQKAYL
EVLVSPELIAELITRIERDPEMTYYAVNKAGDLKTNAPSDGPNAVTWGVFPGKEIVQPTI
VETISFLAWKDEFFRLGEDWAKCYTAASPSRYVIEDLMDTWYLVNIVHNDFHVSNGIFAL
FDGLEVKDIDKELHGSVAGTEEASTNGHSNGTSHTNGEAKVPDTVVNGNSASAVQNGAVK
N
>A0A084AJI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stachybotrys chartarum (strain CBS 109288 / IBT 7711)|TrEMBL
MDKITDKIAALPAGGSYFSLEFFPPKTAMGFSNLRVRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQRELGLTTCLHLTCTNMSPRLIDKALEDAKALGIRNILALRGDPPRNDE
YRDPDEDLDDGRERFTWAVDLVKYIRETHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVDKVQAGADFIMTQLFFDIEAYDKFEKILREHPSGAFKTMPIIPGLMPIQSYQMIKRT
TKLSHAKVPESIMARLDAVKGDDEKVKEVGVDILSELVEQIKEVKSRSPGPQGFHFYTLN
LEKAVSFILERSNLIPDPADNEEALVDDETAGPRITVNGSEPPSKHTHSRTSRRHSSVGS
DPHDRVIVESRNPAHPEWEVSGQEAGIPAGGINSRANTLAISEGEGALGREATWDDFPNG
RFGDARSPAYGEIDGYGVSLHMSVTQATRIWGYPETPQDINQLFVKHIRGELTAIPWSEE
ELLAESSSIKPHLTNLNSKGWWTVASQPAVNGLPSSDQTFGWGPGNGFVFQKAFVEFFLP
SAEWATLQEKLRSPDVKDHVCFYAANAAGNFVSSDASGNASGDHAESSTNAVTWGVFPGK
EIVTPTIIEEVSFRAWAEEAFGIWGEWAKVYRRDSGSEKLLNGIKADYWLVNVIHHDYIE
KNALWDLLMQ
>A0A1V6HWH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium ADurb.Bin051|TrEMBL
MKVTEHLARATEPLLSFEIIPPLRGGNVQSLLALIDDLQPFRPPFIDITSHAAEVVYEET
PQGIQRRVKRKRPGTLGVCALIQNKYGIDAVPHVLCTGFTREETEDFLIELRYLGIDNVL
AVRGDENGYQKPLKHGRSANHHAVELVQQITAMNQGRYLADDLLDAHPSDFCVGVAGYPE
KHFEAPNPTTDLRHLKAKVDAGAEYVVTQMFFDNRRFFAFVDACRAAGITVPIIPGLKVL
TSRRHLTSIPRNFFVDIPSELADEIAAAPDDEIAEIGALWTVRQTEELLAAGVPALHFFV
MQSSHAIKKVMARLGSR
>A0A077LG24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. StFLB209|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLNVAHQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDTKTELRELLTQYKNAGVKRIVALRGDLPSGMGMASGELRYASDL
VSFIREETGDHFHIEVAAYPEMHPQARNFDDDIAHFVTKVKAGADSAITQYFFSADCYFY
FMERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYSDDTASIQAFG
EQVVTEMSERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>R8BDU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeoacremonium minimum (strain UCR-PA7)|TrEMBL
MHIRDMIADAERTGQPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRVA
ELTCEMVVQAQTYFGLETCMHLTCTDMGLEKVNDALQKAYKAGCTNILALRGDPPREKEK
WVATDGDFQYARDLVGHIRKTYGDHFDIGVAGYPEGTDDNKDEELLLDHLKEKVDMGASF
IVTQMFYDVDNFLRWVGKVRERGITIPIIPGIMPIATYASFLRRANHMKCNVPKEWMEAL
DHVKNDDVAVRDIGKTLVAEMCRKILQAGIRHLHFYTMNLAQATRMVLEELKWMPSVERP
LKQALPWKQSLGFGRRDEDVRPIFWRNRNKSYVTRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSISDVASLFVKYLNNELDCLPWSESPLTSEADSIRNDLIE
LNKRGLITINSQPAVNGVKSSHPIHGWGPPNGYVYQKSYLEVLVSPEILPELIARIEKQP
DLSYYAVTRKGNLQSNAPHEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGLEW
ARCYDAGTPSRVLLEDVMDHWYLVNIVNNDFHQSRTIFELFDGLAVKDLDKVAETNGQVE
PQPNGA
>A0A3F3PY53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus welwitschiae|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVEQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPRSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A395Y5F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. OF02-10|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>R6FYP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium hallii CAG:12|TrEMBL
MNIREYLENHKLLTDGAMGTYFDSIEKENYICSEEANITNPALVREIHRSYVKNGAQLLR
SNTFLANEGTFLSLTQAKAEAFENITLKQLIIAGYQLAKETAQEVYQEEYPIFAAADIGP
ILEERDSEEADILQQYYEICDSFLEAGADIFVLETFPDTQYVLKMAEYIRKSCPEAFIIG
QFSLTPTGYSRTGFHYKTILQEATQSGLLDGAGLNCGVGAAHMKKFLKSYIEEFGVPEDM
VLTSLPNCGYPQIVRGHAVYSDSVPYFGEKLGEISELGVQVLGGCCGTTPEYIGEIYKTV
FQAKKTEGAVKIPTKIVWGDVTKRVQKRKEAAVHITQAGEQKEAIKEKQVTNTFRQKLEM
GELVCAVELDPPFDTDDTKLLNGAKALLSTKADIITIADSPLARSRADASLMAAKIKMTT
GMDVMPHLSCRDKNRIAIRSGLLGSYASGIRNYLFVTGDPVAREDREFTKSVFDFNSIRL
MKFAQSMNQEVFKDDTIFYGGALNQNGASPENIAGRMLKKMEAGCRYFLTQPVYDKEGIE
RLTFLKERTGAKILIGIMPLVSRRNALFIKNEMPGIHVPDEVVAKYKEGASREEFEEAAI
EISKQIIEMGKGIGAGFYFMTPFNRVSLVKSILEYV
>A0A807C7M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium loti NZP2037|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVCRILNETSLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A7X7YGV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Holophagae bacterium|TrEMBL
MLSRVEARFDDHVVVSDGATGSELLAMLPSHGHLDLAALEHPREVLAVHLSYLAAGAELL
LTATFAASRPRLERLQAGDRVEIVNLEAVKLARDAREIAGVDALVGGSIGPLAGVIDLDD
PAGRATIAAAHAEQAASLAGRGADLLVLETFFRLDELELAIRAVREVSSLPIIASLTFPD
ESAPENVAANAEKVRRLLEADLLAAGVNCAPGPHATLEVLDALGEVGGRLAVRPNAGALV
RRAGRLIPPPATPAYLAAFARRAAALGAHLVGGCCGTGPEHIRAIAEAVKGLRPGRRARP
RVQVAERPRPQAPPVAERSSLAAKLAAGVHVHVVQLDPPKGSNADRLVAATHRLAAQAQV
DAFDVNSNPLARLRMDSLWLASEIQRATRIETIPHITPRDASLMGLQSQLLGAWRSGLRN
VLAISGDPSQLGDYPGVHDVYHVDIFELVRALSRMAEGVDCAGNPVGDPPAFCLGVAVNP
GADDLEAEIARLHRKADAGAHFAMSQVFFDWAPWERLLERCGGRLPIPGLVAVWPLGSLK
LALRLHNEVPGIVVPESFLRQLESAGPDAAKVGAELAHRMAAEAPRYAAGAYYVAPFRNP
EEILPFLPPAAHPPKG
>A0A4R9ZCC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.205.01.1.1|TrEMBL
MTARQLDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREVRRDDQIVAERLEHILHDEVTETQVDMVK
TAH
>J2TBF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM55|TrEMBL
MSQERRYSFEFFPTKTDAGQEKLLATARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGNHFHIEVAAYPEMHPQARNFEEDVANFVRKANAGADSAITQYFFNADCYFY
FVERVQALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWKNLKLPR
>B9NZM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus str. MIT 9202|TrEMBL
MKSKLQQTLEKKSKVITAELMPPRGGNPIRSLNIAQLLKDKVNAVNITDGSRAVMRMCSL
AMSKLLLENGIEPVMQISCRDRNKIALQSDILGANALGIRNILCITGDSVKAGDQKDAKA
VHEFESVKLLQQIQAFNKGIDPTLGELSDKKTFIFAGAAADPSCRNLRSLENRMRKKKEA
GAGFIQTQMVMEKQNLIEFCEKISNPLEIPVIAGVFLLKSYKNALFINKYVPGANIPENI
LNRLKDAKNPLQEGIEIAAEQAHDFMNIASGVHLMAVRAEHLIPDIIKKANLSLEY
>A0A416BQA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF41-9|TrEMBL
MKLSEAMKEKMLLSFEVFPPKTEKGMENLPGTIEHLMKYKPEYISCTYGAGGGNVGANRE
VCQMIKKAGTTPVTHFTVIKNTKEGIKDQLQQYLDEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRNEFGDKFEIAVAGSPEGHIACRSLDADIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDMSATINMALSRNGCVMDSELCRLISRNWLFPN
PFAAKDADGKPFDMFYDDKVKRFKEEGIEYTIKQIDEYRAMGVDGIHLYALNKWKDVSEI
IDRSGLRTLV
>A0A0P6VHD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecomicrobium hirschii|TrEMBL
MNPRLHPEDFGENPWDPLPALPGHTSRGRLERVLRRGEFAVTAELNPPDSALAEDVYKRA
AVFEGWVDAINATDGSGANCHMSSIAICALLTRIGFSPVLQISCRDTNRIGIQGNVLGAS
ALGVNNVLCLTGDGVQSGDHPEAKPVFDLDSTSLLATIRRMRDEAKFLSGRKITTPPPVF
MGAAENPFAPPYDFRPLRLAKKVRAGAQFIQTQYCFDVPLLERFMAKVRDMELEKHCFIL
VGVGPLASAKTARWMRSNVAGVHIPDAIIERLEKAKDQKAEGKRICVEIIQQVREIAGVA
GVHVMAYRQEEYVAEMVHESGVLKGRQPWRRDLTRPGFDLDQRLTENLARAGEG
>A0A0P9Q4Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas ficuserectae|TrEMBL
KSAPTKYVFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYG
AGGSTRDRTLNTVLQLENEIKVPAAPHLSCVGDSKDDLHNLLAQYKDAGIKRIVALRGDL
PSGMGMASGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAG
ADSAITQYFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIR
KQLEAYGDDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>Q7MH66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio vulnificus (strain YJ016)|TrEMBL
MTLNRIQYILWTYRRLNVDLRIEIYFVAKGHRESKMGYTHASHIDALNQNIAELSDNINV
SFEFFPPSTPQMEETLWNSVHRLKTLQPKFVSVTYGANSGERDRTHSIIKEIKAQTGLVA
APHLTCIDASREELINIANDYWANGIKNIVALRGDIPPGGGAPDMYASDLVTLLKSLHDF
DISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVAAGIDV
EIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFEGLDDDPVTRQLVGASQAIDMVRILS
REGVKDFHFYTLNRAEMTYALCHTLGVRPKKA
>A0A158IQG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia terrestris|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRASRAHLAQLSPKFVSVTFGAGGSTQQGTLDTVLEMQK
EGFEAAPHLSCIGSSKDSLRTILGAYREHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFNIEVAAYPEYHPQARSPKSDLDNFVRKVQAGANSAITQYFYNGDAYFRFLD
EARKLGVDVPIVPGVMPITNFTQLMRFSEMCGAEVPKWIARRLESYGDDREAIRAFGLDV
VTNLCRRLVDEGAPGLHFYTLNGAAATKTICERLNLKSV
>A0A4Y1ZDK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporolactobacillus inulinus|TrEMBL
MNGRSVFVEFDTPRHLNTDHFFRGVQALEAAGADAITMADNSLASPRISNAAIGKLIKDR
YHMPPLVHLTCRDRNLIGLQSHLLGLDVLGLHDLLVITGDPTKIGDFPGATSVYDVSSME
LIKLIKQFNRGISYSGKSLKKPTHFRVAAAFNPNVRNLDRAVQRLKRKIECGAEYFISQP
VFDKERIIAISEATRGVSAPIYIGIMPLTSARNAEFLHNEVPGIRLPDDVRAKMAATSGK
EEARQMSFAICRELIDTAMAHFRGIYLITPMGHYSMSVDLVKYIKKKEREYAALENSENI
LL
>A0A1F4LP18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFCSPLOWO2_12_FULL_65_40|TrEMBL
MTAANAPSTGVPVSFEFFPPKTPEGAEKLRAVRQQLYALRPEFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREQLAQLRAMGVQRLVALRGDLPSGYGMGGEFHY
ASDLVAFIRAETGQDFHIEVAAYPEVHPQARSPEADLKAYVTKVQAGADAAITQYFYSAD
AYFRFVEDARRQGADVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDVASI
RAFGLDVVTGLCEQLLAAGVPALHFYTMNQSVATLEICRRLESSLGKRT
>A0A318L9T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rivicola pingtungensis|TrEMBL
MHSQSNPRTFSFEFFPAKTPEGMAKLRTTRQQLAQFKPEFFSVTFGAGGSTRDRTLDTVL
EIRNEGYAAAPHLSCIGSSRDNIRAILNEYRNHGIRHIVALRGDIPSGMGEFGEFRFANE
LVEFIRAEHGDHFHIEVAAYPEYHPQARSAHDDLRNFAVKVKAGANSAITQYFFNADAYF
AFVDEVNALGVDIPIVPGIMPINNFSQLARFSDACGAEIPRWLRLKLQSYADDVASIRSL
GLDVITALCDRLLAGGAPGLHFYTLNQAGAVSTICQRLGL
>F9Q5W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus pittmaniae HK 85|TrEMBL
MLWDSIHRLKTLKPKFVSVTYGANSGERDRTHSIVKAIKSETGLEAAPHLTGIDATPEEL
KQIAKDYWASGIRRIVALRGDIPAGYDKKPFYAADLVELLRSVADFDISVAAYPEVHPEA
KSAQADLINLKRKIDAGANHVITQFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQ
LQKMASFTNVKIPTWLAKAYEGLDDDQTTRNLVAASVAMDMVKVLSREGVHDFHFYTLNR
SELTYAICHTLGVRPNL
>A0A7W8GBB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema ruminis|TrEMBL
MKIVDILNSKKVSLSFEVFPPKKQEALESIKKTAVELTSLNPDFISVTFGAGGSTQGYTA
DIAQAIENQGTTALAHLTCVRSTSEALNHIISNLKEKNISNVLALRGDFPKDSVEGENVF
PSGFVHASDLVTLLKKEGFCVGGACYPEGHPESTSRETDIENLKHKVDAGVDFLTTQMFF
DNDMLYSFLYRLQSAGIHVPVLAGIMPITNANQVSRMVDLSNAYIPRKLLAICDRFKNSP
EAMKQAGIAYATDQIIDLISNGVRGIHIYTMNKPEIAKAIISNVNEIIKATNL
>A0A836RAQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MRIRDVYRTRTLAVSIEIFPPKTKQGDANLWQSLERLASYQPAFISCTYGAGGTTRERTI
ELCVQVQEKYRVTATAHLSCVGATRSELAEWVADAVAKGIRNVMALRGDPPQGERVFRPV
PGGLAHANELVALIRERHPDVGIGVAGYPETHKEAPNPETDLENLRRKVEAGADAVFTQL
FYVNERFFDFWRRYEQAGISVPLIPGIMPITEFSRIRRISDLCGAQFPEPLARRLEANQQ
DRAAQFEIGVEHAIEQCRELVEAGVPGIHFYVLNRSRACERILDALGMQPEGEGQGTASR
QQSQRATGTGREEGT
>A0A0B1T5V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oesophagostomum dentatum|TrEMBL
MKWFSPFWCVKVGHGNKYVPLHERIDRRIKDKTPFFSLEFFPPKTANGVANFFTRLDRFN
EGGPLFVDITWHLGSDPANMNKETSSSSIAAGCLDYCRVDTMLHMTCAQYSKEQTIKHLE
QSKSVGLRNILALRGDLPNIVRSLRKDTDDAPIYKYRALDMIRWIREEFGDYFTIACSGT
SLKGPLNYRDDYVVKFCAT
>A0A4Q7QRB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fictibacillus sp. BK138|TrEMBL
MSLVNDLQQNKILIGDGAMGTLLYSYGSDFCYEELNLSQPEQIYNIHQAYLNAGADIIQT
NTYAANYSKLERYGLQDQVKEINKAAVQIARRAAKNQYVLGTIGGIRGIKPNSISLDEIK
RSFREQLYCLLMENVDGIQLETYYDLQELETVLEIARKETSLPIISQVSLQEIGFLQDRT
PISEALLHLEEIGADVVGLNCRLGPYHMLKTLEEVPIPKKAFLSAFPNASLPSYSDGKFQ
YESDAEYFKECAHLFRQQGVSVLGGCCGTTPEHIRAFSTELKHLQPVKEKEVKQRKRDIV
IKSASKSKYVPLCEEVKKKQSIIVELDPPRKLDTSRFMEGAKALKEAGIDALTMADNSLA
SPRICNSALGSVVQSELNLRPLVHITCRDRNLIGLQSHLMGLHTHGIREVLAVTGDPASV
GDFPGASSVYDVTSFELIKLIKQFNQGLSLSGKELGEKTSFSVGAAFNPNIRLIDKAVER
LEKKIEFGADYFISQPVFSQEKLIETYEATKHIDKPIYIGIMPLTSSQNAEFLHHEVPGI
KLSDAVREQMGKYKENPKQASVEGLNIAKSLLDTAMDLFNGIYLITPFMRYELTVELVNY
ARTNHPSLLARRSLNA
>A0A6P0PQB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO4E2|TrEMBL
GDPVKAGDHPDAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKS
WSGLQSRFERKLEAGAQFFQSQLICDFDRLEKFMVQIAAGTNKPILAGIFLLKSAKNAKF
INKKVPGVNIPDEIIDRLAAADNQLQEGIKIAAEQVKLARQLCQGVHMMAVRREDLIPQI
LDLAGISPLQKSSPVNDLVFK
>A0A846WP79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia polyisoprenivorans|TrEMBL
MTSSPPALSVVERLAAPPANGVVHFSVEFMPPRDIEGEARLWRAVRVFERLDPAFVSLTY
GAGGSTRDRTVRIAGELATQTTLLTVAHLTAVNHSIAELRALVGSYADQGITNLLALRGD
PPGDPLGEWIRHPQGVQYARELVELISGLGDFHVGVASFPEGHHRARDLDQDTDVLVGKL
RAGAEYSVTQMFFDVEDFLRLRDRVARADPEQAAKPIIPGLMPITSLASARRMTQLSGSV
IPPAVEQRFAEAAGDGPEEDRAAVRAVGIDFATETAQRLIAEGVAGLHFCSLNFAKATCE
VLDRLGVGVPDALPTVGAR
>A0A1Q7A937|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ktedonobacter sp. 13_2_20CM_2_56_8|TrEMBL
MQHDFLEQLQQHPLLCDGAMGTLLYARGIAYERCFDELNLTRPALIQGIHSEYISAGAQI
IETNTFGANRAKLEAYNLEGRVRDINRHAVKLAREAREISGQSVFIAGAVGPSGRPLQAP
DEQRLSELRAIFREQIDALLVGGADLLILETFSSLAELRQAVLAAQDVGGLPIVAQMSFY
EDGHTLSGQSPARVAAVLNDLGIDVMGANCSVGPAATLDVLQEMIAAARLFLDNEQAIPQ
MFSAQPNAGLPTRIGNRFFYMATPDYFADYAVRFARAGVQLIGGCCGTTPHHIAAMRKAL
NDAYGAATPSIPGSSRETLQAKPVEITNGKVTIAGLIEEEVILPQQGTKTRLQEKLAARE
FVVSVELDPPKGLNPAKILEGAAMLQKVGVDFINIADSPMARVRMGCIALARLIQDHLGI
ETIIHFTTRDRNLMALQSELLGAHALGIRNILSLTGDPLHVGDYPNTTGVWDLDSVGLIQ
VLRRMNEGHDAAGSSIGAQASFHIGMALNLNMTEQETEQEIDKYRRKIEAGAHFIMTQPI
YELARLECFLARVGKPPIPMLLGCIPLHSSRHAEFLHNEVPGITIPDDVRSRMRAAGDQG
HEEGLKLAQELLTSARSMIQGVYLMPSYGRYDVVSKLTKMLQMQPTP
>A0A1R4J226|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. JB385|TrEMBL
MSKPAFSFEFFPAKTEQGHQKLLGTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALSI
RGETDIAPHMSCIGDDKAEIAELLEHYKSLGINRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFRIEVAAYPEMHPQARSFEFDVDNLVNKFQAGANAAITQFFYNADSYLYLR
DTLEKRGIDTTTQPLVAGIMPITNSSNLIRFADSCGADIPRYVRKQLFDYGDDSKAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVEALGLTG
>A0A087NAP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. ba1|TrEMBL
MMTLPSIHPNWDLPPKGMTDGYSLEITAKDIDALREAAPTMAAETPVAVTFLPGESLEAR
IAAAKLVRSLGFEPMPHFSARRLESGDDFETYLAAVVREAGVQRCFVIAGDPPEAAGPYS
DSMALIRTGAFERAGIKAIGVGGHPEGHPNMTPDQCFAVLTEKCAEIEQRGMAPLIVTQF
SFDAAPVLSWLAELRQRGIDAPVRIGIPGPAGIKTLMRFAARCGVGASASVLTKYGISIT
KLIGTAGPDKLVDALASGLGDQHGKVRLHFYPFGGLSKTVEWINDYTARH
>A0A158DE44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia hypogeia|TrEMBL
MRGRCRPSKNIMKPIELSFEFFPPKTQEGVDKLRASRAELKKLKPKFVSVTFGAGGSTQQ
GTLDTVLEMASEGFEAAPHLSCIGSSKENLRAILLNYREHGIRHIVALRGDLPSGMGEVG
ELRYASELVAFIRQEHGDWFKIEVAGYPEFHPQSKSPKADLDNFARKVKAGANSAITQYF
FNADSYFKFVEEARKLGVDVPIVPGIMPITNFSQLMRFSDMCGAEVPKWVARRLESYGDD
RESIRAFGLDVVTGLCRRLIDEGAPGLHFYTLNGAAASKTICERLGFKSA
>A0A2R8ALU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliiroseovarius pelagivivens|TrEMBL
MITPNISFEFFPPQSLDASFRLWETVRQLAPLDPNFVSVTYGAGGTTRELTHDAVGTIHK
HYGLNVAAHLTCVDASREETLAIAKSYAEVGVTEIVALRGDAPKGTDHFAPREDGFENSV
ELIEALANTSDFHIRVGAYPDPHPEASDLDADVAWLKRKVDAGAGSAITQFFFEADTFFR
FRDKCEKAGIDVPIIPGILPIENWKGVRKFAERCGATVPTWLDDAFHKAERDNRTDLLAT
AICTELCSDLIEGGVEDLHFYTLNKPGLTRDVAHALGVTPQISLANVA
>A0A507QTI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monascus purpureus|TrEMBL
MHVKDKLAQEEASGKPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAALDAAYKAGCTNILALRGDPPREKES
WEITEGGFRYAKDLVKYIREKYGDHFDIGVGGYPEGTDDNLDIDLLIDHLKEKVDAGSSF
IITQMFYDADNFISWMKKVREKGIKVPILPGIMPIQTYAAFIRRSNYTKIRIPEGWLAAL
EPVKNDDAAVRDIGKHLIADMCRKLFQAGIYHLHFYTMNLAQATRLVLEELNLIPSEETP
LPRPLPWRPSLGLKRRGEDVRPIFWRNRKTSYIARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGQPKSIQDLSELLIRFIEGKLDRLPWSDAPITAESNAIKDNLID
LNKRGFLTVNSQPAVNGAKSSHPVYGWGPNNGFVYQKAYLELLVPPNLIDELISRIEKNP
DFTYHSVNKSGQLKTNTRDSPNALTWGIFPGREIIQPTIVDTVSFLAWKDEAYRLGEDWA
KCHDANSPSRKLIQNVMDEWYLVNIVHNDFHWTLDIFDLFKDLTVKDLQAEVPATANGVP
EANGALAAAAASTSN
>A0A3D8UFM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium breve|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQAVGEFNHASDLV
SYIRSVKPDLKVFGACYPEGHYQADTIDQDIENLKIKVDAGATHLISQLFYDNEDFYRFL
DKARVAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A1E7JD31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium S5133MH4|TrEMBL
MNFKQALESGKFLVTAEIGPGKGTEISRLLEDASAIKKRVDAINVTDQQSSVMRLGSLAC
CHLLTDLGIDPILQLTCRDRNRLALQSDLLSAWVLGVRNVLALTGDHPVMGDHPEAKGVF
DLDSVSLLKVITELNNGSDMAGNKLTGCPDFSAGAVVNPGADTGAALDLQIIKLEKKIAA
GAKYIQTQAIYDLDLFEKFIKRVKGFDVPILGGIILLKSAGMARFMNKNVAGVSVPDNMI
KEMLDTEDKVKTSVEIAARLIKGLKDLCQGVHIMAIGWEKKIPAVLDEAGI
>A0A3C1BCZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp|TrEMBL
MKITEHIKNANGKTLFSFELIPPLKGRSIQGLYDAIDPLMEFKPPFIDVTSLREDYIYKQ
HESGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLVDLQFLGIEN
VLVLRGDARSADASFVPAPNGHCYATDLLQQVVNMNNGIYLHENSSDNLKTDFCIGVAGY
PEKHFEAPNLKSDFKFLKQKVDMGAGFIVTQMFFDNQKYFDFVNSCRANGINVPIIPGLK
PVTTSKQLVNLSKTFHIDMPEDLCDSINSCKSEKDVKDAGIEWTINQCRELIKFGVPVLH
FYTMSNAGPTKKIAEAIF
>A0A2E7EPL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MALSEFFGRDRFGLSFELFPPKTDAGLKTLYRHVEVLLDFSPDFFTCTYGAGGSTQEKTL
EIVAAVKERFGVHVASHLTCVGSTVEELKRYLRTASERGVDSIVALRGDPPQGEEQFTAV
DGGLQYANELVSLIQAEFGQFGIAVAGYPETHQEAPNADVDLENLKRKVDCGADLVVTQL
FYNNEDFFRFQDRCTAAGITVPVIPGLLPVTNLHQIQRITSLCGASLPASFVNRLSEHED
DADWQFKVGVEFAIEQVRQLIEHGVPGIHFYVLNKSQATSQVLRSLDLPHRDVVAR
>A0A0F0FWJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium 16|TrEMBL
MQDRYFSFEFFPPKTAEGAEKLRNTRAQLAPLHPKFISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRDILKTYRDGGIRHIVALRGDMPSGMGEIGEFRFANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRAMGVEVPIVPGIMPITNSSQLMRFSEMCGAEVPRWVAKRLEGFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNTASATKAIWQRLKL
>A0A2E8FMQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MSSLAEIYAGHSVAVPPVISIEVFPPKTADGDQVLLDTLDQLAIYRPRFISCTYGAGGTT
RDRTIQLCQQIQSRYACTATAHLTCVGSTCEELLEWIDRARRAGIVNIMALRGDPPQGQG
GFTTVPGGLAHADELVALIRGKSDELGVGVAAYPEVHPEAADAASDLANLKRKVDAGADA
AFTQLFFRNASFLDFRDEFDRVGVGVPLVPGIMPITEFSRIRRIAALCGAIIPEGLAAEL
EAVRDDRDAQFEVGVAHAVAQCAELISEGVPGIHFYALNRSRACAEILEALGWGLDDGVV
R
>A0A0F3L161|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter yeojuensis|TrEMBL
MPAISFEFFPPKTDEQRDQLDKAVERLKGHAPDYVSVTFGAGGSTLSYTGETVKHLRSEH
GLSVAPHLSCMGGSKAEIRALLDEYKERGCRRIVALRGDLPSGMATPGDFRFAAELVAFI
REHSGDHFHIEVAAYPETHPQAENALADLRHFKAKCDAGANGAITQYFFNPDAYFRFVDD
VGRLGVTVPIVPGIMPIANFSQLRRFSEQCGAEIPRWIVKRMQAHGDDAAAVRELGADVV
AELCRRLLDAGAPGLHFYTINRARATTAVLERLA
>A0A546XM66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium rhizogenes|TrEMBL
MRSETARRDGDIRLSFEFFPPKNAEMETHLWETVAELKKWNPDFVSVTYGAGGSTKAPTL
DAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIGTAYKP
HPEGYENAAALVKGLREIGDFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQF
FFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFEGYDE
DLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVEAVLENLGLERLRRSAA
>A0A7Y2VNZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eudoraea sp|TrEMBL
MKVTEHIERAKGETLFSFEIIPPVKGRSIKELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYDVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNI
MALRGDAMKGEQYFEPTKGGHKYASELVSQIRNLNSGQYLHEVIETDNCSDFCIGVAGYP
EKHMEAPSMKTDLKWLKKKVDLGAQYIVTQMFFDNQKYFDFVTAAREAGI
>A0A2V7AH25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFSRRLDAGPLLCDGAMGTMLYARGVSLDACFDVLNLHQPKVVQAIHADYIAAGADC
IETNTFGANRFKLAVHGLADRVREINTRGVRLARDVRESAGRDVFVLGSIGPLGKYLAPL
GTVTAEEARVAFREQAEALLEGGVDAFVVETFSDFAEIALALEAVRSITDLPIVAEMAFT
NEGVTFTGRSAVDVARSLAGRGVQALGANCSVGSSTLHEVLEQMLPAAGGIPLAVQPNAG
LPSRIDERLIYLSSPAYMAEYAGRMVDAGARLVGGCCGTTPQHIAAMREVLDRKTSVRRE
TRRPVVSVSTPAVREATGLRTLRAPTTLERRLRDREFVVTVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLATALLVREATGLDVNMHFTCRDRNLMGIQADLLGAY
ALDVRNILAMTGDPPRAGDYADATAVFDVDGIGLIEIIRRMNEGLDATGASIGEPTSFFV
GAALNPAAAEVGREVERFHRKLEAGARWVQTQPVYDLAALDSFLERAGGSPQPVLVGVLP
LHSFRHAEFLHNEVPGISIPEPVRRRLKDAGDGALRVGIEMAQELVREVRGRYAGAYLMP
SFGRFEVVAEVLDAMH
>A0A846RPI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium marinum|TrEMBL
MAKLIAKTPQEKRALAGLLDNIGYEVMPFKSAVSKVISDVPTEVPLTITATGGKGLEPTL
NATIELTEKGYTVAPHIPARLVAGPEELDQIATRLETAGVNRIFIVAGDAEQPAGLFNDA
LDLLKALKVRGHSFSNIGIGGYPEGHALLPDEKVNRAVHDKAPFADRILTQICFSSDTLL
AWGARLKAEGIGLPTFVGMPGPVRRQKLMRISAGLGLGQSANFLKKQQNMFWRFFSPSGY
TPTKLIRGLVQDLSKSDTMITGLHIFTFNDLARTEAWRRDLIEQTQ
>A0A182QTL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles farauti|TrEMBL
MAAVDDDDVLRTKLDRIFDTRPSADTSAKPTVSYSIEIAAKDDFDIARLQNLTPQPIFCS
LPWISDDNLRYADDFPRSPTLQLAGRLREAQYTVVTHVSCYNITEQQVDRLFDSTDIRNA
FVIRGDTVNPAQRFQNSADLVEYLRKREHPHRLTLGVGGYPYGHHQSPSVADELRYLRAK
IDRGVDYLLTQTLYDAGSYFRYRDRCRRAGISVPIVPGIYVPHSYRHLQAMLALTRIQLP
PTVRDAFEAHANDAPEQFEAFAIEYFVGVVRELLEPNDAAGLNEPPVRLVHFFTFNKLGV
LEKVLQQLGEFFQ
>A0A8A3PF74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monilinia vaccinii-corymbosi|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRAVDEENGDTPGMDWEFEWAIDLVRYIRKKYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLSYLVEKVQAGADFIMTQLFFDVDAYDKFEQILRGHPSEAFKTLPIIPGMMPIQSYQMI
KRTTKLSHAKLPTNIIKRLDQVRGDDEMVKKVGVDILSEMVEHLKDTKSRYPGPRGFHFY
TLNLEKAVSFILERTNLIPDADTAAALEPELVPTIPDIADLLSVHTHSHKRSSRRRSSVG
SDPYNRVIITAPQTSNPSFEATAQEAGVPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGVKSTDPIFGWGPKNGFVFQKAFVELFL
PTSMWETLRAKLTSPALRDTVSFYASNSKGDFSCSDKSVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSATRKVIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLQ
>A0A8J3A5J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquisalinus luteolus|TrEMBL
MSDKLKISFEFFPPKTEKMSEQLWSAIEQLVPLGPDFVSVTYGAGGSTRDRTHQTVSRII
EETHVPVAAHLTTVNATKDEINQVLDDYWNAGVRHIVALRGDPPGGVGEKFEATEGGYYN
AAELAKAATDRHGFEVSVGCYPEKHPESPDFALDIELLKQKVDAGATRAITQFFFDNDCY
FRYVDMVRKAGITIPIVPGIMPVNNFGALTRMAGLCGATIPGRIGRMFENLDDDPETREL
VAATLAAEQCLDLAEHGIEHFHFYTLNRAKMAYALSHMLGVRPNSGNSQD
>A0A2V6RLR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPSAFSQRLDAGPLLCDGAMGTMLYARGVSLDACFDVLNLNNPRLVQAIHAEYVAAGADL
IETNTFGANRFKLAAHGLESQVREVNRRGVRLARDVRESTGRDVLILGSVGPLGKYLAPL
GSVTAEDARAAFREQAEGLLEGGVDACIVETFSDLAEIALAIEAIRSVTDLPIVAQMAFT
DEGVTFTGRSPAEVGRTLRALGVQALGANCSVGSSTLYGVLEQMVPAAGSLPLAIQPNAG
LPSRVGERLIYLSSPAYMAEYAARMVEAGARIVGGCCGTTPQHIAAMREALDRQRPPRRD
AVRPTITVTAPVLRESAGLLTRRPATTLQRKLEAREFVVTVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLPTALLVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALDVRNILALKGDPPRAGDYVSTTAVFDVNATGLIEVLKRMNQGLDATGNSIGLPTSFCV
GAALNPGAENIKAEISRFHRKVHAGAQWLQTQPVYDLAELDRFLEQAGGPPVPVIVGVLP
LHSYRHAEFLHNEVPGITVPEQIRARLRDAGDGALRVGIEMAQRLVREIRSRYAGVYLMP
SFGRFEVVAEVLDALH
>A0A1Q9SAN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria sp. CNJ-770|TrEMBL
MRRPPDRTAPPPSLSYELYPPRCAASAETLLRTIEELEPTRPDHVAVTYSGDAPRRAGSL
ALLDHLLARTGLRPVAHLTCVGSTRAELEETVASLLHRGVRGVLALRGDLEPGAEPGELA
HAGDLVELVREVEQRRTASLAGGRLAVGVAAYPTRHPESPSFRHDIEVLLAKQRAGADFA
ITQVYFRPQRYERLVASARAAGVTIPIVPGIMPVTEPRRLATLCRLAGLRPHPGLAAALE
GAAGPAERHRAGVAFATRLARAALDAGAPGLHLYTFNGHRAALDLLERVDLPRVPHQPAA
LPDLLPA
>F7YES3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium opportunistum (strain LMG 24607 / HAMBI 3007 / WSM2075)|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKSDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILQETSLTPAAHMTCVDAARHEVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHADGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A346R4F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Breoghania sp. L-A4|TrEMBL
MSPSAKHAPSARDAAIEVSFEFFPPKSEAMEKTLWRSIERLAPVAPSFVSVTYGAGGSTR
ERTHNTVARILRETELKPAAHLTCVAASRAEVDAVIQDYWDIGVRHIVALRGDPVDGLGA
AYKPHPEGYVNAAGLVSGIRAIGDFDISVAAYPERHPESADWGVELDNLKRKVDAGASRA
ITQFFFDNDLFERFLERVRAAGITIPIVPGITPIHNFTQVASFSKKCGTSIPAKLAENFQ
GLDDDEETRKLVAAAVAAEQVMDLVGRGISDFHFYTMNKADLVFAICHLLGLRPRNGEQR
AA
>A0A524KXS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium|TrEMBL
MRIAERLNSGKQFLSLEFFPPKNSSDWPAFFNVVDSLKILQPLFVSVTYGAGGSTSDNTL
AIVTRLKQEFSLEPMAHLTCVGATEKSILSFLEDLKAVGVDNVLALRGDPPQDPGFVLPE
SKDFVFASDLVTFIRKHYPSMGIGVAGYPEGHPEAASLEKDLQFLKHKVDQGGDFVVSQL
FFDNDYYWDFVQRARDLGIEKPIVPGVMPIFSLKVIKKVVSLCGATVPAQLLRELEAADA
QGGADAVQALGIRHARSQILGLLKGGAPGVHLYTLNRDDACLELLEGIF
>A0A3P1W591|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium OH3737_COT-264|TrEMBL
MPAPTPALPLSLEFFPPKTEAGALKLRQARQQLYALAPQFCSVTYGAGGSTQAGTFATVG
EILAEGQDAASHFSCIGAHAAKLRAELQELRDMGVKRLVALRGDLPSGYGISSGQAEQRF
QYASDLVAFVREETGAHFHIEVAAYPEMHPQAASPQKDLQAFAAKVRAGADSAITQYFFN
ADAYFRFVDEARALGVDVPIVPGIMPIMGASQLLRFSDACGAEVPRWIRTRLQALGDDVD
GIRAFGLDAVTALCERLIAGGAPGLHFYTMNQSPLVLEIAQRLGLHPSTPAAPTMPAA
>A0A258X2H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacterales bacterium 16-40-21|TrEMBL
MFESFIQKLRHGTFITLETTPSRSAQFAPTIEKIAALGLDSLVDGFSTTDNPLAKLKYNA
LFAAMKLQDRFGKPTLATMSMRDRNRIGLQSDLLGSNESGVRAILALTGDSAHYSDQPHS
KGVFEGNSNLLLDIITTLNSGTDMAEQKLIAPVQEIYPFAVIDSYSKNTNALQKKMVKKV
SHGAIALVTQPVYDTAIAQQLLTMMEEANALNPEREKCILVLGYFPITKLRTAKFLDENV
PGIHVPSSWVEALEKASLVSVEEEYKVGFELSKKLFEDLKALHPKIHIMTANQFELAKAI
LS
>M6D6C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira sp. B5-022|TrEMBL
MKKILEIYKTAKAPVYSFEFFPPKTPEGETKLFEAVEELSKVDPGYITVTYGAGGSTRDK
TIRITSELAKKFSLPAAAHFTCVGGNKDEIRVILKQIRESGIENLMALRGDPPKGEGTFK
KVEGGFGYASELISFIKQEGFDFCMGAACYPEKHPEAPSLESDVDNLKRKVDSGASYLVS
QLFFKNSNFESFLDLIRKKGINVPVIPGIMPITSFAQIERFRSMAACEFPEKLVSDLEEV
KDIPEEFYKRSIQFSVGQCRELVKLGAPGIHLYTLNQSPASLDIVRELKN
>M3A5Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum caucaseum|TrEMBL
MSLPRSELPIAAASRQPVSVSFEFFPPKTDKMQQSLWECIERLAPLAPQFVSVTYGAGGT
TRERTHETVVRIARETRLKPAAHLTCVGHAKGEVDDIARRYWDEGIRHIVALRGDMPEGG
AYVAHPEGYAYAADLVAGLKRIADFEISVAAYPETHPDAPSAGFDLDNLKRKIDAGASRA
ISQYFFDPAVFLAFRERTARAGITVPILPGILPVTNFAQVQKFSAACGASIPGWMADLFQ
GLDDDPETRRLVAATMAAEQCRILAAEGVEQFHFYTLNRADLAYAISHILGVRPKG
>F7Y296|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium opportunistum (strain LMG 24607 / HAMBI 3007 / WSM2075)|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A8H5LY52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetrapyrgos nigripes|TrEMBL
MVLLASLKPLATSVTWGAGGSTKERSLDLAGLTQSNFGTDVILHLTCTNMVQGMVDDALQ
TNPSPPRNVEFRIFWLFEEVSIASDTAKDSVSEHPPRGKEEWIPIDPNFQHGVDLVSYIR
SKPEFATHFCVGVAAYPEGHPDKLTDEETELEHLRQKIDAGADFIITQVFYDVDRFLIWI
KKVREKGINVPIIPGVMPIQTYSSFIRLVKLCGINVPQSLLAALDEINHDDQLIKNYGVE
LAVNMVRRITTEGDVPGVHFCTLNLEKSVQRVLEQLQWTGISHPFQNKLISDDLTPKSEH
NADERMVSPSAAANAATVNFANIPSTETEAGSGELNKADSWDDFPNGRFGDFKSPAYGDQ
GPWGNSGVIRPQTLSEWGNPQALNDLTTLFLNHLHSKISTTPFSPGPLSAESLRILPHLE
KLTKRGWWTVGSQPAVDAVNSADEVVGWGPKTGYVFQKGFVEFFCTEDDLKVIEEKVKQK
GIGLVHYFAANSDGECVGNVPQDARNAVTWGVFAGQEVIQTTIIEQENFLAWAEEAFSIW
KHWASFYRPGSPERILLASVHNDHWLVSVVHHDYKDSEALWTFLPSQKPYKDLSKKSSAE
HTHSKPPQNGFPIPPENLTHITAYLDPSSLFTLSCVNQSFYDHVKDDHTWHRAFLLNFLG
ISPEGDLDDEKMLLLRRSEPTWRREYVFRYNLLRRWAKSTNTTIAHAPVHSPISDMRLMP
GNSLLCSSVQYGIVSRSIVFTGRIIRGFLSPSPSGTGLGIGNPNTEFAPNVSVCALGSEG
GTAKIAWGFRNGDVAIMTAARTMETSSRSAAKLVRCSIADKHDGEVVHIAWDESGSHVIT
VAKDGRVKVWEAKKVQCIWSSEYLVPDVCTRVEFSIRSGCVVAALRSGDIVLWTGLDFTS
PLNLESLGTRIPCPDDARTKNEDHILPVVTSVHLDPAGSVLISYQSVSRFYRVFITDPKE
IIVTRLYDPTFVGAGSITRLLPCYPTSKLGERGFVLAGDKTGCISVYPYSSDPVDVVSPI
RRFEAHEDGAAVTALSWDGLTLVSGSANGSTAVFDAVTLKKLRVFDTPVPRSRGIVPTVG
VLTEDTPEGVKQIILGPEKDVLVVSVGSRVMGFKADPVSKNRKPKTLANGKKKARGTAMS
KGYDQHVLKKLVSESITELEQDTDRRRRVYGRQREQMLNLEELGLDEVEAVEYVLMLSRD
EAQQRERERLQSLPIEEGVFEGDFDDIGSTSQDLEDDSGFTTSSGSSNAPDTDSIPSTSP
SISRSPSTAPSLSSSPQPNRSSSSMSISMTMFSAGTPKSPGRGISISRQSPRGSPSSSIQ
KIQISSRSPRIEPMEAGFGDDDFQLGQTRSSYVSSSLSSSFGELRVNQPNDIDNDAAIAA
VLAQGDGATEHFPAIDGKVDDRTTRGKGKAPSKSAWSRPLANVHKSAPNHDAQSPPAKKA
WSTGSTSAIVSSSTATVSSSKHSRSGRPGAVQHEDQEDEDLKLAIMLSLEDARKRGQIPS
SKDMSYRGDRGRGSDRGRGSDRGRGFDRGRGRGGGDFRGGGRGGGRGGAPPSWYTSVFVP
TGAAQAVVDQRLTDGTQDALVASFGALSLRSSDLPLRPGFGIEGRPIKLRANFFPVKVPK
GPLFEYDVQISPAAGTANRRVKRRIFQLAEQTREWASQGLRGMVAHDHSSKLIAAKKLPD
PLSIHVPFYDEEEQGPRQDGKQYTLKFNFVQPIDTSALSEYLKANAQYKDYDILPIISAL
NIILAAHPSRTAPGGGVLVGRNRFFFPSQDQPVPLGGGLEAFRGFYSSVRPSYKQLMVNV
NACTTAFYSPGNLADALQEFMNASFGARPNAFVKGVRIRTVHLGYRKTVKGIANVTAKQH
QFDCADLGGRVTVEVYFKRKHNVTLRYPNMPLVDVGGQKSNLLPPEMCEILPNQPFKGKL
LDTQTEQMIRVAARPPNVNAQSIVGPGIERLGFKTGADPLRAFGISIGSDMTIVPGRILP
PPGIRYSRNAPVVDDRASWNLKGVKFAQGARLSKWAVLVIRDGNSRDEFNARDDPELLGI
LRGFSQMCAASGMTVDPGQPLINAVQLPRKDNSDPIRAKAIDAIKTTITSFPGKPNLILV
ILSNGDKHVYSGIKHLCDAYLDIPTVCVHSSKIRKEKGQLQYFANVALKVNMKLGGVNHK
LDEQTMGWFSKQPTMLVGIDVTHPGPGSVKGTPSIAAVVASVDSDFGQFPASMELQESKK
EASLKHSSKMVTNLKVMMVERLKLFQARNGGKLPARVLVYRDGVSEGQFNQVVDQEMPEM
LAAFKKFDTPQKRYTPKLTIVICGKRHHTRFYPTDPQNADQNGNPKAGTIVDRGVTAVYN
FDFFLQAHGGLQGTTKPTHYYVVHDDIGFGADELQKLTNSVSYLFARATKAVSLASPAYY
ADLACERGRCYLHKLLHGITSVNTNLSNVDDLVMREALQSWNNGVSGATLKDTMYYLLRL
ESILNWAQGQLQPMPNSGNNSRPMSGSRSFQASHSLYASASSSRPFLNMLNPMSRQYQGY
TQANQSPLEEEEDDKNSADSDEDEDLETGHSRSTIFRRDADTPLRSLSKSQSKRRVSWDA
EGSKVAHPNIKQEDAVEESESDGEVPQSFMIEATSRKPTKITFKDKGKEPSAGRRQPLYS
VSGRSVPPILPTHTPTPTPVSIPPRPSEVDGEHTPRAETFSEASERERPRRSSGLDAHER
ALWNWVNVYNLDAFLQEVYYYYEGKGIYSIALSRGLNLLTVGFVIGFSTFLLGCIDYSRI
RHDEYTRLSEVIVGRCVSRFSGFTLLFFLPFTAFYIWQIVTFVLGIRRLIDMYNFYTHLL
KIPDTISWPEVVRRIGMIRQDNPLTAISSKSSGNIDDTTTAKLDAHDIANRILRQENYLI
ALFNKDVLDLRVPLPRLLKRFVPEEKGKGKMLTRALEWNLRFCLMEYLFDTHGREYHKDP
STIGGRRYTSFAQWKFREFNELPHLFVRRLDESYPIANIYIGQFPNEKMTLIMRFVAFVS
GSFVAVLFLATVWDPDVVVHFEITPHRTVLFYLTLFGSVLAVARGMIPDENRVFDPEMLM
TELITYTHYMPDSWKDQLHSKKVHQEFGELFAMKILIFIQELLSVVLTPFVLWFSLPACA
PAIIDFFREFTVHVDGRGYVCSFAEFNFERHGNVKFGAPAQVDKRMVSNEGKMEKSFLNF
KAANPEWTPDPSGSLYLSRMHDFTAAHPTSFIRRRHGVEASGALSPTSKPTTESSLADRA
QEYERALKQSQYAARKRVPGGSILGMSTLAPGSQSQGPSASSIFGAMAGAQTAVLGDSQG
SIAVAHASKPEALDEPESSRIAAMSNEEIGPDGEVGGSLGGSYVDGGRRPRPAQEEEEED
GLEDGGVLGLLAQIYGKRDGPQVM
>A0A6P1DSH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gelidibacter sp|TrEMBL
MKVTDHIKQAKGKTLFSFEIVPPQKGQNIQELYDNINPLMEFKPPFIDVTTSREEHLYIS
KGEGLLEQKITRMRPGTVGICASLKYKYNVDAIPHVLCGGFTKEETEYLLVDCHYLGLDN
VMALRGDAMKHEKYFAQTKGGHQYATELVTQISDLNKGKYLHEIEETLYKPDFCIGVAGY
PEKHMESPSLDADLRRLKEKIKAGADYVVTQMFFDNQKFFDFVEKARAIGITVPIIPGIK
PIAIKRHLQVLPQVFKLDLPEALIAEIEKCSNNEQVREVGVEWAIAQSKELVAKGVRVVH
FYSMGKSDNIKAIAKEVF
>A0A2R6F007|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QH_8_67_36|TrEMBL
MALKSPVSGDQEGVETLLRNARFELMPFDSFDEEIEHLPAGATIAITTSPQLGIDRTVEK
TEMAMQEGFEVIPHVAARYVEDREHLEDVARRLTEAGVTDVFVPGGDREEPAGEFESAYD
LLTVLDGMDYEFEDIGITGYPEGHDFLDNETLAESMQRKEPYATYIVTQLCYDPETVLEW
IDDIRARGVDLPVEIGIPGVMKYQRLMQISRKVGVGDSVKFLKKTTGILGFVKQLIGSRG
TYEPDDLVDGFGPHMDDEAYGIRGIHIYTFNQTPDTENWRRSRLSS
>A0A8B9TAL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anas platyrhynchos|TrEMBL
ALYTPCSLCSPPPESSPCSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDRWFS
LEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCG
LETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVKH
IRNEFDDYFDICVAGYPKGHPEAESYESDLKHLKEKVLAGFMKDCQAIGITCPIIPGIFP
IQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGL
HFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRT
QEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTCEESVFEVFTCY
ISGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNINGKPSTDPIV
GWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYESRVNYHIVNVKGQNITNAPDLQPNA
VTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYL
VNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A1G0RCS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium GWF2_33_9|TrEMBL
MKEKFLDKLSKQIILFDGGMGTELYNKGIFINKCFDELNLTNPELIRDVHQDYKNAGADV
LETNSFGANHFKLKQFQLDDKIYEINYKAAQIAREVAGDDIFVAGAVGPLGVQMEPLGPL
SRDEVRDYYKEQLKGLLDGGVDLFIFETFIYPDELQQAILAARQLCDLPIIAQMTIDEDA
SSLTGTGAEIMIQELEQFGADVVGVNCTVGPQIMLNWLEKVREHTNLPISVMPNAGKPKN
IDGRNIYLTSPEYLGEYAKHFIQNGANVIGGCCGTTPAHIRRMKAAINAQSPNLSRQKYE
IKQIPHELKSKPIPIENKSRLARHISEGKFVKFVELLAPRGVSAAKEIEKARELFYAGID
VINIPDGPRASARMSAISLAVQLQREVGIETVLHYVCRDLNVIGIQSGLLGAYALGVKNV
LAITGDPPKLGNYPDATGVFDVDAIGLINIINRLNNGLDISGAPIGEPSGFFIGCGVNPG
AINLDEELRRLDWKIDAGAEYMITQPVFDIKVFEYFLNKIQHIKVPIIAGLWPLTSLRNA
EFMNNEVPGCIVPEEIMDRLRKVEDSKDDSRKVGVEIAYETLNMIKPMIRGVQISAPFGN
VKSVLDVLS
>A0A520G2Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp|TrEMBL
MGLPLSFEFFPTKTPEGAVKLRAVREQLYAHKPEFCSVTYGAGGSTHDGTFGAVREILQE
GCEAASHYSCIGATRATVRAQLAELKAMGVKRLVALRGDLPSGYGIGGEFHHASDLVAFI
RAETGRDFHIEVACYPEVHPQARSPQADLQAYAAKVRAGADSAITQYFYSAEAYFRFVDE
SRRLGLDIPVVPGVMPIISSTQLMRFSDACGAEIPRWIRLRLQAYGDDIASIKAFGLDVV
TDLCERLRQGGAPALHFYTMNQSQATLGVLERLG
>A0A174VBN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides thetaiotaomicron|TrEMBL
MRVIDLIHNSEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLFWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEALKCKNDKEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A318SGH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylophilus ampelinus|TrEMBL
MTASPESTSSVPAGPAALPVSFEFFPTKTPEGAVKLRAVRQALYARGPEFCSVTYGAGGS
TQEGTFATVREILAEGVDAASHFSCVGATRASVRAELAALAAMGVKRIVALRGDLPSGYG
AGGEFSYASDLVAFIRAETGSAFHIEVAAYPEVHPQARSPQADLQAYAAKVRAGADAAIT
QYFYSADAYFRFLDDSRALGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQAF
GDDTASIRAFGLDVVTGLCERLRAGGAPALHFYTMNQSAATLALLDRLLPAA
>A0A260IEQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 05-2256-B3|TrEMBL
MSEDSVRGRSSRGFVTRTPSIVDRLRTEPEARIPFSVEFSPPRDEAAEARLWRAVREFEQ
LQPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSVAELRSMVGSYADRG
ITNILVLRGDPPGDPLGEWEKHPEGVEYAEELVRMVRELGDFHVGVASFPEGHHRADDLE
QDTRCLVGKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSV
RRMLELSGTTLPSHLDEKFTRAAGSGAEEDKAAVREVGIELATNIGERLIAEGAPGLHFI
TLNFARATREVLSNLGLAAARV
>A0A370QMJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinirhabdus gelatinilytica|TrEMBL
MKVTEHIEKANGKTMFSFEILPPLKGQNINSIFENIDPLMEFNPPFIDVTYHREEYVYKE
LGNGLLEKKVVRKRPGTVGICAAIQNRYNVDAIPHILCGGFSKEDTENFLIDLGFLGIDN
VMALRGDAVKSETYFTPEKEGHAYASKLVEQISALNKGIYLDEELQNKTPTDFCIGVAGY
PEKHMEAPSLDSDIHFVKKKIEKGASYIVTQMFFDNSKYFKFVDKCRTAGINVPIIPGLK
PIATKKQLNLIPHRFSLELPDALIMEIVRCKDNKQVRQVGVDWCVAQSKELIAAGVPFVH
YYSMGKSDNIRAIASQIF
>A0A328W2G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MDMC224|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRVFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLPR
>A0A2H2ZIB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma parareesei|TrEMBL
MDRITDKIAALPAGAEYFSLEFFPPKTQMGFSNLRVRLQRMERALRPLFVNVTWGAGGST
AQKSLELAELCQRELGLTTCLHLTCTNMSQALIDQALDDARALGIRNILALRGDPPRAEY
RDADEPTEASEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLSYL
VDKVQAGADFIMTQLFFDIEAYEKFETTLRNHPSGAFKTIPILPGLMPIQSYAMIKRTTK
LSHAKMPDAIMDRLNAVKGDDEKVKMVGVDILSELVEQIREIKSRTPGPKGFHFYTLNLE
KSVSFILERTKLIPDIPEEEEAIADESPAVAAVQRMIPKISVNGNVPPRAPSHTRTARRQ
SSVGSDPHNRVIVGRAATHPEWEASSTEAGIPAGSVNTRANTLAISEGEGALGREATWDD
FPNGRFGDARSPAYGEIDGYGVSLHMSVTQAVRLWGYPKVASDINDIFVRHIRGEVSAIP
WSEEDLLPESSIIKDKLEALNRKGWWTVASQPAVNGLPSSDPTFGWGPASGFVFQKSFVE
FFLPSADWKILYDKLTSAEVEEVVCFYATNAKGDFVSSDYTGGSARAGGSESTNAVTWGV
FPGKEIVTPTIIEEVSFRAWSEEAFGIWAEWAKVYGRGSDSQKLLDGIREDYWLVNIIHH
DYVDTDALWRLLIE
>A0A1B1I2L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp. oral taxon 126|TrEMBL
MDIREHIRKEPLVFDGGMGTYYTQKTHTRGKGVELANIETPLVIEEIHAEYLRAGAQAIK
TNTFAANRIVYRGEEELVERIIRAGWKLAARAAEPFGAYVFADIGPVTGLPPADILEEYR
FLANTFLAAGARHFLFETNSSAEGLVETAAHIKQVAPDAFILTSFSAFSGGYTRDGFFVE
ELIRTVAESGYIDAVGFNCVSGVQSMKELVQLLGKCPLPLSLMPNAGHPIVIDGRTFYGN
APDYFGEGLAAIVRDGVSIVGGCCGTTPAHIRALCTALADSGSVSEEVGAQAERSTLAPS
RSPFFEALQSGEIPIAVEPDPPETGNADKFMAGARELQEAGVTVITIADNPIARARMDAA
MLAGRVQRSLGLEPIPHMTCRDRNLNAIKSILLGLSAEGVHNIIAITGDPIPTAERDEVK
SVYQFNSRKLSAFITSLGERGDVVPFHVFGALNVNSLHFPSQLGLAKKKMEAGMTGFFTQ
PVLSTRAKENLRTARDTLPGALILGGIMPVVSERNARFMESEISGIHVEERIINAYHGLD
REAAEALAVKLSLEIAKDIEPYIDGYYIITPFARTALVARIVKGLKGTI
>A0A1Y4J968|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. An192|TrEMBL
MKNARDILRDRVLVFDGGMGTYYKGRPGMECEQANLADPEGILAVHREYLDAGAEAIKTN
TFGLPRMAAAGLDNWQELAAAGWRLACRAAEGTGAAVFADLGPAPATDAAPAAQTYRAAA
QVFLDLGAENFLFETLSTDEGVAEAAAFIKERRPEAFILVSFAALPDGYTREGRSCRELA
AHMARCGHVDAVGLNCLLAPSAMASVLPAVTGCGLPVSAMPNGGYPLVTRSRVVYQGRPD
YFARELCRIRQRGGVILGGCCGTTPAHIAALRQALESTPMPIAASAPAADVPADTPLLTP
ADPFLQKLARGEKVIAVELDSPKDADLSGYVEGARRLQAAGADAVTVADCPIARARVDSS
LTACKLRRELGMVALPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLARYIHSLAGPGEALPGMTVFGALNLNARNFDVELRRAQEKQASGMAGFLT
QPVLSEAAVDNLKAARAALPDAKILAGILPVVSQRNALYMENEINGIHVDEAIIRRYEGA
DRAQGEALGLEISLEMARAAAPYADGFYLMTPFNRVALMERLIAALKQEAL
>A0A7X1ZG93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseospira navarrensis|TrEMBL
MCSRLPDHVKVSFEFFPPKTDKMADSLWTAVKRLESLSPAFVSVTYGAGGSTRERTHETV
TRIARETNLKAAAHLTCVDATRDEVDEVARRYWDAGIRHIVALRGDSPESDGVYRPTPGG
YAFAADLVEGLKKIADFEISVAAYPEIHPEAASPQADIDNLKRKIDAGATRAITQFFFDV
DCFDRFRDRAAAAGITVPIVPGILPIANFNTAVRFAGMCGAIIPPWMHELFEGLDDDAET
RKLVAAMVAAEQARALAARGAEDFHFYTLNRADLTFAICHALGVRPKTPAPQADATA
>A0A2N2PQY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-1|TrEMBL
MTQISTNGYEVGSNLERVIRSGQFVVTGELGPPQGWEREAVERKAHLLKGVVDGVNLTDN
QTAIVRMSSIAAGRILVEEGLEPIIQMTCRDRNRLSMQADLLGAYALGIRNILALSGDHQ
VFGNHPTAKNVHDIDSMQLIQMIRGLGKGVFQNGDKVVGGAMPMLIGAAANPFGDPFDFR
PYRLAKKVAAGAQFIQTQLIYDMERFREYMKRVVDMGLHEKVAILAGVGPLKSSGAAKYM
RDKVPGMIVGEYYVTEMENAIKGIPKEEKAARKEAWQRQGIELCIEQIQQLKETPGVAGV
HIMAIEWEAAVKPIVAGAGLLPRPTFN
>F7XYD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tremblaya princeps (strain PCIT)|TrEMBL
MPGLSFEFFAPRSHAGSIRLICTQQVLSRFVPRFVSVTRSATIGQQAHIDTIASTLSVFP
RTAPHVLFCQCPRALARELRAYKLLGIRHLVLLKGDNGIAPSSLGAAELVSLVRRSYGEA
FYIDVAAYPDGHPMASTIFDDVRALARKVRCGANSAITQCFFNPDAYYRLQDELQRLGVR
LPVTPGIMPVLSHDYMSRFILQSGVDVPAWILKRLEALRYCSASVLEFGTDVALSLCESL
AARGASDFHLYTMNDHRAVWRVCSHVLGSADACHRRCA
>A0A434UPV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.008.03.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A3S0V6W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio penaeicida|TrEMBL
MSYTHASHIDALNQNVAELSDDINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASRDELVNIANDYWSNGIESIVALRGD
IPPGGGVPDMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFADINNVKVPGWMAKQFE
GLDDDPMTRQLVGASQAIDMVRILSREGVKDFHFFTLNRAEMTYALCHTLGVRPQA
>A0A1W9WMY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_87|TrEMBL
MMERPARTFRKDISDPESFVITLELVPGEQSRGRSVDTVMAIAESALTDGRVSAVSITDN
PGGHPSLSPDVLGRDIIRKGMDVIVHFTCRDQNRVGLESRALQLGHMGIRNILALTGDFS
GEGFAGKGAPVFDLDSVSLLVMLKMMGEGTLALDDRENFFVGCAVSPFKQTEEEEKKGIG
RRLSVRRDWRLSSKAWDTKEPISGVSTINSTPWR
>A0A0P7Z1P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyrobacter sp. HL-46|TrEMBL
MTPTLDQLHEYRTATDTPLFSGLPGDVAVSFEFFPPKSEKMEAQLWDAVTQLQPLGPSFV
SVTYGAGGSTRERTHATVARIIGEAGLPAAAHLTCVAASKAEIREVAEQYWDAGVRHIVA
LRGDAGEPGAPFTPHPEGYASAAELVAGLKNIADFEVSVAAYPETHPDALSPQDDIDNLK
RKLDAGASRAISQFFFSAETFFRFRDQCAAAGIDAPILPGILPVTNVAQARKFAGACGAA
IPAWMDGLFEGLDEKPAARHLVAATVAAELCRRLYAGGVRDFHFYTLNRPELAYAI
>A0A0F5IX02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. HGS0025|TrEMBL
MKVIDLINGSKATAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQNTEMYHEHATDLQEQVNNFNKGIAVDGSTFEANETPFSYGMACYPE
KHEEAPNMDSDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVDRCRAEGITVPIIPGIKPV
VFKNQLTVLPKIFRSDIPEPFATELRKCKNDDEVKAVGVEWCIQQCKDLVAHGVPSLHFY
TMMATDSVYKVAKEIY
>A0A1F0A127|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC061D10|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQDLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDLIPDVEPQKDFRYATD
LIEFIKEQAPHFEIIGACYPEGHPDSPNQISDIQNLKRKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQSLG
>A0A0M2GWB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces variegatus|TrEMBL
MALGTASIRSDHARTVRDMLAAGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLERIGSLTNAAF
PAALKERILTAKDDPAAVRSIGIEFATEFCAQLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSPQA
>A0A139H7N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudocercospora eumusae|TrEMBL
MAPAAIVSDLATVAHQPESNLTQANAPSPNLFSLSGQTIVVTGGGRGLGITLAIAVVEAG
GNVACLDVLPEPSAQEWSQLQSLAKKSGLTATYGKCDITQESQVQAVLEQISSAAASRNT
PFSGIIACAGIQQKTPVLEYPVEDFTRMLNVNVTGTFLTAKHSAKLFVQNNIKGSIVLIA
SMSGQVANRSLDCTAYNTSKAAVHQLCRSMAQEIGCHGIRINTLSPGYIRTAMTDALLKQ
EPEIEKTWMAGALLGRLGAPEDFKAPAVFLLAPGIQLPHPYRALRYTNSFDHESAMHISE
KLAAAHAKGQHTCSFEYFPPKTAQGVQNLYDRMDMMHALGPAFIDITWGAGGRHSSLTCE
MVKVAQSAYGLETCMHLTCTDMERSKIDHALEEAYKAGCTNILALRGDPPREQEKWEAKD
GNFRYALDLIKYIKKTYGRHFDIGVAGYPEGVDDTTNADEHIKYLKQKVDAGGTFIVTQM
CYDADIFIDWVKKVRAAGIPESVPIIPGIMPISTYAAFLRRANWSKARIPPEWLEVLEPI
KNDDSAVRDAGCDLIVEFCRKLMDSGIMHMHFYTMNLAAAVRMVLEKLELTPPAESPHPD
IKPLPWRQSLGLNRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFGSLDEY
GIGLKGTNENNRKIWGEPKTIKDIVSLFVGYMRGKVESLPWSEAPINEEANTLVDDLVAL
NSRGLLTINSQPAVDGVKSSHPVYGWGPRNGYVYQKQYLEVLVSPDLIGTVIQRMEQDPD
ITYYAVNCNGELKTNAPTDGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYHLGVEW
SKCYEEGSESRKLIKEITQSWYLVNIVHNDFRQQRGIFPIFDGLKVPGLDEVPYTNGVSS
VNGINGHGHIHEKLEANGVPDGNNVVNGADKASSNSTLKN
>A0A2H0DA25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium CG22_combo_CG10-13_8_21_14_all_37_15|TrEMBL
MKSFRERLGNELILFDGGTGTYLYEKGIYINRCFDELNLTNPELVTEVHCDYINAGADII
ETNTFGANSFKLTPHGLGNKVYEINLRGAKLAKTAAKESVLVAGAVGPLGVQIEPLGKLS
FDEAKDVFKEQIKGLLDGGVDLIVLETFALVKELIQAIRAVRELNADIPIVAQVTINESG
TLLSGAPLERFIEKLKDYPVDAVGLNCSVGPKAMLDALENLRSLTDIPISVQPNAGLPQN
ISGRNIYMTSPEYMAEYAKRFIQTGANIVGGCCGTNPTHIKAMRKAVQALQPVKKMDVKI
ADLQVEKPSEIKIYEKNEKSRLSNKLLKKEFVKLVELVSPKGVSPSREVDKARKLYHAGI
DAINIPDGPRASARMSALALAAIIQKEVGIETVLHIACRDRNVIGMQSDLLGAWALGLRN
ILAITGDPPKLGNYPDATAVFDVDAIGLTNIINRLNHGLDIASNPIGDPTGFCVGVGVNP
GAINLDEELKRLEWKIEAGAEFMITQPVFDIKLLEHFMKRIEKIKLPLICGIWPLVSFRN
AEFMNNEVPGASVPQKILQRMKKMTTKEEGFNEGVKIARETFDQVKTFADGVQISAPLGR
IEAIFDMIE
>A0A6J2ELT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zalophus californianus|TrEMBL
MDHPTPKVLPARPRGPSLGMWALETGRVRFSVPPSISRNPAMVNEPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQEQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGVTCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYLS
GEPNQHGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLSRPTPERGEEALGSCTVVSLP
>M1C552|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solanum tuberosum|TrEMBL
MKVIEKIQESVKDDRVVFSFEFFPPKTEDGVDNLFERMERMVSHNPSFCDITWGAGGSTA
DLTLEISNRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPATGLATLETYENELAYLK
QKVDAGADLIVTQLFYDTDNFLKFVSDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTR
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKIMASGIKTLHLYTLNMEKSALAILMNL
GLIEESKISRPLPWRRPTNVFRIKEDVRPIFWANRPKSYISRTIGWDEFPHGRWGNAKNP
SYGALSDYQFMRARSRDKKLQEEWAIALNSVEDIYERFMNYCLGKLRSCPWSELDGLQAE
TKIIDDHLGNINSKGFLTINSQPSVNGAKSDAPLVGWGGPGGFVYQKAYLEFFCSREKLN
AVIEKCMAFPFLTYMAVNKKGNWMSNVNQVDVNAVTWGVFPAKEIVQPTVVDPASFMVWK
DEAFEIWSRGWAQLYPENDPSRTLLEQVQNSYFLVSLVDNDYINGDLFAIFKDMIWN
>A0A0Q5AU90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. Leaf294|TrEMBL
MPFSFEIYPPRTTEGTAALLRTVDRLTEARPSFISVTYGAGGSSRSASLEILRHIHRSTS
VEALAHLTCVGSTHAEASRLVHEFLEAGVTRFLALRGDPPVGSPDGVDVVGDFGSAAELV
QLIHRVQAEREPYGAVAVPGQPNAQRVDVAGRPRAQVAVAAFPNGHPRSRSRTQDLDALL
AKEAAGASFAITQLFFHPSDYVHFVERARAAGVRMPIIPGVMPVTSPARLRRMLELSGED
LPAELAIALDVEPDDDARRRIGVAHAAAMVRTLVAAGAPAIHLYAFNRHEEALAVLAESG
LLPREPALAGGPRPSPPLTTERAS
>A0A2K8VZF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya solani RNS 08.23.3.1.A|TrEMBL
MSFFHANHQEALNQNLAELQGQINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRNELKAIAQDYWQSGIRHIVALRGD
LPPDGGKPEMYASDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRSELSYAICHTLGVRPVTAA
>A0A552DAS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa Ma_QC_B_20070730_S2|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGSLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPVHN
>A0A1H0TQG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus singaporensis|TrEMBL
MKEIRTNSRLEKILKNGHIAVTSECGPPRSSDAAVVVEKGHLIKDHVDCINITDNQTSVT
RLCSLASCIHLKNEGLEPALQMVVRDRNRIALQSDILGAASFGINSVLCLSGDHQSFGDN
PSSQNVFDLDSMQLIQTVRHMRDEGKFLNGDEIKVPPKIFVGAAANPFADPFKIRVPRLA
KKVAAGAEFIQTQCVYNLDKFEEWMKGVVDRGLHEKVYILAGITPMRSVGMAKYMARAVP
GMDVPQEIIDRLSGVPKEKQAAEGITIAVEAIERLKECTGVSGFHIMAIEWEEKVPEIVE
RAGLYPRPAVD
>A0A1G3BIK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RIFCSPLOWO2_02_FULL_50_16|TrEMBL
MIAGSNLERLLRAGKFVVTAELGPPNAADRTVVEKKAALLKGYADAFNVTDCQTSVVRMS
SIASAVILMEAGLEPVVQMTCRDRNRIGLQSDLLGAAALGMKNLLCLTGDHPKFGDHPTA
KPVFDLDSVQLLHMVKTMRDEKRLLSGTEIAVGPRFFLGAAENPFAGTIDIRARRLAKKM
AAGAEFFQTQIVYNVEKFTAWMKAVRDMGLHKKAFILAGVAPLKSPGMARYMKQNIPGMD
VPDEIIARMKEKKSKEEGIQICLDIIEQLRDIEGVAGVHIMAIEWEEIVPEIVERAGLLP
RPAPESFRNPV
>A0A2N7DI63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 10N.286.49.B3|TrEMBL
MGYTHAGHIDALNQNIAELSDDINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASRDELIQIADDYWANGIKSIVALRGD
IPPGGGAPDMYASDLVELLKGRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRTVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAQQFE
GLEDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPE
>A0A328UMY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogeniiclostidium mannosilyticum|TrEMBL
MDLSTLFRVKKVVFSLEVFPPKKDNPVHVIYNTLLGLRGLPADFISVTYGAGGSAVQQSK
TCEIASLIRSNYHIEPVSHLTCVNARKDKIIETLNTLKENGVQNILALRGDLPAGEENRS
DFVHASDLAAFIKSYDASFNLVGACYPECHYESQSLEADIENLKYKIDSGVTHLITQLFF
DNQRFYEFINKVRQAGITVPIQAGIMPIVNKNQIERTISMCGASIPTKLATIINRYSDNP
AALRDAGLFYATEQIMDLLENGVQGIHLYTMNNVQTATRISTAVESIIAAKNSANEA
>A0A174AJZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalicatena contorta|TrEMBL
MKIKDRLNENRIHISFEVFPPKTDAGYEKVQEATDRIAALNPDFISVTYGAGGGTSKNTA
KIAEHIKEDLGIESLAHLTCASSTKDEVRSVIGSLKELGIENILALRGDIPADMQFPSED
RFHYAYELVEEIRKHGDFCIGAACYPEGHVENEHKADDIKYLKQKVDSGVDFLTTQMFFE
NDIHYNFLYRIREAGITVPVLPGIMPITSAKQMKRSCELSGTVFPRRFQAILDRFGDCPD
AMEQAGIAYATDQIIDLLANGVRNIHIYSMNKPEVAEAIMSNLSEIIKC
>A0A424YIY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium sp. MSAO_Bac5|TrEMBL
MKIKKLFAEKKVVFSLEVFPPRNDVPIEDIYQTLDELQDIDPDYISVTYGAGGGLNKNRT
VEISSLLKEKYGIESLAHLTCINSTRKTLNQILDNLKAKNIENILALRGDHPDDGKEIGD
YTYAYQLVDHIKQKGDFGIAAACYPEGHLESDSLEEDLIHLKQKVDHGVDYLITQMFFEN
ELFYKFRDKAAAKGIDVPIEAGIMPVINKRQVSRIIELSDAYLPKKFTKILDKYGDNDQA
LRDAGIAYAVEQIVDLIASDVDGIHLYTMNNPYVAKKIKAAVGSLIDYINVEKAD
>A0A5P9F2F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbulbifer sp. THAF38|TrEMBL
MKNPIRISFEFFPPKTPEGRAKLYKTREALQAFNPEFFSVTYGAGGTTRETTANIVTSMR
KDGISIAPHLSFGGDNEETILGLLNTYKEADVNRIVALRGDMPSGMGAVAQLVYANELVA
FIRRHTGDHFHLEVAAYPEIHPESNSYDDEIRYLKGKFEAGANSAMTQYFYNPDSYFYFI
DQCEKAGIDAPIYPGIMPIINFDNLVRFSRNCGAEIPRWLKKRMESYRNPDDIRKLGLEV
VTDLCETLLEGGAPGLHFYTMNQVGASESILKDLGLKAR
>A0A662P8C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermococci archaeon|TrEMBL
MKTNSRLEKILESGKFAVTAEIGPPKSADAEVIRRKARALKGYIDAFNVTDGQTAVVRMA
SWAACLIGKEEGLDPIVQMTCRDRNRIALQMDILGIAALGINNILCLTGDYVSMGNHPSA
KPVYDLDSIQLIKTVKDMRDDKKFQCGEEMDVEPRLYIGAVANPFAGFPLELEVLRLEKK
VKAGADFIQTQCIYNIEKFERWMELVRERKLHEKVHILAGVTPLKSYRMARYMRENVPGI
DIPDEVLERMKSAPKGEAKEKGIELCVETIERLKEVEGVHGIHIMAIGWEGIVPTLVKKS
GLLPRPSL
>A0A843CN97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinaceae archaeon|TrEMBL
MSSDAVCERQEASFREKLGSRQFVITGELTPPVGTDVSKTLGNGEIIRDFVDAVNVTDSQ
CAVMHMSSVAFSHLLITKNYNVIMQMTCRDRNRIAIQGDLLGAAALGIQNVLIMTGDHPS
AGNNPGAKPVYDLDPVQVLETITKMKNGCDIRGAPISGSFDMCAGCVSNIDPDNMHMMKL
HKKVRAGAEFIQTQAIYDIDKYDEFLELLSDEGIDVPVIGGLVPLRTLKMAEYMDRSIPG
ITIPEDIFDRMRNAEDQEEEGLRIAVETVRELKKMCSGVHIMPIGCHANTKRILEGAGLL
RDSRKTDTVMQEQSL
>A0A3A3DJ68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. JM45|TrEMBL
MTRKDPKISFEFFPPKTLDASFRLWETARALAPLSPEFVSVTYGAGGTTRKLTHEAVTTI
NRQFGLEVAAHLTCVEATREETMAIVQDYADAGIREIVALRGDAPKGADKFTAHQDGFAN
SVDLIEAIAARGDMNIRVGAYPEPHPESADTDTDVAWLKRKIEAGATSAITQFFFDADTF
FRFRDKCVAAGINAPIIPGILPIQSWAGTKRFAAMCNTSVPDWAHEAFDLAALDGTEAQR
ELSTGICVDLCEKLIAGGVDRLHFYTLNRPDLTRDVCAALGVRPKATLEAVA
>A0A7Y2M3X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas fimi|TrEMBL
MSAPTVSPAGTVPDEALGTRTVSRRATGPHVAAVDRPLAAVDRPTVSFELFPPRNPGAAP
RLWDTIQHLADAHPDFVSVTYGASGSTRQTTRALVRRLLRETSLNPIAHLTCVGTSRAEI
TAIVEEFLDEGARSFLALRGDPPAGQPDWQPHPDGLHTASELVELLREIESRRCAGSPSQ
AVRARVRPLSVAVAAFPRGNAATGGTRAQDVASLLAKQEAGADFAITQLFFDAEAYLGLV
AEARDAGVTIPIVPGIIPATDPARLLRVQDLSGVPVPRDLLDLLGSADDDVERHRRGVRY
GVDLVRGVLDGGAPGVHLYTFNQHHAALDLLEGAGLDGGARTGRQAAPDPTSPDPTHEGQ
TPR
>A0A6P0SDK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symploca sp. SIO2D2|TrEMBL
MTKPTHNSFRAAAQSGEFLITAEIAPPKGGNPDHMVKMAQALKGRVHAVNITDGSRAVMR
MSPLAASVILLQYGIEPICQVACRDRNRIGLQADLLGAQALGIHNILALTGDPVKAGDHP
DAKSVFDLESVRLLKIITQLNQGLAANDKPLTDGATDLFAGAAVDPQLKSWSGLQSRFER
KIEAGAQFFQSQLITDFERLEKFMDKIAAGTDKPILAGIFLLKSAKNAQFINKYVPGVNI
PQAIIEQLANAANPLQEGIKIAAEQVKTAGQICHGVHLMAVKREDLIPQILDLAGIVPLN
EAN
>A0A6I4M8T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingorhabdus profundilacus|TrEMBL
MQEASRALADPLFAGLSGDCEISFEFFPPKTEKMEEQLWESVVTLAPLAPRFVSVTYGAG
GTTRERTHNTVARIAKETRIPAAAHLTCVDASKAEIADVANAYWQAGVRHIVALRGDAPN
ADGKFIPHPDGYASAAELVEGLHKLHPFEISVSAYPETHPEAASPATDIDFLKRKLDAGA
SRAITQFFFEPETFFRFRDAVAAAGINAEIVPGIMPVSNFSAITRMSNMTGTAIPAWMAH
LFEGLDDHPPARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLGKRPVPA
VQEKAA
>A0A1H9X6D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipaludibacillus aurantiacus|TrEMBL
MGFREDLKRDILIGDGAMGTLLYQQGADGCFEELNLTDPEKIRAVHARYIEAGADIIQTN
TYAANSLKLSRYQLEGQMEQINIKAVEIARDAAADHTYVFATIGGIGSIHHKEFHQEEIF
SSLKEQTDVLLRTDIDGFLLETFYDIEELIQLVKYIRSRTDKPVVAQVTLGDIGVLQGGI
ALTDGLKRLEEAGADVAGLNCRMGPYHMLRSLEEVPLLEEASLCVFPNASLPNVRDGRFF
YQSNPTYFGDMTESLVREGVRLIGGCCGTTPEHVQAIREAVDKKGLKPVTEKVVKEKETP
SVVVNAPEPPERLPDFSKNRKSVIVELDPPKALSKAPEFMKGAQALKDAGADAVTLADNS
LASARIDNLSLGSLMKQQTNARPLLHVACRDRNMIGLQSHLLGMHTLGIHDVLAITGDPA
KVGDFPGASSVYDMASLDLIRLIKQLNEGISFSGKDLGAKTSFTVAAAFNANARRLDREV
KRLEKKIEAGADYFMSQPVYSVEQFKEIHEATKHLPVPVYVGIMPLVSSRNAEFLHHEVP
GISLTQSVRDSMAKHGGDREASQREGIALAKELTDAALEYFPSIYLITPFLRYGITAELT
RHIVEKDQPVTIQAPDRTNI
>A0A8J7VJS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lawsonibacter sp|TrEMBL
MKIAELFGKGKTVFSCEVFPPKKDSPVDTIYQTLDGLKDIKPDFISVTFGAGGSQVNQST
REIAAIIQKQYHIPAMAHLTCITATRGEVTELLYDLKADGVENVLALRGDRNPDYPPKTE
FLHADELVAFIRRRGDFGVSAACYPEGHPESPDAVSDLRYLKQKVDAGAQHLVSQLFFDN
EDFLRFLERARIAGITVPIEAGIMPVLNQKSIERMVSLCGASIPRKLSRILARYGDHPEA
LREAGIAYAIDQISDLVAAGVDGIHLYTMNNPAVARQISDSVSAIRRV
>A0A7U3PQV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio europaeus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELIQIADDYWANGIQSIVALRGD
IPPGGGKPEMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPTA
>A0A412GSA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola coprocola|TrEMBL
MRVIDLIKSPEKTAFSFEILPPLKGTGIEKLYETIDSLREFDPKYINITTHRSEYVYREL
GNGLYERKRIRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREDTEYVLLDLQFLGITDL
LILRGDKAKHEQVFTPEPGGYAHAIELEHQINDFNQGVFVDGSPIKTPVHPFSYGVACYP
EKHEEAPNMEQDIYWLKKKVEAGAEYAVTQLFYDNRKFFEFVDRVRQEGIDIPIIPGIKP
FSKLSQLSVVPKTFKVDLPQELALEALKCQTDEETHQLGVEWCINQCRELIAHGVPSIHF
YTVGATESVRRVAKEIY
>A0A7W4H2W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas guryensis|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVKVPTAPHLSCVGDSKEELRSLLQQYKNSGIRRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKAKAGANSAITQYFFSADCYFY
FVERVRKLGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDLQSIQGFG
EQVVSEMCERLLEGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A836CIM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tribonema minus|TrEMBL
MDTQEAPAESLPGSKISDLIAAAQELRKPFVSLEFFPPRTVAGVVNLRERIQRLKRVAPF
FIDFTWGAGGNTADLTLDLVLEAKLEHGLEPNMHLTCTNMPVLKIDNALQACREHGVRNI
VALRGDPPAGENQWLASEGGFKCALDLVHYIRQQHGDFFCVSVAGYPEGHPDRIRQRKGG
LDALSEAERARCSVSPGTGEVYVCSDKDFEVELAYLKAKCEAGADVIITQMFFDASVYGR
FVAECRRVGITQPIVPGIMPINAYGGFQRMTSFCRTRVPPNLLARIEVNKDNEAAIKEIG
LDYGEQMCRELLQLGAPGLHFYTLNLEKVTVGILRRMGLAGDYDEPPTEDTAQMLDMIKS
G
>A0A8B6LRV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. SRS16|TrEMBL
MPFMRTANQEPAVRLPLSFEFFPTKTPEGAVKLRAVRQQLYAQKPEFCSVTYGAGGSTHA
GTFGIVGEILAEGVDAASHFSCIGATRETVRAQLAELKAMGVRRLVALRGDLPSGYGIGG
EFLYASDLVRFIREETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVHAGADSAITQYF
FSAEAYFRFVDDVRKLGLAVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDD
TASIRAFGLDVVAALCERLCAGGAPALHFYTMNQSVATLGVLQRLGWSE
>A0A5N6IGH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus pseudonomiae|TrEMBL
MFPFPLIGGPVKLRPKPFPPRWISPQSSFFNYHPSRTFVGTDSGNKMEKITDKIAALPPD
ANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGSTAQRSLELAEICQRQ
LQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYSMHGEDDSNKDFT
FAVDLVRYIRQKYGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTQAGADFIMTQ
LTYDIEAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVQIPPQILSEL
EAVKHNDDSVKRIGVDIISNLVDGMRDIPCPGIRGFHFYTLNLEKTVSFILERCDLIPPY
SEDFDAIEDGEEISAMDGAQLRSLTRRRASSINSLPHNRVIVDKLHASEVSSKASISHEA
PATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLH
VPPSVAHRIWGFPVSREDISALFRRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELL
QLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLL
QKHGHEKLAWFATNAKGDFESSLPAQTSDADPIEMNPNNVNSVTWGVFRGKEIVTPTIIE
EVSFRAWGDEAFGIWDEWRSIYPRNSATERFLNETKDDVWLVCVVGQDFGAGTEMGSEEE
EDEKKFMWRVLLNAK
>A0A1Z8X7N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED78|TrEMBL
MIGLSFEFFPPKDQNMNKRLLGCLSELSVFLPKFVSVTYGADGSTRDRTHNIVKKIAEET
SLVCAPHLTCVGSNKEKLITIINSYWDQGIRDIVALRGDLPKYDTSMKRGNEFSHAVELV
DLISNLNSFNISVAAYPEVHPEAKNAEEDIDYLKKKIDAGASRAITQFFFDVDIYLRFRD
RCKNSGIEAEIIPGILPINNFDSMLNFSEKCGVSVPKYLFEKFLDKKIDNETKKNISIDY
CKKQIELLSKAGVKNCHFYTLNKSELISKILEE
>A0A5C6UFL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas ginsenosidivorax|TrEMBL
MSISITQLGEARRALEEPLFADLAGDIGISFEFFPPKSEKMEAQLWDAVRTLEPLAPDFV
SVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIVA
LRGDMPTLGQPYQPHPGGYENAAALVAGLTRLHPFEISVAAYPECHPESGGHDADLDNLK
RKLDAGASRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGACGAE
IPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHML
GVRAKPAAEVAAA
>A0A238WHW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes regularis|TrEMBL
MSLGLPSKLPGTPSIGELIRGAAPTFSFEFFPPKTPDGERLLWQAIRELESLRPSFVSIT
YGAGGTTRETTVAVTERVATETTLLAMAHLTAVDHSVADLRNVIGRLAGAGIRNILALRG
DPPGDPMGEWVRHPRGVLYAEDLVRLIREAGDFSVGVAAFPYKHPRSADVADDTRNFVRK
CRAGADYAITQMFFDADDYLRLRDRVAASGCDTPIVAGVMPVTRMATIERSTQLSGAPFP
PALLRRFEAVAGDEAAVRELGLEECSRMCARLLDEGVPGIHFITMNRSTATREVWQRLAP
SDVAAAV
>F7S7U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiphilium sp. PM|TrEMBL
MSHTPPRAVLERWLSGPRVDPLPTPALRAPAPAISFEFFPPKTETLEAQLWACIRRLEPL
APRFVSITYGAGGSTQERTHATVTRLVRETTLVPAAHLTCVGASRGEVDDVARRYWDAGV
RHIVALRGDPPGGTAYAPHPEGYAYAADLVAGLRRVADFEISVAAYPETHTQAPSPQADL
DNLKRKLDAGATRAISQVFFETGHFLDFLDRALAAGITAPIIPGIMPVSNFGQAKRISEM
AGTHVPAWMGEMFDGLDDDAETRKMVAASIAAEQVRTLQANGIDEFHFYTLNRADLTYAI
ARILGVKPAR
>A0A2S4SMW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae complex sp. ECNIH11|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A8C6E593|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moschus moschiferus|TrEMBL
MVNEPRGNGGPGPRWEGSSSGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSRDEITGHLHRAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKH
IRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQRIRDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQDERETAAA
>A0A1F9IQJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFCSPLOWO2_12_FULL_43_16|TrEMBL
MHTLKDSLSSKKFTITAEICPPKGTDVSDFLKKAQLLKDKIAAANVTDNQRAVMRLSSLA
CSVLLLKQGLDPVFQMTCRDRNRIAIQSDIMGAWTLGVKNILALSGDHVSFGDHREAKAV
FDLDSVQLVQVINKLNSGTNMKETPLKGGTGFFIGAVVAPEAEPWEPEMIKFEKKIEAGA
RFFQTQAIYDIDKFHKFYEYARKFDVKILGGILLLKSAKMAHFLNTNVPGVTVPKHLIDE
LEKAKDQLEKGIEIAARQVKELKKFCDGAHIMAIGQEESVVKIIEGAG
>A0A1Q3S973|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 40-81|TrEMBL
MKVTQHIENAQGKSLFSFEILPPLKGQNIQCIFDNIEPLMEYKPPFIDVTYHREEYEYKE
LPNGLLEKRIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDMDFLGIDN
VVALRGDAVKSEIYFKPEKEGNHYASELVTQISNLNKGIYLDDHLQNTNKTNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIHNGADYIITQMFFDNRKFFEFVAKCRKEGITVPIIPGLK
PISTKKQLNQIPHRFKVDLPDDLIMEVVKAADNEAVKQIGIEWCIEQSKELVKAGIPVLH
YYSMGRSENIKQIAEAVF
>A0A200J8Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus sp. 9D6_DIV0238|TrEMBL
MRTDALFKEKTVFSFEIFPPRRTAPVETIYHTLERLKGQQPDFISVTLGAGGTGNNLSTA
DIAQKIQEEQFLPSVAHLPAVNFSKNEVIAILDELKQKKVENILALRGDILPDKEPKKDF
VYANDLITFIHEQGQFNIIGACYPETHSDAASSVEDIQNLKRKVDAGTNQLITQLFFDNH
YFYTFKEKCEIAGIDIPIQAGIMPVVNKKQIERMVKMSNVTLPTKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVAQGADGIHLYTMNNPYVAQKIREATRSLFEA
>A0A1E8TPU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC065C12|TrEMBL
MTTVHPALSFELFPPRSHASCESLIRTIAELEGTNPDYVSVTYSGDAKRRQKTLALLDYL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDVQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMSVPADLAYALETATSSAE
LHRIGVDYALNQCRTVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEF
A
>A0A380LNZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalicoccus pleomorphus|TrEMBL
MKISEILKQDKVTLSFEVFPPKKIDDYSKVEAAAKKIASLHPDFMSITYGAGGGTSQYTV
DLARDLYQKYGTQVIAHLTCVSSTREHVLDMIQKCKDAGIENIMALRGDIPKDGLIAHDY
QYASQLIQDIKAQGDFCIGGACYPEGHIECEHKKEDILHLKEKVDAGCDFLTTQMFFDNN
IFYNFLYRIREAGIQVPVLAGIMPITNKKQLARSVQMSGTQVPERFKAIVDHFGDDPKAM
EQAGIVYASEQIIDLIANGIRHIHVYSMNKPDVAARIQANLSEMIK
>A0A1V6B9N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin145|TrEMBL
MSVIEKIKNAKGPLFTFELLPPLKGHSIERVYSAIDRLVEFDPAYINFTSHRDEIIYSER
PDGLLEKKIVRKRPGTIALAAAVKYKYNLTVVPHLLCGGFSREETENVLIEMNFLGIDDV
LALRGDPQKGSRTFIPEKDGHSHTSDLVKQIINMNNGKYLEELLEDTTPTSFCVGVAGYP
EKHNEAPNRHVDLENLKLKVDSGASYIVTQMFFDNSKFFRFRDECKAIGINVPVIPGIKP
ISALNDIRMLPQTFHIDVPNDLVNAIKKCTTDKDAREVGIEWAIMQSKELISKGVPGIHY
YTLGRSDNVARIVRASF
>A0A2J6IZB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MLMSRLQEELAAGRFTVTAEVAPPKGIDLQNVLDVAAAFSGVTAVNVTDNQGANMRMCPL
VVAGKLVDAGIEPILQLTCRDRNRMALQSDILGAAALGIENLLLLSGDHARFGDHPEARS
VFDLDSVQLLQAVNDLQQGVDMVGRKLDGVPIFFPGAAVSPESEPFELMFQKFRKKIDSG
ARFFQTQAVFDGGRFEQFMAEAREVGTPVLAGILLLKSARMARFLNDNIPGVRVPEKHID
RLEKAGNPLDEGVAIARELVGVARSCCQGVHLMTLGHEDRIPEILDN
>A0A2N6EZ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MKKPSNPLTSKQTDNQLELAVATPLPQDVQVSFEFFPPKTEQAEIDLWTAIKRLEPLQPA
YVSVTYGAGGTTRERTHATVSRLRRETSLEPAAHLTCIDASRDEIDEIARQYWDEGVRHI
VALRGDPAEGQQRYVPHPQGYAYAADLVSGLKQVADFEISVAAYPEGHPEASNPEADLDN
LKRKIDNGATRAITQFFFDTEIFLRFLDRARAAGIEVPIIPGILPVTNFARVKDFAAMCG
ATIPLWMADLFEGLDNEPETRKLVAATVAADQCRALYAHGVNAFHFYTLNRADLTYAICH
ILGVRKKND
>A0A372DU06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnothrix sp. CACIAM 69d|TrEMBL
MPVLSRFRTAASAGTFLVTAEVMPPKGSDASHMLAMAEQLQPWVHAVNITDGSRAVLRMS
SLAAASLLLQRGIEPVWQVACRDRNRIALQADLMGAHALGIQNVLALTGDPVKAGDFPEA
RSVFDWEAVRLLEAVKRLNQGQDAADRPLENSGTDLFVGAAVDPQCKSWSGVQRRFQRKL
AAGAQFFQSQLISDFDRLDQFMTQVAAGCGKPILAGVFLLKSAKNAEFINRNVPGVEIPQ
HLIDRLARAQNPLREGMAIAAEQVAMARQICQGVHMMAVRREDLIPEILQMAGLEPVTLP
AQPIDSNGQTNGHAHSRPNNHSDSPLGSQPTDQATDQITDQTTGQATGNSSSPSFTPTSP
LHP
>A0A2N6F3P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MSRFADLLISGNFVVTAEIAPPKGADATAALAVADKLHSVDAINITDNQGACMRMSPLAL
ARLLIDRGFEPILQLTCRDRNRMALQSDILGAAALGVENLLLLTGDHPRFGDHTASRPVF
DLDSVQLLQAVTQLQDGIDMAGNRLASIPRLFVGAAASPAADPQDLALKKVQKKIACGAQ
FFQTQAVFQRSRVELFMETAQTYRVPVILGVLLIKSPRMARFLNAQIPGVRVPDELLERL
DNARDPLCEGIEIAREMVSWAREYCQGVHLMTFGREELIPEILG
>A0A3D3GIQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MKISQIFAQKKQSFSFEFFPPKTPEAEEQLYGAVADLKSLKPTFVSVTYGAMGSTSSNSI
RIAERIKTKLGLEVASHLTCVGNTKQEIEKVLSEL
>I4E699|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis alpha522|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A3P7S0B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrocella atlantisensis|TrEMBL
MMIKDYIKEQVLLMDGAMGTYFAELTEGHYTLSEPANISKPGLILDIHRAYIEAGAKLIR
TNTFAANPYTLYRSFDEVKKIIIAGIDIANEAVKGTDCYVAYSIGPIGEPYDIEDYEIES
TYRKLIDIGLLKNVKIILLETFSRIDQVNQLVEYIHEHGPNIQIMTNFTVNQHGYTKVGV
NKEKIIQQTRQQDLVTTYGFNCGIGASHLLSLIKTLDFDPSKMAAVPNAGYPDQQLERTV
YQSNADYFADTMIKICEEGVRIVGGCCGTTPDHIRKIRERLYTLDFGEVKSISRMKRKSL
PLKPLHNSFREKLEKNEFVVAVELDPPFKMDMSLIISSAHLLKEVGVDIITFADSPLGRT
RADALLVAAKIKQLTGMEVLPHVCLRDKNLIALRGGLVGAHLSDIRNILIVTGDPIPSDD
RDEVKSVFNINAISFMQYVTEINSELDKDTFYIGGALNPYSQNMDITIERVLKKKEAGAS
YLLTQPVYNEAGIEAIKKVRDRTGIKILGGIMPLVSLRNARFLHYEFPGIIIPDDVMSKF
DDTMTKEEAEKVGVELAVTLAKKMKPHVDGLYFMTPFNRATMIEKIIKKLDVR
>A0A7Y4QWS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MKVIEHLEKAKSKHKPLISFEVIPPKRGGDITQLFNVIGDVMKYEPPFIDVTSRAAEVEY
RETPQGIQKKVIRKRPGTIGISVAIKNHFNIDTVPHILCLGFTREETEDALIELNYLGIE
NVLAIRGDDLGYHKPIPEYKSQNRFAYELINQVNNMNKGKYLEDDLLDAKPTNFCIGVSG
YPEKHFEAPNMKVEVDHVKQKIANGGDYVVTQMFYDNKVYFDFVNKCREAGIDVPVIPGL
KVITTKNNLYTIPKNFYINIPEELSGEILEAKDEHVMEIGAKWTAKQAEELLNNGAPSLH
FYIMQSAKPINKMFGHLKM
>A8SCX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii M21/2|TrEMBL
MKSFYRKGKVSMLDVRKLLAQRPLLFDGGMGTYYKAKPGQECEQANLTDPEGILAVHRAY
LAAGADAIKTNTFSLPRLAAAQQPGWEQLADAGWQLAVKAAGETGAAVFADLGPAPDTEN
LPAEQVYLAVAKRFALLGARNFLFETLSAEDGVLEAIRALKQTVPEAFVLVSFAVLPDGY
TREGRYCAELVRRVAQSGVVDAVGLNCVSAPGAMRALVQQLGDAGLPLSVMPNAGYPVVA
RAQVRYQGKPEYFARELSRLASEGVRILGGCCGTTPQHIAALRTALDALPEVLPAAPAAK
PAVAAKPAVETDDAFLRKLRAGQRVIAVELDSPKDADLTAYLEGARRLQAAGADLLTIAD
CPIARARMDSSLVACRVHRELGMNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGD
PIPTAERDEVKNVYQFNSRKLAQYIVSLAGEGREMPSPITVFGALNLNARNFEVELRRAA
EKLENGMSGFLTQPVLSAQAVENLKKTRETLGERAKILAGILPVVSQRNAIFMENEVNGI
HVDDAIIQRFEGLDRAAGEELGLEVSVQAAKAAAPYVDGFYLMTPFNRVALMERLIARLR
TEVTG
>A0A7V1LGF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MKVIEHIEKAEKPFISFELIPPKRGGDITGLLNVLDNVVKYNPPFIDITSHSAEVIYDET
KDGIKKKVKRKRPGTLGICALIQHKYDIDSVPHILTNGFTREETEDFLIELSYLGIDNVL
AIRGDDHGFQKPVPKGKSVNQYASGLVKQINDMNNGKYLEENLLDAQPSNFCIGVGGYPE
KHFEAPNLHADIKYAKQKVDAGADYIVTQMFYDNKAYFKYVELCREQGINVPIIPGLKII
TAKSNLTSIPKNFYINIPEELSDKIMNAEEDKVLEVGVEWAASQVEDLIKQGVPSIHFYV
MLNSKPISMLMDRLKLF
>A0A3N4ZLD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TLI_185|TrEMBL
MLATGKTTFSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRAGTVKATEQ
IAADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWVPHPTGL
TYAAELVQLIKESGDFCVGVAAFPEMHPRSEDWDTDVARFVDKCRAGADYAITQMFFQPE
SYLRLRDRVVAAGCDTPVIPEVMPVTSVKMLERLPQLSNAVIPSALKERILTAKDDPTAV
RSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>A0A3D0ZAI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MKITELFKRGEFVVTAEVGPPKGFHIEHLLDEADQYLKGITAINVTDNQSSVMRLGSLAA
CVSLKNRGFTSIYQITCRDRNRIALQSDILSAAMFGIENLLLLTGDHTKMGDNPQAKPVF
DLDSVSLIHAVKTLESGYDLGGNELSGTPPSFAKGAVVSPCSDSVDAQLAKMERKVKAGA
EYFQTQAVYEPEKFFRFMEKAKQFGVPVQLGIVIPKSAGMAKFMNNNVAGISVPQEMIDE
LNADKEKTKAGITGVEISARIIRECKNYCQGVHIMALGWESKVPEILSLAGIAP
>G6C8B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. oral taxon 058 str. F0407|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFEIVGACYPEGHPDSPNQILDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2E2ZY70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
MVPAPAPSFPSGVSLRPRDALVEEIAQLTHGASYEIAARDTVALQEAAAHIAPGATISIT
WMPSDTHEDRVKATRAVREAGYEPVPHIAARRIRNEADANDLLARLADAGARRLFLIAGD
VPRPIGDFASSLELVGRLRKSLGAFEAVGFGGYPEGHPAIPDATLQSELETKIAVVEDAG
LSPFIITQFCFNAAPILAWLAALREHGSTVPVRIGLAGPASIRTLLRFARVCGVGNSARA
LAGNSASIARLLRETGPDPVIRKLAEAEVRKQSGPVALHFFPFGGLARTAQWVAPVTRGQ
IRLQPSSSGFQPLS
>A0A0F2PBM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium BRH_c8a|TrEMBL
MKTESKLQQILDNGQFGVTAEIGPPKHSSSEGMRHHAHMLKEHVDATNITDNQTAIVRLS
SIAAGVHILDSGIEPIVQMTCRDRNRIAMQSDLMGAYSLGMRNVLCLSGDHQQFGNHPTS
KNVYDVDSMQLIQLLRRMRDEKKFFSGEEIKEHEPRFFIGAVANPFADPFEYRVARLEKK
VEAGAEFIQTQCIFDMERFERFMEMVRARGIDERVHILAGVTPLKGWRAAKYIQNNVSGM
IVPEELVQRLKSAEDPKKEGVNICVEQIKYIKENIKGVHGVHIMAIAWEEVVPEIVERCG
LYPRPKIN
>A0A2T2SQ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QH_9_67_14|TrEMBL
MKVTERLESADEPLISYEIIPPKRGGSAEQIMGVVEELMPYDPAFIDMTSHAAEVEYVES
GDGTWRRRVMRKRPGTIGLCAAIEARYGVDTVPHLLCKGFTREESEDALIELNYLGVDNV
MALTGDDPGYKKDIAPSRSRNEYAVELVEQINDMNQGTYLDELADTAPTDFCVGVGGYPE
KHIEAPNLTWDVLRLKRKVDAGADYITTQMFFDNDAYFEFVERCRDVGITVPIIPGMKIL
SRKRHLQFLPSFFHLSIPEALAAEVEAADDKEEVERIGVEWAIQQAEELMDAGAPAVHFY
IMSSARLAKRVVEPLRENRRKKKGQQAPVEEQPAPEEQPAPEEQPAPVEEAEEVDE
>A0A259E7U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium 17-64-11|TrEMBL
MSARTYSFEFFPPKTSEGAEKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETVREIQA
DGSEAAPHLSCIGSTEASIRDILNEYKSQGIRHLVALRGDLPSGTMDAGEFNYANELVAF
IRKETGDWFEIEVAAYPEVHPQARSYAEDMVNFKRKVDAGANAAITQYFFNADAYFSFVE
DARALGVGIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLESYGDDLASIRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPSTVIWQRLGL
>A0A5P2GIM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Empedobacter brevis|TrEMBL
MKVTQHIERANGKPLFSVEILPPLKGQDVNATFKTLDPLVELNPAFIDVTYHRQEYIYKQ
KENGLLKRYQVRKRPGTVAICAAIQNHYKVDAIPHLICGGFTKEDTEDALIDLNFLGIDN
VLVLRGDPIKSEKSFVPEMGGHAHASDLIGQITGLNTGSYLDDELQESHPMDFCIGVAGY
PEKHFESPNLAMDLHYLKKKVELGADYIVTQMFFDNQKYFDFVNKCREMDIHIPIIPGIK
PLTTFSHLTSIPQNFYIDLPEPLSMEVLKAKDKEAVKQIGLEWSIHQCKELIEFGVPGLH
FYTMSNSNNTKTVAEAIF
>M6CY46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira alstonii serovar Sichuan str. 79601|TrEMBL
MKKISEIYGAAKGPVYSFEFFPPKTPEGDLKLMETVKELSRLDPDFVTVTYGAGGSTRDK
TVQILSEISKNYSLPTVSHFTCVGADRGQILETLKGIRSSGIVNLMALRGDPPKGEGEFK
KPEGGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVRNLKWKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGINVPVIPGIMPITSFSQIERFHSIAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGGSL
>A0A3D3FRH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MWIPRPAACAEYSEETGMKKHIENKTYHVEILPPKQDTEKLETDLENFSVKFNRVMESGY
CACLTDNAMGNLAFQGTEMIEELGLEPRKDLVMIHLNTFHTKGDLDRILDSCRTLKIRQL
LVISGDGSDRLPKLSPADVGATDTEAVTSVELLRYIGREYPGDFELGVAFNPYEPEEHEF
AKMERKLAAGAVFIITQPVIERHEVVDRLLAKYPGIPVIVEAWMSKKIDLLSEAVGYEIK
TATDPFDPIATLKILHKNYLGCGVYLSLLGFKTQYDLIKDTWQ
>C0D4X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] asparagiforme DSM 15981|TrEMBL
MKIRDILAAGKPTLSFEVFPPKTVDAYEPVERAACEIAKLKPAFMSVTYGAGGGTSRYTV
DIADTIKGYGVTPLAHLTCVSSTREKVHQVLDELKSRGIENVLALRGDLPADGETPREYR
YASQLIREIKESGDFCIGAACYPEGHVESANKSVDMDYLKEKVEAGCDFVTTQMFFDNSI
LYSYLYRIREKGITVPVIAGIMPVTNAKQISRITGMSGTYLPARFKAIVDRFGDNPAAMK
QAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAARIRENLSEIL
>A0A6N7TYA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium asteroides|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLMPDFISVTYGTGRRSDRTATARIAKTIH
TEYGIPAVAHLTAQYADREVIDQALDMFDDAGVAAVLALRGDSVEGREPAGVFDHASDLA
AYIRSRRPNLSIYGACYPETHPEAASPEEDIENLRIKVDSGVDHLVSQLFYDNADFLDFL
DRARAAGIQVPIEAGIMPITNEGQVRHMSEVCKARIPAAVESILERWGDDRASLREAGII
YASQQIADLVAHGVDGIHLYSMNHSGVTRRIWHNVRHLFRQAGAKEEPVSSHK
>D5E064|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia megaterium (strain ATCC 12872 / QMB1551)|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINVAGVKLAKQAAKDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLNEGVDGLLFETYYDFEELKTVLTLARKETDKPIITHVSLHDIGVLQDGR
PLADALKELEALGADVVGLNCRLGPYHMIQSLEEVPLPDCAFLSAYPNASLPAYVEGKLE
YETNEDYFVESARLFREQGVRLIGGCCGTTPAHVRAMSSALKDLPPITSKVVKMRPAVTV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRIRGEVEGLAIAKNLIDTAYELFDGIYLITPFMRYEMTEILTRYI
HDKQLVTSERKI
>A0A6P3B007|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MKTIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVV
>A0A8E1R5X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. tabaci|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A8D9RGH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mannheimia haemolytica PHL213|TrEMBL
MLWDSIDRLSPLKPKFVSVTYGANSGERDRTHSIVKSIQEKTGIISAPHLTGIDATPEEL
KVIAKDYWDSGIRRIVALRGDIPKGYDKALFYASDLVALLKSVADFDISVAAYPEVHPEA
KSAQADLLNLKRKIDAGANHVITQFFFDVESYLRFRDRCVSIGIDCEIVPGILPVTNFKQ
LQKMAAVTNVKIPTWMGKMYEGLDDDQTTRNLVAASIAMDMVKVLSREGVNDFHFYTLNR
SELTYAMCHTLGVRPDLTTA
>A0A2E0WVJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVIDYIKNSNKTIFSFEIIPPLKGKGIEDICEGIDPLMEFKPPFINVTYHREEYDYKKM
GNGLLKKISIRKRPGTVGICAALMNRYKVDAIPHIICGGFNKEDTESALIDLKFLGVDNI
LALRGDPMKNESSFVPVDGGNEFAIDLIQQIDEMNNGQYLYEETKNSPSNFCIGAAGYPE
KHFEAMNLASDLRHLKAKVDAGAEFIVTQLFYDNKKYFSFVKKCREIGITVPIIPGLKPI
TNQRHLTFIPKFFNTNFPEEFSNELEKCKTNEEIKKVGIEWSIEQSKELIDAGVPVLHFY
TMGKGQSVKEVASNIF
>A0A2E4EFM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MNVIESIEKSKGETLFSFEILPPLKGSHIDELFGRIDPLMEFNPSFVNVTYHREEYIYKK
RPNGLLEKQATRKRPGTVGICAAIKNKYHVETVPHLTCGGFTREETEDALIDLNFLGIHN
VLALRGDALKSDNRFIPDEGGHEYAVDLVKQIVNMNQSKYLSDELINPSPTEFCIGVAGY
PEKHFESMNLKTDLRHLKEKIDAGAEYIVTQMFFDNEKFFAFVEKCREMGITVPIIPGLK
PITVKNHISFLPKTFSIDFPDTLADELEKCSDNKEINEVGIEWCIEQSKELKKAGVPSLH
YYTMGKSETVRRIASAVY
>A0A414QIF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus comes|TrEMBL
MRIIDKIKADGVHISFEVFPPKTDAGFESVLKATDGIAELNPSFISVTYGAGGGTSKNTV
KIASHIKNDLKIPALAHLTCVSSTKEEVHKVIRQLQKEGIENILALRGDIPQDGQFPLPG
QYSHACELIEDIKKMGDFCIGAACYPEGHVEMEHKKDDIRYLKEKVDSGVDFITTQMFFN
NDIFYNFLYRIREQGIMIPVLPGIMPITTKKQLARSCALSGTAVPQRFRAIVDYFGDDPA
AMKQAGIAYATDQIIDLIANGVRNIHVYSMNKPEVAAAIMQNLSEIVK
>A0A1G0M3Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium GWC2_55_20|TrEMBL
MKIIDKIRPGNQFISLEFFPPKGHSEWPAFFQTVERLSGLDPLFASVTYGAGGSTHGDSL
EIVTRLQKEYALETMAHLTCIGSTPDEVKSFLDALAGAGVENVLALRGDIPQDAEAGFTP
SPLLGHASDLVSLIRSSHPALGIGVAGYPEPHPEALNPESDLAYLKLKLDNGADFAITQL
FFDNDLYHDFVQRALSAGVTKPIIPGILPVVSLKVIKRI
>A0A423IT42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas frederiksbergensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARHLATFNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>W8VIG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae 30684/NJST258_2|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A4R4JFI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus luminescens subsp. mexicana|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSIGRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLDAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGD
LPENSEKPKMYGSDLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQLKRFAVMTNVRIPSWMTRMFD
GLDDDPESANLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A6C0RIB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Draconibacterium halophilum|TrEMBL
MKVIDTINQAEKTVFSFELLPPLKGNDVSRLHKTIESLTEFDPKYINITTHRDEIEFKEL
PDGSIVKRTVRKRPGTVAIAANIQHKYGIPVVPHILCGGFTKSETEHVLIDLNFLDINNV
LAMRGDGLKSQHVFKPTVNGHSNARELVKQIKDLGKGKYLEEDLKNNKPLDFCIGVAGYP
EKHFEAPNMDQDMAFLKQKVDEGADYIVTQMFFDNQVYYDFVDKCRAMGITVPIIPGIKP
INLKNQLTVLPKIFSIDLPQELTKELAKCKNNDDARLVGTEWAIHQSKDLVAHNVPSLHI
YTYGISDNVNKIVKAAF
>A0A519IJ78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haliea sp|TrEMBL
MNLPISFEFFPPKTPEGAQKLRATRQALYAEKPEFCSVTFGAGGSTQEGTFATVQDILTE
GVDAASHFSCVGATRATVRQQLTTLQIMGVKRLVALRGDLPSGYGAGGEFQYASDLVEFI
RAETGNAFHIEVAAYPEIHPQARSADADLQAFATKV
>A0A062C1C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 263903-1|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKLVHQDLQHLNPEFFSVTYGAGGSTRERTLAAIEEFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQNIKRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIRRFIEKVNAGANAGITQFFFNPDSYFYFL
DRLAKEGIHIPIAPGIMPIINASNLIRFADGTGAEIPRWIRKQLSAYGDDSVAIKDFGHE
VVLKLCERLIAGGAPSLHFYSMNQTEPTRQLVLDLGLA
>A0A2S6S1C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha6_Bin4|TrEMBL
MQQNLKISYEFFPPKNVKMYQSLWSTLNKLKIFYPDFVSITYGAGGSTRQRTHDTIKKFT
YRPSIKPIPHLTCIGDTKDSIKRLAIEYWKLGIKSIVVIRGDPENIKLTKKRKFITHPNG
YTYASELIRDLKKIRDFDIIIAVFPEMHPESKDMKEDIDNLKRKIDLGATKGITQFFFDN
NKFYEFINILEKKKVKIPIIPGILPIINFKKLSELAANCNSSIPKNIQRLYKDKKKPEFE
LSVEIATKQCLDLIKNGFKNLHFYTLNRADLTGKICSNLTKKRMTQKPYDAFWS
>A0A6H1MYJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S1D4-11|TrEMBL
MDSVSTAAASAVAPLLDDFSLEMTGKDVPKLEEARDTIPQGTRINVTFLGNEDLDMRLAA
ARAVKRLGFVPVPHISARRLPSRAALEEFLAALEADGLADNVFVVGGDPAEPHGPYDDAL
ALIRSGLLQKHGVRHVGVSGYPEGHPAIADPVLWSAMEHKSAALEEHGLPGAVITQFGFD
VDAVLSWVEAVRARGIDLPVRIGVPGPAGIRRLMTYAARFGVGTSTSIAKKYGFSLANLM
GTAGPDRFIRALAKGYDARRHGELKLHFYTFGGLKTTSEWVADFRDKEN
>A0A7X8JVL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MLKDKILNKKSGIITYGFTPPKAANPPDKIKEISEKQIERIRTIDVDGLVIYDIQDEKDR
TETERPFPFLETLDPLMYSNEYLDALQLPKIIYRCVGKYTHNQFTSLIDADATKDMFSVF
VGAASKNQAVSLRLSEAYEICKTVNPRLILGGVAIPERHMKNKEEHLRILSKLQKGCKYF
ISQAVYNVEAAKDFLSDYYYYCRNNNIEMVPILFTLTPCGSLKTLEFMKWLGISIPRWLE
NDLMNSEDILNKSLSLSKDIFNELLDFSMEKGIPIGCNVESVSVRKVEIEASIRLVNDIK
SILKSNSL
>A0A7K0IZ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
MKIIDKIRQGSQFISLEFFPPKKHDEWPFFFNTVERLAELNPLFASVTYGAGGSTHVDSL
EIVTKLQKEYTLETMAHLTCIGSSTDDVASFLDALTAAGVENVLALRGDLPQDTDTNPVS
SPLLQHASDLVSLISSAHPAFGIGVAGYPETHPEALSPESDLSYLKLKLDNGADFAITQL
FFNNELYHDFVQRSRAAGIIKPIIPGILPVVSLKVIKRIITMCGATIPADFMAKLEEADR
RGGAAAVQEVGVAHARAQAQQLLEAGAPGVHIYTLNRAEVVLELVEGLLR
>A0A1Q7CPA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_2_20CM_2_66_6|TrEMBL
MIAAKPSRLRLDTASRAALLGFLERPRYEVLPTEEAQDLVARNLPTEVTVTITSSPRRGI
EATLSLAEKLAETGYSVVPHLAARLVRDAAHLQEIRSRLSAIGGRVFVVAGDSQEAAGEF
PDSVSLLEAIAAGSPAMNEIGVTGYPERHSFIDDDLTIQAMWDKRRLATYIVSNLCFDVR
VVKRWVARVRKRGVKLPVYIGMAGVADPAKLLRVSTRIGLSDSARFLRGHSNWLLRMIQP
GGYAPDRFATGLMPELARPDRRFRPTLRSPGRQSSCRCRR
>W4TKG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium acnes JCM 18909|TrEMBL
MVSTGLRTVGHLTCVAQSVADVEQMVADYAESGIGHILAIRGDMLGGVGQPWVAHPWGLP
NATELVRLVKRVHPEACIGREGA
>A0A1G1K174|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica bacterium RIFCSPHIGHO2_02_FULL_46_11|TrEMBL
MKIADCYRTKKHTFSFEFFPPKTDEGETKLFQTITQLKSLHPSFVSVTYGAMGTTRDNTI
RIVEKIKNEIGLEAAAHLTCVGHTQDDIEAVLAELHERGVENIVALRGDPPKGETEFKPV
PNGFRYGSELVRFIRKHPKYGKAFSLAVAGYPEGHIECKDKGKDLQHLKQKVDGGADVVI
TQLFFNNRDFFDFVDRCRKIGITIPIVAGIMPVTHGPQIQRFASMCGASIPKVMQEAIQE
FGENQSSVEAFGIEYATKQCRELLDSGIPGIHFYTLNKSHATERIYTNLGLAQSN
>A0A2M6VSE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. 15K|TrEMBL
MSGLKLPISLEFFPPKTPEGADKLRGVREKLYALKPEFCSVTYGAGGSTQEGTFSTVSAI
LGEGVAAASHFSCIGATKASVREELATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLV
AFIRAETGDDFHIEVAAYPEIHPQAKSPEADLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGYGDDIASIKAFGL
EVVSDLCEQLINGGVPAIHFYTMNQSAATLDIVERLN
>A0A2U2X991|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algibacter marinivivus|TrEMBL
MKVTEHIEKANGKTLFSFEIIPPKKGKNIQELYNNIDPLMEFEPPFIDVTTSREEFIYIE
KEGLFDRKITRMRPGTLGICAAIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGINNV
MALRGDAMKGEQYFKATKGGHSYATQLVNQIQNLNSGKYLHGILDVDDKADFCIGVAGYP
EKHLEAPSMKTDLKRLKEKVDAGADYVVTQMFFDNKRYFDFVEAAKKEGINVPIIPGIKP
IAVNRHLQLLPQVFKIDLPESLITEVYKCKDNKQVRQVGVEWCIQQSKELLDAGVPVLHY
YSMGKSDNIKAIASALF
>A0A3R6NBP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF35-15|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPTLSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPALCIGAACYPEGHVESVNKTVDIDHLKEKAEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A3N9V7U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
VRMGNIALAELIQREVGIEVIIHVTCRDRNLIGLQSELMGASLLGIRSILAVTGDPASMG
EQSGASSVFDLNSLGLIALLHDLNAGLNGTGNSIDRGTGFTIGAAFNPNVRNMESQVARL
EKKLANGAQFVQTQPIFDLEKLDTMLQLTSSLPIPILPGILPLVSERNTEFLHNEVPGIT
VPEEIRNRMRGKGKEEGLREGLAIAREFIDAARSRVGGFYLMPPFGNYRIAAELVRYIRT
GK
>A0A182ATC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp. NIES-981|TrEMBL
MLLQQALTRGLPAITAEVTPPRGADPARTLAAAASLRPWVHAVNVTDGSRAVMRMSSLAM
CRLLLEAGIEPVLQMACRDRNRIALQADLLGAHALGLRNLLCLTGDPVRAGDQPDARPVN
ELESVRLLQLVASLNAGQDPVKGSLPDGGTAFFAGAAADPQSPSWSGLKARMRRKQRAGA
RFVQTQMVTDAEALRRFVEEIAAPLGLPVLAGVFLLKSAKNALFINRVVPGANIPQTLID
RLAAASDPAAEGVAIAAEQVARYLEIAQGVHVMAIKAEERIPLILARAGLAPLPETAGGT
GIPARAPQLL
>A0A4R9WD15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2E.F.Ca.ET.219.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDAVIREFVDFGVTRFVALRGDPAAGVGT
VYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
AGSAAA
>A0A1F5AJX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium RBG_13_64_14|TrEMBL
MDKIFHVELQTPKRSSEDIEKDLHVFEEKYRKVMDAGWIVCITDNPMGLLSYGAMETIDL
MGLPVHPEQLMVHLNTFHTKKELDEILAAFKTAGGKHLLIVSGDGSQRLHRLEPAEVGVE
ALTVTSVELLRYIDREFPGQFTCGVAFNPYEPQDAELEKMRRKVDAGASFIITQPIIGRD
DRLAGLGPFRLPVTLDAWMSKKLHLLSECVGHEIPEGTPYDPMENLRELRRNYPDYGLYL
AILGFKTQYPLLPEIWK
>A0A8C6MU37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mus spicilegus|TrEMBL
MNHQKAKVFPAGHCYPSLGMWAPEAGCVRLSVPPSISRNPAMVNEARGSGSPNPRSEGSS
SGGESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRF
DRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCQQHPEEITG
HLHRAKQLGLKNIMALRGDPVGDHWEAEEGGFSYATDLVKHIRTEFADYFDICVAGYPRG
HPDAESFEDDLKHLKEKVSAGADFIITQLFFEASTFFSFVKACTEIGISCPILPGIFPIQ
GYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHF
YTLNREVATMEVLKQLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQD
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLS
GEPNRHGYRVTCLPWNDEPLAAETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDSCLWQVVEDTFELLNRHPTERETQAP
>A0A842UKA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon|TrEMBL
MNFKEKITSNQFVVTGEIAPQKGVDTSPVVSAMNLLRDHVDAVNVTDNQNACVRLSSLSA
CRILIDNDVEPIFQLTCRDRNRIALQSDLMGAWVLGVRNVLILSGDHPASGDHPSAKPVY
DLDSIQLLGLVNNLNNGVDLEGNLLNNPTGFFMGAAANPGADDIESEVSRLEKKKNQGAC
FLQTQVVYDVDGFKKFLKAIKPLNISVLAGIVPLKSAGMARFMNENLPGVKVPGELISEL
ETARDPVGVGVNQAARIIREIKPYCQGIHVMALGAEKQVPKLLREAGLR
>A0A7C7SZY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thioglobus sp|TrEMBL
MQLSFEFFPPRTDQGKQNLRQVRQELSVINPHYFSTTFGAGGTTQDATLETVLDIQANDG
IPAAPHLSCIDSEKSKILTLLNQYKDAGINRIVALRGDIPSGVRDIGDFHYANELVEFIR
TEFNDHFHIEVAAYPEMHPQAKNMQTDMIHFVNKIKAGADSAITQYFYNADAYFRFVDEV
QKQGIDAPITPGIMPITNHDQLMRFSTMCGAEIPRWIEKRLSGYGDDMQSLREFGFDVVA
NLCDQLKTQGVDNFHFYSMNKSQPSLQLAKLLM
>A0A7J2JKE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon|TrEMBL
MSKLSKNFGKEFIVTGEVAPPRGPDLKEFMHEVEEFKKLMNRLYGVNVVDIPGARLLMSS
LAASILLKQNGIDPIYQLVCRDRNQLALEADLIGAAAFGIENVLALTGDHPSCRSSDHPK
AKGVFDLDSATLIKTMKLMNQGKDLVGVDLNKPTNFFIGAALAPGATPIEGEIHKTKRKL
DAGTDFFQTQAVFESSMMWDFLDKYESLMKEDIADKILMGLVPLYSYGMVQFLRTMPGIV
ISEETGKRIKEADDPVEEGINIASELIDMAREMNLAGVHIMPSGKIEALMRLLESI
>A0A2N6G0D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp|TrEMBL
MLTDKIRNKQSGILLYGITPPKIKHTEDEIRDIAARHIERISKLPIDGLVLYDIQDESDR
TDEKRPFPFIKTLDPCEYSRTYLKDLEIPRVVYRAVGNYTEKTFPAWLEITKENQVHSVF
VGAASHNIKKPMTLPEAYRLKKEINNNLCLGGIAIPERHMVKHDEHIRVFSKIDNSCEYF
ITQCVYNLEASKIFLTDYAKYAKENEKEIVPIIFTLTPCGSAKTLDFMKWLGISIPNYLE
EDLKASGDILHDSMKLCIDIFKELYTFGKEKGIPIGCNVESVAIRKEEIEASIELLHEIK
KIMEEN
>A0A6M2ETL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Populus davidiana|TrEMBL
MKVIDKIRAAAAAGDSNANGNGGDSCSNNKVVFSFEFFPPKTDDGVDNLFERMDRMVSHN
PSFCDITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQ
NVLALRGDPPHGQDKFVQIQGGLACALDLVKHIRSKYGDYFGITVAGYPEAHPDVIGSDG
FATPEDYHKDLAYLKQKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPIN
NYKGFIRMTGFCKTKVPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLY
TLNMEKSALAILMNLGLIEESKITRPLPWRPPTNVFRVKEDVRPIFWANRPKSYLTRTIG
WDQYPHGRWGDSRNPSYGALSDYQFMRPRARGKKLLEEWAAPLKSVEDIYEKFKVYCLGK
LKSSPWSELDGLQPETKIINEQLGKINLKGFLTINSQPAVNGEKSDSPSVGWGRPGGYVY
QKAYLEFFCSKDKLNALVDKCKSFPFVTYIAVNKGGSWISNVALTDVNAVTWGVFPAKEI
IQPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEVKSSYFLVSLVDNDYIHG
DIFAVFADL
>A0A5J4LQV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces angustmyceticus|TrEMBL
MRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTADLRHIIGQYADAGIRNMLALRGDPPGDPMGEWVKHP
DGIGYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVDKCRAGADFAITQMFF
YPEDYFRLRDRVSAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQQS
>A0A1C3VW68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium miluonense|TrEMBL
MSSNSENAQDGIRISFEFFPPKSEEAEQQLWNTVADLSDWEPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLAAGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVAALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRAAGIKIPIVPGIMPIQNLTQLKRFAGACGTNIPSWLDERFEGTDD
YAEERARVAAEVAAEQIQDLVRRGIYEFHLYTMNRSPLVSAVLERLGIQRKAEARAGAAA
>A0A0N8SJG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. primulae|TrEMBL
MWLHRTLRAGRWDLWERTCPRRHLIYHPSFVDKQISSRTSPLPLCDLPVRFKMRSASMSQ
ERRYSFEFFPTKTDAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLENEV
KVPAAPHLSCVGDSKADLRGLLSQYQEAGIKRIVALRGDLPSGMGMASGELRHANDLVSF
IREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFYFVE
RVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQSFGEEV
ITEMCERLLQGGAPGLHFYTLNQADPSLAVWNNLKLPR
>A0A244D8B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. AJR|TrEMBL
MKVTQHIENANGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKIGGNSFAIDLVKQINELNCGKYLHEVMDVDNKADFCIGVAGY
PEKHLESPSLTSDLKRLKEKVDAGADYVVTQMFFDNSKYFEFVKRAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLINEVDKCKNNVEIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A4P7N623|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnaporthe oryzae|TrEMBL
MDKITDKIAALPPDASYFSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
AQKSLELAEICQRELALTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRPGE
YAIPDDSEGDVNEFTWAIDLVRYIKLNHGDYFCVGVAAYPEGHAEESHPTNQSLEHDLPY
LVEKTQAGADFIITQLFFDISAYEKFEKTLREHPSGAFKDIPIIPGLMPIQNYQMIKRTT
KLSHAKIPDPLMARLDAVKKDDEQVKKVGVDIISELVDQVKEVKNRSSGPKGFHFYTLNL
EKAVSFIVERTNLIPATTPDDDEVAVVDDVALPSIHLNGATPAKDHLSVSSLHPPTHTNS
RRPSTIGSDPRNRVIVSSGRPASHPDYEATGFEASVPAQAINSRANTLAISEGEGVLGRE
ATWDDYPNGRWGDARSPAYGEIDGYGVSLHMSGTQAVQLWGRPATVEDVSNIFMRHLRGA
LPAIPWSEEEFNAETETIRDTLLALNSRGWWTVASQPAVNGLRSNDRTFGWGPQNGFVFQ
KAFVEMFLPSKDWKALREKLLSEKDVVCFYASNAKGDFESSDGGGDAPDGAPTGNGFADE
QPLPSGSSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWAEWAKVYGKDSPSEKL
LESLRADLWLVNIIHHDYIEKEALWDLLLK
>A0A270B638|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. GW247-27LB|TrEMBL
MTSTLNSIAEARRAAATPLFADLAGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASKDEIDAVARAYWDAGVRHIVA
LRGDVPGGAPYRAHPHGYANAAELVAGLKAIAPFDISVAAYPEVHPDSDCPQADLDNLKR
KLDAGATRAITQFFFSPDAFLRFRDAAAAAGIDTPIIPGILPVSNVSQTRRMADMCGAAI
PSWMVSLFEGLDDLPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPAVAPIKEQAA
>A0A177YQW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus kyotonensis|TrEMBL
MTRTPSIVDRLRTSSDSRIPFSVEFSPPRDHDAEARLWRAVREFEQMQPAFVSMTYGAGG
STRDRTVRVTGQIAEETTLLPVAHLTAVSHSIAELRSMVGAYADRGISNILVLRGDPPGD
PLGDWEKHPEGVEYAEELVCLVRELGDFHVGVASFPEGHYRAVDLEHDTRVLVNKLRAGA
EYSITQMFFDVDDYLRLRDRVVAFDPEQGAKPIIPEIMPITSLRSVRRALSLSGSALPRH
IDDRFVKAAGTGSEEDRAAVREVGIELATSIGERLIAEGAPALHFITLNFARATREVLVN
LGLSPARV
>A0A3D9GRE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. VMFN-D1|TrEMBL
MKPDLRQAWDQQVLIGDGAMGTFLYQMGFPVGISYEELNLTSPEVIKDVHRRYVEAGAQI
IETNTFSANFDKLSKYGLESKVEDINRAGVRIAREVAGSAGYVVGAIGSIRGGKRTNVST
AELKKYFEQQIQALLQEGVDGILLETFYDVEELYLALSIVRKLSPLPVICQFAVEDVART
LDGYTMPEAFRMMQQQGADVIGFNCRTGPNGIMSAMKTLGGHMSVPMSVYPNAGVADYVD
GEYQYGAKPDYFGQMAVKFADLGARIIGGCCGTTPAHIAAISSALQGYEPQPITYGPIDI
APAPIEIHEHLAPDGDGEGEGGSPNLVDLVKERHTVIVELDPPRDLDIAKFMKGAQVLKD
AGADALTLADNSLAVTRMSNMALGHLVQAETGLRPLVHIACRDRNLIGTQSHLMGFDALG
IDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFVVGAA
FNPHGKHLDKAVLRLERKIAAGADYIMTQPVYDPELIRALKEATSHLDIPIFLGIMPLAS
GRNAEYLHNEVPGIQLSDDVRRRMSGLEGEEGRAMGVAIAKELLDVAMEHFNGIYLMTPF
MLYDMSAQLISHVWEKSGRRQPPLFHR
>A0A7X8Y174|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. P38BS-XIX|TrEMBL
MSSKSESSQNGIRISFEFFPPKSEEAEQQLWNTVAELSDWEPEFVSVTYGAGGSTKAPTL
SAVRRMIHETPFTTATHLTCVGATREDTHRVIDEFLAAGARRFVALRGDPPGGVGSAYQP
HPGGYANAAELVGALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGANRALTQF
FFDNDAFARYHDHVRSAGIKIPVVPGIMPIQNLTQLKRFAGACGTSIPSRLDERFEGLDD
HPEERAKVAADVAAEQIQDLVRRGIHEFHLYTMNRAPLVSAVLERLGLQRRIDAPAGAAA
>A0A7X0EVM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluvialis|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMTVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVKVPTAPHLSCVGDSKAELRELLNTYKASGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGEHFHIEVAAYPEVHPQARSFEDDLHNFVRKAKAGADSAITQYFFSADCYFY
FVERVRKLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDLESIQAFG
EQVVSAMCERLLDGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1F2WH02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Solincola sediminis|TrEMBL
MTLLIKKHTKPGIKEIFESGTFLVSGEIGPPKGTDIDEMIEHIDLLKDKVHAMNITDNQS
SVMRYPSLGTALIIKEHGGEPNLQVTCRDRNRMAIEADLLFAYTRGIRSVLCLTGDSIPV
GDHKEAKAVFDLESVQLLQLISGMEAGKDTGGNELGGGVEFYKGAIVTPEAHPIEPQMIK
FEKKIEAGAQWFQTQAVYDMENFKRFMEAARKINDKVKICAGLVLLTSMGAIRYMNANVP
GVFVPDNLVEEMKEAPKGEALNTGIRILARQIRQCIDEKLCDGVHIMAIGKEGAVPKILE
EAGVDITKM
>A0A1W9GIQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SG-bin2|TrEMBL
MSREPRRLKDVLDQGQFAVTIEYNPPKGTNIAGILDNAKDLIGLVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNVLCLTGDYPTVGDHKE
AKPVYDLDSVQVMKLVQGLNEGRDMAGHKLDGPTAFTIAAAATPEADLVGPVLAKFEVKV
KAGAQFFQTQAVYQPDIFASFMKAVRPFKVKVLAGILLLRNAKMAEFMNANIPGMSVPQE
MIDELRAAGDKSEDAGVEIAVRAIKAVRSHCDGVHIMAIKGIHRLREIITKAELG
>A0A0R2AD95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paucilactobacillus vaccinostercus DSM 20634|TrEMBL
MLSFEIFPPREHASAKTLDRFYETLDILADLKPAYISVTYGAGGAGSQTGTLHLVKYIRE
HYGIETVPHIPAMQFTKASVQDYLTELATANIQNVLALRGDLPADGTQPRDFQYASDLVH
YIKQVGDFNVLGACYPDVHPEAADAVRDIQNLKTKVDAGVSQLVTQLFFENDHFYHFIER
CQLASIDVPIQAGIMAATSEKQIERMATMCGVTLPPKFAKMMDRYKGNKIATRDAGIAYA
VDQIVDLLAHDVDGIHLYTMDNPVVAQRICDAVKTLI
>A0A087C0S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium mongoliense DSM 21395|TrEMBL
MHRPAFSLEVFPPRRHAPIGTIYDTLDGLEDVDPDFISVTYGTGRSADRTATLRIARTIH
DEYRIPVVAHLTAQYLDRNQADETLDAFEAAGVHAVLALRGDRDPDRPPTDVFAHASDLT
AYIADTHPDMTIYGACYPECHPQSKNRKDDIGALKLKVDAGAKRLISQLFYDDDDFLSFL
EIARASGIAVPIEAGIMSVTDAAQVGRMVRLCSSRVPRSLSRILERWGDDPSALREAGII
YASQQITDLVAQGVDGIHLYTMNRPAITRRIWANTRGLFATGTNAID
>A0A2N2KAP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-15|TrEMBL
MDFQKCLSTGEFVILAQMNTPKGVNVSEMVNNARRIKGRIHAVVIPDMDNGVMRMSALAG
GAIMRQQGLEPIIHVYARDRNRMALQGDLLAAHVLGVQALVVVRGEDMSQGDHVNAKCVD
DLDEISLFGAIRCLQNGVDIAGSELNGNPSFTVGCTIRPSVDEKSLDSEIEAARKMVEAG
ARFILCPPVFDVDRFSTFAEKAKGLGAVLIPTVFLLKTVGIARYMATYEPGAFIPEHLIK
RMRQAKNREMEGFVIAGETIKHLKSLAGGVQIVTLGWEHRLSTILDYAEI
>A0A3R9W0H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC01280|TrEMBL
MSVAFVNPTYSFEFFPPKSERGEQTLWDAIRRVEALSPDFVSVTYGAGGSSRDRTIEVTK
RIATETTLRPVAHLTAVGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRGAWTPHPQG
FTYAYELVELVRSLGDFRIGVAAFPEGHPRSPDPASDLAHFVAKCRAGADYAITQMFFDP
EDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAKDDPAA
AYRIGVEHATQMGLRLLDEGAPGLHYITLNKSTAALEIHRTIMSARSVVHV
>A0A5S3P3H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania marisflavi|TrEMBL
MEQPLFSGLPGDIEVSFEFFPPKNDKMAETLWQSIETLAPLGPRFVSVTYGAGGTTRERT
HQQVVRINQETGIPAAAHLTCVEATRDEVDAIARHYWESGVRHIVALRGDAPDGKSAYTP
HPGGYENAADLIAGLNAIAPFEISVAAYPETHPDSPDAQADLDNLKRKFDAGATRAITQF
FFDPECFFRFRDQAAAAGIHGEIVPGIMPVMSFASVQRMSGLCGTAIPDWMEGLFDGLDE
RPAARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKDN
>A0A3R8U3X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. 278|TrEMBL
MTAISFEFYPPKTDDQRAQLDRTASRLKGYGPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFDAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYAAELIAFI
RAEHGDFFHIEVGAYPETHPQSDDALRDLRYFKDKIDAGADAAITQYFFNADAYFHFVDA
VRRLGVQVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDADAVREFGAEVV
AQLCQRLVDGGAPGLHFYTLNLARPTTQVLKLLGR
>A0A495X8C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix variisporea|TrEMBL
MTSVVERITTGRPVFSVEFFPPRDNDDERVLWKAIRELEALDPAFVSITYGAGGSTRDRT
VRTTARVVQETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILAVRGDPPGDVNGEWV
PHPQGLTYAEELVRLCRELGNFCVGVSAFPYGHPRSADLDTDTKYLVQKLRAGADFAIAQ
LFLNPEDFLRLRDRVAATGCDTLLVPGLMPLTTPRTLAKSVELSGAPLPASVAARLEHLA
DDPVAFRKAGVDLVTEMGERLLAEGVPALHFYTFNRSKATREVVGRLGLVPART
>A0A4R3AS59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. JUb78|TrEMBL
MKIVDHISNAKGKTLFSFELLPPAKGQGIQSIFKTMDALMEFKPPFIDVTYHREDYMYKK
HESGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDPDFIPTEGGHAFATDLLQQVADMNQGQYLHEDIAISEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVNKCRENDIHIPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSEAVSGCKNNADVRQVGEEWLVQQCKELIDFGAPVLH
FYTMSNPGPTKSIVEKLF
>A0A4R3X0K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neorhizobium sp. S3-V5DH|TrEMBL
MTANREPFSVSFEFFPPKSDEMEAQLWEAVEQLAGWAPEFVSMTYGAGGSTKEPTLAAVT
RMIGEARLPTAAHLTCVDASREETRSVIEAYRAAGVRRIVALRGDPATGIGTAYLPHPEG
YAQTADLVRALMEYGDFDVSVSAYPEKHPESADLAADIEALKAKADAGASRALSQFFFDN
DIFERYLEKVQGAGVSIPVVPGIMPIQNLTQLKRFARRCGASVPAFLDARFEGLDEKPED
RAKVAADVAAEQMEDLSRRGIHEFHIYTMNRAPLVSAVLERLGRRQIASPRTVAA
>F0JCD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio mercurii|TrEMBL
MKIIDRIRDNGPFLSLEFFPPKERDQWPRFFGQVERLAGLDPLFASVTYGAGGSFQDNTL
EIAAEVHKRFGLTTMSHLTCVGAEKRSIAAYMDRLLEAGVSDVLALRGDMPGNDPAEVWK
DFRHASDLVEFVRQGWPEAGVAAACYPDAHPESGSIDDDLRWTCHKFNTGADFGVTQLFF
DVRRYQDLVRRLRSRGIDNPVVPGILPVLAMQSLDRILSLCGANIPLKLYLEIREAFDTG
GDEAVRRKGVDIARRQIRELLALGAPGIHLYSLNNADVCLDILRDVPELRG
>E4LH20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp. oral taxon 137 str. F0430|TrEMBL
MAQGRAELRDYLKTAPLIFDGGMGTYYAQKLHTRGKGVELANIETPIVVSDIHTEYLRAG
AQAIKTNTFAANRIVYQGDEELVRRIVTAGWEIAARAAAPFDAYVFADIGPVMGLPHADI
IDEYRFLADIFLALGARHFIFETNSSDEGLIETAAHIKQKCPEAFVLNSFSAYPGGYTRD
GRFVEDLVRAVAGSGYVDAVGFNCVNGTKQMKELIRHLGKQILPLSLMPNAGHPVVVDGR
TFYESAPDYFGSSLAAIRREGVSILGGCCGTTPAHIKALCDALAAQGDIMPEEDEETPPQ
VALLPKSPFYEALKSGAKPIAVELDPPETGSADKFMAGARELMAAGINAITIADNPIARA
RMDAAMLAGRVHRELGIEPIPHMTCRDRNLNAIKSLLLGLSAEGVHNIITITGDPIPTAE
RDEVKSVYQFNSRKLASFITSLGSRGDVVPFHIFGALNVNAKFFGTQINLAKKKVEEGMM
GFFTQPVLSERAKENMRAVRETFPEALILGGIMPVVSERNARYMESEITGIHVEERIIDM
YRGLDRTQAEELAVRLSLEIARDIEPYIDGYYIITPFSRTALVARIVKALKK
>W0JU34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halostagnicola larsenii XH-48|TrEMBL
MRYELMPFDSFGEQIEHLPDGATVTITASPTLELEATIDWAERAAERGFEVVPHVSARYV
RDTDHLREIAERLRDAGITDIFVPGGDREEPIGEFDSAYSLLVALEELEYEFEDVGITGY
PEGHDFLSEETLAESMKKKAPFATYITTQLCYDPQAIIDWIDTIRSRGIELPVEVGIPGV
MKYQKLLNISKKVGVGDSVRFLKKTTGILGFVRQFIGSRGKYEPDQLVDGLKPYAADPDY
GIRGLHIYTFNQVPDTESWRKGRL
>A0A2P7YUH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] pseudohaemulonii|TrEMBL
MKISKKLDDAHSCSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYELNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALSKAHASGCQNILALRGDPPLD
GSESTGDFKYAKDLIRYIRKNYGDHFNIGIAAYPEGHPEEEDDGKLLSYLKEKVDAGADF
IITQMFYDVDNFISWCLKIRKIGVDIPIIPGIMPISTYSAFIRRAKWSQVKIPEHFLQAL
DPIKEDDYAVREKGTQLVGEMCQKLIDSGYVNHLHFYTMNLERSTIMVLEHLNLIEHVKD
NAVVGDELPWRKSLHPMRSKESIRPIFWQNRKYSYISRTSGWDEFPNGRWGDSRSPAFGD
IDLSATELLRQSPKRAFELWGCPQTLADLSQILISYLQGEIKSLPWSDGPIGDDTEVLKP
ALIEMNKKGIFTLNSQPALSAIRSNDEVFGWGPKNGFVYQKQYLEFFIHKDALNILLQRV
EEHNARDAHSVVTYYAVDKQGTLSTNAHDDDINAVTWGVFPGEEILQPTIVEKVSFLAWK
DEVYRLLDEWVKIFHTKSVKEEVEEAKIDAFSKLLTGFGDNFVLCNFVNNDFTSGNNIIF
DLFQDLPVASL
>A0A1V4RNG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4484_190.1|TrEMBL
MSEYKAGSNLEKVLKAGHFAFTGECGPPQGANIELLKEKAGHLKGCVDAVNVTDNQTAVV
RMSSWAASLVLLQEGLEPNFQMVCRDRNRLAIQSDILGVYTHGIRNMLCLSGDHQKFGDH
PESKNVFDIDSMQLINTVKTMRDDGKFLNGKNIDVPPRLFIGAASNPFAEPFDFRVYRLA
KKIEAGADFVQTQCIYNMDRFREFMKRAVDMGLHEKCYLLAGVTPMKSVGMARYMAKQVP
GMEVPESLIKRLKGAGKGKVAEEGIKFAIEQIHEFEEMEGVAGVHLMAIEWEHRVPEIAE
RAGVLPRPQV
>A0A0J6SNJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium tarhaniae|TrEMBL
MYPTAFRPSRESRRPIRVSFEFFPPKTPEMEATLWSSIERLAPLGPSFVSVTYGAGGSTR
ERTHNTVARLVSETELKPAAHLTCVAATKGEVDDVVRAYHEAGVRHIVALRGDPAEGVGT
AYTAHPGGYERSCDLVAGIKRIGDFEVSVSAYPERHPEAGSLDQDLDALKAKVDCGADRA
ITQFFFDNDLFFRYLDRVQARGIDIPIIPGILPVQNFKQAANFARRTGASVPDWLAARFE
GLDDDVATRKLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRAAPVVVE
KAAA
>A0A1Y4GHF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonibacter sp. An230|TrEMBL
MTTIRSIYRTARACGRRPVSFEIFPPKGDLTLETAHDVAGELAELAPDFISVTYSAGGSG
NKRATADVAQMIQRDFDVPAVAHLTCVGATEETIARAVDDLRAHGIDNVLALRGDAAGAD
EPGTYRYARDLISRLAEEGFCVGAAAYPEGHIACDDARANIEHLKQKQDAGASFFVTQLF
FDNEFFYRFWEAARNAGVTAPIACGIMPFLGKAQIQRMVFMCGASLPSPVVKLLARFEDR
PDDLRRAGVEYACAQLVDLDAHGVDGLHVYTMNQPDIARASMAALRAAWRA
>A0A1L9T3B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus sydowii CBS 593.65|TrEMBL
MEKITDKIAALPPNANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRQKYGDYFCVGVAGYPEGHPADSFQDVQDPKVDLPWL
VEKTQAGADFIMTQLTYDIDAYTNFENLLRNHESGAFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPPILEKLEEVKHDDDAVKRLGVDILAELVEGMRKLPTPRSRGFHFYTLNLEKT
VSFILERCKLIPDHTDDDAAAVSEEDSLLTADAARAASSARRRRASSLSSLPHNRVIVDK
ISEPSSKESVTHEATAASAGMPAQPPDRNTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVAPSVAHRIWGYPVSPEDISKLFRRHVSGDLHMVPWSEGGAEENTS
GLNAETETIRPELLALIDKKGWWTLASQPAVNGVRSDNPIFGWGPPGEGFVFQKPFVEFF
CPTSDFTDTLKPLLQKHGHEKLAWFAANANGDFESSLPAQTSDTEPIEMNPNNVNAVTWG
VFRGKEIITPTIIEEVSFRAWGDEAYRIWDEWRRIYPRNSPTERFLEKTKNDVWLVCVVG
QDFGAGTEIGSKEEDDERKWMWKTLANS
>A0A4Q9GSW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hansschlegelia quercus|TrEMBL
MPNDRLSRTSRRPIRVSFEFFPPKTPEMEETLWRSIERLSPLQPTFMSVTYGAGGSTRER
THSTVARMVKETDIQPAAHLTCVSATREEVDAVVDSYREAGVRHIVALRGDPAGGVGAAF
EPHPGGYASTADLVAGIRRRAPEIEMSVSAYPEKHPESPSVDADFDVLKAKVDAGATRAI
TQFFFDNNHYLRYVDEARKRGIHIPIIPGIVAVSNFKQTANFATKAGASVPDWFAARFEG
LENDPSTRQLVAAAVAAEQVLDLVDHGVKDFHFYTMNKADLVYAVCHLLGVRPEVGAAAK
AAAA
>A0A209BGZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CS113|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPGADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PPELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A4R9BEH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Sr8|TrEMBL
MTETTTTRTRGRRIPFSFELYPPKSEAASTALTHTIDRLAAAGPDFISVTYGANGSSRTS
SLDVLRYILDATGVDPMAHLTCVGSSAAEASRLIREFLDAGVRSFLALRGDPPQGVDEGE
TFLGDLGSAAELVQLIHRVQAERVPYRETVIPGLPGARAVKTEREKVRIAVAAFPNGHPR
SRSTSQDIDTLLAKQAAGANLAITQLFFHADHYLSFIHRAREAGVEFPILPGIMPVTSPN
RLRRILELSGEEEPADLSIQLQVEPTEQGQREIGITHAVGLARELIAGGAPGLHLYAFNQ
HETVLAVLEGCGALPASSPHAATQITAAQRTAHRPTSTAHTHPVKESA
>A0A1N7S5C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia ribeironis|TrEMBL
MNPIELSFEFFPPKTQEAVDKLRATRAQLALLKPKFVSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHLSCIGSSKESLRAILNQYRAHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCKRLIDAKVPGLHFYTLNGAAATKAICERLGV
>A0A0M7LY65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp|TrEMBL
MSSLKQALGERRFACVLEIIPQHAPARQAALQRIVRRGRLAGWPLLPAFADRVGLHSDLS
PLQGAGALGDPASSLLHFSGKDRARADLLRQMDAMQARGLSQLLLLSGDRLPGHDPGRAP
VRYLESVPALQIARERGPDWLLGAALNPFKYREEEGAAQYLKAQKKLLAGADFLTLQLGF
DAAKHLEAQAWMRAQGRVKPMLACVMQLTHRRAAALQDVPGIVITDAMRELLGREQQISP
AHASARSLERLALQIVGLQWMGYAGVHLSGVHTLDELLLLEQAIAEQRDAVTSLSDWAQR
WQASWRMPGMPQAGFAPDIDTWELGQSDVAATPGERLRYALLSTVHEQLFNRTGWLGSAF
GWSVTRPFWKTGVAAQALHAVERTLKRPLVGCDTCGTCRLQDTLYVCPETCPKGLANGPC
GGTRLNRCEFGDRECVHSVKYRIAKSADQLPALAQTLIPGIEAGDRHRSSWPEWFKPEDP
TPGNDCQSLPKSG
>A0A7X3UQZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MNTSLLDHLRSSMLVADGASGTMLYARGVPMEVCFDEINLSRPDLIRKIHEEYVDAGAGL
IETNTFGANALSLSKYNLEDQAETLNARGVEIAREAAGSRAFVAGAVGPAQGLPHWDYTK
ADHRRVHAEQIAALAGGGADAIILETFLRLDELKAALAVCQEICDLPTICQLAVDQYGQS
DDGFEVVEAFDQLRAAGADVVGVNCRSGPKGLLDALAPVPLSEGLVLSAFPNAGSPVYVD
GRFIYEATPEYFATSALRLRDQGVRLIGGCCGTLPEHVQAMARALEGREIVTRKKVLPVE
VRVPARPERIARPVPAPPAVEPSIVDLVKERVTVIVELDPPRDLDHGPIVRGALALKKAG
ADALTMADNSLAVTRISNMAVGQIVKEEAGIRPLLHITCRDRNLASLQSQVLGLHALGID
HVLAVTGDPVKFGDQPGASNVYDVSSFELIRLIKQMNDGVGFSGRTLNGRTAFTVAAAFD
PNGPNLDRRIRRLERKVEAGADMIMTQPLFDRRQAKQLYEATRDAGVPIFPGVMPLVSDG
NTEFLHNEVPGFVVPDDVRARMARVGRGRKARREGVAIARELIESVLANFNGLYLITPFN
RYPMTVELTEFALQATTRNSPE
>A0A2V7TFM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYGKGFFLNVCYDELNLKQPRLVQEVHAEYVRAGAEILETNTFGANPLKLNSYGLA
DETEKINRTAAELARAAGGGRVSVVGAIGPLGIRIEPFGPTSQAEAEAVFARQVQGLLAG
GVDGFILETFSDLDEMHAALRAVRAASDLPVVCQMTIGTDGLTYYGTDPDTYTKQLAAWG
ADVIGVNCSVGPAGVLEAVEKMVKATDKPISAQPNAGLPKDVGDRKIYLASPEYMASYAR
RMIETGARFVGGCCGSTPEHIKKIRDYVASVVPRQPSVVVSRAQVHAPAGVTPIPLAEKS
RWGAKLARGALVTSVEIVPPKGVDPKPMLEQCRALKAAGVDAVNVPDGPRAQSRMGVLPS
ALLIEREVGIETVIHYCCRDRNLLGMLSDIIGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLTNLVYRLNQGLDPGNNPLGGMTKWAIGVGVNPGATDKDRELSRFAWKVDAGA
EFAVTQPVFDARQLEAFLKQVEQFQTPIVAGIWPLISLRNAEFLANEVPGVSVPDEVLQR
MRKAQEKGKEAALAEGVAIAREMFTRVKQMVQGVQVSAPFGRVEVALQVFQ
>A0A800KIM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTQSIETPSNLRSLINDGNIHVLDGAMGTEIYARGVFVNLSYDGLNLENPDLVQAIHRDY
VNAGAEIIETNTFGANPIKLSGHGLSEKTELINKTAAQIARKAAGDKVDVLGAIGPLGVR
IEPFGPTAREEAQDLFTRQILGLLEGKVNGFILETFSDLNELEQAFHAIRTQSDLPIFCQ
VTVGEDGRTVYGTSPEAVATEVSSWGADVVGVNCSVGPAVMLDVIERMARVTTCPLSAQP
NAGLPRIIADRKMYLTSPTYIGQYARQMIDAGARFLGGCCGTGPEHIYKIRESVRRISTP
VEIPQRMARVVATETDFADETPLEKMSALGEKISKGIFITSMEITPPKGSDPTEMINQCK
LVKEAGADSINILDSPYAPGRMSSLPAAIVVENEVGIETVVHYPCRDRNMSRMISDLLGA
AASGIHNLLLVTGRPPPTGPFQPALSGIDIDSIGLTNVIHGLNQGMDPGGNSLESRTNFV
IGARMNHVATDQDKEISRLKWKVDAGAHFLVTHPVFSVETLHSFLPNISDLSIPIIGTLW
PLRSFREADYLHNEVPGIQIPESIFTRMAAAEKQGESEARSEGVKIALESFEEMHPIVQG
LQIKASGGSFSEALTLLHEVGKSQ
>A0A829BVM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira noguchii str. Bonito|TrEMBL
MKKVSEIYGSTKGPVYSFEFFPPKTPEGDLKLMETVKELSLLDPDFVTVTYGAGGSTRDK
TAQILSQISKNYSVPTVSHFTCVGANKGQILETLKGIRSSGIVNLMALRGDPPKGEGEFK
KVENGFGNATELISFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVKNLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A7C7P4R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MRSLIEDGHIHVFDGAMGSVLYTRGVFVNICFDELSLRKPEIVRRIHEEYVAAGAEILET
NTFGANPVKLSSHSLGDRTEEINEAAAHLARDAAAGQAAVVGAIGPLGIRIEPWGPTERA
EATVFFERQVTGLLAGGVDGFILETFSDLSEIDCAFAAVRKLSNLPVIAQMTVGHGSKTA
YGHKASQIAEELTKIGVDVIGLNCSVGPAVMLDAIEDMADATSLPLSAQPNAGLPRTVRD
RKIYMATPKYMALYARRMIDAGVRFVGGCCGTTPDHIKHIRDTVRLVQPRTVTVRVPDVP
QDRLEILDPVPLEACSAWGRKLSQGEPVVSVEVLPPRGWDRNAIVDPARRLKVAGVDTLA
IVDGPHSRSRMGALSAAVIVEQEVEIEAMVHYTCRGRNMLGMISDLLGAAAAGIRNLLVV
SGDPSVQGPYPDMTEVFDIDSIGLTNVIRGLNRGVDPAGNSIGEPTKFVQGVVANPGALD
LEREVTRFRYKVEAGASFVVTQPIFDPETLESFLEQVHAWKIPVLAGIWPFLNLRNAEFL
ANEVPGVTVPEEIVDRMRKAQASGDEEAMDQGVRIAVEMIKAVRPLVQGFHLSAPSRRVD
VALRVLHEAGISPNA
>A0A8D0WFG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MDRPKAKGLPAGQCCPSLGVRALEAGISRSSVPPAISRSSAMVNEPRGNGGPGPRCEGSS
SGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEVTG
YLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVSVAGYPKG
HPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACSEMGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKVGASLGHRVRGRHIYA
TIRQSRSAPPIQALCQTDTQTEPGPCPLRAPSLAREAIRG
>A0A5R9GEV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus antri|TrEMBL
MFRNERRGDGGKPDLRDILIKQAIVGDGAMGTYLYQLGVPIGVCAEELNDTRPEVIRDVH
RQYYEAGARLIETNTFAANRYKLARHGLEGDVEALNRAGVALARGAVGADAYVAGSVGSA
RPAHRVPVTDEEAEAAYAEQMSALLTEGVDALLLETFSDANDAEMAVLVARRLTDKPVIC
QLAIEAGGSAPDGRSLDDAFARLQGAGADVVGLNCHSGPYGIIRALERLTRRGDVPLSIF
PNAGLPAYVDGTFSYPAGPDYFGESALTLARLGARIVGGCCGTTPAHIAAVAKALATFSP
SDETSAEAAPPARETVSVREPAEPPEPPRREPTILDMVKERHTVIVELDPPRDLNIDKFM
KGAEALHSAGADAITMADNSLAMTRMSNSALAFLIKERLGARPLVHIACRDRNLIGTQSH
LMGLHATGIDHVLAITGDPARFGDLPGASSVYDVTSFQIIKMIKQMNDGLAFSGKPMKEK
ANFLVGTALNPNVKHLHKAVERLEKKIEAGADYAMTQPVYDPELIVKLHEATKHLDFPIF
LGIMPFTSGRNAEYLHNEVPGITLSDDVRRRMAGLEGEAGRQASLGISKELLDVAMERFQ
GIYLITPFMAYEMTVELTKYVRERAESRFPLVPTREMK
>A0A7C6DX21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MRKFRELLESDAVFVFDGAVGTRLYDKGVYINRSYDELNLSAPDLVREVHDEYVKAGADI
IETNSFGATRHKLRQYGLEEKLRDINIAAARLAREAAGDEVLVAGAIGPLGIRIEPFGPT
SFDEAKDLFKEQAEALLEGGVDLFILETFSELPVIEQALRAVRELGDFPVIAQMTIQMDG
NTTFGTSPEVFTARLDELGADVIGLNCGMGPNHILTALEMMRSVTSRPLSAQPNAGLPRD
VQGRQFYMGSPEYMAKFAKRFVQAGARFVGGCCGTTPAHIKLISDSVRSISPRRQKTADR
HEVIRLSEIKPPDVSVIDPVDRSRWSRKIALGEFVTSVEVLPPKGCDAAQTLDSIRLLKE
AGVDAVNIPDGPRAQTRMSAQATAVLVEKEVGIEAVLHYCCRDRNLLGMMSDLLGAAALG
IRNLLLITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDIGNNPIGKPTAFSIGVG
VNPGAINLEEEIRRFEWKVEAGAEYAITQPVFDTDQLRSFLKRIEHVRIPIIAGIWPLVS
YRNTEFLHNEVPGVNVTPEIMERMRIASEKGKEFAREEGIAIARESLQEVRDLIAGVQVS
APFGNVRYALQVFEVLGE
>A0A1H5SBX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomonospora echinospora|TrEMBL
MGMRPVQPDRAPSIRELLAAGGKSFSFEFLPPKTETGERNLWRTIRQLEALRPTFVSVTY
GAGGGTRDKTVDIVERIATDTTLTPVAHFTAVNHSTAELRNLIGRFASVGVRNILALRGD
PPGDPMGEWVKHPDGVEYAAELVRMIRSYGDFCVGVAAFPYKHPRSPDIDSDTRHFVAKC
RAGADYAITQMFFRAEDYFRLRDRVAAHGCDVPIIPGIMPVTQLSTIERSEQLSGAPFPP
ELAARFEAVGDDPEAVRRLGVEHAAELCQELLDQGAPGIHFITFNKSTATREVYGLLDTG
AHRAAPVSSSLTA
>A0A6F8ZF85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium R50|TrEMBL
MLPASRHSGALGRGLIAGGRTGWRTAARGRQMPATGPVASGNCDGLIPGLFLTIQPRPRL
LAARPPRAPPAQGAGLCPPFRRPHPGRAAGALATHGPEPPAGRVRPSRALRQAGSSRRMT
A
>A0A3M1F0J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineae bacterium|TrEMBL
MATGEFVASVEMHPPRGASAARVLAAARTLKEAGATVVNVADSPVARMRMSPWAVCHLIQ
SEVGLETVLNFPTRGRNLLRIQGDLLAAHALNIRNLFVVMGDPTTIGDYPEAFNHHDVVS
SGLIHLVKRGFNTGVDYAGKPIAGPTNFLVGCALNVNADRPAREVRLLKKKIDNGADFAM
TQPIYTLDALEQFIARYEAEYGPPGIPILVSILPLYSIRHARFLHNEVPGITVPQAMQDR
LERAGEEAWREGLAMARDLLAAVKEKAAGVYIMPPFRRYDLAAELLESLGGD
>A0A1G8IVQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio sp. 49|TrEMBL
MTCVGSTEEDILAVTKDLEAVGVNHVLALRGDKPRDMSDEQFEQRIFPHATDLIHFINQN
TNLIVSASCYPEKHPEAISMDSDIAFMKMKQDMGAEMFISQLFFDNSDFYRFIERARRAE
ITVPIVAGIMPITSAKQIGSTVTLAGSSVPKKLADICAKYGESPEDMRKAGIAYAIDQIN
DLKRCGMGHIHIYCMNKPKMTKEICEGIC
>A0A2S6ZPJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. guizotiae|TrEMBL
MDPDTPSLASPITEAYSLEISAKHIAGLAAAAPRITHGATIAIPYLPNQDDDARLAAARV
VRTLGFQPMPHLSARRIASREQLHAFVSRAVEEAGIERCLVIAGDPPAPLGPFADSLSLL
DTGIFERSGIRTIAVAGHPEGHPSMPATDRWEVLQRKCRSIAERGMAPLIVTQFAFDADI
VLTWLQALRAHGIAHPVRVGVPGPAGVAVLARYAASCGVGACASMLSKYGISLGKLLGTA
GPDRFVDRLASGLTDAHGEVHMHFYPFGGIAQTVAWVEQYRSRSARVQAD
>A0A380MIL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Suttonella indologenes|TrEMBL
MSLNHVQRRIPVPISCEFFPTATEQGGENLAKVRRALAVFDCEYFSVTYGAGGSTQERTL
KLVRRICEEDERPVMPHLTCISATYAELEALLDTYQSIGIKRLLALRGDVPPGSFYMGEL
DSAADLVQLVRKKWGDTAHIVVAAYPEKHPRAKTPHDDLEALKIKSEAGANEAVTQYFFN
ADAFLRFRDEACAMGIEIPLVPGIMPITNYRQLARFSDACGAELPRWIRKRLEAYEHDVE
ALQLFGTEVVASLCERLVKEGAPALHFYSMNRSQAILAIGRALSWID
>A0A428XZZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. WAC 01376|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTLRTLRTSIKLSGAPTAPRRLLDRLEPL
ADDPKAFRAEGIDAVTELCERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A7V3VDL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKIKSILESTTDTKPHFSFEFFPPKDEKIFNEFLEGFEFFSNLSPMFVSVTYGAGGSTKE
KTFEAVKHINSNFDITVMPHLSSLTHTEEEIYEILSSYTKIGIENILALRGDVPKNLEGK
FDISKATFKNALEFTKFITRKFPNKFCIGTTVYLEGFPGFNNLDKEIDYLKAKFDSGADF
GISQMFFDNSYYYKFIDKCIKKGIDKIIIPGIMPITNFSQTMNFAKKVGATIPEKIVNKF
ENSANNDNDEKTGIEVAYNQIRELNENGIKFFHIYTLNRRSITKSLIEML
>A0A7V1ZDN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MNCNKLEIIFTVIPPPLEWDISKIERKAFEVANITKILDIDFISLPEVIEERSRGQRIIP
YKMKFDNVEFGKMIKNFDNSVEIIVNKISVIMEKEEFETWIKENSKSFNYLLIVGGESSK
IKYPGYHPIPATLIAKNYFKNVYGITIFHRKDEPKKLLEKTKAGMKAFISQIVFELENAK
KVIYEYFKLCEEENIKTSKIYISFAPVSQRKDLEFLKWLGVYVPKEIENYLLEDEKKLEK
RSIEIIESLFQELCFLNIENIGINVEHVMYNNLQVAAYAVHRIKETWKWRN
>Q1AXR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129 / PRD-1)|TrEMBL
MGTSFRDLLDGRVLVGDGAMGTLLADRGVGYGHPYARANLTHPELVERLHGEYVRAGARA
IETNTFSANRIKLAGHRLEERVREINEAGARLARRAAAEAAERVLVLGAIGPLGRPLAPV
GRVPREEARALFREQAEALLEGGSDALLLETFTDLEELRLAWEAVRDLGAPVLAYKTFVE
DGETLAEGLPERAAREISGWGVELVGSNCTVGPQRMLGIVEQMSAAAGPVAAFPNPGLPQ
LVEGTVRYSHDVEHFARYGLRLAEAGARFVGGCCGTTPEHIRALSEALREFRPRRVTVAL
RGAAGPRKEGAREGGAGPRSRLAGKLHGGGFAVAVEVDLPRGNDLSGVVEAARRLKERGA
DAIDISDGARARLRMHPVAAARIVQERAGIEAVAHMSCRDRNILGLQADLLAAAALGVRN
ILAVTGDPAQIGDYPEATGVFDTDAVGLVHILSRMNRGEDLAGNAIGRPPGFLIGAAFNP
TAEDLDAEVERLRRKLEAGAHAFWTQPVFELPALERALERLEGTGARLLLGLMPLRSARQ
AEFLHHEVPGVKIPAEVRRKLAELSPQDAPRYGVEVAGNLLARARPLVSGAYIMPPASAP
ELAAEVMEALR
>A0A6B9Y790|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|haloarchaeon 3A1-DGR|TrEMBL
MSLETSTTDDGAATLLADPRFELMPFDSFGEQMAHLPDGAAIAVTTSPTLGIDATVEWTE
TASEAGYEVIPHVAARYVRDREHLDSIAGRLREAGVTDVFVPGGDREEPAGEFESAHDLL
VALEELEYEFEEVGITGYPEGHDFLSEATLAEAMDRKAPYASYLVTQLCYDPETILEWIG
TIRDRGVDLPVEVGIPGVMNYQRLLGISKKVGVGDSVRFLRKTSGVLGFIKELVGSRGQY
TPDELIDGLAPHAADPHYDIRGVHIYTFNQVPDTESWRLGRLES
>A0A7Z0MIJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MTTQQAISLEFFPPRDIAAQERLVRSAKQLLALHPAYVSVTFGAGGSTRSGTAETVKLMQ
NLGCDAAPHLSCIGASRATLGEILDAYRAQGIKRIVALRGDMPSGMGGDAGELHYASELV
AFIRQHSGDAFHIEVAAYPEMHPQASSAQADLDHFVAKVQAGADSAITQYFFNADAYFDF
VERVQARGINVPVVPGIMPITNYAQLSRFSNMCGAEIPRWIRLRLADFGDDKASIKAFGI
DVIGKLSQDLLDKGAPGLHFYTLNNADVTMAIWRQLNLDG
>Q2LQ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophus aciditrophicus (strain SB)|TrEMBL
MSALQNVLSRMTGTPLIFDGAMGTMIYEKGVFIQTCYDELCLTEPGLILGIHEQYAQAGA
QVLETNSFGANRIKLRAYGLAEKVADINRAAARLARQAAGTTLYVAGSVGPCTQGGQVIT
GRDMAEVEAAFREQMEALTEEGVDLLLLETFSDLKELQLAARVARERGVPVLASFAVDDD
GETAAGTPAEKMAAALEKDPHVDVIGLNCGTGPAGIYEALLKVLPVAGKPVIVMPNAGMP
REIGGRTLYLANPEYFTEYAKKFIELGVRGIGGCCGVHPAHIATAARAVRGLSGVRKHVE
VTTRQQAPAQKPAIPTAAKSRLAAKICSGQKVTSVEILPPRAGDFSNMLAKVRRCHEAGV
DAINIPDGPRASARVSPMITALVILREVGIEPVVHYCCRDRNLIGMQSDLLGGYAVGLVN
YLIITGDPPKLGNCPEATGVFDVDSIGLTSVVHNLNSGWDIGGSPVDPPTGIFIGVGANP
CAVDLEREIDRYFQKIEAGAEFAITQPVFDEKALFRFLDRVEKHSKRVPVLAGVWPLLSY
RNAEFMNNEVPGVMVPREILERMARCETREESQRTGIEIARAICEKIHERVAGFQVCAPL
NNVEIALSVLRKGEGREI
>A0A3N5E8P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
KLAPQGLEGRVYDINLKGAQIARAAAKDNTLVAGSVGPLGVQIEPLGKLSFDEAKDAFRE
QIKGLIDGGVDLIIFETFSLVPEIVQAVRAVKELNRDIPIIAQVTISDEGKLLSGATLET
FVAEATQLGVDVVGMNCSVGPKSMLEALENLKLLTTLPISVQPNAGLPQNVGGRNIYMAS
PEYMAEYAKRFIQTGAVIVGGCCGTNPEHIRAIRRAVHALQPAKRMDRVEADLKVTAPET
VKVYERTEKSRLANKLLRQEFVTLVELVSPRGVSPAKEVAKARRLHHFGIDAINIPDGPR
ASARMSALALASIIQREVGIETVLHFACRDRNVIGMQSDLLGSWALGLRNILAITGDPPK
LGSYPDATAVFDVDAIGLTNLVNRLNHGLDLAGNPIGDPTGFSIGVGVNPGAINFDEELR
RLDWKIQAGAEYMITQPVFDLKIVERFMKRIEHVKIPLICGIWPLISYRNAEFMNNEVPG
ASVPPEILARMRKTTTKEEGFAEGVAIARETYECIRSEVAGVQLSAPMGRIEGVFTMLGK
>A0A8J8J9U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermococcus sp. 21S7|TrEMBL
MMGLRVYTCPRKLLNGPCGGVLDGACEVNGKPCPWTGVIERLSSLEPWMLFDEHPLLAEL
ERLVESDSKPVDSFLWKNIERSKAFTVEFPVRTIRSERDILRIMSAVDADLFTVPDNPLG
YPHFDPVAFSIRLRDIGSNFGVMPHITAKDRNLSALASELRTAQIFGFEAVLLTTGDWPG
LSMPSKPVFDLDSPNLIRLARFVFAGVLPPGERVPVDSRPRVAGAMSPHYRPRAEARRLI
RKLVAGAEVFFTQVVARKESVRAISETLREVERSYGADVPVVVSLLYPLRQEMKPFLERM
GIPTGNETFEVLLEEVKALDVKGGVNLIVVSKTVDEWLELWEEAKELIKEVFG
>A0A365H4D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura craniellae|TrEMBL
MRSVQPARTPTIRELLATGEKSFSFEFFPPKTEKGLHTLWDTIRRLEALRPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVNHSTAELRHLIGRFAGVGVRNILALRGDPP
GDPMGEWIRHPEGVEYAAELVHMIRSYGDFSVGVAAFPYKHPRSPDIESDTRHFVAKCRA
GADYAITQMFFRADDYFRLRDRVAAHGCDIPIIPGIMPVTKISTIERSEQLSGAPFPPDL
AAQFEAVADDPDAVRRMGIEHAAELCRELLDAGAPGIHFITFNQSTATREVYELLGVDGA
AASGSVAPMTA
>A0A5F0DWU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. MDB1-5|TrEMBL
MSTPTDSARTRRIPFSFELYPPKTDAAASALATTIDHLAAAGPDFLSVTYGANGSSRRSS
LDVLSRILRTTNVEAMAHLTCVGSTHDEANRLIREFLDAGVRSFLALRGDPPAGTKEGEA
FLGDFGSAAELVQLIHRVQAEKSPYRETIIPGIPAARAVKPGHEKVRIAVAAFPNGHPRS
RSSAQDIDTLLAKQAAGANLGITQLFFHADHFLSFVQRAREAGVLFPILPGIMPVTSPAR
LRRIIELSGEQMPADLSIRLEIEPTKEGQREIGIQHAVDLASQVIAGGAPGLHLYAFNQH
ETVLEVLDGCGLLGAPAPVRTPTALPTIV
>C0XTK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium lipophiloflavum (strain ATCC 700352 / DSM 44291 / CCUG 37336 / JCM 10383 / DMMZ 1944)|TrEMBL
MSFELIPPRHDADTALLDNLIAGLAEYNPDYVSVTSSRRSDWLEGTAALIKRIAETTDLK
PIAHLACTAGTRDELTEWIRTLIDAGVRGFLALRGDLPDGETQLPDGYLPHATDLLNLIQ
EVQDEQAFRLAAGKLALSVACYPSGHAESKNADMDLDVLLAKQRLGADFAITQLFFEAQD
YLDFVERSRLAGVRIPLIPGIMPMTSLRRVERMGVLSGITVPQRVTDRLSEASTPDEEYE
IGMAMSAELTREILDAGTGGLHIYTHNNLAVTRDLLSRINL
>A0A562Y7V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter lanienae|TrEMBL
MLKDKIKQGKSGIILYGLTPPKISLSSDEAKEIALKQLQRLEGIKIDGLVIYDLQDESNR
NSNNRTFEFVRTINPEIYAKDYLQNRYEAVIYKAVGNYDRDEFRDFLLTYNSSISVFVGA
SSANDTPKLSLNEAYKMKKEIANSLTLGGICIPERHMKKHNEDLRVASKRLKGCEFFITQ
AVYDIETTKRFLDDFAALGIKNTPIIFTFTPCGNEKTLEFMQWLGISISELSKRRIFDSN
DPLENSVKLSLDMFEFLYKYGQTKGVSVGANVESISTRKVEIEASIKLLKGIISIVENDS
LENTKSKIQSASRFDE
>C8PHR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter gracilis RM3268|TrEMBL
MLKEKIRNGKSGILLYGIVPPKITSSQDELERLGTAWSQRLGECECDGIVIYDLQDESAR
TKDERTFPFVHTIDPARYYTQYLHTDKEAIIYRAVGKYDEAEFCEILRHAASGLGVFVGA
SSKNEECKLHLSRAYEIKRLVAPHLCLGGICIPERHEKSRDEHLKIAEKTADGCEFFITQ
AVYNVQNAKDFIDDYAALECKKVPIIFTFTPCGSLKTLEFMKWLGISVPDFLQQRLQSSV
DILQSSTALCAEMFDFIYKYALAKGVSVGANVESVSTRRVEIEASLSLLKEIRKIILKHE
NLGFYVI
>A0A523W9R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MLSGDKPLGRQDTSKEVWEVTSTKLCEIVKSLNKGFAYDCGDFIKIDGKTDFFVGGAIVF
DRKDEVKKTAKKIDAGFDFFQSQIIFNHTDVLNSFQEAEKEGLIINKPVLVGFSPQPSEK
ALTRVFKFLHAEISEQLLNRLKRSDSFAEESILMYLEIADKLKSALSFKYKIGFHIMTLG
HDGLGRKIVEELRK
>A0A6H1FMW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cedecea sp. FDAARGOS_727|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWRSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELQTIAKDYWDNGIRHIVALRGD
LPPGSGKPELYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQSDLLNLKRKIEAGANRA
ITQFFFDVESYLRFRDRSVAAGIDVEIIPGILPVSNFRQAKKFADMTNVRIPAWMAQMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A7J3MJG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MVMESFNNLVFLAAPMFLSLEITPPKRDVERVMNIVKQAKDIIDAVNVTDTPLGQPRIPG
FIFSIMLKERLGIEPIVHYKTVNMNLTNLKSVLYGCVAAGVRRFLFMRGDNPAEGSSISD
ISPEGLSLWAKRELGVEVGLAVGWPTSIDKLVSKLSAKPDYVFTQIFLSVEDAEKFRRAF
EEAAGKAEWFPPVYCTYLVLCEENLPTLREVARLMGLEAPSFKLDMETNINFIHELERFF
EGFMISSPGGYEHAIRLVKSLRGL
>A0A7C7UEB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MKTVGEEKVFSNLMREIKAGKFVFTGELEPEKTTDLSEMVEATKPLKGYVVACNVTDGPR
ACAYMSSLVASYILQKETGVEMIYQLVCRDRNLIALTADLLGAGALGIRNVLALAGDHTS
LGDTPGAKPVFDVDSAQLTYLIRKMVDEGVDMYGIKIHNPPKFHVGVAANPNADPLEPEL
LKVERKVAAGAEFIQTQVVFDIDLTKRFLKEIEKFNTPTLIGIFPMKNYGIAKFFDQNVP
GVSVPKELLEKLKKISKIEDKKVRNEKYDEANLEFFVDFIKELKKTKAAGCHIMAVRYER
LIPKLVKAV
>A0A7J2TNU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MIIVQQKPLEEIFENTEKLQDLLVVGCDGCAAIIQVGGEKQAEILKTLLEMHRKIKGTNT
LRIKAISILRQCDKQIAASSLRPIIEDYGALISLACGVGVQTLADLYPDKLVIPANDTKF
LGMHDTKEGKFYEMCRACGDCILFETGGICPITRCAKSLLNGPCGGQAKGKCEVGGWKKD
CAWVLIYNRLKERNRLDQFTKFRIPRDYRISEHPREIDGETLITKKTEMPRDKEQLAKIG
RGKAYSELTKQIMEGKFVFTGELEPVKTTNLHEVIEGAKLLKGHVVAINITDNPTAFGYM
NALVPSYMIQREAEVEAVYQMTTRDKNRLALISDVLAAGALGIKNILVLTGDHTVVGDTP
QSKPVFDLDSATFTYMLRKIIDEGVDLNGNKIENPPKFSIGIAAAPNADPLEPEILKIER
KVKLGVDFIQTQCVYSVEQAKCFLDAVSYLKTPILIGVAPFKSLAMMEWMIKFVPGIKVP
PEVEQRLRRAKEKGKEAFQEENVEIFGAMIREIRKTTDAAGIHMMAVGFEWIVPKIIERS
GIA
>A0A349ATC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKYNGTAGILEERLKSERLTADGAFGTYYEKKYDTGSLPELANSQAPDRVLAIHKEYIEA
GAKIIRTNTFASNTVCLGQDFDEVRINIKNAVGIAREAVKGTDVLVAADIGPIPGENMIE
KEHLEKEYADIVNVFKECGVHIFVFETFSELGFIAKAIETVGNDGFVITQFAINQFGYSS
AGFSARKLIDEAGSNPYIDACGFNCGVGPGHMKKLVQSLINRNDKYFAVLPNAGYPQVVS
GRMVFADNNAGYFAQIMHDLAESGADIIGGCCGTTPEYISRMVLKNADVAHVKKFFADEE
TAEEKTVIDASFYKGKEGRKLIAVELAPPLGVDDEKIMDAAFLMKKSGVDVLTFPDSPSG
RTRADSILMAEKVSRETGMCVMPHICCRDKNAIAMRSQLLGAHINNINNFLVITGDPIPS
VVRASVKSVFNFDSVGLMNIISDMNQEQFADKPVIYGGAINQGRVNFNVELTRVKKKMEA
GATFFMTQPVFTDEDISRLRQIKEETGARILCGIMPFVSLRNATFMKNEMTGINVTDEIL
SRYRADMTKEEGEETGIQIAKEIIAKTIDFVDGYYFSFPFNRVHMLEKIIGKNQQ
>A0A537GQ68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MGCDFRETHQHCQGCRARTGGFTLRLSDAANNHPIVTVELIPDRVIPAHLPILQGRVDAI
TIPAFRNGEGDPSYPAGFRVTPQTRSLASAVIVRKTGAEAVPSLTCRDFRRSDLGLVPSL
FKKGLDNFLVVFGDPYPGHRIEDYDFRKTEDLIRGVLSVFDGPRPCIGAVTNQYAKDQER
ETARTLRKVDAGADYVVTNTAFDDRLVLDHVDKLRSQGLKAPIFVQVSIPSGLSKVRYPD
PRKSDSDSHS
>D0TLL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. 2_1_22|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAADINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>F4PLP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cavenderia fasciculata (strain SH3)|TrEMBL
MKIIDKIKKHKEENGATTPFYSFEYFPPKTMEGVQNLYDRLGRMLLLEPLFVDITWGAGG
STSELTLEIADTAQNICGLETMMHLTCTNMQVSQIDFALAKAKESGVRNILALRGDPPRG
EEWKKIEGGFAHASDLVRYIRQHYGDYFGIAVAGYPEGHSDATSLEDDLQHLKTKVDMGA
DLIITQLFYDVDMFVEFVGKCRAIGINVPIIPGIMPIHTYAGFKRMTTLSKTVVPQHILD
ALEPIKDNDEEVKKYGVNLCIEMCKQMVAAGVDGLHFYTLNLERSVRKVLKGLEMIRPDQ
LHRYLPWAQCASTNRLKEEVRPIFWKNRPRSYISRTGSWDEFPNGRWGDYRSPAFGDLSD
YHLSSHQFDPNATSATNVYGDVQSRQDVYEVFANYCKGDKVKKLPWNDLPLSVESEAIKE
QLVFLNSHGFLTINSQPAVNGVPSTDKTHGWGGKNGYVYQKAYIELFASPENMHLLIEIF
KKCPSITFHALNRKGDSHTNTKGTNAVTWGIFPGKEVVQPTVVDHSSFLVWKDEAFALWQ
SRWSSLYDENSTSRKVLDEMIDNYYLINVVDNNFVNGNIFQPFIDLVNGNMSPQA
>M6JRH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira santarosai serovar Arenal str. MAVJ 401|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSRLDPDFVTVTYGAGGSTRSK
TAQILSEISKNYSFPTVSHFTCVGANQEQILKTLKEIRSSGIVNLMALRGDPPKGEGQFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPNAKNLEEDVENLKRKVDAGADFLVS
QLFFVNSIFENFLNLVRTAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A509CAN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella sp. NCTC 3046|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2D4ZI95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinovum sp|TrEMBL
MSTPEISFEFFPPASLKDSFRLWNTINALEGFQPKFISITYGTGNKPRALTQDLVETLLE
HKDLTVAAHLTCVDMSAESTLNLVRSLAAKGLKDIVALRGDPAPDHGGAFRPHPLGYQTS
CEMIAALKNLGGFKIRAAAYPQGHPESRSQAADLDWLKRKFEAGADEAITQFFFEADDFL
RFRDACVKSGIDAPIIPGILPIENWTKTRNFAKKCGVSVPLWLEEAFERATRDGRHDLLS
TAIGTELCDTLRSEGVDTLHFYTLNRPELTRDICLALGLTAKPSLXAVA
>A0A1H4W336|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mohnii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>E3FGW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stigmatella aurantiaca (strain DW4/3-1)|TrEMBL
MKIRNRLNPSNPCFSFEFFPPKTDEGTENLLKTVEELAPLEPGFVSVTYGAGGSTREKTL
GLVTRIKQTTGIESMAHLTCVGHTRDELREVLQQLEAAKLDNVLVLRGDPPRGQTTFAPT
PGGFRYASELVEFIREEDFNFCVGGACYPEGHVETESRDEDLQHLKAKVDAGLDFIITQL
FFDNAFYFDFVERARRVGINVPIVPGIMPITNVEQVQRFTRLCGATVPMRLGLQLDRVKD
QPDAVVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMILGALRSRS
>A0A351PTC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKIVDIIESDKVTLSFEVFPPKTSGQYDEVSKAAMEIASLNPDYMSVTYGAGGSTKGYTF
KIASDIQKYFDVPTLAHLTCCLATKDSIKEALSQIKENDLHNILALRGDRPKGYEGDPFI
DYKY
>A0A2D5CK10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinovum sp|TrEMBL
MTPPQISFEFFPPKNLESSFRLWDTVQVLAPLEPRFISVTYGAGGTTRDLTRDAVSTLHK
SSGLRVAAHLTCVNASRQETVAVARSFAAAGISDIVALRGDPPKGVDGFTPHPEGFQSSL
ELISALAQSGDFTLRVAAYPESHPEAESPAADIEFLKRKIDAGASEALTQFFFEAETFLR
FRDACDKAGINVPITPGILPIENWQGTRRFAKACNAKVPNWLTDAFSKAERDDREDLLAT
AVCTEXCSQLIDEGVDTLHFYTLNRPDLTRDICHALGITAAVKLEKIA
>A0A0Q6RWP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Root1204|TrEMBL
MAHFDENPLGRHLPLDPVPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNSKFLSGRKLTTPPQVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMSKVRDLGFDEKCFILVGV
GPLASAKTANWIRNNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIKGVSGVH
VMAYRQEEYVAEIVHESGVLKGRTPWTREANPGDSRVAERLDAIRDGKQENQQEMADVAA
HRQH
>R5C2R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia hydrogenotrophica CAG:147|TrEMBL
MKITELFERGEFVVSAEVGPPKGIHIEHLLEEAKTYLSGITAVNVTDNQSSVMRLGSLAV
CKALKDEGLTPIFQMTCRDRNRIALQSDLLSAAMLGIENLLLLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVRKLEEGEDLGGNKLVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVRAGA
DYFQTQAVYEPEKFIKFMEKAKQFGKPVQLGIVIPKSAGMAKFMNDNVAGIHVPQEMLDE
LKKDKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAGL
>A0A2D2AW06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter mirabilis|TrEMBL
MSSAPAARRVIGPVARSGERAARPLGISFEFFPPKTPEMEANLWSAIRRLEPLAPDFVSV
TYGAGGSTRERTHRTVKRIIDETSLKPAAHLTCVEASREEVDEVIREYWAAGVRHIVSLR
GDPPSGIGGVYTPRADGYANATELTQAITAINPFEVLVGVYPEGHPESPNLAHDIDVLKA
KVDAGATRGISQFFFDIDAFLRFIDKARSAGITIPISPGIMPVSNYKGLVKMAAACGTSL
PSWLGNLFDGLDDDPETRRLIACSVAAEMCAKLEEQGFSDFHFYTLNRADLVYAICRVLG
VRETASSSSEAAA
>A0A7I8MT64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis associated proteobacterium Delta 3|TrEMBL
MQLKDKFERGEFAVLAEMEPPKGVDVTGMTENAARVKGKVDAFVVPEMSNAVMRMSSLGG
AMVLQGRGLETVFQVCCRDRNRIAIQADLLAAYGCGITSVMAVHGEDTSFGDHHQARSVY
DIDLLDLLRAIRGLEEGRDMAGIELAGAPEFLIGSRIDAAARDRSPELEADEIRKKVEAG
AEFFISPPVFDLSVIEPFQERFQTDGVKIIPTVLLLKSVGMARYMARNVEAVYVPDEVVT
RIQKAPDKVNECVALAADLVRRIKDAGYAGVLIATIGWEQKLPGILEYL
>A0A521TG08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcaceae bacterium|TrEMBL
MSADKMAERFLDALRDHPLVADGAMGTQLYERGVLYTQNYEEICVTRPELIKSIHRDYLR
AGAQVIETNTFGANRYRLAKFNLEKRVKELNEAGVRVAREAVAESTAASAWVAGNIGPTG
LPTLKGLTGRDLAEIRSAFEEQAAGLASADLITIETMRSPEEMRLCIEAVRASTDLPMVA
MVSFDAFGTMADGTTPEAMADRLAQWGADVIGVNCGDGPAGVFDTLERMRGAGLPMAAMP
NAGIPRRIEGRMLYMANPEYFGVYARRLIKLGVRLVGGCCGTTMDHIRRAANAARMHAHE
GAAVSEGGSIRTSGGGAQEPNDPTMSGAAIEPAPGARVVPLAERSPFAAKLGKQFVVSVE
VNPPAGMDPGKAVAAAKHLLANGVDVINIADGPRASARMGNLALAVKLIREGVEPLLHVC
CRDRNTLGLVGHVMAAHELGVRNLVIITGDPPKMGDYPDCTAVYDLDSIGLLRLVRGLNH
GRDPGGKALGGVTQFVLATGAEPAAMDYAREIARLKKKVEAGADLVMTQPVYDPAVLTRF
LDDVEPWGIPVMVGILPLASYRNAEFLHNEVPGMRVPDEVRERMRKVGSGPLARKEGVGI
AREMLLAVRHRVAGAYVMPPLERWEMALEVIDGVK
>A0A286GT68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. DSM 44270|TrEMBL
MKRALTVRDAATRNSLRRAFDDLGYEVIPFKKTEQAVLDSVPKDVRLTVTASPAKGQDVT
IDLTVALVGHGYTVAPHLSARQVRDRAHLADIVARCREAGITDVFVVGGDPTEEPTEFRH
AHDLLVALHELDHGFTEIGIGGHPEGHPTASTETLFQALKDKAPLATHIKTQIVFDPVVI
LEWARELKNRGIELPVHVGVPGAVHRQKLLRVSGGLGIGESAKFLKKQQNLFWRFFIPGG
YSPNRIIKGLAPHMGKPDNNIEGFHVFTFNDLGPTEAWRQQMLKSLG
>A0A286H4T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. DSM 44270|TrEMBL
MPPGSARPRTAPVPSMSVTRTIRELLASERPTWSFEFFPPKTPEGAAQLWTALRELERLQ
PSFVSVTYGAGGSTREGTMQVTERIATDTTMTPLAHLTAVDHSVAELRHLVSRLAAAGVR
NLLALRGDPPGADPQAEWRAHPEGLNYAGELVELIKSMGDFSVGVAAFPERHPRSPDFDT
DVTWFVDKCRAGADFAITQMFFHAEDYLRLRDRVAARGCDVPIIAGVMPVTNARQITRIV
QLSGQAFPQELADRFAELDGDRPEDKAAVRAYGVEVASDLCRTLLAEGVPGIHFITMNRS
TATREVYANLVGAPAIS
>A0A7C6YEH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MLNLIAGSNLERVLTSGQFAVTGELGPPKSADITSLRHHGEALRNYVDAFNITDNQTAIV
RTSSIACGAVLVQMGLEPVIQITVRDRNRIAIQSDVLGAVALGIKNILCLSGDHQKFGNE
PQSKGVYDIDSLQLLNGLRGMRDEGKFIGGEELEAPLTYFLGAVANPFADPFEYRVDRLE
KKIQAGASFIQTQCIFDLPRFKKWMELVRERGLHKKVAILGGVTPIKSLGAARYMKNNVS
GIIIPDEIITRLQGAQNKKEEGLKICIETIQQLKEVEGIAGVHIMAIAWEEVVPEIVERA
GLYPRPDL
>A0A7C3MSE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MKDFREFLKEKEVILFDGATGTELLNRGYPQDKPIEYANILNPELVISIHREYIEAGAEC
IETNTFGANELKLRSWGYENLVEKINKMGIKLAKEASNKNIYVFASIGPIGKPIGKGFEI
DEKKAIDIYKRQIISILEEDPDGLILETMSSTKEVEIILRLLDNLSVKIPLIVQFSFFKD
MSTVLGEDIHRVIEFLKGIDVDIVGLNCGNGPLQTLEILKIFAQHLKEPFSVQPNAGYPQ
FIQGRLVYNTGETYFASFVKEYIRYGAKVIGGCCGTTPRHIAFIKKETKRDLLVEIETET
IHEKEIEIKKKDTPSRLSRKLGKEFLVSVEISPPKGIELEKVKEGVKLLKMAGIDAVNIP
DSPMARVRISSIALAHILKEELDIESILHFTCRDRNLIGIQSELLGASALGIKNILALTG
DPPSIGDHPQAKPVFDVNSEGLVLILNKLNNGIDYMGNPIGLATNFTIGVAVNPNTDNPE
QEIGKLKRKIENGVNFIETQPIYDKESLERFLERIEFKLPPVLAGILPLRSSRHAEFLHN
EVPGISIPKNIRERIKESKDPKREGIEIAIELIESIKNIVNGICLILPFERYDVVAEIIM
GFSR
>W0L8Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chania multitudinisentens RB-25|TrEMBL
MSFFHANQREALNQNLAELSGQINVSFEFFPPRTREMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLDAAPHLTCIDASPAQLRDIASDYWNSGIRHIVALRGD
LPPDGGKPEMYAADLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMNSMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVI
>A0A7I8MXG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis associated proteobacterium Delta 3|TrEMBL
MFNFPYIVELLSPKRATDVPIEDLMDRFARRYQRIMDAGCGVSIPDNPMGQPRMGALESI
LAKRLSIDPEKVVMNLNTFHTKNELDDLLQHAAENDLKYILVIRGDGGPLLPKLAPKSIG
GNQSIATSIDLIRYINTVYSGRFVTGVAFNPYKPMPFELERLNRKIEVGAQYVVTQPLIG
KDAHVDKLESLGIPVVIEAWMSKNIDLLYKSVGKANDKDTETFDPVENLNKLHDTYPNCC
VYLSMLSFKQDWHAILPRLRH
>A0A399T525|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribellus luteus|TrEMBL
MKVIDTIKAAKSTVFSFELLPPLKGNDASKLYQTIESLTEFDPKYINITTHRDEVEFKEM
KDGSIVKRTVRKRPGTVAIAATIQHKYNIPVVPHILCGGFTKSETEHVLIDLNFLGINNV
LALRGDGIKGQSVFHPTENGHANANELVEQIKDLGKGKYLDGDLKNNMPLDFCIGVAGYP
EKHFEAPNMDSDMDYLKQKVDAGADYIVTQMFFDNQVYYDFVDRCRAMGITVPIIPGIKP
INLVNQLTVLPKIFNIDLPMELSKELAKCKTNDQAQKVGTEWAIYQSKDLVAHKAPSLHI
YTYGISDNVKEIVKAAF
>A0A0S7LLP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poeciliopsis prolifica|TrEMBL
MVNQVQQVDGSWQSCRGDSSGNSSGESSKESSRCSTPLLDADRSDRLREKMRKRMDSGDQ
WFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVN
YCGLESVLHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGDDWEDEEGGFNFAVDL
VKHIRSEFDEYFDICVAGYPTGHPEAESYEQDLQHLKEKVDAGADFVITQLFFRADTFLK
FLDDCRAVGITCPILPGIFPIQGYQSLRQLVKLSKLKVPEEITKIIEPIKDNDAAIRNYG
IHQAVDMCRVLLDSGKVPGLHFYTLNREVATLEVLRQLGLWVEDPRRPLPWAVSANPKRK
VEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALL
QMWGEELKNEQSVFEVFTCYITAQPNKNGQKVLCLPWNDEPLAPETNFLKDELEKVNRRG
VLTINSQPNINGKPSADPVV
>A0A4Q5ZAQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcaceae bacterium|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTVEELAPLNPGFVSVTYGAGGSTRDRTV
ELVTHIKQHSGIEAMAH
>A0A3G2FKR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. 3ACOL1|TrEMBL
MSFYHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGGGKPEMYATDLVTLLKDVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAVVG
>A0A4P1K7D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas vancanneytii|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRSAVNVSFEFFPPKSDEAEANLWKAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIEGYKAIGVDH
IVALRGDPPGSAGIGGAYTPRADGYANATELTAAIASIGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLKRMT
AACGAALPDWLAGHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAVA
>A0A8B2HWX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilus sp. K4|TrEMBL
MSIIYEVNPPKIPTGLDESSKEVNESLEKLQQRVSSISTLCDGIHITDSVLGTKRVSALT
TGEILKNNHPHLKITISLRVRDRDMDEIKDIVRKSIGLGLDGILVLMGDPSKTNPYESGL
VPSQVVKELNKEFAEKIDFFLSLPSNPNFEKIQKKIAAVPIGFITQVIHSSKQVERISEK
LRLQGFRIMPCILLPSEKNENSAKFLKLDWSEYKKDPASFIKQIHQIAGDVLITSPSDFT
FAKETLEKI
>A0A6I6ISS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius faecimaris|TrEMBL
MKLSHIAAPATRGQHLFQRIITMKTPRVSFEFFPPKSLEASFRLWDTVHALAPLEPRFVS
VTYGAGGTTRELTRDAVGTLHASTELNVAAHLTCVEASREETLAVADSFARAGVSEIVAL
RGDPPKGSDRFEPHADGFANSCELIEALADTGKFTIRVGAYPEKHPEATSRKADIDWLKR
KIDAGAAEAITQFFFDPETFFRFRDDCAKAGIDAPIIPGILPIEDWSGVRRFATACGTSI
PAWLDEAFDKAVRDGRHDLLAIAVATELCSDLIEGGVEDLHFYTLNKPDLTREICHALGV
TPRVQLQNVA
>A0A7S2TUU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lotharella oceanica|TrEMBL
KLKVDAGADFIMTQLFYDVDLYIDFVKRCRKAGITVPILPGLMPINSYNAFKRMIAYTKA
TVPKEIIAAIEPIKNNDAMVKAFGIELAKKMSQKILRTGLTPGLHFYTLNLEKSVTKILG
GLGLARLPSKGVRPLPWKQSCATRRKNEDVRPIFWANRPYSYLSRTISWDEFPNGRWGNS
TSPAYGELYDYHLMGLKSSSVRDRRRMWGGEVKSEQDVFDKFSEYIEGKISRLPWCETGI
MLETLPLKQRLMAINRTGFLTINSQPRVNGARSDDEVVGWGDPDGYVYQKAYIEFFASPE
RIKALKALASNKEYKTLSYHAVNAKGDQFSNYTDKNAVNAVTWGVFPGREVLQPTVVDMG
SFRVWKDEAFALWISQWRSIYPSGSASWEIIQKIHDTYYLCNIVENDFVKGGLDKFMDEL
AGYNPATEKNDGSAAAVA
>A0A7Y8LPC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
PDELIERMKSVPKERQAEEGIRICVETIQRLREIPGVRGIHIMAIEWEEKVSEIVKAAGL
LPRPQP
>A0A7Y8HGR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MSPNRFREALLEKKQFVYTLELVPGRGAKGKILEEAMKIAEKAVKGNLIHALSITDNAGG
HPALFPNVLGREICGMGMNPVIHFTCKDKNRNQIESILYALDRIGIENLLVMTGDYPLYG
FEGKAKPVYDLDSIQLLHLIKTMNEGKCIDGKAPGGGAECLPTHFLKGCAVSPFKMQEEE
VLAQYFKLCKKAKAGADFIITQVGYDARKFDEVLRFMRQQGIALPIIGNVYVLNRPVAKV
MNRGDVPGCVVTDSLYRLIEEESRAPDKGKVARLTRAAKLVAVLKGIGYQGVHIGGPNLK
YEDVEWLIEKSKEYSAAWDSLVREFSFPQEKGFYLYMEDAKTGLNTDVPNFKRIHPRKKW
GYRFMRFLHHFMFVPGAPLFKTARCFFQKIDGSRAEIPFTELEYWIKFASSRCQRCGDCT
LSEMAFLCPQSQCAKFLLNGQCGGSRDGWCEVFPGKKRCIYVRAYRRLRAYREEESMEDG
YIPPRNWDLSGTSSWANYFLGRDHQGIKQ
>A0A3G6UU11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. FJAT-42376|TrEMBL
MGFLEDLQNEILIADGAMGTLLYSHGIDRCFEELNLSSPDQVQGIHEAYIKAGARVIQTN
TYGGNHIKLSRYGLEDDIRAINSKAARLARKAAGTHAYVLATMGGVRAFKKSSHTLDELK
RSFREQLYVLLNEDIDGLLLETFYDLEELQTVLEIARKETNKPIVANVSLHETGVLQDGT
PLEMGLKNLEALGADVVGLNCRLGPYHMLESLEEVPLLDHAFLSVYPNGSLPSVEEGRLV
YESDERYFAESALAFRNQGARLIGGCCGTTPKHIQAMADALRGLAPIKEKSVKLRKPVTV
HERLEPAYPPLHQIVKERRSVIVELDPPKTLGLEKFFKGAEELKKTGIDSITLADNSLAS
PRVSNVAVGTQLKEKHDMRPLIHLTCRDRNLIGLQSHLMGLHSLGLTDVLAITGDPSKIG
DFPGATSVYDLSSFDLISLIKQFNEGLSYSGKALGGKTNFTVAGAFNPNVRHLNKAAERL
EKKIACGADYFISQPIYSIEQMKEVHDAVKHLSAPLYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIRETMAKAGGDPLQSKKEGIAIAKDLIDAAFDLFNGIYLITPFLKYEYSVELAEYI
REKEKQRSEREFSHVHHS
>R5JIU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. CAG:782|TrEMBL
MAGQTHEAFDPCDTGLLSVRKNDPTHKIIAVELVPPVNADDEKLLDAANILKNAGADVVT
FPDSPSGRTRADAVLMAEKVKNETGLRVMPHICCRDKNAIAIRATILGARLNGIEDFLVI
TGDPVPVMIRQTTKSVFNFDSIGMMNIISDMNEEILKSHRVSYGGAINHNRVNLNIEIER
VKKKMKAGATFFLSQPVFSARQAEILKGIKEQTGAVILVGIMPLVSRRNAMFMKSEMSGI
NIPDEVINRYPEDGSREEGEAVGVALAKDIMAATEDFADGYYFSFPFNRVGMLKKIME
>A0A1H2X7A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda zhangzhouensis|TrEMBL
MKITDHIKKANGETLFSFEIVPPVKGKSIQELYNNIDPLMEFKPPFIDVTTSREEYIYKE
KDGLLDKKLTRTRPGTLGICASLKHKYDVDTVPHVLCGGFTREETEYLLVDCQYLEIENV
MALRGDARKEEKYFTPTKGGHQYATDLVKQIQDINEGNYLHETFESSDLGSFCIGVAGYP
EKHMEAPSLQSDLKRLKEKVDLGADYIVTQMFFDNQKFFAFVKAAREMGIDVPIIPGIKP
IAVKKHLQLLPHVFSIDLPEDLINAVEECKDNKAVRQVGVEWAIQQSKELREAGVPVLHY
YSMGKSDNVMAIAKELF
>A0A2G5Q2F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium sp. N4G05|TrEMBL
MHSPMFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVS
EYGIPSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFEHASDLSV
YIRQQRPGMKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KARTAGIDVPIEAGIMPVMNVKSVLNMSSKCQSKIPEKLGIMLDKWGSDKALLKEAGIAY
ASEQICDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A5P8MC85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella suis bv. 1|TrEMBL
MEQRLWETVTRLAPLQPDFVSVTYGAGGSTRERTVRTVARILKETDIKPAAHLTCVDATC
EDVDRVAREFAALGVNRFVALRGDPANGIGEKYVPTPGGYQNGAELVGGLRNIADFDISV
SAYPEKHPESPDFATDIDMLKRKVDNGATRAITQFFFENDLYERYVERVRRAGIYIPIVP
GVLPVHNFKQVRNFCARSATHIPAWLAERFDGLDNDPQTHQLVAAAIAAEQVMDLIERGV
QDFHFYTMNRADLPFAICHMIGIRPKTQAALEVA
>A0A4S5BNP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lampropedia aestuarii|TrEMBL
MNSTPTSTRRTPVSLEFFPPKTDAGADKQRQARADLYALQPEFCSVTYGAGGSTQEGTFR
NVAEILAEGQQAASHFSCIGATHEKVRTELQQLKAMGVQRLVALRGDLPSGYGLGGQFHY
ASDLVAFIRAETGDHFHIEVAAYPEMHPQAHSPKQDLQAFASKVHAGANSAITQYFFNAD
AYLRFRDEAQALGLAIPIVPGIMPIMGSSQLLRFSDACGAEVPRWMRTRLQSFGDDSASI
RAFGLDTITDLCARLIREGVPSLHFYTMNQSPLVLEISKRLNLV
>A0A503I3B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-4-19|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVGRILNETSLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSTRCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A503I0H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-4-19|TrEMBL
MSARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKSRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A0J9BZ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] citroniae WAL-19142|TrEMBL
MKIRDILAQGRPTLSFEVFPPKTEDAYDTVERAAAKIATLKPDFMSVTYGAGGGTSDYTV
GIASDIQKSGVTPLAHLTCVSSTRDKVHSVLEELKNHGIENVLALRGDIPADGRTPREYH
YASELIHEIKQSGDFCIGAACYPEGHVESANKSVDMDYLKEKVEAGCDFVTTQMFFDNSI
LYSYLYRIREKGITVPVIAGIMPVTSAKQIKRITQMSGTYLPSRFLAIVDKFGDNPAAMK
QAGIAYATDQIIDLIANGVRGIHVYSMNKPDVAMKIRENLSEIL
>A0A6A8QGT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Telmatospirillum sp|TrEMBL
MQQSLWDCVTRLAPLAPAFVSVTYGAGGSPRERTHETVTRIAREPDLQPAAHLTCVGASR
HEVDSVAEQYWQAGIRHIVALRGDPPEGQGVYRPHPEGYPYAVDLVRGLKRIADFEISVA
AYPETHPEAASPEADLDNLKRKIDAGASRAITQVFFDVDLFFRFRDRAARAGIAVPLVPG
ILPVTNFAQASAFARKCGAAMPDWMASLFDGLDGDPDTRRLVAATVAAEQCRALVAGGAE
ELHFYTLNRADLTYAICHILGVRASRAGA
>A0A3N5ANQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfitimonas autotrophica|TrEMBL
MRISKIYAAYKPVISFEIFPPRTEDRADIVSRLAADFRKLGPAFISVTYGAGGTTRDTTV
EIASLLSGFGFTVMSHLTGVGHTVKEVDEVLARLHAAGVENILALRGDPPRETANVYTAG
DFAYAVDLIRHLRSKGVFGIAAAAYPEGHIESPRIDLDWRHLKEKVDAGAEFLVTQLFFD
NRVFYHFLESIRRMGIFCPVTAGILPVLNAGLLKRIVSLCGASVPAKVLGLLDRYADDPV
SLEKAGIEYATAQVADLIANDVDGVHLYTLNRPEWVTQLLNNIGYKRREYLPASQAGLAR
>A0A7X4IIR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0675_bin_23|TrEMBL
MHIAEVFRQSQPAISFEFFPPKSEAASESLFHTIQKLIPLKPAYVSVTYGAGGSTRDLTH
DLVVKLHNETNLTIVSHLTCVQSSRDEIFRILQRYDEHSIRNIMALHGDPPSQEPCDPSG
QDFRHAVELVAFIKKHFPHMGIGVAGFPEGHPDTPNRLQEIEYLKAKVDAGADYVCTQLF
FDNRDFYDFCERCQLAGIHVPIIAGIMPITSLQGMKRMAELALGARFPGRLLRALASAKD
DAQAEKIGIHWATEQVLDLLDNKVLGVHLYTLNKSRASLQIYETLGLQRVDMLME
>A0A2R6H8J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QS_4_69_34|TrEMBL
MSLETPSTTATDGVRELLAEPRYELMPFDSFGDQLELLPEGATVAVTTSPTLGLEATIEW
TERAAEQGYEIVPHVAARYVRDEDHLEEIARRLTDAGVTDVFVPGGDREDPVGKFDSAHA
LLAALDGLDYGFEEVGITGYPEGHAFLDEATLADAMARKAPYATYVVTQLCYDPEAVVGW
IETIRERGIDLPVEVGIPGVMNYGRLLEISRKVGVGDSVRFLRKTTGIVGFVRQLVGSRG
KYTPDALVEGLAPYAADPDYGVRGLHIYAFNQVSDLETWRRETMEE
>H5WSQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium JOSHI_001|TrEMBL
MSTQTPRLPVPVSFEFFPPNTPVGAEKLKTVVQDLGALAPEFFSVTYGAGGSTRDKTLAT
VKDIAVAGFEAAPHLSCVGSTREGIAEILATYRAQNIRRLVALRGDLPSGTAVAGEFRYA
SELVQFVRETQGADWHIEVAAYPEYHPEQRYAKRDLQHFAAKVKAGANSAITQFFFNPDA
YFHFVDEVRALGVDVPIVPGIMPIHNFARIVQFAARDGIEIPRWVLLKMEGYLDDTASIR
AFGVDVVTRLCERLIAGGAPSIHFYTLNQSGLTTEICQRLMGR
>A0A8H7ADI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endocarpon pusillum|TrEMBL
MEKITDKLAALPPNTNYFSLEFFPPKTQAGSSNLQARLIRMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCMHLTCTNMSRALVDEALDEAKALGVRNILALRGDPPRSEE
YHMDDQENSNKDFTWAVDLVRYIRKVHGDYFCIGVAGYPEGHADDSHPEHQSVERDLPYL
VEKVKAGGDFIMTQLTYDVEAYTRYEDTLRSHPSGIFTSIPIIPGLMPIQSYQIVKRITN
LSHARIPAEMLSRIEAVKSDDEAVKRVGVDILSELVEGIKALPQPKSLPRGFHFYTLNLE
KSVAFILERCKLIPSSTEPTTPSTSDSESEIAITTMPTGPTMVINGTGELSKRRFSRRRA
SSFNSQPHNRLIVDSVSARDVGSRHRLPSGAQSSQGSETHQTPSECAGIPAGPSTRSNTL
LISEGQGSLGREATWDDYPNGRWGPSSSPAFGEIDGYGPSLKVGPVAARRLWGHPKSPDD
ITGLFRKHVEGELVCVPWSDETDVTSGGPLRAETEIIRPQLIALIEGKRFWTLASQPAVN
GIKSDDEVFGWGPPGEGFIFQKAFVEFFVSRQSWEKEVRPLLQMHGEDELSWLKTDNEGA
FESSASAEMVVDPTTSKPAAGATGINAVTWGVFRGKEIVTPTIIEEQSFRAWGEEAYGIW
EEWRRVFPRGSEEEKFLESCKRDYVLVNVVGQRFVGKDGARLWEMLALR
>A0A0K1HH52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter ureolyticus RIGS 9880|TrEMBL
MIPYQGLRKSKILICYHTKNNLRKNMFFEKLKNNESGILLYGQTPPKQNHQNLENLLELR
KKRLNLLDVDGIVIYDLQDEGDRNDEKRIFDFVTTINPYEYYKALELKFPGIIYKSVGKY
NQDEFIKSLKFDKNIANVFVGASSKDQKIKLSLKKAYEIKKEFAKDIPLGGICIPERHEI
KHNEHLKVANKTLNGCEFFITQAVYNAINAKNFIDDYAKLNIKKVPIIFTFTPCGSLKTL
EFMKWLGISIPPFLENRLKNSIDILQSSVSLSFEMFEFIYRYAKNKGVVVGANVESISTR
KVEIEASIKLLKDIKRSIDRKV
>A0A2I0EWC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. Sarcosine-02u-2|TrEMBL
MTKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRGRTLDIVQALCA
RGDTDIAPHMSCIGDDKSQIAELLDLYKSLGITRLVALRGDLPSGQVGMGELPFALDLVK
FIRKHSGDHFRIEVAAYPEMHPQARSFEFDVDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTVAQPLVAGIMPITNSSNLVRFADSCGADIPRYVRKRLADFGDDRAAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVEALGLIA
>A0A396CRY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM16-21|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>B5HIQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces pristinaespiralis (strain ATCC 25486 / DSM 40338 / CBS 914.69 / JCM 4507 / NBRC 13074 / NRRL 2958 / 5647)|TrEMBL
MSTLREILAAPGPSFSFEFFPPKTAQGERTLWNAIRRIEPLAPAFVSVTYGAGGSSRDRT
VAVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGVHDVLALRGDPPGDPNAPWT
AHPDGFTHAHELVSLVRRSGDFSVGVAAFPERHPRSADWDDDIRHFVAKCKAGADYAITQ
MFFHAEDYLRLRDKVAAAGCDTPIIPEIMPATDVKQIARFAQLSGATFPAHLAGRLEAAR
DNPAEGHRIGVEYATAMADRLLAEGAPGLHYITLNRSTATLEIHQNIQNSRSAHALAAGR
>T0PWR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprolegnia diclina (strain VS20)|TrEMBL
MKIIDKIRAKLEKDETFYSFEYFPPKTQAGVTNLYSRIDCMAQMDPLFCDMTWGAGGSTD
KLTLEISANVQKFSGLEMLMHLTCTNMSRGSIKNALDAAKDAGIQNILALRGDPPRGKTT
FEECDGGFSYALDLVKYIRQEFGDYFCIAVAGYPEGHPDSTDLEQDLRYLKEKVDAGADF
IVSQLFYDAKIFLGFVERCRAIGITCPILPGIMPIQSYLGFTRMSAMCCKTIPAAIHEAL
APIKDNDEAVKDYGVTLGIQMCKELLEAGVAGLHMYTLNLERSTRLILEGLDLISSARRE
LPWRPSTMIKRVSESVRPIFWANRPKSYLDRTSSWDEFPNGRWGASESPAFGDLSESHYM
HATHSVADRKAMWGDALTSLDDIYETFTRYCMGALKSLPWCDTPLHLETKSIQELLAGLN
RAGFLTINSQPRVNAAPSDDPMFGWGGPGGRVYQKAYVECFVSPANLKHIIEKVSKLKWV
QYHAVDVHGNSYSNVGKGTTAVTWGSFPNKEILQPTIVDTDSFMAWKDEAFSLWLSMWAS
LYAPDSTSYGLLKEVHDTFFLVSIVDNNFVNGNIWDVFEQTTTDAATTP
>A0A836QPY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MGHNDRAALEVSFKFFPPKTEKTVERLWRSVDRLAPLRPRFVSVTYGAGGSTRDRTHAIV
AHLRRNTDLEPAAHLTCVGASVDEVNAVVRDYYAAGVRHIVALRGDPPEGESKFTPHPEG
YDGSVELISGLKTIADFEISVGAYPEPHPDSRGMQSELDYLKRKLDAGATRFITQFFFDN
DCFLRFLDKVRGAGIEAPIVPGILPVTNFQQVARFSSMCGASIPDWFGSRFDGLDDDPST
RQLVAAHTAADQCFGLLESGINEFHFYTLNRADLVFAICHMLGVRAGPTAATGAD
>A0A7Z0LX31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas glaciei|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTREVVR
AVGESGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRTETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKVVDNLTD
>A0A6S6P6I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium litorale|TrEMBL
MSTDLRCPKRMEFGPCGGVRPDGQCEMRPGPCVFPEVVPWSGVEPAPRPAAAPLVLTDFS
CAPFDRADVAATAALLTGSCDAVLVGEHQNRPDFPPTLMGRLLLDAGVSPWITLSCRDRN
RIVLEQELRGLRTLGVGTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGMVAAVP
ETPTAPPVHRRPARLVEKQRAGASLAVLNHVPYPATVADFMASARAAGLSIPVIAAVAVF
TDVVSAAVLQGLPGLALDQEVVDEVLGAADPVSAGIAAAVAEARALLAIDGVHGVNLSGS
ATASGTRAGAEIKAEVGRLINAGEAA
>A0A6N8S1U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia sp. CH05|TrEMBL
MSFPISFEFFPTKTPEGATKHVQVRKNLYARKPQFCSVTYGAGGSTQTGTFAMVRDIQNE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPQSDLDAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A6N9BF33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MGGAPSLTGLRTLPQAAGGRRSIRDIEYACHDKLSHRGNSSSRADCKRPPGRGTFAGMKI
DGFSIETTPGGARKVGSFAALVPQGTRVFITHLPDGALDDIVRTAARLAGAGMAPVPHIG
ARHLESRAALERHLDALRSLGAREALLVGGDRSGPRGPFSEAGDLTGPAAERFERLYFAG
HPEEDRDAALLAKIAAARTAGAEAAVVTQFVFEAEAVLNWVERIAGLGNTAPIRVGLPGV
ASPGALLKYAKMCGVGRSLRGLWRDGRLLRMAGRWTPAAPIAGLDKAPPAVEGLHFFPFG
GFAETAAYLAEARQAPSERRWNQS
>A0A7C9GGA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MIQTAPHTLTVPDRAVPAGIEVSFEFFPPKTEKMEETLWASIARLAPLGPRFVSVTYGAG
GSTRERTHATVVRILKETSLTPAAHLTCVGASCAEVLEVADRYWDAGIRHIVALRGDPPE
GQTYEAHPAGFAYAVDLVKGLRDAHDFEISVAAYPETHPQAPSPAADLDNLKRKIDAGAT
RAITQFFFDVDLYFRFMDRVQAAGIAVPVVPGILPVTNFAQVTKFAGLCGAAVPGWLARR
FEGLDEDPETRRLVAATVAAEQCRALQDGGVREFHFYTLNRADLTYAICHILGLRPRTKV
RA
>A0A7V9MY35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSLENLITNPGPLQVSFEFSPPKTDEAEAALWLAIRRLEPLAPAFVSVTYGAGGSTRERT
HATVKRIVDETSLKPAAHLTCVGAPRGEIDDIVRAYWDAGIRHIVALRGDMPGMSGPYTQ
HPEGYRSTPELIAGIRKIADFEVSVSFYPERHPDSPSHGHDIDLLKAKMDAGASRALGQF
CFDNDLTARFRDDAARAGITIPVVPGIIPTTNFNAVARMAGKTGASIPAWLTKAYEGLDD
DVETRRIVAAAVLADQVQQLRTRGFGQFHFYTLNQANLTYAACRILGIRPSHL
>A0A2W4IVX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus dendritiformis|TrEMBL
MKDLRQVLQGEIIVGDGAMGTYLYQLGYPVGISYESLNISEPERIRDIHREYVSAGARLL
ETNTFTANREKLSKHGMEKQVKAINRAAARLAREAAGGQAYVVGALGSIRAGKRENIETD
QVKRDYTEQLSALLEEGVDGIMFETFYDMEEMKLAVQIVRALDDRIPIICQFAVEESHRT
KDGLRLLDAFRLLREEGADVVGLNCRMGPNGLMRAMEDLTGRLALPMSAFPNAGLPDYVD
GRYNFVATADYMAESAVRFAELGARIIGGCCGTTPEHIQAIAQALANAPAPALPTLAEEE
AQVQAVLPLEIGERGAAPASGQGKAASGPSLVDTVRERHTVIVELDPPRDLDIAKFMLGA
QALKDAGADALTLADNSLAVTRMSNMALGYLALDKIGIRPLIHIACRDRNLIGTQSHMMG
LDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEIIRMIKQLNAGLAFSGKALKQRANF
VVGAAFNPNVKHLNKAIERLERKIEAGADYIMTQPVYDASLIERIAEGTKHLNVPVFLGI
MPLASGRNAEYLHNEVPGIHLSDEVRERMKGLEGESGRREGVAIAKELLDVAMKHFNGIY
FMTPFMFYEMTAELTEHVWQKAERLTDPLYRHT
>A0A432J272|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MEYQSLLHKKLSEGIFVFTAETTPPDASNQEVLLKKTMPLKGVADAVNVTDSPGAKVHMS
SLTAAIILAQNDIEPILQLTVRDRNRLALQGDLVGASALGVHNILCLSGDDPKVGDQPET
KPVQDINSATLVSTANMMRKDKQFPSGRIIDPPPKLFIGGAEVPSKGKPNTKKILNKIKI
GVDFFQTQYIFEKKKLIDYMKVLDDVGILEKTYFLIGLGPFASAKSAKWMNDNLFGVDVP
DEIIKRLEQAKDQKEESKKICLELIQIFREIKGVKGIHLMGHKKEELIAEIIKESKIS
>A0A222SSZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 11-1-2|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRAELRNIIGQYADAGIRNMLALR
GDPPGDPTGEWIRHPDGLDYAVELVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPLTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATEVCARLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>A0A3B9FFR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MAASIQQIRQAAEGWSIEVTPAGATKIDSFAACLAPGTTVNVTFLPGSDPLETVAVTKRL
HNEGMKAVPHLAARSLRDADQLDTLLAAYRAEAGVDEVLVIGGGVDKPVGAFDNSMQILE
TGLLQKHGIMTAGVAGHPEGSPDISEAEIADALAAKNAFAKREGMTLYIETQFCFEAPIV
LEWEKRVRAAGNELPIRIGIPGPATIKTLFRFAQISGIGPSMRFISKQARNVAKLMTVQS
PHLLLSDLAQGMASDPDCLIEHFHFYPFGGFAKTAAYANAIAAGHIQLLPKGGFDVVGSA
A
>A0A080I937|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 1-250-04_S3_C2|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A136J7D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microdochium bolleyi|TrEMBL
MGFSNLRDRLDRMARALRPLFVNVTWGAGGSTATKSLELAEICQRELNLTTCLHLTCTNM
SRRTIDRALEDAKVLGIRNILALRGDPPRASEYRDANGNPENAIDEDFKWAVDLVRYIRK
THGDYFCIGVAAYPEGHADESHPLGQSLEHDLPYLVEKTQAGADFLMTQLFFDTDAYDHF
ERTLREHPSGTFKSIPIIPGLMPIQSYQMIKRTTKLSHAKVPAAIMDRLDEVKKDDEKVK
RLGVDILCEIIDRVNTIQGRTPGPKGFHFYTLNLEKAVSHIAERTDLIPPETAEDEEAVL
EEVVPPTIHVNGSTSQDNLLRVREQSRSRSRRQSTVGSDPRNRVIVSGGRTPSFPDYETS
QAEASIPAEAINTRANTLAISEGEGVLGREATWDDFPNGRWGDARSPAYGEIDGYGPTLH
VTRSQAIDLWGHPKSIEDINKLFVRHLQGSLKAIPWSEEDFNAETGTITELLIKLNSKGW
WTVASQPAVNGLRSSDPTFGWGPAHGFVFQKAFVEFFVPSAEWRVLLEKLQSAEVQGTVC
FFAANAAGDFISSDMTGGPGGETGLAAATQDGEASTNAVTWGVFPGKEIITPTIIEEMSF
RAWSEEAFGIFAEWAKVYPKGSDSDVFLERVRQDTWLVNIIHHAYVEKDALWELLL
>Q0C0E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas neptunium (strain ATCC 15444)|TrEMBL
MTRPAIPSQATKDPVRVSFEFFPPKSEAMNARLWETVQRLEPMAPAFVSVTYGAGGSTRE
RTHDTVRRIAAETALPPAAHLTCVSATKEEVLAVAEEYWQAGVKHIVALRGDPPAGMGAK
FEAHPGGFADSVDLIRGLREHRPELGKCFEISVSCYPELHPENLGWDAEIAFLKAKQDAG
ADRAITQFFFEPDVYLAFLEKARAGGVTMPIVPGIMLQPNFNGLKRIAGLCGSSIPAWLH
TLYDGLDEDEETRDLVTANVAADLCRKLQAEGVEDFHFYTLNRAGLALSTCRLLGLNPQS
AKAA
>A0A3D3F7K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium|TrEMBL
LLPPLKGNSIRQVFAVIDRLKEFDPKYINITTHHSESMYKEDAEGVYRKISVRKRPGSVA
IAAAIQNKYGIKAIPHIISQGFSKEETEYALIDLSFLGVTDLLLLRGDTKNLDALQRNLD
SHPHASGLQEQVNDFNRGVSFDGSSLTPPEIPFSYGMACYPEKHEESPNMESELFYTKMK
VQNGADYLVTQMFFDNRKYFEFVDRCRA
>A0A353RPF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium|TrEMBL
LKEFDPKYINITTHHSENEYKEDERGIFRKVNVRKRPGSVAIAAAIQNRYGIRAVPHIIS
QGFSKEETEYALIDLSFLGVTDLLLLRGDTKKLDAGQKSMDSHQHATGLQEQVNNFNKGI
AYDGSTLTPPEIPFTYGMACYPEKHEESPNMESEIYYTKMKVDQGADYLVTQMFFDNSKY
FDFVNRCRAAGITVPIIPGIKPIHMKNQLTVLPKVFRSDIPAELEKELRRCKDDEDAKEV
GVAWCISQCKELMQHKVPGIHFYALMATESVHKVASAIY
>A0A7C4X492|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MSAAVPPRGRFELALRSGRPVVTCEISSADGADPEDVRRRARLVRDYVDAVNVPDNTGGV
VHASPISSCAILVQEGIDPIMHMTVRDRNRLALQSDMLSASLLGIRNLLCLSGDHMIHGD
HPQAKPVFDIDSVQLVALASYLTREGRYLSGREIKPPPDLFPGAAENPFAPPYDFRPLRL
GKKIEAGARFIQTQIIFNVDRFEEFMGRVRDLGLDRKVPILAGVAPIRSVKAARYMRDGV
PGMEVPEALIRRMERAGDKKARREEEGIRICVEIIDRLRNMPGIAGFHLMPIQWESAVA
>A0A6B0DGF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MLLNVHYLVKYSLEITQDHIRKNHSNYLGGVEFITVPDNPFGKAGPGSVPMAYLLKERYG
KKTVATINTRDRNKVGIISEILAAIELELYGIFVVSGDKIKKGREVREIDVFQLISLIKK
YRYDYGSDIQIGATINPSRENELRIVRKKMENGADFFITQSIYNEDIILKNKWIRHLSVP
VYAGFMPLLSKKIITFYSKSFSIDEGMVKRLMDSYNLIEDNASLFIKIVKNTCDHVEGYH
IMPLGNEKFLEKISRVIKIC
>A0A6L6QD74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia eburnea|TrEMBL
MANHNFSIEFFPPKTPEGAEKLRAVRAKLSELHPKYFSVTFGAGGSTQQGTLDTVLEIMA
AGEQAAPHLSCIGGTRESIRAILQQYKSHGIKRLVALRGDLPSGYGMSGEFRYANELVEF
VRAETGDWFHIEVAAYPEVHPQARSPQDDMQAFVRKVNAGANAAITQYFYNADAYFHFVD
AAQKAGVNVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VSELCERLLAGGAPGLHFYSMNQSVATTALWNRLT
>A0A850REL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allochromatium humboldtianum|TrEMBL
MTTFTTPKRVYSVELFPPKTAEGMDKLKQEIPKINALGPAYFSVTYGAGGSTREGTFETV
AWLRSQGIDTAPHLACIGSTRDQVLEILAHYHEQGINRLVALRGDLPSGMGAGNSGDFRY
ANELVSFVRAEFGDAFTIEVAAYPEYHPQSGSPARDLENFKRKVEAGADAAITQYFYNAD
AYFGFVESCERAGIAIPIVPGIMPITNYTQLARFSDACGAEIPRWIRRRLEGYGDDVESI
RAFGHEVVLGLCRRLIEGGAPGLHFYTMNQSGPVTRLWRELGLSD
>A0A0F8WED8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lokiarchaeum sp. (strain GC14_75)|TrEMBL
MTENKVYSKLGELIAKGEFVLTGELEPEKTCDLTHTIQEAKEMAPYVVAANVTDSPLAIV
TINSMAAAHIIQRETGLECVWQLTVRDCNKIGIAGQIMGAQALGLHNVLSLTGDHTALGD
CPESKPVFDLDSATLIKLVREMVDTGSINGHEIEYPPKIHVGGAANPNSDPTEAEILKIG
RKAEAGVEFIQTQVVYDIDMTADFLREIRKYNVPVFLGIFPMKSYGIAKGFDMFVPGVDV
PKDILTRWKRVKTDVSDKKEQKETYDQLNYEFFKPFISELKSKGLLAGVHCMAVHYTRIF
PKLIDVIKG
>A0A6G2B8S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces taklimakanensis|TrEMBL
MALGTPSTRTDHAPTVRELLASGEHSYSFEFYAPKSERGERTLWNAIRRVEAVAPTFVSV
TYGAGGSSREGTVRATERIATETTLTPVAHLTAVDHSIAELRNVIGQYADAGIRNMFAVR
GDPPGDPTGEWTPHPQGITYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWESDIRHFVA
KCRAGADYAITQMFFYADDYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFAKLSNATF
PPDLAERILAVEHDPAAVRSLGIEYATELCARLMAEGVPGLHFITLNHSTATLEIYENLG
LHRRG
>A0A534N047|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MAEAVGVRTVRSGSHLERMLASGIFAVTAEIAPPASADPTDIREIVSRYRGAVDACNVTD
CTRARVRLSSLAAATIALREGIEPVMQMVARDRNRIALQADLLGAAALGIRNVLCLWGDP
VSAGNEPEAKGVFDLKTEEMIETFRDLRDRGRLRGGDTVDAPPKVFIGAAADPFRGSKEE
SFAKLRAKVLAGADFVQTQAVYDIDAFEEWMRLVRKEWLHEKVYILAGVIPLRSAKMARF
LVETLGATVPKHIMDRMEKAPDPKAEGVSIAVRTVKALRKIDGIRGVHLMPVGRDGVVAR
VVKEAGLLPRPEPSF
>A0A2E0K4H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MRIRDKIKKPQXPVVAYEILPPREEDGTLNSYAETISSLLSQTHIDAINIPEVHDEVGRG
DRPVANQKRGEPREFGMLLQDIVGIEAIINRVVVHEPYDKQMQWFEETNTKFEIENMIIV
GGESSKVSYPGPSVNKILEAITNKHNQNGGNIFCGGIAIPSRKQESKNLINKSNNGSEFF
TTQVLYDSENIIKMINNYQTRCNELNTFPRRILLSFAPVSSQKNVEFLKWLGVEIPTNTE
HYLQARPGSMTERSLDVAIEVLNEILNHIEKNDLKVPVGLNVEHIMSYNFQSSVEMLQEL
ARIYREFCIKAQQYS
>A0A482IJH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus metallidurans|TrEMBL
MTDRYFSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSTRDSIRQILQTYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQARSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRAMGVEVPIVPGIMPITNHSQLMRFSEMCGAEVPRWVAKRLESFGDDKEAIRAFGLDV
VTDLCTRLLDAGVPGLHFYTLNAAGATKAIWQRLKL
>D2HKB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ailuropoda melanoleuca|TrEMBL
MDHPTPKVLPARPRGPSLGMWALEAGRVRFSVPPSISRNRAMVNEPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERHDRLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQITG
YLHKARRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFQFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQQLLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFAHYLS
GEPNQQGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPAPERETEA
>A0A429BE29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC 01325|TrEMBL
MALGTASIRQDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGDWVCHPQGLTYAAELVELIKASGDFCVGVAAFPAMHPRSVDWDADVRHFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAAGCDTPIIPEIMPIASAKTLERIPSLTNAGF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEEVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>J4YIA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter marplatensis|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGATRQDLRDILQAYKHEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQASNPSADLDHFVAKVKAGADSAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPLAVWKELSL
>A0A4Q1CT56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. MA5|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYTPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDLRYAAELIAFI
RAEHGNAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVDVPITPGIMPIANFSQLRRFSEQCGAEIPRWIGRKMQAYGDDAASVRAFGAEVV
AKLCQRLIEGGAPGLHFYTLNLAKPTTAVLKLLQG
>A0A0Q8A8S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Root166|TrEMBL
MSIDLSAPPLPFSFEVYPPRSDARVPALHETIRRLAASGPRFISVTYGAGGSTGGRSLEL
LSHILRTTDVEPLAHLTCVGSTFAAANALVREFLDAGITSFLALRGDPPAGVSEDDMFLG
DLESAAQLVQLIDRVQAERAPYSEYAIPGVPGAARVAPRTKVDIAVAAFPNGHPRSRHPR
EHIDALLAKQAAGATLAISQLFFHADDYLAFVQRSREAGVTIPILPGIMPITSPARLRRT
LELSGEELPAELAISLEIEPTAEGQRAVGVAHAAQLAREVVDGGAPGVHLYAFNSHDTVL
AVLRDAGILTTPLEKESAS
>D7CEV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces bingchenggensis (strain BCW-1)|TrEMBL
MRDLLASGEQSYSFEFFAPKTEKGEQTLWNAIRRLEAVSPTFVSVTYGAGGSSREGTVRV
TERIATDTTLTPVAHLTAVNHSRAELRNIIGQYAGAGIRNMLALRGDPPGDPMGEWVRHA
DGVTYAAELVELIKESGDFCVGVAAFPEMHPRSADWDTDVRHFVDKCRAGADFAITQMFF
YAEDYLRLRDRVAATGCTTPIIPEIMPVTNVKQIERFAQLSNAAFPPELAERILAVKDDA
AAVRSIGIDYATELCARLMAEEIPGLHFITLNHSPATLEIYENLGLHQRS
>A0A560RF49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SJZ080|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A158CVW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia temeraria|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRASRAELKKLSPKFVSVTFGAGGSTQQGTLDTVLEMAS
EGFEAAPHLSCIGSSKDNLRAILSQYRGHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQEHGDWFNIEVAAYPEFHPQSRSPKADLENFARKVKAGANSAITQYFFNADSYFKFVE
EARKLGVDVPIVPGIMPITNFTQLMRFSDMCGAEVPKWIARRLESFGDDRESIRAFGVDV
VTSLCRRLIDEGAPGLHFYTLNGSWASKTVCERLGFKSV
>A0A1V9IR40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sporogenes|TrEMBL
MHIKELFNEKNLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELEENNIENILALRGDMPNDKNIIGE
YNYAFELIEKIKENNNFGVSGACYPEGHIECESLKQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLSKTQQKNINVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>K6U5S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. Maddingley MBC34-26|TrEMBL
MIKEYLQNNILISDGAMGTYYSELTGNDVSYCEFGNLNHKDIIRKIHSDYIKAGANLIRT
NTFSANTYDLGVSLDRLKDIIKSGIEIAKDAATDTSVFIGASIGPIKEDNLDESHDDILA
EYKFIADCFLEDGIKIFIFETFSNYNYLKEISEYIKSKDKDSFILTQFAVKPDGFTRDGL
SVSKLIKEVKKVEHIDAYGFNCGSGPTYISEIIKKINIGGDIVSALPNAGYPEIIHERTV
YPNNPIYFAKKVSEFKSLGVSIIGGCCGTNPNYIKELSALIHENSKKVNTTIKNQEQTKE
YKKKTENTFKNKLDNNEFVVAIELSAPIDTDISKLIAGAKICKENNIDLVTVPDSPMSKV
RADSTIIAAKIKREIGIEAMPHVCCRDKNTNAIRSSLIASHIENIRNILAITGDPISDAS
KVETKSVFNLNSFRLMELINDMNEEFFKEENLLIGGALNLNVRNKEVEYNRMLKKIDKGA
KFFLTQPIYDDEAIEFLKKIKERTNIKILAGLLPVVSYRNAIFLNNELPGVTIPEKYVNM
FTENMNKEEAQEVGVKIAAEIGKKLKGISDGLYFITPFNRVNMLMEIIKQIKE
>A0A7X5P791|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sporogenes|TrEMBL
MHIKELFNQKNLVFSFEIFPPKVTSSIETIYETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTREDIDSIINELKENNIENILALRGDILKGKNIIGE
YNYAFELIRKIKENNNFGIAGACYPEGHIECESLEKDIKELKRKVDAGAEHLISQLFFDN
NTFYEFLNRTEQKNIKVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKEA
IRDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARRITESTKSIFNSINKDVAV
>A0A1G0WJT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_38_69|TrEMBL
MENTFEKRLQESVLIFDGGMGTEIYKKNFFINTCFEELNLSAPKIISEIHKDYAKAGAEV
LTTNTFGANRNKLSKFGFANKVAEINKAGVKLARESAESNIIVAGSAGPIGEIPYNSGVT
STNIIDMLVEQLIALKEGGADFIMFETLPSLRDVQQSIDAIRQVKDIPYVLSMTVNRFGE
TDKGECLSTLLAPLAKMDYKPTAIGINCGLGPEALLSVVEKLSKICSYPIIAQPNAGSPR
SVDNRTIYMTSPEYFTTYVLKYVALGVRGVGGCCGTTPDHIKDLARSVKPTSKNAFAKTI
NLSISEEHLQSPVPTSQKSKLGAKIAAKEWIKTVEIVPPKGYNLKDVINKAKFCKESGVD
AINIPDGPRASSRMSPIITALMIQQQAGIETILHVCCRDRNLIGMQSDLLGCAAAGVNNL
LIITGDPPKLGNYPYASAVFDADSIGMTRIQSNLNRGVDIGGNTIGEKTAALIGVGADPN
AIDMEREFRRTVEKIEAGAEFIITQPVFDVNSLISFYKKIEKFKIPLIAGIWPLASYRNA
EFMKNEVPGVVVPDSIMKRMARYESREDQRAEGISISRESIELIKSFVAGVQVSAPLGNV
ETSLKVLK
>A0A6P1F584|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. VKM Ac-2759|TrEMBL
MTRARFEIIPTDDIGERAARAFPDPSTVTLTVTSLPKHGTERTVESALALASRGFRVVPH
LAARNLGGRSDLERTLGRLGDAGIDEAFVISGDATSAVGAYSTSLELIRDAVEIAPGLAL
DIAGYPEGHPHLSDESIERHLLERAPFIRSIVTQMCFDVDAVVRYADGLRSRGITAGVWA
GVPGPVERARLLSLGARIGVGSSLGFLKRSSSVAGGLLRGRRFDPAAFVGRLEAAAGDRL
EGLHVYTFNELDGLGAFGG
>A0A2R7MY75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. HMWF021|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A1V5QUH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium ADurb.Bin341|TrEMBL
MIPTEISVEFFPPQSPAGFEKLRAERAKLAVLKPAFFSVTYGAGGSTRERTFDVIQEIAA
EGHNAAPHLSCVGSSRADIRDILQRYQDKGIKRIVALRGDLPSGMAEAGELRHANELVEF
IRHETGDWFRIEVAAYPEWHPQAKSPKDDLEAFARKVRAGADSAITQYFYNPDAYFHFVD
HARALGVDVPIFPGIMPIISFAKLARFSEVSGTEIPRWMRRKFESFYDDTDSIRAFGLEV
VTELCERLLGGGAPGLHFYSMNQSALTLEICRRLGVLPGQA
>A0A657FWW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Denver|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2P8EAK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cecembia rubra|TrEMBL
MKITEYINQAEKPLFSFEILPPLKGQSLKDLCEGIEPLMEFNPPFVDVTYHREEFIYKKH
PSGLLEKVSTKKRPGTVGICAAIMNRFKVEAVPHLLCGGFTKEETENALIDLNFIGVQNI
LALRGDAPKSENKFTPEPNGHAYTKDLVKQIVNMNHGRYLHEETETGFHTDFCVGVAGYP
EKHFEAPSLKFDLKYLKEKIDAGAEYIVTQMFFDNQKYFDFVKKVREMGITVPIIPGIKP
ITTLGQITMLPRTFFLDLPDALMDELEKCKTNADVKEVGVDWAIHQSKELIANGVPVLHY
YTMSKAEATYRIAKEVF
>A0A1W9X292|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beggiatoa sp. 4572_84|TrEMBL
MTSQIPALTISCEFFPPRTEKGVLKLRQTREQLQALQPAYFSVTFGAGGSTQEKTFETVV
EIQEQSDFDAAPHLSCIGSSGENVLKLLQNYQAHGIRRIVALRGDKPSGWAGPLGDFRYA
NELVEFIRTETGSHFHIEVAAYPEFHPEARSAKADLDFFKQKVDAGANSAITQYFYNAEA
YFRLLDSCAERGIDIPIVPGIMPIGNYEQLVRFSDTCGAEVPRWLRRRLADFAEDKEGLQ
AFGINVVTKLCERLLEGGAPGLHFYTLNQAGPTLEITKRLGLFSLS
>A0A344UL47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium phragmitis|TrEMBL
MTQTPRTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGQAAAPHLSCIGSTRENIAAILNEYRANGIRHLVALRGDIPSGMVAAGEFRYANELV
AFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLANFVRKVQAGADSAMTQYFFNADSYFRF
VDEVRARGVDIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRLRMQAYYDDAASIRALGL
DVVTELCDRLLQGGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A0U2XG01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MTRLTTSLAGTQPNEDGSSLASEKPLMGNISIELLPEHVATFHPTAANLKPGSFVFLTHI
GGKSLAAQAGAAARIKAMGYEPVCHLGARNFTSRDEYANHLSALSDAGVTTVLMIGGNSS
DSVPPMHSAMELLSHSIVPRTGIKRIFFAGHPEGHPSIPPEILVPTLLEKINVARELSLV
PEIVTQFAFDGAAMAAWGAGLRKAGIDVPIRFGVAGVTSLPKLIKFAMLCGVGASLKGLS
RQGGSILKAMRDQDPGDVISQLRIGTEAYALKGIDLHFFPFGGWEKTLNWIAASSGAH
>A0A2X3KIH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MTYGANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVAL
RGDLPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGA
NRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQ
MFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2X3KM99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFSRRVPVKWSRPCGTPSIALAA
>I4FN69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa PCC 9717|TrEMBL
MTTRLQRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQIACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A7C3XSG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Caldatribacterium sp|TrEMBL
RNRIALQSDFLGACALGIENFLCLTGDHQSMGNHPQAKNVFDIDSVQLLGILNDMKEKKI
FQCGETLKGEVKAFLGAGENPFADPIEFRVYRLAKKVSAGARFVQTQAVFDVEMFARFME
EVRKMGLHEKTHILAGVIPVKSPQALRYMQNEVPGLSIPASLLERMEKAPDPREEGVQIC
VEIIEKLKTIEGVRGVHIMAIAWESIVPEIVQRSNLYPRPRKEVG
>A0A177S9N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MNSLKQALRDRQFVCVMEFVPKPQRFAAFEQLMQRGHLCGWPMFAGIADRVGSNLDLSPL
DTFAALSTPVPVMPHFSGKDRERQDLLAQLERMDRLGLDQLLLLTGDRLHGHEPGQRPVR
YLESVAALGIVRRARPDWLLGAALNPFKYCEEEGGAQYFKAQKKLAAGADFLILQLGFDM
ARYRDAMDWMQRQPTPRPMLACIMGLTHGRAKMLEHVAGVTVSPSMLALVAAEEAVSKAH
AQARSVDRLALQIIGLQRMGYAGINLSGVHDIAQLLALEQALDAWREKIRTDEEWALAWA
RSWEMPGVPAVTFNPPESDWKAGESRVSATPKEKLRYHLLSTLHSTLFNRTTLLSRAFAW
TVRRPLWSTQAGQRWLHRLERGVKRPLVGCDTCGSCRLEDTLYICPETCPKGLANGPCGG
TRLNRCEFGDRECIHSIKYRTAKSVGQTAVLTQRLIPCVEVGGRQRSSWPGWFEADEKSS
SDRIGDTAVS
>A0A059V5D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSTERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSCQATPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFALARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPMWATRLGAQVLHKVEHAVKHPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTALLTERLIPCIELETRHRSSWPQWFQAQTP
RQLSPQPAPRTQPES
>A0A7W7IG30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura catellatispora|TrEMBL
MRRLRPDRPPTVRELLASGGRSFSFEFFPPKTDKGALNLWRAVRELESLQPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPDGVEYAADLVRMIRSYGDFCVGVAAFPYKHPRSPDIESDTRYFIEKCRA
GADYAITQMFFRAEDYFRLRDRVQASGCDVPILPGIMPVTQMSTIERSEQLSGAPFPPEV
RARFETVADDPEAVRRLGIEHAAELCRELLEQDAPGIHFITFNKSTATREVYGLLDAASY
GGRGSAPPMTA
>A0A059V2N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A6S5TN50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMAVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKEELRALIAQYKAAGIKRIVALRGDLPSGMGMAYGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQARNFESDLTNFVHKVKAGANSAITQYFFNAESYFY
FVERVQKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A6N7QUA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spiribacter sp. C176|TrEMBL
MKTLLEAVPPELHRGPAAVDAVVAHVAAVHADFPLDGVNIPEIHEEPSRSSKGERHKPFA
PRMAPRELAYVIQEQLGVPCMINRVVVTTPADQLVDWANETWERYGINQFVLVGGGLSNQ
AYVGPSVTQANQLLREHAAIDALRIGNICIPSRDGEVARLQAKTDAGADFFTTQILYEAD
DLQAVLTGLDETSGPTPDDLWVALCPARTLRNIRFLLWLGVNIPDALEAWLIEAPDEVLE
RSLAQIKRVWQSLSQDRAARIRPALGINLAPIGAIPTDVTVGLAKELAAI
>A0A126SB98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTTLDANAFACILEFVPKPGAERFATLETLMARTRLCGWPLTVAIGDRVSSALDMS
PLEAFGSLANPVPALLHFSGKDRERRDLLAQLQRMDAAGLDQLLLLTGDRLPGHTPGERP
VRYLESVAALQIVRQARPHWLLAAALNPFKYQEAEGGAQYCKAEKKLAAGADLFILQLGF
DIDKHQEAFDWMQRQPRPKPLMACIMALTEGRAGMLDHVAGVTVTPSMRALLAAETAVSK
AYARERANHRLALQVIGLKLMGYAGVHLSGIHEVAQFEALEQAIGALQPQFTSLQDWAPA
WEAAWQEADLAPVTFHSPGHAWRLGQRQITASNKERARYHLLSAMHHQLFSRTTALSKGF
GWAVTRSLWANPTAAQWLHRLERRIKRPLVGCDTCGSCRLEDTLYICPETCPKGLANGPC
GGTSLDRCEFGDRECVHSAKYRLAVSVGRTEVLRERLIPCVQVESRHRSSWPVWFEPAPL
AIAEPTPMSADDLLAKTRERLAAPQRVKVSLDDL
>A0A7W2KWR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMAVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEAKVPAAPHLSCVGDTKEELRALLAQYQAAGIRRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFETDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYNKLARFSDACGAEIPRWIRKQLEAYADDAASIQAFG
EEVISHMCEQLLQGGAPGLHFYTLNQAEASLAIWNNLKLPR
>A0A846R2W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora profundi|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTEAGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPEGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSVDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PTALAERFERVADDPEAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLK
VGARV
>A0A848G3V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zoogloea dura|TrEMBL
MNKPPISIEFFPPQTSEGVEKLRVTRARLAELKPEFFSVTFGAGGSTQARTFETVFETQR
EGYEAAPHLSCIGSTREHVREILKRYQDAGIHRIVALRGDLPSGVGDPGELRYANELVEF
IRAETGKHFHIEVAAYPEYHPQARSPKDDLLAFKRKVDAGADSAITQYFYNLDAYLHFRD
ECAALGVNVPIVPGIMPIVSFSKLARFSDACGAEIPRWMRRKFESFGDDSESIKAFGLDV
VGELCARLIEAGAPGLHFYSMNQAGPTLALCERLGRQG
>A0A5P1R4A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVQVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRTETGDHFHLEVAAYPEMHPQARNFEADLGNFVQKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLALWNNLKLPR
>A0A1V9A7H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora piscinae|TrEMBL
MRRVADRLNGSDRPTFSVEFFPPRDEADEAILWRSIRELEPLDPAYMSITYGAGGTSREG
TIRNIARVATDTTLVPMAHLTAVNHSVAELRNVIGHFAAVGVHNVLALRGDPPGDPMGEW
VAHPEGLHYAEELVRLTRELGDFCVGVSAFPYGHPRSPDLETDTHYLVRKLRAGADFAIA
QLFFEADDFLRLRDRVAAAGCDALMLPGIMPLTTPKTLRKTIELSGATPPAWLTERLDPL
SDDPKAFRAEGLNVITELCERLLREGVPELHFYTFNRSKATRELVDRLGLRSPRAEPALT
TRP
>A0A1V1W1J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. PD653|TrEMBL
MANERTRSIGDLIRHGERSFSFEFFPPKDDAGEEQLWQAIRELEPYRPTFVSVTYGAGGS
TRDTTVRVTGRIAAETSLTPMGHLTCVGHTRAELRSILASYADAGVANVLALRGDPPDGP
GTPWTATEGGFTYADELVALVKQTGGFSVGVAAFPEGHREAASLDHDVQVLLGKQRAGAE
FAITEMFFRASDYFGLVERGRAAGVDIPIVPGIMPILNLRQVTRMAELSGRAVPAEVLDR
LSAHEDDPAALRAEGIRVAAELCDELLGGDAPGLHFYTLNRSKATREIFAALNMAV
>A0A3R9DNK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMAVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALIAEYKAAGIKRIVALRGDLPSGMGMASGELRHASDL
VEFIRQETGDHFHLEVAAYPEMHPQAHNFEDDLANFVHKVKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDAASIQAFG
EDVISKMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3C0IF77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microscillaceae bacterium|TrEMBL
MKITDIFEKQVKTFSFEFFPPKTYTATIELGINIGQLMKLDPSFVSVTYGAGGSTQSASF
DLVDYIQNKIGWTTMAHYTCVGASRSKIEADMDLLYEKNIRNLMLLRGDPPKGETNFVHN
PEGFNNGSDLVAHISQQKRFCIGAGAYPEGHVESPDLATDLHFVKKKVEAGADFLVTQMF
FDNAFYFQYVNQLRQMGVNCRIIPGLIPITNFGQIKRFAELSAAKIPEATIERLAPYQKD
EKKMYQIGVDLAIQQCEDLLRNGAPGIHFYTLNKSTATVDIFESLPKTLKDIYTVTYH
>A0A1S7LIP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetococcus massalia (strain MO-1)|TrEMBL
MNSNSRLSVELIPRDQGELEADLKRVAAAFPQVTTINIPDLVRYPIRSWDGCVMAKAHFS
HAVPHIRAMDMPRDGSLPMLEVLDKHGIDEVLIVSGDVPEEGQERPEPSALEVIKRFKKL
APHIKVYGALDPYRSSILDELEYLQEKRDAGMDGLFTQPFFDLRLMQIYADQLQGCNLFW
GLSPVTTERSMAYWQRVNRVVFPASFKPDLAWNIDFARDAMALAEDLGQHLYFMPIRVPV
ESYLEGVFAS
>A0A0F2QTZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatitalea sp. BRH_c12|TrEMBL
MSLQKRLASGEFVVMAEMNTPKGVDISQLITNARKIKGRVDAVIVPDMDNGVMRMSALAG
GVLMQQQGIEAVIHLYGRDRNRMALQGDILAAHVLGIQNVVVVHSEDMANGDHRDAKTVD
DLDELGLIETLATLQKGKDLAGFDLEGAPSFTTGCTVASYADDDQMAAELEKARKKVQAG
AQFIVAPPVFDVDRFGVFLAQAKGLGVPVIATIFLIKSVGIARYMALNEPGAHISEDLIR
RIRKASDREAECLRIAGETIAALKGKVAGVKIETNGWEHRLASILDYAGV
>C9L8P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia hansenii DSM 20583|TrEMBL
MRRYKLMKLSDAMREKMLLSFELFPPKTDKGMENLPGTIEHLCKYKPEYISCTYGAGGTN
VGKNMDVCKMIKDAGTIPVTHFTCIGNTAEGIKDQLQNYLDNGVDHMLALRGDLPFGWTG
TGGDFAYATDLVAYVRKEFGDKIEIAVAGSPEGHISCRSLEADIAVLKQKQDNGADYIMT
QLCWDMEQFKYWLDAIRCAGITMPVDVGIMPILDQAATINMALSRNACVMPRELCEIISK
NWIFPNPFVQDPFDADVEGKKARFKEAGIEYTIRQIDEYRACGIDGIHLYALNKWKDVSE
IIDRSGLRTLV
>A0A0V8QCM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetivibrio ethanolgignens|TrEMBL
MIKNLYQKKKPVISLEVFPPKEDTDISLIYNTLDKMKELSPDFISVTYGANGSSRHRTVE
IAAYIQNTLGCEALAHLTCAALDEAVLLDYLSQLKEANVKNVLALRGDMPKDMTRAEFEG
RHFRYAKNLINAIPKHPLGSIGAACYPEIHPESLDQADDIAHLKEKVDAGADFLITQLFF
DNFIFYDFMEQLERAGIKVPVSAGIMPITSISQIQRIVRLSGSQVPSSLAHILAKYQDNP
EDVKKAGLEFASIQIDGLIQNNAAGIHLYTMNKFETADMVFRHIRP
>V9FHK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora parasitica P1569|TrEMBL
MKVIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMAEADIKKALDEAKDAGIQNILALRGDPVRGASS
FDECDRGFSHAVDLVRYIREKYGNHFCIGVAGYPEGHVEIKDKKADIQYLKEKVDAGADF
VITQLFYDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTSFCNTFVPDEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRASESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSNTSTPRERRAMWGEAPAAKEDVRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGALSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
PSIQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEPGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSPATSP
>A0A5W8C9E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Colindale|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>I9UDV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus CL09T03C04|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A2P1VED9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. PMC12|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQLLYARKPQFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
ARRLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVV
TDLCARLAEGGAPAMHFYTMNQSAATLALLERLD
>A0A0F2R0J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatitalea sp. BRH_c12|TrEMBL
MSENGYKSGSNLEKVLKAGHFAFTGECGPPKGANVAHLKEKMEPLRGMVDAINVTDNQTA
VVRMSSKAASCLMVQAGLEPNFQMVCRDRNRIAMQSDILGASALGIRNMLCLSGDHQSFG
NHPESKNVFDIDSMQLIALVKKMRDEGRFLNDEEIDEPPKLFIGAASNPFGDPVDFRVYR
LANKIDAGADFIQTQCIYNMPRFREFIKRAVDMGLTEKTYILAGVTPMKSAGMAKYMARS
VPGMDVPADLIKRIEGAGKGKMAEEGIKFAIEQIQEFKEMKGVAGVHLMAIEWEHKVPEI
AERAGMLPRPKVD
>A0A8C4HCN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dicentrarchus labrax|TrEMBL
MVNQVQRGDGSWQSSKSDSSGASNSGGESSKDSSRCSTPVLDADRSDRLRDKMRKRMESG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAI
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEGDLRHLKDKVDAGADFVITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIQQAVDMCRLLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLQMWGEELINEESVYEVFTCYITAQPNSRGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVDVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVADPVSFMYWKVRWRPECCHGSP
INPVEFLRLQNQCHGAAELFWWPKTLLRLWLPPNSGVNY
>A0A7W7LLB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces olivoverticillatus|TrEMBL
MSDPSFSFEFFPPKTDEGERVLWDAIRRIEAVAPSFVSVTYGAGGSSRDRTIDVTRRIAR
ETTLRPVAHLTAVGHSVAELRQIIGAYADAGIRDVLALRGDPPGNPRGPWTPHPQGLTYA
AELVRLVRDMGAFTVGVAAFPERHPRSRGWDDDIRHFVAKCRAGADYAVTQMFFHAEDYL
RLRDRVAAAGCDIPIIPEIMPATDVRQIRRFAELSNARFPDDLARRLETAREDPAAAHRI
GVDHASALALQLLDEGAPGLHYITLNRSTATLDIHRNVLGSRLLPRSPGRFTNETFATSR
R
>A0A1T3CG36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma guizhouense|TrEMBL
MDKITEKIAALPPDGEYFSLEFFPPKTAMGFSNLRVRLQRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREIGLTTCLHLTCTNMSQVLIDQALEDARALGIRNILALRGDPPRAEY
RDADEPDQASSEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPY
LVEKVQAGADFIMTQLFFDIEAYEKFETTLRNHSSGAFKTIPILPGLMPIQSYAMIKRTA
KLSHAKIPEETMARLNAVKGDDEKVKMVGVDIVSELIGQIREIKSRTPGPKGFHFYTLNL
EKSISFILERTKLIPDAAEDEEAVVDETVAAAAQLVVPKISVNGNVPPRSSSHARTGRRQ
SSVGSDPHNRVIVGRAATHPEWEATSTEAGVPAESVNTRANTLAISEGEGALGREATWDD
FPNGRFGDARSPAYGEIDGYGVSIHMSVTQAVRLWGHPKVASDINDIFVRHIRGEISAIP
WSEEDLLPESSIIKSKLEAMNRKGWWTVASQPAVNGLPSTDSTFGWGPSSGFVFQKSFVE
FFIPSADWKILYDKLTSAEVEEVVCFYASNAKGDFISSDASGGSGRAVMSASTNAVTWGV
FPGKEIVTPTIIEEVSFRAWSEEAFDIWAEWAKVYGRGSDSQKLLDEIKEDRWLVNIIHH
DYVDTEALWRLLIE
>A0A5B9QNI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseimaritima ulvae|TrEMBL
MKLADYYRDGRRGLSFELFPPKTEAGLQSLYEHVDRLMAFKPDYFTCTYGAGGSTQGLTL
DVLSEVRRRTELPVASHLTCVGATADEIRTYLQEASQRGTDFIVALRGDPPKGETTFQAV
AGGLRYANELVELIRTQPHPFGIAVAGYPEVHQEALDADSDLSNLKRKVDAGADIVITQL
FYDNADFYRFRERCEQNGITVPIVPGLLPITNLAQAQRITSMCKAKLPPQLVQRLSEKEA
PDWQFEIGVQHAREQLLDLLKNDAAGMHLYVLNKSQAAEKMLEGCQLGSTA
>A0A2S1IB53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces nigra|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVRPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGDWVPHPRGLTYAAELVELIKASGDFCVGVAAFPAMHPRSADRETDVRHFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAVGCDTPIIPEIMPIASVRTLERIPSLTNAAF
PDALRERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHPPQA
>A0A5N6VHU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus transmontanensis|TrEMBL
MFPFPLIGGPSSLFNYHLSRNFAGTDSGIKMEKITDKIAALPPDANYFSLEFFPPKTQMG
FANLQARLERMAQALRPLFVTVTWGAGGTTAQRSLELAEICQRQLQLTTCLHLTCTNMSR
ALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNRDFTFAVDLVRYIRQKHGDY
FCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTQAGADFIMTQLTYDIEAYTRFENMLR
THESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVQIPPQILSKLEEVKHDDDSVKRIGVD
IISSLVDGMRDIPCPGLRGFHFYTLNLEKTVSFILERCDLIPPYSEDFDAIEEGGDISAM
DGAQLRSLTRRRASSINSLPHNRVIVDKLHASEVSSKASVSHEAPATSAGMPAMPPDRST
TLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVPPAVAHRIWGFPVSH
EDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELLQLIDGNGWWTLASQPA
VNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLLQKHGHEKLAWFAANIK
GDFESSLPAQTSDADPIEMNPDNVNCVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWD
EWRRIYPRNSATERFLNDVKDDVWLVCVVGQEFGAGTEMGSEEEEDEKKFMWRVLLNAKK
>A0A2T0AU70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorella humiferrea|TrEMBL
MKTESKLERLLSQGHFVVSGEIGPPKHANPEGIKKHAALLKDYVDAMNLTDNQTAIVRLS
SIAAGVHVLASGGEPIIQMTVRDRNRIALQSDLLGAYSLGMRNVLCLSGDHQSFGNHPTA
KNVHDIDSIQLIKIVKDLRDEKKFACGEELKGNEPRFFIGAAANPFADPFEFRVLRLEKK
INAGADFIQTQCIFDMERFEKFMAMVRERGLHKRAYIIAGVMPLKSAKAARYMQQSVAGM
IVPEEIVSRMEKAADPKAEGVAICVEQIKHLRNIEGVAGVHIMAVMWEDIIPTIVKEAGL
YPRPKVD
>A0A0R2F3E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus camelliae DSM 22697 = JCM 13995|TrEMBL
MKVNRLFKDHQVLSFELFPPRRRSPEEDYRRIDDTISAVSELNPDFVSVTLHTGKKDQRH
VTLDLADRIQKKYGLPAVAHLPAVQLTTAEVDSLLEDFKAAGIENILALRGDIPNGGRVA
NDFPHASDLITHIHEYGDFNVVAACYPETHPEATSPEADLQHLKEKVDAGASQLISQLFF
DNHVFYDFVDRARAAGITVPIEAGIMPVLSQHQIDTMALTCGVSLPEKFLSMMKHYEGRP
DALRDAGIAYAIDQIVDLMVHGVDGIHLYTMDNPTVAKRIVEATRSLVRQ
>Q0P954|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALADIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A7W4ALM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. SG45-6|TrEMBL
MALSLKEKIEDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQARPFAFKQTVDPREYSHLLRNLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDL
QNVVLVGSPSSVGDIKLSLPDAYKALAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCKFFISQAVYDAQATIELITSYARTCKAQGITPQRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKLIA
>A0A0P7JS40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MREQTFSVEIEANPTDLIQMKHYLHKWQPDFVSISNLSRYSYEEMVQCARYIQTDLHIPV
VIHLTGLTHTKEQIKEAFKELMELKIRNFLLVRGNIHHNMHIEDDFNYASDLIKYVNQLD
EDSKINVIAACYPDIHVLADSLTEDIEYLKEKVNAGVDSLISLMCFDNDRIYKFLEKTRE
YGINVPIRIGIMPITNPFKRHYLAHNDVKMPEFFEKTDDLLDEGIDFAVNQINDLYEHHV
NGVHLYTHNDWIVSDRVFENIKHNL
>A0A0J5PUW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus fumigatus Z5|TrEMBL
MEKITDKIAALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSEE
YNTHGEDDSNKDFTFAVDLVRYIRKMYGDYFCLGVAAYPEGHPVDSYQDVQDPVRDLPYL
VEKTLAGADFIMTQLTYDIDAYTKFEQMLRNHESGAFKTIPIIPGLMPIHSYKILTRTTK
LSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLNLEKT
VSFIIERCGLIPDYPEDSGAVVDDDYTTAPTGAQHRSLSRRRASSVNSLPHNRVIVDRLQ
VPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQISEGQGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVSGAVARRIWGYPVSREDISALFRRHVSGDLYIVPWSEGGAEENSS
GLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFF
CPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWG
VFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRVYPRGTPTERLLEEVKNDVWLVCVVG
QDFGAGTENGSEEEQQETKWMWNVLINSQ
>A0A0M9D6U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MSLKDTFKNKTVFSLEVYPPKTPEGTKKLVNALTGIKRIKPDFISITLGAGGSQNNNALE
LSSMIQNDLNIPAMAHIPGIYRSKKDVADFLKQLKQHNINNVLALRGDINPDETPVGDFN
HASELAEFIKTQGNFDITGACYPQKHPESIDLVDDTLHLKKKVDNGVGHLITQMVFDNQA
FYDFRQRLKLAGINVPVEVGIMPCTNCNQIKHITELSGLEMPRKFVDIMNKYANNKEAMR
DAGIAYAVDQIVDLVANGVDGIHLYTMNNTYVAKKIWEATHSLFEATSYQLQHPSLSGSD
NQ
>A0A3S1KD31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1E.F.Ca.ET.063.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDDMEARLWDTVTRLEPLKPQFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIREFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYAN
>A0A285JES3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rheinheimera tuosuensis|TrEMBL
MAFANAQYLDAINRNLHDVQGKVNVSFEFFPPRTAQMEQTLWQSIERLAPLTPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASKQQLTDIARDYWNNGIRHIVALRGD
LPPGSSDVPELYAADLVEILRSVADFDISVAAYPEVHPQAPNAQFDLLNLKRKVEAGASR
AITQFFFDIEKFLRYRDRCAAIGIDVDIIPGILPVTNFQQLQKFAGLTNVAIPDWMNKAY
QGLDNDPTTRNLVGANIAMEMVKVLSREGVDQFHFYTLNRSELSYAICHLLGVRPVL
>E4HI90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium modestum HL044PA1|TrEMBL
METSPQAGHVARLLGAPPSLSHMQSQTPTIADLLASGERPLHSFEFMPPRSEDDVYRLWS
ATDALVPMAPDFISVTYGANGSRRDRTLRCTQHMVSTGLRTVGHLTCVAQSVADLEQMVA
DYAESGVDHVLAIRGDMPGGAGLPWVPHPEGLPNATELVRLVKRIHPEACIGVGAFPDGH
PEARDIDLDARILVDKAQAGASFAITQLFFLPSHYQRLVERVRGMGCDIPITPGIMPITS
YGQIRRFSELAGTDVPAELVAQLEEAKGDKAAVRRIGLAAAVDMCCELLDAGAPGLHYYT
LNRSRATTELRTMLAQRRPELAGLPREFEVSSAV
>A0A518VGC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium carotovorum subsp. carotovorum|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWESGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>X6F535|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNHC229A00|TrEMBL
MTGRQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDDITETQVDMVK
TAH
>A0A737VAI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Sendai|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A562HJM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfitobacterium sp. LBE|TrEMBL
MENRFKQSLLDPNTLSVTWELVPGRGAREKAQESALLAAEQAAKGGKVHALTITDNPGGN
PAILADYLGQEILKLGIEPLVHFTCKDKNRNQMESQLYALDRAEVRSLLVMTGDYTVSGF
KGRPKPVFDLDPTHTLELIAQMNEGLGIPGPKGMSYHQPSDFFAGAAVSPFKGTEAEQMV
QYYKLKKKVASGAQFIVTQLGYDARKIHEVLQFMKLNDLNVPLVGNIYILPFGAAKIMNQ
NQLPGCVVTDKLLAEIDKERTAEDKGVSARLLRAAKMYALMKGMGFAGVHIGGHNIKYEQ
VEYVIEKGEELSKDWLALVPEFDYPMPNGFYYYEKDPKTGLNTTTPVNRKNLPLDAPVGV
AYSGMRLMHSMLFTPGKNFFPVMRKIYKGRKDNRKHGLEHLAKVITNDCKDCGDCAMFEL
AYLCPMSQCPKNQRNGACGGSYQGWCEVYPNQKQCIYVRAYARLKKYDEEGDLDSHHIPP
ANWDLYQTSSWSNFFLGRDHSGKILGIPTPEEEAAKAKGADPAK
>A0A6G1GPC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aulographum hederae CBS 113979|TrEMBL
MHISEKLANAKEAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHSFGPSFIDVTWGAGGHLS
DLTCEMVKVAQTTYGLETCMHLTCTDMGKAKIDQALKDAYNAGCTNILALRGDPPREKEK
WQATAGGFRYAKDLVTYIREKYGNHFDIGVAGYSEGCDDQKDADLLIDHLKEKVDAGATF
VVTQMFYDVDIFIDWHEKCRAKGINVPIIPGIMPIQTHAAFLRRANWSGCRIPPAWTEAL
DPIKNDDSAVREVGKGLIAEMCRRLLDAGIIHLHFYTMNLAQASKMVLEELDMIPDLESP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAFGELDA
YGVGLKGTNEQNVKLWGKPESIKDVAEVFVRYMEGKLETLPWSEAPITNEADSIKGDLIE
LNRRGLLTINSQPAVDGAKSSDPTVGWGPRNGYVYQKAYLELLISPEIISELITRIERTP
DITFYAVNKHGDLKSNAPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFFRLGKDW
AECHPSTSPSRYLIEDIMDTWYLVNIVHNDFHVGHGIVPLFDGLSVQDMDKPLHSINGIN
GTNGTKEASTNGTAASS
>A0A7Y0BD04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. R302|TrEMBL
MNPASVNPTPVNPTPTFSFEFFPPKTDKGERTLWDAIRRVEALGPDFVSVTYGAGGSSRE
RTVEVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPMGP
WTPHPEGFTYAHELVELVRSLGDFRIGVAAFPERHPRSADWESEIRHFVAKCGAGADYAI
TQMFFDPEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSGAAFPEDLAHRLEA
AKDDPARAHRIGVEHATAMAERLLGEGAPGLHYITLNKSTATLEIHRNVLNSRATQPRST
SHVLAAAR
>A0A6L0XSZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania infantum|TrEMBL
MSKLISDAIAAEDVSKWYTSYELYPPRSEKAEEDMMKVLVPNFMRQSPVFLDLTWGAGGR
TSDTTMRLCKDLQHAYPDTPINMHITCTNTPKGLINEALDFAKTHGIRNILALRGDPPRG
EEFRADPDGFACARDLVRYIHDTYGDYFCVSVAGYPEGHPSRIAEDGAISDEDHQKELEY
LKEKVDAGASFIITQLFYDASLYVQFVKRCREIGITVPILAGLLPITTYAGFVRMVSLCK
TSVPSDVKKRVEELKENPDGLKEYGVEQCVQMIECIRTSGLDYHHLHFYTLNNSAQTFKV
LKRLNALVE
>A0A6L6HIX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia sp. CPCC 100877|TrEMBL
MDSFKKKTFSFEIFPPNSQVAATALIDTLNELKGLTPDFISVTCSNNKANIETTTIKIAD
HVNNELQIPAVAHLPAAYLSKAQVEKILLTLKEKGINKVLALRGDIIEGIPVKKDFQYAS
DLVHFIKNFDGSFEVEGACYPETHPESVNRVVDFYHLKEKVDAGCDQLITQLFFDNETFY
EFQERSAIAGIKAPILAGIMPVVNRNQALRLFRTSRTALPKKFVNILERYEHSPIALRDA
GISFAVEQIVDLVTNNVDGIHLYTMNQSQTAITIHKATASLFDVVNQDENSFHIA
>A4U3F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum gryphiswaldense|TrEMBL
MNLPIAAASAKPVSVSFEFFPPKTEKMQETLWECVKRLEPLAPSFVSVTYGAGGTTRERT
HDTVVRIARESSLKPAAHLTCVGHSQGEVDDIARRYWDEGIRHIVALRGDAPEGSGAYQP
TPGGYAYAVDLVKGLKRINDFEISVAAYPEMHPDAPNADFDLDNLKRKVDAGATRAITQY
FFDVDVYRRFIDRVRAAGITVPVLPGILPVTNFAQVQKFSAACGASVPAWMAKLFEGLDN
DPETRRLVAATVAAEQCRALAADGVTDFHFYTLNRADLAYAISHILGVRPKAQ
>W9E8N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterium aotearoense SCUT27|TrEMBL
MPKSINLCQKLKNKQFVITVEISTPKGADISNSIEEARKLYGIADALNITDCPMANMRMS
PIALAHLLQNHLNIETIFHLTCRDRNLIGLQAELLGAYALGVRNILALTGDDPKRGDVPQ
ATGVYDVDSVGLVKIAKSLNDGFDYSGNKLESSTNFCIGTTANPNDLRSESIEKLKTKIE
SGASFIQTQPVYDEEILYRFLDAVKQFDIPVLVGVLPLKSYKMAVNLNEKVPGIEIPEKI
IDRLKNGEKGEGTKIAIEFINKIKDKVGGVHIMPLGKTDIVVDIVNGVKNIGQNDIEEVL
>A0A2V4H1D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. LB-090624|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARDFEADLGNFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLALWNNLKLPR
>A0A0Q7F0E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. Root418|TrEMBL
METHNFSIEFFPPKTAEGAEKLRAVRAKLSELHPKYFSVTFGAGGTTQTGTLDTVREILA
AGEDAAPHLSCVGGTRASIRAILNEYKSHGIKRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQAKSPQDDLLAFERKVKAGANAAITQYFYNADAYFNFVE
QTQKLGIQVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VGSLCERLLAGGAPGLHFYSMNQAAATTALWQRLV
>A0A4S2UVY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. A0642|TrEMBL
MALGTPSTRTDHARTVREMLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVGPSFVSV
TYGAGGSTRAGTVKATQDIAAESTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMAEWVEHPEGVRYAADLVRLIKEAGDFCVGVAAFPERHPRSPDWDTDIRHFVD
KCRAGADYAITQMFFDPESYLRMRDRVVAAGCETPIIPEVMPLTSVRQLERFAQLSNATL
PEDLKDSILAAKDDAAAVRSIGIDFATRFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A7X8B5Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium sp|TrEMBL
MSSHESIGELLANTSQATFSFEFFPPKDEAGQELLTRTIAELKPLKPDWVSVTYGANGSS
RQRTLNATMAILATTDFRVMGHLTCTGQTVDEIKAVIDAYGDAGVTNILAIRGDMPGGAS
EPWRAHPGGLHNATELVELIASRGDFSIGVAAFPDGHATSTPELDAQILLGKQQAGASFA
VTQLFFELGHYFEMVGRARSAGCTIPIVPGIMPVTSVKQLGRFAEMSGADIPAEVARRLL
SVADDPDQVRHTGAQIAAELCERLLAGCAPGLHFFTQNRSRATREILAMLRADRPSGRG
>C4GEB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shuttleworthia satelles DSM 14600|TrEMBL
MQIREYLKEHTLLFDGAFGTYYTKQFRPEKEESFFPEYVNVSRPDRVKAIHRKYLSAGAH
AIKTNTFGAYPGILMKDAGETKKLITAGFSLAEEALLNHLSKDVKNRPETTGEFARRAGQ
ERSAEASGEEDYFIFADLGPAPGEEEKERILAYQMAIDSFLETGARYFLFETLPEEKTVL
EAIRYLKDQCPGAYTISSFAVMPDGFSSEGCNYRDMLAAAAGESAVDAVGLNCMSSVWHM
DHLIRQIPDPGKPLLLMPNAGYPVVRGYRTVFEGNADYFARILARDAGQGVAMVGGCCGT
TPDHIRLLADRLRENPVRHQGGQGPVFKEPDPALGQDHGKRSDQHLYAATGSDGNSSDKG
SRDSGLSDRGLSVSKDQDAFYQKLMSGRKVVAVELDSPRGCDITRFMEAAENLKEAGADI
ITIADNPIAKARMDSSIVAGIIRRQVGLDALPHMTCRDRNLNATKSLLLGNYAQGIRNVL
VITGDPIPSARRDEVKVVYQFNSRKLMAYMKALGQEEGTFPSPMHIFGALNVNARNFEIE
LDRAREKVQAGAVGFLTQPALTTEAIANICRASETLRAENSRIRLLGGIIPVISERNGRF
MQSEISGIDVPDALIERYVGKDRADCEEIAVDSSLELAKTMEDAVDGYYLVTPFMRDYLI
RRIMERLPGR
>A0A414DH05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospira eligens|TrEMBL
MKYTGTAGILYDRLKSEILVADGAFGTYYAKKYDTGSLPELANLQASDRVLSIHKEYIEA
GAKIIRTNTFASNTVCLGAGFDEVRNNIKNAVDIAREAVKGTDVLVAADIGPIPGENMIE
KEHIEKEYVDIVNVFKECGVDIFVFETFPELGFIDKAIENAGENGFVITQFAINQFGYSS
AGFSARKLIEEAGKNSYIDACGFNCGVGPGHMKKLVQSLINRNDKYFAVLPNAGYPQVVS
GRMVFDDNNAAYFSQIMHDLAEDGADIIGGCCGTTPEYIRQMVLKIADVVHMKNASIEEE
ISEKKTANDVSFYKGKEGRKLIAVELAPPLGIDDEKIMDAAFLMKESGVDVLTFPDSPSG
RTRADSILMAEKVSRETGMCVMPHICCRDKNAIAMRSQLLGAHINDINNFLVITGDPIPS
VVRASVKSVFNFDSVGLMNIISDMNQEQFAGEPVIYGGAINQGRVNFKVELERVKKKMEA
GATFFMTQPVFSDEDIDRLRQIKEQTGARILCGIMPFVSLRNATFMKNEMTGINVTDEIL
SRYRADMSKEEGEETGIQIAREIIAKTTDFVDGYYFSFPFNRVHMLKKIIGKNNQ
>C2RD96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus m1550|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1W6CIZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum sp. ME-1|TrEMBL
MSLPRSELPIAAASRRPVSVSFEFFPPKTDKMQQSLWECIERLAPLAPQFVSVTYGAGGT
TRERTHETVVRIARETPLKPAAHLTCVGHSKGEVDDIARRYWDEGIRHIVALRGDMPDGQ
AYVAHPQGYAYAADLVLGLKRIADFEISVAAYPEKHPDAPSAGFDLDNLKRKIDAGANRA
ISQYFFDPAVFLAFRDKAAKAGITVPILPGILPVTNFAQVQKFSAACGASVPDWMADLFA
GLDDDPETRRLVAATVAAEQCRILAAEGVEQFHFYTLNRADLAYAISHILGVRPKNAAK
>A0A0P6R7M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter sp. 11ANDIMAR09|TrEMBL
MTSPEISFEFFPPQTLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRDLTRDAVKTLHG
SSGLNVAAHLTCVNASRAETLEIAENFAAVGVTEIVALRGDPPKGSGQFVPHPDGFANSV
ELIEALAATGKFTLRVGAYPDPHPEAPNAQADVDWLKRKLDAGADEALTQFFFEAETFLR
FRDACAKAGIDGDKLVPGILPIENWKGARNFAKRCGTVIPTWVDEAFEKASRDDREDLLA
TAICTELCDDLLQEGVRKLHFYTLNRPELTRDVCFALGVTPNVSLENVA
>A0A0A2HW94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp. Tol-SR|TrEMBL
MKTESKLEKVLAAGHLAVTSECGPPRGCLPDKVREKGKYLEGVVDAVNVTDNQTAMVRMS
SLAASVILKQEGLNPLLQVVSRDRNRLAMQADIIGAYSLGINTMLCLSGDHTKFGDHPMA
ANVHDIDSIQMIQMVKQMRDEGLFQGGAEIKSPPKMFIGAAANPFADPFELRVLRLAKKV
AAGADFIQTQCIFNVDKFEKWMEGVRSMGLHKKCYILAGVTPIKSVGAARYMKNKVPGMD
VPQEIVDRMAAQPKEKQPEEGITICIETIERLKKIEGVAGFHIMAIDWEEKVKEIVERAG
LLPRPVV
>A0A1Z5JDX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fistulifera solaris|TrEMBL
MTKIIDILTNHDGDKPLISLEYFPPRSDVGVQNLHSRMDRMKNVLSPAFTDMTWGAGGST
AELSLDLALHAQNTGHLANLHMTCTNLGENVDPKEAIYKALQKAKDGGIRNIVALRGDPP
AGETEWKAAEGGFNCALDLVKFIREKFGDDFGISVAGYPEGHPNAITEIADPSTLTPEEL
ARSSHFDGKTYCCLEADYKKEMDYLKQKVDAGADFIITQMFFDVTIFTTFVADCRKWGIQ
CPIVPGIMCINAYAGFRKMTQFCKTRVPQSLDEKMEAIKDDAEAVKEFGVTFGAEMCQGL
IDSKTTPVLHFYTLNLEKVVYGILDKMGVTQNALAAADEADAHSQIAKGSAWARVGDKVS
TQYGEGVVVEQIASTGVAKIELNKWIMAGGQKPVAYLQKGQYTKIF
>A0A1W6Z4C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella genomosp. 9|TrEMBL
MTDTSTPAYSLEFFPPRDIAAQERLLRAAKQMLAIHPRYVSVTFGAGGSTREGTAGTVRM
LRNLGVSAAPHLSCVGASREDLRAILTAYREEGVRQLVALRGDLPSGMGGDAGELKYARD
LVAFIRQETGDWFHIEVAAYPEMHPQADSPSSDLDHFVEKVRAGADSAITQYFFNPDAYF
DFVDRVRAKGVSVPIVPGIMPITNHTQLVRFSQMCGAEIPRWIRLRLAEFGDDKASIRAF
GVDVVTDLCRKLLDQGAPGLHFYTLNSAEAPLAIWNNLTRK
>A0A2S7NXC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rutstroemia sp. NJR-2017a BVV2|TrEMBL
MEKITAKIAALPPDTSYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRTLVDQALEDAKALGIRNILALRGDPPRTDE
YRAVDEKDGQSPAMDWDFEWAIDLVKYIRKQYGDYFCIGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVEAYNHFEKRLREHPSGAFKNIPIIPGMMPIQSYQMI
KRTTKLSHAKLPADIMTRLDTVRGDDEMVKKVGVDILSEIVEHIKVTKSQYSGPRGFHFY
TLNLEKSVSFILERTNLIPEATDDDSEALEAELLPPISHLTVNGSHKRSSRRQSSVGSDP
HNRIIITAAQASNPSYEATALEAGVPAEAVNSRANTLAISEGEGSLGREATWDDFPNGRW
GDARSPAYGEIDGYGVSLHMSINQAIKLWGHPASTSDITNLFLRHIEGQLTAIPWSEEGL
NEETNSIKKQLLGLNKKGWWTVASQPAVNGVRSSDPIFGWGPKNGFVFQKAFVELFIPAS
DWKTLHSKLTSPELCDTVSFYASNAKGDFVSSDQGGAGSTNAVTWGAFPGKEIITPTIIE
EVSFRAWTEEAFGIWGEWARVYGAKSETRKVIEGIMDDVWLVNVIHHAYVEKEGLWDLLL
N
>A0A0Q8CYB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. Root604|TrEMBL
MLPISFEFYPPKTDEQRAQLDKTAAKLKARKPHYVSCTFGAGGSTLSYTPDTVRHLRDAH
SLDAAPHLSCVGGTRAEIRQLLNQYREIGCRRLVTLRGDLPSGMASAGDLRYANELVEFI
RAETGDHFHIEVAAYPEMHPQARDAHSDLENFKRKVRAGANGAITQYFYNADAYFRFVDD
VRAAGIEVPIVPGIMPIANFSQLRRFSDLCGAEIPRWIQQRMMAYGDDVDSLREFGADVV
AQLCQRLIDGGAPGLHFYTLNLSKPTLSVLSRLS
>A0A1G2W1D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium sp. RIFCSPHIGHO2_01_FULL_69_31|TrEMBL
MSPAQTALGPVARAGVGGQPRPGVSFEFSPPKTAEAEENLWAAIRRLEPLAPTFVSVTYG
AGGSTRDRTHRTVLRMLKETTLKPAAHLTCVEATRGEVDEVIRDYWASGIRHIVALRGDP
PGQIGGVYTPRADGYRNATELTAGIKAIGDFEVSVGLYPHVHPESSGIDHDIDVLKAKID
AGATRAITQFFFDVDGFLRFMDRVRKAGVAIPISPGIMPVTNYAGLKKMSGPIGIELPGW
LGNLFEGLDKDPETRRLIAASVASEMCARLAEEGFGDFHFYTLNRADLTYAICRILGVRE
TPPEPKEAAA
>A0A0Q9Q0T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Soil766|TrEMBL
MKLDLRAALQQEILTGDGAMGTYLYQMGFPVGISYEELNLLRPETVADVHRRYFEAGARL
IETNTFSANREKLSKYGLEGDVEAINRAGVELARNAVGEDAYVVGAIGSIRAGKRKNVRT
SEVEQSLHEQISILLDSPVDGLLLETFYDLEELQLALRIIRSMSGLPVICQFANEGTGST
QDGVPLQEAFLRLRDEGADVIGFNCRVGPNGILRSMEKITPIPGIPFSAFPNAGLPDYVD
GHYTYAATPKYFAESALRFADLGARIIGGCCGTTPEHIAAVAKALQGYVPAAPGTAPAGA
AAIVIEPAPAKPAPPVGIPSLLDIVKQRKTVIVELDPPKDLDIEKFMQGSKALQEAHVDA
ITMADNSLAVTRMSNLALGYLVQERLGARPLIHIACRDRNMIGTQSHLMGLHALGIDHVL
AVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFVVGAAFNPNV
KHLDKAVQRLERKIEAGADYIMTQPVYDAKLIEDIYEATKHLQIPIFIGIAPLASGGNAE
YLHNEVPGIRLSDEVRARMDGLKGPEGRAMGVEIAKELLDTAMQYFNGIYLMTPFLAYEM
CVDLTNYVWEKSKRHDFHLYPLSK
>A0A7J8YB83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium aridum|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIISVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVVRVKEDVRPIFWSNRPKSYITRTIGWDQFPHGRWGDSRNPS
YGALTDHQFMRPRARDKKLQEEWATPLKSIDDIKEKFKSYCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGKYKC
>A0A5R9LXB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. So13.3|TrEMBL
MTPVVNAPTTSNNLRDVLAAGQRTFSFEFFPPKTDAGERVLWDAVRRIEAVGPTFVSVTY
GAGGSSRDRTVDVTRRIATETTLRPVAHLTAVGHTVAELRQIVGRYADAGIRDVLVLRGD
PPGDPRGPWQRHPGGLDHAADLVELVRSIGDFSIGVAAFPERHPRSLNWDDDIRHFVDKC
RAGADYAITQMFFDADDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDATFPP
ALAEQLAAAQDAPATAHRIGVDHATRLAQRLLDAGAPGLHYITLNRSTATLEIHQNTRSA
DAVPHRR
>A0A1C1A8U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus pectinilyticus|TrEMBL
MKLDLRSALQREILTGDGAMGTYLYQMGFPVGISYEELNLLRPETVADVHRRYFEAGARL
IETNTFSANREKLSKYGLEGDVEAINRAGVELARNAVGDDAYVVGAIGSIRAGKRKNVRT
SEVEESLREQISILLDSPVDGLLLETFYDLEELQLALRIIRSMSGLPVICQFANEGTGST
QDGVPLQEAFLRLRDEGADVIGFNCRVGPNGILRSMEKIAPIPGIPFSAFPNAGLPDYVD
GQYTYAATPQYFAESALRFADLGARIIGGCCGTTPEHIAAVAKALQGYVPAAPGTVSAPA
VRVIEPAPAKPAPPAGIPSLLDIVKQRKTVIVELDPPKDLDIEKFMQGSKALQEAHVDAI
TMADNSLAVTRMSNLALGYLVQERLGARPLIHIACRDRNMIGTQSHLMGLHALGIDHVLA
VTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQRANFVVGAAFNPNVK
HLDKAVQRLERKIEAGADYIMTQPVYDAKLIEQIYEATKHLQIPIFIGIAPLASGGNAEY
LHNEVPGIRLSDEVRARMDGLKGPEGRAMGVEIAKELLDTAMEYFNGIYLMTPFLAYEMC
VDLTKYVWEKSKRHDFHLYPLSK
>A0A6M1PVF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parapusillimonas sp. SGNA-6|TrEMBL
MTSKQAISLEFFPPRDVAAQEKLVRSAKRLLALHPAYVSVTFGAGGSTRSGTVETVKLMR
NLGCDAAPHLSCIGSSKRVLGDILDSYRELGIKRIVALRGDMPSGMGGDAGELHYARDLV
AFIREHSGDWFHIEVAAYPEMHPQAGSAEADLNHFAEKVRAGADSAITQYFFNADAYYDF
VERVRGKGLDIPIVPGIMPITNHAQLARFSTMCGAEIPRWIRLRLTDFGDDKASIKAFGI
DVISRLSQDLLDQGAPGLHFYTLNNADVTMAIWKQLRLS
>D5DBM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia megaterium (strain DSM 319 / IMG 1521)|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINVAGVKLAKQAAKDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLNEGVDGLLFETYYDFEELKTVLTLARKETDKPIITHVSLHDIGVLQDGR
PLADALKELEALGADVVGLNCRLGPYHMIQSLEEVPLPDRAFLSAYPNASLPAYVEGKLE
YETNEDYFVESARLFREQGVRLIGGCCGTTPAHVRAMSSALKDLPPITSKVVKMRPAVTV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRIRGEVEGLAIAKNLIDTAYELFDGIYLITPFMRYEMTEILTRYI
HDKQLVTSERKI
>A0A8C0QIG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chelonoidis abingdonii|TrEMBL
MVNEPHSASSGSASSRSDGSSSGSEGSKDSSRCSTPVLDAERHERLREKMRRRYDSGDKW
FSLEFFPPRTANGAVNLISRFDRMGMGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETVLHMTCCNQTKEEITGHLQKAKHLGLKNIMALRGDPIGEEWEEEVEGFNYAVDLV
KHIRCEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVSAGADFIITQLFFRSETFLTF
MKDCQAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKEVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVSGLHFYTLNREVATTEILKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIHRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELMSEESLFEVFTCYISGKPNRKGHKVTCLPWNDDPLAAETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEITTALLKVLKTKKYELRVN
YHIVNVWGENITNAPDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKVRALRHSAFVLPC
TNIGKP
>A0A1X7JRI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenibacter troitsensis|TrEMBL
MGGVAIPERHIKKGDEHIRLFDKVDKGCSFFISQCVYSVNNTKDFLSDYYYTSIETDRDL
VPIIFTLTPCGSLKTLQFMEWLGIDIPKWLNNDLKHSNDILSKSIDLCKNIAIEILDYSV
TKNLPIGFNIESVAIRKEEIEASIELLKDIKGLMNR
>H0HTK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium alhagi CCNWXJ12-2|TrEMBL
MNQFRFSRRPDIGDKVSVSFEFFPPKTDEMEARLWNTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGASRDAVNAVIREYDALGIKRFVALRGDPASGVGQ
AYTPYPGGYENGAELVAGLRAISDFDISVAAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDIYERYVERVRRAGIYIPIVPGIQPVHNFRQVANFSSRAGAHVPAWLAERFE
GLNDDPQTHALVASAVAAEQVMDLVERGVSDFHFYTMNRADLVVAICHMIGIRAHDATAA
AEGFAAA
>A0A653X0Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas titanicae|TrEMBL
MSSHEHPLGISFEFFPPSTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTREVVR
AVGESGINTAPHLSCIGSEKAQLRDLLAQYREEGVESLVALRGDMPSGMGSIGELRYANE
LVEFIRTETGAHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLEGGAPGLHFYTLNQAAPVLKIVDNLAG
>A0A420DDL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epilithonimonas arachidiradicis|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFKPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEPSVGGHKYASDLVKQIHDLGIGEYLHGKIESDVDNSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKFFDFVKQAREIGIDVPIIPGIK
PIATKTHLQMLPQVFKIDLPETLINEVLKCKTNNDVREVGIEWAINQSKELLDFGIPVLH
FYSMGKSDNILKIGREVF
>A0A238VUK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. DSM 44272|TrEMBL
MVRARGFERRSTGQPSRVQPESATAGRLGCPKRMVFGPCGGVREDERCELAQHRCVFLGE
PLVGWPDPPVAPPDPAPDGLLARAARAPVVLADLSAPAFDTAAVRRVVDILGPVSDALLL
GEHANRPDFPPTMLAAEALGAGARLWATLACRDRNRVVLEQELAGLAALGVDGVLCVTGD
GRGPGVRPGASQVFDLDGVRLAALAAAQGLQIAVPEAPEAPPVDLRPARVAEKQRAGAQL
CVLNHVSTPARVAAFVSAARAAGATLPFIAGVAVYTDERSARVLQRFPGLHLDDAVVERV
LTAPDPRDAGIAAAVAEARALLAVPGVVGVNLSGMGSARDADDGARIKAEVAAEVRGMA
>A0A3N1GG42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Couchioplanes caeruleus|TrEMBL
MSLGLPSRLPTSPAIGELIRRPTPTFSFEFMPPKTPEGEQLLWRTIRELEPLRPDFVSIT
YGAGGSTRDTTVDVTERVASETTLLAMAHLTAVGHSIAELRNVIGRLAGAGIRNVLAVRG
DPPGDPNGEWVRHPEGVLYAEDLVRLLREAGNFSVGVAAFPYKHPRSPDIDSDTRNFIRK
CRAGADFAITQMFFEADEYLRLRDRVAAAGCDTPIVPGVMPVLRMATIARSAQLSGAPFP
PALLKRFERIADDEAGVRRLGIDLCSEMCRRLLDEGVPGIHFITMNRSPATREVWQHLTG
AAAAPAAA
>A0A4R2KYG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatocurvus halotolerans|TrEMBL
MASSSPISFEFFPPKTEEGRERLLEKTTPRLQALQPEYFSVTYGAGGSTRDNTLDVVTAL
TKGGYSVAPHLSFGTDDNDAITALLDHYRDLGVKRVVALRGDMPSGVGGGRLVYASELVS
FIRKHSGDHFHIEVAAYPEIHPQAESYDKDIEHLKHKLDAGADSAITQYFYNVESYFYFL
DRCAAIGIDKPIVAGIMPITNYENLARFSRNCGADIPRWISKRLEGFAGCKESVTSFGIE
VVTQLCQTLLDNGAPGIHFYSMNQVEPTRQICRNLGL
>C2GX42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum ATCC 55813|TrEMBL
MFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTISKEYG
IPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIEGEQLVGEFNHASDLVSYIR
SVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFLDKAR
AAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWGDDIQSLRTAGILYASE
QIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFLGTQG
>Q3K5D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens (strain Pf0-1)|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVTEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A8F5KTQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae|TrEMBL
MQNYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYG
ANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGDE
PAGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVI
TQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEG
LDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A7Y3HAM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
LHASTVFDVTGRELIAMAAGLDEDKTAAAPFFIGTGVKAHRARKGWRAEALNQKAELGAQ
FIQTQICYNLDLMKHYLQRLVEARATWDFSVIASLAPLPSSETARWVKENMPDSKIPKRL
VQRIEQAADPEQEAVLACAETMQAMSEIPGLSGIHLMTTGDAELIGAAIDTSGLARTEGA
GQQEAQA
>A0A6L7RB60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRRSELAAFLRERPRVGDGALGTALYAGGIASRRSFEDLNRSDPDRVRAVHTAHLAAGAE
VISTNTFGANPWKLGRHGLASEVAKINAAGARVARSAVRPGSLVLGSVGPSGEVVGPFDE
EKAPEFAAGFREQITALVESGVDAVLIETFTSLTEARLALSAAREVAPDIGVIVLMTFSE
QATTVFGVAADQAAGTLERDGADAVGSNCGVGPDTTLTALERMRDAVSLPLVAQPNAGIP
ERTEGRFLYPSSPDYVAHYAKRYLRLGVSLIGGCCGTGAEHIGAVAGVVRAASAGARADR
VRAPARPAAAAPAEEAPAEIPAVPVPERSGLARCLAEGRFAVSVEMDPPRGAEPGKFLAR
VGDLADAGIRFVNVADGPRATARMSAIAFAALLERSGEVETILHYQCRDRNLIGIQSDLL
GAHALGIRNLLAVTGDPPKLGDYPHATPVFDVDSIGLVRILRGLNHGLDLAGNPLGAALP
FHIGVGANPAAADLEGEMGKFERKVQAGAQYCLTQPVYETRLLERFVKDVRGYGIPVLAG
VLPLVSSRNAEFLHNEVPGMSVPQPVRERLAAAPTRQRAREVGVSVARDMVAAARDLVAG
VYVMPPFNRFDLAIRSVTGLV
>A0A7X7VFG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MADPVFHVELQTPKRASEDIDKDLETFADKYRKVVDAGWTVCITDNPMGLLSYGAMETIE
LMELPVRPGQLMVHLNTFHPRKELDGILAAFGDAGGRDLLVVSGDGSQKLHRLEPAEVGT
PGPTVTSVELLRYIDREFPGRFTCGVAFNPYEPQDAELEKMKRKVDAGAAFIITQPIIGR
DDRLAGLAPFGLPVTLDAWMSKKLHLLSECVGHEIPEGTPYDPMENLRELRRNYPDYGLY
LAILGFKTQYPLLRDVWKGGAES
>A0A7V4SNP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MGAMTSRREAWKNWMAESVIVADGAMGTLLRARGLPAAACVEEATLSRGDLVYDAHRDYL
HAGAQILTTNTFRANRLHLAAQGHADKLRDINARGVEIARRAAHGAPVWVGASVGPLKVM
LKPYGDVSEDEARDVCREQIAALAEAGPDLFILETQQSVVEALFFLEACRELAPDVPVLA
SLTVSREGRTFFGDRPVEGCRRLAAAGADVVGINCSVGPADTLPFVEEVARSVDHPLAVM
PNGGYPAEVDGRIVYLSSPEYVAEYVRRYVDLGVNVVGGCCGTTPETIRAISRLLRGRPP
AGRQPSERGTLVVEAPAAAPPSSPAETPGGFFGKLGTSFVVTCEIDPPKGPDAGPAVEAA
RLLKRAGADAVNIAENPMARVRVAPMALAHFIEQETGLSTILHMTCRDRNLLGLQSELLG
AALLGVDGILALSGDPASLGDFPAATSVNDVNVVGLVKIVASLNRGLDFSDNATGAPTHF
GIGVGISLTPRDPEAEVLKLRERAEAGATFALTQPVFDLDDAARFLDRVRDIPLAVLPGL
LPLAGLKQALYLHNEVPGMRVPDPVLRRLEALPAREDQMAFGVDLARGLLEGIRRIAPGA
YLTSGGRRAAVLADVLSG
>U2X6B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus kaustophilus GBlys|TrEMBL
MLDKLKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTNTY
GANYVKLARYGLEDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSVVTLEEVKRT
FREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGTPL
ADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLVYE
TNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIAAMAKALSDRTPVTEKTVKRRAVSVSVQ
ADRPAPSPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLATPR
ISNAAVATIIKEQLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIGDF
PGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERMEK
KIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGITLS
DEIRARMAACGGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYIHE
KEAAAKERKVVHG
>A0A2V7UQJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSTPSRRSGPTPLEFLEDHVLVFDGGMATMLYQKGVFLNSCFDELNLSRPSMVQEVHRAY
IQAGAEAVETNTFGANRYKLQGFGFQDKVSEINRAGARLAREAAESRAWVAGSIGPLGLR
IEPWGPTSVEEAEAAFREQAQALLEGGVDFFVLETFTDLNEIHQAIKAVRGLCPLPVIAQ
MTIEEDGNSLYGTAPEVFTRRLDEWGADVVGINCSVGPQVMLECLERMVKLTSRPVSAQP
NAGRPRSVDGRNLYLCSPEYMASYARKFVQAGAKVVGGCCGTTPEHVKAMKSAIRALRPA
HVAVEISLPAEQRVEVHPVDRARKSLLAAGLVKGRLVTSVEITPPKGFDTSRVMAGAKML
KGAGVDAINIPDGPRASARMSAQALAVILEQQVGIETVLHYCCRDRNLLGMQSDLLGAAA
LGLKNLLIITGDPPKMGDYPDATAVFDVDSIGLTNMVTRLNHGLDLGGSPFAPPTAFLVG
VGANPGALEMDHELRRFQYKVEAGAEFAITQPVFDVKQLRSFLKRVEEFRIPIVAGIWPL
TSLRNAEFMNNEVPGVHVADEIMERMRRADSQGKAREEGVTIARETVQEVRDLVQGIQVS
APFGRFQTALEVLEGVIPRAV
>A0A2V7W5N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MQDFIQAIADEHVYLFDGAMGTMLYAKGVFINKCYDELNVRNPEIVLEVHRQYVRCGAEI
IETNTYGANRVKLRGFGIEEELREINIRAAELARKAAGDSVYVAGAIGPLGIRIEPYGPT
SLDEAREFFREQAEALRDGGVDLIIAETFSNISEIEQCIAAIHEVCNLPVVAQMTIGTDG
RTVYGDAPKVIAQRLDRARADVIGLNCSVGPDLLLDAVEELASVTAKKISCQPNAGLPRD
VNGRQMYMASPEYFSKYAKRLIHKGVKFIGGCCGTTPEHVKMMGDAVRPLSPRRTFVIVE
RNGKNGEKAPGSEPVPMETRSNWGRKLAAGEFVTTIEIVPPKGPNPDAMIESVRSIKAAG
VDAVNVPDGPRAQNRMGAIAVAVLLQQRVGIETVLHYCCRDRNLLGMHSDLLGCGALGLR
NLLLITGDPPKMGPYPEATAVFDIDSIGLTNMASLMNRGLDLGGNPFGEPTKFTIGVGVN
PGHLDLEYELRRLEWKVKAGAEYAITQPVFDVRLLENFLRRIEHMNLPIVAGIWPLLSYR
NAQFMNNEVPGVSVPDDVIERMRIASDKGKEFALHEGVTIARETLSRVRDRVAGVQVSAP
LGRVDMALQVFGEAEPAVSSRA
>A0A501W0R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. D2|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A448QSA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus equuli|TrEMBL
MPGILPVSNFKQLEKMAKVTNVRIPSWMQKMYQGLEDDQTTRNLVGASIAMDMVKILSKE
GVKDFHFYTLNRSELTYAICHTLGVRP
>A0A1B9DZP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium crassostreae|TrEMBL
MKVTQHIEKAKEKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVK
KENGLLDKKMTRMRPGTLGICASIKHKYDVDTIPHVLCGGFTKEETEYLLVDCHYLGINN
VMALRGDAMKEEQSFVATAGGNKYAVDLVQQIKLLNQGKYLHEVMHIDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNTKYFEFVAKARAMGITVPIIPGIK
PLAIERHLQILPQIFRIDLPEDLIQAVADCKTSQAIRQVGIEWAVQQSLELKAAGVPVLH
YYSMGKSENIRQIAHQVF
>A0A399YEZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTGVTDPTTRRLLTGARYEVLPTASILDQVREHVPTSVTVSVTASPGKGLGATLDLAGEL
ARAGYDVVPHLAARMISGRAELAAIVERLREQGVRRVFVPAGDAQVPAGDYVQSLDVLHD
LREMGDPFPEVSITGYPESHPFIEDDVVVQAMWDKRLHATHVVSNMTFDPDLLAAWVQRI
RRRGVTLPLLVGVPGPVERTKLLAMGTRIGVGDSLRFLRKQRRVMTRVVGTGFSTDRFVA
RVAGLAAEPALGVVGLHLYTFNQVAVVEAWRRAALGEPAERPSAAHG
>A0A2G2K4J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus sp|TrEMBL
MGKLAXALXSSSFVVTSELTPPKGTDLDELFAKADLLRDLVTAFNLTESHAARMAMDPVA
VGHLLIDRGIEPIVQMTSRDKNRLAIQASILGAAALGVSNVVFMGGDPPKNGDHPDAKPV
FDLFASQLLEAACALNNGTDLSGNALKGTPQLTIGAVANPGASDLALEIDNMKRKADAGA
EFFQTQAIYDVAAFDRFMTKAKPEXPVLAGIIPIKSVKMAQYMNDKIPGVDIPQDLIDKI
DAAGDDKAKVADISIVIASNTVRELRDMTRGVHVMAIGWEDKIPAILDRASA
>A0A523EYB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MALIVSASRSGPRPDSSISPSKPLRPLSVTTRRPSTSSPGSRRRVDLLTRSEGWIRIAEV
NPPELPNQRHRSLSPVWTRVLVTDNVFGRIRVSPYAFSARITHDTPDVRPTVVVSTRDRN
ILAIESEVRGALGNGVDSFLVVVGDTVPHIDHLAHHHEIVDHLTNLQKDLPDFEVGMPTR
FKEWQFRRRIDLGTQFFVAGPVIDPDVVEQQISQLNLRDQDPPVFLMVIPPFSIDWIDRM
ESIGAVPVGDRLKQRLDHLSPDVRRKTAWQITSEMERRARDAGCAGVILMGLKFDSVVEE
APGAWPILD
>A0A2V7ZV06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
VGGQPIGAPTAFHIGVSINPAATNLDQELRRFEYKVDAGAEFIVTRPVFDVRAFEQLLRR
LEPAGLPVIAGLFPFESARNAEFMANEVPGVRVPDALLERMRKSDGRSGGAAEGVAIARE
IASELRSAVQGFQVSTQSGDVESALSVLDGLR
>A0A2V8LSS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKLRDLYARPGLTFSFEFFPPKTPEGDAALFREVEILKTLNPAFCSVTYGAGGSTRDKTV
EIVTRLHDDVGLEVMCHLTVVDQSKDDVRAVLNRLKANRIENIIALAGDPPKGVTDWRPH
PDGFHYSTELVQEAAAYNWFSIAVAGFPEVHPRAESRESDLRYLKLKVDAGADAVITQLF
FDNEDYYRYVDDCRKIGIKVPIVPGILPVQSAAQTRRFAAMCGSGIPARLDGLLAKVEND
AAAELDLGIEYATEQCEGLLRFGVPGIHFYSLNKSRSVKAIFENLSLLEPNSGTDA
>W8S604|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibacterium elongatum DSM 19469|TrEMBL
MNLSQPSAYATKLDEKSRIPIAMTPPRVSFEFFPPKSLEASFRLWETLGVLAPLAPEFVS
VTYGAGGTTRALTHDAVKTIHKHYGVPVAAHLTCVDATRAETLEIAESYAQAGVTQIVAL
RGDPPQGQGTFTPHPDGFASSIELIEALADTGKFTLRVGAYPDPHPEAEGLQACVDYLKR
KIDAGAHEAITQFFFEADAYFRFRDACADAGITARIIPGILPVNNWTRVRRFAEATGAVI
PAWVDEAYDKAIRDGRETLLSTSLCAELCSTLMEGGVEDLHFYTLNTPDLTRDVCAALGV
TQPVDLSEVA
>A0A126SVN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium angulatum|TrEMBL
MTAPLFSLEVFPPRRNAPVGTIYDTLDGLQGLAPAFISVTYGTGKSKDRTATARIANTIR
GEYGIPAVAHLTAQYLDREAADVALDLFEVAKVDGVLALRGDSVEGQTPAGVFEYASDLV
SYIRENRPQLKIYGACYPEKHPQAATIDEDVDNLKRKVDAGVTHLISQLFYSNDDFYRFL
DKARAAGIDVPIEAGIMPVTSAKSVRRMSATCEARVPEPVEAMLQRWGDEPAALREAGIA
YASQQVADLIAHGVDGVHLYTMNHPAVTRRIWNNVSALFQS
>A0A3N5PGP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MSNLRDKIKARRFVITAEIVPPLSAGPTKLLHEAQHLKGKVDAINITDAAAGKTSISSFA
AAALLVANGHEPVLQVTCRDRNRIALCGDLIGAAAQGVENLLILRGDDPKGGDQPDAKPV
FDLESADLLKVARDMRDKGELPSARKIDSPPKFFIGAADVPRRPDAKWSPVPLQKKIEAG
ADFIQTQFGFDLEVVRAYAERLRAEGMTEKRGIIIGVGPIRSAKSARWMNENLFGVSVPE
PIIARLEAASDQAAEGRRVCAELITGLKQIPGVAGAHVMAPAQGTD
>A0A2K8Z7F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma pollinicola|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPIKGDNLKSLLDNIEPLMEFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICAAIMHRFGVDAVPHVLCGGFSREETEDFLIDLHYLGID
NALILRGDPAKPFSTFKAKENGYSYASELVEQVANMNQGIYLHEEDTALAPSNFCIGVAA
YPEKHFEASDHESDFRYLKQKIDKGADYIVTQMFFDNKKYLDFVDRCRNEGITVPIIPGL
KPLSTRKQLQILPKLFHLEMPADLVQAVEACENDQQARQVGVEWCIQQGKELVAAGAPVL
HFYTMGKADNVMKIAGALF
>A0A2V9SD44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
GDPPKMGNYPDATAVFDVDAIGLVNIVQNLNRGLDIGGNPIGVGTSFVIGVGANPGVPNL
DEEIRRFEYKVEAGAEYAVTQPVFDLSLLETFLRQIEHCRIPVVAGIWPLVSVRNAEFMK
NELRVSVPNSILDRMAQAKTPEAAREEGIAIAREMLVAVHHMVQGAQISAPMGRYASAVD
VLEALGSSRPATA
>A0A399XRV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MAKISDMLTAGRTFSFEFFPPRSDEAERQLEKALHELTPLQPDYVSVTYGAGGSTKERTR
DIVIEICRDRAFPAMAHLTCMGHTRAELLELLADYAANGVHNILALAGDPPADGSAPTGD
FTYATELIELIREVGDFCVGVAAHPELHPRSPSRESDRRYLAAKLELADFGISQFFFDNR
DYFSMLDELASLGCETPVLPGVMPVVNPTSIARFADMNKAKRTSELWDRFEVLADQPAAL
MDLAVEVAAEQCRELLDAGAPGVHLYTLNRSEAALRIFDRLDLLPPRGR
>A0A4Q3IK21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacteraceae bacterium|TrEMBL
MAGVPLSFEFYPPKTDEQRAQLDRTAEKLKAHAPEYVSCTFGAGGSTLSYTSETVRHLKQ
THGFDAAPHLSCVGGSREEIRELLRLYRALGCRRIVALRGDLPSGMGHPGDLRYASELIE
FIRAEHGDAFHIEVGAYPETHPQSDDALVDLKHFKTKVDAGASGAITQYFYNADAYFHFV
DAVRKLGVTIPIIPGIMPISNYGQLKRFSEACGAEIPRWVGKRMQALGDDVDGIREFGAD
VVANLCDRLVKGGAPSLHFYTLNLAKPTQSVLSRLA
>A0A1F9D8U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_48_10|TrEMBL
MSLEENLKKKRFIVTSEIQPPIGTGVQELIRNVERIRGRVDALTVPELKIEGLVTDTMGT
CRALRDQKFEPILQTTTREKSRIDLQEHLIRASESGIENILAFTEDYRITGDSLQEIMFF
HVDSGKLFSVVENLREGHDVSGKVIPIKTRFCVGSGIDSSWGKKVPDLELKEMEELAKMG
TQYFLTTPIFDLDSFHQFMKRVGPIQIPVIAEVILVRSAEMGLFLNKHVKAGLVPNHIIE
KLAKAPDKERASIEIVSDLVKGLKEVCRGVHFIPIGAEDRISKYLEAAELSAI
>A0A2W0B2A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
PAKEVEGARYLKSVGIDAINIPDSPRASARMSNQALCLLIQQQVGIETVLHYSCRDRNVL
GIQSDLLGGYAVGIRNLICITGDPPKMGNYPDATAVFDVDAIGLVNIVRNLNQGLDVGGN
PMGNAAAFVIGVGANPGAPNLDEEVRRFEYKVEAGGEYAVTQPVFDLKLLETFLRRIEQF
RIPVLAGIWPLVSVRNAEFMKNELRVSVPDSILARMSAATNAEAARAEGIAVAREMLVAV
RGEVQGAQISAPLGRYSSAADVLEALGGNGHKAAAVV
>A0A5B6TXG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. SARCC-RB16n|TrEMBL
MIGRQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFIQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A177KIB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Domibacillus aminovorans|TrEMBL
MTLLDRLKTDVLTADGAMGTLLYSHGIDFCYEELNTEKPEIIEKIHKDYIAAGADVIQTN
TYGANAIKLARYGIENRSRELNAAAIEIAKKAAAPGGQFVLGTIGGIRGIRKSTATNAEI
IASVREQAESLLSGDPDGILFETYYDFEELSESVKVLREMSDVPIIAQVSMHEPGVLQNG
LSLNEALHRLEGIGADVVGVNCRLGPFHTIQAFEGVTLPEKAFLSASPNASLLDVEDGRI
VYESEADYFGRAAVLLRNEGVRLIGGCCGTTPKHIEAAKKRLVGLPPLTEKKVKTKKPIV
IQEAKPSTDVSICEKAKTERTVIVELDTPKTLLTEKFIEGANKLYDAGVDAVTMADNSLA
SPRISNMAMGATLKLQHDVRSLVHITCRDHNLIGLQSHLMGLDALGLHDVLAITGDPTKI
GDFPGATDVYDVSSPELIQLIKQLNDGISFSGKPLKKKANFSVAAAFNPNVRVLERAVTR
LEKKIECGADYFITQPVFTKEKIVDVYEATKHLSTPIFIGIMPLTSMRNAEFLHHEVPGI
KLSDETLERMRACGDDQERAAKEGIQIAKELLDTAAQIFNGIYIITPFLRYDMSMELIHY
INELDALKERGIVHADSSN
>A0A8J5XN54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diacronema lutheri|TrEMBL
MGLAPEPSARIADLARAHQAEKRRFFSLEFFPPRTEAGVLNLQERIVRMAQQGPAFVDIT
WTAGGKSGALSLGLARFCREAGLTAQMHLSAAGMDEAGVRAALDAARAAGIVNVLALRGD
VPAAVEAATDGVRAAPGSGALTFPHAVDLVRFIRAHYGDAFCVGVAGYPEGHVDGESYEA
DLAHLAEKVAAGGEYILTQHFFNVRRFSQFLDDCKRIGINVPVIPGVMPIHNYESFARIV
RFCRTDVPASISAALEPIRNDDEAVKRYGTVLASEMASALFELGCGGVHFYTLNLEQIVT
QVLLMHGFARQPARRLVPWQHARTADSALAPTVALRGGGGEGGGGNGGGDGGGDGGGGGG
REQRAARDESVRPIFWANRPQSYLSRTAHWDEYPNGRWGDRRSPAFGELSSHHTTKLHTL
KASERRAAWGHRLESAADVCATFVRYVRGQIPMLPWCELALANESSRIADKLALINARGM
LTINSQPAVNGAPSHDPDVGWGGAGGIVYQKAYCEMFVSPLTLDAIARHMGRHPTLSFQA
VNARGECVHNLAKNERGGMAPTVTAVTWGVFPGKEIQQPTVVDSEAFVEWKDEAFELWVS
QWASLYEPGSRSRAVLNRIHDEWFLLNVVDHDFQRGDLFCVFTEVAEGLGPAGAADLAP
>A0A6F8SQU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas meridiana|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAARKPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRDETGDHFDIAVAAYPESHPQAPSLDKDVENFARKMNAGANMAITQYFFTADAYF
HFVDKARALGVEQPVIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAF
GTDVVTRLCERLLDGGAPGLHFYTLNQAAPVLKVVDNLS
>A0A3M2QH69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus pseudoxylosus|TrEMBL
MSQLLDKLKSNILVADGAIGTILYSEGLDTCPEAYNLNHPDKVERIHRTYIEAGADIIQT
NTYGANFEKLKVFGLEHRVKDIHQAAVQIAKKAANDDTFILGTVGGFRGIKQEDLELSSI
QYHTEIQVETLVNAGVDGILFETYYDLQELTNIIEATKRKYDIPIIAQLTALNTNYLRDG
TEINHALHQVTASGADIVGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSQF
KYSDNASYFGKVAEQLINEGVRLIGGCCGTTPEHIQYIKSSVAGLNPVTKKDVIPITKYI
NNTEKEPKKQNLKSKVENRPTIIVELDTPKHLDTETFFRNIKKLDDAKIDAVTLADNSLA
TVRISNVAAASIIKQRYDIEPLVHITCRDRNLIGLQSHLLGLSLLDINEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKTKTNFNIAGAFDPNVRKLDGAVRR
LEKKLESGMHYFITQPVYSKEKIKEVYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEDILEQFEAVKDDKAKTKALSLKLSKDLIDTVHEYFNGLYLITPFQKVDYTLELANY
SKTITSTKQEAIL
>A0A7V5VEC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldithrix abyssi|TrEMBL
SLLKLVDDLARYNPPFIDITSHAAEVIYEETPEGIKRKTKRKRPGTLGICALIQKKYNID
AVPHILCRGFTREETEDFLIDLQYLEIKNVLAVQGDDSGYKKPVPDGRTTNKYASDLVRQ
VKEMNEGHYLEDNLLDAKPSNFCIGVGGYPEKHFSAPNLDTDIYYLKKKIEAGAEYIVTQ
MFFDNKVYFDFVDRCRAEGIDVPIIPGLKIITRKSNITSLPRTFHIDLPVELSRQILDAS
ADDVAEIGIEWTLKQARELMEHNVPSIHFYVMQNTTPINTLLDRLMP
>A0A6B8XHQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARQIHEATHSLFKHHSQVGAL
>A0A1V0H9S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQELAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKDQAPQFDIIGACYPEGHPDSANQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARQIHEATHSLFKHHSQVGAL
>A0A5J6WXX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas simiae|TrEMBL
MGFHSARQVEALNQSIADLSGDISVSFEFFPPNSESMEQTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGVDKPEMYGADLVALLKAEADFDISVAAYPEVHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKVPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKQA
>T2IUW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocosphaera watsonii WH 0005|TrEMBL
MINHFRQAVQNKEFLITAEVAPPKGGNPTRMLEMAKQLKGRVHGVNITDGSRAVLRMSSM
AASALLLQYGIEPICQMTCRDRNAIALQADLMGAYALGLRNVLALTGDPIKAGDHKRSKP
VFEVESVRLLKMIDKLNEGIDFNDKTLADEPLDLFPGAAVDPQSRSWSGLQKRFERKVAA
GAQFFQSQLITDFEKLDKFMHQIAANSDKPILAGIFLFKSAKNAQFINNNVPGVEIPESI
IKRLGEAEEPLKEGIKIAAEQVKQAQKLCQGVHLMAVKREDLIPEILDQAGIPPMVSQ
>A0A5B7X0N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Antarcticibacterium flavum|TrEMBL
MKITEHIEAANGKTLFSFEILPPLKGQNIQSIFDGIDPLMEFKPPFIDVTYHREEYVYIE
QKNGLLEKKIVRKRPGTVGICAAIQSKYKVDAVPHILCGGFSKEDTENFLIDLDFLGIKN
VMALRGDAVKSETYFRPEPNGNFFASDLVRQIAGMNLGDFQEEILDNSHNTDFCIGVAGY
PEKHMEAPNLDQDIKRLKEKMAAGAEYVVTQMFFDNKKFFEFVDRCREQGITIPIIPGLK
PIATKKQLSVIPHRFHVDLPEELIHEVEKCRDNEQVRQVGVEWCTEQSRELIAAGVPVLH
YYSMGKSSNIKQIAGEVF
>A0A7S2URK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Attheya septentrionalis|TrEMBL
YCTMENESLAARLLNPSRPVFLLGDVPPGEGTPPGKCQTICNKFMARSRALASDGFIVYD
IQDEPGRSDMERPFPFRRVMDSSRYAALLARSSGKECVVYKCVADPNFDDWLQSASTEHG
HSAINLVGRASSQGEYQGPTISQAMEKVTATKTVQFGCVCIAERHTLEAAEARGKSYPTE
HQNMVRKQKAGCQWFISQAVYDSEPTIRLLKDYAALCREQGIIPRKVLLTFAPVSRKKTM
NFIKWLGVKVPPEVEAKILDAEKPVDASVALLCDTLRTILSECAGIGVPLGISCESVSIF
KAEIDGVHTLFGKLQEILLDAQGSPWKVQWVEIMPPLGPLVVKKTTKDISDNTAVTEQPT
QLVTQSSIAKDVVNNVSLLNAVMLGGMLVALGAVIGDH
>A0A3M4W3N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cichorii|TrEMBL
MPLEVPSTMSQDRRFSFEFFPTKTDAGHEKLLTVARQLASYNPDFFSCTYGAGGSTRDRT
INTVLQLENEVKIPAAPHLSCVGDSKAELRELLTQYKNAGIKRIVALRGDLPSGMGMASG
ELRYASDLVSFIREETGDHFHIEVAAYPEMHPQAHNFENDLKNFVHKSNAGADSAITQYF
FNADSYFHFVDRVQKQGVNLPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDD
IQSIQAFGEQVITEMCERLLEGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>R9VIH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida H8234|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSTERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALAAFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQLARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQPTPLPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAEAAQSK
VFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQTQVHTLEQWAPA
WQASWQMPGLPAVIFHPPQAAWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRRPLWATRVGAQVLHKVERAVKRPWVGCDTCGRCRLEDTLYVCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFQAATP
RRVSPQPAPRSQPES
>A0A0H3DXH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edwardsiella tarda (strain FL6-60)|TrEMBL
MSFFHASQHDALNQSLAELQGRIQVSFEFFPPRSQEMEQTLWRSIDRLSTLRPSFISVTY
GANSGERDRTHGVIKGIKERTGLEAAPHLTCVDVSREALRGIARDYWNSGIRHIVALRGD
LPAEGGRPEMYASDLVALLREEADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGASRA
ITQFFFDVESYLRFRDRCAAAGIDAEIVPGILPVSNFRQLQRFAALTNVRVPQWMLAMFD
GLDADAETRKLVGANIAMDMVKLLSREGVKDFHFYTLNRAELSYAICHTLGVRPQGSVA
>A0A195EIR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trachymyrmex cornetzi|TrEMBL
MRNLILENDMCERNDADGNDNPSTSDVHIENPRKTVVDLRQLLKDKISKNEIFCSFEIVS
TRKSGAFYQRLLINMEEYSPLFYALTWHNEAASDNDGYLPLDLAENFPANTLLHLAAKDS
LSENGDFEHAADLVVFIRQRFGDTFCVCVAGYPQMHPESPSKELDLHYLKAKVQAGADFI
ITQICFDSRVLINFVRDCREIGIQIPILPGILAPTNHACLEKMIDICRLDVPIKIKEDLA
RMKDDDQAARTYSVDLIAQIITDVIRNGATYGFHLFTLNRLSLVAEICKRIESFKAENL
>A0A7W8LNY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus budaensis|TrEMBL
MTRVSIELVPRSRSGLRAELEVVAQHLPGVDTVNVPDLSRFSTRSWQGCAFARPRYRAIP
HIRAVDLNPQAPLPMAETLAASGIDEVLIITGDAPADMSAKVYDVDAVRAIRRFRQELPH
IRVYAGLDPYRQSFARERDYLERKLDAGACGFFTQPFFDLRLMDAYADLVPAGVEVWWGA
TTVTTDATLNYWRARNHAVFPRAFAPTLEWNRAFAAQALAFARGRGQHVYFMPVKADTRA
YLEGIV
>A0A7W7RSJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium album|TrEMBL
MPCWRLPGLSGETGAAAGACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTAGGRT
SDLNVRAMIEEVRAASQEAAFAGTRPFRVGTATGLRPLPAWKRTADFVFVQVSFSMEALL
RWREATPVDVPVYAGVMVLASEAHARRLAAVIPDIDIPQKLVEKVSGDRDAGVEAACEQV
LRIRESGAFDGIHLIPVARYREVAARLESVLA
>A0A8H4JG93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium acutatum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCLGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAITVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLRAKLTSPELQDSVCFYASNARGDYLSSDSSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A6A6K1Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hevea brasiliensis|TrEMBL
MATTLALLSLVIQVLKAILGFLLCPILLHYPQKIISLCSSVIFRSEAHPDMIRSDGVATP
ENYQKDLEYLKRKVDAGADLIITQLFYDTDIFPELVNDCRQIGINCPIVPGIMPINNYKG
FLRMTGFCKTKVCIPPYRANRPKSYISRTLSWEQYPHDRWEDSCNPSYRALADYQFMRAR
ARDKKLHDEWATPLNSIEDILEKFKKHCLGKLKSSPWSELDGLQPETKIINEQLGKINLK
GFLTINSQPAVNGERSDSPSVGGTLVSNVGTNDVNVVTWGVFPAKQIIQPTVVDPASFNV
WKDEAFEIWSRGWASLYPEDDPSRKLLEGVQSGYFLVSLVDNDYIHGDIFAVFADL
>A0A6I0C3P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GXM4|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETADHFHIEVAAYPEMHPQARNYEDDLANFVRKAKAGADSAITQYFFNADSYFY
FVDRLQALGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTRSIQSFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A0C5FP04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cyaneogriseus subsp. noncyanogenus|TrEMBL
MRDILAAGKTTYSFEFSAPKTPKGQKNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVNE
TQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWVPHP
RGLTYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFF
QPESYLRLRDKVAAAGCETPIIPEVMPVTSVKMLERLPKLSNASFPEELKERILAVQDDP
AAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPQD
>A0A2D8LY33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micavibrio sp|TrEMBL
MTTFSFEYFPAKTDKGDMRLLDTAASLADKKPSFMTVTYGAGGSTKDGTLATVTRLQNET
GIPMAAHVTFINTEIPQLKDFADELWNSGIKRLVALRGDLPDDLSWPLDLEGNYFQYTSE
FVAALKSWHDFDISVGAYPEKHPDAPSLAADVKALRLKCVAGADRAITQFFFDNSVYYNF
LDECEKAHIKTPIVPGLLPIHDFKSMLSFAKKCRATVPGEIRAKFEEVENDTEGAKNLAR
DLLCAQVEDLAKQGCPHIHFYTLNKSDIVDMACQSLSPAV
>A0A3M3T9L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cichorii|TrEMBL
MPLEAPSIMSQDRRFSFEFFPTKTDAGHEKLLTVARQLASYNPDFFSCTYGAGGSTRDRT
INTVLQLENEVRIPAAPHLSCVGDSKAELRELLTQYKNAGIKRIVALRGDLPSGMGMASG
ELRYASDLVSFIREETGSHFHIEVAAYPEMHPQAHNFESDLKNFVHKANAGADSAITQYF
FNADSYFHFVERVQKKGVNLPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDD
IQSIQAFGEQVITEMCERLLEGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0B1ZTH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium malaysiense|TrEMBL
MTAAPRPAEMPLFGELPGDISVSFEFFPPKTEKMEAQLWDAITQLAPLAPKFVSVTYGAG
GSTRERTHATVSRLVRKTDLVPAAHLTCVGASRGEIDEIVDQYWEAGVRHIVALRGDPPP
TDEGVFKPHPEGYTCAADLVAGLKARHDFDISVAAYPEIHPEALSPEADLDNLKRKIDAG
ASRAITQFFFSTDAYFRFMDKALAAGIDAPIIPGIMPVTSFAAIRRMSGNTQIPDWLEAM
FEGLDERPGPRALVAAVAAADLCKRLYDGGVRDYHFYTLNKAEQTYAICQLLGLRPQTKP
TETAA
>A0A0M3G0S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus haemolyticus|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERGRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWESGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIESYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPE
>A0A024YKL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PCS3-D2|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMAEWVAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVAKAGCDTPIIPEVMPVVGIKQLDRLPQLSTAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A1M5BV23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofundulus australicus DSM 11792|TrEMBL
MKTESKLQKLLDSGHFAVTAEIGPPKHASAHGIRHHAQMLKDYVDATNITDCQTAIVRLS
SIASAVHILDCGLEPIVQMTCRDRNRIAIQSDLLGAYSLGVRNLLCLSGDHQKFGNEPSA
KNVYDIDSIQLIYLMRRMRDEKLFFSGEPIKEHEPRFFIGAVANPFADPFEFRVARLEKK
VEAGAEFIQTQCIFDMERFERFMEMVRERGIHERVHILAGVTPLKSWRAAKYLQTSVSGM
IVPDDIVERLKKADDPKREGIEICIEQIKHIRTIPGVHGVHIMAIAWEEVVPEIVERSGL
YPRPKVE
>A0A2H1JKE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium linens|TrEMBL
MSQSTLRTLLSTARYEVLPTAGIVERIEEYVAPGREITVTASTGLTLEATLATAEQLQAL
GFRAVPHLAARMIHGRPELTEIVDRLAEAAVDRIFVPAGDATPPAGGYVGAHDLLVDLSS
MAAPFRHIGVSAYPESHPIIPDDVTVQAMWDKRDYATHLVSNLCFDPALVAAWVARVRSR
GIELPLVIGIAGKVELAKLARVATKIGVGESTRFLRKNTATFTRMAKPGGYNPRKFLDKI
GPVLDDPDMGIAGLHIYTFNQIKDTEVWRRKQLAALGGAEEVSTAW
>A0A0M1J4L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromatium sp. WMS2|TrEMBL
MINNKYNAMTFSFELFPPKTAEGLEKLKPQIAALTAVKPKYFSVTYGAGGSTRERTFATV
DWLRSQGIDTAPHLSCIGSSRQEIKDILIHYQNQDIHRLVALRGDLPSGMGSSESGDFRY
ANELVAFIRSEMGDHFHIEVAAYPEIHPQASNAVKDLHNFQTKVAAGANSAITQYFYNLD
AYTKFRDDCHKLGIDIPIIPGIMPITNYKQLTRFSDACGAEIPRWIRKRLETYQDNPESL
QVFGHEVVTNLCRQLLDSGAPGLHFYTMNQATYPLNIWQELGL
>A0A7U3Y1I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain ACICU)|TrEMBL
MFRCLQGFDMTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRER
TLAAIEDFNGKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGE
LPYAQDLVRFIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFF
NPDSYFYFIERLDKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDS
ESIKAFGHEVVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A1F8L4Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium GWB2_54_36|TrEMBL
METRTKFLEKIQADRPLISDGAMGTLLHQRGVSFDQSFDELNLTSPALVADIHREYIDAG
SNIIQTNTFGANRYKLAQHGLEKRVSEINTNAVELARRVVLASYKDVLIAGDVGPLGVRL
APFGRVQPEEARIVFREQIDALISANVDLLIIETMTDLYELREAILAARDINSDIPVVAS
MTFTRDDRTLLGDDPAKVARKLREAGADVIGVNCSGGPNQILRILKQMVQAVPQGKFSVM
PNAGWPEQVAGRIMYPASPEYFADYALAFWHAGACLIGGCCGTTPKHIAVMHQAIENAPS
GSAPNGFTLTAVEREEAAPEGMQPTQLAEKLANGQFVFAVEVDPPRGLTAQKLMAGSSLL
KEAGADVINVADSPMARMRMSPWAVCRLIQEKVGMETVLHFPTRGRNLLRVQGDLLAAHA
LGVRNVFVVMGDPTAIGDYPDAMDNYDLVPSGLIKLIKQGFNTGVDHAGADIGQPTSFFA
GCALNLTAADPDNEIKNLRRKLRAGADFILTQPIYDPPAAKAFIERAAEELGGLKVPVLI
GLLPLVSARHAAFLQHEVPGIEIPDDVQSRMTLSGEREARTGIEIAIELIHQIKQFAQGI
YLMPAFNRFDYAAEIIETIREGN
>A0A1Q2L4R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus lenghuensis|TrEMBL
MGLLEELKTKILTADGAMGTLLYSNGIEYCNEELNLERPEIIERIHREYIQAGADIIQTN
TYGGNALKLARYGLEHQVKEINRAAIQIAKRAAAPGGQYVFGTIGGIRGIRKSDASLQEI
IAMVNQQAGYLLGDDPDALLLETYYDFEELAATVSYLKKLTDTPIIAQVSMHEPGILQNG
MSLNDALQQLEALGADIVGVNCRLGPHHSIQALEEVVLPSKAFLSAYPNASLLDVEDGRV
VYEPEADYFGRTALLLREEGVRLIGGCCGTTPKHIEAVKKRIGNLAPVTQKEVVAKKPIV
IREAEALEVKPLHEKAKTERTIIVELDTPRHLDISKFIEGSKALDKMGVDAVTMADNSLA
SPRISNMAMGSILKHQENIRPLAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVKR
LEKKIESGADYFISQPVYTKEKIIEIHEETKHLETPIFIGVMPLTSIRSAEFLHNEVPGI
KLSEDALERMRACGEDKDRATAEGIQIAKELIDTAAELFHGIYLITPFFRYDMSVELIRY
IRQLDSQKESESSYVQASY
>A0A5B9TNI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurospirillum multivorans|TrEMBL
MIENFIEKLKHDTFLTLETTPMHEPTFEPIIEKIATFGLDKIVDGFSTTDNPLARLKFNA
LFGALKLQTQFHKPVIATMSMRDRNKVALQSDLLGANGFDLRTILALTGDPASASDQPAV
KGVFEGNSTLLLEIIQCFNAGIDYSGKPFKTQPKPIYSFAVCNAHANTPKNLMKKMATKI
KHGAVGIITQPVYSVENAKMLLDLLKDAKAEINKEQSQAQLILGFFPIIKLRTAQFLSAH
VPGIHVPSIWMDKLAHAKKISEEEEKKVGFELSLNAFLELKKIHPKIHIMSANNFELVAD
LVKY
>A0A6M7VQ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. NZP2234|TrEMBL
MTARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A4Q7E8W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomicronema excentricum str. Lakshadweep|TrEMBL
MSPTDTHTLPTSHFQKAAEAREFLITAEVMPPKGGDVSHMVKMAQQLRGRVHAVNITDGS
RAVMRMSSLAASVILRQQGLEPICQMACRDRNRIALQADLLGAYALGIRNILALTGDPVK
AGDQTGARPVFDLESVRLLQLIRQLNNGVDACDRPLPNQAVRLFAGAAIDPQCRSWSGLQ
RRFAKKLEAGAQFFQSQLIDDFERLEKFMDQIAAGCDKPILAGIFLLKSAKNAQFINRNV
PGVNIPEHIIQRLATASDPLREGMLIAAEQVKAAQQLCQGVHMMAIRREDLIPEILDLAG
ISPLQTVPTVLQREPAELARVRFSRTKVLGGEG
>F0BCJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas vesicatoria ATCC 35937|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTATKLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAVDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
ASLCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1I7JQW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax caeni|TrEMBL
MSLPISFEFFPPKTPEGAEKLRAVRQQLYALRPQFCSVTYGAGGSTQEGTFATVCAILGE
GMDAASHFSCIGATRAGVRAQLAELKAMGVKRLVALRGDLPSGYGIGGEFHYASDLVAFI
RAETGRDFHIEVAAYPEVHPQARSPEADLQAFAAKVRAGADSAITQYFFNADAYSRFVDD
VRRLGLDVPVVPGIMPIMGSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIRAFGMDVV
AQLCEQLRRAGAPGLHFYTMNQSATTQALCQRLGLIG
>A0A653NFX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter litoralis|TrEMBL
MKVTDHITNAQGKTLFSFEIVPPVKGRNIQELYNNIDPLMEFNPPFIDVTTSREETIYIK
KEGLLDKKTTRMRPGTVGICASIQHKYNVDTVPHVLCGGFTKEETEYMLVDCHYLGIENV
MALRGDARSEQKYFEPTDGGHPFAIDLVKQIQDLNCGKYLHETIESEYSSEFCIGVAGYP
EKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEAAKEMGINVPIIPGIKP
LAVKRHLQLLPQVFRIDLPQDLIDAVDGCATNKDVRKVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAEALF
>A0A329Y5Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium tropici|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMG
VQNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLHEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRTDALVAERLHQISEGREENQQAMAEIAA
HHTPPQAH
>A0A0F3FSF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium baratii|TrEMBL
MNIRELFDNKRLVLSFEVFPPKNTSPVKTIYKALNELSTLKPDFISVTYGAGGSLINNKT
SEISSLIKNVYNIEALAHLTCISSKKENIDDITERLELEGIRNILALRGDNNDNEAGDYK
YATDLIKYINKKDKFNIISACYPEGHIENKGIEAEIMNMKRKIESGTSSFISQLFFDNNI
YYDFLDKAKGNGVNVPIQAGIMPVVNKKQIDRITSLCGATIPLKFKKIMEKYEYDSEALR
EAGIAYAIEQIIDLASSGVDGIHLYTMNNPYVARRIKENIEVIVKSINNKGETIA
>I4NAU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. M47T1|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLNVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKADLRGLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIRAETGSHFHIEVAAYPEMHPQAHNFEDDIKNFVRKANAGADSAITQYFFNADSYFY
FVERVQKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVGSIQTFG
EEVITRMCEQLLDGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A432TBE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp|TrEMBL
MFEKFCKTLHSNNSPFITIEITPPHGASIKPIIEKIKKLKLYEKVAGFSVTDNPLAKLKM
SGVLSAIQVQDAFGKPVITTMSMRDKNKLSLQSTLLGANDFNLRCILALTGDPAKFSDQP
EVKGVLERDSTLLLSIIYKLNNGFSYSNKELNPKPNPIYPFAVSNAYAKDMKHIKKKILK
KLNYGARGIITQPVYDLENAKELLEIFEECKYESVRDTAKDAELILGQFPVVRAKTANFI
SDKVPGITVPKGIIDEMNLAAMDGEEQEQKIGFEISKTLFDDILKLHPKIHLMTHNHFDL
CSSLIGDGN
>A0A348G1R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastochloris tepida|TrEMBL
MTLSSCRPSRFVGGPGISVSFEFFPPKTAEMDAQLWESITRLAPLNPAFVSVTYGAGGST
RERTHAIVKRIVEETALKPAAHLTCVAATREEIDAVIHAYWAAGVRHIVALRGDPPAGPG
TVYEPHPGGYAHSTDLVAGIKRIADFEVSVSAYPEKHPESASIEADLDVLKAKVEAGASR
AISQFFFDNAHFLRYRDRVAARGLHIPIVPGILPVMNFKQAKSFAERCGTEVPGWLARRF
EGLDNDLRTRELIAAAVAAEQVLDLVDHGVTEFHFYTMNRADLVYAICHLLGLRPVAAQA
AA
>A0A1Z9TI85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium TMED261|TrEMBL
MKKISRQVSEIHTEFSFELFPPKSEIGEKNLLSQIHLVERIKTRAICVTSGAGGSGNDRT
LKTIKSLENNVSSNLTAHLTCIAATKNQTHQSLDRYAQEGIFNIVALRGDLNEDQNDLTT
LDSYGNAANLVRGIRNRNDGDQFHISVAGYPETHPKAKSRKSDLENLKEKVDEGADLILT
QFFFDPVTFFQFIEDTDRVGISVPIIPGLVIPSNFHRVFNFAEKCGTHIPDSLVKKFDGV
ESGSETANRIATEITLQQCSHLSENDIRSFHFYTLNRLDLVVPVCELLQEGISSSPKPVH
RKP
>A0A239AWJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas japonica|TrEMBL
MTQERRYSFEFFPTKTDAGHEKLLATARTLASYKPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKAELRALLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIREETADQFHIEIAAYPEMHPQARNFEDDLANFVRKANAGADSAITQYFFNAESYFY
FVERVQKLGVKIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EEVITQMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1H4D7J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax soli|TrEMBL
MTAANAPATGLPVSFEFFPPKTPEGAEKLRTVRQQLYASKPEFCSVTYGAGGSTQEGTFG
TVQEILAEGVSAASHFSCVGATRQSVREQLATLKSMGVRRLVALRGDLPSGYGMGGEFHY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPEADLQAFAAKVHAGADSAITQYFFNAD
AYERFVNDVRRLGLDVPVVPGIMPIMGSSQLMRFSDACGAEIPRWIRLRLQGFGDDTASI
RAFGLDVVASLCEQLRQRGVPGLHFYTMNQSATTLELCRRLGL
>A0A329YB56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium tropici|TrEMBL
MSSRSESLSDGIRISFEFFPPKSEEAEQQLWATVADLSDWEPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLAAGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVGALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKAENGADRALTQF
FFDNDAFERYHDRVRAAGIRIPVVPGIMPIQNLTQLKRFAGACGASIPSWLDDRFDGLDE
NVEERAKVAADVAAEQIQDLIRRGIHEFHLYTMNRSALVSAVLERLGLQRKLDARAGAAA
>A0A2K9PSR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavivirga eckloniae|TrEMBL
MLRDKIVNKKSGILLYGLTPPKLNIDKSKIQLIANKLIERVKHLPIDGLVLYDIQDESAR
TNQVRPFPFNETLTPDDYSNNYLGELKIPKIIYKSVGKYTANEFKNWIDENSNTIDYSVF
VGTPSDELVLNLPLNDAYKINRDAKHSIPLGGVTIPERHYQLNDEHLRIFGKIDKGCKFF
ISQCIYNTYNTKNFLSDYHYYSIENNKELQPIIFTLTPCGSLKSLEFMEWLGIDFPKWLK
NEFKYSKDMLVKSIDTCKYIARELIDYSNEKNIPIGFNIESVSVRKEDVEASVELLKDVK
VLMNEYEYESLSLSGNIMEE
>A0A1D2L884|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brochothrix thermosphacta|TrEMBL
MTNLRDSLKNNVLIADGAIGTLLKQHDHTHGHGPSIDALNLSQPDQIRDYHLAYLRAGAD
VIQTNTYGANTLKLARYGLEKDIVAINQAGVRLAKEAIKIHGRGFLLGNIGGINAEYVPV
HLRSTSLDDIQKVFREQLYLLLLEGVDGLLLETYYDLEELKTVLKIAREVTDIPIIANVS
IHEVGILQNGTRLDIALQELADLGADVVGVNCQLGPYHMIKALEGVPILTNASLAVYPNA
SLPTVEDGEIIYQTEPSYFKKYAERFRLQGAHLIGGCCGTTPAHIANLRKGLESTTPVDT
KVVIPLPDEVVFTKPKKFRGKRLVDKVLTETTVLVELDPPRTLNTETFFKGVQALYNQGT
DAVTISDNSLASPRISNLALAALIKERYNHSPLIHITTRDHNLVGLHAHVMGLHKLGIHD
LLAITGDPTKVGDFPGASSVFDLRSVELVQLIKRYNDGLSYSGKSLGEKANFNVAAAFNP
NIKKLQQAYKIIQRKIDYGADYFITQPVYDVETVHQLADMLNEHNITTPFFIGVMPLLSS
RNAEFLHNEVPGIRLSDEVRDRMKQADLDNRSLEVGLEISKEIIDAILERFNGIYIITPF
QRYEVSLELLHYAKKTAPILK
>G1PJ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myotis lucifugus|TrEMBL
MDHLKPEVLPARHCCPSLGMRALEAGLMRFSVPPSISRNSAMVNEPRGNGSPNPCLEGSS
SGMESPKDSSRCSSPGLDPERHERLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISGF
DQMGAGGPLFIDVTWHSAGEPGSDKETSSMAIASAAVNYCGLETVLHMTCCRQSQEEITG
HLHKAKRLGLKNILALRGDPVGDQWEEEEGCFCYATDLVKLIRSEFGDYFDICVAGYPKG
HPDAESFEDDLQHLKEKVSAGADFIITQLFFEADTFFHFVKACSAIGITCPILPGIFPIQ
QGYHSLRQLVKLSKLEVPQKIRDVIEPIKDNDEAIRNYGIDQAVSLCQELLASGLVPGLH
FYTLNRSMATTKVLKRLGMWAEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQ
DWDEFPNGRWGHSSSPAFGELKDYYLFYLTSKAPREELLKMWGEELTSEESVFEVFVHYL
SGEPNQSGCRVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVG
WGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYEQRVNYHIVDVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWVKQWGKLYDEESPRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPGARGDRLRDP
>A0A7G3G5I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Iodobacter fluviatilis|TrEMBL
MTPSPISFEFFPPRTAEGAEKLRNTRRQLAQFKPEFFSVTFGAGGTTQEGTLNAVLDIQS
EGHAAAPHLSCVGSSKENIRSIVQNYKDHGIRHIVALRGDIPSGMGDFGEFRYANELVSF
LRQEFGDWFHIEVAAYPEFHPQAQSAEADIRNFVNKVRAGADSAITQYFFNADAYFRFVD
EINARGISIPIVPGIMPIQNFSQLARFSEMCGAEIPRWLRLRLQAFGDDTASIRAFGLDF
VTELSDRVLAGGAPGLHFYTLNAAGAVSTVCQRLGR
>I9AXF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelosinus fermentans B4|TrEMBL
MKLSDRFNKGKTLVSFEIFPPKQTVTLESIFKTTEGLQTLNPDFTSITYGAGGSASDRTI
ETADKIKNTYGVEALAHLTCINSHKDDIDLMLNQLQAHNIENILAMRGDYPINKNNDKGR
ENTYQYAKDLIAHIKSNHDFCIAAAAYPEGHPECPDLNTDLLHLKEKVNSGTDFLITQMF
FDNAIFYDFLDRIKQVNITIPVSAGIMPLLNSKQVGRIKGLCGASIPKPLQNIIEKYEHS
SLDFEKAGIEYACSQITDLVANQVDGIHLYTMNKLEQSKTIIQQTNLR
>A0A1F9E927|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFCSPHIGHO2_02_FULL_38_15|TrEMBL
MSTFQERLSKNEFVITAEVCPPKGPDTKEFLEKALLLKDHVHAFNVTDNQRSVMRFSALV
SSHLLVQAGLEPIFQISCRDRNSLALESDLLGASRLGIQNLLPLTGDPIRAGDHQLAKGV
FEFESVKLLQTIKKMNNGFDFYDNPIDGKTNFFAGAVVNPTAPNINTHLKRMEKKIEAGA
KFFQTQAVFDLKAFEVFMKEAQKFNTKIIAGILLIRSHKNVNYLRHHVPGLNIPEALKQE
LKDSSNPMQTGVEIAARQIKSLQGLCHGVHLMAIKYEEKIVDILNHVKTL
>A0A2S2DVZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquirufa nivalisilvae|TrEMBL
MTKITEYFKNSGGKTLFSIEIIPPVKGQHLGELMGHIEPLMEFKPPFIEVTYHREEFIEK
EVNGELKRIPIRKRPGTLGICAALMQKFKVEAVPHVICGGFTQEETEDFLIDLHYLGIEN
VLALRGDQEKGEDRFIPKLGGHAYANELVEQICRMNKGQLLYEETESFPTNFCVGVAAYP
EKHFEAVSLETDLQYLKQKVDAGADYVVTQMFFDNQKYFDFVKACRAIGINVPIIPGIKP
LATVKQLEVLPAIFHLEIPNDLSKAVLAATNSAGIKQAGIEWAIQQGKELIQAGVPALHF
YTMSKSDSVRSIASALF
>C0N2W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga thiooxydans DMS010|TrEMBL
MGWFLSAHFFNKSKKNMSNNLTISCEFFPPKTEKGIANLRRVREELRPLAPEFYSVTFGA
GGSTQDNTLEAVIDIQKQQPETDIDAAPHLSCVGSNADRLRTILNTYRDNNIRRVVALRG
DLPSGMRDPGDFRYANELVEFIRNETGDFFNIEVAAYPEVHPQAPTAELDLENFKRKVDA
GADSAITQYFYNIDAYRFFLDRCEKLGIDIPIIPGIMPINNFAQLSRFSAGCGAEIPRWL
RKRLEEFYDDTESMQAFTLDFLTEFTQQLIDIGVPGLHFYSMNKTQPTLTVCERLGLVKT
>A0A180GTG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia triticina (isolate 1-1 / race 1 (BBBD))|TrEMBL
MKISQKLAAENRISWSFEYFPPKTDNGLTNLYDRIYRMSQLGPIFIDITWGAGGSTSNLT
TEFVKTAHEQFGLETCMHLTCTNMPKERIDTALREAYEFGCENILALRGDPPKGSSEWTA
TEGGFEHAIDLVRHIRAQYGDHFDIAVAGFPEGHMHSSLSREQETIYLKEKIDAGANFIF
TQMFYDVDIFIDWVREIRAAGITVPVIPGLMPIQSWAQFKRVTNFSKTIVPQYFLDKLEP
IQSDDQAVREAGTKLVADMCRKILNSDLGIRILHFYTMNLERGTKMILDELNLNPSRDIT
NPLPWKMSLLGKRRSESIRPIFWANRAKSYLSRTETWDEFPNGRWGDSRSPAYGELDGYG
ININSATIETLKGLKKFPTSLEDLARIFANYCGARFPGEEPVKYLPWSDIPLSEETNKIE
DVLVKINKRGFLTINSQPAVDGAKSSDPVHGWGPRGGYVYQKAYLEFFCCPEKFQSLTER
LEKDPDVTYYAVTKTGDLVTNNTRPGPNAVTWGVFPGKEIVQPTIVELVSFIAWKDEAFE
LGHQWAELYKELAPESSQFIHEIMDSWYLVNIVNNDFRKSNDDSDDSALFQFFGPEPVIV
KEDNVPSTNGVHHTNGIAKVNGSSTPAVSEVNGDLKNLAI
>A0A2W7RGJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrotalea sandarakina|TrEMBL
MKVTEHIQQAKSTLLSFEVLPPLKGKTITSIYDHLDPLMEFKPSWINVTYHRSETMFKKK
ADGSFEKVEVRKRPGTVGICAALMNHYQIDTVPHLICGGFTKRESEDALIDLNFLGIDNV
LVLRGDAAKNEAGFEPEPNGHAHAIDLQKQVVNLNHGIYIDEDIRDGGKTNFCIGTAGYP
EKHFEAPNLEIDLQFLKEKVDAGADYIMTQMFFDNQKFFAFEKACRDLGIQVPIIPGLKP
ITTKKQLTVLPRIFHVDIPTDLSNAILKCKTDAEVEAIGTEWLIQQSKELKSHGVPVLHY
YTLGKPKVIRNVVKEVF
>A0A5B0WVJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudohalioglobus sp. NY5|TrEMBL
MAKPRISFEFFPPKTPAGKDKLLNETTPALNALGPEFFSVTYGAGGATRDTTLGVVSAIR
ETGIDVAPHLSFGGDDEETVAQLLETYKARGITRLVALRGDMPSGMGAAMQLVYANELVD
FIRQRTGDHFQIHVAAYPEIHPESRSYQSDVEFLKRKLDAGANSAITQYFYNVEAYFYFL
DQCAAMGIDKPVYAGIMPITNFQNLARFSRNCGAEIPRWICKRMEDFGDDQESVRQFGLE
VVTQLCQTLIESGCPGIHFYTMNQVEPTRQIYNNLGL
>A0A5C9D7D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystaceae bacterium|TrEMBL
MFNALHPTASPNQFAISYEFFPPKTPEMETQLWQTINRLAALRPHFVSVTYGAGGTTRER
THSIVARIVRETEMKPAAHLTCVSAAREDIDAILRDYWDAGVRHIVALRGDPPTGVGSRF
EAHPKGYAHSTDLVSGIRRIGDFEISVSTYPEGHPESASIEQDLDALQAKVDAGATRAIT
QFFFDNDVYFKFLDKARGRGITIPIVPGIMPIRNFKQVAGFAQKAGASVPRWLAERFDGL
DEDPETRALIAATTAVEQVMSLARAGVNEFHFYTNNRADLVFAICHLLGVRPLREKALA
>A0A4P6X0W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga pseudoflava|TrEMBL
MGLPLSFEFFPPKTPEGAEKLRVVRQKLYALKPEFCSVTYGAGGSTQKGTFDTVQAILAE
GVDAASHFSCIGATKAGVREQLATLKAMGVRRLVALRGDLPSGYGLGGEFQHASDLVTFI
REETGRDFHIEVAAYPEIHPQAKSPEADLQAYVTKVKAGADSAITQYFYSADAYFRFVDE
ARRHGADVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQAFGDDTESIKAFGLDVV
TDLCDRLRSAGAPALHFYTMNQSVATLEIARRLAGQLPHH
>A0A1U7DAD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger profundus|TrEMBL
MALLNFRSAKPAKPTGTLGSLLSDYSIEVMPRTAAKVEDFRALLPRSTRVYIAHIDGTPI
DEMVATAKRISAEGFEVMPHFPARIIRDRATLADWIARYQGEAGVHQGLILAGGVPEPQG
DFHSSMQLLETGLFDKAGFDRLHVAGHPEGNRDIDPAGGEDTVMEAARWKQDFSERTDAE
MALVTQFAFEAEPVLAWGARLRDAGVTLPIHVGLAGPAKLQTLIKFAVACGVGPSLRVLQ
KRALDVSKLLLPYEPTDIATELAARKAADPAFPIEQVHLFPLGGIKSCAEWAATHGGTAT
LPAARAV
>C9RM26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter succinogenes (strain ATCC 19169 / S85)|TrEMBL
MKIIDILKQDKMSLSFEVFPPKKETSFENVKAATEAIAKLNPAFMSVTYGAGGGVSQYTL
EIAKNLKYNFNIPMLAHLTCISSTKETIHQRIEDMKAAGIKNVMALRGDLTPELIANGRG
DCDYHHAVELIRELKAADADFCIGAACYPEKHPESPNQAEDIKHLKEKVEAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQHFKSLVDKFGS
DPEAMKQAGIIYATDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFAG
>A0A6L6GSW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia sp. J316|TrEMBL
MSFFHANQREALNQSLAEISGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPGWMTSMFE
GLDNDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPEASVAV
>A0A1F9US48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_59_12|TrEMBL
MKISQMLAAKKPLFSFEFFPPKDDASTEVLMDVARSLRDLRPDFVSVTYGAGGNTRARTL
DLVTRIKRDIGIEAAAHLTCVGHSRQEIRTILDELALKGIENIIALRGDPPRGQMEFKPH
PDGFRYANELAGEVARSARFCFAVAGYPEKHMEAPSLEADLDHLKLKVDAGASWVITQLF
FLNDRYFEFVNRARAIGIRCPIIPGIMPITNFAQVQRFATLCGATLPRALAQELEPVQAD
PEAVARVGIRHAAAQCRELLQKGAPGIHFYTLNKSRATREILEHLRGLRDTTAPLLRDI
>A0A4R6YWB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas brenneri|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCETLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A0A0HF83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius mucosus DSM 17069|TrEMBL
MALFNFKKREKFTPANGQLEAFLDGYSIEVMPRTAEKVENFRDLLPAGTRVYIAHIEGTP
IEDMVATAARLNAEGYPVMPHFPARIIKDRATLADWIARYQGEANVDQALLLAGGVTTPH
GDFDSSMQLLESGEFDRAGFERLHVAGHPEGNKDIDPDGSMKNVEDALRWKQKFSETTDA
KMALATQFAFDAKPIIAWADSLSAAGITLPIHIGIAGPAKLQTLIKFAIACGVGPSLKVL
QKRAMDVSKLLLPYEPTEVLSELAAHKAANQNFNIEHVHFFPLGGIKANAEWAIENGGAS
ATPANQQG
>A0A0X8GRN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. B9-8|TrEMBL
MTPSPISFEFFPPRTPEGAEKLRTTRRQLAQFKPEFFSVTFGAGGTTQEGTLNAVLDIQS
EGHAAAPHLSCVGSSKESIRSIVQNYKDHGIRHIVALRGDIPSGMGDFGEFRYANELVSF
LRDEFGDWFHIEVAAYPEFHPQAQSAEADIRNFVNKVRAGANSAITQYFFNADAYFRFVD
EVNARGVTIPIVPGIMPIQNFSQLARFSDMCGAEIPRWLRLRLQAFGDDTASIRAFGLDF
VTELSDRVLAGGAPGLHFYTLNAAGAVSTVCQRLGR
>A0A6A7N197|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rugamonas aquatica|TrEMBL
MANHNFSIEFFPPKTAEGAEKLRVTRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILA
AGEDAAPHLSCVGGTRESIREILTEFKAHNIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGEWFHIEVAAYPEVHPQAKSPQDDLLAFERKVKAGANAAITQYFYNADAYFQFVE
QTRKMGIDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQAAATTALWQRLV
>A0A2S5R0Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp|TrEMBL
MNNNIPLSFEFFPPKTAEGIDKLRETRQQLAKFDPEFFSVTFGAGGSTRDRTMDTVLEIQ
AEGFSAAPHISCISSSKSEIRELLHAYQSHGIKRLVTLRGDVPSGEVSSGDFRYALELVE
FIRAETGNYFHIEVAAYPEFHPEARSPAADLLNLKRKVEAGANSAITQYFYNADAYFRFI
DQCATANINVPVVPGIMPIYNITQLARFSSVCGAEIPRWLKMRLEEYGDDLQSLRAFGID
VVSELCAHLLESGVPSLHFYTLNQAGIISNIIENIRAE
>A0A1J5HIK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium CG2_30_38_12|TrEMBL
MSVVNSILNNSKTAFSFELLPPLKGNGIDSVYRTIDALLDFDPKYINITTHRSEMAFKEM
PNGLFERVSERHRPGTVAIAAAIRNKYKIPVVPHIICSGFTREETEYALIDLQFLGISDV
LLLRGDKAKHEKEFAPTGHAHATELQQQVNRYNEGFFLDGSKMKTTTPAFSYGMACYPEK
HEEAPNLASDLHYAKQKVDAGAEYLVTQMFFDNKKYFDFVDKCHEIGIHVPIIPGLKPIT
FMNQLTVLPKIFHTDLPEEFVSELHACHSDADATEVGVEWCTLQAKDLISKGVPSIHFYS
MMATQSVKRIAQAVY
>A0A1G4QR29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asticcacaulis taihuensis|TrEMBL
MSPSLNPNLKSDLAPIARSLAAGGQNLKVSFEFFPPKTEEMETTLWESIRRLAPLNPEFV
SVTYGAGGSTRERTHRTVKRILDETHLKPAAHLTCVDASREEVDEVIRAYWEAGVRHIVS
LRGDPPSGFGDYKPRNDGYQNATELTAAIKRIGDFEVSVGVYPEKHPQSPSLAFDLDVLR
QKVDAGATRGISQFFFEPATFLRFRDAVADAGIKIDLTPGIMPVTNFKGLRRMAAACEAA
IPDWLGELFEGLDEDADTRKLLASAVAVELCLGLEREGVENFHFYTLNRADLVFAIGRIL
GLKAVSA
>A0A3S1C1S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichormus variabilis SAG 1403-4b|TrEMBL
MPDTHSSSAFNNFRKAALAGEFLITAEVAPPKGGNPTHTIEMAATLKGRVHAVNITDGSR
AVLGMSSLAASVILLQNGIEPICQVACRDRNRIGIQADLMGAHALGIRNILALTGDPVKA
GDHPDAKAVFDLEAVRLLQLIRKMNQGVDFNEKLLNDGALDLFAGAAVDPQSKSWSGLQS
RFEKKIEAGAQFFQSQLITDFERLEKFMDKIASSYNKPILAGIFLLKSAKNAQFINRMVP
GVNIPEHIIDRLAKAKQPLQEGMKIAAEQVQIARGLCQGVHLMAVKREDLIAPILDLAGV
GKVS
>G4FBK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. HAL1|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTREVVR
AVGESGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRTETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKVVDNLTD
>A0A066WNT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium seoulense|TrEMBL
MVVGLSYGFKPERKTTNNKQQTTKMKVTQHIENAKGKPLFSFEIVPPQKGSNIKDLYENI
DPLMDFKPPFIDVTTSREEYVYIEKDGLFDRRITRMRPGTVGICASIQHKYGVDAIPHVL
CGGFTKEETEYLLVDCHYLGIENLVALRGDPMKGEKYFEPMKGGNTYAVDLVRQIKAMNS
GKFLHGELPITNAPDFCVGVAGYPEKHIEAPSLEADLKRLKEKVDAGADYIVTQMFFDNQ
RYFKFVEAARAIGITVPIIPGIKPVAVKRHLQLLPQVFWLDMPESLINEIENAKDNAAVR
QIGVEFAVQQSKELMEFGVPCLHYYSMGKSDNIHQIASQLF
>A0A848LUF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyxidicoccus fallax|TrEMBL
MKIRNRLNPSNPCFSFEFFPPKTDEGVANLFKTLEDLAPLQPGFVSVTYGAGGSTRDRTV
ELVTRIKQETGIEAMAHLTCVGHTKDELRELLRRLQDAKLENVLALRGDPPQGQKEFVPE
PGGFRYASELVQFIREEDFNFSIGGACYPEGHVETLSRDDDLRHLKAKVDAGLDFVVTQL
FFDNAFFFDFVERARRAGINVPIVPGIMPITNYEQIQRFTRMCGATVPMRLALQLERVKD
QPDALVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRART
>A0A5H7SAI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Wentworth|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6A7SGM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|wastewater metagenome|TrEMBL
MTQPKNLDTRPAGLHLEVVPPVLRESEAGVEAALEKVATINEAVGLDAVNIPEIREESSK
SDKGERKRPFEPRMEPRVLARRIRDELGIESMINRVVVHLTREEQADWFRETWEEYGVRQ
FVLVGGEKSGVDYPGPSVPEANEMIRKAIAEPGLRVGNICIPTRDGEADRMRRKMATGVD
FFTTQIIYHAHEFTDLVDALVDNGLPETPPELLLTMCPVKGPRNIRFLHWLGVSISPELE
EWLVGDGEGVTDRSIEHIERTWQEISAHRARRAPGLPVGVSLAPIGKIPHETTIRLARAF
TGGVRARATA
>A0A6J1VV70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Notechis scutatus|TrEMBL
GYHSLRQLVKLSKLVVPQEIKDVIEPIKDNDAAIRNYGIELAIKMCRELLESGLVHGLHF
YTLNREVATMEILRRLGLWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSAREELLKMWGEELTCEQSVYEVFRCYIA
GEANRNGHKVTCLPWNDDPLAAETNLMKDELVKVNRRGILTINSQPNINGKPSTDPIVGW
GPEGGYVFQKAYLEFFTSAENIKALLTVLKKYGERVNYHIVNVKGENVTNAHEMQPNAVT
WGIFPGREIIQPTVVDPVSFMYWKDEAFTLWIEQWAKLYEEESPSRMIIQYIHDNYYLVN
LVDNDFPLESCLWQVLEDTYEQLNSPGEEAKTSGF
>A0A6G8I6C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp. DMV24BSW_D|TrEMBL
MSSSWALSLEFFPPRDENARGKLTAAAKELEVLNPAYVSVTFGAGGSTREGTADAVDLLQ
KLGYEAAPHLSCIGASRSVLGDILQYYKDQGVRRLVALRGDLPSGMGMNKGELHYAVDLV
RFIREQTGDWFHIEVAAYPEVHPQAKGAQADLNHFVEKVRAGANSAITQYFFTADAYYDF
VDRAREKGVGVPIVPGIMPITNHNQLVRFSDMCGAEVPRWIRQRLSDYGDDLASIRAFGA
EVVTRLCQDLLDQGAPGLHFYTLNNAGATLAIARRLT
>A0A1E1MVG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhynchosporium secalis|TrEMBL
MEKITDKIAALPPGSSYFSLEFFPPKTTMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELTQRELGLTTCLHLTCTNMSRELVDQALEDAKALGVRNILALRGDPPRSEE
YRDLGEKGTGEGNVDMEEEFEWAIDLVRYIRKQYGDYFCIGVAAYPEGHADESDPAGQSL
EHDLPYLVDKVRAGADFIMTQLFFDVDAYDAFERRLREHESGVFKTIPIIPGMMPIQSYQ
MIKRTTKLSHARMPRVIMERLDRVKGDDEMVKKVGVDIVSEIVTHIQREPAPGPRGFHFY
TLNLEKAVAFILERTNLIPSSPTDSEFAILDVPSSLESLQINGSSHKRPSRRQSSIGSDP
HNRVIISGSKASNPTRETTADEAGIPAEPVNTRANTLAISEGEGSLGREATWDDFPNGRW
GDARSPAYGEIDGYGVSLHMSVNQAIKLWGFPTSAEDITSLFIRHIEGSIPALPWSEEGL
NEETNTIKSQLLKLNQKGWWTVASQPAVNGVKSSDPIFGWGPKNGFVFQKAFVELFIPAA
GWTSLHAKLTSSTVAPTVSWYASNASGSFLSSSPNGPEEGDGNGGGSTNAVTWGAFPGKE
IITPTIIEEVSFRAWAEEAFGIWGEWGRVYGSRSVSKGVVDGCREGYWLVNVIHHGYIER
EGLWELLLS
>A0A0G2GGM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diplodia seriata|TrEMBL
MHISQKLYEGQKNGKPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPTFVDVTWGAGGRNS
TLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALREAYNAGCKNILALRGDPPREKEK
WEATAGGFRYAKDLVKYIRENYGDHFDIGVAGYSEGCEDQDDPNLLLDHLKEKIDAGGTF
IVTQMFYDVDIFLDWAKKVRAKGITVPIVPGIMPINTYAAFMRRANWTKCHVPPDWLEAL
EPVKNDDAEVREIGKHLIANMCRRLMEAGIIHLHFYTMNLAQSTRMVLEELGLTPDMYSP
LEKPLPWRQSLAPGRREENVRPIFWRNRNRSYVVRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNIKLWGMPKTVRDISNLFVKYMEGKLDSLPWSEQPITSEADVLRDNLVS
LNKRGLLTINSQPAVNSAKSTHPVHGWGPNNGYVYQKAYLEVLVSPELIAELITRIERDP
EMTYYAVNKAGDLKTNAPSDGPNAVTWGVFPGKEIIQPTIVETISFLAWKDEFYRLGEDW
AKCYTSVSPSRYIIEDLMDTWYLVNIVHNDFHIDNGIFALFDGLEVKDLDKEPHGTAESE
VNGHSATNGEAHTNGETKIPDTVVNGNSTSAVQNGTAN
>A0A285GTR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. LAMO17WK12:I10|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>Q87V72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>U2QJX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium acidifaciens F0233|TrEMBL
MQHEYRPTAVAPQDRLDSRPDETIAQLLARADRPTISAEFFPPRDDEGAAVLHRSIEQLE
ALHPDFVSVTYGANGSSRERTLDAVRDILASTRLRVMGHLTCTGQSVDELKAVIDGYGEM
GVRHVLAIRGDMPGGPLVPWERHPQGLANATELVELVKSRGEFCVGVGAFPDVHPGSTAE
RDVQVLRDKQTAGAEFAITQLFFRPGAYRRLVDRLRDAGCGLPVIAGMMPVIAIGQIDRF
AELSGAPLPDEMVARLRAVGDDRAAVRGVGTALCAELARELLAGGAPGIQFFTQNRSVAT
LEILGRLAGVSW
>A0A2E2K3F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spongiibacteraceae bacterium|TrEMBL
MSQQRYSFEFFPPKTDLGREKLQTVRAELNKLGPEFFSVTYGAGGSTRDNTVGIVKAMKA
EGLSVAPHLSFGGDDEASMLELINGYKDAGIDRIVALRGDLPSGMGATRLVYAKELVEFI
RKHTGDHFHLEVAAYPEIHPDAKSYQADIDFLKAKLDAGANSAITQYFYSIDAWHYFMDH
CQKAGIDKPIYPGIMPITNFANLARFSRNCGAELPRWMTKKFESYGDDVESSREFGTEVV
TRLSEQLLEAGAPGLHFYTMNTVDPTRQIWQNLKL
>A0A6A8BHT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter haemolyticus|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDADIKRFIEKVQAGANAGITQFFFNPDAYFYFI
ERLGKAGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLSAYGDDSASIKAFGHE
VILKLCERLIAGGAPTLHFYSMNQTEPTRQLVADLGLN
>A0A363S3N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. SPM|TrEMBL
MTAISFEFYPPKTDEQRGQLDRAAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GMDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAPDALTDLKHFKAKVDAGADAAITQYFYNADAYFHFVDE
VQRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMLAYGDDSESVRAFGAEVV
AKLCERLVEGGAPGLHFYTLNLAKPTVSVLKLLNG
>A0A1C6Q0G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. LamerLS-316|TrEMBL
MRELLATGETSFSFEFWAPKTEKGERNLWNALRRVEAVGPSFVSVTYGAGGSTRAGTVRA
TQQIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWIEHP
QGVRYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDSDIGHFVDKCRAGADYAITQMFF
HPESYLQMRDRVVAAGCDTPVIPEVMPLTSVKQLERFAQLSNASLPSSLKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A372NU56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. MYSH2|TrEMBL
MKITEHIQNANGKTLFSFELIPPLKGHSIQGIYDAIDPLMEFKPPFIDVTSLREDFIYKE
QENGLLQKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLHFLGIEN
VLVLRGDARKGDSSFVPTPNGHCYATDLLQQVSNMNNGVYLHEHYDNMLRTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGAKFIVTQMFFDNQKYFDFVNGCRAAGINVPIIPGLK
PITASKQLISLAKTFHIDIPEDLSDAIHEAKSEKDVKDIGIEWMINQCKELVKFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A7C3N6J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MPAERGFELLTRMREVVIIGDGAMGTELWRRGFPHGLPPEQANLTAPDLVKNIHRDYLAV
GAQVLITNTFAANPFRLRDFGLEKRLKELVQASVRLAREAIAESSADAFVAGSVGPIGRL
KEQLELSDEDIESAYRELIVALANEGVDLLIFETFLNLDDLRRAVRVAKQETDLPVIAQL
AAIEDGGRSAEGRAALAVFELEKLGVDAIGTNCGISPIRNLSIVQALARLTELPITAFPN
LGYAQYVDGRFVYLGEPEEFARIGEEIWLAGANLIGGCCGTTPEHIRLLAERLKGKAIRQ
RVTRRIEVKPEEQPKVKSPMPNFLSKLWNEPIIIVELDPPRGLDYEPILEGAKLLARAGV
DAISIGDNSLASVRLSNLVMAFLMQRETGLPTICHFAGRDHNLIGAQSLLMGMAILGIPA
VLAVTGDPARLAPDVGASSVYDLNSFQIIELLSKLNRGVNWVDAPVGKRTDFIIGAGFNP
NVPNLEAEVRRLKRKVERGAQFALTQAVFEPKRIEACGQVMREVGIPIFVGIGILISAKN
AAFWKTVPGVKMPDEILQRMESVPKERQLAEGIAIAQELISVALEHCPGVFLVPPFSRAE
YALPLVEFIRGRKWERFETTASERV
>A0A7K2D9X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
LKSLDAAIEALPAGSRVSVTASPVKGQDATCEITERLMELGHEAIPHVSARMVTDRARVS
ELASWFRSAGVSTMFLVGGDVESPGAYSDAASFLRDLLECDHGLSTIGVTAYPHGHPLIA
EEVLHEALHTKQALLAEAGVEGYCSTQMCFDPALIEGWLRGERAAGMTLPVHLGLSGVLD
RAKLLTMGARLGVGPSLRYLRKNRAAITKLMTSPNYDPDHILMALSPSLDDLGVTGLHVF
TFNQVATTVTWQSSHHG
>A0A839E4R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halosaccharopolyspora lacisalsi|TrEMBL
MSTRTQRLRDYLTHARFEVLPLRGVVEQARYLPASTTVTVTSSPTKGVDATLDTAARLRD
EGFHAVPHLAARMITDRAHLSELVDRCARWGLSEVFVVAGDAQSPAGEFPDSLSLLRAMD
ELGIRPSRVGITGYPETHAFISDAATIQATDEKSRYADYIVSQICYDPDTIASWVKALRA
RGVTLPVHIGAPGAVDPTKLLRISMKIGLGDSMRFLRKQHGVVTKLLSRYTPENLFDELS
PYIVDDAYGIVGWHLFTFNEITKTQQCLQDMAARMQEVPA
>A0A7U9FP09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus capitis C87|TrEMBL
MSQFLNQLQNNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDNVERIHRSYIEAGANVIQT
NTYGANFEKLKTFGLEHRVKEIHKAAVQIAKRTAHHDTFILGTVGGFRGVRQDDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELKSIVVATRRKYEIPIIAQLTASNTNYLVDG
TEINDALKQLVACGANVVGLNCHHGPHHMQRSFSHIELPDNAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIHYIKTAVQGLTPIKDKKVVPITKKS
NHKPTKVVKQNLTSKVKNGPTVIVELDTPKHLDTDTFFENVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQQYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDHSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGSVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A849J0J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTVMDQLNDPRPSFSLELWPPRTPQASARLSEAIPQLAELKPTFVSITYGAGGSTRERTH
ELVVDLAMTPGILPFAHLSCAAHSVAELRDILSRYLNAKVTNIVALRGDPPLASDLPLPD
GELLFASQLVDLIRDCGPFTIAVAAHPEGHPQSKDSSEDLYHFCEKLDKADFAITQFFFR
ADTYFDFIDKVRKERINKPILPGIIAPTSISSLLKMSELSGAEIPQELRDALLGASSDPT
SVRKVGVEAAINLARQLLDEGVPGIHVYSMNSMASTIEIHEGIADLCASDFEYPQ
>A0A373UTR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. AF20-18LB|TrEMBL
MNIKEYIKEQRLITDGAMGTYYEEKYSEDTVIAEKENLKNPEQIKEIHLEYLRAGARLIR
TNTFAANTMFLADMQEVKETVRAGYEIAKEAVTAFQAENGKDIPVFIGADLGPIYDLDHQ
DYDNVLQEYKEICDTFLSCGADCFVFETQSDFTYIEPVTAYIKEKSDAFILVQFAFDKSG
YTRSGLSMQRVAVEASEMENVDAYGFNCELDSTHMYQFMKNLKFSSDKFVSALPNAGYPY
TLRGKTIYSNNASYYAEKMKDIAALGTDILGGCCGTTPEYIALLSGELQDLPKAAKKIEN
VVTQEVTRTPSIFEEKLSRGEKAYIVELDPPFSGDASKVMKGAEDLRKCNVDLITLSDSP
MARARMDAGQLAVKIQQKTGVAVMPHISCRDRNVIALRAGLLGMHMNDVRHFLIVTGDPV
SRADRERVTSVFDFNSIKLMQYVKEMNLEVFAQEPVYYGGALNYHGANPDAIIERMKRKA
EAGCGYFLTQPVYTEEDVERLTYIKEHIDTKIMCGIMPLVSYKNAMFVKNEMPGIHVSDE
IVNRYREDMTREEAEEVAIELSVEIAAKLYDIADGFYFMTPFNRTGLIARIIEAIRQEEE
RR
>A0A3M1U3A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MSWLARAREKVLIADGAIGTRLRQIGWDDRLPPLANLEAPDLVRQVHEEYRNAGCDIIET
NTYGISRYRLPAIVDDRELGALALAGAQLAKAACPDRVVLGAVGPCGKPLVPMGLVEREE
AQREFRVLVESLLEGGVDGFVLESFADLSELEAAVEVVRELCDKPIVASKAFIEDGQTLA
EGYPLEVARKLIALGVDAIGANCVVGPQRMFEIVRWMSQAGETPIFAMPTPGLPQTVGKQ
VVYDTTPEYFGQAAARLVEAGANVVGGCCGIGPEHIRALREAIGERAPKPRTVVSVSERV
EKEALPESEPSELSRKLGQKFVITVELDLPRGLDTSRVLEGARALKAKGADMIDISDGAR
ARLRMAPLAVCYLIQREAGIETMMHVACRDRNLLALQADLLGAHALGIRNVLPITGDPAS
IGDFPAATSVFDIDSVGLVRVLHRFNQGFDLAGNTVRRKCAFTIAVAFNPAAQAFEREVD
RLKAKIDAGAHLIYTQPLFEDKHVERAVAVAREVQRPILIGCLPLRNARHAEFMHNEVPG
IEIPEWVRKRMHEVGEEEGPEVGIEIAQEFCRKLPGVADGVYLMPPFGRHEVAERVMEAV
L
>A0A7Y1Z8D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
PGLKPIATKKHLNLIPHRFNVDLPQDLIMEIVKCKDNKQVRDLGIEWCVAQSKELKAAGI
PVLHYYSMGKSDNIKAIASQVF
>A0A1G1GE63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium GWD2_57_9|TrEMBL
MKSGSTLEKVLASGQPAVTAELGPPMSADGHEVVKKAQLLKGFCDAANITDCQTAVVRIS
SIAAAAIAYQNGLEPVMQMTCRDRNRIAIQADLLGAAALGLKNCLCLAGDHQKFSAAGKL
KGHPGAKNVYDVDTCQLVGILKKMRDEGKQEGGDPLEVAPQFFVGASWTPMGDPIDFRPI
NLLKKVNAGADFIQTQGIYDMELFRKQMEKIRNMGLHERTAILAGIIVPKSAMMLKYMDS
SVAGVSVPKEMIDRMNKAKAAAGEDKKKMKELQEQEGIKIAIELIQQALETPGVKGVHIQ
AIEWESAIEGIVKAAGLYPRPQV
>A0A7C7L2S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MSHIKDKFERGEFVISAEVGPPKGTNVEGVLEEAEKLRDRVDAFNVTDQQSSVMRLGSLV
TCYLLKQRGLEPIYQVTCRDRNRIALQSDLLSAGVLGIENVLCLTGDHVSLGDHPQAKPV
FDLDSVQLLKVAKALTEGHDMVGNELDGKPDFFLGAVVSPGYEPLELQIIKMEKKIEAGA
QFFQTQAVYDPKVFERFVQQVEKFNIPIMLGIVLLKSAGMARFMNE
>A0A090APG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioploca ingrica|TrEMBL
MSCEFFPPRTEKGVEKLREIRQQLQVLQPAFFSVTFGAGGSTQEQTFETVIDIQQYSGCE
AAPHLSCIGSTQEQVRQLLQDYQAHHIRRIVALRGDRPSGWAGPLGEFGYANELVAFIRA
ETGSHFHIEVAAYPEFHPQARSARADLNYFNQKVQAGADSAITQYFYNAEAYFRFIESCH
AIGIDIPIVPGIMPISNYEQLARFSETCGAEIPKWLRWRLQELIDDKASLQALGLDVVTR
LCERLIAGGAPGLHFYTLNQAELTLTIAKRLNLFTSAT
>A0A3D5GG68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTYELIPLKNLTDQSEHLPSGATVSVTCSPAKTIDDTLDLCAEYADKGFAVIPHIAARMV
EGEDHVDRIARRVRDAGIRKVFCIGGDADPRGPFADSAAFLRSFLDRRPEIDAVGIGSYP
DGHTAITEQVLDDAQVEKQEIIRQAGLQGYMTTQMCFDAQTIVSWLERRRAAGVSLPCHL
GVPGAVDRTRLLAISIRLGIGHSARYLKKNKASVIRLMSPGGYNPNKIVAPLSSRANELG
IEGIHCFTFNAVDTTEVWRRKSLKKLGA
>A0A022XSN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton soudanense CBS 452.61|TrEMBL
MSQALRPLFVTVTWGAGGSTAARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEET
KALGIRNILALRGDPPRSEEYNIDGEDDSNKDFNYAVDLVRYIRKKYGDYFCIGVAGYPE
GHADESHPEVQDLLKDLPYLIEKTQAGADFIMTQLTYDIEAYKKYEALLRNHESGTFKTI
PIIPGLMPIQNYHTLTRVTKLSHAKIPPQILAKVEACKADDEAVKRVGVDVVSDLVENIK
KVATPGHRGFHFYTLNLEKSVSFILERCNLIPPSSEAPSDSELDFESAVYAASGASNGVA
TPDGRSTNVNRLRASSMNSQPHNRVIVDRLTRASDRSERSSTVHETSAQTAGYPALNPPN
RNTALQISEGLGSLGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTAQVARKLWGTP
TSRDDISNIFKRLLSGELHVVPWSEGGAGEEGGLNPETATIKAELLKLVEGRGWWTLASQ
PAVNGVRNDHPVFGWGPRGEGFVFQKAFVEFFCSGDDFHSKLKPLLQSYGHDEFAWFATN
AKGDFQSSTSPETSTQPPTDPSEVPFDADPLTEMDNGSVNAVTWGVFRGKEIVTPTIIEA
VSFRAWGEEAFGIWEEWRRVFPRGSPSEKLIREIKDDAWLVCVVGQRFGAGGDVGKESNE
EDGKLLWKVLAGE
>A0A1G1G0A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium GWD2_57_9|TrEMBL
MKLSDILKTRSQGISFEVFPPKSEDGKDALLNTVKDLSGFDPLYVSVSYGAGGTTQERTL
MTLRWLRQETSLSLMSHLTCVGSSRASMDSLLREFQSLGVENILALRGDPPKSIPDFDPL
KGEFKYARDLVEFVRDYKAFSIAVAAYPEGHRESPSIEKDLEYTKQKIDAGADIAITQMF
FDNRYYYEFRERASRAGISVPILPGIMPIVDCRKMVTFAEACSTTIPQEILDRMEPVLDL
PEEMRKLGVEFAIRQCQDLIRNGVRYIHFYSMNRAETMRDILSVVRYN
>A0A2E8LJK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MMSDADASAPGRPGRRGSGRTKAERATHRRLLEGMTYELIPLKNVHEQAAFLPAGSTVSV
TCSPAKTVDDTLDLCATFAGQGHTTIPHIAARMVEGEEHVDTIVRRVNEQGIRKVFVIGG
DAEPRGPFTDAAGFLRSFLDRRPDIDVVGVGSYPDGHSTIPEQALVDAQLEKQELIREAG
LEGYMATQMCFDADTIREWLVRRREAGFTLPCHLGVPGAVDRTKLLTISIRLGIGHSARY
LKKNRTSVIRLLSPGGYNPNKLVAPLASVADELDIAGIHCFTFNAVDTTEDWRRKSLKKL
A
>A0A3C1CJP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MARISDLLAGGRTYSFEFFPPKDEAERATLVRTLRDLEPLAPSFVSVTYRGGRESRQRTY
DLVTGILRTTTITPMAHLVCVAHTRLELAEILLSLRQGGIENLMALGGDPPTDPAAGPGE
LLHAMELVELARAIGGFSIGVAAHPAGHPLSPDMASDRRWLAAKMALADFAVTQFFFEPG
EYSGLVEDLAALDEHKPVLPGIMPVTSLRSVPRMAQMGAAVPAWMVERLEAADAAGGDEA
VRKEGIELACELCRAVLDTGAPGLHFYTLNRSTATREIYSSLGLGPAPAPSAAAPGGAIG
AAQ
>A0A2E2ERA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIKNANGKTLFSFEIIPPKKGNSIQQLYNNIDPLMEFKPPFIDVTTSREEYVYIE
KEGLLDRKITRMRPGTVGICAALKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGINNV
MALRGDAMKHQQYFEACKGGHQFAKNLVGQIQNLNRGKYLHDVIEVDDKADFCIGVAGYP
EKHIEAPSLKTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEAAKQEGINVPIIPGIKP
IAVKRHLQLLPQVFKIDLPEDLIDAVDNCSTNEQVRQVGIEWAINQSKELQKAGVPVLHY
YSMGKSDNIKAIAEAIF
>A0A2D8GHK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MALFKKNEVPEIVESDEARAHREHLTRSFTIEVIPMKSLANARKHLPAGAPLSVTASPVK
GLEETQRLTEEFQAAGFEPVPHISARMVRDRAHCAELAHWLRDNGLKKMFLVGGDQDPPG
EYFDAVLFLKDFLEQDHGLEGLGVTSYPDHHAFISDEKLHEALHAKQTLLAEAGLPGWCS
TQMCFDAEVIEAWLRKERAEGLTLPVHLGVSGVVDKAKLMTMGVRIGLGASLGYLKKNRA
AITKMLTSTSYDPNDLMMPLSNAALELGIEGVHMYTFNQIEATEQWRAEALAELAG
>A0A349BTN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKITEHIAQSSGATQFTFEILPPLKGQSIHALFGALDELMEFKPPFIDVTYHREEHVYKE
VGNGLLQKKVIRKRPGTVGICAAIQSKYKVDAIPHILCGGFSKEDTENFLIDLDFLEIDN
VVALRGDALSNETYFNPDPEGHSYANELVEQIAALNQGKYLDESLLNSHATNFCIGVSGY
PEKHMEAPSLESDIHFLKKKIKAGAEYIVTQMFFDNQKFFDFVAKVRAEGIDVPIIPGLK
PLSTLKQLNMIPHRFHVDLPEALIKEIIKCKDNTEVKQVGIDWCIQQSKELKSAGLPFLH
YYSMSKSDNIKAIAKSVF
>A0A2E7A4A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTFFRKRSANPVHQATRANLLRSARFEVIPLKNLEAQLEYLPEGASVSVTASPAKTLEDT
WTLSQTLADQGFTPVPHLAARMVTSEKQLRQLVSQLADIGVSEVFIVGGDAPDPFGPFLD
SIQVLDSILELDHGLSHIGVTAYPDGHSFISEGALSAALHAKQEMLASAGVSSHASTQMC
FDPGAISAWLQREREMGLTIPIHLGIPGAVDRAKLLSIGARLGVGASLRFLRKNRSTVTR
LFSPGGYDPNKLLAPLSSVLEPLGISGLHIFTFNQIEKTEAWRRSTLDIGNK
>Q39YC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter metallireducens (strain ATCC 53774 / DSM 7210 / GS-15)|TrEMBL
MNFLERLNSEVLVGDGAIGTMLYAKGVSLDANVEHLNLVRPELVLELHREYLGAGAKVIE
TNTFGANWTKLSAIGLDKREREIILRGARLAREAAEGTDAFVAGSMGPLARVKGDERELS
PAETTEIFRRQALALAEGGVDLLILETFTDLAQILCALSAARETGLPVVANMAFLENGRL
AGGADVERAARELTAAGASVVGANCGAGPLEVLGTIRRMAGATALPIAAYPNSGFPEYVN
GRHVYRTTPDYFAERAAEMVAAGAALVGGCCGTTPEHILRLAERLAGLRPAVRNVAVPAV
SVEERRGESTEAEGFLARWGEEPVVTVELDPPKGFDCGKVIEGSRVLKGAGADAINIAEN
PLARIRMGNIALGHLIQQEVGIEVIVHVTCRDRNLLGLQSDLMGASLLGIRSILAVTGDP
ARIGEQAGASSVYDLNSFTLIKLLADLNAGVNALGNPLGRGAGFAIGCVFNPNSQRMEVQ
AERLAKKVANGARFVQTQPLYDLARLDEMLERTSPLGIPVLPGILPLVSERNCEFLHNEV
PGIVIPEDIRARMRGKEKDEGVREGLAIAREFIDAVRGRVGGFYLMPPFGRYEIAVELVR
HIKGK
>A0A848B003|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Victivallis vadensis|TrEMBL
MNLLQQKLAESLTIFDGAIGTEIYRRNFFVNASFEQLNLTAPDVILDIHHQYLKAGAEVL
TTNTYNANSRRLAKFGLSEQTEAINRAGVKLAREAAAGKALVAASVGPVGEPDSDQDRRT
RAELLAEQIRALSDADFIIFESLRRAADLKAVLEAVAEFPELVYVPSFAIEPHPHINDSA
TIAEFMEQLNASRPCPAPTAIGLNCGGGPESTLGVLEELTALTQLPVIVQPNAGQPKGVD
GRMIYMTSAEYFSTYAKRYAMLGAAAIGGCCGITPDHIEELARTIKPLMQAEKRALPALE
VKECDLKPEVPLAERSRIGCKLADGAFIKLVEITPPRGFDLTGTIAGAAKCKAAGIDAVN
LPDGPRASARISPLVTALEIQRNAGIETILHCCCRDKSLIGLQADLLGCAGVGINNILFI
TGDPPKLGDYPFSSGVFDVDSVGLVKIQKRMNQGVDLGGKPLNAVTKMVIGVGADPNAID
LEREYRRTCEKVEAGAEFIITQPVFAPEALFVFLDRIAHLNVPVIAGIWPLTSLRNAEFM
RTEVPGVVVPDAVMERMAADESKEAQREAGIAIARESVAAIRSRVRGIQVSAPFGNVDTA
LRVLA
>A0A7K2S8B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8364|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A8J4ZY93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nymphon striatum|TrEMBL
MAQLQIVYWRDIPAQVIVKAGRRNVAKRELSLRFTEAIDMCAMRTGAAETDDYLEEWRRA
DPVEVSDDLEAEAQKAADALETEYDKQRLVALVKSGDLEGLFPSGTRVYITDVGTDTAET
LSAGAKRVTDMGYTAVPHFASRRLTTKEALETRIKMMTQEAGVTDVLVIGGGLEKEAGEF
DASMKVLETGFFDKYGIKHMGVAGHPEGSPDFSDEVAIEALKLKQEFHNRSDIELRIVTQ
FGFDAEKFTNWANGLSAHGIDLPVHLGVAGPAKITTLIKFAAMCGVGNSLSFLKKRGGAI
MTMAAGFDPDEIVNPIEENALSGNSAIKQIHVFPFGGMKKSAEWLKDRGSWNA
>A0A3B0UCM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKVTEHIKQANGKTLFSFEIVPPQKGQNIQDLYDNIDPLMEFKPPFIDVTTSREEHIYIQ
KGALLDRKITRMRPGTVGICASLKYKYNVDAIPHVLCGGFTKEETEYVLVDCHYLGLDNV
MALRGDAMKHEKYFKPTTGGHQYASELVVQINNLNKGKYLHEIIETPYNSNFCIGVAGYP
EKHLESPSLETDLRRLKEKVDAGADYVVTQMFFDNKKYFDFVEKARNIGITVPIIPGIKP
VAIKRHLQILPQVFKLDLPETLIHEVEKCKNNKEVRQ
>A0A3B0T5A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
CPMNCPKRIRNGPCGGVRADGTCEIEPEIPCVWVDGWQGIAGTGRFSRYMMPRRAAESLR
QGRSSWMQIIEHQTVTQPEEDRIPGSDDKNSERSSPYPPNSFEALLASGTFAVTAELSPP
DSANPEDIAVCARHFEGLVDAVNVPDGSGANCHMSSLASSLILRELGFTPIMQFACRDRN
RIALQGDILGAAALGIKNLLCLTGDGIGTGDQPGAMPVFDLDAVSLLRTARTMRDKSRFM
SGRPIMTQPDLFLGAALNPFCPPFDARPYRLAKKIAAGARFFQTQYCYDIDLLEAFMKET
KRLGLHKRCHILVGVGPLISARSANWIVNNIPGIHIPDALIMRMQDAKDERKEGKRICIE
LIEKIREIDGIAGVHVMVHKHERLLAEIIHDSNIRQNR
>A0A1V4R998|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacteraceae bacterium 4484_166|TrEMBL
MYKNFIEKLQNSSFTTLETTPLHEPTLDSIISDLKSKDFLDKIDAFTVTDNPLARLKYSS
LLASIKLFDRFKKPVIWTSTMRDRNKIALQSDLLGANDFDLRAVLCLTGDPANMSDQPKS
KGVFENNSNLLLQMIYSFNNGMDYSGKMFKTKPKQIYPFAVINSYSKSYKTLEKKILNKI
KYGAVGIITQPVFDKQNAIKLLESFNNCSSMFDDDRAKSQIIFGIFAITKLRTAQFLASH
VPGINVPQLWIDKLSIASKIGEKEEYKVGMELSLNLYKDIKKIHNKTHIMTADKFDIAKI
LLEG
>A0A4R7K1M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halospina denitrificans|TrEMBL
MQSQKQFQRRFSFEFFPPKTDKGVTQLQTTRDRLAELNPDFFSVTFGAGGSTREGTKNTV
IDLNSQGISTAPHLSCVGSNKEIISELLDTYKDNGVDRIVALRGDIPSGMGNTGYGEMRY
ANELVEFIREHSGDHFSLEVGAYPEFHPQAPNAEADLLNFKRKIDAGANSAITQYFFNAE
AYFHFMDRLEKMGVNIPVVPGIMPIINFQKISQFSEMCGADIPRWIRKQMEAYGDDSESI
KKFGEEVVTRMCEELLDAGAPGLHFYTLNQADASLNIWHNLGLDKERAEKIAF
>A0A225NCH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinibacterium profundimaris|TrEMBL
MTVPEISFEFFPPRDLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRDLTRDAVATLHK
HSGLKVAAHLTCVDATREDTMAIVDGFAQAGVRDIVALRGDPPKGTDKFVAHPDGFANSC
ELISALAKAGDFNIRVGAYPEAHPEAANAQADIDWLKAKLDAGATEALTQFFFEADTFFR
FRDACVKAGIDAPIVPGILPIENWKGARRFAMSCGTHVPQWLDDAFAAAERDGDGRTDLL
ATSLCTELCSDLIEGGVDKMHFYTLNRPELTRDVCHALGVTPKVALENVA
>A0A3B1AYC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MESQKKYKPAFSIEFFPPKTEEGKIKLRKTREELARLNPAYISVTYGAGGSTQQGTLDTI
LEIKNAGIDAAPHLTCVGSTKENIRELLQTYIDNGVSRIVALRGDMPSGMHEMGELRYAS
ELVEFIRAETGDHFHIEVAAYPEVHPQAKSATADLEHFKRKVDAGASSAITQYFYNADAY
FCFVDDCEKMGLNIPIVPGIMPITNYKNLARFSDMCGAEIPRWLRKHLEDFGDDVASLRA
FGQQVSTQLAKTLLDQGAPGLHFYSMNQADSTQAIWHELQLSN
>A0A1Y2P3B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces fradiae ATCC 10745 = DSM 40063|TrEMBL
MALGTPSTRTDRARTVRDLLANGTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVT
YGAGGSTRTGTVRATEQIAADTTLTPVAHLTAVGHSVAELRNMVGQFADVGIRNILALRG
DPPGDPMAEWVAHPQGLDYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDTDVRHFVDK
CRAGADYAITQMFFEPESYLRLRDRVAAAGCDTPIIPEVMPVTAVRQLDRLPQLSNAHFP
AAVRDRILAVKDDATAVRSLGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQQS
>A0A4R2J143|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2541|TrEMBL
MAHGLPSTLSGGTPTIRDLLATGGRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGAGVRNMLALR
GDPPGGPNQPWVAHPDGLNHAVELVELIRSLGDFCVGVAAFPDKHPEAASLEADAQVLAA
KAAAGADYAITQMFFGADDYFRLVERAGQLGCDIPVLPGIMPVTNIKQIQRMAELTGMAL
PAAVTDRLLAVEDDPGAVRAVGIEIATELCERLLAGGAPGIHFITLNRSTATRQVYLNLQ
SAVVS
>Q74EU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)|TrEMBL
MTGTPSSLSAALAAGHFVVTTEICPPKGSNCTEFLRKARALRQAVDAVNVTDNQGANMRI
SPLAPAALLVREGIEPILQLTCRDRNRMALQSELLAASALGITNVLALTGDFITFGDHRE
AKPVFDLDSVQLLRIITGLNEGRDLSRTALTGATSFFAGAAAAPEAEPFALTLSKLAKKA
AAGARFLQTQAVFSPERFARFADATRPLGMKIIAGILLLKSPGMARYVTERVPGLKVPPE
LVAELESASDPLAAGVEIARRTVAAVRPFCDGVHIMAMGREDLVPAIVAGVERDSQEHTT
I
>A0A5Q4YUM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia dioscoreae|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLATLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRQDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCGRLIDAKVPGLHFYTLNGAAATKAICERLNT
>B8I637|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminiclostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10)|TrEMBL
MTALSTKSIIIAMKGGLSTRLIKRKRKGKEDMNIFSNRDYFLFDGAIGTYYSLKYRSNTP
CELANINERENIFNIHSEYIQAGVNAIKTNTFSANRFSLGCNQSEVEKIIKSGYDIAVQA
CSGQEVVVFADIGPIPDEKGINPKEEYIKIVDIFLECGAKNFLFETFANTDILIGVAAYI
RLRLPEAVVVTSFAVYPDGYSKEGLFYVDLMDKMYASGLVDAVGLNCISGPAHMYRLIKK
ADIRGKSIIIMPNSGYPGSERGRTVYSDNSEYYAEKLLDLKNLGVKIFGGCCGTTPKHIA
AAAQLLSRNPTKTDAQSKTHIETCNLANENILDKLVKTKKPILVEVDPPFDTNWEYMLRD
TLLLKQAGADIITIADSPLAKARAESTIMAAKIQREAVIPVMPHITCRDKNLLGIKASLL
GVHIEGIRNVLVITGDPIANIERSRIKGVFSFNSSNLANYIKSLNSNVFCGQEIKIAGAL
NVNAVNFSAELKKAFTKIENGISCLLTQAIYTKSAVDNLLKAVETLKVPIFAGFMPIVGY
KNALFIDNEVPGIDIDNETIEKFRDKSREESEKLGMEITMDILKEIYPHVSGIYLMTPLK
RTNVICELIKKIKEI
>A0A7S0TX67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hemiselmis andersenii|TrEMBL
IRGDPPPGSDQWVQTDGGFATARDLVAYIRRKHANAFSIAVACHPGGLPGGGDSVQNFKS
KIDAGADYGVCQLGFDTSAYSDFVKGCKGAGITAPIIPGVLVPPPSPAQVSSVCKHCGVP
PPPPPPR
>M7N3R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomarina gelatinilytica|TrEMBL
MKVTEHIKNANGNTLFSFEILPPLKGQNVQSIFDNIDPLMEFKPPFIDVTYHREEYVYKE
LENGLLQKKVVKKRPGTVGICAAIQNKYRVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKTETYFKAEKEGHHYASELVTQISDLNKGTYLDEDLLNSSCTNFCVGVAAY
PEKHMEAPSLDSDIHFLKKKIKNGAQYIVTQMFFDNNRYFEFVEKCRRESITVPIVPGLK
PIATKKQLNLIPHRFHVDLPEDLILEVVKCQNNEQVRQLGIEWCVQQSKELQKAGIPVLH
YYSMGKSDNIKAIASQVF
>A0A1G1P1L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium RIFCSPLOWO2_02_FULL_50_19|TrEMBL
MTLKEKIKNKKFIITSEIGPPKGIDAKVILEEGLLLKDRVDAINVTDSQSAVMRLGSLAV
SRLLKEEGIEPIYQLTCRDRNRIALQSDALSAAALGIENILVLTGDHPSRGDHPEAKPVF
DLDSVQLIEALRRLEGGKDMAGKELKGAPKFCVGAVVNPGADPLEPELIKFEKKLKAGAE
FFQTQGVYDVNGFAKFIDRVKGYNTCVIAGIILIKSADMARFMNKNVAGIFIPDDIIKEV
DGATDKQEKAVEIAARTIKELKGLAQGVHIMSLGWNRLVPRILDKAGL
>A0A1S1Y065|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas sp. LWB|TrEMBL
MNISFEIVPRSLAAFDEQYAFVQGLGNGINIINIPDIQRFDTRSWELATRIDRGKYRFVP
HFRAIDFKIESGELYRIIEQYQLDSVLLVTGDPPEGLKRAFYNTDVVDLIRATHQRFPEL
NIYAGFDPHRHGLRDECDYIQRKADAGATGLFSQPFYDSRMVEIYAEQVRGLETYIGISP
IITKASMNYWEVKNQVKFPADFRPDYDWNVAFANQLIASATIADLHVYFMPIRIDLQKYF
ERIDLPR
>F0C4K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas gardneri ATCC 19865|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDT
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLIGR
>A0A1F9KMA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFCSPLOWO2_12_FULL_60_19|TrEMBL
MKLRDLYARSGPTFSIEFFPPKTEKGEEALFNEIAALKSLHPAFCSVTYGAGGSTRDKTV
DLVERIHRECALEVMCHLTVVGQSKEEVRSVLGRLQQMGIENMIALGGDPPQGVEDWTPH
PGGFHHSIELVKEAAARRWFSIAVAGFPEVHPRAESRESDLRYLKEKVEAGADVVITQLF
FDNEDYYRYVEDVRKLGVSVPVVPGVLPVLSVPQVRRFTALCAAKIPLKLERLLAKVEND
EEGAVALGIDYATEQCAGLLKFGAPGIHFYSLNKSRSVKAIFANLNL
>A0A4Q7BM51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WCHAc060033|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLDDFN
GKGTPVAPHLSCIGDSKQRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQRFCDKARAGANAALTQFFFNPDAYFYFV
DRIQKEGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A414JF34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM28-11LB|TrEMBL
MRVDEVFKQAASLGTVPVSFEMFPPKGELTLDTARKVAGSLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVNNILALRGDLPAGAT
EDDKPASEYAHARDLIPELVDAGFCVGAAAYPEGHIACKDLSLSVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMSKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVEYATRQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A1I4MQR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces pini|TrEMBL
MRTTRTLREVLAAGERSYSFEFFPPRTEAGERTLWDAIRRIEALRPTFVSVTYGAGGSSR
DRTVAVTERIAAETTLRPVAHLTAVGHSVAELRNIIGRYADAGVRDVLALRGDPPGDPGA
PWTPHPQGFTHAHQLVSLVKEMGDFSVGVAAFPERHPRSPDWASDIRHFVAKCRAGADYA
ITQMFFHVEDYLRLRDRVVAAGCETPIIPEIMPATDARQIARFAELSGAAFPEDLARRLE
AARGNPAAGHRIGVDHATAMAERLLAEGAPGLHYITLNRSTATLDIHHNIHGSIQSSIQS
TQTPRSTRHALAAHR
>E3H3W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia dentocariosa (strain ATCC 17931 / CDC X599 / XDIA)|TrEMBL
MGWTDKVLPPEPIEVNSLRVLLRFGVPSGTLLSGEHGGMKMTTVHPALSYELYPPRSHAS
CDSLLKTIAELEQTNPDYVSVTYSGDAQRRQKTLALLDHLVHETSLNPLAHLICVGHSVA
DLERSVRLILGLGVRGFLALRGDIPPENTRPLELPFARYLVELIRRVEREDFAHLAAGKV
SIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVFFETERYSGLVDAARLAGVEM
PIIPGIMPVTSLTRLTKLCELAGLEVPRELAHRLETASNPRELHRIGVEHALNQCRKVLD
AGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDLQYL
>A0A2Z4APP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Moanabacter tarae|TrEMBL
MAKIPNQTTGAGWHKASLRHLLSKSDEFVNIVELVTSRGILTEENSRKVLTLARRLVEHP
KIHGASITDNPGGNPMICADTLGRDLISRGQEVIIHLSCKDWNRNGLEGRAWQLASEGFD
NVLTLSGDYPISGYEGQAEGVFDIDSVGLLKMLKDMNRGLEEKKRNRKKTMMPTDFFLGA
VVNNHKRLESEVMPQYFKLIKKIKTGAAFIINQVGYDSRKQDELIKYMQKKGLNVPVIAN
VYVLKASTARFFHGGTIPGIEVTDELLELCQAEAASKDKGKSFFTEFAAKQCAIAKGLGY
RGVYLGGHLEYEDYEQIIEKTNNYGKDDWREFAKEIRFSQPGEFFYFQKDPESGLSSTKV
NQEYLKSKNLSQLKKTRRQISPAYRLNRRVHNFVFEKGSPCFGIGKKFYKMVDDSRNGIR
KFLHGLEQAIKMPAFDCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTRKGKCEIGEKE
CIWSRAYNRLKAYGHEEELLTREVIIKDNSLSGTSAWMNTFLERDHLSKTHHPKKGSL
>A0A1S6HRH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella psychrophila|TrEMBL
MFIILVTLNQLKQLSRAVEGIGMGFHHAQHSTSLNQSLAELNGDINVSFEFFPPASPEME
KILWNSIRRLEPLKPKFVSVTYGANSGVRDRTHGVIERIQRETDLVAAPHLTLVDASDEE
LKELAKHYWNSGIRDIVALRGDLPDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPD
AKNAQADLINLKKKIDAGANRAITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFK
QLKRFAGMTNVSIPGWLHKQFEGLDDDPATRQMVGANVAIDMVKVLSREGVKDFHFYTLN
RAELTYAICHTLGVRPGQ
>G1SSR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryctolagus cuniculus|TrEMBL
MDLPAGHRCPSPGLWAPQARGRLSVPPSISRNPAMVNEARGNGGLHPRSEGSSSGSESSK
NSSRCSTPGLDPERHEKLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRFDRMAAGG
PLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETMLHMTCCRQRREDLTAHLHKAKQ
LGLKNILALRGDPVGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDICVAGYPKGHPDAESL
EADLKHLKEKVSAGADFIITQLFFAADTFFSFVNACTEMGITCPILPGIFPIQGYHSLRQ
LVKLSRLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREV
ATTEVLKRLGLWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNG
RWGNSSSPAFGELKDYYLFYLKSKCPREELLQMWGEELTSEESVFEVFVRYLSGEANQQG
YKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPGGGYV
FQKAYLEFFTSRETVEALLQVLKNYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGR
EIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFP
LDNCLWQTQLAVAETAREAVRTWGLLFSFRAPGAVSCVTPAP
>A0A1F6TK52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Muproteobacteria bacterium RIFCSPHIGHO2_01_FULL_65_16|TrEMBL
MNSQKKFPRAFSFEFFPPKDDDGRAGLRDAINQLAPLKPKFFSVTFGAGGGIRAGTYETV
KEIQARGLTAAPHITCTGTTRADVKQLLRSYRELGIGRIVALRGDRPKDAPAAGDFSHAN
ELVAFIRAETGRHFHIEVAAYPEIHPEAPSAATDLENFARKVRAGADSAITQYFYNPDAY
RRFVDDCEALGLDIPIVPGIMPITNYKQLARFSDGCGAEIPRWVRKRLEGYGDDLDALRA
FGLDVTTALCEKLLAAGAPGLHFYTLNRAGAARALWERLGL
>A0A1F1GIW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC068F09|TrEMBL
MTTVHPALSFELFPPRSHASCESLIRTIAELEGTNPDYVSVTYSGDAKRRQKTLALLDYL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDVQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSARLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMSVPADLAYALETATSSAE
LHRIGVDYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEF
A
>E6X5S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulophaga algicola (strain DSM 14237 / IC166 / ACAM 630)|TrEMBL
MKVTDHIKNANGNTLFSFEIVPPVKGNSIQELYANIEPLMEFNPPFIDVTTSREEYIYVD
KAGLYDKKITRMRPGTVGICASIKHKFDVDTIPHVICGGFTKAETEYMLIDCHYLGIDNV
MALRGDAMKEEKYFKPTEDGNCFASELVSQIQNLNQGRYLHDDVQGEDRSNFCIGVAGYP
EKHLEAPSFKSDLIRLKQKVDAGADYVVTQMFFDNQKYFQFVEAAKEIGINVPIIPGIKP
IAVKRHLQLLPQIFSLDLPHDLVEAVEACKNNAEVRQVGVEWAIQQSKELKAAGIPVLHY
YSMGKSNNIKAIAKEIF
>A0A1W2CT64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocicer vacuolatum DSM 3385|TrEMBL
MQFRRRFEAGEFTCLVQIDPPKGTDVSTMVDGAMGVKGIADAFIVPEMANAVMRMSSLGA
SVVLRNNGVDAVMQVSCRDRNRLALQGDLLAAAACGINAMMVVTGEDPSFGDHHTAKAVY
DVDLGTLLKGISSMEKGRDMAGVELSGAPDFLKGATLNTCLRGADREVELDRMKEMVDAG
VKFFITQPLFEFSMTQPFFKTADNYGAKIIPTVLLLKSLGMARYMARNVNYVNMPDAIVH
RVLKASDKVRECTRMARETIEAVKKEGFAGVNVSTLGWEHKLPEVLGVMDGLKG
>A0A3C0XT89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriia bacterium|TrEMBL
MFDLDSTQLASIALGMNEGRDMMGRDLKGGTDFYIGAAMFPEAEPWDVQLARIEQKVAAG
VRFFQTQAIFDMEKLQRAVDAVRPLGVKVIAGVLVIRSPRVVDFVNRNLAGLMVPDHVAD
RIRSAPDPAEEAVRLAAEQVRDIREIADGVHVMPLGLDTEVGRILDGSG
>A0A1W1YPN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocicer vacuolatum DSM 3385|TrEMBL
MKNRTFDDAEKVIVNDLDFEKFILTIEVVPPGGDDPEALLTSLEALGDLPVDGFSVATNP
VAKPRMCAMALCALIQQRTGRPAVFHCTTRDHNRISLQSLMWGAKALGVSSVLVATGDFV
AMADRKIVSDVKDVNVFELVTMARESGLHTGAVLDFRPEVNGLEREVKRLEKKVAAGAQY
AVTQPIYDRDTAKEISQAVAHLNIPVIMGILPLRTPRHADFLHERVAGIAVPEALRKKMH
SASDSVAQGVSNARDMVAVAREFFQGACVMPPFDHYEILPDVLGRDL
>A0A3N8C7I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Bp9126|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDREAIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATRTICERLGA
>A0A143XF11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacteriaceae bacterium CHKCI004|TrEMBL
MKLSSIFKSDSRISFEVFPPKKWEGFPNLYETLNALKELNPSFISCTYGAGGSNSKKTAE
IVSYIQNKLGIEGIAHLTCAALTEDSFLSTIRTFQQMGIHNVLALRGDKPADMTEDSFRS
RTYKHPSDLIPALKDAGFTVAAACYPEKHFEAATMEEDLHYLKYKVEQGADFLISQLFFD
NDIFYRFLDMCRKMEIYVPVEAGIMPITSAKMIGTTINLSGASIPKAMADLLARFQDSPE
DMRKAGIDYAARQIQDLQAHGVDSVHIYTMNHADTARDICRIL
>A0A7J5KZS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides stercoris|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLWEFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEKNGYHHAVELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTNEILKCKNDAEAQQVGIEWCVQQCKELMKHHIPSIHF
YSIGAVDSIKEVAKQIY
>A0A8J8FPY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomarinum sp|TrEMBL
MKFSFEIVPRTEQAFDQQYDFVSTLGDSISMINIPDIQRLSIRSWETGGKIDRAKYNFVP
HFRATDFSLRSGDIFRIIEENQLDHVLLVSGDPPEGIKREFHNTNVLDLIRVVKQKYPDI
TIHAGFDPHRSGIQEECNYVQRKVDAGASSFFSQPFYDIRMVEIYAEHMQGIETYIGLSP
ITTAASKNYWEIKNKVKFPTNFKAEIDWNIDFSNKVIAMAKEVGFNIYFMPIKIDLDEYF
GRLDLGA
>A0A6J4IRV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Chloroflexia bacterium|TrEMBL
MAHPFLDRIARGPILGDGAMGTQLYAHGIDLEGCFDAVNLDNLDLVRTIHRDYINAGSEL
IETNTYGANRLKLERFGLGDRVADINKRALRAARDAREIGGQTVLIAGAVGPLGAVLEPY
GNLKPAKAREVFAEQIAVLLEQGADLLMFETFGDLQELLLAIDAARSVGDLPIVAQMSFD
SDGRTAVGNTPEEVVRALVARDVAMIGVNCSVGPQRLFKVVEAMHIAEPNARLAAQPNAG
WPTELNNRILYPSTPEYVARYARRMIEELGVSLVGGCCGTTPDHIAAIRGQLTSLQADAV
ASHVHVVTSPEPARRAATAVPQTLLAQKIEAGEFIVSVEIDPPKGHNPRKCIDGALMLKE
VGVNFINVADSPMSRVRMGPLAMCSLIQRETGLETIIHFTTRDRSLMGLQSDLLGAHALN
IRNVLTLKGDPPTLGNYPGTSGVFDVDTLGLVRI
>A0A4Q2JB90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenobacter cavernae|TrEMBL
MSQNRTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPEFFSVTFGAGGTTRDGTLAAVLEIQ
GEGHAAAPHLSCIGSTRESIAAILQEYRNHGIRHIVALRGDIPSGMVGIGEFRYANELVA
FIREAHGDWFHIEVAAYPEYHPQAVSAAADIDNFVRKVEAGADAAITQYFYNADAYFHFV
DTVRAKGVEIPIVPGLMPIANFSQLARFSDACGAEIPRWLRLKLQAYGDDIASIRALGLD
VVTELGDKLLTGGAPGLHFYTLNQAGLVSTVWQRLGL
>A0A4V2JC76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus subflavus|TrEMBL
MSRPTVSFEFFPPKTLDASFRLWETARALAPLDPDFVSVTYGAGGTTRKLTHEAVTTINR
HYGVPVAAHLTCVEATRAETMEIVQAYADAGIRQIVALRGDAPKGQDRFAPHPEGFANTV
ELIQAIAARGDMTIRAGAYPEPHPDSPGTDADVAWLKRKIDAGATSAITQFFFDADTFFR
FRDKCAAAGIRAPIIPGILPIQGWAGARRFAATCGTSVPAWADEAFSKAAAEGPEAERAL
SLRVCIDLCHRLMDGGVDRLHFYTLNRPDLTLAVCSALGVQPVRDLGAVA
>A0A0Q7CH79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. Root411|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAARQQLYARKPQFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKDMGVKRLVALRGDLPSGYGIGGEFLYASDLVAFI
REETGSDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
VRKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWVRLRLQGFGDDTASIKAFGLDVV
TDLCARLQEGGAPALHFYTMNQSAATLAVLERLD
>A0A1V5C610|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdus sp. PtaU1.Bin002|TrEMBL
MKPDSKLAVTMGGKEFIFTAEYLPVAGTEVTIDPKLFGSNVIAVNVADNHHGVSMSSLAA
SLALSRGGIEPVFQIITRDRNRIALQSDLLGAAFLGMKNVLCLSGFHQTLIGCSESANVF
DIDSVQLIDIVKKMNNGQLLDGTKIQGNFAMLIGAAANPNLKPLELNILRLSKKIAAGAD
FIQTQPVFDVDDFKVWLEAVRNAGLTDKTAILAGVMPLKGAAQAKGLADTYTDYIIPEAI
INRLDTAGGIEAQEKEGVKIAAEIINKLRDLPGLKGVHILSGGNESTVSELSGLSQ
>A0A1T4LJH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carboxydocella sporoproducens DSM 16521|TrEMBL
MDFRRKLLSGQFITTVELCPPRGIDCSKLLTTAKKIWGKVDAINITDNQRASIKISPVAV
CAILLKEGITPICQLTCRDRNRMALQSEILGAAALGVEYFLFMTGDHTLIGEDPKSKSVF
DLDSVQLMATAAQLNNGYTLNGKVLTGKPNLIYGGVVNPSLQCREAQMWKLERKVAAGIR
FVQTQAVYSVREVADFIEDAKRFNIRFLVGIIPLKSAAMARYMNKNIPGIKVPEKFIDIL
EKSKNPIKEGLRIAQDTINELKSISDGVHIMPMGTEEYLEELV
>R5AAY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:1013|TrEMBL
MKIKELLHRNDKKVTFSCEIFPPKKDIQFSGIFETVDSIQALGPDFISVTYGAGGSTSKK
TVEVASYIQNTHNIPALAHLTCCDSTKEDVRQRLEEMKQRGIENILALRGDLPKDYVPGP
YTYAIQLIQDIKAQGDFCVGAACYPEGHVECEHKEDDIAFLKEKVDAGCDFLTTQMFFDN
NVYYNFLYRVLAVGINVPVIPGIMPVINAKQIKRSCELSGSMLPPRFKAIADKFSDNPLA
MEQAGIAYATDQIIDLIANGVKYIHLYTMNRPKTAAKIMENLSHILR
>A0A643GAG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzomonas sagensis|TrEMBL
MKIIDTILPGKPFLSLEFFPPKERSEWPAFFHTVDRLKGVNPLFCSVTYGAGGSTHGDSL
EIVSRLKQKHGMETMAHLTCIGAHEDDVRTFLDQLTQAGVNNVLALRGDPPQDSTPDSSP
NRLLTHASDLVALIRASHPHVGLGVAAYPEVHPEAASAAADLAYLKLKLGRGADFAITQL
FFDNRIYFDFVRNARDHGITKPIIPGILPVVSLKVIKRIVSLCGTVMPPDFMAQLEEADR
RGGAAEVQKLGVAHARRQTEELLAGGAPGVHLYTLNRADAVLEVISGLSP
>A0A413B4R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides stercoris|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEKNGYHHAVELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTNEILKCKTDAEAQQVGIEWCVQQCKELMKHHIPSIHF
YSIGAVDSIKEVAKQIY
>U3GXY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium argentoratense DSM 44202|TrEMBL
MWLTYIASFPPTILAMSENLAQQTSGQSRTQLQLPILQAINLPAPGRVPFSVEFMPPRDD
AAENRLWRAAETFHDLGAAFVSVTYGAGGSTRQRTARIAHRLTQQPLTTLVHLTLVDHST
DELVEILKGYAEQGLTNLLALRGDPPGDPLGDWQACEDGLSYASELIDLVGQIPECSRFE
VGIASFPEGHYRAKDLEEDTFYTLAKLRAGAQYSITQMFFDVEHYLRLRDRLAAADPEHG
SKPVIPGLMPITSLRSVRRQVELSGAQLPAGLESRLERAAAGDPDKAAEEVRKVGIEVTT
QMAERLISEGAPDLHFMTLNFARATQEVLHNLGMAPAWGPDQGHDAVR
>A0A117LNU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium 38_7|TrEMBL
MHVAEILSKSNKTLFSFEILPPLKGGSFNDIYKSIEPLLEFKPAYINVTYHQEEVVYKDR
GNGLLEKKVVRKRPGTVGIAAALQYTCNIQVVPHMICGGFTREETENALIDLNFLGINNV
LVVRGDPDRSQKTFIPEPDGHIHSLDLVKQIVDLNHGKYLEEDLQNSTPTNFCIGVAGYP
EKHPEAPNKASDLRYLKMKIEAGASYIVTQMFFDNRKYFEFVNDCHEMGINVPIIPGLKP
VATCQHLYLLPKTFGIDLPDDLAKELEKCKTNQEARNLGIEWTIQQTKEIIAAHVPAVHF
YTMGRSDNIYQIAKACF
>A0A345Y656|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenobacter cavernae|TrEMBL
MSQNRTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPEFFSVTFGAGGTTRDGTLAAVLEIQ
GEGHAAAPHLSCIGSTRESIAAILQEYRNHGIRHIVALRGDIPSGMVGIGEFRYANELVA
FIREQHGDWFHIEVAAYPEYHPQAVSATADIDNFVRKVEAGADAAITQYFYNADAYFHFV
DAVRAKGVEIPIVPGLMPIANFSQLARFSDACGAEIPRWLRLKLQAYGDDIASIRALGLD
VVTELGDKLLTGGAPGLHFYTLNQAGLVSTVWQRLGL
>A0A3A8QEB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus interemptor|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTVEELAPLEPGFVSVTYGAGGSTRDRTV
ELVTHIKQHTGIEAMAHLTCVGHTRDELRDVLRRLGAAGIENVLLLRGDPPQGQTKFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLQHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRVGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVGALKGRS
>F8X4I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dysgonomonas mossii DSM 22836|TrEMBL
MTITELINKSDKTAFSFEILPPLKGNNIEKVYNIIDKLIEFDPQYINITTHHSEYLDQQM
PDGTVKRVNIRKRPGSVAIAASIQHKYNVTAVPHMICKGFSQEETEYALIDLNFLHVQNL
LLLRGDTKRLAPEQIYPNRNEYATDLQLQVNNFNEGIAADGSLFEKNATPFSYGMACYPE
VHEDAVSAESDIFYMKQKADNGAEYFVTQMFFDNQKYFSFVEKCREAGITQPIIPGVKPI
VLMSQLEVLPRIFRSSIPEELAVELRKCKTDDDAKEVGIEWGIKQSKELIEYGVPSIHFY
SLLATESVRRIAKEIY
>A0A381T7F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MEYQSLLHKKLLDGNFVYTAETTPPDSADQEVILTKTKPLKYIADAVNLTDSPGAKVHMS
ALTAAIILAQNDIEPILQLTVRDRNRLALQGDLVGASALGVHNILCLSGDDPKIGDQPET
IAVNDIDSLTLVATADLMRRKGKFPSGRLIEPPPKLCIGGAEVPTEGKPNTEKILNKIKT
GINFFQTQYVFDKKILKEYMKVLDDVGILEKTFFIIGLGPFTSAKSAKWMNNNLFGVNVP
DKIIKRLEQSNDEKEESKKICLELIHHFKEINGVMGVHLMGHNKEEIIAEIIQESRKNNN
>A0A484F7G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanimicrococcus blatticola|TrEMBL
MATKIIPRTISKNVSHPGVNMGSKGTFKEKLKSSQFLVTGEVSPPKGIDFSPAIENMKSI
QGFVDAINITDNQCATLHMSSMAFARLMIENGYSDPVMQMTCRDRNRIGLQADLLGAAAL
GIPNLLVMSGDHPKCGDHPTAKPVYDLDSVQLLRTINHLKKGYDFSGNNLTGAPDFCVGV
VSNADPNERLQIMKLEKKLSFDVDFIQTQAIFDIEKFKEFLEKVETDVPIIAGIIPIRSV
QMARYMDNNIPGISIPDEIHERIQAADDPVSEGMIISAELIMRLKPICRGIHMMPVGAHT
YTEKILKKAHVLE
>A0A382FEX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
QKKLSAIKPEFFSVTFGALGSSQNATFETVTKLLKNTNVPVSPHLTCVGIKKSQATELLD
KYIELGVNRVMVLKGDTPQVRFPYKNSRDKGDFHFANEMVEFIKEQYKGYFHIQVGAFPE
KHPQSKSFTNDIKFFVNKVNSGADSAVTQYFYNVDAYFSFVDEVQKFGVDIPIVPGIMPI
TNYEDLISFSKMAGAEIPSWIMNRLQLYKDDEESLKAFGQEVVSEMCLKLKAGGVKDFHF
YSMNRTEPVLSIAKYII
>A0A382EG32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MTKDLFRTFSNDFIYTAETTPAVATSLESSLKKVECLVGVADAINITDAPNCQPKLSSLV
AAGEIKKMGLDVILQITGRDRNRIAIESEVMGCLALGIDKILCLSGDKPPEDGPKAVNEL
NSSDIITLLKTMSDGHLSDDTEIQNSKNIISGCADSIYDHNNDGYSEFFLSKVNLGVTFV
QTQYCFDINLCKQYSEFIQNHNLDKKIYFLVGLGPL
>A0A382W453|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
ASALGVHNILCLSGDDPKNGDQPETIAVKDIDSLTLIATANMMRNERKFPSGRLIEPPPK
LFIGSAEVPTNGKINPEKILKKIKKGVNFFQTQYVFDEKILKEYMKVLEDVGILEKTFFI
IGLGPFASAKNAKWMNDNLFGVNVPNKILKRLEQSKDQKNESKKICLELIHYFKEINGVK
GVHLMGHNKEQVISEIIQESRI
>A0A1F9C3L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_64_85|TrEMBL
MRNILERMKESPLLFDGAMGTMIYERGVFINTCYDEVCLTNPKLISQIHREYVEAGADVI
ETNTFGANRIMLRPYGLADKAEAINRQAVRLAREAAGDSVYVAAAAGPCLRPDQIMPEEH
AAEVESAFAEQIGALAAEGVDLVVFETFTHLRELQVGARTAKRLGLPVLASFVLNERGET
AVGTRAETMARTLSADENVDLVGINCGVGPAGVFDALQAVLPVATKPVVVMPNAGYPRDI
AGRLIYLTSPEYFTEYAKKYIEMGVRGVGGCCGTTPAHIRMASRAVKSLSGVKKHVKVRA
YARQEPLVHVVPTGKKSRLAGKLIAGEKVASVEILPPRSCDMTEMLTKVRRCAEAGVDAI
NIPDGPRASARISPMIAALTILKEVGIEPILHYCCRDRNLISMQSDLLGGYAAGLANFLI
ITGDPPKLGDYPDVTGVFDVDAIGLTQVAANLNRGYDIGGNPISPPTGILIGVGANPCAV
DPEREIDRYFRKIDAGAEFAITQPVFDIEALLRFLDRVERHPRRIPVIAGIWPLVSYKNA
EFMNNEVPGVVVPREILDRMARCRSKEEGHRVGIEIARKIIEEISTRVSGFQVSAPLGNV
ETALAVLSG
>A0A1B1G3Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus equorum|TrEMBL
MSQFIDKLKNNILVADGAIGTILYSEGLDTCPEAYNLTHPEKVAHIHRSYIEAGADIIQT
NTYGANFEKLKDFGLEHKVKEIHQSAVKIAKEAAKDDTFILGTVGGFRGVKQEDLGLSAI
QYHTEIQVDTLVESGVDGLLFETYYDLEELTNIIKATKRKHDIPIIAQLTALNTNYLRDS
TEINTALQQVAASGADIVGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSQF
KYSDNAEYFGNVAQKLINEGVRVIGGCCGTTPEHIEFIKSSIANLKPVAQKNVIPITKYT
STTSKKTQPQSLTSKVKQRPTIIVELDTPKHLDTDTFFRNIKKLDDANIDAITLADNSLA
TVRISNVAAASIIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLLDINEILTITGDPSKI
GNLPGATNVYDVNSKGLTEIASRFNQGINTDGDALKTKTNFNIAGAFDPNVRKLDGAVKR
LEKKLESGMHYFITQPVYSTEKIKEVYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEEVLEQFEAVKDDKEKSKELSLKLSKELIDTVHEYFNGLYLITPFQKADYTLELAAY
SKSITSTKQEAIL
>A0A8G1PC11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus velezensis|TrEMBL
MGLLQDLKERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIADLGADITGINCRLGPYHMIEALTEVPIFRDTYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTDKEVKIRREEEVI
SVRNERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKQKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A3N5VSP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
QCETVRVREFGEMLTHSPAVDWVSITDNAGGNPQLAPIALGTPILYAGKEVVIHLTCKDL
NRHGLESQLWLLASQGFHNVLAMTGDYPMESFHGRAKPVFDIDSVALLEMITRMNDGIEV
AGRKPESASRRLDGTHFHAGAVTSSFKAQENTLLPQYYKLEKKIAGGAKFIINQIGFDAR
KSHELLAYMQWRGLGTIPLVGNVYLLSLPVAGLFHRRKIPGIVLTDALLEICKRQAASPD
KGRGFFIEFAAKQVAIYRGLGYRAVYLGGVHSPADLEKILQTERTFAPEDWREFARETGF
SQPGEFFLFEPDDGTGLCRPGVANPEWTKSLHSRERSHNVTPLYTLSKAFHSLMFDAGRG
LAPLGAKLCASALDPVQGPAWLRAVERVSKSLLYQCRDCGDCSLSETAFLCPESQCAKNQ
RNGPCGGTRDGLCEVHDYECIWARAYDRLKYEGRSHELLAHAPVVQNQGLRDTSAWANFW
LDRDHTSKPNTPNNNQNNNNP
>A0A1F9FUA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFCSPHIGHO2_02_FULL_44_16|TrEMBL
MKRDFLTTLTEKGILADGAMGTELYRRGIFINRCYDELCLSSPEIVKEIHREYVSAGAEL
IETNTFTANRLALSGFGLETKVREINMAGATLARAVAGENIFVAGSVGPVSWTKKNAGVM
DPKEIHDAFAEQIRALADGGVDAIFLETFTRLDELKIAYEAARSVTSLPIVCHLSLKYGG
EGEFEGLQPEVAAEEMDIWGADVIGVNCSDGPIGVFEALKRMTKVTKKPLSAMPNAGLPQ
MEQGRLLYMATPQYVAEYARRFAQLGVKLIGGCCGTTAAHIHEMKNFIKAIRVDDTGKTK
VIKDEQDKPYELHQVRFPSPIPVEEKSPFGALLGKKFSVSVEIEPPVSTDPSKALEGAML
LKEIGVDAINISDGPRAMARMSSTAMSLLIKERVGIEVITHYCCRDRNLLGIQMDLIGAN
ALGLRNLMLITGDPPKMGNYPEATAVFDIDAIGLIKFAANLNRGLDFAGRPIKGSTKFLL
GCGVNPGAVDIDLEVDRFARKVAAGAEFVFSQPVYEVERVEEFFKRIHSIPKIPIFVGIL
PLTSLRSAEFLHNEVPGMQIPKKVMSRMESAKTTETQRQVGMSVASEMLEAIHAMKEVTG
GAYIFPPFRSYAAIGDLLNVIR
>A0A382EYT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKISEKIADYIAQDKIYYSFEFFPPKTDFGMDNLYSRIDRMASLRPAYIDVTWGAGGSTA
DKTLEMCKTIQKYFGLEVMMHLTCTNMSVSSINKILIEAKENDLFNILALRGDPPEGSLT
WEKHADGFRYGVDLVRYIRKEFGDDFFLGVGGYPDGHQEQTDIDVDINFLKEKVDAGSDI
VVTQLFYDVDTFLLFRDKCIKAGIKVPIIPGIMPIHNYARFLKFTQFCKLSIPDSVSKKL
ESIKNDDSSVINYGIDQATAMCNKLIEENVPGLHFYTLNLEHSISEILKSLDLVSTTGII
KELPWRQSTLGDRKTSEDVRPIYWSNRPVSYLTRTENWDDFPNGRWGDITSPTFGELNQY
HAIRAGAKSDKVKARRKKIWGEPKSIKDIKDVFVSFCSGKINSLPWCEMPLAQESQQISS
NLINLNEMGFFTINSQPNVNGAPSEDAVVGWGGAGGRVYQKAYLEFFTSKDKLNALIKNI
KSTENISYQAINIDGDL
>A0A382UJV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MTYELIPLKNVHDQAAFLPENSTISVTCSPAKTIDDTLDLCATFADDGHTTIPHFAARMV
EDEAHVDSIVQRVNEQGIRKVFVVGGDADPRGPFTDAAGFLRSFLDRRPDIDVVGIGSYP
DGHSTIPEQALLDAQMEKQEMIVEAGLEGYMATQMCFDAETIRDWLRQRRSAGLTLPCHL
GVPGAVDRTKLLTISLRLGIGHSARYLKKNRASVIRLLSPGGYNPNKLVAPLSAVADELD
IVGIHCFTFNAVDTT
>A0A381R482|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MINFSLEYFPPNDQESLKSLIEQATVISTYSPHYMSITHTANPMVNNPTMQTVEILKKQL
AVRVTPHMTCINYSKTEIMQMVQDYSSLGVDSVVALRGNKKHNDRENEPYFDNSPEFISA
LNDNFDFRISISGYPEGHPERKGIIADFLYLKKKCDAGADEIITQWCFSNDAVLRYRDLC
ASRNINVPISIGILPISDMEKTQHFAKLCGSVIPREIKEAFNKSEGNDKATEDLGVRVAI
QQIENLSNEGIYNFHLYTLNRSEMTKRIIQHFAVPRIDEIARSEMRAS
>A0A108U894|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter capsici AZ78|TrEMBL
MLPISFEFYPPKTDEQRGQLDKTAIKLKPYAPSYVSCTFGAGGSTLNYTPETIRRLRAKH
KLDAAPHLSCVGGTRAEIRELLQLYREIGCKRLVTLRGDLPSGMASAGDLRYANELVEFI
RAETGDHFHIEVAAYPETHPQARDAHSDLENFKRKVRAGADGAITQYFYNADAYFRFVDD
VRAAGIDIPIVPGIMPISNFSQLRRFSDLCGAEIPRWVAQRMQAYGDDVDSIREFGADVV
ARLCSRLIEGGAPGLHFYTLNLSKPTLTVLSRIA
>A0A523VVY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium|TrEMBL
MKAGSNLEKILESGQFAVTAELGPPKGSDAEVVKKKGKLLGDYADAINITDNQTAIVRMS
SIACGVILTQLNLEPVIQIVCRDRNRLAIQSDILGASALGIKNVLCLSGDHQKFGNHPQA
KNVYDIDAVHLIQALKRMRDEKKLLEGDELTIEPKLYIGAVENPYADPYEFRVIRLAKKI
RAGCDFIQTQGVFDVKKFGDWMKTVTDQGLDRKVHILAGIIPIKSAGMVRYMREYVSGVS
VPDEIVTRMENAKDPRQEGIGICLEIIEQLKGIPGLHGIHIMAVAWESVVRVIVDKAGLT
PRPVV
>A0A2E3I9P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MVSYAQGIDALNQSLSEVKGINVSFEFFPPKTETMEKTLWKSVERLAPLKPKYMSVTYGA
NSGERDRTHEIVKRIQSETGIAAAPHLTCVDASRDELKQIAKDYWASGIRKIVALRGDLP
EGYTEHVSYASDLVALLRDVADFDIAVAAYPEKHPEAPNSQFDLLNLKRKAEAGANQAIS
QFFFDAEVFLRFRDRAAAAGIDMDIVPGILPVTNYQTLQRFAGFTNVHVPNWLHKMYDGL
DKDDQTTRNLMGASIAMDMVKVLAKEGIRDFHFYTLNRCELSYAICHMLGVRAD
>A0A497E485|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium|TrEMBL
MNFAEKLRSGKFLVTSEVGHLKGTEVDETLKEAELLRGKVDAFNVTDLQSSVMRLGSLAV
CHLLAERKLEPIFQITCRDRNRIALQSDL
>R5Y317|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:488|TrEMBL
MKITEILNNGKMSLSFEVFPPKTDTAFESVQQATREIAKLKPSYMSITYGAGGGTSKYTL
DIAEDIMKDYGVPTLAHLTCVSSSKATVQDRIFEMNKRGIKNVLALRGDIPSGMEADDRS
GWDHRYAVDLIREIKESGFDFCIGGACYPEIHPESSNQKEDIKHLKEKVDAGCEFLTTQM
FFDNNLLYNFLYKIREAGITVPIVAGIMPITNAKQVDRAIKLSGSFMPQRFKSLVDKFGS
DPLAMKQAGIAYATDQIIDLYANGVENVHVYSMNKPDVAQKIQSNLSDILGK
>A0A3M7NAZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetothyriales sp. CBS 132003|TrEMBL
MADGHITTLISSLPPDQPFFSLEFFPPKTQAGFTNLRSRLSRMATALRPLFVSVTWGAGG
STASKSIELAEVCQCQLGLPTVLHLTCTNMSKATIDDALAACKSLGVRNILALRGDPPRG
DEYREPADDEAQDGQFAWAVDLIRYIRHHHGDYFCIGCAGYPEGFPPDTQAQTDGGKQSV
EHDLPYLADKIDAGAQFIVCQFTYDLQSYARYEDLVRGYSHGGKKILQNIPILPGIMPIQ
NYSMLKRICKLTHVKVPNDLSAALEKVKHDDDAVKKVGVQALTDLVDGIKDRPARDIDRG
FHFYTLNLEKSCVSILDKAKLIPPLREVTPPESGSDSDAHNRVILSSPTPGTSPSTASVK
SRHEAPDRGVGIPASDPSREQKLLISKGHGSLGREATWDDFPNGRWGPAHSPAYGEIDGY
GPTLKVGPVTARKLWGHPKSSDDITQLFQRHVLGQLEAIPWSDEIDADDTGAPGPGVLRA
ETRVIRDELLAMIGKKHYWTLASQPAVDGVRSDDDTFGWGPQREGFVFQKPFVEFFCLKG
EWAQSLKPRLLRLPPEHVSWMKTDAAGKYESSEINAHPASSAAKIPADSGRGNAVTWGVF
PGKEIVTPTFIESESFRAWSDEAFAIWAEWRRCFPRGSDEEKFLDKMRHDCVLVNVVGHA
YRGGASGAGKALWDILLGD
>A0A662CQ64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquificae bacterium|TrEMBL
MRVRDILKERDLAISFEFFPPKSHQEEEALFENLERLKKWNPAFVSVTYGAGGSTHDKSL
GIAYTMKEQGLNVVAHLTCVEATKEDLARTLDWLAERGIENILALRGDPPQGEKTFRPVP
GGFQYAYQLVEFIKKGWDFCVGVAGYPEGHIENPDKEADLRYLKLKVDKGADFVVTQLFF
DNRFFFDFLKRAKAIGIKVPIIPGIMPITNLKQVMRFTQLCGATIPRALLEWLEEGNTPE
EVRRRGIEHAHLQCKELVERGIKALHFYTLNRSRATEEILTRLLGEPEV
>A0A6I5FGK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8374|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRIESVRPSFVSV
TYGAGGSTRSGTVRATQQIAADSTLTPVAHLTAVSHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A7J2PXL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon|TrEMBL
MVVAENKVYSKLGALIAKGEFVLTGELEPGKTCDLSHTIQEAREMAPYIVAANVTDSPLA
IVTINSMAAAHIIQRETGLECVWQLTVRDCNKVGIAGQIMGAQALGLHNVLSLTGDHTAL
GDCPESKPVFDLDSATLIKLVREMVDTGSINGHEIEHPPKFHVGCAANPNSDPMEAEILK
IGRKAEAGAEFIQTQVVYDIDMTADFLREIRKYNVPVFLGIFPMKSYGIAKGFDMFVPGV
DVPKDILARWKRVKTDVSDKKEQKETYDQLNYEFFKPFISELKSKGLLAGVHCMAVHYTR
IFSKLIDVIQS
>A0A8J3Q0T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planotetraspora kaengkrachanensis|TrEMBL
MTNHPFQIICEIEPPTRPDLKHVRHQIGTLSKVADTFLVPDNHIGRATVSSVAVAHEVEA
MGGRSIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPSSGSRTGELNVRAMIEEV
RALPKDSAFAGVRPFRVGTAAALRPLPAWKRAADFMFVQVSFSLEALLRWREANPVDVPV
YAGVMVLASEAHAQRLAAAIPDIDIPSELVEKVASDRLAGVEATCEQVLQIRDSGAFDGV
HLIPVARYREVAARLEHLLS
>A0A239BE75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerovirgula multivorans|TrEMBL
MKTLKRRLEENEFVITMEIEPPKSGDVKETYEKIKPLLKLVDAVNITDNPMASMRMSSII
LGYLVQRDLNTEAIFHFTCRDRNKLALQSELLGANALGVKNILTLTGDSPEQGDHPDATG
VFDMDSIGLAKVAHNLNNGKDSMGNPIEGQTDFFIGAVVNPTAEDIEKELDKLHQKIEAG
VGFFQTQPIFDIKKLEKFLKKVDNIQVPIIYGLMPLKSVKLAKFLNRKVPGIHVPDELID
RLEIKGREAGKEIAEELLQEMKKIVPGVHIFPMNDNELIEELLKNNLK
>A0A1C7BDB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa BL04|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A397JQK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diversispora epigaea|TrEMBL
MKITDKINTLESDQSYYSFEFFPPKTDEGLANLYNRLKRMSLLEPLFASFTWGAGGSTID
KTLEMCTTSQGLYGFETCMHLTCTNVVREIVENALKEAKNAGIQNILALRGDPPRGHEYW
TSCDDEFTLAIDLVKYIRKKYGEWFCIGVAGYPEGYPDSTDKEQDLKFLKEKVDAGANFI
ITQFFYDVDSFIEWEKKCREIGITVPIIPGIMPIQGYNSFRRITNLCKVKVPGEILNALE
TFKHDDQAVKEYGVSLTVSMISKLLEHKIRGFHICTLNLEKSVRLILEKLKFVQTEEERA
MRRLNRRRSSAGFIPNDIIRQEPDGSVPAAKPIIWKEQNADYIGRPEDWDNFPNGRWGDA
RSPAFGELDGYGVSLRIPSDLALKYWGEPKTINDIIRVFKSYINCEISALPWSEEPLLKE
TDIIRPNLLKINELGYLTISSQPAVNGAKSSAPDFGWGPKGGFVYQKAFVEFFVSPEMFE
KLTKSIDDNVWVTYYAAKRNEEFETNIKEETPSAVTWGVFPGKEIIQPTIIEEVSFNAWK
KEAFALWSEWEYLYPKGSPSQTLLKNIGDNWWLINLVYHNYVDTDGIWNIFYKI
>A0A0R2D0L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus aquaticus DSM 21051|TrEMBL
MTTLDQLQNLKPHFISVTCSNNKSDFEKTTLKLADYINNTLDIPAIAHLPAAYLSANQVK
RILTELDSLNIHQVLALRGDIIPRIPRKNDFNYASDLIKFVRAQEPSFEISGACYPEIHP
ESPNLVSDIHYLKQKVDVGCNQLITQLFFDNDKFFAFKENCALAGINIPIIAGIMPITNR
KQALRLIKTTSAHLPKKFMAIFDKYENDPESLRTAGLAYAVDQIADLITRGAAGIHLYTM
NHAETALSIQKTIGSLFKTNNKQLNNQ
>A0A239CYE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerovirgula multivorans|TrEMBL
MPAVNSKQIRRVVSLCGAKIPHDLEALLVKYENDDASMFSAGIDYACKQIDGLIRHGIDG
LHNYSKT
>A0A0P7X9V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium HLUCCA12|TrEMBL
MSAPQVSFEFFPPKSLDASFRLWDTVRMLAPLSPKFVSVTYGAGGTTRKLTHEAVTTIGA
QFGLNVAAHLTCVDATRAETLEIAKSYASAGVREIVALRGDPPKGQGRFQPHPDGFANSI
ELIEALRTVGDFTLRVGAYPEPHPESADTAADVRWLKRKFEAGADSAITQFFFEAETFLR
FRDACARAGIDAERVIPGIIPIENWQGIRKFALATGTSVPAWLDDAFDKARRDGREELLA
TALCTEMCDTLMAEGVRDLHFYTLNRAHLTRDVCHALGVTAQVQLENVA
>A0A369UR46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella tabacisoli|TrEMBL
MPPISFEFFPPKTDEQRTQLDRTAKALKPLAPDYVSVTFGAGGSTLSYTSETVQHLHREH
GLDVAPHLSCVGGTRAELAALLDTYRSAGYRRIVALRGDLPSGMATPGDFRYAVELVRFI
REHSGDHFHIEVAAYPEMHPQADDALVDLRHFKAKVDAGANGAITQYFYNADAYFRFVED
VQRLGVNVPIVPGIMPISNYTQLRRFSEGCGAEIPRWIAKRMQAHGDDAESVRSLGAEVV
AQLCRRLLDGGAPGLHFYTLNRAKTTQAVLEQL
>A0A1C3U098|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium hainanense|TrEMBL
MSSRSESRNDGIRISFEFFPPKSEEAEQQLWNTVEELSDWDAEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLAAGVRRFVALRGDPPGGVGAAYQP
HPGGYANAAELVQALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKAENGADRALTQF
FFDNDAFERYHDRVRAAGIEIPVVPGIMPIQNLTQLKRFAGACGTNIPSWLDERFDGLEE
NTEERARVAADVAAEQIQNLMRRGIHEFHLYTMNRSALVSAVLERLGLERKVDARAGAAA
>A0A8E2DUX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Obba rivulosa|TrEMBL
MKISKKMEAALKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTCEMVKTCQSLIGIETCMHLTCTNMPEEKVDIALREAKQSGCRNVLALRGDPPMGKDE
WEAVEGGFTHGIDLIRHIRKEYGDYFDIAVAGFPQHIELPPEECDLEMKYLKDKIDAGAN
FIFTQMFYDVDIFIKWVHAVRAAGITVPIVPGIAPIQTFNGFIKSTALSKTTIPQPLLDA
LEPHKNNDEKVREIGTKLVADMCRRILKEDIGIRGLHFYTMNLERGTRMLLEELNLVPRV
ETVKPLPWRPSLTPNRRSENIRPIFWANRPRSYVHRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEEALKLWDTPTTINEIRELFKKFCSGQLKALPWSDEAPASETTVIAPQLA
KLNELGFLTINSQPAVDGARSDDRVHGWGPSNGYVYQKAYLEFFVSPHLLDALLPYIERD
VNITYYVINKRGDLRTNNHSDGPNAVTWGVFPGKEIIQPTVVEAISFMAWKDEAYELGRQ
WAKLYEPDSPTRKLIADIMDTYLLVNVVHNDYKRPDAIFEPFYKAGAEYSA
>A0A8J0TCD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenopus laevis|TrEMBL
MVNANSSDSGTASCSSEENSKESSRCSTPVLDIERHERLKDKMKRRIEAGDRWFSLEFFP
PRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNFCGLESIL
HMTCCTQTKEDITKHLQKAKHLGLKNIMALRGDPTGEEWEEEAEGFNYAVDLVKHIRHEF
DDYFDICVAGYPKGHPEADSYDQDLKHLKEKIDAGADFIITQLFFRSETFLTFLKDCRAI
GITCPVLPGIFPIQGYGSLRQLVKLSKLEVPQEIMDIIEPIKDNDAAIRNYGIDLAVSMC
RELLDSGLVHGLHFYTLNREVATIDVLKRLGMWKEDPRRPMPWAMSAHPKRRVEDVRPIF
WASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGDLKDYYLFYLKSKSPREELLKMWGQELT
SEESVFEVFTHYISGEPNPNGHKVTCLPWNDDPLAPETNLLKNELQKVNKRGILTINSQP
NVNGKPSTDPIMGWGPSRGYVFQKAYLEFFTSSEMVSALIKVLKRYEPRMNYHIVNVHGK
NITNAADLQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKFYEEESPSR
MIIQYIHDNYYLVNLVDNDFPLENCLWQVIEDTFKEHDSPTDQ
>A0A0M9G171|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptomonas pyrrhocoris|TrEMBL
MVKIAEAIKQANENGRYFVSFEFTVPTTEAGVITLYDRIERLAALDPLFCGITWDEGGRS
AETSIEVASTCQSLLSVNHQVNLTGYASEPEEMLKWLTVLKSKGVCNVLITRGASANKTI
STTRASSCTTNKSKPAAHGTADDADAMAVGSAPSSPPASPAFPHAVDLVRFVRQHFGNFF
GIAVVAFPEGEGDSADNVARQAEIEERELRFLKEKMDAGADYIITHSVFDVNVFDHFCQQ
CRRHGIRCPILPGVLPISQLRQLNAFGLRRLAGTADLVTKMEAVKGSESETRRVVVAFYQ
DLVKQLLNRGCGGVYLFTMNADYLLVAILKGIEVATHRMFPWRPSENEERRRQETVRPVH
WSSRVTSYMVRTAQWQDRKTDKWNPVSGSHHGSALALGEVGGYHARLLLRSRAKRCTQFL
VIQGMPEIQTALSALSRIFVAFLDGNGTLPWADELSGETVYVGEHLLKPLNARGLYTINS
QPHVNGAPSSHKVVGWGPGDGCVYQKSYLEFFCPLTMAQTVFTTLERYPSLQYMAMDAQG
NMVHARWRMDDDSGKDSEASPPQAAEHDPTVASPTQQPHDRMSLFGVGVTAVTWGVFPGR
EVIQPTIVSVDSFRAWVGEAFDLWAAPFPGHDVPAVVRYIQSEWVLVSVVDNTYQETPTP
LENAVVEICSKIPPLIPVDLSQPRQRATSLTFPAKTGVESSTLGTFATST
>A0A7Y8MFU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilaceae bacterium|TrEMBL
MSAALMPALAHPQTLLADWSLEMTAKDADALADASDAIPAGAQVSLTFLPDEDFDQRIEA
AVLIRRLGLEPMPHLSARRIASEADLDMYLDCLTACAGVDRVFVVAGDPPRPIGPYEDAL
ALIRSGLLAKYGVRHVGIAGYPEGHSAIPAAKLAQAMRDKLAALADLGHEASICTQFGFD
AEPMLEWVARLRDAGVSAPVRLGLAGPASVKTLLRFAARCGVGVSAKVMAKYGLSMTRLL
NNAGPAPLIDALERTLDPAVHGDVRLHFYPFGGLAKTADWVRDFTASRVC
>A0A7K1RB08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium vitis|TrEMBL
MAHTSSNKDQARPFKLSFEFFPPKSEEMEAQLWATVDELTGWEPEFVSVTYGAGGTTKAP
TLAAVRRLLAETPLATASHLTCVGATREEIAQVVEDFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGFENAAALVKGLKELGDFEISVSAYPEKHPESADLAMDLDMLKRKVDNGATRALT
QFFFDNDIFERYLDKVRAAGINIPIVPGIMPILNLTQLKRFAGMCGTSVPAMLDQRFEGL
DDKPVERASVAATLAAEQIADLQGRGIDEFHIYTMNRAPLVNATLERLGLQRSDTVAASR
AGVIA
>A0A8J3LSQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planosporangium flavigriseum|TrEMBL
MRSSGPTFSFEFFPPKTPDGERLLWQAIRELESLKPSFVSITYGAGGSTRDTTIAVTERI
ATETTLLPLAHLTAVNHSVAELRRVIGNYAEAGIHNMLVLRGDPPGDPQGEWVAHPEGLQ
YADELVRLVRSSGDFCVGVAAFPEKHPRSPDLETDIDYFVRKCRAGADFAITQFFFRWED
WARLRDGVAARGCDVPIIAGVMPVTNVKSIETMAKLSGAAFPADLAERLRAVADDPAAVR
EIGVEVASELSARLLAEGAPGIHFITLNRSTATREIWHHLGMGATPANR
>A0A8E1Q255|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas helleri|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKDDLRGLLTQYKGAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDISNFVRKANAGADSAITQYFFNADSYFR
FVERVRAAGVMIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDATSIQKFG
EQVISEMCERLLDGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A0F5PNB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldanaerobacter subterraneus subsp. pacificus DSM 12653|TrEMBL
MLKNEKLCNKLKEKKFVITVEISPPKGIDVTKTIEEARKLKGVADALNITDSPMANMRMS
PIALAHILQDHLNIETIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDNPSLGDTPQ
ARGVYDVDSVGLLKIIKALNSGFDYNGNKLDYPTSFCAGTTANPNDLRDEAIEKLHVKVE
AGAEFIQTQPVYDEEILFKFLDKVKDLKVPVLVGILPLKSYKMALRLMEKVPGIEIPEKV
IKRLQHGGKEEGINLSAEFIKNIKSEVAGIHIMPMGSVDFVFDIISKVEGIAISAKKAET
K
>A0A1C7DUH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus halocryophilus|TrEMBL
MGLLDELKTKILTADGAMGTLLYSYGIEYCNEELNLQRPEIVEKIHLDYIKAGADIIQTN
TYGANALKLARYGLESQVAEINKAAIEIANRAAAPGGQFVFGTIGGIRGIRKSDASLQEI
IAMVDQQATYLLEGNPDGLLLETYYDFEELAATVKHLKSITNTPLIAQVSMHDPGILQNG
MSLNDALHQLESLGADIVGVNCRLGPHHTIQAFEEVTLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGRAALLLREEGVRLIGGCCGTTPKHIEAVKKHLGQLAPIVHKEVTERKPIV
IREAEALEVKPLHEKAKTERTIIVELDTPRHLDVTKFLEGSVALKAAGVDAVTMADNSLA
SPRISNMAMGSILKHTEDIRALAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKKLNEGISFSGKSLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIESGADYFISQPVYTKEKITEIYEATKHLETPIFIGVMPLTSIRSAEFLHNEVPGI
KLSDDALARMRACGDDKDLATQEGIQIAKELIDTAAELFHGIYLITPFVRYDMTVELIHY
IRQLDQQKESDHSHVQASY
>A0A2L1HQN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SWI6|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSAERFAAMEAIMDRAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFGKPLPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
IRYLESVTALQIARQACPHWLLGAALNPFKYREEEGGAQYFKAEKKLAAGADFFTLQLGF
DADKHQEAIRWMSRQATPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDILEAEAAQSK
AFAQARSIDRLALQIIGTRLMGYAGVHLSGIHALKQLLALEARIEHWQGQIHSLQQWAPA
WQASWQMPGLPAVVFHPPQAGWRQGESRVAASGREKLRYHVMHGMHRLLFSRRNWLSKAF
GWAVRQPLWTTRLGARVLHTLERGVKRPLVGCDTCGHCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLSERLIPCIEVQTRHRSSWPQWFEAQAP
TRLNPRPAPRTQPES
>A0A3N5Z4B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sediminis|TrEMBL
MVSYAQGIDALNQSISELRDIDVSFEFFPPKTEAMETTLWKSVERLAPLKPAYMSVTYGA
NSGERDRTHEIVKRIQQQTGVVAAPHLTCIDASRDELVNIAKDYWDSGIRRIVALRGDLP
PGTTEKPAMYASDLVELLRDVADFDISVAAYPEKHPEAPNSQFDLLNLKRKAEAGATEAI
SQFFFDASVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLLRFAGFTNVHVPSWLHKQFEG
LDESDQTTRNLLGANIAMDLVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRATA
>L0DDE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10)|TrEMBL
MHILDIFKAHPTTFSFEFFPPKTDKSSSDLFRNIEQLQVLQPSFVSVTYGAGGSTRERTH
DLVIRIQSETNLTAVSHLTCVCHGMDDLASILDRYASSGIENILALGGDPPRNLVDYNRA
NDAFQYADGLVAFIKSRTSEANPRGFGIGVAGFPEGHPATPNRLNEMDHLKRKVDAGADY
ICTQLFFSNADFYDFRERCEYAGIKVPILAGIMPITRDTNISRMAELALGARFPARLLKS
LDRCGDDPEARERVGIHWATEQCRDLLDNNVRGLHFYTLNRSDATRRIYENLGVKDSVGL
RQS
>A0A061AF75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosporidium toruloides|TrEMBL
MVKISDKIKKAEREGRPWWSFEFFPPKTPEGWVNLYDRIERMQQLGPIFVDITWGAGGST
SEATTNFVKTAHSELGLETCMHLTCTNMPVEMVDKALKEAYDSGCRNILALRGDPPRGVE
EWKPTEGGFNHAIDLVKHIRKNYGDYFCIGVAGFPEGHPQSESPEAEIRHFKKKVDAGAD
IVFTQMFYDADVFIDWGRRLRAAGITIPIVPGIMPIQTFAAFKRRTDFAGTIVPKELWDL
LEPIKDDDAKVREVGTEYVADMCRKILNADLGIHGIHCYTMNLSRGTEMLLEEMQFVPTA
DRVKPLPWRLSLTQKRRAETTRPIFWSNRQKSYITRTRDWDEFPNGRWGDASSPAFGDVD
ALLLALPHKPQDAIKLWGKPHSLGDIAALFARFCRGDLKSLPWSDQPAAKETTRIAEQLA
RINELGFLTINSQPRVDGAPSEDPAVGWGPIRGYVYQKAYLEFFCPPELVEPLLELLGDT
PSVTYHAVNKQGDFRSNTAPGPNAVTWGVFPGAEVIQPTVVDSTAFQAWKDEAYELGWQW
AQLYKETAPETYEVISRIFSDFHLVNIVFNDYRNNDEDAIFKPFFELAHQKGLSVANGH
>A0A4R5AWC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium caseinilyticum|TrEMBL
MKVTQHIEAAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKLGGNDFAVDLVKQINQLNCGKYLHDVMDVDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLINAVDQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIAGKVF
>A0A1E4S9U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyberlindnera jadinii (strain ATCC 18201 / CBS 1600 / BCRC 20928 / JCM 3617 / NBRC 0987 / NRRL Y-1542)|TrEMBL
MSIREKIDSLKEDDVFISLEFFPPKTESGIRNLLARMERMSAMNPLFVTVTWGAGGSTAE
KTLSLVQTCQREMDLTTCMHLTCTNIDKSIIDDALAKAKAAGVRNILALRGDPPRGEEYF
VPNSADFSHAVDLVKYIKKQYGDWFCVGVAAYPEGHCEGADSANQSVAKDLPYLKEKVDA
GADFIITQLFYDVEKFLTFEQMVRNNISKDIPILPGLMPINTYQLFHRAAKLSHASIPRS
ILDRFPESIQNDDDKVKSVGVDILKDIIHEIYSRTNGRIRGFHFYTLNLEKAIAQIVEKS
SLLNGMIENDDEDVIMDDDEDHIATLKTARSSSVSNRVLVDKLQRDPVDFQDASDFKLQA
PSKKAILAISSGEGTLGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSLKIATERAYELWG
YPVDLKDVSNVFVGYLEGKIDALPWSELGLSPETAMIQEELIQLNERGYLSLASQPACDS
ARSDDKIFGWGPKGGYVYQKAFVELFVSRDAWLNTLKPKLLSNEKAGYYLGDSRGGFESS
LDTKSSNAVTWGVFPDREILQTTIIEEESFKAWRDEAFSIWLEWAKLYKKNTPSYKLLQQ
IHDDYLLVTVVCHDYRNETGLWDLLLE
>A1BH63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium phaeobacteroides (strain DSM 266)|TrEMBL
MLVREILNSTSEPVFSFEFFPPKKEEEWNTLFATIASLTSLNPSYVSVTYGAGGSTRSKT
HDLVTRIQKETGITVVSHLTCVCSDREETSSILENYLENGINNVLALRGDKPQGVATLAE
AIKDFEHAADLIRFIKIRFPAIGIGVAGFPEGHPETPNRLKEIDYLKEKIDAGADYIVTQ
LFFDNRDYFDYVERCAIAGITVPIIAGIMPVSTKKGMIRMSELALGARIPAPLLKQVLES
DSDRDVAEIGIDWATRQVQELIDQQCKGIHFYTLNLADATLKIFRNIRQ
>A0A437UCQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium columnare|TrEMBL
MKVTEHIEKANGKTQFSFEILPPLKGQNIQCIFDGIDPLMEFNPPFIDVTYHREEYEFKE
LPNGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKAEKEGNAYASELVTQISNLNKGIYLDDDLQNTNATDFCIGVAGY
PEKHMEAPSMDSDIYFMKQKIKNGADYIITQMFFDNQKFFEYVEKCRNAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNEAVKQIGIEWCIQQSKELVKAGIPVLH
YYSMGKAENIKAIAGEVF
>A0A849N7P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseicella sp. DB1501|TrEMBL
MSNMEDRGSTLERWLTPPRVATLPWPSELAAPKLSFEFFPPKNAKLEADLWACIRRLEPL
APRFVSVTYGAGGSTRARTHETVARLGRETSLTPAAHLTCVGATREEVDEVARTYWQAGV
RHIVALRGDPPAGAATYEPHPGGYAQAEDMVRGLRRIAPFDISVGAYPEVHPAALSPDAD
LDFLKRKIDAGANRAITQYFFDADVYLRFLDRCHAAGITVPIVPGIMPVTNFASVKRFSA
MCGASVPDWLARLFDGLEEDEATRRLVAATVAAEQVRILQANGVDEFHFYTLNRPDLTYA
IAHILGVRPA
>A0A7V8AGW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MKIASMLSSGGRTFSFEFYPPKKEEDIPALKSAISELRELGPDFVSITLSQKYMPTWNFA
SISNTLALSGVLRHEFSLEVMAHLTTAIIRDQQTLEETLKLVKILGLENVLALRGDLDPG
REGERAFAYASDLVPAVKEGGDFCVGVAAYPEKHPEAPSLAEDVRRLKQKMDAGGEFAIT
QVFFDNAAFFRFRDAAAAAGVTAPIIPGLMPLTSLRQRDNFVAGQGISVPAALSAGLEKH
GGDKEALFAFGLDYAVNQAEELLAAGVPGLHFYTFNKSKATREVFSRLNPARRRARNNEP
PAHQVPGAMPPGPGTDCGKSRPDPARSRLV
>A0A4Q2SN51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides zhouii|TrEMBL
MTHGRDLSMSERLARGDRSFSFEFFPPKDEAGEEQLWRAITELEPFGPTFVSVTYGAGGT
TRDRTVAITERIARDTSMLPVAHLTCVGHTTDEITSILDDLRAAGVTHVMALRGDPPTGP
GTPWTPTEGGLTYANELVALIHERDDMRIGVAAFPEGHVDAADLDTDARVLRAKYDAGAE
FAVTDMVLRASDYVGLVERAKAVGADLPIIPGIMPILNLRSMERMVEFSRRQLPQEITDR
LSPLAEDPAALRAEGIAIATELCEALLDAGAPGLHFYTLNRSKATREIFANLRITV
>A0A1S3GW26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dipodomys ordii|TrEMBL
MTPRPPLCLGQGYSSLRQLVKLSKLQVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCREL
LASGLVPGLHFYTLNREVATTEVLRRLGMWNEDPRRPLPWAVSAHPKRREEDVRPIFWAS
RPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPAEELLKMWGEELTSEE
SVFQVFAHYLSGEPNRQGHRVSGLAVGSGPPAQCLAV
>A0A838IA64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MRIDRILGNRRPVFSFEFFPPKTDEGRQTLEGTLADLKEDTPDYVSVTYGAGGTTRERTV
EITKWIKENLGIEAMAHLSLVGEDEARLVEILEEIQAAGIENVLALRGDPPRGETEWKPH
PGGLKHSVELIRLVRERFDFSVGAACFPEVHPEAPDRESDLRYALEKVEAGAGFLITQLF
MDNELYFDFVEQARDAGIGVPIIPGIMPITNFGQIKTITGMCSATIPAELERELEGRADD
PEAVAELGVAYATLQCSDLLARGAPGIHFYTLNRSPATRAILAALRAAHPWTRATAPV
>A0A7X7TUQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MKISNILKKKRSLSFEFFPPKTREDFTVFISTLKELKKFKPDFVSITDSDICGKTKHIAL
SRILKEKLKLNVLIHLTCVNNTEKEIEYSLRAIKKIGLDNILALRGDKRNFTRTTKSFIH
STDLIKRIDKNLFSIGIAMHPEGHHRGSLERDIYYIKKKIEAGAEFGITQLFFDNSSFFR
FRDRVKKAYPNIPIICGIMPVTNYNMLSNICKKISCITIPEKLRDIALKYRDKRDEFFKH
SIDFSINQVKELIKNDIEGIHFFTFNRALGTKKIIENIKLI
>A0A7W0X7P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MKLRDLYARPGVTLSVEFYPPKSDQGDEDLLREALILKSLHPFYCSMTYGAGGTTREKSV
DLVTRIQRECALTTMCHLTVTGQSKAEVRGVLEKLKTNGIENIIALAGDPPQGAAAEWVP
HPDGFHYSIGLVREAVAHGRFSIAVAGFPEVHPRAGSRAADLRYLKEKVDAGADVVITQL
FFDNDDYYRYVDDARKLGIRVPIAPGLLPIQS
>A0A849II70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dormibacteraeota bacterium|TrEMBL
MFPAAERSAELSMPRHAQLEPVRQALAQLAQAVGVVGLTDNHMGRPRLSPLAAVPACLAH
GLRPIVHLSCRDRNLLGLQQQVLGAAALGAAGVLVVRGDRNQATVDTGISVVDVLARIPT
WAQPQDLLRGAVVNPFAERPRELRLLARKVAAGIDFVQTQMIFDLDAFDSFLEDARDVLP
PRVAIFASLGVIRSARSLAFVRASLPALPIPEPMAQRMAAGEGVAVAAEIATEIGHRPGL
RLHLITLGAEHYAVGISRAFTAARAADVGAAG
>A0A5A7MXR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Iodidimonas gelatinilytica|TrEMBL
MSQLRSLSPSLFADRLADTDVSFEFFPPKSEAMETRLWAAIKTLEPLAPRFVSVTYGAGG
STRERTHNTVRRLIRETTLAPAAHLTCVDASREEIDAIVRDYRDSGVRHIVALRGDAPDP
SKGYQPTPGGYANAAELVAGIRAIGDFEISVAAYPECHPESASLVADLDNLKRKVDAGAT
RAITQFFFEADQYFRYLDHVRSYGIDVEITPGILPVTNVKQLKRFADGCGASVPRWMADL
FEGLDDLPQTRALVAATVAAEMCRRLQAGGVNSFHFYTLNRDELTYAICHMLGIRSSTHG
TSQEKAG
>A0A521ICE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MNTEISIEFFPPQTAEGADKLRATCAKLAVLKPAFFSVTYGAGGSTRERTFAAVKEIAAA
GHEAAPHLSCIGSTRDSIREILQQYADAGIRRIVALRGDLPSGAGAAGEFRYANELVQFI
RAETGDRFRIEVAAYPEWHPQARSPKDDLLAFKRKADAGANGAITQYFYNLDAYLYFVEA
VRKMGVDIPIVPGIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDAESIRAFGLDVV
TRLCEKLIAAGAPGLHFYSMNMAGPTTEICRRLGLGG
>A0A536SQH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MESQKRHPRTFSFEFFPPKTPEGMERLRQTWKQLAQLKPRFFSCTYGAGGSTRDRTLETV
LEIQAAGHKAAPHISCIGATRADIAATLELYKSKGIDHIVALRGDLPSGAASAGELRYAS
DLVAFIREKTGEHFHVEVACYPEFHPQARSPREDIANFKRKIEAGADAAITQYFYNLDSY
FRFVDDCEALDIDLPIVPGIMPIGNFSQLARFSDACGAEIPRWLRLKMQSFGDDAASIRS
LGLEVVTDLCDRLLSAGAPGLHFYTMNQAGLTSTI
>A0A536YP46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MESQKKHPRTFSFEFFPPKTPEGMEKLRATWKQLAQLKPRFFSCTYGAGGSTRDRTLETV
LEIQAAGHRSAPHISCIGGTRADIAATLELYKSKGIGHIVALRGDLPSGAASAGEVRYAS
DLVALIREKTGDHFHIEVACYPEFHPQARSPREDLASFKRKIEAGADAAITQYFYNIDSY
FRFVDDCEALGVDLPIVPGVMPIGNFSQLARFSDNCGAEIPRWLRLKMQSLGDDVASIRS
LGLDVVTELCDRLLSAGAPGLHFYTMNQAGLTSTIWQRLGL
>A0A2V1MYZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Levilactobacillus bambusae|TrEMBL
MPTTSFSLEIVPPSRPEAISAYQEMLVELPALAPESVAVTLGAGQAETTKEASLTALGII
QNQLMLPAVAHLPGLYETKASISQFLDELASRRVTKVMALRGEVQPEKAIGDFPHASDLA
NFINRFGSFDIVGASYPARHPESSSWVAELLGLQHKVDAGMSQLITQVFFDNQIYDNFIH
RIRQAGINIPVTVGVMPLLSQHLVDNLTHNMGIPLSHRVNQLITKYGNDPQAFRQAGIQY
AIDQINELLAMGVEGIHLFTMNDADATKQIKSATFG
>A0A377IZM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus pittmaniae|TrEMBL
MSYAKEIDTLNQHIADINNKKINVSFEFFPPKNEKMENML
>A0A3D1N0B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MKISEKLKKQSRVFSFEFYPPKKEEDIPFLKKAVEELKTLSPDFVSITQSPTALSGLNFA
SLSSTLALSGVLKHEFSLEVMAHLTCVTLKNREMLDEAVKLLKIFGLENVLALRGDSAAV
EFEKPIFSRACELARELKSRGAFDIAAACYPEKHPEAVSLEADIDNLKRKMDCGASFAIT
QLFLDNASYFSFREKCLARGVTIPIIPGIMPVTGLSQLTNFAERIKVKIPARLLAALEKL
SPADAEGGPETKAAIRDFGIAYAAGQCRELLKNGAPGIHFYTLNRSKATSAVLNLVKKEI
KGTANSI
>A0A093RD36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium betavasculorum|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWQSGIRHIVALRGD
LPSDGGKPEMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTSVFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A1B7T8Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hanseniaspora valbyensis NRRL Y-1626|TrEMBL
MSSLLNISDTYFSQHASPPNLNTKTKPSISLEFFPPKTKIGLNNLIKRIERLTIALQPIF
ITVTYSQLNSAKTLELIKLLTENSNFKNVNICCHLTCTNHSISLIDEALETCKKLGIKNI
LALRGDPIDIEDTNNNNNNGNIQFKYAVDLVRYIKQKYGDTFCIGVAAYPEGHYNNDYNP
VTKNYTSSQNYGQDLIYLKEKLDAGASFIITQLFYNADKFLSFYNAYKEMIPDYKKYLMI
PGIMPINNFMIFNRATKLAHVDIPKELIDRFPVDIRNDDDQVRNIGVNIMIEIIERIYNE
TNKEVNIFHFYTLNLEKSIAQIISNSSLLSQILEDSDDEDEDDEDEDEDSEVEIEVEEEE
EEEQQQQHDYSYYESAIVDDPYLRVLQNTKKISHTSEEIKIALQRDSDMEEDEDIVFDNN
DDDEELEYEANEKEIAPSDGHYATKTPDFKNPVVAFKRKRSRSSQSSMTSGLLLSVLNNT
LKKPFKQHKKLIKEISKGTNPQLGKTILWDEFTNGRFGDSRSPAFGEMDGYGPTLKVAPH
KALQYWSNPTKIENLAEIFEQYLLNSIPVLPWCDLVGLSPETGLIQEQLLELINDCQYLT
TSSQPSCNGISSNDKIFGWGPLNGKVYQKAFVEFFIKKEKWDKLKQRLDNDERFGYYCGT
PTHFESSLSQQDNIKKNNSIGNGNVDGSSCVVTWGVFSNSEIQQTTILEEESFKAWCEEA
FQLWKEWAKIFPRDSESYKFISSCYDDFYLVEVVYHDFSDFDGLWDFLLYNDDIDVEMN
>A0A846FCL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanothece sp. SIO1E1|TrEMBL
MKVTEYFEKAAGQTLISFEVLPPLKGGSMKAIFDTLDPLMEFKPPFIDVTYHREEFLYKK
RDSGYYEKTSIRKRPGTVGICASIMHRYGVDAVPHLICGGFTEEDTENALIDLNFLNIKN
VLALRGDARKFEGKFIPEAGGHAYALDLIKQIDDMNKGKYLDSNIENGEKTDFCIGIAGY
PEKHFEAPNMGLDLQYTKAKIDAGANYIVTQMFFDNKKYFEYVKQCREVGINVPIVPGLK
PVTKLYQLSSLPRLFHIDLPDELVNSITKAKNAEGRRQAGIEWCAQQSKELKEAGVPCLH
YYTMGDSDTIRQIVEKVY
>L9X8S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronococcus amylolyticus DSM 10524|TrEMBL
MSGEIQSIPTAEGMVELLEEPRFELMPFESIDEQLGHLPEGSEIAITTSPTLGLEATIEW
SERASERGYEIVPHVAARYVEDQDHLEEIARRLTEAGVTDIFVPGGDREEPAGEFESALE
LLVALEELPYSFAEVGITGYPEGHAFIDDETLAESMAEKEPYATYIVTQLCYDPDAVIEW
VEEIRARGVELPVEVGIPGVMKYQRLLGISKKVGVGDSVRFLKKTSGIVGFVRQLVGSRG
TYSPDTLLEGLAPYATDPRYDIRGVHIYAFNQVPDLESWRAETLEKHR
>A0A7Z9BRC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktothrix paucivesiculata PCC 9631|TrEMBL
MNRFRTACQTLDEFIVTAEVAPPKGADPSHMIEMVRLLKGRVHAVNITDGSRAVLGMSSL
AASIILLHHGVEPIYQLACRDRNRIGLQADLLGAQALGIRNVLALTGDPVKAGDHPDAKA
VFDLESVRLLQAIDKLNQGKDWNNKTLPDGATDLFPGAAVDPQSSSWSGLKSRFERKIEA
GAQFFQSQLITDFDRFDQFMTEIADSSKKPILAGIFLLKSAKNARFINKYVPGVCIPDAI
IDRLEQSKHPLEEGILIASEQVKIARELCHGVHIMAVKREDLIPKILDLAGIKPLF
>A0A2P8NDV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor sp. StC3|TrEMBL
MSTHRPVQPDENPAGIDLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPYEVYE
RAAIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYTTILQISCRDRNRIAIQGDVLG
AAAMGVCNVLCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDKAKFLSGRKLTAPPA
MFLGAAINPFAPPHDFRAHRLAKKVAAGAQFVQSQYCYDVPMFRDYMQKVGDLGLLDEVF
VLCGVGPLASARTARWMRANVPGVHIPDHIIARLEGAADQKAEGKRLCIDIINEVKEIKG
VSGIHVMAYRQEEFVAEIVHESGVLKSRKPWKREARADDVIVAERLEHLLHDEGGETPQQ
IVKEAAN
>A0A174B5F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus eutactus|TrEMBL
MKIRDLITQDKATLSFEVFPPKKDTDFADVEAAALGIAAFKPDYMSVTYGAGGSTKGHTI
QLAREIQEKYDVPTIAHLTCVCASKEGIKTALADMKNAGIENILALRGDIPKNYDGQVFA
EFSHASELVELIKETGDFCVGGACYPEVHPDSANKHEDIIGLKKKVDAGCDYLTTQMFFD
NNIFFNFMYRIREAGISVPIIPGIMPITRRVQVKNAVKLSGCNVPERFKSIVDAFGDTEA
AMRQAGIAYATDQIIDLMANGVKHIHVYSMNKPEVAAGIQKNLSEILKI
>A0A3N1VSH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia sp. JUb26|TrEMBL
MSFFHANQREALNQSLAEINGQINVSFEFFPPRTAEMENTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATHEELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGVNASV
G
>A0A088F5T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. ML3W|TrEMBL
MKIVDHISNAKGKTLFSFELLPPAKGQGIQSIFKTMDSLMEFKPPFIDVTYHREDYMYKK
HESGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTEGGHAFATDLLKQVDDMNRGQYLHEDIVNSEKTDFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVNKCRENDIHVPIIPGLK
PLTTKKQLITLPKIFHLDIPEVLSEAVSGCKNNADVRQVGEEWLVQQCKELIDFGAPVLH
FYTMSNPGPTRSIVEKLF
>A0A2W5PHE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax paradoxus|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A434I595|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.T.Ca.TU.009.01.3.1|TrEMBL
YIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFEGLDRDPQTHALVASAVAAEQVMD
LVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAAGSAAA
>A0A0R0CJJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas dokdonensis|TrEMBL
MISLSFEFYPPKTDDQRAQLDRTAEKLKVHAPEYVSCTFGAGGSTLSYTSETVRHLGQKH
GFAAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASELIEFI
RAEHGDHFRIEVGAYPETHPQADDALRDLRYFKAKVDAGADAAITQYFYNADAYFHFVDE
VRGLGVDIPIIPGIMPISNFTQLRRFSEACGAEIPRWISKRMQAYGDDAQSVREFGADVV
AGLCRRLLEGGAPALHFYTLNLARPTQNVLSRLTS
>A0A1G7Y7R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium changbaicum|TrEMBL
MNEINREDFFENRFILETLPPRGTNPDKYIAFCKEAVDYGAQVIAVTDLPMGSARVSPIA
PAHMLSELGFNVLMHFSRTTRNAIRIEGDLIAVHMLGIKNLLILSGDDPRVGTYPFSSSI
EDFSIYDVFKLTKLLNEKGEDLAGLKIYGSFSFNPGGVFSPFEKDLNQTLERMELKIQNG
CSFFVSQPIFNADTIIKFLEKSEAEEIFKKTKIYIALMVFESFQQLEHFSKVPGVYVPKE
YFRQKDDSHLEEYSKHQCVSIIEKLAPYVHGFYLTSTTRKMETIKVVSDAVMSQY
>A0A383U1J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Ornithobacterium hominis|TrEMBL
MKVTEHIQNAKEKTLFSFEILPPKKGENVDSVLKNIEPLLQYNPSFIDVTYHREELVYNE
FPDGRITKHSINRRPGTLGTSSIIQHKFGVDTIPHILCGGFSKSDTENMLIDLNFIGIQN
VMALRGDASPHETYFSAHPNGNRFANELVKQIVNLNNGEYIDGHTTSNKTNFQIGVAGYP
EKHMEAPNLQNDMKYLKQKIDTGAEYIVTQMFFDNQAYFDFVEKCRAAEIHVPIIPGLKP
ISTHRHLNIIPHRFHIDLPQNLIDDIENAKTTKEIKAIGIQHCIQQCEELLDFGVPALHF
YSMGKAKNVEEVVKEFF
>A0A395HND9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus homomorphus (strain CBS 101889)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRQQHGDYFCIGVAAYPEGHPADNFQDGQDPVRDVPYL
VEKTQAGADFIMTQLTYDIDAYTKFENMLRNHESGAFKTIPIIPGLMPLHSYKILTRVTK
LSHVKVPPHILSRLEEIKHDDDAVKRAGVDILCDLVDGMRNIPTPGLRGFHFYTLNLEKT
VSFLLERCDLIGPYTEYDEPIEDSAAYLAAPLDTPARALASRRSSISSIPHNRVIVDKIQ
PSDVSSRESVSHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHIPPSVAHKVWGYPVTRDDISALFRRHVSGDLYIVPWSEGGAEEGTG
GLNAETEIIRPELLQLIDKRGWWTLASQPAINGVRSDDSIFGWGPPGEGFVFQKPFVEFF
SPSKDYHTILKPLLERHGHDKLAWFATNVKGDFETSLPGANAEDSDPLDINPANVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDATKNDVWLVCVV
GQEFGAGTEVGSKEEEDETKWMWRELAGC
>A0A140DVW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibaculum rodentium|TrEMBL
MDIYKEQMAQELPRLFDGAMGTLYAQSTGMSSDLVEAANATNPEAIRSIHGRYLEAGAQC
LLTNTFALPLVESEMTLPLVSAAVNNARVAMAEAGCTVPLYASLGPADPGHPERMLSLVD
AFAACGVNRFLFETQAELAPLRPAIDRIRETVPGAQIVVSFAVEADGLTRAGLEVQPLFE
EATPLVDGLGLNCLQGPAGMVKLVESLHWDRPLVVRPNAGSPSVTGHRMTFTAQPDYFAQ
VLAPLYARGISVGGCCGTTPEHIQALSRSLDQADWQQDDLPEPEKDAGFVKRCPDNALMA
LFERESKPIFVEADPPATDDVLPWLAAVKRLKNAGADVITVSDNPVGRPRADSCMLSALA
ASQEDMLMLPHIACRDKNRNAIRSLVTGLSAFGVHQCLVVTGDPVCEEDRSEVRQVYNFN
SRRLAAYIQVLNETVLQTPMCVMGALNVNARNFDIQLRLAKEKIANGVQVLLTQPVLSER
GLENLKRAHEELDCRILAGIFPVVSERNALYLQNEVSGIELDERIPGLYAGLNREESEDL
ALRLSLDVMRAVDAYCDGWYIMMPFRRTQLVARIMGAATDTDMG
>A0A7Y3QA55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 1-2|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSAKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKATTGLVAAPHLTCIDATREELINIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRVAVGA
>A0A7T1TAC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces bathyalis|TrEMBL
MAIGISATRTDSTTTVRDLLATGQRSYSFEFFAPKTEKGERSLWNALRRIEAVSPTFVSV
TYGAGGSSREGTVRNTERIATETTLTPVAHLTAVNHSRAELRNVIGQYADAGIRNVLAIR
GDPPGDPMGEWVRHPEGLTYACELVELVKESGDFCVGVAAFPEMHPRSDDWDTDVRHFVD
KCRAGADYAITQMFFRVEDYLRLRDSVTAAGCETPIIPEIIPVTNVKQIETFAQLSNATI
PDELAERLREVEDDPAAVRSAGIEYATEMCARLMAEDVPGLHFITLNNSTATLEIHQNLG
LHNRP
>A0A7C3GEB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosulfurimonas dismutans|TrEMBL
MEPRSHLHRVLSEGHFAVTAEIGPPKSADGEVVRKKARLIKGYVDAANITDCQTAIVRMS
SIASAVLVMAEGVEPVIQMTCRDRNRIGIQADLLGAAALGVKNLLCITGDHQKFGNHPEA
KGVFDLDSIQLLDMVRRMRDEGKFMCGEDLTGARPEFFLGAAANPFADPFEFRVKRLAKK
IAAGAEFIQTQIVYNVERFRKFMEMARDMGLTEKAYILAGITPPKSFGMARYMKYFVPGL
DVPDEILKRMKEAKDKREEGINLAVEIIQQVREIPGVAGVHIMAIEWEEAVPEIVKRAGL
HPRPLEAEVRPAVVVEVEKPVERVEVVAPPAEEVPEEAPPRVEIPVEAVKEVFSTVRSSI
ESLREGVNLLHDSLARLERALLGGEVVPAEAPEVPRVEVKVEERPPVEEKPVEAKEVPEE
KEVAEEKKVEEKRVEEEKPAEEVEARVEEKPAEEEKPEEKPAVEVREEKPVEKPPVEEKP
APPAEGVEIGSFSGEYRPLSERAAGLPEDLYKEPGTAFIREVEIGKGEKAFKVGGTNVLP
FHLFEGEMRHEPRVAMEILDVKPENWPESLARYFADVLDDPAAWARKCVETYGAEALCIY
LMGTDPNYLNLDAKHAREVVEKVAGAVDVPLIVWGSGHAEKDVEVLREVAEVVGDRGAVI
GPVEEANHRTLGATAMGYGLPVVASSPIDVNLAKQLNILLENVGVALDKILMDPSIGALG
YGLEYTYSVMERIRLAALYAQDDKLQVPFICNVGREVWKAKEAGLPSDETMGDQEVRGVL
MEAITSVALALAGGDLFIMRHPKAIELTKLIIKELMQQN
>A0A7U4TLN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium UKL13-1|TrEMBL
MSQPTISFEFFPPKSEAMEAKLWDAVSRLAPLSPDFVSVTYGAGGSTRERTHRTVKRILD
ETSLQPAAHLTCVAASKAEVDEVLREYWAAGVRHIVALRGDPPTGVGTAFEPHPDGYVNA
TEVTAAARRIADFDVSVSFYPEKHPESPSLQHDIDVLKAKIDSGATRAISQFFCEADVYL
RFRDAAAKAGITIPLLPGIMPVGNVAGYTRMATSTGTSIPAWFAEAFDGLDQSPEVRDMV
AASVAADLCLKLQAEGVDRFHFYTLNRAELSLATCRRLGLKTPVTEKDAA
>A0A510HMP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus thermophilus|TrEMBL
MKIRDLLKARRGPLFSFEFFPPKDPEGEEALFRTLEELKAFRPAFVSITYGAMGSTRERS
VAWAQRIQSLGLNPLAHLTVAGQSRKEVAEVLHRFVESGVENLLALRGDPPRGERVFRPH
PEGFRYAAELVALIRERYGDRVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIGIPILPGIMPVTSYRQLRRFTEVCGASIPGPLLAKLERHQ
DDTKAVLEIGVEHAVRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGLRPASGQP
>A0A1X1I0K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2V5V589|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIIRGDFPTFSFEFFPPKTPAAAEILYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCICHNEEEVEAILLRYARSAIGNILALGGDRPRDVPYDKSR
DSFQHAVDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHFKAKVDAGA
DYIVTQLFFDNRDFFDFRERCALAGIHIPIIAGIMPVTS
>A0A0R1RI94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Furfurilactobacillus rossiae DSM 15814|TrEMBL
MVADAEHQKLTDDGQRLTHTDEAQTEHHFLHPSVGHKSILVEMDPPTTFKTASFYRGAER
LRDAGVDAITLADNSLAAVRVSNVAVAAKLKLEYGIHPIVHLTTRDHNLIGIQSEIMGLH
SLEIDDILAIAGDPAREGDFPGATSVRDVNALGLIKLIKQYNTGVSPSGKDLDDRPNFCV
AAAFSPKITNGVLATRGIKRKIDCGADYLITQPVFDIARVNELADAFSQCGLQIPVFVGV
QPLMSKRNAEFLNEHVSGMSLPQSILDRMAQAEIDGNEHEVGLQIAEEIADAICDRFGGV
HVVTPFNRYKIAAKLVTHIRQRENVVVSR
>A0A3E1E2X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHISDILRQHRPALSFEFFPPKTAEASEALYATISELEPYKPSFVSVTYGAGGTTRDLTH
DLVVRIKDTTSLRPIPHLTCVCHQESDIQSILERYAAAGVGNILALGGDPPRNLAGYDRA
KDAFQHAADLVAFIRRFNERGFHPDRRGFGIGVAGFPEGHPSTPNRLLEMDYLKAKVDAG
ADYICTQLFFDNHDFLDFRERCELAGIRVPIIAGLMPINSAKGMARMAELAAGARFPAKL
LKAIARANGDEEAVERIGISYATEQCRDLLDHNVAGIHFYTLNKSGATRQIYANLGIRDT
EALAAR
>A0A6C0QRS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus larvae subsp. larvae|TrEMBL
MRPDLRLALQHQLLTGDGAMGTYLYQLGFPVGISYEELNLLQPQVIADIHRRYYEAGAKI
IETNTFSANKEKLSKFGLEQEVKRINRAGADLARQTVGDDAYVMGAVGSIRGSKRKNVLE
ADVRIAFHEQVEALLEASVDGLLLETFYDLDELLIALRLIRNLSDLPVICQFTTEGNHTT
HDGIPLQEAFERLKDEGADVVGFNCVSGPNGIMQSIGRIHPLEQVPFSVYPNAGIPDYVD
GRIVFGATPEYFAETALRFADLGARIIGGCCGTTPEHIAAISKALRGYVPSAEQAFRLRG
TETGRDEEHPVISTGTAETGDSSYMDGVQNLVDLVKQRPTVIVELDPPRTLDINKFMVGA
KALKDARVDAITMADNSLAVTRMSNLALGALVQQRLNVRPLVHIACRDRNSIGTQSHLMG
MDALGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNKGLAFSGKPLKKKARF
VIGAAFNPNVKYLEKAVQRLEKKIAAGADYIMTQPVYDHALIERIHESTKHMDVPIFLGI
MPLASGRNAEYLHNEVPGIQLPDETRGRMAGLEGEAGRAAGTEMAKELIDTALQYFNGIY
LMTPFLFYDMSVALTEYIWGKTSSRHPLLSRV
>A0A7W5U9N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK612|TrEMBL
MSHIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLTEKCFILVGV
GPLASARTARWMRSNVPGVHIPDEIIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREAGRTDALVAERLHQISEGREENQQAMAEIAA
HHTPPQTH
>A0A841YHH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria fleischmannii|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRAFEELSLTHPEDVLNIHKAYIEAGADIIQTN
TYGANYIKLKRYGLEDEIKRINQAAIRLAKRATSGTGTYIFGTMGGINGASDSKVEQAPL
DEIKRSFREQLYCFLLEGVDAILLETFYDPNELKTVLQIVRENTDLPVIANVSMHEPGLL
QNGEKLPDVLQEIADLGADVVGVNCRLGPYHMARALETVPLLDNAYLAAYPNASLPEMQE
GKIIYQAETDYFQEYGEIFRKQGARIIGGCCGTTPEHIRAFRAGLRSTKPIKTKEVRPII
ELVPEEPSPLEGVRLLDKVREECTVLVELDPPRTFDTEQFFEGAKALHAAGADAITISDN
SLATPRISNMAIASILKHEYDIKPLIHLTTRDHNLVGMHSHIMGFHKLGLHDVLAVTGDP
TKVGDFPGASSVFDLRSVELIQLIKKFNDGISYTGKSLKEKARFHVAAAFNPNVLNVEKA
VRLIERKVEYGADYIITQPIYDTQKARVLNEALKEAQISVPVFVGVMPLLSSRNAEFLHN
EVPGIRLTNEVRERMREAEKAGRGNEEGMLISKEIIDSISEHFNGVYIITPFLRYDLSLE
LLQYAKSKEQVHVI
>A0A5E4INQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon|TrEMBL
MSKLREKLQSSKFILTSEISPPRSASLEKFRAEARQCTADAINVTDYSGALQTMSGLGAS
IALMQEKKEPIYQVTVRDRNTLGLQGDLIAAGAFGIENILALTGDSPRIGDQKQAKPVYE
ITSVDLVKLCLLLNKGETLGGVKLKVPTKFCVGSALTPGHRDLKNEVSKMQKKIDAGTQF
FQSQPLFSRGEIERFVSEYEKHSGESAKKMLKLSIIGVLPLHDLSVMPILKSLPCLFIPK
ELEERMSVAQKKGKLREEAKAHAIELVDAIKEIGFAGAHVLPMGDVRLFEEIKKEV
>A0A7Y0R615|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridioides difficile|TrEMBL
MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAANVTDFQSAVMRATSLA
TCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLLALTGDHTSVGDHPQAKGV
FDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTPEYSPIEVQLLKMQKKIKAGA
KFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSPGMAKFMTANVPGIFVPDEQIER
LRAVGKENWASEGIKMAGELIKQLKEEDLCDGVHIMAIGAEENIPAILDAAGL
>A0A822L6X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa PCC 9432|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGSLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPVHN
>A0A7Y0N542|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridioides difficile|TrEMBL
MNINEYIKDSILVFDGAMGTYYSKLKNNAFNCEMANINDASTILSIHREYIRAGCKAIKT
NTFAANEILLECDFKTVKDIIKSGYEIALEATKNTDVFVFADIGPIPTLNDRDLLSDYKK
IVDIFLEIGATNFIFETFSSDEYIPEISDYIKKKQPNSFILTEFAVNPEGFTRLGKSGKK
IFESISKNKNIDALGFNCISGPHHLLHFIKTIDINDSIVSIMPNAGYPTIINNRTFFEDN
SDYFSEQMLEILNQGVRILGGCCGTTPEFIKKTVDTINSSYKCESTIEKVISSKEKIKPI
SKNKLVEKLKVGKKIIAVELDPPIDTDIEFFMNSAKKLKDYGVDAITIADCPIARARVDS
SLLACKIKRELDIIPIPHMTCRDRNINATKALLLGLSIENIDNVLVVTGDPIPSAERDEI
KAMFSFNSSILANYIKTLNENTFNTPFNIFGALNINAINFDSQLKHAKIKIENGVTMFLT
QPVLTEQALINLKKAKKILPAKILGGIIPVVSYRNACFMNNEISGITVSQNIIDMYKDIS
KEDSTKLAINISTQIAKEIEPYVDGYYIITPFKRIDIVCDIIANINK
>A0A495S916|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium defluvii|TrEMBL
MKITEHIKKANGKTLFSLEVVPPQKGIGIEDLYRNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTPGGHASAMDLVHQINNLGRGKYLHDDDQICDEHNKFCIGVAG
YPEKHIEAPSMNYDLKWLKEKVDAGADYIVTQMFFDNKRFIEFVQKAREMGITIPIIPGI
KPIATKKHLKLLPQVFKIDLPEELINEVEKAKNNEAVKEIGIEWAITQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>E3CAT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limosilactobacillus oris PB013-T2-3|TrEMBL
MTSLSYEVFPPNSTVGINHLNQVLAALQDLAPSFISVTCSSQTARLAQETVKVADYVENC
CHVPAMAHLPAWYLSRPDVDRIMAQLRERHVGRVLVLRGDERPGLAKKNDFPHASDLIDY
IRQNYPDFQITGACYPEKHPESLDMVAELQHLKLKVEAGCDQIITQLFLDNRCYYRFREL
CAIAGIDVPIIAGIMPIINERQANRILRTSAVAVPEKFKDILAKYHDHPEALKQAGISYA
IDQIVDLATNDVSGIHLYTMNQADTARQVEQNIGALLQVSC
>A0A1T4MMD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter intestinalis|TrEMBL
MQKFAFTHRFNKKSCYIIRMSFRKPKNIALELVPRTLDGVLAEARESLSSFPFVTSINIP
EIRRLPIKSFEPSKRLLESGLVTTPHFRLIDRSEKDLLQKIAVLVEAGLSQVLLIGGDPP
KESPDFVPSGLTTLQAIQAVKREFPQLKIYTGLDPYRSSFREELDYARAKRDAGSDGFFT
QPFFSVGMLELWLEQLPDAEIWFGIAPVYTERSQNYWERVNKVVFPPNFSFDRDFNTRLA
RQLLVTISETQQRAYLMPVANGALAYLRDIFEA
>A0A2G3CGG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum chinense|TrEMBL
MLILASILQVDAGADLIINQLFYDTDIFLKFANDCRQIEINFPIALGIMPINNYKGFLRI
TGFCKTKAIENALRRSRVRELLRSIESLGYYSKAAYCKAVEISFAAKIPMQAIANALYSQ
ESENSQEALRVLDIILRLYAAKQFRCSNPGSIVILQTRCSISSVVALAQAITANIQANPA
PAPQQQGGDSTAARICDFMRINPPEFYGCKSDEDPRLF
>A0A7C5GU19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichales bacterium|TrEMBL
MARWGFDGRSLSFEFFPPKTDTGREKLRRTHARLAQLRPEFFSVTFGAGGSTREGTYETV
REIQASGDAPAAPHISCIGASRESIRELLQAYRAIGVRRIVALRGDLPSGMVERGEFAHA
DELVAFIREETGDWFYIEVAAYPEFHPEAPSASADLRNFARKVAAGANRAITQYFFNPDA
YFRFVDWCQAFGIGIDVVPGIMPIVNYRQLARFSEGCGAEIPRWLRWRLEELVDDVEALR
AFGTDVVSAMCERLLAGGAPGLHFYTLNMAAPTLAICDRLGIDVQTPA
>A0A1I1LGS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kushneria avicenniae|TrEMBL
MLREALREQRFICVVEFVPGLSGERGAVFESMMQRAQLGHWPMVAAVADRVSSSQDLSPL
AAYSRLTHSLPTLLHFSGKDRGRHDLLRQLEQMDAAGLDQLLLLSGDRLPGHEPGQPVRY
LESVPALQIVRQARPSWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGFDAQ
KHREARQWMQRRAVPVPLLACVMPLTFKTATLLEQVPGVVISPSMRDLLAAEEAVSRAHA
RERSLFRLGLQIIGLRLMGYAGIHLSGIHTPAQLQALEQMIHAQQEGIQTLAQWSAAWEP
SWQVSGLPTVTFHPAYADWHMGESGVRATVREQYRYHVLSAVHTLLFSRRNPISRGFGWL
CRRPVWRIPRGARWLHQLERCLKGPAVGCYTCGSCRLEDTLYVCPETCPKGLANGPCGGT
RLNRCEFGDRECIHSVKYRTATTTGQTHVLTERLIPCVEADTRHQSSWPRWFTPAVEGKH
HGRRVPDDAIKKTK
>A0A8J8BJA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Silanimonas sp|TrEMBL
MTVSFEFFPPKTDEQRQQLDRTVDKLKVFAPRFVSVTFGAGGSTLSYTPETIRHLREQHG
LDAAPHISCVGGTRAEIVELLQRYRAMGCTRLIALRGDLPSGMGALGELRYAEDLVRLIR
SEFGDAFRIEVGAYPEVHPQADDARADLRHFAAKMAAGADSAITQYFYNADAYFRFVDAA
RAAGVTQPILPGIMPVSNFTQLRRFSEGCGAEIPRWLGKQLAAFGDDAEGLRAYAADVVA
ELCRRLLAGGAPELHFYTLNLARPTLAVLERLR
>A0A346XYH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euzebya pacifica|TrEMBL
MTHRTVQDAGPTATATPNRPLLDRLHSGTPLLGDGATGTMLHLRADLPSDACFEALVLTA
PDVVLGLHRDYVAAGVDVLSTNTFAANAVQLRRHGHADDVEAINRAAVDLARTAIGDADV
LLAGTVGPLGVPMAPYGRMSAEEAKGFFVQQMRALEGVDVIALETFGDHGELLTALAAAR
EVHPDVPVIAHATFARDDRTVLGVLPGRVAAELHAAGADVIGVNCSGGPAQIQRLIEAMR
RSVPDARLSAYPNAGFAEQVGGRVLYPATPQYFAQATERLRAVGVQLVGGCCGTTPEHIA
AMRTVLDDPTPPAPIAIAAPTAAPTSDAPTLEPTELGYRLAQRQFTVTVELSPPRGHDTA
RLLRAAELLRDAGAHLIDVADSPAARMRMSPWAAAQVLQSQVGLETILHFPTRGRNLLRV
QGDLLAAHALGLRNLFVTMGDPTRIGDFPEAMDAFDIAPSALIGTIAGRMNVGEDLGGND
IGRPTGFTVGCALNMFADDLDHELDVLERKMEAGAHFALGQAVFEPSRISRFLEAYEARH
GRPFDLPVLMGIMPLFGTRQARFLHEEVPGIVIPKAIFERLDAAGDRAPDEGVAIAEELV
EAVRPLVAGAYVIPALGKYELAARVVASATR
>A0A3A0CLU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MQKTLREKLFQTKDFLFGIELLSIRGSMTEKSAVKARDFANDLVACPAVDWISITDNAGG
NPKLAPHALGKPILYAGKEVVIHMTCKDLNRNGLESEAWVLSSEGFHNILAMTGDYPVAG
GGGMAKPVFDLDSIGLIAMLNKMNHGFEYRKNGARNDTERLGQTQFLIGAVTSNFKMREG
EVVPQYLKLQKKIECGAQFIINQVGFDSRKIHELRIYMDQHAMKHVPLIGNVYVLNPRVA
QIFHDRKIPGIVVTPPLLELCLKQRQSADEGRAFFYEFAAKQIAIYRGLGYRGAYLGGVY
DFAAVERILEIERSFSRDDWKQFAREIRYSRPGEFFYYSENSETGLADSSVRSPASEMKK
SNHVGLVYHLSKMTHELMFTPDRTLAKWGRRLCQHAHDLSEGPGLMRLAERWSKMILFDC
RDCGDCSLPEIAYLCPESQCAKNQRNGPCGGTKDGLCEVDGFGDCIWLRAYERLKHDAKE
LELLRHVPVLQDQALRGTSSWANNWLGRDHAAKAVGQICTSEVKKRNAEEHELQLTP
>A0A7X9I7L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelolinea sp|TrEMBL
MKRDTFLKRLHEGKPLVADGAMGTLLHDRGVNFDSCFDELNLTNPALVGSIHQEYIKAGA
EVILTNTFGANRYKLERCGLEELIDEINQTGVELARRIVRASYKNVLIAGDIGPLGVRLA
PFGRVQVEQAREAFKEQIQALVGAGCDLLVIETITDLYEIREAISAAQEVDPDIPIVASM
TFTRDDRTLLGDDPQKVASKIFSFGADVIGINCSGGPNQLLRLLKKMKREIPDGLFWVKP
NAGWPEQISGRIFYPASAEYFGEYALAFWQAGARVIGGCCGTTPAHIQSIRQAIDSHETE
AITGGTTLEMVEEESSEAETSEPSKFAQKLNNGKFVFSVEMQPPRGLATKKIIAGASMLV
DSGADAINVADSPMARMRMSPWAVCSLLQHKVSVETILHFPTRGRNLLRVQGDLLAAHAL
GVRNVFVIMGDPTAIGDYPEAMDNFDLAPSGLVKLIKQRFNQGVDQSGSDIGQPTNFFVG
CALNLAAPDPQREMDILRRKIHNGADFIITQPIYDASLISNFLHGYQATGEELKVPLLIG
ILPLVSARHSAFLNQEVPGISIPEHIHQRMQTAEDQGIGPQEGIRIAIELIKEVREVAQG
IYITPPFNRFDYVAEIIDQSK
>A0A7J7LUZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingdonia uniflora|TrEMBL
MKVVEKIREVSEKGGIVYSFEFVPPRAKKGDIDGFEQGVKDVLETIDRMVEHGPSFCDIT
WRAGGTNAERVLRIAKEMQNTIGVETMVHLTCMNMPLDEIDHALDTMKANGIQNVLALKG
DPPVGKDQSQTVENGFSCALDLVNYIKARYGDYFGITVAGYPEAHPDKIQSNGLADLDDY
KSDLVYLKRKVDAGADVIISQLFFDTDIFLKFIKDCREEGITCPIVPGILPITTYRGYLR
MIGICKTWVPAEVTAALEPIKGDDESIRNYGIELATKMCKKLLAYGIKTLHFYTLNQDKS
TLAILQVTTLPISGL
>A0A7V8AKG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MKEDDPDNDRMRRPSLVLPVATTLPGTVSISFEFFPPRNERMIETLWECIRRLEPLAPRF
VSVTYGAGGSTRERTHDTVARIARETSLRPAAHLTCVGASRAEVTAIARRYWEGGIRHIV
ALRGDPPEGQNRYVPHPEGYAYAADLVDGLKRIADFEITVAAYPEVHPEAPSAGFDLDNL
KRKIDAGASRAITQYFFDVNVYRRFMDRVRATGITVPVIPGILPVTNVVTMLKFSQACGA
SVPAWVRALFDGLDADPDTRRLAAAVFAAEQCRALAAEGVTDFHFYTLNRADLVFAICHI
LGVRQR
>A0A6N7M9J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaeta sp|TrEMBL
MGRFRDAILDSDEFVITFELVPGRGFTGRGIENIHKSAEEIKNFDAIHAISLTENAGGNP
ALLADVLGQEIVAAGVDIIVHFSCKDMNRNFIESRAFALQRQGVSSLLVITGDYPISGFL
GLPKPAFDLDSVTTLHFLKKINEGLEIQVGRKTQVLEPTSFLLGAVASPFKWTEASSVMQ
YFTSWKRKSGLVRTI
>A0A3D4QG94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MPKPPTDTLRQVAAFGRAAVAGGQVAAALPDDVEVSFEFFPPSSEGAEANLWNSIQRLAP
LNPKYVSVTYGAGGSTRERTHATVKRLLGETDLLPAAHLTCVDATTQEIDTVAQDYWDMG
VRHIVALRGDPQDASGHYTPHAGGYAFACDLVAGLRQIGDFNISVGAYPEVHPEARSAKA
DMDNLKRKIDAGADQAITQYFFDTDVYLRFVDQARAAGIWVPIIPGIMPIHNFTKVANFS
KRCGATIPRWLGDLFDGLENDPDTHKLVAASLVAEQCRTLHAFGDKQFHFYTLNQADLTY
AICHMLGVRPKHPVGSDAGDQANKKQAG
>A0A8C5B2F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gadus morhua|TrEMBL
MQNLQRPNKFYFGGVLPQCNVISNSGESSKESSRCSTPLLDADRSDRLREKMRKRMESGD
PWFSLEFFPPRTASGAVNLISRHVSILPSPLYLRSMLKCASAHRFDRMGSGGPLFIDITW
HPAGDPGSNKETSSMMIASTAVNYCGLESVLHLTCSNQSQETITGYLTKAKQLGLKNIMA
LRGDPLGTDWEDEEEGFNYATDLVKHIRSEFDDYFDICVAGYPTGHPEAQSYAEDLQHLK
EKVDAGADFIITQLFFRADTFLKFLRDCRAIGITVPILPGVFPIQGYQSLRQLVKLSKLE
VPEEIMEVIEPIKDNDAAIRSYGIHQAVEMCRVLLDSGAVPGLHFYTLNREVATTEVLRQ
LGLWIEDPRRPLPWATSANPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSP
AFGELNDYYLFYLKSKSSKDALLKMWGEELTSETSVFEVFTSYITAQVNRGGHKVMCLPW
NDDALATETNLLKDELEKVNRRGVLTINSQPNINGKPSSDPIAGWGPAGGYVFQKAYLEF
FTSSENVTALLKVLKKYEPRVNYHIVNVQGHNMTNAQDMQPNAVTWGIFPGREIVQPTVV
DPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQV
LDDMFELLDAPPEVVGDGALAPVALGDGALAPVGLGDGALAPVALGDGALAPVGLGDGAL
EPVVGDGAPQPLSASQ
>A0A374NJC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum hallii|TrEMBL
MAKETAQEVYQEEYPIFAAADIGPILEERDSEEADILQQYYEICDSFLEAGADIFVLETF
PDTQYVLKMAEYIRKSCPEAFIIGQFSLTPTGYSRTGFHYKTILQEATQSGLLDGAGLNC
GVGAAHMKKFLKSYIEEFGVPEDMVLTSLPNCGYPQIVRGHAVYSDSVPYFGEKLGEISE
LGVQVLGGCCGTTPEYIGEIYKTVFQAKKTEGAVKIPTKIVWGDVTKRVQKRKEAAVHIT
QAGEQKEAIKEKQVTNTFRQKLEMGELVCAVELDPPFDTDDTKLLNGAKALLSTKADIIT
IADSPLARSRADASLMAAKIKMTTGMDVMPHLSCRDKNRIAIRSGLLGSYASGIRNYLFV
TGDPVAREDREFTKSVFDFNSIRLMKFAQSMNQEVFKDDTIFYGGALNQNGAGPENIAGR
MLKKMEAGCRYFLTQPVYDKEGIERLTFLKERTGAKILIGIMPLVSRRNALFIKNEMPGI
HVPDEVVAKYKEGASREEFEEAAIEISKQIIEMGKGIGAGFYFMTPFNRVSLVKSILEYV
>A0A7X4IPS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MADNRGRRQGRPGRRRRISGMAEKTMNGPVSANGLKSGGNLERVLAAGGFAVTCETSPTA
TTDLAPLLERVAPLKGVADAVNVTDGATAKAHVSSLVLAGAMMRQGIQPVLQFTVRDRNL
IALQGDILGAGALGIPNILCLTGDDPKKG
>A0A6B2H589|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter fetidus|TrEMBL
MKVTDHFKNANGKTLFTFEILPPLKGENMRTLFNHIDPLMEFNPPFIDVTYHREEYVYKQ
RENGLLEKITTRKRPGTVGICAAIQNNYKVDTVPHLICGGFNKEETENALIDLHFLGIDN
VLVLRGDCVKSEQRFVPEPGGHHYATELIGQVVNMNCGRYLDEEQVYNSGTDFCIGVAGY
PEKHFEAPNQKSDLRWLKKKVELGAEYIVTQMFFDNQKYFDFVNRCREEGINVPIIPGLK
PMTTKSQLTLLPSLFHIEVPCELADAIEDCADNKAAAQVGIEWAIKQSRELMEFGVPCLH
YYSMGKSESVRKVAEALF
>A0A3C1BQA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MTGISFEFFPPKSPEAEEKLWRSVGRLEPLAPDF
>A0A0Q5E9M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. Leaf125|TrEMBL
MPTASQHRASRDSYRPIRVSIEFFPPKTDEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMIKETSLQPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPQDGVG
TAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEAPTLDADIDALKAKVDAGADQ
AITQFFFENDIYLRYVDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLDNDVDTRRLVAAAVAAEQVLDLVDHGVNDFHFYSMNRSDLVYAICHVLGLRAQAPKV
AAKAA
>A0A2E7F8A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MPVESSLVRRLLAGEFALTAEVTPPVSAGPAELLEKSAPLRGLVDAVNVTDGAGARVHMS
SLAAASILNANGIEPVVQLTCRDRNRIALMGDLLGIGALGIYNLLVLTGDNPKAGDQPDA
KPVFDLQSAELLAIAHEMTANGFIQSKTAKLTNEGVQPNTKTISTPPKFFIGAADTPIAE
IEEKWLAGLRKKQACGTRFIQTQLNYDMDIVRQYSKILVDQGFTEHMFFLIGNGPLPSAK
SAIWMRDNLWGVVVPDDIIHRLDQAKDPKEEGIQICAQQMQEMAEMPGVAGVHLMAPVNV
PAIPVAIERANLAR
>A0A367FF86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerisporangium album|TrEMBL
MALGRSSMRPDRVPTVRELLASGGRSFSFEFFPPKTDEGERLLWRAIRELEALRPTFVSV
TYGAGGSSRDRTIEIVERLAHETTLTPVAHFTAVNHSLRELRHLVGRFADAGVRNILAVR
GDPPGSDPLAEWIKHPEGVEFAEDLVRLIRQAGEFCVGVAAFPYRHPRSPSIDSDTEYFV
QKCRAGADYAITQMFFRAEDYLRLRDRVAARGCDTPIIPGIMPVTQMSTIARSEKLSGAP
FPPEVAERFEAVADDPEAVRRLGIEHAAELCQTLLDEGAPGIHFITFNKSSATREVYQAL
VPAAAGVKA
>A0A2E9J4B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichales bacterium|TrEMBL
MXLKVSFEXFPPQTDLMEEXLKTNVQKLIGLXPSFVSITYGAGGSTREKTHSVIKKIXTQ
TPLNVAAHLTCXDASKNETKKVIXDYLDIGVRHIVALRGDXKDLNAFEPHPEGFRNSIEL
IEYIKSRANITVSISGYPEPHXESXGYQXDIDFLXAKIDSGADQXITQFCLNTDYYLRYR
DQLDKEGXTXPIIPGIMLIKKFRGIEKMSKKIGVEVPXXILNIIEKNLTADEEKNAAEEF
AXDQCEKLXKNGFENLHFYTLNESEIMXAIANKLGXENHAN
>A0A3C0VNS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MTSISFEFFPPKSAEAEVKLWDVINELAAIKPDFVSITYGAGGSTRDRTHQCVKHLVTKT
DLKPAAHLTCVAASKSEVDEVIEDYASAGVKHIVALRGDMPDMEAFSPHPDGYNGSVELV
DALAQRGGFDITVSAYPEKHPESGDMQTDIDLLKAKIDAGATRAITQFVFDTEQHYRFRD
VLADNQINIPVIPGIMPTTNFKGVLRMSEACGASVPIWMKSKFDGLDDDLESRRALAIKL
ATNQCRDLINSGFENLHFYTLNQVTVTKAVCKTLSLEKVGV
>A0A3D4F256|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MTDISFEFFPPKSPEAEEKLWTAVGRLEPLAPDFVSVTYGAGGSTRDRTHACVRRLVDET
QLKPAAHLTCVAASRADIDSVIEAYATAGVGHIVALRGDMPDMGEFQPHEDGYSGSVELV
EAIAARGGFDITVSAYPEKHPESSSLQTDIDLLKAKADAGATRAITQFVFDTPAHLRFRD
AVAAAGITIPLIPGIMPTTNFAGARRMAAACGTHVPDWMSAMYAGLEEDPDTRKHIAASI
ATDQCRTLLNEGFEHLHFYTLNQADLTFAVCRILGLCDSQQESKPL
>A0A1F4C0M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_65_24|TrEMBL
MSPAPLAVMPLRPENEGLLRESIMRLVGGASIEASVKNLAEVDTYPAFLPPASTVFLPWL
PGLPYTHLVSVAARLRQAGFEPVPHIAARRLPDRASADDLVSRLCGEAGVTQVLVIGGDV
DRPAGPFDSAAALLQAGLLQQRGMRRIGVAGYPEGHPRIPDDRLDGVLNQKMQWATQAGL
ELYVVSQFCFDGVAIERWLQRLHGAGVTLPVHVGLAGPASMRTLINYGMRCGIGASLRAL
RSHGVSLTRLAAQSGPESVVWHLAEAQERGALPLPLKLHFFSFGGVEKTARWMRAVSAGR
VRLSGRQFELTA
>A0A2S6G511|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter persicus|TrEMBL
MESQKQFKRRFSFEFFPPKTDKGREKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LSLHRQGISTAPHLSCVGGTRQEIGELLDLYKENGINRIVALRGDMPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARSAEDDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSESIRQ
FGEEVVTRMCEKLLAAGAPGLHFYTLNQAQPSLSIWENLGISDREKIAF
>A0A2E2E7X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSETITMTEVDQIVNFMSTCTLEVTPGGAAKIDDFRAVLRPDQIVYVTFLPGSDFRDTVV
TVKKLKDQGMRPVPHFAARSIPTKAFFEENLKMLTAETGVEEALLIGGGVDNPVGEFSES
MEILRLGLFEKYGIKHLGIAGHPEGSPDIKPAEVIRALLDKNAYAAQSPIDFYIATQFCF
EAEPLIQWDRQIRAEGNTLPIHIGIPGLATIKTLMKHAQACGIGNSMRFIAKQARNIAKL
MSVSEPDKLVRDLAHYKATDPNCGIIQAHLYPLGGLKKSSAWLYAIQDGKIELSKKGGFK
TDYAVE
>A0A2D6RG27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colwelliaceae bacterium|TrEMBL
MNSGSELKARYNDNNRGVYFIGTTPPKSDTPIEQVDTIAQKLLERVSDIDVDGFIVYDIQ
DEGSRTNDPRPFPFKCTHDPRLYSSLLNKKSTRPVITYKSVGQSSVEEFHQWADEAWHDY
NVRDLVLVGSPSHKNQVSLSLNEAYSALQDNENNFFTGGITIAERHATKGNEHQRLIEKY
EQGCNFFISQAIYNPQATIDQLTRYAIECKNSGLKPQRIILTFSPCGSQKTLEFIEWLGV
SVPEATSLRILNAEKPLYESIRICANSLQQILDAVIPYNLPLGLNIESLTNRKEEIDGSI
LLYKLLRSMMDNYLAKNELMALSQA
>A0A228I182|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. AU16741|TrEMBL
MKSIELSFEFFPPKSADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDNLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DTRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNLATATRTICERLAV
>B9DHL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabidopsis thaliana|TrEMBL
VTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTKIPAELTAALE
PIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMNLGLIDESKISR
SLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQF
ARPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPETKIINEQLGK
INSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP
SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRS
WANLYPEDDPSRKLLEEVKNSYYLVSLVDNNYINGDIFSVFA
>A0A8C2C9W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRLELNSAGLCPPGALLVFCSLCVRFDRMGSGGPLFIDVTWH
PAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMAL
RGDPIGEDWVEEDGGFNYATDLVKHIRCECDDYFDICVAGYPTGHPEAESYDEDLRHLKE
KVDAGAHFIVTQLFFRAETFLKFVKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEV
PEEIMQVIEPIKDNDAAIRSYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQL
GLWAEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPA
FGELTDYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWN
DDPLAPETNLLKDELEKVNCRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFF
TSSENVTALLQVLKKYEPRVNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVD
PVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVI
EDMFTLLDSPPETQEEGSQS
>A0A8C1BH14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
TRLFISDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRWFSLEFFPPR
TAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHL
TCCNQTKEKITAHLNKAKRLGLKNIMALRGGMNTLAADRQNLTGLLQLMAKGMSEPIKDN
DAAIRNYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWA
VSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKS
KSPKEALLQMWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDE
LEKVNRRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLK
KYEPRVNYHIVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFAL
WIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQ
ED
>A0A7X9B549|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MAQQNRQLDMSFDGDQRLAEAFRQGHFVTLLEVATPTANQPIDSAAAVLQPLLKQISTLD
EITGITLNDCLPDEQRHDPVEFAQLLLRDFGKTVVLTLSGKCSNLDRAKAICAAAYGRGL
RNVLAVTGDLPNQAEDKAPTPPTPRPYLDSVEALRSLSSFNRQLCLGAVVNPYKYTAEDQ
CLQYAKMLRKLRSGADFLVAQAGWDMKKSQELQWFMQMRELHEPIIARMVMFTREEAQRL
GECRQPGIVLPVPLAAQIMREAAMQPSDYIAAQIHRCALQIIGYRVLGYSGVQITGCRNP
KTIAQLLSHCKELTATCDDYPSWLKQWQELHGAISFAPAPTERHTGTPHYLFRQLLNPQH
RDYVPQDRFHGQFLEKPGMADRWRFFMAKWGRRDNGCFGLPYTTACPKQLRFGPCGGSQC
DGFCEAGHQPCFFQRVLRLLADRNAIQLLEEGLPEHD
>A0A5D4RQX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rossellomorea marisflavi|TrEMBL
MRALLDALSENILIADGAVGTLLYSYGVDRCFEELNLSHPEEIINVHKQYIDAGADIIQT
NTYGANYAKLSRYGLQDQVKEINEAAVRLAKKAAGQGTYILGTIGGIRAINQHISIEEVK
RGFREQLYCLLLEGVDGILLETYYDFEELKTVLQIVKKETNLPVIAQVSMHETGVLQNGM
DIKDALGELELLGADIVGINCRMGPFHMVKSLEGVPLPKSSFLSVYPNASLPNYEEGRFY
YAAEPDYFGDISNELRLQGARIIGGCCGTTPAHIKAVKERLISREPIKEKKVKTQELIKL
KDPHIQKNLLHRKVKEKKTLIVELDPPKHLDTGLFFQGAKALKEEGIDAITLADNPLASP
RVSNDAMGTLVQQKFGLDPLVHITCRDRNLIGLQSHLMGLHTLGIHNILAITGDPAKIGD
FPGAASVYDLSSIELIELIKQNNDGLSFSGKSLRQRTNFSVGAAFNPNFRHLDASAKRLE
KKQHAGADYFISQPVFSCEHLVQIAEATSHLQAPLFIGIMPLISSRNAEFLHHEVPGIKV
PDEARKLMKEAEGDPLQSRAVGMEIAKELVETAMELFNGLYIITPFMRYDMSIELIRHAN
LIEKEKREVPYDHNIV
>A0A223MTQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium innocuum|TrEMBL
MIENYLNTQGYMLFDGAFGTYYAQRYAEDQKPCEMANLNHPKRVAAIHQEYIEAGADAIK
TNTFSANEQHLECSWEMIRRILQEGYRIAKEAAKDKVKVFADIGPIMEQKNVSLAQQYQR
IADVFLAEGADCFLFETLLNTQELHAVTSYIKEQCPQACIIVSFAVTADGYSRQGIAMSR
LLQDCLADEHVDACGLNCVCGPMHMKRLLDSIDRTQKPILIMPNAGYPTILANRTYFRDS
STYFAKEMREIWQKGARLLGGCCGTTPIYIQKTREALQEHKIIQKVQQPAQETERIPQED
HNPLRRKLQKKQPVIAVEFDPPANCEIERFMNHVEFLKEAGVDAVTIADCPIARARVDSS
LIACKLHRELGLDVIPHMTCRDRNINATKALLFGLQIEGIRNVLVVTGDPIPSEDRQEVK
GVFNFNSQILAGYIRDLNETMFTSPFMVFGALNLNAVNFEAELAKAKRKVTQGMEGFLTQ
PVHSRQALFNLKRARKELQAYILGGVLPIVSHRNAVYMNNEISGIEVDEEIVAMYEGTTR
KEAQKLAVDISCKTMDEMRPYIDGYYLITPFNRVEIIADMITYIHKQ
>A0A7X8PMM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MNAGLQLEMNFDHGINRFQNCLDNGVFSLLVETGAPALDTELEHAAERLKNLEAAASAVS
VLPTSLAITDKYLYYDCWNICDFISALPSERRDRHVVYLSGFGTSPDQLLETANICVAKG
FRNLVPVSGNIRPGDQEADVRGRDYTESVTLLKLLRNQNNARIFSGTAVNPFKYTKDACF
GNYYKLIKKLNMGAGFMVTHLGWDLAKLQELRWYLSSRGMYYPAIARLWMLTQDKMEKIL
RGEMPGVVLPGSLRKILEAEFRYSSTQFEAAQWRRLQLYAAGCKLLGFSGIQVAGIDTPE
KLNIAVQRIAAGLHEFDTFYQWRAAYREHLGQIDLSPYPYSFYVFEKLLSNQHPQGEFPQ
MRVAKTPVPGIGEKIGDFLRRFMFFQANNQAPNERYILKKLMAGCHACSACRLPQTMYIC
PEKCPKGLANGPCGGTRPGGGCELSTVRECVHLRIARHAILRNEADMLEDDFVFQSTLRN
KKNGVE
>A0A8C1BIV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGGMNTLAADRQNLTGLLQLMAK
GMSEPIKDNDAAIRNYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAE
DPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELT
DYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLA
PETNLLKDELEKVNRRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSEN
VTALLQVLKKYEPRVNYHIVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFM
YWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFT
ES
>A0A7K9YJZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odontophorus gujanensis|TrEMBL
MVNENQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQESGDR
WFSLEFFPPRTANAAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEIHGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETSLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6G8TE41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula sp. JP-L23|TrEMBL
MSLRSRTMTPQDGVENLLTNARFELMPFDSFEEEITHLPDGATIAITTSPQLGIEATLER
TEEAVEQGFEVVPHIAARYVRDREHLADIARRLTEAGITDIFVPGGDREEPEGEFESAYD
LLSTLDGMEYSFEEVGITGYPEGHDFIDDETLAESMEQKAPYATYIVTQLCYDPETVLEW
IEEIRERGITLPVEIGIPGVMKYKRLLQISQKVGVGDSIKFLRKTTGVVGFIRQLIGSRG
TYKPDDLIDGLAPYVDDEEYNISGVHIYTFNQTPDTMSWRYERLEK
>A0A8H8RTG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnellula subtilissima|TrEMBL
MEKITDKIASLPPGTSYFSLEFFPPKTAMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
AEKSLELAELCQRELGLTTCLHLTCTNMSKELVDKALEDAKALGVRNILALRGDPPRSNE
YGTETAVEVEEFEWAIDLVRYIRKVYGDYFCIGVAAYPEGHADESHPEGQSVEHDLPYLV
EKVKAGADFIMTQLFFDVEAYDAFEKRLREHESGIFKTVPIIPGMMPIQSYQMIKRTTKL
SHAKMPPSIMERLDVVRGDDELVKKVGVDIVKRTNLIPASPPDPDSEYAIIDLPLQLDIN
GSEPSQKKPSRRQSSVGSDPYNRIIITASSTSHPSHEATASEAGQPAQAVNTRANTLAIS
EGEGTLGREATWDDYPNGRWGDARSPAYGEIDGYGVSLHMSTNQAVKLWGYPTSISDITA
LFIKHIEGSIPAIPWSEEGLNEETSTIKTQLLALNQKGWWTVASQPAVNGVRSSHAVFGW
GPKNGFCFQKAFVELFIPSSSFPSLLQKLEDSEEVSYYASNAKGEFKSSGNGGANAVTWG
AFPGKEIVTPTIIEEVSFRAWAEEAFGIWAEWGRVYGRGREESRAVVEGCMGDVWLVNVI
HHGFVEKDGLWELLLN
>A0A8C2L0Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGKDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIITQLFFRAETFLKF
VKDCRAIGISCPIVPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNCRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQED
>A0A849KCR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramlibacter sp. B156|TrEMBL
MLPISLEFFPPKTAEGSEKLRVTRQQLYALKPEFCSVTYGAGGSTHAGTFTTVSEILAEG
VDAASHFSCIGATRAKVCDQLAQLKAMGVKRIVALRGDLPSGYGMGGEFQYASDLVAYIR
SECGSDFHIEVACYPEVHPQAKTPQSDMDAFVTKVRAGADSAITQYFYNADSYFRFVDEA
ARRGVTVPIVPGIMPITNSSQLLRFSDACGAEVPRWIRLRLQSYGDDAASIKAFGQEVVS
DLCRRLVAAGVPGLHFYTMNQARATMDLCEALGRC
>A0A7X6ZGV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
VLSLLSGLEPVMQMVCRDRNRIAMQGDILGAVALGIRNCLCLSGDHQSFGKVGKLIGHPG
AKNVYDIDSINLIAMLKGMRDDHKFLSGDPVKSDMPLFIGAAWAPLAEPVDFRVIRLAKK
VAAGADFIQTQSVYDVERFANSLKMAREMGLHEKTAILPGVIVPRSARMLTYMNENVPGV
TVPKSYIDRMSETQDPKGEGIKIAIELVNDLKSLDGIRGVHIQAIEWESAVREITSGTGL
LPRPEVVDAG
>A0A7V6HGX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MTFFEKLQSGHPTISFEFFPPKTPEGWARLYATLAETARLNVDLVSVTYGAGGSTRENTV
DLVASLQNNLGLHAMAHLTCLGHSQVDLSRILDRLAEKNVPAIMALRGDPPQGESSFRPH
PYGFAYASDLIGFIRDGWPQFKIGCAAYPEGHPESFAEGQPRSPARDITFLKRKQENGAD
FAVTQLFFSNSAYHDFVAQARDAGVTIPLLPGIMPLSSAKQIERFVELSGCSIPDALRQA
AAAEDVEEAGFCFALDQCRDLLAHGAPGIHLYTLNQSSLSGRIFAALRAENAGL
>A0A8C1WAJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MCIRNMVNQRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIE
SGDRWFSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAS
TAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGKDWVEEDGGFNY
ATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIITQLFFRAE
TFLKFVKDCRAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAI
RNYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAH
PKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPK
EALLQMWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKV
NRRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEP
RVNYHIVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQ
WAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPQETQEEGS
ES
>A0A2E0NGJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coraliomargarita sp|TrEMBL
MSDCPIKLRFKSKKPLFSVEFFPPKSEVAAKKXFETARQIKPYNPDFASITYGAGGSTRT
RTLQYASHLHKDYGYTMMPHLTCVGHSKAELRSIVQEFKSAGHHQIMALRGDPPTGNDDF
MPHPDGLSYASDLVKLIREEHSNCIIGVGGYPEVHPEAPSAEIDIINLKHKIDAGADLIT
TQLFFDNCAYFNFKQNCKRHGIEVPILPGLLAVSSLEQAQRFCAMCGSVLPAKLKKQLED
AHSDRVACQKIGSDWVFSQAKELLENGAPGIHLYILNQAKPAIDLMDRLQSIGFYS
>A0A5Q0EI74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium SS-5|TrEMBL
MFSIELFPPKTDAGMEKLQAAVGELLPLGPEYVSVTYGAGGSTQGRTFATVDWLVSQGVD
AAPHLSCIGSDRAEIGAILDRYQQQGIRRLVALRGDLPSGAGLGGLGELQYANELVAFIR
QRHGDWFHIEVAAYPETHPQASGAEADLRNFQRKVQAGANAAITQYFYNADAYFHFVRRC
RAIGLDLPIVPGIMPISNYSQLARFSDACGAEIPRWIRRQLQDCGDDLERIRAFGLEVVV
DLCQRLLDGGAPGLHFYSMNQAGPTQAILGRLS
>F1TBP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MRIQEIFAKKKPVLSFEIFPPKRDSELKDIDETLAILSKLSPDFISVTFGAGGSSNNNKT
IEIAKKIKHQYGIETLVHLTCSGYTKQEIDSFISILSENGIENILALRGDKNPNVLEKSD
FQYASELTGYLNKSANFCIAGACYPECHPESKNRISEISHLKGKVDAGSDFLISQLFFEN
EFFYSFIENCRIAGINVPVTAGIMPVINKAQIERIVNLCGASLPNRFRKIINRYENEPTA
LFDAGMSYALSQVIDLLVNDVDGIHLYTMNNPIVAKRICEGIKNII
>A0A3D8M3Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas aestuariivivens|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPNSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVSAAPHLTCVDASRDELRQIAKDYWDSGIRRIVALRGDLP
PGVDKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTSVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLLKFAGFTNVHVPGWLHKMFEGL
DADDQTTRNLLGANIAMDMVKVLAKEGVKHFHFYTLNRSELSYAICHMLGLRAG
>D5T142|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc kimchii (strain IMSNU 11154 / KCTC 2386 / IH25)|TrEMBL
MTKISEIYHTKSSPVLSFEIFPPKKESGITSLYQTLDEVNPQKMGVDYISVTYGAGGSGD
NTMTRDLAQYIQTHFGVTALHHLTGVNQTPESLRDNLAKIKQAGIENILALRGDLPDSDY
VNADYPYAKDLICDIKQASTFNIGAAIYPEGHVDNPITGISVAGIKEKIASGTDFLISQF
FFENDVYYHMQEALKNNYIKVPVSAGVMPIISKAQVERMTYMIGSSLPARLVKMIHKYEN
NSDDLKKAGIEYALEQIQDLLDHGVDGIHLYAMNRPNVLKSMLPIINQEIESKHF
>A0A1R0Y8M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus odorifer|TrEMBL
MTPPKASHSPEKISEIAQKQVERLKNVDLDALILYDVQEEAERVDHERPYPYLPTIDPAI
YGDKYLGQVEVPKIIYRCVGNDTRASFADWIKTDESEDRFSVYVGASSSKQEVKLNLPDA
YKLSKQLNSNLNFGGVVIPERHIKKNDEHTRIVEKINNGCSFFITQATYNVEASKNLLSD
LYYYNTNKGFEMVPILFNLAPCGTAKTLQFMKWLGISIPGWLENELKYSNDILDKSIQLS
QKIFEELFEFGLEKGIPIGCSIESVSTTKLEIEASIQLAKDVKAFLDKKLLSLESR
>A0A1F8NH58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_68_17|TrEMBL
MKPRSRLERVLRSGRFAVTAELNPPDCGEAQCVYDRALVLASVCDAINATDASGANVHMS
SVGVCALLTRAGYEPVMQVSCRDRNRIAIQGDLLGAAAMGVRNLLCLTGDGVQAGDQPQA
KPVFDLDSIMLLRTARIMRDQGQFLSGRRIESPPPFFLGAAANPFAPPFEHRARHLAKKI
EAGAEFIQTQWCFDVPRLREFMAMAGDLGLPERAFILVGVGPLRSARAAEWLRSRVPGVV
IPDEVVGRLRRLPTDKQQQEGKRLCVEIIQQVQDIPGVRGVHVMAFRQEELVAEIIEEAG
LLPRRRGTAGATAGPPSED
>A0A1E3W8Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloceanibacter marginalis|TrEMBL
MDVSFEFFPPKTDAMEDTLWRSIRRLEPLRPKYVSVTYGAGGSTRERTHATVGRMLRETT
LKPAAHLTCVSATKEEIDEVIRDYWDLGVRQIVALRGDPPGGVGACYERRPGGYANAADL
TAGIKKIAPFEISVGCYPEKHPESKSVEADIDMLKAKIDAGATGAITQFFFDNEVYFRYL
DRVRAAGIDIPIVPGLIPIHNFKQVSSFAERSGASVPDWIGHRFEGLDEDQETRHLVAAA
VAAEQVLGLVDQGITEFHFYTLNRADLVYAICYLLGLRPAKAFTEAKVETAT
>A0A7W6MAM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter noctilucicola|TrEMBL
MPTPNVSFEVFPPRNVDAAFNLWDTAHTLAPLNPRFFSVTYGAGGTTRDLTHDAAHVLRR
TSGLPVAAHLTCVGASKTETLEVADNFAKIGVTDIVALRGDPQDGADTFTPHPEGFADSC
ALIEALADKGTFNIRVGAYPDSHPEATDMAANVAWLKRKFESGADEAITQFFFEADSFLR
FRDACAAAGITKQVTPGILPILNWKSARKFATRCGTPVPAWLDEAFDAAIRDDRHDLLAT
ALCTEMCDTLIEEGVEDLHFYTLNRAELTRDVCRALGVTPQVAVRNVA
>A0A8G0MW20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. sptzw28|TrEMBL
MLKEKIVNKETGIITYGITPPKQSNTPEKLAEISQKLIERLKDLDIDGLIIYDVQDEAER
TTQERPFPYLQTIDPTAYSKEYLSELEVPKIIYRCVGKYTETQLSEWLTSDAEQDRFSVF
VGASSSKQEVRLGLPEAYSLSKRLNNELVFGGVVIPERHLKNNDEHLRIANKVRNGCRFF
VSQATYNVEASKNFLSDYYYYCQNNEIEMVPILFNIAPCGSQKTLEFMKWLGISIPRWLE
NELIYSNDILDKSIRLSQEVFEELMDFGLEKGIPIGCSIESVSTRKVEIEASIQLVRDVK
YSMEQKLIQKR
>A0A7C6AZT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSKLNFAEHFQQGVVVFDGAMGTEIYRHHVFTNRCFDELNLSDPKLIEKIHQSYCDAGAE
VLTTNTFGANRETLSKYGLGEQVVLINRAGAQLARKVADHAGRPVFVAGSVGPLPTLPSS
EADFAGLIGEQVDALMEGGADFIIFETQPSRKAIEMCAAAMRTREHIPFVLSLAVYEDGE
TGSGENIQRLFAPLPEGCPQPIAWGLNCGSGPHGLLSAVEQAIRLINRPLIVQPNAGIPK
EVEHRRIYLCSPEYLAEYGKRYVNLGAAAVGGCCGTTPDHIRALCDAVKPLVRARVKPVV
VAAEPVELKTPVPLAERSRFAWRLVHKQWVTSVELVPPRGFDLRDIIEKSKSLHRHGVDA
INIPDGPRASSRISPLITADRIQREAMIEVILHFCCRDRNLIGMQADLLACAACDIRNIL
FVTGDPPKLGNYPHATGVFDTDSIGMVGPKAAQPGSGYRGTVDRSPHRCRHRRRFGPDGH
RREARVGSFPPEGGSRGGIRHHPARLRSRGAFAVPG
>A0A7C5BWC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MTGAELKDLLLRTVLVFDGPMGTEIYRRHVFLNRCYEELNLSEPDLIRAIHRDYCAAGAD
VLTTNTFGANRLSLRRFGLAEKTVPINRAGVQIAREVAQASRRDVLVAGSVGPLGTDPFS
QESPEEVLREQVSALVESGVDFVLFETQRTRQTLELCAQVMREFPQVAFVLSLAVEENGE
TAQGEPIEQLVGNWPENLPQPAAWGLNCGTGPSGLLTVLERLLRLTNLPVIAQPNAGVPK
QVDYRMIYLCSPEYFTEYGKRYLSLGARGIGGCCGITPEHIRELAQAVKALARAARGTSV
LVQPVSEVQPKEPVPLEKRSSLGWRLAHRKWVTSVELVPPRGWDLGPIIEKSRQLHAAGV
TAVNIPDGPRASARISPLVTAAKIQQEVGIETILHFCCRDRNLIGMQADLLGCAALGVKN
ILFVTGDPPKLGNYPHASAVFDTDSIGMVALQRRLNSGIDLGGQPIDPPTQAVIGVGVDP
TAVDRRRELDRFRRKIEAGAEFAITQPVFNPDALLRFLEEVADCAIPIVAGIWPLASLKN
ALFLKNEVPGVEIPDWVLERLAAEPTREGQLAIGIEIARQSIEKIASCVTGIQVSAPFGR
IEIALAVLEGWLEPCTSSATTESLESKGASG
>A0A7V5TP22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTAERTDEYKSGSNLEKILRAGHFAVTGELGPPQGADAEVIHRKAQLLAGVVDAVNITDN
QTAVARMSSIASGVLAMQDGLEPVIQMTCRDRNRLAMQSDLMGAYALGARNVLCLTGDHQ
SFGNHPTAKNVHDLDSIQLIQMVRRMRDEGVFQNGEQIKAGVPRFFIGGAINPFGDPFEF
RPYRLAKKIAAGADFVQTQLIYDIPRFREFMKRVVDMGLHEKVYILAGVGPLKSSGMARY
MRDQVPGMIVRDEYVDRMKGAIAGIPKEDKKARRKAWREMGIKICIEQIQEIMEIEGVAG
IHIMAVEWEAAIKPIVEGAGLLPRPQVE
>A0A3M1H3J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MQRNFVHTKRFIQVRRKNLSRTETEKRTNFLQRLEKDIIIFDGGMGTSIYTKGIYINRCF
DHLNLTDSDMILEIHREYIEAGAEAIETNTFGANRIQLGEFNLADKVYEINYEGAKIARE
AGGEHIFVAGAIGPLGIKIEPWGEMSVEEAREIFREQVEALYKGGVDCFILETFSDLNEI
HQAILAVKEVCSLPIIAQMTIDRDGSSLYGTPPEVYTKRLDEWGADVIGLNCSVGPASML
DTIEKMMKLTSKKLSAQPNAGMPRNVKGRNFYLCSPEYMGKYAKYFIQRGVRIVGGCCGT
TPEMIQAIANAVRAYSPTRPRAQVLSPSQSMMDSVEVKPVPQEDKSNFARKISQKEFVTS
VELNPPKGFGLERTLKRAKLLKEGGVDAINIPDGPRATARMSPMAMAVRIEQEVGMETVL
HYCCRDRNLLGMQSDLLGAAALGLRNILVITGDPPKLGDYPNA
>A0A7Z9LD46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MEIWSPDSSVVLELVPPTLKKGEEGIRRRLKRLEGRLEAYPFDAINIPEIREEASRSGGG
SRTSGFEPRHEARALGRLIQERYDIPVVINHVVVHAPEAEFRIWLRQTRDEYGLENLILV
GAPTDEEFPGPSVPVANAIAREELGKRGQIGNISIPGRETPAQEVERMEAKADSGADFFS
TQIVYDAGEVTRLLDQLSIGPSRVADHPLLISLCPIRRPSSITFLRYLGVEISELLEQRL
VGDGKGILERSIDHIACLWEEILEYRRERRPQWPIGWNIAPVGPLPQGATRRLLERLGEM
IPGS
>A0A7C8D0K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MYGTGEPVFSFEFFPPKTDEGAKNLMKTVAALKGKLSPHFVSVTYGAGGSTRDRTLEVVA
NIQNDLSITALAHLTCVASSRGDLREAMRRMITENVENILALRGDIPSGEGEFVPPEDGF
RHASELIDYLANNYFVDIGAACYPESHPESDSAESDMQWTKSKYDLGANFLITQLFFDNS
HYFDFVERARAAGVKAPIVPGIMPITNVAQIERFTKMCGATIPEELQERLARIADDPAAV
MATGIELAIDQSRELLDKGAPGLHFYTLNKCDATRSVLAALR
>A0A7Y2DA94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrinomonadaceae bacterium|TrEMBL
MKDFREILENDSVYVFDGAVGTRFYDKGIYINKSYDELNLIAPDLVREVHEEYVAAGADV
IETNTFGATRHKLQHHGLDDKLHEINVSAAKIANRAAGESAFVAGAIGPLDLRIEPYGPT
SLDEAKEMFKEQIAGLLEGGVDLFILETFADLSEIQQAIKAIKETCDLPIVAQIQIQTDY
KTVFGATSDIFTKRLDEWGADVIGLNCGVGPNHILTELEKMRELTDKKLSAQPNAGLPRD
VQGRQFYMCSPEYMSEFARRFIQAGARFIGGCCGTTPNHIKLMSASVRSLSPRQTKVTVK
APVVSKKVKETVEVEPVSPLDRSNWSRKVAKGEFVTSVEVLPPRGVSAKRTLRSIGLLKE
AGVDAVNIPDGPRAQTRMSAQATAVLVEEKVGIESVLHYCCRDRNLLGMMSDLLGAAALG
LHNLLIITGDPPKMGPYPDATAVFDIDSIGLTNMVSKLNHGLDLGNNPIGEPTAFSIGVG
VNPGAMNLEEEIKRFEWKVEAGAEYAITQPVFDIEQLREFLERIEHVRIPIIAGIWPLVS
FRNADFLHNEVPGVRVTQEILDRMRVASDKGKEFAREEGLTIARESLEEIRESIQGVQVS
APFGKVKLALRVLEGLPQFADAQKATSSGD
>A0A0F4Z248|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rasamsonia emersonii CBS 393.64|TrEMBL
MHVGSKLLEEEASGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGGRRA
ELTCEMVKVAQTVYGLETVMHLTCTDMPREKIDAALEAAYNAGCTNILALRGDPPREREK
WEAAEGGFRYAKDLVRYIREKYGNHFDIGVGGYPEGADDNRDVDLLIDHLKEKVDAGSSF
IITQMFYDVDNFLNWVQKCRDRGIKVPIVPGIMPISTYSAFIRRSNWTKIRIPPEWLEAL
EPVKNDDAQVRNIGTQLVADMCRKLLNSGKIHHLHFYTMNLAQATRMILEELKLTPSEEM
PLYKPLPWRQSLGLRRRTEDVRPIFWRNRHTSYIARTQTWDEYPNGRWTDSRSPAFGELD
TYGVGLKGTNEENVKLWGEPQSLKDLSDIFIRYLEGKLERLPWSDTPITAETDVIKPDLI
DLNRRGFLTINSQPAVNGAKSSHPVYGWGPRNGYVYQKAYLELLVPPDVVGELIARIEKN
DDLTYYCVSKTGELRMRNGEGPNAVTWGIFASKEIIQPTIVESISFMAWKDEAYLLGDEW
AKCYPAESASRKLIQRIMDEWYLINIVNNDFHKTHDIFHLFQGLSVKNIDQRVEAEPADG
EAATNAASA
>A0A3E0PZX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRISEIYQPGEFGLSIEVFPPKTPKGDAALWETIERLTPYRPAFISCTYGAGGTTRLRTI
DICREIQERFELPATAHFTCVGSSRDELREWLDSAAAAGIGNIMALRGDPPQGMEEFRPA
EGGLTYANELVALIREQSKEFGIGVAGYPEKHQEAPDPETDLTNLKRKVDAGADAVFTQL
FFVNENFFRFREAYEQAGIRVPLIPGIMPITEFARIKRITAMCGAIFPDELASRLEAVQD
DKEAQFEIGVEHAIRQCRELIDAGAPGMHFYVLNKSQACERILDALGVETSCE
>A0A3M1HMH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
EYAITQPVFDVNLLEKFLEELDKRNLRIPIIAGIWPLASLRNAEFLRNEVPGIVVPDEVM
KRMEEAEKKGGAGEEGILIAHEAIEKARPFIEGVQVSAPFGRAKTALKVLSILKK
>T0GI25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira broomii serovar Hurstbridge str. 5399|TrEMBL
MKKILEIYTNAKEPVYSFEFFPPKTIEGEAKLYETVKELSRVNPGYITVTYGAGGSTRDK
TIRLTSDLAQKFNLAAAAHFTCVGGNKEEIHNILKEIASSGIRNLMALRGDPPKGEGVFK
KVEGGFEHASELISFIKSEGFDFCMGGACYPEKHPQASDLETDVDNLKKKVDAGAEYLVS
QLFFKNEIFESFLNLVRKKGIRVPVVPGIMPITSFSQIERFRSMAACEFPDKLLTDLEEV
QNRPEEFYRRSLNFSVEQCRELIEMGSPGIHLYTLNQSHASYDIVRELRGEGK
>A0A5C8CAW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicycliphilus sp|TrEMBL
MNAANAAPAAVPVSFEFFPPKTPEGIEKLRAVRQQLYALQPQFCSVTYGAGGSTQDGTLQ
AVQAILDEGQQGASHFTCVGASRDSVREKLALFQSMGVRRLVALRGDLPSGYGSMGEFRY
AADLVAFIRAETGDHFHLEVAAYPEMHPQARSPEADLQAYAAKVKAGANSAITQFFFNAD
AYFRFVDEARKLGADVPVVPGIMPITNASGLLRFADSCGAEVPRWIRLRLQGLGDDAAGI
RAFGLDVVTHLCEQLLAAGAPGLHFYTMNQSTAVLEICRRLGLAGAGTR
>A0A3D4FA47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRQIRDIHQQRKSEGKPAFSFEFFPPKTEKGEEALFGSVLPELQTMAPDYCSVTYGAGGS
TRDKTLDMVERIQKDFGLVCMSHLTCVQATKEQIAQVLQDAEKRNIRNILALRGDPPGGV
GPFEATEGGFAYSKDLVAFIRAHHEMSIGVAGFPEGHIACKEGKEVDWGRLKEKVDAGAD
FVVTQLFFDNEDFLRFRDHMVKELGMHQTLIPGILPVLSTRQIQRFTELCGASIPTPMMQ
RLEDLSEDDAAAAAFGIEYAVGQCEELLKEGVAGLHFYCLNKAHSTLEVARALASHR
>A0A3D0XL16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRQIRDIHQQRKLEGKPAFSFEFFPPKTEKGEEALFGSVLPELQTMAPDYCSVTYGAGSS
TRDKTLDMVERIQKDFGLVCMSHLTCVQATKEQIAQVLQDAEKRNIRNILALRGDPPGGV
GPFEATEGGFAYSKDLVAFIRAHHEMSIGVAGFPEGHIACKEGKEVDWGRLKEKVDAGAD
FVVTQLFFDNEDFLRFRDHMVKELGMHQTLIPGILPVLSTRQIQRFTELCGASIPTPMMQ
RLEDLSEDDAAAAAFGIEYAVGQCEELLKEGVAGLHFYCLNKAHSTLEVARALASHR
>A0A2D5W6N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MPGGAHDHGLRAPGDNGEDRCAGCLPRTLPTDSRTGGGWGVRIADIYGAGTGPVFSFEFF
PPKTERGAANLMETVADLKAALAPDWVSVTYGAGGATRGRTLEVVSAIEAELGLTAMAHQ
TCVAASSADVEANVAQLKAAGIENILALRGDIPKEGAAPSEDFSHATDLLEFLGQRFEGC
LGAACYPETHPEAQSPAADLGYALAKQELGAEFLITQIFFDNRHYLDYLGRARELGIIIP
IVPGIMPITDVAQIERFTEMCGSEIPQELTTRLRRHAADPAVVMATGIEHAITQCRELLA
AGAPGVHFYTLNKSHATRSILAALRG
>A0A4Q5U9N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTEHLQQAQGRTLVSFEILPPLKGKGINALWEHLDPLMEYHPSFINVTYHRSETMFKR
TAAGTFDKVEVRKRPGTVGICAALQNRYKVDAVAHLICGGFSKQETEDALIDLHFLGIDN
VLVLRGDAPKNEAVFEPEPGGNAYAIDLLHQVQRMNDGIYLEEDLKNAVKTDFCIGVAGY
PEKHFESPNMRTDLAWLKAKVDAGACYVTTQMFFDNQKYFDFVKACRDAGIDVPIIPGLK
PLTSRKQLSIIPRTFHVDIPEDLASAVLAARTDADVERIGTEWLLQQSRDLKAAGVPVLH
YYTLGKPRVIAEVCKEIA
>A0A2G2NVJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibacter sp|TrEMBL
MKVTEHIEQANGNTLFSFEIIPPQKGQNIQQLYDNIDPLMEFNPPFIDVTTSREEHIYIP
KGNGLLEQKITRMRPGTVGVCASLKYKYNVDTIPHVLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDAMKHEQYFKAANGGHQFATELVKQIKDLNKGTYLHEIIETPYKADFCIGVAGY
PEKHLESPSLESDLKRLKEKVDAGADYVVTQMFFDNKKYFDFVKKAREIGITVPIIPGIK
PIAIERHLHILPQVFRLDLPECLIKEVEKCKNNKEIRHVGIEWAIQQSKELIKANVPVVH
FYSMGKSDNIKAIAASVF
>A0A5C7YZ78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp|TrEMBL
MTLPVSFEFFPPKTPEGAEKLRAVRQKLYALKPEFCSVTYGAGGSTQEGTFATVGEIIAE
GVQAASHFSCIGATKASVRAQLATLKGMGVKRLVALRGDLPSGYGAGGEFHYASDLVAFI
RAETGQDFAIEVAAYPEVHPQARSPEADLNAFVTKVKAGADSAITQYFYNADAYFRFVDE
AAKQGVDIPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQAYGDDIASIKAFGLEVV
TDLCQRLTAGGAPSLHFYTMNQSAATTDILSRLKGA
>A0A4Q5YN31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTEHLAQGKDRTLVSFEILPPLKGKGIKSLWEHLDPLMAYKPAFINVTYHRSESTFKR
KADGTFEKVQIRKRPGTVGICAALQNRYGVDAVAHLICGGFSKQETEDALIDLHFLGIDN
VLVLRGDAPKNEGIFTAEPGGHHYASELLEQVMRMNNGQYLEEDLKNATRTDFCVGVAGY
PEKHFEAPNLSADLSYLKAKVDAGACYVTTQMFFDNKKYFDYVNACRAAGINVPIIPGLK
PLTTKKQLTIIPRTFHVDIPEELSNAVLACKTDAEVEQVGAEWLLKQSQELKAAGVPVLH
YYTLGKPDVIAKVVKEIV
>A0A366IJ00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium celere|TrEMBL
MSDSTILSLLESARYEVLPTSGIAERISDSVDPGRVITVTASTGLTLEATLATAEQLQSL
GFTAVPHVAARMVHGRSELAEVVDRLRTAGITRIFVPAGDATPPAGDYSGALDLLVDLSG
LDADFLDVDVAAYPESHPLISDEVTIQAMADKRGYASHLVSNLCFDPDTVESWLHAVRRR
GIDLPVHLGVAGKVELGKLAKVATKIGVGESTKFLRKNVSTFARMAKPGGYNPRKFLDRL
APVLDDPALGVAGLHIYTFNQIKDTEEWRRKQVEKLSD
>A0A2N0L8L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G3|TrEMBL
MKVFDNDINYSQLRRSVLMPSVTELLTQPRSRPFVVLDFSPPRGGIPHLLSDAFSLTPDL
FSIAYNPGKSVRANPIMVAHWIQNHTGIPAVFTLATRDMNKKALQGILLGAQLIGLDNVV
SVMGDELKGSEKLSQKTISDFTASGFVSSIKQMNTRVDFRDRFLRYPTGFCVGATIDLSR
DWSGEIPLTRKKVTAGADFFLSQPVFDTSQPEQFMERYFKETGCRLETPVMWGVQVKVQD
SVSLVPVPDWVHNDLEQGRSGFEIALQIISEHTDYGFDTFYLVPPILRGGTRDYESAQAV
IDEL
>A0A2E9EVE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHITDIINKGRPTFSFEFFPPKSERASESLFETIKDLESLAPSYVSITYGAGGTTRERTH
DLVEKILETTSLTPIPHLTCVQHTEEEISNILKRYSDKGVSNILALRGDTPKGETQYNRS
NDSFYFARDLVEFISAFNTSTLGKESKSFGIGVAGFPEGHPETPNRIKEMDHLKAKVDSG
ADYICTQLFFDNHDFFDFRDRCELAGINIPIIAGIMPVTSISGMQRMADLAAGSRFPAKL
LKSIDRCNLDSSAVERVGIQYATEQCSDLLNNGVDGIHFYTLNKSKSTRGVFEALGINKT
>A0A0D2WUQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsaspora owczarzaki (strain ATCC 30864)|TrEMBL
MLNLVQAAESAARNPPPSSSSSATFADPRRGFCSFEFFPPKTDAGVANLMERMERMVAAG
PLFVDVTWRSGGETSAVSLAIAKAARQLLGPDRVMLHMTCAGASKATLVSHLATAAAAGV
QCILALRGDDLDDFEEQNNAPFKYAIDLVRLIRSEFTNKFTVAVAGYPEGHGGIGYAVNL
KHLKEKVDAGADFIITQMVYNAEVFLQFLQDCRGIGITCPIIPGIMPITNYQQFIRIISL
TKVMVPDDLLDALRAVKHDDAAVRDIGSSFVLQLIQQFQNAGVFGVHFYTMNLEEPVVGL
AETAGLLDPASVKIRSSEQQELAGEVRPIYWQHRPTSYMVRTSDWSEFPNGRWGDHQSPA
FGDLSDFHLAAVHPPTVSPRHAIIQKELDTDITICRRLKTEQDVFEVFAKYVQGDIPMIP
WCSNPLDSETSSISQRLANLNRHGILTINSQPAVNGVPSTDSVFGWGPADGLVYQKAYVE
FFCDSQRLDKLERVLSAHRHLTLHAIRADGTERVGATNHTTALTWGVFPNREIVQPTIMD
PVSFRVWSTEAFTLWQRHWARLYPASSTERALLSTIAHSYWLVTVVDNNFVASTLFDALD
QVVMA
>A0A176U7C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium KLE1615|TrEMBL
MKVNEILSNGKITLSFEVFPPKTDAQFESVRQATIDVAALKPSYMSVTYGAGGNTRKNTV
AIAKGIQDTTGVTTIAHLTCVGATKENIHNTLDEMKAAGIENVLALRGDRPRDFEGDPFV
DFHYASELVSEIKAYGDFCVGGACYPEGHVEAANKNEDITNLKKKVDAGCEFLTTQMFFD
NNIFFNFLYRVREQGISVPVIPGIMPITRAKQVETARDLSGCSMPQRFLNLVDRFGSNPK
AMEQAGIAYATDQIIDLIANGINHIHVYSMNKPQIAEAIQKNLSEILK
>A0A3L7Q7J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MTASFEFFPPRTDAAWNEFVASLPEFEALQPSFVSVTYGAGGSTRDRTDALVTRLATDTT
LAPVPHLTCVGHSTAEINQILQAYA
>A0A2B7YIL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. polymorphum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEEVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHFTCIGSKKEEIDRVLENLERNNIENILALRGDYPVDRELEPGD
FNYAKDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRK
>A0A1Q7NXV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium 13_1_40CM_2_68_13|TrEMBL
MPHAFDRRLAAGPLLCDGAMGTLLYARGVSIDACFDVLNVSQAKVVQSVHSEYIAAGADC
IETNTFGANRFKLAVHGLASDVHQINLRGVKLARDVRESMGRDVLVLGSVGPLGKYLAPL
GTVTADEARAAFREQAEALLEGGIDAFVVETFSDLTEIALAIETIRTLTDLPIVAQMAFT
DEGVTFAGRSPAEVARTLRELGVRALGANCSVGSSTLYEVLEAMGPEARDVPLAIQPNAG
LPHRIGERLMYLSSPGYMADYAGRMIDAGARIVGGCCGTTPQHIAAMRRVLDARAPASKA
EPRPTSAARVIEALETPGLRTTLAPTLLGRKLEQRSFVVSVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLPTAILVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALGIRNILAMTGDPPRTGDYVNATAVFDVDGIGLLEVLRRMNEGMDATGNGIGEPTSFCV
GAALDPGAPDPGREVERFHRKLEAGARWFQTQPVYDLEVLDRFLARVVGSPVPVLVGVLP
LHSFRHAEFLHNEVPGITIPDGVRARLRAAGDGALRAGIDMAQQLVGEIRSRYAGAYLMP
SFGRFEVVAEVLDVLR
>A0A6I6QDX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mediterranea|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASHNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRTLLARYKAAGIQRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVNKANSGANSAITQYFFNADSYFY
FVERVRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQRFG
EDVVTQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A7K4HG85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MTDVKTYSKLGEAIAKGEFILTGELEPEKTTDLSHTIHEAKEMAPYVIAANVTDSPLGIV
TINSMAATHLIQKAAGLECVWQMTVRDVNKLGIAGMIMGAHALGIRNVLSLTGDHTALGD
MPESKPVFDLDSATLVKLVREMVDKGSINGNEIESPPTLHVGAAANPNAEPMGAEILKIG
RKAEAGCEFIQTQVVYDLDRTIEFLTEIKKYNVPILLGIFPMKSYGMAKGFDTFVPGVSV
PKDILAKWKSVKKEVTDKKEQKKLYDQYNYEFFKPFITELRKKNLLAGIHCMAVHYPRIF
PKLKDIIEN
>A0A5C9EDV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MSNRPAYSNLMKKIKEGHFVFTGELEPKKILDMEEIIHSAKEMKKTKRIVSANVTDGPQG
DAYMCSLVPSYLVQRDAEIEAVWQVTVRDRNRVALFGDVLGAAQLGIKNILTLTGDHTAL
GDHKKGRAVYDIDSTQFCQMLAIMIDEGTDLEGNELKGGKIEMNYGCVANPNSDPREPEI
LKVGRKVENGVDFIQTQTSFDIEQAKEFLKELEQFNVPVLLGVFPLKSYGIAWYFDNYIP
GVSVPKDLLKALKKAEKDNKGDKKGKYAAIDKINIEFFEPFIKEIQKSTKAAGIHCMAVE
YERLFEPLLSDFPQYVE
>A0A6N7Z637|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis pithecellobii|TrEMBL
MITDAVAELVQAAHIEVIPLLGSEEAMLGAPPAVPITITCSPKFGLERTLLFTEIAAAAG
RRVIPHLAARQVRDETMLREILDRLGAAGVPELFVIGGDATEPAGTYAGSAELLEAMSGL
PHGISRIGVGCYPEGHPAIPDDRLLADLLHKQKYAGYMVSQLCFDATALLRWISSIRAAG
VTLPLRIGVAGPVQMRKLIELSMRIGVGSSVRYLTKQHGLLGQLFRGSAYRPERLLARIF
DGTSVTSSGIEGLHVFSFNQLALAAGWQRRIAASADGAELA
>W1U4V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium butyricum DORA_1|TrEMBL
MIKEFLNNNILICDGAMGTYYSEKTGNDISYCEFGNLNDKNTIRRIHEEYIEAGAKLIRT
NTFSANSKELGVSRKTLKDIIESGIEIAKEAVYNKEVFIGASIGPIRENGADENFVEVLE
EYKFIVDCFLDNNINVFIFETLSNLDYLEEVSTYIKNKKPESFILTQFAVKPDGFTRDGY
SVSKIVGEVKKINTIDSYGFNCGSGPTHALELIKKIDIGDDIVSSLPNAGFPEIIHERTV
YPNNPVYFARKVKEIKKLGVSIIGGCCGTNPSYISKLRETIDKKPEAGDKIKRYEHETYN
EKNIIKNTFKEKVENGDFVIAVELSAPVDTDINKIMTGAKVCKDNNIDIVTVPDSPMSKV
RADSVVMSSKIKREIGIEAMPHMCCRDKNTNAIRSSLIGGHIEEIRNILAITGDPISDAS
RIETKSVFNLNSFKLIELINDMNNEVFTSDDIFIGGALNLNVLNKEVEYGRMMKKVERGA
KFFLTQPIYDDSAVEFLKSIKERTDVKILGGILPVVSYRNAMFLNNELPGVTIPQEILNR
FSEDMNREEGQNIGIDIAVSMGKKLKGICDGLYFITPFGRVNMIVDIVNRIKEV
>A0A8G0Z404|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Bataviae|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TAQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A8C2UY35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chinchilla lanigera|TrEMBL
MDCGKARVLAAGPHCPSLGMWASRAGISRFSVPPPTSSAWAMVNSGEARGDGGVSSGSEG
SKDSSRCSTPSLDPERRERLREKMRRRMEAGDKWFSLEFFPPRTAEGAANLLSMFDQMAT
GGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETVLHMTCCQHSPEEITGHLYKA
KQLGIKNILALRGDPLGGQWESEEGGFDYATDLVKHIRSDFGDYFDICVAGYPTGHPEAD
SFEEDLRHLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQSYSSL
RQLVKLSKLEVPQEIKDVIEPIKDNDAAICNYGIELAVSLCQELLASGLVPGLHFYTLNR
KMATTTVLKRLGMWTEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQDWNEFP
NGRWGHSSSPAFGELKNYYLFYLKSRCPRQELLKMWGEELSSEESVFEVFAHYLSGEPNQ
HGYKVTCLPWNDEPLAAETSLMKEQLLRVNRLGILTINSQPNVNGKPSSDPIVGWGPSGG
YVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFP
GREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSRMMIQYIHDNYFLVNLVDNE
FPQDNCLWQVVEDAFELLNRPAGLSREAEAP
>A0A853BZA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides thalensis|TrEMBL
MRSKERATVRRLLTNARYEVLPTKTIEAKVLESVPTSVPVTVTASPSMGLERTIETAESF
AAQGYTVVPHLAARMVHGRTELEELATRLGAAGITSVFVPGGDADPVGDYKDALSMLEDL
TAIGSPFAHVGVTGYPESHPTIHDDLTVQSMWDKRRHATHIVSNLTFDAAVIKDWLQRMR
LRGIGLPLLLGVPGPVERTKLLSMATKIGVGDSTRFLAKQKGLMARLVAPGGFTGESFLE
KAAPTVGEPEMNVSGLHVYTFNQVAETEAWRQDWLKRLEG
>A0A4Q5X7N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MHLPLSFEFFPPKTPEGVVKLRAVRAQLYAMRPEFCSVTYGAGGSTQTGTFNAVREIQQE
GVQAASHFSCVGATRDTVRTQLAELKAMGVRRLVALRGDLPSGYGIGGEFQYASDLVSFI
REETGRDFHIEVAAYPEVHPQARSAEADMLAFAAKVNAGADSAITQYFFSAEAYLRFVDD
ARAKGLNLPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVI
AHLCERLQAGGAPALHFYTMNQSVATLGVLQRLGRAA
>A0A1Q3QCH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidia bacterium 43-41|TrEMBL
MKILELIDQTSKPVFSFELLPPLKGNSIKQVFGTIDRLKEFGPKYINITTHHSENIYKEE
EDGTIRKVNVRRRPGSVAIAAAIQNKYGIRAVPHIISQGFSREETEYALIDLSFLGVTDL
LLLRGDTKKLDADQRNVDSHPYATGLQEQVNNFNKGIAFDGSAFPVPETPFTYGMACYPE
KHEESPNMESEIHYTKMKAQNGADYLVTQMFFDNQKYFDFVDRCRAEGITIPIVPGIKPI
HLKNQLNVLPKIFRTEIPEDLERELRKCKTDADAVEVGVEWCLLQSKELARRGVPGIHFY
ALGATESIYRVAKEVY
>A0A0P1GWY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter sp. CECT 5382|TrEMBL
MTPKISFEFFPPQNLEASFRLWDTIQVLAPMDPRFVSVTYGAGGTTRDLTRDAVKTLHSS
SGLNVAAHLTCVNASKAETLEIAENFAAAGVSEIVALRGDPPKGEGSFTPHPEGFANSVE
LVEALAQTGKFTLRVGAYPDQHPEAATTQADVDWLKRKLDAGADEALTQFFFESETFFRF
RDACAAAGIDGDTLVPGILPIENWKGVRKFAQRCGTQVPTWLDDAFDKAIRDDREDLLAT
ALCTELCSELLDEGVNKLHFYTLNRPELTRDVCFALGITPKAALENVA
>A0A330LXF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moritella yayanosii|TrEMBL
MKYSIELVPRSWETLNTEAEEVSQFSQINTLNIPDLLRFDVRSWDACDRLQDKFDEVIPH
LRAIDFDLRNGFPLTDFFRHSKINSVLVVEGDPPQDISHRTYRNTSCELIRIIKKELPYM
KVYAAIDQYRTSMRKELDYIHDKLDAGVDGFFTQPFFDLKLLDVYMDMLQDTEVFWGLSP
IHSETSKSYWENKNDVVFPSDFEPTKEWNIKFGRAMIKKVQAKDDNVYFMPIRANVSEYL
NKLLAED
>A0A3D1JPD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MTAANAPSTGVPVSFEFFPPKTPEGAEKLRAVRQQLYALRPEFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREQLAQLRAMGVQRLVALRGDLPSGYGMGGEFHY
ASDLVAFIRAETGQDFHIEVAAYPEVHPQARSPEADLKAYVTKVQAGADAAITQYFYSAD
AYFRFVEDARRQGADVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDVASI
RAFGLDVVTGLCEQLLAAGVPALHFYTMNQSVATLEICRRLESSLGKRT
>G6ECD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium pentaromativorans US6-1|TrEMBL
MQPGDISVSFEFFPPKTEKMETQLWEAITQLAPLSPSFVSVTYGAGGSTRERTHATVSRI
IRETDLVPAAHLTCVAASKAQIDEIVDRYWEAGVRHIVALRGDPPPADGSIFVPHPEGYA
NAADLVAGIKARHEFDISVAAYPEIHPDAANAEADLDNLKRKLDAGASRAITQFFFSTDA
YFRFLDKALAAGITAPILPGIMPVTSFAAIRRMSGNTEIPAWLEAMFEGLDDRPGPRALV
AAVAAADLCKRLYDGGVRDFHFYTLNRAEQAYAICQLLGLRPKEIG
>A0A7C3HZ38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVADILNQSKKTQVSFEILPPLKGNSIESIYHALEPLMEFSPPYINVTYHREEVVY
>A0A848YA54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MTTLSHRAWTASQNTAPIEVSFEFFPPGGQKAFDRLMNTAESLEPYAPRFLSVTCGAGGT
DDLSNDKSFDAIQSLRRSVDTNLAAHLTCVGRSKREIDQRVREYAAAGIRRIVALRGDAP
EGQEYRPHPGGYANAAELVEGIRKITDLDISVAAYPEAHPDSPSRAADIFNLKQKLDAGA
N
>A0A5N7TVM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKVGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A7W1EIC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKLVQKLSQSKKPLFSIEILPPLKGKSIQSIYDAIDPLMEFKPAFVDVTYHREEYIYKKR
DGGYLEKVSIRKRPGTVGICAAIMNKYNVEAVPHIICGGFTREETENALIDLHFLGIDNV
LALRGDSIKTEPAFVPEPGGHAYAIDLVKQVREMNMGQYMDDDMKDAAPTDFCIGIAAYP
EKHFEAPNMISDLKYLKAKVDAGAEYIVTQMFFDNQKYFDFVDLCKKNGISVPIIPGLKI
LSSKKQITTLPKIFHIDIPQPFYEELEKCKDDKQIKEAGINWCIQQSKELVKANVPCLHF
YTMGASDATKRVAKEVF
>A0A7J5ENN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MIFNKQGSRPFITDGSMAVELAKRGFAERPPDRYNLSSPTVVERIYHEFIQAGATLLQTN
TLFSNRFALESVMLSARVAELNRKGVWLARTASAGRVPVLGVIGPTGRLLQPLGPLNATD
AEECFREQAASLLSAGCDAIALKSFIDITELEIAISAVRAVSTDVDVIALKSFPEDAAVL
SGPYPKLFAKRITRLGIQAFGSNGTVGPQRMVGIVDALVNDTIPLVAIPDVGIPTMIGGT
AVYHANPEYVGQAATRLAEHGASIVGADGGATVEHIAAIAQAVASASVGSKTPVVQVTEH
NAVPDSHPKPPTQWYTDLQSRFMRTVELDIPRGLDMSSVIEGARYLHANGIDAVNISDGA
RARLRMNPISISRLVMDAVGIQCITHMACRDRNMVGLQSDLLGAHELDVRNILAVTGDPT
HIGDFPYASSVYDVDSIGMIRAMDRMNHGNDLMGNPLGSATSFSIACAVNPAADDIEREV
DRLAQKAEQGAMATFSQPVFDDDALYTFLDRISHIPIKFIVGIIPLRNLRHAEFLHFEVP
GMHIPSWVRKHMLENNESQQQATSAGIHLAVQMLSAVKNKVHGVYLMPPFKKYSVAVEVL
QRAGL
>A0A846YS56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura latina|TrEMBL
MVTEGMGFEIVCEVEPPTRPDLRTVRHQIGVMSPVADSFLIPDNHIGRATVSSVAVAHEV
QAMGARGIACLNSRDRNLLGFRRDLLTAAAYGVDRFLFVYGDKPGVGGRTSELTVRAMME
EARAASGDEVFAGCAPFQVGVTSGLRRVPEWKRAADFTFVQVSYSVESLLRWREDAGIDG
PVYAGVMVLASAGMARNLAAAIPDIDIPAELVEAVERDRAAGVAAACEQVLAVRDTGAFD
GVHLVPVSRYREVAARLEGEL
>A0A7Y7NIK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MNITEILNNTNKTLFSFELLPPLKGTNIQLIFDTIDPLMEFTPQYINVTYHREEVVYKKH
PNGLLEPRVVRKRPGTVGIAAAVMNKYKTPVVPHIICAGFNKEETENGLIDLDFLGIDNV
LVLRGDADKSMGKFIQEPGGHAHAIDLLKQIMNMNNGKYIDSDIENSTPTNFICGVAGYP
EKHCEAPNMELDLEFLKAKIDAGAQYIVTQMFFDNKKYYSFVENCRRKGIDVPIVPGIKP
ISIKPHLSVLPHTFHIDLPQELTNEVMKCKTDAEVRAVGVEWSIKQCKDLLANNVPIIHF
YTMGKSDNIAKIAKEVY
>A0A6L5FDG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MQEQTSDASTTTLQSRLRGGQFVLTAEIAPPLSCVAGDLLAKALPLRGLADAVNVTDGAS
ARAHLGAVAAAALLIGAGIEPILQFTCRDRNRIALQSDLLGAAALGVRNLLLLTGDDPKA
GDQPDTKPVFDLNSQQLLATARDMRDRGELPSGRKISGALAFFLGAADLPVDPKPDWKPD
ALKKKIAAGAQFAQTQFCMDAGVVRRYTQRLREDGIEDFHVLIGVAPLRSAKSVRWMRKH
LFGTIIDEAIVARLEAADDPAAEGARICVDLIEELAGIPGVSGAHIMAPGQDGAVPDVLK
AARERLGR
>A0A352A004|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MSALHLESSSIRDWTVAGALVCDGSMALELAKRGFTERPCDRYNLTSGVIVERIHVDFID
AGARLLQTNTQSANRFALESSMLSARVHEINRKGAWLARSAAGSRAVVAGVVGPCGRLMR
PLGPVEPEDLRSSFHEQVSALLASSVDAIMLKSFIDLDELEIAIDVVRSQSLHIPLIALK
SFPEDGSVLAGSFPSDVAHRLRGHGVQAIGSNGTVGPQRMIGIIESLRVSDLPLVAIPDI
GIPTIIDGQPMYNAEPAYVAAAARRLVEHGAAIIGADGGADVAQVRAIAEAVAGAEIGSS
PVVTKRSAVHHEDEQAEAMPTSFMQSITQRRVVTVELDVPRGLDMSSVVEGARYLRDHGI
DAVNISDGARARLRMSPIAISKLVTEQTGMECISHLACRDRNMVALQSELIGAHEMGIRN
ILAVTGDPTHIGDFPSATSVYDVDSIGLVRAMGHMNHGKDLMGNPLGSRTGFCISCAVNP
AADDLGREIDRLAMKAEQGAHVAFSQPIFDVELLDRFLDRIKDIDIRFMLGIIPLRTIRH
AEFLHYEVPGMTIPSWVRERMRAATSTEEATDIGIEIAVSFLDAVLDRVSGIYLMPPFKK
YDIAVRILSNINLQR
>A0A7Y5SXH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MRISDILQKKGKTFSFEFFPPKTDAGVETLLRTVDRLKPLNPDFVSVTYGAGGSNRHRSF
GIVDTIRNQIGLEVMAHFTCVGHTTDELQDSLNELKSRNIDNILALRGDPPKGDSGWVPP
PNGYRYASELVRHIRMGGHFCIGVAGYPETHPEALSPEADIENLKRKVDEGGDFVITQLF
FNNDEYFRFVDRAARAGIHCRIIPGIMPITNFGQIKKFSEMCGAVIPPRLVEALTEVESD
PTEVALIGLEHAMIQCRELIAGGAPGLHFYTLNKSAATRIIFENL
>A0A522GCS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MSAINPARRWQPAFFPFRKEKWTRRVLAKTELFIKGPLFGCRMCGNCLLQETAFICPMEC
PKGMRNGPCGGITPEKRCYVDETRKCIWYTIYQRALKTRREEMLLEVLPPLDWEKVGTET
WGEVFRYIRKVGAGKFMGGILSNNKIKKAEIWDRVFKTIRQPDWWRGDSDYHPATTGEPV
SDLERRFRNGEFIIATEVTPPLSTKTEKFIKNIESVKPYVTAINFTDSSSVRPKMSSIAC
SKISIDLKAEPILQITARDTTRTGLQSTIIGANAMGIKNILCITGDNPRIGSAPVSSLNM
LDIDSVQMLWILRRMRDESIYLDGRKIKESPKLFLGAATSPFASDPVLQAIKDHKKVNAG
AQFFQTNLIFEPDRLDLWLEQLDKRNILNKVYILVGVAPLKSYKIAQYLHTKVPGVTLPE
KILKRMENAGESAPEEGVQIVLEMIDSIKNKQGINGFHIMTLSWESIVQRIVTESGLLEV
TKKTN
>A0A7V2W5P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTDYFENANGQTLVSFEVLPPLKGGSMAAIFDTLDPLMEFKPPFIDVTYHREDFVYKK
MPSGYYEKIAIRKRPGTVGICAAIMHRYGVDAVPHLICGGFSKEETENALIDLNFLNINN
VLALRGDARSFDGKFMPEPDGHEYALDLVKQVANMNEGKYLDDNIENGLKTNFCIGIAGY
PEKHFEAPNLATDLEFTKAKVDAGARYIVTQMFFDNKYYFDFVKECRKAGINVPIVPGLK
PLTKKYQTSSIPRHFYIDLPGDLSKEIMKAKNAEARTQVGIEWCTMQSKELKENGVPCLH
YYTMGDAATIRKIAEGVF
>A0A378Z6F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea pulmonicola|TrEMBL
MTQPSFSFEFFPPKTAEGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQGTLDTVVEIQR
EGVEAAPHLSCVGSTRENIRQILATYRQHGIRHIVALRGDLPSGMGEIGEFRYASELVEF
IRAETGDWFHIEVAAYPEYHPQAKSPRLDLEHFANKVKAGANAAITQYFFNADAYFRFVD
DASRLGVDVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTALCERLLADGAPGLHFYTLNAASATKAMWQRLGL
>A0A3M1MZK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
NLAFDLANLKRKQDAGASYAITQMFFDNQLYYTFVEKARALGIHIPLIPGLKILTRREHL
HSLPRSFHISLPEELTTAILEAKDDREVAEIGIEWAYRQATDLLSHGVRNLHFYTMLYTK
PLIRLMEKLKLD
>A0A167Z5C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moelleriella libera RCEF 2490|TrEMBL
MHIKDMLSEAEKDGQPSFSFEYFPPKTAQGVQNLYERIDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLDKVNDALQKAYKAGCTNILALRGDPPRAQER
WTATEDGFQYARDLVKHIRATYGDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGASF
IVTQMFYDADNFIRWVGKVRQRGITIPIIPGIMPIATYASFLRRAKHMQCRIPDGWMAAL
EPVKNDDVAVREIGMTLVAEMCRKLVASGIHHLHFYTMNLAQATRMVLEELDWAPCAERP
LQHALPWKQSKALGRRDEDVRPIFWRNRNRSYVLRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKRWGEPVTVKDIANIFVRYLKQEIDTLPWSEAPLTSEADAIKDKLIA
LNDRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPASIFTEMVKRIDSKP
VLTYYAVTKAGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGTDW
AHCFDLKTPSRTLLDKVMDEWYLVNVVNNDFHENETIFELFDGLEVSGLDAPTSA
>A0A2T4WVH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
IIPPKRGGSLKQIFDAIELLKPFHPPYIDVTSHSAQSYLEEQADGSFKRKIRRKRPGTIG
LCAAILNRFGIDPVPHILCNGFTKEETEDALIELNYLGIHNVMALRGDNQGEKKIDPLGR
DSNLFAADLVQQIQRMNKGIYLEKLENAEKTNFCVGVAGYPEKHIEAPNLSWDIKKLKEK
VDEGADYIVTQMFFDNEVYFHFVEKARAEGITIPIIPGLKVMTTYNQLKSLPEYFYLTIP
EALSDEVEARPERVREIGIEWTRKQCEELLTRGVPGLHFYVMTNPTAAIEVLNELPVKRV
QSRL
>A0A127N163|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas citronellolis|TrEMBL
MSQDRRFSFEFFPAKTEAGHEKLLATARQLAGYKPDFFSCTYGAGGSTRDRTLVTVLQLD
GEVNVPTAPHLSCVGDTKAELHALLAHYKDAGIRRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGDHFHIEVAAYPEVHPQARNSEHDLANFVRKVKAGADSAITQYFFNADSYFH
FVERAQKLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIASIQSFG
EQVITEMCERLLDGGAPGLHFYTLNQADPSLALWKNLKLPR
>B8KBD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 16|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDANREELIQIADDYWNNGIQSIVALRGD
IPPGGGKPEMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPSAS
>A0A0R2TI37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter sp. BACL10 MAG-120910-bin24|TrEMBL
MALFNFRLKSDAPIATPAAIEALLANYSIEVMPRTAEKVEDFRALLPQTTRVYVAHIDGT
PIEDMVATAKRLKDQGFTVMPHFPARIIKDKVMLEEWISRYQNEAGVRQALLLAGGVAQP
HGVFNSSMQLLESGAFGDFERVHIAGHPEGNRDIDPDGSDKMVMQALHWKQSFSKTTDAK
MAMATQFCFEADPVIAWTSRLAAEGIDLPIHIGVAGPAKLQTLIKFAIACGVGASLRVLQ
KRAMDVTKLLLPYEPNDFIAALAYHKAAHPNFGIEAVHFFPLGGIKPNAQWAIDNGGASG
AAALNS
>A0A2H0A7H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desantisbacteria bacterium CG23_combo_of_CG06-09_8_20_14_all_40_23|TrEMBL
MSKQFKDVLASGEFVITSEIGPPKGTNIEKMLHHIEILKDKVHGMNVTDNQSSVMRLSSV
AVCHIITDHGGEPILQMTCRDRNRMALQSDLLSAYVLGVRNVLCLTGDHISLGDHKGAKQ
VFDLDSVQLIAAVKSLEAGQDIGGNKLDGGVEFCVGATATPEADNMDSQFLKFRKKIKTG
AGFFQTQAVYDMVKLKAFMEYARQSDVKILAGILVLVSAGMARYLNANVAGVTVPQELID
EMAGAEKGKALQKGMEIAARQIKQIKDEKICDGVHIMAIGKEEVVPEILSMSGV
>A0A166TAW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium coskatii|TrEMBL
MSLLKEAFEKGEFAITAEMAPPKGTDLSHLIECAKKIKGRVQGVNVTDFQSATLKATSLA
TCKVLKDAGLEPVFQITGRDRNRIAIQGELLSAGVFGIENVLALTGDYTATGDHPGAKPV
YDLDSVGILQVASILNGGKDMGGTDLKGKPDFFLGACVTPRYDPLELQVIKMKKKIKAGA
KFFQTQAVYDMETLKKFKEETKAQGVDAKVMVGIIPLKSAGMAKYMNKNVPGIFVPDELI
DRMKNAEDKVQEGIKIAGEFIKAVKESGLCDGVHIMAIGAEENVPLILDEAGL
>A0A5N6EQ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus novoparasiticus|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNRDFTFAVDLVRYIRQKHGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYL
VEKTQAGADFIMTQLTYDIEAYTRFENMLRTHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVQIPPQILSKLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLRGFHFYTLNLEKT
VSFILERCDLIPPYSEDFDAIEEGGDISAMDGAQLRSLTRRRASSINSLPHNRVIVDKLH
ASEVSSKASVSHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSS
GLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFF
CPSKDYHSILKPLLQKHGHEKLAWFAANIKGDFESSLPAQTSDADPIEMNPNNVNCVTWG
VFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNDVKDDVWLVCVVG
QEFGAGTEMGSKEEEDEKKFMWRVLLNAKK
>A0A180FJ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium Barb4|TrEMBL
MKVIDLISSGKQPAFSFEILPPLKGNTIKNVYSVIDKLYEFAPRYINITSHHSEHQYKTL
PDGSFQKVSIRKRPGSVAIASAIQNKYHIPAIPHIICKGFTKEETEYAMIDLNFLGVHDL
LLLRGDNKSQETQPSPDLYHSHATDLQQQVNNFNRGIALDGSAFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNAKYYAFVERCRAEGITVPIIPGIKPV
VFKSQLTVLPRIFRSDIPEPFAAELRKCKDDEAAKAAGIEWCVSQCKDLAAHGVPGLHFY
TFMASDSVYKVAKEVY
>A0A3M1PCD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVIELLDRATEPLISYEIIPPERGGSVAQIMAIIEDLMAFDPPFIDVTSHSAQVYYEEM
PDGTWRRHVKRKRPGTLGLCAAIKGRFGVETVPHLLCYGFTREETEDALIELNYLGIHNV
MALRGDANGYEKPILFNRTRNEYAVDLVRQIAEMNRGQYLEELIDAAPTDFCIGVAGYPE
KHFEAPNLMWDILNLKRKIDAGAHYVTTQMFFDNRHYFRFVERCREVGIEVPILPGLKII
TSKRQLRMLPSRFHVEVPEALAAEVEAARDEHVPDIGVEWALRQSQELMEAGVPCLHFYI
MQTADHVRRVVHALRKMA
>A0A420WVT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kushneria sinocarnis|TrEMBL
MTHNAFHTSFEFFPPRTDAGRDKLMGVRDRLVERDPSFFSVTFGAGGSTREPTFDTVRQI
REAGINTAPHLSCVASDKASLSHLLGRYREAGISRIVALRGDMPSGTMAAGELRHARDLV
DFIRHETGDHFSLSVAAYPECHPQAPSFERDLDHFADKVHAGADMAITQYFFNAEAYFHF
VDQVRQRGVDVPIVPGVMPITNFTKLARFSDMCGADIPRWIRRQLEAYGDDSASIRAFGE
EVVSRLCQQLIEGGAPGLHFYTLNQADASLAILDNLGLRSH
>A0A2V2B001|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CG 926|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMADWVAHPDGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVEKAGCDTPIIPEVMPVVGIKQLDRLPQLSTAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A420TPH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella intermedia|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A4Y1WRC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes communis|TrEMBL
MNVLDIIRETSARETTRFSFELLPPLKGDGTRSVFTTIEALREFDPAFINVTFHRESIKE
TLTPDGHIEWHRMRRRPGTVGISAAIRDRFGIEVVPHLICGGLSRYDIEDALIDMDFLGL
HNVLALRGDCGPNERHFMPHPQGHSHAIDLVRQIAAMNRGEFVDGEVEECHHSKFSIGVA
GYPEKHVDALDAESDLRHLKAKVDAGADYVMTQICYDADRILAFIGRCREAGIDVPVIPG
VKPLSTLRQLTLLPETFAIELPEALYSEVRAHADRPEAIRRIGVEWAVDQCRRLKAAGVP
VIHFYTMGRAENVRQIIKEVF
>A0A510L7L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia hongkongensis|TrEMBL
MKIKDMFEQKKHLVSFEIFPPNKNFSHDKLKEVTAELVEYKPDFISVTYGAGGQTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKNEIHDYLQEAKSKNVKNILALRGDVPQGETEDIYN
KGDYKYASELISDLRKNSEFDDFSIGGAFYPETHYENNDLIDLFI
>A0A427Y0P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apiotrichum porosum|TrEMBL
MPHITDLIARDDRPFHTFEFFPPRTEPGVANLLDRVARLAASPLRAPLAVSVTWGAGGST
ADRSLELAENIARMGIDVILHMTCTNMPKAKVDAALKRARAIGISNILALRGDAPRGEEY
ALHASDHADEFQHADDLVRHVRKEHGDYFCIGVAGYPTPHPDSENADSDIKWLKAKCDAG
ADFIVTQLFYDVPSFVEWVARCRAAGISQPIIPGVMPIQNYVSFRRLVNLTKCPVPEGIM
RDLEPIKGDDAAVKLYGAKVATELVQGLIASKVVRGVHFCTLNLEKSVRTILENLEWTAA
VPVPIRGSPHTRHNQLIADDGVPAPSGADSLSISPSDASVLAQWGLNRAHQTAPQASPAK
PPLPTAGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITPAQALKEWGTPATPADLSSL
FTRYLHCDPAAPTTPFCDMPLSPESETILPFLIELNSAERQYWTVGSQPAVDAARSEDAV
HGWGPPGGYVFQKAYAEFFVPLAQVQKLERKLVSENPNGRISMYAANRRGDYLTNTLKDA
VNAVTWAAFPGQEIVQSTIIEEISFLAWKEEAFDIWREWSLLYPRASPARKLLEDVSENW
WLVSVIHHDYKDAKGLWRFLLDE
>A0A2M8A9I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium CG_4_9_14_3_um_filter_32_8|TrEMBL
MKITEHLSKAKKVLFSLEILPPLKGNGIQSIYDSIDPLIAFGPSFINVTYHREEFVYKKR
EKGYLEKIAIKKRPGTVGICAAIVNKYKIDAVPHIICGGFTKEETENALIDLNFLGIDNV
LLLRGDPIKTEASFIPEEEGHHYAVDLVRQVVGLNQGIYMDEDLQNAQPTNFCIGVAGYP
EKHFEAPNLKNDLKYLKQKIDAGAEYIVTQLFYDNQKFKTFVNLCREEEITVPIIPGIKP
ISSKNQILTLPKNFHIDMPHELVEAIEKCKSDEEVKKVGIDWAIQQSKDLIEFGVPCIHY
YTMGKSLSVREVVKAVF
>A0A511XDS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter nitrogenifigens DSM 23921 = LMG 23498|TrEMBL
MPDASPIASALTNQRRVSVELIPRDEASLRNDADEALALAPQADTINIPDLMRFDLRSWK
AVSLVRDRVSAAIPHIRAIDVDPDKPLPGTDDPAIREVLVIRGDPPADLNRRTFPNSSES
IIRRYQREAPEIAVYAAFDPYRQAPYQELDAVQRKRDAGARGFFTQPIFDMRMLDLCREW
LSGETVFWGLSPVIGPRSRSYWETTNRVIFPRNFEPTLDANIAFADAAIRAVRSDGGSVY
LMPLRVKLANYLTPLTAALSS
>A0A4V0X4P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVIDHIQQAKDTLVSFEVLPPLKGKNIASLYQHLDPLMEFKPSFINVTYHRSEHIFKKK
QDGTFEKVEVRKRPGTVGICAAIMNHYQIDAVPHLICGGFTKRETEDALIDLNFLGIDNV
LVLRGDATKNESSFEPEPNGNKYAIDLLQQVDRLNNGIYLEEDIREGFRTNFCMGVAGYP
EKHFEAPNMDTDMRYLKAKVAAGAEYIVTQMFFDNAKYFEFVDKCRANDIHIPIIPGLKP
LTSKKQLTVIPRIFHVDLPTDLINDMHKSKTDAESEQVGMNWLVHQSKELKKAGVPVLHY
YTLGKPMLIRDAVAQVF
>A0A8J2HKR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cotesia congregata|TrEMBL
MPKNTLLHMTARGKTKSDVKKILNKALELGICNIFAIRGDNECTTGDFLYAVDLVKFIKK
NYNDKFSIAVAGYPDRHPESVNKESEFFYLKKKVDAGADFIITQIIFDSKAFINFVKDCT
ENGISVPILAGVMPVINYSSLMKTINVCGLKIPETVHKHLEKIKEDDLSVHQYGVKLIIE
IITDIMDHGFYGFHFFTFNKSKTLLEIFNYYLNK
>A0A0A2U0E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. MAEPY2|TrEMBL
MKADLRSVMRERVLIGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
HETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGANGFVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGASPEYFGQTAVQFADLGARIIGGCCGTTPDHISAIAKALVEYTPVPILEPDPSE
SKPRIILHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVSFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
SMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A1F9DC24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_54_18|TrEMBL
MKSGSNLEKILGKGEFAVTGELGPPKGNAAEVIKKKAEHLRGKVDAVNVTDNQTSIVRMS
SIATSAILIQMGLEPVMQMVTRDRNRIAIQSDIFGATALGIKNMLCLSGDHQNFGNQKDA
ANVFDIDSIQLIQCVKTMRDEGTLLGGEEKVEGEIKLFIGAAANPFADPFEFRVVRLAKK
ARAGVDFIQTQCIYDMDRFKEWMRMVRDRGLHEKVHILAGVTPLKSGGMARYMAKNVAGI
IIPDAIIERMVKAKEPAQEGIKICVEQIHQLREIEGVHGIHLMAIEWEEKVREIAEGAGL
LPRPKV
>A0A2E2Q779|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp|TrEMBL
MTTDLLPLIEECPKRMRFGPCGGVGLAGDCEIDRAARCLFIERTAPAVEPSGATRRPTHR
GRLAGLLAAGRFAVIGEVNGADTADVADFVAAARSLSGVVDVVSVTDHSGANVRMGNVAV
SAHLTAAGIETMTTFSCRDRNRMALQGDLLGVASLGVHNVLCVTGNHVAVGDSPDAAPVF
DLDSSRLIAAAAQLRDQGVLLNGRALETRPSYLIGGAAHPFAPPYADRPAQVLRKAALGA
DFLITQHIFDLPRWRAFLADLDALRAAAPPFALLGGVAVLPSEPIARRVNAGLRGFTIPG
EVLRRLRQARDPQAEGIAIAAETVAELAAAPGVGGTLIAPVTGRTNALAASVEQTEIIAS
VLAAAGVTPPTGEEATSWAS
>A0A2E2Q0C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp|TrEMBL
MGSVTGVTTAATACPKGMTFGPCGGVREDLRCELADHRCTFADLAGPVPWTAREAAPGPS
SSVLLAALDRGDAVLSDLTLPSYDPAAVAESVAVMRGACDALLLGEHQNRPDFPPTVLAA
LVREAGGVPWVTLACRDRNRVVLEQEVAGLGLVGADGVLCVTGDGRAPGVRPGVTQVFDL
DGTRLAALAAGRGLAVGVPESPEAAPRQLRPGRLVEKQRAGAQVAVLNHAGSPETVARFV
ARARELGLTIPVVAGVAVYTDAAGARVLQGFPGLHLDDARVEQVLVAGDVREAGIEAAVE
EARSLLAVPGVSGVNLSGRGSSSSELDGAEVKAEIGRRIQEGA
>A0A2E5C820|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccus sp|TrEMBL
MNDRHLSFEFFPPKTPEGREKLRFVHSQLARFNPEFFSVTYGAGGSTRDHTRDIVLEINR
AGSNATPHLSFGGDSKQSVLSLLETYREAGIRRIVALRGDLPSGMGGSTQLVYANELVQF
IREHFGDTFELLVAAYPEIHPEAESYKKDIYWLGQKFLAGASRGITQYFYNIDAYFYFRD
QCLAAGIQSPIIPGIMPITNYQNLIRFSDNCGADVPRWIRQQLKSYGTDAASIRAFGLDV
VSRLCEKLLAEGAPGLHFYTMNQADTCTTLCRNLGFPITDA
>A0A1I3G0C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium NLAE-zl-G231|TrEMBL
MIKDLFAEKKQLLSFEVFPPKKEDEFANAFAVLDSLAGLQPDFISVTYGAGGSKSKKTVE
IASYIQNQLHIMALAHMTCVGSKKEDIDAVTAQLKEVHVNHVLALRGDRPSYMSDEQFDS
RHFSHAADLITYLKGETDLHIAGACYPEKHYEAADLESDLLHLKEKCDAGAEFLITQLFF
DNEAFYKFLEKSRNAGITLPVCAGIMPITSAKQLGTTVSLSGSAVPKQLADIIATYGDDP
ADMRKAGIDYAIRQILDLKAHHADGIHIYTMNKPKVAQEIVSAIQ
>A0A2G9LNH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeum sp. CG12_big_fil_rev_8_21_14_0_65_33_22|TrEMBL
MYKITDIFKRKKKTFSFEFFPPKTEEGMKHLFETCDELKKYPDFFSVTYNPDGSSRERTL
FVVNEIQKKFKIPVMHHLTCINYNERTL
>A0A7C4Q9C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRRGVMPGFTPGRRWQPAYLPFHDEPFIDRVVETLELTIKGPLFGCRMCGNCLLQETAFI
CPMECPKGLRNGPCGGSTPEHCYVDTTRPCIWYKIYERAEKLGREEKLLEVLPPLDWEKV
GTDSWMDVYRHWRKKGGLKFTWDLLTAPPAQRAKAWEQFFYEIRQPEWWGGDDQPHPAPP
HEPVSELERKLTAGEFVVTAEIAPPLAAAPDEVVKKLNLLRGYIDAANFTDNPSATPRMS
SLVCSAIAVQQGLEPVMQIAARERTRMGAQSTILGAAALGIRNVLCLTGDHPRVGPSPHG
RMDIWDLDSIQMIWMFRRMRDEGRFLDTRELKNAPPLFIGAAGSPFAANERIQALREQKK
VNAGAQFFQTNLVYDVEGFERWLAALDKRGVLGRVFILAGLMPIRSPKAAQAIAAVPGVK
MPAALLERMAQAADPKEEGVQITLEIVDRVKRLPGVNGVHFMSVGWESIVPRLVKEAGLL
KPAPVQAPAAG
>A0A7V4H0I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
TLTRQVGGFSIGVAGFPEGHLECREGRHVDWERLKAKIDCGADFVLTQLFFDNAFFYEMR
DYLIGRLGVRVPIVPGIIPIQSTAQIRRFVALCGATIPSGLARRLDELGDNDTATAEFGV
EYATAQCADLLRQGVPGLHFYSLNKAAPVTRILADLGLAGPGEGA
>A0A381K0H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens|TrEMBL
MRVDEVFKQAASQGTAPISFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GAATAPIAHMITSEFDTPSVAHLTCVGRSHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A7C3RET2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
EFFPPKTAEGERILFDQTIPALKQTKPAFCSVTYGAGGSTRDKTLMIVERLLHEHGLVVL
AHLTCVNHTQTEIAELLDRIAALGCRNILALRGDPPEGGEFRKTPGGFEFAFELVQFIRQ
RGDFSIGVAGFPEGHIACQAGKYTDWHHLKHKIECGADFVLTQLFFDNADFFEFRDCMTG
KLDVHVPIVPGIIPILSASQIERFTELCGARIPAALAAKLDQFGTDTAATTEFGIEYATR
QCDELLRAGVPGIHFYTLNRSYSTVRVLKHLGLA
>A0A7C1V4Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKSGTNLEKVLAEGYFAVTGELGPPKGTSADFVRRKAEILRNYVDAVNVTDNQTAVVRMS
SVAACAIIKQMGLDPVMQMTCRDRNRIAIQADILGAVALGIGNLLCLSGDHQKFGNHPES
KNVHDIDSMQLIQIVRHMRDDARFLSGDKVSGGVEMFIGAAANPFADPFDFRPIRLEKKV
RAGADFIQTQGVFDVDRFIRYMELVRERGLHERVHILAGVIPMKSAGMARYMRDYVAGLS
VPDELVERMENAEDAKEEGVRITLEIIEQLREIEGVHGIHLMAVAWEDIVPVIVERAGLY
PRPIV
>A0A7C1JK16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPAIPFRQRLESPAPILADGAMGTMLHANGSLPIDSCFDFFNISRPDVVLDIHRAYLKSG
AELIETNTFSANRHKLAEFGLEDRLAEINHAGVALARQAIAESGRENVYVAGSIGPLGTG
LQPYGRMKPEDARAFMHDQIAALAGANVDAFIFETFNDLAELLLGIEIAREIAPHIPTIC
QMTFGPDDRTLIGYMPARVARDLHAAGADVIGVNCSGGPAQISRVIQAMMHAVPDARYSA
MPNAGFPQSIGGRMMYPATVEYFADFAASLKALGATIIGGCCGTTPRHIAAMRAAVDDPN
RKTTVFRISLPRKTDTQPDGIDPADDTAQTDLGNTPPQGTFRPSELARKLAARDFVVTVE
MAPPRSHNLDRLIDNARLLLNAGATTLNIADSPTARMRVSAWAVCHMLENRLGIETILHF
PTRGRNLLRIQGDLLGAHALGLRNLFVVMGDPTRIGDYPDANDNFDIAPSGLIKLTKQKM
NAGVDQAGNSIGQPTSFTVGCALNMGADDIDKEIEVLRKKIESGADFALGQAVFDPRQAE
AFLKRYEEVEGHALELPILMGVMPLNSLKHALYLHNEVPGITIPDAILKRIEGAGEDAAR
EGVVIAQELLRDMRGMIQGAYIIPAYGKYDNAALVIDSITAKA
>A0A7C6TSW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKSGSRLEAILSSGTFAVTAELGPPKGPDVEVVAKKMGLLRDTCDAINVTDNQTAIVRLS
SAATCALLCRDGLEPVMQMTCRDRNRLAIQSDLFGAVALGVRNLLCLSGDHQVFGNHPTA
KNVFDLDSVQLVQMVARMRDQGLTAGGDPVEGAMPLFIGAAANPFGDPFEMRIIRLVKKV
AAGADFIQTQCIFDIPRFREYMKRVVDMGLHEKVHILAGVMPLKSAGAARFINSNVPGIS
MPDEIVRRMSGAGRGNKARAEGIALCAEMIQELAEIEGVHGVHIMAVEWEEAVQPIVERA
GLLPRPTMADLSGAEE
>A0A3M1YT02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSKLPFLERIHQTDRPLLGDGAMGTVLHARGNVAINTCFDALNITQPELVQSIHADYIAA
GAELIETNTFGANRYKLAEHKLQDKVAEICRAGVELARHAIAQSGREDVYIAGSVGPLGQ
RLKPYGRITTEEARQAFAEQIGALAEAGVDVILLETFADHTEALEALYAAREVAPNVPVI
VHTTFSADDRTLLGYAPARVANDLYRAGADVIGVNCSGGPSQISQILQTIRQAVPDAFIS
AMPNAGFPESVGGRVMFPATADYFGDYALTFKALGACVIGGCCGSTPEHIAAMRAALDDP
KRPLPIIQVLDSNGKDEDYVPAPPTSLSQRLARGEFTVTVEVAPPRSYDVETLVQRARLL
RDAGADILNVADSPTARMRMSPWAVCHIIQSQVGIETVLHFPTRGRNLLRIQGDLLAAHA
LDLRNLFVVMGDPTRIGDYPDAMDSYDIAPSRLIGLIKHEMNEGVDLAGNSIGKPTSFTV
GCALNMGADDLDREIRILLKKLENGADFALGQAVYEPSRVERFHEAYRATTGEDFTLPVL
MGAIPLYSLKHARFLHNEVPGIIIPDSIFKRLEDAGDDAPQEGVRIAQELLAEMNGLIQG
AYIIPAYGRYDLAAQVVDA
>A0A8D3X728|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Portiera aleyrodidarum TV|TrEMBL
MNNNELEISVEVFPPNENDKIKELISLIKMLYKKINITFCSITFGAGGSNKKNTLDVIKM
IKQNNIECVPHLSCISNNKPEIIKLINIYKKVGIKKILALRGDINKTYKKNHFINSLDLI
KLINKNFYKNFEIIVSAYPEMHPNTINFEKEVFFIIKKFCLGAHKAITQYFYDPDAYFYF
LEKVSKYGVDQPIIPGIMPIINLQKLINFSNKCGANIPKWIYKQLEACKNKNEIEIIGKE
IVIKLCEILIKGGAPGLHFYTLNKIEPTLNILNELIT
>A0A521TWD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVVGVEPGEVAASSAQTARPGSLRAHLVEPTTFVRIVELVTTRGPLAAANAARVVALGTD
LARMGTVHALSITDNAGGHPGLAPESLGARLRAQGQEVMVHLSCKDLNRNGLESRAWALA
AAGFENVLCLSGDYPGSGYRGQGAPVFDFDAIALLELLREMNRGLRTAASTLPPTSFFLG
AAVSPFKRYERELMPQYFKLARKIAAGAAFAISQIGFDARKFDELRRYTTLMGLDVPLIA
NVCRLSVPMARYFHRGAVPGVVVTDELLALVERQAASPDKGKRFFHELAARQVAIARGLG
YRGAYLGGHLKPDEVETIFAMADAFGRDDWRSFAGEIQFAQPGEFYYFAPDDATGLNSNE
INRDYLADRTPEARRARRARAPLAYRLNRSVHDRVFAEGSVGFRLGRRLYERIDNAPSAR
RWLHVAEQAVKIPLFGCRDCGDCSLPEIAYLCPESQCPKNQRNGPCGGSHAGLCEVSDRE
CIWARAYERLKAYGEAETMLDRPIVVRNGGLRGTSAWANCFLGRDHQSKRENS
>A0A6L3EZ74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTDVTHQNGYLAGSNLERVLRAGHFAVTGELGPPQSADGEVIRKKTTLLKGYCDAVNITD
NQTAIVRMSSIGAGTIVVQEGLEPVIQMTCRDRNRLAIQADLLGAYALGMRNLLCLTGDH
QNFGNHPNAKNVFDMDSLQLVHMVADIRDEHIFQCGDKFKGQEARFFVGAAAAPFADPID
FRPYRLAKKVKAGANFIQTQLVYDVPAFEKYMAKVRELGLHKQTYILAGVGPLKSPGMAR
YMKNKVPGILVPDELIKRMAAASKPWAGKKKDELTREDKIARSKAWKAEGIQICVELVQQ
LREIEGVAGVHVMAIEWEEAMKPIVEGAGLYPRPVVAEAVA
>A0A7C4N9Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPLFTPARRWQPAYYSFKREKASRRALAATERVIKGALFGCRMCGNCLLQETAFICSMEC
PKGARNGPCGGSTSERCYVDPTRPCIWYKIYERSFKLGREEKLLEVLPPLDWDKVGTETW
GDVWEQVQKVGVRKFFGGLLSKETRHDAWESVFEPVRQPDWWQGDAKYHPPAYTEPISNL
EKHLKEGRFVVTAEVAPPLTTATKKLCTNVNLIKPYVSAINFTDSPSATARMSSWACSVL
ALQNGAEPVMQIAARDRTRVGLQSEVLGATALGVKNILCLSGDNARMGPSPMSRLDVIDI
DSIQMLWILRRMRDEGKYLDGRDIKFAPKMFLGAAASPFASEPRFQAIREHKKVNAGAQF
FQTNLVFDADRLDIWLNELAKRNILDKVYILIGITPLKTFKMAKYMNDTVPGVFVPDSIL
KRMEAAGDRAEEEGVQIALELIEKIKTKQGVHGIHLMAVGWEEIVPRIIREAGLLPPDFV
EPEPVKEKKPKLEPVAAPVVSAN
>A0A536J0Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVRPLGAQSVGQALAAFLRTPRYEIFPTDDVLERVATNVPPEVTITVTASPRRGMPTTIR
LAVSLAQLGYRVVPHLSARLIRDHVEVGQIIEALQAAGIRNVFVVAGDAREPAGLFPDSV
SLLSALPPDHGLTEIGVTGYPESHPFIHDDVTIQAMWDKRRLATYIVSNMSFDPDGVKRW
VDRVRRRGVDLPIHIGMAGVADPAKLLRLSTKIGVADAARFLRGHPSWVARMFRPGGYDP
GRFTGALMPELAQPERRIAGLHVFTFNEIEPTERWRREMLARLS
>A0A661WSW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLPQNKPACSRLEETLRAGHFAVTAELNPPDSADPNDVYKAAEVLSGVCDGINAVDASGA
NTHISSVGICALLTRVGYEPVYQVTCRDRNRIAIQGDLLGAAAMGVQNVLCLSGDDVTVG
DQPEAKRVFDLDSIQLIRTVRMMRDESVLLSGRKLTTPPCFFIGAAANPFIPPLDWRPQR
LAKKIAAGAQFIQTQYCFDIPRFKEYMNQVRDQGLDKQAFILAGVGPLKSAGAANYMRTK
VPGVHIPDEIVERMKKTPKKKQQEEGKKICLDMIEQIREIEGVAGIHIMAYRQEELVAEI
VEEAGLLPRPIANVRLDQPAFCINA
>A0A2E6XAJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAFEATGKTSFICDFSPPRSGDPQIVDQAQIDVDLISVAYNPGRAVRTNSAMLAAAIKRS
GKESVFTLSTRDMNKLAVQSQLLGAQMLGVQNVIVVQGDPFNEKDRTMVSPVNDYRPTGL
ISAIAELNAGRDFRGGQLRSPTDFCIGATIDLRRGIEEEAQLAVRKVQAGAEFLITQPIF
NVDVVARYRESYGYHAGKAGTFPIYFGLQILEKDGVLFSSVPDSVREELEGGRSGVDIAL
DLYQKFQEARFNNIYLMPPIKRGGARNYEAAKEFLKKARNL
>A0A535C5A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIAERLKRREPVFSFEFFPPKTPEAVERLYDTARRLKALQPTFVSVTYGAGGSTRQMTV
DLVTRMKRELGLETMAHLTCVGHTKEQLAEVLDELAAGGIENVLSLRGDPPKGQTHFVRP
AGGFGYAQELTRFIKGRYAFCVAGAAYPETHTEAPDAETDLRHLKEKVESGAEFLITQLF
FEPELYFRFVERARATGIDVPIIPGIMPVTNVAQIHRFTSMCGATIPSSLRDLLDRAKDD
EAAVIAVGVEWGRDQARRLLEGGAPGIHFYTLNRSHSSQMILDALRGD
>A0A435C0S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.09.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A661WJM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNIAEILAKPGIHFSFEFFPPKTEKSSGVLLQSIKELTPLQPSYVSVTYGAGGSTRDLTH
DLLRSVRRETNLTVVAHLTTIGATRAEIREILHGYADAGIDNVMALRGDPPKGSPGFVQP
KNGFRYAAELVAFIKKEFPQMGIGVAGFPEGHPETPNRLKEMDYLKAKVDAGADYICTQL
FFKNGDFYDFRERCALAGIKVPITAGIMPITTRKGMERISELALGARIPAKLQRAILRTH
NDDAVAKVGIHWATQQVFDLFDRGVRGIHFYTLNKSKPTLKIYDALGVSPEDKPR
>A0A2E8R9E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNIVESNFKNKLTNNEFVITMEVSPPDEFDLQSFFPKFDFLSKTTIDALNITDTARAQGR
MSPLAISSLIQNQFDIETIMHIAVRHRNLLSLHSDLMGAHALGIKNIFSVMGDKPKKDSP
FFNSTFSNLTPNSALKLMDNFNKGISISGEKLKSSANFYKGAAFNPSTQNLEKEIQNLKH
KVESGADFLLTQPFYSTKTLQNILNIIGEFPIPLIIGVLPLRSIKNAQFLQTHVPGININ
SEIMSLMESSKSPIKTGMEISSNIVNQFKGKIAGMYYIPPFNNYKSILEFTKRLELPFSF
Q
>A0A2N6K9B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fischerella muscicola CCMEE 5323|TrEMBL
MLIFMLDTQNPTSLTSFRTAAKAGQFLITAEVAPPKGGNPEHMLKMAATLKGRVHAVNIT
DGSRAVLRMCPVVASAILLQHGIEPICQIACRDRNRIGLQADLMGAHAIGIRNILALTGD
PVKAGDHTDCKGVFDLESVRLLQVIQKLNHGVDYNDTPLNDGALDLFPGAAVDPQCPSWS
GLQKRFERKLEAGAQFFQSQLITDFEILEKFMDKIAVGCGKPILAGIFLFKSAKNAQFIN
RCVPGVNIPQHIIDRLAQAKDPLEEGMKIAAEQVQIAQQLCQGVHMMAVKREDLIPQILE
MAGVAPVNQMVSV
>A0A172Z8V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas antarctica|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYQQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A535XR32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MDRITDLLAAGRTFSFEFFPPKNDDEQRLLSRTIADLQPLNPSFVSVTYRGGRISRERTT
RVVVDLIKNTALTPMAHLTCVAHPRFELGEILGGFRAVGVENLLALGGDPLPAEESYKEL
EYASELVELGRRTGFGSIGVAAHPAGHPRSPDLVSDRDRLASKLELADFAITQFFFKLEE
YERLREDLAARRVTKPVLAGIMPITSLTSVLHMAQLSGYAVPDDIVKRITAGGDDPQEIR
KRGIDVAVELCSDLLTAGVPGLHFYTLNFSKATREIYTRLRLVPD
>A0A508WU19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium medicae|TrEMBL
MSPDINPYDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPHDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLSTPPHVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PLASAKTARWIRSNVPGIHIPDSIIRRLEGAQDQKKEGKQLCIDVMNEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLRGRKPWKREAAPTDAMVAERLEHIREGREENQQQMAEAAAH
HPHETKQ
>A0A2D6GBI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIRQILESKRTLSFEFFPPADDAGVKRLFNTIYALKAYDPDFVSITYGAGGSTQAVTVE
MAVRAQREIGLTVMAHITCAAQTAEFVDSALSRLATEGIENLIALRGDPPKGKSKFTAVE
GGYTHASDLISHVKRKFQFGVAAAGYPEGHPESIDLESDMKFTRLKIDLGAEFLITQLFY
DNDDYYAFVDRAQKAGVNVPIIPGLMPVLSASQIRRITGMCGASIPKELDELLDRHGDDN
RAVRQIGIEHTTRQASDLLDSGVPGVHFYVLNRRFSMTRILENLRESGHTTAFS
>A0A536JUU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARITDLLAAGRTVSFEFFPPKDSEEQKLLTRTIADLQPLHPSFVSVTYRGGRISRERTT
RVVIDLLNTTDLTPMPHLTCVAHPRFELGEIIGGFRAAGLENLLALGGDPLPAEESYKEL
EYASQLVELGRRLGFESIGVAAHPAGHPRSPDLVSDRKHLAFKMNLADFAITQFFFKLEE
YERLRDEMAALGITKPILAGIMPITSLVSVQRMAQLSGYAVPDDVVRRIQAGGDDRDEIR
RRGIEVATELCRDLLAAGVPGLHFYTLNFSKATREIHTNLGLVKD
>A0A535Y939|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQAVLQRGRFAVTAEIGPPRGANIAPIRRKARLLREWVDAANVTDSQSAVVRMPSWAGCL
VAMQEGVEPVMQLQCRDRNRIALQSDLLGAAALEIPNVLLLTGDHPRFGDHPDAKPVFDL
DSIQLIWTARTMREQRKLLSGRNLKPAPDWFIGAVENPFAPPLKWRAERLGKKIAAGAQF
CQTQFIFDVAIFASWMEQVRELGLEKRCFILAGVGPIRSLRALEHMRREVPGMHVPEEVV
RRLHGVPEDRVAAEGLAVCSEILAQVKEIPGVAGVHVMAFNWEDAIPEILERAGVGRRQS
WVAPPVRST
>A0A536JL15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADLLARSRPSISFEFMAPRDESEVDVLERTVAALAGHAPDWVSVTYRVRTGEKTLEL
VTRIKRHYHIEAMAHLTCANTADRTRQILNWMEREGVANVLALRGDPPTTGEPFTPADPQ
LTHASDLIRLVRGSGYRFGIGAACSTEKHPESPDVEHEFRYLQLKVESGADFLITQLFFD
NRFYFDLVARARAAGIKVPIVPGLMPVPSRRSLALMTTMSGASVPAALQAAIDEASDDDA
IRALGVRHCIAQCAELLEAGVPGLHFYTFNRARAPIAILAALRGQQLIAS
>A0A497CF27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSNENNNGYLVGTTLERMLKAGHFAVTGELGPPQSADGNVIREKAALLKGYVDGVNLTD
NQTAIVRISSIAAGAILIQEGLEPIIQMTCRDRNRLAIQADLLGAYALGIRNLLCLTGDH
QIFGNHPTAKHVFDMDSIQLVQMVTKMRDQKVFQCGEEFKGQEPRFLVGAASAPLADPLG
FRPYRLAKKIKAGANFIQTQLVYDIEAFAKFMEKIREMGLHEKTSILVGVGPLKSPGMAR
YMKNNVPGIDVPDEIIKRMSAAGKGEPWFGKKNADMTKEEKRARSKARQAEGIQVCIDLI
KQLREIEGVAGVHIMAIEWEKAVKPIVEGAGLYPRPSV
>A0A087QL32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aptenodytes forsteri|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7X3D1Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zobellia amurskyensis|TrEMBL
MKITDHIKNAKDKTLFSFEIIPPVKGHQIQQLYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYNVDTVPHVLCGGFTREETEYLLVDCHYLGIDNI
MALRGDAMKDEKYFQPTKGGHTYAVDLVKQVHELNCGNYLHETVDSDNCANFCIGVAGYP
EKHLEAPSLQSDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVEAAKKMGITIPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVDDCKSNKDVRKVGVEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAEQIF
>A0A3A6MLK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp|TrEMBL
MLHFLNFCNPVYICSMATQNNFSRSLFNTEEFTFTFELVPGQGSGGRRVDRLLDFARQAH
ADGRIKALSITDNPGGHPALAPHAIGSEVRSIGIQPLLHFSLKDKNRNQIESHLFFYHRK
GFSNLLILGGDFPRPGYYGQAKPVFDLDSVQTLCLMRDMEEGTYHSRAPHRNPDFAPIRF
HRGCVVSPFKMTEAEQVWQYAKLLYKIRAGAHFIITQLGYDVCKFEELSRFLLEQEVTMP
VLANVFVPSLTVARYMAKGQVPGIVFPDRLLAEIEQETERGDREARLVRAAKMVCVLRGL
GFAGVHLGGNGLSFDDVRFIMDTSEEFTPQWDRYRADIHFPGGGTWYYYPPARTGACGRT
RIGLRPGRHRAAQIPHRIMHRLLFSPPNLPSTLFGAFCRKCAHSRPATLLLRTLEKLIKD
ILFSCRMCGDCTLTDSTYLCPQSGCPKNLLNGACGGSRNEACEVFPDRACFWVRVYNRVD
PAATLVQLGNLPHLPPKDWSLNQTSSWINFYCGRDHHHLPGASTRG
>A0A828YH46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTRKQVDAELRGFQDAGIDNILALRGDIPKSGRVS
TDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A241WE59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 3813|TrEMBL
MSQLFSYFQQNKFCVLVEYLSSFNEVFPVKTVFAGYPAMMTLADRVHSDHDMAPLDASRQ
YPDAVEKVLHFAGKGRDIQDLEYFLQQAKAADIQNLLLLTGDKLKEHHKGNDSAERSRYL
ESVNAVMAAKESGGFCIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDIEAL
KQAQAFLKRHHYTQNILACVMPLSLARANFMLKHKVAGIVITPHMLKVLAEEKQAGLSER
VYLRCALQILICQHLGFAGVDLSACHKPEEQMLLESYIEEYRHLDLHALEALWTSLWQIK
TGKELMPEPADFSRPPSSGQIMKYHQLHVMHDAFFDSKIAKGVGRFIFNSPFWERRAAAK
TLLKTEHISKHSIVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVEQTEILKDKLIATVPIEVRGTSSWKNWYLTSEA
>A0A839TP40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus rhizosphaerae|TrEMBL
MKPDLRQAWDQQVLIGDGAMGTFLYQMGFPVGISYEELNLTSPEVIKDVHRRYVEAGAQI
IETNTFSANFDKLSKYGLESKVEDINRAGVRIAREVAGSAGYVVGAIGSIRGGKRTNVST
TELKKYFEQQIQALLQEGVDGILLETFYDVEELYLALSIVRKLSPLPVICQFAVEDVART
LDGYTMPEAFRMMQQQGADVIGFNCRTGPNGIMSAMKTLGGHLSVPMSVYPNAGVADYVD
GEYQYGAKPDYFGQMAVKFADLGARIIGGCCGTTPAHIAAISSALQGYEPQPITYGPIDI
VPAPIEIHEHLAPDGNGEGEGAKTNLVDLVKERHTVIVELDPPRDLDIAKFMKGAQVLKD
AGADALTLADNSLAVTRMSNMALGHLVQAQTGLRPLVHIACRDRNLIGTQSHLMGFDALG
IDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFVVGAA
FNPHGKHLDKAVLRLERKIAAGADYIMTQPVYDPELIRALKEATSHLDIPIFLGIMPLAS
GRNAEYLHNEVPGIQLSDDVRRRMSGLEGEEGRAMGVAIAKELLDVAMEHFNGIYLMTPF
MLYDMSAQLISHVWEKSGRRQPPLFHR
>A0A2S5HME9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus laterosporus|TrEMBL
MGKRDLRAYLTEHLLVGDGAMATQLYEQGVPIGVSYEELCLSNPQIIRNVHTAYYEAGAR
LIETNTFGANRDSLSRYGLENKVTRMNRAAVTIAREAVGDDAFVVGAMGSIIAGRVRDKQ
IDQFKDQFEEQATSLLHAGVDGILLETFLDVDELLLALEVIRPLTELPIIAQLATLEVGT
TRDGHSLTQAFQLIKEAGADVIGLNCRLGPAEILRSFEATVCPNDVYLSAFPNAGRLGLA
DGTLSYKSSPDYFAESALRLHEQGVRLIGGCCGTTPEHTRAIAEKLARCVPVPRVNPPVS
VHSETIEVQAVQKRLEPSIIEEVKHHPTIIVEFDPPKDLHTEDFLQGCCALHAAGANAIT
LADNSLATVRMSNMALGAMMKRLGVEPLLHIACRDRNLIGQQSHLMGLHALGIDQVLVIT
GDPSRFGDLPGASSVYDVSSFDLIRMVKQLNQGYAFSGKQLKQHAQFIVGAAFNPHVRHL
DAAVARLEKKVEAGADYIMTQPVYDAETIVQIYEATKHIRVPIFIGIMPLTSSRNAEFLH
NEVPGIKLSTYALEQMKLFTGEAARQEGNRMAKELIDVTLQYFNGIYLITPFNYYQMTVE
LTQHIRQQEQVKAGFKEVSSS
>A0A241W0T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 3813|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKKRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGNHFKIEVAAYPEMHPQADSFDLDIKRFCDKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>M7NBM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cesiribacter andamanensis AMV16|TrEMBL
MKITEHLSSASNTLFSFEVLPPLRGQSIHSLYEHMDPLMEFKPPFVDVTYHREEYVYKKR
ENGLLEKVSVRKRPGTVGICAAIKNRYNVDTVPHMICGGFTKSETENALIDLDYLGIDNV
LVLRGDPIKSESTFTPEPDGHPYAIDLVHQVRNMNRGIYLHEEMENAAPSNFCIGVAGYP
EKHEEAPNLRTDIRYLKAKMEAGADYIVTQMFFDNSKYIRFVEMCREEGITAPIIPGLKP
ITVRRQLAILPKIFHIDIPDALVLELEKCKTDAEARQVGINWSIQQSRELMEWGVPCLHY
YSMGKSDSVYRIARELF
>A9WVE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235)|TrEMBL
MTCIGNTADQLAAIITDLLEHGVRGILALRGDKPAEESEAHPTGALNYAQDLIELVRRVE
QRRSAMLAAGKVAIGVAAYPAKHPESPSERHDIEVLLAKQRSGADFAITQVFFHAEQYAD
LVMRARRAGVSIPIIPGVMPFTSLRRLERLGQLTGVEPAPELMASLASASSDSERRRVGV
QATVKLANAALDAGAPGIHLYTFNQHQAALDVLDNLNLLRPTRPAGRLRHFSRTN
>A0A412P922|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides intestinalis|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELACEAMKCKTDEEAKQVGIEWCVKQCKELMEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A2E2HSR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium|TrEMBL
MTTNAPISFEFFPTKTEAGHEKLLATAQTLAAAGPEFFSVTYGAGGSTREGTRRTVLQLD
GEVKVPTAPHLSCVGDSREDLRNLINDYRANGIQRIVALRGDLPSGMGHASGELRYANEL
VEFIRAETGDHFTIEVAAYPESHPQAPNFETDLQNFIRKARAGADSAITQYFFNADCYFH
FVDRVRQAGVDIPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDSISAFG
TEVISQLCERLLDGGAPGLHFYTLNQAEPSLAVVRNLQGDR
>I0JZN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylacidiphilum fumariolicum (strain SolV)|TrEMBL
MATLIDRLNESLLIGDGALGTYLYSLGIPRGYCIEELSLSHPDLLEKVHRDYIDAGAKII
RTNTAESNAYHLSFFKLEKKLKEIVSRSVQLAKKALGSREGWIAGTVGPIWTKPTESPID
MATRQSLYEELIASLIEEGVDLLFFETFTELPELLLVLDIARKKGAEKLFAFIASFEEGK
LSSGETLGEAFSKLRLAGATLVGINGACGVQASIHLLEEIELKAGDFLGAYPNAGKPEFY
DGTFTYSASPSYFGENVARFAEEGVCLLGGDYGTEPAHIAAMAQRAATIKPLKEKPPKRR
PRYLVSEQEVLPQIEPSLLDLLALKPVFMVEYDSPKTLAIGKFLEGVKAIEKAGADAITL
ADNSLAILRISNFAAAIHVRRVSKMIPILHVACRDRNLLGLQSELMGLGTLGFRHILALT
GDPAKSGDHPGATSVYDLNSVGLIRLLASLNRGFNAAGKDLKGKTDFIIGCAFNPNTTQF
EAQVKKLEAKLAAGAQFVMTQPVFDIQLIKKTYNYLKPLGIPVFIGLMPLLNYRNAEFLH
NEVPGISIPEAVREKLKALDGEKATELGVGFAQLLGEEILSLFKCVYLITPFLRYDISVR
LLELLYSRKKS
>A0A542AN18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. KNHs216|TrEMBL
MKISEILNSGRVTVSCELFPPKKDDDIARVNEVVRDISALRPDFMSVTYGAGGGTSQNTT
RIASEIQNCGVTALAHLTCVSSTKEEVGQILSGLKEHHIENILALRGDIPHNSDFPSPGQ
YRYAGELVRQIREYGGFCIGAACYPEGHVECARREDDIGYLKEKVDSGCDFLTTQMFFDN
NILYQFLYRILAKGIHIPVVAGIMPVTNSGQIRRICALSGTELPPRFKAIVDKFADKPAA
MKQAGIAYATEQIIDLISNGVSAIHIYTMNKPDIAAKIMDNLSEIIRE
>A0A3Q9U8S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella sp. LY|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1C5X1F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKIIDRLREEKIHISFEVFPPKNQDGFEKVLTATNKIAELHPAFISVTYGAGGGTSKNTA
KIASHIKRDLGVESIAHLTCVSSTKEEVREVIANLKKLDIENILALRGDIPAGMQFPSGE
RFHYAYELIEEIKKQGDFCVGAACYPEGHVENEHKVDDIKYLKHKVDCGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPE
AMRQAGIAYATDQIIDLLANGVRNIHIYSMNKPEIACAIMRNLSEIVKCQG
>A0A4R4EH48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus albiflavus|TrEMBL
MKLDLRTALQSTVLVGDGAMGTLLYQQGFPVGISYEELNILHPEVIANVHKQYYDAGARV
IETNTFSANREKLSKFGLENEVAAINKAGVELARQAVGSDAYVIGSIGSIWSARRINIRI
ETLEEAFKEQITALLEAGPDGLLLETFYHMSEMELALRLIREVSDIPVICQFATEGTMNT
LDGVPLQDAFDRLAAMGADVIGFNCHIGPYGIMRTIEKITPPIGIPFSVFPNAGMPDYAD
GVVTFGATPGYFAECAPQFAALGAKIIGGCCGTTPEHIAAIAQALSGVDAADTAAAARPK
APSTESAAVAEKPAVHEQQGEVSIADVIKPPAKPTLLDIVKQRHTVIVELDPPRDLDISK
FMRGAQALKDAGADAVTMADNSLAVTRMSNMALGQMVQAECGARPLIHIAGRDRNLIGTQ
SHLMGLDALGIDHVLAVTGDPSRFGDLPGSSSVYDLSSFDMIRLIKQLNEGIAFSGKPLK
RKANFRIGAALNPNVKLLDKAIQRMERKISLGADYIMTQPIYDPALIERLYESTKHLDIP
IFVGIMPLASGRNAEYLHNEVPGIVLSDDIRKRMTGLEGAEGRKVGVEIAKELLDVTMHY
FKGIYLITPFLYYEMSTELTKYVWEKASACTAQQNELQ
>A0A7C7JN20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquificales bacterium|TrEMBL
MKICEYLKEGRFSLSYEFFPPKDERGKEQLFNTLERLLKYNPNFVSVTYGAGGSTRERTF
ATVKEIKEKYNLTVMPHLTCVAHDEDEVLELLDRYREIGIENILALRGDRPKDNPKEGFC
KYAVDLIRLIKSHYGDQFCIGVACYPEGHQEAKSLEEDIEHLKEKVEAGGEFAITQMFFR
NEDFFRFKELLQKKGIDIPVIVGVMPITNFKQIKKFADLCGATIPLDLARRLSEVQDKPE
EVFKIGVDYAIRQCEELLDHGVDGFHFYTLNRAEATERIIEALRDKIFSLRKV
>A0A6N3AV25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MFIHEMFQQKPCVFSVEVFPPKKAGAAEETLYPVLRELCTLGPDYISVTYGAGGGTAGQS
TAKIASYIKNGLHVEALAHLTCVNSTRVQVEETLTRLREDNVENVLALRGDINPDLPRRM
DFLHASDLAKAIAQTGGFGVAGACYPEGHVESPSLKADVESLRYKAEAGVSHLITQLFFD
NVSYYRFLNMARKAGISLPVQAGIMPIVSKRQIERTVALSSASLPPQFTKMISRYDHDEQ
ALFDAGIEYAVTQIRDLITGGADGIHLYAMNNARVARLVYEGIRDLLPERT
>B5VWI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnospira maxima CS-328|TrEMBL
MNRFRTACLNPKEFVITAEVAPPKGGDPTHMIEMARGLKNRVHGVNITDGSRAVLGMSSL
ASCVILQHHGIEPILQVACRDRNRIGLQADLLGAHALGIRNILALTGDPVKAGDHVNAKP
VFDFESVRLLQAINKLNNGMDWNDKKLPHGRTDLFPGAAVDPQSPSFSGLQSRFYRKLKA
GACFFQSQLITDFERLYKFMNQVASDTDKPILAGIFLLKSAKNALFINKYVPGVNIPDHI
IHRLEKSSHPLEEGIKIAAEQVQIARQICRGVHLMAVKREDLIPKILDAANIPPLP
>A0A8J3W3W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planobispora longispora|TrEMBL
MPTVRELLAAGGRSFSFEFFPPKTDEGERQLWRAIRELEALRPTFVSVTYGAGGTTRDRT
VEIVERLAHETTLTPVAHFTAVNHSVRELRHLIGRFAGAGVRNILAVRGDPPGDPMGEWV
AHPEGVLYAEDLVRLIRQSGDFCVGVAAFPYKHPRSASVESDTEYFVRKCQAGADYAITQ
MFFRAEDYLRLRDRVAARGCDTPIIPGIMPVTQMSTIARSEQLSGAPFPPEVAARFEAVA
DDPAAVRRLGVEHAAELCQTLLDEGAPGIHFITFNRSSATREVFQAIDSSRETAPLTA
>A0A1C6GEH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKIKDVLKDNKVHISFEVFPPKTEAAYDSVLSATEKIASLKPAFISVTYGAGGGTSKNTV
KIASKIKEDFGVPSLAHLTCVSSTKEEVHQVIDRLKENGIENILALRGDIPKSTEFPLPN
HYKYAYELIEDIKAQGDFCIGAACYPEGHVETEHKKDDIRHLKQKVDCGVDFLTTQMFFD
NSILYNFLYRIREQGITIPVLPGIMPVTNGKQVKRICELSGTILPERFRAIVDHFGENPE
AMKQAGIAYATDQIIDLIANGIQCIHVYSMNKPEVAGAIMNNLSEILKA
>A0A2X4TPM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus coprophilus|TrEMBL
MDRTNLLVDVLGTVGLQRSRHLGPPYRSPAGVAEHRTGKPAPYAEWVENDLVRATEDGGE
SRTPSIVDRLGAARTGRIPFSVEFSPPRDADAEARLWRAVRTFERLGPAFVSMTYGAGGS
TRDRTVRVTGDLAEETTLLPVAHLTAVGHSIDEIRAMVGAYADRGITNILALRGDPPGNP
LGEWEKHPDGLEHADELVRLVRDLGDFHVGVASFPEGHHRSPDLDHDTRYLVRKLRAGAE
YSITQMFFDVEHYLRLRDRVEACDPEQAAKPIIPEIMPITSLRSARRSLELSGSKLPPSL
EERLVRAAGDGPEEDRAAVREVGIEVATEMCERLIAEGAPCLHFITLNFARATSEVLTRL
GIEVRSTVPAGQPV
>A0A1H6SFZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium terrigena|TrEMBL
MKVTEHIEKANGKPLFSFEILPPLKGQNIQSIYDSIDPLMEFNPPFIDVTYHREEYEFKE
LPNGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGINN
VVALRGDAVKSEIYFKPEKEGHAFASELVSQINDLNNGIYLDADLQNSSKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNQKFFDFVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMAVVKAKDNEAVKQIGIEWCIQQSTELVAAGIPVLH
YYSMGKADNIKAIASKIF
>A0A1F8IKD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacterales bacterium RIFOXYB1_FULL_67_16|TrEMBL
MATSTNLAEARALLLSPLGPVARAGSNRDAVRVSFEFFPPKTDEAEASLWTAIRRLEPLN
PAFVSVTYGAGGSTRERTHRTVQRIIAETSLRPAAHLTCVEASRDEVDEVIAGYKTIGVD
HIVALRGDPPGGGGIGGVYQPRTDGYANATELTAAISRIGGFDVTVGAYPEKHPESPSID
HDIDVLKAKVDAGATRAISQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLQRM
SGACGTSIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRADLV
YAICRVLGVRETKAAA
>A0A1C7I931|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia pseudococcoides|TrEMBL
MNISELFQRGEFVVSAEVGPPKGINIDHLVEEAKTYLSGVTAVNVTDNQSSVMRLGSLAT
CKVLKDEGLTPIYQLTCRDRNRIALQSDLLSAAMLGIENLLLLTGDHTKMGDHPQAKPVF
DLDSVSLIHTVKQLESGYDLGGNELVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVMAGA
DYFQTQAVFEPEKFISFMEKAKQFGKPVQLGIIIPKSVGMARFMNANVAGIHVPESMIDE
LKADKEKTKAGITGVEIAARIIKECKPYCQGIHIMALGWESKVPDLLKQAGL
>D2NQ24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia mucilaginosa (strain DY-18)|TrEMBL
MVMTTVHPALSFELFPPRSQASCESLLRTIAELEGTNPDYVSVTYAGDAKRRQKTLALLD
HLVHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQDGQVSELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVF
FEDERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSS
AELHRIGVDYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSEL
EFA
>A0A5N5DQW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lasiodiplodia theobromae|TrEMBL
MHISQKLYEGQKNGKPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPTFIDVTWGAGGRNS
TLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALREAYNAGCKNILALRGDPPREKEK
WEATAGGFRYAKDLVKYIRDNYGDHFDIGVAGYSEGCEDQDDPNLLLDHLKEKVDAGGTF
IVTQMFYDVDLFLDWVKKVRAKGITIPIVPGIMPIHTYAAFMRRATWTKCRVPPDWLEAL
EPVKNDDAEVREIGKHLIANMCRRLMEAGIIHLHFYTMNLAQSTRMVLEELGLTPDMYSP
LEKPLPWRQSLAPGRREENVRPIFWRNRNRSYVVRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNIKLWGSPKSVRDIANLFVRYMEGKLDSLPWSEQPITAEADVLKDNLVN
LNKRGLLTINSQPAVNSAKSTHPVHGWGPHNGYVYQKAYLEVLVSPELIAELITRIERDP
EMTYYAVNKAGDLKTNAPSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEFYRLGEDW
AKCYTSASPSRYVIEDIMDTWYLVNIVHNDFHVENGIFALFDGLEVKDLDKELHGSANGE
VNGNGHSTASGVAHTNGESKIPDTIVNGKSTSAVQNGTAN
>G7G4Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. BSi20495|TrEMBL
MDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVIIYDIQDESSRTNQDRP
FAFKQTVDPREYSHLLRNLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDLQNVVLVGSP
SSIGDIKLSLPDAYKAMAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQGCQFFISQA
VYDAQATIELITSYARTCKAQGITPQRIILTFTPCGGEKTLEFMQWLGISVPEATKWRML
DADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINLYRLLKAIME
LNLAEKLIA
>A0A2G3PQN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia marianensis|TrEMBL
MVFGPCGGVRDDATCEMDAHICPFAVLTEPIPWPQPLTSPASPSELINASRARPVVLSDL
SVPAFDRGVLEQVASILGESSDAVLVGEHQNRPDYPPTVMAQIIRGVGGCPWVTLTCRDR
NRVVLEQELMGLGQAGADGVFCVTGDGRAQGVRQDVTQVFDLDGTRLAALAAQADLAVGV
PEAPEAVPTSIRPARLLEKQRAGAQLAVLNHVSTPESLRAFMSTARTQGVTMPVIAGVAV
YTDERSAQVLAAFPGLHLDHSQITRVLAADDSVEAGIETAVDEAVALLDIPGVVGVNLSG
LASAAGEVPAAKVKAEIGRRLRERLAVGHNR
>A0A416CHH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium AF36-19BH|TrEMBL
MIKDLFSQKQTLSFEVFPPKKDDEFTNAQNVLHQLSELQPDFISVTYGAGGSRSKRTVEL
ASFIQNSLHIPAVAHMTCVGSSKEDILTVTDDMKQAGLSHVLALRGDRPTWMDDAQFENR
AFAHASDLTRFLKEHTDLEIAGACYPEKHFEAESLDADIAYLKEKQEAGAAFFITQLFFE
NDSFYRFLEKKNHTGITLPVCAGIMPITSAKQLGTTVTLSGSSVPKELADIIATYGENPE
DMRKAGIDYAIRQILDLKQHGVDGIHIYSMNKPKTTRTIVEAIR
>A0A7C6KEF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MNTNISIEFFPPQTPEGVEKLRATRAELAKLKPEFFSVTYGAGGSTRERTFAIVREIASE
GFDAAPHLSCIGSTRESIREILAEFKAAGIRRIVALRGDLPSGMAEAGEFRYANELVEFI
RAETGSHFSLEVAAYPEWHPQARSPKDDLDAFARKVKAGATSAITQYFYNADAYFHFVDE
ARALGVDIPIVPGIMPIVGFTKLARFSDACGADLPRWMRKKFESFGDDSDSIRAFGLDLV
TELCERLLKGGAPGLHFYSMNQSALTCEICRRLGLPQTA
>A0A1H9WXR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacillus sp. OK032|TrEMBL
MGLLDKLQTNMLTADGAMGTLLYSFGIDYCNEELNIERPEIIEKIHQDYIAAGADIIQTN
TYGANSIKLARYGLEDRVKEINEAAIQIAKRAAAPGGQFVLGTIGGIRGIRKSDATLEEI
IQMVDSQANHLLTGNPDGLLLETYYDFDELSATVTHLRKLTNTPIIAQVSMHEPGILQNG
LSLNDALHQLDALGADVVGVNCRLGPFHTIQALEEVTLPKNAFLSAFPNASLLDIEEGRI
VYESEADYFGQAALLLREEGVRLIGGCCGTTPKHIEAAKKRIGQLAPLTTKVVAPKKPII
IRDAEPNINEPLHEKAQRERTIIVELDTPRHLDTTTFMEGATKLYDAGVDAVTMADNSLA
SPRISNMAMGSMLKLQNNIRPLAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKI
GDFPGATSVYDVSSLELIQLIKQLNEGISFSGKSLRKKANFSVAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVYTKEKIQEIYEATKHLTTPIFIGIMPLTNIRNSEFLHNEVPGI
KLSDDVLARMRACGEDRERATAEGIQISKELIDTAAELFQGIYIITPFFRYDMSLELIAH
IKEIDSKKARENSYVQTSN
>A0A1F9BLA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_50_11|TrEMBL
MENNRFKQALSEKKEFIYTLELVPGRGSRGKTQDEILKIAEKAARSRLVHALSITDNPGG
HPALSPNVIGLEISRLGIDPLIHFTCKDKNRNQIESTLYFLDRAGISNLLLMTGDFPLYG
FEGKAKPVFDLDSVQLIHLINQMNLGLEIDGKAPGGGVRLPPTHFFKGCTVSPFKKSEPE
VMAQYYRLYKKVKNGADFAITQVGFDARKFDEVHRYMRDYALRVPILGNVYVLNHPVAKV
MNRWGVPGCVVTDDLYRIIEEEAKTPDRGRATRLTRAAKLIALLKGMGYDGAHLGGPNLT
YEDVEWIIETSKELSPNWEAYVREFSFPQKDGFYLFEKDRKTGLNTDNPTYKRSHPRKAP
GHTLMRFFHHLAFTTEAPLYKLARWVFKKIDGTWLEGPVTELEYWIKFISSRCRRCGDCT
LLEVAFLCPQSQCPKYLFNGQCGGSVEGWCEVFPRKKKCIYVRAYDRLKPYGEEESLKES
YTPPRNWALDQISSWANYFLGRDHHGQKLSSE
>A0A7Y5FRE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriaceae bacterium|TrEMBL
MKVTEILSNAKEPLISFEIIPPQRGGDIKSLLAVIEDVAQYKPPFIDITSHAAEIIYEET
PKGIRKRVIRKRPGTLGICALIQNKYNIEAVPHILCRNFTREETEDFLIELSYLGIENVL
AIQGDDKGFVKEIPHGRSTNIYAIDLVKQVVQMNKGKYLEEELLDAKPSNFCIGVSGYPE
KHFAAPNLKTDISHTKAKIDAGADYVVTQMFFDNKAYFSYVEKMREAGVTAPVIPGLKIV
TQKSHLTILPKNFFLNIPEDLSGEILEAKPEHVLEIGVNWAAKQVEELLDNGVPSIHFYI
MQYSKPIKMLMNKLKLHEKKFFVTKK
>A0A6J7PHV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSTRPTISIELFPPKDSAGEERLWSAIASLREISPDYVAVTYGAGGSTRDRTIRITSEIT
ARTQLPTVAHLTCVGSTRDELIDVLNKYKSAGIRSILALRGDPQGGPSAAWTATPDGLDH
ADQLVALASEVGGFTIGVAAFPDGHPASQGNFDRDIEVLLRKEDLGATFATTQFFFTAEK
YFDLVERLRSRGSHLTVMPGIMPISNVKQLIRMAELSGTPIPSDVEQKFLALDGDSDAVR
DYGRELATTLCQKLLAGGAPGLHFYTMNTSTATKEIFENLGL
>A0A6J6BE74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSTSPMPTTTTAVQRQLVAEARYELIPLKNVDAQIAHVPAGSSVSVTCSPAKGLQATLDL
TAKILDQGYEAVPHFSARLTEDAAHVRRLAEFCRTHALREVFLVAGDAPEPVGPYDGVVA
FLRDFLDTDHGLQRIGITAYPDGHALIDRDVVHRALHDKQALLAEAGVPGFASTQMCFDV
DQWKRWAAAERAAGFTLPLHLGVPGVIDRAKLLTMGARLGIGSSMRFVKKNSGTIFKLFS
PTGYDPSKLIAPMSKVARDLGIEGLHVFTFNNVEATAAWQRKQLAKLS
>A0A6J7J6H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRIDDILRQGPDPVFSFEFFPPRTPEGEANLYEAIAKLAPMDPAYVSVTYGAGGSTAGKT
LEIASTIRERHGIEAMAHFTCVGATVDELRATLDEMRELGFENVLALRGDPPAGQDEWVR
TDGGFEYSRELVELINADYAMTVGAAAFPETHIHATSPEDDLRHLKAKVDAGVDFLITQL
FFDNAVYFDFVERARAIGIDVPIIPGILPITNIAQLDRITSLCGSEVPARLRAELDLRTD
EPEAVEDFGVAYATLQCAELLAGGAPGIHFYTLNRSPATRAIVGALRLQRPWDTAGA
>A0A6J6LCI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MATAIAIKQLGLEPILQIVCRDKNRLAQQADIMGASMFGVENFVALTGDDVTAGDEPEAR
RVFDTDGPQLVRLMGTLKRGEYMSGRKIDPAPHMFIGAVENPGAPPFEYRVQRVAKKYAA
GAKFLQLQICYHQDRLEKFCAGVRDAGLAGKIAIIPTVVLVKGARPLNFMHNSVPGIDVP
ADQIARVEKAADPAEEAYLQTLEFAQHALAQPGVRGLHITDFRNDETLERLMSDLGRIRQ
VTTSSSIPNEVKDDHAYSA
>A0A6J5ZVX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRGDPVGGPTAPWVTTPGGFDFADQLVALAADVGGFSIGVAAFPDVHPASDGNFVQDVNV
LLRKEELGATFAITQFVFDSGRYEALRNALDQRGSKLSIYPGIMPVTSYPQIVKMLELSG
GYMPKATRLRFARYQNDAVSLKKLGIDVAVQICEDVFALGAEGLHFYTLNNAGPTGEIIK
QLSMLSR
>A1SAG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)|TrEMBL
MAFHHAQHANSLNQNLAEVGDINVSFEFFPPSTPEMEKILWNSIRRLEPLNPKFVSVTYG
ANSGVRDRTHGVIERIQQETQLVAAPHLTLVDASDEELLALAKNYWHQGIRNIVALRGDL
PAGSPKPTRFAADLVRLLKSVADFDISVAAYPEVHPEAANAQADLVNLKRKIDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAAMTNVSIPGWLHRQFEG
LENDAATRQLVGANVAIDMVKVLAREGVKDFHFYTLNRAELSYAICHTLGVRPKQD
>A0A7K7N8B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haliaeetus albicilla|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQESGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRYLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNFG
VEQAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A0E3NHP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina thermophila CHTI-55|TrEMBL
MLTNFREKLNSGKFLVTAEVSPPKGTRFSGSLEDARYLKGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNVCLMTGDYPSCGDHPGSKP
VYDLDSVQLLQLVRKLDSGIDFAGNKLDGGTSFCAGAVTGIDPGKTIQLIKLEKKVRCGA
EFIQTQAVYDVGMFEEFMEVTSHLEVPIIAGLIPLKSFSMAQFMNKYISGISVPEEIMSR
IKDAPDPVEEGLSIASETIKELMKLSRGVHIMPVGSHKNTPRLLSMAGILGND
>A0A2G8D8N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia sp. OLMDLW33|TrEMBL
MSFFHANQREALNQSLAEINGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRNIAQDYWNNGIRHIVALRGD
LPPGAGKPEMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFAAMTNVRVPGWMTSMFE
GLDNDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPETVVNA
>L7ET52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces turgidiscabies Car8|TrEMBL
MALGTASTRTDHARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVSDTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNILAVR
GDPPGDPMAEWVPHPSGLTYAAELVRLIKESGDFCVGVAAFPETHPRSPDRDTDVTHFVD
KCRAGADYAITQMFFHPESYLRLRDAVAAAGCPTPVIPEVMPVTSVRMLERLPQLSNAAI
PSTLKERILTAKDDAAAVRSIGIEFATEFCARLLAEGIPGLHFITLNNSTASLEIYENLG
LHHPQRA
>A0A101PMZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces canus|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPMAEWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWEGDVTHFVD
KCRAGADYAITQMFFQPESYLRLRDRVHAAGCETPVIPEIMPVTSVRMLERLPQLSNAII
PSVLKERILTAKDDPTAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A2G6MJ62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus propionicus|TrEMBL
MRIPELLNRGGQSLSLEFFPPKKQDDWPDFLETAGQLKVLAPSFVSVTYGAGGSTQDATL
EICRQLMDHCSYEVMPHLTGVAADTDKIDQFLATLKALGVDNVLALRGDRPQGFSGDDQE
LFAHFPHASDLVSYVHSSQPEMAVGVAGFPEGHAECSSIAKDLEVMREKVESGASFVITQ
LYFDNRVYFDYVERLRCRGIRLPIIPGILPVRNLASLRFILQLCNARIPGQLINALLKAD
EEGGSKAVYATGVSYARQQIKELLQGGAPGVHLYTLNKADMCLEVMAGLY
>A0A3A6MSV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. OF03-11BH|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEIAKIIY
>A0A5P9PIS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. YIM 10|TrEMBL
MTDMTSVVERLRGNETVFSVEFFPPRDDADEAILWRSIRELEGFDPAYMSITYGAGGTSR
DGTIRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNVLALRGDPPGDPYG
EWIAHPDGLNYAEELVSLVRSLGDFCVGVSAFPYGHPRSADLETDTRHLVRKFNAGADFA
IAQLFFEAEDFLRLRDRVAAAGSDALMIPGIMPLTTPRTLRKTIELSGAAAPKRLLDRLS
PLEDDAAAFRAEGLDVVTELCERLIAEGVPDLHFYTFNRSKATREVVSRLGLIPARA
>A0A3D5VWU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax sp|TrEMBL
MFANDRIPLSLEFFPPKTPEGAEKLRGVRQQLYALQPEFCSVTFGAGGSTQEGTFGAVRE
ILAEGVSAASHFSCIGATKDTVRAQLATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDL
VAFIRAETGDDFHIEVAAYPEVHPQAKSPASDLQAFSAKVKAGANSAITQYFYNSDAYFR
FVEEVDALGLEVPVVPGIMPITSSTQLMRFSDASGAEIPRWIRLRLQSYGDDVASIKAFG
LEVVTDLCEQLRAGGAPALHFYTMNQSAATLALCQNLGLSAS
>A0A5B1M7C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides antri|TrEMBL
MLTRTRADVVRRLLANARFEVLPTARVEEAVATHLRPGRTVTVTASPSKGLEATLALTER
LTARGYDVVPHLAARMITGRSELVEIADRLRASGVTTVFVPAGDADPVGSYAGALDLLDD
LVAIGSPFAQVGITGYPESHPTIHDDVTVQTMWDKRRHATQIVSNLTFDPRVLTSWVQRV
RARGVTTPILVGLPGPVDRTKLLSMATKIGVGESTKFLAKNRGVFARIAAPGGYDPLRLL
NRAAGVLGDERMNVTGLHLFTFNQVAETEAWRRAQLARWER
>A0A7G1PB70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces glomeroaurantiacus|TrEMBL
MRDMLATGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGTTRAGTVKA
TEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPLADWVAHP
QGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDTDVANFVDKCRAGADYAITQMFF
QPDAYLKLRDRVDAAGCRTPVIPEVMPVTSVKMLERLPKLSNAAFPDALKERILTARDDP
AAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTASLEIYENLGLHHPQQA
>A0A7L0PJ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesembrinibis cayennensis|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGTGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A440RRV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MEKAAIRPSSIGASIEMAPSQVIDSPDLPGLFPSGVRVYITDIGLADTPTLVKAARRVAD
LGYTAVPHMAARRLTTRQALETRVKALAEEAGVRDLLIIGGDVATPAGSFSSSFEVLETG
FVDKYGIAEVGVAGHPEGSRDFGDEAAIAALRMKSAWAERTGAKMRVVTQFGFDADKFIA
WADGLAVSGVDLPIHLGVAGTAKITTLLKYAALCGVGNSLNFLKKRSASLAALATSHSPE
SFVGPIEHHLRAKPESAIAQLHVFPFGGIKNTARWLYERGSWQDLEADDRSSIA
>A0A8J6NKD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfatibia profunda|TrEMBL
MHLKRKFDTGEFAILAELDPPKGVDVSTMVTNARRVKGNVDAFVVPEMSNAVMRMSSLGG
AMILQKEGMETVMQLNCRDRNRIALQADLLAAYGCGITSVMAVTGEDPSYGDHHQARSVY
DIDLLELLRAVKSLQEGRDMAGIELEGSPRFLVGSTVDAGAKGKSPELVLEEMNQKVDAG
AEFFITPPLFDLSAIEPFVKRVDLQKIKIIPTVLLLKSLGMARYIQRNVDHVYIPDALIA
RIQKSPEKVRECIRIASEIAKTLQQEGFGGVLLATIGWEHKLPEIIDRM
>A0A1M5UEL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio aerogenes CECT 7868|TrEMBL
MGYTHAGHIDALNQNIAELSDDINVSFEFFPPSTPKMEETLWNSVHRLKDLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLVAAPHLTCIDASREELCHIADDYWENGIHNIVALRGD
IPPGGGKPEMYAADLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKIEAGANRA
ITQFFFDIECYLRFRDRCAATGIDVEIVPGILPVSNFKQASRFAAMNHVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPVQQTA
>A0A7C8BWM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoclavibacter sp. CFCC 13796|TrEMBL
MTASAQPAADRRPQVARSNDAAVSTGASAEEPIAERRFSASRFGLSGEDAFDDGDDAADA
LHAPAAHITPAWDTLPSVEAPTLSLEVFPARGVPQLRRNVAAVRKLLKLGPDFVTVTYGA
AGSRQEGTKELVTWIAQSGVPTYAHLTCQATSLRELDETIDELLEAGVTGILALRGDARD
DGSGLVLPHATDLIARVSQRAEAAGQRIRIVGAAFPTGHPDSQDLREDAENVARKQQAGA
DFAITQHFFDAEDYARFLDLVAETGATLPIVPGLTPTTTVRRLERISELSGLTPPPALAA
ALGAAPDAQTRRDIAVQNTVELAEKLARAGAPGIQLFTMNDEPTALRVFDALSSSPAGAL
GQNTGREPWLLNTQGPALKAALH
>A0A413KM62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus anginosus|TrEMBL
MSIQSPSLSFEVFPPNPAVGNENIMVALKEMQDLAPHFISVTASNNKFNIEETTVRLADF
ICNGLHIPTIAHLPAVYLTKEMVTETLTVLDKIGVHKVLALRGDILRDVEPQKDFVYATD
LIEYIKKEAPHFEIIGACYLEGHPDSPDRVSNIKNLKKKVDAGCSSLVTQLFFDNERFYD
FQERCTLAGIEVPIHAGIIPILNRNQVLRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSSTAHQIYQATHTFFNNKVSS
>A0A668UHK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oreochromis aureus|TrEMBL
MVNQVQRGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQSKEKITGYLAKAKHLGLKNIMALRGDPVGEDWEEEEDGFNYAID
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNY
GIQQAVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELQNEESVFEVFTSYITAQPNHCGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVNGRNLTNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWGK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPELHKATEV
>A0A1F8TE10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_19FT_COMBO_56_12|TrEMBL
MNGNPNSKFFTWLDQSRTPLLGDGAMGTMLNSRGVGFNQCFDALNLTNPALVADIHRAYI
EAGAQIIQTNTFGANRYKLAEHNLEDKVEQINRAGVELARRVILASFKEVLLAGDVGPLG
VHLAPFGRVQPEQARQVFAEQIGALCAAGADLLILETFSDLHEISEALAAARGVCDLPII
ASLTFTRDDCTLLGDSPAKVATTLHAAGADVIGVNCSGGPAQIWRIFRQMHGAVPEARFS
AMPNAGWPERVGGRIMYPASPDYFGEYALAFHQAGVSLIGGCCGTTPQHIAALREALQNP
MSGNALNGVGISLVESEAVATAFEKPSQFAQKLADGKFVVSVEMDPPRGLSTHKLLAGAS
LLAEAGADVINVADSPMARMRMSPWAVCSVIQREFNIETVLHFPTRGRNLLRVQGDLLAA
HALGIRNVFVVMGDPTEIGDYPDAMDDYDLVPSGLIKLIKEGFNVGVDHAGVEIGQPTSF
FVGCALNLTAPDLDLEVKNLRRKIKAGADFILTQPVFQPLLVEPFLKRYTELSSPIEIPI
LVGVLPLFSPRHAAFLHNEVPGIEIPEEIHARLKKAGESAPQVGIRIATELIDQMRSWAS
GIYLMPAFNRYDLAAEVIEAVNK
>A0A532E2X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
QSQYCFDVPMFRAYMQKVCDLGYTEKCFILCGVGPLASAKTAKWIRSNVPGIHIPDQIVK
RLEGAQDQKREGKQLCIDIINEVKEIPGVSGVHVMAYRQEEYVAEIVDESGVLKGRRPWK
REIRRDDQLVADRLDHILHDDLTETQVDMVKTAH
>A0A2E4EVC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MPPVTGDPGQPLPVLEGHVSAGRLERVLRSGKFAVTAEIAPPDAADAEAVYERASVFDGC
VDAINATDGSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVTN
ILCLTGDGVQAGDQPDAKPVFDFDCISLLQTVTAMRDEGEFLSGRKLTTPPRVFLGAAAN
PFGPPLDYRPIRLEKKINAGAQFVQTQYCFDLVRLREYMSRVRDMGLTERCYILVGIGPM
PSARTASWIRDNVPGVHIPDAVIKRLLGAENQKEEGVRICVEMIQAVREIEGVHGVHIMA
YKQEERVRDIVEESGVLEGRIPWYPGXXNDQQGQQT
>A0A413EBS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella parvula|TrEMBL
MTLREKHQQGQFTITVELDPPKSSSAEKTFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDAPTNFYIGATGNPGAPDLEIERQKLAAKIQNGA
HFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
MEKGGKEAGTEIAIETLEQIKKMAAGVHIMPLNDIDTTLYIIDHV
>A0A2E7ZXM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MSRLAQALSMSEFVVTSELIPPKGVDLEPLFEKAQALNQVVTAFNLTESHTAKMSMDPVA
VGHLLLDRGVEPIVQMTSRDKNRIAIQASILGAAALGISNIVIMGGDPPKNGDHPDAKGV
FDLYSSQVLDAASALNGGADYMGNPLKGAPAMNIGAVVNPGAADPSAEIDNLHRKIEAGA
GFFQSQAVYDVDALASFLNKADTDAAILAGIIPIKSVRMARFMNDKVPGIDIPETLITEI
EAAGDDPERLAETSIDIAARIIRQIRPLVKGVHIMAIGWEDKIPAIIQRALD
>A0A1Q6VIU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium 13_2_20CM_1_69_27|TrEMBL
MGPYPEATAVFDIDSIGLTNLVYRLNHGLDPGNNPIGGPTSWAIGVGVNPGAVELDRELS
RFHWKVDAGAEFAVTQPVFDVRQLESFLKRVDAYRIPIVAGIWPLVSLRNAEFLANEVPG
VVVPAEVLDRMRRAQDKGKEAALAEGVKIAREMFQQVKGSVQGVQVSAPFGRVEVALEVF
G
>A0A3B9DTW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dialister sp|TrEMBL
MSTLKEKNQNHIFTITTELDPPKSASSAITEEQAQKVAPYVDAVNIADCPMAKMRMSPIA
LSCIIQQKYQVESIFHLTCRDRNVIGLQAELLGAAALGVHNILTLTGDPPKIGDHPNAKG
VFEIDSTGLIQIASCLNSGHDIEGHDLGAATDFYIGTTGNPGTDDLDAEIKRLESKKKAG
AQFIQTQPIYDIKQAEDFLACAKDLDLPILFGIVPLKSFKMANYLNDKVPGITIPAKVLS
QMETGGRETGLAISKEIVTALREIHAAGAHLMPVNDIDAIPYIVGDK
>A0A0P9GP07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. atrofaciens|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>C5FI42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthroderma otae (strain ATCC MYA-4605 / CBS 113480)|TrEMBL
MEKISDKIEALPKDAHYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEETKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFSHAVDLVRYIRKKYGDYFCIGVAGYPEGHADESHPEVQDPLKDLPYL
IEKTQAGADFIMTQLTYDIEAYRKYEDLLRNHESGTFKTIPIIPGLMPIQSYHTLTRVTK
LSHAKIPPEILAKVEACKADDEVVKRVGVDIVSELVEGIKKISTPGHRGFHFYTLNLEKS
VSFILERCNLIPPSSEAPSDNELEFELAVSDRSSTVHETSALTAGYPALNPPNRNTTLQI
SEGLGSLGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTARVARKLWGTPTSREDIS
NIFRRLLSGELHAVPWSEGGAGEEGGLNPETATIRTELLKLVEGRGWWTLASQPSVNGVR
NDHPIFGWGPRGEGFVFQKAFVEFFCPGDDFHSKLKPLLNSYGHDEFAWFAMNAKGDFQS
STSPEPPASPPTDSTEPLFDTDPLTDMDNGSVNAVTWGVFRGKEIVTPTIIEAVSFRAWG
EEAFGIWEEWRRIFPRGSASEKLIRDVKDDVWLVCVVGQRFGAGGEVGKESNEDDGQLLW
KVLADAWKAAMSSEVLLFLFTVKHPSPLVSDPGLNDYMKINVQRRKKYLAVFIQN
>A0A529T9V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
AKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFLGCAVNPFAPPYDFRPIHLGKK
IAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLCGVGPLASAKTAKWIRSNVPGI
HIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAGIHVMAYRQEEYVAEIVDESGV
LKGRQPWQREIRRDDQLVAERLDHILHDEITETQVDMVKTAH
>A0A433NVZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium polaris|TrEMBL
MIITVTVNGVAGMSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEDTLWSSIDRL
SSLKPKFVSVTYGANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWE
SGIRHIVALRGDLPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLIN
LKHKIDAGANRAITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTN
VRVPNWMTSMFDGLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICH
TLGVRPDVAR
>A0A543IWI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermopolyspora flexuosa|TrEMBL
MPPSADARYLEGERTPMAIQQEVSGSGRRGSTLADLVRNIGYEVMPFKKTEQDVLTHVPK
DVPLTVTVTVAKGIDTTLDLAERLHNHGYTVAPHLPARQFVDAKHVEDVVARLKEAGIRR
VFCIGGDAPTPAGEFTESYQLLRVLQELNHPFENIGIGGYPEGHALIPQNAIDEALRKKA
PMADRILTQICFDANTTATWAKRIASEGVNLPIYVGMPGPVNRQKLIRISAGIGLGQSAR
FLQKQSNLLWRFLLPGVYNPTKLLKRLASASAKIGGNIRGLHIFTFNELEGTEKWRQKLL
ASVAGRDDR
>A0A7Z9N4P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIRDKVKRPRRPVVVYEILPPREKDGTLDSYAEIISSLLSQTHIDAINIPEVRDEYGRG
ERPVKSQARAEPREFGQLLQDIVGIEAIVNRVVVHQPIEEEMRWVEETYKKYEIENLIVV
GGESSKIDYPGPSVNTALRAITGQINTDGGDIFCGGISIPSRVKESKNMIRKGENGSEFF
TTQVLYDSSKITKMISHYQVRCRELNTFPRRLLLSFAPVSSQKNIEFLKWLGVEIPEDTE
ACLKGDSAAMIERSLDVAVKVLNETLGYIKENNLAVPIGLNVEHIMSYNFQASVEMLQEL
ARIYREFCIKAENY
>A0A839J7Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propioniciclava sp. MC1683|TrEMBL
MPETIVDRLRSSDGPTFSVEFFPPSDDAGVQQLIGTVDQLQGLQPDWVSVTYGATGASRY
KTFSAVGAIRGQTAVSTMGHLTIAGQSAAEVVRAIQAYERLGVTHILALRGDPPSGGRFA
PHPEGLRTATDLVRLVKSLGDFTVGVAAFPDGHPEGDLDLDARILLAKEQAGAEFAITQL
FFDPAAYVSLVGRFRALGGTMPIIAGIMPVTVPSQIERFAGLSGSAMPADFEARLRAVAD
DKAAFRAVGIDLVTQLCRDVLDAGAPGLQFFTLNRSTATAEILGRLRTEA
>A0A800CCK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiaceae bacterium|TrEMBL
MDTSNKKAPSISFELFPPKTETGMEKLKLVVAELNKLDPEYFSVTYGAGGSTQDRTFATV
DWLREQGIDTAPHLSCIGTDKGEILDILERYLGQGIKRIVALRGDLPSGSGLGGLGELNF
ANELVALIRQTFDDAFHIEVAAYPEFHPQAESAQADLDNFRRKVESGAHGAITQYFYNAD
AYWRFLDDCQQRGIEIPIVPGIMPITNYSSLARFSDACGAEIPRWIRKRLESYGDDLSSI
QAFGAEVVTTLCRQLLDGGAPGLHFYTMNQSASVLQICAALGITNGENAS
>A0A7C7NYA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVTDFLKNADKPLFSYEIMPPLRGGSADKIFSMVEKLMPFNPPFIDLTSRSAEVEYIDT
PNGQIEQHVRRKRPGTIGLSAAIKNRFDVETVPHVLCNGFTREETEDALIELNYLGIHNV
LAVRGDDLRRNMTTNGKTTNKCASDLVCQIQKMNQGEYLDKLLDASATDFSVGVGGYPEK
HFEAVDMNTDLMYLKEKVDNGADYIVTQMFYENKSYFDFVEQARAVGITVPIIPGLKIIS
TKRHLKLIPEFFYIKIPDELGKQVEEAKTNDEVKNIGVNWAIEQTKELYEANVPCIHF
>A0A423VNM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytospora leucostoma|TrEMBL
MDKITDKIAALPPDANYFSLEFFPPKTQMGFANLRSRLERMARALKPTFVNVTWGAGGST
AQKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALEDAKALGIRNILALRGDPPRRAE
YMDENDEDDLGGEDEYKWAVDLVRHIRKTHGDYFCIGVAGYPEGHADESHPLGQSMEHDL
PSLVEKVQAGADFIMTQLFFDIKAYEKFETTLREHPSGAFKDIIIVPGLMPIQNYQMIKR
TTKLSHARIPDDLMARLEDVQRDDERVKMVGVDILSELIEQIREIKSRTPGPKGFHFYTL
NLEKAVSFILERTNLIPPQTPEGEQALVDDLINTIPKVEINGSNGSTSQHHLGINSASRR
QSNVSSEPRNRVIVSGERTPSNPEYEATQLEASRPYEPVHSRANTLAISEGEGALGREAT
WDDFPNGRWGDSRSPAYGEIDGYGVSLHMSVTQARSLWGAPKSVEDIGTLFIRHLQGELR
AIPWSEAEFNDETDTIKDQLVALNSKGWWTVASQPAVDGLPSTDPTFGWGPANGFVFQKA
FVEFFMPADQWKKLHEKLLKPELKDSIWFYAANAAGDLIMPDVSSGVEHEPREEGTNAVT
WGVFPGKEIVTPTIVEEVSFRAWAEEAFGIWGEWGQVYGKGSESAQFLEKMKNELWLVNI
IHHEYVEPEALWDLLLNA
>A0A379IKS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETADHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCETLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>E6TN68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium gilvum (strain DSM 45189 / LMG 24558 / Spyr1)|TrEMBL
MTQPVTERDAGRDCPKRMTFGPCGGVHPDGQCEMRPGPCAFPDIVPWPTQAAPPPVTAPL
ILTDFSCTPFDPHDVAATANALAPSCDAVLVGEHQNRPDFPPTLMSRLLLDAGVTPWITL
SCRDRNRVVLEQELRGLSLLGVQTVLCVTGDGRAYDVRPDVTQTFDLDGPRLVELAASLA
MVAAVPETPTAPPVARRPLRLVHKQHAGAGIAVLNHVSSPSTVAEFMAAARAAGLVIPVL
AAVAVFTDDVSAAVLQGLPGLALDRAVVDRVLAAPDPVEAGIEAAVAEARALLAIDGVAG
VNVSGLASGAGTRVGAQIKAEVGARIRAERSVR
>A0A544Z4I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbispora hainanensis|TrEMBL
MALGLPSRLPDRVPTVRELLAAGERSFSFEFMPPKTDEGERQLWRAIRELEGLRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPRGGNPLDEWVKHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSATIESDTKYFV
QKCRAGADYAITQMFFRAEDYLRLRDRVAAHGCDTPIIPGIMPVTQMSTIARSEQLSGAP
FPPEVAERFEAVADDPAAVRRLGIEHAVELCRKLLDEGAPGIHFITFNRSSATREVFQAL
HSVPAAVAG
>A0A2E5JSN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKIIDYLNNADKTLFSYEIIPPYRGGSIXKVFELVEQLMPFNPPFIDLTSRSAESYHQDD
GDGKLVQRIRRKRPGTIGISAAIKNKFNVETVPHILCNGFTKEETEDALIELNYLGINNI
LAVRGDKLRKAPLSEKNNHYASDLVKQIKDMNSGQYLEPLXDXFKTDFCIGVGGYPEKHF
EAINMKTDLKQLKKKVENGADYIVTQMFYDNKAYFNFVKRCRDEGIDVPIIPGIKILSME
SHLEVLPKFFHIDLPAELINAVQGKSKSEIKNAGIDWTVNQVNELIXAKVPCXHFYIMTS
AKXAXXVVSQFI
>A0A2E2Z3A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIRDKIKRPRRPVVVYEILPPREKDGTLNSYAEIISSLLSQTHIDAINIPEVRDESMRG
ARPVKNKTRAEPREFGKLLQDIVGIEAIVNRVVVHQPIEEEINWIEETYKIYEIENLIVV
GGESSKINYIGPTVNSALRAINSRIDTNGCDIFCGGITIPSRLKESKSLINKSKNGSEFF
TTQVLYDSSKIKRMMSHYQVRCNKTNTFPRRLLLSFAPVSSQKNIEFLKWLGVEXPDKTE
SYLKGHPASMIERSLNVAVGVLNETLDHIKENDLTVPIGLNVEHIMSYNFQASVEMLQEL
ARIYREFCIKTENY
>A0A7C7BYP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirales bacterium|TrEMBL
MTHNIPRLREALATKPFVTTIEFNPPKGTDASKVMTLAGKMVGMVDGVNVTDNTAAVLRA
GSISLCRLLYEIGHDPVMQITCRDRNRLAIQSDLLSAHLLGIRNLLCLTGDYPTVGDYKD
AKPVYDIDSIQMMQIIDGMNKGHDMNGKTLRGVTELYIGAAMSPDMEPSGLAKTKFETKV
NAGASFFQTQAIFDADRFKEFMTFARQFNVKVIAGIILLRSAKMARFLNDNIPGLTVPQD
LIGELEAAPDDKACDIGIDIAVRIINAIHDSCDGVHLMTITAIDRLPDLIKRAE
>F2SQ86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892)|TrEMBL
MHIKDKLALAEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMPRERVDDALQSAFKAGCTNILALRGDPPREKEA
WEQTEGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFLDWVKKCRQAGIKVPIIPGIMPISTYAAFIRRTNWVKCAVPKGWMEAL
EPVKNDDAAVKQIGKALVSEMCRKLLENGINHLHFYTMNLAQSTTMVLEELNLKPSTETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSVRDLSDIFVRFLEHKLDRLPWSESAITQESEIIKDDLID
LNNRGFLTINSQPAINGAKSSHPIYGWGPRNGYVYQKAYLELLISPALIDEVVRRIESNA
DLTYHCINKDGELKTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSASRKLIQNTMDTWYLVNIVNNDFHKTHDIFDLFKGLVLKDIDTEVSGTQQATE
PAENGTHSEDPASKSEKQAVSAN
>C3AQL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pseudomycoides|TrEMBL
MKILDLVSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADIIQTN
TYGANEAKLRMYGLENQVTQINKAAVKLAKAAVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEKVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQLALHEAGATQNGN
DVNGILTQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPAHIEGMKRVIANVTPVTEKQIVQRQQVVH
IQTKRASTHITLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIEEIYEATKHLEKPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMDGHETQESAIEEGIRISQELINAAMKYFNGIYLITPFLKYEITENLVKYVK
EKQDVKEGIN
>A0A0E0UWG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes serotype 4a (strain M7)|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNTSLPEMQE
GKVIYQSDTDYFEHYGEIFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A2U1U114|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brenneria sp. CFCC 11842|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASRDHLREIAQDYWRSGIRHIVALRGD
LPAGGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRVPNWMTAMFD
GLDNDPETRKMVGAAIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAVA
>A0A1P8EFZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter soli|TrEMBL
MTKHVPISFEFFPPKTDIGAEKLITAHQDLQQLQPEFFSITYGAGGSTRERTLAAIKEFN
GKGTPVAPHLSCIGDDKARIAELLDLYVAQGINKIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAETFDQDIQRFTEKVNAGANSAITQFFFNPDAYFYFL
DRLQKQGITIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSRSIRAFGHE
VILKLCERLIDGGAPSLHFYTMNTTEPTRQLVVDLGLN
>A0A357EFQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
LTGDYPTVGDHKEAKPVYDLDSVQVMQLVQGLNNGKDMMGNKLDGSTAFTIGAAVTPEAD
LIGPVLAKFEVKVKAGAQFFQTQAVYNPDVFASFMKQVRPFNVKVLAGILVLRNHKMAEF
MNANIPGMAVPKEMIDELKAAGDRAEDVGVDIAVRSIKAVRPHCDGVHLMAIKATHRLAE
IITKAELG
>A0A1I8C7Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhabditophanes sp. KR3021|TrEMBL
MSPNLEKVEKNAVNQKEVKEVTFQIGNAEYSPTLSRNASEYNLEIDERNLTPYVPLHKRI
NNQIELGNPFFSLEFFPPKTDRFRDGGPMFVDITWHLGSDPANLEKETSSSSIAQSCLDY
CRLDTMLHMTCAQYDKQQTLDHLKQCKKMGLRNILALKGDIAESDDSLPEAEKVKAKYYA
LDMIKWIKKEYGDYFTVACSGYPLAHPDAKSYTADLEYLKAKVDAGADFIITQLFFEVAT
FEKFVRDCREIGIKCPILPGIMPIQGYASIKRIAYLSKLEIPQNIVDDLEALKHDDEAVL
KYGIHRAVEMCRKLLNDKTAPSLHMYTMNRESAIREILVQLGLWKQYAIKLLPWVPHGAH
HPNRFAESCRPIYWSARPKSYIFRTRAWDTYPNGRWSHSSSPSYREIDLFYLKGHQSKDK
QLKMYGYQLESAKDVSNVFVRFLTQELNENGVQVNQLPWNENEGKISHETQFIKKDLLWC
NQNGILTINSQPQVNQAQSEDVIVGWGQAGGYCYQKAYLEFFVSKEVALKLQNLIESSYA
KRINYQIINNTGSIDYNNYNGTNPNVLTWGVFPGSEIAQPTVVDPLSFRAWKDEAFDVFN
TWATIYPADSVSRKTLQTIHDEYCLVTLVDNDYVKQTVIYKLLQKVINS
>A0A532EQJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPRRLREVLDQGQFAVTIEYNPPKGTNISGVLENAKQLVGRVHGVNVTDNTAAVVRA
GSLSVCRLLYELGHDPVMQMTCRDRNRIGIQSDLMGASMLGLRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGKDMAGNKLDGSTAFMIGAAVTPEADPLGPMLAKFEVKV
KAGAQFFQTQAIYHPEQFASFMKAVRPFKAKVLAGILVLRNAKMAEFMNANIPGVSVPQE
MIDELRAAGPERAEDVGVDIAVRTIKAVRSHCDGVHIMAIKATHRLAEIITKAEVG
>A0A0Q6TJT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelomonas sp. Root1217|TrEMBL
MTAVSFEFFPPNTPVGVEKLKTVVQELGAMSPQYFSVTYGAGGSTRDKTLSAVMDIAAAG
FNAAPHLSCVGSTRENIAEILATYRAQDIHRVVALRGDLPSGTATAGEFRYASELVGFIR
ETQGKDWHIEVAAYPEVHPQQRYAARDLQHFVDKMKAGADGAITQFFFNADAYFHFVDEA
RRLGVTQPIVPGIMPFHNYGRIAQFAQRDGIDIPRWVQMKMEGFMDDAASIRAFGLDVIT
RLCERLIDGGAPGIHFYTLNQSALTLELCKRLGLGNKV
>A0A661XE69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldiserica bacterium|TrEMBL
MKITEIFKKKGFLLTCEIGPPKGYKMDSVIEKILDLKDFIDAFNVTDFQGSTMRMSSPFA
SYILKKNGFEVIMQLTTRDRNRIALQGDLLGAFSLGIENVLALTGDPPSVGDHPEAKPVF
DIGSSELISVIKKLNEGYDMMGNRLEEKTDFCIGCAANPCVENIDEEFGKLEKKIKAGAE
FIQTQAVYEVERFSKFIEKFRKNFGNIPVLVGIVFIKSAKMAKYMNENIPGIFVPEYLIK
EISKFDSEEIKERKRKAAKIMEKIVIELKETPIDGFHFMPLGWYESVRYLFESLKEEKVF
>A0A1V6BSX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin139|TrEMBL
MKLTELFEVSEKTFSFEFYPPRDEIAAVDFGLNIGQLIKLSPSFVSVTYGAGGSTQSRTF
DLVDYLKNRVGLNTVAHYTCVGSTRSKTLEDLKTLRKLGLQNFMLLRGDPEVGSKYGFIP
CYDGFSNATELISFAREYIDGCCIGGGAYPEVHPESPSAEIDMKNLKKKVDAGCDFLITQ
FFFDNKRYFDFVARARKAGIKCRIIPGIIPLTKYAQLERFVNLSRASVPPAFLEQLESNR
YNPDAVYKAGMDFAIRQCRDLLMLGAPGLHFYTLNKSRATVEIYQTLMVW
>A0A2L2WJL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. MGM1|TrEMBL
MTVAELINSDRSRRHFSFEVLPPLKGTGTEKLFATIEKLKAFDPLFINITTHHSEFVYKQ
LDNGLLERSSVRRRPGTIAIAAAIQSRFGIPVMPHVICSGATVEDIEYELLDLQFLGISS
LLLLRGDKAREDRHFTPTPGGHAHTTDLIGQVRRFNDGFFADGSPVKCPGQPFDFGVACY
PEKHEEAPNIEMDMRRLKEKQDRGASFAVTQLFYDNRKYFDFVDKARAMGITIPIIPGIK
PFAKLSQLSVVPKTFHCDIPDELARRAVVCATDEEARMLGIDWAERQCRELYAHGVNNIH
FYTVSAVDSVVEVARRLMER
>A0A849FHI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter sp|TrEMBL
MKVTDHILNAKGETLFSFELIPPVKGRNIKELYNNIDPLMEFNPPFIDVTTSREEYIYID
REGLLDKKLTRMRPGTVGICASIKHKYNVDTVPHVLCGGFTKEETEYLLIDCHYLGIENV
MALRGDARREEKYFEPTKGGHPYAVNLVKQIKDLNCGKYLHEVIETNDCANFCIGVAGYP
EKHLEAPSLQSDLKRLKQKIDAGADYVVTQMFFDNTKFFEFVKAARKIGISVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVDECKDNKAVRQVGIDWAIQQSQELKAAGVPVLHY
YSMGKSDNIQAIARGVF
>A0A7M3MAX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanidesulfovibrio indonesiensis|TrEMBL
MRIADKMTGVDKFVSFEFFPPKEREKWDDFFHEARRLREVNPLFVSVTYGAGGTTQDNTL
EIVKKLKNEIGLEPMAHLTCVGADEKAIGEFLDQLAENDVNNVLALRGDPPKGEKSFIPS
DARFCHANDLVDFIKERHPEMGVGVAGYPEVHPEAESAMSDLEALKVKIQAGSDLIVTQL
FFDNALYFDYATKVKAMGVMQPIIPGILPVLSLASVERIVELCGASIPEDFLESLKAAHE
EDKAAKEEGEPGGRVRALGIAHAKKQVAELLEGGAPGVHLYTLNKADACLEIVRSPEVCK
HLKDCAEPVA
>A0A848HLW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia polaris|TrEMBL
METHNFSIEFFPPKTAEGAEKLRVVREKLALLNPKYFSVTFGAGGSTQQGTLDTVLEIKQ
AGYVAAPHLSCVGGTRESIRAILQQFKENGIDRLVALRGDLPSGYGGGGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQARSPQDDMQNFARKVKAGANAAITQYFYNADAYFAFMD
EARKLGVDVPVVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASYGDDSASIKAFGLDV
VSQMCERLLKGGAPGLHFYSMNQAVATTALWERIAGR
>A0A853GXS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas harenae|TrEMBL
MSSKQAVSLEFFPPRDIAAQEKLVRSAKQLLALHPTYVSVTFGAGGSTRTGTVDTVRLMQ
NLGCNAAPHLSCIGASRAELAEILDMYREQGIRRIVALRGDLPSGMGGDGGDLHYASELV
AFIREHSSDWFHIEVAAYPEMHPQASSAQADLDYFVNKVQAGANSAITQYFFNADAYYDF
VDRVEARGVSVPIVPGIMPITNYTQLSRFSNMCGAEIPRWIRLRLADFGDDKASIKDFGV
EVISRLSQDLLDNGAPGLHFYTLNNAEVTMAVWKRLSLDG
>K6ZUD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraglaciecola polaris LMG 21857|TrEMBL
MVSYAQGIDALNQSLSEVKGINVSFEFFPPKTETMEQTLWKSVERLAPLKPKYMSVTYGA
NSGERDRTHEIVKRIQSETGIAAAPHLTCVDASRDELKQIAKDYWASGIRKIVALRGDLP
EGYTEHVSYASDLVALLRDVADFDIAVAAYPEKHPEAPNSQFDLLNLKRKAEAGANQAIS
QFFFDAEVFLRFRDRAAAAGIDMDIVPGILPVTNYQTLQRFAGFTNVHVPNWLHKMYDGL
DKDDQTTRNLMGASIAMDMVKVLAKEGIRDFHFYTLNRCELSYAICHMLGVRAD
>A0A5M5PMX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEDARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A3R6SI35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF20-17LB|TrEMBL
MNLREYLKETNLITDGAFGTYFAAKYQTQEIPELANLSDPEKVKKIHEEYLNAGANFIRT
NTFAANTETLQESFPEVEKNIRAAVEIARSAAEGKNVWIAGDIGPIPVNGTEDAAAAADE
YYEIAKTFAETGVKVLDFETFADLDGILPAIKKIRAEYDMFIAVSFSVNQFGYSAAGLSA
KRLLADAAAVPGIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPVYFAEKMKELQELGADILGGCCGTDPEFIREMFAWDGILKKGAPEKEAESSGQSEP
VVRQGFLYDENGNRKEKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMANKVRQATGLNVMPHICCRDRNAIAMRSLFLGAAINDIYNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTEGDAVRLRRIKDETGARILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKASRKEGEAVGIQLAKEVMKLVEDFADGYYFSFPFNRVYMLKDILEK
>A0A0A1WKV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zeugodacus cucurbitae|TrEMBL
MEEDMQYLKEKVNAGADFIITQICFSPESIIRFVQRCRENGITVPIIVGVIVPDNMRILQ
FIMKIVKAVIPEDLLSKYKELEDDRKAFQAFAVENAVRTVQMLLDSNLEVYGFQF
>A0A8F1GTV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia muciniphila|TrEMBL
MHLRERLQSGAGPSLSFEFFPPKNEQAAAALYQTIRELEPYHPSFVSVTYGAGGSTRELT
REVVLRIQHESRIPTVPHLTCVGHSREEVWSILDQYAQAGVRAVLALRGDPPRGTENYNR
DADAFRHAAELVAFIREYNESGRHPDPDGFAIGVAGFPEGHPSTPNRLREMDFLKAKVDA
GADYICTQLFFDNHSFLDYRERCLLAGIKVPILAGIMPVTSLSGMNRMAELSGGTCFPAR
LLKALKRAGSNPDAVQEVGIQYASSQCAELLDSGVAGIHFYTLNQSRATRQIYRNLGLKD
SLQLLEHGEDK
>A0A1I0CLE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio sp. C4|TrEMBL
MFKDMFANDSSLSFEVFPPKKDDEFENCYKVLDSLSELKPDFISVTYGAGGSRSKKTVEI
ASYIQNELHTDAMAHMTCVGSSSEDILAVTRDLEAVGVNHVLALRGDKPRDMSDEQFNKR
VFPHATDLIRFLNENTKLDISASCYPEKHPEAMSMDSDLAFMKMKQDMGAKMFISQLFFD
NADFYRFTERADKAGITIPIVAGIMPITSAKQIGSTVTLAGSSVPKKLADICARYGESPD
DMRKAGIEYAID
>G6YSC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter manganoxydans MnI7-9|TrEMBL
MTLVSERQAFNRPDEEAAARFRDLVRSASIEATPRQILTTEHLPDLLPAGTCVYVPFLPK
GQFSDTLEASRRLLDLGMQPVPHVPARMAQSRGQLRDWLAQLDESGVDRLLLIAGDSDAV
AGPFPDTLAVLESGLLAQFRFQGIGVAAHPDGHPMADRATLAKALSVKREYARTTATRLW
VVTQFTFDADVVIDWLQGLGNILEEVPVYIGMAGPTRVKTLIAYAAMCGVGASARMLLRR
PGSARMLGAWKPDDMVRALVQYCLENPETLLRGIHLFPFGGLRQSAQWILDHSGSCENNR
EAVP
>B4W334|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coleofasciculus chthonoplastes PCC 7420|TrEMBL
MTNLTQPSFRDAVKSGKFLITAEVSPPKGGDASQMINLAKPLKNRVHAVNLTDGSRAVLR
MSSLAAAAILVQHGIEPICQIACRDRNRLGLQADLMGAQALGIRNILALTGDPVKVGDHP
DAKPVFDLESVRLLQLISKLNNGFDANDKPLSDGKTELFAGAAVDPQLKSWSGLQRRFER
KLEAGAQFFQSQLIADFQRLEMFMDKIAADTDKPILAGIFLIKSAKNARFLNKYVPGVNI
PQSIIDRLAEAADPLQEGMKIAAEQIKLAQQLCQGVHIMVIKREDLIPQILDLAEIQPLN
R
>A0A2G1YGE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter sp|TrEMBL
MKVTEHIKKANGKTLFSFEIVPPVKGKNIQSLYDNIDPLMEFNPPFIDVTTSREEYIYIE
KDGLLDKKMTRMRPGTIGICASLQHKYAVDTVPHVLCGGFTREETEYMLVDCQYLGIDNV
MALRGDAMREEKYFVPAKGGHTYAHELVSQIADLNRGNYLHDDITMEHLPNFCIGIAGYP
EKHMEAPSLQSDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVEAAKKLGINIPIIPGIKP
IAVKRHLSILPPVFKIDLPQDLIDAVDACADNKGVRQVGIEWAIQQSKELKTSGVPVLHY
YSMGKSDNIQAIAKDIF
>A0A1G7UCM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas taeanensis|TrEMBL
MSAHEHPLGISFEFFPPNTEAGKEKLLGVRDALAARDPRFFSVTYGAGGSTQARTTQTVK
SVRESGINTAPHLSCIGSDKGAIRELLAQYREDDINSLVALRGDLPSGMGGGGIGELRYA
NELVEFIREETGNHFEIAVAAYPESHPQAQNFERDLENFARKVKAGANLAITQYFFNPDA
YFHFVERARKLGVEVPIIPGIMPITNYTKLARFSDACGADIPRWVRKQLEAYGDDSASIQ
AFGEEVVTRLCERLLDGGAPGLHFYTLNQAQASLKVLDNLRA
>L9L5F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tupaia chinensis|TrEMBL
MVNEGSSSGSESSKDSSRCSTPGLDPERHEKLQEKMRRRMESGDKWFSLEFFPPRTAQGA
VNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCQQ
SQEEITGHLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYAVDLVKHIRNEFGDYFDIC
VAGYPKGHPEAESLEADLKRLKEKVSAGADFIITQLFFEADTFFRFVKACTEIGITCPIL
PGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASG
LVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKS
YIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELASEESVFE
VFAHYLSGEPNQQGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPS
SDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPE
LQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIH
DNYFLVNLVDNEFPQDNCLWQVVEDTFELLNRPTQNESETVAP
>A0A1H2WLX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidaminococcus fermentans|TrEMBL
MKIIDLLKSPKVCVSCELFPPKKGSELEHAQEIVRTIAIQGVDYMSVTYGAGGTAVGKSV
ALVSEIERCGVPALAHLTCVGADEGKIEGVLDQLKDAHVENVLALRGDLPQGQDHPLGDY
AHASDLVKKIKSYGDFCVGGATYPEGHPEAAGLDEDLEHTKMKVEAGCDFLVTQMFFDNS
MFYNFMYRLLAKGIQVPVVAGIMPVTNLKQIEKIFTLSGTPVPAPLRAMAERFADHPAAL
KQAGMAYAIGQIVDLIANGFTNIHIYTMNKPEIIGGIRSNLSEIIRC
>A0A2G7LTE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. LK1|TrEMBL
MKADLRSVMQERVLIGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
HETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGANGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGVPMSVYPNAGAADYVD
GQFRYGASPEYFGQTAVQFADLGARIIGGCCGTTPDHIAAIAQALVEYTPVPILEPDPSE
SKPRIILHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVSFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLEVPIFVGVMPLASGRN
AEYLHNEVPGIHLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATKHFKGIYLMTPFMFY
SMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A1G3G645|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium RIFCSPHIGHO2_02_FULL_62_130|TrEMBL
MSAPRISFEFFPPQSLDASFRLWETVQALAPMAPNFVSVTYGAGGTTRKVTHEAVSAIHR
NYGLNVAAHLTCVDATRVETLEIAAAYAEAGVTEIVALRGDAPKGATRFTPHADGFANSV
ELVEALAKTGKFKLRVGAYPEPHPDAADSFADVAWLKRKIDAGATSAITQFFFDADTFFR
FRDACVKAGIDAPIIPGILPIQSWDGAKRFAARCGTKVPVKLDEAFTTAARDGRENLLAL
TQCTSLCDRLIQGGVQDLHFYTLNRPNLTREVVRALGIAPEVALEKVA
>A0A1I2KRM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. DSM 46838|TrEMBL
MKRVLTVRDGATRESLKRAVDDLGFEVIPFKKTEQAVLEHVPTDVRLTVTASPAKGQDAT
IDLTVALVGHGYSVAPHLSAQQVRDRAHLADIVARCREAGITDVFVVGGDPTDEPTGFAD
AHALLVALHELDHGFTDIGIGGHPEGHPSAPTDVLFQALKDKAPLATHIKTQIVFDPKII
LDWARELKRRGIDLPVHVGVPGAVTRQKLMRVSGGLGIGESAKFLKKQQNLFWRFFIPGG
YSPNKIIKGLAPHIGKPDNAIEGFHVFTFNDLGPTEAWRQQMLKDLA
>A0A1X3JNH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia albertii B156|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPESGKPEMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A2G6LYD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Fermentibacteria bacterium|TrEMBL
MRIADLYKSRKPVVSLEVFPPKPGKSLDSIYKTLNGLKELEPSFVSVTYASQNSSGKRTV
EIASTVRDRYRMESLAHLTCAGQTEEQVDDILETLREKGISNILALRGDIPDTGEKKLSD
FVWASQLIKRITDFGGFCTGAAAYPEGHFESKRISHDLSNLKKKTDAGAEFLITQLFFDN
RIFYDFIERAEASGISVPVIPGLMPVLNYRQIKRILMMCRVSVPAALLELFDRYADDPES
LASAGVDYAIEQVADLVREGVPGIHLYTMNRIEQIKQIVRTSGLRQ
>C0QT51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Persephonella marina (strain DSM 14350 / EX-H1)|TrEMBL
MKIGEILKHINTSISFEFFPPKTPEGEDQLFRTIKDLEKLNPTFVSVTYGAGGSTRERTI
RVVKRIHEQCNLTVMAHLTCIGHSKKEIYDILKGYKDIGIQNILALRGDIPQGQEESFVF
PPDGCRYANELVSFIREQFGDYFSIGVAAYPEGHPESPSLEKDIYYFKKKVEAGAEFAIT
QMFFDNSYFYRYMDLLSKEGINIPVIPGIMPITNFRQIEKFAVMCGATIPKDLVEKLEKV
ENSPEEVAKIGIDYATEQCEDLLKNGVKGLHFYTLNKSKATVEIYRRIKDLIK
>A0A2K8VM01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sejongensis|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVD
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VVALRGDARKDESYFKATQGGNAFASDLVQQISDLNKGKYLHDDIKVEHNYDFCVGVAGY
PEKHMESPSLNTDLKRLKQKVDAGADYVVTQMFFDNNKYFEFVKKAREIGITVPIIPGIK
PLAVKRHLQVLPQVFKIDLPEDLIDAVEGCKDNKAVRQVGIEFAIQQSKELKEAGVPFLH
YYSMGKSDNIHAIASKLF
>A0A2M7J7C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG_4_8_14_3_um_filter_50_9|TrEMBL
MRIAEKLEASERGVSFECFPPKTEKGRSNLYGALGALEKYKPLFVSVTYGAGGGNRDTAV
DTVLSLKKDFTFEVMPHLTCIGAPASEIDGVLDTYKDAGIENILALRGDPPSALEGFDES
RGVFAHASDLIKHIKNEYSFSAGAAFYPEGHFQSPSPADDITHLAGKFAAGADFGISQMF
FDNRHYYDFLDRAAKAGIKKPLIPGIMPILNFEKIKELASSSAKVAIPDKLERLMNSYSD
PEDIRKAGIDYASAQCEDLLRNGVRFFHFFVMNRAESSACIIEN
>A0A5M8NW89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Ordinivivax streblomastigis|TrEMBL
MRIIDLISNSKRTAFSFEILPPLKGTGIEKLYDTIDILREFDPQYINITTHRSEYVYTDC
GNGLYQRNRLRRRPGTVAVAAAIYNKYHITVVPHILCSGFTKEETEYVLIDLQFLQITDL
LILRGDKAKHEPVFTPEENGYLHAIELQEQINNFNQGVFIDGTKAKAPAFPFSYGVACYP
EKHEESPNIDSDIYWLKKKVETGAEYAVTQLFYDNNKYFGFIEKARRAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEALLSELLKCKNDDEAQQVGIEWCTAQCKELIAHKVPSIHF
YSVAAADSIKEVAKRIY
>A0A1G3YCZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus sp. GWE1_62_9|TrEMBL
MTERTYSFEFFPPKTAEGADKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETVREIQT
DGSEAAPHLSCIGSTEESIRDILNEYKSQGIRHLVALRGDLPSGSMDAGAFNYANELVAF
IRRETGDWFEIEVAAYPEVHPQARTYTEDLANFKRKVDAGANAAITQYFFNADAYFNFVE
DARAAGVSIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLPSLRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPTTTIWQRLGLS
>A0A067Q2S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jaapia argillacea MUCL 33604|TrEMBL
MKISKKIEQAQKENRLWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
DLTSELVRTCQSLIGMETCMHLTCTNMPAEKVDLALRDAKEHGCRNILALRGDPPMGKDE
WEAVEGGFTHGIDLVRHIRKVYGDYFDVAIAGFPQHVRLPPDEMAFEMKCLKDKVDAGVD
FIFTQMFYDADIFIDWVHEVRKAGITIPIVPGIAPIQTWNGFIKSTMLSKTTIPQALLDV
LEPHKNNDEKVRELGTKLVADMCRKILKADLGIKGLHFYTMNLERGTKMLLEELQLVPRL
ETIKPLPWRQSLTPSRRNETIRPIFWANRTKSYLSRTENWDEYPNGRYGDSRSPAYGELD
GYGVWIKQTKEEALKLWNQPTTYPEIFALFSTFCLGKLAALPWSDSPPSPETTIIAQQLA
KLNGMGFLTINSQPAVNGARSDDPKVGWGPSNGYVYQKAYLEFFVSPELLAALLPHIERD
GNITYHVINKNGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGYQ
WGRLYEHDSQTRKLITNIMDTYFLVNVVHNDFKDPEAIFKPFFKAYEQHASSQSNGNGHA
NGNGVAAVGNGHA
>A0A7X5ZR13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora amisosensis|TrEMBL
MSLAEAFAAGRFAVTAELGPPRGADPEQVEARARLLRGRVDAVNVTDNPGATVRMSSLAA
AVLVLRAGVEPVMQLTGRDRNRMAVQADLLGAGALGIPNVLLLAGDPPGAQAVPVFDLDS
VQLVWTASMLRDRGRLLSGSRVDPPPHWRIGSVENPFVPPVRERAARLGKKIAAGAEFVQ
TQFVFDVAGFARWMAAVRALGLHERCRILAGVGYPRTPAMLHHLRTGLPGVRVPDAVADR
LLGVAPRRFRQEGLRLCTEIVGRVREIEGVAGVHVMAFGDEAAVVEIVEHAGLAG
>A0A0S8G1N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium SM23_32|TrEMBL
MKSGSNLERVLRAGHFAVTVEIGPPMDCNASVVTEKARMLRGIADAFNITDNQTAVVRMS
SIASCVLIMEEGLEPVMQMTCRDRNRLAIQSDILGACALGIRNCLCIAGDHQSFGAAGRL
KGHPGAKNVYDVDSIQLVSILEGLRDKGCQQGGDPVEMRPPLLIGAAWTPLGDPIEIRPL
RLKKKVEAGADFIQTQGVYDVARFAHQMELVRNMGLHERTAILAGIIVPRSLAMLKYMNS
SVAGVSVPDSLMDRMAEAKESAGKDKKQARRNQEEEGARIAVELIQQAREVPGVKGVHIQ
AIEWEGSVPEIVDTAGLLPRPTFPQEGEGDDFDGEDPGS
>A0A838R165|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pirellulales bacterium|TrEMBL
MTIRDAYGPNRFGLSFELFPPKTPEGMTGLFNCVGELVKFDPSYITCTFGAGGSTQDRTL
EVITGVREKFNVPVATHLTCVGLTAPEIRDYLARALSQGVDNVVALRGDPPRGETEFKPV
AGGFCYGNELVAFIRSEFEEMGVAVGGYPEKHQEAPSRKVDLENLKRKVDAGADVVITQL
FYNNDDFYRFRDRCHELGINVPIVPGLLPVTNGAQIQRIAALCGAKLPPPFAAKLEKHAD
DADAQFEAGVDFAIKQSADLLANDIPGIHFYVLNKSAATRRVLTALPQIKTA
>A0A7K8YJG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sakesphorus luctuosus|TrEMBL
MVNESQQSCSGSSSSRSDGSSSGSESSKDNSRCSTPVLDTDRHERLREKMRRRQEAGDRW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDLV
KHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFVITQLFFRPETFLKF
MKDCQAMGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNRNGYRVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A2M7SFY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_10_14_0_8_um_filter_43_12|TrEMBL
MPKSFKEALESGKFVVTAEVGPPKGTDIEEMLHHIDLLKDKVDGLNVTDNQSSVMRLSSI
SVSHIIREKGGEPILQMTCRDRNRLALESDLISANILGVDNVLCLTGDYITMGDHVEAMP
VFDLDSVLLLKTVRLLESGKDSGGNELKGSARFCAGAIVTPEANPIEPQLLKFEKKIKAG
AEFFQTQAIYDLDNFKKFMRYARQFNVKILAGIVLLVSAGMARYMNANVPGIFVPKALID
EMAGTEKGKALEKGIEIAGRMIKTLKDENICDGVHIMAIGKEGKVPDILAAAGLV
>A0A249PD80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sojae CCBAU 05684|TrEMBL
MERTSLHPSERGNIRLSFEYFPPKNEEMETQLFQTVADLASFAPAFQTVTYGAGGSTKAR
SLTTVRRMIGEMGFRNTAAHMTCVGAPRSEVDAVVEEFLACGVHHFVALRGDPQGGVGSA
YQPFPGGYENAAALVKALRARGDFEISVSAYPEKHPESRDAAADIDMLKRKVDNGATRAI
TQFFFDNDHFERYLDQVRRAGIDVPIVPGILPINNLSQVMKFAGLCGSTVPDAITSRLAH
LDDQPAERFREASHIAAEQIVDLVRRGVRDFHIYTMNRSPLVAAVCELLGYVRSPVKAEE
RAVDESIKTAAGAR
>C7QYL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jonesia denitrificans (strain ATCC 14870 / DSM 20603 / BCRC 15368 / CIP 55.134 / JCM 11481 / NBRC 15587 / NCTC 10816 / Prevot 55134)|TrEMBL
MASFDVSATARGFHRPTVSFELMPPRNPAAAPKFWNTARKLVEAHPDFVSVTYGAAGGDR
DSARTVVETLVQHTNVLPIAHLTCVGATRDNVADTIDDFLAAGARTFLALRGDPPKDQPD
WAPPTNGVVSSLELIALLRDVEAQRCQADASEALRGAMKPLTIAVATFPEGNRDAGTTRE
QEAARLLQKQQAGANFAITQLFYTASAYTEFVDVARSLGVTIPIVAGILPMTDPQRLRRL
EQLTGVPVPLELAAQLDAIASPHVRHSHGIAASVDLANAVLDSGAPGLHIYTFNKHEPAL
DLLEGVHLGGSLGGVAPVRSPQPVDVAGWPQVGASPVTA
>A0A1G0HCA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_41_20|TrEMBL
MQPLRPLTISFEFFPPKTSEGLTALCETAQCLQESNPQFFSVTFGAGGSTRRGTLETVQL
LQAHTGVSIAPHLSCIGLQREEIVRILDDYQRCVVKRIVVLRGDMPSGMVQMGDVKFASE
LVRLIRDISGDYFHIEVAAYPEFHPQAISVQDDILNLKRKYEAGADSAITQYFFNADAYF
YYREDCERLAMPLPIIPGIMPITQFTKLARFSAACGAEIPRWIRKRLESYGDDLHAIREF
GMEVVYNLCQRLIAGGVSGLHFYTLNQAEAALEIVRLLGFIPAQHREVSSV
>A0A5B0WZA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. B2(2019)|TrEMBL
MTPPKASHSPEKISEIAQKQVERLKNVDLDALILYDVQEEAERVDHERPYPYLPTIDPAV
YGDKYLRQVEVPKIIYRCVGNDTRASFADWIKTDESEDRFSVYVGASSSKQEVKLNLPDA
YKLSKQLNSNLNFGGVVIPERHIKKNDEHIRVVEKINNGCNFFITQATYNVEASKNLLSD
LYYYYTNKGFEMVPILFNLAPCGTAKTLHFMKWLGISIPGWLENELKYSNDILDKSIQLS
QKIFEELFEFGLEKGIPIGCSIESVSTTKLEIEASIQLAKDVKAFLDKKLLSLESR
>A0A2S2BUL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. S2-17|TrEMBL
MTFDSVRGRASEGWVTRTPSIVDRIRSCRDGRVPFSVEFSPPRDEAAEARLWRAVREFER
LGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPEGVEYAEELVRLVRELGDFHVGVASFPEGHYRAPDLD
HDTRYLVAKLRAGAEYSITQMFFDIDDYLRLRDRVAAFDAEQGAKPIIPEIMPITSLRSV
QRVMELSGSRLPVALERRLSRAAGDGPEENRAAVREIGIDVATEMAERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSRTDPRPVTPARVS
>Q3SFY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus denitrificans (strain ATCC 25259)|TrEMBL
MTERTFSFEFFPPKTAEGVEKLRATRKQLAQLHPKFFSVTFGAGGSTRDRTLETVREIQA
DGSEAAPHLSCIGSTADNLRDILGEYKNQGIRHLVALRGDLPSGTFDAGEFNYANELVAF
IRKETGDWFEIEVAAYPEVHPQARSYGEDLANFKRKVDAGANAAITQYFFNADAYFRFVD
DARALGVSIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLESYGDDLTSIRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPSTTIWQRLGL
>A0A1G3YTW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp. GWC1_61_84|TrEMBL
MKKHIENKTYHVEILPPKQDTEKLETDLENFSVKFNRVMESGYCACLTDNAMGNLAFQGT
EMIEELGLEPRKDLVMIHLNTFHTKGDLDRILDSCRTLKIRQLLVISGDGSDRLPKLSPA
DVGATDTEAVTSVELLRYIGREYPGDFELGVAFNPYEPEEHEFAKMERKLAAGAVFIITQ
PVIERHEVVDRLLAKYPGIPVIVEAWMSKKIDLLSEAVGYEIKTATDPFDPIATLKILHK
NYLGCGVYLSLLGFKTQYDLIKDTWQ
>A0A7V6G8D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKIANILKQKKTLSFEVFPPKRETDIGNLKKTIQDLATLNPDFMSVTYGALGTTTDNSAA
IAKFIKENTKSEPLAHITGIASTKADIINLCNELKKSDIKNVLTLRGDNPENTNNLQSDF
EHASDLAAFIYEQFGDYFSCAGACYPEKHPEAVSFEVDIDNLKKKQDTGMEFFTTQLFFD
NDVFYRFLIKARKAGITVPILPGIMPVTSYKQIDRIIQVSGVLIPIQLRNYFDKYRNDKQ
ALEEIGIIFTSYQILDLLTNDIDGLHLYSMNKSHFIKKLMANISYVTTGYFANK
>A0A2W0C809|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus illinoisensis|TrEMBL
MKADLRSVLQERVLIGDGAMGTYLYQMGFPVGISYEELNLVSPEVVADVHRRYLEAGTEI
FETNTYSANYDKLSKFGLESKVTEVNRAGARIAKEVAGSNGYVLGAVGSIRGGKRTNVST
SELKRFYEQQIFALFEEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDIGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGVPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFADLGARIIGGCCGTTPDHIGAIAQALSEYNTAPIVLPDPTE
AIPRIVLHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDPQLIVAMHEATKHLEVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A1I1MYZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium uliginosum|TrEMBL
MVKMIKEYLKDKVLICDGAMGTYYSELTGNDVSYCEFGNLNDKDTIKRIHEEYIDAGAKL
IRTNTFSANTVTLGISRSELKEVLEAGINIAKEACKNKKVFIGASIGPIREENSENEDEI
ILEEYKFIIKCFLENDINIFIFETFSNPSHLKEISEYIKSKDPNSFILTQFAVKPDGFSR
DGISVNRIVQDIKDISQIDSYGFNCGSGPTFIYEIIKNLNLKGDIVSALPNAGYPMLIHE
RTVYTNSPDYFGKKVMEIKSLGVSIVGGCCGTKPSYIKNISSRIDEHIQEPAIEKNDIKG
HVDVVNKEENNFIKKLNNDEFVIAIELSAPMDTDISKLIEGAKICKNNGIDLVTIPDSPM
SRVRAESTIIASKIKREIGIDVMPHICCRDKNTNAIRSTLLGAHIEDIRNILAITGDPVS
DANKVETKSVFNLNSFKLIELMSDTNKEVFNGDDIYIGGALNLNVLNKEVEYNRMLKKIE
KGANFFLTQPIYDDDAIEFLRKIKEKTNVKILGGILPIVTYKNAQFLNNELPGVKIPQKY
INMFSLDMSKEEAEQVGINISVELGKKLKEVCDGLYFITPFKRVNMLMKIIHGINS
>A0A7X9FB10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSLFTPVRRWQPPFHPFKRQKFSLRLLAGIERMVKGPLFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGSTPDYCYVDKTRRCVWYLIYRRAFKRGREEKLMEVLPPLDWEKVGGETW
ADVTRQLRKTGTRKFFRGIVSRNPAVRHETWENLFRPVRQPDWWNGDAVYHPPAYHEPAS
SLEKKLRNGEFVFTTEVLPPLHSDISRLKQNIEAVKRFVSAVNFTDNSSAVPRMSGQSCC
KVAASLGADPVLQLTGRDNNRYSLQAKALGANMEGIRNILCITGDSPLIGSKPTGPMEMF
DLDAVQMLWILRRMRDDGKYLDGREIKYKPLYFLGAAASPFASKPKYQAWREHKKINAGA
QFLQTNLIFDIHGLEEWLEELYRRDILGKVFIIAGIAPLRSLRMAHHLRYEVPGVVVPDS
VIRRIEKAGVNAEEEGIQLALEMTQKISRMRGVHGIHLTTMGCESTVERIVRESGIVKDD
KNRL
>A0A0P1MZS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Chrysopegis kryptomonas|TrEMBL
MIKEQAEILIEAGVDLIILETFVSLNELDAAIEAVKEVSDKIPLIAQKTFPEDGAILATD
FPIEVVRHIKEKGVTVVGSNCTVGPQRMFSIIKAMYQDDVILSAQPAAGIPTLVDGRSVY
HASPEYLATYAKQLVEAGVKIIGACCGSTPSHIKAIASAVKDLKLKKAQIEIKIKKEEKQ
TQTNSTSDERISVVIEDKSSNFAKKIGKKFLTTVELDIPRGLDMSSVIEGARYLKENGID
AVNITDGARARFRMDPVTISHLVQSSVGIETITHIACRDRNLIGLQGLLLGAWALGIKNI
LAITGDPTKIGDFPNATTVLDVDSIGLIRILKNMNQGLDAVGNTIGEPTHFLIACAVNPT
AQNLDYEVSRLEKKVEAGAQIVFTQPLYEMKTLELFIKKIEHLKIPVMLGILPLRSYKHA
EFLHNEVPGINIPDWVREKLFLARDDAGKVGVEISAQFLKEAKHLVSGAYLLPPFKKYHL
AVEILQKI
>A0A7L6BYG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. RHBSTW-01013|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIAQDYWHNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A8D2IZG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Varanus komodoensis|TrEMBL
MRASPICVTPFLFFSLSSLAMVNESHSSSCGVAVAGDGVARFEGGGSSSGSESSKESSRC
STPVPDAERQAHLWEKMRQRQDAGDKWFSLEFFPPRTADGAVNLISRLDHMGAGGPLFID
ITWHPAGDPGSDKETSSMMMASTALNYCGLETVLHMTCCQQTREMITAHLQKAKRLGLRN
IMALRGGYPIGEEWQEEVGGFNYAVDLVKHIRNEFGDYFDVCVAGYPKGHPDAASYADDL
KHLKNKVSAGAGFVITQLFFRSETFLSFLKDCQAIGITCPIIPGIFPIQGYHSLRQLVKL
SKLEVPQEIRDVIEPIKDDDEAIRNYGIELAVCMCRKLLDSGQVHGLHFYTLNREVATTE
VLKRLGLWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGN
SSSPAFGELKDYYLFYLTSKCPRDELLKMWGEELTSEESVFEVFRCYITGEPNRNGHKVT
CLPWNDEPLAAETNLMQEELAKVNQRGILTINSQPNINGKPSTDRIVGWGPDGGYVFQKA
YLEFFTSSENVKALQTVLKRYGQRVNYHIVNVKGDNITNAHEMQPNAVTWGIFPSREIIQ
PTVVDPVSFMYWKDEAFALWIQQWAKLYQEESHSRKIIQDIHDSYYLVNLVDNEFPLDSC
LWQVLEDMHELLSGGAGQ
>A0A3G3JUH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella candidum|TrEMBL
MKPDLRTALQQKPLVGDGAMGTYLYELGFPVGVSYEEFNLLKPGIIGDVHRRYVDAGAVV
IETNTFSAQHGKLSKYGLEKKTEEINAAGVAIAREAAGDKAYVVGAMGAIRAGGRKNART
AGMKRDFEEQIGALLAAKPDGLLLETFFDLEELSLALSLIRARSDLPVICQFAVEDAART
HDGVPLGEAFRRLKAEGADVIGFNCRSGPNAILRAMETIPADLGAPLSVFPNAGIADLVD
GKVVYKATPEYFAQSAIRFADLGSRLIGGCCGTTPEHIAAIAQALNGYVPAAERPVRPET
SPSRIAVSETPASGGFTDVGEPSLVELVSRRHTVIVELDPPRDLDIARFMQGAKALKDAG
ADAVTMADNSLAVTRMSNMALGALVKERIGIRPLAHIACRDRNLIGTQSHMMGFDALGID
HVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGVAFSGKPLKQKAKFIVGAAFN
PNVKHLDKAVQRLERKVASGADYIMTQPVYDPALIERIAESTRHLGVPIFLGIMPLASGR
NAEYLHNEVPGIQLSDEVRARMNGLEGPAGRAEGVAIAQELLDAAMPHFNGIYLITPFLF
YDMTAALTEYVVRKGAAVSLRG
>A0A658KI57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. photiniae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>A0A357QHA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVINHIKNAQKTQFSFEILPPEKGANIQEIYDTIDPLMEFKPPYINVTYHKEEVVYKKH
PNGLLEPRTVKKRPGTVGISAAIKFKYDVIIVPHIICGGFSMEETENALIDLHFLGINNL
LVVRGDADKTTRSFVPDPNGHANAIDLIRQIKRMNDGKYVDDDLIATTPTDFSMGVAGYP
EKHNEAPNMDSDIRHLKAKVDAGADYIVTQMFFDNQKFYDFVKRCREAGITVPIIPGLKP
MSIKAHLNILPQTFHIDLPEILVKEIEKCETNAEVRQVGIEWGIMQSKDLIKNNVPIIHY
FTMGKSDNIRRIAEGAF
>A0A350YTD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSVIEKIRSAKSTLFTFELLPPLKGHSIERVYSTIDRLMEFSPAYINFTSHRNETVYRER
PDGLLEKRVVRKRPGTFALAAAVKYKYNIPVVPHVLCGGFTKEETENVLIEMNFLGIDDV
LALRGDPQKGSRSFIPEKEGHSHTWELVQQIVDMNNGKYLEESLQDTAPASFCIGVAGYP
EKHFEAPNRQVDLENLKLKVETGACYIVTQMFFDNRKFYRFRDECRSIGIDVPIIAGIKP
ISAVNDINLLPQTFHIDMPNDLVAALRKCKTDNEAREVGIEWAVQQSKDLIAEGVPGIHY
YTLGRSDNVARIVKAAF
>A0A6B9FPN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium mesophilicum SR1.6/6|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTDEMEKILWNSIERLAPLQPSFVSVTYGAGGSTR
ERTHNTVARMVRETGLKPAAHLTCVDASRDEIDAVVQSYWDAGVRHIVALRGDPAEGVGH
AYRPHPEGYASTAELVQGIKRIGDFKVSVSAYPEKHPEASSLEADIDALKAKVDAGADQA
ITQFFFENEIYLRYLEKVRAAGITIPIIPGILPVQNFKQAANFARRTGASVPYWLAARFE
GLEDDVETRRLVAGAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AAKAA
>A0A3Q8XZF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRAYMQRVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDQVVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRRPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A3D0HT50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MHIDEILTTTRKTLFSFEILPPLKGGTFEEIHQSIEPLLEFKPPYINVTYHQEEVVYKHR
DGGLLEKKIVRKRPGTVGIASALQYNCRVDVVPHIICGGFTREETENALIDLHFLGIHNV
LAVRGDPERSQKEFIAEPDGHTHAVDLVRQIIDLNHGRYLDEELQNSTATNFCVGVAGYP
EKHAEAPNQHSDLRHLKEKVDAGANYIVTQLFFDNSKFFDFVDRCRAAGITVPIVPGLKP
IAVKSHLIGLPKTFHIEIPDELVHLVEQCKSNREVRQVGVEWAITQTKDLIRAGVPAVHF
YTMGNPDNICQIARACF
>W3VFH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudozyma aphidis (strain ATCC 32657 / CBS 517.83 / DSM 70725 / JCM 10318 / NBRC 10182 / NRRL Y-7954 / St-0401)|TrEMBL
MANGIDTPSLPPKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMAD
LGPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPRDKIDTALKEAKEFG
CRNILALRGDPPAGQSEWEPHAAGFTQAQELVEYIRQQYGDYFAIAVAGFPEGHPEAVDG
PEKELERLKSKIDAGADFIFTQMFYDFDIFAKWVKDVRAAGITCPIIPGVMPIQTYGGFQ
RATARFGTLVPQYFHDALDPVKDDDQKVREIGTRLVGDMCKKIVGTGLGISGLHIYTMNL
EKGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRRDEKIRPIFWANRAKSYVNRTETWDEF
PNGRWGDARSPAYGDVDAYGVKLRYSNDEAKEMWGTPQSLDDVKALFQRFCAGQIKALPW
SETPVARETSVISEKLTKMNQLGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEF
FVSPEDLDALIARIEADVQITYHAVNAQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVE
SISFLAWKDEAYEIGRNWAKVYEPSSPSRKFLEAMFDNYFLVNVVHNDFKASDAIFEPFL
SAAKGAEAKGALSGLGASVSDAADKVSKAISSLANGGAANGHAATQTPAPAA
>A0A3R7SA24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium TMED241|TrEMBL
MTTALQRTLQAGNLAITAEVMPPRGGDASHTLAMADYLKGRVHAVNVTDGSRAVMRMSSL
AVCRLLLEKGLEPVLQLACRDRNRIALQGDLLGAHALGIHNLLCLTGDPVRAGDQADARP
VNEFESVKLLRQVSAFNSGEDPVQGTLADGATQLFAGCAADPQSRSWSGLQRRLQRKHDA
GARFVQTQMVMDAAALERFQRELAGPLQLPVLAGVFLLKSAKNARFINRVVPGACIPDDL
IARLEAAADPAMEGVAIAAEQVKRYLGIVQGVHLMAIKAEQRIPLILDQAGISISSLPG
>A0A1G6GDR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raineyella antarctica|TrEMBL
MSPRTIDELLRAGDRPLHSFEFFPPKTLEGDAMLWKALMELDELAPDFVSVTYGANGSRR
DMTVTITARLAQLMNERRARDPQARVMQVMGHLTCVNQPVDQLAEVIDEYAAAGIDHILA
IRGDMPGGPTVPWVRHPQGLENATELVRLVRRRHPRAVIGVAAFPDLHPDRRDAALDARI
LVEKQEAGASFAITQLFFEPYRYFELVERVRALGSDLPIIPGIQPVTNVGQIQRFAELSG
APLPDAVVARLTGVADDPEAVRRVGVDIGVELSRELLAGGAPGLHYYTLNRSRATREIYS
RLKAEVLQD
>A0A3D2HAZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MTVIELIKKAKGPLFTFELLPPLKGHSIERIYNTIDRLMEYQPAYINFTTHRNEIIYRDR
PDGLLEKRVVRLRPGTVALAAAVKYKYNITVVPHILCGGFTREETENVLIEMRFLGINDL
LALRGDPQKGSRVFIPEKNGHTHTWELVKQIADMNKGKYLEDTLENAEPSSFCIGVAGYP
EKHFEAPNKQVDMEHLKMKVDAGAHYIVTQMFFNNEHFYRFRNECREAGIDVPIIPGLKP
ISALNDINLLPQTFHVEIPNELVNVLKKCKTDEEARETGIDWATMQSKDLIKNGVPGIHY
YTLGRSDNIARIVKASF
>W3VI27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudozyma aphidis (strain ATCC 32657 / CBS 517.83 / DSM 70725 / JCM 10318 / NBRC 10182 / NRRL Y-7954 / St-0401)|TrEMBL
MAASSSSSTPGAHAAAAPHPVHITAKIQQANARDAPFWSFEFFPPKTTQGLANLYSRIAR
MRANLDPSWIHVTWGAGGTTVEKSLELAGRIQKGRLDPATPLLSADGRDSEASQQWQHEG
ADACDVCLHLTCTNVQKASLDQTLLAAKRLGIRNILALRGDPPRGEEYWVAADERFQHAT
DLVRYIRESHGDHFCIGVAGYPEGHADYVDRDVQRDLAFLKQKQDAGAQYIVTQLFYDVD
RFLAWYKDARAMGITIPILPGIMPIQNYQSFRRMTNLCKVQIPPLVLEALEPIKADDAAV
KEYGVALGIHMIGRIFLESDIRGFHLCSLNLEKSIERILDGLGWKTDVGALAEADVRLSA
VPAHLHLERTKNQMLSDRTGANTPRDFKVTTQEALKRTLARTSSSYQVPETTTWDEFPNG
RYGDSRSPAFGEMDGYGVSLKVPAADALRIWGHPVTLADISTIFASYLEEKIACIPWCDA
PLMHETLQIRDHLLALNRLGATPDAGKGWWSVGSQPAIDGAPSTDPVVGFGPSGGFIFQK
AFVELFMSASDKDALVEAIDAMGPHAQYTYFAGNARGDFVSNLAEGEANTVTWAVFPGKE
IVQSTIIERDSFEAWREEAFGIWNEWAMLFPKASASRQLIDGVTNDRWLVTIVHHDYKDA
QALWKFLAQ
>A0A7K4IH14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MLSHFQSLLERGDFVVTGEVGPPHGTDHSLVTERVRVVMDHCDAVNITDNVRGIPTMSSM
VCAHFVLRAGAEPIMQMSTRDRNRVLFQSDLYGAYALGVRNVMFVTGDHTLLGTHPQTKM
VYDIDSVQALQIASHLMTGRDLAGTELEGTPQLFIGATFNPYADPMEVQAWRVEKKQSAG
ARFFQTQAIYDTDRFRDFMGLIEGIDASVLAGIIPLKSAKMARFMNDRIPGIKIPSEVIE
RLECSGDGLHGDEKREAMKRTGITIALETIREVRSVKGVNGIHIMGVGWEDCIPELVRGS
GLYPRPVRGE
>A0A1H2G563|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas orientalis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVNVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQTEPSLAVWNNLKLPR
>A0A7V4E5I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus tengchongensis|TrEMBL
MKIRDLLKARKGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRERS
VLWAKRILGLKLNALAHLTVAGQSRKEVAEVLGRFVEVGVENILALRGDPPQGERVFRPH
PEGFRYASELVAHIRARYGEGLSVGGAAYPEGHPESTSLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRVGIEIPILPGIMPITSYTQLRRFTEVCGASIPGPLLSRLEKYQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGFRPWARTSEGV
>A0A662XT19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothophytophthora sp. Chile5|TrEMBL
MQLLLWHEALGSDDEQASEEELTARVLYSLDSSDELPPVGGGGREAVASVERLLQSLHFV
QGLLAFVRLLRRSRTAAQAPPAWTQEWISVTLSRRRFFVLEVEPLVFLALKDHRHAYEAL
LRDVYRLFRLFHGSIDRNLRLLPSVSSRPVTTATGDEKETESIPPHVKTHVDGMELLLDI
QTTRKRLRKLRLVIDAHTHNHPLDSSSQDEEGGDTVVGRLEAEQQTVEAELQALVARSPA
PQLQRKCVNFFPTLLQALDAGGASSFSELQGLGYFPMDQPLFLALQSFVNNLHTELKPTE
AGAEIAETSALFFKGNLLWSSMEISTMHLLYKFLRLREERGMELSGCGNQQSERSGARPP
AATEHTSALWMEDAYEDTFLPVWSSKLSYTDASTQQDLTGSAPEGPTMAILQRLEAHLDK
QQQFQMLAQRIFTRYHATFAPDMRYLHSLPPFLYLNRVNLAFKMQHVPRLLKTKEDELFP
LPTRLLAHYLPASTLALVNELHAELQAATSAGNRELCVRTRHAGWVLAKKSRTSRRELYV
LFDPKVSSVLDLSGAPPPIHPSDRLAAHSPIASAMGKIIDSVLSAYRAPEDDRPTISFEF
FPAKTNAGVFNLLTRVEEMGLALQPTFVTLTWRSAFTDEQLWLRIGAHIQNEFQLDVLLH
LTCHLPTQQLKQILHKARAAGIRNILALRGDPPIGADRWTPVEGGLSNAVDLIKLIRQEH
GDFFCIACAGYAEVHTEAWNHPELPPSNEARALDLQRLRAKQDAGADFIITQFFFDVDNM
VQWIADCKAAGISIPILPGYLPIQNYSSFCKFTSWCKTRVPADVLSALDAIKNDDAAVRR
YGTQLAVDTCRRLLAAGVRSLHFYTMNLAATVTQVMEGLELLPARNQRDLPWQSTLQRST
AEGEQVRPIFWSNRQASYIARTAAWDEFPNGRWGDRTSPAYGDLSEYYLAFKRPKLKRAD
LWGTPQTEQDVWSVFVRFIDGHVKQLPWCEQALSLESAAIRENLQWLNANGFLTINSQPR
VNGAPSSDLSVGWGGTNGVVFQKAYVEFFVAPEKLAHLVTVMRRDYPQLSFHALNRQGDE
HRNTPLHSVTAVTWGVFPGTEIVQPTVVDSDSFAAWKDEAFELWQTQWASAYPADSQARE
VVQHIHDSYFLVNIVDNDYANDDSDIFSIFTRIITEAMDKEHLRARVLQLEARREKMFET
LASFQALQEELGGELRAAHSELASARNTNLQLKEKVRQLQAQLALATL
>A0A8C6V3T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neogobius melanostomus|TrEMBL
MVNQVQRGDGTLSSRSDSSAASASGGDSSKESSRCSTPVLDADRTDRLRYKMRRRMESGD
HWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPSGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQSKDNISRHLSKAKHLGLKNIMALRGDPVGSDWEEEEEGFNYAVD
LVKHIRSEFDDYFDICVAGYPTGHPEAHSYKEDLIYLKEKVAAGADFVITQLFFRAETFL
KFEEDCRPSGSPCVCVQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIHQAL
EMCRVLLDSGRVPGLHFYTLNREVATMEVLRQLGMWQEDPRRPMPWAVSAHPKRKVEDVR
PIFWGSRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLVFEVF
TCYIAAQPNRKGHKVMCLPWNDEPLAPETNMLKDELEKVNTRGVLTINSQPNINGKPSTD
PIVGWGPPGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQ
PNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDN
YFLVNLVDNDFPLDSCLWQVSPPDTEGC
>A0A318ZCH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus saccharolyticus JOP 1030-1|TrEMBL
MHIKEKLSQNEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPVEKVDAALQAAYKAGCTNILALRGDPPREKEN
WEATDGGFRYAKDLVKHIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDNFIDWVKKCRDRGIAVPIIPGIMPIQTYAAFIRRSEWTKTRIPPEWLEAL
EPVKNDDAAVRNIGKRLVADMCRRLLKSGLNHLHFYTMNLAQSTQLVLEDLGLLPSEETP
LQRALPWRPSLGLNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGQPKSLRDVTHIFVDYLEGRLARLPWSDSPITAEANAIKDDLIE
LNKKGIFTINSQPAVNGVKSSHPVHGWGPKNGYVYQKAYLELLIPSYLLDDLIDRIEQNT
YLTYHAASKNGTLRTNTNDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQSIVDDWCLVNIVNNDFHNTSSLFDLFKDLNVKDLDTEIATEDGEIK
PQQNGVSNGAADGTVIDGTSTELPILN
>A0A0J8VAU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium swingsii|TrEMBL
MGYSHASHLDALNQNIVDLKGDLNVSFEFFPPSSEQMEKTLWASIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLIAAPHLTCIDASRDELRTIARDYWNSGIRDIVALRGD
LPPQGGRPDMYASDLVELLRKEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNMTQAKRFALANNVKIPGWLEKQYE
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAEVEIAA
P
>A0A0D0U2U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus gattii VGII Ram5|TrEMBL
MPHLTSLIATHNGPFHNYEFFPPLTDPGFVNLLDRIRRLTSPPFQAPLAVSVTWGAGGST
AERSLELAQQIVGMGVEVILHLTCTNMPKDKVDTALQRCKDLGISNILALRGDPPREEEY
AINPTSTPDFFKHADDLVRYIRQTHGDYFCIGVAGYPNPHPDSESEEEDFKWFKAKCDAG
ADFIVTQLFYDVDVFSEWVKTCRAKGINQPIIPGIMPIQNYASFRRLVNLTKCPVPDSIT
SDLQPISSDDAAVKRYGAELATKMVNQIIESGLVPGVHFCTLNLEKSVRTILDNLGWSAT
SKTSASDGVVKNKLIQDDSQAVNGIQINGKAGKTQNPAKDLSISPSEANQLAQLGLTSTT
LPPAPKTGLSAQGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKEWGVP
VSTSDLSALFTAYLHSDPNHLTTPFCDLPLSPESHMILPHLLALNSAKIQHWTVGSQPAV
DAAKSEDGVVGWGPRGGYVFQKAFVESFVTEDEVNRLTKKVEEEGKGLITMYAANRKGAF
RTNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWTEWSLLYPRNTPSRKL
LEGIANEWWLVSLIHHDYKDQDALWRFLLEDLQ
>A0A0M2LKR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter sp. Ag1|TrEMBL
MNATLLTGSAPTRARFSFEVFPARSGAAALALGHAVQHLSAAGPDFISVTYGANGSNRDA
SLDLLRYLRDHTDALPLAHLTTVGETREAVRATIHGIMDAGVHDFLALRGDPPRGSTEAD
PLVSGSLSALELTELIAEARAERPALTSVGRTAVAAYPNGHPMSRSRSEDLDWLVAKQEA
GAQFAITQLFFEAEEYLSFVSDARDAGLRIPVLPGLMPVSTSAQLRKVASLAGRPAPVLL
ERALEEAGGYAPELGVEHTIRLAGELLAGGAPSVHLYTFNRHEQVLAVLRELNLLAPVG
>A1UD70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. (strain KMS)|TrEMBL
MTSTDLQCPKRMQFGPCGGVRPDGQCEMRTGPCAFPDVVPWSGVEPASRPAQAPLVLTDF
SCAPFDEDDVAATARILGRSCDAVLVGEHQNRPDFPPTLMGRLLLEAGVTPWITLSCRDR
NRIVLEQELRGLRSLGVGTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGMVPAV
PETPTAPPVHARPARLVEKQRAGASLAVLNHVPYPDTITDFMATARTAGLSMPVVAAVAV
FTDVVSAAVLQGLPGLELDQSVVDEVLGAADPVSAGIAAAVAEARALLAIDGVDGVNVSG
LASASGTRVGAEIKAEVGRLVKAEVGA
>A0A2T7FXC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassorhabdomicrobium marinisediminis|TrEMBL
MPTPTVSFEFFPPKSLQASFRLWDCVQTLAPLGPEFVSVTYGAGGTTRKLTHEAVDALTN
ETDLAVAAHLTCVDASREETLAIADSYKKAGVSHIVALRGDPPKGTDAFQPDPNGFAGSI
ELTRALADRGFEVTVGAYPETHPDATDPRACIDHLKAKIDAGATRAITQFFFEGETFLRF
RDACADAGITAPILPGVLPVENWKGVQKFAASCGTQIPALVANGFAHSEKDGTSDLFATA
LATELCDELLCEGVEHLHFYTLNKPELTYDICRAVGLAPRSKLENVA
>A0A0Q5R6Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf357|TrEMBL
MVSVKDMQEARRALATPMFADVGGSDARVSFEFFPPKTEKMEETLWESVQTLSPLGPRFV
SVTYGAGGTTRERTHATVARIARDTNIPAAAHLTCVEATRKEIDAVANDYWEAGVRHIVA
LRGDPPVAGAKFQSPVGGYENAAALVAGLRKLHPFEISVAAYPECHPDSPDPVADLDNLK
RKLDAGASRAITQFFHEAETFFRYRDAVAKAGIDAEIVPGIMPIMNFGAVQRMSAMCGTV
VPSWMGTLFEGLDDHPAARQLVSATIAAELCRRLYAGGVRDFHFYTLNRAELSFAICHLL
GIRAKGVERAEAA
>A0A6S5I7F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas caviae|TrEMBL
MGFHSARQVEALNQSLADLGGDISVSFEFFPPNSEGMESTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLENDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQA
>A0A8I2K5S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MTKKEFLDRLKDSVMLFDGATGTMFYSHGIFINRCYDELNLSRPELVKEIHSSYVEAGAD
CIETNTFGANRVKLERHGFREKLAEINYEGAHLAREAAGPDVLVAGSIGPLGVKIEPWGP
MPKSEAREIFEEQARALKDGEVDLFILETFTTLSEIEQAITAVKEVCDLPVIASMSVRED
GNLMFGTQPESYIRALEEWNVDAVGLNCSVGPHHILETLETIVKLTDKPISAMPNAGLPR
SVEGRTIYMTSPEYMAEYVRRFIQIGVKIIGGCCGTTKAHIKAMRNAIASIIPQKQPTVR
KETRETVEKAQPIPLPERSMLGKKLAEGDFVTSVEITPPRGCEPIRVLESSKKLKENHVD
AVNIPDGPRALTRMSAQHLSILIQQQVGIETILHYTCRDRNLLGMMSDMLGLDAVGIKNL
LLITGDPPKMGDYPDATAVFDVDSIGLTNMVNNLNHGLDLGSNRIGKPTGYVIGVGLNPC
AVDVDTEIRRFEQKVKAGADFAITQPVFDVKGLMAFLEKITQFRIPIITGVWPLVSLRNA
EFMNNEVPGVSVPDEIMERMRATKSKEEALQEGINIACQMVRQIKDQVQGIQVSAPFGKV
KYALDVLAALR
>A0A7V5CZI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MRIEEWLALLQERVVLADGAMGTMLYNKGIYLNLCFDEVNLTSPDLVRSIHREYIQAGAE
IIETNTFGANRFKLKKYGLEDRVKEINRAGAIIAREEAGSRVWVAGSIGPLGVKIEPWGP
TSVEEAEEAFREQVRALLEGGVDLFILETFSDINEIHQAIKAVQKEAPDFLIVAQMTIEE
DGNSLYGTPPEVFTRKLEEWGAHVVGVNCSVGPAAMLQCLERMARVTSRPLSAMPNAGVP
RNVEGRNIYLCSPDYLAEYSRRFILTGARLVGGCCGTTPAHIRAIKGAIRSMQPARRPAV
FIREEVEEAVEVAPRPMAEKSALGKKLSEKQFVVSVEIVPPRGCDPSGAIEIARELKAKG
VDCVNIPDGPRASARMSSMALALLIQAQTGMEVILHYTCRDRNLLGIQSDLLGIHALGLR
NLLLITGDPPKLGDYPDATAVFDVDSIGLTNVVSFLNRGLDIGRRRLPVPTSFLIGVGVN
PGAINIDYELSRFHWKVEAGAEFAITQPVFDINLLERFLQRLESCRLPIIAGIWPLASLR
NAEFMHNEVPGARVPEEIMERMRRAQEISPERAREEGVAIAQEIVVRIKDMVQGIQISPP
SGRYDLALKVLEVL
>A0A6N2LPU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salix viminalis|TrEMBL
MKVIDKIRAAAAGGDANGSANGNGCDSSSNSKVVFSFEFFPPKTEDGVDNLFERMDRMVF
HNPSFCDITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDQALETIKSNG
IQNVLALRGDPPHGQDKFVQIQGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDMIGS
DGFATLEDYHKDLAYLKQKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMP
INNYKASYVPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKS
ALAILMSPRYKRTMAPPTNVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPHGRWGDSRNP
SYGALSDYQKFKVYCLGKLKSSPWSELDGLQPETKIINEHLGWGRPGGYVYQKAYLEFFC
SKDKLNAIVDKCKSFPFVTYIAVNKGGSWISNVALTDVNAVTWGLPSKGDYPANCCGSRQ
LQCVEGRGI
>A0A0K8MHY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructobacillus ficulneus|TrEMBL
MSLVEQFKKKTVFSLEVFPPKSNSGSKKIISTLEALNGVSPDFISVTLGAGGSAQSQETV
EVAKLIQNELHVPAVAHIPGLYRGTEDVDRLIEELLDNQINHVLALRGDPVAGLAPNGTF
DHAVDLIAYIQDKYPQVEIASACYPEVHSESKSVVEDINALRAKVAAGSQHLISQLFFDN
QHFYDFQERLALADIQVPVEAGIMPCTSKKQIERITAISGVPVPTKYRKMLDRYANNPAA
LKDAGIAYAIDQIIDLVAQGVDGIHLYTMNQPDVAERIWQATKSSFAANQKENLMVY
>A0A7C5DZ84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MKKPFLDFIKGNIALMDGAMGTEIYARGIFINTCYDELNLSNPKMIKEIHRSYIEAGADI
IETNTFGANRIKLQKHSLEDKVHTINYQGAEIAREMAGNKMYVAGSIGPLGERLEPWGIL
SEQEAREIYQEQAKPLLDGGVDIISLETFSDLHLIQQAIIGIKEKYGVPLMAHMTIGDDG
NSLFGTPPERLGVKMKEFGADIVGLNCSVGPKIMLDSIIRMIAAVDIPVSVMLNAGIPQN
VDGRNIYLATAEYFGEYARRFAQAGVQVIGSCCGTNAEFTKEMQKAIQSIRPRKRIKVRP
QAVSEKELKPEIPTYQRSEMARKIHENEFITSVEIIPPRGIDHSNALERAKALKQAGVDA
VNIPDGPRALSRMSSSYLSLAIQEKIGLEVIQHYACRDRNLLGMVGDLLGAYSAGIKNIL
LITGDPPKMGTY
>A0A2K8ZVL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. HBCD-sjtu|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVAEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNATPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7J9Z8N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangiales bacterium|TrEMBL
MRNSVLVRPTVLTGLLAAPRYEIIPTAAAEEAIRAHVPLDVSVAVTASPTKGLGPTVDVA
TRLALAGYHVVPHLSARLVEDDVHLADLVARLREANVSDVFVPAGDADPPVGEFTAALDV
LRRLTDLGRPFRQVGITGYPESHPTLSDDIVVQAMWDKRGHATYVVSNLCFDHTVVARWV
KRMRARGVGLPLYLGVAGPVERAKLVSMAAKIGVGESTRFLGKHPSWFLRMAGPGGYSPE
RYLRRTTTALARQQTPVAGLHIFTFNQVAETERWRQRLLAEAQH
>A0A8I2G374|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
IQTQGIYDIELFRSQMGKICNMGLHERTALLGGIIVPKSAMMLKYMDASVAGVTVPNPLI
ERMNRAKEAAGGDKKKAREL
>A0A3A8Z011|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium 1xD8-6|TrEMBL
MTIQEYLKERPLLFDGAMGTYLAERCPELGEMHCERANITHPSLVKEIHREYLLAGAAAI
KTNTFAANCQMMEEGMPAVSDLIRAGWELASQAAQEEAGTHFVFADIGPVPVKDGQELYD
AYREIADVFLSCGARCFLFETMGSAEALAEISAYIKERAGDSFVMVSFAASPEGYTRSGF
LVKKLFWQMQQCDTVDAVGFNCISGPKHLLEQIRSLPPAGACKYLTVMPNAGYPTMLGNR
IHYGADREYFGQNAIELLEAGASIVGGCCGTAPEDIESIASRLTREFIDGIYKRQRASVI
SSGQESGRPPGKRVLAKESGEDGSSISGMDNGRNAFAEKLRGGRKVIVVELDPPVEPDID
FFMEGAARYKYAGVDAVDIADCPIAKARIDSSVLACKLSRELGITAIPHMTCRDRNINAT
KALLLGLNIEGVNNVLTVTGDPVPTAMRSQIKTVFSYNSAILARHIQSFNQEIFAENPFM
VSGALNINALNFDSQILHAKRKIESGVSVLFTQPVLSERGLGNLRRARKELPAKILGGIM
PVVSFRNAAFMNNEMAGIEIDKEIMEKYRDKNREEGEELAYRISVGIIDKISGSVDGFYV
ITPFKRVELILRIVGYIKSVYGK
>B7KBZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gloeothece citriformis (strain PCC 7424)|TrEMBL
MTKIMFNNFRRAIQAKEFLITAEVTPPKGSNPARMLEMAKCLKGRVHAVNVTDGSRAVLR
MSSLAASAILLHHEIEPICQMACRDRNAIALQGDLMGAYALGIRNILALTGDPVKAGDHK
KAKAVFELESVRLLKVIDKLNQGFDFNDQPLPDDPLDLFAGAAVDPQLKSTSGLKKRFEH
KIEAGAKFFQSQLITDFDLLDKFMHQVAAGYDKPVLAGIFLLKSAKNAAFINRNVPGVHI
PDEIIKRLAEAKDPLFEGVKIAAEQVKMAQKLCQGVHLMAIKREDLIPQILDLAGIAPID
>A0A1C1YW09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea olei|TrEMBL
MSQADTNPHDPGGLLEPLPGHSSRGRLERILRRGEFAVTAELNPPDSANPHDVYERAAIF
DGWVDGINAVDASGANAHMSSVGICALLTRMGYAPIMQISCRDKNRIAIQGDVLGASAMG
VQNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRIMRDNSKFLSGRKLTSPPNVFLGA
AINPFAPPHDFRPYRLAKKIAAGAQFVQSQYCYDVPMFRDYMSRVRDMGLHKDCFILCGV
GPLASARTARWMRSNVPGVHIPDEVIKRLEGAEDQKKEGKQICIDIINEVKEIEGVAGIH
VMAYRQEEYVAEIVHESGVLKGRRPWRKEPNPADELVAARMEEILEEPRQIPHELAGAAT
DSEAAG
>Q7NZF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)|TrEMBL
MTQTPRTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
HSEGQAAAPHLSCIGSTRENIAAILNEYRGNGIRHLVALRGDIPSGMVAAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLANFVRKVRAGADSAMTQYFFNADSYFRF
VDEVRARGVDIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRLRMQSYYDDTASIRALGL
DVVTELCDRLLQGGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A0E1SNI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae PittII|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A1S7P4G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium tumefaciens str. CFBP 5621|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNAEMETQLWETVAELKKWDPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLSTAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYQ
PHPEGYENAAALVKGLRDIGDFEISVSAYPEKHPESASDAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A286RFC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermogutta terrifontis|TrEMBL
MTGGATAEPSGLSFRRLLESGGFPIGVEIVSTRGFPANPGDAPPIILARELLSHPRIGWI
SITDNPGGNPMLPADWIAQFLFNERDRIVIHMTCKDTNRAGLESLAWRLAAEGLHNVLAL
TGDYPTAGFGGKPQGVFDLDSVGLIALLKAMNEGLSVTTRPGKRETLPPTRFYIGCAVSP
FKRYERELVPQYFKLVRKIATGAEWVITQLGYDMRKYHEVKLFLQARGISGIPAIGNVYL
LTKTVAKLFHDRQLPGCVVTDELWELCQKYAAGPDRGKKFFAELAAKQLAVLRGLGFAAG
YLGGIHKLESLEEVLRHLDSFAPDDWRQFLKEIQFSFPDEFFFFEHEPETGLSGPEKINR
QYLESLRKPRRSRYVTLGYRLSRLVHRLAFTRGKGLWNLAQRLYQRWAGKPRPPAPARVL
YGLEKFSKYVMYGCQDCGDCSLPDCAYICPKRWCSKCSRNGPCGGSVDGECELRNKECLW
AIVYERLKAYGESEEMLSGPPVLYNAELAHTSSWANTYLNRDHHGVTEKRDLGQDTSGGA
NTHGE
>A0A662K039|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
EIGVNYAVKQCRELMDKVPCIHFYTMDRWASVDRILKELI
>A0A810DXR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. URB8-2|TrEMBL
MKPDLRSAWASKVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEEVHRSYIEAGAEL
LESNTYSANYDKLSKFGLESKVEEINRAGIRIARQAAGSGGYVVGAVGSIRAGKRASLSA
SELKKYFGQQIGAMLEEDVDGIILETFYDLEELHLALRTARKLSNLPVICQFAVDETAMT
MDGLTLPEAFRILEEDGADIIGFNCRTGPIGIKRALGTLQGSLTLPVSVYPNAGLADYVD
GHYKYGASPEYFGQMARDFADMGSRIIGGCCGTTPHHIAEISAALKGYEPLPLPGPAPKE
KISVRLQESLADDSAADGREPNLIDIVKERHAVIVELDPPRDLDISKFMAGAEALRRAGA
DALTLADNSLAVCRMSNMALGSLVQQRTGLRPLVHIACRDRNLIGTQSHLMGLDALDIDH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKANFIIGAAFNP
NVKHLGKAVERLEKKIAFGADYIMTQPVYDRELIHKIADATAHLNIPIFIGIMPLASGRN
AEYLHNEVPGIQLSEEVLGRMKGLQGEVGRAEGVAIAKELLDAATERFNGIYLMTPFMFY
DMSAQLLNHVWAKSGRQLSPLFR
>A0A857J927|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylophilus rhododendri|TrEMBL
MSVDVSPARSAAVPVSFEFFPPKTPEGVAKLRAVRQALYARRPEFCSVTYGAGGSTQEGT
FGTVREILAEGMDAASHFSCIGATRESIRGQLQELRAMGVKRLVALRGDLPSGYGAGGEF
SYASDLVEFIRAETGDAFHIEVAAYPETHPQARSPEADLQAFVAKAKAGADTAITQYFYN
ADAYFRFVDDARARGVDIPVVPGIMPITNSTQLLRFSDASGAEIPRWIRLRLQAFGDDSE
GIRAFGLDVVAGLCRRLLDGGAPGLHLYTMNQSAASLALLDRVGLGA
>A0A7Z2Y8I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. SB49|TrEMBL
MNLREALQNKTLIGDGAMGTLLYSYGIDRCFEELNLSHSEEVLNVHRAYVNAGADVIQTN
TYGANYIKLTRYGLQEQVKEINTAAVRLAKQAAHEGTYVVGTIGGIRGVQKQSFSLEEIK
RSFREQLYCLLFEEVDGLLLETYYDLEELKAVLEIARKETDLPIIAQVSMHEAGVLQEGT
SLSDALQQLEQQGADIIGVNCRLGPYHMIQSLEDVPLPDKAVLSAYPNASLPAFQDGRLV
YATDPNYFEKSAKSLYQQGARLIGGCCGTTPEHIEAIAAAVKGKEPIRKKEVPVKQGNGV
SLSSPEKNLEHLHERAKRGRSIIVELDPPKKLNTDKFLEGAKALQDAGVDSITLADNSLA
SPRISNDTMASIIKTKYGVDPLVHIACRDRNLIGLQSHLMGLHTLGIQQLLAVTGDPTKI
GDFPGATSVYDLSSFDLIHYIKQLNKGISFSGKSLGERTSFSVAAAFNPNVRNLNRAVGR
MEKKMKYGADYFISQPVFNHEQIVEVYEATKHIEAPIYIGIMPLTSARNAEFLHNEVPGI
QLSPEILARMEQAGTDKTQAQAEGISIAKSLIDTAMDLFNGIYLITPFLRYEMTVELTNY
IKEKTAQRERKVTDGIHLV
>A0A852T7L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neobacillus niacini|TrEMBL
MSFLEKLKNQILIGDGAMGTLLYSFGKDSCLEELNLSHPEKIQEIHKAYIEAGADVIQTN
TYAANYLKLQRYGLEDSVKAINSAAVQNAKLAAQENAYVLGTVGGNRGIKPSTLSIEELK
RSFREQLYCLLLEGVDGILLETFYDLEELETVLAIARKETKLPIIAQVSLHEPGILQDQT
PINEAFTRLENLGADVIGLNCRLGPHHMLKSLEQIELPKHAYLSAYPNASLPAYTDGKFH
YEGDADYFKKSAQSFRQEGVHLLGGCCGTTPAHIQAFSAELKNSVPVTEKVVKLQSKKIV
IEHSTAKRDLQPLEQIVKERPSVIVELDTPRKLDTSKFFEGAKALKEAGIDAITMADNSL
AQVRISNEALGYLVKQELGMRPLIHIACRDRNIIGLQSHLMGLHTLGMHDVLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTAFSIAGAFNPNVRSVEKAVK
RLEKKIEFGADYFISQPVFSEEKIIEVYEHTKHLKAPIYIGLMPLTGSRNAEFLHNEVPG
IKIAQSIRDRMAALNDNPLQAAREGIEITKSLIDTALDLFNGIYLITPFLRYELTTELAI
YARQRASQIRGNSYVESTI
>A0A2G2JV97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leeuwenhoekiella sp|TrEMBL
DCHYLGIHNVMALRGDAMKEQQYFEPTKGGHEYALGLVEQIADMNKGRYLNNVIETSDCS
DFCIGVAGYPEKHLEAPSLKTDLKRLIQKVEAGADYVVTQMFFDNKKYFEFVDMVRAEGI
DIPIIPGIKPIAVKRHLQLLPQVFKIDLPQELIDAVESCKSNQDVRQVGIEWAIQQSREL
MEGGAPVLHYYSMGKSDNIQAIAAELF
>A0A0G2FRS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diaporthe ampelina|TrEMBL
MDKITDKVAALPPDANYFSLEFFPPKTQMGFANLRSRLERMARALKPTFVNVTWGAGGST
AQKSMELAEICQRELGLTTCLHLTCTNMSRRLIDKALEDAKVLGIRNILALRGDPPRKEE
YRDENEDDDDGEDEFTWAVDLVRYIRKNHGDHFCIGVAAYPEGHADESHPLGQSMEHDLS
SLVEKVQAGADFIMTQLFFDIKAYDKFEKVLREHPSGAFKDTIIIPGLMPIQNYQMIKRT
TKLSHARIPDDLMARLEDVKKDDEQVKQVGVDILSELVEQIREIKSRTPGPKGFHFYTLN
LEKAVSFILERTDLIPPETRSEQAVIDDLITLVPKIEVNGSGSNHSSQQHLAIGHSSRRQ
SNVSSEPRNRVIMSGENRNPSNPEYEATQLEASRPFDPVHSRVNTLAISEGEGILGREAT
WDDFPNGRWGDARSPAYGEIDGYGVSLHMSVTQAQRLWGAPKAVEDINTLFIRHLKGELS
AIPWSEEEFNAETGTIKERLIELNSRGWWTVASQPAVNGLRSSDPTFGWGPANGFVFQKT
FVEFFCPADDWKRLYEKLSRPEMKDSIWFYAANAVGDFLSSDFSGGLDLEMKEAGTNAVT
WGVFPGKEIITPTIIEEVSFRAWAEEAFGIWGEWAQVYGKGSESSKFLEQMKNGLWLVNI
IHHEYVEKDALWDLLASS
>W0T9G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyveromyces marxianus (strain DMKU3-1042 / BCC 29191 / NBRC 104275)|TrEMBL
MRISQKLQRAHEDSNQDATFSFEFFVPKTAQGVQNLYERMDRMYQTQPEFIDITWNAGGR
LSMLSTDLVATSQGVLGLETCMHLTCTNMPVSQIDEALQKAYDAGCQNILALRGDPPINS
LGEEEEWKPCENGFRYAKDLVSYIREKYGDHFDVGVAAYPEGHPECESESDLLQHLKEKV
DCGADFMITQMFYDVDKFLDWCAKVRAAGISIPIIPGIMPITSYPAFIRRTQWCQINVPE
KFIAKLEPVKDDDQLVRELGTELMVELCTRLLESGYVNHLHLYTMNLEKASLMILERLGL
LKSSASARSSTSSSSGSHSIEEPLEPLPWRKSLNPKRKNELVRPIFWQKRPYSYVARTSL
WNEDEFPNGRFGDSSSPAYGDLDLCGHSLIRQSVKKSIELWSTPSNLDDISSLIISYLEG
KLKCLPWSDVPLNHEVDDILLGLIDINKHHIFTINSQPKVNGKPSTDPVVGWGPTKGYVY
QKQYLEFLLPRDKLPRFQELCSKHDDHLTYFAIDANDDLSTNHPEETRANAVTWGVFPGS
EILQPTIVEKVSFLAWKEEFYTILKEWKLTFQEHKAAQSINLVNELIDNYVLVNVVDNDF
ISPNNHIFDVLQQLY
>F9PE94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus infantis X|TrEMBL
MSRQTPSLSFEVFPPNPEVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDEVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFINEQAPHFDIVGACYPEGHPDSPNQISDIQNLKRKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLRTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQP
>A0A0U3AWC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacimicrobium alkaliphilum|TrEMBL
MVSYAQGIDALNNSLSELRNIDVSFEFFPPKTEQMERTLWNSVERLAPLKPAYMSVTYGA
NSGERDRTHEVVKRIQAETGVAAAPHLTCVDASREELIQIAKDYWAADIKKIVALRGDLP
PGVAQTELYAADLVALLKDVADFDIAVAAYPEIHPEAPNGQFDLLNLKRKAEAGATSAIT
QFFFDAEVFLRFRDRAAAAGIDMEIIPGILPVTNYKTLVKFAGMTNVHVPQWLHKMYEGL
DEADQTTRNLLGASIAMDMTRILAKEGVRNFHFYTLNRCELSYAICHMLGLRANSG
>A0A1I2IUA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nannocystis exedens|TrEMBL
MYQTARRWTRTLGPCYEDGDMLIRERLAHKRPVFSFEFFPPKTEKGEAVLWRSLEQLAPL
SPDFVSVTYGAGGSTRTRTLDIVARIKRELGIEPMAHLTCVGATRDELARTIDQLGDREI
CNILALRGDPPKGEAAFVAPEGGLRHASELVAFIRERGPFCIGAACYPEVHPEAESGATD
LKWLKHKVDAGVDFLISQLFFDNATYHDFVGRAIEAGITVPILAGVMPVTNYEQIQRFTQ
MCGATIPAPLRQRLQSTEGDPQEVFWTGVSYAAHQCRALLTPPVGDPFATPRPGVPGIHF
YTLNKSPATRAIFEILRLAHVAV
>Q47JN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dechloromonas aromatica (strain RCB)|TrEMBL
MKPEISIEFFPPQTPEGIEKLRTVRAELAKLNPHFFSVTYGAGGSTRERTFAVVKEIAAE
GFDAAPHLSCIGSTRESIREILAEYKSAGIKRTVALRGDLPSGMAEAGEFRYANELVEFI
RAETGDWFSIEVAAYPEWHPQARSPKDDLEAFARKVKAGANSAITQYFYNADAYFHFVDE
AKALGVDVPIIPGIMPIAGFTKLARFSDACGADIPRWMRKKFESFGDDADSIRAFGLDVV
TELCERLLKGGAPGLHFYAMNQSALTTEICRRLG
>A0A147EFG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium barchaimii|TrEMBL
MTDVIEAERSANPAANASPYSDLPGDIAVSFEFFPPKTEKMDSQLWEAIGDLAPLVPSFV
SVTYGAGGSTRERTHATVSRIVRETNLKPAAHLTCVAASKGEIGEIADQYWDAGVRHIVA
LRGDPPPADGGRFVPHPDGYASAAELVAGLKARHDFEISVAAYPEVHPEATSAAHDLDNL
KRKLDAGANRAITQFFYSTDAYFRFLDKALAAGIDAPILPGIMPVTNFAAIRRMSGNTEI
PPALETLFEGLEDRPGPRALVAAVAAADLCRRLYDGGVRDFHFYTLNRAEQTYAVCQLLG
VRPTENA
>A0A074J6U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioclava indica|TrEMBL
MTTPRISFEFFPPQTLDASFRLWETAQVLAPLQPEFVSVTYGAGGTTRKLTHEAVGAIHK
NYGLNVAAHLTCVEATKAETMEIVNAYADVGVTEIVALRGDPPKGSAGFTPHPDGFASSV
ELIEALAEDGRFTIRCGAYPEPHPEATDSLADVRWLKRKVEAGATSAITQFFFEADTFFR
FRDACVKEGIEAKIIPGILPIQSWKGAKKFAQSCGTSIPAWVEEAFEAATRDDREQLLAT
ALCTELCDKLIEGGVEDLQFYTLNRPTLTRDVCHALGVTPETVLENVA
>A0A1J5FJ10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacteraceae bacterium CG2_30_36_10|TrEMBL
MFDKLLDKLKNDTYLSLETTPGHSPVFSPIINKIEELGLDKLVDAFSTTDNPLAKLKYNA
LFAAKMLQERFHKPVLATMSMRDRNKIALQSDLLGANEVNIRAILALTGDPATISDQPHT
KGVFESDSSMLLDMISCFNSGIDYAGKPLAQKPQEIFPFAVVNAYSKNPKTLQKKMQKKI
KHGACGIITQPVYDLESAKILVDLMEAANKECALESNAQLILGIFPITKLRTAQFLATNV
PGINVPNKWIEALKSANERGVEEEYKVGFELSKKLFDDIKALHPKIHLMTANQFQIAKDI
LV
>A0A2M7KAH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium CG_4_8_14_3_um_filter_34_18|TrEMBL
MNLREKLAAKKFVVTVELDPPKTLNLDKILREINSANFRKVVDAVNVTDCPLAKLRMSPI
ALSHIIQEKIGLESIFHITCRDRNLLGLQAELLGASALGVKNILALTGDPPEMGDYTKAT
GVYDLDSVGLVKMVNKLNNGYEYKGEELKSRTDFFIGVAVNPSAQDLKKEIKRFEEKVSA
GANFVQTQPIYDIEILERFLEFTAHLNIPKIIGIMPLKSYKMIEYLNNNLPEIFIPSVVK
ERMIGKDIGEGIKISQEFIDKIRKFKEVAGIHIFPLRDMDLVCRLLN
>A0A1M6HM89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hespellia stercorisuis DSM 15480|TrEMBL
MKIIEKLNDGKVHISFEVFPPKKSEDFDKVMGAAKKIAGLHPSYMSVTYGAGGGTSKNTV
KIASQIKEECNVEALAHLTCASSTKEEVRKVIGQLRDAGIENVLALRGDIVEEMAFPSED
RFHYASELVEEVKKSGDFCIGAACYPEGHVEAEHKEEDILHLKHKVDCGVDFLTTQMFFD
NNIHYNFLYRIREKGITVPVIPGIMPVTNGNQMARIVQMSGTILPARFRAIIDTFGENPA
AMRQAGIAYATDQIIDLIANGIKNIHVYSMNKPEVAAAIISNLSDIIKE
>A0A1E7HBN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium S3730MH12|TrEMBL
MDAADQNSNSTNSYSLIAEIDPPKGANLAGFLDTALKVRGRVDSVRVTDSEHAIMRMSPI
APCLALLDKTIDPIMIITGRDRNRISFQADLLSAAALGIKKIVIKEGHDPAEGDQPVART
SGDLDLVSMLQCAAALNSGKDLAGESLDGGTDFEIGVSVELSDDVNFNRERAEFFMQLGD
YGVTSVTLGPTYDINIVEQFVPFAEKTGIKLYSSLMFLKSVTMIRYLNNLTGAPSIPQEF
LKKMMQAPVKKDAGMQVAADFMEELSTLGDGIVLLAIGWKGRLPEFLDLIDR
>A0A1H0Z233|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. khp1|TrEMBL
MSVTEFIHQDKEAKRFSFEVLPPLKGTGTAKLFADIDKLREFDPAYINITTHHSEFVYHE
LENGQFERRRIRRRPGTIAIAAAIQQRYQIPVQPHVICSGATIEDIEYELLDLQFLGIND
LLLLRGDKAKEDSRFQPTPGGHAHTTDLMAQVKRFNEGFFADGTPIKNPGRPFDYGVACY
PEKHEEAPNLEMDMQYLKQKQDLGAQYAVTQLFFDNEKYYAFVEKARQMGITIPIIPGIK
PMAKLSQLTVVPKTFHCDIPEPLAKEVVKCKTDEDAKQLGIEWTTQQCKDLYAHGVHNIH
FYTVSAVDSVAEIVKRLVVRG
>A0A4R6ARD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Palleronia sediminis|TrEMBL
MTRISFEFFPPKSLEASFRLWDTIHSLAPLAPDFVSVTYGAGGTTRKLTHEAVTTINKAT
GLRVAAHLTCVDASRAETLEIAESYSQAGITDLVALRGDMPGGGAFRRHEDGFANSIELI
EALAATGKFTLRVGAYPDGHPESASAEANVEWLKRKIDAGAQSAITQFFFETESFLRFRD
RCVAAGITAPIVPGILPIENWKGVRKFAESCGTPIPAWVEDAFAKAERDDRSDLLATSLC
TEMCSDLLAEGVGDLHFYTLNKPNLTRDVVFALGLAPEPALQHVA
>A0A7W5X5T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK602|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMG
VQNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTSPPRVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLHEKCFILVGV
GPLASARTARWMRSNVPGVHIPDDIIKRIEGAEDQKKEGKQLCIDIINEVKDIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRRPWKHEASRTDALVAERLEHIREGKEENQQEMAEAAA
HHPPPQTH
>A0A3S3UEB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electrothrix marina|TrEMBL
MKSGSNLERVLRSGAFAVTGELGPPKNSDPDVVREKARILKGNVDAVNITDCQTAIVRMS
SIGAGLLAQAEGVEPVIQMTCRDRNRIGMQSDLLAASALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMVRDMRDGKKFQCGEEIKGKGTELFLGAAANPFAYPHEFRAVRMGKK
IANGADFIQTQIIYNLDRFAEFMKKACELGLHEKAYILAGVTPPKSVGMARYMKKFVPGM
DVTDEVIKRMQGAKDKKQEGINICVDIINQVKEIPGVAGVHVMAIEWEEAVPEICEKAGL
LPRPTFDVFGEPALAFEATGEKAAEAIEVRGADEDQDAADDILEQAKAEAEKIIAAARTQ
AAAFAGQTAQSGQATTENAAVSGQAADDAGEHAMNEKGRRAALESVNQGLNALKKAYGLS
DDQFDALMNFVDAASVLNKEPE
>F7X402|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium meliloti (strain SM11)|TrEMBL
MNGRTPYPVDCDGLRFSFEYFPPKNDEMETQLFQTVTALSVFAPAFVTVTYGAGGSTKAR
SLTTVKRMIGEMEIANTAAHLTCVGAPKAEVDAVIDEFLACGVRHFVALRGDPQGGIGSV
YEPFPGGYENAAALVKALRARGDFEISVSAYPEKHPESPDVAADIDMLKRKVDNGATRAL
TQFFFDNDDFERYLERVRRAGIAIPIVPGILPINNLTQVQKFAGLCGARVPESIVSRLGP
IDDQPEERFREAAHIAAEQVADLVRRGVSDFHLYTMNRPQLITAVCELMGYDPEIAPAQP
ADTERSVRAVARA
>A0A4R1MYW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natranaerovirga hydrolytica|TrEMBL
MNLKHYLQNNILITDGAMGTYYAQVTQSNNTLSEKANIHQPDIIYNIHKEYIEAGAKLIR
TNTFSANTKVLEQDIKGVKEIIKKAYALAQQAVSDAKEDVVIASSIGPIPDKDFLEEEDL
FEEYKAIVDTFLKVGADTFIFETFSDINYLQDIVPYIKSKNKNATVITEFALNIYGYTKK
GKSANRLLDDLRKIEDIDLYGFNCGIGAGHLYQIMQKVRWSDNEILTAMPNSGYPDVLQD
RTVYMDNTDYFVDTMIDLAKLGVKVIGGCCGTTPMHIQKLNEALKDFSMETIRRPRKVEA
AVSTKAKKINALEKKFTTNEPVIAVELDPPFGQKIDKMMEAANLLKANDVDIITIADSPM
GKPRADALIVASKVSREVGIPVMPHICCRDKNVIGLKAQILGGYIEGIRDLLLVTGDPIP
SGDRNEIKSVFNLNSITLMEMLREMNIEHFEDEPIFYGGALNPNRANIDKEIERMQKKID
AGAKFFLTQPIYDEATIEKIKYIKSKVDTKILGGVLPLVNIRNARFIQNEIIGITVPDEV
IHQFDEKMTREESEKIGIEIGKKVALKMKNIVDGFYFMVPFNRVNMINEIIKALKKG
>A0A7G9BLI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olivibacter sp. SDN3|TrEMBL
MKITEHIASAKGKPLFSFELLPPIKGQSIQGIFNTIDPLMEFNPPFIDVTYLREDYIYKQ
HPSGLLEKVAYRKRPSTVATCAAIMNRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARKSDSTFIPTPGGHAYATELLEHVVNMNNGVYLHDMMEGSEKTDFCIGVAGY
PEKHFESPNLETDFKYLKRKVELGANFIVTQMFFDNNKYRIFVEKCKKHGINVPIIPGLK
PITTRKQLVSLPKVFHLDIPLELSEAIEACKNPKDVKEVGIEWMIHQCKELIKLGAPVLH
FYTMGNPEPTKRIIQGVF
>A0A4U0YS45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cereibacter changlensis|TrEMBL
MTQPRISFEFFPPQTLDASFRLWETVQMLAPLKPSFASVTYGAGGTTRKLTHEAVTTIGR
NYGLNVAAHLTCVDATRAETLEIAAAYAEAGVTEIVALRGDAPKGAERFTAHPEGFANSI
ELIEALAATGKFTLRVGAYPEPHPEATDPLADVRWLKRKIEAGASSAITQFFFEAETFLR
FRDACVAEGITAPIIPGILPIENWAGVKKFAQRCGTAVPQWLDDAFDHAKRDGREDLLSV
ALCTELCDTLLSEGVEDLHFYTLNRPHLTREVCHALGVAPEVALQNVA
>A0A4U9TGA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia fonticola|TrEMBL
MTQRAGAKLDDQHVCRAGMTMRKTRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSY
AICHTLGVRPSAVVG
>A0A4Q5LLY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter terrigena|TrEMBL
MKITEHIANANGKTLFSFELIPPLKGQSIQGIYDAIDPLMEFKPPFIDVTSLREDYIYKE
HETGLLEKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLQFLGIDN
VLVLRGDARRGDASFVPTPNGHCYATDLLQQVVNMNNGVYLHEHYEGILKTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGAGFIVTQMFFDNQKYFDFVNNCRAEGINVPIIPGLK
PITTSKQLVNLSKTFHIDIPETLSDAIHDCKDEKNVKDIGIEWMIEQCKELVKFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A1L3Z5L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MALKNEARGRNDIRVSFEFFPPKSEEMEGQLWHAVSQLQDWDPDFVSVTYGAGGTTKAPT
LSTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQ
PHPGGYANAAELVAGLKEVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQ
FFFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFD
DKPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLENLGLSRRQTKSAGAA
A
>A0A354CIG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
MMESLREYLKGHRLITDGAMGTYYSEITNNPEAFAEFANIERPDIIERIHNEYIDAGAKL
IRTNTFAANTQMLGIGRDELKKLIEDACRIAQRCADGRAYVAGDIGPIKENAESEGSAVE
EYKMICDIFLDMKVDAIRFETFADFDDIKEVAEYVRSKSDMFIMADFCLNKNGFTAGGIS
AARIMQQAGQMDCIDSCGFNCGIGSGHMNNIMQKLTFAKDKYMSCLPNAGYPEQMNNRMV
FMNNASYFCDNMQKISAYGMNIIGGCCGTKPAYIRELCRRIGDAVPAGRTETSDGNEPVN
GNNPAEAADIRVNEKRPNEFMQLFKSGHKVVAVELDPPYDAKYDRLIEQAQYLKSRGVDI
LTFADSPMGRSRVDSVLMSLKVTQETGMMVMPHVCCRDKNVIAMRSTLLGAYINGIRQLL
LVTGDPVPSVSRVSTTGVFDYNSIRLMNFVKEMNQEHFADEPLYYGGALNVTLGRIDRIM
ERMQKKIDNGASYFMTQPVFSKEGIERLAMIKEKMDTKILCGIMPLVSYRNANFIKNEFI
GIDVPDEIVARYSPDMSKEEGEAVGAQIANELIGQMYDYVDGFYFMLPFNRVSLMDKINI
NNR
>A0A838AZ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium neociceri|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVVREFAEMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHEAEAA
GSAAA
>A0A1G0JTM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPLOWO2_02_FULL_56_15|TrEMBL
MLNRLLAGQDIHGQEVDRKRAMAGLIVKSSIEVTTLDHDKIQQARELLPKNMNVYLPSLP
NQTLMSKLGCVATLRDAGFEPVPHLAARRIPTRQELESFLKQAVQQHQVDHILLVGGDVP
EAAGPYSEAAMILKEGILAENGIRLVGLPAFPEGHPRVSSAVMQAALDEKIKLAREAGHE
VHLVTQFSFAPDRVTTYCEMLSHRYPGMPVYVGLSGPTNPAQLLRYAKLC
>A0A2E2XA31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea sp|TrEMBL
MPTRFDSPTLAGRIKVSFEFFPPKNGDMEGQLWESISRLAPFNPDFVSVTYGAGGSTKQP
TLNTISRIIGETDLAPAAHLTCVDATREDVDQVALEFAQSGVKHFVALRGDPSEGVGAKY
RPHPGGYENSAALVRGLRELGDFEISVAAYPEKHPESPDFALDVDLLKRKVDAGATRALT
QFFYDNDAYERYVERVRKAGIFIPIVPGIMPIHNFAQVARFADMCGASVPELLARRFEGL
ENDPETRAMVATAVAAEQVYDLVERGVDEFHFYTMNRAKLVYAICHLLGLRGNGNGSNGN
GIHVAA
>A0A519MYG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTETIQNAQGKTLFSFEILPPLKGQNIQSIFDGIDPLMEFNPPFIDVTYHREEYEFKE
LENGLLQKKVVKKRPGTVGICAAIQNRYQVDAVPHVLCGGFTKEDTENLLIDLDFLGIQN
VVALRGDAIKSEIYFRPENEGHNYATELVSQISNLNNGIYLDSELKNVNTTNFCIGVAGY
PEKHMEAPSLDSDIYYLKQKIKNGADYIVTQMFFDNKKFFHFVEKCRANGITVPIIPGLK
PISTKKQLNQIPHRFSVDLPDDLIMAVVKAKDNDAIKQIGIEWCIEQSKELVKAGIPVLH
YYSMGKAENIKSIAKEIF
>D1B7X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermanaerovibrio acidaminovorans (strain ATCC 49978 / DSM 6589 / Su883)|TrEMBL
MFIRELFGRGRPVISFEIFPPRGGVPVEEVYRTLGAIKDLAPDFVSVTYGAGGSTRDATL
EIASTVKNRFGLEVMAHCTGLCHTPPEVHEMVEDLMYEGVHNLLAMRGDPPRDRHVPEGP
SFPHGSDLIGYLRRAFGDEVCIAAAAYPEGHVEARDMEEDLAFLKLKVDMGAELLITQLF
FDNEIFYRFLESIGRLGIRVPVCAGIFPVLNARQVERIVSLCGVSFPPKFTRMVARYADD
PASLAEAGVAYATEQIVDLLAFGVDGIHIYTMNRPDTTRRIMNNIGLVSRRAVAGSGD
>A0A1Z9WKS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillales bacterium TMED59|TrEMBL
MSALRVSFEFFPPKTPEAEASLWKTVERLAPLNPEFVSITYGADGSTRERTHQVIESLLT
NTNLQPVPHLTCVGAPQEEIDSIAHEYWNMGVRQIVALRGDPERGAEADYVPHPHGYAYA
SDLVQGLLEKHPFELFIAAYPETHPQAISADADLENLKRKVDAGGHRAITQFFFDNEIFL
RFRDRVAAAQIDVALIPGILPVTNFNTLVRFAGACGASIPQSLSTVFEGLDEDPTTRQLI
AAHAAVSQAEDLGREGVEDFHFYTLNRADLSFAVCHALGVRS
>A0A1G0JL59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPLOWO2_02_FULL_56_15|TrEMBL
MSYAQIHPNWDRDPEYITEGFSIEITAKDIDGLREAAPKLPPDTPVAVTFLPGETLEARL
AAAKEVRKLGFEPMPHFSARRIKSEAEFKLMIEKMVAEAKVKRCFVIAGDSPTSEGPYLD
SSMLIDTGLFEKNGILAIGIAGHPEGHPNMTKEECFTALKKKCAMIHARGMKPIIVTQFG
FDPDAFMQWLVELRGKGIDAPVRIGVPGPTSIKSLLKFAARCGVSASSSVLAKYGISITK
LLGTAGPDRIVDIFAKSFGSEHGRVRLHFYPFGGLLKTVEWIEDYSKNL
>G5SJK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Wandsworth str. A4-580|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5D0HEU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Seonamhaeicola marinus|TrEMBL
MKVTDHIKKANGKTLFSFEIVTPVKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVQ
KDGLLDRKTIRKRPGTLGISVSLKHKYNIDPVPHIICGGFTKEETEYMLVDCHYLEIDNV
VALRGDAMKHQKYFEPTKGGHTYASELVTQITDLNNGKFLHEENLTEFKTDFCIGVAGYP
EKHMEAPSLQTDLKRLKAKVDAGADYVVTQMFFDNSKYFEFVKLARENGIDIPIIPGIKP
LAVKRHLQLLPHVFSIDLPEELVEAVDNCKDNKAVRQVGIEWAINQSKELKEAGVPVLHY
YSMGKSDNVKAIASALF
>A0A4R0HM05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella soli|TrEMBL
MFELICEVEPPTRPDLKKVRHQIGVMSPIADGFLIPDNHIGRATVSSVAVANEVQLMGAR
GIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVHGDDPAEGARTSQLTVRRMIEQTRETT
YPGCDPFKVGAATRLRPVPKWKAEADFLYVQVSYDLDELLRWRESVELDIPVYAGVMVLA
SAQMAHNLAKLPQLQIPADLIEAVERDRDAGVDHACEQILKIRDSGAFEGVHLIPVSRYR
QVAARLERDL
>A0A8H4BRA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor circinelloides f. lusitanicus|TrEMBL
MKVIDKIHKAEQEGRPFWSFEYFPPKTPQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
DLTTEIVATAQSVYGLETMMHLTCTNMPVKQIDDALEAAKNCGCQNILALRGDPPKGQAN
WESCKEGFEHADDLVRYIREKYDDYFCIAVAGHPEGHIDNPDKEDDLLQLKKKVDAGADL
VVTQLFFDIDSFLTFYKKARAIGITVPILPGVFPIQNYTGLKRVISFNNNFVPQKIWDDL
EPIKDDDTAVKEYGINLTVEFIKKFREIGVNGFHIYTFNLERSSRIVLERLNLMAPVESI
KPLPWNPSLTSKRAKENVRPIFWKNRAKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
INLKYPVDQCLEMWGSPTSIDDVAQTFARYCKGQIAGIPWSAQQLDAETDIIRQRLAAIN
LLGYLSINSQPAVNGVKSSHSVYGWGPKNGYVFQKAYLEFFVSPEKLDELIEKIGKDPQV
TYYAVNKQGDLRTNTQSDEPNAVTWGVFPGKEIVQPTIVEAVAFMAWKDEAFELWNRWAR
IYERESESAELILDITKNWYLINIVHNDFQDENGIWRLFDLEIDGEISRKLLQSNTVAR
>A0A6I8SM24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenopus tropicalis|TrEMBL
MESYGRLPKSCREGSKSESGLRMVNANSSDSGTASCSSAEDSKESSRCSTPVLDVERHER
LKDKMRRRVEAGDRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSD
KETSSMVIASAAVNFCGLETILHMTCCNQTKEDITKHLHKAKHLGLKNIMALRGDPTGEE
WEEEAEGFNYAVDLVTHIRHEFDDYFDICVAGYPRGHPEAEGYDQDLKHLKEKVDAGADF
IITQLFFRAETFLTFINDCRAIGITCPILPGIFPIQGYGSLRQLVKLSKLEVPQEIMDVI
EPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDVLKRLGMWKEDPR
RPLPWAVSAHPKRRVEDVRPIFWASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGELKDYY
LFYLKSKSPREELLKMWGQELSSEESVFEVFTYYISGEPNPNGHKVTCLPWNDDPLAPET
NLLKSELQKVNKRGILTINSQPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVTA
LIKVLKRYEPRVNYHIVNVHGQNITNAADLQPSAVTWGIFPGREIIQPTVVDPVSFMYWK
DEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLNTGP
>A0A7Y1SXR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MAKMNVTNLNATELAAVRNVIENLHYELIPLSNVIEQAAFLPERATVSVTASPAKGMQAT
IDLSLQLQDMGMHVIPHFSARLTTDRAELEANLKAIDKAGIHRVFIVGGDADPPGEFFDA
FSLLQAIDDIGHTIDSFGITGYPEGHPIISDELLEQAIVDKVPFAQYITTQMCFEPDTIT
DWIGHQRDRGVELPVYLGIPGSAELKKLLGISARIGVGD
>A0A7C3K1J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTKSNIEKILESGGFVVTSECGPPRGADVEVIRKKGALLRGVVDAVNVTDNQTSVVRMS
SFSSCLILKEMGFDPILQMVCRDRNRIAIQSDILGAAALGINNMLCLSGDHQRFGDHPKA
KNVFDMDSIQLIQTVKTMRDEGRFLGGEEIKGRPVLFIGAAENPFADPFEIRAARLGKKV
RAGVEFIQTQCIYNVERFERWMGEVRERGLHERCAILAGVTPFKSVGMARYMKNSVPGMD
VPEEMIERLKGVPKERQSEEGIKICVETIQRLREIPGVRGIHVMAIEWEEKVSEIVKAAG
LLPRPQV
>A0A7Y9LRV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychromicrobium silvestre|TrEMBL
MSPPSILSEPRERVSGQHSAPVALSYELFPPRSPAAVDGLWATIRELESTNPDYVSVTYG
ANGSNRDTAVELLHRLLSQTTLRPLAHLTCIGNTADELAGIIADLLDAGVRGILALRGDH
PSDGSEEHPPGALNFAQDLVELIRRVEQRRSAMLAAGKVAIGVAAYPTRHPESPSEQHDI
EVLLAKQRSGADFAITQVFFHPEQYADLLLRARRAGVSIPIIPGVMPFTSLKRLQRLAQL
TGVQPAPELLAQLEAARDDGERRRVGVRATVQLAKAALDAGAPGIHLYTFNQHQAALDVL
DRLDLFRPVPPAARLSQRPTDHLVEDPK
>R7ARZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides pectinophilus CAG:437|TrEMBL
MESLREYLKGHRLITDGAMGTYYSEITNNPEAFAEFANIERPDIIERIHNEYIDAGAKLI
RTNTFAANTQMLGIGRDELKKLIEDACRIAQRCADGRAYVAGDIGPIKENAESEGSAVEE
YKMICDIFLDMKVDAIRFETFADFDDIKEVAEYVRSKSDMFIMADFCLNKNGFTAGGISA
ARIMQQAGQMDCIDSCGFNCGIGSGHMNNIMQKLTFAKDKYMSCLPNAGYPEQMNNRMVF
MNNASYFCDNMQKISAYGMNIIGGCCGTKPAYIRELCRRIGDAVPAGRTETSDGNEPVNG
NNPAEAADIRVNEKRPNEFMQLFKSGHKVVAVELDPPYDAKYDRLIEQAQYLKSRGVDIL
TFADSPMGRSRVDSVLMSLKVTQETGMMVMPHVCCRDKNVIAMRSTLLGAYINGIRQLLL
VTGDPVPSVSRVSTTGVFDYNSIRLMNFVKEMNQEHFADEPLYYGGALNVTLGRIDRIME
RMQKKIDNGASYFMTQPVFSKEGIERLAIIKEKMDTKILCGIMPLVSYRNANFIKNEFIG
IDVPDEIVARYSPDMSKEEGEAVGAQIANELIGQMYDYVDGFYFMLPFNRVSLMDKININ
NR
>A0A534S182|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MPEGFIERLRGGPVLCDGAMGTQLYERGGVTFDRCLDELNLSNPELVKSVHLDYIRAGAE
IIETNTFGANRPRLATHGLEERVTELNEAAVQLAREARRLTGQRIWIAGSVSSLGRFLSP
LGPVTPVQARQVFLEQIEALAKAGADLLILETFTDLREMREAILAAKEVCNLPIIAQMTF
TEEGKTLAGDMPADIVPALEALEIQVIGANCSVGSEYMLQVVEQMTKIAKTPVSAQPNAG
FPTYQGGRFLYRSAPEYMAQHARRMVEAGVTVLGGCCGATPEHIAAIRDALQGIRLTHAG
RSSVAVVKRPRSTTPPAPAVEPTGLSCKLGRKFVVTVEVDPPKGFDVSSALEALSELKAS
GLVDAINVADNPRAQGRMSALAMCTLIQSRLGMETILHLALRHRNLVALHSELLGAHALG
VRNIFAVMGDLPRTGDYPDATSISDITTSGMIKLIKAFNSGVDLTGKPIEQATSFLVGCA
FNLGAADMDKELRTLDRKLKAGADFILTQPVYTAEAVEKACQHQGGFPAPLLIGILPLRS
HRHAEFLHNEVPGMVIPAEIRERMRLAGDHAAEVGIELCQKLLRDVHGRVGGAYFLPPFG
RYDTVLRVLEGVRGVLPDLGKKVR
>A0A7C1YT77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKAGSRLEKILEAGHFAVTGELGPPRGADAEVIKEKAEHLRGKVDSINVTDNQTSVVRMC
SMTVCKILLGMGLEPNLQMVCRDRNRIAIQSDLLSAYALGI
>A0A8J6N992|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfatifera sulfidica|TrEMBL
MLVKDLLKKHKTTFSFEFFPPKEDAAADRLLETISNLMPLGPSYVSVTYGAGGSTRDRTH
DLVVRIKEKTNITVVSHLTCVGSSRAEIHTILEKYNKAGINNILALRGDQPQGTTSTVEQ
KDGFDYASDLVAYIKKHFPGMCVGVAGFPEGHPGTPNRLQEIDYLKAKVDAGADYIVSQL
FFDNRDFYDYCERCELAGIHVPNIAGIMPVTSKSGLIRTAELAGGARIPARLLRAVYRAE
DDDYVKKVGIHWATEQIRDLLDNDVRGIQFFTLNSSTATQEIYSNLGVRDSSRLRTA
>A0A8J6NCM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfatifera sulfidica|TrEMBL
MKSGSNLEKILKSGTFAVTGELGPPKSGNPEVVREKARLLKGNVDAVNITDCQTAIVRMS
SIAAGLITQSEGVEPVIQMTCRDRNRIGMQSDILGASALGLKNLLCLTGDHQKFGNHAGA
KGVFDMDSIQMLGMMREMRDEKRFQCGEAIKEAEPELFLGAAANPFAYPFEYRAVRLGKK
VAAGADFIQTQIIYNVEKFAKFMEMVRDLGLDDKVYILAGVTPPKSLGMARYMQKFVPGM
DVTDDVIKRMQGAKDKQEEGINICVDIINQVKEIKGVAGVHVMAIEWESAVPEILSRAKL
LPRPSIMAEEDAPAAVEATSEPREEIQVRSVDTDSVLAQAREEAAAIVATAQAEADRLMA
QATSRQQTTAQTTGTIEVPAGAIDEAGEHAMNEKERVMALDAMNMGLAALKKAYGLSDEQ
FEAIVGFAGAQSILNRDPQITTPAAPAVPSTPAATPAAPTPAAPAVDTAKADAEAKAKAE
AEAKAKAKAKAKAKAEAAKAEAEAKAEAEAKAAAEAKAAEAAKSAPVAAADLGVPALDLE
KIALSDRASKIDSKLYAEKYTGTIRETVLGNDDNTITVGGAASMPFHLFEGEQPNKAMIA
MEITDTAPEEWPQTLMQHFDDVVGDPIAWARKCINEFGAQSIAISLASTDPNGMNRSAAD
AAKTASSIIEAVDVPIIVWGCGNADKDTETLRELTSVVGTKKVCLAPLEDANYRSIGATA
MAFQHPVVAASPIDVNLAKQLNILLQNLGVSLESVLMDPSVGALGYGIEYTYSVMERIRM
AALTQQDDKLQVPIICNLGREVWKAKETKLASDDMIGDQETRGVMMEALTATCMLLAGGE
ILIMRHPKAVAMTKSLIDGLMD
>A0A7W0KX63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MKLLSRRRRPAVTADRPSPSSDGDRARRAVLAAMRHELVPLKNVDAAIDALPPGSQVSVT
CSPAKGLEVTEELTARLLDLGHDAVPHLSARMVTGRDHVARLAAWVRDHGVREVFVVGGD
GTVPAGPYADGAAFLRDLLDHDTGLRQVGVPAYPDGHPMIDVGALRAALRSKQELIAEAG
VQATMTTQMCFDARRVTSWLRDTRAEGITMPVVLGVPGVVDRARLMTMGVRLGIGASLRY
LRKNRSTVTALLAPGGYDPTELVTSLVDQVEPLGLAGLHVFTFNAVADTVAWQRSLLAAA
ER
>A0A6H0KFJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yokenella regensburgei|TrEMBL
MSFFHANQREALNQSLAEVEGRINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRAELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A7V0TTL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MENNSFKNALLDPRIFSVTWELVPGRGAKETAQENVLASASQAADGKKVHALSLTDNPGG
SPAMSADFIGCEILKLGIEPLVHFSCKDKNRNSIESQLYALDRAGVRNLLVMTGDYPVSG
YMGRPSPVFDLDPIHLLQLISEMNKGLEYQGPKGISRLKPSDFFAGAVVSPFKATEAEQM
AQYYKLKKKIDAGAQFIVTQLGYDARKIHEAFLFLKQRGFNLPIVGNIYILPYGAARMMN
NNDLPGSVVTDKLLAEIDQERNNPDKGVKARILRAARMYAIMKGIGFNGVHIGGHNIKYE
QVEEIIRQGDTLAGQWTELIKYFDYPMENGFYYFERDPKTGLNKEAQIIRQSAKASAKLE
ISYSISRFFHMLMFKPGKKLYGIMKAISRKIAGSKLENIFHKLEHVTKVVIFDCKDCGDC
ALIDVAYLCPMSQCPKNQRNGPCGGSYQGWCEVYPLKKQCIYVRAYARLKNYGEEAQLQQ
NIVPPCNWDLHQSSSWLNFYLEKDHNANKQDNSPSGK
>A0A4R2T4H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cricetibacter osteomyelitidis|TrEMBL
MSYAKEIDHLNYSLANLNGEINVSFEFFPAKNEKMETMLWDSIHRLAPLKPKFVSVTYGA
NSGERDRTHGIVKRIQQDTGLVAAPHLTGIDATPDQLRVIAKDYWDSGIRNIVALRGDEP
PGYAKQPFYAADLVKLLKEIADFDISVAAYPEVHPEAKSAQADLLRLKEKIEAGANRAIT
QFFFDVDSYLRFRDRCAAVGIDVEIVPGILPVTNFKQLQKMATITNVKIPSWMPKMYEGL
DNDQTTRNLVAASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHMLGVKPGLQKTIQL
NYRA
>A0A853LFF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. E2462|TrEMBL
MMSADSDCPKRMEFGPCGGVRPDGQCEMRPGACAFEDIVPWSGPQPPPRPARAPLVLTDF
SCTPFDRADVAATAGLLAPGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVAPWITLSCRDR
NRVVLEQELRGLRSIGVETVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGVVPAV
PETPTAPPVRGRPARLVEKQRAGAGLAVLNHVPFPDMVADFMAAALAGGLTIPVIAAVAV
FTDSVSAAVLEGLPGLELDAAVTQRVLGAADPVSAGIAAAVDEARALLSIEGIEGVNVSG
LASASGARVGAEIKAEVGRRIRVEAL
>A0A6N8ZZ44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MDHGPQSHPTSRLAGLKGVGVVDLSPEARRRIRRILEEPKFELLPLGNVLEQCRYLPSGA
QVSITASPTRTLEHTLDVAADLAMWGFEVVPHLSARMTKDLTHLAALLKRIEDLNISRVF
VVGGDAPQQGDFPDGFSLISGLEKIGHDLEEIGIPCYPDGHSVIPDDRLWQALYDKQPHA
RYMTTQMCFDGELIADFLVHSRAKGVDLPVRFGIPGVADRLKLARISTRIGVGQSVRFLT
KHRGLVSRFVRPGGFAPDELLEDLIPRLDGPESDVKGVHIYTFNQCDTTERWRQEYLAVL
>A0A7V9GGW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
RDRTREVVTRINDDHPFPAMAHLTCVGHTRAEVVALLETYAAAGVHNVLALGGDPPADGS
DPGGEFTHACELLELVQAVGGFSVGVAAHPELHPRSPDRASDRRFLAEKLAAADFAVTQF
FFDAAHYVELLDELAALGVDKPVVPGVLPVTNVAGLRRMAAMNGTDVPAGLMARLDAVAD
DPAAVAAIGVEVAVELCTDLLAAGAPGLHLYTMNRSSSVRAVLGALGGGR
>A0A6N7FKG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MARDTFELVCEIEPPVRPDLTRVRHQIGVLSPVASSFLIPDNHIGRATVSSIAVAHEVGA
MGGRAIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVYGDKPTSGARTSELTVRAMIEEV
RGYAEEPALRASPPFRVGVTTGLGGVPEWKRVADFTFVQVSYSVERLLRWRERAELEGLT
GPVYAGVMVLASVSMAQRLAAAIPDIDIPAELVERVGRDRSAGVAAACEQVLALRDTGAF
DGVHLVPVSRYREVAAHLEREL
>A0A7Y1X7Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MSTKRILHRWKSGRPCRSCPTKSSTQSHIYSSSRKESRVSRLKPARRWQPAWRPFKREAL
GDRALARVERIVKGPIYGCRMCGNCLLQETAFICPMECPKGLRNGPCGGSTPETCYVDET
RPCVWHEIHERAFATGREEKLLEVLPPLDWDKVGGETWGDVYRQTREVGFGAFFSGIRKQ
ETRSDVWESVFGPVRQPDWWQGDAEYHPPAYEEPASELERQLRDGAFVVTSEVAPPMGTA
TGKLVRETEMIRPYVTSVNFTDSPSATARMSSQACSIMALRGGAEPVMQIAARDRTRVGV
QAEVMGASALGIRNLLCLSGDSPAIGPAPRSRMEVVDIESVQMLWMLRRMRDEGVYLDGR
KIKSPPSYFLGAAASPYASRPEFQALREHKKVNAGAQFFQTNIAFEPKGLEIWLKSLADR
NILDKVYVLIGLTPLKSFKMASYMNDSVPGVSIPTTILDRLEKAGDPEKEKEEGVQITLE
LIDQIKDMEGVNGFHLMPVMWESIIPRIVTEAGLLPSGFTPPSNHDELIVGV
>A0A7C8DZM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEYKAGSNLEKVLKAGHFAFTGECGPPTGANVEHLKEKAGHLKGCVDAVNVTDNQTAVV
RMSSWAASIILLQEGLEPNFQMVCRDRNRLAMQSDILGVYSHGIRNMLCLSGDHQKFGNH
PEAKNVFDIDSMQLIYTAKTMRDEGKFLNGQDVDVPPRLFIGAASNPFAEPFEFRVHRLA
KKIAAGADF
>A0A554GJ07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus sp. Z5C101001|TrEMBL
MKIRNCLNPSRPSFSFEFFPPKTDAGVAALLRTVEELAPLDPGFVSVTYGAGGSTRDRTV
ELVTHIKQHTGIEAMAHLTCVGHTRDELRDVLRRLGAAGIENILLLRGDPPQGQTTFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLRHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRVGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVGALRGRS
>A0A432HKG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNLQRKFETGEFAILAEIEPPKGADVSEMVANAKRVKGDVDAFVVPEMSNAVMRMSSLGG
AMILQQEGLETVFQVCCRDRNRLALQADLLAAGATGIPNVMAVVGEDPSFGDHHQARAVN
DIDLIELLGVIHNLEQGRDMAGIELTGAPQFLVGTTANAGAPGISVELEAEEMMRRADAG
AGFFITPPLFDASLLKSFLTRIDSKKITVIPTVLLLKSLGMARYISRNMDHVHVPDTLIK
RIQSVPDKAREGIKIAAELVSELKTEGYQGVLLSTVGWEHRLPEIIEGI
>A0A496YXC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTESVLEKVLAAGHLAVTSECGPPRGAVPEKIREKADILRGYVDAINVTDNQTAVVRMS
SFAACLIIKQMGLEPILQMVTRDRNRLAMQSDIIGAYSHGINTMLCLSGDHPCFGDHPMA
ANVYDLDSIQFIQMVRKMRDEGKFQGGDDILNPPKMFIGAAANPFADPFELRVPRLAKKV
KAGADFIQTQCVYNVEKFEKWMEGVRERGLHEKISILAGVTPMKSVGMARYMKNKVPGMD
VPDELVKRISGVPKDKQAEEGIKICVETIEHLREVDGVRGFHIMAIEWEQKVPEIVERAG
LYPRPKI
>A0A101P2L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces yokosukanensis|TrEMBL
MALGTPSTRTDRARTVREILATGKSTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVSHPKGLTYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCDTPVIPEVLPVTSVKMLERLPKLSNAVF
PDALKERIVTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A661LBV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSESKTPSKLEKILSSGHLAVTSECGPPRGSDPETIRKKAEMIKDHVDAINITDNQTSVT
RLCSLASCIHLKLMGLEPVLQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQKFGDN
PQAQNVFDIDSMQLIQMVRLMRDEGKFLGGDDIVRPPKMFVGAAANPFADPFEIRVPRLA
KKVAAGAEFIQTQCIYNVERFKEWMRGVVDRGLHEKVYILAGVTPFKSAGMAKYMKNRVP
GMDVPDELVKRMSGVPKEKQPEEGLKICVETIQQLKEVEGVSGFHIMAIEWEEKVPEIVD
ASGLYPRPKVDD
>A0A661RVT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MELRNRFNVGEFVVLVELVPPKGVDISGMLKVAGKIRDKVTAFVVPDMAAAVMRMSALGA
AMILQQKGFKTVMQVCCRDRNRLALQGDLLAAYAGGITSLMAVAGEDLRYGDHHEAAAVD
DLDLIGLIEAVGTMRGGKDLSGAELAGEPRFFCGTTVNVGLGDADLAAEVAEMNRRATAG
AEFFVTTPVFDPAAIEPFRQLMDIRKQNVVPTVMLLKSIGMARYIQRNMAHIQVSDEIIS
RLQKAPDKTKESLRIARETIAALREANFKGVLISPMGWEENLPELFEQVE
>A0A661L6N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MVSNFKKALESGKFVVTCEIAPPKGTNLDKMRHHIELLKDKVDATNITDHQSSVMRYPSL
GGALLVKECGGEPILQMTCRDRNRLALQADLLFAYSRGVNNVLCLTGDSVIFGDHKEAKG
VFDLDSSQLIMAIRRMEKGKDLGGNELDGKVQFCVGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVYDLDNFRKFMDYARQFPVKILAGIILLTSAPMARFMNKNVAGVNVPQTLID
EMASAPKGKAINKGIEIAGRMVRQIREEKMCDGVHIMAIGREELVPEIMAAAGLL
>A0A396KZP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea sp. AF36-15AT|TrEMBL
MKIRELLRQEQTSLSFEVFPPKKDTDFANVETATLGIAKLQPSYMSVTYGAGGSTKGNTI
QLASEIQQKYNVPAISHLTCVCASKENIKAALNEMKSAGIENILALRGDLPNNFEGEVFT
DFAHASELVAFIKENGDFCVGGACYPEVHPDSPTKADDLEGLKRKVEAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIIPGIMPITRRAQVKNAVKLSGCNVPERFKNIVDRFGDNEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEIAAGIQANLSEILKA
>A0A285LPT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia amikacinitolerans|TrEMBL
MRGRSTPGRPSPTPPIVSGTPSVVQSLQVHSGRMVPFSVEFNPPRDAAGEARLWRAVREF
ERMHPAFVSMTYGAGGSTKDRTVRVTGELAQETTLLPVAHLTAVGHSVAELRSLVGAYAD
SGIRNILVLRGDPPGDPLGEWHKHPDGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPD
LETDTAFLAAKLRAGAEYSITQMFFEVDHYLRLRDRVVAMDPVEGAKPIIPELMPITSLR
TVTRAEELCGRELPASVLERLRKAAGDGPEEDRAAVREVGIEIATEMAQRLIDEGAPCLH
FITLNFAKATSEVLTNLGYGVTAAPMSA
>A0A2A2QHL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiae bacterium Tous-C5FEB|TrEMBL
MHISDILSKTKPSLSFEFFPPRSEPAWGDLYETIRNLEELRPSFVSVTYGAGGTTRELTH
DLVLRIRQTTSIPPVPHLTCVGHTKEEIHSILERYAAAGVSNVLALRGDPPKDQPDYDWS
NGDFRHAADLVAFIRVFNRSGAHPDPRGFGIGVAGFPEGHPTTPNRMLELEHLKAKVDAG
ADYICTQLFFDNHDFLDFRDRCQLAGIEIPIIAGIMPVTSLQGMKRMAELAAGARYPAKL
IRTLNRASSNPESVERAGIHYAAEQCASLLNEGVDGIHFYTLNKSHATREIFKSLGLAPT
A
>A0A2S5IVN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter pityocampae|TrEMBL
MPELPVRIEVVPGAGLEDRLRAHLPAPAVVTVTCLPHHGPGAAVDTAVRLAEAGYTAVPH
LAARSVAGRSELAGYVTRCRDAGIRDVFVVGGDAAEAAGPYAWSGPLMEDLAELSGGALR
LGIAVYPEGHPASTDQELRRTLLAKQVLASWCVTQLCFSPDILRAFVPMLRDGGVTLPVW
AGIPGPVRISRLLRLAGTIGVGGSVGFLRRSAGGAETGSVVRQLLSSASYDPAPLMTALD
GAGYEGIHLYSFNDLAGLERSGLARLPRA
>A0A0A1GX36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paucilactobacillus hokkaidonensis JCM 18461|TrEMBL
MKLTDIFKHKTVFSFEVFPPHGEAPVDKIRNTLTNLDHIHPDFISVTLGAGGIGAQNQTV
EIADFIQNNLNIPAVAHIPGLYQSREDVRKLLAELSDHHITNILALRGDKITGKNPVGDF
THANELVSFIKEQADSFQIIGACYPQCHQEAANLTTDIINLKRKVDAGADHLISQVFYEN
QCFYDFVEQTRSAGISVPIEAGIMPVTNKNQIERMAKISGKPLPEKFVTILNHYADNKEA
LRDAGIAYAIDQIVDLVSHGVDGVHLYTMNHSRVAQRIWDATASLFQYSEVEPGFHL
>A0A1Q6FYR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:1060_57_27|TrEMBL
MKVSEVLSTSTKAYPSLEIVPPQTGITRTELLDSIRPFMEFSPRYINVTCHRDEVEFIPR
PDGSYSRRLVRRRVSESVVCAAIQAEFKVDVVPHLICGGSNAEQIEFQLQDFRFMGMDNI
LALRGDCISGEKRFTPEAGGYSHADELVRAVHRFEREHLNAENYFCIGVGAYPEKHFEAP
NLEYDIEMLRQKVDSGADYIVTQMFFDNTVFYRFVDRCRAAGITVPIIPGLKPLSTYRQV
QLLPETFSIDIPQELTKEMEAFRDDRDACYRIGQIWCARQCRDLIAHGAKAVHFYTMGRA
ENIVGILRECF
>A0A3D5WG15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MHFQELLDSKKFLVISELQPPKGTDLTEFYDYAEKMRGRIDAVNVPDLQSAVMRLGSLSA
SYLLKEKGFTTICNMTCRDRNRLALQSDLLNISVLGIENIVLSRGEEPSLGDHPDTKPVF
DLTPLELISAIRDLQKGYDMAKSDLHGTPKFCVGSTVNSSAQRGALDLEIKKMEEEIRAG
VDFFLTTSVFELNIFENFIRKIEYLKVPIIPGIMILKSVGMARFMNKHVEDVFVPEVLIE
RLMKSADKPKTSVEIASELINGLKPLCQGVHLIPFGWEDKVPSIIEKAGLY
>A0A661QNL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKAKTPSKLEKILAAGHLGVTSECGPPRGSDMEVIKEKANLIKDYVDAINITDNQTSVTR
MSSLAACIQLRLMGLEPVLQMVTRDRNRIALQSDILGAAAFDIHNILCLSGDHQSFGDCP
TGQNVHDIDSMQLIQTVRLMRDQGKFLGGDDIKRPPKMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNMEKFELWLKMAGDRGLLDKVYILAGVTPFKSAGMAKYMKNRVPG
IEVPDKLVKRMSDTPKEKQPEEGIKICIEQIQRLKEVQGVHGFHIMAIEWEEMVPGIVKK
SGLYPRPSVE
>A0A1U9NB90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrio sp. PSBB023|TrEMBL
MNDSQPRLSFEFFPPKTPEGKEKLIKVRDQLNEFAPDFFSVTYGAGGSTRDNTKGIVTQF
KADGISIAPHLSFGGDDEVTIKSLIQEYKDAGVDRIVALRGDMPSGVGGAYQLVYANELV
AFIRNHFGEHFHLEVAAYPEIHPQAKSYSDDVRYLKGKFDAGANSAITQYFFNPDSYFYF
IDQCQKAGITQPIYPGIMPIINYKNLTRFSDVCGADIPRWLRKALENYGDDEASLKAFGV
ELVTDLCDTLLENGAPGLHFYTMNQTEPTAEIVRNLGLIPTDD
>A0A0B2A3L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium mangrovi|TrEMBL
MPATVEVPVSFELYPARTDAGIPALHETVRRLAAIDPAFISVTYGAGGSTRDRSLALLRH
ILDTTDVEPMAHLTCVGTSYSEATALIREFLDAGITRFLALRGDPPEGAAEGDDFLGDIR
SAAELAQLIDRVQAERVPYGEAPVPGLPQAARVVEPHDVQIAVAAFPNGHPRSRHSREHI
DALLAKEAAGATLAITQLFFYADDYLSFVDRSRTAGVTIPILPGIMPIISPRRLQRVLQL
SGESLPGELAVALDVEPTAEGQRAVGIAHASALVRAVVEGGAPGVHLYAFNNHATVLDVL
AAADLLPSRA
>J6I9Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. CM59|TrEMBL
MKVTDHIAKAKGKTLFSFEIVPPKKGNNIEELYKNIEPLLEFKPPFIDVTTSREEYLYKE
HPNGLLEKKLIRMRPGTVGICSAIQHKYNIDTVPHVLCGGFTKEETEDLLVDCFYLGIDN
IMALRGDAMKEERYFRPTKNGNVYALDLVKQIDNLRKGVYLHDTLETNIGMDFCIGVAGY
PEKHIEAPSKTFDLEKLKEKVDNGADYVVTQMFFDNKKYFEFVAKAREMGIHVPIIPGIK
PVSVKKHLNILPQAFFLDFPEELVKEIEKCKNNEAVKQVGIEWAIAQSIELKKAGVPSLH
YYSMGKSENIIQIISQVF
>A0A534UU67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRITDMLRFAAERGEPVFSFEFFPPRNDAGVAALFETLRALRPLAPSFVSVTWGAGGSSR
GRTLEMVTRIKRETEIEAMAHLTCVGASRKELEEQLAVICDAGITNVLALRGDPPRGQRE
FIVHPEGLAHATDLVQLAREVADKRGVSLCIGGACYPEGHPETRDLAKDLRHCKQKADAG
ADFLITQLFFDNRRYFEFLGRARAAGIDVPIIPGIMPITNVDQIERFTALCGAHIPAGLS
AALRARRDDPDAALQLGVAYAALQCAYLLRGGAPGAHFYTLNRSTATRAILAALRAQEPW
RDA
>A0A496YB71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEYKAESNLEKVLKAGHFAFTGECGPPQGANVEALKEKAKHLKGCVDAVNVTDNQTAVV
RMSSWAASLVLLQEGLEPNFQMVCRDRNRLAMQSDILGIYAHGIRNMLCLSGDHQKFGNH
PGSKNVFDIDSMQLINMVKLMRDEGKFLNGQDIDVSPRLFIGAASNPFGDPSEFRVYRLA
KKIAAGADFVQTQCIYNMKRFREFMKQVVDMGLHEKCAILAGVTPMKSVGMARYMAKQVP
GMDVPEELIKRLQGAGKGKVAEEGIRFAIEQIEEFKEMEGIAGVHLMAIEWEHRVPEIAE
RAGVLPRPEI
>A0A428BVD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A7Z8RCL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. WL2|TrEMBL
MRRPTHRASRDGYHPIRVSIEFFPPKTDEMEKVLWSSIERLAPLQPKFVSVTYGAGGSTR
ERTHNTVARMIRETTLKPAAHLTCVDASREEIDAVVQSYWDVGVRHIVALRGDPADGVGH
AYRPHPEGYATTAELVAGIKRIGDFKVSVSAYPEKHPEAATLDADIDALKAKVDAGADQA
ITQFFFENEVYLRYLEKVRAAGITIPIIPGILTVQNFKQSANFARRTGASVPYWLAARFE
GLDNDVETRRLVAAAVAAEQVLDLVDEGVQDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AEKAAEKAAA
>A0A7L0MLA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amazona guildingii|TrEMBL
MVNETQHSCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCDQTRDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEDVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFVITQLFFRSETFLK
FVKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7W0WN07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MGTMLYGRGVFLNVCYDDLNLKQPDLVRDIHREYVRAGAELLETNTFGANPLKLAIHGLA
GDTERINAAAAGLAREAAGARAAVAGALGPLGVRVEPFGELSLDEACAVYERQVSGLLAG
GVDGFILETFSDVNELGAAVKAIRTRSDLPIIAQMTVGTDGKTHYGTDPVVFGPAVAAMG
VDVIGVNCSVGPHGVLEAVEKLARVVTLPIAAQPNAGLPREVGDRKIYMASPEYMASYAR
RMVEAGARFVGGCCGTTPDHVRAMVGFVQSVSPRHAFDTGTLPAPAPAVALDPVPLAGRS
RLGAKLAQGRFVTTVEIVPPKGVDPAPMFEQVRQLKAAGVDAVNVPDGPRAQSRMGALLS
ALMIEREVGLEAVVHYACRDRNLLGMLSDLLGAAAAGIRNLLIITGDPPKMGPYPEATAV
FDIDSIGLTNLVSRLNRGLDPGGNPIGQPTRFVIGVGVNPAAPDFERELKRFAYKVEAGA
EYAITQPVFDLEQLDRFLGQVEGFRIPIIAGIWPLVSLRNAEFLANEVPGVSVPDTILDR
MRTASAGGKEEALAEGVRISREMLAAVADRVQGVQVSAPLGRVPVALEVLEAAPIVPVGS
QGYTPPT
>A0A645I5S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MGVKRLVALRGDLPSGYGMGGEFHYASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEA
DLQAFAAKVRAGADSAITQYFFNADAYSRFVDDVRRLGLDVPVVPGIMPIMGSTQLMRFS
DACGAEIPRWIRLRLQGFGDDTASIRAFGMDVVAQLCEQLRRAGAPGLHFYTMNQSATTQ
ALCQRLGLIG
>A0A3R9QU40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salibacterium salarium|TrEMBL
MISEIKRRILIGDGGMGTYLYEKGYTCSFEAMNLLDPSVIEEIHQEYVEAGADVIQSNTY
AANRVKLEKYDLEHDITRINQQGVRLAKKAAADDTFVVGTIGGIKGVQQIDISTQHIQHA
FREQAEALLSESPDGLLLETFYDLSELLEAVKVVRELTTIPVIAQAALGEVGVMHGGTPV
KDAFAQLKEAGADIVGLNCRMGPYHTLRSFEPVPLMDDVFFSAYPNASLPDLDDGRFVYQ
SNPDYFFEKAQDLKKQGVRLIGGCCGTTPEHIAEVAKAVKNSSPVETKEIAYTTFTESPV
SSVPSFNSRLDKKNTEKPSVIVELDPPKKLSTDKFMEGVQALYNAGADAVTMADNSLATP
RIDNIAMGAMIKNRTEARPLLHIACRDKNLIGLQSHLLGLHALGIQDVLAVTGDPTKVGD
FPGATSVYDMNSLKLISLMKEMNEGRSFSGKSLGEKTSFTVAAAFNPNVRNLHKAVQRLE
KKIDAGADYFMTQPIYGENQFEEIYEATKHLSVPIYVGIMPLISRRNAEFLHNEVPGITL
TDDIRERMAQCGEDRDKARAEGISISKTLIDKALEYFHGLYFITPFLRYDITAELTTYVR
QKEFSGTVGTQGKEWDI
>A0A2Y9UEY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAARLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGTAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
AKLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A316ULJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jaminaea rosea|TrEMBL
MPSSSSSSSSHITTKIAQHTSSSQSRPFWSLEFFPPKTSQGQANLLARMSRMNATLSPQW
NHVTWGAGGSTKERSLELAARGQRGVWDPVVPMEGVREDLDCEAAMDSCLHLTCTNVDKD
SLDETLEEAKRLGIRNILALRGDPPRGDEYWVAADSRFQRATDLVEYIRQSHGDFFCIGV
AGYPEGYCDSLDQDIDRDVRFLKAKQDCGADFVVTQLFYDVDVFVEWYRRCREAGITIPI
LPGIMPIQNYQSFRRMTNLCKSKVPPTVLAALEPIRFDDAAVKEYGVHLAISMIARLYLE
TDIRGFHLCTLNLEKSVRRVLEGLGWVECQQEGAETLPATGAKVPSFKSRDTHANIDYRA
VTEEALARAQAAAKGANRSAAAATSDATWDEFPNGRFGDARSPAFGEIDGYGVSLKVPPA
DALRIWGYPVSDDDISAIFSSYLVDKIQCIPWCDAPIFDETLAIQQWLLALNAPGKGWWT
VGSQPAVDGVSSADPTYGFGPRDGYVYQKAFVEFFMSESDKDALAARIEAEGQGKLTFFA
GNRRGDFETNMPQGGQVEAVTWGIFPGKEIAQPTIIEEESFKAWRDEAFDIWREWESLFP
KRSATAQLMREIGEKRWLVTVVHHDYKDEAGLWRFLRADVAQPQAAPQSPSPTTVVSAPG
KVLVAGGYLVLSPAYPGLVISTDARFYSVIAAGTAGRLSIRSPQFTQAVWHFDLDIESGA
LSLSSESASSPYAGRSPFLCLALVYSLALAYQRVPLPALRAKLAQGLEITVVADNDFYSQ
KAEGSEDAPTSQYLSSLAPFHPLDVAIRDVHKTGLGSSAALTTSLVSSLLLHLGVVRTLE
NDDDLALALAHNTAQLAHCAAQGKIGSGFDVSAAVWGSQIYRRFDAKVLEPLLASIPKIP
VTGAPKGEAGELASLRDVESLGPHLDPLQQPLWKPSPLSATTTSNAHPTAFEGLAATTAS
STSLRPAPLSLPAGISLLLADVDAGSNTPSLVSSVQAWRTKKPEWAKQLYDVIASSNSAL
ADAFARMALAQGGAADEYKETLEWAKGRKSSEWGGVSDGCGHGHAHGVHDGGETGTSSST
RLAESETGRALIAARDALRSTRAGMRELGRLSGAPVEPDSMGRVLSAAIDGVPGVLGGGV
PGAGGYDALYVLYVEAEGRREALEEMLRAAGKREKGESERLRVGVLMSGAGTGGVRAESL
QAVRGLRERAEGVIM
>A0A699Y612|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSAPTSLRVQAFLDAFSLEVSARAMPALGAEATRIPRGTTISIPWLASEDDDARLAAARR
VRELGFEPMPHLSARRIGSRAVLERFLQRAANEAGVAQCLVIAGDLATPAGPFADSASII
ESGLLERAGIKVVAIGGHPDGHSVLGSDACWQVLEHKCQSIEARGMAPMIITQFAFDADI
VLAWLHALRARGIHVPVLVGVPGPASIARLVRYAAMCGVGASALMLSRYGISIGRLLGSA
GPEVFVDRLAGGLTDAHGLVSPHFFPFGGIAQSLDWINQHRALPSVARR
>A0A644T225|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MHIGKMIRELSAPFYSLEFFPPSDTAQLPDFYATVDRLRALNPLFASVTYGAGGARQQNT
LAVTAELARRGITAMAHLTCVGAEPQSIAAFLHDLQASGVNNVLALRGDPPADKPWDWNK
AHFRHASDLVAFAREQQPDLGIGVAAYPAPHPESPTFADDRRCTAEKMRAGADFALTQLF
FDAREYEDLVSHLRGQGITTPVIPGILPIQSFDSLRRVLSLCGANIPGKLYLALEKANND
GGAEAVRQVGLDYAVRQIRSLLDAGAPGIHLYTLNKADMCLRLAEAVGTL
>L7ZVY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. GHH01|TrEMBL
MGLLDELKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIAAMAKALSDRTPVTEKTVKRRAVSVS
VQADRPAPSPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACSGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A4Q7H9U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas moorei|TrEMBL
MLWIYLKYKVETLLSRGLNVEITTQLSFNADAVISWIKRVRHLGINVPIRIGIPSPSSLG
DMLNFARQCRVSTSIQLLQRYGWQVSYFLGTVGPEKFLGSLIKKLE
>A0A1G6T1A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus telluris|TrEMBL
MSAEGAAVASRPPAGSPHPAGGRRGRRPWTAALESALREASYEVLPLRGAEQAVVEHVPR
EVPLTVTTTEAKGLTRTLELAERLRGHGFDATPHLAARQVRDGAHLTDLVARLRAAGVDS
VFVIGGDAAEPAGPFPDALALLEALRAGGHSFARVGIGGHPEGHGHLPDELVERALEQKA
PHATHVITQMCFSAATTTAWARQVRQRGVHLPIRVGLPGAVTRQRLVRVSAGLGLGQSAR
FLAKQHSVFWRFFLPHGYRPDRLLTGLAPALGHPDVGLQGLHLFTFNEVARTEAWRQEWL
TRLRDQASV
>A0A246HXU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIEFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLVEGGAPGLHFYTLNLARPTTSVLKLLQG
>A0A1H1IA37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas moorei|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRALGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EHVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A229GBH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. DAB_AL32B|TrEMBL
MTKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPSYFSVTYGAGGSTRSRTLDIVQALCA
RGNTDIAPHMSCIGDDKSEIAELLDLYKGLGIKRLVALRGDLPSGQVGMGELPFAVDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFDSDIDNLVNKYQAGANTSITQFFYNADSYLYLR
DTLEKRGIDTIAQPLVAGIMPITNSSNLVRFADSCGADIPRYVRKQLADFGDDSKAIREF
GFEVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLSA
>A0A1S1GJX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. HMSC75E02|TrEMBL
MSQDRRFSFEFFPAKTEAGHEKLLATARQLAGYKPDFFSCTYGAGGSTRDRTLVTVLQLD
GEVNVPTAPHLSCVGDTKAELHALLAHYKDAGIRRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGDHFHIEVAAYPEVHPQARNSEHDLANFVRKVKAGADSAITQYFFNADSYFH
FVERAQKLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIASIQSFG
EQVITEMCERLLDGGAPGLHFYTLNQADPSLALWKNLKLPR
>A0A2J0SN04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSAPTSLRAQAFLDAFSLEVSAKAMPALAAEAARIPRGTTISIPWLASEDDDARLAAARR
VRELGFEPMPHLPARRIGSRAALERFLQRASSEAGVAQYLVIAGDLATPAGPFADSASII
QTGLLERGGIKVVAIGGHPEGHPVMGSDECWQVLDHKCRAIEARGMAPMIITQFAFDADV
VLAWLDALRARGIDVPVLVGVPGPASIARLARYAAMCGVGASASMLAKYGISIGRLLGTA
GPEVFVDHLVSGLTEAHGLASPHFFPFGGIAQSLDWIKRHRAQASVARR
>A0A1D1Y4X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anthurium amnicola|TrEMBL
MKVINKILKANEEGRPSWSFEYFPPKTQQGVQNLYDRMERMYRLGPEFIDVTWNAGGTSS
QLTSEIVATAQSVYGLETVMHLTCTNMPKEKIDKALKDAKECGCQNILALRGDPPRGQEH
WEACENGFSHAVDLVRYIREQYGDYFGIAVAGYCEGHVDNPDKNDDLNRLKEKVDAGADF
IITQVFYDVDLFLNWVKKCRAIGISCPIIPGILPIQNYNGFNKIITLSKTIVPQFVLEEL
EPIKYDDAAVKEYGIRLAVDMIKKMFSDGIKSYHFYTMNLERSTRLILETLEFVPLIENV
KPLPWCPSLSAKRKKENVRPIFWRNRTKSYIARTEAWDEFPNGRWGDSRSPAFGELDGYG
VSLKHNEKEALTLWRYPLKLSDIFDVFVQYCRGEVNSLPWSDLPLAEESNIIKEQLAHIN
SLGYLTINSQPAVNGVRSDHKIFGWGPKNGYVYQKAYLEVFIAPTQLDALISRIERDSNI
TYYAVNKQGDLKTNTQSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELWNEWAK
IYDAESISAKLITDIAENWYLINIVHNDFHNSDGIFKIFEHNVTYYEADR
>A0A3D1Q0N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosipho africanus|TrEMBL
MKISQIKDFFISIEVIPPLRGHSADNLYKAIDKIMPYNPAFISVTKHPPELEYYEIDGQI
LKLPKVKRPGTMGIVAALKMRYNVDVVPHLTCIGNSKFELEELLIDLDFLGIDNVFVIRG
DKKKNVIKKEWQYDYA
>A0A5N7Y9K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Starkeya sp|TrEMBL
MSSDVERRSRRAGGRPISVSFEFFPPKTAEMETTLWNSITRLAPLAPKFVSVTYGAGGST
RERTHATVERIVKETRLAPAAHLTCVSATRAEVDEVVRGYWDAGVRHIVALRGDPPGGVG
HTYEPHPEGYRTTAELVAGIRRIANFEVSVSAYPEKHPESPSLDTDLDILAAKVEAGATR
AITQCFFDNDLYFAYLDKVRARGIDVPIVPGILPVSNFKQAKNFSEKTGTFMPDWLAARF
EGLDNDPETRKLIAAAVAAEQVFDLVDRGVTEFHFYTLNRADLVYAVCHLLGIRPPQEVN
GAGDGKGQAAA
>J0R0N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bartonella tamiae Th239|TrEMBL
MAPKKLSRRADIGEKLKVSFEFFPPKSENMELSLWETVERLAPLEPEFVSVTYGAGGSTR
ERTGRTVERVINETRLKAAAHLTCVDATRDEVDDVVRQFRAMGIRHFVALRGDPSNGIGG
RYEPTPGGYANAIDLVKGLKAIDSDFEITVSAYPEKHPESPDFATDIDFLKRKIDQGATK
AITQCFFDNHFYEDYIEKVRKAGISIPILPGILPIHNFWQVKNFCTRNGTHIPEWLAQRF
DGLENDPKTHALVSAAVAAEQVLELVEQGVEDFHFYTLNRAELVYAMCHLIGIRADKRYN
ENHTD
>A0A7V8GHH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. SKDU12|TrEMBL
MGLLEDLQKQVLIGDGAMGTLLYSYGIDRCFEELNISKPEDIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEGDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETGLPIMLNVSMHEQGVLQDGTP
LSEALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQQSASEFRRQGARIIGGCCGTTPNHIRAMAEAVGDLAPITEKEVKTPAKEYIS
VQQERTEPGLNEIATKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGSLVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLTDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKRTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIREKMALAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELSTYIQ
QKDEQRKNIYLH
>A0A198A1A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus oryzisoli|TrEMBL
MKLDLRAALQREILTGDGAMGTYLYQMGFPVGISYEELNLLRPETVADVHRRYFEAGARL
IETNTFSANREKLSKYGLEGDVEAINRAGVELARNAVGDDAYVVGAIGSIRAGKRKNVRT
SEVEQSLQEQIGILLDSPVDGLLLETFYDLEELQLALRIIRSMSNLPVICQFANEGTGST
QDGVPLQEAFLRLRDEGADVIGFNCRVGPNGILRSMEKIAPIPGIPFSAFPNAGLPDYVD
GHYTYAATPKYFAESALRFADLGARIIGGCCGTTPEHIAAVAKALQGYVPAAPGKASAGA
AAIVLEPAPAKPAPPAGIPSLLDIVKQRKTVIVELDPPKDLDIEKFMQGSKALQDAHVDA
ITMADNSLAVTRMSNLALGYLVQERLGARPLIHIACRDRNMIGTQSHLMGLHALGIDHVL
AVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFVVGAAFNPNV
KHLDKAVQRLERKIEAGADYIMTQPVYDAKLIEDIYEATKHLSIPIFIGIAPLASGGNAE
YLHNEVPGIRLSDEVRARMDGLKGPEGRAMGVEIAKELLDTAMQYWNGIYLMTPFLAYEM
CVDLTNYVWEKSKRHDFHLYPLSK
>A0A847KAX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MLDSGHFAVTAEIGPPKHAGAHSIRHHAQLLKNHVDATNITDSQTAIVRLSSIASGVHIL
DCGIEPIVQMTVRDRNRIAIQADLLGAYSLGMRNLLCLSGDHQQFGNHPTSKNVFDIDSM
QLIYLMSRMRDEKKFFCGEEIKEYEPRFFIGAVANPFADPFEYRVDRLEKKIEAGAQFIQ
TQCIFDMERFERFMEMVRARGLDQRAHILAGVTPLKSWRAAKYIQTGVSGMIVPDSLVER
LKNAADPKKEGIKVCIEQIKHIRENIKGIHGVHVMAIAWEEVVPEIVEKAGLYPRPQVEF
NPEEND
>A0A3D8YYJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. BI001-red|TrEMBL
MKLLERLKTEVLTADGAMGTLLYAEGLDFCYEQLNIEKPDVIQEIHKQYIHAGADIIQTN
TYSANAYKLARYGLEHRVKEFNEAGIHIAKRAAAAGGQYVLGTIGGIRSIRKSDATIDEV
LSIVQQQAEPLLAGDPDGLLLETYYDFEELSAVVKHLRKQTDIPLIAQVSMHEPGVLQNG
LQLNDALHQLETLGADVVGVNCRLGPYHTIQAFEGVELPKKAFLSAYPNASLLDVEDGRI
VYVSETDYYGRAARLLRDEGVRLIGGCCGTTPAHIVAVKSQLANLAPLTEKTVVPHKPIV
IRDAEPTRYEPLHIKAKRERTILVELDTPRHLETENYFEGARQLQEAGAHAVTMADNSLA
SPRISNLAMASLVKHQDDVRPLVHITCRDHNLIGLQSHLMGLDALGIHDVLAVTGDPTKI
GDFPGATDVYDVSSLELFQLIKKLNEGISFSGRPLRKKANFSVAGAFNPNVRVVERAVKR
LEKKIECGADYFITQPVYTKEKIIEIHEAVKHLDTPIFIGIMPLTNIRNAEFLHHEVPGI
KLSDEVLERMRACGDDREASTAEGVQIARELIDTAASLFNGIYLITPFLRYDMTVELVHY
INQIDVAKEREVHHATSTN
>A0A8J3V2L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planotetraspora thailandica|TrEMBL
MALGLPSRLPERVPTVRELLAEGERSFSFEFMPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPRGGNPLDEWVKHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSTTIESDTEYFV
QKCRAGADYAITQMFFRAEDYLRLRDRVAAQGCDTPIIPGIMPVTQMSTIARSEQLSGAP
FPPEVAERFEAVADDPAAVRSLGIEHAAELCRTLLDEGAPGIHFITFNRSSATREVFQAL
APAGATTHR
>A0A076N202|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis methanolica 239|TrEMBL
MTSVIERLRGESPAFSIEFFPPRDAADEAVLWRSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGEWV
PHPQGLSYAEELVALVRSLGDFCVGVSAFPYGHPRSLDLDTDTKYLVRKFRAGADFGIAQ
LFFEAEDFLRLRDRVAAAGCDALVIPGVMPLTTPRTLHTTIRLSGAPAPQRLLDRLEPLA
DDPKAFRAEGLDVVTELCERLIAEGVPDLHFYTFNRSKATREVVHRLGLVPARA
>A0A3Q8GLC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurellaceae bacterium 12565|TrEMBL
MLWDSIDRLSPLKPKFVSVTYGANSGERDRTHSIVKSIQEKTGIISAPHLTGIDATPEEL
KVIAKDYWDSGIRRIVALRGDIPKGYDKALFYASDLVALLKSVADFDISVAAYPEVHPEA
KSAQADLLNLKRKIDAGANHVITQFFFDVESYLRFRDRCVSIGIDCEIVPGILPVTNFKQ
LQKMAAVTNVKIPTWMGKMYEGLDDDQTTRNLVAASIAMDMVKVLSREGVNDFHFYTLNR
SELTYAMCHTLGVRPDLTTA
>G2NGI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. (strain SirexAA-E / ActE)|TrEMBL
MTGAADEGLRAALTRSTPTFSFEFFPPRTAAGSRALWNAIRRIEPLAPDFVSITYGAGGS
SRDRTVEVVRRVVTETTLRPVAHLTAVGHSAAELRRVVGRYADAGVRDVLAVRGDPPGDP
RGAWSAHPDGFTHAYELVELIRSLGDFTIGVAAFPERHPRSTDWESDIRHFVAKCRAGAD
YAITQMFFDVEDYLRLRDRVTAAGCDIPIIPEIMPATDVRRISRFVELSGCAFPEDLAHA
LEAARDDPAAGHRVGVEHATAMAERLLAEGAPGLHFITLNSSTAATDIHRTVAPARPVPP
AGTGAVRGALPAGGAPVGLPGQA
>A0A1E4IL54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax sp. SCN 71-131|TrEMBL
MTSSQPISFEFFPPNTPVGSEKLKTVVAELAAVRPEFFSVTYGAGGATRDKTLAAVRAIA
AAGHEAAPHLSCVGATREGIAEILASYRGQGIRRIVALRGDLPSGTAVAGEFRFAADLVR
FIRQTQGADWHIEVAAYPEYHPEQRYARRDLQHFADKVAAGADAAITQFFFNPDAYFHFV
EEAQRLGVAVPIVPGIMPIHNYARIAQFAARDGIEIPRWVALKMEGFLDDAASIRAFGLD
VMTRLAERLLAGGAPGLHFYTLNQSALSLEICRRLGR
>A0A076H5H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. KORDI-100|TrEMBL
MTTALQRVLKAGKAAITAEVMPPRGADPGHTLAMATKLSGCVHAINVTDGSRAVMRMSSL
AVCRLLLDAGLEPVLQLACRDRNRIALQSDLLGAHALGIRNLLCLTGDPVKAGDQQTARQ
VNEYESVKLLRQVEAFNRGDDPNGGALADGPTDLFAGCAADPQSRSWSGLQRRLMRKRDA
GARFVQTQMVMDPQALERFQKDLAGPMELPVLAGVFLLKSAKNARFINRVVPGACIPEDL
IARLDRAENPAAEGVAIAAEQVGRYLDIVQGVHLMAIKAEERIPLILEMAGFSSLPV
>A0A495Q0A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gillisia mitskevichiae|TrEMBL
MKITEHIAAAKGKTLFSFEILPPLKGQNIQSIFDGIDPLMEFKPPFIDVTYHREEYVYIE
QPNGFLEKKVVRKRPGTVGICAAIQNKYGIDAVPHILCGGFTKEDTENFLIDLDFLGINN
VMALRGDAVKSETYFKPEPKGNCFASDLVSQIQEMNQGQYLDSPLEKNHATNFCVGVAGY
PEKHMEAPSLDNDIERLKAKVAAGAEYVVTQMFYDNSKFFEFVSKCRKSGITIPIIPGLK
PLATKKQLTNIPHRFHVDLPEELIRSVNNCKTDLEVREVGVEWCTAQSKELISSGVEVLH
YYSMGKSTNIHKIASSVF
>A0A0M4P0D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Hardjo str. Norma|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A3A1X0C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium NR047|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGILALRGDVIAGQEAAGVFEHASDL
VSYIRSKRPDLPILGACYPEK
>A0A564VTX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudocatenulatum|TrEMBL
MHSPMFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVS
EYGIPSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFEHASDLSV
YIRQQRPGMKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KARTAGIDVPIEAGIMPVMNVKSVLNMSSKCQSKIPEKLGIMLDKWGSDKALLKEAGIAY
ASEQICDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A124GRA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium freii|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKVLGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRETHGDYFCVGVAAYPEGHPADTFQDVQDPIRDIPY
LVEKTLAGADFIMTQLTYDIEAYQKFENALRSHASGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIARRMEELKHDDDAVKRAGVDIVSEIVGGMRDIPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPSYSDAGDIAIADDPASIPLDFPGRALRRRRASSINSQPHNRVIVDKL
SVHESSQDSVHEALADSAGVPAPPPNRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTANSARRLWGSPVDSKDMSTLFRRHVSGELHMVPWSEGGAEEDGDG
LNAETELIRPELLKLIDGRGWWTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFC
SSNDYTNILKPMFAKHGHDKLTWFATNIKGDFESSLPIQPADVELDDLGSNPESVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPSETYLDTTKNDSWLVCVV
GQQFGAGTKQGSKEEEDEVKWMWRVLAGEEA
>H0SUT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. STM 3809|TrEMBL
MTDLATAIADGHSAIIRPKISFEFFPPKTEEMDRTLWTSIERLAPLEPSFVSVTYGAGGS
TRERTHATIARILKETALLPAAHLTCVGASRGEIDEVVDRYHEVGVRHIVALRGDPPGGI
GTLYQAHAQGYQSSPELVAGIKKRHPDIEVTVSAYPEKHPESRDFDADIDMLQAKVDAGA
TRAITQVFFDNDVYFRYLDRVRARGITIPIVPGIMPMHNFKQARGFVTRNGTSVPDWLAE
KFEGLDDDPETRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPKSA
NKVAA
>A0A1G9WUI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter steynii|TrEMBL
MKIVDHISNAKGKPLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKIAYRKRPSTVATCAAIMNKYNVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDNSFIPTPDGHAYASELLQHVVDMNNGRYLHDYMEDAAKTDFCIGVAGY
PEKHYESPNLDTDFKYLKHKVDTGADFIVTQMFFDNKKYKALVDKCRANGINVPIIPGLK
PITSSKQLVSLPKIFHLDIPMELSEAIQACKSEKDVKEVGIEWMIHQCQELKEMGAPVLH
FYTMGNPEPTKKIVQAVF
>A0A3A1UN18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus nanensis|TrEMBL
MGDAAQHTRPNLREALAERILVGDGAMGTYLYQMGFPVGVSYEEFNVIRPDVIESVHRQY
YEAGARLIETNTFSANLEKLSKYGLENAMEAINREGVRIARRAVGDDAYVVGAIGSIRDG
KLKNVRTARVIDAYERQMKALIEEGVDGLLLETFYDLAEMKLALRIARELTDIPVICQFA
VEDVGRTQDGASLADAFAELQALGADVVGFNCRSGPNGIMRAIDSIQGPVSLPLSVFPNA
GIPDYVDGKYTYSAGPDYFAECARRFADRGARIIGGCCGTTPEHVAAMAASIADYVPQPG
AAEAAKRQASVVRESAVKPAESRMVTEHREPTIVDLAKQRHTVIVELDPPRDLDIRKFME
GAKALKDVKADAITMADNSLAVTRMSNLALAALLQDRIDIRPLVHIACRDRNLIGTQSHM
MGLDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGTAFSGKPLKQKA
KFVVGAAFNPNVKHLDKAVQRLEKKIASGADYIMTQPVYDPALIERIAESTKHLDVPIFI
GIMPLANGRNAEYLHNEVPGIQLSDEVRGRMAGLEGEAGRAEGVRIAQELLDTALQHFNG
IYLITPFMFYDMAVQLTQYVWEKTGR
>A0A7W4YCD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas cellasea|TrEMBL
MHVPVSATLGGARPADRPLMSAPVTDAAPAPTRSRDVRAAVDRPTVSFELFPPRNPDAAP
KLWATIQALGEARPDFVSVTYGASGKTRDTTRGLVRRLLRETSLNPIAHLTCVGTSRAEV
TAVVEEFLDEGVRSFLALRGDPPADQPDWRPHPEGLETASELVALLREIEERRCRASLAQ
KVRATVRPLSIAVAAFPRGNAGTGSTRAQDVAALLAKQEAGADFAITQVFFDAGSYLELV
AEAREAGVTIPIIPGIIPTTDPARLLRVEALTGVTVPRPLLDRLGSVDDDAERHRVGIRA
SVDLVNAVLDGGAPGVHVYTFNTHHAALDLLEGAHLGGGAPTAPDRAPGPQAGSPSPVPA
PTN
>A0A1C3TDT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRATLNVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKDAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7V1MKE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MYCIFGQVVNIIEALNKKERTFSFEFFPPRTPKGMVRMYKTARVFSELGADFFSVTYGAG
GSTSKSTLEIVKEFQGRFAKPAIHHYTCVKQSPNELRLTFDEMRRSDVRNILAMRGDPPK
DEPYYRPAKKKELKYGYELIEFIRKHYGDWFTIGVPGFPEGHILTPQKKLDSKYLKVKED
AGAEFVIT
>A0A1I8API1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steinernema glaseri|TrEMBL
MRTLEPIKHDDDAVRNYGTHLAIEMCRTILTEGLAPSLHMYTMNREGSCRNILQAIGLWT
QQPTRSLPWKPHGGHHPIRCKEDVRPIFWSARPKSYIFRTKDWDQYPNGRWGNSSSPAFN
DLQDYYLFYLKGTPTDVQMQNMYGKELNSIEDVQKVFVNFITQQENENGVKVTRLPWNEQ
ESGTQPETTLIKEQLLWCNQNGIFTINSQPAVNGAPSADPIVGWGKPGGYCYQKAYLEFF
LEKGVAQKLKTVCAEYPRLSYHMINYNNTVEWTNGDSTTPIAVTWGVFPGCEVAQPTVVD
PLSFRVWKDEAYDAWLTTWAAIYPEGSKSTKVLREVHDNYYLVTVVDNDFVKDTVIFEAL
EKAIAM
>D5X3Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomonas intermedia (strain K12)|TrEMBL
MRMASAQSVSPRANLSFEFFPPKTPEGADKLRAVRQRLYARQPEFCSVTFGAGGSTQEGT
LQTVRDILAEGVDAAPHLSCIGASRDSVRGHLRDFQAAGVKRLVALRGDLPSGYGIGGEF
HHARDLVAFIRAEMGSAFHIEVAAYPEMHPQARSPLDDLQHFADKVRAGANSAITQYFYS
AAAYRRFVDDVRALGLDVPVVPGIMPITNSSQLLRFSEVCGAEIPRWIRLRLQSYGDDRE
SIRAFGREVVSSLCEELIASGAPGLHFYTLNQAEATLAVLDDLGR
>A0A7R9A9K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Darwinula stevensoni|TrEMBL
MKRGPLFIDVTWHPAGNPAGDSETSSMSIASAALNYSGLETVLHLTCVKHTRTQISSYLE
RAHGLGIRNILALRGDPESRENVNATTDGFSHACDLVEHICQVHPNKFVIGVAGYPCGHP
DASSYEEDLLFLKKKVDAGAHFIITQLFFNPEHFIKFVQDCRAIGIQVPIIPGVMPIQSY
DSLRHIVNLSRLEVPKDMMEVIQPLKDNDEAIRNYGVDLAVSMIQRLFESDMAPGIHFYT
LNREVAVVKILKKVGLWRSGPSRSLPWKLAFNHRRSTEEVRPIFWSARPKSYIYRTQNWD
EFPNGRWGNSQSPAFGELKDYYLFYLKSKNSKEDQLAMWGSELTCEQDVWNVFYQYISGE
SNRKGITVTSIPWNDDELSPETILLKDRLVDLNKRGILTINSQPNVNGAPSEDPVVGWGM
PQGYVYQKAYLEFFTCRENVEALIQVLPKFPKINYHIINKSGKVNLANCHKHRPIAVTWG
VFPGSEIIQPTVVDPVSFKTWKDEAFELWNEQWGKLYPEGSYSRDIIRYISDNYFLVNLV
DNDYVKPESSLWMLFEAMFEQRSQNSKDSALASPTTN
>A0A6S6W2M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenophora teres f. teres|TrEMBL
MHISKKLAQAREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQTVYGLETCMHLTCTDMEKSKLDDALREAYQSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGGTF
IVTQMFYDVDLFLEWVGKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTRCNIPQHWTDAL
EPVKNDDVEVREVGKILVADMCRKLIAAGITHLHFYTMNLAQATRMVLEELDLLPDGEAP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNVKLWGTPMCIRDLSDLFVRYMEGKLDSLPWSEQAITTEAGPIRSDLID
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDFVDTWYLLNIVHNDFRETRGIFPIFDGLEVKDMDKPLYNPSVDL
PGVNGSEATNGTNVTNGEAEPHKKEAPGLIETAKAAAVEVTNGIKSLAVSN
>A0A1G8CLY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. YR213|TrEMBL
MGHLLMHPAQLRAAGNITHAYSLEVSAKDMSALNAAAPRIMPASTIAIPYLPREDNDARL
AAARTVRSLGFEPMLHLSARRIASLVEFESFIQRAVAEAGVERCFVIAGDPSTAMGPFSD
SAALIDTGIFERAGMQVIGVGGHPEGHPVMSTAEQWEVLERKCDSIGKRGMAPLIVTQFA
FDADIVLTWLKALRERGIDHPVRVGVPGPASIAVLARYAAMCGVSACASMWSKYGVSIGK
LFGTAGPDLFVDRLANGLTEAHGEVSLHFFPFGGIAQSVKWIEQYRARTGPGP
>A0A0N1A5L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. AAP43|TrEMBL
MTETAPAITGTKPPRISFEFFPPKSPDMADQLWQTVHALQPLAPDFVSVTYGAGGTTREP
TLDTVRRLIAETPMATAAHLTCVGATRDEVRAVVDEFKAVGVRHFVALRGDPQGGVGTRY
EPHPGGFENAAALVRGLRHMGDFEVSVSAYPEKHPESADAGADIDMLKRKVDAGATRALT
QFFFDNDIFERYLEQVRAAGITIPIVPGIMPIQNLTQLKRFAGMCGASVPEGFDLRFQST
EANPEARASVAADIAAEQIADLSQRGIEEFHIYTMNRAPLTLATLSRLGLYGARDLSGAA
A
>A0A0N0CNV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus apinorum|TrEMBL
MPLQYSFEITPNIDQDNLDGLLKLHPQFISITDRNHDVDNLVQSLKIADYVHAHSDVDVM
IHLTGIDKGYATVKQMVDLMITHNINDVLALRGDKLSQNDSAITFSHADELVAFIKQEYP
HVNISGTCYLNSSDEEMHWLRHKVSKGCANLISQFSFNVNDYVDYLNQTDVTTPIWFGIM
PVISKIQTQKMLDLTHATTSDKLNDLMNASEEKFGEKGVRYIVGMINKINQAGADHIHLY
SLNDAENIKKIIEQI
>A0A1B2CTU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MVRDLANRAGTGLPFIVSPPSSRRCATVAAGNVRRQPWGAAAAAPPISDAPGRADAEVRE
KSVPPHGDRAAVPPVPSVPVTRTVRELLSAERPTWSFEFFPPKTPEAEPQLWTALRQLER
LQPSFVSVTYGAGGSTREGTVSVTERIATETTMTPMAHLTAVNHSVSELRHVVSRLAAAG
VRNLLALRGDPPGADPQAAWSAHPAGLNYAAELVELIRSMGDFSVGVAAFPERHPQSPDF
ETDVARFVDKCRAGADFAITQMFFRAEDYLRLRDRVATRGCEVPIIAGVMPVTNARQITR
IVQLSGQAFPPELAHRFAELDGDRPEDRAAVRAYGVEVATELCRTLLAEGVPGIHFITMN
RSTATREVHANLVGANLAQVPARS
>A0A1A3KCJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium asiaticum|TrEMBL
MKVGCPKRMEFGPCGGVRPDGQCEMQAGACAFDDVVPWASPAPARRPARWQNSGPFVLTD
FSCAPFDRGDVAATAAILAPACDAVLVGEHQNKPDFPPTLMGSLLLDAGVVPWITLSCRD
RNRVVLEQELRGLRSIGVDTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGVTPA
VPETPTAPPVHARPARLVEKQRAGADVAVLNHVPYPRMIAEFMTAARSAGLSIPVIAAVA
VFTDSVSAAVLQGLPGLELDQAVTEQVLTATDPVAAGIAAAVAEARELISIEGVAGVNVS
GLASASGAHIGAEIKAEVGRRIREEAQ
>A0A4R1NDJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sodalis sp. 159R|TrEMBL
MSFFHANQREALNQNLAELQGDINVSFEFFPPRTSEMEQTLWHSIDRLSILKPTFVSVTY
GANSGERDRTHSIIKDIKERTGLDAAPHLTCIDATPEELKKIAEDYWHSGIRHIVALRGD
LPPGSGKPAMYAADLVTLLKKVGDFDISVAAYPEVHPEAKSAQSDLINLKKKVEAGANRA
ITQFFFDVESYLRFRDRCVAAGIETEIVPGILPVSNFKQLQRFAAMTNVKVPNWMTSMFD
GLDNDAETRKMVGASIAMDMVKILSREGVKDFHFYTLNRADLTYAICHTLGVRPQVAAEQ
TQV
>A0A660G1B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pasteurii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRAIAQDYWNSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A660UB57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MGADGSKNCRRSRSFTSSRGLKMEFKEKLKAGRFVILAEFNPPKGVDTKEFLENALILKG
RVDAILVTDMSGSIMRMSSICASRLLLEKGVTPIFQISSAHKNRLAIQGDLLGAYALGLT
NLFAIKGGDPSIGDHYEAKAVYDLQLMDLLDIIKRLQEGYDQAGADLVGAPQFCSGTIVN
AGVKEHVLDLEIMEMEEKVRKGVDYFITTPVFDHTAFTEFKKKISHFTVPVIASVIILKS
AGMARYINKHMEGVKVPDSTINRIIQSPDKMKVSVEIASELIKGLKEFCQGVLIIPIGWE
TRIPQILDSSAL
>A0A1F6E121|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kaiserbacteria bacterium RIFCSPHIGHO2_02_FULL_59_21|TrEMBL
MKVTDLIKHSTKPFTSIEIIPPKKGTRMETLFGELEGLMRYKPAFMSVTSHAHERTIEEV
NGKKIERIKNKRLDTNAICIAAQSRFGVVPTPHVICRGFTKDETEDMLLTLRFHGLENVL
ALRGDGPPNDGEFANIYASDLVEQMQRMNRGEYLDPMENADKTDFCIGVAGYPEKHFEAP
DFDTDLKNLKKKIDAGSHFIITQMFFDNTAFYSFRDEIARRGINVPVIPGIKPLYKKQHL
EALPRIFYTKIPQAVQDSINRFEKEEDIYRAGIDSTIAQCKDLLAHGVPGIHFYSMSVAK
PTSDVLEGLK
>K1ZJ50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MKYCQNIDISFEVFPAKSPDEFYKIHPVCAALNQFNPDYFSVTFGAGGSFQCKTQQLVRE
LVNAQLTITPHISCVEMTKQRLSDILAEYKGLNIHHLVVIQGDLPPEGEHKGDFHYAHEL
VEYIRKISGNYFFISVAAYPEYHPRAVNSLTDLKNFKNKLEAGANNAITQYFFNTDAYFR
FLEACEKIGVTAPIIPGIMPIHDYHKLVRFSNACGAEIPLWLRKQLEVYVDDPVSFKKIG
IEIVTKLCERLLSEGVNALHFYTLNQIEPTATIIKHLQLPEKNRLSAAVS
>R9GZR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides thetaiotaomicron dnLKV9|TrEMBL
MRVIDLIHNSEKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLFWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEVLKCKNDKEAEQVGIEWCAAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A660UCY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MKAGSRLEKILEQGNFAVTGELGPPKGNDLEVVKRKAELLRGKVDAINVTDNQTSIVRMS
SIATSTILVQLGLEPVMQMVARDRNRIAMQSDIFGATALGIKNMLCLSGDHQTFGNQKGA
ANVFDIDSIQMISMVKGLRDDGVILGGDDKVEGDIKIFIGAAANPFAEPFEFRVVRLAKK
VKAGVDFIQTQCIYDMKRFKKWMEMVRDRGLHEKCHILAGVTPLKSGGMARYMAKNVAGI
IIPDEIIDRMVKAPSGKAADEGIKICVEQIQELKEIEGVHGVHIMAIEWEQMVARIVEEA
GLLPRPEV
>A0A8J6NB14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfobia pelagia|TrEMBL
MKADFKEYIREHVLLGDGAFGSYLYEKGIDLGKNIDLLNVKNPDLIFSIHEEYIRAGSQL
IETNTFGGNRFNLQELGKEDQVREINLAGVRLARKAAGHDVYVAGSVGPTGIEFPLVSEE
VTEGEMNEAFSEQIGALVEGGVDIIILETFTHLEEILMALGVARKLSDLPIIAQMVYPSK
GKTARGITAYDCARELLAAGASVVGTNCGRGIDPMLTAIESMAPLAESQVPLSAFPNAGL
PEVIGHRMIYPAQPAYMAKRAAEMIKMGVRIIGGCCGTVPAHIHEFRSSLKLRHKKTLRS
GPVHIETSESVSPQAPIVATGTGGFLEQVQKDQMPVIVELDPPTHLEIDNVLEGAKFLAE
SGADAVSLGENPLAILRAGNIALAHRIKEEVGVQVILHQTCRDQNGLGLQSHIMAAHILG
IEAILAVTGDSASSTDQPGVNGVFDTNSFGLIRMLSRFNQGVNMAGKPVKQKTRFSIGCA
FSFRPTSPKMQISRLEKKAAQGAHFVMTQPLFDKNEVEKMVELTSHLDMAIFPGIFPLIS
ARNADFIHNEVPGITVPKAVREVLWRYADVADQRKAAMDITARLVEDISSFVDGIYLVSP
LNKWDIAGRFVRQIRDAGWTGSGKLSKRTSGSFPAS
>A0A7W5Q118|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK313|TrEMBL
MSSKTENGQRGIRISFEFFPPKSEEAEAQLWNTVADLTEWQPEFVSVTYGAGGSTKAPTL
SAVRRMIHETPFTTASHLTCVGATREDTHRVIDDFLAAGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVSALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGANRALTQF
FFDNDAFERYHDRVRAVGVKIPVVPGIMPIQNLTQLKRFAGACGTSIPSWLDERFDGLDE
LADKRASVAADVAAEQIEDLVRRGIHEFHLYTMNRSPLVSAVLERLGIRRKADARAGAAA
>A0A7M1SVS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruania alkalisoli|TrEMBL
MTTATLYRSPRATPSVSFELYPPRTPRGRETIGRTIGALASQIPDYFSITYGASGSTRTT
SRELICRVLDDTPVTPLAHLTCVGASAEDLSEYVATLLEAGVRDFLALRGDPPAGEPDWQ
PHPQGLTRASELVHLLRQTAREHLGDEGDEVSISVATYPGGAYADDGTPMIARDDVAALL
EKQAAGADFAITQLFYDARHYAELVRQARAAGVHIPIVPGVLPLTDPNRLRRMVELTGVP
VPPDLLDHLDSAADKDEAYQRGLAASVRLVHEVVETGAPGIHFYTFNSSRAVLDLLRESG
LR
>A0A6H9YJQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura rudentiformis|TrEMBL
MRHGRPDRAPTIRELLAQGGRSFSFEFFPPKTDKGVRSLWRTIRELESLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAVGVRNILALRGDPP
GDPMGEWIKHPEGVEYAAELVKMIRSYGDFCVGVAAFPYKHPRSRDIESDTRYFVEKCRA
GADYAITQMFFRAEDYFRLRDRVAAHGCDVPILPGIMPVTQMSTIERSEQLSGAPFPPEV
RARFEAVADDPEAVRRLGIEHAAEVCRELLEQDAPGIHFITFNKSTATREVYGLLGAAAY
GASGNAAPMTA
>A0A834JBZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vespula vulgaris|TrEMBL
MRSFVAGIKVMLEGKINNDDDCKITKDCQLNRRTNELVHLQQVINEKINKKEVFYSFELF
PMKGSSDIYKRFFAEMDKYSPLFYALTWHTKGLINSYLSLDIVEQFPSRTLLHVAAKGLK
RSNVEMILKRAYNLGIRNIFALQGDSILEDGDFPHAIDLVKFIRSCFGKKFSICVAGYPD
MHPLSPNKDFDLFYLKAKVDAGADFIITQIFFESDTFINFVNDCKNIGITIPIIPGIFPI
PEYKCLQRMTNICRLHIPKKIVDRLETIKDDDEAVKNFGIEFAIDLIKDILESRASYGFH
LFTLNKIPMAQNICNQLNLTYQLHSEQL
>A0A0S2E3Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter antibioticus|TrEMBL
MLPISFEFYPPKTDEQRTQLDRSAAKLKPYSPNYVSCTFGAGGSTLSYTPDTIQRLREKH
RLDAAPHLSCVGGTRAEIRELLARYRELGCRRLVTLRGDLPSGMASAGDLRYANELVEFI
RAETGDHFHIEVAAYPETHPQARDALSDLENFKRKVRAGADGAITQYFYNPDAYFRFVDD
VRAAGIDIPIVPGIMPISNFSQLRRFSDLCGAEIPRWIGQRMQAYGDDADSVREFGADVV
AQLCSRLIEGGAPGLHFYTLNLAKPTLTVLSRIA
>A0A511AFU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium aerolatum|TrEMBL
MPPESATLDSSRVPFSFELYPPRSASGEDALHETIRRLADAGPDFISVTYGAGGSTGGRS
LEVLRFIRENTYVEPLAHLTCVGNTYAGAAALIREFLDAGILSFLALRGDPPAGQTEPFL
GDLETSAQLVQLIGRVQAECAPYEETPIPGLPGAARITSRRHVNIAVAAFPKGHPRATHR
TQDVEALLAKQAAGATFAITQLFFHPDDYSAFVERARAAGVTIPILPGIMPITSPARLAR
VLELTGEDLPSELAIALEIEPTAEGRREIGIEWAARLTREVVAAGAPGVHLYAFNQHDTV
LTVLAEAGLLPALRS
>A0A2K2FR04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoclostridium thermosuccinogenes|TrEMBL
MQHHIKNKIYHVEILPPKQDTEKLEADLELFANKYNRVLESGYCACITDNAMGHLSFQGT
EMIEELGLEVRPEQVMIHLNTFHTKEDLHKILDTCKSLGIKYLLVISGDGSERLPKLRPS
DIGVEGVVESVTSVELLKYIKEQYPDTFVLGVAFNPYEPPEHEFEKLERKLKAGASFIVT
QPIIEKNKMVDELLEKHPDIPVIVEAWMSKKLYLLSDAVGYEIPQDTEYDPIETLKMLHK
LYPGCGVYLALLGFKTQYHLLENTWL
>A0A1W2LXE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis keratiniphila subsp. keratiniphila|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTPRTLHTSIKLSGAPAPRRLLDRLEPLA
DDPKAFRAAGIDAVTELGERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A0R3LLC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium valentinum|TrEMBL
MELRDHFAAGTDVTITFLPGDNYRHNVETAAALRRAGYNPVPHIAAREMASREALGDFLA
RARGEADVSRILLIAGDVAAAKGPFKSTRDVCSSGLIEAHGIASVSVAGHPEGHPYLELP
DALQGLTAWRDWGQRTGTRVDVVTQFCFESAPILQWIGALDRAGIDLPVIIGLAGPATPA
TLTKFALRCGIGNSMRALRAQIGRFGRLLTDTGPDDVVRGLRCAPAAATAPIAGFHLFPF
GGLRKASNWLRDYDRNLLRPAERVATSRAGFQNP
>A0A1H8GTT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachymonas denitrificans DSM 15123|TrEMBL
MTAPSISFEFFPPKTPEGAEKLRTVRQKLYACKPEFCSVTYGAGGSTQKGTFDTVQEILQ
EGMEAASHFSCVGATQASVREQLETLRQMGVKRLVALRGDLPSGHGLGGEFMHASDLVSF
IRVETGDYFHIEVAAYPEVHPQARSPEADLRALKAKVDAGANGVITQYFFNADAYFRLVD
DAATLGVSAPIVPGIMPITSSSQLIRFSDACGAEIPRWIRLRLQSYGDDVDSIKAFGHEV
VADLCERLVEGGAPALHFYTMNQAAPTLALCERLGLNVAEPAVA
>A0A1S7NUN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium tumefaciens str. Kerr 14|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNAEMETQLWETVAELKKWDPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLSTAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYQ
PHPEGYENAAALVKGLREIGDFEISVSAYPEKHPESASDAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A3G8M893|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystis rosea|TrEMBL
MFNALHPTASPNQFAISYEFFPPKTPEMETQLWQTINRLAALRPHFVSVTYGAGGTTRER
THSIVARIVRETEMKPAAHLTCVSAAREDIDAILRDYWDAGVRHIVALRGDPPTGVGSRF
EAHPKGYAHSTDLVRGIRRIGDFEISVSTYPEGHPESASIEQDLDALQAKVDAGATRAIT
QFFFDNDVYFKFLDKARGRGITIPIVPGIMPIRNFKQVAGFAQKAGASVPRWLAERFDGL
DEDPETRALIAATTAVEQVMSLARAGVNEFHFYTNNRADLVFAICHLLGVRPLREKALA
>A0A2K2FKM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoclostridium thermosuccinogenes|TrEMBL
MKIVKLFKNKRPVVSFEVFPPKPDVPIENIYDSLDKFKDLNPDYISVTYGAGGSTRGRTV
EIASKIKNELGIESMAHFTCVGHTKEEICALLDQMRSHKLENILALRGDPPLNQPDFDFS
KNPYRYANELIREIKVKNGFCIAAAAYVEGHVESARIKDDLINLKRKVDEGADFLITQLF
FDNRMFYDFLDKLISLNINCPVTAGIMPVLKADQLKVIAAKSGCSIPARLVLLMDKYADN
PEDLRKAGIEYSAAQIRDLVENGVDGIHLYTMNRPKSTRKILEQAGLLYRMHQEAYVSKQ
LSSFPLF
>A0A423P9C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A3E1IX02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNAAGVFNHASDL
VSYIRSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A814ZZJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria magnacalcarata|TrEMBL
MPDNGINIKTICNSSNDSVDLKRSESENGIGTTKGSSPQPVKYVSLAEKIQERISNHERW
FSLEFFPPTTSNAAANLIGCVERMAMAQPLFCDITWRSTGDPAGNKETSSMMIANTMLNY
CNIDTMLHITCCGTKKPQMVQYLNRAKEVGIRNLLALRGDPPVGEQWDPDQTDFRYATDL
VKFIREKFGDYFVICVAGYPQGHPDTESYEEDLGYLKQKVDAGADFIITQLFFQAETFIK
FEADCRAIGITCPIIPGIFPIQGHASFRSVIRLAKLDVPQEMLDSIESMRDNDEAIRDYG
VQACVDLCQKLLDSGKVLGIHFYTLNREYATTEILKTLSFWLEETPLRALPWKKTSQSHT
RSQENVRPIFWSLRPKSYIHRTTDWNEFPNGRWGFSFAPSFGALTDYHLFYMKMDASHDA
LLDEWGHSLTSEEDVWKMFACYISGEKNVLGKSVRHFPWKDEEVSLETNLIQSQLVEYNR
KGILTINSQPPVNGKPSSDPIVGWGVPNGYVYQKAYLEFFTSASNIPALRAVLKNFPNIN
YHFVNKSGEVNETNADGEQATALTWGVFPGKEIIQPTVVDPVSFMIWKDEAFSLWMERWG
KLYEPGSPSYSIIDEVSNTYFLVNLVDNDYPQGSCLWKVLDAMLEYQKSTSQDVKS
>A0A397C6V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces astaci|TrEMBL
MGKIIDRLTELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPREQLREILKNVRAAGIRNILALRGDPPIGSE
RWKAIPGGFQNAVELIRFIREEHGDWFCIAAAGYAEVHTEAWNNPNLPPSDQVRRVDMLR
LKEKQDAGADFIITQFFFDVDNVPPQVEDALVTIKNDDSAVKKYGIQLAVDTCRKLLANN
LSLHFYTMNLATTVRTVLEGLHLIERERGLPWGAPITRSKDGTLEKSIEQLPWCEQGLSG
ESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPHLM
QRLVVRDIFKIFARVITESMTKDDLRQRVLELEGKNEKLHETVAKLKIIQAEANRELKDL
HGDLSTSREENSRLKAQVRELRSRLAMAEL
>A0A0C4E4I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnaporthiopsis poae (strain ATCC 64411 / 73-15)|TrEMBL
MDKITDKIAALPADATYFSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
SQKSLELAEICQRELALTTCLHLTCTNMSRRLLDKALDDARALGIRNILALRGDPPRPGE
YGEPEGSEPADTAFTWAVDLVRYIKQRHGDYFCIGVAAYPEGHADESHPTNQSLEHDLPY
LVEKTQAGADFIMTQLFFDIDAYDSFEKTLREHPSGAFAKIPIIPGLMPIQNYQMIKRTT
KLSHAKIPNPLMARLDAVKKDDEQVKKVGVDIVSELVEKVKEVKSRTPGPRGFHFYTLNL
EKAVSFIVERTNLIPPSGPGEDDAVFADETAIVADDASAAPPPSLLGVPAIHVNGTTPSH
HSMQGHHSFSSRRQSSIGSDPRNRVIVSGRPASHPDYEATALEASVPAEPINTRANTLAI
SEGEGVLGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSGTQAVELWGRPIEARDVG
ALFTRHLGGELSAIPWSEEEFNPETATIRAPLLALNERGWWTVASQPAVNGLASDHPTFG
WGPPHGYVFQKAFRLLRGTEDDRDSVCFYASNAAGDFVSSDATGGLRDHGQGRTAGTNAV
TWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWAEWAKVYGKGSPSEVLLESLRADLWLVN
IIHHDYVQPNALWDLLINQ
>A0A085RGA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cholerae|TrEMBL
MGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQNIVALRGDI
PAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPNWMVKQFEG
LEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A3L8A4Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides acidifaciens|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESAFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSNTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMVPKTFKVDLPEELVKEALKCKNDAEAEQVGIEWCVSQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A6C7UQB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKITSILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IQKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVNAGTDKLITQLFYNNEDFYTFKQNC
ALANINVPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAV
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEEIRA
>A7VPD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] leptum DSM 753|TrEMBL
MNLDTLLKQKRPVITDGAMGTYFTQKTGFSIHECEWANISRPELISEIHREYVKAGAQFL
RTNTFSANTKSLGRPLADVLEIVRAGYRLAKEAAGCQAVAAADMTAIYPRGDEETDLLPE
YLAIADAFLSEGAEVFLFETLTELSPFDQIADYLKKKKPECKVLISFTVSPEGITRLGVP
LRRLLDEVKPHRELFDGIGLNCGCGPAHILKFARELLSYSRQYLSLPVLVMPNAGYPAME
ENRTVFDTSPEYFSHQAVRIAELGVDMIGGCCGTTPKHLQLLSRLIQKKREPLAAVTTTV
TAVGSLEKSAPQESRFAQKLRKGDFVMAAELDPPYGSRVDKLLTACRVLQNSGVDIVTIS
DSPMARVKLDPVVCGAKLQRETGMEVLPHFCCRDRNVNALRAMLLGAQCENIRTILAVTG
DHVPELDRGYIKPVFNVTSAKLMEMISQMNQDVFADSPFTIGGAFNPNVANPKAELARLE
KKLKAGAVFFLTQPVFDEGRISTVKEAREMGAKMLLGIMPLVSYRNAVYMNNEVPGIQIP
TAYVNRFSPEMSREEAQRTGIEIALEIAESLRPHADGFYFMTPFNRAEIVAELIEKCREM
>A0A7V4NF53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium pennivorans|TrEMBL
MKVTEMVREKRIISIEIIPPKRGEDVENIYRTLDKLMNYDISFINITRHPVEVDYIEYEG
RIIKVHKVKRPGTIGLTAALMNRYRIDVVPHLVCVGMSKFEMEDMLIDLDIMGVDNVFVI
RGETASSVEKSNKGDYKYAVDLVEQIKDLNMGKYLYTEAKPTNFCVGVAGYPEKHYESPN
METDLKFLKQKVDAGADYIITQMVFDADIYKNFVERCRSIGINVPIIPGVKPVVSKNSVF
NIPKKFFVTIPQRFVEAIDNAKTKEEEFNVGIRFTVELVEKLIEYGAPGIHIFTMGRGEE
SCEVIKHTQSILK
>A0A4S9T7C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDHDTPVANGNGDKKAKARRRSSIANS
APQNRVVIDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVE
FFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLL
EA
>A0A454H362|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTNRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A7V8A8C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium|TrEMBL
MNTPIISFEFFPPKTEAMEEKLWDSVKQLAPFNPDFVSVTYGAGGSTRERTHRTVKRILD
ETTLRPVAHLTCVDASKDQVDEVLREYWASGVKSIVALRGDPPTGVGTKFVANADGYQNA
TEVVRAAKKIADFDISVSFYPEKHPESPNLMHDIDVLKAKIDEGASRAISQFFCEPDKYL
RFRDLAVKNGINIPLLPGIMPVGSVKGYMRMAAGCNTDVPQWFIDAFEGLDDNPEVRDLV
AASVASDLCTKLQAEGVNHFHFYTLNKAGLASATCRRLGVKLGVKP
>A0A7Y2AZ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MLKAWTPLSFEFFPPRSDEQQQRFEAAWRELAALKPEYFSVTFGAGGSSLDATHKAVMGL
QANSGVPVAPHVSCKVDSREALAGYLDDYAKAGVRRLVLLRGDRQADGAEEGPFCYANEL
VSFVREHCGDRFSIEVACYPEFHPESASPGAELKYFRRKVDAGATGAITQYFYNADSYFR
FIDDCQKAGITIPIRPGILPITNYRQLSRFSEQCGAEIPQWILKRLEAYGEDRESIRAFG
LEVVTDLCSRLLRGGAPGLHIYSLNQSDPSLRLIQRLTKD
>A0A4Q8S666|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella hadar|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2S0WKV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium chenweiae|TrEMBL
MRHEATSLVAALRAPSPTCSFEFFPPKDDEGEAVLWQTIADLEPLQPTFVSVTYGAGGTS
QERTVRITGRIAGQTSMRPVGHLTLVGQTRGEIETVLKQYAAAGVDNVLALRGDPKGGPR
APWEPHPDGMTYAIDLVELAADLGGFEIGVAAFPEGHPDAESIEHDAEILVAKANAGAQY
AITQLFFRAEDYFGLVERVRARGCDIPIVPGIMPILNFAQVARMAELSGAEMPREVLEQI
EPIQEDKAAVRAKGIELATQLCRDLLAGGAPGLHFITLNRSKATREIFEALRADGLV
>A0A120FA14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora rifamycinica|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTAQGEQLLWQTIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVR
GDPPGDPGGEWIRHPEGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSVDVESDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFARVADDPEAVRRLGIEQASEMCARLLDEGVPGIHFITLNRSPATREVWRSLR
ADARV
>A0A7V0QZ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MKISEIFKKRDKGISFEFFPPKTEEGKKQLLTVAKELSTFDPMYASVTYGAGGTTQERTR
DVLYMLKEETGLTLMSHLTCIGATAESMDSLLNDYKEHGIDNILALRGDPPPDVPDFDPT
KGEFSYAVDLVKFIKKYDYFSISVAVYPEVHQEATSAEADLEYAKQKIDAGADFGISQMF
FDSRYFLDFLDRAYKKGINIPILPGIMPITDLNKIRKFASFCKATIPKEVEDRMSGILDK
PDEMQRVGIDLAVQQCEDLLDNGVKYLHFYTMNKSEVVIKIIEALKERLG
>A0A6L8HBI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTGLGAGNAQGNRRSAGARPGLTARLTQPGPMAAVELRPPRRGLDTARSMDFWIDMYHAV
QRFARQGTFVLLTDDAAGDAEEESLAHLAANLGDGSDFGTVVPFLTCKHPLEYCRMFARR
AAALGTAGVAVVGGDHSVGPERCVPHGKDLRAVLREDQPGFPLGGWANPHRDPVEQARFV
AADDFGADFVLTQIVSHHSLGRVARFRAELDRLGVDLPVVYGVFLYRSANPRTLRYLDRY
FPVPAREVTAEFAAGLSADEICARSVRRLGEAGAEKVYVSNLRSRDAARRLGEVVGG
>A0A8H6PZW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus hiratsukae|TrEMBL
MEKITDKIAALPPDENYFSLEFFPPKTQMGFANLTARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCLGVAAYPEGHPVDSYQDVQDPVRDLPYL
VEKTLAGADFIMTQLTYDIDAYTKFEEMLRNHESGAFKTIPIIPGLMPIHSYKILTRTTK
LSHVQIPPQIMSKLEAVKHDDDAVKRIGVDVLCDLVEAIKKIPCPGFRGFHFYTLNLEKT
VSFIIEHCGLIPDDPEDSGAVADDDYATASNGAQIRSLDRRRASSINSQPHNRVIVDRLQ
IPSDRSSRASTTHEVPATSAGMPAMPPDRNTTLQISEGHGALGREATWDDFPNGRWGDAR
SPAFGEIDGYGPSLHVSATVARRVWGYPVSREDISTLFRRHVSGDLYIVPWSEGGAEENS
SGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEF
FCPTKDFQTVLKPLFAKHGHEKLAWFATNAKGEFESSLPADPADADTIEMNPNNVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAYRIWDEWRRVYPRGTPTERFLDEVKNDVWLVCVV
GQDFGAGTENGSEEEQHETKWMWNVLINGQ
>A0A1Y4JIN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides clarus|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESAFTPEGNGYHHAIELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTKEVLKCKNDAEAQQVGIEWCVQQCRELMEHRIPSIHF
YSIGAVDSIREVAKQIY
>A0A0P9ZVZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. solidagae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSTEDLRKLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VKFIREETGSHFHIEVAAYPEMHPQARNFEDDLQHFVNKANAGADSAITQYFFNADSYFT
FVERVEKLGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLQLPR
>A0A170SK54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermococcus chitonophagus|TrEMBL
MRVTGCPKDLLNGPCGGALGGVCEVDGRRCPWFSVMERFELLDGAPLLVEHPVVVEMERK
YRGDVRIKESEFMKNLEKGKAIAVEFPIRLFERGERKFRRIGDIYTVPDNPLGYPHVSPT
SLATWLKTHGFSVMPHLTAKDRNVVAISSEFRTALEFGFEGVLITTGDWPGFIIQSKPVF
DLDSPNMIKLARLMFSGVMPTGEYVEVRERPFVAGTMNPNYPERVEGKRFARKIIAGADL
VFTQVVASVEAVRRIPRIIEESKKYAPGEVPVVVSLLYPLTKELESTLRKMGIETGSSFQ
EIVEEVSSLELGGINLIVFEEALWNEKLDEAFEILKSTL
>A0A6L8BDT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTNKGIQVSFEFFPPATANMERVLWASVERLEPLGPRFVSVTYGADGSTRDRTHRIVQRI
RNETGLTCAPHLTCVGSRREEVLAIAREYWDAGIRHMVALRGDPPQGSTGYVPCEGGFAY
ASDLVEGLLTVGRFDISVAAYPEVHPEASSASADLDNLKRKIDAGGTRAITQFFYDTAVY
LRFRDRCRGAGVKVPVVPGILPIAGFRGMLRFAAKCGVNVPGRIHERFTGLEDDPETSRM
IAASVAIEQVDELYRHGVREFHFYTLNRAELTYAICHALGLRPGGSRAEHAA
>A0A3M6AE82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>A0A062U184|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas pacifica|TrEMBL
MSPLSSTVKGEAPSVSFEFFPPKTETMANRLWDTVERLQPMAPDFVSVTYGAGGSTRERT
HDTVRRIAQETSLSPAGHLTCVGATKEEVLSVAEDYWDAGVKHIVALRGDPPAGMGEKFE
QYPGGFRDSIDLIQGIREHRPELGRCFEISVSCYPELHPESQGWDAEIAFLKAKQDAGAD
RAITQFFFEPQVYLNFLEKARAGGVTMPIVPGIMLQPNFKGLKRIAALCGSSLPDWLHEL
YEGLDEDEETRELVTANVAADLCRQLSDEGVSNFHFYTLNRAGLALSTCRLLGLKPNSAK
AA
>A0A0F7KAS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas communis|TrEMBL
MKSQKAFSPTFSFELFPPQTPEGVEKLRAARHQLSQFKPKFFSVTFGAGGSTRDRTFDTV
SEMLAEGHPVAPHLSCIGSTRENIYSILRKYQESGIRHIVALRGDLPSGMAQPGEFRYAN
ELVTFIRKEFGNTFEMDVAAYPEYHPQSRSAQEDFRNFRNKIEAGADSAITQFFYNADAY
FHFVDMCETANLNVPIVPGIMPINKFSQLVRFADNCGTEIPRWIRKKLEGYGDDIASIHA
FGLDVVTDLCERLLKAGAPGLHFYTLNSAFLTTKIWQRLGL
>A0A5H7NGA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Durham|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3R6ELQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHTHATDLLKQVNQFNDGFFFDGIPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDEDAKQLGIEWTTAQVQDLFEHGYNNVH
FFTVSAVDSVKQIAKILF
>A0A3E5AF24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHAHATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDDDAKQLGIEWTTAQVQDLFEHGYNNVH
FFTVSAVDSVKQIAKILF
>A0A4P9TAG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A024UV44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces invadans|TrEMBL
MGKIIDRLMELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPRDQLREILKNVRAAGIRNILALRGDPPIGSE
RWKPVPGGFHNAVELIRFIREEHGDWFCIAAAGYSEVHSEAWNNPNLPPSDQARQLDMIR
LKEKQDAGADFIITQFFFDVDKLLQWIRDCRQLGISIPILPGYLPIQTHNSFLKFTNWCK
TSVPPQVQEALVSIKNDDAAVKKYGIQLAVDTCKKLIANKLSLHFYTMNLARTVRAVLEG
LHLIERERGLPWGAPIMRNKDGSLEKSIEQVRPIFWSNRASSYIARTSEWDDFPNGRWGD
RTSPAYGELSEYYLAYKRPKVARDQLWGRPQTEEDVWNVFVKFIEGSVKQLPWCEQGLSG
ESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPRLM
QRLVVC
>A0A3D1DQA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MLTLGEIYSGQSTAISVEIFPPKTSDGDQALFDTLDRLAVFQPDFVSCTYGAGGSTRDRT
MELCREIQSRYQLATTAHLTCVGSTRDDLVEWISRVQAAGIGNIMALRGDPPRGDGTFSA
VAGGLEHANQLVELIRGVSSELGVGVAGYPEVHPEAADAISDLENLKRKVDAGADAVFTQ
LFYINDSFLQFRDRCQASGISVPVVPGIMPVTEFSRIQRIATLCGAKIPGELADRLEAVQ
DDRDAQLAVGVEYAVKQCRELIDAGVPGIHFYALNRSQACARILEALGWNTSSESSGEW
>A0A3Q9KWR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseoviridis|TrEMBL
MALGTASTRTDHARTVRDMLAAGETTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATERIAADSTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPEGLTYAAELVSLIKESGDFCVGVAAFPERHPRSPDWDSDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPQLSNAAV
PSVLKERILTAKDDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHPPRA
>A0A3G7UHF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas synxantha|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKIPAAPHLSCVGDSKNDLRGLLTHYQQAGIQRIVALRGDLPSGMGMASGELRYANEL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A6B1UE34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bittarella massiliensis|TrEMBL
MNLCDLFQQKKCVLSFEVFPPKKSSGVESIYRTLDELCALKPDFISVTFGAGGTGVKDNL
TVELAGAIRARGVEPLAHLTCINSDEETLLGLLDRLEEAGVRNILALRGDRVEGAEEGPY
RHANELMERIARRGGFNLVGACYPECHCEAPDPLHDLQNLRRKQEAGATHLITQLFFDNR
CFYDFAEKARIAGVHLPIEAGIMPIVNKRQIERIVTLCGASIPPKFARMLSRFEGDPAAL
RDAGIAYATEQIIDLIGSGVEGIHIYTMNNPAVARRICENIATALDCVNGGGAA
>A0A0M6WAP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia inulinivorans|TrEMBL
MRLTELLNKDEVTISCELFPPKQGAQLENYKNIVKDMAALKPAYMSVTYGATGGTSDYTV
KLAEEVRNNNIPALAHLTCASSTREKVASVIEELKAANIENILALRGDIPANADFPLPDQ
YKHASELIADIKAQGDFCIGGACYPEGHPEAATIFEDLDHLKEKVDAGCEFLTTQMFFDN
NILYNFMYKALKKGIDVPIVAGIMPVTNASQIKRITSLSGNMVPPRFLAIVDRFGDNPAA
MRQAGIAYATEQIIDLIANGVNHVHIYTMNKPDVAGEILDNLSNIYVR
>A0A5C7A622|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mitsuaria sp. TWR114|TrEMBL
MTTPVSIEFFPPNTPVGTEKLKTVVQELRAVNPQYFSVTYGAGGSTREKTLSTVADIASQ
GFDAAPHLSCVGSTRENIAEILATYRAQDIRRVVALRGDLPSGTATAGEFRYAAELVRFI
RETQGEDWDIEVAAYPEYHPQQRYAARDLQFFADKVRAGASGAITQFFYNPDAYFHFVEA
SRALGVEVPIVPGVMPINNYARIAQFAQRDGIEIPRWVALKMEGYMDDAASVRAFGLDVV
TRLCERLIAGGVPGLHFYTLNQSALTLELCKRLGLAAQA
>A0A061ILA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cricetulus griseus|TrEMBL
MNHQEAKVLPAGHRYPSLGMWASEAGCVRLSVPPSISRNPTMVNEGSGSGSGSGSGSESS
KDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRFDRMAAG
GPLFLDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETVLHVTCCQQRQEEITGHLHKAK
QLGLKNIMALRGDPVGDHWETEEGGFSYATDLVKHIRSEFGDYFDICVAGYPKGHPEAES
FEEDLKHLKEKVSAGADFIITQLFFEANTFLSFVKACTEIGISCPILPGIFPIQGYTSLR
QLVKLSKLEVPQNIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNRE
VATMEVLKQLGMWTEDPRRPLPWAVSAHPKRREEYVRPIFWASRPKSYIYRTQDWDEFPN
GRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFKVFERYLSGEPNQH
GYTVTCLPWNDDPLAAETSLMKEELLRVNRLGILTINSQPNVNGKPSSDPVVGWGPSGGY
VFQKAYLEFFTSREIVEALLQVLKKYELRVNFHIVDVQGKNITNAPELQPNAVTWGIFPG
REIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEF
LLDNCLWQVVEDTFELLNGHSVKGDAQAP
>A0A6P1INC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp. PBL-H3|TrEMBL
MGLPVSFEFFPPKTPEGVEKLRAVRQQLYALRPEFCSVTYGAGGSTQEGTFNTVRDILAE
SVPAASHFSCIGATKASVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLVAFI
RAETGDDFHIEVAAYPEVHPQAKSPESDLQAYATKVRAGAHSAITQYFFNSDAYFRFVDD
AYKLGADVPVVPGIMPITSSTQLMRFSDASGAEIPRWIRLRLQAFGDDTASIKAFGLDVV
TDLCDQLRNGGVPALHFYTMNQSAATLEIAKRLQLS
>A0A7R9LIJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oppiella nova|TrEMBL
MTEEWSVCETRYVPLIERIIRRQRSSSAPFFSFEFFPPKTKEAAINLISRLDRFRQSDPL
FCDITWHSAGNPGSDCETSSITIAGVALNYCGLETMLHITCVGLTRNELTNHLERAKTLG
IRNILALRGDQTYGETTGGEFRFASDLVRYIRQEYGNYFTIAVAGYPGSHPESESQEMDL
KYLKEKVDAGADFIITQLFFKAQVFIDFVQKCRRIGIGVPVLAGIMPIQSYDSLEKIVKL
SKLDIPDAIVSDLNAIRNNDEAVRNYGIDWTVSLCRQIIAANVTPGLHFYTLNRELATTS
ILKQLGLWTKCMKPLPWLPAANHKRCAEDVRPIFWSVRPKSYVYRTQTWDEFPNGRWGRG
DSPAFTDLKDYYLFLEAKKSRNDLLEMWGKELNCEEDVWHVFYCYVSRSANKCNQSVSII
PWNMEELRPETDLIVQQLAQLNKRGILTINSQPNVNGVPSDHPIHGWGAPNGYIYQKAYL
EFFTPKENINALKEALKAYPLVNYQIVDNSGKHDFTNSQSKTPIAVTWGVFPGKEIIQPT
VVDPISFKIWKDEAFGLWIQKWAQLYDEKSGSHALLHYIHDNYYLVNLVDNDFPKECCLW
QLLEDMFAIRHQNDINTSL
>J3NGV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gaeumannomyces tritici (strain R3-111a-1)|TrEMBL
MDKITDKIAALPADATYFSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
SQKSLELAEICQRELALTTCLHLTCTNMSRKLLDKALDDARALGIRNILALRGDPPRPGE
YGEPEDSEPADTAFTWAADLVRYIKQRHGDYFCIGVAAYPEGHADESHPTNQSLEHDLPY
LIEKTQAGADFIMTQLFFDIDAYDKFERTLREHPSGAFATIPIIPGLMPIQNYQMIKRTT
KLSHAGIPDSLMVRLDAVKKDDEQVKKVGVDIVSELVEKVKEVKSRTPGPQGFHFYTLNL
EKAVSFIVERTHLIPSSDPGEDEAVFADEAAIVADDASAAPSSLLGVPAIHVNGATPSHS
IQGVHSLSSRRQSSIGSDPRNRVIVSGRPASHPDYEATALEASVPAEPINSRANTLAISE
GEGVLGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSGTQAVELWGRPASVRDVSAL
FMRHLSGELRAIPWSEEEFNPETDTIRPPLLALNERGWWTVASQPAVNGLKSDNPTFGWG
PTHGFVFQKAFVELFIPSADWVVLRERLSQPGTSDSVCFYASNAAGDFVSSDSTGGLHGQ
AKAAGTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWAEWAKVYGKGSPSETLLES
LRADLWLVNIIHHDYVEPDALWDLLIKRE
>A0A239RWA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MSKKVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A2V4QNF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. pisi|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A0D6IVA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVAKVKAGANAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAELGDDKASIRAF
GVDVVTELCQNLLDNGAPGLHFYTLNHAEAPLAVWKELSV
>A0A143HQ63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbulbifer thermotolerans|TrEMBL
MTDSIRISFEFFPPKTPDGREKLYKTRAALQAFNPEFFSVTYGAGGTTRETTADIVTNLR
RDGISIAPHLSFGGDNEETILGLLNQYKNAGVNRIVALRGDMPSGMGAVAQLVYANELVA
FIRRHTGDHFHLEVAAYPEIHPEAESYDADIGYLKGKFDAGADSALTQYFYNPDAYFYFI
DQCQKAGIDKPIYPGIMPITNYTNLARFSRNCGAEIPRWLRQRMESYRDPEDVKKLGLEV
VTDLCETLLEGGAPGLHFYTMNQVEPSAAILTSLAISQQL
>A0A2C5TU13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morganella morganii|TrEMBL
MSFLHIDQHEALNQNLAELAGRVAVSFEFFPPGTPEMEKTLWQSIERLSVLKPKFVSVTY
GANSGERDRTHSVIKSIKEKTGLIAVPHLTCIDATRDELKTIARDYWDNGIRHIVALRGD
LPDSSSKPDMYAADLVGLLKSVADFDISVAAYPEVHPEARSAQSDLINLKKKIDAGADRA
ITQFFFDVSTYLRFRDRCAAAGIDVEIVPGILPVSNFKQLQRFAGMTNVRIPGWLGTMFE
GLDDDPESRKLVGASVAMEMVKLLSREGVKDFHFYTLNRAELTYAICHTLGVRPAACVA
>A0A2A4MVT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MENDQRTISFEFFPPKNEQAAERLAQTSAELAELEPEFFSVTFGAGGSTRSNTLECVSSI
NSNTGIDVAPHLSCIGSTEESIRELLEVYQSQGIKRIVALRGDMPSGMRDPGELNHANEL
VEFIRKTTGDHFHIEVAAYPEFHPQARSAQEDVANFKRKVEAGANSALTQYFFNSDAYFR
FLDDCSAAGINIPIVPGIMPITNYIQLARFSDACGAEIPRWIRRRLEGFGDDIESLRAFG
TDIMTELCATLLEGDAPGLHFYTMNQTRATLAIWQQLQG
>K5VC62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio harveyi|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDATRDELIDIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A2A5KSS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sophoriradicis|TrEMBL
MALKNEAQARNIGISFEFFPPKSEEMEGQLWETVSKLQDWDPDFVSVTYGAGGTTKAPTL
STVTRFLAQTPLATASHLTCVGATKDETHQVIDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGYDD
RPEERAKVAAEVAAEQIEDLVRRGIDEFHLYTMNRAPLVSAVLDNLGFSRRPAKSAGAAA
>W5YRI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter salarius|TrEMBL
METQKQFKRRFSFEFFPPKTDKGWEKLQGVRNTLAEVDPDFFSVTFGAGGSTRDRTVQTV
LDLHKRGVSTAPHLSCVGATRDSIAELLDVYRDNGINRIVALRGDMPSGMGAAGELRYAN
ELVSFIREYSGDTFNIEVAAYPEFHPQARTAEDDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCAKLLAAGAPGLHFYTLNQAEPSQSIWKNLGIGEREKIAF
>A0A661GAB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MLQHNAGNHLKTFKEAIGTRDFAVTAEFYLRPETDAESIREQAGVLADDVDGILLTDNQF
GHLHLCTVAAASLLIGIGIDPIVQLGCRNRNRISLLSDLMGAAAIGVTSLLLVRGARVPD
GFEPRPKAVLDVTATELIRIATTMKADERLKSLPDFFVGGMVTPHGAKPNWVPRKLQEKI
EAGAQFIQMHICMDIDLLRGYMKHLVAGKLIRRVSVMASVAVIESAEDAKWLRENRPNVM
IPNAIVERLEGAEDPQNEGIKICAEVLRELATIPGIAGANVIATRDLATIPAAIRMAGIS
S
>A0A0D6HW60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MSLIPRGTPFFPGNITDDCSLEVSVKDIAALTAAASRLPPGSTISIPYLPGQDDDARLAA
ARAVRGLGLEPMPHLSARRIASLADLEAFVSRAVAEAGVERCFVIAGDPSTPAGPFADSA
ALIETGVFERAGIKVVGVGAHPDGHPVMSAAQRWEVLERKCRGIGARGMSPLIVTQFGFD
ADIVLAWLEALRARGLEHPVRVGVPGPAGIAVLARYAALCGVGACASMWAKYGISLGKLF
GTAGPDVFVDRLAAGLTDAHGKVSLHFFPFGGIAQSVSWLERYRARSGQPGCATASLP
>A0A380TTV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADCTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A0J2GCL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella michiganensis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAKDYWDSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFRQAKKFADMTNVRIPTWMAKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A6B1GLU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGKLKQRIDAGEFIVTCELTPPKGIDLKPLLDKADSLKNHVHAFNLTESHAARMAMDPTA
VAHLLLDRGVEPIVQMTSRDKNRIAIQACMLGAAALGVENLVFMGGDPPKNGDHPDAKPV
FDLFASQLLDAVNALQSGTDYTGNKLNGTPSFCVGAVFNPGSTNPDVEIENLHRKIEAGA
SFLQTQAVYDVEEFTRFLDKCGDIKVPVLAGVIPIKSVKMAMYMNERVPGITVPDHLIQK
IADHQENKEKIVETSQQISADIVRDLRQAAGGLHMMAIGWEDKIPGIMELAGV
>A0A6I3E5I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRRPFSFDTPNGKPIFSLEFFPPKDEKGEANLWVELAELNSLQPEFVSVTYGAGGSTRER
TVRITSEITARTGLRTVAHLTCIGSSKNELSEILDQYWQAGIRDILALRGDPPTGPQSEW
IPTAGGFSHSDELVSLAAAANFNVGVAAFPDCHPASNGDHLKDISVLLEKERRGAQFATT
QFFFSTDKYYNLVNELKERGSNLPIFAGILPITQVKQLNRMAQLGGTPIPANIVQKFSRI
EDDPEKVKALGIEIAVNLCEELIAMGAPGLHFYTMNNAYATKEIVKRIGLR
>A0A6C1C1B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albus|TrEMBL
MAIGISAPRTERPPTVRDKLASGEKSFSFEFFAPKTPKGERTLWDALRRIEAVSPTFVSV
TYGAGGSSREGTVRNTERIANETTLTPVAHLTAVNHSRAELRNVIGQYANAGIRNVLALR
GDPPGDPLGEWVRHPEGIDYASELVELIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVN
KCRAGADYAITQMFFRAEDYLRLRDRVTAAGCDTPIIPEIMPVTNVKQIERFAQLSNATL
PDEMIERLRAVEDDPAAVRSVGIEYATQMCARLMAEGVPGLHFITLNHSTATLEIHQNLG
LRERA
>L0AKR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronobacterium gregoryi (strain ATCC 43098 / DSM 3393 / CCM 3738 / CIP 104747 / IAM 13177 / JCM 8860 / NBRC 102187 / NCIMB 2189 / SP2)|TrEMBL
MSSEIRTGEVADGIVTLLEEPRFELMPFDSMDDQLEHLPDGAEIAITTSPTLGLEATIDW
TERATDRGFEVVPHVAARYVRDEDHLAEIAGRLTDAGVTDVFVPGGDREEPIGEFTSAYD
LLSTLEDLAYEFEGIGITGYPEGHDFLDDEVLAEAMAKKEPYATYIVTQLCYDPQTILEW
IEEIRGRGVDLPVEVGIPGVMKYQRLLQISRKVGVGDSIRFLQKTSGVLGFLKELVGSRG
TYVPDELVAGLAPYATDSYYDVCGVHVYAFNQVPDLESWRSETLTQYG
>A0A099UCD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter typhlonius|TrEMBL
MYDIESLIEQLHSTEPFLSVEIAPSISGRLDENLLEDLKTLKLAHAFVCTDSPLARFKPS
SILSSLKFQNALQKPVICTISMRDRNSIALCGDILSVNELGLRTFLTLTGDSIKNGDCLQ
SKGVFEDNSLKLGHIIDELNCGRALNGKSLKENIKRIYNFQVINAYANNPLSLKNKMRKK
LSSCEIHALFTQPVYSLNAAEFLLQSLEEIKSECNIKSALVLGFFPVLSYKTALFLRDKL
PGVYIPNEWVQKLEKAHNKGKDEEKKVGLEISHSLFMELKSVHNKFHFMSANKPSLVKEF
A
>A0A099TXC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter muridarum|TrEMBL
MENHHLVEDFINKIRNKKCLTYEICPDKSPSIMPIISKIKLAKLHEDIIDGFVCTDSPLA
KLKMHSGMASIKIQQELQKPVICTISMRDRNSLALSAELLGLNEFDIRIFLALSGDPLKL
GDQPQAKAVFEGNSHRILELIEKLNSGLDLVNNALKSYPKQIYGFSVLNSYSKKVNILKN
KMESKICSNALALFTQPIYDIEVSKILHEWLEELNARHNKQCVIMQGFFPITSFRRALFL
YEKLPGVFIPELWLETMQKASLRGVDYEKQKGLEMSSELFSRLYEYSPKIHFMNHNAPNS
AKRILEHVR
>A0A1Y3LVR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter agilis|TrEMBL
MTVRPGLPLHVEVIPGEALLERLLTHLPAPVTVSVTCLPHHGPQEAVQTAVGLADAGYTA
IPHLAARSVTDRRALAGYVHQCLDAGITEVFVIGGDRPEAAGPYAWSGALMQDIADLSGG
GLRMGIAVYPEGHPATDDGELVATLRSRQDLASWSVTQLCFDPETLRAFPGRLRADGIEL
PVWAGIPGPVRVSRLLRLTRRIGVGQSLGFLRRSAGGSNSGSVMRQLVTTASYDPAPLVR
AVDGAGYAGLHVYSFNDLAELAGSELAAPITGGR
>A0A0A2Z7T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallibacterium anatis|TrEMBL
MSYAKEIDVLNRSIADLNGDINVSFEFFPPKNEKMETLLWDSIQRLKSLQPKFVSVTYGA
NSGERERTHSVVKAIKQQTGIEAAPHLTGIDASPEQLKAIAKDYWDSGIRNIVALRGDEP
PGYDKKPFYAKDLVKLLKEVADFDISVAAYPEVHPEAKSAQADLIFLKQKVEAGASRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFVQLQKMAKVTNVKIPSWMFKLYDGL
EKDQTTRNLIGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGVRPSLAA
>A0A5H8UJF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Kedougou|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A348V5P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium|TrEMBL
MKISDFFNQEGKTAFSFELLPPLKGNSIQQIFNTIDRLKEFDPKYINITTHHSENEYKED
EQGVYRKVNVRKRPGSVAIAAAIQNRYGIKAIPHIISQGFSKEETEYALIDLSFLGVTDL
LLLRGDTKKLDGEQRKMDSHLHATGLQEQVNNFNKGIAYDGSTFTPPDTPFAYGMACYPE
KHEESPNMESELLYTKMKVDEGADYLVTQMFFDNSKYFAFVDRCRAAGITVPIIPGIKPI
HLKNQLTVLPKVFRSDIPADLEKELRRCKDDAEAREVGVAWCVAQCRELMQHNVPGIHFY
ALMATESVHKVASEIY
>A0A352J0W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium|TrEMBL
MKISDLIHQTSKPVFSFELLPPLKGNSIKQVFNTIDRLKEFGPKYINITTHHSENTYKED
ENGIIRKVNVRKRPGSVAIAAAIQNKYGIRAVPHIISQGFSKEETEYALIDLSFLGVTDL
LLLRGDTKKLDADQRKMDCHSYATGLQEQVNNFNNGIALDGSTFPAPETPFTYGMACYPE
KHEESPNMESEIYYTKMKAQNGADYLVTQMFFDNQKYFDFVDRCRAEGITIPIVPGIKPI
HLKNQLNVLPKIFRTEIPEDLEHELRKCKTDADAVEVGVEWCLLQSRELVQRGVPGIHFY
ALGATESIYRVAREVY
>A0A2S8DVE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella boydii|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A540PKI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces ipomoeae|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSV
TYGAGGSTRAGTVRATEQIAADTTLTPVAHLTAVSQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSPDWDSDVARFVD
KCRAGADYAITQMFFHPESYLRLRDAVAAAGCETPVIPEVMPVTSVKMLERLPKLSNAAI
PDDLKERIVTAKDNPAAVRSIGIEFATEFCRRLLDEGVPGLHFITLNNSTATLEIYENLG
LHDSPRA
>A0A6B1EFT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MGSRLRFRTLVSESLGARLHRLELIAGLTFEVIPLKSLEGAIESLPEGSTVSVTASPVKG
QEATCEITERLMALGHMAIPHVSARLVPDRARVVELAGWLRSAGVSTMFLVGGDVESPGA
YSDAASFLRDLLECDHGLTTIGVTAYPHGHPLIDDSVLHEALHTKQALLAEAGLQGYCST
QMCFDPGRIEDWLRAERASGLTLPVHLGISGVVERTKLLTMGARLGVGPSLRYLRKNRAA
IMKLMTSPNYSPDHLLTALSPSLEELDVTGLHVFTFNQVGATASWQASHRRH
>A0A7Y1TFX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MTSETVARPSVTFEFFPPNTAAMEATLWKSLERLGELQPAFVSVTYGADGSTRERTHAAV
ERIIRDTTLTPAPHLTCVGASRGEIDDIAREYWDMGVRHLVALRGDAPKGCDAYVPHAEG
YAYASDLVEGLRNIADFDISVAAYPEVHPDAPSADFDLDNLKRKLDAGATQAITQFFFDV
DVYLRFRDRCSAAGIDSPIIPGILPITRFPQLERFAKMCGASVPDWLRDRFEGLEDDDET
RQMIAASVAIEQIHALEKEGIEEFHFYTLNRSELTYAICYAIGVRPDQAAA
>A0A3D1G130|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTDLKDAIAAAGQHWSIEVTPPGATKIDSFAEILAPDTTVNVTFLPGTDPMDTVDVAVRL
RDDGMNPVPHIAARSVQSRDQLGSIVKEMASRANIDEVLVIGGGVDNPVGDFASSMEILE
TGVLQENGISRIGVSGHPEGSPDINDDQLAEALEWKNDFARREGLELYIETQFCFEADPV
IAWENRIRARGNDLPIRIGIPGPATIKTLLRFAQISGIGPSMRMITKQARNVTRLLTVQS
PHTLITGLAEAMANDPESRLSHFHYYPFGGFARTEKWATAVAAGDFDLLPKGGFSVKEN
>A0A8E4GDC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. juglandis|TrEMBL
MDPDTPSLASTITEAYSLEVSAKHIAGLAAAAPRIMRGATIAIPYLPNQDDDARLAAARM
VRTLGFQPMPHLSARRIASREQLHAFVSRAVDDAGVERCLVIAGDPPAPLGPFPDSLSLL
DTGVFERSGIRTIAVAGHPEGHPSMPAADRWEVLQRKCRSIAERGMAPLIVTQFAFDADI
VLRWLQALRAHGIAYPVRVGVPGPAGVAVLARYAASCGVSACASMLSKYGISLGKLLGTA
GPDRFVERLATGLTDAHGEVRMHFYPFGGIAQTVAWVEQYRSRSARV
>A0A6A3RMM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora fragariae|TrEMBL
MSTPTSPALASKGESEQQLHTQAAISGEELYLQELTEALVVPAVQITTRSLENSSSPVPS
TSSEDECSPDPESPVEHAEEELERGEIHDNRDPSNDTELVDDGEPTTDVVVKFSGVHKAE
ATEAQADETPAPPLQPPVVEISTSRTSQLPGEGQRCNRHMDPPQTLDTCDSRLLPNDSLA
TSVSAFIKWEEAAALEAFPLAVVPSNHPHTREKGSKMPRVSSIHVTKQKERHEEADELAA
TKFVLDDSTVWTGLSTEDTRAAGESEGDQERLLQRLHLVQGLLTFVRMLRRSRGLQAEEE
DDEAKTSAQWTPEWASLKRALGLQRLKAKQDAGADFIITQFFFDVDNMIHWIADCKDAGI
TILPGYLSIQNYSSLCKFTSWCKTRVPESVLAALDTIKNDDAAVRRYGTQLAAETCQRLL
AAGVNSLHFYTMNLPRP
>A0A222GJS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium meliloti|TrEMBL
MNGRTPYPVDCDGLRFSFEYFPPKNDEMETQLFQTVTALSVFAPAFVTVTYGAGGSTKAR
SLTTVKRMIGEMEIANTAAHLTCVGAPKAEVDAVIDEFLACGVRHFVALRGDPQGGIGSV
YEPFPGGYENAAALVKALRARGDFEISVSAYPEKHPESPDVAADIDMLKRKVDNGATRAL
TQFFFDNDDFERYLERVRRAGIAIPIVPGILPINNLTQVQKFAGLCGARVPESIVSRLGP
IDDQPEERFREAAHIAAEQVADLVRRGVSDFHLYTMNRPQLITAVCELMGYDPEIAPAQP
ADTERSVRAVARA
>A0A1X1K9E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALQNMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLTIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDIPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A5Z1CCW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEIEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A011TBR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquamicrobium defluvii|TrEMBL
MSQYRFSRRPDIGEGIRVSFEFFPPKSDEMETRLWDTVTRLQPLQPHFVSVTYGAGGSTR
ERTARTVARILHQTDLSPAAHLTCIDASRDEVDAVIRQFADLGVTRFVALRGDPATGVGT
GYQPHPDGYANGAEMVAALRRQGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDIYERYVERVRRAGIYIPIVPGILPVHNIVQVANFSARAGAHVPAWLRERFA
GLENDPQTHALVAAAIAAEQVHDLIERGVGDFHFYTMNRADLAYAVCHMIGIRPGSNGGE
KSAAA
>A3AP03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryza sativa subsp. japonica|TrEMBL
MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLK
QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNL
GLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLD
QLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWK
DEAFEIWSKGWACLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAFKEI
>A0A218XJE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Punica granatum|TrEMBL
MKVIDKIREAAVCADGEGAGSGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPNFCDIT
WGAGGSTADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALTTIKSNGIQNVLALRG
DPPHGQDKFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDVIGPDGMATLEAY
QNDLAYLKRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGISCPIVPGIMPINNYKGFLR
MTGFCKTKIPPEIMAALEPIKDNEEAVRNYGIHLGTEMCKKILANGIRTLHLYTLNMEKS
ALAILMNLGLIEETKVSRSLPWRRPTNVFRVKEDVRPIFWANRPKSYITRTMGWEHYPRG
RWSDSQSPSYGALTDYQFMRPRARDKKLKEEWTVPLSGIEDVCEQFKKLCLGKLRSSPWS
ELDGLQPETRIINEHLGKINLKGFLTINSQPAVNAERSDSPSVGWGGPGGHVYQKAYLEF
FCSPAKLNALVEKCKEFPYLTYMAVNKDGSSWVSNVGKSDVNAVTWGVFPAKEIIQPTVV
DPASFAVWKDEAFEIWSRGWACRYPEGDASRKLLEEIQGSYFLVSLVDNDYINGDLFAVF
SDI
>A0A078GZ08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica napus|TrEMBL
MKVIDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGSTA
DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK
FVQVEGGFGCALDLVNHIRSKYGDYFGIAVAGYPEAHPDVIGENGLASKEAYQSDLEYLK
KKVDAGADLIVTQLFFDTDMLLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCKTK
IPAEVMAALEPIQDNEEAVKAYGIHLGTEMCKKILAHGIKSLHLYTLNMEKSALSILMNL
GMIEESKISRSLPWRRPANVFRIKEDVRPIFWANRPKSYISRTKAWENFPQGRWGDSRSA
SYGALTDHQFSRPRARDKKLQQEWVVPLKSVEDIHEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLVKVNSKGFLTINSQPSVNAERSDSSTVGWGGPGGYVYQKAYLEFFCSKDKLD
ALVEICKALPSITYIAMNKGETWVSNTSQSDVNAVTWGVFPAKEIIQPTIVDPSSFNVWK
DEAFETWSRNWANLYPEEADPSRNLLEDVKNSYYLVSLVENDYINGNIFKVFSDL
>A0A3M6XCE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMSYDAEVFIEWAKKVRAAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAELFVKYMSGKVETLPWSEQPISPESNVL
TNDLVNLNSRGLLTINSQPAVDGMKSSHPVYGWGPNNGYVYQKAYLEVLIPPSLIAEIIR
RMDANPDITYYAVNNSGELKTNAPQDGGPNAVTWGVFPGKEIVQPTIVETISFLAWRDEF
YHLGSEWAKCYDEGSRSKNLIKEITESWYLVNIVDNDFRNMRGIFPLFDGLKVDGVEPTA
AAVNGVAHVNGDVNGDAEKKERALKPEVNGVPDKNNAVNHADGAALNGQQVKN
>A0A535NS40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAASPFLERLRRGPLLGDGAMGTQLHARGVSFERSFDELNLTQPKIVEEIHRAYISAGAE
LIETNTFGANRIKLARHGLEDRVRDINLRAVKLAREAREIAGDPVFLAGSVGPIGQQLEP
IGRISIAQATAAFEEQIAALLEGGADLLVLETFTNLPELLAAVAAAKHTTDLPIVAQMTF
AEDGLTLSAEEPSQVVQALEQAGVDVIGVNCGVGPQVALQVLEAMRQQTRLPLSGQPNAG
LPARVEGRFFYFATPEYFATFARQAAELGVAYIGGCCGTTPAHIAAMRAALRPVATGTPI
QRPAPSTAIAIDLNPAEQLPPTPFAQRLAAGTFVVSVEIDPPRGLNPAKCVAGAQLIKDA
GADAINIGDSPMARVRMSALSLALMIEQQVGIDILIHFTSRDKNLMALQAELIGAHALGI
RNIIALTGDPPRIGDYPSATGVWDVDSIGLIKILQRLNEGYDWLGTSIGKPANFTIACAV
NPSADDLGHEIDRFRQKIEAGAHVAMSQPLYDRQTLERFFEKTGPLPIPFLLGVLPLQSS
RHAEFMHNEVPGIVVPQQLRDRMRRAGENGIAEGLQQSRELLAETRDLVQGVYLMPSFGR
YEVVAELVRWLRQDRVTTALR
>A0A5F0S0Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus mirabilis|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTQEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHAIIKDIKERTGLEAAPHLTCIDACREELQHIAQDYWQSGIRHIVALRGD
LPDNSQKPDMYAVDLVHLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKKKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMFD
GLDNDPETRALVGASIAIDMVKILSREGVKDFHFYTLNRSELAYAICHTLGVRPQLAKV
>A0A0R9NFV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella newport|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRNSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A420FMB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium siyangense|TrEMBL
MKIIDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTDGGHAFATDLLEQVTDMNKGKYLHEDIITSEKTDFCIGVAGY
PEKHFESPNFNTDFKYLKQKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVSACKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLA
>A0A496ZG83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTINFSDNRFNILIEVVPPAGPDGGPLMHLLKSISGLSFDAFSVATNPVAKPRMSAMAT
CALAQQETDKPAILHCTTRDHNRIGLQGILWGAQALGIKTVLVATGDMVALQNRNITTRV
RDMDVFGLVGMARQSGLQTGVVIDPHPEANGFETAIRRLTQKIDAGAQFAVTQPIYDAET
ADTMAQATQSMGIPVIMGILPLRTARHAGFLHQKVAGIAVPKRLRKQIQQADDTIKTGNQ
NAREMLAAARERFAGACIMPPFDHYEVLEDILDFDTI
>A0A2X2J6Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium multivorum|TrEMBL
MKIIDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTDGGHAFATDLLEQVTDMNKGKYLHEDIITSEKTDFCIGVAGY
PEKHFESPNFNTDFKYLKQKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVAACKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLA
>A0A3L7XYM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSINLQEKLNRGTLLADGALGSELYARGIKNGSCLDALNLTNPAAVLGVHASYLQAGAD
LIETNTFGANSFRLASHGHAEQVVVINQTGVALARQAAAASGRAVAVAGSVGPLGVRLVP
FGRVKPEAAYAAFCEQISALLAAGVDALVLETFSDLMELSEAVRAARACSTAQQPVLLVA
SMTFTRDDRTQLGDSPAHVARTLAGLGVDVVGANCSIGPAQLLRVLQAMHAAAPQLALSV
MPNAGMPEVSGGRVLYPAGPDYFAQLTPDWLATGARIVGGCCGTTPAHIAALRQALDTPR
AAAVHSAPARHSSPAEALPATDEPTKLATKLQSQQFVITVEMSPPKGYTPHKVLAGAHML
AESGADVINVADSPLARMRMSPWAVCHLIQQQVGIETVLHFPTRGRNLLRVQGDLLAAHA
LGVRNVFVVMGDPATIGDFPQAFDNFDVAPTALLQLVKQRFNAGMDQAGQDIGQPTSFVA
ACALSLSAPDPAREIKLLRKKLECGADFALTQPVFDAQVARNFFARYAAEHGALQLPVLV
GVLPLYSERHASFLHNEVPGIHIPEQIQHRIARAADAPAEGVRIALELIAELRATTPIRG
AYLQPPFRRYELAAEIIEHTRAQD
>A0A3M5YE62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. phaseolicola|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A090KE95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moritella viscosa|TrEMBL
MSFHNAQNIEVLNQSVSELGRDINVSFEFFPPNSEAMTSTLWESINRLKALDPKFVSVTY
GANSGTRDRTHDIIKQIKHETGLVAAPHLTCIDANRQELKQIAKDYWDNGIRNIVALRGD
LPTGLNQPDMYAADLVALLKEVNDFDISVAAYPEVHPEAKNAQADLLALKDKIDAGADRA
ISQFFFDTESFLRFRDRCAAVGINKEIVPGILPVSNYKTLCKFSKLTNVKVPNWMHSQFE
GLDNDQATRNLVGASIAIDQVKVLSREGVKDFHFYTLNRADLTYAICHTLGVRPR
>A0A0A6S566|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A359KQX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MANPFIERLHAGPILCDGAMGTQIHAGGVSFDTCFDELNLSSRDAIVQIHRDYIAAGADM
IETNTFGANAFRLGEHRLDDRVRDINYRGARLAIEAREVSGVPVLIGGSVGPTGMAQVPF
GLYRPEQVRAAFREQIGALLEGGVDLLVIETMGSLAEMTEAVLAARDVSDLPIIASMTYS
DDGRTLGGSTPAEVLQYLHELAVDVVGANCSVGPRRVLDVLGELRSLDREVRLSGMPNAG
WPMQIDDRFVYPSSPDYFAAFAVESLDLGLAVLGGCCGTTPEHTKAMREAIDQRLRGEGI
QTLRRPTPARSIELLPPEAPTEFARKIGKQFLVSVELDPPRGLNPQKMIDGARMLKAAGV
DAVNVADSPMARIRMSALALCFLIQTEIGVETILHFTTRDRNLMGLQSDLLGAHALGVRN
ILALTGDPPSLGDYPNATAVYDLDSVGLARVLQSMNAGTDAAGASIGKQASFTVLVAADP
TRDDLAHETDRVARKVAAGADMIMTQPVYELETWRAFVRLYEERHGALATPVMLGVMPLQ
SHRHTEFLYNEVPGIRPTEAIRERMRLAGSDGRREGVRISQELILEARDEVHGVYIMPSF
HRYEVASEVLEAIGDRRLTAQLPSNT
>A0A3V9PWI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Bredeney|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3V4SQM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Altona|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>Q5TWY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles gambiae|TrEMBL
MATTNTVTNEEQSNEHSLHTKLNRIFNSSTTSGPVPVHYSIEIAAKDDFDIDQLKRLTPQ
PVFCALPWISDDNLRYADDFLRSPTLQLTARLRENQYTVLNNVSCYNITEQQVDQLLRAT
GIRNLFVIRGDTVSPGQQFQNSAGLVQHLRKWQEQQPNHRQFTIAVGGYPYGHYQSSSQT
VELHYLRAKISQGADFLLTQTLYDAPSFLRYRDRCREAGITIPIIPGIYVPHSYRHLQAL
LNLTRIELGPTVRDAFEAHANDAPDQFQAFMVEYFVGVVRELLQMNATTSSDPIKLVHFF
TFNKFHLLQEVLGKLDEFFK
>A0A7U9RKB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MVCKMKVMDIFEAKKKEGKPVLSFEIFPPKKEEALKNIDATLEKLCDLHPDFISVTFGAG
GSAVDNQTVEIAKKIKNTYGVEPIVHLTCLHYEKEEIKAILNQLQESGIENVLALRGDEN
PNVPMKQDFKYASELVAYIKGQGDFHISGACYPETHLEAPDAITDIHNLKKKVDAGAAHL
VSQLFFDNEMFYRFYEKTRIAGIDVPVEAGIMPVTNKAQIERMVNICGASLPKKFEKILH
KYENNKEALFDAGLAYAINQIVDLIANDVDGIHIFTMNNPKVAGRICDGIRNLI
>A0A357YFP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MSRLEQAFAAGTFVVTAEIAPPKGIAVAAALAKAKALPEGVTAVNVTDNQGANMRLSPLA
LSALLVREGIEPVLQLTCRDRNRLALQSDLLGAAALGVENLLLLSGDHARFGDHPEARSV
FDLDSVQLLQAVSGLMAGRDMAGKALNGVPSFFVGAAVAPAAEPFDLMLSKVNKKAAAGT
RFFQSQAVFVPAELERFMLAVRPLQVPVMLGVLLLRSANMARFLNANIPGVQVPAVLVDR
LDAAVDPLAEGVAIAREMVQAARDLCQGVHLMTLGHEDKISAILAR
>A0A087EEA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium tsurumiense|TrEMBL
MGVPQFSLEVFPPKRNGPVGTIYDTLDGLEGVRPDFISVTYGTGRSADRTATARISHTVR
SEYDIPVVAHLTAQYLDEQQADEALDMFQQAGVKAVLALRGDRVEGRDPAGVFCHASDLV
AYIRKTCPDMDVFGACYPECHPDAANLDEDIAHLKTKVDAGASHLISQLFFDNEDFLRFV
DKARAAGINVPIEAGIMPVTNAAQVRRMVSMCGARVPAGITAILDRWGDDREAIKQAGIL
YASQQIADLVSQGADGVHVYTMNHPATTRKIWNNVSSLFANR
>A0A3Q7MVA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callorhinus ursinus|TrEMBL
MVNEPRGDGGPPPRSEGSSSGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSQEQITGYLHKAKRLGLKNILALRGGVEAALYSLGSCFLEGLFCPYPV
GDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAG
ADFIITQLFFEADTFFHFVKACSEIGVTCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIK
DVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIE
DPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELK
DYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYLSGEPNQHGHKVTCLPWNDEPLA
AETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRET
VGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFM
FWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFE
LLNRPTPEQGEEAL
>A0A4P6M0X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia producta|TrEMBL
MKLSEAMKNKMLLSFELFPPKTDKGMENLPGTIEHLCKYQPEYISCTYGAGGTNVGKNMD
VCKMIKDAGTIPVTHFTCIGNTAEGIKEQLQNYLDNGVDHMLALRGDLPFGWTGTGGDFA
YATDLVAYVRKEFGDKIEIAVAGSPEGHIACRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKRWMDAIRTAGITMPIDVGIMPILDQAATINMALSRNGCVMPRKLCEIISKNWIFPN
PFDKDPFDAAVDEKKAAFKEAGIEYTIRQIDEYRALGVNGIHLYALNKWKDVSEIIDRCG
LRTLV
>A0A1B1KIE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus opacus|TrEMBL
MPNFQARPVDVNECVRTLVADANIEVIPLKGADEKIHSAPTGTTVTITCSPKFGLERTVQ
HVASAISQGYQVVPHLAARMVESEQMLRDFIRRIVDLGVTDLYVVGGDADQPLGKFYDAE
SILLALREFDHGLTRLGVGCYPEGHPKIENEALIESLVRKQEYADYMVSQLCFDAGALVT
WLRQVRSRGIVLPVRVGLAAPLKTAKLAELSIKIGVGRSLRFLTKQHGLLGNLVLGRDYA
PEQLLIDIGPDLLSSDLDVEGIHLFSFNQIEATVDWQRRIASNY
>A0A5C5H8V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Give|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4S2AH43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKRLSEMMKERQLLSFELFPPKTDKGMENLPGTIGKLCEFEPEYISCTYGAGGTNVGKNL
DVCQMIKEAGTTPVTHFTCIGNTREGIKEQLENYLKNGVDHMLALRGDLPFGWTGTGGDF
KYATDLVAFVRKEFGDKFEIAVAGSPEGHISCRSLDADVAVLKQKQDNGADYIMTQLCWD
MEQFKRWQDKLDRAGITMPVDVGIMPILDQAATINMALSRNACVMPRALCELISKYWIFP
NPFDKEPFDAAVDQKKADFKKAGIEYTIKQIDEYRALGINGIHLYALNKWKDVTDIINES
GIKTMV
>Q0BJC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia ambifaria (strain ATCC BAA-244 / AMMD)|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRADLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFTQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTASATRTICERLAM
>A0A381D3H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni subsp. doylei|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IQKQGEFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKPKAAIKIYEAVKHLLKEELRA
>A0A6M2W1J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. punicae|TrEMBL
MIPTDMPSGASTITDTYSLEVSVKDIGALTNAAPRILPGSDMFIPYLPGQTEAARLAAAQ
RVRRLGFEPVPHLSARRIGSLEELQAVIARLVGETDVTRCLVIAGDPSTPKGPFADSVSL
IETGVFERSGIRTIGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
IVMTWLEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLVSRLTEAHGDVRLHLFPFGGIAQSVEWVAHYRSCEASQDRVSPVAAD
>A0A716M1Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Typhi str. CT18|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVVDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7Z7LV57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia anophelis|TrEMBL
MKVTEHIAQSKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGEKYFEPTKGGNRYASELVTQINDLGKGKFLHGEISGNDTNNSFCIGVAG
YPEKHLEAPSMQYDLKMLKQKVELGADYVVTQMFLDNQKYFEFVKLAREAGIDVPIIPGI
KPFAVKKHLQLLPQVFKIDIPEDLVNAVSQCKNNEAVKQVGIEWCVQQCKELLDFGVPAL
HFYTMGKSDNIQKIVSEFF
>A0A501Y4G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. LC6|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETNLVAAPHLTLVDASDEELLDLAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPSWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPKAV
>A0A6J6VM00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTKIRDLLAAGPTISFEFFPPKTDTAMRALDAALEELSLVEPSFVSVTYGAGGSTKDRTR
SIVLGINETRPFPAMPHLTCMSHTKAEVIDLLDDYADHGIENVLALAGDPPTDADTPLGE
FRYALELVELVRDKGDFSVGVAAFPELHPRSQGRSADDRQHLAAKLEVADFAITQFFADA
DDYGRLLDDLDALGVTKPVLPGIMAPNNPAGYRRMAAMNGTRVPEALLARIDAADAADAI
SLAVEATTQQCLRLRELGAPGLHFYTLNRSELTRRVHANLVG
>R1CI82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emiliania huxleyi|TrEMBL
MSTMLGTLYNETSSGQVSAHEIARPALLAAIERLAALQQRGEPFVVADLGVAAGANAVSV
ARLVISEFMGRRPGEAISYAFEDLPLNDWTVLAQTVSAAELPCFTSFVPRSFYEPLFPPA
SLSLSLSFITLHWLSEAPRLSADAVLAMERHTAADVAAEWRDQAHVDLVSFLRLRATELK
DGGEGVYLMVGGGAALPVHEWARPPSGGPSIFSVALSRAVAAGDIDEAAAMAASVAYHLR
TDDEVRRAAGEVGASLELLDVTSAEVRVAEGRSAEEHADLAWAIHSNSILSSSGIGDEAG
ERVRLHLRDVVATEFGDSGATISYVSLAVRRRPREANAASEEGAVAPASEARGWDPMWLA
RALADPARPTFLFGSTPPRDGTTAAEAAQICAKFVARSRAHASDGFIVYDIQDESSRNAE
SRPFPFRRTIDPSEYAQHFPPASGKSTACSEADEAAFASWLDGAQRRNHHTLNLVGPSSS
GDTPRISMERAAALVNERPGMAFGCVTIAERHLTKGTEHLNLLRKAGYGAKWFISQAVYD
AEATIKLLHDYAGECRRRGCRPVKILLTFAPVGRPKTLQFVKWLGVHVPSAVEERILAKA
NATESKTKEAAVLESIDALQRILQMAGGCGVPLGLSVESLSGFREEIDGCFELFRRLQAT
MLDSVCSPWAVRWYRVPVHSMARSHSEEQLAADAGPEMAEEEQAGSRAAGSI
>A0A265DTL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas boliviensis LC1|TrEMBL
MSSQEHPLGISFEFFPPNTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTRQVVR
EVSESGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIREETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSDAIAAF
GTDVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKIVDNLTD
>Q8YI86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)|TrEMBL
MEQRLWETVTRLAPLQPDFVSVTYGAGGSTRERTVRTVARILKETDIKPAAHLTCVDATR
EDVDRVAREFAALGVNRFVALRGDPANGIGEKYVPTPGGYQNGAELVGGLRNIADFDISV
SAYPEKHPESPDFATDIDMLKRKVDNGATRAITQFFFENDLYERYVERVRRAGIYIPIVP
GVLPVHNFKQVRNFCARSATHIPAWLAERFDGLDNDPQTHQLVAAAIAAEQVMDLIERGV
QDFHFYTMNRADLPFAICHMIGIRPKTQAALEVA
>A0A6P8WR77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila albomicans|TrEMBL
MCFNLNRIRPASALLRSIKALSRSQYNLQYQLRFKYEYLEPKRTTKSGGDSAMDGEPKLP
WSPFKPCFTFTDAQKELCLKDVNIADIVREKTERKEFFYGIETKPLDGDETACLDFHMFL
PQMPEFISVVWTKRFSDAIEEATMARIPNIQMMPCLTPYIPAMIHMTVYKLTQQHLNDFL
DLNLNNVLMIRGDHVEEGQEYNYAYEAVKYLRCVRSDMAIAVAGYPEGYTNLQVGPRDKE
LDMEYMKLKMDSGADFIVTQLCYSGDTIVEFLQDARNAGITAPIMLGILIPESFARYERM
AGFSKVFLTPEQLAEVEPIKDDDDAVMNYFIQLSVRNIQQTLAANLGVYGVHFYTLNRFR
PILDIIAELRKLGILSC
>A0A6J7P8P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARIADLLARGRTFSFEFFPPKTDYAQLTLGRTIAELESLSPGFVSVTYGAGGGTRARTH
AVVEWVRKETHITPMAHLTCTAHSRAEISEILANYTDAGVENILALGGDPPAAGAEPGPS
DYSYALDLVEHIASAGGFSIGVAAHPEMHPRSADRASDRRYLAEKLKRADFAITQFFFEA
DHYFRMVDELASLGVDKPIVPGIMPVTNKNQVKRMAELSGSVFPAWLAERIGDSGDEAEV
ARIGVEVATELCATLLEGGAPGLHFFTMNRSNATREIYGRLGLPTF
>A0A1D3P618|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTLVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGILISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A746G2F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVCIPSWISLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2S9VRD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus pentosus|TrEMBL
MNLKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHQSYIQAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVRIAVTAREHADHPVYILGTIGGLAGDTDAAVQR
ATQAEIAANVTEQLTALLATEQLDGILLETYYDLSELLAALKIVKAHTDLPVITNVSMLA
AGVLRNGTSFTDAIVQLHAAGADVIGTNCRLGPYYLAQSFENLAIPADVKLAVYPNSGLP
GTDQDGAIVYDGEPSYFEEYAERFRQLGLSIIGGCCGTTPLHTAATVRGLSSRSLVPHNA
PTHVAQAPTLVTTKSQHRFLHKVVTEKTVLVELDPPRDFDTRKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTAIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAV
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TDVSTKSISRKLSYGCDYIITQPVYDLANVDALADALAANQIDVPVFVGVMPLVSRRNAE
FLHHEVHGIRLPKSVLERMQQAELDGNERAVGITIAKELIDGICARFNGVHIVTPFNRFK
TVLELVNYVQQKNLTKVQ
>A0A3S3DJH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MTIRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A0G9C022|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas perforans|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGAAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCQRLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A163MHM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycosphaerella rabiei|TrEMBL
MEKITDKIHALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMDRALVDEALEQAKVLGIRNILALRGDAPRSEE
YRDEDKTPEQDSNRDFTWAIDLVRYIRQQYGDYFCLGVAAYPEGHSDESHPEHQNPSYDI
PHLVEKTRAGADFIMTQLFYDVHKYDKFETLLREHESGAFKTIPIIPGLMPIQSYSILRR
TTKLSHANLPADLLARLDAVKADDELVKRVGVKILAEMVEHIRSRPDVVRRGFHFYTLNL
EKAVSHILEDTNLIGQIPTEDDGDVIETTPAINLEPPSGIPSNRQRRRLSSINSSPHNRV
IRERLSASRSNQSFETSDTEAGQPRGPVNTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSNTSALKLWGHPVTQNDISALFKRHVEGTLEALPWSEQTLSE
ETSTIAPQLLALNAKGWWTVASQPAVNGVRSTDPVFGWGPKNGYVFQKPFVEFFIPSAAF
SELKPRLDAHEQITYFAGNAAGDFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFKSWR
DEAFSIWKEWQRIYPTKSATGKLLRETRNDVWLVNVIWGDFVEGDGLWEFLSA
>A0A163MHM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Didymella rabiei|TrEMBL
MEKITDKIHALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMDRALVDEALEQAKVLGIRNILALRGDAPRSEE
YRDEDKTPEQDSNRDFTWAIDLVRYIRQQYGDYFCLGVAAYPEGHSDESHPEHQNPSYDI
PHLVEKTRAGADFIMTQLFYDVHKYDKFETLLREHESGAFKTIPIIPGLMPIQSYSILRR
TTKLSHANLPADLLARLDAVKADDELVKRVGVKILAEMVEHIRSRPDVVRRGFHFYTLNL
EKAVSHILEDTNLIGQIPTEDDGDVIETTPAINLEPPSGIPSNRQRRRLSSINSSPHNRV
IRERLSASRSNQSFETSDTEAGQPRGPVNTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSNTSALKLWGHPVTQNDISALFKRHVEGTLEALPWSEQTLSE
ETSTIAPQLLALNAKGWWTVASQPAVNGVRSTDPVFGWGPKNGYVFQKPFVEFFIPSAAF
SELKPRLDAHEQITYFAGNAAGDFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFKSWR
DEAFSIWKEWQRIYPTKSATGKLLRETRNDVWLVNVIWGDFVEGDGLWEFLSA
>A0A441DHN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDQIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHLLHDEITETQVDMVK
TAH
>A0A3S3LG74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVNAARHEVDEVIQEFAEMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRAGALVPAWLAERFD
GLQKDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
GSAAA
>A0A3S3IYC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A3V5VYW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Ohio|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A378GGY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyvera ascorbata|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLRRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSAMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A442G6F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFVDFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>A0A442FED2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAQRLDHILHDEITETQVDMVK
TAH
>A0A6J5KCT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia phenoliruptrix|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLALLKPKFVSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHLSCIGSSKESLRAILNQYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
EARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCARLIDAKVPGLHFYTLNGAAATRAICERLKG
>A0A8B5S208|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bereziniae|TrEMBL
MSKRIPISFEFFPTKTDAGAEKLKIVHQELQQFNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGDHFKIEVAAYPEMHPQAESYDADIQHFIEKVNAGANAAITQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHTEPNRQLILDLGLA
>A0A8I1DG00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bereziniae|TrEMBL
MSKLSQYFAQNQFCCLVEYLPTKNQVLPARESLAGFPACMTLSDRVRSDEDIAPLIAAQA
YPDHIEKVLHYAGKGRDIDDFKLFLKQADSVGLRDILLLTGDKLKQHHDGQGQHARTRYL
ESVNAVMAAHQYGGFHIGVAFNPFKYTPAEQQAQYLKLHKKLNAGADYIITQLGFDLSAL
KQLQTFLAQEKYIQKTLACVMPLTLARAQFMVKHKVAGIVITPHMLEVLAQDQVNQCPEN
VYKRCALQILICQHLGYAGVHLSACHKADEQMLLEQYIEQYRDLNLSQCEILWNQLWQLA
EGEQLRPIVAAKRIKSALNNKVKYQFLDLIHRAMFQSSFMKGVGTFIFNASFWNRKTAAK
VLLQTEYLSKHYLLGCESCGQCRLAETLYICPETCPKGLANGPCGGTDLDRCEFGDRECI
HSVKSRLAHDVDQIQLLKEQLIPTVPIEVRGTSSWKNWYKAE
>A0A2N2M4C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-1|TrEMBL
MQDNRFKEALLNPSVFPVTWELVPGRGARETAQDKALALAGQAASNSNIYALTLTDNPGG
TPAMSADFMGSEIVKLGIEPLVHFTCKDKNRNAMESSLYALDRAGVRNLLVMSGDYPVSG
YRGRPAPVFDLDPIHVLQLISDMNRGLEYPGMKGTIRHQPADFFAGAVVSPFKATEAEQI
IQYSKLKKKIEAGARFIVTQLGYDARKFHEVLLYMKQNSLDIPLIGNIYILPFGAAKMMN
HNDLPGSVVTDKLLADLDRERNDPDKGQGARILRAARMYAILKGMGFSGVHIGGHNIKYE
QVDAIIDMGESLTSQWKDLLQYFDYPINGGFYYYEKDPETGLNREVPVKLVDQLTDVKIG
CSYGFSRFFHRLMYEPGKNLYGFMKRLCGKVQETKTEGPFHKMEHLTKVALFDCRDCGDC
ALIDVAYLCPMSQCPKNQRNGACGGSYKGWCEVYPGKRHCIYVRAYARLKKYGEEGQLSR
EIVPPCNWDLYQTSSWINYYQGRDHTSQKLNDKSS
>A0A3D8UJD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp. HD9-500m-PIT-SAG03|TrEMBL
MLKNKIRNKKSGILFYGLTPPKATNTEEQIKVITQKHIDRILPLEIDGLILYDIQDESDR
TNKKRPFPFIKTLDSTDYANDYLNVLNLPIVVYKAVGKYDKKNMSSWLEESKKSNSYSVF
VGAASDTQKSKMSIKDAYALKKDINSDLVLGGITIPERHSKKKDEHLRVFSKTDNGCEFF
VSQAVYDLHASKKFLDDYSSYAKENNKEIVPIIFTLTPCGSVKTLEFMKWLGIHIPELLE
RKLMESGNILDDSVKFSIAIFESLYTYGLQKGIPIGCNVESVAIRKEEIDASIELLNEVQ
KIMKRHK
>A0A2A1ZT57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. NML 150383|TrEMBL
MRGTFAPTRLSASAPIDRVGEDTTQQRRRTRTALSFELIPPRHGADEGKLDELIAGLAAY
RPDYVSVTSSRRSDWLTGTAALIARVAETTNLRPIAHLACTAGTREELVTWIRTLIDAGV
RGFLALRGDLPETGMPADHLQHATDLLNLIQDVEDEEAFRLAAGKLALSVACYPSGHAES
KNFDEDLDVLLSKQRLGADFAITQLFFNAQDYLDFVEVARLAGVRIPLIPGIMPMTSLKR
VQRMGELSGIEVPERVARTLAQATTPEEEYELGMQMSARLANTILDAGTGGLHVYTHNNL
AVTQDLLSRIGIPQRADHSPQ
>A0A1Z9Q5G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium TMED229|TrEMBL
MVSALQRVLEAGAAAITAEVMPPRGGDASHTLAMATALKGRVHAINVTDGSRAVMRMSSL
AVCRLLLDAHLEPVLQLACRDRNRISLQADLLGAHALGIRNMLCLTGDPVRAGDQKDARP
VNEYESVKLLQQVRALNRGEDPVKGQLPDGPTQLFAGCAADPQSQSWSGLTRRLRRKCEA
GARFIQTQMVMDPAALERFQNELAGPMQLPVLAGVFLLKSAKNAQFINRVVPGACIPDDL
IQRLEDAKDPAMEGVAIAAEQVRRYLGVVQGVHLMAIKAEERVPLVLDQAGISSLPM
>A0A1E8CU63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Humibacillus sp. DSM 29435|TrEMBL
MAYGTASSMVRAERFTRSIPAMVDSDTPTFSFEFFPPKDDDAEVSLWDSIRRLEKLSPSF
VSITYGAGGATRDRTVKLTQRVLESTSLTPLAHLTCVGHSVGELRAIVGSYAAAGVRNIL
ALRGDPQGGLGQPWTAHPEGFDHADELVELVKGLGDFTVGVAAFPDGHPESHDIADDVET
LIRKEAAGAEFAVTQMVFDVESYLRLRDELTRRGSMLSVIPAIMPITNARQVVRMAELAG
QPMPTAVTDRLDRQGDDAVGVRAEGMAIATESSRRLLDEGAPGIHFITMNRSSATLEVFG
NL
>A0A0H3B8D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pseudotuberculosis serotype O:3 (strain YPIII)|TrEMBL
MERKLSFEMNSAKNEKEMENIFKLIEFTDTLDPIYYTVNTEIGSSVWSDTYRTVIELREK
TDVPLIPHITINNKKEREIMQIIEKYINVGICEFFVIRGDKHVYDQDNPINYGVELIELI
RRSHKHIGIKTSLYPDFHKETTEVKEEIDWNERKYQLGVNEFISQLTLNTNALDFLSHWV
DKERPFTPSIMPLGNFSFIEKFTSSNSIDYPLWIKKFANSKSNSNEDKENIGIEIIRFLC
REYLNQRERLHVFTLNKVDVMKKIFQ
>A0A2A3DZE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3859|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVIREFVDFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
AGSAAA
>A0A363TV79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobiaceae bacterium|TrEMBL
MSLAGRASRFAEGSRIRVSFEFFPPKTEEMERTLWEAITRLAPLAPRFVSVTYGAGGSTR
ERTHATVKRILAETRLVPAAHLTCVGATRAEVDAVIRAYAEAGVRHIVALRGDPPGGVGA
RYAPHPGGYENGADLVAGIKRLADIEVSVSAYPEKHPDSATVEADIDMLAAKVDAGATRA
ITQFFFENDLYFRYLDRVRARGIAIPVVPGILPVQNFKQARGFAERAGASVPDWLAARFQ
GLEDDPATRKLIAAAVAAEQVLDLVDRGVNDFHFYTMNRADLVYAICHLLGLRPEVKEAA
>A0A158CAN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia catudaia|TrEMBL
MPPPESLIIMKPIELSFEFFPPKTQEGVDKLRASRAELKKLSPKFVSVTFGAGGSTQQGT
LDNVLDMAAEGFEAAPHLSCIGSSKDNLRTILANYREHGIRHIVALRGDLPSGMGEVGEL
RYASELVAFIRQEHGDWFNIEVAAYPEFHPQSKSPRADLENFARKVKAGANSAITQYFFN
ADSYFKFVEEARKLGVDVPIVPGIMPITNFSQLMRFSDMCGAEVPKWIARRLESFGDDRE
SIRAFGVDVVSGLCRRLIDEGAPGLHFYTLNGAWASKTICERLGFKSA
>A0A1F2Z4W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium RIFCSPHIGHO2_02_FULL_46_13|TrEMBL
MLHIPISFEFFPPKTEAAAEVMLASATDLRGLNPEFVTVTCGACGSPKTGTFEAASRLKA
ELGFTTGVHISYFGTKKADLFEYAETLWEASTHHLVALRGDIPEGVNGADYNHGDYFQFT
SDFVEALMACRPFDISVGAYPEKHPDAPDMTADIKALKLKCGAGAKRAITQFFFGTDIYK
GFLEQVRGAGIETPIVPGLLPITDFEKAKAFAAKCGATIHPAIAERFLNSSDPQQTAIDL
LASQIDDLINLNVPQLHFYTLNRADLILSAFQKLGKI
>A0A1B7V077|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabaena sp. AL09|TrEMBL
MPDTHSFSAFNNFRKAALAGEFLITAEVAPPKGGDPVQMLSMAATLKGRVHAVNITDGSR
AVMRMSSLVASVILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPQAKAVFDLEAVRLLQLIRNMNQGFDLNEKPLTDGALDLFAGAAVDPQSQSWSGLQS
RFEKKIVAGAQFFQSQLITDFEILEKFMDKIAVGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEEGMKIAAEQVQIARGLCQGVHLMAVKREDLIAPILDLAGV
EKVS
>A0A2N2DQ47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-11|TrEMBL
MKIRDLYEQKKTVMSLEIFPPKLDSPVEVIYDTLDALSDLKPDFISVTYGAGGKAKDRTI
EIAAKIKNDYGIESVAHLTCISATKEQIKENFRTMREGNVENILAMRGDIPEDPDFEFPN
PLQYEHAADLIAEAHNERDFCIGGACYPEGHIDAVSKVQDIKYLKAKVDKGTDFLISQLF
FDNELFFRFMEEIDLAGINVPVSAGIMPVLNKKQILRITQLSGCSIPPKLQRILDRYEDN
PAAMKEAGEAFAIEQIIDLMAWGVRGIHLYTMNKPETARRIMGNIEAIRSLQG
>A6W6I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)|TrEMBL
MTLAPLVAGAAGRPVLSFELFPPRSESAREGLWRKLSDLLAARPDFVSVTFGAAGATRGP
SRDLLAHVLRTTAVPAMAHLTCVGSSRREVVDLASEFLDAGVRNVLALRGDPPAGDAGWT
PHPDGVATARDLVELLQVADRRRAALRGARVPVDEGPLSLAVAAFPRGGEGELAALRAKQ
DAGADFAVCQVTFSAGEYAAFVRRARAAGVRIPLLPGVAVTDCTRRLGRIGELTGVPVPV
PLLAALDTDDAPRRRRAATAFTAGLARGLLDAGAPGVHLYTFNAAEPALDLLDDLDLPRS
LDPIRASTAAAAGGPAR
>A0A7U9P2R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus PSP1996|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLYGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A0M9BJG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus xylanivorans|TrEMBL
MKADLRSVMQERVLIGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
HETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGPNGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGASPEYFGQTAVQFADLGARIIGGCCGTTPDHIAAIAQALVEYTPVPILEPDPSE
SKPRIILHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVSFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
SMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A7W0EME1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MLVKDIIARRQPTMSLEFFPPKTDDGWERLFMSIAELIPLKPAYLSVTYGAGGTTREHTH
NLVGRIQRETNITVVSHLTCVGHSQGEMRSILDRFQQSGVENILALRGDPPKGQEDSVQP
KDGFLYAAELVAFIKENFPNMCVGVAGFPEGHPGTPNRLREIEYLKAKVDAGADYIVAQL
FFDNRDFYDFCGRCELAGITVPIIAGIMPITSRQGMVRMAELAAGSRIPAKLLKAVERAG
SDEQVAKVGVHWATEQVRDLLDHGVRGIHFYTLNNSSEILKIYEALGVSDSDQLSS
>A0A7H8RHQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium lividum|TrEMBL
MGHLLMHPAQLRAAGHITHAYSLEVSAKDMPALSTAAPRIAPASTIAIPYLPREDNDARL
AAARTVRNLGFEPMLHLSARRIASLAEFESFIQRAVAEAGVERCFVIAGDPSTAMGPFSD
SAALIDTGIFERAGMQVIGVGGHPEGHPVMSTAEQWEVLERKCDSIGKRGMAPLIVTQFA
FDADIVLTWLKTLRERGIDHPVRVGVPGPASIAVLARYAAVCGVSACASMWSKYGVSIGK
LFGTAGPDLFVERLANGLTEAHGEVSLHFFPFGGIAQSVNWIEQYRARTGPGP
>A0A6L4ARD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MNTETHVASGSNLEKVLRSGQFAFTGELGPPRGTNADEVREKAKFLKGNVDAVNITDNQT
AVVRMSSWAASLIAIQEGLEPNYQMVCRDRNRLAMQSDILGGYALGIRNMLCLSGDHQQF
GDHPDAMGVFDIDSIQLIAMVRQMRDEGLFLSGTEIHQPPKMFIGAASNPFADPFEWRVH
RLAKKIEAGANFIQTQCIYNMEKFRKFIHLANEEGLTEKVFILAGVTPMKSVGMARYMKS
KVPGMDVPDEIIDRLKGVEKEKVAQEGINIACEQIEEFKEMKGVHGVHLMAIEWEHMVPQ
IAEQAKVLPRPVFS
>A0A525D738|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKSGSNLERVLSAGHFSVTAECGPPRGADPDVVREKAAYVKDNVDACNVTDNQTSVVRMS
SLAGCMLVRETGVEPLIQMVVRDRNRIALQSDLLGASALGVRNLLCLSGDHQKFGDDPQA
KNVFDIDSMQLIHMVKTMRDEGVFPSGEKLEGAPKFYIGCAVNPFADPYDIRVPRLKLKI
DAGADFVQTQCIYNMETFIKYMEDAKKEGLHEKIKILAGVTPLKSAGMAKFMNRMVAGID
IPEAVIKRIADEPKEKQAEKGIEMCIEQIHELKEMEGIAGVHVMAIEWEEKLNEIIGGAG
LLPRPVIE
>S4GYL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis JCP7672|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIHSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKISEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A0S2NYI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces hygroscopicus subsp. limoneus|TrEMBL
MSDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVKE
TQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVPHP
RGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFF
QPESYLRLRDRVAVAGCETPVIPEVLPVTSVKMLERLPKLSNAHVPDALKERILTAKDDP
AAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>T0V9U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HSISS2|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILLALEDMKGLSPHFISVTASNNKYNIKETTVPLANH
IQNDLAIPTIAHLPAIYLTKEKVADTLRELDAVGVHRILALRGDIIPGVEPLKDFTYATD
LIEFIKEKAPQFDIVGACYPEGHPDSPNQISDIQNLKKKVDSGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAATARHIYNATHALFKSHSNSEK
>A0A353NHC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKSGSNLEKVLAAGHFSVTAECGPPRGADPEVVRKKAAYVKGNVDACNVTDNQTSVVRMS
SLAGCLLIKEEGIEPLIQMVVRDRNRIALQSDLLGASAMGVRNILCLSGDHQKFGDDPQA
KNVFDIDSMQFIHLVKSMRDEGTFPSGKKLDGAPKFFIGCAVNPFADPFEIRVPRLKLKV
EAGADFVQTQCIYNMKKFKEYLELAKKQGLHEKVKILAGVTPLKSAGMAKFMKKMVAGMD
IPDEVINRIAAEPKEKQAEKGIEMCIELIQELKEMEGIAGVHVMAIEWEEKLHEIIGGAG
LLPRPVVE
>A0A2S1SGP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium pallidum|TrEMBL
MKVTQHIENAQGKSLFSFEILPPLKGQNIRSIFDSIDPLMEFNPPFIDVTYHREEFEFKE
LGNGLLEKKIVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDIDFLGIQN
VVALRGDAIKSEIYFRPEKEGHHYASELVTQIDNLNKGIYLDPDLQNSAQTDFCIGVAGY
PEKHMEAPSPDSDIYFLKQKIRNGAEYIITQMFFDNKKYFDFVAKCRAEGITVPIIPGLK
PIATKKQLNMIPHRFKVDLPDELIMSVVKAKDNDAVKQIGIEWCIQQSQELLKAGIPVLH
YYSMGKAENIKAIAKEVF
>A0A1Z7ZTG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium 42_54_T18|TrEMBL
MLIEKIKNRESGIVLYGITPPKKGTSSEKIEDISARQIQRLQGLNVDGLILYDIQDEKSR
TSEERPFPYMETLDAYSYSEKHLSSLAIPKVIYRSVGKYSESELREFMTSASPEEVLTVF
VGSPSKNQGVTLTMNEAYQLRKDANSNILLGGVTISERHQSKGDEHIRVFNKIAQGCSFF
VSQGVYDVNASKDFLSEYYYYGLEHNIPLVPILFTLTPCGSLKTLQFMKWLGISVPKWLE
NDLVHSKDILQKSVDFCEQSWRELKQFADEKGIPVGCNIESVAIRKVEVDASIDLLRRIS
>A0A520ZW48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MAATVTGSKLEKILKSGHQAVTSECGPPRSSDPAHIKEKGELIKDHVDSINVTDNQTSVT
RLCSLAACIHLKGMGLDPVLQMVVRDRNRIALQSDILGAASFGINNILCLSGDHQSFGDS
PQASNVFDLDSMQLVQTVRYMRDEGKFLSGDEIKAPPDMFVGAAANPFGDPFKIRVPRLA
KKVASGAEFIQTQCIYNLDKFEKWMEGVRARGLHEEVYILAGITPLRSVGMARYLQKNVP
GMDVPDELIERMKGVDKKKQSDEGINIAIESIQRLKEVEGVAGFHVMAIEWEEKVPEIVE
RSGLYPRPQID
>A0A2N6C6G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MLVKDIINSKKTCISYEFFPPKLEKDWDRLFQTISDLIPLEPAYVSVTYGAGGSTRDRTH
DLLVRIQKETDLTVVSHLTCVGSNRDDIHAILSKYTENGIKNILALRGDLPKGQTHWEQP
ENGFTYAAELVAYIKKHFPQMGIGVAGFPEGHPETPNRLKEIEYLKAKVDAGAEYIVTQL
FFDNRDFYDFRERCELAHINVPIIAGIMPITTRKGMIRMAELAAGARIPARLLKAVERAG
SDEYLERVGVHWATEQVRDLIDNNVRGIHLYTLNCSTATLRIYKSLGISSSTQL
>A0A7W7AQ20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides faecis|TrEMBL
MKVIDLINGSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFNPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQNTDLYHEHATGLQQQVNNFNKGIAIDGSTFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVDRCRAEGITVPIIPGIKPV
VFKTQLTVLPKIFRSDIPEPFAAELRKCKNDDEVKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMATDSVYKVAKEVY
>A0A6S7B655|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararobbsia alpina|TrEMBL
MAATELSFEFFPPKTADGLDKLRATRAQLATLKPKFVSVTFGAGGTTQQGTLDLVVEMKR
DGLEAAPHLSCIGASRESIRQILEHYRENQIRHIVALRGDMPSGMGEMGEFRHASDLIEF
IRAETGNWFHIEVAAYPEYHPQARSPRHDLEAFAHKVKVGADSAITQYFFNADAYFRFVD
DVRKLGVEVPITPGIMPITNFSQLMRFSDMCGAEVPRWIAKRLESYGDDRESIRAFGADV
VTDLCRRLLERGVPGLHFYTLNTASASRTICERLAL
>A0A1G0AAA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon RBG_19FT_COMBO_69_17|TrEMBL
MAEQVGTRQLRVGSRLEWVLASGAFAVTAEIAPPASASPEDVRRAAALFRGHVDACNVTD
SQRAQVKMSALAASALAAQEGVEPIMQMVLRDRNRIALQADLLGAAALGIRNVLCLRGDD
PQVGNERDAAPVYDLTTEEMISTFRRLRDGGLLRGGDKVEAPPKILIGAAANPFGGSLEE
SFANLRGKVTAGADFIQTQAIYDVDAFEEWMRLVRKEWLHERVYILPGVIPLRSPKMAKF
MAEKVPGVVIPKDILERMHSAPDPKQEGASIALRTIKALRKVEGVAGVHIMAVNWEEIVP
ALVRDAGLHPRPEVPTPPP
>A0A6M0LGI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio xylanivorans|TrEMBL
MFREMLSRDASMSFEVFPPKKNDEFDNCYNVLDSLAKLNPDFISVTYGAGGSRSKKTVEI
ASYIQNTLKIDAMAHMTCVGSSEDDILEVTKDLEASGVSHVLALRGDKPRDMSDEQFAKR
IFPHATDLIRFLNTNTNLDVSAACYPEKHPEAMSIDSDLAFMKMKQDMGAKMFISQLFFD
NADFYRFVERADKAEIHVPIVAGIMPITSAKQIGSTVTLAGSSVPKKLADICAKYGDFPE
DMRKAGIEYAIDQIRDLRKCGMGHIHLYCMNKPKMTEIICKSI
>A0A842KNT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomethylovorans sp|TrEMBL
MSFTFRDKLQSGRFIITTEITPPKGVETSSFLTAAEQLKQYVDAFNVTDNQRSVMRMCPM
AVGKLLIDAGHESIIQITCRDRNRLALQSDLLGAWALGMQNICVMTGDHTTKGDHPGAKP
VFDLDSVQLLNTIRKLNNGYDLCGNRLKEAPDFVVGAVTNADIGQAMQYIKLRKKISIGL
DFIQTQAVYNVEDFSLFIEKVNDFDVPVIAGVIPLSSEKMARFINNNIPGIKIPDEYIMR
MENALEPVQEGLEIAAEIIRELKSMCRGIHLMPIGQHTHTKELLKMSGLKKGR
>A0A2A5V4A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterales bacterium MED-G39|TrEMBL
MNFSLEIGPNTDVDAVPALSDVYITMLPGGDYRETAEKASELVKKGFNPVPHFPARSMHD
ANELKDYVSRCKDGGVKQVLIIGGGRDPAGKFESSFQLLETGYFEKMKIGIAGHPEGSPD
ISDSELEKAMIDKKPYADYIVTQWLLDPQPIIDFISKQSVPVHVGITGPLKISSLIKFAN
IVGAKNSINFLKSNFTKALDLLKPKDPNDLIGKVKSHTDNFHIYTFGGLKETNKWLKENS
YV
>A0A0M4RG97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. animalis|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSLEKPDYISVTYGAGGNTKGRTV
EIADRIKRQNGLESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEKGD
FNYARELIEYIHKKKGDKFSIGAAYYVEGHRETNDVLDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPRKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRRE
>A0A351L8D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium UBA11371|TrEMBL
MLNHQSPKVLNSFRAAVNAGEFLVTAEVMPPKGGNPAHMVKMAQLLKNRVHAVNITDGSR
AVLRMCPLAASMILLQQGIEPICQMACRDRNRIALQADLMGAHALGIRNILALTGDPVKA
GDHPDCKGVFDLEAVRLLKTIDKMNRGFDWNDKPLTDGATDLFVGAAVDPHCASWSGLQQ
RFERKLEAGAQFFQSQLVTDFDRLEKFMDQIAAGTNKPILVGIFLLKSAKNAQFINRCVP
GVNIPQHIIDRLAAAKDPLEEGMKIAAEQVQHARQLCHGVHMMAVKREDLIPQILDMAGI
APLSVAHPVTVGV
>A0A2L0SNQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas acidaminiphila|TrEMBL
MTALSFEFYPPKTDDQRAQLDRTASRLKVHAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLQAAPHLSCVGGTREEIRELLKLYRAIGVRRIVALRGDLPSGMGFPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLRHFKAKIDAGADAAITQYFYNADAYFQFVDA
TRRLGVDVPIIPGVMPISNFSQLRRFSEQCGAEIPRWIAKRMQAYGDDVDSVRAFGADVV
AALCERLIAGGAPALHFYTLNLARPTNAVLQRLGRG
>F2I7G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aerococcus urinae (strain ACS-120-V-Col10a)|TrEMBL
MKTKELFKGKTLFTYEVFPPNAKSSSASIYKTLDGLKELDPDAISVTCGALGSDNRLKSI
EIASLIKNYGIESVIHLPCLYETRASIDEKLAELKAANIENILVLRGDPKPGQSPKEDFP
YAADLIRYIKSKEDFNLIAACYPEGHVDAPDPITDIRYLKEKVDAGSDQLISQLFLDNDY
FYRFLERADLAGIDVPIEAGIMPVTNKKQIESMARICGVQIPDKFRRAMEKYQDNPLALR
DAGLAYAIDQIVDLISHGVDGIHLYTMNNPYVARYIYQAVKNLL
>A0A0A1VTR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa NIES-44|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A8G1JFB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDRTLSTVLQL
DGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMASGELRYANE
LVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQYFFNADAYF
YFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSRSIQAF
GEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKSLQLPR
>A0A6J4QH01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Rubrobacteraceae bacterium|TrEMBL
MSFDLREMVGSRVLIGDGATGTLLAERGVGFGHPYARANMTHPDMVAGIHEEYIRAGAGV
VETNTFSANRFKLEVHDLEERVREVNEAGARLARKAADTAKAAEGHKALVFGAIGPLGRP
LCPVGPVTGAEARSAFLEQAEALLEGGADALVLETFTDLLELGLAHEAVRGLGIPIVAYK
TFVEDGETLAEGLPGRAALEICGLGVDLAGANCTVGPQRMVGIIEGMSAEVGPVAAFPNP
GLPQLVDGKVRFRRDVDHFAVYGRRLAEAGARLVGGCCGTTPEHVKALAEALRDFRPVAG
PGGRGVRARTVEEVGSEEVPGGPSTELAEKLRTGFAVAVEVDLPRGNDIAKVVEASRRLK
ERGVDAIDISDGARARLRMHPVAAAKIVQDEVGIEAVAHISCRDRNIIGLQSDFLGAAAL
GVKNILAVTGDPTQIGDYPEATGVFDTDSVGLVHVLSKMNRGEDLAGNPIGEPAGFLIGS
AFNPTAGDLDGEIEKLRRKIGAGAHAFWTQPVFEIGALEIALERMGDLEACLLLGLMPLR
SARQAEFLHHEVPGVDIPKHVRAKLADLSCEDAPKYGVEVAQNLLSRARPLVNGAYIMPP
ASAPDLAGDVIEALNLRLQPSARTAKADR
>A0A7K3S0R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces parvus|TrEMBL
MALGTASTRTDHARTVREMLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>E6VK07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas palustris (strain DX-1)|TrEMBL
MSDLPQQLPAISFEFFPPKTEEMERNLWQAISRLAPLHPSFVSVTYGAGGSTRERTHATI
ARILKETDLTPAAHLTCVDAPCGDVDEVVTRYHDIGVRHIVALRGDPTTGLGGTYTPHPQ
GYRSSADLVASIKRRYPDIDVTVSAYPEKHPESTGFDADLDILKAKVDAGATRAITQFFF
DNDLYFRYLDRVRARGIDIPIVPGILPVQNFKQAAGFAARAGASVPDWLAKQFEGLDDDP
DTRKLVAATVAAGQVHKLAKHGVNNFHFYTMNRADLVFAISHLLGFRPQAARQAA
>A0A062GS66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 72431|TrEMBL
MSHISPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDIIDKVLHFSGKARDIQDFELFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANYMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVK
TGKEFIPEITRFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENSLVAK
VLIKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVAQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A7Y9F333|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides marinisabuli|TrEMBL
MTIGRGRALTDLIAAGERSFSFEFFPPKDEAGETQLWDAVRALEPYRPTFVSVTYGAGGS
SRGTTVRLTGRIARETSMLPMAHLTCVGHTRGELEQILDEYAAAGVHHVMALRGDPEAGP
RAEWTSTEGGLDHADELVELVAARREFRIGVAAFPERHPSSASLEQDADVLAAKARAGAE
FAVTQMFFRASDYFSLVERVRARGVDLPILPGIMPILNLQAIRRQGELIGTDVPADVVER
ISAHEGDPVSMRAEGITQAAELCQELLDGGAPGLHFYTLNRSKATREIFEKLDVTP
>A0A558HRS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia crustatorum|TrEMBL
MSASEHPLGISFEFFPPNTEVGHEKLMDVRDRLAVIDPTFFSVTYGAGGSTRKRTFNTVN
AVSSSGVCTAPHLSCIGSDRGELREILSEYRERGVKRLVALRGDLPSGMGARSELRYANE
LVEFVREETGDHFEIAVAAYPECHPQADNYQRDLENFARKMNAGANIAITQYFFTADAYF
HFVERARAIGIEQPIIPGIMPITNYTKLARFSDSCGADIPRWVRKQLESYGDDSESIQKF
GTEVISRMSERLLDGGAPGLHFYTLNQAEPSLNVLRNLGITSA
>A0A1X1J4K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. dentisani|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETLVDLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIRNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1E7LMA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces nanshensis|TrEMBL
MALGTASTRTDHARTVRDMLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHRQS
>A0A2K9A284|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. Pdp11|TrEMBL
MAFHHAQHSQSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPRPTRFAADLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPNWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A0D0N147|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora griseola|TrEMBL
MRDLLAAGDRSFSFEFMPPRSEEGERKLWDAIRRVEALDPNFVCMTYGAGGSSRGRTVNL
VGRIATETTLTPVAHLTAVDHSVAELRNIIGQYADEGVRNVLAVRGDPPGDPMGEWVRHP
DGVSYAYELVELIKGIGDFCVGVAAFPQMHPRSTEWDEDIKHFVAKCRAGADYAITQMFF
EVEDYLRLRDRVAAAGCETPIIPEIMPVTNIRQLIRFPQLSGSDFPPEFRRRLEAAAENP
AEVRAVGLEHATAMAERLLAEGAPGLHFITLNHSTSTLEIYQNLGLNKH
>R5NFX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum CAG:69|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>X0RGQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. JCM 18903|TrEMBL
MLTDFPALMTLADRVHSDQDMSPLDASFFYPAGIDKVLHFAGKDRDIQDFYKFLDQANSA
NIQNLLLLTGDKLKNHVDEDSYLKRTRYLESVNAVMTAKQHGGFNIGVAFNPFKYNEAEH
DAQYFKLHKKIHAGADFIITQLAMTLTP
>A0A2W6DA79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MDLIDRIADGSGEFLLFALTPPRLSSAGDRAQEIADATIARLRPLELDGLVLYDIADEAA
RNPAERPFPFMPTLDPAAFLADNLTGWRGPVVIYRAVNKYSRPELQAWLADQDPSRVMAV
LVGAASSHTRPVTSLPEAQALSREVNPRLFLGGVAIPERHTLRDDEHLRLLTKQDAGSRF
FVTQVVYDVNAARNLVSDYHYACAARGTAAAPIVFTFSVCGSMRTLEFLRWLGIDVPRWI
ENDLRHATDTLEASYELALATATDLIAFCRNLGIPFGINVESVSIRRVEIEMAVRLAEQL
EALLRRRAE
>A0A6H0ZWS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. JQ2195|TrEMBL
MRNKLDGGGRTRNQTMRRLLEQARYEVLPTASTEEKVVEHVPLDRVITVTASPSKGLDAT
FDLAERLTRAGYAVVPHLAARMVSGRSELEEICDRLTSAGISRIFVPGGDAEPAGDYPDA
LSLLEDIVALGRPFNHVGITGYPESHPSISDDLTVQAMWDKRRHATHIVSNLTFDPAVIK
VWLERMRNRGVTTPLLLGIPGPVDRAKLLGMATRIGVGESTRFLAKHKGTFARLAAPGGF
TGERFLARCAPALGTPTAFVEGLHVFTFNQIAETEAWRTDLLQRL
>A0A6C1RNM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MKQHLLTSAYHVEILPPKQETEKLYEDLDRFSSKFERVMQSGYCACITDNAMGNLAFQGT
ELIEELELEAGRNQVMIHLNTFHTKADLHRILDSCKAAGIRQLLVITGDGSDRLPRLTPA
EVGAEGVEAVTSVELLRYIGETYPGDFDLGVAFNPYEPEDHEFSKLDRKIAAGATFAITQ
PIIERHPVVDKLIESYPDLPVVVEAWMSKKISLLSEAVGYEISEDTPYDPIENLKTLHRN
YPQCEIYLSILGFKTQYPLLEEIRN
>A0A662Q489|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MRWNRLKADSKLERILESGEFAVTAEIGPPKSADAEVIRRKARTLKGYIDAFNVTDGQTA
VVRMASWAACLIGKEEGLEPIVQMTCRDRNQIAFQMDILGVAALGIKNLLRLTGDHVTV
>A0A2N1JDZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malassezia vespertilionis|TrEMBL
MDPPRYDDDSDMESQDDHWTNVHLGLADGELEQGDEENPLVSRIGGRPAWLPLAPQNLPQ
ESLILLVEIFAPLENSAYDRDLLVWGCANAVCQRVEAGSVRVIRMLKYNTRWAAKLEKKK
QKQAVRVARVAERKQQEQDAETERVRRELEKNPFTMSDNPKAQSLFTSSLFANAPSHENS
APENAQSPMDDDDDDDDDDDDDDEDDEDDYDEEARLAEEEAIKQSIAAQREQLGLDKDWA
RSVTQYTPPLYLNTISEPATQEETLQAPAESVIQRAAELSADASLSGKEEYEKMVLDGID
STFERFTRRIRAEPRQVVRYEFGGVPLPFSAQGSIFRMLWPDPQKPMREDAVPPCPLCGA
PRVFEMQLMPNLANLLRAERIDDTDVQQPKDAAEAEKQRRAQIENTLGLGSAKDGRRVAR
IDEKLAQKQDGILWSLEFFPPKTSDGMANLYARIERMTAKLHPGWVHVTWGSGGSTRDIS
LELAVRVQNGFFDPSMNWRAELDNSGPRTGGCDVCLHMTCTDVERSFLDTALADAKRYGI
CNILALRGDPPRGEESWIATDQQFQTSIDLVKYVRKQHGDAFCIGVAGYPEGLSGHTPED
VARDIGFLKQKQDAGAQFIVTQFFYEPEKFHTWHARCRAHGITIPIIPGVMPIQNYHSFR
RMTNLCRLQVPTPLLEALEPIKTDDASVKDVGVQVAHTIVDQVHKQDQIAAFHLYTLNLE
KSVTRVITGAKAGAGELRAEKGALVRSPADWEWDEFPNGRYGDSRSPAFGELDGYGASLK
VPPEEAMRLWGTPVDESDIRRIFTNYVKGSLACIPWCDVPVWDETAPLLPALTRLNDGKG
WWTVGSQPAVNGIDSSDPTYGFGPKNGFIFQKSFVEMFMSEKDKRALVERIGQSETPITF
YAAMHDPASFETNVGEHGLNAVTWGVFPGKEVAQSTIIEAQSFMAWRDEAFAIWREWELL
FPPRSASRKFLRAIHDTYWLVTVVHHDYKDADGLWRFLTQA
>A0A812QRW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiodinium sp. KB8|TrEMBL
MATKIVDLVKAKEEAKEPFVAFEYFPPRTDKGLENLYRRVQLMKHQAPMYVDVTWGAGGS
TSDLTLDMCVKMKTEYGLEPNMHLTCTNMEAEKVDIALEGAKAANIANIVALRGDPPKGQ
EEWTATEGGFTCALDLIKYIREKHGDYFCLSTAGYPEGHPNVIKEVADASSLSESEKGRL
VELDGKQFVCSDEDYGKEMAYLKAKVDAGADMIITQMFFDVPVFLTFVQDCRDAGITVPI
VPGLMVIQAYGGFNRMTAFCKSRVPAWVRDSLEAVKDDEAAVKAQGIAIGTKMCQDLLAA
GVVPLHFYCLNQEKATFAIMENLGMLKAAAEEEGATAAAAEATASA
>A0A2S6UVN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha2_Bin1|TrEMBL
MNNINKNTSKLNEALAKKKFVITAETTPKTDTDLNASLEKVLYLKGLADAVNITDGAGAK
SHLSSLVLSGVMKSNGIEPIIQLTLRDKNRIAIQSDIIGASAMGVTNFLVLTGDPAEVGD
EKQAKFVGDFEQSTDLISLLTKINNTGELNSGRNITNPPEIFLGAADAPFLPPSNWKPDK
LIAKVNSGAQFFQTQYCFDMKICKKYFSILSDFGLLKSVYFLVGIGPFSSSKQAIWMHEN
LPGVEVPDRILNILSKSKDQKGDGKKICLELLNELHEIDGVSGAHIMGPGQEQTVAEIIQ
AIRK
>A0A0M2DI42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp. E6|TrEMBL
MTQDSETYTAMSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPEFCSVTYGAGGSTQAGT
FTMVRDIQNEGVGAASHFSCIGATHEKVRAELNELKAMGVKRIVALRGDLPSGYGLGGEF
QYASDLVAFVRQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYN
ADAYMRFVDEVRALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFEDDTA
SIRAFGLDVVTHLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A044RB71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Onchocerca volvulus|TrEMBL
MDTITDHVTADDEAGTSTTKNDNGCVIDSSEITNQAAISSHQWSESRTDWVTHGTYVPLR
DRIKKRIADGVPFFSLEFFPPKTANSVANFFARLDRFREGNPLFVDIAWHFGSDPGNIHS
ETSSTSVAAGCLDYCGMDTVLHITCCPYTKEQSIRHLEQSKALGLKNILALRGDLPRQDE
NPVLYKYRALDLIRWIKEEYKDYFTIACSGYPAGHPEAPSYRADLLYLKAKVDAGADFII
SQIIFDGQVFEKFLRDCREIGITVPIIPGILPIQSYESIRRIAELSQLIIPDSILASLEP
IKNDDDAVRNFGIRYAVDLCQTLFTNGSATSIHLFTLNREASSREILQQLGLWSRSPVRA
LPWRSFGENHPVRCKEDVRPIFWSLRPKSYVFRTREWDEFPNGRWGNSSSPAFNDLKDYY
LFYLKGQPTKVEQLRMYGERLETLADVQKVFINFIAQNINENGVKVNQLPWNEQYDGIRA
ETSLIKDQLLWCNSNGFLTINSQPSVNGAPSTDPFVGWGKPGGYCYQKAYLEFFTSQANA
EVLWNLLPSYSRLNCHIVNHDATIDWTNTETTMPIAVTWGVFPGSEIAQPTVVDPLSFRV
WKDEAFDAWLNWSSIYAEGTSSRCLLEKIYNEYCLVTLVDNDYPKSTIIFDCLAQLVSKN
FGEIL
>A0A157SN13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella ansorpii|TrEMBL
MSLIHPGLSTPSPGTITDGYSLEVSARDITALTAAASRIVPGSTIAIPYLPGQDNDARLA
AARAVRGLGLEPMPHLSARRIASLAELDCFVRRAVAEAGVDRCFVIAGDPPAPLGPFPDS
ASLIETGVFERSGIRVVGVGGHPEGHPVMSEAQRWEVLDRKCHGIAARGMTPMIVTQFGF
DADAVLTWLETLRERGIEYPVRVGVPGPAGIAVLARYAALCGVSACASMWSKYGISLGRL
FGAAGPDVFVDRLATGLTQGHGAVSLHFFPFGGIAQSVGWVERYRARAGHRASA
>A0A2T6KJN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yoonia sediminilitoris|TrEMBL
MSAPAVSFEFFPPKSLAGSFRLWDCVNTLAPLDPTFVSVTYGAGGTTRKLTHEAVSTIHR
TSGLNVAAHLTCVDATRQETLEIASAYADAGVTETVALRGDAPKGSAKFTPNPEGFASSV
ELISALADTGKFQIRVGAYPEKHPEAADQAADIAFLKRKIDAGACSAITQFFFEAETFFR
FRDACVKAGIDAPIIPGILPIENWKGTQKFAAQCGTAIPQIIHDAFTNAERDGTCDLLAT
ALATELCDDLRQGGVDHLHFYTLNKPELTRDVCHALGVTPKVRLQNVA
>A3VMB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritimibacter alkaliphilus HTCC2654|TrEMBL
MKAPRISFEFFPPKNIESTFRLSDTVRDLAPLDPSFVSVTYGAGGTTRELTHDVVATIHK
NYGLNVAAHLTCVNATRDETMEIIDNYARVGVSEIVALRGDPPKGSNGFVPHPDGFANSV
ELIEAIAARGDMKIRVGAYPDPHPEAASDTADVDWLKRKIDAGATSAITQFFFEAETFLR
FRDKCAAAGIDAPIIPGILPIQSWTGVKNFAKSCGTPVPGYLDDAFLRAERDGRERLLSI
SLTTELCTELMEEGVEDLHFYTLNKTDITRDIVHALGVTPKVALQQVA
>A0A553WBK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingorhabdus contaminans|TrEMBL
MIFPLAQMQEASRALAEPLFAGLPGDCEISFEFFPPKTEKMEEQLWDSVITLAPLAPRFV
SVTYGAGGSTRERTHSTVARIARETSIPAAAHLTCVEATKDEIAEVAHAYWEAGVRHIVA
LRGDSPTADGKFTPHPDGYASAAELVEGLQKIHPFEISVSAYPETHPEAASAATDIDFLK
RKLDAGASRAITQFFFEPETFFRFRDAVAAAGINAEIVPGIMPVSNFAAITRMSNMTGTA
IPAWMAHLFEGLDDHPPARQLVAATVAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GKRPVSSAQEKAA
>A0A1G8GUB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium taeanense|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYRNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTNGGHASAMDLVHQINNLGRGKYLHNEDQECDEHNKFCVGVAG
YPEKHIEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVKKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEELINEVENAKNNESVKQIGIEWAINQCRELLDFGVPVL
HFYSMGKSDNIKKVAGALF
>A0A194S994|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodotorula graminis (strain WP1)|TrEMBL
MSGTSTPELRQPQSQRVSDRIAQLSPDQPFYTFEVFPPKTDIGLANLVDRIDRMSSLNPT
WMHVTWGAGGSTQARSLELAGASQGMGLETCLHLTCTNLEEGVLDKTLKRAKELGVVNLL
ALRGDPPRGEEYWTASSDMFQHATDLVRHIRKEHGDAFCIGVAGYPEGHADSPDKLADIE
YLFEKQQAGADFVVTQLFYDVDVFMKWYKACRDRGITIPILPGIMPIQNYLSFRRMTNLC
GTHIPDDIMADLERIQHDDAAVKDYGVRLSVKMMRALFDEGIRGYHLCTLNLEKSVTRVL
ELLEWVEPDATRHKPRLHRTLAPNGAPLPKVVNSLRPRPDSSQSVAGPDIARKDSPASWD
EFPNGRFGDARSPAYGEMDGYGVSLKLPPGEAMRLWGEPTSLPDISRVFSSYLRGTLPSN
PWSEEPLRAETATISAHLIEMNDERHWWTVGSQPAVDGAPSADLVHGFGPKGGYVYQKAF
VEFFLTGPELDELERKSAEDARVRRESGEGDDALVTWFAGNAQGEHRSNMAKGDVNAVTW
GVFGAKEIVTTTLIEEMSFRAWCEEAFALWREWSLLYAVASPARAFLRNVTETRWLVSVV
HHDYKDRDGLWKWLLALKTPQQDEA
>A0A0M9GQ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ahrensia marina|TrEMBL
MNPVDTNPLDAGAPLDPLPGHSSRGRLERVLRRGEFAVTSELNPPDSADPNEVYERASIF
EGWVDGINAVDASGANCHMSSVAICALLTRMGYAPILQIACRDKNRIAIQGDILGASAMG
VQNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETARSMRDDERFLSGRKITYPPNVFLGA
AINPFAPPYDFRPMRLKKKIEAGAQFVQSQYCYDVPMFREYMKRVVDMGLNEQCFIMAGV
GPLASAKTARWMRSNVPGVHIPDHIIKRLEGAEKQKAEGKRLCIEIMQEIKEIEGVSGVH
VMAYRQEEFVAEIVHDSGVLKGRQPWKREPLADSAIVAERMEELVDEQKQIPAEMAENAA
SNT
>A0A1Q4RZ07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix sp. HK-06|TrEMBL
MLIVMLDTLTPITPVKVSSFRAAARNGEFLVTAEVCPPKGGNPQHMLQMAATLKGRVHAV
NITDGSRAVLRMSSLVASAILLQNGIEPICQLACRDKNRIGLQADLMGAHALGIQNILAL
TGDPVKAGDHPDCKAVFDLEAVRLLQVIQKLNLGIDYNDKPLTDGALDLFVGAAVDPQCK
SWSGLQSRFEKKVEAGAQFFQSQLITDFDILEKFMDTIAAGCNKPILAGIFLLKSAKNAE
FINRAVPGVNIPQYIIDRLAQAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIAP
ILDMAGVTAVK
>A0A7X2XU85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Secundilactobacillus folii|TrEMBL
MKVVDCFEERPVLSFEIFPPRANASEKALDRFYNCLETLAKLQPAYISVTYGAGGGDNKS
GTLDLCRYIKEKYDIEAVAHIPGINFTHESVKQYLDQLQAAHVDNILALRGDLPKDGVIK
GDFKYASDLVTEIKQLGDFNIIGACYPDVHPEAKDSLTDIQNLKIKVDAGVSQLITQLFF
ENEHFYQFLDRCDLANIKIPIQAGIMPVINERQIKRMATMNGVGLPQKFLKMMAHYQDNP
VAMRDAGTAYAVDQIVDLLSEGVDGVHLYTMDNPVVTQRICSAIETLI
>A0A7L4ZZB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter busanensis|TrEMBL
MKVTDHLARANGKTLFSFEVLPPRKGENIQTLFSNIEPLLEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDT
VLALRGDPIKSEGSFKPQPDGHAYACDLIGQVANLNKGEYLDEEQDDTFATDFCIGTAGY
PEKHFEAPNHAADVRYLKHKVDRGADYIVTQMFFDNAKFFEYVAQCRAAGITVPIIPGLK
PLTGKKQLTALPRSFFINLPEELVEAVAQCRDDAAAREIGIEWCIQQSRELMAAGVPSLH
YYSMGKSETIRRVAAALF
>A0A855HIW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. UMB0918|TrEMBL
MTTAHLYKGYKPGQQVAHPTVSFELFPPRSASKLSSIWAGVDRLIAAAPDYVSVTYGASG
AKVDTRDTSVRVLTRVLDRHPGLPAVSHLTCVGATRGQLAMTIRLLLRAGIRDFLALRGD
PPAGQSEFEVVPGGLASAAELVALIREIAADTLPDGVGTGPNGAGADSAPNPKNYVSIAV
AAYPASSGEYRRNDIAALLEKELAGADYAITQVFYDPNEYASLVRELTIAGGRLPIVPGI
IPLTDLKRLNALEKIAGVTVPEEVSRTLQITDARERVAKSLRATLNLIDGVLAAGAPGVH
LYTFNRPRPALDVVEYVRASGYRNGRMPKRGEIDTELVDLALHRLTPSN
>U4LHN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyronema omphalodes (strain CBS 100304)|TrEMBL
MQKITDKITALPPGEAFHSLEFFPPKTEMGFQNLTARLERMASALRPLFVTVTWGAGGST
SAKSLQLAEVCQKHLQLTTCLHLTCTNMSKKLLDEALESAKKIGIRNILALRGDPPRNDE
YFNPPTEDDDGRREFVWAVDLVKYIREQYGDYFCIGVAAYPEGYAEGTCPEHQDPKLDLP
YLVEKVKAGADFIMTQLFYDVEKYMSFESLLRNEESGALKDIVILPGLMPIQNYHILRRT
TKLSNASLPAAIQDRLEKIKTDDAAVKSAGITILSEIISQLRSSPLSPRNPGFHFYTLNL
EKVVSFVIERNGLIPEDDSAFEEIDGPVLAAHHRRTSSIADTHNHLIVDAPVRRDSMLLE
NSASAGFLAAEPAAAVTLAISEGEGTLGREATWDDFPNGRFGDARSPAFGDIDGYGPSLH
MSHSQAIGLWGYPVTPEDVSHLFIRYITGKLEAIPWSEQGLNDESRVIEEQLVGLNKKGW
WTVASQPAVNCAKSDDPIFGWGPEGGFVWQKSFVEFFCPGKDVDRVLEKLRAEGEKVSYY
AADAKGQFKTNVERENAMNAVTWGAFKAKEIITPTIIEEVNFKAWKEEAFTIWQEWSRVY
QPRTATSNFLAEVADTYWLVNVIHHEFPNQNALWELLGSL
>A0A850Q5Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Donghicola mangrovi|TrEMBL
MTAPRISFEFFPPQSLEASFRLWDTVQVLAPMGPRFISVTYGAGGTTRDLTHEAVTTLHK
TTGLPVAAHLTCVNATKEETLNIANAYAEAGINQIVALRGDPPKGSGGFKAHPEGFADSC
ELISALADTGKFTLRVGAYPEKHPEATDHKADVEWLKRKLDAGASEALTQFFFEAETFLR
FRDACADAGITAPIIPGILPIENWKGVKKFSAACGTSIPAWLDDAFDKALRDGRQDLLAT
ALCTELCDDLLREGVEDLHFYTLNRPELTRDVCHAIGVTPQVKLQNVA
>A0A5C8CZY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afipia sp|TrEMBL
MTISYPALHEASLAIGTPLFAGLPGDAEISFEFFPPKTDAMEEQLWRAFSALAPLGTRFV
SVTYGAGGSTRERTHHTVARIASETSIPAAAHLTCVGANKAEIAEVADQYWRAGVRHIVA
LRGDPPEMGQAFVPHPDGYASAADLVAGLRKQHDFEISVAAYPETHPEAVSARSDLDNLK
RKLDAGATRAISQFFFSADAFFRFRDAAAAAGIDAEIVPGILPVSNVAQTRKFAAMCGAA
IPPWMDRLFEGLDDHPAARQLVAATIAAELSRRLYAGGVRNFHFYTLNRAELSYAICHLL
GLRPGGAAQDKAA
>A0A4T3F9D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. P44RR-XXIV|TrEMBL
MSSKSENSQSGIRISFEFFPPKSEEAEQQLWNTVADLSDWEPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLATGVRRFVALRGDPPGGVGSAYQP
HPGGYANAADLVAALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRAAGIAIPVVPGIMPIQNLTQLKRFAGACGTSIPVALDQRFEGLDE
NTDERASVAADVAAEQIQDLMRRGIHEFHLYTMNRSPLVSAVLERLGLQRRVDARAGAAA
>A0A520W3C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Actinomarinales bacterium|TrEMBL
MTFGKDEVLSFEFFPPRNIQELNILEESCKLLAPYNPSFISFTDGAGGSKNRDIIEAVRI
LRKHLTTEVVAHITSCDKQEEDVDKMISTYLNEEIDSFLIIRGDCPTNEFLIDLDELEQD
LNGSFRHASDLIEYLNSKKINKIGFGAFPAGHPEDKEREEMLQTFKRKVNAGGTFSATQL
FFDFEEYTRLYEEIRQFDKTTPIYAGIMPLVSLRQAERFAEVCDIDLPEKLRRGFLECST
KEEERDFGLSYIADLCDSLIEYSADGLHFYTLNRAAAFIEITRVMKSFNLQKN
>A0A086WIQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. B183|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDASREELARIADDYWANGIQSIVALRGD
IPPGGGKPEMYASDLVKLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQV
>A0A0P7BM11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neonectria ditissima|TrEMBL
MHIRDMLADAERSGKPSFSFEYFPPKTAQGVQNLYERMDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVDRVNDALLKAYKAGCTNILALRGDPPRDQDT
WTATEGGFRYARDLVKHIRTTYGAHFDIGVAGYPEGADDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVGKVRDRGITIPILPGIMPIATYASFLRRAKHMQCKVPQEWMDAL
EPVKNDDVAVREVAKTLVADMCRKLLANGIFHLHFYTMNLAQATRMVLEELQWAPSAERP
LQQALPWKQSKGLGRREEDVRPVFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKSIQDIANLFVRYLHNEIDSLPWSEAPLTSEADEIRENLIS
LNKRGLLTVNSQPAVDGAKSSHPVHGWGPSNGYVYQKSYLELLVHPDVFEDMIGRIENHP
DLTFYAVTKDGELRSNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
GHCYDTNSPSRALIDQVMNEWYLVNIVNNDFHDNTTIFELLKNLEVKDLTTPASPKTVPA
TNGTAPAN
>G8R385|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Owenweeksia hongkongensis (strain DSM 17368 / CIP 108786 / JCM 12287 / NRRL B-23963 / UST20020801)|TrEMBL
MKVIDHINNAKETIFSFEILPPLKGQNIGEIYQTIDSLMEYKPPFVNVTYHREEVVYKQM
PGGLLEQKVIKKRPGTVGICAAIQNKYKIDAVPHILCGGFNREDTENALIDLNFLGIENV
LALRGDCIKGETYFKAEKDGHAFAADLVKQIYEMNEGVYLDEELQNRTPSNFCVGVAGYP
EKHFEAPSLNNDIAHMKAKIDAGAEYITTQLFFDNEKYFKYVEKCRAAGITVPIIPGIKP
IATKKHLSILPHFFHVDLPDDLVTAVEACKDNKEVRQVGIEWAINQCKELKKAGVPVLHF
YSMGKVDNIQSIAREVF
>A0A2E7HR41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MTKLSSIKSILEEKKKLFSVEFFPPKDEEGGQRMLETASLIQPHRPDFVSITYGAGGGTR
TTTMRYAKILREEHGFEVMPHLTCVGHTRDELLEILEDFAQAGFGNVMALRGDPPKGETK
FQTVPGGLSYGSDLVSLIRENFPDFGIGVGGYPEKHPEAPNKQIDLANLKTKVEAGADFI
TTQLFFDNQVYFDFVKQCEAAGMTIPILPGLLPVLSLGQVRRFCTMCEARLPTRLEKSLE
AAEQEKQPAVGTQWAGEQVQGLLKGGSPGFHLYALNKSASTLAILEGIGRK
>A0A412X2I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricimonas virosa|TrEMBL
MKVIDILNNTDKAVFSFELVPPLKGGDINKIYEAIEPLIALAPPFINITFHRDEVVYREY
PDGTIKKVTVTKRPGSVALAAAIMRRYNVDMVPHIVCGGATRHKIENELIDLNFLDIENV
MALRGDPIPGERFFTPEEGGHQYSCELVEQITRMNHGQYLDDTLTEAVPTNFCIGVAGYP
EKHYEAPNQACDIENLKKKVDAGANYIVTQMFFDNSKFFQFVDKCRAQGITVPIVPGLKP
ISTFKHLEMLPRTFSIDIPHELVKEIRSCKNNKEINQVGIEWCVVQSKELIAHGVPAVHY
YTMGKSENIQEIVKQVF
>R6YBA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:714|TrEMBL
MRVIDLIKSTPKTAFSFEILPPLKGTGIEKVYADIDMLREFDPKYINITTHRSEYVYQEL
GNGLFQRKRIRRRPGTVAVAAAIQNKYNITVVPHMLCSGFTQEDTEYMLLDLQFLGITDL
LVLRGDKAKHESSFIPEPGGHTHAIDLEKQIHEFNQGVFLDGSPIKAPVHTFSYGVACYP
EKHEEAPNMEQDLFWLKQKVEAGAEYAVTQMFFDNRHYFNFVDRAREAGITIPIIPGIKP
FGKLSQLSVIPKTFKIDLPQELASEALKCKNDEEARALGTEWCIQQCKELMSHNVPSIHF
YTVGAARAVHDVAQAIY
>A0A1W1GVK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas indicatrix|TrEMBL
MSAGVGRMEPLAQTFVNAFSLEVSAKAMPALRAEADRIARGTTISIPYLPSEDDAARLAA
ARRVRELGFEPMPHLSARRIGSRAALEHFIKHAVIDAGIERCFVIAGDLATPAGPFADST
SIIESGILERAGIKVVGVGGHPQGHPVMTSAERWRVLENKCQRIEERGMAPLVITQFAFD
ADIVLAWLNELRARGITHPVLVGVPGPASIARLVRYAAMCGVAASTSMLSRYGISIGRLL
GRAGPDVFVDRLAEGLTEAHGQVSPHLFPFGGIAPTIEWVEHYRMRAGDAHTTGSPVADE
PS
>A0A4T3FC07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. P44RR-XXIV|TrEMBL
MAHIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
SGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPHDFRPYRLAKKIEAGAQFVQSQYCYDVPMFRDYMNKVRDLGLDEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIAGVSGVH
VMAYRQEEYVAEMVHESGVLKGRQPWKHEANQTDALVAERLEHIRGGKEENQQEMAEAAA
HHPLHKTH
>A0A194AEZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoplanes formicivorans|TrEMBL
MKISELLEHNKPFVSLEFFPPRERVAWPGFFDVVRNLKTTQPLFVSVTYGAGGTRQTNTL
EIATRLKQEYDLEPLAHFTCVGASESRLRAFLDGLTDGGVENILALRGDPPRGEQHFNAS
DGRFSHAVDLVRFIREEYPHFCIGVAGYPETHPEASNSARDLDFLKEKLDAGADFVVTQL
FFDNALYFDFVSRARSIGITQPIIPGVLPVASLAGVKRMIGFCGATMPKAYLDDLELVQE
RYGDAAVRGLGLGYAQQQVRDLIEHDAPGVHLYTLNKAETCLEIVRGNQDLLDAGKKG
>A0A4R8DPB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dinghuibacter silviterrae|TrEMBL
MQVTQHLKEAKGTLISFEILPPLKGKTIQSIFDHLDPLMEFKPSFINVTYHRSEHVYKKR
ADGTFEKVEVRKRPGTVGICAAIMNRYRVDAIPHMICGGFSRQETEDALIDLAFLGIDNV
LVLRGDAAKNESSFEPEPNGHRYAIDLLRQVVHMNNGEYLEEDIRNGGRTGFCIGVAGYP
EKHFEAPNMDSDLSYLKAKVDAGADYITTQMFFDNQKYFDFVKRCREHDIHVPIIPGLKP
LTSKKQLNVLPRTFHVDIPNDLSEEITKCKTDAAVEQVGTEWLAQQSRELLAAGVPVLHY
YTLGKPQVIYDAVKSIL
>A0A381EAW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cardiobacterium valvarum|TrEMBL
MNIDKTDLQQLIHQYSIEIVPKTLRQIGDTRPWLAPGTEVYVPNLRSHKISDTIDACALL
QSQHMQAVPHLALRNIASEDELRHTLDRITALGIRRILVLAGGASEPLGPYGSVKDLMKT
GILQTYPFEHIGFAGHPEGSPDIPKAEQEAAEAQKQGYALTYPHDYYLTTQFCFQIAPIT
AWFDHLRARDITLPVHLGIPGVASTTSLIRHAQACGIGQSINFLWRNGRNIRRLMGLSTP
DKLLTDLAAYRKIRPENAIRKLHFYPLGGFETTINWLRAIEAGNITLTDEGFTANI
>A0A3D4H4P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MFEQKPIIDLLDSSVPTLSVEFFPPKSQDGVESLVDAASRIASRKPDFVSVTYGAGGSTR
DLSASVSERMKNDIDLQVMPHLTCVGSTKEELATIVDGFYQDGYRNIMALRGDPPKGQEA
FVRTEGGFSYASDLVAFIKSRHPDICLGIAGYPEKHPEAPSMDSDLDTLKVKADAGGSFI
TTQLFFDNAVFFQYMEKVQSRGIQIPIVPGIMPVLSLKQIKRITQLCQSSLPNSLESQLS
KVESDPEAVRRLGVEWAAAQIEDLLANGVPGIHIYALNKARSAIELIDAARR
>A0A7I7S241|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium arabiense|TrEMBL
MHSVTDQCPKRMHFGPCGGVRPDGQCEMRPGPCAFPAPVPWTGVVPETAPAAAPLILTDF
SCVPFDPEDVAATAAILGPSCDAVLVGEHQNRPDFPPTLMSRMLLDAGATPWITLSCRDR
NRIVLEQELRGLSLLGVPTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGMTAAV
PETPTAPPVAGRPARLVEKQRAGASLAVLNHVASPAMVADFMAAARAAGLVIPVVAAVAV
VTDERSAAVLAGLPGLALDDAIVDGILSAADPVEAGIEAACAEARALLSIDGVEGVNVSG
LASAASGRIGSETKAEVGRRIRTEVHGG
>A0A7X1I8H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bittarella massiliensis|TrEMBL
MDLCELFQQKKCVLSFEVFPPKKSSGVESIYRTLDELCALRPDFISVTFGAGGTGVKDNL
TVELAGAIRARGVEPLAHLTCINSDEETLLGLLDRLEEAGVRNILALRGDRVEGAEEGPY
RHANELMERIARRGGFNLVGACYPECHCEAPDALHDLQNLRRKQEAGATHLITQLFFDNR
CFYDFVEKARIAGVSLPIEAGIMPIVSKRQIERIVTLCGASIPPKFARMLSRFEGDPAAL
RDAGIAYATEQIIDLIGSGVEGIHIYTMNNPAVARRICENIATALDCVNGGGAA
>A0A8C2M8F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cricetulus griseus|TrEMBL
MVNEGSGSGSGSGSGSESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFSLEFFPP
RTAEGAVNLISRFDRMAAGGPLFLDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETVLH
VTCCQQRQEEITGHLHKAKQLGLKNIMALRGDPVGDHWETEEGGFSYATDLVKHIRSEFG
DYFDICVAGYPKGHPEAESFEEDLKHLKEKVSAGADFIITQLFFEANTFLSFVKACTEIG
ISCPILPGIFPIQGYTSLRQLVKLSKLEVPQNIKDVIEPIKDNDAAIRNYGIELAVSLCR
ELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDPRRPLPWAVSAHPKRREEYVRPIFW
ASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTS
EESVFKVFERYLSGEPNQHGYTVTCLPWNDDPLAAETSLMKEELLRVNRLGILTINSQPN
VNGKPSSDPVVGWGPSGGYVFQKAYLEFFTSREIVEALLQVLKKYELRVNFHIVDVQGKN
ITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRM
IIQYIHDNYFLVNLVDNEFLLDNCLWQVVEDTFELLNGHSVKGDAQAP
>A0A2M9MWD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. GM2FR|TrEMBL
MKPNLRQAWENQVLVGDGAMGTYLYQKGFPVGISYEELNLTSPEVIGNVHRQYVEAGAQV
IETNTFSANYDKLSKYGLEAKVGEINRAGVRIAREAAGDHGYVVGAVGSIRAGKRSNIST
SELKRYFEEQLSVLISEGVDGILLETFYDVDEIQLALAQARMLSDLPVICQFAVEDIART
LDGFTMPDAYRILSQEGADVIGFNCRTGPNGIMRALETLNGMMNLPASVYPNAGIADYVD
GEYRYGASPEYFGRTALEFADRGARIVGGCCGTTPEHIAEISSALSGYVPAPLPIVEEAE
VNRIVIHETAQEQFYERSGEPTIVDIVKERHTVIVELDPPRDLDITKFMKGAEALKKAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNEGIAFSGKPLKQKAKFVVGAAFNP
NVRHLDKAVARLEKKIASGADYVMTQPVYDPELMVRLREATAHLDIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAMGVKIGKELLDVATAHFNGIYLMTPFMFY
EMSVQLMEYVWEKSGRRLTPLFH
>A0A284VIV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedens nitroreducens|TrEMBL
MSFRKKLDSKKFIITAEISPPKGTDITGMQNDASMIKDVVDAINITDNQRAVMRMSSLAA
CSILSQNGYETIMHLTCRDKNRLALQSELLGASALGIHNVLVITGDHPAKGDHEGAKPVY
DFDSVQLLGLIKELNRGFDFSGNPLHGKPNLCAGAVAGTGLNELPFIKLEKKIKMGARFI
QTQAVFDTRSFSEFMDKIKNSETFREVKILAGIIPLRSEKNAAFLNKNMAGIKVPEDIIK
QMRGARNPVFKGMEIAAELIKELRSVCDGVHIMPVGNHEKTAGILEMAGIK
>A0A7K2WYZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID3212|TrEMBL
MAAETADRPPYPQPGPRALLSEGRRSFSFEFFPPKTEAGERTLWNAIRRIEPLAPTFVSV
TYGAGGSSRDRTVEVTKRIAAETTLTPVAHLTAVGHSVAELRHIIGQYADAGIRDVLALR
GDPPGDPRAEWVRHPEGFAQASELVTLIRDLGDFTVGVAAFPERHPRSADWDTDIRHFVA
KCRAGADYAITQMFFDVDDYLRLRDRLAAAGCTTPIIPEIMPATDVRQIRRFAELSDARF
PDHLAQRLEAARDNPADGHRIGVEHATAMAERLLAEGAPGLHYITLNRSTATLEIHQNLG
VSARDDREPATVPR
>A0A7X0VV19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella zeiphila|TrEMBL
MLTHKIANRQAGILTYGMTPPKQNYPADKIAEIAGKQVERLQDVGIDGLILYDVQDEADR
TEQDRPFPYLSTIDPSRYSKDYLSALQVPKIIYKVVGKQSEEELGEWIGTDADEDRFSVF
VGASSSKQAVTMKLPDAYRLGMALNGRLKIGGVVIPERHESKGDEHLRVAAKQQGGCSFF
VSQATYDVEASKNFLSDYYYYCRENGIPMAPILFNLAPCGSQKTLAFMKWLGISIPKWLE
NELIHCQDILDYSVRLSRMVFEELFEFGLEKGIPIGSSVESVSTRKVEIDASVGLLQEIK
RYMESRLSPRM
>A0A2E8U318|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetovibrio sp|TrEMBL
MVAEKSDLIDPQQNIIDFLADFTAETTPFSAAKVDDFREIXRPGTTVFITFLPGSDFEDT
IAIAARLKKEGLNPVPHLAARSIPDAAFLDEGLRRLRGEADIDEVLTIAGAVDQPLGAFS
DSMQVLETGLLDKHGIKRVGVAGHPEGSPDMPDEAIAAALTWKNDFANRSGADVYIVTQF
CFEAEPIIAWDKAIRAAGNALPIRIGVPGLATIKTLLNYAKACGIGNSMMFLKKQARNVA
KLMNVSAPDKLLVDLANYKATDPDCGLIGCHMYPLGGVKKTAKWTYAVVDGEFSMNPKGD
GFSLTMEI
>A0A1H3GLI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcaceae bacterium YAD3003|TrEMBL
MKVSQVYNTKRSLSFEIFPPKKDTELNNIDETLEVLAELKPDFISVTFGAGGSSNCNRTI
ELAKKIKYEYNIEPVVHLTCLHYDKHEIDEFAHVLKSEGIENILALRGDPNPNACAKDDF
KHSSDLISYLKDRNDFCFLGACYPECHPESPSTVSEIKSLKKKVDAGAEVLLSQLFFDND
IFYRFHEECEIAGIEIPVIPGVMPVINAAQIKRMVSLCNASFPKRFQRIISRYEDNREAL
FDAGMSYCLSQIIDLLVSDIKGIHLYTMNNPAVARRICEGIKNIV
>A0A524N2C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MARIPTLLRNGRTLSFEFFPPKTAGAHMTLGRTVAALEALHPDFVSITYGAGGSDRHRTG
DVVEWMRVETPWVPMPHLTCRGPSRADVATLLDTYQQIGIENILALGGDPPADGRDEAGD
YRYAIELLEDVVAAGCFAVGVAAHPEVHPRSSDRESDRRHLADKLSIADFALTQFFFEVE
HWVRLVDELSALGVDKPVLPGIMPISNKAQVKRMADMSGAALPTWLADRLDATDDLDDIR
AIGIEVATQLCSDLIDAGTPGLHLYALNRPDSVVAICENLGLAGS
>A0A353ZVU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp|TrEMBL
MFPTRIEIIPSTGIIDQVQALVPLTTTLTMTCLPHHGIERTMRTSVELSTLGYTVIPHLA
ARSINDRAELTRIMRECDVAGIGEVFVIGGDRKQPAGPYGSALPLLEDIAQYTGGRMRAG
VAGYPEGHPTVAALDLLDALQDKQHLATHVVTQMCFDAPKILDYAALLRREGVDLPVWAG
VAGSVPRTKLVALATQIGVGSSLKFLRRKGPLARKLLSGDRYSPHALVAGLESQPGIAGI
HLYSFNNLDAVPDEAGPASSPTALQPALIRGAAREH
>A0A2U4EUJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira hampsonii 30446|TrEMBL
MSNNVENFIKKLENKDEYTFTLEISPQAKYDLGYIEEKINKADISNYIDAFVVTDSPFAN
LKISSILAALQLQQRLNNNKPFITTQTMRDRNSIAIQNDLIGANYFDIRMVLAVTGDAIA
NGNQKQAKAVFEGNSQLLINIIKDLNKGKSLGEFAFKEPLKHIYPFCVINSYAKNNDTLK
LRLAKKANSGVKAIFTQPIYEAERLELFLKWIDELPLKEKPILVPGFFPVLSYKTAYFIY
YKLAGAYIPEIWLNKLKEASDKSPEEEKKVAVELSANLFNSMIKKHKKMHIMSMNNYDFV
VELLKNI
>A0A2T2T1X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QH_7_64_110|TrEMBL
MKVTEHFDQASEPLISYEIIPPKRGGSADQILRVVEELMPFDPPFIDVTSHSAEVEYKQQ
DDGTWQRCVKRKRPGTIGLCAAIEARFGIDTVPHLLCKGFTREETEDALIELNYLGVENV
LAIRGDDKGYEKSISGNRSRNEQAVDLVRQIQDMNQGTYLEDMMNAEPTDFCVGVGGYPE
THFEAPNLAWDIMRLKEKVDAGADYIVTQMFFDNEYFFNFVDKCREVGIDVPIVPGIKIL
KRKRHLRLLPKYFHTEIPEELAAEVDAADPDDVENIGVDWAIRQTRELMEAGVPCMHFYI
MSSADTVKKVVEPLHEMA
>A0A395JQ97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenicella xantha|TrEMBL
MSKSPELSFEFFPPRTDKGVATLNQVHAELARFEPEFFSVTFGAGGSTQDGTFDAVKSML
AAGSDAAPHISCVGSSKQNIKQMVDGYMALGVKRLVVLRGDLPSGMVERGDFAYANELVE
YIRKEYGDSLHLEVAAYPDFHPESRSPQKDIENFKRKVDAGANSALTQYFYNADSYFSYV
DEAQRMGVDVPIIPGIMPITNYTMLVRFSDNCGAELPRWIRARLEQYQDDEASLKAFGLD
VVTHLCFDLLDNGVQGLHFYALNKIEPVKEICTRVGFQLASS
>E6JA49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia cinnamea P4|TrEMBL
MTQLPDPDPTDGGRHPSIVERIATSTTPRVPFSVEFYPPRDEAAEERLWRAASVFSELGA
AFVSVTYGAGGSTRDRTVRVVEGIVRETDLVPIAHLTAVGHTVDELADMIRMYGEVGVSN
ILALRGDPPGDPLGEWTAHPEGLRYAEELVRLIHEVGDFHVGVASFPEGHYRARDLDHDT
EVLVGKLRAGAEYSITQMFWDVEHYLRLRDRAVAADPEQGAKPIIPGLMPVTSLRQVKRM
VELSGCALPDDLAERLRTAAGNGPEENREAVREVGIDLTTRMCERLIAEGVPCLHFNTLN
FSRATREVLTNLSMAPAPGVAASRI
>A0A0D6EDJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. R57-5|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIYVRDELAARNPRFFSVTYGAGGSTQARTRQVVR
EVSESGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKIVDNLTD
>A0A399RHI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Henriciella mobilis|TrEMBL
MSDLSVAARQAGKTPSVSFEFFPPKNESMTEKLWECVRRLEPMSPHFVSVTYGAGGSTRT
RTHETVSRIARETSLTPAAHLTCVGAPREEVLQTAEDYYEAGVRHIVALRGDAPQDEDFK
QPEGRYTSVVDLVSDLRAHRPDLGKVFEVSVACYPEPHPDSRGWEADLAHLKRKQDAGAD
RAITQFFFDPDVYFDFVDKARGAGITMPIVPGIMLQSNFKGLKNFAKMCGASLPDWLHKL
YEGLDDDATTRDLITANVAAELCHKLADGGVNQFHFYTLNKADLALSTCHLLGLKPAHAE
AA
>A0A4V3GX43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium congolense|TrEMBL
MKIKNIFEEKEVVFSLEVFPPRPDVPIENIYQTLEELKDIDPDYISVTYGAGGGLRKNRT
CELSSIIKEKYDVEALAHLTCINSDQETLNKILARLESKNIENILALRGDKQVDGEAIGD
YNYAYQLVEHINKNNDFGVAAACYPEGHLETDSLEQDLEYLKQKVDFGVDYLISQMFFDN
SLFYKFRNKAEKKGINVPIEAGIMPVINKKQVGRIIELSDAYFPKKFQKILDKYEDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKAD
>A0A8B7PJ27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyalella azteca|TrEMBL
MSERQAPISFEFFPPNTPVGSEKLKTVVKDLSVVNPEFFSVTYGAGGATREKTLATVQDI
ATLGYEAAPHLSCVGSTREGIAEILQTYRAQGIHRLVALRGDLPSGTAVAGEFRYASELV
RFIRETQGEDWHIEVAAYPEYHPQQRYAARDLQHFAEKMKAGANAAITQFFFNPDAYFHF
VDEVRKLGVTAPIVPGIMPIHNYARIAQFAQRDGIEIPRWVALKMEGFMDDAASVRAFGL
DVVTRLCERLLADGAPGIHFYTLNQSALSLEICNRLGR
>A0A6M6JJ22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia broussonetiae|TrEMBL
MRPATTGAEPVAVRAALAAALREASYEVLPLRGAEDRVLGSVPREVPLTVTTTEARGLEP
TLDLAVRLTAAGYRAAPHLAARMFRDAAHLHDVLRRLREARVDGVFVIGGDGPAPAGPFP
DALSLLEALDHEGGPFGSVGIGGYPEGHGRIEEALIERALVAKAPHATHVVTQLCFDAAA
TVRWARRIREDGVALPVRVGVPGPVARTKLVRIAAGLGLGQSARFLAKQQNLVGRFLLPG
GYRPDRLVRRLAPTLAQPDGVLAGLHVYTFNELASTEAWRQRWLARLAEAA
>A0A8H4SLK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium sp. str. #12|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEAAENGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNTDVDQLIDHLKEKVDAGSSF
VVTQMFYDAENFIEWLKKCRAKGITIPIIPGIMPIQTYASFIRRSSWTKVKVPPQWMEAL
EPVKNDDSAVRDIGKTLIADMCRKLVAAGIKHLHFYTMNLAQATQLVLKELDLSPSDESP
IQRALPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISDIFVNFLTGKLDRLPWSDSPITTEAHDIQEDLLN
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLLDELITRIEKND
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCHDAASPSRKLIQHVMDDWHLVNIVDNDFHRSNAVFELFNGLEIKDLNVEVAGKPLTNG
HAEQNGVAAN
>A0A4Z0GPK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporolactobacillus shoreae|TrEMBL
MKTPILDEMKKRILIGDGAMGTLLYSYGIDRCFEELNVSHASEVLHVHQAYIGAGADVVQ
TNTYGANAIKLARYGLEHEVGRFNKAAVQLAKKAAKPETYVFGTIGGIRGFQKQSVQTEE
IRRSFREQADVLLDGGVDGLLLETYYDFSELKEVLKLAREATDLPIVAHVSMQEPGVLIN
GMSLAEALRELESLGADIVGTNCRLGPFHMIQALRGIPLPKRAFLSAYPNGSLPDYRDGK
LYYETEPGYFKKYAVDFRNEGIRLLGGCCGTTPVHIEAFRQGLSELEPIREKSVSKRVST
IIISDNHPETPLFEKAKSGRSVFVEFDTPRHLNTSGFFRGVRALQDAGADAITMADNSLA
SPRISNAAIGRLIKEEFTVPPLVHLTCRDRNLIGLQSHLMGLDVLGLHDVLIVTGDPTKI
GDFPGATSVYDVSSMELIRLVKQFNHGISYSGKSLRHPTHFRVAAAFNPNVRNLDRAVQR
LKRKIECGADYFISQPVFDRQQIIETSKALRGISAPVYIGIMPLTSATNAEFLHNEVPGI
RLPDDVRERMAAARTPEEARRTSLEIAKELIDTSMEYFRGIYLITPMGRFTVTVELLKYI
KEKERLLLAAPGHQAGEIV
>A0A7C0TWN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidilobales archaeon|TrEMBL
MGFKCPKRMLNGPCSSYRDNLCELGNVACPWIGAYKVLSKYGKLNEFFKFRLDPDFVVRD
YYPVTRRSQTLVNKLLSGKLMVFYEVYIPKYHRVLKHLEELKELAKYVDFYVIPDSPFGL
PTPHVLTVATAIKLLIGNSVITEISCRNKTKEEFIKLILTSLSLGIEDFIITTGDLPLGE
GGEYYFELDSCRATYLTRLIADLGIDHKGRYVSLGGFNVSIGVVTNPNSKYLDLEVGKTL
RKLRCGANVVFLQLTYDFKLITDLVKALRNEVNNLPIVPLFVPLKKVSDVNMVKHLGIRI
GKNVREKALDYLRKGKALELNIELLRNLIEVMDTTGLSSIYISTYGDITLAKELIKVVKG
VGKGLTVLRG
>A0A1F6QR32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Melainabacteria bacterium RIFCSPLOWO2_12_FULL_35_11|TrEMBL
MTLAEALNQKKFIITCELAPPKGTDVSNLSKMAILLKNLVDAVNLTDGQGGNMRMCPLTA
AHFLLKEDVDVIWQLTCRDRNRIAIQADCLGAGALGIKNVLPMKGDDPKSGDHPDAKAVF
DLETIGLIKVLKKLNDGFDMTGNGLKGKTNFLIGCTAHPGIPDLLKQQELIKEKFSLGVN
FVQTQICYEIDQIKKFIELLGEFAKKTIIGITPLKSLKMASFMNEKVFGVTVPEKTMKRI
EGAKEQRQEGLIIAREIVNELKNTGIGGIHVMAVGQEQALPEVVSFLTN
>A0A1Q9GF26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium proteolyticum|TrEMBL
MESDIEPRLFQLLAEASLEATPKQVLKLHTVPDWLSAGTWVYVPFLPKGRFEETFEACER
LLLWGMVPIPHIPARAVPSEACLHRWLSSLTHIGVYNILLIAGEKNPPAGPFANTLALLA
SGALAKHPLRGIGVAGHPEGHPHATSHELTNALSFKREYAEANQLNMWVVTQFSFDADIF
IQWLECYQELLGSLPVYLGMPGPTQLKNLFFYAAQCGVVESVAALRRNLKATQLLKPWTP
DLLVQEMARYQSINPDTPFQGIHLYPFGGLKQSARWLRRAR
>A0A0A6DHR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas chlororaphis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFIRKARAGADSAITQYFFNADSYFY
FVDRLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A522GWK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp|TrEMBL
MPPISFEFFPPKTDEQRVQLDRAAQLLKAYQPDYASVTFGAGGSTLSYTGDTVARLHQQH
GFHVAPHLSCVGGTRAELAELLDTYRNAGYRRIVALRGDLPSGMASPGDFRYAAELVRFI
RQHSGDHFHIEVAAYPETHPQADDALRDLQHFKAKVDAGANGAITQYFFNPDAYFRFVDD
AHKLGVNVPIVPGIMPIANYSQLKRFSDMCGAEIPRWIAKRMLAHGDDAAAVRALGAEVV
AQLCRRLLAGGAPGLHFYTLNRARATQAVLQQLV
>A0A1A3SB46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. 1165178.9|TrEMBL
MPADSGCPKRMEFGPCGGVRPDGQCEMRPGPCVFDDVVPWSGLRPIPRLASAPRVLTDFS
ATPFNPDDIAATAAILAPGCDAVLVGEHQNKPDFPPTLMASLLLDVGVTPWITLSCRDRN
RVVLEQELRGLLSIDVETVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGIAAAAP
ETPTAPPVHRRPARLVEKQRAGASLAVLNHVPFPDMVADFMTTARSAGLTIPVIAAVAVF
TDSISAAVLEGLPGLELDPAVTQLVLSAPDPVAAGIEAAVNEARALLSIEGIEGVNVSGL
ASASGPRVGAEIKAEVGRLIRAETP
>A0A521VUI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthobacteraceae bacterium|TrEMBL
MPATPGPATFKDKLERGDFVFTGEVTPPLSSDPEELLALARPLRGLADAVNVTDAASARA
QMGALAAAALIRSEGLEPILQLTCRDRNRIALQGDLIGAAALGVRNLLVLHGDTPAAGDQ
PDARAVFDLSSNALAETARLIRDEHRLPNGRKVGGRAAFFIGGADTPVEPGPDWSPQRLA
AKRAAGIAFIQTQFCMDAGLLRRYMARLHAEGLIPGLRYLIGIAPLYSAKSARWMREKLP
GTVIPDALVARIEKAADPPAEGQRICLELIAELATIPGVAGVHLMAPRNEPTIAAVIAAA
RALVSRAATF
>A0A5N1JC12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Larkinella sp. MA1|TrEMBL
MAKVSDHIRQANGKTIFSIEVIPPIKGDNLKNLLDNIEPLMAFNPPFIDVTYHREEYIER
VEPDGTVKKIITRKRPGTVGICSAIMHKFGVDPVPHVLCGGFTKEETEDFLIDLHYLGID
NVLVLRGDPAKPFDTFKPKTNGYAYASELVTQVANMNRGVYLHEGSHAMTPSNFCIGVAA
YPEKHFEAIDHDTDFRYLKLKVDKGADYIVTQMFFDNQKYFDFVRRCREAGITVPIIPGL
KPLSTRKQLQVLPRLFHLEMPADLVKAVEACEDDKQARQVGIDWCIQQCRELTKAGVPGL
HFYTMGKSDNIVKIAREIF
>A0A1C4CDI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella bombicola|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISANVPPKDDF
RYASELVTFIKENGDFNVIGACYPEGHLEASTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKAHDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVATLLAVPKTKQ
>A0A416D594|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium AF36-3BH|TrEMBL
MFIRDIFAQKKPVLSFEVFPPKKDSGLDNVISAVDELSKMPIDYMSVTYGAGGSNSKNTA
YIASHLKNNLSIPSLAHLTCVANSKGDIKVKLQEYKDLGIENILALRGDKPKDYDGEIFP
GYHYANELVEAIKDFGDFCVGGACYPECHPDSSSLDADIENLKVKVDAGVDFLVTQMFFD
NNEFYKFRDKLAKKGINKPITAGIMPLTNAGQIQRMAILSGGASMPSKFLRMISKYQDNP
EALKQAGIAYAVDQIIDLLSNDIDGIHLYTMNKPETAQKIVNVINNLFV
>A0A5C5V744|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Posidoniimonas corsicana|TrEMBL
MTIAAAYGPDRVALSFELFPPKTDQGDAALLKHVARLMEFRPSFVTCTYGAGGSTQDKTL
QIVSRVHQDFDVPVATHLTCVGSTADQLRSYLSDAVAAGVQNVVALRGDPPKGEEQFRQT
AGGFAYANELVAMIRGEFPTLGIAVAGYPEVHQEAPSREADLENLKRKVDAGADAVITQL
FYDNQDFFRFRDDCRRAGIEAPIVPGLLPITNTAQIKRITALCGARLPAELVDRLEAAGE
DPDSQFEAGVEIATRQTVELLDQGVPGIHYYVLNKSEAASRVLQSVNLRG
>A0A847PKB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
LGAYALGVHNILALTGDHPKMGDHPNASAVFDTDSIGLIKIIQELNQGTFAGNKTANYNT
GFFAGVAVNPDFKELNKELPRLEKKVAAGAHFIQTQPIFSRRVIEDFLNTTQHITIPKII
GIMPLRSIKMINYIEKNLQHIFIPDSIKYRMFDSGIEEGITIAQELINDFLTIKEVAGIH
IYPMNRLSIVPQLIDYRNE
>A0A6A8N3V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNQQNGLEPRKSLLPRPTISFEFFPPKDEQGESNLHLTIEELKRFNPDFVTLTYGAGGST
RDRTVRIAAEIIARHQIPTMAHLTCVGSTRKELTEILHEYSKVGVKDLLALRGDPVGGPT
SEWISTPGGFDYADQLVDLATKVGGFNVGVAAFPDVHPASHGNFQ
>A0A7U0DGP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium amycolatum|TrEMBL
MPLSPGRQVTIRQALSMPSAGSIPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFASVTY
GAGGSSRDRTLRIAQRVSKQPLTTLVHLTLVEHTVDELREILRSYLSAGLTNLLVLRGDP
PGDPLGPWMETEGGLHYASELIELIKAESEFEKFEIGIASFPEGHYRSPDLDHDTQYTLA
KLRAGAEYSITQMFFDIEHYLRLRDRLAEADPVHGVKPIIPGLMPITSLRSVRRQVELSG
AQLPSDLEERLIKAADGDEQANKDEIRKIGIEFSTNMAERLIAEGVPGLHFMTMNFARAS
QEVLHNLGMAPAWGTGQDMLRGGF
>A0A537VXK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPGPRRRSLRIPARTARTPCERIVLRLRRSGPGVGSSPPQGALPGPGITPNVRRVPRPKG
PNHVRMAATGRPEGATVVGRWTRHPGAVGRLERTGDGKLRREGWDTARMDAAVFRSLLAE
APLLADGGMGTSLIARGVPVDACMEELNVRAPTRVAEIHASFVGAGARLVLTNTFGANRY
RLERHGLADRFAELCVAGVALARDAGAPIVAGSMGPLGIRLQPYGRVHPEDAFAAYREQA
AALADAGVDLLIVETQSDLRELEQGVLGARDAAPDVALIASATFTRDDRTLLGSPPEEVA
QTVVALGVDALGVNCGEGPAQVLRIVRAMRRTAAGAGVPIVARPNAGGPAEVGGRFVYPA
TPEYFGEIARALLDEGVAVIGGCCGTGPAHTTAIGTALHDRAPHVRIEFPEADHGERILD
VVTVAPPTKLEAKLATGHFVVTVEMEPPRSFNAARLVAAAETLRDAGADAIDVADSPMAK
MRMSAWAACRLIHEQADIETVLHFPTRGRNLLRLQGDLLGAYALGIRNLFVCVGDPVTIG
EYPHGSNNVDVTATGLLSMITHAFNAGVDRSGTSIGAPTSFFAGAAVAPSAPDLEREARL
LARKAEAGARFVLTQPFYSIEPLLALRETYEKVADEPLTVPIVAGVLPLMTSRHAEFLHN
EVPGIEIPEAS
>A0A7W0P4C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
HEAGAEPTLQLVCRDRNRLAITADLLGGWALGARNILVLGGDPMDVGDHPDAKPVFDLGP
NQVVQLARRIREEGITGAGAEIADPPRYLIGIADVPLSDPYDPAKLEAKLDAGGDVVWTQ
IAYDVDRLAEWADLVRPRGIFERAKVLVGLVPLRSLKNARFMDGLFGVHVPQAAFDVLET
AGSEAERAGLEFTIDVARRIREIDGISGLHLMGIGRDDLVRAVVEEAGLFPRPTSI
>Q9KCE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)|TrEMBL
MTNLVEALKTNILVGDGAMGTLLYEQGIDRCFEELNVTDPEKIVAAHVAYVEAGADVIQT
NTYAANRMKLAKYQLDDQVLEINRAAVRLARKAAKQETFVLGTIGGIRSVQFEEVEIQEV
QDVFLEQMKALVSEGVDGLLLETFYDLEEAKLAVSLARSLTDLPVIAHLSIAEIGVLQGG
KLLEEAFAELEGLGADLVGINCRMGPYQMLRSLETVQLLDRAYYSAYPNASLPDYRDGRL
YYHSNPEYFYEMGKRFVQQGVRLLGGCCGTTPEHVRAFAKVVKGLKPVVSKPVRLEIKET
LSSTGQKTAREPLAEKVKKQPSIIVELDPPKNLAIDRFVEGAAALKNAGVDAVTMADNSL
ASPRVDNLALGAIIQQQVGARPLVHVTCRDRNLIGLQSHLMGLHALGMTDLLAITGDPTK
VGDFPGATSVYDVTSFQLISLIKQLNEGISFSGKELGQKANFSVGAAFNPNVRHLERAVQ
RMEKKIEAGADYFMTQPIYNEKQIEDIYEATKHIEKPIYIGIMPLINGRNAEFLHNEVPG
IKLTDQIRERMARAGEDRQKGEREGLAIAKSLLDVATHYFNGIYLITPFLRYGMTVDLTH
YVKETHHQIRQPERSVQK
>A0A7K0RK06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSEDSVRGRSSRGFVTRTPSIVDRLRTEPEARIPFSVEFSPPRDEAAEARLWQAVREFEQ
LQPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSVAELRSMVGSYADRG
ITNILVLRGDPPGDPLGEWEKHPEGVEYAEELVRMVRELGDFHVGVASFPEGHHRADDLE
QDTRCLVGKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSV
RRMLELSGTTLPSHLDEKFTRAAGSGAEEDKAAVREVGIELATNIGERLIAEGAPGLHFI
TLNFARATREVLSNLGLAAARV
>A0A7V4MY19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKIVEVFDSRLSFSFEVFPPKSEEGMERLKEALKHYYRFQPDFISCTYAAGGTNADRNLE
VCRTIKTDGLTEVLTHFTCIGFTRDRIDTQLERYLSLGIENILAMRGDLPAGWDGTRGDF
SHADGLIRHVRQRFPQFCIAAACYPEKHLLAPSLAADIAFLRSKQDNGADFLISQLCHDV
GAFERFLYLIREAAVSLPMVVGILPVLEKDALIRMTLSNGCSIPAELAAIIGKYGDDPQD
FKKAGIEYTIQQIHRYIAAGVEGIHLYTLNKWEEVEEIVAGSGIREAVTRTFDLVAQVG
>A0A7K3K7Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola sartorii|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYDTIDTLREFDPLYINITTHRSEYVYREL
GDGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEENGYAHALELEEQINAFNEGKFIDGTPIQAPLSPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVETGASYVVTQMFYDNQKYIEFVERARKEGIHVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVMEAMKCKDDKEARALGIEWCVNQCRELIEYGVPGIHF
YTVGAVENVKEVARAVY
>A0A6I3CWU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRLEKRMYSFEFFPPKDVAGEDRLWQALSSLATLHPDFVAVTYGAGGGTRDRTIRITSEI
TARTSIPTVAHLTCVGSTRDELIEILHRYTESGIKSILALRGDPVGGPRAPWTPVDGGLT
HADELITLAREQGDFTIGVAAFPDGHPNSEGNFDKDIDVLLRKESLGASFATTQFFFEVD
KWKRLVDALAKRGSTMPIIAGVLPVTNVKLLTKMAELGGTPIPDSIASRFAAVEDNPEDV
RKLGVEIALNLCNDLIDAGVPGIHFYTMNSSTATSEIFESLQDRR
>A0A538AUC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MLKRSEFADLVAEQPLLADGGTGTTLVAGGVRPDACFDALNVAARDLVREVHESFVEAGA
QVIETNTFGANRYKLAAHDFAFRVHEINVAGVARAREAGARYVAGSVGPLGVRLAPYGRV
PKDEAQEAFAEQIRGLADGGADLLILETHSDVAELEQAVLAARAVTDLPVIASLTFTRDD
RTLLGESPEAAAARLAGLEVDMLGVNCSEGPEQVLRLITVMKPHAGGIPLVAQPNAGGPQ
RLGGRIMFSATPEYFGEYATAFVAAGVRLVGGCCGTQPAHIRAMASALAAPARPLDIEVE
EQPGEPADVRIPSERPTGLATKLASRALTIAVEMEPPRGFSAARLVAGADTLRAAGADVI
NVSDMPTARMRMSAWAACHLVQQEAGIETVLHFPTRGRNLLRVQGDLLAAYALGIRNIFA
VMGDSTSIGDFPEATDLSDVTPSGLIALVKGSLNAGLDRAGSSIGDPTSFVVACALNVTA
SDLEREARVLKRKIDAGADYAITQAIFDAERLDRFRALYEERYGPLELPILGGVLPIASR
RHAEFLHNEVPGIDIPDAIRKRVGKAADERAEGLAVAVNLCEELRARVAGLYLIPPFRRY
DHAAELIELVRS
>A0A6I3WJQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAIFRSHDRRPDAGSAALAPVIVDRVQHAHLELIPTPKAHLQFPALPPACTVSVTCSPAK
DIQATLDMAAQLLDLGHTVIPHLAARMVEGPDHVAGIASWFNDHGVSDVFVIGGDAPEPR
GPYLDAAALIAALLDSNARLTNIGFGGYPDGHATIPLPALAEAITAKQQLLDSAGISGWV
STQMCFDTKAVTRWISQNRAAGMHLPIHLGIPGVIDTTKLLTMGAKLGIGASLRYLRKNR
AVVSKLATPGGYDPMDMLAPMARDIETLDIAALHIFTFNQVTNTAEWRRAVLDGAGPTES
NLNTGSNNDSGTSTTAGAASLTRG
>A0A537ZW46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDEILGGTEPVFSIEFFPPKTPEKVEDLFETVEALKPLAPNYVSVTYGAGGATRDGTV
EIANRIKQEYGLEAMAHLSCVGETQEGLVEILDRFHEAGIENVLALRGDPPRGEAAFRPP
EGGLSCAAELAGFISERYDFTIGGACFPEVHPEAPDLEADLAYLKTKVDAGASFLITQLF
FDNSLYFDFVSAAREAGIGVPIIPGVIPITSFDQIVRFCDRCDASIPEELARAMHALGGD
TEAEALLGVAYAARQCDELLAGGAPGIHFYALNRAPGTRAVLSALRASRPWERAQAPPPS
PEFAV
>A0A1C3E6Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctopirus hydrillae|TrEMBL
MTVLTTPNALPSTNLRSLYASGQFALSIEIFPPKTAEGDAALRHALQEFSTYNPAFVSCT
YGAGGSTRSRTLDWCREIIDRVGVAPTAHFTCVGSNSDELIDWLGQAWQLGVRNIMALRG
DVPQGETEFKAVKGGFSHARQLVELIRKEFPEMGIGVAGYPEKHPEAASLEADIGFLKEK
ITAGGHAVFTQLFYDNDTFYRYWEMCLKQGIDAPIIPGVMPITEYSRVKRIVEISGTKVP
AELLKQLEAAHLRDDKAAQLEIGIEYSVQQCQDLIDHGVPGLHFYVLNKAHATSQILQSL
GLKNSEITTS
>A0A1R4GJK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrococcus casei LMG 22410|TrEMBL
MTLPYSFELFPPRTPNGFDRIDRTVEMFAKLDPAFVSVTFGAGGSDSRHSLGVLQRLLDA
GVPPMAHLTCVGLDVEQASRLVRSFLDAGITRFLALRGDLPHDAGDRVTDLRSAAELVQL
IDRVDTEREPYQSLLLPGLRRSEIRDRQSKTEISVAAFPNGHPGAGVHRSDVAALLAKQS
AGATMAITQLFFDPFDYLEFVDLARAKGVTIPIVPGIVIPTSLRRLERSAELSGERLPTE
LARRLDGASDDDARRIGVDTAVALIDELRDHDVPGIHLYTFNDHRPAFDVLDHIGLTSVG
ASPA
>A0A387BDL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus allomyrinae|TrEMBL
MVNKPKKMLSFEVFPPNTEVGTSKLFKTLDDLKELSPDFISVTCSNNNRTDIGRTTIRVA
DYVNNTLNIPAVAHLSAAYLDKNQVKEILEQLKAKGIYQILALRGDITTLPAKNDFHFAS
DLVRFIKAYDETFEISGACYPDIHPESLNRITDFHYLKEKVDSGCDKLITQLFFDNNTFY
DFQERCAIAGIEVPILAGIMPIVNRNQAIRLLKTCNTPLPKKFVRILEKYEHNPIALKDA
GIAFAIDQIIDLTTEDVDGIHLYTMNNAETAKSIHHATSSLFY
>A0A2N5JZ81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARIADLLAVGPTFSFEFFPPRTEEAERALEQALAELEPLRPSFVSVTYGAGGSTRERTH
DIVARINRDTSMTAMAHLTCAGHTRAELTEIITGYRAEGLENILALAGDPPSTTTGEQPP
PADFRYATELVELVRSLGHFCVGVAAHPELHPRSAGDRAADRDRLAAKLAAADFAITQFF
FTTEPYLRMVEELADRDVTAPVIPGVMPVTNVSQVERFAQLSGSAFPAELAERLHAVADR
PDDVRRIGVEVATKLCQDLLDAGVPGLHFYTLNRSTATREIYANLGLGADGAGLSARNHA
>A0A4R1FBS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia alba|TrEMBL
MVQSLRTHSGNGVPFSVEFNPPRDEAGEARLWRAVREFERLHPAFVSMTYGAGGSTRDRT
VRITGELAQETTLLPVAHLTAVGHSIAELRSLIGSYADSGICNVLVLRGDPPGDPLGEWA
KHPGGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLDHDTRHLAAKLRAGAEYSITQ
MFFDVEHYLRLRDRVIAMDPIEGAKPIIPELMPITSLRTVARAEELSGRPVPADVVARLT
RAAGTGPEEDRAAVRAEGIQIATEMAQRLTDEGAPCLHFITLNFAKATSEVLTNLGYGVS
AAPLSA
>A0A0M9CP60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. XY332|TrEMBL
MSARPTPYPERPVPAPVTGGGLAELLRRVRYEVLPAKATEDKVLAHVPADVPVTVTASPA
KGLGPTLDLATRLAGHGYRVVPHIPARQVSDAAHLADIVDRLVAAGIEDVFVPAGDADPP
AGAYDAALPVLRRLGELGSPFAHVGITGYPESHPLIADDVTVQAMSDKQPHATYIVSNLC
FDPATLRQWLARVRRRHVVLPVHVGIAGPVERAKLLSMATKIGVGESAKFLTRHPSWFLR
FAAPGGYSPERLLRRSAPALGSPEAAVAGLHLFTFNQIAETERWRRAMLERIGG
>A0A537ZJF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSETPGHLGRILRSGRFCVTAEVVPPRSADPAAVVAQAKELVGYADAVNVTDNPASAAHM
APLAGVAVVADAGIEPILQLTCRDRNRLALTADLLGGWALGARAVLCLSGDPAARGDHPD
AKEVYDLTVLDLVGLAASLRDEGRLLSGATIEGPPRYLIGVADLPLAAGYDPTRLEAKIS
AGADFVQTQIVYDVEAFTAWADGARSRGVFDRVAVIAGVAPLRNARQARLVGSLPGVSVP
ADVLRALEEAGADAETEGTRLAILIVNGLREIPGLAGVHLMGLGQESAVRRVVEGAGLLP
RPVAAP
>A0A3C1P0G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSAPLDLGEVLSAGRRSFSFELFPPKTDEGERVLWQTVREIEALKPTFVSVTYGAGGSTQ
DRTVRLTGEIARDTTLTPVAHLTCVGASREEIRGVIGQYAAEGVRTVLALRGDPPTGLGS
TWQAHPGGLEHAVELVELVRSLGSFSVGVAAFPEGHPESPDLDHDARVLALKQRAGADFA
ITQLFFRVEDYVRMVDLATAAGCTMPIIPGIMPVTNVAQIERFADLSGAVFPVALAERFH
AVADDSEAVIELGVEVAAQMCQQLLDAGAPGLHFYTLNRSRSTIEVYEALGLGALTG
>A0A538GJB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSDRFEKRLERGPPVVTDGGMGVLVSSAVAGLRCPEEANIRAPESVVTLHTSFIAAGAEL
IETNTFGANRHKLRSQFLDNEVAAINEAGVKLAREAREISGRDVFVAGSIGPLGELGGLA
ADERGPVFAEQAALLEGRGVNLFMVETFFDLDELTTAIEAVQGVSGLPIVAMLTFDEDAE
TFGGVSARDAVERLTQYELAAVGANHGAGLHAALAALEAMGDGRPLAALPNVGLASLSGG
RVIYPHATPEYFAEFAAQARALGARVIGGCCGTTPTEIAAIARAVEEERQPTVPFAAAER
ELVVAAHERPEETELARRLHAGEWVTCVELDPPKGGSYESMLAVTRTLNGSGAVGFVDIN
DNPMARARANALMAAIAIERSCAIETIPHVTPRDTSVMGLQSQLLAAHAEGVRNVLAVTG
DPPHVGDYPGSRGVYEVDSIGLSQVVSRLNAGEDFNGKAIDAPTSFFLGVAVNPSADDLE
TELDRFHQKVEAGARFAMTQALFDLAYLDRFEQLLGGWPIPILVGIFMVRTHQLAVRLHN
EVPGIVVPEDVQNRLRDAGPRAAEVGLELARELYAEAREKAGGVYVIPPFKQPEAALELL
GS
>A0A3A4PDT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKSGSNLERVLEAGHFAVTAEIGPPKSGSARVIEAHGEEIGHAADAFNVTDHQTGVVRLC
SLASCAILRRMGLDAVMQTLCRDANRIRLQGDILGAVALDIKNILCLSGDHVKFGNHPEA
KGVFDIDSVQLIQTVRMMRDEHKFICGEEVAGDVPLFIGAVENPYADPFEFRTARLAKKI
AAGADFIQTQAVYDVPKFSRWMEEICDAGIDEKTHILAGIIPVKSVGMARYMKKFVSGVE
VPDEMIKRLEDAKDVKEEGIDFILEIIEQVKQIQGVHGIHVQAVGWEEIVPEIMERAGLL
PRPVL
>A0A538GD08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSRFEERLAQPTPIVADGGMGALLSSAVAGLRCPEEANLRATESVLEVHLGYIRAGAELI
ETNTFGANRAKLARQFLADELEAINAAAVRIAREAREVAGRDVFIAGSVGPLGDYELAGH
DPVHLYAEQAQILEGRGVDLFMVETFYDLDELETAIGAVRSVSSLPVVALLTFDAGGETL
AGVKAEDAAARLQPLGLAAYGANHGAGPAAALTALAQMAGDGAVLAALPNVGLASMSGQR
IVFPHATPAYFAEFAAQARALGARVIGGCCGTTPAQVAAIRDAVDADRRPAGSFLLQERE
QVVPFEPATGETQLSRLLREGEFALSVQVDPPLGANPEALIETARAVRESGRAQFLDVND
NPRARARMSGIMASVAIERFTGVETIPHLTPRDTTIAGLESLLLGAHAEGVRNILAVTGD
PPEAGDYPGTHAVYDVDSIGLVELIAKLNAGEDWHGRAIDAPTTFFPGAAVNPTADDLGL
EADRFHRKVAAGARFAMTQILFDLEALEAFRERIGGWP
>A0A537XIV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPLTALTSAEISLPGTPDALRVRERIAALADTVDVVGLTDNHAGQPRMSPLAAVALAREQ
GVETIVHVSCRDRNRLALQSQVVGAAALGTEGVLCLYGDQVEGVPHVQDLTTTSLIAEVK
RWAAPHELAIGAVVNPFAEDLNREIGLLERKCAAGAEFVQSQMIFDLERLREFLDRTKDL
LADIRFYASVALLRNQRMADRAQRLPGCLLPEAIYRQISTGGGLELATELATELATISGV
DALHIYPLGAEVATREVAATFRGARGVAAHRR
>A0A1V2CA04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium amycolatum|TrEMBL
MSSTMPLSPGRQVTIRQALSMPSAGSIPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFA
SVTYGAGGSSRDRTLRIAQRVSKQPLTTLVHLTLVEHTVDELREILRSYLSAGLTNLLVL
RGDPPGDPLGPWMETEGGLHYASELIELIKAESEFEKFEIGIASFPEGHYRSPDLDHDTQ
YTLAKLRAGAEYSITQMFFDIEHYLRLRDRLAEADPVHGVKPIIPGLMPITSLRSVRRQV
ELSGAQLPSDLEERLIKAADGDEQANKDEIRKIGIEFSTNMAERLIAEGVPGLHFMTMNF
ARASQEVLHNLGMAPAWGTGQDMLRGGF
>A0A5E4SPC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea anhela|TrEMBL
MSGSLDNKTIMTQPSFSFEFFPPKTADGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQG
TLDTVIEIQREGVDAAPHLSCVGSTKENIRDILKTYQDNGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGDWFHIEVAAYPEYHPQAKSPRLDLEHFANKVKAGANAAITQYFF
NADAYFRFVDDVSRLGVTVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
ESIRAFGLDVVTGLCERLLKDGAPGLHFYTLNAASATKAMWQRLGL
>S7QEM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gloeophyllum trabeum (strain ATCC 11539 / FP-39264 / Madison 617)|TrEMBL
MKLTEKIAAYKLNRPFYTFEFFPPKTDEGFENLLARVARISSLGPIAVSVTWGAGGATKD
RSLELAGLIQNEEKIDTILHLTCTNMEGGMVDEALRAAKERGVQNILALRGDPPRGEEYW
IPTDPRFTHGVDLVAYIRSSPEFSSAFSIGVAAYPDGHTDRETDEDGELDHLKAKVDAGA
DFIITQLFYDCDNFLRWLEKVRKKGITVPVIPSIMPLQTYASFLRLTKLCGSRVPESVAS
ALEPIKHDDAQVKEYGIALAIDMVKRLTASGDVAGLHFCTLNLEKSVRRVIEGLGWAGGS
PEIKNRLITDPPSQATPSHTDDDLTITPTSASDSATKGLIGSVLPPPDAGRGEINNASSW
DEYPNGRFGDFKSPAFGLQDQWGGPVITRGEALQKWGNPTTVQDLTEIFLKHLRGEVDST
PFSQGPLSPESMLILTELEKLNRHGWWTVGSQPAVDGVPSTHEVFGWGPPSGYVYQKGFV
EFFADQEEVDKIEKRIREDGQGWVDYFAGNFQGECRSNVPDGGRNAVTWGVFPGQEVLQT
TIIERESFLSWKDEAFSIWCEWASFYPPDSEERKLLEGVRDRRWLVSIVHHDYKDASALW
TFLGGDALLSKSVP
>A0A432JR70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPTTNHPNGRRRPSVLTRGDRAVHRRLLEGMTYELIPLRNIHDQSKFLPPGATISVTCSP
AKTIDDTLDLCEQFGDDGFTTIPHFAARMVEGEDHVDRIAARVAGLGIRRVFVIGGDADP
RGPFTDAAGFLRSFLDRGPDIDTVGIGSYPDGHSTIPEQALVDALLEKQEMIAAAGLEGY
MSTQMCFDAGTIGEWLALRRSAGVTLPCHLGVPGAVDRTKLLTISIRLGIGHSARYLKKN
RTSVIRLLSPGGFNPNKLIAPLSRRADDLDIAGIHCFTFNAVDTTEDWRQKSLRDLKR
>A0A434P3H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M5C.F.Ca.IN.020.14.1.1|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAHDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A4P5RHQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MQRPFSFETPNGQPIFSLEFFPPKDEKGEAHLWVELTELNSLHPEFVSVTYGAGGSTRER
TVRVTSEITARTGLRTVAHLTCIGSSKAELSEILDQYWNAGIRDILALRGDPPTGPQSEW
IPTVGGFTHSDELVSLAVAANFNVGVAAFPDCHPASYGNYSADVLVLLEKERRGAQFATT
QFFFSAEKYFNLVKKLRERGSKLPIFAGILPITQVKQLNRMAQLGGTPIPPAIMKAFIEV
ENEPEKVKALGIEIAVNLCNELIAMGVPGLHFYTMNSAYATKEIVKRIGLR
>A0A5B5WS44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia sp. BIOML-A61|TrEMBL
MHLKERLQSGAGPTLSFEFFPPKNEQAAAALYQTIRELEPYRPSFVSVTYGAGGSTRELT
REVVLRIQNESRIPTVPHLTCVGHSREEIWNILDRYAQAGVRAVLALRGDPPRGVGHYDR
SADAFKYAADLVTFIREYNESGHHPDPGGFAIGVAGFPEGHPSTPNRLREMDFLKAKVDA
GADYICTQLFFDNHCFLDYRERCLLAGIKVPVLAGIMPVTSLSGMNRMAELSGGTCFPAR
LLKALKRTGGNPDAIQEVGIQFASSQCAELLDAGVDGIHFYTLNQSRATRQIYRNLGLRD
SLQLLEHGEDK
>A0A7Z2LGP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas asturiensis|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKADLRGLLSQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VGFIREETGSHFHIEVAAYPEMHPQARNFEDDIKHFVNKANAGADSAITQYFFNADSYFY
FVERVQKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITEMCERLLQGGAPGLHFYTLNQADPSLAVWNNLKLPR
>A0A6P8BAD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnaporthe grisea|TrEMBL
MDKITDKIAALPPDSSYFSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
AQKSLELAEICQRELALTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRPGE
YAIADDSEGDVNEFTWAIDLVRYIKRNHGDYFCVGVAAYPEGHAEESHPTNQSLEHDLPY
LVEKTQAGADFIITQLFFDISAYDNFERTLREHPSGAFKDIPIIPGLMPIQNYQMIKRTT
KLSHAKIPDPLMARLDAVKKDDEQVKKVGVDIISELVDQVKEVKNRSSGPKGFHFYTLNL
EKAVSFIVERTNLIPPSTPDDDEVAVLDDVAVPSIHLNGATPVNDHVSASSLHPPTHAGS
RRQSTIGSDPRNRVIVSSGRPASHPDYEATGFEASVPAQAINSRANTLAISEGEGVLGRE
ATWDDYPNGRWGDARSPAYGEIDGYGVSLHMSGTQAVQLWGRPATVEDVSNIFMRHLKGE
LPAIPWSEEEFNAETETIRDTLLALNSRGWWTVASQPAVNGLRSNDRTFGWGPQNGFVFQ
KAFVEMFLPNKDWKELREKLLREKDIVCFYASNAKGDFESSDGGGDAPDGAPTGNGIEDE
QPLPSGSSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWAEWAKVYGKDSPSEKL
LESLRADLWLVNIIHHDYIEKEALWDLLLK
>A0A646MF26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKHHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KKAKSFLIKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
SGKEFSPEITHFSCQPTSKQLIKYRQLHVMYEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKDKLIPTVPLETRGTSSWKNWYLATEA
>A0A1F8M9U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_51_36|TrEMBL
MKTKSNLERVLESKIFAVTGELGPPQSADADVIRRKAKILKGHVDGCNVTDGQTAVVRMS
SWAACLIAKEEGLDPIVQMTCRDRNRIALQMDVLGIAALGMNNVLCLTGDHQKFGNHPTA
KGVYDLDSVQLVKMVKDMRDEKKFQCGEVMAVEPHLFIGAAENPFADPLEFRAVRLGKKA
TAGADFIQTQIVYNVDKFAEWMRMVRDKGLHEKVKILAGVAPIKSVGAARYMKTRVPGMD
VPDGVVARLQGVPKEQVSKEGIKLCIDIINQVREIEGVAGIHLMAIEWEEAVPEMVEAAG
LLPRPKFVT
>A0A1G9MS94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycomyces sambucus|TrEMBL
MTLGTPSVMPVKAAKIGDLLRTGEPKFSFELFPPRDERADGVLWRTIRDLERLGADYVSV
TYGAGGSTRQKTVETTNLVNAETTLLTMAHCTAVDHSVAELRNLIGHFANVGVRNILAVR
GDPPGNPRAEWVQHPEGILHARELVELIKESGDFSVGVAAFPDGHPRDVDWDTGVRYFVE
KCRAGADFAITQIFYGVEDYLRLRDAAAKAGCDLPIVPGIMPITNIRQIERFAVLTGMDF
PSALADRLHAVGDDRDAIRDIGVEVATDIGSRLLAEGAPGLHFTTLNHSRSTRRVWQNLR
P
>A0A1F1Z9X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC29G08|TrEMBL
MRGTIASTRLSASAPLDTAEEALGTHPGADQGVSRRSRTALSFELIPPRNTADTEKLDDL
IAGLAAYHPDYVSVTSSMRSDWLEGTSALIARIASTTDLRPIAHLACTAGTKVELEGWIR
QLIDAGVRGFLALRGDLQPGQEALPEGYLAYATDLLNLINEVQEEEAFRLAAGKLALSVA
CYPSGHAESKNFDHDLDVLLAKQRLGADFAITQLFFDAADYLEFVEVARMAGVRIPLIPG
IMPITSLARAKRMGQLSGLEVPRGVEKQLSSAATPEQEYELGMELSADLARTILNAGTGG
LHIYTHNNLAVTRDLLQRIGIEHKD
>A0A2T2VG47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium SW_8_64_56|TrEMBL
MKVTEHFDQASEPLISYEIIPPKRGGSADQILRVVEELMPFDPPFIDVTSHSAEVEYKQQ
DDGTWQRCVKRKRPGTIGLCAAIEARFGIDTVPHLLCKGFTREETEDALIELNYLGVENV
LAIRGDDKGYEKSISGNRSRNEQAVDLVRQIQDMNQGTYLEDMMNAEPTDFCVGVGGYPE
THFEAPNLAWDIMRLKEKVDAGADYIVTQMFFDNEYFFNFVDKCREVGIDVPIVPGIKIL
KRKRHLRLLPKYFHTEIPEELAAEVDAADPDDVENIGVDWAIRQTRELMEAGVPCMHFYI
MSSADTVKKVVEPLHEMA
>A0A317D2D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. 4G51|TrEMBL
MALGLPSVLPNPQPAIGELIRVGQPTFSFEFFPPKTEQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVPHPQGVQYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFEADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFERVADDPEAVRLLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWQHLR
AGARV
>A0A518FZ94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia panareensis|TrEMBL
MRISEIYRSGTFGLSVEIFPPKSESGDAELFRTLEDLVRYQPAFVSCTYGAGGSTSKRTI
ELCDIIQKQLQTTATAHFTCVGSTREQLLAWLQEAADVGISNIMALRGDPPKGEETFVPA
DGGLKYASELVTLIRENFPDMGIGVAGYPEVHPEALTPQADLENLKRKVDAGADAIYTQL
FFNNQHFYRFQERCAQAGIDCPIIPGIMPITEFRRIQRIMSMCSSEFPADLVNRLEAAQD
DLDDQFEIGVEYAINQCQELIDSGVPGMHFYVLNRSQACKRIFDALGWHEDQA
>A0A6C8GF98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Adelaide str. A4-669|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>L0EF42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4)|TrEMBL
MKPVLRDALRTAVLTGDGAMGTYLHQLGYPIGVSYEEFNMTRPETIASLHKQYYDAGARV
IETNTFSANAERLARYGLEDEAARINREGVRIAREAVGADAWVVGAVGAIRTGRLTAVGT
PAVERAFAGQIDALLDAGVDGILLETFYDLDELLLALRLVRDRSDVTVICQLAAVGTGLL
YSGLPIGEAFRRLEDAGADAVGFNCESGPNGILHAIDALDGAVKLPISVFPNAGGADYVD
GRYTYAAGPAYFGDCARRFADRGARLIGGCCGTTPEHVAAIAASLAGWTPGAAAPERTAE
AVQASAPQIRVNAEPAPTGGGEAPGGGDGPTIVELVRQRPTVIVELDPPRDLDTSKFMAG
ARALRDAGADALTMADNSLAVTRMSNLALGAIVKEQVGIRPLVHIACRDRNLIGTQSHMM
GLHALGIDHVLAVTGDPAKFGDLPGSSSVYDMTSFDMIRMIKQLNEGIAFSGKPLKQRAR
FVVGAAFNPNVKHLDKAVRRLEKKVESGADFIMTQPVYDAALIERIADATRHIGVPIFIG
IMPLASGRNAEFLHNEVPGIELSDEVRRRMAGLEGEAGRTEGVRIAEELLDAALSFFNGI
YLMTPFMFYDMTAKLTGYVRAKASVKTSVISCSSGENELK
>A0A7I9TQM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A8J2YSU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliidongia dinghuensis|TrEMBL
MTQSTPHVASTPVAVSFEFFPPKTAEMEQKLWQVIERLAPLGPRFVSVTYGAGGSTRERT
HATVRRIRHETALEPAAHLTCVGASRDEIDEVVRDYWAAGIRHLVALRGDPPAGASRYEP
HPGGYAYAADLVEGIRRIADFEISVAAYPETHPEATSAEADLDNLKRKIDAGATRAITQY
FFEADTFLRFRDRARKAGITVPIVPGIMPVTNFGQIVKFSAACGATVPASLARAFEGLDD
DPETRRMVAATVAVDLVRKLEAEGVADFHFYTVNRAELTVAICHMLGVRAPLGALPSAPA
LAV
>A0A7L4J202|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pomatorhinus ruficollis|TrEMBL
MVNETQQTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTQDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKDELEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A4Q7UQE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sediminis|TrEMBL
MPDGFRVICEIEPPTRPDLKHARHQIGVLSPVSDSFLIPDNHIGRATVSSIAVANEVQAM
GGSSIACVNSRDRNLLGFRRDLLTAAAYGVDQFLFVQGDKPSVGDRTGELTVRAMIEEAR
AATDQAPFAGVEPFRLGVTAGHRRRMAGWKQAADFIFVQVGYSVDAFLRWREANPTDLPV
YAGVMVLASAGMATRLRASIPDIEIPDDLVDRVASSPAAGVDAACEQIQALRGTGAFAGV
HLVPVSRFREVAAQLERWL
>A0A0A2AL47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus str. MIT 9314|TrEMBL
MKSKLQQTLEKRSKVITAELMPPRGGSPIRSLKIAQLLKDKVHAVNITDGSRAVMRMCSL
AMSKLLLENGIEPVMQISCRDRNKIALQSDILGANALGIRNILCITGDSVKAGDQQDAKA
VHEFESVRLLQQIQAFNEGIDPTLGELSDKKTFIFAGAAADPNCRNKRSLENRMRKKKEA
GAGFIQTQMVMEKENLIDFCEKISKPLEIPVIAGVFLLKSYKNALFINKYVPGANIPENI
LIRLKDAKDPLQEGIKIAAEQAHDFINIANGVHLMAVKAEHLIPEIIEKASLSLEY
>A0A5Q0WQG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella parapertussis|TrEMBL
MTQSTAPAFSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRT
LRNLGCDAAPHLSCIGATRDQLRDILAAYREQGVRRLVALRGDLPSGMGGDAGELRYASD
LVAFIRQETGDWFHIEVAAYPEMHPQAESPSADLAHFVNKVQAGADAAITQYFFNPDAYF
DFVERAQAKGVAIPIVPGIMPITNHTQLVRFSEMCGAEIPRWIRLRLAEYGDDKASIRAF
GLDVVSELCQTLLENGAPGVHFYTLNHAEATLGIWKALNA
>A0A2X3I9E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae|TrEMBL
MARTLASAIAPTSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRG
DLPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANR
AITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMF
EGLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A5N7A2N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus caelatus|TrEMBL
MFPFPLIGGPVKLRPKPFPPRWISPQSSFFNHHLSRNFAGTDSGNKMEKITDKIAALPPD
ANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGTTAQRSLELAEICQRQ
LQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNRDFT
FAVDLVRYIRQKYGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTQAGADFIMTQ
LTYDIEAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVQIPPQILSKL
EEVKHDDDSVKRIGVDIITNLVDGMRDIPCPGLRGFHFYTLNLEKTVSFILERCDLIPPY
SEDFDAIEDGGDISAMDGAQLRSLTRRRASSINSLPHNRVIVDKLQASEGSSKASVSHEA
PATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLH
VPPSVAHRIWGFPVSREDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELL
QLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLL
QKHGHEKLAWFAANGKGDFESSLPAQTSDADPIEMNPNNVNTVTWGVFRGKEIVTPTIIE
EVSFRAWGEEAFRIWDEWRRIYPRNSATERFLNETKDDVWLVCVVGQDFGAGTEMGSEEE
EDEKKFMWRVLLNAK
>A0A3A9XM01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimarina sp. AD1|TrEMBL
MKVTDHIKNAKGKTLFSFELIPPQKGKSIQELYNNIDPLMEFKPPFIDVTTSREEFIYID
RDGLLDKKLTRMRPGTVGICASITHKYNVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFNPTKGGHCYANELVEQIVNMNSGRFLHEVIESDNQSDFCVGVAGYP
EKHLEAPSMDSDIRRLKDKVNAGADYVVTQMFFDNKRYFEFVEKAREAGINVPIIPGIKP
VAVKRHLQLLPQVFKLDMPDELVKAVESCKTNKEVREVGIEFAIQQSKELMEYGVPVLHY
YSMGKSDNIKKIAANVF
>A0A327TWC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora sp. SolWspMP-SS2h|TrEMBL
MALGIPSTRSDRAQTVRDLLAAGDRSFSFEFMPPRNEEGERRLWDAIRRVECLEPNFVCM
TYGAGGSSRGRTVDLVGRIATETTLTPVAHLTAVDHSVAELRNIIGQYADQNVRNVLAVR
GDPPGDPMGEWVRHPEGVSYAAELVELIRDIGDFCVGVAAFPQMHPRSADWDEDIRHFVA
KCRAGADYAITQMFFEVEDYLRLRDRVAAAGCETPIIPEIMPVTNIRQLVRFPQLSGSDF
PADFRRKLEAAADDPAAVRAVGLEHATAMAERLLAEGAPGLHFITLNHSTSTLEIYQNLG
LHTR
>A0A0D6QEL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeromyxobacter sp. PSR-1|TrEMBL
MRITDLLRFARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTR
AKTIDLVKRLKRDAEVEAMAHVTCVGASRDEIAAVLDEVADAGIQNVLALRGDPPRGQSA
FVPHPDGFTHASELVAFIRSRPERWRFCVGAAAYPEGHVETRDLAQDLRNLKLKVEAGTD
FLVTQLFFENAHYFRFVERARAAGVEVPVVPGIMPFTNVEQVERFTAMCGAAIPPPLRAA
MEVRRADADAARELGVAYATLQCADLLRRGAPGIHFYTLNRSPSTRAIVAALRASEPWRG
>A0A1Q5I216|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02009|TrEMBL
MALGTASVRSDRARTVREILASGGTSYSFEFFAPRTEKGEQVLWNAMRRVEAVGPSFVSV
TYGAGGSTRGGTVKATQKIASDSTLTPVAHITAVDHSVAELRNVLGQYADAGIRNMLAVR
GDPPGDPLGDWVEHPEGVTYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEKYLRLRDSVAKAGCETPIIPEVMPVVNVKTLDRLPRLSNAHF
PADVKERILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTAIEIYENLGL
HQQS
>A0A4Q7UXK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sediminis|TrEMBL
MRPPMPSTTARDDPAATVGCPKHMTYGPCGGVRADLGCEVAPVPCPFATAPGPVPWAGPP
APPRPEPDLFVRTRGRPVVLTDLSVPPYDAATLQRTVSVLAGACDAILVGEHHDEPDFPP
TMLAALVGEAGGHPWITLTCRDRNRVVLEQEVAGLAAIGTDGVFCATGDGRAPGVRPDVT
PVFDLDGTRLTALAAAAGLAVAVPEAPDAPPRGNRPGRLAQKQRAGAQLAVLNHAGSAEH
VAAFAAAVRDEGGSLPIVAGVAVYTDEASARRLQAYPGLELDPDRVSDVLTAADPVEAGI
AAAVAEARELIAVEGVAGVNLSGRGTSAGLAESTAIKAEIGRRIRSGT
>A0A1Q8SRM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinicola socius|TrEMBL
MSTQPPLGVSFEFFPPNTDAGREKLGGVRDALAAREPRFFSVTYGAGGSTQARTFDTVKT
VRRSGVTTAPHLSCIGSEKGALRELLQSYREDGVDSLVALRGDLPSGMGGAGELRYANEL
VEFIRNETGDHFEIAVAAYPEAHPQAPSFERDLENFARKAKAGADIAITQYFFTAEAYFH
FVDRVRAMGVETPIVPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDGNSIQAFG
TEVVSDLCQRLLDGGAPGLHFYTLNQSAPSLRVLDNLSL
>A0A1B3BB74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kangiella sediminilitoris|TrEMBL
MASLNNKAPTYEEARIAEFLNEQIADLDGKVNVSFEFFPPKSPEMQKTLWKSIKKLEPLN
PEFVSVTYGAAASTRSRTHDVITKIIRETGLTAVPHLTCIGSSESEIEAIAEDYWEKGVR
HIVALRGDLGDDSKTGDFQYATDLIHKLKSLHDFEISVAAYPEVHPEAESAESDLQNLKR
KVDAGASRAISQFFFSAEKYLRFRDRCDEEGIGIDLNPGILPVTNFPQLLKFAKFTQVDI
PEWMFKVYEGLQDDPETSRLIASHIAIEQVKLLVKEGVEDFHFYTLNRADLTYAICHSLG
KRCLPSVA
>A0A1C2Y5K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. TeCB1|TrEMBL
MFISELFQQKKVVSFEIFPPKLTLSIEVIYDTIDALAPLRPDFISVTYGAGGSTSKTTAE
IASIVENKYNINSLAHLTCITSSKEQIEGTLTQLADSNVSNILALRGDIPKGSEETGRVR
DFQYASDLVAYIQNKHSFCLGGACYPEGHPECPDKDQDIENLRRKVDAGVGFLVTQLFYD
NDAFFRFQEKVAKLNINVPILAGIMPITNRVQIERILALSNARMPQKLIKILDKFEHNME
ALKDAGIAYATKQIVELLANDIDGVHIYTMNKPQIAKDLVRNLDSLFYAVNSQETRKVGN
LD
>A0A6P7EJY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ovis aries|TrEMBL
MDRPKPKVFPVGHCCPSLGMRALEAGSGRLSVPPSISRISAMVNEPRGNGGPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEGESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLSRPPQDERETEAL
>A0A8F2JAL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. MSJ-33|TrEMBL
MIQEKEHSGVVFSCEVFPPKRDDDIYQIYKTLDEIKTLKPDFISVTYGAGGSNSKKTATI
AAYIQNICEVEALAHMTAVGMDEAGLRALLFELKKKGVENILALRGDKPRTMTQEEFDQR
YFKYATDLIPEIKKNGDFFIAGACYPEVHPESKNQEDDIRHLKQKVDLGLNCLITQMFFD
NNAFYSFMDKLEKAGINIPVHAGIMPVTAAKQLGTSVTLSGSSVPVEMSNMIAKYGENPE
DMKKAGIEYAVNQILDLKKHGVAGVHIYSMNKADVTKQIYEASF
>K0KI23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wickerhamomyces ciferrii (strain ATCC 14091 / BCRC 22168 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL Y-1031 F-60-10)|TrEMBL
MSALNPLFVTITWGAGGSTAEKTLSLVQTCQKELDFTTCMHLTCTNTDKSIIDNALAKAK
EAGIRNILALRGDPPRGEEYFVPNAADFQYAVDLVKYIKQQYGDYFSIGVAAYPEGHCEG
ADNSEQEVLKDLPYLKEKIDAGADFVITQLFYDVEKFLHFENLVREQISQDIPILPGLMP
INTYQLFNRAAKLSHASIPSEILGRFPENIQNDDDKVKSIGVEIMRDMIHSIYSRTNGRI
KGFHFYTLNLEKSIAQIVEKSSLLNRVLENDDQNDEDAIMSDDDENQPIAPQHKIIGHKD
KSRRSSSVNTSNKVLVDRIRKDSQDFEDVNKYKFITPSKKDIVAISSGEGTLGRDATWDD
FPNGRFGDSRSPAYGEIDGYGPSLKIATKKAYELWGYPVDTSDVSKVFINYLEGKIDALP
WSELGLSPETAMIQEELIQLNERGFFSLASQPATDGAKSEDKIFGWGPKGGYVYQKAFVE
LFVSREDWEFKLKPKISQNSKITYYIGDSKGGFESSLPGKSSNAVTWGVFPDREILQTTI
IEEESFKAWRDEAFSIWLEWAKLYKKSTPTSKLLNHIHDNYILVSIVSHDYRNETGLWEL
ILN
>A0A562J0W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sedimentibacter saalensis|TrEMBL
MHITDIFNKKKFVFSFEIFPPKATSSIETIYKTLESLSDLRPDYISVTYGAGGGNNQNKT
REISSIIKNKYGIETMAHLTCIRSTGEEIIDTLRDLKKEGIENILALRGDIPLEEEVKGD
FQHASDLAEFIMSRDNFDLGGTCYPEGHVDCKNLEEDVKNLKFKIEAGVTHLTTQLFFDN
NDFYNFLNLAEKHNINVPIQAGIMPLTNKSQIERIVTLSGSKIPEKYIQIMNKFEYDKDA
MADAGIAYASEQIIDLMANGVDGVHLYTMNNPYVARKTHNNIISLVHSLNREI
>A0A2E0W2Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium|TrEMBL
MKVIEHIEKAKKPLISFEIIPPKRGGDVKQLLSILEEIVKYNPPFIDITSHAAEAIYEET
PDGGFKVKVKRKRPGTLGICALIQNKYNIDAVPHVICQGFSKEETEDFLIELHYLGIDNV
LAIRGDDNGFRKPLQYGRSANSFAVDLVRQIASLNKGKYMEDGLLDAKPMNFCIGVGGYP
EKHFEAPNLLTDVKYTKQKVDAGADYVVSQMFFDNQKFFSYVDACKANGINAPIIPGLKI
LTNKKHIQSLPKNFYIDIPDELANEVMEAKPEHVLDIGVEWTLKQAEELLNKNVPAIHFY
IMQDPKPIKKLMEKLDI
>A0A5N0T7Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenzhouxiangella sp. W260|TrEMBL
MKCSFEFFPPRNAEQELVLQSTWQKLARLEPGYLSVTFGAGGSTQEATHRTVLDLIERSG
VPVAPHISCMAPSLDVLDRLLDTYAADGVDRLVVLRGDWPEDADFTPPFRYASELVAHVH
DRHPGRFSVEVGCYPEIHPESESMDSEIRWFKEKVDAGADAAITQYFFNADAYFEFVERC
RAAGISIPIIPGIMPITNYTQLARFSARCGAKIPAALAEKLQSFGDDGAAIRDYGLDVVT
KLCEDLVAGGAPGLHFYTLNRANATMKIWQRLNGDHSSP
>A0A0G4C065|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis M0579|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A1V0GD81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. FDAARGOS_192|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKDQAPQFDIIGACYPEGHPDSANQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARQIHEATHSLFKHHSQVGAL
>A0A2G6E5V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium|TrEMBL
MKVIEHLAKANDTLISFEIIPPKRGGNFKTLLEALEDLVKYNPPFIDITSHAAEVDYEET
TSGEYRIKIKRKRPGTLGLCALIQNKYNIDAVPHVICQGFTKEETEDFLIELHYLGIDNV
LAIRGDESGYRKPVKFGRSINTYAIDLVSQISAMNKGKYLEESLLDAEPTSFGIGIGGYP
EKHFESPNLTNDIKHAKSKINAGAEYIVTQMFYDNRKYFDYVKLCKEQNINAPIIPGLKV
ITSKKQLNSLPSNFYVDIPMELAEEIDSAKPEHVGEIGIDWAIKQSEELLNANVPAIHFY
VMQNTKPIKKVMERLFK
>K0KJW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wickerhamomyces ciferrii (strain ATCC 14091 / BCRC 22168 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL Y-1031 F-60-10)|TrEMBL
MRISHKLEQSHKENDIPTFSFEFFVPKTSQGVQNLYDRMDRMYNVNPQFIDVTWNAGGRL
SNLTTDIVQTAQSVLGLETCMHLTCTNMPVDLIDKALKEAYDSGCQNILALRGDPPVEGG
EWTAVEGGFQHAKDLVKYIRNKYGNHFDIGVAAYPEGHPEETDIDLLIGFLKEKIDAGAD
FIITQMFYDAENFIEWCQKLRDQDINVPIIPGIMPISTYASFKRRSTWCEIKVPEEFENK
LLANKDDDQLVRKIGTELVAEMCSKLINSGFVKHLHFYTMNLEKSSIMVLEKLGLINSNE
QTQNNTEALPWRKSLNPNRNSETVRPIFWKNRKYSYITRTQDWDEFPNGRWGDPNSAAFG
DVELFTSGLLRQSSKRCIELWGEPKNFKDVSQLVVKYLQGEVNSLPWSDTPITAEIDSIK
NELIEINQNGILTINSQPRVNGEPSNHPAFGWGPKDGFVYQKQYLEFLMPKSKILKLISK
IELINKPFNLSTNQKDNFNYLTYFAIDFNDDLITNSKDDSANAVTWGIFPGQEVLQPTIV
EKVSFLAWKDEVFRIAEEWSGIFEDGSDSKNTIKTIINDYALVNIVDNDYVGESKIFDLL
KQL
>A0A2S3UME3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium marinum|TrEMBL
MSDQRPSATGRLAASTEMSPRQVVEKTELLAHIPAGTQVYVTDLGNAPEEMIVAAARMLT
ENNLIAVPHMAARRYPSFEAFETRIKRLTQEAGVTEVLAIAGEAETPGPLTSSLDLLESD
LFGRLGIRKIAVAGHPEGAPDISPEVIRSFLSRKHEIAANSDAEFRIVTQFGFDPHRVSL
WLDELRAWGNRFPVHVGVAGPAKMTTLLKYAAFAGVENSLNFLKKRGGAVVSLLSGYDPE
TMVGPLEKRLTSQPECQLAQIHVYPFGGIEKTANWLHDRKSWSFRTPSSSLTVTESA
>A0A521EPJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia kunjamensis subsp. schimae|TrEMBL
MTQLPDSDPTDGGRHPSIVERIATSTTPRVPFSVEFYPPRDEAAEDRLWRAATVFSDLGA
AFVSVTYGAGGSTRDRTVRVVERLVRETDLLPIAHLTAVDHTVAELTDMIRMYGEVGVSN
ILALRGDPPGDPLGEWTAHPEGLHYAEELVRLIHEVGGFHVGVASFPEGHYRARDLEHDS
EILVNKLRAGAEYSITQMFWDVEHYLRLRDRAVAADPEQGAKPIIPGLMPVTSLRQVQRM
VELSGCALPDDLAERLRTAAGDGPEENRAAVREVGIDLTTRMCERLISEGVPCLHFNTLN
FSKATHEVLTNLSMAPAPGVAAGRI
>A0A319EPD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus sclerotiicarbonarius (strain CBS 121057 / IBT 28362)|TrEMBL
MTRSLAAMGSAVRHAAFSGGARKSSSPPPSSSFTPFLFIRPDVCDRVAAAETGLTMEKIT
DKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGSTAARSL
ELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHG
EDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDGQDPERDLPYLVEKTQ
AGADFIMTQLTYDMDAYTKFERMLRNHESGAFKTIPIVPGLMPIHSYKILTRVTKLSHVK
IPPQILAKLEEVKHDDDAVKRIGVDMISDLVYGIRDLGCPGPRGFHFYTLNLEKTVSFLL
ERCELIPPYSEVDESDALVDGGNLSAMDSSSYVAPNGAQIRSLASRRSSVSSIPHNRVIV
DKVQISETSSKGSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWG
DARSPAFGEIDGYGPSLHVPAPIARQIWGYPVSREDISTLFRRHVSGELYMVPWSEGGAE
ENSNGLNAETAVIQSELLTLIDKKGWWTLASQPAINGVRSSDPVFGWGPPGEGFVFQKPF
VEFFCPDKDYQTVLKPLFQKHGHDKLAWFATNVKGDFESSLPGPNPDDADPIDINPANVN
AVTWGVFRGKEIVSPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDQTKKDVWL
VCVVGQEFGAGTESGSEEEEDEKKWMWRKLANSQ
>A0A1V2KN61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. CcI49|TrEMBL
MRESTTSNEQPARGFELICEIEPPTRPDLTHARHQIGVLSPVADAFLIPDNHIGRATVSS
IAVAHEVQTMGGRSIACVNSRDRNLLGLRRDLLTAAAYGVEEFLFVRGDKPSAGNRTGDL
TVRAMIDEARAAGEDPVFADMPAFRVGAAAGLRPLPAWKQAADFLFVQVSYSVDALLRWR
DAHPVELPVYAGVMVLASAGMARRLAATIPDIDIPDDLVQAVERDRAAGVEAACDQVLRL
RDSGAFAGAHLVPVSRYRQVAARLEDLL
>A0A8I1LMA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MSRPGLSFEFFPPRDPAGRERLDAAARALAAFGPRFVSVTYGAGGSTRTATLDAARRLGR
LPGLRVAGHLTCVGATRAETLSVARAYAAAGLRDIVALRGDPPRGQGGFVPHPDGFRDSV
ELIAALKAMGDFRIHVGAYPDRHPDAADADADIVWLKRKFEAGADSALTQFFFDPETFFR
FRDRAAAAGIDADRIAPGILPVQNWTKVQQFAAGCGAAMPPQIAQGFENAARQGNERLYA
LAQATQLADRLVEGGVRHLHFYTLNSAGLTRDVCRALGMRARPFLADAA
>A0A2R7UP56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas plecoglossicida|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSAERFAAMEAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSRQAAPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAKSK
AFALARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPMWATRLGAQVLHKVEHAVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAMRQTELLTERLIPCIELETRHRSSWPQWFQAQTP
RQFSSQPAPRTQPES
>A0A8F8L0L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gramella sp. MT6|TrEMBL
MKITEHLEAAKDKTLFSFEILPPLKGQNINSIYESIDPLMEFNPPFIDVTYHREEYVYSE
KENGLLEKKIVRKRPGTVGICAAIQSKYGVDAVPHILCGGFSKEDTENFLIDLDFLGIKN
VMALRGDAVKSETYFKPEKNGNCFAKDLVDQIYDLNAGKYLDEVIEKGHNTDFCVGVAGY
PEKHMEAPSIDKDIQRLKEKIEAGAEYVVTQMFFENDRYFDFVEKCRESGIDIPIIPGLK
PIATKKQLSVIPHRFHVDMPDCLIREVEKCKDNAAVRQVGIEWCIQQSKELIAGGAPVLH
YYSMGKSTNIQKIATAVF
>A0A6B3BLN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID12501|TrEMBL
MGASGLRALLERVRYEVLPAKSTEDKVLAHVPRDVVITVTASPVKGLEPTLDLVGRLSAH
GYRVVPHVPARLLRDDAHLKDVVDRLRETGVDDVFVPAGDADPPAGAYEGALPVLRRLGE
LGSPFTHVGVTGYPESHPLIHDDVTIQAMWDKREHATYIVSNLCFDARVLGEWVGRVRRR
EVGLPVYVGVAGPVQRAKLLSMATKIGVGESTRFLTKHASWFLRFAAPGGYSPESLLSRA
EGPLTAPGAGVAGLHLFTFNQVAETERWRCALLDRLDG
>A0A7C2DXR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MSVRPRVSFEFFPPQSLDASFQLWQAVRELQPFAPDFVSVTYGAGGTTRTLTHEAVTTIG
RRTGLKVAAHLTCVGAARSETMKIAHDYAEAGVTEIVALRGDPPKGAGRFAPHPLGFPHS
VALIEALAATGRFTIRVGAYPERHPDAADARADIDWLKRKIDAGASSAITQFFFEADTFF
RFRDACAAAGIAAPIIPGILPVASWAGAKRMAQRCGASIPARLDAAFTTAQRDGREELYA
LAQCTQLCDRLVEGGAERLHFYTLNRPDLTARVCRALGIEPAAALERVA
>A0A068YU11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp. CG9_12|TrEMBL
MNIPVSFEFFPPKTPEGVDKLCLTRQALYACQPEFCSVTFGAGGSTQEGTFSTVKAILDE
GEAAACHFSCVGATQATVREQLAALRAMGVKRLVALRGDLPSGYGAGGEFHYASDLVAFI
RRETGDAFHIEVAAYPEIHPQAKSADADLQAFAAKVRAGADSAITQYFFNADAYFRFVDD
VQRLGADVPVVPGIMPITNGAQLMRFSDACGAEIPRWIRLRLQGFGDDTASIRSFGLDVM
TDLCDQLRTAGVPGIHFYTMNQAAATSEIIRRLTPA
>C0ECI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] methylpentosum DSM 5476|TrEMBL
MYIKKLYQIKRPVLSFETFPPKQQSALETITDTLGQLTALHPDFISVTYGAGGSGNSGKT
TEIASMIKNEFGVEPLAHLTAITAKRETIHNTLADLKAHNVQNIMALRGDIPVGFEGDPN
GDFVYAADLIREIKQVGGFCVGAACYPEGHIDCDSLPNNYAHLLQKQEAGADFLISQLFF
DNAQFYHFLERARRAGVTIPIVPGIMPMMSKSQVQRMIFTCGVSLPSRIIRILHKYENDP
QSLEQAGIEYACEQVTDLIKNDVDGIHIYTMNKPQVAAACKSRIDFLLK
>A0A503TUJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-3-12|TrEMBL
MTGPQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHDEITETQVDMVK
TAH
>A0A2A5F654|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTYKTSQTTSLSFEFFPPHNAEASARLWRSVERLAPLGPEYVSVTYGAGGTTRERTVSAI
KTIQDRARLCVAGHLTVVGASRAETLDVARGYAAQGVRRIVALRGDAPKGQDHFTAHPDG
FQNAAELVAGLKEAGDFEISVAAYPEKHPDSADMKADIANLKRKIDAGASSAITQFFFDN
EDFLRFRDAAADAGITAPIIPGILPVENFTKMLRFADMCQAKVPDWMHQAFRNAGDDAEV
LATAICAEQCDELQAEGVDHLHFYTLNNPDLVYNICRALGFEAVGVDLAASVA
>A0A367X9U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira profundimaris|TrEMBL
MTQLRDTTHQTAANRRDLRVSFEFFPPKTEKMEETMWRSIHRLAPLAPSFVSVTYGAGGS
TRDRTHASVTRIQRETGIPAAAHLTCVGHTRGEIERIARTYWDEGIRSIVALRGDLPDAG
DTYVPTPGGYDYAVDLVGGLKKIADFDISVSAYPETHPDAPSADFEIEYLKRKFDAGADR
AITQFFFDNEVFLRFRDKCAKAGISAPIVPGILPVTNFASLLKFAGMCGANVPARLHHRF
DGLDDDPDTRRMVAFHEAISQVEGLIAEGVTDFHFYTLNRAELTYAICHALGIRAKQVAL
SA
>A0A4D8SWE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TAQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRASGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A3M2RG41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter litoralis|TrEMBL
MQSQKQFKRRFSFEFFPPKTDAGKEKLQVVRDQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGSREEISQLLDEYKANGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARSAEDDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMNITIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTVSIRK
FGEEVVTRMCEDLLKAGAPGLHFYTLNQTEPSLSIWKNLGITDREKISF
>A0A1X0U9A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 1168|TrEMBL
MVDRLRTSTESKIPFSVEFSPPRDEAAEARLWRAVREFEQMQPAFVSMTYGAGGSTRDRT
VRVTGEISENTTLLPVAHLTAVSHSIDELRSMVGAYADRGISNILVLRGDPPGDPLGDWT
KHPQGVEYAEELVSLVRELGDFHVGVASFPEGHYRAVDLEQDTRVLVNKLRAGAEYSITQ
MFFDVEDYLRLRDRVAAFDPEQACKPIIPEIMPITSLRTVRRALSLSGSALPSEIDDRFT
RAAGTGAEEDRAAVREVGIELATSMCERLIAEGAPALHFITLNFARATREVLTNLGLCAA
RV
>A0A2P6FMP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MLRNFSLETTPTGASKITSFSEFIRPTTTVFITFLPGTEYNQTVITARKLRQEGLNPAPH
FAARSIVSKTMLEDYVQRVTGEADIKKILIVAGAGKDQLGPYPDSASLLETGIFDKYGIT
EIGVAGHPEGSPDIPNQKISEALLFKNQFAEKTDANLFIISQFCFDSKTILNWAKNINSE
GNKLPIIIGVPGIAKLSTLLKYSLSCGIGNSMNFLKKQGSKMVNLINNQAPDRLVRDLAR
SNLDGIETGIEGLHIYPLGGLKKSADWAYQALDGNFQLGKDGFTVDGK
>A0A6B3BRC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID12501|TrEMBL
MALGTASTRTDHARTVRDMLASGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVSDTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPMAEWVPHPSGLTYAAELVRLIKESGDFCVGVAAFPETHPRSPDRDTDVTHFVD
KCRAGADYAITQMFFHPESYLRLRDAVAAAGCPTPVIPEVMPVTSVRMLERLPQLSNAAI
PSTLKERILTAKDDAAAVRSIGIEFATEFCARLLAEGIPGLHFITLNNSTASLEIYENLG
LHHPQRA
>A0A317FNS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falsiroseomonas bella|TrEMBL
MNMALSGTLQRWLTGPRVAGLPQPTELPPPKLSFEFFPPKNETLEQQLWTAIRRLEPLAP
RFVSVTYGAGGSTRARTHETVSRLARETSLTPAAHLTCVGATCEEVDEVARGYLAAGVRH
IVALRGDPPAGASEYTPHPGGYAQAEDLVRGLRRIADFDISVGAYPETHPAATSADADLD
FLKRKIDAGATRAITQYFFDTDIYLRFLDRCAAAGITVPIVPGILPVSNFKQVQKFSAMC
GASVPAWMARLFDGLDEDAETRRLIAAVVAAEQVRLLQANGVDEFHFYTLNRADLTYAIA
HLLGVRPQSAG
>A0A4P8QTM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brenneria rubrifaciens|TrEMBL
MSFFHANQREALNQNLAELQGQMNVSFEFFPPHTREMEETLWASIDRLSSLKPKFVSVTY
GANSGERDRTHGIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWQSGIRHIVALRGD
LPAGGGKPEMYASDLVALLREVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPALAI
>A0A6J4L3L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Cytophagales bacterium|TrEMBL
MTKITQYIKEAKKTLFSFEILPPLKGESIQSIFSAIEPLMEFNPPFIDVTYHREEYVYKL
RENGLLEKRTIRKRPGTVGICAAIMNRFKVDAVPHIICGGFTKEETENALIDLSFLGIEN
VLVLRGDPIKSEGVFVPEPDGHRYSTELLQQVVNLNKGVYLDEEMKKPIPTEFCIGVAGY
PEKHFEAPSMRFDLQKLKHKVDMGADYVVTQMFYDNQKYIDYVRRCRQEGINVPIIPGLK
PLTSKKQLVALPRAFFIDLPDDLVDAVEKCKDDAAVKQVGIEWCIQQSKELMEFGVPVLH
YYTMSKSDATKKIATALF
>A0A5J6XRB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pradoshia sp. D12|TrEMBL
MKLLETLNEKILVADGASGTLLYSFGIDSCFEELNLTNPNQIKKMHRSYIEAGADVIQSN
TFGANFHKLKRYGLEREVSQINRAGMKIAKDAADPNTFIIGTIGGLRSFRKSELTLTEIK
GYFDEQLTALLEENPDGILLETYYDLDELLTVIESARKMSDLPLIANISLHETGLLQNGM
HVSEAFSLMKKTGADVVGINCRMGPYHMIRSYEEVPLLEDTYYAAYPNASLPDLSDGRYV
YSTEADYFINSSRQLVKQGVRLLGGCCGTTPAHIQAIRKGIEDLHPVKVKDFVAKPKHQP
ISYEIIQYKRKGPDTISGKAKKQTTVIVELDPPKTFGLEEFLIGSRYLLDSGADAITLAD
NSLASPRISNLAVASILQSKLNTVPLVHLTCRDHNLIGLQSHLMGMHSLGLSEVLVVTGD
PSKIGDFPGATSVYDLSSMDLISLIKQLNEGRSYSGKSLGSRANFDIAAAFNPNVKYIDK
AVQRMEKKIQAGADYFLTQPVFSVEKLEEVYAATRHITKPIFIGIMPLTSHRNAEFLHNE
VPGISLPVHVREAMERAGADKEACARESFAISKELVDAASELFNGIYIITPFMKYELSGH
LVRYIKEQKSVVNKEVHLS
>A0A844EIV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. BIOML-A3|TrEMBL
MKDVREILKKRPLLFDGGMGTYYKAKPGQECEQANLLDPDGILTVHRAYLEAGADAIKTN
TFGLPRMAAAQNPMWEAMADEGWKLAAQAAAKTSAAVFADLGPATDTEALPAAQIYTALA
ERFAALGAKNFLFETLSSDAGVAEAAKKIKETVPDAFVLVSFAVLPDGYTREGRHCAELV
RSMTACGAVDAVGLNCVSAPGAMRALVQQLGETELPLAVMPNAGYPVVTRTRVQYQGRPE
YFARELARLAAEGVRILGGCCGTTPAHIAALRAALDALPETLPAAPAAAVSTAAKPEVEK
DDAFLRKLNAGKKVIAIELDSPKDADLTGYLDGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGLNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPLTVFGALNLNARNFDVELRRAVEKLENGMSGFL
TQPVLSAQAVVNLKKTRETLGEKAKILAGIMPVVSQRNAIFMENEVNGIHVDAEIIERFA
GLDRAQGEELGLEVSVKAAQAAAPYADGFYLMTPFNRIALMERLIARLKDEGIAD
>N9CT61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii ANC 3681|TrEMBL
MEDESKNIESAVVNNQTIRHLFLICTIILLFLILWIISSVMSLLAQYFAQQQFCVLVEYL
SSHQAQWPVKAQFAGFPAAMTLADRVHADDDEAPLQVAKQYPQEIEKVIHFSGKARDIQD
FEQFLQDAKTQGQKNLLLLTGDKLKQHCYSHDLEPRTRYLESVNAVMEAKRQGGFHIGVA
FNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMTALQDAHEFLVQHQYSQKMLACV
MPLTLERAKFMLKHKVAGIVITPHMLQVLQQEKEQGLSDHVYMRCALQILMCRHLGFAGV
HLSACHQPEEQSLLERYIEEYRHSSFAECERLWNTLWQVKTGTEFHPKLTYYSRPATSSQ
IIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDRTKANKALLKTEHLSKHAVVGCESCG
QCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECIHSVKARLAKAVGQTKILKEK
LIPTVSIAVRGTSSWKNWYVEAAG
>A0A6I6T5J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. S04|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VQFIREETGDHFHIEVAAYPEMHPQARNFEDDLANFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLKLPR
>A0A1C3CXY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter celticus|TrEMBL
MTKRVPISFEFFPTKTDVGAEKLRVVHQELQLLNPDFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYQSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFQIEVAAYPEMHPQAESFDLDIQRFCDKANAGANAAITQFFFNPDAYFYFV
DRIQKEGVDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAVYGDDTASIKAFGHE
VVVNLCERLIAGGAPSLHFYTMNQTEPNRQLVLDLGLA
>A0A239NFD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asanoa hainanensis|TrEMBL
MALGLPSILPGSQPSIGDLIREAGPTFSFEFFPPKTPEGEVQLWRAIRELEPLHPSFVSI
TYGAGGTTRDTTVSVTERVATETTLLPMAHLTAVNHSVAELRNVIGRLAAAGIRNILAVR
GDPPGNPNGEWVRHPEGVDYAEDLVKIIRESGDFCVGVAAFPYKHPRSADIASDTDFFIQ
KCRAGADFAITQMFFDGDDYLRLRDRVAAAGCDTPILPGVMPVTRMSTIARSEQLSGAPF
PPALAEQFARVADDADAVRKLGIEQASEMCARLLAEGVPGIHFITLNRSTATREVWQHLR
VDAGV
>K7SF01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfuricurvum sp. RIFRC-1|TrEMBL
MFESFIHKLRHGTYITLETTPSRSAQFAPTIEKIAALGLDKLVDGFSTTDNPLAKLKYNA
LFAAMKLQDRFGLPTLATMSMRDRNRIALQSDLLGANEANVRAILALTGDSAHYSDQPHA
KGVFEGNSKLLLDIITTLNNGTDLAEQKLIAPVQEIFPFAVIDAYAKSAATLQKKMTKKV
AHGAISIISQPVYDLENAKKLLDMMSEANRENNGSCVLVLGYFPITKLRTARFLDENVPG
IYVPIAWVEALEAASLISPEEEYRVGFELSKTLFEELKALHPKIHIMTANQFELAKAILS
>A0A1I1QSZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klenkia taihuensis|TrEMBL
MTAPACPKAMTYGPCGGVAEDGSCEVAPHPCAFLPLPTVRWPGDRVTRPGPEPRLLALLR
QRPVVVADLPAVALSRGSLERCADLVAARVDAVLLGDHAAARVQFPPAYRAALVQARGVP
VWQGLNCRDRNRVALEGELAALADLGVGAVHCVTGDHTATGDRPDAQPVFDLDSTQLAAA
ARAAGLLVSVGETPHGPPAQRRPHRLVEKARAGAEVCFVDHAGGPAELAEFVGAATDAGA
DVPFVACVAVATDPGSVAELRRFTGLRLPAGYLAGIEGARDPRRAGVAAAVALAEAYLAV
PGVRGVDLSGVAAPGTEATTAAALAEIGRALT
>A0A2S3YMW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium americanum|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMEIQLFQTISDLSVFAPAFQTVTYGAGGSTKAR
SLTTVKRMIGEMGLNNTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGSA
YEPFPGGYESSASLVKALRARGDFEISVSAYPEKHPESADVAADIDMLKRKVDSGATRAI
TQFFFDNDDFERYLERVRRAGVQIPVVPGILPINNLTQVIRFAGLCGSKVPEAIISRLAH
LDDQPEERFKEASHIAAEQIVDLARRGLRDFHLYTMNRSPLIAAVCELVGYRRRPVRPAA
APSYPAVATA
>A0A4R4ZIN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella antibiotica|TrEMBL
MANGLPSTLPGSTPTVRELLSSGARSFSFEFFPPKTPEAEEVLWRSLREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPIGHLTCVSHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWVAHPEGLNHAVELVELIRELGDFCVGVAAFPDKHPEASSLEADAQVLAA
KAQAGADYAITQMFFGADDYFRLVDRAAALGCDIPVLPGIMPVTNIKQIQRMAELTGMAL
PTAVTDRLLAVESDPAAVREVGVELATELCEQLLAGGAPGIHFITLNRSTATRQVFQNLS
THVGS
>A0A1M7I0W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga jiangningensis|TrEMBL
MHPHYPANNMKVTEHIAQAKDTRISFEVLPPLKGKSIDSIYDHLDPLMEFKPAFINVTYH
RSEHMFKKKADGSFEKVEIRKRPGTVGICAALMNHYNVDTVPHLICGGFSREETENALID
LAFIGIDNVLVLRGDAPKNESFFEPDPHGHSYASELLGQVVQMNNGIYLEDDLQGGVKTN
FCIGVAGYPEKHFEAPNMQTDLANLKRKVDGGADYIVTQMFFDNQKYFDFVNKCREIGIT
VPIIPGLKPLTSKKQLNILPRIFNVDIPTDFSNEILKCKTDKEVEQVGTEWLIAQSRELK
NFGVPILHYYTLGKPRVVRDAVAAIM
>A0A0J1GEB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robinsoniella sp. RHS|TrEMBL
MKSVIDIMKERTSFSFEVFPPKAEQPMEPLLNTLDELYQFDPDFISCTYGAGGSNAGRNV
EICKAIADSGHRAVTHFTCIGNTKEKMKAELQAYLDNGVNHILALRGDLPAGWEGTRGDF
NYANELVAFIRAEFGDQFTIAMAGDPEKHIQCPTFEEDIAHLKMKQDAGADYIMTQLCFD
IEQFKRWVDQIRNAGITLPIDVGVMPVLNKDATIRMALSMNGCSIPRDLAEVISKYYNDP
EGFKEAGIDYTVHQLYQFIGEGVEGIHLYALNKSAAVSEILTRSGLRAKAE
>A0A3T0E6P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycocaulis alkaliphilus|TrEMBL
MRGGTMPDGRTLPVRPGPAISFEFFPPKSEAMEERLWDSISRLAPLDPLYVSVTYGAGGS
TRDRTHRTVRRIVEETALKPAAHLTCVDARCEEVDEVIRDYWAAGVRHIVALRGDPPSGV
GDRYEPFDGGYANAAELAAGIRAVGDFEVSVGCYPEKHPESASFDHDIDLLKAKIDNGAT
RAITQFFFDADVYFRYLDRVRKAGIDIPIVPGIMMQSNFAGLVRMAGLCGASIPARLFDL
FDGLESDPGTRELLTANVVADLCHDLCDQGVDQLHFYTLNRAELALATCRLLGVRPVEMA
A
>A0A497SW34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aenigmarchaeota archaeon|TrEMBL
MELKGSPKFLTGCSIKPAKNEIALEAELELTQKKVKEGAQFLVTPPVFNINAFTYFMEKA
KGLGIPVIATVFLLKSVGVARYISTNVPGPPIPEEMISRLRKAPDRINECINIAGELITS
LKELCQGVQLVTMGWENRLPAILDAAKI
>A0A379JHZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia otitidiscaviarum|TrEMBL
MQHLGPRPDGSIPFSVEFNPPRDAAGEARLWRAAREFERLHPAFVSMTYGAGGSTRDRTI
RVTGQLARETTLLTVAHLTAVDHSVAELRSIVGAYADCGIRNLLVLRGDPPGDPLGEWVK
HPDGVEYAEELVRMVRELGDFHVGVASFPQGHPRSVDLDSDTRFLLAKLRAGAEYSITQM
FFDVEHYLRLRDRAVAADPEQGAKPIIPELMPITSLRTVQRAEELSGRPLPAAVMERLRK
AAGDGPEENREAVRAAGIEIATEMAQRLIDEGAPCLHFITLNFAKATGEVLSNLGYTVTP
APVRA
>A0A3D9BI65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Chryseobacterium massiliae|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICASIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHGSAMELVHQINDLGRGKYLHNQDEICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEDLINEVENAKNNEAVKQIGIEWAIAQCRELLEFGVPVL
HFYSMGKSDNIKKVAGALF
>A0A2U1S4D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division NC10 bacterium|TrEMBL
MKIADIYSNGRFGLSFEIFPPKTEAGEAQLLSALETLIVYRRPSFVSCTYGAAGSTREQT
LELTVKIREACGVTTASHRTCVGSTVEEIRLWLKGATDLGIENIVALRGDPPKGEPEFKK
PEGGFAYANELVTLIRQEFPHFSVAVAGYPETHQEAPSPAVDLANLKRKVDAGADAVITQ
LFYDNRDFFDFRRRYTEAGITAPLIPGILPVVNLNQIQRITSMCGAKIPISFLKELEAYR
EDSQGQIDVGVRYAIRQCRELLDAGIPGLHFYLLNKAEATLRILQALDLPR
>A0A1N7QSK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium ureilyticum|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVKKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAITQCRELLDFGVPVL
HFYSMGKSDNIKKIAGELF
>A0A4Q1D7T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Filimonas effusa|TrEMBL
MKITAHLAKATDTLLSFEVLPPLKGKSISSIYDHLDPLMEFKPSWVNVTYHRSESMFKKK
TDGTFEKVEVRKRPGTVGICAAIMNHYKVDAVPHIICGGFNMRETEDALIDLNFLGVHNV
LALRGDAPKNEASFDAEPGGHNYAIDLLKQITNLNAGIYLDEDILNGGKTDFCIGVAGYP
EKHFEAPNPEIDLRYLKEKVDAGAHYIMTQMFFDNQKFFAFVDACRKAGINVPIIPGLKP
LTSKKQLSVLPRVFHVDIPSTLSNDIMKCKSDAECEQVGTEWLIEQSKELRKFGVPVLHY
YTLGKPKVIRNVVEQVF
>A0A4R2P464|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum skagerrakense|TrEMBL
MKVTEHIEQSKGKTRFSFEILPPLKGQNIDSIFNNIDPLMEFNPPFIDVTYHREEYVYKE
LENGLLQKQVVKKRPGTVGICAAIQNKYNVDAIPHVLCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKSEIYFKPEREGHQYASDLVDQIECLNQGKYLDEELQNTSPTDFCVGVAGY
PEKHMEAPSLDSDIHFLKKKIKKGADYIVTQMFFDNQKYFEFVDKCRAEGITVPIIPGLK
PISTKKQLNLIPHRFKVDLPDELIMAVVKCKDNKQVREVGIEWCINQSKELISKGVPFLH
YYSMGKSDNIKAIASEIF
>A0A3D8IG32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter didelphidarum|TrEMBL
MFTSPHIVEDFITKIYSKKCITYELCPEKSGSVVKLVEKVQKVKLHDMQSPHNSIDGFVC
TDSPLAILKQNSGLASIKLQQKLHKPLICTISMRDRNSLALSAEIMGLNDFDIRIFLALS
GDPIKLGDQPQAKAIFEGNSLRILEILSCLNQAKDLNENPIKEPLKKLYGFSVINSYAKK
YEILKNKMESKIKAGALALFTQPIYDVNVTNMLLEWLEEFNERHNSRCILMQGFFPVVRY
KSAVFLHDKLPGVFIPTKWIEVLEKAQTKGVEYERQKGMEMSIELFNILYKNYPKIHFMN
NNNTIHAKKILDTI
>A0A1Q7QHR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium 13_1_40CM_2_70_6|TrEMBL
MARITDLLLAGRTFSFEFFPPKDAEEQQLLTRTIADLQPLRPSFVSVTYRGGRISRERTT
RVVVDLLRTTELTPMPHLTCVAHPRSELGDIISAFRAAGLENLLALGGDPLPAEEQYKEL
EYAWELVDLGRSLGFRSIGVAAHPAGHPRSPDLTSDRRHLAFKMNLADFAITQFFFKVEE
YERLREDVAALGVAKPILAGIMPITSLTSVQRMAQLSGYAVPDDVVRRIEAGGDDRAEIR
RRGIEVATELCRDLLDAGVPGLHFYTLNFSKATREIYANLGLVKSDGRPDVPEG
>A0A1M5HW29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliifodinibius roseus|TrEMBL
MKVIEHYDRAKEPLISFEIIPPKRGKSVKKVFDALDQVMKYNPPFIDVTYHAAESHYEEL
SDGTIKRHIKRKRPGTIGLCAAILHKYGVDPVPHLICEGFTKEETEDALIELNYLGIDNV
LTIRGDAADDPIPRYKNGTFNKYAVDLVKQVKDMNKGKYLEDIVNAQKTDFCVGVAGYPE
KHFEAPNLDFDIQMLKNKVDEGGDYIVTQMFFDNDAFFRFVRKCREAGIECPIVPGLKVL
TREQHLNFLPKYFHLNIPEDLSDEVQANPTHAREIGIEWAARQCTELLEGGVPGIHFYIM
GDPTPALDAVDKLSLGHSVVKK
>A0A1X4XZH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurella amilsii|TrEMBL
MSFASLIGKKKLLTIEFNPPKNTDISKFILELEQFRGIIDAINVTDSPMAKPRMNSIVSS
NFIKHISEPIFNLTCRDKNKIALKSDLLAASALGLKNILAITGDPTKDSNSVYKINVFEL
IELIQSLNEQFNINFFIGCASDIPKLNTIFSIKARLKRKTDLGVKFVITQPVFSQDDLER
FLEATSQMSIYKIIGIMPILSYKSAMYLNNNVKGVNIPKSILSKFENASKEDSRLIAFDL
HEKLLNDISNLLPYIEGLHIMKLDYEIVNLTKKYLEV
>C7LX76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomicrobium baculatum (strain DSM 4028 / VKM B-1378 / X)|TrEMBL
MKKHIMTVLGERVVVADGAMGSLLFDRGVDSSSCYDALNLTEPALVQSIHKAYADAGAEI
LETNTFGANRVKLGRYDLAHTTREINLRGAELARGEAGAGRWVAGAMGPLGRMGLDAVSQ
EEMEDVFSQQALALVEGGVDFIMLETFASLSLLLTALRGVKACVSVPVAAQMVFTQRGRT
HSGHTARECFDALIRAGADVVGLNCGIGPKNALEVVQGLGPVTVPLSVLPNAGFPESSGD
RLIYASSPEYFARRTAACATYGARLLGGCCGTAPEHIAALVRALDAGSPEARIISVSPDE
IKTQTAAPTRLSRRLGEGKVILVELDPPKHLDVEPVLAAAEALSAAGVDAITIAENPLAV
PRLSNIVLAGMVRARTGVDVVVHMTGRDRNLVGMQSTIMGLAASKLHNVLAVTGDPPSAG
SAERVSGVYDLRSLELMELLAGFNQGRNHYGDSMRLPVNFCIGGAFNPNTRNMALQVGRM
EKKMAAGASYFLTQPVYSRARVDEILAATRHIKAPIVLGIMPLASSRNAEFLHNEFPGIE
IPLETRERMARAGDHGQEEGVDIAWELLEYAWSHFAGVYIIPPFNRHGMALELMRRLGR
>A0A7X9YQA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A7W5FPU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus phyllosphaerae|TrEMBL
MLKESIESKKTGIITYGMTPPKKSHTPEKIAEISQKQVERLKKVDIDALILYDVQEEADR
MEEERPFPYMEMLDPETYSEQYLHELDIPKIIYRCVGKYSGPELTDWIKKSSAKDRFSVF
VGASSSQQQVTLGLPEAYNLCQQHNGNLTFGGVVIPERHMKKNDEHVRVVNKMKQGCNFF
VSQATYNIEASKNFLSDYYHYCNENEIEMVPILFNLAPCGSTKTLEFMKWLGISIPRWLE
NELKYSTDVLDKSIRLTNKIFEELLDFGIEKGIPVGCSVESVSTRKVEIEASIQMVSDIK
AMIEKRRLVGSAR
>A0A7C2EJ76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ammonifex degensii|TrEMBL
YARQFPVKILAGIILLTSVGMAKYMNANIPGIFVPQHLIDELASAGKGRALEKGIEIAGR
MIATLKKEKLCDGVHIMAIGKEEVVLDILAAAGI
>A0A7V1BKP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopseudomonas xinjiangensis|TrEMBL
MNNPNKPVISFEFFPTKTDAGHEKLIAAAHVMAAEKPEFFSVTYGAGGSTRDRTLNTVLQ
LDQEVKVPTAPHLSCVGDSKADLRSLLQQYRASGIKRIVALRGDLPSGMGQASGELRYAN
ELVEFIRDETGDHFTIEVAAYPEAHPQARHFEADLENFVRKAQAGADSAITQYFFNADCY
FNFVDRVRKAGVDIPVIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASISS
FGTDVISRMCERLLEGGAPGLHFYTLNQAEPSLAVWRNLHASSHSN
>A0A2G3DZB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agathobacter ruminis|TrEMBL
MQEIREYIKEHNLLFDGGFGTYYTQRFQTDIQNCEKENLIHPQQVKSVHSAYIEAGARAI
KTNTFHCFDQDRQMQEQVIRRAYAIAKEAVEESGEDVYIFADFGPAQGETNEQCEAYFTS
AIDVFLEEGATNFLFETQSANNGLLPAIAYLKERQPNAFVLVSFGVMPDGYSAEGCYYQS
LMREFLESGLVDYIGLNCVSSPKHLGMLVERLSVEERRRMSLMPNAGYPVVRGFRTFFDG
SVDYYAKQMRILAEKGIPILGGCCGTTPKHIAGVARELAQMEQYTIADELEANQKQQVRT
RVEVAPDNRLLAKLKSGKKVIAVEFDSPKNADVSKFMEAAAQLQQSGIDAMTIADCPIAV
ARMDSTLLACKVKRELDLDIIPHMTCRDRNTNATKALLLGAHAEGVRNVLFITGDPIPTA
QRDEVKQVYQFNSRKMMGYVNSLNDELFAEAPMAMFGALNVNAVNFDVELKRAQQKMQEG
CIGFLTQPVMTEESMENIRLARKTLEGAYILGGIIPVVSERNARFMNEEINGITIPQEMI
DAYVGADRKEGERLGITFSCRIAEKIAPFVDGFYFMTPFGRVSLISQIIQTILLKNCD
>M6AK30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira sp. P2653|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPDGDLKLMETVKELALLDPDFVTVTYGAGGSTRDK
TVQILSEISKRYSFPTVSHFTCVGANQDQIFKALEEIRSSEIVNLMALRGDPPKGEGKFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPDAKSLEEDVENLKRKVDAGTDFLVS
QLFFVNSIFENFLNLVRKAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A5N6J7A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus minisclerotigenes|TrEMBL
MGMFPFPLIGGPVKLRPKPFPPRWISPQSSLFNYLARNFAGTDSGIKMEKITDKIAALPP
DANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGTTAQRSLELAEICQR
QLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNRDF
TFAVDLVRYIRQKHGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTQAGADFIMT
QLTYDIEAYTRFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVQIPPQILSK
LEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLRGFHFYTLNLEKTVSFILERCDLIPP
YSEDFDAIEEGGDISAMDGAQLRSLTRRRASSINSLPHNRVIVDKLHASEVSSKASVSHE
APATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSL
HVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRSEL
LQLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPL
LQKHGHEKLAWFAANVKGDFESSLPAQTSDADPIEMNPDNVNCVTWGVFRGKEIVTPTII
EEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNDIKDDVWLVCVVGQDFGAGTEMGSED
EEDEKKFMWRVLLNAKK
>A0A1F8LVI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_46_14|TrEMBL
MPVSFKEKLDSGKFVITSEIAPPKGTNLEQMHHHIEMLKDKVDALNVTDHQSSVMRFPSI
GGCMAIREHDGEAILQMTCRDRNRMSLQAELMLAYTRGIKNVLCLTGDAIPVGDHKEAKG
VFDLDSVQLLRTIRTMESGYDLGGNQLDGVVEFCSGAIVTPEANPLEPQLMKFEKKVESG
AVFFQTQAVYDLDNFTRFMKYARRFPVKILAGIVLLSSARMAKYMTENVPGIFVPQNLID
ELSSAPKGEALAKGIEIAGRMIATLKKESICDGVHIMAIGKEEVVPDILAAAGM
>A0A373YA13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF16-50|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKKRVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A263DEB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. MH-G8|TrEMBL
MHGVKVTQRIRGDRPVFSVEFFPPKDEAGEADLWRAIRRLESLDPAFVSVTYGAGGSSRD
RTIRTTARIATDTTLVPMAHLTAVSHSVAELRQVIGAYAAAGIPNVLAVRGDPPGDPLGE
WIAHPEGLNYADELVQLVRRLGDFCVGVAAFPYGHPRSPSPEDDLARLVAKVRAGADFAI
SQLFLEPEGFLRLRDRMAAAGCDVPLLPGIMPLTTVRTLRRGPELSGAPLPPGLVERMER
YADDPAAFRAAGMDVTAEMCSRLLEEGVCGLHFYTLNRSTATVELVQRLGLGARRAEPAG
AVPVSG
>A0A1B8QKD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella atlantae|TrEMBL
MTTPFSIEFFPPKTDDAATKLLHTFAELNALQPEYFSVTYGAGGSTRARTLGIVKTLSEA
SATPIAPHLSCIGDGKAEIAESLDTYTALGISKIVALRGDLPSGQVGFGELPYAVNLVQF
IREYAGDRFEIEVAAYPEMHPQARNFASDIDNLVAKYRAGASAAITQFFYNPDSYLYLRD
ALAKRGVQPEDFALKAGIMPITNASNLIRFADACGADIPRYIRRQLADFGDDRAAIRAFG
FDVVMRLCERLITEGVPALHFYSMNQVNPTKALIEALDLRQAVDLTFNQTTKSIKV
>A0A1I6LGP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas jatrophae|TrEMBL
MTFTLTQLEEARRALDAPLYADLAGDAEVSFEFFPPKTAKMEETLWSAVETLAPLAPRFV
SVTYGAGGSTRERTHATVARIAAETNVPAAAHLTCVEASKGEIAEVADAYWQAGVRHIVA
LRGDPPREGERFQPHADGYRSAAELVEGLLKLHPFEISVAAYPEMHPEADCADTDVLNLK
RKLDAGAAQAITQFFFSPDAYFRFRDRAAAAGITADIVPGILPVSNVAQTRKFAGMCGAA
IPPWMDRLFEGLDDHPATRQLVAATVAAEMCRKLYAGGVRQFHFYTLNRAELAYAICHLL
GKRPVRAAAPLEVAA
>A0A8J3PE48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catellatospora methionotrophica|TrEMBL
MRELLVSGEPTFSFEFFPPKTADGERLLWQSIRELESLQPSFVSITYGAGGSTRDTTVQL
TERIATETTLLPLGHLTAVNHSVGELRNVIGHYSDAGVRNMLALRGDPPGSDPQADWVAH
PQGLHYAEELVRLLKDSGDYCVGVAAFPEKHPRSADFESDVHHFIRKCRAGADYAITQFF
FDWQDWARLRDATAAAGCDVPIIPGVMPVTNVSQIERMAQLSGAAFPPDLAQRLRAVADD
PQAVRAIGVEVATELSTKLLAEGAPGLHFITLNRSTATREVWQRLRVGATV
>A0A0K1E0M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrobaculum sp. WP30|TrEMBL
MEIIAEVTPVRDRTKLLKKLETLKPLVNRIDIPEAPGGKPTAHALAVGALVKQMGFEPIV
HIRLLDVNKTGLKSLLGGAYLLDIKDVVVLQGDPPAEGRPVGEVSTEEAVEEAKKMGLRA
GALLSLRRDHRKRVETLRADFYLALHLTDAKQLEGLPPIVYPYVMVRTSNNSELIDRLRQ
TAVEPHEALALVEALEGAAPGAVISVPGDFDALVGLLKQIKTRRG
>M0JIH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula vallismortis ATCC 29715|TrEMBL
MALGTRAVSDSQGVQTLLTSARFELMPFESFDEEITHLPNDATIAITTSPQLGIEKTVEK
TEQAAAMGYDVVPHVAARYVEDWEQLEAIAERLEQAGITDIFVPGGDREEPAGEYESALD
MLEALAETEYTFEEVGITGYPEGHDFIDDETLAESMAQKAPYATYIVTQLCYDPDAVLEW
VEDIRGRGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDNEYNIRGVHIYTFNQTPDTEQWRHKRLDS
>A0A6L3C4I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. BB081|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6H1P9Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia megaterium|TrEMBL
MSLLEKLKNQILIADGAMGTLLYSYGVDSCSEELNLSQPEQIQNIHQAYIDAGADVIQTN
SYAANYLKLQRYGLEDSVKEINSAAVRHAKQAAQNNAYVLGTMGGNRGIKTNSITIEEIK
RSFREQLYCLLLEGVDGILLETFYDLEELETILTIARKETKIPIIAQVSLQEPGFLQDRT
PVNDALKRLEGLGADVVGLNCRLGPHHMLLALEQIELPKHAYLSAYPNASLPTYTDGKFH
YEGDPDYFRNSAKAFRNQGVRLLGGCCGTTPEHIKAYASELKNSVPITEKVVKLEPKKII
VESLAPKREFTPLQELVKERPSVIVELDPPRKLDTTKFFQGAKALKEAGIDSITLADNSL
ATVRISNESLGYLLKQDLGMRPLIHIACRDRNIIGLQSHLMGLHTLGMNDVLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTDFSIAAAFNPNVRSLEKAVK
RLEKKVHYGADYFISQPVFSEEKLLEVYEHTKHLDAPIYIGLMPLISSKNAEFLHNEVPG
IKIADTIRTRMAQLGDDPIQAAREGIAITKSLIDTALDLFNGIYLITPFLRYELTAELAL
YTRQRASELRRSTYAENTIY
>A0A850SX87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvularculaceae bacterium|TrEMBL
MSDLHVSFEFFPPKSEAVQQRLWAAVEKLKPLAPDFMSVTYGAGGSTRERTHETVARIIK
DAGVPVAAHLTCVAATKAEVDQVLRDYWAEGVRHIVALRGDPPGGPGERYIPHPGGYANA
AELAAGARKIAGFEISVGCYPEKHPDSPSAAADIDMLKRKVDAGAARGITQFFYDNDVYY
RYVDRVRAAGIDIPIVPGIMAITNFASVRKMADTIGATIPGRLVKLFQNLDEDPQTRQLI
AATVAAEQCLALAEQGVKHFHFYTLNRDDLAYALCTMLGVRPTAQAKSAGAAA
>A0A6V8PT89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hakubanella thermoalkaliphilus|TrEMBL
MKSGSNLEKVLSSGHFAVTAELGPPKSCDPEVVEKKAEILKGFADAVNITDNQTAIVRTS
SIAAGVIVARKGLEPVVQMTCRDRNRIAIQSDLLGAAALGIKNLLCLTGDHQSFGNHPQA
RGVFDLDAIQLIDMVRRMRDEKKFQCGEEMSVEPRFFIGAAANPFADPFEFRVIRLAKKV
TAGAEFIQTQLIYNVEKFARWMKMVREMGLHEKTYILAGVGPIKSAGAARYMKNKVAGMD
VPGEIVERLQAASDPKAEGIKLCLDIIEQVRAIEGVAGIHIMAIEWESAVPEIAERAGLL
PRPQID
>N9NTB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 1847|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GQGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A5P2BP69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces venezuelae|TrEMBL
MTALRDIVEEDAPSFSFEFFPPKTDAAARTLWHTIRRVETLAPAFVSVTYGAGGSSRDRT
VEVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLAVRGDPPGDPGAPWI
PHPDGFTHAHQLVRLVKESGAFSVGVAAFPERHPRSADWDSDIRHFVAKCRAGADYAITQ
MFFHVEDYLRLRDKVAAAGCTTPIIPEIMPATDVRQIGRFAALSGAAFPEHLAHRLEAAR
HDPAQGHRIGVEYATAMAQRLLAEGAPGLHYITLNRSTATLEIHRNLHTPTTPASPAVPG
TIGEPHGLAAPR
>A0A2M7CAH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG03_land_8_20_14_0_80_45_14|TrEMBL
MSLQENFRNKRFIVTSEIQPPIGTGVQDLLRNVERIRGRVDALTVPELKIEGLVTDTMGT
CRALKDQKFDPILQTTCREKNRLEIQEHLLRASESGVENILAFTEDYRITGDSLQEIMFF
HVDSGKLFSVIESLHQGCDISGKEVRVKPQFFVGSGIDSSWGKKVPDLELKELEALAGLG
TQYFLTTPIFDLDSFHEFMKKVGPIRIPVVAEVILVRSAEMGLFLNKHVKPGMVPNHIIE
KLAKAPDKEKASIEIVSDLVKGLRDICQGVHFIPIGAEDRISKYLDAAKLSSL
>A0A5P2A7F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces venezuelae|TrEMBL
MSPTFSFEFFPPKSPRGERTLWEAIRRVEALSPDFVSVTYGAGGSSRDRTIEVTKRIAAE
TTLRPVAHLTAVGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRGAWTPHPRGFTYAH
ELVELVRSLGEFRIGVAAFPEGHPRSADPAEDLAHFVAKCRAGADYAITQMFFDPEDYLR
LRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAKDDPAAAYRVG
VEHATGMGLRLLDEGAPGLHYITLNKSTAALEIHRTVMSARSVVHV
>E4TDS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Riemerella anatipestifer (strain ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014)|TrEMBL
MKVTEHIKKSEGKTLFSFEILPPLKGQNIQCIFDAIDPLIEFNPSFIDVTYHREEYEYVE
VRDGLLEKRVVRKRPGTVGICAAIQNKYKVDAIPHILCGGFNREDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKNGHTYASDLVKQIQDMNKGIYLDTSLEKAAPTNFSVGVAGY
PEKHMEAASFSQDIGHLKKKVEAGADYIVTQMFFDNQKYFDFVDRCRSEGIGVPIIPGLK
PIATKSQLSLIPHRFKVDLPDDLVTAITKANNNNEAKEIGVEWCIEQSKDLMKNGVPILH
YYSMGKSESVRKIAEAIF
>A0A410Q534|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caproiciproducens sp. NJN-50|TrEMBL
MRTSELFQRKTVFSFEVFPPKKTASIDTIYNALQKMRGLSPDFISVTYGAAGSAGDLTVK
IASDIRTRYGLESVAHLPCINFTRENVLEVLKTLKQSGIENILALRGDISPDSAPQTDFK
HASDLIAFIKENGNFNVIGACYPEGHPESGGLVRDIQNLKIKVDAGTDQLISQLFFDNSC
FYSFLERTEIAGIHVPIQAGIMPVTNKKQIERMVSLCGAALPKKFETIMEKYGSDPAAMR
DAGIAYAIDQIVDLIAQGVDGIHLYTMNNSYVASKISEAVSSLLKANQISA
>A0A4R9ATX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Hz16|TrEMBL
MTEIGISACDVRPAFSFEVYPPKSTVAAAALTRTIDHLAAAGPEFISVTYGANGSSRRSS
LDVLRYIKDHTTVDAMAHLTCVGSSHAEASRLIREFLDAGIRSFLAVRGDAPQGAVEGDS
TFLGDLHSAGELVQLIHRVQTERVPYTETVIPGLPGARGVKTERSKVRIGVAAFPNGHPS
SRSVSQDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLFPILPGIMPVTSPN
RLRRIVQLSGEKLPAELSIELEVEPTEEGQRQIGVDYAVRLGRDVLAGGAPGLHLYAFNQ
HDTVLEVLEGCGALAVPVAMP
>A0A1W2B4Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moheibacter sediminis|TrEMBL
MKVTEHIKNANGKTQFSFEILPPLKGQNIQSIFDHIDPLMEFNPPFIDVTYHREEYIYKE
QENGLLKKHIVKKRPGTVGICAAIQNKYKVDAIPHILCGGFTKEDTENFLIDLDFLGIEN
VMALRGDAVKNETYFRPEKEGNAYAGDLVAQIQSMNQGIYLDDEMQNPCPTNFCIGVAGY
PEKHMEAPNLDNDLHFLKKKIQNGATYIVTQMFFDNQKFFDFVEKCRKEGIEVPIIPGLK
PITTKSQINMIPHRFHIDLPDELLIEVIKCKDNKAVQEVGVEWAIQQSKELQQAGIPVLH
YYSMGKSEAVKAIAKEIF
>A0A843B300|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccus sp|TrEMBL
MRSGSNLERVLESGRFAVTSEIGPPKSASAEPVRRKVAEMKGWADAMNLTDNQTAIVRLS
SLASSVVCLQEGAEPVMQMTCRDRNRIAMQSDLLGAAALGIKNVLCISGDHQTFGNQREA
KNVYDLDPIQQLMVFSRMRDLGQVWGGDPLEERPQVFLGAAANPFADPFEFRVARLAKKV
SAGADFIQTQAIFDLDRFERFMSMVRERGLDRRTHILAGVVPLRSANAARYMKTKVSGMS
VPDEIVDRMKDAADPKKEGIRICVETIERLKEMPGVHGVHIMAIGWEQMVPAIVRESGLS
PRP
>A0A7Y4S4P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium|TrEMBL
MHSQANHPQLFSFEFYPPKSEEGAANLQVVHSKLAALKPDFFSVTFGAGGSTRDKTFQTV
VEIQTKGIAAAPHLSCVASTKDNIRAILKDYRDEGISKIVALRGDLPSGMMSAGEFRYAN
ELVEFIRQETGNYFQIHVAAYPEVHPQAVNGREDFKNFKRKVDAGANAAITQYFYNAESY
FYFVDACEKNGIDIPIVPGIMPITQYSQLFRFSEMCGADIPRWLRKRLEDFGDDRSSIQA
FGLDVVTNLCQRLLDNNAPGLHFYTMNQSAPTLAILENISL
>A0A7D4A6P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura verrucosospora|TrEMBL
MRPVRPDRPPTVRELLASGERSFSFEFFPPKTDKGARNLWRTIRELEPLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPEGVEYAAELVRMIRSYGDFSVGVAAFPYKHPRSPDVESDTRYFVEKCRA
GADYAITQMFFRAEDYLRLRDRVAATGCATPIIPGIMPVTKYSTIERSEQLSGAPFPPEV
RARFDAVADDPDAVRRLGIEHAAELCRDLLDEGAPGIHFITFNQSTATREVYGLLESGGY
GAKGSVPPMTA
>A0A8G1LZV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deefgea sp. D13|TrEMBL
MPNSLHTKIAQRQSGILLYGITPPKANNTPEKIAEIAALQIERIAPLGLDGLVLYDIQDE
ADRTDATRPFPFMATLDPLVYSRDYLAALDMAKIVYRCVGKYSPEQFGADLLAMNDGVSV
FVGAASRQQQVSLTVAQAYALRREVNPHLLVGGVAIPERHLVKNDEHLRVAHKVTEGCSF
FVTQCVYNVEAAKNFLSDYYYACQQTGTAMVPIIFTITPCGSVKTLEFMKWLGISIPKWL
ENDLIHSGDILAKSLDVCKGIFAELLQYAAEKGIPVGCNIESVAIRKDEIEASLQLVRDV
QQMFLATRA
>A0A835X898|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon|TrEMBL
MTIIYEVNPPKLPKDKTLSDAERENLLEKLNERMSEISKSCDGVHVTDSVLGTKRISPLV
ASKLIKKNFPDIKITISVRVRDNDLAEIEKIVNDAITLGVNGVLILKGDASPDNPKDSGL
IPSQVVKHLKELELDKKIDLFLSLPANPDFKKIQKKIDAKPTGFITQVVESVDQVSNLVS
LLKPHGFKIIPIVLFPSDKNLKSAQFLKLDWSNYEENVFDFIKKIHGLTTNVLITSPNDF
NGVQKTLTKLAI
>A0A0S8G4X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillales bacterium SM23_46|TrEMBL
MFENRFRESLLNPDRLTVVLEFTCPAGQKPTRLLKFLADFESEQPNWPDTEIAGITVTHN
PSGVVTASPSDVYAHVLARRTAGGMRGLSFIPHVSAKGMNSAEIETFLRGLASHGIENCF
TITGDQPLLGRPVFEFDSLNLLLFLRKMNADARVATGAGAQANVFFAGAAAGLAKYEEGT
CRQQMFKVEKKVRYGHAGFLITNLIYDPRKVEDFFRFLRERDINVPVVGNVFYLTNAAAR
RMRHESLPGCFVSEALYEQVASESRDEWVERCAQLVAMWRDLGASGVDLGNVEDLALATE
IIERARAIGSSWREKRDNLTFAPARDNLFYLYDETGQPTPGRRPTVPLRRRLLNQTHQRF
FEPGALGYKMMRKLLKHSRSIDEGKGFTYETFYLLETVMKRVMAKCRACGDCYLPENFFV
CLMGECTKGLTNVPCADSTADGQCGIDDSKPCAGRLVYDAARFFTSDVEALRELVNPPKD
PELLNTSSFRNFFLMKDHHRRNPLVIVGELIHTTIPKVRKAFDLIKRSDADFAPDNPGVE
FVRAAVESQILKGCDYLDCNVDDAGEGNVELASRLMRGAVRLIFEQGEGPPPCLDSSDVA
VLRAGLEEYYRLAASDAXXXXPAADQFGQRREPRQVLGSPFGRPLQRRLHADGVIAFAQG
NRPIRDTRANARKCAGFLPRSDATRFPARTDLLRHNRHATGRGVLVLRPPGIQPLQFRSL
TPNYAERGDERRRDNSRHQQFGSRFPPRTENRHSARLCPSGDGPRPDRRHCGCGERLRHQ
AARGR
>A0A5N9EGK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MLLSNFRRPVSSQVNSGPDHYKTENNLNIRDILPNSRTISFEFFPPRAADGIPGVLETLE
QLKAYAPHFVSVTYGAGGSTRAFTEEITIKAKNSGQVEVMAHLTCVGQTVDELDGVLQRL
EAASIDNVIALRGDPPRGETEFVPVEGGFGHASDLVKYIRGNYSFGIAAACYPEGHAESV
DPETDLEYAKLKVENGADFLITQLFYHNDDFFRFVEKAQASGIDVPIIPGVLPVLSASQI
RRFTALCGSKIPPDLDAQLVKYAEDDDAAREMGVEYATRQVEGLWAAGVPGVHFYVLNRS
YSISKILD
>A0A1I6NWQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora flava|TrEMBL
MTSDLRRSLDRMRYEVLPVGEARVDLLAPGTTVTVTASPSKGLEPTLARTERLAADGFHA
VPHLAARSIRDDAHLATALDRLDAAGVDEVFVIAGDASRPLGEFADSLELLRAMERLGRL
PGRIGIAGYPERHAFIPDDSTARAITAKARYADYVVSQITFDPRTIIDWADDLRFRGVDL
PVWVGVPGVVDAHRLLRIALKIGLGESTRFLRKQYGAVSKMLARYTPEELFEELQPRLAD
PDSPIAGWHLFTFNEITRTVRWRDDLAARLSGRADRPA
>A0A455UZJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas axialensis|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAARNPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSERLSCATYWRSTGKRASIA
>A0A1Q3ELX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentinula edodes|TrEMBL
MKLTDKILAYSSPHPFYTFEFFPPRTDQGFENLLPRIVRMSNLNPLAVSVTWGAGGNTKD
TSLNLAELTQSEYRQDTILHLTCTNMEKGKVDEALRVAKECGIQNILALRGDPPRGKEEW
IAIDPRFQHALDLVTYIRSHPDFSSYFCIGVAAYPEGHPDHLVDEETELSLLKEKVDAGA
DFIITQLFYDEDQFISWFRKVREKGITLPIIPGLMPIQTYQSFVRLTKLTGSKVPAQVMS
DVDAIKHNDQLVKNYGVELAVKMIRRITTETDVSGVHFCTLNLEKSVQRVLESLRWIGYS
PQIVPNKLIEEPTTENLPSGTITPVSAANVATLGLYNMPPTETEVGSGELNKADSWDDFP
NGRWGDSKSPAYGVQGPWGNNDAINQVTISQWGNPQSLDDLTALFLKYLHSDIDTTPFSS
DPILDESKLILPHLRKLTERGWWTVGSQPAVDGIDSSDPVVGWGPRNGYVFQKSFVEFFC
TEEDVNMIEKKVAEKGDGWVHYYAANSKGDCRTNVPDDGRNAVTWGVFSGQELIQTTIIE
RQSFLAWKEEAFSIWLDWASFYRPDSLERKLLESVHNERFLVNIIHHDFKVEEALWTFIF
DA
>A0A5N9G4G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MKIRQILESKRTLSFEFFPPADDAGVKRLFNTIYALKAYDPDFVSITYGAGGSTQAVTVE
MAVRAQRETGLTVMAHITCAAQTAEFVDSALSRLATEGIENLIALRGDPPKGKSKFTAVE
GGYTHASDLISHVKRKFQFGVAAAGYPEGHPESIDLESDMKFTRLKIDLGAEFLITQLFY
DNDDYYAFVDRAQKAGVNVPIIPGLMPVLSASQIRRITGMCGASIPKELDELLDRHGDDN
RAVRQIGIEHTTRQASDLLDSGVPGVHFYVLNRRFSMTRILENLRESGHTTAFS
>A0A3L6NYI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. cepae|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDRIKAIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASSELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A349ZZ44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MKITEHLAAAAGKTLFSLEVVPPHKGTGIGDLYKNLDPLMEFNPPFVDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYGVDTVPHVLCGGFTPAETEYLLIDCMYLGIEN
VMALRGDAMKGHQHFEASNGGHSYASELVTQIRELGGGKFLHSEEAAGDNTKFCIGVAGY
PEKHIEAPSLQFDLERLKQKVEAGADYVVSQMFFDNQKYFEFVAAAREAGITVPILPGIK
PVAVKTHLQMLPKVFKIDLPEPLINAMQEAKDNTAVRQVGIEWAIAQCRELMQAGVPVLH
FYSMGKSDNIREIARALF
>A0A6L6X909|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces typhae|TrEMBL
MTNGKPVFPWGPGPSFSFEFFPPADDKGRRTLWRALREVEALSPAFVSVTYGAGGSSRDG
TIGLSARIAAGTTMRPVTHLAAVGHSKDELRHVLSRLADAGVRDILALRGDPPADPRGPW
TRHPEGVEYAAELVSLIKEWGDFTVGVAAFPERHPRSPDWDSDVRHFVAKCRAGADYAIT
QMFFHVDDYLRLRDRVAAAGCETPIIPEIMPATDVRQISRFAELSNAAFPEDLAHRLEAA
RDDPAEGRRIGVGFATAMAARLLAEGAPGLHYCTLNRPRAALDIHRDVLGSATRAVPSRR
L
>A0A6L5X8H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sodaliphilus pleomorphus|TrEMBL
MTKIIDIINGSHKPFASFEIVPPLKGNDAARLYAAIEPLMQFAPPFINVTCHRDEVEYID
NGDGTYSRLTLAKRPSTLAITAAIMSHFDVEVVPHVICGGASKTKIESELLDLNFMGIDN
VVALRGDAMTGQKFFQPEPDGFAHSDELVAMIARLNRGEYLDPNVKNGISTDFCVGVGAY
PEKHYEAANLETDIAHLKAKVDAGAHYVITQMFFDNSRYYDFVRRCRVAGITVPVIPGLK
PLSTLRQLELLPRSFHIDLPHDLVTAILQAPDPEAVYEVGIEWCIAQSRDLLAHGVPAIH
YYTMGKARNVTAVVQAVF
>A0A1F1L3M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. HMSC19A10|TrEMBL
MIKEFLNNNILICDGAMGTYYSEKTGNDISYCEFGNLNDKNTIRRIHEEYIEAGAKLIRT
NTFSANSKELGVSRKTLKDIIESGIEIAKEAVYNKEVFIGASIGPIRENGADENFVEVLE
EYKFIVDCFLDNNINVFIFETLSNLDYLEEVSTYIKNKKPESFILTQFAVKPDGFTRDGY
SVSKIVGEVKKINTIDSYGFNCGSGPTHALELIKKIDIGDDIVSSLPNAGFPEIIHERTV
YPNNPVYFARKVKEIKKLGVSIIGGCCGTNPSYISKLRDTIDNKPEPGDKIKRYEHETYN
EKNIIKNTFKEKVKNGDFVIAVELSAPVDTDINKIMTGAKVCKDNNIDIVTVPDSPMSKV
RADSVVMSSKIKREIGIEAMPHMCCRDKNTNAIRSSLIGGHIEEIRNILAITGDPISDAS
RIETKSVFNLNSFKLIELINDMNNEVFTSDDIFIGGALNLNVLNKEVEYGRMMKKVERGA
KFFLTQPIYDDSAVEFLKSIKERTDVKILGGILPVVSYRNAMFLNNELPGVTIPQEILNR
FSEDMSREEGQNIGIDIAVSMGKKLKGICDGLYFITPFGRVNMIVDIVNRIKEV
>A0A829X906|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter oxydans NBRC 3293|TrEMBL
MNTNLKRLLSGKLADHPSLCHSDMPVPALSFEVVPPRTDAMEQRLWQCIRRLAPLSPRFV
SVTYGAGGTMQARTQATVLRLKQETTLVPAAHLTCIGATREEIDDIARTYWQSGVRHLLA
LRGDAPAGTDYTPRPGGYAYASDLVAGLRRIADFEISVAAYPETHPAALSPQADIDNLKR
KLDAGATRAITQYFFEASTCLRFLDRCLTAGITAPIVPGIMPVSNYDQIARFSALCGVTV
PAWVTHLFEGTAKNPELCRIAACIVAAEQVRTLQSHGINEFHFSTLNRPDLTCAIAHLLG
VRPASETDS
>A0A356JFS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MPAGTSSQADAFINAFSLEVSAKAMPALRAEAARIRRGTVISIPWLASEDDDARLAAART
VRELGFAPMPHLSARRIGSHAALERFLERATSEAGITRCLLVAGDLATPAGPFADSASII
QTGLLEHSGIKVVGIGGHPEGHPVMSADDRWEVLGRKCQAIEARGMAPLVVTQFAFDADI
VLAWLDALRARGITVPVLVGVPGPASIARLARYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFMDRLLSGLTDAHGPVSPHLFPFGGIAPSLEWVEQYRRSIYSSGG
>A0A368Z0T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium bourgognense|TrEMBL
MSIFRQSRRSDLGSNIRVSFEFFPPKTEVMEERLWETVTRLAPLNPEFVSVTYGAGGTTR
ERTARTIKRILTETDVNAAAHLTCVDATKEEVDTVVREFAAMGVKRFVALRGDPAGGVGA
HYKPTPGGYENGAELVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVEKVRRAGIYIPILPGILPIHNFTQVTNFCSKAGTHIPAWLAERFD
GLDNDPQTHALVSSAVAAEQVLDLVERGIQDFHFYTMNRADLPFAICHLIGIRPGSSDTV
EANLAGAAA
>A0A1M6BH72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribius salinus|TrEMBL
MTAPSISFEFFPPKSLEASFRLWDTIHTLAPLAPEFVSVTYGAGGTTRALTHEAVTTIGK
TTGLRVAAHLTCVNASKEETLEIARSYAAAGVTDLVALRGDMPGGKPFQPHPEGFANSVE
LIEALAATGDFTLRVGAYPDRHPEAATDTADVDWLKRKIDAGADAAITQFFFEADTFFRF
RDRCVAAGIDAPIIPGILPIENWAGVRKFATACGTPIPAWLDDAFETAKRDGREELLSTA
LATEMCSALLDDGVEHLHFYTLNKPQLTRDVVHALGLAPERQLEKVA
>A0A3D2VZG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium|TrEMBL
MSARVQNLIAEAAERMGAPRVSFEFFPPKTEALEIQLWEAIRKLERLNPSFVSVTYGAGG
STRERTHRTVARIVAETSMKPAAHLTCVGATRGEIDDVLRAYWEAGVRHIVALRGDPPGG
VSAAFAPHPDGYSGAADLVAGAKQVADFEISVAVHPEKHPASADWNVEIDNFKRKLAAGA
ARGVSQFFLDADVFLRFRDRLAKAGVAAPVVPGIMPVTNFKGLHKMAAASGASVPGWLAT
LFDGLDDDPETRRLVAAATTAELCARLAAEGVEDFHFYTLNRADLTLAICRIVGVRVAKE
GVAP
>A0A432QZK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocapsa sp|TrEMBL
MLVKDLLDSQKTTFSFEFFPPKEDAAADRLLETIANLMPLEPSYVSVTYGAGGTTRDRTH
DLVVRIKKQTNITVVSHLTCVGSSREEMHGILEKYQDAGIENILALRGDPPKDDVDFVHP
KDGFTYAADLVAYIKKHFPQMCVGVAGFPEGHPSTPNRLQEIDYLKAKVDAGADYIVTQL
FFENRDFYDYCERCELAGIHVPNIAGIMPVSTKSGLIRTAELAGGARIPARLLKAVYRAQ
DNEYVEKVGIHWATEQIRDLIDNGVRGIQFFTLNSSAATQEIYGSLGVRDSSQLR
>A0A0F5FME8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia chinhatensis|TrEMBL
MIDDTLRPSRQTADERPDLQLSFEFFPPKTDAMEERFWESIHKLAPLHPRFVSVTYGAGG
STRERTLRMVSRIKTDTGVAAAAHLTCVGATREEVDEVVRGYQQAGVSSIVALRGDPPEG
VGQPFTPHPDGYQNAADLVGGIRRIGDFDISVAAYPEKHPQSVTWDADIDNLKRKLDAGA
NRAITQMFFSNGDFLRYLERARKAGVTAPIVPGIQPIHSFKQISGFAARCGASIPAWLAE
RFEGLEDDPDTHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRP
>N9QUA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter colistiniresistens|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKTVHQELQLLNPEFFSITYGAGGSTRERTLAAINEFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERITKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A436RWL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.046.02.1.1|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A5WDX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. (strain PRwf-1)|TrEMBL
MNKPRFSFEFFPTKTSEGVEKLCQTFDALNELAPSYFSVTYGAGGTTRNRTLGIVETLQN
RANTPIAPHISCIGDDKVQISELLDFYKSIGINRMVALRGDLPSGQVGMGELPFAVDLVR
HIREHSADHFHIEVAAYPEMHPQAKSFDFDIQNLVNKFNAGANSAITQFFYNAESYLYLR
DALEKRGVDTDKHNLVAGIMPIINASNLIRFADSCGADIPRYIRKQLADYGDDRKAIREF
GFEVVHRLCEILISEGVPALHFYSMNRVEPNKRLVESLGLSSVSTQA
>A0A7X3K6F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. NEAU-DD11|TrEMBL
METPNISIEFFPPKTPEGADKLRVARQKLAELNPKYFSVTFGAGGSTQHGTLSTVLEILA
AGHDAAPHLSCVGGTRESIRAILQEFKDKGIRRLVALRGDLPSGYGGAGELRYASDLVEF
IRQETGDWFHIEVAAYPEMHPQAKSPQDDLQAFARKVQAGANAAITQYFYNPDAYFQFVD
NARKLGVDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWIRLKLASFGDDSASIKAFGLDV
VSGLCEKLLAGGAPGLHFYSMNQAAATTAIWQRITAA
>A0A7K5E0W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polioptila caerulea|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCSQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKDKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRQLLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A850LT49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Helarchaeota archaeon|TrEMBL
MSTNGIYSNLMREIKAKRFVFTGELEPEKTTKLDDLYEGVIYLLDHVVACNVTDNPQSMA
YMSSLVASYIIQLETGMECVYQLRCADRNRIALISDLLGAGALGIKNILALTGDHTSIGD
TSEAKPVFDLDSTQLIYMIRRMIDNGMDLNGNPIHNPPKFHVGAAGNPNSDPLEPEILKI
GRKVRAGAEFIQTQVVFDIEIAEGFLNAIKEYDIPVLVGVFPTKSYGVASYFDKYIPGVS
VPQELLMQLKRVSEITDKKLRKEKYAEINLEYFGDFFKELMKTSAAGIHVMAVGYEKIIR
KLIDRARGKE
>A0A7U3UN96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SN-593|TrEMBL
MRDVLATSGAPLLGAYVVPEAGDRESAAGAAAAVRAAGADLIVTATSGPEHSRYTSTNQS
IDLAAACQKHTGGPALATVTTWSRTVMALQAHLLGGHARGVTRLVCGNGSAPGSGDRAQA
DGRWAVDAVGLIELLRGLNEGVDRYGLRLDTPTHFDIGVRLRAVPTLTAADRGRIRSRIG
AGAHFVVTSPVYTRRALDALLDLVDGAVPVLATVHPLRSLAEARQLRSELPAGCVPDDLV
NRLERAGDGAAEEGGRIAVELAACLAESTRGIILSRADRPEFVAGVRAVLPRPVAG
>A0A3L6M266|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclales bacterium GT-UBC|TrEMBL
MNTEISIEFFPPQTPEGVDKLRTVRAELAKLKPSFFSVTYGAGGSTRERTFAVVKEIAAE
GFDAAPHLSCIGSTRDSIREILNEYKAAGIKRTVALRGDLPSGMAKTGEFRYANELVDFI
RAETGDWFSIEVAAYPEWHPQARSPKDDLDAFVRKVKAGANSAITQYFYNADAYFHFVDA
ARKAGAEVPIIPGIMPIVGFTKLARFSDACGADIPRWMRKKFESFGDDSDSIRAFGLDVV
TELCERLLKGGAPGLHFYSMNQSALTTEICKRLG
>A0A5Q4C1V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum shisoi|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTAMGLSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKDE
YRDTEDSDVDDIEDFVWAVDLVKYIRKNYGDYFCIGVAAYPEGHADESHPQGQSFEHDLA
YLVEKVQAGADFIMTQLFFDIKAYDKFENSLREHPSGAFKDIILLPGLMPIQSYQMIKRT
TKLSHAKIPDNLMARLDAAKGDDEKIKQVGVDILSELVEQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDPQLDNEEAVIDDGPGVPVSIPAVQLNGLSPITPAARALSGRRH
SSMGSSDPHNRIIVSSASNPAYETTTAGLMASEPVNTRANTLAISEGVGAVGREATWDDF
PNGRWGDARSPAYGEIDGYGVSLHMSVTQAIRLWGTPKTIQDINNIFIRHIKGQLSAIPW
SEEELLPESNMIQQELLELNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVEL
FIPSSDWAGLVARLNEVTDNTICFYAANAAGDFVSSDSSGGLVLEGTEASTNAVTWGVFP
GKEIITPTIIEEVSFRAWAEEAFKIWGEWSKVYGKGSESEALLERIRTEYWLVNIIHHDY
VERDALWKLLSGEKEN
>A0A4Y8CG86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. CH185|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRG
>I3EB65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus methanolicus (strain MGA3 / ATCC 53907)|TrEMBL
MSIYLGNRLVSPDYFTVTSEMVPPRSWNPSPLVEQAVRARGYVDAVDLSDNLLAIARLSP
VVGAFFIRQVGMEPIVQVNLRDRNRMGIQSDLMGLAALGVKNITILGGYPARIGTEPNAK
EVYDLETMELVRYVRRFVDEGKLFDNTVMEEAPQMTIGVVENIAGKPVKELIDRLEAKID
AGANFVRTQLVFDLDLLGEWMEEARRRGLHERSYIMASILPLRDADHVDAVLKIPGIAIP
ETIIKRIKEADSPDEGMKMVVELIHKLRTIDGIRGIHIRPLGGMDRYVSTIVKEAGLMNR
KLEKIAEYAS
>R6Y5A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides merdae CAG:48|TrEMBL
MKVIDLINSSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQKTDIYHEHATDLQQQVNDFNKGIAIDGSVFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDDEAKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVYKVAKEVY
>R5GME6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:146|TrEMBL
MKNDGMDEMNIREYLENHKLLTDGAMGTYFDTVEKENYICSEEANITNPSLVRQIHKNYV
KNGAQLLRSNTFLANRETLLSLQQKRAEQFQNVSLKELVTKGYRLAEEVAREAYSESYPV
FPAADIGPILEGKESEETDILQQYYEICDSFLEAGANIFVLETFPDTEYVLKMAEYIRKI
CPEAFIIGQFSLTPTGYSRTGFHYKTILRDAVQSGLLDGAGLNCGIGAAHMKRFLEAYIE
EYGVPEDMILTALPNCGYPQIVRGHVIYSDSVTYFGEKIKEVSELGVRALGGCCGTTPEY
IGEIYRTLFQAEHTLKVPTRIVWTDAAGRIQKRQEQLVHIKSAEGKNKTIKKEQVVNTFR
RKLEKGELVCAVELDPPFDANDTKLVNGAKELLSTKADIITIADSPLARSRADASLMAAK
IKMQIGMDVMPHLACRDKNRIAIRSGLLGSYVNEIRNYLFVTGDPVAREDREFTKGVFDF
NSIRLMKFAQSMNQEIFADDTIFYGGALNQNGASPENIAGRMIKKMEAGCSYFLTQPVYD
EEGIKRLAFLKERTGAKILIGIMPLVSRRNALFIKNEMPGIYVPNRVVEKYKENASREEY
EEAAVEISKEIIEMGKEVGAGFYFMTPFNRVSLVKSILEYV
>A0A1M5WX58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium grantii DSM 8605|TrEMBL
MLKEYLKNNVLITDGAMGTYYSELTKDYSSLCEFANINNPEIIEKIHQDYIKAGAKLIRT
NTFSANSVSLEVSREKVSEVIEKGYKIAEVATKNTSVFIGASIGPIPKNQVEDSDLDILN
EYKFIVDTFLNLGAKIFVFETFSSLEYLKEISEYIKEKDSTVFILTQFAIRLNGLSRKGI
SINTFVEEVKSITYIDAYGFNCGSGPTHLYKHLKKLNIFSDIVSVLPNAGYPELVNERTI
YVNNPEYFSEIMFDVKKLGAKIIGGCCGTTPSHIKKLSESLNKNTADDSHFFHDDSIKTS
LITKKDNAFLNKLEKNEFVIAVELDPPYDTSIEKIMHGAQVCKDNNVDLVTVADSPRAIA
RVDSLMIAAKIKREIGIDTMPHICCRDKNINALRSGLLATHIEGIRNILAVTGDPVADVD
KHSTKSVFNLNSIKLMELISEMNKGTFEKDEITSCGALNLNVINKDAEVSRMIKKIDKGA
TFFLTQPLYDDASIEYLIKLKKEHDVKILAGIMPIVTYKNAQFLNNEVPGISIPDVYLDR
FHINMTKEEAEAVGVNLAVEIANKIKPHVDGLYFITPFNRFEMVMKIVNESNKSI
>A0A7C4VR01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatirhabdium butyrativorans|TrEMBL
MKSGSNLEKILLAGHFAFTGELGPPRGSDADEVRKKAGYLKGIVDAVNITDNQTAVVRMS
SWAASLIALQEGLEPNYQMVCRDRNRLAMQADILGAYALGIRNMLCLSGDHMKFGDHPNA
KGVFDIDSMQLIQTVKRMRDEGKFLSGADIEHPPKIFIGAASNPFADPFEWRVHRLAKKI
AAGVDFIQTQCIYNMEKFRKFIQMANDMGLTEKVYILAGVTPMKSVGMANYMKNKVPGMD
VPDEIIKRLKGVEKGKVAEEGIKIACEQIEEFKSMRGVAGVHLMAIEWEHKVPEIAERAG
MLPRPRVD
>A0A7M2BXQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenarthrobacter sp. YJN-5|TrEMBL
MLATRVEIIPTDGIVDVVNSALPAGSTVSITCLPHHGVESTVRTAIKLSELGFVAVPHIV
AKCVESQEHLSGILGDCAAAGITEVFAIGGDAPRAAGAYSTGVELVRDIAELSGGSMSVG
VAGYPEGHPSINGLQLMDALLEKQEFAGKIVTQMCFSAETIHNYVALLRKEGVTLPVHAG
VAGAVPKAKLISLASRIGVGASLKFLSRKGPLARKLILGERYAPDALIQELAARPGVEGI
QLYTFNSLEALPQ
>A0A7W3LSI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura namibiensis|TrEMBL
MRRVRPDRAPTVRELLADGRPTFSFEFFPPKTEKGARTLWRTIRELEPLHPAFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVDHSQAELRHLIGRFASVGVRNILALRGDPP
GDPMGEWVKHPEGVEYAAELVRMIRSYGDFCVGVAAFPYKHPRSGDIESDTRHFVAKCRA
GADYAITQMFFRAEDYLRLRDRVVAQGCDVPIIPGIMPVTQLSTIERSEQLSGAPFPPEV
RERFERVAGDPEAVRRLGIEHAAELCRELLDEGAPGIHFITFNKSTATREVYELLAGSGY
GANGSRPPMTA
>A0A8G0AAA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apibacter sp. ESL0404|TrEMBL
MKVTEHISNAKGKTLFSFEILPPKKGEDLQNIFSNIDPLMEFNPPFIDVTYHREEYEYRE
LPNGLIQKIVTRKRPGTVGICAAIQQKYKVDAVPHLICGGFNKEETENILIDFNFLGIDN
ILVLRGDPIKSEGIFKPHSHGHSYANELVSQVQNMNSGKYLHEEYAHGATDFCIGIAGYP
EKHFESPNLDTDLNYLKQKIDAGADYIVTQLFYDNTKYFEFVKKCKNIGITVPIIPGIKP
VSIKKHLNILPNIFHIDMPQELVMAVEKCKDNKAVYEVGIEWTVSQCKELMKQGVPVLHF
YSMGRSENIRKIAKQLF
>A0A8E6MVF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Newport str. CFSAN000827|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7C4VZA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatirhabdium butyrativorans|TrEMBL
MQLNQKLAEGKFVILAEMEPPKGADPSIMVRQSRRVKELVDGFLVPEMNKAVMRMSSLGG
AVVLQQNGMQALMQVCCRDRNRLALQADLLAASACGVQAVMAVRGEDVRFGDHPDAKAVY
DLDELTLLDAIQKMQQGKDLAGVDLATAPRFLVGASVNAAAKGEPLERELEAMAEKQKKG
VSFWVTPPIFDLDAFGPFLNRIDRSKTPILPTVLLLKSAGMARYMARNLENISIPDSLVF
RIQSAPDRVQECVRIAAETISAVKAKGFAGVLISTIGWEDRLPDILEQVR
>R0EGQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter vibrioides OR37|TrEMBL
MTLPPTRRVIGPVARAGERTDRPRVSFEFFPPKTPRMEENLWQAITRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILDETQLKPAAHLTCVGASREEVDEVIREYWQTGVRHIVSLRGD
PPPGEGGIGGVYVPRADGYANATELTRAVRAVAPFEVLVGVYPEKHPESPSIEHDIDVLK
QKIDAGATLGISQFFFDLDAFLRFVDKVRAAGITIPIVPGVMPVTNFNGLKTMAAACQTA
IPSWLANLFEGLDDDAETRRLIACSVAAEMCAKLREQGFEDFHFYTLNRADLVYAICRVL
GVREVSPAPAEAAA
>A0A3N4WU04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frederiksenia canicola|TrEMBL
MSYAKEIDLLNQSVADLNGKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERNRTHTIVKSIQQETGIVAAPHLTGIDATPDELRAIAKDYWDSGIRHIVALRGDEP
AGYAKKPFYASDLVALLKDVADFEISVAAYPEVHPEAKSAQSDLLYLKQKINAGASRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMSKMYQGL
DDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGVRPE
>G0SG99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)|TrEMBL
MEKITDKIAALPAGSDYFSLEFFPPKTAMGFANLRSRLDRMARALRPLFVNVTWGAGGST
ATKSLELAEICQRELGLTTCLHLTCTNMSRHLIDKALDDAKALGICNILALRGDPPRRSE
YQDLTDPDADGEEFNWAVDLIRYIRKRHGDYFCIGVAAYPEGHADESHPLGQSLEHDLPY
LVEKVRAGADFIMTQLFFDIDAYGRFEETLRSHPSGAFKNIPIIPGLMPIQSYQMIKRTT
KLSHAKIPESMSARLDAVKTDDEKVKAVGVDILSELVEQIREIKSRTAAEQPRGFHFYTL
NLEKAVTFIVERTGLLTPVTPSEENESAIDLNPLPEINLLRVDVNGANAAQADLRRRKAS
IGSDPHDRVIVPGRSPSHPDYEATALEASLPAEPINTRANTLAISEGEGVLGREATWDDF
PNGRWGDARSPAYGQIDGYGVSLHVTVPKALQLWGRPTTVQEVNDIMIRHLRGELETIPW
SEESFSPETDKIRERLIALNAKGWWTLASQPAVNGLRSTDETFGWGPPNGFVFQKAFVEF
FCPSKDWTALLEKLSIPEVRDVVCFYATNLRGDFISSDTLRQAERQQSKPEQSATSQIPR
DQQQPDEVASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFAIWGEWVKIYERGSETA
KFLESLRRDCWLVNVIHHDYVDAEALWELLLG
>W9IWN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum NRRL 32931|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDRIKAIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A7Z1RIV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hodgkinia cicadicola|TrEMBL
MINQTSVSFVSANSIYVKFSVEYFPPRNIFNLGKMIRSDLAPNQAKLLEFNSIICNSENK
NRLNPATFLLVILKRLCNCSIILHNLLIQMRRMLIPNASMFHDLGINNMLLISGDKYTTK
KRRSDNISPYKIRKLLRKKNVFNIGAGYPNSHILYSGSFQDLFTMMLNRESGCSMHITQI
FNHMDNFLRNNLRCSMFKLGSLLPGLFISSKHPLAVDINLKYGIYLTRPVKELLESEHLD
ERAAFLFNLYRIIEIIKNDITWIHVFTLNKTRNLKEIIWILNDLTYYIKYWRLTNCNECY
AIMSDMHNAYKRR
>A0A7X1FVT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium piscinae|TrEMBL
MANPLIHPNWDRPPVRITEGYSLEMTAKDEPSLRDAAPLIAPDTPIAITYLPGEAMAARV
AATVAVRDLGFEPMPHFSARRILSQDDFGGYLKAVVEQAGVRRCFIVAGDPPAPEGPYAD
TMALLATGAFEQAGIQAIGIGGHPEGHPNMTPAECWDVLGRKVAEIERRGMAPLIVTQFG
FDPDAFLGWLEQLRARGIACPVRIGVPGPAGIKRLLAYAARCGVGASTAVLKKYGISVAN
LLGTAGPDRLVDAFERGLGPQHGRVRLHFYPFGGMAKTVQWIAERDARTAG
>A0A0Q4ERH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. Leaf201|TrEMBL
MKITDHIKKANGKTLFSLEVVPPQKGIGIEDLYRNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYSVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTQGGNASAMDLVHQINDLGRGKYLHNEEQECDEHNKFCVGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKARAMGISVPIIPGI
KPIATKKHLKILPQIFKIDLPEELINEVEKAKNNEAVKQIGVEWAISQCRELLDFGVPVL
HFYSMGKSDNIKKVAGALF
>A0A7Z0WNJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola xinjiangensis|TrEMBL
MRNKELLERPRYEVIPTASVEDRILDSVPREITVTITASPTKGLEPTFALAERLAAQGFR
TVPHVSARLVRDEIHLKEIVDRLVGAGIEDVFVPAGDSTTPAGRYDGALALLADLAALGR
PFRDVGITGYPESHPTITDDVVVQSMWDKRVHATYIVSNLCFAPKSLATWVQRVRRRGVT
LPILLGLAGPVQRAKLVSMATKIGVGESTRFLLRHGSWFVRMATPGAYSPERLLTRTALP
DGDVAGLHVFTFNQVAETERWRRDLLTTR
>A7HND8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium nodosum (strain ATCC 35602 / DSM 5306 / Rt17-B1)|TrEMBL
MDLQEISDFYKKRFILETLPPRGVVLEKYVDFCIKAVESGAEIIAVTDLPMGSARVSPIA
PAHILVEKGIDVIMHFSRTTRNAIRIEGDLIASHMLGIKNLLILSGDDPRVGTYPFSSCI
EDFSIYDVFKLVKLLNEKGEDLAGLKIFGKFSFNSGGVFSPFEKDYKQTIQRMNTKIETG
CLFFVSQPVFNESTILNFLKKAEGDLNETKIYVSLMVFESVQQLEYFSKVPGVFVPKEYF
HQKDDRALKNYSYKNCLGIIEKLSPYVQGFYLTSTTKDLEIIKGLAEVIQGAD
>A0A1V1PBP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Magnetoglobus multicellularis str. Araruama|TrEMBL
MSTKTPSKLEKILVSGQLAVTSECGPPRGSDPEDITRKAELIKNHVDAINITDNQTSVTR
MCSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAASYDIHNMLCLSGDHQSFGDCK
LGQNVHDLDSIQLIQTVRMMRDEAKFIGGDDIKRPPKMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNLDLFEKWMEGVRERGLHEKVYILAGLTPMKSAGMARYMKNRVPG
MDVPDEVVKRLAGVPKDKQAQEGIDICIESIERLKSVEGVRGFHVMAIEWEEKVPEIVER
AGLHPRPTISE
>A0A1V1PFA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Magnetoglobus multicellularis str. Araruama|TrEMBL
MNKIKEKLKTKQFVTIAELTPPKGTNTNQLINNATAVKDHVDAFLIPDIPNAIMRMSAFS
TACLLQKDGISSIVQMNCRDRNQLALQADLLGAYANGFHCVMIVEGDDPKTGDHHSAKGV
FDVSLSELFAGTKAMSEGFDMAGMELDGAAHFLVGAPLKINSKISDRFYLRNMITEYMET
GVSFFVTQPIFNLQMLGEFYESVKDLQPIIIPTVLLFKSLGMARYMSRNVPSIDIPQEII
KQIQKSKDKNNECLAICRQTIASIKESGLQGVSVSTIGWEHKLVDILS
>A0A2N6D398|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denitrovibrio sp|TrEMBL
MKISDILKAKRTVSFEFFPPKKEETEQVLFKTIKDLRKYNPDFVSVTYGAGGSTRDKTLE
WTKCMKQEHDYSVMMHLTCVAASEQKIEAVTDSLTGLQVDNILALRGDMPDDMPKEDISD
EFQYASDLVRYIRKTTGDKFSIGVAGYPEKHTEAKSMEADIESLKRKVDEGADFIITQLF
FDNYHFYNYLEKVRAVGIDVPIIAGIMPILNLSQAVRFTQMCGATIPKPLVAKLDGATVE
DQYKIGMEFAAKQCGGLWASGVEGLHFYTLNKYNATEELIKSVF
>A0A433RZ84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodobacter sp. E13|TrEMBL
MTKTPNISFEFFPPQTLDASFRLWETVQTLAPLNPNFVSVTYGAGGTTRKLTHEAVGAIG
SNYGLNVAAHLTCVDATRAETLEIAESYAAAGVTEIVALRGDAPKGAARFTPHPEGFASS
VELVEALAATGKFKLRVGAYPEPHPDSADTLADVRFLKRKIEAGASSAMTQFFFEAETFL
RFRDACVKEGITAPIIPGILPIQSWEGTKKFAARCGTQVPAWLDEAFAAAKRDGREELLA
TAICTELCDTLIGEGVEDLHFYTLNKPHLTREVCHALGVTPQVELQNVA
>A0A0Q8VG76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root224|TrEMBL
MANTQAPRIGDLVRAGERSFSFEFFPPKDEAGEEQLWQAIRELEPYRPTFVSVTYGAGGS
TRDTTVRITGRIAAETSMTAMGHLTCVGHTREELEGVLDSYAEVGIGNVLVLRGDPQEGP
QAPWTPTDGGFTYAQELVELARGRGDFSVGVAAFPERHPASETLDQDADVLVAKARAGAE
FAITQMFFRAEDYFALVERVRARGVDLPILPGIMPILNLGNIRRQGEMIGTEVPASVVER
ISAHEGDPAAMRAAGIALAAELCEELLDGGAPGLHFYTLNRSKATREIFSALNMSV
>A0A1D9G2T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena producens JHB|TrEMBL
MTNPTNNSFRTAVESGEFLITAEVAPPKGGNAAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILHQQGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQRRFER
KLEAGAQFFQSQLICDFDRLEKFMDQIAAGTNKPILAGIFLLKSAKNAKFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSAVNDLVCK
>A0A089IL63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL H7-0737|TrEMBL
MGAAESTFKQKILSKKPGILTYGMTPPKASHSPEKISEIAQKQVERLKNVDLDALILYDV
QEEAERVDHERPYPYLPTIDPAVYGDKYLRQVEVPKIIYRCVGNDTRASFADWIKTDESE
DRFSVYVGASSSKQEVKLNLPDAYKLSKQLNSNLNFGGVVIPERHIKKNDEHTRIVEKIN
NGCSFFITQATYNVEASKNLLSDLYYYNTNKGFEMVPILFNLAPCGTAKTLQFMKWLGIS
IPGWLENELKYSNDILDKSIQLSQKIFEELFEFGMEKGIPIGCSIESVSTTKLEIEASIQ
LAKDVKAFLDKKLLSLESR
>A0A2T0BQU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium luticellarii|TrEMBL
MSFSFEVFPPKADKPLDNLLDTLEHLYVFNPDFISCTYGAGGTNAGRNVEVCSAIAKSGR
TIPVTHFTCIGNSREDIRKSLHTYLDKGVNHILALRGDFPEGWQGTRGDFNYANELVEFI
KKNFPEFCIAAAGDPEKHFQADSFEEDIAHLRVKQDAGADYIMTQLCHDVEQYKWWVDKI
RKAGVSLPIDVGLMPVLSKDPIIRMTVSNGSSIPRELAEIIARYGDNPEDFKKAGKEYTI
KQIYSFINAGINGLHIYSLNRWKDVTDILNESGIRNLNTSAAR
>F8A836|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfatator indicus (strain DSM 15286 / JCM 11887 / CIR29812)|TrEMBL
MVCSFRKCLENPDLFTITYELVPGRSTRLRQFQKIIKFAEEATKDGRLHGLTITENAGGH
PALSPAVLGREILKLGLEPVLHFTCKDKNRNQIESTLFARDREGLHNLLVMTGDFPLYGF
MGRAKPVFDLDAVHLLQLITEMEKGIELPPEAPGGGVKLPPMPFFKGCVVTPFKKFEAEL
MPQYYKLHRKIKAGAHFVITQVGFDARKFHELLLYMREEKLNVPLIGSVFITDVRMARIF
HKGIIPGIEITAEYLAQIEEEARQEKDTYRAALIRAAKLVAILRGMGYDGVHISGGKVRY
EDIAFLLDKAEEFYPRWKDFLPEFRNAPEGTFYLYSKDPETGLNLPERYEKLSPAQKKPL
MFTLNLWVHDLFFEPGKGFYNFAVKYAQKIDGSSFEPWFTKFEYAVKGLLFDCQRCGDCT
LGEMAYLCPQSGCAKNLLNGPCGGSKDGYCEVDSSKKCHYVKVYERLKAIGKRHLLKEGF
IPPRDWGLSGRSSWLNFYLGRDHHRHPVPKNFQEPK
>A0A7Y3KKP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidia bacterium|TrEMBL
MKVIDRLKKAKSTLFSFEILPPLKGKSIQSIYDSIDPLLDFSPSFINVTYHREEYIFKKR
EGGFLERIPVRKRPGTVGICAAIINKYKIDTVPHLICGGFTKEETENALIDLQFLGIDNV
LALRGDAVKSESAFVPEPGGNEHALDLVKQIVLMNHGKYLNEEVEDLSKHSSYCIGVAGY
PEKHFECPNMKADLKHLKAKVDAGAEYVVTQLFYNNDKYFEYLESVKQLGIHVPVIPGIK
PITSKKQLLSLPKFFHVDIPEGLAEAVEKCENDNEAKEVGIEWTIAQCKELIKHGAPCIH
FYTMGRSESVRKIAKAVF
>A0A524NUD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidia bacterium|TrEMBL
ARLDLSQASVIGLNCTVGPKPMLDFVEQIRGISSKPLCIMPNAGRPQYTDGRMIYMSTPE
YFSVYTRRFIDKGVRMMGGCCGTTPDHIAKMANSLAMKQTRIQHSINIGVKPVTEEPLPD
PVPAAEKSRLAEKLHAGKQVVLVEMVPPRSIDITLPLEGAKLLKEHGVDAINIPDGPRAS
ARMTGLALSVLLRNQVDIETVLHYTCRDRNLLGMQSDLLGAAAMGVRNILAITGDPPMIG
DYPQATAVFDIDSIGLVHLIDNLNHGIDMGEKRIGDPTSFFTGVGMDPNSVNPENEIHRL
QLKKEAGAEYVITQPVFDVESLEAFLEKADMGDMFLVAGIWPLVSLRNAEFMKNEVPGVF
VPDSIIKRMAAFETKEDQLKAGIEIAQAMVDRVLGFVQGIQVSAPFGRYKLAVEVAEAVL
NAE
>A0A7Y2TI27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidia bacterium|TrEMBL
MKLTETISPNKTLFSFEVLPPLKGKSINSLFKAIDPLMEFNPAFVDVTYHREEYILKQRA
DGSYDKISTKKRPGTVAICAAIKNKYQVEAVPHIICGGFSKDETENALIDLNFLGIQNVL
ALRGDNLREERNFTPEKDGNANSLDLIRQINDMNNGIYLDQELENPTETDFCIGAAGYPE
KHIDAPNMESDLKFLKRKVDAGAEFITTQMFFDNQKYFEYVKRCREAGINVPIIPGIKPI
TRKAHFYTLPKIFNIDIPVDLYNELDKAKDDAAARKIGIEWCIQQTKELKAANVPAIHFY
TMSYASSTKEVVSQIF
>A0A7S7IZM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MSEEKSRLQRLFESGTFVVTGEVGPPMGADSGHVYHAAEALTGIIDAANVTDNQTSILRM
SSIAASLLVQQKGLEAVVQMTCRDRNRIAIQSDLLGAWALGLRNLLVLSGDHQSFGNDRH
AKNVYDVDSVQLIKMLSDLQRDGVFYNGKKAKGVPEFFIGTTANPFADPEELQLIRLKKK
IQAGAKFVQTQSIYDIDKFEAWMEKVRAWGLHKEAYIEAGVLVNKSLRSIEMTQKVPGMD
IPDALVERMRNSEDPKEEGIRIVLELIERIKKIEGIRGLHIMAVGWEEIVPVVVERAGLS
PRPIVE
>A0A0Q9KF23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Soil522|TrEMBL
MKPDLREALQQRILTGDGAMGTYLYQMGFPVGVSYEEFNTLRPDVIENIHRRYYEAGARV
IETNTFSANFEKLSKYGLEGEMDAINRAGVRAARAAIGDDAYVVGAVGSIRDGKLKNLRT
AKVIEAYQRQMHALLDEGVDGILLETFYDLDEMLLALRIARAASDVPVICQFAVEDVGRT
QDGNGMKGAFDQLQEAGADVVGFNCRSGPTGIMRAIDSIAGPVGLPLSVYPNAGIPDYID
GKYTYSAGPEYFAETAQRFADRGARLIGGCCGTTPEHIKAIAAALDGYIPQIGQPAAAVA
AVEKIVIKPNEKPAAEDKAPQKLAVQEPSIVDLVQKRHTVIVELDPPRDLDIRKFMDGAA
ALKEAKADAVTMADNSLAVTRMSNIALAALVQEKVGIRPLVHIACRDRNLIGTQSHMMGL
DALDIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNDGTAFSGKPLKQKAKFV
VGAAFNPNVKYLDKAVQRLERKISSGADYIMTQPIYDPDLIERVAEATKHLSVPVFIGIM
PLASGRNAEYLHNEVPGIQLSDEVRQRMSGLEGEAGRAEGVQIAKELLDAALPYFKGIYL
ITPFMFYEMGVQLTEYVWRKTERM
>A0A829PP90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus MAB_030201_1075|TrEMBL
MTTNPLDRDGPVAELQDPGSIADRLTAVQPGEIAFSVEFMPPRDEAAEARLWRAARVFER
YRPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWVPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLLNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPTALEERLLRAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTARG
>A0A239QL13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MRILDTVRSTDLSLSFEVFPPKTDATFEEVLKATEEIAALKPSFISVTYGAGGKGGKYTL
EIARTLQNTDGVETLAHLTCVGAGKEDISSYLQTLKAAGIRNIMALRGDLPEGMTPEDMK
NSPYPHASDLIREIRKAGDFCIGAACYPEVHPESSVQAEDLRYLKEKVDAGADFLTTQMF
FDNNLLYNFLYKLRETGVTVPVVPGIMPITKANQVKRALKLSGSFMPRRFTSLVDKFGSS
PEAMQRAGIIYACDQIIDLYANGIRHVHVYTMNKPDVAAAIQNHLSGMLGRTF
>A0A0Q4USZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Curtobacterium sp. Leaf261|TrEMBL
MPDARPRVSFELFPPRTAAAEARLRTTIQELASVRPAFISVTYGAGGSSRGASLDIVRRV
IRDAGVPPLAHLTCVGLTAEQTAHLVRRFLDAGVRHFLALRGDPPRNADGSDAPCDPSVG
LGSAAELVQLIHRVQAERAQFDDALLPSSARAAGAGPGGARLPAQGRKVEIAVAAFPNGH
PRSRDLAQDIDALLAKQAAGATLAITQLFYRADDYLTFVDRCQAAGLTIPILPGLMPVSS
PKRLLGATSLAQETVPADLLARLESADSDEERFERGADHAAALADQVLAGGAPGLHLYTF
NQHALPLAVLDRLRTTTTTPPTQTPSR
>A0A353W2K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MFIKDKFIKKNKVISLEIFPPNNNMTLKQILDVIDELSIFRPDYISVTYGASGNANNNYT
VDIAEYIKEKYTIEAMPHLTCIGSNKEKINEILKLMIKKNLKNVLALRGDLPKDILSDST
NGTDYSYASDLIGHIRGSELPISVAAACYPEGHIEASSLNADIKNLKIKVDRGVDFLITQ
LFFDNNRFYDFKDKIVKNNINTPITIGIMPVTNVKQIRRIIALSGASIPLKLKTLLDQYE
NDNKGMFQAGIDYACQQMDELNHLDVNGFHLYVMNKPEIARMIYKNMNW
>A0A3M8AL44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces tardus|TrEMBL
MEYGPCGGVEFDGRCEVGAFRCVFLGDGIRTWTGIDRSESRPAPAPPTQGAVAMTALLAR
RQVVVADFPARALDAGSVVRCARILSGAVDATLAGDAGSARVQYSPSLRASLIRREGLAV
WSGVNCRDRNRVALEGELAGLAEVGVAGVHCVTGDHTRTGHRPDAAPVFDLDSTELASLA
RAAGHLVSVAESPAAPPVADRAARLLEKEHAGAQVCFVNHCGGDESVATFIREARALGSA
LRFIPCVPVVVDRGSAELLESFTTLRLPDGFLAGIRSAADPRRAGIEAAVDSGERMLRLD
GVAGVDLSGGPGVGGEEAFAVALAEISERLGLVD
>A0A015VQ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis str. 3998T(B)3|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKA
>A0A352ILW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKIIEKFKENRPLISFEIFPPKPDYPIDTIFNTIDELYSLEPDFMSVTYGAGGSTKDRTV
EISSYIQNKYNLTSNAHVTCISSSKEEVQNISKSLKEKNIQNVMALRGDYPKNSLSGLPV
DRYNNSVELIEYFKQNTDFCIGAACYPEKHPDAKDLNADIDFLKRKMDAGADYLVTQLFF
DNGMFYDFYDKAIKKGIYLPISVGIMPILNKRQITSIVRLTGNSIPNKFRRLLDKYENNP
EALKEAGMSYAVSQIIDLLSWGVDGIHIYTMNKPSTARKILENISAIRSVLTNERKIS
>A0A4U8UJH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter apodemus|TrEMBL
MTNTCLIEDFINKLKNSQKCFTYEFSTPSSFSLESFYDFSDSLLQQLDAFVCTDSPLAKL
KHSATLASLKLQNTFKIPSITTMSMRDRNTLSLQSELIGMNSLDLRLVLALTGDPLRLGN
QTQAKGVFEGNSNLLLKIIKQLNQAKDINNQNISGKCKRIYPFSVLNAYPNKKETSYKKM
KEKIQNGAEAIFTQPIYDLQIAKELISWNKEINQECKTQSVLVLGFFPITSYKTALFLHN
KLPGVYVPQDWLDALEKAHNNEAAIGLAKSKNFFEKLRCFYQKIHFMSANKPKLIENILC
>A0A1F6SX17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Muproteobacteria bacterium RBG_16_64_10|TrEMBL
MNSQKTFPRVFSCEYFPPKDDAARDKLYATTRELAVLKPKYFSVTYGAGGSTQAGTYEMV
KWIKEQGLDAAPHISCVGATRATIVEQLQRYKTLGIKRIVALGGDLPSGMASPGEFRFAY
QLVELIRKETGDWFHIEVAAYPEMHPRAANINDDLKYFRQKVAAGASAALTQYFYNPDAY
VRFVYECEKLGLKLPVVPGIMPITNYKQLARFSDACGAEIPRWIRKRLEGFGDDLESLRA
FGLDVTTQLCEKLLAAGAPGLHFYTMNRATPTREIWNRLGLK
>A0A061ESA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Theobroma cacao|TrEMBL
MKVIEKIRTLQEEQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGSDGVATPEAYQNDLEYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPADITNALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRFLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSQN
PSYGALTDYQFMRPRARGKKLHEEWATPLKSIDDIQGNSRVIVWAS
>A0A0M9VRA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malassezia pachydermatis|TrEMBL
MSPTTAHGAARIDEKILATPSDAYLWSLEFFPPKTTLGLANLCSRIERMVTSLGPGWVHV
TWGTGGTTRDTSLELAARVQLGVYDPNEDYKAVTEPREHACNVCLHLTCTNVDRAYLDSA
LDGAKRFGIRNILALRGDPPRGEEYWVATDQRFQYASDLVRYIKEQHGDYFCIGVAGYPE
GHAQGADRDVPQDMKFLKAKQDAGAQFIVTQLFYDASSFARWYHACRAAGITVPIIPGIM
PIQNYTSFRRMANLCGVRVPADTLKKLEPIKMDDAKVKEMGIELSIQLIREVQKETGIHA
FHMYTLNLEKSVTQVARAFVGEGHVHQGLGADTWDEFPNGRYTDARSPAFGEVDGYGASL
KVTPDQAIQLWGTPVDKDDISKLFVSYVAGELSCMPWCDSPVWEETARLLPVLRHLNAPH
SKGGKGWWTVGSQPAVDGCDSSDPTYGFGPQGGYIFQKAFVELFLSEADKQALVAAIAAS
DEPVTYFAGTCDPASFETNVEGTGLNTVTWGVFPGREVAQSTIIEEASFRAWREEAFAIW
HEWEMLFPPRSATRQLLHRIHDERWLITVVHHNYKDPDALWKLLDHVVLP
>A0A447JQM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Daytona|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1F8MZZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_54_8|TrEMBL
MSLKERLAGGKFVITAEVGPPKGVHIEEMKRNAELLKGRVDATNTTDQQSSVMRMGSLAG
CVLLRQWGLEPIMQATCRDRNRLALQSDFLSAYALGIENALCLTGDHVALGDHPDAKPVF
DLDSVSLLQAIRRLEQGFDLGGKELKGSPRFFLGACVTPAANPMEPQIFKMEKKVKAGAQ
FFQTQAMYDPKQFEQFMKAVKHLKVPILVGIVLLRSAAQARFMNKNVAGISVPQSLIDEM
DKAEKKAEKGIEIAARLINEMKGMCQGVHIMAIGMEDRVPRVLDAAGL
>A0A6L8DE43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDLPLKTLRDALRGKDFAVVGQLRLHQDHGRDDLIRQAECLSPAVDAVAVTDNPYGLVHM
SGLVVASILLQRGIDPVLQISARDRNRIALKSELLGAAALGVTSLVLQRGNKLPKDGQPQ
VKEVFDTGAKKFLAAAKQLSSFQVAQGLPELFLGTMVTVFDPDDGWQPTEIKAKVEAGAQ
FVQTQACLNVALLRRYMKFLVAAQVARRCHVLVSVPVLTSVESARWLAAHHRGAVIPDRL
VGQFKRAKDPESFGIALCAETIQAIREIPGVGGVNLSTTGNPEAIVAAVNQAALD
>E1K1G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solidesulfovibrio fructosivorans JJ]|TrEMBL
MRIKELIQAKRPFVSLEFFPPKQREAWAGFFEVVERLIPVHPLFVSVTYGAGGSTHAHTL
EIVSRLKTAYGLEPMAHLTCVGASREKIRGFLDALAAAGVDNVLALRGDPPKGQEDFVPD
SDDFQHASDLVSFISQERPGLGIGVAGYPECHPAAISPEADLEFLRQKICLGGDFVVTQL
FFDNDAYFGFVDKCRAVGIDAPIVPGVLPVMSLASVKRLVGMCGAHLPPAYLAELERADA
AGGNAAVAEAGIAYARKQAQDLIARGAPGVHLYTLNKAEAVLSIVAGLDL
>A0A5C6V1J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradymonadales bacterium TMQ1|TrEMBL
MSQIQMQSPFLKALAAGPIVFDGAIGTQLYERGIYINKSFDDANLSRPDLVAAVHAEYVS
AGAEVITTNTFSSNRIKLKRHGLEERAAEIALAGARIAREVAGDLALVAGSVGPTGRTPT
MLTERELDEMRQAFREQIAALAEGGVDVIVLETFRQLAEIRMALEAAREVCDLPVIAQMS
FDGERRTGDGADPERVAMLLADWGADVVGANCMEGPHVLYDVVVDMLSCGLPVIAQPNAG
YPRKVDERLVYMATPEYFGVYARRFFKAGVRLVGGCCGTGPDHIRQVAAAARMLGGGRAS
VEVSTARMPRKEVEPECVQSQKAPTRLAEKIEAAHRSRAAGEPVSRENFVVSVEVNPPSG
LRADRAIEAARMLVEGGVDVINIADGPRASVRMANWALGRMLQESLDIEVILHLCGRDRN
LLGLQSDVLAFEALDLRNLVVITGDPPKVGDYPHATAVFDLDSVGILRMIDNFNHGVDPA
GKPVGDATAFYCACGAEPAAADYERELRRLELKKAAGARFVMTQPVYDPAVLDRFLADIE
HLDLPVLVGLLPLASARNAEFLHNEVPGMAVPLEVRERMRAAGTGQAARAEGVRIAQETL
EAVGSRVAGAYIMPPFGRYEAALEILSCLPGYATT
>A0A7L8RL86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus sp. GY-402|TrEMBL
MSYAKEIDHLNHSLAELNGNINVSFEFFPAKNENMETMLWDSIHRLAPLKPKFVSVTYGA
NSGERDRTHSIVKRIRNETGLIAAPHLTGIDATPDELREIARDYWDNGIRNIVALRGDIP
AGYTKPPFYALDLVKLLKEVADFDISVAAYPEVHPEAKSAQADLIYLKQKVEAGANRAIT
QFFFDVDSYLRFRDRCVAVGIEVEIVPGILPVTNFKQLQKMATLTNVKIPGWMNKMYEGL
DNDQTTRNLVAASIAMDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGVRPAS
>A0A1V6DDK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium ADurb.Bin120|TrEMBL
MCENVNKFKNRLISSDRPIVTDGAMGTLLHDRGVKIDACFDALNLTQPAAVAEIHLEYIQ
AGAEIIKTNTFGANRIKLERHGLIDRVEEINVAAVNLAQRVIMASFRDVMIAGDVGPLGM
PLAPFGRIQPEEAFEIYVEQISALVKAGVDLILIETMVDLYAVKAAVNAARYVDPDIPVI
ASMTFTLDRRTLLGNTPQEVAQRMDEYGVDVIGVNCSGGPAQLLHILRLMKSAVPSGRFS
VMPNAGLPEKVGGRIMYSAGPDYFHDYALSFWRAGADVVGGCCGTTPAHIAMMTKAVANT
SKEDLVNGVSVLESTVEVVQEPAEDRSHLAQKLDAGKFVIAVEMDPPRGLSTQKLLAGAS
LLADAGADVINVADSPMARMRMSAWAVCQLIQSKFDIETTLHFPTRGRNLLRVQGDLLAA
HALNIRNVFVIMGDPTAIGDYPDANDAYDLVPTGLIRLIKEKFNIGKDHSGGLIGQPTSF
FIGAAMNLTPNNPAQEIRVLKKKIDAGVDFFMTQPVFDVQKAGAFFHRCQQEIEWKNIPV
LAGVLPLVTDRHARFLHHEVPGIQIPASIQQRMSAAGEASVQEGVRIAVELIDELRSVYQ
GVYIMPAFNRFDMVAEIIDKIRGEKVT
>A0A7C3CXM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKSQSKFTPTFSLEFFPPKTATGAENLRRTRDEFAKLKPAYISVTFGAGGSTQDGTIETV
TEIQQAGIPTAPHLSCIASSTEQLREILQLYKTRGINRIVALRGDLPSGMQSPGELRYAN
ELVAFIRKETGDFFKIEVAAYPEIHPQASSASEDLKNFKRKVDAGADAAITQYFFNPDAY
FNFIDNCEALAIDIPVIPGIMPITNYKQLARFSDACGSEIPRWIRKRLEDYGDDVASIKA
FGLDYTIKLCERLLSQGAPGIHFYSMNKVEPTKEIWMTLGLENP
>A0A7C1A0T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MESQKRHNPVYSFEFFPPKTPEGVEKLRRVRARLAVLGPRFFSVTFGAGGSTRERTFETV
AEIQRESGIEAAPHLSCIEATREGVRAILSRYRDEGIRHIVALRGDLPSGSGTGGPREFR
YAADLVAFIRAETGRHFFIEVAAYPEVHPQARGARADLLNFQRKVEAGADGAITQYFYNA
DAYLRFVDECEARGLDLPIVPGIMPITNHNRLAHFSDACGAEIPRWIRKRLEDFGDDRDS
IRAFGTEVVSDLCRRLLEAGAPGLHFYTLNQAAPSLAIWENLGLGRIDTAGSPSAHRP
>A0A098E889|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|groundwater metagenome|TrEMBL
MSLLREKFNRKFIATGEVSPPPCPDKTLFAHEVEEMKPLMGRILGVNVVDGPGGRVLMSS
LGASIYMIQHGVEPILQQVVRDKNSVALQNDLLSAAIFGIENVLSITGDHPACRASDNPK
SKPVYDMDSTTLIVMLKKLNEGKLWNGKDTNYENKNLNAKTNFFIGASLSPTSSPLDGEI
YKVKRKLIAGCDFFQTQGVFSIDPITNFLNLYEKTIGEKIADKVLVGIVPIWSYGMFKYL
LTLPGIVVGEKFLNEINEARKKQKETGQKGIIEEAGVNLCVDLVDKIKGQGIKGVHIMPV
GNLHAMKEIMDKSGL
>A0A6L8ASV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MRFDDEPIEPGDPLPILPGHHSAGRFERLLRAGVFTITAELSPPDSANAEDVYARARIFD
GYVDGINATDGSGANCHMSSSGVCALLTRAGYAPVMQISCRDRNRIAIQGDVLGAAAMGV
NNLLCLTGDGVAVGDHPGAKPVFDLDAIALLNIVRTMREQACFESGRALTTPPKVFLGSA
ANPFVPPLDFQVARLAKKALAGAEFVQTQYCFDVPLLERFMQQVRDEGLDKRLFILVGIG
PLASARAAEWMRTHVPGVRIPDAVIDRLRRARGKGAAKAEGKRICIDILERVREIPGVCG
VHLMAYRQEEAVAEIIDRSRALDGRIPWYPGRDRHSRPAREVDSPTELPEEMLA
>A0A525CGR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSYRPPTNEKVFSFEFFPPRTPEGIEKLKGVRDRLALYNPLFFSVTFGAGGTTRDDTFET
VIDIQKESGIDAAPHLSCIGSTQENISAILKQYMDNDISRIVALRGDLPSGMRDVGEFQY
ANELVEFIRKETGDHFLIEVACYPEFHPQATSPQDDLINFKRKVDAGADSAITQYFFNPD
SYFSFVESTHKLGVEIPIIPGIMPITNYTQLARFSDACGAEIPRWIRKRLEGYGDDMESL
KAFGIEVVTSMCDTLLNQGVPGLHFYTMNQANTVISIWENLGLAPLD
>A0A344U568|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces globosus|TrEMBL
MALGTASTRTDRARTVRDLLASGDPSYSFEFWAPKTEKGERNLWDALRRIEAVAPSFVSV
TYGAGGSTRGGTVKATQQIASDTTLTPVAHLTAVDHSIAELRNVIGQFADAGIRNMLAVR
GDPPGDPMGPWVAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSAEKAGCETPIIPEVMPVVAVRQLDRLPQLSNAVF
PGAVKERMLAVKDDPAAVRSMGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHKRA
>A0A521RLC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSYAQIHPNWDRDPEFITEGFSVEITAKEIHGLREAAPKLPPDTPVAITFLRGDTLEARL
AAAREVRALGFEPMPHFSARRIQSETEFKKTVESMVKEARVRRCFVIAGDPPTPEGPYQD
SASLIETGLFEANGILAIGIAGHPQGHPNMTDEECFSVLEKKCAMIHARGMKPIIVTQFG
FDPDAFMQWLVDLRKRGIDAPVRIGVPGPTNIQSLLKFATRCGVTASASVLAKYGISITK
LLGTAGPDKMVDVFARSFGSEHGRVRLHFYSFGGLPKTVEWIENYTKHL
>A0A352JXN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSKQIIKAMHQWSIEVTPSSSKKIDDFREVLPVGTTVNVTAIPGSAPEQTLSTVHRLVSQ
EMNAVPHIAARGIESVAALEALITRFREAHVTEVLLIAGGYKQPVGEFSSSIDVLETGLL
EKLGIKKVGVAGHPEGSPDISKAGLADALKRKNVIAQESGLDMYLETQFCFDAQAILDWE
AQIREAGNRLPIRIGLAGPARLKTLIHFAVISGVGPSLQFLKKQARNVTKLLTVQDPFEL
IETLAPHIDPQSASALQAIHLYPFGDFAQTARFANQLALEGTR
>B6K4Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schizosaccharomyces japonicus (strain yFS275 / FY16936)|TrEMBL
MKITDKLQLPEYRDRVTWSYEYFPPKTSTGVVNLYNRIERMRDWGHPTFVDVTWGAGGSS
SDLTPVIVKVTQSDYGLDTCMHLTCTNMATKQIDEALERAYKVGCRNILALRGDPVKHES
EWTALEGGFEYACDLVRHIRKKYGDEFCIGVAGYPEGYAPGDDIDATIKHLKIKVDEGAS
FIVTQMFYDAENFVDWVKRVRAAGITIPIFPGIMPIQSWSTFNRRCEWSGVRIPQHFIDA
LEPLKDDDALVREKGSELMAEMCQKLVDNGITRLHFYTMNLEKATKMIIEKMGLLNQYIE
TPKNELTSHIRSPSQLQFLDNPRPNETVRPMFWKTRSQSFISRTEQWDEFPNGRWGDSRS
PAFGEFDPKHHGLKQTDAEIRALWGSPENIRDLGNVFAAYCERKLACLPWSDIPLSGESA
IIADKLAELNRQGILTINSQPPVCAAPSTDPLFGWGPAHGYVFQKAYLEFFMHPDQVKSL
LEVIPSFKTVQYYITDYEGSLETNGELDVPSAVTWGVFPNSEVIQPTVVESASFLAWKDE
AYSLGLSWAKAHSSTSAPFKLLTNIVKEWKLCVIVDNDFRAKDTLFRFLEQVKPLRELHP
EFFSH
>A0A2E5NHX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKRPTILLAILWIRINPDGRTLTKSNHKMKTFNAKVSLKGWSIEITPKESKTISCFSAFL
EKGTKVNVTSLPKTSVRDTLTAVEKLKRDGMNPIPHITARTTADEGDLARVVEKYADLEI
SEVLIIAGTKDQPAGRFSSSADLISSGVFEHFGIVNIGVAGHPEGSPDITEQQLQDALDQ
KNHLAVSRNLNIFLETQFCFDAQRIINWEKVIRDRGNMLPIRVGIAGPTKFLSLINFAIK
AGVGPSLKFLINERDKLTKLVNSYDPTELICSLAPQFSPEANTCFESVHFYAFGGFRKTA
VFAQELFK
>A0A3D0ZYC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSLFKEKLTEGDFVVTSELTPPKGIDIGKMLTTAEQLKECVDAFNITDSHNARMSLSPLA
AAHALIRAEVEPILQMTTRDRNRIALQSDMLGAASLGVQHLVCMGGDPPHLGDHPDAKPV
FDFSTEALISAAAGLAMGKDSTGNELNKAPELNVGAVVNPGADDLDTEITRLEKKIESGA
RYFQTQAIFDPAAFEAFMNRVMSFQVPIIAGILPVKSAKMADHMNRNVPGIDVPETIVQT
IEAAEDVKSVSADISAEIIREIRPMCQGVHIMAIGWEALIPTILEKAK
>A0A357IED0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTLGEPTVPHTGTGKSQQPTFSFEFFPPRTALMQRKFWRTVGRMEALSPAFFSVTYGALG
SGQTQSVDTVKALCAESDVPVAAHLTCVGANRETLNAVIHDLRDCGIRGVVALRGDGEEP
GAPFCAHPDGYQSVPELVTYLRGSGEQAISVAAYPEVHPQASSPEEDLLHLKRKLDAGAD
QAITQYFFEAEDFLRFRDRAIAAGIAKPIIPGILPIHNYQRVVQFSQRCGASVPTRFADD
YARLDNDPQGRYEFSVALAVRLGETLMAEGVSQFHFYTLNQTDLSHAVCCELLREPQ
>A0A1F8NYP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_48_8|TrEMBL
MSEASSNGYKSGSRLERVLRAGHFAVTGELGPPQGAEANVIREKAKLLKGLVDAVNITDN
QTAIVRMSSIGAGTLLVQEGLEPIIQMTCRDRNRLAIQSDLLGAYALGMRNLLCLTGDHQ
SFGNHPTAKNVHDIDSIQLVKMVVDMRDKACFQCGDEIKETPPRFFVGAAANPFGDPFEF
RPYRLAKKVKAGADFIQTQLIYNVERFAKFMEKVRELGLHQQVYILAGVGPVKSPGMARY
MRDQVAGLDVPDEIVDRMTRATDGIDESDKKGRRDAWRNEGIQITIDLIQQIREIEGVVG
VHIMAIEWEEAIRPIVEGAGLLPRPEPA
>A0A2D9QIL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSEKYQQLRDVLESGRFAITAEIPAPVSASSVEMEEKIKILKGSVHAINVTDNPGATAHM
SSLAGSAIVRNQGIDPILQITCRDRNRLAIQSDLMGASALDINNVLTLAGDPVKNGDQKD
AKAVFDINSKTILSIMDVMNAEGKTMSGKELQTKSNFFPGGAAILHEPEENWEPKALNEK
ASFGARFIQTQFCYDVELVKKYMQRIVETGLSEKLYFIIGIGPLRSDKSAKWMRDKLFGT
VMPDSIVTRMESARDQIQEGINICAELIESFQEIEGVHGAHLMAPXNLSAIPETVKRSGI
SI
>A0A1F4A1C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_64_12|TrEMBL
MKAKSTSSESAEGSIGQLERGLRQGLFTVTAELTPPVSTNPEEFIRRGLTLKGLAAAVNI
TDGAVAKAHLSSLVAAHFLIRNGIEPILQMTCRDRNRIALQGDLLGAVALGVRNVLVVHG
DDPKREGTAICVEILQQLAATPGIAGAHIMAPQFFSAVPEVIAASGVTGKMRAALPR
>A0A2D8QNZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTIIESDPKARRNYIRKLLSNASIEALPAQVITTPEIVQPLPSAPVFVPFLPGSDLDSTI
IATRNLVSMGREVVPHLPARSFQSRDHLSDWLAAIRSTDTKHLLLIAGDTQFPLGPFKDT
LDVIDTGLIEQHDIERVFIAGHPEGHPLVAPKVLYDALTVKHAWSEAMSIELHVVTQFTF
DIPQFINWLDQVNQITNSIPVHLGIAGPASPASLAKYALQCGVSLSGKMMLSNRSARKLL
TQWNPSALIEDLMRFYPVSRPAAIHIFPFGGISKTSEWIKKMTLFPKAKPVY
>A0A2M8R253|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium forestalis|TrEMBL
MSGAMTDPTTPAQSDGQDGHLKRPAISFEFFPPKTEEMERNLWDTIKRLAPLEPKFVSVT
YGAGGSTRERTHSTIARILQETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRG
DPVGGIGTPYASHPEGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKA
KVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTV
PDWFAAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLG
IRAKSAQKAA
>A0A2D8QNN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MRERLFSFEYSAPRTNEALEKLKKTHYRLNPLKPHFCSVTYGAGGSTKEGTQQAILELSS
GSTPMAPHLSFGNDPLLXIDELLKTYRSAGVSRLVALRGDRPSGILGGNAMTHANELVQY
VRETTGDHFHIDVAAYPEIHPESETVESEIHYFKAKVDAGADSAITQYFYNPDSYFRFRD
LCLKAGVNVPIVPGIMPITNYEGLLRFSSLCGAEIPRWLDKNLKSLKHDKDSLRAFGADV
VSDMCQRLLDHDAPGLHFYTLNQAMPTLRIWNNLRLS
>A0A7C8BX75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adlercreutzia muris|TrEMBL
MEPVASLFAPRSIPFSVEMFPPKGSLTLDAARKVVGGMALARPDFISVTCSAGGSGNGGQ
TIEVASLIQSEAHIPAVAHLTCVNSTRETVQAAIAELKAAGITTVLALRGDLVGNAQPGD
FRHGADLIPLLKDAGFCVGAAAYPEGHLDCLDLDEDLRHLREKQDAGADFFVTQLFFDNA
DFYRFRERALAAGVTRPVTCGVMPFLGKSQIQRMVFLCGSSLPSPIVKLLAKHEDDPAAL
RAAGVEYACRQLVDLARNQVDGVHVYSMNHPDIAQAAATALADAGFRA
>A0A317G3I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio fibrisolvens|TrEMBL
MTFENYLNNKIMLADGAFGTYFASKYGTGALPECANITDPSKVIDIHSDYIKAGANLIRT
NTFACNTLNLGPDMKKLGDHISAGCRLAFMASSLYSDTSDIQDSNTGIPNPGISYTDKSG
SDENSDARINDTNAANQGKRQIFVAGDVGPIPFIPGQDDEKISEEYFFMVQTMYNSGIKI
FLFETFAGIDNILKSLNWLKEKKENEPDLFVWVQLCSNQHGYTNEGIHVRNIIKELSEKK
LVDAAGLNCGIGPASMRNILDEIDFTGIKYVSAFPNASFPQGMLSRPIFSGNEKYFASKM
EEILSLGADIVGGCCGTSPDYTSKIAELDLSTKKIHAFKGEADLSIKVREKDSSFWEGKT
SKKLIAVELAPPFGADDKKLMDSANALTKYNVDAITLPDSPSGRTRADSILAGLKVTTET
GIATIPHICCRDRNIISLRSGLLGAYMNGIRNVLAITGDPVPTLMRQEAKSVFNFDSVGL
MKVLAELNREEFYKDPITYGGALSYNRPNTHVELSRMIKKIEAGASFFLTQPVFSDEDIE
KLSFFKDKMKEVNSDVKLFCGLMPLVSYKNALFIQNEMSGINVPDEVIARYKPDMSREEG
EMVGVSVVRDVIAKTKDFSDGYYFSIPFNRVYLLDKILD
>R7IQE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:303|TrEMBL
MKIQEAVKNRILLLDGAFGTYFKSMHYDFENADYPEKATLEHEDWIVRIHKEYIMAGADI
IRTNTFGINHGICQSREEMRILIEAAVAAAKKAVSESGREVYVAGSIGPIKYASEKEEED
AYEEYCYLIDTLYENGINIFVFETLSDIDMAQRLAAYVRNNIPEAFITVQFVFNKMGYTK
YGYNLQRLVDRLSEDNNIDVFGINCGIGAAHMCELLEKVRFRKECKISVLPNAGYQQDLI
GRDMYFHNAGYYMEYMKKMLEMGVNMIGGCCGTTPEYTKKMRTLLDEHPQVQEKKMASQE
EKEQRITETNPFMEKLNRGEKVYVVELDSPFGKSADKFTEGAFLLKENQVDMVTISDSPM
AKARADAFEMAIYVQNKTGLTMMPHIACRDRNAIAVHAAFLGAHINDIRNLLIITGDPVG
REDRNVISPVFDFNSVKMMQYLKNMNEEIFQDEPFYYGGALNYAGANVNAILAKMQRKMD
AGCSYFLTQPVYSDEDIQRVRYLKEMTGAKILCGIMPLVSLKNAKFMQNEMPGIHVPDEI
VNRYTADMKREEAEKTAVDICIGIGQKMQDFADGYYIMTPFHRVTLVNKIIQGLRNTDAE
NGQD
>A0A1Y4IV03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmiger sp. An194|TrEMBL
MRLSQVFRQKECVFSIEVFPPKKNGATPESLYPTLEKLAGLSPDYISVTYGAGGGKAGLS
TVQIARHLKQELGVEPLAHLTGINSTREQVAETVQALQDAGIENVLTLRGDICPDAPRSK
DFFHASDLATFVKGKGDFYLAGACYPEGHVESETLRQDVENLKYKLDAGVEHLVTQLFFD
NARYYRFMNLVRKAGIQAPVQAGVMPIVSARQVQRTVALSSASLPPRFTKMISRYDGDDA
ALFDAGINYAIEQLRDLIEGGADGVHLYAMNNPEVARRVYEGIRDLLPEAKA
>A0A1Z8VEJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium TMED61|TrEMBL
MHSATSDPGQPLSILQGHVSPGRLERVLRSGKFAVTAEIAPPDAADVEAVYQRASAFDGC
VDAINATDGSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVTN
ILCLTGDGVQAGDQPDAKPVFDLDCISLLQTVTVMRDQGEFLSGRKLTTPPRVFLGAAAN
PFGPPLDYRPVRLKKKINAGAQFVQTQYCFDLDRLKKYMTQVRDMGLTERCYILVGVGPM
PSARTAAWIRDNVPGVHIPDSVIKRLLSARDPREEGVRICVEMIQAVREIEGVHGVHIMA
YKQEERVREIVGESGVLEGRMPWYPGVDNDQQGQQT
>H0QVB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia effusa NBRC 100432|TrEMBL
MGLADRIAGREDGLLLFSITPPRRSTSPEEAQRIADVTIERLQAVDVDGLILYDIDDESD
RNPNERPFPYLPTKDPAAFYEQHLGGWEKPVVVYRCVGKYEESELTDWLAAQDPAKVLTT
FVGASTGGKVCRTDLPSAQKLWHEVAPTMRLGGVAIPERHSHSGGEHSRLIRKQQAGTSF
FVTQVVYDTSAAKSMVSDYFYACEDAGLKPVPVIFTLSVVGSMKTVEFLEWLGVDVPRWV
RNDLSHAPDPLATSYDQCILAARELTSFCEHLGMPHGFNVESVSIRKAEIEASVRLASHL
RTRRLR
>A0A5S4HCD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura geliboluensis|TrEMBL
MTGKDAGALVDAAGLIPPGTRVNVTFLAGEDLATRVSAARAVRERGLRPVPHISARRLRS
ESELAEYLSALAEVGAAEEICVVGGDPARPAGPYADALAVIRSGALARSGVRHVSVAGYP
EGHPHIDTPTLWCALEEKHAALYRQSLGATVITQFGFDPAPVVAWLDELRYRGVDAPVRI
GVPGPAGVKRLLRYARRFGVQSSAGIVQKYGFSLTNLLGTAGPGRFIKRLQEQIDPVRHG
DVSLHFYTFGGIRVTAEWVRDDESMVTQ
>A0A1G1BIS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melioribacter sp. GWF2_38_21|TrEMBL
MKVIEHLYKAKNPLISFEIIPPKRGGNVRQLLHVLDDIVKYNPPFIDITSHAAEVMYEET
SDGGMQMKVKRKRPGTLGLCALIQNKYNIDAVPHVLCSGFTREETEDFLIELHYLGIDNV
LAVRGDDSAFKKPLKFGRSMNEYAVDLVKQINSLNKGKYIEDGLLDAEPMDVCVGVGGYP
EKHFEAPNLATDIKNTKEKVDAGASYIVTQMFYSNKFYFNYVDQCKKEGISAPIIPGLKV
ITSKAQIKSIPKNFFIDIPQELAEEVEAAKPEHVMEVGVEWTKKQVEELLNKNVPAVHFY
VMQNSQPIKLLMNKLKL
>A0A3A5RHX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AM32-11AC|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIREVAKQIY
>A0A059W0C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albulus|TrEMBL
MRDLLASGKRSFSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTAELRNIIGQYADAGIRNMLALRGDPPGDPMGDWIRHP
EGIGYAAELVQLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVDKCRAGADFAITQMFF
YPEDYFWLRDRVHAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAARILAVKDDP
AAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQRP
>A0A3R6MPT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium AF42-6|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGKDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKAAEI
>A0A417W2N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. OF13-6|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTSSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>A0A6N8JIZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga oryziterrae|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYEHLDPLMEFKPAFINVTYHRSEHMFKKK
SDGSFDKVEIRKRPGTVAICAAVMNHYNVDAVPHLICGGFSREETENALIDLNFLGVDNV
LVLRGDAPKNEASFEPEPHGHRYADELLQQVVHMNNGIYLEEDLQGGVKTKFCIGVAGYP
EKHFEAPNMQTDMKYLKRKVENGADYIVTQMFFDNQKFFDFVAKCREAGITVPIIPGLKP
ITSRKQLNILPRTFHVDIPADFSNEILKCKTDKDVEELGAQWLIQQSKELKAFGVPVLHY
YTLGKPNVILKAIQAIS
>A0A1A9ND19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia ginsengiterrae|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRTQLALLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
DGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQARSPRHDLENFARKVKAGANSAITQYFFNADAYFHFVD
DVRKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCGRLIDAKVPGLHFYTLNGAAATKAICERLGA
>A0A1V5S5V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin300|TrEMBL
MKTIELFKKKTVLSFEIFPPKRTNPVDTVYDTVERLKDLKPDFISVTYGAGGSESNADTL
KIASAVKNDYGTESVAHLPCVNLTKNDVLEMLGKLKRAGIENILALRGDVNPDFAPKNDF
KYASDLISFIRENGDFNIIGACYPEGHFEASSLIEDIRNLKKKTDAGASHLITQLFFDNG
YFYSFRERAVIAGIDVPIQAGIMPVVNKKQIERMVSLCKVDLPKKFLSMMTKYENNPSAM
RDAGIAYAVDQIVDLLAQGVDGIHLYTMNNPYIARRIYEAVSSLID
>A0A2W7BWD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium kowhaii|TrEMBL
MIGGQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEQCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A3N0UZY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomethylobacillus aquaticus|TrEMBL
MKSVPVISFEFFPPKTAEGQAKLREARRQLALHQPKFFSVTFGAGGSTRDRTMETVLEIR
SEGFDAAPHISGISSSRDEIRQLLDAYQQHDIHHLVVLRGDLPSGEASVGDFRYANELVS
FIREHSGDWFNIEVAAYPEFHPEAASPAADLANFKRKVEAGANSAITQYFYNVDAYFGFM
EQCAGAGITIPVVPGVMPIYNYTQLARFSDVCGAEIPRWLRLRLQEYANDLPSLRALGMD
VVTDVCERLLAAGAPGLHFYTLNQAGIISTILQRLPLPAAR
>A0A3N2RBC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter enzymogenes|TrEMBL
MLPISFEFYPPKTDDQRSQLDKTATKLRGFSPSYVSCTFGAGGSTLSYTPETIRRLRGKH
GLDAAPHLSCVGGTRGEIRQLLELYRELGCRRLVTLRGDLPSGMASAGDLRYANELVEFI
RAETGDHFHIEVAAYPETHPQARDALSDLENFKRKVRAGADGAITQYFYNPDAYFRFVDD
VRAAGIDVPIVPGIMPIANFSQLRRFSDLCGAEIPRWIAQRMQAYGDDADSIREFAADVV
ARLCSRLIEGGAPGLHFYTLNLAKPTLSVLARIA
>A0A2J8KXD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pan troglodytes|TrEMBL
MGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSL
CQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPI
FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEEL
TSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQ
PNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKG
ENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPS
RSIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELVNRPTQNARETEAP
>J9VZ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus buchneri subsp. silagei CD034|TrEMBL
MSLTALFKQKTVFSLEVFPPKKDSPTDAILPTLKRLQSLQPDFISVTLGAGGTNHCDGTV
AVADLIQNQLNIPAVSHVPGLYQSKDQVLALLDRLDQIHVKNILALRGDRIPGKEPVGDF
NHANELVKFVHEQRPDFSIASACYPNCHTEAADFVDDISHLKEKVAAGADHLISQLFFDN
QAFYDFKEKTEIAGINVPIEAGIMPCTNKNQIERITQISGVPIPKKFAAIMDRYQDSKEA
MLDAGIAFAVDQIIDLVSQGVDGIHLYTMNKSKIAKRIWEETESVFAASNLAKQKANQN
>A0A2T7VGI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. TPD3009|TrEMBL
MTISVNQLEEAQVALGAPLYADVGGDLDVSFEFFPPKTEKMDEQLWEAVRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATKAEIDQVAEEYWAAGVRHIVA
LRGDPPAAGAKFESHPGGYENAAALVAGLKRLHPFEISVAAYPECHPDSVSVAADIDNLK
AKLDAGATRAITQFFHEPETFFRYRDKVAAAGITAEIVPGIMPVTNFASVVRMSKMCGTE
VPAWLARLFDGLEDHPAARQLVAATLAAELSRKLYAGGVKSLHFYTLNKAELSFAICHLL
GVRAKPVQDAAAA
>A0A852W7S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia antarctica|TrEMBL
MTTTFASTVTERINVDRPFFAVEFFPPKDDRGEAELWRAIRRLEVLDPAYVSVTYGAGGS
SRDRTVRTVERIATDTTLCSMAHLTAVSHSTDELRHVIGSLAAAGVRNIMALRGDPPGDP
LGEWVAHPDGLEYADQLVALIKRSGPFCVGVAAFPYGHPRSAELETDTERLVGKFRAGAE
FAVTQLFLEPDGFLRLRDRVAAAGFDQPIIPGIMPLTSEKTFHKGPELSGSPLPAALVER
LAPYSGDTAAFRAAGMEVTGELCERLLAEGVPGIHFYCLNRSTATTELVERLGLAPRHEG
TRLSTPA
>A0A1Q7RY72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_40CM_2_56_11|TrEMBL
MQDLLTRLENHVLVCDGAMGTMLYSKGVFISRCFDELNISNPELVREVHLDYIKAGADII
ETNTFGANRTKLMTHGLADQIRHINIQGARIAGDIAGDNILVAGAIGPLGIRIEPWGKTA
IEEAQVTFREQAKALVDGGVHALILETFFDLNEVYAAIRGVRDVTDQPLIVQMSIEEDGN
SLEGTPPEVFAKRLEEWGADVLGLNCSVGPQIMLDAIERIANVTSKKLSVQPNAGKPRNV
EGRNIYLGSPEYMASYAKKFVQYGVRIVGGCCGTTPQHIKAIRAAVKSVGVAVLGPSPGA
SRRPLPAGEGTEGESSIPLESRSRLGRKLATKEFIKIVEMIPPIGHDFAKAIEKAKYLQA
QDVDAINVPDAPPSSARMSAISLAVLLEKSTEIESLAHYTCRDKNLLGMQSDLLGAYALG
LRNLLLITGDPHQIGEHSDATAIYEVDSIGLTNMVSRLNGGVDVGGKSIGKPTGFVIGVG
ANPGAMSDLELKRFFYKVEAGAEFVLTQPVFDATVLERFLDRAGNSKIPVIAAIVPLPNY
KTAEFLNYEIPGCSIPDSILERMREAQSKSPEHARNEGILIAQEILERIHGTVQGVQIRG
PFDRYETPVEVLSVPMKGATR
>A0A8J3CHE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Longimycelium tulufanense|TrEMBL
MFSVEFLPPRDADGERQLWRAVRELEPLDPAFVSVTYGAGGSRRDRTIRVTGRINQETTL
VPVAHLTAVNHSIAELRNIIGWYAAVGVHNVLALRGDPPGDPMGEWVRHPQGVTYAEELV
RLVRELGDFCVGVAAFPYGHPRSIDLDEDTRFLVRKLRAGAHYAVSQLFFDVEDFLRLRD
RLVEHGVDVEQVPLLPGMMPITSLKGVQRMAHLAGAPVPATVTERIERYADDPAALRAEG
VDIATEMGRRLLDEGVNALHFYTLNRSTATREVVARLSLVPSRA
>A0A512FIK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus paraplantarum|TrEMBL
MKLKQALQQRILVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIQAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAVTAREHADHPVYILGTIGGLAGDTDATIQQ
ATPAMIAASVTEQLTALLATEQLDGILLETYYDLPELLAALKIVKAHTELPVITNVSMLA
AGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPTNVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSSRSIVAHNQ
PTAKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTMIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TAVSTKSISRKLSYGCDYIITQPVYDLANVDALADTLAANHVDVPVFIGVMPLVSRRNAE
FLHHEVHGIRIPQAILDRMAQAERTGHERATGIAIAKELIDGICACFNGVHIVTPFNRFK
TVIELVNYVQAKNLIKVQ
>A0A8A5P665|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MIRKRTKFKLHDISTSPAIAASIEASPAQVLGPASLAGIFPQGVRVYLTDTGQASQDRLV
DAAKHLRDLGYTPVPHLAARRISFRVQFEEQVKRLAGEAGVSDVLVVGGGVATPAGPFAS
SMDMLSTGIFDRCGINQIAIAGHPEGSPDFSDETATAALKLKYDFAERSDAAMRIVTQFG
FDPARFIAWAEGLAASGIDLPVHIGVSGPARITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESVVGPIERHWQANPAGPIRQIHVFPFGGLQNSADWLAGRGSWQIGDADFSAK
RGTVAI
>A0A1T5APU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizorhabdus histidinilytica|TrEMBL
MTRGFPMATTMRDEAWPVRERIVAFARDASFELSPRDGAALAAAASLAPGSRVSITWLPR
DADDDRVAAARALHDRGLVPVPHIAARMIEDEAHLAGLIGRLCGEAGVSQLLVIGGDAKQ
PRGPFAASTDLLSSPALAHPMVRRIAVGGYPEGHPWAGEALLDAKIAAIGALGVTAEVIT
QLCFDSGPILAWARVFRARHPEVPVRLGIAGPASIRTLLRYARICGVGNSAKALVARGAS
IARLLAEAAPDPLLRDLAETPDIDALAPVGVHLFPFGGFERTARWIGAVAEGHFRFRGSD
SGFQVDPAG
>A0A330GUG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium atlanticum|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFVDFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>A0A2S8QRB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus luminescens|TrEMBL
MNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSINRLSTLKPKFVSVTYGANSGERDRTH
SIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGDLPENGEKPKMY
GVDLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGANRAITQFFFDVESY
LRFRDRCVTAGIDVEIVPGILPVSNFRQLKRFAVMTNVRIPSWMTRMFDGLDDDPESANL
VGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A2G6R7N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Draconibacterium sp|TrEMBL
MKVIDSIKNADKTVFSFELLPPLKGKDAERIYQTIEGLVEFDPKYINLTTHRDEVEFKEM
ADGSIVKRVVRKRPGTVAIAASIQHRFGIPVVPHILCGGFTKSETEYVLIDLNFLGIENV
LALRGDGEKNQHVFRATPNGHANANELVNQIRELGKGNYLEEDLKNNKPLDFCVGVAGYP
EKHFEAPNMESDMRFLKQKVDAGADYIVTQMFFDNQVYYNFVEKCRENGINVPIIPGIKP
INLKNQFTVLPKIFNIDLPKDLADELRKCKTNDDARQVGTEWAIYQSKDLVAHNVPSLHI
YTYGVSDNVKDIVKAVF
>A0A1B9UV61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MLRSETARQNGEIRGDIRLSFEFFPPKNPEMENQLWETVAELKKWDPDFVSVTYGAGGST
KAPTLDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIG
TDYRPHPQGYENAAALVKGLRDISDFEVSVSAYPEKHPESASDAVDIDMLKRKADNGATR
ALTQFFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPSFLDERF
AGYDDDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSA
A
>A0A2U1EDE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora cinnamomea|TrEMBL
MSALREALAAGRFAVTAEIGPPRGADPTVITRKAEHLRGWVDAANVTDNQGAHVRMSSLG
GSVLALRAGVEPVMQVTCRDRNRLALQSDLLSAAALGVPNVLLLTGDHPRYGDHPDGKPV
FDLDGVQLVWTARTMRDERRLLSGRELTAPPSWTVGTVENPFAPPVGFRARRLLKKAVAG
AEFVQTQFVFDVPRFAAFMSEVRDLGIPERCAVIAGVGPLRSVRVLEHVRDNVPGTHVPD
ALARRLRGVPPARVAEEGVTACVETIQAVREIPGVAGVHVMAFGFEHGIPDILTRSGLGR
ADRSQADHTEGAVPTTVLPGGAHRAG
>A0A1G5RH54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus luminescens|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSINRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLDAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGD
LPENSEKPKMYGSDLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQLKRFAVMTNVRIPSWMTRMFD
GLDDDPESANLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A1H6SSR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. AP50|TrEMBL
MFSDILSNYSIEATAKDAATIVIADNLPCPAQVYVPYLPEESDAARIDACAMIRAAGLLP
VPHISARRLQSEVALDALLGALRDQAQVDTIFLIAGDLARPVGPFADSLSVIATGLIERH
GIKSVGIAGHPDGHPDVAEDVIWQAMQDKVAALTARGLDSQIVTQFSFDAQRVLDWLRQV
RARGIGQPVRIGIPGPTGVRTLLRYAARCGVTASAGAVAKYGLSLGRLFGNAGPDRFVAD
LQAGLEPTRTGQVHLHIFPFGGFAQTADWLVQAGAAPRGCRAA
>A0A2M7L2B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium CG_4_8_14_3_um_filter_66_20|TrEMBL
MADVQEAEQEVTDPASAAGPVSKLDAALKAGEFVVSVEVVPPRIPSFAALDKVVEAIESV
AVGVNVTDFAGANVRISGAMVCKYLLEKGVEPIFQMTCRDRNRLAMQGDLLGLLAQGLRN
VFCVSGDYISLGDHPEAKAVYDIDSVNLIKMYNDMRTKGVFANGDLIRETPKTEHVIPKF
CLGGACNPFADPFEFRVDRLAKKAAAGADFVQTQCIFDLDRFERFMKLVCERGLHKQIKI
IGGVMPCKSHRPLLYMRDNVPGVRIPDEVIKRLEGAEDKKAEGVNIAVETVQRLRNMEGV
AGIHIMTLSWEEVAPILVERAGLDKLN
>A0A2W0FGC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. TKO29|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLAGYNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLQQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A815JA45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sordida|TrEMBL
MTLTHTEKNTASNHCHIHENGIGAPKICHSLDNFSELKRSESEHTCLTVKGCSLHPVKYI
SLKEKLQKRISNNDRWYSLEFFPPRTTNGAVNLIGCLERMAVGEPLFCDITWHTAGDPAG
TKETSTMMIANTMLNYCNIDTMLHITCYGAKKATMIEYLSKAKDFGIRNLLALRGDPPVG
EKWNPEKTDFRYASDLVKFVREHFGDYFVICVAGYPKGHPDSKSYEEDLGYLKEKVDCGA
DFIITQLFFQAETFLKFVSDCRAVGITCPIIPGIFPIQAYASFKNIVCLTKLDVPDEITA
YMESIKDNDEAIRNFGVQTCVDLCKALLNSDKVHGLHFYTLNREYATTEILKQLGFGFDD
PPLRALPWKKTSKNYVRSKEDVRPIFWSTRPKSYIHRTSNWNEFPNGRWGISSAPSFGVL
TDYHLFYMKIDATRDELLDEWGHELTCEQDVWKMFACYIRGEKNGSDKIVRHFPWKDEEI
SLETHLIHNELIEYNRKGILTINSQPAVNGKPSTDSIFGWGERNGYIYQKAYLEFFTSAN
NIPALRAVLKNFPGVNYHFVNKSGDVNETNTDHEQPIALTWGVFAGREIIQPTVVDTVSF
MIWKDEAFSLWMERWGKLYEPGSSSYSIIEQISNTYFLVNLVDNDYPQGSCLWAVLDAMF
EYQQKTNQDINHS
>A0A6N0LI48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 10FS3-1|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKLQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFTIEVAAYPEMHPQAESFDQDIQRFCEKANAGANAAITQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDTASIRAFGHE
VVVKFCERLIAGGAPSLHFYTMNTTDPTLQLVKDLGLA
>A0A1F2ZJ43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. RIFCSPHIGHO2_12_41_5|TrEMBL
MSLLAQYFAQQQFCVLVEYLSAHQAQWSVKTEFVGFPAAMTLADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDAKTQGQKNLLLLTGDKLKQHRHSHDLEPRTRYL
ESVNAVMEAKRQGSFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMTAL
QDAHAFLARHQYALKILACVMPLTLARAKFMLKHKVAGIVITPHMLQVLQQEKEQGLSDR
VYVRCALQILMCRHLGFAGVHLSACHQPEEQSLLESYIEEYRHLSFAECERLWNSLWQVQ
TGTEFHPKLTYYSRPATSSQIIKYQHLHLMHDALFESKLAKGMGRFIFNFNVWDRSRAKQ
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTKILQEKLIPTVSIAVRGTSSWKNWYVEAAG
>A0A8J8HQM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geothrix sp|TrEMBL
MTHPTFQQALDAGECFLFDGSTATALHDRGITLQRSFEECNLKSPDLLLAIHGEFLAAGA
QVLTTNTWGAGRLKLAARGLDGELDAINRQGVDLAKRAIAQQGARAWVAGCIGPLGVRIE
PWGPTSFDEARALFREQATPLIEAGADLIVLEGFEDLNEIHQAILAVQEAGQLPIAALMT
TNEDGQALFGAEPDWFIKQLDTWGADMVGLIGGNGPAPHLRLLEKLKAVTAKPIVLQPNP
GLPNMVDGRLIYGASPEYLGGFAGRALAAGARAVGGCSGTTPAHIRAMRGAFRQERAFVQ
GGGGFELKPHEQPQPEVPFAFRSRFSLKLAQNEFIHTVELVPPKGMEYDKLVAKTRQCRA
LGVDAINVPDGPRAMARMSALATALIIEQQVGLETILHYACRDRNLLGMQSDLLGAAGLG
LRNILAVTGDPPKLGPYPQATAVFDVDAIGLVNMLKRLNTGLDLGGASIGKPTSFSVGVG
ANPVAADLEREKTRFRYKVEAGAQWAITQPVFDAESLFRFLDFTEALDGKGGLPIIAGIW
PLKSLRNAEFMANEVPGAYVPPTVLTRMAKWSTAEDQIKEGLAIAQEVIDAIRPRIRGLQ
LSAPFGQVELVAPLLPKPEAPW
>A0A448YMA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brettanomyces naardenensis|TrEMBL
MSKITDKINQLSADEPFFSFEFFPPKTEHGTRNLYARLGRMSLMGPLFVTVTWGAGGTTA
EKSLGLAITCQKELGLTTCLHLTCTNTTREVIDEALHAAKANGIRNILALRGDPSREASA
SHGLGEFEHAVDLVKYIRKQYGNYFCIGVAGYPEGHADGFYDASQNPKKDMPFLVEKINA
GADFVLTQLFFDVDSFLSFNKLLRSQPDLRNKDITVIPGLMPINNYGVFQRATKLSHASI
PDSVLDRFDEEIQNDDDKVKEIGVSLINEMIKEIYEKTDGKIKGFHFYTLNLEKSIAQIV
NQSPILSKVVEKKEKELEQCVSDSSDDDIDDSTTTAKRAAYMNRFKQPTNQIIVDSKKDL
IKSAKMAAGQAQQYRRSSSSQFQKIMSISSGHGTLGKDATWDDHPNGRFGDTRSPAYGTS
SYGPSLNVTSVKAYELWGQPADLDGISNIFVSYLSRQIDSIPWNEMSINPETAVIQEQLI
ELNKAHMFTMSSQPASNCAGSNDKIFGWGPSHGYVYQKAFVEMFVSKEDWEKKLLPKLKD
NPEVSYYVGDNRKYFASSMKAQDTNCITWGVFPDRQIVQTTIVGEDTFKAWKEEGFEIWR
EWMLLYPRGSPSANVIKNVLDNYYLTTIVHHNYPDENALWRLILGEDED
>A0A2H1XT72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum dicentrarchi|TrEMBL
MKITKHIEKSKGKTLFSFEIIPPKKGNNIQDLYNNIEPLMEFNPPFIDVTTSREEHLYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFSKEETEYLLVDCHYLGIEN
VMALRGDAMSHQRYFEANKDGHQYAMELVGQIQNLNNGKYLHDVIEANHKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVEAGADYVVTQMFFDNQKYFEFVKQARKMGITVPIIPGIK
PIAIKRHLQLLPQVFKIDLPQNLITEIELCKNNQQIRELGIAWAIAQSQELLKAGVPVLH
YYSMGKSDNIKAIAKALF
>B4X3B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp. DG881|TrEMBL
MKRISFEFFPPKTEQGKEKLLATQQKLQVKNPEFFSCTFGAGGSTRDNTRDMINKLREQH
GDTAPHLSCIGQSRDEILELVNGYKAAGVTRIVALRGDLPSGMGYAQSEIKYADELVQLI
RQETGDHFTLEVAAYPEMHPQARSFEDDIAHFKRKVDAGANSGLTQYFYNADAYGYYMDA
LHKAGCDAPVYPGIMPILNVANLLRFSSTCGADVPRWLQSKLNDIKDDDVAVKAFGEEVV
TRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGM
>A0A418Q479|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas edaphi|TrEMBL
MNRETQVALAEHAPLFAEARGDIAVSFEFFPPKSDAMSETLWKSIKTLAPLRPRFVSVTY
GAGGSTRERTHATVERLVRETSLTPAAHLTCVGASREEIDDIARSYWDAGVRHIVALRGD
PAEPGQPYAAHPGGYANAAELVTGLKQVASFEISVAAYPEVHPDADCPDSDLDNLLRKID
AGADRAITQFFFSPECFFRFRDKVVARRPDVEIVPGILPVTNVAQARRFAGQCGAAIPVW
MDRLFEGLDDLPAARQLVAATIAGELCGQLYAGGVRHFHFYTLNRAELAYAICHMLGARA
>A0A083ZVX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. DD3|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLVAAPHLTCIDATPSQLIDIATDYWNSGIRHIVALRGD
LPPDSGKPEMYAADLVTLLKSVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMSSMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A345STQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptacidiphilus bronchialis|TrEMBL
MALGIPSTRTDRAVTVRDLLAEGHRSFSFEFMPPRTEQGERKLWDAIRRLEALAPNFVCM
TYGAGGKSRDRTVDMVGRIASETTLTPVAHLTAVDHSVAELRNIIGHYADEGVRNVLAVR
GDPPGDPMGEWVPHPDGVRYASELVELIKGIGDFCVGVAAFPEMHPRSATWEEDIRHFIA
KVRAGADYAITQMFFHVEDYLRLRDRVAAAGCEVPIIPEIMPVTNVKQIDFFARLSNAAF
PAELAERVLAVADDPAAVRAVGVEYATGMAERLLAEDAPGLHFITLNHSTATLEIYQNLG
LHERV
>A0A1V4ASX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Brocadia caroliniensis|TrEMBL
MKSESNLEKILRSGHFAVTAELGPPRGADRSVIEKKAGLLKGYGDAFNITDCQTAVVRMS
SIAAGRIVLDAGLEPIIQMTCRDRNRIAIQSDLLGAAALGAKNLLCLTGDHQKFGDHPMA
KGVFDIDSIQLIQMVKTLRDEKKFQSGQDLKASEPRFFIGAAENPFADPFKFRAIRLAKK
IAAGADFIQTQIIYNVKKFQEWMKMVTDMGLHEKAFILAGVAPLKSAGMAKHMKHNVPGM
DVSDEVINRMTAASAAKKGKEEGIRICLEVIEQVRETKGVAGVHIMAVEWEEAVPEIVQQ
ARLYPRPVL
>A0A5B0N077|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia graminis f. sp. tritici|TrEMBL
MAQDDPPKGQKILSVRELNPGHPRDKRGLTNLYDRICRMSQLGPIFIDITWGAGGSTSNL
TTEFVKTAHEQFGLETCMHLTCTNMPKSKIDTALKEAYEFGCENILALRGDPPKGSTEWT
ATEGGFEHAIDLVRHIRAEYGDHFDIAVAGFPEGHMHSTLSREQQTIYLKEKIEAGANFI
FTQMFYDVDIFIDWVREIRAAGITVPVIPGLMPIQSWAQFKRVTNFSKTIVPQYFLDKLE
PIQSDDQAVREAGTKLVADMCRKILNSDLGIRILHFYTMNLERGTKMILDELNLNPSRDI
TNPLPWKMSLLGKRRSESIRPIFWANRAKSYLSRTETWDEFPNGRWGDSRSPAYGELDGY
GININAATMETLKGLKKFPTSLADLARIFANYCGARFPGEEPVKYLPWSDIPLSEETNKI
EDVLVKINKRGFLTINSQPAVDGAKSSDPVHGWGPRGGYVYQKAYLEFFCCPEKFQSLTE
RLEKDPDVTYYAVTKTGDLVTNNTRPGPNAVTWGVFPGKEIVQPTIVELVSFIAWKDEAF
ELGHQWAELYKEIAPESARFIHQIMDSWYLVNIVNNDFRKSNDDSEHSALFQFFGPEPVI
VDQDDLPPTTNGLSHPNGLPKTNGSSSPAISEVNGELKNLAI
>A0A0R2B0J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus ozensis DSM 23829 = JCM 17196|TrEMBL
MSNKMFSIEISAELNQIQLIKHYLGKWKPSFVSINNLSETKFEDVVQITNYIKKDLGIPV
LVHMSGISKTKDEIVKELKTMEKYGIHRVLALQGNLYHGIKIKKDFQYASDLVKFIKSYD
NSIEVFGTCYPEKHPKAKNLESDIEHLKIKVDAGAIGLISQICFDNQKVYQFINKIREHG
INVPLFSGIMPITKEYQLHWLEHNKISTHNSFDNVKDLDQYGINFSIKQINDLLMHNVDG
IHLYTMNDWQTTDAIYDKIKHNFK
>A0A7C8M0B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massariosphaeria phaeospora|TrEMBL
MEKVTDKINALPEGANYFSLEFFPPKTSMGFANLQVRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRALIDEALEQAKVLGIRNILALRGDAPRSEE
YRDDTQLPEDDSNKDFTWAIDLVTYIRKQYGDYFCLGVAGYPEGHADESHPEKQDPKFDL
PSLIDKTKAGADFIMTQLFFDVEAFDSYEKMLREHESGVFKTIPIIPGLMPIQSYQILRR
TSKLSHARLPEGLLARLDAVKGDDELVKQVGVKILSELVDHIKPRPSVARRGFHFYTLNL
EKVVSHILESCHLIPPTLIAEDEEAIATTPAINLSPPNGAVSNGDRLRPASFNSSPHNQV
IISHPAVSKSSHASFETPEAEAGIPKGPVNTRANTLAISEGEGSLGREATWDDFPNGRWG
DARSPAFGEIDGYGPTLHVSTPQALKFWGHPVEAADISDIFKRHIGGELEAIPWSEQGLS
PETNIISKQLLGLNEKGWWTVASQPAVNGVKSTDPVFGWGPKNGFVFQKPFVEFFIPSSD
WAKLKPRLEAHEQITYFAGNADGEFEASSEDGVNPVTWGTFAGKEIVTPTIIEEVSFRSW
LEEAYSIWKEWQRIYPANSATSKLLGTTRRDVWLVNVIWGDFVEGEGLWEFLME
>A0A7J9WB18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitriliruptorales bacterium|TrEMBL
MQHPVKELLARDGPSFSFEFFPPKTDDGERLLWTAIRELEPLQPTFVDVTYGAGGGTRDR
TLSVVKRIAAETSLTVVAHLTCVAATVEDLQATIADFADAGIRNVLALRGDMPGGPQATW
EATRGGLAHADELVRLLHGEGDFCVGVAAFPEGHPESPDRETDAKYLAAKCAAGADFAIT
QFFFSAADYLELLDRVADLGCDVPVIPGVMPVTNVSQIQRMAAMSGAEFPQWLADRLQDV
ADDPQAVRAVGVEVAAALCEELLAGGAPGIHFYTLNRSTATREIYAQLKSVQR
>A0A1Q8WRE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MHDNEPTGPTAAAGGRAGGLSSAETGTTRRLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPADGISSGGHEGSAHESEAGRCEAVPRVRAVQEQTNPSECVLAH
VLESSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRADDVAGELRH
ADDLVRVIREVEADFFGDGRRHVTIAVAAYPATSDHIEAIEVLAAKQAAGADMAITQVFY
DAADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSTLGSASGAT
LVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDA
VDRGYLQATPGRGPSFLRRGSPGAALSSLHPVQPHTTITKENA
>A0A1F9ND75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula sp. GWF2_41_7|TrEMBL
MSELKSGSNLEKVLKAGHFAFTGECGPPKGANVAHLKEKLSHLVGMVDAVNMTDNQTAVV
RMSSWAGSILMMEQGLEPNFQMVCRDRNRLAMMSDILGAYALGVRNMLCLSGDHQSFGNH
PDAKNVHDIDSMQLIAMVKKMRDEGKFLNGDDIDVPPKMFIGAACNPFADPYEYRVYRLA
NKIKAGADFVQTQCIFNMEKFRDFMKKAVDMGLHEKCYILAGVTPMKNVGMANFMSKNVP
GMDVPESLIKRLKGVEKKDQAEEGIKFALEQIEEFKTMKGVAGVHLMAIEWEHKVPEIAE
RAGVLPRPKV
>A0A1J7GED3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lupinus angustifolius|TrEMBL
MKVIEKILAAASDPERVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEISNRMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGLQNVLALRGDPPHGHD
KFVQTEGGFACARDLVKHIREKYGDYFGITVAGYPEAHPDVIASDGLAPPEGYQNDLAYL
KSKVDAGADVIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPVDIMAALEPIKDNEEAVKAYGIHQGTEMCKKILAHGIRNLHLYTLNMEKSALAILTN
LGLIEESKIYRSLPWRRPTNVFRVREDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSGS
PSYGALTDYQFMRPRARDKKLVEEWAVPLKSIEDIYERFKLYCLGKLRSNPWSELDGLQP
ETKVINEQLEKLNTKGFLTINSQPAVNGERSDSPTVGWGGPGGYVYQKAYVEFFCSKEKL
DALIIKSKDRPSLTYMAVNKEGAWKSNVGPTYVNAVTWGIFPAKEIVQPTIVDPVSFKVW
KDEAFEIWSRGWAALYPEGDISRKLVEEVGISYFLVSLVENDFVNGDLFGVFADF
>A0A3A8B8Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius spongiae|TrEMBL
MTAPRVSFEFFPPKSLEGSFRLWDTVHALAPLGPRFVSVTYGAGGTTRKLTREAVGTLYQ
ATGLNVAAHLTCVDATRAETLAIADEFAAAGVREIVALRGDAPKGTGGFKPHPDGYSDSC
ALIEALAARGDFTIRVGAYPEPHPEAADNDADVAWLKRKFEAGADEAITQFFFSADTFLR
FRDRCAAAGIDKPILPGILPIENWPNARRFATACGATIPTWLDNAFETAERDGRTELLAT
AIATELCSRLIDEGVEDLHFYTLNRPELTRDICHALGVTPKVALRDVA
>R5YF19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:197|TrEMBL
MKVSELLKSDKVTISVELFPPKKGSQLENYKAIVGQMAELKPSYISCTYGATGGTSDYTV
EIADTINSYGIPAIAHLTCASSTKEKVQSVIKELKDRKIENILALRGDIPEDADFPLPDQ
YHHAIELIGEIKEIGDFCIGGACYPEGHPEAAAMEEDLQHLKEKVEAGCDYLTTQMFFDN
NIYYRFLYKALAKGINVPVVPGIMPVTNAAQVKRTISLTGNLVPAKFLSIVDRFGSNPEA
MKQAGIAYATEQIIDLIANGVNHIHIYSMNKPDVAGAIMDNLSEIYVRK
>B1XKT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6)|TrEMBL
MTTRLRRAIENRDFVVTAEVAPPKGGDPTKMLRMAKLLGDRVHGVNVTDGSRAVMRMSSI
AASTLLLQNGIDPIFQVACRDRNVIGLQADLMGAHALGLRNVLALTGDPVKAGDHPKAKA
VFDLESVRLLKLITKLNNGQDFNDKKMPDGPLDLFPGGAVDPQLKSWYTIESRFARKVEA
GAQFFQSQMITDFQRLEEFMNRVASQYDVPVFAGIFLLKSAKNAQFINRCVPGAQIPDAI
IERLAQAENPLEEGLKIAAEQVKIAKNLCHGVHMMAVKKEDLIPQILDLADVSIQISTAP
ALV
>A0A3C0FTY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira sp|TrEMBL
MMTVQEIKAVRKNLKVSFEFFPPKTEKMEETMWRSIRRLAPLNPSFVSVTYGAGGTTRGR
THGSVTRIQGETGIPAAAHLTCVGHTKEEIDQIARSYWNEGIRSIVALRGDLPDAGDTYE
PTPGGYAYAVDLVAGLKEIADFDISVSAYPETHPDAPSADFEIEYLKRKIDAGANRAITQ
FFFDNETYLRFRDKCVAAGIDAPIVPGILPVTNFGSLLKFADMCGASVPQRLHWRFEG
>A0A1G0JS80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPLOWO2_12_47_11|TrEMBL
MESQKKYEPKFSFEFFPPRTPEAAGKLQMTTESLAKYNPDFFSVTFGAGGSTRQRTFETV
QDIREKTGIEAAPHISCIGYLTSDIKDVLNIYKAAGIKHTVALRGDMPSGLASYGELRYA
NELVEFIRKETGDHFHIEVAAYPEFHPQAPSPKKDLENFKRKIDAGANSAITQYFYNPDA
YFRFIDSCERLGIDVPIVPGIMPIVNCTQLVRFSDACGAEIPRWILKRLQEFGDDRKAIR
DFGIDVTTQLCENLLGHGAPGLHMYTMNQSEASEAIWKNLILSKRRSEKKVSAG
>A0A2A5XKC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium MED-G20|TrEMBL
MKVVDYIKNSNKTIFSFEIIPPLKGKGIEDICEGIDPLMEFNPPFINVTYHREEYDYKKM
GNGLLKKVSVRKRPGTVGICAALMNRYKVDAIPHIICGGFTKEDTESALIDLKFLGVDNI
LALRGDPMKNESAFVPTDGGNKFAIDLIKQINDMNNGQYLYEETKNSPSNFCIGGAGYPE
KHFEAMNLKSDLKHLKEKVDAGMEFIVTQLFYDNKKFFEFEKKCREIGITVPIIPGLKPI
TNLRHLTFIPKFFNTNFPEEFSNELEKCKTNDEVKKVGIEWSTIQSKQLVKAGVPVLHFY
TMGKGESVKNIASKIF
>A0A1J5S0K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MYQARLWSVRHALALRRIYDVFQRCIPWLAPVIRLVGARSSEAVLQPLEQAAKGLLFDCR
MCGQCVLSVTGMACPMNCAKEMRNGPCGGVRADGGCEVKPDMPCVWIEAIAGGTNIAGDR
EKLPATILPPVDRSRTGRSTWLQVIRGESGPGPLPPVGAAIGHAAASFERACSSGRFVVT
VEVAPPDSADPAALLARARRFEGLVDAINVTDGAGGNCHMSSVAASAILAGQGLVPVYQI
ACRDRNRIAIQGDLLGAAALGVHNILCLTGDDVSQGDHPQAKPVFDLDAVSLLHIARGMR
DRGEYASGRKLDRAPGLFIGATANPFVPPHRDRIVNLEKKVDAGAQFIQTQFCFDLPLLE
DFMREVRARELHRRCKIIVGVGTLGSARALRWMAAHVPGVHVPEALLARIGAASDQKDEA
KRACIETIAALAGIEGVAGVHVMGHRNEQVLAEIIVESGLKRGITTTGDGT
>A0A7L0RA37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaucidium brasilianum|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTRDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPVIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>E6QML5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MLQKIFADQPVLCDGAMGTVLYGRGVFIHRCYDELNLSDPSLILAIHEEYLQSGAQILET
NTFGANRFRLGRHGLAGKVAEINTAGVRIAREAAAHLKDKQAGEAWVAGAIGPLGVRLEP
LGKTGLAEAREAFEEQMQALVTAGVDLLIIETMPALNEAREALSAAKTIAPDIPVAVMIT
VDEEGRCLDGASPEQAAALLTEWGADALGCNCSTGPSTVLTAIEAMRTATHLPLMAMPNA
GMPRAVEGRNIYLCSPEYMASFARKAIKAGAQFVGGCCGTTPNHIRAMKSALRALDAQSH
ITLNEPARVALSEETPPLPLAQRSFVGRLIAEGQFVTLVEIVPPRGIDCDKEIEGARLLA
SLGVHAINVPDSPRASARMSAQSLCIQIQQKTGIETVLHYTCRDRNILSIQSDLLGASSL
GLRNILCLTGDPPKLGNYPDATAVFDVDAIGLVNVVRRLNHGLDIGSNAIGGSTNFTIGV
AANPGVPDIEQELRRFAWKVDAGAEYAITQPVFDMRLLEAFLKRIEQFRIPVIAGIWPLT
SLRNAEFMRNDLRVSMPEAIMLRMAQAESPEAARTEGIRIAQEMLAEARPMVQGVQVSAP
FSRYSLAAEILTSVLSKTANLSVQNS
>A0A7X7VW17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistaceae bacterium|TrEMBL
PPRFTRIIARYANSPAALAEAGVAYATDQIVDLLAAGVDGIHLYTMNRPETTRRIMGNIG
QIRKTASPEGREKG
>A0A7Z1NG56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. cynarae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDT
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLIGR
>A0A8F6UDF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus sp. J1M15|TrEMBL
MSHPPTRPGTVAELLSSATGPTFSFEFFPPRSEEEEPVLWRAVEALAPLEPSFVSVTYGA
NGSRRDRTIHATRRIASAPGGPLTVGHLTCVDQSKADIADALAAYREVGVRNILAIRGDM
PGGGEWTRHPDGLANATELVRFIREQGDFCVGVAAFPNPHETSNDADLDARILAEKVDSG
AEFAITQLFFDAGRYSELVARMRGLGCGVPIIPGVMPLTVITQIERFADLSGRPLPEDFV
ARLRAAPSKEEVRRVGLAAAVDFCRDLLDAGAPGLQFFTQNRSKATREVLAELKAAVPAV
AEAGR
>A0A1W1H5D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfamplus magnetovallimortis|TrEMBL
MKSGSRLERVLKAGHFAFTGEVGPPRGANVEHLREKISHLKGMVDMANITDNQTAMVRMS
SWAASLICLQEGLEPNYQMVCRDRNRLAMQADILGAYTHGIRNMLCLSGDHQMFGDHPQS
KGVFDLDSMQLIMMVKKMRDEGKFLGGADIDVKPELFIGAAANPFAEPFEWRVHRLAKKV
AAGADFVQTQCIYNMPKMREWVRQANEMGLTEKVYILAGVTPMKSIGMAKYMQNKVPGMD
VPDDIIKRLQGVDKKKVADEGIKIACEQIEEFKEMKGVAGVHLMAIEWEHKVPEIAERAK
VLPRPEV
>A0A5C4QI00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora orduensis|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTEAGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATDTTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPEGVDYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCATPILAGVMPVTQIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRQLGIEQASEMSRRLLDEGVPGIHFITLNRSTATREVWQNLK
VGARV
>A0A2G4YVF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paremcibacter congregatus|TrEMBL
MLKPSLFAAEAKDIDVSFEFFPPKTEKMEQALWSSIRKLEPLHPGMVSVTYGAGGSTRER
THATVSRILKETDLLPAAHLTCVAATKGEIDDIAREYWDMGVRHIVALRGDMPTIGQAYA
PHEQGYKNAADLVTGLKKIGDFHLSVAAYPESHPDSANPAADIDNLKRKIDNGADQAITQ
YFFDVDMYFRFMDRVLAAGITVPIIPGIMPVTNFAQAKNFSGRCGTSIPAWLATLFEGLD
DRPEIRRHVAATVAAEQCMRLYQGGVKKFHFYTLNRSELTTTICHFLGIRPEGEIS
>A0A2A9JCC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)|TrEMBL
MSETTRTLQRHLENARFEVLPLRGVVEQVGNLPEGTTVTVTSSPKKGVEATLDVAARVRG
LGHHVVPHLAARLLTGPAHLAAVLDRIEGLGMTEVFAVAGDSAEPAGPYPDALSLLRAME
ELGRRPSRVGITGYPERHAFIPDATTISAMSEKAAHADYIVSQICYDPHALASWVKDVRA
RGVVLPIHIGVPGVVDVHRLLRISLKIGLGESMRFLRKQHGVVTKLLTRYTPEELFDELS
PHLADPAYGIAGWHFFTFNEVDRTDRWRQDLLARIGEVPA
>A0A388NZS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clavibacter sp|TrEMBL
MNSAPTFSVEFFPPKDQAGEERLWSALKALAVYKPDFVSVTYGAGGSTRDRTVRITSEIT
ARSGISTIAHLTCVGSSKDELIEILNQYKASGIKSILALRGDPKGGPGVKWESTAGGFDH
ADQLVTLASSMGFEVGVAAFPDGHPASMGNFEQDIKVLLEKERCGASFATTQFFFDVKGY
INLVDEIRAKGSKLDIYPGILPITNFAQLKKMSELAGSPIPSEVQRRVEAAGDTPADVVK
VGVDIASELSKKLLDYGVPGLHFYTMNSAAPTIEIIKRIGLR
>A0A1G3JU39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium RIFCSPHIGHO2_01_FULL_65_20|TrEMBL
MTLSLKQLAEAREALGAPLFAGLAGDVEVSFEFFPPKTEKMEATLWDTLTTLAPLGPKFV
SVTYGAGGSTRERTHATVARIASETAIPAAAHLTCVDASRDEIDSIAQSYWDAGVRHIVA
LRGDPPRMGEKFVAHPRGYANAAELVKGLKQVAPFEISVAAYPETHPDADCADSDIDNLK
RKLDAGADQAITQFFFSPEAFFRFRDAYTRAGITAPILPGILPVSNVATTRKIAGACGTE
IPQWMNDLFEGLDDHPTTRQLVAATVAAEMCRRLYSGGVRHFHFYTLNRAELSFAICHLL
GLRAPKVAAAPVLQENAA
>A0A710B1H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTTARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A5M6L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae SP14-BS69|TrEMBL
MSCQTPSLSFEVFPPNPAVGNDNIILALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A832TLH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRFSDTLEDARQIKGIVDAINVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDYPTCGDHPGSKP
VYDLDSVQLLQLVRKLDSGIDFAGNKLDGGTSFCAGAVSGIDPEKPLQLIKLEKKVRCGA
DFIQTQAVYDIGMFEEFTEAVNYLEVPIIAGLIPLKSMGMAEFMNKNISGIHVPEEIILR
MKDASSPMEEGLLIASETIKELTKLSRGVHIMPIGSQRYTPKLISMAGISEK
>A0A809RTL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosymbiomonas proteolyticus|TrEMBL
MKLSDALAQPVVCGDGAYGTLLAARGFPKQPYDLANLEAPELVADLHRLYFEAGAVLIET
NTFTANRFRFVDLRDDLYEINRAGARIAKAACGDGAVILGAIGPAGKPMYPLGSISSSEV
IESAREQARALEEGGVDAFLLESFLDLDELERVVEGVRQASNLPIIASKAFIEDGEAISG
GLPYQCAKRMAAMDVAAVGANCVVGPQRMLDLVRMMTEATSKPVLAYPTPGMPTLIKGRV
AYDTDPTYFAKACRRLAEEGATLIGGCCGTTPDHIRALSQELGRSPVQRAKRASVATRDY
ETKPLESTPRTEFGERIARGESTYSVELDVPRGLKLDRLMADVEAVRAAGAHTINISDGA
RARLRMNPTAVCHLIQSTTGAETTMHFSCRDRNLLAIQADLLGCHALGVRNVLAITGDPA
NIGDYPSATSVFDVDAVGLVRILGRLNEGIDLAGYGIGRKCGFTICVAFNPGSPRPEVEL
VRLQQKADAGAHAVYTQPVFDESLVEIALESCKKVGLPCLIGVMPLRNARHAEFMHNEVP
GILVPERLRAALADAPDDEAALDLGIGQALRLARLAKSGGAGVYLMPPANRITAAVKVLE
GIR
>H8XQJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium indicum (strain DSM 17447 / CIP 109464 / GPTSA100-9)|TrEMBL
MKVTQHIENAKGKTLFSFEILPPLKGQNIQSIFDGIDPLMEFNPPFIDVTYHREEYEFKE
LANGLLQKKIVKKRPGTVGICAGIQNRYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKTETYFKPEKEGNEYASDLVKQISNLNEGVYLDEDLQNTAQTNFCIGVAAY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNKKFFDFVAKVRAAGITVPIIPGLK
PIATKKQLNLIPHRFSLEMPDDLIMEVVKAKDNDAVRQIGIEWCIQQSKELVAAGIPVLH
YYSMGKSDNIKAIASEVF
>A0A2S6PWB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. QL37|TrEMBL
MALGTPSTRTDHARTVRELLATGETSFSFEFWAPKTEKGERNLWNALRRVEAVGPSFVSV
TYGAGGSTRAGTVRATQRIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVRYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDTDIGHFVD
KCRAGADYAITQMFFHPESYLQMRDRVVAAGCDTPVIPEVMPLTSVKQLERFAQLSNASL
PSSLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A448PZZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MTALNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLTNFVRKARAGADSAITQYFFNADCY
FYFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQA
FGEHAITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A482ZRF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured SUP05 cluster bacterium|TrEMBL
MKISFEFFPPRTEKGQETLKQVRQELSLVNPDYFSVTFGAGGTTQESTLKTVLDIQKDGR
ISAAPHLSCIGSEKNKIIELLDQYQAAGIDRIIALRGDIPSGVRDIGDFHYANELVEFIK
TEYGSHFHIEVAAYPEKHPQAKNIQTDLTHFANKIKAGADAAITQYFYNADAYFRFKDEV
EKLGINIPITPGIMPITNYTQLARFSDMCGAEIPKWILERLKYYENDLESLSKFGTEVVS
NLCQTLKSQGVDSFHFYSMNHSQPSLKIAETLI
>A0A2G5R1H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. X|TrEMBL
MTLPPTRRVIGPVARAGERTERPRVSFEFFPPKTPQMEESLWQAITRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRAEVDEVIRDYWDIGVRHIVSLRGD
PPPGEGGIGGVYVPREDGYANATELTKAIRGVAPFEVLVGVYPEKHPESPSLEHDIDVLK
QKVDAGATLGISQFFFDLDAFLRYVDKVRAAGITIPIVPGIMPVTNFSGLKKMAAACQTT
IPGWLANLFDGLEDDAETRRLIACSVATEMCAKLQEQGFEDFHFYTLNRADLVYAICRVL
GLRETSPAPAEAAA
>A0A1F9PZI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrionales bacterium GWA2_65_9|TrEMBL
MRIAELIPTRRPFLSLEFFPPKDRDTWPKFFEEVEKLKVLDPLFVSVTYGAGGGTQANTL
DIVTHLKNHLGLEPMAHLTCVGASSQALHGFLKAITEAGIQNVLALRGDPPRNVEGFSFE
GQEFRHASDLVEFIRRHYPDMGIGVAGIPTMHPESASLADDLKWLKHKVDAGGQFVVTQL
FFENELYLGYVQRLRELGVSVPILPGIMPILSMKSAEFIAGLNGRAVFGGFYETLEAAFA
KGGDAAVRELGLAHATAQVQGLLDAGVPGVHLYTLNRAEACLSIMNNIIIR
>A0A244EM68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDGKEDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VQFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITRMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>R6JWL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:248|TrEMBL
MKVTEILKQDKPTISFEVFPPKKDTDFADVEAAATSIAELNPSYMSVTYGAGGSTKGLTI
KLAEGIQSKYNVSTIAHLTCVCADKTGISQALEDMKAAGIKNILALRGDIPKDYAGEIFT
EFAHASELVKLIKASGDFCVGGACYPEVHPDSTDKKADIDGLRKKVEAGCEYLTTQMFFD
NDIFYNFMYRIREAGIMVPVVPGIMPITKRAQVKNAVRLSGCNVPERFKNIVDRFGDTEA
AMRQAGVLYATDQIIDLIANGVNHIHIYSMNKPEIARAIYDNLSHIII
>A0A2H5WFI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR12|TrEMBL
MTSRLERLVRAGTFVVTAEVVPPRGADGAVVRAQARELVGYADAANVTDNPRASVHMSPV
AGAAFVAAAGLEPTMQITCRDRNRLGLAADLLGGWALGARNLFCLTGDPLGAGDEPDAIA
VHDLAVEDLVRLASELRMRGRLPSGAAIADPPAYFVGVADVPLAPAYDPARLERKLDAGA
GFVMTQIAYDLDALAGWLDLVRSRGITERAAVIVGVAPLRSAAQARFLNERVPGVLVPPA
LVAELEEAGDLAPQVGVARCVELVRRLREAPGVAGVHVMGMGHEEGVRAVIEGAGLLPRP
PAPEPSRADG
>A0A2G5KH61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter sp. 4U21|TrEMBL
MKVTDHIKKAAGETLFSFEIIPPVKGRNIQELYNNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMREEKYFEATKGGHPYATSLVKQIQDLNCGKYLHEVIETDDCADFCIGVAGYP
EKHLEAPSLKTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVAAAKNMGIDVPIVPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVEDCGTNKEVRQVGIEWAIQQSKELKEAGVPVLHY
YSMGKSDNIKAIAKTIF
>A0A831UY18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKPDFLEYLQNHVVLADGALGTYLYEKGVELGRNLDLLNLQAGELVFSAHEEYIRAGSQL
IETNTFGANYFKLREGGVEDQVREINRAGAQIAAKAAGHQIYVAGSVGPTGVKFPLDEGD
ATAEDIGEAFREQITGLVEGGVDLIIVETFSNLEEIILAIRAAKTVAPHLPLVAQMVFPA
RGMTVRGEDALACGRKMADAGADVVGTNCGRGIDAMVTAVKQMMPLAREGILLSAFPNAG
LPEMVGHRMIYPAQPSYMATRAGEMIKCGVHLIGGCCGTSPAHIQEFRSSLKIKPVRIRA
ENITEQPEKIPQKSVEDFPGGFLSSLTPGRVPIIVELDPPTHLDVEPVLAGADRLAGAGV
DAISLGENPLAILRAGNLGVATLIRRKTGLQTIIHQTGRDLNALGLQSRMMEAHLLGIEA
VLAVSGDSASATDQPGVSGVFDLRSYGLIRMLRNLNNGMNSAGRSIKHKTNFSVGAAFSF
RPESPRVQVQRLEKKADLGARFAMTQPLFTREAVEQMIDKTSHIDMLIFPGIFPVISSRN
AEFLHNEVPGISVPKELRERLASFEQVADQRKAALEYTMELVENIAPVVDGFYFVSPLNK
WEIALEFVNHVRRSGWKGSGRADRYCKPNH
>A0A7C0WVP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLERVLASGAFAVTGELGPPKNSDPDIVRQKARILKGNVDAVNITDCQTAIVRMS
SIGAGLIAQSEGVEPVIQMTCRDRNRIGMQSDLLAASAMGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQMLGMVRDMRDGKKFQCGEEIKGPEPRFLLGAAANPFAHPFEFRAVRLGKK
VANGADFIQTQIIYN
>A0A838N653|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilus sp|TrEMBL
NRYNIDAVPHIICGGFTKEETENALIDLNFLGINNVLVIRGDAIKTESTFSPEPGGHSYA
TELLEQVVNMNNGIYIDEDLRDVAPTNFCIGVAGYPEKHFEAPNYKSDLKYLKQKIDSGA
DYVVTQMFYDNKKFLAFVEDCKNLGINVPIIPGLKILTSKKQIATLPKIFHIEIPEELHD
EVEKCNSDQQVRQVGMEWAISQSKELIKAGAPCLHYYTMGNPETTLKVAKAVF
>A0A7C1G3V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
AGIAVKAAGHQVYVAGPVGPTGLTFPLDEDEVREEDIRQAFNEQIAALVEGGVDLIMLET
FPCLDEILPAIAAARAVAPHLPLVAQMVFPARGMTVRGEDALTCGRAMAAAGADVVGTNC
GRGIDAMATAVRRLAPLAKEGVILSAFPNAGMPEMVGHRMIYPAQPAYMAMRSGEMIRYG
VHLLGGCCGTGPEHIHEFRSTLKIRPVRIPGGRLVVAPDKTPETAVAVRTGGFLAGLQTN
RLPIIVELDPPTHLDVAPVLAGARALTEAGVDAISLGDNPLATLRVGNLGVASLMRKETG
IQTIIHQSGRDLNALALQARMMEAHLLGIEAVLAVSGDSASATDQPEVSGVFDLRSYGLL
RMLRQLNGGLNMAGRSIKHKTNFSVGAAFSFRPDNPQLQISRLEKKFELGARFAMTQPLF
SREAVERMMDKTSHLDMLIFPGIFPIISARNAEFLHNEVPGMSVPAEFRRQLASYPGVPD
QRKAALDYTRQLVEDIAPIVDGFYFVSPLNKWDIALEFVRQVRQAGWQGSGRATP
>A0A5K1MPF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii NIPH 615|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANYMVKHKVAGIVITPHMLKVLADEKRAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVK
TGEEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
VLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A8I0XN73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. NZS11_1|TrEMBL
MALSLKEKIVDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQDRPFAFKQTVDPREYSHLLRNLSAQDVITYKSVAQRGVGEFKDWLSETKNDYNL
QNVVLVGSPSSIGDIKLSLPDAYKAMAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGITPQRIILTFTPCGGEKTLDFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKLIA
>A0A831P2G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MVSNFKKALESGKFVVTCEIAPPKGTNLEKMRHHIELLKDKVDATNITDHQSSVMRFPSL
GGALLVKECGGEPILQMTCRDRNRLALQADLLFAYSRGINNVLCLTGDSVIFGDHKEAKG
VFDLDSSQLIMAIRKMEKGKDLGGNDLDGELEFCAGAIVTPEANPLEPQLIKFEKKIDAG
AEFIQTQAVYDLDNFKKFMDYAREFPVKILAGIILLTSAPMARFMNKNVAGVNVPQNLID
EMASAPKGKAIEKGIEIAGRMIRRIRQERMCDGVHIMAIGREELVPDIMSAAGLL
>A0A6H3NW31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira bandrabouensis|TrEMBL
MHISQVLGKKQTTISFEFFPPKNQEASEDLFRNIQKLSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEETGLTIVSHLTCVGSTKEEIREILKRYEKSGIHNIMALRGDPPKGQTEFQKT
ENGFAFAGELVGFIKKEFPQMGIGVAGFPEGHPSTPNRLKEIEYLKWKVDQGADYICTQM
FFNNNYFYDFVERCEIAGIKVPIIAGIMPVTSRKGMARMAELSLGTNFPAKLLNSLSRAE
DDVYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRKIYESLGIRNFDSIH
>A0A7X1GZZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKTESVLEKVLASGELAVTGECGPPRGALPDVVKEKAALLKGYVDAVNVTDNQTAMVRMS
SFAASVFLRQMDLHPVFQMVTRDRNRLAMQGDIIGAYSHGINTMLCLSGDHPKFGDHAMA
ANVHDLDSMQLIQTVRGMRDKGLFQGGAEIKNPPKMFIGAAANPFADPFELRVARLAKKV
KAGVDFVQTQCIYNIDKFETWMQGIRDRGLHEQVYIMAGITPMKSAGMARYMKNKVPGMD
VPDELVKRMAGVPKDKQAQEGIDICIESIERLRQIEGVSGFHIMAIEWEEKVPEIVKRAG
LYPRPQV
>A0A8J7AMW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Romeria aff. gracilis LEGE 07310|TrEMBL
MSPRPGQPAAEGQFRSAVKAGEFLITAEVMPPKGGDPSHMLAMAADLKDWVHAVNVTDGS
RAVLRMSSLACSALLHQAGIEPICQVACRDRNQIAIQADLMGAYALGIRNVLALTGDPTK
AGDHPKAKSVYDLESIRLLRVIQQLNRGVDLNQKALPDQPLDLFPGAAIDPQSPSWSGLQ
RRFERKLTSGAQFFQSQLISDFNRLEKFMDQIAAGCDRPVLAGIFLLKSAKNAAFINRCV
PGVQIPQSIIDRLAAAPEPLQEGMTIAAEQVKMAQQICQGVHMMAVRREDLIPKILEMAG
VSPR
>A0A7Y5IBE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudanabaena biceps|TrEMBL
MTAALNLAEARALLLSPLGPVARAGSNPTPPRVSFEFFPPKSDAAEENLWQAIRRLAPLN
PAFVSVTYGAGGSTRARTHRTVSRILAETALKPAAHLTCVEASRDEVDEVIREYKASGVR
HIVALRGDPPGTGGIGGVYQPRPDGYANATELARAIAAVGGFDITVGVYPEKHPESPSLD
HDIDVLKAKVDAGATRAISQFFFDIDAFLRFRDRVRAAGVTLPIIPGIMPVTNFAGLKRM
SAACGASVPSWLAGHFEGLDDDPDTRRLIAASVAAETCARLQEEGFADFHFYTLNRADLV
YAICRVLGVREVAA
>A0A848YV25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKLKEALGKKKFVVTSEIQAPMGDEQPEKMIDNLKRIRGRVDSVTVTEMELEGVVGDSIK
TCRMLQENRFDPIYQTTTRDKNRIQLQKDLSTAHEAGVDNLLVFTEDYRITGDSLQETMF
FHVDSGKLASVLEHIRKGRTVDGQDLPAPVDFTLGSGVESLWGQNVPKKGMEEMEFMCNI
GTGYFLTTPIFDLDQFRKFLGQVNTFGVPVIAEVMILRNAGMARFLNRHFKTGLVPDWVV
QKLSDTPDKLKASIELFSDTIKGLKELCQGVHIITLGGDDKLQPYLDAAKLR
>A0A351A3L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera sp|TrEMBL
MNTELSIEFFPPQTAEGAHKLRATCAQLAALEPAFFSVTYGAGGSTRERTFSAVKEIAAA
GHEAAPHLSCIGSTRDSIRDILQEYADAGIRRIVALRGDLPSGAGAAGEFRYANELVEFI
RAETGDRFSIEVAAYPEWHPQAKSPKDDLAAFKRKVDAGANSAITQFFYNPDAYLNFVEA
ARKMGITIPIVPGIMPIVSFSKLARFADACGAEIPRWMRKSFESYGDDSESIRALGLDVV
TRLCERLIAEGVPGLHFYSMNMAGPTIEICTRLGRSLRQD
>A0A0J1M1G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. MGH105|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A525CSK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MNLKNKLTNGEFSVIAEMSTPKGVDISDLVTSARNLKSRVDAVVIPDMDNGVMHMSAIAG
AALVRQQGIEPMIHVYGRDRNRMALQGDMLAAHVLGIPNLLVVQGEEMSLGDHQDAKLVD
DLNERDILVMVDTLKKGSDLAGFELKGSPDFFAGCQVNPMTDDKDLDAEFNRAKEKVDAG
AQFIIVPPVFDINSYTPILEKFKSLDVPVIATVFLLKNVGMARYISINDPGSRLTDALIT
RIRTAKDRETECIAVAGEMIQALGKVVHGVKISAMGWEDRLPAILDSAGI
>A0A3C1SAI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
KCYILAGVTPMKNVGMANYMKNKVPGMDVPDEIIKRLKGVPKDQASEEGIKIALEQIEEF
KTMKGVAGVHLMAIEWEHKVPEIAERAKVLPRPVV
>A0A2A3ZJS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MEATTATKVLDDFSLEMTGKDVPSLQQAAHAIPQGTRVNVTFLGNENQQMRVEAVKEVLE
LGFVPVPHISARRLKSETELREFLEALQQAGASEHVFVVGGDPATPEGPYFDSLSVIRTG
ILPEYGVTEVGIAGYPEGHPGISTTNLWEHMETKSASLAEQGLGQVVLTQFAFDAEAVVA
WVHEVRSRGIESDLRIGTPGPAGIKRLLGYARRFGVGTSAGIAKKYGFSLTNLIGTAGPE
RFLKDLTSYESIISASSGVKTHFYTFGGLEATAEWVQDFTAQA
>A0A525DBD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSSFLTGIQNEFIITIEVVPPEGGNPGPLLNELKAISTLPFHGFSIASNPIAKPRMSAMV
FSYLLQNHTRKPAVLHCCIRDQNRTGMQALLWGARALKIDSILAMTGDRAKAGDVILNDP
MDVFGLIRLSRDSGFHTGAVLDFRPEINGLKAEVRRLEQKKTAGADYIVTQPVYDTETAM
AIHQAVKHLEIPVIMGILPLISIRHARFLHEKVAGISIPDYLIGRMEKAKSPLNEGIEQA
KALLNISREWFSGACVMPPFNKFHILSKILEAP
>A0A0L0M0N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Paraburkholderia kirkii|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRATRAQLATLSPKFVSVTFGAGGSTQQGTLDTVLEMAA
ERLEAAPHLSCIGSSRDNLRAILSQYREHGIRHIVALRGDLPSGMGAIGELRYASELVAF
IRQEHGDWFNIEVAAYPEFHPQSKSPRADLENFVRKVKAGANSVITQYFFNADAYFEFVE
EARKLGVDVPIVPGIMPITNFSQLTRFSDMCGAEVPKWIARRLESFGDDRESIRAFGVDV
VTGLCRRLIDEGAPGLHFYTLNGAWVTKTICERLGFKNA
>A0A0G3EU26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea thiooxydans|TrEMBL
MTQRSFSFEFFPPKTAEGSDKLRATRMQLAPLKPRFVSVTFGAGGSTQQGTLDTVVEIQR
EGTEAAPHLSCVGSSREGIRAILDTYRNHGIRHIVALRGDMPSGMGEIGEFRFASELVEF
IRAETGDWFHIEVAGYPEYHPQARSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DTRKLGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWIAKRLESFGDDRDAIRAFGLDV
VTALCERLLAADAPGLHFYTLNGAAATKAIWQRLGLS
>A0A8G1ZJL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium cupriresistens|TrEMBL
MTLNDPAAPLYADLAGDARVSFEFFPPKTEKMEAQLWSAIETLAPLAPKFVSVTYGAGGS
TRERTHNTVARIASETPLAAAAHLTCVAASKDEIGEIADAYWDAGVRHIVALRGDPPEVG
GTFEPHPDGYKSAAELVDGLMKRHSFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFSPEAYFRFLDKTAAAGITADIVPGIMPVSNFAATQRMAAMCNTQVPNWMARLF
EGLDDHPASRQLVSATIAAELCRSLYAGGVRDFHFYTLNRAELSFAICHLLGLRAKAAVD
A
>A0A7W1RM87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MHITDIMRKDSPTFSFEFFPPQTPEAAETLYQTIRELESYMPDFVSVTYGAGGSTRALTH
DLVERIKTTTKLNPIPHLTCVCHREDEIEAILLRYAQSAISNILALGGDPPRGLPYDKAR
DSFQHAVDLVKFIRRFNESGAHPDPRGFGIGVAGFPEGHPATPNRLVEMEHLKAKVDAGA
DYIVTQLFFDNRDFLDYRERCALAGIHLPIIAGIMPITSMSGFKRIAELAGGARFPARLL
RALQRCEGDRKMVSRVGVHFALEQCHDLLDNDVAGIHFYTLNRSDATRVIFDSLGIPRLR
GASAAL
>K0XI58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoanaerobaculum sp. OBRC5-5|TrEMBL
MENIRDYLKNNILLFDGAMGTYYDELTDDGIGCELANIKNSELIKGIHNEYIEAGAKAIL
TNTFSTGIDAFSGDRELQKKVIVAGIDIALEVAKSRAYVFADMASINADSNSAAFEEYKI
IADIFLEKGINNFYFETRNSTIGLKSIGEYIKEKSPEAFIIASFAVMPDGYSSEGYYYKT
MFKEICESGFFDGVGLNCVSGANHMAKLLKDVDTEGLYLAAMPNAGYPIVRDNKIHYGSL
ANYFAAQIEDILDMGVNVVGGCCGTTPKHIELLKKSMSGMLIKPRKSVKKEKNISQKIRL
NRFEQKLISGQKPIAVELDSPIDTNIAKFIDNAAKLKSAGADIVTIADNPIARARMDSCL
LACKVRNELDFDVLPHMTCRDRNVNAAKGLLLGASAMGVDNVLVITGDPIPNAQRDEIRS
VFEFNSVKFANFIKSLNDEVFESPMNICGALNVNAKNFSAELRKAKRKQENGVKVLFTQP
VLTKRAIDNLKEARENLDVKIMGGIIPIVSERNARYMQSEVNGIYITDDIVEKYIGKERE
EAEEIALSMSKEIANEIYDLVDGYYLITVLNRVNLMERLIKTVKEVCENR
>A0A371I4R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucuna pruriens|TrEMBL
MKITEKVLAADSNRVTEDGVHNLFERMERMVAQNPSFCNITWGAGGTTADLKLEIANKMQ
NIVKHIRAKYGDYFGIQSDFMDADVLAEAHLDVVESDGLSTLESYQNDLA
>A0A5K7YUE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina widdelii|TrEMBL
MTLELVPGRESTGRSVDTVMGIAKDAFADGRVSAVSITDNPGGNPSLSPDAIGYRIFSIG
MDVIVHFTCRDMNRVGMESRALQLAMMGMKNILALTGDYSGKGFGGQGAPVFDIDSVNLH
IMLNLIGKRINAAGDPDSFFSGGAVSPFKRTEGECVAQYAKMSRKVAAGAQFLITQLGYD
ARKFQELIGIQRHMGIDVPTLGSVYVLSPHAARIMNQGRVPGAVVTDDLLHSVEKEWKDK
QEGRKFAIERAARLGAVLKGLGYRGIHIGGIHRDFATVGKILDRMEQIGDDWQQWLPRFN
YPQSNGFYAFRETPPETASKTTLGLAPRPLPVVDRILYPLMKVSHNLFFDFDSFLAPLYK
AICSALDGNIAGSLFLRLIEHPIKRMLLGCRQCGDCAIQHVGFLCPEWGCPKHTRNGACG
GSRDGMCEVHPDRPCVWFRAHNRLAAKGEIKQMCEGCVPPRMWELDETSSWINFHLGRDH
QSSGNEIAGFCRKATCRLLVEE
>A0A100JIE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces scabiei|TrEMBL
MAAAGLRALLRTVRYEVLPTGATEEKVLAHVPRDVVVTVTASPVKGLEPTLDLTGRLAAH
GYRVVPHVPARLLRDDRHLKEVVDRLREAGVDDVFVPAGDADPPAGPYDGALPVLRRLSE
LGGPFARVGVTGYPESHPLIHDDVTVQAMWDKREHATYVVSNLCFDPRVLGEWLARVRRR
DVTLPVHVGVAGPVQRAKLLSMATKIGVGESTRFLTRHASWFVRFAAPGGYAPEKLLNRT
EKALTDPASGVAGLHLFTFNQIAETERWRRSLLDRLEG
>F9EP12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. animalis ATCC 51191|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSLEKPDYISVTYGAGGNTKGRTV
EIADRIKRQNGLESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEKGD
FNYARELIEYIHKKKGDKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRHE
>A0A1G0NIY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium RIFOXYD1_FULL_62_11|TrEMBL
MSQRTFSFEFFPPKTAEGAEKLRATRAQLAQLKPKFFSVTFGAGGSTRDRTLETVRDIQA
SGSEAAPHLSCIGSTQDNIREILNEYKSQGIRHLVALRGDLPSGSMDAGEFNYANELVSF
IRKETGDWFEIEVAAYPEIHPQARSWTDDLANFKRKVDAGANSAITQYFFNADAYFRFVD
EARALGVSIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLASIRAFGLDV
ITDQCERLLAGGAPGLHFYTMNQAGPSTTIWQRLGL
>S0FAQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola coprophilus DSM 18228 = JCM 13818|TrEMBL
MRVIDLITSSEKTAFSFELLPPLKGTGIERLYGDIDKLKEFDPKYINITTHRSEYVYQEL
GDGLYKRQRLRRRPGTVAVAAAIQQRYGITVVPHMLCSGFTREDTEYVLLDLQFLGITDV
LVLRGDKARHESAFVPEPGGNAHAIELEEQINDFNRGIFVDGSPIRAPHTPFSYGVACYP
EKHEESPNAEQDLLWLKRKVETGADYAVTQLFYDNNRYFSFVKRAREAGITVPIIPGIKP
FSKLSQLTMVPKTFKVDLPDELAREALKCKTDEEARALGTEWCIHQCRELMAGGVPSLHF
YTVGAVDVVRDVVKAIF
>A0A2U2J2M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingosinicella humi|TrEMBL
MSSLAPASGQRNRPLFADVAGDIAVSFEFFPPKTEKMEQTLWESVKTLEPLGPRFVSVTY
GAGGSTRERTHATVERIARETSLQAAAHLTCVEASRAEIDEVARSYWAAGIRHVVALRGD
PPEPGTPFKPHPDGYANAVALVKGLKAIAPFEISVAAYPECHPESRNKAADLDNLWRKID
AGADRAITQFFFSPECFFRFRDQAAAMGIDAEIVPGILPVSNVAQTRKFAGQCGATIPTW
MDRLFEGLDNLPAARQLVAATVAAELCGQLYAGGVRHFHFYTLNRAELSYAICHLLGLRP
RADRQEQAA
>A0A1T5AL68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea thiooxidans|TrEMBL
MNAFRPSRHGSRRPRVSFEFFPPKTAEMEVALWESVRRLEPLGPSFVSVTYGAGGSTRER
THATVKRMVDETALKPAAHLTCVSASKAEVDDVIRSYWDAGVRHVVALRGDPAGGLGTVY
EAHPEGYQQTCDLVAGLKRIGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRARGIEIPILPGIVPVQNFKQTAGFARKTGASVPEWLADRFEGL
EDDAATRRLVAAAVCAEQVLDLIDRGATDLHFYTMNKADLVYAICHLVGLKPEKQAAQAV
AAE
>A0A4R7LI22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoreibacter halocynthiae|TrEMBL
MTRPNVSFEFFPPKSVEASFRLWDTIQTLAPLDPTFVSVTYGAGGTTRELTHEAVTALHK
TTDLRVAAHLTCVDATREETLAIARDYIKSGVTDIVALRGDAPKGQDFTATKDGFASSIE
LIEALKTETDATIRVGAYPDSHPEAGSMEANIAYLKRKFDAGADAAITQFFFEADTFFRF
RDACVKAGIDKPILPGIFPIEDWTRASNFAKRCGTHVPAWLEEAFATAIRDDRHDLLAQS
VVTELCSDLVDGGVNDLHFYTLNRPELTRDICAALGVTQKLALAQVA
>R2SZV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus haemoperoxidus ATCC BAA-382|TrEMBL
MRTDTLFKDKTVFSYEIFPPRRTAPIDTIYHTLDRLKGQQPDFISVTLGAGGTGANLSTA
DIAQKIQDEQFLPSVAHLPAVNFSKGEIIAILEELKQKKVENILALRGDILPDKEPKKDF
SYANDLVAFIQEQGDFNIIGACYPETHSDAASSVEDIRNLKRKVDSGTNQLISQLFFDNH
YFYTFKEKCDIAAIEVPIQAGIMPVVNKKQIERMVKMSNVTLPTKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVTQGADGIHLYTMNNPYVAQKIREATRSLFEA
>A0A1X1B3K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia sp. 1135|TrEMBL
MTGPRLFVEYPARPDPDCPKRMVFGPCGGIRDDRSCEIDARPCPFGHNTQPVQWQGGQPG
RNSAGELLRAAEAGPVILTDLSVAAFDRGNLEEVAKIVGASSDSVLVGEHQNRPDFPPTV
MAQMIAGVGGRPWITLTCRDRNRVVLEQELMGLRQAGADGVFCVTGDGRAQGVRPDVTQV
FDLDGTRLTALAAQAGLSVGVPEAPQAEPTAIRPGRLLQKQRAGAGLAVLNHVGTVAALR
EFVSTARAAGVTIPIIAGVAVYTDERSARVLAAFPGLHLDPTEIARVVTSDDPRSMGIET
AVQEAADLLSVPGVAGVNLSGLASGSGEIPAAHVKAEVAERIRERMSAR
>A0A1F1EUD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC073B08|TrEMBL
MTTVHPALSFELFPPRSQASCESLLRTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSNTE
LHRIGVDYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEY
A
>A0A5A5RE31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa NIES-2519|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFDCLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>D3T3Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter italicus (strain DSM 9252 / Ab9)|TrEMBL
MLKNENLCNKLKKRKFVVTAEISTPKGVDVTKTIEKARKLKGIVDALNITDSPMANMRMS
PIAVAHLLQDHLNIEAIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDDPSHGDTPQ
AKGVYDVDSIGLLKIISAFNKGYDYNGNKLDSPTEFCAGTTANPNDLRDEAIEKLKVKIE
AGAEFIQTQPVYDEEILFKFIEKIKDLNVPLLVGILPLKSFKMAVNLNEKVPGIDIPEKV
LERLKDGGKEEGINIAVEFIKNVRSEVAGIHIMPLGNTDVVLEIISRIDDLACEVIQNKV
QMN
>A0A7T4R079|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spongiibacter nanhainus|TrEMBL
MDKRFSFEFFPPKTDVGRDKLINTRDQLAALEPEFFSVTYGAGGSTRDNTRNIVMDTKKA
GLSVAPHLSFGSDNEAAMLSLIEDYRDAGIDRIVALRGDMPSGMGATRLVYARELVEFIR
KHTGDHFHLEVAAYPEIHPDAPSYDQDITYLKEKLDAGANSAITQYFYSADAYFYFLDAC
EKAGIDKPIYPGIMPITNYDNLARFSRNCGAEIPRWLAHKLEGYGKDMDSVVAFGKEMVT
ELCHILLEGGAPGIHFYTMNQVEPVAGILKALKSD
>A0A2E4DP98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MKTWQKPSFRSLLQETSTFVTCVELVNSRGIITEREGTRVLKLARELSQHPQIHALCMTD
NAGGNAMLSADTMGTDLISRGQEVVIHLSCKDWNRNGLQSQAWKLASEGFDNILALSGDC
PVSGYKGQASAVFDIDSVGLLKMISEMNAGLEINVGQNKKKRVLKRTRFFSGAVINNHKR
YEREVMPQYFKLRKKIENGASFIVNQIGYDARKQDELLKYMNWSGLHVPVLYNVYVLSLT
AARFFHANNIPGVTVTDDLLALVVKQADSADKGKAFFLEFAAKQCAIAKGLGFRGVYLGG
HLKASDYKQVLEITDQFGDDDWQDFAQEICFSQTDEFYFFEPDIATKLSSTEVNREYLHS
KHLKASPVSRQNVPLSYKINRTIHDIAFKKGTVGFGLGEKISRAIERKNKGAQKIFHGLE
QTFKIAAFDCQDCGDCSLPDIAFLCPESQCAKNQRNGPCGGTKQGKCEVGEKECIWSLAY
DRLKAYGQEEQMLDGPVVFRNGALKGTSAWINTFLGRDHHGKNKK
>W2VG00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoanaerobaculum sp. MSX33|TrEMBL
MENIRDYLKNNVLLFDGAMGTYYDELTDDGIGCELANIKNPELIKGIHNEYIEAGAKAIL
TNTFSTGIDAFSGDRELQRKVIVAGIDIALEVAKSRAYVFADMASINTDSNSAAFEEYKI
IADIFLEKGINNFYFETRNSTIGLKSIGEYIKEKSPGAFIIASFAVMPDGYSSEGYYYKT
MFKEICESGFFDGVGLNCVSGANHMAKLLKDVDTEGLYLAAMPNAGYPIVRDNKIYYGSL
ANYFAAQIEDILDMGVNVVGGCCGTTPKHIELLKKSMSGMLIKPRKSVKKEKNISQKIRL
NRFEQKLISGQKPIAVELDSPIDTNIAKFIDNAAKLKSAGADIVTIADNPIARARMDSCL
LACKVRNELDFDVLPHMTCRDRNVNAAKGLLLGASAMGVDNVLVITGDPIPNAQRDEIRS
VFEFNSVKFANFIKSLNDEVFESPMNICGALNVNARNFSAELRKAKRKQENGVKVLFTQP
VLTQRAIDNLKEARENLDVKIMGGIIPIVSERNARYMQSEVNGIYITDDIVEKYIGKERE
EAEEIALSMSKEIANEIYDLVDGYYLITVLNRVNLMERLIKTVKEVCENR
>A0A369R9A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecochloris sp. ZM|TrEMBL
MLVKEILSSTDNPIFSFEFFPPKKNDDWDRLFRTISELIPFNPSYVSVTYGAGGSTRTRT
HDLVTKIRKETGLTVVSHLTCICSTKDEISDILSTYENNGITNVLALRGDLPPGTTSYSE
ATKDFPHAIDLVRFIKTNFPSFGIGVAGFPEGHPQTPNRLDEITYLKEKVDAGADYIVTQ
LFFDNRDYFDFVDRCALEGITVPIIPGIMPVTTKKGLIRMSELALGARIPAELLKEVIEA
PDDQSVAEAGIRWATKQVRELIDHHIKGIHFYTLNHAEATRMIFNNIPEAKSKEQA
>S9RCF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger mucosus DSM 16094|TrEMBL
MTGQTPERDISVSFELFPPKTEAGIEKLGHTVDRLAEAGPAYFSVTYGAGGSTRERTRQV
VDAVASRSGLPVAQHLTCVGASRAEIDRQAQGLWDAGIRRIVALRGDLPEGETLAEDGYH
DGAELVEGLRRIGDFDISVAAYPEVHPEAASDQGDLDHLKRKIDAGANRAITQYAFDTDT
VLRFVDRARKAGISAPIVPGIMPVANFASLKRFSSGCGASIPTWMEEMFAGLDETPDLRS
MVATSVAVEQCRRFVAEGLTEFHIYTLNKPDVTLAICRALGLPATIRADRAA
>A0A376BUB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alysiella crassa|TrEMBL
MPHHSKKLSFEFFPTRTAEGRAKQVITRKQLSQFNYSFFSCTSGAGGSTRDGTMQTIKDI
LSEDIPAAPHLPCIGMTADEIKDLLLEYKEIGVKHIVALRGDIPSGLGYSMEGMRYANEL
VELIKTEHGDYFHIEIAAYPEYHPQSRSAEDDINHFVRKAKAGADSAITQYFYNADAYFR
FVDDVRGRGVELPIVPGIMPIASFAKLARFSDMCGAEIPRWLRLKLQSYADDTASIKALG
LDVVTEMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>A0A076LRB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edwardsiella anguillarum ET080813|TrEMBL
MSFFHASQHDALNQSLAELQGRIQVSFEFFPPRSQEMEQTLWRSIDRLSTLRPSFISVTY
GANSGERDRTHGVIKGIKERTGLEAAPHLTCVDVSREALRGIARDYWNSGIRHIVALRGD
LPAEGGRPEMYASDLVALLREEADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGASRA
ITQFFFDVESYLRFRDRCAAAGIDAEIVPGILPVSNFRQLQRFAALTNVRVPQWMLAMFD
GLDADAETRKLVGANIAMDMVKLLSREGVKDFHFYTLNRAELSYAICHTLGVRPQRDVA
>A0A5A5RXH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa NIES-2520|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADATHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHK
>A0A2E7AK71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibacillus sp|TrEMBL
MDQNNDIADFLGKRRPSISFEFFPPRSAKAAERLFTTIHELKKLNPSFVSVTYGAGGSTR
ERTHKLVLKILEETTIPAIPHLTCVNHSLAEIEEILTGXAGARVPGILALRGDLPKGDPX
YDRSRDAFHYGADLVSFIRNFNRDLRTPLEKFRVGVAGFPEGHPETQNRLKEMDYLKXKV
DAGADYICTQLFFNNHSFLDFRDRCRVAGIDIPIIAGIMPITSRPGMERMADLAAGVHFP
AKLQRALQATGXDPVAFETAGTDYATNQCQELLSEGVEGLHFYTLNKSNATKQIATAIGG
S
>A0A3A8SQW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus sp. AB038B|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTVEELAPLEPGFVSVTYGAGGSTRDRTV
DLVTHIKKQTGIEAMAHLTCVGHTRDELRDVLRRLDAAGIENVLLLRGDPPLGQTTFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVGALKGRS
>A0A0C7NIE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Defluviitoga tunisiensis|TrEMBL
MKIVDVISQKGKPILSFEIIPPNRGGSILDIYNVVDGLMNFSPSFINVTKHANEVEYLEN
GLEVNKIIVNKRPGTVGISAALKNRYNVDVVPHLICVGFNKYQLEDILIDLHYLGIENVF
VVRGDKNRYTFREFDEHKYACDLVEQIVNLNKGIYVYPTRYNYSTDFCIGVAGYPEKHFE
SPNLEKDLDNLKLKIELGAQFIITQMFFDVNYYINFLDKISERGINVPVIPGLKPIVSKK
SLYNIPKSFFVNIPKELVEAFDEAKTPKDEFNVGVKHTIKMIEELLSSGVPGVHIFTMGK
GDAVKEVLREFQNVF
>A0A1G4PT66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylobacter rudongensis|TrEMBL
MSSDVERRSRRAGGRPISVSFEFFPPKTPEMEATLWNSITRLAPLAPKFVSVTYGAGGST
RERTHTTVERIVKETRLAPAAHLTCVSATKGEVDEVVRGYWDAGVRHIVALRGDPPGGVG
QTYEPHGEGYRTTADLVAGIRRSANFEVSVSAYPEKHPESPSFDTDLDILAAKVDAGATR
AITQCFFDNDLYFAFLDKARARGIDVPIVPGILPVSNFKQAKNFSEKTGTYMPEWLAARF
EGLDNDPETRKLIAAAVAAEQVFDLVDRGVTEFHFYTLNRADLVYAICHLLGIRPPQETG
AGDGKGQAAA
>A0A2K8K364|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella osloensis|TrEMBL
MTTPFSFEFFPTKTDDGQTKLLTTFDELNALKPQYFSVTYGAGGSTRERTLGIVKALSEK
SDTPITPHLSCIGDDKAKIGELLDYYKSLGINRLVALRGDLPSGMVGLGELPFAVDLVKY
IREHSGDYFRIKVAAYPEMHPQAKSFDADIQNLLNKYHAGATEAITQFFYNADSYLYLRD
ALAKKGVTQDEFPIIAGIMPITNASNLIRFADGCGADIPRFIRKQLADYGDDKKAIRQFG
FEVMVNLCERLIAEGVPSMHFYSMNQVTPNKQLIEALGLV
>A0A3A6EJT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium AM40-2BH|TrEMBL
MKIIDRLLEDKIHISFEVFPPKTDAGYEKVRSATEQIAGLHPSYISVTYGAGGGTSKNTA
KIASYIRDELGVESLAHLTCASSTKAEVQTVIENLKALGIENILALRGDIPEGMVFPSED
RYHYAYELVEAIRRSGDFCIGAACYPEGHVENEHKEDDIKFLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAMLDRFGDHPK
AMEQAGIAYATDQIIDLLANGVKNIHIYSMNKPHIAAKIMENLSEVIQC
>A0A2N3WZJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia fluminea|TrEMBL
MVQSLRTHSGNGVPFSVEFNPPRDEAGEARLWRAVREFERMHPAFVSMTYGAGGSTRDRT
VRITGALAQETTLLPVAHLTAVGHSIAELRSLIGSYADSGICNVLVLRGDPPGDPLGEWA
KHPGGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLDHDTHHLAAKLRAGAEYSITQ
MFFDVEHYLRLRDRVIAMDPIEGAKPIIPELMPITSLRTVARAEELSGRPVPPEVVARLT
RAAGTGPEEDRAAVRAEGIQIATEMAQRLTEEGAPCLHFITLNFAKATSEVLTNLGYGVT
AAPLSA
>A0A841GTU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosipho japonicus|TrEMBL
MKISQIKDFFISIEVIPPLRGHSADNLYKAIDKIMPYNPAFISVTKHPPELEYYEIDGQI
LKLPKVKRPGTMGIVAALKMRYNVDVVPHLTCIGNSKFELEELLIDLDFLGIDNVFVIRG
DKKKNVIKKEWQYDHAYQLVQQISEMNNGKYLYQTAKKTNFCIGVAGYPEKHYESPNLKT
DIKYLKKKIEAGAQFVITQMFFDVEKYFNFVELLRNEGITVKVIPGLKPILSYKSALKIP
GTFYVDIPEELMEKLDSARTPKEEFWVGVKYTIKLIEKLKKNVPGIHFFTMSNTDAIVEI
LKHV
>A0A7X8SAA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. P28RR-XV|TrEMBL
MSHIDENPLGVHLPLDPLPGHYSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNGKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFRDYMKKVRDLGLTEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDAVIKRIEGAQDQKKEGKQLCIDIINEVQEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRSDVLVAERLHQISEGREENQQAMAEIAA
HHTPPQAH
>A0A068NQ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fimbriimonas ginsengisoli Gsoil 348|TrEMBL
MRFTEALKRDFLIGDGANGTCLAERGFHRQPYDLANLQAPDLVREVHLEYFDAGADFVET
NTFQANRIRLVDLTVDVRELNLAGARLAREAAGDRLVLGAIGPCGKPMEPIGHITEAEVG
EAVREQAQALADGGVDGFILETYTDICELKVAVEAVQQVSSLPIIVSKAYIEDGEMLAEG
LPVRCTKAMGELGVAAVGANCIVGPQRMLDLVRQIAESTELPIIAFPTPGLPQLVKGQIV
YDTSPEYFAKAASRLVEEGAKIVGGCCGTTPAHIRALRRVLESGRIKPKPRTTVAAVTKE
RAPLATTEPSELAQKLGRKFVVAVEMDVPRGLNLNRLLAGARSLKISGADVINISDGARA
RLRMNPAAVSQIIQSQVGIEVTMHFSCRDRNLLAIQSDLLGWHALGLRNILAVTGDPANI
GDYPSATSVFDIDSIGLCRILNRFNEGIDLAGYSVGVKCGFTIACAFNPRSLDPVLELDR
LKRKVDAGASVVYTQPVFDDESADIAAKACDELGVPCLVGLLPLRSGRHTEFMHNEVPGI
RIPEWLRQRMADAENDVDAVEIGLEEAQRLAVHIKSVAKGIYLMPPFGSHAIAERVMAAL
>A0A2A8TX68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKSHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKESAIEEGIRISQELIDTAMKYFNGVYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A151V2L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASSLLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0D0ZYP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum B2 450|TrEMBL
MHIKELFNQKNLVFSFEIFPPKATSSVKTIYETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIKNILALRGDIPKDKNIIGE
YNYAFELIRKIKENDNFGVAGACYPEGHIECESLEKDIKELKRKVDAGAEHLISQLFFDN
NIFYEFLNKAQQKNINVPIQAGIMPVVNKKQIERIIKISRATLPKKFMKILDRYEYDKEA
MKDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARRITESTKSIFNSINKDVAV
>A0A669EMY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oreochromis niloticus|TrEMBL
MVNQVQRGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQSKEKITGYLAKAKHLGLKNIMALRGDPVGEDWEEEEDGFNYAID
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNY
GIQQAVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELQNEESVFEVFTSYITAQPNHCGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVNGRNLTNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWGK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPELHKATEV
>A0A6G4R3R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. 602-2|TrEMBL
MTLPPTRRVIGPVARAGERPVGAARPRVSFEFFPPKTEKMEASLWEAITRLAPLDPAFVS
VTYGAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRAEVDEVIHDYWNIGVRHIVSL
RGDPPPGEGGIGGVYVPREDGYKNATELTAALRGIAPFEVLVGVYPEKHPESPSLDHDID
VLKAKVDAGATLGISQFFFDIDAFLRFVDKARAAGITIPIVPGIMPVTNFNGLKTMSAAC
QTSVPSWLANLFEGLDQDPETRRLIACSVAAEMCAKLQEQGFNDFHFYTLNRADLVYAIC
RVLGVRESAPAQEAAA
>A0A1Q7MLH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenarchaeota archaeon 13_1_40CM_3_52_17|TrEMBL
MRLSDRARHHNLVTVELIPDRVVASDLALLRGRVDAITIPALRNGHNDPSYPKSFSITPQ
RRSLASASIINRAGITAVPSLTCRDCNRSDLSAIANQIAQGLGNVLIVYGDPYPQPHPGT
YEFTKTNELIREISSLNHGNDPCIGAVTNQHADNRENEISRTISRVDAGADFIVTNVAFD
SESVLEHRDALLGAGLGVPLFIQVSIPLSLNNVLFVSQKFDIPVPAHIRKKLSDDPSGGS
LAVAAEAYEALRGEANGIHFSYLFRQRNPIPTYRHLLETIGIAGPPLAPLAASALKTYPV
A
>A0A2H0P893|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG11_big_fil_rev_8_21_14_0_20_49_13|TrEMBL
MQNFLDTLNEHVILADGAMGTLLYERGVYLNRCYDELNLVNPDMIRKVHADYLEAGAELI
ETNTFTANRMRLASYGLEGKVKEINAAGVKIAREIAKDRAFVAGAVGPLGVTLAPLGRHS
VDEAREVFKEQIEVLAETKVDAIIFETFMNLDELEIAVRTAQAVTDIPIIAQVSFKHYRD
QEFVGVTPTQAVKMLESLNVAVGGTNCSSGPQGVLDAIQEMRKVSKIKLSAMPNAGMPQV
VEGRLLYLATPEYMGEFARRLVLAGASIIGGCCGTTPDEIKEMSRFIKSVAPHRKRVFKM
LSVELRAEPKFASLPTKDKSSFAAKLGNKFAVSVELDPPMGLCPKEAIEHAKFLHKNGVD
AVNIADGPRAVARMSPIALGALVKRETGIEPIVHYCCRDRNLLGMQMDLLGAHALDLRNL
LIVTGDPPKMGTYPMATAVFDIDSIGLIHMVNGMNKGQDMSGRALNAPTSFLIGCGVNPG
AVNIDLEVERFAKKVEAGAEYVFSQPVYDAELLENFFKKTAHIKEIPFFVGILPLASLKN
AEFLHNEVPGMQIPAHIMDRIRSAKTRELQIKEGLSIAKESLKGAKKMQRVKGAYIFPPF
GKYSAVVELLKVV
>A0A2B5Y1W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus toyonensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTDRNAILGTIGGMKHIGAATTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVVLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPDIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A376AF84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciceribacter selenitireducens ATCC BAA-1503|TrEMBL
MAIKHDRNVPPAQRLRYSFEFFPPKSEDMADQLWKTVDELCLWDPDFVSVTYGAGGTTRE
PTLSTVRRLIAETPLRTASHLTCVGATKEEVHQVVEQFRAVGVNHFVALRGDPQDGMGTA
YQPHPGGYANAAELVAGLRELGDFEISVSAYPEKHPESPDEAADIDMLKRKVDNGACRAL
TQFFFDNDVFERYLERVRAAGISIPIVPGIMPIQNLNQLKRFASMCGATIPGFLDKRFAG
LDEQPQARAEVAAEVAAEQIADLSARGIADFHLYTMNRSALVNATLRNLGLEPKGRRSEG
TGAAA
>A0A4R0W422|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGVTVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A376AFZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciceribacter selenitireducens ATCC BAA-1503|TrEMBL
MSPDFNPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLSTPPHVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PLASAKTAKWIRSNVPGIHIPDSVIARLEGAQDQKKEGKQLCIDIINEVKEIEGISGMHV
MAYRQEEYVAEIVHESGVLKGRKPWRREANPADALVAERLEHIREEKVEDQQQMAGLAAH
LTPKNSH
>A0A0F7KW10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceibacterium atlanticum|TrEMBL
MSYAAIHPDWEKPRTNMVDGYSLEMTAKEIEGLKEAAPQIRPGTQIAVTFLPGEEMDQRV
EAAVQVRELGFEPIVHLSARRIGSEEILDQYLSDITTKAGVKRVFIIAGDPPEPEGPYSD
SLQIIETGLLQKHGIQIVGIGGHPEGHPNVSKADLWVWMEKKIAAIREGGMVPLVVTQFA
FDDDAIVEWIEEMRQRGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGISLTN
LIGSAGPDKLVDSLDKKLNDAEHGRVRLHFYPFGALKASAEWINTYNNKHS
>N6XZU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera sp. 27|TrEMBL
MNTELSIEFFPPQTAEGAHKLRATCAQLAALEPAFFSVTYGAGGSTRERTFSAVKEIAAA
GHEAAPHLSCIGSTRDSIRDILQEYADAGIRRIVALRGDLPSGAGAAGEFRYANELVEFI
RAETGDRFSIEVAAYPEWHPQAKSPKDDLAAFKRKVDAGANSAITQFFYNPDAYLNFVEA
ARKMGITIPIVPGIMPIVSFSKLARFADACGAEIPRWMRKSFESYGDDSESIRALGLDVV
TRLCERLIAEGVPGLHFYSMNMAGPTIEICTRLGRSLRQD
>A0A1M6UUG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia thermophila|TrEMBL
MTAGEHLHRDRPVPVLDDFSLEITGRDADGLAGAAPLIPAGTRVNITYLGGETAQQRLAA
VRAVQELGFVPVVHIAARRLRSATELGEYVTALADTGAQTEVFLIAGDPATPAGPFPDSL
SVLESGVLQAAGVQRVGIAGYPEGHPDIPSPVLAGALRRKVALLAEQGLDTVVTTQFSFD
VQPVLDWIAGLRRDGVDAPVRVGVPGPVGIKRLLAYARRFGVKTSAGITRKYGFSLTNLV
GTAGPGAFVAALSDGLDPAVHGKVRTHFYTFGDVRATAAWVRAAA
>A0A423S5P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp. NJUB218|TrEMBL
MNASKALSLEFFPPRDAAAQEKLSVAARRLSALNPAYVSVTFGAGGSTREGTAEAVRLMQ
GLGFDAAPHLSCVGSTRSVLADILDAYRNTGVRRVVALRGDPPSGMGIDSGDLHYAVDLV
RFIREHSGDWFHIEVAAYPEVHPQAKSAQSDLDHFVSKVNAGANAAITQYFFNADAYFDF
VDRAQAKGVNVPIVPGIMPITNQVQLLRFSDMCGAEVPRWIRQRLADYQGDLASIKAFGK
DVITQMCQRLLDGGAPGLHFYTLNTAESTLAIANDLKLG
>A0A081RMS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marine Group I thaumarchaeote SCGC AAA799-N04|TrEMBL
MTIRYEANPPKILPDVDTDQSIKKFIERIKNISKKCDAIHLTENVLGFQRVSPLEVGKII
KEEIPDLPITVSLRVRDKSEEEIFEFAEKCVEIGFAGILVLMGDPSQTGKADSGQIPSLT
VKKLREKNVDSKINLYLSVSNKPNFAKLAKKKDARPKGFMTQVVQNTEQVQALSDNLKEF
SIIPIILFPSQKNEKSAKFLGLDLESYSKEFEELLRKSHEITGDVLLTSPNDFTGLNEFL
GKTTF
>A0A7C0ZHJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MGERESVLKEKLLDPNAFCITWEQIPGRGAFELQHEEVIDNVAKAAAGGKIDAISVTDNP
GGNPALSTEMLCVQIKNAGMEPLAHLACRDKNRSEIESLLCGLAADGVKNILVLTGDYSG
SDAFEGLAKPVFDLDPPNVLRLVEKMNEGLEHKAMRKTVKLAATDFFAGACVSPFKKLES
ELMGQYAKLKKKIEAGAKFIITQVGYDARKYHELLTWLRVNNYNIPVFVNIYVLPYGAGR
FMNSNGIPGCVVTDKYLAELAEAKKADDKGKAAMLLKSAKMYALAKGMGCAGAHIGGHGI
TYEQVEYIIDKGNELAANWESLVKEFDYPQENGFYLFEKDEKTGLNTDVYAQRPSKPSIP
FIYRFSRIAHHLLFEEKSAVYKTMKPIAAWLDTTHTPKHIFDFFEHMSKVAMFNCMNCGD
CALFDTAYVCPMSQCPKSQRNGPCGGSYDGWCEVYPNEKKCIWVQAYDRLKPYKEEGKIT
EYTVPPCDWNLWQSSSWLNFYQGRDHTAKRLGIKPPPKKESSKK
>A4T0E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter asymbioticus (strain DSM 18221 / CIP 109841 / QLW-P1DMWA-1)|TrEMBL
MELSVEFFPPKTPEGESKLHLVRERFSETLKPSFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
AETGDWFHIDVAAYPETHPQAKSPASDVDFFVQKIKAGANSAVTQYFYNSDAYFRFVDEA
YDLGVTQPIIAGIMPITNCTQLLRFSDTCGAEIPRWIRLRLQSYGDDIASIKAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLDLTK
>A0A800A1K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSLRESLKNGKFVVTAEVGPAKGVDIHEFMENAELLKGRVDAVNCTDQQSAVMRLGSLAG
CYLLKQSGLEPVFQMTCRDRNRIALQSDLL
>A0A7C7MHG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIIDILNSKKTISFEFFPPKRDSDLPKLHETVDRLSTYNPDFVSFTYGAGGNTRQLTTQ
VSKEAKLSDKFEVMSHLTCIAHNKTEIINILKDLTLSNIENIIALRGDTPKDMTISKDNL
KHATDLIEIIKSNFSNFCIAGACYPEFHPESNNSVDDIKFTKLKQDKGVDFLITQLFFDN
KDFLSFREKAIKHGITIPIIPGILPITSTKQIRRFTKLCGSKIPLKLNEKLENSINNDKE
TTKLGIEYATNQILELIDNDIPGIHFYSLNKTSSVGHVLNNLGISNQTPEYII
>A0A7C2C7G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MELPVLTRPLGEPSPLEARLAAGEFVVASEVSPPRRPRLTGFIRRARRLGRFAAALTVTN
NHAARPRLESLVAAYILRLHGIDPIWVVNTRDRNRLAIRSQILAAGVLGVQNVLCVRGDP
IEKGSDPEAKAVHDLSTLDLIRLFAEQKAEGHRFFIGAAVDVTSGPVDKAFKQARRRVEA
GADFIQTQPVFELGPIAELAARLRDLGERRPYLIAGLMPVLNLGDIGRVERNLGIPVPAS
VRERLARTSDPRGAGLELLAELVAGL
>A0A7C2WQA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSKLREKLELGEFIVTGEIGPPKGVDLDKCLDEAVALRGHVTAINVTDLQSAVMRIGSLA
VSAKLIERGLEPVFQITCRDRNRLALQSDLLSAWALGIENVLCITGDHPILGDHTEAKPV
YDLDSVQLLKAASTLNQGHDMSGHELESNPSFFLGAVVTPAAEPLEPQLIKMKKKIEAGA
RFFQTQAIYEPERFGQFVNQVQEFNVPVIAGIVLLKSAAMAKFMNSNVAGVNVPESIIRE
MEETAKEDRKKKAVEITARIIRQVKPFCQGIHIMPLGWGEMIPEILKEAEISQDVRSRRE
EV
>A0A501WE72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter mangrovi|TrEMBL
MKVTDHFQNANGKTLFTFEILPPLKGENMKTLFSHIDPLMEFNPPFIDVTYHREEYVYKQ
RENGLLEKRTTRKRPGTVGICAAIQNHYKVDTVPHLICGGFNKEETENALIDLHFLGIDN
VLVLRGDCVKSEQRFVAEPGGHNYATELIGQVVDMNNGCYLDDEQTFHNPTDFCIGVAGY
PEKHFEAPNLKSDLRWLKKKVELGAEYIVTQMFFDNQKYFDFVHRCREEGINVPIIPGLK
PMTTKTQLTLLPSLFHIEIPCELADAIEACPDNKAAAQVGVEWAIQQSRELMEFGVPCLH
YYSMGKSESVRKVAEALF
>A0A7V2LD19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAQSFKEALNSGKFVVTSEIGPPKGTNIENMRHHIDILKDKVDAINVTDHQSSVMRFPSI
GGCLEIKEHGGEPILQMTCRDRNQLALQAELLLAYTRGIRNVLCLTGDAVPVGDHKEAKG
VFELDSVQLLRAIRQMESGKDMGGNDLDGSVEFCAGAIVTPEANPIEPQLIKFEKKIEAG
AEFIQTQAIYDLDNFAKFMDYARQYPVKILAGIVLLVSARMAKYMNENVPGIFVPQHLID
EMAEAPKGEALNKGIEIAGRMIAELKKYSICDGVHIMAIGREEVVPDILAAAGIDNHNK
>B8DUK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium animalis subsp. lactis (strain AD011)|TrEMBL
MHTPMFSLEVFPPKRTSPVGTIYDTLDGLNDMKPDFISVTYGTGKSADRTATARIAHTIH
SEYGIDAVAHLTAQYLTARDVDEALAMFDEAKVSGVLALRGDRNSEREPAGVFTHASDLV
CYIRERRPNLKIYGACYPEKHPQAATLDEDVANLKAKVDAGASHLISQLFYDDDFIAFLG
KARAAGIDVPIEAGIMPVTNAKSVRRMTNMCSSRVPRKLERMLEKWGDDPRTLREAGIIY
ASEQISDLVAQGVDGVHLYTMNHPSVSRRIWQNVGNLFEKA
>A0A7C1F3H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTGDYPVSGFTGRAKPVFDLDPVHTLKLITELNNGLEIEAMGKTQKLQPTDFFAGCAVSP
FKRDEAEQMVQYFKLKKKVEAGAKFIIPQLGYDIRKFHELIQFVRENGWDIPVIGNVYIL
PYGAAKLMYENKVPGCVVTKELLSVLEKEKDAPDKGKQARLDRAAKMYGFFKGMGYDGVH
IGGHGVKLEEVEYIIDKGEEFAKNWMDYVHEFQFPMPNGFYYYEKDEKTGLNTKTPTNRK
NRPLDTTVPAMYSFNRFMHELMFEPGKGLFGMMRSIVKSIDGSSMEHAFTRFEHLIKVVL
FDCENCGDCALFELAFLCPMSQCPKKQRNGACGGSFEGWCEVYPNKKKCIYVRAYARLKK
YGEEETLRDIYVPPANWDFYHTASWINFFLGRDHVGRRLGVPYVPPKKSSK
>A0A4U1KDW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azotobacter chroococcum|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMTVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRSLLNTYQNAGIRRIVALRGDLPSGMGMASGELRHASDL
VAFIRAETGEHFHIEVAAYPEMHPQARNFEDDLRHFAAKMQAGANSAITQYFFNADSYFH
FVERARKLGVEQPIVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFG
EQVVTQMCEKLLDGGAPGLHFYTLNQAEPSLAIWNNLGLPR
>A0A2H1HXV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. 239c|TrEMBL
MEATTATKVLDDFSLEMTGKDIPSLQQAAHAIPQGTRVNVTFLGNENLQMRVEAANEVLE
LGFVPVPHISARRLKSETELREFLDALQQAGASDHVFVVGGDPATPEGPYPDSLSVIRSG
ILQDYGVREVGIAGYPEGHPDISTETLWEHMSAKTESLTEQGLGQVVLTQFAFDAAAVVA
WVHEVRGCGIEADLRIGTPGPAGIKRLLGYARRFGVGTSAGIAKKYGFSLTNLIGTAGPE
RFLKDLTSYESITSASSGVKTHFYTFGGLASTAEWVQDFTAQA
>A0A419FJ94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MPKIADLLAQGRTLSFEFSAPRDPEGERRLSRVLGRLSALQPSFMSVTYGAGGSSRGPTP
EVVRQIIALGVTAMPHLTCVSHTRDEIRTLLDVYAAMGVENLLALHGDLPEGATEVPAGH
FTRAIDLVALARLRTDWSIGVAAHPEGHPKATDAASDIEHHREKLAAADFAITQFFFRAE
YYERFVEAMAKRGVRTPVIAGIMPPTNVEGIGRMSAQNGTEYPREIVARLEAAGDDVDAR
RAIATEEATRLGEALLAAGAPGLHLYTMNFSEPSRTIARNLGLA
>L0KM68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium australicum (strain HAMBI 3006 / LMG 24608 / WSM2073)|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHQVDAVIQEFTDMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGSELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEVAGS
AAA
>L8DHR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. AW25M09|TrEMBL
MTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRGITNILVL
RGDPPGDPLGHWEKHPDGVEYAEELVRLVRDLGDFHVGVASFPEGHHRADDLEQDTRGLV
GKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDAEQGAKPIIPEIMPITSLRSVRRMLELS
GTTLPSYLDEKFIRAAGSGPEEDRAAVREVGIELATTIGERLISEGAPGLHFITLNFARA
TREVLSNLGLAPARV
>A0A2G6CRN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKSGSNLERILHAGHFAFTGELGPPRGSNVAAVREKAQPLVGNVDAVNITDNQTAMVRMS
SWAASLIAIEEGLEPNYQMVCRDRNRLAMQADILGASALGIRNMLCLSGDHQQFGDHPQS
KGVFDIDSTQLIGTVKKMRDEAQFLGGADIDEPPRIFIGGAANPFAEPYAWRVHRLAKKV
AAGVDFVQTQCIFNMDRMRQWVKAAVDMGLTEKVYILAGVTPMKSIGMARYMQNKVPGMD
VPNEIIKRLQGVDKKKVADEGIKIACEQIEEFKEMEGIAGVHLMAIEWEHKVPEIAQRAN
VLPRPVV
>A0A3D1ZCI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
PIPVATTRDMLIFLYLRRRCASKFMRHLMKISDILKNKRTLSFEFFPPRDEQGVERLFET
IDHLKRYEPDFIDITYGAGGSTQRLTVELCVRAYRDSGVTVMGHLTCSAQTKEMVHSVLK
RFESEGIENVILLRGDPPQGEDTFVPAEDGFSHATDLVQHTKENFDFGIAAACYPEAHPE
SLDADSDLYYTKMKVEQGAEFLITQLFYDNEDYYAFVDRARQSGIDVPIIPGLMPILNAS
QIRRITSLCGATIPAGLDRQLERHADDNRAVRQIGIDHTLRQAQELMGSDVPGIHFYVLN
RRYSITKILDNLQGSSVGVTSS
>A0A523P6L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSQEHRLTTFSTALKSKAFVVTSELNPPKGTDLTKLYEVADRLKDYVDAFNLTDSHNARM
SVAPMAVAHMLHDRGIESIVQVTSRDRNRIALQADLLGAAVLGINNIVVMGGDPPSYGDH
PEAKPVFDVYAAMIIEAARALENGTDLTGNALNGTPKFCVGAVVNPGATNITDEIKRMEE
KIEAGADFLQTQAIFDPGAFETFVKRTKSLNVPVLAGIIPLKSAKMAAYLNAKVPGIHVP
DALIREIDDAVEPDITSATIAARTIKALRGLCQGIHIMPIGRERLVPRILEEAGVGSSPS
>A0A1M5TRP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis glycolicus DSM 9705|TrEMBL
MKTDSYLEKVLAAGHLAVTSECGPPRGATAASVQDKAKYLDGVVDAVNITDNQTAMVRMS
SFAGSVLVRQQGMHPLLQMVTRDRNRLAMQADILGAYALGINTMLCLSGDHTKFGDHPMA
MNVHDIDSIQLIQMVKTMRDEGKFQGGAEIKGAPKMFIGAAANPFADPFELRVMRLAKKI
AAGADFIQTQCIFNIEKFERWMEGVRKMGLHKKCYILAGVTPMKSVGAARYMKNRVPGMD
VPTELVERMGSVEKEKQPEEGIAICVETIERLKQVEGVAGFHIMAIDWEEKVEEIVKKAG
LYPRPQVQ
>A0A523P3D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MQKAQEQKTFSFELFPARSAEARGKLELTCKRLSALKPDYFSVTFGAGGSTRELTLETVL
AVAEATGVDSAPHLSCIGYPLEKIRAVLQGYLAQGIRRVVALRGDMPSGTTGVGELRYAN
ELVEFIRSETGSAFHIEVAAYPEFHPQSNSAAADLNNFKRKVEAGADSAITQYFYNPDAY
FRFLDSCHKLDIDIPIVPGIMPIINYTQLSRFSEMCGAEIPRWIVSRLRDFGDDRIAIRA
FGIDVTTELCRRLLDQGVPGLHFYTMNQYEASEAIWQNLGIETSHSESRRGETTEN
>A0A4U6N7U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. NamB2|TrEMBL
MGDPSIHVEVIPSEGLPERLRAHLPAPAVVTVTCLPQHGPSEAVRAAVELAGAGYTAIPH
LAARSVHSRQELGEYVDRCLGAGITDVFVVGGDAADAAGPYRWGGALMEDVAELSGGALR
IGIAVYPEGHPGTDEEELARTLLGKQELASWCVTQLCFSPDTLRRYPSQLRRQGITLPVW
AGIPGPVRMSRLLRLAGKIGVGPSLGFLRRSAGSANAGSVVRQLLSSASYDPSPLVAALD
DAGYAGLHVYSFNDLAELAASDVTFPAR
>A0A1F9RBF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium GWA2_62_23|TrEMBL
MRLPERLKTGGKVYSFEFYPPKTAEDTAKLFNTALELKALSPDFVSVTNSSSGVTPYRTV
ALCGVLKAQFGLEIVAHLTCLAHTKQEISEICDGLKKMDITNILALRGDPHNVDAGARRS
DYSHAAQLITDLKRAGGFSLGGACYPEKHPEAGTLEADIARLREKVDAGAEYLITQLFFD
NAHYFRFLEKIAAAGINVPVLPGLMPLTGYKQMQNFTKMMQVGIPDELRRGIERWEGDKD
GLFKFSVDYASRQALDLLKGGAPGLHLYTLNRSRAAMAILQNVKGA
>A0A4R5DZY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. 6K520|TrEMBL
MRRLRPDRPPIVRELLASGARSFSFEFFPPKTDKGALNLWRTIRELESLQPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVDHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVQHPDGVEYAADLVRMIRSYGDFCVGVAAFPYKHPRSPDIESDTRYFIEKCRA
GADYAITQMFFRAEDYFRLRDRVQAAGCDVPILPGIMPVTQMSTIERSEQLSGAPFPPEV
RARFEAVADDPEAVRRLGIEHAAELCRDLLEQDAPGIHFITFNKSTATREVYGLLDAASY
GGRGSAPPMTA
>A0A1F9A2I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_43_22|TrEMBL
MPDPSKFAQALGTDSFIVTCELDPPKGFVPSLLDRKIAVLKNKVQAVVVSDNPRARMLMA
PVGFCRYLLDQGLELIMTLTCRDRNRLALQSDLLAAAGLGIQNILAVTGDYITWGDHPEG
KPVYDLDSIQLIWAISQLNSNRDISGNVIEGTAPSFTIGSAVALTGNPVGPQVLKFRKKE
KAGVHFFMSHPVFDLADVEEFFKQVVEIQTPLLASVCLLTEEQIRGYVLGNYPGLLIQDS
LSDKFKSVHSTEFQPRMIEHTARLIETIKKDGRFRGVHLMLQGAEEQIGELI
>A0A1Y4S891|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp. An131|TrEMBL
MKITELFERGEFVVSAEVGPPKGFHVEHLLEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKALKDEGLNPIFQLACRDRNRIALESDLLSAAMFGIDNVLCLTGDHTKLGDHPQAKPVF
DLDSVSLLHTVAKLEEGEDLGGNKLVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQLGIIIPKSAGMVKFMNNNVAGIHVPDEMIEE
LKADPEKAKAGITGVEIAARIIKECKPYCQGVHIMALGWESKVPALLEAAGL
>A0A0C3MSH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira sp. NpAV|TrEMBL
MESQKKFARTFSFEFFPPQTREGIEKLRATRAQLAQLNPKFFSVTFGAGGSTRDRTLETV
LEIQAEGYAAAPHLSCIGSTSENIRAMLQKYQDGGIRHIVALRGDLPSGMAQWGEFRYAD
ELVRFIRKEFGNAFHIEVASYPEYHPQADSAQDDLVNFKRKVEAGADSVITQYFYNADAY
FNFIEACEAMGVNVPIVPGIMPINKFSQLARFSDSCGAEIPRWIKKKLEGYGDDSASIRA
FGLDVVTDLCDRLLSAGAPGLHFYTLNSAGLTTTIWQRLGL
>A0A0K8P4X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ideonella sakaiensis (strain NBRC 110686 / TISTR 2288 / 201-F6)|TrEMBL
MNPIPISFEFFPPNTPVGDEKLKTVVQDLGALAPEFFSVTYGAGGSTREKTLATVAAIAR
SGHEAAPHLSCIGASREGIAEILGTYRAQQIRRVVALRGDLPSGTATSGEFRYAADLVRF
IRETQGADWRIEVAAYPEYHPGERYAARDLEHYAQKVHAGASAAITQFFYNPDAYFHFVE
ATRRLGADVPVVPGIMPFHNFAKIAQFAQRDGIEIPRWVALKMEGYMDDAASVRAFGLDV
VAGLCERLIAGGAPGLHFYTMNQSALTLELCRRLGLGAAA
>A0A2W4RA36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTLEEKIRAGRFVVTTELTPPKGTDLGELLSRAESLRGHVDAINLTDSPRARMTVEPKSV
GRLLLERGIEPIVQITARDRNRIAIQADILGASVLGIRNLVFMGGDPPQKGDHPDARGVF
DLTAAGMLEAARGLMQGHDLAGNPLRGAPELFLGATANPGAADLAAEVENTRRKIEAGAQ
FLQTQAIYEASPLERFLEALRADGVAVLAGVIPLKSAKMAAWLNANVPGVHVPEALFTEM
QTAADEGQEAARGIEIAARIVRTVRPLCAGVHLMTLGWEEHIPQILRSAGILSSSAGSL
>A0A524ARP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MANSLFEEKLNSNGFLVTTEIGPPKGADVSEMVHCIDLLKDKVDAINVTDHQSSVMRFPS
LGGCLLVKECGGEPIIQVTCRDRNRLALQADLLLAYSRGIKNVLCLTGDSVDVGDHKEAK
PVFDLDSVQLLKMARGMESGKDMVGNELKGTPQFCLGASVHPEADFIEPQLIKFEKKVIA
GAQFFQTQGIFDLESLKKFMQYASQFNIKILAGIIVLASARMAQYMNDNVPGIIISQAII
DELANVEKGKGLQKGIEIASQFIRTIREENLCHGVHIMAVGKEGIVPDILEAA
>U9Y5Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 113303|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A418TDV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. 1011MAR3C5|TrEMBL
MGVEQLRRPDLREALAERILVGDGAMGTYLYQMGFPVGVSYEEFNTLKPEVIESVHRHYY
EAGARLIETNTYSANLEKLSRHGLEGEMEAINRAGVRIARSAVGADAYVVGSVGSIRDGK
LKNLRTKRVIDAYEKQMKVLVEEGVDGLLLETFYDLEEMKLAVRIARELTDIPIICQFAV
EDSGRTADGVALADAFSQLQALGADVVGFNCRSGPNGIMRSMDSINASVALPFSVYPNAG
IPDYVDGKYTYSAGPDYFAECARKFADRGARIIGGCCGTTPEHVAAMAASLENYVPQPGA
AAAAKRQATLVRESAPKQSEQGSYGDIHQQPSLVDLVKERHTVIVELDPPRDLDIRKFME
GAAALRDAKADAVTMADNSLAVTRMSNIALAALLQEKIDIRPLVHIAARDRNLIGTQSHM
MGLDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGVAFSGKPLKQKA
KFVVGAAFNPNVKHLDKAVQRLERKIASGADYIMTQPVYDTGLIERIAESTKHLSVPVFI
GIMPLANGRNAEYLHNEVPGIQLSDDVRARMTGLEGPAGRAEGVQIAKELLDCALQHFNG
IYLITPFMFYDMAVQLTQYVWEKTKR
>C0B744|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus comes ATCC 27758|TrEMBL
MRIIDKIKADGVHISFEVFPPKTDAGFESVLKATDGIAELTPSFISVTYGAGGGTSKNTV
KIASHIKNDLKIPALAHLTCVSSTKEEVHKVIGQLQKEGIENILALRGDIPQDGQFPLPG
QYSHACELIEDIKKMGDFCIGAACYPEGHVEMEHKKDDIRYLKEKVDCGVDFITTQMFFN
NDIFYNFLYRIREQGIMIPVLPGIMPITTKKQLARSCALSGTAVPQRFRAIVDYFGDDPA
AMKQAGIAYATDQIIDLIANGVRNIHVYSMNKPEVAAAIMQNLSEIVK
>A0A2P4XQ82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora palmivora var. palmivora|TrEMBL
MGLALQPTFVTLTWRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEELKRVLKNAR
AAGIRNILALRGDPPIGAERWAPVEGGLSNAVDLIKLIREEHGDYFCIACAGYAEVHTES
WNHPDLPPSNEARALDLQRLKAKQDAGADFIITQFFFDVDNMIQWIADCKDAGITIPILP
GYLPIQNYSSFCKFTSWCKTRVPENVLTDLDAIKNDDAAVRRYGTQLAVETCERLLAAGV
NSLHFYTMNLAATVTQVLEGLQLLPARNQRDLPWQSTLHRSTVEGEQVRPIFWSNRQASY
IARTAAWDEFPNGRWGDRTSPAYGELSEYYLAFKRPKLQRAELWGTPQSEEDVWNVFVRF
IDGHVKQLPWCEQSLSLESAAIRENLQWLNSNGFLTINSQPRVNGAPSSDPSVGWGGDNG
IVFQKAYVEFFVAPEKMAHLVKVMRRDYPQLSFHALNRQGDEHRNTPLHSVTAVTWGVFP
GTEIVQPTVVDSDSFAAWKDEAFELWQTQWASAYPEGSRSREVIQHVYDTYFLVNIVDND
YANDESDIFNIFTRIITEAMDKEQLRARVLELEARREKMFDTLASFQSLQEELNGELRAA
HSELAGVRSENLQLKDKVRELQSQLALTSL
>B5ZWL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii (strain WSM2304)|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGVSIPVVPGIMPVQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGINEFHLYTMNRAPLVSAVLDNLGFSRRAAKSAGAAA
>A0A7C1Y343|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium|TrEMBL
DMPTIGAPYAPDPDGYVNAADLVGGLKKIGDFRLSVAAYPESHPDSENVEADIDNLKRKI
DAGADQAITQYFFDVDMYLRFMDRVLAAGITVPIIPGIMPVTNFAQAKNFSARCGTSIPK
WLEKLFEGLDDRPEIRRHVAATVAAEQCMRLYRGGVKQFHFYTLNRSELTATICHFLGLR
PTGDAS
>A0A498DE57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanobacillus piezotolerans|TrEMBL
MDLLAAMKERILIGDGAIGTLLYSYGVDRSFEELNLTHQEQIVNVHQAYIKAGADLIQTN
TYAANYLKLSRYGLEDQVKKINTAAVRHATQAAGDQAYVLGTIGGIHGTQSFASKEEIKR
SFREQLYCLLTEKVDGLILETYYDLDELTTVLEIAREETDLPIITNVAMHEPGVLENGIR
LPDALKHLENSGADIVGINCRLGPYHMVKSLEDVPLSNKSYLAAYPNASLPAYHNGKLIY
ENEPDYFKSCAKDFRNEGVRLIGGCCGTTPEHIRALAEGLKNLTPIKEKQIHMESTPIQL
KEKQVQTKTPLPEIAKKQHSVIVEFDAPKHLDTTEFMEGVKALNEAGIDAITLADNSLAS
PRISNMAIAAKIKQEIGIRPLVHVTCRDRNLIGLQSHLMGLSTLGIHDILAITGDPTKIG
DFPGATSVFDVISFDLIKLIKQANNGMSFSGKSLRKPTSFHVAAAFNPNVAKLDKAVERM
EKKITFGADYFLTQPIYSPDKMIELSKATRHIDKPIYIGIMPLMSARNAEFLHNEVPGIK
LTDETRARMRAVSANKQQSVEEGIAIAKELINTAMEYFHGIYLITPFTRYDITVRLVDYI
NEKVQSVTGKQTLRAIHHH
>A0A3N7D2W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. KBW06|TrEMBL
MKIVDHISNAKGKPLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HPNGLLEKIAYRKRPSTVATCAAIMNKYNVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDNSFVPTPDGHAYASELLQHVVDMNNGRYLHDYMEDAAKTDFCIGVAGY
PEKHYESPNLDTDFKYLKHKVDTGADFIVTQMFFDNKKYKALVDKCRANGINVPIIPGLK
PITSSKQLVSLPKIFHLDIPMELTEAIQACKSEKDVKEVGIEWMIHQCQELKEMGAPVLH
FYTMGNPEPTKKIVQAVF
>A0A4Q5S0P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium|TrEMBL
MTEVNPLAAPLFADVAGDIDVSFEFFPPKTEKMEETLWESIQTLSPLGPRFVSVTYGAGG
TTRERTHNTVARIAAETGIPAAAHLTCVEATREEIDQVANEYWNAGVRHIVALRGDPPRA
GEKYSTHPGGYENAADLVSGLLKLHPFEISVAAYPECHPDSPHATADLDNLKAKIDAGAT
RAITQFFFEPETFFRFRDDAAAAGITAEIVPGIMPVMSFAAVKKMSAMCNTDVPAWMERL
FQGLDDHPAARQLVSATLAAELCRKLYAGDVRQFHFYTLNRAELSYAICHLLGVRPK
>A0A373XS70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF17-11|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A5C6CIU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bythopirellula polymerisocia|TrEMBL
MTTLAQAYGPERFGLSFELFPPKTDAGIENLWFHVDRLVQFQPSYITCTYGAGGATQDRT
LEVVAHVRSKFELPVATHLTCVGNTADQLRAYLHRALELEVDNVVALRGDPPRGETAFQS
VEGGFSYASELVQFIRDEFKNMGIAVAGYPETHQEAVSPEADLANLKRKVDAGADIIITQ
LFYDNVDFFAFRDKCQAAGINVPLIPGLLPVTNAAQIQRISSLCGAKLPPDFLAALSKHE
DGSAGQFEVGVEFATRQTAELIAEGVPGIHFYVLNKSEATERVLSDVQLPR
>A0A0T9QKR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pekkanenii|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTKIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A413RH88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas rhizosphaerae|TrEMBL
MSAATVEPRTPAAHAAPALRPLASVDRPTVSFELFPPRNPHAAPRLWETIRAIEDVRPDF
VSVTYGASGKTRETSRTLVTQLLRETTLNPIAHLTCVGTSRAEVTAIVEEFLDEGVRSFL
ALRGDPPADQPDWQPHPDGLNTAGELVELLREIESQRCIASPSQAVRARVRPLSISVAAF
PRGNAATGGTRAQDVASLLAKQEAGADFAITQVFFDADAYLGLVAEAREAGVVIPIIPGI
IPTTDPARLLRVQELTGVPVPRTLLDLLGNADGEADQHRRGIRAGIDLINGVLDGGAPGV
HVYTFNKHHAALDLLEGAQLHGGAGTSSRAAAATDPAPAAPTTPEG
>A0A838SQG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidothermales bacterium|TrEMBL
MTDSATTAGGVMSSGSTGQRRREALARALRRPRYEVLPLAGTADQVEQHVPRDLPVTVTA
SPGHGIEPTLSLTETLVRRGFQAVPHLAARLVRDEAQLTEILQRMEQAPVRDVFVVAGDG
QRPVGDFTDSLALLTAMQRLRQAGVGRRLERVGVAGYPQGHPIIADEELTRALHAKQPLS
SYLVSQMCFDPRAVSAWVTQMMELGLRMPVHLGVAGVVDQRRLLRIATRIGVGSSAQFLR
KHRYGLVRLALPGGYRPDRLLRQLAVELAEPARPVVGLHIYTLGDVAATERWRRRALAGL
TGDEPRNG
>A0A3S0XA17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. VKPM B-3276|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2Y9GJ70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neomonachus schauinslandi|TrEMBL
MVNEPGGDGGPPPRSEGSSSGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSQEQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAVDLVRH
IRREFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDDAIRNYGIEQ
AVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFEVFACYLSGEPNQHGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPTPEQGAEAL
>A0A7L4N3M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceyx cyanopectus|TrEMBL
LPRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNFCGLETILHMTCCNQTKD
DITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDICVAG
YPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLKFMKDCQAIGITCPIIPGI
FPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGVVH
GLHFYTLNREVATIEVLKRLGIWNEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIY
RTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVFT
CYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNINGKPSTDP
IVGWGPSGGYVFQKAYLEFFTSSEIVTALLRVLKRYELRVNYHIVNVKGQNITNAPDLQP
NAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNY
YLVNLVDNDFPLENCLWQVVEDTFELLN
>N8RQX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter parvus DSM 16617 = CIP 108168|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLHIVHQELQRLNPEFFSITYGAGGSTRERTLATIHDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGNHFHIEVAAYPEMHPQADSFDADIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERLEKEGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1Y3C8F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 3903|TrEMBL
MSKRVPISFEFFPTKTDVGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGEHFQIEVAAYPEMHPQAESFDKDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVNLCERLLAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>V6JPZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces niveus NCIMB 11891|TrEMBL
MALGAASIRTDHARTVRDLLATGKLSYSFEFWAPKTEKGERNLWNALRRIEAVAPNFVSV
TYGAGGSTRAGTVKATQRIAADTTLVPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPRGEWVKHPEGVEYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWESDIRHFVA
KCRAGADYAITQMFFDPEDYLRLRDKVSAAGCDTPIIPEIMPITNVRQLERFSQLSNAVV
PPALKERILSVKDDPAAVRSIGIEYATEFCATLRAEGVPGLHFITLNNSTATLEIYENLG
LHEQS
>X0D988|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. raphani 54005|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDDVKGDDERVKMVGVDIVSELIDKIKTIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A1I6RSX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter marinus|TrEMBL
MPSPAVSFEVFPPKSVDASFRLWDTAQALAPLSPRFFSVTYGAGGTTRDLTHDSAHVLRR
TSGLPVAAHLTCVGASKSETMEVANSFAEIGVTDIVALRGDPENGASVFTPHPDGFANSV
ELIEALTATGNFTLRVGAYPEPHPESVDQAQNIEWLKRKFDAGADEAITQFFFEADTFLR
FRDDCAAAGITKTITPGIMPITNWKAARGFATRCGTQVPAWLDDAFETAIRDDRHDLLST
ALCTEMCSTLVDEGVENLHFYTLNRPELTRSVCRALGVTAQTSLSDVA
>A0A3P1V5J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces bowdenii|TrEMBL
MDGEDRVTHSEDPHRAAGGPARPTVSLELFPPRPGRAAPATWSRIDSLLATGPDFVSVTY
RPAFVAGAAEPGRGPAGVRVVNEPNPAEQVVEHILSTSTVPLMAHLTCIGYRRSDVVEIV
THFLGMGVRRFLALRGDPPPGASPDDLAGELPHADDLVRVIREVEDEYFGDGRRHVTVAV
AAYPVTTDHALAIEVLAAKQAAGADLAITQVFYEAEDYAALCRAASYAGVTMPILPGLIP
LTDLGRLTRLESLTGVPVPEGLRASLSSAHGAELVGRGLDATLELATALLEAGAPGLHLY
TFNRTRPALDVISHLRLGGILSGSAPDPRVREAIERGYLQATPGRGPSFLRAAPCASEPA
APAGPAPTTTKEIT
>F2NW06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091)|TrEMBL
MTISKILEQKKTLLSFEVFPPKQQANFENTVNAAKELCNLNPDFISVTYGAGGTTRENTV
EIASKILSFGTPALAHLTCVGNTIDEAKNIISQMKKNKIENVLALRGDIPQGIPNPLSNE
LDHANVLAKILKDEGFCVGGACYPEGHPESHNRQEDIDNLKYKIDAGVDFLTTQMFFDNN
MLYSYLYQIQSKGIHVPVLAGIMPITNSNQVSKMVKLSSAYIPAKLLSICDRFSENPEAM
RQAGIAYATDQIIDLISNGVRGIHIYTMNKPSVAQEIYKNVDKIISAINS
>A0A2S5GX64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter spanius|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGATRQDLRDILQTYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSLDLDHFVAKVNAGADAAITQYFFNADAYF
DFVDRAQAKGVKVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPLAVWKELAL
>V6KNK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces niveus NCIMB 11891|TrEMBL
MPIRDLLAAGGRSYSFEFMPPRSAAAEAGLWTAIRRLEALSPAFVSVTYGAGGSTRGRTI
GVTGRIAQETTLTPVAHLTAVDHSVAELRNILGHYADQGVHDILALRGDPPGDPLGPWTK
HPQGLEYAAELVQLIKESGNFCVGVAAFPEMHPRSTDWDSDIRHFVDKCRAGADYAITQM
FFDVDDYLRFRDRVEAAGCTTPIIPEIMPVTTIRSLRRIPSLSTAVFPAGLAERMLAAED
DPKAVRALGIDHATEMCRRLISEEAPGLHFMTMNFSKVTTEIYQNLGLHH
>A0A495KTT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis sp. Huas11|TrEMBL
MLAAPTRPVALRNPTPRPRHIRELLHAGEPLFSFEFFPPRTPTAQERLWRAIREIEALGP
SFVSVTYGAGGSTRGMTVETTERIATDTTLLPVAHMTLVDHSVAELRHLIGRFADAGVSN
MLAVRGDPPGDPDGEWVRHPQGLTYTEELVRLLKDSGDFCVGVAAFPYKHPRSADVETDT
DHFVRKCDAGADYAITQMFFDPEDYLRLRDRVAARGCEVPIIPEVFPVVRTSFIPRSEQL
SGAKFPAELAAKFESFGDDAESVRAFGIEYAQRMCQRLLAEGAPGIHFITSNRSTATRQI
YQEVSGRRSRSTGAARP
>A0A8B4C0S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myroides odoratimimus subsp. xuanwuensis|TrEMBL
MKVTEHIQKANGKTQFSFEILPPLKGQNIQGIFDSIEPLMEFDPPFIDVTYHREEYEYKE
AGNGLWEKRTVRKRPGTVGICSAIQNRFKLDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKNETYFKPEPKGNKYASDLVTQISELNQGIYLDPELENTSKTDFCVGVAGY
PEKHMEAPNFDTDLKYLKQKIDNGAEYIVTQMFFDNSKFFAFVDKCRSIGIDVPIIPGLK
PLATLSQLNLLPQRFKVDLPDDLVAEVLKAKDNAAIREIGIEWCAQQSRELIEAGTPIVH
YYSMGKSDNIKNIIKLATV
>B3T3B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured marine crenarchaeote HF4000_ANIW97M7|TrEMBL
MLLIYRSKVLITYNQKPPMTVRYEINPPKISGDGQDVRNVLFERIETISSVCNGIHLTDS
VLGIPRVSPFKIAKQIRESNKNIKLTCSLRVRDKNLNDIEKIVQESIGTVDGILVLMGDK
SDTMPNKDNLIPSQVVKALNDNGLDKKIELFLSLPSNPNFAKIQKKIDAKPVGFVTQVIH
SKDQVEKIVNYLRPNGFKIIPCLLLPSKNNLKSAEFLKIDWSNYEENIIEFINEIHSITS
EILVTSPNDFKRAHETLTKLAT
>A0A6J4WNN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium diphtheriae|TrEMBL
MSAQPLPAAYQRTITDVISIPTPGQVPFSVEFMPPRDEAAEERLWKAAEAFHDLGASFVS
VTYGAGGSSRERTMRVAHKLSRHPLTTLVHLTLVEHTQEELEEILCTYASHGLSNLLALR
GDPPGTDPMAPWVPTAGGLDYAKDLIDLVRKTEQTSHFQVGIASFPEGHYRAPSIEADTQ
FTLEKLRAGAEFSITQMFFDVDHYLRLRDRLVKADPEHGSKPIIPGLMPITSLRSVRRQM
ELAGATLPKALEKRLLDAARGDEEAHRGDIRKVGIEVTTEMAQRLIFEGIPDIHFMTMNY
VRATQEVLHNLGMAPAWGTQQGHDAIR
>I3DM55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parahaemolyticus HK385|TrEMBL
MSFATDIDHLNQNIADLNGKINVSFEFFPPKNEKMENLLWDSISRLAPLKPKFVSVTYGA
NSGERDRTHSIVKSIQQETGLIAAPHLTGIDATPDELRQIAKDYWDNGIRNIVALRGDEP
KGYAKKPFYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRAIS
QFFFDIDSYLRFRDRCVNVGIDVEIVPGILPVTNFKQLQKMAKITNVKIPNWMYRMYDGL
DDDPTTRNLVAASIAMDMVRVLSKEGVKDFHFYTLNRSELTYAICHTLGVRP
>C7M2P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP)|TrEMBL
MSDVLDRYGERVCSVELWPARTSDQEHRLTATLDVLRSLPPAFVSVTYGAFGSSRHESLA
LIERVLADGHRVLAHLAVAGHSPEQLVALLTHVERLGADGVLALRGDPPLDDPDDRARFV
GRHALELVELARQHTQLSVGVALHPSGHPEARSLEDDLDHQAAKLARADFGITQFYFEAA
ALTRLRGALRGRGVTRPVIPGLLVPRSPRQLLRMGEMAAVRVPRELVEALEGPDGPARAR
TVVGELASAALEEGSPGVHLFSMNQPETTAWLLERLDRRHRRVS
>A0A2E7F1H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ponticaulis sp|TrEMBL
MSLQHAPKDIHVSFEFFPPKSEKAEDTLWESVRRLEPVHPKFVSVTYGAGGSTRDRTHRT
VKRMVEETDLTPAAHLTCVSASKDEVMGVVDDYLDAGVRHIVALRGDPPEGMGAKFTPHP
EGFQSSVDLISAIRHYRPELGKRFEISVAAYPEPHPDSLGLAKDLEILKAKQDAGADRAI
TQFFFEPDHYFEFLDAARGYGIDIPIVPGIMLQPNFNGLKRIATLCGASLPAWLHELYEG
LEGDAEQRELITANVAADLTMKLADRGVKDFHFYTLNKAGLSLATCRLLGIKPEKQAA
>A0A3M0A3R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium weaverense|TrEMBL
MKVTQHIEESKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVD
KGNGLLAKRLTRMRPGTLGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGINN
VMALRGDAMKDEQSFVAKAGGNNYAVDLVNQIYHLNQGKYLHDVMHVDNKADFCIGVAGY
PEKHLESPSLLSDLKRLKEKVDAGADYVVTQMFFDNAKYFQFVDKAREMGITVPIIPGIK
PLAVQRHLQVLPQIFRIDLPEDLIRAVDDCKDNAAIREVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A4R9JZU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira sarikeiensis|TrEMBL
MKKILEIYKEAKGPVYSFEFFPPKTPEGETKLFEAVGELSKVEPGYITVTYGAGGSTREK
TIRITSELAKKFSLPAAAHFTCVGGNRDEIRVILKQIRESGIENLMALRGDPPKGEGTFK
KVEGGFGYANELISFIKDEGFDFCMGAACYPEKHPEAPSLDFDLDNLKRKVDAGASYLVS
QLFFKNSIFASFLDLIRKKGISIPVIPGIMPITSFSQIERFKSMAACEFPDKLVADLEEV
KDKPEEFYKRSVQFSVNQCRELVQMGAPGIHLYTLNQSPASLDIVRELKS
>A0A2X2M3D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseus|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVRA
TQQIAADSTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>B7AVK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Bacteroides] pectinophilus ATCC 43243|TrEMBL
MCDCRPDYISVTFGAGGSSNNNKTIQLARKIKEKYHVEPVVHLTCLCYNRAEIDEFVREL
TAEGIENILALRGDRNPDVPAKEDFAHASDLIKYLRATTGDRFCIAGACYPDVHPETGNR
VDDINNLKIKTDAGADILISQLFFDNDTFLQFVSDCRRARIEVPIVPGIMPCINAAQIQR
MVTMCGAKFPERFRKLIRKYGDNKDALLMQEWHTARAR
>A0A818GX59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MASYEEDLRYLKEKVDYGADFIITRLFFQPATFIKFESDCRSIGIQCRIIPGIFPIQAYA
SLKNIVRLAKLDVPEEILACIEPIKYNGEAIRNFGVQKCVDLCRTLLDSGKIHGLHFYTL
NREYATIEILRKLDRWLEDPPLRALPWKTISKKYSVRPKSYVHRTSNCEEFPNGRWGLSF
APSFGVLTDYHLFYIKIDATRDALLDEWGHELADKQDVRRMFACYIADEKNGRVKIVHHF
PWKDEDISPETNFIHDHLIKYNRKGILTISSQPAVNGKSSTDSIFGRGIKKWLCLSKKFF
TSEKKIPALRTVLKKFPGVNYHFVNKSGEVNETSTEGEQPIALIWGVFAGREIIQPTVVG
PISFMIWKAIDLSARLINDYFSIL
>D4LB75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus champanellensis (strain DSM 18848 / JCM 17042 / KCTC 15320 / 18P13)|TrEMBL
MKTCELFRDHTVLSFEIFPPKPTSPEDTIYRTLDGLRDLHPDFISVTFGAGGGANNQKSL
EIASAVKHQYGIESVAHLPGINLTRSEVLTMLEQMQQQGIENILALRGDVLPDTQPRGEF
RHADELISFIREHGDFNILAACYPEGHTESPDTVTDLRNLKRKVDAGANQLVTQLFLDNR
YFYEFREKAELVGIHVPIEAGIMPVTNKKQIERMVQLCGVHLPDKFMKVMNRYEHQPEAL
QDAGIAYAIDQIVDLITQGVDGIHLYTMNKPYVARRIYEAVHRLLYA
>A0A6G2PZ80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID685|TrEMBL
MGTDLLDDFSLEMTGKDVPALEEARGSIPQGTRINVTFLAGEDHATRLAAARAVRGLGFV
PVPHISARRLPSSAALEGFLAGLAEDGTADNVFVVGGDPARPEGPYEDALAVLHTGLLER
YGVRHIGISGYPEGHPAISGPALWSALTDKARAIGAGPFTGDVITQFGFDADPVLDWLAA
VRARGVDLPVRIGVPGPAGIRRLVGYATRFGVTTSASVARKYGFSLTNLLGTAGPDRFLH
ALGERYDPARHGVVKVHFYTFGGLRSTAEWVGGFRERTR
>A0A7X1FU25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium flavum|TrEMBL
MNRLAKAADHGCARTDVLNDYSLEITARDVDRLTRIAPGIPAGSQVAVTFLPGESPDARV
AAAAAVHRLGFTPLPHFSARRIASTEEFEGFLSALVSRAAVSRCFVVAGDPPAPDGPFHD
SLDLIRTGAFERAGIEMLGIGGHPEGHPHMTEEHCFEVLTAKCEEIRRRGMTPLIVTQFG
FNPDPVLRWLDDLRGRGIDAPVRIGIPGPAGIKTLLQFAGRCGVEASAAAMAKYGVSLGR
LLGTAGPDKLVDALAPALTPRLGDVRLHFYPFGGIERTVQWIETYRQRR
>A0A4Q4XPA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus sp. CRB-8-3|TrEMBL
MEKITDKIAALPADSNYFSLEFFPPKTAMGFANLRDRLDRMARALRPLFVNVTWGAGGST
ATKSLELAEICQRELSLTTCLHLTCTNMSRRMIDTALEDAKALGIRNILALRGDPPRAAE
YQDPNGEPEDAIDENFKWAIDLVRYIKKTHGDYFCIGVAAYPEGHADESHPQGQSLEHDL
PYLVEKTLAGADFIMTQLFFDTEAYDRFERTLREHPSGAFKTLPIIPGLMPIQSYQMIKR
TTKLSHAKIPDLISARLDAVKQDDEKVKSVGVDILSEIVERVKEIKSRTPGPKGFHFYTL
NLEKAVSFILERTNLIPPSEEEEEAVADVLASRVPKVEINGSTHEPPRPTEHRERRESIA
RSDVDASIHELPVPAQVRLRRQSTAEPRNRVIVSEGSPSHPEYEASQAEASILAEPINTR
ANTLAISEGEGTLGREATWDDFPNGRWGDARSPAYGEIDGYGPSLHVTNAQAITLWGYPK
KSEDINDLFVRHLKGELSAIPWSEEEFNAETATITSQLLELNSKGWWTVASQPAVNGLPS
SDPTFGWGPQQGFVFQKAFVEFFLPSAEWRILLEKLQSAEVQDTVSWYAANAAGDFASSD
LTGGLAGEAAKEPSTHAVTWGVFPGKEIVTPTIIEEVSFRAWSDEAFGIFAEWAKVYGKG
SESAALLEAVRADVWLVNIIHHDYMDTNALWNLLLK
>A0A0Z8EFD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARTIHQATHSLFKHYS
>A0A3D8I8K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter marmotae|TrEMBL
MFGIEFLPRSLHEDKTTIQLMREGALAYLKKQVDFILIPTNPRQVPSVDSLLASYALKQA
IDDISFIPTLSGAHYVGQSGVEQFYAQLLALRYANFKHIAIIGGERHNQESMTSKAMIHA
IRQELGEEIYIISGSGSLEDNIGKAKLQEKLQAGVNAIITQPLFEAKTAKAFLKTFRDIT
HTGGYEVQVFLGVFGIFHIKSALSINEANLGFKIPQSYIESMGLNQAKQSYERLWQDMQQ
VAKEYQASLYLSTPKHNDLRAYGG
>A0A0Y3LK23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYDHDPESLRVA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A660RW65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteria bacterium|TrEMBL
MEEKSRLQKVLEKGNFAVTAEIGPPRSADPEAVREKAKLLKGYVDAVNITDCQTAIVRMS
SLASAVIVMQEGLEPVMQMTCRDRNRIGIQSDLLGASALGIKNLLCLTGDHPKFGDHPQA
KPVFDLDSIQLLNLVKGLCEGKFLNGEEIKGKRPCFFRGAAENPFADPLEFRPIRLAKKI
KAGAQFIQTQIVYNIERFKKFMKMCEEQGLLDKVYILAGVTPPKSLGMLKYMKYNVPGLD
VPDELIKRMESAKDKKEEGINIAVEVIERIKEISGVRGVHIMAIGWESIVPEIVKKAKLY
PRPEIS
>A0A3R6XW41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM04-12AA|TrEMBL
MKIKDILAEGRPTLSFEVFPPKTADAYESVEKAASKIAQLKPDFMSVTYGAGGGTSDYTV
KIASTIKEEYGVTPLAHLTCVSSTREKVHHVLEELKAHKIENVLALRGDIPQDGKTPEVY
HYASELIREIKEAGDFCIGAACYPEGHPESSNKSVDMDYLKQKVDAGCDFVTTQMFFDNS
LLYSYLYRIREKGITIPVIAGIMPVTSGSQLKRIAQMSGSYMPARFLSLVDKYGDNPAAM
KQAGIAYATDQIIDLLANGIKGIHVYTMNKPDVAAQIQSNISELLK
>A0A1W9KBU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium ST_bin16|TrEMBL
MESQKKFPPAFSFELFPPQTPEGVEKLRLTRQQLARFNPKFFSVTFGAGGSTRERTLETV
LEIQAEGHVVAPHLSCIGSTQHNIRAILEKYYEAGIRHIVALRGDLPSGMAQAGEFRYAS
ELVAFIRQEYGSSFHIEAAAYPEYHPQARSAQADFDNFKRKIEMGASSAITQYFYNADAY
FHFVELCEAAGLNIPVVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLEGYGDDSESIHA
FGLDVVTGLCEQLLQAGAPGLHFYTLNSANLTSAIWQRLNLHAR
>A0A6N3GIC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi|TrEMBL
MLSIYAMIMVIKSEPPKAKEAAALCIWPNRQGDRKMKTTDIFAKKPVLSFEVFPPKRTNP
VETIYETLDSLRKLNPDFISVTYGAGGSENCKATTEIASRIKNEYGIESVAHLPCIGLKR
DDVISLLGGFKRAGIDNILALRGDIPEGGRPDGDFGHASDLISFIKENDEFKEFNVLAAC
YPEGHTESENILTDIRSLKTKVDAGADHLITQLFFDNDCFYRFRERASLAGIHVPVEAGI
MPVTNKKQIERMVSLCGVSLPSKFTAIMERYEHNPEAMRDAGIAYAVDQIVDLIARGVDG
IHLYTMNNPYVAAKIHEAVYRLLAA
>A0A7V7TX77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas leprariae|TrEMBL
MPQVPPAREKLRVSFEFFPPKTERMEEGLWAAIERLQPLSPDFVSVTYGAGGSTRERTHQ
TVKRILDESDLVPAAHLTCVDASRADIDAVIRQYRTTGVKHFVALRGDSQNGAGSPYAAH
AEGYQSSADLVAGLKAIDPTIEVSVSAYPEKHPESPDFATDIDLLKRKIDNGATRAITQF
FFDNDVFERFVERVRRAGIYVPIVPGIAPIHDFAKISRFAQGCGATVPNWLAARFEGLGN
DPQTHSHVAAAVCAEQVLDLADRGFRDFHFYTMNRADLVYSICHILGLRPKTAVAVVPAL
AAAE
>A0A5S9I8T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermus marinus|TrEMBL
MKVIEILEQATGPLISYEIIPPRRGGSLDEVLAVVEELMPFDPPFIDVTSHAAEVEYEQL
PDGTLKPRVKRKRPGTIGICAAIKSRFGVETVPHLLCRGFTREETEDALIELHYLGIQNV
MALRGDSPNYQKPIPPDRTVNEYAVDLVRQIVNMNRGIYLEPLEDAVPTDFCIGVAGYPE
KHFEAPNLIWDIMNLKRKIEAGAHYVTTQMFFDNRHYFRFVERCREVGITVPIIPGLKIL
TSKRHLQLLPSRFHIEIPEELVAEVEAAKPEHVPEIGIAWARRQAEELLEAGVPCIHFYI
MLRADYVREVVAYLRKIA
>A1JI18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTRIFE
GLDDDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A160P103|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces laurentii|TrEMBL
MSVTTTQAAPPAPTATGPTFSFEFFPPKTDKGERTLWDAIRRVEALAPDFVSVTYGAGGS
SRDRTIEVTKRIVTETTLRPVAHLTAVGHTVAELRAIIGAYADAGVRDVLVLRGDPPGDP
RGAWYPHPDGFTYAYELVELVRSLGDFRIGVAAFPEGHPRSPDPRSDLAHFVAKCKAGAD
YAITQMFFDPEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHR
LEAAKDDPATAYRVGVEHAARMGLRLLDEGAPGLHYITLNKSTAAREIHRTVLASRSFVH
V
>A0A1Z9MPG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. TMED205|TrEMBL
MTTALQRTLQAGNLAITAEVMPPRGGDASHTLAMADCLKGRVHAVNVTDGSRAVMRMSSL
AVCRLLLEKGLEPVLQLACRDRNRIALQGDLLGAHALGIHNLLCLTGDPVRAGDQADARP
VNEFESVKLLRQVSAFNSGEDPVQGTLADGATQLFAGCAADPQSRSWSGLQRRLQRKHDA
GARFVQTQMVMDAAALERFQRELAGPLQLPVLAGVFLLKSAKNARFINRVVPGACIPDDL
IARLEAAADPAMEGVAIAAEQVKRYLGIVQGVHLMAIKAEQRIPLILDQAGISISSLPG
>A0A5E7ZU27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp. EC-HK134|TrEMBL
MTTPRISFEFFPPKTLEASFRLWETIHALAPLDPRFVSVTYGAGGTTRELTREAVGTLHK
ATGLNVAAHLTCVDASRAETLEIADQFAAAGVSEIVALRGDPPKGSNGFVQHPDGFANSC
ELISALADTGKFTIRVGAYPEKHPEAADQRADIDWLKRKIDAGASEAITQFFFEAETFFR
FRDACAAAGINAPIIPGILPIENWVGARKFALSCGTQVPAWLDEAFDKAIRDNRHDLLAT
ALATELCSDLLDGGVEDLHFYTLNRPELTRDVCHALGVTPKVTLRDVA
>B6WAM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerococcus hydrogenalis DSM 7454|TrEMBL
MSEDELTRKLKILKEKNVNKILALRGDIPKFSYEKGDFDHASDLIRSIKEKGDFYVMAAA
YPEGHIDSPNLVEDIKNLRKKVDAGCDSLVTQLFFDNEDFYRFRDMCDLAGIDVPIQAGI
MPVINKKQIEKMISLNGIKLPKKFLKIMKRYEDDKIAMRDCGIAYAVDQIVDLISSGVEG
IHLYTMNNPYIAEKIHESIKNLIKL
>A0A4R5KGM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter terricola|TrEMBL
MTAQERAMIPTRIEIIPSEGIVEKVRASVPLSTPLTVTCLPHHGIARTVQVAVELSLLGY
TVLPHLTAHGLQDRAQLSGILRDCESAGITEVFAIGGDGPRNSGPYGSCLPMLEDIAELS
GGRISAGIAGYPEGHPSVTGLDLLEALLAKQHLATHVVTQMCFSVPKVLDYVSLLRREGV
ELPVWAGVAGAVPRTKLLSLATQIGVGTSLKFLTSKGALAKRLLSGDKYSPAPFVSELVA
QPGSISGIHLYSFNRLDRPSWSTAPDADDRATA
>A0A1G1MD75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium RBG_13_41_10|TrEMBL
MTFKEKLKSGKFLLTSEIGPPKGIETKQLLDDAELIRGRVDAINVTDLQSSVMRLGSLAV
CALLRREGFEPIFQITCRDRNRLALQSDVLSAAALGIENILVLTGDHPTLGDHPEAKPVF
DLDSVQLLQVVHNLQKGFDMKQNKLVGTPPRFCVGAVVNPGADPLEPQILKMEKKIEAGA
EFFQTQAVYDLKVFENFLNKTRHLKTTVLAGIVLLKSAGMARYMNKNVSGVFVPDNLIKE
MEETKDKVAQSVDIATRLIKDLRVMCQGIHIMPIGWDTVVPKVLDSCGF
>A0A851S3J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Certhia familiaris|TrEMBL
RFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDI
TGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDICVAGYP
KGHPEAESYEADLRHLKEKVFAGADFIITQLFFQPQTFLKFMKDCQAIGITCPIIPGIFP
IQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGL
HFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRT
QEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVFTCY
ITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGILTINSQPNINGKPSTDPIV
GWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNA
VTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYL
VNLVDNDFPLENCLWQVVEDTFELLN
>A0A3A6P592|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurivibrio sp|TrEMBL
MKITFADYIREHVILGDGAFGTYLYEKGIDFGRNIDLLNLKNPELIYSVHEEYIRAGSQL
IETNTFGANSFKLQKAGKEEQVGEINLAGARLAVKAAGHEVYVAGSVGPTGVEFPLISGE
ITQDDIKAAFAAQISALAEGGVDLLILETFTHLEEILLAIETARQVGSGLPIVAQMVYPS
QGKTTRGVDALTCARAALAAGAMVVGTNCGRGVDAMATAIGHLLPLAEEHVPLSAFPNAG
LPEVMGHRMVYPAQPSYMARRAAEMLRLGVRLIGGCCGTTPAHIHEFRKTLKLRHKKELR
SVTVAASPRESAAMPAAVQKSGRGGFLDSLQPRRLPVLVELDPPTHLDIDNVLAGARSLA
ASGVDAVTLGENPLSILRAGNIALAHRIREEAGIQVVMHQTCRDQNALGLQSHLMAAHIL
GIEAILAVTGDSASLTDQPGVSGVFDINSLGLIRMISQYNQGVNMAGRSVKLPTRFSIGA
AFSFNHANPTLQITRLERKAAQGAHFVMTQPLFTREEVEAMVEQTSHLNLVIFPGIFPLI
SARNADFLHNEVPGISIPAAIRQKLWSYEDVADQRKAAMEFTAKLVADLAPFVDGLYLIS
PLNKWEIAESFVKQIRQAGWQGSGRAAAR
>A0A7U3V2Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Abyssogena phaseoliformis symbiont OG214|TrEMBL
MKISFEFFPPRTNQGKEKLTRVRQSLSMISPEYFSTTFGAGGTTQDATLEAVLDIQKNDN
IPAAPHLSCIGSEKSNIIELLDKYKSANINRIIALRGDIPSGVCDIGDFHYANELVEFIR
SEYNDYFHIQVAAYPEMHPQAKNITSDLAHFVNKIKAGANGAITQYFYNADAYFRFRDDV
QKLGVDIPITPGIMSITNYTQLLNFSKMCGAQIPKWILERLKLYENDLESLGNFGFDVVS
NLCQTLKSQGVSSFHFYSMNRTEPSLKLAKNII
>A0A352N7A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaeria bacterium|TrEMBL
MSESKSTIQMEIDFQKQKRENVFRERLNKGSFYVLIEAITPEKKEDFAIAANRLKAVESS
LGKYDIIGTGLAITDKTAGWNTWNVADFANELSKEGRDRHVLYLSGRNATIKDVSDTIAR
CRSSGFQNLVPVTGDGYFPEGYKRRHKLNFVDSVCILNMLKSVDEDGFHFAGCTMNPFKY
TPSDIFPQYYKMVKKMKQGAEFIVTQSGWDMMKLQELRWYLEMRELHFPSIARFSLLTIE
LYEEIFSGKKPGMIISAELRKILLNEAKYGYAQFASAQWRRLQIYAAGAKFLGYSGIQIS
GIERQEHIATACSKVAEAMNEFKSFEEWRDGYLNYLSRADMTPYPYRFYMFNNLFTRAYP
ELATMKSADLPVGGKFEKLHYSLCRLFFSKVHRHAANEHLLAKKIFVGCRRCSTCRIPFT
QFVCPETCPKGLANGPCGGTHIDGTCEFGGKQCIHAKIFRLSAWQKELHSLEERYIKPLE
KI
>A0A4R4UIQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea deserti|TrEMBL
MALGRPSFFPERVPTVRDMLAGGGRSFSFEFFPPKTDEGERLLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERIAHDTTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVR
GDPPGDPTAEWVPHPEGVLYAEDLVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTDYFVR
KCRAGADYAITQMFFEADDYLRLRDRVAAQGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPRLAARFEAVKDDPAAVRRLGIEHGAELCQRLLDEGAPGIHFITFNRSSATREVFQRLS
GVRLSA
>A0A4R4U5R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea deserti|TrEMBL
MPFRGTEDAVLAHVPRTIPLTVTTTEAQGLAATVDLAQRLAGHGYTVAPHLAARQVRDEQ
QLADLVARLREAGIDGIFVIGGDAAQPAGGFPDALSFLEVLDANGHHFRRIGIGGYPEGH
GSIGQDMIDRAIELKARYATHVITQLCFDAETTASWARRVKERGVDLPIHVGLPGAVSRQ
KLIRISAGLGLGQSARFLKKQQSMLWRFLLPGGYSPDRLVERLAPRVSAPDGNLRGFHLF
TFNELEKTESWRRRMLAGAGQQA
>A0A1M3LX36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia sp. 71-9|TrEMBL
MSCTTARYSFELYPPRNERAAAALPATIDRLAAARPDFISVTYGANGSSRTSSLDVLRHI
LERTDVSPMAHLTCVGSSHEEANRLIREFLDAGVRRFLAVRGDPPEDAAPGEDGIGDIHS
SAELVQLIHRVQAERVPYGELPVPGLPAQAVLAHREHVQIAVAAFPNGHPASHSISQDID
ALLAKQAAGANLGITQLFFHAEDYLSFAQKAKDAGVAFPILPGIMPVTSPARLSRMLELS
GEDLPSDLAIQLEVEPTDEGRREIGIEWAARLGRRLLDGGAPGLHLYTFNQSEAVLSVLD
RIGALPAPDSTSSATEREPA
>A0A1J5M1E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseobacter sp. MedPE-SW|TrEMBL
MTSPEISFEFFPPQSLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRDLTRDAVKTLHG
SSGLNVAAHLTCVDASRAETLEIAENFAKVGVTEIVALRGDPPKGSGKFVPHPEGFANSV
ELIEALAATGKFTLRVGAYPDPHPEAPNAQADVDWLKRKLDAGADEALTQFFFEAETFLR
FRDACAQAGIDGDKLIPGILPIENWKGARNFAKRCGTVIPAWVDDAFEKATRDDREDLLA
TAICTELCSDLVDEGVKKLHFYTLNRPELTRDVCFALGLTPNVSLENVA
>A0A2M7LFZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium CG_4_10_14_3_um_filter_58_15|TrEMBL
MTKPTRPMGLVELEEAKRALDAPLFAGLSGDADVSFEFFPPKSDKMEKTLWDSVVTLEPL
SPRFVSVTYGAGGTTRERTHATVARIARETNIPAAAHLTCVGASKAEIAEVARSYWDAGV
RHIVALRGDPPAAGQAFEPHPQGYASAAELVKGLTDIAPFEISVAAYPETHPEADCPQSD
LDNLKRKLDAGASRAITQFFFTPEAFFRFRDAATAAGIDAELVPGILPVSNVAQTRKFAG
MCGAEIPSWMNDLFEGLDDHPSARQLIAATVAAELCRKLYAGGVRQFHFYTLNRAELSYA
ICHLLGKRPAGAQQEKAA
>A0A1V5RUB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin302|TrEMBL
MNIAEKLNNSDHPLFTFELLPPLKGRGIDAIYDTIDNLLEFNPSYINITSHAADIVYKNM
PDGSISKMVVRKRPGSVATAAAIKYKYNIEVVPHIICSGLNREEIENLLIDLNFLDINNI
FVLRGDPQKGSRIFIPKEDGHDHTTSLMQQVNMMNSAKYLDDSLKNPKATQFSMGVACYP
EKHIEAPNLTTDIQYLKEKVNLGAGYAVTQMFFDNQKYKDFVKSCRASGINIPIVPGIKP
IAALNDISLLPQIFNIDLPEDLVKEIQKCKTKEQVRELGVEWSIAQAKDLLAFGVPSLHF
YSLGESDNLKKICKAVF
>A0A1B7ZDQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter hydrothermalis|TrEMBL
MKVTDHITNAKGKTLFSFEIVPPVKGRNIQELYNNIDPLMEFNPPFIDVTTSREETIYVK
KEGLLDKKTTRMRPGTVGICASIQHKYNVDTVPHVICGGFTREETEYMLVDCHYLGIQNV
MALRGDARSEQKYFEATDGGHPFAIDLVKQIQDLNCGKYLHETIESEHCSDFCIGVAGYP
EKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVEAAKNMGITVPIIPGIKP
IAVKRHMQLLPQVFRIDLPQDLIEAVDGCATNKDVRKVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAEALF
>A0A2E1IGV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. MED850|TrEMBL
MVSALQRVLEAGAAAITAEVMPPRGGDASHTLAMATALKGRVHAINVTDGSRAVMRMSSL
AVCRLLLDAHLEPVLQLACRDRNRISLQADLLGAHALGIRNMLCLTGDPVRAGDQKDARP
VNEYESVKLLQQVRALNRGEDPVKGQLPDGPTQLFAGCAADPQSQSWSGLTRRLRRKCEA
GARFIQTQMVMDPAALERFQNELAGPMQLPVLAGVFLLKSAKNAQFINRVVPGACIPDDL
IQRLEDAKDPAMEGVAIAAEQVRRYLGVVQGVHLMAIKAEERVPLVLDQAGISSLPM
>A0A1I4L2I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas nitrosa|TrEMBL
MRSQKAFSPTFSFELFPPQTPEGIEKLRATRKQLAQFNPKFFSVTFGAGGSTRDRTFETV
SEILAEGHPVAPHLSCIGSTRENIFSILKKYQESGIRHIVVLRGDLPSGMAQPGEFRYAN
ELVTFVRKEFGDTFHMEVAAYPEYHPQARSAQEDFKNFKNKIEAGADSAITQFFYNADAY
FHFVDMCEAANLNVPIVPGIMPINKFSQLVRFADTCGAEVPRWIRKKLESYGDDIASIHA
FGLDVVTELCERLLKAGAPGLHFYTLNSAVLTTKIWQRLGL
>A0A8I1GC32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodomicrobium udaipurense|TrEMBL
MTEAGTQRRAHAPISVSFEFFPPKTDAMEASLWQAIRKLEPLAPEFVSVTYGAGGSTRER
THSTVSRILAETSLKPAAHLTCVAATKDEVDAVVRDYWDAGVRHIVALRGDPPAGAGTAY
AAHPGGYQSSADLVAGLKTIGDFEVSVSAYPEKHPESGSFDVDLDVLQAKVDAGATRAIT
QFFFDNDHYWRYLDRVRARGINIPIVPGQIPIHNFKQIAGFAARCGATMPASTAARFEGL
ADDPETTQLVAAAVAAEQVRDLVKGGVTEFHFYTLNRAPLVNAICHTLGIKPHAPAASAV
NA
>A0A0F9QCX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MRIMALSLKEKIEDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVIIYDI
QDESSRTNQARPFAFKQTVDPREYSHLLRDLSAQDVITYKSVAQRGVGEFKDWLSETKND
YDLQNVVLVGSPSSVGDIKLSLPDAYKAMAEQSDDFFLGGVTIAERHSSKRNEHERLIEK
TAQGCQFFISQAVYDAQATIELITSYARTCKAQGITPQRIILTFTPCGGEKTLEFMQWLG
ISVPEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDAS
IHLYRLLKAIMELNLAEKLIA
>X1M754|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
EMVRERELHKKVKILAGITPLKSVVIARYMKTKLSGVDVPDEIVERLRKATTREQVRKEG
IKIAVETVNSLKEIEGVAGIHIMAIEWEEVVPEICEASGLYPRFSLEELGRQ
>A0A0F9UBY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MVAENKVYSKLGALIAKGEFVLTGELEPGKTCDLSHTIQEAREMAPYIVAANVTDSPLAI
VTINSMAAAHIIQRETGLECVWQLTVRDCNKVGIAGQIMGAQALGLHNVLSLTGDHTALG
DCPESKPVFDLDSATLIKLVREMVDTGSINGHEIEHPPKFHVGCAANPNSDPMEAEILKI
GRKAEAGAEFIQTQVVYDIDMTADFLREIRKYNVPVFLGIFPMKSYGIAKGFDMFVPGVD
VPKDILARWKRVKTDVSDKKEQKETYDQLNYEFFKPFISELKSKGLLAGVHCMAVHYTRI
FSKLIDVIQS
>A0A0F8Y152|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSELKAGTNLERVLQAGHFAITAELGPPKSADVKVIKTKASYLKGRVDAVNITDNQTAIV
RMSSIAAGVLVSQEGLEPIIQITCRDRNRLAIQSDVLGAYALGLKNILCLTGDHQVFGNH
VASKNVFDMDSIQLIQALKDMRDEKRFICGDEIKNSKKAPVVEPRIYIGGAANPFGDPFE
LRVIRLAKKIKAGVDFIQTQCVYDMERFEAWMKQVCERGLHKKVKIMAGLTPLKSLGMAK
YMRNNVAGLSVPDYYLERLSKVEDKAAEGIKICVEQIKRLKEMEGVAGIHLMAIEWEKRV
PEIVQAAGLLPRP
>X0Y828|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKVTKLWSSRQKPTVSFELFPPKSPKGAEKLENTIDTLAGLKPDFVSVTFGAGGSTREGS
HQLVDKLKNEKMLEVVAYFAGYGLGPEDISAVLDDYQALGVENVLVVRGDLPREQENFKP
HPQSLPHASDLIAFIRPRYSFCLAAAGYPEGHIDCQSKD
>A0A859QNP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer mexicanus|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYSPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRLMRDNSKFLSGRKLTTAPHVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSVITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKRESQPGDALVAERLEHIREGIEENQQQMAEAAAH
HPH
>A0A7X7RUS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriaceae bacterium|TrEMBL
MNENRLDTLFENGTFIVTCEMIPGRGADEAHQSKELEVARELAIGGRVHAMSITDNPSGN
PALLADCFAEDLLAAGITPLVHMSCKDRNRSQLESQLWALERRGIHHVLAMTGDYPVTGF
SGRPRPVFDLDAVQLLQMITEMNKGLQTKAGKGLVTLKPTDFFPGAVASPFKWTEGELLP
QYYKLEKKIEAGARFIISQVGYDARKMDELIRYLRLRELNVPVIANIFILGAGVGKMMNA
GNFPGCFVSDELLAKLQEDAKSEDKGKSAYRLRAAKMIAIAKGLGYAGVHLGGINITAAD
IEQVLDAADAMQDNWQEYAREMSYGKKGGFYLFERDSATGLNLDVAASRVESRTDLKVQG
NYPLSRVAHKIAFTKGKGIYPAMSWVSHRGEAAKGMHRGHHIEHLGKVFMYGCRDCGDCG
LHATAYICPMSQCPKNQRNGPCGGSSDGWCEVYPGERYCIYYKAYHRLKRYEKETSLSEM
IWPPVNWDFFQTSAWSNYHHDRDNNALGLKMPKRPEL
>A0A0F9NIP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKITEHIAKAKGETLFSFEIIPPVKGHRIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKMTRMRPGTVGICASIKHKYDVDTVPHLLCGGFSKEETEYVLVDCHYLGIDNV
MALRGDAMKEEKYFKPTKGGHEYAIGLVEQLHNLNCGNYLHDTVESDHCADFCVGVAGYP
EKHLEAPSLKSDLKRLKEKVDAGAHYVVTQMFFDNQKYFEFVDAARNMGINVPIIPGIKP
IAVKRHLQLLPQVFRIDIPQDLIDAVDDCKDNKAVRQVGVEWCIEQSKELKEAGVPVLHY
YSMGKSDNIKAIAEKLF
>X1SG52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
IGVTLRIIPGIIPITNYQQLLRFCKTCGATIPQRVHEIFKPLDGDTEATYKAGVQFTVEQ
CNELLEGGAPGLHFYTLNKVDPTREILNKIKR
>A0A0F9XC18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKVTDHITNAKGKTLFSFEIVPPVKGRNIQELYKNIDPLMEFRPPFIDVTTSREETIYVK
KEGLLDKKTTRMRPGTVGICASIQHKYNVDTVPHVICGGFTREETEYMLVDCHYLGIQNV
MALRGDARSEQKYFEPTDGGHPFAINLVKQIQDLNCGKYLHESIESEHCSEFCIGVAGYP
EKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEAARNIGITVPIIPGIKP
IAVKRHMQLLPQVFRIDMPQDLIEAVDSCATNKDVRAVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAEALF
>A0A1G3QUL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium RBG_16_49_21|TrEMBL
MARSFRDILNSGKFVVTGEIGPPKGTNIDRMLRHIDLLKDKVDALNVTDHQSSVMRFPSI
GGALAIVERGGEAILQMTCRDRNRLALQAELLFAYTRGIKNVLCLTGDAVVVGDHKTAKG
VFDLDSSQLLRMVRLLESGKDMGGNDLDGAVDFCAGAIVTPEADPPGPQLIKFGKKIDAG
AEFFQTQAIYDLDNFRRFMELAKKFKVPVLAGIVLLTSAPMARFMNKNVPGIFVPQPLID
ELASAPKGEALKKGVEIAGRMIREIKQEKLCDGVHIMAIGKEETVPDILKAAGMP
>A0A1M6EGK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutispora thermophila DSM 19022|TrEMBL
MTIGNEMLPSHYISRQVHERRIKLKIKYLFRKKPVISLEIFPPKPESPIDTVLETVDALS
ALRPDFMSVTYGAAGSTKGPTVQIADIIKNKYGIEALAHVTCINSTKYEIDGILHQLKKS
NIENILALRGDKPKDEIYAARKHKEYEYASDLIAHIKSLGNFCIGAACYPEIHLEAESRE
ADLLNLKRKVDLGADFLITQLFLDNNFYYDFMEKISVMDISVPISVGIMPVINKKQIERI
TSLCGASIPAKFRRILDRYENNPEALKEAGIAYATEQIIDLLSSGVDGIHLYTMNKPEIA
IKILGQISNIRRHLKNLNYA
>A0A1R1CWA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL H8-0548|TrEMBL
MVRISLELVPRDSEGLRAELELVQAQFPSINTINIPDLTRFELRSWEATRLSKSFYKDSI
PHIRAMDFDADEPFVLAEYLDTHQISEILVITGDVPKNSSKPLYSTTCLDLIAKLKREHP
HLKIYSALDPYRNSVRKEYEYVQQKLNAGVDGFFTQPFFDLRLMTLYSEMMEGADIFWGV
SPVVSESSRRYWETRNHVVFPKDFQPTLEWNIEFSKQALAYTKQTNSNIYFMPIKVDLQA
YFDGVFSKVLV
>A0A1S1SUZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. LCM 4573|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIAXRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLSTVRTMRDEAKFLSGRKLTTPPHVFLGAA
INPFAPPYDFRPFRLGKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGFHEKCFILVGVG
PLASAKTARWIRSNVPGIHIPDSVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGIHV
MAYRQEEYVAEIVHESGVLKGRKPWKREANPTDALVAERLEQLREGREENQEQLADIAAH
KPH
>A0A1M7NLI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobacter sp. OV335|TrEMBL
MSRVPVSLEFFPPKTPEGVTKLAAVRQQLYALKPSFCSVTYGAGGSTQDGTLAAVQAILA
EGVEAASHFTCVGADRASVQAKLEQFKAAGIRRLVALRGDLPSGYGGFGEFRYASELIAF
IREATGQQFHIEVAAYPEMHPQAKSPQADLQAYVEKVKAGADAAITQFFFNADAYERFVE
DARRLGADIPVVPGIMPITNASGIIRFADSSGAEIPRWIRLRLQSFGDDTASIKAFGLDV
VTELCERLLRIGVPGLHIYTMNAATAPIEICRRLGLS
>A0A2H6AIR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR37|TrEMBL
MRFPDFFKCAKRPIISFEIFPPKTEKALENLLQVIPELIELSPDYITVTYGAMGSTREKT
LEIASLIKQHYNMETACHLTCVGASQREIDNILMRIYKAGIQNIVALRGDPPRGERDFSA
PADGYSYAYQLVEHIRRFEKTFIGQENFFGIAVAGYPEKHIEAPSLEEDILHLKRKVEAG
ADIVITQLFFNNEFYFNFVKKAKALNISVPIIPGLMPIVSVRQIKRITSMCGATIPPSLQ
EELEEAIDDDEKASEIGIRQCIKQARELLENGVPGLHFYVLNKSQHISRIMSAIKPYIYP
KS
>A0A5Q0NRU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. dk884|TrEMBL
MAEDRIASIAQLVRDGGRSFSFEFFPPKDEAGEEQLWRAISALEPYRPTFVSVTYGAGGS
SRDTTVRVTSRIARETTMTPMAHLTCVGHTRVELEGILDSYAEAGIHNVMALRGDPADGP
RAPWQATPGGLTYATELVELARARGDFTVGVAAFPEGHPTAESLDHDADVLVAKARAGAE
FAVTQMFFRASDYFALVDRVRARGIDIPVLPGIMPILNLNAIRRQGELIGCDVPADIVAR
ISAHDGDPAAVRAEGIALAAELCEELLAGGAPGLHFYTLNRSKATLEIFAALNMSV
>A0A4Q3YZC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger sp. IMCC34102|TrEMBL
MTRPALSFEFFPPKSLAGSFRLWDSVHALAPLGPEFVSVTYGAGGTTRQLTHEAVTTIDK
TTGLKVAAHLTCVDASRAETLEIADSYARAGITDIVALRGDAPKGDAAFTPHTDGFANSV
ELIEALAETGNFTLRVGAYPEKHPEAADADADVAYLKRKIDAGAAAAITQFFFEADTFFR
FRDRCVAAGIDAPIIPGVLPVENWKGASKFAKATGTSIPAEISQGFENAQTEADHDLLAT
ALASELCDDLLRGGVEHLHFYTLNKPDLTQNVCRALGIAPRPRLQEVA
>A0A3M6WTZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MLMNMDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGA
GGSTSAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGVRNILALRGDPP
RSDEYNDPNNPLSEQDDSNRDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQ
SVEHDLPSLVEKTAAGADFIMTQLFFDVEAYNDYEKRLRSHESGLFKTIPIIPGLMPVQS
YQILRRTTKLSHASLPPDVLNRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFH
FYTLNLEKVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVEDAKRNRQR
RKSSNRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPVNSRANTLAISEGQGSAGR
EATWDDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLQG
EIEAMPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSNDPIYGWGPKNGFVF
QKPFVELFLPSADWQRLKPILQADDQVTYYAGNAAGDFQSSDENSVNPVTWGTFAGKEII
TPTIIEGDSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGA
LWDALIAA
>A0A2E0ZE99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MDRKTFISRLRERPFLFDGAMGTLLHSRGVSMETSFDGINLSQPAIVADIHRAYIDAGAD
IIETNSFGANRYKLTEYGLQQQVHEINQAAVNIARRVIGSAFREVWLAGSVGPLGVRLAP
LGRVSLAEAADAFREQIEALLMANAAGSADGGIDLLVLETMSDLYEMETAVSVARELAPD
LPIVAQMTFTRDDRTLLGHSPNVVAQRLGALDVDAIGVNCSGGPAQVLRLLLIMRQIAPD
KLLAAAPNAGWPEQTQRGRVFYPATPDYFGQYTHALVEAGAVLVGGCCGTNEAHIAAMRH
ALDHPGPSPIPLPDIQIVTQAEKKTAVLDAPTQLAQNLVNGRYVVTIEMSPPKGVATQRL
IEGAHMLKEAGANLLNLADSPLARMRMSAWAAAHLVQKSVGLETVLHFPTRGRNLLRIQG
DLLAAYAMGVRNLFVTMGDPTRIGDYPEAMDSYDIVPTGLIHLIKQQFNSGLDKAGNSID
QPTNFTVGCALNLTPADPQREMKLLRRKMRNGADFALTQPVFDPAAAKAFVDLYESTYEE
KMLPLIVGVKPLYNGRNAEFLHYEVPGMSIPEPLRQRMAEASDPQTEGVAIAQEILAQLR
PFTQGVYFMPAFGRYDLVANVMDVLGGD
>A0A7Z9PZW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MSNLYAQSTEPIFSCEFFPPRSEEAQASLERELPKLMSLPFQLATCTNGACGSDRSGTAE
TLRKIGQEGAVTLAAHLCCRGSTPDELKSTVNHLKDAGARWIVALRGDRESPRGFQHADQ
LVSLLNEEYPELGVVVAGYPETHPESETAQSDLIFLKQKIDSGAHAVYTQFFFENSVFLR
YRDRCAKIGIDTPIIPGILPIKSLRQVERLVERCGANLTDDLKKHLSEAEDEAEAGFQFT
LNLVRGLLEEGVAGLHFYALNEATFVTRLFEELGLVRDSAHSCLA
>A0A7C9W3W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentzea alba|TrEMBL
MTSVVERLQGESPKFSVEFLPPRDAEDEKILWKAVRELEGLDPAFVSITYGAGGSRRDRT
IRATGRIAQETTLLPVAHLTAVDHSVAELRNVIGWYAAIGVRNVLALRGDPPGDPMGEWV
AHPDGLNYADELVRLVRELGDFCVGVAAFPYGHPRSADLDTDLKFLLRKLNAGADYAVAQ
LFHAPEPFLRMRDRVAAAGCSAAILPGIMPMLSPRGLSKIVELSGADLPLDVSRRLEPYA
DDVAGFRATGIDIATEMCQRLLDEGVPALHFYTMNRSKATKEVLGRLGLVARA
>A0A7S7C0K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. WG16|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A3D4NBN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MPGFTPARRWQQAYYPFKNRTASQKIEEALERTIKGALFGCRMCGNCLLQETALICPMEC
PKGLRNGPCGGSTPEHCYVDETRPCVWYKIYERAEKYGRLDVLMEVLPPLDWDKVGTSPQ
PDGWNNLRRHGGIKAISRYLRSTPEIRKQKWEHFFKEIRQPDWWQGDALPHPAPLHVPVS
HLEQLLSEGKFAITAEIAPPLSASPDDLVKKILMLKDCVDAVNFTDNPSSTPRMSSLACS
LIALQNGVEPVLQIAARDRTRMGLQGEVLGASALGIRNILCLTGDHPRLGPGPNGRMDIW
DIDAIQAMWIIRRMRDEAHFLDCREIKCAPQVFIGAAGSPYASTLLIQSMREEKKVNAGA
QFMQTNLVFDYDGFQQYLEALDRRDVTRRVPILAGISPIRSIKAAYAMRQVPGVKIPEAI
IQRMEASADPKEESVQIMLELIDKVKALPGVRGIHFMAVGWESIVPRLIKDSGLR
>A0A6I6GB02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phnomibacter ginsenosidimutans|TrEMBL
MKVTEHIQKAAGNTLVSFEVLPPLKGKTIQTLYDHLDPLMEFQPPWINVTYHRAETMFKK
KADGSFDKVEVRKRPGTVGICAALRNHYNVDAVPHLICGGFSKQETENALIDLHFLGIDN
VLVLRGDAEKNEPSFVPHPDGHRHATDLLKQVVDLNHGLYLEDDIQNGGKTNFCIGVAGY
PEKHFEAPNLEIDLQYLKEKVDGGADYIMTQMFFDNQKFFEFEKACRAAGINVPIIPGLK
PLTTKKQLTVLPRIFHVDLPTELSLEVMKCKSDAEVEQVGTEWLIQQSKELKAHGVPVLH
YYTLGKPKVIWNVVKAIV
>A0A6H2VH39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A5J6GVB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces prasinus|TrEMBL
MALGTASVRTDHARTVRDMLAAGKTTYSFEFSAPRTPKGQRNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVHETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPTADWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSAEWDTDVAHFVD
KCRAGADYAITQMFFHPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPRLSNASF
PDALKERILAAADDPATVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A6P2ANB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHIRDIFERHSTTFSFEFFPPKTDKAWDALFKRISDFETLAPSFVSVTYGAGGSTRERTH
DLVVRLKRETKLDPIPHLTTVLQKRAEIDRILERYAEAGISNILALKGDPPSSVDDYDPD
ADEFPHAIDVVRHIRKFNESGKHSDSRGFGIGVAGFPEGHPATPNTLMDIEYLKQKVDAG
ADYICTQMFFDNRAFYDYCERCELHGINVPILAGLMPITSLKGMKRMGDLSGGTNFPAPL
QRAIYRCQDDPDAVQRVGIHWATEQARDLIDNGVRGIHFYTLNRSDATSEIYRTLGVKDS
AALR
>A0A7C7TGV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lambdaproteobacteria bacterium|TrEMBL
MEEFRVIAAALSVPDSFLHEAVAPCTDWSLEILPKHAEAVRDLPDYIREIYVTVIPETPW
AEVVAAVRTVHELGRSPIPHITARSIPDKNALEQLLLQFKEFGVERALLIGGGIPEPAGE
FTSVLELLQSGLFEQHGLRDLDLAGHPEGNPDDPHAEQSLLDKLTWGRERGYRFRIVTQW
CFDADAVNKWIARLRELGVTEPIHIGVPGPATMKTLMRFASLCGVKASATVLRKQGLHLT
KLLFVNKPDKLVDALRGHDQLHLFPFGGMDKASVWLEAWHRTHA
>A0A7V7I8F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. BB56-3|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A847FI03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
GAYALGCRNLLCLTGDHQTFGNHPQSKNVHDLDSISLLQAVRDMRDQKVFQCGEKIKGQE
PRFFLGAAANPFADPFEFRPYRLAKKAAAGADFIQTQIIFNVPKFQEFMRRVVDLGAHEK
TYILAGVAPIKSLGGAKYMATKVPGMEVDPEYITRMENATKGLPTIAEIKAMEPKEAAEA
RKARQQAAETAGIGICVEIINECKKIEGVAGVHIMAIEWEQAVDSIVSQTQIGPKYDPSR
QAA
>A0A2H1GUP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymoseptoria tritici ST99CH_1E4|TrEMBL
MDKITDKIAALPPNANYFSLEFFPPKTQQGFSNLNARLSRMAHSLRPLFVNVTWGAGGST
SAKSLALAEVTQRELGLTTCLHLTCTNMSRKLIDEALEQAKVLGVRNILALRGDPPRSDE
YRDNSLPNADEDDSNKDFTWAEDLVRYIRKQYGDYFCVGVAGYPEGHSDQSCPEHQSMEH
DLPFLVEKMKAGADFIMTQLFYDVEAYERFERRLREHESGAFKTVPLIPGLMPVQSYQIL
RRTTKLSHAALPEEMLKRLHAVKGDDEAVKRVGVDVLSEMVEGMKSRKGNGPQGFHFYTL
NLEKVVAQIVERTGLIPPEEKKDENAVADDEVGDFVLVDKDVKQKQRRRKSSMANSQSRN
RVIVARTRASSNSSTRTSAAHEVPDDEAGIPREKINSRSNTLAISEGDGALGREATWDDF
PNGRFGDARSPAYGEIDGYGVSLHVSVPDAKRLWGEPKTIEDISTSFRRHLSGEIEAIPW
SEEPLQNETLTIKDQLQSLINRGWWTVASQPAVNGVRSTDPVHGWGPKNGFVFQKPFVEF
FIPASDWSALQGKLVEHPQITYFAGNANGDFVSSGEDTVNPVTWGTFAGKEIITPTIIEA
VSFKAWCEEAFGIWAEWQRVYKPGSESSRLLERIRKEYWLVSVIHHGFLEEGALWKDLLE
A
>A0A518WKP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. HM134|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTAQGERLLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVR
GDPPGDPGGEWIRHPEGVDYAEDLVRLVREAGDFSVGVAAFPYKHPRSADVASDTAHFVR
KCRAGAAFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQLGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQASEMCARLLDEGVPGIHFITLNRSPATREVWRSLR
ADARV
>A0A1M7DAY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. OK091|TrEMBL
MPAISFEFFPPKTDEQRSQLDRAAQVLKAYQPEYASVTFGAGGSTLSYTGETVARLHAQH
GLNVAPHLSCVGGTRAELGALLDDYRAAGYRRIVALRGDMPSGMATAGDFRYAAELVGFI
REHCGDHFHIEVAAYPETHPQADDALRDLQHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VRKLGVNVPIVPGIMPIANYSQLKRFSDMCGAEIPRWIAKRMQAHGDDAESVRALGAEVV
AQLCRRLLEGGAPGLHFYTLNRAKATQSVLQQLA
>A0A1H0K060|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nakamurella panacisegetis|TrEMBL
MADGRGGFVLFALTPPREAASPQRVAEIAEATIKRLSSVELDGVILYDITDESDRNPDER
PFPFLPTRDPATYLQEHFLTWPTPAIVYRAVGKYSEDQLRSWLSAQDTDRVLSVFVGASS
RGRETAISLARAYSLRNEVRPDLVLGGVAIPERHMRRRDEHLRLIAKQEAGCSFFVTQVI
FDANAAKNMISDYRHECRARGLPLVPIVFTFSVVGSLTTLEFLRWLGVEVPHWVERDLTD
SATPLQISHDHALAVAADLVNYCRRMDVPFGINVESVSARRDEIEMSVKLAGQIAAVCGE
NVRPFDGA
>A0A1T5EED8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Soonwooa buanensis|TrEMBL
MKVTEHIEKANGKTLFSFEILPPLKGQNIKSIFDGIDPLMEFNPSFIDVTYHREEYEYIE
RQDGLLEKRVVRKRPGTVGICAAIQNKYKVDAVPHILCGGFSREDTENFLIDLDFLGIEN
VVALRGDAVKSEIYFKPEKNGHANASDLVKQIQGLNSGDYLDESLENSCPTTFCIGVAGY
PEKHMEAASLSQDLQYLKKKVEAGADYIVTQMFFDNEKYFEFVDKCREEGINVPIIPGLK
PLVTKSQLSMIPHRFKVDIPNDLVIEVAKSKDNKAVKEIGIEWCIQQSKELLERGAPVLH
YYTMGKSEITKRIASSVF
>A0A401G0V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfonema ishimotonii|TrEMBL
MKSGSNLEKVLKAGHFAFTGELGPPRSANVEAVREKARFLKGMVDSVNITDNQTAMVRMA
SWAASLIAIEEGLEPNYQMVCRDRNRLAMQADILGASAHGIRNMLCLSGDHQQFGDHPYA
KGVFDIDSTQLIAMTKKMRDESKFLGGADIDTPPKIFIGAAANPFAEPFEWRVHRLAKKI
EAGADFIQTQCIYNMKKMREWVRLANEMGLTEKVAILAGVTPMKSLGMARYMKKSVPGMD
VPDEVINRLKGAGKGKYAKEGIKMACEQIEEFKEMKGVAGVHLMAIEWEHKVPEIAELAG
VLPRPTFDDEPETTEAAE
>A5TSW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. polymorphum ATCC 10953|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEIGD
FNYAKDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A1E4ZX86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MEQRNVDLSPAELLPILPGHSSPGRFERVLRAGKFAVTTELAPPDSADPAQVYERASIFD
GYVDAINATDGSGAHCHMSSIAVCGLLTRAGYSPIMQISCRDRNRIAIQGEILGASAMGV
SNILCLTGDGVQAGDHPEAKPVFDLDCMSLLEIGKQMRDGGTFQSGRKLDHSPPIFLGAA
ANPFAPPHDWRPLRLAKKIAAGAQYVQTQYCYDIALLQNYMSRVRELGLHEQVYTLVGVG
PLASARTASWIRTNVPGVHIPDSVIDRLSGAKNQRAEGINLCIELIQQIREIEGVNGCHI
MAYRQEHAVPEIVERSGILQDRNRRKRTISN
>A0A259JE01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium 34-67-9|TrEMBL
MAQALPISFEFFPPKTPEGAVKLRAVRQQLYAQRPEFCSVTYGAGGSTQEGTFATVAEIL
AEGVPAAAHFSCIGATRASVREQLRQLQGMGVRRLVALRGDLPSGYGSGGEFQYASDLVA
FIRAEFGVAFQIEVAAYPEVHPQARSPQADLQALLTKVRAGADSAITQYFFNTDAYFRFV
DEAHALGIEIPIVPGIMPITNSSQLLRFSDACGAEVPRWIRLRLLGYGDDVASIQAFGRE
VVGDLCEQLQLAGVPGLHFYTMNQSAPTLALCARLRQ
>E0N9I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis ATCC 13091|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFHAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A4Z0I2C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E5028|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRSIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A357KVA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHIRDILKLRQTTFSFEFFPPKTDKAAGELFEAVRELEPLHPSWVSVTYGAGGGTRTRTN
DLVVKIKQTTALDPMPHLTCIYHTEAEIYDILEKYAGAGVSNILALGGDPPRDMPNYDRS
RDAFRYASQLVRFIREFRERHAGKSIGDPRGFGIGVAGFPEGHPGTPNRLDEIDLLKAKI
DEGADFVITQLFFENRDFYDFRERCEIAGITAPIIAGVMPITSLSGMKAIAGLALGARIP
ARLLRAVDRCKGNAEAIRRVGVHWATEQCRDLLDHQVRGIHFYTLNRSTATRDIYANLGF
EDSLSVA
>A0A377J5R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter canis|TrEMBL
MSATLDSKITAAFSKLESSGDFVSFELTPLVGAQVLAQDTLDELRDCTLFDSFVCTDSPL
ARFKPSSVLSSIALQNALQTPLICTLSMRDRNTAALCGEILGANAFGLRAFLSLTGDPTK
LGNTDSKAVFEDNSTRLNAIINALNAGLDLTGNTLKSTPNRIYNCNVINSYAINTKTIES
KMIKKIKSTKVDSSCALSAFFSQPVYSIESAHTLLDSLESANRTLGTRVSLVLGFFPVVS
YKSAVFLRDKLPGVFIPESWILRLEKAHKSHDPKAEKQKVGLDLSRELFYSLRKIHNKFH
FMTNNNLPLARQILL
>A0A3N4UQP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pacificibacter maritimus|TrEMBL
MTKTPNISFEFFPPKNMAATFGLFETVNALHDLNPGFVSVTYGAGGTTRTLTHEAVELLH
KKFGLNVAAHLTCVDATREETLAIADAYYDAGVTELVALRGDAPQGAGGFKPHPDGFANS
IELIEALAQTGKFKLRVGAYPDPHPEAADENADVQFLKRKFDAGADSAITQFFFDPDTFF
RFRDRAEAAGITGKILPGILPIGSWNGVKKFAQSCGTPVPTHLDDLYAKAGENAEQLSID
LATEMCEKLIAGGVEDLHFYTLNKPHLSKAVCANLGINPA
>A0A6J4FJK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum sp. UT-4|TrEMBL
MSRQLPIAAAARPVAVSFEFFPPKTEKMQATLWDCIKRLEPLAPSFVSVTYGAGGTTRER
THETVVRIARETGLKAAAHLTCVGHAKGEVDDIARRYWDEGVRHIVALRGDAPEGSGPYV
PTPGGYAYAADLVAGLKRIADFEISVAAYPEVHPDAPDAAFDLDNLKRKVDAGATRAITQ
YFFDVDVYRRFIDRARAAGITVPIVPGILPVTNFAQVQKFSAACGATVPGWMAKLFEGLD
DDPETRRLVAATVAAEQCRALAADGVDQFHFYTLNRADLAYAISHILGVRPARSA
>A0A0C3LVM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKIIYETLGELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKNIIGE
YNYAFELIEKIKANNKFGVSGACYPEGHIECESLEQDIRELKRKVDAGAEHLISQLFFDN
NVFYEFLNKAQQKNINVPIQAGIMPVVNKKQIERIVEISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINRDVAV
>A0A7X3S5L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0666_bin_27|TrEMBL
MHIAEVFRQSQPAISFEFFPPKSEAASESLFHTIQKLIPLKPAYVSVTYGAGGSTRELTH
DLVVKLHNETNLTIVSHLTCVKSRRDEIFKILQRYDEHGIQNIMALRGDPPTQEPWDPAE
QDFHHAVELVAFIKEHFPHMGIGVAGFPEGHPDTPNRLQEIEHLKAKIDAGADYICTQLF
FDNRDFYDFCERCRLAGIRVPIIAGIMPITSLKGMKRMAELALGARFPGRLLRALASAKD
DAQAEKIGTHWATEQVLDLLDNKVLGVHLYTLNRSRASLQIYETLGLQRVDMPME
>A0A848HSN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. TB-6|TrEMBL
MTLSFPSVEEARRALDAPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIQTLTPLAPKFV
SVTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKAEIDEVVDAYWEAGVRHIVA
LRGDPPEAGTKFEPHPDGYKGAAELVEGLVKRHPFEISVAAYPETHPDALSAQSDIDNLK
RKLDAGATRAITQFFFEPDTFFRFRDTVAAAGIDAEIIPGIMPVSNFAAVQRMSAMCNTD
VPGWMGKLFEGLDDLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPATLEKTA
>A0A1G9UBI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospira pectinoschiza|TrEMBL
MNLKAFLKDNRLMIDGAFGTYYNNLFDTNELPEFANITNKDRVINIHKEYIEAGAKLIRT
NTFACNSISLDTSIDRVKDYIRAAISNARTAIKLAMQEANKEDELSDSDTFLAASIGPIP
FSDLMDREMLTKEYLEIVSAFIEEGVEIFDFETFDSLDYIMEAIKLASKQGEVLVSFSVN
QYGYSNAGLSARHLLEDANNCDEIFATGFNCGVGPSHMEAIIKKLSYMITKPLMAVPNVG
YPSNVSGRMVFLNQNVDYFKERIDNLLDCGVDIIGGCCGTNPKHIKAIAKNFDFKGKVRN
IDNEVKETRKEAITDAAFYNKPNQASGKLIAVELAPPLNGDDEKLISSALYLKNKGVDVL
TFPDSPSGRTRADSILVANKVNIETGMCVMPHICCRDKNAIAIRSQLLGAYVNDIKNFLV
ITGDPIPSIVRSSVKSVFNFDSVGLMNIIKDMNYDQFNQSQMVFGGAINQGRSNFKVELN
RVLKKLEAGATFFFTQPIFSKEDIDRLRTIKEAVGDRAKILAGIMPLVSLKNASFMKNEM
AGINVTDEILSMYREDMTKEEGEEVGIKVAKSVISQTKDFIDGYYFSFPFNRVYLLDRIV
SDKL
>A0A367AHW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. TBT05-19|TrEMBL
MTRTVRELLATEGPTWSFEFFPAKSAEGEAQLWTALRELERLRPSFVSVTYGAGGSTREG
TLAVTERIAAETTMTPLAHLTAVDHTIAELRHIVSRLVAAGVRNVLALRGDPPGADPQAD
WVAHPEGLQYAAELVELIRSMGDFSVGVAAFPELHPRSPDPDSDVQQFVAKCRAGADFAI
TQMFFRAEDYLRLRDRVAAHGCEVPILAGVMPVTDVRQIARIVQLSGQAFPEDLMERFTA
LDGDRPEDKAAVRDLGVEVATDLCRTLLDEGVPGIHFITMNRSTATREVFTNLVDRSGDA
VTP
>A0A0M0AEC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MNIKNLFRDKKVVFSFEIFPPKTTSSIQTIYNTLDDLKGLNPDYISVTYGAGGSVKNNKT
IELTSLIKNKYGIEAVSHLTCISSTKSDIEYYLREFEKNNIENILALRGDIPIGSKITGE
LNHANELIKHISDNGQFNIAAACYPEGHIEHKGSYREIESMKRKEEAGASYFISQLFFDN
NLYYNFQDEVRAANINLPIEAGIMPVTNKRQIERILSLSGASLPDKFKRIMERYEHNPEA
LRDAGIAYAVEQIVDLISTGVDGIHLYVMNNPYVAKRISQSIENILLTVNQNQFV
>A0A3D5XWC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MGNTKHTKEQIRERIQQKKLLFDGAFGTYYGGKYDTKQLPELANLEAPERVKEIHTEYLE
AGAQILRTNTFAANSFCMDMSKEQIEETLRSGVRLAREAVAAWRARTGETKEVYIAGDIG
QIPGDALAQKDTLCREYEEICRIFLEEGVDFFVFETFSEMEELLPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGAIKEIDAVGFNCGVGPSHMYRILQTLYKPADKFLTALP
NAGYPQMVTGRMIFTGDNREYFVDRMQQMIALGVDMAGGCCGTTPEYIADLAGKLDFTQY
PQAKANAEPEKKQAGTEDHSFYHNKEAEGRKKLIAVELAPPAGIDDEKLMDAAHLLQRSG
VDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGIH
NFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFAQAPVSYGGAINQGRRNLE
VEIGRVKKKMAAGATFFLTQPISTKESADRVRRIKEETGARILCGIMPFVSLKNATFMKN
EMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVIAMTEDFADGYYFSFPFNRVTMLEK
ILD
>A0A010RN86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum fioriniae PJ7|TrEMBL
MHIKAMLDESRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREQEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGATF
IVTQMFYDGDNFVRWVGKVRERGITVPIIPGIMPIATYSSFLRRAKHMNCKVPEEWMAAL
EPIKNDDVAVREVGKGLVAEMCRKIVAAGIHHLHFYTMNLAQATRMVLEELEWMPTSDRP
VKHALPWKQSLAHGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSVKDIANIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSTHPVHGWGPANGYVYQKAYLELLVHPDVYHEIVARVEKNP
DMTYYATTKNGNLRYNASNDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGIDW
AHCFEAGSPSRTLVERIMNEWYLINIVNNDFHQKTALFDLLEGLEVKEYSDISDEPQTNG
AVKEQQTNGSAPAAAVAAN
>A0A4R3Z9S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella sp. BIGb0138|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPRFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A412LBQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus bromii|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGIESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKD
FAYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A2N0UXA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus bromii|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGVESVAHLTCINSTKADIDRNIALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A417DX69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM40-10AC|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A3C0NZK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MALRGDIPEGGRIAFDYTYAGELIRDIRDLTGNDFCIGGACYPEVHPDSATKDEDIDHLK
LKVESGCDFLTTQMFFDNSILYNFLYRIRKKGIEIPVLAGIMPITNAKQVARTVAMSGTQ
LPQRFISMVDRFGHNPEAMKQAGIIYATEQIVDLISNDVNHIHVYTMNKPEIAEGILNNI
SELIK
>A0A3D4LPL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIADICKKKKSLSFEIFPPKRTEDLENIDETLSVLCECDPDFISVTFGAGGSSNCNRTI
ELAKKIKNEYHVEPVVHLTCLHYNKSEIDEFARILTQEGIQNVLALRGDRNPDIPEKDDF
KHASDLIRYLKPKSDFCFLGACYPECHPESDGKISEMKHLKAKVDAGAEVLLSQLFFDNE
QFFRFVEDCRIAGIGVPVIPGIMPVINARQIKRMVTMCGASFPERFQRIIHKYEDNKEAL
FDAGMSYALSQIIDLLVSDIDGIHLYTMNNPLVARKICDGIRHII
>H8G798|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora azurea NA-128|TrEMBL
MRTVVDRLTSGRRPTFSVEFFPPRDEADEAILWRSIRELEPLDPAYVSITYGAGGTSREG
TIRNIARVATDTTLVPMAHLTAVDHSVAELRHVIGHFAAVGVRNILALRGDPPGNPMGEW
VAHPRGLTYAEELVRLVRELGDFCVGVSAFPYGHPRSTDLETDTHYLVRKLDAGADFAIA
QLFFEADDFLRLRDRVAAAGSDALMLPGIMPLTTPRTWRKTIELSGATPPRWLVERLEPL
SDDPKAFRAEGLDVITELCEQLLAEGVPELHFYTFNRSKATRELVDRLGLRAPRTQAAVT
GA
>Q98L03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)|TrEMBL
MSARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A1I4CQD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas stagni DSM 19981|TrEMBL
MDQAYPGTLQRWLTGPRVAGLPVPSEMPPPKLSFEFFPPKNEALEQSLWAAIRRLEPLGP
RFVSVTYGAGGTTRTRTHETVARLAKETSLTPAAHLTCVGATQAEVDEVARGYLEAGVRH
IVALRGDPPAGASQYTPHPGGYAQAEDLVRGLRRIGDFDISVGAYPETHPAATSADADLD
FLKRKIDAGATRAITQYFFDTDIYLRFIDRCAAAGITVPIVPGILPVSNFSQVKKFSAMC
GASVPAWMGKLFEGLDEDAETRRMVSAAIAAEQVRLLQANGVDEFHFYTLNRADLTYAIA
HLLGARPKAA
>A0A7X1I1T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces mexicanus|TrEMBL
MALGTASTRSDHAPTVRDMLATGKRTYSFEFYAPRTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHITAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPQGLTYAAELVELIKTSGDFCVGVAAFPAMHPRSEDWDTDVRHFVA
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCDTPIIPEVMPIASVKTLMRVPHLTNAAF
PPAVKERILAAKDDPAAVRSIGIDFATEFCARLLAEDVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>D6E777|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonibacter pamelaeae 7-10-1-b|TrEMBL
MTPMRSVADIYAAARAAGRQPVSFEIFPPKGDLTLETAHEVAAELADLLPDFVSVTYSAG
GSGNRQATADVAAMIHDDFDIPTVAHLTCLGATEESISRAIDDLKRKGIASVLALRGDRT
ADAPAAEGPFRFAKDLVMRLADEGFCVGAAAYPEGHIECTDFRASVAHLKQKQDAGACFF
VTQLFFDNSYYYRFREAADAAGIAVPIACGVMPFLGKAQIQRMVFMCGASLPSPIIKLLA
KYEDDPGSLRAAGIEYACAQLTDLQQHGADGLHVYTMNQPDIARACAGALRASCHGAPYL
TWECAEGGLLHSPNALVFGHHLQDGTMFSKLGGFIDVAYLDEHTPIQIQTPTEKASLTVL
AVDRVNANRETARLEFDTALDHATWLASVTAASDRNLSSAGFDFDSVENVVTLCTCSYST
WGNERTLVYCAIEMAD
>A0A7R9UE39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pinguiococcus pyrenoidosus|TrEMBL
MAQKLTDLFQQQKANEPWVSVEFYPPRTPEGVENLKGRIERMQKGLNPVFGDITWGAGGS
TSELTLELSKAMQDDYGLVTNMHLTCTNMPAEAVHTALEEAKAAGIRNIVALRGDPPNGL
DG
>A0A6L6UEH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella endarachnes|TrEMBL
MKVTDHIKNANGKTLFSFEIIPPKKGNSIQQLYNNIDPLMEFNPPFIDVTTSREEYLYIE
KDGLLDRKITRMRPGTVGICAAISHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIHNV
MALRGDAMKHEQYFKACEGGHQFAKELVGQIQNLNKGQYLHDVVEVDDKSDFCIGVAGYP
EKHLEAPSLKTDLKRLKEKIDAGADYVVTQMFFDNQKYFEFVEAAKAEGINVPIIPGIKP
LAVKRHLQLLPQVFKIDLPEDLIDAVETCKNNQQVRQVGVEWAIQQSKELQDAGVPVLHY
YSMGKSDNVKAIASELF
>W3V8L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus khanii NC19|TrEMBL
MFRRLNKSNWQIIRQEIIPLVNEVQGMSFFHANQREALNQNLAELEGQIRVSFEFFPPRT
AEMEKTLWKSIGRLSTLKPKFVSVTYGANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDA
SRDELCEIARDYWNNGIRHIVALRGDLPDNSEKPKMYGADLVELLKKEADFDISVAAYPE
VHPEAKNSQADLICLKRKIDAGANRAITQFFFDVESYLRFRDRCVAAGIEVEIVPGILPV
SNFRQLKRFATMTNVRIPSWMTRMFEGLDDDPESSNLVGASIAMDMVKILSREGVKDFHF
YTLNRAELSYAICHTLGVRP
>A0A1B8S1S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leisingera sp. JC1|TrEMBL
MDHTMSQPYSAPPEGHVSHSRLERVLRSGRFAITAELNPPDSADPADVYEAARPLGEVAD
AINATDASGANCHMSSIGISALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAAMGVSNVL
CLTGDGVGVGDQPGAKPVFDFDSLSLLRTIKTMRDERKFLSGRTIKNPPQLFLGAAENPC
IPPYDWRPERLAKKVEAGAEYIQTNYIYDVPLFEKFMARVRDLGLDKKVYILAGVGPLAS
ARAARWMRSNVPGIHVPDAVIDRMEKAEKPGQEGKKICVELIQQMREIAGVSGVHVMAYR
KEHEVSEIIRESGVLASRKR
>A0A2E0D795|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTEHIKQSENTLFSFEILPPLKGKSIDSIYNSLDPIMEFNPAFIDVTYHREEYVYKKR
KDGLLERISVRKRPGTVGICAAIMNKYQVDTVPHIICGGFNKEETENALIDLDFLGIDNV
LVLRGDPIKSETYFSAEEGGHSYASELLSQVDNMNKGIYLDEDLKSSVPTNFCIGVAGYP
EKHFEAANMRSDIHFLKKKLEAGADYIVTQMFFDNQKYFDFVKLCRKHDINIPIIPGLKP
ISTQKQLSLLPQRFHLNLPNELVDEVLKCKNNDDVRQVGVEWATQQTKELLDFGVPCIHY
YTMGKSENVQKIVGSFL
>A0A2T7G4G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagivirga sediminicola|TrEMBL
MNAPNISFEFFPPKTLEASFRLWDTVHTLAPLQPRFVSVTYGAGGTTRTLTREAVSALHG
SAGLNVAAHLTCVNATREETLAIADEFHAAGVREIVALRGDAPKGSGGFKPHPGGFNDSC
ELIAALKERGDFTLRVGAYPERHPDAADDNADVEWLKRKFDAGADEAITQFFFSADTFLR
FRDRCAAAGIDKPVIPGIFPIENWDGARRFAQSCGATVPDWLNAAFATAERDERSDLLAI
AHATELCSKLMDEGVEDLHFYTLNRPELTRDICHALGVAPKVQLRDVA
>A0A385MRH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. RKMC-009|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPNSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVQAAPHLTCVDASRDELKQIAQEYWDSGIRRIVALRGDLP
KGVDKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTSVYLRFRDRAAAAGIDLDIVPGILPVTNYQTLIKFAGFTNVHVPGWLHKMYEGL
DDDDQATRNLIGANIAMEQVKVLAKEGVKHFHFYTLNRCELSYAICHMLGVRAG
>A0A0L7Z4E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio alginolyticus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASREELIQIADDYWNNGIQSIVALRGD
IPVGGGKPEMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFD
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A2E3AD84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVIDHIKKAPGKTQFTFEILPPLKGQNIQSIYESIDPLMEFKPPFIDVTYHREEYVYKE
LDNGLLEKHVIRKRPGTVGICAALQNKYNVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAIKSETYFKPHKDGHSFASDLVSQIKNLNKGQYLDDEILNTSKTDFCVGVSGY
PEKHMEAPSLESDLHFLKKKIEAGADYIITQMFFDNQKYFEFVEKCKSFGIDIPIIPGLK
PLATKKQLNALPHRFHVDLPEDLIKQVIKCKDNKQVRQVGVEWCIEQSKELKAAGVPFLH
YYSMGKSDNVKAIAEGVF
>C6PS47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium carboxidivorans P7|TrEMBL
MKVTEIMKKKMSFSFEVFPPKSDKPIEPLLDTLEHLYEFNPDFISCTYGAGGTNAGRNME
ICKAIKDSGKSIPVTHYTCIGNTKEKMKQELQRYLDMGVDHILALRGDLPKGWEGTRGDF
NYANELVQYIKSNFPKFTIAVSGNPEKHFESYSFDEDITHLRIKQDAGADYIMTQLCHDV
DQYCWWVEKIRKAGVSMPIDVGVMPILSKDPTIRMAVSNGSSIPRDLAEIIARYGDNPED
FKKAGKEYSAKQIFKFINAGIDGLHIYSLNKWQDVTDIIKDVGIR
>A0A1J1LNW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktothrix tepida PCC 9214|TrEMBL
MNRFRTACSTLDEFIVTAEVAPPKGTDPNHMIEMVRLLKGRVHGVNITDGSRAVLGMSSL
AASIILLHHGVEPICQVACRDRNRIGLQSDLLGAHALGIRNILALTGDPVKAGDHPDAKA
VFDLESVRLLQAIDKLNHGLDWNQKPLPDGATDLFAGAAVDPQSSSWSGLQSRFERKLQA
GAQFFQSQLITDFEKLDKFMTEIAAGTQKPILAGIFLLKSAKNARFINKFVPGVHIPDSI
INRLEQAKNPLEEGILIASEQVKIARQLCQGVHIMAVKREDLIPKILDLAGIKPL
>A0A2E5CUQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVIEHIKKAKSTLFSFEILPPLKGKSINSIYESLDPLMDFKPPFIDVTYHREEYVYKKR
GDGLLERRSVRKRPGTVGICAAIMNKYQVDTVPHIICGGFNKEETENALIDLDFLGVENV
LVLRGDPIKSETYFTAEKGGHRYASDLLTQVKGMNQGIYLDEDLRNSSPTSFCIGVAGYP
EKHFESANMKSDIHFLKKKVDAGADYIVTQMFFDNQKYFDFVDLCRENNINIPIIPGLKP
ISTKKQLTLLPQRFHLNLPNLLVDEVLKCKHDDQVRQVGVDWSKQQVKELIKFGAPCIHF
YTMGRSDNVQKIVSNFA
>A0A7H2Y449|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFERFLEQAQSVNIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKAFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYVEQYRHLELKALEELWNSLWQVT
TGKEFSPEIRHFSRQPTSKQLIKYRQLHVMHEAIFGSKIAKGIGRFIFKASFWDNTLVAK
VLIKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKEKLIPTVPLETRGTSSWKNWYLSVEA
>A0A7H2ZUL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MSCFDQHFAYVTRFSLLPAKPVFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHD
VAPLEASKSYPDSIDKVLHFSGKARDIQDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGR
DGQPRSRYLESVNAVMTAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIIT
QLGYDIEALKQAKAFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAD
EKQAGHTDRVYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYVEQYRHLELKALEE
LWNSLWQVTKGKEFSPEIARFSRQPTSKQIIKYRQLHVMHEAMFGSKIAKGIGRFIFKAS
FWENTLVAKVLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDR
CEFGDRECIHSVKARLAKAVKQTEVLKEKLIPTIAIETRGTSSWKNWYLATEA
>K5YWX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidocella sp. MX-AZ02|TrEMBL
MTHSPVRHTLERWAQGERIAPLPARDGAAPPAISFEFFPPKTEALEAQLWSCIERLARLR
PDFVSVTYGAGGSTQERTHATVLRLVKETDLTPAAHLTCVGATKEAVNEVAQRYWEAGVK
HIVALRGDMPGGAAYAPHPGGYAFAADLVEGLKKVADFEISVAAYPETHPQAASPEADLD
NLKRKLDAGATRAITQVFFDNSIFLRFLDKALAAGIKAPIVPGILPVTNFKQAKSFAEAC
GTSVPAWMADMFDGLDDDIETRRMVSAAMAAEQVRLLQANGIDEFHFYTLNRPDLTYAIA
RILGVKPEAPAA
>A0A1V6BQ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium ADurb.Bin133|TrEMBL
MFIKNLFEKGKQVVSFEVFPPKRDDDLDKLYDTINELKSLNPDYVSVTYGAGGSNRGKAV
EIVSTVKNKIGIEVMAHLTCVNSTVEDIKIVLDQLKNAKIKNILALRGDPPMGSVNFTKT
IGGFGYASELVKYISDNGDWSIGVAGYPEGHIENRDLSRDVDFLKKKIDNGGDFVITQLF
FDNADFYKFRDLCVKKGINVPIVPGIFPILNYKGIKKSTELSGAKFPAKLNEILEKNQDN
PDEVEKIGVEYSSNQAIDLINNGVDGIHLYTMNKSRQIKSIYDNIKNVLKRI
>A0A0R2QZA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium BACL2 MAG-120820-bin50|TrEMBL
MNSAPTFSVEFFPPKDQAGEERLWSALKALEVYKPDFVSVTYGAGGSTRDRTIRITSEIT
ARSGLSTIAHLTCVGSSRDELIEILSQYKVSGIKSILALRGDPKGGPGVKWESTAGGFDY
ADQLVLLASSMGFEVGVAAFPDGHPASKGNFEQDIKVLLEKERCGASFATTQFFFDVKGY
INLVNQIRAKGSKLDIYPGILPITNFAQLKKMSELAGSAIPIEIQRRVEAAGDSPEEVVK
VGIDIASELSKDLLDYGVPGLHFYTMNSAAPTIEIIRRIGLR
>A0A4Z1CYK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseoluteus|TrEMBL
MESIPGVSGRAGALLDGVSLEMTGKDVPRLEEARASLDGGTRINVTYLAGEDAGMRLAAA
RAVREHGFVPVPHLSARRLPSSAELERFLAGLAEAGAVDSVFVVGGDPARPEGPYEDALS
VISGGLLQRYGVRHVGICGYPEGHPAIGDDALWSALTGKAAAIAEAGLAGDVITQFGFDA
EAVLTWLEALRERGVHLPVRVGVPGPAGVRRLLGYATRFGVGTGASVARKYGLSLTNLMG
TAGPDRFLDDLAAGYDPSRHGAVKLHFYTFGGLRTTAEWITRYRRERG
>B6XU94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium catenulatum DSM 16992 = JCM 1194 = LMG 11043|TrEMBL
MFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVSEYGI
PSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGVEPAGVFEHASDLAVYIRQ
QRPGMKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLDKART
AGIDVPIEAGIMPVMNAKSVLNMSSKCQSKIPEKLGIMLDKWGSDKALLKEAGIAYASEQ
ICDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A2P7BU17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium brassicacearum|TrEMBL
MSFFRQSRRPDLGTNIRVSFEFFPPKTEVMEERLWETVTRLAPLNPEFVSVTYGAGGSTR
ERTARTIKRILTETDVNAAAHLTCVDATKEEVDTVVREFAAMGVKRFVALRGDPASGVGA
HYKPTPGGYENGADLVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVEKVRRAGIYIPILPGILPIHNFTQVTNFCSKAGTHIPGWLTERFD
GLENDPQTHALVASAVAAEQVLDLVERGIQDFHFYTMNRADLAFAICHLIGIRPGGTALE
ANLAGAAA
>A0A7W2A6R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. S1E-3|TrEMBL
MTTPAVSFEFFPPRNLDASFRLWDTARALSPLGPDFVSVTYGAGGTTRQLTHEAVTALTN
HYGLNVAAHLTCVDASREETMQIVEEYAQAGVREIVALRGDAPQGQSVWTPHPEGFASSV
ELIEAIARRGDIAIRVGAYPEPHPDSPGTAADVAFLKRKVDAGATSAITQFFFDADTFFR
FRDACVAAGINVPILPGILPIQSWTGARKFAERCGTSVPDWAIAAFEAAGKEGEAALAQD
LSVRLCRDLLAGGVEHLHFYTLNKPDLTLAVCRALGAAKKGLAA
>A0A8H2Y1U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKLTDKLANHTSNLPYFTFEFFPPRTDQGYSNLLTRINGLAGLKPIAASVTWGAGGSTRD
RSLDLAGFCQADNGLDTILHLTCTNMEKGTIDEALTTAMERGISTVLALRGDPPRGEEYW
IPADPRFRHAEDLVTYIKQHPTFGNHFCIGVAGYPDGHSEGGSEEEQLVHLKRKVDAGAE
FIITQLFYDVEKFKSWLRKVRDTGITAPVIPGVMPLQTYATFLRMTDLCKATVPQHIQAN
LDAIKHDDQLVKEYGVSLAVSMIRSILVDGDIKGVHFCTLNLEKSVRKILDELGWTHDSV
HHNQIIIDASQSPHILPSSADAPHPVTFTISPSEATQHAATSLAEHTRTGTVRTAAEAID
SGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPPHVAISQWGRPTTEQDLSNLFLAYLND
KTSTTPFSPEPLSNESATILPHLVSLTKKGLWTVASQPAIDGALSSDSVVGWGPKDGRVF
QKSFVEFFATEADLEKVAKAIEDSGDGWVTFFAGNNDDGFLTNIPDSGSNAVTWGVFPGK
EIAQPTIIDRDSFLAWKDDAFMIWHDFGLCYPPDSPTRKLIEEVTKTRWLVSIVHHDYKD
SNALWDFLAKHLG
>A0A7C4CF25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium thailandense|TrEMBL
MKVVDKILRQKVLSVEIIPPKKGEDVEEIFKALDKLLEFDISFVNITRHPVEVEYVEFED
RIEKVYKMKRPGTVGLTAALLRRYGNEIEVVPHLICKGMNKFEMENLLIDLWIMGVENVF
VVRGEETKTPQRGDYTYSYELVEQIAKMNEGKYLYMDIPERKTNFCIGVAGYPEKHFESP
NLDEDIYFLKRKIDAGAHFVITQMVFDADVYADFVKRCRKVGVDVPILPGVKPVVSLKSV
YTIPKKFFVNIPQSLLERMKNARTESEEFEIGVNFTVKLINELLEKGAPGIHLFTMGRGK
ETHEVLRRLEKFS
>A0A846ZF31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc holzapfelii|TrEMBL
MTKIDTIYHTKTGPVLSFEIYPPHPTRRRALYAALANLEPKKAGVDFISVTYGAGGQNNQ
LQTHDIAETIQNDWGIPVLHHLTGINQTPNRLQQLLEKISTTGIENILAVRGDVSELSQG
THDFPFAKDLIQAISKTQQFCVGAAIYPEGHVDNPATGINIEGVKSKMHAGTKFLISQLF
FDNQAFYRMQETLSSQRIHLPVSAGIAPIISPQHVEKLTYLTGSSLPAQLTKLIHKYQHD
PAGFRQAGMTYALKQVYDLIDHGVDGIHIYAMNQQDVLTTMIPKINQYIQNKKTDGLSPK
ENKHA
>A0A1S7HKI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygosaccharomyces parabailii|TrEMBL
MSIRELYDAKEGPTLSLEFFPPKTEAGKQNLLDRMQRMSALDPLFITVTWGAGGTTAEKT
LELASLAQKNLNLPVCMHLTCTNMEKHIIDDALMKCKISGIRNILALRGDPPIGQDWSDL
EAANSEFKHAVDLVRYIKTHHSGEFCVGVAAYPEGHCEGEAEGYEQDPLKDLPFLREKID
AGADFVITQLFYDVEKFLSFEVLFREQVSSEIPLIPGLMPINSFLLFNRAAKLSHASIPQ
SILQKFPPEIQSDDDTVKSIGIEVLIDIIERIYNSTSGRIKCFHFYTLNLEKAVAKIVAN
SPTLCNTLEEGEDENEEAATSEPEQDKEGDIVLEDALGVNVKNLINESRKRRRQSSNVSN
ISSELTSNRVIIGQRTQQGVGAPSRKVVVSISQGSGTLGQNATWDEFPNGRFGDSRSPAF
GEIDGYGPTIKVGNKKAYELWGSPQKIKDLQMIFIKYLEGSIDSLPWCDLGLSAETALIQ
EELIQLNDRGLLTLASQPATNGSCSTDKIFGWGPANGVVYQKAFVEMFVPRYMWENGGMK
RKLEQYGRAKLTYYVTDSRGNFETNLKPNSSNVVTWGVFSDSQVVQSTIVSEDSFKAWSD
EAFSIWLEWAKLFPRNTPTNSLLRQAHQEYCLASIVHHDYINPDELWEILLA
>A0A401U524|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseotalea sanaruensis|TrEMBL
MKVIDHIKNAKDKTLFSLEVLPPLKGENIRTLFDHMDPLMEFKPPFVDVTYHREEFVYKK
RENGLLEKKSTRKRPGTVALCAAIQNHYKVDTVPHIICGGFTKDETENALIDLHFLGIEN
ALVLQGDGIKNEGRFVADPDGHRYASELLQQVVNLNQGKYLDEDLLNSTPTNFCIGVAGY
PEKHFAAPNLKTDLKYLKNKVDLGAEFIVTQMFFDNSKYFEFVKQCREIGITVPIIPGIK
PITTKAQTSILPTIFYIDLPEELSDAVDKCKDNAAVKQVGIEWTVKQSKELMKAGVPSLH
FYSMGKSDPIYKIAKELF
>A0A177V5Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tilletia controversa|TrEMBL
MPATTPPAAATPRGDDSWKITAKLAKAERENRIWWSFEFFPPRTAQGLNNLYDRIERMSD
LGPEFVDITWNAGGRSSDLTSSLVKTVHNYFGLETCMHLTCTNMPREKVDTALKDAKEHG
CRNILALRGDPPAGESQWEAHAAGFTCARELVEHIRAQYGDYFAIAVAGFPEGHPESTEG
REKELEHLKAKIDAGADFIFTQMFYDFDIFARWVKEVRAAGITVPIIPGVMPIQNYGGFE
RAVARFRTFVPQYFHDALDPVKNDDQAVRDVGTQLVGDMCRKILESDLGIRGLHIYTMNL
ERGSRMLLDYLGLTPSVNQIKQLPWTPSLTPKRREEKIRPIFWANRAKSYLSRTETWDEF
PNGRWGDARSPAYGDVNAYGVSLNLTDAEARELWGAPESLDDVKALFQKFCSGDLKALPW
SDTPVAKETSVIGSQLEKLNGRGFLTINSQPAVDGAPSDDKVHGWGPSNGYVYQKAYLEC
FVAPERLDEVIAHFDRNPQITYHAVNAQGDMRTNTQSDAPNAVTWGCFPHSEILQPTIVE
SISFLAWKDEAYELGRKWATVYEPSSPSRKLLQGLFDSWFLINVVHNDFKQPDAIFKVFE
SLGAETNGTNGHA
>A0A5D8Q886|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calorimonas adulescens|TrEMBL
MGLAQKLESGGFAVTAEMAPPKGTDFSRFRQCARGVKGMVDAVNVTDFQSAVVRASSLGA
SVILVEEGLEPVMQITGRDRNRIAIQGELLSAAALGIKNVLALTGDHPSVGDHPQAKGVF
EMDSVNILQTAVTLMSGKDLAGNALAGTPQFFLGASVTPVYDPIELQVLKMKKKINAGAK
FFQTQAVYDIELFKKFLEAARGIETKILVGVIPLKSPGMANYMNKNVPGIYVPEEIIERL
RKSQDKVKEGLKIAAEFINEVVQQKLCDGVHIMAVGAEENVPELLEMCGFKKTE
>A0A1F8RB42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_60_22|TrEMBL
MSLKSKLESGKFAITCEVGPLKGTDITEVEEAAALLKDKVDAANVTDQQSSVMRLGSLAT
SGILINKGLEPIYQMTCRDRNRIALQSDLLSAWVMGIRNVLALTGDLPALGDHPAAKPVY
DLDSVTLLHAIGRLNAGFDIAGNELKGKPAFFAGAVVKVDSDTEASMELQIAKLERKVAA
GAKFIQTQAVYSADSFGKFMKRVAKLKVPVLAGVIPLKSAGMARFMNKNVSGVLVPEELI
EKMADAEDKTATGIQICADLIKKLKPLCQGVHIMAIGWEKKVPSIIQAAGL
>F9DFJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella pallens ATCC 700821|TrEMBL
MPIILLTILICYSLLHLRYYFNPSTQQQNRTLWNTGLIVSPFITCTANFQPIE
>A0A1S9BX07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oribacterium sp. C9|TrEMBL
MRIIDILNSGKVTLSFEVFPPKKIENFESVQQATEDVAALHPSFMSVTYGAGGGTSEFTL
NIAKNIRDKHGVEVLPHLTCVSSTREHVHNMLQKFKENGFENIMALRGDIPKDGTPHDDY
HYASELIADIKAHGNFCIGGACYPEGHVECAHKDEDIKNLKLKVDAGVDFLTTQMFFDNA
EFFNFLYRLRENDIRVPVLAGIMPITNAKQLGRSVALSGTTVPTRFKEIVDKFGDHPEAM
KQAGIIYATEQIIDLIANDVKHIHVYSMNKPDVAEAIQKNLSEILKV
>A0A349QNI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp|TrEMBL
MRLTELLNTEDVTISCELFPPKQGAQLDNYKKIVGDMAALKPAYMSVTYGATGGTSDYTV
ELANEVRNVNHIPALAHLTCASSTKEKVASVIQELKEKQIENVLALRGDIPQNADFPLPN
QYKHASELIYDIKSQGDFCIGGACYPEGHPESQTLEEDLIHLKEKVDAGCEFLTTQMFFD
NNILYNFMYKALKHGIDVPVVAGIMPITNANQVKRSIALSGSLVPRRFLAIVDRFGSDPA
AMKQAGIAYATDQIIDLIANGVNHVHIYTMNKPDVAGAILENLSDIYVRD
>A0A1C6S285|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora inyonensis|TrEMBL
MALGLPSVLPNSQPSIGELIRDCQPTFSFEFFPPKTPAGETLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVTVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGDPTGEWVPHPEGVHYAEDLVRLIRDSGDFSVGVAAFPYRHPRSPDIASDTDYFVR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILPGVMPVTQLATIARSEQLSGAPF
PPALAERFAKVGDDPEAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWRNIQ
VGARV
>A0A7Z9YUT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
SGGKRLEKILQFAEDAKKDGRIKAFSITDNPGGHPALSPTSLGLDIQAMGISPLLHFSLK
DKNRNMAESQLFECHRHDLLNLLVLGGDYPRDGYHGQAMPVFDLDSTQLLSLIDRLRHHS
TVKKGAPGQAMDLPSMDFFAGCVVSPFKTLESEQVWQYVKLLTKVKCGARFVISQLGYDM
IKFEELIDLIRDQQLSIPVIANVFVPNLAVARVMNQGKVPGVILPDNLLQRMESESRSED
KGEEARLLRAAGMVAVLREMGYAGIHLGGNNLDFDKISFLLDKAETFDGKELREEVHFPE
PFTWYLKSDCSRKPRKQKLSFLFSLNDMVHSQVFDDKGKLYPMARKISLTALKNKYVNRL
YTLFEHICKKLLFHCRMCGDCTLAEASYLCPQSGCPKKMINGPCGGSINGYCEIYPKERL
CFWVRSFHRGPEPDCRDMHELDSLPPKDWSLDQTSSWINFFSGKDHNGRKHRDQS
>A0A7X1J5E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PSKA01|TrEMBL
MALGTASTRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGTTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPQGLTYAADLVELIKTSGDFCVGVAAFPAMHPRSAEWETDVRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVDAAGCATPIIPEIMPIASVKTLERIPSLTNAAF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPSRA
>A0A317QRF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus normandii|TrEMBL
MTRSVRELLASSRPTWSFEFFPAKTPEGEAQLWTALRELERLRPSFVSVTYGAGGSTREG
TVAVTERIAAETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQAD
WVKHPQGLEYASELVELIRSMGDFSVGVAAFPERHPRSPDFDTDVEMFVRKCRAGADFAV
TQMFFRVEDYLRLRDRVAARGCDVPVIAGVMPVTNARQIARIVQLSGQAFPEELAARFAE
LDGDAPEDKAAVRAYGVEVATAMCRRLLDEGVPGIHFITMNRSTATREVFTNLTGAATSV
PSTLAVP
>A0A1F3A672|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_66_14|TrEMBL
MSPDTGPLSTSAGTSEFPARTPQRLRVSFEFSPPKTETAERTLWETVTRLTPLQPTFFSV
TYGAGGSTRQRTHETVARLKSETGIDAAAHLTCVAATQGEIDEVARAYWDAGIRHIVALR
GDPPSGMGGKYSVHPGGYENAAALVAGLKRIGDFQISVAGYPEKHPDSPDARADLENLKR
KVDAGADRCITQFFFDADDFLRFRDHAAAAGVHVPIVPGIMPVTNFQGIARMAGLCGSKV
PAWLAELFDGLEDDLETRRMIAATVAGDLCRRLRDEGVDQFHFYTLNRADLTFAICHLLG
VRPPRNGASK
>A0A0S9QA39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Leaf285|TrEMBL
MTDGRGRSLADLIQRGERSFSFEFFPPKDAAGEEQLWQAVATLEAYRPTFVSVTYGAGGG
TRDSTVRITGRIARETSLLPMAHLTCVGHTRGELESILDEYAAAGVHHVMALRGDPSDGP
RAPWTPTEGGLTYATELVELARARGDFRVGVAAFPEGHPSAESLDHDADVLVAKARAGAE
FAVTQMFFRAADYFALVQRVRDRGVDLPILPGIMPILNLKAIRRQGELIGTEVPEEVVAR
IAAHDGDAVSMRAEGIAAAAELCEELLEGGAPGLHFYTLNRSRATLEIFEKLDVSV
>A0A3N0W8U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa FACHB-524|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPVDN
>A0A2G9H6P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Handroanthus impetiginosus|TrEMBL
MKVIDKIREATAANESRVVFSFEFFPPKTEDGVDNLFDRMERMVAHNPAFCDITWGAGGS
TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALATIKSNGIQNVLALRGDPPHGQ
EKFVQVDGGFACALDLVKHIRAKYEDYFGITIAGYPEGHPDVIQDGVVSPEAYQNELAYL
KRKVDAGGEVIITQLFYDTDIFLKFVNDCRQIGITCPIIPGIMPINNYKGFLRMTGFCKT
KIPPEIMAALEPIKDNEEAVRAYGIHLGTEMCRKIMASGIRTLHLYTLNMEKSALAILMN
LGLIEESKISRPLPWRRPANIYRVKEDVRPIFWANRPKSYISRTICWDQYPRGRWGDSQN
PSYGALTDYQFMRPRSRGKKLLEEWAVPLKNVEDIYEKFMKFCLGELRTSPWSELEGLQP
ETKIINEQLGSINLKGFLTINSQPAVNGAKSDSPSVGWGGPGGYVYQKAYLEFFSSLENL
NALIEKCKNFPFLTYMAVNKEGSWISNVNKTDVNAVTWGVFPAKEIIQPTVVDPASFMVW
KDEAFELWSRGWAKLYPEADPSRKLLEEVQGNYYLVSLVDNDYVHGDLFAVFKDI
>A0A4R9WR32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.217.01.1.1|TrEMBL
MSIRHQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQIF
LGAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>S3PEW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter rudis CIP 110305|TrEMBL
MSKHVPISFEFFPTKTDVGAEKLRTVHQELQQLNPEFFSITYGAGGSTRERTLAAIYDFY
EKGTPVAPHLSCIGDNKQRIAELLDLYKSKGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFQIEVAAYPEMHPQAASFDTDIQHFVEKVSAGANAGITQFFFNPDAYFYFM
DRVQKAGVDIPVAPGIMPITNASNLIRFADGTGAEVPRWIRKQLQAYGDDTQSIKAFGHE
VVLNLCERLLADGAPALHFYTMNQTDPTRQLVKDLNLA
>D2PVJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)|TrEMBL
MDGFELICEVEPPTRPDLTKVRHQIGVLSPIADDFLIPDNHIGRATVSSVAVANEVQAMG
ARGIACLNSRDRNLLGLRRDLLTAAAYGVEQFLFVHGDDPSEGGRTSQLTVRTMIEETRG
TSFPGCGPFQVGATARLGKVPAWKAEADFLYVQVSFDLDELLRWRDSVDLNIPVYAGVMV
LASAKMAQNLAGLPQLAIPDALVEAVERDRDAGVDAACEQVLRIRESGAFEGVHLVPVSR
YRQVAARLEREL
>A0A066XTW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum sublineola|TrEMBL
MEKIKDKIGALPANANYFSLEFFPPKTAMGLSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKSE
YRNAEDFDVDDVEDFVWAVDLVRYIRKNYGDYFCVGVAAYPEGHADESHPQGQSFEHDLP
YLVEKVQAGADFIMTQLFFDIKAYDKFEKTLKEHPSGAFKDIIIIPGLMPIQSYQMIKRT
TKLSHAKIPDNLMARLDAVKGDDEKVKQVGVDILSELVEQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDHRSEDEEAVIDDGPGVPVSIPAVQLNGLAPIHPAARALSGRRH
SSMGSSDPHNRIIVSSASNPAYETTAVDLSNSEPVNTRANTLAISEGVGAVGREATWDDF
PNGRWGDARSPAYGEIDGYGVSLHMSVTQAIRLWGTPKTVQDINNIFIRHIKGQLGAIPW
SEEELLPESNIIQQELLELNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVEL
FIPSSDWAGLVARLNEVTDKTICFYAANAAGDFVSSDSSGGLVLEGTEASTNAVTWGVFP
GKEIITPTIIEEVSFRAWAKEAFKIWSEWAKVYGKGSESEALLERIRSEYWLVNIIHHDY
VDRDALWKLLSGEREN
>A0A4U8U996|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter bilis|TrEMBL
MLDQLITKLKSNEPFLSVEVSPSLSSTIGQGVIDELESLKVADCFVCTDSPLARLKPSSI
LSSIKLQNALQKPLICTLSMRDRNSIALCGDILGANEFGLRAFLSLSGDGVKNGDCTGAK
GVFEESSLKLGRIIDRLNQGIAANGKVLKDSVETIYNFSVINSYANNTESLKKKMLKKLS
NSLVQGLFTQPVFSLEAARFLLESMESINKELGQNCVMILGFFPVLSYKVALFLRDKLPG
VYIPDEWVQKLKKASIQGKEVEQKVGLELSNKLFKDLQTLHNKFHFMSANKPSLLREFVQ
D
>A0A291PC47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas beimenensis|TrEMBL
MSAHEHPLGISFEFFPPNTEAGHEKLMRTRDALAARRPRFFSVTYGAGGSTQHRTLNTVR
AVRESGFTTAPHLSCIGSEKAALRDLLVQYREEGIDSLVALRGDLPSGMGGVGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFDRDLENFARKMKAGADLAITQYFFTADAYF
HFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSAAIAAF
GEEVISRLCQRLLDGGAPGLHFYTLNQAEPTLKVLDNISA
>A0A838KDN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporichthyaceae bacterium|TrEMBL
MPGRSPSIRELLASGRRSYSFEFFPPKTDEAERKLWTVLRRLEALRPTFVSVTYGAGGST
RERTVAMTERLARNTTLMPVGHFTAVDHSVPELRHIIGQYAAAGVRNVLALRGDPPGDPT
AEWVRHPDGVAYAEDLVRLLKDSGDFCVGVAAFPERHPRSTDWETDTHYFVQKCRAGADY
AITQMFFDAADYLRLRDRVAATGCNVPIIPGIMPATNVRQIERFAKLSNAAFPPALAARL
HAAEDDPDAMRRIGVEAATDLCRRLLDEGVPGLHFITLNTSTATREIYQLLGLPDRP
>A0A8I1PJD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp|TrEMBL
MTVRDLLATSVLVGDGAMGTMLHAAGNSLDQALPALTLTEPGLVRTIHDSYVGAGVDLVQ
TNTFGASRLRLAEYGAADDVARINAEAARLALEAAARADRPVFVAGSVAPAVSVHQRRRV
GADERRAAVREQVEVLVGAGVDVVMLETFGHLDELVEASEVALEVARRTGDVPVVAQATF
GTDHHTLSGHTPHELVAALAGLPLAAIGVNCTLGPQGCLAVLRELRSHTGRPLTVQPNAG
LPRRVAPARFEYDIDADYFVRYTRQLLDAGAALVGGCCGTTPGQLAAAAAAVAEYRAQQP
VTVVETSPSLPVQVSRPGLFDAAGPLVGVELPPPTTGGVDETVALAADLREAGVGLVCVP
ATSGPRAQVNSVDLALHLHDRLGVTTLASVTTWDRTIMALQADLLGAHALGVRGVLCETG
TPPLVGDYPHVDGIWDVDSLGLIELLAGLNEGTDYHGLRLGTKTSFDIGARVNPGSRDPG
RAAAGALDKIAAGAQFLITRPVYEPTGLERVVEAVDGRVPILVAIRPLTGFDEADYLAHE
VPDVTIPDETLAALADAGPDAAAAGVDLALALAEQVRPLTRGIVVTGDSDVAATVRRLTA
CER
>A0A845UDI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidipila sp|TrEMBL
MKIEDFNARLRAGVLVADGAMGSMLYEEMGPQRCFDEVNVTQPEAVFRVHQAYIEAGAQI
IETNTFGANRHKLAAMGLSENVTRFNHRGVKIAREAREAAAREVLIAGSIGPLGVRQMRP
LASEEIVHIFHEQALALEERGVDLFILETFSDLDELLLAIDAIRAFSILPIVAQMAYSEE
VTTVGGIHPREAWSRLSEKNIQAIGANCAVGPQLLLPVLEELATMGDGISLSAMPNVGFP
KRVGDRITYPKSSPEYFSLFAREAAALGVRILGGCCGTTPEHIRAIAQAVKLLAPRKESA
ARTVSVEPRVEPRPAVSREPQSGLWRRIQQGEFAVSVEIDPPKGISLERIFEQVDRVMAS
GNVHAIDINSGTLARVGMDALMLASALEARGVETIPHLTTRDLNTIGLQAMLLGSWSVGG
VRNILAITGDPPSLGDHPETSGVYEVDSIGLVKILTRLNQGMDWAGKTLGGATNFTIAVA
LDPLADPIDREIERFHQKVEAGAHLAMTQPLFDPEQWHSFLKKIGGKSPIPVIAGVWPLT
SHKQAVRLNNEVPGIVIPEAVLKELDAAGTAARERGFAIARRVLDWARTELAGAYLIPPF
KRYEEILEIFV
>A0A7C4IGV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MRIDALFGRGRPTISFEFFPPKTEEGFASLFRTIDELRPLNPSYVSVTYGAGGSTRSRTV
ALVERIQRELGIRAMAHLTCVGHTRQEIGRIVDELWDSGIRNVLALRGDPPAGQSQFVAA
DGGFAHANELTEFVRGRHDFCIGVAGYPEGHPQCLNRTRDLENLKRKLDAGGNFVITQLF
FDNAEFYRFRDTARLMGIAAPIIAGIMPITNVAQIKRFISMCGAKIPHRLLLKLEAVEND
PAAVLATGIEYAVMQCRDLLFNDVDGLHFYTLNRSRATVEIVQSLKVTHAA
>A0A8I1XKD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas manihotis|TrEMBL
MISTDTPHLASTVTDAYSLEVSVKDIGALTNAAPRILPGCAMFIPYLPGQNEAARLAAAR
TVRGLGFEPVPHLSARRIGSPEELQASVARLVDEAGVTRCLVIAGDPATAKGPFPDSVSL
IETGVFERAGIRSVGVAGHPEGHPIMRTTDQWDVLERKCRSIQERGMAPLIVTQFGFDAD
LVVTWLEALRARGMSHPVRVGVPGPASVAVLARYAARCGVGACASVLSNHGISIGKLFGN
AGPDRFVDRLVSRLTQAHGDVRLHLFPFGGIAQLVEWVAQYRSRNASQHRISPGPADQA
>A0A5Z0CXF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MFSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALADIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A8I1TJT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp|TrEMBL
MSSSPTPRATVVDRLDVDRPVFSVEFFPPKDAAGEAQLWGAIRRLEPLDPAFVSVTYGAG
GSSRDRTIRTTERIASDTTLVPMAHLTAVAHSRAELRHVIGSYAAAGVRNVLAVRGDPPG
DPLGEWNPHPDGLSYADELVTMVRSLGDFCVGVAAFPYGHPRSTDADTDFERLVAKVRAG
ADFAITQLFLEPGGFLRLRDRLAAAGCHVPLLPGIMPLTTVRTLHRGPELSGAPLPPDLV
ARLERFSDDPAAFRAAGMDATAELCEKLLAEGVRGLHFYTLNRSPATVELVGRLGLASGR
>A0A249KEP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Planktophila dulcis|TrEMBL
MRSVKSGLTYSFEFFPPKDTEGEERLWAAMSQLESIAPDFISVTYGAGGSTRDRTIRITS
EITARIHVPTVAHLTCVGSTRTELIEILGKYRSAGIKSILALRGDPTGGPRAPWTPTEGG
LSHADELVTLAAEFGGFTIGVAAFPDGHPSSNGDIDKDVQVLLEKEKRGATFATTQFFFD
VTKWKTLVDKLAAKGSTLPIIPGILPVTNVKQLNRMAELSGVPIPAHISESFSKIEDNAD
DVRKLGVEIATKLCQDLLEAGAPGLHFYTMNTSSATREIYSQIKDER
>A0A5E8XGD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.042.01.1.1|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFVDFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAS
GSAAA
>A0A345BY32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salicibibacter kimchii|TrEMBL
MDSKTLAISIQSLTFQPLTSKMKEVMAMMDRQLSVAQFGEMSEPRFELIPTDRIVERATA
ALPPHATLTITCSPKKGVDATIETAIALAPHFARVVPHIAARMIRSGGHLDAMLEELQAN
DLDEIFVIGGDQRQPLGPYHHGFDLLQSLATREHEICRIGIPAYPEGHPDIGSDILAKDV
LAKAPYAHYAVTQMCFDPDQVLAWVRSQREAGLQLPFYLGIPGPVKPDKLIRIATRIGVT
DSIRFLRKNLKLTGKMLRGYDASDLLSTYAPHLNESDNGIAGFHMYTFNELDTLKKIFGR
IAI
>A0A1J4V4J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium CG1_02_42_14|TrEMBL
MKISEILASAKGNRPVFSFEFFPPKTPEGEESLYRTIDDLKTLKPDFVSITYGAGGSTRD
KTVEWSRRIKFELGVETMAHLTCVGASKIEILGLLNRLAEIEIENILALRGDPPKGKSNF
MPAEDGLAHASELISFIRSKWNARFSLGAAGYPEKHPEAVNFEIDINYLKAKMEAGADFV
LTQLFFDNKDYYKFIDTLKNKFGGELPCPVIPGLMPVTAADQL
>A0A2I0DW82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. GutDb-MelDb|TrEMBL
MGFHHAQHATSLNQSLSELKDDINVSFEFFPPSTPEMEKLLWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETDLVAAPHLTLVDASDEELKELAKHYWNSGIRDIVALRGD
LPEGSAKPTRFANDLVRLLRSVADFDISVAAYPEVHPDASNAQADLIHLKKKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDAEIVPGILPVTNFNQTKRFAAMTNVSIPSWLHRQFE
GLEDDATTRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A4V2RP72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacteroides hydrogenigenes|TrEMBL
MKVIDIINRSQSTLFTFELLPPLKGASFSEIEETIEPLLPYSPSYINVTYHRPEVVLREQ
PSGLLERRIIKKRPGTVGVSAGIKYKYGIDVVPHLICGGFTREETEDALIDLNFLGIDNV
LALRGDAEKGAHGFMPEPGGNKLAVDLVKQVNDLNHGKYVDPESTNIQKTDFCIGVAGYP
EKHSEAPNLETDLMSLKAKVDAGADYIVTQMFFNNAKFFEFVEQCRAIGITVPIIPGLKP
ISLKKHLTMLPQIFHIDLPQDLVDAVNRCKNNEEVRQVGVEWGIAQSKELKAAGVPVLHY
YTMGKPDNIEKIVKEVF
>A0A2E3RQ81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHILDIFARDKVTISFEFFPPKTDTGWDALFSRISQFESLDPSFVSVTYGAGGSTRKNTH
DLVLRLLQQTGLDAMPHLTCIGHSDQEIQELLLKYAQAGVSNILALRGDLPSDLAETRTS
DFNHAADLVRAIAKFNDSGACSDPRGFGIGVAGFPEGHPDTPNCLEQMDHLKAKVDAGAD
YICTQLFFNNDLFFDFRERCEIAGINVPIIAGIMPITSTKVMNRMADLAGGMQFPPALLR
TIDRCNEDQDLVSKAGIHWATEQCRDLVDRGARGIHFYTLNKSDATQCIHNTLGLSRVES
S
>A0A2S6BV42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cercospora berteroae|TrEMBL
MDKLTDKIAALPPDATYFSLEFFPPKTQQGFSNLNARLSRMAHSLRPLFVNVTWGAGGST
SVKSLALAEVTQRELGLTTCLHLTCTNMSRKLIDEALEQAKVLGIRNILALRGDPPRSDE
YRDDSLPDAGEDDSNKDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPYLVEKTAAGADFIMTQLFYDVGAYHKYENRLREHESGLFKKIPIIPGLMPVQSYQIL
RRTTKLSHAALPQEILKRFEAVKGDDEAVKRVGVDVLSEIVDTMKHSEFAGPRGFHFYTL
NLEKVVTQILEGNDLIPPSSPDVELNLENQAVAVEETDDFVIVEDAKKLQHRRKSSMANS
NPRNRVIISHTRASSTSSNRPSSAYEAFDDEAGVPKDKINSRANTLAISEGEGALGREAT
WDEFPNGRWGDARSPAYGQIDGYGVSLHVSVPEARKLWGEPKSVEDISVCFRRHLEGEID
SMPWSEETLQPETLTIKNELLSLINKGWWTVASQPAVNGIRSTDPVFGWGPRNGFIFQKP
FVEFFIPNDEWQKLQTRLIENPQITYFAGNAKHEFFSNDTDSVNPVTWGTFTGKEIITPT
IIEAVSFKAWCEEAFGIWSEWQRVYKPGSESSKLLERIRKDYWLVSVIHHGFLEPGALWN
DLLDENSNGV
>A0A8C7VT83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
LLFRRHSHTGVGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTESGDHWFSLEFF
PPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSNKETSSMMIASTAVNYCGLESI
LHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKHIRCE
FDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVRDCRA
IGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIRNYGIEQTVGM
CRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPI
FWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEEL
TSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDELLAPETNLMMDELDKVNRRGVLTINSQ
PTINGKPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPRVNYHIVNVHG
QNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPS
RMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPTEQPVEQPAEESPV
EDQSPK
>A0A2U4AZP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tursiops truncatus|TrEMBL
MDRPKPKVLPAGHCCPSLGMRAWEAGSARFSVTPSISRSSAMVNEPRGHGGPSPRWEGSS
SGSESSKDSSRCSTPVLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKRLGLKNILALRGDPIGDQWEEEDGGFNYAVDLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEAGLKHLKEKVAAGADFIITQLFFEADTFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDDAIRNYGIEQALSLCRELLASGSVPGLHF
YTLNREVATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGDNITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKVSPCVCACACLCVRAGRGLRPVGRAVGQAV
>I3MA17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ictidomys tridecemlineatus|TrEMBL
METGGLGGPTAHSEGSSSGSESSRDGSRCSTPSLDPERHERLREKMRRRMESGDKWFSLE
FFPPRTAEGAANLIARFDQMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLE
TILHMTCCRQCPEEITGHLHKAKQLGLKNILALRGDPIGDQWETEEGGFSYAADLVKHIR
SEFGDYFDICVAGYPKGHPDAQSFEDDLKHLKEKVSAGADFIITQLFFEANTFFHFVKAC
TATGITCPILPGIFPIQGYSSLRQLMKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAV
SLCRELLASGLVPGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWAISAHPKRREEDVR
PIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELRDYYLFYLKSKSPREELLKMWGE
ELCSEESVFEVFAHYLSGEPNRHGHKVTCLPWNDEPLAAETSLMREELLRVNQRGVLTIN
SQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVHYHIVDV
KGENVTNAPELRPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYDEES
PSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPAQSERESEGL
>A0A4V1EE01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia umbonata|TrEMBL
MADHNFSIEFFPPKTAEGAEKLRATRAKLSELHPKYFSVTFGAGGTTQRGTLETVLDIMS
AGEQAAPHLSCVGGTRESIRAILNEYKSHGIKRVVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQAKSPQTDLDAFVRKVKAGADSAITQYFYNADAYFQFVD
AAQKAGVTVPVVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQVAPTTALWQRLVK
>A0A2M9EZM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseomicrobium excrementi|TrEMBL
MKRPFLEQLRDRVLVADGAMGTLLYSYGVDHCNEELNFSHPEDVLRVHQQYIEAGAEVIQ
TNTYAANYVKLARYGLQEQVKAINTAAVRLAKQAAGEEVYVLGTIGGLRGIKQDIPLDEI
KRSFREQLYIFLMEGVDALLLETYYDFEELETVVQIAKQECELPIIAELSMHEVGVLQNG
WTLAEGLSRLEGLGADVVGINCRMGPFHMLTALKNVPIPQKALLSVYPNASLPQLEEGRY
TYAEEFSYFGDIAEELRQQGVHLIGGCCGTTPGHIQAVSERLKDRTPITEKQAIPLKAVR
KVVEPSEESPLLQKVRNETTILVELDPPKHLNTDRFYEGIEALHKAGADALTLADNPLAS
PRVGNDAVAAIIKQRYGANPLVHLTCRDRNLIGLQSHLMGLHELGVQDLLAITGDPAKIG
DFPGAASVYDLSSLELIELIKQNNKGYSFSGKSLERPTQFSVGAAFNPNYRHMDASVKRL
EKKVAAGADYFITQPVFGIEQLHALAEASKQVDRPFFVGIMPLLSSRNAEFLHHEVPGIR
LPDDTRERMRLAGEDPKRALEEGMAITKELVAEAVKLFNGIYLITPFLRYELSLELIHYI
TSRKQEESHDQLYI
>A0A7G5Z141|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas alpina|TrEMBL
MTISINQLEEARRALEAPLFADVAGDALVSFEFFPPKNDKMEEAQWEAVKALEPLGPQFV
SVTYGAGGSTRERTHAAVARIERETSLTAAAHLTCVEATKEEINEVAEGYWAAGIRHIVA
LRGDPPVMGTKFVSHPGGYENAAALVAGLKQLHPFEVSVAAYPECHPDSRSVEADLDNLK
RKLDAGASRAITQFFFSPETYFRFRDRVAAAGITAEILPGILPVSNVAQTRKFAAMCNAE
IPDWMGRLFEGLDDHPGTRQLVAATIAAEMCRKLYAGGVRGFHFYTLNRAELSFAICHLL
GIRAKSVPATIATAAAA
>A0A6V6ZGY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria sp. THAF57|TrEMBL
MTKPEISFEFFPPQSLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLPVAAHLTCVDATREETLAIADSFAKSGVQDIVALRGDPPKGQDSFVPHPDGFQNSV
ELIAALAETGKFNIRVGAYPDIHPEAQNARTDVDWLKAKLDAGADEALTQFFFEAETFFR
FRDDCAKAGIDKPIVPGILPIENWKGARNFARRCGTRIPAWVEQAFDKAVRDDREDLLAT
ALCTELCSDLIEGGVDKLHFYTLNRPELTRDVCFALGITPKTELQNVA
>A0A4V4LJI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRHVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEIAAPEAPQ
KVNGATNGEKHEEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A315WK88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. AM|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQRLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDLDIQRFCDKANAGANAGLTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADSTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A1R3VIH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium prunaredense|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRQLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVCG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A124JZ85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. FSW06-99|TrEMBL
MTTATATALNAILPTRRLADQYSLEMTAKDTASLAEAAPLIAPGTRISVTFLPGEEPDAR
IAAAAMVRRLGFVPVPHISARRLGSSAELEAYLEALIAQAQVNEVFVVAGDPPTPLGPFE
DALAVIRSGLLARYGIGHVGISGYPEGHPEIGHDKLRKAMLDKQAELHAQSIDYAIMTQF
GFDPQPVLHWLAQIRADGVHGQVRVGVPGPTSIKTLLRFATRCGVGASASVLKKYGISVT
RLLGTAGPDRFVNALANGLQPDLHGDVALHFYPFGGLTRTAQWVAEFAQTARGATR
>L7VMT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Uzinura diaspidicola str. ASNER|TrEMBL
MKITSHIANIKKTIYSFEILPPLRDHNILEIFNTLYTLIEFNPPFVNVTSHRDNEVQKRL
RRTGTVSICGAIMSKYEIDAIPHFLCRGFTKQMTEDALIELNFLGVYNILIIRGDMMKFT
TETSAHSYSIELVKQVVALNNGIYLDEALKNRHASDFCIGIACYPEKHFEAPNIEEDIFR
LSEKIKAGSYFVMTQMFFDNNQYFEYIEIMRFAGLEVPIIPGIKPISSIDQLKSIPSNFY
VNIPTKLVKKIINYKKDIFYIGIKWALNQSIELKEAGIPIIHYYTMNKPDNIYQIVIELI
>A0A352WYF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKIINLLHNDRCSLSFEVFPPKVSSSFDEVKPAIEKIAQLKPSFMSVTYGAGGGTSSYTL
DIAEDIRNRYGVPTMAHLTCVSSTRETVTQKINELKKAGIQNVMALRGDLTPEMKLSDSK
HWDYSHAVDLIRELKSSGTDFCIGCACYPEVHPESKHQTDDIFYLKEKVDAGCDFMTTQM
FFDNNLLYNFLYKIREAGVTVPVVPGIMPITRAIQLKRAIELSGSFIPQRFKAMVDRFGG
DDRAMAQAGIAYATDQIIDLYANGVKHVHLYTMNKPEIARAIMNNLSSIIGK
>A0A248QFQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nasuia deltocephalinicola|TrEMBL
MIILKFNIELSFEIFPFKNNDLLKNFILFKKKILIYPYFISITFGAIGKSISDNINTIKF
FIKKNINIVPHISCINLNLNNFKKNIYYYYINNIDKILILKGDEINKKNNYYSYNLIKLI
KYIFLNFFKIYIAIYCEFHNNSYNYKFDLKNSIIKLNLKIKYAITQYFYNIDSYFYFFDD
IKKIKKSNYYIIPGVMPIFSIKQIIKFSNLCNTDLPVWIEKRINNYYFNNNDLKKISYDI
IINLFFKLIKFKIKYIHIYTMNNIYYINNILDKILLSNNL
>A0A4S9MDU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MTKLAVTRATMHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRM
AHSLRPLFVNVTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAK
ALGIRNILALRGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVA
AYPEGHSDQSHPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGA
FKTIPIIPGLMPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMV
ETLKKNSYSGPKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAK
ARRRSSLANSAPQNRVVVDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEG
ALGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFAR
HVRGELDAIPWSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPN
GFVFQKPFVEFFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTG
KEIVTPTMIEAVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFT
ENNGLWKMLLEA
>A0A0B9AHC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium subterraneum|TrEMBL
MAKASIIHPNWDKTPDGITDGFSLEMTAKDEASLRDAAPLIPTETPIAVTFLPGEDVGAR
VAATIAVRELGFEPMPHFSARRITSEDDFEGYLRAVVEKAGVTRCFIVAGDPPEPVGPYF
DTSALIATGAFERSGIKAIGIGGHPEGHPNMTEAECWAVLEKKVAEITARGMAPLIVTQF
GFDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVT
NLLGTAGPDKLVDAFARGLGSEHGKVRLHFYPFGGLTKTLEWIHGYNKKHGIGQGA
>A0A0F7N3K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CNQ-509|TrEMBL
MATGIASTRNDRAVTVRELLASGKQSFSFEFAAPKTDKGERTLWNAVRRIEAVQPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVDHSVAELRNVIGQYADAGIRNMLAVR
GDPPGDPMGEWVAHPQGVSYAADLVRLIKESGDFCVGVAAFPERHPRSTDWDSDIRHFVD
KCRAGADYAITQMFFHVEDYLRLRDRVAAAGCATPIIPEIMPVTHARQIQRFAELSGATF
PPELADRVLAVEDDRAAVRSIGIEYATDMCERLLSEGIPGLHFITLNHSTATLEIYQNLG
LHRRS
>A0A542XPJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinispora arenicola|TrEMBL
MALGLPSILPNPQPAIGELIRDRRPTFSFEFMPPKTAQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRHVIGRLAAAGVRNVLAVR
GDPPGDPTGEWIPHPDGVHYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDAATDTAYFVR
KCRAGADFAITQMFFDADEYLRLRDRVVAAGSDTPIIPGVMPVTKISTIERSAQLSGAPF
PPALAARFERVADDPEAVRRLGVEQASEMCRRLLDEGVPGIHFITFNRSTATREIWRNLR
SGDTE
>A0A418IP67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus xylosus|TrEMBL
MSQLLNKLKSNILVADGAIGTILYSEGLDTCPEAYNLNHPDKVERIHRTYIEAGADIIQT
NTYGANFEKLKVFGLEHRVKDIHQAAVKIAKKAANDDTFILGTVGGFRGIKQEDLELSSI
QYHTEIQVETLVNAGVDGILFETYYDLQELTNIIEATKRKYDIPIIAQLTALNTNYLRDG
TEINHALQQVTSSGADIVGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSQF
KYSDNASYFGKVAKQLINEGVRLIGGCCGTTPEHIQYIKSSVAGLNPVTQKDVIPITKYI
NNTEKEPQKQNLKSKVENRPTTIVELDTPKHLDTETFFRNIKKLDDAKIDAVTLADNSLA
TVRISNVAAASIIKQRYDIEPLVHITCRDRNLIGLQSHLLGLSLLDINEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKTKTSFNIAGAFDPNVRKLDGAVRR
LEKKLESGMHYFITQPVYSKEKIKEVYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEEILEQFEAVKDDKGKTKDLSLKLSKELIDTVHEYFNGLYLITPFQKVDYTLELANY
SKTITSTKQEAIL
>A0A853DGE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allobranchiibius huperziae|TrEMBL
MSIPDLLSAGPPSFSFEFMPPRDEAGEAVLWESIRRLEQVRPSFVSVTYGAGGSTRDGTV
RVTGRIQRETTLTTMAHLTCVGSSLASLRQVVGEYADAGIRNILALRGDPAGGLGTPWTA
HPEGLDHADQLVGLIGSLGSFTVGVAAFPDKHPESRSLEDDADALVRKADAGASFAITQM
VTDVDAYLRLRDLVAARGRDLPIVPGLMPVTYASQLDRMTKLNGQPLAADVVRRIEQVAH
DKEAVRRVGVAICTEHADRLLDEGAPGIHFITMNRSTATLEVYRNLASGRSAVPVGAVSG
>A0A6L8PX73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus anthracis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2G2WQ85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum baccatum|TrEMBL
MKTNEVLELVGTSGIGAFRILEGKPGKASRFAKMVYSHCDLFVSFCVISLTDLSSRPKNW
VRRTFVDARADLIITQLFYDTDIFLKFVNDCRQIEINCPIVLGIMPINNYKGFLRITGFC
KTKAIANALCGQESENSQEALRVGYYSEAACCKAVIANALHDQESENSQEALRILDIILR
VKKSMKLLFVYAASRFAVEVT
>A0A841F2C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. JGP012|TrEMBL
MKADLRTAMKQRVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGAEI
FETNTYSANFDKLSKFGLESRVEEVNRAGVRIAKEVAGTDGYILGAVGSIRGGKRTNVST
SELKRFYQQQISALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGVPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFADLGARIIGGCCGTTPDHITAIKQALSEYVPLPIAEPDPAE
SQPRIVLHEHVDERAGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRALVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDPELIVKMSEATKHLDIPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVTIAKELLDVATEHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFHPNNQLQ
>A0A7U8KT47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella melitensis bv. 3 str. Ether|TrEMBL
MGFYGLSCRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A7C1ZVA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioploca sp|TrEMBL
MTSQIPALTISCEFFPPRTEKGVLKLRQTREQLQALQPAYFSVTFGAGGSTQEKTFETVV
EIQEQSDFDAAPHLSCIGSSGENVLKLLQNYQAHGIRRIVALRGDKPSGWAGPLGDFRYA
NELVEFIRTETGSHFHIEVAAYPEFHPEARSAKADLDFFKQKVDAGANSAITQYFYNAEA
YFRLLDSCAERGIDIPIVPGIMPIGNYEQLVRFSDTCGAEVPRWLRRRLADFAEDKEGLQ
AFGINVVTKLCERLLEGGAPGLHFYTLNQAGPTLEITKRLGLFSLS
>D9S365|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosediminibacter oceani (strain ATCC BAA-1034 / DSM 16646 / JW/IW-1228P)|TrEMBL
MQNRFKESLLDKNVFSVTWELVPGRGAREKTQEEAIMAAEQAAKGGKIHALTLTDNPGGN
PAILADYLATEVIKKGIEPLVHFTCKDRNRNQIESQLYALDRAGVRNLLVMTGDYTVSGY
AGRPKPVFDVDPIHVLDLISQMNRGLEYPGIKGTIKHQPSDFFAGAVVSPFKATEAEQMV
QYYKLKKKVKAGAQFIVTQLGYDARKFHEVIQFIRQQGWNIPVIGNIYILPLGTARVMNK
NRIPGCVVTDKLVAELEKEAQAPDKGRQARLDRAAKMYAFMKGMGYDGVHIGGHGVKYED
VEYVIEKGEELSKNWMDFIHEFDFPIPGGFYYYEKDPKTGLNTPNPVDRKNRPLDAPVEF
IYRLSTFTHRMMLEPGTPLWKPMQAIARMVDGTSLERPYHAFEHLMKVCLYDCQNCGDCA
LMDVAYVCPMSQCPKNQRNGACGGSYMGWCEVYPNKKKCAYVRAYARLKRFGKEHELDGN
IIPPPNWDLYQTSSWLNYYLGRDHSASRFGIKRYEKKKDKK
>A0A3N4GMR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia oryzae|TrEMBL
MTSSLPALSVVERLAAPPVNGVVHFSVEFMPPRDLEGEARLWRAVRVFERLDPAFVSLTY
GAGGSTRDRTVRIAGELATETTLVTVAHLTAVNHSIAELRALVGSYADQGITNLLALRGD
PPGDPLGEWVRHPQGVEYARELVELISGLGDFHVGVASFPEGHHRARDLDQDTDVLVGKL
RAGAEYSVTQMFFDVEDFLRLRDRVARADPEQAAKPLIPGLMPITSLASARRMTQLSGSV
IPAEVERRFAEAAGDGPEEDRAAVRAVGIDFATETAQRLIAEGVAGLHFCSLNFAKATCE
VLDRLGVGVPDALPTVGAH
>A0A2P8FWT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter jiangsuensis|TrEMBL
MTKVTEYIRRAEGKTLFSIEIIPPLKGQNINELLNSIEPLMEFNPPFVDVTYHREELIDR
VGPDGSIERIPIRKRPGTVGICARLMERFKVDAVPHVICGGFTKDETEDVLIDLHYLGID
NVLVLRGDPEKSAGVFRPKPGGHTYASELVTQVDNMNKGILLHAETEMSPTDFCIGVAGY
PEKHFDAASFDSDFAALKKKIDLGANYIVTQMFFDNQKYFSFVERCRAEGITVPIIPGLK
PLSTRKQLTVLADIFHLEFPHDLVKEVEKCATDKEVRQVGIEWGIQQCKELLAYGVPVLH
FYTMGKSDNVSQIARGVF
>A0A136L0G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium OLB14|TrEMBL
MAKYMNEKIPGVFVPQKIMQRMEVADQKGNAEEEGIHIALELIERIKSKQGVNGIHIMSV
GWEESVPRIIEESELLATNN
>A0A542XB04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Barrientosiimonas humi|TrEMBL
MSAATIPQLLTGERTAYSFEFFPPKDDASEAVLWESIRRIEQVRPAFVSVTYGAGGSTRD
RTVRVTGRIARETTLTPMAHLTCVGSSVSELRQIVGEFSAVGIRNVLALRGDPAGGLGQP
WTPHPEGLDHADELVTLVRSLGSFTVGVAAFPDKHPESGTLEDDAEVLVRKADAGAEFAV
TQMVTDVDTYLRLRDLVAARGSDLPIVPALMPVTRYGQLQRMTELNGQPLAEEVLRRIEA
VKDDPAEVRREGIRIATEHGRRLIAEGAPGLHFITMNRSTATLEVFARLQD
>A0A386PUZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus zhachilii|TrEMBL
MTETNKLPTLSFEVFPPNSQVGTANLTATLDQLEGLNPSFISVTASNHKLDYEKTTIDLA
KYVHDKLHCPTMVHMPAAYVTKKEVDDVLNKLEDMHINQVLALRGDIVEGYTPETDFKYA
SDLITYIKQQKPYFEVSGACYPEVHPDSKNRIDDIRHLKDKVDSGCDQLITQLFYDNEAF
YRFQEECAIANINVPILAGIMPIVNRKQALHVIENCSARLPKKFISILDKYKDNPVSLKE
AGIAYAVDQIVDLVTNNVEGVHLYTMNKSDTAKHIFSNTASLFGLE
>C6W2L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / CIP 107007 / KCTC 52180 / NS114)|TrEMBL
MTKVTEYIRRAEGKTLFSIEIIPPLKGQNVNELLNSIEPLMEFNPPFVDVTYHREELIDR
VGTDGTIERIPIRKRPGTVGICARIMERFKVDAVPHVICGGFTKDETEDVLIDLHYLGID
NVLVLRGDAERSAGVFRPKPGGHSYASELVTQVDNMNKGILLNAETQVWPTDFCIGVAGY
PEKHFDAASFDTDYAALKRKVELGANYIVTQMFFDNRKYFSFVERCRAEGITVPIIPGLK
PISTKKQLTVLADIFHLEFPQELVKEVEQCATDKEVRQVGIEWGIQQCRELLAYGVPVLH
FYTMGKSDNVSQIARAVF
>A0A0K9QZ74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spinacia oleracea|TrEMBL
MKVIDKIKASESSNQILFSFEYFPPKTDDGVENLFDRMERMVSHSPSFCDITWGAGGSTA
DLTLEIANRMQNTVCVETMMHLTCTNMPVEKIDHALDTIKANGLQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHMRSKYGDYFGITVAGYPEAHPDAIEENGLATPESYASDLAYLK
KKVDADADLIVTQLFYDTDVFLKFVNDCRQIGINCPIVPGIMPINNYKGFIRMTGFCKTK
IPQEVTDALEPIKDNDEAVKAYGIHLGTEMCKKILASGIKQLHLYTLNMDKSALGILLNL
GLIEESKIQRPLPWKRPANVNRTKEDVRPIFWANRPKSYISRTMGWDQYPQGRWGDARNA
SYGALSDHQFMRPRARDKKLQEEWAVPLQNIEDIYEMFKNFCLGKLRSNPWSELDGLQPE
TKIIDEQLGNINKKGFLTINSQPAVNGERSDSPTVGWGGPGGYVYQKAYVEFFCSKEKLN
ALVEKCKALKHITYMAVNKGGDWISNVAQTGVNAVTWGVLPAKEVIQPTVVDPASFMIWK
DEAFEIWSRSWAKLYPEGDSSKTLLEQVQNNYYLVSLVDNDYINGDLFSVFTDL
>A0A2G5WWB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. P16a|TrEMBL
MSLLEKLQTNVLTADGAMGTILYSYGIDYCYEELNIEKPEIIEQIHQDYITAGADIIQTN
TYSANANKLARYGLESHVTEFNKAAMKIAKRAAAPGGQFVLGTIGGLRGIRKSDATLDEI
EKVVLEQANALLAGDPDGLLLETYYDFEELSSVVTTLKKITDVPLIAQVSMHDPGVLQNG
LSLNAALHQLESLGADIVGVNCRLGPYHTIQAFDNVTLPEKAFLSAYPNASLLDVEDGRI
VYESEAEYFGRAAVLLRDQGVRLIGGCCGTTPKHIKAAKTQLARLTPITEKVVQPAKPIV
IHEAGPAKHQPLHEKAKTERTVIVELDTPRHLETDDYIKGANMLYDAGVDAITMADNSLA
SPRISNMAMGSIVKMQHNIRPLVHLTCRDHNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELLQLIKKLNEGISFSGKPLRKKASFSISAAFNPNVRVIDRAVQR
LEKKIEAGADYFITQPVYTKEKIIDVYEATKHLDTPIFIGIMPLTNIRNAEFLHHEVPGI
KLSEDVLERMRECGEDRERSTETGLEIAKELIDTAAQYFNGLYLITPFLRYDMTLELYEY
IKKIDQQKERELTHAETSY
>A0A177E8G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfatator autotrophicus|TrEMBL
MVCSFRKCLENPELFTITYELVPGRSTRLRQFQKIIKFAEEATKDGRLHGLTITENAGGH
PALSPAVLGREILKLGLEPVLHFTCKDKNRNQIESTLFARDREGLHNLLVMTGDFPLYGF
MGRAKPVFDLDAVHLLQLITEMEKGIELPPEAPGGGVKLPPMPFFKGCVVTPFKKLEAEL
MPQYYKLHRKIKAGAHFVITQVGFDARKFHELLLYMREEKLNVPLIGSVFITDVRMARIF
HKGIIPGIEITPQYLAQIEEESRQEKDSYRAALIRAAKLVAVLKGMGYDGVHISGGRVSY
EDIAFILDKAEEFYPRWQELVAEFQNAPEGTFYLYRKDPETGLNIPERYEKLAPAQKKPL
MFTLNLWMHDLFFEPGKGFYNFAVKYAQKINGSSFEPWFTRFEYAVKGFLFDCQRCGDCT
LGEMAYLCPQSGCAKNLLNGPCGGSKDGYCEVDSSKKCHYVKVYERLKAIGKRHLLKEGF
IPPRDWGLSGRSSWLNFYLGRDHHRHPVPENFQEPR
>A0A8F2RLK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] haemuloni|TrEMBL
MKISKKLDDAHSCSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYELNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALSKAHASGCQNILALRGDPPLD
GSESTGDFKYAKDLIRYIRKNYGDHFNIGIAAYPEGHPEEEDDVKLLSYLKEKVDAGADF
IITQMFYDADNFISWCSKIRKIGVEIPIIPGIMPISTYSAFIRRAKWSQVKIPEHFLQAL
DPIKEDDYAVREKGTQLVGEMCQKLIDSGYVNHLHFYTMNLERSTIMVLEHLNLIEHVKD
NAVVGDELPWRKSLHPMRSKESIRPIFWQNRKYSYISRTSGWDEFPNGRWGDSRSPAFGD
IDLSATELLRQSPKRAFELWGCPQTLGDLSQILISYLQGEIKSLPWSDGPIGDDTEVLKP
ALIEMNKKGIFTLNSQPALSAVRSNDEVFGWGPKNGFVYQKQYLEFFIHRNALNTLLQRV
EEHNARDAHSVVTYYAVDKQGTLSTNAHDDDINAVTWGVFPGEEILQPTIVEKVSFLAWK
DEVYRLLDEWVKIFHTKSVKEEVEEAKIDAFSTLLTGFGDNFVLCNFVNNDFTSGNNIIF
DLFRDLPVASL
>A0A099D7N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora erythraea|TrEMBL
MTRVVDRLQPGRTVFSVEFFPPRNDDEEQILWKTVRELEPLDPAYVSVTYGAGGSSRDRT
IRTVGRIAQETTMLPMAHLTGVDHSKDELRHVVGSLANEGIRNILAIRGDPPGDPMGEWI
PHPDGILYADELVRLVRSCGDFSVGVAAFPHMHPRSTDIETETDHLVNKIRAGSDFAVAQ
LFLQPEYFLRLRDRLAARDCHVPILPGVMPITTPKVLSKFQHLAGVPVPAEVSNVLDPLA
DDPEAFRAAGIELSTRLCERLISEGVPGLHFYSLNRAKATREVVDNLGLAEAVPQPA
>A0A1V6HNG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin037|TrEMBL
MKLTDIFQVTERTFSFEFFPPRDEIAAVDLGINIGQLIRLNPSFVSVTYGAGGSTRSRTF
DLVDFLKNRVGLNTVAHYTCVGNTRSKTLRDLRTLRKLGLQNFMLLRGDPQAGSRYGFIP
CPGGFSNATELISYARKHIDDCCIGGGAYPEVHPESLNAEVDMQNLKKKVDAGCDFLITQ
FFFDNERYFDFVERARKAGIKCRIIPGIIPLTKYTQLERFVNLSRASIPAAFLDRLERYR
HNPEAIYNAGMDFAIRQCRDLLMLGAPGLHFYTLNKSRATVEIYQTLMAR
>A0A4U9UVP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium thalpophilum|TrEMBL
MKIIDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTEGGHAFATDLLQQVVDMNKGKYLHEDIVTSEKTDFCIGVAGY
PEKHFESPNFNTDFKYLKQKIDMGAEFIVTQMFFNVDKYKEFVIKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVAACKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLA
>A0A058ZJ14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actibacterium atlanticum|TrEMBL
MPAAPRISFEFFPPQSLEASFRLWDTVRALAPLNPGFVSVTYGAGGTTRKLTHDAVATIH
KNYGLNVAAHLTCVDASREETMEIVDSYAKAGVTEIVALRGDPPKGQGSFSAHPDGFQNS
AELVAAIAETGKFHIRVGAYPDPHPEAKGAGNDVTWLKHKIDAGANSAITQFFFEADTFF
RFRDDCAKAGIDAPIIPGILPIENWNGVRKFAARCGAYIPTWVDEKFAAADAAGNAEQVA
TDMAVELCDSLISGGVEDLHFYTLNKPHLTRGICETLGVKAESNIAEVA
>A0A1X3LAC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli TA054|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A286C299|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosovibrio sp. Nv4|TrEMBL
MESQKKFAPTFSFEFFPPQTAEGIEKLRATRRQLAQLDPKFFSVTFGAGGSTRDRTLETV
LEIQSEGYVAAPHLSCIGATSENIRTMLQKYRDGGIRHVIALRGDLPSGMAQGGEFRYAN
ELVTFIRKEFDDAFHIDVASYPEYHPQADSVQKDLQNFKRKVEAGADSVITQYFYNADAY
FSFVDACEAMGINIPIVPGIMPINKFSQLARFSDACGAEIPRWIRKKLESYGDDSASIRA
FGLDIVTDLCDRLLSAGAPGLHFYTLNSAGLTTTIWQRLGL
>A0A2S6SW84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha5_Bin10|TrEMBL
MKNISLLSKKLQEGVFVYTAETTPPDASDMNVLINRTIFLKGVADAINVTDSPGAKVHMS
ALTASIILVQNDIEPILQLTVRDRNRIALQGDLVGASALGIHNILCLSGDNPKNGDQPES
VAVNDINSLTLVKTANLMRNAEQYPSGRKIDPPPKFFIGGAEVPTAGLPDPKKILQKIDA
GVDFFQTQYVFEDSILKEYMNVLEGEGILEKTHFIIGIGPFASAKSAKWMNDNLFGVSVP
NKIIKRLEQSQDQKKESKNICIELIQSFREIRGVKGVHLMGHNKEEVIAEIIKESKMQ
>T0I2Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium quisquiliarum P25|TrEMBL
MTFPFPSVEEARRVLDAPLYADMAGDLNVSFEFFPPKTEKMEEQLWSAIGTLAPLAPKFV
SVTYGAGGSTRERTHNTVARIAKETPLPAAAHLTCVAASKAEIGEVADAYWEAGVRHIVA
LRGDPPQAGCKFEPHPQGYKGAAELVEGLVKRHPFEISVAAYPETHPDASSAQSDIDNLK
RKLDAGATRAITQFFFEPETFFRFRDTVAAAGIDAEIIPGIMPVSNFAAVQRMSAMCNTA
VPEWMGKLFEGLDDLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GVRAA
>A0A0D2QEY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium raimondii|TrEMBL
MPINNYKGFVRMTGFCKTKIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKT
LHLYTLNMEKSALAILMNLGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLS
RTIGWDQYPQGRWGDSRNPSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNH
CLGKLRSSPWSELDGLQPETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPG
GYVYQKAYLEFFCSLDKLDALVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFP
AKEIIQPTVVDPASFMVWKDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNN
YMDGNIFGVFEDL
>A0A1V4HEF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus ferrarius|TrEMBL
MKLDLRTALQQEIITGDGAMGTYLYQMGFPVGISYEELNLLRPETVADVHRRYFEAGARL
IETNTFSANREKLSKYGLEGDVEAINRAGVELARKAVGDDAYVVGAIGSIRAGKRKNVRT
ADVEDSLREQIGVLLDSPVDGLLLETFYDLEELQLALRIIRSMSSLPVICQFANEGTGST
QDGVPLQEAFLRLRDEGADVIGFNCRVGPNGILRSLEKLAPLAGVPFSAFPNAGLPDYVD
GQYTYAATPQYFAESALRFADLGARIIGGCCGTTPEHIAAVAKALQGYVPAAPGTAVPAR
GVRVIEPAPAKPAPPASKPSLLEIVKQRKTVIVELDPPRDLDIEKFMQGSKALQDAHVDA
ITMADNSLAVTRMSNLALGYLVQDKLGARPLIHIACRDRNMIGTQSHLMGLHALGIDHVL
AVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFVVGAAFNPNV
KHLDKAVQRLERKIEAGADYIMTQPVYDAKLIEQIYEATKHLDIPVFIGIAPLASGGNAE
YLHNEVPGIRLSDEVRARMDGLKGPEGRAMGVEIAKELLDAAMPYFNGIYLMTPFLAYEM
CVDLTKYVWEKSNRHDFHLYPLSK
>A0A2E7S087|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MLTLGEIYSGESTAISVEIFPPKTPDGDQALFDTLDRLAVFQPDFVSCTYGAGGSTRDRT
IELCREIQSRYRLAATAHLTCVGSTRDELVEWISRVQAAGIGNIMALRGDPPQGDETFTA
VAGGLEHANQLVELIRGVSSDLGVGVAGYPEVHPEAADATRDLENLKRKVDAGADAVFTQ
LFYVNDSFLRFRDRCGASGITVPVVPGIMPVTEFSRIQRIATLCGAKIPGELSDRLEAVQ
DDRDAQLAVGVEYAVEQCRELIDAGVPGIHFYALNRSQACARILEALGWNTSSESSGEW
>A0A7M2AAS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. JNUCC-31|TrEMBL
MKADLRSVMQERVLIGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
HETNTYSANYDKLSKFGLESKVEDVNRAGARIAKEVAGPNGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIYALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGFTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGASPEYFGQTAVQFAELGARIIGGCCGTTPDHITAIAQALVEYTPAPILEPDPSE
PKPRIILHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRSLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVSFSGKPLKQKAGFVIGAAFNP
NVKYLDKAVQRLEKKIASGADYIMTQPVYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATEYFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A7J9J8M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium armourianum|TrEMBL
KIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTADLTL
DIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDKFVQV
EGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYLKKKVD
AGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTKIPDE
VTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLGLIE
ESKISRSLPWRRPANVFRVKEDVRPIFWYVINVDHPISWLDTCNLLVWLTVQRVTYLGLL
AGXIGWDQYPQGRWGDSRNPSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKN
HCLGKLRSSPWSELDGLQPETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGKYKY
LTGL
>A0A2U9R2H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pichia kudriavzevii|TrEMBL
MKITEKLQQAHRAEDAPATFSFEYFTPKTSQGVQNLYDRMDRMYNLNPLFIDITWNAGGR
SSNLTSEMVHTTSTVLGLETCMHLTCTNMPLELIDNALQQAYDSGCQNILALRGDPPLDG
SESTGDFKYAKDLIRHIRNKFGDYFCIGVAGYPENHPEEADEMKNLQYLKIKQDEGADFV
VTQLAYDVNIFIEWVQKCRQVGITMPIIPGIMPISNYNAFLRRAKWNEVSIPQSFLDRLE
PIKDDDAKVREEGALLMTEFCSKLLESKLINHLHFYTMNLEKSTLMLLENLNLISCASKI
NYENENSKPWRRSLNPSRETENVRPIFWKNRKFSYIQRTNAWDEFPNGRWGDSRSPAFGG
LDLLEHEIIRHSPAKILSLWDKPSNPMELGNLIIAYLENRIHCLPWSDTQVTSEIEPIKQ
SLIDLNKHGVLTINSQPKINGVRSDDLVFGWGPSNGYVYQKQYLEFLLPKSKMNFLISKI
ESVNKEYNYNILNYFIADADSNNVLGSNVIESADVNAVTWGCFPGKEVAQPTIVEKVSFI
AWKDELFLILKKWSNVLKSSLVDAQTQPDENDRLSDLNSANFIESLINEYVLVNIVDNDY
VHPSDRIFSLFNDI
>A0A1Y6EHC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agreia sp. VKM Ac-1783|TrEMBL
MESLLSPAAAHAGCPKSMEYGPCGGVGFDGSCEVGDFRCVFLDDPLVTWHGGASAEPEVV
PRSSGAVEMMALMKARPIVVADFPAKAMDAESLAECAALLAGPVDAALAGDVGHARVQFS
PSYRASLIRAAGLQVWTGINCRDRNRVAIEGELAGLAHIGVAGVHCVTGDHTLLGGRPDA
APVFDLDSTQVAALARAAGHLVSVGESPTTPPVELRAARLLEKTRAGADVCFVNHCGGVD
AVGRFVRESHDVGVTAGFIPCVPMVTDHSSARLLQSFPSLVLPEGYLERILSAADPREEG
ISASVELSLQLLEIEGVAGVNLSGGAGVGREAEFAIALAETAQRLAL
>A0A1P8PP80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter schindleri|TrEMBL
MSQLASHFKYNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKSTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGEFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHKVAGIVITLHMLRVLAQEKQDGLGDNA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVET
KKELVPQLAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASFWENTPAAKA
LFKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVEQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A429YSM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquibium carbonis|TrEMBL
MNQFRFSRRPDIGDRIKVSFEFFPPKNDLMEARLWETTTRLQVLSPDFVSVTYGAGGSTR
ERTARTVGRIRRETDLDPAAHLTCVDASRAEVDEVIAEFMAMGVTRFVALRGDPAEGVGA
RYRPHPSGYANAAELVGALKAQGATDISVSAYPEKHPESPDFATDVDMLKRKVDNGATRA
ITQFFFDNDSFERYVERIRRAGIYVPIVPGILPVHNFTQVANFSARCGTHVPAWLAERFE
GLEDDPQTHALVAAAVAAEQVLDLVERGITDFHFYTMNRADLVVAICHMIGIRGSTAASE
NRPVAA
>A0A133KUZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium breve|TrEMBL
MFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTISKEYG
IPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQAVGEFNHASDLVSYIR
SVKPDLKVFGACYPEGHYQADTIDQDIENLKIKVDAGATHLISQLFYDNEDFYRFLDKAR
AAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRTAGILYASE
QIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A2E8KIT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MVVTPQERYGKNSFELSFELFPPKTAESEAMLWQTVDELMGFEPTLITCTYGAGGSTQTK
TLEVLNGVHVRHPSVAIASHLTCVGSTTDQLREYLRKAEKTGVTAIVALRGDPPQGETAF
TPVANGLHYAVELVNLIKQEFPQLRILVAGYPETHQEAVSTDADLQFLKQKCDAGSDTVV
TQLFYDNADFFRFRERCLAIGITQSIIPGLMPVTNFKQIQRIANLCKARLPSYFTNALEK
AGDDADAQFEVGVEYAAKQAEELISQGVPGMHLYVLNKSPATIRVLEQVGMTRP
>A0A518D600|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pirellulimonas nuda|TrEMBL
MKTLRDAYAGGRFGLSFELFPPKSPAGEAALFHHVGRLVEFEPSFITCTYGAGGSTQQKT
LEIVAKVRKDFDLPVATHLTCVGLTADQLRDYLRQAIEAGVLSVVALRGDPPKGETAFTK
TAGGFGYANELVAMIRGEFAEMGIAVAGYPEKHLEAPDLATDLANLKRKIDAGADAVITQ
LFYHNEDFFRFRDACDAAGITTPIVPGLLPVTNFAQIQRITALCGAKLPQPFIDKLSAAG
DDDDAQFRAGVEFATEQTQQLIESGVAGIHYYVLNKSEAASEVLRAVTLPA
>A0A1V5LRQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium ADurb.Bin429|TrEMBL
MSSHLQRLLESGAFVLTAEIGPPMSADADVVRRHVAAMRGSVDAINLTDNQTAMVRMSSI
AAATIVQAEGVEAVVQMTVRDRNRIGLQSDILGLAALGIRNVVCMSGDHPCNGNHAMAKP
VYDLDSITWLQTASRMTVDGLFFNGDPIKVPPTLFVGAVENPFAPPYDYRPVRMQKKADA
GARFIQTQCTFDVARLREFMARAGDLGLFDRVKVLVGITPLKSVKMAERMYGDVPGVALP
EALLKRMQGAADAEAEGVAIALETIEQVRAIPGVAGIHLMPVFWEKIIPVIAERAGLLPR
PEVPAEPPAEPAVSE
>A0A173WBU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mitsuokella jalaludinii|TrEMBL
MKRISVELVPRDEDALRQELALLGKFQDKVDVINIPDLLRFPIRSWQGAAVAKEYFPASM
PHIRAMDIDLDKELAMKDYLRAHDIREVLVIEGDPPQDMMHEVYPTNSVDVIWKFRKEMP
EVKVYAGIDQYRGSMAQELYRIKRKLQAGAAGFFTQPFFDIRYLSVYADMLQGLEVYWGI
SPVMSARSQSYWERKNHVVFPHAFEPTLDWSIGFAKEVMDFAEREDANVYLMPIKTNLEA
YLAGVLA
>A0A2V7E8R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFDRRLAAGPLLCDGAMGTLLYARGVSIDACFDVLNVNQAKVVQSVHSEYIAAGADC
IETNTFGANRFKLAVHGLASDVHQINLRGVKLARDVRESMGRDVLVLGSVGPLGKYLAPL
GTVTADEARAAFREQAEALLEGGIDAFVVETFSDLTEIALAIETIRTLTDLPIVAQMAFT
DEGVTFAGRSPAEVARTLRELGVRALGANCSVGSSTLYEVLEAMGPEARDVPLAIQPNAG
LPHRIGERLMYLSSPGYMADYAGRMIDAGARIVGGCCGTTPQHIAAMRRVLDARAPASKA
EPRPTSAARVIEALETPGLRTTLAPTLLGRKLEQRSFVVSVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLPTAILVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALGIRNILAMTGDPPRTGDYVNATAVFDVDGIGLLEVLRRMNEGMDATGNGIGEPTSFCV
GAALDPGAPDPGREVERFHRKLEAGARWFQTQPVYDLEVLDRFLARVVGSPVPVLVGVLP
LHSFRHAEFLHNEVPGITIPDGVRARLRAAGDGALRAGIDMAQQLVGEIRSRYAGAYLMP
SFGRFEVVAEVLDVLR
>A0A1V2L923|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyberlindnera fabianii|TrEMBL
MRISHKLQKAHEESDKATFSFEFFVPKTSQGVQNLYDRMDRMYNLNPEFIDVTWNAGGRL
SNLTTDIVSTAQSVLGLETCMHLTCTNMPIELIDNALKDAYDSGCQNILALRGDPPIEGG
EWTAVEGGFTYAKDLVKYIREKYGDHFDIGVAAYPEGHPEESNVDSLIDHLKEKCDAGAD
FIITQMFYDAENFIEWCKKIRSKGITIPIIPGIMPISSYAAFKRRATWCEINIPENFEAK
LQDIKDDDQLVRQAGTELVAEMCQKLLDSGYVNHVHFYTMNLEKSSIMILERLGLITANN
VDFLPWRKSLNPNRTNETVRPIFWKNRKYSYINRTKNWDEFPNGRWGDANSAAFGDVELF
TSGLLRQSPKRAMELWGEPTSVKDISNLVVSYLQGKDWIQYLEFLIPKTKLNNFIQKIDE
INKPFNTSNNDKDNYNILTFFAIDVNDDLNSNTKDDSANAVTWGIFPGQEVLQPTIVEKV
SFLAWKDEFYRIIAEWSHIFEEGSISRQIIKSIIDDYALVNIVDNDYVGNDKIFSLLQDL
>A0A0W0CTI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida glabrata|TrEMBL
MKITQKLADRHKEKPDKATFSFEYFVPKTTQGVQNLYDRMDRMYEASLPEFIDITWNAGG
GRLSQLSTELVATAQSVLGLETCMHLTCTNMPISQIDEALEDAYNSGCQNILALRGDPPL
NAPNGWQPIEGGFNYAKDLVKYIRAKYGDHFDIGVAGYPEGHPEEKERHKDLVYLKEKID
AGGSFIITQMFYDVDNFIQWCHEVREMGIDVPIIPGIMPITTYAAFLRRAQWGQIKIPQA
FLDVLEPVKDDDQLVRDKGSELIVDMCQKILNSGYVKHLHIYTMNLEKAPLIILEKLGLL
PSESEVNANPLASLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAMDEFPNGRFGD
SSSPAFGDLDLCGSTLIRQSGKKSLELWSTPKTIEDVSQLVISYLTGQIKCLPWSDTSLD
EEIDPILDHLLDLNRKMIITINSQPQINGIRSNHKVHGWGPKDGYVYQKQYLEFLLPNEK
VEKLEKQLAGNEMLTYFAVDNKDNLKSNHPDGSKANAVTWGIFPGREVLQPTIVEKVSFL
AWKEEFYRILEEWKWNFQENNELKSAEFIQHIIDNYMLVNIVDNDYISSTDEIYNVLINL
>A0A2V6YTP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPYELSRRLAAGPLLCDGAMGTLLYARGVSLDACFDVLNLNTPRVVQSIHADYIAAGADC
IETNTFGANRFKLAVHGLEKQVREINRRGAALARDVRESSGRDVFVLGSIGPLGKYLAPL
GTVTLDEARAAFREQAEALLEGGVDAFIVETFSDLDEVALAVAAIRAITDVPIIAQMAFT
DDGVTFTGRPAAEVARALCALPVQALGANCSVGSSPLYEVLEQMRPEARNLPLCIQPNAG
LPSRIGERLIYLSSPTYMAEYAERMVGAGARLVGGCCGTTPQHIAAMREVIDRRRPARAE
ARTAAVTVRPVAADISPGLHVARPPTLLGRKLAAREFVVTVELDPPRGHTVEKLVQGAKL
LRERGVDIVDINDGSLGRVRMAVLPTALLVREATGLDINMHFTCRDRNLMGIQGDLLGAH
ALDVRNILAMTGDPPRAGDYANATAVFDVDGVGLIEILRRMNEGQDATGSSIGEPTSFYV
GAALNPVAEDVAREIDRFQRKVRAGARWIQTQPVYDLPLLDRFLERAGGSPVPILVGILP
LHSARHAEFLHNEVPGITIPENVRRRLREAGDSALRVGIEMAQELVRSVRTRYAGAYLMP
SFGRFEVVAEVLDAIR
>A0A2V6Y8A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MTNPLRDALAAGRFCYVVELVASALTREARLLEAASGLARIPAVVAGSVTSYAGGAMGHD
PLRVAAAARARGLTPNIHLTCVSQDRRGLAKSLDDMHALALENVFALTGDYPGARDQPPV
FDLDSVQLVRLIDERRRGGMPFHVAVAVSPFKYTEADCVYQYVKLEKKIAAGADVAVTQV
GWDAPKFAELKRYLDERGLRTPLLGNVYVLGPKTAERMATGRPPGCWVSPELLAAVQAES
HASDGGRQARLERAARTVAILRGLGYAGAYVGGTHDAANIAWIIRRADELAPQWEALVPA
LGYGADGGFYLPARTLSKGAADEANARSRADRVPRLLDWLGHAFPVSRDTWLRRALTRVV
EWIDRRKPAAALLERVELAIKKPLFGCQACGNCVLGHLEYVCPQTCPKQLRNGPCGGTDQ
GRCEVVPDKPCIWVAVYERARASGDLEALKTYVPAPDRQLSGTSSWINYFLDRDSRPTPD
RH
>A0A6N2DU57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MPTVLRPADPRRQRILVPVSSPLPKDVRVSFEFFPPKTAAMEQSLWAAVERLASLHPAYV
SVTYGAGGSTRERTHATVVRLREETALEPAAHLTCVGAVRDEIDAIARLYWEAGIRHIVA
LRGDPPEGADRYQPTPDGYDYACDLVSGLKRVADFEISVAAYPEVHPEAANAQTDLDNLK
RKIDAGATRAITQFFFDVDVFFRFLERCRAAGITVPIVPGILPVTNFARVRQFAGQCGAA
IPPWMADLFAGLDDDPETRKLVAASVAAEQCRALNAGGIDQFHFYTLNRADLTFAICHIL
GVRPQSVASATNAAIKAAAD
>A0A2V6YLZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHALSLRLQAGPLLCDGAMGTVLYARGVSLDACFDVLNLNNPRLVQAIHADYIAAGADL
IESNTFGANRFKLAVHGLEGQVREVNRRGVRLARDVRESAGRDVLVLGSIGPLGKYLAPL
GGVTAEAARAAFREQAEALVEGGADGLILETFSDLAEIALAIEAIRAVTDLPVVAQMAFT
DEGVTFTGRAVAEVVRTLCALGVQAIGANCSVGSSTLYEVLEQMVPAAGSLPLSIQPNAG
LPSRVGERLIYLSSPTYMAEYAARMVDAGARVVGGCCGTTPQHIAAMREALDRKRPAARE
TPRPTITVRAPTAGETVGLRRERAPTTFQRKLEAGEFVVTVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLPTALLVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALDVRNILAMTGDPPRAGDYVDATAVFDVDGIGLIEIVRRMNEGLDATGSSIGEPTAFHV
GAALNPVAEDVDREVERFHRKVEAGARWIQTQPVYDLASLDRFLARAGGSPVPVLVGILP
LHSLRHAEFLHNEVPGISIPDAVRRRLREAGDGAHRLGVAMAQELVREARLRYAGAYLMP
SFGRFEVVAEVLDAVH
>A0A0Q6M8W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter sp. DSM 101952|TrEMBL
MNQYPLSRRSDIGNKIRVSFEFFPPKNDEMEARLWDTVTRLEPLKPQFVSVTYGAGGTTR
ERTARTVKRILQESTLTPAAHMTCVDATREEVDQVIAEFAAMGVKRFVALRGDPKEGVGA
AYQPHPGGYANGAELVGALKAQGDFDISVSAYPEKHPESPDFATDFDMLKRKVDKGATRA
VTQFFFDNDLYERYVERARKAGIYIPIVPGVLPIHSFAQVANFSARCGAHVPHWLAERFE
GLDRDPQTHALVAAAVAVEQVLDLVERGVSDFHFYTMNRADLVVAVCHMIGIRPQPAVQG
SAAA
>A0A3A1Y3I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium GH005|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VSYIRSKRPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGVNVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNADCLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A0D6BRP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Os17|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLAGYNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLKQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLRNFARKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A1M5M6Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosyntropha lipolytica DSM 11003|TrEMBL
MKICEFYKGDIPVLSLEIFPPKRDYPLETVFQTIEELLSLNPKFISVTYGAGGSSRGRTV
EIASRIKKDYGIESLAHLTCVSHTRREVKEILEQLVREGIDNILALRGDPPEDDPHFDFS
KQEYHYAYELIRDAKKVYDFGIAAAAYPEGHRECKRLSEDLKYLKQKVDEGVDFLITQMF
FDNRFYYDFVDKAVAMGINCPIIPGIMPVLNPRQVRRMIYLSGGASIPSKLLDLVEKYGH
KPEEMEKAGIDYASEQISDLLDEKVKGVHLYTMNKSRQIERIVKNVGLA
>W2VMF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium sp. MSTE12|TrEMBL
MHSPLFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGRSSDRTLTARIAHTVS
EYGIPCVAHLTAQYLNKDDVDQALDMFDEAKVSGVLALRGDRVEGAEPAGVFEHASDLAA
YIREERPNLKIYGACYPEKHPQSATLEDDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KVRAVGIEIPIEAGIMPVMNAKSVRRMAGICQSRVPAKLEVMLDRWGGDNAVLKEAGIAY
ASEQISDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A7J5JNU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides thetaiotaomicron|TrEMBL
MRVIDLIHNSEKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLFWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEVLKCKNDKEAELVGIEWCAAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A7G9WEI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caproicibacterium amylolyticum|TrEMBL
MKINELLKSGHITVSCEIFPPKKGIGLTHAREVVQEIAALNPAFVSVTYGVGGTNCDNSV
ELAAEVEKTGVPALSHLTCVSANKEEVRAVARRFAENGVENILALRGDIPQDGTFPGEGQ
YRHACELIADLKAMGDFCIGGACYPEGHVESASKAEDLQHLKEKADAGCDFFTSQMFFDN
DLFYNFLYRALSVGIRVPILAGIMPVTNAKQIKRSVELSGTYLPQRFVSLVDRFGDNPAA
MKQAGIAYATEQIIDLISNGVEHIHIYTMNKPEIAAQIFSNLSDIIADYAD
>A0A8H5FVH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetrapyrgos nigripes|TrEMBL
MKITQKISQCDKDNRVWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTAEMVKTCQGLIGIETCMHLTCTNMPKEKVDIALREAKISGCRNVLALRGDPPMGKEE
WEAVEGGFVHGVDLVRHIRREYGDYFDIAVAGFPQHMLLPPEERDREMKWLKEKIDAGVN
FIFTQMFYDVEIFIDWVKAVRAVGITIPIVPGIAPVQTWNGFQRATSLANIAIPQIFMEA
LEPHKNNDEKVREIGTKLVADMCRRILKEDLGIKGLHFYTMNLEKATKMLLEELNLVPRV
ETLKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGDLD
GYGVRIKQTKEEALKLWGEPTSVSEVTELFAQFCLGKLSALPWSDQAPASETFVISEKLA
RMNRLGFITINSQPAVDGARSNDEKFGWGPSNGYVYQKAYLEFFVNPALLSLLLAQIERD
SQITYYVINKQGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAYELGQQ
WAKVYDSDSTSRKVISDLMNTCYLVNVVHNDFRDPDAIFRPFFKAGEEYLASLKTTPAVT
VNGY
>A0A7R6SQU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Isorropodon fossajaponicum endosymbiont JTNG4|TrEMBL
MKISFEFFPPRTNQGKEKLIQVRQSLSVVSPEYFSTTFGAGGTTQDVTLEAVLDIQKNDN
IPAAPHLSCIGSEKSNIVELLDKYKSANINRIIALRGDIPSGVRDIGDFHYANELVEFIR
SEYNDHFHIEVAAYPEMHPQAKNIASDLSHFVNKIKAGANGAITQYFYNADAYFRFKDDV
QKLGIDIPITPGIMPITNYTQLLNFSNMCGAQIPKWILERLKLYENDLESLSGFGFDVVA
NLCQTLKSQGVDSFHFYSMNRANPSLKLAKSII
>A0A5C0U8Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MSKKVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLV
>A0A1U8QYB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)|TrEMBL
MHIKEKLAQNEAAGKIGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQERVDAALQAAYKAGCTNILALRGDPPREKEV
WEAADGGFRYAKDLVKYIREKYGNHFCIGVGGYPEGADDNSDVDQLIDHLKEKVDAGSSF
IVTQMFYDTDNFIKWVEKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKTHIPPDWLEAL
EPVKNDDAAVKQVGKRLIADMCRRLIASGIKHLHFYTMNLAQSTQLVLEELELTPTAEAP
IPRPLPWRPSLGLNRREEDVRPIFWRNRNSSYIARTAIWDEFPNGRWTDSRSPAFGELEL
YGVGLKGTNEQNIKLWGEPNSLRDLAEVFVRFLEGNLDRLPWSDSPITPETSAIKDALVE
LNRRGFFTINSQPAVNGVKSSHPVFGWGPKNGFVYQKAYLELLVPPYVIDELIARIEANE
DLTYHAVTKKGELRTNTRDSPNALTWGIFAGREVVQPTIVETVSFLAWKDEAYQLGEDWA
KCHEASSPTRKLLQGIMDSWYLVNIVNNDFHNTYDLFELFKDLNVKDLELEISGGITEDK
AHHNGTANGATNGTTSNGTAAEQPVKN
>S3B5D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HPH0547|TrEMBL
MAIGISAPRTERPPTVRDKLASGEKSFSFEFFAPKTPKGERTLWDALRRIEAVSPTFVSV
TYGAGGSSREGTVRNTERIANETTLTPVAHLTAVNHSRAELRNVIGQYANAGIRNVLALR
GDPPGDPLGEWVRHPEGIDYASELVELIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVN
KCRAGADYAITQMFFRAEDYLRLRDRVTAAGCDTPIIPEIMPVTNVKQIERFAQLSNATL
PDEMIERLRAVEDDPAAVRSVGIEYATQMCARLMAEGVPGLHFITLNHSTATLEIHQNLG
LRERA
>A0A1K1LT80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotellaceae bacterium HUN156|TrEMBL
MSILKLDATRRFSFEVLPPLKGAGTEKLFADIDKLREFDPAYINITTHHSEFVYKELENG
QYERQRIRRRPGTVAIAAAIQQKYGIPVQPHVICSGATIEDIEYELLDLQFLGISDLLLL
RGDKAKEDSRFTPTPGGHAHTTDLIRQVARFNEGFFADGTPIKHPGQKFDYGVACYPEKH
EEAPNMEMDMQYLKEKQELGAQYAVTQLFFDNQKYFDFVKKAREMGITIPIIPGIKPLAK
LTQLTVVPKTFHCDIPEALAKEIVKCKTDEDAKQLGIEWTTAQCQELYANGINNIHFYTV
SAVDSVAEVAKKLL
>A0A419EZL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Abyssubacteria bacterium SURF_17|TrEMBL
MDLLIEVETPLLWDVETYIEGLANLESFPTIVLAENGGVSAIAIGEALKGKTDKEVFIKI
TCRDRNRIALHSDLLTAAAKGLTNVVLAEGGHPVQTRFPAAKPVYELDSLLLLKMMRQAN
PSFGKDLVVALGSLPWKIAVCIGGATAADMSRAEKLHAAGADLFFVASLEAVKPVRRLTD
KPIFVSMYAENVSNLGEMLSTVESSGAQGMNLVLKALDKVIDGSIIRK
>A6NZH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoflavonifractor capillosus ATCC 29799|TrEMBL
MKIIDILSQDKVTLSFEVFPPKTSDSYESVAKATQEIAALKPDFMSVTYGAGGGTSDYTV
GIAAGIRDKYGVEPLAHLTCASSTREHVHQVLGKLKESGISNVLALRGDIPEGGAPAHDY
HHAAELVREIKASGDFCVGGACYPEGHPESPTKASDIDYLKAKVEAGCEFLTTQMFFDNN
ILYNFLYRIREKGITVPVVAGIMPVTNGKQMARICKLSGTYLPEKFKAIVDKFGENPAAM
RQAGVAYAAGQIIDLIANGVNHIHIYSMNKPEIAAGIQASLSEVLK
>A0A1Q4YN12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TSRI0281|TrEMBL
MALGTPSTRTDRARTVRDLLATGTTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRSGTVRATQQIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHTRGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFNPDDYLRMRDRVVAAGCDTPIIPEVMPLTSVKQLERFAQLSNATL
PASLKERILAVKDDPAAVRSIGIEFATKFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A656TWM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL S-444|TrEMBL
MALGTASTRTDRARTVRDLLASGSPSYSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSV
TYGAGGSTRGGTVKATQQIAADTTLTPVAHLTAVDHSIAELRNVIGQFADAGIRNMLAVR
GDPPGDPMGPWLAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSAGKAGCETPIIPEVMPVVGIKQLDRLPQLSNAVF
PAAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQRA
>A0A1F9MDK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYD12_FULL_50_9|TrEMBL
MLVKDILDSTKISFSFEFFPPKLDSDWDNLFQTIADLMPLKPTCVSVTYGAGGSTRDRTH
QLIVRIKQQTDLTVVSHLTCVGSSRDEIRMILDNYDQSGIENILALRGDLPRGQAQWLQP
EKGFAFAAELVAFIKKYFPHMGIGVAGFPEGHPETQNRLKEIDFLKAKVDAGADYIVSQL
FFENHDFFDFCERCELAGIRVPILAGIMPITTRQGMVRMAELAAGARLPASLLKAISRAT
TDDYVEKVGVHWATEQVRDLIDHNVRGIHFYTLNKARATLKIYESLGVTDSDQLTG
>A0A395J0Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monilinia fructigena|TrEMBL
MEKITEKIAALPTDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALKPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRAVDEKNGDTPTIDWEFEWAIDLHIQKDTQMKDIQKDKVLNMICHTWLKKVQAGADFIM
TQLFFDVDAYDKFEQILRDHPSGAFKNIPIIPATRNFLQNIITRLDEVRGDDEMVKKVGV
DILSEMVEHLKSTKSQYLGPRGFHFYTLNLEKAVSFILERTDLIPDADAVAALEPELVPT
IPDIADLLSVYSGSHKRSSRRRSSVGSDPYDRIIITAPQISNPSFEATAKEAGVPAEAVN
SRANTLAISEGEGSLGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGH
PSSRADITDIFIRHLEGQLTAIPWSEEGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGL
KSSDPIFGWGPKNGFVFQKAFVELFLPTSSWETLQAKLTSPALCDTVSFYASNPKGDFVS
SDETIGSTNAVTWGAFPGKEIITPTIIEEVSFQGVGGRSFWDLG
>A0A1L9NWS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktotalea frisia|TrEMBL
MSTPTVSFEFFPPQNLEASFRLWETVQTLAPLDPSFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNATKEETLAIAADFAKAGVKEIVALRGDAPKGEAKFTPCKDGFENSV
ELIEALSATGDFKIRVGAYPDRHPEAPSARADIDWLKAKIDAGASEAITQFFFEADTFLR
FRDDCVRAGIDALIIPGILPIENWKGTRNFAKRCGTKVPTWLEDAFEKAERDGRSDLLAT
AICTELCSDLMAEGVDALHFYTLNRPELTRDVCHALGVVPRVELQNVA
>Q5B0P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)|TrEMBL
MHIKEKLAQNEAAGKIGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQERVDAALQAAYKAGCTNILALRGDPPREKEV
WEAADGGFRYAKDLVKYIREKYGNHFCIGVGGYPEGADDNSDVDQLIDHLKEKVDAGSSF
IVTQMFYDTDNFIKWVEKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKTHIPPDWLEAL
EPVKNDDAAVKQVGKRLIADMCRRLIASGIKHLHFYTMNLAQSTQLVLEELELTPTAEAP
IPRPLPWRPSLGLNRREEDVRPIFWRNRNSSYIARTAIWDEFPNGRWTDSRSPAFGELEL
YGVGLKGTNEQNIKLWGEPNSLRDLAEVFVRFLEGNLDRLPWSDSPITPETSAIKDALVE
LNRRGFFTINSQPAVNGVKSSHPVFGWGPKNGFVYQKAYLELLVPPYVIDELIARIEANE
DLTYHAVTKKGELRTNTRDSPNALTWGIFAGREVVQPTIVETVSFLAWKDEAYQLGEDWA
KCHEASSPTRKLLQGIMDSWYLVNIVNNDFHNTYDLFELFKDLNVKDLELEISGGITEDK
AHHNGTANGATNGTTSNGTAAEQPVKN
>J4KUF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. FOBRC14|TrEMBL
MLIQKIKNNEAGILLYGLTPPKENLTGEETAAIAAKQIARLEGQNIDGIVLYDLQDESSR
TNEERPFEFIKTTPPETYYETYLKKHFKAVIYKAVGKYDEPEFCEFLRHQQEDFICVFVG
ASSKSQEVKLRLDEAYALKAKFAPNITLGGICIPERHASKLDEHLKVAHKSEKGCEFFIT
QAVYNLENAKKFIDDYAKLEGKKCPIIFTFTPCGSAKTLLFMKWLGINIPPNFEERLNAS
ENILQTSLNLCLEIFNFLYKYGLAKGISVGANVESVSNRKVEIEASITLLKQIQEIIAKT
NTAYHWIGAGV
>A0A0R2XP91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutaceae bacterium BACL24 MAG-120322-bin51|TrEMBL
MKTLSIKQRLANNHPLFSVEFFPPKSDDTAQQLLHTAERIQAYRPDFVSITYGAGGSTRS
RTLNYARKLHEDYGYAVMPHLTCVGHSREELKQIIAEFKSAGLKQIMALRGDPPKGETNF
TPHPDGLRYANELVQLIREVYPECDLGVAGYPEKHPEAPSLEIDLLNLKRKVDAGATFVT
TQLFFDNSAYFEFVEKCRRAGITVPVLPGLMSITSYKQALRFCEMCGTSIPVALNQQLIA
AGEDQAAVEAIGIEWSYQQAHELLEKGAPGIHLYILNRAGPAIALMKKLQRAGFYK
>A0A0M9GEV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fuscovaginae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASHNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPSAPHLSCVGDSKNDLRGLLTQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDIQHFVRKANAGADSAITQYFFNADSYFY
FVDRVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSQSIQAFG
EQVVTQMCERLLQGGAPGLHFYTLNLAEPSLAVWNNLKLPR
>A0A7K0DIV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia aurantia|TrEMBL
MRAHGRITPSVTGRHSRTSPVTAARSVVGRLGPRPDGTVPFSIEFNPPRDAAGEDRLWRA
AREFECMHPAFASVTYGAGGSTRDRTVRLTGRLAQETTLLTVAHLTAVDHSIAELRSIVG
AYADAGIHNLLVLRGDPPGDPLGEWHRHPEGVEYAEELVRLVRGLGNFHVGVASFPRGHH
RSPDLDYDTRHLIAKLRAGAEYSITQMFFEADDYLRLRDRVAAADPVEGAKPIIPELMPI
TSLRTVQRAEELSGRPLPAALRERLERAAGNDPEGNRAAVRAVGIEIATELGQRLIAEGA
PCLHFITLNFAKATGEVLANLGYTVRPAAVGA
>A0A7K7QZI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poecile atricapillus|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRSYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A2D3P7M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium pseudoperiodonticum|TrEMBL
MKIADIYKGKSLTTSFEVFPPNDKVGLDQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIADRIKNQNGVESVAHLTCIGAKKEEIDKVLEDLEKHNIENILALRGDYPVDRKLEVGD
FSYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A2D3NT35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium pseudoperiodonticum|TrEMBL
MKIADIYKGKSLTTSFEVFPPNDKVGLDQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIADRIKNQNGVESVAHLTCIGAKKEEIDKVLEDLEKHNIENILALRGDYPVDRELEVGD
FSYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A844FR86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sharpea porci|TrEMBL
MKIIDILNQDKVTLSFEVFPPKLTKNYDDVAFKAKEIAKLHPDFMSVTYGAGGGTSEYTL
NIAKEIKEQENVEVMAHLTCVSSSKAHVHSMINRLKENHIENIMALRGDIPVGGSQFHDY
QHASELISEIKASGDFCIGAACYPEGHPEASNKDMDIKNLKKKVDAGADFLTTQMFFDNN
VFYNFLFRAREAGIDVPIVAGIMPITRGIQVKRARELSGCSMPQRFISMVDKFGDNDEAM
KQAGIIYASEQIIDLIASGIQHIHVYSMNKPDVAKAIMENVSEIIK
>A0A1E9A782|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC034E03|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQDLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKRKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQSLG
>A0A557SGF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denitromonas halophilus|TrEMBL
MNPTPFSIEFFPPQTPAGVDKLRGTRAQLAQLQPEFFSVTYGAGGSTQERTFETVFEIQA
EGLAAAPHLSCVGATGDSIRDILKRYQDKGIRRIVALRGDLPSGAVEAGELRYANELVEF
IRRETGDWFSIEVAAYPEYHPQARTAQSDLAAFKRKVDAGANSAITQYFYNLDAYLHFRD
ECVAMGIEIPIVPGIMPIVSFSKLARFSDACGAEIPRWMRRKFESYGDDTDSIKAFGLDV
VTDLTARLIEEGAPGLHFYCMNMAGPTSTIVERLGLKA
>A0A2U1CQ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas noertemannii|TrEMBL
MSSLVSLEFFPPRDNAAQEKLIRSAKQLQALQPGYVSVTFGAGGSTRAGTADAVAIMQKL
GFDAAPHLSCIGASAQDLADILQAYKRQGVRRIVALRGDLPSGMGGDTGEFHYASQLVRF
IRETTGDWFHIEVAAYPEMHPQARNAAADLGHFVEKVQAGANSAITQYFFNADAYFSFVE
QAAARGVGVPIVPGIMPITNSAQLLRFSDMCGAEVPRWIRQRLAEFGDDKASIRAFGEEV
VSRLCQTLLDQGAPGLHFYTLNNADTTLAITRNLNISVEAA
>A0A4D6Y1C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MHIFSEYYQDIVKQKRENIRNFAKCSFEFFPPKNSILEKNLFSSVEKLSTLKPRFFSVTY
GANSGEREKTYKYVKKIYRKTGITTAAHLTCVDSTPDELKKIAENYWENGIKSIVALRGD
TLTQNLKHKMYASDLVILLKKIANFDISVAAYPELHPESKNSEFDIVSLKRKVDAGASRA
ITQFFFNVEKYLYFRDNCLKHNINIEIIPGILPIYNFKQLQRFSSMTNVKIPNWMFEIFN
GLDDDLITQKNIGSSIAIDMVKTLSREGVKNFHFYTLNQSDTVYTVCHVLGL
>A0A2T5Q7K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter oleivorans|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLRIVHQELQLLNPDFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKTQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIRVHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A3E3DWN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerofustis stercorihominis|TrEMBL
MKITEILKQDKPTLSFEVFPPKNEVNYKDVEKATGEIAKLKPDFMSITYGAGGGTSSYTV
NIAKEIQKEYAVPTLSHLTCMCSSKEDIKAQLKLLKDNDIENVLALRGDIPSDKSLMDKS
EYTHAVELIRDIKESGDFCIGGACYPDGHVECKHKADDIYFLKEKVDAGLDFLTTQMFFD
NNVLYNFLYRIREIGITVPVFAGIMPVTNGKQIKRITELSGTYLPTRFKAIVDKFGDDPA
AMKQAGIAYATEQIIDLLANDVRGIHVYSMNKPEIAEGIKNNLSNIL
>V7BMY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaseolus vulgaris|TrEMBL
MKIIDKIHEAAADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANKMQNIVCVDTMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVKHIRAKYGDYFGITIAGYPEAHPDVIGSDGLATAEGYQKDLEYL
KSKVDAGADLIVTQLFYDTDTFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPADIMSALEPIKDNEEAVKSYGVHLGTEMCKKILSHGIKNLGLIEESKISRSLPWRRP
TNVFRVKEDVRPIFWSNRPKSYISRTIGWDQYPHGRWGDSCNPSYGALTDYQFMRPRSRD
KKLIEEWVVPLKSIEDIYERFKMYCIGKLRSNPWSELDGLQPETKIINEQLERINSKGFL
TINSQPAVNGEKSDSPTVGWGGSGGYVYQKAYVEFFCSKEKLDTLVDKCKDRTSLTYMAV
NKEGSWKSNVGQTDVNAVTWGVFPAKEIKQPTIVDPVSFNVWKDEAFEIWSRGWASLYPE
GDASRKLVEEVGGSYFLVSLVDNDYINGDLFAVFADF
>A0A1H8MEB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. OK283|TrEMBL
MKITEHIANAKGKTLFSFELIPPLKGQSIQGIYDAIDPLMEFKPPFIDVTSLREDFIYKQ
HDNGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLVDLQFLGIEN
VLVLRGDARRGDASFVPTPNGHNYATDLLQQVVNMNNGIYLHEHNDDSLKTDFCIGIAGY
PEKHFEAPNLKTDFKYLKQKVDMGANFIVTQMFFDNQKYFDFVNNCRANGINVPIIPGLK
PVTNSKQLIGLAKTFHIDMPEDLCDAVNGCKSEKDVRDIGVEWMINQCRELMAFGVPVLH
FYTMSNAGPTKRIAEAIF
>A0A5K6CQJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain AB307-0294)|TrEMBL
MSHLSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKVKAGADFIITQLGYDIEAL
KQAKSFLTKHNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQVGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVT
TSKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A8H6C963|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Letharia lupina|TrEMBL
MEKITDKIAALSNDANYFSLEFFPPKTQIGFSNLQTRLERMSSALRPLFVTVTWGAGGCT
SSRSLELAEICQRQLGLTTCLHLTCTNMKRKVVDEALEEAKVLGVRNILALRGDPPREEE
YRLEDEAENGKDEDDSNEDFTWAIDLVRYIRRVHGDYFCIGVAGYPEGHADQSHPTDQDP
LHDLPYLIDKTKAGADFIMTQLFYDVEAYSKYEKMLREHESGIFAQIPIIPGLMPLQSYE
ILMRTTKLAHAKVPLELLHKLQGVKGDDEAVKQVGVEAIHDVVESIREVKAKGPRGFHFY
TLNLEKAVSSLLDRCNLIPPDPDDNNVSAIDDVSILFNGNAAHHRALSSASSSAAAQLTT
NSHRSSSPARFIPPNSNPLSREATWDDFPNGRFGDARSPAFNPPLTYSPTSLTISPAQAL
SLWSTPTTPEEITHLFISHLAGQTPKQLPWSESATLSPETALITSELTQLTRLKGYWTIA
SQPAVDGLPSIHSIHGWGPPGGFVFQKAFVEFFVPASTFHTTLRPHLDRLRKEGEISYYA
GNAAGEFQSSESSDAVHAVTWGSFAGKEIATATMVEEVSFRAWVEEAFGIWGEWGRCVGE
AARRGRVEKARQSRGFLRRIGKDVWLVNVIGHGYREGGRLWEVLIEA
>E6LQ59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoanaerobaculum saburreum DSM 3986|TrEMBL
MENIRDYLKNNILLFDGAMGTYYDELTDDGIGCELANIKNPELIKGIHNEYIEAGAKAIL
TNTFAVGIDVFNGDRKLQKEVIVAGIDIANDAAKDRAYVFADIGPIHMSRNELVFEEYKV
LIDIFLEKGIKNFLFETQSNTSGMVLSAGYIKGKCSDAFIAASFAVMPDGYSSEGYQYKA
LFAEVTDSGLFDAVGLNCVSGANHMAKLLKGVDTKGLYLFAKPNAGYPVVRDDRVYYSSL
ANYFANQIEDILEMGVNIVGGCCGTTPKHIELLKKSMSGKLIKPRRAIKSEKNTTQNIRL
NRFKNKLESGQKAIAVELDSPIDTNVNKFIENAKKLKLAGADIVTIADNPIARARMDSCL
LACKVRNELDFDVLPHMTCRDRNVNASRGLLLGANAMGVDNVLVITGDPIPNAQRDEIRS
VFEFNSVKFANFIKSLNDEVFESPMNICAALNVNSRNFSAELKKAKRKQENGVEVLFTQP
VLTKRAIENLKEARENLDVKIMGGIIPIVSERNARYMQSEVNGIYITDDIVEKYIGKERE
EAEEIALSMSKEIANEIYDLVDGYYLITVLNRVSLMERLIKTVKEVCEKR
>F3ZX27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mahella australiensis (strain DSM 15567 / CIP 107919 / 50-1 BON)|TrEMBL
MRGEKDFLTALKYKTLLCDGAMGTMLRERGADSEACLEYMNISQPDMVLTLHKDYIGAGA
DIIETNTFGANRFKLAIYGLEDRVADINRQAVKLARQAAGNNIWVLGAVGPIGLPLIPVN
EKDRGDIYEAYGEQIEALCCEGVDAIIAETMGSTLEAEMAIKAAKDAADIPVICQFSLLP
DGFDSSGESLQSVAEFLKHCNADVVGLNCGSGPRDMVEFMKFIAEYTDGSKFLSIQPNAG
FAYYAQGRLQYKAKADYFASYVKDYIGLKVNIIGGCCGTTPQHIAAMRSVLNENTSLETS
NMIAMEPGTITAEVSRSELTQAGIAMAGNILEKIKQKFVVTVEMDPPKGTDIEKALAGAR
ALKSCGVDAVNIADSPMARVRVSPIALAARIKQEVGLDAILHFTCRDRNLIGIQSELIGA
AVLGINNVLALTGDPPSIGDHPKATGVFDITSEGLVYILGALNQGRDYMGNVLEGSTNFA
IGVAFNPNADDLKAELEKLDKKIENGANFIQTQPIYDMQTVEKMVKNIADYNIPVLMGVL
PLRSYKHAEFLHNEVPGITIPLDIRQRMKNAGDNALDEGVAIAAELIKQCRGMVSGVYIM
PPFGRYDMVEKIMAEIAW
>A0A0J6JLH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas taetrolens|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLMNTARQLAAYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYRAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDINNFVRKARAGADSAITQYFFNADSYFR
FVERVEQAGVTIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A249N7H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus rhamnosus DSM 14870|TrEMBL
MRPILNTLDAVKAADPDFVSVTFGASGNKPHMGTLEVAKLIKNEFNLEPVAHLPAAQLTR
AQVDAELRGFQEAGIDNILALRGDIPKSGRVSEDFPYACNLIEHIHQVGDFDVVGACYPE
KHPESPDVVSDIRHLKEKVDAGASQLISQLFFDNQVFYQFRERAALAGINVPIEAGIMPV
INEHQIERMATMAGVHLPPKFVAMMQHFSGNKEAMRDAGIAYAIDQIIDLLVHGVDGIHI
YTMDNPVVKRIAAATQTIRNA
>M7CEH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morganella morganii SC01|TrEMBL
MSFLHIDQHEALNQNLAELAGRVAVSFEFFPPGTPEMEKTLWQSIERLSVLKPKFVSVTY
GANSGERDRTHSVIKSIKEKTGLIAVPHLTCIDATRDELKTIARDYWDNGIRHIVALRGD
LPDSSSKPDMYAADLVGLLKSVADFDISVAAYPEVHPEARSAQSDLINLKKKIDAGADRA
ITQFFFDVSTYLRFRDRCAAAGIDVEIVPGILPVSNFRQLQRFAGMTNVRIPSWLGTMFE
GLDDDPESRKLVGASVAMEMVKLLSREGVKDFHFYTLNRAELTYAICHTLGVRPAACVA
>A0A327JJ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobium orientis|TrEMBL
MNAHFTPTGAVVDETVSAASSARPVAETTRDVIRRLAQNFSLEIAPVAASKIAFFNEVLP
EKSPVFVPVLPGTALADNVALVARLAQDGMRPVPHIAARRLSSYGELDDALSRFRETGGI
EDVLLIAGDPAKAAGPFRSSLDVLESGLLERHEISRVFVAGHPEPNPDIPVATARDFLME
KNVWARETGTVVEVVTQFSFSSRAILSWEREMRAAGNELPIRVGLAGPTKPATLLKFAAL
CGVKASAGFAARAGLKLTKMASERAPDDVISDLAAAMLSDADSRISGIHLFTFGGFAKAA
RWITSVADDRFMPNAKLTGFSVEA
>A0A2H0AUZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG23_combo_of_CG06-09_8_20_14_all_45_10|TrEMBL
MAKSLFDEKLNSGKFLVTTEIGPPKGTDVSEMIHHIELLGDKVDALNVTDHQSSVMRFPS
LGGCLLIKEHGGEPILQMTTRDRNRLALQADLLLAYSRGIRNVLCLTGDSLDVGDHKEAK
PVFDLDSVQLIRMIRTMESGKDLGGNDLKGKPEFCIGASVHPAADFIEPQLIKFEKKVAA
GAEFFQTQGIFDLDTIRRFMQYARQFNVKILAGVIVLASARMARYMNDNVPGIIVPQETI
DELASVEKGKALQKGIEIAAHLIKTIKEENLCHGVHIMAVGRESIVPDILEAAGLLTKEN
KK
>A0A1Y5DZE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium 46_93_T64|TrEMBL
MSILKFDEHEAPLPPEPGHSSRGRLERILRAGEFAVTAELNPPDSADPNDVFERGAIFDG
WVDGINATDGSGANCHMSSVGICALLTRVGYSPIMQISCRDHNRIAIQGNVLGAAAMGVN
NILCLTGDGVQAGDQPGAKPVFDLDCMSLLRTIRQMRDEGKLLSGRKLTSPPQVFLGAAI
NPFAPPYDFRPLRLAKKIEAGAQFAQSQYCFDIPMLETYMDRVRDMGLDEKCFILAGVGP
LASARAAKWIRSNVPGIHIPDSIIERLEGADDQKLEGKKIAIEVLQQVREMKGISGAHVM
AYRQEELVAEIVHESGVLKGRKPWTREANPGFEAVAEAVENTIEHIGEAIEPSAAVAAAS
D
>A0A447P2J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Sanjuan|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>X8GRT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium sp. CM22|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEIGD
FNYAKDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>C2L0W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oribacterium sinus F0268|TrEMBL
MSIVDLFQEKTVFSFEVFPPRRNSPVETIYDTLDELRDLKPDFISVTYGAGGGKNNQSTI
PIAEHIKKVCEVPSVVHFPCINLTKQDVLEKIEELKTAGIKNILALRGDIPEGEENRGDF
RYASDLIAFLKEHGNFHISAACYPEGHIESADRVEDIRYLKNKVDAGAENLISQLFFENK
QFYIFQERCALAGIDVPIEAGIMPVINSRQVLKMASLCGVNVPKKFQRILDKYADNPIAM
RDAGIAYAVDQIVDLVTHGVDGVHLYTMNNPYIARKIYKATHSLFESTQKGNPGGSSASA
>A0A2T5MGW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophobium rhamnosiphilum|TrEMBL
MTQEVSFSFELFPPRTPEGAAKLPAVIEKLAALKPQYFSVTYGAGGSEQDGTYETVMRVI
KQTGIEGAPHLTCVGSTRENIKSLLDKYRAAGIRRIVALRGDLPATAMDTSAPGELRYAN
ELVSFIRELHGDYFHLEVAAYPETHPQAPSPEADFENFRRKVEAGASVAVSQYFYNADSY
FDFVERCQKANIKIPIVAGIMPITNHAQLTRFSAACGAEIPRWVRLRLEQYQDDKQALQD
FGLDVVTRLSRTLLDNGCPGIHFYTLNQSEATLRLWKNLGLPVPVTSANT
>A0A1H0MUD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus singaporensis|TrEMBL
MKTESKLEKVLKAGHLAVTGECGPPRGAKPEEVIAKSKHLEGIVDAINVTDNQTAMVRMS
SLAASVLIKQQGLNPLLQVTSRDRNRLAMQADIIGAYSLGIDNMLCLSGDHTKFGDHPSA
MNVHDIDSIQMIQMVKDMRDKGIFQGGAELKGAPKMFIGAAANPFADPFELRVMRLEKKI
EAGADFIQTQCIFNVDKFATWMEGVCKRGLHKRCYILAGVTPIKSLGAAKYMANRVPGMD
VPKEIVERMASVPKEKQAEEGVTICVETIEKLKQIEGVAGFHIMAIEWEEIVKEICERAG
LLPRPQV
>B1YR55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia ambifaria (strain MC40-6)|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRADLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFTQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNAASATRTICERLAM
>A0A089KZJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL R7-0331|TrEMBL
MKPDLRSAWKNNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYIEAGAVL
LESNTYSANYDKLAKFGLEGKVEEINRAGVRIARKAAGEAGYVVGAVGSIRAGKRANLSA
AELKRFYAQQFSALLEEQPDGIMLETFYDVEELHLALKSVRKLSSLPVICQLAVDETART
LDGLTLPEAFRILEQDGADVIGFNCRTGPNGIKRALRTLQGSLALPVSVYPNAGIADYVD
GQYRYGATPEYFGQMAPVFADMGSRIIGGCCGTTPQHIAEISAALRGYTAQPLAEPAVTR
KAEQIVVHEHLDEGADQNGREPNLVDLVKERHTVIVELDPPRDLDITKFMKGAEALRRAG
ADALTLADNSLAVTRMSNMALGSLVQARTGLRPLVHVACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIRQLNDGIAFSGKPLKQKAKFVIGAAFN
PNVKHLDKAVQRLEKKIASGADYIMTQPVYDPKLISEIAAATRHLEIPIFIGVMPLASGR
NAEYLHNEVPGIQLSDEVRRRMQGLEGEAGRAEGVAIAKELLDAATAHFNGIYLMTPFMF
YEMSVQLLDYIWAKQGRKLSPLFR
>A0A7C8KQV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gracilibacillus oryzae|TrEMBL
MSTLRKELQEKILIADGAIGTLLYAHGLEQCFEAFNLSKQEEVLQVHRSYIEAGADIIQT
NTYGANYIKLARYGLEDQVHEINAEAVKIAKKAANPDTFVLGTIGGIRGIQKLITSKKEI
IRSFKEQLFPLLLEGVDGILLETYYDLEELQTVLEIVRKETDLPVITNVSMHEPGILENG
TLLTDAFYQLEDSGADVVGVNCRLGPHHMIKALEAVPLLKYAYLSAFPNASLPAYENGKL
VYSDKTEYFKQCAIKFRDQGVRLMGGCCGTTPEHIQALKEGINGLEPITEKTVKENPLIV
TQSEPQQETQQPGILEKVNERHTVIVELDAPKHLEIDEFMEGVKQLNDAGADAITLADNS
LATPRISNFAMAMKMKELNLNAQPLIHLTCRDRNLIGLQAHLMGLHTIGFHEILAITGDP
TRIGGFPGASSVFDVTSFELIRLIKQCNQGLSFSGAPLRKKTNFKVAAAFNPNVANLEKA
VKRMEKKIDHGADYFLTQPVFNHEQIIALHRETKHLSTPIFLGIMPLVSHKNAEFLHHEV
PGMKLSDEVRARMQAQTNRHDAVQEGIQIAKELIDTAINYFNGIYLITPFMRYQITTELT
KYIIKVSNKKKILH
>A0A2H3CP22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armillaria solidipes|TrEMBL
MKIIDKITAHDGPHPFYFFEFFPPRTDQGFENLLSRISRLSNLRPMAVSITWGAGGSTRD
RSLDLAGLSQTEYNIDTILHLTCTNMMQGMVDDALAAAKSRKIENILALRGDPPRGKEEW
IPIDPRFQRGVDLVSYIRSSPQFSSQFCVGVAAYPDRHPDSLHDEDTEIEYLKVKVDAGA
EFIVTQLFYDVDQFLRWEKKVRAKGISVPIIPGIMPIQTYSSFLRLIKLCGTSVPSFIMS
DLDPIKHDDQFVKDYGVKLAVSMIRRLTSEGKVPGVHFSTLNLEKSVQRVLETLQWAGAA
PPTYNKLIEQDTHDDRSVTPSSASRAAKYGLATISTTDGEAGSGELNNAATWDDFPNGRF
GDFKSPAYGDQDPYGNVGTITLGPWGHPQTINDLTTIFLDHLHSKIPTTPFSPTPLSPES
LTILPHLEKLTKRGWWTVGSQPAVDGAPSSDEVFGWGPRAGFVFQKGFVEFFCTEDDLDI
IEKKVTDNGKGWVHWFAGNAKGDYRGNIPDDGRNAVTWGVFTGQEIIQTTIIERESFLSW
KDEAFSIWSEWASHYRPGSEERSLLDSVKKERWLVSITHHDYKNTEALWTFLSDIIETTD
M
>A0A6B2SV33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID10115|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTFSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGDWIAHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSPDWESDTRHFID
KCRAGADYAITQMFFDPEEYLRLRDRVEAAGCATPIIPEMMPVTNVRQLDRLPQLSNAVF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHQA
>A0A550GC39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ALS1279|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFG
EQVITEMCERLLQDGAPGLHFYSMNLAGPSLAIWNNLKLSR
>A0A5C8E2Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira aalborgi|TrEMBL
MNSVENFINKLENEKEFTFTLEVTPQAKSDLGYLVEKIKSSNIEKYIDAFIIPDSPFANL
KISPILSSLQLSQRLKTEKPFIITQTMRDKNSIALQNDLIGANYFDIRMVLALTGDPVVN
GNQKQAKGVFEGNSELLIKIIKNLNEGKSAGNFIFKEPLKKIYPFCSINSYSKNDEMLKV
RLSKKTASGVKAIFTQPIYEVETLKKFLNWIDEMPLKEMKLKEKPILFPGFFPVLSYKTA
YFIYYKLPGAYIPEEWLNKLKDASEKSAEEEKKVAFELSSNLFKDMLSVCKKMHIMSMNN
YDFVADLLKDI
>Q8EY55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A4S1DZG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavivirga rizhaonensis|TrEMBL
MKVTDHIKKADGKTLFSFEIIPPQKGRNIQELYNNIDPLMEFKPPFIDVTTSREQYIYID
KGDGLLDRKITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIEN
VMALRGDAMSHQKYFEPSKGGNHYATDLVAQIQNLNCGKYLHDVVETNHKSDFCIGVAGY
PEKHMEAPSIQADLRRLKEKVDAGADYVVTQMFFDNKKYFEFVDKAKKAGINIPIIPGIK
PLAVKRHLQILPQVFKIDLPEALVDEVEKCKDNKQVRQVGVEWAIKQSEELKKAGVPVLH
YYSMGKSDNIKAIASQLF
>A0A1V6IDT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium ADurb.Bin026|TrEMBL
MTTESNLEKVLKSGSFAVTSECGPPRGADTEAIRKKGAFLKGYVDGVNVTDNQTSVVRMS
SFSASLVLKEMGFDPVMQMVCRDRNRIAIQSDILGAAALGIHNLLCLSGDHQSFGDHPSA
KNVFDIDSIQLIQTVKRMRDDGKFLSGEQIKGRPDIFIGCVENPFADPFDIRALRLAKKA
AAGAQFVQTQCVFNVEKFSKWMEMVRDLGIHEKMYILAGITPFKSVGMARYMKTSVPGMD
VPEGLIKRLNDTPKDEVADEGIKICLEIIEQVRTIKGIAGIHIMAIEWEHKVPEIIEAAG
LYPRPS
>A0A257SQW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium 21-64-14|TrEMBL
MESQERHPAVYSFEFFPPKTQEGVAKLRGVRDRLARLEPRFFSVTFGAGGSTRERTFETV
TEIQRASGIEAAPHLSCIEATQDSVREILRRYQAEGISHIVALRGDLPSGSGSAGSRELR
YAADLVAFIRRETADHFFIEVAAYPEAHPQSRGARADLLNFKRKVEAGANSAITQYFYNA
DAYFRFVDECERLGIDLPIVPGIMPITNHVQLARFSDACGAEIPRWIRKRLEDFGEDKES
IRAFGVEVVTELCRRLLEAGAPGLHFYTLNQAVPSLAIWDNLGLGGRGPGSTGPGSDRGS
RPG
>A0A1Y1QWB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiothrix lacustris|TrEMBL
MTDDHQHDHVNHDDLIFSFEFFPPKTDKGAENLRAVRNELAALNPRFFSVTYGAGGSTQA
NTLNTVLEIQRDSGIEAAPHLSCVGSSAEQIREILDTYRNNGIKHIVALRGDLPSGSRDL
GQFRYANELVEFIRKETGDHFNIEVAAYPEMHPQAPNLKVDIDNFVRKVNAGANSAITQY
FFNADAYWHFVDECVKKGVEIPIVPGIMPITNYSQLARFSDMCGAEIPRWLRKQLETYAD
DVESIAKFGEEFISLLCENLLETGAPGLHFYTMNRVEPTMSIWKNIGLAD
>A0A6B3DXF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8499|TrEMBL
MNPLSTARTAVGALLLEDFSLEMTGKDVAKLEEARETIPQGTRINITFLGNEDLRMRLEA
SRAVKRLGFVPVPHLSARRLGSRAEFAEFLAALRAEGACDNVFAVGGDPARPKGPYEDSL
ALIESGLLQEHGVRHVGISGYPEGHPDIAADVLRAALRDKSAALRARRLDGGVITQFCFD
VDPVLAWLAQLREQGITLPVRIGVPGPAGVRRLMSYAARFGVGTSASIAKKYGLSITNLM
GTAGPDRFLHALAEGYDPARHGDIKIHFYTFGGLRATSEWIARFRKEHHV
>A0A6L3SZK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium soli|TrEMBL
MPASTYRASREGCRPIRVSFEFFPPKTEEMERTLWSSIERLAPLNPSFVSVTYGAGGSTR
ERTHNTVARMVRETNLKPAAHLTCVNATKDEVDEVVRAYWDAGVRHIVALRGDPADGVGS
AYAPHPGGYQQTCDLVAGIKRIGDFQVSVSGYPEKHPEATSLDADIDALKAKVDAGADRA
ITQFFFENDVYLRYVDRVRARGIDIPIVPGILPVQNFKQASNFARRTGASVPEWLAHRFE
GLDDDVDTRRLIAGAVAAEQVLDLVDRGIHDFHFYSMNRADLVYAICHLLGLRAEKPVVA
AERVAA
>A0A2D4BYY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pythium insidiosum|TrEMBL
MELLVWXAXLGCDDEQASDTETLSRLLYAFDSQAPSSPPPSAWQLQALNLMQALVTFSCG
LRERRRPDXSPSPSTSVARSGISVTLARRRVFIXEVXPQIXMSLXXDAADGDTELRDAHN
ALLHDLYDTFRLFFGSFHRRLDCLEQQTPETSAFPDGMALLRQLQSLRKQQRKXXIAREL
EQDEVHTRKDDGDAAAELQLXHXKTQIDALEAVAPTRRLWSDCHALFPTLLRSLVHAAAP
LNVFHELQGLTYFPMDETTFLAVQTFVNSLVAELDGVVHDVALFFKGNVLWRSMPSLRSL
HVLQRFLRLREQXGMTVDLWDXPXRQXDDRVASTLWMPRDYDDAFLPIWASKTAYAELTI
ARHQASSASASAASSSRRSLHRQSSSTLNALIADLVSQLDLSTXSASSPRQRQLKRXXSN
GNGSGSGRGGLFSFDKAEQLVLRRTQRFRANTACYRNRGFLTTSGYFLATWELAKNSDSD
TFWCPQVYALGDTDDATGRDDARRVIVWHEAELTLLLLVPSDDXVSLSLMERIETXLERL
DAARLAATIATRFHAMTTSHNAKREKAAATAAPPFVYLNRANLAFTAQHIPRLXKTRDDS
SXSLFPRPVGLWASYVPSHVLSIMASLNATIKSGQAAHGDVELSVKTMSDGWVVMRHTHS
TQRQLVVFLDTKSSCVPDVQXAIEELLQXQFGNVFFISLLSLLPASTDRPTMGKIIDAIL
ATYAGSSDGAASTSTSSSAGAGAARPTVSFEFFPAKTEDGVFNLLNRVEEMGFSLRPTFV
TLTWRSAFKDEKLWLRIGAHIQNEFQLDVLLHLTCHLPREELRRVLHAARAAGIRNILAL
RGDPPIGAERWKPVPDGLNNAVDLIRLIREEHGDYFCIACAGYPEVHTESWNHPDLPPSK
EARLLDLQRLKMKQDAGADFIITQFFFDTDNLLQWVKDCRELGISIPILPGYLPIQNYNS
FLKFTSWCKTRVPHDVLAALDKIKNDDAAVRRYGTELAIQTCKKILDAGIKSLHFYTMNL
ASTVTAVLDGLELIPARAQRDLPWQSTLRRTNSNGDRTEQVRPIFWSNRQASYIARTSAW
DEFPNGRWGDRASPAYGDLSEYYLAFKRPKVNRRELWGSPQSHEDVWQVFVRFIDGAVKQ
LPWCEQALSLESVVIKENLKWINAHGFLTINSQPRVNGAPSTDPSVGWGSPNGFVFQKAY
LEFFVSPRLLEKLLVAVKDYPHLSFHAMNRQGVEYTNAPPHSVTAVTWGVFPGQEIVQPT
VVDSDSFEAWKDEAFELWQTQWASAYDPTSTAFQVVQDVYNSYFLVNVVDNDYTNDESDI
FSIFTRIITDDMSKQDLRDRVIELEAKNEKLHETIAKFQTLHDELSQDLRDTHQQLASAR
DETQQLKTQLRQLQAHLALSTL
>A0A2S8RM44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. BL21I4N1|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVVDIAK
EGIEAAPHVSCIGSSKDSLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDMDNFVRKVKAGANSVITQYFFNADAYFRFVD
DAQKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTDLCERLLGAKVPGLHFYTLNGAAATKAICERLNA
>A0A1X6Y4G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudooceanicola marinus|TrEMBL
MSVPAVSFEFFPPKNLEASFRLWDTVQVLAPLMPRFVSVTYGAGGTTRELTRDAVGTLHK
NTGLNVAAHLTCVNATREETMQIVEGFATAGVTDIVALRGDPPKGEGQFTPTPGGFANSV
ELIEALSATGQFTLRVGAYPEKHPEAADQGADVDWLKRKLDAGASEALTQFFFEPETFLR
FRDRCAAAGITAPIVPGILPIENWKGLRRFAEACGTAIPTWLDDAFGKAIRDDRQDLLAT
ALCTEMCETLMSEGVDKLHFYTLNKPELTRDVCHAIGVTPRTKLEKVA
>A0A1V1WXS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium S7086C20|TrEMBL
MKSGSNLERILESGQFAVTAEAGPPKGTSSKVVQRKGELLKFCCDALNVTDNQTAIVRMS
SLSGCVLLKELGVEPILQMVVRDRNRLALQSDILGAAALGIGNMLCLSGDHQKFGNHPTA
KGVYDIDSIQFIRMVKEMRDEHKFLNGEEISGDVPLFIGAAANPFADPFEFRVTRLAKKI
RAGADFIQTQGIFDMSKFAEWMKGVRDRGLHKKTYILAGLIPIKSVGMARYMRNNVSGLD
VPQDVVDRMANSKDPKAEGVKICLETIEQLKEIEGIQGIHIMAVAWEDIVPRLVAQAGLM
PRPIV
>A0A448VP10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria weaveri|TrEMBL
MSNDKKQLSFEFFPTRTPEGRAKQVITRKQLSQYNPEFFSCTSGAGGSTKEGTLQAIQDI
LSEGIAAAPHLPCVGMQPSEIIELLDIYKEMGVRHIVALRGDIPSGVGAGMSGLRYANEL
VELIKNQYGNQFHVEVAAYPEYHPQARSAEDDINNFVRKAKAGADSAITQYFYNADSYFR
FVDDVQGRGVDIPIIPGIMPIASFSKLARFSDTCGAEIPRWLRLKLQSYADDTAAIKALA
LDVVTEMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>A0A1X9SWU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. RM6137|TrEMBL
MLKDKIKQGRSGIILYGLTPPKISLSEDKAKEIALKQLQRLEGIKIDGLVIYDLQDESSR
NSDNRTFEFVRTINPEIYAKDYLQNRYESVIYKAVGNYDKSEFRDFLLSHSNAISVFVGA
SSASDTPRLTLNEAYKMKKEIANTITLGGICIPERHMKKNNEDLRVASKRVKGCEFFITQ
AVYDIETAKKFLDDFAALGIKNTPIIFTFTPCGNEKTFEFMQWLGISISELSKRRIFNSS
DALENSVKLSLDMFEFLYKYGLTKGVSIGANVESISTRKVEIEASIKLLKGIISIIEKDS
LENTKSRVQSASKFDE
>A0A1B9QQX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio genomosp. F10|TrEMBL
MGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLIAAPHLTCIDASRDELIQIADDYWNNGIQSIVALRGD
IPPGGGAPDMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQG
>A0A363SL69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclales bacterium|TrEMBL
MQRTISFEFFPPQTPEGMDKLRAAWRQLAQLKPAFFSCTFGAGGSTRDRTLETVLDIQSE
GLPAAPHLSCIGSTRDNVRAVLARYKAAGISRIVALRGDLPSGMADPGEFRYANELVEFI
RAETGDWFHIEVAAYPEYHPQAKNPREDLLNFKRKVDAGADSAITQYFFNADAYAHYVET
VRALGVAVPIVPGIMPIANFSKIARFSDACGAEIPRWMRKKFESFGDDSASVRAFGLDVV
TELCERLLASGAPGLHFYTLNQAGLTSTICQRLGL
>A0A1C6LWW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. AmelKG-D3|TrEMBL
MLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSVTYGAGGSTRAGTVRATQQ
IAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHPQGV
TYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFFRPE
DYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATVPEPLKERILAVKDDPAAV
RSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A257AM71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|ANME-1 cluster archaeon ex4572_4|TrEMBL
MKRRSDEIYSDLMRELEEGRYVFTGELEPEKAGDVNEPIEMARELLDLVVACNVTDNPQS
FAYVSSLAASYQIQKETGMECVYQLRCADRNRMALLSDVLGAGVLGIKNILALAGDHVSL
GDTPDAKPVFDLDSTTLIKLIRTVVSEGKDLAGNEIHNPPKLHVGGAAAPGAAHLKAEVA
KVKRKIKAGVEYLQTQVVYFTDVLDKFFKELGPVDVPILVGIFPARTFGQADFFDKFVAG
VDVPPDYLENMRATKQIKDKEKRKEEVDRVNVEFFTGFLEHLKGTPAAGCHMMAVGYPRV
IPALKKIME
>A0A8F7LH58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas aquatica|TrEMBL
MTVAHTKTSNFPISFEFFPTKTPEGAAKHVQVRKDLYARQPEFCSVTYGAGGSTQAGTFS
MVRDIQAEGMQAACHFSCIGATSAKVRAELQELKDMGVKRLVALRGDLPSGYGLGGEFHH
ASDLVEFIRNEFGDWFHIEVAAYPETHPQAKSPEADLKAFATKIQAGAHSGITQYFYNAD
AYFRFVEGIQALGVQVPVVPGIMPILNSSQLMRFSDATGAEIPRWIRLRLQAYGDDVTSI
RAFGMDVVTRLCEQLRDQGAPGLHFYTMNQSAATLELCDRLGL
>A0A7H1JRJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Empedobacter stercoris|TrEMBL
MKVTEHIERANGKPLFSVEILPPLKGQDVNATFKTLDPLVELNPAFIDVTYHRQEYIYKQ
KEKGLLKRYQVRKRPGTVAICAAIQNHYKVDAIPHLICGGFTKEDTEDALIDLNFLGIDN
VLVLRGDPIKSEKSFVPEVGGHAYASELIEQITALNTGNYLDDDLQESHPMDFCLGVAGY
PEKHFESPNLAIDLHYLKKKVELGADYIVTQMFFDNQKYFDFVKKCREMDINIPIIPGIK
PLTTFNQLTKIPQNFYIDLPESLSMEVLKAKDKEAIKEIGLEWCVQQCKELMEFGVPGLH
FYTMSNSINTKKVAEAIF
>A0A0Q4BDA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccales archaeon RumEn M2|TrEMBL
MEGTSILKEKLSRGEFIVTAEIAPPKSASADDFIARAEKMRGFADAYNVTDNQTAMVRLS
SLAGSVMCLRMGMEPIMQIVCRDRNRIAMQSDILGAHALGVRNVLCISGDHQSFGNQPDA
KNVFDVDSTQQIMIFRKMTDEGRLWGGDEIMNPPKLCIGAATNPFGTPMGMHMLRTMNKL
AAGAEFFQTQAVFDLDRFDEWMEGIRKQGIHKKAGIIVGILPLRTVRAARFMMNNVPGTC
VPDTVLKRLTSAADSSAEGLRIAAETIEHVSSQEGVAGIHIMPINWHASVGQLVNMTGLG
PSP
>A0A4Q7Z0M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edaphobacter modestus|TrEMBL
MDRKTEGASEGSAAVKRLFKGVPVLCDGAMGTMLYARGVFINRCYDELNLSQPELVREVH
IEYLQAGAEVIETNTFGANAFRLEHFGIRDKVREINMAGARLAREAVNQIRDKQAAEAFV
AGAIGPLGIRLEPLGKVGLDEAREAFSEQIAALTEGGPGVGVDLLSIETMTSLTEAEQAV
AAARAVAPGVPVIVMVTVDEEGNCLDGTSAEMAARRLSDTGADAIGCNCSAGPATVLSVI
ERMRPLTELPLVAMPNAGIPRAVEGRTIYLTSPEYMASFTRKLVKAGASLVGGCCGTTPS
YTRAMRGALRALDAMESGAEVMERRVEAPTTPKISPPPLAQRSKVGAMVAAGEFVSMVEI
VPPKGINCSKEIDGAAQMHKLGVDAINVPDSPRASARMSAQSLCVQIQQHVGIETILHYT
CRDRNVLSIQSDLLGASSIGLKNILCLTGDPPKLGNYPDATAVFDVDAIGLVNIVRNLNC
GLDIGKNSIGESTGFTISVAANPGVPDIDQEVRRFAYKVEAGAEFAITQPVFDLRVLEEF
LRRIESFRIPIIAGIWPLTSLRNAEFMKNDLRLAVPDGVMTRMAQAGSPEAARAEGVRIA
QEMLAEARPMVQGVQVSAPFGKDKYVAAAQVLGLTEGVGV
>A0A7U3Y882|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain AB0057)|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLDKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A7V4QEK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MTLKEKIEVKKFIVTSEIGPPKGIEVEKILKDIESWRNRVDAVNVTDLQSSVMRLGSLAM
CVLLKERGFEPIFQLTCRDRNRLALQSDLLSAACLGIENVLILTGDHPKLGDHPEAKPVF
DLDSVQLLEVAKRLTEGFDMQGNKLEGKTPKFFLGAVVNPGQDPLEPEIIKMEKKIKAGA
KFFQTQAVYDLKVFEKFLENIKHLKVPILAGIVLLKSAGMARYMNENVAGVFVPDNLIKE
MEEAKDKVEKSVEIASRLIKELKNMCQGIHIMSIGWHKVVSKVLEVSGL
>A0A0C2RJG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. W15Feb9B|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A2E6QZT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium|TrEMBL
MTTLSFEFFPTKSDEGTEKLLTVRDKLAAYNPEFFSVTYGAGGSTRDRTYSIVDEIQQRG
IAAAPHLSCVGDSKAEIRELLNRYKEIGISRIVALRGDLPSGAGLASSELRHANDLVEFI
REETGDHFTIEVAAYPEMHPQAPNLEKDLENFVRKAKSGANSAITQYFFNADCYFYFVDR
VQSMGVDIPIIPGIMPITNYSKLARFSDGCGADIPRWIRKQLEAYGDDSNSIMKFGEEVI
TDMCRRLLDGGAPGLHFYTLNQATPSLVVWKNLIS
>A0A416MG16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium AF25-13AC|TrEMBL
MKVNEILSNGKITLSFEVFPPKTDAQFESVRQATIDVAALKPSYMSVTYGAGGNTRKNTV
AIAKGIQDTTGVTTIAHLTCVGATKENIHNTLDEMKAAGIENVLALRGDRPRDFEGDPFV
DFHYASELVSEIKAYGDFCVGGACYPEGHVEAANKSEDIINLKKKVDAGCEFLTTQMFFD
NNIFFNFLYRVREQGISVPVIPGIMPITRAKQVETARDLSGCSMPQRFLNLVDRFGSNPK
AMEQAGIAYATDQIIDLIANGINHIHVYSMNKPQIAEAIQKNLSEILK
>A0A421K9R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|spirochete symbiont of Stewartia floridana|TrEMBL
MNIKDILKTGKTAMSFEFFPPKTVKGWNKLFSTIADLHRLNPAYVSVTYGAGGSTRDRTH
DLLRRLQMETGMEVVAHLTCAGHTREDIEVILDNYAKSGISNILALRGDIPSDTDSPPGD
FFYAAELTHFIRDTHPEMGIGVAGFPEGHPSSTDRLDEIDKLRAKVDAGADYIVTQLFFD
NRDFVDFVERCRIAGIQVPIIAGIMPIISKSNMTKMARLAPRTRFPAGLL
>A0A1H7USA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. YR750|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPQFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVGFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
VRKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASIKAFGLDVV
TDLCERLQEGGAPALHFYTMNQSAATLAVLERLD
>X5QNA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSJC269B00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A496RLI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MSFKEKVQSGKFVVTSEIGPPKGIETKVLLEDAELIRNKVDAINVTDLQSSVMRLGSLAV
CSLLKERGFEPIFQVTCRDRNRLALQSDILSAASLGIENLLLLTGDHTTLGDHPDAKPVF
DLDSVQLLDVVRTLQQGTDMKGNKLEGQAPKFFMGAVVNPGADPLEPQIMKMEKKIAAGA
QFFQTQAIYDIKIFENFLDKVKRLNVPILGGIVLLKSAGMAKYMNKNVAGVTVPDNLIKE
MESTKDKVATSIEIAARLIKELKPMCQGIHIMPIGWDKIVPKVLDASGL
>A0A1Y0H9M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium Uphvl-Ar2|TrEMBL
MRIRRMLETSEPCFSYEFFPPKTEAGLRKLYGRIEHLSELNPSFVSVTYGAGGGSRQRTV
AMAQHIKKEIGIEVLAHLTCVGHTRAELEELLDELVDVGVENILALRGDRHDEVSEGELL
YARELVALARKRHPHLCIGAACYPETHLESPSPEHDLRWTKEKVDAGVDFLITQLFFQNS
SYSKFAMQANALGIDVPIVPGLMPITNVKQIERFARMCGAQTPAVLFDRLRKWEHDEQAV
MALGMEWAIQQGRELLSFGVPGLHFYTLNSSLATRVVHTSLGGRGRWSA
>A0A660WQ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MSKLRKKLENGEFVITGEVAPPKGTDVSSIIEELKFYKGWVTAVNITDNQSSVMRASPLA
IAKILIDNGVEPVYQITARDRNRLALQSELLGASILGVENVLCLTGDAISQGDHPQAKPV
FDLDSVQMLYTASLLNQGKDLAGKKLNRPTNFFLGAACSPNADPLEPEIIKTRKKIQAGA
KFFQTQAVYEPEKLRQFISDLNEDVFILAGIVFLKSAKMAKFMNENISGVEIPEEIISEL
ESASDPVQKGIEITARLVVELKKFVNGIHLMPLGKAEVVPEILTTAGFSPLQEEVS
>A0A1Z7M635|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drancourtella sp. An12|TrEMBL
MKIREKLQSGKVHISFEVFPPKTDDKYESVLKAVDEIATVRPSFISVTYGAGGGTSKNTV
GIASHIQNDLKVPSLAHLTCVSSTKAEVREVIKKLKEEGIENVLALRGDIPEGMEYPAED
KFQHAIGLIELLKESGDFCLGGACYPEGHVESETQKEDIRHLKEKVDCGLDFLTTQMFFD
NHILYNFLYKIREAGITVPVLPGIMPVTNKSQIKRICSLSGTYLPERFKALVDRFGDNPK
AMRQAGVAYATDQVIDLIANGINNIHIYSMNKPEVAKAIMENLSEIVDE
>A0A354D0M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
PARSPAGTVPARSPVLAGLLLVKSAKMARYMNEHVWGIHVPDDLINRFERSGDARRECVT
VTAELIRAVRGVADGMHLYA
>A0A4P6KCF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter triazinivorans|TrEMBL
MNAVLLTGSAPTRARFSFEVFPARSGAAALALGHAVQHLSAADPDFISVTYGANGSNRDA
SLDLLTYLRDHTDALPLAHLTTVGESREVVRETIHGIMNAGVHDFLALRGDPPRGLGEED
PRVAGSLSALELVELVTEARAERPPLTSVGRTAVAAYPNGHPLSRSRADDIEWLIAKQEA
GAQFAITQLFFRAEEYLSFVSDAQSAGLRIPILPGLMPVSTSGQLRKVASLAGRPAPAGL
EREIEELGGYAPELGVEHTVELARELLAGGAPSIHLYTFNRHEQVLAVLRELHLLTPDPV
R
>A0A356J0V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
LALRGDPPRENPGWEPGKDNFRYSSELCAFIREHFGEYFTIGVAGFPEGHVLCPDRDQDA
RYLKKKTDAGADFVITQLFFNNRDYFDYVGRLRKLGVTNRVIPGILPITNYPSLVKFCAL
CGATVTEEIHKIFNPIQNDHEKTLKAGIDFAVRQCRQLLDGGAPGLHFYCLNKTSPTDQI
LKAVRR
>A0A368TY04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas rituensis|TrEMBL
MSSQEHPLGISFEFFPPGTDAGRDKLMQVCDVLASRNPRFFSVTYGAGGSTQARTREVVR
NVGRSGITTAPHLSCIGSDKGELRELLAQYREEGINSLVALRGDMPSGMGSIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFNKDVENFARKMKAGANLAITQYFFTADAYF
HFVDKARALGVEQPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIGDF
GTEVISRLCQRLLEGGAPGLHFYTLNQSKAPLRVIDNLR
>A0A2W6WUT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp|TrEMBL
MTQTDRARHDAEGPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFVSVTY
GAGGSTRERTHNTVARIAQETPLAAAAHLTCVAASKAEIDDVADAYWEAGVRHIVALRGD
PPEAGTAFQPHPDGYKGAAELVEGLRKRHDFEISVAAYPETHPDALSAQSDIDNLKRKID
AGATRAITQFFFEADTFFRFRDTVAAAGIDADVIPGIMPVSNFAAVQRMSAMCNTDVPAW
MGRLFDGLDQHPAARQLVSATLAAELCRNLYMGGVRDFHFYTLNRAELSYAICHLLGLRP
QVAAELEKTA
>A0A496RYG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MSEFKKALENGKFAVTTEIGPPKGVSLDAVFEELACVRGRVDAVNVTDQQSSIMRLGPIV
MSKFLKDRGYEPVCQITCRDRNRIALQSDILSAYVLGIRNILVMTGDHPLLGDHPQAKAV
YDLDSVGLLHALKELQDGRDLAGNRIDTAVSFYVGAVVNPGADPLEPEIIKMEKKVAEGA
RFFQTQAVFDPRVFERFTAGIKHLRPAPKLLGGIVPLRSARMARYMNANIPGVAVPGPIV
ERLEKAADVEKESVAISADIMSSIRGMCDGVHFMPIRANHLVAKILDRVHGPEGKNNGRE
>A0A229FV18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter cosmopolitanus|TrEMBL
MELSLEFFPPKTEEGAAKLRSVREQLSRALKPTFISVTFGAGGSTQDGTLSTVKEIHEAG
QEAAPHLSCVGSSKEKIRELLQQYKQIGIRRIVALRGDLPSGMGQYGEFHHAEELVRFIR
SETDSHFHIEVAAYPEMHPQAKSMSDDILMFANKMKAGADSAITQYFFNSDAYFRFVDEA
YKLGVDQPIVPGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSFGDDSASIKSFGLDVVT
DLCDQLRVAGVPGLHFYSLNQAETTLTIAKNLDLLKA
>A0A822VGM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDTGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A2D4VGG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvibaculum sp|TrEMBL
MGFDSRKTGDERTQVSFEFFPPKDDKAEEALWKSIKRLEPLNPQFVSVTYGAGGSTRERT
HGTVKRIRNETSLEPAAHLTCVGASKAETDAVIRAYWDAGIRHIVALRGDMPELGAPYEP
HPEGYQSTPDLIEGIKKIADFEVSVSAYPEKHPESESLEADIELLKRKIEAGADRAITQF
VFDTDRHAEFLEKARAAGIDAPIVPGIMPTTNFKGIKRMAGRCGASVPDWLEDYYTGLDE
DLPTRKLISAYVATEQVNTLRGYGFDRFHFYTLNQADLTFAICHVLGMRPKHAAVAEPA
>C5QPD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus caprae M23864:W1|TrEMBL
MSQFLKHLQNNVLVADGAIGTILYSEGLDTCPEAYNLTHPDKVEHIHRSYIEAGADVIQT
NTYGANFEKLKNFGLEHRVREIHKAAVQIAKRAANEDTFILGTVGGFRGVRQEEISLSTI
QYHTELQIDTLINEGVDALLFETYYDLDELKNIVVATRRKYNIPIIAQLTASNTNYLVDG
TEINEALKQLVECGADVVGLNCHHGPHHMQRSFSHIELPEQAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIRYIKSAVQGLTPVKDKKVIPITKKS
NRKPTSVMKQNLTTKVKNGPTVIVELDTPKHLDTDTFFDNVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQRYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A1F5YTG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Glassbacteria bacterium RIFCSPLOWO2_12_FULL_58_11|TrEMBL
MENRFREKLTRSTDFVISVELVPTRGLMRKDFEELISFTEAAVEYGKIDALSLTDNPGGN
PRLAPDVLGLDILYRGMSPLVHLTCKDLNRNGLESRAFQLNRMGVENVLALTGDYPVDGY
QGVARPSFDVDSVGLLNMLREMNRGLKVPLPKPGKFQELEPTNFFIGASVSPFKKQRSEL
LGQYLKLEKKAANGAAFIITQLGYDMRKFDELLRYMSATNLQLPVLGNVYVLNRFVSKIM
NQNQVPGCVVTDELLEFINRHAASDDKGKSAFLEFAAKQVAVLRGLGFRGAHIGGYALSF
EDKRRIIDTAETIASDWRSFIKDLLYPQKDEFYYFRGDPATGLSADQPGKSGENKRPGPR
VTFELMKFIHEQFFEPGTNWFRIARGVCRCIDKSPEATKVFQKFETGVKWLTNNCQGCGD
CSLAELTFLCPEDGCPKGMRNGPCGGSFDGICERKDRKCYWTRVVKRMDKEGGLDKLKEA
KPIIPNAALKDTSSWLNYYLGRDHAALGTNDPVEEKKGKK
>A0A7C3ES32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MNRKQKFLELLENKVILFDGGMGTEIYKKGFFINKCYDELNLSNPSIIKKIHEEYIKAGA
DVIETNTFGANRFKLQKFGFEDKIYDINFKGAKIAREIAGEEIFVAGSIGPLGIQIEPLG
PIAREEARAFFQEQIIPLVDGGVDLIIFETFVYPEELLQGVKSVKTLFPDLPVIAQITID
EDGTTLTGAEPARLIREIETFGADVVGVNCTVGPQVMLNWLEKVRKLTEIPISIMPNAGK
PKNIDGRNIYLASPEYFGEYAKHFAQAGANVIGGCCGTAPVHIKAMRTSLNSLLKDFRKS
RINIEKLDDLPNIEVIPVEKKSRLAKRIRDGHFVKFVELLAPHGVSAEKEIEKAREMYYY
GIDVINIPDGPRASARMSALSLAVQIQKEVGIETVLHYVCRDRNVIGIQSGLLGAYALGI
KNILAITGDPPKLGNYPDATGVFDVDSIGLVNILNRLNHGLDIAGNPIGKPTGFFIGVGV
NPGAINLDEELKRLDWKIDAGAEYIVTQPVFELKVFENFIKKIEHYKVPVIAGLWPLTSI
RNAEFMNNEVPGCNVPDEIMIRLRKVQDSKEKSLEEGIKIARETLSDMLDMIQGIQIAAP
FGRIQSVIQVLDGFNL
>A0A7V5FF86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MKKPFRDRLRDGPILCDGAMGTLLDMYGYRELPHEMEVLRHPEIVEKIHREYRDAGAEIL
ETNTFGANSLRLAEYHLEDHVREINLKAVEIARRVAEDSLYVAGAVGPTGKFLEPIGSLK
RGDARAVFREQIEVLVESGVDLIMLETFVSLEELDEAIAAAKEVADIPIVAQRAFPEDGS
VLATNFPAEVLEHIWKRGVDVVGSNCTVGPQRMFTIMRTMHNSGVYLSAQPAAGVPTLVD
GRAVYHATPEYLAIYARELLKTGVTLIGACCGSTPEHIRSIAKVLKEFRETSSSTGEVRI
TEVTDRSRSQASFAKESAAVRLEEEKREPAPGEELKDRSVFASNIGKKFLTSVELDVPRG
IDLSSIFEGATYLKQQGIDAINITDGARARLRMSPIAISHLVQQRIGIEAITHMACRDRN
LLGLQSDLLAAHALGIRNILAVTGDPTSIGDYPQATSVFDIDSIGLIRAINAMNHGQDIM
GNSLGDSTSFLIACAVNPLADNPEREIERLTKKVESGAEIAFTQPIYELQTLEDFLLKIE
HLRIPLMVGILPLRSYRHAEFLHNEVPGISIPEKIRERLRNARDRAPVIGVEIAGEFLHE
IRTMVQGAYLMPPFRKYQIVVDILGMM
>A0A2X4XLG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DNDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A831YFF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrobaculum sp|TrEMBL
MEIIAEVTPVRDRAKLLKKLEALKPLVNRIDIPEAPGGKPTAHSLAVGVLAKQMGFEPIV
HIRLLDVNKTGLKSLLGGAYLLDIKDVVVLQGDPPAEGRPVGEVSTEEAVEEAKKMGLRA
GALLSLRRDHRKRVETLRADFYLALHLTDAKQLEGLPPIVYPYVMVRTSNNSELIDRLRQ
TAVEPHEALALVEALEGAAPGAVISVPGDFDALVGLLKQIKTRRG
>A0A3B0J9L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila guanche|TrEMBL
MCAKILNKTKRNLSIIIKINLLEVRNAWGYSESRNAFICRLDCAPARRLHNHRVPISSRA
SGKLIKTNAKWKPTVRTQFQCREICRWVSNICGSLLRDMHALEAASSGLATTSYVPCVNY
TTGQTSGTDFVERRVATLVAERTARRQLFYGIEVVALQSGKPTCLDFNRFLPILPTFVSI
VWLGTEYCHVNPIDQVKSLQLARSLESRIAVLPHITAYCLSQERLDQFLALNFTNVLPIR
GDLVHEIQNFTYSWEIVEYIRKQQGDKVSICVAGYPEGYTSLPQRQDPAEAMRFLKRKIA
AGADCIITQMCYSSETIIQFIKDCRSAGITVPIVVGLTVADCFRTYCLSEHIAGVHLPPE
KREELLLIHKEPQRVARFFVQLILRIIRDVLDADVGVYGIQFFTFNKFEPVYELLKELRT
LQILKD
>A0A3B8WW95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
QSAGIHVPVLAGIMPITSSSQVSRMIDLSNAYVPRKLLAICDRFRNDNDAMMQAGIAYAT
DQIIDLISNGIRGIHIYTMNKPQIAEAIMKNIDSIVRAVNK
>R0IFT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Setosphaeria turcica (strain 28A)|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDEALEQAQVLGIRNILALRGDAPRSEE
YRDEDTPPEQDSNKDFTWAVDLVRYIRKSYGDYFCIGVAAYPEGHSDQSHPEHQDPLFDL
PYLVEKTKAGADFIMTQLFYDVEAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHAKLPAEILARLDAVKTDDELVKQVGVQIMDEIVEHIKARPDTCRRGFHFYTLNL
EKAVSHILEDTNLIPSTIIEDGEVIVETTPAINLEPPPNGFVPHRRRSSAVNSGPRNRVI
VSHISAARSSNPSYEATEEEAGAPRGPINTRATTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKSDISALFRRHIEGDLEAIPWSEQSLSP
ETMTISKQLLALNAKGWWTVASQPAVNGVKSTDPIFGWGPKNGYVFQKPFVEFFIPASEF
AALQPKLDAHEQVTYFAGNAAGDFEASQEDSVNPVTWGTFAGKEIVTPTIIEAVSFKSWL
EEAFSIWQEWQRIYPPRSASSTLLGSLRRDYWLINVIWGDFVNGEGLWEFLGQ
>A0A3P7PCJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrocella atlantisensis|TrEMBL
MLRDKIINRESGMIFYGLTPPKSNNTDEKIEAISKKHIARIKELDVDGVIVYDIQDETER
THEERPFEFIHTVDPSLYSRHYLKELNVPRVVYRCVGNYIEEAFVEWLKDGEDQFTVFVG
TASTHQEVGLKLDEAYKLRQKYNDDMLLGAVTIPERHRLLGDEDERVGFKMSKGCRFFVS
QAVYDLEASKKFLLDYKQYCLKHEMDMVPIIFTLTPCGSAKTLKFIKWLGISVPSWLENT
LLTSEEMLSKSIQLITVIYKELTKVAKAEGIPIGCNIESVSIRKEEIEASILLAKEITAF
VKLQK
>A0A2X0LP10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbotryum saponariae|TrEMBL
MRICFFLQIFLCDPLLHPLHLPCLAQLPAYPPTRHIARPPPLFPFVRTVRPVQARSFARF
RIQPTVFAPQVAPRRLFPSYKIASLGPDEPFYTFEVFPPKTSPGVSNLISRLSRMSSLNP
SWIHITWGAGGSTHSTSLQLAEAIVSKTNGLGLDACLHLTCTNMERSVLDEALKRAKELG
VVNLLALRGDPPRGEEYWVASDGEFQHATDLIAYIKEHHGNDFCIGVAGYPEGHADSADK
SADIDYLFAKQQAGAEFVVTQLFYCVETFLKWHKACRDRGITIPILPGIMPIQNYQSFRR
MTNLCKSHIPPQIVKDLELIQHDDQSVKDYGVRLAVSMMRELWQAGIRGYHLCTLNLEKS
VSRVLEQLDWVEHPPPSPLIKEPQANGVDTSKPSSLLPSQVELLRAKGSKGGVDGQGARK
DSPTSWDEFPNGRFGDARSPAYGDLDGYGVGLKLTPAEALRQWGSPTTLADVSNIFSSYL
SGKQASIPWSEEALRAETKTIAQHLIRLNDERHWWTVGSQPAVDGAPSGDPVYGFGAKGG
YVYQKAFVEFFLTEAELDQLERRAEEDAKARQEKDAGEGLIKWYAGNREGRLRSNMKKDN
VNAVTWGVFNAQDIVTTTLIEEMSFKAWSEEAFAIWLEWSHLYPANSASRRFIRELADTR
WLVSVAHHDYKQIDGLWQWLLAAPKV
>A0A1M3MME4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 63-22|TrEMBL
MGFYGLSRRPDVGQTTKVSFEFFPPNSEKMEERLFETVTRLAPLKPEFVSVTYGAGGSTR
ERTIRTVARILKETDIKPAAHLTCVDATRQEVDGVAREFAALGVNRFVALRGDPANSGGG
KYAPTPGGYQNGAELVGGLRAIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGLLPVHNFKQVKNFCVRSATHIPAWLAERFD
GLEDDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKAEAEA
A
>A0A520J8B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
MSISIPQLAEARRALEEPLFADLAGDVGLSFEFFPPKSEKMEAQLWEAIRTLEPLGPDFV
SVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIVA
LRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNLK
RKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITA
>A0A0P9NXJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. castaneae|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A0F2PIC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium BRH_c8a|TrEMBL
MKVIDIYSNATKPVFSIELSPPLNGTSLDPIFNTVSGLMKYEPAFVSVTCSALGSARGGT
IPIAGKIKRDYGIESVVHLTCVAKSQQDIDNMLMDVRYEGVQNILALRGDPPKGEKEFRP
HEKGHRYASDFVSQIKRLNQGKYISFNEGEYRNGEPNNFCVSVAGYPEGHPECPDKEKDL
EHLRVKVENGADYIITQLFFDPEIYFRFVDRVNNMGIRVPVVPGVMPVESFAHLDFILKQ
PIGVSVPEVFVDKLRKYKEDGDNASALQFGVEFISSMCNALIEGGAPGIHMYTMNTPDRA
AKIFDAISR
>A0A672L490|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus grahami|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDTDRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAETFLRF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGI
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFALLDSPRETQEEGSQL
>A0A7S3RLW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strombidinopsis acuminata|TrEMBL
MKLRQGESLPVLRRGAALEPGWFSFEYFPPRTDEGVENLRKRIVRMKNLNPMFTDFTWGA
GGSTSELTLTLTSAAKNEYGCVANMHLTCTNQKAEMVGDALTKCKELGVRNIVALRGDPP
RGSEKWEATEGGFNCALDLVKYMRKEHGDYFAISV
>A0A1Q8JGF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. Ae356_Ps1|TrEMBL
MVTSVTTTSASTVTERISVDRPFFAVEFFPPKDDQGEADLWRAIRRLEVLDPAYVSVTYG
AGGSSRDRTVRTVERIASDTTLCSMAHLTAVSHSTEELRHVIGSLAAAGVRNIMALRGDP
PGDPLGEWVKHPEGLEYADELVSLIKRSGPFCVGVAAFPYGHPRSADVESDTEKLVGKFR
AGAEFAVTQLFLEPDGFLRLRDRVAAAGFDQPIIPGIMPLTSEKTFHKGPELSGSPLPEA
LVERLSKYSGDAKAFREAGMEVTGELCERLIAEGVSGIHFYSLNRSTATTELVERLGLAA
QPAGADRAESEAVLPV
>R6F1C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:145|TrEMBL
MKLINLLKRDDLSLSFEVFPPKADSSFDSVKAATEEIAKLKPAFMSVTYGAGGGTSEYTL
EIAKNIKDMYGVSTLAHLTCVSSTHEAVRQKIDQIKEAGIENVMALRGDIPEGMDLSHQE
TWHYHHAIDLIRELRESDTDFCIGGACYPEIHPESTNQKEDIKYLKEKVEAGCEFFTTQM
FFDNNLLYNFLYKIREAGITVPVVAGIMPITNAKQVERAVKLSGSHMPQRFKSLVDKFGS
DPAAMKQAGIAYATDQIIDLFANNVTNVHVYSMNKPDVARKIQANLSDILGKE
>U1SFZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alloscardovia omnicolens F0580|TrEMBL
MHKPQFSLEVFPPRRNGPVGSIYDTLDGLQGINPDFISVTYGTGKTADRTATARICHTVR
QEYNIPVVAHLTAQYLDKQQADEALDMFKQAGVSAVLALRGDAVEGREPTGVFKYASDLV
RYIREQCPDLKIFGACYPEVHPNSAGVVDELRHLKTKVDAGTSNLITQLFFDNDDFFRFV
EQARIAGIDVPIEAGIMPVTNAAQVRRMVTMCGARIPKELSAMLERWGDDPDAIRQAGVL
YASQQIADLVSRGVDGVHLYTMNHPCTTRRIWANVSALFKEV
>A0A318MI80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium asteroides|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLMPDFISVTYGTGRRSDRTATARIAKTIH
TEYGIPAVAHLTAQYADREVIDQALDMFDDAGVAAVLALRGDSVEGREPAGVFEHASDLA
AYIRSRRPNLSIYGACYPETHPEAASPEEDIENLRIKVDSGVDHLVSQLFYDNADFLDFL
DRARAAGIQVPIEAGIMPITNEGQVRHMSEVCKARIPAAVESILERWGDDRASLREAGII
YASQQIADLVAHGVDGIHLYSMNHSGVTRRIWHNVRHLFRQVGTKEEPVNSQN
>A0A2E7CVZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVIDYIENSKETIFSFEIIPPLKGKGIEDICEGIDPLMDFNPPFINVTYHREEYEYKKM
GNGLLKKVSVKKRPGTVGICAALMNRYKVDAIPHIICGGFTKEETESALIDLKFLGVDNI
LALRGDPMKNEAAFVPTKGGSQYAVDLIDQIKDMNNGQYLYEETKNSPSNFCIGAAGYPE
KHFEAMNLNSDMKNLKKKVDAGAEFIVTQLFYDNKKYFDFVKKCREIGINVPIIPGLKPL
TTLRHLSFIPKFFHVNFPEELSNELEKCKTNEEVQKVGVEWSIKQARELIKKEAPVLHFY
TMGKGEAVRKIAAQVF
>A0A0Q4TEV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Leaf83|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRVFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLPR
>A0A2H6IX78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Bbin10|TrEMBL
MNNSGLDFKNFEETRPGHTSRGRLERILRRGEFAVTAELNPPDSADPNEVFKRGAIFDGW
VDGINATDGSGANCHMSSVGICALLTRRGYAPIMQISCRDRNRIAIQGDVLGAAAMGVSN
ILCLTGDGVESGDQPGAKPVFDLDCMSLLETIRVMRDEGRFLSGREITYRPHLFLGAAIN
PFAPPYDFRPLRLAKKIEAGAQFVQSQYCFDIPMLKEYMNRVTDMGLHEKCFILIGVGPL
ASARAARWIRTNVPGIHIPDAVIARIEGARDQRQESKKICIEIMQQIKEMPGVSGVHVMA
YRQEELVSEVVHESGVLQGRKVAVGTELG
>V4QKU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asticcacaulis sp. YBE204|TrEMBL
MSPPPAFVQSAIARSVRAGAAHLNVSFEFFPPKSEEMEQTLWSAIRRLEPLNPSFVSVTY
GAGGSTRERTHRTVKRILDETGLRPAAHLTCVEASREEVDEVIQAYWDAGVRHIVALRGD
PPTGLHDGQYVPRADGYQNATELTAAIKRIGDFEVSVGVYPEKHPQSPSLDFDLDVLRQK
VDAGATRGISQFFFEPETFLRFRDAVAAADIRIDLMPGIMPVTNFKGLRRMAAACEAAVP
DWLAELFAGLDDDAETRKLLASAVAVEQVLGLEREGVANFHFYTLNRAELVYSICRVLGL
KETTGKSRTAI
>A0A239CQ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter ummariensis|TrEMBL
MKVTEHFKKADGKTHFTFEILPPLKGENLRTLFDHIDPLMEFNPPFIDVTYHREEYVYKQ
RENGLLEKRTTRKRPGTVGICAALQSHYKVDTVPHLICGGFNKEETENALIDLHFLGIDN
VLVLRGDCVKSESRFTPEPGGHRYATELMEQVIDMNNGRYLDDEQVNTYGTDFCIGVAGY
PEKHSEAPNMQADLRWLKKKVEMGADYVVTQMFFDNQKYFDFVQLCRSEGINVPIIPGLK
PITTKTQLTILPSIFHIDIPCDLADAVEACADNKAAAQVGVEWAIKQSKELMEFGVPCLH
YYSMGKSGSVRKVAEALF
>A0A0K2YIJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. RD6.2|TrEMBL
MTRTPSIVDRIGAAEGRIPFSVEFSPPRDADAEARLWRAVREFERMGPAFVSMTYGAGGS
TRDRTVRVTGDLAEETTLLPVAHLTAVGHSVDELRTMCGAYADRGISNVLVLRGDPPGDP
LGDWVKHPEGVEYAEELVRLVRDMGDFHVGVASFPEGHYRAPDLDHDTKYLVAKLRAGAE
YSITQMFFDVDDYLRLRDRVAALDPEQGAKPIIPEIMPITSLRSARRSLELSGSKLPAVL
EERLTRAAGDGPEENRAAVREVGIEVATELAERLISEGAPCLHFITLNFARATREVLTNL
GLASHVA
>A0A423HY52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas frederiksbergensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLSQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A7X5DEP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MEPVASLFAPRSIPFSVEMFPPKGSLTLDAARKVVGGMALARPDFISVTCSAGGSGNGGQ
TIEVASLIQSEAHIPAVAHLTCVNSTRETVQAAIAELKAAGITTVLALRGDLVGNAQPGD
FRHGADLIPLLKDAGFCVGAAAYPEGHLDCLDLDEDLRHLREKQDAGADFFVTQLFFDNA
DFYRFRERALAAGVTRPVTCGVMPFLGKSQIQRMVFLCGSSLPSPIVKLLAKHEDDPAAL
RAAGVEYACRQLVDLARNQVDGVHVYSMNHPDIAQAAATALADAGFRA
>A0A0S4MSH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thermokryptus mobilis|TrEMBL
MKKPFVERLLDDRPIICDGAMGTMLDLYEYPEQPRCIHNILNPDIVERIHREYIEAGAEI
IETNTFDANRFRLEFYHLQDKIKEINKAGVEIAKSVAGENVYVAGSIGPTGKLLEPLGKV
KIQQVKDAIKEQAEILIEAGVDLIILETFVSLNELDAAIDAVKEVSDKIPIIAQKTFPED
GAILATDFPIEVVKHIKEKGVTVVGSNCTVGPQRMFSIIKNMYQDDVILSAQPAAGIPTL
VDGRSVYHASPEYLATYAKQLVEAGVKIIGACCGSTPSHIKAIAQAIKDIKLKKPKIEIK
AKQIQDEKKESTIIIEDKRSDFAKKIGKKFLTTVELDIPRGVDMSSVIEGASYLKENGID
AVNITDGARARFRMDPVTISHLVQTKTGMETITHIACRDRNLIGLQGLLLGAWALGVKNI
LAITGDPAKIGDFPNATTVQDVDSIGLIRILKNMNHGLDAMGNTIGEPTHFLIACAVNPT
AQNLDYEISRLEKKVEAGAQIAFTQPLYEMKTLELFIKKIQHLKIPVMLGILPLRSYKHA
EFLHNEVPGIFIPDWVREKLFLARDDAGKVGVEISAQFLKEAKHLVQGAYLLPPFKKYHL
AVEILQKI
>A0A6I0BVP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. CH126_4D|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTKIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANITPVIEKDTVQRPKVVH
KHEKRSKAHVTLAAKAKKQTTVVVELDPPKTLNTQRFFEGARALKRVGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIEAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A117SLZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp. BRH_c37|TrEMBL
MENKFKESLLDKNTLSVTWELVPGRGANEKAQETAITSAAQAAKGGRVHALTITDNPGGN
PAILADYLGMEILKMGIEPLVHFTCKDKNRNQMESQLYALDRAKVRNLLVMTGDYTYSGF
KGRPKPVFDLDPSNTLQLITEMNKGLEVPGMKGPTYHAPSDFFAGAAVSPFKSTEAELMV
QYYKLKKKIQGGAQFVVTQLGYDARKCHEVIQFLKVNKLDIPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNTEKSAQDKGVGQRMLRAAKLYAILKGIGCAGVHIGGHNLKYEQ
LEYILDKGEELSPNWQDLVKEFDYPQTNGFYYFEKDEKTGLNTDRPTNRANLPLDAPAGA
MYTMMRGMHGLLFTPNKKLFPMMRSIYRSAEGKKKTEKRLHAVEHLAKVVMLDCKDCGDC
AMLDLAYLCPMSQCPKNQRNGACGGSLDGWCELYPKEKKCVWVRAYARLKKYGEEASLDV
PPVPPANWDFYQTSSWSNFYLGKDHSAPILGIKRPESKLPEIKK
>A0A7V6JJH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MRISELYKKKGQTLALEIFPPKPDMPMDTLFSSIEGFKKLSPDYISVTYGAGGSQRGRTV
EIASKLKNHYGIESMCHLTCVGHSVEEIDDLLARIKEENIDNILALRGDPPLDQPDFSYE
SGAFKYANELIAHIKKTDDFCIAAAAYLEGHSDSKRLSDDRRYLKQKVDAGVDLLITQLF
FDIRLYFDFLDRCEQLNINCPVIPGIMPIFSGRIKTMTARSGCSIPANLVLMIDKYQDSP
EDLKKAGEEYAAYMIRELLDGGAPGIHLYTMNKLESTVNILKLAGLR
>A0A2N2HM38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-19|TrEMBL
MEIKKILKENRFCLSFEVFPPKREGNLENLFATIGELSTFDPDFISVTYGAGGSTRDKTL
EIASKVKNDFNREVLGHLTCVEATRDDIARTLDAFQERNIENILALRGDPPTGQEKFTPT
PGGFAFANDLVEFIHRKWPFCIGVAGYPEGHPEAASLDDDLKNLKKKVDAGADFIVTQLF
FNNEFFFRFRDRVRAMKIQVPILPGLWPILNYNQIKRIVGLCGATIPSGLGEKLDRVMDR
AEEVEKYGLDHAVRQAEELIRNGVDGLHIYCMNRSEPVRAILGAVSIPKGKADTPGTAKP
GRIQS
>A0A2M7NNE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium CG_4_10_14_3_um_filter_31_253|TrEMBL
MKITDHIKNSNGKTLFSFEIIPPKKGNSIQELYNNIDPLMEFNPPFIDVTTSREEYIYIS
KENGLLERKITRMRPGTVGICAAIKHKYNVDPVPHVLCGGFTREETEYLLVDCHYLGIDN
VMALRGDAMSHQKYFEPIEGGHEYARDLVAQIRDLNAGKYLNDVQESTDKTDFCVGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGSDYIVTQMFFDNSKYFEFVDAAKNMGIHIPIIPGIK
PLAVKRHLQLLPQVFRIDLPESLITEVEKCTTNSQVKEVGIEWAIQQSKELLAAGVPVLH
YYSMGKSDNIREIAAKVF
>A0A3S2L312|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.001.01.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A1C0UU30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. MBR 210|TrEMBL
MEDNHSCAALNYFRKAAQAGEFLVTAEVAPPKGGNSTHMIEMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQNGIEPICQMACRDRNRIALQADLMGAHALGIRNILALTGDPVKA
GDHPDAKGVFDLESVRLLQLIQKMNQGVDCNDKPLTDGATDLFVGAAVDPQCGSWSGLQS
RFERKVAAGAQFFQSQLITDFERLEKFMDKIASVHNKPILAGIFLLKSAKNAQFINRCVP
GVNIPEHIIDRLAKAQDPLEEGVKIAAEQVQTARQLCHGVHIMAVKREDLIPKILDLAGV
KPIDLVVAK
>A0A423FR07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas brassicacearum|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
QDVITQMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1Q7D675|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_2_20CM_2_66_6|TrEMBL
MVRPLGAQSVGQALAGLLRTPRYEIFPTDGVVELVAAHVPKEVTLTVTASPRRGLPATVV
LAARLSRLGYRAVPHLSARLIRDRVELGQILDALKAAGIRNVFVVAGDAREPAGQFPDSM
SLLAALPPDHGLTEIGVTGYPESHPFIHDDVTIQAMWDKRRLATYIVSNLSFDPATIKRW
VERVRRRGVQLPIYIGMAGVADPARLLRLSTRIGMAESARFLRGHPSWLARMFRPGGYAP
GRFVSALLPDLAQPDRRVAGLHVFTFNEIEPTERWRQEMLARYAQEVV
>A0A222E4A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Antarctobacter heliothermus|TrEMBL
MQRPEISFEFFPPKNIEATFRLWDAVQVLSPLAPRFVSVTYGAGGTTRDLTRDVVATLHK
HSGLRTAAHLTCVNATRAETLAIADGFAEAGVTDIVSLRGDPPKGSAGFEAHPDGFANSI
ELIEALAETGKFTQRVGAYPDPHPEADSQQASIEWLKRKLDAGATEALTQFFFEADTFFR
FRDDCAKAGIDTSKLVPGILPIENWNGARRFAESCGTYIPAWVSDAFEKAKRDGREDLLA
TAICSELCTDLIEGGVDKLHFYTLNRPELTRDVCFALGVTPEVNFEQVA
>A0A417RYX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM05-6BH|TrEMBL
MKITQLLQEDKVTLSLEVFPPKKDTAVEQVSQSVRAIAALHPDFMSVTYGAGGGTSAYTV
QLAQEIKAEYDVPSMAHLTCVSSTKETVKKQLECMQEAGIENVLALRGDIPADTEFPLPD
QFHYAVELVRYIKQIAPEMCIGGACYPEGHPEAVSKAQDIQHIKEKVDAGCEFLTTQMFF
DNSIFYNYMYRLREAGVLVPVIAGIMPITRKNQVERSIQLSGSCVPARFKSIVDWFGDDP
AKMKQAGIAYATDQIIDLIANGISHIHVYTMNDPEVAAGIMNNLSAILH
>A0A351WW88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
MRIIDKINQGRQFISLEFFPPKDKNEWPAFFAVAERLSRLEPLFASVTYGAGGSSKGETL
EIVSRLKNEYGMETMAHLTCIGSYRGDLQQFLDNLALAGVNNVLALRGDLPVDAPPEFSA
CRTLLHACDLASFIRETHPRMGIGVAGYPETHPEAVDPETDLKYLKLKLNSGGDFAITQL
FFENSHYFEFVKRARAIGIDKPIIPGIIPVVSLKVIRRIVSLCGAALPPAYLAQLEEADR
SGGPAAVQRLGVAYAKRQAQELLAAGVPGVHIYTLNRDEAVLDLVEGLLPS
>A0A7R9C2B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Notodromas monacha|TrEMBL
MPESAAGDIGNEDSPSSVVLMSSVVGQGQGQVLHQQQQQQHALRPSSSFCSSLASDSESG
MDSEVEWDEEPPEGGYNDGDEAAVSVPGAYMTLRDKIHERIKAGDKFFSLEFFPPRTKAG
AVNLLSMLVGWRSIDGDLPPGPKLVKAELVLDMEAPIPDTWIHFWQTQRDSWKKGVIFVN
GFPLGRYWDKGPQQTVFLPGPFLRPGVNEITQFERMGSAGALFIDVTWHPAGNPAGETET
SSMGIANAALNYCGLETMLHMTCLGKTPQ
>A0A6N8S4M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella kummerowiae|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTTELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAAMG
VTNMMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNGKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGV
GPMASAKTAKWIRSNVPGIHIPDSVITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHDSGVLKGRKPWKREPNPVDQLVAERIERTREGVEQNQQQMAEKAA
HHPH
>A0A380FAH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus carnosus|TrEMBL
MIRFLQTLKENVLVADGAIGTILYSEGIDTCPEAYNITHPKKIEQIHRSYIQAGADVIQT
NTYGANFEKLQTFGLEHQVKDITRAAVRIAKKAANEDTFILGTVGGFKGVKQNELSLSTI
LYHTDIQIDTLIDEGVDALLFETYYDLNELLQVIRATKKKYDIPVIAQLTASNTNYLQDG
TEINEALKQVEAEGADVIGLNCHHGPHHMQQSFTHIELPQHALLSCYPNASLLDFENSSI
KYSDNASYFGKIAKSLVKEGVHLIGGCCGTTPEHIHYIKEAVEGLEPINEKKVIPIRRKS
NHPSIPVQKDNLTTKVKSGPTVIVELDTPKHLDTTKFFVNVTKLDKANVDAITLADNSLA
TVRVSNIAAASIIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKV
GHLPGATNVYDVNSKGLTELAVRFNQGLNIDGGALKTTTNFNIAGAFNPNVRKMEAAVRR
LDKKLDSGMNYFITQPVYTVEKIQEIAEKTAHLDSPFFIGIMPITSYRNAQFLHNEVPGI
TLPEDVLEQFEAVKDDKQKN
>A0A849HWQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidocella sp|TrEMBL
MNSLSPMRQGAPAFAHAAGDIEVSFEFFPPKTDKMDAALWETVQNLAPLGPRFVSVTYGA
DGSTRERTHATVTRIAHETPIPAAAHLTCVGASKREVLEIAQSYWAAGIRHIVALRGDPP
QAGQRFTPHPQGFANATALTAALKAVAPFEISVAAYPECHPESLSIQADLDNLKAKIDAG
ADRAITQFFFSPEAFLRLRDRAAAAGINAEIVPGILPAANVAQTRKFAAQCGTAIPPWMN
RLLEGLDEHPETRQIVAATIAAEMCMKLYESGVRHFHFYTLNRAALCHAICHLLGKTPAA
YTPELAGATGM
>A0A3A6FT72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium AM25-39|TrEMBL
MKLSDAMREKMLLSFELFPPKTDKGMENLPGTIEHLCKYKPEYISCTYGAGGTNVGKNMD
VCKMIKDAGTIPVTHFTCIGNTAEGIKDQLQNYLDNGVDHMLALRGDLPFGWTGTGGDFA
YATDLVAYVRKEFGDKIEIAVAGSPEGHISCRSLEADIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRCAGITMPVDVGIMPILDQAATINMALSRNACVMPRELCEIISKNWIFPN
PFVQDPFDADVEGKKARFKEAGIEYTIRQIDEYRACGIDGIHLYALNKWKDVSEIIDRSG
LRTLV
>K4AMY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Setaria italica|TrEMBL
MKVIEKIQQAAADGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLDIANRMQNMVCVESMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATPEAYNNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVDDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTK
IPAEITDALEPIKENEEAVKEYGVHLGTEMCKKILASGIKTLHLYTLNMEKSAIEILKRL
GLIEEFKVSRPLPWRPPTNVFRVKEDVRPIFWANRPKSYIRRTLGWDQYPHGRWGDSRNP
SYGALTDHQTRGRGKKLQEEWAVPLKSVEDISERFTNFCRGKLTSSPWSELDGLQPETKI
IDDQLVKINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLV
EKIKAFPSLTFIAVNKYGVSASNIPANAVNAVTWGVFPGKEIIQPTVVDSGSFMVWKDEA
FEIWTAGWACLFPEEDSSSKELLKKVQDNYYLVSLVDNDYIHGDLFAAFKEI
>A0A4R9AF04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Sr39|TrEMBL
MSACDARLAFSFEVYPPKTVAAASALTRTIDHLAAAGPEFISVTYGANGSSRNSSLDVLR
YIKDQTSADAMAHLTCVGSSHTEASRLIREFLDAGIRSFLAVRGDAPQGAAPDDTTFLGD
LHSAGELVQLIHRVQAERVPYTETVIPGLPSARGVKTERSKVRIGVAAFPNGHPNSRSVT
QDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLFPILPGIMPVTSPNRLRRI
LQLSGEKLPAELSIELEVEPTEQGQRQIGIDYAVRLSQDVLAGGAPGLHLYAFNQHDTVL
SILEGCGARPVPAAMP
>I4JQZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri TS44|TrEMBL
MSQEPRYSFEFFPTKTEAGHEKLLNVARQLAGYHPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLEIYRKAGIRRIVALRGDLPSGMGLASGELRHANEL
VEFIRSETGEHFHIEIAAYPEMHPQARNFEHDVANFVRKAQAGANSAITQYFFNPDCYFY
FVERVRKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIDSIQAFG
EQVISEMCEKLLAGGAPGLHFYTLNQAGPSLAIWNNLGLPRQA
>U2TDN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mitsuokella sp. oral taxon 131 str. W9106|TrEMBL
MGRDIVSRKEQEAFMKRISVELVPRDEEALRAELAAVGKYRSRIGVINVPDLLRLPLRSW
EGAAIAQESFPSAMPHIRAMDIDLDAGLPMKAYLRAHHIEEVLVIEGDPPQDMTREVYPT
MSVDVIRKFRAEMPEVKVYAGVDQYRGSMAEELYRVRRKAQAGAAGFFTQPFFDLRYLAL
YADMLGGYEVYWGVSPVMSARSESYWERKNKVVFPHAFRPTLDWSIGFSREAMAFAETHG
ASVYLMPIKTNLEAYLSGVFA
>A0A428Z1V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kibdelosporangium aridum|TrEMBL
MTSVLERINVGRATFSVEFMPPRDDADEQILWRSIRELEGLDPAFVSVTYGAGGSRRDRT
IRTTGRVARETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVHNVLALRGDPPGNPMGEWV
KHPQGLSYAEDLVRLVRELGDFCVGVAAFPYGHPRCSDIETDADRLVQKFRAGADFAVGQ
LCYSASDFLRLRDRVAARGSDAPILPGVMPLTTPKMLSKVVELSGAPVPPQIKSRLEPLM
DDPKAFRAEGIDVVTEMCQELLAEGVDVLHFYTFNRAKATKEVLGRLGLVPSRTA
>A0A1I7BF20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora righensis|TrEMBL
MTRVVDRLQPGRTVFSVEFFPPRNDDEERILWKAVRELEPLDPAYVSVTYGAGGSSRDRT
IRTVGRIAQETTMLPMAHLTGVDHSKDELRHVVGSLASEGIQNILAIRGDPPGDPMGEWI
PHPDGILYADELVRLVRSCGDFSVGVAAFPHMHPRSTDIETETDHLVNKIRAGSDFAVAQ
LFLQPEYFLRLRDRLAARDCHAPLLPGVMPITTPKVLSKFQHLAGVPVPAEVSNVLDPLV
DDPKAFRAAGIELSTKLCERLISEGVPGLHFYSLNRAKATREVVDNLGLAEGVLQPA
>A0A4S2RZP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. A1277|TrEMBL
MALGTPSTRTDHARTVREMLATGETSYSFEFWAPKTEKGERNLWNALRRVEAVGPSFVSV
TYGAGGSTRAGTVKATQDIAAESTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGPWVEHPQGVKYAADLVRLIKEAGDFCVGVAAFPERHPRSADWDTDVRYFVD
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCDTPIIPEVMPVTSVRQLERFAQLSNATL
PAELKERILAAKDDPAAVRSIGIDFATRFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A0T7FNY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neorhizobium galegae bv. officinalis|TrEMBL
MTADSQTFSVSFEFFPPKSEEMEGQLWDTVDELALWDPRFVSVTYGAGGSTKAPTINTVR
RLVGETSLATAAHLTCVDATREETHSVVGEYRAAGIRHIVALRGDPASGVGTDYRPHPQG
YANAAELVRGLTELGGFDISVSAYPEKHPESADLGADIEMLKRKADAGAARALTQFFFDN
DVFERYLEKVRAAGIAIPIVPGIMPIQNLTQLKRFAGRCGSSVPSFLDARFQGLDDRPED
RASVAADIAAEQIEDLIRRGLGDFHIYTMNRAPLVSAVLQRLGRRQIRTPRNAAA
>G2LHT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloracidobacterium thermophilum (strain B)|TrEMBL
MKVLKPFRELLAADGIHVFDGAMGTLLYAKGVYVNRCYDEISLSNPALVQEVHREYVKAG
AEIVQTNTFGANRPKLEMHGFQDRVQEINYKAAKLAREAVGPQVYVAGSIGPLGIRIEPW
GPTSFDEAKAFFREQAEALLDGGVDLIVLETFTDLTEIRQALAAVRELSADMVVVAQMTV
GEDGATGYGTAPEIFTKRLDEWGADVIGLNCSVGPKPMLEAIERMAAVTEKPLSAQPNAG
LPQDLQGRKIYLCSPEYMAKYARRLIQSGVRFIGGCCGTTPEHIKTLKAAVRALSPAKRI
EPVIQVLETKCPDVRITPPEEKSRFARKIVQGEFVTSVEIVPPRGCDPTKMLEGVRLLKA
AGVDAVNVPDGPRAQSRMGAIATSLIIEQQVGIETVTHYCCRDRNLLGMTSDLLGAAALG
LRNILLITGDPPKMGPYPDATAVFDIDSIGLTNMVKRLNLGLDLGGNAIGQPTSYFIGVG
VNPCAVDLDYEIRRFEYKVEAGAEFAITQPIFDIGMFRAFLKRIEHCRIPIIAGIWPLTS
YRNAEFLSNEVPGVVVAPEILERMRRANTSPEAGQQEGLAIAREMLSEVRDLVQGVQVSA
PFGRVAYALEVFEVLRETVG
>A0A848ND16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter ruhlandii|TrEMBL
MNSLKQALDEKRFACVLEVIPQQSPARLAALEPIMRRGQLAGWPLLPAFADRVGPHADLS
PLQGAGALGDPASSLLHFSGKDRERADLLRQMAAMGARGLKQLLLLSGDRLPGHDPGRAP
VRYLESVPALQIAREHGPDWLLGAALNPFKYREEEGGAQYLKARKKLLAGADFLTLQLGF
DAAKHIEAQAWMRAQPGAKPMLACVMNLSERRADVLQAVPGIVITESMRQLLGKEREVSH
AYASARSLARLALQIVGLQWMGYAGVHLSGVHTLDELLLLEQAIIEQRGKVTSLADWSER
WQAGWRLPGAPEVRFTPGIDAWTLGQADVVATRRERLRYALLATVHEQFFDRAGWFSRAF
GWSVTRPLWQAGVAANALRAVERTIKRPLVGCDTCGSCRLQDTLYVCPETCPKGLANGPC
GGTRLNRCEFGDRECVHSVKYRIAKSTNQLPALAQTLIPGVEAQDRHRSSWPEWFKQEDS
APGS
>A0A6I3M8H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces bracchium|TrEMBL
MTGTEPDGAAARPRVPISFELFPPRTDAAAIALGRTIDRLAEVDPAFISVTFGAGGSSRD
RSLTVLRYMLEHTRVEPMAHLTCVGSSHAEANRLVREFLDAGITSFLALRGDPPAGAADA
EDAIGDLHSAAELVQLIHRVQEEREPFGQSRIPGMPGVTAIRERPRPERVAVAAFPTGHP
RSRGSNQDVDVLLAKEVAGANLAITQLFWHADDYLTFVQRARAGGVTIPILPGIMPVTTP
ARLARLEQLTGVPAPAELAIDLEIEPDADAQFELGVDYASNLAADVLAGGAPGLHLYTFN
RHEAVLAVLDRLGLATAPAHAGTERNTRER
>A0A7K3B343|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8377|TrEMBL
MALGTASTRTDHAVTIRELLASGERSYSFEFMAPRTEKGERTLWNAIRRIEAVGPTFVSV
TYGAGGKSREGTVRATERIASDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLALR
GDPPGDPMGEWQRHPEGVDYAYELVRLIKESGDFCVGVAAFTEMHPRSADWESDTRHFVD
KCRAGADYAITQMFFNAEDYLRLRDRVGKAGCETPIIPEIMPVTNVRQIERFAQLGNAPF
PQELADRILAVKDDPAAVRAIGVEYATEMCRRLMAEDIPGLHFITLNHSTASLEIYENLG
LHQRS
>A0A8H5ICG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium napiforme|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLSRLDAVKGDDERVKMVGVDIVSELVDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLSSDSSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A7N8WXK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mastacembelus armatus|TrEMBL
MVNQVQRDGGSWQSCKSDSSGASNSGGESSKESSRCSTPVLDADRADRLRDKMRRRMDSG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPSGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPMGTDWEEEEGGFNYAV
DLVKHIRSEFDDYFDICVAGYPTGHPEAQSYEQDLRHLKEKVDAGADFIITQLFFRADTF
LKFLDDCRANGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIHQAVEICRVLLDSGKVPGLHFYTLNREVATIEVLRQLGLWKEDPRRPLPWAISAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLQMWGKELMNEDSVYEVFTCYITGQPNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSADPIVGWGPAGGYVFQKVRRLLDLFCVCGQVVLLPHVLMSPIV
CLCVSGRNLTNAPDLQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIKYIHDNYFLVNLVDNDFPLQSCLWQVIDDMFELLDAPTEPLRDITV
>A0A4U1AAP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila sp. IMCC35006|TrEMBL
MKEGEISVIHNFNDDISTPDKFVVTLELVPGRESSGRTIDTITGIAREAQADGRITAVSI
TDNPGGNPALSPDALGHEILNDGMDVIVHFTCRDTNRVGMESRALQLAHMGMKNILALTG
DYSGKGFGGAGLPVFDFDSVILTSMLSSLNKRLIRAGHASIFVTGCAVSPFKYTEAEAWI
QYKKLERKIEAGASFAITQLGYDIDKYEELLLYNKDKKIEVPVLASLYVLDKRSARPMHA
GRIPGVHVTEKLYNKVMQEWEGAGEGMQHAIERTARLGVVLKGIGYKGIHLGGIHDSFAT
VGKILDRMAAIEHNWLDYLDEFREDEPNRFYLYKQAETAKSVIPGKETIKVKLTDNFHYL
FLRTAHELFFDKRAALAPMYKKISNSLDKSNTSWLLKVFLEDPFKKVMLSCKSCGDCGIQ
HVGFLCPESGCPKHTRNGACGGSNNGFCEVNTDKLCVWVRAYRRMKKHGETDKLTREFVP
PRLWELKDTSSWINFHLERDHQKPVKPPARTL
>A0A285UJ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium subbaraonis|TrEMBL
MTIAHSPARRRAPKLSFEFFPPRSEEADAQLWQTVDALSAYAPDFVSVTYGAGGSTRGPT
LSTIGRIIRDTPLSAASHLTCVGATREEVDAVVEEFRQVGVTHFVALRGDPAGGIGEAYQ
PHPGGYANAAELVAGLRSIAPFEISVSAYPEKHPESHDVPADIDMLKRKVEAGATRALTQ
FFFDNDLYARYLERVRAAGIDIPIVPGILPVHNLSQVQKFAGLCGASVPQWLADRLEPLA
ERPEERAAVAAELAARQIEGLIALGVDEFHFYTMNRAALVSAVLDRLGFEQRDANCAGAA
TGAAA
>A0A1C5VBZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Megasphaera sp|TrEMBL
MRTNELFAKKTVFSFEVFPPKPDTPIETIYAALDELSQLYPDFISVTCGASGSGSGGNRT
VEVASAIKHTYGCETAAHMPCIYLTEDDALRTLDELKKAGIENILALRGDETPGRERAHV
FEHASDLVAFIKQNAPEFNVIGACYPEGHTEAQTMAADIRNLKTKVDAGASELISQLFFD
NATFYRFLERCEIAGISVPIEAGIMPVTNKKQIERMVSLCGATLPVKFQRAIAKYGDNAE
AMRDIGIAYAIDQIADLLANGVDGIHVYTMNNPYIAKKITEAVKNLL
>A0A2N2JVI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-15|TrEMBL
MKLKEALEKKKFTVTSEIQTPFDEDPASLMKALESVRERVDGFSVVETEINGVVGDSIKI
CKELQNNRFEAVYRTTIRDKSRPQLLKDLALAHKSGVENILTFTEFYRISGDSLQEMMFF
HVDSGKLQSVLEHLSEGRNVDGHELPSKASFLVGAGVDSRWGSDVPSMELKEMESMRELG
TGFFLTTPVFEIDRFEKFMRQAKQIGVPVIAEVMILKTAGMGSFMNRHVNPNMVPEHVIR
KLAKSTDRQKSSIEIFAETVKGLKEICQGVHIITIGAESKLKLYLDAAKLY
>A0A439F384|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp. UYMSc13B|TrEMBL
MQDRYYSFEFFPPKTAEGTEKLRNTRAQLAALKPKYISVTFGAGGTTQQGTLDTVLEIQR
EGIEAAPHLSCVGSSRESIRDILKKYRDGGIRHIVALRGDLPSGMGEIGEFRFANELVEF
IRAETGDWFNIEVAAYPEYHPQSKSPRHDLENFVRKVRAGANSAITQYFFNADAYFRFVD
DVRAMGVDVPIVPGIMPITNCSQLMRFSENCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>K6YV10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraglaciecola arctica BSs20135|TrEMBL
MASYAQGIDALNQSLSEVQGIDVSFEFFPPKTESMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQAETGIQAVPHLTCVDATREELIEIAKDYWQSGIRKIVALRGDLP
DGVEKPQSYASDLVTLLKEVADFEIAVAAYPEKHPEAPNSQFDLLNLKRKAEAGATEAIS
QFFFDAEVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLQRFAGFTNVHVPQWLHKMYDGL
DKDDQTTRNLMGANISMDMVKVLAKEGVRKFHFYTLNRSELSYAICHMLGVRAD
>A0A2M9HD64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium simiarum|TrEMBL
MHSPQFSLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRSATARIANTVR
SEYGIPTVAHLTALYSDHEVVDQALEMFDAAGVFGVLALRGDVIEGQQEVGEFEHASDLV
AYIRDRRPNLKIFGACYPEGHIECPSLDEDIRNLKIKVDAGATNLISQLFYDNEDFLRFV
EKTRAAGIDVPIEAGIMPVTSAVSVRNMARKNATVIPKALNAMLEKWGDDRESLRRAGII
YASQQISDLVAQGVDGVHLYTMNHPGTTRRIWRNVAPLFREV
>A0A419WKP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinifilum flexuosum|TrEMBL
MKVIEHLNQAIENKTTHFSFELLPPLRGNSIYKVFNTIEKLRGFDPKYINITAHRDEVVF
VESPNGGFEKKITRKRPGTVAVAAAIQNKYKLTVVPHVICSGFTPEETENALLDLNFLGI
HDLLLLQGDKSPRHDFIPSEGEHKFAIDLIGQVNGINKGNFLDGTHVEPFETPFSYGTAG
YPEKHENAPNMESDLYWLKKKVDAGADYIVTQMFFDNQKFFDFEKRVREAGITVPIVPGI
KPISALSQLNVLPQIFKTEIPEALAAEVRKCKSNDEVKQVGVEWGIQQSKELIQHGVPSL
HFYTLMASNCVRDIAKAIY
>A0A161VQ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labrenzia sp. OB1|TrEMBL
MSESSSRRSHQAAASPITASFEFFPPKSEKMAETLWNTVQRLAPLEPSFVSVTYGAGGTT
RERTHKTVERILRETDLAPAAHLTCVGASKEEVDAIVRDYWALGVRHLVALRGDPLEGIG
TRYVAHEKGYAYASDLVAGIKKIANFDISVSGYPEKHPESGNWQTEIDNLKRKVDAGADR
IITQYFFDNDMFDAYLDRIAAAGINIPVIPGIVPIHNFEQTMVFSAKCGTSIPQWLARRF
AGLANDPETRKLVGVAVACEQVMDLVDRGICDFHFYTMNRADLTYAICHMLGMGKPVHED
MAA
>A0A0G3AS37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces incarnatus|TrEMBL
MALGTPSTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPTGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVTHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPRLSNAVF
PDALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A399VA66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nakamurella silvestris|TrEMBL
MVTVRDRLSAPGLHISVEFYPPRDDAEEGVLWHAIRRLEPLQPAFVSVTYGAGGSSRDRT
IRVTERIARETTLLPVAHLTAVGHSVTELRHVIGSYAAVGVRNILAVRGDPPGDDPLADW
VAHPEGLDYADELVTLIRSLGDFSVGVAAFPGMHPRSADMETDTRYFVGKVRAGADYAIT
QMLYTATDYTDLRARALAAGADVPILPGIMPVTSYGRLRRMQDLSGQAAPLELAERLRAV
DGDTKAGYRIGIDHAVAMCAELIEAGAPGLHFNTFNRSRATVDVLSELGLVDGAASAAGV
AVATG
>A0A1T4Q128|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella oulorum|TrEMBL
MNVIDIIQQHKGHNNFSFEVLPPLKGYGTANLFATIDRLNMLHPLYVNITTHHSEYVYRA
LENGQFERNRVRRRPGTIAIAAAIQNKYQLPVVPHVICSGATAEQIEYELLDLQFLGIEN
LLLLRGDKAKDDRVFTPVPGGYCHTTELISQVNRFNNGQFLDGTSMKHPGHPFTYGVAAY
PEKHDEAPNIALDLQYLKAKQEAGAQYAVTQLFYDNSKFFTFVEQARAQGITLPIIPGIK
PFARLSQFTVVPKTFHCDLPEALAHEVLKCKTDEDAKQLGIAWGVEQCKELYAAGVSNIH
FYTVSAVESVYEIAKQLV
>Q5SNW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Homo sapiens|TrEMBL
MDHRKARVLPAGHYCPSLGIWASQVGSVRSSVPPSIRNPAMVNEARGNSSLNPCLEGSAS
SGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISRF
DRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRLEEITG
HLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDICVAGYPKG
HPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPIQ
GYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHF
YTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVLYLS
GEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLVN
LVDNDFPLDNCLWQVVEDTLELLNRPTQNARETEAP
>A0A2T5HMP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GV071|TrEMBL
MSKERRYSFEFFPTKTDAGHEKLMATARVLAGYNPDFFSCTYGAGGSTRDRTINTVLQLD
SEVKVPTAPHLSCVGDSKAELRALLKQYQEAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRKMGVTIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDIDSIQSYG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1N7NQ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Insolitispirillum peregrinum|TrEMBL
MTAPNSSPASASSPVRVSFEFFPPKTEKMQESLWAAIERLAPLAPSFASVTYGAGGSTRE
RTHDTVTRIQSETGIPAAAHLTCVAATRDEVNAVAQAYWNAGIRHIVALRGDPPEGASRY
QPHPGGYPFAVDLVRGLKEVADFEISVAAYPEMHPEASSPQADLDNLKAKIDAGATRAIS
QYFFDIDAWRRFRDRVAAAGITVPIVPGILPVTNFAQVQKFSAACGTTVPAWLADRFEGL
DDDPETRKLVAATTAAELCEALRADGEQDFHFYTLNRADLTFTICHILGVRPPKKTA
>D4FRH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis ATCC 35037|TrEMBL
MTLTDQGTAWPSWLSNHEIKKKRIMTMSRQTPSLSFEVFPPNPAVGNDKIISALQDMREL
TPHFISVTASNNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVG
VQKILALRGDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQ
NLKKKVDAGCSSLVTQLFFDNERFYDFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTC
ENIHLPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYI
HQATHALFNHQSLG
>G2HCS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp. A2|TrEMBL
MKIRDRIAASTSPFYSLEFFPPKERENWPGFFTTVERLKALNPLFASVTYGAGGSTQDNT
LEITSYLKNVMGLEPMAHLTCVGATRERIADYLRRLREVNVDNVLALRGDAPKGQDFDWD
TAEFRYAADLVRFTRSEQPDMGVGVAGYPAAHPESPSFASDLRHTADKVNAGADFIVTQL
FFDVREYFDFVERLRGLGVDKPVLPGILPIQSLESVRRILSLCGANIPGNLYLELEAANE
KGGAEAVKEAGIAFAQRQIRTLLDGGAPGIHLYTLNRADTCLRIAEAVGMK
>B0N2P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelatoclostridium ramosum DSM 1402|TrEMBL
MKIIDLLHRRPTLSFEIFPPKNHDGDISSIYQTIDELAKLKPDFISVTYGAGGSTTENTV
EIASKIKNEYSIEAVAHLSCIDATPEQLIRVLDSLKANNIENVLALRGDYPRGYDPMKAP
HYYKYASELNDFISKNYPDTFCLSGACYPEVHQEAASLEEDLIALKKKVDAGAEYLITQI
FFDNNYYYRLVREARIRGINVPIIAGIMPATNSKSLLNIAKLSGCNIPYNLSASIERFKS
NPQAMKEVGMNYATNQIIDLITNGVDGIHLYTMNKPETVHEILKRTSNILAEFKND
>A0A094B771|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4513|TrEMBL
MADSPTTDKITDKIAALPQDANYFSLEFFPPKTAMGSTNLRARLDRMARALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSRALVDQALSAAKEAGIQNILALRGD
EPRGEYKDALEEGKDGEDEFVWAIDLVKYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
VHDLPYLVDKVQAGADFIMTQLFYDVDAYDNFEKVLRDHSSGAFKTIPIIPGLMPIQSYQ
ILRRTTKLSNARLPESIINRLDAVRSDDEMVKRVGVDILAEIVESVKHTKSRTKGPKGFH
FYTLNLEKAVAFILERANLIPSFTPVITSDVFAVDDITDTIPLPQLLINGEKKTRRQSSV
GSGPHNFVIIDREEASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRSDISSIFVQYLSGNLSALPWSDE
PITAETNLIKNELVKLNQKGWWTIASQPAVNGERSQDGVVGWGPKGGWVFQKAFVELFVP
TSDWARLKPLLESNEEVSFLAQSASGEFLKSKLDLGPGEEGSETNAVTWGVFPGKEIVSP
TIVEEVSFRAWAEEAWQMWAEWAAVFGKSGEESRRFLDGVSRDGWLVNVIWHDFVGMCKA
KEGRSEEPGEGEVVENIVGREGGSTPLAESSRMIQDPAGLAGAMVRRHTWKIAVN
>A0A1I0CLC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] polysaccharolyticum|TrEMBL
MNIADMFKEDRTVLSYEVFPPKGDKPIESIYDTLDELGKLRPDFISVTYGAAGNVANTDT
IDIAGYIQKKYSIQSIAHLTCVHASFENIDRILGDLQSRGVDNILALRGDIVKGMEPKKD
FLHASDLAKYIMDKGGFHVSGACYPEVHQDAKNAIEDIKNLKIKVDAGVNHLISQLFFDN
TVFYHFVEKARIAGINVPIEAGIMPVTNRKQIERMVTMCGASLPTKFVKVMQRFDGNPEA
MRDAGIAYAIDQIIDLVANGVDGIHIYTMNNPYVARRISEGVESIVRGRA
>A0A1B1EFG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio natriegens|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSNEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKSETGLVAAPHLTCIDATREELIEIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVVAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAV
>A0A2U2NBF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium callitrichidarum|TrEMBL
MHTPMFSLEVFPPKRNAPVGTIYDTLDGLEGLDPDFISVTYGHGTHTDRTATARIANTIR
QEYHIPAVAHLTALYSDKAKVDEALDMFEQAGVEAVLALRGDYIEGEKTVGVFPHASDLV
AYIRERKPELKVFGACYPEGHYQSASLDEDIEHLKIKVDAGVTHLISQLFYDNDDFYRFL
DKARAAGIDVPIEAGIMPVRGAKSVRRMAERNASRIPDHLAAMLDRWEGNAEALHAAGIA
YASQQIADLVAHGVDGIHLYSMNHAATTRRIWRNVEPLFTVD
>A0A1Q4URC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira sp. TSL5-1|TrEMBL
MRVSFEFFPPKTEKMEETMWRSIHRLAPLAPSFVSVTYGAGGSTRDRTHASVTRIQRETG
IPAAAHLTCVGHTRDEIERIARTYWDEGIRSIVALRGDLPDSGDTYIPTPGGYDYAVDLV
AGLKQIADFDISVSAYPETHPDAPSADFEIEYLKRKFDAGANRAITQFFFDNEVFLRFRD
KCAKAGITAPIVPGILPVTNFAALLKFADMCGAQVPARLHHRFDGLDEDPETRRMVAFHE
AISQVEGLIAEGVEDFHFYTLNRAELTYAICHALGIRTKQVALSA
>A0A2V7Q5L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYSKGFYLNVCYDELNLKHPKLVQEVHEAYVRAGAEILETNTFGANPVKLGSYGLA
EDTEKINQAAAELARRAAAGHASVAGAIGPLGVRIEPFGATSREEAFAHFQRQARGLVAG
GVDGFILETFSDVDEIHEALRAVRSVSDLPVIAQMTIGDDGLTHYGTGPETFAKQLAAWG
ADAVGVNCSVGPAGVLEAVEKLVKATDRPISAVPNAGLPKDIGDRKIYLASPEYMASYAR
RMIEAGARFVGGCCGTTPEHIKKIRDYVASVVPRHQPAVVSREAIEPPAGVEEVPLAARS
CWGAKLARGELVTSVEIVPPKGVDPTPMLEQCRALKAAGVDAVNVPDGPRAQSRMGVLPS
AILIEKEVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLTNLVYRLNHGLDPGNNPIGAPTQWAIGVGVNPGAVDLDRELSRFAWKVDAGA
EFAVTQPVFDPKQLEAFLARVGQFKIPIVAGIWPLLSLRNAEFLANEVPGVSVPESVLAR
MRQAQDKGKEAALAEGVKIAREMFEQVKGTVQGVQVSAPFGKVEVALEVFH
>A0A350Q8P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MDGAMGTELYASGVFVNVSYDGLNLETPDVVETVHRNYVNAGAEVIETNTFGANPVKLSS
YGLADRTEEINHAAVGLARRSAQGRTLVVGAIGPLGIRIEPLGPTSREEAQEFYKRQVDG
LVEGGVDGFVLETFSDLNEMEQAFKAVRSRSPLPVICQVTVGDDACTSYGTSPEDVATEV
ASWGASVIGLNCSVGPAVMLEAVERMAEVTDLPLSAQPNAGLPRAVGDRKIYLASPKYMA
QYARRMIEAGARFVGGCCGTSPEHIRSIRALVGGVRPPSTRVRPGSHAESHDTPIQPEVP
LGERSVWGRQIAEGTFVTSVEVTPPKGWNAEILLGQCRRIQAAEANTVNVLDHPHAHTRM
SALPAAMLIEREVEIETIVHYPCRDRNMTRMISDLLGAAAAGLHNLLLVTGRPPAMGPYP
DSTASLDIDSIGLTNVVHGLNRGVDPGGNAIGVPTRFVIGVRVSQVAVDQDREAGRLNWK
VDAGADFVITRPVFDAERLHSFLEHVPELSVPIIASLRPLTSLREAEFLHNEIPGIQIPD
RVLARIANAEAHGEDAARAEGISIAMEAFAAVRDSIAGVHIHVADGNLDGALELLSEIRD
SA
>A0A7X4CLV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
ASVRDGQVQLAVMPNGGEFRRVGHRYLTGVNPECMGRFAREMANKGVRLIGGCCEVHPPH
IHEMHNYLHGLAAGKRIVQLARTPDQQPTDATAKRRNGPFSRKLIDGQFAVSVELLPPRG
TGGLKARLAFVAELAASGLADALDITDGSRGIPLMPPGDFIHLIRRRLHWERDRLELIPH
CTCRDLNVMGLQSRLIGYWANRIHNVLFITGDPPKMAPTYPRSTAVFDLDSTTLIRYAHA
FLNAGLDFGGQPLGTHRDPRTHFTIGTGCEPEALDLQREWERLAHKIDAGADYVMTQPTF
DGKALAALTTYRAQVPIIVGVMVLRGLEHARRIAEVPGVVVPEAIFAELDAYADPADQAK
AGVELAAEQVRQVRAEGWSGLYLMSPAGHQSVLEVLKRGLD
>A0A2D5ZIX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MHDSFLDTLGRRPVLWDGAMGTMLYNRGIFLNQVFEELCLSRPKLIRQIHLEYLDAGAEV
LETNTFGANRLRLRRSGIESKVNEINAAAVEIAQECSAGRAWVAGAIGPTGRVPSVSTDA
ELDELREAIEEQAVALAGAGADLIVLETFRLLSEMRIALKAVRETTSLPIVAQMAFDEDG
KTGDGADPEKVVELLREWGADSVGCNCMEGPQLSFELAGRMVDRGLPISVQPNAGYPRKV
DERLLYMVTPEYFTEYLRRCLKIGVAMVGGCCGTTPEHIRHASGATRMMGGGRILVSEKT
SSPTEETTQEQSPLPLEERSALGAKIEQVFRTRVRGSEPGRIDPSSFCVSVEIGSPFGLD
MEPAIAAARLLQASGCDAVNIADGPRATVRVSNSVLASVIEEQVGLATILHVCSRDRNLL
RLQSDLLGGSVSGLHNLIIITGDPPKVGDYPNASAVYDVDSIGLLKLAAGLNRGVDPAGR
GIGSRTSFVLRCGAEPAALDYDREIRRLEEKKKAGAEFVMTQPVYEAELIHRFLDDIESL
DLPVMVGLLPLASFKNATFLHNEVPGMQIPEAILSRMEKVGRGRAARAEGIAVAQEALDA
VKERVVGAYVMPPFGNYRAAVHVLEGVGYELP
>A0A2V7FZU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTITLSDLLKDGKVHVLDGAMGTMLYSKGFLLNVCYDELNLKQPKLVQEVHEAYVRAGAE
VLETNTFGANPVKLRSFGLADETEQINQAAVRLARAAAAGRASVVGAIGPLGVRIEPFGA
LARDEACAHFSRQVKGLLAGGVDGFILETFSDVEELHAALRAVQGLSDLPIIAQMTIGDD
GLTHYGTGPETFAQQLTEWGADVIGVNCSVGPAGVLEAVEKMVKVTDRPISGVPNAGLPR
DVGDRKIYLASPEYMASYARRMIEAGARLVGGCCGTTPEHIKKIRDYVASVVPRHQPAVV
SRETIAVPAGVEEVPLAARSRWGAKLARGELVTSVEIVPPKGVDATPMLEQCRALKAAGV
DAVNVPDGPRAQSRMGVLPSAILIEREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRN
ILIITGDPPKMGPYPEATAVFDIDSIGLTNLVFRLNHGLDPGNNPIGAPTRWAIGVGVNP
GAVDLDRELSRFAWKVDAGAEFAVTQPVFDPAQLEAFLARVGQFKIPIVAGIWPLISLRN
AEFLANEVPGVSVPESVLARMRQAQEKGKEAALAEGVKIAREMFQQVKGSVQGVQVSAPF
GRVEVALEVFG
>A0A2V7L1E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MPINLRDLLADGKVHVLDGAMGTMLYSKGFYLNVCYDELNLKQAKLVQEVHEAYVRAGAE
ILETNTFGANPVKLSSYGLADDTEKINQAAAELARRAAAGQASVAGAIGPLGVRIEPFGP
TSREEAFAHFQRQARGLVAGGVDGFILETFSDLDEIHEALRAVRSVSDLPVIAQMTVGDD
GLTHYGTGPETFAKQLTDWGADAVGVNCSVGPAGVLEAVEKLVKATDRPISAVPNAGLPK
DVGDRKIYLASPEYMASYARRMIEAGARLVGGCCGTTPEHIKKIRDYVASVVPRHQPAVV
SRETIKSPAGVEEVPLAARSCWGAKLARGELVTSVEIVPPKGVDPAPMLEQCRALKAAGV
DAVNVPDGPRAQSRMGVLPSAILIEREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRN
ILIITGDPPKMGPYPEATAVFDIDSIGLTNLVYRLNHGLDPGNNPIGAPTKWAIGVGVNP
GAVDLDRELSRFRWKVDAGAEFAVTQPVFDVRQLESFLKRVEAYRIPIVAGIWPLMSLRN
AEFLANEVPGVVVPAEVLERMRKAQDKGKEAALAEGVKIAREMFEQVKGTVQGVQVSAPF
GRVEVALQVFG
>A0A4P5WHV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MPSPFSVSFEFFPPKTPESEEALWRAITRLAPLSPKFVSVTYGAGGSTRERTHRTVKRIL
AETELVPAAHLTCVGSTQSEIHEIADAYWESGVRHIVALRGDPSTAGAGYEPTPDGYAWA
SDLVASLKARHDFDISVATFPEGHPEARSLDAELDNLKRKIDAGATRAISQFFFDHGTFL
RFVDRARKAGITVPIIPGIMPVTNFGQMTKFAEMAGATVPSAMALMFDGLENDVETRKLV
AVTIAADLCQKLADAGVKEFHFYTLNRADLTYALCHILGLRPVR
>A0A250I6B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melittangium boletus DSM 14713|TrEMBL
MKIRNRLNPSDPCFSFEFFPPKTDAGTANLFQTLEELAPLEPGFVSVTYGAGGSTRDRTV
DLVTRIKRDTGIETMAHLTCLGHTRDELRDLLRRLQEARIDNVLALRGDVPQGAPLVAPE
DGGLRHASELVRFIRDEDFNFGLGGAGYPEGHVEMGSRDEDLRHLKAKVDAGLDFVITQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQIQRFTRMCGATVPMRLTLQLERLKD
QPEALVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVSALRART
>A0A7L8RR95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter sp. SR38|TrEMBL
MRLSVTRSDLDEAIGALVGNFSIEALPKDTQKFDDLRDHLPVGTRVYVAYTSGSTAEIVD
AAEKLRHQGMEPVPHIPARRFASHDELKGFLGKLAARAAVKQVLLVGGDVARPEGPYAAS
LDVLRTGMLEGHGIEAIGLAGHPEGHPGVAREALRNALIDKCEYAAKVGLDVSLVTQFLF
DTDKLFAWHADFVENAAPGIAVDVGLPGLAKMTTLMRFAKDCGVGASFGMLTRHAGRAFK
LATSFSPEDTLLELADGVRKSGRPIFRSVHFYPFGSFEKTAEWLRGLQSQRPARGQPHLA
EAL
>A0A7Z7FFJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanolobus vulcani|TrEMBL
MSRTFKDKLTSNDFLITAEVSPPKGTDLAEMLSDAELTRGWVDALNVTDNQKAIMRMSPL
AVSKALLDSGHEVIMQLTCRDRNRLALQSDLLGAYSMGIRNICIMTGDHTTKGDHPKARP
VYDLDSVQLLNIIRKMQEGLDLAGNVIDNPPQFVVGAVTNTDPSKKAQMMKLRKKVKTGI
DFMQTQAVYDISMFEDFMESIGDIEVPIIAGVIPLRSANMARFMNGNIPGISVPDEIIER
MDSAERPMEEGVAICAEAIKELQKLCRGIHLMPIGKHNNTPTILELADIRKK
>A0A1I4DRD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loktanella salsilacus|TrEMBL
MTHPKISFEFFPPKNLEGSFRLWDCVNVLAPLAPEFVSVTYGAGGTTRKLTHEAVTTIDK
TTGLKVAAHLTCVDATRAETLAIAEEYAAAGITDIVALRGDAPKGSEKFTAHADGFASSV
ELIEALSATGKFTLRVGAYPEKHPEAASQDADVEWLKRKIDAGAAAAITQFFFEADTFFR
FRDKCVKAGINAPIIPGILPVENWKGASKFALATGTSIPPVIAQAFENALRDGNADLLAT
ALATELCDDLLQGGVDHLHFYTLNKPQLTHDVCRALGIAPQPRLQNVA
>R5V643|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:254|TrEMBL
MSSPNKTTFSFEIFPPKPTSEPSVIYGTLDALQDLKPDFISVTYGAGGGANCKNTVGIAS
YIQNTCQTESVAHLPCLYLSESDLNGILEQLQENGIHNILALRGDRSETATPNGRFSHAN
ELISYIHDYDPSFHIMAACYPEGHPEQHSPAEELETLKRKVDAGASQFITQLFLDNDAFD
TYRNKVAQAGVSVPIEAGIMPVTNKKQIERMVKLCGATLPKKFLHILNKYEDNPEALRDA
GVAYAIEQIVDLIAQDVDGIHLYTMNRADVARDIDHAVHRLLQ
>A0A3B9DQ31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
PPSTRARPGSHAESHDTPIQPEVPLGERSVWGRQIAEGTFVTSVEVTPPKGWNAEILLGQ
CRRIQAAEANTVNVLDHPHAHTRMSALPAAMLIEREVEIETIVHYPCRDRNMTRMISDLL
GAAAAGLHNLLLVTGRPPAMGPYPDSTASLDIDSIGLTNVVHGLNRGVDPGGNAIGVPTR
FVIGVRVSQ
>A0A3G6N929|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium indoltheticum|TrEMBL
MKITDHIKNANGKALFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTLGGHASAMDLVNQINNLGRGKYLHNDEQICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVTKAREMGITVPIIPGI
KPIATKNHLKLLPQVFKIDLPEDLINAVEGAKNNEAVKQIGIEWAISQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A1G8KQC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio sp. 49|TrEMBL
MKISELYKKDRRTLSFEIFPPKREENLKNIDETLSVLCELKPDFISVTFGAGGSANSNNT
IAIAKKIKNDYGIEPVVHLTCLSYDKHEIDEFAKILEYEGIENILALRGDKNERLVAKED
FKHSTDLISYLKHNHDFCFLGACYPELHPESTGIAGELSGIKSKVDAGAEVLLSQLFFEN
EAFYKYNERCKNADINIPMIPGIMPVINAAQIKRMVSLCNASFPERFQRIISKYENNKEA
LFDAGMSYALSQVIDLLVNDINGIHLYTMNNPRVARRICEGIKNII
>V9VST7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leisingera methylohalidivorans DSM 14336|TrEMBL
MDHTLPQPYSAPPEGHVSHSRLERVLRSGRFAITAELNPPDSADPADVYDAARPLGEVAD
AINATDASGANCHMSSIGISALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAAMGVSNVL
CLTGDGVGVGDQPGAKPVFDFDSLSLLRTIRTMRDERKFLSGRTIKNPPLLFLGAAENPC
IPPYEWRPERLAKKVEAGAEYIQTNYIYDVPLFEKFMARVRDLGLDKKVYILAGVGPLAS
ARAARWMRSNVPGIHVPDAVIDRMEKAEKPGQEGKKICVELIQQMREIAGVSGVHVMAYR
KEHEVSEIIRASGVLASRKR
>A0A5D0PE60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea sp. PA05|TrEMBL
MPFELICEIEPPTKPDLKHVRHQIGTMSKIAHGFLIPDNHIGRATVSSVAVAHEVEAMGG
RGIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTSGNRTSDLTVRSMIEEARDF
SPAFRVGAAAGLRPLPAWKRTADFLFSQVSFSVEEQLRWREEHPVEVPVYAGVMVLASER
HARTLAAAIPDIALPERLVEAVAADRMAGVEAACEQVLALRDTGAFAGVHLVPVARYRDV
ESRLAAAL
>A0A1X7CSN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio gilichinskyi|TrEMBL
MNVASSIKEVGQFFSFEFFPPKEKQAWDNFMEKAERLADLRPLFASVTYGAGGSSHENSL
DVCETLKKEMGIDILAHLTCVGASEHSIDDFVSRLKDAGVSDILALGGDGRCEEGNNESR
FLRAADLVDYVESKFSDVGIAVAGYPSGHPDSPTIAQDINYHCDKLSKGAEFTITQLFFD
NRQYFDYVDRVGDMGFDQPVIPGVLPIQSLGSLRRIMSLCGASIPGDLYCGVEKAFKNGG
DEAVMEFGFNFAQNQIAGLLKGGVPGVHIYTLNRAAMCERLIGSLKSDGYFA
>A0A317N4C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia neocaledoniensis|TrEMBL
MVQSLRTHAGSGVPFSVEFNPPRDAAGEARLWRAVREFECMHPAFVSMTYGAGGSTKDRT
VRITGELATETTLLPVAHLTAVGHSLDELRALVGSYADSGIRNLLVLRGDPPGDPLGEWR
KHPEGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLDHDTRFLAAKLRAGAEYSITQ
MFFDVDHYLRLRDRVVAMDPVEGDKPIIPELMPITSLRTVARAEELCGRPLAPAVLERLT
KAAGTGPEEDKAAVRAEGIQIATEMAQRLIDEGAPCLHFITLNFAKATSEVLTNLGYGVT
AAPLSA
>Q1R3X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli (strain UTI89 / UPEC)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A380MJ79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Suttonella indologenes|TrEMBL
MNKTAVLQLIQDFSIETTPRGLSKLAPLAQYLPAQTRVFITFLPGAAFADTVRSAQEIAA
QGFTPVVHVAARNLQSQAELQEGLEALQAGGIRDLLLLAGGSIHTRSPFQNALEILDSGI
LEPFDWRSIGFAGHPEGHPDVQAEELRRALEIKWQYARQYPREYYLATQFCFQAEPVIAW
RQSLLAADIHFPLRLGVAGLANTAALIRHAQLCGVGPSINFLIKNAGVFRRLLGGVAAPG
RLVADLAQAVQDGSIDEDVRLHFFPLGDFSRTTAWIAAIQAGKFYLDNQQGVHIEQ
>A0A562NQA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sulfuroxidans|TrEMBL
MTTPAVSFEFFPPRNLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HCGLNVAAHLTCVEATRAETLQIVQDYADAGITEIVALRGDAPQAQAKFAPHPDGFADSV
ELIAAIAERGDMTIRCGAYPEPHPDSPDTAADVAWLKRKSDAGATSAITQFFFDADTFFR
FRDKCAAAGVRAPIIPGILPIQGWAGARRFAERCGTSVPQWAEEAFAQAGKEGEARLALD
VCVNLCEQLIAGGVDRLHFYTLNKPELTLQVCGRLGLHPQNDIDQAA
>R5V8J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:254|TrEMBL
MKIAPLFSEKTVFSFEVFPPKKTSPIETVYQTLEELQDLHPDFISVTLGAGGSGNGENTI
AIARRLQEQYGITSMSHLPCIHCTKEKIDALLETFLESGIENILALRGDRVPELEPEHDF
AHASDLITYIREKHPNFDIAGACYPECHTEATSLEEDIANLKKKVDAGATHLISQLFFDN
EAFFHFQAEARKAGITVPIEAGIMPVTNSKQITRMVSMCGASLPRKFTRIIQKYEDNPTA
LQDAGIAYAIAQIIELLAAGVDGIHLYTMNNPYVARKISEAISGVLRATQR
>A0A7W0J2W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MRIADKLASGANGVSFECFPPKTDAGRNNLYSAIGELKKYNPLFVSVTYGPAAVYPEGHF
ESLSLEDDFFVMNRAESASRIIENAGLI
>A0A7G1QBE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosacidococcus tergens|TrEMBL
MNAQKEKDLIFSCEFFPPRTEKGITKLKEVREQLAVIDPRYYSVTFGAGGSTRDRTFETV
IEIQGSRIEAAPHLSCIGVSRNEIKNTLTTYKQHEVSHVVALRGDLPSGTVGYGDFHYAN
HLVEFIREQTGDYFHIEVGAYPEVHPQAKSAQADLINFKCKVDAGADGAVTQYFYNLDAY
LRFVDSCLGLGISIPIVPGIMPIHHYPQLARFSDMCGAEIPRWLRKRLEDFKEDEDEALL
SFTTDVLSHLCQKLLDAGAPGLHFYTLNRAEPTLAIWHNLGLSTKK
>K0B235|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gottschalkia acidurici (strain ATCC 7906 / DSM 604 / BCRC 14475 / CIP 104303 / KCTC 5404 / NCIMB 10678 / 9a)|TrEMBL
MGTYYSEITGERVSFCELANINNPETIRNIHKEYIDSGAKLIRTNTFSANTITLGVTREK
LKEIIESGYNIAKESTEGRKVFVGASIGPIHESVFKKDDDIDILEEYKFIVDTFLNLGED
IFIFETFGTIDYLKEISEYIKSKNSNAFILTQFAVTLDGFTRKGISINGILDEVKKIETI
DAYGFNCGSGPSHLYKLIKDMDIFDDTISALPNASYPELINERMVYVNNPDYFANIVVDI
SKLGAKIIGGCCGTTPAHIKSIVEKLESNGFKEVEHIKVKEKHKAVFEKKRNNFLNKVED
NKFIISVELDPPYDTSIEKMVDNARICKENGVDIVTIADSPRGIARVDSIMIAAKIKREI
GIDVIPHLCCRDKNLNALKSGLLGAHIEDIRNILVVTGDPILDIDKISTKSVFNLNSYRL
MELISELNKETFKTDKINISGALNLNVKNKELEINRMLKKVEQGANIFFTQPIFHDEVID
FLSKLKKDSGIKIMGGIMPIVTYKNAQFLNNEVPGIDIPKEYVDRFHKDMTKEESEQVGI
ELATEIANKLKDHVDGFYFITPFDRIEMVMEILKKVR
>A0A2H6A100|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR33|TrEMBL
MAPTLRDFLADGKVHLFDGAMGTMLYSKGVFVNVCYDELNLKQPRLVQSIHEEYVRAGAE
LLETNTFGANPVKLAGYGLADLTEEINRKAAEIARKAANGKAAVVGAIGPLGIRIEPFGP
TSREEAREFFQRQVKGLLEGGVSGFVLETFADLEELRQALEAVRSLCDLPVIAQVTVNEE
GRTAYGTDVEAVAARLHEWGAEVIGCNCSVGPAYMLDAVERMAKVTDRPLSAQPNAGLPR
SVGDRKIYLSSPEYMASYARRLVEAGAHFVGGCCGTTPEHIRKMRAALAQIERGKSFPVP
YVSPPVSADGREAVPLANRSKLGEKLASGSFITTVELLPPKGWVPDRLIEQARILRSAGI
DAVSLLEGPRALSRMGAIPAAIIVQRQAGVEAIVHYTCRDRTMLGMLSDLLGAAAAGIRN
LLLVTGDPPRAETAPSQTGIFDIDSIGLTNLVFRLNRGLDPGGNSIGEPTRYVIGVAVNP
WAADLDHELRRFYWKVDAGAEFAVTQPVFEPERLEEFLKRTEEFRIPVLAGIWPLLSLRN
AEFLAHEVPGIHVPEPIIDRMRRAQERGAEFARAEGVAIAREMVEQVRGLVNGIQISTPL
GRVDSALQVLGAEPTG
>A0A1D2RC12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon WOR_SM1_79|TrEMBL
MSQLRDNFGKKFIATGEASPPPGPDMTEYAHEVEEMKHLMDKIEGVNVVDLPGARVLMSS
LGASIYMLQKGVEPIFQMVVRDRNMAALQADLIAGAAFGIENILSLTGDHPACMASDHKG
AKPVYDLDSKDAERPGYERENEFFYWCGNRSDIFAA
>A0A1D2RBY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon WOR_SM1_79|TrEMBL
MPIRSYGMMQYLLTMPGVVIKDKIVNSVKEASDEQKRTGRKGLIEDAGINLCIDLVDEIK
GLGMKGVHIMPVGNVRALKAIVDRL
>A0A8B7R580|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hipposideros armiger|TrEMBL
MDHPIPKVLPAGHHCPSLGRGALEAGSMRFSEPPSIRNSAMVNEPGGHGGPNPRLAGSSI
GRESSNVSSRCSKLPLSPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAPGFISRLD
QMGAGGPLFIDVTWHVAGDPGSDKETSSMTIASVAVNYCGLETILHMTCCCQSQEKITHL
LHKAKQLGLKNILALKGDPVDDQWKDEEGGFHYAIDLVKHIRSKFGDYFDICVAGYPKGH
PDAGSFEADLKFLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFLIQN
YHSLQQLVKLSKLEVPQQIKNVIEPIKDNDDAILNYGIEKAVSLCQELLASGLVPGLHFY
TLNRKEATIEVLKRLGMWIENPRRFLPWAVSAHPRRQKEDVRPIFWTCRPKSYIYRTQEW
DEFPHGRWGNSSPSAFGELKDHDPFYLKSKSPKQELLKMWGEELTSEESVFEVFTHYLSG
EPNWNGCTVTCLPWNDKPLAAESSLKEKLLRVNRQGVLTINSQPNINGQSSTDRVVGWGP
SGGYVFQKAYLEFFTSPQTKEALLQVLKNYEFRVSYHIVNVKGENITNAPELQPNAVTWG
IFPGREVIQPTVVDPVSFMFWKDEAFALWIKQWGKLYDEESPSREIIQYIHDNYFLVNLV
DNDFPLDSCLWQVIEDTFELLSHPPRNDRETEAT
>A0A7V9VCA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexia bacterium|TrEMBL
MSHPFLDRLRNGPLLLDGAMGTMLYAGGAALDECFDALNLTHPERVAEIHRAYIRAGADI
IETNTFGANRAKLEAFGLEGQVRIINRRAAKLAREEREISGAPVLVAGAVGPTGRTIAPI
GLTAPETVRSIFEEQMAALLEGGVDLLILETMGSVVEARQAILAAQAVGDLPIVVLMTFA
EDGRTIGGESPEQVVDELLPLGPAAIGANCAVGPSRTMAVLRRLAAALHASGVADPPALV
VMPNAGWPTHIGGRVIYQASPDYFAGFGREALAAGASVVGGCCGTTPAHVAALRAAFDAG
VSRDDSVQGEEAVVPARPVTDRKLISLEMAAEPVDEPTAVARALGKTFLVSVEIDPPKGF
NPAKALAGAQLLKDAGVHAINVADSPMARVRMSAMTLSYLIQHRVGIETIVHFTTRDRSL
MGLQSELLGAHAVGVRNILALTGDPPSLGDYPDSSAVYDVDSVGLIRVLRRLNEGVDSAG
ASIGRGASFTIACAVDPTKGDLADEARRLRAKLEAGAHFVMTQPIFDLAVWHRFLEVYAA
EWGSSDLGVPVLLGILPLQSTKHAEFLHNEVPGITLTDEARARMREAGAAGRQEGVKMSQ
DLLAQAAPHVQGVYLMPSFGRYEVAAEVLLAIPVPAPA
>A0A7V3BG52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MEASNIRTLLRERPIVADGGMGSLIYQTLGYPPALCIEQTPLTHPETVLQIHLAYIAAGA
ELIQVHSYGANRVKLAPYGLAEKAVAINSQAVKLAREAKEISGKDVLIAGSISPLELLGY
PTETVDAEACHVITEVVQEQARTLEGRGVDLFILETYASLAELTVTIEAVRAQSNLPIIA
QMAFTDDGKTLTGVMPQQAAVHLHALGVDVIGLNCGVGPLTALEVLRAFAPLVDVPLAIQ
PNAGFPRRVGGRTLYPLASPELFSEFAHQALALGARLIGGCCGTTPQHIAAVARTLRTSR
SSQPVIAAPPPPVQVTTHPPEEREGEIVERPPRSSLLQKLQSGQFVVSVQLDPPKGTNLG
RILNAAAHLKASGKVDVVDINSNPVARVMMDSLITAGQVEDKVGMPTIPHVTTREINIMG
LQSLMLGAWGALKIRNVLAVTGDPPQAGDYPEAKGVYEVDAIGLVKLLSNFNRGVDWTGK
SLGTPTQFTIGVAMNPTAEDLAREIERFEAKVQAGAHFVMTQPIFDLEQWESFLTVWGKP
LPIPFLIGLWPLSSYELARRLHHEVPGIVIPEAVQERLRLAGSHAKEEGIRIAEELLAEL
GHRPEVAGTYIICPFNRYELALTILDAVVLPK
>A0A7V5EAY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MEASAVYSNLQKLLMRGEFVVTGECGPPKGADRSVVEKKVQYLKGNVDAVNVTDCQTAVA
RLSSLATCLILKENGIEPNLQMTCRDRNRIAIVSDLFGASALGIRNLLCLTGDHQKFGNF
PTAKGVYDLDSISLIMMVKKMRDEGKTLTGEEIEGKPQFFIGAAENPFADPLEFRHIRLK
KKIEAGCQFVQTQCIYDIPRFKEWMKRVVDDGLHKKCYILAGVTPLKSVGMAKYMATSVP
GMIVPDSYIERLKAAPKDKREEEGIKICVEQIQELREVEGVAGIHLMAIEWEEKVHEIMA
QARLLPRPKVE
>A0A6V6Y9C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium panici|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAIDLVRQINDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFNFVAKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A5P9BBX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. THAF190c|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSNEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELIQIADDYWANGIQSIVALRGD
IPPGGGAPEMYASDLVKLLKARHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A158S8G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. KN65.2|TrEMBL
MTTPIIHPNWARPPLNMVDGYSLEITAKDVESLRAAAPGILPDTPIALTFLPGEDFDARV
AAARTVRELGFEPMPHFSARRITSRDEFERYLAAVTREASVKRSFVIAGDPSEPEGPFAD
SAALIATGEFERNGITAIGIGGHPEGHPNMSNEECWQVLEDKCKAIAARGMAPLIVTQFA
FDADAVLSWLKELRERGIEAPVRLGVPGPAGIKTLMRFAARCGVGASASVMAKYGISITR
LIGSAGPDKLVKALEQGLGKEHGPVRLHFYPFGGLEKTVAWINEFARKN
>E4MSG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga ochracea F0287|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
IMALRGDAMKEQRYFQPTEGGHTYATELVTQIINLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVEACKNNADVKQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A2P9H2X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacter sp. SbD2|TrEMBL
MSDKSVIKSGSNLESVLCSGHFAVTCECGPPKGADVEHLQKKIDLVRGCVDAANVTDNQT
AVVRMSSIAASSILLRNGLEPVMQMVTRDRNRIAAQSDVFGAYALGIRNMLCLTGDHQSF
GNHPMAKNVFDLDSIQLLDVVRTIRDQGTMNSGDPVEGGARMFLGAAANPFADPFEFRVI
RLAKKIRAGADFVQTQCIYDMDRFREFMRMACDMGLDKQCFILAGLTPLKSAGMAAYMNK
NVSGITVPDEIIKRIRGVPKGNQAEEGIKLLLEQIQQVREIPGIAGVHIMAIEWEERIKE
ITERAGFLPRPQI
>A0A497LLP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MAGEKVYSNLMRELKAGKFVFTGELEPGKEGDIDSTIEAAKSLMGHVVACNVTDNPQSFG
CVNSLAAAYTVQTKTGMECICQLRCSDKNRLALLSDVLAAGLLGIKNILSITGDYVSLGD
TPDVRPVYDLDSTLLTYMIRRVVDEGKDLRGGEIRNPPKLHVGVAANPGSEFLDMEAYKL
KRKVLAGAEFVQTQVVYLPEVVDRFFNKVKEVGVDIPILIGIFPAKSYAEAKFFHEQVSG
VTVPEDFLSKLKQSKEIKDKEKRKELIDQINIEYFTGFLEHLKSTPAAGCHIMAVGYPEI
IPELKKVVG
>A0A7J2JX95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MAGGPAYSLLMKNLRAGRFVYTGEAEPHKTTDISDLIEAFKALKGWVVAINVTDNPTAYA
YMSSLVASYLIQHETGIEAIYQITCRDRNRLAITSDLLGAYALGIRNILALTGDHPCVGD
NPQAKPVYDLDSTTLLYLIRRMVDEGIDLAGNKIEHPPKFHVGIAANPNADPIEPELLKI
ERKVNLGAEFIQTQCVYDIEVAKAFLKEAERWKIPVLIGITPFKSVGMMKYMIKYVPGIK
VPKEIQERIIEAKKRGGKEAVYEENVEIFTEMIKELKRTTRLAGCHMMAVGFEWIVPRII
ERVEGGKPSYMESL
>A0A497F1D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Verstraetearchaeota archaeon|TrEMBL
MITAKRKPLSEIISMIEGHKNVLLLACDGCVGIYDVGGLKQAEALKLELELAFRSKGKEP
PNFTTATVLRQCDTEILKDSISEQVSKVDAVLSLACGVGVQTVAHVFPEVCVYPANNTAF
LAMEDKKEGMLREWCMACGNCVLHLTGGICPIARCAKSLLNGPCGGFYQGKCEVDGRTRD
CAWVLIFNKLKERNRLDLFTAIRLPKDYRDVKNPRELKREELVLPEAKEAIKILEEVEVK
RRPAYSQLMKELSEGRFVVTGELEPVKTTDLTEVIEGAKLLRDYVVAINITDNPTAFAYL
NALVPSYIIQEKAGVEAVYQMVTRDRNRLALTADLLAAGALGIKNILALAGDFTTVGDNP
QAKKVWDIDSTLLIYLISKMVDEGVDLAGNPIHNPPKFNIGAAANPNADPLEPELYKLLR
KQKAGVDFLQTQSMYDIEKIKHFLDECKSIGIRVPILIGITPFKSIKMMEWFVKNVPGVY
VPEEMQERLRKARDRGKEAFIEENIVVFGELCREIRKTTSAAGIHMMAVGMESLVPRILE
IAGIGKYRSS
>A0A7C4GXK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MVQAFSNLMKNILDGKFVYTGELEPHKSMDLSEVISWAKILKETGKIVAANVTDNPKSVG
SISSLVASYIIQRETGLEVIYQLRCSDRNRLALVSDLLGAAALGIRNVLALTGDHPRQGD
MPTAMPVYDLDGTQLVDLIHKMVYEGKDIDGNEIHGPRPQFNIGAAANPNFKPLEVEVLK
IERKAEVGAEFFQTQVIFDVNVALDFLDAVKHVKAAFLIGIFPPRSYAQAEFFAKHVPGV
QVPAEFLNKLKSISELPDKKERRRKIDEYNVEYFSDFIKEVKKKPSCKGIHIMAVGYPEV
VGPLIESVGGS
>A0A7J2IV81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MSGEKPVYSALMKNIRAGRFVYTGEAEPHKTTDISDIIEAFKALKGWVIAINVTDNPTAY
AYMSSLAASYLIQRGTGIEAIYQITCRDRNRLAITADLLGAYALGIRNVLALTGDHPSVG
DNPQAKPVFDLDSSTLVYLIRRMVDDGVDLAGNKIEHPPKFHVGIAANPNAEPIEPELLK
IERKVEIG
>A0A497MM76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MKKIAAGEFVYTGELEPHKTTDISETIEWARTLKATGKVTAANVTDNPSSTACISSLVAA
YIIQRETGLETIYQLRTADRNRLALVSDVLGAGALGLKNILALTGDHTMLGDNPQSKPVF
DLDGTQLIAMIKQMVYEGKDPAGNEIANPPKINVGAAAQPGADPLEMEILKMERKVEAGA
EFFQTQVVFDVEVALKFLDEASHLNVPILIGIFPPKNYGQAEYFSKYVPGVTVPDQFLAD
LKKLSEISDKAERKRKINEYNVEYFSNFIREIKKKPVCKGCHIMAVGYPEVIGPIVERVE
KGA
>A0A352T3C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MDNIRDYLKDNILITDGAFGTYYAGLYDTRELPEKDNINYKDRITAIHREYIEAGARLLR
TNTFASNTINLDTDIEGVRANIKAAVQNARQAALLSGKDVYIAADIGPIPNDNMFDRQIT
ENEYVQIVNTFAKLGVNIYVFETFSDISHIIEAIKAVPKDAFIIVQFAINQYGYSSSGLS
ARKLISLADEIDSIDAVGFNCGIGPAHMEQFVSRNRKYTKKIFTALPNAGYPQVISGRMV
FSDKNIEYYSQKVCDLVRAGADIVGGCCGTTPDYIKNISEMIRSSHISCNINIDTDGDFN
KTSVKNSAFYCGKEGKKLIAVELAPPFDSDADKLMDAAHYLKEKGVDVLTFPDSPSGRTR
ADSILIAAKVSRQTGMCVMPHLCCRDKNAIAIRSQLLGAHINGINNFLVITGDPIPQMIR
SSVKSVFNFDSVGLMNIIEDMNEDQFKYEPVVYGGAINQGRKRLDIEISRVKKKMEAGAA
FFMTQPVFSDEDIKRLSTIKKETGARILCGIMPLVSLKNATFMKNEMAGIDVTDEVLSRY
SEDMTKKEGEAAGVKLAVDMINKTKDIVDGYYFSFPFNRVYMLEDILSMSQI
>D0P2W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora infestans (strain T30-4)|TrEMBL
MGKIIESIRSAYATRTDDTSARPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGAEQWSPVEGGLSNAVDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIHWCKTRVPEKVLAALDAIKNDDAAVRRYGK
GQSR
>A0A7J3BEJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MTGPNSELMRELIEGRFVFTGEIEPSKTTSLQGVLEAAKKLKGHVVAANVTDNPTAYAYM
NALIPSYIIQREVGLEAVYQMTVRDRNRLALTSDLLGAGALGIRNILVLSGDHTAVGEYP
GAKPVYDLDSTNMVELIRRMVDRGVDLGENRVIDPPKFHIGIASNPNADPLEPEVFKIER
KVMLGAEFIQTQAVYDVEVAKGFLDAIAYLNRPVLIGVAPFKSISAMEWMMRLVPGIIVP
EEIQSRLRRARERGGKEEFYRESIEIFGQLAHDVRKTTKAKGIHLMTIGFEWIVPSIIER
SIGA
>A0A7W6CMT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sediminicola|TrEMBL
MNALFNAYSIEATTKDVATLGALDADGLRPAQVFVPWLPEEGDEARIAACAAVARAGFAP
VPHLSARRIASVEALDALLAALRPHTSSLFLIAGDLAAPIGPFADSLSVIRSGLIERHGF
AHVGLAGHPDGHPDVAPAILWAAMEDKIEALRQRGIEAQIVTQFSFDAGQVLRWLHELRA
RGITAPVRIGIPGPASVRTLLRFAARCGVAASAGVVGKYGLSLTRLLGNAGPDRFLAQLQ
DGLAAQDLGPVHLHVFPFGGFAQFAGWLDGARAPLARSA
>A0A832LY72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MIIARRKPLKEILKMLEDYKKILILACDGCVGIYDVGGLKQAETLKLELEIAWKAKGMKA
ANVEVATVLRQCDTEIVKDSVSNLIVPVDAILSLACGAGVQTLAYVFPNKPIYPANDTMF
IAMENKKEEVWNEWCAACGNCILHETGGICPIARCAKSLLNGPCGGFSEGKCEVGNWVND
CAWVKIFDRLKHLGRMNDFIKIRLPKDYRDIQNPRKLAREAAIAKEKSIIESIEVFREVG
KRPAYSKLMKELASGKFVITGEVEPVKTTELTEVLEAAKILKEHVVAINVTDNPTAFAYM
SGLIPSYFIQEKVGVEAVYQMVTRDKNRLALMADLLAAGALGIKNILALTGDSTTVGDNP
GAKKVWDLDSTLLVYMISRMVDEGVDLAGNPIINPPKFNIGVAANPSATPLEVEIYKLVR
KQNAGADFIQTQSMYDIEVIKQFLEECRAAGVKLPILVGVTPFKSIKMMEWLVKYVPGII
VPEEIQEKLRKAREKSKEAFIEENIEIFSNLCKEIKKTNVAGIHMMAVGFEWIVPKILER
AKLKS
>A0A3C0MMU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKYSNTAGLLEERLKSSRINADGAFGTYYAKIYDEGSLPEMANVSAPARVFAIHRAYIEA
GAQIIRTNTFASNTVSLGQDIDDVRNNIRCAVKIAREACEGMGVLVAADIGPIPGENMFD
KEYIENEYVDIVNTFKELGVDIFVFETFPELSFINKAIEAVGDKCFVITQFAINQFGYSS
SGYSARKLIDEAAKNQYIDACGFNCGVGPGHMKKLVQNLINRNNKYFAVLPNAGYPQVVS
GRMVFADNNAGYFAQIMKDMAEEGADIIGGCCGTTPEYIRQMTALTAEVSHSRDIKHDNE
EQGDRTFIDCAFYKGKEGRKLIAVELAPPLGVNDEKIMDAAFLMKKSGVDVLTFPDSPSG
RTRADSILMAEKVSRETGMCVMPHICCRDKNAIAMRSQLLGAHINNINNFLVITGDPIPS
MVRSSVKSVFNFDSVGLMNIISDMNQDQFADKPVIYGGAINQGRVNFKVELARVKKKMEA
GATFFMTQPVFSDEDISRLRQIKEETGARILCGIMPFVSLRNATFMKNEMTGINVTDEIL
ARYSADMTKEEGEETGIQIAKEIITKTSDFVDGYYFSFPFNRVHMLEKILNA
>T3DJS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridioides difficile CD160|TrEMBL
MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAANVTDFQSAVMRATSLA
TCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLLALTGDHTSVGDHPQAKGV
FDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTPEYSPIEVQLLKMQKKIKAGA
KFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSPGMAKFMTANVPGIFVPDEQIER
LRAVGKENWVSEGIKMAGELIKQLKEEDLCDGVHIMAIGAEENIPAILDAAGL
>A0A0Q8DRZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. Root627|TrEMBL
MPAVSFEFFPPKTDEQRAQLDRTVAALKAYQPDYVSVTFGAGGSTLSYTAETARHLHEQH
GLPAAPHLSCVGGNRAELAALLDDYRAAGYRRIVALRGDLPSGMATPGDFRYAAELVRFI
REHSGDHFHIEVAAYPETHPQADNALRDLQHFKAKVDAGADGAITQYFFNADAYFRFVDD
VQRLGVNVPIVPGIMPITNYSQLQRFSDMCGAEIPRWITQRMRAHGDDADAVRKLGTEVV
TTLCRRLLDGGAPGLHFYTLNRAKATEAVLKQLA
>X0S023|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. JCM 18901|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALST
RGTTEIAPHMSCIGDDKSEIAELLEYYKTLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
YIREHSGDHFHIEVASYPEMHPQARSFEFDIDNLVNKYQAGANASITQFFYNADSYLYLR
DKLEKRGIDTVAQPLVAGIMPITNSSNLLRFADSCGADIPRYVRKQLTDFGDDRKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLTA
>A0A2I2G502|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus steynii IBT 23096|TrEMBL
MHVKDKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDNALQAAYKAGCTNILALRGDPPREKET
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNSDVDLLIDHLKEKVDAGASF
VITQMFYDTDNFIEWVKKCRAKGVDVPIIPGIMPIQTYAAFIRRANWTKSRIPPDWLEIL
EPVKNDDAAVKDIGKGLVADMCRRLIASGINHLHFYTMNLAQAVQLVLDELDLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPTSIRDLAHIFVRYLEGKLERLPWSDTQLSTEANVIKDKLIE
LNNRGLLTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLVPPYLLEELIGRIEKNE
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHEATTPSRKLIQGVVDDWYLVNIVNNDFHNTFSLFELFDGLNVKDLDTEVSADNAAPK
QLSADAAAPEIAVKN
>M5EV05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium metallidurans STM 2683|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKNDEMEARLWDTVTRLEPLRPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVNAARHEVDAVVQEFADMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGIGEFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEVEAA
GSAAA
>A0A3D0GV22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKIVDIIESDKVTLSFEVFPPKTSGQYDEVSKAAMEIASLNPDYMSVTYGAGGSTKGYTF
KIASDIQKYFDVPTLAHLTCCLATKDSIKEALSQIKENDLHNILALRGDRPKGYEGDPFI
DYKYASDLIEDIVKTGDFCIGGACYPEGHVDSLNKSEDIDNLKKKVEAGCSFLTTQMFFD
NNIFYNFLYKVRDKGITVPVVPGIMPITRVNQVATAKKLSGCNVPERFTNMVDRFADDNE
ALETAGIIYATEQIVDLIANGIKHIHVYSMNKPHIARGIKENLRGIIGK
>A0A1I7EXW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas eutropha|TrEMBL
MQSQKKFTPTFSFEFFPPQTPEGMEKLRATRLQLAQFNPKFFSVTFGAGGSTRERTLETV
LEIQAEGYPVAPHLSCIGSTRDNIRSILEKYYSHDIRHIIALRGDLPSGMAQAGEFRYAN
ELVAFIREEFGDTFWIEVAAYPEYHPQARSALEDFTNFRRKVEAGANAAITQFFYNVDAY
LHFVEMCEAANISVPIVPGIMPISKFSQLARFSDGCGAEIPRWIRRKLESFGDDIPSIQA
FGLDVVTALCARLLEAGAPGLHFYTLNSAVLPTKIWQRLGL
>A0A3M4VHS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. syringae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEAITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1V5DD76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophus sp. PtaU1.Bin005|TrEMBL
METLFEASLKDPAVMTVTWELVPGRGAREKAQDSVLLEAEKAARGGKIHAVSLTDNPGGQ
PALMADALAVEIKALGIEPLVHFTCKDKNRSQIESQLYALERWGIRNLIVMSGDYPVSGF
QGRPQPVFDLDPTHVLELIRELNGGLKFPLPKGTGELQPGHFFAGAAVSPFKHTEAELLC
QYYKLKKKIDSGASFIVTQLGYDVRKYHELLLYMKRREIDVPVLGNIFLLSYPVARLMME
NRLPGCVVPDDLLAQLDRERSLPDKGLEARLSRGAKMYALLKGLGFSGVHVGGHLVTCEQ
VEAVIEKGEELSASWESLIPEFQYSTPGAFYYFRKDPYGRLNELIPESRQGSRSSLSERR
LYGISRFFHNLIFEPGTKGFALMRSLAAKLKGSRLEGLLHKLEHLLKTLLYDCRDCGDCA
LVDVAFLCPMSQCPKQQRNGPCGGSFQGWCEVYPGRRRCVYVRAYDRLRGSQQESRLEEI
PVPPCNWDLNSSSGWLNFFLGKDHTAKRLGIEEPSDQSR
>A0A6B8JT66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spiribacter sp. 2438|TrEMBL
MATCINPAKENRTNGFTAGPARYELIPIRGLLDAAKALPTGSTVAVTCSPRHGLERTLDA
AESLMGIGLRAVPHIAARLLRNEAEVQRTIKRIHRAGMDEIYVIAGDAETPVGDFCSALP
VLTIVSEMEERPTRVGIAGYPEGHALISDAALDEALWAKAAHADYVVTQMCFDANRISAW
VRRVATPESGLTAWIGLPGVLEMRRLLAVSLKIGIGQSLRALRRQQGLSGQLLQGHYTPD
DLLRSLLPLVDDPAMRVNGFHLNTFNNVPPLMDWREAFEAASVSSRQ
>A0A418WK81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas cavernae|TrEMBL
MTFTLSQLEEARRALDAPLFADLAGDAQVSFEFFPPRTEKMEQTLWEAIQALVPLGPRFV
SVTYGAGGSTRERTHATVARIQSETPIPAAAHLTCVEASKADIREIAEAYWEAGVRHIVA
LRGDPPVMGSKFAPHPEGFAGAADLVAGLREIAPFEISVAAYPETHPEAQSGQSDLDNLK
RKLDAGANRAISQFFFSPDCFFRFRDRAAAAGIDAEIVPGILPVSNVAQTRKFAAMCGAA
IPPWMDRLFEGLDDMPAARQLVAATISAELCRKLYAGGVRHFHFYTLNRAELSYAICHLL
GLRPKADAQEKAA
>A0A829M7L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus epidermidis CIM40|TrEMBL
MSHLLNQLKSNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKSFGLEHKVKEIHQAAVQIAKRAANEDTIILGTVGGFRGVRQEDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELTRIVTATRQKYDIPIIAQLTASNTNYLVDG
TEINEALKYVVECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDIAQELINEGVRLIGGCCGTTPEHIRYIKSAVKHLKPVKDKKVIPINKAS
SQKETRVLKQNLTSKVKNGPTVIVELDTPKHLDTDTFFDNVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQRYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGINTDGDALKKHTNFNIAGAFDPNVRKLDGAIKR
LEKKVASGMSYFITQPVYSKEKIIQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSDDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A6B8VXC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium occultum|TrEMBL
MSSHADMLNANAHQRRHSMLSGEKHRFTRTTRVSASAPLDDDIFSGIDSEKSTPALDPTD
LLGWAPGARHRTSLSFEVMPPRHDTDETKIENLLATLESYGPDYLAVTSSLRSGWLEGTS
NFIAQIDQNTRMRPLAHLTCTAGPTEELIGWINRLVDSGVRGFLALRGDYPEGQTGPDLG
HLPYATDLIRLIRDVEKRQAARFGAGRLAVGVAAYPSGHAESQSHDEDIDVLLAKQRCGA
DFAITQLFFDAEDFIRFRERARLAGVSIPLIPGIIPITSVQRLRRMGGLSGLQVPERLIR
RLEAADTPEGQYEIGMQATADLARTLLSADTESLHLYTFNRPDVTVELLDRIGIAPRTKR
RQRS
>A0A7C3ZCY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MPNKLKESLENNVFVYTSELSPERGADLSKMKGIYEILKDRVSAFNITDNQGANMKMSSL
AGSIYIKQAGGEPIFQQTCRDRNRMALESDLLGASAFGVKNILALTGDYISFGDHKHAKA
VYDIDSVNLIEIVKGLNAGADMNGNKLNGPTDFYIGAAVNPESVPLEPQLVKFEKKIKAG
CDFFQTQAVFNTGKFAEFYDFYKNFKNIKIIAGIYILKSSKTARYMNKFIPGIYITEQII
NELENASDPLKKGIEIAVRTARELKPLVHGIHIMAYGIESQIPIFLNELEAL
>A0A7C6Y487|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MATGDLRKIVESGNFVVTSELGPPKSAAVEKIRQLAELMKNHVDAFNLTDNQTAIVRASS
IACGKILADMGLDPIVQITCRDRNRIAIQSDVLGAVALGIKNILCLQGDHQSFGNEPGSK
GVFDLDSTQLIRALKNMRDEGVFIGGDKLEAPLGDIFIGAVANPFADPFEYRIHRLAKKI
AAGADFIQTQAVFDLDRFERWMEGVRELGLHKKVPILAGIIPLKSLGAARYLKNNVSGII
VPDALIERMQHAGNKKEEGLRICVETIKRVRKIEGVAGVHIMAIAWEEVVPEIVEGAGLM
PRPRPV
>N6Z2L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera phenylacetica B4P|TrEMBL
MYRVRLWSVRHARRLRSLYELFSRLAPLMRPVARVLGVDRTAAVLRPLERHAKGFLFDCR
MCGQCVLSATGMACPMNCAKEMRNGPCGGVRPDGHCEVRPEMRCAWVEATAGTKRIAPDH
KAHPTPLLPAVDQRRRGQSTWIQVIHGHKEPAFQPPVAHDSTREAEESALEAACRSGRFV
VTVEIAPPDSADPSVLLARAERFRGLVDAMNVTDGAGGNCHMSSVAASAILAHAGFNPVY
QVACRDRNRIAIQGDILGAAALGVKNILCLTGDDVSQGDHPQAKPVFDLDAVSLLHVARG
MVDRGEFASGRKLESAPRLFIGATCNPFVPPFVDRIANLEKKVVAGACFIQTQFCFDLPL
LEAFMDGVRARGLHRRAHILVGVGTLSSAKALRWMGAHVPGVHVPEAVLQRIGSATDQKA
EAARVCLETIEAIRGIEGVAGIHLMGHRNEEALADIIRRAGLPARTGGGAAGGGFPGLPG
PRG
>A0A8B8F026|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crassostrea virginica|TrEMBL
MPELLNGKTCNRNSQHREAPYSPVQESEYGEYRSLTERMNRRIQSGDPWYSLEFFPPRTA
NGAVNLVSRIERMSEGGPMFCDITWHPAGDPGNTEKPTSSTCMAATMLNYCGVETMLHIT
CSNQDEDEIKRNLKKSKDIGLKNLLALRGDPPDGGLTWTKQEEGLNYATDLVKLIRREHG
DHFTICVAGYPTGHPESTSYGDDLRHLKEKXDAGADFIITQLFFKPETFFQFLRDCREIG
ITCPIIPGVLPIQAYQSLRHIVKLSRLEVPKEILDAIEPIKDNDEAIRNFGVEQCFQMCR
ELLKHEDVHGVHFYTLNREVATIEILRRLGMWVEEPCKPLPWKQTANYVRCKEDVRPIFW
RSRPKSYIHRTSNWDEFPNGRWGNSSAASFGDLSDYYLFYLKHKPQKEELLKMWGEELNS
EQDVWDVFHCYISGCPNKMGVKVCSMPWNDDELSAETNLITEQLEAINKRGVLTINSQPN
VNGAPSSDIKVGWGSPNGYIYQKAYLEFFTTKENGIALKKILKXYPLVNYHIVNKNGEED
YTNCDLTTPIAVTWGVFPGKEIIQPTVVDPIAFKTWKDEAFELWKHPWGNLYPEGSQSRK
ILDHIFDSYYLVNLVDNDFPKDSCLWRIVEQMLEAGRQTSSVEQMDVNGQ
>A0A357D504|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MRIKDLYQQKPVISLEVFPPKPEAPLDGVLDTIEALSDLRPDFISVTYGAAGGSKAHTVQ
IADTIKNKYGIEALAHLTCINSSKEEVDGILEELENSNIENIMALRGDRPADDSVLSPAQ
GDFAYASDLIVHLKTTGDFCIGAACYPEVHTEAENALADLGNLKRKVNAGVDFLITQLFL
DNRFFYAFREKLALMELKVPVSAGIMPVINKKQIERITSLCGASIPPKFRRILDKYENDP
EALKEAGIAYATEQIIDLLSNDVDGIHLYTMNKPEVARGIIGQIGRIREFLRDGV
>A0A6I5CFN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID625|TrEMBL
MALGTASTRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPRGLRYAAELVELIKTSGDFCVGVAAFPAMHPRSVDRDTDVRHFVD
KCRAGADYAVTQMFFDPEDYLRLRDRVAAAGCETPIIPEIMPIASVKTLARIPSLTNAVF
PGALKERILAARDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
PHRSPRA
>A0A7C6ZE94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MGLREALASGKVVVTAEVAPPKGTDLTAFRESLPYLRGRVDAVNVTDFQSAVVRASSLTL
CRLLLEEGLDPVLQITGRDRNRIAIQGELLGAAILGIRNVLAITGDHTEIGDHPGAKPVF
DLDAVTILQAAQRLNQGRDLAGNPLRGATDFTLGATVTPCYEPLELQVLKMESKIAAGAT
FFQTQAVYEVEAMRRFREATAHLGDVKVLVGIIPLKSAGMARFMNKNVPGIRVPEELLER
MAAAPDPVAAGVKAAGELMAALLAEGLCDGFHLMTLGREDLVPEILAAAGLA
>A0A7C5RHF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
YINLPQIIDESRENTRTFKYTPKVENYIFAKELTQYCKTNFNLDIHPIINVVVPIIPKAK
FIDYFKKIYDLGFDTFLLIGKDKSNIQYPGYEVTEASHILKDYFNNIKIGGITIFHRENE
IKRIINKINHGIEFLVSQIIYNTSELEKIIENLHLYNIKTKIFVSIAPVTNTKEIEFLKW
LGVNLNNINFNHDIQNSSIEMIKNIILNISEINLSNLKLNKDITLGFNVEHITYNNLELS
EKIIKIIKLKLENLKLLSSKISNLK
>A0A8C0A873|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos mutus grunniens|TrEMBL
MDRPKPKVFPVGHCCPSLGMRASEAGSGRLSVPPSISRNSAMVNEPRGNGSPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKVRGPRAGLPCPPTEPCAGRVARSWVGGWRLHPQGWQ
QPDSDSRCFTSRPGRGVVLAMGYAEFLEYILLGSSRGPWGAEHGAPT
>A0A7C1PR50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MTPVSNLQSVLEQGYFAVTAEIGPPKGASGEEILRRAALLKDYTDAQNVTDNQSAVVHLC
SLAAAVHVLRAGGEPVFQLTTRDRNRLALQSDLLGAASLGIRNVLCLTGDHQKFGNHPQA
RGVFDLDSVQLVALARRLCAGYFLCGDEVKPPPRFFVGAVENPCADPLPLRVLRLGKKIA
AGACFIQTQVVYDVDRFARFMAAVREQGWHKKVYILAGITPPKSAGTLRYIGKVPGIVVP
EAVIRRMERAADPAREGKRIAVELIQQLRAIEGVHGVHIMAIRWEEAVPEIVSEARLFPR
PKTQANQLSSGREEN
>A0A5B9GEW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter oryzoeni|TrEMBL
MSLSRLSVELIPRSAEALATDVATVKATFSVADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQPGLEEILVVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMLGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLDANIQFAQTVLKELAQEKGKAYLMPVRIKLEQY
LPHLLDAVA
>A0A523XPY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division TA06 bacterium|TrEMBL
MAKPFREALKTKDFVVTAEAGPGKGSNVAKMVEHIELLKDRVDGLNVTDNQSAVMRYPSL
GTCLLIKEHGGEPVLQITCRDRNRLAIQADLLFAYSRGVDNVLCLTGDSVDVGDHKEAMP
VFDLDSVQLIHLVHALNSGRDMVGNELDGGVDFCIGASGTPSADPIEPQLIKFGKKLGAG
IDFIQTQAIYDLDEFKRFVEYARKTDAKAKILAGIVLLVGAKMATYMNENVPGIYVPQYL
IDELAQAPKGKGIATGIEIAGRLIRQIKEEKICDGVHIMAIGREERVPEILEAAGL
>A0A355IA97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MARLLNRLTQGQFVVTVEIDPPRGPDAAKTLEKLRGFADRVDAVNVADCPMANVRMSPIT
LAHLIQRDAGVEAIFHLTCRDRNTIGLQAELLGAAGLGVRNILALRGDEPTRGDHPSATG
VFEIGSSRLIKLASTLNAGSTIGGSGLDCGTDFTIGCVANPNAEDLEAEVDCLEAKIAAG
AHFAQTQPVFDLRILEHWLMKAAGRVRIPILYGVMPLRNYEFAVHLNNDVPGITVPEWAV
ERMRVRGPQAGMEMVREFISSASAASEISGIHIFPMNNAARILKVVDIIDELGLRCQRKA
KPIRIGTRD
>A0A022RA58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythranthe guttata|TrEMBL
MKVIEKIQEAARANDDRVVFSFEFFPPKTEDGVDNLFERMERMVVHNPTFCDITWGAGGS
TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALASIKSNGIQNVLALRGDPPHGQ
DKFVQVEGGLACALDLVKHIRSEYGDYFGITVAGYPEGHPDVIQEGGASAEAYQSDLAYL
KKKVDAGADVIVTQLFYDTDIFLKFVDDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPAEIMAALEPIKDNEEAVRAYGIHQGTEMCKKIIASGIKTVHLYTLNMDKSALAILMN
LGLIEESKISRSLPWRRPANYFRVKEDVRPIFWANRPKSYISRTIGWDQFPHGRWGDSRN
ASYGALTDYQFMKPRSRDKKLNEEWAVPLKNVEDIYEKFVKFCLGKLKSSPWSDLDGLQP
ETKVINEQLGSINLKGFLTINSQPAVNGARSDSPSVGWGGPGGYVYQKAYLEFFCSKDSL
NALVNNCKLFPSLTYMAVNKEGNWISNANKTDVNAVTWGVFPAKEIVQPTVVDPASFMIW
KDEAFAIWSPGWAKRYPEADPSKKLLEEVESSYYLVSLVDNDYVGGDLFAVFKNI
>A0A521ZBN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MSRTFSFEFFPPKTPEGQEKLRITRDVLAQLKPKFFSVTFGAGGSTRDRTLETVLEIQQS
GFDAAPHLSCVGSSPDNIRAILQQYKDNGIHHLVALRGDLPSGMGSEIGSFRYANELVEF
IRKETGDWFNIEIAAYPEYHPQAKSPADDLDNFVRKAKAGANSAITQYFYNADAYFRFVA
AAQARGVTIPIVPGIMPITNTTQLLRFSDACGAEVPRWIRLKLASFGDDMASIRAFGLDV
VTGLCQHLLEQGAPGLHFYTLNQAVATRTIWERLGL
>A0A450ZW37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. TC|TrEMBL
MTMHLSGSIPRVFSFEFFPPKTLKGRNTLRATWRRLSELDPDFFSVTFGAGGSTQAGTME
TVLEIQRDSSIDAAPHLSCIGSTRVKIRNILEHYLSNGIGRIVALRGDFPPDMVELGEFR
HANELVAFIRAEVGDDPRIEVAAYPEFHPTALSASADLENFKRKVDAGANSAITQYFFNK
DAYLRFVDSCQRIGVHIPIVPGIMPITNYVSLAGFSERCGAEIPRWLNWRLQEFGDDMKS
LREFGVDVVTELCQGLLDAGAPGLHFYVLNRAEPVMTIWKNLGLSETRGSR
>A0A2V2EVQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MKIFEVLQKKRTLSFEVFPPKRADVGTKGVFATIDALKELSPDYISVTYGASGSNSRNAA
EIAGYIKKSGIEPLAHLTGGPSSPQDIDRTAQEFLSLGVENVLALRGDKPVDYEAEYCKY
FPHATDLMEYLKKYPFSLAGACYPEGHPECDTLYKDLEAMKRKEECGAKFFVTQLFYDNS
YYYRLVNEARRIGITSPIIPGIMPLLKVQNIKRVKEMCGSAVPLEFRNMIEVYSDRPAVM
EEIGLNYAVYQIIDLIAKGAPGIHLYIMNNAGAAHAIYSRLEKVFRELF
>A0A5P1UW19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. C16S1|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIKRFVEKVQAGANAGITQFFFNPDAYFYFI
ERLEKAGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLSAYGDDSASIKAFGHE
VILKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A379N6V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas gilardii subsp. rosea|TrEMBL
MNHVATPGAGASGAGPGLEPGANPLGRWLTGPRFGALPAPAALPAPALSFEFFPPRTEAL
ENQLWACIRRLEPLGPRFVSVTYGAGGTTQARTHATVSRIVRETALTPAAHLTCVGASCG
EVDEVARQYWDAGVRHIVALRGDPPAGASDYVPHPQGYAYAADLVEGLRRIAPFEISVAA
YPETHPSASSAGADLDNLKRKIDAGANRAITQYFFDTETFLRFIDRALAAGISVPIVPGI
MPVSNFNQMRNFSARIGASVPDWMAALFEGLDDDIETRRMVAAVVAAEQVRLLQANGVDE
FHFYTLNRPDLTYAIAHILGVRPARPTEPASESGPAEEVKAEAAERQAGA
>A0A1G2WSE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium GWA2_39_15|TrEMBL
MKSGSNLERLLRGRHFVVTAELGPPRGADRSVIEKKAAILKGYGDAFNITDCQTAVVRMS
SIAAGRIVLDAGLEPIIQMTCRDRNRIAIQSDLLGAAALGAKNLLCLTGDHQKFGDHPMA
KGVFDIDSIQLIQIVKILRDEKKFQSGQELKTSEPRFFIGAAENPFADPFKFRAIRLAKK
ITAGADFIQTQIIYNVKKFNDWMKMVTDMGLHEKAFILAGVAPLKSAGMAKHMKHNVPGM
DVPDEVMNRMNAASAVKKGKEEGIKICLEVIEQVRAIEGVAGVHIMAVEWEDAVPEIVKQ
AKLHPRPAI
>A0A1J5IDY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomicrospira sp. CG2_30_44_34|TrEMBL
MYSQQKYTQHLSLEFFPPRTDAGIEKLKTVIESLEIIQPQYMSVTYGAGGTTQARTIETV
DYIQTQTQFDAAPHLTCIGATADSVRELLNTYSQMGIQRIVALRGDLPSGMMDPGEFKYA
SDLITFIRQERGDQFHLEVAAYPETHPQARNCDIGIKWFKHKIAQGADSAITQYFYNVDS
YLYFIDNCERSGIDLPIVPGIMPITNYENLIRFSEGCGAEVPRWLKCRLESYGDDTESLK
AFGQEVVTEMCQRLLDAGAPGLHFYSMNQAEPTTGIVQALTFKSPLE
>A0A5J4FYL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Patiriisocius marinistellae|TrEMBL
MKVTEHIKEANGKTQFSFEILPPLKGQNIQQIFDNIDPLMEFKPPFIDVTYHREEYVYQE
QENGLLKKKIVRKRPGTVGICAAIQNRYQVDAIPHILCGGFTKEDTENFLIDLGFLGIDN
VMALRGDAVRNETYFTPEGEGHTYASELVSQIQALNNGEYLDAEIQNQSKTDFCIGVAGY
PEKHIEAPSLDSDIHFIKKKIASGATYIVTQLFYDNKKYFKFVDKCRKEGITVPIIPGLK
PIATKKQLNLIPHRFACELPDDLIMEIVKCNDNKAVRQVGVEWSIAQSKELIEAGVPVLH
YYSMGKSDNIRSIAGELF
>A0A1G7LZH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. DSM 44268|TrEMBL
MTVTQTVRELLASERPTWSFEFFPPKTPEGEQQLWSALRELERLQPSFVSVTYGAGGSTR
EGTVSVTERIATETTMTPLAHLTAVDHSIAELRHVVSRLAAAGVRNIIALRGDPPGADPQ
ADWVAHPEGLSYAAELVELIKSMGDFSVGVAAFPERHPRSPDFDSDVDMFVAKCRAGADF
AITQMFFRADDYLRMRDRVTDRGCDVPIIAGVMPVTNARQIKRIVQLSGQAFPAELAERF
EALDGDRPEDKAAVRAYGVEVATDLCRTLLDEGVPGIHFITMNRSTATREVHANLVGAPS
VTTAG
>A0A1B0VKU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium islandicum|TrEMBL
MNEINREDFFENRFILETLPPRGTNPDKYIAFCKEAVDYGAQVIAVTDLPMGSARVSPIA
PAHMLSELGFNVLMHFSRTTRNAIRIEGDLIAAHMLGIKNLLILSGDDPRVGTYPFSSSI
EDFSIYDVFKLTKLLNEKGEDLAGLKIYGSFSFNPGGVFSPFEKDLNQTLERMELKIQNG
CSFFVSQPIFNADTIIKFLEKSEAEEIFKKTKIYIALMVFESFQQLEHFSKVPGVYVPKE
YFRQKDDSHLEEYSKHQCVSIIEKLAPYVHGFYLTSTTRKMETIKVVSDAVMSQY
>A0A5C7PL10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MNKTPFSIEFFPPQTAEGADKLRAVRQKLARLKPEFFSVTFGAGGTTQERTFEAVFEIQQ
EG
>A0A2A4M3E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MTDRYFSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSTRDSIRQILQTYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQARSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRAMGVEVPIVPGIMPITNHSQLMRFSEMCGAEVPRWVAKRLESFGDDKEAIRAFGLDV
VTDLCTRLLDAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A3C1YGR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MSGLKAASNLQKMLDSGHFAVSGELGPPKSADISTLKHHAHDMRNHVDAYNITDNQTAIV
RTSSIGVAATLMQMGLEPTVQMTVRDRNRIALQSDLLGAVSFGVRNFLCLQGDHAKFGNE
PGSKNVNDLDSMQWIQAVKNMRDEGVFIGGEKLEHPLPDLFIGAVANPFADPFEYRPYRL
AKKIAAGTQFVQTQCIFDLDRFERWMVKVRELGLHKKVHIVGGVTPIKSIGAARYMQNNV
SGMIVPEELITRIKGAQDKKQEGIRIAVETIQRLREIEGVAGVHVMAIAWEEVVPEIVER
AGLYPRPSLA
>A0A839YZH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limimaricola variabilis|TrEMBL
MTRPAVSFEFFPPKNIEGSFRLWDTVQALAPMGPEFVSVTYGAGGTTRKLTHEAVDAIHK
KAGLRVAAHLTCVEATKAETLDIVQGYAKAGVEEIVALRGDPPKGSGGFRPHPEGFSGSV
ELIETLAAMDRFRIRVGAYPERHPDAAHELADVEHLKRKFDAGAHSAITQFFFEADTFFR
FRDACEKAGITGPIIPGILPIENWKGARKFAAMCGTSIPQVVADGFDHAKDQAEADLLAT
ALATELCDKLIAGGAEHLHFYTLNKPDLTRDVCHALGITPKATLSEVA
>A0A7L3RWM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cepphus grylle|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVAGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7X7PDY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Cloacimonetes bacterium|TrEMBL
MTIHDLLTDRRPAVFDGAMGTMLYSRGVYINRCYDELSLREPDMIREVHREYLRAGAEIL
ETNSFGANRLKLAEYGLEAQVEAINASAARIAKEVAGPNALVAGAIGPLGIRIEPYGPTS
LDEARALFREQAAALLEGGADFILLETFADLDEVHQALLGARDAGASAVIAQMTVKEDGT
TVYGTAADVLAAKLDEWGADAIGLNCSVGPAVILSALETMARATDRPLSAQPNAGLPREI
AGRKMYMASPEYMAKHAQRMIRAGVQFVGGCCGTTPEHIRRIADAVHSVAPRRTLVQVQA
HPETAAPVAVTPLAERSNWGRKIATGELVATVEIVPPRGITPAKMLAGVRLLKKAGVDAV
NVPDGPRAQMRMGVLPTATLVEQIVGIETVVHYCCRDRNLLGMLSDLLGAHALGLRNLLL
ITGDPPKMGPYPDATAVFDIDSIGLTNLVNRLNHGHDPGGNSIGEPTSFTIGVGVNPGAP
DFENELSRFYWKVDAGAEYAITQPVFDAAQLLRFIDEIERRNLRIPIVAGIWPLVSARNA
EFLANEVPGVTVPPSVVERMQRASARSREHALAEGIAIAREMFDEVKGAVQGLQVSAPFG
KVEFALQVFDGINGIDCSVSLDDVVEDSEFGFVPPAQAERDAVAPGTAGG
>A0A1I6IF06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halogeometricum limi|TrEMBL
MSLGTRTVSHPDGVETLLTGARFELMPFESFDEEITHLPDGATIAITTSPQLGIERTVER
TETAAELGYDVVPHIAARYVEDRDQLRDIARRLRDAGVTDIFVPGGDKEEPVGEFESAYD
LLSALDDMEYYFEEVGITGYPEGHDFIDDETLMEAMQRKEPYATYIVTQLCYDPETVVEW
IEDIRAQGVDLPVEVGIPGVMKYQRLLQISKKVGVGDSVKFLKKTTGILGFVKQLVGSRG
TYKPDELIDGLAPYVGDDEYKIRGIHIYTFNQTPDTESWRYGRLED
>A0A3D0T1V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp|TrEMBL
PLKPAYMSVTYGANSGERDRTHDVVKRIQQQTGVTAAPHLTCVDASAEELKQIARDYWDS
GIRRIVALRGDLPKGVEKTDMYASDLVALLKDVHDFDISVAAYPEKHPEAPNAQFDLLNL
KRKAEAGASEAITQFFFDTGVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNV
HVPGWLHKLYEGLDADDQTTRNLLGANIAMEQVKVLAKEGVKHFHFYTLNRSELSYAICH
MLGVKPQNAG
>A0A1F9MMA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca sp. RBG_16_58_9|TrEMBL
MKLTELFAKEKFVVTSEVGPVKGCCRPGEPGDQPAFVQEAVSIRDYVHAVNVTDNQSARM
RLGSLAASVLLKRHGIEPIYQLTCRDRNRLALQSDLLSACSLGLDNVLCLTGDHLRMGDH
PSAKPVFDLDSVQLLEIARGLNQGRDMTGHQLTQPTDLCLGAVVNPNFQPLDLQLLKMEN
KIAQGAQFFQTQTVYDPKLFETFIRRVEGFGVPIQYGLVVIKSPQMARYMNEHISGVTVP
LDLIDEMAGVPPEGYKDKAREITARLIRELAPMVQGIHFMPLGWSDLIPQVMAKIKGFCR
>A0A1G0QLW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium GWC2_36_12|TrEMBL
MKVIEHLAKAKEPLISFELIPPKRGGDFISLLSVIEEVSKYNPPFIDITSHPAEVVYEET
SKGIKKIIKRKRPGTLGICALIQNKYNIDAVPHVLTNGFTREETEDFLIELNYLGIENVL
AIRGDDLGYQKPVPEGRSKNIYAADLVKQIVNMNNGKYLEESLLDAKPTNFCIGVSGYPE
KHFEAPNLKTDVKFVKQKVDAGAEYVVTQMFYDNKVFFDFVDLCRKEGINVPIIPGLKIL
TTKAHLVTIPKNFYVNLPQDLVEEVNAAKPEQVLDIGVEWAVKQVNELLDKNIPSVHFYI
MQNSKPVKKLMERLKQFKKIA
>A0A435HZN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.13.2.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A521V2F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium|TrEMBL
MAVSVPISFEFYPPKTDEQRSLLDRSAAKLRTQSPEYVSCTFGAGGSTLSYTPETIQRLR
ERHALDAAPHVSCMGGSREEIRKLLKLYRAMGCKRLVALRGDLPSGMARMGDLRHATDLV
AFIRAEHGDWFHVEVGCYPECHPQAEDALADLRHFKAKVDAGADGAITQYFYNADAYFRF
VDDVRKLGVQVPIVPGIMPISNFSQLRRFSEACGAEIPRWISKRMQAYGDDADSIRGFAA
EFVAAMCMRLVDGGAPALHFYTLNLSKPTLNVLRNLR
>A0A1I4YU25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium ummariense|TrEMBL
MKVTEHIQNADGKALFSFEILPPLKGQNIQCIFDTIDPLMEFNPPFIDVTYHREEYTYKD
VGNGLLEKKVVKKRPGTVGICAAIQNKYKVDAVPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKAEKNGHRYASELVTQISELNNGIYLDDELENSHTTNFCIGVGAY
PEKHMEAPNFDTDLQFLKQKIDKGADYIVTQMFFDNAKFFDFVDKCRKSGIEVPIIPGLK
PLTTKGQLNMIPHRFKVDLPDALVIEILKAKDNEAVKQIGIEWCIQQSKEIIAAEIPIVH
YYSMGKSDTVKRVAKEVF
>A0A429WDQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. DXTD-1|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYACKPEFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFLYASDLVAFI
REETGCDFHIEVACYPEVHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
ARKLGLNIPIVPGIMPIISSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
ADLCARLRDGGAQALHFYTMNQSAPTLAVLERLD
>J4GI53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibroporia radiculosa|TrEMBL
MKVSQKIALAEKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQKLIGMETCMHLTCTNMPREKVDVALKEAKEHGCRNVLALRGDPPMGKDE
WEAVEGGFVHGIDLVKHIRSQYGDYFDIVIPGFPQHVLLPPEEFALELQYLKEKIDAGSN
LIFTQMFYDVDIFIKWVHAVRAAGITIPIVPGIAPIQTWNGFQKATSLAKTKIPQLFLDA
LEPHKNNDEKVREIGTKLVADVCRYLLDAQIGIKGLHFYTMNLEKATRMLLEELNLVPRI
QTVKPLPWRQSLTPNRRAETIRPIFWANRTRSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQSKEEALQLWDSPTSAADIGRLFSKFCLGQLRALPWSDQAPSSETTVIATQLA
KLNDMGFLTINSQPAVDGARSDDRVHGWGPTNGYVYQKAYLEFFVSPGLLDALLPHIERD
VNITYYVINKRGDLRTNTHSEGPNAVTWGVFPNKEIVQPTIVEAISFMAWKDEAYELGRQ
WSKYYEPESQTRKLIDDIMETYYLVNVVHNDYKKPEAIFEPFFKAGAEFTALQIGQSSML
RDN
>A0A6A6X556|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melanomma pulvis-pyrius CBS 109.77|TrEMBL
MHISQKLAQARAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHSFGPQFVDLTWGAGGRLS
QLTCEMVKVAQSVYGLETCMHLTCTDMEKTKLDEALKDAHQSGCTNILALRGDPPREKEK
WEATAGGFRYAKDLVKYIRDRYGNHFDIGVAGYSEGCEDNEDVDQLIDHLKEKVDAGATF
IVTQMFYDTDIFLDWVKRVRAKGIDIPIIPGIMPIHTHAAFIRRATWTKCNIPTHWTEAL
EPIKNDDVEVREVGKGLVAEMCRKLIDAGILHLHFYTMNLAQATRMVLEELDLLPDLDSP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDARSPAFGELDS
YGVGLKGTNEQNIKLWGTPKTIKDISDLFVRYMGGKLDSLPWSEAPISKEADSLQKDLLD
LNKRGFLTINSQPAVNGAKSTDPVFGWGPRNGYVYQKAYLEVLVSPEFIAELITRIDRDA
DLTYYAVNKNGDLKTNAPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQDW
ANCHSSVSPARYVIEDIMDTWHLVNIVHNDFHVTHGIFPLFDGLQVQDMEKPLHDTGVAN
GDLVNANSPGGEKSILANAADAAKSATLAVANGLNGLALSN
>A0A7G8BU57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edaphobacter sp. 4G125|TrEMBL
MSQSVERGSREPGVKRLFTGSPVLCDGAMGTMLYSRGVFINRCYDELNLSQPDLVREIHT
EYLQAGAEVIETNTFGANAYRLEHFGLRDKVREINLAGVRLSREAVNQIRDKQATEAFVA
GAIGPLGVRLEPLGKIGLEEARAAFTEQIEALLEGGPGVGADLLSIETMTSLTEAEQAVA
AARAIAPEIPVIVMVTVDEDGNCLDGTSAEAAARRLTATGADAIGCNCSAGPATVLSVIE
RMRPLTTLPLAAMPNAGIPRAVEGRTIYLTSPEYMASFTRKLIKAGVTLIGGCCGTTPSY
TRAMRSALRALDAMETGAQVMERGPETPAAPKVAPPPLEHRSKIGSMVARGEFVSMVEIV
PPKGIDCSKEIHGAEQLHKLGVNAINVPDSPRASARMSAQSLCVQIQQHVGIETILHYTC
RDRNVLSIQSDLLGASSIGLKNILCLTGDPPKLGNYPDATAVFDVDAIGLVNIVRNLNCG
LDIGKNSIGESTGFTISVAANPGVPDLEQEVRRFAYKVEAGAEFAITQPVFDLRVLEEFL
RRIESFRIPVIAGIWPLTSLRNAEFMKNDLRVSMPDEIMARMANAGSPEAARAEGVKIAQ
EMLAEARPMVQGVQVSAPFGKYMAAAQVLGLVESGE
>A0A7W5V8N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea dietziae|TrEMBL
MTFQLVCEIEPPTKPDLTHVRHQIGTLGKLAHSFLIPDNHIGRATVSSVAVAHEVQSMGG
RSIACLNSRDRNLLGLRRDLLTAAAYGVDQFLFVYGDKPTVGNRTSDLTVRSMIEEARAF
SPSFRVGAAAGLRPLPAWKRAADFLFVQVSFSLDALLRWREQNQVDVPVYAGVMVLASRQ
HAQRLAAAIPDIDIPSELVERLGEDRMAGVEAACEQVLRLRDSGAFDGVHLIPVARYRDV
ESRLHDTL
>A0A849L2X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halovulum dunhuangense|TrEMBL
MTSTRTKGTPPKTLSFEFFPPQSPEAEAQLWRSVERLAPLSPSFVSVTYGAGGTTRERTK
VAIRTIQERAHLSVAGHLTCVGASRAETMEVAHAYRAMGVTRIVALRGDPPKGETKFVPH
PEGFTHAAELVEALAADGFDVTVGAYPETHPEAASPEADIDNLKRKLDAGADRAITQFFF
EADCFLRFRDRCVAAGIDAPIIPGILPIENFQRMSRFASACGTSVPDWMERGFADAAGDD
AAETTLATTIATDLCGRMLEEGVDHLHFYTLNKPDLTFNIARALGFEPVTPNLAAGNGVA
>D4IP78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes shahii WAL 8301|TrEMBL
MNVVEIINEAIASGRTRFAFELLPPLKGDGMQKIFAAVEPLMALDPAYVNITFHREGIKE
TEREDGSVEWHVVRRRPGTVGISAAIQNRYGVEVVPHLICGGLSKYDIEDTLIDMDFLGL
HNVLALRGDKSQNEKRFMPHPQGHAHAVDLVRQIADMNRGKFIDGEVEECHHSKFSIGVA
GYPEVHAEARDITSDIARLRDKVDAGAEYVITQMFFDNAKYFDFVRRCREAGITVPIIPG
IKPLSTLRHLEILPETFGVKLPEELVREVKAHPDGVREVGTEWAIAQSRELMAAGVPVLH
YYTMSRTTNIQKIVKAVF
>A0A0W8INI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria polaris|TrEMBL
MPIDTPHAGPAAALLQDFSLEMTGKDVPALEEAAAEIPPGTRINVTFLGNEDLAMRVAAA
RAVREHGFVPVPHLSARRLRSQDELEEFLAALAEVGAAEHVFVVGGDPETPEGPYEDSLS
VIRTGVLQQHGVRGVGVSGYPEGHPDIGDDVLWAALTDKTAAIREQGLEPEIITQFGFDK
DPVLEWLAEVRRRGVDAPVRIGVPGPAGVKRLLGYARRFGVGTSAGIVQKYGFSLTNLLG
TAGPDRFLRDLAAGHDPAVHGQVRLHFYTFGGLRATAEWVRGFGADGGTP
>A0A344WH62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp. CACIAM 19H1|TrEMBL
MTPPAIQLPTAENAVRVSFEFFPPKTEAMNARLWETIQRLEPMAPAFVSVTYGAGGSTRE
RTHDTVRRIVAETTLRPAAHLTCVSATKEEVLAVAEEYWQAGVRHIVALRGDPPAGMGAK
FEAHPGGFVDSVDLIRGLREHRPELGKCFEISVSCYPELHPESQGWDAEIGFLKAKQDAG
ADRAITQFFFEPEVYLAFLEKARAGGVTMPIVPGIMLQPNFNGLKRIAGLCGASIPSWLH
TLYDGLDEDEETRDLVTANVAADLCRKLQAQGVQDFHFYTLNRAGLALSTCRLLGLNPQS
AKAA
>A0A2T4B0K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma citrinoviride|TrEMBL
MDRITDKLAALPENAEYFSLEFFPPKTQMGFSNLRVRLQRMERALRPLFVNVTWGAGGST
AQKSLELAELCQRELGLTTCLHLTCTNMSQALIDQALDDARALGIRNILALRGDPPRAEY
RDADEPTGAASEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPY
LVDKVQAGADFIMTQLFFEIEAYEKFETRLRTHPSGAFKTIPILPGLMPIQSYAMIKRTT
KLSHAKMPDEIMARLNAVKGDDEKVKMVGVDILSELVEQIREIKSRTPGPKGFHFYTLNL
EKSVSFILERTKLIPDTTEEEEEAVVDESAVAAAAQRVIPKISVNGNVPPRAPSHTRTAR
RQSSVGSDPHNRVIVGRAATHPEWEASSTEAGIPAGSVNTRANTLAISEGEGALGREATW
DDFPNGRFGDARSPAYGEIDGYGVSLHMSVTQAVRLWGYPKVASDINDIFVRHIRGEISA
IPWSEEDLLPESSIIKTQLEALNRKGWWTVASQPAVNGLPSSDPTFGWGPASGFVFQKSF
VEFFLPSADWKKLYDKLTSAEVEEVVCFYASNAKGDFVSSDSTGGSGRVGASASTNAVTW
GVFPGKEIVTPTIIEEVSFRAWSEEAFGIWAEWAKVYGRGSDSQKLLDGIREDYWLVNII
HHDYVDTDALWRLLID
>A0A4R8EGC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buttiauxella sp. BIGb0552|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIAQDYWNSGIRHIVALRGD
LPPGGGKPDMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNYKQAHKFATMTNVRVPHWMAQMFE
GLDNDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A3A9AX43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium D16-34|TrEMBL
MRNVARIYSSAAQVAKKPISFEVFPPKGDLTHEVAREMAGHLAELHPDFISVTYSAGGGG
NKQATAAIASMIQDDFAVPTVAHLTCAGMDEAAYERAVSELQAFGVHNVLALRGDLPQGE
TDTQAVHQDGEMSARPFLYARDLTQRLVADGFCVGGAAYPEGHVTCFDDAANICHLKQKQ
DAGASFFITQLFFDNECFYRFREAALKAGVSAPLACGIMPFLSKAQIQRMVFMCGASLPA
PIIKLLARWESDPESLRQAGIEYACNQLVDLANHGVDGLHVYTMNQPDIARAACSALRES
GLV
>V7HAW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L2C089B000|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTIKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A3V2XNK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1Q7PZ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon 13_1_40CM_2_52_4|TrEMBL
MKGRVDAITIPALRNGEGDPSYPAGFRVTPQTRSLASAVIVRKTGAEAVPSLTCRDFRRS
DLDLVPSLFKKGLDNFLVVFGDPYPGYQIEDYDFRKTEDLIRGVLSVFDGQRPCIGAVTN
QYSKDQEREISRTLRKVDAGADYVVTNTAFDDRLVLDHADRLRSQGLKAPIFVQVSIPSG
LKNLLFVSRKFGIPVPEEVRQTLSRNPFGGGIQIAARAYTALRNEVSGIHFSYLHRSHNP
IPAYTHLLDAIETDGKLTVSIQAALRH
>A0A7Z0BEJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora jinlongensis|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTEAGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATDTTLLPMAHLTAVDHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWIRHPEGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAQFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGVEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARV
>A0A6I7QD79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneolaceae bacterium|TrEMBL
MKVIEHYDKATEPLISFEIIPPKRGGSVSDVFESLDRVVEAVRPPFIDVTYHAAEATVEE
QPDGSLKRVIRRKRPGTIGLCAAILHRYGIDPVPHLICEGFTKEESEDALIELNYLGIHN
VLAIRGDNTGSQISLNLNGTVNKYAIDLVRQIQNMNRGEYLEDIINAEPTNFCVGVAGYP
EKHFEAPNLDWDIKKLKDKIDAGAEYIVTQMFFDNSAYFRFVEKCRDYGITVPIVPGLKI
LTTTGHLKTLPKNFYLNLPDQLTEQIDANPDHVKQIGVEWAQKQSLELMENGAPGLHYYI
MGDPQPALDVIGYLQKK
>A0A6H2NNZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. LCM1.Bin17|TrEMBL
MGYRFRTAAQAGDFLVTAEVMPPKGGDPSHMLAMARGLKGRVHAVNVTDGSRAVMRMASL
AAAVLLQQEGVEAICQMACRDRNRIALQADLLGAHALGLRNLLTLTGDPVKAGDHPEARG
VFDLESVRLLKLIDQLNDGADSHGKALTDGPLDLFCGAAVDPQSRSWSGLQRRFEAKVQA
GAQFFQSQLITDFDRLAKFMDQIAAGSNRPVLAGIFLLKSAKNATFINRNVPGAQIPQII
VDRLAAAADPLQEGIKIASEQVKAARQICQGVHLMAVRREDLIPQILDLGEIGPITAAVP
AVIDQRDRSAVSLQP
>A0A3N6FS22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ADI97-07|TrEMBL
MRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVRA
TQQIAADSTLIPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
RGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDSDVRNFVDKCRAGADYAITQMFF
HPESYLQMRDRVVAAGCETPVIPEVMPLTSVKQLERFAQLSNASLPPALKDRILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A7L0I1X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenaria interpres|TrEMBL
MVNETQHTCSPSSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQESGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEAVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A353RPF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium|TrEMBL
MKISEFFEKEGKTTFSFELLPPLRGNSIQQVFNAIDRLKEFDPKY
>A0A3M2EFC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSVRPSVSFEFFPPKTLSASFRLWETVRELAPLRPSFVSVTYGAGGATRQRTHEAVEAIH
SHYGLNVAAHLTCVDQSRAETLAIADSYAAAGVREIVALRGDPPGGTGRFVPHPEGFRSS
VELVEALARDGRFRIRVGAYPERHPEAASADADIAWLRAKFEAGASAAITQFFFEAETFF
RFRDRCAAAGIDAPIVPGILPITNWQGVTAFARKCGASIPAWLADAFEKAMRDGREDLLA
KAVITELCSDLLEGGVDALHFYTLNQPAMTREICHALGIQPEAELSQVA
>A0A316H208|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter sp. AP02|TrEMBL
MNQYQLSRRSNIGERVKVSFEFFPPKNDDMEARLWDTIKRLEPLNPQFVSVTYGAGGTTR
ERTARTVRRILEESTLTPAAHMTCVDASRDEVDQVISEFAAMGVKRFVALRGDPKEGVGA
AYQPHPGGYANGAELVGALKGQGDFDISVSAYPEKHPESPDFATDFDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARKAGIYIPIVPGILPIHSFTQVANFASRCGAHVPAWLAERFD
GLDKDPQTHALIASAVAVEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSPVTPSS
AAA
>A0A543NK45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloactinospora alba|TrEMBL
MPGLRELLTDPAPSRPVITAECPVIDGGGLGEIASHVTRIAPYADAINATDNTAARAHAS
NVAVAIALKHLGVEPVLQVVCRDKNRLALQADIMGAAMHGVTTVSCLTGDDVTAGDEPET
RRVFDMDAPQLIHAASGLNRGTYLSGRKIDPAPQLFIGAVENPGAPPFAYRVRRGLKKAA
AGARFLQLQICYHSDRLAEFTQLAESTGLNRKTALLPSIALVGGAKALRYMDANVPGIHV
PQTVVERVENSSDPREAAYQLALEQAREALTMPGVRGLHITDFRRDDTLGRLCSDLGLPT
VRSAPEENALAV
>A0A3M1A6J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MKTPRVSFEFFPPQSLEASFRLWETVRALAPLRPDFVSVTYGAGGTTRDLTHEAVETIHR
HYGLNVAAHLTCVNASRAETMAIAERYARAGVTEIVALRGDPPKGEGRFVPHPEGFASSI
ELVEALAATGKFHIRVGAYPEGHPESADMKQNVEWLKRKFDAGASSAITQFFFEAESFFR
FRDACAAAGIDAPIIPGILPIENWQGVKRFAARCGARIPPRLDEMFATATRDGREDLLAT
AVCTELCTDLIEGGVEALHFYTLNKPALTRDVCHALGVSPEVVLENVA
>A0A258Z3T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuricurvum sp. 24-42-5|TrEMBL
MFESFIQKLRHGTFITLETTPSRSAQFAPTIEKIAALGLDSLVDGFSTTDNPLAKLKYNA
LFAAMKLQDRFGKPTLATMSMRDRNRIGLQSDLLGSNESGVRAILALTGDSAHYSDQPHS
KGVFEGNSNLLLDIITTLNSGTDMAEQKLIAPVQEIYPFAVI
>A0A3M1PXK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
RPTPGGYANAAELVAGLKRVADFEISVAAYPERHPESPTLAADLENLKRKQDAGATRAIT
QFFFEPELFFRFLDHARAFGITMEIVPGILPVTHVGQLKRFAAFCGASVPAWLDHLFEGL
DDRPETRALVAATVAGELCSRLYAGGVRHFHFYTLNRAPLVYAICHLMGLRPQDSAAAAV
RTAGREIAS
>A0A7J2Y344|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MVAEVGARRLRVGSRLEWVLGSGAFAVTAEIAPPASADPEEIRKVAALFRGTTDACNVTD
CQRALVKMSSLAASAIAMQEGVEPIMQLVLRDRNRIALQADLLGAAALGVRNVLCLKGDP
PQVGNEKEAPGVFDLTTEAMIATFRNLRDNGILHGGDKVDAPPKILIGAAANPFAGTPEE
SFANLRGKVTSGADFIQTQAIYDVDAFEEWMHLVRKEWLHERVYLLAGVIPLRSYKMAKF
MAEKVPGIVIPTDILERMRSAPDAKAEGRSIALRTIKALRKIEGIHGVHIMAVNWEEIVP
VLVREAGLYPRPAMPAGPL
>A0A062N8X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 796380-1375|TrEMBL
MKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGKARDIQDFEQFLEQA
QTANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGFRIGVAFNPFKYVE
AERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKAFLTKNNYSQQILACVMPLTLGRA
NFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKHLGFAGIHLSACHKP
EEQMLLESYIEQYRHLELNVLEELWNSLWQVTTGKEFSPEIVRFSRQPTSKQLIKYRQLH
VMHEAMFGSKIAKGVGRFIFKASFWENALIAKLLLKTEVLSKHSLVGCESCGQCRLGDTL
YICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVEQTEILKDKLIPTVSIE
TRGTSSWKNWYLGAEA
>A0A534LUD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MRRAFRKSLSATPLVLEIVPPSRRASEKAISALVDRVRDAVRTLGNLDGLNLPQVLEENH
QGQPFLRNLDPRDFAERLGDDLGVDPIVNNVVAHAPSRDGFRRWVKESLEDGLRSFVLVG
GTSSRVRYPGPSVLEANQILRAAAKGHPDVALGNITIPDRENEVDRLVEKTQAGCDFFTT
QVLFEAEPMATVLRAYGKRCAAMGLKPATVLLSFAPVSDYQDLEFLAWLGASVTPRTEEA
LVANGEAAPGRSSIDVARTLWSHLHAAAATSRPAVPLGVNVEEVSLHNFDLAVQIAREFP
AWRDAKSPPAAHV
>A0A6I3NC69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paludibacter sp|TrEMBL
MRVIDLINNSKTTAFSFEILPPLKGNSIDLVYKTIDLLRPFDPKYINITTHRSEIVYKET
GPNLFQRVAERHRPGTVAIAAAIQNKYKVNVVPHIICSGFSKSETEYALIDLQFLGITDL
LVLRGDKAKHDKAFIPGEEGHAHAIDLQQQINDFNSGKFMDGSIIKQPVSTFSYGVAGYP
EKHDEAPNLDSDIHWLKEKVRLGAEYVVTQMFFDNEKYYAFVERCRKEGITVPIIPGLKP
ITLMNQLTVLPKIFHVDIPEPLATELAKCKTDAEALEAGVEWCTMQAQDLKLHGVPSIHF
YTMMATQSVKRVAEKVY
>A0A816YSF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica napus|TrEMBL
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNVICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAYGIHFATEMCKKILAHGITTLHIYTLNVDKSAIGILMNL
GLIDESKITRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYSTLSDYQFMRPRARDKKLQQEWVVPLKGIEDVQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TLVEKSKAFSSITFMAVNKAENWVSNIGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNDYIDGDIFSVFA
>A0A842HJK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp. 7-48|TrEMBL
MNASKALSLEFFPPRDAAAQEKLSVAARRLSALNPAYVSVTFGAGGSTREGTAEAVRLMQ
GLGFDTAPHLSCVGSTRSVLADILDAYRNTGVRRVVALRGDPPSGMGIDSGDLHYAVDLV
RFIREYSGDWFHIEVAAYPEVHPQAKSAQSDLDHFVSKVNAGANAAITQYFFNADAYFDF
VDRAQAKGVNVPIVPGIMPITNQVQLLRFSDMCGAEVPRWIRQRLADYQGDLASIKAFGK
DVITHMCQRLLDGGVPGLHFYTLNTAEATLAIAHDLKLG
>A0A1H9RS59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus fusiformis|TrEMBL
MGLLEKLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESSVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLDDI
LATVEEQASVLLAGNPDGLLLETYYDFEELTATLNMLRAKTNIPIIAQVSMHEPGVLQNG
MSLNNALHELEILGADIVGVNCRLGPYHTIQAFEAVELPAKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVSEKHAKPEKIEI
VRDAEPAKFEPLHEKVKRERSVIVELDTPRHLEIDGFLEGAKQLYEAGADVVMMADNSLA
SPRISNIAMGALLKSTNGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDVLAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKIIEIYEATKHLQAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSEDALSRMKACGEDKERATLEGIAIAKELVEVAAQYFQGIYLITPFLRYDVTLELMKY
IEQLDEQKKGVSING
>A0A0K8Q8J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Hiyo6|TrEMBL
MTYGASGSNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELSEIIGELLDVGVRGILAL
RATSPRTAGRLLRVRCGTPRTSSNSSAGW
>U2ELH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. KLE 1732|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPGTIEHLMKYRPEYISCTYGAGGGNVGANRE
VCQMIRNAGTIPVTHFTVIKNTKEGIRQQLERYLADGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRNEFGDKFEIAVAGSPEGHIACRSLEADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A5N3S6W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio fortis|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSNEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELIQIADDYWANGIQSIVALRGD
IPPGGGAPEMYASDLVKLLKARHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAINNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A0H4W7W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rufibacter radiotolerans|TrEMBL
MKVTEHLHNATKTLFSFEILPPVKGTSIQSIYQGIDPLMEFNPPFINVTYHREEYVFKER
ENGLLEKITIRKRPGTVGICSAIMNKYHVDTVPHIICGGFSKEDTENALMDLNFLGIDNV
LLLRGDAVKTEPGFRPHKDGHAHASDLIQQVVQLNHGHYLDEEMENPVPTDFCIGVAGYP
EKHVEAPNLASDLKYLKQKVDLGADYVITQMFFDNKKFCDFVKACREAGINVPILPGLKP
ITAKSQLNVLPRYFNIDLPEDLVNTVEACKTSADVKQVGIEWTIQQCKELVEFGVPCLHF
YTMSKSEATAAVARAIF
>A0A160UPY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. G22|TrEMBL
MTDLTTPARAEGQDGHLQNGHLTSKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFV
SVTYGAGGSTRERTHSTITRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVG
LRGDPAGGIGTPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDT
LKAKVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAG
TSVPDWLAEKFDGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISH
LLGIRAKSAQKAA
>A0A4P7YJA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. TSH100|TrEMBL
MTAPTSALPSISFEFFPPKSEKMEQSLWQSIRRLAPLSPGFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGKYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPEAHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDAYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPAKLAETFEGLDD
DPETRHLVAATVAAEQCQALQAQGVNDFHFYTLNRSDLTIAICRMLGVKAKAAPAAAAVA
G
>A0A1Q8E904|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus cuniculi|TrEMBL
MVHTPSLSFEVFPPNPTAGNEKILSALRDMQDLAPHFISVTASNNKFNIEETTVRLADYI
HNDLAIPSIAHLPAIYLNKEQVFNILTALDQIGVHKILALRGDILPDVAPQTDFRYATDL
ISFIKDEAPHFDIIGACYPEKHPDSPNQVSDIKHLKKKVDAGCSSLVTQLFFDNDVFYDF
QEKCQLADIEVPILAGIMPIINRNQALRLLNTCENIRLPRKFRAILDKYEHDPESLRAAG
LAYAIDQIVDLVTQDVAGIHLYTMNNPQVAKHIHQATYSLFKHSAV
>A0A2K2U7A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubneribacter badeniensis|TrEMBL
MTTIRSIYRTARACGRRPVSFEIFPPKGDLTLDVAHDVAGQLAELAPDFISVTYSAGGSG
NKRATADVAQMIQRDFDVPAVAHLTCVGATEETIARAVDDLRAHGIDNVLALRGDAVGAD
EPGEYRYARDLISRLAEEGFCVGAAAYPEGHIACDDARANIEHLKQKQDAGASFFVTQLF
FDNEFFYRFWEAARNAGVTAPIACGIMPFLGKTQIQRMVFMCGASLPSPVVKLLARFEDR
PDDLRRAGIEYACAQLVDLDAHGVDGLHVYTMNQPDIARASMAALRAAWRA
>A0A1J6W387|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rossellomorea aquimaris|TrEMBL
MGTLLYSYGVDRCFEELNLSHPEEVYKVHRDYIEAGADIIQTNTYGANYEKLSRYGLEDS
VKEINTAAVRLAKKAADGSAYVVGTIGGIRAVKQNVSLEEIKRSFREQLYCLLLEGVDGI
LLETYYDFEELMTVLKVAKRETDLPVIAQVSLHETGVLQNGMKLKEALHQLELSGADVVG
INCRMGPYHMVASLEEVPIPKGSFLSVYPNASLPNYEEGRFYYSAEPGYFGDISNELRNQ
GARIIGGCCGTTPEHIRAVAKKLRSRIPVTEKKVKVTKSVEPISRPMNEKLIHQKVKEKK
TVIVELDPPKHLDTDLFFQGARALKEEGIDALTLADNPLASPRVSNAAIGTMVKERYDIS
PLIHITCRDRNLIGLQSHLMGLHTLGIHNILAITGDPAKIGDFPGAASVYDLSSLELIEL
IKQNNEGISFSGKSLRQKTQFSVGAAFNPNFRHLDASVKRLEKKITAGADYFISQPVFGV
EEMFQLYEATKHLNTPIFIGIMPLLSSRNAEFLHHEVPGIKVPEAARTRMKEAGKDPIHS
RAAGMEIAKELLDTALTLFNGIYLITPFVRYDMSIELLRHMKEKAGIEKEVPYGRHII
>A0A395YID9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea sp. AM58-8|TrEMBL
MRLLDKIKDHILLMDGAMGTYYNQQYGTELEAEEANLVHPEEITAIHKAYIEAGAELIRT
NTFAVNHLMFPKQEECKRAIHAAIACARQAVAESSREVEIAASIGPIRQTVTEDDENTIK
EYQFLINSMLAEGIHIFVFETMLELKWVQPLSEYCKSQCEESVVIVQFSLNPSGYTQYGF
GMKEIIDKLGQMETVDVFGFNCGVGAAHLRKLLEKQTFPKECMLSVLPNAGYQQELRGRM
HYGDDPEYYAKQMERMIPLGINIAGGCCGTTPEHIAALKKVLGGQAPQPKEVVEENADGE
SVSNAAPTDFISKLDRGEKVFVVELDAPFDAQMDKFSKGVYALKENGVDMITVSDSPLAR
SRADAALLAVYAKRLTDISVMPHVAMRDRNLIGLRSEILGAHANGIRDFLVITGDPVGPD
NRGKITGVFDVNSIRFMEYLQHMNEEIFPDQPVYYGGALNYAGNNIRAISGRMRKKMEAG
CAYFLTQPIFSEEDVQRVIELKEMTGAKIICGLMPLVSYRNALFMKNEMPGIHVNDEILN
RYDPEMSREEAEDTAVALCLDIAEALRGAADGFYLMTPFHRVGLVNRIINAIKQGE
>A0A7M3TPN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A371P390|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium endophyticum|TrEMBL
MASDDRSLVAALRAPAPSYSFEFFPPKDDDGEAVLWQTIADLEPLDPTFVSVTYGAGGTS
QERTVRITARIAEQTAMRPVGHLTLVAQTRGEIESVLKQYAAAGVDNVLALRGDPKGGPR
APWEPHPDGMTYAVDLVELAKELGGFEIGVAAFPEGHPDAASLDHDAEVLAAKARAGADY
AITQLFFRSSDYFGLVERVRALGSDIPIVPGIMPILNFAQVARMAELSGAAMPAEVLEQI
EPIADDKVAVRAKGIELATQLCRDLLAGGAPGLHFITLNRSRATREIFEQLRADGLV
>D6ARH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces filamentosus NRRL 15998|TrEMBL
MALGTASTRTDHARTVRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGPWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A1Z4MVZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolypothrix tenuis PCC 7101|TrEMBL
MPDTQIPTVLNAFRSAAQAGEFLITAEVAPPKGGDPKHMLDMAATLKGRVHAVNVTDGSR
AVLRMSSLVASAILLQHGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPDAKSVFDLEAVRLLQLIRNLNQGADSNEQPLSDGALDLFVGAAVDPQCASWSGLQS
RFERKLQAGAQFFQSQLITDFERLEKFMDKIAAGCNKPILAGIFLLKSAKNAQFINRCVP
GVNIPQHIIDRLAKAKHPLEEGVKIAAEQVQIAQQLCQGVHMMAVKREDLIPQILDLAGV
KPMNLVLTK
>A0A377KFN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYSGSTSRSEKCPGRFTQPETKSGCRSQPR
HYSVLLRCRKLPAFSRSLRLGRH
>A0A4C3NPQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MALRGDLPPGSGKPEIYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVD
AGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAW
MAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRP
GL
>A0A4R5K383|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. H9|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARHLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKEDLRSLLTQYKAAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESADHFHIEIAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQKLGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVASIQKFG
EEVITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A4V1D656|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychroserpens sp. NJDZ02|TrEMBL
MKVTEHITKGEGKTQFSFEILPPLKGQHIQSVFDNIDPLMEFKPPFIDVTYHREEYVYKD
LGDGLLKKQVVKKRPGTVGICAAIQNKYNVDAIPHILCGGFSKEDTENFLIDLDFLNIEN
VMALRGDAVKTETYFTPEKDGNVFASDLVKQVSELNHAKYLDEGLLNCSATDFCIGVGAY
PEKHMEAPSLDSDIHFLKKKINNGAEYIVTQMFFDNEKYFQFVDKCRAEGITVPIIPGLK
PISTRKQLNIIPHRFHVDLPEALIKAIIKCKTNAEVRQVGVEWCIQQSQELKKSGLPLLH
YYSMGKSDNIKAIAEAIF
>A0A355CKI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcoleaceae bacterium UBA10368|TrEMBL
MNRFRTACTTPGEFIITAEVTPPKGGDMTHTLAMAQQLKNRVHAINITDGSRAVLRMCPL
AVSAILLQHGIEPICQVACRDRNQIGLQADLMGAQALGIRNVLALTGDPVKAGDHPKAKS
VFDFEAVRLLQTIQKMNGGTDWNDKRLTDGVTDLFAGAAVDPQSPSWSGLQSRFEKKIEA
GAQFFQSQLITDFELLDKFMHQIAAGCNKPILAGIFLFKSAKNAEFIKKYVPGVHIPQET
IDRLAKAPEPLQEGIKIAAEQVKLARQICQGVHMMAVKREDLIPQILDLAGIEPVS
>A0A7C8X9G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSHDRPLSFEFFPTKTDAGHEKLMGVARQLASYKPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVNVPAAPHLSCVGDSKQDLRGLLDQYRSAGINRIVALRGDLPSGMGMSSGELRHANDL
VEFIRAETGDHFHIEVAAYPEMHPQARNFEDDLVNFARKANAGASSAITQYFFNADSYFY
FVERVQKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLGR
>A0A3A5L8X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium waimense|TrEMBL
MIAHQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKNFMQKARDLGHTEKVFTLC
GVGPLASAKTAKWIRNNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLGHILHDEITETQVDMVK
TAH
>A0A837KRC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus formosus|TrEMBL
MTTRKKDLRAYLKDHLLVGDGAMATQLHGLGVPVGVSFEELCLSNPRLVHEVHTSYYQAG
ARFLETNTYSANRDALSRYGLEHKVARINRLAVAIAREAAQDDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGVDGLILETFLDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYALTDAFSELKAAGADVIGLNCRLGPAELLRSFENTVIPEDALLSVFPNAGRLG
MTDGEYAFKSSPEYFGQSALRLREQGVRLIGGCCGTTPAHVKAIADALESLEPQARVNPT
IVAGDRPSISVQSTREREKPSIVERVKTATTIIVEFDPPRDLDADQFLHGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKSRHGIDPLLHLACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMDAAVARLEKKVEAGADYIMTQPVYDAESIRNVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSTEALERMKKVQGEAARQEGIAIAKELVDTAVRYFNGIYLITPFNYYE
MAAELIQYTRQQSSLVRMAQT
>A0A7H5R9V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDAIASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALLIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQPTPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEGRIEHWQNQVHTLEQWAPA
WQASWQMPGLPAVIFHPPQAAWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRRPLWATHLGAQVLHKVERAVKRPLVGCHTCGRCRLEDTLYVCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHCSSWPQWFQAATP
RRLSPQPAPRSQPES
>A0A4R1HVZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia endophytica|TrEMBL
MVYGPCGGVRDDLTCELGSVTCPFVDGPAVAWGGPVPSSHPVPGAFERSGGRPIVLADLT
VPPYDAGSLARCTTMLAGSCDALLVGQYHDQPDFPPTLLAALIGEAGGHPWVTLSCRDRN
RVVLEQDLAGLAAVGVDAVFCVTGDARAPGVRADVTQVFDLDGPRLAGLAAAAGLPVAVP
ESPDAPPREERAARLAEKRRAGAGAAVLNHVGSADRLAAFTSAARASGADLPVVAGVAVY
TDEPGARTLQAFPGLALDPERVEAVLAAPDPVEAGIEAAVAEAAELLAVPGVAGVNLSGR
GTSGGSERAAEIKAEVGRRIRGLLAA
>K0NN67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula toluolica (strain DSM 7467 / Tol2)|TrEMBL
MKLSQKLGKNFVITTELGPVKGVLADESLEKARDYLPLDGINIHDCPMGNLRINSISMAS
LIQNSLDVETVPHFTCRDRSLLGTQADLLGAHTLGIRNILVTTGDPPKHGPYPSKAVYDY
NTVDLIRLIKKMNNGLDYDEKEFGGSTDFNIACTAMPTSRKPEHEMEKMEKKISAGADFF
QTQVVYDSEKAVTFLKAARKLDKPILIGVMPLKSVKMARFMDKNVEGIDVPEDVISRMEN
QGATGIEITCDFIKDIIEYADGIHIMAMGDVKGTNHIIEFTRSLIAQ
>A0A1H2H8B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula phenolica|TrEMBL
MKTYSQLHEKLSRGEFAITGECGPPRGANKEVIDKKIKLLKGFVDAVNVTDNQTAIVRMS
SIAASAHLVAAGLEPVMQMVVRDRNRIAIQSDIMGAYSLGIKNILCLSGDHQKFGSQPEA
RNVFDIDSVNLIRTVRNMRDTGKDMSGFDLDVAPQMFIGAAANPFADPFEYRVIRLGKKF
DAGADFVQTQCIYNMGRFKEWIRLANEEGLTQKGYILGGVTPLRSAGMARYMNKKVAGMD
VPEEIIKRMDGVEKKCQADEGIKICLETIEALKELTGVHGVHIMAIEWEDAVARIVEQAG
LN
>A0A416HBB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eisenbergiella sp. OF01-20|TrEMBL
MIKDLFSEKKQLLSFEVFPPKKEDEFANAISVLDSLAGLQPDFISVTYGAGGSKSKKTVE
IASYIQNQLHIRALAHMTCVGSRKEDIDAVTAQLREAHVNHVLALRGDRPSYMSDEQFEG
RHFSHASDLIHYLGTNTELHIAGACYPEKHYEAGDTESDLIHLKEKCEAGAEFLITQLFF
DNDAFYRFLEKAGKSGIQIPVCAGIMPITSAKQLGTTVSLSGSAVPKQLADIIATYGDDP
ADMRKAGIDYAIKQILDLKAHHADGIHIYTMNKPKVAQEIAAAIR
>A0A399UL71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. LPMIX5|TrEMBL
MAPSSASSLNLAEARALLLSPLGPVARAGSNRNAVNVSFEFFPPKSDAAEANLWSAIRRL
EPLNPAFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIEGYKA
IGVDHIVALRGDPPGASGIGGAYTPRADGYANATELTAALNRIGGFEVTVGAYPEKHPES
PSIDHDIDVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVSNFAG
LKRMTAACGAALPDWLAGHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNR
AELVYAICRVLGVRETKAVA
>D5EJ13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coraliomargarita akajimensis (strain DSM 45221 / IAM 15411 / JCM 23193 / KCTC 12865 / 04OKA010-24)|TrEMBL
MSTLSIQDRLQQAAPLFSVEFFPPKSDESAGPLLRTAERLKAFSPDFASITYGAGGSTRS
RTLKYAQKLNDDFGYAMMPHLTCVGHSKDELRGIIQEFKEAGLKQIMALRGDPPKGETNF
TPHPDGLSYANELVHLIREEYPECAIGVAGYPEKHPEAPSMEIDLLNLKRKVDAGATFVT
TQLFFDNAVYFKFVDDCKRAGIHIPILPGLLSVTSYAQAKRFCEMCDATLPADLEAQLVA
AQDDKAAIEAIGIEWIANQAKELLEKGAPGIHLYVLNRAAPTIALMDKLQAAGFYKA
>A0A2T0M3Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella shujinwangii|TrEMBL
MEPLVPEGPHSPSALAPLLARPRYEVLPLPSVLDQTGALPEDTVVTVTASPRRGTGATVE
LCEKLAAQRLHAVPHLAARQCTGRGELREMLARLDGAGIEEVFVVGGDAAQPAGPYPDGL
ALLRAMADLGLLPARIGVPSYPEGHPSIPGPALWSALRAKQPFAHYTVTQLCLDGAAVCR
FTATLREEGVDLPVVAGVPGTVEARSLLTIGLRIGVGDSLRFLRGHTSAAGRILRPGGYR
PRRLLRTLDAELERNRCALAGLHFYTFNRVGATARWVRRAHRRATRERGSAA
>A0A257GE62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. PASSN1|TrEMBL
MTTTFDQLREARTALDTPLFAGLPGDIRVSFEFFPPRTDPLMEQLWEVVTTLAPLRPSFV
SVTYGAGGSTRDRTHGTVARIIKEARLPAAAHLTCVDATKAEIREVAESYWEAGVRHIVA
LRGDMGAPGVPFTPHPEGYANAAELVAGLKAIAPFEISVAAYPESHPDSPSAQADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGITAPVLPGILPVSNVAQTRKFAAACGAH
IPAWMDGLFEGLDHHPASRQLVAATVCAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPERPLMEQAA
>A0A097EH37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas taxi|TrEMBL
MTISVNQLEEAQIALKAPLYADVAGDIDVSFEFFPPKNEKMEEQLWDAVRTLEPLAPSFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATREEIDQVAEEYWAAGVRHIVA
LRGDPPAAGAKFASHPGGYENAAALVAGLKRLHPFEISVAAYPECHPDSPDMTADIDNLK
RKFDAGATRAITQFFHEPETFFRYRDQVAAAGIDAEIVPGIMPVTNFASVVRMSKMCGTE
VPAWMARLFDGLEDHPASRQLIAATLAAELSRKLYAGGVKSLHFYTLNRAELAFAICHLL
GVRSKPVASVAAA
>W5MEH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lepisosteus oculatus|TrEMBL
MVNELPQTDSSGQPWRCDSSGPSSSGGDSSKESSRCSTPILDTDRAERLRDKMRRRTDSG
DCWFSLEFFPPRTSSGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTA
VNYCGLETVLHLTCCNQTKQQITAHLSKAKHLGLKNIMALRGDPMGAEWEEEEGGFNYAT
DLVKHIRSEFGDYFDICVAGYPTGHPEAVTYEDDLKHLKEKVDVGADFIVTQLFFRPETF
LKFVKDCRAMGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIKQVIEPIKDNDAAIRN
YGIDQAVGMCRVLLKSGVVPGLHFYTLNREVATMEVLKQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKCSKEA
LLKMWGEELMNEESVFEVFTNYITAQPNCAGNKVMCLPWNEDPLAPETNLLKDQLEKVNR
RGVLTINSQPNINGSPSSDPVVGWGPPGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRV
NYHIVNVKGKNITNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWA
KLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLDSCLWQVIEDMFELLDSPAEH
>A0A7U4Z858|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktomarina temperata RCA23|TrEMBL
MTQISFEFFSPKTVTAAFSLSRAAETLAGFAPQFSSVTCSKDPAQTLDTLRALRRSGLER
LQAHVTCSTQQPADLPAYLKAAQEAGAEGLIALRGDTAPKGLDVTDLIACAKQNAMQDIF
VAAYPEVHPLAQSSQSDLDWLKRKQDAGATAAITQFFFHAEFFLRFRDRAAAQGITLPIT
PGILPVQNWTATQAIARSCGTSIAPDLAEGFARAEREGRAEMMAIAQASELCDSLIQNGV
EHLHFYTMNKAEVVSAICTALGKAPQQSLRRVA
>A0A7W7PK43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces olivoverticillatus|TrEMBL
MALGTASTRTDHARTVRELLASGERSYSFEFAAPRTERGERTLWDAIRRIEAVGPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSVAELRNVIGQYADVGIRNMLALR
GDPPGDPMGEWVRHPDGVAYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDVRHFVD
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCQTPIIPEIMPVTNVRQIERFAQLSNAAF
PPDLAERILAVQHDPAAVRSVGIEYATDLCARLMGEEIPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A7C8AUI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium|TrEMBL
MKIIDKINNGKQFISLEYFPPKEKTEWPAFFRTVDRLTRLNPLFASVTYGAGGSTHADSL
EIVTRLQKEHGQEVMAHLTCIGSAPDSVTHFLDGLSAAGVGNVLALRGDLPKEGSAASPS
PTLRYASDLVSFICSGYPAMGIGVAGYPEVHPEASSPRDDLARLKQKLDMGADFAITQLF
FDNSCYHKFVEEARDSGVTKPVIPGILPVVSLKVIKRIVSLCGSTIPADFLAELEEADRR
GGAAEVQKVGVAHARRQVQELLEAGVPGVHIYTLNRSEVVLDMVEGITPS
>A0A7X5F1Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pannonibacter sp. XCT-53|TrEMBL
MTASTFVRRSRLAERAPITASFEFFPPKSDKMEASLWSTVERLAPLNPSFVSVTYGAGGS
TRERTHRTVERLLKETHLLPAAHLTCVGASRAEVDAVIQDYWDIGVRHIVALRGDPQEGL
GARYQPRADGYAYASDLVAGLRAIGDFEVSVSGYPERHPESADWSVEIDNLKRKVDAGAT
RVITQYFFDNDLFESYLERIAKAGLSIPVVPGILPIHNFEQTMVFSAKCGTSIPHWLARR
FSGLNEDAETRKLVGAAVAYEQVMDLVDRGISDFHFYTMNRADLTYAICHMLGMGQAEGT
RQAA
>A0A8J3MGI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catellatospora sp. TT07R-123|TrEMBL
MTLRAPSTMPGPRPTVRDLLSSGEPTFSFEFFPPKTPDGERLLWQAIRELESLQPSFVSI
TYGAGGSTRDTTVQLTERIATETTLLPLGHLTAVNHSVAELRHVIGHYSDAGVRNVLALR
GDPPGSDPQAPWTAHPEGLHYAEELVRLLKESGDYCVGVAAFPEKHPRSPDLDSDVRHFV
RKCRAGADYAITQFFFNWEDWARLRDAVHASGCEVPIIPGVMPVTNVSQIERMAQLSGAV
FPADLAQRLRAVADDPQAVRAIGVEFATELCTKLLAEGAPGLHFITLNRSTATREVWQRL
RVGATV
>A0A143YMI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus flocculiformis|TrEMBL
MKIREMISKGEPTVSFEIFPPKSSYALETVFDTLTELKDLHPDFISVTYGAGGTAQSNTV
EIASRIKKDFGIESIAHLTGCTSTKEGMKRTLASIKDSGIENILALRGDIPQEKLADKNW
NPEYRYASELIDDIKAAGDFSIGAACYPEGHVDSINKVDDLKNLKRKMDHGADFMITQLF
YDNDLFYQFKEKLDLVGIEQPVIAGILPVLNIKQVKRIQEISGCNLPPKFLRILDRYAHD
PASLQEAGIAYAVDQIIDLLSSGVDGVHIYTMNKPDATRRIMENISCVRKAVCRKEPQR
>A0A0D0YRL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus gattii VGIV IND107|TrEMBL
MKITEKLQKAEKEGRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALKEAKSHGCQNILALRGDPVAGTST
WEPTPGGFMNAVDLVRYIHKHYPGDFCVAVAGFPQGHPETPDTPEGRAQEMKWLKAKVDA
GAEFIFTQMFYDTSIFFDWVKRVREAGINVPIVPGIMPIQNWEKFEKWVQRENIIVPSHF
YEALNPVRGDDERVRQVGTKLVADMCKTILQNKEAGIKGLHIYTLNLEKGARMLLKELGF
EGRREQIAPLPWRPSLTPSRREETIRPIFWANRTRSYLSRTADWDEFPNGRWGDSRSPAY
GDLDGYPVSIGITAPDAYNLWGHPTTSFDLHTLFARFCRGDLVKLPWSTQPPASETSLII
EQLAKMNELGYLTINSQPAVDGVRSDDKVHGWGPAGGYVYQKAYLEFFVSPDLLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWAHLYPAGSPSRKLITDTMNTSYLVNIVANDFRDGMSIFEPFLLNQTTVGKVVEGV
KGTVEGIVEGVKGVVSA
>A0A1G0CFH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fluviicola sp. RIFCSPHIGHO2_12_FULL_43_24|TrEMBL
MKVIEHINRAKDTLFSFEILPPLKGATIQSIYDGIDPLMEFKPRFINVTYHREEFIYKER
ENGLLEKIAIRKRPGTVGICAAIMNKYQVDAVPHLICGGFSKEETENALIDLHFLGIDNV
LALRGDSIKTESTFKPHPEGHRYAVELIQQIAEMNDGRYFVDDVQLAPTDFCMGAAGYPE
KHFEAMNLSTDLQYLKAKVDAGAEYVVTQMFFDNQKYFDFVDACRAAGITVPIIPGLKPI
KTMNHIAFLPKVFHIDFPEALSNELLKCKSSADVNQVGIEWGIQQSKELKAAKVPCIHYY
TMSTSDTVKKIASQIF
>C0XJE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus hilgardii (strain ATCC 8290 / DSM 20176 / CCUG 30140 / JCM 1155 / KCTC 3500 / NBRC 15886 / NCIMB 8040 / NRRL B-1843 / 9)|TrEMBL
NPDFISVTLGAGGSDHYTGTVSIADLIQNQLNIPAVAHVPGLYQTESQVLNLLDHLSGIN
VKNILALRGDKIPGKEPVGVFNHANELVSFVHKNRPDFSIASACYPDCHAEANGFVDDIA
HLKEKVDAGANHLISQLFFDNQSFYDFKEKTEIAGINVPIEAGIMPCTNKKQIERITQIT
GVPLPKKFSAILDRYQDSKQAMKDAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIW
DATKSVFEAANQKKTEKASNH
>A0A636NZM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Guildford|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3D9HRY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aestuariispira insulae|TrEMBL
MSELNISFEIFPPHLVDADDALVRDAGILQGYDPAFISVTYGAGGSKRDRSERIVDKLLD
RNHPNLAAHLTAAGHSRESVCELLSGWWDKGLRHIVAIRGDAAGDDDIACAAELTEIIRD
VADFEVSVSAYPERHPKSVSWDAELDHLKRKFEAGATRAITQYFFDPDLFLRYRDRVAAA
GITAPIVPGILPVRSIEQVKRFSKACGASVPQWLEDRFTGLDQCPDAVTPVAVATIVELV
SNLRREGVEDFHLYTLNRVPEAVAVCHSLGITPNRKEAA
>A0A0R2P9T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR86 cluster bacterium BACL1 MAG-120507-bin14|TrEMBL
MKISYEFYPPKDLNYQKIIEEYSLLSNFGPRFISITYGALGSSQEKSVGLIKAFKESVDV
EVVAHLTLVGKSKQELSFIVDEFSSMGVTKIVALRGDVAEGSFIAHQDGFQNTAEFVDFL
AKKKMEVFVSAYPEPHPDSKGFDFDVRLLKDKTLAGSRQSISQFCFSMHEYQRLVDAIKD
QNIQNDLTAGIMPIYNIASLCSMAERCGIKIPPEIIGQFSEDPQKNEQASIKICIQQLED
LQAMGINNFHFYTLNQSSLLKKIFNEIGF
>A0A162J7F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium ljungdahlii|TrEMBL
MSLLKEAFEKGEFAITAEMAPPKGTDLSHLIECAKKIKGRVQGVNVTDFQSATLKATSLA
TCKVLKDAGLEPVFQITGRDRNRIAIQGELLSAGVFGIENVLALTGDYTATGDHPGAKPV
YDLDSVGILQVASILNGGKDMGGTELKGKPDFFLGACVTPRYDPLELQVIKMKKKIKAGA
KFFQTQAVYDMETLKKFKEETKAQGVDAKVMVGIIPLKSAGMAKYMNKNVPGIFVPDELI
DRMKNAEDKVQEGIKIAGEFIKTVKESGLCDGVHIMAIGAEENVPLILDEAGL
>D0RSQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. 2_1_36FAA|TrEMBL
MVRHHTPSLSFEVFPPNPAVGNEKIIQALREMQDIAPHYISVTASNNKFNIEETTVRLAD
FIYNDLKIPTIAHLPAVYLTKEMVLDTLQALDKVGVHKILALRGDIFPDVAPKDDFKYAT
DLIEYIKEEAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDIPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGVHLYTMNNAATAHHIYQATHTFFS
>A0A4P7FBK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beijerinckiaceae bacterium|TrEMBL
MQSCSFPRASRTVCPDISVSFEFFPPATEAMEATLWDSIKRLAPLGPSFVSVTYGAGGST
RERTHATVARIVNETSVKPAAHLTCVAAARNEIDAIVRDYWDAGVRHIVALRGDPQDGPG
TKFRPHPDGYTNSAALVAGIKRVADFEISVATYPEGHPESISADADIDVLQAKIDAGANR
AITQFFFENDRYLRFVDKVRARGIDVPIVPGIVPVQNFKQTANFAKKAGASVPQWLADRF
EGLDDDPQTRRLIAATVAAEQVLDLVDHGIRDFHFYTMNRADLVYAICHLLGLRPKLEQE
AA
>A0A8B4NCZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter nosocomialis|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYSVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KKAKSFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDS
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYVEQYRHLELNVLEELWNSLWQVT
TGKEFSPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALVAK
VLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKEKLIPTVAIETRGTSSWKNWYLGAEA
>A0A7K7T802|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sapayoa aenigma|TrEMBL
MVNETQHTCSSSSRSDGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQEAGDRWFS
LEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCG
LETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDLVKH
IRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQPETFLKFMK
DCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVEL
AVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGILT
INSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNYHIV
NVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKLYEE
ESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A7GSV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)|TrEMBL
MKLLDLLSKGIVIGDGAIGTLLHSHGLQSSFEELNISDPDLIVSIHKQYVAAGADVIQTN
TYGANEAKLRTYGLENQVVQINRAAVKLAKAAAKEQNAILGTIGGMKHIGAVTTTNIERE
FMLLEQAGALIEEEVDGLLLETFYDEFELIHAIKVLRKQTDIPIVAQLALHEAGTTQNGN
DVNEILAQLIHNGANVVGLNCQLGPLPMTEALKMISIPKDGYLSAYPNAGLPNYIEGRYI
YEGSPAYFETMTPKFIEQGVRLLGGCCGTTPAHIERMKRAIANQVPVIEKTVVSRPPILH
THSERFRTHSTLAEKAKKQTTVVVELDPPKTLDTQRFFEGAKALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSVLGMEEVLALTGDPARVG
DFPGATSVYDVSSIELIKMIQEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDKALIYEVYKETKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPDQVRERMREHETEADAIEEGISIAQELIDEALKYFRGIYLITPFLKYEITEHLVKYIK
EKQEVREEVTNETN
>A0A507SN92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. SKL71187|TrEMBL
MSQFLNQLQNNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGANVIQT
NTYGANFEKLKTFGLEHRVKEIHKAAVQIAKRAAHHDTFILGTVGGFRGVRQDDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELKSIVVATRRKYEIPIIAQLTASNTNYLVDG
TEINDALKQLVACGANVVGLNCHHGPHHMQRSFSHIELPDNAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIRYIKTAVQGLTPIKDKKVVPITKKS
NHKPTKVVKQNLTSKVKNGPTVIVELDTPKHLDTDTFFENVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQQYDIEPLVHVTCRDRNLIGLQSHLLGLSLIDVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A7C7VI09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfarculaceae bacterium|TrEMBL
MENENKKTRVLVIGSEAVYQEMIGKSLDEFEVLSATSEDEGLTLARKERPDAIVLGYLEP
RGTAYGLHRKLRSGWITKNTPLLIVEMGGDENSDKRWTRQEALEMDADDYITISADDSAS
ISLLKETIGLTEKITVRMDERASTLKGKLLEPNDFCITWEQIPGRGAFEIAHEEVLDNVA
KAAAGGKVDAISVTDNPGGNPALSTEMLCVQIKKAGMEPLVHLACRDKNRSEIESLLCGM
AAEGIKNVLVLTGDYSGSDAFEGLAKPVFDLDPPNVLRLVEKMNDGLEHKAGRKTIKLAA
TDLYAGACVSPFKKLESELMAQYAKLKKKIEAGAKFVIPQLGYDARKFHEILTWLKVNNY
NVPVMMNIYVLPFGTGRFMNGNGIPGCIVTDKQVAELAEEKKAADKGKAAMLLKAAKMYA
LGKGMGMGGAHIAGHGITYEQVEYIIDKGEELAANWESLVAEFDYPQEDGFYLFEKDEKT
GLNTEVYAERMSKPKAPLMYKFTRLAHHMIFEEKSPVFKILKPVLGWVDNSKLPKHIMDY
CEHMAKVSMFNCMNCGDCALFDTAYVCPMSQCPKSQRNGPCGGSYEGWCEVY
>A0A8F8IW82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. K1/93|TrEMBL
MTSTPDTGRSDVSISFEFFPPKTPDMEGQLWAAITELTEWQPEFVSVTYGAGGSTKAPTL
NTVRRMIAETPLPTASHLTCVSATREDTHRVVDELRAAGVRHFVALRGDPPGGIGTAYQP
HPGGYENAAALVAGLRDIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDVFETYMERVRAAGIAIPVLPGIMPIQNLTQLKRFAGMCGTSIPSYLDERFAGLDD
KPEERAKVAADVAAEQIEDLVRRGHREFHLYTMNRAPLVGAVLERLGFKRTKIAAAAGAA
A
>A0A359F000|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidaminococcaceae bacterium|TrEMBL
MKIIDHLKERRAGISCELFPPKKGTELANALEIVHTIAEKGPSFISVTYGAGGSNVGQAV
AVAAEVKKCGVPSMAHLTCINADESSIEAVLEQMRTNGIDNILALRGDLPEGQTLEHAEY
QHASDLAKKIKSFGDFCVGGACYPEGHPESANLNDDIEKLKIKVDNGVEFLVTQMFFDND
VMYNYMYRLLAHGITVPVVPGVMPVTNAKQIQHICKLSGTKLPLRFRAIVEKYGNDPEAM
KQAGINYAVAQVLDLLANGFMDVHVYTMNKPDIIGGILDNLSCIVKR
>A0A0N0CSV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MPLQYSFEITPNIDQANLDGLLELNPEFISITDRNHDMDNLLQSIKIADYIHANSSVDVV
IHLTGIDKDEKRVQEMIDLMQKHDIHSVLALRGDKLSQNDRAVTFPHADRLVEFINQKYP
HVNISGTCYLNSSDEEMKWLRQKIKKGCTNLISQFGFDVNDYVDYLNQIEIDTPIWFGIM
SIISKSQAQKMLKLTHSTAPDELNTLMNQHDDEFGEDGVQYTVGMINKIRQAGAKHIHLY
SLNNAANTKKIINKI
>A0A3N6F026|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ADI96-02|TrEMBL
MALGTPSTRTDHARTVRDLLATGKASYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQRIAADTTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHAQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPQDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFAQLSNASV
PASLKERILAAKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYENLG
LHRQS
>A0A1L8D0I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carboxydothermus islandicus|TrEMBL
MITESRLEKLFAEGHFVVTAEIGPPKNSNGEAVRKHARNLKNYIDGANLTDNQTAVVRLS
SIAAGFHVLSEGLDPIIQMTCRDRNRIGLQSDLLGAYSLGIRNVLALTGDHQSFGNHPTA
KNVYDLDSIQLIQTIKKLRDEKQFLSGEPIKEHEPRFFIGAVENPFGDPFEFRVLRLEKK
IEAGAQFIQTQCIFDMERFERFMEMVRERGLHERAYILAGITPLKSAKAAKYMKNVAGMI
MPDHIIERMEKAEDQKEEGVKIAVEMIEHLKNVKGVAGVHIMAIAWEDIVPVIVERAGLL
PRPEV
>A0A858Q4H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcus geothermalis|TrEMBL
MKTQQKYPRVFSFEFFPPKTEEAAENLRRTLGKLAPLKPRFCSVTFGAGGSTREKTFETA
LEIQQTTGIECAPHLSCIASTRQSIREILEAYRSHGIRHIVALRGDMPSGMLSAGEFRYA
NELVAFIRSETGNHFHIDVACYPEVHPQAASAESDLKNFKRKVDAGADSAITQYFYNPEA
YFRFVDDCERLGIDIPIVPGIMPITNYSQLARFSDMCGADIPRWIRKRLEAFGDDRKSIR
AFGLDVVADLCRRLLERGAPGLHFYTLNRADASLDVWNALGLGSA
>A0A2C9ZAG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis subsp. higo|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYGIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A243R3J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces swartbergensis|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDRVSAAGCDTPIIPEVMPIASVRSLERIPSLTNAAF
PPALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHRPQA
>A0A1I5PH19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarcicella hirudinis|TrEMBL
MTKITQYIEKAKGKTLFSIEIIPPVKGESIQNLMNNIDPLMEFKPPFIEVTYHREEYIEK
VVDGRVTKIPTRKRPGTVGICSSLMQRYKVDAVPHVICGGFTKEETEDFLFDLHYLGIEN
VLVLRGDPIKGAAAFTPEKGGHAYASDLVEQVVNMNKGILLHEETESFPTNFCIGVAGYP
EKHFEAPNFSTDFTYLKQKIELGADYIVTQMFFDNQKYFDFVNKCRAEGITVPIIPGLKP
LTTKKQLTVLPRIFHLDMPEDLVNAAMDCKTDKDVKQVGIEWGIKQCKELIEFGAPILHF
YTMGKSDNIRAIAEGIF
>A0A4D4KUA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces violaceusniger|TrEMBL
MALGNASTRTDRARTVRDLLASGEQSYSFEFSAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSRAELRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWVQHPDGLTYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATKLCARLMAEEIPGLHFITLNHSTATLEIYENLG
LHQRS
>W1QL71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ogataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1)|TrEMBL
MSIKISEKIKTLGPNDPFFSFEFFPPKTENGLRNLYARLTRMSLLGPLFVTVTWGAGGTT
AHKTLDLAVTCQQELGLTTCLHLTCTNTSKEVIDDALERAKKAGIRNVLALRGDPPRDGV
DPERHGHFKYAVDLVRYIREEHGDYFCVGVAGYPEGHVEGADNSDQDMKKDLPYLVEKVN
AGADFLVTQMFYDADKFVHYVKTVRSTEEINNKDLIIIPGLMPINGYSIFQRASKLSHAS
IPEPLLEKFPEDIQNDDDKVKEIGVDVLSEMISKIHKDTNGEIRGFHFYTLNLEKSIAQI
INKNELLSQVLKKKEEEEELEEETVSDEDIDEATTTAKRAAYADRFRQVNNQVIVDAPMR
RSGARNSMSQVKTIVSISSGKGTLGKDATWDDFPNGRFGDSRSPAYGEIDGYGPSLKMTS
TKAYELWGYPESLKDISKIFTNYLSGKINALPWSELGLNPETALIQEELIRLNELNWFTV
SSQPATNCSKSSDKIFGWGPKNGYVYQKAFVEMFISKKDWETLLPRLNANEYVTYYVSDS
RGGYASNLPGQKSNCVTWGVFPDREIVQTTIIEEESFRAWSEEAFNIWREWQMLYARGSV
SHKLISQVLEQYLLVSVIHHDYPNEQALWELLLEE
>A0A674CF46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmo trutta|TrEMBL
MVNQVQRVEDTWRTCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKAKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKMDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPDEIMRVIEPIKDNDAAIR
NYGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWNEDPRRTLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKNELDKVN
RRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPQEEQPAEQP
NDEQSDKEQPGK
>A0A845LVB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidaminobacter sp|TrEMBL
MKIRDMLLTTRPTVSFEIFPPKANYPIETIYETIEALKDLRPDFISVTYGAGGTSQDNTI
EIASKIKNTYGIESIAHLTCVTSSRSSMIETLEKIRASGVENILALRGDIPQALLDDKSW
TPEYRYAYELIEDIHKFDNFSIGGACYPEGHIESRNKIDDLKNLKFKTKTGLDFLITQLF
FDNELFYQFREKMELLGIKTPVLAGILPVLNINQIKKIQELSGCNLPPKFMRILDKYEHN
PEALQEAGIAYAVDQIIDLMSSGSVDGIHLYTMNRPEPTRRIMESIGSIRKALSTRKEG
>A0A4R4RG83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiangella ureilytica|TrEMBL
MALGLPSTMPGGARTIRELLASGGRSFSFEFFAPKNERAETVFWQTMRDLERLQPTFVSV
TYGAGGTTRDSTVRVTEGIARDTTLTVVGHLAAVDHSVAELRNVIGQYADAGVRNFLAVR
GDPPGDPRGEWVKHPEGYEYSEELVRLLRSTGDFCVGVAAFPEKHPRSPDVETDARFLVR
KFRAGADYAITQMFFDADDYLRLRDRVAAAGGEAPIIPGVMPVTNVRQIERFAVLSGMDF
PRPLAERLLAVEDDPEAVRAIGVEVATDLCERLLAEGAPGLHFITLNRSTATREIYQNLG
VAALS
>A0A087H529|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabis alpina|TrEMBL
MKVIDKIQALSDEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVDGGFGCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEDNGLATNEAYQSDLEYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGIKCPIVPGIMPINNYRGFLRMTGFCKTK
IPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALTDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGNLKSSPWSELDGLQPE
TKIINDQLVKINSKGFLTINSQPSVNAEKSDSSTVGWGGPGGYVYQKAYLEFFCSKDKLD
AVVEKCKALPCITYIAVNNGETWVSNTAQSDVNAVTWGVFPAKEIIQPTIVDPASFKIWK
DEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIFAVFAGL
>A0A316MKL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrionaceae bacterium|TrEMBL
MKILDLIRQRSTPFYSLEFFPPKDREEWPAFFERVVRLKAMNPLFASVTCGAGGSVQSNT
LEIATRLKRDHDVEPMPHLTCVSAKEEDIARSLEEFRNAGLDNLLALRGDRPRDAGPEWR
PGTFSCAEELVRFIRSRGGNFGVGVAGYPAPHPESSSFYHDREYLRRKIETGADFVITQL
FFDTREYFELVTRLRGMGIDVPVIPGVLPIQSLASIRRTLSLCGANIPGKFYLELEEAHD
RGGTEAVKETGLRFAVAQIRRLIDGGAPGIHLYTLNRAGLCLRIAEEVGRL
>A0A086N498|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces mutabilis|TrEMBL
MRDILAAGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVKE
TQQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWVPHP
RGLTYAAELVELIKDSGDFCVGVAAFPEMHPRSADWDADVRHFVDKCRAGADYAITQMFF
QPESYLRLRDRVGAAGCDTPVIPEIMPVTSVKMLERLPKLSNASIPAELKERILEAKDDP
AAVRSTGIDFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGLHHSSRA
>A0A5M6BJI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus seminalis|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPS
>A0A238WZW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter mucosus|TrEMBL
MRREACLLLLRLTGYELVLYMKVTEHLTRANGKTLFSFEVLPPKKGENIKNLFSNIEPLM
EFNPPFIDVTYHREEYVYRQHPNGFLEKKTVRKRPGTVGICAAIKNRFDVDTVPHLICGG
FSKEETENALIDLHFLGIDNVLALRGDPIKSEGHFKPDPDGHAYAADLIGQVANLNKGEY
LDEEQDETWATNFCIGTAGYPEKHFESPNYGADLRYLKHKVDRGAEYIVTQMFFDNEQFF
NFEKRCREAGITVPIIPGLKPLTTKSQLTMLPRSFYLNIPEELADAVHLAPDNPAAREIG
IEWCINQSKELMAHGVPCLHYYSMGKSESIRRVAAALF
>A0A372DYZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp. CCM 8763|TrEMBL
MKVTEHLTRAEGKTLFSFEVLPPKKGEDIQTLFSNIEPLLEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFTKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFVPEPDGHSYACDLIGQVSDLNKGAYLDEEQDDTWATDFCIGTAGY
PEKHFESPNYGADLRYLKHKVDRGAEYIVTQMFFDNEQFFAFERRCREAGIMVPIIPGLK
PLTTKGQLTMLPRTFYLNLPEELADAVHLAPDNAAARQIGLEWCINQSRELMAHGVPCLH
YYSMGKSDSIRQVAAALF
>A0A433XM14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arsenicitalea aurantiaca|TrEMBL
MTEIHEQARASRLVAAARPPLALSFEFFPPKTDAMEQRFWESLARLAPLQPRFVSVTYGA
GGTTRERTLRMVSAIKSESGVDAAAHLTCVGASREEVDGVVRGYAAAGVNRIVALRGDPP
EGVGQPFVPHPEGYRNAAELVAGIRALGDFDISVAAYPEKHPQSPNWQADIDNLKRKLDA
GADRAITQMFFDNGDYLRFLERARAAGITAPIVPGIQPIHSFKQIAGFAARCGAGIPDWL
AERFEGLEEDPETHALVAAAVAAEQVLELVDEGVTEFHFYTLNRSNLVLALARLLGVRPD
>A0A432FBT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquificaceae bacterium|TrEMBL
GVEYAISQCEELLDYGVDGFHFYTLNRPDATKEIIEALKDKIFSLRKV
>A0A0K0FYG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strongyloides venezuelensis|TrEMBL
MAPNLDDFQNNEVKFNLDDNTLGLKRNASSVYSFIDESEVSTYTPLIKRINNQIESGVPF
FSLEFFPPKTANGVANFINRLDRFRDGGTFFLDVTWHASSDPANLDKETSSSSIARCVLD
YCRIDTMLHMTCTQYTKEQTLSHIKQCKDIGLRNILALKGDLPDDPNTSLDQRQKSKYYA
LDMIKWIKESYGDYFTIACSGYPLGHPDAESYTSDLKYLKAKVDAGADFIVTQLFFEVET
FEKFVRDCREIGIKVPIIPGIMPIQGYASIKRIAELSKLLIPQSILDDLEAIKHNDEAVL
KYGIDRAVKMCSQILDKKVAPSLHMYTMNREGPTREILQKLGLWKQYHIKPLPWKPHGGH
HPLRCKEDVRPIFWSARPKSYIFRTREWDDFPNGRWGHSSSPAFNDLKEYYMFYLNVSNK
DKELQMYGDKLYSLEDVQKVFVNFLKQEENENGVKVTCLPWNEDEKGISFETNLIKDQLI
WANENGFLTINSQPHVNGAPSSDPIVGWGKQGGYVYQRAYLEFFTKKENAQMLVDIIDSR
YSERINYHVIDKTGKYERFNYNGTNPIALTFGIFAGSEVAQPTVVDPLSFRVWKDEAFDV
FNIWSSIYPPESKCCETLKFLHDSYVLMTLVDNEYVKPTIIYDLLKEIV
>A0A1Q7G4A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon 13_1_40CM_4_38_7|TrEMBL
MTITYELNPPKVIQDTVLSHEELQNSVNKLKAKAFEVSNVCNSIHVTDSVLGIPRISPIT
IGVFIRNSNDKIELSASVRVRDRNLTSLTQTICDAILLDLNAVLILKGDPPPAGPKDSKL
VPSEVVKQFNEQGFGKKIDLFLSLPSNPNFEKIHKKIEAQPKGFVTQVISSQDQITKIVD
KLKPQGFKIIPCILLPSEKNLQSAKRLNFDWSNYSNDVVGFIKEAHKISGNVLISSPNDF
KRALEVLKKLT
>A0A444CNL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensete ventricosum|TrEMBL
MSAAINLQVHHIRAKYGDYFGITVAGYPVDLLLSHLCLSFEQVDAGADLIITQLFYDTDT
FLKFVNDCHQIGITCPIVPGIMPINNYKGFLRMTGFCKTKVSTVVLYLLSLLLLWKFSIL
>A0A8B5XWQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peribacillus simplex|TrEMBL
MNFRKEVKERMLVGEGAMGTLLYSNGIDQCYEELNCTNPDQIESIHRAYLEAGADILQSN
TYGANFNKLKRHGLEDEVSRINRQGVILAKKAAKGKAYVFGTIGAQRSIRKSDLSLEEIK
RGFREQLYSLLMENPDGILLETFYDLEELETVLQIVKNETGLPIIANVSMHELGNLQNGI
HLNEAFQKLEQLGADVVGVNCRLGPHHMIRALEEVSLPKQASIAIYPNASLPDYVDGRLV
YKAVPEYFGSSALELREQGATIIGGCCGTTPLHIQAVKNAIGSLAPVKEKFTKSREIEII
EVNDRELELPLYEKAKTERTILVELDPPKKLGIESFMTGAEVLKKAGVDSITLADNSLAS
PRISNDALANLLKNQLNIKPMVHITCRDRNLIGLQSHLMGLQTVGLNEILIITGDPSKIG
DFPGATSVYDLSSFDLISMVKQFNEGLSYSGQSLGQRANFKIAAAFNPNVKYLDKAVLRM
EKKIACGAQSFLTQPIYSVEQIEEVYEATKHLDTPIFIGIMPLTSTRNAEFIHNEIPGIK
LPDNVRRAMALAGDDPVKSRIEGVNIARELVDAAREKFKGIYLITPFLRYEMTAELTKYI
RKVDSKHTSEVAVHE
>A0A1I5Q2V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salibacterium halotolerans|TrEMBL
MNIVGELEKRVLVGDGAMGTYLYDKGYSGSFESLNVTEPDVIQRVHREYVDAGADIIQSN
TYAANDVKLKKYSLEHKVESINREGMRLAREAAGSRAFAAATVGGIAGIQPLDISVETIR
EAYRRQVETLLEENPDVFILETFYDWKELLDTVRLLRGMTDIPIIAQAALGEVGVMHGGI
PVTEVFQELQKEGADVAGLNCRMGPYHLIQSFERVPLMKGVYYSAYPNASLPDLDDGRFV
YQSNPDYFYQRALDLKKEGVRIIGGCCGTTPDHIAWTAKAVKNSTPLAEKPHTLEMVQEI
PAASRIHPPKQRLNAVNPDRPSVIVELDPPKKLTTEKFIRGAEALYEAGADAVTMADNSL
ASPRIDNLAMAAAVQNRTKARPLLHLACRDRNLIGIQSHLLGLHTMGIQDVLAVTGDPSK
VGDFPGATSVYDMNSTKLISLIKEMNEGRSYSGNSLGEKTSFTVAAAFNPNVRNLHKAVQ
RLEKKIDAGADYFMTQPVYAKEQFETIYKEVKHLSTPIYIGIMPLVSSRNAEFLHNEVPG
IQLTEEIRVRMSAGGEDRATAQAEGLAISKELIDEALRYFNGVYLITPFLRFDMTAELTD
YVRKKNNNL
>A0A7U4BPC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii TYTH-1|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A7J5ZIU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ameiurus melas|TrEMBL
MKMKRAHPLKSSFAEESNGGQDETERERKRKREDDGDQRGRTGVMVNQREENGLLWIKSD
SSGASNSGESSKDSSKESSRCSTPVGESDRGNRLRDKMRRRIESGDWWFSLEFFPPRTAG
GAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCC
KQTKEKLTFYLNKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAVDLVKHIRSEFDDYFD
ICVAGYPTGHPEAESYEEDLKRLKEKVDAGAHFVVTQLFFRAETFLKFLKDCRAIGITCP
ILPGIFPLQGYHSLRQLVKLSKLEVPEEIMKVIEPIKDNDAAIRNYGVQQAVEMCKVLLN
SGEVPGLHFYTLNREVATTEVLRQLGLWAEDPRRPLPWTVSAHPKRKMEDVRPIFWSSRS
KSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSTKEDLLKMWGEELTREESV
YEVFTNYITAQPNQNGHKVMCLPWNDDPLAPETNMLKDELEKVNRRGILTINSQPNINGK
PSSDPIVGWGPPGGYVFQKAYLEFFTSNENAKALLKVLKKYEPRVNYHIVNMRGENITNA
PELQPNAVTWGIFPGREIVQPTVVDPVSFMSWKDEAFALWIEQWGKLYEDESPSRMIIQY
IHDNYFLVNLVDNDFPLNSCLWQVIDDMFELLSAPPEPLEENIH
>A0A7Y6R8R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas titanicae|TrEMBL
MSSHEHPLGISFEFFPPSTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTREVVR
AVGESGINTAPHLSCIGSEKAQLRDLLAQYREEGVESLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAITAF
GTDVVSRLCQRLLEGGAPGLHFYTLNQAAPVLRIVDNLAG
>A0A2H9RAJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon CG_4_9_14_0_8_um_filter_34_10|TrEMBL
MAIIYEVNPPKIPDNETPDDEIKSSIEKLMQRVSDISALCDGIHVTDSVLGTKRVSALTV
GRLLKKKHPDLQITISMRVRDKDMSLIKQLTQESIELKLDGILILKGDPSKENPTDSGLI
PSQVVKELNELGYGNKMNFFLSLPSNPNFEKIQKKIAASPKGFMTQVIHSAEQVQRISNK
LKPKGLRIIPCVLLPSEKNNNSAKFLELDWSNYKENPSNFIKQIHNIAGDVLVTSPNDFT
FAKETLKKI
>H0HSZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium alhagi CCNWXJ12-2|TrEMBL
MTSRQRDEHPDGIDRPLDPQPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
VFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAINPFAPPFDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRNYMQRVRDLGYTEQCFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLAIDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRRPWKREMRSDDQLVADRLDHILHDDIVETQSDLVK
TAH
>A0A367QYF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc minutum NIES-26|TrEMBL
MDDNHSHTVLNSFRRAAQAGEFLVTAEVAPPKGGNPQHMLQMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQNGIEPVCQIACRDRNRISLQGDLMGAHALGIRNILALTGDPVKA
GDHPEAKAVFDLEAVRLLQLIRKMNQGFDCNEKPLTDGALNLFVGAAVDPQCASWSGLQS
RFERKIEAGAQFFQSQLITDFERLEKFMDKIAASHKKPILAGIFLLKSAKNAQFINRCVP
GVNIPEHIIDRLAQAKDPLEEGMIIAAEQVKIARQLCQGVHMMAVKREDLIAPILDLAGV
TPVNLVGAK
>C7MZV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)|TrEMBL
MTTKSEVADSRRPRGLADLVGNISYEVMPFKSVERAVLADVPTSIPLTVTVTEAKGIDTT
LDFTERLMRHGYTVTPHLAARQFVDDNHVREVIDRLQTAGVNSVFIVGGDAPKPAGRFHS
AYMLLQAMQELGHPFSEVGIGGYPEGHANIPQSDIELALKQKAPLATRILTQICFDANTT
ANWAAGVAKSGIDLPIYVGMPGPVNRQKLVRISAGIGLGQSARFLQKQQNLLWRFLLPGG
YNPTKLARRLGSAVPKVRSNIRGLHIFTFNEIQKTEQWRRKLLASVSEKDKR
>A1A1F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a)|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVDEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREKRPDLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCESRVPEKLAVLLDKWGSDTALLKEAGIAY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A377I0Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parahaemolyticus|TrEMBL
MADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRAISQFFFDIDSYLRFRDRCVNV
GIDVEIVPGILPVTNFKQLQKMAKITNVKIPNWMYRMYDGLDDDPTTRNLVAASIAMDMV
RVLSKEGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A1Y3W7R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Barnesiella sp. An55|TrEMBL
MKVADLLKNTGSTGFSFEILPPLKGSSIEKSFKTIDTLREFDPLYINITTHRSEMVYKDT
ADGLFRRVSERSRPGTVAVAAAIKNKYQIPTVPHMICSGFTAHETEYALIDLNFLGICDL
LILRGDKAKHESRYTAMPGGYEHAIELEQQVNRFNEGYFIDGTRMDVVNSRPFSYGVAGY
PEKHDESPNPDEDMKWLKAKVDMGADYIVTQMFFDNSKFFDFVARCRAAGITVPIVPGLK
PISKASQLTLLPRVFHVDIPDGLVREVAKCKDDSQVKQVGIEWCTAQSLELKARGVPSIH
FYSLMAVDSVYRIAKQVY
>A0A1I5JPP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas composti|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMEVARQLATYNPDFFSCTYGAGGSTRDRTVNTVLQLD
GDVKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRVFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLDLKR
>A0A2R4TFJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lunaelactis|TrEMBL
MHSERFRALLDSVRYEVLPAKATLDKVLAHVPRDVVVTVTASPVKGLEPTLDLATRLSAH
GYSVVPHVPARLLRDDAHLADVVHRLREAGVDDVFVPAGDADPPAGPYEGALPLLRHLAE
LGSPFARVGITGYPERHPLIDDDITIQAMWDKHAHATYIVSNLCFDSRVLGEWVTRVRRR
DVTLPVHVGVAGPVERTKLLAMAAKIGVGESTRFLARHASWFVRFAAPGGYAPERLLRRS
APVLTAPSAAVAGLHLFTFNQIAETERWRRGMLERLDGC
>A4TA26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium gilvum (strain PYR-GCK)|TrEMBL
MTQPVTERDAGRDCPKRMTFGPCGGVHPDGQCEMRPGPCAFPDIVPWPTQAAPPPVTAPL
ILTDFSCTPFDPHDVAATANALAPSCDAVLVGEHQNRPDFPPTLMSRLLLEAGVTPWITL
SCRDRNRVVLEQELRGLSLLGVQTVLCVTGDGRAYDVRPDVTQTFDLDGPRLVELAASLG
MVAAVPETPTAPPVARRPLRLVQKQHAGAGIAVLNHVSSPSTVAEFMAAARAAGLVIPVL
AAVAVFTDDVSAAVLQGLPGLALDPAVVDRVLAAPDPVEAGIEAAVAEARALLAIDGVAG
VNVSGLASGAGTRVGAQIKAEVGARIRAERSVR
>A0A3R7ES00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanophagales archaeon|TrEMBL
SELKGLVTACNVTDNPQSFAAINSLAASYKIQEETGMECIYQLRCSDRNRMALCSDVMGA
GILGLKNVLTLTGDYVSLGDTPMAKPVYDLDSTTLTRMIHTLVHEGKDISGTEIPNPPKL
HVGAAAGPGMDPLEPELYKLKRKAIAGAEFFQTQVVYLPETIDRFFKGVKDLNIETPILV
GIFPAKTYGAAKFFDENVTGVDVPPDFLKNLEATKQIKDKEKRKEEVDRVNIEYFTGFLE
HLKGTPAVGCHIMAVGYPRIIPELKKVVE
>A0A522TDF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPDDFLQQVSERVLVSDGAMGTMLYARGVFINRSYDELNLSQPAVVKEIHLAYAHAGAEI
IETNTFGASPIALEKYGLREKAAAINRAGVALARECAGDAWVAGAIGPLGVYLEPLGKLS
FEEARAAFREQAAALAESGADLLMLETFGQVNELREAIFGARDACNLPIAAQITIDDEGR
ALDGTPAQEAARRMHDWGADIIGINCSGGPVGMLEALEAMARATTRPLIAQPNAGKPRNV
EGRNLYMVSPEYLADYARQFITAGAKIVGGCCGTTPEHIKWIRNYVRSTTPGRRRVQVNT
VAKPDAEERKVIPAAERSALGRRLAEGKFVTLVEILPPRGSDATKELESAAFFEQHGADA
INIPDGPRANARMSNQALALMLRSRLQIEPVLHYCCRDRNVISMQSDLLGGYALGLRNLI
LITGDPPKLGNYPDATAVFDVDAIGLANLVSNLNRGLDLGGNAVGGQTSFLIGVGANPGA
LNYEEELRRYRFKVEAGADYIVTQPVFDLEVMERFLHDTESHRRPLLAGIWPLTSARQAE
FMQNELHVQIPPAVLERMRAARTAEAAKAEGLAIAQEMVRALRGKIAGIQISVLGRNQAG
AVLLATAQENTAAA
>A0A7W0LH82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MVRPPFLESITERVLVCDGAMGTMLYGKGIFLNRSFDELNLTQPDLVAEVHQAYVRAGAD
IIETNTFGANRIKLGAFDLADRAHAINLQGARIARHAAREQAYVAGAIGPLGIRIEPWGK
TGVDEAEEQFRQQAAALLEGAVDLFILETFRDVNEVGAAIRAIRGLCELPIVAQMTTEED
GNTLDGVAPETFVPELEQFGANVVGVNCSVGPAAMLETIERMAEIATVKLAAQPNAGRPR
EVEGRNIYLCSPEYMASYARRFITHGVNLVGGCCGTTPDHIRHIKMAVRALAPAGKARER
QAGTRAVLPQVQVVARADKSRMAAALANGTFVVAVELVPPRGYRAEPLVEQARELRTSGV
DLANIPDGPRASARMSALSASVIVQQQAGIEAVLHYACRDRTLLGMQSDLLGAHSMGIRN
VLLITGDPPNAGDYPDATAVFDVDSIGLTNVVTRLNHGLDIGGQAIGAPTAFHIGVAANP
GALNLEEEVRRFEYKVKAGAEFAITQPVFDVRALVEFLERIAHVRIPVLAAITPLESLRH
TEFLANEVPGLRVPERVVERMRVAEADGRAAAEGMTIACEIATEVHPHVQGVQISTAAGA
LQSSLGVMRALTECSR
>A0A7I0KIE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae|TrEMBL
MNYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A3N5XA04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MMSKFLERLKQNVLVGDGAMGTLLMQELGPGHRCVEEANLSHPDAVLAAHLQYIAAGANL
IETNTFGANRGKLQDFNLDSKVEELNSRAAKIAREARDVAGKDVIIAGSIGPAGFAFDFT
SREDRGLAEDHYKEQAEVLEQRGVELFIIETFPSPSELRTAVQAVRSVSSLPIIAQLTFA
AADFDAGGDFEDIDLHRALESFQGISDLPVEVLGLNCGMGPREALRLLESIPLSPRYYIS
IYPNAGVPGRRGGRFVYPNSSPEYFASFALEAVRLGARIVGGCCGTRPEHISAMAEAIRT
ANPVERKSAPTATVSMAEPVEKPIASTSLIAQKFQQRKFVVSVQIDPPKGPETARLMEAI
EVFKQSGVVDAVDVNSNPMARLHMDSLWMSALVEQAGLPAIPHITPRDATIMGLQANLLG
AYAAGIRNLLVITGDPSQLGGEAGGMDVYQTDSIGLVKLITELNRGRDATGNPIGNSTDF
LVGVAVNPAAADVNAEVARFQKKVEAGARFAMTQVFFEWECWHRFLDALGGPSPIPVLAA
VWPLTSYRLALRLHHEVPGIIVPDQVLSRLEKAGKDARCVGFELARNILDNARREVDGAY
VIAPFKDPAAALEVLC
>A0A8I0M8D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. ENS10|TrEMBL
MRNENAPFDIKIHADGPSFALEVTGKDIGQIEAAKSSIASGTPINIAFLGNEDHSQRVNA
ARVIRVCGFEPVPIISSRRLHSEADRDTLIGGLIREAAPERFIFVGGDPAYPAGPFEDSL
ALLRSDVIRRHSIRHAGIVAYPEGHPKIAAEKLWESLKWKVGFLADAGCSVEITTQFGFD
ADAIVQWLERLRKEGINSPVRIGVPGPAAVGKLLRYAKQFGVITSASIARRYGLSLANNF
HRVGPERFWRRLGAGLIGRDLGPVHYHLYPFGGIEDGVKWLSHALEQPSTTD
>A0A2V8GHA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPLPDFRTELDKRVLVCDGAMGTMLYAKGIFLNRSFDQLNLTQPDLVAEVHQAYVRAGAD
VLETNTFGANRIKLGAFGLADRVQTINVQGARIARHAAREQAYVAGAIGPLGIRIEPYGK
TGVDEAEEYFREQARALVEGGVDLFVLETFRDVNEIGAAIRAVRSVGDLPIVAQMTTEED
GNNLDGVAPETFVPELEALGADVVGLNCSVGPAAMLETIERMARIAHVKLSAQPNAGRPR
EIEGRNIYLCSPEYMASYARRFIANGVRFVGGCCGTTPDHIKAIARAVEGVAPRPLPADS
WLSSRQPPAAGRQHRMANALARGTFVVSVELIPPRGFHAETIVEQARQLKIHGVDLVNIP
DGPRASARMSALSAAVLVQQQAGVETVLCFACRDRNLLGMQSDLIGAHAMGVRNLLLVTG
DPPKLGDYPDATAVYDVDSIGLTHVVARLNRAMDVGGEPLGQPTAFHIGVAANPGAMNLE
EELRRFAYKVEAGAEYAVTQPVFDVAELRAFLDRVRDHRIPVIAGVMPLAGVRHAEFMAN
EVPGVRVPETVLDRMRRADAAGRAAEEGLAIAREIAAQVRPLVQGVHISTAPKAIEAALG
VVEAVGA
>A0A2V9ZRL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSSDFLKRLAAGPILCDGAMGTLLYAKGFFINRCYDELNLSQPDLIRSVHQEYLQAGAEV
IETNTFGANSFRLARHGFGDRVHDINLAGASLARQIVTRKETDQTFFVAGSVGPLGVRIE
PLGKTSLEEARAAFRDQIAALVEGGVDVIFFETFTSLEEIHQAILAAREVDSAIPVVAMV
TIDEEGNCLDGSSPEAFGARLTEWGADVVGCNCSVGPAVMLEAIERVRRVTALPLVAQPN
AGPPQSVEGRNIYLCSPEYMASYARKLVAAGAQVVGGCCGTTPEHIRSMKAALRVGSAKG
TGFQVVTEAAKKVEIVVPPLEQRSRLGAKIASGEFVTMVEIVPPKGIDATKEIEGARYLK
SLGIDVINIPDSPRASARMSNQALSILIQQQVGVETILHYTCRDRNVLSIQSDLLGAAAV
GLKNILCVTGDPPKLGNYPDATAVFDVDSIGLVNIVHNLNRGLDIGANAIGGKNGTGFVV
GVGANPGVLNLDEEVRRFEYKVEAGAELAITQPVFDVTLLEVFLRRIEHCRIPVIAGIWP
LVSLRNAEFMKNELRVSVPDSIMKRMAAAANADAARAEGVAIAREMLLAVHEVVQGVQLS
APQSRYSSAVEVLQALEDGPKANVQVGS
>A0A8E2AF00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella multocida subsp. multocida|TrEMBL
MSYAKEIDTLNQHIADLNGKINVSFEFFPPKNEKMESILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLEAAPHLTGIDATPEELIEIAKDYWNSGIRRIVALCGDEP
KGYAKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLVKMAAITNVKIPAWLAKNYEGL
DDDPTTRNLVAASVAMDMVRVLSREGVNDFHFYTLNRSELTYAICHTLGIRPSSE
>A0A2V9K4B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MREPFLQKLEKRAVVCDGAMGTMLYSKGISLNRCFEELNVSLPQLVKEVHLGYVKAGAEV
IETNTFGANRFRLEKFNLANKVREINLAGARVAREVAGDDLHVAGSVGPLGVRIEPLGST
SLEEAREAFREQIAALAEGGVDLLVVETMMDPNEAHQALLAARDVCALPVVVQMTIQDDG
ISPVGTRPEDFARQFDGWGADVIGLNCSVGPAAIQEAIERMAAVTTKKLSAQPNAGLPRT
VQGRNIYLCSPEYMASYARRFVQAGVRLIGGCCGTTPEHIRAIKAAVRSVNPQPARAAVE
APRRQVRVMEPTVADKRSRLGAKLARKDFPLLVEIVPPKGCDPTKEIEGAQYLLERGVDA
VNIPDGSGATARMSALTLSAILQQRVGIEVLLHYSSRDRNVPSIQSDCLGAHALGLRNVL
ALTRDTSQYSTVLESEQFEVDAIGLVNILNQLNRGLDVGGNPLGTQTGFLIGASLNHSAL
NPEEEIRRFAYKVEAGANFALTAPVFDVERLALFLRRVEEAGCATIPILASIWPLTSFRN
AEFMNNEVPGVSVSQAIMERMRKADTGERARAEGVRIAQETLAEVRDLVQGVQISPPFGR
YATAVEVAQALGERAVARKDL
>A0A7G3F5G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp|TrEMBL
MKRISFEFFPPKTDEGRTKLLTTQQKLLAKKPAFFSCTFGAGGSTRDNTREMVGKLREQH
ADTAPHLSCIGQSREEILELVRGYRDSGVRRIVALRGDLPSGMGYAQSEVKYADDLVRLI
REETGDHFTLEVAAYPEMHPQARSFEDDIAHFKRKIDAGANSGLTQYFYNADAYGYYMDA
LRRTGCDAPVYPGIMPILNVANLIRFSGVCGADIPRWLRSKLDDIKDDEQAVKAFGEEVV
TRLCERLLAMGAPGLHFYTMNQAQASLRILDNLGL
>A0A2V7WFE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MQDFIQAIADEHIYLFDGAMGTMLYAKGVFINKCYDELNLRSPEIVLEVHKQYVRAGAEV
LETNTYGANRVKLRTFGIEDDLRDINLRAVELARKAAGDSVYVAGAIGPLGIRIEPYGPT
ALEEAREFFREQATALRDGGVDLFILETMSNIAEIEQGLLAIREICTLPIIAQMTIGNDG
LTIYGDTPRTIAERLDRAGADVIGLNCSVGPDVMLDAVEEISSVTAKKISCQPNAGLPRE
VGGRQMYMASPDYMAKYAKRLIHKGVKFLGGCCGTTPEHIKMMADAVRPLSPRRTLVIIE
RDAGGDKPAGVEPAALETRSNWGHKIAHGEFVTTIEIVPPKGPNPEAMIKSVQSIKDAGV
NAVNVPDGPRAQNRMGAIAVAVLLQQRVGIETVLHYCCRDRNLLGMHSDLLGCSALGLRN
MLLITGDPPKMGPYPDATAVFDIDAIGLTNMVSLMNRGLDLGGNPFGEGTKFTIGVGVNP
GHLDLDYELRRLEWKVKAGAEYAITQPVFDVVVLEKFLKRIEQMRLPIVPGIWPLLSYRN
AQFMNNEVPGVSVPDEVMERMRVASEKSKEHGMREGVTIARETLARVRGQVAGVQVSAPL
GRVDLALQVFDGLVEKRVSA
>A0A084U9N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor basaltis|TrEMBL
MAQHAKPLDPEHRAPLKVSFEFFPPKSEEMERRLWDTVQKLVPLRPHFVSVTYGAGGSTR
ERTSRAIERILDETPLTPAAHLTCVDASREEVDAVIRDFLSMGVKRFVSLRGDPAAGIGS
AYEPHPDGYANGAELAGALARLGAEDISVSAYPEKHPESADWDADIDMLKRKVDNGATRA
ITQFFFDNDLFEAYLERVRAAGIQIPVVPGILPVHNFTQMTRFAGQCGASVPNWLADRFA
GLDKDPVTHQLVAAAVAAEQVLDLVQRGVQDFHFYTMNRADLPFAICHLLGIRAEAQPAA
A
>A0A2V9MQL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIRDFLKRESPCFSFEFFPPKEEAGFQSLFETVKLLKQLDPTFVSVTYGAGGSTRRKTI
DLVTRIKHSLGVESMAHLTCVAASRQEVQQVLEELVANRMENVLALRGDPPKGQAAFLPD
PRYANELVHFIRSHYDLCIGVASYPEKHPECASLEQDLINLKRKVDAGADFLITQLFFDN
RDFFSFVERARKAGINLPIIPGIMPILSVPQIKRFTEMCGAKIPGELLQRIESVQNDPAE
VERCGVEYATVQCHELLEERAPGIHFYTLNRSKATWEIFKNLKS
>A0A2V9QDG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
VRRVGIHYALDQCHDLLDNDVAGIHFYTLNRSDATRVIFDSLGIPRHRGAEASSV
>A0A4Q3I4L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacteraceae bacterium|TrEMBL
METPDFSIEFFPPKTPEGAEKLRVTRAKLAELQPKYFSVTFGAGGSTQQGTLQTVQEIQA
AGHEAAPHLSCVGATRESIRAVLKQYQDSGIRRIVALRGDLPSGYGGAGELRYASDLVEF
IRQETGDWFRIEVAAYPEMHPQARSPQDDLQAFARKVSAGADAAITQYFYNADAYFSFVD
NVRKLGVTVPIVAGIMPITNYMQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCEKLLAGGAPGLHFYSMNQAVPTTAIWQRLRP
>A0A1B1NEX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serinicoccus hydrothermalis|TrEMBL
MEARLTGVETTVGSLETKIERRWTCCGADRSPPQVVRCRRRFPDPRGLLGNWAAMSTTQT
RISVELVPRSPESVRAEMAQVAERLPVVDTINIPDLLKFDLRSWQATEVARESTTRQDGA
AYRTIPHIRAADVDPDAPLPMAQEARRTGELLVVSGDDADYFHSSTYPVDAVDVIRRVRA
ELPEVTIYAGLDPYRQAMTTEMRYLDRKLAAGASGVFTQPFFDTHLMSAWAAVLPRDVPV
WWGATSVTTSGAMGYWRRRNRVVFPDGFDSGMPWQRDFARRVVDFARERGHHAYLMPVRA
PLLDYLGGVLDA
>A0A1F9CZW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_48_10|TrEMBL
MSFKEQLESGKFVVVAELQPPKGNNLSELYEYAELLKGRVDAINVPDLQNSIMRLGSLSV
CTLLKARGLEAIYNLSCSDRNRLALQSELLNASALGLKNILILQGDPPSIGDHFEARAVF
DLDVMGLLSATKRLQEGYDLVGNDLQGKPQFCVGTLINAAAKGHALDLEVMDMEKKIRLG
VEFFLTHSIYDVSLFEPFIKKVAHFKVPIIAGITLLKSVGMARYVNKHVEGASIPESIID
QLMKASDKQKASIEIAGGLIKALKPLCQGVQLIPIGWEKQIPALLDHVGL
>V2XY75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moniliophthora roreri (strain MCA 2997)|TrEMBL
MKITKKIEQCEKANKVWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTAEMVKTCQGMIGIETCMHLTCTNMPKEKVDIALREAKISGCRNVLALRGDPPMGKDD
WEAVEGGFVHGIDLVKHIRREYGDYFDIAVAGFPQHMLLPKEELDQEIQWLKEKIEAGVN
FIFTQMFYDVNIFIDWAKAIRDAGITIPIVPGIAPIQTWNGFMRATSLAKTVIPQHLMDA
LEPHKNDDEKVRAIGTKLVAEMCRTILNANLGIRGLHFYTMNLEKGTKMLLEELNLVPRV
ETLKPLPWRQSLTPSRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGEPTSFAEVADLFARFCSGTLPALPWSDQAPAGETSVISQQLA
RMNTLGFLTINSQPAVNGAKSDDKVFGWGPSNGYVYQKAYLEFFVQPALLSILLSHIERD
SNITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAYELGQQ
WAKIYDADSPSRKIISDLMDSCYLVNVVHNDFHDRDAIFRPFFKAGEEYLASSKGKTPMI
NGDAH
>A0A1V5YJQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium ADurb.Bin180|TrEMBL
MKVSSNLEKILASGQFAATGELGPPKSAEAEAIKRKAALLKGLVDAVNITDNQTAIVRMS
SIAVGIMLLQEGIEPTIQMTCRDRNRLAIQADLLGASALGIKNLLCLTGDHQKFGNHPTA
RGVYDLDSIQLVALVKALRDEKKFANGEAIETVEPRFFIGAAENPFADPFDYRPYRLAKK
VAAGADFIQTQLIYNVPKFKEFMKRVVDLGIHEKCFILAGVGPIKSIGMARYMQNSVPGM
DVPEDVIARLKGVPKEQVRKEGIKQCADIIQEMREIPGVRGVHVMAIEWEEAVQEILELA
GLLPRPRL
>A0A5B8DJY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methylopumilus rimovensis|TrEMBL
MAKKVSYSFEFFPPNTPEGIKNLADTRQQLSAFKPEFYSVTFGAGGSTRDRTLETVLEIK
NEGFNAVPHISGISSTKIEIKTLLNQYQQHGIKHLVALRGDVPQGEVPSGEFKHANELVS
FIRQETNDYFHIEVAAYPEYHPEATSAQIDIQNFKNKVAAGANSAITQFFFNADAYFRFM
DECLIADIDVPIIPGVMPIYNIKQLARFASNCGAEIPRWLRIKLESYGDDLPSLRSFGVD
VISELCETLVSWDVPSLHFYTLNQAGIISRIIQNIEGN
>A0A3N5M2U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSLGATGNPNPEANKNGLLAGSNLEKVLRAGHFAVTAELGPPQSADHLVIRNKARHLRDC
CDGVNLTDNQTAIVRMSSIAAGAILVQEGLEPIIQMVCRDRNRLAMQSDLMGAYALGIRN
VLCLTGDHQSFGNHPTAKNVFDVDSCQLVKMVSGMRDQRVFQCGEAIKGQEPRFFVGAAE
SPFAAPVEFRPYRLGKKVKAGANFIQTQLVYDVPAFETFMEKVRTLGIHEQTSILVGVGP
LKSPAMAKYMKESVPGILVPDELIQRMTKAGASWAGKKADEMSKEEKKARSEAWKAEGIK
ICIELIHKVRAVPGVAGIHIMAIEWEEAVRPVVEGAGLLPRPNMHEPPRTDTD
>G9QUP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. 10_1_50|TrEMBL
MLKEKFLNKEKGLVLYGLTPPKAEFEEAKLREISERWTGRINDIKADGLVLYEVQDESER
NNSERTFEFSGTLSPEIYYKKYLNVATPSIFYHVASGYGEDEFRAALKAQSSNLNVLVGA
TSSTQKVRLNLARAYEIASEFKELAVGGVCIAERHGKKGDEPQRMREKIAAGAKFFISQA
IFDAQLARKFLEDCAAAKISEPIFLTFSTAGNAKTLEFIKWLGVSVPSSVEERLNLSSDY
LASSCEIIKEIWCELKKFGDENGLNLSINIESVMAKRAEIEASLELTKSIRELV
>A0A4Z0BJN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramlibacter rhizophilus|TrEMBL
MPAGHPEEKAVLPISLEFFPPKTPEGAAKLRAARQQLYATRPQFCSVTFGAGGSTQEGTL
SAVTEIMAEGVPAAPHLSCIGQTRESIRERLAAYAAAGVDRIVALRGDLPSGYGLGGEFR
YASDLVAFIRAQTSRQFHIEVAAYPEFHPQARSPQADLQAFVAKVEAGADSGITQYFFNA
DAYFRFRDELDRLGVAVPVVPGIMPITSSSQLMRFSDSCGAEIPRWIRLRLQAFGDDTAS
IKAFGLEVVSRLCEQLARGGAPGLHFYTMNQAQATLALCQALGR
>A0A2V8BYZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
ARVSALSLAVLIEQQAGVETLLHYSCRDRNLLGIQSDLLGAHAMGLRNLLLITGDPVRIG
DYPDATSVFDVDSIGLTNVVARLNRGCDIGGQAIGAPTAFHIGVALNPTTTDLDQELRRF
EYKVEAGAEFVVTRPIFDLRAFELLRKRIQSARLPVIGGVVPLESARHAEFMANEVPGIR
VPDELLARMRRAEDAESAAREGVAIAREIAMELQGSVQGLQIATASGDTDAALAILDGLH
>A0A4R8WUZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. MDT1-3|TrEMBL
MQKTSDPACSGRIPFSFELYPPKTDADASALSTTIEHLAAVGPDFLSVTYGANGSSRRSS
LDVLSRILRTTNVEAMAHLTCVGSTHDEANRLIREFLDAGVHSFLALRGDPPAGTKEGEA
FLGDFGSAAELVQLIHRVQAEKSPYRESIIPGIPAARAVTPGREKVRIAVAAFPNGHPRS
RSSAQDIDTLLAKQAAGANLGITQLFFHADHYLSFAQRAREAGVLFPILPGIMPVTSPAR
LRRIIELSGEQLPSDLSIRLEVEPTKEGQREIGIQHAVDLAGRVIAGGAPGLHLYAFNEH
ETVLEVLAACGLLTSPVAAPA
>A0A2P7P5F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. ND22Bw|TrEMBL
MSAQEHPLGISFEFFPPNTEAGRDKLMQTRDALATRGPRFFSVTYGAGGSTQHRTTDTVR
MVRESGFTTAPHLSCIGSEKAALRDLLNQYREEGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFNIAVAAYPETHPQAPNADRDVENFARKMKAGANLAITQYFFNADAYF
RFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSESIAAF
GEDVISRLSQRLLDGGAPGLHFYTLNQAEPTLRVVDNICG
>D9T6B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / BCRC 12538 / CBS 129.76 / JCM 10878 / NBRC 16125 / NRRL B-16091 / INA 9442)|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTPAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWIAHPEGVRYAEGLVRLVRDSGDFSVGVAAFPYKHPRSPDVDSDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFEQVADDPEAVRRLGVEQASEMCEKLLDEGVPGIHFITLNRSTATREVWQRLR
AAARV
>A0A6H3NP56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira levettii|TrEMBL
MIQILLEVVPRDLSVVIQEVDFVKNKFKQITGINIPDLLRFENRSWDVASVVRPVFPNVI
PHIRAIDFDLDNCEPLVKTLQELQIASVVVIKGDPPTDMSKQVYPTTSVKLIKKLKKEIQ
HLKVYAAIDQYRVGIKDEFDYIEMKKDAGVDGFLTQPFFDMRLVDIFSEKLRGTEVYIGV
SPVVTEKSQSYWESRNRAYFPKEFRPSLEWNVKFAKDVLTYCSEKGMNAYLMPIRINLEE
YLQQIFD
>A0A1M4WW20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforamulus putei DSM 12395|TrEMBL
MKISTLFQQKKPVISFEIFPPKINTPVETIYETLEDLTKLNPDFISVTYGAGGSSRDRTK
EIASRIKNQYKVEALAHLTCVGHSSSEIDLVLKGLQEENIENVLALRGDPPADNPDYDFS
RCDFQFASDLVKYIKNLSDTCIAAAAYPEGHAHCNRLSEDLNHLKYKVDQGVDFLITQLF
FDNRIFYNFIENARRIGIHCPVMAGIMPVLNAKQIKRIIALCGASMPAKLLMMVDKYGDN
NEEMEKAGIEFASQQVRDLIENGVEGIHLYTMNKPRQITEILKNVGIVI
>A0A7G7SFS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. SS|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKTYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFDAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQASDALSDLRHFKAKVDAGADGAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQALGDDADAIREFGADLV
AALCERLLAGGAPSLHFYTLNLAKPTVSVLSRLA
>A0A426UA94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. RP5T|TrEMBL
MNRAPGAPTVREVLADGVPFFSFEFFPPRTEQGTRTLWDAVRRIEALSPAFVSVTYGAGG
SSRDRTVAVTRRIAAETTLRPVAHLTAVGHSVAELRHILGQYADAGVREVLALRGDPPGD
PNAPWRPHPEGFRHACELVHLVKESGDFGVGVAAFPEMHPRSADWDSDIRHFVAKCRAGA
DYAITQMFFHVEDYLRLRDRVEASGCGTPIIPEIMPATDVRQIRRFAALSGAAFPEDLAR
HLDAARDRPAEGRRIGVDYATAMARRLLAEGAPGLHCITLNRPSAALEIHQRLRTAVGAA
RS
>A0A4R8R8Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum trifolii|TrEMBL
MHIKSMLDETRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREHEK
WEATDDGFQYARDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGASF
IVTQMFYDGDNFVRWVGKVRERGITVPIIPGIMPIATYASFLRRAKHMNCKVPDEWMAAL
EPVKNDDVAVREIGKGLVADMCRKILAAGIHHLHFYTMNLAQATRMVLEELNWMPSNERP
LKHALPWKQSLGLGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPRSIKDIANIFVRYLETEIDTLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSSHPVHGWGPPNGYVYQKAYLELLVHPDMYPEIISRIEKNP
DMTYYATTKNGPLKYNAAHDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGTDW
AHCFEAGTPSRVLLDRIMNEWYLVNIVNNDFHQKTALFDLLDGLSIKEYNDIPSEPQVQT
NGQANGVSKEQASELSNGNVAPIPA
>A0A1H4VQQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 2231.1|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLAYAAELVRLIKESGDFCVGVAAFPEMHPRSSQWDTDVQHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPKLSNARF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A014D288|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_1|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A1Y2HPZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catenaria anguillulae PL171|TrEMBL
MKIIDKLRRAEAEDRITWSFEYFPPKTDQGIQNLYDRLDRMHALGPTFIDVTWAAGGSTA
DTTLDVCEYAQKVAGLEVCMHLTCTNMPKQMIDDALAKAREIGIQNILALRGDPPRGQER
WTACEGGLSYAVDLVKYIRQTHGDYFGIAVAGYPEGHLENPDREDDLRRLKEKVDAGADY
IITQMFYDCDMFVEWVAACRRIGITCPILPGIMPIQTYGGFQRMTSLSKTAVPQHIHDAL
EPIKDDDAQVKEYGIRLAMDMCTQLRQRAGISCFHMYTMNLERSVRLILEGLEWVAPREV
VRPLPWTPSLAKKRVGESVRPIHWRNRPRSYISRTETWDEYSNGRWGDAASPAYGELDGY
NTRLKQTKEEALAIWGKPSTPAQVRRVFVDFCQGAIRALPWSDFPLSGESNLIRTELAGA
NARGFLTINSQPAVNGKPSSDKLVGWGPRNGFVYQKAYIEAFVPRHVLDALEQELRECDP
DAIVQYHAVNRDGSDLRSNHAADSPNAVTWGIFPGCEVKQPTVVDLTSFLAWKDEAFLLW
DQWVNVVPEGENALLQEMASEWYLVTLVHNDFHEPSSALFDVLKRVARKVEGIPEEADAE
EVLRIVAEAKKGEEVPAVSSLVDEKQSRATTTAAAAEGNVSEARNREAIAAL
>A0A7U5HSE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis|TrEMBL
MGLLQDLEERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIVQTN
TYGANFIKLSRYGLEDDTKRINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIAGLGADITGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEGGRLVY
DTDDAYFRESAIQFRTQGARIIGGCCGTTPNHIRAMADAVHGLSPVTDKEVKIRREEEVI
SVRDERTDPGLDEIAAQKRSIIVELDPPKKLNFGKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMAQAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A6A6NFM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hevea brasiliensis|TrEMBL
MATTLALLSLVIQVLKAILGFLLCPILLHYPQKIISLCSSAIFRSEAHPDMIGSDGVATP
ENYQKDLEYFKRKIPAEVTAALEPIKDNEEAVRAYGIHLGTEVCKKILAHGIKTLHLYTL
NMEKSALAILMNLGLIDESKITRSLPWRRPTNVFVQRKMFVQYFGLIVPRATYQEP
>A0A7Y4MGI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. 147(2020)|TrEMBL
MADDPGSLPLRVEIIPAPGIVEALREHLPAPAVVTITCLAHHGAEETIDLAVRLADLGYR
AVPHLAARSLKSRGQLAGFLTRLQTAGVSDIFVIAGDGEEAAGSYAWSGALMADIASLGG
GWFSLGTAAYPEGRPGTSSSELTDLLLAKQDLCSWAVTQLCFSGPVLSTYLTELRAAGVW
LPVWAGVPGAVRRTRLISLAARIGVGPSLRFAQRSLTGAGGGSLVRSVLAPSSYDPAPLI
RSVVDSGWFAGLHVYSFNDVQSVARTFGADA
>A0A151I7P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyphomyrmex costatus|TrEMBL
MRNLIFEKDICEKNDADGNNNPSTSYFYTENSHKTVVDLRQLLKDKINKNEIFCSFEIVS
TKKPSTFYRRLLLDMEEYSPLFYALTWHNEAASDNDSYLPLDLVENFPLNTLLHLAAKDS
LSENGDFEHAADLVAFIRQRFGDTFCVCVAGYPQMHPESASKEFDLHYLKAKVEAGADFI
ITQICFESRVLIDFVKDCREIGIQIPILPGILAPTNHGCLEKMIDICRLDVPIDIKDDLA
RMKDDDQAARKYSVDLITRIITDVIRSGATCGFHLFTLNRLSLIAEICKHIESVKAENLA
EKIF
>A0A8J4WEG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora kernoviae 00238/432|TrEMBL
MKVIDKINASIERQEVFYSFEFFPPKTPAGVENLYARMDRMAALEPLFCDMTWGAGGSSA
QLTTELSANAQKLSGLEMLMHMTCTNMAAGDIKKALDQAKEAGIQNILALRGDPVRGATS
FDECDKGFSHAVDLVRYMREEYGDHFCIGVAGYPEGHTESEDKAADIKYLKEKVDAGADF
IITQLFYDVKVFVEFVKECRAVGITCPIIPGIMPIQNYGGFERMTSFCNTYVPEEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSSRAAESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELAESH
FAATNTSTPKERRGMWGDAPATKHDVRQTFVQYVRGEISSLPWCDAALHAETSTVQHELA
SANAAGFLTINSQPRVNGALSDDPLFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
SSVQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYENGSQSAKLLREIHDTYFLVSIVDNDFGPDKGTYVMTCGQDKTVKLWNPHRSGVE
NDNKALLIKSYEGRHGYDVQDVAITHDNAKFASCGRDRDVFMWDVPTAKVIRKFEGHKQS
VNCVRYNADSSVLLSGSYDKTIRAWDIRARNAYTPIQVLDDFKDSVTSMVVTDHEIIAGC
VDGVVRTFDLRAGQISREHIDEPVVSVAHSPDARFVLAGCLDGSIRVIEKANGTEVKSYR
GHIVQDYKLDCGFSNDGAFVLSGSEDGKIYWWDLLDATNAHSISAHNKPVRALACHPESS
MFVTGCIDGSAKIWSHN
>R5FX84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:81|TrEMBL
MNLREYLKTTNLITDGAFGTYFAAKYQTQDIPELANITAPEKVKKIHEEYLNAGAKFIRT
NTFASNKETLQEDFAEVEKNIQAAVEIARDAVNGRDAWIAGDIGPIPVNGTEDAAAAADE
YYQIAKTFAERGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGRPGDKFLIAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADIFGGCCGTTPEFIREMSSWDGILNKIVLDTETDNGEQTGH
VQRHGFIYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLSVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTEEDAARLRRIKEETGAKILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>A0A5D4N1D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis|TrEMBL
MGLLEDLQKQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGADIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVRIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETGLPIMLNVSMHEQGVLQDGTP
LSEALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTRAKEFIS
VQHERTEPGLNEIAAEKRSIIVELDPPKKLSFDKFLSAASELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGEDKEKQKAEGLAIAHSLLDAACELFNGIYLITPFLRSDLTAELTTYIQ
QKDEQRQNIYLR
>A0A1Q8AZ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_20CM_2_65_9|TrEMBL
MQSFREAIEDRVLVCDGAMGTMLYAKGVFINKSFDALNVAQPDLVAEVHQEYVRAGADII
ETNTFGANRIKLGSFGLADKLHAINEQGAKIARHAADDRAYVAGAIGPLGIRIEPWGKTG
VDEAREYFREQAQALLDGGVDLFILETFRDLNEIGAAIDAVRSISDLPIVAQMTTEEDGN
TLDGTPPERFAPELEKRGATIVGVNCAVGPAPMLDTIERIAAVTPLKLSAQPNAGKPRDV
EGRNIYLCSPEYMASYARRFILHNVRVVGGCCGTTPDHIRQIKTAVRSLAPGLVRGASRA
EPPAESGGAKAGGVSRATVSAAIASPPIAREHKSRLAHAMAKGTFVVAVELLPPRGYRAD
DVIERARQLKIQGVDAVNIPDGLRGGARVSALSLAVLIEQQAGIETLLHYSCRDRNLLGI
QSDLLGAHAMGLRNLMLITGDPGRVGDYPDATAVFDVDSIGLTNVVSRLNRGCDVGGQAI
GAPTGFHIGVSVNPAASNLDQELRRFEYKVEAGAEFIVTRPIFDVAAFERFLTRIEFARL
PVVAGLFPFESARNAEFMANEVPGVRVPDAMLERMRRAEGAETAAREGIAIAREIAASLR
SAVQGVQIATASGDIDAALAVLDGLR
>A0A1B8PFC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus haemolyticus|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPE
>A0A4R7D0Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium paludis|TrEMBL
MKIVDHIKNAKGNPLFSFELLPPAKGQGIKSIFSTMDELMEFKPPFIDVTYHREDYLYKQ
HDNGLLERVAYRKRPGTVAICAAIMSKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDPDFIPTPGGHAFATDLLQQVVDMNQGQYLHEDIESSAKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVTKCRENDIHVPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSDAVDSCKTNADVRQVGEEWLVNQCKELIKFGAPVLH
FYTMSNPGPTKKIVERLA
>A0A255T3R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. P3-122|TrEMBL
MRVTELINSTDKDRKFSFEVLPPLKGNGTANLFSTIEKMRDYDPMFINITTHHSEYVYKE
LDNGHYERQRIRRRPGTVAIAAAIQQKYSIPVIPHVICSGATIEDIEYELIDMQFLGIDN
LLLLRGDKAKEDRMFTPTKGGHEHTTELIKQVNAFNNGIFADGTPIKHPCGIFHYGVAAY
PEKHEEAPNIDMDMQYLKMKQDLGAEYAITQLFYDNRKYFDFVRKAREMGITIPIIPGVK
PFAKLSQITVVPRTFHCDMPQELAAEAVKCKSDMEAKQLGIEWTANQCKELYEAGVEDIH
FYTVSAVDSVAEIVRRIL
>K2LHY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira profundimaris WP0211|TrEMBL
MMTVPEINAVRKHLKVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGTTRDR
THGSVTRIQGETGIPAAAHLTCVGHTKEEIDQIARSYWNEGIRSIVALRGDLPDAGDKYE
PTPGGYAYAVDLVAGLKEIADFDISVSAYPETHPDAPSSDFEIDYLKRKIDAGANRAITQ
FFFDNETYLRFRDKCVAAGIEAPIVPGILPVTNFASLLKFADMCGASVPQRLHWRFEGLD
EDPDTRRMVAFHEAISQVEGLISEGVTDFHFYTLNRAELTYAICHALGIRGTEQVAA
>A0A3R6F8I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLHQQGDKLGFSFEVLPPLKGNGTATLFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHTHATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDDDAKQLGIEWTTAQVQDLFEHGYKNVH
FFTVSAVDSVKQIAKILF
>G2Z082|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium branchiophilum (strain FL-15)|TrEMBL
MKVTDHITAAKGATLFSFEIVPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVN
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFIPTQGGNHYAADLVYQIKQLNQGNYLHGVADNDNKSDFCIGVAGY
PEKHLESPSLTTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEKAREMGITVPIIPGIK
PLAVHRHLQILPQIFRIDLPEELIQAVEQCKNNVAVRQVGIEWAIQQSIELKAAGVPLLH
YYSMGKSENIRQIASKVF
>A0A024RYS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypocrea jecorina (strain ATCC 56765 / BCRC 32924 / NRRL 11460 / Rut C-30)|TrEMBL
MDRITDKIAALPADAEYFSLEFFPPKTQMGFSNLRVRLQRMERALRPLFVNVTWGAGGST
AQKSLELAELCQRELGLTTCLHLTCTNMSQALIDQALDDARALGIRNILALRGDPPRAEY
RDADEPTEASEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPYL
VDKVQAGADFIMTQLFFDIEAYEKFETTLRNHPSGAFKTIPILPGLMPIQSYAMIKRTTK
LSHAKMPDAIMDRLNAVKGDDEKVKMVGVDILSELVEQIREIKSRTPGPKGFHFYTLNLE
KSVSFILERTKLIPDIPDEEEAIADESPAVAAVQRMIPKISVNGNVPPRAPSHTRTARRQ
SSVGSDPHNRVIVGRAATHPEWEASSTEAGIPAGSVNTRANTLAISEGEGALGREATWDD
FPNGRFGDARSPAYGEIDGYGVSLHMSVTQAVRLWGYPKVASDINDIFVRHIRGEISAIP
WSEEDLLPESSIIKDKLEALNRKGWWTVASQPAVNGLPSSDPTFGWGPASGFVFQKSFVE
FFLPSADWKILYDKLTSAEVEEVVCFYATNAKGDFVSSDYTGGSARAGGSESTNAVTWGV
FPGKEIVTPTIIEEVSFRAWSEEAFGIWAEWAKVYGRGSDSQKLLDGIREDYWLVNIIHH
DYVDTDALWRLLIE
>A0A2P8QKI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroococcidiopsis sp. CCALA 051|TrEMBL
MHNTTRLNSFRKAVKAREFLVTAEVAPPKGGDPSHMLQMAQALKGRVHAVNITDGSRAVV
RMSSFASSVILSQQGIEPICQVACRDRNRIGLEADLLGAHALGIHNILALTGDPVKAGDR
TDAKSVFDLESVRLLQLIGKMNQGLDCDDKPLTDGATDLFVGAAVDPQCKSWSGLQSRFE
RKLAAGAQFFQSQLITDFDRLEKFMTQIASGCNKPVLAGIFLLKSAKNAQFINRCVPGVN
IPEHIIDRLAQAKEPLAEGIKIAAEQVQIARQLCDGVHMMAVKREDLIPQILDLAGIPPV
VSYSLPSQVASSLR
>A0A7Z9I6M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterales bacterium|TrEMBL
MEYQSLLHKKLLDGNFVYTAETTPPDSADQEVILTKTKPLKYIADAVNLTDSPGAKVHMS
ALTAAIILAQNDIEPILQLTVRDRNRLALQGDLVGASALGVHNILCLSGDDPKIGDQPET
IAVNDIDSLTLVATADLMRRKGKFPSGRLIEPPPKFCIGGAEVPTEGKPNTEKILNKIKT
GINFFQTQYVFDKKILKEYMKVLDDVGILEKTFFIIGLGPFTSAKSAKWMNNNLFGVNVP
EKIIKRLEQSKDEKEESKKICLELIHHFKEINGVMGVHLMGHNKEEIIAEIIQESRKNNN
>A0A7W4W138|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides soli|TrEMBL
MRNRMTNRQTLSRLLELARYEVLPTASTEQKVLDHVPRDVTVTVTASPGKGLEATLDLAE
RLAGHGYAVVPHLAARMISGRTELAEISERLVGKQISRIFVPGGDADPAGDYPDALALLE
DLAALGRPFAHVGITGYPESHPTIDDDLTVQSMWDKRRYATHVVSNLTFDPGVIRDWVHR
MRRRGITMPLLLGVPGPVERTKLLAMATKIGVGESTRFLAKHKGTFARLAAPGGFTGESF
LEKCAPTLAEPTALVEGLHVFTFNQIAETEAWRQDLLGRLRG
>A0A0S7BEY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Longilinea arvoryzae|TrEMBL
MGLENPFLKLLESGKPILSDGAMGTMLHKRGIGFDVCFDELNLINPAVVGDIHREYIEAG
ANIIQTNTFGANRYKLEQHGLEDKLVEINAAGVELARRVVWASFKNVMIAGDVGPLGVRL
APFGRVLPEQARQAFAEQIAAMANAGVDLVIIETMTDLYEVREAIAASRQVAPYLPVIAS
MTFTRDDRTLLGDDPVKVARAMHGYGADVIGVNCSGGPNQLLRILKIMREAVPEAKFSVM
PNAGWPQQVGGRIMYPADPEYFGDYALSLWNAGATVLGGCCGTTPQHIAAMAHALENAAE
RVEIEREAAAVADHDEPQPTNAPPTQLAKKLAENSFVVTVEMDPPRGLSTHKLLAGASLL
AEAGADVIDVADSPMARMRMSPWAVCSLLQRRIGVETVLHFPTRGRNLLRVQGDLLAAHA
LDVRNVFVVMGDPTAIGDYPDAADNFDLVPSGLIKLIKQGFNAGVDHAGVDIGQPTSFFV
GCALNLHPDDPEHEIKNLRRKLRAGADFILTQPTYNPAKAHEFLERVRNEVGESMRPLLA
GILPLASGRHAAFLHAEVPGVLIPEEMRSRMNQAGDAGAREGIKIAIELAHALRADFNGI
YLMPAFNRFDYAAEIIETVKREIE
>A0A3B8N2S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacterium commune|TrEMBL
MKFRSNLERVLKSGYMAITCELAPPKHASLEPLKKKARVLKGYVDAANITDCQVAMVRLS
SLAGCLAIMLEGIEPILQMTCRDRNRIAMQSDLLGAWALGIRNLFCTTGDHPKFGNHPQA
KPVFDLDSVQLVAMVNQLKQGRFLNGQEIKGENPRFFIGATENPFADPSEYRVRRLAKKI
KAGAEFIQTQLVYDVTKFKQFMYIAHNEGLTEKAYILAGIVPPKSFRMIDYIKSHLPGSC
VPEDLVKRMREAKDPLEEGIKIAVELIEQIKEIPGVKGFHLMAIGWEEYLPEILKKTGFY
PRPFSQDLLPEDTKTFSLREQEKKHLEEEIKNLKEHLLRLESLITGKKEIKEEDSEKVSI
TIETPKEKTTAVVEDLTKTSPSSLAPAKEESLTGEKSRLKVLYRSLSERAKGLPEDLYRE
PASGRIREVVFGKGDKALKVGGAEALPFHSFEGSLGQPLRIAMEVLDVVPEDFPEVLAKY
FKDVWDDPGSWAKKCVEEYGAEAIAVYLLGIDPNYLNLGADHAKRVIEKVKKAVDVPLII
WGCDNAEKDTEVLREVAEVIKDDNILFGPIVEDNYRTLGAVALGYQLPVIAQSPIDVNIA
KQLNILLENLGVPLEKIIMDPSVGALGYGLEYTYSVMERIRLAALYSNDVKLQNPFICNV
GREVWKTKETSLPSDEFMGEAEMRGVMMEVITAVSLALAGGELFILRHPKSLELTKRVLN
LLWTSSEQKP
>A0A6L5B9Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apium graveolens|TrEMBL
MKVIDKIREISSSSSSNGDDKVVFSFEFFPPKTEEGVENLFERMERMVSHNPTFCDITWG
AGGSTADLTLEIANRMQNMVCVETMMHLTCTNMPVDKIDHALDSIKSNGIQNVLALRGDP
PHGQDKFVQIQGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDVIQSNGVATLESYQN
DLAYLKRKVDAGADVIVTQLFYDTDIFLKFVNDCRQIGITIPIVPGIMPINNYKGFIRMT
GFCKTKIPADVTAALESIKDNEEAVRAYGIHLGTEMCKRIMASGIKTLHLYTLNMEKSAL
AILMNLGLIEESKISRTLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWEQYPHGRW
GDSRNASYSALADHQFMKPRSRDKKLHEEWVVPLAKVEDINEIFNNYCLGKLRSCPWSEL
DGLQPETKIINEQLGNINLKGFLTINSQPAVNGAKSDSPSIGWGGPDGYIYQKAYVEFFC
STEKLNTLVEKCKGFPSLTYMAVNKEGSWISNIKQTDVNAVTWGVFPAKEVIQPTVVDPS
SFLVWKDEAFEVWSKGWAQLYSEDDASKNLLEEVKSSYYLVSLVDNDYIHSDLFAVFKDL
>A0A388Q2T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterales bacterium|TrEMBL
MNKDLNISFEFFPAKDEAGHENLWHSLEKLEQFSPKFVSVTFGAGGGERDKSDFLVKKIS
KKSNTPVAGHLTCVDMSKNEINSIALDWLNNGINKIVALRGDVRKKDSKYMPHKNGYENA
ADMVNGLKKLGNFHIAVAGYPEKHPDSENETKDLENLKNKVDQGADKIITQFFFNDEKFL
KFRDKAISLGIKIPIIPGILPIDNFEKIKNFSKKCGTSIPIWVEEEFAGLENDNEVQKIV
GASIACDLVKKLQLEGVNEFHFYTLNKYELSYAVCKRLIADKTKIKINQLKELNV
>A0A7Y7LR59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. SG517|TrEMBL
MSFEFFPTKTPEGAVKLRAVRQQLYARKPQFCSVTYGAGGSTHQGTFGAVQEILSEGVDA
ASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVGFIREET
GRDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDDVRKL
GLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVVTDLC
ARLQEGGAPALHFYTMNQSAATLAVLERLD
>A0A0C9RQX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wollemia nobilis|TrEMBL
MKVIEKIQNAEKEGKVVFSFEFFPPRTEEGIDNLFERMDRMVEHQPSFCDITWGAGGSTA
DLTLDIANKMQNMICVESMMHLTCTNMPVEKIDHALETIKANGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHIRLKYGDYFGVTVAGYPEAHPDMILSESGATEEAYKKDLAYLK
SKVDAGADLIITQLFYDTDIFLKFVNDCREIGIKCPIVPGIMPINNYKGFLRMTGFCKTK
IPSEITAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTVHMYTLNLEKSALAILANL
GLIDMTKIKRPLPWRPPANVQRTKETVRPIFWANRPRSYIARTIGWEQYPHGRWGDARSA
AYGAVNDYQFLRRRSRNKKIVEEWVVPLSSIKDVEEKFSNYCLGKLKSNPWSELDGLQPE
TVKINEKLAQLNLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSPEKLN
AVVEKAKQIPFLTYIAVNKKGETVSNVSPNDVNAVTWGVFPAKEVIQPTVVDPISFMVWK
DEAFQAWDNEWAILYPDEDSSKKILQEVQNSYYLVSLVDNDYIHGDIFSAFEEI
>A0A1V6LUM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceivirga radicis|TrEMBL
MKVTEHIANAKGETLFSFEIVPPVKGKNIQDLYDNIDPLMEFKPPFIDVTTSREEYVYIE
KNGLLEKKVTRMRPGTVGICASLQYKYNVDTVPHVLCGGFTKEETEYMLVDCQYLGIDNV
MALRGDAMKGEQYFSPCEGGHSYAKGLVEQIAALNQGKYLIDELKMEHTPNFCIGVAGYP
EKHLEAPSLQNDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVDAARAMGITIPIIPGIKP
LAVQKHLRLLPQVFWVNLPEDLIDAVEACPDNKAVRQVGIEWAIQQSKELKDAGVPVLHY
YSMGKSSNIKAIAAALF
>A0A2N1T4E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetae bacterium HGW-Spirochaetae-10|TrEMBL
MNKILLEVIPREVNTLLNEVSYVKNSYSQISGINIPDLLRFETRSWEAAVAVKSVFSNVI
PHIRAIDFDINNCDPIINFLRENQISSVVVIKGDPPADMSKKVFPTTSIKLIKKLKKEIP
SLKVYAAVDQYRAGIRDEFDYIEMKKDAGADGFLTQPFFDLRLIDIFTEKLHGTEVYIGI
SPVITEKSQSYWESRNRAYFPKDFKLTMDWNTSFAKDVIGYCKKNGLNTYLMPIRINIEE
YLGSLFGPDTTPSAGKVNVCK
>A0A3S5J896|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillales bacterium TMED33|TrEMBL
MTAPRVSFEFFPPKTPEAEAGLWKTVERLAPLNPEFVSVTCGADGSTRERTHQVIESILT
KTSLKPVPHLTCVGAPRSEIDSIADGYWDMGVRQIVALRGDPAGGAEAAYVPHPDGYAFA
PDLVQGLLERHPFELFVAAYPETHPQAGSVDADLENLQRKVDAGGHRAITQFFFDNEIFL
RFRDRVAAMQIDVELIPGILPVTNFNTLVRFAGACGASVPTALSMQFEGLDDDPTTRQLI
AAHAAVSQAEDLGREGVEDFHFYTLNRADLSFAVCHALGVRGCA
>A0A412NZK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF18-8LB|TrEMBL
MRVDEVFKQAASLGTVPVSFEMFPPKGELTLDTARKVAGSLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVNNILALRGDLPAGAT
EDDKPASEYAHARDLIPELVDAGFCVGAAAYPEGHIACEDLSLSVEYLKQKQDSGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMSKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVEYATRQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>M5CTF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia RA8|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQG
>A0A561DW16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. AG1028|TrEMBL
MSQKRPNVSFEFFPTKTDAGHEKLLNTARELAGYNPDFFSCTYGAGGSTRDRTLNTVMQL
DSEVKVPTAPHLSCVGDSKAELVELLNLYKSKGINRIVALRGDLPSGMGMSSGELRHAND
LVELIRAETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADCYF
YFVERVRKLGVDIPVIPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDTQSIQRF
GEEMITGLCERLIEGGAPGLHFYTLNQAAPSLAVWKNLQG
>B0MQG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] siraeum DSM 15702|TrEMBL
MKIKDLYTPGRTVFSLEVFPPNKNFPIETVYDAIEGLAAINPAYISVTYGAGGNRANRST
CEIASHIKKKYGIEAMAHLTCINSTRDDVDFMLDDFAANGIENILALRGDNKPDEEPKND
FPHASDLTAYIASKGNFDIAGACYPETHVDAESAEEDIKNLKIKVDAGASHLVSQLFFDN
SCYYDFEKRARAAGIDVPIAAGIMPVTNKKQIERMVTLCGASLPSKFVKMMQKYENDPEA
LRSAGIAYAIDQIVDLISNDVQGIHLYAMNNPAVASRIYNGIKDLL
>A0A0N1HTA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phialophora attinorum|TrEMBL
MIDERLPALIASVPPDQAYFSLEFFPPKTQAGFNNLQSRLSRMATALKPLYVTVTWGAGG
STSAKSLELAEVTQRQLGLPTVLHLTCTNMRRSMVDEALEACKELGIRNILALRGDPPRE
EYREESPPRNGSSSPKPDEFVWAIDLVKYIRKKHGDYFALGVAGYPEGHADESHPEAGKQ
SVEHDLPYLVDKLREKTAHIQDRRRQRSIYSDTDHPRLMPIQSYQIVKRITKLSHATLPK
DIADRIEKVKDDDNAVKRVGVDIMSELVEQIRALPQPEGLPRGLHFYTLNLEKSVAFILE
RCHLLPHLNEASPDEGSDSDVVQDNDYVLVSNDVAPPSQPRISRRRASSVNAQPTTVLSW
TAALLEAENRTGIPAADPNRKHSLLISEGQGSLGREATWDDFPNGRWGPAHSPAYGEIDG
YGPSLKVGPATARKLWGSPTSPEDVTSMFSRLITGDLASIPWSDEVDPTAGLHGPGSLRA
ETSVIREQILDLIQRKHYWTLASQPAVDGARSNDEVFGWGPRDEGFVFQKAFVEFFCSRS
EWENVLRKKLVETPQDHLSWMKTDAEGVYESSDNITNGASKPGRSSSKRVPGQSGVNAVT
WGVFRGKEIVTPTIIESESFRAWGEEAFAIWAEWRRCYARGSSEEQTLEALRKDLVLVNV
VGQDYVGGHEGNGRELWDVLRA
>A0A1Q7SYJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_20CM_58_21|TrEMBL
MKIYDFNERLKDAILVADGAMGSMLHEAVGFERCFDELNSTEPEAVFRIHQAYIEAGAQI
IETNTFGANRFKLAPLGLAEEVQRFNSRGVKIAREARESAAREVLIAGSIGPLGLGVQSR
HPSPEEIQEIFHEQALALEERGVDFYILETFSYIEEVLLAIDAIRSFSGLPIVAQLTYAE
EGTTYGDVRPSDAAAQLKNKNVQVIGANCTLGPQALLPILEELAAVDGLRVSGMPNAGFP
KREGDRIVYPRSSPEYFALFAREAAALGVRILGGCCGTTPAHIRAMAEAVKLLRPSETHP
VVRSVETVLRPVPVARREPDSRFWKQLQKKEFSVCLEIDPPKGLSLDRIFEQVDKVMASK
KVDAIDINSGAMARVGMDALIVAGALEARGIETVPHLTTRDQNIIGLQAALLGAWTVGGV
RNVLAITGDPPSVGDYPETSGVYEVDSVGLVKVLNRLNQGTDWAGKTLGGATNFTIGVAV
NPVADDLDNEIERFHAKVEAGAHFAMTQPLFDPQHWHAFLNKLGGKPVIPVLIGIWPLNS
YKQALRLSNEVPGIVIPEPLLKSMEAAGSAARDRGFEVARDMLAWARTELAGAYLIPPFK
RYEEILEIL
>A0A2I8D5D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. ASNIH5|TrEMBL
MGFHSARQVEALNQSLADLGGDISVSFEFFPPNSEGMENTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLENDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQA
>A0A2N7W771|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trinickia soli|TrEMBL
MNPIEISFEFFPPKTPDGVEKLRATRAQLAMLKPKFVSVTFGAGGSTQQGTLDTVLDMAK
DGLEAAPHLSCIGSSKESLRAILEQYRSNGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAAYPEYHPQARSPRHDLENFARKVKAGANAAITQYFFNGDAYFRFVD
EARKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDKEAIRAFGLDV
VTQLCERLVKEGAPGLHFYTLNAATATKAICERLA
>Q2K697|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium etli (strain CFN 42 / ATCC 51251)|TrEMBL
MALKNEGRGRNFGISFEFFPPKSEEMEGQLWDTVAKLQDWDPDFVSVTYGAGGTTKAPTL
SAVTRFLSQTPLATASHLTCVGATKEETHQMIDTFRKVGVKHFVALRGDAPGGVGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGISIPIVPGIMPIQNLTQLKRFAGACGAVIPAFLDERFAGFDD
KPEDRAKVAAEVAAEQIEDLVRRGIGDFHLYTMNRAPLVSAVLDNLGYSRRASKSAGAAA
>A0A127NVJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium simulans|TrEMBL
MRQRTALSFEVIPPRNDADASKTSELLAVLQSYHPDYIAVTSSQRSGWLRGTAAFIEQIS
RTTSMRPLAHLACTAGSPEELSEWVDVLVDSGVRGFLALRGDLPEDGMPVGYLQHADELI
RLIRRREAAQAARFAAGNLAVGVACYPNGHAESANADEDIDVLLAKQRLGANFAITQLFF
DPEDYARFYQRARLAGVRIPLIPGIMPMTSVARLERMAGLSGLDVPPKVRAALAAAKTPE
EEQEIGMELTAELARGVLRAGAEGLHIYTHNNSAITHDLLSRIGVNR
>A0A2T0N042|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea fuscirosea|TrEMBL
MIVTFELICEIEPPTKPDLKHVRHQIGTMSTIAHSFLIPDNHIGRATVSSVAVAHEVESM
GGRGIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVYGDKPTSGNRTSDLTVRSMIAEAR
EFSPGFRVGAAAALRPLPAWKRSADFLFSQVSYSVEAQVRWREEHPADLPVYAGVMVLAS
ERHARTLAAAIPDIALPEDLVRRVAADRMAGVEAACEQVLALRDSGAFAGVHLIPVSRYR
DVESRLAPALK
>A0A250FKM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga gingivalis|TrEMBL
MKVTEHIAKAQGKTLFSFEIVPPKKGNSIEELYKNIEPLLEFKPPFIDVTTSREEFYYKE
HPNGLLEKKIVRMRPGTVGICSAIQHKYNVDTVPHVLCGGFTREETEDLLVDCFYLGIDN
IMALRGDAMKEEKYFRPTKNGNVYALDLVKQINDLRKGIYLHDTLENNTGMDFCIGVAGY
PEKHIEAPSKTFDLEKLKEKVDNGADYVVTQMFFDNKQYFDFVEKARQMGINVPIIPGIK
PISVRRHLNIIPQAFFLDFPEELVKEIEKCKNNNEVKQVGIEWAIAQSKELKQAGVPSLH
YYSMGKSENIIQIISKVF
>A0A2T6GL60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas protegens|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLAGYNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLKQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLRNFARKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A5N8VI06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces adustus|TrEMBL
MSSVPEAPAGGAPSFSFEFFPPKTGQGERTLWNAVRRVESLSPTFVSVTYGAGGSSRERT
VEVTRCIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGIRDVLVLRGDPPGDPNGPWT
PHPAGFTHARELVELVRSLGDFTIGVAAFPEMHPRSPDWDSDIRHFVAKCRAGADYAITQ
MFFRVEDYLRLRDRVAASGCDVPIIPEIMPATDVRQIRRFAELSHAAFPEDLAHRLDSAR
DDPAAGHRIGVEHATAMAGRLLSEGAPGLHYITLNRSTAALDIHRNVLAAQAASSARVS
>A0A1Q6N833|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:62_40_43|TrEMBL
MIKDLFHTNRPTYSLEVFPPKKDADVSVIYDALDEFKTLHPSFISVTYGAGGNTAENTFA
IASYIQNQCGIEALTHLTCAAIPDRLFLKNFLTNLYRNGIHNLLALRGDKPQWMSDEQFD
ARFYDHASDLVTDVKEMFDFSVAGACYPEVHQEAASLSEDIANLKIKVDKGVDFLITQLF
YDNETFFRFLDEARNAGITVPILPGLMPITSAGQVKNIIGMSGTKIPKELVDAIEKYKDN
PADLKKAGLDYSKRQMENLLAHGVDGIHLYSMNKVEIARAIYE
>A0A3A6QU15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sinensis|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEKTLWNSVHRLKTLNPKFVSVTY
GANSGERDRTHSIIKEIKTGTGLVAAPHLTCIDASREELIQIADDYWSNGIESIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVRVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGIRPNV
>A0A1V3I9Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter heidelbergensis|TrEMBL
MSYAKEINNLNQTIADFNKKINISFEFFPPKNEKMENMLWESIHRLKVLEPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDASPEELKQIAKDYWDSGIRHIVALRGDEP
KGYEKKPFYAADLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIESYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPTWLAKAYEGL
DNDPTTRNLVAASVAMDMVKILSSEGVNDFHFYTLNRSELTYAICHMLGIRPKV
>A0A257F8H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia sp. PBBBR1|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRGILNTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGEAFHIEVAAYPEYHPQSRSARHDLENFARKVKSGADSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A8B2U4Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aggregatibacter segnis|TrEMBL
MSYAKEIDNLNQHLADLNGKINVSFEFFPPKNEKMENILWESIHRLKVLKPKFVSVTYGA
NSGERERTHGVVKHIKQETGLEAAPHLTGIDATPDELRRIAKDYWDSGIRRIVALRGDEP
KGYEKKPFYAADLVTLLREVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPAWMAKMYDGL
DDDQTTRNLVAASIAMDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGIRPTL
>A0A829GIR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei subsp. paracasei Lpp123|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A5KL25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ruminococcus] torques ATCC 27756|TrEMBL
MKIIDRLKEDKIHISFEVFPPKTDAGFEKVIAATDAMAKLNPAFISVTYGAGGGTSKNTA
KIASHIKDDLGVVSLAHLTCASSTIEEVRDVIENLKENGIENILALRGDIPEGMPFPNGN
RFRYAYELIEEIRKHGDFCIGAACYPEGHVENEHKAEDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGINVPVLPGIMPMTSEKQMKRSQELSGTVFPRRFLALLDRFGSSAA
AMEQAGIAYATDQIIDLLSNGVNNIHIYTMNKPHVAAAIMNNLSEIIKA
>A0A2M9MC60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02959|TrEMBL
MALGTASTRTDRARTVRDLLASGKRSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTAELRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVRHPDGIGHAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADFAITQMFFYPEDYFRLRDRVDAAGCPTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQRP
>A0A413AJ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVHRMAERNASRIPDKLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A413F3V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF04-24|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKLASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A264DZL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. VTT E-133280|TrEMBL
MTPPKASHSPEKISEIAQKQVERLQNVDLDALILYDVQEEAERVDHERPYPYLPTIDPAI
YGDKYLRQVEVPKIIYRCVGNDTRASFADWIKTDESEDRFSVYVGASSSKQEVKLNLPDA
YKLSKQLNSNLNFGGVVIPERHIKKNDEHIRVVEKINNGCNFFITQATYNVEASKNLLSD
LYYYYTNKGFEMVPILFNLAPCGTAKTLQFMKWLGISIPGWLENELKYSNDILDKSIQLS
QKIFEELFEFGLEKGIPIGCSIESVSTTKLEIEASIQLAKDVKAFLDKKLLSPESR
>A0A420D1C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. AG855|TrEMBL
MAQNERATSQPSKLKVSFEFFPPKSPDMADQLWQTVEALQPFQPDFVSVTYGAGGTTREP
TLSTVGRLIAQTPLATAAHLTCVAATREEVRLVVDEFKALGVRHFVALRGDPQGGVGTRY
EPHPGGFENAADLVRGLREMGDFEVSVSAYPEKHPESQDEAADIEMLKRKVDAGATRALT
QFFFDNDTFERYLNRVRAAGITIPIVPGIMPIQNLSQLKRFASMCGASVPERLDRRFEGT
EGDAQARAEVAADIAAEQIADLAKRGIAEFHLYTMNRAPLTVATLTRLGLGAQSSSLSGA
AA
>A0A857FJD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataeibacter xylinus|TrEMBL
MTDRLNGLVSEERIGNLLSCSCDMPPPALSFEFVPPRTEPMEQRLWQCIRRLAPLSPCFA
SVTYGAGGSTQASTYATVLRLRRETDLVPAAHLTCVGATREEVDAIARSYWEAGIRHIVA
LRGDPPAGTADYTPHPGGYAYARDLVAGLRRIADFDISVAAYPETHPAALSPEADLDNLK
SKLDAGATRAITQYFFDASTCLRFLDRCQSAGINAPIIPGIMPVSNYEQVARFSALCGVA
VPAWLRRLFEDTDENPELRRIVASIVAVEQIRTLQANGINEFHISTLNRADPTYAIAHIL
GLQEIGRSILDHVADYPEQEETSDEREAETNSDTAGRTEEGASPFMLRTMFG
>A0A8J3BCL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yeosuana aromativorans|TrEMBL
MKVTEHIKKANGNTLFSFEVIPPQKGKSIQDLYNNIDPLMEFNPPFIDVTTSREEYVYID
KGNGLLEKRMTRMRPGTVGICASIMHKYGVDAIPHLLCGGFTREETEYVLVDCHYLGIDN
VMALRGDSMKDEPYFKPAEGGNAFASELVAQITDLNKGKYLHDNVLVEQNADFCIGVAGY
PEKHMEAPSLASDLKRLKDKVDAGADYVVTQMFFDNKKYFEFVDKAREMGITVPIIPGIK
PIAVKRHLQILPQVFKIDLPQELVDAVEACKDNNAVRQVGIEFAVQQSKELKAAGVPVLH
YYSMGKSDNIKAIASQLF
>A0A6J1W305|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Notechis scutatus|TrEMBL
MELAEKTPIARAFTMVNEILPMSNGLGTRSDGGNSSSSGESSQNSSRCSTPILDTERHER
LREKMRRRQESGDKWFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSD
KETSSMMMATTALNYCGLETILHMTCCNQSRETITAHLQKAKRLGLKNIMALRGDPVGEE
WEEELDGFNHAVDLVKHIRQEFDDYFDLCVAGYPGGHPEANSYIDDLKHLKEKVSAGADF
VITQLFFRTETFLKFLMDCQAIGISCPVVPGIFPIQVKASCIQVAFKLQQFV
>A0A0E3L272|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. WWM596|TrEMBL
MLFNFREKLNSRKFLVTVEVSPPKGTRFSASLEDTCQLKGAVDALNVTDNQCSIMHMSSL
AFSKLLLDQGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDHPICGDHPGSKP
VYDLDSVQLIELVRKLDSGIDFAGKKLDGSTSFCAGAVSGIDPENILQLIKLEKKVRCGA
DFIQTQAVYDVGRFEEFTEAVNHLEVPVIAGLIPLKSLGMAEYMNKNISGIHVPEETMLR
MKDAASPIEEGLLIASETIKELTKLSRGVHIMPIGSHKNTPRLLSMAGISDKQRDPENSL
>A0A7Y1C913|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. WS 5018|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKAELRELLNLYKSAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVQTPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A843RMU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteitalea sp|TrEMBL
MQSFREALEERVLICDGAMGTELYARGVFLNRCFDELNLTRPDLVADVHKEYVRAGVDLI
ETNTFGANRVKLASFGLVERLREINVAASQLARHAAHGTTFVAGSVGPLGIRVEPWGKTG
LDEAEEYFREQAEALAEGGVDLFILETFRDVNELGAAVRAVGRVSQAPVVALLTTGEDGS
THDGVPPEEFTPQLEAFGADVIGVNCGVGPAAMLDTIERMAALTGRRLAAQPNAGRPRDI
EGRNIYLCSPEYMASYASRFVQGGVRLVGGCCGTTPEHVRQIRAAVHHASVARAVRPADL
SAEARSAKAEARHAKAGGAPSGRAARPSVTPVPRAEKSRVASAFARGDFVVGVQLVPPRG
HACTALLDAARTAKARGADFVYVPEHGNGVARMSAIAAALLVEQQAGIETLLQYACRDHS
LPAIQADLLGAHAMGLRNVLLVTGEPIRHHDYPDATLVFDVDSIGLTNAVARLNQGEDVG
GQPIGPPTGFHIGVTANPTAVVLEQEVRRYRYKVEAGAEFLVLQPIFDVENLTAFMERLG
RPRLPAVATVQLLGSVRDAEELAHEVPGVHVPARVLERMTAAEAAGSEVETGLEIARELV
DALRPLTQGVLIAPARDQVEHALGLLVEGRSHRGAAGCSQVRSTV
>A0A257RJL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 21-73-9|TrEMBL
MRVDELVAAGLTRSFEFFPPKSDEERLVLETTLVELEELAPSFVSVTYRGGAASRQRTFD
LVTSIEAKGLTAMAHLICVGHGRAEMRGLLARYAEAGVENVMALGGDTPGGAAPTGELRH
ASDLVELVREAGPFCVGVGAHPQGHPRSPDRASDRRRLAEKLRLADFAVTQFFFEPEEWT
RLVLELAELGVDKPVLAGIMPVTTLSGVARMAEMGAGVPDWLVERLEAGHHRGGPGAVRA
EGVAAATELCEALLEAGVPGLHFYTLNRSSATREIHRALFS
>I9SZ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides ovatus CL02T12C04|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEIAKIIY
>A0A0B2BYR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceibacterium mercuriale|TrEMBL
MNDSRTAPLLAGAAGDVEVSFEFFPPRSDAALETLLATASGLASLGPRFVSVTYGAGGST
RGRTQEAVLGIARETGLNAAAHLTCVGASRAEVDAIADQYWHDGVRHIVALRGDMPEQDQ
PYAPHAEGYANAAALVAGLKRLHPFEVSVAAYPEAHPDSTDMAADLDNLWRKVDAGADRA
LTQFFFSADTFFRFRDLAAARGIDVEIVPGILPVANVAQLRRFAGTCGAAIPPAIDRVLE
GLDERPAARQLVAATIAAELCGALYAGGVRQFHFYTLNRAELTYAICHLLGLRPAPATAE
QKAVLTAA
>A0A2E4R4G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp.|TrEMBL
MSSSRALSLEFFPPRDENARGKLTAAAKELEVLNPAYVSVTFGAGGSTREGTADAVGLLQ
KLGYEAAPHLSCIGASRVVLGDILQYYKEQGVRRLVALRGDLPSGMGMNKGELHYAVDLV
RFIREQTGDWFHIEVAAYPEVHPQAKGAQADLNHFVEKVRAGASSAITQYFFNADAYYDF
VDRAREKGVSVPIVPGIMPITNHNQLVRFSDMCGAEVPRWIRQRLSDYGDDLASIRAFGA
EVVTRLCQDLLDQGAPGLHFYTLNNAGATLAIARRLT
>A0A0R1XB12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schleiferilactobacillus harbinensis DSM 16991|TrEMBL
MQINQLFKDRPVISFEVFPPRKNATAASLRKMDETLAVLSDLHPDYVSVTFGANGALQAT
GTLATASYIKDTYGIETVAHLPASQLSADQIHGLLNELQAHGIENILALRGDIPAGGRLS
NDFPHACDLIRYIHQCGDFNVIGACYPEGHPESPDLATDIHYLKDKVDAGASHLISQLFF
DNQVFYDFIAQARAAGITVPIQAGIMPVINAHQIERMATMSGVALPEKFTRMMARFQDNP
VAMREAGIAYAVDQIIDLLVHGVDGVHLYTMDNADVAQRIFAAAEQVIHA
>A0A178XC91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. M39|TrEMBL
MTSVIERLRGDGPAFSVEFFPPRDEADEAVLWKAIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLCPMAHLTAVDHSVSELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPEGLTYAEELVELVRSLGDFCVGVSAFPYGHPRSADLESDTKHLVRKFRAGADFAIAQ
LFFEAEDFLRLRDRVAAAGCDALVLPGIMPLTTLRTLHTTIKLSGAPASQRLLDRLEPFS
GDPRAFRAAGIDWVTELCEKLIAEGVPDLHFYTFNRSKATREVVTRLGLVPARA
>A0A3Q8XKB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter haemolyticus|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDADIKRFIEKVQAGANAGITQFFFNPDAYFYFI
DRLEKAGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLSAYGDDSASIKAFGHE
VILKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A564W6T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia luti|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPGTIEHLMKYRPEYISCTYGAGGGNVGANRE
VCQMIRNAGTVPVTHFTVIKNTKEGIRQQLEQYLADGVNHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A7C4A6E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MNDSTLKRAIESGEFIIIGECVPPRNSDPSPIRSCASQLSDKVHAVGAVESNDGPRLSAL
ATCVHLASAGVDPILHLLTRDMNRIAIQATILGALSLGVHNIFCTAGRHQILTNEPHARG
VFDVDSLQLVGIANGMRNGVLAGGREIQPQPQLILGTDTNPYAQPMELQILSLEKAVAQG
VDFVVTQPVFKLEEFATWLSLARERGICSRTCILPSVKPLTSAGEAADLRETHKAFDIPE
QLISGLKDSKDPRATGIEHVVHTISEIRKMEGIRGLYLMTGEDPSLAVEIMAASGLSRGS
>A0A7K2DKA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
LKSLDAAIEALPAGSRVSVTASPVKGQDATCEITERLMELGHEAIPHVSARMVTDRARVS
ELASWFRSAGVSTMFLVGGDVESPGAYSDAASFLRDLLECDHGLSTIGVTAYPHGHPLIA
EEVLHEALHTKQALLAEAGVEGYCSTQMCFDPARIEGWLRGERAAGLTLPVHLGISGVVD
RAKLLTMGARLGVGPSLRYLRKNRAAIMKLMTSPNYDPDHILMALSPSLDDLGVTGLHVF
TFNQVATTVTWQSSHHG
>A0A7V3I4H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MPQPRKLPSVFRERVVVFDGAMGSLLHERGVHPSRPFEELNLKAPHLICQIHAEYIQAGA
DAIETNTFAANRFRLAGYGLEDQVYELNSAGARLARNVAGPNIVVAGSIGPLGVRLAPIG
PLTVDQIKAAVVDQVRGLVEGGVDLILLETQDDLNVACAILEAVFGDCDLPVMCQFTIGN
DLTTSTGDTLDDIVVRLSDYPISSIGVNCGVGPEGALRAVQALSEISELPISAQPNSGFP
ANVDGRRLFISGAGYFSDRGAEIVQAGASIIGGCCGTTPAHIEALAAKAKTLPLPVGRAV
RTPRSRQASPAAVCKRSPLLSKMNGGFVTVEVTPPKDTNYRELVEKLRPLVEAGVSAIDV
TDNPMASMHMSAIAFAHLVKEELGVATILHLTCRDLNLLGMHSALLGAAALGIDAILALT
GDPASVGDFPGATSVFDVTSDGLARIINSLNCGVDYIGKEIGRPTNFAIGAAFNPFADDM
EKELARLAK
>A0A3S5BCT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mannheimia haemolytica|TrEMBL
MNYATQIDALNQHIADIDRKINVSFEFFPPKNEKMETILWDSIDRLSPLKPKFVSVTYGA
NSGERDRTHSIVKSIQEKTGIISAPHLTGIDATPEELKVIAKDYWDSGIRRIVALRGDIP
KGYDKALFYASDLVALLKSVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVSIGIDCEIVPGILPVTNFKQLQKMAAVTNVKIPTWMGKMYEGL
DDDQTTRNLVAASIAMDMVKVLSREGVNDFHFYTLNRSELTYAMCHTLGVRPDLTTA
>A0A6J3JP99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sapajus apella|TrEMBL
MDLRKARVLPAGHYCPSLGIRASQAGSVRFSVPPSIRNPAMVNEARGNGSLNPCLEGSAS
SGSESSKDSSRCSTPGLDPDRHERLLEKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCHQRLEEITG
HLHKAKQLGLKNILALRGDPTGDQWEEEEGGFNHAVDLVKHIRSEFGDYFDICVAGYPKG
HPDAESFEADVKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVRLCRELLASGLVPGLHF
YTLNREVATTEVLKHLGLWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKNYYLFYLKSKSPRDELLKMWGEELASEESVFEVFVHYLS
GEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGVLTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPGLQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRAIIQYIHDNYFLVN
LVDNDFPLDNCLWQVVEDTLELLNRPTQHEREAEAP
>A0A7W4HW74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
ADVKQVGIEWCTAQSKELKERGVPALHYYSMGRSEGVKQIVNEVF
>A0A849J0T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MVAGEAPMGALFSKARIEVIPTKTVGDQVEQWISKDVTMAVTASPVKGLDSTFELAERLC
DAGYNVVPHVSARLVVDEKHLAEIVARLTERKISDVFVPAGDADPPAGKFDSSLSLLEAL
DHMGRPFERVGITGYPESHPKISDDVTVQAMWDKRHFASYVISNLCFDPTIIKHWVERVR
KRGVKLPIYLGVAAPIDRTKLLDVASKIGVGESTRFLTKHAAWFLRMGTPGGYSPNRLLQ
RMGPTLTAESSLIEGLHIYSFNQIRQSEDWRVAQLERFGVALQGKALESHPAN
>A0A3Q9IBQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus lutimineralis|TrEMBL
MRPDLRQTWKNEVLIGDGAMGTYLHQLGFSVGISYEEMNLTRPDVIQDVHRRYIDAGARL
IETNTFSANFYKLSKFGLEDQVADINRAAARIARQAAGPDIFVAGAVGTIRGGKRVNVTD
QELVKYFDEQMTALLTEDVDALILETFYDLREMRLALGRARHLTPLPIICQFAVDQLGRT
LDGYSIEEAFGILQAEGADVLGFNCHSGPKGIMSVMERLNGPLNMPLSVFPNAGLADYVD
GEYVYGATPAYFGECAVSFSDLGSRLIGGCCGTTPEHIAATARALADYNPASLTEGRSLP
TVLESIQVLERELDNGDNNRADNTPNIVDLVEERHTVIVELDPPRDLDTSKFMAGAKALK
EAGVDALTLADNSLAVTRMSNMALGSRVQSEIGLRPLIHIACRDRNLIGTQSHLMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDLTSFEIIRMIKQLNEGTAFSGKPLKHRANFVIGA
AFNPNVKYLNKAVERLEKKIASGADYIMTQPVYDPELIVAIREATAHLDIPIFLGIMPLA
SGKNAEYLHNEVPGITLPESVRKRMEGLQGAEGRAIGVEIAKELLDTAMQHFNGIYLMTP
FMFYEMTVALTNYVHEKSMHRASHLSRS
>A0A2E1WJU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MAKFWRVGRIDRVTAAPLRRRLLHNGRFEVIPLKSLVPQLQHLPSGASVSVTASPNKSLE
DTWELTRDLRDRGFRPVPHLAARMVKDHRHLERLIKELRELELNELFIVGGDAPEPFGPY
EDSIQVLQAILDLDHRLNHIGVTAYPDGHSFIEXXVLGQSLRRKQDLLQQAGIDGHAATQ
MCFDPDTIRDWLRDERTXGLKLPIHLGXPGAVERSKLLSMGAKLGVGASLRYLQKNAGTL
TRMVLPGGYNPNKLLSPXAPDLAELDIQALHIFTFNQIASTVSWRDEXVSALKI
>A0A7K2A7M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MLSKLRRGALSAETLGARHHRLHLVRDLTFEVIPLKSLDAAIEALPAGSRVSVTASPVKG
QDATCEITERLMELGHEAIPHVSARLVTDRARVSALAGWFRSAGVSTMFLVGGDVESPGA
YSDAASFLRDLLECDHGLSTIGVTAYPHGHPLIAEEVLHEALHAKQALLVEAGVEGYCST
QMCFDPERIEGWLRGERAAGMTLPVHLGISGVVDRAKLLTMGARLGVGPSLRYLRKNRAA
IMKLMTSPNYDPDHILMALSPSLDDLGVTGLHVFTFNQVATTVTWQSSHRG
>A0A7W4HNK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIEKANGKTLFSFEILPPLKGQNINLFFDAIDPLLEYSPSFINVTYHREEYEYVE
HENGLLERKVVRKRPGTVGICAAIQNRYHIDAIPHILCGGFNREETENFLIDLDFLEIDN
VMALRGDVMKSETYFKPEKNGNAHASDLVHQIKQMNDGVYLDHNIELPSPTNFCIGVAGY
PEKHMEAASLHQDIMSLKKKQEAGAEYVVTQMFFDNQKFFEFVDKCREEGITIPIIPGLK
PITAKSQLSMLPYRFKVDLPDDLVIEITKCKTAADIKQVGIEWCTAQSKELKERGVPALH
YYSMGRSEGVKQIVNEVF
>A0A0D0EMG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium hibernum|TrEMBL
MKVTEHIENAKGKTLFSFELIPPQKGKSIQELYDNIDPLMEFQPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGITN
VMALRGDAMKDEQSFVPKVGGNKFAIDLVRQINDLNCGKYLHEVMDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFNFVEKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNADIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A3A9UFN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVIDHIKNTKKETQFSFEILPPLKGQNVQSIFDNIDPLMEFKPPFIDVTYHREEYVFKE
MEDGLLKKQVVRKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLNFLGIDN
VMALRGDAVKSETYFRPEKEGHNYASQLVEQIQDLNNGIYLDDDLQNTFKTDFCIGVAAY
PEKHMEAPSLDSDIHFLKKKIKNGATYIVTQMFFDNQKYFDFVKKCRAGGITVPIIPGLK
PIATKKQLNLIPHRFHVDLPETLISEIIKCKNNEQVREVGIEWTISQSKELLKADVPVLH
YYSMGKSSNIKAIASEIF
>U2K5L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus callidus ATCC 27760|TrEMBL
MKIASLFSEKTVFSFEIFPPKKTSPIETVYDTLEALQDLKPDFISVTFGAGGSGNGENTL
AIARRLKEHYGVLPMAHLPCIHYTKEQIDNILKQFQENGIENVLALRGDRVEGMEPAMDF
VHAADLISYIRSFGGFDIAGACYPECHPEAPNMDTDIRHLKEKVDAGASHLITQLFFDND
SFYDFRYRAARAGVNVPIEAGIMPVTNRKQIERMVTMCGASLPRKFTKMVQRFEDNPEAL
RDAGIAYAIDQIVDLVTDGVDGIHLYTMNNPYVARKISEAVNGIIKAAPKC
>R6FP44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:633|TrEMBL
MKVIDLINSTQKTAFSFEILPPLKGTGIEKLYETIDLLREFDPKYINITTHRSEYVYKEL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEDTEYQLLDLQFLGITDL
LVLRGDKAKHESVFVPEPGGHAHAVELQQQINNFNKGIFVDGSEMKITRTPFSYGVACYP
EKHEEAPNQETDLYWLKKKMETGAEYAVTQLFYDNRKYFSFVERARQEGITIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTHELLKCTNDDEARHVGIEWCVKQCRELIDHGVPSLHF
YSIGAADSIREVARQIY
>A0A0D8BM92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia torreyi|TrEMBL
MASYPVRMQESMAGHERPARGFELICEIEPPTRPDLTHARHQIGVLSPVTDAFLIPDNHI
GRATVSSIAVAHEVQTMGGRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVHGDKPTA
GNRTSDLTVRAMMDEARAASEDPAFADSPAFRVGAAAGLRPLPAWKRAADFLFVQVSYSV
DALLRWRDAHPVALPVYAGVMVLASAGMARRLAATIPDIDIPDDLVHAVERDQVAGVEAA
CDQVLRLRDSGAFAGVHLVPVSRYRQVATRLEDLL
>A0A2D8LQK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MALFKKNEVPEIVESDEARAHREHLTRTFTIEVIPMKSLDNAREHLPAGAPLSVTASPVK
GLEETQRLTEEFQAAGFEPVPHISARMVRDRAHCAELAHWLRDNGLKKMFLVGGDQDPPG
EYFDAVLFLQDFLEQDHGLEGLGVTSYPDHHAFISDEKLHEALHAKQTLLAEAGLPGWCS
TQMCFDAEVIEAWLRKERAEGLTLPVHLGVSGVVDKAKLMTMGVRIGLGASLGYLKKNRA
AITKMLTSTSYDPNDLMMPLSNAALELGIEGVHMYTFNQIEATEQWRAEALAELAG
>A0A1X1FVF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. tigurinus|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKGKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A0M8PHJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium nordicum|TrEMBL
MHIRDKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEATENGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNTDVDQLIDHLKEKVDAGSSF
VVTQMFYDAENFIEWLKKCRAKGITIPIIPGIMPIQTYASFIRRSNWTKVQVPPQWMEAL
EPVKNDDSAVRDIGKSLIADMCRKLFAAGIKHLHFYTMNLAQATQLVLKELDLSPSDESP
IQRALPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISDIFVNFLTGKLDRLPWSDSPITTEAQDIQEDLLK
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLLDELITRIEKNG
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCHDAASPSRQLIQHVMDDWYLVNIVDNDFHRSNAVFELFNGLEIKDLNIEMAGKPLTNG
HAEPNGVAAN
>A0A431J1T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIQNANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LENGLLQKKVVKKRPGTVGICAGIQNKYEVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGHAYASELVTQISNLNKGIYLDEDLQNSTKTDFCIGVAGY
PEKHMEAPSMDSDIHFLKQKIKNGADYIITQMFFDNKKFFDFVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNYHVKQIGIEWCTQQSKELIAAGIPILH
YYSMGKAENVKAIAKEIF
>A0A2E5P2C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MRKGGCVATRNQANRAVQKRLLEGMTYELIPLKNLADQSQHLPAGATVSVTCSPAKTVDD
TLDLCAGYAEKGFTVIPHIAARMVEDEGHLDRIVQRMNALDIRTVFCIGGDADPRGPFTD
AAGFLHSFLDRRPNVDVVGIGSYPDGHATIPDQALVDALVEKQELIREAGLKGYMATQMC
FDADTIGDWLEGRRAAGVDLPCHLGVPGAVDRARLLAISIRLGIGHSTRYLRKNRTSVIR
LLSPGGYDPNKLIAPLSYRADELNIAGIHCFTFNAVDTTESWRRKSLRKLGS
>A0A2E8R4F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKIIDHLKNXNDSSQFTXEILPPLKGXXLESIFDAIDPLMEFKPPFIDVTYHREEYVYKE
LDNGLLQKHVIRKRPGTVGICAALQNKYNIDAVPHVLCGGFSKEETENLLIDLDXLGIEN
VVALRGDSLKSEVYFKPSVDGNSFASDLVKQIVDLNKGKYLDEEIQNNAKTNFCIGVSGY
PEKHIEAPSFDSDIHFLKKKIDAGAHYIVTQMFFDNQKFFDFQKKCMENKINVPIIPGLK
PISTKKQLNVLPQRFYVDLPDDLIKSVIKCKNNDQIRQVGIEWCIEQSKELKKAGVPFLH
YYTMGRSDNIKSIAESVF
>A0A3C2B8M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSTNTRQLIADARYEVIPMKNLEAQIPHLPAGCSVSVTCSPAKGQQATLDLTARLLDLGY
IAVPHLSARLTEDDVAVKKMAEFCRSHGVQEVFLVAGDPPEPAGPYDGVVAFLRDFLGHD
HGLRRIGVTAYPDGHALIPHQVVHEALHGKQALLAEAGVDGFASTQMCFDVSQWKQWAAA
ERAAGFTLPLHIGVPGVIDRTKLLTMGMRLGIGASMRFVKKQGGVLGRLFSPGGYDPMKL
LQPLGKAADTLGVEGTHLFTFNNVEATAEWQQRMLAKLQ
>A0A242CWT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus sp. 3H8_DIV0648|TrEMBL
MSSTLSFEVFPPNTQIGSEKLFKTLKELQLLQPDFISVTCSNNRQTIEETTLKVANYIHK
ELNVPTIAHLPAAYLSQAQLAELVTQLDQIGIDQILALRGDILPDLPPKQDFTYASDLID
YVKKEAPHFHISGACYPETHPESQNRLEDIKNLKHKVSVGCEQLITQLFFDNELFYHFQE
SCYLADIKVPILAGIMPIVNRNQALRLIKTTNTKLPRKFLAILEKYEHDPIALREAGLAY
AIDQIVDLTTQDVSGIHLYTMNNAEVAKHIYHNTKNVLHGDIKAG
>A0A175RC16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas ureilytica|TrEMBL
MIQRRSQRSPFRVSFEFFPPKTPKMEEGLWDSIQRLAPLSPDFVSVTYGAGGSTRERTHH
TVKRILSETPLKPAAHLTCVDASRDEVDAVVRQYRETGVRHFVALRGDGQAGAGGAYEAH
PNGYRNAVDLAAGIKAIDPEIEISVSAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNDVFERYVERVRRAGIYVPIVPGIVPIHDFTKISRFSAATGASIPLWLAERFEGLEN
DPQTHSHVAAAVCAEQVLDLAERGIGDFHFYTMNRADLVYSICHILGLRPSAGGDDRTDR
IEEAA
>A0A7Y0AN88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium antibioticum|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTPGGHTSAMDLVHQINDLGRGKYLHNDELACDELNKFCVGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVTKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEELINEVEKAKNNEAVKQIGIEWAITQCRELLDFGVPVM
HFYSMGKSDNIKKVAGELF
>A0A6A3YSY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora fragariae|TrEMBL
MDPPQTLDTCDSRLLPNDSLATSVSAFIKWEEAAALEAFPLAVVPSNHPHTREKGSKMPR
VSSIHVTKQKERHEEADELAATKFVLDDSTVWTGLSTEDTRAAGESEGDQERLLQRLHLV
QGLLTFVRMLRRSRGLQAEEEDDEAKTSAQWTPEWASLKRALGLQRLKAKQDAGADFIIT
QFFFDVDNMIHWIADCKDAGITILPGYLSIQNYSSLCKFTSWCKTRVPESVLAALDTIKN
DDAAVRRYGTQLAAETCQRLLAAGVNSLHFYTMNLPRP
>A0A7U4IRP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium etli bv. phaseoli str. IE4803|TrEMBL
MALKNEAQARNIGISFEFFPPKSEEMEGQLWETVSKLQDWDPDFVSVTYGAGGTTKAPTL
STVTRFLAQTPLATASHLTCVGATKDETHQVIDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGSFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGYED
RPEERAKVAAEVAAEQIEDLVRRGIDEFHLYTMNRAPLVSAVLDNLGFSRRPAKSAGAAA
>A0A7Y9ZNF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides aromaticivorans|TrEMBL
MDLATRIAAGQGGFVLFALTPPRQSTPAERLPEIARATVERLDHLDLDGLILYDIDDESS
RNPAERPFPFSPTVDPSTYRAEHFGSWRTPVIVYRAVGKYQPEGLRTWIAEQDPRSTLTV
MVGAASSGATPPLSLADAQALRAEANPDLLLGGVAIPERHRRRENEHLRLIAKQEAGCRF
FVTQVVYDVNAAKNLVSDYRYACAERGTAPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLRHATNPLRASLEQSAATAAELVEFCRRLDVPFGLNVESVSIRREEIEASVELAARL
GAQLRVSPDAR
>A0A3B0T6I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
EPYIPHPDGYANAAELAAGAMKIAPFEITVGCYPEKHPDSPSMNADIEMLKRKIDAGATR
AITQFFYDNTAYLRYRDTIRAAGIDIPIVPGIMPVTNFNGMRRMADICGTTVPGRLVKLF
QNLEDDPSTRRLIAATVAAEQCQELAEHGVNHFHFYTLNRDDLAYALCHMLGVRPTVKAV
DHAA
>A0A3B0S6S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MTHSPPPSTSAQPIEVSFEFFPPKTPKMEAKLWQSVEKLAPLQPTFMSVTYGAGGTTRER
TRETVLQMAKKTGISVAAHLTCVETSKAQVDATIQSYRDAGIRHIVALRGDPASGISGIY
QPDENGYAYASDLVRAIKCSGEMAVSVAAYPERHPASANWQSELDNLQRKIDAGADQAIT
QFGFEANTLIEFRERLHKAGISIPIVPGIMLQPNFTGLVRMAKMCGTCIPKRMFELFEGT
EDDLVSRQLLTANLVAEYCIKLQEAGFHRFHFYTLNSADFAYTTCRVLGLKPQSEPNK
>A0A8J5BHN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yarrowia sp. E02|TrEMBL
MKISHKLEKAHEADSTPTFSFEFFVPKTSQGVNNLYDRMDRMYQLGPQFIDITWNAGGRL
SNLTNEMVATAQSALGLETCMHLTCTGMPKQLVENALQSAFDGGCQNILALRGDPPVESE
KWEAVDGGFRYAKDLVKYIKSKYGDYFDIGVAAYPEGTPEEPDVDILIDHLKEKVDAGGT
FIVTQMFYDTDNFLKWVDKCRAKGINVPIIPGIMPISTYASFMRRANWCQIQIPQDFLDK
LEPVKDDDMRVRELGTQLVADMCQKMLDSGKIKHLHFYTMNLEKATVMVLERLNLPAQDS
AVAPLPWRPSLALGRQDESVRPIFWKNRKQSYVARTQDWDEFPNGRWGDSRSPAFGELET
YGVLLRQSPQKVLELWGEPKSVDDLKTLLVNYLNGKLASLPWSDVPISNEIDSIKPQILE
LNNRGILTINSQPAVNGAKSTHPVHGWGPKNGYVYQKAYLELLVTPEVAEKLVKKLENQS
EITFYAVNKTGNLQTNAPGGPNAVTWGIYPGKEVIQPTIVEKISFLAWKEEAFRLGNEWA
KCYPAESDTRKFLDEVFNNWYLVNIVHNDFHDSTGIFDLFNDL
>A0A840ZFT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum rhodinum|TrEMBL
MPSASQHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVKETSLKPAAHLTCVNATREEIDSVVQSYWDAGVRHIVALRGDPAEGVG
YTYRPHPGGYAQTCDLVAGIKRIGDFKVAVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFDNEIYLRYRDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLESDVETRRLVAAAVAAEQVLDLVDQGVEDFHFYSMNRSDLVYAICHLLGLRSQVPAK
LAAKAA
>A0A7K6H836|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malurus elegans|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDSDRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFEDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLESGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLERVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLRKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A851ALH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sula dactylatra|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETVLHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A1W1D1N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MYEKFCDVLCLEKNFITVEVNPPHGASITSIIDNIKKVNLQDKVTGFSCTDNPLAKLKMS
GVLSAIKLQQAFGKPVLATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKFSDQPD
VKGVLERDSTLLLSIIHHLNKGVDYSNKALVPAPKPIYPFAVSDASAKNMNNLKKRMIKK
LNYGARAIITQPVYNLENAKELLALFEEAKEESIRETAKEANIVLGQFPIVRAKTAHFIH
DKVPGISVPKDIIDEMNLASMDGEEKEQEVGYALSKRIFDEIMDIHGKVHLMTHNRFELC
SELIGKHHETQS
>A0A1G8XZF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catalinimonas alkaloidigena|TrEMBL
MTKVTEHIAHANGKPLFSFEILPPLKGQSIQNLFSDIEPLMEFKPKFIDVTYHREEYVYK
KRENGLLEKSVTRKRPGTVGICAALQHRFGVDAVPHLICGGFTKEETENALIDLHFLGID
NVLVLRGDPIKTEGSFCPEPGGHAYATDLLQHVANMNKGIYLDEDLEHPAPTNFCIGVAG
YPEKHFEAPSLKADFKYLKMKADLGAEYIVTQMFFDNQKYFEFVKKCREVGITIPIIPGL
KPITTMRQLTVLPSIFHIDLPDDLVEEVEKCKDNKAVKQVGIEWGIQQSKELIEFGVPCL
HYYSMSKSDAVRQIAAEVF
>A0A170PL31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MGSRLQEDFQNIHQGVYFVGTTPPKDSTTSERVDEIAEKLLERLSALDYDGMIVYDIQDE
SSRTNKPRPFPFMQTFDPCAYSRIIREKSGHPVITYKSVAQRNASDFSDWLTRAWNEFGV
RDIVLVGAPSSEGDIRLSLPEAYKVLATHEAPYHLGGVTIAERHAAKGNEHTRLLNKGKQ
GCTFFISQAVYDANATIDLLTSYAKSCAEQGVEPQRIILTFTPCGSLKTLEFMEWLGISV
PESTRQEMMAAEDPLAESIKICHNNLQHILAECLPLNLPLGLNIESLTNRKTEIDASIEL
FTLLKKTLDTGLEERRKAS
>A0A1X1JIE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLTIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLR
>A0A3B1B7F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MESQKKFQPTYSFEVFPPKTEQGAEKLRLVRDRLMQVNPLYISVTYGAGGTTRDRTIETV
TEFQEAGVSAAPHLSCIGSTKEEILDLLELYRSKGIDRIVALRGDLPSGMGAGEAGDFRY
ANELVEFIRTETGDHFFLEVAAYPEFHPQASSARADLDNFKRKVEAGANGAITQYFFNAD
AYLSFVDSCEKMGLDIPILPGIMPITNFTQLARFSDGCGTEIPRWLRSRLEGYGDDLESI
HALGQDVISKMCQRLLDEGAPGLHFYTMNQANSVLGIWKKLGLPGAELL
>I2FQ18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ustilago hordei (strain Uh4875-4)|TrEMBL
MALSNQAATSATATPSDPAHITTKIQSALSRDSPFWSFEFFPPKTTQGLANLYNRIARMR
ANLDPSWIHVTWGAGGTTGGKSLELAGRIQKGKLHPDLQLVQTEAEHLDSGPQQQHLDNV
KGGQPCEQGGLDACDVCLHLTCTNVEKSSLDETLAAAKRLGIKNILALRGDPPRGDEYWV
AADERFQHATDLVRYIRDNHGHFFCIGVAGYPEGHADYVDRDVKRDLGYLKEKQDAGAQY
IVTQLFYDVDRFLAWYKECRAIGITIPILPGIMPIQNHQSFRRMTNLCKVQIPQPILDAL
EQIKSDDAAVKEYGVSLSIHTIGRIFLESDIRGFHLCSLNLEKSIERILDGLRWKTDLGA
QAEAEAPLTAIPAHIHLEKTRNQMLCDETGAQTPKDLKVTTQEALARTLARTSASYQVPE
TTTWDEFPNGRYGDSRSPAFGEMDGYGVSLKVPPQDALRIWGHPLTLADISKIFASYLEE
RIACIPWCDAPLMSETLQIRHHLLSLNRLSEPSTTDAAQSGKGWWSVGSQPAVDGAPSTD
PTVGFGPPGGFIFQKAFVELFMSAADKDRLISRIDSLGPDAQISYFSGNAKGDFASNLGD
GEANTVTWAVFPGKEIVQSTIIERESFEAWRDEAFEIWSEWSLLFPKASASCKLIEAVKE
ARWLVTVVHHDYKDIEALWHFLAE
>R9AFX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia ichthyophaga (strain EXF-994 / CBS 113033)|TrEMBL
MKITDKLLAAEREDRLWWSFEFFPPRTAQGMTNLVDRIERMRRLGPEFIDITWHSGGRTA
ELTTELVKTCQASIGVETCMHLTCTGMPREKVINALEEAKKNGCTNVLALRGDPPRGQTE
WYPHPNGFTYAVDLVKHIKSVYGDYFEVAVAGFPEGNLQYKHSSDKALEMQYLKEKVEAG
ADLIMTQMFYDVDNFIDWCKQVRKAGITVPIVPGIMPIQTWNGFQKAVQMAQANVPESWM
QQLEAVKEDDASVRKVGTKLVSQMCKQILDANIGIRGLHLYTMNLERGPKMILQELNLIP
QTQILNPLPWRPSLTPMRRTENIRPIFWANRQKSYLSRTEMWDEFPNGRWGDSRSPAYGE
LDGWGPTINLKAEEALEIWGEPSKYDDICSLFSRFCLNDLKALPWSDQPPARETSVIDRQ
LAKMNDIGFFTINSQPAVNGARSDDKVHGWGPKGGYVYQKAYLEFFVSPDNLDKLISRIE
LNPMMTYYAVNKRGDLRTNTHSEGPNAVTWGVFPGSEIVQPTIVEAVSFMAWKDEAYELG
YQWSDMYKYGSASQQIIRQIMDTHFLVNVVHNDFKNGQDIFKPFINEFDKKTVLNDTTKN
>A0A418RSW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcales bacterium|TrEMBL
MQSQTKHPQLFSFEFYPPKTEEGAISLHVVHAQLAKLNPDFFSVTFGAGGSTRDKTLDTV
IDIQSQGVAAAPHLSCVASTKDNIRAILKNYQDKGIAKIVALRGDLPSGMLSAGEFRYAN
ELVDFIRQETGDYFQIHVAAYPEVHPQATSAAEDFKNFKRKVDAGANAAITQYFYNADAY
FYFIDNCEKNGITIPIVPGIMPITQYTQLFRFSEMCGADIPRWMRKRLEGFGDDRASVQA
FGLDLVSTLCQRLLDNGAPGLHFYTMNQSVPTLAILERLNIK
>A0A3B0XQS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKTQQKLEKHFSCEFFPPKTDKGMDKLYATAEKLKQEMNPAFFSVTFGAGGSTRETTFDA
VKKVHHSTGCEVAPHLSCIGSTKQQLGDILDSYKQQGIQRIVTLRGDIPPGETQQHGDFN
YAYQLVSFIRENYNEQFHIEVAAYPETHPQAISADKDLENFKTKIEAGANSAITQYFYNI
DSYFYFIDSCEKSGLDIPIVPGIMPIANYTSLSRFSDMCGAEIPQWLRRKLESFADDSVA
IQDFGAEFVSSMCEKLLAMGAPGLHFYTLNQSEASLRIWNNIKP
>A0A5N5V2Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium phlei DSM 43239 = CCUG 21000|TrEMBL
MTFGPCGGVRPDGQCEMRPGACSFDDVVPWTGTPVAAPPVAPPLVVTDFSCAPFDPDDVA
ATARILAPSCDAVLVGEHQNRPDFPPTLMGRLLLDAGATPWITLSCRDRNRVVLEQELRG
LHSTGVRTAMCVTGDGRGYDVRPDVTQTFDLDGPRLVALAASLGMTAAVPETPTAPPVRA
RPLRLVEKQRAGAGVAVLNHVRTPEMVAEFMAAARAAGLTIPVIAAVAVFTDSVSAAVLQ
GLPGLELDQAVVEQVLTDRDPVAAGIEAAVREARALLAIEGIAGVNLSGSASASGTRVGA
EIKAEVGRRIYPEAA
>A0A418RIN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcales bacterium|TrEMBL
MHTPEKHSQLFSFEFYPPKSPEGAISLQQVYSKLAELNPDFFSVTFGAGGSTRDKTFDTV
VDIQNQGTAAAPHLSCVASTKANIRSILKDYQDNGISKIVALRGDLPSGMMSAGEFRFAN
ELVEFIRQESGDHFEIHVAAYPEVHPQSESATSDFKNFKRKVDAGANAAITQYFYNAEAY
FYFVDKCEKSGINIPIVPGIMPITQYTQLFRFSEMCGADIPRWMRKRLESFGDDKASVQA
FGLDVVSELCQRLLDQCAPGLHFYTMNQSVPCLAILDRLKI
>A0A3B0ZKQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MDSQKQFERTFSFEFFPPRTAEAAKKLVDTRDKLATLKPRYFSVTFGAGGSTQKGTLEAV
LDIRKAGHDAAPHISCIGTEKSVIAELLNTYKDNGIKHIVALRGDMPSGSHDVGDFQHAS
QLISFIRETTGDHFHIEVAAYPELHPQSPSVQSEIKYFKEKVDAGANSALTQFFYNPDAY
YRYIDDCEKNNINIPIVPGIAPITNYTNLARFADNCGAEIPRWILKRLIDFGDDRAAIYD
FGLEVVTKLCQDLLDNGAPGLHFYTMNGAKASTALWKNLNL
>A0A8C5IJW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Junco hyemalis|TrEMBL
MVNESQQSCSGSSSSRSDGGSSSGSESSKDSSRCSTPVLDAERHERLRDKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDHMGAGGPLFIDVTWHPAGDPGSDKETSSMIIAYTAVN
YCGLETILHMTCCNQSKDDITGHLHKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVYAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRWAELQIMDGGNSSS
PAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMP
WNDDPLATETNLLKDQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLE
FFTSSEIVRALLKVLRKYELRVNYHIVNVKGENITNAPDLQPNAVTWGIFPGREIIQPTV
VDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQ
VVEDTFELLNSPTQQ
>A0A7X0FE66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sacchari|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
RFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQANDALSDLRHFKAKVDAGADAAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAEAIREFGADVV
ATLCQRLIDGGAPGLHFYTLNLAKPTTSVLARLPLAVG
>A0A525L339|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium sp|TrEMBL
MTPSDSALGPVARAGVGGTPRPNVSFEFSPPKTPEAEEALWEAIRRLEPLNPSFVSVTYG
AGGSTRDRTHRTVLRMLQETTLKPAAHLTCVEASREEVDEVIRDYWASGIRHIVALRGDP
PGQIGGAYTPREDGYRNATELTAGIRAIAPFDVTVGLYPHVHPESPSLEHDIDVLKAKID
AGASRAVTQFFFDVDGFLRFMDRVRKAGVTIPISPGIMPVTNFTGLKKMARPIGIQLPHW
LANLFEGLEKDPETRRLIAASVASEMCASLAEEGFGDFHFYTLNRPDLTYAICRVLGVRE
TPPEPKEAAA
>A0A1J8NK19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rickettsiella isopodorum|TrEMBL
MPLRQKFSFSFEVFPPKTKKGSQDLNQTRQELSQLKPNYFSVTFGAGGSLQQKSLNVVRQ
FVNDGMPATPHISCVNMTHQRLHDLLTEYKQLGIKQLLVIQGDLPSDNTPINIEFNYASE
LITAIRKMTGHYFHIIVAAYPEFHPRATSPAMDIENFKRKIEAGANSAITQFFFNSDAYF
RFIEACEKSSIRIPIIPGITPIMNYQKLMRFSTACGAEIPLWLHKHLKTYCDDPISLQEI
GIEFVTKLCHSLLQNGVKEFHFYTLNRTEPTHRIIQNLNSTYIPKGK
>A0A3B9F7P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Richelia sp|TrEMBL
MNAFRQAIEAGSFLVTAEVTPPKGGDPSHMIQMAATLKGRVHAVNITDGSRAVLRMSSLS
ASAILLQHGIEPICQMACRDRNRIGLQADLMGAYALGIRNVLALTGDPVKVGDNPEAKGV
FDLEAIRLLQTIDKLNHGFDYNEKPLINGGLDLLVGAAVDPQSRSWSGLQKRFERKVKAG
ARFFQSQLVTDFDLLDKFMNTIAAGCNIPIIAGVFLLKSAKNANFINRMVPGVNIPERII
ERLEGAKDPLEEGVKIAAEQVKAARDICRGVHIMAVKREDLVSPILDIAGIKPVIELGLE
TKVPK
>A0A3D9MM42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. BL27I4N3|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLVTLKPKFVSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLDNFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCRRLIDAKVPGLHFYTLNGAAATKAICERLAV
>A0A8H4YJI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium austroamericanum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDAEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSVEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFNGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLERLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAVYPEWEATGLEAGGRAEAVNTRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWDYPKTRQDINDLFVKHIQGELSAIPWSE
EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PANEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGSTEASPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNLIHHDY
VNRDALWEVLSS
>A0A8H5MCV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gymnopus confluens|TrEMBL
MKLIDKISSYNSLRPFYTFEFFPPRTDQGFENLLARIMRMSNLNPLAISVTWGAGGNTKE
SSLNLAEINQRNYHLDTILHLTCTNMEKGSVDEALRAAKERGIQNILALRGDPPRGKEEW
IPIDPRFQHALDLVKYIRAHPEFSSHFCLGVAAYPEGHPDHLVDEEAEMRVLMEKVDAGA
DFIITQLFYDENQFISWIKKVRNYGISVPIIPGVMPIQTYQSFVRLTKLTGSKVPDEVMS
RVDAIKHDDQLVKDYGVELAVKMIRRIMAETDAPGYHFCTLNLEKSIQRVLETLQWIDHP
QVLSNKLIEEPPFRQAAAATITPVTATNAATLGLANIPSTETEVGSGELNKADSWDDFPN
GRWGDFKSPAYGMQGPWGNSDSINTSTISEWGNPRSLEDLTAMFLKYLHSQGSSPFSSSP
ILDETKLILPHLQRLTKRGWWTIGSQPAVDGASSSDPVVGWGPQNGYVFQKCFVEFFCTE
HDLQSIELKIQEKGNGWVHYYAADSKGECRSNVPEDGRNAVTWGVFPGQELIQTTIIEQQ
SFLAWKEEAFSIWADWASFYRPDSEERQLLETIYSDCWLVNMIHHDYKRPDMLWTFIFDG
>A0A4R0J6V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella speibonae|TrEMBL
MFELICEVEPPTRPDLKKVRHQIGVMSPIADGFLIPDNHIGRATVSSVAVANEVQLMGAR
GIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVHGDDPAEGARTSQLTVRRMIEQTRETT
YPGCEPFKVGAATRLTKVPRWKAEADFLYVQVSYDLDELLRWRESVELDIPVYAGVMVLA
SAQMARNLAKLPQLQIPADLIGAVERDRDAGVDHACEQILKIRDSGAFEGVHLIPVSRYR
QVAARLERDLLQRDS
>A0A421JC48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meyerozyma sp. JA9|TrEMBL
MRISEKLQQAHSCANPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALSKAYTSGCQNILALRGDPPLD
GSDSTGDFKYAKDLICYIRKKYGDHFNIGVAAYPEGLGDESPELTLEYLKQKYDAGADFI
VTQMFYDTDNFIKWCHSVRKIGISIPIIPGIMPISTYAAFMRRAKWSKIAIPPHFLEALE
PIKEDDYLVRQKGTELVSEMCQKLIDSKAVSHLHFYTMNLERATIMILENLNLIEPVKDH
EVIGGVDLPWRKSLHPSRSKESIRPIFWQNRKYSYISRTSTWDEFPNGRWGDSRSPAFGD
IDLFAADLLRQSPKKAFDLWGCPQSFKDLSDLVVSYLKNDLKSLPWSDGPIGEDTAIIVD
KLISLNQRGFLTMNSQPSLNCIKSSDKVYGWGPKNGYVFQKQYLEFFCHRDIFGKLLQSI
EKFNQKGGESCSFLTYYAADKNGELTTNTKEDDINAVTWGVFPGEEILQPTIVERTSFLA
WKDEVYRLLAEWGKVYDSHIASDETLKKSQVKEFTHTLNEFADQFILCNIVNNNFVDDDS
VLFSLFDDIKSSEF
>A0A417GDV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM29-26|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A087DP90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium stellenboschense|TrEMBL
MHQPMFSLEVFPPKRDAPVGTIYDTLDGLQGMHPDFISVTYGHGTHADRTATARIANTIR
KEYRIPTVAHLTALYSDEAKVDEALEMFEHAGVDAVLALRGDYIEGETPVGVFEHAIDLV
RYIRARKPELKVFGACYPEGHYQAASLDQDIDYLKAKVDAGATHLISQLFYDNEDFYRFL
DKARAAGIDVPIEAGIMPINGAKSLRSMAAKNNTVVPPAVEALLEKWGSDVPTLREAGIN
YASTQITDLVAHGVDGVHLYTMNRPATTRRIWRNVRPLFTKTEE
>A0A1J7C787|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sodalis sp. TME1|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEQTLWQSIDRLSELKLTFVSVTY
GANSGERERTHSIIKDIKERTGLDAAPHLTCIDATPHELQAIAQDYWRSGIRHIVALRGD
LPPGSGRPAMYGADLVALLKKVGDFDISVAAYPEVHPEAKSAQSDLINLKKKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDTEIVPGILPVSNFRQLQRFASLTNVKVPNWMTAMFD
GLDHDLETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELTYAICHTLGVRPEIKAAP
AANRAAG
>A0A520X1P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MTALSAEETRVLKHTLREAYMEVFPTATIETRLDVLEPNSYVAVTCSPSKGVDVTLDLSE
RLANKGFKVVPHLAAKMVRNKSHLHEIIARLNDLPIISIFVPGGDAEAPLGDYSTALDLL
RDIAETDHKFTEIGVAAHPEGHPAVATDVLTGELRRKQEIANYLVTQMCFDADAVVSWLR
SIREQGVSLPAWLGIPGVADRASLLQTSMRIGVGDSLRYLKRNPRLAARLMWSNEYRPDG
LLSELAPYLADPAYDIRGHHVYCFNQVEKTEQWRHKFLEELS
>I5D223|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia hospita BS001|TrEMBL
MERLGEVAAGTPVNIAFLGSETIEQRLDAIATLARRGLQPVPILSARRLVSTEALESFLV
RANDVARIKHVFLVGGDPTAPQGPFVDSMELMSSATLERFLLKRVGIAGYPDGHPKISDD
VLWNCLHRKVVFLEAKGIEVEITTQLTLDADAVVSWVERVRQSGIQSLIRIGVPGPATVA
GLLKFASQCRVATSLGFLEKHGWQIPSLLGRVGPERFLLGLQKELGRRSLGRIALHIFPL
GDLSDAVRWFQSYCGRAS
>A0A0D6PS96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter frateurii M-2|TrEMBL
MIRSIGQVRTNLMTESSIELLPSRILELSGVLPDLDRGSRVFVTWLPGVPFADVLAACDL
LKLCGYLPVPHVAARSIRDTQHLRNICTALIERDIPRMLLIAGGADKPAGTFTDTVQVLE
TEIPAQAGIRTVYVAGHPEGHPQATEKQLEQYLLRKQELARAQGLNMQIVTQFCFDAAPI
LNWEKRLRAAGVRLPINLGVYGLTTPRTLVRYGLACGVGQSLRFMQKQRWKLHRWFTPCN
PKDLVDAIAGSIAETPDTLFHGLHFYPFGAIARTLEWRRNFSCSTYGEPS
>A0A3C1DZ48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacteriaceae bacterium|TrEMBL
MTNTEARCPERVPFSFELFPPRSDTAEHNLWDTIQHLAAVGPDFISVTYGANGSSRQSSL
HVLRYILENTSVSPLAHLTCVGSSHFEANRLVREFLDAGVTSFLALRGDPPRGAVEGDHF
LGDLGSASELVQLIHRVQTERAQYATLRSRSANGIGHIPSTRAKVRVAVAAFPNGHPRSK
RSNQDIDTLLAKQVSGATMAITQLFFHSEDYQRFVGEAVAAGVTIPILPGIMPATNPSRL
ARILELTGERRPDDLARRLEATESVDEQRAIGVEHAIDLANDVLAGGAPGLHLYPFNQHQ
AVLSVLEGVGLTAATPSTARSNIKETA
>A0A0Q9KG52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Knoellia sp. Soil729|TrEMBL
MAPRSIPALLAGKRPSVSFEFFPPKDDASEAVLWDAIRRLERVRPDFVSVTYGAGGSTQD
RTVRVTERIARETTLTPLAHLTCVGASVEDIRRVVGQYAAAGVRNILALRGDPPGDPGGA
WVAHPEGLDHATDLVALIRTLGDFTIGVAAFPDVHPSSADLDQDVEVMLKKADAGASFAV
TQMVFDADSYLRLRDRVAQHRDLPITPGLMPVTNLRQITRMTQLMGTPLPPAVVGRLEAV
SDDPAAVRAVGVQIATELAQRMLAEGAPGLHFITMNRSTATLEVYDNLGLSATAR
>A0A0D6PV79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter frateurii M-2|TrEMBL
MPAQTGPLPAISFEFFPAKTEKAAATLLENAKTLAAFGPQFMSVTYGAGGSTRDRTLATL
KDMVRETGAPLAGHLTCVGASKEEVNAVAQAYWDAGVKHIVALRGDPPPSAGGVYEPHPE
GYAGAVDLVRGLKEIAPFEISVAAYPETHPAALNPQADLEHLRAKIDAGADRALTQFFFE
AETFLRFRDRAAAIGIERPIVPGILPIGSAAQAWKFAEMCGANVPKWMRDLFDGLDETPQ
TRALIAATVADRLCQTLKAEGVEQFHFYTLNHADTASALCRLLGCRPL
>A0A6J2HWP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pipra filicauda|TrEMBL
MVNETQQSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAADL
VKHIRSEFDDYFDICVAGYPKGHPEAESYETDLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGHRVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A5D6Y6C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pythium brassicum|TrEMBL
MGKIIDSLLAAGDSGRPTVSFEFFPAKTHDGVFNLLQRVEEMALALQPTFVTLTWRSAFK
DEALWLRIGAHIQNEFQLDVLLHLTCHLPREQLKLVLARARAAGIRNILALRGDPPIGAE
RWQPVPNGLSNAVDLIRLIREEHGDYFCIACAGYAEVHTEAWNHPELPPSLEARQLDLAR
LKAKQDAGADFVITQFFFDADLLLQWVRDCRAAGITVPIVPGYLPVQNYNSFCKLTSWCK
TRVPPQVAADLARLQNDDAAVRRYGAELAVATCRRLLAAGLPSLHFYTMNLASTVTQVLD
GLALVPTRSQRGLPWQSTLRRAGSGGQGASNGGSHSPNSSSNSSSSGGGGGGGGGEQVRP
IFWSNRQSSYIARTSEWDDFPNGRWGDRTSPAYGELSEYYLAFKRPKADRKSLWGTPQRA
EDVWRVFERFVDGAIKQLPWCEQALSLESAAIRENLKWINAHGFLTINSQPRVNGAPSAD
PCFGWGGPDGYVFQKAYVEFFVAPPLLRKLLAVVAEYPQLSFHALNVRGDEHRNTPAHSV
TAVTWGVFPGQEIIQPTVVDSDSFEAWKDEAFELWKAQWASAYEKDAPASYQVIQDIYDS
YFLVNIVDNDYANDDSDIFSIFTRIITDDMSKDDLRARVLELEAKNEKMRESLAKVKSIQ
EETAKDLSDTHRELAAQREANQRLKTQMRQLKAQLALTAL
>A0A2M7SV07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG_4_10_14_0_8_um_filter_46_9|TrEMBL
MSKLSEALQSGKFVVTGEVGPPKGVSVQEMLESAKLYKGRVAAVNVTDQQSAVMRLGSLA
VCHLLKEMGIEPIFQVTCRDRNRIAIQSDLLSAYVLGIENVLCLTGDYVTLGDHPKAKPV
FDLDSVSLLQAAVQLQQGKDLAGKELDGIPKFFLGATVTPGANPLEPQIIKMEKKVKAGA
QFFQTQAVFEPRKFEEFMQTVKHLNVPVLAGIILLKSAGMARFMNKNVAGVHVPDSLIEE
MEKAENRVDTSIEIAARLINELKGLCQGVHIMPIGWEKRVPAVLGAAGL
>A0A8J3ACB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Egicoccus halophilus|TrEMBL
MSESHSVGGRPDEPGDEDTPRPTVAPIDLAGLVRNIGYEVMPFKKTEASVLQHVPKDVPL
TVTAAEGRGLDATLDLAVALARAGYRVAPHLAARLVEDHGQLRRITERLDEAGIRSLFVI
GGDAPEPHGPFSSAKELIDALDGIGFSYENLGVGGYPEGHASIPEAALDTALHQKATHAD
RIITQICFAPDTIAAWASRLEQAGVHVPIHLGVPGPVNRQKLMRISAGIGLGQSARFLQK
QQNLVWRLLVPGGYNPTRLLRRLGKTLSQTPTYVSGLHIFTFNELERTEAWRQKLLASVR
A
>A0A0F5LCJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia soli|TrEMBL
MIEDHLRASRLVADKRPDLQLSFEFFPPKTDAMEEKFWESINKLAPLGPRFVSVTYGAGG
STRERTLRMVRHITSDTGVPAAAHLTCVGASKAEINDVIRGFEAVGVNRIVALRGDPPEG
IGQPFTPHPEGYQNAADLVAGIRKLGDFDISVAAYPEKHPQSANWDEDIDNLKRKIDNGA
DRAITQMFFNNADYLRFLERARKAGISAPIVPGIQPIHSFKQISGFAARCGASIPDWLAD
RFEGLQDDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRANLVLALARLLGRRPR
>A0A8F7TLD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia mucilaginosa|TrEMBL
MTTVHPALSFELFPPRSHASCESLLHTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSARLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSDAE
LHRIGVEYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEF
A
>A0A848BFY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraclostridium bifermentans|TrEMBL
MSLLREALESGKFAITAEMAPPKGIDLSHLVECAKAVKGRVHAVNVTDFQSAVMRTTSLT
TCKLLKDEGLEPVLQVTGRDRNRIAIQGELLSAGVFGIENMLALTGDHTIVGDHPQAKPV
FDLDCVGILQTAQKLSQGTDMVGNQLKGSPEFYLGASVTPRYTPIEIQLLKMKKKINAGA
KFFQTQAVYDIDTMREFKEHTKEMNTKILAGIIPLKSPGMAKFMNENVPGIYVPDELIDR
LRSVGKENWASEGIKIAGELIQQLRDEDLCDGVHIMAIGAEENVPAILDAAKL
>A0A3S9CKI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1E.F.Ca.ET.045.02.1.1|TrEMBL
MIARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGRFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKAFMQSARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A533TPW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium sp|TrEMBL
MLVKEILNAAAKPVFSFEFFPPKKDEEWETLFKTIAALSPLNPSYVSVTYGAGGSTRSRT
HSLVTRIQKETGLTVVSHLTCICSDKEETGTILQNYRENGINNVLALRGDKPAGTESLAE
SIKDFPHAIDLVRFIKTNYPDIGVGVAGFPEGHPETPNRLLEIDYLKEKVDAGADYIVTQ
LFFDNRDYFDFVERCLIAGITVPIIPGIMPVTTRKGMIRMSELAQGARIPAPLMKKVLNA
GSDTEVASIGIEWATGQVQELIDHQIKGVHFYTLNMADATLRIFRNLQQ
>A0A369Y265|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrilyobacter sp. S5|TrEMBL
MKIKDIFKNKDTVISFEIFPPNNKFPIEKIYKTIDELAELKPDYISVTYGAGGTTQGRTV
EITNRIKNINKIETMAHLTCIGATEESINDTLKQLKNNGIKNILALRGDIPRDEIHNSHF
AYASDLVKHIKKETFFSVAGAFYPEVHFENNDLLDLFHLKTKVESGTDFLVSQLFFDNED
FYAFREKTQKLNLTVPLVAGILPVTNYKQIQKVRKLCNARIPRKFQAILDKFKDNPKALE
EAGITYATEQIIDLIASGVEGIHIYTMNKVHVTRRILENIKYIREGIREAE
>A0A1B2JBE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataella pastoris|TrEMBL
MKITEKLSSAHRREDAPPTFSFEFFTPKTAQGVQNLYDRMDRMYNLSPQFIDITWNAGGR
SSNLTCEMINTAQTVLGLETCMHLTCTNMTLEVIDEALKSAYDSGCQNILALRGDPPLDG
SESTGCFRYAKDLIKHIKEKYGDHFCIGVAAYPEGHPDEPDVDRLIEILKEKQDAGGDFM
ITQMFYDVEQFITWCKKVRDYGITIPIIPGIMPISTYASFARRAKWCQINVPSWFQKQLD
ASKDDDSEVRCLGTQLVADMCLKLVESGYVNHLHFYTMNLEKSTIMVLEKLQLIDTHNQP
VASVRDCGVESQVTVPWRRSLNPTRVNESIRPIFWSNRKFTYISRTSNWDEFPNGRWGDS
RSPAFGEVDLCDGDLIRHSPKRAVELWGKPQSIDDVIDLFVRYLQGNLSSLPWSDGETSK
EINVLLDDLLALNRQGILTINSQPCVNGLPSNHNIHGWGPSNGFVYQKQYLEFFIRSKFV
AKLISNIEELNKSYSSNFNTLTFYAVNAQGELITNSKEDDINAVTWGIFPGKEVVQPTIV
ERCSFLAWKDEAFRVFKAWSSLFKDQDQDESELLRDSKTRAILDTLHDEYFLVNIVDNNY
VQNPNVKIFDLFKTLH
>A0A2D7VNP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacter sp|TrEMBL
MATDTAADTLPDLKSGSNLERVLAAGHFAVTGELGPPKHMDTSVVDRKIDLLKGVVDAAN
VTDNQTGIVRLSSIATGIYMAQHGLEPVIQMTCRDRNRLAIQSDLMGAYIHGIRNVLCLS
GDHQSFGNHPGAKNVQDIDSMQLIRMLQEMRDKNQFQCGDEIKGGGPKLFIGGAGSPFSE
PISFRPLRIAKKMAAGVDFIQTQMIFDMDIFRQFMRRLVDLGVTEKVHILAGIGPLKSSP
MARFLNENIPGIIIPEDLLKRMDGAVQGISEDDKEARRDAWRAEGQDICIEQIEELQQME
GVSGVHIMAIEWEAAIRPIVERAGLLPRPVV
>A0A504JHH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimarina algicola|TrEMBL
MKVTEHIEQAKGKTLFSFELIPPQKGRSIQELYDNIDPLMEFDPPFIDVTTSREEFIYID
RDGLLDKKLTRMRPGTVGICASIKHKYNIDTIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFTPSKGGHAYATELVTQIIKMNQGQFLHEVIETDNKSDFCIGVAGYP
EKHMEAPSMDSDIRRLKEKVDAGADYVVTQMFFDNKRYFAFVEKARAAGIEVPIIPGIKP
VAVKRHLQLLPQVFKLDMPDELVKEIENCTSNADVRQVGIEFAIQQSKELMEYGVPVLHY
YSMGKSDNIKKIAEAVF
>A0A261QUM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella genomosp. 7|TrEMBL
MTASTTAALSLEFFPPRDIAAQERLVRAAKQMLAMQPRYVSVTFGAGGSTRAGTADTVRM
LQNLGCDAAPHLSCIGATRDSLRDILAAYREQGVRRLVALRGDLPSGMGGDPGELRYAAD
LVAFIRAQTGDTFHIEVAAYPEMHPQAASPSVDLDHFVAKVNAGADAAITQYFFNADAYF
DFVDRAQAKGVKIPIVPGIMPITNHNQLVRFSEMCGAEIPRWIRLRLAEFGDDKASIRAF
GVDVVGELCQTLLDNGAPGLHFYTLNHAEAPLAIWRELDLPA
>A0A520T5U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|alpha proteobacterium HIMB59|TrEMBL
MIKEKIISLIDGFTIELNPKVRHKINTIPLEKKNNVYITYLPDASENDILETIEFVSKNN
LTPITHLPARTMKNLDHVRQFLSQVRERTDSKKILVIGGGGNQLGQITSSLEILNSGLLE
ENNFNEIGIAGHPEGSPDISQETIDNFLNDKFELTKTKGLNLELVTQFFFNAAPFINWCE
ELTKKKITIPVRVGFPGPASFKTLLNFGLMSGVGNSINFLKKNSSKVSDLLTKTSNDEML
ISLAEFANKNSPLKSFHCFPFGGFEKTCLWLNELQKGEFTIENQQLKLHKKIF
>A0A2U2DMF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium album|TrEMBL
MSHSLLRSADLAKLHFSFEFFPPKSEEMEGQLWATIDDLAGWRPEFVSVTYGAGGSTRAP
TLSTVRRLLAETALPTASHFTCVGASRDEVHQVVEDFRAAGVRHFVALRGDPAGGVGAAY
QPHPGGYANAAELVAGLRSIDDFEISVSAYPEKHPESRDTAADIDMLKRKVDNGANRALT
QFFFDNDVFERYLERVRAAGITIPIVPGIMPIQNLTQLKRFAGACGTTVPARLDERFEGL
DDKPAERAAVAADVAAEQMADLVRRGIHEFHVYSMNRAPLVNETFARLGLTRKVAETTGA
AA
>A0A381Q3K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKIKDILTKTRPVSFEFFPPRQAEGIPAVLETLDELKQYLPDFVSVTYGAGGSTRAFTEE
ITFEIKRNTDVEVMAHLTCVGQNKEELDEVLSRLREEGVENIIALRGDPPKGTTEFVPVE
GGFQHATDLLHHVVSNYKFGVAAACYPEGHTESVDLDADLKYVKMKVENGAEFLVTQLFY
DNRFYFDFVERARAEGIEVPIIPGVLPVLNSAQVRRFTTLSGSKIPLDLDKLLDKYADSD
HSARDMGVEYATAQVRELWDSGVPGVHFYVLNRSYSVSRILDNLQIAGHQRQD
>A0A382G3P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MNFSLEIGLKTNLSNLPKVKDVYITLLPGEDFRQVAEKAKELANLSFNPVPHFPARSIKN
LDILKDYVMRCKDGGVKQALVIGGSAQPVGDFHCSLQLLETGLFEGFRIGIAGHPDGSPD
ISDSDLEKAMKDKKPYADYIVTQWLMEPDPIIKFVSKQSIPVHVGITGPMKVSGLLKFAN
TVGAKNSINFIKSNLGKTFDLLRPKDP
>A0A381UKC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKISEKIANYKAQGKTFYSFEFFPPKTDFGMDNLYSRIDRMASLQPAYIDITWGAGGSTS
NKTLEMCKTIQKYFGLEVMMHLTCTNMQVSSIKKVLIEAEKNDLSNILALRGDPPEGSSS
WEQHEDGFHHGIDLVRYIRKEFGDHFFLGVGGYPDGHQEQSDLDADISFLKEKVEAGADI
VVTQLFYDIEKFLFFRDKCIKAGIKVPIIPGIMPIHNYARFLKFTQFCQVSVPDSVTVQL
EPIKYDDSSVINYGIDQASGMCQKLIENGVPGIHFYTLNLENSVSAILKSLGLVSSQGII
KELPWRQSTSGSRKTSEDVRPIYWSNRPVSYLTRTEIWDDFPNGRWGDIKSPTFGELNQY
HAIRAGSKSDKIRAKRKKIWGEPKTIKDITDVFVSFCKGKINSLPWCEMPLAQESKQISD
DLLKLNEMGYFTINSQPKINGLPSEDAEVGWGGSGGRIYQKAYLEFFTSKDKLDRLLKSI
GSKENISYEAINISGDLITNLPENNAMAVTWGVFPNKEIIQPTIVDTRSFLIWKDEAFSL
WMNDWASIYEPKSGSYKLIKEIYDTYYLVNIVDNDYVDGELIQQMLIF
>A0A8E0KFI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O119:H4 str. 03-3458|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A382H4T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MMESLWHSIIRLAPLGPRFVSVTYGAGGGTRVRTHSIVSRIRAETELEPAAHLTCVGATI
AEVDAIARGYYEEGVKHVVALRGDPAKGDER
>A0A383E7A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKYFKDALGTKDFVITSEIFLKPETDANSIKIQADVLRDYVDAILLTDNQSGQLHMSSLV
AGVLLLDAKIDPIIQLSCRNRNRISLLGDLLGCAALGMTNLSLIRGDRVPDEFQPRPKAI
MDITATELIRMANKMKVDDRIKSVENFLLGGVVTPHGPKPGWQAKNITEKIDAGAQF
>A0A8I2YQB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boletus reticuloceps|TrEMBL
MKLSDKIAAHASTQPFYTFEFFPPRTDQVGYMPKLVRFLLNGRQGFDNLISRISRLSLLH
PIAISVTWGAGGSTRGRSLDLAGLTQSEYSIDTILHLTCTNMLPGMVEDALREAKARGIQ
NILALRGDPPLGQEHWTPIDSRFTSALDLVKYIRSSEEYSSHFCIGVAAYPEGHSENDIN
EDDAINILKQKVDAGAEFIVTQLFYDADRFIEWTRKVRSRGITTPIISGVMPIQTYASFL
RVVKLCGAQVPSNIMVDLYTIRHDDQLVKDYGVRLTVDIIRRITGSGLVSGIHFCTLNLE
KSVQAVLESLGWAGGSPIVKNKLIAGSPLPSIRPSLPSSDLVVTPSLATTTAANALTSKP
SLEVEPPGCGELNNAATWDEFPNGRFGDYKSPAFGMQDQWGGLGINVHAVQSHWGNPTRT
EDLTKLFLDYLDSNTSSTPFSASPLSPESGTILEHLKKLTRKGLWTVCSQPAIDNADSTD
DVFGWGPKGGYVFQKGFVEFFAEENIVCQIEKRIEMEGKGWIHFFAANSQVGCGTRRELM
A
>A0A6A8LJQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus velezensis|TrEMBL
MGLLQDLKERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIADLGADITGINCRLGPYHMIEALTEVPIFRDTYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTDKEVKIRREEEVI
SVRNERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAATELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKQKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A6A6DDD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zopfia rhizophila CBS 207.26|TrEMBL
MEKVTDKINSLPNDAHYFSLEFFPPKTTMGFVNLQNRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRKLGLTTCLHLTCTNMSRSLIDDALDQAKVLGIRNILALRGDAPRSEE
YRDEAQLLEGDSNNDFTWAIDLVKYIRKQYGDYFCIGVAAYPEGHSDESHPEHQDPLFDL
PYLVEKTKAGADFIMTQLFFDVEAFDKFETMLREHESGVFKTIPIIPGLMPIQSYQILRR
TTQLSHAKLPADMLTRLDKVKGDDELVKKVGVEILDEIVEHIKTRPSTGRRGFHFYTLNL
EKAVSHILEDCHLIPPMFMEDEEAVTASSSPGNLSPPNGAMTKDRRRLSSVNSGPHNRVV
VSQPSKSSHPSFEAPEDEAGIPKGPFNTRANTLAISEGEGSLGREATWDDFPNGRWGDAR
SPAFGEIDGYGPTLHVSTPQALRLWGHPVNTSDISTIFRKHISGELEAIPWSEQGLNPET
SIIRDELLALNSKGWWSVASQPAINGVKSSDPVFGWGPKNGFVFQKPFVEFFIPSSDWAK
LKPRLESNPQITYFAGNAKGEFEASAEESVNPVTWGTFAAKEIITPTIIEKVSFWSWCEE
AFSIWREWQRIYMPKSETSKLIERTREDVWLVNVIWGDFVDGKGLWEFLMRE
>A0A382ATK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MPTKSTRLNQNKFIYTSELTPPKGIDLSKLINTASNLNMIDAFNITDNHNSKMTMAPIGL
ARKLIENNIEPIYQITCRDRNSIAIQSDLLAAYSLGVNNILCMSGESVKYGDHPNAKDVF
ELSSEELIETITKLNNGYDYANNKLDSVTNFNIGAVVNPGSNTIEKELKKFENKIKNGAT
FFQTQAIFDPKTLNNIIQIKQNKNIKILAGYIPIKSVKMANYLNNKVPGIQVPENIINLM
KKTDDPQKTCIEISKEIISEIKAIKGIDGVHIMALGWEHLIPKMI
>A0A0S6XRY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fungal sp. (strain No.11243)|TrEMBL
MHISPKLRQSAQEKKPTFSFEFFPPKTAQGVQNLYDRMDRMHAFGPTFVDVTWGAGGRLS
QLTCEMVKVAQSVYGLETCMHLTCTDMPKSKIDEALKEAYNAGCTNILALRGDPPREKEK
WEVVSGGFRYAKDLIKYIKDTYGDHFDIGVAGYPEGCDDHRDTELLVKHLKEKIDAGGTF
VVTQMFYNADIFIDWVKQCRAAGIDVPIVPGIMPIQTHSAFLRRANWTQCDVPPHWTKAL
EPVKNDDAAVREVGKGLIAELCRKLMDAGIYHLHFYTMNLAQSTKMVLDELQIMPHPESP
IEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDR
YGIGLKGTNEVHRKVWGHPTKLRDICDLFTKYIQGKVDSLPWSESPISSEADVLTADLID
LNRRGLLTINSQPPVDGAKSNHPIYGWGPRNGYVYQKAYLEVLVSPELVAELITRIEREP
EITYFAVNDEGDLKTNAEPDSGPNALTWGVFPGKEIVQPTIVETVSFLAWKDEFFQLGHE
WSSCYDNDDIGRYLISGMMQSWYLVNIVHNDFRRERGIFPLFDGLSVPDLDQTLEITPDV
LEQYKKTRRISLTNGHTMPNGNHASPKPETNGLKN
>A0A5B9FUF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium alkalisoli|TrEMBL
MKVTEHIENANGKTLFSFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYTFKE
LPSGLLEKKVVKKRPGTVGICSAIQNKYGVDAIPHILCGGFTKEDTENFLIDLDFLGIEN
VVALRGDAVKSEIYFKPEKEGNEYASELVTQIVNLNKGIYLDDDLLNTSATDFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGASYIVTQMFFDNKKFFDFVAKCRKEGITVPIIPGLK
PLSTKKQLNQIPHRFKVDLPDELIMEIVKAKDNDAVRQIGIEWCIAQSKELVAAGIPVLH
YYSMGKSDNIKAIGKEVF
>A0A3M0ZQ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MTHKELTLKEIYQTDKKIVSLEFFPPRNEDDLPSTFSLMESLAQYPIGFMSVTYGAMGNT
RSLTREMVSFIHHRLQVPSVAHLTCVNHSVSDIDNILDGLAAWGIKNVLALRGDPPKGQK
GFVPHPEGFSSALELTQHINQRGEFSVAVAGYPEVHPDADSPQDDIEYLAKKVRAGADLV
ITQLFFSPEVYFSFVEKARGLGITVPIVPGIMPIRNLKQLDKIVRMCGATIPPDLRKALG
ELQGRSKEIERFGIQYGTQLCQDLLKGGAPGIHFFTLNRSRQVQEIIRNLEDWIRS
>X5XFN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSHC412B00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTIKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHKDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A5P8JGN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus kondratievae|TrEMBL
MTTPAVSFEFYPPRNLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYKLNVAAHLTCVDATREETMQIVQDYAVAGVHEIVALRGDAPQGQARFIPHAEGFANSV
ELISAIAERGDMTIRCGAYPEPHPESPDTAADVAWLKRKVEAGASSAMTQFFFEADTFFR
FRDACVSAGIEAPIIPGILPIQSWSGTRRFAERCGTSVPQWAEEAFAASGKEGEAALALD
LCVKLCERLVEGGVDRLHFYTLNKPELVLKVCAALGIKPKDEVPQVA
>A0A0P7HC36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Edens01|TrEMBL
MDPTAALLDDFSLEMTGKDVPALREAQDALPSGTRVNVTFLGNEDLPMRLAAAAAVKAAG
HVPVPHISARRLGSAAELEKFLGALAEAGAVENVFAVAGDPAEPMGPYADSLAVIASGLP
AAHGARHISISGYPEGHPDIDNQTLWSALEQKLAAIRDQGLDASIITQFGFDTAPVLAWL
EELRSRGIDAPVRIGVPGPAGVKRLLGYARRFGVGTSASIAHKYGFSLTNLLGTAGPDRF
LTELAAEHDPGRHGVVKLHFYTFGGLRPTAEWVRSFRGY
>A0A0N7HIY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Celeribacter marinus|TrEMBL
MTAAPNISFEFFPPKNIEACFSLFETVQALEGMNPGFVSVTYGAGGTTRELTHDAVALLH
RKYGWNVAAHLTCVNATRAETLAIAESYKAVGVNEIVALRGDPPKDAGKFTPAKDGFANS
VELIAALKETGNFKIRVGAYPDPHPDASDENADITWLKKKFEAGADSAITQFFFAPETFF
RFRDRCADAGITGKIIPGILPITSWKGVQKFAASCGTPLPAHYAEAFEATDDARKLSIEL
CTQLCQSLINEGVEDLHFYTLNRPHLSKAICANLGVAGA
>A0A3D2A605|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp|TrEMBL
MSKPDFSFEFFPAKTEQGGQKLLNTYDELNKLAPSYFSVTYGAGGSTRSRTLDIVQTLCA
RGDTDIAPHMSCIGDDKVEIAGLLDHYKALGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREYSGEHFRIEVAAYPEMHPQARSFEFDVDNLVNKYQAGANAAITQFFYNADSYLYLR
DTLEKRGIDTVAQPLIAGIMPITNSSNLIRFADSCGADIPRYVRKRLADFGDDSKSIREF
GFDVVYRLCERLMSEGVPAMHFYSMNKVEPNKRLVEALGLTV
>A0A238Y5X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloechinothrix alba|TrEMBL
MIVSGSGLVEALRAGRFVVTAELGPPRGADTDVVRKKGRALRGWVDAVNITDNQGGFVRL
SSLAGSLVLLDEGVDPVMQLTARDRNRIALQSDLVSAAALGVRNVLLLSGDHPSYGDHPD
AKPVFDLDSTQMVWTARNLRDHGQLLSGRSLDPPPDLHIGAVENPFAPPVGFRARRLAKK
VRAGAEYVQTQLVFDVGAFAGWMAEVRDLGLHERAHIIAGIGPIVSPQALEHMRTKVPGV
HVPDAVATRLLRAGTEGFTEEALRVCAESIHRIRAIEGVSGIHLMAFGREHLIPEIVDRS
GLDRSRFDMNACGSRERSADAG
>A0A523QLY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium|TrEMBL
MKAGSNLEKILESGQFAVTAELGPPKGADAEVVRKKGNLLGDYADAINITDNQTAIVRMS
SIACGVILTQLNLEPVIQMVCRDRNRLAIQSDILGASALGIKNVLCLSGDHQKFGNHPQA
KNVYDIDAVHLIQALKRMRDEKKLLEGDELTIEP
>A0A317ENP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter yonginense|TrEMBL
MKITDHIINAKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADHSFIPTKGGHCYATDLIQHIKNHNDGKFLHEDIETFKSDFCIGVAGYP
EKHFEAPNLNADFKYLKQKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPDELTDALSHAKSNAEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKRIAKAIF
>A0A6I5ZXN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. JZ18|TrEMBL
MTAVADARAASAPADGRAPVDGHAPATRAARRRAPAAALDRPTVSFELFPPRDVDAAPRL
WATVRELEAAEPDFVSVTYGASGKTRETTRALVTRLLRETTLNPIAHLTCVGTSRAEVAA
VVEEFLDEGVRAFLALRGDPPAGQADWQPHPEGVATAAELVALLREVEQRRCAGSPAQAV
RARVRPLSLAVAAFPRGNQATGGTRQQDVQALLAKQEAGADFAITQVFFDAEAYLGLVAE
ARRAGVTIPIVPGIIPTTDPARLLRVQELTGVPVPRTLLDLLGSVDDPLERHRRGIRAGV
DLVRAVLDGGAPGVHVYTFNKHEAALDLLDGADLRGGRPAAAVPTTSTEPAGDLAVGPTP
TPAR
>B8FY41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfitobacterium hafniense (strain DSM 10664 / DCB-2)|TrEMBL
MENRFKQSLLDPNTLSVTWELVPGRGAREKAQESALLAAEQAAKGGKVHALTITDNPGGN
PAILADYLGQEILKLGIEPLVHFTCKDKNRNQMESQLYALDRAEVRSLLVMTGDYTVSGF
KGRPKPVFDLDPTHTLELIAQMNEGLGIPGPKGMSYHQPSDFFAGAAVSPFKGTEAEQMV
QYYKLKKKVTSGAQFIVTQLGYDARKIHEVLQFMKLNDLNVPLVGNIYILPFGAAKIMNQ
NQLPGCVVTDKLLAEIDKERTAEDKGVSARLLRAAKMYALMKGMGFAGVHIGGHNIKYEQ
VEYVIEKGEELSKDWLALVPEFDYPMPNGFYYYEKDPKTGLNTTTPVNRKNLPLDAPVGV
AYSGMRLMHSMLFTPGKNFFPVMRKIYKGRKDNRKHGLEHLAKVITNDCKDCGDCAMFEL
AYLCPMSQCPKNQRNGACGGSYQGWCEVYPNQKQCIYVRAYARLKKYDEEGDLDSHHIPP
ANWDLYQTSSWSNFFLGRDHSGKILGIPTPEEEAKAKGADPAK
>A0A7J2QYG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon|TrEMBL
MKKKNKRRREVKMVKRKAFSNLMKELESGKFVFTGELEPTKMYDLSTVLHSAEEMKKTGK
IVAANVTDGPQGDAYTCSMVPSYLVQEKVGLEAVWQMTVRDRNRIALFGDVVGGAILGLK
NILTLTGDHTALGDNKRARPVYDIDSTQFIDLVSKIIDDGNDLEGKEIEGGPIEMNIGCA
ANPNARPPYLEPEILKVGRKVEAGVDFIQTQTAFDIDEA
>A0A8H7U5D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Postia placenta|TrEMBL
MKLCQKIAGYKDARPFFTFEFFPPKTDQGFDNLLPRISRLVSLNPLAVNITWGAGGTTKD
RSLELAGITQTDHGVDTILHLTCTNMKQGLVDDVLRDAKARGIQNILALRGDPPRGEEYW
IPTDPRFTHGADLVSYIKSSPEFSSDFCVGVAAYPDGHPDRETDEDGELEHLKRKVDAGA
DFIITQLFYDVDTFLQWVKRVRQKGIQVPIIPGIMPIQTYASFLRMTKLCGTRVPHSLMS
DLVPLRHDDSKVKDYGVDLAVEMIRKLTTDGDIRGVHLCTLNLEKSVTRVLEGLSWVGGS
LKPANRLIAMLQDASIGPDANLIITPHNATDSAAISLAAAGQGPDGEAGKGELNNAASWD
DFPNGRFGDFKSPAYGETDLWGSSIMSRNQALEQWGHPKTLDDLTTMFLRHLHSKIATTP
FSPTPLSPESLMIIQHLERLTRRGWWTVGSQPAINGASSSDEVVGWGPRGGYVYQKCFVE
FFLERADLERIERKIRDEGHGWVDYFAGNVQGECRTTVPEGGRNAVTWGVFPGQEIAQST
IIERESFLSWKDEAFSIWAEWASFYPPDSQERRLLESIRAERWLVSVVHHDYTDPSALWT
FLLKGDPVL
>A0A1I0A6T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus homiensis|TrEMBL
MARTTPKISFEFFPPKTLDASFRLWETARALAPLSPDFVSVTYGAGGTTRKLTHEAVTTI
NRHYKLNVAAHLTCVEATRAETMDIVQSYADAGIREIVALRGDAPKGQDRFSQHPDGFAN
SIELIEAIAARGDMTIRAGAYPEPHPDSADTDADVAWLKRKIDAGASSAITQFFFDAETF
FRFRDKCVAAGIDAPILPGILPIQGWAGAKRFAASCGTSVPAWAEQAFAKAVAQGPEAER
ALATDICVDLCEKLIDGGVDRLHFYTLNRPEMTQQVCEALGVRAHHLDAVA
>A0A2K6K1V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhinopithecus bieti|TrEMBL
MDHRKARVLPAGHYCPSLGIWVSQAGSMRFSVPPSISRNLAMVNEARGNGSPNPCLEGSA
SSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSIMIASTAVNYCGLETILHMTCCCQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTNMGITCPIIPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDTLELLNRPTQNERETETP
>A0A1I3AZC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus aminovorans|TrEMBL
MTTPAISFEFFPPKTLEQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHDAVTALAG
HYGLNVAAHLTCVDATCEETLQIVADYAAAGVHEIVALRGDAPQGHERFTAHPKGFASSV
ELIEAIAARGDMTIRCGAYPEPHPESADTAADVAWLKRKVDAGATSAMTQFFFDADTFFR
FRDACAAAGVAAPIIPGILPIQSWAGTRRFAERCGTSVPQWAEAAFAAAGPQGEADLAQE
ICVKLCEQLVAGGVDRLHFYTLNKPDLVLKVCAGLGIHPKGEFSRVA
>A0A257R8D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiphilium sp. 20-67-58|TrEMBL
MSHTPPRAVLERWLSGPRIDPLPARMPRAPAPAISFEFFPPKTEALETQLWACIRRLESL
APRFVSITYGAGGSTQERTHATVTRLVRETTLVPAAHLTCVGASRGEVDDVARRYWDAGV
RHIVALRGDPPGGSAYAPHPEGYAYAADLVAGLRRVADFEISVAAYPETHTQAASPQADL
DNLKRKLDAGATRAISQVFFETGHFLDFLDRALAAGITAPIIPGIMPVSNFGQAKRISEM
AGTHVPAWMGEMFDGLDDDAETRKMVAASIAAEQVRTLQANGIDEFHFYTLNRADLTYAI
ARILGVKPAR
>C4Y415|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clavispora lusitaniae (strain ATCC 42720)|TrEMBL
MKITDKLQQAHSCKVGGSAPPATFSFEFFVPKTSQGLQNLYDRMDRMYDLNPIFIDITWN
AGGRSSTLTNEMVYTAQSTLGLETCMHLTCTNMPVSLIDEALEKAFKSGCQNILALRGDP
PLDGSESTGDFKYAKDLIVYIRKRYGDHFNIGVAAYPEGHPEEQNSPNLLKYLKEKVDAG
ADFIITQMFYDVDNFIAWCAKLRELGITIPIIPGIMPISTYSAFIRRANWSQVAIPQHFL
DALNPIKEDDYAIREVGTQLVSEMCQKLIDSGYVNHLHFYTMNLERSTVMILEKLNLVES
IKDNDAVVEILPWRKSLNPSRSKESIRPIFWQNRKYSYISRTSGWDEFPNGRWGDSRSPA
FGDIDLSASELLRQSPKRAYELWGCPQTLNDLSDIIVSYLNNEVKALPWSDGPIGEDTTV
LKDALIALNRKGLFTLNSQPALSAVRSNDKLYGWGPKNGFVYQKQYLEFLVRKDKLKELL
DIVEKHNAKDTYGLITYYAVDKSGNLHTNSKNDDINAVTWGVFPGEEILQPTIVEKVSFL
AWKDEVYSLLDEWITIFHSKAITDIVPEDKINKFDDLIKSFGENFVLCNFVNNDFTSDNN
VMFNLLNSLSGSCL
>R6BFL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. CAG:604|TrEMBL
MNITEFLNNGDQEKGFSFEVLPPLKGNSTAALFRTIDALKEFNPRFINITTHHSEFVYKE
LDNGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHVICSGASKEDIEYELLDLQFLGISN
LLVLRGDKAKDDRQFTPTANGHTHATDLLKQVNQFNDGFFMDGTPIKHPGEKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNQKFYDFVEKARKMGITIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDEDAKELGIEWTTAQVKDLFEHGYNNVH
FFTVSAVDSVKQIAKTLF
>A0A7C7ALE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierellia bacterium|TrEMBL
MYIRDIFKKKNFVFSFEIFPPKPTSSINTIYKTLEALSDLRPDYISVTYGAGGGSNYNKT
KEISSLIKNKYGIEALAHLTCISSTKEDIRRTLEELKEEGIKNILALRGDIPVDEAVRGD
FKYASDLAEYIMSIHKFDLGGTCYPEGHYSCKNLEEDVKNLKYKIDAGVTHLTSQLFFDN
NLFYNFLDLAAKYNINVPIQAGIMPITNLKQAEKVSGLSGSKVPEKLLNALEKFQDDKDA
MADAGIAYATEQIVELMAAGIDGVHLYTMNNPYVARKTHDNIISMIHAINRKPKTRY
>G7SR66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blattabacterium sp. (Mastotermes darwiniensis) str. MADAR|TrEMBL
MKVTDHIAKAKKSLFSFEILPPLRGHDIKDIFSTLDPLMEFNPPFIDVTYHREEFFYVEK
ENGLLQRRIISRRPGTVGICAAIMNKYGIDAVPHLICGGFNKQMTENALIDLNFLGINNV
LVLRGDPLKSEKSFFAKKDGHKYAVELVEQVQNLNIGKYLDKTFERKDSPLFDFCIGIAG
YPEKHLEAPNMESDLFFLKKKVEAGANYIVTQMFFDNKKYFSFVKKCRSKGIFVPIIPGI
KPISSKRQLNSLPSRFSLNIPNELVKEIEKAKDKKIISHIGIEWAIQQSKELKNSGVEVI
HYYTMDKPENIYKIVQAVY
>A0A6P4XEN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panthera pardus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEANSGRFSVPPSISISHLTLPLRVLAACPLTLLPSTP
CSRNPAMVNEPRGDGGPTSRSEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRMES
GDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIAST
AVNYCGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYA
ADLVRHIRSEFGDYFDVCVAGVPCPGPSVPTPSAGRRTCVPSSGPPDQRVTSTAPRSGTS
SPTAAAFGELKDYYLFYLTSKSPREELLKMWGEELTGEESVFEVFACYLSGEPNQNGYKV
TCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQK
AYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREII
QPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDN
CLWQVVEDTFELLNRPGPEQETETL
>G8BRG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5)|TrEMBL
MSIRELYNMRTSPSVSLEFFPPKTEAGKRNLLERVNRMSALDPLFVTVTWGAGGTTADKT
IQLAILAKQTLNLNVCIHLTCTNMDKNILDEALSKCKSAGIRNILALRGDPPIEHEWSNE
MNVDGKREFNYAIDLVKYIRESYDDYFCIGVAAYPEGHCEGELEDSSFSPFKDLPYLKEK
IDAGADFVITQLFYDAQKFLDFEKLFRTHISTEVPLIPGLMPINSYSLFNRAAKLSHASI
PQHILDKFQSEIQYDDNAVKSIGVKIIIDIIEEIYQKTNGRIKNFHFYTLNLEKATAHIV
ADCPLLSHILDDEHDNIAMSLQSDVVISVDDNESEVHNESSFHQKRRRHSSNTEMSRPQV
IDKNITNVVASLPSRKVLISISQGSGTLGRDATWDEFPNGRFGDSRSPAYGEIDGYGPTL
KVGNKKAYNIWGAPTRVSDLKSIFIKYLEGSIDVLPWCDLGLSPETALIQEELIQLNQRG
YLTLASQPATNAAPSTDKIFGWGPASGYVYQKAFIEMFIQKQQWESVLKPKLESYQQGKF
SYYVGDSTGKFDTNLPAHSSSVVTWGIFPNSPVVQTTIVEEESFKAWRDEAFCIWLEWAK
LFLSNNPANTFLKQVHQDYYLLSIVHHDFGDVDELWEMLLE
>A0A660YBC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MKTKSNLERVLKAGHFAVTAELGPPRGADPEAVRKKAKILKGYADAFNVTDGQTAIVRMA
SWAACLVAKEEGLDPIVQMTCRDRNRIALQMDVLGVAALGINNILCLSGDHMSFGDHPGA
KGVYDIDSVQLVKMVK
>A0A2T0AJK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosporidium toruloides|TrEMBL
MVKISDKIKKAEREGRPWWSFEFFPPKTPEGWVNLYDRIERMQQLGPIFVDITWGAGGST
SEATTNFVKTAHSELGLETCMHLTCTNMPVEMVDKALKATYDSGCRNILALRGDPPRGVE
EWKPTEGGFNHAIDLVKHIRKNYGDYFCIGVAGFPEGHPQSESPEAEIRHFKKKVDAGAD
IVFTQMFYDAEVFIDWGRRLRAAGITIPIVPGIMPIQTFAAFKRRTDFAGTIVPKELWDL
LEPIKDDDAKVREVGTKYVADMCRKILNADLGIHGIHCYTMNLSRGTEMLLEEMQFVPTA
DRVKPLPWRLSLTQKRRAETTRPIFWSNRQKSYITRTRDWDEFPNGRWGDASSPAFGDVD
ALLLALPHKPQDAIKLWGKPHSLGNITALFARFCRGDLKSLPWSDQPAAKETTRIAEQLA
RINELGFLTINSQPRVDGAPSEDPAVGWGPIRGYVYQKAYLEFFCPPELVEPLLELLGDT
PSVTYHAVNKQGDFRSNTAPGPNAVTWGVFPGAEVIQPTVVDSTAFQAWKDEAYELGWQW
AQLYKETAPETYEVISRIFSEFHLVNIVFNDYRNTDEDAIFKPFFELAHRKGLSVANGH
>A0A1F6FZQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kaiserbacteria bacterium RIFCSPLOWO2_12_FULL_53_8|TrEMBL
MKVTDLIKNSSVPFTSIEIIPPRKGTSMETLFAELEVLMRYKPAFMSVTSHAHERSVEEV
DGKKVERMKHKRLDTNAICIAAQSRLGVEPTPHLICRGFTKDETEDVLLTLHFHGIENVL
ALRGDGPLADAQTAASFVNEHASDLVEQIERMNDGVYLDPVERAEKTDFCIGVAGYPEKH
FEAPDMETDLAYLKKKVDAGAHFIITQMFFDNEAFYRFRDDVARLGIQVPVIPGIKPLYK
KQHLEVLPRIFYTKIPQSVQDSINRFDKEEDIHRAGIDSTIAQCKDLLAHGVPGIHFYSM
SVAKPTSEVLNGLMA
>A0A1H4ZAK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium GAS188|TrEMBL
MTQTKLSQAKPAKQANVPVSRLPGSNGVSVSFEFFPPKTPEMETALWEAIDRLAPLSPAF
VSVTYGAGGSTRERTHATVKRMIDETQLKPAAHLTCVAASRSEVNAIIRDYWAAGVRHIV
ALRGDPAGGAGARYEPHPEGYHWSTDLVTAVKAIGDFEVSVGAYPERHPESPTLFADVEM
LKRKVDAGADRAITQFFFDNDVYFRYLDVAQAAGITIPIVPGIVPVQNFKQTANFAKRTG
ASVPDWFAERFAGLDDDVATRRLVAAAVCAEQVLDLIDRGVTHIHFYTMNRADLVYAICH
LIGLRPALASDGTIEVAAA
>A0A0R0AB26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas pictorum JCM 9942|TrEMBL
MTAISFEFYPPKTDDQRAQLDRTAARLKTYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLQAAPHLSCVGGTREEIRELLKLYRAIGVKRIVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQASCALADLRHFKTKIDAGADAAITQYFYNADAYFHFVEA
VRKLGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWISKRMQAFGDDAESVRTFGADVV
AALCERLIAAGVPSLHFYTLNLARPTQAVLRRLGHA
>A0A1H5DGD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiangella alba|TrEMBL
MTTVLDRLAGRRPVFSVEFFPPRDDADETVLWTAVRQLEPLDPAFVSVTYGAGGSSRERT
IRTTGRIRRETTLTPVAHLAGVGHSRAELRNVVGWYAENGIRNVLAIRGDPPGGPAAEWV
AHPDGVTYADEMVSLIGGLGAFCVGVAAFPHGHPESPDLETDVRRLLGKVRRGAHFAVAQ
LCFEPDYFLRLRDRLAALGCDVPLLPGVMPLTTRRTLEKSVELSGVSAPAAVADRLARYD
DDPAGFRAEGIDLTTSMCDRLLAEGVQGLHFYTLNRSTATRELVRRLDLGTRDRTHGDAS
IPVRSVRPATGQVRDLPPCRAAAEPRS
>A0A5D2BG23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium darwinii|TrEMBL
MKVIDKIQSFSQGQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DALVKNCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGAFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A662U9G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoprotei archaeon|TrEMBL
MAGRVVVRKIYSKLMENLLSGKFVYTAEIEAGKTTNLEEIVEKGRMLKNYVTAINVTDNP
GACAHMNPLIPSYVIQRDVGVESVYQITCRDRNRLAIISDLLAAAALGIRNVLVITGDHV
IFGDNPEAKPVFDLDSATLVYLIRKMVDEGVDLAGNKIEGEVKFHVGIAANPNAVPLELE
ILKIARKVRLGIDFIQTQCVFDIDVAKEFLREVRKFNIPVLIGICPVRSIGMMKWYIKEC
PGGIKIPADMQERLIAARKQKGKKAVLEKSIEISAELIKELRKTTNAAGVHIMAIGFEHV
IPKIIEHSS
>A0A7W1L3N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MRDDLMLSAGDKLKLLRINSFVGEASLDFLSAAATAAVEQSFEKGQLVYAKDEAATAFYV
LAEGTVGHPEVQRSDASASQINTPGQMFGFAASQLDRRTLSARCEAPTRVLALDFESFLE
LCRGHGYAELPSRLAFAHKGYERDVLGRSGWISVRNVCKSFEVGEGQAALLDDCSFEVRP
GELWALFGPKGRGKTVLLNLIAGFERVNDGVILVDGEVTNRPGMRPLHGPEHVVGYRTAI
HVLRTTVAGYLQGGEEKSEKLRLLCEQLGFAPYMASRLRDVPRDVARRVEILRAFLRDPY
VVLDEPTRGLEGDDKAALTAFVLQAHSLLPKTMLFATEDIDEAIFIADQVLVMTPAGAKK
LPVAVDVRRPRGADQRELPEFTRAKQRVLDALEKAESVAPLREGFAIEVDEALPARRLPN
VANALKEALHEGRFFWTIEFIPSVDKVLHDALHKLGGTAEIMRQEPELVGFSVTDRVVSD
RDPEPLAPASRLLEASCKQPLVHFSGKGRDISDLHSFLERMEEHKLENMLCLTGDRLREE
KKGERARYLESVCAIQIAKQARPELQIAAALNPFKYREEDAMAQYLKLGKKVGAGADFII
TQIGFDMHKYEEALFWVGTRNYRVPLVANLLPMAAARARYLRAHQLAGVTITDSFLALLE
AEERLMPDKGASRVLRRLALQILG
>A0A6N1X505|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax antarcticus|TrEMBL
MIHGNALPISYEFFPPKTPEGAEKLRAVRRQLAVRRAEFCSVTYGAGGSTQSGTFSLVQE
IQQEGMSAASHFSCVGATRESVRAELRQLQAMGISRLVALRGDLPSGYGLGGEFQYASDL
VAFIRAEFGDAFHIEVAAYPEMHPQARSPQADLQAFAAKVQAGADSAITQYFYNADAYFR
FVDSVRAMGLDVPVVPGIMPITSSTQLLRFSDACGAEIPRWIRLQLQGYGDDTASIKAFG
LDVVTELCERLRRQGAPSLHFYTMNQSAAVLAISERLGL
>A0A7C6PVI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MNNQNRLRDKLAKKEFTVTVELDPPKGVSVKQTLQAADLLAGSVDAVNIADSPMANMKMS
PIALCHLIQENINLETIFHLTCRDRNIIGLQSELLGAAALGVQNLLILTGDDPKNGDHHN
VKGVFELDSVGLVKIAATLNRGYDYMNNPLNEAANFFIGVAVNPAAKDLDKEIEKFEKKI
KAGACFAQTQPVYDLDKISKFLERTRQFNIPILIGLLPIKSSKMARYLDEKVPGISISKE
IQDRIKLKGREAGIEIAREMLIELKKIADGVHIMPIGDSNLVLEVVDGII
>A0A665UIW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Echeneis naucrates|TrEMBL
MVNPGSCRSDSSGASNSSGDSSKDSSRCSTPVLDADRSDRLRDKMRRRMESGDRWFSLEF
FPPRTESAAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLES
ILHLTCCNQTKEKITSHLAKAKRLGLKNIMALRGDPIGETWEEEEEGFNFAVDLVKHIRS
EFDDYFDICVAGYPTGHPEAESYEKDLRHLKEKVDAGAGFVVTQLFFQAESFLKFLEDCR
AIGITCPILPGIFPIQGYQSLRHLVKLSKLEVPQEITQVIEPIKDNDAAIRNYGIQQTVK
MCRELLDSGKVPGLHFYTLNREVATIEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRP
IFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEDLLQMWGEE
LMNEESVFDVFTCYITAQPNRNGHKIMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINS
QPNINGKPSTDPIVGWGPPGGYVFQKAYMEFFTSSENVTALLKVLKKYEPRVNYHIVNVH
GRNLTNAPHLQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFGLWIEQWGKLYEDESP
SRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFKLLDAPPEECALYF
>A0A6H1JMV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. RPA4-5|TrEMBL
MALGTASTRTDRAHTVRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVRHPDGVDYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVA
KCRAGADFAITQMFFYPEDYFRLRDRVTAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A099LRT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio navarrensis|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSTPQMEETLWSSVQRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLVAAPHLTCIDASRDELINIANDYWANGIKNIVALRGD
IPPGGGAPEMYASDLVTLLKSLHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDDDPVTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKQA
>A0A1Y4TFQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmiger sp. An120|TrEMBL
MYIRQLFAQKPCVFSLEVFPPKQQASYESLQNALRQMAELKPDFISVTYGAGGTAPGGVS
TCQIASFLKNELNIEPLAHLTCVGASEEVLRARLDELFAAGIRNVLTLRGDKNPERPLQP
PFLHASDLAAFVQGQYGSFGLSGACYPEGHPESATLAQDVTNLLKKQQAGVTHLVTQLFF
DELHFYRFLNMARKAGVDLPVSAGVMPIVNQRQIQRTVALSAASLPPKFTKMIARWQDDP
ASLYDAGIDYAIEQLRGLIQGGADGVHLYAMNNPEVARRVWQGIADLL
>A0A547NL67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM4303|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLRPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVVREFAEMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKGAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDSQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A1K1NN80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. NFACC04-2|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGEHFHVEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A533SZL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MNDKTFSIEFFPPQTAEGVEKLRLVRDKLAALKPAFFSVTYGAGGSTRERTFSTVREIVA
AGLDAAPHLSCIGSSRESIRGILAEFQAEGIRRVVALRGDLPSGMADPGEFRYANELVEF
IRAETGDHFHIEVAAYPEWHPQARSADDDLQAFVRKVNAGANSAITQYFYNADAYFHFVD
AVRTAGVTIPIVPGIMPIASFSKLARFSDACGAEIPRWMRKKFEGFGDDADSIKAFGLDV
VTELCQKLLAGGAPGLHFYSMNQSGLTTEIWQRLGLGNR
>A0A4P7VGF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculum gordoncarteri|TrEMBL
MKVTELIASHGKTGFSFEVLPPLKGKGIAQLFRNIDILKEFNPLFINITTHRSEMVYKNT
PDGLYQKVSERSRPGTVAVAAAIQQKYNIPAVPHIICSGFSKIETEYALIDLNFLGITNI
LILRGDKAKHESRFIPNENGYSHASELQLQINEFNRGYFIDGTKMDIITGETFSYGVAGY
PEKHDESPNLDMDIAYLKQKIDNGAEYVVTQMFFDNSKYYDFVDRCRKAGINVPIIPGLR
PITTIGQLNILPKVFHVDMPMQLVSELMKCKDDNDAKEVGVEWCKAQCLDLMAHGVPSIH
FYSLNSTRSVERVAASIY
>A0A1A8XWJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter aalborgensis|TrEMBL
MTKNLRHFSLELFPPQTPEGAARLRVARDQMALLKPRFFSVTFGAGGSTRDRTLATVLEI
QREGHQAAPHLSCIGSTRESIRGIVQEYRAQGIRHLVALRGDLPSGMAQPGAFRYANELV
EFIRAETGDWFHIEVAAYPEYHPQARSPMSDLEAFKRKLEAGANSAITQYFYNFDAYAHF
IDACQGVGIDVPIVPGVMPISSYSSLARFSDNCGAEIPRWIRKTLESYGDDSASIRAFGL
DVVSQLCEKLLASGAPGLHFYTLNQASLTTTLWQRLGLSPAAEA
>A0A353CPY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MKISKMLASGGRTFSFEFYPPKKEEDIPSLKAAISDLKSLGPDFVSITLSQKYMPSWNFA
SISNTLALSGVLKHEFSLEVMAHLTTAIIRDRQTLEETLKLVKILGLENVLALRGDLEPG
REGERAFSYASDLVPAVKSGGDFCVGVAAYPEKHPEASSLGEDVRRLKQKLDAGGEFAIT
QVFFDNAAFFRFRDAAAAAGVTAPIVPGLMPLTSLKQRDNFVAGQGISVPAELSAGLEKH
GGDKDALFAFGLDYASAQAEELLAAGVPGLHFYTFNRSRATREVFRRLNPSRLV
>A0A351UMW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MRVTERLKSGKKLFSFEFFPPKTEEDAKRLFDSARVLKALEPDFVSITNSSSGSAPYRTV
AMAGVLKAELGLETVAHLTCVAHTRAEISEICRRLKEMNVKNILALRGDIHNIDGLSPRR
DYSYATQLVADLKATG
>A0A0C9YE24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pisolithus microcarpus 441|TrEMBL
MKISKKIEQSQKEGKIWWSFEYFPPRTAQGLQNLLDRIERMRNLGPEFIDITWNAGGRTS
ELTSEMVRLCQGVIGIETCMHLTCTNMPKEKVDIALREAKKHGCRNILALRGDPPQGKEE
WEAVEGGFVHGIDLVRHIHKEYDDYFDIAVAGFPQNLLLPAEERDLEIKYLKEKIDAGVN
FIFTQMFYDVDIFIDWVKAVRAAGITIPIVPGIAPIQTWNGFLKATSLAKTKIPQSFMDA
LEPHKNDDEKVRAIGTKLVADMCRKILDADLGIQGLHFYTMNLEKGTKMLLQELNLVPRV
ETLKPLPWRQSLTPNRRQENIRPIFWANRAQSYLSRTENWDEFPNGRFGDSRSPAYGELD
GYGVSLKQREEEALKLWGEPKTFDDIAQLFSKFCLKKLSALPWSDQPVSGETSAIATELS
QINRLGFLTINSQPAVNGAPSDDPKFGWGPSDGYVYQKAYLEFFVNPELLEILISELEMD
TKMTYYVINKQGDLRTNSHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGVK
WANIYETTSPSRKLIMDLMDNSYLVNVVHNDFKDTKAIFEPFFKAGEKYASSRAKANGSA
QTNGNLN
>A0A3N5WUZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MESQKKFARTFSFEFFPPNTPEGAEKLAQTAKQLAQLHPKFFSVTYGAGGSTRERTLRAV
LDLQAAGHAAAPHISCVGSSRNDIREILREYRSHGIRHLVALRGDLPSGTAFAGEFQYAN
ELVAFIRSEFDDQFFIEVAAYPEYHPQARSAQDDLLNFKRKVEAGADSAITQYFYNADCY
FHFVEECEAMGLHLPIVPGIMPIGRFSQLARFSDACGAEIPRWIRRKLEGYGDDAASIRA
FGLDVVTRLCDDLLSAGAPGLHFYTMNQAGLTTTIWQRLGL
>A0A7W6KQT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Martelella radicis|TrEMBL
MIGFLGRRGKQAAADNAAIEPLIEGFSIEVMPRTAAKVDDFKALLPAGTRVYIAHIEGTP
IEEMVGTARRLSDDGFPVMPHFPARIIKDRATLEDWIARYQGEAGVDQALLLAGGVAAPV
GEFHSSMQLMETGLFDKAGFRRLHVAGHPEGNKDIDSDGSTGNVDAALRWKQDFAERTDA
EMAIVTQFAFEAAPVLAWIERLRGFGVDLPVHVGIAGPAKLQTLIKFAIACGVGSSLKVL
QRRAMDVSKLVLPYEPTDVLADFADAAKRDGGSAVAQIHFFPLGGIGACANWAARRSAAA
PASAAV
>A0A1B9YLW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. LMTR 3|TrEMBL
MTEVTPPAFDGHRALHSPKISFEFFPPKTEEMERSLWEAINRLAPLAPNFVSVTYGAGGS
TRERTHSTIARILKETRLTPAAHLTCVGAPKGEIDDVVARYHEIGVRHIVALRGDPTTGI
GTAYRAHPDGYQSSPDLIAGIKKRFPDIEISVSAYPEKHPESPTIDADIDTLKAKVDAGA
ARAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARSFVTRAGTTVPDWLAD
KFEGLDDDAETRKLVAATVAAGQVQKLAKHGVETFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A0J6FEE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccidioides posadasii RMSCC 3488|TrEMBL
MEKISNKIAALPEDADYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT
ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPPRSDE
YNLDGEDDSNKEFTYAVDLVRYIRKKHSDYFCIGVAAYPEGHSDESHPGVQDPVRDLPYL
VEKTKAGADFIMTQLTYDLEAYKRFESMLRNHESGVFKTIPIIPGLMPIQSYPRLTRITK
LSHVRVPPEMLSRIEACKKDDEAVKKVGVDILSELVEGIKTIPGTGPRGLHFYTLNLEKS
VSFILERCNLIPPSSEASSDTDSDSVFASGNLQNGLGTAADKPPLISRRRASSLNSQPHN
RVIVDRADISSQSSITHEASAQGAGMPALNPPHRNTALQISEGMGALGREATWDDFPNGR
WGDARSPAFGEIDGYGPSLHVTANVARRLWGYPTTREDINNIFRQHVSGGLHAVPWSEGG
AAEETGGLSPETITIRPYLLSLIEKRGWWTLASQPAVSGVRSDHPIFGWGPPGEGFVFQK
AFVEFFCSKDDYRSHLKPLLQRYGHDEFAWFATNAAGDFESSTSSSIPVPTGPVDAVFDD
MDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWDEWRRIFPRGSPT
EKLLNRVKEDTWLVCVIGQRFGAGGDPGKDVMEEGKLLWKVLAGENVSLQS
>A0A380DJN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKR
>A0A674NCH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Takifugu rubripes|TrEMBL
ILRVFFILKSVAHLAPSNVLGLFAFEMFPHRVKISWQSSKADSSGASNSSGESSKESSRC
STPVLDADRSDRLRDKMRRRIESGDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFID
ITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQTKDKITGYLGKAKHLGLKN
IMALRGDPVGADWEEEEGGFNYAVDLVKHIRSEFDDYFDICVAGYPTGHPEAESYQQDLR
HLKEKVDAGADFVITQLFFRAETFLKFLDDCRTIGITCPILPGIFPIQGYQSLRQLVKLS
KLEVPEEITSILEPIKDNDAAIRNYGIQLAVEMCRVLLDSGKVPGLHFYTLNREVATMEV
LRQLGLWTEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNS
SSPAFGELNDYYLFYLKSKSSKEALLQMWGEELLSEESVFEVFTFYITAQSNRCGQKVLC
LPWNDEPLAQETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQKAY
LEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQP
TVVDPVSFMSWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDNCL
WQVIDDMFELLDSPAAPPCEDATP
>A0A6I6HMS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax paradoxus|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPEFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFLYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADMQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
ARKLGLDTPIVPGVMPIISSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
ADLCARLRDGGAPALHFYTMNQSAPTLAVLERLD
>A0A3A0VIS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus gallinarum|TrEMBL
MSQLLDKLKHNILVADGAIGTILYSEGLDTCPEAYNITHPDKVARIHRSYIDAGADIIQT
NTYGANFEKLKPFGLEHKVKDIHYAAVEIAKQAANDDTFILGTVGGFRGIKQEDLELSSI
QYHTEIQIETLIDAGVDGILFETYYDLEELTTIIKATKRKYDIPIIAQLTALNTNYLRNG
TEINTALQQVVKSGADIVGLNCHHGPHHMQQSFSHIELPDGAYLSCYPNASLLDIENSQF
KYSDNAAYFGKVAEQLINEGVRLIGGCCGTTPEHIQYIKSSVSDLKPVNQKNVIPIAKYT
GHSEKPTQKQNLTSKVKHRPTIIVELDTPKHLDTDLFFRNIKKLDDAKIDAVTLADNSLA
TVRISNVAAASIIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKTQTNFN
>A0A7Y9JDW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura luteofluorescens|TrEMBL
MRRVRPDRPPTVRELLASGERSFSFEFFPPKTDKGARNLWRTIRELESLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPDGVEYAAELVRMIRSYGDFCVGVAAFPYKHPRSRDIESDTRHFVDKCRA
GADYAITQMFFRAEDYFRLRDRVEAAGCDVPILPGIMPVTRLSTIERSEQLSGAPFPPEV
RARFEAVADDPEAVRRLGIEHAAELCGELLEQDAPGIHFITFNQSTATREVYALLDGAGY
GARGSRPPITA
>A0A845WVW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirulina sp. SIO3F2|TrEMBL
MTSSLSRFRRAVCDREFLVTAEVMPPKGGDPSHMLEMAHKLKGRVHAVNITDGSRAVLRM
SSLAAAVLLHQQGIEPIYQLACRDRNVIALQADLMGAQALGVQNVLALTGDPVQAGDHPQ
AKRVFNLESVRLLRLIGGLNQGLDFNEKKLPDGALNLFAGGAVDPQCPSWSGLERRFERK
LAAGAQFFQSQLISDFARLDKFMTQIASKGDKPVLAGIFLLKSAKNAKFINRRVPGVNIP
QSTIDRLAAAENPLQEGVKIAAEQVQQARNLCQGVHLMAVKREDLIPDILDLAGVGAIG
>A0A674NP51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Takifugu rubripes|TrEMBL
MTNADSSGASNSSGESSKESSRCSTPVLDADRSDRLRDKMRRRIESGDHWFSLEFFPPRT
ASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLT
CCNQTKDKITGYLGKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAVDLVKHIRSEFDDY
FDICVAGYPTGHPEAESYQQDLRHLKEKVDAGADFVITQLFFRAETFLKFLDDCRTIGIT
CPILPGIFPIQGYQSLRQLVKLSKLEVPEEITSILEPIKDNDAAIRNYGIQLAVEMCRVL
LDSGKVPGLHFYTLNREVATMEVLRQLGLWTEDPRRPLPWAVSAHPKRKVEDVRPIFWAS
RPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEELLSEE
SVFEVFTFYITAQSNRCGQKVLCLPWNDEPLAQETNLLKDELEKVNRRGVLTINSQPNIN
GKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLT
NAPDMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLYEDESPSRMII
QYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDSPAAPPCEDATP
>A0A3M7M0U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenophora seminiperda CCB06|TrEMBL
MNRQLIDEALEQAKVLGIRNILALRGDAPRSEEYRDEDTPPEQDSNKDFVWAIDLVRYIR
KEYGDYFCIGVAAYPEGHSDQSHPEHQDPLFNLPFLVEKTKAGADFIMTQLFYDVEAYDK
FEKMLREHESGVFKTIPIIPGLMPIQSYKILLRTTKLSHARLPAEMLARLDAVKSDDELV
KQVGVQIMDEMVEHIKARPDTCRRGFHFYTLNLEKAVSHVVEDTKLIPTTMIDDDEVIVE
TTPAINLEPPPNGIALHRRRSSAVNSGPFNRVIISHGSGAKSSNHSYEATEEEAGVPRGP
INTRANTLAISEGEGSLGREATWDDFPNGRWGDARSPAFGEIDGYGPTLHVSTPQALKLW
GYPVEKNDISTLFRRHIEGDLEAIPWSEQGLSPETSTISKQLLALNAKGWWTVASQPAVN
GVKSTDPIFGWGPKNGYVFQKPFVEFFIPSSQFALLKPKLEAHDQVTWFAGNAAGEFEAS
QDDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWLDEAFSIWKEWQRIYPPRSASSVLLGEL
RQDHWLVNVIWGDFVNGEGLWEFLSQ
>A0A0S8L2J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillales bacterium SM1_46|TrEMBL
MDSQAKFSRTFSCEYFPPKDEDARAKLDETTRELATLSPAYFSVTYGAGGSTRQGTYETV
RALHEKGLTAAPHISCVGASRESIRDQLLGYKALGIKRLVALGGDLPSGMASPGEFRYAY
QLVELIRAETGDWFHIEVAAYPEVHPRATNAEDDLAHFRHKIDSGANGALTQYFYNADAY
FCFVDECERIGVDTPIVPGIMPITNYKQLARFSDGCGAEIPRWIRKRLEGFGDDLEALRA
FGLDVTTELCRRLLDGGAPGLHFYTMNRAGPTRAIWQRLGL
>A0A4S4M072|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bondarzewia mesenterica|TrEMBL
MGFVDILQASDRPFYTFEFFPPRTDQGFNNLLARISRLAELKPLAINITWGSGGSTRDRT
LELSSLTQREYGIDTVMHLTCTNMEKGMVDDALKAAKXLGIRNIMALRGGRXSALYIPKI
HMIKVLXRSSARRGILDGHRFPIQPXSXPGVVRYPDGHTDKNGSEDDEIEHLKAKVDAGA
DYIVTQLFYDVDNFIRWIRKVRGKGIKVPIIPGIMPLQTYSSFVRLTKLTGTHVPSSIQA
ELDPIKHDDQKIKDYGIALAVKTIRQIYGESGIRGFHFCTLNLEKSIQKILETLGWAPGS
SKFQNRLIAEDPTRPSTPTKDFIVTPASATDLAATGLASHHTAGEGDIGKGEVNNAATWD
EFPNGRFGDVNSPAFGNQDLWGNFCRLPKQWPRPKSPAEITLICTHFLSSETSSWPFSPT
PLSLESQLILPHLKRLAQLGWWPVGSQPAVDGEDSGDPVLGWGPANGYVYQKPFVEFFVG
EGEVDKLEKRIKQEGKGIVDFFAANNMGDVRTNVAEGDRNAVTWGVFPGQEIVQSTIIER
ESFFTWKEEAFSIWKDWASLSPPGSEERKLLEEIQKTRWLVNVTHHDFKDPDGLWKFLFE
GLSETAPTMSVATPTVIPRSPLFPTLLPRPPQPHPLPQPRPGRYEARINSRRDLVQEMDD
LSDEEAEVDDISAEVKKRGFAFLVPIGKTLTQHEEKNDADEGSEEGGSAASSHDESVGSP
TTSDAEEDGEDDEDDEDEDGQDLDAEMEDLDEVGDNTAETEDLDEMDGTEEFDDD
>A0A412QZ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides distasonis|TrEMBL
MKVIDLIRDSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIHYLKEKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A4D6YLM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MKKFYNSCATMHQNIFDIRSKLNISFEFFPPKVFHQQENNFFTAIKKLSVFCPNFISVTC
SPQVEHTIDYTYQAIRHIPKELNLNIAPHITYINNIDTIKEIAQKYWNHGIRRIVALRGD
IISKEYHSEVYASELVTLLKEIADFDISVAAYPEMHPEAKDMTSDLIYLKKKIDCGANRA
ITQFFFDADTYLRFRDRCVDIGISVDIVPGILPIINFSQLKRFLRLTNVSIPSWMCDVLN
NVDNNDIYVNKMIGLMIAMNIIQKLCSAGVRNFHFYTLNNFDITYALCSILTAK
>A0A252C2U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter sp. DsW_063|TrEMBL
MPRDEASLRNDAGEALAFAPQADTINIPDLMRFDLRSWKAVSLVRDRVNAAIPHIRAIDV
DPNEPLPGTDDPAIREVLVIRGDPPADLNRRTFPNSSESIIRRYQREAPGVAVYAAFDPY
RQAPYQELDAVQRKRDAGARGFFTQPIFDMRMLDLCREWLSGENVFWGLSPVIGPRSRSY
WETTNRVIFPRNFEPTLDANIAFADAAIRSIRSDSGSVYIMPLRVKLANYLTPLAAALSS
>A0A3M7MFU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenophora seminiperda CCB06|TrEMBL
MHISQKLAQAREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQTVYGLETCMHLTCTDMEKSKLDDALREAYQSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIREKYGNHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGGTF
IVTQMFYDVGIFLDWVSKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTKCNIPQHWTDAL
EPVKNDDVEVREVGKILVADMCRKLIAAGITHLHFYTMNLAQATRMVLDELHLLPDGEAP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNVKLWGTPMCIRDLSNLFVSYMEGKLGSLPWSEQAITTEAGPIQNDLID
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDIVDTWYLLNIVHNDFHETRGIFPIFNGLEVQDMDKPLYNPSSDI
PGANGDVLTNGTNGTNGSSESHKKEAPGLIETAKAAAVEITNGMRSLAVSN
>A0A4R1S6H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK251|TrEMBL
MALKGVNGRGDIRVSFEFFPPKSEEMEAQLWSTVADLQAWDPDFVSVTYGAGGSTKAPTL
TTVGRLIAETPLATASHLTCVGATREDTHRVVEELCATGVRHFVALRGDPAGGVGTAYQP
HPGGYANAAELVAGLRDLGDFEISVSAYPEKHPESRDTAADIDMLKAKADSGATRALTQF
FFDNDTFERYHDRVRASGISIPVVPGIMPIQNLTQLKRFAGACGASIPGWLDERFAGLDD
MPEERAKVAADVAAEQIEDLARRGVHEFHLYTMNRAPLVSAVLERLGLERKAGRRAGAAA
>A0A374TXK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. TF08-11AT|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFNTPSVAHLTCVGRSHADIAAKIDEYRSAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A7K6IDJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dasyornis broadbenti|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A1Q6WH05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium 13_2_20CM_69_10|TrEMBL
MPHAFDRRLAAGPLLCDGAMGTLLYARGVSIDACFDVLNVSQAKVVQSVHSEYIAAGADC
IETNTFGANRFKLAVHGLASDVHQINLRGVKLARDVRESMGRDVLVLGSVGPLGKYLAPL
GTVTADEARAAFREQAEALLEGGIDAFVVETFSDLTEIALAIETIRTLTDLPIVAQMAFT
DEGVTFAGRSPAEVARTLRELGVRALGANCSVGSSTLYEVLEAMGPEARDVPLAIQPNAG
LPHRIGERLMYLSSPGYMADYAGRMIDAGARIVGGCCGTTPQHIAAMRRVLDARAPASKA
EPRPTSAARVIEALETPGLRTTLAPTLLGRKLEQRSFVVSVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLPTAILVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALGIRNILAMTGDPPRTGDYVNATAVFDVDGIGLLEVLRRMNEGMDATGNGIGEPTSFCV
GAALDPGAPDPGREVERFHRKLEAGARWFQTQPVYDLEVLDRFLARVVGSPVPVLVGVLP
LHSFRHAEFLHNEVPGITIPDGVRARLRAAGDGALRAGIDMAQQLVGEIRSRYAGAYLMP
SFGRFEVVAEVLDVLR
>A0A6I6LDX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingorhabdus lacus|TrEMBL
MQEASRALADPLFAGLPGDCEISFEFFPPKTEKMEEQLWDSVVTLAPLAPRFVSVTYGAG
GSTRERTHSTVARIARETSIPAAAHLTCVEATKSEIAEVAHAYWEAGVRHIVALRGDSPT
ADGRFTPYPDGYASAAELVEGLQKIHPFEISVSAYPETHPEAASAATDIDFLKRKLDAGA
SRAITQFFFEPETFFRFRDAVAAAGITAEIVPGIMPVSNFAAITRMSNMTGTAIPAWMAH
LFEGLDDHPPARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLGKRPVSA
AQEKAA
>A0A7Y0VHR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. WS 5406|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFSPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2H1SRQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. fuscans|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A7X5YFE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricimonas paravirosa|TrEMBL
MKVIDILNNTDKAVFSFELVPPLKGGDINKIYEAIEPLIALAPPFINITFHRDEVVYREY
PDGTIKKVTVTKRPGSVALAAAIMRRYNVDMVPHIVCGGATRHKIENELIDLNFLDIENV
MALRGDPIPGERFFTPEEGGHQYSCELVEQITRMNHGQYLDDTLTDAVPTNFCIGVAGYP
EKHYEAPNQACDIENLKKKVDAGVNYIVTQMFFDNSKFFQFVDKCRAQGINVPIVPGLKP
ISTFKHLEMLPRTFSIDIPHELVKEIRSCKNNKEINQVGIEWCVAQSKELIAHGVPAVHY
YTMGKSENIQEIVKQVF
>D5E8B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP)|TrEMBL
MSLKTNVTYYPAMPSAFKDKLLSDDFVITSEISPPKGVDVSSAFEEAGLVGNYVDAFNVT
DNQRAVMRMSSLAMGRLLKEQGLDVILQLTCRDRNRLALQSDLLGAYALGMENICIMSGD
YPTKGDNPGTKPVYDLDSVQLLGATSRLEGGYDIAGNPLESVPSFTKGAVCNTEPDQPLQ
LMKLEKKARMGIDFFQTQAVYDIGHFETFMDSISHMEVPVLAGLIPLKSAHMARFMNDKI
PGIRVGDELIERMEASTDPAEEGLLICAEQIRELRKVCRGIHLMPIGHYRHITALFEIAG
LHEKN
>A0A1Q6S3Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:108-related_41_35|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A2V5ZG48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRGDSPTFSFEFFPPKTPAAVEVLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEDEIEAILLRYARSAIGNVLALGGDRPRDIPYDKSR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALVDIHIPIIAGIMPVT
>C1H0K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01)|TrEMBL
MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKTRLERMSQALRPLFVTVTWGAGGST
VSKSLELAEMCQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTHAVDLVRYIRRMYGDYFCIGVAAYPEGHSDESHPEVQDPARDLPYL
VEKRQAGADFIMTQLIYDLEAYKRFEEMLRNHESGVFKTIPIIPGLMPIQSYHILTRTTK
LSHAKVPPDIMARVEEVKADDEAVKQIGIDILCEIVNGIKKLPCPGPRGLHFYTLNLEKA
VAFIVERCSLIPASSEPSSDSDTELDSAVFITPGMKNGVPLISKRRASSLNSQPHNRLIV
DHPASLSIGAASSQTSTTHETQALGAGMLALNPPHQSTALQISEGMGALGREATWDDFPN
GRWGDARSPAFGEIDGYGPSLHVNANVARQLWGYPTSKEDINKLFHCHVSGELHIVPWSE
GGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSDHPIFGWGPRGEGFVF
QKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGITGLDDAVPDY
NGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGDEAFRIWDEWRRIFRRGSPTEQL
LDQLKKDAWLICVVGQKFGAGCGSKEASEAEEKFLWRVLAGEEDTEANPTRLY
>A0A1E3WKE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio scophthalmi|TrEMBL
MGYTHASHIDALNQNVAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKNLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLIAAPHLTCIDASRQELVQIADDYWANGIESIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFNQASRFAAQNHVKVPGWMAKQFE
GLDDDPTTRQLVGASQALDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQASLA
>A0A2H1SVF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. fuscans|TrEMBL
MSPNHHDKTARPVIPTDTPSGASTITDAYSLEVSVKDIGALTNAAPGILPGCAMFIPYLP
GQTEAARLAAAQMVRRLGFEPVPHLSARRIGSLEELQAFIARLVGEADVTGCLVIAGDPS
TPKGPFADSVSLIETGVFERSGIRTIGVAGHPEGHPIMRTTEQWDVLQRKCRSIQERGMA
PLIVTQFGFDADIVMTWLEALRARGMTHPVRVGVPGPASVGVLARYAASCGVGACASVLS
NYGVSIGKLFGNAGPDRFVDHLVGRLTEAHGDVRLHLYPFGGIAQSVEWVAHYRSCKASQ
DRVSSVAAD
>A0A2V6L8U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRRDSPTFSFEFFPPKTPEAAEILYQTIRDLESYMPHFISVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCICHSEEEIEAILLRYARSAIGNILALGGDRPRDIPYDKSR
DSFQHAVDLVKFIRRFNESGAHPDDRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYMVTQLFFDNRDFLDFRERCALAGIHIPIIAGIMPITSISGFKRIAELAGGARFPAKLV
RALQRCENDPEGVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRVIFDSLGIPRRR
SARAPTA
>A0A2V6CW36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
RTQFVIGCTFNPNAKNLDSQVNRLERKVAAGAQFAMTQPVFDVRLVKETKRRTAHLDIPI
FIGIWPLMSARQAEFLHHEVPGIIVPDEVRKRMADVPPENGSGVGMEIAREVVAAVGAEF
PGVYLITPFLHFDCTCELARFARKM
>A0A522DS48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylovulum sp|TrEMBL
MQSQKTHPQLFSFEFYPPKTEEGAVSLQAVQNQLAELKPDFFSVTFGAGGSTRDKTFDTV
VDIQSKGIAAAPHLSCVASTRANIRAILNDYWANGISKIVALRGDLPSGMMSAGEFRYAN
ELVEFIRQETGDHFQIHVAAYPEVHPQAANGNDDFKNFKRKVEAGADAAITQYFYNAEAY
FYFVDSCEKNGIDIPIVPGIMPITQYAQLFRFSEMCGADIPRWLRKRLEAYGDDRASIQA
FGLELVSDLCRRLLDNGAPGLHFYTMNQAGPTLGILANLSLA
>A0A1Q6S338|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:108-related_41_35|TrEMBL
MKISELFKKKIVLSYEVFPPKPTAPVKTIYDTLNELKKLSPDFISVTYGAGGGKNNNETF
KIASAVKSLGIESVAHLPCIGLTKEDVSDKLQELKERGIENILALRGDIPNEGYVQGDFE
YASDLIAYIKSQGDFNIIAACYPEGHIEAKDIIEDIQNLKIKVESGADHLISQLFFNNDY
FYSFRERCQLAGINVPIEAGIMPVVNKRQIERMTSLCGASVPKKFAAMMERYENNPIAMR
DAGIAYAIDQIVDLITQGVDGIHLYTMNNPYIARKIYEAIHSLRIKTISEN
>A0A1X1HW57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A8H4HMN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neosartorya fumigata|TrEMBL
MHVKDMLTDNESAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEA
WEATEGGLRYAKDLVKYIREKFGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
VITQMFYDVDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEAL
EPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQATQAVLEELKLIPSEETP
LQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSIRDITQIFVRYLEGKLDRLPWSDSPISGEANAIKDNLVQ
LNSRGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNP
DLTYHAVAKNRELRTNTRDSPNALTWGIFAGREIVQPTIVDTISFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQDIMDNWYLVNIVNNDFHNTYDLFDLFNGLEVKDLDLEVGPDTAETK
SQPNGAAPEEVAIKN
>A0A845YAK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symploca sp. SIO2G7|TrEMBL
MTQPTHNSFRAAAQSGEFLITAEVAPPKGGNPNHMVKMAQALKGRVHAVNITDGSRAVMR
MSPLAASVILLQYGIEPICQVACRDRNRIGLQADLLGAQALGIHNILALTGDPVKAGDHP
EAKTVYDLDSVRLLKIIAGLNQGLAANDKTLTDGTTDLFAGAAVDPQLKSLSALQRRFER
KIEAGAQFFQSQLITDFERLDKFMDKVAAGTDKPILAGIFLLKSAKNAQFINKYVPGVNI
PEAIIEQLAAAANPLQEGIKIAAEQVKIAGQICHGVHLMAVKREDLIPQILDLAGILPLN
KAS
>A0A0E0T9G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. (strain Y412MC52)|TrEMBL
MGLLDELKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPNRAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIEAMAKALSDRTPVTEKTVKRRAVSVS
VQAERPAPSPLPELARTHRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKEQLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKANFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACSGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A0D0QF71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. L_1B0_5|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAVIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8B0SP26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiothrix fructosivorans|TrEMBL
MTDDHQHDHHHDDLIFSFEFFPPKTDKGAENLRAVRNELAALNPRFFSVTYGAGGSTQAN
TLNTVLEIQRDSGIEAAPHLSCVGSSAEQIREILDTYRNNGIKHIVALRGDLPSGSRDLG
QFRYANELVEFIRKETGDHFNIEVAAYPEMHPQAPNLKVDIDNFVRKVNAGANSAITQYF
FNADAYWHFVDECVKKGVEIPIVPGIMPITNYSQLARFSDMCGAEIPRWLRKQLETYADD
VESIAKFGEEFISLLCENLLETGAPGLHFYTMNRVEPTMSIWKNIGLAD
>A0A7D5YBP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora carbonacea|TrEMBL
MALGLPSVLPNPQPSIGELIRDRQPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVR
GDPPGDPGGEWVRHPEGVLYAEDLVRLVRDCGDFSIGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAEGCDTPILAGVMPVTQLTTIERSVQLSGAPF
PPALAARFAEVADDPEAVRRLGIEQAAEMCRRLLDEGVPGIHFITLNRSTATREVWQQLE
VSARV
>A0A0B7MQ55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceticus schinkii|TrEMBL
MKEIKPENLKSGSNLEKVLASGQFACTGEIGPLTYATFDNIDKHAEEMRGLVDSVNFTDN
QTAVVRLSSWAASLRLLQLGMEPNLQMVCRDRNRLAMQSDFLGAYAHGIRNVLCLTGDHQ
AFGNHPGCKGVFDVDSVQLIHMLKTLRDDGCFECGAECKIAPKFFIGCAANPFADPFEFR
VTRLEKKIAAGADFVQTQCILDMERFEKFMELARERGLHERAHICAGIMPVKSPRMARYM
QTGVPGMIVSEEFCQRLEKAEDGKAEAVEISVEYINRCREMEGVDGVHVMAVAWESIVPT
VVEKAGLLPRPTF
>A0A1A9IVJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SAT1|TrEMBL
MALGTASTRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPRGLRYAAELVELIKTSGDFCVGVAAFPAMHPRSVDRDTDVRHFVD
KCRAGADYAVTQMFFDPEDYLRLRDRVAAAGCETPIIPEIMPIASVKTLARIPSLTNAVF
PGALKERILAAQDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
PHRSPRA
>A0A5P1YNR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces tendae|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADTTLTPVAHLTAVDHSVAQLRNIIGQYADAGIRNMLAVR
GDPPGDPMADWVPHPEGLTYAAELVELIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPQLSNAAF
PDALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A381I6T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridioides difficile|TrEMBL
MAGTDMAGNKLKGSPDFYLGASVTPEYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMR
KFRELTRDMDCKVLAGIVPLKSPGMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIK
MAGELIKQLKEEDLCDGVHIMAIGAEENIPAILDAAGL
>A0A2S8EYE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium WD3A24|TrEMBL
MQDQDMQVSFELFPPKTEAGIARLEGTVDDLARAAPDYFSVTYGAGGTTRQTTHRVVDMV
RARGGRPVAQHLTCVGANRAEIEAQAKALWDDGIRKIVALRGDLPEGQSLPADGFKNAAE
LVEALRRVADFDIAVAAYPEPHPDSRGEEADLDYLKRKIDAGASCAITQFVFDTDTVLRF
VDRARAAGVEAPIIPGIMPVHNFATLKRFSAGCGASIPGWMEEMFAGLDDNPALRGMVAT
SVAVEQCRRLMDAGLDRFHIYTLNKADVTLAICRALGLPVDLPAQAAA
>A0A452RYD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ursus americanus|TrEMBL
MVNEPRGDGGPPPRSEGSSSGSESSKESSRCSTPGLDPERHDRLREKMRRRMDSGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSREQITGYLQKARRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRH
IRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFQFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQQLLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFAHYLSGEPNQQGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLENCLWQVVEDTFELLNQPAPEGETEAL
>A0A2E7QYB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSSAKRKISSELPFPAGAPRDLKVSFEFFPPKTKEMAESLWAAIKRLELFQPEFVSVTYG
AGGSTRERTHATVVRILEETNLVPAAHLTCVNSTRDEVDTVARTYWEAGVRKIVALRGDP
ADGKSAYKPHPGGYAYAVDLVAGLRRIGDFDISVAAYPEIHPEATSVEADIDNLKRKLDA
GANRAITQYFFGAEPFLRFMDRVRAAGIEVPIIPGILPVQNFSQVIKFSNLSGVSVPSWM
TELFDGL
>A0A7J7N4E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingdonia uniflora|TrEMBL
YEIWLALAVYTIHERFSEGFRKKVARLARIVKDDIALGLAGRYKEIVFFSEVEEGNVLDD
AKWIEWFPILLPSVTSLGDWGIGGYKADLTLDIANNKKMQNMICVEIMRHLTCTNMPAEK
IDHVFDTIKSYGIQNVLALRGDPPHEYDKFVKTEGGFACALDLVKRKREKYTLTAHTMKF
LGFENFGVYYIGGFGSCSIVGYV
>A0A7X4INN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
ALGIPNILCLTGDDPKKGEEPDASPVFDLDSAGLMRLARRMRDDGLLNAGREIKGPPKLF
IGCADAPMAPKPDWEPKSLRAKIDAGADFAQTQYCFDLETAKIYFTRLADFGITEKLAFL
VGIGPLASLRQAKWMDENLFGVSIPDAILKRLEGADDERAEGKKICAELIQQLREVPGVR
GVHLMAPRQESAMAEVIERSGVLEDRPALAG
>A0A7Y5CS98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MQKTLREKLFQTRDFLLGVELLSIRGSMTEKSAVKARDFANDLVACPAVDWISITDNAGG
NPKLAPHALGKPILYAGKEVVIHMTCKDLNRNGLESQAWVLSSEGFHNILAMTGDYPVSG
LGGMAKPVFDLDSIGLISLLSKMNRGFELRKNGVPHAAERLGKTHFLIGAVTSNFKLREG
EVAPQYLKLQKKIECGAQFIINQVGYDSRKMHELRVYMDQHAMQYVPLIGNVYVLNPRVA
QIFHDRKIPGIVLTPPLLEICLEQGKSADHGRAFFYEFAAKQMAIYRGLGYRGAYLGGVF
DFAAVARILEIERAFSPDDWKQFAREIRFSRPGEFFYYAENPATGLADPAARSPVAQPRR
SKRIGPVYRISKAVHGVMFNRDRVLARWGKSVCQNSADSSQGPKLLRAVEWVSKLVLYDC
RDCGDCSLPEIAYLCPESQCAKNQRNGPCGGTKDGLCEVEGFGDCIWLRAYERRKYDGNE
RELLRHVPVLQNQALRGTSSWANHWRGRDHAATASDQAGTAAVKAGNVEARELQLPS
>A0A6B1HLF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MADNRGRRQGRPGRRRRISGMAEKTMNGPVSANGLKSGGNLERVLAAGGFAVTCETSPTA
TTDLAPLLERVAPLKGVADAVNVTDGATAKAHVSSLVLAGAMMRQGIQPVLQFTVRDRNL
IALQGDILGAGALGIPNILCLTGDDPKKGEEPDASPVFDLDSAGLMRLARRMRDDGLLNA
GREIKGPPKLFIGCADAPMAPKPDWEPKSLRAKIDAGADFAQTQYCFDLETAKIYFTRLA
DFGITEKLAFLVGIGPLASLRQAKWMDENLFGVSIPDAILKRLEGADDERAEGKKICAEL
IQQLREVPGVRGVHLMAPRQESAMAEVIERSGVLEDRPALAG
>A0A2D6JTT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTGNAPHLAVAAPLPHDVRVSFEFFPPKTEKANKTLWDSIQRLAPLRPSYVSVTYGAGGS
TRERTHATVYRIRHETALEPAAHLTCVGAATDEIDDIARSYWQAGVRHIVALRGDPPEGD
DRYRPHPGGYAYASDLVAGLKKVADFEISVAAYPETHPEAASAEDDIDNLKRKIDAGASQ
AITQFFFDVEVFLRFRDRAQAAGITVPLIPGILPVTNFARLAEFSIKSGASMPAWMAELF
DGLDGDPETRKLVAASVAAEQCRALHGHGVTEFHFYTMNRADLVYAICHILGVRADDGA
>A0A679G825|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas otitidis|TrEMBL
MSLLREALHTGSFLCIVEFVPKPDTARFAAFAQLMARGHLCGWPLCAAMADRVAGPADVP
PAEAVTRLPGTVPALLHFSGKDRERRDLLAQLETMTAQGLDQLLLLSGDRAARHAPGQRE
VRYLESVPALEIVRQARPDWLLGAALNPFKYREEEGGAQYFKAEKKLAAGADFLTLQLGF
DARKHQEAQQWMQRQAHPVPLLACVMGLTGNRAALLERVPGVVITPSMRAVLAAEAAISP
AYADARSLDRLALQILGLKLMGYAGIHLSGVHTVEQLVALEQAIAARQEQFHDLEQWWNA
WDASWHVEGAPPVVFSPEDADWRLGESRVTASPREQLRYHLLAALHHLLFSRDTLISRAF
GRLLGGRLWRTSWGARWLHRLERSLKRPVVGCDTCGTCRLEATLYICPETCPKGLANGPC
GGTRLNRCEFGDRECIHSIKYRTAKAVGQTRVLSDRLIPCVALETRHQSSWPRWFDARTE
RPAPPAAAPVPREH
>A0A8C5AH58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gadus morhua|TrEMBL
YMLPKPQGLTMVNQVQRVDGSWQTSKSDSSGASNSGESSKESSRCSTPLLDADRSDRLRE
KMRKRMESGDPWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSNKET
SSMMIASTAVNYCGLESVLHLTCSNQSQETITGYLTKAKQLGLKNIMALRGDPLGTDWED
EEEGFNYATDLVKHIRSEFDDYFDICVAGYPTGHPEAQSYAEDLQHLKEKVDAGADFIIT
QLFFRADTFLKFLRDCRAIGITVPILPGVFPIQGYQSLRQLVKLSKLEVPEEIMEVIEPI
KDNDAAIRSYGIHQAVEMCRVLLDSGAVPGLHFYTLNREVATTEVLRQLGLWIEDPRRPL
PWATSANPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFY
LKSKSSKDALLKMWGEELTSETSVFEVFTSYITAQVNRGGHKVMCLPWNDDALATETNLL
KDELEKVNRRGVLTINSQPNINGKPSSDPIAGWGPAGGYVFQKAYLEFFTSSENVTALLK
VLKKYEPRVNYHIVNVQGHNMTNAQDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEA
FALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQVLDDMFELLDAPP
EVVGDGALAPVALGDGALAPVGLGDGALAPVALGDGALAPVGLGDGALEPVVGDGAPQPL
SASQ
>A0A7J7LEP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingdonia uniflora|TrEMBL
MKVIDKIKEASTEDKVVFSFEFIPPKTEEGVDTMFEKMDQTVSHSPSFSNITWGVGGSTV
DLTLDIANNKKMQNMSYGFDKFVKTEGGFACALDLVKHTMEKYVLTTHTMKACLLEFEFG
QMKKKKRLLLCWPMLMISSCICCYRTVLIPGIE
>A0A5E6MCV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylacidimicrobium tartarophylax|TrEMBL
MANLLESLSERLVLGDGALGTYLYSLGLPHRYCLEEANLSRPDLVRRAHADYCQAGAELL
RTNTTGSNRAYLSRFGLEGQVVAINRRGVELAREAAGGRECTVAGSVGPIWLRPWEGSLS
PEERRPLYREQITALLEAGCDLVFLETFTELSEALLALSVAYEAGASRVAVSLAVFEEGR
LGNGDTLASGFASLRGAAARLVGIGGSCGILASLHLLEEIEVRPGDLLCAFPNAGKPEFY
EGRLSYSASPEYFAASVDRFVEEGVHLLGGDYGTNPLHIAAMAPVLARHRPLRVKPRRGR
VPVIEMEREKELPKAEEESLLDRCKRKRIAMVELDSPRTLAMDKFLEGVRALEKAGVDAL
TLADNSLAILRVSNLAAAVAAQRCARLPTILHLACRDRNLLGLQSELMGLSVLGFRHVLA
LTGDPAKAGDHPGATSVYDLNSLGLIKLMAKLNGGVSAAGRDLKAKTNFVIGCAFNPNSV
QFDSQVRKLESKIAAGAQYAMTQPVFDPELIRKSAERLKPLGIPVFVGIMPVLNSRNAEF
LHNEVPGISIPESLRERLRHVDGPKAAELGLEEARSLAETVLEQFGGIYLITPFMRYDLS
VRLVEALF
>A0A0V0RJU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella nelsoni|TrEMBL
MNSSYNLQVKLKSPAYQRAVTVAKVGNPSQQNDFGVYFEEDSFLSLMASLEAVQLKATRH
DLNSAAKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTTEGLINLLKRVDIFANSQP
LFVDVTWVMRSDPASEKVTSSSSLADCILNFCLLDTMLHITSVQYDEKTVLFNLERAKKI
GIRNILALRGDISDDAHVTTTDFQYACQLVRFIRSHYGDYFTICVADAGADFIITQLFFN
EMHYFKFVSDCRKIGIVVPIIPGILPILSYQSIMKIVQLSKIVIPDSVLTTLESIKENAE
AVRNFGISFAVQLCRKSILEQLGFWKKAPVRMFPWKKHTVHSLRCREAVRPIYWTGRPKS
YLCRTRDWKQFPHSRWGDVGNPTFGDLKHYLFSCIDQMDDSCALDMWDKELSTLEHVRDI
FCNFIARTPNRHGHSVRRLPWNENHLDPAADILKNELIYYNSNGILTINCQAAVNGLPSS
DPIFGWGEANGYIYQKVDARCILISLGYLEFFASSTCTTILLNHVQNFPSINYHAINFDG
SFETFNYDEDATVALTWGVFVGQEIVQPTDEAFDLWQRWAGLYESGSIGRKLLQKIHDDY
RLITLIDNDYPQPCIFSLVLPN
>A0A1I1MH88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kushneria avicenniae|TrEMBL
MSDACSPNISFEFFPPRTDAGRDRLPEVYTQLAELDPRFFSVTFGAGGTTRDFTFEAVKN
ISRDTGVCTAPHLSCVASDKADLRRLLLQYREHGIKRIVALRGDMPSGMLGIGEFRYAKH
LVDFIREETGGHFDLTVAAYPECHPQASSFERDIDHFADKVRAGADMAITQYFFNPDAYH
HFVDRVRARGVDIPIIPGIMPITNYSKLARFSEMCGAEIPRWVRRQLEAYGDDSDSIQAF
GHEVVTRLCQQLLDQGAPGLHFYTLNQADTCTRIVRELSL
>A0A2E2CYS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSHAIRIGFEVFPPKSGSSETFENSVATLATIGDYVSVTYGASGSGRERSETAINALVAK
GQANKIAAHLTASSQSRDQIDRLARDWKAKGIHRIVALRGDAPAVTGDEYPCAAALTEGL
SKIGGFDIAVACYPEGHPKSASKAAEMDHLKRKFDAGASEAITQFFFNIEDYLRFRDDCR
AAGIHQPIIPGLLPIASLEGLHRFAAGCGAKVPGWLDARFAGLEDDPETVRTLSVATTVS
LSDRLIAEGVDHIHLYTLNRVRDALTIARALGITGTESAVITQKEEAA
>A0A1J5A2P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium CG2_30_64_16|TrEMBL
MNTDNRGIPSVQDPPNSPGQHVSNLAAILKSGRFAVAAELSPPKGVNLDSIARDAATVRD
YADAVNVTDNQAASVRMASIPVAALLLTHGVEPVMQMTCRDRNRLAMQADLLGASALGIR
NLLCLSGDHGIWGDHPEAKNVYDVDSIHLVRMARNLTEHGVMDNGRPISPAPQLFIGAAA
NPFAPPFDYRPARLGKKVAAGARFVQTQLIYNVERFKTYMARVRDLGLHEVVYILAGVGP
VKSVGAARFMAEKVAGMEVPAEIVDRMAKTPKAAQPEEGIRICVEIIEQVREIPGVAGIH
IMAVHWAEAVPEIVTRARLYPRPPRILTSSPLFEALEEINHPLTP
>A0A3R8NEV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus halitosis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIISDVEPQKDFRYATD
LIEFIKEQAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A415UEN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum hallii|TrEMBL
MNTMQTNPQDILKTLSLSFEVFPPKKWEDFPGLYETLDELKGLHPEFISCTYGAGGSNSK
KAAEIVSHIENELGIRSIAHLTCAALTEDKLLSTIENFKNAGIHSVLALRGDKPFDMSEE
DFANRQYKHPSEIIPILKKAGFRVAAACYPEKHYEAPSMEEDLHWLKHKVEQGADALISQ
LFFDNDAFYRFMDAADQKGITVPVHAGIMPITSAKMINTTINLSGASIPKALSDLIATYG
ENPSDMRKAGIEYAARQINDLAEQGMHYVHIYTMNHSETAKEICGLIK
>A0A3N9N9K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MTVKEILDKTRITFSFEFFPPKTEQGWDNLFHSIADLMPLKPSWVSVTYGAGGSTRDRTH
DLIMRIKKETDLTAVAHLTCVGSSREEIADIVDRYVENNILNILALGGDPPKDATLKPAQ
DGFRYATELVEFIKSRHSQICIGVAGFPEGHPATPNRLLEIEYLKAKVDAGADYIITQLF
FDNRDFYDFCERCRLSGIDSPIIAGIMPVLTKKGMYRMVDLAAGVRLPARLLKLVSRADS
DDYVAKAGVHWASEQVRDLLDNDVRGIHFYTLNKSPATIQIYESLGVRTSEQFLL
>I2QMF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. WSM1253|TrEMBL
MTDATMPAHTDGQDGYLKRPAISFEFFPPKTEDMERNLWDTINRLAPLDPKFVSVTYGAG
GSTRERTHATISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTAYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDDDIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRAGTSVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>F6FQR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Isoptericola variabilis (strain 225)|TrEMBL
MVAEASPQNPAHRHRPTVSFELMPPRRPDAAPKFWETARRLVATHPDFVSVTYGAGGGDR
ATARRVVATLLEGTPVLPIAHLTCVGASREDVSEVIDDFLEAGVRSFLALRGDPPKDQPD
WRPPAEGVHSSIELVHLLREVENRRCAQDPSAALRGAARPLTIAVATFTNGNPAAGTTRT
QEVHRLLEKQEAGASFAITQLFYEADSYTDFVAEARAAGVTIPILAGLLPTTEPQRLRRV
EELTGVVPPRHLLEALDALPDPEAQHAYGIAYSAELAQRVLDAGAPGLHVYTFNKYRPAL
DLLEGVNLGGTTSSDDGVDLARRPWVPGIPSDAPLSRTGTTT
>A0A2E1QR11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MNNIYPKNVNFSYEVFPPQDISNNSKLVEKINALTYKPSFISVTYGAGGSNRDKTMDLVR
RIHQDTDIDVAAHLTCVDSSIRDTMSLVEYYLKIGVNKILALRGDSTNNISKQYEAHPRG
FQKTGELIKAIKKLSDIQVYTAGYPEKHPDSADLKCDIENLKDKINSGSNDIITQYFFDN
NLFYSFRELLTVNKIGANLIPGIIPITNFQKIREFSIKCGASIPKTFEVIFDDHFSNXNN
EEQLEIXLSIIADQAKDLIQNGINNLHIYSLNQISLMDQIINKLNIDNVK
>A0A2A4P428|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MKVIEHINNAKDPIFSFEIIPPIRGKSAQEIIDIVKDLEPFNPPFIDVTSHPAEAYYEEG
SDGEIKRRVRKKRPGTISICGIIQNRFKIDTVAHLLCRGFTREETEDAIIELNYLGIHNI
LAVRGDETNYKKPVHSGRTVNVYASDLVKQLNDLRSGNYLDEILNADPVDLCIGVGGYPE
KHFEAPNLKKDIEYLKQKVDAGADYIVTQMFFNNADFFNFRDECRMAGIKVPIIPGLKIL
NNPKQLTSIPKNFFVNIPAELSEEIEKNLKYTREIGVEWCVKQCEELLDSGLMTIHFYIM
SGAKAVTKVLKKLNK
>A0A3N9NU47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
YDLDSIQLIYTLKTMRDAKTFLCGDEIRNSKKSPIMEPRIFIGGAANPFGDPFEFRVIRL
AKKIKAGVDFIQTQCIYDMERFEKWMTMARERGLHKQVKILAGVTPLKSARMAMYMRDHV
AGLKIPDTYIERLNQAEDAAAEGINICVEQIQHLRTIEGVAGVHIMAIEWERRVPEIVER
AGLLPRPEVK
>A0A516GN98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Formosa sediminum|TrEMBL
MKVTDHIKQANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVD
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VVALRGDARKDEPYFKPTEGGNHYASELVTQISNLNKGKYLHDDIKVEHNYDFCIGVAGY
PEKHMESPSLNTDLKRLKAKVDAGADYVVTQMFFDNKKYFDFVDKARAIGITVPIIPGIK
PLAVKRHLQILPQVFKIDLPEDLIDAVEGCKDNKAVREVGIEFAIQQSKELKAAGVPFLH
YYSMGKSDNIKAIASAIF
>R6J039|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia muciniphila CAG:154|TrEMBL
MHLRERLQSGAGPSLSFEFFPPKNEQAASALYQTIRELEPYRPSFVSVTYGAGGSTRELT
REVVLRIQHESRIPTVPHLTCVGHSREEVWNILDQYARAGVRAVLALRGDPPRGAKDYNR
DSDVFRHAADLVTFIREYNESGRHPDPDGFAIGVAGFPEGHPATPNRLREMDFLKAKVDA
GADYICTQLFFDNHSFLDYRERCLLAGIKVPILAGIMPVTSLSGMNRMAELSGGTCFPAR
LLKALKRAGSNPDAIQEVGIQYASSQCAELLDSDVDGIHFYTLNQSRATREIYRNLGLKD
SLQLLEHGEDK
>A0A2E3TQ91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichales bacterium|TrEMBL
MKNLLTHLQHPNSTKDYQVEDEPDAIKISEYWGRRIDQNQKPKISFELFPPKSDSANKLL
KKTHQKLSEINPDYFSVTFGALGSSQNDTFDTVADLSEDTKIPIIPHLTCVGTDKKQVTD
LLDEYIAQGVSQIMVLKGDYPKTIIKKGDFNYANEMVEFIKENYLDINILVAAYPEKHPH
SNCISTDIDFFVNKVNAGADKAVTQYFYNIDAYLHFIEEVQKRNIDIPITPGIMPITNYD
QLIYFSKTCGAEIPAWILNKLKLYKNDLNSLKEFGEDVVSEMCLKLKDNGVSSFHFYCLN
KAEPTLSIVKKIT
>A0A854M7Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter indicus|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDKDIQHFVEKVNAGANAALTQFFFNPDAYFYFV
ERIQQAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVLKFCERLIAGGAPSLHFYTMNNTEPTRQLVTDLGLA
>A0A7C5EUJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MAASLMDRLGKSALVGSGAVGTCLRRTGDSPSGMPVEALNLRNPGAVVSLHESYVEAGSN
ILVTNTFAANRPSLEDAGLADSLAHINREGVRLAREAGGQDALVWASVGPLSLGLGLADF
SDGALRAMFREQCEALSGADAILLETFVDLREAAAALDAAGATGLPVVFQIGNVGGGRDR
LQRLGELADLAAASGVAAVGSNCQQAGDIIETAAFLLGRTSLPVTAAPNAGHATVERGVV
IYHFSPEDLKKAGIVLWEMGVAVVGGCCGTTPDHIRALAQAIGGRPVAPRRAPAVTARKS
APGAAAGPRAGNPVRELMKSDRFLVSVEIRADRRSALEGIIAGASSIAAAGADLFDVPDN
PAATVGRDAMVVAARLQSALGRPAFPHKSVVQANLLQLHSSLIGCWDLGLRAVLAVTGDP
PSLGHLAGMARLVTDIKSSVELLRLIRELRNGRMINGEEIGDPPDLCAGCAVGQPTPQQL
SWLKKKVEAGAEFAFSQPIFDVDTFLRLKDGTDGLGLRVFPGLMPLTSRRGAESLASGRV
PGVRVPEQVVEQFRRYDEPADQRKLGLDLARDLAARMIEDGASGIYLIMPFGRGCYEETA
SLVSHMRKVASSKTASPR
>B1L3C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Korarchaeum cryptofilum (strain OPF8)|TrEMBL
MEIGIEIVPSNLPKFLRSLSSVIGHANFISLPECPFGRPLPSPLILSVVAKGLGLEVIPN
YRVMDRSELGFISEIMALSEVGIRRVVIVRGDLPSIGMPTSLNPVRAIELIKEHGIDIEV
GVATYTKPNEALRAKIEAGADFVVTQPIQDVGELSELLDFLGDIPLYTMIMPGMEDLDLN
VLREMGLNEVRNVDYKALLQDISRTKVRGVIISSPKGVSKALEILR
>A0A7V4J1K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MKELGRTILIGSGAIGTSLRKLVSAGNDPVELLNLRDENDVYNLHKAYLNAGADILITNT
FSANSLALSEIGMESKCRLINEKGVAIARDAAEDKAMVWASVGPLNLGLRIEDYSDEQLF
AIYQEQCSYLKDADALVLETFVEPREASAAVNAALTIKLPVIFQIGNTGRGPSQWQRIDK
LLEIATRPGITAVGVNCRHPKDILKVFLYISAKTNLPLTASANAGNARIERGVITYEFSP
SDMESIGRSLADMGASVVGGCCGTTPEHIKALSGAIKGMTVVHKKTIEIVGESRTGEIKS
QGAVPNKIRELMRSDEFLISVEIRADRTQTMNEIVAGARKIAAEGADMFSVPDNPGAMVG
RDAAITAYRLQKETGIPSIAHFAATQANMAKIHSMIIGFWDLGLRAILAITGDAPSMGHL
SGISHRVTDIRSSVELMRLIRQLREGQIINGEKVADSPDFCVGCAFGQLNEPQKKWLEKK
VGAGAEFVFSQPIFTNEACKRLLDFFGGVPVRFFPGVMPLVSKKNAEFLAAGHIPGIVVP
SEVVESFSHFNMPEDQRKFGIEKAIELAQFVVENADGLYLIMPFGKKCYDDAAEIVAACR
KR
>A0A0E3SQ59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanococcoides methylutens MM1|TrEMBL
MLSTFNDALNSDRFIVTAEVAPPKGTDISAVLEDADLIRGWVDAINITDNQRAVMRMSPV
AVGKLLMDAGHEVIVQFTCRDRNRLALQSDILAASALGISNLCVMTGDYPTKGDHTGTKP
VYDLDSVQLLSVITKMMGGHDMAGNELAGAPSFTVGAVSNTDAARRMQMIKLKKKIDAGA
QFIQTQAVYDVEGFGEFMDSFPDSDVPVLAGIIPLRSAGMARFMNGNVPGIRVGDEMISR
MEDAEDPVQEGLEIAAESIRELRKMCRGIHLMPIGGNSNTTKLLEMAGISALQ
>A0A6L5QAJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella aquatilis|TrEMBL
MDNPNFSIEFFPPKTAEGAEKLRVTRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILA
AGEQAAPHLSCVGGTRESIREILSEFKSHGIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGDWFHIEVAAYPEVHPQAKSPQDDLLAFERKIKAGANAAITQYFYNADAYFQFVE
QTRKLGIDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSVSIKAFGLDV
VTALCERLLQGGAPGLHFYSMNQAAATTALWQRLV
>A0A4V6I2U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter jaachi|TrEMBL
MEINIESLVAKLHSKEAFLSLEISPSLSSRLDVEFINELKSLKGVDGFVCTDSPLARFKP
SSILSSIKFQNALQKPVICTLSMRDRNSLALCGDILAANEMGLRAFLTLTGDSIKNGDCV
GAKGVFEDNSLKLGAIIDGLNNGIAVNGKPLKEPIERIYNFQVINSYANNLQSLKHKIRK
KLSSNRLSALFTQPVYSLEGAEFLLKSLEEINAEYELDCALVLGFFPVMSYKIALFLRDK
LPGVYIPDTWVDKLHTAHAKGIVEEQKVGLEMSLSLFESLKKLHNKFHFMSANKPSLLEY
FRI
>A0A8C2L0T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
DWEEVEGNGGKAFLCYYSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRWFSL
EFFPPRTAPGAVNLISRTNITPTLHRSGFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMM
IASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGKDWVEEDGG
FNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIITQLFF
RAETFLKFVKDCRAIGISCPIVPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDND
AAIRSYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAV
SAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSK
SPKEALLQMWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDEL
EKVNCRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKK
YEPRVNYHIVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALW
IEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQE
D
>A0A7C6UGF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MAPPTIREILATRRQPTLSLEFFPPKDNDGFERLELALQRMLPVHPDFVTCTYGAGGSSR
ECSFAAWELLRRMGFRPVVAHLTCVGASRADLIEQIDRIYAMGIRNIMALRGDPPRGETT
FTPAPDGLAYASELVHLIKSRHPDICCGVAGYPETHPEAPSLAADLQYLKQKVDAGADYV
TTQLFFDNSVYHRFCDAAAAAGILVPILPGLLPVASLAQLDRFLAFSRATAPDTLRAGLS
AADPEDARRFGIEWLARQMDDLITRDAPGIHLYILNQARTILDPRISESLARWRTTPLNP
TPPAATPPPL
>A0A0S8KAH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium SM23_81|TrEMBL
MSRLREELEADRFAITAEIVPPKGTNVQETITTARSLWKFVLAININENPHAVMRMSSLA
VSRLLVEARMEPVFHVTARDKNRLALQSDLLGAAALGIENVLVISGDHQSLGDHKEAKPV
YDLDSVQLLRMITTLMSGRDLAGGALDGTPVFFPGAVVNPQGDIPELEIIKMEKKAAAGA
QFFQTQAVYELESFAAFMDQIKHLETKVLAGIVPLKSPRMGRFMNEKIPGIRVPDELIER
LEKSSRKEEESLAIARELIAGCRDLCHGVHLMTIGWYDKVERMLADII
>A0A258MSG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. 35-46-11|TrEMBL
MELSVEFFPPKTPEGESKLHLVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVRDMLKQYQALGVKRIIALRGDLPSGMGQYGEFHHANELVEFIR
AETGDWFHIDVAAYPETHPQAKSPATDVDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YDLGVTEPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDTASIRAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLSLNK
>A0A1B1S9P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculum intestinale|TrEMBL
MKVTDIIAARQTPGFSFEVLPPLKGRGINQLFKNIDILCEFDPLYINITTHRSEIVFKDT
SDGLYRRVSERSRPGTVAVAAAIQQKYGIPAVPHMICSGFSKIETEYALIDLNFLGITNL
LLLRGDKAKHESRFTPNADGHAHASELQQQVNDFNRGYFIDGTKMDIITGETFSYGVAGY
PEKHEESPNPDIDLQYLKLKVDNGADYIVTQMFFDNEKYFRFVERCRNAGINVPIIPGLK
PITTMSQLNLLPKVFHVDMPSDLANELMKCTSDAQAKEIGVEWCTMQARELIAHNVPSIH
FYSLNATRSVERVAHTVY
>A0A344KLR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio campbellii|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDATRDELIDIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEAHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A430FAS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium castoris|TrEMBL
MSIFSLEIFPPKRTAPVGTIYDTLDGLQGLEPAFISVTYGTGKSVDRTATARIANTVRAE
YGIPAVAHLTAQYLDEAGAEEALDLFDQAKVAGVLALRGDRNPEREPANVFRHASDLAAF
IRERRPDLPIYGACYPEKHPQAASLDEDIDNLKRKVDAGVTHLISQLFYDDEDFLRFRDK
ARAAGVDVPIEAGIMPVANCASVRHMAGLCGSRIPEPLAAMLDMWGHDPASLKEAGIIYA
SEQIRDLTARGVDGIHLYTMNRPCVTRRIWANTKAFFG
>A0A3N6FG22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ADI95-17|TrEMBL
MRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKA
TEQIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWIEHP
QGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDKCRAGADYAITQMFF
NPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLDRFAQLSNASFPSSLKERILAAKDDP
AAVRSIGIDFATQFCARLRSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A7C3H1E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MSDNGYIVGSNLEKALKAGYFVATGELGPPQSADRHEIERKANLLRGIVDSVNITDNQTA
VVRMSSISVAVMLMEQGIEPNIQMTARDRNRIAIQSDLLGAYALGVRNLLCLTGDHQTFG
NHPQSKNVHDVDSISMLQMVRDMRDKKIFQCGDPIKGQEPRFFLGAAANPFGDPFEFRPY
RLGKKVRAGADFIQTQMIYNVPKFQEYMRRVVDLGLHEQVYILAGVGPIRSLGAARYMAT
KVPGMEVDPEYIERMRNATKGLPSIKEIKAMDNPEEAKAARRARKAASEKEGIQICVDII
NACKEIEGVAGVHIMAIEWEEAVDRIVQACQIGPKYDPARQ
>A0A7G2RYS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp|TrEMBL
METQKQFKRRFSFEFFPPKTDKGWEKLQGVRNTLAEVDPDFFSVTFGAGGSTRDRTVQTV
LDLHKRGVSTAPHLSCVGATRDSIAELLDVYRDNGINRIVALRGDMPSGMGAAGELRYAN
ELVSFIREYSGDTFNIEVAAYPEFHPQARTAEDDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCAKLLAAGAPGLHFYTLNQAEPSQSIWKNLGIGEREKIAF
>A0A7C5E8X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MHIAEILKRPGPHFSFEFFPPKTEEAAQALFEAIRDLVPLAPSFVSVTYGAGGSTRELTR
ELVIRLQRETHLTVVAHLTTIGATREEILRLLESYVASGIENVLALRGDPPRDQPDYAPP
PDGFRYAAELVTFIKKHFPQLGIGVAGFPEGHPETRNRLKELEYLKAKVEAGADYICTQL
FFDNHVFYDFCERCEIAGIRVPILAGIMPITSRKGLWRMAELAAGANIPAPLLRAVWRAK
SDAEVENIGIHWATRQVFDLYDRKVAGIHFYTLNRSRPTLKIYEALGLAARETSE
>A0A7C3CGK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTLTRKEFQTKLATQSLLLDGAMGTVLHTKGAAGDKCLDALNLRDAALVAEVHRAYIAAG
SDIIETNTFGANRYRLAAYGLGDQVSQINAAAVNIARKVIDSSFKPVLLAGSVGPLGVSL
APLGRVTKQEAEAAFQEQIAALLQAGVDLLMIETMPDYAMVKAAVTVARQINADVPIITM
MTFTRDDRTLLGLNSADIARRMIKLSVDAIGINCSTGPSQVLRLAATMRAVAPEIPIAAM
PNAGYPERQASGRVGYPATPNYFAEYAHAFIAANINLIGGCCGTTDTHIAAMRHALDNPQ
PSTITQPRIELIREQDRVSVAAEPPTKLKQALQAGTFIATVEMRPPKGVSAKKMLASAEM
LTASGATFLDIADVPLARMRMGAWAAAYIIQKKLAVETILHFPIRGRNLLRIQADLLAAH
ALGVRNLFVTMGDPARIGDYPDALDHHDIVTTGLIKLLKEQMNAGLDKTGARLDQPTHFT
VGTATSLTPSSPRKEARLLNKKIRFGADFALTQPCFDAKQAREQLELYRREFGKCELPLI
VGIQPLFNGRNAEFLHNEVPGIIIPERYRQRMHAAHQPQVEGVKIAQEIIQEIRDVVQGV
YIVPAFGRYDLVADVLEIL
>A0A7C1WSC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MKIEDLYRREKPVFSFEFFPPKTDEAARDLLRTTADLRELLAPDFISVTYGAGGSTRGRT
IELVSRIQGDLGIPSMAHLTCAGHTKGELSDILDRLARRGIENVLALRGDPPRGETEFRP
AEGGFTHASDLIGLAAEHGGFSIGGACYPESHPESPNFEADLRWTRYKVDCGVSFLITQI
FFDNEDYFRFVDRAHEAGIRVPIVPGIMPITNVAQIERFTKMCGATIPDDLNRRLQRFAD
DPSTVMAIGIEHAIRQCRRLIESGVPGAHFYTLNKSHATRSIL
>A0A7C3NBW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MKYRFLEQLDNQRLLSDGAMGTMIYAKGIPFERCFDELNISQPALVADIHRSYIQAGANV
IQTNTFGANRYKLAEYGLGQKVKEINQAGVLLARRVVDAAFKEVFVAGTVGSLGIRLAPL
GRVTASAAYAAFLEQIAALVEAGVDLIIFDTFSDLAELEQAALAAREVSPEIPLVAQVTF
TEDGRTPLGHTPEIVAARLSQWPVDVVGVNCSIGPAGVLKVLKNLAEFLPANTRLSAQPN
AGWPARVGGRIIYPATPEYFGEYALAFAEAGVRLVGGCCGTTPEHITHMRAALDDPTRHA
PHLLRLPGDDGGSAGPARGLQPTYLAQRLAKGEFVVTVEISPPKGFSAERVLAGVSTLKA
AGANLMNVADSPRARMRMSPWAMCHLIQNQLDIETVLHFPTRGRNILRVQGDLLAAHALN
VRNIFAVMGDPTSIGEYPNAFNEYDVVPTGLIKLLKQGFNKGLDHGGEPLAQSTNFFVGC
ALNLTPADPAQEIKLLRRKIESGADFALTQPIYDAAQAQAFINRYEAEHGPWTLPIIAGV
LPLYNGRHADFLNNEIPGMNVPDEIRRRMQFAGEKGATEGVAIARDLITQLRPFVQGIYL
IPAFGRYDLAADVIEVVSEAAPPA
>A0A429XY88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Siminovitchia acidinfaciens|TrEMBL
MNLLDSLKEKIMIGDGATGTLLYSCGVDRCFEELNLTHPDDILHVHKEYLQAGADIIQTN
TYGANYIKLSRYGLEERVKKINSEAVRIAREAAKKDAFVVGSIGGIHGARFHTKLKDEIK
RSFREQLYCLLLEGVDGLLMETYYDIDELTSVLKIAREVTDIPIITNISMHEPAVLENGM
HLSEAFNRLEALGADVIGVNCRLGPYHVLKALEAIPIPKKAILSAYPNSSLPEYRDGKLL
YNSEPEYFREYALHFRNEGVRLMGGCCGTTPEHIKALKAGIKGLDPLKEKEVKTPPRVII
SEEKHHEGLTLYEKVKAGRSIIVELDTPKHLDTEKFFEGARALKNAGVDGLTVADNSLAS
PRICNKTMASLVKRDIGLSSLVHITCRDRNLIGLQSHLMGLHTLGIRDLLAITGDPTKIG
DFPGATSVFDVTSFDLIKLIKQFNEGISFSGKSLKQKTNFHVAAAFNPNVHNIGKSAERL
AKKIQYGADYVLTQPVFSKEKIIETWEETNYIDAPIYIGIMPLVSARNAEFLHNEVPGIK
LSNDTRKRMSAAGSPEEAVQEGLSIAKELIDTAVQYFDGIYLITPFIRYELTVELSKYIQ
RKTKELNAVKASQLVLSK
>A0A7V2XSS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSRSDLLAALSARVVVGDGAMRTALYGKGVPFSACFEELNAARPDLVQEVHRGYVEAGAE
LLGTNTFQANRYRLAAHHLEGRSRELSRLGARWARECARPGLFVAGVVGPLTDPGRASRP
GRQERRIAFAEQIDGLLEGGCDAILFASFSDLEELLLGVEVAKLRGAVVIAQLAFWDRDR
TAAGVDARAALRALEGAGADVVGANCGQGPRGLLRVVEMLGRYARVPLSVFPNAGYPDFV
DGRYTYRSSPAYLASMAERLVSAGACLVGGCCGTGPEEIRALADRLKGVRPVARASVEPA
EAPDVAARVESDGGSRTRLARALGRRPLVVAEIDPPKGLRIEPRIDRARRLVAAGADAIT
VGDSPLAIPRMGNAIFASHVMSAVKTDVILHVACRDRNRIGLEAELMAAASIGVAAVLCL
TGDPAGIGAQAGATSVFDLDSVGLIRIAAGMRAGIGALGAPLDRPADFAIGVSFNPNARY
LDDQIRRLEKKIEAGAQFAMTQPVFSAKGVERLADAVRALRIPVLCGVMPLTSAQDAEYL
HGEVPGIAIPDHVRERMRRVPEERSGAEGIALARELVEAAVANGMGVYLVAPFGAAGGIE
TLVRRASDLSRSAAPVPTGDDRDPEREVQIEE
>A0A3C1W9C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MQHTTHISEILSQGNPSISFEFFPPKSAEASDRLFSTIHDLKQLNPSFVSVTYGAGGSTR
DLTHKLVLRIMEETTIPAIPHLTCVNHSRVEISEILSGYANAEVPAILALRGDPPEGTPD
YNRAQDAFCHAADLVSFIQNFNREISNPRKKFGVGVAAFPEGHPDTQNRLKEMDHLRQKV
DSGADYICTQLFFNNYSFLDFRDRCRLAGIHIPIIAGIMPITTKSGMVRMADLAAGVHFP
ALLQRMLLSAKDDPVAFEKAGTDYATSQCRELLAEGVEGLHFYTLNRSSATTQIATALDL
GQK
>A0A3M1SEW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSHKQAGGRLERELAGEKFIIGAEVVTTRGYPQHEQAIPSVALARALLEDERIGWISITD
SPGGTPMLPPDWLAGFFPEQRERIVVHLTCKDLNRNALEAYAWRLAAEGIRNILALTGDY
PTAGFGGAPQPVFDLDSVGLIYLLSAMNRGLEVPGRGGKKQTLPPT
>A0A3C1Q0D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MAILSSLRASRPTLSFEFFPPKNDLGSEELLETVNELDKLDPAFVSVTYGAGGTTRERTR
EVVQRIIQDTNVPTIPHLTCVGHTKSEISEILSQYSADQVGTILALRGDPPRDQPNYDRE
GDDFKFAGDLVAFVKENSNEFEVGVAGFPEGHPETQNRLTEMDYFKSKIDQGADYICTQL
FFDNHDFFDYRERCNLVGIDLPIVAGIMPITTISSMKRMADLAAGSRFPAKLLKRLSVA
>A0A2N0LCY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G3|TrEMBL
MVTVLQKLAESNGRPLFLCDFSPTRGADPALYDRVKNVGADFVIVAYSPGKSVRVDSTMA
AHFIRQDGEHEAIFTLACRDMNRLALQNHLLGAHLLGLENLVVLKGEELSEKDLTLTKSV
NDVTPTQLIRDIVGLNNGIDFRERNLRAPTTFCIGASFDPGQSDIKAEANLAHQKVRAGS
DFFITQVLYDPTLAKRFLEVYNDLTGDEFPKPIFYGLQILEKEGISFGDTPERITRELEQ
GRPGIEIAFEHLQNCRENGLTNFYLVPPILKGGRRNYEAARQLLEMFNQISPLGSR
>A0A2M8M2W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces carminius|TrEMBL
MSLGTPSTRTDRARTVRELLASGERSYSFEFYAPKTEKGERVLWDAVRRVEAVSPTFVSV
TYGAGGSSREGTVRATERIATETTLTPVAHLTAVDHSVAELRNVIGQYADAGIRNMFAVR
GDPPGDPTGEWIPHPQGVMYAADLVRLIKESGDFCVGVAAFTGMHPRSTDVESDTRYFVE
KCRAGADYAITQMFFHAEDYLRLRDRVAAAGCATPVIPEIMPVTNVRQIERFAQLSDAPF
PPELAERILAFEHDPAAVRSLGIEYATELCARLMSEGVPGLHFITLNRSTATLEIYENLG
LHQRGR
>A0A3D1KS06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibacter sp|TrEMBL
MKVTDHIKQAKGKTLFSFEIVPPQKGQNIQELYDNINPLMEFKPPFIDVTTSREEHLYIS
KENGLLEQKITRMRPGTVGICASLKYKYNVDAIPHVLCGGFTKEETEYLLVDCHYLGLDN
VMALRGDAMKHEKYFAQTKGGHQYARELVSQISDLNKGKYLHEIVETLYKPDFCIGVAGY
PEKHMESPSLEADLRRMKEKIDAGADYVVTQMFFDNQKFFDFVEKARAMGITVPIIPGIK
PIAIKRHLQVLPQVFKLDLPEALISEIEKCTNNEQVRQAGIEWSIAQSKELVAKGVPVVH
FYSMGKSDNIKAIAKEVF
>A0A1B3W7V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas sp. JM171|TrEMBL
MTQISFEFYPPKNDQQRAQLDRTAERLKAHDPEYVSCTFGAGGSTLRYTPETVRRLHQEH
GFVAAPHLSCVGGTREEIHDLLQLYRAIGCNRLVALRGDMPSGMGQIGEMRYASELVEFI
REATGDHFRIEVGCYPETHPQADDALADIRWFKAKVDAGADAAITQYFYNADAYFHFVDA
ARAAGIEVPIVPGIMPISNFSQLRRFSQSCGAEIPRWISKRMMALGDDVDAIREFGADVV
AAMCRRLLDGGAPGLHIYTLNMARPTQAILSRL
>A0A3L7QXS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MHLADILARDTLTLSFEFFPPKSDAGWDGLFRTIAEFEPLAPSFVSVTYGAGGSTRDNTH
RLVTRLRRETTIEAVPHLTCFGHTKDDIRIILEGYAVAGVSNILALRGDPPTGARFLPPG
DFPNAADLVRFLKREGERLGVNGGRGFGIGVAGFPEGHSETPNTLLQIEHLKAKVDAGAN
YIVTQLFFDNSAFHDWRARCELAGIRTPIIAGIMPITSVSGLKRMAELAGGTRFPASLLK
AIDRCKGNAEAIENAGIHWATEQCRDLLDLDVRGIHFYTLNKSDATKRIYRTLGVRPSP
>A0A350EZE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRPLREVFREKRAAGQPVISFEFFPPKTPEGDASLLERTIPGLKAFRPDYCSVTYGAGGS
TRDKSLMIVDRIQKEHGLTALAHLTCVNATREEIGEVLAEAQALGVKNILALRGDPPAGS
DVFTKTEGGFEYSYELVEYLRDLGDFSIGVAGFPEGHIACKEGKHVDWDRLKHKIDCGAD
FVITQLFFDNADFYEFRDHLTKQLGVKVPLVPGILPVLSAGQAKRFTGLCGARIPEPMLQ
RLNELTDDDAGAAEFGVEHATAQCRDLLANGVVGIHFYCLNKLPSCAAVLRNLNLDGHTG
D
>A0A4Q5QTN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIDHIRGAKDTLVSFEILPPLKGKTINSIYDHLDPLMEFKPSFINVTYHRSEHVFKKK
ADGSFDKVEVRKRPGTVGICAAIMNHYKVDAVPHLICGGFTKRETEDALIDLNFIGVDNV
LVLRGDAAKNETVFEPELGGNRNAFDLLKQVNNLNNGIYLEDDIRDGFRTNFSIGVAGYP
EKHFEAPNLDTDLAYLKAKVDAGAEYIVTQMFFDNSKYLDFVTKCRAIGIDVPIIPGLKP
LTTKKQLSVLPRTFHVDLPNDLINEVMKCKTDADVELVGGEWLLQQSRELKAAGVPVLHY
YTLGKAKLIYKVVKDL
>A0A4Q3UII0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
LFQLLDPLMELKPSFINVTYHRSEHVFKKTAENTFEKVVVRKRPGTEAICAAIMNKYNVD
TVPHLICGGFDINETEDALINLHYLGIDNVLVLRGDAAKNESTFEPEPGGHRYAIDLLNQ
VCNLNSGVYLEADLKNSAKTKFCIGVAGYPEKHFEAPNMDSDLQYLKMKVEGGADYIVTQ
MFFDNEKYFSFVKACRNIGITVPIIPGLKPVYTRKQLNVLPKTFHIDIPTELSTEMNKCQ
SDESVAQLGAEWLLHQSKQLKAAGVPVLHYYTIGRPELVADVVRKLV
>A0A2U1BF43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agathobaculum butyriciproducens|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTSSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>A0A8J6N562|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfaltia bathyphila|TrEMBL
MKSGSNLEKVLTSGQFAVTGELGPPKNADAEVIRTKARLLKGCVDAVNITDCQTAIVRMS
SIASSVILMEEGLEPVTQMTCRDRNRIAIQSDLLGASALGMKNLLCLTGDHHKFGNHPNA
VGVFDMDSIQLLQMVKNMRDEKVFQCGEELKGTEPTFFLGAAANPFADPFEFRALRLAKK
VVAGAQFVQTQLVYNLERFTAWMQAVRALGVHEQCYIMAGVTPPKSIGMAKYMKNNVPGL
DVPDEVIVRLKGARDAKKDVQEEGINICVDIINRVKEIEGVAGVHIMAIEWESAVPEIAK
RADLLPRPG
>A0A6P2JXH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia arboris|TrEMBL
MSSLKQALNDGRFVCVLEVVPQQSPSRLAALEPIVQRGHLAGWPLLPAFADRVGLHSDLS
PLEAAEALGNPASSLLHFSGKDRERADLLLQMDSMKALGVEQLLLLSGDRLPGHHDQAQV
RYLESVPALQIAREHGPDWLLGAALNPFKYREEEGGAQYLKAQKKLLAGADFLTLQLGFD
AAKHIEAQTWMRAQASMKPMLACVMGVTDKCAALLQAVPGIVITESMRMLLGREQRVSQA
YASARSVERLALQILGLQLMGYAGAHVSGVHTLDELLSLEQAITEQRDSVTSLTEWSERW
RASWQLPGVPQVSFTPESGAWEMGQSDVTATRRERLRHRLLSSTHDRFFSRTGWLGRAFG
WSVTRSIWKVGMAANALHAIERTIKRPLVGCDTCGCCRLQDTLYVCPETCPKGLANGPCG
GTRLNRCEFGDRECVHSVKYRIAKSADQLAVLAQTLIPCIEADNRHRSSWPEWFEPEDPT
QGAESNPREWKPARRPLRRRK
>I3RE25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrococcus sp. ST04|TrEMBL
MRVPGCPKDLLNGPCGGALNGICEVDGRRCPWFSVMERFELLDGAPLLVEHPIIIEMERK
YEGDVKIRRSKFISNLEKGKALAVEFPLRVFEKGIREFKEVGDIYTVPDNPLGYPHISPT
ALATWLKIRGFSVMPHLTAKDRNAVAIASEFRTAIEFGFEGVLITTGDWPGFMIQSKPVF
DLDSANMIKMARLMFSGILPTGERISIDERPFIAGTMNPNYPEKVEGKRLARKIIAGVDL
VFTQVVASIKAVNRIPKIMEEAKKFSTREVPVVVSILYPMTKELEGTLKKMGIETGNTFE
EIIQEISSLELGGVNLIVFNDSNWDSLLEEAIEILKEVIL
>A0A7Y6F312|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces odorifer|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A3P8T4I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amphiprion percula|TrEMBL
MVNQVQRGDGNCQSCKSDSSGSNSGGESSKESSRCSTPVLDADRSDRLRDKMRRRMESRD
RWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQTKEKITDYLTKAKRLGLKNIMALRGDPLGEDWEEEEEGFNYAVD
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGADFVITQLFFRADTFL
KFLEDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEDITKVIEPIKDNDAAIRNY
GIQQAVEMCRVLLESGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELMSEESVNEIFTCYITAQPNRRGHKVLCLPWNDEPLASETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPVSFMSWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDVPPELLNDGAVSE
>W9YGS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capronia epimyces CBS 606.96|TrEMBL
MADDDRLPTLFASLPPSSNYFSLEFFPPKTSSGFSNLQSRLARMAAALRPLFVTVTWGAG
GSTATKSLELAEVCQRQLGLTTVLHLTCTNMKRSMVDEALESAKEVGIRNILALRGDPPR
EEYRDTSEGLATDSNEEFVWAADLVRYIRRQYGDYFSVGVAGYPEGHADESNPEAGKQSV
EHDLPYLAEKVAAGADFIMTQLGYDINAYQAYEKRLRGYVDTDGNKLFATIPIIPGLMPI
QSYQIIKRITKLSHAKIPEDISRRIEAVKSDDEAVKRVGVDILSELVDQIKALPQPDGVP
RGFHFYTLNLEKSVAFIVERTGLTPPISEPEPESSPGDLSDSDAIANDEVKTASSTLSNG
AAAETGIFVPPTKSGSLAKRRTSSINAQPHNRVILEEKARRQAEKVAAAAATLKQHVAPD
RGTGIPASDPTRRHNLMISEGQGALGREATWDDFPNGRWGPSHSPAFGEIDGYGPTLKVG
PITARRLWGQPKSRQDVTELFRRHVVCELEAVPWSDEIDVDSGAPAALRAETDVIRNELL
ALIEKKGYWTLASQPAVDGVRSDDETFGWGPPGEGFVFQKAFVEFFCPRQEWEHHLRPLL
IKYGSEQVGWLKTDANGVFESSEQLEAETQRRSSTLGVNSHQVTPSTGTNGNGGGGGGVN
AVTWGVFRGKEIVSPTIIEAESFRAWGEEAYSVWSEWRKCFPRGSQEEQFLERMRQESVL
VNVVGQNFIGGHGGHGAELWKILLQDEIQESRDGGE
>A0A0Q4Y5T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodoferax sp. Leaf267|TrEMBL
MSTSTRADFPVSYEFFPPKTPEGVAKLRGVRQALYARQPLFCSVTYGAGGSTQQGTFGAV
AEILAEGVDAASHFSCIGATRETVRTQLAELRAMGVKRLVALRGDLPSGYGAGGEFHYAS
DLVAFIRAETGDAFHIEVAAYPEIHPQARSPEADLQAYAAKVRAGANAAITQYFYNADAY
FRFCDDTRRMGLDVPVVPGVMPIISSTQLMRFSDASGAEIPRWIRLRLQAFGDDTASIKA
FGLDVVATLCEQLRAGGAPGLHFYTMNQSVATLELCRRLAL
>A0A2K8L8Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariprofundus aestuarium|TrEMBL
MKLSKILSSATRPLFSCEFFPPKTDKGEENLWNCLRELQTINPAYASVTYGAGGTTQDRT
KGIVTRIKDQTGLSPVAHLTCVGASKDQLAELLADYRAAGIENILALRGDAPEGMDRFKA
VAGGFSHATDLIAFLREQGDFSIACATYPEGHPESAGGVADDIRYLKIKQDNGADCAITQ
YFFDNDAFFRFRDACSKAGVTMPIIPGIMPIGNFDQIVRFSSMCGTSIPTWLHEKMDPIR
GDLDAVAALGIELAASQCKQLLENDTPGLHFYTLNKSAATIAIHEQISHYL
>A0A7W2BMV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MGIKALDLTPGSIPMSAANAFIPASIEISPKAILAEGAPAGLFPPGTRTYITDIGNHSHL
ELATVARRLTDAGYRPVQHIAARRLNSAAELESHIKRLTQEAGLDDVLIVAGEPNRQMGP
YASTMDILRSGVMERNGIKFIAVGGHPEGNPSAPKGQDYPILREKADFQSETNAQMRIVT
QFGFDGEAFANWAWHVKAIGINLPIHLGVAGPAKMTTLLRFAAIAGIGNSMKFLKKRAGA
LTALATTPSPEPVVKPIEKFWQENPDGPVAQMHVFPFGGVNKSAEWLAQRGSWNIKISLY
GNETSSGHA
>A0A329RSN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora cactorum|TrEMBL
MGKIIESIRSGYSARADDASARPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGAERWSPVEGGLSNAVDLIKLIREEYGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIQWIADCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPEKVLTALDAIKNDDAAVRRYGTQLAVETCQRLLAAGVNSLHFYTMNLAAT
VTQVLEGLQLLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRTELWGTPQTEEDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAAIRENLQWLNSNGFLTINSQPRVNCTPSSDPSVGWGGDDGVVFQKAYVEFFVA
PEKMAHLVKVMRRDYPQLSFHALNRRGDEHRNTPLHSVTAVTWGVFPGIEIVQPTVVDSD
SFAAWKDEAFELWQTQWASAYPEGSHSREVIQHIYDTYFLVNIVDNDYANDDSDIFSIFT
RIITEAMDKEQLRARVLELETRREKMFDTLASFQSLQEELNGELRAAHSELAGVRGENLQ
LKEKVRQLQAQLALASL
>A0A2W6NGH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus silvae|TrEMBL
MKADLRTAMKQRVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
FETNTYSANFDKLSKFGLESRVEEVNRAGVRIAKELAGTDGYVLGAVGSIRGGKRTNVST
SELKRFYQQQISALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGVPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFADLGARIIGGCCGTTPDHITAIKQALAEYVPLPIAEPDPAE
SQPRIVLHENLDERAGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRALVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDPELIVKMREATKHLDIPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVTIAKELLDVATEHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFHPNNQLQ
>A0A7D7BUU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CACC 737|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPKELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A7V6ZLE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MNHFRLSRRPDIGEKIRVSFEFFPPKSDEMEERLWDTVKRLAPLSPRFVSVTYGAGGSTR
ERTIRTVRRILKETDLLPAAHLTCVGADRVEIDGVIAEFATMGVNHFVALRGDPPEGVGS
AYRPFPGGYANGAELVAGLKRHGDFDISVSAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGILPVHNIGQVVNFSARCGAHVPDWLRERFE
GLERDPQTHALVAAAVAAEQVLDLVERGVGDFHFYTMNRADLAFAICHMIGIRREVARTD
SAAA
>A0A7C3HF09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
HRDYLAAGAEIIETNTFGSNRVKLASHGLEKQAREIARAGARIAREEAGESAWVAGSVGP
LGKPLAPVGVITRAQAQAAFREQIEGLIEGGVDLIILETFGDLREISVALETAREITDLP
IIAQMSFTEEGKTIVGDKPREVARRLTDLGATVVGANCSVGPQVIYDVLEAMAAETDAFL
SAQPNAGLPRLVGGRYIYLSSPEYFAEYARRFVQAGANIVGGCCGTTPEHTAAIARAVKG
LKPVPRKRKASVLVLEKEEAAEGRRLEERTAFAQRLGKEFLVSVELDPPKGFDPTRVIQG
ALKLKTAGVDAINIADSPLARPRMSPLALAHLVHENVGIDVILHMSCRDRNLIGLQSELI
GAHALGIRTILAVTGDPPVMGDYPNATGVFDVDSIGLVHLIHLLNQGMDLTGRPTEQPTS
FTIGVGANPASVDFEHEMDRLAQKVENGAQFVFTQPLFDLSLLERFLERARPLGVPIFLG
ILPLRNYKHAEFLHNEIPEMVIPDHLRERMRKAGDRGLEEGVAIGREILLEARDEVDGVY
LMPPFNRVDMAIEVVKILEKRD
>A0A7V6ZH40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSEANPVHIDENPAGPHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSVSLLETIRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPYDFRPMHLAKKIAAGAQFVQSQYCFDVPMLKAFMDRARDLGLTDKVF
ILVGVGPLASAKTAKWIRSNVPGIHIPDSVIRRLEGAQDQKKEGKQLCIDIINEVKEIPG
VAGIHVMAYRQEEYVAEIVDESGVLKGRRPWKREARRDDRMVADRLEHILKDDITESQVD
MVKSAH
>H6LBX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1)|TrEMBL
MRITELFQRDEFVLTAEVGPPKGVELDHLIKDAHEYLKTRVHALNVTDNQSSVMRTGSLA
TCKVLKDEGLLPIFQITCRDRNRIALQSDVLSAALLGIENLLLLTGDYTTLGDHPQAKPV
FDLDSVSLIHAVKRLEEGFDLAGNAVDGAPPKFAKGAVVSPCSDSVDVQLAKMEAKVKAG
CEYFQTQGVYEPEKFIKFMEQAKQFGVPVQLGLIIPKNVGMCRYMNANVAGVHVPDDMIE
ELKADKEKTKAGDTGVEICARLIRECKDYCQGVHIMSLGWENRIPEILDMAGIAPIAK
>A0A2G3A3F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum annuum|TrEMBL
MLILASILQVDAGADLIITKLFYNTDIFLKFVNDCRQIEINCPIVLDILLCSPDGNSSPD
GHRSPNETDKKRLRHPYQSKTFNVEINFAVKIPMQAIANALRGQESENSQEALRVGYYSE
AACCKASKEEYEASVCLCGIQVCRGSYLNLTVGSSSMSTTDDSFSNLLLFAGVFEAEFTS
FSAKES
>A0A3B8VIT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHYDRATEPLISFEIIPPKRGGSIQQVFESLDQVQKFRPPFIDITSHAAEAEFIDL
GNGTMKRRVKRKRPGTIGLCAAIKHRYNVDPVPHLICKGFTKEETEDALIELNYLGIENV
LAIRGDDHAAPKPHHKDRAVNSYAVDLVRQIKAMNCGIYMEELMDAVPTNFCIGVGGYPE
KHDEAPNMKWDIQKLKDKVDAGADYIVTQMFFDNQVYFDFVNKCREIGITIPIIPGLKVL
TQLSHLSRLPKIFNLSIPTDLSDAVASDPKNAKEIGIEWSRKQCQDLLDFGVQGLHFYIM
TDPSPAVSVIDSLPVPQSTLKV
>A0A3D1H8K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKLTEYIKPGKTLFSFEVLPPLKGKSIDSLYQGIDPLMEFNPAFIDVTYHREEFIERPRK
DGGYDKISTKKRPGTVAICAAIMNKYKVEAVPHLICGGFSKDETENALIDLAFLGIENVL
ALRGDNLKNERNFVPEKNGNSNALDLIRQIADMNNGVYQDQELQNVTETNFCIGAAGYPE
KHSDAANMVSDLKFLKRKVDVGAAFITTQMFFDNQKYIDYVAMCRAAGIMVPIIPGIKPI
TTKGQLRALPKIFNMDIPEPLASELEKAKDDTAARQIGIEWCIQQCKELKSLEVPALHFY
TMSFSSATKEVVSQIL
>A0A662AWZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MQNKVIDHINKSKKPLFSFEILPPLKGKDINLIYDVIDPLMEFKPKYLNITYHREEVVYK
MHKSGLLERKTVHKRPGTVAIAAAIKYKYREVNVVPHIICGGFSKEETENALIDLHFLGI
RNLLVLRGDPLSADKEFKAEKDGHAHALELIKQIQKLNNGTYLDEELENTTKMDFSFGVA
GYPEKHFEAPNIQTDLSYLKKKIDEGAEYIVTQMFFDNKKYFDFVNLCRQNDINVPIIPG
IKPISIKRHLNILPATFQIDIPEELANEVRKCKTNEDVRQLGVEWAIEQSKELIKNNVPS
VHYYSMGKADNIYKIAKAVF
>B4WH07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. (strain ATCC 29403 / PCC 7335)|TrEMBL
MDAVSNRFRAAIKSKKFIVTAEVMPPKGANPQHMLEMADGLKDWVHAVNVTDGSRAVLRM
SSLACSALLRQAGIEPICQMTGRDRNAIALQADLMGAHALGVRNVLALTGDPLKAGDHPK
AKPVHELDSIRLLRLIRKLNEGTDYNEKPMNDGALDIFPGAAVDPQSTSWSGLQSRFEKK
LTSGAQFFQSQLISDFDKLEKFMDQVAVGCDRPILAGIFLLKSAKNAAFINRCVPGVDIP
QHLIDRLAAAKEPLHEGMKIAAEQVQAARQLCQGVHMMAVRREDLIPQILEMAGVEPQTQ
RQVASTSSAVR
>A0A351BZ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MFYDNKAYFDYVEKCRTEGIAVPIIPGLKILTLKSHLNTIPRNFYINLPDELTGEILEAK
SEHVMEIGVNWAAKQVEELLNANVPSIHFYIMQNSKPINLLMSKLKINKDNFFMNG
>A0A136N4C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobi bacterium OLB5|TrEMBL
MKVIEHLEKAKSKNKPLISFEVIPPKRGGDITQLFNVLNDVLKYEPPFIDVTSRAAEVEY
RETPQGIQKKVIRKRPGTIGISVAIKNHFNIDTVPHILCYGFTREETEDALIELNYLGIE
NVLAIRGDDLGYHKPIPEYKSQNRFAYELIQQVSNMNNGRYLEEDLLDAKPTNFCIGVSG
YPEKHFEAPNMKVEINHVKQKVNSGGDYIVTQMFYDNNVYFDFVKKCRDEGIKVPVIPGL
KVITTKNNLYTIPKNFYINIPEELSGEILEAKDEHVMEIGARWTAKQAEELLNNGAPSLH
FYIMQSAKPIIKMFNNLKL
>A0A3S2G4P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.10.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A0S9R1N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium sp. Leaf289|TrEMBL
MTDGPAPTSSRSLLEDLRHPRPCVSFEFFPPKDDAGEEVLWRTIADLEPLQPTFVSVTYG
AGGTSQERTVRVTSRIAEQSRIRAIGHLTLVGQSRAEIEQVLKQYASAGIHHVLALRGDP
KGGPREPWEPHPGGMDHAIELVELARDLGDFSIGVAAFPEGHPDAGGRDPDADVLVAKHR
AGAEFAITQFFFRVQDYVDLVERTRARGSDLPIVPGIMPILNFGQVARMAELSGAEIPRE
VLDVIEPVADDKDAVRTRGIELATQLCRDLLAAGAPGLHFITLNRSKATREIFETLRGEG
LV
>K9FXA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium digitatum (strain Pd1 / CECT 20795)|TrEMBL
MEKKITEKIAALPQDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKALGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRQTHGDYFCVGIAAYPEGHPADTFQDLQDPVRDIPY
LVEKTLAGADFIMTQLTYDIEAYQKFENTLRNHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIARRMEELKHDDEAVKRAGVDIVSEIVGGIRDIPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPSYSDAGDLAIEDDPASIPLDFPGRALRRRRASSINSQPHNRVVVDKL
SVHGSSQDSVHEARADSAGVPAPPPSRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTANSARRLWGHPVDSKDMSTIFRRHVSGELHMVPWSEGGAEEDGEG
LNAETELIRPELLKLIDGRGWWTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFC
SSNDYTNILKPMFAKHGHDKLTWFATNIKGDFESSLPIQPADVELDDLGSNPESVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTEAYLDTTKNDSWLVCVV
GQQFGAGTKQGSKEEEDEVKWMWRVLAGEEV
>A0A427XW97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apiotrichum porosum|TrEMBL
MKITDKLAKAEREGRPFWSFEYFPPRTAQGLQNLFDRIERMRNLGPEFIDITWGAGGKNA
DLTSSLVQVCQETIGIECCMHLTCTEMPAEKVEWALSQAKKFGCQNILALRGDPPAGSSE
WKPTPGGFSHAVDLVKYIHKNYPGDFCVAVAGFPQGHPETEDTDEARHQEMLWLKEKVDA
GADFIFTQMFYDVDIFFAWVKRVREYGITVPIVPGIMPIQNWGKFQTWVKRESIVVPPHF
YEALNPVQGDDEQVRAVGTQLVADMCRQILENKEAGIKGLHVYTLNLEKGARMLLETLDM
DPRREQVMPLPWRPSLTPSRRQESIRPIFWANRVQSYLSRTSDWDEFPNGRWGDSRSPAY
GDLDGYPVAINVNAAEAQTLWGHPETREDIAELFAKFCRGELAKLPWSSAPPASETSVIT
EQLARMNERGFLTINSQPAVDGAPSDDKVHGWGPAGGYVYQKAYLEFFVAPELLSQLIRR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGCQWANLYPEGSASRALISQVMDESYLVNIVANDFKDGQTIFEPFLLDQPANGN
>A0A0M8VNB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL WC-3618|TrEMBL
MAFGTASTRTDRARTVRDMLASGKTTYSFEFSAPKTPKGERNLWNALRRIEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVSDTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPMADWVPHPSGLTYAAELVRLIKESGDFCVGVAAFPETHPRSADAETDVTHFVD
KCRAGADYAITQMFFHPESYLRMRDAVAAAGCPTPVIPEVMPVTSVRMLERLPQLSNAAI
PATLKERILTAKDDAAAVRSIGIEFATEFCARLLAEGIPGLHFITLNNSTASLEIYENLG
LHHPQRA
>A0A537IMW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVIDHINQANGKTLISFEVLPPLKGKGIGALYSHLDPLMEFRPAYINVTYHRSEHVFKK
RGDSTFEKVIIRKRPGTESICAAIMNKYDVDTVPHLICGGFSVNETEDALLNLQYLGIDN
VLVLRGDAAKNETAFEAEPGGHRYASDLLRQVMNLNSGIYLEEDLKATSRTTFCIGVAGY
PEKHFEAPNMESDLRYLKMKVEGGADYIVTQMFFDNSKYYAFVKACRDAGITVPIIPGIK
PVYSKKQLTVLPKTFHIDLPTDLSNEILKCRTDEEVEQVGAEWLLHQSRDLKKNGVPVLH
YYTLGKPHIVANVVKQLC
>A0A5C7X3Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilus sp|TrEMBL
MNHKTSFSFEFFPPKTAEGMANLRNVRDELAVFSPEFFSVTFGAGGSTRDRTMDSVLEIQ
AAGYGAAPHISCISSSKEEIRELLQAYQAKGIKRLVTLRGDIPSGEVSAGDFKYANELVQ
FIRAETGDWFHLEVAAYPEFHPEAGSAQKDLDNFKRKIDAGADSAITQYFYNVDAYFRFV
EAAQKLGVTAPIIPGIMPIYNYTQLARFSNVCGAEIPRWLRLRLEAYGDDLPSLRAFGAD
VVTDICAKLIAAGVDKMHFYTLNQAGIIGQIIRQL
>A0A850L342|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriia bacterium|TrEMBL
MKINQHIEEAQKQEKTLFTFEILPPLKGQTIHDIYGNIDPLMEFKPPFINVTYHREQVVY
KRLTNGLLEQKVVRKRPGTVGICAALMNRYEVDPVPHLLCGGFSKEDTENALIDLHFLGV
ENVLALRGDGMQDQMYFVPEADGHTYASELVGQIVKMNNGEYLDDELANNASTNFSIGVA
GYPEKHFEAPSLNVDISNLKRKVEAGADYIVTQLFFDNSKYFEFVEKCRNAGINVPIIPG
LKPIATKKHLSMLPHRFHVDLPDDLAMSVMQAKDNLAVRQIGVEWAIQQAKELKAAGIPV
IHFYSMGKSDNIYAIAKELF
>A0A7T7XPI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Breznakiella homolactica|TrEMBL
MLVSLEIVPRDREALESGAAAALAFPRISHINVPDLLRFSIRSWEANDILDAGAGPDKPR
PFGFIPHLRAIDFDLDQPFPHREFFSSRGITKVLVIAGDPPKDPGHRTYPTETVPFIRKL
KKEMPGIEIYGAFDPYRSNIRFELDYLKEKEDAGAAGFMSQPFFDLRLLEIYAEYLEGKN
VFWGISPVLTESSRGYWESRNRAVFPKHFKPDLYWNVDFGRRVLNYCTANNFNLYLMPIK
VNLEAYLSGLFT
>A0A7X9R1T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. BL-253-APC-6A1W|TrEMBL
MDRLGATRSGRIPFSVEFSPPRDADAEARLWRAVRAFERLGPAFVSMTYGAGGSTRDRTV
RVTGDLAEETTMLPVAHLTAVGHSVDEIRAMVGAYADRGITNILALRGDPPGNPLGEWEK
HPDGLEHADELVRLVRDLGDFHVGVASFPEGHHRSPDLDHDTRYLVQKLRAGAEYSITQM
FFDVEHYLRLRDRVAACDPEQAAKPIIPEIMPITSLRSARRSLELSGSKLPAALEERLVR
AAGDGPEENRAAVREVGIEVATEMCERLIAEGAPCLHFITLNFARATSEVLSRLGIEVRS
SVPAGQPV
>A0A2K6UBD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saimiri boliviensis boliviensis|TrEMBL
MVNEARGNGSLNPCLEGSASSGSESSKDSSRCSTPGLDPDRHERLLEKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCHQRLEEITGHLHKAKQLGLKNILALRGDPTGDQWEEEEGGFNHAVDLVK
HIRSEFGDYFDICVAGYPKGHPDAESFEADVKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDVGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVCLCRELLASGLVPGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKNYYLFYLKSKSPREELLKM
WGEELASEESVFEVFVHYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGVL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHL
VNVKGENITNAPGLQPNAVTWGIFPGREIIQPTVVDPVSFMFWKVKEPGASGGSVTLRPD
AASLGNPRPCMSPPHLASTPPPDDGS
>A0A6H3JSX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT2-42-4|TrEMBL
MPHTSDPACRKIPFSFELYPPTSDAATSVLHATIERLAAAGPEFIAVTYGANGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSNAEASQLIREFLDAGVRSFLALRGDPPEGIREGEAF
LGDLGSAAELVQLIHRVQAERVPYREAVIPGLPAARTIKREREKVRIAVAAFPNGHPRSR
SATQDIDTLLAKQAAGANLAITQLFFHADHYLSFILRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRQATELARELISGGAPGLHLYAFNQHE
TVLAVLDGCGLLTPTLPSSALPAPHPVKENP
>A0A3G8WV12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. G11|TrEMBL
MKITDHIKNANGKALFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADTAFIPTKGGHCYATDLIEHIKNHNEGKFLHEDIETFKSDFCIGVAGYP
EKHFEAPNLNADFKYLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPDELTDALAHAKSNAEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTRQIARAIF
>A0A235F3C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera propionica|TrEMBL
MSIDISIEFFPPNTAEGAEKLRATRDKLAALKPAFFSVTYGAGGSTRERTFATVKEIAAA
GYEAAPHLSCIGSTRDSIREILQEYADAGIRRIVALRGDLPSGAGAAGEFRYANELVEFI
RAETGDRFLIEVAAYPEWHPQARSPKDDLLAFKRKAEAGANSAITQYFYNLDAYLYFVDA
VRKLGVDIPIVPGIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDADAIRAFGLDVV
TRLCEKLIAEGAPGLHFYSMNMAGPTTEICRRLGLHN
>A0A2L2N6J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. 'Peltigera membranacea cyanobiont' N6|TrEMBL
MHYTHSSTAFQRAVQAGEFLVTAEVAPPKGGDPTHMIQMAATLKGRVHAVNVTDGSRAVL
RMSSLMASVILSQNGIEPICQIACRDRNRISLQADLMGAHALGIRNILALTGDPVKAGDH
PDAKAVFDLEAVRLLQLIRKMNQGVDCNQKPLTDGALDLFVGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFDVLEKFMDTIAAGYKKPILAGIFLLKSAKNAQFINRCVPGVN
IPQHIIDRLAKAKDPFEEGIKIAAEQVQIARQLCQGVHMMAVKREDAIAPILDLAGIAPV
NQLVSM
>A0A1J5GED1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium CG2_30_33_13|TrEMBL
MNLREKLAAKKFVVTVELDPPKTLNLDKILREINSANFRKVVDAVNVTDCPLAKLRMSPI
ALSHIIQEKIGLESIFHITCRDRNLLGLQAELLGASALGVKNILALTGDPPEMGDYTKAT
GVYDLDSVGLVKMVNKLNNGYEYKGEELKSRTDFFIGVAVNPSAQDLKKEIKRFEEKVSA
GANFVQTQPIYDIEILERFLEFTAHLNIPKIIGIMPLKSYKMIEYLNNNLPEIFIPSVVK
ERMIGKDIGEGIKISQEFIDKIRKFKEVAGIHIFPLRDMDLVCRLLN
>A0A373S786|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. AF26-2|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>E6KQI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. oral taxon 180 str. F0310|TrEMBL
MQPQAHDDATVASAPQSESSPVPYTDDTYACPCTHDHEPTLLSFEVMPPRKPSLEAPFWK
TVDSLLGVRPDFMSVTYGAGGKDRSNARSTVHRLVADTPIQPIAHLTCVGNSTDEVVSAV
YDYLDSGVRTFLALRGDPPAGENSWEPGPGGVGSATELIHLIRTVEKRRCDAHPGEALRS
AFKPLTIAVAAFPAGNPAAGTTPAQEVERLLVKQAAGASFAITQLFWDPDVYASFVERAR
RAGVTLPIVPGILPATDPARLRRVQDLTGIEVPEHILAALSDRSDQEARYAFGAAFGSRL
FHDVIDAGAPGVHLYTFNQARPVLDILALVGVGADPDRFPASPSDTRA
>A0A562PBX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium tianshanense|TrEMBL
MDWWPARAGTNQTAWASADGGLAKFLANYSVEVTARDADATAHRLPPGGEVFVANLPQDS
HDLLVAACSRLRMAGLIPVPHIVARKIRDRREFDDLIGQLVGEAGVDRVLALGGDHERPV
GAFDASLQLIRTGSFERYGIRQIAIACYPEGHPRIGDQVLQDALKAKLAAIAESGIGARL
VSQFAFKPEPVLDFARKLRAAGISVPLRVGVAGPAHRATLIKYAMRCGVGASLRALTERR
HLVAGLLGTETPEELLTAIALAFHDDSSLRIEGVHFFTFGAPERSVEWAQDRIDGRKGFA
AATIFKHQGGIEP
>A0A4R5BZ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura darangshiensis|TrEMBL
MRRLRPDRPPTVRELLASGDRSFSFEFSPPKTDKGARNLWRAIRELESLHPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAAGVRNILAVRGDPP
GDPMGEWVKHPDGVEYAADLVRMIRSYGDFSVGVAAFPYKHPRSHDVESDTRYFVDKCRA
GADYAITQMFFRAEDYFRLRDRVDAAGCDVPILPGIMPVTQISTIERSEQLSGAPFPPEV
RARFDAVADDPEAVRRLGIEHAAQVCGELLDQGAPGIHFITFNKSTATREVYSLLDGAGY
GARGSVPPMTA
>A0A5J6UH05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. WMMB 499|TrEMBL
MRPVRPDRPPTVRELLATGGRSFSFEFFPPKTEKGARTLWRTIRELEPLQPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFCAVNHSQAELRHLIGRLAAAGVRNMLALRGDPP
GDPMGEWISHPDGVEYAADLVRLIRATGDFSVGVAAFPYKHPRSPDIESDTRYFIEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDVPIIPGIMPVTQLSTIERSEQLSGAPFPPEV
KARFDAVADDPEAVRRLGIEHAAELCRDLLDQGAPGIHFITFNKSTATREVYGLLEADGY
CGTSAPAAEPVASGSVPPMTA
>A0A536L8F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSPAPERQKPRLHPFLERLRRGPLLGDGAMGTQLHARGVSFERSFDELNLTEPKIVEEIH
RAYISAGAELIETNTFGANRIKLARHGLEGRVRDINFRAVKLAREAREITGEPVFLAGSV
GPIGQQLEPIGRITIAQATAAFEEQIAALLEGGADLLVLETFTNLPELLAAVSAAKKTTD
LPIVAQMTFAEDGLTLSAEEPSQVVQALERAGVDVIGVNCGVGPQVALEVLEAMRHETRL
PLSGQPNAGLPARVEGRFFYFATPEYFATYARQAADLGVAYIGGCCGTTPAHIAAMRAAL
QPVAGAPRIRQAPASTAIAIDLNPAEQLPATPFAQRLAQGSFVVSVEIDPPRGLNPSKCI
AGAQLINDAGADAINIGDSPMARVRMSALSLAIMIRQQVGIDTLIHFTSRDKNLMALQAE
LIGAHALGIRNIIALTGDPPRIGDYPSATGVWDVDSIGLIKILKRLNEGYDWLGTSIGKP
ANFTIACAVNPSAEDVDHEIDRFRQKIEAGADVAMSQPLYDLETLARFFEKTGPLPIPFL
LGVLPLQSSRHAEFMHNEVPGIVVPQALRDRMRDAGENGIAEGLEQSRELLTETRHLVQG
VYLMPSFGRYEVVAELVRWLRQQQSAPALPFPPSGGGNR
>A0A6B1A9D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARITRLLDAGQTLSFEFSAPRDEAGAERLKQTLDRLSKHRPQFMSVTYGAGGTTRGPTR
DWVRTIRDHFQVEAMPHLTCVAHTRDEIAAIIEDYQEDGVDNILALRGDLPQGVESPSQA
FDTAAELTDFIRSRADWDIGVAAHPEGHPMAASVEADLSHQARKLAQADFAITQFGYRAE
HYDQFVNQLDARGIDTPVIPGIMPPTNVAGIERMSAINTTEFPVEIRERLEAASSAAERR
EIGVEVAVRLGRELLDFGAPGLHIYTMNFARAASEVATALGWPAD
>A0A522NJV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
AQLAREARDVAGREALVAGSVGPLAAAVHGPARPPEAAVAAAFREQVEGLLEGGVDLFVL
ETFNDLAELLVAVATVRRLSDLPVVAEMTFGEELAAIDGTSPQTAASALAAAGVDGVGVN
CGVGPIVCLEALANMGRPSSTVARSIMPNAGLPQRIEGQFVYAAGPAYFGDVVERCLAAG
ARIVGGCCGTTPAHTAAMRAALDRALARAAGGTGAATAGSGVAEAPRSAIVDIGASAGGA
EPPPPSGLAKNLAAGRFVISVEIDPPHSVRIERTVEAARLLQESGVDLVNVSDSAMARVR
MGALAVAFAIQHDLDLECLVHITTRDRNLMALESELLGAHALGVRDVLALTGDPPRVGDY
PTGTGIWDVDSTGLIGILKRLNRGEDQAGRPIGAAAGFTVACAVDPTAVDLDREIERLQG
KLEAGADVVMTQPIYALGQWTAFLDRLEERTGRRDVGRPVLIGVLPLHTARHAEFLHNEV
PGITVPADIRAAMHAAGERGAEVGLEMALRLLDEIRPQVQGTYIMPSFGRYELAAELVRR
LRAAVPTAP
>A0A6B3CDL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID6648|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFV
>A0A7V3T703|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MRFIRDIYAAAGGRPVVSFEFFTPKTEEGERTLLQRTIPELLAFKPGYCSVTYGAGGSTR
DKTLAIVDRIQREHGLTAMAHLTCVAHTREQVVSILAQAKALGICNILALRGDPPAGTTE
FKPVPGGLQYAWQLVRLIREVGGFCIGAAGFPEGHMECKEGKYVDWERLKFKIDQGVDFV
ITQLFFDNADYLHFRDYLTQKLRVTVPLVPGILPVLSAAQIQKFTTLCGARVPPAMRARL
EALAADDKAVTEYGIEYATAQCQQLLREGVPGIHFYTLNKAYSTSRILRALGLG
>A0A2E4PWN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQPSGSASQHLSAMLENXDRFLTTVEIETSRGILMGEDSRKTMDSAQSLAEFDRVDFVSL
TDNPGGNPHIRPEVLGQELLSRGREVMINLSCKDYNXNSVESRLWALDSQGFSNVLALSG
DYPVGGFEGQAQPVFDIDSVGLIEMMAQMNEGLRNKXXGSSSXGXRLEETNFFTGCVVSP
FKKLEGELMTQYFKLALKXRTGAKFAVTQIGYDSRKXSEIHXYVESNGINVPLIGSVFIL
TAPAGRFFXXWGVPGVXVSDXLRDIANRQAKSKXRGRLFFSELAAKQIAILXGIGYRGVY
ISGRPSLDRVQXIXELXDSYSXXDWREFAAEINFSQPGEXYYYEADENPGLSSXNINRDY
XSSXSKXARAKSRIGVPLQXRIGKFVHDRVFSEGSSGFKLGRSIYKQIEKSKKLSDVAHV
AEQVSKVPLYSCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTKAGQCEILDKECIWIR
AYDRMKPYGDEVRMLQGPVIFKDGALQNTSAWGNTFLGRDHHAKKSDAVDEP
>A0A7J9ALR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium laxum|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVTHNPSFCDITWGAGGSTAD
LTLDIANKMQNIISVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNPPKSYITRTIGWDQFPHGRWGDSRNPS
YGALTDHQVHKVFEPSPFSFVWSYY
>A0A6L7WIP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTRPRHPFLDALDRGVVLADGATGTELLSRGWTGLPAAAVLDARDLVRELHEDYIEAGAD
LILTDSFAANPIHLENAGLADRTRDVNFNAARVARDAREIRGVDVLVGGSVGAIGRRFAV
GTVAPEQAYDAFAEQIGALVEGGVDLLVFETFLSLAEARIALSAARAITDMPVVVGLNFV
SALTTSAGEAFPEVLAELTAGGADVVGVNCGVGPRAALDVLEQVAAADPSARLFVAPNAG
LPRITGGRPFYPSSPEYFVDFALRAKDLGAAIVGGCCGTTPAHTRAMRAALDSAERMPAT
VEVLSRGPALAVSDTRGGFDVTAAPLAEEPPEPDEPSRLRDKLAAGQYAVSVEIDPPRGH
NPRKAVEGARLLRDAGADAINIGDSPMARVRMSALALALRIEREVGIETIIHQTTRDRNL
MALQSDLLGAHSLGIRNVIALTGDPLPEASESSAVWDVDSIGFVRILKRLNEGVDFAGNS
LGRPTDFFVACAANPTADDIDIELRRVRAKLDEGGDMLMTQPVYDLATLSEFFERLGPVD
VPVLLGILPLMSSRHTEFIHNELAGVVVPDAVRARMREAGDAGAAAGLEIAYEQIEETRD
FEWVSGIYIMPSFGRYEVAAELIERVRATAPVTTR
>A0A2D6AF39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSYTQSLFLNTLSGGTILADGGIGSRIFQMTGRLPSSEFVYETLNLRNSELIKGIHSSSL
TAGATVLTSNTFAANSTELTTASLSDQIHEINSTAVQIAREAISEYQIEFSAQETAFFVL
GSIGPGGNSIESYAEQIETLIGSDVDALLLETFVDIDFAMQITKAISSRPYAPPIIVHGA
LDPCIGDSRQWPIEPFEFATLAANAGASVAGINCVAPWVASEFVDNAKEAPAVVHGDLLL
SAMPNAGGFERIGHRFLARSNPKFMGKIARELGDSGTSLVGGCCEVHTEHVREMSAYLKS
RSSSAGIKTSKSLRSDAVSRTTRDKFRKVNGEFTRKLLEGEFAISVEMVAPKGTDLKALE
LRATIIQDFVDEGLADAVDITDGSRGLPLIPPGDLVELIRRRLEWQDEDKIEFIAHFAGR
DLNTLAVQSRLMGYHLRGIRNVLFITGDPPKMSPTYPRSSAVFDMNSIQMIRATISQLNQ
GRDFGDNPLGGERGSNTQFTVGTGFEPEAANMSLEFERLQAKIDAGADYVMTQPIFDNSG
LLNTLKPYKDSISVLPGVMVLNSAAHAERIAQVPGVNLPSNILDKMKRFSDLPDQRKVGL
DLAVSQAMAYKSEGWAGIYLMSPASLGAAKTVLKTLAD
>A0A535BTU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
RTGEKTLELVTRIKRHYHIEAMAHLTCANTADRTRQILNWMEREGVANVLALRGDPPTTG
EPFTPADPQLTHASDLIRLVRGSGYRFGIGAACSTEKHPESPDVEHEFQYLQLKVESGAD
FLITQLFFDNRFYFDLVARARAAGIKVPIVPGLMPVPSRRSLALMTTMSGASVPAALQGA
IDEASDDDAIRALGVRHCIAQCAELLEAGVPGLHFYTFNRARAPIAILAALRGQQLIAS
>A0A535QAJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MATFLRTPRYEIFPTDDVLEVVVRYVPREVSITVTASPRRGMPATVLLAVALARSGYTAV
PHLSARMIRDRGELGQILEALRGAGITNVFVIAGDAKQPAGEFPDALALLSALPEDHGLT
EIGVTGYPESHPFIHDDMTIQAMWDKRRFATYIVSNMSFDADTVKRWVERVRRRGVELPI
YIGMAGVADPARLLRLSTKIGVAEAARFLRGHPSWLARMFRPGGYEPGRFVGALLPDIAQ
HARRIAGLHVFTFNEIEPTERWRREMLSRLSQGEGA
>A0A3B9Z3T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIHDILHTTHPVFSFEFFPPKTEEQQRQLLETIRRLGPLSPAYVSVTYGAGGSTRALTI
DTVNRIKEEFGIEAMAHLTCVGASRDDIRETLDTLASHGVENVMALRGDPPKGTKDFEPA
PDGFAHASDLIQFINENYDFSIGGACYPEGHFEGNTGRRQDPDMDLEHLFKKVKAGAKFL
VTQLFYENEAYFQFVERARMFGIEVPIIPGLMPVVNAESIPRIAKMSGASFPDSLMREVQ
ARASDPDAVVELAVAFTALQADELLRHGAPGIHFYTLNRSPATSAIVSALRLIRPWEVHN
YA
>A0A5E7YEJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea sp. EC-HK425|TrEMBL
MTSSFRSSAEALSERIKVSFEFFPPKNGDMESQLWESISRLAPFQPDFVSVTYGAGGSTK
QPTLNTITRICDETELAAAAHLTCVGSDKATVDAVAREFQAVGVNHFVALRGDPPEGVGA
AYEPHPEGYANGAELVAGLRAIADFEISVSAYPERHPESPDFATDIDMLKRKVDAGATRA
ITQFFFDNDIYERYVERVRRAGIYIPIVPGILPIHNFGQVARFSKLCGASVPDWLARRFD
GLEKDPETRALVAAAIAAEQVNDLVERGIDDFHFYTMNRAQLVYAICHMLGLRGDDAGSV
GAAA
>A0A3D2LCS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp|TrEMBL
VAADLCRKLSDEGVSDFHFYTLNRAGLALSTCRLLGLKPKPVEAA
>A0A535ZGF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MACWPSAAPCSTTTARAWPACTASWRATSPSTALIPGAGGCRPTATPSSSCPTRGRDSVA
HSATVAYSATAHVVRPVGTRGVGRGLAAFLRAPRYEIFPTDDILAVVAQYVPKEVTITVT
ASPRRGLPATVHLAVNLARLGYRAIPHLSARLIRDRVELGQILEAVRAAGIHGIFVVAGD
ARESAGEFPDALSLLAALPPDHGLTEIGVTGYPERHPFIHDDVTIQAMWDKRRYATYIVS
NMSFDPDTVKGWVERVRRRGVELPIYVGMAGVADPARLLRLSTKIGVAESARFLRGHPSW
LARMFRPGGYEPGRFVSALLPDIAQPDRRIAGLHVFTFNEIEPTERWRREMLLRLTQGEG
A
>A0A536E5N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKHQKAGRGMPGPSRLAELLRDGRFVVTAELTSTNSADPEATWRLAEVLRGSVDAVNCTD
NTGAHVHMSSLAAAHLLVEKGIEPIMQLTVRDRNRLALQADLLGAAALGVRNIVLMSGDD
VTVGDHPEARRIYDIDSMQLIEVAAGMRDRGTYLSGRTLDQAPSFFIGAVENPFAPPLEF
RPLRLQKKVRAGADFIQTQLVFDVPLFARFMSMVGDLGLTDKVFIIPSIGIPRSARGARF
MREKVPGLHVPDSLVDRLEKTPPARQSQEGIQIAVELLNAVRQIPGVAGVHLIGIKWEEG
VVQVAEAAGLLPRPTLSPLATVGGSR
>A0A2E8X3B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNPELISNLAQRLQNGLFTVTAEVTLPDSXEKNAXVERAQMLEPYSDAINITDSTGAVPH
FSNIAAASILIENDIEPIIQFSCRDRNRIAVQADVIGAHAMGVRNIFCVTGDGVQTGDHP
EAKPVFDLDSVTLLTTMNHLKTRGKFLSGRELDAKPNLYLGAAVNPFVPPFEERALRLLK
KHKAGASFFQTQYCFDIERFKSFLDRLLGLTKGTPPPLLVGVGPLRSARFARWLRENVPG
VAVPDHVIEKIDKYPRKEQQKAGVEACIQIVDAVKTLTGVAGIHVMAYNWEASVSEIVEA
TGLSKSERND
>A0A536RWA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLARSKPSVSFEFMAPRDESEVETLERTIAALAGHAPDWVSVTYRVRTGEKTLEL
VTRIKRHYHIEAMAHLTCANTADRTRQILNWMEREGVANVLALRGDAPTAGEPFIPADPQ
LAHGSDLIALVRRSGYRFGIGAACSTEKHPESPDVEHEFRYMRLKVESGADFLITQLFFD
NKHYFDLVARAREAGIKVPIVPGLMPVPSRRSLAVMTAMSGATVPAGLQAAIDAAPDDDA
IRAVGVRHCISQCAELLEARVPGLHFYTFNRARAPMEILAALRGQQLLAS
>A0A517X3V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia aquarii|TrEMBL
MTRISELYQSGTFDLSVEIFPPKSEKGDANLFKTLEELIGYQPAFVSCTYGAGGSTSKRT
IELCKIIQDRFQTPATAHFTCVVSTREELIEWLKNASEAGINNIMALRGDPPEGQETFIP
ADGGLRYANELVALIREHFPKMGIGVAGYPEVHPDAVDAKTDLANLKRKVDAGADAVYTQ
LFFNNSCFHDFRERCVQAGIHCPIIPGIMPITEFKRIQRITAMCNSTLPVELKGKLESVK
DDATAQFEIGVEYAIKQCQELIDDGVPGIHFYALNRSPACKRIFEALGFHKR
>A0A5N0VLN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis acidicola|TrEMBL
MPFRGTENAVLDHVPAEVPLTVTVTEAKGLEATLDLSSALRAHGYQVSPHIAARMVKNET
HAEDIATQLADAGIDRVFVIGGDAPVPVGEFTEALDVLRVFADTGTFQRTGIGGYPEGHA
KIGNRELDTALAAKAPLATHVITQICFDAKTTLDWARRVYRDHPELEVTIGVPAPVSRQK
LMRIAGGIGLGQSARFLRKQQNVIRKLIRPGGYRPDKLLRAFEPRLGEPDLNITGIHLFT
FNELHGAEAWRQALLARLDAG
>A0A3D5E491|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRNFVLRIHNIVACTRTISFEFFPPKDKSGMIGVLEKIKSLKSYSPDFISITYGAGGYTR
RFSEELIMQVKAEHDLEVMAHLTCIGHSVDELDAILRRWDKSGIDNIIALRGDLPKDGFR
NSNINSTFQYASDLIKFIDENYSFCIGAACYPECHPESISIEDDLSFAKLKVENGAEFLI
TQLFYDNDDFYRFVERARSQGITVPIIPGVLPVLSAKQTRRFTSLCGARIPSNLAAKLNK
YENDDKSARAMGVDYAIKQVESLWDYGVCGVHFYVLNRSYSVSKILDSLKLDRQLI
>A0A536QSY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARITDLLAAGRTVSFEFFPPKDNEEQRLLTRTIADLQPLRPSFVSVTYRGGRISRERTT
RVVVDLLRTTDLTPMPHLTCVAHPRFELGEIIGGFRAAGLENLLALGGDPLPEEESYKEL
AYASELVELGRRLGFESIGVAAHPAGHPRSPDLVSDRRYLAVKMRLADFAITQFFFKVEE
YKRLRDEMAALGITKPIIAGIMPITSLASVQRMAELSGYAVPDDIVKRVEAGGEDRDEIR
KRGIAVATELCRDLLDAGVPGLHFYTLNFSKATREIYTNLGLAV
>A0A2E3V0M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLNTIEIVPKQLEKIFSLPKNMFGDVYVAFIPGDPVENIISCCEKLVNKGFSVIPHLPAR
NIKDENELENFLFQLNKLNVKKILAIGGSSSEKKPTFSSTYEIFETGIFENFDFDQINIA
GHPEGNPFDEKPDENLKKKLDWIVKKNYNCNIVTQWTFDTEQTNIWLEKINKDISNISNN
TEIHIGIAGPAKFTTLLKYAKVCGVSASSIVAKNKGLGLTKLLRHNPKDIIESLVGYDNL
HFFPFGGINELIEWKKR
>A0A535KET7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGFGDLPPAHGREDARARHAHQAPIPHRGDGPSHVRQYGGSHAPGPQLDGALADPQLTHA
SDLISLVRRSGYRFGLGAACSTEKHPESPDLEHEFRYMQLKVESGADFLITQLFFDNRFY
FDLVARARAAGIKVPIVPGLMPVPSRRSLAVMTTMSGATVPAALQAEIDGAADDDAIRSL
GVRHCIAQCAELLE
>A0A508WUI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium medicae|TrEMBL
MNGRLPNAVDCRGIRFSFEYFPPKNDEMEAQLFQTVTALSVFAPAFVTVTYGAGGSTKAR
SLTTVKRMIGEMAIGNTAAHLTCVGAPKADVDAVVDEFVACGVRHFVALRGDPQGGIGSV
YEPFPGGYENAADLVKALRARGDFEISVSAYPEKHPESSDVAADIDMLKRKVDNGATRAL
TQFFFDNDDFERYLERVRRAGIGIPVVPGILPINNLAQVQKFAGLCGARVPESLISRLGP
LNDRPEERFREAAHIAAEQIADLVRRGVNDFHLYTMNRPQLVTAVCGLIGYEAERASAQP
VDTERSFRAAATG
>A0A3C1JQF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
YFQFVERARMFGIEVPIIPGLMPVVNAESIPRIARMSGASFPDSLMREVQARASDPDAVV
ELAVAFTALQADELLRHGXSISTP
>A0A1A0HD02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993|TrEMBL
MKITEKLTQAHSGANPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFVDITWNAGG
RSSSLTNEMVYTAQSTLGLETCMHLTCTNMAVSYIDEALEKAFKAGCQNILALRGDPPLD
GSESTGDFRYAKDLIAYIRKNYGDHFNIGIAAYPEGHPEENDNGKLLQYLKEKTDAGADF
IITQMFYDVDNFIGWCRKIRDYGINIPIIPGIMPISTYSAFIRRANWSQVAVPQHFLDAL
DPIKEDDFAVRELGSQLVADLCQKLIDSGFVNHLHFYTMNLEKSTIMLLEKLNLVECVKE
IDAVGEDLPWRKSLHPNRSKEAIRPIFWQNRKYSYISRTSGWDEFPNGRWGDSRSPAFGD
IDLSASELLRQSPKRALELWGCPQELKDLANIVIRYLNNEVKALPWSDGPIGTDTNVLKE
SLIKLNENGFITLNSQTALNSVRSNDKVHGWGPKNGFVYQKQYLEFMVHKDVASRLVTAV
ETHNQADPTGLISFYMVDKEGNLTTNAHDDDINAVTWGVFPGEEILQPTIVEKVSFLAWK
DEVFSLIKEWDTIFHSKVIGELVEAEKIDAFSRFLTGFGNNYVLCNMVNNDFTSDNSHMF
QLLHGLTEAAN
>A0A099LG33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassotalea sp. ND16A|TrEMBL
MNARARQLDLLNRTIRDIDNDLNVSFEFFPPNSPEMENTLWNSIERLAPLNPSFVSVTYG
AGSGTRDRTHGVIKRIQKDTGLIAAPHLTCIDAGREELIDIAKDYWESGVRHIVALRGDL
PNNSSKPDMYANDLVELLKGVADFDISVAAYPETHPEAPNAQFDLVNLKRKVDAGANRAI
SQFFFDMDSYLRFRDRCVAVGINVEIVPGILPVSNFATLKRFADMTNVHVPDWMGKMYEG
LDDDPTTRNMVGANIAMEQVKILRSEGINDFHFYTLNRSELTYAICHTLGVRP
>A0A2E6ZML4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTPKPVSDLARRLEHGLFTVTAEVTLPDSIEKKALVERAQMLEPYCDAINITDSTGAVPH
FSNIAAASILIENDIEPIIQFSCRDRNRIAVQADVIGAYAIGVRNIFCVTGDGVQTGDHP
EAKPVFDLDSVTLLTTINHLKTRGKFLSGRELDDKPNLYLGAAVNPFVPPFEERALRLLK
KHKAGASFFQTQYCFDIERFKSFLDRLLGLTKGAPPPLLVGVGPLRSARFARWLRENVPG
IDVPEHVIEKIEKYPRKEQQKAGVEACIEIVDAVKTLTGVAGIHVMAYNWEASVSEIVKA
TGLSKPERDN
>A0A536J2J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVRPLGAQSVGQALAGLLRTPRYEIFPTDGVVELVAAHVPKEVTLTVTASPRRGLPATVV
LAARLSRLGYRAVPHLSARLIRDRVELGQILDALKAAGIRNVFVVAGDAREPAGQFPDSM
SLLAALPPDHGLTEIGVTGYPESHPFIHDDVTIQAMWDKRRLATYIVSNLSFDPATIKRW
VERVRRRGVQLPIYIGMAGVADPARLLRLSTRIGMAESARFLRGHPSWLARMFRPGGYAP
GRFVSALLPDLAQPDRRVAGLHVFTFNEIEPTERWRQEMLARYAQEVV
>A0A504BSU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-1-3A|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILNETSLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A1G5GS56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira sp. Nl5|TrEMBL
MESQKKFAPTFSFEFFPPQTQEGTEKLRATRRQLAQLNPKFFSVTFGAGGSTRDRTLETV
LEIQAEGYAAAPHLSCIGSTSENIRTMLQKYRDGGIRHIVALRGDLPSGMAQGGEFRYAD
ELVKFIRKEFDDAFHIEVASYPEYHPQANSAQDDLRNFKRKVEAGADSVITQYFYNADAY
FRFIEECEAMGIGIPIVPGIMPINKFSQLARFSDACGAEIPRWIRKKLEGYGDDSASVRA
FGLDVVTDLCDRLLQAGAPGLHFYTLNSAGLTTTIWQRLGL
>A0A2D9GP15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLSITELIRSSSQTVYVLDVSPPRSGNDLLFQELLDLTPDVFSVAYNPGLSVRVNSVMLA
SWXQNSTGIPTSFFLATRDMNKLALQSLLLGAQLHGLNNVTVVQGDAFSETKLQXVKGVN
DFTPTEFIXAIKNMXXRKDFENKNLIXPTDFCLGATVDXSKDLENEAELLHKKIXXGSDY
IVFQPFFDFDLPEKLFXIFYKKFHXHVDXPIIWGIQMLENFSKSFSEIPNWVLDELLKGR
PSIEIAQEMIEDLKNTQKVGSVYLVPPIFENGRRNYEVANELLTLIR
>A0A535YT57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRVDSVLTGRRPIFSFEFFPPRSDDGVRQLFETIAQLRELEPTFVSVTYGAGGSVRTRTV
ELVTRIRHELDIEPVAHLTCAGATVAELHGIVDTLRESGIDNILALRGDPPDGAASFPVV
EGSLAHGNELMQLIRDRADVCVGGACYPEKHLESPSFDDELRYTRLKVEAGASYLITQLF
FDNRAYFDFVAKARASGVTVPIIPGIMPVTNVDQIRRFTSKIGATIPDALLEALHTRAED
HDAVLQLGVAWSTLQCAELLAGGAPGVHFYTLNRSPATRAILSALRAARPWERVR
>A0A497AFV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MATPFRKILKTKDFVVTAEAAPVKGSNVSKAIEHIELLKDKVDGLNVTDNQSSVMRYPSL
GVCLLVKEHGGEPVLQVTCRDRNRLAIQADLLFAYSRGVDNVLCLTGDSIDVGDHKEAKQ
VFDLDSVQLIHLIHTLNSGQDMAGNELDGNIDFCIGTTATPSADPLEPQLIKVEKKLAAG
VEFIQTQAVYELDELKRFVEFVRKIDDKVKILGGIVPVIGAKMAAYMNDNVPGVFIPQHL
IDELAQTPKGTGVAKGIEIAARMIRQMREEKICDGVHIMFIGREEKVPDILEAAGLL
>A0A3D3DFT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
PRQCEGLLQADVPGIHFYTLNKAAATVRILQNLGRAR
>A0A0B7IQU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga canis|TrEMBL
MFVVLPREYNFLLKTKMKVTEHIARSKGKTLFSFEIVPPKKGNSIEELYRNIEPLIEFKP
PFIDVTTSREEFFYKQHPNGLLEKKITRMRPGTVGICSAIQYKYGVDTVPHVLCGGFTKE
ETEYLLVDCFYLGIDNVMALRGDARKEERYFEPTKDGHTYAVDLVRQIKDLGRGKFLHDV
IETDYGTDFCVGVAGYPEKHIESPSMTFDLARLKEKVDAGADYIVTQMFFDNQKYFEFVE
KVRLMGIDIPIIPGIKPITTKKHLNLLPQVFKLDLPEILVSELEKCKTNEDVKQVGIEWA
IEQSKELKLWGVPTLHYYSMGKSDNIVDIVSKVF
>A0A2E6PP52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIKDILEKTRPVSFEFFPPRQADGIPAVLETLDELKVYSPDFVSVTYGAGGSTRAFTEE
ITFEAKRTAGVEVMAHLTCVGQTKEEIHGVLERLEAEGVENIIALRGDPPRGSTEFVPVE
GGFQHATDLLEHVXSNFKFGVAAACYPEGHTESVDLGSDLKYVKMKVENGADFLVTQLFY
DNRHYYDFVERARAGGIDVPIIPGVLPVLNSAQVRRFTALXGSEIPPELDKLLDKYADND
DSARDMGVEYATAQVRDLWDVGVPGVHFYVLNRSYSVSRILDNLTIPGHHRQD
>E6W0X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurispirillum indicum (strain ATCC BAA-1389 / DSM 22839 / S5)|TrEMBL
MTTLPTRIAVELVPRSDESLQEELAVLEQFPVVTAVNIPDILRFDMRSWQGCRLVRGHGL
DAIAHIRAIDIHPRKPLPMVEYLVEHRIEEVLVIAGDIPQNHARTIYPSTSVDIIRKFKR
EAPHIRVYAAIDPYRQSFREEMEDVQHKLDVGADGFFTQPFFDMRLMELYGELLEGEQVY
WGVSPVLAERSQHYWETRNAAVFPRSFEPTMNWNLEFARQALDFVHATDGFHIYFMPIKT
NLNSYLQGIFPR
>A0A174ER61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRSHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A3D5CNM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIQDILTKTRTISFEFFPPREATGINAVLNKIESLQSYSPNFISVTYGAGGSTRKFSEE
LTTKAK
>A0A535ICZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKARLKAAPRSRPRSAVRHEHAPRRHAALHSVSIRWRCHHAMTKAAAIGGSPVAIGSRLR
RALDAGRSVITAELAVPATVAHELILERAKGLLRPQIVAMNITDGLRGRPALSPIAAAAI
LTHADLGVEPIVQVVARSRARNALIADLLGASALGVRNLLCMTGDVPESSADIQDVDVFA
LIGLARGFPAGLGTELLGTAEPFCVGVAWSPFARDPDHEADRLARKHSAGALFVQTQPVF
DAHAFAAAIDRLPRTLADLPIIVGLAPIRSCDHARRLGAIPGIVVPDRLLALLDRASDEA
DACERYWAYLDAELDWLTRNVPHRGFHLMPIGHSKRGIRQSSSFDRLYAAVTRALDAAPP
KPADVAAPVDVSVFGTSAG
>A0A3N5LW46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGQPTSFFVGCALNLIPANPEDEIKNLGRKLRAGADFILTQPVYEAGPALAFLDRARNEL
GSLDVPVIVGVLPLVNPRHAAFLHHEVPGIDIPEKTLKRMEDSGENAARTGREIAIELIQ
QLRGSINGVYLMPAFSRYDLIAEVIDNIATHEPVS
>A0A093ZWZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4281|TrEMBL
MADSPTTDKITDKIAALPHDASYFSLEFFPPKTAMGSTNLRARLDRMSRALRPLFVTVTW
GAGGSTATRSMELAELCQRELGLTTCLHLTCTNMSRALVDDALRAAKEAGIQNILALRGD
EPRGEYKDALEEGKEGEDEFVWAIDLVRYIRKNYGDYFCVGVAAYPEGHADGSHPTEQSL
EHDLPYLVEKVQAGADFIMTQLFYDVDAYDTFEKVLRDHSSGAFKTIPIIPGLMPIQSYQ
ILRRTTKLSNAKLPQSIIDRLDAVRSDDEMVKKVGVEILAEIVESVKHTKQRTKGPKGFH
FYTLNLEKAVAFILERTNLIPSFTPVLTSDAFAVDDDITDTIPLPALLINGERKSRRQSS
VGSGPHNFVIIDREEASGFETTGAEAGIPKDGVDTRANTLAISEGEGALGREATWDDFPN
GRWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRADITSIFVQYLNGTLSALPWSD
EPITAETNLIKDELVKLNQKGWWTIASQPAVNGTRSQDEVVGWGPKGGWVFQKAFVELFV
PSSDWPRLKGLLEGNAEVSFLAQSASGEYLKSKMDAGPGDEETETNAVTWGVFPGKEIVS
PTIVEEVSFRAWADEAWQMWVEWAAVFGKSGEQSRRFLDGVAKDGWLVNVIWHDFVGMCK
AKEGTSEEEGYKGLWDMLIEA
>A0A7S1T4Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Compsopogon caeruleus|TrEMBL
MAQVEPLFCDMTWGAGGTTSDLTLDLSGNIQRYLGLDVMMHLTCTNMPQGAVQVALESAK
ARGIRNILALRGDPPAGQEWKACEDGFAHAEDLVRYIRKHYGDFFSICVACYPEGHPAGF
LDGKLTFAEEMAHLKAKVDAGADFLITQMFYDVEEFLEFVGKCREIGITVPILPGILPIQ
NYAGFKRMTGFCRTKIPPEVAEALDPIKDDDAAVRRFGINLGVDMCRKIIRSGLVPGIHF
YSLNLEKSVMAIIEELGLVSRTESIRSLPWRPATWDKRRLETVRPIFWANRPRSYLDRTA
EWDEFPNGRWGDSRSPAFGDLSDYHLMGGAGFLSPELKARYMEQLGTISSVEDVTRIFVD
FCKGEISRLPWVEGENFAPETKAILGPILWLNQHGLLTINSQPRVNGAPSGDITVGWGGP
GGYVYQKAYIEFFCDRAMMERLLEESKKFGSLTILAVRCESSEILSNVKKPRTNAVTWGV
FPNQEVIQPTVVDPVSLLAWKQEAFDLWMSAWGNLYPEDSKSREVLKEIQHSYFLVTVVD
DDFVAGDIFKIFSAVIKSQ
>A0A7V1K4R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfofervidus auxilii|TrEMBL
MRVKDILNATKISFSFEFFPPKTDTGWKQLFDTISELMLLKPSYVNVTYGAGGSTRDRTY
NLVTQIQRETGLTVVSHLSCIGSTKEEIRSILEKYNQSGVENILALRGDPPKGEKLSSLK
GDFKYAADLVAFIKKHFPHMSIGVGGYPEGHPETPNRLKEIEYLKAKVDAGADYIVTQLF
FDNRDFYDFCERCELVGIHVPIIAGILPITSYQGMIRMAELAAGSRLPAPLLKSVMRAES
DEYVEKIGIHWATEQVRDLVDHNVRGIHFYTLNNSRPIF
>A0A3R6TCP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. OM04-15AA|TrEMBL
MNIKEYIKEQRLITDGAMGTYYEEKYSEDTVIAEKENLKNPEQIKEIHLEYLRAGARLIR
TNTFAANTMFLADMQEVKETVRAGYEIAKEAVTAFQAENGKEIPVFIGADLGPIYDLDHQ
DYDNVLQEYKEICDTFLSCGADCFVFETQSDFTYIEPVTAYIKEKSDAFILVQFAFDKSG
YTRSGLSMQRVAVEASEMENVDAYGFNCELDSTHMYQFMKNLKFSSDKFVSALPNAGYPY
TLRGKTIYSNNASYYAEKMKDIAALGTDILGGCCGTTPEYIALLSGELQDVPKAAKKIEN
VVTQEVTRTPSIFEEKLSRGEKAYIVELDPPFSEDASKVMKGAEDLRKCNVDLITLSDSP
MARARMDAGQLAVKIQQKTGVAVMPHISCRDRNVIALRAGLLGMHMNDVRHFLIVTGDPV
SRADRERVTSVFDFNSIKLMQYVKEMNLEVFAQEPVYYGGALNYHGANPDAIIERMKRKA
EAGCGYFLTQPVYTEEDVERLTYIKEHIDTKIMCGIMPLVSYKNAMFVKNEMPGIHVSDE
IVNRYREDMTREEAEEVAIELSVEIAAKLYDIADGFYFMTPFNRTGLIARIIEAIRQEEE
RR
>A0A848K691|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthobacter sp. SG618|TrEMBL
MTTPASIPAAAPVRASREMDRPPVNVSFEFFPPKTEEMEKTLWSSIHRLAPLSPSFVSVT
YGAGGSTRERTHATVARIVKETDLHPAAHLTCVGASRAEIDDVVRAYKDAGVKHIVALRG
DPATGVGTAYEPHPEGYPYACDLVEGIRRIGDFEVSVSAYPEKHPESANLDADIDYLKAK
VDAGATRAITQFFFENDVYFRYLDKVRAKGIDIPIVPGLLPVTNFKQASNFATRTGASVP
AWLLKRFEGLDDDVETRKLIAAAVAAEQVTDLVDRGVTDIHFYTLNRADLVYAICHLLGL
RPNAGPVPQAMAV
>A0A1R1EUP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus rhizosphaerae|TrEMBL
MKPDLRQAWDQQVLIGDGAMGTFLYQMGFPVGISYEELNLTSPEVIKDVHRRYVEAGAQI
IETNTFSANFDKLSKYGLESKVEDINRAGVRIAREVAGTAGYVVGAIGSIRGGKRTNVST
AELKKYFEQQIQALLQEGVDGILLETFYDVEELYLALSIVRKLSPLPVICQFAVEDVART
LDGYTMPEAFRMMQQQGADVIGFNCRTGPNGIMSAMKTLGGHLSVPMSVYPNAGVADYVD
GEYQYGAKPDYFGQMAVKFADLGSRIIGGCCGTTPAHIAAISSALQGYEPQPITYGPIDI
APAPIEIHEHLAPDGGGEGKGGSPNLVDLVKERHTVIVELDPPRDLDIAKFMKGAQVLKD
AGADALTLADNSLAVTRMSNMALGHLVQAQTGLRPLVHIACRDRNLIGTQSHLMGFDALG
IDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFVVGAA
FNPHGKHLDKAVLRLERKIAAGADYIMTQPVYDPELIRALKEATSHLDIPIFLGIMPLAS
GRNAEYLHNEVPGIQLSDDVRRRMSGLEGEEGRAMGVAIAKELLDVAMEHFNGIYLMTPF
MLYEMSAQLISHVWEKSGRRQSPLFHR
>A0A4U3FJE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. CFBP13512|TrEMBL
MKPDLRSKWTDSVIIGDGAMGTYLYQLGFPVGISYEELNLIRPHIIEDVHRQYVNAGAQM
IETNTFSANYDRLSKYGLEDKVDEINRAGVRIARAAAGDQAYVVGSVGAIRNGKRTNIPR
SELRQYFRQQVSSLLDEGVDGILLETFFEVEELAIALRQVRKLTDIPVMCQLTVEDAIRT
LDGFALPDAFALLTDAGADMVGLNCRVGPNGTLHALEAIQGKVSLPLSVYPDAGVADYVD
GEYRYGASPAYFGQRSVRFAELGARVIGGCCGTTPEHIAAIARALEGYTPETLDFSNVQK
PTPQISVTIENAIMDESDRNGEDVPPTLVDLVRERPTVIVELDPPRDLDITRFLKGAAAL
KEAGVDALTLADNSLAVTRMSNMALGHIVQREAGIRPLIHIACRDRNMIGSQSHMMGFDA
LGIDHVLAVTGDPSKFGDLPGASSVYDMTSFDMIKMIKQLNEGIAFSGKPLKQRAKFVVG
AAFNPNVKHLDKAVVRLEKKIAAGADYIMTQPVYDVQLIADIREATKHLDIPIFIGIMPL
ASGRNAEYLHNEVPGIQLSDEVRGRMAGLEGEEGRATGVVIAKELLDVAMEHFNGIYIMT
PFMFYDMSVQLTEYIWTKAKRRPNPLFHTR
>G5K349|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus ictaluri 707-05|TrEMBL
MAKLLERLQEGILIADGAMGTLLYRNGLDNCYEAYNFQKPEDIKTIHKAYIKAGADIIQT
NTYGAKRHKLKGYGLEDHFEEINIAGARIAREAAGSEIFVLGTIGASRGIRQCDLSLDEI
VSETVEQTKVLLSTQLLDGLLFETYYDTEEIFAVLEAIRPLTDLPIITNISLQEVGLTAR
GQSITEVFSHLVLLGADLIGLNCHQGPYHMIQSLKQVPLFAHSYLSVYPNASLLALDTGD
EFDYQFSSNAEYFGQSVVAMVNEGARLIGGCCGTTPDHIKAVKRAVRGLSPITKKQIKPI
VSSAEIIPEDQDGERLVDKVKRDITVIAELDPPKTLDISSFKKGIRALDATSLDAITLAD
NSLAKTRICNVSLAAMMKEEIDTPFLLHLTCRDHNLIGLQSRLLGMDILGINHILAITGD
PSKLGDFPGATSVYDVNSFKLIELIKDLNKGQSYSGTSLKKATHFTIGAAFNPNIKNLSR
SGRLIEKKIEAGADYFLTQPIFKAELIPELYQLTKSYEQPFFVGIMPITSYNNAVFLHNE
VRGIDLSEEFLQALEAVKDDKEQCQAIALAESKRLIDEALNYFNGIYLITPFMRYDLTVE
LINYVEKMKQKRISDSLISNAI
>A0A0W7WCH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter sp. G161|TrEMBL
MNATLLTGSAPTRARFSFEVFPARSGAAALALGNSVQHLSAAGPDFISVTYGANGSHRDA
SLDLLAYLRDHTDALPLAHLTTVGESREVIRETIHRILDAGIHDFLALRGDPPRGSDEAS
PLVAGSLSALELTELISEARAERPAFTSVGRTAVAAYPNGHPLSQGQSADIDWLLAKEAA
GAQFAITQLFFRAEEYLSFADAARTAGLRMPLLPGLMPVSTSGQLRKVASLAGRPAPVLL
ERSLEEAGGYAPELGVEHTISLARELLAGGAPSIHLYTFNRHEQVLAVLGELDLLG
>A0A1F6DHC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kaiserbacteria bacterium RIFCSPHIGHO2_02_FULL_49_16|TrEMBL
MKITDLVKQSSKPFISIEIIPPRKGVKLETMFAELEALMRHKPAFMSVTSHAHEWSIEKV
DGRDVERMKHKRLDTNAICIAAQARFGVEPTPHIICRGFTKDETEDVLLTLNFHGIENIL
ALRGDGPPTRGGSADAFANERAADLVEQIQLMNQGVYLDPIENADKTDFCIGVAGYPEKH
FEAPDMKTDLANLHRKVHAGAHFIITQMFFDNEAFYRFRDEASKIGINVPIIPGIKPLYK
REHLDVLPKIFHIKIPQTVRDSIERFSNPDDVYKASIEASVAQCKDLLAHGVPGIHFYSM
SVAKPTSDVLKGIKS
>V0WX92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 908525|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>I4M4B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis 00703Bmash|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIRSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>I1CGQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)|TrEMBL
MKIIDKIKQAQEKKTINYSFEYFPPKTELGYANLIDRIGRMSQLQPEFISCTWGAGGSTH
ERTLELCSTAQSVHGLDTLMHLTCTNMEKDKIDVALKEAKTNGIQNILALRGDPPRGAEY
WTPVDNQFTHAIDLVKYIRQTYGNHFSIGVAGYPEGHIDCPSQEQDLKYLKEKVDAGADF
IVTQFFYDVDAFKNWIKRCREIGIQVPIVPGIMPIPTYQTFRRMIHLCNVKVPTHLMNDL
DAIKGDDQKVKDYGVQLAVKMIKQLHKEANVCNFHISTLNLERSTRLILEQLELAHPQEH
AQVNKLSPWAPIHDPAKAELWDEFPNGRYGDYRSPAYGETTYGANQILPTSQAISKWGEP
KSEEDINELFRKYIQGELDSLPWCEENLQTETDSIRQQLLSLIKQGYLTVSSQPAVNGAA
SDDPVYGWGPKGGYVYQKAFIEFFISDKIVKDLITRFSKEDAITYYITNRKGDFLTNVSD
PDAQNAVTWGVFPGKEIIQPTIIEKASFESWKVKIQKYFYEIDTSSSLF
>A0A1G5E089|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoluna spongiiphila|TrEMBL
MRPKRTPRTASRLEQILAEGHLAVTSECGPPRGTDGNVLEKKGALLKGYVDVVNVTDNQT
SMTRLCSLAASIRLKQAGLEPVLQMVTRDKNRIALQSDILGAASFDINNILCLTGDHQSF
GDCKTGQNVHDLDSMQLLQVVRQMRDEGTFIGGDAISQPPAMFIGAAANPFADPFEIRVP
RLAKKIAAGAEFIQTQCIYNMDKFETWMKGVRDRGLHEQTYILAGVTPFKTAGMAKYMRS
RVPGIDVPEELVKRMSDTPKEKQADEGIAICLETIERLKEVEGVSGFHIMAIEWEEKVPE
IVERAGLYPRPELEEPAPTPAAAAAR
>A0A084JMT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacrimispora celerecrescens|TrEMBL
MKIKDILSQGKPTLSFEVFPPKTEDKYESVELAASEIAKLKPAFMSVTYGAGGGTSQYTV
DIASALHHQHHVTALAHLTCVSSTKEKVHQVLGELKEAGIENVLALRGDMPTNAPAKKEY
HYASELIREIKEAGDFCIGAACYPEGHVESANKIIDMDYLKQKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVVAGIMPVTNVKQIIRSCQLSGTYLPSRFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANGVNAIHVYSMNKLDVALKIKENLSEIL
>A0A161I8K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Isoptericola dokdonensis DS-3|TrEMBL
MVAEALPHPHRPTVSFELMPPRRPAAAPRFWETARRLVDARPDFVSVTYGAGGGDRDTAR
DVVATLLAGTSVLPVAHLTCVGASREDVSAVIDTFLEAGVRTVLALRGDPPKDQPDWRPP
ADGVHSSLELIALLREVEARRCESDPSTALRGAARPLTIAVATFVDGNVQAGTTRAQEVQ
RLLEKQQAGASFAITQLFYEATSYTDFVTAARAAGVTIPILAGLLPTTDPRRLRRVEELT
GVRAPQHLLDALDALPDAEAQHAYGTAYGTELAQRVLDAGAPGLHVYTFNQFRPALDLLE
GVNLGGTPSDGVDLARRPWVPSIPAV
>A0A0L0N1A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolypocladium ophioglossoides (strain CBS 100239)|TrEMBL
MHIADMLREAEKGGRPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLERVNDALSKAYKAGCTNILALRGDPPRDQEK
WTATDGGFQYARDLVKHIRSTYGNHFDIGVAGYPEGCDDNKNVDELLDHLKEKVDMGATF
IVTQMFYDADNFVRWVGKVRERGITIPILPGIMPIATYASFLRRANHMQCKVPEHWMDAL
EPVKNDDVAVREIGKTLVAEMCRTLLANGIFHLHFYTMNLAQATRMVLEELRWAPSAERP
LLPALPWKQSKGLGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFRELDA
YGIGLTGTNEANRKKWGEPTTVRDIANTFVRYLDQKIDSLPWSESPLTGEADAIRRDLIA
LNKRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPPSILTEIVSRIESQP
NLTYYAVTKDGDLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
AHCFDSNTPSRALIEKIMNEWYLVNVVNNDFHENHTIFELFKDIEVPDVDAPQAV
>T0TAG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteriovorax sp. DB6_IX|TrEMBL
MKVIEHIEKSSNPLFSFEIVPPPRGRTIQAVTDVVKTLLPYNPAWIDVTAHPAGAYYNEK
SDGSIERKIYKKRPGTIGICGVIQNRFKVDTVTHLLTQGFTKEETEDALIELNYLGIHNV
LALRGDGLNYNKKYDNKRQRNHYAIDLVEQISDVKKGIYMDEINESLPMDFCVGVAGYPE
KHFEAPNMKLDIQRLKEKVNAGADYVVTQMFFKNNKYFEFVDSCKDAGIDCPIVPGIKVI
KNLKQFRSVPSHFYVDFPDEFVEEAHENPDHVEEIGIRWAIKQGEELLNANVPSLHFYVM
NDAKSVSQVVKKLFK
>G7WEW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus orientis (strain ATCC 19365 / DSM 765 / NCIMB 8382 / VKM B-1628 / Singapore I)|TrEMBL
MENKFKESLLDKNTLSVTWELVPGRGANEKAQVTAIASAEQAAKGGRVHALTITDNPGGN
PAILADTLGMEIVKMGIEPLVHFTCKDKNRNQMESQLYALDRAKVRNLLVMTGDYTYSGF
KGRPKPVFDLDPSNVLQLITEMNKGLEVPGMKGPTYHAPSDFFAGAAVSPFKSTEAELMV
QYYKMKKKIQGGAQFIVTQLGYDARKCHEVLQFLKVNNLDIPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAQLNEEKTAPDKGVEQRMLRAAKMYAFMKGMGFAGVHIGGHNLKYEQ
VEFIIDKGEELYPNWQDYIKEFDYPQDNGFYYFEKDEKTGLNTDRPTNRANRPLDAPSGF
MNSMMRGMHSLMFTPNKKLFPVMRKMYHAAEGSKKAEKRLHALEHIAKVVMLDCKDCGDC
AILDLGYLCPMSQCPKNQRNGACGGSRDGWCEVFPNEKKCVWVRAYARLKKYNEEHTLDV
PPVPPANWELYQTSSWSNFYLGKDHSAPILGIKRPESKIKK
>A0A1C6DI09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKEWLKGLKEHRLLGDGAFGTYYSGLEGGSARIPEWDNLRRPDKVEQVHRAYMEAGARFL
RTNTFAANTRRLECGLREAGQAAAAGYRIARSAAAAYMREHTEETAEHGPILTAADIGPI
PMDIHQTAEHVIEEYRYICDSFLSEGAGLFMFETFADLKYIKPVIHWLKDKSDAAVFVSF
CVNGYGYSKYGIRASRLLEDASQMEEIDGIGFNCGIGPGHLWQVMHRLRLPEDKIITAFP
NSGYPALRSGRTDFKDTRQYFGQRMKDIAELGVNLLGGCCGTNPSYIEAVEKTVDFRQTA
VRHIPEASPVILKKAAVTNPLLQKMQSGQKVNAVELDPPYDANTDRIMEYANSLKTAPVD
IITFADSPMGRGRVDSILMGAKVLHETGLPVMPHIACRDKNAIALRAGLLGAYVNGIRNF
LVVTGDPVAGGDRGDITGVFDFNSITLMQFLKEMNQEHFREEPICYGGALNQGRKNLDAE
IRRMGKKIEAGASYFLTQPIFSIEETERIRQIKKEVNTRILCGIMPLVSYRNACFIRNEV
TGIQVPEQVVRSFDPGMSKEQGEEAGVRIARRMMDELKDVADGYYFMLPFNRAYLAARCL
RDDGE
>A0A1C5KW00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MGNTKHTKEQIRERIQQKKLLFDGAFGTYYGGKYDTKQLPELANLEAPERVKEIHTEYLE
AGAQILRTNTFAANSFCMDMSKEQIEETLRSGVRLAREAVTAWRERTGETKEVYIAGDIG
QIPCDALAQKDTLCREYEEICRIFLEEGVDFFVFETFSEMEELLPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGAIKEIDAVGFNCGVGPSHMYRILQTLYKPADKFLTALP
NAGYPQMVTGRMIFTGDNREYFVDRMQQMIALGVDMAGGCCGTTPEYISDLAGKLDFTQY
PQTQEKAEPEKKQAGTEDHSFYHNKEAEGGKKLIAVELAPPAGIDDEKLMDAAHLLQRSG
VDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGIH
NFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFAQAPVSYGGAINQGRRNLE
VEIGRVKKKMAAGATFFLTQPISTKESADRVRRIKEETGARILCGIMPFVSLKNATFMKN
EMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVITMTEDFADGYYFSFPFNRVTMLEK
ILD
>A0A6J4STV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Sphingomonas sp|TrEMBL
MNRLQQFSRPNPLFAEARGDIAVSFEFFPPKSETMAETLWGSIQTLAPLKPRFVSVTYGA
GGSTRERTHATVQRIIQETDLTPAAHLTCVGASRSEVDEVARAYWDAGVRHLVALRGDPP
TAGERYEAHPQGYANAAELVAGLKAVAPFDISVAAYPELHPDSSCRQSDLENLKRKIDAG
ADRAITQFFFSADSFFRFQDAVADAGMDVEIVPGILPVSNVAQTRRFAGQCGTGIPDWLD
AMFEGLDDLPSARQLIAATVAAELCGQLYAGGVRHFHFYTLNRAELSYAICHLLGVRAHA
>A0A6L6TFR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. TDA1|TrEMBL
MSLLKTALHEKTFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTLAIGDRVGSPLDLS
PLDALASFSSPVPALPHFSGKDRERHHLLAQLQRMDADGLDQLLLLTGDRLPGHQPAERP
VRYLESVAALQLARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DASKHQEAQTWMNRQPHPKPLLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAEAAVSK
AHAQARSVDRLALQVIGVKLMGYAGVHVSGIHELKQLLALEQRIEHWQAQIHSLEQWAPA
WAASWQVPGLPAVVFHPPSASWRQGESKVSASSKEKARYHLLHASHALLFSRSNWLSQAF
GWAVRQPLWATARGARVLHGVERALKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTSLNRCEFGDRECIHSVKYRTAKAARQTAVLTERLIPCIEVQTRHRSSWPAWFAAQAP
HRLKPCSKPRTQPES
>Q2JD76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia casuarinae (strain DSM 45818 / CECT 9043 / CcI3)|TrEMBL
MAAVRSLSTQPTTMGEYLATGRASFSFEFFPPKTPDGERQLWTALRQIEALHPSFVSVTY
GAGGSTREGTIRVTERIATDTTLTPIAHLTAVNHSVAELRRVIGNYAGVGVRNVLALRGD
PPGDPQGTWTAHPAGLRHADELVRLVRSVGGFCVGVAAFPDKHPRSVDFDSDARYLVGKF
DAGADYAITQFFFGADDYFRLVDRVRRLGCDKPIIPGIMPVTNVAQIVRMAQLSGAAFPP
ALASRLQAVADDPAAVRAIGVEVATELSRRLLDGGAPGLHFITLNRSSATREIYQAVR
>A0A5C6LXA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga pinensis|TrEMBL
MGHTLADKIKSGHSRLVFYSLTPPKITTNQDRIAEIAQAQAERISALDIDALILYDIQDE
ATRTDQERTFAFIPTVLPEQYSRDYFHQLKVPRIIYKSIANLNAEQFTHWLTNNNDIQHS
VFVGASSQQQIEQTNFSLSDAYALRQQYSPNLLIGGVTIPERHAKKGDEHIRLSGKIGQG
CSFFVSQCVYNVNDTKDVLADYYYHSRETNQTPAPILFTLAPCGSLKTLQFMEWLGIKVP
RWLYNDLKHSKDILQASIDTCLNVASELLEYADKKNMSIGFNIESISIKKDEISASIDLL
DQVLKLSRQSLKTAPERPSGKVVEEVRMPLY
>G9A7P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium fredii (strain HH103)|TrEMBL
MSPDINPFDPSAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDTIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHEATPTETLVAERLGHLREGIEENQQQLAEAAAH
HPH
>E6U6U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ethanoligenens harbinense (strain DSM 18485 / JCM 12961 / CGMCC 1.5033 / YUAN-3)|TrEMBL
MKISTILQQDKIHVSCEIFPPKQSGKLQQTEEVVKELAAVHPDFISVTYGAGGSTKANTV
RLADIVQKHGIPALAHLTCVSSTQEMVRDTLAELRQNHIENVLALRGDLPQDGNVPVQQQ
YRYASELVCEIRSQGDFCIGAACYPEGHVESTSREEDIAHLKEKVECGCDFLTTQMFFDN
NVFYSFLYRILAKDIRVPVVAGVMPVTNARQIARICALSGAALPPRFSNMADRFANDPAS
MRQAGIAYATEQIIDLISNGVRAIHLYTMNQPDVALKIFENISEIIK
>A0A417X489|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. OF09-25XD|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A1C5PTT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKIPQIFEAKKKEGKPVLSFEIFPPKKEAALQNIDETLSLLCDLHPDFISVTFGAGGSTA
NNKTVEIARKIKNEYGIEPIVHLTCLHYNKDEIRSILDQLKEAGIENVLALRGDMNPNIP
VKHDFHYANELVEYIKTQGDFSISGGCYPEKHLEAPDAITDIRNLKRKVDAGVDHLVSQL
FFDNEVFYDFYEKTRIAGIDVPIDAGVMPVTNRAQIERMVTMCGATLPVKFQKVLHKYEN
NKEALLDAGLAYTINQIVDLIASDVDGVHIYTMNNPAVAKRICDGIRNLV
>G9A8E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium fredii (strain HH103)|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMEIQLFQTVADLSSFAPAFQTVTYGAGGSTKAR
SLTTVKRMIGEMGLRNTAAHLTCVGAPKAEVDAVIDEFVACGARHFVALRGDPQGGIGSA
YQPFPGGYESSAALVNALRARGDFEISVSAYPEKHPESSDVAADIDMLKRKVDSGATRAI
TQFFFDNDDFERYLERVRRAGVQIPVVPGILPINNLTQVIRFAGLCGSKVPEAIVSRLGH
LDDQPEERFKEASHIAAEQIVDLARRGVRDFHLYTMNRSPLIAAVCDLVGYGRRPANHTA
APSYRAVATA
>A0A3M1DEY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon|TrEMBL
MSVIERLKNGPLLSVEIEPPRVGASLNDLFVLLDDLVEKGIHQVNITYHAEQPHTDGIAR
RKKPGTTGIAGAIIGRYGATLTTVPHVICTGFSAAETQEYLIDLAYLGVTDVLALRGDPY
RDAQGRFCAFTPKENGHRYARDLVRQLSDLRQGKYLGGEVGVPLDFCVGAACYPEGHRES
PSRTQELRWLKEKVDAGVDYLVTQAFYNNELYYRFVDEARAAGINVPIIPGLFPLTKRHQ
LSLLQKVFGVQVPRQLAEQIESSSVEDRVLVGSEWTVQQALQLRENGAPGIHLYTHNGAP
VSNIITVLQSKNEFHEPHSPTG
>A0A6J7UTS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MPRIADILTQASGPTLSVEFFPPKTPVGDANLQQTIEDLRAVPLSFVSVTYGAGGSTRDR
TRDLVVDINEHESYPAMAHLTCIGHTKPELEALLDDYDRAGVHNILALAGDPPADGSPAD
GDFTYALELVELVRARGDHFSVSVAAHPELHPRSQDTKGDRLHLAQKLSVADFGITQFFF
SAPDYFQMVEELSALGCDTPILPGIMPLTNPEGVRRMAKMSGATIPEDLAVRVEGAGSVD
EAQAIAVEAALELSQELLDGGAPGLHLYGLNKSEIVLRLVDQLNLL
>A0A540UZM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ureibacillus terrenus|TrEMBL
MGLLDALKDKVLVADGAMGTLLYSYGLEYCHEEMNIERPEIIEKIHSQYIQAGADVIQTN
TYGANRIKLARYGLEFKTAEINQSAIEIAKRAAEGHKVFILGSIGGIRGIRKVDHTLDEI
LEAAREQAEVLIGGNLDGLLLETYYDFEELTATLAMLRTMTDMPIIAQVSMQEPGVLMNG
MKLNDALKQLESLGADVVGVNCRLGPYHTIQAFEEVEIPERAFLSAYPNASLLDIEDGRV
VYESEVDYFARAAVELCKEGVRLIGGCCGTTPKHIEAMKKKLAHFRPVEKKAAKPHREIV
IREAEPRSFEPLHEKAKRERSVIVELDTPKHLEIEKFIEGAKALYEAGADLIMMADNSLA
SPRISNLAMGAILKLKYGIRTMPHITCRDRNLIGLQSHLMGLNALGLHDVLAVTGDPTKV
GDFPGATSVYDVSSMELISLIKQLNEGISFSGKSLGKKANFSVAAAFNPNVRVLDRAVSR
LEKKIEHGADYFITQPVYTKEKIVEVYEATKHLETPIYIGIMPLTSFKNAEFLHHEVPGI
KLSDEVLERMKQVSGNKEEETRVGLEIAKELLDTATEYFNGIYLITPFMRYELTIELLQY
IQQLDEQNKGVKANG
>A0A6J6LR53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARIGDLLATGRTFSFEFSPPKSAAGSLSLGRTIAELEPLAPSFVSVTYGAGGSTREHTR
DTVLWVRKETNIPPMAHLTCVGHTRAEIADIISTYTDAGIVNVLALAGDPPKDPADARPS
DYVYATDLIEHLKEIGNLCIGVAAHPEGHPRSPDLATDRRHLADKLRAADFATTQFFFDL
DHYLSLVNDLADLGITKPVVPGIMPVTNIAQVERMAELSGAAFPAWLRERLESGTSPEDV
RRIGVEAATELSAQLLEAGAPGLHFYTMNKSTATLEIYAQLGLPVV
>A0A6J7GRS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MNTPPTAHRVGETLRKGGRTYSFEFFPPKTDEGEQQLWQALAELEPLKPTFASVTYGAGG
STRDRTVRITAQMAARTSLAPVAHLTCVGSTITELEEILAEYAAAGVSSVLALRGDPAAG
PGTPWVSTPGGIDHADQLVELIRQTGDFGIGVAAFPDGHPESSTRDQDAQVLARKQDAGA
EFAITQFFFRASDYFDLVERAATHGCDMPIIPGLMPVTNVAQIQRFAALSGAAFPADLAE
QFETISDDAAAVQQLGVDVATDLAAELLAQGAPGLHFYTLNRSSATRQVYEALALRDV
>A0A6J7DJ43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSALQEKLENTKETVFTAEFPSIDGAGMDKVVKNAERLAPWFDAVNATDNPAAHAHASNT
STAIAIKMHGLEPIMQIVCRDKNRLAIQADMMGAALHGIQNISLLTGDDVTAGDEPEARR
VFDVDGPQAINIARILTTGKYLSGRKINPAPEFYISAVENSSAPPFDYRIQRALKKHQAG
ARYLQLQISYHPDRLEAFCTGVAKIAPALHLIPTIVLVKSAKPMDFMNEKVPGIDIPKDM
INRVASASDQSAEAYQLTVDLAKHALTLPGVRGLHVTDFRHDDSLASFMHELGRKPRN
>A0A6J6NGZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSPTRTAPSLGAVLAGGGHSFSFELFPPKTDAGEQALWQTVRELEALKPTFVSVTYGAGG
STQDRTVRITKQIAEHTTLLPVAHLTCVDASVDDLRRVIAQYSDAGVNTIMALRGDPIAG
PESRWVQHPGGLQHADELVALVRSLGAFSVGVAAFPEGHPESGDFEEDARVLAAKQDAGA
EFAITQFFFRAEDYERLVTRAAAHGCTMPIVPGLMPVTNVAQIERFAVLSGAQFPSELAD
KFGKIKDDQGAVHELGVEVAADLGGKLLAMGAPGLHFYTLNRSTSTREVYEALGLNEV
>A0A7V7GUK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas laoshanensis|TrEMBL
MSIETKKPVSFEFFPTKTEAGHEKLIATGKALAAENPEFFSVTYGAGGSTRDGTLKTVLQ
LDQEVQVPTAPHLSCVGDSKEDLRSLLTLYRESGIKRIVALRGDLPSGMGQASGELRYAN
ELVEFIRAETGDHFHIEVAAYPEAHPQARHFEADLENFIRKAKSGADSAITQYFFTADCY
FYFVDRVRKAGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLESYGDDSESIAA
FGTQVITELCQRLIDGGAPSLHFYTLNQAEPSLAVWRNLHGK
>A0A6L4YNK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MTFELSIEFFPPQTSEGMEKLRTTRSRLAVLKPEFFSVTYGAGGSTRERTLATVMEIAAE
GHNAAPHLSCIGSTKEGIREMLAIFIERGIRRIVALRGDLPSGMVDAGEFRYANELVEFI
RSETGDRFHIEVAAYPEWHPQAKSPREDLLNFKRKVDAGASSAITQYFYNADAYEHFVSE
IRALGVAVPIVPGVMPIASFSKLARFSDACGAEIPRWMRRKFESFGDDADSIRAFGLDVV
TELCQRLIERGAPGLHFYSMNQAGLTLELCKRLGR
>A0A7X8P596|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. ERN07|TrEMBL
MNASYDQLREARTALDTPLFAGLPGDIAVSFEFFPPKTDALMAQLWDVVETLAPLQPKFV
SVTYGAGGSTRDRTHGTVARIIKDAKLPAAAHLTCVDATKAEIREVAESYWEAGVRHIVA
LRGDMGAPGVPFTPHPEGYANAAELVAGLKEIAPFEISVAAYPESHPDSPSVTADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAAACGAA
IPAWMDGLFEGLDTHPASRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPKAPALEKAA
>A0A2D5V0T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon|TrEMBL
MDDSGRYEFSIPVRRNGGLPSARSSFVEQYAKGFQISLEVCPPCDEYKTGLDDILEGVSA
LNDRVLSLTDLPIPYVFVTCGALGKGEEGTLNTAVGLQEKGFTPVVHVTCKYKGREEIAE
YLDSLLSEGISHLLVIRGDKSEGESRLYIPEEGFQHASDLIEFVHGYDSRFVVAGAAHPD
GHPEAVSRNDDFRYSFHKFMGADHFVSQFTLYPNNFGDLFLKVNRLRNRNGMFPVTMIPS
LIPVSSAKKIEKLSPVCGFKAPDDVAGYLRTNPVGEGCDSFADFQTRLYQVYERCCSGVH
IYTRNFFKSSVRYLRSVEEAKYRSERKVRSSEGLSRVC
>A0A3S9M4Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cyaneochromogenes|TrEMBL
MALGTASIRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGDWVPHPQGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWETDVRHFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAAGCDTPIIPEIMPIASVKTLERIPSLTNASF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A5C7K3U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MNHTEISVEFFPPQTPEGVEKLRATRAKLAELKPEFFSVTYGAGGSTPERTFAIVREIAA
EGLSAAPHLSCIGSTRESIRAILDEYKAENIRRIVALRGDLPSGTGDAGEFRYANELVEF
IRKETGDHFTLEVAAYPEWHPQARSPADDLAAFVKKVKAGANSAITQYFYNADAYFHFVD
SVRKQGVDIPIVPGIMPISGFSKLARFSDACGAEIPRWMRRKFEGFGDDADSIKAFGLDV
VTELCERLLAGGAPGLHFYCMNQAALTTEICKRLKIA
>A0A3D3U1N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MEYSVEFFPPQTPEGMAKLSATAQKLQNSGRFAYASVTYGAGGSTRDRTFAAVDALQAAG
WDVAPHLSGIGATEASIVTILDRYRAAGIRRLVLLRGDLPSGVVDPGPFRYARDLVAFVR
ARYGDTFWIAVAAYPEYHPQAKHATADLDAFAAKMAAGADCAITQFFYNPDAYAHFSDEA
ARRGVTQPIIPGIMPITQFFRLARFADSCGAEIPRWIRRKMEGFGDDVASIRAFGHEVVA
RLLERLRALGAPGFHFYTMNQAEPTLALL
>A0A3S0F2F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MKPEISIEFFPPTTAEGADKLRATREKLAALKPAFFSVTYGAGGSTRERTFSTVKEIAAA
GHEAAPHLSCVGSSRDSIREILQEYADAGIRRIVALRGDLPSGAGAAGEFRYANELVEFI
RAETGDRFHIEVAAYPEWHPQAKSPKDDLDAFKRKVDAGANSAITQYFYNLDAYLYFVDA
VRKMGVDVPIVPGIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDSEAIRAFGLDVV
THLCEKLLAEGAPGLHFYSMNMAGPTTEICRRLGLTA
>A0A1F9BJG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_50_11|TrEMBL
MIRKKGNLLKGVVDAVNVTDNQTSVVRMSSFSACLILKEMGFDPILQMVCRDRNRIAIQS
DILGAAALGINNILCLTGDHQKFGDHPKAKTSLTWTRSS
>A0A372JMS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura logoneensis|TrEMBL
MRRPNPDRAPTIRELLASGDPSFSFEFMPPKTAEAARTLWRTIRELEPLNPTFVSVTYGA
GGSTRDNTVDVVERIATETTMTPVAHFTAVDHSQAELRHLIGRFASAGVRNILALRGDPP
GDPTGEWVRHPEGLEYASDLVRMIRSYGDFCVGVAAFPYKHPRSRDIESDTRYFVEKCRA
GADYAITQMFFRASDYFRLRDRVAAVGCDVPIIPGIMPVTRLSTIERSEQLSGAPFPEEV
RARFEAVRDDPEAVRRLGIEHAAELCRELLDQGAPGIHFITFNRSTATREVYELLESAGY
GARGSVPPITA
>A0A2P8DI27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Murinocardiopsis flavida|TrEMBL
MVETMLGSPTRPTTAPATLTRPRSIRDLLHTGTPTFSFEFFPPKTPEGQRKLWRVIREIE
ALRPDFVSVTYGAGGGTRDRTVDITENMATDTTLLPVAHITAVNHSVRELRHLIGRFAGA
GVTNMLAVRGDPPGDPMGEWIKHPEGVEYAEDLVRLIKESGDFSVGVAAFPYKHPRSVDV
DSDVEYFVRKCRAGADYAITQMFFDADEYLRLRDRVAARGCDVPIIPEIMPVVKIATVEM
SEKLSGAPFPPRLAAQFERVADDPEAVRQLGIEQASRLCERLLDEGVPGIHFITFNQSTA
TREIYQQVAPDRTAEAVGARP
>A0A0M4Q3E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. AL041005-10|TrEMBL
MQFGPCGGVRPDHGCELGTGPCPFAAAPLVPWTGPAGRSVRPSAFDGGGPVVLTDLTSPP
YDPVALRRIVATTAAGCDAVLVGQHHDAPDFPPTMLAALVREAGARPWVTLTCRDRNRVV
LEQDVAGLAAAGADAVFCVTGDARGPGVRPDVTQVFDLDGTRLAALAAAAGMAAVVPEAP
DAAPVALRPARLAEKQRAGAGAAVLNHAASPARVARFTAAARAHGASLPVVAGVAVFTDE
PGARTLAAFPGLGLDAAAVEAVLRAPDPVEAGIAAATAEALQLLAVDGVDGVNLSGRGTS
AGDDAAAEIKAEIGRRIRREVASAG
>A0A4P7QNZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. PAMC28499|TrEMBL
MTQTDRARHDAEGPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFVSVTY
GAGGSTRERTHNTVARIAKETPLAAAAHLTCVAASKAEIDEVADAYWEAGVRHIVALRGD
PPEAGTAFQPHPDGYKGAAELVEGLRKRHDFEISVAAYPETHPDALSAQSDIDNLKRKID
AGATRAITQFFFEADTFFRFRDTVAAAGIDADVIPGIMPVSNFAAVQRMSAMCNTDVPAW
MGRLFDGLDQHPAARQLVSATLAAELCRNLYMGGVRDFHFYTLNRAELSYAICHLLGLRP
QVAVDA
>R6KQR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:265|TrEMBL
MIFFLAVFRPKVTSYIETIYKMLEELKGVSPDYISVTYGAGGPATSNRTLDIASLIKNKY
NMEPMAHLTFKQELCR
>A0A2G6FEH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus propionicus|TrEMBL
MHIHEIVQQSSPGVSLEFFPPKSRQDWPKFLNVASKLKVLDPRFVSVTYGAGGSTQDNTL
EICQELIANCGYEVMPHLTGVAADVEKINAFLQALAPMGIDNVLALRGDRPGNFSGSDDE
LFTGFPYAADLVAHVRKNFPRLAIGVAGFPEAHIEAPSIAADLEVMKKKADAGADFVVTQ
LYFDNRVYFDYVDRLKQRGVQIPVIPGVLPIRSLTSLRFILEMCNARVPGQLINALGKAD
ADGGNKAVYEIGVAYARKQVKELLDGGAPGVHLYTLNHADMCLEVMDGLL
>A0A260TE45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 14-2686-1-2|TrEMBL
MDRLRSDGAARIPFSVEFSPPRDEAGEARLWRAVREFEQLQPAFVSMTYGAGGSTRDRTV
RVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRGISNILVLRGDPPGDPLGDWEK
HPDGVEYADELVTLVRELGDFHVGVASFPEGHYRALNLEQDTRVLVNKLRAGAEYSITQM
FFDVDDYLRLRDRVVAFDPEQGAKPIVPEIMPITSLRTVRRALALSGSALPKALDDRFTT
AAGTGPEEDRAAVREVGIELATQIGERLIAEGAPALHFITLNFAKATREVLTNLGLCAAR
V
>A0A6H3J8M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. MDB2-10|TrEMBL
MSTPTDSARTRRIPFSFELYPPKTDAAASALAKTIDHLAAAGPDFLSVTYGANGSSRRSS
LDVLSRILRTTNVEAMAHLTCVGSTHDEANRLIREFLDAGVRSFLALRGDPPAGTKEGEA
FLGDFGSAAELVQLIHRVQAEKSPYRETIIPGIPAARAVKPGHEKVRIAVAAFPNGHPRS
RSSAQDIDTLLAKQAAGANLGITQLFFHADHFLSFVQRAREAGVLFPILPGIMPVTSPAR
LRRIIELSGEQMPADLSIRLEIEPTKEGQREIGIQHAVDLASQVIAGGAPGLHLYAFNQH
ETVLEVLDGCGLLGAPAPVRTPTALPTIV
>A0A7T1Y4M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas campisalis|TrEMBL
MSTPYPLGISFEFFPPNTDAGREKLMGVRDALAERNPRFFSVTYGAGGSTQSRTLNTVRA
VREAGVTTAPHLSCIGSEKAQLRDLLAQYREEGIDSLVALRGDLPSGMGGIGELRYANEL
VEFIRDETGDHFEIAVAAYPESHPQAPSFERDLENFARKVKAGANLAITQYFFSADAYFH
FVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIARFG
TEVVSGLCQRLLEGGAPGLHFYTLNQAEPCLKILDNLNGTLAAR
>A0A5P1FS56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asparagus officinalis|TrEMBL
MKIIEKIEKIQASDEGKVVFSFEYFTPNYLRTGTRRLFVLAPWPPSAAHGPVLRHHLAAA
DPSRHARRARRRMQGELVDTMNAPPRGAGCRGMRIDHRAWTPARGGEGFSSGLDLVKYIR
KKHGDYFGICVAGYPEAHPSQIPDGAEVATEEGYAADLDYLKKKVDAGADFIITQLFFDA
QVFIKFVKDCRRIGIRCPIIPGILPITTYRNFKFMTETCKTKVPKEVRAAVDAAKGDDKK
LAEYGVELATKICREILKETGVRALHFYTMNKEAPALGVLRNLGLVAAPAAAENGKVAAV
KM
>A0A531JN11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
KTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTRERTARTVKRILNETTLTPAAHMTCV
DAARDQVDAVVREFADMGVTRFVALRGDPAAGVGTAYRPHPDGYANGAELVGAMKSAGDF
DISVSAYPEKHPESPDFATDFDMLKRKADNGATRAITQFFFDNDLYERYVERARRAGIYI
PIVPGVLPVHNFTQVANFSARCGALVPAWLAERFEGLQNDPQTHALVASAVAAEQVLDLV
ERGVSDFHFYTMNRADLVFAICHMIGIRSHEAEATGSAAA
>A0A530ZEW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETAIPAAAHLTCVGATRDEVDTVIQDYKSIGINRFVALRGDPASGVGG
PYRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A1E5P0R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces subrutilus|TrEMBL
MREILASGRRSYSFEFFPPKTEAGERTLWNAIRRIEAFAPSFVSVTYGAGGSSRDRTVEV
TKRIAAETTLRPVAHLTAVGHSRAELRHIIGQYADAGIRDVLALRGDPPGDPKGAWTPHP
QGFTHAHELVSMIRKLGDFSVGVAAFPERHPRSPGWTEDVRHFAEKCKAGADYAITQMFF
HVEDYLRLRDRLDSIGCLTPVIPEIMPATDARQILRFAELSDARFPDALARRLEAVQDSP
ADGHKVGVEYATAMAQRLLAEGAPGLHYITLNRSTATLEIHQNLGVTS
>A0A2E9RAJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MEQVLRSGQLAVTAELSPPDSADPQEVYKRAALFAGHVDALNATDGSGANCHMSSVGVCA
LLTRAGYSTVMQISCRDRNRIAIQGDILGAAAMGVRNILCLTGDGVQAGDQPDAKAVFDF
DSISLLQTVRYMRDESQFLSERKLSTPPDLFIGAAANPFSPPVDYRPQRLKKKIEAGAQF
IQTQYCFDVPGLKDYMREVCNLGLHERCFILAGVGPLASARTAKWIRENVPGVHVPDDLI
TRLEGAVXQQQEGVKICIELIQQIKEIDGIAGVHVMAYRQEEMVAEIIQKSGVLNGRSPS
VPSMXGTFKT
>A0A2M8Z280|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] celerecrescens 18A|TrEMBL
MKIKDILSQGKPTLSFEVFPPKTEDKYESVEQAASEIAKLKPAFMSVTYGAGGGTSQYTV
DIASALHHQHHVTALAHLTCVTSTKDKVHQVLDELKEAGIENVLALRGDMPTDAPAKKEY
HYASELIREIKEAGDFCIGAACYPEGHVESASKTIDMDYLKQKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVIAGIMPVTNVRQIIRSCQLSGTYLPSRFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANGVNAIHVYSMNKPDVALKIKENLSEIL
>A0A3R9DD67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum litoreum|TrEMBL
MKVIEHLEKANGASLFSFEILPPLKGDTIESIFKNIDPLMEFNPPFIDVTYHREEYVYKE
LGDGLLKKQVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPEKDGHAYASELVTQIENLNKGRYLDDDLQNSSKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKNGANYVITQMFFDNQKYFEFVEKCREEGITVPIIPGLK
PISTKKQLNLIPHRFKVDLPDALVKEVVNCKSNAEVRQVGVEWCIAQSKELQQKGVPILH
YYSMGRSTNIQKIAEAVF
>A0A529IEI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
APPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILCGVGPLAS
AKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAGVHVMAYR
QEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVKTAH
>A0A0X1L461|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cholerae (strain MO10)|TrEMBL
MTLGHREYKMGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKTLQ
PKFVSVTYGANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQ
NIVALRGDIPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRK
VDAGANRAITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVP
NWMVKQFEGLEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGV
RPQA
>A0A2M8ZBE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] celerecrescens 18A|TrEMBL
MKLSNILKNKTTLSFEVFPPKRTDSIQTIYNTLNALHELNPDFISVTYGAGGNGNGHTTC
EIASTIKNQYNIESLAHLTCAGLTKEDLLSQLENFKQNGIENILALRGDILDPNQPRGDF
SYASDMITFIKEYGDFDITAACYPEGHTESKDLIEDIDNLKRKVDSGADQLITQLFFHND
YLYRFQERCSLAGIHVPIEAGIMPVINKKQIERMVSLCHVELPSKFIAMMNRYENNPDAM
RDAGIAYAIDQIVDLVVHGVNGIHLYTMNNPYIAKKIHEAVHQLIRE
>A0A2U9S447|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum ramasamyi|TrEMBL
MTAPTSAQPSVSFEFFPPKSEKMEQSLWQSIRRLAPLSPGFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGRYEP
HPGGYAYASDLVAGMKRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDVYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPAKLAETFEGLDD
DPETRHLVAATVAAEQCQELQARGVHDFHFYTLNRSDLTTAICRMLGVKAKAPAAGPVAG
>A0A439TTB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFAEMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALLPAWLAERFD
GLQKDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A368LAQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. JB110|TrEMBL
MTGKDVPGLLEAQHAIPQGTRINVTFLGNEDLEMRVAAAKAVKEAGFVPVPHISARRIGS
EAQLREFLAALQEVGASEHVFAVGGDPATPEGPYDSAYDLIRSGVLPEYGVKEVSISGYP
EGHPDISDELLWEHLEKKASSLKEQGLGAVILTQFGFDTEPVENWIDRVRGLGIDATIRI
GTPGPAGIKRLLNFARRFGIGANAMIVKKYGFSLTNLMGTAGPDRFITDLADRNAANPAS
GDVKLHFYTFGGLKATAEWAEKFAAKVA
>A0A5C6AI62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrimarina colliarenosi|TrEMBL
MRLPDIYAANKFALSFELFPPKTEAGVEALFGHAQTLVGFKPAYITCTYGAGGSTQDRTL
EIAARVRKEFGLPVATHLTCVGRTADQIRDYLRRAAEADVTNVVALRGDPPAGETEFRFT
EGGFHYANELVAMIHEDFPAMGVAVGGYPEVHQEAPSPEADLDALKRKVDAGAHAIITQL
FYDNEDFFRFRDRCNAAGIDVPLIPGLLPVTNVSQVKRIASLCGAGLPVAFLSQLEACGD
DAAAQFDVGVEQATVQTQGLVDAGVPGIHYYVLNKSEAASRVLKAVRLGG
>A0A7Y9JAT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides panaciterrulae|TrEMBL
MESGRGRSMADLIGGGERSFSFEFFPPKDAAGEEQLWRAISDLEPYRPTFVSVTYGAGGS
TRDSTVRITGRIARETSLTPMAHLTCVGHTRAELETILDRYAEAGVHHVMALRGDPSDGP
RAPWTPTTGGLTYATELVELARSRGDFRIGVAAFPEGHPTAASLDADADVLAAKARAGAE
FAVTQMFFRAEDYFGLVERVRARGVDLPILPGIMPILNLSAIRRQGELIGADVPASVVGR
IAAHDGDPAAVRNEGVKIAVELCEELLAGGAPGLHFYTLNRSRATLEIFEALNVTV
>A0A369BRG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fontibacillus phaseoli|TrEMBL
MRPDLRKRWENGVLVGDGAMGTYLYKFGFPVGISYEELNLLQPEVIGDVHSHYINAGAEL
LETNSFSANYYKLSKFGLESQVEGINRAAVRIARQAAGSEAYVAGAVGSIRGGRRVNVTD
QELSKYYEQQIAALLSEGVDALLFETFYDLGEMRLALRRARQLTEIPAICQFAVDQVGRT
LDGYTISDAFSLLRDEGADVLGFNCHSGPKGIMSVMSGLDGPLNVPLSVFPNAGLADYVD
GEYVYGATPDYFGECARSFADLGARLIGGCCGTTPEHIAATAQALQGYQAKPLQQGAPLP
KPRESVILGNPGGSSDHGQLRGITELVKERHTVIVELDPPRDLDIGKFMEGAAALKEVGV
DALTLADNSLAVTRMSNMALGHLVQLKLGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPGASSVYDTTSFEIIRMIKQLNEGVAFSGKPLKQKAKFVVGAAFNP
NVKHLHKAVERLEKKIASGADYIMTQPVYDPELIVAIKQATAHLDIPIFIGIMPLASGKN
AEYLHNEVPGIQLSEEVRKRMEGLQGPEGRAMGVEIAKELLDTAMEHFNGIYLMTPFMFY
EMNVALTNYVHEKSKQKSAYLSRS
>A0A8D0ALC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sander lucioperca|TrEMBL
NQSELDGRLPLGLTCSLVQRGDGSWQSCKSDSSGASNSSESSKESSRSSTPVLDVDRSDR
LRDKMRRRMESGDRWFSLEFFPPRTASGAVNLISRFDRMGTGGPLFIDITWHPAGDPGSD
KETSSLMIASTAVNYCGLESILHLTCCNQTKEKISGYLAKAKHLGLKNIMALRGDPVGAD
WEEEEGGFNYATDLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADF
IITQLFFRADTFLKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVI
EPIKDNDAAIRNYGIKQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPR
RPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYY
LFYLKSKSSKDALLKMWGDELMSEESVYEVFTCYITAQPNRSGHKVMCLPWNDEPLAPET
NLLKDELEKVNRRGVLTINSQPNINGKPSTDPIAGWGPAGGYVFQKAYLEFFTSSENVNA
LLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWK
DEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWKVIDDMFELLD
ATPEPLDATPEPLDATPEPLDATPEPLNEGAASE
>A0A2M8SAQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium CG_4_9_14_0_8_um_filter_58_9|TrEMBL
MRIANPHHKKQKVNMTNKFVELLSSQTLLADGAMGTMLHARGVGFDQCFDELNLTDPAAV
ADIHKAYIDAGAQLILTNTFGANRYKLNKHGLESKVAEINRAGVELARRAVAASFKDVWI
AGDVGPLGMRIAPFGRVQPDEARAAFSEQIAALAEAGADLIVIETMSDLYEIQEAIRAAR
DVGATFMVTQEGMQQNGRRRASPLPIVASMTFTRDDRTVLGDSPEKVARTLAEAGADVIG
VNCSGGPAQLLRLLKQMRQAVATSETPHSAHPYFWVKPNAGWPEQIGGRIMYPADPAYFG
DYALAFCEAGADIVGGCCGTTPRHIAAMRAALDKFPAGCKTELLETPEVLETSEVSTEIE
PPSQLAQKLADGKFVIAAEMDPPRGLSTHKLVAGASLLAEAGADVINVADSPMARMRMSA
WAVCDVIQRQVGVETTLHFPTRGRNLLRVQGDLLAAHALGIHNVFVVMGDPTAIGDYPEA
MDNYDLVPSGLIKLIKQGFNLGMDHSGTSIGQPTDFFVGAALNLNPPEPESEIKNLHRKA
KNGADFFLTQPIYRPEDGPAFLEKYAALHGSLDRPVLAGILPLVSLK
>A0A7G7G755|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adhaeribacter swui|TrEMBL
MKVTEHIANAKKTLFSFEILPPVKGTSIQSIYNGIDPLMEFKPPFINVTYHREEYVFKER
ENGLLEKISIRKRPGTVGICSAIMHKYNVDAVPHIICGGFSREETENALMDLNFLGIDNV
LVLRGDSIKTEAQFRPHPDGHAYASELLKQVCNLNQGIYLDEDIANPVPTNFCAGVAGYP
EKHSEAPNLEIDLKYLKMKVDMGAQYIITQMFFDNQKYFNFVKACREYGINVPIIPGIKP
LTVKNQLRMLPNLFHIDIPNDLVQAIDSAQTPQAVRQVGIEWATQQCKELVQFGVPCLHF
YTMSKSEATAAIAKEIF
>A0A5Q2EMF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O157:H7|TrEMBL
MNFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7C7MIL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIRDKVKKPQRPVVAYEILPPREKDGTLNSYAETISSLLSQTHIDAINIPEVHDEIGRG
DRPVTNQKRGEPREFGMLLQDIVGIEAIINRVVVHESYEEQMRWIEETNTTYEIENMIIV
GGESSKVDYPGPTVNEMLQSIAKRSNSNGGDIFCGGIAIPSRKNESKNLIRKSEHGSEFF
TTQVLYDAENIIKMINNYQSRCNELDTFPRRILLSFAPVSSQKNIEFLKWLGVEIPDDTE
RYLKGRPGSMTERSLDVAVEVLNEILDFITVNNLKVPVGLNVEHIMSYNFQSSVEMLQEL
ARIYREFCIKTQQYS
>A0A1F5ASX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium RBG_16_63_16|TrEMBL
MAESSIRHHIENQILHVELQTPKRSSEDIEKDLRTFEEKYRKVMEAGWIVCITDNPMGLL
SYGAMETIDILGLPVHPEQLVVHLNTFHPKKEFDEILDAVKAAGGKYLLAVSGDGNQRLH
RLEPAEVGIEATTVTSVEILKYIDREYPGKFTTGVAFNPYEPQDHELEKMNRKVDAGARF
IITQPIIGRDERLEGLKPFGLPVILDAWMSKKLHLLSECVGHEIPEGTPYDPIENLKELH
RNYPDYGLYLAILGFKTQYPVLQEIWK
>A0A4V2MPN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter psychrodurus|TrEMBL
MKITDHIKSAKGKTLFSFELLPPVKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QGNGLLQKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHCYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMNTDFKYLKKKVESGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNNEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKKIAKAIF
>A0A2D8PGY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISDKIKEYKKQKKVFYSFEYFPPKTDFGMDNLYSRIDRMSSLGPAYIDITWGAGGSTA
ERTLDMSKTIQKYFGLDVMMHLTCTNMSIKLIDEVLSEAKKSNISNILALRGDPAEGSNE
WRKENQAFNYGVDLVHYIRKNFGDTFFLAVGAYPETHQEQSDPDLDITYLKEKVDAGVDI
IVTQLFYDIDKFLLFRDKCLSKGIDIPIIPGIMPIHNYSRFRKFTQFCKVNIPENILKKL
EPIRNDDASVINFGIEQGADMCEKLVKEGVPGLHFYTLNLEHSVKEILNSIGLISDNKAN
RELPWRQSSDEIRKLSEDVRPIFWSNRPISYLTRTENWDDFPNGRWGDISSPTFGELNQY
HAIRAGSQSNEIRNKRKKIWGEPQSI
>A0A423M675|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVERLQALGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A120FX52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMTTAKQLASFSPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0F2CBD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. SA39|TrEMBL
MSSETETSGTPRVPFSFELYPPRSESSEEALHETVRRLAAVGPEFLSVTYGAGGSTGGRS
LDVLRFIREHTDVEPLAHLTCVGNTYAGAAALIREFLDAGILSFLALRGDPPQGHDEPFL
GDLESAAQLVQLIDRAQAERAPYEESPVPGFPGAARVSPRRKVNIAVAAFPKGHPRATHR
TQDVEALLAKQAAGATFAITQLFFHQDDYLAFVERARAAGVTIPILPGIMPITSPARLAR
VLELTGEDLPSELSIALEVEPTAEGRREIGIEWAARLTREVVAGGAPGVHLYAFNQHDTV
LTVLAEAGILPALRR
>A0A162MYC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermovenabulum gondwanense|TrEMBL
MGASVTPFYDPVELQIIKMQKKIKAGAKFFQTQAVYDPQILKNFKQKTEEHHIQTKILAG
IIPLKSPGMANYMNKNVPGIHVPEEIIERLRKAQDKQKEGLKIAAELIQQIKEQNLADGV
HIMAIGAEENVPLLLDLSNL
>A0A0J5S696|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribacter muris|TrEMBL
MSYAKEIDLLNQSVADLNGNINVSFEFFPPKNEKMENLLWESIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKTIQQQTGIISAPHLTGIDATPDELRQIAQDYWDSGIRHIVALRGDEP
PGYTKKPFYASDLVALLKEVADFDISVAAYPEVHPEAKSAQSDLLYLKQKVDAGANRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMPKMYQGL
EEDQTIRNLVAASIAIDMVKVLSKEGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A2T6CSI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spartobacteria bacterium LR76|TrEMBL
MHIEDTLRESETTFSFEFFPPKTPEASENLYQTIRELEAYRPDFVSVTYGAGGSTRDLTH
DLVLRIKRTTSLNPVPHLTCVCHTEAEVESILTRYAEEGVGNILALGGDPPVREGYDRSK
DAFQHAADLVSFISRFNASGKHADPRGFGIGVAGFPEGHPATPNRLLEMDYLKAKVDAGA
NYIVTQLFFDNRDFLDFRDRCSLAGINIPIIAGIMPITSLGGMRRMAELAAGARFPAKLL
RALQRGQNDPAAVERIGVHYATEQCADLLENNVRGIHFYTLNRSDATRRIFDNLGLRSVK
A
>A0A5Q4FEH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiaceae bacterium|TrEMBL
MKTQKQHERTFSFEFFPPKNDEGAKKLKDTWTELAKLEPRFFSVTYGAGGSTQARTLETV
LDIHKNSGVDAAPHLSCIDSTAEQMRGILQLYKDNGLRHIVALRGDLPSGMRDPGEFRYA
NELVEFIRKETGDHFTLEVAAYPEFHPQAPNALKDLQNFKRKVDAGADSAITQYFYTAEA
YFRFVEDCEKLDINIPIVPGIMPITNYKQLARFSDACGAEIPRWIRKRLEAFGEDTASIK
AFGEEVVTDMCAQLLKAGAPGLHFYTMNQAGPIQAIWKNLGLKPEPK
>A0A0E9ZMP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 10-1B|TrEMBL
MSLLKTALREQNFVCVMEFVPKASAERFAAMQAIMARGHLCSWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQATPKPMLACLMSLTHGRATMLDHVAGVTVTPSMREMLEAETAQSK
TFAQARSVDRLALQIIGTKLMGYAGVHLSGIHELKQLLALEERLEHWQAQVHSLEQWAPA
WHASWQMPGMPAVTFHPPQASWRQGESQVDASFREKARYHLMHGVHALLFSRRNSLSKAF
GWAVRQPLWATRAGVQVLHTLERSVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVGQTAVLTERLIPCIEVETRHRSSWPQWFAPPTS
RRLSPQPAPRTQPES
>A0A323TAG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipaludibacillus keqinensis|TrEMBL
MSFKQEIQEGILIGDGAMGTLLYQKGIDGCFEELNVTDPEQVRRVHKQYIEAGADIIQTN
TYAANSLKLSRYHLEDRVQELNTSAVKLAKQAAGDDAYVFATIGGVGSILHKEFDLADIK
DSLIEQADVLLKTEVDGFLLETFYDVEELTQMVRYLRSKTTKPIIAQVTLGDIGVLQGGM
SLAEALKLLESEGADVVGLNCRMGPYHMLRSLEEVPLLEKATLCVYPNASLPNVRDGRFF
YQSNPTYFGDMTESLVSQGVHLIGGCCGTTPEHVKAIREAVDKNNLIPITEKEVKEKGTP
SVVVNTPNVQDSLPGFTKKRRSVIVELDPPKALSHAPEFMKGAEALKNAGVDAVTLADNS
LASARIDNLSLGSLIKQQVGARPLLHVACRDRNMIGLQSHLLGLHTLGIHDVLAITGDPA
KVGDFPGASSVFDMASMDLIRLMKQLNEGISFSGKDLGAKTSFTVAAAFNANARRLDREV
MRLEKKVEAGADYFMSQPVYSEERFEEIYEATKHLPVPVYVGIMPLVSSRNAEFLHHEVP
GISLTEEVRQTMAKHHGDREASQREGLALARSLADAAMEHFPGIYLITPFLRYGMTVELT
KHIITMDKNITAQSSFR
>A4YLY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. (strain ORS 278)|TrEMBL
MTDLATAVTDGHSAIIRPKISFEFFPPKTEEMDRTLWSSIERLAPLEPSFVSVTYGAGGS
TRERTHATIARILKETALLPAAHLTCVGASRQEIDEVVDRYHEVGVRHIVALRGDPPGGI
GTPYHTHAEGYQTSPELIAGIKKRHPDVEISVSAYPEKHPESRDFDADIDMLKAKVDAGA
TRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARGFVTRAGTTVPDWLAE
KFDGLDNDPETRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPKSV
NKVAA
>A0A7W2ELC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. FT3S|TrEMBL
MDNPNFSIEFFPPKTAEGADKLRVTRAKLSELHPKYFSVTFGAGGTTQRGTLDTVLEIMA
AGEQAAPHLSCVGGTRESIRAILAEFKAHNIRRIVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPETHPQARSPQDDLLAFERKVKAGANAAITQYFYNADAYFYFME
QCGKLGITVPVVPGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTALCQRLLAGGAPGLHFYSMNQAAPTTALWQRLV
>A0A7W4CFC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. SG41-7|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>F2SNP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892)|TrEMBL
MSQALRPLFVTVTWGAGGSTAARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEET
KALGIRNILALRGDPPRSEEYNIDGEDDSNKDFNYAVDLVRYIRKKYGDYFCIGVAGYPE
GHADESHPEVQDLLKDLPYLIEKTQAGADFIMTQLTYDIEAYKKYEALLRNHESGTFKTI
PIIPGLMPIQNYHTLTRVTKLSHAKIPPQILAKVEACKADDEAVKRVGVDVVSDLVENIK
KVATPGHRGFHFYTLNLEKSVSFILERCNLIPPSSEAPSDSELDFESAVYAASGASNGVA
TPDGRSTNVNRLRASSMNSQPHNRVIVDRLTRASDRSERSSTVHETSAQTAGYPALNPPN
RNTALQISEGLGSLGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTAQVARKLWGTP
TSRDDISNIFKRLLSGELHVVPWSEGGAGEEGGLNPETATIKAELLKLVEGRGWWTLASQ
PAVNGVRNDHPVFGWGPRGEGFVFQKAFVEFFCSGDDFHSKLKPLLQSYGHDEFAWFATN
AKGDFQSSTSPETSTQPPTDPSEVPFDADPLTEMDNGSVNAVTWGVFRGKEIVTPTIIEA
VSFRAWGEEAFGIWEEWRRVFPRGSPSEKLIREIKDDAWLVCVVGQRFGAGGDVGKESNE
EDGKLLWKVLAGE
>A0A5Q4HEE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrospira sp. PLM2.Bin9|TrEMBL
MNRFRTACLNPKEFVITAEVAPPKGGDPTHMIEMARGLKNRVHGVNITDGSRAVLGMSSL
ASCVILQHHGIEPILQVACRDRNRIGLQADLLGAHALGIRNILALTGDPVKAGDHVNAKP
VFDFESVRLLQAINKLNNGMDWNDKNLPHGGTDLFPGAAVDPQSPSFSGLQSRFYRKLKA
GACFFQSQLITDFERLYKFMNQVACDTDKPILAGIFLLKSAKNALFINKYVPGVNIPDHI
IHRLEKSSQPLEEGIKIAAEQVQIARQICQGVHLMAVKREDLIPKILDAANIPPLL
>A0A1C5YJ32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MATVKLTELMKERQLLSFELFPPKTDKGMENLPGTIEHLCEFKPEYISVTYGAGGGNVGT
NREVCQMVKKAGTVPVTHFTVIKNTKEGIKDQLETYLSEGVDHILALRGDFPRGENSTGG
DFNYATDLVKFIRKEFGDKFEIAVAGSPEGHIACRSLDADISVLKMKQDNGADYIMTQLC
WDMEQFARWQDKIRKAGVTMPIDVGIMPILDQAATINMALSRNGCVMDRELSRLISKYWI
FPNPFDKAPFDDALEQKKEDFKKAGIEYTIKQIDKYRALGVEGIHLYALNKWKDVSEIIK
ESGMRTLV
>A0A4T2C1V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Subtercola vilae|TrEMBL
MTALRFEIIPADGVADRLARTFADTSAVTLTVTSLPQHGVERTVRASIELARLGFGVVPH
LSARAIASRGELESILLRMHDSGIGEAFVVSGDGGSPAGSYSTSLELIHDIVDRAPQLSL
GIAGYPEGHPHQSPDQLSKHLLERAPFVDKVVTQLCFSAETIGTYAAQLRASGVTAPLWV
GVPGALRRSRLISLSARIGVGSSLGFLKRSAGVAGGLLRSRDFDPAPFIAELAAEPQLQR
VGVAGLHVYSFNEIERLPEVQSLVARTHGAAAE
>A0A7K8SM19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nyctibius bracteatus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A385YZU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cavernae|TrEMBL
MSQERRYSFEFFPAKTEAGHEKLLATARQLAAYNPDFFSCTYGAGGSTRDRTLHTVLQLN
GDVGVATAPHLSCVGDSKDDLRDLLNQYREAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGEHFHIEIAAYPEMHPQARSFEDDLSNFVRKAKAGADSAITQYFFNADSYFY
FVDRVQKLGVDMPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIASIQAYG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3A3G705|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noviherbaspirillum sedimenti|TrEMBL
MTNSSSVQQNFSIEFFPPRTPEGVEKLRATRAKLAALKPAYFSVTFGAGGSTQAGTRDTV
LEIRKEGYDAAPHLSCIGRSREELRAILDEYKAHGIRRLVALRGDLPSGYGAVGHDAGEF
HHANELIEFIRAETGDWFHIETAAYPEMHPQAKSPQEDLRNFVRKVQAGADSAITQYFYN
ADAYFRFVEDARAAGVVVPIVAGIMPITNYTQLTRFSDMCGAEIPRWIRLKLASYGDDTE
SIRAFGLDVVTGLCEKLLAGGAPGLHFYTLNQAAPTTAIWQRLVRQA
>A0A6N7ISN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofundulus thermobenzoicus|TrEMBL
MKTESKLEKLLERGEFVVTAEIGPPKHASAEGIRHHAHMLKDYVDATNITDCQTAVVRLS
SIASAVHILDCGIEPIVQMTCRDRNRIAIQSDLLGAYSLGMRNLLCLSGDHQKFGSEPTA
KNVYDIDSIHLIYLMRRMRDEKLFFSGEPIKDHEPRFFIGAVANPFADPFEYRVDRLEKK
VEAGAEFIQTQCIYDMERFERFMEMVRERGIHERVHILAGVTPLKSWRAAKYLQTSVSGM
IVPDEIVERLKKAEDPKKEGVEICIEQIKHIRNIPGIHGVHIMAIAWEEVVPEIVERSGL
YPRPKVE
>I3VV58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterium saccharolyticum (strain DSM 8691 / JW/SL-YS485)|TrEMBL
MPKSINLCQKLKNKQFVITVEISTPKGADISNSIEEARKLYGIADALNITDCPMANMRMS
PIALAHLLQNHLNIETIFHLTCRDRNLIGLQAELLGAYALGVRNILALTGDDPKRGDVPQ
ATGVYDVDSVGLVKIAKSLNDGFDYSGNKLESSTNFCIGTTANPNDLRSESIEKLKTKIE
SGASFIQTQPVYDEEILYRFLDAVKQFDIPVLVGVLPLKSYKMAVNLNEKVPGIEIPEKI
IDRLKNGEKGEGTKIAIEFINKIKDKVGGVHIMPLGKTDIVVDIVNGVKNIGQNDIEEVL
>A0A7C9GTG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium LSUCC0115|TrEMBL
MQISLEFFPPKTESAQASLADTARTLARLHPQYVSVTYGAGGSTREGTLSTVTQMQGIFQ
KVAPHVSCIGASTEEMTSLLTDYQSKGISRLVALRGDLPSGYGQGGAFAHAEDLVCFIRQ
SFGQAFEIEVAAYPEIHPQAKTAQDDLRHFVNKVKAGANGAITQYFFNSDAYFRFVDEAY
QQGIDIPITPGIMPITNYSQLARFSDACGADIPRWIRQRLAGFGDDVASIRAFGQEVITD
LVDQLVTAGVPGLHFYTMNRAEPTLAIVDALGLKGQPG
>A0A6G3CZE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5914|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPGADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PPELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A4P8M894|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLYQRNRLRRRPGTVAVAAAIQNKYNMTVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGHHHALELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIHWLKKKVEAGAEYAVTQLFYDNKKYFDFVERVHQAGIHIPIIPGIKP
FKKLSQLSMVPKTFKVDLPEELTQEALKCKTDEEACKVGIEWCINQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A8J6JVK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubritepida sp|TrEMBL
MDHISPTSSTLERWLAGPRIPALPAPRDMAPPKLSFEFFPPKNEAMEKSLWECIRRLESL
APRFVSVTYGAGGTTRSRPHATVSKIVAETSLTPAAHLTTVGATKEEVHEVAREYWAAGV
RHIVALRGDPPVGAHEYTPHPGGYAQAEDLVRGLRDVADFEIIVGAYPETHPTAVSADAD
IDYLKRKIDAGATSAITQYFFDTDIYLRFIDRCLAAGITAPIIPGILPVTNFAQVSKFSA
MCGASVPGWMGELFEGIDGDATTRQMVAAMVAAEQVRLLQANGVDEFHIYTLNRPDLAYA
VAHLLGARAKPAGVAGA
>A0A0E1XDY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella pinnipedialis M292/94/1|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>F7V9Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter tropicalis NBRC 101654|TrEMBL
MSLSRLSVELIPRSTEALLDDVASVKALFPAADTLNVPDLMRFPLRSWDAAALIRPHFAR
VVPHIRAIDIAPDAPLPGADQPGLEEVLVVHGDPPADLSHRTYPNSTESIIRRYKKEAPH
LRIYAAFDPYRRAPWQELEDVARKKEAGAEGFFTQPVFDLKLFDLCREWLRDETVFWGLS
PVIGPRSRSYWETTNHVVFPKDFEPTLEANIQFAQTVLRHLSQEKGRAYLMPLRVKLDQY
LPPLLEALA
>A0A2N8HB03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia muciniphila|TrEMBL
MHLRERLQSAAGPSLSFEFFPPKNEQAAAALYQTIRELEPYHPSFVSVTYGAGGSTRELT
REVVLRIQHESRIPTVPHLTCVGHSRDEVWNILDQYAQAGVRAVLALRGDPPRGAADYNR
DADAFRHAADLVTFIREYNESGRHPDPDGFAIGVAGFPEGHPATPNRLREMDFLKAKVDA
GADYICTQLFFDNHSFLDYRERCLLAGIKAPILAGIMPVTSLSGMNRMAELSGGTCFPAR
LLKALKRAGSNPDAIQEVGIQYASSQCAELLDSGVAGIHFYTLNQSRATREIYRNLGLKD
SLQLLEHGEDK
>A0A0N0AS73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix sp. NRRL B-16348|TrEMBL
MTSVVERLHGESPVFSVEFFPPRDEAEETILWRAIRELEAFDPAFVSITYGAGGSQRDRT
IRTTGRVAQETTLLPMAHLTLVDHSVAELRNVIGWYAAVGVRNILAVRGDPPGDPNGEWV
AHPEGLTYAEELVRLCRELGDFCVGVAASPYGHPRSTDLDSDTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAARGCDTVLIPGIMPLTTPRTLAKTVELSGASVPDWMARRLDPHA
DDPAGFRAAGIDLVTEMGERLLAEGVPCLHFYTFNRSKATREIVGRLGLVPARAA
>A0A0D6P4F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidisphaera rubrifaciens HS-AP3|TrEMBL
MNHAATDARGTLDRWLTSPRVSAIPMPRGDLSPPLLSFEFFPPRTDALEAQLWACIRRLE
GLRPRFVSVTYGAGGTTQARTHATVARLVSETSLTPAAHLTCVGAARGEIDEVARRYWDA
GVRHIVALRGDPPAGQAYVPHPNGYAYAADLVAGLRRVADFELSVAAYPETHPQAAGQDA
DLDNLKRKLDAGATRAITQYFFDTGVYLRFLDRCLAAGITAPIVPGIMPVSNYAQAARFS
AMCGASMPDWIGRLFEGLDDDIETRRMVGAVIAAEQVRLLQANGVDEFHFYTLNRPDLTY
AIARILGVRPAADAASGAEGPG
>A8AV20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288)|TrEMBL
MVRHHTPSLSFEVFPPNPAVGNEKIIQALREMQDIAPHYISVTASNNKFNIEETTVRLAD
FIYNDLKIPTIAHLPAVYLTKEMVSDTLQALDKVGVHRILALRGDIFPDVAPKDDFKYAT
DLIEYIKEEAPHFDIIGACYPEGHPDSPDRVSDIRNLKKKVDAGCSSLVTQLFFDNDRFY
DFQERCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLKS
AGLAYAIDQIVDLVTQDVAGVHLYTMNNAATAHHIYQATHTFFS
>A0A3N6NGN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. RP6|TrEMBL
MTDVTTPATADGHLKRPAISFEFFPPKTEEMERNLWDTIKRLAPLEPKFVSVTYGAGGST
RERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPVGGIG
TPYSSHPDGYQSSAELVAGIKKRHGDIEISVSAYPEKHPEARDFDADIDTLKAKVEAGAT
RAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWFAAK
FDGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRVKTAQ
KAA
>A0A2Z6CEE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktothrix agardhii NIES-204|TrEMBL
MNRFRTACQTLDEFIVTAEVAPPKGADPSQMIEMVRLLKGRVHAVNITDGSRAVLGMSSL
AASIILIHHGVEPIYQLACRDRNRIGLQADLLGAQALGIRNVLALTGDPVKAGDHPDAKA
VFDLESVRLLQAIDKLNQGKDWNNKTLPDGATDLFPGAAVDPQSSSWSGLKSRFERKIEA
GAQFFQSQLITDFDRLDKFMTEIADSSKKPILAGIFLLKSAKNARFINKYVPGVCIPDSI
IDRLEQAKHPLEEGILIASEQVKIARELCHGVHIMAVKREDLIPEILDLAGIKPLF
>F8FB90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus mucilaginosus (strain KNP414)|TrEMBL
MKNTMNSGRKDEPPGSGGQQMLKEKIQGRKPGIITYGITPPKQNHPPEKIAEIAKKQIDR
IADIGIDGLIIYDIQDEADRIDQERPFPYLSTVDPTTYSKEYLGPLTVPHIIYRSVGKYS
ESELSGWISSDPGQDRFSVYVGASSSKQEVRLSLPQAYELSRRLNDTLHFGGVVIPERHL
TRKDEHLRMISKMNSGCRFFVSQATYDVEASKNVLSEYYYTCQEQGLEMVPILFNLTPCG
SLKTLEFMKWLGISVPKWLENDLMHSNDILDKSVRLTLKIMEELMDFGLEKGIPIGCSVE
SVSTRKVEIDASVQLLKDVKQSMESRLLQPQSL
>A0A0V1BG71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella spiralis|TrEMBL
MNSSYNLQMKLKSPAYQRAVTDFGVYFEEDSFLSLMASLEAVELKATGHDLNSAAKKSTD
EIYRSLIDRIKENISSGRRFFSLEFFPPHTTEGLINLLKRVDIFANSQPLFVDVTWVMRS
DPASEKVTSSSSLADCILNFCLLDTMLHITSVQYNEKTVLFNLERAKKIGIRNILALRGD
ISDDANVTTTDFQYACQLVRFIRSHYGDYFTICVAGSYLLYVYCLMIFLFARIILQDLLN
LKAKVDAGADFIITQLFFDEMHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSK
IVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRKLLNREHHVVPGLHFYTLNQEKSILE
QIGFWKKAPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYLCRTRDWKQFPHSRWGDVG
NPAFGNLKHYLFSCIDQMDDSCALDMWDKELSTLEHVRDIFCNFIARTPNRHGHSVRRLP
WNENHLDPAADILKNELIYYNSNGILTINCQAAVNGLPSSDPIFGWGEANGYIYQKGYLE
FFASSTCTTILLNHVQNFPSINYHAINFDGSFETFNYDEDATVALTWGVFVGQEIVQPTV
ANAASFRVWKDEAFDLWQRWAGLYESGSIGRKLLQKIHDDYRLITLIDNDYPQPCSLSAL
LRAVISDYWGKKLDDG
>A0A1G1IX28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium RIFCSPHIGHO2_02_FULL_40_19|TrEMBL
GGKKVSFKNAFDSGKFVVTAEVGPPKGTDIKEMLHHAEMLKGKLDAVNVTDNQSAVMRIC
SMAICKLLLDMGLEPILQMTCRDRNRIGLQSDLLGASVLGIKNVLCMTGDHPNAGDHKEA
KPVYDIESVQLLGIVNSLNNGKDMMGNEMKGSTNFFQGAVVTPEANPVEPQLMKFEKKVK
AGAKFFQTQAIYDIEKFKEFVKFARKFPVKILAGIVLLKSAGMANYMNKFVPGIRVPQDL
IDEIKAAGKEGALDTGINIAARHIKQ
>A0A1G4A3Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium RIFOXYA1_FULL_69_10|TrEMBL
MTPISFEFYPPKTDEQRTQLDRTVARLKREAPEYVSVTFGAGGSTLSHTPETIQRLRREY
ELPAAPHITCMGGSREEIRGLLKLYRALGAKRLVTLRGDLPSGMVSPGDLRYANELVEFI
RNETGDHFHIEVAAYPEMHPQARDAHADLAHFKRKVEAGANGAITQYFYNADAYFRFVDD
VRAAGIEIPIVPGIMPIANFSQIRRFSELCGAEIPRWVAQRMLAYADDAQSIRAFGAEVV
AQLCRRLVDGGAPGLHFYTLNLAKPTLNVLDRLR
>A0A4V6NIY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2568|TrEMBL
MATGLPSTRPGSRPTIRELLSTGQPSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVSHSRDELRSVIGAYAGSGVRNILALR
GDPKGGPSQPWVAHPEGLNHAVELVELVRSLGDFCVGVAAFPDKHPEAADLEADAQVLAA
KAAAGADYAITQMFFGADDYFRLIDRAATLGCDMPVLPGVMPVTNIKQIERMAELTGMAL
PKPVTDRLNAVAEDPAAVRAVGIEIATELSDKLLAGGAPGIHFITLNRSTATRQVFRNLQ
SAVV
>B4J2M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila grimshawi|TrEMBL
MSAAPRPTLLRHVAAVAQRRCCYCCCCCCYWRQLSQRSHQVRNISQIMHAIEGTLSVTAS
TSLPIEPCFHFTAGQVANCGKQPRLGDLVANKTRIGEFFYGIEITSNTRGIITCVDFNQF
LPVLPTFISLAWLAPYWQVEPIGQVQTLQLTRALESYIPAMPHLSTYRLSEQHYDDFFDL
NFDNLLAVRGDELHEDQAYKYTRQMVAHARRARGKEMTIAVAGHPEGHANDLELGPQDID
KDLTYLKEKIDCGSDFIITQICYTPEPLIEFLRKVHRVGIEAPVMVGVVVPNSFKSYLQM
ERVSKIRMPKEMRAEAEKYKNDDAKAQSYFVQHALSLIQRVLDADLGMHGIQFYTMNNFE
PVFEVLGELRRRGILKESSPNAASGAA
>A0A7W8YXZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter cryoconitis|TrEMBL
MKITDHVTNAKGKTLFSFELLPPVKGKSITDIYDAIDPLMEFNPPFIDVTYHREDYIYKQ
HDNGLLEKVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTREETENALIDLQFLGIDN
VLVLRGDARHADSTFIPTPGGHAYATDLLGQVNDMNHGKYLFEDHSAFQTDFCIGVAGYP
EKHFEAPNLKADFKYLKQKVDMGAEFIVTQMFFDNAKYCDFVAQCRANGINVPIIPGLKP
ITSSKQLISLPKIFHIDLPEDLTEAVQECKNEKDVKEVGIEWMIQQCKELIKVGAPVLHF
YTMSNPEPTKRIARAVF
>A0A6B2ZXZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7909|TrEMBL
MGPGTDRPTYSFEFFPPRTAQGERTLWQAIRRLEPLGPDFVSVTYGAGGSSRDRTIEVTK
RLVTETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPKGEWTAHPDG
FHHAYQLVELVRSLGDFTIGVAAFPERHPRSADWDSDIRHFVAKCRAGADYAITQMFFDV
EDYLRLRDRVAAAGCTTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAQHRPDI
AYEIGVAHATLMADRLLAEGAPGLHYITLNKSTATLDIHRNVMSTRSLHAS
>A0A653MAQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas sp. 9C|TrEMBL
MLPLSFEFYPPKTDDQRSQLDRTARKLAAHAPEYVSCTFGAGGSTLSHTPETVRRLTQHH
GLDAAPHLSCVGGSRAEIRELLTLYRAIGCTRIVALRGDLPSGMGRPGDLRYGADLVAFI
RSEFGDTFRIEVGCYPEIHPQADDARTDLRHFKAKVEAGADAAITQYFYNADAYFHFVDS
ARRVGIEIPIIPGVMPISNFSQLRRFSEACGAEIPRWMQRQMTAHGDDADAIRELAADVV
TGLCERLIAGGAPALHFYTLNLSKPTQAVLARLS
>T0CTQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paeniclostridium sordellii (strain ATCC 9714 / DSM 2141 / JCM 3814 / LMG 15708 / NCIMB 10717 / 211)|TrEMBL
MSLLKETLESGKFAVTAEMAPPKGTDLSHLIKCARAVKGRVHAVNVTDFQSAVMRTTSLT
TCKLLKDEGLEPVLQVTGRDRNRIAIQGELLSAGVFGIKNMLALTGDHTIVGDHPKPNLY
LT
>A0A4D6XZS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MYIISKYHKDIIDQKIKNISNNTRCSFEFFPPKNTILEKNFWCSIEKLSKLKPKFFSVTY
GANSGEHKKTYNFVKKIYEKTNITTAAHLTCIDSTSDELKEIAKNYWKNGIRSIVALRGD
TLKKNVKHKMYASDLVLLLKNIADFDISVAAYPEMHPESKNPKFDLINLKRKIDAGANRA
ITQFFFNIENYLRFRDNCVKNNINVEIIPGILPIYSFKQLQRFSSITNVKIPDWTFELFH
GLDNDLITQRNIGFSIIIDMIKTLSYEGVKNFHFYTLNQSDIVYTACHMLGL
>A0A3A9D825|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium D16-50|TrEMBL
MIKDMLENKRTVSFEIFPPKKDGEFKAVFEVLDALGRLSPDFVSVTYGAGGSRSGKTIEI
ASYIQNTLGIDAIAHMTCVGSTKDALLSVTQALREKDVTHILALRGDRPRDMSDEQFASR
AFAHASDMMDFLRENTDLCMGGACYPEKHFESFSMESDLNNLKKKQDAGAKYFISQMFFD
NDYYYSFLEKAGKKGITAPICAGIMPITSAKQLGTTITLSGSSIPKALSDLVAAYGDSSE
DMRKAGIDYAIRQILDLRENGVNGIHIYTMNKAKMAAEIMAAL
>A0A1Q7ZB48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_20CM_2_68_14|TrEMBL
MTRPIAPVLRLEEAFRSGLPVVTCEIATGDGADPDEVLRRVRLVRDHVDAVNVPDNTAGI
VHMAAWAAAALLAREGVDPIMHVTCRDRNRMALQSDLLGAAALGVRNILCLTGDHMVHGD
HPGAKPVFDLDSLQLVSLATVLRHGRYLSGREIRPAPALFPGATENPFAPPYDFRPLRLQ
KKVEAGARFIQTQITFNVKRFAAFMERVRDLGLDRTVPILAGVAPVRSARSARYMRERVP
GMEVPDAIVRRMEQAGSERARREDEGIRICVEIIEQLREVRGLAGFHLLPIHWEEAVAEI
ASRARLTPARASLSAHVEATARDAGSADARRDDSEGALLNRHREHRA
>T0D2X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paeniclostridium sordellii (strain ATCC 9714 / DSM 2141 / JCM 3814 / LMG 15708 / NCIMB 10717 / 211)|TrEMBL
MVGNQLKGAPEFYLGASVTPRYTPIEVQLLKMKKKINAGAEFFQTQAVYDIDTMRDFRRH
TKDMNTKVLAGIIPLKSPGMAKFMNANVPGIYVPEELIDRLKSVGKENWVNEGIKIAGEL
IKQLKEENLCDGIHIMAIGAEENIPAILDAANI
>A0A250BHK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brenneria goodwinii|TrEMBL
MSFFHANQRESLNQSLAELQGQINVSFEFFPPRTSEMEETLWNSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCVDASRDQLREIAQDYWQSGIRHIVALRGD
LPEGGGKPEMYAADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSMFE
GLDDDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAVA
>A0A3M5FCZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi|TrEMBL
DKSAPTKYVFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTY
GAGGSTRDRTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGD
LPSGMGMASGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANA
GADSAITQYFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWI
RKQLEAYGDDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A436KYN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.002.06.1.1|TrEMBL
EARLWETVTRLEPLKPKFVSVTYGAGGSTRERTARTVKRILTETGIPAAAHLTCVGATRD
EVDAVIQDYKSIGINRFVALRGDPASGVGEPYRPHPGGYENGAELVAGLKTIADFDISVA
AYPEKHPQSPDFATDIEMLKRKVDNGATRAITQFFFDNDLYERYVERVRRAGIYIPIVPG
IQPVHSFKQVANFSARAGAHVPGWLAERFEGLDKDPQTHALVASAVAAEQVMDLVERGVG
DFHFYTMN
>A0A525W1D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. CG24B|TrEMBL
MSREPQRLIDVLNRGTFVVTVEYNPPKGTNISAILENAKQLVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKD
AKPVYDLDSVQVMQLVQGLNNGKDMVGNKLDGSTAFTIGAAVTPEADLVGPVLAKFEVKV
KAGAQFFQTQAVYHPDVFASFMKQVRPFNVKVLAGILLLRNAKMAEFMNANIPGMSVPSE
MIDELKAAGEKAEDVGVDIAVRTIKAVRPHCDGVHIMAIKATHRLAEIITKAELG
>A0A4S8Q7L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycomyces buryatensis|TrEMBL
MTLGVASVMPTQAAKIGDLLRSGTPRFSFEMFPPRTEKGEETLWRTVRALEGLGADYVSV
TYGAGGRTRGKTVETTDRIISDTTLLTMAHCTAVDHSVAELRNLIGHFANVGVRNILALR
GDPPGDPRAEWIEHPDGLKQARDLVELIKSSGDFSVGVAAFPEGHPRDVDWEAGVRHFVE
KCRAGADFAITQIFFDPEDYLRFRDAVAAAGCDIPIVPGIMPVTNIKQIERFAVLTGMDF
PAELAERLRAVEDDRDAIRDIGVEVATDMGRRLLAEGAPGLHFTTLNHSRSTRRVWQNLN
GAGNPKALA
>A0A354WXM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp|TrEMBL
MNVIDLINNSKSTAFTFEILPPLKGNSIQKVYDVIDKLREFDPKYINITSHHSENIYKTQ
PDGSLRKVNIRKRPGSVAIAAAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LLLRGDVKTLEPVKDPENYHEHATDLQQQVNQFNKGIALDGSRIEGIETPFCYGMACYPE
KHEEAPNMESDIYYAKEKVKNGASYLVTQMFFDNSKYFAFVDRCRKEGIEVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFAAELRKCKTDDEAKEAGIEWCIGQCKELIAHGVPSLHFY
TMMASESVRRIAKEIY
>M5FLI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. STM 4661|TrEMBL
MIGRQRDENPAGIDLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPRLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDQIVKRLEGAEDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A7L0UUM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptocoma aspasia|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDTDRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A8A0RJ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Koleobacter methoxysyntrophicus|TrEMBL
MSAKNKFGEKILSGEFTVTVEINSPKGTDVFHEIKGLEQMVEMVDAVNICDCPMANMRMS
PITTAHIVHELTGIEAIPHFTCRDRNIIALQSELLGAWALGIKNILAITGDPPQRGDHPH
ATGVFEVDSAGLVKLAKELNRGFDLSGNELRGSTDFIVGVACNPGAEDLNAEIDRLKQKI
DSGADFIQTQPIYDPDVLLRFRDRTSNLGVPILAGILPLKSHKMAVHLNDKVPGISIPLK
YIERMKKGPEEGVAIAMEFMEQILPYVNGFHIMPLGNTATAIELLNYIDTIKVRKVI
>A0A847DMX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sumerlaeota bacterium|TrEMBL
MKIYELFKQKRPVLSFEVFPPKPSLSFDSVFESVSTLASYKPDYVSVTYGAAGSTRGRTL
DLAQMIKIKYGVEALAHTTGVLLDEVQLDKLLDEIDIRGLDNILALRGDVPQGGSDADLK
FHASDIVRLIRKREGRFCIGVAAFPECHPQSKSVEDDLKYLKQKLDTGADFMVTQMCFDN
ELILRFRDRVRQLGITQPMTIGIMPVFAVGQIAHISSMCGAVIPDELKQTMEKYSDDSAS
MLKAGIEFASKQITDLIAQDFEGIHIYTMNRPELAHGILVQTGLRNL
>A0A7X5URB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora amisosensis|TrEMBL
MSDFAEAVRERLLVCDGAMGTMLHAAGNSLDRSLPELNLSNPDLVSTVHESYVDAGADIL
LTNTFGASRPRLAEHGFSGDIGEINRAGVRLARQAARRAGRQVFVGGSVAPAVSTGRRNQ
VGAADRAAAVREQVLALADAGVDLLVLETFGYLDELAEAVLTAATATGLPILAQATFTSE
GRTPGGQTPREVATALAELDVTALGVNCTVGPQRTLAVAEQLRRHTTLPLSAQPNAGLPR
RVRGRRFEYSLDHDYFARYARRCAERGVSIVGGCCGTTPGHIRAVAAAVSDLDVRRTSRG
RAARPPAAAPEEQGGLAQRFAEGGFVVAAEIAPPRGGVADEAAELATEVRQRGAELILVS
AAGGAGAQLSSTSLALHLQSEVGIETIATVTTWDKTIMTLQADLLGAHAFGTRTVVCETG
NPPLRGDYPNADGIWEVDSVGLVELVAGLNDGRDCDGLSLATKTSFHIGARCNPGAEDVD
AEIARTRAKIAAGAQFLITRPVYELTTLRWMVAELSDEGVPILVAVSPLSGFAEAEFLAY
EVPDVTVPLSTLSTLAQRERAGDDGRGVGLLLASELVEQARSLADGVLVVVREHDVDAAA
RLLAAATTAPG
>A0A1H6RK70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter sp. SG02|TrEMBL
MFLNKIKSQESGVVLYGITPPKADTTAERVAEIAEKTIERLAALDIDALVVYDVQDESAR
TKEERPFPFMNSLDPLHFASGYLGSLDVPKIIYRPAGKFSAEELSEWLEALHKQSFYPVF
VGVPAPDFPVRTSLPEAYKIWRKNEETSVIGAVTIPERHKILQDEDVRILDKMECGVSYF
ISQCVFNLEYAKQVIEDLALRCGSQQIAPPTIIFTITACGSEKTLQFMDWLGINVPEEVK
EDLRQSENILERSVNICLDIASELTAFCMERSIPFGFNIESVAIRKAEIEASIYMASQIS
QMLKDKGVRKVAGAEQALRTT
>A0A0Q5UMC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf198|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGLSFEFFPPKSEKMETQLWEAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPVDKVAAA
>A0A1M6A528|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWP2|TrEMBL
MKIIDILKQDKMSLSFEVFPPKKETSFENVKAATEAIAALGPAFMSVTYGAGGGVSHFTL
DIAKNLKEKFNIPMLAHLTCVSSSKETVHQRIEDMKAAGIKNVMALRGDLTPELIEKGRD
NCDYHYAVELIRELKAADADFCIGAACYPEKHPESANQAEDIKHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGILRNVSAILGKNFAC
>H6BSG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656)|TrEMBL
MADDDRLPTLLSNLPPSSNYFSLEFFPPKTSLRFSNLQSRLARMAAALRPLFVTVTWGAG
GSTATKSLELAEVCQRQLGLTTVLHLTCTNMKRSMVDEALETAREVGIRNILALRGDPPR
EEYRDTNDGGSGGSGTDSNEEFVWAVDLVRYIRHKYGDYFSIGVAGYPEGHADESNPIAG
QQSVEHDLPYLVEKVAAGADFIMTQLTYDIDAYAAYEKRLRDYVDPKDGKKLFATIPIIP
GLMPIQSYQIIKRITKLSHAKIPEDISRRIEAVKSDDEAVKKVGVDILSELVEQIKGLPQ
PDGVPRGLHFYTLNLEKSVAFILERTGLIPPISEPEPEEPSSDSSSDSDAIAADNATPTI
SPPTLSLNGTAAAENGVARPPGPTGLVKRRTSSVNAQPHNRVILEREQQEQRHRQRKEKQ
QQQQQQEEAAAAAADADREKMLKQHIAPDRGTGIPASDPTRKHNLMISEGQGSLGREATW
DDFPNGRWGPSHSPAFGEIDGYGPTLKVGPITARRLWGHPKTRDDVTALFRRVVVGELEA
VPWSDEIDVADDTTTANGAAGASLRAETQVIRQELLAMIEKKGYWTLASQPAVDGVRSED
ETFGWGPPGEGFVFQKAFVEFFCDRHEWETRLKPRLLKYRSDQVSWFKTDANGAFESSEE
IENEKKKKTETKTNGGVDDHDTTTTTTNGTATTTSVTATGVNAVTWGVFRGKEIVTPTII
EAESFRAWGEEAYSIWSEWRKCFPRGSDEERFLERMRQESVLVNVVGHNYIGGHDGAGGE
LWKILLDE
>A0A0H4IYY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilales bacterium MBRS-H7|TrEMBL
MKASSFSFEFFPPRTQEGEEKLKRTLKNLSVFNPEFFSVTFGAGGSTKDKTIGVVQSIKD
DGYNAVPHISCITSTKDEVMDLITSYKNKGINRLVALRGDNPSGIAGYGDFHHASDLVEF
IRTNTGDYFHLDVAAYPEFHPESESSIDDLKNFKTKVDAGANSAITQFFFNVDSYFKFIE
ECERLNISIPIVPGIMPIYNIKQLSRFAQTCGAEIPRWLKYKLESYGDDIESLREFGIDF
ISELCETLQQFGVESFHFYTLNECGIVSKVLKNISD
>R6Q516|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. CAG:386|TrEMBL
MNIADFLNKEGQKRGFSFEVLPPLKGNGTAALFRTIDSLKEFDPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTIAIAGAIQNKYDIPVIPHIICSGASKEDIEYELLDLQFLGISN
VLVLRGDKAKEDRQFTPTLNGHAHATDLLKQISQFNEGFFIDGTPIKYPGEKFYCGVACY
PEKHEEAPNLEQDLLHLKEKQDLGASYAVTQLFYDNQKFYDFVERARKMGITMPIIPAMK
PFAKLSQLTMVPKTFHCDIPEELAQEVQKCKTDDDAKALGIEWTTTQVKDLFEHGYSHVH
FFTVSAVESVKQIAKILF
>A0A255TZT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. P5-64|TrEMBL
MKVVELINIHKDKKNFSFEVLPPLKGTGTGKLFATIDKLKEFDPLYINITTHHSEYVYRK
LDNGQFERMRIRRRPGTVAIAAAIQQKYGIPVIPHVICSGATIEHIEYELLDLQFLGIEN
LLLLRGDKAKDDRVFTPVAGGHAHTTDLIEQVNRFNSGYFADGSAIKVPGTPFGYGVACY
PEKHDEAPNMEMDMGYLKMKQDMGAEYAVTQLFYDNSKYFDYVDKARAMGITIPIIPGIK
PLAKLSQLTVVPKTFHCDLPQELAAEVKRCKTDDDAKQLGIEWATHQCQELYAHGINNIH
FYTVSAVNSVAEVTRRLI
>R5EB75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:590|TrEMBL
MIKDIYQPGKTVFSFEVFPPKRNDDIYDIYKTLDQLKTLNPDFISVTYGAGGSNSKKTAT
IASYIQNICEIEAIAHLTAVAMNSEFLIDFLDKLQQKGVCNVLALRGDRPRDMSDEDYSN
RTFLHASDIIQIIHKHSDLCVAAACYPEIHPESETRESDLHYLKEKVDSGVNFLITQMFF
DNERFYEFRELARKSGINVPISTGIMPITAAKQLGTSVSLSGTSVPTKLSSMVAKYADNP
DDLRKAGIEYAVEQINDLIENDVDGIHIYTMNKAATAIDIMKQVHRK
>A0A3S3SS87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sufflavum|TrEMBL
MKVTQHIANAKGKPLFSFEIVPPQKGSNINELYVNIDPLMEFKPPFIDVTTSREEYVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGIDAIPHVLCGGFTKEETEYLLVDCQYLNIDNL
VALRGDPMKGEKYFEPTVGGNHYAVDLVKQIKAMNGGRFLHGELPIANAPDFCVGVAGYP
EKHIEAPSLEADLKRLKEKVDAGADYIVTQMFFDNQRYFKFVEAARAIGITVPIIPGIKP
VAVKRHLQLLPQVFWLDMPESLISSIENAKDNAAVRQIGVEFAVQQSKELIEFGVPCVHY
YSMGKSDNIYNIASQVF
>A0A2P2KPK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophora mucronata|TrEMBL
MKVIEKIKAAAAVGGEANGGTGDVGGAQNVVFSFEFFPPRTEEAVDNMFEKMERMVAHNP
AFCDITWGAGGSTADLTLEIANRMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQN
VLALRGDPPRGQDKFVQIEGGFACALDLVRHIRSRYGGYFGITVAGYPEAHPDMIGDNGV
ATLENYHKDLVYLKEKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINN
YKGFKRMTGFCKTKIPSEITAALDPIKENEEAVRSYGVHLATEMCRKILAHGIRTLHLYT
LNMERSALEILMNLSLIEESRIKRPLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRTIGW
DQYPHGRWGDSRNPSYGALNDYQFMRPRARDKKLQEEWGAPLKSVEDICEKFKSLCLGRL
KSSPWSELEGLQPETRIINENLGRINLKGFLTINSQPAVNGEKSDSAAVGWGGPGGYVYQ
KAYLEFFCSKDKLDALVDKCRAFPYITYMAVSKGDSWISNVGLNDVNAVTWGVFPGKEII
QPTIVDPASFHAWKDEAFEIWSRGWASMYPEGDPSRNLLEEMQISYFLVSLVDNDYVHGD
IFAVFADL
>A0A4R4TYV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. KC606|TrEMBL
MALGLPSVLPNPQPAIGELIRRDAPTFSFEFFPPKTPKGDQLLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVEVTERIATETTLLPMAHLTAVDHSVAELRNVIGRLAGAGVRNVLAVR
GDPPGDPGGEWVRHPEGVLYAEELVRLVRDAGDFSVGVAAFPYKHPRSSDIASDVAHFVR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFARVAHDPEAVRRLGVEQASEMCAKLLDEGVPGIHFITLNRSTATREVWRSLQ
AGVRV
>A0A7V6JVH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MAVFTPLRRWQPAFRPFSRQSAGKRLLALTERIIKGPLFGCRMCGNCLLQETAFICHMAC
PKGIRNGPCGGVNNGYCYVDPSRRCAWNLIYERSRGMHREHKLLEVLPPVDWEKAGTETW
GEVVRTARETGIRNIFVPSRRKGQTMGSVLEESIFKPIRQPDWWKGDSEYHPPAVSGPQS
SLETELRSGRFVITAEVTPPLTASTVKLREKILMVMPYVSAVNFTDGSSAVPRMSGAACS
AVAASLGADPVMQISARDNNRNSLQSMAIGANAQGVYNILCLSGDSPRVGRAPWSSMNII
DVDSVQMLWILRRMRDEGIYLDGREIKNRPKLFLGAAAAPFALDPAMQAIRIRKKVNAGA
QFIQTNLVFDPDRLDPWLEQLEKENLLDKVFILVGISPIKSLSVARYLNENIPGVTVPER
VMQRLADAGDRFTGESIDITVETLLKLKSKKGISGVHIMPLGWEDAIPLIIKQAAYETTD
FKGAGQGRQS
>A0A6N9J8F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium|TrEMBL
MKISEKLKSPVFSFEFFPPKDEAGFQSLFETIEKLKPADPAFVSVTYGAGGSTRSKTVDL
VGKIKNEIGIESMAHLTCVGHKKKEIVSVLESLHACGIENILALRGDPPRGEEKFVKPEG
GFGYANELVSFIKSKFSFCVGAACYPEGHVECPDLQKDLDNLKRKVDSGVDFLITQLFFD
NQHYFEFIKRAEKEGIHIPIIPGIMPILNLKQSQRFTQMCGASLSDSLLSKFEGFEDDPE
KVREIGINHAFEQCRELLSSGAPGIHFYTLNRSRATLAILEKLRG
>A0A2H9MXV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon CG15_BIG_FIL_POST_REV_8_21_14_020_33_23|TrEMBL
MTIIYEVNPPKIPDNETPDDEIKSSIEKLMQRVSDISALCDGIHVTDSVLGTKRVSALTV
GRLLKKKHPDLQITISMRVRDKDMSLIKQLTQESIELKLDGILILKGDPSKENPTDSGLI
PSQVVKELNELGYGNKMNFFLSLPSNPNFEKIQKKIAASPKGFMTQVIHSAEQVQRISNK
LKPKGLRIIPCVLLPSEKNNNSAKFLELDWSNYKENPSNFIKQIHNIAGDVLVTSPNDFT
FAKETLKKI
>A0A7V9K9E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacteraceae bacterium|TrEMBL
MSFDLRERVGSQVLIGDGAMGTLLAERGVGFGHPYARANVTHPEMVAGIHEEYIRAGAGV
IETNTFSANRFKLEVHELEDRVREVNEAGARLARKAADNTKTAEGDKALVLGAIGPLGRP
LCPVGPVTENEARAVFLEQAEALLEGGADALVLETFTDLVELRLAHEAVRSLGVPIVAYK
TFVEDGETLSEGLPGRAAREISGLGVDLSGANCTVGPQRMVGIIEGMSIEVGPVAAFPNP
GLPQLVDGKVRFRRDVDHFALYGRKLAEAGARLIGGCCGTTPEHVKALAEVLRDFRPEAS
PNRGVRVRTVEEEGPEVVLDGPSTELAEKLRSGFAVAVEVDLPRGNDITKVVEAAKRLKE
RGVDAIDISDGARARLRMHPVAAAKIVQDEAGIEVVAHISCRDRNIIGLQSDFLGAAALG
VKNILAVTGDPTQIGDYPEATGVFDTDSTGLVHILSKMNRGEDLAGNSIGGPAGFLIGSA
FNPTAEDLDGEIEKLRRKIGAGAHAFWTQPVFEIGALQIALERMGDLEVSLLLGLMPLRS
ARQAEFLHHEVPGVNIPKHVRERLADLSPEDAPKYGVEVAQNLLAKAQPLVNGAYIMPPA
SAPDLAGDVLEGITPQASGVRNN
>A0A838KZH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacteraceae bacterium|TrEMBL
MEESVVEHVPKDIALTVTASPGKGTWATVELAERLAGHGFGVAPHLSARLIRDRLELGEI
LQRLRDAGIRKAFVVAGDVDEPAGEFEGATGLLEAISEIGHDLDEVGITGYPESHPKISD
EMTIQAMYEKAPYATYIISQICFDPEVTSEWARRVWLRGVKLPIRVGMPGYVNRQKLVRI
SAGIGLGESARFLHRQRNWLLKLFMPGGYSPDRLIEGLKPGFADPESNIQGLHIYTFNEL
EQTEAWRREMLQRAEPSA
>A0A3P6TVL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cylicostephanus goldi|TrEMBL
MKQRVDFIFLPGYPLGHPEAPSYKADLLYLKSKVDAGAQFIITQLFFEAEVFEQFVRDCR
EMGITVPIIPGIMPIMGYDSIRRIAKLSQLTIPEKVLLDLEPIKHDDDAVMKYGTVKAIE
MCRRILSSGSAPSIHLYTMNREGACR
>A0A8H4LBK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium albosuccineum|TrEMBL
MDKITDRIAALPADGSYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVKYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKIQAGVDFIMTQLFFDIKAYEHFENTLRDHPSGAFKTIPIIPGLMPIQSYQMIKRT
TKLSHAKVPEEILSRLNSVKGDDERVKMVGVDIVSELVEKVKDIKSKTPGPKGFHFYTLN
LEKAVSFILERTNLIPEPPEDEEAVVVDDAIPIPIPALQVNGSTNLRSGSHSRSRQSRRH
SSVGSDPHNRVIVGDRPATHPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWD
DFPNGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGNPKTRQDINDLFVKHIQGELSAI
PWSEEELLAESSTIQPHLLQLNRKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFV
EFFIPTTEWNTLKEKLVSSEYCDSVCFYAGNGHGDFVSSDNGHVNGGAAPGPSTNAVTWG
VFPGKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDEYWLVNLIH
HDFVEKDALWQVLTS
>A0A252EH81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter senegalensis|TrEMBL
MSLSRLSVELIPRSTEALLDDVASVKALFPATDTLNVPDLMRFPLRSWDAAALIRPHFAR
VVPHIRAIDIAPDAPLPGADQPGLEEVLVVHGDPPADLSHRTYPNSTESIIRRYKKEAPH
LRIYAAFDPYRRAPWQELEDVARKKEAGAEGFFTQPVFDLKLFDLCREWLRDETVFWGLS
PVIGPRSRSYWETTNHVVFPKDFEPTLEANIQFAQTVLRHLSQEKGRAYLMPLRVKLDQY
LPPLIEALA
>A0A3D9D1J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epilithonimonas hispanica|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFKPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEPSVGGHKYASDLVKQIHDLGIGEYLHGKIESDIDNSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKFFDFVKQAREIGIDVPIIPGIK
PIATKTHLQMLPQVFKIDLPEALINEVLKCKTNNDVREVGIEWAINQSKELLDFGIPVLH
FYSMGKSDNILKIGREVF
>A0A1X1MHW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. KB5|TrEMBL
MREPTAGHERPVRGFEMICEIEPPTRPDLTHARHQIGVLSPVTDAFLIPDNHIGRATVSS
IAVAHEVATMGGRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVHGDKPTAGNRTGDL
TVRAMMDEARAASEDPVFADMPAFRVGAAAGLRPLPTWKRAADFLFVQISYSVDALLRWR
DAHPVELPIYAGVMVLASAGMARRLAAAIPDIDIPDDLVQAVERDQAAGVEAACDQVLRL
RDSGAFAGVHLVPVSRYRQVATRLEDLL
>A0A2E9Z5C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium|TrEMBL
MKIQEILQEVRPAFSFEFFPPKDDDGFDQLFQTIDRLKSWNPAFVSVTYGAGGSTRSKTI
DLVGRIKNEIGLESMAHLTCVGHSSDEICSVLKSLQEQGIDNVLALRGDPPQGETNFVKP
ENGFGFASELVGFTRDKFPFCIGVAGYPEGHPECPDHRQGLEHVKNKIIAGGSFIVTQLF
FDNKVYFDFVKNLKDIEVDVPVIPGIMPILNLKQIKRFTKMCGATVPADLLARLESVQDD
PEAVREIGIDHATAQCENLLSQGAPGIHFYTLNRSRATLSVLERLKSISIGS
>A0A5F0UAZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. P14|TrEMBL
MKVIDLINGSKTTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQNTDLYHEHATDLQEQVNNFNKGIAVDGSTFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVERCRAEGIDVPIIPGIKPV
VFKNQLTVLPKIFRSDIPEPFAAELRKCKNDDEVKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMATDSVYKVAKEVY
>A0A3N5E1R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVIDHINNAKSTLFSFELLPPLKGSTLQTIFDTIDPLVEFNPAYINVTYHREEVVYRPL
PNGSLIPTVLRRRPGTVGIAAAIQHKYKVDIVPHIICGGFTQLETEDALIDLDFLGIHNI
LVVRGDADKIVGKFEAKSGGHRYAVDLVKQVIAMNNGIYQDESLEKPNPTNYCVGVAGYP
EKHAEAPNSISDLQRLKEKVDAGADYVVTQLFFDNSKFFEFEQKCREIGIKVPIIPGIKP
ISIKEHLSILPKIFNVHLPHELVKGMEKCKDNKAVKELGVEWAITQAKELKANGVPSIHF
YTMGKSDNIAKIAKYIF
>A0A3C1A9H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MHVAEILSKSNKTLFSFEILPPLKGGSFNDIYKSIEPLLEFKPAYINVTYHQEEVVYKDR
GNGLLEKKVVRKRPGTVGIAAALQYTCNIQVVPHMICGGFTREETENALIDLNFLGINNV
LVVRGDPDRSQKTFIPEPDGHIHSLDLVKQIVDLNHGKYLEEDLQNSTPTNFCIGVAGYP
EKHPEAPNKASDLRYLKMKIEAGASYIVTQMFFDNRKYFEFVNDCHEMGINVPIIPGLKP
VATCQHLYLLPKTFGIDLPDDLAKELEKCKTNQEARNLGIEWTIQQTKEIIAAHVPAVHF
YTMGRSDNIYQIAKACF
>A0A136K4G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium OLB17|TrEMBL
MIMKKFRDLISGEGVYVFDGAVGTPLYDKGIYINRSYDELNLTQPELVKEVHDEYVAAGA
DIIETNTFGATRPKLQPYGLESKLHEINVAAARIAREAAGERAFVAGAIGPLGLRIEPFG
PTSFDEAKGFYLEQVNGLLEGGVDLFILETFSELEIIEQAIRAVREASDLPIVAQMTIQM
DGKTAFGSTPELIATRLDELGADVIGLNCGMGPNHILNALEKMRAVTDKDLSAQPNAGLP
RDVQGRQFYMGSPEYMATFAKRFVSAGTRFIGGCCGTTPTHIKLIADAVRSISPRQAISE
ARKQIVAVAEIKPPDIQVVPREDRSRWSGKIARGEFVTSVEVLPPKGCDAAKTLESIHLL
HECGVDGVNIPDGPRAQTRMSALATAVLVQEKVGIEPVLHYCCRDRNLLGMMSDLLGAAA
LGLHNLLLITGDPPKMGPYPDATAVFDIDSIGLTNMANKLNHGLDLGNNPIGRPTEFSIG
VGVNPGAVNLDEEIRRFEWKVEAGAEYAITQPVFDTEQLRHFLDRISHVRVPIVAGIWPL
ITYRNAEFMHNEVPGVNVTPQILERMRIASDKSKEHGREEGIAIARESLLEVRDAIQGVQ
VSAPFGNVKYALQVFEALDGFRTA
>A0A8E0S8W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. ANT_WA51|TrEMBL
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTRAKEFIS
VHHERTEPGLDEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMAHAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>A0A524G4J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MNREFFNLFSTRLKQTLDAGTFAITGEISPPRGADSNLVIEGTKLIADYCDAINITDNVS
GIPTMSSTACARLVLETGAEPIMQISTRDRNRISVESELYGAYALGIRNVLFITGDRTIL
GAHSNAKMVFDIDSIQALQLSSHLMRGTDFDGGELEGTPKFFMGSTFNPYADSIEMELQR
TEMKRDAGAEFFQTQAIFDTDRFEFFMESARDLKLKVLAGVIPLRGPLMSRFMNENVPGI
NIPEKYIKRLESAGKGLKEDEARAAMLEEGLLIASETIKTIRKIRGIHGLHLMSIGREES
IPELIKRAGLSPRIRKV
>A0A8C6UVP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neogobius melanostomus|TrEMBL
MVNQVQRGDGTLSSRSDSSAASASGGDSSKESSRCSTPVLDADRTDRLRYKMRRRMESGD
HWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPSGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQSKDNISRHLSKAKHLGLKNIMALRGDPVGSDWEEEEEGFNYAVD
LVKHIRSEFDDYFDICVAGYPTGHPEAHSYKEDLIYLKEKVAAGADFVITQLFFRAETFL
KFEEDCRPSGSPCVCVQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIHQAL
EMCRVLLDSGRVPGLHFYTLNREVATMEVLRQLGMWQEDPRRPMPWAVSAHPKRKVEDVR
PIFWGSRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSVFEVFTCYIAA
QPNRKGHKVMCLPWNDEPLAPETNMLKDELEKVNTRGVLTINSQPNINGKPSTDPIVGWG
PPGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTW
GIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNL
VDNDFPLDSCLWQFLFCFFLCFFIQNRYEP
>A0A828XBA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus BAG4X12-1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLMHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7C8IV51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylaria multiplex|TrEMBL
MHINDMVADAERTGEPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDITXFFGLETC
MHLTCTDMGEEKVNEALQKAYKAGCTNILALRGDPPREKEKWEATDGGFQYARDLVAHIR
RKYGNHFAIGVAGYPEGCDDNKDEESLLDHLKEKVDMGGTFIVTQMFYDADNFIRWVGKV
RERGITVPIIPGIMPIATYASFLRRAHHMNCKIPEKWMAALEPIKNDDSAVREVGKVLVA
ELCRQIKSAGIVHLHFYTMNLAQATRMVLEELDWLPSSQRPRQQPLPWKQSLGFGRREED
VRPIFWRNRNKSYISRTQEWDEFPNGRWGDSRSPAFGELDAYGIGLTGSNESNRKKWGEP
QSISDIANLFTRYLEKELDSLPWSEAPLSGEAVSIKDDLIKLNKRGFITINSQPAIDGVK
STHPIYGWGPPNGFVYQKAYLELFVHPELYGEVIRRIEGRDALSYYAVNQAGTFTTNAPS
EGPNAVTWGVFPGKEIVQPTIVESVSFLAWKDEAYRLGNDWARCHEANSPSRVLIEGIMK
EWYLINIVNNDFHDTNAVFELFDGLEVKDLDTPASSAPHTNGTNGAHKEVNGIAASN
>A0A523XP97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Heimdallarchaeota archaeon|TrEMBL
MAKRPAYSNLCKAIEAGHFVFTGELEPKKILNLDEIIHSAKEMKKTGRIVAANVTDGPQG
DAYMSSMIPSYLVQEKANIEAVWQVTVRDRNRVALFGDVIAGAVIGLKNILTLTGDHTAL
GDHKKGRPVYDIDSTQFAEMLSMMIDEGTDYEGNELEGGKIEMNFGCVANPNSDPREPEI
LKVGRKVKLGVDFIQTQTAFEIDQAKEFLKDLEQ
>A0A1G1AEV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium RIFOXYA12_FULL_48_11|TrEMBL
MQIRNILSRNNRCFSFEFFPPRDTEASTQLFQSINDLIPLNPAYVSVTYGALGSTRELTH
DLVVRINRETNLTVVSHLTCVGSGKDEIYKILEKYQGSGIENIMALRGDPPEGQKSFIKP
ENGFSHAAQLVAYIKKHFPKMGIGVAGYPEGHPETPNRLKELDYLKMKVDEGADYICTQL
FYDNRDFFDFCERCDIAGIHVPVLAGIMPVTSRKGMMRLAEKTLCVRYPARLMKAIARAS
SDEYVEKVGIQWATEQVRDLIDADVKGVHFYTFNKARATRGIYESLGVTSSAQLTK
>A0A1F9PQ62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula sp. RIFOXYB2_FULL_45_6|TrEMBL
MMLRKKLTQGEFAVLVELNIPKGVDISELVTHVRHLKSRIDAVVIPDMDGGVMRMSALGG
GAVIRREGFEPVIHIYGRDRNRMAIQGDVLAAQALGIQNLIVVQGDAMANSDHPAAKTVD
DLNELDLLSMVQSLQKGVDLAGFDLKGKPAFFTGCQVQPIRDDKHLSEEYEKAKEKVAAG
AQFIVVPPVFDIPAYTQILNKLKSLKVPVIATVFMLKNVGMARYISINDPGSGLSDELIG
RIRKAKDREMECVHIAAEMIQSLKGVAQGVKISAVGWEDRLPAILDCAGL
>A0A2E3H1Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudooceanicola sp|TrEMBL
MTVPSVSFEFFPPQNLGASFRLWDTVQVLSPLAPRFVSVTYGAGGTTRDLTRDAVATLHK
NAGLNVAAHLTCVNATREETLAIADSFAEAGVTEIVALRGDPPKGTGKFAPHPEGFAHSV
ELIEALAVKDKFTIRVGAYPERHPDAADEAADIDYLKRKLDAGASEAITQFFFETETFLR
FRDRCAAAGITAPIVPGILPIENWKGMRKFAAGCGANIPAWLDEAFDKAARDDRQDLLAT
ALCTEMCTDLLSEGVESLHFYTLNRPELTRDVCHALGVTPDVRLENVA
>A0A428YBQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes sp. ATCC 53533|TrEMBL
MSHGLPSRLPTSPAIGELIRRPGPTFSFEFMPPKSREGEQLLWQTIRELETLRPDFVSIT
YGAGGTTRDTTVAVTERVATETTLLPMAHLTAVGHSVAELRNVIGRLAGAGIRNVLAVRG
DPPGDPMGEWVRHPDGVLYAEDLVRLLREVGDFSVGVAAFPYKHPRSADVESDTRHFISK
CRAGADFAITQMFFEADEYLQLRDRVAAAGCDTPIVPGVMPVLRMATIARAAQLSGAPFP
PGLLARFERIADDAAGVRALGIDLCSEMCQRLIDEGVPGIHFITMNRSTATREVWQNLAA
NVPA
>A0A1S9NW36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces antibioticus|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFYAPKTPQGEKSLWNALRRVEAVAPDFVSV
TYGAGGSTRATTVRETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSTAWDTDVEHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPKLSNAHF
PGELKERILTAKEDPATVRSMGIEFATEFCARLLAEGVPGLHFITLNSSTATLEIYENLG
LHHPPRV
>A0A519UQH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKITDHIAQSGGKTLFSFELLPPTKGKSIHSIYDAIDPLMEFKPPFIDVTYHREDYIYKQ
HESGLLEKISYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARQADTNFIPTAGGHNYASDLLQQVVNMNQGKYLHEDHEAFKTDFCIGVAGYP
EKHFEAPNLKSDFKFLKKKVDKGANFIVTQMFYDNQKYIEFVKKCREHEIHVPIIPGLKP
ITSSKQLVSLPKIFHIDIPEELSEAIQACKSEAEVKEVGIEHMIAQCQELIKLGAPVLHF
YTMSNPNPTKRIAAALF
>A0A7S3Z175|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lotharella globosa|TrEMBL
MNGHLQFSEKKNKRDLSDIKGGTSTPRSGPSEKIINKINRAVNERRTFYSFEFFPPKTEA
GVMNLYNRIDRMVAKYEPMFVDVTWGAGGSTAKLTLEISSNVQNYCATDVLMHLTCTNMP
RDSVKDALDKAKEAGIRNILALRGDPPHGQDTWEKCDKGFEHALDLVKFIREEYGEYFGI
AVAGYPEGHISSPNLEEDIKHLKLKVDAGADFIMTQLFYDVDLYIDFVKRCRQAEITVPI
LPGLMPINSYNAFKRMIAYTKATVPKEIIAAIEPIKNNDAMVKAFGIELAKKMSQKILRT
GLTPGLHFYTLNLEKSVTKILGGLGLARLPSKGVRPLPWKQSCATRRRNEDVRPIFWANR
PYSYLSRTISWDEFPNGRWGNSTSPAYGELYDYHLMGLKSSSVRDRLRMWGGEVQSEQDV
FDKFADYIEGKIARLPWCETGIMLETLPLKQRLMAINKTGFLTINSQPRVNGARSDDEVG
VVLCWVLGIWAGRDRCPRTSQSMVIRWWGGGI
>A0A7H9K1I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEL
>A0A7S3Z0N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lotharella globosa|TrEMBL
MNGHLQFSEKKNKRDLSDIKGGTSTPRSGPSEKIINKINRAVNERRTFYSFEFFPPKTEA
GVMNLYNRIDRMVAKYEPMFVDVTWGAGGSTAKLTLEISSNVQNYCATDVLMHLTCTNMP
RDSVKDALDKAKEAGIRNILALRGDPPHGQDTWEKCDKGFEHALDLVKFIREEYGEYFGI
AVAGYPEGHISSPNLEEDIKHLKLKVDAGADFIMTQLFYDVDLYIDFVKRCRQAEITVPI
LPGLMPINSYNAFKRMIAYTKATVPKEIIAAIEPIKNNDAMVKAFGIELAKKMSQKILRT
GLTPGLHFYTLNLEKSVTKILGGLGLARLPSKGVRPLPWKQSCATRRRNEDVRPIFWANR
PYSYLSRTISWDEFPNGRWGNSTSPAYGELYDYHLMGLKSSSVRDRLRMWGGEVQSEQDV
FDKFADYIEGKIARLPWCETGIMLETLPLKQRLMAINKTGFLTINSQPRVNGARSDDEVV
GWGDPDGYVYQKAYIEFFASPERIKSLKALASRKEYKTLSYHAVNAKGDQFSNYTDKNAV
NAVTWGVFPGREVLQPTVVDMDSFRVWKDEAFALWISQWRSIYSSGSASWEIIQKIHDTY
GSPITPALFL
>A0A7C6AJB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MNYKAWLQLLQERIVLADGAMGTMLYNKGVYLNLCFDEVNLNNPDLVKSIHREYIQAGAE
IIETNTFGANRFKLKKHGLEDKVSEINRGGALIAKEEAKKGVWVAGSIGPLGVKIEPWGP
TSVEEAEEAFREQVRGLLAGGVDLFILETFSDINEIHQAIKAVQSEAPDYLVVAQMTIEE
DGTSLYGTTPEVFTRKLEEWGAHVIGVNCSVGPAAMLECIERMAKVTTNPLSAMPNAGIP
RNVEGRNIYLCSPEYLAEYARRFILNGVRLVGGCCGTTPAHIRAIRNAIKALQPTKRSVV
IISEEVELPAVQKTKPMSEKSALGKKLSQGQFVVSVEVVPPRGWNASAAVEVSRQLKEKG
VDCVNIPDGPRASCRMSSIALAFLLQAQAGIEVILHYTCRDRNLLGIQSDLLGVYAHGIR
NLLLITGDPPKLGDYPDATAVFDVDSIGLTNVVKFLNQGLDVGQRRLPEPTGFLIGVGAN
PGAINLDYEISRFRWKVEAGAEFAITQPVFDIQLLEDFLSRIEGYRVPILAGVWPLASLR
NAEFMHNEVPGARVPDEIMERMRRAQEVSPERAREEGIAIAQETILRVKDMVQGIQVSPP
LGKYETALKVLEVL
>A0A7L0SG33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Podilymbus podiceps|TrEMBL
MVNETQHTCSTSSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6F9ZG10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidaceae bacterium|TrEMBL
MRVVDLIKSTDKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
DNGLFQRTRLRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHEPTFVPESNGYNHALELEMQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHDESPNLEQDIYWLKKKIETGAEYAVTQMFFDNRKYFKFVERIRKEGINVPIIPGIKP
FSKLSQLNIIPKTFKIDLPQELAVEAMKCQTDEETAALGVEWCIHQCRELIAHGVPSIHF
YTVSAVDSVKKVAKAIY
>A0A2R6N6F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon SW_8_66_22|TrEMBL
MAQQSLSRSDGADALLRDARFELMPFDSFDDELTYLPDGATIAITTSPQLGIERTVERAE
QAAADGYEPVPHIAARYVRDGDHLEEIARRLTEAGVTEIFVPGGDREEPVGEFESAYQLL
VALDETEYSFEEVGITGYPEGHEFLDEQTLRTEMDKKAPYATFIVTQLCYNPEAVIEWIE
KIRGRGVDLPVEVGIPGVMKYSRLLQISRKVGVGDSVKFLRKTTGVVDFVRQIVGSRGTY
KPDELVDGLGPYADDEEYKISGIHIYTFNQTTDTEDWRRGRLQG
>A0A1G8SLY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas gudaonensis|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGKFAVTSEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGAHCHMSSVGVCSLLTRVGYATILQMSCRDRNRIAMQGEILGAAAMGAC
NLLCLTGDGVQAGDHPQAKPVFDLDSMSLLEIARGMRDESRFQSGRRIELPPRIFLGAAE
NPFVPPQAWRPHRVAKKVAAGAQFIQMQYCFDVPQLRDFMSGLGDLGLLEGPERVFVLPG
IGPLASARSARWIRDHVPGVHIPDAVIARLEGARDQKEEGKRLCMELLHQIREIPGVSGA
HIMAYRQEHSVAEIIEATGVLEGRVPWYPGRDDPSERNPESPEASPEAEPLQG
>A0A259JBC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azorhizobium sp. 39-67-5|TrEMBL
TRKLIAAAVAAEQVTDLVDRGVGDIHFYTLNRADLVYAICHLLGLRPGAAETPAQRLAG
>J7VJ10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia Ab55555|TrEMBL
MTVISFEFYPPKTDEQRSQLDRAAAKLKDYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RTEHGDAFHIEVGAYPETHPQATDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWIGRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A503L7R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-4-16|TrEMBL
MTVRQLDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFRTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKDRQPWKRERRRDDQLVADRLDHLLHDEITETQVDMVK
TAH
>A0A2H0QUX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium CG11_big_fil_rev_8_21_14_0_20_39_49|TrEMBL
MLLSKKLDQIKDSISNPPPKVSFEFFPPRTDSGVEKLKENISLLEKLSPAYCSVTYGAGG
STQEKTYEIVKYIKENTTIKPAAHLTCVNAIRDEINNVAKSYLDIGVNKIVALRGDVPGG
TGMYEPSVAGYAYADSLVKGLLELGDFDISVAAYPEVHPQATDAAFDLKHLKRKIDAGAK
RAITQYCFDTDKVLRFIDKARAIGIDAPIVPGVVLMNGFEQLISFSKRCGANIPEWMFDI
FSGADQNPEICDMASVAVAAEQCRLLMQEGINEFHFYTLNRANPTIAVCRLLGVK
>A0A377LQ77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MKWSKPSGALSIGLSSLKPKFVSVTYGANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDA
TGDELRAIAQDYWNNGIRHIVALRGDLPPGSGKPEMYAADLVALLKDVADFDISVAAYPE
VHPEAKSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPV
SNFKQAKKFADMTNVRIPLWMSKMYEGLDDDPETRKLVGANIAMDMVKF
>A0A4U6BB21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiaceae bacterium LC148|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLSTVRTMRDEAKFLSGRKLTTPPHVFLGAA
INPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGFHEKCFILVGVG
PLASAKTARWIRSNVPGIHIPDSVIARLEGAQDQKREGKQLCIDIINEVKEIEGVSGIHV
MAYRQEEYVAEIVHESGVLKGRRPWKREANPTDALVAERLEQLREGREQNQEQLADIAAH
KPH
>A0A3A8IT30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus sp. CA049B|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTVEELAPLEPGFVSVTYGAGGSTRDRTV
DLVTHIKRQTGIEAMAHLTCVGHTRDELRDVLRRLDAAGIENVLLLRGDPPQGQTTFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVGALKGRS
>R6VPT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:380|TrEMBL
MKIADICKKKKSLSFEIFPPKRTEDLENIDETLSVLCECDPDFISVTFGAGGSSNCNRTI
ELAKKIKNEYHVEPVVHLTCLHYNKSEIDEFARILTQEGIQNVLALRGDRNPDIPEKDDF
KHASDLIRYLKPKSDFCFLGACYPECHPESDGKISEMKHLKAKVDAGAEVLLSQLFFDNE
QFFRFVEDCRIAGIGVPVIPGIMPVINARQIKRMVTMCGASFPERFQRIIHKYEDNKEAL
FDAGMSYALSQIIDLLVSDIDGIHLYTMNNPLVARKICDGIRHII
>A0A484TE33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|plant metagenome|TrEMBL
MEVSAKDIPALTAVAPRLPPASTISIPYLAGEGNAARLAAARAVRELGFEPMPHISARRV
ASLAELQAFVARAAAEAGVERCFVIAGDPSTPKGPFPDSFSLIDTGVFERAGIKALGVGG
HPEGHPVMSVADRWEVLERKCRGIEERGMAPSIVTQFVFDADVVLTWLEALRARGIAHPV
RVGVPGPAGVAVLARYAAMCGVGACASMLAKYGISIGKLLGTAGPDRFVDRLAAGRTPAH
GTVSLHFFPFGGIAQSVGWIEQYRATRKQNTR
>A0A6J4K9H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Gemmatimonadetes bacterium|TrEMBL
MRDFRRLLADGRPHLFDGAMGTMLYAKGVYINRCYDELSLTQPDLVRDIHRAYVKAGAEI
LETNTYGANRPKLARHGLDDRVREMNVAAAQLARAAAGERVYVAGAIGPLGLRIEPYGPT
AREEARGFFREQAEALVEGGVDLFVLETFADLEEIHQAILGVREASELPIVAQMVIREDG
TTAFGSDVALLAERLGEWGAEVVGLNCSVGPSAMLSAADRLMASTSRPVVMQPNAGLPRQ
VDGRTMYMASPEYMASYAARMIRKGVRLIGGCCGTTPEHVAAMAGAVRMLSPAAEPRVVV
SEPDAEGAVPREPVPLPERSAWGRKLAAGEFLTTVEIVPPRGSNPEAMLDGVRLLKQAGV
DGVNVPDGPRAQSRMGALATAILIQQRVGIEAVVHYCCRDRNLLGMLSDLLGAQALGLRN
LLLITGDPPKMGPFPDATAVFDIDAIGLTNLVSRLNRGLDPGGNALGEPTSFVVGVGVNP
GAEDFEHEMRRFYWKVEAGAEYAITQPVFDLRQLETFVERIEKDGLKIPLIAGIWPLVSA
RNAEFLANEVPGVVVSDEVMARMRRASAESKERGVEEGTQIAQEMLAAALPMIQGVQVSA
PFGKVPLALRVFDAIPGWAAHEAAVAGAA
>A0A7Z7VTI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus agnetis|TrEMBL
MSRLLNTLKDNILVADGAMGTILYSEGLDTCPEAYNLTHPEKVEHIHRSYIQAGADIIQT
NTYGANFEKLKAFGLEHKVRDIHEAAVAIAKRAAKEDTFILGTVGGFRGIKQGDFSLPAI
QYHTEIQVDSLVQGGVDGLLFETYYDLDELLTVIKATRKKYNIPIIAQLTASNTNYLRDG
TVINDALEQVIQAGANIVGLNCHHGPHHMKNTFSHIALPSHAYLSCYPNASLLDIENNNF
KYSNNATYFGEVAEQLIQEGVRIIGGCCGTTPEHIHHIKTSVQGLKPIKHKKVIPIHKKQ
ESTQHPSSKFNLKERVTRQPTIIVELDTPKHLDTERFFKNIEALDRANIDAVTLADNSLA
TVRISNVAAASLIKQKYHIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNEGINTDGDALKRRTNFNIAGGFDPHVRNIDAAVRK
LETKIESGMHYFITQPVFTKEKIVEIYEATKHLNVPLFIGIMPITSYNNALFLHNEVPGI
KMTDDVLARFKAVAGDKAATYELSISICKSLIDTVHQYFNGLYLITPFERVDYSLELAAY
SKSITSTNQEVIL
>A0A662LMC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MSFQKQLSSGEFVVLAEMDTPKGVDISELITNARRIKGRVDAVVIPDMGDGMMRMSALGG
GVLMHQQGIEAIIHVCCRDRNRLALQAELLSAHVLGIQNVVVARGEEMAYGDHFDAKSVN
DLDEIGLLQAIRSLQEGVDLAGIELKGSPIFTVGCTIEPYVDDKALDRELELAQKKVEAG
AQFIITPPVFDMDLFASFVEKAKPLGVPLIPTVFLLKSVGIARYMATTLPAYHISEELIS
RIRKASNRELECIRIAGEMVANLKQLAQGVHIVTLGWEYQLPSILDYSGL
>A0A3A6J907|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. AF38-1|TrEMBL
MNILESLKDKLLVADGAFGTCYVGMYGEQGTVAPELANIRHPERVLEIHKEYVKAGAGLI
RTNTFAANTASLDADMDYVISNVRAAVKLAKQAAEEDVEAADCVRTSDAVVTEADESGTY
RKKVSVAGDIGPIPADAGLTLNERVSQYKLLGEAMQDMGVDIIWFETFPEFNVLEPVVKH
LKARKNTPVMVSFCVNQFGYSNCGFSARALLSQVAGNQDVDCVGFNCGVGPYHMLQLLKK
LDIDCGKPVSVMPNAGYPKFTQSRLVFNDNKEGFIDKIQDIAALGADIIGGCCGTNPEYI
HQIMEWVKTGDIAKAAKVHVEKVQADSAVKDNFLKGRLERGGAATKNADGHKHKLIAVEL
APPVDVNDQKLLDAAHILKQSHVDVVTFPDSPSGRTRADSILMAEKVHKETGLRVMPHLC
CRDKNAIAIRGSVLGSQLNGIKDFLVITGDPVPVMFRQTTRSVFNFDSVGMMKLLQSMNE
EVFSGDKITYGGAINQNRLNTKFEIDRIKRKMEAGAEFFLTQPVFSREQAQILRDMKAET
GATILVGIMPLVSRRNALFMKNEMSGIEIPDEIIERYSENATRQEGEECGIQIARDILEY
TSDFADGYYFSFPFNRVHMLAHIVD
>A0A3A5JF17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halococcus sp. IIIV-5B|TrEMBL
MAAKTTSDTVDGVSGLLADPRFELMPFDSFDDQLTYLPDGAEVAITTSPSLGVDATVEAA
ENAATQGYEPVPHIAARYVRDRDQFEGIVRRLADAGVTDIFVPGGDLEEPAGEFESAHDL
LVVLDDLDYEFEEVGITGYPEGHDFISDETLAESIAAKEPYATYIVTQLCYDSDAVVEWV
ETIRDRGVDLPVEVGIPGVMKYQRLLEISQKVGVGDSIHFLRKTTGIVEFVRQLVGSRGQ
YAPDDLIDGLARYAGDPEHRIRGVHVYTFNQTPDTESWRRGRLAE
>A0A853FX01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. R-74633|TrEMBL
MSNLDPLAAPLFADVAGDIDVSFEFFPPKTEKMEETLWDSIETLKPLDPRFVSVTYGAGG
TTRERTHNTVARIARETGIPAAAHLTCVEATKEEIDQVAEEYWAAGVRHIVALRGDPPRA
GEKYATHPGGYENAADLVAGLRKLHPFEISVAAYPECHPDSPSQMDDLDNLKRKIDAGAT
RAITQFFFEADTFLRFRDDAAKAGITAEIVPGIMPVMSFASVVRMSAMCGTQVPGWMERL
FEGLDDRPAARQLVAATLAAELSRKLYAGGVRQFHFYTLNRAELSYAICHLLGVRPKMPA
LVGA
>A0A1U7Q0S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epilithonimonas bovis DSM 19482|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYQNIDPLMEFKPPFIDVTTSREEYIFIE
RGNGLMERKITRMRPGTLGICSAIQHKYNVDTVPHVLCGGFTREETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEPTKGGNRYASDLVKQIHDLGMGEYLHGKIECKDESSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKYFDFVKQAREIGIDVPIIPGIK
PIATKTHLQLLPQVFKIDLPETLINAVLKCKTNTDVREVGVEWAIQQCKELLDFGVPVLH
FYSMGKSDNILKIGREVF
>A0A345V9I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. PM3|TrEMBL
MSPPSLIDTHPNLAGAAPVALSYELFPPRSAAAAESLWTTIGELEATDPDYVSVTYGASG
SNRGTAVELINRLVQETTLRPLAHLTCVGNSPQELAEIIGELLDVGVRGILALRGDQPKD
GATPPPGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPARHPESPSEAHDIEVLL
AKQRSGADFAITQVFFHAEQYADLLTRARRAGVTIPIIPGVMPLISLRRLARLGELTGVE
PAPELIDRLAAADTDAERTRIGVRATVDLANAALDAGAPGIHLYTFNEHAAALDVLDKLA
LPRPHRHGAQRRPAPSAATAGQLAS
>A0A329YRH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. AQ5-06|TrEMBL
MSPPSLIETHPNLSETAPVALSYELFPPRSPAAAESLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPEELAEIIGDLLDTGVRGILALRGDQPKD
GAPPAAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYANLVSRARRAGVTIPIIPGVMPLTSLRRVTRLGELTGVE
PAPELLARLAAADSDAERLRIGVRATVELANAALDAGAPGIHLYTFNEHQSALEVLDKLA
LPRQSRSVGRRSAILRRQLAS
>A0A0H5CVI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alloactinosynnema sp. L-07|TrEMBL
MVQRIHADKPVFSVEFMPPRDQADEKRLWNAIRELEGLDPAFVSVTYGAGGSSRDRTIRT
TGRVARETTLVSMAHLTAVDHSVAELRNVIGWYAALGIRNILALRGDPPGDPNGEWVKHP
DGLNYADELVALVRELGDFCVGVAAFPYGHPRSNDLDSDTENLIRKLRAGADFAIAQLFF
EPEDFLRLRDRVAARGYDTTLLPGIMPLTTPKILSKTVELAGAPVSARIAARLDPLVGDA
AAFRAEGIDIATEVSERLLAEGVPCLHFYTFNRAKATREVVGRLGLVPARA
>A0A6C6YXA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia mallei (strain NCTC 10247)|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A1F8QAR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_54_11|TrEMBL
MKAGEFVVTAEVAPPATVATNKLLKNIELVKPYVAAINFTDCPSASPRMSSWACSTFTVQ
SGAEPVMQIAARDRTRIGLQAEVLGSNALGVRNILCLSGDSMNMSAIPKGKMDILDMDSI
HMLWILRRMRDEAIYMDGRSIKFPPKYFLGAAGSPYASNPRIQAFREHKKVNAGAQFFQT
NLVYDADKLDDWLEALEQRGILDKVYILIGITPLKSLKVAKYMNEEVPGVTIPEKLVKRM
EAAGDKAEEEGVQIALELINAVKNKKGVNGIHLMAVGWEEIVPRIITEAGILPPDFVAPP
APAPKS
>A0A7K3UQD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MALKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSQLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFEGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRSAAKSAGAAA
LSLRV
>A0A009GWD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 1295259|TrEMBL
MTLADRVHSDHDIVPLEASKSYPDSIEKVLHFSGKARDIQEFERFLQQAQVANIQNLLLL
TGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLH
KKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGI
VITPHMLKVLAEEKQAGHTDRVYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIE
QYRHLELKALEELWNSLWHVTSGNEFTPEIARFSCQPTSKQLIKYRQLHVMHEAMFGSKI
AKGVGRFIFKASFWENALVAKVLIKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGL
ANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQTEILKEKLIPTVPLETRGTSSWKNWY
LATEA
>A0A7J2SQN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon|TrEMBL
MKISDVLSETEETRFSLEVFPPKTGVSEKIPIQRHLSNIFDTVEHLLRYNPVFVSVTYNP
EGKTKTTSIPLAAIIKQKYKVEAVAHLTCISTPREEVSKTLDVIDYFDIENILALRGDLP
SDSKEVKGLKHASDLVKEIKKHKKGFCIGVACYPEGHPECVTEEGEKDLEKDLLHFKAKV
DEGADFAITQLFFDNNVFFKFVEKARKKGVKIPIIPGIMPIRSYNTLNIVKRLGNITMPS
SLVKKLENNREDKNEIIEIGVEYAVEQCRWLMDKVPCIHFYTMDRWVSVDRILKELS
>A0A8J8TQ40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronococcus pandeyae|TrEMBL
MSSEIHSSATADGVIELLEEPRYELMPFDSMDEQLEHLPDGAEVAITTSPTLGIEATVDW
SERAADRGYEIVPHIAARYVRGEDHLEEIAGRLVDAGVTDIFVPGGDRDEPAGEYASAYE
LLAALEELEYAFADVGITGYPEGHAFLDEQTLSDSMARKEPFATYVVTQLCYDPDAIVEW
IGTIRNRGVELPVEVGIPGVMNYQRLLGISKKVGVGDSVRFLQKTSGILGFVRQLVGSRG
KYAPDELVEGLAPYATDPHYDVRGVHIYAFNQVPDLESWRAETLAQYR
>A0A7Z2NXK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas changnyeongensis|TrEMBL
MTPSLAQLEEARRALDAPLFADLSGDIGVSFEFFPPKTEKMDTQLWDAVQTLAPLGPRFV
SVTYGAGGSTRERTHATVARIVRETSLAAAAHLTCVEATREEIDAIADEYWAAGVRHIVA
LRGDPPVAGQGFAPHPGGYASAADLVAGLKRLHPFEISVAAYPEAHPEARSLDDDIDNLK
RKIDAGGTRAISQFFFSPDCFFRFRDKAAARGVTAEIVPGILPVSNVAQTRRFAAQCGAT
IPGWMDRLFEGLDDLPAARQLVAATIAAELCRRLYAGGVRDFHFYTLNRAELAYAICHML
GVRGNAQVTEKAA
>A0A350UWS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospina sp|TrEMBL
MKIQEILQEVRPAFSFEFFPPKDDDGFDQLFQTIDRLKSWNPAFVSVTYGAGGSTRSKTI
DLVGRIKNEIGLESMAHLTCVGHSSDEICSVLKSLQEQGIDNVLALRGDPPQGETNFVKP
ENGFGFASELVGFTRDKFPFCIGVAGYPEGHPECPDHRQGLEHVKNKIIAGGSFIVTQLF
FDNKVYFDFVKNLKDIEVDVPVIPGIMPILNLKQIKRFTKMCGATVPADLLARLESVQDD
PEAVREIGIDHATAQCENLLSQGAPGIHFYTLNRSRATLSVLERLKSISIGS
>A0A073IUA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistes jonesii|TrEMBL
MKNFFKLDKPTLSFEIFPPKGKGDLSKIFDTVDALASLDPDLISVTYGAGGTSRENTAEI
ASRIQNDYAIPALAHLTCIGSTREEMRATLGRLRDMGIKNILAMRGDIDGEGTKDFAHAS
DLIRFINENYKFNIFAACYPEKHIEAYSMEEDLAHLSDKCRFGVDVLISQLFFDNAYFYK
FRDSVRKLGISAPIEAGIMPVTSPSQISRMVTMCGASMPPAVQKIVRAYGHNSMAMREAG
IAYATNQIIDLLAEGVDGIHLYTMNLPEIAKRICENIRGVLYSLRVKRG
>J7GT49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Carsonella ruddii CS isolate Thao2000|TrEMBL
MKQISFELFPTFYCINNLIEKINMVKPNFISITCGKIDNYLFIKKNINFFKIKIVPHLIC
NELNKIIIKIILFIKLNIYNFLIITGDNYKLNSFYFVKNIRNLFGHTIKIFSSIYSENHK
LSINLNKEILFIYKKNKIGINCYFSQFFFNYNIINYFLKIINKTGIKKTIIIGIFPKKKI
NEVLIFSNYCKVEISNWITKNYYFFNLKNYYLKNIKNKNFHFYTFNNIKNLNYYFK
>K9AYJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei S18|TrEMBL
MSASALGSLLTSARYEILPTSGIIDRITDHVAPGRTITVTASAGLGLDATLSTAEQLQAL
GYDAVPHIAARMVQGRTELTEIIDRIGHAGIDTIFVPAGDATPPAGGYASALDLLVDLTS
MAPPISRIGVSAYPESHPLIPDDVTVQAMWDKRDYATHIVSNLCFDPGVVSTWLARVRAR
GIELPLILGIPGKVELAKLAKVAAKIGVGESTRFLRKNTGTFTRMARPGGYNPRKFLDRL
SPVLADPYMDVSGLHIYTFNQVKDTEAWRRKQLELLGDPDSSSIVS
>Q89UJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)|TrEMBL
MSGAMTDLTKPATADGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYGA
GGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPP
GGIGTPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVD
AGATRAITQVFFDNDLYFRYLDRVRARGINIPVVPGIMPMHNFKQARAFVTRAGTSVPDW
LAEKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRA
KSAQKAA
>A0A090RH98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. C7|TrEMBL
MGYTHASHIDALNQNIAELSEDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVT
YGANSGERDRTHSIIKEIKSETGIIAAPHLTCIDASCEELIQIADDYWHNGIESIVALRG
DIPPGGGKPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANR
AITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQF
EGLEDDATTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQP
>A0A239NF20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura meyerae|TrEMBL
MTDPVEAARELIRGAAIEVIPIKGAERAVAAIPPATKVTITCSPKFGLDRTLEHVAKAAR
AGHRVVPHLAARQVTGRRGLGEIAERLADLGVTDLFVVGGDAKVPEGPFESATQLLSALA
GLDHPFTSIGVTCYPEGHRQIPDEALMESLLAKQELADYMVSQLCFDPGALVGWLRSVRA
AGVALPLNLGLAAPLNSRKLLELSLRIGVGSSVRFLGKQHGLVNSLVLGRDYEPEKLVAE
IARQESFEDLGIAGLHLFSFNQVERTLQWQRGQTSALPA
>A0A1B1CQ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MMIAPQSESREKSPLADLLSHYSIEVTSRDLQSLESMTATLPQGCEVFIAHLPKEDIGLL
VRASAGLRDAGFVPIPHIVARNIRNRLELDTMLARLSEEAGVRHALVLGGDRDDAAGAFG
SSLDLIETGLFQAYGIDRIAIACYPEGHPRIPGAILDAALTAKIDAAARAGLDVLLVSQF
LFDPKPLLNFARRLRERGVTAPLSVGIAGPASRTKLLKYALRCGVGASLRALRERSEIAR
NVLSGETPEELLMEIAAAQATEPDLGISGVHFFTFGDPAQSIRWAEQQVDR
>A0A4Q1TXT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MALKNDARGRNIGVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTRAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIDDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRRQTKSAGAAA
>A0A085ZRA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium reichenbachii|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSINELYDNIDPLMEFKPPFIDVTTSREEYIYIE
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKVGGNHFAIDLVRQINNLNCGKYLHEVMDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFNFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>C0W5C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces urogenitalis DSM 15434|TrEMBL
MENTMSPSLAQPYTRHVAPKPSPASPEPSPAALAPSLTPAEPARPSLSLELFPPRPGRYA
SQTWGALDRLLAARPDFVSVTYRPRFITTAGGPTAAAGSPTRLHVVREHNPSEDVVAHVI
ATSRVPLMAHLTCLGYRKANVVEIVRLFLDMGVRRFLALRGDPPRGVAAEDVVGELRHAD
QLVRVIREVEAEYFDDGARHVQVAVAAYPAAVDYAREIGVLAAKQAAGADLAITQVFYES
EDYLALARAASYCGVTMPILPGIIPLTDLRRLTRLEDLTGVSVPTRLSQTLTSRQGASVM
TAGIDATLQLAGDLIEGGAPGLHLYTFNRTRPALDVISQFRLGGVLDGARPDRVTQREIA
RAYINAVPGSGARLTGRMPVAARP
>A0A0Q6X0R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobacter sp. Root1221|TrEMBL
MTSNFPVSLEFFPAKTPDGVAKYAAVRRELYALKPAFCSVTAGAGGSTHKGTLSMVQDIF
SEGVEGAPHFTCVGASTDSIRDALAQFRDAGIRRIVALRGDLPSGYGSFGEFRYASDLVA
FIRAETGDHFHIEVAAYPEMHPQAKSPQADLQAYAAKVHAGANSAITQLFFNADAYFRFL
DEARKLGADVPVVPGVMPITNASGLIRFADNTGAEIPRWIRLRLQSYGDDVESIKAFGLD
VVTDLCERLRAGGAPGVHLYTMNQSGASLALFKRLGW
>J2WCC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. AP49|TrEMBL
MTQTDRAQNNPGGPLYANLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFVSVTY
GAGGSTRERTHNTVARIAKETPLAAAAHLTCVAASKGEIDEVADAYWEAGVRHIVALRGD
PPEAGTAFQPHPDGYKGAAELVEGLLKRHPFEISVAAYPETHPEALSAQSDLDNLKRKID
AGATRAITQFFFEADTFFRFRDRVAAAGIDAEIIPGIMPVSNFAAVQRMSAMCNTDVPAW
MGRLFDGLDQHPAARQLVSATLAAELCRNLYMGGVRDFHFYTLNRAELSYAICHLLGLRP
QVAAELEKTA
>K6XDP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineosphaera limosa NBRC 100340|TrEMBL
MCGLAYADRMLHRPSIPDLLRSDRPAFSFEFFPPKDDAAEATLWEAIRRIEQVDPAFVSV
TYGAGGSTQDRTVRITEQIAQVTTLEPMAHLTCVGASVAQLREVIGAYAAAGIHNVLALR
GDPPGDARATWAPHPQGLSHADDLVRLISSLGSFTVGVAAFPDVHPESPDLGHDVEVLVR
KADAGAQFAVTQMVFDADTYLRLRDEVAARRELPIVPGLMPVTNFAQIARMSQLMGTPLP
AAVIARLQPLADDRAALRAEGVAIATELGERMLAEGAPGLHFITMNRSTATLEVLGRLGG
IPTDCQRRIRAGARASRPVAAAASPVGAA
>A0A8I6YWJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hordeum vulgare subsp. vulgare|TrEMBL
MKVIEKIQEAAANGRTVFSFEYFPPKTEEGVENLFERMDRMVAHGPNFCDITWGAGGSTA
DVTLDIANRMQNMVCVETMMHLTCTNMPVEKIDNALDTIKNNGIQNVLALRGDPPHGQDK
FVQVAGGFSCALDLVQHIRAKYGDYFGITVAGYPEAHPEVILGEDGATEEAYSKDLAYLK
RKVDAGADVIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNL
GLIEESKLSRTLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPQGRWGDSRNP
SYGALNDHQFTRPRGRGKKLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPE
TTIIDDQLVKMNSKGFLTINSQPAVNAEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLD
QLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWSRGWACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISGDLFAAFKEI
>A0A6P6AAF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Durio zibethinus|TrEMBL
MKVIEKIQSLLEDQGKVVFSFEFFPPKTEDGVDNLFDRMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDAIGSEGVATPEAYQNDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPDEITAALEPIKDNEEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRFLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSRN
PSYGALSDYQFMRPRARDKKLHQEWATPLKCIDDIQEKFKNYCLGKLRSSPWSELDGLQP
ETKVIHEQLGRINLKGFLTINSQPAVNGECSDSPSVGWGGPGGYVYQKAYLEFFCSMEKL
DALVNKCKAFSSVTYFAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFMVW
KDEAFEIWSRSWAALYPDGDPSKKFLEEIQSSYYLVSLVDNDYMSGDIFAVFEDL
>A0A8B6S6P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium meliloti|TrEMBL
MNGRTPYPVDWDGLRFSFEYFPPKNDEMETQLFQTVTALSVFAPAFVTVTYGAGGSTKAR
SLTTVKRMIGEMEIANTAAHLTCVGAPKAEVDAVIDEFLACGVRHFVALRGDPQGGIGSV
YEPFPGGYENAAALVKALRARGDFEISVSAYPEKHPESPDVAADIDMLKRKVDNGATRAL
TQFFFDNDDFERYLERVRRAGIAIPIVPGILPINNLTQVQKFAGLCGARVPESIVSRLGP
IDDQPEERFREAAHIAAEQVADLVRRGVSDFHLYTMNRPQLITAVRELMGYDPEIAPAQP
ADTERSVRAVARA
>A0A7Y4FGA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 99-8-1|TrEMBL
MSYTHASHLDALNQNIAELGDINVSFEFFPPSSEKMEETLWNSVHRLKKLQPKFVSVTYG
ANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASRDELITIANDYWQNGIKNIVALRGDI
PAGGGVPEMYASNLVELLKEQHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVSAGIDVEIVPGILPVSNFQQASRFAKMNNVKIPGWMAQQFEG
LDEDPTTRQLLGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPTV
>A0A1V0PHC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSDNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYLDKTQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>A0A8H5T8A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella circinata|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLASDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>I9P9P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 412 str. F0487|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVESCKNNNEVKQVGIEWAIQQSKELKATGVPVLHY
YSMGKSDNIVKVISEVF
>A0A641AQJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium fastidiosum|TrEMBL
MAFDDHSLVAALRAPAPSYSFEFFPPKDDDGEDLLWQTIADLEPLDPTFVSVTYGAGGTS
QERTVRITARIAEQTAMRPVGHLTLVAQTRGEIESVLKQYAAAGVDNVLALRGDPKGGPR
APWEPHPDGMTYAVDLVELARQLGGFEIGVAAFPEGHPDAASLDHDAEVLVAKARAGADY
AITQLFFRASDYFGLVERVRALGSDIPIVPGIMPILNFAQVARMAELSGAEMPAEVLAQI
EPIADDKAAVRVKGIELATQLCRDLLAGGAPGLHFITLNRSKATREIFEQLRADGLV
>A0A2Z5Z6T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYLDKTQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPYVHPESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>A0A0Q8ZMM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Root9|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMTTAKQLASFSPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>E4LD31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. oral taxon 158 str. F0412|TrEMBL
MTLREKHQQGKFTITVELDPPKSSSAEKVFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDAPTSFYIGATGNPGAPDLEIERQKLAAKIQNGA
HFVQTQPIYDLEQAKRYIDTMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A653A3X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfatiglans sp|TrEMBL
MKLKEALQKKRFVVTTEIQTPLDQESGGLIIQNLERIRGRVDGVTLSETELEGVVGDTIK
TCELLKQNRFESIYQTTTREKNRIQLQKDLIAAHQAGVENLLVFTEDYRITGDSLQEMMF
FHVDAGKLKSVLDHIREGHTVDGREIPEKANFLLGSGVESVWGRNVPDLELREMEEMVRV
GTGYFLTTPVFDLDRFQKFLSRTNTFGVPVIAEVLILRTAGVARFLNRHLRSGLVPDWVI
RKLAQAADIEKASLELFADTIKGLREICDGVHIITIGGESKLRQYLDAAKLR
>A0A3E0LED9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis wesenbergii TW10|TrEMBL
MTTRLQRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPVHN
>A0A355Q8J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIIEMYHNRPFVFSIEVFPPKTEEGMVNLQEKLRTFSLFKPDYISVTYGAGGGTRQNTQ
QLAGFIGNELGIEVLAHLTCVSHTRKDVSLLKEQFLSEGVENIMALRGDPPTTEKTFEPM
PEGYRYASELIEDLSRDRRFGIGAAGYPETHIDAISSKMDRYFLKQKIERGAEFVISQFF
LENQKFLNWRDQLYREGVRIPIIPGLICAQSSSQIQRFAKMCGCMVPSDLIKNLERFEGN
AADSLRVGLDHAEKQLNGLIREGITGVHLYALNRSEVVNALGPTMVGLMSRTDLRSSLEN
DGRLGF
>A0A7V0JSK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTKTPSKLEKILSQGHLAVTSECGPPRGSDPAVIVKKANLIKDHVDAINVTDNQTAMTR
LCSLASVIHLKLMGLEPILQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQRFGDCP
EAQNVYDIDSMQLISMVRHMRDKGKFVGGDEIDRPPQMFVGAAANPFADPFEIRVPRLAK
KIEAGAEFIQTQCIYNVDKFEEWMRLVRDRGLHEKVYILAGVTPMKSVGMAKYMKNRVPG
MDVPDEIIKRMGNVSKKNQPEEGIKICVETIQRLKEVKGVRGFHIMAIEWEERVPELVER
SGLFPRPNIS
>A0A7C3JKI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLADLYARAGLTLSVEFFPPKTDKGEENLFSEIEVIKRFHPGFCSVTYGAGGSTREKTI
DTVDAIHQRCGLEVMCHLTVIGQSKDEARAILQRLKTKGIENLLALGGDPPQGTTDWRPH
PDGFRHAIELVREAVHLGGFSIAVAGFPEVHPRAMSRQSDLRYLKEKVDAGAAAIITQLF
FDNEDFFRFSDDLIKLGVDVPVVPGILPILSASQVRRFTALCGARIPAALEQQLSKVEND
DNAAVELGIEYASRQCEGLIRYGVRGLHFYSLNKAYSFQAICNNLALSRQTAGS
>A0A7C5WTI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MFDTFCSTLCGPNQFITVEITPPHGGSMSKIISEITSLGLDKKVIGFTTTDNPLAKLKMD
SVLAAIKIQQAFNKPVIATMSMRDKNKLSLQSTLLGANNFDIRCILALTGDPAKLSDQPE
VKGVLERDSTLLLSIIYHLNSGSDYSKKELQTPLKPIYPFAVSNAYAKDMKALQKRMIKK
LNYGARAIITQPIYDTQSAKLLLEIFQEAKEISIRETAKDAVLILGLFPIVATKTVNFIN
GHVPGIRVPKMIIDEMNLASMDGKEKEQEVGFGISKMVFDQTMALHPKVHLMTHNRFDLC
KQLIG
>A0A7X8CG86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSVQSNLERVLNEGTFAVTGELGPKRGVDTVHLREMAQLIKPYCDAFNITDNQTAVVRMS
SIATGIMLKQMEMDPVIQIVTRDRNRLAIQADVLGAAAFGVMNVLALSGDHQTMGNHPGA
KNVYDLDSMQLIQCLVGLREGRFMNGEELETDPPHLFVGAAINPFGHPMEFRVTRLAKKI
KAGAQFVQSQPVYAMDIFKKYMEDVRNRGLHEKCHIMAGIIPIKSIGMAKYMRDKVAGVI
VPNEKVERLQKAADTVSDKKERIIKVREEAVNMAVEEIHQCMEIPGVHGVHIMAVAWEEI
IPEVLKKAGLDKERPKYKS
>A0A223N099|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio qinghaiensis|TrEMBL
MGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSAQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASRDELIQIADDYWHNGIQNIVALRGD
IPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLVNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFN
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A2E9R825|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTHEWDTFKLMKIIDKINRCKQTGEHCFSFEYFPPRTQAGVENLYARIDRMGRLHPQFID
VTWGAGGSTAERTMEIVTHTQNLSGLETMMHLTCTNMSRKDIAAALCTARENGIQNILAL
RGDPPIGEENWEQHGDGFSHAIDLVRFIREEHGDYFGICVAGYPGGHIENPSYERDMHFL
REKVDAGADFIITQLFYDVDLFIQFMKDCKKMGIDCPILPGIMPIHSFNSFNKLTQFCRD
IPEEIVANIQAIRSDDEAVKDYGFTLVKGMCERLLEAGVDGLHFYTMNLESIVTHLVDEL
NLIPEQVQRTLPWRRSANEKRLQEEDVRPIFWANRPKSYIQRTMEWDEFPNGRWGDSRSP
AFGELVPHPWGHVQVHPKRRKKMWGEAPETFEDVKSVFLKFCEGDIDAIPWFDSPLELES
GRILEQLLKLNEAGLLTINSQPSVNGVPSDDSSVGWGSPGGYVYQKSYVEFFIDGRHIET
LIKVLKRHPSISFQAINKEGTVYSNCDTVNAVTWGVFPGKEITQPTIVDPDSFVVWKDEA
FDLWLYVWGALYPAESPSRELFQQIYKEFYLVNVVDNDFVKGDIWSVLDEVVKAISS
>A0A523CDW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSRLERILTSGEFAVTGELGPPKNGNAEHVREKARLLKGSVDAVNITDCQTAIVRMS
SISAGLLTLAEGVEPVIQMTCRDRNRIGMQSDILGAAALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMVKTMRDEKKFQCGEVIKSHEPKLFLGAAANPFAGPSEQFRAARLAK
KVANGADFVQTQIIYNVERFARFMQAVRDLGLHKKVHILAGVTPPKSVGMARYMKSSVPG
MDVTDEVIKRMQGAKDKEDEGINICVDIIRQVREIEGVAGVHIMAIEWESAVPEIVSRAG
LATRPVFVDEPVALAAPVSAIEVRTTVAGGEEGDAVLAAAKVEAEKIIAAAKAEAAQYRA
SATAGTSGAGTVDQARIEIEEAGEDAMNEKERQMALDSVRLGLDALKKAYGLSDDQFDAL
VKFAGAEAILKREPLLAVPASPAPAPVAQAAPAAPAPVPDESAAKKAAEAAAADEAKKAE
AAKKAAADKAAAEAKTAEAAKKAAEAAAADEAKKAEAAKKAAADKAAEAAKKPAADKAAE
AAKKPAAPEAKKAAPAASAAAVGAAELACEKTPLSERAAKVPEASYKQAYTGAIRETALG
EGPSGIKVGGSNTLSFHLFEGTMGNSPKIAFDVLDVKPDEWPDSLARHYQDVLDNPVAWA
QKCVKEYGADAICISMVSTDPNGLNRPAGEAAKAAAEVVKSIEVPVIVWGCGNGEKDTET
LREITSLIGDKKVCLAPLSDSNYRAIGATAMAFQYPMVAASPIDVNLAKQLNILLENLGV
SLDSVLIDPSIGALGYGIEYTYSVMERIRLAALTQKDEKLQVPFICNLGREVWKAKECRL
PSDEMIGDQETRGILMEAITASCMLMAGGELMIMRHPRAVALTKSLINGLMG
>A0A7W0QJ94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MARIGDLLRTGRTVSFEFSPPRDDSAQLSLGRTIAELEPLDPSFVSVTYGAGGSTRERTR
DVVTWVRRETGITPMAHLTCQGHTRAEVAQLLDEYQEAGIENILALGGDPPKDPADQRPS
EYTYATDLIDDLDTRNHFSIGVAAHPEVHPRSPDRATDRLRLAAKLRRADFAITQFFFEA
HHYIEMVDELADLGVDKPVLPGIMPVTNGRQVTRMAELSGADVPSFVTDRIAGLDNPADV
RSAGVEMASELCAALLAAGAPGLHFYTLNRSTATREIYANLGLTTS
>A0A7V9B6D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MKDLLARGRTISFEFGPPRDSDAEQRLQKALVDLEPLEPSFVSVTYGAGGSTRDTTRRIV
EQIASSTSMTVMPHLTCVAHSREQITEIVGGYRDTGIENLLALGGDAPADGSEYPTDFRY
AAELIEAAREIGDFSIGVAAFPEVHPRSPDNHTDRRFLAEKLRVADFGITQFFFDTDPYF
RMVEELAALGVDTPVLPGIMSFVNVDGLRRMAGMNASTIPDELHRKLDLAAGTPSAVREL
AVEVGTELGQKLLDGGAPGLHLYTMNFSRGTTEILANLGLR
>A0A842LGU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccales archaeon|TrEMBL
MKAGSNLEKVLEAGHFAVTVEIGPPKSANPESVRHHARMLKGYADAFNLTDNQTAIVRLS
SLASAVICLQEGVEPVMQMTCRDRNRIALQSDLLGASALGIKNVLCLTGDHQTFGNEKGA
KNVYDIDSIQELLIFKKMRDEKKICGGEELEEAPKVFLGAAENPFADPFEFRVTRLAKKV
NAGADFIQTQAIYDMERFEKWMEGVRERGLDKKVHILAGVIPLKSVGAARYMKNKVSGMI
VPDSIIDRMRKAKDPKAEGVKICIEQIEYLKTVKGVHGVHIMAIAWEEIVPEIVKQAGLY
PRPSV
>A0A318D5W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKNNFVEYLNEKVMLGDGAFGTYLFEKGVDLTKNTDLLNISDPDLVYSVHEEYIRAGSEL
IETNTFGANSFKMLRVGHEHKVREINLKGAELACRAAGNEIFVAGSIGPTGVNFSLENDE
VESGTVQEAFVEQMTALLEGGVDLFILETFTYLDELLLSIGTAKRIAPDIPIVAQMVYPF
HGRTAIGLDALDCGRATAAAGATVVGTNCGRGVKAMLSAVERLSPLKDAVFLSAFPNAGL
PEIVEHRMVYSTPPAYMADKVAEMVKFGVRLIGGCCGTTPAHIHEFRKHLHIKRHKTTRV
VTSVEKFSGLTEERKNSIGRGGMIESLRSDRIPVLVEVDPPRHLDIEGILTGARALADAG
ADAITLAEHPLAVLRADNLSLAHRIREETGIQTVLHLTCRDRNILGLQAQIMGAHVLGLE
AILAVTGDPATSTDQPCVSGVFDVRSFGLVQMIDQFNRGLNMAGASMKKRTDFSIGVAFS
YRSANPDLQISRLERKADLGANFVMTQPIFDRDAVEAMMERTQHLDLLIFTGIFPLISAR
NADFLHNEIPGISIPREIRERLWKYEKVEDQRKAALDLTRKLIADITPFAGGLYLISPLN
KWEIPLTLVQELRASGH
>A0A800IDE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MVQRIPDVLAKRRTLSFEYFPPPPGPAREAALRSAARLAHRRPDFVSVTYGAGGSDRART
RQMVADVAASHVSARHRCPVMPHLTGIGHTKAEVRALLADHQAVGVANVLALAGDPRPEE
TVAGGFRYATDLVTFIQEETDVAVGVAAFPEVHPRSPDRATDRRHLAHKLSLADFAITQF
FFDEKVYAQLIDELAALGCTTPVIPGVIPVTNPSSVKRFAEMNNSAIPVDLWNRLEAAEP
KERLRIAVDEAAAMVANLVDLGAPGVHLYSLNSAEAVEGVLDLHGDDLSSSE
>A0A7C3LNW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
QKRIIKKLNYGARAIITQPVYDLENAKELLELFEEAKTISIRETAKEAQLILGQFPIVRA
KTANFIDDKVPGISVPKTIIDEMNLAQMDGEEKEQEVGFALSKRIFDELMGVHGKVHLMT
HNRFDLCSELIG
>A0A124HFC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces yokosukanensis|TrEMBL
MNPALTATPAVGAALLDDFSLEMTGKDVPRLEEARGSIPRGTRINITFLAGEDLGMRLAA
ARAVKRLGFVPVPHISARRLPSRAALEEFLSGLAADGTAENVFVVGGDPARPEGPYEDSL
ALLRTGLLQDHGVRHIGISGYPEGHPVIADPALWSALTDKAAAIGAHRFGGDVITQFGFD
ADPVLTWLEAARERGVHLPVRIGVPGPAGVRRLLGYATRFGVATSASVARKYGFSLTNLM
GTTGPDRFLHTFAHRYDPERHGVVKVHFYTFGGLRDTAEWIAGFRRSLHGSA
>A0A661RCJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
IGAAANPFADPFELRVPRLAKKVKAGADFIQTQCVYNVEKFEKWMEGVRERGLHEKISIL
AGVTPMKSVGMARYMKNKVPGMDVPDELVIRISGVPKDKQAEEGIKICVETIEHLREVDG
VRGFHIMAIEWEQKVPEIVERAGLYPRPKI
>A0A509L1P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSTKTPSKLEKILSAGHLAVTSECGPPRGSDMDSITKKGELIKDYVDGVNITDNQTSVTR
MCSLAACIKLKLMGIESTLQMVTRDRNRIALQSDILGAAAFDIYNILCLSGDHQSFGDCP
TGQNVHDLDSMQLIQTARHMRDEGKFLGGDDIKKPPQMFVGAAANPFADPFEIRVPRLAK
KIAAGAEFIQTQCIYNLDKFEEWMRRVCDRGLHEKVYILAGVTPFKSAGMAKFMKNRVPG
MDVPDDVVKRLSDTPKEKQADEGIKICIETIQRLKEVEGVRGFHIMAIEWEEKVPGIVKE
TGLYPRPEV
>A0A661K0G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSSSRLERVLTAGHFAVTSECGPPRGADPEAIRRKGELLRGVVDAVNVTDCQTAVVRMS
SLSSCLLLKEMGFEPILQMVTRDRNRIAIQSDILGAAALGINNILCLTGDHQRAGDHPQA
KNVFDLDSVQLIAAVKAMRDEGRFLNGEELTVPPKLFIGAAANPFADPFEIRVLRLAKKV
AAGADFIQTQCIYNLERFREWMKQVVDMGLHEKVFILAGVTPLKSVGMARYMKNMVPGMD
VPDELIARLKGVPKEKQPEEGVKIAIETVQQLKEIEGVSGVHIMAIEWEEKVREIAEGAG
LLSRPEV
>A0A533RBT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSQLSQNLAAGEFVVTAEVAPPKGIDLAPVLATAEKLQGVTAVNVTDNQGANMRLCALVL
AGELRRRGIEPVLQLTCRDRNRVALQSDLLGAAALGIENVLLLSGDHSKFGDHPDARPVF
DLDAVQLLDVVAGLNRGVDMAGKPLAGTPRFFPGAAVNPAAEPFELVLQKVRKKVDGGAR
FFQTQAVFTRVELERLAAAVAPLNVPVLAGVLLVRSAKMARFLNSSIPGMCVPDEVVARL
EQAADPLLEGVAIARETVGWARTFCQGVHLMTLGHDETIPEILR
>A0A1F0BHI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC078H03|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFKYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSGLLTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHEATHSLFKHHSQVSAL
>A0A2S5J000|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter pityocampae|TrEMBL
MRGSRTDRTGGGGTSVKDSEPSPTYPALSYELYPPRNAAAEDSLWTTIRRLEDTRPDFVS
VTYGAAGSNRDAAFTLLRRLLTETTLKPLAHLTSVGTSREDLTEIVDRMIGGGVRGILAL
RGDMPEDAHPVPDEVEHADGLVRLIRDVEAGRTAQLAAGRISVGVAAYATRHPESPSLEH
DVEVLLAKEAAGADFAITQVFFTPSDYSGLVTRARSAGVTIPIIPGVMPLTSTRRLEKLS
SLAGIDVDDALWSRLDGADSDAERRRVGVDATVELARSALEEGAPGIHLYTFNEHEAALD
VLDALDLERPPLAGLPASL
>A0A496XXM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MYENFINKLQNESFTTLETTPQHEPTFDDIITNIKSKNIINKIDGFTVTDNPLSRLKYSS
LLGSIKLKQNFDKPVIATMTMRDRNKLALQSDLLGANDFDICSFLCLTGDPAKISDQPQT
KGVLEGNSNLLLKMIYSYNNGMDYSGKMFKKTIKPIYPFTVINSYAKNFKTLEKKMLIKI
KYGSVGIITQPVFDITNAKKLLDSFQTVTKLFDDNRANCQLVFGIFAITRLRTAIFLSSH
VPGINVPQTWIDKLSRASKISEKEEYKVGMKLSLNLYKDIKKLHNKTHIMTADNFDIAKV
LLDV
>A0A661JZ78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLDKDFIITAELQPPKGPDTSRFIEKARVLKHKVHALNVTDNQRATLRLSSLAGCTILAR
EGITPVFQVTCRDRNRLAIQSDLLGAHALGIRHVLAITGDDISAGDHKEAKQVFDLDSIQ
LISIIDNMNKGFSDSGFALQGSTDFTIGAVVNPFSIPEELNLLRFDKKISAGARFFQTQA
VYDIDGFKKFMDKVAGRGVKILAGILLLKSLRMAHFINQNVPGVMVPDNLMEELETSSVP
LMKGMEIAARIIRELKGVSDGVHIMAMGMEERVPEILEMV
>A0A661LBF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
GDHQKFGNHPQAKNVYDIDSMQLIHAVKTMRDEGKFLNGEPIDEPPKLFIGAACNPFADP
FEFRVYRLAKKIEAGADFIQTQCIYNMDKFRQFMKRVVDMGLHEKCYILAGVTPMKSVGM
ARYMAKQVPGMDVPDSLIKRLQGAGKGKVAEEGIKFAVEQIEEFKEMEGVAGVHLMAIEW
EHRVPEIAERAGMLPRPKV
>A0A2D5V9H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MIAEALSIPGPFLREARAPCTNWSLEIVPKHAESVRDLPQDIREIYITMVPGTPWVDVIA
AARTVHRLGRSPIPNITARSIPDTASLEQLLLQLKEFRVEQALLIGGGIPEPAGEFTSVL
ELLQTGLFEKHGLLDLDLAGHPEGNPEDPHAEQSLLDKLTWGREHGFSFRIVTQWCFDAD
TVNDWIFRLRELGVTEPLHIGVPGPATMKTLMRFASLCGVKASATVLRKQGLHLTPGCCS
>A0A661MQB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSKLKEKLESGEFVVTVGLYPPRGADTGEFLAILSKLAGKVDAINLPDSRGASIRLSALS
ASILAKEKGLEPVMTVSCRDRNRIAISADLLGAHALGIDTVLCVSGDYVSLGDVPQAKPV
YDLDSVQLINMIRQMEAGQDIGGNELKGSPKFFVGCVANPIADPIEPHLLKLQKKLTAGV
DFIQTLDLYSVEGTAEFLNFLEDKGVKALAGLRLVTMADIEQNEKGRVVGNEIPSEVISE
IKSASTDVEALARAQEFLVAMIKDIRAENRWSGIHLTMNGHEELIPQILEQAGLGK
>A0A661KL31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGWRERLEGGGFLKVVEVLPPKGIDEKGFGERLIPLRGRVDAIYIPSLQGGVMRMSSWAA
CKYLQEKGYDTIFEVSCAHQNRVALQAELLGAYLLGLENVMAVPGDDPKLGDHPEAKGVF
DIDLIELLEGIRRLQKGYDMSGGDLEGSPRFCVGAKLDASARGHVLDLEMKEMEKKIRLG
VEFFITTSVYDLGQFETFMQKAQTFGVPVIAGLMVLKSAGMARYINKHVEGVFIPDEIIM
RLMKAPDKIAASIEIAAEMIRGIKDLCQGVNIISIGWEDKIPAILEEAEG
>A0A1Y4AEE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. An307|TrEMBL
MRIDNIFANARAGGRIPVSFEMFPPKGELTLERAREAAEKLCACAPDFISVTCSAGGTGD
SSATADIAAMIERDFGVSSVAHLTGIGRTRAELAERIAAYRKAGVENVLALRGDMPEGAD
AARGDFSFAYQIIPDLVEAGFCVGAAAYPEGHIACDDLAESVRHLRLKQDAGASFLVTQL
FFDNDLFYRFRELADAAGITVPITCGIMPFMSKQQVTRMVFMCGASLPSPVIKLLARYED
DQESLMHAGIDYACRQLEDLAAHGVDGLHVYTMNRPSVARAAIAALGR
>A0A3B8YYC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MERVGTIEAKRLRKGGGVLYGGGVRIDQILARPDPVFSFEFFPPKTDAGREALVGTIDEL
KPLDPAYVSVTYGAMGSNRGQVIEIVSEIKNRIGIEAMAHLTCVGHTREELSSVLDDLAS
VGIENVLALRGDPPPGTDFQATRGGFAHAADLVALIRKRGGFCIGGAAYPEVHPDAPDAE
TDLGHLRAKVGAGTDFLVSQLFFDNQDYFSFLTQVRQAGIEVPVLPGIMPVTNLGQVKRF
TDMCGAALPADLLRALEEAGDDEAAVLEIGVEHALQQCRDLLKGGAPGVHFYTLNKSAST
REILTRLRADD
>A0A509LF59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLTTLFDKNEFVITGEVGPIKGAISRDKSIEPICAIEALQLQQHVHAVNVTDNQSAVMR
LGSLAASVRLQTNGIEPVYQLTCRDRNRLALQSDLLTAYSLGIDNVLLLTGDHIQLGDHK
EAKPVFDLDSVQLCEMARGLNNGSDICGNSIENNMDMALGAVVNPNFEPLDLQLMKMKKK
IDAGAEFFQTQAVYDVKLFEKFIKKAEKFNCPIQVGIDVLKSPQMGKFMNKNVSGIQVPD
EWIDEIGSVAKEDHKKKAAEMAGRFIKEVKS
>A0A2S6SZ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha5_Bin6|TrEMBL
MATNYKELLIKELIKDFSIETTPNVYNKYGTFIEMLPKKNDVYVTYLPDENPDNVVNTCK
KLNLEGFDVIPHLPARTIKDIADLEKYIGSLSENAGCKKILIIGGGGNQKGEISSSIEVL
KTDLLSKFNFTQVGVAGHPEGSPDISNTELDKAIIEKNNFANNVDFKIYIATQFFFEASI
FEKWEYHLNSLNNKLEIHAGIPGPATLKTLISYATSCGIRNSIRFLSKQALNITKLASSK
TPDKLITDLALYKQENPASRLAKLHFYAFGGIKKTSEWLSLILDSSLEINSNNEFKPDKK
>A0A3D0I1L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIAEAFGRGRPVVSFEFFPPKTEAGFRSLYRTIGELKHLDPGFVSVTWGAGGSTRRATV
ELVARIQQEIGITAMAHLTCVGSTPQELGEILDRLEGAGIENLLALGGDPPRDQPGYRPT
PGGFTYACELVSFAHTRWNFCVGGACYPETHPRAPSAEADLAHLVRKVRAGVDFLITQLF
FDNADYFTFVARARAAGITVPIVPGIMPVVSRQNIVRITALSGARIPPELAARLELAEDD
PVRTLEVGVAWATAQCRELLDRDAPGLHFYTLNQSPATRRIHASLFGE
>A0A226IAI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium oncorhynchi|TrEMBL
MKVTEHIENAKGNTLFSFELIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNHFAIDLVKQINDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVYKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A661IYI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MVFRERLRDVDFVKVVEVLPPKGTNGVEFERRLIPLKGLVDAFYLPSLQGAVLRASSWGA
ALFLQERGFETIFEISCIHRNRLAIQADLLGVGLLGLQNVMLLEGDDPKWGDHPEAEAVR
DLGLMELIEAVRSLKEGKDLAGGDLDGAPDFCVGTKVNASLKDEGLEREWERMREMAERG
VEFFVTTSVYDLGQLERFMLGASQVGRPVIAGLMVLKSAGMARYINKHVPGVLIPEETID
KLLRAPDKAVTSVKIAAETLRGIREVCQGVNIIPIGWEDKVPQILEEAGI
>A0A2N2H0B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-21|TrEMBL
MASPFKKALQSGKFVVTSEVAPPKGANLDRMKHHVELLRDKVDAMNITDHQSSIMRYPSL
GGALLVKEMGGEPILQMTCRDRNRLALQADLLFASSRGINNVLCLTGDSVILGDHKEAKE
VFDLESCQLLSTIRLMERGKDLGGNALESPVSFCAGAIVTPEADPIEPQLIKFEKKVEAG
AEFIQTQAVYDLDNFKTFMEYAGKFPVKILAGIILLTSAPMARFMNKNVAGIHVPQELID
EMASAPKGRALQKGIEIAGRMIRRIREEKMCDGVHIMAIGKEEVVPEIMSAAGLL
>A0A645ESN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTKFSAHLEDARQLKDIADALNVTDNQCSIMHMSSL
AFSKLLLDDGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDYPTCGDHPGSKP
VYDLDSVQLIELVRKLDSGIDFAGNKLDGGTSFCAGAVSGIDPEKTMQLIKLEKKVKCGS
DFIQTQAVYDVGMFEEFMEAVNHLEVPVIAGLIPLKSLGMAKYMNENISGIHVPEEIMLR
MKDTDSPLEEGLSIASETIKELTKLSRGVHIMPIGSHKNTPRLLSMAGISQK
>A0A7V8FER6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTQLSFEFYPPKTDEQRGQLDRAAAQLKAFAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GLEAAPHLSCVGGTRREIRELLKLYRAIGCRRIVALRGDLPSGMGFPGDMRYAAELIAFI
REEHGDAFRIEVGAYPETHPQAPDTLTDLKHFKAKVDAGADAAITQYFFNADAYFHFVEQ
AQRLGVGIPIVPGIMPIANFSQLRRFSEQCGAEIPRWISRRMQAYGDDSASVRAFGAEVV
ARLCERLVDGGAPGLHFYTLNLARPTLAVLQQLRR
>A0A7D0GTJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAGTSSQAEAFINAFSLEVSAKAMPALRAEATRIPRGTIISIPWLASEDDDARLAAART
VRELGFEPMPHLSARRIGSHAALERFLERATGEAGVTRCLLIAGDLATPVGPFADSASII
ETGLLEHFGIKVVGIGGHPEGHPVMSADDRWQVLGRKCQGIEARGMAPLVVTQFAFDADT
VLAWLDALRARGITVPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVKGLTDAHGPVSPHFFPFGGITPSLEWIAQYRQRVCGSGR
>A0A1F4YAQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium RBG_16_53_22|TrEMBL
MAINFKAKLDGGIIICDGAMGTYLNQKGISYDRCLDELDMSMPKLVGEIHREYIHAGADM
IETNTFGANRFRLALHGLENNVRDINIAGAKIAREAREISGVDIIVAGSIGPIGKPLEPI
GKVKFNEARDAFAEQAGALLEGGVDLFLIETISSLDEMLAAVEGVRGISDLPLVAQMTFT
AEGTTYLGHTPADMVSRLMPLGINVIGANCSVGPQKMLEVVEQLSELGVEYISAQPNAGL
PRYLGGRFIYLSSPDYFADYAKSFVKAGARIVGGCCGTTPDHIAAVVRAIRGSDIRRGPS
VSRIEGRHEKKAQEPVGGALTRFYEKLKKDFVVSVEIDPPKGTNPAKLIEAAAKIKNAGA
DAVNVADSPMARVRMSCMALAYLINSAVDIDIVLHYTTRDRNLMGLQADLIGANAVGLRN
ILALTGDPPSIGDYPQATAVYDVDSVGLIQVISRLNSGTDLAGNSIGNPTAFSIGFGANP
TAPNLDFEVSRIKLKLEAGGQYMMTQPLYELEPLLRFLDIVKPDVPILLGILPLVSFKHA
QFLHNEVPGISVPESIRRAMEKAGDKSAKVGGELAAEFIEKARGFVTGIYLMPSFGRFET
CIELVEVLKRFKPIDASERGFHRKPG
>A0A1G8JE67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natribacillus halophilus|TrEMBL
MTFLERLQDEIMLGDGAIGTLLYARGISGSIEDANRHEKEMVISAHKEYIAAGAQVIQSN
TYAANALKLDNYGLAKQVTTINAEGVRLAKQAAIGEDVFVAGTIGGIRDGRASHFSNDEV
KTTTETQAEALLSEHPDAILLETYYDLHELVQALRIIKRLSPHIPVISNISLGDVGVLHG
GIPINDALLRLANEGADVVGINCRMGPAQTIASLEEVSLPEGVFLSAYPNASLPGIQDGR
LVYQSNPEYFKSQASAFREQGVHLLGGCCGTTPDHIRSFREKLQHLSPLRKPRAKVSAAW
QQQAADIGETIDLHKKESSMIVELDPPKSLTKMDKFLQGAEALHDAGADAVTLADNSLAT
SRIDNLAAATLMKQQTGAHPLLHIACRDRNLIGMQSHLLGLHALGIRDVLAITGDPTKVG
DFPGATSVYDFTSFDLIRLIKTMNEGFSHSGRPLGLETQFKVGAAFNPNVSSMDKAAKRL
EKKIVAGADFIMTQPIYDIETMERVKEATAHLDIPIYIGLMPLINGRNAEFLHNEVPGIH
LTDEVRQRMSACGKDVQKGEEEGMAIARDLQAAALDLFGRIYLITPFLRFHITAALTNEA
KAHSSQRSSV
>A0A8H4TCE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium gaditjirri|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELLE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNNWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A7T3DVL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIITALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETLADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFEIVGACYPEGHPDSPNQILDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A850S3X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariprofundus sp. KV|TrEMBL
MKLSEILGTATKPLFSCEFFPPKTDKGEENLWNCLRELQSINPAYASVTYGAGGTTQDRT
KGIVTRIKDETGLSPVAHLTCVGASRDQLAELLADYRAAGIQNILALRGDAPEGMDRFQA
TEGGFSHATDLIAFLREQGDFSIACATYPEGHPESTGGVADDIRYLKMKQDNGADCAITQ
YFFDNEAFFRFRDSCDKAGITMPIIPGIMPIGNFDQIVRFSSMCGASIPAWLHEKMAPIR
EDLDAVAKLGIELAASQCRELLEQGAAGLHFYTLNKSAATIAIHGKIRDYL
>A0A645GU83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MAEYLIANQIQEVLEITGDPPQDMRWKIYPTTSIDVIRKFKAEIPGIKVYAGIDQYRESM
RKEADYIKRKIQAGADGFFTQPFFDLRLMEIYTEILQGQEVYWGISPVTSEKSLHYWETK
NNVVFPASFQPNLEWNIAFARQALDFTRQTQANIYFMPIRTNVDQYLQGIFADK
>A0A1B7VSX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabaena sp. WA113|TrEMBL
MPDTQSYSAFNNFRKASLTGEFLITAEVAPPKGGDMTHTIKMAATLKGRVHAVNITDGSR
AVMRMSSLVASAILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPQAKAVFDLEAVRLLQLIRNMNQGIDFNEKPLTDGKLDLFAGAAVDPQSRSWSGLQS
RFEKKIAAGAQFFQSQLITDFEILEKFMDKIACGYNKPVLAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEEGMKIAAEQVQMARGLCQGVHIMAVKREDLIAPILDLAGV
GKVS
>A0A656G3I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. mori str. 301020|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A3S8Z9D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flaviflexus salsibiostraticola|TrEMBL
MSSIFGGPLVSFELMPPRNPDNAPKFWGTVKRLMDFRPDFVSVTYGAGGRNADTAHEVIA
QLVRHTPVQPIAHFTCVGMSRAGVYEELAKYLRTGVRTFLALRGDPPVGDPDWSPAPDSL
QSAVELVAAIREIEEKTCAESPSAALRKAFRPLTIAVAAFPNGNPAAGTNVDDEVNRLLV
KQAAGASFAITQLYWDPSVYVDFVARSRRAGVHIPIVPGILPPVESRRLHRTAELTGIVA
PRGLLESMEEAERADAESGESTHAYDIGVSYAAWLARQALEAGAPGLHLYTFNRAEPSLD
VLRRLGITHDEPDDHALRPVPTASAVSLSPQYQI
>A0A3R9FYD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNHISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2K4ZDN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetatifactor muris|TrEMBL
MLQDMFEQKRTLSFEVFPPKKDGEFDAAFDVLNALGKLEPDFISVTYGAGGSRSGKTVEL
ASYIQNTLGIDTIAHMTCVGSKKEDLLGIAEKLKETNIDYVLALRGDRPGDMTDEQYASR
DFAHASDMMQFLQENTQLHLAGACYPEKHYESFSMESDLNNLLKKQKAGAEFFISQLFFD
NDYFYSFLEKADKKGITIPICAGVMPIVTARQIGTTVKLSGSSVPKALSDLFATYGDNRQ
EMRKAGIDYAIRQIRDLQENGVSNIHIYTMNKPKMAGEIVNAIYR
>A0A2T1KE17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter halophilus|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRDQLAEVNPDFFSVTFGAGGSTRDRTIETV
LSLHKQGISTAPHLSCVGGTRTEIGELLDLYKKHGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARSAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRQ
FGEEVVTRMCEKLLQAGAPGLHFYTLNQAEPSLSIWKNLGITDREKIAF
>A0A0V0TNX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella murrelli|TrEMBL
MFCDDIVYNQLYRVAKVGNPSQQTDFGVYFEEDSFLSLMASLEAVELKATRHDLNSAAKK
STDEIYRPLIDRIKENISSGRRFFSLEFFPPHTTEGLINLLKRVDIFANSQPLFVDVTWV
MRSDPASEKVTSSSSLADCILNFCLLDTMLHITSVQYDEKTVLFNLERAKKIGIRNILAL
RGDISDDANVTTTDFQYACQLVRFIRSHYGDYFTICVAEDLLNLKAKVDAGADFIITQLF
FNEMHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSKIVIPDSVLTTLESIKEN
AEAVRNFGISYAVQLCRKLLNREHHVVPGLHFYTLNQEKSILEQIGFWKKAPVRMFPWKK
HTVHSVRCREAVRPIYWTARPKSYLCRTRDWKQFPHSRWGDVGNPAFGDLKHYLFSCIDQ
MDDSCALDMWDKELSTLEHVRDIFCNFIARTPNRHGHSVRRLPWNENHLDPAADVLKNEL
IYYNSNGILTINCQAAVNGLPSSDPIFGWGEANGYIYQKVNARCILISLGYLEFFASSTC
TTILLNHVQNFPSINYHAINFDGSFETFNYDEDATVALTWGVFVGQEIVQPTVANAASFR
VWKVVAQLSFIQLFLFVFEQDEAFDLWQRWAGLYESGSIGRKLLQRIHDDYRLITLIDND
YPQPCSLSALLRAVISDYIGGKNLTTDDDRLACKKKQCVRECVRACAYVENSGRLALRAS
KHGITAEKEEEEEEEAIIE
>A0A0U5DGN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAATKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIAFI
RAEHGDAFHIEVGAYPETHPQASDSLADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLRLLQG
>A0A502Y7K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-7-1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFADMGVKRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A261S3S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella genomosp. 10|TrEMBL
MTDTKTPALSLEFFPPRDIAAQERLVRAAKQMLAMHPRYVSVTFGAGGSTREGTAGTVRT
MRNLGVPAAPHLSCVGASREDLRGILRAYREEGVKQVVALRGDLPSGMGGDAGELRYARD
LVAFIREETGDWFHIEVAAYPETHPQAESPSADLDHFVDKVRAGADSAITQYFFNPDAYF
DFVDRARAKGVDVPIVPGIMPITNHSQLLRFSQMCGAEIPRWIRMRLAEFGDDKASIRSF
GVDVVSGLCQRLLDQGAPGLHFYTLNNAEAPMGIWKNLDL
>A0A2M7U6K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium CG_4_10_14_0_2_um_filter_48_9|TrEMBL
MKVIEYLEKATETLISFEIIPPMRGRSAQEVYTILDQLIEFEPPFIDVTSHAADAYYVEQ
KDGSFKRYIKRKRPGTLGLCAGIKYRYKIEAVPHLLCRGFTREETEDMLIELNYLGIENL
LAVRGDDPNYQKAINPDRSKNNYAIDLVRQVADMNRGRFQDDILDSAQTDFCIGVGGYPE
KHEESPNLEADIRHLKEKIDAGAHYAVTQMFFDNQYFFDFEKKCRDAGITVPIIPGLKLL
TKPYQMKSLPSNFHVNIPDTLVAAMTAADSETEAQQIGVEYLKKQAGELINAGVSCLHFY
VMNDVHLVKEVVRSLK
>A0A5D0TEA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. WP24|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTPEGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVAHPEGVRYAEELVQLIRGAGDFSVGVAAFPYKHPRSPDVTSDTEHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCATPILAGVMPVTRMATIERSVQLSGAPF
PPALAERFARVADDPEAVRRLGVEQASEMCARLLDEGVPGIHFITLNRSTATREVWQNLR
VQART
>A0A7K2ZBU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID2119|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFSQLSNATV
PEPLKERIIEAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A7C6KT66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MGKTRKTLKERLQAKEFIVTWELVPGRGAWEPCQEKVLKLAEQAAKGNLVHAVSLTDNPG
GHIGIKPEVIGKEIADMGLETIIHLTCKDKNRSQLESQLYALERLGLHNILVLTGDYVVE
GSWGTPKPVFDLDSTQLLQLITAMKRGLEAPSSKQTVFQPANFCVGAVVSPFKATEAEVK
LQYSKLRKKIANGAEFIVSQVGYDARKYHELLLVARQNNWQIPLFGNIFLLTYQAAKLMN
QQKFPGCVVTDKLLAEVELERASADKGAQKRLERAAKLYAVLKRMGYQGVHIGGLDVAYE
QVAYIINRGEEYLANWQELIREFVYPQDQGYYLFAPDEKTGLNKEEMAPPPAKDDTKQEL
RYKISRRFHKLFFVPEKNLFPAMRSLSAKIEGTRLEKGFHALEHSLKAALYNCQDCGDCA
LIDTAYVCPMGDCPKNQRNGPCGGSYYGWCEVYPGQKKCIWVRAFANLKKYREEENLNSY
QVNPCNWKLKNTSSWLNFYLGKDHSAERLKISHPKKKGD
>A0A7X8QF05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MEERSFRNVIQDKNVFTVSWELVPGRGSWEESQEKTLRLAEQAAKGKKVHAVSLTDNPGG
NIAIPPEAIGKDIQKLGLDTIIHVTCKDRNRSQLESQLYALERCGLHNILALTGDYDLGG
ADGRAKPVFDLDSTQLLELIKKLNAGMEYQTMKGKATLKSCHFFAGAAVSPFKATKAEQM
LQYYKLKKKIEQGAQFIITQVGYDVRKFEELILYVQKMGWEIPLIGDIYILSYGAARFMN
QNKVPGCVVTDKLLRELDEERNSPDKGKEAMLKRAAKQYAVLKGLGYKGVHLGGMNINYE
QIEYIISYGEELSRNWQDYVREFDFPQKNGFYLFGRDPKTGLNNPALPPPKYQTDSKTEL
NYKVSRLLHKMFFEPGKKFFAPMQTLTCKIQGGALEKGLHGMEYFIKRVMYNCQDCGDCA
LFDLAYICPMGDCPKNQRNGPCAGSYQGFCEVYPGQKKCAWVRAYERLHKYGEESCLGDY
YTSPCNWELKNTSSWVNYYLGKDHSAPRLGIKPKVKDKN
>D8IUM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum seropedicae (strain SmR1)|TrEMBL
MSTSTHNFSIEFFPPKTAEGAEKLRATRARLAALQPKYFSVTFGAGGSTQQGTRDTVLEI
VSEGHEAAPHLSCIGSSRASLRAILEDYRANGIKRLVALRGDLPSGYGAMDQASSEFRYA
NELVEFVRAETGDWFHIEVAAYPEMHPQARSPQDDAQNFARKVKAGANSAITQYFYNADA
YFRFVDEAARLGATVPVIAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTESIR
AFGLDVVTQLCERLLAGGAPGLHFYSLNQAGPTQAIWQQLVK
>A0A1F9DGU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_47_11|TrEMBL
MENNRFKEALLERKQFIYTLELVPGRGSRGKTQDEVIQIAEKAAKAKLVHALSITDNPGG
HPALSPNMLGLEISRLGIDPLIHFTCKDKNRNQIESILYSLDRNGLSNLLAMTGDFPLYG
FEGKAKPVFDLDSVQLIHLISEMNQGLDIDGKAPGGGVRLPPTHFFKGCNVSPFKKYESE
VMAQYYKLYKKAKAGADFVITQLGFDTRKFDEVLRFMRQNAIRVPILGNVYILNRAVARV
MNQGGVPGCVVTDDLYRIYEEEAKAPDKGKTARLIRAAKLIAVLKGIGYDGVHIGGPNLT
YEDVESVIHKSEEFSSNWEEWGREFSFPQKGGFYLFEKDPKTGLNTDLPVKERSHPRKAI
GHMIMRFFHRLAFTPEAPLYKPARWFFKKIDGTRFEGPITELEYWIKFVSSRCRRCGDCT
LLEVAFLCPQSQCPKYLFNGQCGGSLEGWCEVFPGKKRCIYVRAYDRLKPYGEEESLKQD
YIPPRNWALDQISSWANYFLGRDHHGQK
>A0A117LHH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 66_15|TrEMBL
MSRLRELLESGEFVVTGEVAPPRGTDLADMHASVDLLAPHCHALNVTDNQGASLHLSSLA
ASRAIMERGIEPIFQQTCRDRNRLALQSDLLAAWSLGLENVLVVTGDDPRAGDHPHAKGV
FDLDSTQLASIALGMNEGRDMMGRDLKGGTDFYIGAAMFPEAEPWDVQLARIEQKVAAGV
RFFQTQAIFDMEKLQRAVDAVRPLGVKVIAGVLVIRSPRVVDFVNRNLAGLMVPDHVADR
IRSAPDPAEEAVRLAAEQVRDIREIADGVHVMPLGLDTEVGRILDGSG
>A0A520MNU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR92 clade bacterium|TrEMBL
MPLSTNQEKQALIDLMGKTTLEVTPGGAAKVSDFSQILRAGCTVYVTFLQGSDFGDTMAT
VRRLKSEGYNPVPHFAARSIPSAQMLEESLAALQSEGITEGLLIGGGVDKPVGEFNASID
VLRTGLFEKYGFTKLGLAGHPEGSPDISDADCALAIQQKNDYAKESAMSLYLATQFVFEA
APVLAWEKKIREQGNMLPVYVGIPGIATIKTLMRHAQHCGVGPSMRFLTRNPLDMIKLGL
KDSVLGKFVNAPSSEPSELLRDLIEGINADPDCLIQQCHLYPLGGLKKSAEWMYKIQDGH
FEISAKGFTTT
>X5MC11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Phaeomarinobacter ectocarpi|TrEMBL
MATRTDDQSSENPIEVSFEFFPPKTEKMEQTLWASIEKLAPLNPRFVSVTYGAGGSTRER
THSTVKRIVDETSLKPAAHLTCVEATREEIDGVIQDYWDAGIRHIVALRGDPPSGIGEKY
VPFEGGYANAAELAAGISKIAPFEISVGCYPEKHPESASFDADIDLLKAKIDGGATRAIS
QFFVETDNFLRFVDRARSAGIDIPIVPGIMPVGNVAGYLRMSAATGTSVPDWFKERFDGL
DDDPETRQLVALSVAAEQVQKLADQGIQQFHLYTLNRAETAFALCHILGVRPDKSLAA
>N9NC78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 3862|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A0E9MXB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavihumibacter petaseus NBRC 106054|TrEMBL
MKVIDHINQANKTLVSFEILPPLKGKGISAIYNHLDPLMEFKPAFINVTYHRSETMFKKQ
ADGSFTKIEVRKRPGTVGICAAIMQHYNVDPVPHLICGGFSKEETENALIDLAFLGIDNV
LVLRGDAARNEASFEAEPGGHRYAIDLLRQVVDINSGIYLEEEVKDHGNARFCIGVAGYP
EKHFESPNRNTDISYLKAKVDAGAEYVVTQMFFDNRKYFEYVDMCREAGITVPILPGLKP
ITSKKQMNILPRIFHVDLPTDLSTAIAKCKSDEEVEIVGTEWLLQQSRELKAAGVPVLHY
YTLGKPKVIWNVVKEIV
>A0A3N7GHP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parapedobacter sp|TrEMBL
MKITEHIKNANGKPLFSFELLPPMKGQSIASIYNTIDALMEFKPPFIDVTYHREDYIYKQ
HPHGLLERIAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLHFLGIDN
VLVLRGDARKADKDFVPTPGGHAYATDLLQHVKDMNGGKYLHEDIENSECTDFCVGVAGY
PEKHFEAPNFETDFRYLKKKVEMGADFIVTQMFFDNSKYKAFVERCRADGINVPIIPGLK
PITSAKQLITLPKIFHIDIPVELSEAIGACKTAQQVKEVGIEWMVQQCKELVEFGAPVLH
FYTMGNPAPTRQIVEQVF
>A0A540LBD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malus baccata|TrEMBL
MKVIEKIQESMVDEKKVVFSFEFFPPKTKDGVESLLERLDRMVAHGPAFCDITWGAGGST
ADLTLDIANKMQNLICVETMMHLTCTNMPVDKIDHALQTIKFNGLQNVLALRGDPPHGQD
KFVQIQGGFACALDLVTHIRAKYGDYFGVTVAGYPEAHPDAIAADGLASPEAYQSDLVYL
KRKVDAGADFIVTQLFYDTDVFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPAEVTAALEPIKDNEEAVRLYGIHLGTEMCKKILAHGIRTLHLYTLNMEKSALAILTN
LGLIEESKISRLLPWRRPANVFRVKEDVRPIFWANRPKSYISRTVGWDMYPHGRWGDSGN
PSYGALTDYQFMRPRARDKKLVEEWVVPLKSIEDIYEKFKKFCLGKLRSSPWSELDGLQP
ETRIINELLGKINTKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSKEKL
DALVEKCKALPSLTYMAVNKDGSWISNIGQTDVNAVTWGVFPAREIIQPTVVDPTSFIVW
KDEAFEIWSRGWARLYSEGDSSRKLLEEVQSSYFLVSLVDNDYIHGDVFAVFADF
>A0A0T6YKA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. Sb3|TrEMBL
MSPDINPFDPGAPLEPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGVG
PMASAKTARWIRSNVPGIHIPDSVITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGIHV
MAYRQEEYVAEIVHESGVLKGRRPWKHETLPEDALVAERLEHIREGKEENQQEMAEAAAH
HPH
>A0A6L7U7K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineaceae bacterium SB0661_bin_34|TrEMBL
MVPFLEALQAGPLLADGGMGTLLLAHGARVDQNLEELCLTEPDRVRELQLAYARAGADIL
LTHTFGAQSLRLAEHGLDSQVVAINRAAARIARDVRESSGRDIFIAGDIGPLGRALAPRG
PISTEQARTAFREQAAALLEGGVDLFCVETMTDVAELRQAVLAIRELSDLPVLASLTFSA
DGETLFGLDAAAAAEMLTDLPIDILGANCAVGPTALLDVLATLRAARPGIWLSAMPNAGL
PTRVDGRFQYEAGPEYFAAMVPEFLARGARIVGGCCGTTPAHIRAMRQALDSIDSDHEGE
PVHLETEPSVEWGVRVSETGGPHAADPVSASGLLAKIRAGEFVVSVEVDPPRGLNPERQL
AGARLAKERGADAINVADSPMARVRMGALALSTLIENRVGIETILHFTTRDRSLMGLQAD
LLGAHALGLRNILALTGDPPSLGESQNSSPVYDTDSVGLVQILHQFNRGQDLQGKEMGQH
SSFAIAVACDPTRPDLELETERLTRKLQHGADFIMTQPIYDPMVWIRFADLYATRYGPIP
APVLIGILPLQSFRHASFLHHEVPGITLTPTALNTMKEAGKQGRQAGVVMAQDLLLGLID
APHVQGVYLMPSFGRYETACRVLDVLDRTPAKEAA
>A0A7W7AET0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium taihuense|TrEMBL
MNTSYDQLREARTALDTPLFAGLPGDINVSFEFFPPKTDALMAQLWDVVETLGPLQPKFV
SVTYGAGGSTRDRTHGTVARIIREAKLPAAAHLTCVDATKAEIREVAESYWEAGARHIVA
LRGDMGAPGVPFTPHPDGYANAAELVAGLKEIAPFEISVAAYPESHPDSPSSQADVDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAAACGAA
IPAWMDGLFEGLDTHPASRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPKAPALEKAA
>A0A7X9HFJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MNIITRLQQKKPLLSFEVFPPKTPIGEENLFHELRVMVSFKPDFISVTYGAGGSTREKTL
EIATRIKSTFSIEPLIHFTCVGQSKDDIASYLNYVQSLGFNNILALRGDPPAGQHKFTPH
PEGFKYASELVEFIRTMDHFTIGVAGYPEGHIEAPDLDTDIQNLKKKVDAGADFIITQLF
FNNDKFYTFMDKTAKAGISIPIIPGIMPLTNMAQLQKVTTMCNPDMPVALLQELEKCTLP
DDMCKVGIEFTINQCKELQSYGVPGFHFYPLNKSAAVKSILDEFWHG
>A0A7V8IGK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium fontis|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLRDIARDYWQSGIRHIVALRGD
LPPEGGKPDMYAADLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFSTMTNVRVPNWMTAMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVTR
>A0A496QMA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
FAVTAELGPPQTANADIIRKKTFNFKGYVDAVNITDNQTAIVRMSSIATAVLLLREGFEP
VIQMTCRDRNRIAIQSDILGAAALNIKNILCLSGDHQKFGNHRGAKNVYDIDSIQLLSVV
RAMRDEARFANGEEIKTPPKMFIGAAANPFADPFRFRVVRLAKKIEAGADFIQTQAVFDV
PRFGEYMCERAGFLPRPVYK
>A0A660SLF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MSGNYNMFHVEVLPPKQDAEDLEVRLDRFAARYKRVLDAGYCACITDNAMGNMSFQGSEI
IEEYDLPVDGDNVMIHLNTFHSKKVLDDILKSCIDRGIEYLLVISGDGNVRFPKLKPSDL
GLQGVSSVTAVELLQYINREYSGVFHNGVAFNPYEPEEEEHEKMMKKIDAGAEFVITQPI
IDENTIVDKLIAEIDLPVMVEAWMSKKLHLLSDCVGYDIPEDTEYDPIESLKKLQSNYPS
GGVYLAMMNYKRQFNLLSEIGRA
>A0A4Q5M778|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. OPT22|TrEMBL
MAFHHAQHSSLLNQNLAEHNGDINVSFEFFPPASSEMEQMLWKSILRLSPLDPKFVSVTY
GALSGVRDRTHNVIERIQNETSLVAAPHLTLIDADDCELKELAKQYWNSGIDHIVALRGD
IPEGYDNPQRYASDLVALLRSVADFDISVAAYPEVHPDALNAQSDLVNLKRKVEAGASRA
ITQFFFDIETYLRFRDRCAAAGIEVEIVPGILPVTNFQQLKKFAGITNVSIPDWLHHQFS
GLDNDPETRQLVGANIAIDMVKVLAREGVKDFHFYTLNRPELTYAICHTLGIRPQKVA
>A0A369A2Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schleiferia thermophila|TrEMBL
MKIIDIIKNTQKTLFTFEILPPLKGDNIFDVYGNIDPLMEFNPPFINVTYHREETVLKPL
PNGLYQKKVIRKRPGTVGLCAAIMHRYKVEAVPHLLCGGFTREETENVLIELDFLGIQNV
LALRGDSQKGQRYFIPEPDGNHYAYQLVEQIQNLNKGIYLDEEIENNTPTNFCIGVAGYP
EKHFEAPNLHIDIQNLKRKVDAGADYIITQLFFDNQKYFDFVDKCRNAGIGVPIIPGLKP
LSTKKQLSLIPHMFHVDIPDELSIEILKAKDNRAVRQIGIEWTIQQSKELIKAGVPVLHY
YSMGKSDNIYQVAKSVF
>A0A4U3FSA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plantibacter flavus|TrEMBL
MITTEPACPGRTPFSFELYPPKTLDGGLALARTVEHLAAAGPEFISVTFGAGGSSRTASL
DVLRSIRTSTSVDPMAHLTCVGSTHAQASRLIKDFLDAGVHSFLALRGDPPAGAVEGDAF
LGDLGSAAELVQLIGRVSAEHEPYAEGSLVGLPGAVQLGRRHRPRIAVAAFPNGHPRSRS
TTQDLDTLLAKQAAGATLAITQLFFHADDYLAFAERARRHGVTMPILPGVMPITSPARLR
RVLELSGEALPSDLAIALEVEPDEAGRIDIGIDYSARLIRDVVAGGAPGVHLYAFNQHRT
VLDVLHRAGIPVQGDRPVRHPIPDPLTSKDAR
>A0A0R2VE71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilales bacterium BACL14 MAG-120920-bin58|TrEMBL
MATLPPISFEFFPPRNEEGIQSLELVVKNLNLFDPDFYSVTFGAGGSTKEKTLETVLKIK
ELGSTAVPHISCISSSKQEISQVLKAYQSHNINQIVALRGDNPSGAVNYGDFKYANELVN
FIREETGDHFLIEVAAYPEFHPEALSAQDDMDNFQRKIDAGATGAITQFFFNVDSYFKFM
EECHRRSIAIPVVPGIMPIYNVKQLSRFSANCGSEIPRWLRMRLEDYGDDLESLRSFGVD
VITELCETLTQYGVPSIHFYTLNQSGIITKIINNLKS
>V0VHU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 908519|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1F4CYB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_68_19|TrEMBL
MRAPMTSERRAASELQAKLRSGEFVVTAEITPPVSTDPAEFLRRALPLKGLATAVNVTDG
AGAKVHLSGLAAAHFLVQSGIEPIFQITCRDRNRLALQADLLGAASLGIHNILVLAGDDP
KLGDQPQAKPVYDLDSRGLIAMAHEMRTRGKLPSGTEIQGKFNLVIGAAELPVDPQPGWE
PKGLAAKIAAGADFVQTQFCMDLEVVRRYAARLLERAIKLPILIGVAPIPSARSARWMRD
KLYGTRIPDEYVLRLEKATDPRREGRKICVEVLQGLAEIPGIAGAHVMAPMNFAEIPATI
EQSGVLGRKRRAAA
>A0A5P9NQ31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halioglobus maricola|TrEMBL
MAKPRISFEYFPPKTDTGKDKLLSETTPALNELNPEFFSVTYGAGGTTRDTTLGVVSTMR
EAGIDVAPHISFGGDDEDTMAELLQTYKERGIKRLVALRGDMPSGMGAAMQLVYANELVE
FVRDKTGDHFNIEVAAYPEIHPESKNYDSDVQFLKKKLDAGANSAITQYFYNVEAYFYYL
DQCMAAGIDKPIYAGIMPITNYQNLARFSRNCGAEIPRWICQKMEGYGDDQESIRQFGLE
VVTQLCQTLMDSGCPGIHFYTMNQVEPTRAIYNSLGL
>A0A8F9UN67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya zeae|TrEMBL
MSFFHANHQEALNQNLAELQGRINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPLGGGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPIASA
>A0A418JKY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus hyicus|TrEMBL
MSRLLNTLKDSILVADGAMGTILYSEGLDTCPEAYNLTHPEKVEHIHRSYIQAGADIIQT
NTYGANFEKLKAFGLEHKVRDIHHAAIAIAKRAAKADTFILGTVGGFRGLKQGDFTLPAI
QYHTEIQIDCLVQGGVDGLLFETYYDLEELLAVIQATRQKYNIPIIAQLTASNTNYLRDG
TVINDALQQIIHAGANIVGLNCHHGPHHMKNSFSHIELPHQAYLSCYPNASLLDIENNNF
KYSNNASYFGEVAEQLIHEGVRIIGGCCGTTPEHIHHIKTSIRGLKPVTHKKVIPIHKKR
ESTTPHATKLNLKERVTQQPTIIVELDTPKHLDTDRFFKNIAALDRANIDAVTLADNSLA
TVRISNLAAASLIKQKYTIEPLVHITCRDRNLIGLQSHLLGLALLGINEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNEGINTDGDALKRRTNFNIAGAFDPHVRNIDAAVRK
LETKLTSGMHYFITQPVFTKEKIVEIYEATKHLNVPIFIGIMPITSYNNALFLHNEVPGI
KMTDDVLEGFKAVAGDKLATYELSISICKSLIETVHQYFNGLYLITPFERVDYALELAAY
SKSITSTNQEVIL
>A0A850J2M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. 323S2|TrEMBL
MTDLTTPARAEGQDGHLQNGHLSSKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFV
SVTYGAGGSTRERTHSTITRILRETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVG
LRGDPAGGIGTPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDT
LKAKVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAG
TSVPDWLAEKFDGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISH
LLGIRAKSAQKAA
>A0A6H3JNV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMB3-1-2|TrEMBL
MTATPTTPPTDPDCRSSIPFSFELYPPKTDAATMALHATIDALAAARPKFISVTYGASGS
SRTSSLDVLRYIRRATIVDPMAHLTCVGSSHAEASSLIREFLDAGVSSFLALRGDPPEGL
TENDAFLGDLHSAGELVQLIHRVQAERVPYQETPIPGLPRARAVKTEREHVRIAVAAFPN
GHPRSRSTAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPV
TSPGRLRRILELSGEELPAELSIQLEVEPTLEGQREIGVSHAAALAEKLIAGGAPGLHLY
AFNQHETVLAVLDRAGALAPAQPVVSAHNPPPTHPSTSPADTRAGIHSTKDHY
>A0A7M1SUU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruania alkalisoli|TrEMBL
MTTSLALSTVGGCPKRMTYGPCGGVAADGTCEVTPEPCPFVTEATVPWPGPGPATTPPTA
EGLQILDLLQRRPIVVAGMPARAMDVASVEACGRQLAGRVDAVLAGDSGRARVQFPPTYR
AELIRRAGLRAWPGLNCRDRNRVALEGELAGLAAVGAAGVHCVTGDHPAGGHRPDAQPVF
DLESTELVGLARKHGLLVSVAESPASPPVHRRAERLAEKVRAGAQLCLTQYCGGADEVRA
FVAAMRQAGADVPLLPGVPVVLDVPSAELLASFAAAVLPAGYVESVLTASDPFRAGVEAA
IRYGEELLAVAGVAGVVVAGAAEHGTEEETSAAIGQISAALGGGS
>F6G658|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia solanacearum (strain Po82)|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRGILDTYRANGIRRLVALRGDLPSGMGEIGEFRFANELVEF
IRKEMNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>E6SH71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermaerobacter marianensis (strain ATCC 700841 / DSM 12885 / JCM 10246 / 7p75a)|TrEMBL
MTHSSRQRGSTAPPPGHPHPDEPAGFGPAVPAGEGAGRLFPPFPMLADGDPSWSLAAGIG
EPGQTARPAAARTAAAAAAARAAPTPPEAGPPGEVLAEVAWWPLRRPRAVEAAHLEAIRA
GARLVRTHTRWASPAWLDRVPRTRVEQINLWAAKLARSAREVAGEPCLVAGLLGPLPAAP
AGAAADGWEEALAAYRTQVAGLLAGGVDLFWIEARTAAEAAAALAAVREACRLPAGLVWI
PGGPGSGGDGTGTGDPGELEAHTPQGFVGQLVKVVRAAGSPDALGVAVTGGPAEAARWLG
GLRRAGWAGPLWASLGTAGEAAADREGWEALRTLGVGWIAGTGPWSPAGLAALGRRAGLV
PATLGDAQDTPAHPATPVPPRPARPHTVQPVPAPPATHGAPPHPAVAGPLAGSHAPRVSG
APATPPLLPGAGEPAPLREKLGRRFVISVELDPPRGPVTTKFVADARTVAAAGADAVNVG
DSPMARPRMAALAGAYLVRAAAGIEAIMHCTTRDRNLMALQADLLAAHALGVRNVLALTG
DHPKLGTSGASPVYDVDSIGLLEVLAALRRGEDPQGNPLGAPADFTVACALSPNADDLDR
ELDRFRRKLAVGVVDFVMTQPLYEIEPLERVLDRLGGCPVPILMGVMPLHSGRHAHYLHH
QVPGISIPAPVREALDRAGDRGLEVGLELAEAVVEAARPYIAGVYVVVSYGKAEPVAEFV
RRLRTRFDQPLPGPQGAVTVAGPPSGTATAAGSSAPVAAVQAPVTSGPMPVSRQGEVRPH
AG
>A0A1F8THL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_19FT_COMBO_62_14|TrEMBL
MDVREQLESWLARGRPILADGAMGTMLHMRGVGFDTCFDELNSTQPALVEGIHRAYLAAG
AQIIETNTFGANHFKLGAHGLEARAGEINAAACEVARRAIRSTGSEALVAGSIGPLGVRL
APYGRVKPAQAYTAFREQITALVDAGADLLVIETHSDLAEVGEAVRAARAVTAIPIIASL
TFTRDDRTLLGELPARAAAALAKMEIDFVGANCSGGPAQLLRVLQQMRRAAPELRFSVMP
NAGWPERVHGRIMYPATPGYFADYARAFCQAGASIVGGCCGTTPEHIAAMRLALSDEEGP
CLESEPLDSAQTVLPVVSSIPAPTQFASRLAERRFLISVEMDPPRGLAVQKILAGAHLLA
EAGADVINVADSPMARMRMSPWAICQLIQRELGVESVLHFPTRGRNMLRVQGDLLAAHAL
GVRNVFIVMGDPTAIGDYPEALDNFDIVPSGLIRLIKHGFNAGVDQAGADIGEATSFFVG
CALNLGAADADQEMSVLQRKIHAGADFALTQPVFDAELAAEFISRFQSRYGPLTLPILAG
ILPLYNDRHVAFLHNEVPGIQIPDAIRRTITSAGENAPEAGVKLAVELLQALSGVVQGAY
IMPALGRYDLAAEVIEHARSVTLRR
>A0A4W4E2N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Electrophorus electricus|TrEMBL
MVNQRADPCRQSCRSDSSGTSNSGESSKESSRCSTPVLDADRTDRLREKMRRRIESGDRW
FSLEFFPPRTTSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCKQTKEKITDHLTKAKRLGLKNIMALRGDPIGADWEEEVGGFSYATDLV
KHIRSEFDHYFDICVAGYPTGHPEAENYKADLLHLKEKVDAGADFIVTQLFFRAETFLTF
VKDCRAIGINCPILPGIFPLQGYHSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNFGV
QHAVEICKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAISAHPKRKV
EDVRPIFWATRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPREALLK
MWGEELTSEQSVYEVFTNYITAQPNHNGHKVMCLPWNDDPLAPETNMLKEDLEKVNRRGV
LTINSQPNINGKPSSDPVVGWGPPGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYH
IVNVQGKNITNAPDMQPNAVTWGIFPGREIIQPTVVDPVSYMYWKDEAFTLWIEQWGKLY
EAESPSQMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIDSMFELIDAPPEPFDQEAE
>A0A414CMS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKREAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFAHQPNFEVN
>A0A1W2M2T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis keratiniphila subsp. keratiniphila|TrEMBL
MDLVRRIDRAAGEFLLFALTPPRLATAQERVQQIADATMARLRPLNLDGLILYDIDDEAA
RNPARRPFPFVPTHDPANYLADNFTNWRTPVIVYRAVGKYTPSELRTWLAAQDPARVMTV
LVGASSSKIDTMTSLADAQALRRDVNPGLSLGGVAIPERHSRRDDEHLRLLAKQDAGCRF
FVTQVVYDVNAAKNLVSDYHYECVARGRAPVPIVFTFSVCGSLKTLDFLRWLGVDVPRWI
ENDLKHAADTLEASYQLALAAATELMTYCRGLGVPFGINVESVSIRREEIEASVRLAERL
RAEIKG
>A0A1G4B266|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum orchidophilum|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTAMGLSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKNE
YRDTEDSETDDAEDFVWAADLVKYIRKNYGDYFCIGVAAYPEGHADESHPQGQSFEHDLP
YLVDKVRAGADFIMTQLFFDIKAYESFENTLKEHPSGAFKDIILLPGLMPIQSYQMIKRT
TKLSHAKIPDNLMARLDAAKGDDEKVKQVGVDILSELVEQVKEIKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDPKTEDEEAIIDDGPGVPVSVPAVQLNGLSPVPHATRTLSGGRR
PSSMGSDPHNRIIVSGSASNPAYETTTAGLMVSEPVNTRANTLAISEGVGAVGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHMSVTQAIRLWGTPKTVQDINNIFIRHIKGQLNAIP
WSEEELLPESNIIQQELLELNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVE
LFIPSSDWAGLVARLNEITDNTICFYAANGAGDFVSSDASGGLVLEGTEASTNAVTWGVF
PGKEIITPTIIEEVSFRAWAEEAFKIWGEWAQVYGKGSESEVLLERISSEYWLVNIIHHD
YVERGALWKLLSGEKEI
>A0A1Y5FG43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium 54_18_T64|TrEMBL
MTKDWLLSFEFFPPKTQPGAEKLARTRETLARLAPEYFSVTYGAGGSTRDNTRDVVLETR
AAGLDAMPHLSFAFGDDDANAIKTLLETYRQAGVSRLLALRGDLPSDPESTRKPIHANEL
VAFIREHFGEQFNLQVAAYPEIHPDAKSYQDDIHWLGEKFKAGADGAITQYFFNIDAYWY
FLDQAAKAGIDKPIVPGIMPITNFTSLARFSAGCGAEIPRWMAKKLEQYGDDQASIIAFG
TDVITQLCERLLEGGVPGLHFYTMNQAQPSIDILSRLGVSAGQS
>A0A5H8HE56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella blockley|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1S0ZDQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Saintpaul|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J2SWI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila hydei|TrEMBL
MCVNGTRNQTAAALLLRHVRTIAQHRVSQLIGRNQLLARSARVNIELAMHALEPNGTRRF
GGDLSKRLLDCFQFTPEQLAGRGEQPYISDLVSDKVARGEFFYGIEISAQSGGRLTCVDF
NRFQPILPALISIVWLCHYWDVTPMERVDSLQMIRHLEPYIPAMPNFSIYMMTKERIDEF
LALNFKNLLAVRGNRSDDSQFYTYGYQLVEHARRARKSNLTIAIPGYPLCHVGSDRRSSD
MLIHLEHLKQKIDNGADLIMTQMCYTAEMIVEYLRCVRNEGIVTPIMVGVGVPESLKSYQ
IMQSITGIELPAEERAELRKVESDNAKVREYFVQLALGVIQKVLDAKLDVYGIQFYAMNR
FGGVYEVLKRLRQMGILKETRREACGDS
>A0A6J1JBG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cucurbita maxima|TrEMBL
MKVIDKIRAATTGDDARVVFSFEYFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGS
TADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQ
DKFVQIEGGFACALDLVKHIREKYGDYFGITVAGYPEAHPDVIGSNGVATLEGYQSDLAY
LKRKFDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIIPGIMPINNYKGFIRMTEFCK
TKVPDEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILM
SLGLIEESKISRSLPWRRPTNIFRVHEDVRPIFWANRPKSYISRTIGWDQYPHGRWTDSR
NPSYGALTDYQFMRPRARDKKLLEEWALPLNSIEDVYEKFMKYCLGKLRSSPWSELDGLQ
AETRIISEQLGKINMKGLLTINSQPSVNGERSDSPSVGWGGSGGYVYQKAYIEFFCSKEK
LDAVVDKCRALPSLTYMAVNKEGVWVSNITQKDVNAVTWGVFPAKEIIQPTVVDPASFHV
WKDEAFELWSRGWASLYPEGDPSRKLLEEIQISYYLVSLVDNDYVNSNIFAALEDF
>A0A2M9XKL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira kmetyi|TrEMBL
MKKISEIYGSAKGPVYSFEFLPPKTPDGEAKLMETVKELSRLNPDFVTVTYGAGGSTRDK
TVQISSEISKNYSFPTASHFTCVGANREQILETLKGIRSAGIVNLMALRGDPPRGEGEFK
KTEGGFANATELISFIRSEKMDFCIGGGCYPEKHPNAKTLEEDVRNLKLKVEAGTDFLVS
QLFFVNSIFENFLNLVRKVGITIPVIPGIMPITSFSQIERFRSLAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFTVKQCRELLEMGAPGIHLYTLNQSHASYDIVRELKG
>A0A3C1QCE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPRRLKDVLAQGQFAVTVEYNPPKGTNLTHVVESAKALVGRVHGVNVTDNTAAIVRA
GSLPVCRVLYELGHDPVMQLTCRDRNRIAMQSDLMGAHILGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVTGLNNGKDYAGNKLDGSTAFTIGGAVTPEADPLGPMLVKFEVKV
RAGAEFFQTQAIYQPEQFKKFMEAVRPFKVKVLAGILLLRSAKMAEFMNANIPGVCVPQD
MIDEMRAAGDKRALDVGVEIAVRTIKAVRPYCDGVHIMAIKSTERLPEILTKAELG
>A0A0C5CSM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weizmannia coagulans|TrEMBL
MDLLETLKNRILVADGAMGTLLYAYGADTCYESFNLTHPEDIHAIHRAYIEAGASVIQTN
TYSANYIKLAQYVLEEKVKDINKAAVRIAKEAANRDTFILGTVGGIRGQRKTEATLAEIK
RTFREQIFHLLNEGVDALLLETYFDAEELYTVVDIAKKEADVPVIAQFSLIEPGVLQNGT
PVRDAFKELENRGADVTGLNCRLGPHHMIQAFEEIPIPKRAFLSAYPNASLLDYEEGRFT
FTNNADYFKTCAEKLVEQGVRLIGGCCGTTPAHVKAIAEGVQGLLPVTEKTVRPPKIEIA
AAPAQHEPPLHEIVKKRRSVIVELDTPKTLNTARFFEGAKALQASGIDALTMADNSLASP
RISNTAIASILKEKHGIRPLVHITCRDRNLIGLQSHLMGLAALGIDQVLAITGDPTKIGD
FPGATSVYDLSSMELIAMIKQFNDGISHSGKSLHRKTNFSVAAAFNPNVRNLDKTVGRLE
RKIRYGADYFITQPVFSTEKIEQIHEATKHLDAPIYLGIMPLTSYRNAVFLHNEVPGIKL
TDEILAAMEKTNGDPAKAREESLAISRTLIDAALGYFNGIYLITPLERYELTVECTRYIH
EKTAVQGAGIV
>B1G9E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M)|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLAALKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHLSCIGSSKESLRAILNQYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCKRLVDAKVPGLHFYTLNGAAATKAICERLKG
>A0A5T1DKT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHV
>A0A420V5F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces xinghaiensis|TrEMBL
MTGPGPTPGPTRGGSGQDGAPGTTTGGTDVSTLGEILAAGERTYSFEFFPPRTETGERTL
WHAVRRVEALAPTFVSVTYGAGGSSRDRTVRMTERIAAETTLRPVAHLTAVGHSAAELRR
IIGQYASAGVRDVLALRGDPPGDPRGPWIPHPRGFRHAGELVRLVRELGDFGVGVAAFPE
RHPRSPDWESDIRHFTAKCRAGADYAITQMFFHVEDYLRLRDRLAAAGCATPVIPAIMPA
TDVRQITRFAELSGAAFPPDLARRLEAARDDPAESRRIGVEHATEMALRLLAEEAPGLHY
ITLNRSTATLEIHRNLGLPRGGPRTAPAAA
>A0A719Z6J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Typhi str. 404ty|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3M6VI93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peronospora effusa|TrEMBL
MKIIDKIHASVERQEIFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQNLSGLEMLMHMTCTNMTENDIKKALDQAKDAGIRNILALRGDPARGAAS
FEECNRGFSYGVDLVRYMRKNYGDHFCIGVAGYPEGHAESQEDKEANIQYLKEKVDAGAD
FVITQLFYDVQAFLNFVKQCRAAGITVPIIPGIMPIQNYGGFERMTSFCKTFVPEEVRKA
LAPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVP
RRELPWQTSTLSKRASESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTES
HFAPSYTWTPIERRAMWGDAPATKEDIRRTFVQYVRGEIVSLPWCDAALHAETSSVQQEL
AAANSAGFLTINSQPRVNGVLSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIDNAAK
KRSVQYHAVNLKGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLK
LWASLYEEGSQSSKLLHEIHDTYFLVSIVDNDFVKGNIWDLFKASISPSTSP
>A0A537B844|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MQADLTVEPDTAARLVGALQEDERRSIPALLAGASLELSSRDPAEIDECAALLDPGTAVY
ISMPPGQTYHGNVALAARLRRAGFRPVPHVAARRIASRDALGEYLARAAGEAGVDSALVI
AGDSDRPSGPFDSSRALLETGLFQRHGVVRIGVAGYPEGHPRIAETALETALTAKKVLAR
GAGLDLQVVTQFCFESEPILAWAAKMKGHGLPVRVGLPGPASLPRLLRFAALCGIGNSVR
ALKTRPRAITRLLVEAGPEAVVRDIARPRGAVIAGVHFFCFGGLLRTARWLRAVREGRFE
LTPDGGFRVGAA
>A0A1H2PGL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas vancouverensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSEYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLANFVRKANAGADSAITQYFFNADCYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTLSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQADASLAVWNNLKLPR
>A0A4Q8P9B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Brancaster|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7M7GUJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apis mellifera|TrEMBL
MKKTVLKRKTYNQYIDNIRNGYQSKDIEHKIVDLRNKLKNVIDTNTIFCSFEFMRVENND
FYKSFFMEMNKYHPLFYALTWKHMKNEIKNYLSSDICNIFSNNILLHLTSNNLTRNDVKI
ILKKTLDRGIRNIFVLKDSSNTNSEFPYAVDLVRFIRNQFGEIFSICVAGYPEMHPKSLS
KEMDLIYLKEKVDAGADFIITQIFFEANIFIKFVNDCKQIGINVPIIPGIFPIPNYTSFQ
KMAKICNVKIPQIILNDLQCIKDNDEEVRIYGIELLKTIIKDIIASRTTCGFHFFTLNKP
SLSSEICDKLGIFY
>A0A3D0PRU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MISDSLFRDHTVFSFEIFPPKRNASIDTVYHTLDGLQGLHPDFISVTYGAAGSGNNSATV
EIASVIHNQYGIESVAHLPCRYLSRAQAADTVKQLQENGTQNILALRGDTVSDQNPQGDF
VHASDLIAFLKQFKHLHIIAACYPETHPEAPDMDTDIRHLKEKTNAGATHLISQLFLDNS
CFYSFLKKVRAAGITVPIEAGIMPVINKKQIQHMVSLCGASLPEKFRTMMDRYGDNPDAM
RDAGIAYAVDQIVDLVSHGVDGIHLYTMNNPFVARRICKATETLFKK
>A0A078LL95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter koseri|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1C5S0Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Blautia sp|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVQLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAEI
>A0A2A9B0L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A150CWH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2V4B2C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella muralis|TrEMBL
MTLQQEVAGRGRRRAHLADLVRNISYEVMPFKNTERDVVATVPVSVPLTVTVTEAKGIDT
TLALTERLLGHGYSVAPHLPARQFANTRHVGEVVDRLREAGVRSVFVVGGDAPEPVGEFA
DAHALLQAMEAHGHPFTEVGIGGYPEGHARIPQEAIDLALKQKAPLATRVITQICFDATT
TSTWAARIAACGVGLDVHVGMPGPVNRQKLMRISAGIGLGQSARFLQKQRSLAWRFLMPG
GYNPTKLAKRLGAAVPRTDSNIRGLHIFTFNELAGTERWRRSLLASIGGEDRR
>A0A0Q0EN51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. sesami|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A4Y8QF27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sumterensis|TrEMBL
MTKATDNASRGPSRSDIRLSFEFFPPKTADAEKQLWETATQLSAYEPAFLSVTYGAGGST
KVPTLATVRHLLGMGLPAASHLTCVGATKEEVNAVVAEFQAIGVKHFVALRGDPPGGVGT
AYQPHPGGYANAAELVAGLRGLADFEVSVSAYPEKHPQSADVAADIDMLKRKVDAGATRA
LTQFFFDNDQFEHYLERVRRAGITIPVVPGLLPVHNLAQVQKFAGMCGATVPAWLAERLS
PVDDKPQERTAVAVELAVRQLEDLISRGIDEFHFYTMNRANLVSAVCDGVGLAKVDRRPA
AGAAA
>A0A2V4API8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella muralis|TrEMBL
MDRNRANHAYTALLAAPRFEILPLASVLDETSALPEGTVVTVTASPRRGLDATVETCQKL
AAQQLRAVPHLAARQVTGEEHLRELLDRLAGSGIDEVFVVGGDAAVPAGPYADGLALLRA
MAGLGRLPATVGVPAYPEGHPVLGERTLWSALHAKQAYASYVVTQLCFEARAVCRFAAAA
RDRGITLPVVAGVPGAVDTRTLLRMSVRIGVGDSLRFAKGHRSLAGRLLRPGAYLPDALV
GELAARADAGECAPAGLHFYTFNRLGATARWAAEARRRAG
>A0A081UYA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas hydrophila|TrEMBL
MGFHSARQVEALNQSLADLSGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPEMYATDLVALLKAEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDDDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQP
>A0A7V4WXM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSFKEALESGKFVVTAEIGPPKGTDIHEVIHHIELLKGKIDAANVTDNQSAVMRICSMAI
CKIALENGLEPILQMTCRDRNRIGLQSDLLGAYVLGIRNVLCMTGDYVTAGDHRDAKPVY
DVESVQLLQIVEKLNNGKDMAGNELKGSTNFFYGAVVTPESDPVEPQLLKFEKKVKAGAK
FFQTQAIYDIEAFKNFMKEARKFPVKILAGIVVLKSAGMANFMNKNVPGIRVPKELIEEL
KSAGKEKALDTGLNIAARHIKQLKDDNICDGVHIMAIGMEDKVPIIMERAGLI
>A0A397ZQV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica campestris|TrEMBL
MKVIDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGSTA
DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK
FVQVEGGFGCALDLVNHIRSKYGDYFGIAVAGYPEAHPDVIGENGLASKEAYQSDLEYLK
KKVDAGADLIVTQLFFDTDMLLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCKTK
IPAEVMAALEPIQDNEEAVKAYGIHLGTEMCKKILAHGIKSLHLYTLNMEKSALSILMNL
GMIEESKISRSLPWRRPANVFRIKEDVRPIFWANRPKSYISRTKAWENFPQGRWGDSRSA
SYGALTDHQFSRPRARDKKLQQEWVVPLKSVEDIHEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLVKVNSKGFLTINSQPSVNAERSDSSTVGWGGPGGYVYQKAYLEFFCSKDKLD
ALVEICKALPSITYIAMNKGETWVSNTSQSDVNAVTWGVFPAKEIIQPTIVDPSSFNVWK
DEAFETWSRNWANLYPEEADPSRNLLEDVKNSYYLVSLVENDYINGNIFKVFSDL
>A0A8C8FUB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
HGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTESGDHWFSLEFFPPRTASGAVN
LVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQTK
EKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKHIRCEFDDYFDICVA
GYPTGHPEADSYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVRDCRAIGITCPILPG
IFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIRNYGIEQTVGMCRVLLESGNV
PGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYI
YRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEELTSEQSVYEVF
TSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMMDELDKVNRRGVLTINSQPTINGKPSDD
PIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPRVNYHIVNVHGQNTTNAHDMQ
PNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAELYDDESPSRMIIKYIHDN
YFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPTEQPEALPGDVGRP
>A0A5F2D847|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira levettii|TrEMBL
MHISEILGKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEQTGLTIVSHLTCVGSTKEEIGEILKRYQKSGIHNIMALRGDPPKGQNEFQKT
ENGFEYAGELVGFIKANYPNMGIGVAGFPEGHPSTPNRLKEIEYLKWKVDQGADYICTQL
FFNNDSFYDFVERCEIAGIKVPIIAGIMPITSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDAYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRKIYESLGIRNFDRIV
>A0A2E1WUE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MDGAMGTELYASGVFVNVSYDGLNLETPDVVETVHRNYVNAGAEVIETNTFGANPVKLSS
YGLADRTEEINHAAVGLARRSAQGRALVVGAIGPLGIRIEPLGPTSREEAQEFYKRQVDG
LVEGRVDGFVLETFSDLNEMEQAFKAVRSRSPLPVICQVTVGDDACTSYGTSPEDVATEV
ASWGASVIGLNCSVGPAVMLEAVERMAEVTDLPLSAQPNAGLPRAVGDRKIYLASPKYMA
QYARRMIEAGARFVGGCCGTSPEHIRSIRALVGGVRPPSTRARPGSHAESHDTPIQPEVP
LGERSVWGRQIAEGTFVTSVEVTPPKGWNAEILLGQCRRIQAAEANTVNVLDHPHAHTRM
SALPAAMLIEREVEIETIVHYPCRDRNMTRMISDLLGAAAAGLHNLLLVTGRPPAMGPYP
DSTASLDIDSIGLTNVVHGLNRGVDPGGNAIGVPTRFVIGVRVSQVAVDQDREAGRLNWK
VDAGADFVITRPVFDAERLHSFLERVPELSVPIIASLRPLTSLREAEFLHNEIPGIQIPD
RVLARIANAEAHGEDAARAEGVSIAMEAFAAVRDSIAGVHIHVADGNLDGALELLSEIRD
SA
>A0A6P0EQZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter muralis|TrEMBL
MTGTVRELLDQGRPTWSFEFFPPKDDAGEGQLWTALRELERLQPSFVSVTYGAGGSTREG
TVSVTERIATDTTMLPLAHLTAVDHSVAELRHVISRLAASGVRNLLALRGDPPGADPQAE
WVAHPQGLRYAAELVELIKDIGDFSVGVAAFPEQHPRSPDLESDTDMFVAKARAGADFAI
TQMFFRVEDYLRLRDRVAARGCDVPIIAGVMPVTSAKQITRIVQLSGQAFPDELGERFAE
LDGDTAQDKRAMRAYGVEVATQMCQRLLAEGVPGIHFITMNRSTATREVYASLAGEGVDT
GAPAAVLAV
>A0A7Y2I2I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp|TrEMBL
MKAGSNLERVLEAGHFAVTAECGPPRGADPDKVLQKADLVKGNVDACNVTDNQTSVVRMS
SVAGCMLVKESGTEPLLQMVVRDRNRIALQSDLLGASALGVRNLLCLSGDHQKFGDDPQA
KNVFDIDSIQLIHLVKTMRDEGVFPSGDKLEGAPKFYIGCAINPFADPFEIRVPRFKLKI
DAGADFVQTQCIYNMDKFKRFMDEARKDGLHEKTKILAGVTPLKSAGMAKFMNRMVAGIE
IPEEFIKRIADEPKEKQAAKGIEMCIEQIQEIKEMEGIAGVHVMAIEWEEKLNEIIGGAG
LLPRPMVEQ
>A0A8D6R5Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus thermophilus|TrEMBL
MKIRDLLKARRGPLFSFEFFPPKDPEGEEALFRTLEELKAFRPAFVSITYGAMGSTRERS
VAWAQRIQSLGLNPLAHLTVAGQSRKEVAEVLHRFVESGVENLLALRGDPPKGERVFRPH
PEGFRYAAELVALIRERYGDRVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIGIPILPGIMPVTSYRQLRRFTEVCGASIPGPLLAKLERHQ
DDPKAVLEIGVEHAVRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGLRPASGQP
>A0A2R4DS37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax avenae subsp. avenae|TrEMBL
MSLSTHKAALPVSFEFFPPKTPEGADKLRAVRQQLYVRRPEFCSVTYGAGGSTQEGTFCT
VREILSEGVQAASHFSCIGATREGVREQLAQLKAMGVSRLVALRGDLPSGYGAGGEFHYA
SDLVAFIRAEAGDDFHIEVAAYPEVHPQARSPEADLQAFATKVRAGAHSAITQYFFNADA
YWRFVDDVRALGLDVPVVPGIMPIMGSTQLMRFSDACGAEIPRWIRLRLQGFGDDSASIR
AFGLDVVTALCERLRAGGVPSLHFYTMNQSAATLEICRRLGL
>A0A173SZU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum hallii|TrEMBL
MNIREYLENHKLLTDGAMGTYFDSIEKENYICSEEANITNPALVREIHRSYVKNGAQLLR
SNTFLANEGTFLSLTQAKAEAFENITLKQLIIAGYQLAKETAQEVYQEEYPIFAAADIGP
ILEERDSEEADILQQYYEICDSFLEAGADIFVLETFPDTQYVLKMAEYIRKSCPEAFIIG
QFSLTPTGYSRTGFHYKTILQEATQSGLLDGAGLNCGVGAAHMKKFLKSYIEEFGVPEDM
VLTSLPNCGYPQIVRGHAVYSDSVPYFGEKLGEISELGVQVLGGCCGTTPEYIGEIYKTV
FQAKKTEGAVKIPTKIVWGDVTKRVQKRKEAAVHITQAGEQKEAIKEKQVTNTFRQKLEM
GELVCAVELDPPFDTDDTKLLNGAKALLSTKADIITIADSPLARSRADASLMAAKIKMTT
GMDVMPHLSCRDKNRIAIRSGLLGSYASGIRNYLFVTGDPVAREDREFTKSVFDFNSIRL
MKFAQSMNQEVFKDDTIFYGGALNQNGASPENIAGRMLKKMEAGCRYFLTQPVYDKEGIE
RLTFLKERTGAKILIGIMPLVSRRNALFIKNEMPGIHVPDEVVAKYKEGASREEFEEAAI
EISKQIIEMGKGIGAGFYFMTPFNRVSLVKSILEYV
>A0A3M5WR97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. aptata|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A091A5D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas salmonicida|TrEMBL
MGFHSARQVEALNQSLADLSGDIGVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKDPA
>A0A4Q4M8H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria tenuissima|TrEMBL
MHISQKLLQAREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDDALRDAYNAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDDVDELIDHLKEKVDAGGTF
IVTQMFYDTDLFLEWVKKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTRCNIPKHWTEAL
EPVKNDDVEVREVGKHLVAEMCRKLIDAGITHLHFYTMNLAQATRMVLEELDLLPDPESP
LEKPLPWRPSLALNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPMSIRDLSELFVRYMEGKLESLPWSEQPITTEAGSIQDDLIN
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEHISEIITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDVVDTWYLLNIVHNDFHATRGIFPIFDGLEVKDMDKPLVNPSVDL
PSANGDEATKVVNGGSHTNGTNGEQAEPHKEENPSLIDAAKAAAVEVTNGMRSLAMSN
>A0A024UV34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces invadans|TrEMBL
MGKIIDRLMELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPRDQLREILKNVRAAGIRNILALRGDPPIGSE
RWKPVPGGFHNAVELIRFIREEHGDWFCIAAAGYSEVHSEAWNNPNLPPSDQARQLDMIR
LKEKQDAGADFIITQFFFDVDKLLQWIRDCRQLGISIPILPGYLPIQTHNSFLKFTNWCK
TSVPPQVQEALVSIKNDDAAVKKYGIQLAVDTCKKLIANKLSLHFYTMNLARTVRAVLEG
LHLIERERGLPWGAPIMRNKDGSLEKSIEQVRPIFWSNRASSYIARTSEWDDFPNGRWGD
RTSPAYGELSEYYLAYKRPKVARDQLWGRPQTEEDVWNVFVKFIEGSVKQLPWCEQGLSG
ESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPRLM
QRLVVALADYPNLSYHAFSANGTEYTNSPGPSVTAVTWGVFPGKEIIQPTVVDTASFAAW
KDEAFELWLSQWASAYEPETVSHQLIKVPSIAFASFSAFLETMMPFDGVAHIRQLRPRER
RGQRLHEWYDASRRQSC
>A0A0G9MB54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium adolescentis|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVDEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREKRPNLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCESRVPEKLAVLLDKWGSDTALLKEAGIAY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A432TA24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp|TrEMBL
MFEKFCDVLCLEKEFITVEINPPHGASIDSIIAEIKKYNLQDKVTGFSCTDNPLAKLKMS
GVLSAIKVQQAFKKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKFSDQPE
VKGVLERDSTLLLSIIYHLNNGVDYSNKALHPKPKPIYPFAVTNAYAKDMNSLKKRMVKK
LNYGARAIITQPVYDIDNAKELLALFEEAKTLSIRDTAKEAHLVLGQFPIVRAKTANFID
DKVPGINVPKAIIDEMNLAAMDGETKEQEVGFALSKKIFDEIMQTHGKVHLMTHNRFDLC
AQLIG
>A0A7R9PZH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Medioppia subpectinata|TrEMBL
WGVLAVLKDRVSAVKWDAAPESGEVVANGQGVKDGVVSNGVPARKTSQPTAPYVPLIARM
RKRMADGNVPFFSFEFFPPKTQEAAINLVARFDRLRQTGPLFCDITWHSAGNPGADTETS
SITIAGVALNYSGLDTMLHITCVGMTEPDLRRHLERAKTIGIRNILALRGDRVGDHYDDD
SQHELAPEFRYAVDLVRYIRREYGDYFTIAVAGYPSAHPESESVAEDLQRLKEKVDAGAD
FIITQLFFKSDVFVKYVKNCRRIGIEVPILAGIMPIQSYESLEKIGKLSKLDIPDTLLND
LDIIRSNDEAVRNYGIQWAVGLCRQVLAANVTPGLHFYTMNREVATCAILKELGLMSQVS
RPLPWWPTGNHKRAAEDVRPIYWSGRPRSYVCRTQSWDEFPNGRWGQVDSPAFQTLENYY
LFLEPKHSRKELLQMWGRELATEEDVWEVFHCYVSNAKNKYDKTVSVIPWNMDPLSAETS
LLVKQLSQYNKRGVLTICSQPNINGVDSTHPVHGWGAKGGYVYQKAYLEFFTNEKNVMAL
IEALKNYPMVNYQIVDSTGKKSYSNFEDNKAIAVTWGVFPGREIIQPTVVDPISFKVWKD
EAFSLWRDKWGHLYEEDSLSRRVLDDIHDNYYLVNLVDNEFPKECCLWQLLEDMFTIRSD
SH
>A0A1Z1FGU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceicoccus marinus|TrEMBL
MSKPQIHPNWDRPARVMTDGFSIEITAKDVDSLREAAPGIPEDHPVAITFLPGEDFAARI
AATRAVRELGFEPMPHFSARRIASAQEFEDYLQAVVDQADVKRCFVIAGDPTEAEGPFDD
SSALIGSGAFERAGITAIGIGGHPEGHPYMTEQQCWQVLHDKCAMIEARGMAPLIVTQFA
FDADRVLDWVLELRRRGIHDPVRLGVPGPAGIKTLMRFAARCGVGASATVLSKYGISIGK
LIGTAGPDRLVDAIAKGLTPEHGPVRLHFYPFGGVPKTVAWINEYARTH
>A0A351J2F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MRISSMFKKDRPLYSFELFPPKPNSPIKTIYETLEAIADLNPAYISVTYGAGGNPADNST
FDIACLLQEKYHITPLPHITCITSSKDEINNRLAKYQDAGIENIFALRGDENPHIAAKDD
FRYASELITYIKGRFNFDITGACYPEGHIASPSLEQDIQYLKRKVDAGASHLISQLFFSN
EHFFDFVERCRAVGIHLPIEAGIMPVVNVKQIQKMVTLCGASLPRKLTRMMQKYEDNPAA
LRDAGIAYATDQIVELLAAGVDGIHLYTMNNPYVARRITENIAGIIK
>A0A5S9PNU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zhongshania aliphaticivorans|TrEMBL
MANRYSFEFFPPKTEAGREKLKDTRSQLASLNPEFFSVTYGAGGSTRDNTRDIVLETKKA
GLSVAPHLSFGGDEEADILALLNSYKDAGIDRIVALRGDIPSGMGATRLIYARGLVEFIR
KHTGDHFQLEVAAYPEIHPDAKTYDADIGFLKDKLDAGADSAITQYFFSADSYFYFMDAC
EKAGISKPIYPGIMPITNFTNLARFSRNCGADIPRWLAQKLEGYGDDQQSIIEFGKEFVT
ELSHILMEGGAPGIHFYSMNQVEPIKSIAQAVIESHP
>A0A8C1UMP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVQDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCECDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGAHFIVTQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNCRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQEEGSPS
>A0A353N4E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MGRISIELVPRSRESLQSDLELVRTGFPQIDTVNIPDLLRFQLRSWDGCRYVKKYYEKVI
PHLRAIDLDLKEPLPFAEHLQELGIEEVLVLTGDPPQDMSRKIYPSDSIDLIRKFKREHP
QIKVYAAIDQYRTSMRMEYDNIKRKLDAGADGFFTQPFFDLRLMQIYAEMLQGLEVFWGV
SPVTSEKSVNYWETKNHLIFPAGFEPTLEWNLRFAKQALKFTEELNAHIYFMPIRTKLQV
FLGGLFD
>A0A8H9YRK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas tritici|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKSDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITNMCEDLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0W7YZY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas kerstersii|TrEMBL
MPTACREGRPGVSNVATAFPISFEFFPTKTPEGAAKHVQVRKDLYARQPEFCSVTYGAGG
STQAGTFSMVRDIQAEGMQAACHFSCIGATSEKVRSELQQLKDMGVKRIMALRGDLPSGY
GLGGEFHYASDLVAFIRKEFGDWFHIEVAAYPETHPQAKSPDADLRAFATKIQAGANSAI
TQYFYNADAYLRFVEGIQALGVSVPVVPGIMPITNSSQLMRFSDATGAEIPRWIRLRLQA
YGDDVASIRAFGLDVVARLCEQLRANGAPGLHFYTMNQSAFTLELCDRLGL
>A0A534FSA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPIRPGHTSPGRFERVLRAGQFAVTTELDPPDSADPEEVYRRARVFDG
YVDAINATDGSGANCHMSSLAVCALLTRVGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQALPVFDLDALTLLETARTLRDEHHFLSGRKITHAPRVLLGAAE
NPFAEPIEWRAERLAKKVAAGAQFIQTQFCFDVPLLRTFMNRVEDLGLLDKVFVLVGVGP
LRSAKSAEWIRTHVPGVHIPDEVVKRLAGASDGALEGRRLCIDVIQEIRTIKGVHGVHVM
AYRQEEAVAEIIQRSGVLGGRVPWNPGRDPPANTNRMASEPTPSAALEPARS
>A0A4J1VZ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPYFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A132MW84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carbonactinospora thermoautotrophica|TrEMBL
MALGVPSVRPDRAATIRELLAGGSRSYSFEFFPPKTDVGERQLWQAIRRLEPLRPTFVSV
TYGAGGSTRDRTVRITERIASETTLTPVGHLTAVNHSVAELRHVIGSYAAAGVRNVLALR
GDPPGDPQGEWRPHPEGLRYAEELVRLIRESGDFCVGVAAFPEKHPRSPDWETDIKYFVR
KCRAGADFAITQLFFYAEDYLRLRDRVAAAGCDVPILPGIMPITNVRQIERIAVLSGAQF
PPELAERLHAVEDDPAAVRAIGVEFASALCERLLAEGAPGLHFYTLNRSTATLEIYEALG
LRDRGNAAERRPA
>A0A818EFZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MLDNGINIKTISNSSNDIVDLKRSESENGIGTTKGSSPQPAKYVSLAEKIQERISNHERW
FSLEFFPPTTSNAAANLIGCVERMALAQPLFCDITWRSTGDPAGNKETSSMMIANTMLNY
CNIDTMLHITCCGTKKPQMIQYLNRAKEVGIRNLLALRGDPPVGEQWDPDQTDFRYATDL
VKFIRETFGDYFVICVAGYPQGHPDTESYEEDLGYLKQKVDAGADFIITQLFFQAETFLK
FEADCRAIGITCPIIPGIFPIQGHASFRSVIRLAKLDVPKEMLDSIESMRDNDEAIRDYG
VQACIDLCQKLLDSGKVLGIHFYTLNREYATTEILKTLGIWLEETPLRALPWKKTSQSHA
RSQENVRPIFWSLRPKSYIHRTTDWNEFPNGRWGFSFAPSFGALTDYHLFYMKMDASHDA
LLDEWGHSLTSEEDVWKMFACYISGEKNVLGKSVRHFPWKDEEVSLETNLIQSQLVEYNR
KGILTINSQPPVNGKPSSDPIVGWGVPNGYVYQKAYLEFFTSASNIPALRAVLKDFPNIN
YHFVNKSGEVNETNADGEQATALTWGVFPGKEIVQPTVVDPVSFMIWKDEAFSLWMERWG
KLYEPGSPSYSIIEEVSNTYFLVNLVDNDYPQGSCLWKVLDAMLEYQKSTNQDVKS
>A0A5I8NA95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella paratyphi A|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5P0YV15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces alkaliterrae|TrEMBL
MALGIASTRTDRALTIRELLASGEQSYSFEFMAPRSEKGERTLWNAIRRIEAVRPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVDHSRAELRNIVGQYADAGIRNMLALR
GDPPGDPMGEWVPHPEGVAYAVELVEMIKEAGDFCVGVAAYPEMHPRSTDWESDIRHFVD
KCRAGADYAITQMFFYPEDYLRLRDRVAAAGCQTPIIPEIMPVTNVRQIERFARLSNATF
PPELAERILAVKDDPAAVRSIGIEYATELASRLMDEDIPGLHFITLNHSTATLEIYENLG
LHERP
>A0A496XCZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSRKKPRISFEYFPPKTEQGKDKLLNVTTPTLNELNPEFFSVTYGAGGSTRDTTLGVVSA
IRETGIDVAPHLSFGGDDENTINALLETYRERGIKRLVALRGDMPSGMGTAMQMVYANEL
VAFVRERTGDHFNIEVAAYPEIHPEAESYDSDIRFLKGKFDAGANSAITQYFFNVEAYFY
FLDQCAANGIDQPIYAGIMPIVNFDNLLRFSRNCGAEIPRWICQRMAVYAGDQDSMRKFG
IEVVTQLCQTLLDSGAPGIHFYTMNQVEPTREICNNLNL
>A0A443UPJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A2E5DFM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKFKDSIYDTFSFSADLNLGAVGSVEDLLGQARILSGSVDGIHVSDGPNDGVHFPALAAA
RLLIENDIDPILQISCRDKTRSTLEIEIAGALALGVTSMLLVRGESAGISGTSDRIVKVS
TTELIQLVRSLEDRAEQANLSVGTIATVFKPAADWRPQALLKKTHAGANFIRTQLCFDTD
KLNVYMPNLVRSKVTWKAPIFVNLAVLPSAKAAKWLAENLRGSLIPQKVIKRMEQAVDPI
SEGVDVAAELIAEFNTIPGISGVCLMTPGPPELILEAIKASGVRQE
>A0A0F1LNS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella aerogenes|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A4P6JHF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDTFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVVNRNQILRLLKNCNTPLPAKFIRILEKYEHNPLALRDAG
IAYAIDQIVDLITEDVAGIHLYTMNNANTAHSIHASISSLFTV
>A0A538E2D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPLAGAEEEVLEHVPLEVKVTVTTSPRKGLEPTLELAERLAAHGYTVVPHLAARHVRDRV
HLAKIVDRVRAFGATDVLVMAGDAPEPAGEFEGALPLLRALAELGSPFAEVGITGYPDSH
AFISDSATIKAMFEKEEFGTYIVSQICFDPQVTAEWVAAVCERGTRLPIHIGLPGAVSRS
KLLRVSQRIGVGESIRLLQNDGAGGDDDFDPGPLVEGLEASVHERRNVAGFHIFTFNELE
RTEYWRQRMLAPVRSK
>A0A6I3D0E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTYISDLLAAGRTCSFEFFPPKTDDAARALEQTIAELEPLDPSFVSVTYGAGGSTRERTR
DVVINIERNIGITAMAHLTCVGHTRAQLDSLLDEYKAAGVSNILALAGDPIVDDNGVVAE
SEFEFAMELVELIKEKSGFSIGVAAHPEGHPRSEDLYSDRRHLADKLNVADFAITQFFFE
ADPYLRLVDGLSAFGCDKPVLPGIMPVTNAAQVVRFAELAGAAFPPHLAARFDAIADDPD
AVRALGVELASELCQRLLDEGAPGLHFYTLNRSTATREIAANLGLGDASSTGA
>A0A6L6E8J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSQDLRTTTFSLEFFPPKDVAGEERLWQALGQLQPLKPDFVSVTYGAGGSTRDRTIRVTT
EITARTSIPTVAHLTCVGSTRSELIEILKQYKSAGIKSILALRGDPQSGPRGVWQENIDG
FNHADQLVELAIQTGDFKVGVAAFPDGHPASNFNFEKDVDVLIRKEELGATFATTQFFFE
VSKWQKLVDRLAKRGSTLPIIAGVLPITNLKQLNRMSELSGTQVPDEILKHFEGKEDNPE
EVKKIGIDIATSLGEKLLELKAPGIHFYTMNSSESTVAIAKNLGLIKP
>A0A6I3BKM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MERRKRRAGKSVSQRVNNFPSRLAERFSTSERVFTVEFPAIDGGNLSAVKSRVDHLLPWF
DAANATDSPAAHAHASNVAIAIALQQCGLEPILQVVCRDKNRIAIQSDIMGAALHGVRNI
ELLTGDDVTAGDEPEARRVFDIDSAQAIKIAATLREGRYLSGRKFPDAPDLFIGAVENAA
APPLEYRAERVSKKVSAGASFFQLQICFHGDRLEKFVSAVNATHPSLPLLPTIVLVKGAK
ALKFMNGNVAGIDIPAEIIAQVEQASDPKEAAYQLARAQAEHALSLPGVRGIHFTDFCHD
DSLVRLMRDLGVTPRSIGKS
>A0A1D7ZDS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia stabilis|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTDLCRRLIDAGVPGLHFYTLNAAAATRTICERLDV
>A0A5A8CTP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cafeteria roenbergensis|TrEMBL
MAARIDELMAAHSGDAPWVAFEYYPPRTEDGVNNLKKKMPRFKAQKPLYIDMTFGAGGST
SDLTLDLCKEAKAAGLEPNMHLTCTNMPQEKIYEALEGAKAAGIRNIVALRGDPPLGQER
WEAVEGGFTCALDLTKHIVKTYGKDQFCISTAGYPEGHPGAIKKVAEGQELSDKEKRRVV
SLEDGDYVCSDADFAKEMEYLKAKVDAGASLIITQMFFDVDVFADFLEACKEYGITVPVI
PGLMLVQNAGGFGRMTAFCKTRVPASIREGLEAVKEDDAAVKQFGIDLGAKMCEQLMALG
CKGLHFYTLNLEKVTFGVMRKLGLFDEDAAAAAAAAAEPAAAASAGAASA
>A0A0P9VMB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. helianthi|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRSLLTHYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFT
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A8H3NEZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus udagawae|TrEMBL
MHVHDMLAENDAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEA
WEATEGGLRYAKDLVKYIREKYGNHFNIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
VITQMFYDTDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEAL
EPVKNDDAAVKEIGKRLIADMCRRLLAAGIKHLHFYTMNLAQATQAVLDELKLIPSEETP
LQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSIRDVTQIFVRYLEGKLDRLPWSDSPISSEANVIKDNLVQ
LNSRGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNP
DLTYHAVGKKGELRTNTRDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQDMMDNWYLVNIVNNDFHNTYDLFDLFNGLEVKDFDVEVVPDTVETK
SQPNGAAPEEVAVKN
>A0A6B2QJW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGK
ARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKHHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKKAKSFLIKNNYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVTSGKEFSPEITHFSC
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAKLLLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKQT
EILKDKLIPTVPLETRGTSSWKNWYLATEA
>A0A3T4P5G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A831N995|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELAGEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A4U8I182|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Corvallis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A132HDK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus metallidurans|TrEMBL
MTDRYFSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSTRDSIRQILQTYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQARSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRAMGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDKEAIRAFGLDV
VTDLCTRLLEAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A4U7YYP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Kentucky|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6N1L038|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAADLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVEKVQAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNSSNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A512TQE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium butyricum|TrEMBL
MIKEFLNNNILICDGAMGTYYSEKTGNDISYCEFGNLNDKNTIRRIHEEYIEAGAKLIRT
NTFSANSKELGVSRKTLKDIIESGIEIAKEAVYNKEVFIGASIGPIRENGADENVVEVLE
EYKFIVDCFLDNNINVFIFETLSNLDYLEEVSTYIKNKKPESFILTQFAVKPDGFTRDGY
SVSKIVGEVKKINTIDSYGFNCGSGPTHALELIKKIDIGDDIVSSLPNAGFPEIIHERTV
YPNNPVYFARKVKEIKKLGVSIIGGCCGTNPSYISKLRDTIDNKPEPGDKIKRYEHETYN
EKNIIKNTFKEKVKNGDFVIAVELSAPVDTDINKIMTGAKVCKDNNIDIVTVPDSPMSKV
RADSVVMSSKIKREIGIEAMPHMCCRDKNTNAIRSSLIGGHIEEIRNILAITGDPISDAS
RIETKSVFNLNSFKLIELINDMNNEVFTSDDIFIGGALNLNVINKEVEYGRMMKKVERGA
KFFLTQPIYDDSAVEFLKSIKERTDVKILGGILPVVSYRNAMFLNNELPGVTIPQEILNR
FSEDMSREEGQNIGIDIAVSMGKKLKGICDGLYFITPFGRVNMIVDIVNRIKEV
>A0A4U6BKF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afipia massiliensis|TrEMBL
MTSETSAPTGSQGQKRPAISFEFFPPKTEEMEHNLWEVINRLAPLTPNFVSVTYGAGGST
RERTHSTIARILSETKLTPAAHLTCVAATKADIDDVVARYHEVGVRHIVALRGDPTTGIG
TAYAAHPDGYQTSADLVASIKKRYPDIDVTVSAYPEKHPESADFDADIDALKAKVDAGAS
RAITQVFFDNDLYFRYLDRVRARGIDIPVVPGIMPMHNFKQARNFVTRAGTTVPSWLADK
FEGLDDDAETRKLVAATVAAGQVQKLAKHGVENFHFYTMNRADLVFAISHLLGIRPNGAQ
KAA
>A0A8H8JAU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceratobasidium sp. AG-Ba|TrEMBL
MVFLQRRTPNGMKLVDKLAQHSSGVPYFSLEFFPPRTDQGFSNLLTRINGLSGLRPIAVS
VTWGAGGSTRDRSLELAGFCQADNGLDTILHLTCTNMERGTVDDTLTTAMERGVKTILAL
RGDPPRGEEYWIPTDPRFQHAEDLVTYIKEHPVFSTHFCVGVAGYPDGHSDGGTEDEQLT
YLKRKIDAGAEFIVTQLFYDVERFKVWLGKVRARGITVPVIPGVMPLQTYAMFTRMTTLC
NATVPERLQADLDAIKHDDQLVKDYGVTLAVSMIQSILADGDVKGVHFCTLNLEKSVRKI
LDELGWTHVPTHTTNQIIIDSTESPHVLPPPADSSHPITFTISPAEATQHATSSLNETRI
GASRAAAEVLDRGWDDFPNGRFGDAKSPAFGNTDPWDGGGLGVPPHAAVAQWGHPSTMDD
LTSLFLSYLQQNTPTTPFSPSPLSAESVSILPELISLTSRGLWTVASQPAIDAALSSDPV
VGWGPRDGRVFQKAFVEFFCEEETLRKLIKTVEETGDGWITYFAGNHEDGFETNVPDGGS
NAVTWGVFPGQEIAQPTIIERDSFLAWKDDAFTIWNDFGLCYPPNSPSRKLVEEVTKTRW
LISIVHHDYKSPNSLWEFLMM
>A0A496YJN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSKFRERLESGEFLVTVEASPPKGTETADFLAMLGKLAGRVDAINLPDSRAANIHLGPLA
ASILAKEKGLEPILTISCRDRNRIAISADLLGAYVLGIDTILCVSGDYVSFGDAPQAKPV
YDLDSVQAIKMIRGMEAGEDIGGNVLKGTPRFCVGCVANPVADPFEPHLLKLEKKLAVGV
DFIQTLDIYDLNAAAPFLDYVRDKGIKALAGLRLVTKRDVDLWENRRLPGNDIPREIISE
VKEAPTEEEALQKSRARLVTMLKEIRASNMWAGAHITMEGHEDLIPQILTEAGLGR
>A0A7D9HXG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paramuricea clavata|TrEMBL
MVVFTVSRFMLKRVDSCSRSMWRDKVPGVRDPPHGEDFEVVDEGLVYGTDLVKHIRQEFG
DSFTICVAGYPQGHPDCSSYEEDLIHLKEKVDAGADFVITQLFFETKTFLKFVDDCREIG
IDVPIIPGVMPIQSYDSLRHLVKLSKLSIPQDLLDAIQPIKDDDKAIRNYGVDYTVKMVN
ELFSNGVPGIHFYTLNREVATTEILKQTSLWSLEPLYARSLPWKPSANVKRIKEEVRPIF
WASRAKSYVHRTSEWDEFPNSRWGDSAAASFGDLSDYHLFYLRNRTKKETLLKMWGEQLT
SVQDVYDVFVCYISGEKNVNGTKVTMLPWNEDELAPETSEVSEDLVELNRKGVLTINSQP
HANAAKSTDPVFGWGGAGGYVYQKAYLEFFTRKEVVDKLLEVLGTNYPSVSYHVVDHTGE
VDTISEDLASPVAVTWGVFPGKEIIQPTVVDPVSFQIWKCRCCAASFKWLDRNIIADFRE
ESSFQISHLVVARVYKATFFTLHRVTEAFFLQCPPLRWNKWAT
>A0A5B0Q3F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia graminis f. sp. tritici|TrEMBL
MVKKVVQLIESLKDDQVYFTFEYFPPKTIDGLSNLYARIQRMANLKPSCAHVTWGASGST
SDTSLEIAAMVQDQLAIPACLHLTCTNIQRTHLDQTLAQAKESGIVNILALRGDPPRGTE
HWIPTDHEFQHAIDLVKYIRKEHQDHFCIGVAAYPEGTTEFDQDQELNYLKQKVDAGADF
IVTQLFYDVDIFLNWVKACRNLGINVPIIPGIMPIQSYDGFRRLTALCKTNIPESIHSKL
IPIKGDDQAVRDYGVELSTQMIKRLQVNGFKSFHLCTLNLERSITRLVNQLGWSPGGIKH
CQPLLGPSVKIGTAEIVQGGLSVGWDEFPNGRFGDQRSPAFGLREGYSSSLTSAFSHLTT
DVHALWGTPTSLKDITQIFCAFTQGKLPSTPWSEEPLALETSSITPFLLKLNQNGWWTVG
SQPAIDGADSLDSVVGFGPQGGRVYQKSFVEFFVPHAHLEGLLSAVDDYNKEHSDGVAQL
RYYAGNCNQDQIRSNMAPGETNAVTWGVFRGAEVVTTTLIEAQSFKTWKKQAFEIWNDWA
ESFEPNSANQRLLNQIEDSYWLCSLIDHDFKQPEHLWSFLIAHQQRLLSHQSL
>A0A0N4UK25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dracunculus medinensis|TrEMBL
MNGLSSSSVLDATSECTTDGLNSSNGHKKTAHAKISPLLDSELFERSLYIPLHNRINQRI
QDGSPFFSLEFFPPKTVNGVSNFFSRVERMREGNPLFVDVTWHTGSDPGNLKKETSSTSI
AAGCLNYCAVDTMLHMSCINYSKKQTLRHLEQSKIAGLRNILALRGDLQKQIGIRVRCAS
GESLLRFAEQYELFVTNTYLRYQSMWNCADNQHSNKIDYILISRHWKRCILDTRSYRDAN
NFHGSDVMVRHKIRIKLIICKFNHDALSVVPNITDSPVEPYVRNCGPPTQEEEMISVIHK
LKTYKTRRRWSLGRILQILPGLGCSCDDQISILKKIHIETSLQVSACHRQYCQLFYRLLP
SIQLAGQFFEAQ
>A0A6B4JJ48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MNIKNLFKDKKVVFSFEIFPPKTTSSIQTIYDTLDDLKGLNLDYMSVTYGAGGSVKNNNT
IELSSLIKNKYGIEPVSHLTCINLTKKDVEYYLREFEKNNIENILALRGDVPIGSKITGE
LNHANELIKYISDNGKFNIAAACYPEGHIEHKGLYREIESMKRKEEAGVSYFISQLFFDN
NLYYNFQDEVRAANINLPIEAGIMPVTNKKQIERILSLSGASLPDKFKRIMERYEHNPEA
LRDAGIAYAVEQIVDLISTGVDGIHLYIMNNPYVAKRISQSIESILLTVNQI
>A0A0C4US05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria nemorosa|TrEMBL
AYGIHLGTEMCKKILAHGIKTVHLYTLNLEKSALAILANLGLIDMTKIKRPLPWRPPANV
>A0A374NG72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus bromii|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A2E2L8M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MHRAAPLDACPKNMTYGPCGGVNPDGSCEAHPDPCVFLQRDLPVRWPDAATTPVPAPTAA
ATEVADILARRALVMTGFPARPMVADDVSRVAEVLAPHTDAALSGDAATSRTQFPPSYRG
HLMTAAGMRAWIGVNARDRNRVALEGELAALRDAGVAGVHCVTGDHTETGDRPDAAPVFD
LEATTLLPRARAHGLLPSFAESPAAPPQAMRGPRVAEKQRAGGRLCLTQYCGGVDEVAAF
IERCRGAGATAPVLPGVPVIVDDDGAALLGSFHAALLPPGYAERLRTARDMRSEGIRLAI
EYGSALLEVPGVAGVVVAGGARRGDEIAYAHALATIARELGGGA
>A0A139PJH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A252A375|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter orientalis|TrEMBL
MSLSRLSVELIPRSADALRDDIAAVKQLLPAADTLNIPDLMRFPLRSWDAAAQMQPLFPR
IVPHVRAIDIAPDAPLPGANQPGLEEVLVVHGDPPADLAHRTYRNSTESIIRRYKKEAPH
LRIYAAFDPYRRAPWHELEEIARKKEAGAEGFFTQPVFDLKLFDLCREWLSGETVFWGLS
PVIGPRSRSYWETTNRVVFPKNFVPTLEANITFAQTVLKSLATDKGHVYLMPLRVKLEQY
LPALQAVLS
>A0A7X3ZS93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MSGRLRDWIAGDGVHLIDGAMGTVLYESGVFVNQCYDELNLSEPDLVLGVHADYVRAGAE
LIETNTFGANPVKLEPFGLEPSVYEINVTAARLARQAAGGRAEVLGAIGPLGIRIEPWGP
TSVDEAADLFGRQVAGLAEGGVDGFMLETFSDLDELLQAVRAVRRVAGDAPVFAQMTFGD
AGHTEYGATIEAAAAALDGAGADVIGLNCSVGPSSMLLGVERMVAATSRPVSASPNAGLP
RDIGDRKIYLASPEYMARYARRMVETGARFVGGCCGTSPEHTRLTATLLGTDGPGPARVS
VSSPSDAGGREAAEPPPLADRSALGRRLARGEFVGAAELTPPHGWDPGELVAGAARLRDA
GVHTVHIVDGPAHRSRIASLPAAIVVERELGMETVPHYSCRDRNMLGMLSDLLGAAAAGL
RNVFLITGDPPRGGPYDTGGVYDIDSIGLTNIVQQLNLGLDPGGSSIGVPTSFVKGVAVN
PGAVDPEEEIRRFAWKAEAGADFAVTQPIFNPENFLAFVREIEGFGVPLLVGLWPPLSLE
NAEFLAHEVPGVDVPSEVLERMARAQEGGAEAAAQEGVDVAREVLDAIRPHVAGALVSTP
GNEVDRAAAVLAEL
>A0A078M824|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas saudimassiliensis|TrEMBL
MTTNKSIPVSFEFFPTKTEAGHEKLIAAAHVLADQQPEFFSVTYGAGGSTRDRTINTVLQ
LDQQVKIPTAPHLSCVGDSKEDLRALLQQYRAAGIRRIVALRGDLPSGMGRASGELRYAN
ELVEFIREETGDHFIIEVAAYPEAHPQARNFEADLENFVRKAKAGANSAITQYFFNADCY
FHFVDRVRRAGVDLPIVPGIMPITNYTSLSRFSDACGAEIPRWIRKQLESYGDDSASIAA
FGTEVISQMCERLVAGGAPSLHFYTLNQAEPSLAILRNLP
>I1JZE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycine max|TrEMBL
MKIIEKIRAASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVQHIRAKYGDYFGITIAGYPEAHPDVIESDGLATPEGYRNDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKVSRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALSDYQFMRPRARDKKLVEEWAVPLKSVEDIYERFRLYCLGKLRSNPWSELDGLQP
ETKIINEQLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKL
DALVDKCKDRTSLTYMAVNKDGSWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFNVW
KDEAFEIWSRGWASLYPEDEASRKLVEEVGGSHFLVSLVDNDYINGDLFAVFADF
>U6CVU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neovison vison|TrEMBL
MVNKPRGDGGPPPRSEGSSSGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSQGQITDYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYATDLVRH
IRSEFGDYFDICVAGYPKGHPDAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDDAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFAHYLSGEPNQHGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPEPEQDAQAL
>A0A671FQ00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhinolophus ferrumequinum|TrEMBL
MLQAGPGGAIPLESDPVTLNVCWPHLYQPLQSLAGVPSFHLPSAAAAAPQPSLWSGGFVP
AHLSLCGSPSSSLKLLLCHNSAHSRHTRWGSFLCFSSAGSVSEPAEMDHPKPKVLPAGHH
CPSLGMWALEAGSVRFSVPPSISRNSVMVNEPGGHGGPNPCLEGSSIGRESSKVRSRCST
RGLKPERHERLREKMRRRMESGDKWFSLEFFPPRLAEGAADLISGFDQMRAGGPLFIDVT
WHPAGDPGSDKETSSMTIAGIAVNYCGLETVLHMTCCCQSQEKITCHLHKAKRLGLKNIL
ALRGDPVGDQWKEEEGGFCYALDLVKHIRSEFGDYFDIGVAGYPKGHPDAGSFESDLKFL
KEKVSAGADFIITQLFFEADTFCHFVKACSEIGITCPILPGIFLIQNYHSLQQLVKLSKL
EVPQQIKDKIEPIKDNDAAICNYGIDQAVSLCQTLLASGLVPGLHFYTLNRTMAAIQVLK
RLGMWTEDPRRFLPWAVSAHPKRWEEDVRPIFWASRPKSYIYRTREWDEFPKGRWGNSSS
PAFGELKDYYLFYLKSTSPKEEELLKMWGEELNSEESVFEVFMHYLSGEPNRNGCKVTCL
PWNDKPLATDPSLMKEKLLWMNRRGVLTINSQPNINGQPSSHPVLGWGPSGGYVFQKAYL
EFFTSPKTVKALLQVLKKYEFRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPT
VVDPVSFMFWKDEAFALWIKQWGKLYAEASPSQEIIRYIHDNYFLVNLVDNDFPLDNCLW
QVIEDTFELLDRPPQTDRDMEAT
>A0A1H8K3D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium luteum|TrEMBL
MTATGISACNDRPAFSFEVYPPKSVAAASALTRTIDHLAAAGPEFISVTYGANGSSRTSS
LDVLRYIKDHTTADAMAHLTCVGSSHAEASRLIREFLDAGIRSFLAIRGDAPQGAAEGDT
TFLGDLHSAGELVQLIHRVQAERVPYIETVIPGLPAARGLKTERSRVRIGVAAFPNGHPN
SRSVAQDIDTLLAKQAAGANLAITQLFFHADDYLSFIQKARSAGVLFPILPGIMPVTSPN
RLRRILQLSGEKLPAALSIALEVEPTEEGQRQIGIDYAVRLGQDVLAGGAPGLHLYAFNQ
HETVLSVLEGCGALPVPATMP
>A0A2S5T5G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schlegelella thermodepolymerans|TrEMBL
MTTTPTTRLPVSLEFFPPKTPEGVDKLAAVRQQLYALAPQYCSVTYGAGGSTQDGTLQTV
QAILAEGVDAAPHFSCIGADQASIREKLQQFKTAGVRRIVALRGDLPSGYGGFGEFRYAS
DLVAFIRAETGDHFHIEVAAYPEMHPQARSPEADLQAFATKVRAGADAAITQYFFNGDAY
FRFVDDVRRLGVEIPVIPGIMPITNSSQLMRFSDACGAEIPRWIRNRLQSFGDDKASIQA
FGLDVVTALCERLRAGGAPGFHFYTMNQAGATLEICRRLQLL
>A0A6J6H9V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTEGFSIAKALTAAAPTLSFEFFPPKDEAGANSLRNSIEELMTLSPDFVSVTYGAMGSNQ
DSSVAIVEQLSKIVATVAHLTCIGASTSGIQNLLMRYQSAGVAAILALRGDKPKGYDEQP
AGDFTYASDLVRQVKQFTSFEVGVAAFPEKHPESHSLADDIRILKMKQDTGASFAMTQLF
FDVEAYSQLVSSARAEGVTIPIIPGVMPFENARQVLRMAQMSGATVPPELDLKLSQAFSE
EAARTIGMDFSVHLVQDLLAAGAPGIHIFTLNQHRATLELANSANLA
>A0A353FG05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
MKVIEHIKQAKETIFSFEILPPLKGQNIRDIYNTIDPLMEFKPPFVNVTYHREEVVYKRL
NNGLLEQKVVRKRPGTVGICAALQNRYKIDAVPHILCGGFSREDTENALIDLDFLGIENV
LALRGDSIKGETYFVAEKNGHTFACDLVGQISDMNKGIYLDEELKNNTPTNFCIGVAGYP
EKHFEAPSINNDVQNTLKKVQQGAEYIVTQLFFDNTRFFEYVEKCRQVGISVPIIPGIKP
IATKRHLSLLPHRFHVDIPDELVKSVVNCRDNEQVREVGVEWAIQQCKELKEAGVPVLHF
YSMGKVDNIQTIAKAVF
>A0A6J5Z7J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSTLEHKLTSTNEMVFTAEFHSLDGNGLEKAKKYADRMLGWFDGVNSTDNTAAHAHASNV
ATAIAIKQLGLEPIMQVVCRDKNRLAQQADIMGASMFGVENFVALTGDDVTAGDEPEARR
VFDLDGPQLVRLMNTIKRGEYMSGRKIDPAPHMFIGAVENPGAPPFEYRVERVAKKYEAG
AKFLQLQICYHQDRLERFCAGVKDAGLAGKIAIIPSVVLVKGPRPLNFMHNSVPGIDVPA
DQIARVESASDPAEAAYLQTLEFAQHALAQPGVRGLHITDFRNDETLERLMTDLGRVRQT
STNEVKDDHAYSA
>A0A6J6AZF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARISDLIAAGRTYSFEFFPPQTQAAQMSLGRAIAELSPLAPSFVSVTYGAGGSTRERTR
EVVTWVRKETDITPMAHLTCQGHRRSEIKEILDNYADAGVENILALGGDVPLDGEVQPSD
YTFASDLLDDVLADGRFSVGVAAHPELHPRSPDRATDRRYLAAKLGSSDFAITQFFFEVD
VYVRMVDELRALGVDKPVLPGIMPVTNKSQILRMAAMSGAAFPEWLAQRLEAFEDPEDIR
RVGVEAATELGQALLDAGAPGLHFYTLNRSTATREIYANLGLPIEQ
>A0A8E7NFI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A442HNR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFAEMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKAVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A6L8HQK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriia bacterium|TrEMBL
MKIRHMLAPGSPTVSFEFFPPKEEDGFGPLFETIDALRPLSPSYVSVTYGAGGSTRHKTV
ELVKRIKRDAGIEAMAHITCVGSTREHIADVLDSLEADGIENVLPLRGDAPRGSDRFEPV
PGGFRYANELVGFIRQRYSFCLGAACYPETHPEAASPEDDLANLKRKVDAGADFLITQLF
FDNDDFLRFRDRAVGAGISVPVLAGIMPVRSLSQTQRFATMCGARIPAELLARLEAVQAN
PAQVRAVGIDHATAQCRHLLAEGVAGLHFYTLNHSTATQAIYRKIRDQLGS
>A0A441UI58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGSA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDQIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A3S3IWH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNDTTLTPAAHMTCVDAARDQVDTVIREFADMGVKRFVALRGDPAAGVGT
SYRPHPNGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A3S3D2L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFAEMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFD
GLQKDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A441UHH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPIHNFTQVGNFSARCGTLVPAWLAERFD
GLQADPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A485LJI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces stellatus|TrEMBL
MGKIIDRLKENEKTGTPSVSFEFFPAKTDDGVFNLLNRVEEMGFELQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPRDQLREILKNVRAAGIRNILALRGDPPIGSE
RWKPVPGGFHNAVELIRFIREEHGDWFCIAAAGYAEVHTEAWNNPNLPPSDQVRHLDMIR
LKEKQDAGADFIITQFFFDVDKLIQWTRDCRALGIKIPILPGYLPVQTYNSFLKFTNWCK
TSVPPQVEDALASIKNDDAAVKKYGIQLAVDTCRKLLANSLSLHFYTMNLASTVRTVLEG
LALIKHERGLPWGAPISRSKDGTWEKNIEQVRPIFWSNRASSYIARTSEWDDFPNGRWGD
RTSPAYGELSEYYLAYKRPKVARDQLWGRPETEQDVWNVFVKFIEGSVKQLPWCEQGLSG
ESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPHLM
QRLVVALADYPNLSYHAFSANGTEYTNSPGPSVTAVTWGVFPGKEIIQPTVVDTASFAAW
KDEAFELWLSQWASAYDSDSTSHHLIKNIYDNYVLVNIVDNDYTNEDSDIFKIFARVITE
GMTKDDLRQRVLELEGKNEKLHETVAKLKIIQSEANRELKDLHSELSSSREENNRLKAQL
RDMRSRLAMAEL
>A0A6J0LR67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raphanus sativus|TrEMBL
MKVIDKIQSLAEEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRANGIQNVLALRGDPPHGHDK
FVQVEGGFGCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIGENGLASNEAYQSDLEYLK
RKVDAGADLIVTQLFYDTDVFLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEVMAALEPIQDNEEAVKAYGIHLGTEMCRKILAHGTKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALTDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGNLKSSPWSELYGLQPE
TKIINEQLVKINSKGFLTINSQPSVNAERSDSSTVGWGGPGGYVYQKAYLEFFCSREKLD
AVVEKCKALPSITYIAVNKGDNWVSNTDQSDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFETWSRSWSNLYPESDPSRNLLEEVKTSYYLVSLVENDYINGNIFTVFADL
>A0A831XQZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MAENPLVDLFERIFTRTENFAKGVVFDCRHCGQCVLTPTKYVCPMSCPRQLRNGPCGGSM
NEHCEVFPDRKCVWVRIHNRQDKGGTSLPPLLRSADPKLFFTSSWLNFVRGLDGQARTPI
KYLDLGSNRKALPPQTASPLEARLKSGTFVFTSEIRSPRSGSAAFVEKRVEVLRGHFDAV
NATAFLNGHPSMPSSVASAIIAANGLDPICQMVCRDYTKTGFISELIVNAMNGVHNVLCL
TGDYYQGDPAPKQVFDMDAALMIYEARCLRETGTIAFSGDVVKDPPKPFIGGAINPYTTP
HNIPVRRIKQKCATGVDFIQTQCVLDLPIFRDFMRMYCEEGLDKELFLLAGLPVIISQKA
FEMLPGVPGVYIPDSVTQRFAGKEDIVEEGIQYAREMIEEVRAIQGVDGVHLMLFGLDHT
VLPRVVEGLREA
>A0A8C4UV52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falco tinnunculus|TrEMBL
MVNETQHTCTAGSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTDVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVMALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKVSPALLPDTLLYCP
ENCSFCSLGVRRTLLRPFTGATCPVRGCLGATTVTVLAPELWAAALPPFFHTQGQC
>A0A6N2IBL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. sk2.1|TrEMBL
MALGTPSTRTDHARTVRELLATGKTSYSFEFWAPKTERGERNLWNALRRVEAVGPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVKHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLDRFAQLSNASF
PASLKERILAAKDDPAAVRSIGIDFATRFCARLRSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A7V2Y3C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MEKKTGFAEALRQGVLIFDGAMGTEIYKHNVQSFRNFDELCVSDPGIIRGIHAAYCNAGA
DVLTTNSFGANRLALNKYGLGDRVREINAAAVALAREVAVQADRPVYVGGSVGPFLRESP
GDDVLGALREQVGSLIDAGADCILFETLPTRESAECCADAMKAWPDFPFVLSYRVFDDCE
SVAGEPLSRLMAPLPEGVPMPVAWGLNCGVGPDALLTATERAMGLIDRPLIVQPNAGRAK
EVAGRQILFCTPDYLGGYAKRYLDLGVRGIGGCCGTTPDHIKEIAQRIKPLVRNFGKTAS
IIVTSETPAKEAMAFQHKSRLAWRLANGKWATSVELIPPRGYDLGDTIRKARTLHHHGVD
AVNIPDGPRASSRLSPLITSQQIQREAQIEVILHFCCRDRNLIGMQADLLACAACEIRNI
LFVTGDPPKLGNYPFASGVFDMDSIGLCAVQKRLNQGIDLGGQSIDPQTNAAIGVGADPT
ALDFEREVRRFHEKIEAGAEFAITQPVFDLDALFRFLDRVAHLNIPILAGIWPLASLRNA
QFLQNEVPGVTVPDTIMERMASVSGKEDQRRVGIEIAREAIERLCDRVAGVQISPPFGNV
QTALSVLE
>A0A8B9K9P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Astyanax mexicanus|TrEMBL
MVNQRLDTGWQPCKSDSSGGSNSGESSKESSRCSTPVLDTDRTDRLRDKMRRRIESGDHW
FSLEFFPPRTAGGAVNLISRHFPYFTDWIVVLTYCPPSRFDRMGSGGPLFIDVTWHPAGD
PGSDKETSSMMIASTAVNYCGLESILHLTCCKQTKEIITAHLNKAKRLGLKNIMALRGDP
IGADWEEEEGGFNYATDLVKHIRHEFDDYFDICVAGYPTGHPEAESYEDDLKHLKEKVDA
GAHFIVTQLFFRAETFLKFVKDCRAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPEEI
MQVIEPIKDNDAAIRNYGIQQAVEMCRVLLASGDVSGLHFYTLNREVATMEVLRQLGLWA
EDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGEL
TDYYLFYLKSKSSKEALLKMWEEELTSEDSVYQVFTNYITAEPNKSGHKVMCLPWNDDPL
APETNMLKEELEKVNRRGVLTINSQPNINGKPSSDPVVGWGPPGGYVFQKSYLEFFTSSE
NVNALLKVLKKYEPRVNYHIVNVKGKNITNAHDMQPNAVTWGIFPGKEIVQPTVVDPVSF
MYWKDEAFALWIEQWGKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIDDMF
ELLDAPPEPLDQENLQ
>A0A7X7UI19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MAAKTLVEWIKDRVVIFDGAMGTELYKRHQFVNVCYDQLSLTQPEIVKEIHRANKRAGAD
VLTTNSFGANRRKLSGFLLGDQTFAINKAAAEVAREVAGDELLVAGSVGPLDLSVGMGGF
PEDQAISLYMESIHGLKEGGVDFIIFETFSRRENLLAAIRAAARLEMPYIPSMAVGEQGI
TRHGETIEHFYAPFPADLPAPLLLGFNCGVGPAEWLELLERFVPGSPYPVLVQPNAGLPK
FVNDRMIYMTSPEYFLTYALHFVQIGVRAIGGCCGTGPEHIHELTAGVKALHKKHVEVRE
LSREKVELREPCPTEVKSRFAWKLAHRQWVTSIEIVPPLGFDMNPTVERARACSIQGVDA
INIPDGPRASSRVSPLIAALTIQQRVGIEVILHLTCRDRNIIGMQSDLLGCAAAGISNVL
IITGDPPKLGDYPFATAVFDLDAIGFTSIAARLNRGVDIGGHPVDPATCFLIGVGADPSH
LDQKREIDRLHQKIAAGAEYVITQPIFDVDVLMRFLEKIGDLPVPIIAGIWPLASLRNAE
FLNNEVPGVTVPAWILKRMAAASASKEAARAEGIAIARELRDQIRPHIAGIQVSAPFGNV
QTALAVTAP
>D9W959|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces himastatinicus ATCC 53653|TrEMBL
MALGTASTRNDRALTVRDLLASGEQSYSFEFFAPKTDKGQHTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRATEQIATDTTLTPVAHLTAVNHSLAELRNIIGQYAGAGIRNMLALR
GDPPGDPMADWVKHPDGITYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADFAITQMFFYPEDYLRLRDRVAASGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDAAAVRSIGIDYATELCARLMAEEIPGLHFITLNHSTATLEIYKNLG
LHQRS
>A0A0Q7UJ08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Root53|TrEMBL
MADTTSPQAKLADDYSLEMTGKDVPGLHEAQDAIPQGTRVNVTFLGNEDLEMRVAAAQAV
KEAGFVPVPHISARRLASQAQLEEFLDRLQQVGATEHVFAVGGDPATPEGPYDSSFDVIR
AGVLQKYGVREVSIAGYPEGHPDIPTDVLWEHLENKAASLAEQGLGAVILTQFAFDTDPV
TTWIRDVRERGIDATIRIGTPGPAGIKRLLNFARRFGIGANAMIVKKYGFSLTNLMGTAG
PDRFVTELADLLAADPASGDVKLHMYAFGGLRATAEWARDYRHRVSA
>A0A0A8TKZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bereziniae|TrEMBL
MSKLSQYFAQNQFCCLVEYLPTKNQVLPARESLAGFPACMTLSDRVRSDEDIAPLIAAQA
YPDHIEKVLHYAGKGRDIDDFKLFLKQADSVGLRDILLLTGDKLKQHHDGQGQHARTRYL
ESVNAVMAAHQYGGFHIGVAFNPFKYTPAEQQAQYLKLHKKLNAGADYIITQLGFDLSAL
KQLQTFLAQEKYIQKTLACVMPLTLARAQFMVKHKVAGIVITPHMLEVLAQDQVNQCPEN
VYKRCALQILICQHLGYAGVHLSACHKADEQMLLEQYIEQYRDLNLSQCEILWNQLWQLA
EGEQLRPIVAAKRIKSALNNKVKYQFLDLIHRAMFQSSFMKGMGTFIFNASFWNRKTAAK
VLLQTEYLSKHYLLGCESCGQCRLAETLYICPETCPKGLANGPCGGTDLDRCEFGDRECI
HSVKSRLAHDVDQIQLLKEQLIPTVPIEVRGTSSWKNWYKAE
>A0A059FA72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas hirschiana VP5|TrEMBL
MTRPAIPSQATKDPVRVSFEFFPPKSEAMNARLWETVQRLEPMAPAFVSVTYGAGGSTRE
RTHDTVRRIAAETALPPAAHLTCVSATKEEVLAVAEEYWQAGVKHIVALRGDPPAGMGAK
FEAHPGGFADSVDLIRGLREHRPELGKCFEISVSCYPELHPENLGWDAEIAFLKAKQDAG
ADRAITQFFFEPDVYLAFLEKARAGGVTMPIVPGIMLQPNFNGLKRIAGLCGSSIPAWLH
TLYDGLDEDEETRDLVTANVAADLCRKLQAEGVEDFHFYTLNRAGLALSTCRLLGLNPQS
AKAA
>A0A286E751|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 1222.2|TrEMBL
MGSAGLRTLLDGVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLTARLAAH
GRRVVPHVPARLLRDDAHLKDVVDRLREAGVEDVFVPAGDADPPAGAYDGALPVLRRLSE
LGAPFARVGVTGYPESHPLIHDDITVQAMWDKREHATYVVSNLCFDPRVLGEWIARIRGR
GIALPVHVGVAGPVQRAKLLAMATKIGVGESTRFLTKHPSWFLRFATPGGYAPEKLLTRT
EQTLTARASGVAGLHLFTFNQIAETEAWRRALLERLGG
>A0A2H1L3T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium jeotgali|TrEMBL
MTSDPTTSDDRSRAPLDRLLSTARLEVLPTRTVTADVRAHSPQHRTVTVTASESLGLEAT
LAVACALRADGRRVVPHVAARMVSGRSHLEDIVARLHSAGVDAVFVPGGDATPGPGAYTS
SLDLLRDLARMDHPFRDIGVAAYPESHPTLSDAEVVDALADKQPFTTEMVSNLCFDPDTL
LAWIRTARDRGTALPLWLGVPGRVDAARLARVGARIGVGQSLRFLTGKVGTIARLIAPGG
YDTQRFLTRMRSALEDPTSRVAGLHVYTFNEIAKTEAWLADETATH
>A0A5C5FN02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodotorula diobovata|TrEMBL
MRISDKIKKAEREGRPWWSFEFFPPKTAEGWVNLYDRIERMQQLGPIFVDITWGAGGSTS
DATTGFVKTAHAELGLETCMHLTCTNMPTEMVDQALKEAYDSGCRNILALRGDPPRGVEE
WKPVEGGFNHAIDLVRHIRKKYGDYFDIGVAGFPEGHPQSESPEAEIRHFKAKVDAGANV
VFTQMFYDADVFIDWGRRLRAAGITIPIVPGIMPIQTYAAFKRRTDFAGTIVPQELWDML
EPIKDDDAKVREFGTRYVADMCRKILNADLGIHGMHFYTMNLSRGTEMLLEELQFVAMAD
RVKPLPWRVSLTQKRRTETTRPIFWSNRTRSYLTRTREWDEFPNGRWGDASSPAFGDVDA
LQLALPHKPQDAVKIWGTPRTLGDISALFARFCRGDLKALPWSDQPAAKETSRIAEQLAK
INELGFLTINSQPRVDGASSDDLALGWGPMNGYVYQKAYLEFFCPPQHVAPLLAILDKTP
SITYHAVNKQGDFRSNTAPGPNAVTWGVFPGAEVIQPTVVDSTAFQAWKDEAYELGAQWA
LLYQESQPETHKLIRGIFDEFHLVNIVFNDYRNEDDDAVFKPFFELAQQQQQQNGGLNGT
AAAI
>A0A5E4UH55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea aquatica|TrEMBL
MSALKQALNEGHFVCVLEVVPQQSPSRLASLAQILQRGHLAGWPLLPAFADRVGLHSDLS
PLEGADASGNPASSLLHFSGKDRERADLIRHIASMKAQGLNQLLLLSGDRLPGHHPGQKP
VRYLESVPALQIAREQCPDWLLGAALNPFKYREEEGGAQYLKAQKKLLAGADFFTLQLGF
DAAKHREAQTWMAAQPISRRMMACVMRLTEKRAAVLQNVPGIVVTDSMRELLSKEREVSP
DYASARTLERMALQIVGLQWMGYAGVHVSGVHTLDELLALEQAITVQRDSVTSLADWHER
WHASWQMPGASPVCFAPDTDAWEMGQSNVVATRSERLRYTLLSSVHEQFFNRTGWLGKAF
GWTVSQPLWKSGVAARALHAVERTLKRPLVGCDTCGHCRLQDTLYVCPETCPKGLANGPC
GGTRLNRCEFGDRECVHSVKYRIAKSVDQLPVLAHTLIPNIEAGNRHRSSWPEWFAVVDS
TPEK
>A0A5C5QWL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mandelii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A516R606|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces spectabilis|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNSLRRVEAVAPSFVSV
TYGAGGSTRAGTVKETEQIVADSTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVKHPEGLAFAAELVQLIKESGDFCVGVAAFPAMHPRSADWDSDVRHFVD
KCRAGADYAITQMFFHPEEYLRLRDRVAAAGCETPIIPEIMPVTNVRQLERLPQLSNADF
PPALKERILSAQDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHQQA
>A0A1C6G500|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Lachnospira sp|TrEMBL
MKVNEILSNGKITLSFEVFPPKTDAQFESVRQATIDVAALKPSYMSVTYGAGGNTRKNTV
AIAKGIQDTTGVTTIAHLTCVGATKENIHNTLDEMKAAGIENVLALRGDRPRDFEGDPFV
DFHYASELVSEIKAYGDFCVGGACYPEGHVEAANKSEDIINLKKKVDAGCEFLTTQMFFD
NNIFFNFLYRVREQGISVPVIPGIMPITRAKQVETARDLSGCSMPQRFLNLVDRFGSNPK
AMEQAGIAYATDQIIDLIANGINHIHVYSMNKPQIAEAIQKNLSEILK
>A0A561ELW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora atroaurantiaca|TrEMBL
MALGIPSTRTDRAQTVRDLLAAGDRSFSFEFMPPRTEAGESKLWDAIRRVEALDPNFVCM
TYGAGGSSRGRTVNLVGRIATETTLTPVAHLTAVDHSIAELRNIIGQYADEGVRNVLAVR
GDPPGDPMGEWVRHPEGVTYAYELVELIKGIGDFCVGVAAFPQMHPRSDNWDDDIRHFVA
KCRAGADYAITQMFFEVEDYLRLRDRVAEAGCETPIIPEIMPVTNARQLERFPQLSGSPF
PVELERSLRAVADDPEALRAVGLEHATAMSERLLAEGAPGLHFITLNHSTATLEIYQNLG
LHQR
>A0A2T2W9X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|filamentous cyanobacterium CCP3|TrEMBL
MGYRLRTAAQAGQFLVTAEVMPPKGGNPEHMLAMGQLLKGRVHAVNITDGSRAVMRMSSW
AAALLLQQQGVEAVCQVACRDRNRIALQADLMGAYALGVRNILALTGDPVKAGDHPEARG
VFDLESVRLLKLLAKLNYGVDSNDKPLTDGALDLFAGAAIDPQASSWSGLQRRFEAKVKA
GAQFFQSQMITDFDRLAKFMDQVASGYNRPVLAGIFLLKSAKNANFINRNVPGAHIPQAT
IDRLAAAADPLQEGVQIAAEQVQAARQVCQGIHLMAVRREDLIPQILEQGGVAPVEGAIE
AALAQE
>K5Y5V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides goldsteinii CL02T12C30|TrEMBL
MKVIDLINGSKTTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQNTDLYHEHATDLQEQVNNFNKGIAVDGSTFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVKRCRAEGIDVPIIPGIKPV
VFKNQLTVLPKIFRSDIPEPFAAELRKCKNDDEVKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMATDSVYKVAKEVY
>A0A091JRA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Egretta garzetta|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVSAGADFLITPLFKFMKDCQA
IGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSM
CRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRVEDVRPI
FWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEEL
TGEESVFDVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQ
PNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNYHIVNVKG
QNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPS
RMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A377QFM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium lividum|TrEMBL
MHRDNPKPAGNITHAYSLEVSAKDIAALSAAAPRILPGSTIAIPYLPREDDDARLAAARA
VHRLGFEPMPHLSARRIASLARFESFVQRAAAEAGVERCFVIAGDPSIPVGPFADSAALI
DTGVFERTGMKVIGVGGHPEGHPVMSKAEQWEVLERKCHNIEVRGMAPLIVTQFAFDADI
VLTWLQALRARGINHPVRVGVPGPASIAVLARYAAVCGVGACASMWSKYGVSIGKLFGTA
GPDLFVERLAAGLTAAHGKVSLHFFPFGGIAQSVKWIEQYRSRTDPGP
>A0A562BQU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus gilardii J11|TrEMBL
MGGANLIMQDRHFSFEFFPPKTPEGRDKLRNTRAQLAPLHPRYISVTFGAGGTTQQGTLD
AVLEIQRDGIEAAPHLSCVGSTRDSIRQILSTYRDNGIRRIVALRGDMPSGMGEIGEFRY
ANELVEFIRAETGDWFHIEVAAYPEYHPQARSPRHDLDNFVRKVKAGADSAITQYFYNAD
AYFRFVDDVRAMGVDVPIVPGIMPITNYAQLMRFSEMCGAEVPRWVAKRLESFGDDREAI
RAFGLDVVTALCDRLLAGGVPGLHFYTLNAAAATKAIWQRLKL
>S0NZ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus saccharolyticus subsp. saccharolyticus ATCC 43076|TrEMBL
MTDNAERQRPSLSFEIFPPNTKTSNELLLDTLDELQDLGPHFISVTCSNKNADLKTTTLK
LAGYIQKTLNVPSIAHLTAAYSSKEDIREAINILKRSNTNRILALRGDIYADKPPLEDFR
HASDLIHFIKEEEPAFQISGACHPEVHPEAKNRVEDLQNLKKKVDSGCDDLITQLFFDND
IFYRFRENCDIVGIDVPIYAGIMPIVNRNQALRLIKTTKTALPRKFIAILEKYEHDPESL
RAAGLAYAIDQIVDLVTQDTSGIHLYTMNQSQTALSIYRATKTLFKEEAIVV
>A0A1M5R1N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus nigrescens|TrEMBL
MSASVRELLASSRPTWSFEFFPAKTPEGEAQLWTALRQLERLQPSFVSVTYGAGGSTREG
TVAVTERIAAETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNVLALRGDPPGADPQAH
WVKHPEGLEYAAELVELIRSMGDFSVGVAAFPERHPRSPDLDTDVEMFVRKCRAGADFAI
TQMFFRVEDYLRLRDRVAAEGCDVPVIAGVMPVTNARQITRIVQLSGQAFPEELAARFAE
LDGDSPRHKAAVRAYGVEVATAMCRRLLDEGVPGIHFITMNRSTATREVFLNLTDPATGT
SVPSTLAGVS
>A0A6J1ZFF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinonyx jubatus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEASSGRFSVPPSIRNPAMVNEPRGDGGPTSRSEGSSS
GSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRFD
RMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCCQSREQITGY
LHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDVCVAGYPKGH
PDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQG
YHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFY
TLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMWGEELTGEESVFEVFACYLSG
EPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWG
PSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGEKITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNL
VDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A2E1XI52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvularcula sp|TrEMBL
MSYAEIHPNWETLSNDILDGYSLEITAKDVASLREAAPKIAPQTPIAVTFLPGEEMEARI
AAVKAVRELGFEPMPHVSARRLTSAKVFEDMIKRVTSESGVKRLFVIAGDPPQPEGPFED
SLQVIRTGVLEQNGIKAIGIAGHPEGHPNVSKDELWVWMENKIAEIRQRGMLPIIVTQFG
FSAEPFLDWLEEMRARGIDAPVRVGVPGPAGIKRLLGFAARCGVGASAAVMAKYGVSLTQ
LMGTAGPNKLVTAIDQGLDYERHGRVRLHFYPFGGLSKTLDWIHEFSEHRR
>A0A1Y2LES2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira alkalitolerans|TrEMBL
MTVHNDQTPRSTSDDGLRVSFEFFPPKTEKMEETMWRSIHRLAPLSPSFVSVTYGAGGST
RDRTHSSVTRIQGETGIPAAAHLTCVGHTKEEIETIARKYWDEGIRSIVALRGDLPDAGD
KYVPTPGGYPYAVDLVEGLKRIADFDISVSAYPETHPDAPNADFEIDYLKHKIDAGANRA
ITQFFFDNDVFLRFRDKCVAAGITAPIVPGILPVTNFGSLLKFANMCGASVPKRWHWRFE
GLDEDPETRRMVAFHEAISQVEGLMKEGVTDFHFYTLNRAELTYAICHALGIRGTAKAAA
>A0A0P6X115|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolinea tardivitalis|TrEMBL
MVTAEVAPPISASAADLVKKVTMLKDYVDAVNFTDNPSATPRMSSLASAALCLQSGVEPV
MQITARDYNRMGVQSAVLGANALGIRNILCLTGDHSRLGPEPHSRMDIWDLDSVQMIWLL
RRMRDEGHFLDQREIKEPPKLFIGAASSPNASQPRFQIIRETKKANAGAQFFQTNLIYDV
DAFKSYLDLLDKAGLLNRVYIMAGVTPIRSAKAARVMNTIPGVKIPQKMIDRLENSADPK
EEGVQIVLELISGMKDFPINGIHFMAVGWESIVPRLITESGLQDRRMGM
>A0A317PK99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea marina|TrEMBL
MSMSDVNPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAAVF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAAMG
VSNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRIMRDNGKFLSGRKLTTPPQVFLGA
AINPFAPPYDFRPHRLAKKIAAGAQFVQSQYCYDVPMFRSYMQKVRELGLTEDCFILCGV
GPLASARTAKWMRANVPGVHIPDHIIARLEGAADQKKEGKQICIDIINEVKEIEGVSGIH
VMAYRQEEFVAEIVHDSGVLKGRKPWRKEPNPANALAEAHLQEAAEQPRMTPHAMAGVAA
ESNEPN
>A0A2X2YVR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter koseri|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFD
GLDDDAETRKLVGANIADGHGEDLKP
>A0A0P9VKZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas meliae|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>F7QIR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobiaceae bacterium SG-6C|TrEMBL
MTSDTAAPAEPHGHKRPAISFEFFPPKTEDMERGLWEVINRLAPLTPNFVSVTYGAGGST
RERTHATIARILAETKLTPAAHLTCVAASKADIDDVVARYHDVGVRHIVALRGDPTSGIG
TQYTAHPDGYQQSSDLVASIKRNHPDMEVSVSAYPEKHPESASLDADIDALKAKVDAGAT
RAITQFFFDNDLYYRYLDRVRAAGITIPIVPGILPVQNFKLAKNFATRAGATIPDWLEAK
FEGLDDDADTRRLVAATVAAGQVQKLAKQGVENFHFYTMNRADLVFAISHLLGIRPAGAQ
KAA
>A0A4Q4NP11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria alternata|TrEMBL
MERITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCIGVAAYPEGHSDQSHPQHQDPQFDL
PSLIEKTKAGADFIMTQLFYDVEAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTTLSHAKLPSDMLARLDAVKSDDELVKQEGVKIMDEMVEHIKARPDTCRRGFHFYTLNL
EKAVSHIVEDTHLIPSTIDDNDDVIVETTPAINLEPPPNGFVPHRRRSSAVNSGPRNRVI
ISHSSAAKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKDDISKLFRRHIEGDLEAIPWSEQSLSP
ETLTISKQLLALNAKGWWTVASQPAVNGVKSTDPVFGWGPKNGYVFQKPFVEFFIPASEF
AALKPKLDAHEQVTYFAGNAAGEFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIFQEWQRIYPPRSATSTLLGALRRDYWLVNVIWGDFVQGEGLWEFLEQ
>A0A4Y9EMX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polymorphobacter arshaanensis|TrEMBL
MTLTQAEKYEAARAHGTPLFADLPGDIDISFEFFPPKTPAMETTLWESVQTLAPLSPRFV
SVTYGAGGSTRERTHATVERIARETDIKPAAHLTCVDASREEIDAIARGYWDAGVRHIVA
LRGDPPRAGEKFVARPDGYASAAELVEGLKRVADFELSVSAYPERHPDAATATADIENLK
RKIDAGAVRGISQFFFEPDTFFRFRDAAAAAGITAELVPGILPVSNFAMLKKMAASCATH
IPDWMGRLFEGLDDKPAARQLVAATVAAEQCRRLYAGGVRQFHFYTLNRAELAYAISHML
GVRPKVSEGQ
>A0A2S4TL09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. ASNIH8|TrEMBL
MGFHSARQVEALNQSLADLGGDISVSFEFFPPNSEGMENTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLENDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQA
>A0A8B5VV14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus avium|TrEMBL
MSSTLSFEVFPPNTQVGTEKLITTLEELQQLAPDFISVTCSNNRQTIEETTLRVADYIHT
ELQVPTIAHLPAAYLDQAQVQRLVTRLDQIGIHQILALRGDIIPELPPKKDFTYASDLID
YVKQQAPHFHISGACYPETHPESQNRIEDVKNLRRKVAGGCDQLITQLFFDNELFYQFQE
SCDLADIKVPILAGIMPIVNRKQALRLIKTTNTKLPRKFLAILEKYEHDPIALKEAGLAY
AIDQIIDLATQDVAGIHLYTMNNAEVAKHIYYNTKNVLKGQIEVR
>A0A7C6RND6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epulopiscium sp|TrEMBL
MKLSQIYSSDTRRLSFEIFPPKTDIPIDTVFDTISKLKQLNPSFISVTYGAGGSNKGRTV
EIASKIKNEHGLEAMAHLTCAGHTKEDIDYILEELKQKGIENILALRGDPPTNQPNFDYH
KNDFPYAVKLIEYIKSKGDFSIAAAAYPEGHKDSKSITKDWYYLKEKVDAGVDVLITQLF
FDNRIFYHFMEDIERIGIRCPVIPGIMPIFNSKQIKRIISLCGSSMPGELLTMMDQYGDS
QDDLRKAGIEYAIRQIQDLLDNGVLGIHLEPMNRPALAEEIIKGLSYKFN
>A0A5E4PX65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptidea sinapis|TrEMBL
MEKITELIRNLNEFSFSFEVTPDVNRGDLDGLNIKPLFFSITWHAKKYEMTDLNIPPIQL
AEFLRDKQKNVLLHLSCDRLRRAYLNKLLDHLKAKEICNLLLVRGEGYDSSSSDFKSTSE
LITHVRQYSGNYFCIGIVGHADRNDRYQSLKLKVDAGADFIITQAFFDVNVYKIFVSEAK
KLNINIPTIPGLFPFETREELDGFINLCKVHVEENLIEKLVTNTGVTSIKDIATGMYKAM
H
>G5JTZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus macacae NCTC 11558|TrEMBL
MSRLLERLKTDILVADGAMGTLLYADGLEACHEYYNISHPEKIISIHRAYIAAGADVIQT
NTYAAKRHRLKGFGYDHKVEEINREAVALARQAAGDDLFVLGTIGASRGLKQCDLTLDEI
VSETVEQAKILLETRQIDGLLLETYYDLDELIAALKALRPLTDLPIITNMALYEAGITES
GRPLVEAFSHLVMLGADIVGLNCHLGPYHMIQSFKQVPLFAQSYLSAYPNASLLSFSNDD
EKGHYSFSQNADYFERCAKLFVEEGVRLIGGCCGTTPDHIKALKRGIRGLKPIEKKVTLP
PADPEEPIFETEKKESLVDKVKREVTIIAEIDPPKTLAIDKFVEGVKALDKKEIAAITLA
DNSLARTRICNLSMASLMKEEVETPFLLHIACRDHNMIGLQSRLLGMDILGFDHVLAITG
DPSKIGDFPGATSVYDATSFKLLNLIKQLNQGKGYSGASLKKATHFTVAAAFNPNVKNLS
RTSRLIDKKVAAGADYFITQPVFNAKTIVGLKEVTQNYEQPFFIGIMPITSYNNAVFLHN
EVPGIELSEEFLARLEKVKDDKEICQELALAESKRLIDSALESFNGIYLITPFMRYDLTA
DLIDYIHEKSMTIQEKRA
>A0A4R1C108|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides jejuensis|TrEMBL
MTQATRSIAERIRSGERSISFEFFPPKDEAGETQLWQAIRELEDYRPTFVSVTYGAGGST
RDRTVDITRRIVDETSLLPMAHLTCVGHTKDELDEILAAYADAGVANVLALRGDPKEGPR
ADWTPTDGGFEHAVELVQLAAAKGGFSVGVAAFPEGHPSAASLDHDAEVLVEKARAGAEF
AVTQMFFDAKDYFALVERVRAHGVDMPILPGIMPILNLNAIAKQGELIGTSVPEHVVATF
DGLTEPAEIRANGIRLATELCRELLDGGAPGLHFYTLNRSKATREIFEALAALQA
>A0A4Y8HYH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium MT.SAG.3|TrEMBL
AFYSVTYGAGGSTARPTLELVCKIQDEFGITSMPHLTCVNHSKEYLINYVQELKEKGINN
ILALRGDMPGGNNFVPHPEGLRFAADVVGLVGELNHFCIGVAAHPEGHPDASSLEEDIKY
LKIKLDAGADFAITQFFFDNEFYFKFLKMARNIGIVKPIIPGIIPFINSNHVMKFAKMNG
THIPDLLKEQMVEAGDDRERSSTLGIEQAVKQCRELLDSGVPGIHFFTLNNSKPTLSVLR
KLLII
>A0A423PHL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinisphaera halophila YIM 95161|TrEMBL
MTPFCNEKRREPAGASAPGGTADEARRVMTAEQALSRALRRPRYEIIPMRGALEAARALP
AHAVVTVTCSPTRGIDATVELAAQVAALGHVAVPHLAARRFSSRSHLETGMSRLTEAGVR
DVFVVGGDGDHVAGPFDHGCRLIEALAEIAPGLRSVGVPCYPEGHALIAAETLDEALDAK
CFLAGHMVTQLCFDAARIRDWLQGARGRGVGLPMHVGIPGVIERRRLLGIALRIGLGDST
RFLRGNKRMWGRLTGPSQFTPDALLDDLAPLLAAPELNVAGLHINTFNQVDSTEAWRRKR
LSTLASTAGDVGVSGSPSSAAPDGRA
>A0A329Q2K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas elongata|TrEMBL
MKFDDEPVPGYSLPVLPGHVSPGRLERVLRAGRFAVTTEIDPPDSADPAEVLRRAAIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYATILQMSCRDRNRIAMQGEILGAAAMGAC
NLLCLTGDGVQAGDHPHARPVFDLDSLSLLEMARRMRDESCFESGRPIDSPPRMFLGAAA
NPFVPPRAWRAQRLAKKVAAGARFIQTQYCFDTAVLRDFMAEIADLGLLEGPDRIHVLVG
MGPLPSARSARWVRDNVPGIHIPDSVIKRLEGAQNQREEGARLCRDILQEVREIEGVSGA
HIMAYRQEATVARIIEETGVLEGRVPWYPGRDDPTELNPEAPDAAGDLPAAASS
>A0A6B1YBH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKSLQLPR
>A0A125V3H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridioides difficile ATCC 9689 = DSM 1296|TrEMBL
MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAANVTDFQSAVMRATSLA
TCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLLALTGDHTSVGDHPQAKGV
FDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTPEYSPIEVQLLKMKKKIKAGA
KFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSPGMAKFMTANVPGIFVPDEQIER
LRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIMAIGAEENIPAILDAAGL
>A0A2T7BKX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga parva|TrEMBL
MKITEHIAAAAGKKQTPISFEILPPLKGKSIESTYDHLDPLMEFKPSFVNVTYHRSEHMF
KKRPDGTFEKVEIRKRPGTVGICAALMNHYKIDAVPHLICGGFTREETENALIDLGFLGV
DNVLVLRGDAPKNESFFEAEPGGHRYAIELLEQVANMNNGVYLEKDLQGGVKTNFCIGVA
GYPEKHSEAPNLQIDLEFLKKKVDAGAEYVITQMFFDNQKYFDFVTRCRAAGINIPIIPG
LKPLTSKKQLTTLPPIFNVDIPSDLALAMMKTKTDKEAEQVGTEWLIAQSKELKAFGVPV
LHYYTLGKPMVVRDAVAAIV
>A0A4U0RE36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus gahaiensis|TrEMBL
MTPPKISFEFFPPKTLEASFKLWEAARVLAPLAPEFVSVTYGAGGTTRQLTHEAVTTINR
QFGLQVAAHLTCVEATKAETMEIVQSYADAGIREIVALRGDAPKGSDGFVPHGDGFANSV
ELIEAIAARGDMTIRAGAYPEPHPDSPDGDADVAWLKRKIEAGASSAITQFFFEADTFFR
FRDKCAAAGIDVPIIPGILPVQSWAGTKRFAATCNTTVPDWAEEAFQMAALDGPEAQRTL
ATSLSVELCEALIAGGVDRLHFYTLNRPELTRDVCAALGVRPAGSLDAVA
>A0A1A9NJK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacillus sp. MM3|TrEMBL
MNNTPVISFEFFPPKTAEGMTKLHAAREQLAQLRPKFFSVTFGAGGSTRDRTLETVLEIK
ARGTEAAPHLSCISSTRDEILAILTQYREQGIRHLVALRGDHPSGEVAASDFHYANELVE
FIRKETGDWFEIEVAAYPEFHPESPSARADLEAFKRKANAGANAAITQYFYNADAYFRFM
DECTAMGISIPVVPGVMPIYNFAQLSRFSAVCGAEIPRWLRLRLQDYGEDLPSLRSFGLD
VVTELCDRLLQGGAPGLHFYTLNQAGTISTICQRLGL
>F4LVP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidanaerobacter acetatoxydans (strain DSM 21804 / JCM 16047 / Re1)|TrEMBL
MGLKEKLEHNEFAITAEMAPPKGIDFGRIRECAQAVKGRVDAVNVTDFQSAVVRSSSLGG
AKVLLEEGLEPVMQITGRDRNRIAIQGELLSAAALGIKNILALTGDHPSIGDHPEARGVF
DMDSVGILQAATKLMNGEDFNGHELSGIPEYFLGASVTPLYEPVELQIIKMVKKIQAGAR
FFQTQAVYDIDVIKGFMDKIKDLDAKVLVGVIPLKSAGMAKHMNNNVPGIHVPDEIIDKM
KKAQDKEKEGLNIAAEFIKQVREEKICAGVHIMAVGAEENLPVLFDMCGF
>A0A1G1FI13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium GWF2_44_13|TrEMBL
MSFKDILNSGKFVVTAEVGPPKGTDIKEMLHHMEILKGKVDAVNVTDNQSAVMRICSMAV
SRTAMEHGLEPIFQMTCRDRNRIGLQSDLLGASILGIKNVLCMTGDHVSAGDHKGAKPVY
DVESVQLLKIVDGLNNGKDMSGNELKGSTDFFQGAVVTPEANPIEPQLIKFEKKIRAGAK
FFQTQAIYDIEKFKDFMKHARKFPVKILAGFVVLKSAGMANFLNNNVPGIRVPQVLIDEL
KAAGKEKALDTGMNITARHIKQLKEEKICDGVHIMAIGMEDKVPEIMERAGLP
>A0A533VGG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MDVKVIYEMNPPKVLYNNYFDHDTINKNIDLFMSRAKKISEFVDGIHLTDNVLGVPRVSS
LMLVSMLKRLGISKPISCTCRLYDKNLISIFQFVSEAIFCGVYSILILRGDEPIIGNKNF
DIPPTKIVRILSSHSFNNYIKFDLSVPSKISDTAKIKNKLEARPRAFVTQSISSIHNLQE
IIKMSAPYGIDVIPCIMCPSKRNEISAQKIGLDWRSYRDEPENFVREAATLTEKILLCSP
NSFEDGLDLVMKLKES
>A0A6I7QU27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MQEHLETGSYHVEILPPKQETEKIYADLDLFKNKYVRVMGSGYCACITDNAMGNLAFQGT
EIIEELELEAPDRQVMIHLNTFHTKADLHRILDSCKSAGIRQLLVITGDGSDRLPRLAPA
EVGAEGVEAVTSVELLKYIKETYPGDFDLGVAFNPYEPEDHEFAKLDRKLAAGATFAITQ
PIIERHPVVDRLLKEYPDLPVVIEAWMSKKISLLSEAVGYEIPEDTPYDPMENLKILHKN
YPNCEVYLSILGFKTQYDRLPEVRNN
>A0A3N5U915|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
GTMLYERGIFFNRCFEDVNLAQPEMVQAIHEEYIAAGAEVIETNTFGANKYKLARYGLEE
RVQAINKAGVKIARDAVAAAACIAAGNSPGDNLKARNDIFVAASVGPIGCRIEPLGVLSR
QDAVRIFKEQLSALLDAGVDLVVFETFKNIDELVLAVETLRSLSADIPVHAQFTVGSDNT
TEEGIPALKAAALLSQHKGIDVVGINCSIGPASSLDVLLSFRGHVHKPISVMPNAGLPRE
HEGRLFYLATPEYMAEYAKQFLDAGAAVIGGCCGTTPAHIREISHTIKNFDRGRRSIAVT
PIKDDVAEKPEKPLSQRSDFGKKLSTGEWVTSVELVPPQGTSLKPILEKAAELCRVGVTI
VNIPDGPRASSRISTMITAIEIERQTGMQTLMHYCCRDRNLIGMQGDLLGANAVGLHNLL
IVTGDPPKVGGYPDVSGVFDVDSVGLTRLVTRLNHGVDLGGNALPSTTAFVKGTGANPVA
TALDREIERAYRKAEAGADFFITQPVFDIKAFELFMKKIEKLKLPVIAGVWPLASYRNAL
FMQNEVPGVVIPESIMKRMEKAPDKDKARREGVVIAREMIKEMKAVIAGVQVSPPFGRVK
TALAVMAKDDAEMEAMLK
>A0A1Y3AT29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euroglyphus maynei|TrEMBL
MLEPKYSIDEKSYVSLAEKIRQRSSSHQHQQQQCDRFFSVEFFPARTAQGATNWLRLVEK
YADGNPLYCDITWHIAGQPGSDSPTSSLTMANVALNYCQLETMLHITCIGLTREQLQQHL
ERAKHYGIRNILALRGDRHGKC
>A0A2D8WZ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp|TrEMBL
MTRTAPKISFEFFPPKTLDASFRLWEAARALAPLNPDFVSVTYGAGGTTRKLTHDAVTTI
NRHYGLNVAAHLTCVEATRAETMEIVQSYADAGIREIVALRGDAPKGQDRFTPHDDGFVN
SVELIEAIAARGDMTIRVGAYPEPHPDSADGDADVAWLKRKIDAGATSAITQFFFEAETF
FRFRDKCDKAGIDXPIIPGILPIQGWAGAKRFAQSCGTTIPAWAEDAFAAAIRDGGDRER
LLATAICAELCDTLIEGGVDRLHFYTLNRPEMTRDVCAALGVQPVRELEAVA
>A0A2T7UX81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararhodobacter aggregans|TrEMBL
MSLFWSDPNAIRPYEAPPPGHVAGSKLEIALRAGQFAVTAEMNPPDSADPADVFEAAKPL
ADVAHAINATDASGANCHMSSIGICALLTRMGHGTVYQISCRDRNRIAIQGDVLGAAAMG
VKNVLCLTGDDVGAGDQPGAKPVFDLDSLTLIRTIRTMRDQGVFLSGRKITKPPKLFIGA
AENPCVDPVEWRPERLAKKVEAGAEFIQTNYIFDMPRFEAFMARVRDLGLEKRVFILPGV
GPLASGKAARWMRSNVPGIHIPDAVVERMEKAANPGDEGRRICVELIQQIREVKGVAGVH
VMAYRREHLVADILREAGVARDERAENAQL
>A0A501Q8F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium microcysteis|TrEMBL
MKVTEHIEKANGKSLFSFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYEYKE
LPSGLLEKKIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VVALRGDAVKNETYFKPEKEGNHYASELVTQITNLNNGIYLDDELQNSSATNFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGASYIITQMFFDNKKFFDFVAKCRKEGITVPIIPGLK
PISTKKQLNLVPHRFKVDIPDELIMAIVRAKDTEAVKQIGIEWCINQSKELIKQGIPVLH
YYSMGKSENIKAIAREVF
>A0A1X6YQ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius gaetbuli|TrEMBL
MKTPRISFEFFPPKSLEGSFRLWDTVQTLAPLEPRFVSVTYGAGGTTRELTRDAVGTLHK
ATGLNVAAHLTCVDASREETLEIADQFAAAGVTEIVALRGDPPKGANGFAPHPQGFGDSC
ELISALADTGKFNIRVGAYPEKHPEAASQQADIDWLKRKIDVGASEAITQFFFEADTFFR
FRDACAKAGINAPIIPGVLPIENWTGTRKFATACGTQVPAWLDDAFDKAIRDNRHDLLAT
ALATELCSDLIEGGVEDLHFYTLNRPELTRDVCHALGVTPRVELRHVA
>C4FEQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium angulatum DSM 20098 = JCM 7096|TrEMBL
MTAPLFSLEVFPPRRNAPVGTIYDTLDGLQGLAPAFISVTYGTGKSKDRTATARIANTIR
GEYGIPAVAHLTAQYLDKEAADVALDLFEVAKVDGVLALRGDSVEGQTPAGVFEYASELV
SYIRENRPQLKIYGACYPEKHPQAATIDEDVDNLKRKVDAGVTHLISQLFYSNDDFYRFL
DKAREAGINVPIEAGIMPVTNAKSVRRMSATCEARVPEPVEAMLQRWGDEPAALREAGIA
YASQQVADLIAHGVDGVHLYTMNHPAVTRRIWNNVSALFQS
>A0A2N7BD98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Siphonobacter sp. BAB-5405|TrEMBL
MKVTEYIQQANGKALFSLEIIPPLKGQSVTELFDTIEPLMEFKPPFVDVTYHREELIEKR
HPSGLIQKVPVRRRPGTVGVCAKLMERFKVDAVPHVICGGFTKDETEDFLYDLHYLGINN
VLVLRGDPEKSAGVFKPKEGGHAYATELVEQVVDMNHGRLLHEETEAQPTNFCIGVAGYP
EKHFEAPNHSNDLRYLKKKVELGAEYIVTQMFFDNQKYFDFVKRCRKEGIMVPIIPGLKP
ISTKKQLTVLPRIFHLDFPEELVHAVEACKSDKEVREVGIEFGIQQCKELLDFGVPVLHF
YTMGKSDSVQRIARAVF
>A0A2G7RVN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. LMG 10879|TrEMBL
MTAISFEFYPPKTDEQRTQLDRAAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAQDALLDLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VQRLGVQVPITPGIMPISNFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGAEVV
AKLCQRLVEGGAPGLHFYTLNLAKPTVSVLTLLRG
>A3VMM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritimibacter alkaliphilus HTCC2654|TrEMBL
MSMFYSDPNAIRPYEPIPEGHKAGSVLERTLRAGEFAVTSELNPPDSADPEDVFAAAKPL
AEVTDAINATDASGANCHMSSIGICSLLTRTGHGSVYQISCRDRNRIAIQGDVLGAAAMG
VRNVLCLTGDDVGAGDQPGAKPVFDLDSVSLIRLIKTMRDEGRFLSGREIAKPPRLFIGA
AENPCVDPVDYRADRLAKKVEAGADFIQTNYIFDIPRFERFMERVRDMGLDKRVFILAGV
GPLASAKAARWMRSNVPGIHIPDSVIDRLAKAEKPGDEGRRICVELIQQVKDIAGVSGVH
IMAYRREHLVADILREAGIARPQKQSA
>A0A2T4D9W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. Z-F4-2|TrEMBL
EHGINRIVALRGDMPSGMGAAGELRYANELVEVIREHSGDTFNLEVAAYPEFHPQARNAE
EDLKNFARKVQAGANSAITQYFFNADSYFYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRF
SDMCGAEIPRWIRKQLEAYGDDSDSIRKFGEEVVTEMCEKLLKAGAPG
>A0A6N7NYI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. MY15|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAARLKDYDPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGTAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
AKLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A6H3S6W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. 116-D4|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQDLAPHFISVTASNNKFNIKETTVRLADF
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIREQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNSAETAKYIHQATHALFNHQSLG
>J7W2I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VD142|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINRAAVNIAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTSIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPNFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A838VBA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium|TrEMBL
MNLSLSQLEEARRALNAPLFADVAGDIDVSFEFFPPKSEKMAETLWESVQTLAPLGPRFV
SVTYGASGSTRERTHATVARIVRETSVPAAAHLTCVDASRDEIDAVARDYWAAGVRHIVA
LRGDPPVAGARFEAHRDGYANAAALVAGLKAVAPFEISVAAYPEIHPDSANGQADLDNLQ
AKLDAGADRAITQFFFSPEAFFRFRDRAAAAGIDAEIVPGILPVSNVAQTRKFAGLCGAA
IPPWMDRLFEGLDDRPAARQLVAATIAAELCRRLYAGGVRHFHFYTLNRAELSYAICHLL
GLRPTAAAREEAA
>A0A7G5H3N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma sp. KCTC 72228|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFTREETEDFLIDLHYLGID
NALVLRGDPAKPFSTFKAKENGYSYASELVEQVANMNRGIYLHEEDTPLAPSNFCIGVAA
YPEKHFEAIDHDIDFHYLRQKVEKGADYIVTQMFFDNQKYLAFVNRCRQEGITVPIIPGL
KPLSTRKQLQILPKLFHLELPEDLVKAVEACENDQQARQVGVEWCIQQCRELTAAGAPVL
HFYTMGKADNVMKIAREVF
>A0A8F6HCQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas indicatrix|TrEMBL
MTAISFEFYPPKTDEQRTQLDRAAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAQDALLDLKHFKAKVDAGADAAITQYFFNPDAYFHFVDE
VQRLGVQVPITPGIMPISNFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGAEVV
AKLCQRLVEGGAPGLHFYTLNLARPTVSVLKLLQG
>A0A3D3BET4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp|TrEMBL
MSPDINPHDPGAPLAPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYDRAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAMQGDVLGASAMGV
QNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDEAKFLSGRKLTTPPHVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLHKKCFILVGVG
PLASAKTAKWIRSNVPGVHIPDSVIARLEGAADQKREGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWQREASPGDALVAERLEQIREEKVENQQQLAGIAAQ
HPH
>A0A415QM62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricimonas virosa|TrEMBL
MKVIDILNKSDKAVFSFELVPPLKGGDINKIYEAIEPLIALAPPFINITFHRDEVVYREY
PDGTIKKVTVTKRPGSVALAAAIMRRYNVDMVPHIVCGGATRHKIENELIDLNFLDIENV
MALRGDPIPGERFFTPEEDGHQYSCELVEQITRMNHGQYLDDTLTEAVPTNFCIGVAGYP
EKHYEAPNQACDIENLKKKVDAGANYIVTQMFFDNSKFFQFVDKCRAQGINVPIVPGLKP
ISTFKHLEMLPRTFSIDIPHELVKEIRSCKNNKEINQVGIEWCVAQSKELIAYGVPAVHY
YTMGKSENIQEIVKQVF
>A0A349ND57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MFDKKSKFLFTAETTPNISTDLAASAGRIDELVNLADAVNVTDSPNCKVRLSSLLVASAI
KAKGLDVVLQVTGRDRNRVALESEILGALSVGINKILCLSGDQPGTGGPVVVNELNSLGL
TQLCQQISGGALTDGTKIDGPAKIYAGSADDIYSHLADPSARNRLLAKVENGSTFIQTQY
CFDLATIEEYAKQLTEHTQFQDCAFLVGMGPLASAKQADWMRKNLWGVHIPDPILQRLEE
SKDASKEGETICEELIEKMMDIAGISGVHLMGPNCEKRSARIISRFVRGQDLNAQS
>A0A5C7TWS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp|TrEMBL
MSSRSESRRDDLRISFEFFPPKSEEAEQQLWNTVADLSDWEPEFVSVTYGAGGSTQAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLAAGVRRFVALRGDPPGGVGTAYRP
HPGGYANAAELVGALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKAENGADRALTQF
FFDNDAFERYHDRVRAAGIDIPIVPGIMPIQNLTQLKRFAGACGASIPSFLDERFDGLDD
DVEERAKVAADVAAEQIQDLMRRGIHEFHLYTMNRSPLVSAVLERLGLQRRADARAGAAA
>R4V6Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spiribacter salinus M19-40|TrEMBL
MKTVLEAVPPERHRGEAAVEAVIEKVAQVHAARPLDRVNIPEIHEEPARSQKGERRKPFE
PRMAPRALGQLIQERLGIPCMINHVVVHQRSADLLDWCRETWSEYGIREFVLVGGGLADT
VYPGPTVPEASQLMRDALTIPELRVGNICIPSREDEAARMAAKTAAGADFFTTQILYEPD
HFTHLLDEMARIGETADEVLLAFCPVRSLRNIRFLLWLGVSIPDALEAWLTEVDDAVPQR
SLEQIRRTWADIIDHQREAGRPRPRLGVNLAPIGAVAPQTTIGLARDLAAMHDQSLNAV
>A0A1T0CXE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella porci DSM 25326|TrEMBL
MATHSVSERTTKAKTPFSFEFFPTKTDEGQDKLLGVFDELNALNPKYFSVTYGAGGSTRE
RTLGIVKALIEKGSTPIAPHMSCIGDTKSQIGELLDYYKALGVDRVVALRGDLPSGQVGY
GELPYALDLVKYIREHSADHFSIKVAAYPEMHPQARNFEADIDNLVAKYHAGANEAITQF
FYNPDSYLFLRDRLTKKGVHQDDFPIIAGIMPITNASNLIRFADGCGADVPRYIRKQLAD
YGDDKKSIRQFGFDIVHQLCERLISEGVPSLHFYSMNHTEPNKALVESLGLI
>A0A4Q7IYD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis suaedae|TrEMBL
MTSVVERLRGDRTAFSVEFFPPRDEADEAILWRSVRELEGYDPAYMSITYGAGGTSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGEWI
PHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSADLDADTKYLVRKLNAGADFAIAQ
LFFEADDFLRLRDRVAATGCEAMVIPGIMPLTTPRTLRKTIELSGAQAPRWLLDRLEPLS
GDAKAFRAEGLDVVTELGERLIAEGVPDLHFYTFNRSKATRELITRLNLVPARVPPG
>J2URG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. GM01|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRGIARDYWDSGIRHIVALRGD
LPPGSGKPDMYGSDLVELLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMSAMFA
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAIGG
>A0A353GBH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp|TrEMBL
MADNSQKKVQARPFKLSFEFFPPKSEDMEAQLWETVDDLAGWEPEFVSVTYGAGGTTKAP
TLAAVRRLIAETPLATASHLTCVGATREEVAHVVAEFRAVGVNHFVALRGDPPTGVGSAY
QPHPGGYENAAALVAGLKDMGDFEISVSAYPEKHPESADLAVDIDMLKRKVDNGATRALT
QFFFDNDVFERYLDRVRSAGISIPIVPGIMPILNLTQLKRFASMCGTSVPAWLDARFAGL
DDTPSERARVAAAVAVEQINDLRRRGVDEFHLYTMNRAPLVNATLHQLGLSRRNRRDGID
APRAVGASA
>A0A365ZKV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PT12|TrEMBL
MALGIASRMTGRAPTVRDLLAAGERSYSFEFSPPKTERGERTLWSAIRRVEAVGPTFVSV
TYGAGGSSRERTVRATERIAAETTLTPVAHLTAVNHSVAELRNIVGQYAGAGIRNMLALR
GDPPGDPMGEWTRHPEGISYAAELVGLIKESGDFCVGVAAFPEMHPRSTDWESDIRHFVA
KCRAGADYAITQMFFYPEDYLRLRDRVAAAGCETPIIPEVMPITSVRQIERFTQLSNTTF
PPDLERRILAVKDDPMAVRSVGIDFATELCARLMEEDIPGIHFITLNTSVHSTATLDVYK
NLGLHQRT
>A0A374HZ24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. TF12-2|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A520Y186|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium|TrEMBL
MARTRISFEFFPPKSLDASFRLWDTVNTLAPLDPGFVSVTYGAGGTTRDLTHDAVGAISR
NYGLNVAAHLTCVDATRDETRAIARRYADAGVREIVALRGDPPKGAGSFEAHPEGYATSC
DLIEDLADMGDFHIRVGAYPDRHPEAASDTADLDWLKRKFEAGAGSAITQFFFEAETFFR
FRDACQKAGIDAPILPGILPIENWAGVQGFAQRCGAAVPGWLADAFETATRDGREDLLAT
AVCTELCSELIEGGVEDLHFYTLNKPTLTREVIHALGLAPQVALEKVA
>A0A364NC80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stemphylium lycopersici|TrEMBL
MHISQKLAQAKAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALRDAYQAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIREKYGNHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGGTF
IVTQMFYDTDLFLEWVRKVRAKGIDVPIVPGIMPIHTHAAFLRRAQWTKCNIPQSWTEAL
EPVKNDDVEVREVGKHLIADMCRRLIEAGITHLHFYTMNLAQATRMVLEELDLLPDVESP
LEKPLPWRPSLALNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPMSIRDLSNLFVRYMEGKLDSLPWSEQAITTEAGSIQNDLID
LNRRGFLTVNSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDVVDTWYLVNIVHNDFHESRGIFPIFDGLEVKDMDKPLHNPSADI
PGVNGSEAANGTNGVPDTNGSKSEQAGPRKEENPSLIDAAKAAAVDVTNGITGLAASN
>A0A1M4LBY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella sp. 10RB9215|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A807AQ66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium ciceri biovar biserrulae|TrEMBL
MNDMRQELIQTRGSATFAFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLEICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A806FX31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus rhamnosus ATCC 8530|TrEMBL
MKISQCFKDHQVISFEVFPPRKNATNIAMRPILNTLDAVKAADPDFVSVTFGASGNKPHM
GTLEVAKLIKDEFNLEPVAHLPAAQLTRAQVDAELRGFQEAGIDNILALRGDIPKSGRVS
EDFPYACNLIEHIHQVGDFDVVGACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYQFRERAALAGINVPIEAGIMPVINEHQIERMATMAGVHLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A846MHI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium vermicomposti|TrEMBL
MTLSFPSVEEARRALEAPLYADLAGDLNVSFEFFPPKTEKMEDQLWSAIETLTPLGPKFV
SVTYGAGGSTRERTHNTVARIARETSLQAAAHLTCVAASRAEIDDVADCYWEAGVRHIVA
LRGDPPEAGTKFVPHPDGYQGAAELVEGLMKRHPFEISVAAYPETHPDAASAQSDIDNLK
RKLDAGATRAITQFFFEPETFFRFRDTAAAAGITADIIPGIMPVSNFGAVQRMSAMCNTD
VPGWMGKLFEGLDDLPAARQLVSGTLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPAGLEKTA
>A0A7X7D981|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MVHTGFSSEVVWEVDPPADGDPRSLSAQLDAIGDVVDSVLVPDNHTGRATVSSIAVARRV
REHGLRPVACLNARDRNLLGLRRDLITCAFEGVDDVLLVYGDDPSVGSRAGDLTVRQMLD
ECRTQAPQLRVGVTTRLSRVPQWKLSADRLFVQVSYDLDAIRAWRDAVDFDGPVIPAVMV
IPSVPMAERLAARVPELRVPSPWLDAIASDPAAGTELAIDLAERILDTGEFAGVHIVSGR
QHLATAARLRSRSTSRSRCPVAV
>A0A6G2JSH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MLLLKDASGRRRLLQHAQWELIPLRNLAEQLPHLPPQSPVSVTASASKTLEDTLDLTAEL
CALGHHPVPHVAARMVTSRDHLEELLGRIESMGLSEIFLVGGDVASPAGPFDSAVGLLEA
LREISHSLVHIGVTSYPEGHALITDAVLHEALHVKQVLLAEAGIEGHAATQMCFHPKAIL
EWLAAERDSGLNLPVHLGIPGAVDPARLLRIGTRLGVGASLRYLRKNTGAVARMLRPGGY
DPSGLVDRIAPHAERLDIAGLHVFTFNAIADTVAWRESALAETSSRRR
>A0A8I0AGJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. BX17|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMENLPGTIDHLMKYKPEYISCTYGAGGGNVGANRE
VCQMIKKAGTVPVTHFTVIKNTKEGIKEQLDQYLAEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDMSATINMALSRNGCVMDSELCRLISRNWLFPN
PFAAKDADGKPFDMFYDDKIKRFKEEGIEYTIKQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A7Y0HUW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium sp. DSM 109960|TrEMBL
MTTPLFSLEVFPPRRNAPVGTIYDTLDGLQGLDPAFISVTYGTGKSKDRTATARIANTIR
GEYGIPAVAHLTAQYLDKEAADEALDMFEAAKVEGVLALRGDSVEGETPAGVFEYASDLV
SYIREHRPQLKVYGACYPEKHPQARTLDEDIDNLKRKVDAGVTHLISQLFYSNDDFYRFL
DKARAAGIDVPIEAGIMPVTNAKSVRRMSTTCEARVPEPVETMLERWGDDSATLREAGIA
YASQQVADLVAHGVDGVHLYTMNHPAVTRRIWNNVSALFRN
>S6FQR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus velezensis UCMB5033|TrEMBL
MGLLQDLKERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIADLGADITGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVQGLSPVTDKEVKIRREEEVI
SVRNERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A1Q7ZJQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_20CM_2_68_7|TrEMBL
MNRPAPVFRLAEALRSGLPVVTCEIASGDGADAGDIVRRAHLVRDHVDAVNVPDNTAGIV
HLSPLAASALLVREGVDPVMHVTCRDRNRLALQSDLLGAATLGVRNVLCLTGDHMVHGDH
PDAKPVFDLDSLQLLVLANLLRGGRYMSGREIVPAPDLFPGATENPFAPPYDFRPLRLMK
KIEAGARFIQTQIXXXLDRRVPILAGVAPLRSARAARYLQERVPGMEVPDAIVRRMEQAG
PDRTRREDEGIRICVEIIEQLRDIKGLAGFHLMPIRWEEAVGEIASRARLLPARASLLGP
FAAAAVDDGGAEGCAAADGAALQHSREHRA
>A0A518XGV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea dispersa|TrEMBL
MSFFHANQREALNQSLAELNGRINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIARDYWNNGIRHIVALRGD
LPPGSGKPEMYGADLVALLKEVGDFDVSVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFAGLTNVRVPGWMNAMFA
GLDDDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAAAA
>A0A2D7A671|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetovibrio sp|TrEMBL
MPLTASNLADESIDESVRSFVNGFTAETTPFSAAKIDDFREVLRPGTTVFVTFLPGSDYT
DTLEVTKRLQDEGMRPVPHIAARSVPNKAFLEENLKILAEQSGIDEVLIIGGAVDQPVGD
FSDSMQIMETGLLDKYGIKKVGIAGHPEGSPDITQEAIRDALAWKNEFAERSGAELYIVT
QFCFEAEPIIAWDKAIQSEGNRLPIRIGLPGLATIKTLLNFAKACGVGQSMNFLKRQGKN
VAKLMTVSTPDKQMIDLARYKLEDPKCGITGVHMYPLGGVKKTAKWSYAVCDGHFDVTPK
GDGFKVNIDL
>A0A194W5N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Valsa mali|TrEMBL
MDKITDKIAALPPDANYFSLEFFPPKTQMGFANLRSRLERMARALKPTFVNVTWGAGGST
SQKSLELAETCQRELGLTTCLHLTCTNMSRRLIDKALEDAKVLGIRNILALRGDPPRRAE
YMDENDEDDLGDEDEFKWAVDLVRYIRQNHGDYFCIGVAAYPEGHADESHPLGQSMEHDL
PSLVEKVQAGADFIMTQLFFDIKAYDKFETTLRQHPSGAFKDIIIIPGLMPIQNYQMIKR
TTKLSHAGIPDDLMARLDEVKRDDERVKLVGVDILSELIEQIREIKSRTPGPQGFHFYTL
NLEKAVSFILERTHLIPPETPGGEQPLADDLVAVPTVEINGSLSNGSTLQHHLGVSDASR
RLSTHSSEPRNRVIISGERTPSNPEYEATQLEASRPYEPVHSRANTLAISEGEGVLGREA
TWDDFPNGRWGDARSPAYGEIDGYGVSLHMSVTQARSLWGDPSSVDDISTLFIRHLQGDL
RAIPWSEAEFNDETGTIKDQLVALNEKGWWTVASQPAVNGVKSTDPTFGWGPANGFVFQK
AFVEFFVPADQWRKLHEKLSKPEMKESIWFYAANAAGDFVSADSGSPLDQDVQEVGTNAV
TWGVFPGKEIVTPTIVEEVSFRAWAEEAFGIWGEWAQVYGKGSASTQFLEKMKGELWLVN
IIHHEFVEKDALWDLLLDA
>A0A416IW42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM54-14NS|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVFKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNVLCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A9KZI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella baltica (strain OS195)|TrEMBL
MAFHHAQHSQSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPGWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A5C8NW04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zeimonas arvi|TrEMBL
MTEIPSPAQAVDLSFEFFPPNTPEGARKLREVRARLAALAPSFFSVTYGAGGATRDKTMA
TVDEIAAEGRQVAPHLSCIGATRESVAELLDTWRARGIRRLVALRGDLPSGMVDTGDFRY
ASDLVAFIRARSGDAFHIEVAAYPEVHPQARSADDDLRAFVTKMKAGADSAITQYFYNAD
AYFRFRDDAQRAGVSAPIVPGIMPINNFVQLARFSDACGAEIPRWIRMRLAGYGDDLASI
RAFGLEVVCGLCSRLLEGGAPGLHLYTLNQADAAERIVQALRLRG
>A0A6N7XHH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptostreptococcus porci|TrEMBL
MSNVDKIRSSFPLLFDGAMGTYYIEKSEKPLPECEMANIFDRDKILDIHKEYLRAGAAAL
KTNTFGANRRSLRCTREILDTIIEQGYKIALEAVDNVKKENNDSSEKFIFADIGPVPYDS
SDDDSFSTLVEEYVAIVDKFLNLGAKNFIFETFDEGRALHEVSEYIKNKCDDSYIIVSFA
INPDGYTRKGYSGEKLLEDFALDKNVDSVGFNCISGPGYILRTVDKIKIPNKTISIMPNA
SYPTVVNNRIFYSDNANYFANTMLDFLDRGVEIIGGCCGTTPSHIEKLSNNLKKHRIQSL
KDEKPQVFKVRTKPSSNVFYDKLCGGKKVIAVELDPPADVDIEKYMNSLKRLKELDVDAV
TIADCPVGRARIDSSLMAYKIKNEVGLEPVVHLTCRDRNLNATKALLLGLNIENIRNLIV
VTGDPIPTAEKDEIKPVFNFNSRLLAKYIGELNENVFSNKMVISSGLNINAKNFLAELNK
ARKKVENGVEVFYTQPVLSENAIENIKIAKKELKAKIMGGIIPIVSHRNAVFMNEEISGI
NVDEKIIAAYENLTREEAAELAVSMSLEFIEQIEEYVDGLYLITPFNRVEIIRDIVNKYR
NKK
>A0A8I1T7S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp|TrEMBL
MPSISFEFFPPKTDDQRAQLDRAAQALKAHQPEYASVTFGAGGSTLSYTGDTVARLHTQH
GLNVAPHLSCMGGTRAEIAALLDGYRAAGYRRIVALRGDMPSGMATAGDFRYAAELVAFI
RRHCGDHFHIEVAAYPETHPQADDALRDLMHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VRKLGVNVPIVPGIMPISNYSQLRRFSEMCGAEIPRWIAKRMQAHGDDADAVRELGAEVV
AQLCRRLLDGGAPGLHFYTLNRARATQAVLQQLA
>A0A521VVK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthobacteraceae bacterium|TrEMBL
MQALRHWSVRHARGLARLYDVCARVAPRFAPLVSLIGAKRADRAIRPVERLAKQMFFDCK
MCGQCVLSSTGMSCPTNCAKEMRNGPCGGVRENGHCEVDPAMRCVWVEAVSGIKQIGGTL
PAQPASLLPIDRRLREQSTWARVIANDIVPVRAAPAPAPVAAHAPQAFEQVCRSGRFVVT
AEVAPPDSPDPAALLAQARLFEGQVDAINITDGAGGNCHMSSAAAAAILTASGFTPVCQV
ACRDRNRIAVQGDILGAAALGVRNFLCLTGDDVSQGDHPQAKPVFDLDAVSLLRIARTMR
EQGTFASGRKLDAAPNLFLGATANPFMPPYADRIANLQLKVEAGAQFIQTQFCFDVKMLA
DFMRAVRERGLHKHARIIVGVGTLSTAKALRWMAHHVPGVHVPEEVTRRIAAASSQRAEG
QKILIETMRALADIEGVGGVHLMGHRNGEVLAEAIAASGLRTAFAGTPSTIKLENQGACK
>A0A672U311|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strigops habroptila|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTRDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLNSQTQQ
>A0A257A257|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon ex4484_178|TrEMBL
MPWRQFIEYFLEGVEMIRLRDLLTEGKFTVTYEPDSPVGFKIDCEFPQKVVEKIDAFGVY
NNPRGIPKLDPFVYGWYLMNRYNKDVIVNIRTQDYTLPLFQSTLWGGYLLGIRNLLLVTG
DYHPGSPFLIDVTEGITGIRKYLNEGYRIPPLTGKAKKYYNRFLSGEFERKRAKGATDFF
VGAVLTPGRKGEKRIYKKKLEAGAQFFITQLVYDAEIIKKFLEDIEPEVPVLVGTAPIKT
MKRIKFLKKLGIQGLSDRIIKELKSSEDIGEKCVELCSNMYQELRDFAREYGIKTGAHIM
SIKNPVEAGKIIERIEK
>A0A2K9C4T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 02C 26|TrEMBL
MSLLKTALHEHAFVCIMEFVPKPSAERFAALEAIMARKQLCGWPLTVSIGDRVGSPLDMS
PLDAFNSLTTPVPALLHFSGKARERHDLLSQLQHMDAAGLDQLLILTGDRLPGHTPGQQP
VRYLESVAALQIARQARPDWLLGAALNPFKYREEEGAAQYLKAEKKLSAGADFLTLQLGY
DDQKHQEALQWMARQRTPKPLIACLMALTHGRAQMLEHVAGAVVTPSMRDVLAAELALSK
AYAQARSIQRLALQVVGLKLMGYAGVHLSGVHELAQLQTLERELEQVLASVHTLEQWAPA
WTASWQMPDLPTVTFTPPGANWRLDQSRVSASPRERVRYHLLSGMHGLLFDRENWASRAF
GWAVTRPLWSKPGAASLLHGLERGIKRPLVGCDTCGSCRLQDTLYICPESCPKGLANGPC
GGTSLNRCEFGDRECVHGVKYRVAKTVGETDVLRERLIPCVEVENRHRSSWPVWFQPAPV
VKVEPVVAVRRTAGSESVQREVAVAEVDN
>A0A369YK94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parainfluenzae|TrEMBL
MSYAKEINTLNQHLADINKKINVSFEFFPPKNEKMESMLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGLEAAPHLTGIDATPEELKEIAKDYWDSGIRHIVALRGDEP
KGYAKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDNYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMASFTNVKIPAWLAKAYEGL
DDDPTTRNLVAASVAMDMVKILSSEGVNDFHFYTLNRSELTYAICHTLGIRPTVNP
>A0A4Q0XLF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gelidibacter gilvus|TrEMBL
MKVTEHIAQANGNTQFSFEILPPLKGQDIKSIFDNIDPLMEFKPPFIDVTYHREEYIYKE
QENGLLKRQVVKKRPGTVGICAAIQNRYKVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VMALRGDAVKTETYFTPEKEGHEYANGLVQQIHALNDGVYLDEDLQNTSKTNFCIGVAAY
PEKHMESPSLDSDIHFLKKKIKSGAEYVVTQMFFDNQKYFEFVEKCRKEGITIPIIPGLK
PIATKRQLNLLPHRFHVDLPEPLILEVIKCKDNSEVKQVGIEWCIQQSKELQKAGIPVLH
YYSMGKSDNIQTIASEVF
>A0A1Y5LK80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. NCIMB 12038|TrEMBL
MTFDSVRGRASEGWVTRTPSIVDRIRSSGDGRVPFSVEFSPPRDEAAEARLWRAVREFER
MGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWEKHPQGVEYAEELVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLGSV
RRMLELSGSRLPAHLEKRLATAAGDGPEENRAAVREIGIDLATEMSERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSGVADPAPVTPAPVS
>X5PIN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSJC277A00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A5M7C1U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas chlororaphis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVNIPIVPGVMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A0B3BU16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter sp. YS13|TrEMBL
MLKNENLCTKLKKRKFVVTAEISTPKGVDITKTIEEARKLKGIVDALNITDCPMANMRMS
PIAVAHLLQDHLNIETIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDDPSHGDTPQ
AKGVYDVDSIGLLKIISAFNRGYDYNGNKLDSPTEFCAGTTANPSDLREEAIEKLKVKIE
AGAEFIQTQPVYDEDILFKFIEKIKNFNVPLLVGILPLKSFKMAVNLNEKVPGIDIPEKV
LERLKDGGREEGINIAVEFIKRIRSEVGGIHIMPLGSTDAVLEIISRVDDLACDFKENKV
QMN
>A0A7K0WTS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPRIADILNQATGPTLSVEFFPPKTPVGDANLQRTIEELRSVPLSFVSVTYGAGGSTRDR
TRDLVVGINENESYPAMAHLTCIGHTKPELEALLDDYDRAGVHNILALAGDPPADGSPAD
GDFTYALELVELVRARGDHFSVSVAAHPELHPRSTDSKDDRIHLAHKLAVADFGVTQFFF
SAPDYFAMVDELSALGCDTPILPGIMPLTNPEGVRRMAKMSGATVPEELAGKV
>A0A7V8Y8P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNDRPSIEAGSTGDAKASTSLFQADEGQVLADLLKRSALEIFPTPLIERRLDALAEGTQV
TITCSPARGIAETLALSEKLSSRGLRVIPHISARLVRDDAHLQEIVGRLASMQAAHLFVI
GGDVKKRAGKFPSTLSLLSAIADMDHPFVSIGVAGYPEGHPFLEDNSLVETLKAKEPLAT
YVVTQLCFDPGAIVGWIENIRGQGIGLPVHIGLPGVTQAHRLLRFALKIGVGNSARFLTK
HSNLVMQLAKSSYNPDDLLRDLAPRLGESAMRIEGFHLYTFNEVAATKAWRDQLVKDLEA
SKAIDVQRENSNHSTKGARHADSI
>A0A7V9CQP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MASRFLERLASGPPIVCDGGMGTLVSSAVARLRCPEEANLRAPESVVSVHVSFINAGADL
IETNSFGANRPKLAAHFLEDELRPINSAAVKLAREAREMASREVFIAGSIGPLGETPPGF
DAAAAFAEQAAVLEGRGVDLFMVETFFDLAELELAIDAVRGVSALPIVALLTFDEDGETP
GGATAREASGLAARLGLAAVGANHGAGPQSVLEALAGMEGCGLPLAALPNLGLASRWGNR
IVFPHADPEYFGEFAAHARDLGALLVGGCCGTTPLQIQAIRDALEADRPTTTPIFVSERL
LPAAGAPRPEETRLARTLAEGQWTTSVEINPPKGGTSDGMLELSRQLAASPNVGFVDIND
NPTARARMSALMAAVAIEGACDLETIPHLTPRDSTIMGLESMLLGAHAAGVRNVLSVTGD
PPDIGDYPGSQGVYEVDSIGLCRIMQRLNEGESYAGKTIDAPTSYFYGVAVNPSADDLDL
ELRRFEEKLEAGASFAITQVLFDLEYAERFRKRLGGSWPVPVLLGVFYVTNYALALRLHN
EVPGIVVPDPVQERFRNAGAAGREVGLEIARELVAGSRELFDGVQVIPPFQAPL
>A0A7V9C0X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSTRFLERLRSGPPLVADGGMGTLLSGAVPRLRCPEEANLRAPESVVALHASFIRAGADL
IETNTFGANRRKLATRFLEDELEQINSTGVRLAREAREMCGGEVFIAGAIGPLGELEQFD
AGESAALFVEQARILEGRGVDLLLLETFYDLDELVAAIEAVRSVSQLPVVALMTFDAEGQ
TLGGVDAGAAAERLDGLDLAAVGANHSAGPAAALNAIARMQADGRILAALPNVGLASLAG
SRVIFPHATPEYFAEFAAQARRLGAGLIGGCCGTTPAQIAAIRAAVDEDRAPSAPYVVRE
RELLAASETVVEETTLARMLREREFVISVQLDPPLGGSNVTLLETARVLRESGKAHLVDV
NDNPRARARMSGVMASVAIERACGIETIPHLTPRDMTVAGLESLLLGTHAEGVRNILAVT
GDPPEEGDYPGARGVYEVEAIGLTRLIANLNRGEDNHGRTIDAPTSFFTGVAVNPSADDL
EVELDRFERKLEAGAQFAMTQVLFDLRYLDAFLAHFGGRSPIPMLVGIWPLRSHQLAVRV
HNEVPGMVVPEAVQQRLLDAGSAAAAAGAELARELIVESREKAAGVYLVAPFRQPLGILE
IL
>A0A7K0UKW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSADTAPTISFEFFPPKDTVAEENLWNAIADLQQYQPDFVSITYGAGGGTRDRTVRIASD
FIARTGVPVIGHLTCVGSTRNELKEVLEQYKSEGFHGVLALRGDPVGGPTAPWVTTPGGF
DFADQLVALAADVGGFSIGVAAFPDVHPASDGNFVQDVNVLLRKEELGATFAITQFVFDS
GRYEALRNALDQRGSKLSIYPGIMPVTSYPQIVKMLELSGGYMPKATRLRFARYQNDAVS
LKKLGIDVAVQICEDVFALGAEGLHFYTLNNAGPTGEIIKQLSMLSR
>A0A7W1N236|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MADRFTTRLREGPPIVADGGMGSLITAAVPRLRSPEEANLRAPEAVVSLHVSFINAGADL
IETNTFGANRRKLAGRFMEDDFERINSTAVKLAREAREVAGRDVFIAGAIGPIGEPATTR
VRHDLFAEQAGVLEGRGADLFMVETFFDLEELVDAIEAVRSVSSLPIVALMTFDEGAETL
AGVSAREAAERLRGLDVAAIGANHGSGLLTALEALEQMGGDLPLAALPNIGLASLSGGRV
IYPHAAPEYFAEFAAHATQLGARVIGGCCGTTPVEIAAIKAAVEAQRKPRAPLEFSEREL
VVALGEEQRETGFARALREGEFVVSVELDPPLGGSAAGLLEVASQLHDGGIRFVDVNDNA
TARAGMSSLMVSARIERDTGLETVPHLTTRDSTVLGLESILLGAHAEGVRNVLAITGDPP
EVGDYPGSRGVYEIDAIGLTQLITRMNRGEDYHGRPIDAPTSFYVGVAVNPTADDLEEEA
ARFRRKVEAGAKYAMTQILFDLDVLDRFAEVLGGEWPIPVLAGIFPLTSHRLALRLHNEV
PGIIVPQPLQDALAGAGSGAAVLGFAHAKELLIEARERCSGVYVVPPYKRPARVLELLA
>A0A6I2KYS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella guangzhouensis|TrEMBL
MDNPNFSIEFFPPKTAEGAEKLRVTRAKLSELKPKYFSVTFGAGGTTQQGTLDTVVEILA
AGEDAAPHLSCVGGTRDSIRQILADFKSHNIKRIVALRGDLPSGYGAAGEFRYANELVAF
IRQETGDHFHIEVAAYPEVHPQAKSPQDDLLAFERKVKAGANAAITQYFYNADAYFQFVE
QTRKLGIDVPIVPGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTGLAERLLQGGAPGLHFYSMNQAAATTALWQRLV
>A0A7K0VHJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVVTSTTVQGISPRAPGAVATMSIFRSRQRSGTVDEQPIAQGILDRVAHAHLELIPTPKA
HLQFPELPEASTVSVTCSPAKDIQATLDMAAQLQDLGHTVIPHLAARMVEGPEQVAAIAQ
WLNAHDVRDVFVIGGDAPDPHGPYLDAGALIEALLNSNANLANVGFGGYPEGHATIPLNK
LADAVASKQQLLDTAGVGGWVSTQMCFDTKAVSKWIQHSRSQGLHLPIHLGIPGVIDTTK
LLTMGAKLGIGASLRYLRKNRAVVSKLAAPGGYDPMEMLSPLAREFESLDISALHVFTFN
QVANTAAWRRAVIGVAAHAH
>A0A7V1YJK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVSPPGEEHRVRHAAHRVHGARDRARGRHPEERAGAGGGGPDAALGPEEGDPQAVSQAAP
SGTVGRLLANARFEIVPTDGLEAELRHLAPGTTVTVTCSPRKGIDRTLEIAEHVQGRGFR
AVPHLSARLVTGRSHLRAILRRASDAGFRELFVVGGDATEPAGPYASAGELLREMAELDH
GVEAVGVAAYPERHPLIDEEELLRALLEKQPFAHHMVTQICFDPGALVRWLDEVRGRGVT
LPVYVGVAGAVRRRRLLEISLRVGIGDSVRYLTKHGGIVARLLRGGSYRPDGFLAGLAPL
VAGREDVLGLHLNTFNQVEATERWRREALRAYGYAPAAEAFPEEDAAS
>A0A7V1CK03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAKKTYSGSNLEKILKAGKFAVTGELGPPKGADANVVLDKAALLKGEVDAVNITDCQTAI
VRMSSIAASQLVKSRGVEPVVQMTCRDRNRIGIQSDLLGAWALGMKNLLCLTGDHQKFGN
HPESKNVFDMDSIQLVQAVRDMRDKKQFINGEEIERPPSFFIGAVENPFAEPFEYRAPRL
MKKIEAGADFFQTQIVYNVEKFKKWMADVRKLGGHKKAYILAGVAPLKSAGMAKYMKKFV
PGMDVPDELIKRMEKAKDAKEEGINICVEIIKEMKKIDGISGVHIMAIEWEEAVPTIVER
ADLSPRPKVN
>A0A7K0QQK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDDILRQGPDPVFSFEFFPPRTPEGEANLYEAIAKLAPMDPAYVSVTYGAGGSTAGKT
LEIASTIRERHGIEAMAHFTCVGATVDELRATLDEMRELGFENVLALRGDPPAGQDEWVR
TDGGFEYSRELVELINADYAMTVGAAAFPETHIHATSPEDDLRHLKAKVDAGVDFLITQL
FFDNAVYFDFVERARAIGIDVPIIPGILPITNIAQLDRITSLCGSEVPARLRAELDLRTD
EPEAVEDFGVAYATLQCAELLAGGAPGIHFYTLNRSPATRAIVGALRLQRPWDTAGA
>A0A7V9T8U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSRFLDRLQSGSPIVADGGTGILVSSAVSRLRCPEDANLRAPESVLALHLGFIRAGAELI
ETNSFGANRRKLRGLFLEDEVKRINEAAVKIAREAREVSGRDVFIAGAIGPLGDTGGSEE
EGGAVFAEQAELLEGRGVDLFTVETFYDLEELLVAIAAVRSVSSLPIVALLTFDDDARTL
AGVTAEEAAAQLSQQDVAAVGANHGGGPQAALRAIEQMGADGLPLVAMPNVGLASLAGQR
IVFPHATPEYFAEFAAHAQELGARIIGGCCGTTPTEIAAIRRAVDERRRPTAPLVVRERE
LLVPSTPSQADTLLARKLGAGEFVVSVEIDPPRGANPDGMFEIAQTLQDSGHVDVVDVND
NPRARARMSGMMASVAIERNVGIETIPHLTPRDSSVAGLESMLLGAHAEGIRNVLAVTGD
PPDAGDYPGASGVYEVDSIGLSKVITQMNRGEDFNGAEIDAPTSFFLGVAVNPAADDLGY
ELDRFEQKLEAGASFAMTQVLFDFEFLDSFLERLGRECPIPLLIGIFYVRSYQLALRLHN
EVPGIVVPERVLARLQDAGPEAGAVGLELAKELLETSRERAAGVYLIPPFRQPLAALDVL
G
>A0A0U3SXN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermococcus sp. 2319x1|TrEMBL
MTTCPKDLLNGPCGGVLNEECEVDGRECPWVRVLEKFKMNPANLFEEHPLLLELEDLVNG
DSIPRASVFWQNLEKGKALSVEFPVAAVSKPHESLRVFRGISADLITVPDNPLGYPHYDP
VAVACYLKSLELRSGVMPHITAKDRNLNALTSELRTAQVFGCEAVLLTTGDWPSFAVPSR
PVFDVDASNLIRLARLVFAGVMPTKEVLKVEDRPRVASVMNPHYRPKIEAKRLARKLIAG
SEAFFTQVVAARESATGISKIIEELKKYAEVDVPIIASVLYPMKEEIKPFLRALGIPVGD
EPFEVLLEELKAVEAVRGLNLIVSSRSLEEWLGLWREAREIIEGVFE
>A0A7K0Q2Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTQSAAGANLAQLLATGGRSFSFELFPPKTDEGEQALWRTVRDLERLNPTFVSVTYGAGG
STRDRTVRITAEIAEQTSMIPVAHLTCVGASREELRGVIGEYAAAGIHTILALRGDPPGG
PTAKWTPHEDGLQHADELVELIKALGNFTVGVAAFPEGHPSSPDLDTDARVLAAKQDAGA
QFAVTQFFFRSRDYADLLERATAHGVTMPIIPGLMPVTNVAQIARFADLSGAAFPPELAA
RFELVKDDDDAVRKLGVEIAVEMSNELLAMGAPGLHFYTLNRSTSTVQVYEALGLGSR
>A0A7K0LJ72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKIADALKAGPCYSFEFFPPRSEEAERNLATAIRELAPLAPAYVSVTYGAGGSTRDRTHD
LVVEILRDTGITPMAHLTCACHSRQELVDVVTRYRDAGIENILALGGDPPADSDQPPGEL
KYASELVDLIRGVGDFSIGVAAHPEPHPHSPSIEEDRRRTAEKLSKADFAVTQFFFDARH
YFDLVESLHELGVDKPVIAGIMPATSMRSITRMSELQGSEFPKDLAAKLEAAEPDGPEAV
HRVGVE
>A0A7U1KTT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Reading|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7K0Y3J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVVGTSYSFEFFPPKDIEGEGRLWHAIEGLKSIAPDFVSVTYGAGGSTRDRSIRIAREIT
NRTGIPTVAHITCVGSTRNELLEILNSYKDAKITSILALRGDPTGGPLAPWLPTENGFNH
ADELVELAKECGGFKIGVAAFPDGHPSSGGDFEKDIDVLIRKEKLGATFATTQFFFDVKA
YKNLVERLAKRGSALTIIPGILPVTNVKLLHRMAELGGTPIPDHIAKAFAEVESDSQAVR
ELGVEIATKLCKELLEAGAPGLHFYTMNSSTATVEIYRRINNVN
>A0A6I2X184|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MEMRMAKVGEAVTYSFEFFPPKDQEGEDRLWSAIAALEPIKPDFISVTYGAGGSTRDRTI
RITSEITEHTKLPVVAHLTCVGSTRDELLEILARYKDAGIHNILALRGDPTGGPRAPWSP
TPGGLNHADELVSLAADFGGFTIGVAAFPDGHPASNGDFAVDIDTLIRKEAAGATFATTQ
FFFEVDKWKSLVDKLAARGSQLPIIAGILPVTNVNQLNRMSELSGTPIPGAMSDAFEKIK
DKPDDVRKLGVDLATKLCEDLLAAGVPGLHFYTMNTSTATREIFALIKDKKRA
>A0A3S9F4C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M8A.F.Ca.ET.057.01.1.1|TrEMBL
MTGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHDEITETQVDMVK
TAH
>A0A2I1KSI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces urogenitalis|TrEMBL
MENTMSPSLAQPYTRHVAPKPSPAAIAPSLTPAEPARPSLSLELFPPRPGRYASQTWGAL
DRLLAARPDFVSVTYRPRFITTAGGPTAAAGSPTRLHVVREHNPSEDVVAHVIATSRVPL
MAHLTCLGYRKANVVEIVRLFLDMGVRRFLALRGDPPRGVAAEDVVGELRHADQLVRVIR
EVEAEYFDDGARHVQVAVAAYPAAVDYAREIGVLAAKQAAGADLAITQVFYESEDYLALA
RAASYCGVTMPILPGIIPLTDLRRLTRLEDLTGVSVPTRLSQTLTSRQGASVMTAGIDAT
LQLAGDLIEGGAPGLHLYTFNRTRPALDVISQFRLGGVLDGARPDRVTQREIARAYINAV
PGSGARLTGRMPVAARP
>A0A538K0F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MCRASSEGDVVPAQAQTRNRFQERLETGPAIVGDGGMGALLSAAVPRLRSPEEANLRAPD
AVVSLHVSFINAGADLIETNTFGANRRKLSHHFLEDDLEQINSAGVKLARDAREVTGRDV
FIGGSIGPLGEPATSRVRRELFAEQAAVLDGRGVDVFMVETFYDLEEVVDAIEAVRSVSS
LPIVALLTFDESAETLAGVTAAEAAARLTDLDVAAIGANHGAGLLAALAALEQMGKDGKP
LAALPNVGLASLTGGRVIYPHATPEYFAEFAAHARDLGAKVIGGCCGTTPAEISAIRAAV
EDERKPRAPLVFDAPELVVALGEEQRETGLSRALASGEWVVSVQLDPPLGGNSAGLVEVA
TALKESGHVGWVDVNDNATARAGMSSLMVSATIERLAQIESIPHLTTRDWSVMGLESMLL
GAHAEGVRNVLAITGDPPEVGDYPGARGVYEIDAIGLTQLMTNLNRGEDFNGRPIDAPTS
FFPGVAVNPTPDDLDVELERFQQKLEAGARFAMTQIVFDPEYLDRFVDRLGGAWPIPVLV
GVFPLTSHRLALRLHNEVPGIVVPQSLQDALERAGSDAAEIGFAHAKDVIAASRDRAAGV
YLVAPFRRPLRVLELL
>R9I8F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola sartorii|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYDTIDTLREFDPLYINITTHRSEYVYREL
GDGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEENGYAHALELEEQINAFNEGKFIDGTPIQAPLSPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVETGASYVVTQMFYDNQKYIDFVERARKEGIHVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVMEAMKCKDNKEARALGIEWCVNQCRELIEYGVPGIHF
YTVGAVENVKEVARAVY
>E9DNB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. C150|TrEMBL
MLLSQQKSKKKKVKYMTSQTPSLSFEVFPPNPAVGNEKILLALEDMKGLSPHFISVTASN
NKYNIKETTVPLANHIQNDLAIPTIAHLPAIYLTKEKVADTLRELDAVGVHRILALRGDI
IPGVEPLKDFTYATDLIEFIKEKAPQFDIVGACYPEGHPDSPNQISDIQNLKKKVDSGCS
SLVTQLFFDNERFYDFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRA
ILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNAATARHIYNATHALFKSH
SNSEK
>A0A166X4N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas luteoviolacea DSM 6061|TrEMBL
MALSLQEKILDPNQGVYLIGTTPPKLGTDKEQVQTIASKLLNRLHEIEYDGVVIYDIQDE
SSRTEIPRPFPFKQTVDPCEYSQVVSQLSKLDVITYKSVAQRDRGEFTQWLHKTKQDFGL
NNLVLVGSPSSKGDIKLGLPEAYQTLETHQDEFFLGGVTIAERHASKRNEHERLIDKTAQ
GCEFFISQAVYDAQATIDLLTSYARTCRQQGIEPKRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDAENTLKESIKICRENLDLILRSCAQLDVPLGLNIESLTNRKEEIDASISL
YRLLKAIMELQLAEKQIA
>A0A538BS02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSWRFWKRRRASGLTEEHRAALKSLVADARYELIPLSSALESASALPPGSQVTVTASPSH
GIEATFDLAEAVAAQGHDVTPHLSAHMLRDRAHLADLLERAQANGLRKVFVVGGDTRDRG
ELHDGLMLLRAMDELGHPFEEVGVPCYPEGHPDISDERLLEVLREKQRYANAMTSQMSFN
PAAVTRWVGEVRDAGISLPLHLGVPGVADLPKLMRIAARIGVADSARYLKKNKQLLGHLV
RGGSFGPDEFLEQLAPMLADPVADVRVLHVFTFNQVEQTAAWQRGMLDELSA
>R4NXT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)|TrEMBL
MRKSLEIGKCVVLEVLTPRGTNLGRFMEFTEEAWKTGIDAFTVTDMPMGRVRMAPWAASH
LLVESGKDVLMHFTRNTRNMIRIQSDLLGCHALGVKNLLLLSGDNPSHGDYPETTSVNDI
DILDLIRLTKLMNEGTDLAGNKIYGKTDFFVGGALNPFSDKDIKRAKQKIEAGVDFLVTQ
PLFNSEVAKKIKEELNTKILASIVFFENAKQMSYFSSVPGIEIPDEIVNSTEKGDDYLKE
KSFESVLRFVEETKGVLDGFYIVAIVKDLEKIRKVVEIAKS
>Q2UEQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus oryzae (strain ATCC 42149 / RIB 40)|TrEMBL
MHIKEKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAAEGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLLPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIKDLSRLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLIE
LNNRGILTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDSWYLVNIVNNDFHNTYDLFELFKDLNVRDFDVEVAADNADLK
SQENETAETTAN
>A0A4P7R9V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp. PAMC20947|TrEMBL
MGLPISIEFFPPKTPEGAEKLRAVRQQLYGLKPQFCSVTYGAGGSTQQGTFDTVGEILTE
GMDAASHFSCIGATKASVRAELATLKAMGVKRLVALRGDLPSGYGLGGEFHYASDLVAFI
REETGSDFHIEVAAYPEIHPQAKSPEADLQAYVSKVKAGADAAMTQYFYNSDAYFRFVEE
AAKRGATVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
SDLCEQLRKGGAGALHFYSMNQSVATLAIAKRLEQT
>A0A538LNH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSRLEDAIEAARFVVTAELLTVDAGGLDAVHERFAPFADYVDATNATDNTSAHAHASPLA
VAIALQQLGMEPVMQLTCRDRNRLGLEAEIAGAALHGIENICCLTGDDVTAGDEPEARRV
FDLDSVQLLVAAGQMAAGHYLSGRKIDPPPKLFLGAVENAGAPPYDYRVDRALKKVRAGA
RFLQLQVGFRPEQTEAFMREAVDKGLATQCALIPSICLVRSPGALRFIDEHVPGIEVPAE
IIARCERAADPEAECFEVACELAERARSLPGVAGLHLISFRKEAGIARLCQRLGIPTRET
RANSRPVAV
>F7GJ76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macaca mulatta|TrEMBL
MVNEARGNDSLNPCLEGSASSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDLCVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYE
EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDALELLNRPTQNEREMEAP
>A0A8C7N0E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus kisutch|TrEMBL
MPASFAPSTSVWDLGLVRDNRCLSGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRR
TESGDHWFSLEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMI
ASTAVNYCGLESILHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGF
NYATDLVKHIRCEFDDYFDICVAGYPTGHPEADSYDEDLRHLKEKVDAGADFIITQLFFR
ADTFLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDA
AIRNYGIEQTVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVS
AHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKS
SKDALLKMWGEELTSEQSVYKVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMMDELD
KVNRRGVLTINSQPTINGKPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKY
EPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWI
EQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPDEQPT
EQPVEQPAEESPVEDQSPK
>A0A6S6TCR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Sulfurovum sp|TrEMBL
MFEKFCKKLCSDETFISVEITPPHGASIKPTIEKIKALNLHEKVAGFSVTDNPLAKLKMS
GVLSAIQVQQAFEKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKYSDQPE
VKGVLERDSTLLLSIIYRLNNGLSYSNKELNPKPNPIYPFAVSNAHAKDMRRIKKGMLKK
LNYGARGIITQPVYNLENAKELLEIFQECREESVRDTAKDAQLILGQFPVVRAKTANFIS
DKVPGITVPKGIIEEMDLAAMDGIEKEQEVGFNISKEIFDDILKIHPKMHLMTHNRFDLC
SKLIGDN
>A0A8C7HUE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus kisutch|TrEMBL
MVNQVQRVEDTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIR
NYGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVN
RRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPADKN
QAMRSKELSVEL
>A0A7L1YXL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scytalopus superciliaris|TrEMBL
MVNETQQSCSASSSSRSEGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYETDLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYITGEPNRNGYRVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7I7YXV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium parmense|TrEMBL
MEFGPCGGVRPDGQCEMRPGACVFGDVVPWSGDRAAQRPVRAPLVLADFSCTPFDRHDVA
ATATVLASGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDRNRVVLEQELRG
LQTVGVDTVLCVTGDGRGYDVRPDVTQTFDLDGPRLISLAASIGVTPAAPETPTAPPVHA
RPARLVEKQRAGAGLAVLNHVPFPGMIADFMKSARSQGLSLPVIAAVAVFTDGVSAAVLQ
GLPGLELDPAVTEEVLGAADPVAAGIAAAVAEARALLSIDGVEGVNVSGLASASGAHIGA
EIKAEVGRRIRAETEAR
>A0A8C7HU29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus kisutch|TrEMBL
MFSPVCDGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTESGDHWFSLEFFPPRT
ASGAVNLISRYVAEALACSSNSALSFELENYHLFDRMGSGGPLFIDVTWHPAGDPGSDKE
TSSMMIASTAVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWE
EEEAGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFII
TQLFFRADTFLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMQVIEP
IKDNDAAIRNYGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRT
LPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLF
YLKSKSSKDALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNL
LKDELDKVNRRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALL
KVLKKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDE
AFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNP
PEEQPAEQTAEQPNDEQSDKEQPGK
>A0A6P8B8C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnaporthe grisea|TrEMBL
MHIRDMLAETEKTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVTQAQTYFGLETCMHLTCTDMGVEKVNDALDKAYKAGCTNILALRGDPPRDKEK
WEAAQDGFHYAKDLVSHIRKTYGDHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGRVRERGITVPIIPGIMPIATYASFLRRANHMQARIPEEWMQRL
EPIKADDAAVRVVGRQLVVELCRKILAAGIHHLHFYTMNLAQSTALILEDLDWLPSPNKP
LKHALPWKQSLGLRRREEDVRPIFWRNRNKSYVMRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLLGTNEQNRKKYGEPKSVKDIATLFVRYVQKEVDTLPWSESPLDAEAELIRDDLID
INLRGLLTINSQPAVDGVKSTHPIHGWGPPNGYVYQKAYLELLVHPAIFEQLKERIHNHP
DLTYYAVTKSGNLHTNASYEGPNAVTWGVFPGKEIVQPTVVENISFLAWKDEAFQLGMEW
ARCHDQNTPSRILLQSIMEEWYLVNIVNNDFHAPRTIFETLKDLTVPDIDKEIVSSALPI
AAPEAAAVNGERNGAQSNGITAAVTAS
>A0A6S6SI32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Sulfurovum sp|TrEMBL
MFEKFCKKLCSDETFISVEITPPHGASIKPTIEKIKALNLHEKVAGFSVTDNPLAKLKMS
GVLSAIQVQQAFGKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKYSDQPE
VKGVLERDSTLLLSIIYRLNNGLSYSNKELNPKPKPIYPFAVSNAHAKDMRRIKKGMLKK
LNYGARGIITQPVYNLENAKELIEIFEECKEESVRDTAKDAQLILGQFPVVRAKTANFIS
DKVPGITVPKIILEEMDLAAMDGLNKEQEVGFNISKEIFDDILKIHPKMHLMTHNRFDLC
SKLIGDS
>A0A1V6B848|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin141|TrEMBL
MKVTEHLRQSKKTLFSIEVLPPLKGKSIKSIFNAIDPLMEFKPPFVDVTYHREEFVYKKR
EGGYLEKISIRKRPGTVGICAAIMNHYKVDAVPHIICGGFSKEETENALIDLNFLGIDNV
LLLRGDSEKHEQHFSPEPGGHSYAIDLVNQVVNMNSGVFLDDDLKGVEPTSFCIGVAGYP
EKHFEAPNLNTDISNLKKKVDAGAEYIVTQMFFDNEKFFSFVKKCRDAGITVPIIPGLKP
LSTRKQLTILPKTFHIDIPEALYKEVEKCADDAAVKSLGVEWAVQQSKELIKFGIPCLHF
YTMGNPENIRLIASQTF
>A0A3R9U7D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
KVQAGANAGITQFFFNPDSYFYFIERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEI
PRWIRKQLQAYGDDSESIKAFGHEVVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLG
LN
>A0A0D7W8D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tamlana sedimentorum|TrEMBL
MKVTEHIKKANGKTLFSFEIVTPVKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVE
KNGLLDRKTVRKRPGTLGISVSLKHKYNIDPVPHILCGGFTKEETEYMLVDCHYLEIDNV
VALRGDAMKHQKYFEPTKGGHTYACELVQQITDLNNGKFLHEENLTQFKTDFCIGVAGYP
EKHMEAPSLQTDLKRLKAKVDAGADYVVTQMFFDNQKYFDFVEMAKSAGINIPIIPGIKP
LAVNRHLQLLPHVFSIDLPEELINAVDACKDNKAVRQVGIEWAIKQSKELKAAGVPVLHY
YSMGKSDNVQAIAEALF
>A0A380UQV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEVSKSYPESIDKVLHFSGKAR
DIQDFERFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGFR
IGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQQI
LACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKHLG
FAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVKTGKEFTPEIARFSRQP
TSKQIIKYRQLHVMHEAMFGSKIAKGVGRFIFKAPFWENSVVAKALLKTEVLSKHSLVGC
ESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKKTEI
LKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A1M7NM26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas asturiensis|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKADLRALLSQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFY
FVERVQKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITEMCERLLQGGAPGLHFYTLNQADPSLAVWNNLKLPR
>A0A522TRE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Castellaniella sp|TrEMBL
MNPAQTVSLEYYPPRDIAAQERLVRSAKRLSALNPAYVSVTFGAGGSTRAGTVDTVQMLQ
NLGSEVAPHLSCMGASRADLQAILDDYQARGIRRLVALRGDMPSGMGGDTGDLHHASELV
AFVRERYGDQFHIEVAAYPEMHPQAQSSEHDLQHFVDKVRAGADGAITQYFYNPDAYFHF
VDRVRARGLDIPVTPGIMPITNYTQLARFSEMCGAEIPRWMRLRLQGFGDDKASIRAFGV
DVVTQLVAQLLEQDAPGVHFYTLNHADAVAQICANLGVR
>F1MF22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos taurus|TrEMBL
MVNEPRGNGSPGPRWEGSSSGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKH
IRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDEFPNGRGESGGPHVGCLEGAYRGRDRSDCCSSWAHPSQV
TCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGWGPSGGYVFQK
AYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREII
QPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDN
CLWQVVEDTFELLSRPPQDKRETEAL
>A0A1R0YF30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus borealis|TrEMBL
MKPDLRSAWNTNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPGVIEDVHRSYIEAGAVL
LESNTFSANYDRLSKYGLESKVGEINRAGVRIARQAAGEAGYVVGAVGSIRAGKRANLSS
SELKRYFTEQITALLEEQPDGIMLETFYDVEELHLALRTVRKLSGLPVICQLAVDETART
LDGLTLPEAFRILEQDGADVIGFNCRTGPNGIKRALKTLQGSLTLPASVYPNAGVADYVD
GQYRYGATPDYFGQMAPVFAGLGSRIIGGCCGTTPQHIAEISAALRDYAPQPLPEPTQKK
SPERIVVQEHLGEDEDRSGGEPTLVDLVKERHTVIVELDPPRDLDIAKFMRGADALRRAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHVACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIAHIAKATEHLDIPIFLGIMPLASGR
NAEYLHNEVPGIQLSAEVRSRMQGLEGEVGRAEGVAIAKELLDAATEHFNGIYLMTPFMF
YEMSVQLLEYIWEKQGRKLSPLFR
>A0A354DJZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillaceae bacterium|TrEMBL
VQVARGAVGEDAYIIGDIGSINAGRVRERNMKGFKEQFEEQASSLLYAGVDALLLETFLD
VEELLLALEVIRPMTTKTIVAQLATIEVGLTRDGYSLTHAFEELKKAGADVVGLNCRMGP
AEILRSLEKTIVPTDLPLSVFPNAGRLGLSDGEYNYKSAPVYFAESALRFRDQGVRLIGG
CCGTTPEHIKAMADALKDLKPVSRVNPVVDEIVEPVVHVTQPERVKKPEGIVDMVAKKPT
IIVEFDPPKDLEVESFIQGCSMLEDAGADAVTLADNSLANTRMSNMALGAIMKNRLGVEP
LLHIACRDRNLIGQQSHLMGLHALGINQVLVITGDPARFGDLPGSSSVFDVSSFDLIRMV
KQLNQGITFSGKPMKQQANFVVGAAFNPHVRHFDAAIKRLEKKVEAGADFIMTQPIYDAE
MLKLIYDRTRHISIPIFVGIMPLTSTRNAEFLHNEVPGIKISESARERMRKHGVGPEARQ
EGNAIAKELLDVAMQYFNGIYLITPFSYYEMTAELTRYIREKQK
>A0A396LAP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. OF03-6AC|TrEMBL
MKDVREILKKRPLLFDGGMGTYYKAKPGQECEQANLLDPDGVLTVHRAYLEAGADAIKTN
TFGLPRMAAAQNPMWEAMADEGWKLAAQAAVKTSAAVFADLGPAPDTEALPAAQIYTALA
ERFAALGAKNFLFETLSSDAGVAEAAKKIKETVPDAFVLVSFAVLPDGYTREGRHCAELV
RSMTACGAVDAVGLNCVSAPGAMRTLVQQLGRTELPLSVMPNAGYPVVTRTRVQYQGRPE
YFARELVGLAAEGVRILGGCCGTTPAHIAALRAALDALPETLPAAPAAAVSTAAKPEVET
DDAFLRKLNAGKKVIAIELDSPKDADLTGYLDGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGLNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPLTVFGALNLNARNFDVELRRAQEKLQNGMSGFL
TQPVLSAQAVVNLKKTRETLGEKAKILAGIMPVVSQRNAIFMENEVNGIHVDAEIIERFA
GLDRAQGEELGLEVSVKAAQAAAPYADGFYLMTPFNRIALMERLIARLKDEGIAD
>A0A2H5VKJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR08|TrEMBL
MALLGILRAKAEAGERTFTVEISPPVNYKTIVKTSEMVHALRDFDIAGIAVTNSTGGSFR
MNPLAVVEAIRAWRPETPIVIHLTARDEGSVRSVYSRADEMNRRAVSDVLVLRGDPTPHR
SREVDAFKFSTVELVQLIREYRDEQGYAIDIFVAGHPEYPSHALAKHMAYQRRKIEAGAQ
GIIANIITDPANYARYAEAALAHGIAVPILPSVIPLTSARRCLFLHTSLHIPVPREIVER
LERARNKEEAARIGLEITIEIVERLLSDGAPGVNFNLIFPQDIASVADILRAVRGHATIW
EKYKIEDPEEIEYYSQLRGRLS
>A0A6M6IE26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diaphorobacter sp. JS3050|TrEMBL
MSLSTAFPVSFEFFPPKTPEGADKLRAVRQQLYARRPEFCSVTYGAGGSTQAGTFGTVRE
ILAEGVSAASHFSCIGATKDGVRAQLAELKAMGVKRLVALRGDLPSGYGIGGEFHYASDL
VAFIRAETGRDFHIEVAAYPEVHPQARSSDADLQAFATKVRAGADSAITQYFFNADAYLR
FVQDVRRLGLDVPVVPGIMPIMGASQLLRFSDACGAEIPRWIRLRLQGYGDDVASIRAFG
LDVVTHLCEQLRREGVPGLHFYTMNQSAATLEICDRLGL
>Q12RJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)|TrEMBL
MAFHHAQHAQSLNQSLSEVNGAINVSFEFFPPSTPEMEQLLWSSVRRLEPLKPKFVSVTY
GANSGVRDRTHSVIERIQQETQLVAAPHLTLVDASDEELVDLAKQYWQSGIRDIVALRGD
LPAGQPKPTRFAADLVRLLRSVADFDISVAAYPEGHPDARNAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVTNFTQLKRFAAMTNVALPQWLHQQFS
GLEDDPATRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPKVAV
>A0A7Y3W5D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvularcula mediterranea|TrEMBL
MAASSARSGASTNLFPPFTALPRRRRPLSDLSVSFEFFPPKTEKMAETLWASVDKLAPLG
PSFVSVTYGAGGSTRERTHDTVERIVRDTDIPVAAHLTTVSATKAEVDSVLKRYWDSGVK
HIVALRGDPPEGVGEKYVPNPEGYAGAAELCEGASAIAPFEITVGCYPEKHPESPSLAYD
IDLLKRKIDNGATRAITQFFYENDVYERYVERVRAAGIDIPIVPGIMPVTNFKALKRMSK
LCQATVPKRYAKLFDHLDDDPKTRQLVAATVAAEQCHDLADRGVDHFHFYTLNRSELAYA
LCHMLGVRPAETAEAA
>A0A383SSI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. juglandis|TrEMBL
MTPLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSFGDDAEAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1G7BJM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus tukisamuensis|TrEMBL
MDRIGSVSGRIPFSVEFSPPRDADAEARLWRAVRTFEGLGPAFVSMTYGAGGSTRDRTVR
ITGDLAEQTTLLPVAHLTAVGHSVDELRAMVGAYADRGISNILVLRGDPPGDPLGEWHKH
PDGVEYAEELVRLVRDLGDFHVGVASFPEGHHRAPDLDHDTRYLVSKLRAGAEYSITQMF
FDVDDYLRLRDRVARLDPEQGAKPIIPEIMPITSLRSVKRMVELSGSRLPRSLEERLDRA
AGNGPEEDRAAVREIGISVATELGERLIAEGAPCLHFITLNFARATREVLTRLGLASAPA
ESPVASAGAR
>A0A2T3IWZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium lutimaris|TrEMBL
MGYSHASNLDSLNQNIADIDGNINVSFEFFPPSSEQMEQTLWNSIHRLKTLQPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLVAAPHLTCIDATRDELRTIARDYWNNGIRDIVALRGD
LPEQGTKPDMYAADLVELLRSEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNMNQAKRFANANNVRIPGWLEKQYE
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAKA
>R5FLX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. CAG:924|TrEMBL
MKVIDILRQQTGQRRFSFEVLPPLKGNGTEALFRTIDKLKGMDPIFINITTHHSEYVYRE
TDNGQYERLRIRRRPGTIAIAAAIQQRYGIPVIPHLICSGATAEDIEYELIDLQFLGIEN
ILLLRGDKAKDDRMFTPIAGGHAHASDLCEQVNRFNEGFFIDGTPIKHPGTPFHYGVAAY
PEKHEEAPNPEMDMAYLKMKQDLGAEYAVTQLFYDNQKYFDFVRRAREAGVTIPIIPALK
PFAKLSQLTVVPKTFHCDLPQELAAEVVKCKTDDDARQLGIEWGIQQARELYASGITSIH
FFTVSAVDSVVAITKALL
>K2KJ72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanibaculum indicum P24|TrEMBL
MSGNLSFEFFPPKTEAMEESLWRAIQRLALLRPNFVSVTYGAGGSTRERTHATVARLLAE
TDLVPASHLTCVNASRDELDTVARSYWDIGVRHIVALRGDAPGDTPGSLGPYTPRADGYA
YASDLVSGLRRIADFEISVAAYPERHPESTSLQADLDNLKRKIDAGATRAITQFFFEADT
YCRFLENARKAGITVPIVPGILPVTNFGQVCKFAKACGAAVPAWMGGLFEGLDNEPDTRQ
LVAATVAVKLCEKLRENGVEDFHFYTLNRAELTLAICRVLGLGARTAAPAPVA
>I4MD15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis 6119V5|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIANTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFNNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VSYIRSKRPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTYLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNAECLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWSNVKPLFTKIG
>A0A2S8F3P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastopirellula marina|TrEMBL
MLSDFYKPGALPISFELFPPKTDKGVRSLMLQVEQLVKHKPAFITCTYGAGGSTRGRTLE
IVEKVKTMFQVPVAAHLTVVGSSVADLRSFLAEAERRGVDYIVALRGDPPQGETTFKPNP
KGLRYANELVELINDEFSELGVLVAGYPEKHVEAPSAEVDLENLKRKVDAGAQVIVSQLF
FRNSDFYSWRERCEKAGITVPIVPGIFPINSLAQISKIAKMCGAGIPKQLFDKLSEKPDD
AQWHKQVGTAYASQQVNDLLDNGVPGFHFYVLNQAEATGKILTALKGHQAKKKSGSPA
>A0A552V7E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium zepuense|TrEMBL
MKVTEHIENANGKTQFTFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYEYKE
LPSGLLEKKVVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VVALRGDAVKSEIYFKPEREGNNYATELVTQIANLNNGIYLDDHLQNTSATNFCIGVAGY
PEKHMEAPSMDSDIYFLKQKIKNGAEYIVTQLFFDNQKFFDFVAKCRKEGIAVPIIPGLK
PIATKKQLNLIPHRFKVDIPDDLIMEVVRAKDNDAVRQVGIEWCTAQSKELVKAGIPVLH
YYSMGKPDNIKAIAKEIF
>A0A319CRF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus uvarum CBS 121591|TrEMBL
MHIKEKLSQNEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPVEKVDAALQAAYKAGCTNILALRGDPPREKEN
WEATDGGFRYAKDLVRHIREKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDNFIDWVKKCRNKGVAVPIIPGIMPIQTYAAFIRRSEWTKTRIPPDWLEAL
EPVKNDDAAVRNIGKRLVADMCRRLLESGLNHLHFYTMNLAQSTQLVLEDLNLLPSEETP
LQRALPWRPSLGLNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGQPKSIRDITHIFVDFLEGKLARLPWSDSPITTEANAIKDDLIE
LNKKGIFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLIPSYLLDDLIARIEKNG
YLTYHAVSKNGNLRTNTNDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQSVVDDWCLVNIVNNDFHNTSSLFDLFKDLNVKDLDTEIAVEDGETK
VHQNGVTNGAEYANGTVANGTTTELPVKN
>F5S502|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingella kingae ATCC 23330|TrEMBL
MSRKQLSFEFFPTRTPEGRAKQVITRKQLSQFNPAFFSCTSGAGGSTRDGTMQAISDILS
EGIAAAPHLPCIGMKAEEIKELLLQYKAMGVKHIVALRGDIPSGIGLGMDGMRYANELVE
LIKTEHGSDFHVEVAAYPEYHPQSRSAEDDINHFVRKVKAGADSAITQYFYNADAYFRFV
DDVQGRGVTIPIVPGIMPIASFAKLARFSDTCGAEIPRWLRLKLQSYADDTASIKALALD
VVTEMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>G9MEA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypocrea virens (strain Gv29-8 / FGSC 10586)|TrEMBL
MDTDRITDKIAALPADGEYFSLEFFPPKTAMGFANLRVRLQRMERALRPLFVNVTWGAGG
STSQKSLELAELCQREIGLTTCLHLTCTNMSQALIDQALEDARALGIRNILALRGDPPRA
EYRDADEPDQAASEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDL
PYLVEKVQAGADFIMTQLFFDIEAYEKFETTLRNHPSGAFKTIPILPGLMPIQSYAMIKR
TAKLSHAKIPEEIMARLNAVKGDDGEVKMVGVDILSELVEQIREIKSRTPGPKGFHFYTL
NLEKSISFILERTKLIPDEAEDEEAVIDETAVGAAAQLTVPKISVNGNVPPRSSSHARTG
RRQSSVGSDPHNRVIVGRAATHPEWEATSTEAGIPAESVNTRANTLAISEGEGSLGREAT
WDDFPNGRFGDARSPAYGEIDGYGVSIHMSVTQAVSLWGHPKVASDINDIFVRHIRGEIS
AIPWSEEDLLPESSIIKAKLEAMNRKGWWTVASQPAVNGLLSSDPTFGWGPSSGFVFQKS
FVEFFLPSADWKILYDKLTSSEVEEVVCFYASNAKGDFVSSDATGGSGRAAMSASTNAVT
WGVFPGKEIVTPTIIEEVSFRAWSEEAFDIWAEWAKVYGRGSDSQKLLDEIREDRWLVNI
IHHDYVDTDALWRLLTN
>R2PQV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus asini ATCC 700915|TrEMBL
MKIRELFQENKTVMSLEVFPPKKESGLETIYDTLQALGSLAPDFVSITYGAGGSGGCNQT
LELAATIKERYGIEPLHHLTCVNNGTEDLSELLAGMKAADVKNILALRGDLPETGAPRED
FCYAKDLVAAIKRDPDFCVGAACYPEGHISQAEDQENYQHLLEKEQAGADFFISQLFFDN
DCFYRMVEEARKAGVTKPLVAGIMPILSKAQVQKMIFMCGSSLPSKLIKLIHRYGDNPQD
LQKASLEYAWQQLGDLVAHGVDGVHLYTMNRPEIALQTFDYLRGGSL
>A0A7S1T3H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetraselmis chuii|TrEMBL
MKISEKMSASIAAGKKFFSFEYFPPRTDEGLDNLMDRMENMVAYGPNFCDITWGAGGSTA
DLTLEIAKKMQNKVCVETMMHLTCTNMPKEKLDEALNVIKEAGIQNILALRGDPPKGEET
FTAVEGGFNCALDLVKYIRDTQGDFFGIGVAGYPEAHPDVISEDTAEQEKAYRGDLDYLK
KKIDAGGEFVVTQLFYDCDKFIKFVADCREMGITVPIVPGIMPIM
>A0A4Y7RVC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelotomaculum propionicicum|TrEMBL
MKYLSKLQKMLDSGHFAVTAEIGPPKHAGAHSIRHHAQLLKNHVDATNITDSQTAIVRLS
SIASGVHILDCGIEPIVQMTVRDRNRIAIQADLLGAYSLGMRNLLCLSGDHQQFGNHPTS
KNVFDIDSMQLIYLMSRMRDEKKFFCGEEIKEYEPRFFIGAVANPFADPFEYRVDRLEKK
IEAGAQFIQTQCIFDMERFERFMEMVRARGLDQRAHILAGVTPLKSWRAAKYIQTGVSGM
IVPDSLVERLKNAADPKKEGIKVCIEQIKHIRENIKGIHGVHVMAIAWEEVVPEIVEKAG
LYPRPQVEFNPEEND
>R8Q305|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VD118|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLGKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPNFIEQGIRLLGGCCGTTPEHIEGMKRAIANVVPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEEPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>B9T9X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ricinus communis|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A1I8NXI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stomoxys calcitrans|TrEMBL
MQVKRRYTHCSFIARSLKRRETIKPKKYSNNNKQPQIFTMSENAITSSTTTLGPLSGALG
AHVLPSSAATATNSTSRYYDMNIRINEDLTASASETGQLKHVINEKIKNKEFFYGLEIMA
RTYEPNVVLDYKSLGPLMPLFTSIVWLGMDYWQVENLADIGAINLARQIKPHMMVLPHFS
CYRLTEDRLRKFLDLNFPNVLSVRGDYYDTQQAYKYSSELVTAIRSIRGDTITIGVAGYP
EGHPECKSVEEDMDNLVRKVSAGADFIITQICFSSRAIIDFIRRCRAKDIKIPILVGIFV
PDNFRMLEAMLRITQIRMPAVELEEYRQHSILGRAQFTEFAIKRAAEMIDAILHSNEVEV
YGLQFFSMNKFENIPKVLEKIMQNKNNI
>A0A5F0MBC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia dentocariosa|TrEMBL
MTTVHPALSYELYPPRSHASCDSLLKTIAELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLALRGDIPSENTRPLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAARLAGVEMPIIPGIMPVTSLTRLTKLCELAGLEVPRELAHRLETASNP
RELHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>A0A1G7FDE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter capsulatus|TrEMBL
MTTPHVSFEFFPPQTLDASFRLWETAQVLAPLKPGFVSVTYGAGGTTRKLTHEAVAAIHK
NYRLNVAAHLTCVDATKAETQEIIDAYAEVGVTEIVALRGDPPKGAARFTPHPDGFASSV
DLIEWLARDGRFTLRCGAYPEPHPEAADTLADVRWLKRKCEAGATSAITQFFFEAETFFR
FRDACVKEGITAKIIPGILPIQSWKGAKGFAQRCGTSIPAWVEEAFDHAIRDDREQLLAT
ALCTELCDNLIAGGVEDLHFYTLNRPQMTRDVCHALGVNPDVVLENVA
>A0A496DY62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. AF39-10AC|TrEMBL
MKVIDLIRDSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNKKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIVHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A543L8Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax temperans|TrEMBL
MNAAKTEATGFPVSLEFFPPKTEEGAVKLRTVRQQLYALHPEFCSVTYGAGGSTQEGTFT
TVKEILSEGVSAASHFSCIGATRQSVREQLAVLKGMGVRRLVALRGDLPSGYGAGGEFQY
ASDLVAFIREETGRDFHIEVAAYPEVHPQARSPEADLKAYVAKVRAGADAAITQYFYNSD
AYFRFVEDTYKLGADIPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLEL
>E1YDF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MYSIRRRPNNKKGENMSIQKRLKNGEFVVLAEMNTPKGVDISRFITDAKRIKGRIDSIVI
PDMDNGVMRMSALAGAVLIQQQGIEAIIHIYGRDRNRMALQGDLLAAHILGIRNLIVVQG
DDMANSDHRTAIPVDDLDELGLLAAIRSLQAGKDLAGFDLDGQPEFYAGCRLAPFSDEAS
MISELNMAKDKIAAGAEFIITPPVFDINQFQKFMQKASYLGVPVIPTVFLIKSVAVARYI
ATNEPGAHISEEIIRRIRKSPDREMEGVKIAGETIAQLRKMAQGILIQAMGWEHRLSAIL
DAAGI
>A0A0T1XQK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Root482|TrEMBL
MAIHTLYPAERGNLRLSFEYFPPKTDEMEAQLFQTAADLCAFDPHFVTMTYGAGGSTKAR
SLTAVRRMIHEMGVANTAAHLTCVGATKVEVDAIVTEFIDSGVRHFVALRGDPQGGIGAC
YEPFPGGYESSAALVAAIRARGDFEISVSAYPEKHPESRDVDADIDMLKRKVDSGATRAL
TQFFFDNDDFERYLERVRRAGIAIPVVPGILPINNLAQVRKFAGLCGASVPDAIIARLAH
LDESPQERLKEATHIAAEQIVDLARRGLRDFHIYTMNRSPLVAGVLDLVGFERRAPASAQ
RSAGAAA
>A0A1M3P0U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. 68-29|TrEMBL
MPAISLEFFPPKTDEQRAQLDQAAQVLKAWRPEYASVTFGAGGSTLSYTGDTVAHLHAVH
GLAVAPHLSCMGGTRAEIRALLDGYKAAGYRRIVALRGDLPSGMASAGDFRYAAELVRFI
REHSGEHFHVEVAAYPEIHPQADDAHADLLHFKAKVDAGANGAITQYFFNPDAYFRFVED
AHKLGVRVPIVPGIMPIANYTQLKRFSDACGAEIPRWIAKRMLAHGDDAAAVRALGAEVV
AQMCRRLLDGGAPGLHFYTLNRAKATRAVLEQLD
>A0A435T3J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.06.1.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A6B2Z0B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID14515|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGAWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A1Y4X7P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus brevis|TrEMBL
MTTRKKDLRAYLKDHLLVGDGAMATQLHGLGVPVGVSFEELCLSNPRLVHEVHTSYYQAG
ARFLETNTYSANRDALSRYGLEHKVARINRLAVAIAREAAQDDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGVDGLILETFLDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYALTDAFSELKAAGADVVGLNCRLGPAELLRSFENTVIPEDALLSVFPNAGRLG
MTDGEYAFKSSPEYFGQSALRLREQGVRLIGGCCGTTPAHVKAIADALESLEPQARVNPT
IVAGDRPTISVQNTREREKPSIVERVKTATTIIVEFDPPRDLDADQFLHGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKSRHGIDPLLHLACRDRNLIGQQSHLMGLNALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMDAAVARLEKKVEAGADYIMTQPVYDAESIRNVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSTEALERMKKVQGEAARLEGIAIAKELVDTAVRYFNGIYLITPFNYFE
MAAELIQYTRQQSSLVRMAQT
>A0A2E0UHA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodospiraceae bacterium|TrEMBL
MSRVPFKERIQTGAPVLFDGGLGTEFYNKGIFINKCFDALNITKAALVKEVHEAYVDAGA
EVLETNTYGANKHKLSGHGYHDKVYEINKRGAEIAREAAGDDIYVAGSIGPLGLQMEPLG
PLSRDEAREMFEEQVKGLLDGGVDLFILETFVYPDELEEAVKAVRELCDLPVIAQMTVND
DATSLTGGSTEGMVRELEETGADIIGINCTVGPAVMLTWLERVRKHTKLPISIMPNAGKP
RNIDGRNIYMSSPEYFGTYAKRFLQNGAQIIGGCCGTTPEHILRMRNAVSHAAVTVDMRD
VAVEKFEKPPDVELIPPEGKSRLARRLHDGHFVTFVELLAPHGVSPQKEIDNARKMYYFG
VDAINIPDGPRASARMSAMALAVQIQREVGIETVLHYACRDRNVIGIQSDLLGAYAMGLR
NILAVTGDPPKLGNYPDATAVFDVDAIGLVNILNRLNHGLDIAGNPIGQPTGMNIGVGAN
PGALNLDHELRRLDWKVEAGANFIVTQPVFDLKVFEAFVKRIEHIKIPLIAGLWPLASLR
NAEFMNNEVPGCHVPDWIMERMRKPETKVEARAMGVQIARETLEEMKPMIAGVQVSAPFG
RVQTVIDLLSTVEYPRAKMFERLGE
>A0A3Q7UK49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vulpes vulpes|TrEMBL
MDQPTPRVLPARVRSSRLGLWTLEAGRVGFSVPPSISRSPAMVKEPRGDGGPTPRSEGSS
SGSESSKDSSRCSTPGLDPERHERLREKMRRRMESGDRWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYLS
GEPNQQGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLKGPSPEREAEAL
>A0A849FF44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MSTPRISFEFFPPHSLDGSFRLWDTVQTLAPLGPDFVSVTYGAGGTTRDLTHDAVKTIGA
HYDLNVAAHLTCVNASRAETLAIAESYAVAGVREIVALRGDPPKGAGTFAPHPDGFADSA
ELVAALAETGKFHIRVGAYPDPHPDAADPTADVTWLKRKIDAGAGSAITQFFFEAETFFR
FRDACAAAGIDAPIIPGILPIENWAGVKKFAARCGTQVPQWLADAFETATRDDRADLLAT
AVCTELCSDLMDGGVENLHFYTLNKPGLTRDVVHALGITPEVTLEKVA
>A0A6S7DNH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter piechaudii|TrEMBL
MSDSTTPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGATRQDLRDILQTYKSEGVRRVVALRGDLPSGMGGDAGELRYASE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVGKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVQVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHADAPLAVWKELAL
>A0A6A4UCV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTTPRISFEFFPPQSLDASFRLWETVQALAPMQPSFVSVTYGAGGTTRTLTHEAVSTIHR
NYGLPVAAHLTCVDATRTETLAIAEAYAAAGVTEIVALRGDAPKGAQRFVPHPLGFANSV
ELVEKLARTGKFKIRVGAYPEPHPDAADSTSDVTWLKRKIDAGASSAITQFFFDADTFFR
FRDACVRAGITAPIIPGILPITSWAGAKRFAHRCGTKVPLKLDEAFTMAARDGREELLAL
AQCTALCDKLIQGGVEDLHFYTLNRPHLTREVTRALGILPELVLEKVA
>A0A5C5AN80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. CD3-5|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>N8UX66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 758|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GQGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLITGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1Y4K2X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olsenella sp. An188|TrEMBL
MRIADKLAGGQTFSFEIFPPKGEMPLECAYVVASEMAADRPDWISVTYSAGGSGNSANTV
PIAASIERDLGVTALAHLTCLGSTRADVDAYVAALDGAGIENVLALRGDRAPGREERDFA
HASDLIAYLRGRGCDLCIGAACYPEGHVESPSEQESFESLYKKQEAGADYLVSQLFFDNE
DFYRFREKCLRHRVRLPVVAGIMPFTSVRQIQRMAFTCGASIPAKVVKRLVLAGDDPADQ
ARAGIEYACEQLVDLAANGVDGLHVYSMNKPGVAHAAREALVACGYLGA
>A0A368MJV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella sp. KYW1333|TrEMBL
MKVTEHIKNANGKTQFSFEILPPLKGQHIQSIFDNINPLMEFNPPFIDVTYHREEYLYKE
VENGLLKKQIVKKRPGTVGICAAIQNKYGVDAIPHILCGGFTKEDTENFLVDLDFLDIDN
VMALRGDAVKSETYFKPEKEGHAYASELVSQISDLNSGKYLDHELQNTTSTNFCIGVGAY
PEKHMEAPSLDSDIHFLKKKIKNGASYIVTQMFFDNKKYFDFVQKCHKEGIMVPIIPGLK
PISTKKQLNLIPHRFHVDLPEALIIDIVKCKDNKEVRQVGIEWCIEQSKELKRAGIPVLH
YYTMGKSDNIKAVASAVF
>A0A2D8Y9K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MALFGXKTKHSXAPXVSQNLEVFLKNFSIEVMPRTAEKVENFKDILPKNTRVYIAHIEGT
PIEDMVDTARRLAXDGFPTMPHFPARXXSNKAMLNDWITRYQGEAGVDQALLLAGGVSKP
HGEYKSSMDLLETGLFDKANFKNIHIAGHPEGNKDIDPDGSRKNVDAALKWKQNFKNKTN
AEMAIATQFAFEAGPIIEWANSIKSAGIDIPIHIGIAGPAKLQTLIKFAIACGVGPSLKV
LQKRATDVTKLLLPYEPIEVLSQLADYKANNPEFNISSVHFFPLGGIKTNAKWVTENGGT
SGIPANQV
>A0A6C1T477|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTTPRVSFEFFPPKSLEASFRLWDTVRMLAPLVPEFVSVTYGAGGTTRKLTHEAVTTIGA
QFGLNVAAHLTCVDATRAETMEIVEAYAAAGVREIVALRGDPPKGQGKFLPNPEGFPNSI
KLIEALAAMGKFTLRVGAYPEPHPEAADTLADVHWLKRKFAAGADSAITQFFFEPETFLR
FRDTCAREGITGKIIPGIIPI
>A0A2N2ACT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-8|TrEMBL
MGLKEKLGKQFVITTELGPTDGTDVATTLEKARSYIKLDGINIHDCPMARMRINSIALAH
IVQAELGVDTIPHFTCRDRSLLGTQADLLGAHALSIRFLLPTTGDPPQHGPFQSSAVYDL
NTMSLIKLIKEMNKGLDAVAKEFKGPTDFMISGTTSAAATNMDAVFSRVRRKIEAGVDFF
QSQPCYDAAKTLSFVEKMKEFGKPVLIGLMPLKTVKMAEYMNDHVEGIEIPDDVMAKIRE
GVSGAKIACEFVEKVYKQIDGIHIMALGDVKASNEIIEHTLGLL
>A0A0B4Y1F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira xiamenensis M-5 = DSM 17429|TrEMBL
MTVKNDIAPQGISRSDLRISFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGST
RDRTHSSVTRIQGETGIPAAAHLTCVGHTKEEIEGIARNYWDEGIRSIVALRGDLPDAGD
KYVPTPGGYPYAVDLVEGLKRIADFDISVSAYPETHPDAPSADFEIEYLKHKIDAGANRA
ITQFFFDNEVFLRFRDKCVAAGITAPIVPGILPVTNFGSLLKFADMCGASVPKRLHWRFE
DLDEDPDTRRMVAFHEAISQVEGLMAEGVTEFHFYTLNRAELTYAICHALGIRGVAQAAA
>A0A5B9E0Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter glycinis|TrEMBL
MPSISFEFFPPKTDEQRAQLDRVAAALQPAAPEYVSVTFGAGGSTLSYTSDTVRGLHQQH
GFHVAPHLSCMGGSRAEIAALLDEYRAAGYRRIVALRGDLPSGMATAGDFRYAAELVRFI
REHSGDHFHVEVAAYPETHPQAEDALVDLRHFKAKIDAGANGAITQYFFNPDAYFRFVDD
AQRLGVKVPIVPGIMPITNYSQLKRFSDACGAEIPRWIAKRMQAHGDDAASIRALGAEVV
AQMCLRLLDGGAPGLHFYTLNRARATLAVLERLH
>A0A1I4DSY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter glycinis|TrEMBL
MPSISFEFFPPKTDEQRAQLDRVAAALQPAAPEYVSVTFGAGGSTLSYTSDTVRGLHQQH
GFHVAPHLSCMGGSRAEIAALLDEYRAAGYRRIVALRGDLPSGMASAGDFRYAAELVRFI
REHSGDHFHVEVAAYPETHPQAEDALVDLRHFKAKIDAGANGAITQYFFNPDAYFHFVDD
AQRLGVKVPIVPGIMPITNYSQLKRFSDACGAEIPRWIAKRMQAHGDDAASIRALGAEVV
AQMCLRLLDGGAPGLHFYTLNRARATLAVLERLH
>A0A292E868|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. ACO-34A|TrEMBL
MSPDIDPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERASVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDQSKFLSGRKLTSPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PLASAKTANWIRSNVPGIHIPDAVIKRLEGAEDQKKEGKQLCIDIINEVKEIEGISGVHV
MAYRQEEYVAEIVHESGVLRGRKPWQREPSPVDALVAERLEAIRGEKLEDQQQLAEKAAS
HPH
>A0A2W5CBH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium faecium|TrEMBL
MPPISLVSPPATAPPTGRAATAPSATGTRPVRPSRDPVGQRSPSAATLPDPTEHLPAPSP
RRRPALSYELFPARTGSSFERLQQTVAQLEHTAPDYVSVTSRTGYQNFARVLELTDHVLE
HTRLRPLVHLTSVGARREHLVAAIEALLDRGVRGILALRGDVPEGHVPEDDEFPFARYLV
ELIREVERDRSALLAGGRLAIGVAAYPVRHPESPTRQHDVEVLVSKARSGADFAITQVFF
DPADYCDLVTRARRAGVEIPLVPGFIPATDSKRLHRLAELSGVHAPRELLHALECAADDA
ERRRIGTRFTVDLIRGVLDAGAPGLHLYTFNRHAEALDVLDALDLDRWSTAGTPDPGTPD
PAATPHQGDPR
>A0A1Y5HJ94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|'Osedax' symbiont bacterium Rs2_46_30_T18|TrEMBL
MVIHDEPTPGEMLPILTGHSSAGRLERVLRAGHFAVTAELAPPDSANPHDVYTRAELFDG
HVDAMNATDGSGANCHMSSVGICALLTRIGYAPIMQVSCRDKNRIAIQGDVLGAAAMGVS
NILCLTGDGVQAGDHPQAKPVFDLDCMSLLETVRGMRDKAQFLSGRKISDPPKVFLGAAS
NPFAPPLDFRPHRLAKKIAAGAQFIQTNYCFDVPRFKEFMARSRDLGLLEKVFILPGVGP
MASARTANWIRNNVPGIYIPDSIIERLAGAKDQKKEGQQLCVELIQELSEIEGVSGIHVM
AYRQEESVAEIIKSSGVLQGRVPWYPGRDQKLLQERARL
>A0A0D2E026|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala oligosperma|TrEMBL
MVNMHISEKLASNLKENKPSFSFEFFPPKTAQGVQNLYDRMDRMHDLGPLFIDITWGAGG
RNSQLTCEMVNAAQSHYGLETCMHLTCTDMERSQVDRALDRARDAGCKNILALRGDPPRD
KEKWEAKDGGFRHARDLVKHIRAKYGNIFDIGVAGYAEGCDDNRDVDVLIDHLKEKVDAG
ATFIVTQMFYDVDIFLNWVRKCRDRGINVPIIPGIMPISTYASFMRRAEWTKCNVPKEWY
EALEPVKNDDAAVRDIGKDLIAQMCRKILDAGILHLHFYTMNLAQSTRLILEELVLTPET
SGKPLEKPLPWRQSLGLNRRDENVRPIFWRNRNTSYIARTADWDEFPNGRWGDSRSPAFG
ELDAYGIGLKGTNEANIKLWNKPKTLREITELFVRFLNGGLERLPWSEGTISAEASIIKE
DLLKLNKRGLLTINSQPAVDGAASSDPVHGWGPPGGWVYQKAYLELLAFPSMIDTIIERL
NANKNLTYYAVNKHGKLITNAKDEGPNAVTWGIFPNREVVQPTIVETVSFLAWKDEAFRL
GEDWAKCYPAGSASRKLVQEMMNECYLVNIVNNDFHNTREIFTVFEGLEAEDLDQVFTDD
GADVQNNPSRDVLNGEASASEIEKNITNANQQRIPFQTNGVAPVK
>A0A355PNG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp|TrEMBL
MKIRDILAKNEPTLSFEVFPPKTEDKYESVEAAASEIAKLNPAFMSVTYGAGGGTSQYTV
DIAASLKAKGVTPLAHLTCVSSTREKVHSVLDQLKAEGIENVLALRGDIPKDGKVEKDYR
YASELIAEIKASGDFCIGAACYPEGHVESVNKTEDIQHLKEKVEAGCDFVTTQMFFDNNI
LYNYLYRVREKGITVPVIAGIMPVTNVAQIKRICSMSGTYLPARFKAIVDRFGDNPAAMK
QAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNSLSEIIR
>A0A6I4YTX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharibacter sp. EH611|TrEMBL
MPKISFEFFPAKTEKGAAKLLQTAQTLAGLNPEFMSVTYGAGGSTQERTLKTLRDMVGLV
SVPMAGHLTCVDASKGEVDDVARAYWDSGVRHIVALRGDPRPVDGKARSFEPHPQGYRNA
AELVAGLKKIAPFEISVAAYPETHPEAQSPESDLDNLKRKFDAGADRAITQFFFQADRFL
HFRDRLAAHNMTKPVVPGILPLSNPAQAWGFAEMCGASVPQDLRHLFAGLEDDVAVRTHL
AAVMTDRMCQKLLDEGVDHFHFYTLNQSATCAAVSRLLGHFPE
>A0A840UQE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoprunum benzoelyticum|TrEMBL
MEAAHRSDTGRKSDKPYYLAAEIDPPKGTNLQGFVESALSLRGRVDSIRVTDSEHAIMRM
SPLAPCLALKEKGIEPVMVVNGRDRNRISFQGDLLGASALGITDIVIREGHDPAEGDQPV
ARTSGDLDLRTMLKCASSLNAGHDLGGEKLDGAASLRIGVSLELSDDASRNRDQIDLIRR
MQEFGVSSVCLGPTYDINIIEQFLPVAEETGINLYLSVMLLKSVTMIRYLNNLKGVPSIP
QEYLKKMMDAPVKQDAGLTIGADFIREIAPIANGIVILAIGWKDRLPDFLDLLGR
>A0A6C7DCI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 56:b:[1,5]|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A099T1H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanococcoides methylutens|TrEMBL
MLSTFNDALNSDRFIVTAEVAPPKGIDISAVLEDADLIRGWVDAINITDNQRAVMRMSPV
AVGKLLMDAGLEVVVQFTCRDRNRLALQSDILAASALGISNLCVMTGDYPTKGDHAGAKP
VYDLDSVQLLSVITKMMGGHDMAGNELAGAPSFTVGAVSNTDAARRMQMIKLQKKVDAGA
QFIQTQAVYDVEVFGEFMDSFSHPDVPVIAGIIPLRSAGMARFMNANIPGIRVGDEMISR
MEDAEDPVQEGLEIAAESIRELRKMCRGVHLMPIGGNSNTSKLLEMAGISALQ
>A0A134CDD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera hutchinsoni|TrEMBL
MSVKNKTTFSLEVFPPKKEMPLASVYPTLTELSVLHPDFISVTCGAQGTGSNRTAEIAAT
IKEQFNLEPVAHLPGIYLTKEEVCNTLKELKKHRIHKILALRGDMTPEKEPAHDFAHASD
LIRFIKKESPDFHIIGACYPEGHVESKRPALDIIHLKEKVDAGASSLISQLFFDNTLFYR
FLERCEIASIHVPIAAGIMPVTNKKQIERMVSLCGATLPLHYQHLIAKYGDNPVAMRDAG
IAYAIAQIIDLLAHGVDGIHVYTMNNAYIAQKIADAIRTLL
>A0A1W9MV74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium IS3|TrEMBL
MKLTELFDKGEFVITSEVGPVKGCLRSQTTGKLPQCAAEAEMVRGHVHAINVTDNQSAVM
RLGSLAASVRLKERGFEPIYQMTCRDRNRIALQSDLLGACSLGIDNVLCLTGDYTSLGDH
KSAKSVFDIDSVQLLKIAKGLNDGHDMMGNALTQSTNLALGAVVNPNFEPLDLQLLKMEK
KIEAGAQFFQTQAVYDPAVFEKMAKKTEKFGVPVQYGVVVVKSPQMGKFMNDNVSGINVP
EWIIKEMGSVSKEDRKKKAIEITIKLIKEIRHIVQGVHFMPLGWSDIVPEIVKAVNG
>T4W3I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraclostridium bifermentans ATCC 19299|TrEMBL
MSLLREALESGKFAITAEMAPPKGIDLSHLVECAKAVKGRVHAVNVTDFQSAVMRTTSLT
TCKLLKDEGLEPVLQVTGRDRNRIAIQENYYQLVCLE
>A0A0S7ZQA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium DG_61|TrEMBL
MSFFEDLTSSKFLVTTDVIPPKGVDFSGVLARLECVAGKVNAVNVVDLPSAAMRPSSLPV
AVILKKRGFEIILQMTCRDRNRLALQADLLGAYMLGIKNILAITGDKIDLSDDPAAKPVF
DLDSIALLKTAVQLEEGKDLAGNILKGAPSFCMGAALDPGYHPVEQEIERMWQKVEAGAK
FLQTQPVFKAEEFAEFMKKIGNAPVPVLGGILLLKSARMAHFMNKNVPGVEVPRDIVSKM
EKTKNPIETSVEIAGRLINEIKGICSGVHIMNINWEDKIPLVLDIAGLK
>A0A554V7J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Skermania sp. ID1734|TrEMBL
MSFDPVRGRASKGWVSHTPSIVDRLRPCADGLVPFSVEFSPPRDAAAEARLWRAVREFER
MQPAFVSMTYGAGGSTRDRTVRVTGQLAAETTLLPVAHLTAVSHRVSELRAMVGAYADCG
IRNILVLRGDPPGDPMGEWRKHPDGVEYADELVRLVLDLGDFHVGVASFPEGHPRSPDLE
HDTEYLVGKLRAGAEYSITQMFFDVEHYLRLRDRVTAFDAEQGAKPIIPEIMPITSLRSV
RKMLQLSGSALPRELDERLARAAGDGPEEDRAAVREVGIEVATTMCERLIREGAPGLHFI
TLNFARATSEVLANLGYSVHARA
>A0A6N7SS83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactonifactor sp. BIOML-A7|TrEMBL
MNITELFQRGEFVVSAEVGPPKGTNIDHLVEEAKTYLTGVTAVNVTDNQSSVMRLGSLAT
CKVLKDEGLTPIYQLTCRDRNRIALQSDLLSAAMLGIENLLLLTGDHTKMGDHPQAKPVF
DLDSVSLIHTVKMLESGYDLGGNELVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVMAGA
DYFQTQAVYEPEKFIEFMEKAKQFGKPVQLGIVIPKSVGMARFMNANVAGIHVPESMIDE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAGI
>A0A7G9R4X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycicoccus endophyticus|TrEMBL
MAHYGGGGRPEHLVASIPARLREPRPSVSFEFFPPKDDAAEAALWDAVRRLERVRPAFVS
VTYGAGGTSQDRTVRVTARIADETSLTPLAHLTCVGQSVADLRRVVGNYAASGVRNVLAL
RGDPPGDVRGAWTPHPDGLEHAEDLVRLVRGLGDFTLGVAAFPDVHPDSPGLEHDVDVLV
RKADAGAEFAITQMVFDAESYLRLRDRVAARRDLPVTPGLMPVTSYRQTQRMSELMGTPL
PPQVVERLEAVKDDPAAVRAVGVAIAVELGQRMLAEGAPGLHFITMNRSTATLEVHDALG
LEP
>A0A8D9WZE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella ceti M13/05/1|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A1M7Z857|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthobacter soli DSM 19599|TrEMBL
MTDLPTPDSPTSGHTRLSRAVGDAPINVSFEFFPPKTDEMEKTLWTAIQRLAPLAPNFVS
VTYGAGGSTRERTHSTVARIVRETALKPAAHLTCVAATRAEVEDVVRGYREAGVHHVVAL
RGDPPEGPGAVYHPHPDGFASTPELIEGIRAIGDFEVSVSAYPERHPASPDWASEIDLLK
RKVDAGATRAITQFFFENDLYDAYVERVRAAGISIPIVPGILPILGLAQVTRFAERTGAS
VPAWVARRFEGLEDDAGTRQLVSAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLL
GLRPQPAAVAA
>W1WZI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. DORA_A_3_16_22|TrEMBL
MTLREKHQQGKFTITVELDPPKSSSAQKVFDQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKDIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNSGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNGA
HFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A0X8JRL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomicrobium orale DSM 12838|TrEMBL
MRIAELLQRREPFLSLEFFPPKDRAQWPGFFDVVRELKVLAPVFCSVTYGAGGSTRHNTL
EIAARLKQEYMLEPLLHLTCVGAHRTGLSSFLEDVADSGCENILALRGDPPRGETTFIPD
SEDFRHGCDLVHFIRDGFPRFCVGVAGYPEKHPEAPSMERDIAWLRHKVQCGADFVITQL
FFDNNAYFRFVDQARSAGVTVPIIPGVLPVRNLAALKRMLGFCGASVPEGYMRDLEHVQH
VYGDSGVRGLGLGFAKAQIRDLLDRGAPGVHLYTLNRADTCLEIWKDSTVRDTHSDC
>A0A4V5NW88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrimonas aestuarii|TrEMBL
MGFHHAQQLEALNERLSHLKDIQVSFEFFPPSSEEMEKTLWQSVERLQPLNPRFVSVTYG
ANSGVRDRTHKVIEKIHKDTNLVAAPHLTVVDASEEELRQLARNYWQQGVRHIVALRGDL
PEGQGRPDRYASDLVALLKQEHDFEISVAAYPEVHPEASSPQADLINLKRKIDAGANRAI
TQFFFDIEAYLRFRDRCAAAGIDAEIVPGILPVTNYRQLLKFSDFAKVHVPNWLHHMFDG
LDDDPATRKLVGANVAIEMTKVLAKEGVQEFHFYTLNRAELSYAICHALGVRPSC
>A0A3D5BTJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomicrobium sp|TrEMBL
TQLFFDNDLYFDFVDRARGAGIDVPIIPGVLPVQNLAALKRMLAFCGATVPEGYMRDLEH
VQAVYGDSGVRGLGLGYARSQVRNLLDRGAPGVHLYTLNKADTCLEIWKDFAGRQGRR
>A0A5J4PFU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
MKIIDLITDSKHTAFSFEILPPLKGTGIGKLYDMIDTLREFNPKYINITTHRSEYVYTDI
GNGLYQQN
>B3H1J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus pleuropneumoniae serotype 7 (strain AP76)|TrEMBL
MSYAKEIDHLNHTLADLNGNINASFEFFPAKNEKMEMLLWDSIHRLAPLKPKFVSVTYGA
NSGERKRTHSIVKRIQQDTGLAAAPHLTGIDANPEQLRIIAQDYWENGIRHIVALRGDKP
AGYAKKSFFAKDLVKLLKEVANFDISVAAYPEVHPEAKSAQSDLIYLKQKVEAGANRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVTNFKQLQKMAKITNVKVPHWMHKMYEGL
DDDQTTRNLVAASIAMDMVKILSKEGVKDFHFYTLNRSELTYAICHALGVRPT
>A0A2D8P7N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritimibacter sp|TrEMBL
MKTPRISFEFFPPKNIESTFRLSDTVRDLAPLDPSFVSVTYGAGGTTRELTHDVVATIHK
NYGLNVAAHLTCVNATRAETMEIVDNYARAGVSEIVALRGDPPKGSSGFTAHPDGFANSV
ELIEALATRGDMNIRVGAYPDPHPEATCDTSDVDWLKRKIDAGATSAITQFFFDAETFFR
FRDKCEKAGIDAPIIPGILPIQSWSGVKKFAASCGTPVPVWLDEAYTRAERDGRDRLLSV
SLATELCTELLEGGVEDLHFYTLNKTDMTRDIIHALGVTPKVTLQQVA
>A0A543PI91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus colisei|TrEMBL
MNRAITVREPAARASLKKAFETLGYEVIPFKKTEQAVLQHVPKDVRLTVTASAAKGQDVT
IDLTVALVGHGYTVAPHLSAQQIRDRAHLAEIVARCREAGVTEVFVVGGDPTDIPTEFRH
AHDVLVALHEMDHGFTDIGIAGHPEGHPSASEDVLFQALKDKAPLATHIKTQMVFDPKVI
LDWARELHRRGIDLPVHIGVPGAVHRQKLLRVSSGLGIGESAKFLKKQQTLLWRFFLPGG
YNPAKIIKGLAPHMGQPDNTIAGFHVFTFNDLEPTEEWRKKTLQSLS
>A0A1I4HEQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum salsuginis|TrEMBL
MPTASQHRASRDGFRPIRVSIEFFPPKSEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETNLKPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPAEGVG
YAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFDNEIYLRYLDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLDDDVETRRLVAAAVAAEQVLDLVDQGVEDFHFYSMNRSDLVYAICHLLGLRSQTPKV
AAAKAA
>A0A5B0FBG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ANT_J12|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A496MTD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp|TrEMBL
MTQQPLPEPTPARYQRSITDVISSPAPGRIPFSVEFMPPRNDEAETRLRTAAETFHDLGV
AFVSVTYGAGGSSRDRTMRIAQDLARMPLTTLVHLTLVGHTEAELMEILSDYASLGLSNL
LALRGDPPGADPLGEWTPVPGGYRYAEELIWLTKRLEATKHFQVGIAAFPEGHHQSESLA
ADTKYTLAKLRAGAEFSITQMFFDVDYYLRLRDRLAADAELGSRPIIPGIMPITSLKSVR
RQLQLSGAKLPARLEERLVAAAAGDEEANRDEIRKVGIEESTLMAERLIAEGVPDLHFMT
MNFARATQEVLHNLGMAPAWGREHGHDAVR
>A0A1F3D139|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWA2_40_15|TrEMBL
MDAEPASRLARELKEGKFVIATEVTPPLGASTGKLTRDIESVMPYVTAINFTDSSSARPK
MSSIACSCIAIKLGAEPVLQITARDTTRSGLQGDIVGLNGMGIYNVLCISGDSPIIGPTP
VSSMNFPDIDSVQMLWILRRMRDEGIYLDGRRMKESPKLFLGAATSPFASDPELQAIKDT
KKVNAGAQFFQTNLIFEPDRLDPWLEQLYKRNILDKVYIMIGIAPLKGYKVAEYLHRRVP
GVRLPESILNRMQKAGEGAPEEGVQITLELIESIKKKQGVNGIHIMTLGWESVVKRIVNE
SGLHQT
>A0A1H7VWS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter orientalis|TrEMBL
MKVTDHINNAQGKTLFSFEIVPPVKGRNIQELYNNIDPLMEFKPPFIDVTTSREETIYVQ
KEGLLDKHTTRMRPGTVGICASIQHKYNVDTVPHVICGGFTKEETEYMLVDCHYLGIENV
MALRGDARSEQKYFEPTDGGHPFAIDLVKQIHDLNSGKYLHETVETDHTGEFCIGVAGYP
EKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEAAKNIGITVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVDSCTSNKDVRAVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAKELF
>A0A2N3WA29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis niigatensis|TrEMBL
MTSVIERLRGDGPAFSVEFFPPRDEADEAVLWKAIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLCPMAHLTAVDHSVSELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPEGLTYAEELVELVRSLGDFCVGVSAFPYGHPRSPDLESDTKHLVRKFRAGADFAIAQ
LFFEAEDFLRLRDRVAAAGCDALVLPGIMPLTTLRTLHTTIKLSGAPASQRLLDRLEPLS
DDPKAFRAAGLDWVTELCEKLIAEGVPDLHFYTFNRSKATREVVTRLGLVPARA
>A0A4R5MIK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter changchengzhani|TrEMBL
MKITQHIQEAKKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKEQ
DNGLLQKVSYRKRPGTIAICAAIIHKYNIDAVPHLICGGFTKEETENALIDLQFLGIDNV
LALRGDARAADKSFIPTKGGHCYATDLIEHIKNHNDGKFLHEDIETFNSDFCIGVAGYPE
KHFEAPNLNADFKFLKKKVDAGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKPI
STLSQLTVLPKIFHIDLPEELTDALSHAKSNAEAKEIGTESMIKQCKELMDFGAPVLHFY
TMGRPEQTKKIARAIF
>A0A0R1QHB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus mindensis DSM 14500|TrEMBL
MTETNNAPTLSFEVFPPNSDVGVGKLTDTLDQLKGLEPSFISVTASNHKLDYEKTTIDLA
KYVHDTLQCPTMVHMPAAYVTKKEVKDVLDRLEKMNINQVLALRGDIVDGYVPETDFKYA
SDLTSFIKEQKPNFQVSGACYPEVHPDSKNRVDDIKHLKDKVDSGCDQLITQLFYDNEQF
YRFQEECAIANINVPILAGIMPIVNRKQALHVIENCSAHLPKKFVNILDKYKDNPVSLKE
AGIAYAVDQIVDLVTNDVQGVHLYTMNKSDTAKHIFRNTASLFDLEVPVEE
>A0A2S6Q7C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha11_Bin1|TrEMBL
MSALSDTIAAGHFAITAEITPPLSANPIDLLAKSDVLKGKVDAVNVTDGASARAHMSSVA
AAYLLLQSGIEPVLQLTCRDRNRIALQSDMLGAAALGVENLLILGGDDPSAGDQPDAKPV
FDYKSRELMECAHQMRSDATLPSGREIKVPPKLFIGGADTPMNPADDRWNPEALIAKINA
GAGFLQTQFCFDPEIVREYAVGLIEQGISEKAGVLIGIGPLASAKSARWMRENLWGTTIP
DELIDRLEGAENQKAEGIDICAELIANYSTIEGISGVHLMAPLGVDAIPIAIEKSGVRH
>A0A517U478|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacipirellula limnantheis|TrEMBL
MTIRDAYGSNRFGLSFELFPPKSAEGMASLFQHVDELVKFDPSFITCTFGAGGSTQDRTL
DVIAGVRDKYAVPVATHLTCVGLTEPQIGEYLARALDRGVENVVALRGDPPKGETAFKPI
AGGFSYANELVGFIRRDFPQMGIAVGGYPEKHQEAPSLDVDLENLKRKVDAGADVIITQL
FYNNDDFFRLRDRCDGLGIAVPIVPGLLPVTNLAQIQRIASLCGAKLPSRFVTALEQQSA
DAAGQFSVGVEFAIEQAVGLLEGGIPGIHFYVLNKSEATRRVLNALPQFAEE
>A0A0M4R8C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas versuta|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETADHFHIEVAAYPEMHPQARNFEDDINNFVRKAHAGADSAITQYFFNADSYFR
FVERVRAAGVTIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIQSIQAFG
EQVISEMCERLLVGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7X0VID8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella nanjingensis|TrEMBL
MLRQKIARREPGILTYGITPPKATHTEDKIAEIAQKQVDRLRNCAIDGLILYDVQDEADR
IDEDRPFPYLATVDPTRYSKDYLQALDAAKIIYKVVGKQSKEELADWIRADEGKDRFSVF
VGASSSRQAVTMRLPEAYRLGAELNGRLQVGGVVIPERHESKGDEHLRAASKQESGCAFF
ISQAAYDVEASKNFLSDYYYHCREHGIPMVPILFNLAPCGSQKTLAFMKWLGISIPRWLE
NELTYCNDILDRSVRLSRKIFEELFEFGLEKGIPIGCSVESVSTRKVEIDASVDLLREMK
LLMENRLQTEVAKV
>A0A1U8ZIT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. aurantifolii|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A3B8YCF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MKPSLSFEFFPCKTEAGHEKLIATARQLAGYGPEFFSCTYGAGGSTRDGTYRTVRQLNDE
VGVPTAPHLSCVGDSKAKLRELLQQYREAGINRIVALRGDLPSGMGLSGGGELRYASDLV
AFIREETGDHFHIEVAAYPETHPQARSFTDDVRNFVYKMEAGADRAVTQYFFNADCYFHF
VERVRKLGVESPVIPGIMPITNYSKLARFSDACGAELPRWLRKQLEAYGDDTQSIQAFGE
EVMTALCERLLEGGAPGVHFYTLNQAEPCIAIWRNLGF
>A0A3E0CP15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. BL6669N2|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLITLKPKFVSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLDNFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCGRLIDAKVPGLHFYTLNGAAATKAICERLGA
>A0A5P2C2B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces venezuelae|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTFSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGDWIAHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSPDWDSDTRHFID
KCRAGADYAITQMFFDPEEYLRLRDRVEAAGCATPIIPEMMPVTNVRQLDRLPQLSNAVF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHQA
>A0A1D7V2Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira tipperaryensis|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSRVNPDFVTVTYGAGGSTRDK
TVQIVTEISKNYSFPTASHFTCVGANQDQIREILKGIRSQGIVNLMALRGDPPRGEGEFR
KTPGGFENATELISFIRSEKMDFCIGGGCYPEKHPSAKSLEEDVRHLKLKVDAGTDFLVS
QLFFMNSAFENFLNLVRKVGIQIPVIPGIMPITSFSQIERFKSLAGCEFPSALIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLEMGVPGIQLYTLNQSHASYDIVRELKG
>A0A2S1LBZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium faecale|TrEMBL
MKVTQHLENAKGKPLFSFEIVPPQKGSNINDLYENIDPLMEFKPPFIDVTTSREEFVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGVDAIPHVLCGGFTKEETEYLLVDCHYLNIDNL
VALRGDPMKGEKYFEPAKGGHAYASELVKQIKAMNSGQFLHDTMPMKSAPDFCVGVAGYP
EKHIEAPSLEADLKRLKEKVDAGADYIVTQMFFDNQRYFKFVESARAMGITVPIIPGIKP
VAVKRHLQLLPQVFWLDMPESLISDVENAKDNLAVRQIGVEFAVQQSKELIEFGAPCVHY
YSMGKSDNIYNIASQVF
>A0A2P7BH72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium sophorae|TrEMBL
MSFFRQSRRPDLGTNIRVSFEFFPPKTEVMEERLWETVTRLAPLTPEFVSVTYGAGGSTR
ERTARTIKRILTETDVNAAAHLTCVDATKEEVDTVVREFAAMGVKRFVALRGDPANGVGA
NYKPTPGGYENGADLVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVEKVRRAGIYIPILPGILPIHNFTQVTNFCSRAGTHIPGWLTERFD
GLENDPQTHQLVASAVAAEQVLDLVERGVQDFHFYTMNRADLAFAICHLIGIRPGSGALE
GALAGAAA
>A0A0R1LN84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schleiferilactobacillus odoratitofui DSM 19909 = JCM 15043|TrEMBL
MNRFYQSLDTLAGLKPAYISVTYGAGGSSNHADTVALCQLIKARYGIEAVAHIAGVNFTR
ASVQQYLAKLQDAKVENVLALRGDLPADGVIKGDFQYANELVSEIKQDGDFNVIGACYPD
VHPEAADSVDDIRHLKCKVDAGVSQLITQLFFENEHYYQFLERFELANVNVPIQAGIMSV
VNERQISKMATLNGVTLPPKFMKMMTHYQDNPVAMRDAGIAYAVDQIVDLLSEGVDGIHL
YTMDNPVVTERICSAIATLI
>A0A5P2DJG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces venezuelae|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMADWVAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A1V4MC27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|delta proteobacterium ML8_D|TrEMBL
MDSGHEAKWMNRSFAVTFELVPARASKGKAIDEILRFAREAANDGLISALSITDNAGGHP
ALSPGALGSEIMDFGIDSIIHFSCKDKNRNLVESQLFVLDRSGIKNLLVLTGDYPRYGFM
GNAKPVFDLDSVQVLGMISDMNQGFVLNSKAPFGGVQLAPMCFHAGCVVSPFKRLESELI
PQYLKLKRKVHAGASFVITQMGFDVRRFDELRRFMDREGLKVPLLGTVFIPTVKLARIIS
RGEIPGCVLPGGLLERMEQEALSNDRGEGARLERAARLMSILKGLGYEGAHISGPFLKYA
HVKWVVERANEIGERWKHFVNQFLFPEEWNFWYFKEDPETGLNCDELNPVSDAGLSLKDS
MGLGLGRLFHGLAFEPERPFFNSLQRMAEWIDGSPSKRYFTSFEHRVKEWLYDCRRCGDC
TLGEMGFLCPQSQCPKSLLNGPCGGSRDGWCEVWPGRRRCFYVRVYERLRVLGKQESLAG
PRVPPRDWALDSTSSWLNFYLGRDHHRRR
>A0A7W2Z8A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. RHBSTW-01064|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A0N4TET2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brugia pahangi|TrEMBL
LLRFEALLCGTLFFQFFPPKTTNSVANFFARLDRFREGNPMFVDIAWHFGSDPGNISSET
SSSSVAAGCLDYCGMDTMLHITCCPYTKEQSIRHLEQSKALGLKNILALRGDLPRQVRIF
DLIAID
>A0A013SHY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 742879|TrEMBL
MSHLSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YSDSIEKVLHFSGKARDIQDFERFLQQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQVKSFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTER
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLSLKALEELWNSLWQIT
SGKEFSPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALVAK
VLIKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A3N5R2T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon|TrEMBL
YNNYFDNKTINKNIDLFLSRTKRISEFVDGIHLTDNVLGIPIVSSLIIVSMLKKMVIAKP
ISCTCRLYDKNLISVLQFVTDSIIAGVYSILILRGDEPVIGNKIIDIPPTKIIKTLSEHN
FNNFIKLDLSFPNRIENSAKIKNKLEARPRAFVTQSISSIENLKAIVDVSRPFGIDVIPC
IMCPSKRNEVSAKNIGLDWSSYVNDPEKFIHEAGNLTHKVLLCSPNSFEDGLDLVKRLKK
N
>A0A0M0BQX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|miscellaneous Crenarchaeota group-15 archaeon DG-45|TrEMBL
MVNKRPAHSNLVKELRSGRFVLTGELEPEKTTGLEEILASARAMKPYVVAANVTDNPLSM
AFMNSLVPAYIVQREVGLETVYQMVSRDRNRIALVSDILAAAHLGIRNILALSGDHTVLG
DNKGALPVYDLDSAQFVYLISKMVDEGVDLAGNEIHGDVDINIGIAANPNADPLEPEVLK
IGRKVGLGVDFIQTQTMFDIDLVKEFLGEIERFNCPCLVGIFPLKSFGIADFFDKYIPGV
SVPEDLLEEMRRCKEEPDKDKRQGRYDEVNIEFFEPFIKEVRKTTKAAGIHVMAVFYERI
FEPLLRTMA
>A0A5N9EFI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MTVKDKFIFGVEVETTRGLIKDLSVDTRINHAIEMSRSGHLDFLAVTDNPGGSSHIQPEF
LAQKLSGVDINLIVNVSCKDSNRNAIGSRLWTLASEGIFDILALTGDYPTEGYSGSSQPV
FDIDSVGLIDLMRSMSLEMENNGEKTLFNPGCVVSPFKLTEAELMTQLYKLDLKLKSGAK
WAVTQIGYDSHKLYELKNWFKQKSINRPLIGSVYILNRGSARFFNKWGIPGVYVSDSLLK
IAENQATARDKGKKYFNEFAARQISVLKGLGYSGVYISGKPTPQRLDEIINIYNSYSKND
WKQFADAINFPQDDEFYLYRKPKTFNTYHSEYSEKYLESSKKARTFKQRLKSPIRYRIGK
FIHDSFFSIDAKGYKIGHVFYKYVRGKKRTSQAFHALEQLSKVSLYGCKDCGDCSLPDIA
YLCPESQCVKNQRNGPCGGTRAGMCEIPDKECIWSRAYYRLKPFGDETNMLSRPVVFRDS
KLNGTSAWSNTFLGLDHNTKKNKIR
>A0A7K8FVW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Struthidea cinerea|TrEMBL
MVNETQHTFSASSSSRSDGSSSSGSESLKDNLRCSAPVFDADRHERLRDKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKNDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETSLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIKQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>G9QKJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus smithii 7_3_47FAA|TrEMBL
MGFLDRLKTEILTADGAMGTLLYSYGIDYCYEELNITKPEIISKIHEEYILAGADVIQTN
TYSANAVKLRRYGLEENVKQINKAAVRLAKKAAADHGTFVFGTIGGIRGFRKDTCSLADI
KEAFLEQAESLLNENPDGLLLETYYDFEELTTVLKIARKLTNIPIIAQVSMHEPGVLQNG
LSLNEALHRLEDHGADLVGVNCRLGPYHMIQALEKATLPKKAYLSAYPNASLLDVKDGRV
IYESEAEYFGRAAVKLRNQGVRLIGGCCGTTPKHIEAVKKALSGLSPIHQKSVKPEKPII
VKEPPAPLDPPLHELAKKKRTIIVELDTPKHLDTFQYFKGTQVLKEVGIDALTMADNSLA
SPRISNMAMAALVKANQHIRPLVHITCRDRNLIGLQSHLMGLHTLGIHDILVITGDPTKV
GDFPGATSVYDVSSLELISLIKQLNNGISFSGKPLKQKTHFSVSAAFNPNVRVLEKAVKR
MERKIECGADSFITQPVFTKEKIKEIYEATKHLNVPIFIGIMPLTSLKNAEFLHNEVPGI
KLSDEIIERMRAFDGDKEKSQQTGIEIAKELIDTALRYFNGIYLITPFLRYEMTADLARY
IREQDAKKGETVHAEITTSN
>A0A8C5E1C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gouania willdenowi|TrEMBL
MGKQTPHGDGNWQSSKSDSSGASGGDSSKESSRCSTPVLDADRSDRLRDKMRKRIESGDH
WFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVN
YCGLESILHLTCCNQSKEKITAYLNKAKHLGLKNIMALRGDPVGSEWEDEEGGFNYAIDL
VKHIRSEFDDYFDICVAGYPTGHPEAETYEADILHLKEKVDAGADFVISQLFFRADTFLK
FVNDCRAIGIKCPIVPGVFPVQGYQSLRQLAKLSKLEVPEEITRVIEPIKDNDAAIRNFG
IHQAVEMCRLLLDSGIVPGLHFYTLNREVATMEVLRQLGLWNEDPRRPLPWAMSAHPKRK
VEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALL
QMWGEELMNEQSVYEIFTCYITAQSNPCGHKVLCLPWNDEPLAPETNLLKDELEKVNRRG
VLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKILKKYEPRVNY
HIVNVNGRNWTNANDMQPNAVTWGIFPGREIVQPTVVDPVSFIDVLIVKLWCRFNGRSIT
PQSADQIRNLHNDGTMFT
>A0A6A6H2Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Viridothelium virens|TrEMBL
MEKITDKIAALPPSSHYSSLEFFPPKTSMGFSNLQQRLERMSTALRPLFVNVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRSLIDEALEQAKVLGIRNILALRGDPPRSNE
YREEGMPPLDGDHEDEFVWAVDLVKYIKRQHGDYFCIGVATYPEGHSDESHPEKQDPAFD
LPYLIEKTRAGADFLMTQLFYDVKAYQEFEKMLREDPSGVFKDITIIPGLMPIQSYQILR
RTTKLSHAKLPPDILSRLDAVKSDDEAVKRVGVDILSEIVETLKSTPSPSSQPRGFHFYT
LNLEKAVAHILERCDLIPPSTPTPAAIDITPDDDDDGTTDTAIDDSFTTASSHVLVNGTH
NNPLTAKSRRRLSSLNSAPHNRVIISRPSSPSATSTTTTSAAQHEAPEDEAGIPRGEALN
SRAHTLAISEGEGALGREATWDDFPNGRWGDARSPAFGEIDGYGGVSLHVSVGAARELWG
WPVSREDVSEVFRRYLKGELRAVPWSVGSADGGEGLSKETATIRRELLGLIGRKGWWSVA
SQPAVNGVRSGDEVFGWGPRNGFVFQKPFVEFFLGRKDWEGLRRKLEGREEEVTFFAGNA
AGDFEASDAKSVNPVTWGSFSGKEIITPTIIEAVSFRAWCEEAFGIWGEWERIYPVRSAT
AKLIRSIREDVWLVNIIHHAFMDKDAIWKLLLED
>A0A3P7U106|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brugia pahangi|TrEMBL
MLRFEALLCGTLFFQFFPPKTTNSVANFFARLDRFREGNPMFVDIAWHFGSDPGNISSET
SSSSVAAGCLDYCGMDTMLHITCCPYTKEQSIRHLEQSKALGLKNILALRGDLPRQVRIF
DLIAID
>Q476T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197)|TrEMBL
MQDRYYSFEFFPPKTAEGAEKLRNTRAQLAPLNPKYISVTFGAGGTTQQGTLDTVLEIQR
EGIEAAPHLSCVGSSRESIREILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFQIEVAAYPEYHPQAKSPRHDLENFVRKVKAGANSAITQYFFNADAYFRFVD
DARAMGVDVPIVPGIMPITNYSQLMRFSDMCGSEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAGGVPGLHFYTLNAAGATKAIWQRLKL
>A0A0H3HYT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium parmentieri|TrEMBL
MIITVTVNGVAGMSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWNSIDRL
SSLKPKFVSVTYGANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWQ
SGIRHIVALRGDLPPEGGKPEMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLIN
LKHKIDAGANRAITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTN
VRVPNWMTSVFDGLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICH
TLGVRPEVAC
>A0A5N9GGH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MHRFIQRIPSQTARVAWISDRPATNSRGAPVVKITEGCFEATGHTSIICDFSPPRSGDSA
VVTQAQIDADFISVAYNPGRAVRTNSAMLAAAIQQSGKDAVFTLATRDMNKLAVQSLLLG
AQLLGLQNVVVVQGDLFGEQDQARVATVNDYHSTGLISAIVQMNQGQDFKEAELRAPSDF
CIGGTVDLGRGIEEEAQLAVRKVQAGAEFLITQPIFNVDHVARYRESYAYNAGKAGTLPI
YFGLQILEQDGVLFSSVPESVRADLEGGRSGVDIALELYQEFQKARLNNVYLMPPIKRGG
ARNYEAAKEFLTLINKI
>C5DPF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229)|TrEMBL
MSIRELYESKDGPTLSLEFFPPKTETGKQNLLERMERMTALGPLFATVTWGAGGSTAEKT
LELASLAQKNLNLPICMHLTCTNMDRNIIDDALTRCKAAGIHNILALRGDPPIGQDWSDL
EASQSEFKHAVDLVRYINYRFPNEFCIGVAAYPEGHCEGEAEGNEQNPWKDLPFLKEKID
AGADFVITQLFYDVDKFLQFEQMFRQHISTDLPLIPGLMPINSYLLFNRAAKLSHASIPS
SVLQKFPPEIQADDDAVKSIGVDILIEIIETIYKATHGRIKCFHFYTLNLEKAVAKIVAT
SPTLSDTLDVVEDENDEAATSEPEEQDQEGDIVLEDANVKNLIEDNRKRRRQSSTVSNVS
SELTSNRVIIGKKNQHGVGAPTRKVVISISQGSGTLGRDATWDEFPNGRFGDTRSPAFGE
IDGYGPTLKVSNKKAYELWGQPKTIQDLQIIFIKYLEGSIDALPWCDLGLSPETALIQEE
LIQLNERGFLTLASQPATNGSPSTNKIFGWGPAYGVVYQKAFIEMFVPKNIWENGNMKKA
IEQYGRAKLTYYANDSQGNFETNLESNSSNVVTWGVFSDSQVIQSTIVSEESFKAWSDEA
FSIWLEWAKLFPRNTSTNSLLRQIHQEYCLISIVHHDYINPDELWEIILS
>A0A5N9F4A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MKIKDILEKTRPVSFEFFPPRQADGIPAVLETLDELKVYSPDFVSVTYGAGGSTRAFTEE
ITFEAKRTAGVEVMAHLTCVGQTKEEIHGVLERLEAEGVENIIALRGDPPRGSTEFVPVE
GGFQHATDLLEHVKSNFKFGVAAACYPEGHTESVDLGSDLKYVKMKVENGADFLVTQLFY
DNRHYYDFVERARAGGIDVPIIPGVLPVLNSAQVRRFTALSGSEIPPELDKLLDKYADND
DSARDMGVEYATAQVRDLWDVGVPGVHFYVLNRSYSVSRILDNLTIPGHHRQD
>A0A4P5WCF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium|TrEMBL
MPTQNTPQFSFEFYPPRTSEGAVNLDTVQKQLSQLNPEFFSVTFGAGGSTRDKTFETVVG
IQKKGISAAPHLSCVASTKENIRSILNDYRENGISKIVALRGDLPSGMMLAGEFRYANEL
VQFIRAETGDFFNIHVAAYPEVHPQATNFNDDFKNFKRKVDTGANAAVTQYFYNAESYFH
FIEQCQKAGITIPITPGIMPITQYSQLFRFSEMCGADIPRWLRKRLESFGDNREAVKEFG
LEVVSKLCQQLLDGGAPSLHFYTMNQAAPTLAILKNLHY
>A0A4Y9QZQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia flava|TrEMBL
MAIELPPTDGATRLPVSFELYPPRTDAAAIALGRTIDRLTEVDPAFISVTFGAGGSTRDR
SLTVLSYILENTSVQPMAHLTCVGSSAAEANRLVRQFLDAGITSFLALRGDPPLDGTPLS
VGDLQSAAELVQLIHRVQQEREPFAQEAVRGTPGGTRLRARPRPERVAVAAFPNGHATSR
GPQQEIDALLAKQASGANLAITQLFYRADDYLAFVERARAGGVSIDILPGIMPASSAPRL
RRIAQLTEEDAPDELLIALEIEPTEEGRSEIATTFFSELAAEVIAEGAPGLHLYTHNKHT
PVLDVLERLDRLPRAAHGPIKENA
>A0A1B4FXR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia mayonis|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQQ
AGLEAAPHLSCVGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFVRKVKAGANAAITQYFYNADAYFRFVE
DAAKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKLVCERLGL
>A0A0S8HKD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. SM23_62_1|TrEMBL
MKVIDKILNTKETLFSFEILPPVKGTSIDQIYRTLDPLMEFKPMNINITYHQQEVIYRQV
NEKLLEKKIVRKRPGTVAISVAIKYKFNVLVVPHLICGGFTTEETEDALIDLHFLGMNNL
LVLRGDPPKGEKRFIPEEGGHAHAADLVRQIMNMNKGLYLEEGLENATPTDFSVGVAGYP
EKHFEAPNMKSDLHWLKEKVDAGADYIVTQMFFDNRKYFDFVRMCREEGIKVPIIPGIKP
ITYLNDVNLLPQTFYIDIPETLYHELEKCKSNSEARQVGVEWAVMQSKELKKSGIPVIHY
YTIGISDNIRQILEAVF
>A0A5C8HHJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lavendulae|TrEMBL
MGTALLDDFSLEMTGKDVPALEEAGGSIPRGTRINVTFLAGEDHAPRLAAARAVRRLGFV
PVPHISARRLPSRAALEEFLAGLAEDGTADDVFVVGGDPARPEGPYEDALAVIRSGLLER
HGVRHIGISGYPEGHPAISGPALWSALTDKAAAIGAGPFTGDVITQFGFDAEPVLDWLAA
VRARGIDLPVRIGVPGPAGVRRLVGYATRFGVGTSASVARKYGFSLTNLLGTAGPDRFLH
ALGERYDPARHGVVKVHFYTFGGLRTTAQWVGAFRERAR
>A0A657IVR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia kristinae|TrEMBL
MELVREVEREHRAHLGAGRLAVGVAAYPVRHPESPSALHDIEVLLAKERAGADFAITQVC
QDPQDYVRLRARAEQAGVGLPLVAGILPVTSLRRYERVCALAGLAVDERFAHRLETAESE
TQRRRVGVARAGSRPWPPWTPGAGLHLYTSTSIPRPWSCWRSWTCLAPP
>V6V2Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium ulcerans NCTC 12077|TrEMBL
MSASHIPAAYQRSITEVLKMPSPGRVPFSVEFMPPRDTAAEQRLWKAAEAFHDLGTAFVS
VTYGAGGSSRERTMRVAHKLSKHPLTTLVHLTLVEHTEAELVEILDDYAAHGLSNLLALR
GDPPGTNPMAEWVATPGGLEYASELIELTKKNPKTSHFHVGIASFPEGHYRAPTLEADTE
FTLQKLRAGAEFSITQMFFDIDHFLRLRDRLAKADPEHGCKPIIPGLMPITSIRSVRRQM
ELAGASLPRELEKQLLDAAKGDEESHKEDVREVGIELTTQMAEKLIAEGVPDIHFMTMNY
VRATQEVLHNLGMAPAWGTDYGHDAVR
>A0A7G7UK81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. PAMC28748|TrEMBL
MGFLEDIKNKTLIADGAMGTLLYSYGIDRCFEELNISKPEEIRRVHEAYVQAGADIIQTN
TYGANFIKLSRYGLEDETKQINEKAVRLARAAAGSAYVLGTLGGIRTFNKNSYSLEDIKR
SFREQLYLLLNEQPDGLLLETYYDLEEAREVLKIARKETELPIILNVSMHEEGVLQDGTP
LADGLKQLASLGADVVGINCRLGPYHMIRALEEVPLLEDAYLSVYPNSSLPSLVEGRLVY
ETDDEYFRESAEEFRNQGARIIGGCCGTTPNHIRAMAEAVKGLPPVTEKRVKIRKKAALA
VQNERTEPALDDLAKQKRSIIVELDPPKQLNFEKFLHAAEELKSAGIDALTLADNSLATP
RISNVACGALLKQRLDMRSLIHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRLE
KKIACGADYFISQPVYSEEQLIKIHEETRHLETPIYIGVMPLTSSRNAEFIHNEIPGIKL
PDSIREKMALAGNDKQKQAEEGLAIARSLLDAACDLFNGIYLITPFLRSDLTAELTAYIH
QKEKEKTNV
>A0A7M1KF37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas poae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVAAAPHLSCVGDSKADLRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLHNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A8E2A8V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliivibrio fischeri|TrEMBL
MAYSHASHLESLNQNIAELDGNINVSFEFFPPSSEKMEETLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLIAAPHLTCIDASRSELIDIVNDYWANGIKDIVALRGD
IPPGGGAPEMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQASRFAKMNNVKIPGWMAQQFE
GLDDDPVTRQMVGASHAIDMTRILSREGVKDFHFYTLNRAEHTYALCHTLGVRPK
>A0A847YL08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonellaceae bacterium|TrEMBL
MRICELFQSRKPVVSCEIFPPKHDYPVETIFDTLAALSELRPDYISVTYGAGGSSCARSV
QIASKVKNDYGVETLAHLTCVGADRRTTDEVLEQLQRENIENVLALRGDLPPEIPCGHGE
EYHEYAKDLIAHIRERHNFCIAAAAYPEGHPKCPSLAQDRERLKQKVTAGADFLITQLFF
DNRLFYDMLDQLAKIGIHCPVTVGVMPVLNAAQIRRMTELCGASIPNKLTDLLNRYGNSP
ADMEKAGIDYACAQIVDLVEHGVDGIHLYTMNKPRQTARILHETGLR
>Q0CE17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus terreus (strain NIH 2624 / FGSC A1156)|TrEMBL
MEKITDKIAALPPDSNYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRGLVDKALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRQQHGDYFCIGVAAYPEGHPADSFQDVQDPERDLPYL
VEKTQAGADFIMTQLTYDIDAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVKIPPQILSRLEEVRHDDDAVKRIGVDILKDLVDGMRDIPCPGLRGFHFYTLNLEKT
VSFILERCDLIPPYTEAGDEDALVDGGSLSALDSSSYVAPNGIPIRTLARRRSSINSLPH
NRVIVDREVSNESSKDSVSHEAPATSAGVPAMPPDRTTTLQISEGLGALGREATWDDFPN
GRWGDARSPAFGEIDGYGPSLHVTPSVAHRIWGYPVTRDDINTLFRRHVSGELHMVPWSE
GGAEEGSGGLNPETETIRPELLQLIDGKGWWTLASQPAVNGVRSDDPIFGWGPPREGFVF
QKPFVEFFCPTKDYQTALKPMLQKHGHEKLAWFATNANGDFESSLPAQTSDADPIEMNPN
NVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPRGSPTERFLEETKND
VWLVCVVGQDFGAGTEMGSKEEEDEKKFMWRELVNC
>A0A2G9XHW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacteraceae bacterium CG23_combo_of_CG06-09_8_20_14_all_50_8|TrEMBL
MKTNSRIEKIWESGGFIVTSECGPPRGADGDVIRRKGELLKGVVDGVNVTDNQTSVVRMS
SLSACVILKGMGLEPILQMVCRDRNRIALQSDILGAAALGINNILCLSGDHQKFGDHPQG
KNVFDIDSVQLIQTVCRMRDEGRFLGGEEVKGKPLLFVGAAENPFADPFEIRAMRLGKKV
KAGCQFIQTQCIYNVEKFSRWMGMVCDRGLHEKCAILAGVTPMKSVGMARYMKNNVPGMD
VPDDMIERMKGTPKEKQAEEGIKICVETIERLKEITGVRGIHIMAIEWEEKVAEIVKAAG
LLPRPEV
>A0A1J5CBS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium CG2_30_57_122|TrEMBL
MSPTRFPISIEFFPPKTPEGVEKLRVARQQLYALKPEFCSVTFGAGGSTQEGTFSTVSAI
LAEGVPAASHFSCIGATHARVREQLATLKAMGVKRLVALRGDLPSGYGTGGEFHYASDLV
AFIRAEMPDDFHIEVAAYPEMHPQAKSPESDVKAFAAKVQAGANSAITQYFYNPDAYFRF
IEEADALGVRVPVVPGIMPIASSSQLMRFSDACGAEIPRWIRLRLQSFGDDTASIKAFGL
DVVTDLCEQLRAGGAPGLHFYSMNQSAATLEICKRLGV
>A0A3C0X6L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MSMENGARARAFLDACSWEVSAKAVQALRAEAARIAPGSTISIPYLASEDDEARLAAARA
IRELGFQPMPHLSARRIGTQAALERFIQRAVSEAGVERCLLIAGDLAAPAGPFADSTAII
ETGLLERAGIKVVAVGGHPETHPVMTAAQRWQVLENKCQRIEARGMAPWIITQFAFDAEI
VLAWLKALRARGIAHPVLVGIPGPASVTRLVRYAAMCGVGASTAMLARYGISLGRLLGSA
GPDRFVDKLLAGLGDELGPVSPHLFPFGGIAPSLDWVQQYRRNARSG
>A0A453M7X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aegilops tauschii subsp. strangulata|TrEMBL
IQEAAANGRTVFSFEYFPPKTEEGVENLFERMDRMVAHGPNFCDITWGAGGSTADVTLDI
ANRMQNMVCVETMMHLTCTNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDKFVQVAG
GFSCALDLVEHIKAKYGDYFGITVAGYPEAHPEVILGEEGATEEAYSKDLAYLKRKVDAG
ADVIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTKIPAEIT
AALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNLGLIEES
KLSRTLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWGDSRNPSYGALN
DHQFTRPRGRGKKLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPETTIIDD
QLVKINSKGFLTINSQPAVNAEKSESPSVGWGGPGG
>A0A1M7V0N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus obscurus|TrEMBL
MSVERPGGTRAPTRAGPPPPADQPPTRRSARTALERALRAASYEVLPLRGAEESVVEHVP
RAVPLTVTVTEAKGLAPTLELAERLAGHGFTATPHLAARLVRDPAHLADVVARLRAAGVS
GVFVVGGDAAEPAGTFPDALSLLEALQTTGSHFETVGIGGYPEGHGHIDPELIERALERK
APHATHVITQLCFSAATTAAWARQVRLRGVDLPIRVGLPGAVTRQKLVRISAGLGLGQSA
RFLAKQQSMFWRFFLPHGYRPDRLVDGLAPTLDRPEHHLQGFHFFTFNEVARTEAWRREW
LARLSDTGTQ
>A0A4U1CBQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter cryotolerans|TrEMBL
MKITEHIKNANGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QDNGLLQKVAYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADNSFIPTKGGHCYATDLIAHIKNHNDGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNADFKFLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPDDLVDDLSQAKSNAEAKEIGTAAMIKQCNELIEFGAPVLHF
YTMGKPAQTKEIARAIF
>A0A3D5JNV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTASKLKAFAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASELISFI
RAEHGDAFRIEVGAYPETHPQANDALLDLKHFKTKIDAGADAAITQYFFNADAYFHFVDA
VRKLGVSVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDAESVRAFGAEVV
AGLCERLVAGGAPGLHFYTLNLARPTTQVLKLLRG
>A0A3N4UD60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tibeticola sediminis|TrEMBL
MNALPISFEFFPPKTPEGAEKLRVVRRALYAWAPEFCSVTYGAGGSTHEGSFATVREILA
EGVPAAAHFSCVGATRERVRAQLAELHAMGVRRLVALRGDLPSGYGLGGEFQYASDLVAF
IRAETGRAFHIEVAAYPEMHPQARSPEADVQAFATKVRAGADSAITQYFYNADAYFRFRD
EVHALGLDVPIVPGIMPITSATQLLRFSDACGAEVPRWVRLRLQSFGDDVESIKAFGLDV
VAALCERLRAGGAPGLHFYTMNQSAATIEILRRLGLGRAAVDG
>A0A1T1DI20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira kirschneri serovar Pomona|TrEMBL
MKKVSEIYGSTKGPVYSFEFFPPKTPEGDLKLMETVKELSLLNPDFITVTYGAGGSTRDK
TAQILSRISKNYSFPTVSHFTCVGSDKGQILETLKGIRSSGIVNLMALRGDPPKGEGEFK
KVENGFENATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVRNLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQIPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A177WGA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Batrachochytrium dendrobatidis (strain JEL423)|TrEMBL
MKVVDKIQKANDEGRCFWSFEYFPPKTESGVVNLFDRMERMYLLGPEFIDVTWGAGGTTS
DLTLEICTTAQAVFGLETCMHLTCTNMPRIKIDEALEQAKNAGIMNILALRGDAPRGQTN
WTKVETGFSYATDLVRYIREKYGDYFCIGVAGYPEGHTETPDKEADLLYLKEKVLAGADY
IVTQLFYDVDIYIDWSKKVRAMDITIPILPGLLPIQNYSGFKRMTALSKTFVPQFILDDL
EPIKDDDQAVKDYGIRLAVQMCNKMREAGQRGFHFYCLNLERSTRLILEGLDFVAPRENV
KPLPWNPSLGKNREKETVRPIFWRNRTKSYIMRTDGWDEFPNGRWGDSRSPAYGDIDGYG
IRLKYSAEDCLTFWNHPETLGDIYGLFEKYCMGDLSCLPWSDTPLFPESEILRARLANIN
RSGFLTINSQPAVDGALSSDSVYGWGPKNGYVYQKAYLEFFISPKKLDLLLEKLCQHPFL
TYHAVNKNGDLKTNTKNDSPNAVTWGVFPGQEIVQPTVVEGVSFIAWKDEAFELWKQWSQ
LYSAESPSYKIINHVTSNWFLINIVDNNYKNRFAIYDILDQVAADAKDIIDH
>A0A809NZ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHADHPVYILGTIGGLAGDTDATVQR
ATPATIAASVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPIYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFIGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A6N6LNF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. LR185c|TrEMBL
MSAEFSFSYEIFPPRREDNISNLTQIFDDLSILKPNFISVTFGAGGSINSKHTLEVANLI
QNEYKIPSIVHLPCIHSSKERVSQILKECQRLGIKNILALRGDVCEGQEKSRDFSYASDL
VKFIKTQGDFEIYAAAYPEKHNEAKDFVQDIHNLKIKIDAGVNKLITQMFFDNEDFYKFK
EHCEIAGIKVPILTGIMPITNKRQVTKIASLCGAKIPLKFQKILDKYENNPLALEEAGIA
YAIDQIVDLIASGVSGIHLYTMNKSKAAIKIYNTVKYMLDK
>A0A8J6TZ06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Taishania pollutisoli|TrEMBL
MKVTEHIAQAKETLFSFEILPPLKGKSIQSIYDGIDPLMEFKPKYVNVTYHREEYIYKEH
DNGLLEKISVRKRPGTVGICAAIMNKYHVDAVPHLICGGFSKEETENALIDLQFLGIDNV
LALRGDSIKTEAAFRPHKNGHAYAVELIHQVRDMNNGVYLMDDIHLESTDFCIGAAGYPE
KHFEAMNLSTDLEYLKQKVDAGAEYIVTQMFFDNSKYFRFVEACRSVGINVPIVPGIKPI
KTLNHISFLPKFFHIDYPEELSRELLKCKTNQDAEKLGIEWGIHQSKELKEKGVPCIHYY
TMSNSSSVKAIAKEIF
>A0A1Q8RHP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. 'caviae'|TrEMBL
MSKLLDKLKTDILVADGAMGTLLYADGLESCHDYYNISHPERILAIHQAYIEAGADVIET
NTYGAKRHRLKSFGYDNDVKQINQKAVEIARQAAGENVFVLGTIGASRGLRQCELSLEEI
VDETLEQAQALLETGQLDGLLFETYYDREELEAVLKAVRPLTDLPIITNMALHEAGITED
GRPLVEALSNLVMLGADIVGLNCHLGPYHMIQSLKQVPLFAQSYLSAYPNASLLSFVSDD
EKGQYRFSQNADYFEYCARLFVEEGVRLIGGCCGTTPDHIRAIKRGIQNLKPVERKVITP
LITEQEFIDEISKKETLADKAKKEVTIIAEIDPPKTLAIDKFVEGIRALDKKNIAAITLA
DNSLAKTRICNLSLASLLKDEVTTPFLLHLSCRDHNMIGLQSRLLGMDVLGFDQILAITG
DPSKIGDFPGATSVYDATSFKLLSLIKQLNQGKGYSGASLKRATHFTAAAAFNPNVRQLE
KSSRLIERKIKAGADYFITQPVFNQETIHQLGELTKAYDQPFFIGIMPITSYNNAVFLHN
EVPGIHLSETLLEKLEAVKDDRAACQAAALAESKALIDCALNYFKGIYLITPFLRYDLTL
ELIDYIQERTAVVKKRA
>A0A7U3UQD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SN-593|TrEMBL
MALGTSSTRTDRATTIRELLASGHRSYSFEFAAPRTEKGERTLWNAIRRIEAVRPTFVSV
TYGAGGSSREGTVRATDRIVSDTTLTPCAHLTAVNHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPMGEWVAHPQGLTYAAELVRLVKESGDFCVGVAAFTEMHPRSTDPAEDTRHFLD
KCRAGADFAITQMFFDPDAYLRLRDRVDRAGCTVPIIPEVMPVTNVRQIERFSQLGNAPF
PPDLAERLLAVQDDPAAVRAIGIEFTTEMCRRLLAEDIPGLHFITLNHSTASLEIYENLG
LHQQAA
>R7YW82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coniosporium apollinis (strain CBS 100218)|TrEMBL
MHISEKLAEAQKAGKPSYSFEFFPPKTAQGVQNLYDRMDRMHGFGPSFIDVTWGAGGRHS
QLTCEMVKTAQSAYGLETCMHLTCTDMDKSKIDDALREAYNAGCTNILALRGDPPREREK
WEAKAGGFRYAKDLVKYIKEKYGNHFDIGVAGYSEGCEDQEDADLLIDHLKEKVDAGGTF
VITQMFYDVDIFLDWVKKCRAKGITVPIIPGIMPIHTYAAFLRRAHWTKCHVPEEWTKAL
EPVKNDDAEVREVGKDLVAKMCRRLLDAGIIHLHFYTMNLAQATRMVLEELGITPDLESP
LDKPLPWRQSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNVKLWGQPRSVKDIANLFVRYMQGKLESLPWSEAPISSEADVIKDNLID
LNQRGLLTINSQPAVDGAKSSDPVYGWGPRNGYVYQKAYLEVLVSPEVIAELITRIERNP
DLTYYAVNKQGDLKTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEFFRLGHDW
ASCYSAANPSRYVIRDLMDNWYLVNIVHNDFHERHGIFPLFEGLEIKDMEKPLHVNGEVA
TNGDAPESKPATNGDRTAEPKPSTNGTKEEEKPAVDDGTEGWAKPAKKSNAPLPQTFPVP
P
>A0A5E7ZRW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Imperialibacter sp. EC-SDR9|TrEMBL
MKVVDHINNAKKTLFSFEILPPLKGQSMQAIIDTIEPLMEFKPPFVDVTYHREEYMYKKR
QDGLLEKVTIRKRPGTVGICAAIINRFKIDAVPHIICGGFSKDETEDALIDLDFLGIDNV
LVLRGDPIKSEGAFVADPNGHKYASELLAQVINMNNGRYLHEETEGNHTNFCIGVAGYPE
KHFEAPNLSTDIRHLKRKVEMGAQYIVTQMFFDNNEFFAFEKKCREEGITVPIIPGLKPI
TSVRQMTALPRSFFINLPNDLVNELEKCKDNKAAKTVGIEWCINQSKELMAGGVPVLHYY
TMSRAESVKDIASALF
>A0A1H3R020|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus africanus|TrEMBL
MSLEVPDATRAPMGTGPPPADRRPAWRRSRGALERALRDASYEVLPLRGAEASVVEHVPR
TVPLSVTVTEAKGLTPTLELAERLSRHGFTVTPHIAARLVHDASHLADVVARLHAAHVDS
VFVVGGDAAEPAGAFPDALGLLEALETVGHRFRHVGIGGYPEGHGHISPELIERALERKA
PHATHVITQLCFHPATTTAWARQVRQRGVDLPIRVGLPGAVTRQKLVRISAGLGLGQSAR
FLLKQHSMFWRFFLPHGYRPDRLVDGLAPTLGRPEHHLQGFHFFTFNEVARTEAWRQEWL
ARLSDAGTG
>A0A554VVY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. KBS0703|TrEMBL
MSPPSLIDTHPNLSETAPVALSYELFPPRSPAAAETLWTTIRELETTDPDYVSVTYGASG
SNRDTAVELINRLVLETTLRPLAHLTCVGNTPSELAEIIGELLDAGVRGILALRGDQPKD
SGEPVSGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFRTEQYADLITRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAPELIERLAAADSDADRLRIGVSATVDLANAALDAGAPGLHLYTFNEHQSALEVLDKLS
LVRPARSASRLNAIARRQLAS
>A0A1X6YIH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria meonggei|TrEMBL
MTKPDISFEFFPPKTLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLPVAAHLTCVDASRQETLEIADAFARAGVQDIVALRGDPPAGQDRFEPHPDGFANSV
ELISALAETEMFSIRVGAYPDIHPEAQNARTDVDWLKAKLDAGADEALTQFFFEAETFFR
FRDACAKAGIDKPIVPGILPIENWKGARNFANRCGTRIPAWVDQAFEKAIRDDREDLLAT
ALCTELCSDLIEGGVDKLHFYTLNRPELTRDVCFALGITPKTELQNVA
>A0A519L7C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
LRMLLRIDAGGFDITVGVYPEKHPESPSLDHDIDVLKAKVDAGATRAVSQFFFDIDAFLR
FRDRVRAAGVTIPLIPGIMPVSNFAGLARMCGACGASIPDWLRAHFEGLDDDPETRKLLA
ASVAAETCARLQEEGFSDFHFYTLNRADLVYAICRVLGVRETAQ
>A0A3E2D6I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium N170|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNAAGVFNHASDL
VSYIRSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A519HIM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MAALSLSEARALLLSPLGPVARAGQDASRPRVSFEFFPPKTDEAEANLWKAVQRLAPLNP
AFVSVTYGAGGSTRERTHRTVSRILAETDLKPAAHLTCVEASRDEVDEVIREYKALGVNH
IVALRGDPPGGAGIGGVYQPRADGYANATELAQAISRVGGFDITVGVYPERHPESPSIDH
DIEVLKAKIDAGATRAVSQFFFDMDAFLRFRDRVRAAGVTIPLIPGIMPVSNFTGLQRMC
GACGASIPEWLKAHFDGLDNDPETRKLLAASVAAETCARLQEEGFQDFHFYTLNRADLVY
AICRVLGVREQATA
>A0A0A0EYW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter daejeonensis GH1-9|TrEMBL
MSFPISFEFYPPKTDEQRAQLDKTAAKLKAQSPDYVSVTFGAGGSTLSHTPEAIQHLRGR
HGYDAAPHITCMGGSREEIRGLLKLYKALGARRLVTLRGDLPSGMVSPGDLRYASELVEF
IRNETGDHFHIEVAAYPETHPQARDAHADIKAFVTKVKAGANGAITQYFYNADAYFRFVD
DARKAGVDVPIVPGIMPISNFSQIRRFSELCGAEIPRWVAQRMQAYADDVDSVREFGAEV
VAQLCRRLVDGGAPGLHFYTLNLSKPTLNVLARIGAV
>A0A7C7KJY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiloniellaceae bacterium|TrEMBL
MADARHILRPTGTGAGQTPRPRFSFEFFPAASPLAEERFWRALRDLEAFDPGYVSITYGA
GGTTQERTIRAVERVLNETDVVPAAHLTCVGASRAEIDALAERYWAAGVRRIVALRGDPP
KDSRDFRPHPQGYAYAADLVAGLRRVADFDISVAAYPEVHPEALSAQADLDNLKRKLDAG
AQRAITQFFLDPDDYLRFLDRARAAGITAPIIPGILPIVNFQRTVQIAKDCKAAVPAWLV
RLFEGLEENADVRNPVAVSVAAELCRYLVLHGVEEFHIYTLNRADLTAAVCRLLLSDAAG
RDEVEAARPLAVGGLR
>A0A7X9WPH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. G-3-2-10|TrEMBL
MSNKVDPYAAPLFADVAGDIDVSFEFFPPKTEKMEETLWESIQTLSPLGPRFVSVTYGAG
GTTRERTHNTVARIARETSIPAAAHLTCVEATREEIDQVANEYWEAGVRHIVALRGDPPR
AGEKYSTHPGGYENAADLVAGLRKLHPFEISVAAYPECHPDSPHAAADLDNLKAKIDAGA
NRAITQFFFEPETFFRFRDDAAKAGITAEIVPGIMPVMSFAAVTKMSAMCGTDVPKWMGK
LFEGLDDHPAARQLVAATVAAELCRKLYAGGERAFHFYTLNRAELSYAICHLLGVRPKVL
EPVAA
>A0A857I445|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter gyllenbergii|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKTVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A8H2ZP92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sclerotinia trifoliorum|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILTLRGDPPRSEE
YRAVDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDTFEQRLRDHPSGAFKTIPIIPGMMPIQSYQMI
KRTTKLSHAKLPTNIIRRLDEVRGDDEMVKKVGVDILSEMVEHLKSTKSQHSGPRGFHFY
TLNLEKAVSFILERTELIPDAETVAALEPEYVSTIPDIADLLSIHSGSHRRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATALEAGVPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITNIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGVKSSDSIFGWGPKNGFVFQKAFVELFL
PTSDWETLHAKLTSPALRDTVSFYASNAKGDFISSDEAVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSETRMIIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLN
>U4DWE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio nigripulchritudo FTn2|TrEMBL
MSYTHASHIDALNQNVAELSDDINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASRDELVNIANDYWNNGIESIVALRGD
IPPGGGAPDMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAINNVKVPGWMSKQFE
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQG
>R5V6K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:18|TrEMBL
MKVSEILKKNEVTISCEIFPPKQGAQLQNYKAIAAEIAKLKPAYISCTYGATGGTSDYTV
EIADAINSYGVPAIAHLTCVSSTREKVHTVIHELKERGIENILALRGDIPTNTDFPLPDQ
YHHAIELIREIKEAGDFCIGGACYPEGHPEAANMNEDLDHLKEKVDAGCEYLTTQMFFDN
NIYYRFLYKALAKGIDVPVTAGIMPVTNAAQVKRTISLTGNLVPAKFLSIVDRFGDNPAA
MKQAGIAYATEQIIDLIANGVNHIHIYSMNKPDVAAAIMNNLSQIYVREQA
>A0A2E9YUD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseobacter sp|TrEMBL
MTTPAVSFEVFPPKSVDASFRLWDTAQALAPLGPRFFSVTYGAGGSTRDLTHDSAHVLRR
TSGLPVAAHLTCVGASKAETLEVANSFAEIGVTDIVALRGDPENGASVFTPHPDGFADSC
ELIEALAATGKFTLRVGAYPEPHPESPDQAQNVEWLKRKFDAGADEAITQFFFETETFLR
FRDACAAAGITKPITPGIMPVTNWKSARNFATRCGALVPAWLDEAYNAALRDDRHDLLST
ALCSEMCSELVDEGVENLHFYTLNRPELTRSVCRALGVTSQTALSDVA
>A0A2T3BYK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter woluwensis|TrEMBL
MSPPSLIDRPLQQQGTTPVALSYELFPPRSQAAEEVLWATIRELETTAPDYVSVTYGASG
SNHDTALDLVARLQEETLLRPLAHLTCVGNTAAELAGIVAQLLDHGVRGILALRGDLPRD
GAPLPEGSLHYAQDLVELIRRVEQSRSALLCAGKVAIGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHARQYEDLLVRARRAGVTIPIIPGVMPLTSLRRVTRLSELSGVA
PDPALMHALETAGSELEAQRIGVAATVELANAALDSGAPGLHLYTFNEHRHALDVLDRLN
LPRPSRPLHERAALAS
>A0A1S1FU01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus sp. HMSC61B11|TrEMBL
MSYANEINTLNQHLADTNKKINVSFEFFPPKNEKMESMLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGIEAAPHLTGIDATPEELKEIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIEAEIVPGILPVTNFKQLQKMASFTNVKIPAWLAKAYEGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHTLGIRPTTNP
>A0A411E6Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muriicola soli|TrEMBL
MKVTEHIKRAKGNTLFSFEIIPPVKGRSIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLFDKKLTRMRPGTVGICASIKHKYDVDTIPHVLCGGFTREETEYLLVDCHYLGIDNV
MALRGDALKEEQYFEPTKGGHQYASDLVVQIKNLNKGQYLHEVIETDNCSDFCIGVAGYP
EKHMEAPSMKTDLKWLKKKVDLGAEYIVTQMFFDNQKYFDFVKAAREAGINVPIIPGIKP
IAIKRHLQLLPQVFRIDLPQELIEEVEKCSSNKEVRKVGIEWTIYQSKELKKAGAPVLHY
YSMGKSDNIREIAKAIF
>A0A3A9G057|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium 1XD42-8|TrEMBL
MDVSTVFKKRMSFSFEVFPPKMDQPMEPLLETLDHLYTFDPDFISCTYGAGGTNKGRNSE
ICASIKKSGKAEPVTHFTCVGNSREDVKQIMQEYLDLGITNVLALRGDLPAGWEGTRGDF
AHADQLIGFIHKEFPQLNIACGACPEKHPDAPSMEQDIMHLRAKQDNGATFIMTQLCHDV
DAFSRFMERIRKAGVTLPVDMGLMPVLRKDPIIRMTLSNGCSIPGELATIIGKYGDNPED
FAKAGKEYTVRQIARFIDAGIDGLHIYTLNKYADVAEILGMAGIQGSPVK
>A0A1F4I9G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFCSPHIGHO2_12_FULL_69_20|TrEMBL
MLTTDQRRATPISIEFFPPNTPVGSEKLKTVVQELSVLQPEFFSVTYGAGGATREKTLAT
VRDIAALGFEAAPHLSCVGSTREGIAEILATYRAQGIHRIVALRGDLPSGTAVAGEFRYA
SELVRFIRETQGPDWHIEVAAYPEYHPEQRYARKDLQHFADKVACGANSAITQFFFNPDA
YFHFVDEARRLGVDVPIVPGVMPIHNFARIVQFAGRDGIEIPRWVMLKMEGYLDDAASIR
AFGIDVVAQLCQRLIDGGAPAIHFYALNQSALTLAICQRLKR
>A0A7L2JR28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cinclus mexicanus|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVMALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A329TZ20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MLDVRKLLAQRPLLFDGGMGTYYKAKPGQECEQANLTDSDGILAVHRAYLAAGADAIKTN
TFSLPRLAAAQQPGWEQLADAGWQLAAKAAGETGAAVFADLGPAPDTENLPAEQVYLAVA
KRFALLGARNFLFETLSAEEGVLEAIRALKQTVPEAFVLVSFAVLPDGYTREGRYCAELV
RRMVQSGVVDAVGLNCVSAPGAMRALVQQLGDAGLPLSVMPNAGYPVVARAQVRYQGKPA
YFARELSRLAAEGVRILGGCCGTTPQHIAALRTALDALPEALPAAPAAKPAATVKPAVET
DDVFLRKLRAGQRVIAVELDSPKDADLTAYLEGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGMNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPITVFGALNLNARNFEVELRRAAEKLENGMSGFL
TQPVLSAQAVENLKKTRETLGERAKILAGILPVVSQRNAIFMENEVNGIHVDEVIIQKFE
GLDRTAGEELGLEVSVQAAKAAAPYADGFYLMTPFNRVALMERLIARLRTEVTD
>A0A521TI17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosarchaeum sp|TrEMBL
MAVIYEINPPKIPDVKTSNEEINSLLAKLVQRVSDISTLCDGIHVTDSVLGTRRVSALTT
GKMLKTNHPNLQITISMRVRDKDMDSIKQIVQESIDLKLDGILVLKGDPSKENPTDSGLS
PSHVVKQLNELGYGKKMNFFLSLPSNPNFEKIQKKITAAPKGFMTQVIHSTEQVQRISNK
LRASGFRIIPCVLLPTEKNENSAKFLELDWSGYKENP
>A0A1Y0IIG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tumebacillus avium|TrEMBL
MPKKRRFLLYSDFIPLSEHYYIEALRQREGGCSVSSRHELFRQKLGTDVLIGDGAMATWL
YQQGHAVGSSTEELCLKNQEWVREAHMAYLRAGAQVIETNSYAANREALARYGLERKTTR
INRAAVQLARQAVEIAEADAFVVGSIGSIAAARVMTANVEEFRDSFEEQAVALLHEGVDG
LVLETFFDLEELLLALDVVRPLVASSGVPIIAQCSLLDVERTRDGYLLSDAYFKLKEAGA
DMVGLNCRLGPAEILRALERAVVPEGLGLSAFPNAGRPAIVDGEFAYKPNYQYFGDSAVK
LWEQGVSLIGGCCGTTPEHIQAIAGAVSGLKRRPRVNPENAPRIEVFEREVVRFQQSEMP
TIVDLVEKRHTIIVEFDSPRDLDVERYVEGSHELYKAGADAITIADNSLATTRMSNMALG
SIIKRELGIEPVVHVACRDRNLIGQQSHLMGLHALGINQILVITGDPARVGDLPGASTVF
DLTSFDLIRMVKQLNQGVAFSGRPMKNQARFVCGAAFNPHVRNLDAAVARLERKVEAGAD
YIMTQPVYDLETMLAIKEATAHIKVPIFIGIMPLTSTRNAEFLHNEVPGIKISQKSRERI
KRFEGAAARAEGVEMCKELLDEAVKHYNGIYLITPFNYFEMTVELTKHVREITQVTSRAS
TF
>A0A6I5YVZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. CAP-1|TrEMBL
MTMPMLQNDYHLSPSRLSDHYSLEITAKDVDALHDSKALIAPDTQIAITFLPGEDPSSRL
AATQAVRKLGFEPMPHFSARRIDSLRSFETYLHAAVAQAGVTRCFVVAGDPLLPEGPFSD
SAALIATGAFERAGIRTLGVGGHPEGHPHMSEAQCWDVLQSKCAEIAGRGMEPLIVTQFG
FNADPFVSWLDNLRRWGIDAPVRIGIPGPAGIKTLLRFAGRCGVGASTAVMAKYGISITR
LIGTAGPERLIDDLAARILPSHGDVRLHFYPFGGIERTVRWIENHRAPR
>A0A3Q9V7E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Riemerella anatipestifer|TrEMBL
MKVTEHIKKSEGKTLFSFEILPPLKGQNIQCIFDAIDPLIEFNPSFIDVTYHREEYEYVE
VRDGLLEKRVVRKRPGTVGICAAIQNKYKVDAIPHILCGGFNREDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKNGHTYASDLVKQIQNMNKGIYLDTSLEKAAPTNFSVGVAGY
PEKHMEAASFSQDIGHLKKKVEAGADYIVTQMFFDNQKYFDFVDRCRSEGIEVPIIPGLK
PIATKSQLSLIPHRFKVDLPDDLVTAITKANNNNEAKEIGVEWCIEQSKDLMKKGVPILH
YYSMGKSESVRKIAEAIF
>A0A3C0HBZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospirales bacterium|TrEMBL
MKIIEHFEKSKGKTLVSFEVLPPLKGGSMQAIFDALDPLMEFNPPFIDVTYHREEFLYNK
RESGYYEKVAIRKRPGTVGICASIMHRYGVDAIPHLICGGFSKEETENALIDLAFLGIDN
VLALRGDARKFETKFVPHPEGNRYAVDLVNQTKDMNDGVYLDCNIENGAKTNFCIGVAGY
PEKHFESPNLNLDLKYLKAKVDAGASYIVTQMFFDNQKYFEFVDACRAVGINVPIVPGIK
PVTKKYQLNSIPRNFFINMPDDLVASVSKADTAEKIQQAGIEWCVHQSKELKKAGVPCLH
YYTMGDTDIIKKIIQSI
>A0A2G9FR65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hodgkinia cicadicola|TrEMBL
MSSLSKLLTSDLNLHQTKLLEFNSVTCSSSNKNRFNSATISTTILERSHNLSIVLHNILT
QTKYTLVPDIMPWHDLGINNMLLISGDKYVYNRKRDDSSNSYIIKMVLREGNVFNIGASY
PDSHVLCSSSFQDLFIVLLNRKGGCSAYITQIFNHMDNLLRNNLRCSILKLGSLLPGLFI
SSKHPLAVDINLKCGIYLTRQAKELLECGWLDGRATFLLYIYRTIEIVENNTTWIQIFTL
NKTRPIKVIIWILNDLVYYMKYWRIKNYTDCYKTISNRHNAYNKLLYKYIQH
>A0A1M7LY58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWB7|TrEMBL
MKIIDILKQDKMSLSFEVFPPKKETSFENVKAATEAIAKLNPAFMSVTYGAGGGVSQYTL
EIAKNLKYNFNIPMLAHLTCISSTKETIHQRIEDMKAAGIKNVMALRGDLTPELIANGRG
DCDYHHAVELIRELKATDADFCIGAACYPEKHPESANQAEDIKHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPDAMKQAGIIYATDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFAG
>A0A1V1VE95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium damsela subsp. piscicida|TrEMBL
MNVLNPIAVHYLMTTSLTWKLTMQPITNYQALSLQDSELRVRYNDVTRGVYFIGTTPPKT
STELSDVDGIADKLVDRIKDLAFDGLIVYDIQDEGSRISKPRPFPFKSTHDPRYYSSLLN
KKTGRPVITYKSVVQSEPEVFNQWLNEAWDQYQVRDIVLVGSPSTQNQVSLPLHEAYKTI
ADNEHPFFTGGIMIAERHAKKGNEHQRLIEKYQQGCNFFISQAIYDTQATIDLLTRYAIE
CQEKGLKPQRIILTFSPCGSAKTLEFIEWLGVSVPEATSLRILNADNPLHESIKMCCNSL
NQILEAVVEYDLPLGLNIESLTNRKEEIEGSILLYKLLRSTMDMYLAQHEFRKQQGLKKP
F
>A0A385ZT08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseorubiginosus|TrEMBL
MLATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVKETEQ
IVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWLAHPQGL
TYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDTDVSHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVDAAGCPTPVIPEIMPVTSVRMLERLPQLSNAIIPSALKERILTAQDDPTAV
RSIGIEFATEFCARLLSEGVPGLHFITLNNSTASLEIYENLGLHHRPQA
>A0A1D8P7Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Urechidicola croceus|TrEMBL
MKVTEHIKNAQGKTLFSFEIVPPVKGQNIQNLYDNIDPLMEFKPPFIDVTTSREEFVYVE
KGAGLLERKVTRMRPGTVGICASLKHKYNVDTVPHLLCGGFTKEETEYVLIDCHYLGLDN
VMALRGDSMKHESYFKPVEGGNKYASDLVSQIQNLNRGQYLHEKIDSEFPADFCIGVAGY
PEKHLEAPSMSTDLQRLKEKVDAGADYVVTQMFFDNQKYFEFVKAAREIGINVPILPGIK
PIAVNRHLNILPQVFRIDLPEPLINEVEKCKDNKQVRQVGVEWAIEQSKELIAAGVPVVH
YYSMGKSSNIKAIAKEVF
>A0A840WII7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis metallicus|TrEMBL
MLAAPTRPVAPRTPASRPRHIRDLLDSGEPMFSFEFFPPRNARSQERLWRAIREIEALGP
SFVSVTYGAGGGTRDLTVETTERIATDTTLMPVAHMTLVDHSVAELRHLIGRLADAGVSN
MLAVRGDPPGDPDGEWVRHPEGLTYAEDLVRLLKESGDFSVGVAAFPYKHPRSADVETDT
DHFVRKCEAGADYAITQMFFDPEDYLRLRDRVAARGCEVPIIPEVFPVVKMASIPRSEKL
SGAPFPRDLAARFERLGDDEKAVRAFGIEHAQRMCERLLSEGAPGIHFITFNQSTATREI
YREVAGHRVRRAAAERP
>A0A356M4L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MRPARDILTSDLILTDGAMGTYYAQQNANSPDSCERANLTHPERIRNIHREYLAAGARLL
RTNTFAAAQVGSDDPDQLRSIIRAGYNLAAECAGDLAYVAADFGPAYNLDTQESLSVNQI
ILDEFLSLSAELFIFETFADPAEFLPLCSLIRERAPQALVIASFTLSSDGYTRKGLPLAE
LSRVMEESPLIDLWGLNCGIGPTHLASQVRHLQAQGKPLSLMPNSGYPRWENQRLVFGSS
PDYFAQASLDLAGARTRLLGGCCGTTPQHIRALGRLLGQNPVRPAVVPVETPAVHPGKIR
REQDSFTVRLARRDFVLVCEYDPPRTSQVEPTINAVRQLQQAGVDALTLADSPLAKVRMD
PVSCAARIHRETGLPVLPHLCCRDRNVNALRSSLLAAHSEGIRRVLAITGDAIPESDRGF
VKPVFNLNSLGLLQLIQQMNQEFFADDPLSAAAALDPGVPNPGAELARVLRKQELGASLI
LTQPVYDDTGLDLIRRVRAAGLPVLVGLMPLVSYRNARFLSQEVPGIRMPAAILERFRPD
QAPAEAIAAGIAIANEIAALYRQDADGFFLITPFGRTDIMIRLIESLRRSNLLEPALPKD
PK
>D9PIX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|sediment metagenome|TrEMBL
AKKVAAGAEFIQTQCIYNMERFEKWMAMSRDRGLTEKICILGGVTPLKSAGMARYIKKKV
AGMDVPDEVVKRMEGVPAKEQAEEGIKICVETIQRLKEIPGVRGVHIMAIEWEDKVAEIA
ERAGLLPRPK
>A0A316PW27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MLIRQNFAKKSCVLSIEVFPPKTEPGWAKLQNTLRQFKAMEPAFVSVTCSAGGSGTEGIP
TADVAAFLKNELQIEPLAHVTCLGNTREELQANLEHLFALGVRNIMCLRGDRNPDLPQYD
DFLHASDMAAYIQKNFGCFGLSGGCYPEHHPESASLQEDVANLKLKQDAGVSHLVSQLFF
DNAFYYRFANLARKTGVTAPISIGIMPIAKKVHIQNVVNLSGATVPADFAALLAKWQDDP
DGLFKAGTDYAIQQARDLIEGGADGIHLYAMNNADVTQRMYDGIKDLL
>A0A515L938|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altererythrobacter sp. TH136|TrEMBL
MNEEIAHSAPLYASLPGDIGVSFEFFPPKTVKMAETLWESVRTLEPLRPDFVSVTYGAGG
STRERTHAAVQRIIRETAIPAAAHLTCVDATREEVDAIAREYWDSGIRHIVALRGDSSDP
AGGYRPHPGGYENAAALIEGLLKIAPFEISTAAYPETHPDSVDEQADLDNLKRKLDAGAT
RAITQFFFEPECFFRFRDKAAAAGITAEIIPGIMPIMSFASVQRMSGLCGTAIPGWLETL
FRGLDERPAARQLVAATVAAELCRRLYAGDVRQFHFYTLNRAELSYAICHLLGRRPAGDA
A
>A0A258GXJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium 32-64-14|TrEMBL
MSRTPSVSFEFFPPKTPDMEAKLWDSVKRLEPLNPSYVSVTYGAGGSTRERTHGIVKRMA
EETALKPAGHITCVAATKGEIDQVLRDYWYAGVKRVVALRGDPTAGIGARYEPHPGGYAF
ASDLIAGARRIADFDISVGCYPEVHPDAPSLKAEIDNLKRKFDAGATRAITQFFFYPDVF
FKFLDQARAAGITQPIVPGIMLQSNFKGLQRMATLCNTAIPARIAELYEGLDNDAETRDL
VTAHVAADLCQRLAEQGVDHFHFYTMNRAGLSLSTCRLLGIKAETLPS
>R6D5P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides coprocola CAG:162|TrEMBL
MRVIDLIKSPEKTAFSFEILPPLKGTGIEKLYETIDSLREFDPKYINITTHRSEYVYREL
GNGLYERKRIRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREDTEYVLLDLQFLGITDL
LILRGDKAKHEQVFTPEPGGYAHAIELEHQINDFNQGVFVDGSPIKAPVHPFSYGVACYP
EKHEEAPNMEQDIYWLKKKVEAGAEYAVTQLFYDNRKFFEFVDRVRQEGIDIPIIPGIKP
FSKLSQLSVVPKTFKVDLPQELALEALKCQTDEEARQLGVEWCINQCRELIAHGVPSIHF
YTVGATESVRRVAKEIY
>A0A1V3KYA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter ratti|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMENMLWESIHRLKVLKPTFVSVTYGA
NSGERDRTHSIVKTIKQETGLEAAPHLTGIDATPDELKQIAQDYWDSGIRRIVALRGDEP
KGYDKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHIIT
QFFFDIDSYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPGWLAKAYDGL
DDDPTTRNLVAASVAMDMVKILSSEGVSDFHFYTLNRSELTYAICHMLGVRPSV
>K1ALL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. GMD4S|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDSGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3D2HY37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MGEVRPDEDAENGWQEERKMSVMESLSRHNTLSFEVFPPRTEAGRRELLEPDGVLDRLNR
ESPDFLCCSYGAGGADAGKNLEVLDAVVSTGRSQAMTQLTCAGNTAEGIREQLRSYHARG
VSCVMAIQGGEGRMSRGLSDEAELVKLIRREFGNEFLVAADGAPEGEPLGSSLEGEINRL
KAIQEVGADFLITRLCWDMDIFHIWLDGIRAAGITLPVMAGVAPVVDQAATIRTALATGG
CAIPEELCRLLSDYWIYPNPFVKDPFDGEVERKRTQFREAGAAYTVRQIRLYRRWGVDGI
HFLTQNRAEDVLAIARAARDTSF
>A0A198YT27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. WYCCWR10014|TrEMBL
MVLKSDARGRNIRVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTRAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFREAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKAHNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRQQTKSAGAAA
>A0A2N2IEV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-18|TrEMBL
MRIAQLLQRQEPFLSLEFFPPKDRAQWPGFFDVVRQLRDLGPLFCSVTYGAGGSTQHNTL
EIVARMKQEYGLEPLAHLTCVGADRARLGSFLAGLVQADVKNVLALRGDPPRGESTFTPD
SEEFQHGSDLVSFIRQDFSELSIGVAGYPEKHPEAASMDDDLERLRHKVACGADFIITQL
FFDNDAYFDFVARARAVGIDVPIIPGILPVQNLGALKRMLTFCGASVPEGFMSDLEHVHK
VYGESGVRGLGLGYAKSQIRNLLDRGAPGVHLYTLNKADTCLDIWKDFLRRDGLK
>A0A2N5IRP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium imperatoris|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGIEDLKPDFISVTYGHGTHSDRTATARIANTIV
NEYRIPAVAHLTALYSDKAKIDEALDMFENAGVNTVLALRGDYIDGEQVVGAFEHASDLV
AYIRERKPNFTVFGACYPEGHYQADSLDKDIEHLKIKVDAGVTHLITQLFYDNDDFYRFC
DKVRAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPEHLDALLNRWEGNTEALHNAGIL
YASEQIADLVAHGVDGVHLYTMNHPATTRRIWRNVKSLFNE
>A0A455U5K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sulfidaeris|TrEMBL
MAITQYFFTADAYFNFVDKARALGVKQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQ
LESYGDDSEAIAAFGTDVVSRLCQRLLEARRGCTSIRLTRRRRCSRSSTT
>A0A521D0C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria faecimaris|TrEMBL
MTRPEVSFEFFPPQTLEASFRLWDTVQTLAPLEPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLPVAAHLTCVDASRQETLEIADTFARAGVENIVALRGDPPKGQDRFVPHPEGFADSV
ELIEALAETEMFSIRVGAYPDKHPEARDFSADVDWLKAKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGILPIENWKGARNFARRCGTHIPDWIENAFEKAIRDDREDLLAT
ALCTELCSDLIEGGVDKLHFYTLNRPELTRDVCFALGVTPKAELQNVA
>A0A2J8USN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pongo abelii|TrEMBL
MGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSL
CQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPI
FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEEL
TSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQ
PNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKG
ENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPS
RTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNAREMEAP
>A0A7H8SJW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NEB 394|TrEMBL
MSLLAQYFAQQQFCVLVEYLSSHQAQWPVKTQFAGFPAAMTLADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDAKTQGQKNLLLLTGDKLKQHHYSHDLKPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMTAL
QDAHAFLVQHQYAQKILACVMPLTLARAKFMLKHKVAGIVITPHMLQVLQQEKEQGLSDR
VYVRCALQILMCRHLGFAGVHLSACNQPEEQSLLERYIEEYRHLSFAECEQLWNTLWQVQ
TGTEFHPKLTYYSRPATSSQIIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDHSRAKQ
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTKILKEKLIPTVSIAVRGTSSWKNWYVEAAG
>A0A7C5PII4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSAEFELSFEFFPPKTEQGLANLLATQQALVPLGPRFFSVTFGAGGTTRARTLETILALR
QQDDRIDCAPHLSCIGSTREEIRAILDTYIEHGIRHLVALRGDMPSGMMEPGDFGYASEL
VAFIREQTGDHFHIEVAAYPEFHPQARSAREDLDWFAHKVRQGANGAITQYFYNADAYFA
FMDDCGRRGIDIPVVPGIMPITNYVQLARFSDACGAEIPRWIRKRLEAYGDDLDSLRAFG
TEVVTDLCRRLMEGGAPGLHFYTMNRAEPSATICRALGLG
>E1K2N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solidesulfovibrio fructosivorans JJ]|TrEMBL
MRHDLLTTLAKRPVLADGAMGTQLLARGAAPTACLDALNLDAPEMVRSIHLDYLAAGAEV
IETNTFGANRKKLERFELADKVLEINRQGAALARACAGDDAWVAGAMGPLGRMREEAPDP
AEIAALYAEQARALAEGGADLLLLETFFDFELLRLALHAAKSATSLPVAAQFVFGGTGLS
LSGHTMAECLRLLRREGADIVGLNCGSGPQGALDILRAAGPLEGPLSVFPNAGFPERRGD
RLVYPSSPEYFASVLVQCADHGARLLGGCCGTGPEHIRALGQALAHRAGTAPRQAAVAPG
PDTAATGRQPGKPRPCFLDRVGKGPLFLVELDPPKHLDVSGTLEGAASLASGGADAITIA
ENPLASPRLSNIALANLIRARTDVEVIVHLTGRDRNLIGMQSTIMGLACLGLENVLAITG
DPPSSGGEERLSGVYDVRSYELIGMLDCFNKGQDPQGRDMRLRTNFRIGAAFNPNTRNMA
MQVRRMRRKAELGAAYFLTQPVYSREKVDAILEETRDFPCPIFLGIMPLASLRNAEFLHN
EFPGISIPEDVRDRLRAAGDGEAREGLEIAWELMAYALPHFAGIYLIPPFNRHAVALELI
RRARGDVPAS
>A0A556CWS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. HY001|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIKEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2E3WTT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionaceae bacterium|TrEMBL
MSKIDFQQLIGSDQPVIVDGGMATALYEKGFYINRSFEELSMTESQVVREVTQSFKQAGA
QILGTNTFGAVHPKLVKYGLQDRLESILTSATEIAKEVAGEDALVAGTIGPLGLLLEPLG
PTSFDDAKNFFGRNVKCFEESGADCISLVGFHDLKELEAAVQAVREYSKLPVMLHMAIQE
SMKSSYGHSIPELVALGEKYDVEVIGFSGEVGPSGMLTAVGKLRPLTKRKISLLPNAGLP
RYVNDEYIYLCNPDYIGKFAKRFVQAGANLVGGHSGVHADHIKAIANSVRMTQSLNVELS
DSTIPAHLQPIVDEPKKEVDMEERSRLGKALCSPDEQVVSVEIIPPKGIDFENFKSHCEE
LVAAKVKFVNIPDGARAMARMSSLHMAAYVNRHFDLEPIPHFTSRDRNLIGIQSDLLGCY
MNGIRNVLLVTGDPPKLGNCPGATAVYDVDAIGMTHIVSRMNQGLDLGGTTFGQPTQFMI
GVALNPTATHRELEIKRYRYKIEAGAQYAITQPIYDVEAYAEFMEKAGADSIPVIMGIWP
LVSLRNAEFLKNEVPGVSVPDWVISEMEKAGDNKEEAVKRGMEIAVKTMEQASKMVKGFQ
VSAPFNRVKVAVDAIHGALGKS
>A0A6B0Z840|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MQFEDEPLVPGERLPIRPGHSSFGRLERVLRAGGFAVTAEIAPPDSANPAEVYERAALYD
GYVDAMNATDGSGANCHMSSVGMCSLLCRRGYAMVMQVSARDRNRIAIQGDVLGASAMGV
ASILCLTGDGVDVGDHPQAKPVFDLDCMSMLSMIRCMRDESRFLSGRKLSVPPPVFLGAA
ANPFAPPLDYRPLRLAKKVAAGAQFVQTQYCFDIEAFKRYMAAVRDAGIHEKVFVLAGVG
PLASARSAEWIRRNVPGVHIPDAIVRRLKGAANQQREGVNICLEMIHRIREIEGVHGIHI
MAYRQEHWVAEIVERSGVLDGRRPWQPPLDWKNAAWDRGHPALTDAPGRQAVEKVS
>A0A6L8I6E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boseongicola sp. SB0670_bin_30|TrEMBL
MHLPGLSFEFFPPQGVQASFRLWEAVSELSPLGPEFVSVTFGAGGAPHDLTLETVKAIMI
RFDLNVAAHLTCSGATRETTLAVADSYSDAGVREIVALRGDPPSGADAFRPHHDGFEDSC
ELISALAHLNQFSIRASAYPDPHPESPAPGADVEWLKRKVDAGASSAITQFFFEAESYFR
FRDACDAARIDVPIIPGILPIEDWRRMKRFAKRCGAHVPAWLADAFEVALRDDRHDLLAI
SVCTELCSDLLDGGVEHLHFYTLNKPHLTREVVRALRAAPTADLRYVA
>A0A7C5PIP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNEDKTFSFELFPPKTEQGMAKLQETVRRLNERRPAFFSCTYGAGGSTRERTFATVDWLV
SQGIETAPHLTCIGASRAEILEILDRYRGQGIRRIVALRGDPPSGTGLAGGELSHASELV
ALIREHHGDHFHIEVAAYPEMHPQAPNFFADLDHFKEKVAAGADSAITQYFYNADAYVHF
VDQCRARGIEAPIVPGIMPITNYSSLARFSDACGAEIPRWIRKRLEAHADDVEAIRAFGL
EVVTALCEKLLAAGAPGLHFYTMNQADPTLAIWDRLGI
>A0A523KQS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIAANQNPDARPLVKKPGYVSAGRLERVLKEGHFAITAELAPPDSALAEDVYERARVFDG
YVDGMNATDGSGANCHMSSVAMCALLTSVGYSPVMQISCRDKNRIAIQGDVLGAAAMGVS
NVLCLSGDGVQVGDHPEAKPVFDLDSMSLLETIRTMRDESKFLSGRAITTAPEIFLGAAE
NPSAPPVDYRPFRLAKKIAAGADFIQTQYIFDVPQLAQFMAKVRDLGVLDKCFILAGIGP
LASARTATWIRDNVPGINIPDEIISRLAGSENQKKEGQKICIELIQQIREIEGISGVHVM
AYRQEEAVADIIKASGVLAGRQPWYPGCESAASA
>A0A661GUI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAKDWLLSFEFFPPKTQPGAEKLARTRETLAQLAPEYFSVTYGAGGSTRDNTRDIVLETR
AAGLDVMPHLSFAFGDDDVEAVRALLNTYHEAGVNRLLALRGDLSSDTESTRKAIHANEL
VAFIREQFGDKFNLQVAAYPEIHPDAKSYKDDIYWLGEKFKAGADGAITQYFFNIDAYWY
FLDQAAKAGIDKPIVPGIMPITNFTNLARFSAGCGAEIPRWMAKKLEQYGDDQASIIAFG
SDVITQLCERLLEGGVPGLHFYTMNQAEPSVDILSRLGVNADPS
>A0A496VBF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTSQIPALTISCEFFPPRTEKGVLKLRQTREQLQALQPAYFSVTFGAGGSTQEKTFETVV
EIQEQSDFDAAPHLSCIGSSGENVLKLLQNYQAHGIRRIVALRGDKPSGWAGPLGDFRYA
NELVEFIRTETGSHFHIEVAAYPEFHPEARSAKADLDFFKQKVDAGANSAITQYFYNAEA
YFRLLDSCAERGIDIPIVPGIMPIGNYEQLVRFSDTCGAEVPRWLRRRLADFAEDKEGLQ
AFGINVVTKLCERLLEGGAPGLHFYTLNQAGPTLEITKRLGLFSLS
>A0A534AZF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPIRPGHTSPGRFERVLRAGQFAVTTELDPPDSADPEEVYRRARVFDG
YVDAINATDGSGANCHMSSLAVCALLTRVGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQAVPVFDLDSLSLLETARTLRDEHHFLSGRKISYAPRVLLGAAE
NPFAKPLEWRAQRLAKKVAAGAQFIQTQFCYDVPLLRAFMLQVEELGLLDKVFILVGVGP
LRSAKAAEWIRTHVPGVHIPDEIIRRLAGASDGALEGRKLCIELIQEIRTIKGVHGVHVM
AYRQEETVAEIIERSGVLGGRVPWYPG
>A0A4Q5V8S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTDSQPRLSFEFFPPKTSEGKEKLIKVRDQLNEFEPDFFSVTYGAGGSTRDNTKGVVTQF
KNDGINIAPHLSFGSDDEETVLKLLNEYKFFGVDRIVALRGDVPSGMGGQQQLVYANELV
AFIRKHFSTHFHVEVAAYPEIHPQAKSYSDDVRYLKGKFDAGANSAITQYFYNPDAYFFF
MEECHKVGITQPIYPGIMPIINYRNLTRFSDSCGAEIPRWLRKALENYGDDETSLKAFGV
DLVTELCEVLLENEAPGLHFYTMNQTEPTAQIVKNLGLVPVE
>A0A2A5BK94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTKSLTISCEFFPPKTEKGIANIRNVREKLAPLKPEFYSVTFGAGGSTQDNTLAAVVEIQ
QASAVTGIDAAPHLSCVGSSKDSIRQLIKTYQSHDIRRLVALRGDLPSGMREPGDFRYAN
ELIDFIRAETGDHFTIEVAAYPEVHPQAASAEKDLINFKRKVDAGADSALTQYFYNIDAY
LYFIDRCQKAGIDIPIIPGIMPINNFAQLARFSDGCGAELPRWLRKRLEEFHDDTESLQA
FTLDFLTDFTQKLIDQGVPGLHFYSMNRVDPTLTICQRLGLV
>A0A3C1SXG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTSFEFFPPRTDKGKQTLAQVRQELSAINPEYFSVTFGAGGSTQDATLETVLDIQANDG
VSAAPHLSCIGSEKAKIIELLDQYKAADINRLVTLRGDIPSGVRDIGDFRYANELVEFIK
SEYNNHFHIEVAAYPEMHPQAKNIQTDLEHFANKIKAGADAAITQYFYNADAYFRFRDDA
QKLGIDVPITPGIMPITNHTQLVRFSNMCGAEIPKWILERSKLYENDLDSLTAFGTEVVS
NLCQTLKDQGVDSFHFYSMNRTEPSLSIAKNLL
>A0A2E4KY40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTFDSKVTLKGWSIEITPKETKTISCFSAFLEEGTKVNVTSLPKTSVRDTLAAVEKLKH
DGMNPIPHITARTISDEGDLASIVEKYADLEISEVXIIAGXKDQAXGRXSSSXELISSGV
FXHFGIVNIGVAGHPEGSPDITXXQLQDALDQKNXLAXSRDLNIFLETQFCFDAXXIINW
EKAXRDRGNSLPIRVGVAGPTKLLSLINFAXKAGVGPSLKFLINXRDKLTKLVNSYXPTE
LIXXLAPQFSPXANTCFESXHFYAFGGFRKTAXFAQELFK
>A0A1T1CEB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. LM5|TrEMBL
MKVTQHIENAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVN
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPTNGGNKYASDLVSQIYQLNQGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQTDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVERHLQVLPQIFRIDLPEDLIAAVEKCKNNAEIRQVGIEWAIQQSIELKTAGVPVLH
YYSMGKSENIRQIASQIF
>A0A1H9NLT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinokineospora terrae|TrEMBL
MTTVVQRIRVGRPVFSVEFMPPRDSADEQRLWNAIRELEGLDPAFVSVTYGAGGSSRDRT
IRTTGRVARETTLVSMAHLTAVDHSIAELRNVIGWYAALGIRNILALRGDPPGDPNGEWS
AHPDGLHYADELVRLVRELGDFCVGVAAFPYGHPRSADLDADTDNLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAARGCDADLLPGIMPITTRKTLAKTIELSGAPVPARISALLEPHT
DAKSFRAAGIDLATEVSERLLAEGVSGLHFYTFNRSKATKEVVNRLGLVPART
>A0A2E6A8C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPLPPISIEFFPPKTLAGTRKLHKVREQLNVFEPEYFSVTYGAGGSTRSGTRQTVLDIRA
AGCAVAPHLSFGTDEPEVIGELIDTYRDAGIDRVVALRGDAPSGVGGSGQLRYAKELVEF
IRERTGDHFHIEVAAYPEIHPESRSVEADIHYFKEKVEAGADRAITQYFYNADAYFRYLD
LCSRAGVTVDIVPGIMPITNYVNLKRFSAGCGAEIPRWLDRQLESFGDDTETLIAFGIEV
ITTLCERLIAGGAPSIHFYALNQSDPTRQIIRNLS
>I9PLJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides cellulosilyticus CL02T12C19|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNRYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELTCEAIKCKTDEEAKQVGIEWCVKQCKELMEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A177V080|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tilletia walkeri|TrEMBL
MPATTTTTTPPTAVTPRGDESWKITAKLAKAERENRIWWSFEFFPPRTAQGLNNLYDRIE
RMSDLGPEFVDITWNAGGRTSDLTSSLVKTVHTYFGLETCMHLTCTNMPREKVDDALKDA
KEHGCRNILALRGDPPAGQSQWEAHAAGFTCARELVEHIRANYGDYFAIAVAGFPEGHPE
TTEGREKELEYLKAKIDAGADFIFTQMFYDFDIFASWVKEVRAAGITVPIIPGVMPIQNY
GGFERAVARFRTLVPQYFHDALDPVKNDDQAVRDVGTQLVGDMCRKILESDLGIRGLHIY
TMNLERGSRMLLDYLGLTPSVNQVKQLPWVPSLTPKRREEKIRPIFWANRAKSYLSRTET
WDEFPNGRWGDARSPAYGDVNAYGVSLNLTDTEARELWGAPESLDDVKALFQKFCSGDLK
ALPWSDTPVAKETSVIGGQLEKLNGRGFLTINSQPAVDGAPSDDKVHGWGPSNGYVYQKA
YLECFVAPEKLDEIIAHFDRDPQITYHAVNAQGDMRTNTQSDAPNAVTWGCFPHSEILQP
TIVESISFLAWKDEAYELGRKWAAVYEPSSPSRKLLQGLFDSWFLINVVHNDFKQPDAIF
KVFESLGVAKNGTNGHA
>A0A2E5NFV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGAPRVSFEFFPPKTPEAEASLWKTVNRLQALRPEFVSVTYGADGSTRERTHQVIKDILT
KTSLRPAPHLTCVGAPQKEIDAIADEYWSMGVRQIVALRGDPEGGAEADYIPHPEGYAYA
SDLVQGLLEKHPFELFVAAYPETHPQAISADNDLENLKRKADAGSRHAITQFFFDNEIFL
RFRDRVAAAQINVELIPGILPVTNFNTLTRFAGACGASIPQWFSTQFEGLDEDPATRQLI
AAHAAVSQAEHLGREGVDVFHFYTLNRADLSFAVCHALGVRGRA
>A0A2E9E9Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKISYEFFPPADLDFTRVASHFNELKGFQPTFLSVTFGAGGSPEDKSLGLIKELQAHTNV
NVAAHLTLVGKSIDDIDAIIQKLKILNVKTIVAIRGDSPNNLFVPAKKGFINTSDFVAYL
KRNGFEVCVSAYPEPHPESEGFDFDLQLLQNKVEAGASKAITQFCFDLPQFDRLVESIVK
KNIDVKLIPGIMPVASIKNILRMADRCGIVIPKSVTKRFNGDIEEDIKAAKELCLEQIEY
LQNLGLNDFHFYTLNRSDLTYSILKELKVNEIHEHKSRNAKSWQEERIKIRN
>A0A2E1Q4E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionaceae bacterium|TrEMBL
MKVIEHLEGRKGPLFSFEVIPPPRGKSIAQIIEMVEMLAPLNPSWIDVTSHSSVAFYKEK
TDGTIEKRTFRKRPGTLGICGVIQNRFKIDTVAHLLCLGFSQEETEDALIELNFLGIENV
MALRGDGPNFAKPTRSDRTQHDYASSLVDQIVRLRKGEFLNDLENTQGLDFCVGVAGYPE
KHFEAASLKWDLENLKKKVDVGSDYIVSQMFFDTSKYISFVNSCRELGIEIPIIPGLKIL
RSLPQLKSLPKAFHIDLPDELVGEVMDSPDHVKEIGYNWAKKQCMELLEFGVPCLHFYVM
NDCSLVTKLVKELQK
>A0A2G6KME4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSLLEIVSTMRDKQTFQSGRKLDSPPRMFLGAAANPFVDPLDWRPIRLAKKIAAGAQFVQ
TQYCFDITRLDAYMQRVRDMGLDRKVFILVGVGTLASAKTADWMRRNVPGVHIPDEIIKR
LAGAENQKAEGVRICIDMINQVREIEGVDGVHIMAYRQEHSVPEIVERTGILGDRQAWHP
RQYEGDRNVQQHLDRIQ
>A0A1G3U666|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp. RIFOXYD12_FULL_36_11|TrEMBL
MFDELINKLKNDTYITLETTPSHSPVFSPIIETIAELGLDKLVDGFTTTDNPLAKLKYNS
LFAAKMLQDRFHKPVIATMSMRDRNKIALQSDLLGANEVDVRAILALTGDPATISDQPHT
KGVFEADSTLLLDIISCFNSGIDYGGKPFTFKPKEIYPFAVINSYAKNPKTLQKKMQKKI
KHGAIGIITQPIYDIQSAKLLLELKEATEHSSSAELIFGIFPITKLRTAQFLSAHVPGIN
VPNYWIEALRVANEKGVEEEYRVGFELSKKLFEDLKALHPKIHLMTANQFQIAKDILK
>A0A534CMR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPIRPGHTSPGRFERVLRAGQFAVTTELDPPDSADPEEVYRRARVFDG
YVDAINATDGSGANCHMSSMAVCALLTRVGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQALPVFDLDALTLLETARTLRDEHHFLSGRKITHAPRVLLGAAE
NPFAEPIEWRAERLAKKVAAGAQFIQTQFCFDVPLLRTFMNRVEDLGLLDKVFVLVGVGP
LRSAKSADWIRTHVPGVHIPDEVVKRLAGASDGALEGRRLCIDVIQEIRTIKGVHGVHVM
AYRQEEAVAEIIQRSGVLGGRVPWNPGRDPPANTNRMASEPTPSAALEPARS
>A0A2E1KAN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGESKTNIIEKARPFSVEMFPPRTSEGMSKLDSVVRVLQRFQPEYLSVTYGAGGATKQGT
RDLVRSFLERGINAVPHLSFGGTTDEEMRMILDEYREFGVGRLVVLRGDMPSGIGSLAQQ
PHASDLVQFIRAETGEHFHIDVACYPETHPESKSVITDIHYFKKKVKAGANSAITQYFYN
VDAYFEFISQCQKEDIDVPIVPGIMPITNKASLIKFSSVCGAEIPRWLKKRLETFENNND
DLCKYGVEVVSRMCEKLFEGGAPGLHFYSMNRSGPLIAIIENLGLSAVSPQYNLENF
>A0A2A5D2Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIEEKKSSPKSLLPGDKRPIPAGHSTGGRLEAVLRSGGFAVTAEMAPPDSADPQDVYDRA
AMFDGVVDAINATDGSGANCHMSSMGVCSLLTRKGYAMVMQISCRDRNRIAIQGDVLGAS
SMNVANILCLSGDGIKTGDHPEAKAVFDLDSMTLLKVIRRMRDKSQFMSGRKITKAPDVF
IGAAANPFAEPLDYRPHRLAKKVVAGAQFVQTQYCFDMPIFKDYMKRVVDLGLAEKVFVL
AGVGTMVSAASATWIRHNIPGINIPNHIIKRLKDSKNPKHEGQEICIEIMQQLKEIEGVS
GIHLMAYRQESTVKDMVLKSGILDGRKPWRPSYN
>A0A3M1WXP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAVAAPLPKNVEVSFEFFPPKTAEAEASLWRAIKRLEPLRPRYVSVTYGAGGSTRERTHA
TVVRLRRETALEPAAHLTCVDASRQEIDAIARRYWEEGIRHIVALRGDPPDGQSRYVPHP
QGYAYAADLVAGLKRIADFEISVAAYPEKHPEASSLQADLDNLKRKVDAGASRAISQFFF
DIGTFLRFRDRARAAGIDIPIVPGILPVTNFARVVEFAGRCGASVPRWMAELF
>A0A7W8QE77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia atlantica|TrEMBL
MTSLTMNPIELSFEFFPPKTQEGIDKLRATRAELVSLKPKFVSVTFGAGGSTQQGTLDTV
IDMAKEGLEAAPHLSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGAVGELRYAS
ELVSFIRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAY
FRFVDDARQLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRA
FGLDVVTDLCQRLVDANVPGLHFYTLNAATSTKAICERLAV
>A0A7Z2VF07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. badrii|TrEMBL
MMHQDTPRPASTFIDAYSLEVGANDVDALSAVAPRIMPGSRIAIPSLPGQDTATRLAAAC
AVRALGFTPMPHLVARRIASLDDLQAFLRRAVDEAGVEHCLVIAGDPSSPIGPFPDSVSL
IATGVFERAGIQSIAVAGHPEGHPAMHAGAHWEVLERKCRSIAERGMAPLIVTQFAFDAD
LVLRWLETLRARGIDAPVRVGVPGPAGVAVLARYAARCGVSASAAMLSNYGISIGKLLGT
AGPDRFVDRLTAGLTNAHGDVRLHLFPFGGIARSVAWVEHYRSRSRLTHPVNL
>A0A7C3CG22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacterales bacterium|TrEMBL
QALGIRNLICITGDPPRMGSYPGATAVFDVDSIGLVNIVNNLNQGLDIGGNAIGSQTTLL
IGVGANPGALNLDEEVRRFEQKVKAGAEYVVTQPVFDVRLLENFLRRIEDFRLPLIAGIW
PLTSYRNAEFMVNELRVPVPDTFLERMRKADSAEAARAEGVAIAREMARQVRPMVQGVQI
SAPFGRYELAIRVAEAIGPR
>A0A7G9LMX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter cryaerophilus|TrEMBL
MFETLISKLQDGKYLTLETTPQHEPSMHNIVEKIKKFKIDSKVDGFTCTDNPLAKLKYNS
LFAALKLQTEFKKPVIATMTMRDRNKIALQSDLLGANDFDIRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFAVVNAYAKNFGSLEKKMNLKI
QNGAVGVITQPVFDIENVKKLLESFEIAKENVEGDKRKAQLIFGVFPITKLRTALFLSAQ
VPGIHVPQFWIDELEKAHNISEEEEYKVGMQLSKNLFDEINRIHPKIHLMTANNKFEVAS
EILA
>A0A2G5WHG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. P13|TrEMBL
MSLLKKLQTNVLTADGAMGTILYSYGIDYCYEELNIEKPEIVEKIHQDYITAGADIIQTN
TYSANAVKLARYGLESRVTEFNKAAIQIAKRAAAPGGQFVLGTIGGLRGIRKSDASLDEI
QKVVLEQANALLTGDPDGLLLETYYDFEELSSVVTTLRQITDIPLIAQVSMHDPGVLQNG
LSLNDALHQLESLGADIVGVNCRLGPYHTIQAFENVLLPDKAFLSAFPNASLLDVEDGRI
VYESEAEYFGRAAVLLRDQGVRLIGGCCGTTPKHIKAAKTRLEGLAPVTEKVVTPAKPII
IQEAGPVKHQPLHEKAKTERTVIVELDTPRHLETEDYIKGANLLYDAGVDAVTMADNSLA
SPRISNMAMGSIIKMQHNIRPLVHLTCRDHNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELLQLIKQLNEGISFSGKPLRKKANFSVSAAFNPNVRVIDRAVQR
LEKKIEAGADYFITQPVYTKEKIIDVYEATKHLDTPIFIGIMPLTNIRNAEFLHHEVPGI
KLSEEVLERMRECGDDREQSTATGIEIAKELIDTAAKYFNGIYLITPFLRYDMTLELYEY
IKEIDEKKERELTHAETSY
>A0A6J3LEV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bombus vosnesenskii|TrEMBL
MKKFVSKDKVHDPCIDDECDNIADHFRSVDTKREMIDLRKKLQDIIKTDAIFCSFEMMPV
ISKDLLQSFFTEMNKYHPLFYALTWHKNDMKDYLSLDIFNILPNNTLLHLIAKDLTSTDV
KIILKEALEHGICNVFVLRGDSTKSNSEFSHAIDLVRFIRNQFGNIFCICIAGYPEMHPE
SSSKEMDLIYLKEKVDAGANFIITQIVFEASIFIKFVSDCKNIGINIPIIPGIFPILNYT
CLQKMARICNIKIPKIILNTLECIKDNDEEVHNYAVEIATNIIKKIIASKTACGFHFFTL
NKPSLSLEICDKLNIFH
>A0A150F8W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus nakamurai|TrEMBL
MGLLEDLQHRILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANYIKLSRYGLEDETKKINQEAVKIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LGEALRSIADIGADITGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
ETDNTYFRESAVEFRKQGARIIGGCCGTTPNHIRAMAEAVSGLEPITEKEVKIRREEEVI
AVRDERAEPGLNEIAAKKRSIIVELDPPKKLNFEKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTGFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHKETKHLQTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDGIREKMALAGEDKQKQKTEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELASYI
KQKDEKRANVYLH
>A0A6G2WJI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8369|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PEALKERILAAKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A366BZ21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum sp. BSW8|TrEMBL
MTAPRVSFEFFPPQSLEASFRLWEAAQALAPLKPAFVSVTYGAGGTTRKLTHEAVQTIHT
HYKLNVAAHLTCVDATRAETLEIAEAYAAAGVTEIVALRGDPPKDQGAFRPHPEGFANSC
ELIEALAATGSFRLRVGAYPDPHPEAGSADADVLWLKRKFEAGADSAITQFFFEAETFFR
FRDACEKQGIDGAKIIPGILPIEKWAGVRRFAERCGAHVPPGIDAAFQTAIRDGREELLG
KAMATELCSELMEGGVRDFHFYTLNKPHLTRDICHALGVLPEAHLEKVA
>N9PWD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 2168|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GQGTPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1F6CG59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Handelsmanbacteria sp. (strain RIFCSPLOWO2_12_FULL_64_10)|TrEMBL
MRISDAFAAGRRVFSFEFFPPKTEEGVRSLFETVSELAPLDPTFVSVTYGAGGTTRELTI
DLATRIKQELRLETMAHLTCVGHGAAEIESILEVLEARGIENVLPLRGDPPRGETQFVKP
VDGFAYAQELVRFIRARYGFCLGGACYPEGHLECPNGEEDLDHLREKVDAGVEFLITQLF
FDPDHYFDFVERARNRGITLPIVPGVMPVTNVGQIERFTSMCGASIPAPLQARLDVIRND
DEAVVNTGIDWATEQCRRLLEGGAPGIHFYTLNRSRSSRTVYLNLNGARQ
>A0A552Z7R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVVNRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>C1FN88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum (strain Kyoto / Type A2)|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIKNILALRGDIPKDKDIIGE
YNYAFELIEKIKASNNFGISGACYPEGHIECKSLDQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQEKSINVPIQAGVMPVVNKKQIERIVKISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDIAV
>A0A5B8URJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter ginsenosidivorans|TrEMBL
MKITEHINAAKGKTLFSFELLPPIKGNSIQSIYNAIDPLMEFNPPFIDVTYHREDYIYKQ
HENGLLEKVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTREETENALIDLQFLGIDN
VLVLRGDARMADSGFIPTPGGHSYATDLLQQVVNMNSGKYLYEDHEVVNADFCIGVAGYP
EKHFEAPNLKTDFRYLKQKIDMGANFIVTQMFFDNNKYKEFVTLCRESGINVPIIPGLKP
ITSSKQLISLPKIFHIDIPEDLSDLIHNCKSEKEVREAGIEWMIDQCKELVEFGAPVLHF
YTMSNPGPTRKIAEAIF
>A0A7X2SY69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter agglomerans|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSDME
>A0A0M2HFF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium trichothecenolyticum|TrEMBL
MAHSIPVSPQAASLVNGFSLEMTGKDIAGLEEARELIPQGTKINVTFLGNEDLEMRVAAA
KAVKEMGFVPVPHLSARRLRSQDELEEFLGRLQEVGATEHVFAVGGDPAEPEGPYPDSLT
VIRSGVLQRFGVREVSIAGYPEGHPDISDDVLWSHLDEKALALAQQGLDAVILTQFAFDT
DPVMTWIDAVRARGIDTPIRIGTPGPAGIKRLLGFARRFGIGANAMIVKKYGFSLTNLMG
TAGPDRFVSDLATLLADDPGSGDVKLHFYTFGGLAATSQWAREFVAAQSSGARR
>A0A6G7PWD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosulfuriphilus ammonigenes|TrEMBL
MEKVREALARKEFIFTFELVPGRGSRGKAYDQLVAFAEAAARGGRLHALSITENAGGHPA
LAPEVLGREIKALGLETIIHFSCKDRNRNQMESHLFAWDREGFHTILVMTGDFPRVGFGG
QAKPVFDLDSVQTLALISRLNQGYVIRNGQRLPPTSFFKGCVVSPFKRLEAEVMTQYFKL
ERKISAGADFVITQIGFDARKFDELLRYLRLRNLEIPVIGGVFVLDLPLARIMHRGRIPG
CRVTDELLAKIEAESEAPDGGLSARLLRAAKQVALLKGLGYAGAHICGPNLTYEQVEFIV
EKALELTDNWLEFVPEFTFAPEGTFYLFQKDPRTGLNTDDLTPRAPASSSPWHYVINRLI
HDNFFLPDGPLFSFTRRLFLSLADSPLAGMLDSLEYFVKKILFDCRSCGDCTLGELAFLC
PQSKCAKYLLNGPCGGSYDGWCEVFPGKRRCLYVQAYERLKAQGEEESLARGMVPPRDWA
LNGTSSWINYFSGRDHHRLGDKK
>A0A7W0CVN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. CGMCC 1.13658|TrEMBL
MTLSLSQMEEARRALDAPLFAGLPGDIGVSFEFFPPKTEKMEAQLWESVQTLAPLGPRFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEASRAEIDAVAEEYWAAGVRHIVA
LRGDPPVAGEPFRAHPGGYANAAELVAGLRSLHPFEISVAAYPECHPDSGTQVADLDNLK
RKLDSGATRAITQFFFSPDCFFRFRDAAAAAGIESEIVPGILPVSNVAQTRKFAGLCGAE
IPGWMDRLFEGLDDRPAARQLVAATLAAELCRKLYAGGVRHFHFYTLNRAELAYAICHLL
GLRPVATAQEKAA
>A0A1C7E3R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus maritimus|TrEMBL
MMLLDELNKRMLTADGAMGTLLYSYGIEYCNEELNIQRPEVIEKIHRDYIAAGADIIQTN
TYGANAHKLARYGLEDQVESINKAAMAIARKAAKDSGQFVLGTIGGIRGIRKSDATLDEI
VAMVDQQAQHLLSGDPDGLLLETYYDFEELAATVTHLKKLTDAPLIAQLSMHEPGILQNG
MNLNEGLKRLDALGAEIVGVNCRLGPHHTIQAFEGVELPEKAFLSAYPNASLLDIEDGRI
VYESEADYFGRAALLLREEGVRLIGGCCGTTPKHIEAVKKRIGHLQPITEKKVEEKKPIV
IREAEALKDKPLHEKAKTERTIIVELDTPRHLEIDKFLEGSKALDAEGIDAITMADNSLA
SPRISNMAMGSILKHQQDVRPLAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSLELIQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVVERAVAR
LEKKIEAGADYFISQPVYTKEKIIEIHEATKHLETPIFLGVMPLTSIRSADFLHNEVPGI
KLSEEALDRMRACGDDKEQATAEGIQIAKELIDTAAQLFHGIYLITPFVRYDMTVELIRY
IRQLDLEKASDRAYA
>A0A7C4EVT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomonile tiedjei|TrEMBL
MKSESRLERVLRAGHFAVTAECGPPKGSDVAKLEAKARHLQGKVDAVNVTDNQTAIVRMS
SVAACALLKNMGIEPVLQMVTRDRNRIALQSDLFGAYALGIRNVLCLTGDHQSFGNQKGA
MGVFDLDSIQLLSVVRDMRDNGHILGGEPIETPPKMFIGAAENPFADPLTWRAVRLAKKI
AAGADFIQTQCIFNIDRFEAFMQQARDMGLTEKVYILAGITPFKSAAMARYMSEKVAGMD
IPDEMIKRMAGAPKEKQAAEGIQIAVETIERVKSMKGVAGIHVMAIEWEHKVPEILEAAG
LSQRPEV
>A0A3B8W6I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagales bacterium|TrEMBL
MKVVDHLKNANGKTLFTIEVLPPLKGENIRSLFDNMDPLMEFKPPFVDVTYHREEYLYKK
RENGLLEKRSTRKRPGTVGICAAIQNHYKVDCVPHMICGGFTREETENALIDLQFLGIDN
VLALQGDAIKSEARFVADPDGHAFASELLGQIMDMNAGKFLDDDLQHASPTNFCVGVAGY
PEKHFAAPNLKTDLKYLKLKVDMGAQFIVTQMFFDNQRYLDFVRLRREAGITAPIIPGIK
PITTKTQLSVLPTIFNCNLPEELTEEIDRCKDNKEVKEVGIRWAVQQCKELIKHEVPSLH
FYSMGKSDPIYRIAKELF
>A0A2T5PB94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mangrovi|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLVVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRQLLSTYRENGIRRIVALRGDLPSGMGQAHGELRYANDL
VEFIRQESGDHFHIEVAAYPEMHPQARNFEDDLQNFARKCRAGADSAITQYFFSADCYFY
FVERAQKLGLDLPITPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIASIQAFG
EEVVTRMCERLLDGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0F7JVL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sedimenticola thiotaurini|TrEMBL
MHSQQTDQKLFSFELFPPKSEEGMEKLKTQVKKLARINPLYVSVTFGAGGSTQQRTFQSV
EWLVTEGIEAAPHISCVSSSEVEIVEMLTRYRAQGIRRLVALRGDLPSGTGMSGRGELNY
ANELVALIRREFGDYFHIEVAAYPEFHPQAANARVDLENFKRKVAAGANGAITQYFYNAD
AYFRFVDSCKELAIQIPIVPGIMPITNYSNLSRFSDACGAEIPRWIRKRLESYADDVESI
RAFGVDVVSELCQRLLDQGAPGLHFYTMNQSAATLKIWDNLNLPE
>A0A0B1Q5R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas altamirensis|TrEMBL
MSATSSAQRSNLRVSFEFFPPKTPAMEETLWSSVQRLAPLEPSFVSVTYGAGGSTRERTH
QTVKRILEETHLAPAAHLTCVDASKDEVDEVVRQYRNTGVRHFVALRGDSQAGAGAAFVA
RPDGYRNGAELTAGLKAIDPSFEISVSAYPEKHPESPDFATDIDLLKRKVDNGASRAITQ
FFFDNDTYERYVERVRRAGIYVPIVPGIVPIHDFTKIRRFCSAIGASIPTWLAERFEGLE
NDPQTRAHVAAAVCAEQVLDLTRRGISDFHFYTMNRADLVYSICHILGMRPRSEAAPASG
EAAA
>A0A1I1UMW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermophagus xiamenensis|TrEMBL
MTTVAELIRNTNKPSFSFELLPPLKGNSIQRVFNTIDRLKEFSPLYINITTHRDEIVYKK
NDKGIIERRVYRKRPGTVAVAASIQNKYQIPVVPHMICRGFSKSETEYALIDLNFLGIHD
LLLLRGDNSSRHEFVNDEKKEENAYAIDLIHQVNDLNSGRFLDGTLMEPFATPFSYGVAG
YPEKHADAPNLEADIYWLKQKVEAGAEYVITQMFFDNEKFFSFVKKCREAGITVPIVPGI
KPINLKNQLNILPKVFHTEIPEPLAHELRKCKNNEETTIVGTQWAIMQCKELLQNGFHLI
HFYTMMATQSVYNIAKEIY
>A0A127K7B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera humireducens|TrEMBL
MSIDISIEFFPPNTAEGADKLRATRDKLAALKPAFFSVTYGAGGSTRERTFATVKEIAAA
GYEAAPHLSCIGSTRDSIREILREYADAGIRRIVALRGDLPSGAGAAGEFRYANELVEFI
RAETGDRFLIEVAAYPEWHPQARSPKDDLLAFKRKADAGANSAITQYFYNLDAYLHFVDA
VRKLGVDIPIVPGIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDADAIRAFGLDVV
TRLCEKLIAEGAPGLHFYSMNMAGPTIEICRRLGLHH
>A0A2G6RNJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. 13|TrEMBL
MHPAQLGSAGNITHAYSLEVSAKDMPALSAAAPRIAPASTIAIPYLPREDNAARLAAART
VRGLGFEPMPHLSARRIASFAGFESFVQRAVAEAGVKRCFVIAGDPSTAMGPFSDSAALI
DTGVFERAGMKVIGVGGHPEGHPVMSKAEQWDVLERKCRSIAQRGMTPLIVTQFAFDADI
VLTWLKALRERGIEHAVRVGVPGPASIAVLARYAALCGVSACASMWSKYGVSIGKLFGTA
GPDLFVERLAAGLTEAHGVVSLHFFPFGGIAQSVKWIEQYRSRADPAPG
>A0A8J7EJC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nodosilinea sp. LEGE 06152|TrEMBL
MGYRLRTAAQAGQFLVTAEVMPPKGGNPEHMLAMGQVLKGRVHAVNITDGSRAVMRMSSW
AAALLLQQQGVEAVCQVACRDRNRIALQADLMGAYALGVRNILALTGDPIKAGDHPEARG
VFDLESVRLLKLLDKLNCGVDSNDKPLTDGALDLFAGAAIDPQLSSWSGLQRRFEAKVKA
GAQFFQSQLITDFDRLGKFMDQVASGYDRPVMAGIFLLKSAKNANFINRNVPGVTIPQTI
VDRLAAAADPLQEGVQIAAEQVQAARQVCQGVHLMAVRREDLIPQILDQGGVAPVDAALA
QG
>A0A6G2RIW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4951|TrEMBL
MALGTASTRTDRAHTVRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVRHPDGVGYAADLVRLIKESGDFCVGVAAFPEMHPRSKDWDTDVAHFVA
KCRAGADFAITQMFFYPEDYFRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A847DR05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnobacter sp|TrEMBL
MTTHAAEQHRSNGFPIDLSFEFFPPNTDAGAEKLRDVRARLAALSPDFFSVTYGAGGATR
DKTLATVTAIADEGRAVAPHVSCIGATRESIAELLALYRERGIRRLVALRGDLPSGMVDT
GDFRYASDLVEWIRRQTGDEFRIAVAAYPEVHPQARSAEADLRAFVTKMRAGADLAITQY
FFNADAYFRFRDEAGRAGVDAPIVPGIMPINNYVQLARFSDACGAEIPRWIRSRLAGYGD
DIESIRSFGVEVVTDLCRRLLDGGAPGLHLYTLNQAEASERIIGALRGGGRAGARR
>A0A7Y9DNS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineococcus aurantiacus|TrEMBL
MTLVEDLRAARRRFSVEFSPAHDEATAARQWRAVERLGALGPVFASVTYGAGGGDRAGTV
ELASRTARETPLRPVAHLTAVGQSAAQLAAVVDELVEGGVRDVLALRGDPHGDPRAPWEP
HPEGLAHADQLVRLALARGVEGVGVAAFPLGHPESPDADTDLRHLLGKFAAGAGFAIAQL
TYDVEDFLRLRDRLAAAGCDAPLVPGLLPVTSPRVLEVTRRLTDGHEPSWLNQRLAPLLD
DRGAFREEGMRVAVEDGRRLLAEGVEVLHLYSLNAASNVEALVGELGLADAREGTCRTPV
VP
>A0A0S9NE51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. Leaf280|TrEMBL
MASSASLNLADARALLLSPLGPVARAGSNRDAVRVSFEFFPPKTDEAEANLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIITETSLRPAAHLTCVEASREEVDEVIEGYKAIG
VDHIVALRGDPPGGAGIGGVYQPRADGYANATELTAAINRIGGFDVTVGAYPERHPESPS
IDHDIEVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFVGLQ
RMCDACGASIPDWLKAHFEGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETAAAQ
>A0A2L0HWP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ACNIH2|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSNDHFHIEVAAYPEMHPQAESFDLDIQRFCDKANAGANAGLTQFFFNPDAYFYFV
DRIQKEGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A365PU95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas zhaodongensis|TrEMBL
MSQTRSHSFSFEFFPTKTDAGHEKLLATARRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVSTAPHLSCVGDTKAELRELLNIYKDAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARHFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVDMPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIESIQA
FGTQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAVWENLKLVR
>A0A359G5K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp|TrEMBL
LRGDKSQNEKRFMPHPQGHAHAVDLVRQIAAMNRGQFVDGEVEECHHSRFSIGVAGYPEG
HDEATSPEADIAALKAKVDAGAEYVVTQLFYDNACFFDFVRRCREAGIGVPIIPGIKPLA
TVRHLTLLPETFGCRIPDDLRREVEAHRDDKAAVRRIGTEWAIAQSRELKAAGVPVLHYY
PMGKAENIIEIAKTVF
>A0A4S8F5X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lampropedia puyangensis|TrEMBL
MTPTSSNTVQRIPLSLEFFPPKTQAGAQKLRDTRTELYVLHPEFCSVTYGAGGSTQAGTF
TTVAEILAEGQAAASHFSCIGATHEKVRAELQELKTMGVNRIVALRGDLPSGYGIGGQFH
YASDLVAFIRAETGEHFHIEVAAYPEMHPQAHSPQKDLQAFAAKVQAGANSAITQYFFNA
DAYLRFRDDTHRLGLNIPIVPGIMPVMGASQLLRFSDACGAEVPRWMRTRLQSFGDDVNS
IRAFGLDAVTALCERLIREGAPSLHFYTMNQSPLVLEISKRLHLI
>A0A542IRB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. SLBN-100|TrEMBL
MSPPSLIDTHPNLSDAAPVALSYELFPPRSPAAAETLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIIGELLDTGVRGILALRGDLPKD
GGEPVSGALRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEEHDVEVLL
AKQRSGADFAITQVFFHSGQYADLLARARRAGVTIPIIPGVMPLTSLRRLNRLGELAGVE
PAPELMERLAGADNDIERLHIGVDATVDLANAALDAGAPGIHLYTFNEHQSALEVLDKLA
LPRHSRSGIRRDALVRRQLAS
>A0A3D8HDE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides acidifaciens|TrEMBL
MKVIDLINNSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSIQKVNIRKRPGSVAIASAIQNKYNITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTIEAGQNTDLYHEHATDLQEQVNNFNKGIALDGSRFEANETPYSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDEEAKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVYKVAKEVY
>A0A3F2RSU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora kernoviae|TrEMBL
MKVIDKINASIERQEVFYSFEFFPPKTPAGVENLYARMDRMAALEPLFCDMTWGAGGSSA
QLTTELSANAQKLSGLEMLMHMTCTNMAAGDIKKALDQAKEAGIQNILALRGDPVRGATS
FDECDRGFSHAVDLVRYMREEYGDHFCIGVAGYPEGHTESEDKAADIKYLKEKVDAGADF
IITQLFYDVRVFVEFVKECRAVGITCPIIPGIMPIQNYGGFERMASFCNTYVPEEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSSRAAESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELAESH
FAATNTSTPKERRGMWGEAPATKHDICQTFVQYVRGEISSLPWCDAALHAETSTVQHELA
SANAAGFLTINSQPRVNGALSDDPLFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
SSVQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYENGSQSAKLLREIHDTYFLVSIVDNDFGADKGTYVMTCGQDKTVKLWNPHRSGVE
NDNEALLIKSYEGRHGYDVQDVAIAHDNAKFASCGRDRDVFMWDVPTAKVIRKFEGHKQS
VNCVRYNADSSVLLSGSYDKTIRAWDIRARNAYTPIQVLDDFKDSVTSMVVTDHEIIAGC
VDGVVRTFDLRAGQISREHIDEPVVSVAHSPDARFVLAGCLDGSIRVIEKANGTEVKR
>A0A1I4VHP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora antimicrobica|TrEMBL
MTADAELLQQSLNNARFEVLPLKGVLAQAELLPAGTTVTVTASPGKGIEATLDLAARLRD
RDLHVVPHLAARMIGDRAHLTALLDRTDDLGITEVFVVAGDSPVPHGDFPDALALLRAMD
ELGRRPDRVGITGYPERHAFIPDATTVRAMTDKARYADYVVSQICYDPQTVASWVKAVRA
RGVLLPIHLGVPGVVDVRRLLRISLRIGLGESIRYLCKQHGVVSKLLTRYTPEELFDGLS
PHLVDPSCGIAGWHFFTFNEIAKTVQWRHDLIARLREVPA
>A0A2L1IFE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SWI36|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFESDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2L2LC63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MPDISTASIIPASIEASPAQVLGSTDLAGLFPQGVRVYLTDTGAASQERLVEAAGHLRDL
GYEPVPHLAARRMPSGTAFEEQVKRLAGEAGVTDVLVVGGGVDRPAGPFASSMDMLSTGI
FDRCGIRQIAIAGHPEGSPDFNDETAMAALRLKRDFAERSDAAMHIVTQFGFDPARFIAW
AEGLAASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTTLAKGHSPES
IVGPIERHWQANPQGAIRQIHVFPFGGLQNSADWLVKRGSWQTGAVDRSASPDSMTG
>A0A2P9IF46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura parvosata subsp. kistnae|TrEMBL
MPFEPICEIEPPTKPDLKHVRHQIGTLSKIAHAFLIPDNHIGRATVSSVAVAHEVEAMGG
RGIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTSGNRTGDLNVRSMIEEARAF
SADFRVGAAAGLRPLPAWKRTADFLFSQVSFSVEQQLRWREAHPVDVPVYAGVMVLASER
HARTLAAAIPDIALPEELIARVAADRMAGVEAACEQVLALRDSGAFAGVHLVPVARYRDV
ESRLAGAL
>A0A446UTA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Triticum turgidum subsp. durum|TrEMBL
MKVIEKIQEAAANGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPNFCDITWGAGGSTA
DVTLDIANRMQNMVCVETMMHLTCTNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFSCALDLVEHIKAKYGDYFGITVAGYPEAHPEVILGEEGATEEAYSKDLAYLK
RKVDAGADVIVTQLFYDTDIFLKFVNDCRQVGITCPIVPGIMPINNYKGFVRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNL
GLIEESKLSRTLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWGDSRNP
SYGALNDHQLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPETTIIDDQLVK
INSKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFP
SLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRG
WACLFPEGDSSRELLEQIQKSYYLVSLVDNDYISGDLFAAFKEI
>A0A6D2AD99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira bourretii|TrEMBL
MNQILLEVIPRDVSTLLSEVSYVKNNFSQISGINIPDLLRFETRSWVAASKIQNIFPNVI
PHLRAIDFDLDHCDHIVEFLQKNNLSSVVVIKGDPPTDMSRKVYQTTSTKLIKKLKKEMS
SLKVYAAVDQYRSGIKEEFDYIEMKIDAGADGFLTQPFFDLRLIDIFTEKLRGKEVYIGI
SPVTNEKSQSYWESRNRAYFPKDFQLTMDWNVKFAKEVIGYCSQNDFNTYLMPIRINLEV
YLGGIFK
>T0JE01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. UNSWDHB|TrEMBL
MKISEILKKGKPTLSFEFFPARTEKAAESLNKTIDDLVELKPDFVSVTFGAGGSTKDGSY
ELVKKLKKEKEQEVVAYLAAFALKKDEITAVLNNYNDLGIENILALRGDPPKDVDVTQVP
VESFKYASELAAFIRQNYSFCLGVAGYPEGTLMHQVLRRTSNT
>A0A6N4SYU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Undibacterium sp. KW1|TrEMBL
MKTPNFSIEFFPPKTAEGTEKLRVTRAKLAELNPKYFSVTFGAGGTTQQGTLDTVTEIRR
EGHDAAPHLSCVGGTRESIRAILNEFKANDIRRLVALRGDLPSGYGMGGEFRYANELVEF
IRAETGDWFHIEVAAYPEMHPQARSPQDDLNSFVRKMNAGANAAITQYFYNADAYFRFVE
EARKAGVTAPIVAGIMPITNSTQLQRFSEMCGAEIPRWIRLKLASYGDDTASIKAFGLDV
VTAMCERLLAGGAPGLHFYSLNQAAATTAIWQRLI
>A0A7Y5JS35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dermatophilaceae bacterium|TrEMBL
MAHGTASSMARAERFTRSIPAMIEADTPTFSFEFFPPKDDAAEAQLWDAIRRLEKVSPSF
VSITYGAGGSTRDRTVRLTQRVLEETSLTPMAHLTCVGHSVTELRSIVGAYAAAGVRNIL
ALRGDPQGGLGQPWVAHPEGLDHADELVTLVKGLGDFTVGVAAFPDGHPESRSVEEDART
LIRKEQAGAQFAITQMVFDVDNYLRLRDELARRGSQMPVVPAIMPITNARQVVRMAQLAG
QPMPAAVTDRLDRHGDDAVAVRAEGMAIATESSQRLLDEGAPGIHFITMNRSSATLEVFG
NL
>A0A658JM91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. 1XD8-22|TrEMBL
MGLREALQTKVLTADGGMGTLLYSYGLDYCHEEMNLTRPELIEKIHSEYIAAGADVIQTN
TYGANAIKLARYGLESQVKEINEAAIKIAKKAVQSGDQFIIGSIGGILGVRKSDTTLNEI
LTTVREQAEILIDGQLDGILLETYYDFEELTETLKLLRTMTDIPIIAQVSMSEPGVLING
IKLNDALQELENIGADIVGVNCRLGPYHTIQALETVELPKRAYLSAYPNASLLDIEEGRV
IYESEVDYFARAALELRNQGVRLIGGCCGTTPKHIEAVKKQLSNLKPIEQKRTKPEKEVL
IREPEPRNTEPLHEKVKRERSVIIELDTPRHLEVDAFVEGAKILYKEGADIIMMADNSLA
SPRVSNIAMGAILKQHGIRSMPHITCRDRNLIGLQSHLMGLNALELHDILAVTGDPTKVG
DFPGATSVYDVSSMELITLIKQLNEGISFSGKALRKKANFSVAAAFNPNVRVLDRAVSRL
EKKIEHGADYFISQPVYSKEKIIEIYEATRELEAPIYIGIMPLTSFRSAEFLHYEVPGIK
LSDEVLERMKACDGDKEREAEEGIAIAKELLDTATQYFNGIYLITPFLRYDFTLQLMQYI
KQLDEETKGVKVNG
>H1QPL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces coelicoflavus ZG0656|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSAAWDTDVAHFVD
KCRAGADYAITQMFFQPDSYFRLRDRVAAAGCDTPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A1H6LGI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rheinheimera pacifica|TrEMBL
MAFANAQYLDAINRNLQDVEGKVNVSFEFFPPKTPQMEQTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASKEALIDIARDYWQNGIRHIVALRGD
LPPGSIAKPDLYAADLVEILRSVADFDISVAAYPEVHPEAPNAQFDLLNLKRKVEAGASR
AITQFFFDTEKFLRYRDRCAAIGIDVDIVPGILPVTNFQQLKKFAALTNVAVPTWMHKAY
EGLDNDVTTRNLVAANIAMEMVKVLSREGVDHFHFYTLNRSELSYAICHLLGVRPQTAV
>A0A1Q6KG53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium 41_12_two_minus|TrEMBL
MKVNEILSNGKITLSFEVFPPKTDAQFESVRKATIDVAALKPSYMSVTYGAGGNTRKNTV
AIAKGIQDTTGVTTIAHLTCVGATKENIHNTLDEMKAAGIENVLALRGDRPRDFEGDPFV
DFHYASELVSEIKAYGDFCVGGACYPEGHVEAANKSEDIINLKKKVDAGCEFLTTQMFFD
NNIFFNFLYRVREQGISVPVIPGIMPITRAKQVETARDLSGCSMPQRFLNLVDRFGSNPK
AMEQAGIAYATDQIIDLIANGINHIHVYSMNKPQIAEAIQKNLSEILK
>A0A5B8NVD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. sy039|TrEMBL
MSFSSVPASYQRTITDVISTVNPGRVPFSVEFMPPRDDAAEQRLWKAAEVFHDLGAAFVS
VTYGAGGSSRERTTRIAHELAHHPLTTLVHLTLVNHTEEELVSILTEYAQAGLSNLLALR
GDPPGADPLGPWTKTPGGYEYAQELIELTRRLPQTQHFQVGIASFPEGHFRAPSLAADTE
VTLAKLRAGAEFSITQMFFDVEYYLRLRDRLLKADSEHGAKPIIPGIMPITSMRSLARQT
ELSGAHVPSRVHEQLRRAAECGGDDEVRKVGIELSTLMAERLIAEGAPDLHFMTLNFARA
TQEVLHNLGMAPAWGAALGHDAVR
>A0A4R3V473|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelomonas saccharophila|TrEMBL
MTTPVSFEFFPPNTPVGVEKLKTVVRELGALSPQYFSVTYGAGGSTRDKTLSAVMDIAAA
GFEAAPHLSCVGSTRENIAEILATYRAQDIHRVVALRGDLPSGTATAGEFRYASELVSFI
RETQGPDWHIEVAAYPEVHPQQRYAAKDLQHFADKMGAGANGAITQFFFNADAYFHFVDE
ARRLGVTQPIVPGIMPFHNYGRIAQFAQRDGIDMPRWVQMKMEGFMDDAAAIRAFGLDVI
TRLCERLIDGGAPGIHFYTLNQSALTLELCKRLGLGG
>A0A238XDH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceibacterium sediminis|TrEMBL
MTRPEISFEFFPPKNIEATFRLWDTVQVLAPLAPRFVSVTYGAGGTTRDLTRDVVSTLHK
HSGLRTAAHLTCVDATREETLQIARDFAAAGVTDIVALRGDPPKGANGFAPHPDGFNSSV
ELIEALKDAGDFTIRVGAYPDKHPEAPTATADVEYLKRKLDAGADEALTQFFFEAETFFR
FRDACVKAGIDKPIVPGIFPIENWKGARRFAESCGTQIPAWVIDAFDTATRDGREDLLAT
AVCTELCSDLIEGGVDKLHFYTLNRPELTRDVCFALGVAPDVKLENVA
>A0A4R0WNX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia strydomiana|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLALLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHLSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCRRLISAKVPGLHFYTLNGAAATTAICERLGG
>A0A2S4XHJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ru73|TrEMBL
MALGTPSTRTDRARTVRELLASGKRSYSFEFAAPKTEKGERTLWKAIRRIEAVAPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSVADLRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWVRHPEGIEYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELADRILAVKDDPAAVRSIGIEYATELCARLTAEDIPGLHFITLNHSTATLEIYENLG
LHQQT
>A0A6N9VCF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lipmanii|TrEMBL
WVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSEDWDTDIRYFVDKCRAGADYAI
TQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVFPRKLE
>A0A6N9VCF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces microflavus|TrEMBL
WVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSEDWDTDIRYFVDKCRAGADYAI
TQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVFPRKLE
>A0A6P1MGL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminipila terrae|TrEMBL
MKIKEIYEKKQVLSFEIFPPKRDIALQNIDETLEVLCSLNPDFISVTFGAGGSSNNNRTI
ELAKRIKKDYHIEPLVHLTCLTYGKNEIDEFIYQLNENGIENILALRGDRNPELKEKEEF
LHASDLTGYLKKKTNVCIAGACYPECHPESENRIEDIKNLRTKVSAGADFMVTQLFLDNN
RFYSFYEDTRIAGIDIPISAGIMPVINKAQIEKMISLCGVSLPEKFRRIMNKYEHNKEAL
FDAGMSYAIGQVIDLLASEVDGIHLYTMNNPKVAKKLCDGIKTFI
>A0A850A1X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineales bacterium|TrEMBL
MGPHPLEFFTDRAKFTQEWEAYFYKLRQPDWWQGDAQYHPPAYEKPISQLEAHLRSGAFV
ATAEIAPPLGASGEIIKKKVGWLQGYVSAANFTDNASASARMNSMASSKICLDAGLEPVM
QLQARDRSRVVIEADAMGAAGLGIHNLLCLSGDHHRFGPNPMSKPDQFDMDAVQVLWMLR
RMRDEGIYLDGRAIKERPQWFLGAAASPFGAPPKFEAIRAEKKVNAGAQFIQTQPIFDYD
RFLDWMEALDKRNLHDKVYILAGLIPLKSARAAHFMADEVPGVVLPAEIVKRMDAAGDKE
GQQEEGVTIALELIEKLRRTPGLNGMHIMAVHWEEIVPRLIEESRIGSQ
>A0A8G2JEF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobaca bogoriensis DSM 18756|TrEMBL
MPAPRVSFEFFPPKTLEASFRLWDTVRMLAPLSPSFVSVTYGAGGTTRQLTHEAVTTIGA
QFGLNVAAHLTCVDATRDETLAIADSYAQAGVREIVALRGDAPKGQARFTANADGFANSI
ELIEALSATGHFNLRVGAYPEPHPEAADTLADVRWLKRKFAAGADSAITQFFFEAETFLR
FRDTCAREGITGRIIPGIIPIENWSGIRKFAKATGASVPAWLDEAFEKATRDGREDLLAT
ALCTELCDKLVREGVEDLHFYTLNRPHLTRDVCHALGVVPQVSLEKVA
>A0A229UR20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus rigui|TrEMBL
MKLDLREALRQHILVGDGAMGTYLYQMGFPVGISYEELNLLKPDVIADVHRRYYEAGARI
IETNTFSATREKLSKYGLEQEVEAINRAGVTLARNAVGSDAYVVGAIGSIRGGKRKNVRT
SKVKEDFRQQIEVLLDSGVDGFLLETFYDLEELLLVLKTIRKLSELPVICQFATEGTGTT
QDGVSLPDAFAKLKQSGADVVGFNCRSGPNGLLRSLERVTGLKEELPFSVFPNAGIPDYV
DGRFTYAATPQYFAETALRFADLGARIIGGCCGTTPEHIAAMAKALEGYTPHLAKPSADA
SAARTAAPGVEKAAMVQTEPVLTVVNGSGSADDAGTEEPNIVDLVKQRHTVIVELDPPRD
LDIEKFMQGAQALKEAHVDALTMADNSLAVTRMSNLALGYLVKEQTGLRPLIHIACRDRN
MIGTQSHMMGLHALGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGVAFS
GKALKRKASFIVGAAFNPNVKYLDKAVQRLERKIEAGADYIMTQPVYNTELIEKIYESTK
HLDVPIFIGIMPLASGGNANYLHNEVPGIQLSDEVRQRMGDLKGEEGRAMGVQIAKELLD
CAMQYFNGIYLMTPFLSYDMTVKLTNYVWEKSGRTVSTCTH
>Q05VS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. RS9916|TrEMBL
METTALQRNLAAGAATITAEVMPPRGGDVSHTLAMAEALRGRVHAINVTDGSRAVMRMSS
LAVCRLLLDAGLEPVLQVACRDRNRIGLQADLLGAHALGIRNLLCLTGDPVRAGDQPAAR
PVNELESVRLLRQVTAFNRGEDPVKERLPDGPTALFAGAAADPHCPSQSGLLRRLERKRD
AGARFVQTQMVMDAAVLEDFCRQVAEPLELPVLAGVFLLKSAKNALFINRMVPGACIPES
LIARLDAAADPAAEGIAIAAEQVRSYLGVAQGVHLMAVRAEERLPLVLDQAGISPLASV
>A0A0J6BFX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. GFB01|TrEMBL
MLLQRALTSGQVAITAEVTPPRGGDPSRTLAAAEALRGWVHAVNVTDGSRAVMRMSSLAV
CRLLLDRGIEPVLQLACRDRNRIALQAELLGAHALGLRNVLCLTGDPVRAGDQPDARPVN
ELESVRLLQLVGQLNAGRDPVDGMLPDGPTVLFPGAAADPQSASWSGLKQRTRRKHEAGA
RFLQTQMVMDPEALRRFVGEIAAPLDLPVLAGVFLLKSARNAAFINRVVPGAAIPQVVID
RLAAASDPAAEGIAIAADQVARYLDIAQGVHLMAVKAEERIPLILERAGLGPLASPIQEA
SSRTAAISSPG
>A3Z343|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. RS9917|TrEMBL
MVSALQRVLLSGEAAITAEVMPPRGGDPSHALAMAELLRGRVHAINVTDGSRAVMRMSSL
ALCRLLLDAGHEPVLQMACRDRNRIALQGDLLGAHALGIRNLLCLTGDPVKAGDQPGARP
VNELESVRLLQQVTAFNSGLDPVKETLADGPTSLFAGAAADPHASSWSGLSRRLERKRKA
GAQFVQTQMVMDAAVLERFCRELATPLELPVLAGVFLLKSARNAQFINRMVPGACIPEAL
IDRLARAENPAAEGVTIAAEQVRRYLGIAHGVHLMAVKAEERIPEILRQAGVSSEAVNSQ
AVNSQRS
>A0A1Z3UBR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas vesicularis|TrEMBL
MASSASLNLADARALLLSPLGPVARAGSNRDDVRVSFEFFPPKTDEAEANLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIITETSLRPAAHLTCVEASRDEVDEVIEGYKAIG
VDHIVALRGDPPGGAGIGGVYQPRADGYANATELTAAINRIGGFDVTVGAYPERHPESPS
IDHDIEVLKAKVDAGASRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLQ
RMCGACGASIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETAAAQ
>A0A0Q1CLP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. ACN1ag|TrEMBL
MTAVRSVSAKPATMGEFLASGRPSFSFEFFPPRTPEGERHLWTALRRIEALRPSFVSVTY
GAGGSTREGTIRVTERIATDTTLTPIAHLTAVNHSVAELRQVIGNYAGAGVRNVIALRGD
PPGDPQGTWTAHPQGLEHADELVRLVKSVGDFCVGVAAFPDKHPRSPDFDTDARYLVGKF
DAGADYAITQFFFGADDYFRLVERVRALGCDKPIIPGIMPVTNVAQIVRMAQLSGAAFPP
VLAARLQAVADDPAAVRAVGLEVATELSRRLLDGGAPGLHFITLNRSSVTREIFEAVR
>A0A1S1U118|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. ORS 3428|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIREFADFGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGVLPVHNFTQVANFSARCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>M7UVH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryotinia fuckeliana (strain BcDW1)|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHHIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAAL
EEVKNDDAAVRNIGKDLVAEMCRRIIEAGVHHLHFYTMNLAQATRMVLEELSLTPSNQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLESGIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHEP
DLTYYAVKKTGDVQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLNEPFETSESGD
VDGVRFIEPQTVPLTNGEANGH
>Q4WEL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)|TrEMBL
MEKITDKIAALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSEE
YNTHGEDDSNKDFTFAVDLVRYIRKMYGDYFCLGVAAYPEGHPVDSYQDVQDPVRDLPYL
VEKTLAGADFIMTQLTYDIDAYTKFEQMLRNHESGAFKTIPIIPGLMPIHSYKILTRTTK
LSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLNLEKT
VSFIIERCGLIPDYPEDSGAVVDDDYTTAPTGAQHRSLSRRRASSVNSLPHNRVIVDRLQ
VPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQISEGQGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVSGAVARRIWGYPVSREDISALFRHHVSGDLYIVPWSEGGAEENSS
GLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFF
CPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWG
VFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRVYPRGTPTERLLEEVKNDVWLVCVVG
QDFGAGTENGSEEEQQETKWMWNVLINSQ
>A0A3D4PPX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MSAESPTHCTPRVPFSFELYPPRTASSEEALHETVRKLAAAGPDFLSVTYGAGGSNGGRS
LEVLRFIRENTDVEPLAHLTCVGNTYQGAARLIREFLDAGILSFLALRGDPPLGQTEPFL
GDLESAAQLVQLIDRAQAERAPYEESPVPGFPGAARVAPRRKANIAVAAFPNGHPRAVHR
TQDVEALLAKQAAGATFAITQLFFHPDDYLAFVERARAAGVTIPILPGIMPITSPNRLAR
VLQLTGEELPSELSIALEVEPTTEGRREIGIEWAARLSREVIAGGAPGIHLYAFNQHETV
LTVLAEAGVLPALRH
>A0A7C6MJQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MSEFPSPAVGRQVPIRHALTLPSPGPIPFSVEFMPPRDDAAEERLLRAAEAFHDLGAAFA
SVTYGAGGSSRDRTLRIAERVSRQPLTTLVHLTLVGHTVDELRTILRSYLERGLTNLLVL
RGDPPGDPLGDWVPTEGGLNYASDLIELIRSEEEFADFEIGIASFPESHYRAKSVEDDTK
YTLAKLRAGAEYSITQMFFDVEHYLRLRDRLAEVDPEQAEKPIIPGLMPITSLRSVRRQL
ELSGSKLPSALEDRLVGAAAGDEEANRAEIRKVGIEVSTEMADRLISEGVPGIHFMTLNF
ARATQEVLHNLGMAPAWGSGQDMVRGGF
>A0A7C9LBT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sediminimonas qiaohouensis|TrEMBL
MTTPRVSFEFFPPKDLKGSFRLWDTVQVLAPLDPQFVSVTYGAGGTTRDLTRDAVSTLHE
SSGLNVAAHLTCVNATRDETLAIANGFSDAGVRDIVALRGDPPKGAGGFTPTEGGFANSV
ELVEALTDTGKFTIRVGAYPEKHPDAADTAADVEWLKRKLDAGAAEAITQFFFEPETFFR
FRDACEKAGIDKPIIPGIIPIENWSGVRKFAASCGTHIPGWLDDAFEKAKRDDREDLLAT
ALCTEMCSDLIEGGVDALHFYTLNRPELTRDVCHALGVTPRVQLENVA
>A0A8H7X8T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cadophora sp. M221|TrEMBL
MEKITDKIAALPPGSNYFSLEFFPPKTTMGSSNLRARLDRMSRALRPLFITVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRKLVDRALEDAKALGIRNILALRGDPPRSEE
YRDAGENGNGNGEVDTEEEFEWAVDLVRYIRKQYGDYFCIGVAAYPEGHADESDPAGQSL
EHDLPYLVGKVQAGADFIMTQLFFDVEAYDGFEKRLREHESGAFKDMPIIPGMMPIQSYQ
MIKRTTKLSHARMPPDVMARLDEVRGDDEMVKKVGVDIVSEIVTHIQKEPSPGPRGFHFY
TLNLEKAVAFILERTNLIPSSPLDSESAILDVPSPLESVQINGSTNKRPSRRLSSIGSDP
HNRVIISGSKTSNPDRETTAEEAAVPAEPVNTRANTLAISEGEGSLGREATWDDFPNGRW
GDARSPAYGEIDGYGVSLHMSVNQAIKLWGFPTSREDITSLFIRHIEGSISALPWSEQGL
NEETNTIKSQLLKLNQKGWWTVASQPAVNGVKSTDPIFGWGPKNGFVFQKAFVELFIPVA
DWTALHAKLTSSTVAPTVSWYASNASGSFLSSSPNSPEDVGAGSGSTNAVTWGAFTGKEI
ITPTIIEEVSFRAWAEEAFGIWGEWGRVYPARSVSKGVVDGCREGYWLVNVIHHGYVESE
GLWELLLN
>A0A1D7QYV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salisediminibacterium beveridgei|TrEMBL
MLETFYDLDEILFVIRKIRKISDKPVIANLTMGDIGVMQGGIPVKDALTACEEAGADIVG
LNCRMGPYHMLQSIEQVPLPEGRRLSIYPNASLPNVRDGRFFYQSNPGYFKRMTRSLVQE
GARLIGGCCGTAEEHIRAIRQAVDDGKLVPIEFKKDVTPAPQLEAVAPEKRPKPLPDIVK
EKTSVIVELDPPKSLALVPKFMEGVEALTDAGADAVTLADNSLAVSRVDNFALGMRMKQE
KNARPLLHMACRDRNIIGMQSHLLGLHTAGIHDILTITGDPAKVGDFPGATSVYDMASMD
LMRLVKQLNEGMSFSGKDIGEKTAFSVGAAFNANARRIDREVKRLEMKVEAGADYFMSQP
VYDPERFKEIHEATKHLNVPIYMGIMPLVSSRNAEFLHYEVPGITLTDDVRERMARLDGD
KEASAREGIALSKYLLDAALPYFNGIYLITPFLRYELTAELTRYVHQASVSLEQEGRSL
>A0A254R054|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanicola sp. 22II-s10i|TrEMBL
MSVPAVSFEFFPPQTLEASFRLWDTVQVLAPLKPRFVSVTYGAGGTTRDLTRDAVATLHK
HSGLPVAAHLTCVNATKEETLAIAEGFAEAGVTEIVALRGDPPKGEGKFSVYPGGFAHSV
ELIEALAATGKFTIRVGAYPEKHPEAASGAADVEYLKRKFDAGADEALTQFFFDTDHFLR
FRDACAKAGIDKPIVPGIMPIENWKGIRRFALNTGTSVPAWLDEAFEKAIRDERQDLFAT
ALCTEMCTKLMAEGVEKLHFYTLNRPELTRDVCHALGVTPEVQLENVA
>A0A0D5M9D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. KO116|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTREVVR
AVGESGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRTETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKVVDNLTD
>A0A349HE40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Competibacteraceae bacterium|TrEMBL
MDSQKHYPKQISCEFFPPNTDEGMAKLAAARKALMPISPAFFSVTYGAGGSTRERTLQAI
QGIRANSDVDAAPHLTCVASTRAGIREILTTYRKLDIRRLVALRGDLPSGMSEFGEFRYA
NELVEFIRAETGDHFHIEVAAYPEFHPQARTTERDLLNFKRKVDAGANSAITQYFYNPES
YFRFVDDCEKLGLDLPIVPGIMPITNFSQLARFSDNCGAEIPRWIRKRLESYGDDLSAIR
AYGLDVVTDLCRRLLAAGAPGLHFYTMNRAGPTLAICERLALIRG
>M8BCR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium tumefaciens str. Cherry 2E-2-2|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNPEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLATAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYK
PHPEGYENAAALVKGLREIADFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A0E1PRU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii NCGM 237|TrEMBL
MISTLPMSHVSPCFQQNQFFMLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAP
LEASKSYPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQ
PRSRYLESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLG
YDIEALKQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQ
AGHTDRVYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWS
SLWQVKTGKEFTPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWE
NALIAKLLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEF
GDRECIHSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A415LRF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF37-6AT|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A285BHY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterium sp. RBIITD|TrEMBL
MMFKDESLCNKLNRGEFIITAEISTPKGADITKTIEEARKLKGIVDALNITDCPMANMRM
SPIALAHLLQNHLNIETIFHLTCRDRNLIGLQSELLGAYALGVRNVLALTGDDPSRGDTP
TATGVYDVDSIGLLKIVNSLNNGYDYSGNKLESSTEFCIGTTANPNDLTEKAIDKLKSKI
DAGVAFIQTQPVYDEDILFKFIKKIEALNIPVLVGVLPLKSYKMAVNLNKKVPGIDVPEH
IIEKLKIKGKEEGINIAVEFIKNIRNNVGGIHVMPLGKVDVVADIASRIDNMEFKLSEKK
VETN
>A0A7K7DI67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pheucticus melanocephalus|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRRVLQGRRGEVFDHMGAGGPLFIDVTWHPAGDPGSDKETS
SMIIAYTAVNYCGLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEE
VDGFNYAVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQ
LFFRPETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIK
DNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLP
WAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYL
KSKSPREELLKMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLK
EQLERVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVRALLKV
LRKYELRVNYHIVNVKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAF
ALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A813VUE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachionus calyciflorus|TrEMBL
MNQVEISQILETFKTDKLQSPQIKSNRPEPLSRNFSLQSSSANVVQLSPTINVYESLIDK
IKRKIENKETWFSLEFFPPKTVNGASNLISKLEFLGSGRPLFCDITWHPAGDPSSDKPTS
SMKIANVMLNYCQLETMLHITCYGQTKESMKQYLDKAKSIGIRNLLALRGDPAVGSEWKV
QENGFNYATDLVKFTKENYGDYFVICVAGYPHGHPDSPNYEQDLIHLKEKVDAGADFIIT
QLFFKPEKFLTYVEDCRRIGINCPIIPGILPIQSYDSLRHICKLSKLEVPENIVNALEKI
KDNDEAIRIYGIETAVQLCKDLMNAGVLGLHFYTLNREVAVTEILRRLDLWNSETPPRDL
PWKSNQLCSYPRQAEDVRPIFWSIRPKSYVCRTSDWDQFPNGRWGNSSAPSFGDLKDYHI
FYSKVDSKKCLAQWGYELNEEIDIWEVFECFVAGKQNKNGVKITNFPWCEEGLALETNLL
QNELERFNRQGILTINSQPNVNGAPSSDPVIGWGSSDGYVYQKAYLEFFINSSYLPFLLK
SLEKYTRVIYHIINKSGDINLTNCTLLSPNAVTWGVFPGKEIIQPTVVDPISFVSWKDEA
FNIWTDLWGRLYEPNSKSRQLLEHVSNAYLLVNIVDNDFQKENCIWSILNEMLEMKIQNE
QSQQ
>A0A0M4H3F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. oral taxon 414|TrEMBL
MSTFPAAPGAPTSPAAGAGSAAGAGPGPAAGAASGAADAVAPRPPSERASCDRAEAGPAG
PSLSLELFPPRPGRHATQTWGALDRLLGAGPDFVSVTYRPAFVITGAPPGAPGRDAAPAA
RVRVVRERNPAEDVVAHVLATSAVPLMAHLTCIGYRRASVVEIVRAFLDMGVRRFLALRG
DPPRGFAADDVAGELAHADDLVRVIREVEADYFDDGARHLQIAVAAYPAAADRGREIEVL
AAKRAAGADLAITQVFYDVEDYLALARAADRAGVDLPILPGIIPLTDLRRLTRLEALSGV
RVPEHLVRTLERSAGARTTAAGIDATLRLAAGVLDGGAPGVHLYTFNRTRPALDIVSHLR
LGRILDGRRPDPLTQREVWRSYLNAVPGDDAPTARMPGAARP
>A0A3N2AVS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrococcus jenensis|TrEMBL
MSRLRYSFELYPPRDEAARLRVEAAVDAFAALEPEFVSVTFGAAGTSTSHSLDVLQRLLD
GGASPMAHLTCAGLEVDETGRLVRQFLDAGITKFLALRGDPPRDGDVRPKRTLASAAELV
QLIGRVEAERMPYAETPLPGLRAPILGERRGAALGARRAATEIAVAAFPNGHPGAGTRRS
DVDALLAKQSAGATMAITQLFFDPYDYARFVELARSRGVTIPIVPGVVVPTTVRRLIRSA
ELAGEGVPRVLAEQLEAASPDDARRLGVDAAVALIGALAEHDPGAVHLYTFNDHRPAIDV
LAGVGALPLTAPTPTGAP
>A0A4Q5L4W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium FWC3|TrEMBL
MASHTTNGKLYSFEFFPPKSEESASALRVTVDKLARLRPRFCSVTFGAGGSTRERTFETV
VEIQGRTGIECAPHLSCVASTRENIREVLDRYRVQGIRHIVALRGDLPSGMLSAGEFRYA
SELVAFIRQETGDHFNIEVAAYPECHPQAPNIELDIRNFKRKVEAGANSAITQYFYNPAA
YFRFVDDCRKSGIDIPIVPGIMPITNYTQLARFSELCGADIPRWIRKRLEGFGDDRPAIR
AFGIEVVTDLCRALLDGGAPGLHFYTLNQSEASLAIWDNLGIAAA
>A0A831KPN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MTFREKLEQKKFAVLAEFEPPKGADFSEMLTNAINVKGRIDAFVVPEMATAVMKASSLGG
CLSLQINGLETVFQVCCRDRNRLALQADILSAAALGIPNLMVVKGDDITVGDHPQARAVN
DIDVFELLEAVDQMQNGKDMAGIELKGAPDFFVGALFNAGAQGGLFDLELEELEKKINLG
VKFVITNPVFDLKILERVLKRLDKDQVALIPKVLLLKSAGMARYINRNMKNISIPENLIK
SIQKAPDKARECIKIAAEIIKQIKNMELPGVAISTMGWEDKLPQILDESNIV
>A0A8I1IBJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum sulfidophilum|TrEMBL
MTAPRVSFEFFPPQTLEASFRLWEAAQALAALKPAFVSVTYGAGGTTRKLTHEAVQTIHN
HYGLNVAAHLTCVDATRAETLEIAEAYSAAGVSEIVALRGDPPKGQGAFRPHPDGFANSC
ELIEALAATGRFRLRVGAYPDPHPEAGAPDADVRWLKRKFEAGADTAITQFFFEAETFFR
FRDACEKQGIDGAKIIPGVLPIEKWAGVRRFARRCGAHVPTHVDEAFETAIRDGREELLG
KAMATELCTDLMEGGVRDFHFYTLNKPHLTRDICHALGVLPDAHLEKVA
>A0A0F8IAX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina mazei|TrEMBL
MPVTSVMGVVTKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDYPTC
GDHPGSKPVYDVDSVQLIELVRKLDTGVDFAGNKLDGGTSFCAGAVSGIDPEKTMQLIKL
QKKVKCGADFIQTQAVYDIGMFEEFMDAVNYLEVPVIAGLIPLKSLGMAEFMNKNISGIH
VPEEIMLRMKDASSPMEEGLLIASETIKELTKLSRGIHVMPIGSHRNTARLLSLAGISQK
>A0A1Y6MDG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium malacitanum|TrEMBL
MENVDQTTQTESELRVRYNDITRGVYFIGTTPPKTSTPLEEVEGIADRLVNRIKDLAIDG
LIVYDIQDEVSRTQKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSETDAFDEWL
NEAWHEYQVRDIVLVGSPSAKNEVSLPLSAAYQTLAENNNNFFTGGIMIAERHAKKGNEH
ARLIEKYQQGCNFFISQAIYDTQATIDILTRYAIECKQDGIKPQRILLTFSPCGSAKTLE
FIEWLGVSVPEATSLRILNASNPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRK
EEIDGSILLYKLLRASMDSHLAKHEFRTLQRNKLLSV
>A0A1J1IHF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clunio marinus|TrEMBL
MKFHIINKQKIFSKTPLKKIILENFCRENGKFFYSIEVTPKEETKIDFTKLKIQPLFVDI
TWIKNFNLITPIEDAPALKLANEIKSTHVVNSVTCYGLEDHHIEKVLRSELKLKNFTVLR
GDYVDSEQKYKFANELIKEIRRRTSSEEVTIFCAGYPNTHNEAVNADEDLQNLKRKVESG
VDAILTQVVFSSSKFVDFIKNCRRVGISQDIPIIPGLYIPFNFNELNLMLNIAKVKLDHG
IYQSFEQLKDNNEEFKTFSLNFMIKVISEIQETSPEFIRGFHFFTLNNFEMVEKLIEIVN
FSEM
>A0A831Y103|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MPTQNIFTASLFEPEEFTITYELVPGQGSGGRRVEKLLEFAAQAGQDGRIKALSITDNPG
GHPALAPIAIGSEIRKTGIEPLLHFSLKDKNRSQIESHLFLYHRQNFNNLLVMGGDFPRI
SYHGQALPVFDLDSVQTLQLMRDMEEGTYRSGFKNARPAFDPITFNRGCVVSPFKMTESE
QVWQYAKFLQKKRAGAHFVVTQLGYDICKFEEFIRFLRESGITIPVLGNVFIPSLAVARY
MGKGQVPGIVFPEQLILQMEQEEASGSREARLVRAAKLICVLKGLGYSGVHLGGNGLSFD
NVKFILDTSEELGTNWDMLRRDVHFPVPDTWYLYPPARTGACGKDKTSLTPGRKNAAQRP
HRLTHKMFFSPPNITSRLFGKICLYCAKSRRRTAMLRIFERWIKGLLFYCRMCGDCTLAE
STYICPQSGCPKKLLNGPCGGSRNQACEVFPDRFCFWVREYNREDPDATIEKLGSLPFMH
PKNWALDQTSSWINFYNGTDHNRISFDKDSH
>A0A7X1L9T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSVANLYKDAGDKPIISFEFFRAKTEKAEQNLEKVLDLLSETKHDYMSVTFGAGGSTREG
SYELIDKLKNDRGLNVVAYIAGIGLGPDDLTEVLDKFKNQGIETVFVIQGDEPQGDVAFQ
SHPDALAHATDLLAFIKDRYDFRLGAAGYPEGHINAESLEKDIEYAKLKQDNGAEYIVAQ
YFYDNRFFYDYVDRCRAIGVTIPIIPGIMPIYTVKLLEILTSVCGSSLPDDVRNGLDSIP
ADDKEGVVQFGIELATQQCRELLKHGVPGLHFYTMNRGKSVNGIVNTLQNEGLL
>A0A7X1L930|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MPSAFKKALDSGKFVVTCEAAPSKGTNLEKMTHHIELLKDKVDAMNVTDHQSSVMRFPSL
GGALLVKELGGEPILQMTCRDRNRMALQADLMFASSRGVHNVLCLTGDSVMLGDHKEAKP
VFDLDSSQLLAAVRTMEKGRDMSGNELDGGVRFCAGAIVTPEADPIEPQLIKFEKKLEAG
AEFIQTQAVYDMDNFKKFMEYARQFPVKILAGIILLTSAPMARFMNKNVAGVTVPQDLID
EMKSAPKGGALNKGIEIAGRMVRQIKEENICDGVHIMAIGKEEKVVDIMEAAGLL
>A0A836T4P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilus sp|TrEMBL
MTIRYEANPPKILPEINTDESITKFIKKIKIISEKCDAIHLTENVLGFQRVSPIKIGKII
RTEIPDLPITVSLRVRDKNEKEISEFVNNCISIGISGILILMGDPSQSGKQDSGQIPSTV
VKRLREQGIDSQIDLYLSISNKPNFSKITKKIEANPKGFMTQVIQNLEQVQNLANYLKEF
LIIPIILFPSEKNEKSAKFLNLDLSEYSQKFEELVRKTHEITGDVLITSPSDFNGLSEFL
EKLDN
>A0A7V0JKH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSFQKRLVAGDFVVLAEFDPPKGVDASDLVSNLIKIKGRVDGVIVPEMAQAVMRMSAMGG
AALMEQHGMETIMQICSRDRNRLALQGDVLAAYFLGIKNLLVVPGEEIMYGDHIDAKQFA
DIDELTLLRAIKGLQNGVDMAGMELKGSPKFLTGCSIKPAKNEIALEAELELTQKKVKEG
AQFLVTPPVFNINAFTYFMEKAKGLGIPVIATVFLLKSVGVARYISTNVPGPPIPEEMIS
RLRKAPDRINECINIAGELITSLKELCQGVQLVTMGWENRLPAILDAAKI
>A0A3N5FKF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MRLKSKLEKGEFAVLVELEPPKGVDVSLMLANAKKVKGKVDAFVVPEMSNAVMRMSSLGG
ALILNGNGLETVFQVNCRDRNRIALQADLLSAGAVGINNVMAVKGEDPRFGDHHETKSVN
DLDLLELIRTVNILNNGKDMAGIELAGAPRFIVGSTVNAGAGGQALMLELDEMKKKLDAG
TGFFITQPVFDVSGIRPFLERVDRSKIRIIPTVLLLKSVGMVKYIERHMDNIKIPGATID
RIQNAPDRVRECIKIASENVSMLKKEGFSGAFISTLGWENKLPEILE
>A0A5R8LYV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter aurantiacus|TrEMBL
MKVTEHIKQAKGKTLFSFELIPPVKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
KGGLLEKKVTRMRPGTVGICSSIQHKYHVDTVPHLLCGGFTKEETEYVLVDCHYLGIDNV
MALRGDSMKEERYFVPTEGGHCYAKELVSQIRNLSRGEYLHETIDSDDNADFCIGVAGYP
EKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKFFEFVEAAKNLGITVPIIPGIKP
IAVKRHLQLLPQVFRIDIPQDLIDAVEACQNNKDVRQVGIEWAIQQSKELKSAGVPVLHY
YSMGKSDNIKAIAREVF
>A0A3N5JEW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
QFVQMVKKMREEGRFQGGADIENPPQMFVGAAANPFADPFELRVARLAKKVAAGADFIQT
QCIYNVDKFEKWMEGVCQRGLHQKCYILAGVTPLKSVGMARYMKNKVPGMDVPQEVVDRM
AGVPKDKQAEEGLQICVETIQRLKQVQGVAGFHIMAIEWEQKVPEIVERAGLFPRPKVD
>A0A421JRR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spathaspora sp. JA1|TrEMBL
MKISQKLQQAHAGPNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSTLTNEMVYTAQSALGLETCMHLTCTNMQIELIDEALDKAYKSGCQNILALRGDPPLD
GSESTGDFKYAKDLINYIRKKYGDHFNIGVAGYPEGHPEEESEIKTLHYLKEKCDAGADF
IVTQMFYDADNFIDWCKKLRKIGVEIPIIPGIMPISTYSAFVRRAKWSEIAIPQHFLDVL
DPIKDDDYLVRERGTELVSDMCIKLLKSGCVNHLHFYTMNLEKATVMILEKLNLIDAVKS
HDVVGASELPWRKSLNPGRSKESIRPIFWQNRKYSYVTRTATWDEFPNGRWGDSRSPAFG
DIDLCASELLRQSPKRALELWGIPQTLKNMSDIVVSYLKGDLKALPWSDGPVGEDTKIII
DDLIQLNKKGFFTMNSQPSLNAVKSSEKVFGWGPKNGYVYQKQYLEFFCHKDIIAKLLYK
IDAFNTKEGDTSSSVISYYAVDKDGNLTTNCKDDDINAVTWGVFPGEEILQPTIVEKTSF
LAWKDEVYRLFSEWGNVLGSNLAGADPEKVKDFLELMNTLSNDFVLCNLVNNDFIDDDST
IFKLIEELDVKDLV
>A0A3N5FF49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MTIQKRLQSKEFVVLAEMNTPKGVDISRFVTDARRIKGRIDGIVVPDMDNGVMRMSALAG
GVLVQQQGLEAVIHVYGRDRNRMALQGDLLAAHVLGIQNLIVVHGDDMANSDHRMAVSVD
DLDELGLLAAIRSLRDGKDLAGFDLDGQPEFNVGCRLAPFADEAAMNSELDLAKEKIAAG
ASFIVTPPVFDINRFQNFMQKASILGVPVIPMVFLIKSVAVARYIATNEPGAHISEELIR
RIRKSQDREMEGVKIAGETISQLRKTAQGVLIQAMGWEHRLSAILDAAGI
>A0A3A4PW82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSLKKKMSAGEFAVMAEMHTPKGVDISEIVTNARRLKGRVDAVVIPDMDNGIMHMSALAG
GVLMKQQGLEAMIHVYGRDRNRMALQGDLLAAHVLGISNLLVVRGEEMINGDHRDARIVD
DLDEVGILNMIRTLQGGLDLAGFELKGAPEFTAGCAIAPVVDDAQLAAEIESAKKKVAAG
AGFVVAPAVFDMAYYAKMIEKLKPLGVPVVATVFLLKNVGMARYMAINDPGARVSEDLIT
RIRKAPDREAECVRMAGEMAAALKKTAQGIKIVTLGWEHRLPAILESAGL
>A0A344TR07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Runella rosea|TrEMBL
MTKITDYIQQANGKTLFSLEVIPPLKGSSIKELLANIEPLMDFKPPFIDVTYHREEYIEQ
MLPDGTVKHIVTRKRPGTLGICSSIMHKFGVDAVPHVLCGGFTREETEDFLMDLHYLGID
NVLVLRGDPAKPYKTFKPKTNGHEYASQLVEQVANMNKGQYLHEGVEALAPTDFCIGVAA
YPEKHFEAVDFDVDFEYLKQKIALGADYIVTQMFFDNSKYFEFVKRCREAGITVPIIPGL
KPLSTKKQLSVLPRIFYLHMPDDFVKAVEACENDVQAKQIGIEWCTQQCKELMAFGVPVL
HFYTMGKSENIYKIASQLY
>M2VIF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri NF13|TrEMBL
MTASNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDTKAELRELLNLYKEAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRELGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQA
FGEHVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A0D6B0Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum sulfidophilum|TrEMBL
MTAPRVSFEFFPPQTLEASFRLWEAAQALAALKPAFVSVTYGAGGTTRKLTHEAVQTIHN
HYGLNVAAHLTCVDATRAETLEIAEAYSAAGVNEIVALRGDPPKGQGAFRPHPDGFANSC
ELIEALAATGRFRLRVGAYPDPHPEAGAPDADVRWLKRKFEAGADTAITQFFFEAETFFR
FRDACEKQGIDGAKIIPGVLPIEKWAGVRRFAQRCGAHVPTHVDEAFETAIRDGREELLG
KAMATELCTELMEGGVRDFHFYTLNKPHLTRDICHALGVLPDAHLEKVA
>J9QZ69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Riemerella anatipestifer RA-CH-1|TrEMBL
MKVTEHIKKSEGKTLFSFEILPPLKGQNIKCIFDAIDPLIEFNPSFIDVTYHREEYEYVE
VRDGLLEKRVVRKRPGTVGICAAIQNKYKVDAIPHILCGGFNREDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKNGNAYASDLVKQIQEMNQGIYLDTSLEKAAPTNFSIGVAGY
PEKHMEAASFSQDIGHLKKKVEAGADYIITQMFFDNQKYFDFVDRCRSEGIEVPIIPGLK
PIATKSQLSLIPHRFKVDLPDDLVTAITKANNNTEAKEIGVEWCIEQSKDLMKNGVPILH
YYSMGKSESVRKIAEAIF
>A0A559NPL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter sp. MAR_2009_72|TrEMBL
MKVTDHITNAKGKTLFSFEIVPPVKGKNIQELYNNIDPLMEFNPPFIDVTTSREETVYVQ
KEGLLDKKTTRMRPGTVGICASIQHKYNVDTVPHVICGGFTKEETEYMLVDCHYLGIENV
MALRGDARSEQKYFEPTHGGHSYAIELVEQIQNLNKGKYLHETVEAEHSSEFCIGVAGYP
EKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEAARNLGINVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIEAVDQCATNKDVRAVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAEALF
>A0A6I5PGA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. SIO3F4|TrEMBL
MTISNGSHKTSSLLRSAVSDGQFVITAEVMPPKGGNPSHMLEMAKVLKGRVHGVNITDGS
RAVLRMSSLASAVLLKQAGIEPICQMTCRDRNRIALQADLMGAHALGIQNVLALTGDPVK
AGDHPKARGVFDLESVRLLRTIGILNQGLDLNEKKLPDGPLDIFAGSAVDPQCPSWSGLK
KRFERKVEAGAQFFQSQLISDFECLEKFMTEIAAPAQKPVLAGIFLLKSAKNAAFLNRNV
PGVHIPDDIVNRLAEAEDPLKEGIAIAAEQIQVAKILCQGVHIMAIRREDLIPEILDRAG
IAPIFNAPVSTNGANKTVPSQQDLAMV
>A0A838XJA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium phoceense|TrEMBL
MPDSLDAALDDPILQALAADRPAVSFEFFPPKDDEGEAQLWRTIADLSPLEPTFVSVTYG
AGGTSQDRTVRITERIAREAPMPPVGHLTLVGQTRGEIETVLKQYVASGVQHVLALRGDP
VGGPRAPWEPHPDGMDHAIDLVALVHEVGGLSVGVAAFPEGHPDCSGLDADADVLVAKAR
AGASFAISQLFFRADDYFGLVRRVRDRGCDLPIVPGIMPILNFGQVARMAELSGAEMPRE
VLDQIEPIADDRAAVRAKGIELATQLCRDLLDGGAPGLHFMTLNRSPATREIFDQLRADG
LV
>A0A2W5YSA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
SLKARTQFIIGCTFNPNARNLDSQVDRLERKVAAGAQFAMTQPVFDSALVCETKRRTAHL
EIPVFIGVWPLRSARQAEFLHNEVPGIIVPENVRNRMASCGPENESATGLEIARETLGAI
SSEFSGVYLITPFLHYEATCELAQFAREM
>D1BTF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylanimonas cellulosilytica (strain DSM 15894 / CECT 5975 / LMG 20990 / XIL07)|TrEMBL
MVDPTHPRHTANHRPTVSFELMPPRRPDAAPNFWETARRLVAVQPDFVSVTYGAGGGDRA
TARQVVATLLAGTPVLPIAHLTCVGASREDVSEVIDDFLEAGVRAFLALRGDPPKDQPDW
RPPVDGVHSADELVRLLREVESARAAADPSSALRGAAHPLSIAVATFPDGNPAAGTTRAQ
EVQRLLAKQSAGASFAITQLFYEADSYIQFVAEARAAGVTIPILAGLLPTTEPRRLRRVE
ELTGVVAPPDLLDALDALPDAEAQHEYGIARSVELARAVLDAGAPGLHVYTFNKHRPALD
LLAGIGLLERTEQPASVLTPGAV
>A0A252F2K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus porcorum|TrEMBL
MKISDIFQTKKTVFSLEVFPPKKTSKIDTIYDTIERLSDLNPDFISVTYGAGGTGTGSLT
AKIASDLKNIYHIEPLAHLTAIHTTRQQATDILTELRENGIENVLALRGDLHPDLPIPGD
FKYASDLTKFIADFGGFDICGACYPEGHPESEDVISDVTNTRPKVDAGATHLISQLFFDN
NDFYAFQDRAKLAGINVPIEAGIMPVINKAQIERMVSTCGASLPRKFAHMVSRYENDPEA
LFDAGIAYAVDQIIDLIASGVDGIHLYTMNNPRVAHLIYTRIRKVLEASNKA
>A0A2E9V0Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citromicrobium sp|TrEMBL
MEAPLFSGLPGDIEVSFEFFPPKSDKMGETLWQSVETLAPLGPRFASVTXGAGGSTRXRT
HQQVVRIQNEAGIPAAAHLTCVEATREQVDXVARHYWXEGIRHIVALRGDPPDGQSRYSA
HPGGYANAAELIAGLKKVADFEISVAAYPEVHPDSSDRKADLDNLKAKFDAGATRAITQF
FFEPECFFDFRDQAAAAGIKGEIVPGIMPVMSFAAVQRMSGLCGTAIPHWMEGLFEGLDE
RPEARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKA
>A0A399IXY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudopuniceibacterium sediminis|TrEMBL
MTVPAVSFEFFPPKNLEASFKLWDTVQVLSPLAPRFVSVTYGAGGTTRDLTRDAVATLHK
HMGLNTAAHLTCVNATREETLAVADSFAAAGVTELVALRGDPPKGAGAFSVHPGGFANSV
ELVEALADKGKFTIRVGAYPEPHPESPDTAADVAWLKRKFQAGADEAITQFFFETETFLR
FRDDCARAGIDKPVVPGIMPIENWKGMRKFAAGCGAHFPDTLVDAFEKADRDGRADLLAT
ALCTEMCDRLLSEGVENLHFYTLNKPELTRDVCHALGVTPQARFENVA
>A0A1T4VWH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiothrix eikelboomii|TrEMBL
MSEILRRSQLPSFSYADEPTPGENLAILPNHVSPGRLERVLRAGHFAVTTEIAPPDSADP
AEVYTRAKLFDGYVDAMNATDGSGAHCHMSSVGMCSLLTRKGYAMVMQISCRDRNRIAIQ
GDVLGAAAMGVCNILCLSGDGVQSGDHPEAKPVFDLDSMTALNTIRTMRDESRFLSGRKL
TFPPRVFLGGAANPFAPPFDYRPLRLAKKIAAGAQFVQTQYCFDMGMFKTYIQKVRDLGL
HEQVFILLGVGPLASAKTAEWIRSNVAGVHIPDSIISRLKGAQNQKQEGINICIDMINEA
REIQGVHGVHIMAYRQEHNVAEIVERSGALEGRTPWHPGIYESSTTTATQELQPTTP
>A0A1E3R0P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia alimentaria|TrEMBL
MTQLPDSDPTDGGRHPSIVERIATSTTPRVPFSVEFYPPRDEAAEDRLWRAATVFSDLGA
AFVSVTYGAGGSTRDRTVRVVERLVRETDLLPIAHLTAVDHTVAELTDMIRMYGEVGVSN
ILALRGDPPGDPLGEWTAHPEGLHYAEELVRLIHEVGDFHVGVASFPEGHYRARDLEHDS
EILVNKLRAGAEYSITQMFWDVEHYLRLRDRAVAADPEQGAKPIIPGLMPVTSLRQVQRM
VELSGCALPDDLAERLRTAAGDGPEENRAAVREVGIDLTTRMCERLIAEGVPCLHFNTLN
FSKATHEVLTNLSMAPAPGVAAGRI
>A8Q9P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malassezia globosa (strain ATCC MYA-4612 / CBS 7966)|TrEMBL
MSKLGPEFVDITWNAGGRTSDMTTQLVKTVQTYFGVETCMHLTCTNMPRSKIEVALREAK
EFGCRNVLALRGDPPAAGSPWEPHAAGFSHAFELVQYIREHYGDYFSIAVAGFPEGHPEA
VGGPELEMQHLKQKIDAGADFIFTQMFYDLDAFVNWTRRFFHDALDPVKEDDEQVRIVGT
RLVGDMCKKILEHPDLDIHGVHIYTMNLERGSRMLLEYLGLTPSVQQLHPLPWRPSLTPK
RREENIRPIFWANRAKSYIDRTDAWDEFPNGRWGDARSPAYGDADVFGPYLRQTKEEALD
LWGSPTTIQDLQSLFARFCTGELACLPWSDAPLAKETSVINEPLRALNERGFFTINSQPA
VDGARSDDPVHGWGPKHGYVYQKAYLEFFVSPQQLDELIARFDAHPQITYHAVNAQGDMR
TNTTSDAPNAVTWGCFPHCEILQPTIVESMSFLAWKDEAYEIGRRWAAFYEPESPTRRLL
EHVFDTYFLVNVVHNDFKQPNAIFEPFLAASFGTR
>A0A0V0PP38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicyclobacillus tengchongensis|TrEMBL
MAVVGGRYVIFDGAMATYLHQCGVPIRVCAEELNLSKPRLVEQIHRAYVEAGATVVQTNT
FAANRLDLARHGLDAQTVAINEQAVLTARAAVANRASVYGTMGPAAGGTRYGALLTADER
SRLSQVYEEQALALIEAGVDGIVLETFPDLEELLLALRVVRVMAPQLPIVANLSPEEVGV
TRDGVLLTKAFATLREAGASVVGLNCRLGPYGILRSFEQIVFDDGPYAAVPNGGILHRSE
SEGLAYTGDVDDFARVMSDIARLGVRWLGGCCGTTPEHIHKLVLALQAQNSGETWAEPPQ
KPSSIHVVADYRRDEMEGVGAETPLGPSIVDTLKERTAVIVELDPPKHLSATRFLAGATA
LSEAGADMITMADNSLGSVRISNMALASVLKQRGIEPLVHVTCRDRNLIGQQSHLMGLHV
LGVRNILLITGDPSRYGDLPGATSVYDVSSMDLTKMVRKLNDGVGFSGKPLQRPAQFVIG
TAFNPHVHNFAKAVDRLRRKVEAGADFVMTQPVYDPALMEQIAEATRDLGVPILIGIMPL
TSARNAEFIHHQVPGISIPAEVLSRMRETAPEEAQEVGVEIAKSLVDRALTCYRGIYLVT
PFLKFEITVRLTAYIRERTATAVASAARRE
>A0A7X3P0H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MARKNNFIEALAHQILVCDGAIGTELRKRIPSYLQCIDACNISTEHAEKIVAVHRAYVDA
GADVIQTNTYQANKQALAVHGLAEQVEEINRTGVSLARAAAQEHAYVAGSVGQIPLQTLD
TAVPSKKTIRRLFKEQMDALVDAGIDLLVLETFASPKQAEIATKQALTYNVPVIVEISGV
SGGTVGTGLDVRVFAQELEQLGAHAVGINCRGPHDLVEAMELLAPVIKAPIVVQPNAGNP
RVEQGEIAVSYTVEAEVFRDYVSKLIDLGANMIGGCCGTTPTYTAKIRQAVTGRKPVQRE
QRIFVLPQTTSTSKSPTDNPIQQVFETRERIVSVEMRANTFPQLRAMLSEAKNLAAIGVD
LFDVTDNSGAAVNIGAIATAYQLQQATQIPTLIHWTTRSRNLISMQSHLLEAETLGIRGI
VALSGDHPKAGPYETASLVPDVRGAVQLMRLINRLNHGELADGSSIGKPCGFYYGGGFTI
AENLQPHVKHLANKIAQGAKFAYTQPVWTYQDIIRAQQATEHLDIKILYGILPLTSFRSA
SYLRDNLGLYIPQFIVDKFRDLGDTAGHELGMQLSLELVQEIRNQDDTAIDGIYLIPPAR
MNWKNRARVISEIVKTYRDAPLRG
>A0A7C2VTY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
SAVVKMSSWSSCVILKEMGIDPVMQIVVRDRNRLAIQSDVLGAVALGIRNFLCLSGDHPS
LGNHPEAKGVYDLDSIQLIQTLKGMRDEGKFQCGEEISGEVSAFIGAAANPFAAPFELRP
HRLAKKVKAGADFIQTQMIFNVPRFKEFMKQVRDMGLHEKVYILAGVGPIRSLGAAKYMA
TKVPGMDVPEEIIERIRKTPRKNRAKEGIRICVEIIQQIREIEGVSGVHIMAIEWEEAVP
EIVERAGLMPRP
>A0A0C5WJF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium gaetbulicola Gung47|TrEMBL
MGYSYASHLDSLNQNIADIDGNINVSFEFFPPSSEQMEQTLWNSIHRLKTLQPKFVSVTY
GANSGERDRTHSIIKDIKEQTGLVAAPHLTCIDATRDELRSIARDYWNNGIRDIVALRGD
LPAQGVKPDMYAADLVELLRSEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGACRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNMKQAKRFANANNVKIPGWLEKQYE
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAKA
>A0A2T5BD58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. VMFN-G11Ma|TrEMBL
MGAAGLGALLGSVRYEVLPARATEEKVLAHVPRDVAITVTASPVKGLEPTLDLTGRLTAH
GYRVVPHVPARLLRDDVHLKEVVERLRGAGVDDVFVPAGDADPPAGPYDGALPVLRRLSE
LGKPFARVGITGYPESHPLLHDDLTVQAMWDKQAHADYIVSNLCFDPRVLDEWIARIRRR
GVTLPLYVGVAGPVQRAKLLAVATKIGVGESTRFLTRHASWFWRFAAPGGYAPERFLSRS
ERALTAPSAGVAGLHLFTFNQIAETERWRRALLARLGALSP
>A0A4U8SUS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. MIT 03-1614|TrEMBL
MYDIESLIEQIHSTEPFLSVEIAPSISGRLDENLLEDLKTLKLAHAFVCTDSPLARFKPS
SILSSLKFQNALQKPVICTISMRDRNSIALCGDILSVNELGLRTFLTLTGDSIKNGDCLQ
SKGVFEDNSLKLGHIIDELNCGRALNGKSLKENIKRIYNFQVINAYANNPLSLKNKMRKK
LSSCEIYALFTQPVYSLNAAEFLLQSLEEIKSECNIKSALVLGFFPVLSYKTALFLRDKL
PGVYIPNEWVQKLEKAHNKGKDEENKVGLEISHSLFMELKSVHNKFHFMSANKPSLVKEF
A
>A0A5M8QH34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rufibacter glacialis|TrEMBL
MKVTEHLKNATNTLFSFEILPPVKGTSIQSIYQGIDPLMEFNPPFINVTYHREEYVFKER
ENGLLEKITIRKRPGTVGICSAIMNKYHVDTVPHIICGGFSKEDTENALMDLNFLGIDNV
LLLRGDAVKTEPGFRPHKDGHAHASDLIQQVVQLNHGHYLDEEMENPVPTDFCIGVAGYP
EKHVEAPNLGTDLKYLKHKVDLGAEYIITQMFFDNEKFCDFVKACRAAGINVPILPGLKP
ITAKSQLTVLPRYFNIDLPEDLVTAVEACKTSADVKQVGIEWTIQQCKELVEFGVPCLHF
YTMSKSEATAAVARAIF
>A0A5B6ZG58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Davidia involucrata|TrEMBL
MGWTTCSRGWRGWWPTTLHSAXTADLTLEIANRMQNMVCVESMMHLTCTNMPVEKIDHAL
DTIKSNGIQNVLALRGDPPHGQDKFVQTQGGFACALDLVKHIRSKYGDYFGVTVAGYPEA
HPDVIQSNGVATLEGYQNDLAYLKRKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCP
IVPGIMPINNYKGFIRMTGFCKTKIPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKIMA
NGIKTLHLYTLNMEKSALAILMNLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRP
KSYISRTIGWDQYPHGRWGDSRNASYGALSDYQFMRPRARGKKVHQEWAVPLKNIDEIHE
IFKKYCLGNLRSSPWSELDGLQPETKIINEQLGSINLKGFLTVNSQPAVNGAKSDSPSVG
WGGPGGYVYQKAYVEFFCSREKLNALVEKCKAFPSLTYMAVDKEGSWISNISQNDVNAVT
WGVFPAKEVFQPTVVDPSSFMVWKDEAFEIWSRGWAQLYPEGDPSRKLLEEVRCSYFLVS
LVDNDYIHGDLFAVFKDF
>A0A1F0UK88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus sp. HMSC073C03|TrEMBL
MSYANEINTLNQHLADTNKKINVSFEFFPPKNEKMESMLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGIEAAPHLTGIDATPEELKEIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIEAEIVPGILPVTNFKQLQKMASFTNVKIPAWLSKAYEGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHTLGIRPTTNP
>A0A2D5W1F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedosphaera sp|TrEMBL
MRQIRDIHQQRKSEGKPAFSFEFFPPKTEKGEEALFGSVLPELQTMAPDYCSVTYGAGGS
TRDKTLDMVERIQKDFGLVCMSHLTCVQATKEQIAQVLQDAEKRNIRNILALRGDPPGGV
GPFEATEGGFAYSKDLVAFIRAHHEMSIGVAGFPEGHIACKEGKEIDWGRLKEKVDAGAD
FVVTQLFFDNEDFLRFRDHMVKELGMHQTLIPGILPVLSTRQIQRFTELCGASIPTPMMQ
RLEDLSEDDAAAAAFGIEYAVGQCEELLKEGVAGLHFYCLNKAHSTLEVVRALASHR
>I6Z779|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melioribacter roseus (strain JCM 17771 / P3M-2)|TrEMBL
MLKQINRDKMKVIEHLEKSNDTLISFEIIPPKRGGDIKELLNVLDDIVKYNPPFIDITSH
PAEVVYEETPGGEIKMKVKRKRPGTLGICALIQNKYNIDAVPHVLCTGFTKEETEDFLIE
LHYLQIDNVLAIRGDDNGFRKPLKFGRSVNEYAVDLIKQINDLNKGKYLEDGLLDAEPMD
FCIGTSGYPEKHFEAPNLISDIKYTKAKIDAGASYIVTQMFYDNKYYFDYVKLCRQEGID
APIIPGLKIITSKKHAYTLPKNFFIDIPTELADELEAAKPEHALDIGINWAYKQVEELLN
NNVPAIHFYIMQNSRPIKLLMKKLGY
>A8UU31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenivirga sp. 128-5-R1-1|TrEMBL
MKIGEIFKKGIFSVSFEFFPPKGEEGERQLFQTIKELEELKPTFVSVTYGAGGSTRDRTR
NVVKRIHEEVGLTVMAHLTCIAHTREELIEILEDYRGIGIENILALRGDVPHDTPDFRPP
EGACSYAKELVELIRERFGDYFSVGVASYPEGHPESPNMEWEIRFFKEKVEAGADFSITQ
MFFENRYYYEFVELCLKAGIEIPIIPGIMPITNFKQIKKFASMCGATIPQSLIEKMEPVE
DKPEEVAKIGVEFAVKQCEDLLRNGVPGLHFYTLNRSKATLNIYSAIKDLVPVRDLYA
>A0A1V9EHZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niastella populi|TrEMBL
MKVIDHIRQATGSLISFEILPPLKGKTINSIYEHLDPLMEFKPSFINVTYHRSEHVFKKK
ADSTFEKVEVRKRPGTVGICAALMNHYRVDAVPHLICGGFTKRETEDALIDLNFIGVDNV
LVLRGDAAKNETVFEPEPGGNAYAFDLLKQVVNLNNGIYLEEDIRDGFKTDFCIGVAGYP
EKHFEAPNLQTDLAFLKAKVAAGADYIVTQMFFDNQKYFDFVKKCRDNDINIPIIPGLKP
ITSKKQLSVIPRTFHVDIPDDLSNEIMNCKSDADVERVGTEWLLLQSKELKKAGAPVLHY
YTLGKPKVIYNVVKQIV
>A0A1Y5Q9U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Stenotrophomonas sp|TrEMBL
MTALSFEFYPPKTDDQRAQLDRAANKLKVHAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLQAAPHLSCVGGTREEIRELLKLYRAIGVKRIVALRGDLPSGMGFPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLRHFKAKVDAGADAAITQYFYNADAYFRFVDD
VRRLGVDIPVIPGVMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAESVRAFGADVV
AALCERLSAGGAPSLHFYTLNLAKPTSAVLQRLGRA
>A0A837X6I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas europaea|TrEMBL
MQSQKKFTPTFSFEFFPPQTPEGMEKLRATRIQLAQFNPKFFSVTFGAGGSTRERTLETV
LEIQAEGYPVAPHLSCIGSTRDNIRSILEKYHSHGISRIVALRGDLPSGMAQAGEFRYAN
ELVAFIRKEFGDTFWIEVAAYPEYHPQARSALEDFTNFRRKVEAGANAAITQFFYNVDAY
LHFVEMCEAADLNIPIVPGIMPISKFSQLARFSDGCGAEIPRWIRRKLESFGDDIPSIQA
FGLDVVTALCARLLEAGAPGLHFYTLNSAVLPT
>A0A833M7C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiaceae bacterium|TrEMBL
MTNAHPFHIDENPAGPHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RARIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRVMRDYGKFLSGRKLTTPPQ
LFLGAAVNPFAPPHDFRAMHLAKKIAAGAQFVQSQYCFDVPMLKTFMERVRDLGLADKVF
ILVGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPG
VAGIHVMAYRQEEYVAEIVDESGVLKGRRPWKREARRDDRLVADRLGHILKDDVTESQVD
MVKSAH
>A0A7T3MMJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTNRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQVALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1T2P7Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIQKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARVLKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A841QH00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter lovaniensis|TrEMBL
MSLNRLCVELIPRSADSLEQDVKTVQTVFPAADTLNVPDLMRFPLRSWDAAALLRPVFPR
VIPHIRAIDIAPHAPLPGAGQDGLEEILVVHGDPPADLSMRTYPNSTESIIRRYRKEAPH
LNVYAAFDPYRRAPWKELEDVARKKEAGACGFFTQPVFDYKLFDLCREWLQGENVFWGLS
PVIGPRSRSYWETTNHIVFPKDFSTTLESNIAFAQTVLRELGQDKGSAYLMPVRVKLEHY
LPALLDAVA
>A0A7S4CBP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eutreptiella gymnastica|TrEMBL
LDICSNCQNLFCLDTMVHIGWRHTEHTTLATILKEVKTNGIQNILARNDDETRPEVTAQL
IRNIRALHGDYFCIATVAYPEGCRHGASEEEEMRDLKAMVDAGCDFV
>A0A7C5VUL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomicrobium roseum|TrEMBL
MAHPFLERLQRGPLLADGAMGTQLYERGVRPEQCFEAMNLREPDLVVAIHRDYILAGAEL
IETNSFGANRMKLESHGLGERVREVNRRAVRLAREAREITGIPVLIAGAVGPSGRILAPI
GTVAPETIRDVFREQIEALLEGGVDLLIFETFSQLEELRQAILAAREVSDLPLVAQMTFA
ADGRTMAGHTPDVVVQSLTELGVDAIGVNCSVGPRSMLAVLRDMVAANTGNIPLSAMPNA
GWPTVLGDRVIFGSSPDYFAEFAQEALELGVRILGGCCGTTPNHIAAMRRVLDEQRGTSV
SSGAAIRLEERVRPVIVLAPEGPTRLKQKLGREFIISVEIDPPKGLNPQKAIDGARILRQ
SGVEFINVADSPMARVRLSALGLCYLLQHEVGIETILHLTTRDRNLMGLQSDLLGAHALG
VRNILALTGDPPTFGDYPHATPVYDVDSIGLVRILTNFNNGMDAGGASIGQQASFTIGVA
CDPTRPDLDRELERLHAKLAAGAHFIMTQPVFDLDTWLTFVRKYEERYGSLGVPVLLGIL
PLQSYRHAVFLHNEVPGITLTEEALERMRRAGANGRAEGVAMARELVARAYEVVEGIYIM
PSFGRYEVAVEVVESLPQNRVRRVTS
>A0A8J8SDL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vallitalea guaymasensis|TrEMBL
MQLRDYLKNSILVTDGAMGTYYSKKTLKDTTVSELANINDKKIIETIHKEYIEAGAKLIR
TNTFSANTVSLKCSRIELRKIITEGYNIAVDSAKGKDVFVGASIGPIPEKLESEKDDILD
EYYCIINTLLDLGADIFIFETFASTNYIKILAAYILSKNEKAEIIAQFKVNAFGYSKEGI
SARRLIEEARGIEGLVAYGFNCGIGVGHLYKIIRNLDIEDENIVAIPNAGYPDKIYARTV
YRDNARYFGETMVDIKKLGVKVIGGCCGTTPSHIEEIIENLEGNYEPSSIYHRNKTQKKK
GISNTPNRFYKKLMNKEFVFAVELDPPYNGNIQKTMEGANILKAEGVDIITIADSPLSRP
RADSIIIANKIAKEVGIDVMPHICCRDKNVIALKSIILGAHIEKIRNILLVTGDPIPSEE
RIETASVFNVNSIKLMELVKELNVDFDPEDAMIYGGALNPNLTYVDKIIKRINKKQEAGA
KYLLTQPIYNDQAINNLKIIKENTDIKILGGIMPLVSYKNARFLNNEIAGIDIPENICSM
FTKDMTREEAENVGIEIAVEIAMKIKDIVDGIYMMTPFNRVEMVSKIIKSIR
>A0A6G3VZ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID9944|TrEMBL
MNPLSTARTAVGALLLEDFSLEMTGKDVAKLEEARETIPQGTRINITFLGNEDLRMRLEA
SRAVKRLGFVPVPHLSARRLGSRAEFAEFLAALRAEGACDNVFAVGGDPARPKGPYEDSL
ALIESGLLQEHGVRHVGISGYPEGHPDIAADVLRTALRDKSAALRARRLDGGVITQFCFD
VDPVLAWLAQLREQGITLPVRIGVPGPAGVRRLMSYAARFGVGTSASIAKKYGLSITNLM
GTAGPDRFLHALAEGYDPARHGDIKIHFYTFGGLRATSEWIARFRKEHHV
>A0A1G4QTR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas peli|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVKVPTAPHLSCVGDSKAELRELLNLYKSSGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADCYFY
FVDRVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTDSIQAYG
EQVITEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A6B9F8B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloplanus rallus|TrEMBL
MPFDSFEGQMERLPDGAEIAVTASPQLGLDATVEWSERAAARGYDPIPHVAARYVRDGDH
LDEVAGRLADAGISDIFVPGGDREDPIGEFESAHDLLVALEDLGYAFEEVGITGYPEGHD
FLDDRTLAEAMERKAPHATYLTTQLCYDPEAVRRWIETVRDRGIDLPVEVGIPGVMKYQR
LLSISQKVGVGDSVRFLRKTSGIVGFVRQLVGSRGKYTPDDLVDGLAPYAADPDYGIRGL
HIYTFNQVDDTETWRRSRIDG
>A0A0J7D6R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGSATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6L3WGA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAEALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNGGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A150E8J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVMPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0V1IBY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella pseudospiralis|TrEMBL
MAIILQSALLVCISVYCLMIFFYSNNYVVFFPILCYPTGHPDASSYEEDLLNLKAKVDAG
ADFIITQLFFDEMHYFKFVNDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSKIVIPDSVL
TTLESIKENAEAVRNFGISFAVELCRKSILEQIGLWKESPVRMLPWKKHPVHSVRCREAV
RPIYWNTRPKSYLCRTRDWKQFPHGRWGDLGNPAFGDLKHYLFSCIDQMNDSCALDMWDK
ELSSFEHVRDIFCNFIARTPNRHGHTVRRLPWNENHSDPAVDVLKDELIYYNSNGILTIN
CQVAVNGLPSNDPIFGWGEANGYIYQKVDDAQCILISLGSFETLNYDEDATMALTWGVFV
GQEILQPIVANAASFRVWKDEAFDLWQRWARLYESGSIGRKLLQSIHDDHRLITLIDNDY
PQPCSLSALLRAVIDECCEEKKIDDE
>A0A532UTF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium B3_Pla|TrEMBL
MKVTNLWSAGQKPTVSFELFPPRSLKGAEKLEKTIDELAALRPDFVSVTFGAGGSTREGS
RQLVEKLKNEKMLEVVAYFAGYGLSPEDIVAVLDDYQALDAENVLVVHGDIPRVQEDFEP
DPQSFPHASDLIAFVRPKYDFCLGAAGYPEGHIDCESKDKDLEYLKLKVENGADYIIANY
FYDNKYFFDFVQRCRAIGIDVPIVAGVMPIYSVKMTEMLTGLCGATITDEVREGMASLPE
DDNEALVSFGIDFAVSQCRELIETGVQGLHFFTMDQSKSMVGIVNRLRDDELL
>A0A524HIN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MLMANNPPCSRLEEVLRAGHFAVTAELNPPDSADPEDVYQAARVLAEVTDGINAVDASGA
NCHISSVAMCALLTRAGYEPVYQVTCRDRNRIAIQGDMLGAAAMGVLNVLCLTGDDVSAG
DQPEAKRVFDFDSIQLLRTARMMRDEGVFLSGRKITTPPCFFLGAAANPFVPPYDWRPQR
LAKKIAAGAQFIQTQYCYDLARFKEYMTRVRDLGLDKQAYILAGVGPLKSAGAAEFMRTK
VPGVVIPDEIVERLRKTPREKQQEEGKQICIELIQLLREIEGVAGVHIMAYRQEELVADI
VKQAGLFPRPK
>A0A1Q4FWI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium 69-70|TrEMBL
MPATAPSRLPIPVSLEFFPPKTDEQRETLEKALPALKALNPEYVSVTFGAGGSTLSYTPD
TVCHLREQHGLDSAPHLSCMGGTRAEIRSLLQLYRSKGCRRIVALRGDLPSGMASYGDFR
YASDLVGFIRDETGDFFHIEVAGYPEVHPQSDDAQADLIHFKRKVEAGANGVITQYFYNA
DAYFRFVDDARRLGVNVPIVPGIMPITNYSQLRRFSELCGAEIPRWVARRLQSFGDDHEA
IREFGADVVTALCRRLVDGGAPALHFYTLNRARATTAVVERLQA
>A0A523YY56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MLAGMCGATITDEVRQGIAALAEGDKEALVAFGIEFAFRQCAELLEAGVPGLHIYTMDRS
KSAVGVVDRLRDEGLL
>A0A135UX71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum salicis|TrEMBL
MHIKAMLDESQRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREHEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDEGATF
IVTQMFYDGDNFVRWVGKVRERGITVPIIPGIMPIATYSSFLRRAKHMNCKVPEEWMKAL
EPIKNDDVAVREVGKGLVAEMCRKIVAAGIHHLHFYTMNLAQATRMVLEELEWMPTSDRP
VKHALPWKQSLAHGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSVKDIANIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSTHPVHGWGPANGYVYQKAYLELLVHPDVYHEIVARVEKNP
DMTYYATTKNGNLKYNASNDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGIDW
AHCFEAGSPSRTLVERIMNDWYLINIVNNDFHQKTALFDLLEGLEVKEYSDIPAEPQTNG
AAKEQQTNGSAPAAVAAN
>A0A542GN31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. SLBN-112|TrEMBL
MSPPSLIDAHPNLSDTAPVALSYELFPPRSPAAAETLWTTIRELEATEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIVGELLDTGVRGILALRGDLPKD
ASAPASGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEEHDVEVLL
AKQRSGADFAITQVFFETRQYADLLTRARRAGVTIPIIPGVMPLTSLRRLNRLGELTGVE
PAPQLMSRLAAADTDAERLRIGVDATVDLANAALDAGAPGIHIYTFNEHQSALEVLDKLA
LPRRCRPGIRRESSARGQLAS
>A0A7C0UUS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSELKSVLESGGFAVTSEVAPPKGVDLSGCLAEAEQLRGKVVAINVTDLQSAVMRVGSLA
VCAKLVEKGLEPVYQLTCRDRNRLALQSDLLSAWALGIENVLCLTGDHPFLGDHREAKPV
YDLDSVQLLKVASGLNDGTDMAGHELEGKPNFYLGAVVTPTADPLEPQLIKMEKKIDAGA
RFFQTQAIFDPEAFEKFIEHTKGFGVPIIAGIVVLKSAAMAKFMNENVAGIHVPDSLIQE
MADTKKEDRKKKAVEIAARIIKAVKPMCQGVHIMPLGWGDLVPDIIDAAELS
>A0A7I0KG24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M8A.F.Ca.ET.167.01.1.1|TrEMBL
MTGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHEDITETQVDMVK
TAH
>A0A223GIC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia pseudosolanacearum|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILDTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRKEMNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>A0A7D8Z1B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vanrija humicola|TrEMBL
MKITEKLAKAEREGRPFWSFEYFPPRTAQGLQNLYDRIERMRLLGPEFIDITWGAGGKNA
DLTSSLVQVCQESIGIETCMHLTCTEMPQDKVEWALQQAKQFGCQNILAMRGDPPAGASK
WEPTPGGFAYAVDLVRYIHKHYPGDFCVAVAGFPQGHPETPNTEEGRHQEMLWLKEKVDA
GADFIFTQMFYDVDILFDWVKRVRSYGITVPIIPGIMPIQNWGKFQTWVQRESIVVPDHF
YEALNPVVGDDEQVRAVGTKLVADMCRKILANEECGIKGLHVYTLNLEKGARMLLEELNF
ESRREQVAPLPWRPSLTPHRRQETIRPIFWANRVQSYLSRTADWDEFPNGRWGDSRSPAY
GDLDGYPVQIGITAEQAQKLWGNPTSVDDIAELFAGFCRGTVEKLPWSSSPPASETSVIT
EQLARMNQHGYLTINSQPAVDGARSDDKVHGWGPAGGYVYQKAYLEFFVSPELLEPLIRR
IEGDSRFTYHAVSKTGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVETVSFMAWKDEAFE
LGSLWANLYPEGSETRKLIEDVMANSYLVNIVANNFKDSTAIFEPFLLDQPATNGKANGA
ANGH
>A0A7D8EEW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klenkia terrae|TrEMBL
VTGTVRDLIDEGRPTWSFEFFPPKDEAGAAQLWTTLRELERLAPSFVSVTYGAGGSTREG
TLAVTEQIATDTTMLPLAHLTAVDHSVAELRNVVSRLAAAGVRNVMALRGDPPGADPQAD
WVAHPDGLQYAAELVELVKSMGDFGVGVAAFPESHPRSPDPDTDVDMFVAKCRAGADFAI
TQMFFRVDDYLRLRDRVAARGCDVPVLAGVMPVTSAKQIARIVQLSGQAFPGELAERFDA
VADQPAAVQRALGVDVATDMCAQLLAEGVPGIHFITMNRSTATREVYSRLVPVNAV
>A0A7C3AGU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTMATSFRDALNSGKFVITSEIGPPKGTNLEKMYHHIDLLKDKVDAMNVTDHQSSVMRFP
SIGGCLAIKEHGGEPILQMTCRDRNRLALQAELLLAYTRGIRNVLCLTGDAVPVGDHKEA
KGVFDLDSVQLLRTIRQLESGKDLGENDLDGAVEFCAGAIVTPEATPIAPQLVKFEKKIE
AGAEFFQTQAIYDLDNFGKFMQYARQFPVKVLAGIVLLVSARMAKYMTENVPGIFVPQNL
IDELVAAPKGEVLNKGIEIAGRMIAALKNDSTCDGVHVMAIGREEVVPDILAAAGL
>A0A7D4B0L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp. BRD128|TrEMBL
MKVTEHLRRAEGKTLFSFEVLPPRKGENIHSLFSNIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRKRPGTVGICAAIKNRFDVDTVPHLICGGFAREETENALIDLHFLGIDN
VLALRGDPIKSEGHFQPHPDGHTYACDLIGQIDSLNHGRYHDHDEQYQPEGSEPVLCTDF
CIGTAGYPEKHFEAPNHGSDIRFLKQKIDRGADYIVTQMFFDNEEFFKFEKRCRDAGITV
PIIPGLKPLTTKAQITALPRAFFLSIPEALAEAIHQAKDNAAAREVGIEWCLNQSRELMA
HGVPCLHYYSMGKAEAIRRVAAGLF
>A0A7V2PM55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIGELIKKHGSSLSFEFFPPKDETAEAKLFQTVAQLKSFKPTFVSVTYGAGGGAMKNTR
HIILRLKRETPLTAMPHLTCVDQSMDELAKILGDYKEHGIDNVLALRGDPPKGAKEFVAP
KNGFCYATDLVKLAVSIGGYSIGVAVYPEGHIEAPSLEMDMHYTKQKIDAGADFAITQMF
FDNHFFYDFLERAEKAGIAIPIIPGILPITDFERITKFSQKSGATMPDHIARRFSRAGAS
PEEAEKIAIEVATEQCADLLENGISYFHFYTLNQSRAVTAVVNNLSLERLGLKISPAGE
>A0A7X8AUC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp|TrEMBL
MKLIELFKTKKPVISFEIFPPKLDMPIESIYDKLEDFKKLNPDYISVTYGAGGSAKDRTI
EIASKIKKDYHIESMAHFTCVGHSKEEIDSLIDSLENQGLENVLALRGDPPRDQPDFDFS
KNVYQYASQLIEHIKKRSNLCIAAAAYAEGHVDSHRIKDDLINLKNKVDTGVDFLVTQLF
FDNRIFYDFLDRAISLGITCPVTPGIMPVFRADQIKRIASLCGASIPAELVIVMDKYGDN
PDDMLKAGIEYACNQMQDLIDNGVDGIHLLTMNRAKSTRKILENLNLLKK
>A0A7C7YC45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MEAAGSTSHNLRNMLENSDRFLTAVEIETSRGLLMAEASRRTAELAKRLSEFDKVDFVSL
TDNPGGNPHIRPEVLGQDLLFRGCDVVINMSCKDYNRNGVESRLWALGSQGFSNVLALSG
DYPIGGFQGQAQPVFDIDSVGLLELMSKMNDGLPNQMWGSVGREDRLEKTNFFAGCAVSP
FKKLEGELMTQYFKLALKVKTGAKFAITQIGYDSRKAAELYQYVQSNDINIPLIGSVFIL
TAPAGRFFNNWGVPGVWVSDELRDEANKKAKSKDRGKAFFSELAAKQIAILKGIGYRGAY
ISGRPQLKRMQGILEMADSFGENDWKDFAKEINFAQPDEFYYYEQGDNPGLSSNEVNPSY
RASKSKSARAKAQVTVPLQFRVGKFVHDRVFTEGTVGFKVGKAVYSQVEKSKKLSKIAHI
AEQATKVPAYQCRDCGDCSLPDIAYLCPESQCVKSQRNGPCGGTKAGKCEILDQECIWIR
AYDRLKPFGDETKMLQRPIVFRDASLRNTSAWANTFLARDHHANRNPEDTDSRA
>J6EUJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichosporon asahii var. asahii (strain ATCC 90039 / CBS 2479 / JCM 2466 / KCTC 7840 / NBRC 103889/ NCYC 2677 / UAMH 7654)|TrEMBL
MTHLTALIESQKGPVHTYEFFPPRTEQGFTNLLDRIRRLTLPPLRPPVAVSVTWGAGGST
SDRSLELADAITKMGVEVILHLTCTNMPKEKVDTALAELGITNILALRGDAPRSDEYATD
ADANMDEFQHADDLVRYIRKQYGDYFCIGVAGYPTPHPDSLDADDDLKWLKEKCDAGADY
IITQLFYDVPAFADWVQRCRQAGIAQPIIPGIMPIQSYSSFRRLINLTKCTVPDYIMQEL
EPIKTNDAAVKQYGASLATEMVKKLMASKLVPGVHFCTLNLEKSVRTILENLQWNSKKVH
DSIHSSPVSRHNQLISEEALEMDDGEEKVPLAVSAADVAQWVKNTREHTAVGGEPSWDEF
PNGRFTDVRSPAYGEIDGWGNGLKITPAQALKEWGTPATFEDLSDMFTRYLRSDPGTPTT
PFCDMPLSPESQTILDSLIALNAPDKRYWTVGSQPAVDAARSEDPVHGWGPPGGYVFQKA
YVEFFVPKSEVERLEKKLAGEKSTLFSMYAANRQGDTAGNTDKESVNAVTWAAFPGQEIV
QSTIIEELSFLAWKEEAFEIWDEWARLYPRNSPARKLIENVSDEWWLVCLIHHNYKDTEG
LWRFLLDN
>A0A2W4S387|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTCKDTEFLAEAATLVPKNTDIFIALFPNQTWDDLKVAAKAVRDAGLNPVPHVPARRVKD
RNEVAEIARKLTQEAGATRMLLIAGDMPKPEGAFDSTIGVLETGELTKAGIRTIYMAGHP
EGHAHMTVEQQRHFERRKVELSKEFGFELKFTTQVCFEAEPIIEWERVMRGNGITNTIRP
GLGGPASIKTLLRYAKICGAGASIRALTSGKASLIAGLLKDSGPEEVVNKLAVANASGQT
SFESVHLFAFGGFLKTTKWVSAVQNGRFEINPRDGDFSVQM
>A0A351JY07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MANRSFKEALDSGDFVVTSEVGPPKGTNIEEMLHHIDLLKDKVDGINATDNQSSVMRISS
LAVCHLAQERGAEAILQLTCRDRNRMALESELLSANILGVHNVLCLTGDYVSVGDHPDAR
PVFDLDSVHLIQTVRTMEQGKDIAGNELNGAIRFCVGAIVTPEANPIEPQLLKFEKKIRA
GIDFVQTQAVYDVDNFRKFMQYARRFKVKILAGIILLTGAGMARYMNANVPGVVVPDELI
RELAGAPKGQALQTGIAIAGRMIKQIKDENICDGVHIMAIGREGLVPQILETAGL
>A0A2G2AST9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp|TrEMBL
MFDTLIDKLRNNTFITLETTPGHSPQFTPIVDKIDSLGLQNLVDGFSTTDNPLAKLKYNA
LFAAKILQERFNKPVIATMSMRDRNKIALQSDLLGANEVNIRAILALTGDPASISDQPHT
KGVFESDSSLLLDIISAFNSGMNYAGKPFTHKPQNIFPFAVVNSYAKNPKTLQKKMQKKI
RHGALGIMTQPVYDIENAKNLIDLNEAANAACSPEYKRAELILGVFPITKLRTAQFLSAH
VPGIHVPESWIDKLRVANTHSPEEEYKVGFELSKNLFDTLKEEHPKIHLMTANQFQLAHD
ILV
>A0A2G9ZTZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium CG23_combo_of_CG06-09_8_20_14_all_52_9|TrEMBL
MKTEPISNLERVLSEGRFAVTAECGPPRGANAEVIRKKGALLKEVVDAVNVTDNQTAIVR
MSSISSCAHLLALGIEPVMQMVTRDRNRIALQSDILGAYSLGIQNILCLSGDHQRFGSQP
DSLNVFDIDSMNLVRTVYTMREEGTDMSGHLLDGSPRMYIGAAANPFADPFEYRVIRLAK
KIDAGADFIQTQCVYNLERFRQWMSMASGEGLTEKVHILAGVTPIKSAGMARYMAKNVAG
MDVPESIIRRMSQVPKEKAAEEGIAICLETVAALQEIPGVHGIHIMAIEWEEQVKIIVER
AGLLPRP
>A0A2D9LY01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSKIPDLAGNGSSCLKIICDFSPPRGGMPSLIGDLDGLNPDIVSVAYNPGKSVRVNPVAA
AAWIKANTKQDVVFTLGTRDMNKVAIQSLLLGAQLLVLQNIVIVEGDGLSNRDRERFKAV
YDFQPTSLIESVRDMNQGKDFRGLKLRVATDFSVGATIDMGRPSDSEIPLAVRKAQAGGK
FFLAQAEFDPSVIARFRADFESHFDKGHAPPVFYGVQILAKDGIIFGNVPQRTRSELESG
RSGEEIALELIQNLMVQGVRTVYLVPPIFRGGRRDYDSARRVIESARRLAS
>T0UAM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HSISS1|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFKYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSGLLTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHEATHSLFKHHSQVSAL
>A0A164MY20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia terpenica|TrEMBL
MGRLGPRPDGTIPFSVEFNPPRDAANEARLWRAAREFERMHPAFVSMTYGAGGSTRDRTA
RVTGQLARETTLLTVAHLTAVGHSVAELRSIMGTYADSGIRNLLVLRGDPPGDPLGEWQR
HPEGLEYAEELVRLVRGLGDFHVGVASFPQGHHRSPDLDHDTAHLCAKLRAGAEYSITQM
FFDVDDYLRLRDRVIACDPIEGAKPIIPELMPITSLRTVQRAEELSGRPLPTRLRERLER
AGGADPDANRAAVREVGIEIATEIAQRLIAEGAPCLHFITLNFAKATSEVLTNLGYTVTA
APVGA
>A0A419GLI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gaiellales bacterium|TrEMBL
MKSGSILEKTLESGAFAVTGELGPPKGADAGVITRKANILKGHVDAVNITDNQTAISRMA
SMAAAKIALDEGLEPIMQMTCRDRNRLAMQADILGAAALGIRNLLCLTGDHQSFGNHPDA
MGVFDLDSVTLIRMVKDMRDVPAFQCGEEITKAPELYIGAAANPYADPFPFRAIRLAKKV
DAGIDFCQTQIIFNVDKFDQFMAQCRELGVTERCRILAGVAPLKSAGMAKYMKNRVAGMD
VPEEVISRMEGAADAQDEGIQVCVDVIDRVREIEGVAGVHIMAVEWEEAVPEIVSRAGLR
PGSARS
>A0A4U6MWX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. NamB2|TrEMBL
MTPHDRAAIPPSLSYELYPPATPEAGDSLFHTIDELSATTPDYVSVTFSGTPGRRRASVG
LIKHLVRNTRLRPLAHLTCVGETRESLDRLVREFLGLGVRGLLALRGDLPRDPEVPSGEV
SFAHQLVELIRDVEARHGATLAGGKLAVGVAAYPNRHPESPSFLHDVEVLVSKQRAGADF
AITQVYFDPAHYAALVVAARAAGVTIPIIPGVMPMANVRRLERLAMMTGVRPDAALLHRL
ETASDDGERRRIGVRAAAVLARAAFDAGAPGLHLYTFNDHRASVEVIDQLDLPAARSLAV
PA
>A0A164RQH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sistotremastrum niveocremeum HHB9708|TrEMBL
MKITEKIEQANKEGRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITCRPIDARN
AGGRTSDLTSELVKTCQSLIGIETCMHLTCTNMPKEKVDNALRDAKAHGCRNILALRGDP
PAGKEEWESVEGGFEHGIDLVKHIRKNYGDYFDIAVAGFPQTQTLPPAERDLEMKYLKEK
IDAGVNFIFTQMFYDVDMFIDWVKAVRAAGIAVPIVPGINPIQTWNGFMRATSLAKTIIP
PKFLQALEPHKNNDEKVREIGTKMVADICRRIIAEDVGIRGLHFYTMNLEKGTKMLLEEL
EFVARVQTIKPLPWRQCLTPTRRTETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSP
AYGELDGYGVWLKQSKEEAHALWGHPTSYAQIARLFSKFCTKEISALPWSDEPPSAEMSV
ISSQLGRMNELGFLTINSQPAVNGVRSDHPVHGWGPSKGYVYQKAYLEFFASPALLSTLL
PYISRDSNITYYAINKHGDLRTNSHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEA
FELGMQWANLYEPGSASRSLITDMMENYFLVNVVHNDFQDTEAIFRPFWAVAAEAGLEQP
EIQRLSNGVRQLEVASVA
>R6JZK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium clostridioforme CAG:132|TrEMBL
MDDAEGRERRLKIREILAVGKPTLSFEVFPPKTEDAYDSVEKAAAKIAKLKPSFMSVTYG
AGGGTSDYTVGIASAIKEEYGVTPLAHLTCVSSTREKVHHVLGELKERGIENVLALRGDI
PQDGSTPKEYHYASELIREIKKAGDFCIGAACYPEGHVESANKSVDMDYLKQKVEAGCDF
VTTQMFFDNSILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTCLPSRFMSIV
DRFGDNPAAMKQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A2W4MA90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MQQSSQEISAPADKEGVQETIARLAREATIEINVQDEKYLAESREYLQPGTRVFVAHLPK
QSWEDTVAVCRTVRDMGYDATPHVPVRLLDSEATLDNVLAAFAREKIQRLLLISGDYPEA
AGPYSTVSQVLRSGLLQKHGLKKVSVAGHPEGHPKVDLAEVRRSEREKAALGGPDLEVTL
VTQFFFEHEPFVEWVRELRAEGVRNDIYGGLAGPANLSTLFRFAMRCGAGPSIRALGARP
TSLTKLIGERGPENVMRGLAEAHVAGTAEFTGVHFFCFGGFLRTCKWVHAVANGRFKLNA
SGGFDVA
>A0A6G2FXA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halogeometricum sp. CBA1124|TrEMBL
MSLSTRTVSHPEGVETLLTDARFELMPFESFDDEITQLPDGATIAITTSPQLGIERTVER
TEEARARGYEVVPHIAARYVEDRDHLADIVDRLHDAGVTDIFVPGGDREEPAGEFESAYD
LLSALDEMGRSFEDVGITGYPEGHDFLDDETLWESMERKEPYATYIVTQLCYDPETVVEW
IEDVRARGVELPVEVGIPGVMKYQKLLKISQKVGVGDSIKFLKKTTGILGFVRQLVGSRG
TYKPDDLVDGLAPYVGDDTYRIRGLHIYTFNQTSDTESWRYGRLDD
>A0A8H6BXE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida albicans|TrEMBL
MSTVAERIASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTS
EKSLDLAATCQNEIGITTVLHLTCTNTNKEVIDQALSKAKAAGVRNILALRGDPPRTEEY
WTPNCDFNGAVDLVKYIREKYGDYFCIGVAAYPEGHVDGSDTSSQNPQRDIPFLVEKVKA
GADFIITQLFFDVEKFIAFDKLLKEHDELKGIPLIPGLMPITTYKVFNRAAKLSHASIPK
EILKQVDQVCHDDNAVKALGVDILSEMIDQIDKSTTIKGYHFYTLNLEKAVASILDKSDV
LRQILEGPSYATRFEDAVASDSDDEDEPEKASERDITLTKTIKPRRVSSINDNELTSSKA
LVGKALLNDKKVLVDISTGKGALGKDAIWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHTP
AEASTKWGTPESIADLTQVFINYLSGKVDVVPWADSSLSPETALIQEELFQLNEKGWFSV
ASQPAVNGCKSTDNIFGWGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNK
DGEIKSNLPIGPNVKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLWLEWARCY
KKNSKSFELLNSIYENYVLVSMIHHDFINENALWDLLLDE
>A0A7G2N485|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus sp|TrEMBL
MKITDIYKTKNKKDKAVISLEIFPPKTDAGVETIYKTVAGLTHKPDFISVTYGAMGSATQ
ENKTLKIAEKIKKDYGIETMHHLTSINNDPEEISKILSDIKAKNVNNILALRGDRPVGAE
ISKLPDDYHYAYELIEDIKKNGDFDVAAAIYPEGHVNSALEVENIEHVKRKYEAGANLFV
SQLFFDNEKFLRLNDYIRHSGIEAPIAAGIMPVLQKSQIERMIFFGASLPTRLIKIVNKY
KDSPDDLQKAGMEYACKQIDDLLARGVDGVHIYTMNKPFVANTMMEHYL
>A0A845MZ84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. BIOML-A1|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTSSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>A0A5F5Y7N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Felis catus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEASSGRFSVPPSISRNPAMVNEPRGDGGPTSRSEGSS
SGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCCQSQEQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDVCVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMWGEELTGEESVFEVFACYLS
GEPNQNGYKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNL
VDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A1G6Q988|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamwhitmania taraxaci|TrEMBL
MTITEHISNAQSTLFSFELLPPLKGENLQTIFNAIDPLLEFAPAYINVTYHREEVVYHKG
KSGAFLPKVLRRRPGTVGIAAAIQHRYNIDVVPHVICGGFSKEDTEDALIDFDFLGINNL
LAVRGDADKITGRFEPNPAGHPHAVDLIKQIVRMNNGHYNDENIESATPTKFCIGVAGYP
EKHTEAPNMANDLMYLKAKVDAGAEYIVTQLFFDNKKYFSFVESCRKVGITVPIIPGLKP
ISVKEHMSLLPRVFNVDLPEDLVRELVICNDNKSARELGIEWTIQQAKELKQAGVPSIHF
YTMGKSDNIARIARAVY
>A0A2D6YLL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR324 cluster bacterium|TrEMBL
MIIMRIIEMYQNQPFVFSIEVFPPKTEEGMENLQKKLRTFSSFKPDYISVTYGAGGGTRQ
NTQQLAGFIGNELGIEVLAHLTCVSHTRKDVSLLKEQFLDEGVENIMALRGDPPTAKKKF
EPMSGGYRYASELIEDLYRDRRFGIGAAGYPETHIEAISSQMDRYFLKQKIERGAEFVIS
QFFLENQKFLTWRDQLYREGVRIPIIPGLISAQSSSQIQKFAQMCGCVVPSKLIKKLERF
TGNAGDSLRVGLDHAEKQLEGLIREGVKGVHLYALNRVEVVNDLGPRMVSLKSKTDRIYS
EF
>A0A1Q9RTJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. CNS-004|TrEMBL
MHNGGRLPLLDGFSLEMTGRDAARLEEAATLLPAGTRVNITYLAGETPEQRVEAARAAGC
LGFTPVPHLAARRVRSSAELTEFLAALGEVAAVDEVFVVGGDPATPAGPYADGLAVLRSG
VLQEAGVHRVGVAGYPEGHPDIATTTLDEALRAKVALLTEQGLVPAVITQFGFDVQPVLR
WIHGLRRHGIDAQVRVGVPGPVGIKRLLSYARRFGVATSAGITRKYGFSLANLVGTTGPD
AFVAALAAGFDPVVHGDVRLHFYTFGGITATAAWVRDSRFAGRRRDGPREMQVRD
>A0A4R0PHJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oricola cellulosilytica|TrEMBL
MTSGSPPRPPQTDENPLGIDLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANAAD
VYERAAVFDGWVDAINAVDASGANAHMSSVGICALLTRMGYAPVFQISCRDRNRIAIQGD
VLGAAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRTMRDEGKFLSGRKLTS
APNVFLGAAINPFAPPYDFRPQRLAKKIAAGAQFVQSQYCFDVPMFHEYMKRVRDMGLHE
KCFIMCGVGPLASAKTARWIRSNVPGVHIPDDVVKRLEGATDQKAEGKRLCIDIINEVKE
IEGVSGVHVMAYRQEEFVAEIVHDSGALRGRKPWKREVRADDQLVADRLDDILHADNHRP
PQDIVGEKAH
>Q1PVP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kuenenia stuttgartiensis|TrEMBL
MSETMKSGSNLEKLLRDGKFAVTAELGPPRGADRTVIEKKAVMLKGYGDAFNITDCQTAV
VRMSSIAAGRIVLDSGVEPIVQMTCRDRNRIAIQSDLLGAAALGAKNVLCLTGDHQKFGD
HPMAKGVFDIDSIQLIQIVKALRDERLFQCGQELKAGGPAFFIGAAENPFADPFKYRAAR
LGKKIKAGADFIQTQIIYNVNKFKEWMKMVTDMGLHEKTYILAGVAPLKSKGMAKHMKYN
VPGMDVPDEVMERMDAAAEAKRGKEEGIKICLEVIEQVREIKGVAGIHIMAVEWEEAVPE
IVRQAGLYPRPSV
>A0A4Z1A4J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira jelokensis|TrEMBL
MNQILLEIVPRDINSVLQDVNFVKSNFHHITEINIPDLLRFDNRSWEVASSVRPIFSNVI
PHIRAIDFDINNCENLIHTLKSHQIPSVVVIKGDPPTDMSKRVYPTTSIQMIKKLKKEIP
QLRVFAAIDQYRVGIKNEFDYIELKKDAGADGFLTQPFFDMRLVDIFSEKLNGLEVYIGI
SPVITEKSQSYWESMNRAYFTKDFQPSMEWNVKFAKDVISYCSKNGMNAYLMPIRINLAE
YLHHIFT
>A0A4R7BW32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterovirga rhinocerotis|TrEMBL
MSAVSFRPSRHATRPIRVSFEFFPPKSEEMEKTLWSSIERLAPLRPNFVSVTYGAGGSTR
ERTHRTLERILGETALRPAAHLTCVAATREEVDEVVRGYRDTGVRHIVALRGDPLAGIGA
AYEAHPGGYAQTSDLVAGIKAISPDFEVSVSAYPEKHPEAPSLEADLDALQKKVDAGADR
AITQFFFDNDLYLRYLDKVHARGIDVPIVPGILPVQNFKQAKSFAERAGASVPEWLGARF
EGLENDPETRKLIAAAVAAEQVFDLVDRGVRDFHFYTMNRADLVYAICHLLGLRAEAGPA
AEKAAA
>A0A4T2AKB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinifilum sp. JC120|TrEMBL
MKIIDLINKNGQFISLEFFPPKDRESWPKFFEVVEKLKVLNPLFASVTYGAGGGTQDNSL
EIVKRMKQDAGIEPLAHLTSVGASPENISKFVSALQEANVENILALRGDAPVGDENFDFN
TQPFKHGSDLVTYVKDQHPGVGIAVAGYPEAHLESPSIKEDFKWMKYKIDEGGEFIITQL
FFDNRVYFDFCDRLKGMGIDVPVLPGVLPIMSLKSAKFILSLCGAAIPGKFLSALEKAHA
DGGDDAVYKLGIEFATRQAQELLDGGAPGVHLYTLNRAKACLEIGQALKF
>A0A3D4M1R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp|TrEMBL
SFEFFPPKNEKMGETLWRSVETLAPLGPRFASVTYGAGGSTRERTHQQVVRIQNEANIPA
AAHLTCVEATRDQV
>A0A1I6K4M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. cf046|TrEMBL
MSKTTHATANPQAALELVSGYSLEMTGKDVPGLMEAKDSIPAGTKINVTFLGNEDLEMRV
AAAKAVRDLGFLPVPHISARRLASRGQLEEFLSRLKDAGATESVFVVGGDPTTPEGPYED
SYDVIRTGLLLDYGVKEVSIAGYPEGHPDISNDVLWRALEEKSLSLSQQGLQATILTQFA
FDTDPVIAWIDQVRARGINSTIRIGTPGPAGIKRLLGFARRFGIGANAMIVKKYGFSLTN
LMGTAGPDTFVTDLSALLAADAKAGPATEGSAHGPVKLHFYTFGGLLATADWAREYTRAQ
S
>A0A4Q5TA09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium|TrEMBL
RAITQFFFEPETFFRFRDDATKAGITAEIVPGIMPVMSFAAVQKMSAMCGTDVPAWMARL
FEGLDEHPAARQLVAATLAAELCRKLYAGDVRQFHFYTLNRAELSYAICHLLGVRPKEAA
>A0A242CGU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus sp. 4G2_DIV0659|TrEMBL
MRTDTLFKEKTVFSYEIFPPKRTAPIDTIYHTLDRLKGQQPDFISVTLGAGGAGNNLSTA
DIAQKIQDEQFLPSVAHLPAVNFSKEEILAILKELKQKKVENILALRGDILPDKEPKKDF
AYANDLVAFIHEQGGFNIIGACYPETHGDAASSVEDIKNLKRKVDAGTNQLITQLFFDNQ
YFYTFKEKCDIANIDVPIQAGIMPVVNKKQIERMVKMSNVTLPLKFLKMMERYEHSPEAI
RDAGIAYAINQIVDLVAQGAAGIHLYTMNNPYVAQKIREATRSLFQA
>A0A349Y0G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp|TrEMBL
NPDFVSVTYGAGGSTKAPTLDAVRRMIGDSHLATAAHLTCVDASRDEVHQVVDEFRNAGV
RHFVALRGDPSTGIGTAYQPHPQGYENAAALVKGLKELGDFEISVSAYPEKHPESASEAV
DIDMLKRKADNGATRALTQFFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFA
GPCGTSIPAFLDERFEGYDEDLEGRARVAAEVAAEQIADLQRRGVSEFHLYTMNRAPLVD
AVLENLGLERLRRSAA
>A0A3D2PIR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp|TrEMBL
MRSETARRDGDIRLSFEFFPPKNAEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPTL
DAVRRMIGDSHLATAAHLTCVDASRDEVHQVVDEFRNAGVRHFVALRGDPSTGIGTAYQP
HPQGYENAAALVKGLKELGDFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQF
FFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPAFLDERFEGYDE
DLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A1V1UJR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp. A-2|TrEMBL
MKTPRISFEFFPPKTLEASFRLWDTVHTLSPLDPRFVSVTYGAGGTTRELTREAVSTLHK
ATGLNVAAHLTCVDASREETLEIADQFAAVGVTEIVALRGDPPKGSSGFTPHPHGFADSC
ELISALAETGKFTIRVGAYPEKHPEAADSRADIDWLKRKIDAGATEAITQFFFEADTFFR
FRDACAAAGINAPIIPGILPIENWTGARKFATSCGTQIPTWLDDCFDKAIRDDRHDLLAT
ALATELCSDLIEGGVEDLHFYTLNRPELTRDVCHALGVTPKVALRDVA
>A0A1S1CTQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC063B03|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETISDLDKVGVQKILALRGDIIPDVEPQKDFHYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A7L6UL02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. RHB35-C17|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGSGKPDMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGI
>A0A7U7EX04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus ST228|TrEMBL
MGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEFKYSDNAQYFGQVAQNLI
REGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKALFNPSQNKVRQSLTSKV
QERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSLATVRISNIAAASLIKQY
YNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKVGHLPGATNVYDVNSKG
LTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVKRLEKKIESGMSYFITQP
VYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPGIKMSDEILQQFEAVKDD
KAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAAYSKSITAHKEAIL
>A0A7Y6ZV01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPGNENMEKTLWKSVERLAPLKPAYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASTAELKQIARDYWDSGIRRIVALRGDLP
PGVSKTDMYASDLVALLKDVEDFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTSVYLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMYEGL
DADDQTTRNLLGANIAMEMVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVKPQNGGI
>A0A7T5R2Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micavibrio aeruginosavorus|TrEMBL
MNRKVSVSFEFFPPKSAEGEEMLWQRIDRLATLKPEFITITYGAGGSTRNWTVGTAGKAQ
MRTGIPTGAHMTCINATKDDVKEMAEALWQNNIRHIVALRGDIPKVDAPLDYNDFNYYHY
ANELIEGLRALHPFEISVGAYPEKHPEAPDLATDIRNLKRKCDTGVARAITQFFFENDAF
YRFLDLTEKAGITTPIVPGVIPVLDYDRMIRFAGNCQAHIPDSLKARLEPLKNQPEAFAA
AATELLCAQCEDLVRRGGIEHLHFYTLNHDDLPYSACQRLGLVP
>A0A6M5G211|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster bolteae|TrEMBL
MKIRDILAEGKPTLSFEVFPPKTEDAYDSVEKAAAEIAKLKPSFMSVTYGAGGGTSDYTV
GIASAIKEEYGVTPLAHLTCVSSTREKVHHVLGELKERGIENVLALRGDIPQDGSTPREY
HYASELIWEIKKAGDFCIGAACYPEGHVESANKSVDIDYLKQKVEAGCDFVTTQMFFDNS
ILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTYLPSRFMSIVDRFGDNPAAM
KQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>L7HEG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens BRIP34879|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGAGGSTRDRTINTVLQLE
NEIKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANEL
VSFIREESGDHFHIEVAAYPEMHPQARNFEHDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQTEHSLAIWNNLKLPR
>A0A5E4U313|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea capi|TrEMBL
MSGSLDNKTIMTQPSFSFEFFPPKTADGAEKLRATREQLFPLGPKFVSVTFGAGGSTQQG
TLDTVIEIQREGVEAAPHLSCVGSTKDNIREILNTYRGNGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGDWFHIEVAAYPEYHPQAKSPRLDLEHFANKVKAGANAAITQYFF
NADAYFRFVDDASRLGVTVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
ESIRAFGLDVVTALCERLLKDGAPGLHFYTLNAASATKAMWQRLGL
>A0A4R8D8H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2566|TrEMBL
MFELICEVEPPTRPDLKKVRHQIGVMSPIADGFLIPDNHIGRATVSSVAVANEVQLMGAQ
GIACLNSRDRNLLGFRRDLLTAAAYGVQRFLFVHGDDPAEGARTSQLTVRRMIEQTRETT
YPGCDPFKVGAATRLRPVPKWKAEADFLYVQVSYDLDELLRWRESVQLDIPVYAGVMVLA
SAQMARNLAGLPQLKIPAELIEAVERDRDAGVDHACEQILKIRDSGAFEGVHLIPVSRYR
QVAARLEREL
>A0P4P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilales bacterium HTCC2181|TrEMBL
MATLPPISFEFFPPRNEEGMQNLELVIKNLNLFDPDFYSVTFGAGGSTKEKTLETVLKIK
GLGSSAVPHISCISSSKKEISQVLKAYQSHNINQIVALRGDNPSGAVNYGDFKYANELVN
FIREETGDHFLIEVAAYPEFHPEALSAKDDMDNFKRKIDAGASGAITQFFFNVDAYFKFM
EECQKRSINIPIVPGIMPIYNIKQLSRFSANCGSEIPRWLKMKLEDYGDDLESLRSYGID
VITELCETLIQYGVPSVHFYTLNQSGIITKIINNLKS
>A0A5C8YKE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mendocina|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLAAYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEVAAYPEMHPQARNFESDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSDSIRAFG
EQVITEMCERLLQGGAPGLHFYSMNLAAPSLAIWNNLKLSR
>A0A1F3QTH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium RIFCSPLOWO2_12_FULL_31_6|TrEMBL
MKVTEHLAKAKKVLFSLEILPPLKGNGIQSIYDSIDPLIEFGPSFINVTYHREEFVYKKR
EKGYLEKIAIKKRPGTVGICAAIVNRYKIDAVPHIICGGFTKEETENALIDLNFLGIDNA
LLLRGDPIKTEASFIPEEEGHPYAVDLVKQVVGLNQGIYMDEDLQNANPTNFCIGVAGYP
EKHFEAPNLKNDLIYLKQKIDAGAEYIVTQLFYDNEKFKTFVELCRKEGIKVPIIPGIKP
LTARSQILTLPKNFHIDMPHELVEAVEKCKSDEAVKKVGIDWAIQQTKELIEFGVPCIHY
YTMGKSLSAREVVKAVF
>A0A1Y6BBP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogulbenkiania subflava DSM 22618|TrEMBL
MSTKPRTFSFEFFPPKTAESIAKLRTTRQQLAQFKPEFFSVTFGAGGTTREGTLGTVLEI
RNEGYAAAPHLSCIGSTRDNIRAILNEYRSHGIRHIVALRGDLPSGMGEAGEFRYANELV
AFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLNNFVRKVQAGANSAMTQYFFNADAYFRF
VDEVQARGVDIPIVPGIMPIANFGQLCRFSDMCGAEVPRWLRLRMQAYYDDTASIRALGL
DVVTELCDRLLTGGAPGLHFYTLNQAGIVSTIWQRLGL
>A0A2D9RXA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPGNEKMENTLWKSVERLAPLNPAYMSVTYGA
NSGERDRTHDVVKRIQQQTGVTAAPHLTCVDATADELRQIARDYWDSGIRRIVALRGDLP
KGVEKTDMYASDLVALLKEVHDFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTGVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKLYEGL
DADDQTTRNLLGANIAMEQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVKPQNAG
>A0A6P4K4L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila bipectinata|TrEMBL
MVSNDIHDHFYSGSNGGFNLSPDIFKEKLDAAGTLSTVLRLKRNTDLIPAAHLTCVGAPR
EAVDDLARCYRDAGVNHIVALRGDPSAGAVDDSPRPGGYTYASDLVTGLRRIADFDISVA
AYPETHPTALSPEADLDNLKRKLDAGATRAITQYFFDSEIYLRFLDRCLAAGITAPIIPG
IMPVSNYEQIVRFSAVCGVTVPAWLRYLFDGTAKNPELRRIVASMVAVEQIRTLQTYGIN
EFHVSTLNRSDLTYAIAHILGVRPTQTNASRNVTDLLETTEVPDDRETPADFDPTKGTQE
GAPPFMLRTLFG
>A0A0D7W1F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tamlana nanhaiensis|TrEMBL
MKVTEHIKNANGKTLFSFEIVTPVKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVE
KNGLLDRKTVRKRPGTLGISVSLKHKYNIDPVPHILCGGFTKEETEYMLVDCHYLEIDNV
VALRGDAMKHQKYFEPTKGGHTYACELVQQITDLNSGKFLHEENLTEFKTDFCIGVAGYP
EKHMEAPSLQTDLKRLKAKVEAGADYVVTQMFFDNQKYFDFVKMAKDAGIDIPIIPGIKP
LAVNRHLQLLPHVFSIDLPEDLINAVDACKDNKAVRQVGIEWAIQQSKELKEAGVPVLHY
YSMGKSDNVQAIAEALF
>A4VRF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri (strain A1501)|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKAQLRELLNLYKSAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVQTPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A2X5C0Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia rubidaea|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHGIIKGIKDRTGLDAAPHLTCIDASREQLSAIASDYWNNGIRHIVALRGD
LPPGSGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPIAAA
>Q3YV32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella sonnei (strain Ss046)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>F8P6Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serpula lacrymans var. lacrymans (strain S7.9)|TrEMBL
MKLSEKIAAYNSPHPFYTFEFFPPRTDQGFENLITRISRLSSLNPIAISITWGAGGSTKE
RSLDLAGLTQAEYEIDTVLHLTCTNMKHGMVDDVLKAAKARGIQNILALRGDPPRGQEHW
IPIDPRFNHGIDLVTYIRSHQYFSSDFCIGVAAYPEGHPDGETDEDKELEFLKAKVDAGA
DFIVTQLFYDVDRFLHWVKRVREIGITVPIIPGIMPIQTYSSFLRLIKLCGVSVPSSIMS
DLESIQHDDQMVKDYGVQLAIDTIKRITTKGTVPGIHFCTLNLEKSVQLVLENLQWAGGS
PVTKNKLIAETPGSIIHPLPGSELIITPSSATSSAANALTTKQTADTEVGRGEVNYAATW
DDFPNGRFGDYKSPAFGDLGPWGAPVLSRTEVIDEWGSPKTEQDLTELFVRYLHSEITTT
PFSPSALSPESLRILSHLERLTQRGWWTVGSQPAVDCGNSTDPVFGWGPRGGYVFQKSFV
EFFADEEAVKEIVQKIEKEGQGVVHYFAGNMQGECRSNVPEDGRNAVTWGIFPGQEIVQT
TIIERESFLSWKDEAFSIWAEWASFYPPGSQERELLDVVMQKRWLVSIVHHDYRNPGGLW
TFLFGGNIAL
>F5XSN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microlunatus phosphovorus (strain ATCC 700054 / DSM 10555 / JCM 9379 / NBRC 101784 / NCIMB 13414 / VKM Ac-1990 / NM-1)|TrEMBL
MTEPSSASGTTPSARPSLPTLVEQGRGGMLLFGITPPKTSTTVEDRARIAGITLQRLAHL
DLDGLLLYDIDDESDRVTDDRPFPYLSTIDPAAYYVDHLGAWHKPVVLYRSVGKYGPDQL
GAWLDQTDPSQQLGVFVGACSRDHVVRTTLRQAQQLRADRQPDLALGAVMITERHTARGD
EHLRMLAKQEAGCSFFVSQVIYDIDGTRSVLSDYFYACAERGIAPRPVIFTLAMCGSLKT
LDFLQWLGIQVPRWLQNDLRYTDDPLHVSYAHCLHAAEDLAAFCRRLGIPYGFNVESVAI
RKAEIEAAVELAGNLRPLLR
>A0A7Z9BFB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktothrix serta PCC 8927|TrEMBL
MNRFRTACQTLNEFIITAEVAPPKGADPSHMIEMVRLLKGRIHAVNITDGSRAVLGMSSL
AASIILLHHGVEPICQIACRDRNRIGLQADLLGAHALGIRNILALTGDPVKAGDHPDAKA
VFDLESVRLLQAIDKLNQGLDWNNKALPDGATDLFPGAAVDPQSSSWSGLKSRFERKLQA
GAQFFQSQLITDFDRLDKFMTEIADGTQKPILAGIFLLKSAKNARFINKYVPGVCIPDTI
INRLEKAKNPLEEGILIASEQVKTARQLCQGVHIMAVKREDLIPKILDLAGIKPF
>A0A6A8VPM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELVPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A0C2UW75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. VKM B-2647|TrEMBL
MTKPDLRSALAQGRLVGDGAMGTYLYQMGFPVGISYEELNLLQPDVIRGVHRRYVEAGAR
LIETNTFSANREKLSKYGLEGEVEAINRAGVKLAREAAGDEAYVVGAIGSIRAGKRKNVR
TSRVVEALQEQIAVLLESGVDGVLLETFYDLEELMLALKLVRRAGGLPVICQFATDGTGA
TQDGVPLHEAFARLQEAGADVVGFNCRSGPNGILRAMEKLAVPDGLFTSVFPNAGMPDYV
DGKYSFTAGPDYFGASARRFADLGVRLIGGCCGTTPEHIAAVAAALRGYEPGGAGQQLAP
QPAEAAAVTVRPLAAAPAAGTARPQEPSLLDLVKQRHTVIVELDPPRDLSIDKFMAGAAA
LKEAKADALTLADNSMAVTRMSNLALGYLVREQVGLRPLIHIACRDRNLIGTQSHMMGLH
ALGIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQRAQFVV
GAAFNPNVKHLDKAIQRLERKIEAGADYIMTQPVYDPALIERIAESTSHLDVPVFIGIMP
LASGRNAEYLHNEVPGIQLSDEVRARMAGLEGTEGRRVGVDIAKELLDTAMRHFRGIYLI
TPFLAYEMSVELALYVREKASRDFHLSPLAK
>A4S8H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ostreococcus lucimarinus (strain CCE9901)|TrEMBL
MTLVDALKDTSRPVFLFGVTPPLEGSSADAIADAADNFVQKSRGLACDGYIVYDIQEEAG
RTADARPFPFRKLDDPGAFAAALRKASGGTESVVYKCVAETKSEGEFQSWLDEATRETSA
YNLVGGASSSQEYAGPTIQRAAEMLRKTKRGCAFGGVTIAERHAKKGNEHETLCAKTDAG
AEWFISQAIYDADMTIKLVNDYGAECERRGIQPKRIVLTFAPCGREKTMKFIKWLGCSVP
EAVEAEILGADNPAQKSVEILVAMCERIIAETKQSKVPLGVSVESVSIFKNEKEAARDLF
RLTQAVMLDAYGVQWSMRYAIDASSSKRAGKDDKIKRIATVVAAFLAGAVARTKFA
>A0A7Y0FJ68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium cheonjiense|TrEMBL
MKITDHIKNANGKALFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRTTRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTTGGHGSAMELVHQINNLGRGKYLHNEDQECDEHNKFCVGVAG
YPEKHIEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVKKAREMDIHVPIIPGI
KPIATKKHLKLLPQVFKIDLPEDLINEVENARNNEAVKQIGIEWAVNQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A455B2W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Physeter catodon|TrEMBL
MVNEPRGHGGPSPRWEDGTSGSESSKDSSRCSTPVPDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKRLGLKNILALRGGDGWEEEEGGFSYAVDLVKHIRS
EFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVKACS
EIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQALS
LCQELLASGSVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRP
IFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEE
LTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINS
QPNINGKPSSDPIVGWGPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVK
GDNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESP
SRMIIQYIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLNRPPQGKRETEAP
>A0A455B2W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Physeter macrocephalus|TrEMBL
MVNEPRGHGGPSPRWEDGTSGSESSKDSSRCSTPVPDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKRLGLKNILALRGGDGWEEEEGGFSYAVDLVKHIRS
EFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVKACS
EIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQALS
LCQELLASGSVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRP
IFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEE
LTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINS
QPNINGKPSSDPIVGWGPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVK
GDNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESP
SRMIIQYIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLNRPPQGKRETEAP
>A0A8H4VXJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cudoniella acicularis|TrEMBL
MHISDMLAEAERSKQPKFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
SLTCEMVNVAQTQYGLETCMHLTCTDMGKEKVDDALRNAYKAGCTNILALRGDPPREQEK
WEATEGGFQYAKDLVKYIRQTYGNHFDIGVAGYPEGCDDQDDPELLLDHLKEKVDAGATF
IVTQMFYDVDNFLTWVSKVKAKGVTIPIIPGIMPINTYASFLRRCNHMGCGIPPKWSEAL
EQVKNDDAAVRSIGTGLVAEMCRKILNSGLIHHLHFYTMNLAQATRMVLDELELTPSDER
QLKKPLPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEQNRKLWGEPTSIKEIADIFVKYLENGVESLPWSEAPITSEADAIKPDLI
SLNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVSPKLMDELVRRIERD
PDLTYYAVNKAGNLKSNSPGEGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMD
WAHCYSALSPSRQLIENTMETWYLVNIVHNDFHQTHGLFPLFAGLSVEDIDKPFEVEHTN
GVNGTKLGGVENIPLVNGEAPKA
>A0A0V8RSU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schaalia odontolytica|TrEMBL
MPFSDDAYACPCTHDHEPTLLSFEVMPPRKPSLEEPFWNTVDQLLRVRPDFMSVTYGAGG
KDRSNARATVRRLVRDTPIQPIAHLTCVGNSTEEVVSTVYDYLDSGVRTFLALRGDPPVG
QEGWEPGPGGVGSATELIHLIRTVEKRRCDAHPGEALRSAFKPLTIAVAAFPAGNPAAGT
TPAQEVERLLVKQAAGASFAITQLFWDAEVYASFVERARRAGVTIPIVPGLLPATDPARL
RRVQDLTGIEVPEYLLTTLADYPHQEARDEFGAVFGSRLFHSVLEAGAPGVHLYTFNRSK
PVLDILTLLGVKPDPLRSQASAPDTRA
>A0A5B8W362|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter ginsenosidivorax|TrEMBL
MKITEHIKNAAGKTLFSFELIPPLKGQSIKGIYDAIDPLMEFKPPFIDVTSLREDFIYKQ
HDNGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLVDLQFLGIEN
VLVLRGDARRGDASFVPTPNGHNYATDLLQQVVNMNNGIYLHEHNDDSLKTDFCIGIAGY
PEKHFEAPNLKTDFKYLKQKVDMGANFIVTQMFFDNQKYFDFVNNCRANGINVPIIPGLK
PVTNSKQLIGLAKTFHIDMPEDLCDAVNGCKSEKDVRDIGVEWMINQCRELMAFGVPVLH
FYTMSNAGPTKRIAEAIF
>A0A1C4W278|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora viridifaciens|TrEMBL
MALGLPSVLPNSQPAIGELIRDGQPTFSFEFFPPKTPQGERLLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGNPGGEWVRHPEGVRYAEELVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTKYFVR
KCRAGAAFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQMGTIERSVQLSGAPF
PPALAERFARVADDPEAVRRLGIEQASEMCARLLDEGVPGIHFITLNRSTATREVWQHLR
ADARV
>A0A1A8MIZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius pienaari|TrEMBL
MNVAAPFTVMVNQVQRVDGSWLSCKSDSSGTSNSGGESSKESSRCSTPVLDAVRSDRLRD
KMRRRMESGDQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKET
SSMMIASTAVNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEE
EEGGFNYAVDLVKHIRSEFDDYFDVCVAGYPTGHPEAESYADDLRHLKEKVDAGADFIIT
QLFFRADTFLTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPI
KDNDAAIRNYGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPL
PWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFY
LKSKSSKEALLQMWGEELKREESVFEVFTCYITGQLNRNGHKVMCLPWNDEPLAPETNLL
KDELEKVNRRGVLTINSQPNINGKPSTDAVVGWGPAGGYVFQKAYLEFFTSSENVNALLK
VLKKYEPRVNYHIVNVHGRNLTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEA
FALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWRVLDDMFELLDAPL
ETLADGMSGDGSHGNGTLAE
>A0A0Z8DPE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPATYLTKEKVRSVLHSLDEIDVHQILALRGDIIEGLLPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A224AB85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blattabacterium cuenoti STAT|TrEMBL
MKVTEHIVKAKKSLFSFEILPPLRGCDIQDIFSTLDPLMEFHPPFIDVTYHREEFIYVEK
ENGLLQRKKISRRPGTVGICAAIMNKYRIDAVPHLICGGFNKQMTENALIDLNFLGINNV
LVLRGDPLKSEKNFIAPKDGHKYAVELVKQVKNLNVGKYLDTTFLEKKESPLFDFCIGVA
GYPEKHLEAPNMESDLFFLKKKVEAGADYIVTQMFFDNKKFFSFVKKCRSKGISIPIIPG
IKPISSRNQLNGLPSRFYLNIPNELVKEVEKAKNKKNVIHVGIEWAIHQSKELKNSGVKV
IHYYTMDRPENIYKIVQAIY
>A0A1F1YNL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC30G07|TrEMBL
MRGTIASTRLSASAPLDTAEEALGTGLETGPGADQGVSRRSRTALSFELIPPRNTADTEK
LDELIGGLAAYHPDYVSVTSSMRSDWLEGTSALIARIASTTDLRPIAHLACTAGTKVELE
GWIRQLIDAGVRGFLALRGDLQPGQKALPEGYLPYATDLLNLINEVQEEEAFRLAAGKLA
LSVACYPSGHAESKNFDHDLDVLLAKQRLGADFAITQLFFDAADYLEFVEVARMAGVRIP
LIPGIMPITSLARAKRMGELSGLEVPRGVEKQLSSAATGEEEYELGMELSADLARTILNA
GTGGLHIYTHNNLAVTRDLLQRIGIEHKD
>A0A4P6XY06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metschnikowia aff. pulcherrima|TrEMBL
MKIAEKLKQAHSCANPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSLLTNEMVYTAQLTLGLETCMHLTCTNMPVSYIDEALDKAYKAGCQNILALRGDPPLD
GSESTGDFRYAKDLIAYIRKNYGDHFNIGIAAYPEGHPEEENSANLMQYLKEKTDAGADF
IITQMFYDVENFISWCREIRAAGIHIPIIPGIMPILTYSAFVRRAKWSQVKVPQHFFDAL
DPVKDDDFVVREIGTQLVAEMCQKLIDSRFVNHLHFYTMNLERSTIMLLETLNLIECVKE
NEAVGDVLPWRKSLHPNRSKEAIRPIFWQNRKYSYISRTSGWDEFPNGRWGDSRSPAFGD
IDLSASELLRQSPKRALELWGCPQEVKDLANIVVKYLKNDVKALPWSDGPIGSDTDILKE
SLIKLNENGFITLNSQPALSAVRSNDKIHGWGPKNGFVYQKQYLEFLVHKDLALKLVDAV
EDHNQRDPTGLITFYLVDKEGRLTTNSKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWK
DEVYSLLDEWVTIFHLKAIGELVAPEKVEAFSKFLTGFGNDYVLCNLVNNDFTSDNNVMF
DLLHGLGASH
>A0A6S6RSD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Portiera aleyrodidarum|TrEMBL
MKIKKNMNKNELEISFEFFPPNETYKIKELLSLIKTLYKKINITFCSITFGAGGSNKRKT
LEVIKNIKNNNIECVPHLSCISNTKKEIIKIINIYKKLGIKTILALRGDMNKNDKLKKNN
FINSLDLITLINKKFYKKFEIIVSAYPEMHPNTINFEKEVCFIIKKFLFGANKAITQYFY
DPDSYFYFLEKVSKYGIDKPIIPGIMPIINVKNLIKFSNKCGANIPKWIYKKLESCKTKN
DIENIGKEIVIKLCEILIKGGAPGLHFYTLNKIEPTLNILNELIT
>C8W5Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofarcimen acetoxidans (strain ATCC 49208 / DSM 771 / KCTC 5769 / VKM B-1644 / 5575)|TrEMBL
MKLSEIFKTGKPTLSFEFFPARNEKAAETFNQTIEDLVELKPDFVSVTFGAGGSTKEGSY
ELVKKLKKEKELEVVAYLAAFALKKDEINAVLNSYQDLGIENILALRGDPPKDADVTQVS
AESFKYASELAAFIHQNYSFCLGVAGYPEGHIEAPSLKKDIEYLKHKVDQGVDFIIAQFF
YDNVCFFDFRERCQKSGINIPVLPGIMPVYSVKMMEMLAGSCGAKIPEKLRKGISELPEG
DTKALVDFGIEYATGQCEELLKEGARGLHFYTMDKSESTVGIVKGLRNRGFLTI
>A0A150MW47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. B4113_201601|TrEMBL
MGLLDELKQRVLIADGAMGTLLYSHGVDRCFEELNLSKPEDIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSAVPLDEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPVIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYYMLQSLEEVPLPTRAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLLGGCCGTTPNHIEAMARALQDRTPVTEKTVKRRAVPVS
VQSDIPSSATPLPELVRARRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLA
TPRISNAAVAAIIKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVER
MEKKIQCGAHYFLTQPVYSEEKIMAVHEATKHLNAPIYIGIMPLVSARNAEFLHHEVPGI
TLSDDIRARMAACGDDPVRAAREGIAIAKALIDAAFDLFHGIYFITPFLRYDMTVELVRY
IHEKEAAAKERKVVHG
>A0A2N2KHV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-12|TrEMBL
MQENHFKNSLLKSGVFVVTWELVPGRGARETAQDMALAQAKQAVDGRKIHALTVTDNPGG
TPAMSVSFMGGEIQKLGIESLVHFTCKDRNRNQIESELYALDRSGVRNILVMSGDYPVSG
FQGRPAPVFDLDPLHTLQLIADMNRGLAYTGAKGTVCHQPADFFPGAVVSPFKATEAEQM
VQYFKLKKKIAAGARFIVTQLGYDARKFHEVLLFLKQNGLNIPLIGNIYILPYGAAKMMN
RNDLPGSVVTDKLLADLDRERNDPDKGSGARILRAARLYAVLKGMGFAGVHIGGHNVKYE
QVEEIIRRGEALTPQWSELIAHFDYPLPGGFYYYERDPATGLNLESPTRRQDRPPDAAIE
SIYGFSRFFHKLMFEPGKKFYGVMKGLCRTVAGTKMEVPFSKLEHWTKVVLFDCKDCGDC
ALIDLAYLCPMSQCPKNQRNGACGGSFAGWCEVYPAKKKCVYVRAYARLKKHREEMQLEK
SLVPPCNWDLYQSSSWINFYLGKDHTSQRQQRSAPEDSR
>A0A7U0S9H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDAEQGERLLDKVKEGLTILVELDPPRTFDTTKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKAKIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDDVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A8H9MSR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDAEQGERLLDKVKEGLTILVELDPPRTFDTTKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKYEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKAKIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVRIGSK
>A0A7U7QNJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEIFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDAEQGERLLDKVKEGLTILVELDPPRTFDTTKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKAKIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A7W9SY91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter luteus|TrEMBL
MKVTEHLTRANGKTLFSFEVLPPKKGENIQNLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGFLEKKTVRKRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFKPDPDGHAYAADLIGQVANLNKGEYLDEEQDDTWATDFCIGTAGY
PEKHFESPNYGADLRYLKHKVDRGADYIVTQMFFDNEQFFNFEKRCREAGITVPIIPGLK
PLTTKSQLTMLPRAFYLNIPEELADAVHLAPDNAAAREIGIEWCINQSKELMAHGVPVLH
YYSMGKSESIRRVAAALF
>A0A0M4D9H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas soudanensis|TrEMBL
MKTLNPRSALFLERLAEEVIIGDGAMGTLLYSRGIPLDVNFEYLNLTSPQQVLQVHRDYA
AAGARLLETNTFGANGAVLGAIGLEKKVGAINEAGARLAREAAGELCFVAGSVGPLRRPR
GEAQEIPPSQKEALLAEQMEALAQGGVDLFILETFASLADLELALGVAARLGLPAVAQMA
FIEDGRTREGLSAEEAARRLTQAGATVLGANCGSGPRELLRVLERMAGATDRPLSAFPNS
GFPQYLDGRYIYLATPDYFAAMASDMAGAGASLIGGCCGTTPEHIRALAGALAGVKPAAR
ARVRRVETPVRPEAGIPSTASRTFLDGWGRRPVVTVELDPPRGFDCGKVIEAARALTAAG
VDAISLAENPLARIRMGNMALARKIEEDTGTPVIVHVTCRDRNLIGLHSELMGAHLLGLR
TLLAVTGDPVSVGGEAGATSVFDLNSIGLLELLSALNEGKSLLGADLGGCSQFLLGAAFN
PNLPSMDGQLRRLQKKIAAGARFVQTQPVYSPQILDELLARTAPLQVPVLVGLLPLVSER
NAEFLHNEVPGISLPDGVRARMKGKSGGAGAAEGMAIAGELVEGCRGRAGGFYLMPPFGR
VELALELMALIRRKA
>A0A096P865|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ostreococcus tauri|TrEMBL
MTLVDALMDPSRPVFLFGTTPPLDGSSADAEREAAENFANKARGLAADGYIVYDIQEEKG
RTEDARPFPFRKLADPGSFAKALKRATNGGESVVYKCVAETKSEEAFKEWLADATRATTA
YNLVGGASSSQEYAGPTIARAAEMLKEANKKCAFGGVTIAERHAKKGNEHETLCAKAAAG
AEWFISQAIYDADMTIKLVNDYGAECKKRNIKPKKIVLTFAPCGREKTMKFIKWLGCSVP
EAVEQEILTAQNPAQKSVEVLVAMCARIIEETKDSGVPLGVSVESVSIFKNEKEAAHDLF
RLTQAVMLDAYGLDWSMRYTIGGKPTTKTEKPSITERQLGDENVAKRVAVATAAFLAGVA
VRGVTSRR
>A0A7U7P0N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDKAYLAVYPNASLPEVQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLESTKPILEKEVRPIL
ELVPEEVEDEDSGERLLDKVKERLTILVELDPPRTFDTSKFFEGAKELNEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVQLIERKVEYGADYIITQPIYDVNKAVLLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEQGRANEEGMTIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYVQNKQQLQIASK
>N8Q8Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bohemicus ANC 3994|TrEMBL
MTLADRVHSDHDIAPLEASQHYPDSVDKVLHFSGKGRDIQDFDVFLQQAKSANIQNLLLL
TGDKLKEHHHGRDGAPRTRYLESVNAVMAAKQHGGFQIGVAFNPFKYAEAERDAQYLKLH
KKIKAGADFIITQLGYDIEALKQAKSFLTHHHYPQKILACVMPLSLERARFMVKHKVAGI
VITPHMLKVLENEKLAGFTDRVYLRCALQILICKYLGFAGIHLSACHKPEEQILLESYVE
EYRHLELDALELLWNSLWQVKTSKAFMPELPYFSRQPTSSQIIKYQHLHLMHDALFESKI
AKGIGKFIFKANFWDKSAAANALLKTEFVSKHGVLGCESCGQCRLGDTLYICPETCPKGL
ANGPCGGTTLDRCEFGDRECIHSVKARLAKAVEQTQVLKEKLIPTVPIEVRGTSSWNQFV
EKLVFGDRSLSFIIHGI
>A0A4V1DZZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia sp. 2-6|TrEMBL
MKVTEHIAQSKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGEKYFEPTKGGNRYASDLVTQINDLGKGKFLHGEISGNDLNNSFCIGVAG
YPEKHLEAPSMQYDLKMLKQKVELGADYVVTQMFLDNQKYFEFVKLAREAGIDVPIIPGI
KPLAVKKHLQLLPQVFKIDIPEDLVNAVSQCKNNEAVKQVGIEWCVQQCKELLDFGVPAL
HFYTMGKSDNIQKIVSEFF
>A0A2S6MVR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoblastus sphagnicola|TrEMBL
MDTQRPSRERHKPLDVSFEFFPPKTDEMDANLWEAIGRLAPLKPKFVSVTYGAGGSTRER
THATVARIVRETAIAPAAHLTCVGATREEVDEVARAYWTAGVRHIVALRGDPQGGVGGAY
APTPGGYAHSTDLVAGLRRLHDFEITVSAYPERHPESASFDQDLDVLKRKIDAGATRAIT
QFFFDNDIYFRFLDKARKAGIDIPIVPGVTCVQNFKQTASFAKRAGASVPDWLGERFEGL
DDDLATRRLIAAAVAAEQVFDLLDRGVERFHFYTMNRADLVFAVCHLLGVRAG
>A0A1F6TBU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Muproteobacteria bacterium RBG_16_65_31|TrEMBL
MQTQKKFPRAFSFEFFPPKDDDGRAGLRDAINQLAPLKPKFFSVTFGAGGGIRAGTYETV
KEIQARGLTAAPHITCTGTTRADVKQLLRSYRELGIGRIVALRGDRPKDAPAAGDFSHAN
ELVAFIRAETGRHFHIEVAAYPEIHPEAPSAATDLENFARKVRAGADSAITQYFYNPDAY
RRFVDDCEALGLDIPIVPGIMPITNYKQLARFSDGCGAEIPRWVRKRLEGYGDDLDALRA
FGLDVTTALCEKLLAAGAPGLHFYTLNRAGAARALWERLGL
>A0A2U8U0J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 31-12|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VQFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCDRLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A5M8PWM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lasallia pustulata|TrEMBL
MEKITDKIAALPKDGTYFSLEFFPPKTQMGFSNLQARLERMSRALRPLFVTVTWGAGGST
SSKSLELAEICQRQLGLTTCLHLTCTNMRRKLIDEALEEAKALGIRNILALRGDPPRSEE
YRLNDGALEDGGEGEEGDSNEEFTWAIDLVRYIRRVYGDYFCIGVAAYPEGHADESYPEV
QDPLHDLPYLVHKVQAGADFIMTQLFFDVNAYTSFEKLLREHESGAFKDIPIIPGLMPIQ
SYQILKRTTKLSHAKLPPDILDRLEGIKGDDEAVKRVGVDIISEIVEDIKAVKAAGPRGF
HFYTLNLEKALAFILERTKLIRPSTPGSNDDSAIDDSFPFSKGTRAHTNGVNNVDGTGKS
HPRKDFDRRRLSSTTSPHNRIIVDPPPSSHNSTISASEAGHPTSPTLASRATTLAISSGE
GSLGREATWDDFPNGRFGDARSPAYGEIDGYGTSLHVSISYARQLWGAPSTRQEIGKLFV
RHVQGDLESLPWSEGDVNAETAVIRKELVALIDQRGWWTVASQPSVDGVLSSDPIFGWGP
AGGFIFQKSFVELFLPAREWKSRLRPHLESAAVSAEVSWYAGNAAGEFESSEAAEAVNAV
TWGAFPGKEIVTPTIVEEVSFRAWMEEAFAIWAEWERVYYGRGLGDEETRRLLRECREGC
WLVNVICHGYREAGRLWEILMEA
>A0A5P9HVS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp. THAF9|TrEMBL
MSTPTVSFEFFPPKSLEASFRLWDTVQSLAPLDPTFVSVTYGAGGTTRELTRDAVATLHK
SSGLNVAAHLTCVEATREETLAIAQDFAEAGVNEIVALRGDPPKGSNGFTPHPDGFADSC
ELISALADMNRFKIRVGAYPEVHPEAADAQANIDYLKRKIDAGASEAITQFFFDTEAFFR
FRDACAAAGIDAPITPGILPIENWAGTKRFAAACGTKIPAWLDEAFTKAARDDRETLLAT
ALATELCSELIDGGAEHLHFYTLNRPELTRDVCHALGITPKVELRDVA
>A0A396PDN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. TM10-2|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLVDGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A2N7J169|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 10N.261.49.E11|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>F0EYW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingella denitrificans ATCC 33394|TrEMBL
MTTKPFSFEFFPTRTPEGRAKQVITRKQLSQFNPSFFSCTSGAGGSTREGTMQTIGDILS
EGIAAAPHLPCIGMTADEVKALLTQYKAMGVKHIVALRGDIPSGIGLGMDGMRYANELVE
LIKTEHGSDFHVEVAAYPEFHPQARSAEDDINHFVRKVNAGADSAITQYFYNADAYFRFV
DDVQGRGVRIPIIPGIMPIASFAKLARFSDTCGAEIPRWLRLKLQSYADDSASIKALALD
VVTDMCERLLREGAPGLHFYTLNQAGLVSTICQRLGY
>A0A3D1K6I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaeria bacterium|TrEMBL
MLAMTDSFVLKLLRKAFIMADTGKPLIQHLNSGFIVSCLTLEDCIRDAGGDLSRGADILN
LTRPDLITRLHGEFADAGAMLIATNTAAANTFCLRRIGIADKMREINIAGAKLAISGAGK
TAFIAGAIGPLGLTLDEDWDMETLRDAYVGQITALLEGGVHAIQFLSFVKLEELAFAVGE
ARQLAGKDFPILAQMIFSDNGLCETGENVEIAAARLVEAGADVVGVNGGQSISASVKAAE
RLAASAAGKLVAAHPNAGYPETAEGGRLIYMASPSYMGDTAIRLAKTGVRIVGGFSGTTP
EMVRAMVLALTTIRAAPVVSAPVKAQAPATAIPAKFKQGAFLESLTMTHPVIAEIDPPPN
LLSAGIVEDARVLVAAGAQAISMAENPLASLKMSNMAMAAIIRRELEVHTICHLTCRDHN
LLGTQSILMGMHALDIRAVLALTGDPLTASAGQGRSVFDLNSFLLTRLIAKMNTGLTNSG
ASLKGETDFSIGVAFNTGARNLENEVQRLHRKVDEGARFVMTQPVFDPGHARRVMDLIRM
PGLRVFLGFFPLVSARSALYLHNEVPGIRIPEPILAQLTSLPNKEDQEKAGLESSSNLLE
SLRTDLDGVYLISPHNRPRLLAPLIRQFRPG
>A0A3D3JW11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaeria bacterium|TrEMBL
MAEEPQKPARPSGAWNKSSFRALLQDTDTFVHCVELVTSRGLITERRGRRMLQVARQLVE
HPDIHALSITDNPGGNPMINADTMGTDLIARGQEVIIHLSCKDWNRNALQGRGWQLASDG
FRNILAMSGDYPVGGYHGQASGVFDIDSVGLLQMLSEMNDGGSVDGGKPAAQSTGFFLGA
VVTNHKKLESEVMPQYFKLAKKIRGGAEYIISQIGYDARKQDELIKYMRMHNLNVPVIGN
VYVLGGRAARYFYSGKVPGVVVTDKLMQLVEKHTADEDKGKSFFLEFAAKQCAILKGLGY
RGVYIGGHLTYDDYALVLERAASYSDTDWKSFADNICYQQSDEFFYFEQNPMTRLNTTTV
NRLYKRSKDAAMIDQSRRRAPITYRLNRVVHDKVFERNTTGFKAARKISELIDKAPAVVQ
RIIHGAEHVAKIAAFDCRDCGDCSLPEIAYLCPESQCVKNQRNGPCGGTRQGKCEVGEKE
CIWALAYNRLKAYGEEETMLDGPVVIKNGALEGTSAWANRFLERDHQADSADTTPEPGVD
KKSNSSGKTA
>A0A7X9EVY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MKIKELYKSGQPVLSLEIFPPQVDYPLESIFVTLDHLVELNPCFLSVTYGSGRGDRPRTA
EIASRIRQQYGLEALAHLTGVGHSRAEVDEILDQLIAAGIENIMALRGGLPLGDPGFDRA
EQGYRYAVDLIRDAKRKYDFCIAAAAYPEGHPESRRLSQDVIHLRQKVNAGVDVLITQLF
FDNRVFYDFMEKAQRVAINVPVVPGIMPVLNANQIKRIIYLCGVSMPASLLKLVDRYQHD
PEAMAKAGVEYASNQVQDLLKNQVPGVHLYTMNKWAQVSEIIHNVKLR
>A0A1M3NFA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium 68-20|TrEMBL
MARLLEALEGGPLVVDGAMGSQLFERGILHNACLEELCVSKPEVIRKVHEDYVRAGAQVL
ETNTFGANAMRLEKYGLATKVKELNEAAVKVARDAAGAKAFVVGALGPSGYFLGEALPDD
LSKVRAALHEQASVLVDSGVDGILVETFRQTNELRIAIESAVAAAGGKIPVIASASVDER
SRMADGTSSAEIARLMREWGASVVGVNCCDGPMNVLEAITPMLELGIPVWAVPNAGLPRR
VDERLVYVSTSEYFGVYARRMFKLGVKLVGGCCGTTPDHVRRIAAAARMAGAAERGATAQ
GESDAVIRAGESFEAWSADPPESPSSAKCVPFADRSDLAAKIARGQFVVSVEVNPPVGLD
LAKAIGAAKMLKAGGVDVINIADGARAQARMGNVAMAMRVQEQCGMETILHVCGRDRNLL
GTLAHLLAAHELGVKNLVIVTGDPPKMGDFPDASAVYDLDSIGILKLAARLNYGIDPGGK
ALGGATRFVLATGAEPAALNYERELARLKQKKLAGAQIVMTQPVYDPAVLEKFLEDIAPL
GLPVLVGLLPLASYRNAEFLHNEVPGMQVPEAVRERMRKAGSGAQARKEGVAIAREMLAA
VRSRVAGAYIMPPLERYELALEVVDGFLESEPALTTAKA
>A0A3D1UMJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaeria bacterium|TrEMBL
MMNDRLKKLLSEKTVIFDGAIGTEIYKKNFFVNTSYESLCLNNPKVIREIHLSYKDAGAE
VLTTNSFGANFNTLNKFLLGDKVGEINRAAVRIAKEVAGEELLVAASVGPAGDIPNGSAW
DVNRIAAILMEQIAALAAEEPDFILFESLGGARDLQAALLAMELCPDMPSVTSFALNRDA
ESRTGDSPARLLTIIDEAKFKPVAVGLNCGIGPEGMLNALEILMPLCHLPVIAQPNAGCP
KSVDNRMIYMCSPEYFTTYAMRFAALGVHGVGGCCGTGPEHIRDMARSINPLNKAAHNTG
RLVVTEAALPEKTPVPMKEKSRFAAKLATGQWVTNVEIVPPQGYLLEKTIEKAKQCRDAG
FDAINIPDGPRASSRVSPLVTAFKIQSEAGIEAILHFCCRDKNLIGMQADLLGCAAMGIH
NILFITGDPPKLGDYPFASGVFDMDSIGMARIQSRLNRGIDLGGKAIDTVTQALIGVGAD
PNAIDMKREIRRTREKIEAGAEFLITQPVFDTAPLLRFIDAVPGLSDLPVIAGIWPLASY
RNAEFMRNEVPGVTVPDSIMERMAKGKTKEEQRAEGIRIAREAVASIRDKVAGVQVSAPF
GNVQTAIAVIQKT
>A0A4P6K1U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ktedonosporobacter rubrisoli|TrEMBL
MEHQLLDQLRQGPVLGDGAMGTLLYARGVAYKECFDALNLSQPELIQSIHGEYINAGAQI
IETNTFGANRAKLEAHDLSEKVREINIKAAKLAIHAREIAGQSAFIAGAVGPSGRPLQAP
DEHRLNELRSIFREQIEALQAGGVDLIILETFSNLSELRQAVLAAKEVGDLPIIAQMSFH
EDAHTLAGQSAARVATVLRDLDVDVIGANCSVGPAATLDVLSEMIAAVKQTTEMNSSRPP
LFSALPNAGLPTRIGNRFFYVSTPDYFADYALRFAQAGVHLIGGCCGTTPRHIAAMRQAL
DEHYGKRAQFSGIATPAAESAKTNGKAIIAGVVEEEVILPQQGTRTRLQEKLAAGEFVVS
VELDPPMGLNPAKILEGAALLQKSGVDCINIADSPMARVRMSCMALARLIQDHLGIETII
HFTTRDRNLMAIQSELLGAHALGIRNVLALSGDPLRVADYPNTTGVWDIDSIGLIQVLRG
MNEGHSASDSSIGARASFHIGCALNLNMTDEEVEQEIEKYQKKLEAGAQFIMTQPIYELA
PLERFLKRVGKPPIPVILGCIPLHSSRHAEYLHNEVPGITIPDDVRARMKAAGDHGHEEG
LTLAQELLAEAHGYVQGVYLMPSYRRYDVVSELTKMLHTQHAAKP
>A0A1R0GPR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium mucronatum|TrEMBL
MHMTCVGTKIEQINCVLKTAKKKNLQNLLALRGDPPLSGNNVSIKPKGSDLSETSTFSDT
SSDASSSSPSKVPRGDIDQMNLKLAAKMRATGEFQNAEQLVKHIRNEFGDYFCVSVAGYP
EGCESCEDVDHDIAILKRKVDAGADFVISQLFYDIESYIKWIKNCQNAGINVPIVPGIMP
IQNYNSFKRMSKMCKFKVPEEIWTSLESCKEDDLAVKDFGIQYSIYMIKTLISHGVKGFH
FYTLNLERSTQLVLEGLELVPIINQPQINTFSKTSDTSTAACLELPSVTSHFFEKLVAFN
RQTKELPWEASHIDKRATENVRPIFWHNNASSYIDRTKNWDEFPNGRWGDSRSPAFGELN
YGQIWQYTRQQVIELWGAPISVDQLIQLFADYCHGKLMSLPWSDTQLLLESNEIKQYLET
LNKSGYLTINSQPSCNGINSSNLVHGWGPKNGFVYKKAYLEFFVSPEKCEKLLDVLDELN
SESQDSPVITYLAIKRDCKLKSNWNIAQPNAVSWGVFPGCEIIQPTIVDAESFMAWKDEA
FDYWKLWSDSYGSSTKYEKTAHFLTEIRETWYLMNIVDNNYTRNADYIYNILLSI
>A0A352JEZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudanabaena sp|TrEMBL
MIDLPQLIVEQPFHKFRKAIANQEFLITAEVSPPKGSDPTHMLAQTRSLKGRVHAVNITD
SSRAVMSMSPVAASFLIQQQIGIETVCQFACRDRNRIALQGELLGAAALGINNILALTGD
PVKAGDSPAARSVFDYESVRLLQLIQKLNQGIDANGKALPHQGTNFLAGAAVDPQSRSWS
GLQRRFERKINAGAQFFQSQLITDFDRLDKFVHQIANQSDKPVLAGIFLIKSAKNAIFLN
KYVPGVQIPDHIIDRLAKAKSPLQEGLAIAAEQIQTARQICQGVHIMAIKAEHLIPEILD
RAGVANL
>A0A1F8S9Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_70_13|TrEMBL
MAFLRRGGPATHLAPGPRAALAGLLESPTFELIPLRNALDQAAALPPGSTVSVTASPAKG
IEATIELAETLTTAGFRAVPHLSARMIRDRGHLRGLLGRLRDAGIDRAFVVGGDEEQPGD
YADGLALLLAIADLGNGPREIGIPCYPQGHAVIPDDALLRALRDKAPFASYMTTQLCFDP
PAIARFIAARRAEGVMLPVKIGIPGVAEIPKLMTISARIGVRDTGRFLLKNSRFVGQLLT
SGGIYRPTGLLEKLAPFIAEPRAGVIDLHVYTFNQVPSTESWRHDYLAALTATAGAAASA
>A0A2E8TLE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MRVNPFDQKDESFIFTAETTPSVSTNLNESVEKISSLIGIADAVNITDAPNCKTKLSSLV
VAGEIKKNGLDVILQITGRDRNSIALESEILGALSLNIDKILCLSGDRPPEDGPMAVNEM
NSSNLIELLNNMSAGNLLDGTEIKEHKKIYSGCADSIHDHYVRDTHSNFFVEKVRMGVGF
VQTQYCYDLDLCKKYSEFILENNLSDQAKFIVGLGPLKSAKQASWMRENLYGVKIPDSII
LRLEEASSPLDEGKKICEEIIQELIDLKGISGVHLMGPNCEDQCAELIKFFR
>A0A1V0U7M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces violaceoruber|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PEALKERILAAKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A124FUQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium 49_20|TrEMBL
AGGSQAQRDKTIEIASLILTTYHIEPVAHLTCVSLSRDEIIDTLERLKANQLQNILVLRG
DITPTMTVKEDFKHASDLAAFIKKYDSSFNLLGACYPEGHYQAESLEQDIENLKIKIDSG
VDHLITQLFFDNDKFYTFREKAERAGINVPIEAGIMPITNLRQIERTVALSGASVPAKLS
RLFSRYSDNPKALFDAGIFYATEQIMDLIDHDVRGIHLYTMNNVETATRISDAIQNVLEA
ENTPKNAA
>X1NX87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
TNFFAGAVVTPGADTEAKRELQLIKMEKKIAVGARFFQTQAVYDSNTFAEFTKRVEGFNV
PVLAGIIPLKSAGMARFMNKNVAGVFVPEELIDKMAKAEDRAATGIEIAAKLIKELKDIC
HGVHIMAIGWEKKVPAILDAAGL
>X1HJ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
GAAHLKSEVAKVKRKINVGVEYLQTQVVYYTDVLDKFFNELGKVDVPILVGIFPARTFGQ
ANFFHENVAGVDVPPDYLKNMKATKEIKDKEKRKEEVDRVNIEFFTGFLEHLKGTPAAGC
HMMAVGYPRIIAPLKKVME
>A0A0F9HD53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSDTPNRTAVAPDVSAEPATLREKLAAGRFVISAEVDPPHGLRTRKVLQGAAILKDAGID
AINVGDSPTAKVRMSPLAMSVLLQRELGVEIVMHYTTRDRNALAVHSDMVGAHVLGIRNI
LCLRGDPPSVGGYTDIVGVWDISAVGLMRSLKLLNDGVDWTGKPISGEADFFIGASCDPN
ADPLEPQLRLMRRKAEAGAQFFMSQNVFDEKVLEGFLDKAQRFGLPIIVGVLPLHNSRHA
EFLHKDVPGMQVPDAVRERMRRAGDEDGPKEGQAMARDFLAFCRERCAGVYLVPSFGRYD
LAAELVAEIKP
>U2NNK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium intestinale URNW|TrEMBL
MKTKKKPLIFDGAMGTYYSVLSKNPSTKCEFGNLYDRQTVLDIHKEYIDAGCGAIRTNTF
GANKEALESDFDVVKRVIKEGYEIAKEATKGTSVSVFADIGPIKELEGHELFKEYQEIVD
VFLDLGADNFIFETFSQEECLVDICKYIKSKNPKAFILVEFAVSPEGYTRLGNSGKKLID
KLSKITEIDALGFNCFSGPYHLLQYIKEFNIEDKTISIMPNSGYPTIINNRTFFDNSKEY
FASQMFEIAKLGVSILGGCCGTTPEYIKAMVLKLKELSLDDIVYDKISKPSEIKKSEVKN
KLIEKLDKGEKIIAVELDPPIDTEIDFFMSSAKKLKDQGVDAITIADCPIARARVDSSIL
ACKLKRELDITPIPHMTCRDRNINATKALLLGLNIEGVNNVLVVTGDPIPSAERDEVKGV
FSFNSSILANYITNLNETTFKSPFNVCGALNINARNFNAQMVQAKKKIENGITMFLTQPV
LTKEALENLKLARKELDAKILGGIIPVVSYRNACFMNNEISGINVSEEIIEMYKDISKEE
GTELAVKLSTQIAEEISEYVDGYYLITPFKRIDIISRIIENIKNK
>X0RZT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSKLQERLAAGEFVFTGEIGPPKGTNIEPCLHEAEKYLKDSVVAVNVTDIQTAVMRLGSL
VTCKLLKDRGIEPVFQMVCRDRNRLALQSDLLSAAVFGIENVLALTGDHIVMGDHQDAKP
>X0SYS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
LKDKVDALNVTDHQSSVMRFPSLGGCLAIKERGGEPILQMTCRDRNRLALQAELLLAHTR
GIRNVLCLTGDAVLVGDHKEAKGVFDLDSVQLLRTIHLMESGQDIGGNSLDGAVEFCAGA
IVTPEARPLEPQLIKFEKKVEAGAEFFQTQAIYDLDNFGKFMQHARQFPVKVLAGIVLLS
SARMAKYMTENVPGIFVPQDLIDELAGAPKGEALARGIEIAGRMITALKKDSICDGVHIM
AIGREEVVPDILAAAGL
>A0A518REZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas suaedae|TrEMBL
MSVNLDPSAPPLFADVAGDIDVSFEFFPPKTEKMEETLWESIQTLSPLNPRFVSVTYGAG
GTTRERTHNTVARIARETSIAAAAHLTCVEATRVEIDAVAEEYWAAGVRHIVALRGDPPR
AGEKYATHPGGYENAADLVAGLRKLHPFEISVAAYPECHPDSPDAAHDLDNLKRKIDAGA
NRAITQFFFEADTFLRFRDAAAGAGIDAEIVPGIMPVMSFAAVQKMSAMCGTDVPAWMAR
LFEGLDDRPAARQLVAATLAAELCRNLYAGGVRQFHFYTLNRAELSYAICHLLGVRPTAG
AKSVAA
>X1FD50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKLSELFDKGEFVVTGEVGPPKGANVDEVMEGAELMKDYVAAINITDNQSAVMRLGSLAV
ARLLIEAGIEPVFQMTCRDRNRIMLQSDLLSAEALGVDNVLIITGDHMILGDHPEAKPVF
DLDSVNLLAVARGLNEGHDMADEELEKPT
>X1N5U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
NSSFKKALESGKFVVTSEVAPPKGTNLEKMRHHIELLKDKVDAMNVTDHQSSVMRFPSLG
GVLLVKEMGGEPILQMTCRDRNRLALQADLLFAASRGINNVLCLTGDSVILGDHKEAKGV
FDMDSSQLLAAIRRLEKGKDLGGNDLDGNVSFCAGAIVTPEANPIEPQLIKFEKKIEAGA
EFIQTQAVYDLENFKKFMDYAKQFPVKILAGIILLTSAPMARFMNKNVAGVNVPQELIDE
MASAPKGRA
>X1LMH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKAGTNLEKVLESGRFAVTAEAGPPKGTSAAVVQRKGELLRHCCDAANVTDNQTAIVRMS
SLAGCVLLKQQGVDPVMQMVCRDRNRIAIQSDVLGAIALGIGNILCLSGDHQMFGNHPTA
KNVFDIDSIQLIQA
>X1LX78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MAKSLFEEKLNSGKFLVTTEIGPPKGADTSEIVHHIELLKDKVDAINVTDHQSSVMRFPS
LGGCLLIKEHGGEPILQMTTRDRNRLALQADLLLAYSRGIRNVLYLTGDSIDVGDHKEAK
PVFDLDSVQLIRMVRTMESGKDLGGHDLKGAPEFCLGASVHPAADFIEPQLIKFDKKVAA
GAQFFQTQGIYDLDTLHRLLPARP
>A0A8B7HUH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcebus murinus|TrEMBL
MDHREAKVLPAVHHCPSLGMWASEAGSVRFSVPPSIRNPAMVNEARGSGGLNPRSEGSSS
GSENSKDSSRCSTPGLDPERHEKLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRFD
RMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQDDITGH
LHKAKQLGLKNILALRGDPTGDHWKQEEGGFNYAVDLVKHIRNEFGDYFDICVAGYPKGH
PEAESFEADLKYLKEKVSAGADFIITQLFFETDTFLHFVKACANMGVTCPILPGIFPIQG
YHSLRQLVKLSKLEVPQKIKDIIEPIKDNDAAIRNYGIELAVNLCQELLASGLVPGLHFY
TLNREMATTEVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELSSEESVFDVFVRYLSG
EPNQNGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGWG
PSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTW
GIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYDEESPSRMIIQYIHDNYFLVNL
VDNEFPLDNCLWQVVEDALELLNRPTQSEREAEAP
>A0A1R1RQR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus haynesii|TrEMBL
MGFLEDIKSKTLIADGAMGTLLYSYGIDRCFEELNISKPEEIRRVHEAYVQAGADIIQTN
TYGANFIKLSRYGLEDETKQINEKAVRLARSAAGSAYVLGTLGGIRTFNKNSYSLEDIKR
SFREQLYLLLNEQPDGLLLETYYDLEEAREVLKIARKETELPIILNVSMHEEGVLQDGTP
LADGLKQLASLGADVVGINCRLGPYHMIRALEEVPLLEDAYLSVYPNSSLPSLVEGRLVY
ETDDEYFRESAEEFRNQGARIIGGCCGTTPNHIRAMAEAVKGLPPVTEKRVKIRKKAALA
VQNERTEPALDDLAKQKRSIIVELDPPKQLNFEKFLNAAEELKSAGIDALTLADNSLATP
RISNVACGALLKQRLDMRSLIHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRLE
KKIACGADYFISQPVYSEEQLIKIHEETRHLETPIYIGVMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGNDKQKQAEEGLAIARSLLDAACDLFNGIYLITPFLRSDLTAELTAYIH
QIEKEKTNV
>A0A6L8TGQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia massiliensis|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPGTIEHLMKYRPEYISCTYGAGGGNVGANRE
VCQMIRNAGTVPVTHFTVIKNTKEGIRQQLEQYLADGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A847ZEP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp|TrEMBL
MTHPLMNELGRTVLVGSGAIGTCLRKAGGRIDEPVELLNLREPALVRNLHAAYRDAGSQI
LVTNTFAANALILGEAGADDLCDDVNRAGVTLAREAGGAQCLVWASVGPLGLGLRLEDYP
DGALEEIYRRQCLALVEADALLLETFVEPREAKAALAAAAATGRPVIFQIGNTGGGGQRW
ERVDCLLAEARLANVVAVGTNCRHPNEIVRVAAYLAAHTDWPVTASANAGHPQIERGAVT
YEFSPDDFAAFALELADAGAAVIGGCCGTTPYHIRKLSEALRGRAVAPRPRPAAVAAPLP
AVAATAAAAANPIRALVADKRFLISVEIRAERTRSLDEIVQGAAAVAEAGADLFDVPDNA
GAAVGRDAMVTAARLQSVLDIPSICHLGVTQSNLMRLHSSLIGGWDLGLRGLLAVTGDAP
SMGHLGNLAQRVTDVRSSVELLRLLRGLREGRIINGEGLADPPDFCAGCAIARPIPPQIK
WLRAKIDAGAEFVFSQPVFTLDDSHRLQDALAGLPIRLFPGVMPLTSRRNAQFLAGGRIP
GIAVPPEVAAGFDRYESLQDQRRFGLDRACELAAGIAAEASGLYLIMPFGKSCYEDTARI
VREVKNR
>A4HQF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania braziliensis|TrEMBL
MSGLISDAIAAEDANKWYTSYEFYPPRSEKAEENFMKVQIPNFMRQSPVFLDLTWGAGGR
TSETTMRLCKDLQNAYPDTPINMHITCTNMSHDLIKETLDFAKEHGIRNILALRGDPPRG
DEFQSNPEGFTCARDLVRYIHATYGDYFCVSVAGYPEGHPSRIAEDGTILDEDHQKELEY
LKEKVDAGASVVITQLFYDASLYVKFVKDCREMGITVPIIAGLLPITTYAGFTRMVSLCK
TRVPGDVKKRVEELKENPEALKEYGVEQCVQMIERIRASGLDYHHLHFYTLNSSAQTFQV
LKRLNALVE
>A0A3M7G3P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMSYDAEIFVEWAKKVRAAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAELFVKYMSGKVETLPWSEQPISPESNVL
TNDLVNLNSRGLLTINSQPAVDGMKSSHPVYGWGPNNGYVYQKAYLEVLIPPSLIAEIIR
RMDANPDITYYAVNNSGELKTNAPQDGGPNAVTWGVFPGKEIVQPTIVETISFLAWRDEF
YHLGSEWAKCYDEGSRSKTLIKDITESWYLVNIVDNDFRNMRGIFPLFDGLKVDGVEPTA
AAVNGVAHVNGDANGDAEKKQGPLKPEVNGVPDKNNAVNHADGAAVNGQVKN
>W0VDZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium agaricidamnosum NBRC 102515 = DSM 9628|TrEMBL
MNACVEYKALPVPASHITDAYSLEVSAKDIAALSAAAPLILPASTISIPYLPREDNEARL
AAVQAVRRLGFEPMPHFSARRIASLAEFESFVERAVAEAGVKRCFVIAGDPSTPMGPFSD
SASLIETGVFERSGIKVIGVGGHPEGHPVMSTEAQWDVLERKCHSIVQRGMTPLIVTQFA
FDADIVLAWLKALRERGIDHPVRVGVPGPASIAVLARYAALCGVSACASMWSKYGVSIGK
LFGTAGPDLFVDRLASGLTAAHGKVSLHFFPFGGIAQSVRWVGEYRGRVEPAA
>A0A3P1ZUB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp. OH1186_COT-070|TrEMBL
MLRARKPRKEVFVHIGQMIASARTPFCSLEFFPPSDAAQMPDFYATVERLRALDPLFVSV
TYGAGGAGGRKTLSVTAELARRGFAVMAHLTCAGADAASLDAFLGELRSSGVCNVLALRG
DPPAGQPWDWNQGAFCHASDLVAFVRERQPDMGIGVAAYPAPHPESSSFAQDRRHTAEKM
RAGADFAVTQLFFDAREYEDLVAHLRGQGVTTPVIPGILPVQSFESLRRILSLCGANIPG
KLYLSLEKAHADGGAEAVREVGLAFAVGQIRRLLDCGAPGIHLYTLNRADLCLRLAQEAG
LA
>S2Y6Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HGB0020|TrEMBL
MLATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVKETEQ
IVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNILAVRGDPPGDPMAEWVQHPKGL
AYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVTTAGCRTPVIPEVMPVTSVRMLERLPQLSNAHIPSVLKERILTAKDDPAAV
RSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>A0A433N1Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorogloeopsis fritschii PCC 6912|TrEMBL
MTENFIVMLATRNPIPLTSFRAAAKAGEFLITAEVAPPKGGNPEHMLKMAATLKGRVHAV
NITDGSRAVLRMSSVVASAILLQHGIEPICQIACRDRNRIGLQADLMGAHALGIRNILAL
TGDPVKAGDHPECKGVFDLEAVRLLQVIQKLNHGIDCNEQPLSDGALDLFPGAAVDPQCA
SWSGLQTRFERKLEAGAQFFQSQMITDFELLEKFMDKIAAGCNKPILAGIFLLKSAKNAQ
FINRCVPGVNIPQHIIDRLAQAKDPLAEGVKIAAEQVQIARQLCQGVHMMAVKREDLIVP
ILEMAGVVPVSQMALR
>A0A4S2AWX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculum sp. NM65_B17|TrEMBL
MKVTELIASHGKTGFSFEVLPPLKGKGIAQLFRNIDILKEFNPLFINITTHRSEMVYKNT
PDGLYQKVSERSRPGTVAVAAAIQQKYNIPAVPHIICSGFSKIETEYALIDLNFLGITNI
LILRGDKAKHESRFIPNENGYSHASELQLQINEFNRGYFIDGTKMDIITGETFSYGVAGY
PEKHDESPNLDMDIAYLKQKIDNGAEYVVTQMFFDNSKYYDFVDRCRKAGINVPIIPGLR
PITTIGQLNILPKIFHVDMPMQLVSELMKCKDDNDAKEVGVEWCKAQCLDLMAHGVPSIH
FYSLNSTRSVERVAASIY
>A0A0M8MUP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escovopsis weberi|TrEMBL
MDKITDKIAALPADGQYFSLEFFPPKTAMGFSNLCARLQRMQRALRPLFINVTWGAGGST
AEKSMELARFCQREVGLTTCLHLTCTNMSRDLIDSALEEARALGIRNILALRGDPPRNDE
YGDVNGGDAAGGGNGGGVDGDEDEAVEFSWAVDLVRYIRRKYGDYFCIGVSAYPEGHASG
SHPEEQSLEYDLPYLVDKVQAGADFIMTQLFFDISAYDRFETTLRAHPSGAFKTIPIIAG
LMPIQSYAMIKRTTKLSHARMPEGLMARLDAAKGDDEKVKLVGVDILSQLVEQVRHVKSR
TPGPRGFHFYTLNLEKAVSFILERTKLIPDYAPETGTPDAAAAAAAAAVAVSDNAISAAP
PRPQVNGFGSTAAPRRSSHSRTGRRLSSVGSDPHNRVIVAGRDATYPEWEATTKEAGVPA
ESINTRLNTLAISEGEGTLGREATWDDFPNGRFGDARSPAYGEIDGYGVSIHMSVPQAVS
LWGRPTTPAHISDIFTRHIRGELSAIPWSEEDLVAESSIIQSKLVAINARGWWTVASQPA
VNGAPSSHPAVGWGPPAGFCFQKAFVEFFIPSADWAALLPRLTAPGVRDSVCFFAGNARG
GFASSDDGCHGPGEDGRPSAAAATAAGATPSTNAVTWGVFPGKEIVTPTIIEEVSFRAWN
EEAFDIWGEWARVYPRRSESHKFLNGIKDDYWLVNVIHHDFPQQDALWDLLLE
>A0A4Q1KLI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oerskovia turbata|TrEMBL
MSIVDLGHFGHEAPRPTVSFELMPPRRPDAAPKFWETARRLVATSPDFVSVTYGAAGTDR
ETSRRVISQLLHGTPVLPIAHLTCVGASREDVEDVITDFLDAGVRSFLALRGDPPRDQPD
WRPAEDGVRSSTELVALLREVEASRCAASPSVALRGAARPLTIAVATFPDGNLAAGTSRT
QEVRRLWQKQQAGADFAITQLFYEASSYIDFVAEARAAGVTIPILAGLLPMTDPARLARV
EELTGVPAPRRVVEALEAEPDPDARHALGIRHSVELARRVLAAGAPGLHIYTFNKHQAAL
DLLEGVDLGGGAAGDADGVSSRTPDLASGPWVSGTPLPSAEPALGSSSV
>A0A318U3X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter viridis|TrEMBL
MTTPNISFEFFPPQTLDASFRLWETAQVLAPLKPSFVSVTYGAGGTTRKLTHEAVAAIHK
NYGLNVAAHLTCVDATKAETKEIIDAYAEAGVTEIVALRGDPPKGAARFTPHPEGFASSV
DLIEWLAEDGRFTLRCGAYPEPHPEAADSFADVRWLKRKCEAGATSAITQFFFEAETFFR
FRDACVKEGITAKIIPGILPIQSWKGAKGFAQRCGTSIPTWVEEAFDHAIRDDREALLAT
ALCTELCDNLIAGGVDDLHFYTLNRPQMTRDVCHALGVNPDVVLENVA
>A0A1S9RJB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium brasilianum|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRALVDMALEEAKVLGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRKQHGDYFCIGVAAYPEGHPADSFQDVQDPVRDLPY
LIEKTQAGADFIMTQLTYDIEAYQKFENMLRNHESGVFKTIPIIPGLMPIHSYKILTRVT
KLSHVHIPDPIAKRMEELKHDDDAVKRAGVDIVSEIVGGMQELKSPGPRGFHFYTLNLEK
TVSFILERCDLIPASTDIEDDYAIVEADGIVPLGASARLARRRASSINSQPHNRVIVDKL
SSKVSSHDSVHEALANSVGQPAMPPGRGTTLQISEGLGSLGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTSAVARRIWGHPVEPSDISTLFRRHVSGELYMVPWSEGGAEEGTGL
NAETELIRPELLKLIDGRGWWTLASQPAVNGVCSDHHIFGWGPQREGFVFQKPFVEFFCS
SKDYDTILKPLFAKHGHDKLVWFATNNTGAFESSLPVQPADVELDDLNSNPESVNAVTWG
VFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTERFLDTTKNDTWLVCVVG
QQFGAGTPQGSKEEEDEVKWMWRVLAGETQ
>A0A1X0VJL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas graminis|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDGKEDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VQFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITRMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1B6NYA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNELSPAYFSVTYGAGGSTRSRTLDIVQALSA
RSETEIAPHMSCIGDDKAQIAELLEFYKSLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFEFDVDNLVNKYRAGANASITQFFYNADSYLYLR
DTLEKRGIDTIAQPLVAGIMPITNSSNLIRFADSCGADIPRYVRKRLADFGDDSKSIREF
GFDVVYRLCERLMCEGVPAMHFYSMNKVEPNKRLVEALGLTV
>R6MR01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:443|TrEMBL
MRVIDLIKSPEKTAFSFEILPPLKGTGIEKLYETIDSLREFDPKYINITTHRSEYVYREL
GNGLYERKRIRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREDTEYVLLDLQFLGITDL
LILRGDKAKHEQVFTPEPGGYAHAVELEQQINDFNRGVFVDGSPIKAPVHPFSYGVACYP
EKHEEAPNMEQDIYWLKKKVEAGAEYAVTQLFYDNRKFFDFVDRVRREGIDIPIIPGIKP
FSKLSQLSVVPKTFKVDLPQDLALEALKCKTDEEARQLGVEWCINQCRELIAHGVPSIHF
YTVGATESVRRVAKEIY
>A0A6J0RH83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bactrocera dorsalis|TrEMBL
MALKTPPNCERTKAFYATLKSSAISLHRSERIQLFEKLFVNQIAIACGYGRTTKVPLTQN
QKKISILNQNLRRSDIRIQKTMHNPDYVPATNCCNATTSICGGHVPLPTAPEFHPVYVRF
SSKQQAPEQRKLAELFKQKVAAKEFFYGIELTARSYGKQPSLLDYNGFDVLLPLFTSLVW
LGRDYANVEDVNAIEAISLGRQLQPHVVVMPHFTCYRADSRRLDDFLTLNFTNVLALRGD
DVVPQQQFQHAKDMVEYIRSKRGDTISIGVAGYPDGHPESKSLDEDMQYLKEKVDAGADF
IVTQICFSPESIISFVQKCRKMGITVPIIVGVIVPDNMRILQFIMNIVKAVIPEEQLSKY
KELEGDRKAFKAYAVENAVRTVQMLLDSNLDVYGFQFFTMNRLKSVQQVIQQILNMNQTQ
ST
>A0A2E1AB72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MNETIQTKLAFRERLALPKPLLTDGAMGTILQQRGNLRISACFDELNLTQPDLVRSVHVD
YLRAGADIIETNTFSANRIKLAQFNLANHVRDINKAAVAIAHDALVEAGREHDAYVAGSL
GPLGEGIAPFGTISEADAHTAFHEQIQALVDAGVDLMLFETFANDDELLIAVEEAQAIAP
ELPIVAHATFSRDSRTYLGRTPARVAQALYKKGVTVLGVNCGGGPAHISELIHAMHEAVP
NALLSAMPNAGYPQAMGGRVMYPAEPAYFGETAITLQAQGAQIVGGCCGTTPEHIAAMRV
ALDDETRVATVAIVEQPDDVDTGEEDLRPTLLQERLKNNEFTVTVEMAPPRSYTAEKLMN
NARLLTDAGADMLNVADTPAARMRMSAWAVAHLLQHKLGLETVLHFPTRGRNSLRVQGDL
LAAHALGLRNIFITMGDPARIGDFPDATDSFDIAPSRLIGVVKQDMNQGRDLGGSSIGRP
TFFTVGCALNMAPDNLDREMKVLAKKLESGADFALGQPVFDPPKLDAFLEAYEKTFGESF
KLPVLMGIMPLYSLKHALYLNNEVPGINIPQTILKRIEDAGDDAAQEGVNIAIELAEQMR
DRVQGAYIIPAYGRYKLAAQVVAAVTG
>A0A853QJZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKYEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFEHFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQVKSFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAKEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
SGKEFSPEISRFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKSVGRFIFKASFWENALVAK
VLIKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKEKLIPTVPLETRGTSSWKNWYLTTEA
>A0A6G3Q6E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID12488|TrEMBL
MTTFSFEFFPPRTTKGERTLWDAIRRVEAHHPEFVSVTYGAGGSSRDRTIDITRRIAAET
TLRPVAHLTAVGHSVAELRHIIGMYADAGIRDVLVLRGDPPGDPRGRWTAHPQGFTYAQE
LVELVRSLGDFTIGVAAFPERHPRSADWESDIRHFVAKCCAGADYAITQMFFRTEDYLRL
RDRVAAAGCDIPIIPEIMPATDVRQIRRFAELSGATFPEDLAHRLEAARDDPVAGHRVGV
EHATAMAERLLGEGAPGLHYITLNRATAALDVHRNVQTSRSLSGHGLR
>A0A419EDZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MKQPGWMRRSHTRSSATIPCWLLSKNLERETMNLLETLNKKTLLADGAMGTMLHARGIGF
DKSFDELNLTDPAAVADIHREYIEAGAELIITNTFGANKYKLSKHGLEDDVAKINRAGVE
LAKRVVAASFKDVLIAGDVGPLGVRIAPYGRVKLEEAREAFVEQIKALAEAGADLIVIET
MSDLYEIQEAIKAAKEVCSLPVVASVTFTRDDRTLLGDDPAKVARRIADAGADVIGVNCS
GGPSQLLRILKQMRQAAPNGRFWVKPNAGWPEQVGGRIMYPADADYFGDYALSFREAGAN
IVGGCCGTTPQHIAAMKKALDAAPAGKIADITVLPEDEISAEPAEQPTQFAQKLANGKFC
ISVEMDPPRGLSTHKLLAGASLLHDSGADVINVADSPMARMRMSAWAVCDVVQRTVGVET
TLHFPTRGRNLLRVQGDLLAAHAIGLRNVFVVMGDPTSIGDYPEATDNYDLVPSGLIKLI
KQGFNMGVDHSGTSIGQPTNFFVGAALNLCPQDMDTEIKNLRRKLNAGADFFLTQPIYRT
DDGPKLIEAYQAKHGKFDKPILAGILPLVSAKHASFLHNEVPGVFIPDEARARIEAAGED
AAKVGVELAVELIEGIKGWASGIYMMPQFHRYDMISDIIMAVKE
>A0A6N7ZPP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium sp. RKSG952|TrEMBL
KDRVLRRSLMNIVHEQVINPVNRGSTNFHFYTMNRSDPTYEICRMLGIGHAEFEKTNA
>A0A1M7Z0N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio quintilis|TrEMBL
MGYSHASHIDALNQNIAELSDDINVSFEFFPPSTPKMEETLWNSVHRLKDLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLVAAPHLTCIDASREELIHIADDYWENGIHNIVALRGD
IPPGGGHPDMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKIEAGANRA
ITQFFFDIECYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAMNHVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPVQTV
>R5ZWA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium eligens CAG:72|TrEMBL
MKYTGTAGILYDRLKSEILVADGAFGTYYAKKYDTGSLPELANLQASDRVLAIHKEYIEA
GAKIIRTNTFASNTVCLGAGFDEVRNNIKNAVDIAREAVKGTDVLVAADIGPIPGENMIE
KEHIEKEYVDIVNVFKECGVDIFVFETFPELGFIDKAIENAGENGFVITQFAINQFGYSS
AGFSARKLIEEAEKNSYIDACGFNCGVGPGHMKKLVQSLINRNDKYFAVLPNAGYPQVVS
GRMVFDDNNAAYFSQIMHDLAEDGADIIGGCCGTTPEYIRQMVLKTADVVHKKNASIEEE
ITEKKTANDVSFYKGKEGRKLIAVELAPPLGIDDEKIMDAAFLMKESGVDVLTFPDSPSG
RTRADSILMAEKVSRETGMCVMPHICCRDKNAIAMRSQLLGAHINDINNFLVITGDPIPS
VVRASVKSVFNFDSVGLMNIISDMNQEQFAGEPVIYGGAINQGRVNFKVELERVKKKMEA
GATFFMTQPVFSDEDIDRLRQIKEQTGARILCGIMPFVSLRNATFMKNEMTGINVTDEIL
SRYRADMSKEEGEETGIQIAREIIAKTTDFVDGYYFSFPFNRVHMLKKIIGKNNQ
>A0A3G6YMK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIDKVLHFSGK
ARDIQDFEHFLEQAQAANIQNLLLLTGDKLKEHHHGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKH
LGFSGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVTSGKEFSPEITYFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENSLVAKVLIKTEVLSKHSLV
GCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVEQT
EILKEKLIPTVPIETRGTSSWKNWYLATEA
>A0A1A8HHY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius korthausae|TrEMBL
LKNIMALRGDPVGSDWEEEEGGFNYAVDLVKHIRSEFDDYFDVCVAGYPTGHPEAESYED
DLRHLKEKVDAGADFIITQLFFRADTFLTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLV
KLSKLEVPEEITRVVEPIKDNDAAIRNYGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAP
TEVLRQLGLWIEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRW
GNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEELKREESVFEVFTCYITGQLNRNGHK
VMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTDAVVGWGPAGGYVFQ
KAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAHEMQPNAVTWGIFPGREI
VQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLE
SCLWRVLDDMFELLDAPLETLADGMPGDGSHDDGTLAE
>A0A0K9PRW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zostera marina|TrEMBL
MKVIEKIREAVEGNGQTVFSFEYFPPKTEEGVENLFERMDRMVKHNPTFCDITWGAGGST
ADVTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALTTIKNNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHMRAQYGDYFGITVAGYPEAHPDQIQGECAAHDAYQNDLVYLK
QKVDAGADVIVTQLFYDTDIFLKFVDDCRQIGITCPIVPGIMPINNYRGFIRMTGFCKTK
IPAELTAALEPIKDNEEAVRAYGIHFGTEMCKKILASGIKTLHLYTLNMEKSALAILTNL
GLIEESKITRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTVGWEQYPRGRWSDSKNP
SYGALTDHQFLRPRSRDKKLQKDWAVPLKCVEDIYERFANFCLGILSSSPWSDLEGLQPE
SKIIDAQLGMINQKGFLSINSQPSVNGEKSDSPSIGWGGSGGYVYQKAYLEFFCSEEKLK
SLVEKCKSIPSLTFTAVNKDGKSITNIGDPSEVNAVTWGVFPGKEIIQPTVVDPDSFMVW
KDEAFELWTKAWACLFPDGDLSKQLLEQVQKTYFLVSLVDNDYVHGDIFAVFKDL
>A0A2S5DGK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium sp. MWU14-2602|TrEMBL
MTQPRTFSFEFFPPKTPEGIAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEIR
SEGQAAAPHLSCIGSTRENIAAILNEYRSNGIRHLVALRGDIPSGMVAAGEFRYANELVE
FIRAEHGDHFHIEVAAYPEFHPQARSAEDDLANFVRKVRAGADSAMTQYFFNADSYFRFV
DEIRARGVDIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRLRMQAYYDDAASIRALGLD
VVTELCDRLLQGGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A0B4D3F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter phenanthrenivorans|TrEMBL
MSPPSLSDAHPNLSDTAPVALSYELFPPRSPAAAETLWTTIRELETTGPDYVSVTYGASG
SNRNTAVDLINRLLRETTLRPLAHLTCVGNTPQELAAIVGELLDTGVRGILALRGDLPKD
ASAPAAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEEHDVEVLL
AKQRSGADFAITQVFFKTEQYADLLARARRAGVTIPIIPGVMPLTSLRRLRRLGELTGVE
PAAELMERLAAADTDLERLHIGVDATVDLANAALDAGAPGIHIYTFNEHQSALDVLDKLA
LPRHSRNGSRSTTRAGSPSWTQPAPASASFSSS
>A0A364WG79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter rubeus|TrEMBL
MKIPEHIANANGKTLFSFELIPPLKGQSIQGIYNAIDPLMEFKPPFIDVTTLREDFIYKQ
HPSGLLEKLSYRKRPGTIAICAAIMNRYKVDTVPHLLCGGFTKDETENALIELEFLGIEN
VLVLRGDARLGDSSFVPTPNGHCYATDLLQQVVNLNNGIYLHEDHGNTAKTNFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVEMGAQFIVTQMFFDIGKYKEFVNGCRANGINVPIIPGLK
PITSSKQLVTLSKTFHIDIPEDLSDAIHACATEKDVKEVGIEWMIKQCKELIAFGAPVLH
FYTMSNAGPTKRIAEAIF
>A0A1H0R3E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nakamurella panacisegetis|TrEMBL
MPVCIADKLHRMVTVRERLAAPGPHFSVEFFPPRDDAEESTLWLAIRKLEPLRPAFVSVT
YGAGGSRRDRTIRITERIAAETTLLPVAHLTAVGHSVAELRHVIGSYASVGVRNILALRG
DPPGEDPSAEWIPHPQGLNYASDLVALTCSLGDFHVGVAAFPDMHPRSPDLESDTRYFAE
KIAAGAEYAITQMLFSAQDYIGLRDRALAAGADVPILPGIMPVTSYARLMRIIELSGQRI
PTDLAERLLAVQGDAAAGREIGMQHAIQMSHQLLAEGAPALHFYTFNRSKATLEVLAALG
MAGTPDREPALQT
>A0A117S984|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BRH_c32|TrEMBL
MKVIEHLEKAKETLISFEIIPPKRGGDIKQLLSILEDIVKYEPPFIDITSHAAEAYYEET
SSGTFNIKIKRKRPGTLGICALIQNKYNIDAVPHVLCSGFTREETEDFLIELHYLGIDNV
LAIKGDDHGFKKPLKFGRSANDYALDLVKQINEINNGKYIEDSILDSYPMDFCIGTSGYP
EKHFESPNLSTDIKYTKAKIDAGASYIVTQMCFDNKFYFDYLDTCRKSGINVPIIPGLKI
LTSKNHVTSLPKNFFIDVPSELAEEVSKAKPEHVLEIGIEWTYRQVEELLNKNVPAIHFY
IMQNSEPIKKLMKKVGM
>A0A428LFV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter huaxiensis|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRAIAQDYWNNGIRHIVALRGD
LPPESGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A3C0EGZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MTRQTCSDGRTVAVRFEMFKVVPQNTVMHTSSIQVDSNSPSTQCPKRLCRGPCSDTLDGR
CGTLPEQDCVWLDGPVIETRHHMSTTPQAVGDRAVVSKLQKRLCDGAFVHVCEIHSPKVG
QLGCFVDRALALSPWFEAMNVTGQLKGRSVMPSPEAAGHLRAIGVDAIAILTGRDGDQTQ
LLTELAMMHCSDVGNLMCLTGDGGQGHAEAIQMDSLGMLRLASGEPASRRLWLGAVINPF
STPATLPLLQLEQKIESGADFVQTQMVFDLPRFEAFCDAMVARRLHERVSLLAGVPVVVS
QEGLALVKRLPGVWLPGAVEKRLRESSDIRQCGIDLAKQMIASMRKMLGVRGVHVMLLGG
EDVQDMIEVVQP
>A0A3C1J3J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MGNTTHTKEQIRERIQQKKLLFDGAFGTYYGGKYDTKQLPELANLEAPERVREIHTEYLE
AGAQILRTNTFAANSFCMDRPKEQIEETLRSGVRLAREAVAAWRERTGETKEVYIAGDIG
QIPGDALAQKDTLCSEYKEICRIFLEEGVDFFVFETFSEMEELLPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGEVKEIDAVGFNCGVGPSHMHRILQILEKPEGKLLTALP
NAGYPQMVTGRMLFTGDNKDYFVDRMQQMTALGVDMAGGCCGTTPEYIAELAGKLDLTQY
PQAKKDTEPEKQQAPKEDRSFYHTKEAEGRNRKLIAVELAPPMGIDDEKLMDAAHLLQRS
GVDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGI
QNFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFTQAPASYGGAINQGRRNL
EVEIGRVKKKMAAGATFFLTQPISTQESADRVRRIKEETGARILCGIMPFVSLKNATFMK
NEMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVIVMTEDFADGYYFSFPFNRVTMLE
KILN
>A0A6I4W391|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura rayongensis|TrEMBL
MPIVRPDRAPTIRELLAAGGRTFSFEFLPPKTEQGMRNLWRAIRDLEPLGPSFVSVTYGA
GGSTRDTTVDIVERIATETTLTPVSHFTAVNHTVAELRHLVGRFADAGVRNILALRGDPP
GDPLGEWVKHPQGLEYAAELVRLIRSYGDFCVGVAAFPYKHPRSPDIESDTRYFIQKCRA
GADYAITQMFFRADDYFALRDRVAAAGGDVPIIPCVMPVTKLSTIERSEQLSGAPFPPEL
RARFEAVAHDPESVRRLGVEHAAEMCRTLLDQGAPGIHFVTFNRSTATREVYELLEADRY
AASGSAPPITA
>A0A1G1A5U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium RIFOXYC12_FULL_60_16|TrEMBL
MFRDALKHDEFVITCEFVPGRGKEGASVDAALGFAREVGTSGPRIHAVSLTDNPGGNPAI
MPDALAPAIQACGLEAIVHFSCRDLNRNAVESRVMALSRAGVNNLLVVTGDYTSGGFEGN
AAGVFDLDAVQAIKYVKAMNAGLEVPGAKKGTTIRLPSTDCFVGAAVSPFKRSEQELMPQ
FFKLEKKIAAGADFVITQLGYDMRKFLEVKRYVDSRGLRVPIIGNVYVLSLGAAKTMHAG
LVPGCVVTDDLLRVLEAESRDPDKGKGKRLERAARMVAMFRGMGFQGVHIGGFALKTQDF
RFIVERAAAIAPHWEEFVPEVSFSRDGEFYAFPPPPSYRPAPPDADPVPSFGRGRRSLKY
TFARGMHRAVFDRRGLGCRLMTRYYRAIGERSIMARASHFAEYLLKFLTFDCRDCGDCAL
PDMAYCCPQGKCAKQQRNGPCGGSRDGMCEVFPDDRRCVWTIVYDRLKHVGRLDELRGRY
TPPRKTELQYTSAWANYYLGRDHGAGATTPALGTEPKGPTA
>A0A7C9KLJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polymorphobacter fuscus|TrEMBL
MAEAACALNPPLYADLPGDVAVSFEFFPPKSEAMEATLWQSVETLAPLAPRFVSVTYGAG
GSTRERTHATVARIAGETAIPAAAHLTCVNASRDEIDAIADGYWQAGVRHIVALRGDPPV
AGGRFEARADGYASAAELVAGLKRLHDFEISVSAYPEVHPEAGSLAADLDAFKAKLDAGA
SRAITQFFFEPETFFRFRDAVAAAGISAEVVPGILPVSNFAQLQRMAVPCATNVPKWMAH
LFAGLDDKPAARQLVAATVAAELCRRLYAGGVRHFHFYTLNRAELAYAICHMLGVRPSAP
ALEVAA
>A0A6N6VK60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvibaculum sedimenti|TrEMBL
MSGQDTKAEAARTSVSFEFFPPRTPEMEENLWRAIRRLEPLRPEFVSVTYGAGGSTRERT
HATVKRIVQETTLAPAAHLTCVGASRDEVNEVIRSYWEAGVRHIVALRGDMPELGATYRP
HPEGYQSTPELVAGIRKIADFQVSVSAYPEGHPESPSFEADIELLRRKVDAGATRAITQF
AFDTERHARFLEAVRKAGIDVPVIPGIMPTTNFRGTKRMAERCGASIPKWLDDYYIGLDD
DLETRKLIAAYVAAEQVNRLRAYGFDRFHFYTLNQADLTFAICHVIGLRPERVAAPVA
>A0A415FEP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF46-10NS|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVQLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAEI
>A0A4Z1KG73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrytis porri|TrEMBL
MEKITEKIAALPPGTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRAIDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDGFEEKLREHPSGAFKNIPIIPGMMPIQSYQMI
KRTTKLSHAKLPSTIITRLDAVRGDDEMVKKVGVDILSEMVEHLKSTKSQYSGPKGFHFY
TLNLEKAVSFILERTQLIPDAETVAALEPEYVPTIPDIADLVSIHSGSHKRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATALEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPGSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGPKNGFVFQKAFVELFL
PTADWITLQAKLTSPELRDIVSFYASNAKGDFISSDKAVGSTNAVTWGAFPGKEIITPTI
IEEISFRAWTEEAFGIWGEWARVYGKDSQTRKIIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLN
>A0A2R6S0G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinidia chinensis var. chinensis|TrEMBL
MKVIEKIREVVGTENGGGADKVVFSFEFFPPKTEDGVDNLFERMERMVAHNPSFCDITWG
AGGSTADLTLEIANRMQNMVCVETMMHLTCTNMPVDKIDHALQSIRSNGIQNVLALRGDP
PHGQDKFVQVQGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDVIQSVGVATPEAYQN
DLAYLKRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMT
GFCKTKIPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKIMASGIKTLHLYTLNMEKSAL
AILMNLGLIEEAKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWEQYPRGRW
GDSRNASYGGLTDYQFMRPRTRGKKLHEEWAVPLKSVEDIYERFLKYCLGKLKNSPWSEL
DGLQPETKIINEQLGNINSKGFLTINSQPAVNGAKSDSPSVGWGGPGGYVYQKAYVEFFC
SRLKLDDLVDKCKDFPNLTYMAVNKEGSWVSNTTLHEVNAVTWGVFPAKEIIQPTVVDPA
SFMVWKDEAFEIWSRAWAQLYPEGDPSRKLLEEVQSSYFLVSLVDNDYVNGDLFAVFKD
>A0A5E1AKW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter kobei|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATGDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1Q9LT66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinokineospora bangkokensis|TrEMBL
MTTVADRLRTDRPVFSVEFMPPRDEADEALLWRAVRELEGMDPAFVSVTYGAGGSSRDRT
IRTTGRMATETTLVPMAHLTAVDHSVAELRNVIGWYAAHGIRNVLALRGDPPGDPNGPWV
QHPQGLNYAYELVELLRSLGDFCVGVAAFPYGHPAAADAEADIDNLLRKFDAGADFAICQ
LFFEPEDFLRFRDRVAARGCDKLLIPGIMPLTTPKMLAKTVELSGAPLPDRLAARLQPLA
EDAKAFRAEGIDVITETSRRLLAEGVTDLHFYTFNRSKATREVVGRLGLVPARA
>A0A239R5Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIIDILNKRNMSLSFEVFPPKKESTFESVVAATEEIAACHPAFMSVTYGAGGGTSRYTM
EIAKNIKDKYNVPTLAHLTCVSSSREAVHQKIQEMKEMGINNVMALRGDLTPELEESDPS
TWDYKHATELVRELKEAGDFCIGVACYPEVHPESINQKDDLLHIKDKVDAGADFLTTQMV
FDNNLFFNFMYKIREIGVTVPVIPGIMPITNANQVARAIKLSGSFMPQRFKSLVDYFGND
PDAMKQAGIAYATDQIIDLYANGITNVHVYSMNKPDVAKSIMDNLSNILGKDFAR
>V7G848|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNJC394B00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMAARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTIKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A318J3S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Undibacterium pigrum|TrEMBL
MKTPNFSIEFFPPKTAEGTEKLRVTRAKLAELNPKYFSVTFGAGGTTQQGTLDTVTEIRR
EGHDAAPHLSCVGGTRESIRAILNDFKANDIRRLVALRGDLPSGYGMGGEFRYANELVEF
IRAETGDWFHIEVAAYPEMHPQARSPQDDLNSFVRKMQAGANAAITQYFYNADAYFRFVE
EARKAGVTAPIVAGIMPITNSTQLQRFSEMCGAEIPRWIRLKLASYGDDTASIKAFGLDV
VTAMCERLLAGGAPGLHFYSLNQAAATTAIWQRLV
>A0A6M1PME5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus apii|TrEMBL
MKPDLRSAWASKVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVVEEVHRSYIEAGAEV
LESNTYSANYDKLSKFGLESKVEEINRAGIRIARQAAGSAGYVVGAVGSIRAGKRANLSA
SELKKYFSQQIGAMLEENADGIMLETFYDLEELHLALRTARKLSDLPVICQFAVDETAMT
MDGLTLPEAFRILEDDGADVIGFNCRTGPIGIKRALGTLQGSLNLPVSVYPNAGLADYVD
GHYKYGASPEYFGQMARDFAGMGSRIIGGCCGTTPQHIAEIAAALKGYEPLTLTAPEPKE
KISVRIHENLADDFEAEGGEPSLIDIVKERHAVIVELDPPRDLDISKFMAGAEALRRAGA
DALTLADNSLAVCRMSNMALGALVRQKTGLRPLVHIACRDRNLIGTQSHLMGLDALDIDH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKANFVIGAAFNP
NVKHLGKAVERLEKKIAFGADYIMTQPVYDPELIHKIADATAHLNIPVFIGIMPLASGRN
AEYLHNEVPGIQLSGEVRERMKGLEGEAGRAEGVAIAKELLDAATERFNGIYLMTPFMFY
DMSVQLLNHVWAKSGRQLSPLFR
>A0A6N4QLC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira kanakyensis|TrEMBL
MNKILLEVIPRDVPTLLGEVSYVKNNFSQISGINIPDLLRFETRSWVAASKIQDIFPNVI
PHLRAIDFDLDHCDRIIEFLQKHSISSVVVIKGDPPTDMSRKVYQTTSTKLIKKLKKEMS
SLKVYAAVDQYRSGIKDEFDYIEMKIDAGADGFLTQPFFDLRLIDIFTEKLRGKEVYIGI
SPVTNEKSQSYWESRNRAYFPRDFQLTMDWNVKFAKEVIGYCSQYDFNTYLMPIRINIEV
YLSENGMKLILNYYDF
>A0A7U9DGP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. KTE159|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPSGSGKPEMYASDLVELLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A250JCF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cystobacter fuscus|TrEMBL
MKIRNRLNPSSPCFSFEFFPPKTDAGTANLLQTLEDLAPLEPGFVSVTYGAGGSTRDRTV
DLVTRIKRDTGIEAMAHLACLGHTREELRELLRRLEEAKIDNVLVLRGDVPQGASPDTLA
NTDFRHAADLVRFIREEDFDFSLGGACYPEGHVETRSRDEDLLHLKAKVDAGLDFVITQL
FFDNAFYFDFVERARRVGINVPIVPGIMPITNHEQIQRFTRLCGATIPMRLALQLEQLKD
QPEALVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRART
>A0A7L1JF56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rynchops niger|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVCMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A731NB55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 42:r:-|TrEMBL
MSFFHANQREALNQSLAEIQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3R6PEC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. AF16-5|TrEMBL
MNILESLKDKLLVADGAFGTCYVGMYGEQGTVAPELANMRHPERVLEIHKEYVKAGAGLI
RTNTFAANTASLDADTDYVISNVRAAVKLAKQAAEEDVEAADCVRTSDAVVTEADESGTY
RKKVSVAGDIGPIPADAGLTLNERVSQYKLLGEAMQDMGVDIIWFETFPEFNVLEPVVKH
LKARKNTPVMVSFCVNQFGYSNCGFSARALLSQVAGNQDVDCVGFNCGVGPYHMLQLLKK
LDIDCGKPVSVMPNAGYPKFTQSRLVFNDNKEGFIDKIQDIAALGADIIGGCCGTNPEYI
HQIMERVKTGDIAKAAKVHVEKVQADSAVKDNFLKGRLERGGAATKNADGHKHKLIAVEL
APPVDVNDQKLLDAAHILKQSHVDVVTFPDSPSGRTRADSILMAEKVHKETGLRVMPHLC
CRDKNAIAIRGSVLGSQLNGIKDFLVITGDPVPVMFRQTTRSVFNFDSVGMMKLLQSMNE
EVFSGDKITYGGAINQNRLNTKFEIDRIKRKMEAGAEFFLTQPVFSREQAQILRDMKAET
GATILVGIMPLVSRRNALFMKNEMSGIEIPDEIIERYSENATRQEGEECGIQIARDILEY
TSDFADGYYFSFPFNRVHMLAHIVD
>A0A7Y2AA14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVIEHLAKADRTLISFEILPPLKGQGIQSIYDAIDPLMEFKPPFIDVTYHREEYVYKKF
PNGLLEKRTTRKRPGTVGICAAIMNKYNVDAIPHIICGGFNREETENALIDLNFLGIDNV
LALRGDQIKSESVFEPEPGGHAYASDLIKQIIDMNKGKYLDEELGNVASSNFSIGVAGYP
EKHFEAPNFKNDLRWLKKKVDLGADYIVTQMFFDNQKYFDFVDRCREMGITVPIIPGIKP
LTTKKQLTVLPKIFHIDIPEDLADAVADCKDNDAVKEVAIEWGVQQAKELIASGAPCLHY
YTMGKPAVTKAIVSKVL
>A0A7Y7J7G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium Scap17|TrEMBL
MSASEHPLGISFEFFPPNTEAGREKLKGVRDQLAALEPEFFSVTYGAGGSTRERTFNTVQ
SVSASGICTAPHLSCVGSDRGELREILAQYREQGVKRLVALRGDLPSGMGSRSELRYANE
LVEFVREETGEHFEIAVAAYPECHPQAGNYHSDLENFARKMQAGADIAITQYFFNADAYF
HFVERARAAGIEQPIIPGIMPITNYTKLARFSDSCGADIPRWLRRQLESYGDDSESLQAF
GTEVISRMSQRLLDGGAPGLHFYTLNQAEPCLKVLENLGIASR
>A0A6N9SQ46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrovum sp|TrEMBL
MNHAHYERVFSFEFFPPKTAEGAEKLRHTRRQLAQLNPAFFSVTYGAGGTTQDRTLETVV
EIQQDGYPAAPHLSCIGATRDSLRQVLALYRHHGIRHLVALRGDLPSGTLGGGEFRYASD
LVRFVREETGDHFFIEVAAYPEVHPQAHSAQEGIRHFQEKVEAGADSAITQYFYNPDAYF
SFVEDCGAA
>A0A350NUB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKITHHLEEAKSTLFSFELLPPLKGENIQKIHSTVENLLEFNPAFVDVTYHREEFVYHEV
TSGLLQKRTVRKRPGTVGICAAISHKYNLDTVPHIICGGFTKEETENALIDLDFVGVDNV
LLLRGDAIRSEGRFKAEADGHAYALDLLNQVAAMNKGRYLDPDLKNTNATDFCIGVAGYP
EKHFEAPNLESDLRWLKRKVEDGAEYIITQMFFDNDAYFDFVSKCREQGINIPIIPGLKP
LSTKGQLSSLPQNFHVNMPDELVRMVENAQSKEDVKEAGVLWCIQQAKALKAAGVPCLHF
YTMGKAEPTARIAREVF
>A0A140GW96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoplanes sp. Z2-YC6860|TrEMBL
MLETGQKLENNRLMPMLRDKLATDRFVITAEIAPPVSCDAADLMAKAAPLKGHADAVNVT
DGAGARAHMGAVGAAAILLQEGIEPILQLTCRDRNRIALQSELMAAAALGVRNLLLLKGD
DPKQGDQPDAKPVFDYDTAALTAVAVAIRDKGELPTGKKVSGKAEFFIAAADVPIDPPAG
WEPKSLKAKLAAGCEFVQTQFCMDASVVRRYMARLAEHGVKVPFLIGISPLRSAKSARWM
REKLFGTIIPDATVARLEAASDPAAEGRKLCLDLMKELATIPGVAGVHIMAPGNEAAIAD
VIKVAAGLKRAR
>A0A651F790|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MTIIEKLNKSEGKTLFSFEILPPLKGDTINSVYENVDPLMEFDPAYINVTYHREEIVLKP
AGNGLLRKKIIRKRPGTIGLCAAISARYKVETVPHLLCGGFSREDTENALIELDFLGIRN
VLALRGDSVKGQRHFMPEPYGNAFAVDLVKQITDLNNGIYIDEELENKHATNFCVGVAGY
PEKHFEAPSLNIDIQNLKAKVDAGADYVVTQMFFDNASYFSYVEKCRDAGINVPIIPGIK
PFASKRQLSILPTMFHVDLPDALALEVLKSKSNESVRQIGIEWAIEQGRELLAAGVPALH
FYSMGRSENIRNIAAQLF
>A0A443ZZ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas alkylphenolica|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKEDLRSLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHIEIAAYPEMHPQARNFEDDLNNFVRKAKAGADSAITQYFFNADSYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITRMSEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A3N1SRB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 840.1|TrEMBL
MLATGKTLHSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSVTYGAGGSTRAGTVKATQD
IAAESTLTPVAHLTAVNHSIAELRNMIGQYADAGIRNILAVRGDPPGDPMGPWVEHPQGV
RYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVDKCRAGADYAITQMFFDPE
DYLRMRDRVVAAGCDTPVIPEVMPLTSVRQLERFAQLSNATLPAALKERILAAKDDPAAV
RSIGIDFATRFCAKLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A0N1L2R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. AAP116|TrEMBL
MTHIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKVF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGAQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMAKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDHVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGILKGRRPWKREHGRADDIAAQRMREIGADPVQDQQTLAGLAA
NTQPH
>A0A543GEU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia cypriaca|TrEMBL
MKVTQRISGERPVFSVEFFPPKDEAGEAELWRAIRRLEPLDPAFVSVTYGAGGSNRDRTI
RTTARIATDTTLVPMAHLTAVSHSVAELRQVIGAYAAAGISNVLAVRGDPPGDPLGEWVP
HPQGLTYADDLVRLVRRLGDFCVGVAAFPYGHPRSLDLDTDLARLVAKIRAGADFAISQL
FLEPEGFLRLRDRLAAAGCDVPLLPGIMPLTTIRTLRRGPELSGAPLPPALVQRMERYAD
DPAAFRAEGMDVTAEMCARLLAEGVRGLHFYTLNRSLATVELVQRLGLGARRAAPALTGC
>A0A355FS35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKITQHISEAKDTLFSFELLPPLKGENIHQINQTVEALLEFNPAFVDVTYHREEYVYQEV
QSGLLQKRTVRKRPGTVGICAAISHKYNLDTVPHIICGGFSKEETENALIDLDFVGVENV
LVLRGDPIRSEGRFKGEADGHSYAIDLLNQVADMNQGRYLDVNLKNTNCTQFCIGVAGYP
EKHFEAPNMASDLRWLKRKVEDGAEYIITQMFFDNQAYFNFVKNCRKSGIDIPIFPGLKP
LTTKGQLTSLAQNFHVNLPDELVEQVEKAKSKEDVRAIGLEWCIEQARELKAANVPGLHF
YTMGRAQPTAKIAREIF
>A0A1J7C4E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces gilvigriseus|TrEMBL
MLASGKQSFSFEFFPPKNEKGERTLWKALRRIEQVGPTFVSVTYGAGGSTRGRTVEATER
IATETTLMPAAHLTAVDHTVAELRHLIGQYADAGISNILALRGDPPGDPMGPWTPTPHGL
DYASELVALVKESGKFCVGVAAFTAKHPRSRSVEEDTRHFVAKCRAGADYAITQMFWDVD
EYLRMRDRVAAAGCTVPIIPEIMPLTLASQIERFGQLGDSPMPEDLVARVRRAAEGLGGE
NDAAARAEVRAIGVDHATRMSERLLAEGVPGLHFITLNQSTATLEIYRNLGLDARR
>A0A059KNM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerotilus natans subsp. natans DSM 6575|TrEMBL
MTTTPAAPLPLSLEFFPPKTPEGTAKLAQVRRELYVLEPQFCSVTYGAGGSTQDGTIGAV
QAILDEGREAASHFTCVGATRESVRERLAQFKAMGLKRIVALRGDLPSGFGPMGEFRHAS
DLVSFIRAETGDHFHIEVAAYPEMHPQAKSPQADVQAFAAKARAGADSAITQFFFNSDAY
FRFVEDAQALGADIPVVPGIMPITNSSGILRFADSCGAEVPRWIRLRLQSFGDDSASIRA
FGLDVVTDLCEQLRCAGVPALHFYTMNASATVLEICRRLELIPAAAPAQ
>A0A2E2NZJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MRVIDKLKSTKDTLFSFELLPPLKGKSIDSIYAGIDPLIEFKPAFINVTYHREEFIYKKR
EKGYLEKIAIKKRPGTVGICAAIKNRYNIETVPHLICGGFNKEETENALIDLNFLGIDNV
LALRGDPIKTESHFVPEEGGHRYAVDLVKQVVDLNKGIYMDENIENATPTNFSIGVAGYP
EKHFEAPNMTADIKRLKEKIDAGADYVVTQLFFDNEKFFKFVEDCRKAGIDVPIVPGLKP
IESLRHISFLPKFFNIDLPPALTDELEKCSSNEEVREIGKEWAIAQSKELKAAGVPCIHY
YTMGRSSSVKEIASKVF
>A0A5B8R124|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella decolorationis|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETNLIAAPHLTLVDASDEELLDLAKQYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPSWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPKAV
>A0A0R0MFJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cylindrospermopsis sp. CR12|TrEMBL
MQENHTTIHTSNSLTSFREAVQAGEFLITAEVAPPKGGDISHTIAMSATLKGRVHAVNIT
DGSRAVLGMSPLAVCAILCQHGIEPICQLACRDRNRIGLQADLMGAHALGIRNILALTGD
PVKAGDHPDARAVFDLESVRLLQLITNMNQGLDFNHRTLVDGGLDLFAGAAVDPQSKSWS
GLQSRFERKVQAGAQFFQSQLITDFEKLEKFMDKIASSYNKPVLAGVFLLKSAKNAQFIN
KMVPGVNIPDHIIQRLAKAKYPLEEGMKIASEQVRMAKDLCQGVHIMAVKKEEAIAPILD
LAGVSR
>A0A259H8V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp. 39-42-12|TrEMBL
MFEKFCDVLCLEKNFITVEINPPHGASIDGIIAEIKKYNLHEKVTGFSCTDNPLAKLKMS
GVLSAIKVQQTFGKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKFSDQPD
VKGVLERDSTLLLSIIHHLNKGVDYSNKQLNPAPKPIYPFAVSNATAKDMNSLKKRMVKK
LNYGARAIITQPVYDVDNAKELLALFEEAKEESIRDTAKEAQLVLGQFPIVRAKTANFIN
DKVPGISVPKSIIDEMNLASMDGEEREQEVGFALSKRIFDEMMEIHGKVHLMTHNRFDLC
SELIE
>X8I8D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium sp. OBRC1|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHFTCIGSKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEPGD
FNYAKDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A2K9NZG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monoglobus pectinilyticus|TrEMBL
MKISQLFKNKNDKPIISFEIFPPKKEEAFENVGIMLKELSYLEPKFISVTCGAGGSSNRN
KTIELASKIKNEFNIESMAHMTCISSTPDSVLEEVKAIQDEGIENILALRGDIPKEGFEP
EKASYSHAFELIKEIKTNSELCVAAGAYPEGHIECDDFNKSIEHMKIKEEAGADFFVSQL
FFDNRYFYRFFEAAEKAGITVPITPGIMPMMSKSQISNMIFMCGASLPSEMVRILYKYES
SPDDLLKAGIEYAGRQISDLVKNNTCGIHLYSMNKPEIAKQLLEYV
>A0A0Q8U592|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium sp. Root77|TrEMBL
MSPHETALGPVARAAAGNTRRPSVSFEFSPPKTPEAEVSLWEAIRRLEPLNPSFVSVTYG
AGGSTRDRTHRTVVRMLKETTLKPAAHLTCVEASKAEVDEVVQAYWDAGIRHIVALRGDP
PGNIGGVYAPRADGYLNATELTAGIKAVAPFEVSVSLYPQIHPESPSIDHDIEVLKAKID
AGATRAITQFFYDIDAYLFFMDKLRKAGVTIPVSPGIMPVSNYKGLKKMAGPVGIPLPAW
LGNLFDGLDKDPETRKLIAASVASEMCVRLAEEGYSDFHFYTLNRADLVYAICRVLGVRE
APTEPSEVAA
>A0A2T5IBA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus patagoniensis|TrEMBL
MKIRDMLEKGEPTVSFEIFPPKSSYSLETVFDTLTELKGLHPDFISVTYGAGGTAQSNTV
EIASRIKKDFGIESIAHLTGCTSTKEGMKRTLASIKDSGIENILALRGDIPQEKLADKNW
KPEYRYASELIDDIKAAGDFSIGAACYPEGHVDSINKVDDLKNLKKKMDHGADFMITQLF
YDNDLFYQFKEKLDLVGIEQPVIAGILPVLNIKQVKRIQEISGCNLPPKFLRILERYEHD
PASLQEAGIAYAVDQIIDLLSSGVDGVHIYTMNKPDATRRIMENISCVRKAVCRKEPQR
>F0ET39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parainfluenzae ATCC 33392|TrEMBL
MSYANEINTLNQHLADTNKKINVSFEFFPPKNEKMESMLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGIEAAPHLTGIDATPEELKEIAKDYWGSGIRRIVALRGDEP
KGYAKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIEAEIVPGILPVTNFKQLQKMASFTNVKIPAWLAKAYEGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHTLGIRPTTNP
>A0A4P6UG99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. ABRD24|TrEMBL
MTRTPSIVDRIRSSTSGRIPFSVEFSPPRDADAEARLWRAVREFERLGPAFVSMTYGAGG
STRDRTVRVTGQLAEDTTLLPVAHLTAVGHSIDELRSMCGAYADRGISNILVLRGDPPGD
PLGEWVKHPDGVEYAEELVRLVRDMGDFHVGVASFPEGHYRAPDLEHDTKYLVSKLRAGA
EYSITQMFFDVEDYLRLRDRVSAFDREQGDKPIIPEIMPITSLRSARRSLELSGSTLPPA
LEERLTRAAGTGAEENRAAVREIGIEIATEMSERLISEGAPCLHFITLNFARATSEVLAN
LGMAAPAAV
>A0A0W8G643|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrocarbon metagenome|TrEMBL
MKILDLLRDNKPFVSLEFFPPKEKSAWPGFFDVVGWLKPANPLFVSVTYGAGGGTQANTL
EIVSRMKKDYGLEPMAHLTCVGASEKNIRAFLDSLVDSGVENVLALRGDPPRGQADFVPD
SDQFRHASDLVAFIRAEYPALCIGVAAYPEVHPQAESPEKDLEYLELKIRMGGDFAVTQL
FFDNRLYFDFVARAASRGIHVPMLPGVLPVNSLAGVKRMLTFCGASIPPDYLRSLEEADA
AGGNEAVAELGIAYATRQSRELLAGGAPGVHLYTLNKAEACLKIIGGLGLSS
>A0A847HBZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium marinum|TrEMBL
MNATAPHHSVKRRFSASVPLDSFDPVETHQAPVPSRTSLSFEVMPPRHDVDETKIDELLA
TLGSYRPDYISVTSSRNSGWLEGTARFIEKVDAQTRIPTLAHLACTAGTRQELIDWINRL
MDSGVRGFLALRGDYAEGQTGMPAGYLPHATDLISLIRSLENDQRARFGAGRLAIGVAAY
PSGHEESASRDEDIDVLLAKQRLGADFAITQLFFDAEDYLRFAERARLAGVRIPLIPGIM
PMTSLARLRRMGELSGLTVPDRLTRRLAAAGPEGEYQTGLDLTAELAQTILAAGAGGMHV
YTFNRPDTTTELLDRIGIAPRPTG
>K1S5Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|human gut metagenome|TrEMBL
MSVAEIYEKRATFSFEVFPPKTDVGMEKLCGKDGVLEKLYTLNPDYISCTYGAGGTNVGK
NLEVLDKIVKDGKTTPVTHFTCIGNTKEDIKEKLQTYLDHGIDHMLALRGDLPFGWAGTN
GDLHY
>A0A1H0CRR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allokutzneria albata|TrEMBL
MTAVVDRLRSDRPVFSVEFFPPKDAEAERQLWRAIRELEPLDPAFVSVTYGAGGSSRDRT
IRVTGRIAQETTLTPVAHLTAVNHSVAELRNVIGSYASVGVRNILALRGDPPGDPNGEWV
KHPQGLTYAEELVRLIRGLGDFCVGVAAYPFGHPRSADLDTDAEFFVRKLRAGAHYAVSQ
MFFRVEDFLRLRDRIAARGIDLDEVPLLPGLMPIRSVKGIQKMAEMANTEIPPEVIARVE
PYAGNLESVRAVGVDIATELAERLLAEGLKQLHFYTMNRSNSTVQVLDRLGLLPARARG
>A0A8D9ZNE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus A017934/97|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A845MQ75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp. DP30|TrEMBL
MKRISFEFFPPKTDEGKSKLLATQKKLLVKNPEFFSCTFGAGGSTRDNTRDMVNKLREQH
GDTAPHLSCIGQSKDEILELVNGYKEAGVTRIVALRGDLPSGMGYAQSEIKYADELVTLI
REETGDHFQLEVAAYPEMHPQARSFEDDIAHFKRKVDAGANSGLTQYFYNADAYGYYMDA
LDKIGCDAPVYPGIMPILNVANLLRFSNTCGADVPRWLQSKLNDIKDDDAAVKAFGEEVV
TRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGL
>A0A1C0A4D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHAVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPTVTPKDDF
RYASELVSFIKENGDFNVIGACYPEGHLEASTLKQDLIHLKEKVSAGTDQLISQLFFDND
YFYTFLDKARDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEYHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKSV
>A0A1B9KGA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNQLFNKKTVFSFEVFPPKRTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHAVKYTYGIESVAHLPGINFSKVEMQKILADLKCAGIDNVLALRGDISPNVEPKNDF
RFASELVTFIKENGDFNIIGACYPEGHLEAPTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFFAFLDKAHDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQIMEKYEHHPDAF
RDAGIAYAIDQIVDLISQNVDGIHLYTMNNSYIARRINEAVSTLLEIPKAQ
>A0A1G9N3V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dendrosporobacter quercicolus|TrEMBL
MKIAIELVPRDEASLLAELEVVKSDFPDIDTINIPDLLRYDLRSWEGCVYAQDRYKSAIP
HIRAIDIDLDKPLPMGDFLQKHHIREVLVITGDLPQDMKWKIYPSTSIEVIRKFKEELPG
IKVYAGIDQYRDSMRKETDYIRRKIQAGADGFFTQPFFDLRLMEIYAEILAGQEVYWGIS
PVTSEKSLSYWETKNNVVFPACFKPNLSWNIMFARQALQFTRQSDTNIYFMPIRTDVKSY
LQGIFGGAQAGS
>A0A556S9R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNQKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKTEMKKILHDLKCAGIDNVLALRGDINPNIKPKDDF
RFASELVSFIKENGDFNVIGACYPEGHLEAATIKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKARDMGIDVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKSI
>A0A4U8S5E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. MIT 05-5293|TrEMBL
MFGIEFLPQSLDKDINQLDAMIKGAKQYLNQEVDFVLIPANPRKCASVDSLLAASLLRQK
IKDYVFVPTLSGSGCESQSGKMRLSSQLLAVKYANFQTLALIGGENEGMSSVEMMIIARE
ILGEKVRIISGSGALDDAKNRHRLEQKLQAGVDMIITQPLFCAKEARTFLQIFESLKQQG
GYKAQAFIGVFGVFNVHTALRINEAHLGFEIPQDYIESMDSVCGENTEERMEHRPKQRYE
QLWQEMEKVAQEYGAFLYLSTPKHNDLRAYGICEG
>A0A353D7T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp|TrEMBL
MQIAQLIAASRSPFLSLEFFPPKDRGTWPGFFEEVGKLKALNPLFVSVTYGAGGGTQANT
LDVVTRLKRDLGLEPMAHLTCVGASASALHGFLKELVAAEIHNVLALRGDPPKDRPDFRF
EGQEFQHASDLVAFIRREYPGLGVGVAGIPTKHPESATLEDDLRWLKFKVDAGGDFVVTQ
LFYNNAHYFEYVRRLRGLGLTVPVLPGILPIMSMKSAQFISGLNGRAVFGGFYEVLEQAF
ARGGDEAVRELGLAHATRQAQDLIDRGVPGVHLYTLNRAEACLEIAGNLKL
>A0A1B9M3L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVQPKDDF
RYASELVTFIKENGDFNVIGACYPEGHLEAATLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYTFLDKARDIGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPEAF
RDAGIAYAIDQIVDLVSQDVDGIHLYTMNNSYIARRISEAVSTLLAVPKSE
>A0A5S4U9C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya sp. ws52|TrEMBL
MSFFHANHQEALNQNLAELQGRINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPPGAGKPEMYASDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRSELSYAICHTLGVRPATLA
>A4G973|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herminiimonas arsenicoxydans|TrEMBL
MTQQNFSIEFFPPKTPLGVEKLRVTCAKLAELNPKYFSVTFGAGGSTQHGTLDTVLEIRS
AGHDAAPHLSCLGSSRENLRAILQEYKSHGIKRIVALRGDLPSGYGAMDASSSEFHYANE
LVEFIRAETGDWFHIEVAAYPEMHPQAKSPSDDIASYVRKVKAGADSAITQYFYNADAYF
RFVDDARKAGADVPVTAGVMPITNYSQLMRFSDMCGAEIPRWIRLKLASYNDDTDSIRAF
GLDVVTDLCERLLAGGAPGLHFYTLNQAAATHAIWSRLNLSQK
>A0A0P1HZ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leisingera aquaemixtae|TrEMBL
MTTPKISFEFFPPKNLEASFRLWDTVQVLAPMDPRFVSVTYGAGGTTRTLTRDAVATLHN
SSGLNVAAHLTCVNASKAETLEIADQFAEAGVTEIVALRGDPPKGEGKFTPHPEGFADSV
ELIKGLAARGGFTIRVGAYPDCHPEAASQAANVEWLKRKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDGSRLTPGILPIENWKGARNFAKRCGTVIPDWVENAFDKALRDGREELLA
TALCTELCSDLLEGGVDKLHFYTLNRPELTRDVCFALGVTPKVALENVA
>A0A7C4IWZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MNDLKSGSNLEKVLKAGHFALTGECGPPKGANVEHLKEKFSHLKGVVDAVNVTDNQTAVV
RMSSWAACALMIQNGVEPNFQMVCRDRNRLAIQSDIIGAYALGVRNMLCLSGDHQTFGNH
PQAKNVYDIDSMQLISLVKKMRDEGKFLNEEDIDIPPKMFIGAASNPFADPFEFRVYRLA
MKIAAGADFIQTQCIYNMEKFRTFMKMAVDMGLHEKAYILAGITPMKSVGMAQYMAKSVP
GMDVPETLIQRLKGAGKGKAAEEGIRFAVEQIQEFKEMKGIAGIHLMAIEWEHMVPEIAE
RAGLLPRPKIS
>A0A1Q3FKE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Culex tarsalis|TrEMBL
VRFVGGHLSFFAQNLSADVLVXCLSSSSRDLLQTARGTTRVTIEKRTESVRLRGLNLSSP
SREKRRPPPSAAPMHRQTVESDPNGEEDKSTILAAATADAMHSHENSRNLKQVVQRWTTS
ERLRYSIELIPREDFQLDLGRLAPVFCSLPWISDNNLQYSRFVDTPMLKMTAKIVPHCSV
MNHLSCYNITETQVDKFVDMGNWNLFVIRGDTVSEGQRFQHSCDLVEYLRSKNNPDLTIG
VGGYPYGHPESPSVDHDVKFLKQKVDLGVDFIVTQTLYDAASYLTYVDECRRAGIAVPIV
PGLFLPGSAEQLETVLALTRVNPPADVRELLQAHAHDEPEAFEAFVVKHFAELIRTLRRE
RPDEVKLVHFFTFNRLDLLKKVLDKIADLL
>A0A7V5F0A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
DIDSIQLIALVKKMRDEGKFMNDKDIDVPPKLFIGAASNPFADPYEFRVYRLANKIEAGA
DFIQTQCIYNMDKFRDFMKKAVDMGLHEKAYILAGVTPMKSVGMARYMSKSVPGMDVPDE
IINRLKGAGKGKVAEEGIKFALEQIEEFKEMEGVAGVHLMAIEWEHKVPEIAERAGVLPR
PVV
>A0A4W5NBV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hucho hucho|TrEMBL
MVNNVQRVDDTWRTCTKSDSSGTSSGGESSKESSRSSTPVLDADRMDRLRDKMRRRTESG
DHWFSLEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKDKITGYLSKAKRLGLKNIMALRGDPVGADWEEEEGGFNYAT
DLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADTF
LKFVRDCRAIGITCPILPGIFPIQGYQSLKQLVKLSKLEVPEEIMRVIEPIKDNDAAIRN
YGIEQTVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLKMWGEELTSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLLMDELDKVNR
RGVLTINSQPTINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENITVLLKVLKKYEPRV
NYHIVNVHVSSTTYISLHVHLFCELKRIVRFLYWSIVFIYRVRIRRTPMTCNPTL
>A0A6I7WZJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium CS3|TrEMBL
MTIKNKADLFSFEFYPPKTEQGDLNLEQVHRDLAKLNPDFFSVTFGAGGSTRDKTYDTVV
KIQKNGVSAAPHLSCVASTKENIREILANYREHGVSKIVALRGDLPSGMMSAGEFRFANE
LVDFIRAETGDHFQIHVAGYPEVHPQAGNATEDFNNFKRKVDAGADAVITQYFYNAEAYF
YFLDKCEKSGINIPIVPGIMPITNYAQLFRFSDMCGADIPRWMRKTLECFGDDKASIMAF
GEDVVSKLCQELLDNGAPGLHFYTMNQSKPTLAVWDNLSFA
>A0A1F7QMG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium RIFCSPLOWO2_12_FULL_73_47|TrEMBL
MATRRDTPFREAMRSLLVFDGAMGSLLYERGVFVTQNFEQLNVTRPDIVLKIHDDYVAAG
AQVIETNTFGANRFRLDRHGLADQVRAFNVAGARLARQAAGETVWVGGSMGPSGLVPGVA
TQPELALVSATFAEQAAALVAGGADVLVLETFRHLAEIRLALEAAREAAPDTPVIASMTF
DPTGTVADGSTPEQVASTLRDLGADAIGVNCGDGPQLALAIAERLVRSGLPLCVQPNAGL
PRNVDGRLLYMATPEYFDVFLRRTVQLGATMIGGCCGTTPEHVRWMAKSARMLGDRRVEV
APAGAVATAEAFAGLAPTPLAERSAFAAKVAAGKFVVSVEVNPAPGVDPSKALEGAKMLI
DSGVDIVNVADGPRAMARMSNLAFCALLLVRHGIQPILHVCGRDRNLLAQIAHLLGAHAI
GIRNLVIITGDPPKVGDYPEATAVYDLDSIGLLHVASSANRGVDPAGKPLPGGKTAFLLA
TGFEPGAADLEREIQRLEKKKTAGAELVMTQPIFQQDLLDTVLRRIAHLELPVMVGVLPL
VSYKNAEFLHNEVPGMQIPEEIRERMRRTPGGEAARKEGVRIAREMLFAVRDRVQGAYLM
PPLGRYELALEVLEGLRV
>A0A291P687|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas beimenensis|TrEMBL
MNMNVGADRGHLASDTPGYSSAGRLERVLRAGHFAVTAELAPPDAANPEEVYARARVFDG
YVDGLNATDGSGANCHMSSVAMCALLSRMGYETVMQVSCRDRNRIAIQGDVLGGAALGIN
NILCLTGDGVQVGDHPEAKPVFDLDSMSLLETVARLRDKHVFASGRKLSDPPRVFLGAAE
NPFVPPFDFRPHRLAKKIAAGAQFIQTQYCFDLPRFRTFMARSRDLGLLDKCFILPGVGP
LASARTANWMRRNVPGIHIPDAIISRLEGARDQKAEGRNICIEMIQQLREIEGVSGVHVM
AHRQESSVADIIERSGVLGDRAPWTPSRESALEREYA
>C5WVY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorghum bicolor|TrEMBL
MKVIEKIQEAAGNGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPSEITAALDPIKDNEEAVKQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIGILMNL
GLIEESKVSRPLPWRPATNVFRVKEDVRPIFWANRPKSYLKRTLGWDQYPHGRWGDSRNP
SYGALTDHQFTRPRGRGKKLQEEWAVPLKSVEDISERFTNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLD
QLIEKIKAFPSLTYIAVNKDGESFSNIAPNAVNAVTWGVFPGKEIIQPTVVDPASFMVWK
DEAFEIWTRGWACLFPEGDSSRELLEKVQKSYYLVSLVDNDYVQGDLFAAFKI
>A0A368JPV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Larkinella punicea|TrEMBL
MAKVSDHIRQANGKTIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
VEPDGTVKKIITRKRPGTVGICSAIMHKFGVDPVPHVLCGGFTKEETEDFLIDLHYLGID
NVLVLRGDPAKPFDTFKPKTNGYAYASELVTQVANMNRGVYLHEGSHAMTPSNFCIGVAA
YPEKHFEAIDHDTDFRYLKLKIDKGADYIVTQMFFDNQKYFDFVRRCREAGITVPIIPGL
KPLSTRKQLQVLPRLFHLEMPADFVKAVEACEDDKQARQVGIDWCIQQCRELTKAGVPGL
HFYTMGKSDNIVKIAREIF
>A0A1Q5TNU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus eapokensis|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLDAAPHLTCIDASRGELSNIAHDYWQNGIRHIVALRGD
LPANGCKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFSSMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A4R9WQI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.217.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARYEVDAVIQEFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A1K1SBF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. NFACC33-1|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTDLCRRLIDAGVPGLHFYTLNAATATRTICERLAV
>A0A0M8VRP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MMG1121|TrEMBL
MALGTASTRTDRARTVRDMLATGKKTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFEPESYLRLRDRVVAAGCDTPVIPEVLPVTSVKMLERLPKLSNAVF
PDALKERILTAKDDPTAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A1Y3T4P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. An81|TrEMBL
MKITELFERGEFVVSAEVGPPKGFHVEHLLEEAKTYLSGITAVNVTDNQSSVMRLGSLAM
CKALKDEGLTPIYQLTCRDRNRIALQSDLLSAAMFGIENLLLLTGDHTKLGDHPQAKPVF
DLDSVSLIHAVKKLEEGVDLGGNELIGEAPKFAKGAVVSPCSDSVDAQLAKMERKVMAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKKDKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKVPELLKAAGI
>A0A2Z5YUM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altererythrobacter sp. B11|TrEMBL
MSYAAIHPDWEKPRSNMVDGYSLEMTAKEIEGLREAAPLIRPGTQIAVTFLPGEEMEQRV
EAAVLVRQLGFEPIVHLSARRLTSEAELDKYLADITGKAGVKRVFIIAGDPPEPEGPYST
SLEIIETGLLEKYGIQIVGVGGHPEGHPNNSKDELWDWMERKLAAVRAHGMTPLIVTQFA
FDDDAIVEWVGEMRSRGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGISLTN
LIGSAGPDKLVDSLDKKLSDAEHGRVRLHFYPFGALTASAEWINKYDAKHS
>A0A5T1V1F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITKKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A8G2IUI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae|TrEMBL
MALKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTRAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESHDAAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRPGRETKSAGA
AA
>A0A7M2XTM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus pyridinivorans|TrEMBL
MSRTPSIVDRLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERLGPAFVSMTYGAGG
STRDRTVRVTGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGN
PLGEWEKHPEGLEYADELVRLVRELGDFHVGVASFPEGHHRSPDLDHDTRYLVQKLRAGA
EYSITQMFFDVEHYLRLRDRVVACDAEQGLKPIIPEIMPITSLRSARRSLELSGSHLPPV
LEERLRRAAGDGPEENRAAVREVGIEVATEMCERLISEGAPCLHFITLNFARATGEVLDR
LGYELEAPAAVQPA
>A0A7X0HSZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus benzoevorans|TrEMBL
MNFLERMKNEILIADGAMGTLLYSYGKDTCNEQLNLSHPEQILHIHKAYLAAGADVIQTN
TYAANYLKLSRYGLEDSVKEINSAAVKLAKQAAKVSGYVLGSMGGNRGIKPQSISLEEIK
RSFREQLYCLLLENVDGLLLETYYDLEELETVLTIARKETNLPIIAQVSIQETGFLQDRT
PVAEALNRLEGIGADIVGLNCRLGPHHMLMALEQIPIPKKAFLSAYPNAGLPAYIDGVIQ
YESEAEYFRKSAQAFREQGVRLLGGCCGTTPEHIRAFASELKGAVPVQEKTIAIKEKKII
IEAKKIEREYPPLQELVKKRPSVIVELDAPKKLDTTKFFAGVNALKTSGIDALTIADNSL
ASPRICNSALGYLAKTQYNMRPLIHLTCRDRNIIGLQSHLLGLHTLGLNDLLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKMLNEGQSYSGKELGQKTAFSVAAAFNPNVRQIDKAVN
RLEKKISCGADYFITQPVYSEEKIRSVYEETKHLDTPIYIGLMPLTSSKNAEFLHNEVPG
IKIDDSIRESLAALKDNPLKAAQEGIRITKSLIDTAAELFNGIYLITPFMRFEMSVELSE
YAHKKTAERVRRNHRVESINQRTNQ
>A0A6I8UDT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila pseudoobscura pseudoobscura|TrEMBL
MFAKFLPTKTYLCFNASSDSYFKTILLVLRSAPGWRCSSASRKASVRRLDCGLPQRSDDR
RAITHTNVKLIRTSAKSIRETVTAADRYSRYQAQFRAICQRVSIFESDCEMHATETVPSI
GLAPISYVPCVHYATHQNGTDHRELRVADLVAERTARRQFFYGIEMVASQEGKPTCLDFN
EFLPVLPTFLSIVWLGATYCSVDPIELVTSLQLARSLEARIPVMPHLSLYCLTEERLNEF
LALNFTNVLPIRGDAVKEGQTFRYTQQVVEHIRRQRGDRISICVAGYPEGYTNLAEPQDP
AEAMRYLKAKIAAGADCIITQMCYRSDTIIQFIKDVRSAGITVPIVVGQLVADSFRTYCL
SENIAGVHLPPGLRSELLAIESDAERVSQFFIQLSIRIIRDILAADVGVYGVQFYTFNQF
APVQAVLKELRTLDILKDEGGQ
>A0A150K4W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weizmannia coagulans|TrEMBL
MDFLETLKNRILVADGAMGTLLYAYGANTCYESFNLSHPEDIHAIHRAYIEAGASVIQTN
TYSANYIKLAQYGLEEKVKDINKAAVRIAKEAANRDTFILGTVGGIRGQRKTEATLAEIK
RTFREQIFHLLNEGVDALLLETYFDAEELYTVVDIAKKEADVPVIAQFSLIEPGVLQNGT
PVRDAFKELENRGADVTGLNCRLGPHHMIQAFEEIPIPKRAFLSAYPNASLLDYEEGRFT
FTNNADYFKTCAEKLVEQGVRLIGGCCGTTPAHIKAIAEGVQGLVPVTEKTVRPPKIEIA
AAPAQYEPPLHEIVKKRHSVIVELDTPKTLNTARFFEGAKALHDAGIDALTMADNSLASP
RISNTAIAAILKEKHGIRPLVHITCRDRNLIGLQSHLMGLAALGIDQVLAVTGDPSKIGD
FPGATSVYDLSSMELIAMIKQFNDGISHSGKSLHRKTNFSVAAAFNPNVRNLDKTVGRLE
RKIRHGADYFITQPVFSTEKIEQIHEATKHLDAPIYLGIMPLTSYRNAVFLHNEVPGITL
TDDILQAMEKTNGDPVKAREESLAISRTLIDAALAYFNGIYLITPLERYELTVECTRYIH
EKTAVRSAGIF
>A0A4P5X893|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MRGRVYISPSLMYLPDHFQSRKRTVSFEFFPPKTPQAAGELFDAIRQLESLRPSFVSVTY
GAGGSTRDVTHDLVVRLKTTTALDPIPHLTCVCHNESDIQRILERYAAAGISNILALRGD
VPRDLPAGTPAWIDFRYAANLVAAIRKFNDLKRHPHPKGFGIAVAGYPEGHAETPNRMVE
LDHLKAKVEAGADFIITQLFFDNRDFYDFRARCELIGVRVPIIAGIMPITSVQGMKRMAE
LSLGSRFPAPLLRAMARAGNDPEAVRRVGVHWATEQCRDLMDHGVAGLHLYTLNRSTATQ
EIYNSLGVKDSEGLAY
>A0A1H4U9I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces misionensis|TrEMBL
MREILAGGKKTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVKE
TQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGQWVPHP
RGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDTDVAHFVDKCRAGADYAITQMFF
RPESYLRLRDRVADAGCDTPVIPEVLPVTSVKMLERLPKLSNADVPDALKERILAAKDDP
AAVRSIGIDFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>A0A5N5RJJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium jacchi|TrEMBL
MHTPMFSLEVFPPKRNAPVGTIYDTLDGIEDLGPDFISVTYGHGTHSDRTATARIANTIV
NEYGIPAVAHLTALYSSRKQIDEALDMFEQAGVTAVLALRGDYLDGETPVGEFTYASDLV
AYIRSRRPDLKVFAACYPEGHYQAGSLDEDIEHLKIKIDAGATHLITQLFYDNDDFYRFR
DKASAAGINVPIEAGIMPVRGAKSTRRMAERNASRIPEHLNVLLERWQDDIQSLRTAGIL
YACEQIADLVAHGVDGVHLYTMNHPATTRRIWRNVETLLGTDSAGSSAGAADAAADATAA
E
>R8B389|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter lipolyticus SM19|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEENPDFFSVTFGAGGSTRDRTIETV
LSLHKQGISTAPHLSCVGGTRKDIAELLDLYKENGINRIVALRGDMPSGMGAAGELRYAN
ELVAFIREHSGDHFNLEVAAYPEFHPQARSAEEDLKNFARKVDAGANSAITQYFFNADSY
FYFIDRLEKMGITIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCEKLLRAGAPGLHFYTLNQAQPSIRIWENLGIGEREKIAF
>A0A4R0BKA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae|TrEMBL
MAMSQAIHLRDQSDVLDDFSVEVTTKDTAQLAAMSGAIPKGTIISIPFLSTESDADRIRA
AKMVRQAGYVPLPHIAARRLGSESILSAMLSALVNDAQVSRLLLVAGDADPPKGPFLDTA
TILRSGILEQHGISNVSIAGHPEGHPVQNAAMLTSALLEKRLIMEAANIEWSIFTQFAFA
SEPVLAWIGELRRLGIEVPIHIGIPGPASVRTLLKFAAVCGVSASTSVLKKYGLSITQLL
SSAGPDALVNEYATGLSNAEYGDVRLHFYPFGGLHKTVDWLQEYRTRPS
>G2QSW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermothielavioides terrestris (strain ATCC 38088 / NRRL 8126)|TrEMBL
MGEFLPSLELPPEAVKNHGMEKITDKIAALPAGTDYFSLEFFPPKTAMGFSNLRGRLDRM
ARALRPLFVNVTWGAGGSTAIKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALDDAK
ALGIRNILALRGDPPRRAEYRDFNEPEPTDEEEEFAWAVDLVRYIRKTHGDYFCIGVAAY
PEGHADGSHPLGQSLEHDLPYLVEKTQAGADFIMTQLFFDIKAYKHFEKTLREHPSGAFK
DIPIIPGLMPIQSYQMIRRTTKLSHAKIPDALLARLDAVKNDDEKVKEVGVDIISEIVEQ
IREIKSRTDAPRGFHFYTLNLEKAVSFIVERTGLISPTTPEPEQAIDDQQNPLPDIGLLR
VNGSDQSSQEPPRRRQPSIGSDPRDRVIVPGRSASYPDWEATALEASVPAGPINSRANTL
AISEGEGVLGREATWDDFPNGRWGDARSPAYGQIDGYGVSLHVTVAQARELWGTPRTPQD
VSAIFIRHLRGELSTIPWSEESFSAETDQIRDRLVALNSKGWWTLASQPAVNGLPSSDPT
FGWGPENGFVFQKAFVEFFLPSEDWKALEQKLTRPEMKDVVCFYATNAAGDYVSSDTAFP
RAPAAARGGAAAGEQQEASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWGEWAK
IYAKGSDSSRFLESLRADLWLVNIIHHDFVDSEALWELLLD
>A0A2D6YT16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MDALDSATAPTVSFEFFPPSTPAGWMNLDRRIAELVPLEPSFVSVTYGAGGSTRELTNDL
VVRLLEETKIPAVPHLTCIGHTHDEIDGILERYAEAGVTAILALRGDPPRDGSDPDAGHF
DHASDLVEHIRSFGDRHRYRFRIGVAGFPEGHPDTPNTLEGMNHLKMKVDAGADWICTQL
FFDNHAFLDWRDRCRIERIDIPIIAGIMPISTRRSVTRMAGLAAGTVFPASLQRSLARAG
RDDEDAVSEIGLHWATEQCRNLLDHDVDGIHFYTLNKSDATLRIHRSLGVRSARGLQRRG
P
>A0A2D9C5V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MSHFRELFESTTFSFEFFPPKTEAGAQKLFDHIVKLEKLRPSFVSVTYGAGGSTRQLTRD
LVHRVRAETGINTVPHLTCVKHSESDIRGIVEGYAQRGIQSILALRGDPPHNEPHCFGDD
RFSNAGELVRFIRKIEDEQRQLNGFKGFGIGVAGFPEGHPSTPNRITEMEYLKAKIDAGA
DYIITQMFFDNRDLYDFRDRCEMAGIRVPIIAGVMPIQSISGMKRMSELALGMRFPAPLL
RMVRRTDGSDEAIRRVGVHWATEQSRDLLDHRVSGIHFYTLNSSGATMEIYKTLGVQDSQ
QLGSEPTLPF
>E3J0A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia inefficax (strain DSM 45817 / CECT 9037 / EuI1c)|TrEMBL
MTAVGSAPATPQRAGTRSVKDFLAAGEISYSFEFFPPKTADGERALWQALREIEALHPAF
VSVTYGAGGSTRDGTIRVTERIAAETTLTPIGHLTAVNHSVAELRQVIGSYAGVGVHNVM
ALRGDPPGNPQGEWVAHPEGLRYSSELVELVKSLGDFCVGVAAFPDKHPRSPDLDSDADF
LVRKFDAGADYAITQFFFGPDDYFRLVDRVRARGCSAPIIPGIMPVTNVAQIERMALLSG
ADLPADLVTRLRAVADDPKAVREIGVEVATDLSEQLLAGGAPGLHFITLNRSSATREICQ
AVRARRAGPAA
>A0A1F9NWS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula sp. RIFOXYA12_FULL_46_16|TrEMBL
MKAFSRLHETLKRCEFAVTGECGPPRGANKEVIDKKIKLLNGFVDAVNVTDNQTAIVRMS
SIAASAHLVAAGLEPVMQMVVRDRNRIAILSDIMGAYSLGIRNIPCLTGDHQKFGSQPDA
MNVFDIDSMNLLRTVRNMRDTGKDMSGFDLDTAPQMFIGAAANPFADPFEYRVIRLAKKI
DAGADFIQTQCIYNMDRFKEWIRLSREEGLTEKVYILGWVTPLRSAGMARYMKNKVAGMD
IPDTIISRMDGVDKKDQAEEGIKICLETIQELRELKGVSWVHIMAIEWEEAVGKIVRQAG
LK
>A0A7U8WMG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cholerae MAK 757|TrEMBL
MTLGHREYKMGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKTLQ
PKFVSVTYGANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQ
NIVALRGDIPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRK
VDAGANRAITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVP
NWMVKQFEGLEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGV
RPQA
>A0A4U0SLX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces oryziradicis|TrEMBL
MALGTPSTRTDRAVTIRELLASGTRSFSFEFSAPKTEKGERTLWNAIRRIEAVGPTFVSV
TYGAGGTSREGTVRATDRIVSDTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGDWVRHPQGVEYAADLVRLIKESGDFCVGVAAFTEMHPRSVDWDTDTRHFVD
KCRAGADFAITQMFFDADDYLRLRDRVAAARCTTPIIPEIMPVTNVRQIERFAQLGNAPF
PPELADRILAVKEDPAAVRAIGVEFATEMCRRLLAEDIPGLHFITLNHSTASLEIYENLG
LHQRS
>A0A243AW00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar pingluonsis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIGAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIHISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7C2F261|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobium narugense|TrEMBL
MNELRIKERYKSERTGFSLEFFPPKERDQEEKFKETIKKYIELNPLFVSITYGAGGTTQD
KTFEIVKFVNSFKAFAVLPHLTCIGATKDSVNFLIKKYDDLGVCNILALRGDPPKNVENF
DISKGEFKHAIDLIKYVREYFNHFSIGVAFYPEGHAQASSFEEDFEHCIEKMRLADFAIS
QMFFENSYFLRYRDLVAKRGVDITLVPGIIPIGNFEKIKEFSKFCKVEIPKKLEDIMSKA
SSQLDMKKAGIDYATQQCAELIKEGVKFFHFYTLNQFDLCSKVIENFW
>A0A8C3AGJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclopterus lumpus|TrEMBL
MVNQVQRGDGSLRSCKSDSSGLSNSGGESSKESSRCSTPVLEADRSDRLRDKMRRRTESG
DRWFSLEFFPPRTASGAVNLISRFDRMSAGGPLFIDITWHPAGDPGSDKETSSMMIASTA
INYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEEGFNYAT
DLVKHIRSEFEDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITRVIEPIKDNDAAIRN
YGVQQAVEMCRVLLDSGKVPGLHFYTLNREVAIMEVLRQLGLWIEDPRRSLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSTKDA
LLQMWGAELMNEESVYEVFTCYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNK
RGVLTINSQPNINGKPSADPIAGWGPAGGYVFQKAYLEFFTSSENVTALLEVLKKYEPRV
NYHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWQVIDDMTDLTDEQPMRQKQNF
>A0A3E2JRT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. V59.32b|TrEMBL
MNFREELKSRILIGDGAMGTLLYSNGIGHCYEELNISDPGRIETIHAAYLDAGADILQSN
TYGANYYKLKRYGLEDEVSNINRKGISLARKAAKDKAFVFGTIGASRSIRKSDLSLEEIK
RGFREQLYSQLVESPDGLLFETYYDLEELETVLQIARNETDLPIIANVSMHEIGYLQNGI
HLNEAFQRLEQLGADVVGINCRLGPHHMIRSLEEVQLPKQAYISVYPNASLPDYVDGRLV
YEAVPDYFGSSALKLREQGARIIGGCCGTTPKHIESVKQAIGNLKPITEKEIKARRIEII
ANDHHEKTTALYEKARKERTILVELDPPKKLGVEAFMAGAKALHKAGVDSITLADNSLAT
PRISNVAIGTMLKNQIGTDPLIHITCRDRNLIGLQSHLMGLQTLGLNEILVVTGDPSKIG
DFPGATSVYDLSSFDLISLVKQFNEGLSFSGQSLGQRSNFKIAAAFNPNVRYLHKAVERM
EKKIACGAQSFLTQPVYSISQIEEVHAATKHLETPVFIGIMPLTSSRNAEFIHNEVPGIK
LPDDVRNAMATAGSDPARARAEGVAIARELVDAALDRFKGIYLITPFLRYEMTAELSRYI
RKVDSERFVEVTIHE
>A0A351XBH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKISDILKNNKVTVSFEVFPPKQWDKIENTKSVVREMSKSNPAFMSVTYGAAGTTSGFTT
EIATEIKSSGVTPLSHLTCLTSTKDKIHEVVNELQQNGIKNILALRGDIPKDFEMPDERY
FSYAYQLINEIKSINPDICIGAACYPEIHPESKNRIEDIAHLKDKVDCGAEFLTSQMFFD
NEKFLNFVEMCRIKGIEVPIIAGIMPITNANQIKRSIELSNSSVPEKFFKIMERFGDDPD
KMKQAGIVYATEQIIDLMANGINNIHIYTMNKPEVAESIMKGLSNIINE
>A0A516WC90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium SJ-26|TrEMBL
MTKPDLSLEFFPPRDLAAQERLVRTAKQLLAVHPRYVSVTFGAGGSTREGTARTVGTFRN
FGCDAAPHLSCVGSSRDDLRQILQSYREQGVRRVVALRGDLPSGMGPEAGELRYAAELVA
FIREETGDAFHIEVAAYPEMHPQAAGPGEDLAHFAAKVRAGADGAITQYFFNADAYFDFV
ERARTAGVDVPIIPGIMPITNNSQLSRFSAMCGAEIPRWIKLRLNEYGDDRASIKAFGTE
VITDMCRRLLDAGVPGLHFYTLNQADPVLDIWRGLGLDS
>A0A1Y2GBH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lobosporangium transversale|TrEMBL
MKIIDKITRAEEERRPFWSFEYFPPKTTAGIQNLFDRMERMYNLGPEFVDITWNAGGTSS
DLTTELVATAQSVYGLETCMHLTCTNMPKEKIDAALKAAKACGNQNILALRGDPPRGQEQ
WVSCDNGFSYASDLVAYIRQEYGDYFSIGVAGYPEGHLDSSSKEDDFKWLKHKVDQGADF
IVTQLFYDTELFINWVKECREYGITVPILPGIMPIQNFGGFTRMTTLCKTYVPERIKRAL
EPIKEDDQAVKDFGVKLAVEMCKEIQAAGINGFHFYTLNLEKSTRLILEGLEFVAPRENI
RQLPWNPSLSKKREKENVRPIFWKNRIKSYVARTEAWDEFPNGRWGDSRSPAFGELDGYG
TSLKVTAKEALELWGYPESPKDVAILFSKYCRGQVKSIPWSDESSLYPETEAIRDRLAEI
NARGYLTINSQPAVNGVRSDDKIHGWGPKNGYVYQKAYLEFFVSPENLSELVNKIEDEPQ
ITYYAVNKRGDLRTNSQTDGPNAVTWGVFVGKEIVQPTVVEVVSFMAWKDEAFELWSEWS
KIYEASSMSTKVINAIRDEWYLINIVHNDFQDPEGLFRLLDSVKTVDHSAFVANGRS
>A0A4T0CXL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MDRVHLFIFFILFFIAKRLISRHRQVNRRAAAKEKKATYSFEFFPPKTAQGVQNLYDRMD
RMHNFGPSFIDITWGAGGRHASLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEA
HDAGCTNILALRGDPPREKEKWEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDD
NDNPEELIQHLKEKVDLGGTFIVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHA
AFLRRANWSNIHVPPHWHEALEPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMN
LAQSTRMILEELSITPSQDTPLEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDW
DEFPNGRWGDSRSPAYGELDTYGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVES
LPWSESPITDEADALRKDLINLNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAY
LEVLVSPELISELITRMERNPNITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPT
IVETVSFLAWRDEFYRLGSDWSRCYDAISPSRYVIDDLMQNWYLVNIVNNDFREQRGIFP
LFDELEVPDLNKEVTAPEAPQKVNGATNGEKHQEEPKVGNGDVTDSKIPDSVHKKLETQI
NGAEEKPDTEPKDATAHNTGAGPSTSV
>A0A4S9ZIJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDGALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSIANS
APQNRVVIDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVE
FFCSHQDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLL
EA
>A0A0S2UPF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nasuia deltocephalinicola|TrEMBL
MIKFSIEFYINIYKIKEILNFNINTIYLKPLFLTITYNKFNINKKIINYLIKNGLVVLPH
LICKKKIKNFNYLLNSYFLINLKNLMIIKGDNSKNSYYYSYNIVNLIKKNYINKFNIFLG
DYIESHPNSLSYLINIKNNKIKNVIKKNVNFISQYFYNIESYYNFYDSLKKINYKIKYIP
GIMLIDDFYKIISFSNICKTELPLWIIKKLNNNKFYKWEYKKINKEIILNLILKLLNFKI
KILHFYSMNNFYLVNIICESLNNNLNL
>A0A242A886|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus sp. 8G7_MSG3316|TrEMBL
MGSKLSFEVFPTKTQAGYQNLQKTLHVLQTLDPAFVSVTCSNVTNSAEAFSIQVTDYLWH
ELKIPTIPHLAARYLNEQAVDAILDDIEGLGIQQVLALRGDEIDHRPSQGVFQYASELVA
YIKMKKPHFEIYGACYPETHPESIDRVADIKQLKAKTEAGCSTLVTQLFFDNDLFYSFQE
ACALADIEATLLAGIMPIVNRQQVTRLLQTTRTHLPRKFLAILEKYEHDPAALREAGIAY
AIDQIVDLSTNNVDGIHLYTLNHAEAAKQIYTNTRSLLSPSVESKE
>A0A258Q410|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. 35-46-207|TrEMBL
MELSVEFFPPKTPEGESKLHVVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AALKVVSDIHAAGAAVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYG
EFHHANELVEFIRTETGDWFHIDVAAYPETHPQAKSPATDVDFFVQKMKAGANSAVTQYF
YNSDAYFRFVDEAYDLGVTQPVIAGIMPITNSTQLLRFSDA
>A0A4S8SRQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYMVNIVNNDFREQRGIFPLFDELEVPDLNKEVTAPEAPQ
KVNGATNGEKHEEELKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A1M3PMF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. 60-20|TrEMBL
MAPIDENPLGVHLPLDPLPGHYSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKLFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFRDYMKKVRDLGLHEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREAGRTDALVAERLHQISEGREENQQAMAELAA
HHTPQQTH
>A0A4S9SSE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDHDTPVANGNGDKKAKARRRSSIANS
APQNRVVIDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVE
FFCSHEDWTRLRTKLDKDEQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLL
EA
>A0A1I2AZU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Succiniclasticum ruminis DSM 9236|TrEMBL
MKIINLLKGSKPGVSCELFPPKQGSQLANALEIVDTIAEQKPSFISVTYGAGGSNAGEAV
AVAAEVHKCGIPSMAHFTCINADDQGIEAMLKQLQAKGIDNVLALRGDLPEGTSLEHAEY
QHASDLAKKIKSFGDFCVGGACYPEGHPESAGLNDDIEKLKIKVDSGVEFLVTQMFFDND
VMYNYMYRLLAHGITVPVVPGVMPVTNAKQIQHICKLSGTKLPLRFRAIVEKYGDDPEAM
KQAGINYATAQVLDLLANGFMDVHIYTMNRPEIIGGILQNLSCIVK
>A0A3D1HD62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKIPELFRSGKTVFSFEIFPPKKDGSIETVYNTLDGLSDLRPDFISVTFGAGGSAAGAST
SEIAGLIKRKYNTESIAHLTCVNMTKDEIDRQIEDFREQGIENVLALRGDINPEIPPKKD
FLHASDLISYMKERSDLSFSGACYPEGHVECDSIEKDIENLKIKVDAGASHLISQLFFDN
EAFYRFLEKARAAGINAPIEAGIMPCVNAKQIQRMVGMCGASLPPKFTKMIARYENNPDA
MRSAGIAYAVDQIIDLCANGVDGIHLYTMNSPTIARKIAESVSSVIRI
>A0A094JIB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella mangrovi|TrEMBL
MAFHHAQHANSLNQSLADLNGDINVSFEFFPPSTPEMEQILWNSIQRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETNLVAAPHLTLVDASDEELLDLAKHYWNSGVRNIVALRGD
LPEGSPKPTRFANDLVRLLKSVADFDISVAAYPEVHPDAPNAQADLINLKRKIDAGANRA
ITQFFFDIESYLRFRDRCVAAGIDVEIVPGILPVTNFKQLKRFAGMTNVSLPRWLHRQFE
GLDDDPGTRSLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPQAKAE
>A0A0Q9NYI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Soil762|TrEMBL
MSPPSLIETHPNLTETAPVALSYELFPPRSPAAAESLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPEELAEIIGDLLDTGVRGILALRGDQPKD
GAPLAAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYANLISRARRAGVTIPIIPGVMPLTSLRRVTRLGELTGVE
PAPELLARLAAADSDGERLRIGVRATVDLANAALEAGAPGIHIYTFNEHQSALEVLDKLA
LPRQSRSVGRRSATLRRQLAS
>A0A7K3W1X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus sabuli|TrEMBL
MSTSRDRNLPSSALAPHHPEGLHSVPATPPDPDRGLRGPAAGRAQSIGNLLAKGPTLSFE
FFPPKGPDGEAQLWTALRELEQLAPSFVSVTYGAGGSTRDGTLAVAERIAGETTLTPLVH
LTAVEHSTTELRQVIGRLADAGVRNVLALRGDPPGADPQAEWVAHPEGVRYAAELVELIH
SVGDFSVGVAAFPEKHPRSADLRSDVDRFVAKCRSGADFAVTQIFFRAEDYLRLRDEVAA
RGCDVPIIAGVMPVTNARQIARIVQLSGQAFPTELAARFAALDGDRPADQAAVRAFGVEM
ATELSQTLLDEGAPGLHLITMNRAAATREVCANLLAGPGAATEDVA
>G1VT55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium 2_2_44A|TrEMBL
MNNAEFLKEAGVDAVTIADCPIARARVDSSLLACKLHRELALDIIPHMTCRDRNINATKA
LLFGLQIEGISNVLVVTGDPIPSEDRQEVKGVFNFNSQILAGYIRDLNETMFSNPFMVFG
ALNLNAVNFEAELAKAKRKAEQGMEGFLTQPVHSQQALINLKRARTALNAYLLGGVLPIV
SHRNAVYMNNEISGIEVDEEIVARYEGTSREEAQRLAVTISCQTIDAMRAYVDGYYLITP
FNRVEIIAELISHIHAH
>A0A559UQT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeribacillus composti|TrEMBL
MGLLQDLQNHILIADGAMGTLLYSFGIDRCFDELNVSKPEEIERIHSAYLDAGATVIQTN
TYGANRIKLARYGLEDDIKIINQKGVELAKRALQKAENKGYVIGTIGGIRSFQKSAFTLS
DIAENFREQLHVLLSENVDGIILETYYDLEELKTVLQIARKETDLPIITNVSLHEQGVFQ
NGTRLADGLKMLEELGADIVGLNCRLGPYHMLQSLEEVPLFEHAFLSAFPNGSLPRYENG
RLVYESDEHYFYEAALQFRKQGVRLLGGCCGTAPKHIRAMAEAVSNLPPVTEKEVKERNV
PIHVLPMKESQETPLPDIAKNRRSVIVELDPPKTLGLEKFLTGAKALKKAGIDAITLADN
SLATPRISNVACANIVKSRFQLRPLVHLTCRDRNLIGIQSHLMGLHTLGLHDILAVTGDP
SKIGDFPGATSVYDLSSFDLISLIKQFNEGLSYSGKSLGQKTNFTVAAAFNPNVRHLDRA
VQRLEKKISCGADYFITQPLYSEKLIEEVYEATKHLNVPIYLGIMPLISSRNAEFIHNEV
PGIKLSDSIREQMQKAGNDKEKGKREGLAIAKSLIDAAFDLFNGIYLITPFLHYEMTVEL
TEYIHEKEKAKRERKISHV
>A0A7W4CJJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. MC1862|TrEMBL
MTTPSVSFEFFPPRNLDQSFKLWETANALAPLGPEFVSVTYGAGGTTRQLTHEAVTALAS
NYGLNVAAHLTCVDASRAETMAIVDDYAAAGVREIVALRGDPPQGADRFAPHPEGFADSV
ELIEAIAARGGFSIRCGAYPEPHPESPDTSADVEWLKRKVDAGASSAITQFFFDADVYFR
FRDACAAEGVTAPIIPGILPIQNWSGAKKFAARCGASVPAWADEAFAKAGAEGERRLAVD
MAVNLCRRLIEGGVDRLHFYTVNRPQMTLAVCAGLGIAPQQAKVA
>A0A2T4QIP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus xylosus|TrEMBL
MSQLLDKLKSNILVADGAIGTILYSEGLDTCPEAYNLNHPDKVERIHRTYIEAGADIIQT
NTYGANFEKLKVFGLEHRVKDIHQAAVQIAKKAANDDTFILGTVGGFRGIKQEDLELSSI
QYHTEIQVETLVNAGVDGILFETYYDLQELTNIIEATKRKYDIPIIAQLTALNTNYLRDG
TEINHALQQVTASGADIVGLNCHHGPHHMQQSFSHIELPKGAYLSCYPNASLLDIENSQF
KYSDNASYFGKVAEQLINEGVRLIGGCCGTTPEHIQYIKSSVAGLNPVTKKDVIPITKYI
NNTEKEPKKQNLKSKVENRPTIIVELDTPKHLDTETFFRNIKKLDDAKIDAVTLADNSLA
TVRISNVAAASIIKQRYDIEPLVHITCRDRNLIGLQSHLLGLSLLDINEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKTKTNFNIAGAFDPNVRKLDGAVRR
LEKKLESGMHYFITQPVYSKEKIKEVYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEDILEQFEAVKDDKAKTKALSLKLSKDLIDTVHEYFNGLYLITPFQKVDYTLELANY
SKTITSTKQEAIL
>A0A511D750|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia asaccharolytica DSM 44247 = NBRC 16224|TrEMBL
MSDRQGASGRSGLTVFPAGEVVVADGAVGTMLHAAGIPLDQSLSELNVGRPKLVRDLHAA
YVGAGARILQTNTFDANRLRLASAGLADRVTEINIAGARLAREAAEDAPWVKIAGSVGPA
MSAALVTRIPDAERASILREQIAALADWVDLIILETFGEIESLVQGVQVALDECDVPVIA
QLTFGDDGRTLRGEEPAEVAAVLSEYDLAAIGANCTVGPAVLQEVVAELAAATSLPVSVQ
PNAGTPRRLGRALRYAHNVDYFAEAAAQLVAKGATVVGGCCGTTPAHTRAMVKSVAGLAP
LRQAREQVTDRASLRVAAPVADPEPPRVAWRFPGEFVVLSGTSAPHGEQVAQFVTQGKEL
IRAGARLLAVIDPDPPATRVNPLAAAVLLRERVEADVILQIETAGRSLSALQADLLGAHA
LGLRMLLCRTGAPRVVGDYPDPGSLWDVDSVRLIGALSALNDGVDWRGVSTSVRTRFVIG
ASLRTAAVDKRWELDRAVEKVRAGAHFFVTEVIYDVDEALNAISELRERGVDVPVIAAIA
PFGDVATIARRTHENANAAVPSALLPRLRERDPVESIDLAFEAAEKLAGHAAGILVHGPS
HADSRVVGLVSQLSRMGAAR
>A0A2B0XLU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus anthracis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIHISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6I1UBX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SZ57|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A4R7JHJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. BK208|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPGADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQAESYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A4R3VFC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracandidimonas soli|TrEMBL
MSSSGKKFSLEFFPPRDIAAQEKLVRSAKQMQALHPDYVSVTFGAGGSTRSGTVETVRMM
QNLGFDTAPHLSCIGAAKAELAELLDGYRAQGVRRIVALRGDLPSGMGGDSGEMRHARDL
VAFIREHSGDHFHIEVAAYPEMHPQSLSAREDLAHFVDKVKAGADSAITQYFFNADAYFD
FVDRLQAQGVDIPVIPGIMPITNNAQLARFSNMCGAEIPRWIRLRLADFGDDRASIRAFG
LDVVSQLCGRLLERGAPGLHFYTLNNAEVTTALWGRVVPR
>A0A379BCA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella multocida|TrEMBL
MSYAKEIDTLNQHIADLNGKINVSFEFFPPKNEKMESILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLEAAPHLTGIDATPEELIEIAKDYWNSGIRRIVALRGDEP
KGYAKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKN
>A0A511DAP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia asaccharolytica DSM 44247 = NBRC 16224|TrEMBL
MTAPGPTGGAAGTAGGLRAALAERRFAVTAEIGPPRGADPAAVAEKAALLRGWVDAANVT
DNQGAHVRMASLAGSLLAARAGVAPVMQLTCRDRNRIALQSDLLAAGALGIPHVLLLTGD
HPCFGDHPDAAPVFDLDSVQLVWAARTLRDEGRLLSGRTVAPRPEFLIGAVENPFAPPVR
FRAARLGKKIAAGAEFAQTQFVFDVPGFDRFMAAVRDRGLDGRCAVLAGVGPIRSLAALE
FVRTKVPGVYVPDEVVRRLRGVPRDRVAAEGVRLCVETIEALRAIPGVAGVHVMAFGYER
GVPEILERAGFRRDRAGRLPVGGGVGAG
>A0A4U8VTV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia cyriacigeorgica|TrEMBL
MPFSVEFNPPRDAAGEARLWRAVRTFERMHPAFVSMTYGAGGSTKDRTVRVTGELAGETT
LLPVAHLTAVGHSVAELRSLVGAYADSGIRNILVLRGDPPGDPLGEWHKHPEGVEYAEEL
VRIVRDLGDFHVGVASFPQGHHRSPDLDHDTRFLAAKLRAGAEYSITQMFFDVDHYLRLR
DRLIAMDPVEGAKPIIPELMPITSLRTVKRAEELCGRPLPRAVIERLERAAGSGPEEDAA
AVRAVGIEIATEMAQRLIDEGAPCLHFITLNFAKATGEVLTNLGYGVTAAPISA
>A0A3R7VDF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrionales bacterium TMED47|TrEMBL
MATQPHISFEFFAAKTEQGREKLHLTCEKLNRYNPEFYSVTYGAGGSTRDTTKQLVLDLQ
QQGYQAAPHLSFGGDSQETVLGLINEYQQAGISNLVALRGDLPSGIGGTTQXVHANELVA
LIREKTGDHFDINVAAYPEIHPEAESYSKDIYWLGEKFKAGANRAITQYFYNPDAYFKFV
ENCQKAGIDKPIVPGIMPLTNFQNLLRFSENCGAEIPRWLQWQLKERKDNKQDLIAYGVE
IVSQLCEALLAGGAPGLHFYTMNQWQISDSLCQNLGLDSSN
>A0A1H9KYJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces radiopugnans|TrEMBL
MTTLREILTSGERSFSFEFFPPRTDAGTRTLWGAIRRIEALRPTFVSVTYGAGGSSRDRT
VAVTERIAAETTLRPVAHLTAVGHSVAELRNIIGRYADAGVRDVLALRGDPPGDPNAPWT
PHPQGFTHAHQLVSLVKEMGDFSVGVAAFPEKHPRSPDWDSDIRHFVAKCKAGADYAITQ
MFFHVEDYLRLRDKVAAAGCDTPIIPEIMPATDARQIARFAELSGAAFPKDLARRLEAAR
GNPAAGHRIGVDHATAMAERLLAEGAPGLHYITLNRSTATLDIHRNIHRSIQSTQTPRSA
QHVLATHR
>E8KCF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus peroris ATCC 700780|TrEMBL
MSRQTPSLSFEVFPPNPEVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKRKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQP
>A0A1S1FCI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC034B03|TrEMBL
MSSQSPSLSFEVFPPNPAVGNEKIMAALKEMQDLVPHFISVTASNSKFNIEETTVRLADF
IRNDLHIPTIAHLPAVYLTKEMVTETLTALDKVGVHKVLALRGDILPDVEPQKDFVYATD
LIEYIKKEAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYD
FQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSSTAHQIYQATHTFFDK
>A0A835LLL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coptis chinensis|TrEMBL
MKVIEKIREAELENKTLFSFEFFPPKTEDGVDNLFDKMDRMVQHNPSFCDITWGAGGTTA
DLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALDAIKGNGIQNVLALRGDPPHGQDK
FVQTEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPEVIESNGVATLESYHNDLAYLK
RKVDAGADVIVTQLFYDTDVFLKFVNDCRQMGITCPIVPGIMPINNYKGFLRMTGFCKTR
VPPEIMAALDSIKDDEEAVRKYGIYLGTEMCKKILAHGIKTLHLYTLNMDKSALAILQNL
GLIDEAKISRTLPWRRPTNIFRLKEDVRPIFWANRPKSYLSRTIGWDQFPHGRWGDSGNP
SYGALTDYQFMRPRSRDKKLKEEWAVSLKSVEDIHDKFMQLCLGKLKSNPWSELDGLQPE
TKIINEQLGSINLKGFLTINSQPSVNAAKSDSPSVGWGGPGGYVYQKAYVEFFCSQGQLN
VLIEKAKTFPSLTYIAVNKEGKSISNVGPNDVNAVTWGVFPAKEILQPTIVDPASFIVWK
DEAFEIWTKGWARLYPEDDSSRTLLEQVQSSYYLVSLVDNDYIKGDLFAVFNEV
>A0A7Z1XGN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. MF30-B|TrEMBL
MTSLAEARALLLSPLGPVARAGSNHDAVRVSFEFFPPKTDEAEANLWKAIRRLEPLNPAF
VSVTYGAGGSTRERTHRTVQRIIAETALRPAAHLTCVEASRDEVDEVIAGYKAIGVDHIV
ALRGDPPGGAGIGGVYQPRADGYANATELTRAISRAGGFDVTVGVYPEQHPESPSIDHDI
DVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLTRMCGA
CGASIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRADLVYAI
CRVLGVRETKVVA
>A0A7K7X088|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mohoua ochrocephala|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A4Y1ZDJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporolactobacillus inulinus|TrEMBL
MLETYYDFDELRDVLQIARTMTDLPIITHVSMQEPGVLQNGMPVAEALEGLEAQGADVVG
TNCRLGPFHMIEALRGIPLPKKAFLSAYPNSSLPDYRDGKLHYENEPEYFKKYAVEFRNE
GVRLLGGCCGTTPVQIKAFKEGISALEPLETKVVTVHPEVVHVSEAAEPPESALYQKA
>A0A3N9UE55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria sp. SHR_NRA_18|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARIAAPSL
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIVANVSMHEPGLL
QSGQTLASALQELADLGADVVGANCRLGPYHMSKALESVPLLENAYLAAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRRGLKSLKPVTSKVVHPIL
ELAELDAAEDAGVRLTDKVKEQYTVLVELDPPRTFDTAKFFEGAQKLDAAGVDAITISDN
SLATPRISNMALAAILKQEYDIRPLIHLTTRDHNLIGMHSHIMGFHKLGIQDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALVEAGITVPVFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREADKSGTGREEGMAIAKEILDAICEHFNGVYIITPFLRYDLSIE
LTKYVQSKETIAEVSSQN
>A0A7G3BJZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomarina sp|TrEMBL
MKVTEHIKNANGNTLFSFEILPPLKGQNVQSIFDNIDPLMEFKPPFIDVTYHREEYVYKE
LENGLLQKKVVKKRPGTVGICAAIQNKYRVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKTETYFKAEKEGHHYASELVTQISDLNKGTYLDEDLLNSSCTNFCVGVAAY
PEKHMEAPSLDSDIHFLKKKIKNGAQYIVTQMFFDNNRYFEFVEKCRREGITVPIIPGLK
PIATKKQLNLIPHRFHVDLPEDLILEVVNCQNNEQVRQLGIEWCVQQSKELQKAGIPVLH
YYSMGKSDNIKAIASQVF
>A0A1J8PBX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. QHL1|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTREVVR
AVSESGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSVGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVTRLCQRLLDGGAPGLHFYTLNQAAPVLKIVDNLTD
>A0A4Q9FFE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyunsoonleella flava|TrEMBL
MKVTDHIKNANGTTLFSFEVIPPKKGKNIQDLYNNIDPLMEFKPPFIDVTTSREEYVYID
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKEEAYFKPCEGGHAFASQLVEQIATLNRGKYLHDEVEAEHYSDFCIGVAGY
PEKHMEAPSLATDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVEKAREIGIDVPIIPGIK
PIAVKRHLQLLPQVFKIDLPQDLIDAVEHCKDNKAVRQVGIEFAIQQSKELLDFGVPVLH
YYSMGKSDNIHAIAKALF
>F8E883|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flexistipes sinusarabici (strain ATCC 49648 / DSM 4947 / MAS 10)|TrEMBL
MKISDILSRKERVLSFEFFPPKKVENEHILFESIERLKRWNPDFVSVTYGAGGSTRDKTL
DWTKKIKDDYLLNVMMHLTCIASTREGVINILKELKKSGIDNIFALRGDIPEELDNIEEA
FKDFRYASDLVRLIREVDDSFSIGVAGYPEGHIECPNIGEDIENLKKKVDQGADFIITQL
FFDNRYFYDYLDMLEKYCITLPVIAGIMPIINIKQVIKFTDMCGATVPEYLKNKMMDRSP
EEMLNIGVDFATKQCRDLLENNVKGLHFYTLNRSRATINVLKNLNLD
>A0A101VGP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium BRH_c36|TrEMBL
MERKSRLLGEGEIEVSFEFFPPKTDAMEETLWKSIRRLEPMHPEFVSVTYGAGGSTRERT
HNTVARIVKETSLKPAAHLTCVDATKEEVNEVAQAYWAAGVRHIVALRGDPAAGVGESYT
PTPGGYTNAAELTKGLKEIAPFEISVAGYPEMHPESGYEEADLDNLKAKIDNGADRIITQ
FVFDQELYLRYLERVRAAGIWVPVTPGIIPIHNFPQVANFAGRTGASIPAWLRRRFEGLE
NDSTTTHLVAAAVATEQVMLLADHGVKQFHFYTLNRADLVYAICHMLGIRPLPASSQASA
NAA
>M2U5B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pacificimonas flava|TrEMBL
MSLQDTEHGRAFARPLFADLAGDIDVSFEFFPPKTEKMNQALWQSIETLAPLAPKFVSVT
YGAGGSTRDRTHATVARIARETPLTAAAHLTCVDASRGEIDDVAREYWDAGVRHIVALRG
DPPRQGERFAAHPDGYDCAASLVEGLKKVADFEISVAAYPEVHPESGDARACLDNLKRKI
DAGASQAISQFFFAPETFLRFRDAAAAHGIDTPIVPGILPVSNFAQTKTFAAMNGADLPG
WLERLFEGLDDLQDARKLVAATVAAELCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLR
AGASPVPARLESAAA
>A0A0Q6VJI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium sp. Root344|TrEMBL
MDGFSLEMTGKDLAGLEEARVSVPPGTRVNVTFLGNEDLEMRVAAAAAVARAGFVPVPHI
SARRLVSQAQLEGFLDRLQAVGATDHVFAVGGDPSIPEGPYPDALSVIRSGVLQRHGVQE
VAIAGYPEGHPEIADEVLWEHLEAKHAALTEQGLATVLLTQFAFDTGPVTAWIREVRSRG
IDAQIRIGTPGPAGVRRLISFARRFGIGANAMIVKKYGFSLTNLMGTAGPERFIGGLSTE
LDAEPAAGDVKLHFYTFGGLPATSEWARSYVADIQRQETA
>A0A8I0L3Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. citri|TrEMBL
MFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKTIEIAKKIKNQYNVEPVV
HLTCLCYNKAEIDEFTRQLSYEGIENILAL
>A0A7W0M7B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MTHLRDIYSDGRFGLSVEIFPPKTPAGDADLLATLEELSRYRPAFVSCTYGAGGSTRGRT
IDWCRAIQERFGLPATAHFTCVGSCRAELLDWLREAQNAGVRNIMALRGDVPRGETTFQV
ADDGLRYAAELVRLIKQNFAGFGIGVAGYPEKHPEAQSIEIDREHLRQKVANGADAVFTQ
LFFVNRNFFRFRDAAAKAGIDVPIIPGIMPITSFDRIKRITAMCGAVFPGDLAGRLEDAK
SDTDAQFKIGVEYAIEQCRGLIDAGVPGMHFYVLNRSQACSRIFDALGFPSTVGSM
>A0A7W6TZK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. CIR48|TrEMBL
MTDLTIPARADGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTPYSSHPDGYQSSPELIAGIKKRHGDIEVSVSAYPEKHPEARDFDDDIDTLKAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARAFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A498GD92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula sp. Atlit-7R|TrEMBL
MALGTHAVSNSQGVQTLLTSARFELMPFESFDEEITHLPDDATIAITTSPQLGIEKTVEK
TEQAAAMGYDVVPHVAARYVEDRAQLEAIAERLDQAGITDIFVPGGDREEPAGEFESALD
LLEALADTEYDFEEVGITGYPEGHDFIDDETLAESMARKAPYATYIVTQLCYDPDAVLEW
VEEIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDNDYNIRGIHIYTFNQTPDTEKWRHKRLDS
>A0A7V4PBD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MFYPDRRFTLSFELFPPKGADGEAALWQNLGELMRFGPDVVTCTYGAGGSTRDKTLDIVS
QVRQRYGVRVASHLTCVGSTVEQLRAYLAEAQARGIENIVALRGDPPRGQTAFQPVAGGL
RYASELVTLIRGEFPHFGIAVAGYPETHQEAASPQADLENLRRKVAAGADCVLTQLFFDN
ADFFRFRSRCRELGMKVPVVPGILPVTNLAQIQRIASLCKARLPEELVAQLSRQEDPEWQ
FQVGVRWATRQVQELIDAGVPGLHFYVLNRSPATAAVLSDVKRP
>F5RG83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloversatilis universalis (strain ATCC BAA-1314 / JCM 13912 / FAM5)|TrEMBL
MTDNPTRICSVEFFPPATEEGAEKLRATRRQLRQLNPSFFSVTYGAGGTTRDRTLETVLE
MKAEGLNAAPHLSCIGSTRDNIRQTLERYKEEGIHHMVALRGDLPSGVVDPGDFRYANEL
VEFVREETGDWFHIEVAAYPEVHPQARSAAKDLQAFVRKMKAGADSAITQYFYNTDAYFA
FVDDARAMGVDAPIYPGIMPIANFSKIARFSEACGAEIPRWMQRKFEGFGDDAASVKAYG
LDVVTTLCERLLAGGAPGLHFYTLNQAGLTSTIWQRLGL
>A0A7J8PGV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium raimondii|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGI
>A0A4S0JPJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2E.F.Ca.ET.209.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVIREFVDFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
AGSAAA
>A0A089Q237|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cedecea neteri|TrEMBL
MSFFHANQREALNQSLAEVAGHINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPQFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNSGIRHIVALRGD
LPPDSGKPDMYASDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLRRKIEAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFRQAKKFADMTNVRIPSWMAQMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A6J4TM55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Solirubrobacteraceae bacterium|TrEMBL
AHRSAARPQRAARLLVRVLPPQDGRGRAQPRARAAGAQAARPRLRLRHLRGRRIHAREDD
RPRLADQGGLRPGGDGPPDVRQRHHGRAAAHAGPDARRGRGQRPGPPRRPAARPGALDED
GRRPGVLPRARRAPARGLRLRDRRCGVPRDAHPRLLAGGRPAVPQGEGRRGRAVPHHADV
LRQPLLLRLRRPRAGGGDRRADRAGRHADPEPRRHQAHDRAVGRAPARGPARAARGPARE
RRGGRRARRGVRHAPVRRSSARRRAGHPLHHPESLPRHTCDPQRPPAHAALAL
>R7N5K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:95|TrEMBL
MKITSIFEKEEITVSFEVFPPKTTTNYEAVEKAALGVAALKPSYMSVTYGAGGSTRGYTI
KIAEKIQKEQQVTTIAHLTCVGATKADIHAALGQMKEAGIENILALRGDRPKDFEGDPYV
DYHHASELVETIREYGDFCVGGACYPEGHPDAATKKEDILNLKKKVDAGCEFLTTQMFFD
NNIFYNFLYKAREAGILVPVIPGIMPITRANQVANAVRLSGCNVPERFRSIVDCFGDNPA
AMQQAGIAYATDQIIDLIANGVNHIHVYSMNKPEVAKGIYDNLSAIIH
>A0A1M6BE20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malonomonas rubra DSM 5091|TrEMBL
MSRLAEKLSQQQFVVTAEIAPPKGVDVGPALAKAELLRDMDAINITDNQGACMRMSPLAL
AGQLVQHGYQPILQITCRDRNRMALQSDLLGASALGIENLLLLTGDHPKFGDHKASCPVF
DLDSVQLLQAVSGLEHGVDMAGKKLSQPPQFFSGAAVAPAAEPQLLTLKKFKKKVACGAR
FFQTQAVFERTKLESFMAEARLYQVPVILGVLLLKNVRMADFLNRNIPGVQVPQDLLQRL
EDAPDSLQEGVAIAREMVALAREFCQGVHLMTFGHEDLIPQILAG
>A0A212TCY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter victoriensis|TrEMBL
MELSVEFFPPKTAEGAAKLRSVREQLATALKPTFFSVTFGAGGSTQDGTLATVKEIHEAG
QQAAPHLSCVGSSKEKIRELLAQYKALGINRIVALRGDLPSGMGQYGEFHHADELVSFIR
SETDSHFHIEVAAYPEMHPQAKSMTDDVLRFANKMKSGADSAITQYFFNSDAYFRFIDEA
AKLGVDQPIVPGIMPITNSTQLLRFSDACGAEVPRWIRLRLQSFGDDTASIKAFGLDVVT
DLCDQLTVAGAPGLHFYSLNQADTTLNIAKNLNLI
>A0A4Q1RGW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia faecicola|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMFGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLEEGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMVKFMNNNVAGIHVPDEMIEE
LKADKERTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A502TGT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-8-9|TrEMBL
MTIRQIDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHLLHDEITETQVDMVK
TAH
>A0A261XVQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifiguratus adelaidae|TrEMBL
MKVIDKIREAESEGRPYWSFEYFPPKTAQGVQNLYDRMERMYRLGPEYIDVTWGAGGTTS
DITSEIVSTAQSVYGLETMMHLTCTNMPREKVDEALKNAKACGCQNILALRGDPPKGQTE
WEACEGGFTYAVDLVKYIREQYGDYFGIAVAGHPEGHIEVTDREQELIHLKEKIEAGADM
IITQLFFDVDMFIDYVKRCRAVGIKCPIIPGIFPIQSYNGLKRVISFNNNHVPDEIWAAL
EPIKDDDAAVKEYGIQLAVDFVKKMRAAGVNGFHFYTFNLERSTRLTLERLGFVPSLEAV
KPLPWNPSLHKKRAKETVRPIFWKNRTKSYIQRTESWDEFPNGRWGDSRSPAFGELDGYG
VSLKYPKKECLEMWGYPSSSDDIAALFARYCKGSLNSLPWSAQQLDPETEVIRQRLAAIN
LLGYLTINSQPAVNGVKSSDRTYGWGPNNGYVYQKAYLELFVAPDDLGGLLKKIDSDPEI
TYYAVNKQGDLKTNSKSDGPNAVTWGVFPGKEIVQPTIVEVTAFMAWKEEAFELWNEWAQ
IYDEGSPSRTLINDIANNYYLINIVHNDFQDENGIWRLFNLEIDGDLFRKLTTITSDTVS
R
>A5IKF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga petrophila (strain ATCC BAA-488 / DSM 13995 / JCM 10881 / RKU-1)|TrEMBL
MRKSLETGKCVVLEVLTPRGTNLDKFMEFTEEAWKTGIDAFTVTDMPMGRVRMAPWAASH
LLVESGKDVLMHFTRNTRNMIRIQSDLLGCHALGVKNLLLLSGDNPSHGDYPETTSVNDI
DILDLIRLTKLMNEGTDLAGNKIYGKTDFFVGGALNPFSDEDVERAKQKIEAGVDFLVTQ
PLFNSEVAKKIKEELNTKILASIVFFENAKQMSYFSNVPGIEIPDEIVNSAEKGDDYLKE
KSFESVLRFVEETKDVLDGFYIVAIVKDLEKIRKVVEIAKS
>R7AEN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:379|TrEMBL
MKTCELFRDHTVLSFEIFPPKPTSPEDIIYRTLDGLWDLHPDFISVTFGAGGGANNQKSL
EIASAVKHQYGIESVAHLPGINLTRSEVLTMLEQMQQQGIENILALRGDVLPDTQPRGEF
RHADELISFIREHGDFNILAACYPEGHTESLDTVTDLRNLKRKVDAGANQLVTQLFLDNR
YFYEFREKAELVGIHVPIEAGIMPVTNKKQIERMVQLCGVHLPEKFMKVMNRYEHQPEAL
QDAGIAYAIDQIVDLITQGVDGIHLYTMNKPYVARRIYEAVHRLLYA
>A0A099NXW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pichia kudriavzevii|TrEMBL
MSVKITDKIASLGKDEPFFSLEFFPPKTESGMRNLYARLGRMSLLGPLFVTVTWGAGGTT
AEKTTDLAVTCQEELGLTTCMHLTCTNTPKSVIDDALKKAKASGIRNILALRGDPARDTS
ISHGIGEFKYAVDLVRYIREQYGDYFCIGVAGYPEGHADGSFEELTQDPRKDMPFLVEKI
KAGADFIITQLFFDVDKFADFEALVRSQPELRDTVIIPGLLPINGYNIFQRASKLSHASI
PSKLLAKFPTEVQNDDDVVKDIGVDVLVDIIDQIYKKTDNRVKGIHFYTLNLEKSIAQIV
NKSDHLYKVVAKKESEIEADESSSDDDIDDAITTAKRAAYANRFNTTNKVISDIKASTSL
KMQHSNSSSSQLKKLISISAGHGVLGKDATWDDFPNGRFGDSRSPAYGEIDGYGPSLKVT
STKAYELWGYPKTKKDISKLFVNYLLKKLNCLPWSELSLSPETALIQEELINLNELYYFT
VASQPAVNCASSQDKIIGWGPSNGYIYQKAFVEMFVSKKDWNEKLLPKISKCGSSVSYYY
ADSKNYFDTNLPPNASNCVTWGVFPNREIVQTTIIEEESFKAWTEEAFEIWKEWRLLYKK
DSDSAKLIDTILNEYYLVTIIHHEYPNESALWELLLDDE
>A0A2K4GFR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FW300-N1A1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLSEYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGNHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A2V6RT39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MASSNPLRAALAAGRFCYLVELVASRLAREARLLEIASGLARVPGVVAGSITSYAGGAPG
HDPLRIGAAARARGLTPSLHVTCVSLDRHGLRKLLEDAAALGIENVFAMSGDWPTAPVGQ
DRPPAVYDIDAVQLVSLIAGLRRAGPPFHVAVAVSPFKYLESDCVYQYLKLEKKARAGAD
YAITQVGWDAEKFRELKRWVDERGLRLPLVGNVYLLGPRTAAKMARGEPPGCWVPPELLA
LVERESAAADGGLGARLERAARTIAVLRGLGYAGAYIGGTQDPELIARLIARSDVLAPRW
EEFAAELRFGRPDGFYLYREAPRARGPRREAIPLVLDTLGRLFPVRRETWLRKGLRGIFR
AIDRSRGLARAVERLEFALKQPAFGCQACGNCVLGDLEYVCPLTCPKHERNGPCGGTAHG
RCEVEDKPCIWGAVYARARAAGRLDGLRAYIPPADPGLAGTSSWINYFLERDARPRAGL
>A0A353V2Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFSRRLAAGPLLCDGAMGTMLYARGVPLDACFDVLNVNAPRLVQAIHGDYVAAGADC
IETNTFGANRFKLAVHGLDGRVHEINLRGAKLARDLRESAGRDVLVLGSMGPLGKYLAPL
GTVTADEARAAFREQAEGLLEGGVDAFVVETFSDLAEIALAIEAIRVVTDLPIVAQMAFT
DEGVTFTGRAPAEVARTLAALGVQALGASCSVGSSTLYEVLERMLPAAGGVPLAIQPNAG
LPSRIGERLIYLSSPAYMADYAGRMVDAGARLVGGCCGTTPPHIAAMREVLDRRRPSPRP
AARPRVHVSPPAAREAPGLHTERPPTLLGRKLAAGEFVVTVELDPPRGHTVEKLVQGAKL
LRERGVEIVDINDGSLGRVRMAVLPTALLVREATGLDINMHFTCRDRNLMGMQADLLGAH
ALDVRNILAMTGDPPRAGDYVDATAVFDVDGIGLIEIVRRMNEGLDATGSSIGEPTSFWV
GAALNPAASDVERELERFHRKVRAGARWVQTQPVYDLAALDRFLARAGEVPVPVVVGILP
LHSFRHAEFLHNEVPGIDIPEAVRHRLREAGDGALRVGIEMAQALVHAVRARYAGAYLMP
SFGRFEVVAEVLDALH
>A0A7L2NQ37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pycnonotus jocosus|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKENSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAETYEADLRHLKEKVFAGADFIITQLFFQPETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFFTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKTPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7L1TQ19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phainopepla nitens|TrEMBL
MVNETQHSCSGSSSSRSDGSSSGSEGSKDSSRCSTPVLDADRHERLREKMRRRQEAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCSNQTKDDITGHLQKAKRLGLKNIMALRGDPTGEEWEEEVDGFNHAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFFKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A8I1DEN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoactinomyces intermedius|TrEMBL
MGEQGLLQCLQHSLLVGDGAIATFLYQQGVSIGHCTEELVLSNPFLIGEVHEAYYRAGAR
VIETHTFGANRERLSRYGLESKVTRLNREAVHIAKESIGSDAYVLGVIGSICAGKVPVYD
EEEYRAMYEEQAVALLHGGVDGILLETFLDLKELQLAVEVIRPLTTLPVFAQLSMMEIGR
TRDAFTISEAFEKLASLGVNGVEINCRFGPVEVLRTLEKTIVPEQMILTAFPNAGRLGMS
NGELHYKSAPDYFEETAGLLIDQGVRLLGGCCGTTPEHIARIAKVLKGKCPVQRKNPPQD
GYKLSSHETIVLQRRTKPTVVQKVRNKQRTIICEFDPPKDLDIMRFLQGAKKLKQAGVDA
VTMADNSLATARMSNLALGAILKKYDIEPLVHVACRDRNLLGQQSHLMGLHALGIDQILV
ITGDPTRMGDLPGAHSIYDVTSVEMIRMVKQLNEGISFSGRKLKQKAQFVVGAAFNPHVR
KLDAAVKRLEKKIEAGADFVMTQPVYDPDGVIRVHEATKSLGIPVFIGVMPLTGYRNALF
LHNEVPGIKIPEDVLKRMEKTTDRQSGKSEGVQVAKELLEVAMEKFDGIYLITPFSNWQM
TEELTHFIRWRDKEMHARLQSHTHA
>A0A8J6W1S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichocoleus sp. FACHB-591|TrEMBL
MLNSSLFPSPSCFRQALQSGEFLVTAEVAPPKGGNAAHMLQMALVLKDRVHAVNITDGSR
AVLRMSSLAASIILLQHGIEPICQVACRDRNRIGLQADLMGAHALGVRNILALTGDPVKA
GDHPDARAVFDLESVRLLQLISKLNQGFDCNDKLMPDGPTDLLVGAAVDPQLNSWSGLQR
RFDRKLAAGAQFFQSQLICDFERLEKFMTQIAVGSNKPVLAGIFLLKSAKNAQFINRNVP
GVSIPDEIIQRLERAADPLQEGITIAAEQVKLARELCQGVHMMAVRREDLIPQILDLAGI
PPITQAAPAFQPAGS
>A0A8C2Y832|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coturnix japonica|TrEMBL
PDRLVAPSVPAPPVCGSPSPRSTAGSSSTSPRRTPASSSSKSDGGSSSGSESSKDSSRCS
TPVLDAERHERLREKMRRRQDSGDRWFSLEFFPPRTANAAVNLISRFDRMAAGGPLFIDV
TWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNI
MALRGDPVGEEWEEEVHGFNHAVDLVKHIRSEFDDYFDICVAGYPKGHPEAESYEADLKY
LKEKVLAGADFIITQLFFRSETFLKFMRDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSK
LEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEVL
KRLGIWNEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSS
SPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGHRVTCM
PWNDDPLATETSLLKEQLEKVNRRGILTINSQPNINGKPSTDPIFGWGPSGGYVFQKAYL
EFFASSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPT
VVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLW
QVVDDTFELLNSPPQQ
>Q0FF75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium HTCC2255|TrEMBL
MDINHKDFGLSFEIFPPRNLKASFKLWRTIEVLEKLNPNFISVTYGADGSTRELTQSAVS
VIAKEYNIDVAGHLTCVGSSKKEIMDIALEYGKAGARKIVALRGDSPEDQGSENHETDNF
SSSVELIASLKKNTNFELYVAAYPNVHPNAQSEKSDLDVLKAKFDAGADSAITQFFFDKE
DFLRFRDKCNAAGIYQNIIPGILPVENWSKTKIFAKRCGMDAPQWMSKAYENCKNNEEHD
LLSQALCTEMCNELMQEGVNNLHFYTLNDPKLTQKVCEALGRKVTSTNITKVA
>A0A7Z9IX06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
RVARRYWEAGIRHIVALRGDPPDGQGKYVAHPEGYNNASDLVRGLKMIGDFEISVAAHPE
GHPEAKSIEADIENLKRKVDEGATRGITQFFFQPEHFLRFREKTQKAGLSIPIIPGILPV
TNFSQVRRFSKVCGASIPHWMSTLFEGLDNDPDTRLLIAANIAIDLCRILKAEDVTNFHF
YTLNRADLTYAICHVLGNSRNTQPKIAL
>A0A7C7GKF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MLAKAEPLRGIVDAVNVTDGASARVHLSSVISAAILNANGIEPVVQFTCRDRNRIALISD
LLGVGAQSIHNLLILTGDDPTVGDQPQAKPVFDLKGHELITIAHKMSQD
>A0A5M9NNK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. HV4-5-A1G|TrEMBL
MSLLKEAFKKGDFAVTAEMAPPKGTDLSHLIECANNVKGRVHGVNVTDFQSATLKATSLA
TCKVLKDAGLEPVLQITGRDRNRIAIQGELLSAGVFGIENVLALTGDYTGVGDHPGAKPV
YDLDSVGILQVASALAAGKDMSGNDLNGVPKFYLGACVTPKYEPLELQIIKMRKKIKAGA
KFFQTQAVYDIDILREFKEKTKDLNAKIMIGIIPLKSAGMAKYMNKNVPGIFVPEELIDR
MKNAEDKVKEGIKISAEFIRRIKEEKLFDGVHIMAIGAEENVPLILDEAGL
>R5PI56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odoribacter sp. CAG:788|TrEMBL
MKITDILNREASPFASFELVPPLRGSDVHKLYESIEPLMDFNPPFLNITFHRDEIEFRPK
PDGTFEKITVTKRPGSVAIAAAIMKKFKIEVVPHLICGGASKHKLENDLIDLNFLDIQNV
VALRGDAIPGQKFFTPEPDGYRYSCELVEHIHNMNRGKYLDTTLTDTVPTNFCIGVAGYP
EKHYEAPNAETDICNLKHKVQAGADYIVTQMFFDNTRFFSFVEKCRAAGITVPIIPGLKP
ISTQKHIEMLPRTFSIDIPEELMKEIRKCKDNKEIYQVGIEWCTMQSKELLSRGAPAIHY
YTMGKADNIRKILTAVF
>A0A399S2N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter oryzae|TrEMBL
MKVTDHFKNADGKTLFTFEILPPLKGENLHTLYTHIDPLMEFKPPFIDVTYHREEYIYKQ
RENGLLEKRSTRKRPGTVGICAAIQNHYKVDTVPHLICGGFTKEETENALIDLHFLGIDN
VLVLRGDCVKSEQRFIPEPDGHNYASELIEQVVNMNNGCYLDDEQAYNNGTDFCVGVAGY
PEKHFEAPNLKSDLRWLKQKIAMGAEYIVTQMFFDNQKYFDFVNLCRQEGITAPIIPGLK
PLTTKTQLCLLPSLFHIDVPCELADAVEACADNKAAAQVGVEWAIQQSKELVEFGVPCLH
YYSMGKSGSVRKVAEALF
>A0A5N5NMD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pangasianodon hypophthalmus|TrEMBL
MVNQREENGWQSFKSDSSGASNSGESSKESSRCSTPVGEADRGNRLRDKMRRRIESGDRW
FSLEFFPPRTAGGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHMTCCKQTKEKLTFYLSKAKHMGLKNIMALRGDPVGADWEEEEGGFNYAVDLV
KHIRSEFDDYFDICVAGYPTGHPEAESYEDDLKRLKEKVDAGAHFVVTQLFFRAETFLKF
LKDCRAIGITCPILPGIFPLQGYHSLRQLVKLSKLEVPEEIMKVIEPIKDNDAAIRNYGV
QQAVEMCKVLLNSGDVPGLHFYTLNREVATTEVLRQLGLWAEDPRRPLPWTVSAHPKRKM
EDVRPIFWSTRSKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLK
MWGEELMSEQSVYEVFTNYITSQPNQNGHKVMCLPWNDDPLAPETNMLKEALEKVNRRGI
LTINSQPNINGKPSSDPVVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYH
IVNVRGENITNAPDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWGKLY
EDESPSRMIIQYIHDNYFLINLVDNDFPLDSCLWQVIDDMFELLSAPPETLEENSN
>A0A1M6NI98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas caseinilytica|TrEMBL
MKFDDEPVPGYSLPVLPGHVSPGRLERVLRAGRFAVTTEIDPPDSADPAEVLRRAAIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYATILQMSCRDRNRIAMQGEILGAAAMGAC
NLLCLTGDGVQAGDHPHARPVFDLDSLSLLEMARRMRDESCFESGRPIDSPPRVFLGAAA
NPFVPPRAWRAQRLAKKAAAGARFIQTQYCFDTATLRDFMAEVADYGLLEGPDRLHVLVG
MGPLASARSARWIRDNVPGIHIPDAVIRRLEGASDQREEGARLCRDILQEVREIEGVSGA
HIMAYRQEATVARIIEETGVLEGRVPWYPGRDDPTELNPEAPEAAGDLPAAASS
>A0A1N7ET00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. RURRCA19A|TrEMBL
MTVLPLLDACPKRMEYGPCGGVGFDGSCEIDASHSCAFLPRGTVPWTGIDRATLVDPGPR
TAAATETLASLGTRPWVVADLPARALSVASIDSCAAVLAGEVDAVLAGDAGTARVQFPPA
YRAHLLQRAGLRVWTGLNMRDRNRVAIEGELAALAVEGVAGVHCVTGDHTRTGDRPDAAP
VFDLDSTEAAALARAAGHVVSVAASPAAPPVDRRDARLREKLHAGADVCFVNHAGGAEPV
RRFIDAVAAPVSYIPCVPVVVDHASADVLESFTTLVLPDGFLERVRSARDPRAEGIALAV
ALAEELLALPGVVGVNLSGGRDGGEESFAEAQAEIARRLR
>A0A522W2Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MDARLPSPSGWRPSRNDERTSIVTVSERILPLHVSVSFEFFPPKTEKMQEQLWESVARLA
PLRPGFVSVTYGAGGSTRERTHETVLRLKRDMGLSPAAHLTCVAASRDEVDEVARHYWRE
GIRHIVALRGDPPDGGKYAPHPEGYAYALDLVKGLRKIGDFEISVAAYPETHPEALSPEA
DLDNLKRKIDAGATRAITQYFFDPSTYLRFMDRVRKAGITVPIVPGILPVTNFAQVVKFS
KACGASVPNWMADLFQGLDDDPDTRRLVAATATSELCRALAGKGVEHFHFYTLNRADLVF
AICHILGVRPKES
>A0A672ZJA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaeramia orbicularis|TrEMBL
MVNQVPRGDGSWQSFKSDSSGASTSGGDSSKDSSRCSTPVLEADRSDRLRDKMRRRTESG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTTHKITGYLEKAKRLGLKNIMALRGDPVGADWEEEEEGFNYAI
DLVKHIRSEFDDYFDICVAGYPTGHPEAGSYEEDLQHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIQQAVQMCRVLLDSGKVSGLHFYTLNREVATMEVLRQLGLWTEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSTKDA
LLQMWGDELMNEQSVYEVFTCYITAQPNHRGHKVMCLPWNDEPLAPETNLLKEELEKVNR
RGVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRV
NYHIVNVHGQNRTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKATPPVMTKVWSE
WLSGRCLSVSHICHIHYSKKVKDHFFICV
>A0A838H6T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriales bacterium|TrEMBL
MPGRTPSRLPDRAATVPDLMAASERTFSFEFFPPKDDRGEAQLWRTIRELEPLRPTFVSV
TYGAGGSTRDRTIRITERIASETTLTPVAHLTCVGHSRAELRQVIGAYADAGVRNMLALR
GDPPEGPGAPWRPTPDGLTYASELVALVKELGDFSVGVAAFPEGHREALTLDADASAMKA
KADAGADFAITELFFRPADYLSLVDRSIAAGVAMPIIPGIMPITNLGQIKRFAELSGRDV
PREVVARFDKITEPADVRREGVAIATELCDELLREGAPGLHFYTLNRSKATREIFAALTA
FA
>A0A7J9VND9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriales bacterium|TrEMBL
MRNSSRRAGLRAALESPRYEIIPAAKVEAAVFELPRDVTITVTASPTKGLDATLECAERV
AGQGFRTVPHVSARLVVDYAHLSEIAARLAAAGIREVFVPAGDADPPAGRYDGSHKFLLD
LARLGSPFAEVGITGYPESHPAIADDVTVQAMWDKREHATYVVSNLCFDPAVLRRWVDRT
RARGITLPIQMGLAGPVERTKLLAMATKVGVGESTRFLSKHGSRFARIAMPGGYSPERML
NRTKDLLNDPVAHVVGLHIFTFNQVAETERWRQQMLGRVAGVGAAS
>A0A5C0UBL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MSLLAQYFAQQQFCVLVEYLSSHQAQWPVKAQFAGFPAAMTLADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDAKTRGQKNLLLLTGDKLKQHCYSHDLEPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMAAL
QDAHAFLARHQYAQKMLACVMPLTLARAKFMLKHNVAGIVITPHMLQVLQQEKEQGLSDR
VYVRCALQILMCRHLGFAGVHLSACHQPEEQVLLESYIEEYRHLSFAECEQLWNTLWQVQ
TSTEFHPKLAYYSRPATSSQIIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDRTKANN
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTAILKEKLIPTVSIAVRGTSSWKNWYVESAD
>A0A5R8Y3Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Halarcobacter] arenosus|TrEMBL
MLTEKIRNKESGIVLYGITPPKVKHTQEEIKEIASRHVDRISKLDVDGLVLYDIQDESDR
TDEKRPFPFIKTLDPCEYSHNYLQELKTPRIVYRAVGNYTNETFTKWLEFTRQNQVHSVF
VGAASHEQKNPLTLKDAYTLKKEVNKNLCLGGIAIPERHMSKHNEHIRVVSKQNSGCEYF
ITQCVYDVHAAKTFLTDYVKYAKENSLELVPIIFTLTPCGSAKTLDFMKWLGINVPNYLE
EELKESGDILQDSVKLSKDIFEELYTFGLKKGIPIGCNIESVAIRKEEIDASIELLNEVK
KIIKNHK
>A0A385NRQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. Y1|TrEMBL
MSLLDKLKKDIVIGDGAMGTLLYSYGTDSCFEELNLSHPDDILNIHKAYLRAGADVIQTN
TYAANSLKLQRYGLEDSVEKINRAAVKIAKQAITNESFVVGTIGGNRGIRHNSFSLEEIV
QSFSQQLHYLLLEDIDGLLLETYYDLDEIEAVLSIARKETNLPIIAQVSMQVPGIMQNRT
PINEALLRLENLGADVVGVNCRLGPHHMLESLEQVELPKTALLSAYPNASLPTYTDGKFH
YEGDADYFRKSAQEFRAQGVRLLGGCCGTTPAHIEAFASELKGTSPVTEKQVEVKKEVVQ
VKSVQPKRTERPLQEIVKERSSVIVELDPPRKLNTKKFFEGAQALKEAGIDAITLADNSL
ASPRICNTSLAQLTKTNIGLRPLVHITCRDRNIIGLQSHLMGLHTLGLHDILAITGDPAR
VGDFPGASSVYDVSSFELISMIKQFNEGLSPTGKDLGEKGVFSVAAAFNPNVKYIDKAVL
RMEKKAKYGADYFITQPVYSEEKLLEIYHATRHINEPIYIGLMPLTSSKNAEFLHNEVPG
IKISDSIRELMASLKDDPVQSANEGIAITKSLIDAASELFNGIYLITPFMRYEMTAQLAT
YTNTINSQVLRRKLNANSIVK
>A0A077N8P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus bovienii str. feltiae Florida|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPSTTTMEQTLWKSIERLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKDKTGLDAAPHLTCIDANREELRNIAHDYWESGIRHIVALRGD
LPDSSGKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A358XSZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp|TrEMBL
MKIIDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTDGGHAFATDLLEQVTDMNKGKYLHEDIITSEKTDFCIGVAGY
PEKQFESPNFNTDFKYLKQKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVAACKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLA
>A0A2C6CUE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lewinellaceae bacterium SD302|TrEMBL
MKVTDYFKAAEGETLISFEVLPPLKGGSMQAIFDTLDPLMEFKPPFIDVTYHREEFVYKR
RESGYYEKTAIRKRPGTVGICASIMHRYGVDAVPHLLCGGFTRQETENALIDLAFLDVQN
ILALRGDARKFEGKFIPEKEGNNYAIDLVRQIDDMNQGKYLDNLVEDGTKTNFCIGVAGY
PEKHFEAPNMGMELQRAKEKIDAGADYIVTQMFFNNDKYFEYVDACRAAGINVPIVPGLK
PLTKLYQLNSIPRLFHVDLPDDLVNAISSAKDAAGRKQAGVEWCIAQSKELKAKGAPCLH
YYTMGDSDTIAKIGKAVL
>A0A5N7E0E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus pseudocaelatus|TrEMBL
MFPFPLIGGPVKLRPKPFPPRWISPQSSFFNHHLSRNFAGTDSGNKMEKITDKIAALPPD
ANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGTTAQRSLELAEICQRQ
LQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNRDFT
FAVDLVRYIRQKYGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTQAGADFIMTQ
LTYDIEAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVQIPPQILSKL
EEVKHDDDSVKRIGVDIITNLVDGMRDIPCPGLRGFHFYTLNLEKTVSFILERCDLIPPY
SEDFDAIEDGGDISAMDGAQLRSLTRRRASSINSLPHNRVIVDKLQASEGSSKASVSHEA
PATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLH
VPPSVAHRIWGFPVSREDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELL
QLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLL
QKHGHEKLAWFAANGKGDFESSLPAQTSDADPIEMNPNNVNTVTWGVFRGKEIVTPTIIE
EVSFRAWGEEAFRIWDEWRRIYPRNSATERFLNETKDDVWLVCVVGQDFGAGTEMGSEEE
EDEKKFMWRVLLNAK
>Q1YTA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium HTCC2207|TrEMBL
MFDDEPLAGENLPILPGHDSPGRFERILRAGHFAVTAEIAPPDSADPQEVFDRAAQFDGY
VDAINATDGSGANCHMSSVGMCALLTRRGYSMIMQISCRDKNRIAMQGDVLGASAMGVSN
ILCLTGDGVQSGDHPEAKPVFDMDCMTSLQMLRGMRDDGEFLSGRKITSPPRVFLGAAAN
PFAPPFDYRPLRLAKKVAAGAQFVQTQYCFDIDMLKTYMAKVRDLGLDKKVFILPGVGPL
ASAKSAEWIRNNVAGVHIPDGIIKRLAGAEDQKQEGVNICIDMINEVRDIEGVSGVHIMA
YRQEHRIAEIVEKTKLLGDRIPWHPSR
>A0A2T9VAN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. HN503E2II|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A3S4CD29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia equisanguinis|TrEMBL
MLDDNLRASRKTADQRPPLQLSFEFFPPKTDAMEERFWESIHKLAPLQPRFVSVTYGAGG
STRERTLRMVRRITADTGVAAAAHLTCVGASRDEVDEVVRGYREAGVKSIVALRGDPPEG
VGQPFTPHPDGYRNAADLVAGIRRIGDFDISVAAYPEKHPQSVDWDADIDNLKRKLDAGA
SRAITQMFFRNADYLRYLERARKAGITAPIVPGIQPIHSFKQISGFAARCGASIPDWMAE
RFAGLEDDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRS
>A0A258TV79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium 28-61-23|TrEMBL
MTERTFSLEFFPPKTPEGMDKLRETRAQLALLKPEFFSVTFGAGGSTRDRTLETVLDIQA
AGLAAAPHLSCVASTRESISEILETYRANGIRHIVALRGDLPSGMAEPGEFRYANELVSF
IRQETGDWFQIEVAAYPETHPQARSYRDDLLNFKRKAEAGANAAITQYFFNPDAYFNFVD
DCAALGVTLPIVPGIMPISNFSQLSRFSAMCGAEIPRWLSRKMESYMDDTASIKAFGLDY
VTGMCDKLLRGGAPGLHFYTLNHAGLTSTIWHRLGLNA
>A0A370CBL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus niger ATCC 13496|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVEQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDTSSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A416C7Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF37-5|TrEMBL
MIKDLFHTNRPTYSLEVFPPKKDADVSVIYDALDEFKTLHPSFISVTYGASGNTAENTFA
IASYIQNQCGIEALTHLTCAAIPDRLFLKNFLTNLYRNGIHNLLALRGDKPQWMSDEQFD
ARYYDHASDLVTDVKEMFDFSVAGACYPEVHQEAASLSEDIANLKIKVDKGVDFLITQLF
YDNETFFRFLDEARNAGITVPILPGLMPITSAGQVKNIIGMSGTKIPKELADAIEKYKDN
PADLKKAGLDYSKRQMENLLAHGVDGIHLYSMNKVEIAKAIYE
>A0A2E2BQD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonadaceae bacterium|TrEMBL
MSAHEHPLGISFEFFPPNTEAGKEKLLGVRDALAARDPRFFSVTYGAGGSTQARTTQTVK
SVRESGINTAPHLSCIGSDKGAIRELLAQYREDDINSLVALRGDLPSGMGGGGIGELRYA
NELVEFIREETGNHFEIAVAAYPESHPQAQNFERDLENFARKVKAGANLAITQYFFNPDA
YFHFVERARKLGVEVPIIPGIMPITNYTKLARFSDACGADIPRWVRKQLEAYGDDSASIQ
AFGEEVVPRLCERLLDGGAPGLHFYTLNQAQASLKVLDNLRA
>A0A2N7TM20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas heilongjiangensis|TrEMBL
MSAQEHPLGISFEFFPPNTEAGRDKLMGVRDALAERRPRFFSVTYGAGGSTQERTLHTVQ
AVRQSGITTAPHLSCIGSEKARLRELLARYREAGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFEHDLTNFARKMKAGADFAVTQYFFSADAYF
HFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIGDF
GEEVVSRLCQRLLDGGAPGLHFYTLNQARPTLRVLDNICG
>A0A2Y9DMG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichechus manatus latirostris|TrEMBL
MDHLKARALPTRRCCPSLGIQAWEGGSGRFSVPPSISRNLAMVNEARGDGGPSPSSDGGS
SSGSESSKDSSRCSTPGLDPERHDRLWEKMRRRMESGDKWFSLEFFPPRTTEGAVNLISR
FDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCHQSREEIT
GHLHKAKRLGLKNILALRGDPIGKQWEEEEEGFSCALDLVKHIRSEFGDYFDICVAGYPK
GHPEAVSFEADLKYLKEKVSAGADFIITQLFFEADTFFRFVKACTEIGITCPILPGIFPI
QGYHSLRQLVKLSKLEVPQTIKDVIEPIKDNDAAIRSYGIELAVSLCRDLLASGLVPGLH
FYTLNREVATTEVLKRLGLWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFAHYL
SGEPNRNGCKVTCLPWNDEPLAAETNLMKEELLRVNRQGILTINSQPNINGKPSSDPIVG
WGPSGGYVFQKAYLEFFTSRETVEALLQVLKRYELRVNYHIVDVKGENITNAPDLRPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLV
NLVDNEFPLDNCLWQVVEDTFELLNRPAPE
>Q1YMD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantimonas manganoxydans (strain ATCC BAA-1229 / DSM 21871 / SI85-9A1)|TrEMBL
MKPIGYDLHAGRTAMPASIEIAPRQALESRDLPGLFPPGTKTYLCDVGVDAVKDFVRAVR
RVRDLGYEPVPHIPARRMRSRAELRDRVQAYAEEGGASDVLVVGGGLTRPAGPYSSTMEV
LSTGILDRHGFRDIGVAGHPEGTPDFSAATAAEALRLKRDFARRSDARLRIVTQFGFDAA
VYLQWAESVRAAGIDLPIHLGVAGPAKIATLIRFAALCGIGNSVSVLKKRPSALTALATS
HSPESVAGPIERHWAETPDTRVRQLHVFPFGGLAASAQWLYGRGSWMDATAIQTVAGTRQ
HA
>A0A7S2W9Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eucampia antarctica|TrEMBL
MTEGSISNGNSNGHDNGSASQADPRIVDLIKSANGEMFTSLEYFPPRTEAGVENLYNRMD
RMKENLSPLFTDVTWGAGGSTADLSMRLSLRARETGHVANLHLTCTNMEKDGDPIKGVHD
ALRAAHDGGIRNIVALRGDPPHGQDEWKASEGGFTCALDLVKYITKHYGKSFGIAVAGYP
EGHPNAISEVESLNDLSESEKKRCSNFDGKLYVCKDEDYKKEMDYLKEKIDAGSDLIMTQ
MFFDVEIFIQFVKDCRAFGITCPIIPGLMCINAYPGFKKMAQFCKTRVPKALEETMESLK
DDAAAVKSFGVEYGAEVCQALIDFGVDGLHFYTLNLEKVVYGITDKLGITNGLIEKSNEN
DASSMVAVGSAWARVGDIVKCTYGTGMVTEIRTDGVTVVEMTKWVLAYGQKPRAYLQSGQ
FKKLFV
>A0A1X7FIT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. URMO17WK12:I5|TrEMBL
MSLLKAALREKQFVCVMEFVPKPSAERFAAMEAIMARGQLCGWPMTVAIGDRVGSPLDMS
PLDALASFSTPLPALPHFSGKDRERHHLLAQLQRMDAAGHDQLLLLTGDRLPGHQPGERP
VRYLESVAALLTARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DASKHQEAIHWMQRQASPKPMLACLMGLTHGRATMLEHVAGVTVSPSMCDMLEAESKVSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGIHELKQLLALEERLHHWQAQIHSLEHWAPA
WADSWQMPGLPIVAFHPPQGNWRQGESTVSASSKEKVRYHLLHTAHSLLFSRANWLSKAF
GWAVRQPLWATKRGARVLHGLERAVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFEAQSP
RRINPQPAPRTQPES
>A0A7C3QTX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospirillum ferriphilum|TrEMBL
MNFRDALNAREFLVTAECSPPKGTNISGILDRLAPLRDRVHGMNITDNQTGVMRMCPMAM
GLHLKNIGIDPIVQITLRDRNRLAIQSDLLGMSSLGLSQVLCLTGDPPKLGDHPDAKPVF
DIPTQELIRAITLLNGGTDLSGKDLNGKTDILPGAACSPEGDLETESRKFEEKFDAGARF
FQTQAVFSPERMEQFMGFAAPFSVPVIAGIILLKSAKMARYLNDHVPGITVPQSLIDRLE
KSPPGQAIETGIDIAAETIRSIRPMVHGVHIMTVGAEETIPRILDRAFS
>A0A258S567|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium 28-57-27|TrEMBL
MNTSLLISCEFFPPKTDEGARKLRDTWQTLKDIDPEYFSVTYGAGGSTQERSFATVSEIQ
RDSGIPAAPHLSCIGSTREHIRAILDSYKAQGIRHIVALRGDLPSGMRDPGELRHANELV
EFIRAETGDWFHIEVAAYPEFHPQAASAQADLDAFQRKVEAGADSAITQYFYNVDSYLRF
MNDCLDRGIHIPIVPGIMPITNFTQLARFSDACGAEIPRWLRKRLETFGDDLDGLRSFGL
DVVGELCQQLIEAGAPGLHFYSMNQVEPTLHLWCGLNLRADMEL
>A0A1Y1BHJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia stabilis|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTDLCRRLVDAGVPGLHFYTLNAATATRTICERLAM
>A0A094X343|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospirillum ferriphilum|TrEMBL
MTFREALNAREFLVTAECSPPKGTRIDGLLDRLTPLKNRIHGINVTDNQTGVMRMCPMAM
GLHLKGIGLDPIIQITLRDRNRLAIQSDLLGMSSLGLSQVLCLTGDPPKLGDHPEAKPVF
DIPTQELIRAITLLNGGTDLSGKDLNGKTDILPGAACSPEGDQEAEFRKFEEKFDAGARF
FQTQAVFSAEKMEEFMRFASPFSVPVIAGIILLKSAKMARYLNDHVPGITVPAPLIERLD
KCPPGQTLESGIAIAAETIRAIRPLVHGVHIMTVGAEETIPRILDQAFG
>A0A4R3I1M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paucimonas lemoignei|TrEMBL
MTNPTSVQQNFSIEFFPPRTPEGVEKLRAVRAQLAALKPAYFSVTFGAGGSTQAGTRDTV
LEIRKEGHEAAPHLSCIGRSRDELRAILKEYREHGIRRVVALRGDLPSGYGAVGHEAGEF
HHANELIEFIRAETGDWFHIETAAYPEMHPQAKSPQDDLQNFVRKVKAGANSAITQYFYN
ADAYFRFVDEVRAAGVEVPVVAGIMPITNYTQLTRFSDMCGAEIPRWIRLKLASFGDDTE
SIRAFGLDVVTAMCERLLAGGAPGLHFYTLNQAAATTAIWQRLVR
>A0A1G1B3E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp. RIFCSPLOWO2_02_FULL_45_14|TrEMBL
MKTPPNKFELSFEFFPPKTTEGMDKLRETRSQLAKFNPEFFSVTFGAGGSTRDRTMDTVL
EIQHEGFQAAPHISCISSSKAEIRDLLLAYQAQGIKRLVALRGDIPSGEVSAGDFRYASE
LVQFIRAETGNHFHIEVAAYPEFHPEARTPAADLQNLKRKVDAGANSAITQYFYNADAYF
RFVEQCDALGITIPIVPGIMPIYNITQLARFSSICGAEIPRWLKMRLEEYGDDMTSLRAF
GVDVVSELCDTLLAWGAPSLHFYTLNQAGTISNIIHNLSE
>A0A2P5KDD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycetohabitans endofungorum|TrEMBL
MSLPEISFEFFPPKTAEGVDKLRATRAQLAPLKPKFMSVTFGAGGSTQQGTLDTVLEMAG
EGFEAAPHLSCIGASKESLRGVLAQYRRHGIRHIVALRGDLPSGMGEVGELRYACDLVAF
VRAEHGDWFHIEVAAYPEYHPQARSPRADLENFARKVKAGANSAITQYFYNADAYFRFVD
DVRKLGVDTPIVPGIMPITNYAQLMRFSEMCGAEVPKWIARRLESFGDDRDAIRAFGLDV
VTAMCERLVVNGAPGLHFYTLNGAVASKAICERLRA
>A0A5P3VHJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus oxalaticus|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVKAGADSAITQYFYNADAYFRFVD
DVRAQGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A094AMS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-3775|TrEMBL
MHVKDMVSQGEQAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHA
QLTCEMVSVAQSVYGLETCMHLTCTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEK
WVATDEGFQYARDLVRYIRKTYGPHFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATF
IVTQMFYDVPNFLEWVRKVRAKGITIPIIPGIMPISTYSSFLRRCNHMNAKIPPGWIEAM
EPVKNDDAAVREIGRGLVADMCRAILKSGINHLHFYTMNLAHATRSVLEELDMLPSEERP
LKQALPWRQSLGLGRRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGEPKSVKDIANVFLRYLNADIESLPWSEAPISNEADVIKNQLVQ
LNERGLLTINSQPAVDGVKSSHPVYGWGPSNGYVYQKAYLELLVAPELIDELLDRIAKDP
EVTYYAVTKSGTLRSNAPGDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHDASSPSRNVIQRVMETFYLVNIVHNDFHQRDALFSLFEGLAVPNIDQSAEGEVAPT
AVPTPAATTVPATNGDKVEDAPPAIVSNVLPVA
>A0A2G5GNG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gaetbulibacter sp. 4G1|TrEMBL
MKVTDHIKKAKGNTLFSFEIIPPKKGKNIQELYNNIDPLMEFNPPFIDVTTSREEFVYIE
KEGLFDRKITRMRPGTLGICAAIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKGEQYFKATKGGHSYATQLVKQIQNLNSGKYLHGTLDVDDKADFCIGVAGYP
EKHLESPSMQSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVDAAKKEGIDVPIIPGIKP
IAVKRHLQLLPQVFKIDLPETLISEVEKCSDNKQVRQVGVEWCIQQSKELLDAGVPVLHY
YSMGKSDNIKSIASQLF
>A0A1H0RKA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus singaporensis|TrEMBL
MARNFNDDISTPEKFVITLELVPGRESSGRTIDTINAISQEAYQDKRISAVSITDNPGGN
PALSPDAIGRNILNCGMDVIVHFTCRDTNRMGMESRALQLAHMGMKNILALTGDYSGKGF
GGRGTPVFDFDSVILTSMLNDLNRRLIKTGHSSVFVTGCAVSPFKYTEAETWVQYKKLER
KFEAGASFTITQLGYDIDKYEELLLYKNDRQLDYPALASLYLLDKRSARPMHAGRVPGVH
VTKKLFDRVMEEWQDPQEGKKQAIERTARLGVVLKGIGYKGIHLGGIHDSFDTVGRILDR
MEEIEHNWQDYREQFTEDEPNRFYLYKKTAATKSIPSRDAIKVKLSENCHYLFLRTAHDL
FFDKNASFAPVYRKISSSLDKNKASWVLKRFLEDPFKKMMLSCQSCGDCGIQHVGFLCPE
SGCPKHTRNGACGGSNNGYCEVNPDKLCVWVRAYRRMRKHGEAEKLACELVPPRLWELKD
TSSWINFHLDRDHQGGQQPAAKKPAKQSEAKG
>A0A8J5SJJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zizania palustris|TrEMBL
MMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQNKFVQVAGGFACALDLVQHI
RSKYGDYFGITVAGYPEAHPDAIEGVEGATLEAYSNDLAYLKRKVDAGADLIITQLFYDT
DIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALDPIKDNEEA
VRAYGIHLGTEMCKKILASGIKILHLYTLNMEKSALGILMNLGLIEESKVSRSLPWRPPT
NVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNPSYGALTDYQFTRPRGHGK
KLQEEWAVPLKSVEDISERFMNFCQGKLTSSPWSELDGLQAETKIIDDQLVEINLKGFLT
INSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSKEKLDQLIEKSKAFPSLTYIAVN
KDGESSSNVPTNAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGWACLFPDG
DSSREILDKVQKSYFLVSLVDNDYINGDLFSAFKEIS
>A0A6G9JQS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MSFLKSTYYQDIMNQKLNNLNKKIQCSFEFFPAKNINLEGKLFSSAIKLSELKPFFFSVT
YGANSGERKKTYEMVKKIHQKTGVITAPHLTCVDSTYTELEQIAKFYWENGIRSIFALRG
DSNNVHHQHTMYAYDLVVLLKKIADFDISVAAYPETHPEAKNAKSDILNLKKKVNAGANR
VITQFFFNTDIYLRFRDNCLKNNINVEIIPGILPIYNFEQLKRFAKMTNVSIPSWMFEIF
RGLSNDLATQRIIGSSIVIDMIKNLSIAGVKNFHFYTLNQSDIVYSICRLFGF
>A0A654CMX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. 8AQ|TrEMBL
MSQFLKKLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVERIHRSYIEAGADVIQT
NTYGANFEKLKVFGLEHKVKEIHKAAVQIAKKAANNDTFILGTVGGFRGVKQDELSLSTI
QYHTENQIDTLVDEGVDALLFETYYDLEELTGIIVSTKRKYDIPIVAQLTASNTNYLVDG
TPINDALKHLVECGADIVGLNCHHGPHHMQRSFSHIELPNNAFLSCYPNASLLDIKNSEF
KYSDNAQYFGDIAQELIHEGVRLIGGCCGTTPEHINYIKTSVSNLKPVNHKNVIPIHKKV
NREKDISFKQSLTSKVKQGPTVIVELDTPKHLDTEQFFNNIGKLDDADIDAVTLADNSLA
TVRVSNIAAASIIKQRFNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEATKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITTHKEAIL
>A0A813DIY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polarella glacialis|TrEMBL
MTEDALTACRKMGVRNIVALRGDPPRGAEKWTATEGGFNSALDLVKFIREKHGDYFSLSV
AGYPEGHPDNIDVIAGGVAALSPSEARRCRVVKDENGKEVVTVCPDAKFVKEMIYMKEKV
DAGAEFIITQMFLDATVYLDYVVECRKYGIMVPVVPGIMCLNNIGGLVRMTELCKTRVPV
GMMERAEKANTSDDAFKAFGVVEGAAMCKQLLEGGAPGLHFYTLNLEKVVIGTLVELKLI
TAQQAAEFQSGDADAKSMVSAQGISTGTVAGRPALSGNRSLKEADPTMYQLVLDEKARQI
SCIELIASENFTSRAVMECLGSALTNKYSEGQPGARYYGGNEVIDKVENLCKARALKAFG
LDDKEWGVNVQPYSGSPANFAVYTALLQPHARVMGLDLPSGGHLTHGYYTAKKKISATSI
YFESLPYKVHPVTGLIDFDELRKSALVFRPAMILCGASAYPRIVDFAKFREIADEVGAYL
MADIAHISGLVATGEHPPPFQFCDVVTTTTHKSLRGPRAGMIFFKYSDKVPDMKERIDMA
VFPALQGGPHNHQIGALAAQLLEVDTQAFKDYSKAVKVNANALADALKAKGHKLASDGTD
NHLVLLDLRPLGLTGSKMEKICEAACISLNRNAVHGDVSALSPGGVRIGSPSMTTRGATK
EDFVQIAGFLDRCVRIALKLQTTHGKKLKDFEAAVPSDPEVMALKKEVNEWASKFGYPGL
>A0A231HHE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp. T2|TrEMBL
MKQALLDGQFICVLEIIPRQSSSSTSAHKKILRRGHLAGWPLFLSFSDRVGLHCDLSPLE
GAAALGDPSSSLLHFSGKDRERIDLLLYLDEMKARGLSQLLLLSGDRLPGHHPEQSPVHY
LESVPALQIARTHCPDWLLGAALNPFKYLEEEGCAQYLKAQKKILAGADFLTLQLGFDAA
KHLEAQTWMSTQADTKPMLACVMQLTAKRATGLNHVPGIVITKSMRAVLDRELNVSLSYA
DTRSFERLGLQIVGLQLMGYAGVYVSGVHALDELIALEQVIGRYRDRISSVADWMELWLE
SWEIPGAPKVCFTPESASWEIGQSDVKASHLEQLRYTLLSKVHHLFFSRYGWLSKAFGWN
VTRPFWKNSTAASALHALERAIKRPLVGCDTCGNCRLHDTFYVCPETCPKGLANGPCGGT
HLNRCEFGDRECIHSVKYRIAKSVNQLPLLRQSVTPCIDARDRRQSSWPKWFKQDPDR
>A0A7J9NEF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium schwendimanii|TrEMBL
MKVIEKIQSLQEGEVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIISVETMMHLTCTNMPVEKIDDALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVVRVKEDVRPIFWSNRPKSYITRTIGWDQFPHGRWGDSRNPS
YGALTDHQFMRPRARDKKLQEEWATPLKSIDDIKEKFKSYCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGTDVNAVTWGVFPAKEIIQPTVVDPASFMVWKDE
AFEIWSRAWAALYPEGDPSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>A4Y316|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAADLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPNWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A1I1LS57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces aidingensis|TrEMBL
MALGLPSVRTDHARTVRELLAGGERSYSFEFTAPRTAKGERALWEAIRQVEAVGPTFVSV
TYGAGGYSREGTVRATERLADDTTLTPVAHLTAVNHSKAELRNIIGRYADVGIRNMLAVR
GDPPGDPMGEWVPHPQGVTYAAELVELIKESGDFCVGVAAFPEMHPRSTDWETDIRHFVA
KCRAGADYAITQMFFAADDYLRLRDRVAAAGCDVPIIPEIMPVTSVRQIERFAQLSNATF
PPELERRILAVKDDPAAVRSIGIDYATELCARLMQEDIPGLHFITLNRSMATLDIYRNLG
LDRQT
>A0A1I0BAM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus poikilotrophus|TrEMBL
MQGGSRGGRSVSSLSMSRTVRELLDEGRPTWSFEFFPPKTPEGATQLWTALRDLERLQPS
FVSVTYGAGGSTREGTVSVTERIATETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNL
LALRGDPPGADPQAEWVAHPEGLQYAAELVELIRSMGDFSVGVAAFPERHPRSPDFDTDV
AMFVRKCRAGADFAITQMFFRAEDYLRMRDRVAATGCEVPIIAGVMPVTNARQITRIVQL
SGQAFPEQLAARFAELDGDTPEAKAAVRAYGVEVATELCRTLLAEGVPGIHFITMNRSTA
TREVHANLAAVGSPH
>A0A3D8UQX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kangiella sp. HD9-110m-PIT-SAG07|TrEMBL
MSSPLITPHKSNPTYEEARIAELLNQQIADLNGKVNVSFEFFPPKTYEMQQTLWSSIKKL
EPLQPNFVSVTYGAGASTRSRTHDVITKIIRETELTAVPHLTCIGSTEAEIERIAEDYWS
KGVRHIVALRGDLGDGAEQGDFKYATDLVIKLKQLHDFEISVAAYPEIHPEAKTAKADLE
NLQRKVDVGASRAISQFFFSAEKFLRFRDQCQTQDLQIDLTPGILPVTNFAQLQKFAKFT
QVDIPRWMYKVYEGLQNDPETSRLIASHIAIEQVKLLVKEGVSDFHFYTLNRAELTYAIC
HSLGKRGLTSAA
>A0A2H5Z7M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR28|TrEMBL
MTDSPSSLVSTEAQIDTRFLCSLLRELRIEVLPNVDLSKVSSIVPRDATLTVTSSPAHGV
EGTLQTALALRREGYRVVPHLAARALRDRSQLAQLWHQYTSAGIDEVFVVGGDQERPAGE
FPNSLALLQTLVELEPPPTRIGITAYPEGHPHIPNDVLEADLLAKQAYAHYAITQLVFDP
DALLNWLVRSRARGFTLPVYLCLPGTLRLDRLIRIGMSLGLGTSLRYLEKQRGLVGRLLT
GGLRYDPGDLLDGLARRPAAAHAGIVGVHWSSFNSVDSVVHWVLARRESLGCGQEGATA
>A0A6G3U297|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7958|TrEMBL
MALGTASTRTDRARTVRDMLAGGKTTYSFEFSAPKTPKGQRNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVHETEQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNAVF
PDTLKERILTAKDDPATVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A7X8YHE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio agarilyticus|TrEMBL
MGYSHASHIDALNQSIAELSNDINVSFEFFPPSNEKMEQTLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKSATGLVAAPHLTCIDASRAELIAIAEDYWQNGIKNIVALRGD
IPPHGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVAAGIEVEIVPGILPVSNFKQASRFAAQNQVKVPGWMSKQFA
GLDEDPVTRQLVGASHAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPEVGVLS
>A0A7X8RST1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olsenella sp. KGMB02461|TrEMBL
MAIETVSQIFATQKLPISFEIFPPKGDLSQEEAQQVASKLAPLDPAFISVTYSAGGSGNS
SRTLEVAQLIQRDFDVSTVAHLTCQGLTRQSLAKKSARLKEAGIKNVLALRGDPNPEAAP
GDFEYASDMIPQLVEDGFCVGAAAYPEGHISCLDPDIDVAYLRGKQDAGASFLVTQLFFD
NQLAYRFRERCHKAGITVPITFGVMPFLSKSQVSRMIFMCGVSLPSAVVKLLARYEDDPA
SLRAAGVEYACAQLQDLALHGVDGLHIYTMNRPQVAAAAVAAIREAL
>A0A3E0IQV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus felis|TrEMBL
MSRLLETLKHNVLVADGAMGTILYSEGLDTCPESYNLTHPEKVERIHKSYVDAGANVIQT
NTYGANFEKLKPFGLEHKVKAIHEAAVAIAKRAANEDTFVLGTVGGFRGVQQGELSLSAI
QYHTEIQIDTLVSSGVDGLLFETYYDLKELLGAVTLARKKYDIPIIAQLTASNTNYLIDG
TLINEALSQVIEAGANIVGLNCHHGPHHMKNTFSHIEIPNHAYLSCYPNASLLDIDHNHF
KYSENAEYFGNIAEQLIEEGVRLIGGCCGTTPEHIRKIKDAVTGLKPITDKKVIPIHKKR
ERTKKEPHSLNLAERAKKQPTIIVELDTPKHLDTKRFFENVKALDAAKIDAVTLADNSLA
TVRVSNIAAASLIKQRFDIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKI
GHLPGATNVYDVNSKGLTELALKFNEGINTDGDALKAETNFNIAGGFDPHVRNINAAVRK
METKIESGMHYFITQPVFTKEKIIEIYEATKHLDVPIFIGVMPITSYKNAQFLHNEVPGI
KMSDDVLAQFKAVAG
>A0A7Y3Y8K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio europaeus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASRKELIQIADDYWANGIQSIVALRGD
IPPGGGKPEMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPTA
>A0A5S3T971|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas galatheae|TrEMBL
MALTLQEKIIDPNQGVYLIGTTPPKIGTDPEQLKSIAAKLLGRLHEIEYDGVIIYDIQDE
SSRTQVPRPFPFKHTVDPCEYSQLIRELSHLDVITYKSVAQRDSEAFGNWLSSTKQQYGL
NNLVLVGSPSSQGDIKLPLSEAYDVLKHHQDDFFLGGVTIAERHASKRNEHERLIDKTEQ
GCQFFVSQAVYDAQATIDLITSYARTCKQQGQTPKRIILTFTPCGGEKTLQFMEWLGISV
PEATKWRMLDSENTLSESIRICRENLDQILKSCSHLDISLGLNIESLTNRKEEIDASINL
YRLLKATMELCLAEKQIA
>A0A212PGB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp. DSM 9736|TrEMBL
MTSRLQQQLDAGRFVITAEVCPPKGCDCTDFLAHARALQQHVDAFNVTDNQGANMRISPV
AAAALLVGEGIEPIFQITCRDRNRMALQSELLGAAALGVTNVLALTGDHISFGDHRDARP
VFDLDSVQLLQTIAELNAGRDIAGNKLQGAPSFFAGAAAAPEAEPFPLTLMKIRKKVETG
ARFFQTQAVFEPEKLRLFHEAVAPLQVKVIAGILLLKSAGMARYVTRNIPGLKVPDHIVD
ELEKAADPLEAGVEIARRTAAAARPWCDGLHIMAMGREDLIPRIIEAVR
>A0A2Y9C037|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Georgenia satyanarayanai|TrEMBL
MSTASLVTVPHGRPTVSFELYPPRTPAREASAWETVERLAASGPDFFSVTYGASGSTRDA
SRTLVRRILTETSVAPIAHLTSVGSTRAELERFVEELVDDGVRDFLALRGDPPAGQREWV
PQPDGVNTTAELVTLIRSVERARFGTTGELSVAVAAYPAGASHTRTQDVVALLDKQAAGA
DFAITQVFYDPAAYVDLVEEARSAGVALPFVAGIIPMTDPRRLTRLAQLTGVPVPEALLE
RLASAADDEERHRIGIDATAALVEEVVSAGAPGLHLFTFNQHRPALDVVERLRRPLSTTS
TRTTS
>A0A177MYI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas lenta|TrEMBL
MNISFEIVPRSLDAFEKQYAFLQSLDSGINIINVPDIQRFDIRSWELATRIDRNKYRFIP
HFRAIDFKIESGELYRVIEQYQLDDVLLVTGDPPEGLKRSYCNTDVVDLIRAVRRRFPAL
NIYAGFDPHRQGLQHECHYIQRKADAGANGFFSQPFYDHRLVELFAEHMDGLETYIGISP
VVTLASQNYWEVKNHVKFPKHFRPDYDWNIEFANRLIDSAAESGWHVYFMPIKVELKQYF
ERIGLAKPVPARP
>A0A351NJR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRNELRAIAQDYWNNGIRHIVALRGD
LPANGGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A150HHS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium laevaniformans|TrEMBL
MMSHEPRVDAPAVAGTASPRVPFSFEIYPPRTPEQLPALYETIRVLAAAGPRFISVTFGA
GGSTTDRSLTVLTHILRETTVPPVAHVTCVGSSYAEATTVIRDFLDAGITRFLALRGDPP
AGVGEDDIVFGDLESAAQLVQLIGRVQAERSPYREREIPGLPGAVQVTDGDRVEIAVAAF
PNGHPRSRHRYEDIDALLAKQAAGATSALTQLFFHADEYLDFVERARAAGVVIPIVPGIM
PITSPGRLRRVLELTGDARPDSLAAALESAPDAAAQRAVGLAHAADLARSVVAGGADGIH
LYAFNNHDTVLGVLRAAELIPEASP
>A0A373VN17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. AF19-10LB|TrEMBL
MASVKLTELMKERQLLSFELFPPKTDKGMENLPGTIEHLCQFEPEYISVTYGAGGGNVGA
NREVCQMVKKAGTVPVTHFTVIKNTKEGIRDQLETYLREGVDHILALRGDFPRGEHSTGG
DFNYATDLVKFIRREFGDKFEIAVAGSPEGHIACRSLDADVSVLKMKQDNGADYIMTQLC
WDMEQFARWQDKIRKAGVTMPIDVGIMPILDQAATISMALSRNGCVMDRELSRLISKYWI
FPNPFDKAPFDDNLEQKKEDFKKAGIEYTIRQIDKYRALGVEGIHLYALNKWKDVSEIIN
ASGMRTLI
>A0A1H3I099|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter psychrophilus|TrEMBL
MKVIDHLTRAEGKTLFSFEVLPPKKGENIQTLFSNIEPLLEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFTKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFVPEPDGHSYACDLIGQVSDLNKGAYLDEEQDDTWATDFCIGTAGY
PEKHFEAPNYGADLRYLKHKVDRGAEYIVTQMFFDNEQFFAFERRCREAGILVPIIPGLK
PLTTKSQLTMLPRTFYLNLPEALADAVHLAPDNAAARQIGLEWCINQSRELMAHGVPCLH
YYSMGKSDSIRQVAAALF
>A0A1A3PFE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. 1245111.1|TrEMBL
MVDQLCPKRMQYGPCGGVKHDGQCEMRSGPCAFADVVPWQGAAVAMSPVAAPLILTDFSC
TPFDAADIAATAVTLASSCDAVLVGEHQNRPDFPPTLMSQLILDEGVTPWITLSCRDRNR
VVLEQELRGLRFTGATTVFCVTGDGRGYDVRPDVTQTFDLDGPRLVALAASLDMVAAVPE
TPTAPPTHARAARLIEKQRAGASLAVLNHVSSASALSAFMHDARSAGLRMPVLAAVAVFT
DVVSAAVLQGLPGLELEPEVVESVVNAADPVEAGIMAAVAEARALLAINGIDGVNLSGLA
SAAGTRRGAEIKAEVGARIRAELT
>A0A1Y1QWK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiothrix lacustris|TrEMBL
MTDDHHHDHQPDDLVFSFEFFPPKTDKGAENLREVRSQLATLEPRFFSVTYGAGGSTQAN
TLNTVLEIQRDSGIEAAPHLSCVGSSADQIREILDTYRSNGIKHIVALRGDLPSGSRDLG
QFRYANELVEFIRKETGDHFNIEVAAYPEMHPQAPNLTADIDNFVRKVKAGANSAITQYF
FNTDAYWHFVDECVKKGVDIPIVPGIMPITNYAQLARFSDMCGAEIPRWLRKQLETYADD
TDAIAQFGEEFISLLCENLLETGAPGLHFYTMNRVEPTMSIWKNIGLAD
>A0A3C2BF60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium|TrEMBL
MSFFHANQREALNQSLAEVAGRINVSFEFFPPRTSEMEQTLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWENGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFS
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A510JM16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia shahii|TrEMBL
MRIKDLFEKKKHLISFEIFPPNKNFSVEKLKDVTDELVQYKPDFISVTYGAGGKTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEINDYLQEAKKCNIKNILALRGDVPQGETEDIYN
KGDYKYASELISDLRKNSEFNDLSIGGAFYPETHYENNDLVDLFHLKNKVEAGTDFLASQ
MFFDNDVFIKFKEQAEKLDIKVPLIAGIMPVTNAKQIKRIIELSKCSVPEKLDKLLEKYG
DNPESMKKAGIMYASEQIIELLAYGIRGIHIYTMNKPEIAKEIMKNIEFAR
>A0A385Q143|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoanaerobaculum umeaense|TrEMBL
MENIRDYLKNNILLFDGAMGTYYDELTDDGIGCELANIKNPELIRGIHNEYIKAGAKAII
TNTFSTGIDAFFGDRELQKEVINAGIDIALEVAKDRAYVFADMGVLSVDSNSEAFEEYKI
LADIFIEKGINNFLFETRNSTIGLKAIGEYIKERSPESFIIASFAVMPDGYSSEGYYYKS
MFKEICESGFFDAVGLNCVSGANHMAKLLKDVDTDGLYLIAMPNAGYPIVRDNKIHYGSL
ANYFAAQIEDILDMGVNVVGGCCGTTPKHIELLKKSMSGMLIKPRKSVKKEKNVFQNVRL
NRFEQKLLSGEKPIAVELDSPIDTNVSKFMENAGKLKTAGADIVTIADNPIARARMDSCL
LACKVRNELDLDVLPHMTCRDRNVNAAKGLLLGASAMGVDNVLVITGDPIPNAQRDEIRS
VFEFNSVKFANFIKSLNDEVFESPMNICGALNVNAKNFSAELRKAKRKQENGVKVLFTQP
VLTQRAIDNLKEARENLDIKIMGGIIPIVSERNARYMQSEVNGIYITDDIVEKYIGKERE
EAEEIALSMSKEIANEIYDLVDGYYLITVLNRVSLMERLIKTVKEVCENR
>A0A7W6H4T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas pseudogalii|TrEMBL
MAQRKSQRSPIRASFEFFPPKTPAMEATLWTAIQRLAPLRPDFVSVTYGAGGSTRERTHH
TVKRLLAETELKPAAHLTCVDASRAEVDDVVRQYSTTGVRHFVALRGDGQGGAGAAYEAH
PEGYRNAVDLTAGIKRIDPDIEVSVSAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNDLYERFVERVRRAGIYVPIVPGIVPIHDFTKIARFSAATGASIPAWLAERFQGLES
DPHTHSHVAAAVCAEQVLDLAERGISDFHFYTMNRADLVYSICHILGLRGEAPAEPVSEA
AAA
>A0A7W2LQT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas juntendi|TrEMBL
MSLLKTALREHHFVCVMEFVPKASAERFAAMQAIMDRAQLCGWPMTVAIGDRVGSPLDMS
PLDALASFDRPVPALPHFSGKDRERHHLLAQLQRMEAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPLWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQAAPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMREMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGIHDLKQLLALEARLAYWQTHVHTLEQWAPA
WQASWQMPGLPAVTFHPPQANWRQGESRVDASFKEKARYHLMHGMHGLLFSRRNSLSKAF
GWAVRQPLWTTRLGAQVLHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGSALNRCEFGDRECIHSIKYRTAKAVGQTAVLRERLIPCIEEQTRHRSSWPQWFAPPSP
RRVSPQPAPRTQPES
>A0A0P0R611|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia caribensis MBA4|TrEMBL
MNPIELSFEFFPPKTQEGLDKLRATRAELLPLKPKFVSVTFGAGGSTQQGTLDTVLDMAK
DGLEAAPHLSCIGSSRESLRAILNEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFRIEVAGYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VADLCRRLVEAKVPGLHFYTLNGAAATKAICERLGA
>A0A0K9I9A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocarbo indianensis|TrEMBL
MKAGSNLEKVLEAGHFAVTGELGPPRGNNVEEVRHKAAHLKGIVESVNITDNQTAVVRMS
SWAACKILLDEGLEPNFQMTVRDRNRIGLQSDLLGATALGIKNVLCLSGDHQRFGDHPEG
KNVFDLDSMQWIALCKKMRDEKKFLNDKELDGAPEIFIGAASNPFGDPFSFRPMRLAKKV
AAGTDFIQTQCIYNMDKFREFMKRVVDLGLHEKCYILGGVTPMKSVGMAKYMAKFVPGMD
VPEEIVKRLTDAGKKNAAEEGIKIAIESIHQLKEMEGVAGVHVMAIEWEHRAKEIIEGAG
LLPRPKVD
>A0A6B3E5T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8499|TrEMBL
MALGTASTRTDRARTVRDMLATGKSTFSFEFWAPKTEKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVTAAGCETPVIPEVMPVTSVKMLERLPQLSNAVI
PDALKERILAAKDDPTAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A0M2SVX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesobacillus campisalis|TrEMBL
MSFLSKLQNGLLIGDGAMGTLLHSFGTDTCFEELNLSHGEDISRIHSAYIEAGADLIQTN
TYAANYLKLQRYGLEEQVKEINSAGVKLARQAAGSEAYVLGTIGGSRGLRPSMLPMEEIK
RSFREQLYCLLLEGVDGILLETYYDLDELETALAIARKETNLPIIAQLTLPELGMTQNRV
PVNEAFHQLEELGADLVGLNCRLGPHHMIKSLEAAEIPKKAYLSAYPNAGLPSYTDGRFQ
FETNADYFRQCARDFREQGVRLLGGCCGTTPEHIKAFATELKGLSPVSEKTVVRKTEKIL
VEPSSLKRSELPLQEIVKKRPSVIVELDPPRKLDTTRFFDGAKALKAAGIDAVTLADNSL
ASPRISNSALGHMVKEHIGLRPLVHLTCRDRNIIGLQSHLMGLHTLGLHDILAITGDPAK
VGDFPGASSVFDVSSFELIEMIKQFNQGLSPSGKDLGQKGAFSIAAAFNPNVRSLEKAVA
RMEKKIKCGADYFITQPVYSEKLLLEVYEQTKHLDAPVYIGLMPLTGSRNAEFLHNEVPG
IKISQDILDSLAAIKHDPVQSKREGIAITKSLIEAAAELFNGIYLITPFMNYEMTVELAH
FAHEYSEGLSRRKLHAKSFIN
>A0A1V6BB03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin145|TrEMBL
MSIIKPARRWQPAFYPFKKEKFSARLLGRIELAVKGPVFGCRMCGNCLLQETAFICPMEC
PKGMRNGPCGGITPEKNCYVDESRKCVWYAIYERSRKMGRQKMLLEVLPPLDWYKVGTET
WGVVVRQVRKTGIWTFIRSLFLKDKIKKSEVWDSVFKTIRQPAWWMGDSEYHKPAYEEPA
SLLEKKLRNGEFVIATEVSPPLGANPAKIIREIELVRPWVTAVNFTDASSASPKMSGIAC
CKVANDLNCEAVFQIAARDTTRTGLQSAVIGSGQMGVRNILCVTGDNPRVGPSPASDMNF
VDVDSVQMLWILRRMRDEGIYLDGRKIKYPPKFFLGAATTPFASDPELQAIRDQKKINAG
AQFFQTNLIFEPDRLDQWLEQLDKRDLLDKVYILAGISPLKSYKIARYLHDKVPGVFLPK
DILTRMEKAGDGASEEGFQIALELIDSIKSKKGIHGIHLMTMGWEEIVGRLVAESGILQQ
>A0A1G4Y924|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klenkia marina|TrEMBL
MTGTVRDLLDQARPTWSFEFFPPKNEAGQEQLWTALRELERLAPSFVSVTYGAGGSTREG
TLAVTERIATDTTMLPLAHLTAVDHSVTELRNVISRLAAAGVRNIMALRGDPPGADPQAD
WTAHPQGLRYAAELVELVKSIGDFGVGVAAFPESHPRSSDAETDADMFVAKCRAGADFAI
TQMFFRVEDYLGLRDRVAARGCDVPVLAGVMPVTSTKQIARIVQLSGQAFPAELAERFAA
VDGETPEAKRAQRELGVDVATEMCATLLAEGVPGIHFITMNRSTATREVYSRLVPASASA
AS
>A0A7C2Y5Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesoaciditoga lauensis|TrEMBL
MKVIDLVKKQRILSIEVIPPDRGKDIDEIFSAIDEIMEFSPSFINVTRHAPEIDYLEFGD
RIIKVPKIKRPGTVGVSAAIKNRYNVDVVPHVLCLGMNKFEIEDMLIDLKYLEIENLFVI
RGELENRKEMASEKDGYNHADELVAQISKMNKGIYLYPVENPKSTNFCIGVAGYPEKHYE
ALNLEEDLKYLKKKIDAGADYVITQMFFDFEIYKNFVEKAREIGINVPIIPGIKPIVQFK
SMVKIPSTFFVTIPKEFASAMQEAKTPQEEFKTGTRYMSKLVDKLLNYGVPGIHIFTMGK
GKSTKALLEAVYK
>A0A3E3E779|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalicoccus pleomorphus|TrEMBL
MKVSEILTQDKVTLSFEVFPPKKIDDYSKVEAAAKKIASLHPDFMSITYGAGGGTSQYTV
DLARDLYQKYGTQVIAHLTCVSSTREHVLNMIQKCKDAGIENIMALRGDIPKDGRIAHDY
QYASQLIQDIKAQGDFCIGGACYPEGHIECEHKKEDILHLKEKVDAGCDFLTTQMFFDNN
IFYNFLYRIRESGIQVPVLAGIMPITNKKQLARSVQMSGTQVPERFKAIVDHFGDDPKAM
EQAGIVYASEQIIDLIANGIRHIHVYSMNKPDVAARIQANLSEMIK
>A0A496LKZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp|TrEMBL
MLKEKIRNGKSGILLYGIVPPKITSSQDELERLGTAWSQRLGECECDGIVIYDLQDESAR
TKDERTFPFVHTIDPARYYTQYLHTDKEAIIYRAVGKYDEAEFCEILRHAASGLGVFVGA
SSKNEECKLHLSHAYELKRLVAPHLCLGGICIPERHEKSRDEHLKIAEKTADGCEFFITQ
AVYNVQNAKDFIDDYAALECKKVPIIFTFTPCGSLKTLEFMKWLGISVPDFLQQRLQSSV
DILQSSTALCAEMFDFIYKYALAKGVSVGANVESVSTRRVEIEASLSLLKEIRKIILKHE
NLGFYVI
>A0A3D1ZTZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium|TrEMBL
MQFSFEFFPSRDNAGQLALDMAVQQLKQWQPAFASMTYGAGGTGQQASLAGTGRLLQQNL
ATAAHLTCVGASKAEVQAAAQQFVAQGVDHFVALRGDSPSGDYQPHADGFAYANDLVAGL
REWFAGTISVAAYPEVHPQAPSAAQDLHFLKAKLDAGADQIITQYCYDTDTLLRFAEQTQ
KAGIETPILMGIMPIHDIAAVQRFSARCGASVPQSIVDRFATFDQTKDITKLGIEIAYEQ
CQRLLDNGFDQFHFYTLNRSTLTAGVLNAVQASDQGLALTA
>A0A2N6E7L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MSQLAIELVPRNREVLERDMALVREHFPHVDTINIPDLLQFDLRSWDAGDIVSTQFPNVI
PHLRAIDFDLRCDWPFLETIRNTGCPALLAISGDPPQDMLHRTYRTPITGFIARLKQELP
GVKVYAGLDPYRSGIKEELDYVAAKLDAGADGLFTQPFFDLRFMEIWADLLPGIDVWWGI
APVLTEKSQAYWENKNNGFFPPDFKPTLDWNREFARRALEFTRGRDASAYIMPIRADIRK
YLEGIV
>A0A4U1CDI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter frigoris|TrEMBL
MKIVDHIKNANGKTLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFNKDETENALIDLQFLGIDN
VLALRGDARKSDSSFVPTPDGHAYASELVSQVSDMNNGRYLHDDIGELERTDFCIGVAGY
PEKHFESPNLDTDFKYLKLKVDLGAEFIVTQMFFDNQKYKAFVEKCRENGINVPIIPGLK
PITSSKQLVSLPKVFHLDIPVELSEAVQACKSEKDVKAIGIEWMINQCKELRDMGAPVLH
FYTMGNPEPTKKIAQAIF
>A0A149QYR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter potus|TrEMBL
MKRLLSGKLADHPSLCHSDMPVPVLSFEVVPPRTDAMERRLWQCIRRLAPLSPRFVSVTY
GAGGTMQARTQATVLRLKQETTLVPAAHLTCIGATCEEIDDIARTYWQAGVRHLVALRGD
APAGTAYTPRPGGYAYASDLVAGLRRIADFEISVAAYPETHPIALSPQADIDNLKRKFDA
GASRAITQYFFEASTYLRFLDRCLAAGIVAPIVPGIMPVSNYDQIARFSALCGVTVPAWV
THLFEGTAKNPELCRIAACIVAAEQVRTLQSHGINEFHFSTLNRPDLTCAIAHLLGVRPA
SETDS
>A0A5D8YUY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. BS3|TrEMBL
MKITQHIQNAKGKTLFSFELLPPVKGKCIDEIYDAIDPLMEFDPPFIDVTYHREDYIYKQ
HTSGLLEKVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARKADAGFIPTPGGHAYATDLLEQVVNMNKGLYLHEDHEAYKTNFCIGVAGYP
EKHFEAPNMKTDFSFLKKKVEMGAEFIVTQMFFDIQKYCDFVKLCRENDIHVPIIPGLKP
ITSSKQLISLPKIFHIDIPEELSEAVLACKSEKEVKEVGIEWMINQCKELVKVGAPVLHF
YTMSNPEPTRRIAKAVF
>D4DU99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria elongata subsp. glycolytica ATCC 29315|TrEMBL
MQTIGDILAEGTAAAPHLPCIGMTAAEIRELLDTYKEMGVRHIVALRGDIPSGMGAGTSG
LRYANELVELIKNEYGSHFHIEIAAYPEYHPQARSAEDDLNHFVRKAKAGADSAITQYFY
NADAYFRFLDDVRGRGVDIPIIPGIMPIASFSKLVRFSDTCGAEIPRWLRLKLQSYADDS
AAIKALALDVVTEMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>A0A291TYF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. CA23|TrEMBL
MGFHSARQVEALNQSLADLSGDIGVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKDPA
>A0A1W9T3F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_123|TrEMBL
MNLKTPSKLEKIMAAGHVAVTSEVGPPRGSDPEVITAKANLIKDHVDAINITDNQTSMTR
MCSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAASFDIHNMLCLSGDHQIFGDSP
QGQNVHDLDSMQLLQTVRRMRDDGKFLGGADIKRPPKIFAGAAANPFADPFEIRVPRLAK
KIAAGAEFIQTQCIYNLDKFEEWIRLARERGLTEKVYIMAGMTPMRSVGMARYMKNRVPG
MDVPDEVVKRMADTPKEKQAEEGIKICIEAIQRLKALEGVKGFHIMAIEWEEKVPEIVES
AGLYPRPDVD
>C6WT29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera mobilis (strain JLW8 / ATCC BAA-1282 / DSM 17540)|TrEMBL
MKTTTKKFDVSFEFFPPKTTEGMDKLRETRSQLAKFNPEFYSVTFGAGGSTRDRTMDTVL
EIQREGFQAAPHISGISSSKSEIRDLLQAYQTQGIKRLVALRGDIPSGEVSAGDFRYASE
LVAFIREETGSHFSVEVAAYPEFHPEARTPAADLQNLKRKVAAGANSAITQYFYNADAYF
RFVDQCDALGINVPIVPGIMPIYNITQLARFSSVCGAEIPRWLKMRLEEYGDDMASLRAF
GVDVVSELCETLLAWGVPSLHFYTLNQSNIISNIIENVQE
>A0A5R8KA60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phragmitibacter flavus|TrEMBL
MHIRDLLTPTRTTPTISFEFFPPNTTEASDRLTDTLQQLTPLAPDFVSVTYGAGGTTRHA
TQQLVTHLKTQTPLSPIPHLTCVNQQSHDIDAILENYATQGISNLLALRGDAPRHTTITC
NDFPFGIDLVRHIQKFNQRQFHPDPRGFGIGVAGFPEGHPATPNRLLEMDHLKAKVDAGA
DYICTQLFFDNREYHDFRERCHLAGIHIPIIPGILPITSMANLRRMAELSGGTRIPARLL
KALHRVQDDPAAVQQIGLHHATEQTFDLLHHNVPGIHFYTLNQSQPVLEILSRVGWKSTT
HTNLNRSYPTNH
>A0A496RQZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MSRISVELVPRHKEAFISELKLVKDTFSCVDTINIPDIVRYDLRSLEACELVKPLFNCAI
PHLRAGSIHREKPISFKSFLTEFGINEVLLVLGDHRDENILGCTTIELIRKFKIDLPQVK
VYAGIDPYRSSFEAEYAYIQEKISAGADGFFTQPFFDLNLLETYAKKLSNLKIFWGVSPV
LTRRAQNYWETKNKVVFPKGFVPEMSWNRKFALSVLDFSKASNTHIYFMPIKADLKEYLE
GIIF
>A0A423XVF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter malonaticus|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASPDELRTIARDYWNNGIRHIVALRGD
LPAGSGKPEMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVELKT
A
>A0A8B3RIH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium animalis subsp. lactis|TrEMBL
MHTPMFSLEVFPPKRTSPVGTIYDTLDGLNDMKPDFISVTYGTGKSADRTATARIAHTIH
SEYGIDAVAHLTAQYLTARDVDEALAMFDEAKVSGVLALRGDRNSEREPAGVFTHASDLV
CYIRERRPNLKIYGACYPEKHPQAATLDEDVAHLKAKVDAGASHLISQLFYDDDDFIAFL
GKARAAGIDVPIEAGIMPVTNAKSVRRMTNMCSSRVPRKLERMLEKWGDDPRTLREAGII
YASEQISDLVAQGVDGVHLYTMNHPSVSRRIWQNVGNLFEKA
>A0A4R5KRR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus piri|TrEMBL
MKLELREALRQQIIVGDGAMGTYLYQMGFPVGISYEELNLLKPDVIVDVHRRYYEAGARL
IETNTFSANREKLSKYGLEEDIEAINRAGVELARKAVGRDAYVVGAIGSIRAGRRKNFRT
AKIKDDLRQQIEILLDTQVDGLLLESFYDLEELLLALKIIRKLSSLPVICQFATEGTGTT
QDGVTLQDAFAKLEQNGADVVGFNCRSGPNGLLRSLERVAAIGGELPYSIFPNAGIPDYV
DGRFTYAATPQYFAETALKFADLGARIIGGCCGTTPEHIAAMSRALAGYSPGPARADRSQ
PTSAGAAVLPEREPVQPAAEVLAQPAPSAKPDGANEPNIVDLVKQRHTVIVELDPPRDLD
IDKFMKGARALKEAHVDALTMADNSLAVTRMSNLALGYLVKEQTGLRPLIHIACRDRNLI
GTQSHMMGLHTLGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEMIRMIKQLNEGVAFSGK
PLKKRASFIVGAAFNPNVKYLDKAVQRLERKIEAGADYIMTQPVYDAALVEKIYEATKHL
SIPIFIGIMPLASGGNAEYLHNEVPGIQLSDEVRQRMGSLKGEEGRAMGVQISKELLDTA
MRYFNGIYLMTPFLSYEMTADLTRYVWEKSGRAISTCTH
>A0A6B2CRN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrobaculum sp|TrEMBL
MEIIAEVTPVRDRAKLLKKLKALKPLVNRIDIPEAPGGKPTAHALAVGALAKQMGFEPIV
HIRLLDVNKTGLKSLLGGAYLLDIKDVVVLQGDPPAEGRPVGEVSTEEAVEEAKKMGLRA
GALLSLRRDHRKRVETLRADFYLALHLTDAKQLEGLPPIVYPYVMVRTSNNSELIDRLRQ
TAVEPHEALALVEALEGAAPGAVISVPGDFDALVGLLKQIKTRRG
>A0A4P8XID5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus algicola|TrEMBL
MKPDLRKAMADQVLIGDGAMGTFLYQKGFPVGISYEELNLTAPEVIRDVHKQYMKAGSDV
LESNTFSANYDKLSKYGLEGKVEEINRAGVRIAREAAGPQGYVVGAVGSIRGGKRNNISS
EELKRHFEQQIHAQLTEGVDGLLLETFYDVEEMLIALSLVRKNSELPVIAQFAVEDIART
LDGYTMADAFRIVKQAGADVFGFNCRTGPNGLARALETLQHVRSLPASVYPNAGIADYVD
GEYRYGASPEYFGQMALRFADMGARLIGGCCGTTPEHIAQISAALQGYQPMPLPVLEEAE
ERIVIQEKQEPASKQPGGEPTLVDLVRERHTVIVELDPPRDLDISKFMKGAEALKRAGAD
ALTLADNSLAVTRMSNMALGHLVQSQVGLRPLIHIACRDRNLIGTQSHMMGFDALGIDHV
LAVTGDPAKFGDLPGASSVYDLTSFEIIRMIKQLNEGVAFSGKPLKQKAGFVVGAAFNPN
VKHLDKAVQRLEKKIASGADYIMTQPVYDAELIVRMKEATKHLDIPIFVGVMPLASGRNA
EYLHNEVPGIQLSEQVRSRMAGLEGEEGRAMGVQIAMELLTTAVEHFNGIYLMTPFMFYD
MTVQLTQYVWELSGRSLSPLSH
>A0A6I6U510|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp. JH63|TrEMBL
MRPAPYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFFPPRDAEAESRLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSVAELRALVGAYADQGIT
NILALRGDPPGDPLGEWVAHPDGVEYAEQLVRLIDTLGDFHVGVASFPETHHRSPDIEHD
TRTLVSKLRAGAEYSITQMFFDVEHYLRLRDRVAAADPEQGLKPIIPGIMPVTSLATVRR
MVELSGSVIPPDVEERFAKAAGNGAEEDRASVRAVGIDFATEMAQRLVAEGAPCLHFCSL
NFAKATTEVLGRLGVDVDAALHVPA
>A0A7V8NDL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. AJS327|TrEMBL
MAIGISATRTDRPPTVRELLASGEQSFSFEFFAPKTAKGERTLWDALRRIEGVSPTFVSV
TYGAGGSSREGTVRNTERIATETTLTPVAHLTAVNHSRAELRNVIGQYADAGIRNVLAIR
GDPPGDPMGEWTRHPEGLTYAYELVELIREAGEFCVGVAAFPEMHPRSTDWDTDVRHFVA
KCRAGADYAITQMFFRPEDYLRLRDSAAAAGCETPIIPEIMPITNVGQIERFAQLSNATI
PRALQDRLRAVEDDPAAVRSVGIEYATEMSARLLAEGVPGLHFITLNHSTATLEIHQNLG
LQQRS
>A0A4P8L2I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoglaeba alkanexedens ALDC|TrEMBL
MKAGSNLEKVLTSGHFALTGELGPPRGANVEVIRKKAAFLRDKVDSINVTDNQTSVVRMS
SLAVCKLLVDMGLEPNLQMVCRDRNRIAMQSDLLGAYALGIRNVLCLSGDHNKFGDHPQS
KNVFDLDSMQLLAMVKKLRDEGRMLSGQECDGVPKFFIGAAANPFGDPFEFRVTRLAKKI
DSGVDFVQTQCIYNMDKFRTYMKMAHEEGLTEKCFILAGITPLKSVGMARYMAKFVPGLE
VPDYYIERLKGVEKNKQAEEGIKIAVEQIQEVREMPGVAGVHLMAIEWEERVPEIVEAAG
LLPRPSVN
>A0A5C5SXW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus sp. CPCC 101016|TrEMBL
MGLLNELKTRILTADGAMGTLLYSYGIEYCNEELNLQRPEVIEKIHQDYIKAGADIIQTN
TYGANAAKLARYGLEEQVAEINRAGISIAKRAAAPGGQFVFGTIGGIRGIRKSDATLQEI
IAMVDQQANHLLSGDPDGLLLETYYDFEELASTVKHLKGITDTPLIAQVSMHDPGILQNG
MTLNDALHQLETLGADIVGVNCRLGPHHTIQAFEEVTLPKHAFLSASPNASLLDVEDGRI
VYESEADYFGRAALLLREEGVRLIGGCCGTTPKHIAAAKKHLGSLPPITHKEVAVRKPIV
IREAEALEVKPLHEKAKTERTIIVELDTPRHLDTTKFLEGSVALNEAGVDAVTMADNSLA
SPRISNMAMGSILKHKENIRALAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LDKKIESGADYFISQPVYTKEKIVEIHEATKHLETPIFIGVMPLTSIRSAEFLHNEVPGI
KLSDDALERMRACGEDKDRATAEGIQIAKELIDTAAELFHGIYLITPFVRYDMTVELIRY
IRQLDQQKESDHSHVQTSY
>C6T731|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycine max|TrEMBL
MKIIEKIHAASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVVHNPSFCDITWSAGGTT
ADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVQHIRAKYGDYFGITVAGYPEAHPDVIESDGLATSEGYQNDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGINTLHLYTLNMEKSALAILMN
LGLIEETKFLGPYLGDALQMFSVLKKMSVQSFGQIVQKATYQGQ
>A0A127TTE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. A12|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPIINRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYTVDQIVDLVTQDVAGIHLYTMNNAEVAHQVHQATEALFHHKTKLEVS
>A0A4S8LHT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dendrothele bispora (strain CBS 962.96)|TrEMBL
MKLTDKIAAHSSPFPFFTFEFFPPRTDQGFENLVPRIGRLSSLKPLAISVTWGAGGSTKE
RSLDLAGLTQSNFGTDVILHLTCTNMVQGMVDEALLAAKERGIQNILALRGDPPRGKEEW
IPIDPKFQHGIDLVSYIHSKPELSSHFCVGVAGYPEGHPDNLISEETEMEYLQQKVDAGA
GFIVTQIFYNVDRFLTWIKKVRERGIKVPIIPGIMPIQTYSSFLRLVKLCGIDVPPSVRL
ALEDIKLDDQSVKNYGVQLAVDMIRQITAAGVVPGVHLCTLNLEKSVQRVLEQLQWTGVS
HSFQNKLISEETSNKAEPATDGRFVSPSAAANAATLGLANIPPSGTEVGSGELNKADSWD
DFPNGRFGDFKSPAYGDQGPWGNSGTVRPETLSEWGNPQSLSDLTTLFLNHLHSKINKTP
FSPGPLSAESLLILPHLEKLTKRGWWTVGSQPAVDGKESSDEVVGWGPKTGFIFQKGFVE
FFCTEEDLNQIEKQVEQKGEEWVHWFAANSRGECRGNVPEDGRNAVTWGVFPGQEIIQTT
IIEQENFLSWAEEAFSIWKNWASFYRPGSPERALLESVHHERWLVSIVHHNYKDASALWT
FLSEA
>A0A1M6PQB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera elsdenii|TrEMBL
MHTNELFAKKTVFSFEVFPPKRDIPVETVYPTLAELSKLHPDFISVTCGAGGTGGNRTVE
VAAHIKALGCETAAHMPCIYLTEEAALQNLKELKEAGIENILALRGDEVPGRERAHAFEH
ASDLIAFIKEKAPEFNVIGACYPEGHTEAKTLAADIRNLKTKVDAGASELISQLFFDNAL
FYRFLERCEIAGINVPIEAGIMPVTNKAQIERMVTMCGATLPIKFQRAIAKYGDTPESMR
DIGIAYAVDQIADLLANGVDGIHVYTMNNPYIAKKIAEAVKTLL
>A0A5J6VYF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. E76|TrEMBL
MSFFHANQREALNQSLAEVAGRINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIARDYWENGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFS
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPTV
>A0A5Y2SIA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella houtenae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2E7YZN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pelagibacter sp|TrEMBL
MNRNQKEFNIKKLLNNYSIETTPNVYEKYGKFSDLISTDNAVYVTYLPDENSSRVINTAK
KLTNEGFDVIPHLPARTIKDNNELEKYIGDLSEKAGCNKILVIGGGSNQKGNITSSLDIL
KTDLLSKYQFKEVGLAGHPDGNPDISEEELDKAIIEKNEFVKNVDYKAYLATQFFFEVSS
LEIWEQKLNLHNNKLEIHAGIPGPATLKTLIAYAKSCGIGNSIRFLSKQAINITKIMKTR
TPDKLIADLADYKEERPNSKLAKLHFYAFGGIKTTSKWLYDVINSNLEINSKNEFKIIEK
>A0A520J7B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
SDIDNLKRKLDAGASRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKF
AGLCGAEIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELA
YAICHMLGVRAKPFDKVAAA
>A0A1S8FIT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp. A23|TrEMBL
MNFPISFEFFPPKTPEGADKLRLARRALYAYKPEFCSVTFGAGGSTQDGTFGTVGEILKE
GVDAACHFSCVGATKATVRQQLAALQAMGVKRLVALRGDLPSGYGAGGEFHYASDLVAFI
REFTGDAFHIEVAAYPEIHPQAKSADADLQAFAAKVRAGANSAITQYFFNADAYFRFVDD
AKKMGLDVPVVPGIMPIISSTQLMRFSDACGAEIPRWIRLRLQGFGDDLASIKSFGLDVV
TDLCDQLRSAGVPGIHFYTMNQSQATVEICKRLGR
>A0A3M4ACJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas marginalis pv. marginalis|TrEMBL
MTMSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQ
LESEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYAN
DLVSFIREESGDHFHIEVAAYPEMHPQARNFENDLQNFVRKANAGADSAITQYFFNADSY
FYFVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQA
FGEQVISTMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3A9F2G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium 1XD8-76|TrEMBL
MNKVQISMEIFPPKKDSEFSSAFRVAKELAETDPDFISVTYGAGGSRSKSTVEIASYIQN
ELGITAMAHLTCVGSTQEDIRKMCGEFKKHNVTNILALRGDRPKDMSDEQYNGREFTYAS
NLVDFLREHTDFEIWGACYPEKHFESFSKEADLMHMKEKQDRGVTQFITQLFFDNDFFYE
FREKAARKGITAPIHAGIMPITSAGQIGRSITLSGSSVPKALSDIIASYGDSPEDMYRAG
IDYAVRQCRDLLQNGVDGIHIYTMNKPDVAKQIVRSIDTGR
>A0A2T7J583|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CS065A|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRIESVRPSFVSV
TYGAGGSTRSGTVRATQQIAADSTLTPVAHLTAVSHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWESDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFSRLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A3A3H9Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. DCY119|TrEMBL
MNPPRPPQIDENPAGIDLPLDRLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
GAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMERARDLGLTDQVF
VLCGVGPLASAKTAKWIRSNVPGIHIPDSIIARLEGAQDQKKEGKQLAIDIINEVKEIPG
VSGIHVMAYRQEEYVAEIVDESGVLKGRQPWKREVRRDDQLVADRLDHLLHDNVTETQVD
MVKTAH
>A0A7X0LIC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. JAI128|TrEMBL
MTSNLNSLAEARRAAASPLFADLEGDIGVSFEFFPPKTEKMEAQLWDTFRALEPLGPRFV
SVTYGAGGSTRERTHATVARIAAESHVAPAAHLTCVEASREEIDEVARAYWEAGVRHIVA
LRGDVPGGAPYRPHPDGYANAIELVAGLKAIAPFDISVAAYPEVHPDADCPQADLDNLKR
KMDAGATRAITQFFFSPDSFLRFRDAAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTQI
PGWMASLFDGLDDHPGARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPAAAPATEKAA
>A0A243FEC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis subsp. kyushuensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHEMKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A750KJW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6I4IHF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium profundi|TrEMBL
MKVTQHIERANGKTLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPSGLLQKKIVKKRPGTVGICAGIQNKYEVDAIPHVLCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKNEIYFKPEKEGNAYASDLVKQISNLNKGVYLDEDLQNSSCTNFCIGVAGY
PEKHMEAPSMDSDLHFLKQKIKNGADYIITQMFFDNQKFFDFVEKCKKAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMEVVKAKDNDAVKQIGIEWCLQQSKALIQAGIPVLH
YYSMGKAENIKAIASEIF
>A0A5C1FHV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. JAS24-2|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FILLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPKEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEMKEGIN
>A0A2S2GHI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SM18|TrEMBL
MHPLDTASAAVGTSLLEDFSLEMTGKDVPELEAADGTLPRGTRVNVTFLGNEDTRMRLDA
ARAVKRLGLLPVPHVSARRLTSRTDFAQFLAGLRDDGTATHVFTVAGDPVLPQGPYDSAL
ALIESGLLQEHGVRHVGIAGYPEGHPALTDDTLRSALRDKVASLTAHGLTGHVTTQFGFD
PDPVLSWLEHVRDQGITLPVRIGVPGPAGVRRLLSYATRFGVGTSASIAKKYGLSLTNLM
GTTGPDAFLRTLAERYDPARHGEVKIHFYTFGGLRATAEWIARFREDNPV
>A0A157RPG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella trematum|TrEMBL
MPTVLISPDIRRHAGRLIEAYSLEVGVKDLPALRTAASRIPPGTSIAIPYLPGQDDDARL
AAAVAVRALGFEPMLHLSARRIASQVELESFVARAVAEAAVQRCFVIAGDPASPLGPFGD
SASLIETGVFERAGIKEIGVGGHPESHPVMSPADRWAVLERKCGNIAQRGMSPLIVTQFA
FDADAVLAWLLALRERGIRCPVRLGVPGPAGVAVLARYAALCGVSACASMWAKYGLSLGK
LFATAGPDRFVDRLGAELTDTHGPVSLHFFPFGGIEKTVKWVEQYRAGGGGQ
>A0A1Q8JMM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. Ae356_Ps1|TrEMBL
MRDVRLDPCPKRMEFGPCGGVRADLTCELGTVPCPFTGGAAVPWTGPPGRSAAPAAFGHE
GPVVLTDLTSPPYDPAALGRIVRTIAGSCDALLIGQHHDEPDFPPTMLAVLAREAGGHPW
VTLTCRDRNRVVLEQDVAGLAAAGAEAVFCVTGDARGPSVRPDVSQVFDLDGTRLASLAA
AAGLPAVVPEAPDAPPTGLRPARLAEKQRAGAGAVVLNHAASPGRVAEFVTAARGHGATL
PVVAGVAVFTDEPGARRLEAFPGLEIDPAAVERVLTASDPVEAGIEAAVDEAVALLAVDG
VAGVNLSGRGSSGDDDTAAAIKAEIGHRIRSRAGTRG
>A0A257SXI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus ferrivorans|TrEMBL
MAHSVEFFPPKNAAGEARLREAIAALLPLGPEYASVTFGAGGSTRERTFATVEMILRDYP
LEAVPHLSCIGSTPEGIHEILERYRQQGVKRIVALRGDLPAGMDNPGSFQHASELVAFIR
AFGGFEIFVAGYPEVHPQAPSALLGIEHLVAKVQAGANAIITQYFFNPDAYAQLRDDLER
RDVAVPIIPGIMPIVNYEQIARFSAQCGAEIPRYVRLRMEAYGDDLAAQTEYGIELLSRQ
CETLLAQGAPDLHFYTLNQAEPTASIWRNLHL
>A0A450SWJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. DK|TrEMBL
MNTDKKPVFSFEFFPPKTPDGKNNLRAASQRLAGLGPDFFSVTFGAGGSTQSGTLETVRE
IRRETNIPTAPHISCIGSTRDKIRGMLDSYRAAHIERLVALRGDLLPGMKEPGELRYANE
LVEFIREETGDTFHIEVAAYPEVHPEAPSAEVDRQNFKRKVEAGADSAITQYFFDADAYV
DFVDNCRTIGVDIPIIPGIMPITNYTSLAGFSQRCGAKIPPRLAERLEGFGDDLESLRAF
GIDVVTELCRKLREAGAPGLHFYVLNRAEPAITIWKNLGLS
>A0A1J0EMY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas frederiksbergensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWSNLKLPR
>A0A318MSL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium asteroides|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLMPDFISVTYGTGRRSDRTATARIAKTIH
TEYGIPAVAHLTAQYADRQVIDQALDMFDDAGVAAVLALRGDSVEGREPAGVFEHASDLA
AYIRSRRPNLSIYGACYPETHPEAASPEEDIENLRIKVDSGVDHLVSQLFYDNADFLDFL
DRARAAGIQVPIEAGIMPITNEGQVRHMSEVCKARIPAAVESILERWGDDRASLREAGII
YASQQIADLVAHGVDGIHLYSMNHSGVTRRIWHNVRHLFRQVGANSESSSDKS
>A0A1E7GU90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium S3730MH5|TrEMBL
MKAETNLQKILAQGEFAVTCECNPPRGIDVDLILKNAAQLEGKVDAVNVNDNAVASVRMS
SWAMSKILLDMGIEPVLQMVTRDRNRIALQSDLLGALALGIRNVLCLTGDHPARGDHPEA
RKVFDLDSIQWIAAARQVRDQGCLMNGKEISGSPRFFIGGVANPFVESLELHIIRLQKKI
TAGAEFVQTQPVLEIEGFKA
>A0A073AZT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora rectivirgula|TrEMBL
MSSGQLQQAVSTRFEVLPLNDTAALVDHLPAGTTVTVTASPRRGLEPTLELSGRLQSAGY
RAVPHIAARSVSSTGHLVDVLDQLTAHRISEVFVVGGDSTAPAGPFPDALSLLRAAEELG
RLPERIGITGYPEPHALIPDDSTVQAMAQKSRYAHYIVSQMCFSAETITNWVTAVRQRGI
QLPIYLGMPGVVDMRKLMRIALRIGLGESTRYLRKQHGILSKLVNRYSADDLLAQLYPFA
NDPANGIAGWHFFTFNEVARTADWFQEFTTRHGEVSA
>A0A378TYE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria elongata|TrEMBL
MIPVFYLVIKQLNTYTAGIRKQKTKQAMTSPSKKLSFEFFPTRTPEGRAKQVITRKQLRQ
FSPEFFSCTSGAGGSTRDGTMQTIGDILAEGTAAAPHLPCIGMTAAEIRELLDTYKEMGV
RHIVALRGDIPSGMGAGTSGLRYANELVELIKNEYGSHFHIEIAAYPEYHPQARSAEDDL
NHFVRKAKAGADSAITQYFYNADAYFRFLDDVRGRGVDIPIIPGIMPIASFSKLVRFSDT
CGAEIPRWLRLKLQSYADDSAAIKALALDVVTEMCERLLREGAPSLHFYTLNQAGLVSTI
CQRLGY
>A0A0S2K9W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudohongiella spirulinae|TrEMBL
MDIKNPDARFSFEFFPPRTEAGMEKLMIVHQELAALQPDFFSVTYGAGGSTKDGTRQAVT
NISQAGSAVAPHLSFGGSSKEEILTLLESYRAMGVNRLVALRGDIPSGTGVASQYYYANE
LIEFIRAETGDHFHIEVACYPEIHPQSDSYDKDIYYFKKKVDAGANSAITQYFYNPDAYF
YFVDNCEKAGIEIPIVPGIMPITNFNNLQRFSNNCGAEIPRWIRQRLQSYGDDTASIRAF
GADVVLNLCEDLLAGGAPGLHFYSMNQTEPVRQIWQQLDLR
>A0A1V6JGN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin008|TrEMBL
MKVIDRLTQLKSTLFSFELLPPLKGHTIQTVFNTIDRLVAYNPAYINITYHREEVVYRPD
SRGGTEPVKVRRRPGTVGLAAAIQQRYNIDVVPHLICGGFDMHETEDALIDLDFLGIHNI
LALRGDADKVVGKFEPKIGGHRYAVDLVRQIDAMNRGEYLEKFMDKPKSTNFCIGVAGYP
EKHPESPNFESDLRHLKEKVEAGATYIVTQMFFDNSKFFNFVERCRSMGIEVPIVPGIKP
ISVREHLSLLPKIFGVHIPEDLAVEVEKCADNRQVYELGIEWAIAQTKELKNADVPAIHF
YTMGKPDNIATIAGSVF
>A0A6H1MTK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S1D4-11|TrEMBL
MDAEHVRALLSSVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLVGRLAAH
GYRVVPHVPARLLRDDAHLKDVVDRLRETGVDDVFVPAGDADRPAGAYDGALPVLRRLSE
LGSPFARVGITGYPESHPLIHDDLTIQAMWDKRAHATYIVSNLCFDPRVLGDWVGRIRRR
DVTLPVHVGVAGPVQRAKLLAMATKIGVGESTRFLTKHASWFLRFATPGGYSPDRLLARG
AEALTTPSAGVAGLHVFTFNQIAETERWRRALLDRLGD
>A0A7W0I093|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. CGMCC 1.16610|TrEMBL
MLKEKIESKEAGILTYGMTPPKITNTSDKVAEIARKQVERINDLDIDALILYDVQEETDR
VEQERPFPYLPTMDPATYSDEYLNQLRVPKIIYRCVGRYSEEQFVNWVKTDMEQDRYSVY
VGASSSKQEINLELSDAYDLSKRLNNNLTFGGVVIPERHMKKNDEHLRVNHKTQNGCSFF
VSQATYNVEASKNFLSDYYYYYTNNGLEMVPILFNLAPCGSEKTLEFMKWLGISIPTWLE
NDLKYSQDVLDKSLKLSLGIFEEILDFALEKGIPIGCSVESVSTRKVEIEASVQLVRDIR
AMLDKKLNRNVLTSI
>N8WT19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter guillouiae NIPH 991|TrEMBL
MSQLSQYFAQNQFCCLVEYLPSMQEILPVAIQLAGFPVCMTLSDRVRSDDDIAPLIAAQS
YPQQIEKVLHYAGKGRDIHDFNLFLTQAKQHGQQNLLLLTGDKLKQHHDGQGSHARTRYL
ESVNAVIAAKQQGGFHIGVALNPFKYSQAEKQAQYLKLHKKLQAGADYIITQLGFDLVAL
KQAHEFLIEENYTQKILACVMPLTLARAKFMLKHNVAGIVITPHMLEVLAQEHGSDQTEN
TYLRCALQILICQHIGYAGVHLSACHKADEQAILTGYIEQYRHLDLKQCQQLWDQLWQLK
TGNELRPAVVEKSKLSNLQQKVKYQFLDTIHSTMFNSSLVKGLGAYIFSAGFWNKALAAK
LLLQAEYLSKHFIVGCESCGQCRLAETLYICPETCPKGLANGPCGGTHLDRCEFGDRECI
HSVKARLAEEVDQIQVLKKQLIPTVPIEVRGTSSWKNWYVKQ
>A0A7X8DD62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKHNHSTDNALVLYDGAMGTYYRWLYREDYSLLEAVNLSKPDRIKQIHQAYIKAGATRLK
TNTFAAFPLMLEKSADQVKQMVLAAWHLANEAIYELKAQDTVKAVADIGPYFVLQSGLAD
NLKIQNQQAYLDLAKIFIDVGVEEFLFETQEQLTDLIPAIKLIKSYNPNAKITVSFSVNQ
NGFTRIGLSLRELLAQAEKIDEITFTGLNCTLGPTQLGQVFAEHAQFSKFCFFGPNSGLP
ERDLGRGRGGAEAKYFAESCQRAWDNGAYQLGGCCGTNPLDIRALADLFKNKKPVIVKKI
ESGLEFAVSEQPSIKTEISKKSWYERLLTGEQIIAIEYDTPTKANIKTYLEKVVQLKDAG
MDLMTIADNPNGQTRIDSALMASRIKQELGIDVLPHFTCRDRNLFAIHSLLLGLATCDVH
QILAVTGDPIPLEDRNQIKSVFNVNSQSLLRYISQLNQELVQPFILCAAINVNAPRFDME
LKKTRRKIESGAQVFLTQPIFTERGKENLMLAKQELRDQAKFLAGIMPLVSEKNALFMKY
EMSGMDVPDEIIKRYANLNREQSEKIALEISREIMTNLSKVTDGFYLITPFQRTHLTARL
CQEWKSNKK
>A0A094GYT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4520|TrEMBL
MKTTWKDIQPVPTSQEFLDIVLSRTQRRLPTQIRAGFQISRIRNFYTRKVKFTQETFSEK
ISLILDGFPRLQDIHPFHKDLLNTLYDADHFRIALGQLATAKHLIETVSRDYVRLLKYAQ
SLFQCKQLKRAALGRMATICKRLKDPLLYLDQVRQHLGRLPSIDPNTRTLLICGYPNVGK
SSFLRSVTRADVDVQPYAFTTKSLFVGHFDYKYLRFQAIDTPGILDHPLEEMNTIEMQSI
TAIAHLRSAILYFMDLSEQCGYTVAAQIALFQSIKPLFANKLVFIVINKIDVMRPEDLDP
ESQAQLQALLKPGDVEMLQLSCTTEEGVQEVKNAACERLIADRVAQKLKAGTNSNGAVGG
RLGDVLARIHVARPMNGVVREAFIPEAVKEMKKYDKNDPERRKLARDIEEENGGAGVFNV
NLKDKYMLENDEWKYDKVPEVLDGKNVYDFIDPEIEAKLAALEEEEEKLEAEGYYDSEDD
LEDAEDADIRMKAELIREKRILIRNAAKMKKSLKNRAIIPRTLTKAKLTDMEDHLDSLGL
DTTSLTTRARSQSRGRSVLRSRTGTEDVMDVDSPEYEAKMRAKSRARSQSNRREDGVPEG
TARTKAERIAKLGQRHRNRMARAGEADRHVAAAMPKHLFSGKRGAAKLQLHRGFFNCMVG
KPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHAQLTCEMVSVAQSVY
GLETCMHLTCTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEKWVATDEGFQYARDL
VGYIRKTYGNHFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATFIVTQMFYDVPNFLD
WVRKVRAKGISIPIIPGIMPISTYASFLRRCNHMNAKIPPGWIEAMEPVKNDDAAVREIG
RGLVTGMCRAILESGINHLHFYTMNLAQATRGVLEQLEMLPSEERPLKQALPWRQSLGLG
RRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDAYGIGLKGSNEQNIK
LWGEPKSVKDIANVFLRYLNADVESLPWSEAPISNEADVIKNQLVGLNERGLLTINSQPA
VDGVKSSHPVYGWGPLNGYVYQKAYLELLVAPELIDELLDRIAKDPEVTYYAVTKTGTLR
TNAPSDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDWAHCHEASSPSRNVI
QRVMETYYLVNIVHNDFHQRDGLFSLFEGLSVPNIDQPAEGDVAPAAAPTPAAAAAPATN
GNKVEDAPAAIVSNVLPVA
>A0A7X8G628|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKISDMFKNNKQTVSFEIFPPKLTTPIETIFDKLGDFASMKPDFISVTYGAGGSKKGRTV
EIASKIKGEYGIESLAHFTCVGHSIEEINALIKEMKDENIDNLLALRGDPPADNPDFDFS
KNVFAHASELIKHIRSKENFCIGAACYPEGHVDSTRIKHDLHYLKLKVDQGVDFLITQLF
FDNRIFYDFLDKLITYNITCPVLPSIMPVFKADQIKRIASMCGASMPAKLVLLLDKYGGT
DDMQKAGIEYASEQLKDLLDNGVDGVHINTMNRVDATQTIMQNIGKL
>A0A7X6VEH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
IMPIFNARIKTMTARSGCSIPANLVLMIDKYQDSPEDLKKAGEEYAAYMIRELLDGGAPG
IHLYTMNKLESTKNILKLAGLR
>G3PGI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gasterosteus aculeatus|TrEMBL
MVNQVQRGDRSSQSCKSDSSGGESSRESSRSSTPVLDGDRCDRLRDKMRRRTESGDRWFS
LEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCG
LESILHLTCCDQTKGKITGYLAKAKHLGLKNIMALRGDPIGADWEEEEEGFNYATDLVKH
IRSEFEDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTFLKFLD
DCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITRVIEPIKDNDAAIRNYGVQQ
AVEMCRVLLDSGKVPGLHFYTLNREVAIMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVED
VRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSPKDALLQMW
GDELKNEESVFEVFTCYITAQTNCNGHKVLCLPWNDEPLAPETNLLKDELEKVNRRGVLT
INSQPNINGKPSADPIAGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKNYEPRVNYHIV
NVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWAKLYED
ESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWQVIDDMFKMLDAPPEPEDGSVSE
>A0A399IEK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
MNILDRLKSEVLTGDGAIGTMLYAKGVSLDSNFEHLNLVRPSLVRELALEYIAAGAQVIE
TNTFGANFTKLAAIGLGHKVSEINRAGALIAREAVLGHPGILVAGSVGPLGKPKGADQEL
TGDEMVEVFRSQCHALADGGADLLMLETFSSLEQLAAAVRAARETGLPVSASLAFMEGGR
SGDGSTVEEFCGAMEEAGADLIGANCGAGPLELVKVVRRLAGLTDKPITAYANSGFPEYR
DGRYIYRATPDYFAAMAREMAEAGANLIGGCCGTTPAHIAAMAAVLSGRHPVVRTRSTGI
TVAGGLEKKPLKTRSFLDGWGQRKIITVELDPPKGLECNRIIEGSRRLKEAGADAINLAE
NPLARPRMGNIALGSIIQHEVGIEVIVHVTGRDRNLIGMQSDLMGASLLGIRSILAVTGD
PASMGDHAGAKSVFDLHSFTLIKLLADLNRGVNANANPIGHGTGFTIGAAFNPNTGNMAL
QADRLRRKVANGAVFAQSQPIYDPALFLEALELTHDCNIPLLPGIMPLVSERNAEYLHNE
VPGITVPDAVRARMKGLEKEAGVREGVAIAKELIEATFTAAGGYYLIPPFGKYELALELI
DHIHLLEREHQ
>A0A316N986|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MTVQEYLKEKPLLFDGAMGTYLVEKHPETVKRNCEFMNIEHPEWVQKIHEKYLKAGAVAI
KTNTFSANTVVLQQPVEKVKEMIKKGYQIAQNAIKDFAGERFIFADIGPVPINEEKDLLE
AYKEIANTFLECGAQNFLFETMESREAIEEIASYIKEKAPGSFIAVSFAASPEGYTRGGF
FVKKLFWDLQQSESIDALGFNCVSGPKHLLDLVQRLDKKKIKKYLTIMPNAGYPTLLGNR
MYYEQSYTYFSNNIEKLLEEGVAMVGGCCGTRPKDIKGVAEMMQQKQDRFVTWIEKRDRK
LVQAAGYKEELESTHIVANKNEHNTFAKKLFAGEKVIVVELDPPIEPDIDFFMEGAARYK
YAGVDAIDIADCPIAKARIDSSILACKVTRELGLTTIPHMTCRDRNINATKALLLGLNVE
GVNNVLTVTGDPVPTAMRDQVKTMFSYNSAMLARHIQSLNEEVFEENPFMVSGALNINAL
QFDSQIRHAKKKIENGVSVLFTQPVLSERGFANLKRAREELDVKILGGIMPVVSYRNACF
MNNEMAGIDVQDTIVSMYQDKNREEGEELAYRISTAIIDKITDYVDGYYLITPFKRVELL
LRIIHYVKNKNNR
>A0A7X7CP64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKLIELFKKKKPVISFEIFPPKLDTPLESIYSTLEQFKELKPDFISVTYGAGGSAKDRTI
EIASKIKNEYGIECMAHLTCVGHSENELDLMLSSLEDNKLENILALRGDPPVNQPDFDFS
KNVYKYAYELIRHIRSKNNFCISAAAYVEGHVSSTRLKDDLLYLKQKVDTGVDFLVTQLF
FDNRIFYDFLDKAASVGINCPITPGIMPVFKADQIKRITSLCGASIPAKLLIIMDKYEDS
PEDMRKAGIEYASRQISDLIDN
>A0A7W8KYX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. AK015|TrEMBL
MKITEHIANANGKTLFSFELIPPLKGQSIQGIYDAIDPLMEFKPPFIDVTSLREDYIYKE
HETGLLEKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLQFLGIDN
VLVLRGDARRGDASFVPTPNGHCYATDLLQQVVNMNNGVYLHEHYEGIMKTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKIDMGANFIVTQMFFDNQKYFDFVNNCRAVGINVPIIPGLK
PITTSKQLVNLSKTFHIDIPEALSDAIHDCKEEKHVKDIGIEWMIEQCKELVKFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A7X1AVA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceicoccus vermicola|TrEMBL
MNFFREIWSSGRPVCSVEFFPPKNQETEKQFHLTAERLKAYRPDFVSMTYGAGGSSRDRS
IGFGLQLRENFGYEVLPHLTCVGHSRDEMRSILDDFEESGFQGIMALRGDPPQGLTEFKP
HPDGLRYASDLVQFIRETHPSFATGVAGYPEKHPESPNADEDLRHLVSKVSAGGDFITTQ
LFFENQDYFRFVERCRAAGITVPILPGILTAVSWKQVSRFCDMCGSRIPPALASQLEEAA
GDSEAEAEVGINWAKNQVIELLQAGAPGFHLYILNRSKPALELMRRLDQELGADFRSIPR
DDSSVL
>A0A7X6Z7D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
GIRQVLAVTGDAIPESDRGFVKPVFNLNSIGLLQLIGQMNRDPFAGDPILAAAAVDPGSP
NHDAEYGRACRKQEAGAGLFLTQPVFEERSLELVGRMRGAGMKVLIGLMPLLNWRNAQFL
SHEVPGIRIPETILGRFFPKQDKEEALETGLAVILDLARRFRTQADGFYLIPPFNRSALI
SRFLARLSAENIVGQKGVSHDFDR
>A0A067Z6N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter oxydans DSM 3504|TrEMBL
MNTNLKRLLSGTLADHPSLCHSDMPVPVLSFEVVPPRTDAMERRLWQCVRRLAPLSPRFV
SVTYGAGGTMQARTQATVLRLKQETTLVPAAHLTCIGATREEIDDIARTYWQAGVRHLVA
LRGDAPAGTDYTPHPGGYAYASDLVAGLHRIADFEISVAAYPETHPTALSSQADIDNLKR
KFDAGASRAITQYFFEASTCLRFLDRCLAAGITAPIVPGIMPVSNYDQITRFSALCGVTV
PAWMTHLFEGTAKNPELCRIAACIVAAEQVRTLQSHGINEFHFSTLNRPDLTCAIAHLLG
VRPASETDS
>A0A094J3L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4520|TrEMBL
MADSPTTDKITDKIAALPQDASYFSLEFFPPKTAMGTTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSRALVDDALSAAKEAGIQNILALRGD
EPRGEYKDALEEGKEGEDEFVWAIDLVRYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
EHDLPYLVDKVQAGADFIMTQLFYDVDAYDKFEKILRDHSSGAFKTLPIIPGLMPIQSYQ
ILRRTTKLSNAKLPQSIIDRLDAVRTDDEMVKKVGVDILAEIVESVKATKKRTQGPKGFH
FYTLNLEKAVAFILERANLIPSFTPILTSDVFAVDDITDTIPLPQLLINGERKNRRQSSV
GSGPHNFVIIDREEASGFEATGAEAAVPKEGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRPDITSIFVQYLNGTLSALPWSDE
PITAETNLIKDELVKLNQKGWWTIASQPAVNGARSQDEVVGWGPKGGWVFQKAFVELFVP
TSDWARLKPLLEGNEEVSFLAQSASGEFLKSKLDLGPGEEGSETNAVTWGVFPGKEIVSP
TIVEEVSFRAWAEEAWQMWGEWAAVFGKSGEESRRFLDGVARDGWLVNVIWHDFVGMCKA
KEGRSEEEGYKGLWDVLIEA
>A0A1V5L3V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin456|TrEMBL
MESACSKLKQTLTSGRLALTAEIGPPKHASPAGVAANARLLKDYVDAANVTDCQSAVVRM
SSLAASLHVKQNGLEPVFQMTCRDRNRIAIQSDLLGAYSLGIRNILCLSGDHQVFGNHPT
AKNVYDVDSIQLIQLIRRMRDEKLFFSGEAILEHEPRFFIGAVANPFADPFEYRVDRLEK
KINAGAEFIQTQCICDMERFSRFMEICVSRGLHQRAYILAGVIPLKSWRAAWYMQTKVPG
MIVPEELVQRMKKAEDPVAEGLEICAGQIKFIREQIKGVAGFHIMAINWEEAVADVIGRA
GLGRCGEALPRDEGPV
>W8PR76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas brassicacearum|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
QDVITQMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1G8E7W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter subterraneus|TrEMBL
MSPPSKSAHSVGPPASEPYPALSYELFPPRSTSAAETLWCTIRELEQTSPDYVSVTYGAS
GSNRDTAVDLLSRLLTETALRPLAHLTCVGNTREYLLDLVDELITLGVRGILALRGDTPK
DPGAGPGDLSYASDLVKLVREAERRRTAHLCAGRLAVGVAAYATRHPESPSFDHDIEALL
AKQAAGADFAITQVFFFPDHFQRLVAAARRAGVDIPIIPGVMPLTSVRRLDRLSELAGIE
MDYALRDRLAAAEDDAARRRIGVQATVDLANAALDAGAPGIHLYTFNEHAAALDVLDSLQ
LRRPPVPRGLVRTA
>A0A2V3ULF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. B4|TrEMBL
MPSESRHRASRDGFRPIRVSIEFFPPKTEEMENILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVNATREEIDAVVQSYWDAGVRHIVALRGDPAEGVG
HTYRPHPGGYAQTCDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFDNEIYLRYLEKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLENDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
VATQKAA
>A0A317CDH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucothrix arctica|TrEMBL
MLVDKIKNRESGIVLYGIVPPKAGSPAEKVAEISARQIERLQGLDIDGLILYDIQDEASR
TSEGRPFPFMETLDSFEYSREYLSALNVPKVIYRSVGKYSEAELTNFVTSLDPQQELTVF
VGASSKDQAVTMSVSDAYDLRRAKNSDVLLGGVTIPERHESKSDEHLRVFNKMKQGCSFF
VSQGVYDVNASKNLLSDYYYYGQEHNIPLVPILFTLTPCGSQKTLQFMKWLGISIPRWLE
NELLNCHDILQQSVDVSEQNWLELKAFADEKNIPIGCNIESVAVRKEEVEASIELLNRIQ
K
>A0A1Y4RPG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp. An138|TrEMBL
MGMLEKALESGKFGVTVEMAPPKGYDFTEQMEAAELLKGKVHGVNVTDMQSACLKASSLG
LCIKLKQAGLDPIIQVTGRDRSRMGIMGDMFSAAAFGIDTMLALTGDHPTVGDCKQSKPV
YDLDSVGILHMLTAMEATDRDCGGNEIEGGAPVFYKGAVVTPVYDPLPLQINKLRQKVEA
GAQYIQTQGIFDIESLKRFMDEVDKANIHTHIMAGIIPLKAAGMARYMNENVPGIAVPQD
MIDRLAAAAAEGKEKGVKGLPTQLGIEMAAEMIAKIKEEGICDGVHIMAIGAEKNVPKIL
EKAGLTIE
>K9QZ94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. (strain ATCC 29411 / PCC 7524)|TrEMBL
MEHSHSCNYSTLNNFRKSAQAGEFLVTAEVAPPKGGNPTHMIEMAATLKGRVHAVNITDG
SRAVLRMSSLVASAILLQHGIEPICQMACRDRNRIGIQADLMGAHALGIRNILALTGDPV
KAGDHPEAKAVFDLEAVRLLQLIRNMNQGVDSHDKPLTDGATDLFAGAAVDPQSDSWSGL
QSRFERKIEAGAQFFQSQLITDFERLEKFMDKIASVHNKPILAGIFLLKSAKNAQFINKC
VPGVNIPEHIIDRLAKAKHPLEEGVKIAGEQVQIARQLCHGVHMMAVKREDLIPKILDLA
GVTPVNQVLAK
>A0A2M9YV54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira barantonii|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTQEGDAKLMETVKELSGLNPDFVTVTYGAGGSTRDK
TAQILSEISKKYSFSTVSHFTCVGANREQILETLKGIRSSGITNLMALRGDPPKGEGDFK
KTEGGFGNATELISFIRSEKLDFCIGGGCYPEKHPNANSLEEDVRHLKLKVDAGTDFLVS
QLFFTNSIFEKFLNLVRKVGITVPVIPGIMPITSFSQIERFRSMAACEFPSSLIADLQEV
EHRPEEFYRRSLNFTVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKG
>J0BCE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae (strain WSM1455)|TrEMBL
MALKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTRAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESHDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRRQTKSAGAAA
>A0A5B9QDY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bythopirellula goksoeyrii|TrEMBL
MTTLAQAYGRDRFGLSFELFPPKTDAGVENLWFHVDRLVQYKPSYITCTYGAGGSTQDRT
LEVVAHVRSKFELPVATHLTCVGNTADQLRAYLHRALDLEIDNVVALRGDPPKGETSFRS
VEGGFSHANELVKFIRDEFHHMGIAVAGYPETHQEAVSAEADLTNLKRKVDAGADIVITQ
LFYDNADFFAFRDKYQAAGLDVPLVPGLLPVTNGAQIQRISSLCGAKLPPDFLAALSEHE
DGSEGQFEVGVEFATKQAAELVAAGVPGIHFYVLNKSEATERVLRDVQLPR
>A0A2N6FW30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp|TrEMBL
MLTDKIRNKESGIILYGITPPKINHTEEEIKEIAQRHIDRISKLNVDGLVLYDIQDESDR
TDEKRPFPFIKTINPCEYSKNYLQELKTPRIVYRAVGNYTSERFTAWLEDTTQSQVHSVF
VGAASHEQQNNITLKEAYALKRKVNDNLCLGGIAIPERHMKKHDEHLRVFSKKNNSCEYF
ITQCVYDLHAAKTFLTDYAKYAKENNIEVVPIIFTLTPCGSSKTLDFMKWLGINIPNYLE
EDLKESGDILKESVKLSRDIFEELYKYGLKKGIPVGCNIESVAIRKAEIEASVELLDEVK
GIIKKYS
>B8IH84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060)|TrEMBL
MASTAFRPSRESHRPIRVSFEFFPPKTAEMEATLWSSIERLAPLQPNFVSVTYGAGGSTR
ERTHNTVARIVRETNLKPAAHLTCVDATKEEVNEVVRSYWDVGVRHIVALRGDPAEGVGT
AYRAHPGGYARSCDLVAGIKGIGDFQVSVSAYPERHPEAPSLDVDIDALKAKVECGADRA
ITQFFFDNDLFFRYLDRVQARGIDIPIVPGILPVQNFKQAASFAKRTGASVPDWLAARFE
GLEDDVGTRKLVAAAVAAEQVLDLLDRGVTDFHFYTMNRADLVYAICHLLGLRATPSAPM
PERAAA
>A0A2G2HEY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp|TrEMBL
MLKQKILNKENGILLYGLTPPRHTHSKEQMNXIAQKHIQRINTIDIDALVLYDIQDESDR
TAEKRTFPFVGTLDPYVYKNQYLSELNIPTIVYRAVGKYNKNDFSSWLXDTKNENNYSVF
VGAASKXQDIKLSVKEAYALKEEINKDLXLGAITIPERHTIKKDEHIRVFNKIDQGCKYF
ITQCVYNLEAAKIFLSDYARYAKEHNKEMVPIIITLTPCGSSKTLEFMEWLGINIPNYLK
EDLLDSKDILQESLDICLNIFTELNKFALKRGIPLGCNVESVAIRKEEIDASIVLLKEVD
VIMRQNITK
>A0A2D5JCX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp|TrEMBL
MFETLLQKLQEDNYLTLETTPQHEPSMHNIIERIKKFKLQNKVDGFSCTDNPLAKLKYNA
LFASLKLQMEFEKPVIATMSMRDRNKIALQSDLLGASDFDVRAILALTGDPAKMSDQPHS
KGVFESNSLMLLKIIKSFNYGMDFAGHPFKIEPKQIFPFSVVNSYAKNFATLEKKMHNKI
QNGSLGIISQPVFDIDNAKKLLESFDKAKADVEGDKKKSQLIFGLFPITKLRTALFLEAQ
VPGIHVPQYWIDQLENAHKISPEEEYKVGMRLSQDIYKEIRKIHPKIHLMTANRFDVANE
VIS
>A0A520MQT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thioglobus sp|TrEMBL
MATNPEIQSQEAQKSGSNLERVLAAGHFAVTGELGPPKHMDQAFIDRKINLLKGVVDAAN
VTDNQTGIVRLSSIATGIYMAQQGLEPVIQMTCRDRNRLAIQSDLMGAYFHGIRNVLCLS
GDHQSFGNHPGAKNVQDIDSMQLIQMIKEMRDKNQFQCGDEIKGGGPKLLIGGAGSPFSE
PISFRPLRIAKKMAAGVDFIQTQMIFDMDIFKQFMAKLVDLGVTEKVHILAGIGPLKSSP
MARFLNDQIPGIVIPDELLKRMDGAVQGIDENDKDARRDAWRAEGQNICIEQIEQLQEIE
GVAGVHIMAIEWEAAIRPIVERAGLFPRPQV
>A0A1L6I2Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. SOS3|TrEMBL
MNPIELSFEFFPPKTPEGVEKLRATREQLLALKPKFVSVTFGAGGSTQQGTLDTVLDMSK
GGLEAAPHLSCIGSSKDDLRRILGEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAESGDWFHIEVAAYPEYHPQSRTPRHDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGLDV
VTGLCQRLVDAGVPGLHFYTLNAAASTRTICERLGL
>A0A3M5TX11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. primulae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A4Y3VAL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces spinoverrucosus|TrEMBL
MRDMLATGKTTYSFEFYAPKTAKGERSLWNALRRVEAVAPDFVSVTYGAGGSTRASTVKE
TQQIVADTTLTPVAHLTAVDHSIGELRNVIGQFADAGIRNMLALRGDPPGDPMGEWVPHP
KGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVEHFVDKCRAGADYAITQMFF
QPESYLRLRDRVAAAGCETPVIPEVMPVTSVRMLERLPQLSNAHIPSTLKERILTAKDNP
SAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPRA
>A0A1C6P4N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. HW608|TrEMBL
MRLPLSFEFFPPKTPEGAAKLRAVRQQLYAMSPEFCSVTYGAGGSTHDGTFGTVREILGE
GVSAACHFSCIGATKATVRTQLAELKAMGVKRLVALRGDLPSGYGIGGEFLYASDLVAFI
RAETGRDFHIEVACYPEVHPQAKSPEADLKAFVAKVRAGADSAITQYFFSPEAYWRFVDE
VRALGIDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASIKSFGLDVV
SALCARLREGGAPALHFYTMNQSAATLGVLERLGWSA
>A0A2I1MEF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VYYIRSKRPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGVNVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNADCLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A2U2S7L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ardenticatenia bacterium|TrEMBL
MPLFSPRRYQAPFMPVQRDSLPVQVFTAFEQAIKGALFGCRMCGNCILQETAFVCPMTCP
KGLRNGLCGGATPDHCEVDPSRPCTWYVIYERSERMGRLDKLLEINAPVDGNRVGHETWL
DMIKLWFKRKAGPYPWDFVFNRAKFNREWEEFFYALRQPDWWQGDSQYHPPAYTEPISLL
EANLRSGVFTVTAEIAPPLDASPEGLIKKVNMLKPYVTAANFTDNASATCRMNSLASSKL
CLDAGLEPVMQLQARDRTRVVIQSDAVGASGLGIRNILCLTGDHHRFGPAPMAMPDQFDM
DGVQILWMLRRMRDEGKYIDGREMKIRPKFFLGAAASPFGAPPKYEAIRAEKKINAGAQF
IQTQPVFDYNRFTEWLEALDKRNLLNKVYILAGIVPLRSAKAAHFMKDVPGVVLTESDLK
RMDSAGDKEAQAEMGVTIALEMIERLKNTPGIHGLHIMAVHWESIVPRLVEEAGLPRPVV
RELPRPEVAREQEKEAVPAS
>A0A8F8NVX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. K15/93|TrEMBL
MTSTPDTGRSDVSISFEFFPPKTPDMEGQLWAAITELTEWQPEFVSVTYGAGGSTKAPTL
NTVRRMIAETPLPTASHLTCVSATREDTHRVVDELRAAGVRHFVALRGDPPGGIGTAYQP
HPGGYENAAALVAGLRDIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDVFETYMERVRAAGIAIPVLPGIMPIQNLTQLKRFAGMCGTSIPSYLDERFAGLDD
KPEERAKVAADVAAEQIEDLVRRGHREFHLYTMNRAPLVGAVLERLGFKRTKIAAAAGAA
A
>A0A7R9NCC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MKTALSKGHFVVTAEFYPPKEANGSEIKERALVLKDVVEAVVVRDNPLAQVHTSPIATAT
LLLNVGLAPIVQISIRDKNRLAIQSDILGAVTLGVKAFFCLEDCHQRVGDNPGAKGVFDL
DCVQLISIMKKIEHSLVGTRINPFAHPLELHLINLSKKINAGVDFIQTMPVFDLERFKEF
ISLIKGENLYLLAGVRPIKSWQALQSMSQMVIPENIVQRIKNSPENKQAEEGIKICVEII
KALKQIKGVNGIHIFAHDWEEAVPILVRQANLK
>A0A062WQ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. BMG5.23|TrEMBL
MWLWSVESYPVRMREPTAGHERPVRGFEMICEIEPPTRPDLTHARHQIGVLSPVTDAFLI
PDNHIGRATVSSIAVAHEVATMGGRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVHG
DKPTAGNRTGDLTVRAMMDEARAASEDPVFADMPAFRVGAAAGLRPLPTWKRAADFLFVQ
ISYSVDALLRWRDAHPVELPIYAGVMVLASAGMARRLAAAIPDIDIPDDLVQAVERDQAA
GVEAACDQVLRLRDSGAFAGVHLVPVSRYRQVATRLEDLL
>A0A4U1ALV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila sp. IMCC35006|TrEMBL
MKSGSNLEKVLAAGHFSVTAECGPPRGADPDIVRKKAAFVKGNVDACNVTDNQTSVVRMS
SLAGCLLIKEEGIEPLIQMVVRDRNRIALQSDLLGASAMGVRNLLCLSGDHQKFGDDPQA
KNVFDIDSMQLIHLAKTMRDDGVFPSGDKLQGAPMFYIGCAVNPFADPFEIRVPRLKLKM
EAGADFVQTQCIYNMEKFKKYMELAKREGLPEKIKILAGVTPLKSAGMAKFMRKMVAGMD
IPDAVVNRIAAEPKEKQADKGIEMCIEQIQELKEMEGIAGVHVMAIEWEEKLAEIVGGAG
LLPRPVVE
>A0A3N1IF90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PanSC9|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSSQWDTDVQHFVD
KCRAGADYAITQMFFRPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPKLSNASF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A2S7YXZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella rogosae JCM 15642|TrEMBL
MTLREKHQQGKFTITVELDPPKSSSAEKVFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDAPTSFYIGATGNPGAPDLEIERQKLAAKIQNGA
HFVQTQPIYDLEQAKRYIDTMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A3Q3MFC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mastacembelus armatus|TrEMBL
MVNQVQRDGGSWQSCKSDSSGASNSGGESSKESSRCSTPVLDADRADRLRDKMRRRMDSG
DRWFSLEFFPPRTASGAVNLISRVILSTDCIFDRMGSGGPLFIDITWHPSGDPGSDKETS
SMMIASTAVNYCGLESILHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPMGTDWEEE
EGGFNYAVDLVKHIRSEFDDYFDICVAGYPTGHPEAQSYEQDLRHLKEKVDAGADFIITQ
LFFRADTFLKFLDDCRANGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIK
DNDAAIRNYGIHQAVEICRVLLDSGKVPGLHFYTLNREVATIEVLRQLGLWKEDPRRPLP
WAISAHPKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYL
KSKSSKDALLQMWGKELMNEDSVYEVFTCYITGQPNRNGHKVMCLPWNDDPLAPETNLLK
DELEKVNRRGVLTINSQPNINGKPSADPIVGWGPAGGYVFQKAYLEFFTSSENVNALLKV
LKKYEPRVNYHIVNVHGRNLTNAPDLQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAF
ALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLQSCLWQVIDDMFELLDAPTE
PLRDITV
>F4AV59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dokdonia sp. (strain 4H-3-7-5)|TrEMBL
MTKVRDHIAKAIEEKRTDFSFEILPPLKGQNINTIFDNIDPLMEFKPPFIDVTYHREEYI
YKEREDGLLEKKVVRKRPGTVGICAAIQNRYQVDAVPHVLCGGFSKEDTENFLIDMDFLG
IENVMALRGDAVKSETYYKPNKNGNIYAQDLVEQIIDLNNGTYLDEDLQNSAKTDFCIGV
AGYPEKHLEAPSLESDIHFLKKKLEAGACYVVTQMFFDNQKYFDFVDKCRAAGITKPIIP
GLKPLATKKQLNLIPQRFSVDVPDALVMEVVNAKDAAAIRQVGIEWCIQQSKELKAAGVP
VLHYYSMGKSDNIRQIAAAVF
>J2XBS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM80|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFIRKAKAGADSAITQYFFNADSYFY
FVERLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A3N1HV75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PanSC9|TrEMBL
MNPALTAPPDGGTPGPHGAESQERTTGLLDDFSLEMTGKDVSRLEEASDGIPPGTRINIT
FLAGEDLATRLTAARAVRRLGFVPVPHISARRLPSRAALQEFLSGLAADGTAENVFLVGG
DPARPEGPYADALALLRTGLLQEHGVRHVGISGYPEGHPAIPDPTLWSALTDKAAAIGAH
RFGGDVITQFGFDPAPVLGWLEAVRARGVHLPVRIGVPGPVGVRRLLGYATRFGVATSAS
VARKYGFSLTNLMGTTGPDRFLHALAERYDPARHGRVKVHFYTFGGLRTTAEWVARFRHE
DHTPTGRP
>A0A3S9B2X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Georhizobium profundi|TrEMBL
MSLLRRSSPSLSADRINVSFEFFPPKTGDMETQLFESVSKLAPFNPDFVSVTYGAGGSTK
QPTLNTVSRIHRETTLSTAAHLTCVDASREEVDAVVREFWDVGVRHFVALRGDPSGGIGT
RFKPHADGYANAAELVAGLKAFADFEISVSAYPEKHPESPDFMTDIDMLKRKVDNGATRA
ITQFFFDNDTYERYVERVRRAGIYIPIVPGILPIHNFGQVARFAGMCGASIPTWLAERFE
GLEDDAQTRSLIAAALAADQVMDLVERGVHDFHFYTMNRAQLVYAICHLLGLRGRAPQAE
DKAVAAA
>A0A6M0QVF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tabrizicola oligotrophica|TrEMBL
MAQPRISFEFFPPQSLDASFKLFETVQALAPMSPEFVSVTYGAGGTTRKLTHDAVGTIHR
NYGLNVAAHLTCVEASKSETLEIAEAYHAAGVRQIVALRGDAPNGADRFAPHRDGFAHSA
DLVEALARTGKFEIAVGAYPEPHPDAADPTADVRWLKRKVDAGANKAITQFFFDADTFFR
FRDDCVAAGIHAPIIPGILPIQSWAGAKRFAARCGTKVPAKLDEAFTTAARDGREELLAL
AQCTALCDRLIEGGVEDLHFYTLNRPNLTREVVRALGITPQVQLEKVA
>A0A6P2PYS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia metallica|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRTTRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATRTICERLDG
>A0A388T9T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Termititenax aidoneus|TrEMBL
MRLTEIYQQPPPIISLEISPPKTDDGLASLLTELKKLKQLNPSLISLTYGAGGTTQGRSL
LLLEKIRRELNLELMTHLTCIGSSEKSILAFLQKVSGWGIENILALRGDWPRDNPGYQPE
SDTFKHAADLIRFVKKNTALSVAAAGFPEKHPEAENLQTGLKHLEEKTAAGAEVVFTQLF
FDNQYYYDYVKSARTAGIDTPIIPGIWTITNLKQIQRVAELSCAKIPAELLARLEKAGKQ
EVREIGIDYAATQIRDLLKHGAPGVHLYTLNKADAVSAVLRKL
>A0A5N7JRN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas kitaguniensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
NEAKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLHNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>R9AV96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 110321|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKTVHQELQRLNPEFFSITYGAGGSTRERTLAAISDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDGDLQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERITKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A497ZV66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. M71_S20|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTTQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGDPGGDWVRHPEGVLYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTEHFVR
KCQAGADFAITQMFFDADDYLRLRDRVAATGCDTPILAGVMPVTQIGTIERSTQLSGAPF
PPALADQFAKVADDPEAVRRLGVEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLQ
VAARM
>A0A417KNP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. TM10-16AC|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTNSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>A0A7C7XMR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MKSMIEDGLVHIFDGAMGSVLYTRGVFVNICFDELNLSNPEIVRRIHQEYVSAGSEILET
NTFGANPVKLSSHSLGDRTEEINEKAARLARDAGAGQVAVVGAIGPLGIRIEPWGPTARA
EATAFFERQVNGLLAGGVDGFILETFADLNEIDCAFTAVRKLGDLPVIAQMTLGQNGKTV
YGHTASQIAQELTSIGVDIIGLNCSVGPAVMLDAIEDMADTTSVPLSAQPNAGLPRTVRD
RKIYMATPEYMAQYARRMVDAGVRFVGGCCGTTPDHIKQIRDSVRSDQPNRVMVRVTDVD
REGSATLDPVPLEACSAWGRKLSRGEPVVSVEVLPPRGWDRNAIVEPAHELKDAGVDSLA
IVDGPRSRSRMGALSAAVIVEQEVGIEAIVHYTCRDRNMLGMISDLLGAAAVGIRNLLVV
SGDPSVHGPYPDMTEVFDIDSIGLTNVVTGLNQGVDPAGNSIGDPTKFVQGVVANPGALD
LEREVTRFRYKVEAGASFVVTQPIFNPESLERFLDKIHQWKIPVVAGIWPFLNLRNAEFL
ANEVPGATVPEQIIDRMRKAQISGDEEALNEGIEIAAEMIDAVRPLVQGFHLSAPSRRVD
VALRVLHEAGVSTNT
>A0A7X4J8R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MADLREMLSGGRVHVMDGAMGTMLYARGVFFNVCYDELNATHPDLVEDVHEQYIRAGADI
IETNTFGANPVKLSSHGLDARTEELNERAAAIAVRAASGRAAVAGAVGPLGIRLEPLGPT
SLEEARDYFGRQVDGLLAGGAAGFVLETFSDLVELEQAFRAVRSRCDLPVIAQVTVGEDG
VTAYGTTVEQAARAAEAWGAEAVGLNCSVGPAVILEGLEAMAQVTRLPLAAVPNAGLPRA
IGDRKIYVTEPEYMAQYARPAIDAGARIVGGCCGTTPEHIRGIAEVVATIQPQSTSIRVI
RSVGESSARKTPPPLASRSELGRRLAAGEFVTMARVLPPRGWDTARMLDDCRALAQAGAD
VIGIHEDRRTARLSVLVLAGLIARSCPAEPLAHYTCRDRTLFGMISDLLGTAASGVRNVL
LLTGDPPGAAPYSDFRSVVDVDSIGLTNVVTAMNSGVDPSGNDIGPPPGFVVGVALRQGT
RDPARELGRFHWKVDAGAHFAVTQPVFDAEHLVEFLAGIGDGGSGPGIPVVAAIQPLGSL
RHADFLKNEVPGVVLPDRVLERMRRAESLSADHATAEGIAISRETAEALAGEAAGLEVAA
HRGPGLGAAVAVLEGMAVV
>A0A7C7HZM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
HLARDAGAGRVAIVGAIGPLGIRIEPWGPTARAEATAFFERQVNGLLAGGVDGFILETFA
DLNEIDCAFTAVRKLGDLPVIAQMTLGQNGKTVYGHTASQIAQELTSIGADVIGLNCSVG
PAVMLDAIEDMADTTSVPLSAQPNAGLPRTVRDRKIYMATPEYMAQYARRMVDAGARFVG
GCCGTTPDHIKQIRDLVRSDQPRPVMVRVTDVDQERSATLDPVPLEACSAWGRKLSRGEP
VVSVEVLPPRGWDRNAIVEPAHELKDAGVDSLAIVDGPRSRSRMGALSAAVIVEQEVGIE
AIVHYTCRDRNMLGMISDLLGAAAAGIRNLLVVSGDPSVHGPYPDMTEVFDIDSIGLTNV
VTGLNQGLDPAGNSIGDPTKFVQGVVANPGALDLEREVTRFRYKVEAGASFVVTQPIFNP
ESLEEFLDKIHQWKIPVVAGIWPFLNLRNAEFLANEVPGATVPEKIVDRMRKAQISGDEE
ALNEGVEIAAEMIDAVRPLVQGFHLSAPSRRVDVALRVLREAGVSTNT
>A0A7X3UXL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MADLREMLAGERVHVMDGAMGTMIYTRGVFLNVCYDELNDTHPDLVEGVHEQYIRAGAEI
IETNTFGANPVKLSSHGLDERTEELNALAAGIAVRTASGRAAVAGAIGPLGVRLEPLGPT
SLEEARDYFGRQVDGLLAGGVDGFVLETFADLVELRQAFRAVRARCDLPVIAQVTVGEDG
VTEYGTTAEQAARAAEAWGADAVGLNCSVGPAVILEGLERMAEVTRLPLAAVPNAGVPRA
VGDRKIYVSEPGYMAQYARRAIDAGARIVGGCCGTTPEHIRSIADAVGAIQPQRTSVRVV
RSVGEPTARKSPPPLASRSELGRLLARDEFVTMVRVLPPRGWDTSRMLNDCRALAEAGAD
VIGIHEDRRTARLSVLALAGLIGTSCTAEPLAHYTCRDRTLFGMISDLLGAAASGVRNVL
LLTGDPPGAAPYPDYRSVVDVDSIGLTNVVTAMNRGVDPSGNDIGPPPGFVVGVALRQGT
RDPARELGRFRWKVDAGAHFAVTQPVFDAEHLLEFLAGIGDGGRGPGDGGGGPGDGGGGP
GIPVVAAIQPLGSLRHAEFLKHEVPGVVLPDRVVERMRRADGRGAEHAAAEGIAIARETV
AALAGKVAGVE
>A0A8D1ERZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MDRPKAKCLPAGQCCPSLGVWALEAGISRSSVPPAISRSSAMVNEPRGNGGPGPRCEGSS
SGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEVTG
YLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACSEMGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKVGASLGHRVRGRHIYA
TIRQSRSAPPIQALCQTDTQTEPGPCPLRAPSLAREAIRG
>A0A2V7GP56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYAKGFFLNVCYDELSVKQPRLVREVHEEYVRAGAEILETNTFGANPLKLASFGLA
DDTEKINRAGAELARGAAGARASVVGAIGPLGIRIEPFGPTSQGEAEALFARQARGLLAG
GVDGFILETFSDLSEIHAALRAVRSAGDLPVVCQMTIGTDGLTYYGTDPETFTKELTAWG
ADVIGVNCSVGPAGVLEAVERMVKVTDRPISGQPNAGLPRDVGDRKIYLASPEYMASYAR
RMIEAGARFVGGCCGSTPEHIKKIRDYVASVVPRQASVVVPRAQVQAPAGVTPAPLVAKS
RWGAKLARGELVTSVEIVPPKGVDPAPMLAQSRALKAAGVDAVNVPDGPRAQSRMGVLPS
AIMIEREVEIETVIHYCCRDRNLLGMLSDIIGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLTNLVYRLNQGLDPGNNPIGGATKWVIGVGVNPGAIDLDRELSRFAWKVDAGA
EFAVTQPVFDQRQLEAFLKRVEQFRIPIVAGIWPLVSLRNAEFLANEVPGVNVPDEVLQR
MRKATDKGKEAALAEGVAIAREMFARVKAVVQGVQVSAPFGKVGVALEVFKA
>A0A7V5T7V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
FGVPILVGILPLKSARHAEFLHHEVPGITIPDAVRERLRRAQEDEAAEGMRIARELIAQL
RPHVAGVHLIPPSERWDALPDVLAACLPQQLKTDALGA
>A0A7V6KRQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacteriaceae bacterium|TrEMBL
MKIKKLFKEKNLVYSFEIFPPKEDLPLEKVFNTIEKLSELKPDYISVTYGAGGSTLNNRT
SLLSSRIKNNYGIESLAHLTCIGAKRGSIDKILDELKENNVDNILALRGDIPQGGFVSGD
FINSQDLISHINTKGNFGIGAACYPEGHIETKVKDLDIDILKFKEEAGADYFISQLFFDN
NLFYNFLNKVKKKDIKSPIQAGIMPVINKRQIERIVSMCGATLPRKFIRILNKYQHDSIA
LRDAGIAYATEQIVDLITYGVEGIHLYTMNNTTIANNITENISSLIQSINSKKVI
>A0A2E7JHQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MSLTTPHQPQRYSXAWXKKPLRHLLEETDEFVHIVELVTSRGLXTESDGRKVMGXARRLA
EHPAFHALSITDNPGGNAMISPDILGTDLISRGQDCIIHIACKDWNRNAIQGRAWQLASE
GFDNILALSGDYPISGYEGTAGAVFDLDSVGLIEMFTDMNSGLKVXRGKKTRRMAKTAFY
LGVAINNHKRYEREVMPQYFKLAKKIRAGAHFAVSQIGYXARKQDELLKYMALHDLAVPA
IAXVYVLSAPAARFFHKGNIPGVEVTDELMAVVEERAKADDKGKAFFIELAARQCAIARG
LGYRGAYLGGHLQYGDYEKVXELSTSYGADDWRDFAKELHFSFADEFYYFEPEEGTGLSS
TEVNRAYVASREKAARREARADLPLSYKFNRLVHDXVFAEESAGFRLGARLAAALAQRPK
AEKMFHRAEHAMKIVSFDCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTRQGKCEIGE
KECIWARAYDRLKAYGEEEHMLDGPAVIKNAGLKGTSAWLNTFSHKDHHGKRKEQK
>A0A0D5NSI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus beijingensis|TrEMBL
MKPDLREVLRTSILTGDGAMGTYLYQMGFPIGVSYEEINMVRPDVIQNVHRQYYEAGARI
IETNTFSANEEKLSKYGLESEADAINRAGVRIARAAVGDDAYVVGAVGSIRAGKRKNLRT
ASVEQALQRQIYALLDEGADGILLETFYDLEEMQLALRIVRSLGKAPAICQFAVDELGRT
QDGYSLADAFSRLEQEGADVVGLNCRSGPSGILRAVDTIEGPLPLPLSIFPNAGIPDYVD
GKYMYTATPEYFADMARKFADRGARIIGGCCGTTPEHVAAMAAALRDYVPQSGGPAASAG
IRDEVARRGPDTAAARSAAQDAAAGAAPAEALIVPQQPATDERGAESANAGVTTDPEAGG
DSPSRTPSIISLVRQRHTVIVELDPPRDLDIRKFMEGAAALKEAGVDAVTMADNSLAVTR
MSNLALAALVQERIGLRPLVHIACRDRNLIGTQSHMMGLDALGIDHVLAVTGDPARFGDL
PDSSSVYDLTSFEMIRMIKQLNEGIAFSGKPLKQKADFVVGAAFNPNVKHLDKAVKRLER
KIDSGADYIMTQPVYDPELIVQVAEATAHLNVPIFIGVMPLASGRNAEYLHNEVPGIQLS
DEVRRRMAGLEGAEGRSEGVRIAKELLDAALPHFNGIYIMTPFMFYDMAAQLTAYVWQHT
ERIV
>F7WYX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MHDKIFNLIECKKDVINLKNKIQISFEFFPPKNTAIDLLFINSIRKLKSFNPNFFSVTHS
VNTLNKNDTFMIVQKIRKMFTEITVAPHLTSIGYTTTDLRNIAIKYWAKGIKNIVALRGD
IPLNYRGDKIYAVDLIKQLKYIADFNIFVAAYPEIHPEAVSSKHDLINLKNKMDVGAEHA
ITQFFFSIEKFLRFRDNCHKNHIYIDIIPGILPILDIQQLKKFSNMTNVYIPKYILDIFN
KNIMDKKNVH
>A0A5C4V5Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sedi|TrEMBL
MALGIPSTMSGRAATVRDLLAAGERSFSFEFSPPKTEQGEKTLWNAIRRVEAVAPTFVSV
TYGAGGSSRERTVRATERIATETTLTPVAHLTAVQHSVAELRNIVGQYADAGIRNMLALR
GDPPGDPMAEWVRHPEGVSYAAELVRLIKESGDFCVGVAAFPEMHPRSLDWESDVRYFVE
KCRAGADFAITQMFFHAEDYLRLRDRVAAAGCATPIIPEIMPITNARQIDRFQQLSNTSV
PPDLKRRILAVKDDPMAVRSVGIEFATELCARLMGEDIPGLHFITLNTSSHSTATLDVYK
NLGLHQRS
>A0A4C2E9S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygosaccharomyces mellis|TrEMBL
MRISEKLQSHRSKSTKPTFSFEYFVPKTTQGVQNLYDRMDRMYQSTLPQFIDITWNAGGG
VLSQLTTDLVETSQSVLGLETCMHLTCTNMPVSQIDDALESARLSGCQNILALRGDPPVN
QDSWKPVEGGFQYAKDLVKYIRDRYGDYFDIGVAGYPEGHPETVGNDDTLLDHLKEKVDA
GANFIITQMFYDGDLFIKWCQRVRAKGIDVPLIPGIMPITTYAAFLRRANWCDVHIPQEY
FDKLDPIRDDDQLVREVGTDLVISLCRKLLDSGYVSHLHIYTMNLEKAPQMILDRMELLP
KHDEPLDNHLAILPWRKSLNPQRRNEEVRPIFWQRRPYSYVARTSQWSVDEFPNGRFGDS
SSPAFGDLDLCGASLIRQSGKRSLELWSTPSSMQDIAQLVINYLSGGLQYLPWSDTPLNH
EVDDILPELVSLNQKLIVTVNSQPQLNGVKSSHPVHGWGPRDGYVYQKMYLEFLLPKEKL
PKLHDYLVNDVMLTYFAVDHDGNLTTNHHDGTKANAVTWGVFPGREVLQPTIVEKVSFLA
WKEEFYHICEEWKLNFINNNCDQSVKLLQHLIDDYVLVNIVDNDFISPENRIFNLLSSI
>A0A4Q5EZB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. aa_0143|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVQLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAEI
>A0A3C0ZX99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sarcina sp|TrEMBL
MKIIDILNQKKVTLSFEVFPPKTEEALLSVEKATEIIAALRPDFMSVTYGAGGGTSKHTT
RIAADLEKKYGTNVLAHLTCVSSTKETVRKMIDTYKEHGIRNIMALRGDIPAEGRSVFDY
NYASELIYDIKSHDGDFCIGGACYPEGHVESASQAEDIRHLKEKVDA
>A0A2K5XYC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mandrillus leucophaeus|TrEMBL
MDHRKARVLPAGHYCPSLGIWASQAGSVRFSVAPSISRNLAMVNEARGNGSLNPCLEGSA
SSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDTVVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVLEDALELLNRPTQNERETEAP
>A0A1N6GDI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vannielia litorea|TrEMBL
MIVLRVMSLFHIPRNATTKTDPMPMRADMPATPSVSFEFFPPQNLEASFRLWDTVQVLAP
LDPTFVSVTYGAGGTTRELTREAVATLHKSSGLNVAAHLTCVDATREETLGIARAFHEAG
VREIVALRGDPPKGSKGFEPHPEGFANSCELISALKATGDFKIRVGAYPDPHPEARGDGA
DVEWLKRKFEAGADEAITQFFFEAETFLRFRDACVKAGIDKPVIPGVLPIENFRNTARFA
ARCGAKVPQWMAEAFATAERDGREELLATALATELCTELLEEGVDHLHFYTLNRPGLTRD
VCRALGVHPVQTLENVA
>A0A532T9X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon Loki_b32|TrEMBL
MAEKKVYSKLGEMLANGEFILTGELEPEKTCDLSHTIQEAKEIAPYVVAANVTDSPLGIV
TINSMAASHIIQKEAGLEVIWQLTVRDVNKLGIAGMIMGGHALGLRNVLSLTGDHPALGD
MPESKPVFDLDSATLIRLVKDMVDKGTINGHEIENPPTLHVGAAANPNSDPMGAEILKIG
RKAEAGCEFIQTQVVYDLDRTIEFLSEIKKYNVPILLGIFPMKSYGMAKGFDTFVPGVDV
PKDILAKWKSIKTEFKDDKKEQKRLYDQANYEFFKPFISELKKKGLLAGVHCMAVHYPRI
FPKLMEVIKA
>A0A533SHP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MDFLERLHEQVLVGDGAIGTMLHARGVTAESGFERLNLTNPELVLALHADYIAAGAQVIE
TNTFAANRLRLQQLGPDDAVRQINLQGAVLARKAAAGKEIFVAGSIGPLPRFRGESEAPA
SEEISDIFREQAFALAEGGVDLLILETFADLQQLKLALAAAAETGLPLIASMAFLERGRI
SGGLGVEAVALELATAGAHCLGANCGAGTLEMTRNIQRMAAVTLLPLVAYPNSGFPEYVD
GRYIYRSTPEYFAARGLETARAGANLVGGCCGTTPEHIRLLAAALHGMKPAARTIVPPAP
TSRITVSASPSQTGFLANWGRRTVITVELDPPKGLDCGKILEGCRVLRDAGADAINIAEN
PLSRVRLGNIALGELIQREVGIEVIVHVTCRDRNLIGLQSELMGASLLGIRSILAVTGDP
ASMGEQSGASSVFDLNSLGLIALLHDLNAGLNGTGNSIDRGTGFTIGAAFNPNVRNMEAQ
VARLEKKLANGAQFVQTQPLFDLERLDTMLQLTGKLPIPILPGILPLVSERNSEFLHNEV
PGITIPDEIRTRMRGKGKEEGLREGLAIAREFIDAARSRVGGFYLMPPFGNYRIAAELVR
YIRQEE
>A0A7C1GXQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKVIEHLQNPSYPHFSFEIIPPMRGKSGQVILGMVEVLKFYSPPFIDVTSHAAVANYEEL
DSGVIKRRVRRKRPGTIGICGVIQNRFGIDTVAHLLCRGFTQEETEDALIELQFLGIENV
FAIRGDDTNYKKPVDPNRRENDFASDLVKQIHNLKNGIYVEEILNAEPLQFCIGVAGYPE
KHFEAPNLKIDILNLKKKLDAGADYIVTQMFFDNNKYFRFVEICREACIEAPIIPGIKIL
HNAKQICSIPKNFHVELPEELSDELLAEQKHAGEIGFHWALQQCRQLLERGEKHIHFYVM
NDADSVAKLIKAL
>A0A7K1LBP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura litoris|TrEMBL
MRRLRPDRPPTVRELLASGRSFSFEFFPPKTEKGARNLWRTIRELEPLHPSFVSVTYGAG
GGTRDKTVDIVERIATDTTLTPVAHFTAVDHSQAELRQLIGRFAAVGVRNILAVRGDPPG
DPMGEWVKHPDGVEYAADLVRMIRSYGDFSVGVAAFPYKHPRSPDIESDTRHFVAKCRAG
ADYAITQMFFRADDFLRLRDRVDAAGCDVPIIPGIMPVTQISTIDRSEQLSGAPFPADVR
ARFEAVADDPEAVRRLGIEHAAQLCRDLLDQGVPGIHFITFNKSTATREVYGLLEADGYG
ARGSVPPMTA
>A0A7J3B0C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Korarchaeota archaeon|TrEMBL
MEIGIEIVPSNLPKFLRSLSSVIGHANFISLPECPFGRPLPSPLILSVVAKGLGLEVIPN
YRVMDRSELGFISEIMALSEVGIRRVVIVRGDLPSIGMPTSLNPVRAIELIKEHGIDIEV
GVATYTKPNEALRAKIEVGADFVVTQPIQDVGELSELLDFLGDIPLYTMIMPGMEDLDLN
VLREMGLNEVRNVDYKALLQDISRTKVRGVIISSPKGVSKALEILR
>A0A4Q4J9M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium indicum|TrEMBL
MTLGFPSVEAAQAWQAPLYADLAGDVNVSFEFFPPKSEKMEEQLWSAIQTLTPLAPKFVS
VTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKAEIDEVADAYWEAGVRHIVAL
RGDPPEMGAKFEPHPEGYKGAAELVEGLRKRHPFEISVAAYPETHPDAQSAQSDIDNLKR
KLDAGATRAITQFFFEPDTFFRFRDTVAAAGIDADIIPGIMPVSNFAAVQRMSAMCNTDV
PGWMGKLFEGLDDHAAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVATNAV
>A0A7C4FQK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKIGDILRNKKESISFEFFPPKTDSAERTLFETIEKLSAFDPTYVSMTYGAGGSTRDKTI
RMVERLVHETRLTVMPHLTCINASKDDTRGILDYYKKLGIENILALRGDPPMGVTELPEI
EDGFDYARDLIRFIKKEYDFSISAAVYPEKHREAPSIEMDMAYTKEKVDLGAEFLITQMF
FDNKFFYDFMDRCEKIGINVPVIPGMMIITDLKKIGQLSNMCGTSIPSKLGKLMEKYDEP
TDDARKAGMEFTINQCQDLLDNGVKYLHFYTLNRWEPVTEVLNSIH
>A0A7W0F9X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MSGKDLAGNELEGDAPDFCLGCVVNPGADPLEPQLLKLEKKIKAGAQFVQTQAVYEPDKF
AFFIDRVRKEVGDIPIMAGIVLLKSAGMAKFMNKNVAGVHVPDEFIEEMTFPKGTPVEEK
KAKSVEIGIRLVKELKPLCQGIHFMPLGWDDCAAGIIAKSDLS
>A0A2A4RMR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MLKGSGTTFSFEFFPPKSATGAEKLFDHIVKLEHLGPAFVSVTYGAGGSTRQLTRDLVHK
VREKTGIVTVPHLTCVNHSEDEIRTIVEGYAQRGIQSILALRGDAPADEMHDWGSDRFSN
ASELVYFIREISDQYKGKNDFPGFGIGVAGFPEGHPGTPNRLNEMDYLKAKVDAGADYII
TQMFFDNRDLYDFRDRCEMSGIRIPIISGIMPIQSVSGMKRMSELAQGMRFPAPLMRMVR
RTDGSNDAIRRVGLHWATEQCRDLLDHRVAGIHFYTLNTSSATLEIYKTLGAENSDQLGN
GAMLDF
>A0A2G4J3V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MTSSVAPVFSLEFFPPRDDAAKQRLVAGAKQMLVIDPHYCSVTFGAGGSTRDGTLDTVRV
LREMGREAAPHLSCIGSSRDELKALLQLYRQEGVRRIVALRGDMPSGMGADAAGALRHAS
DLVELIRQETGDWFHIEVAAYPEMHPQAAGPEHDLAHFVNKVHAGADSAITQYFFNADSY
FDFVDRAQAKGVNIPIVPGIMPITNYTQLMRFSEMCGAEVPRWIRLRLSEMGDDKESIRA
FGTEVVTDLCETLLDNDVPGLHFYTLNNAEATLAIWRELMD
>A0A0L6VW39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. WF1|TrEMBL
METPNISIEFFPPKTPEGAEKLRVARQKLAQLQPKYFSVTFGAGGSTQQGTLDTVLEIQS
EGHAAAPHLSCVGGTRESIRTILREFQAKNIHRLVALRGDLPSGYGGAGELRYASDLVEF
IRLETGDWFHIEVAAYPEMHPQAKSPQDDLQNFVRKVQAGANAAITQYFYNPDAYFQFVD
NARKLGVDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWIRLKLASFGDDSASIKAFGLDV
VSQLCERLIAGGAPGLHFYSMNQAAATTAIWQRLHGTPAA
>A0A0P9SGP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. lapsa|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRKLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A069IF10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp. SK-3|TrEMBL
MQDRYFSFEFFPPKTAEGAEKLRNTRAQLAPLHPKFISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIREILKTYRDGGIRHIVALRGDMPSGMGEIGEFRFANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLENFERKVKAGADSAITQYFFNADAYFRFVD
DVRAMGVEVPIVPGIMPITNSSQLMRFSEMCGAEVPRWVAKRLEGFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNTASATKAIWQRLKL
>Q1AVP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129 / PRD-1)|TrEMBL
MDRVVADLLQHIRYEVIPLAGTEEAVERWLISRRAEEQKKTTITITASPTRGIEPTIALT
ERLGAKARRRGGEPSSLCVVPHLSARLIEDEHHLEEIVARLKEAGVEEVFVIGGDAKEPR
GRFHDALGLLEALEELGRPFERVGIAGYPEGHPSIERAELERALRKKALYASYVVSQLCF
EAKKVLLWARRVRELGVGLPVVVGVAAPIDPKRLAGVAAKIGIGDSARFLRKQRAKSLLR
LLSPGRRRSALSLVYEPGGFLEELVEEGSREGFFASSGGTDEGGGMISGLHLYTFNDLQR
TLEWVREEKRSRG
>X5ZKM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNJC395A00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITERQVDMVK
TAH
>A0A2E0BZU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MNLYKGQRKIQLKLKSALMINSNLNNSTIQKSFEIVPPRYSISDSFINKXXKYEKSFDLL
DITCCPMATLRVNPIAVAHRLILKGXKPEKLIVNFSSRDRNSLALQSEIFGALSIXLKNI
LXVRGDPITYGNSKNSKEVFELTTDQIINKVXNINKGLDFNNNXTNSKFYINIFSTLNIN
RSFNEIKKTIQNRLRKGSKFFITQPIYSESDFEKIIKLSKSKXYKIFAGILPVKNKKILG
NLLKKLGGITIDSPHLVELANYDDKKIHSHSSKHLKELIKVYKKNLDGLHXMTSGSINEA
SNLIKDL
>A0A2G0WP70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ICMP 564|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAAQLASYQPDFFSCTYGAGGSTRDRTINTVLQLE
SQVNIPAAPHLSCVGDSKADLRGLLTQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANSGANSAITQYFFNADSYFY
FVERVRALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>K9ZCH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabaena cylindrica (strain ATCC 27899 / PCC 7122)|TrEMBL
MPDTQSFSVLNNFRKAVAAGEFLVTAEVAPPKGGDPTQMLKMAATLKGRVHAVNITDGSR
AVMRMSSLVASAILLQNGIEPICQVACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPEAKAVFDLEAVRLLQLIRKMNQGIDFNEKILNDGALDLFAGAAVDPQSKSWSGLQS
RFEKKVEAGAQFFQSQLITDFEILEKFMDKIAAGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPQHIIDRLAKAKDPLEEGIKIAAEQVQIARELCQGVHMMAVKREDAIAPILDLAGV
EKVS
>A0A090F204|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. ORS 3324|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTITRLEPLKPQFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIREFAGFGVKRFVALRGDPAEGVGT
AYRPHPDGYANGAELVGAMKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALLPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHESEAA
GSAAA
>A0A2M9CD27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sediminihabitans luteus|TrEMBL
MSVADVVAAGVARTRPTISFELMPPRNPAAAPKFWDTASRLVAARPDFISVTYGAAGNDR
DTARTVVGHLIKSTPVLPIAHLTCVGASRDDVSEVISDFLDEGVRSFLALRGDPPKDQPD
WLPAEGSVASSIELVDLLREVEAHRCAASASTALRGAARPLTICVATFPDGNRDAGTTRA
QEVTRLLEKQHAGADFAITQLFYEASSYTDFVTEARDAGVTIPILAGILPMTEPRRLHRV
EELTGVPAPREVVAALEAAPDDDARHALGIDRTVALAQEVLDAGAPGLHVYTFNKYQAAL
DLLEGVHLGGGTRVPDLASGPWVSGSTTTTEGHIA
>A0A7W6CM88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sediminicola|TrEMBL
MNASYEALNEARKALDAPLFAGLPGDIRVSFEFFPPKSDAMMAQLWEVVETLAPLDPAFV
SVTYGAGGTTRDRTHGTVARIISEARLPAAAHLTCVDATKAEVNAVAEAYWEAGVRHIVA
LRGDMGQPGAPFVPHPEGYQNAADLVAGLKRVAPFEISVAAYPEKHPDSADVDADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDRLAAAGIDAPVLPGILPVSNFAQTRKFADACGAA
IPAWMEGLFAGLDTHPPARALVAATIAAEFCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GVRPNPARVAQVKAA
>A0A537G2I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MGCDFRETHQHRQRCRTRKGGFHLRLSDAANNHPIVTVELIPDRVIPAHLPILQGRVDAI
TIPALRNGEDDPSYPAGFRVTPQTRSLASAVIVRKTGAEAVPSLTCRDFRRSDLALVPSL
FKKGLDNFLVVFGDPYPGQRIEDYDFRKTEDLIRGVLSVFDGQRPCIGAVTNQYAEDQER
ETSRTLRKVDAGADYVVTNTAFDDDLVLRHVDRLRSRGLKAPIFVQVSIPSGLKNLLFVS
QKFGIPVPEKVRQTLSRNPIGGGIRIAADAYTVLRSEVNGIHFSYLHRSHNPIPAYTHLL
DAIQTDGQLTVSIQAALRH
>A0A537I6T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MGQPRLRTENQDLGGDSCEAHQHCQGRRARQGGDPVRLSDAANSHRIVTVELIPNRVIPA
HLPILQGRVDAITIPALRNGENDLSYPTGFRVTPQTRSLASAVIVRKTGAEAVPSLTCRD
FRRSDLALVRSLFKKGLDNFLVVFGDPYPGHRIEDYDFRKTEDLIRAVLSTFDGQHPCIG
AVTNQYAEDQERETWRTLRKVDAGADYIVTNTAFDDESVLDHVDKLRSQGLRVPIFVQVS
IPSGLKNLLFVSQKFGIPVPERVRQILSRNPFGGGIRIAAEAYTALRTEVNGIHFSYLHR
SHNPIPAYTHLLDTIETDGQLTVSIQAALRH
>A0A8G0RC97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium scindens (strain JCM 10418 / VPI 12708)|TrEMBL
MKIRDILKDNSPHVSFEVFPPKTDAGYEGVRAATEKIAALRPSFISVTYGAGGGTSRNTV
RIASQIKNDLGVTSLAHLTCVSSTKDEVRGVIGQLKEQGIENILALRGDIPADGEFPLPN
HYRYACELVEDIKSQGDFCIGAACYPEGHVEAAHKKDDIMNLKHKVDCGVDFLTTQMFFD
NNILYNFLYRIREKGITVPVLPGIMPVTSAKQMKRICDLSGTVLPERFRAILDRFGEDPD
AMKQAGIIYATDQIIDLIANGMNHIHIYSMNKPEVAEAIISNLSAIIKA
>A0A497ERQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Verstraetearchaeota archaeon|TrEMBL
MSSGRIFSNLMKELSEGKFVFTGELEPGKEGDIESTVEAARKLLGHVTACNVTDNPQSFG
YVDSLTAAYVVQTKTGMECICQLRCADKNRLALLSDVLAAGVLGIKNVLAITGDYVSLGD
AKGAKPVFDLDATLLTYMIRKVVDEGKDLQGNPIRNPPKLHVGVAANPGSAFLDMEVYKL
KRKVKAGAEFVQTQVVFSTEVIDRFFNKVKEVGVNIPILIGIFPAKSYAEAKFFHENVPG
VKVPEDYLNKLKEAKEIKDKEKKKERIDQINIEFFTKLLEHLKGTPAAGCHIMAVGYSEI
IPQLKKVVK
>A0A7C5MJJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MSKPAYSNLMKALNEGKFVVTGELEPLKTTDLSSIINAAKTIKEHVIAVNVTDNPTAFAY
TSPLVTCYLIQKETGLECVYQMTVRDRNRLAITSDLLAASILGIKNVLALSGDFVNVGDN
PQTKPVYDIDSTQLIYLIRKMVDEGVDLAGNKIINPPKFNVGGAANPNAVPLEVEVYKLL
RKQNVGVDFLQTQSVYDIERLKRFFELCDSIGIRVPILVGVTPIKGIKMLEWLSKFVPGI
HIPDEIQERLRK
>A0A209CSW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CS057|TrEMBL
MALGTPSTRTDHALTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A2E6USQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonadaceae bacterium|TrEMBL
MESQRKFTRTFSFEFFPPQTPMGVEKLRITRQQLARLNPKFFSVTFGAGGSTQNRTLETV
LEIQDEGYAEAAPHLSCIGSTSENIRSQLRTYSDRGISCLVALRGDIPSGMAQPGEFRYA
AELVEFIRKEFGNSFHIDVAAYPECHPQANSSQDDLLNFKRKIEAGANSAITQYFYNADA
YFKFIDACEIANINIPIVPGIMPINKFTSLARFSDACGAEIPRWLRKKMEGYGNDIASIR
AYGLDVVTDLCGQLLDSGAPGLHFYTMNSSDLTTIIWGRLGLQEEAKLTN
>A0A3M2GFT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium J007|TrEMBL
MTQQPLARSRFRLAVEAREFLVTAEVMPPKGSDASHTVEMARQLKDWVHAVNVTDGSRAV
LRMSPVATSAILLQHGIEPICQIACRDRNAIGIQGDLMGAHALGIRNILALTGDPIKAGD
HPKAKSVFELESVRLLKLIKKLNSGTDFNDNPLTDSPTDLFPGAAVDPQLKSWSGLKSRF
ERKLEAGAEFFQSQMICDFDRLDKFMNEIASGTDKPILAGIFLLKSAKNAAFINRCVPGV
HISDETIARLAEAKHPLREGMKIAAEQVQHARSICHGVHMMAVRREDLIPEILDMAGVSA
LTPQEAKIAV
>A0A2Z3UGV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium sp. 'caverna'|TrEMBL
MSDHRFELVCEIEPPTRPDLTRVRHQIGVLSAVADSFLIPDNHIGRATVSSVAVAHEVQA
MGARGIACLNSRDRNLLGLRRDLLTASAYGVERFLFVYGDKPTVGGRTSELTVRGMIEEA
RGTAEDPAFAGRRPFQVGVTSGLRPVPTWKSAADFVFVQVSYSVDALLRWRESVSLQVPV
YAGVMVLASAGMARNLAATIPDIDIPGQLVADVERDRNAGVDAACEQILAIRDSGAFDGV
HLVPVSRYREVAARLEREL
>A0A4R9XFY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.216.01.1.1|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAINPFAPPYDFRPYRLGKKIAAGAQFAQSQYCFDVPMFRAYMQKVRDLGYDEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEVTETQVDMVK
TAH
>A0A009SE97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 99063|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A4V1XZ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus sp. CRB-9-2|TrEMBL
MEKITDKIAALPADSNYFSLEFFPPKTAMGFANLRDRLDRMARALRPLFVNVTWGAGGST
AAKSLELAEICQRELSLTTCLHLTCTNMSRRMIDTALEDAKALGIRNILALRGDPPRAAE
YQDPNGEPEDAIDENFKWAIDLVRYIKKTHGDYFCIGVAAYPEGHADESHPRGQSLEHDL
PYLVEKTLAGADFIMTQLFFDAEAYDRFERTLREHPSGAFKTLPIIPGLMPIQSYQMIKR
TTKLSHAKIPDSISARLDAVKKDDEKVKNVGVDILSEIVERVKEIKSRTPGPKGFHFYTL
NLEKAVSFILERTNLIPPSTPEEDEAVADGLASRVPKLEINGSTHELPMPTKHRQRRESI
ARSDVEASIHELPMPAQDRVRRQSTIGSEPRNRVIVSEGSPSHPEYEATQAEASIIAEPI
NTRANTLAISEGEGTLGREATWDDFPNGRWGDARSPAYGEIDGYGPSLHVTNAQAITLWG
YPKKPEDINDLFVRHLKGELSAIPWSEEEFNAETATITNQLLALNSKGWWTVASQPAVNG
LPSSDPTFGWGPQQGFVFQKAFVEFFLPSAEWRVLLEKLQSAEVQDTVCWYAANAAGDFA
SSDLTGGLAGEAKEPSTNAVTWGVFPGKEIITPTIIEEVSFRAWSDEAFGIFAEWAKVYG
KGSESEALLEAVRADVWLVNIIHHDYIDTDALWNLLLN
>A0A2S6SC31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha5_Bin11|TrEMBL
MNENIANIKDLLQDYTIETTPKVYKKIEELKSLLPKKTWVYITYLPDEDPRNIIETAKKI
KEEGLEPIPHLPARTIENFHNLEKYIGSLSEISGVNKILIIGGSSSQKGNISSSIEVLRT
GLTEKFQFTDIGLAGHPEGSPDINNDELDKAIIDKNNFSKNTNANLFLVTQFFFEASSFI
TWEKHLNKLGNQLEIHAGLPGPANLKTLITFAKSCGIGNSLKFLSKQALNISKIASTNTP
DKIINDLSNYKKSNNYSKLSKIHFYPFGGMKRTSSWVNALINNDISINNDGEIKIDSFNF
>A0A1X8WMT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Canicola|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
STFFCEFYF
>A0A4Q4YKQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus sp. CRB-9-2|TrEMBL
MQIQEMIADAERTGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYFGLETCMHLTCTDMGEEKVNDALAKAYKAGCTNILALRGDPPREKEK
WVATEEKFQYARDLVAHIREKYGNHFGIGVAGYPEGCDDNKDEEQLLDHLKEKVDAGATF
IVTQMFYDADNFIRWMRKVRERGINVPILPGIMPIATYASFLRRANHMNCKIPESWMTAL
EPIKNDDAAVREVGKTLVAELCRKIMAAGIVHLHFYTMNLAQAARMVLEELDWLPTTTRP
RKQALPWKQSLGLGRREEDVRPIFWRNRNKSYVSRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKKWGEPKCIKDIATLFVRYIEKDLQTLPWSEAPLTAEADSIREDLIK
LNQRGLLTVNSQPAVNGVKSSHPVHGWGPPNGYVYQKAYLELLVPPELFPEIVSRIHSHP
DLTYYAVTRTGALKTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAYRLGKDW
AHCYDANSPSRVLIDKIMDEWYLVNIVNNDFHQPRTIFELLEGLHVDNLDVHNTPVSNGV
HNESNGDAGHTNGSGSVAAA
>A0A8H7RMA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor plumbeus|TrEMBL
MKIIEKIEQAQKSKHIAYSFEYFPPKTELGFANLIDRLGRMAQLEPEFISCTWGAGGSTH
ERTLELCTTAQSLYGLDTLMHLTCTNMEKAKIDEALEQAKKAGIRNILALRGDPPRGHEY
WTPVDSEFQHAIDLVKYIRKHYGDTFCIGVAGYPEGHIDCPDKNQDMQYLKEKVDAGADF
ILTQLFYDVDVCVTWMQKCRSHGIHVPIVPGIMPIPTYQSFRRMINLCNVKVPNNVMTDL
DAIKGDDQKVKEYGVNLAVEMIQKLYKEAGICNFHISTLNLERSTRLILEALHLHKDNGL
HVNKISPWAPIHDPAKAELWDEFPNGRYGDSRSPAYGENTYSSGQILPTSQAISKWGQPE
TEQDIAQLFVNYINGQVKSLPWCEESLHTESETIRQILTDINQRGYWTVSSQPAVNGASS
QDKIHGWGPKNGYVYQKAFIEFFVSDQQVGELLSRLGKDDSITYYATNQKGDFSTNVSDA
DAQNAVTWGVFPGKEIIQPTIIEKASFEAWKDEAFSLWTEWEEQYAPNSSSQKILKDIGN
RYWLVNVVHNDFQKPDLLFNVMLS
>A0A2N0YYT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niallia nealsonii|TrEMBL
MSFLTKMKNQILIADGAMGTLLYSYGKDSCLEELNLSHSSQIEKIHRAYIEAGADLIQTN
TYAANYLKLQRYGLEDSVKEINSAAVRIAKQAAKNSNAHILGTIGGNRGIKPQAITLEEI
KRSFREQLYCLLLEGVDGILLETFYDLEELKTVLSIAKKETNIPIIAQVSAHEIGYLQNR
IPIIEAFKELEQIGADVVGLNCRLGPHHMIASLKEVPLLKNAYLSAYPNASLPSYNDGVF
EYKDNAEYFRQSAVEFRNQGVRLLGGCCGTTPEHIKNFAESLKDCEPITEKTIAAKQADS
ITIAKKQRRDKEPLENIVKERPSVIVELDPPRKLDTKRFFEGAQKLKEAGIDAITLADNS
LASPRICNSALGSMTKNQIGIRPLIHIACRDRNMIGLQSHLMGLHTLGLNDILAITGDPA
RVGDFPGASSVYDMTSLDLISMIKQLNEGLSLSGKDLGEKTNFSVAAAFNPNVRQVDKAV
KRLEKKIEAGADYFITQPVYSEEKIIELYEATKHIKTPIYIGLMPLTSSNNAEFLHNEVP
GIKIADSIRNTMAQYKDNPVQAAREGIKITKSLIDVASQYFNGIYLITPFLRYELSVELA
LYTHEITGPLRRITT
>A0A7C2BPF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MGPSGSSSPRGQPQTGYRNRLAERLRRGAFALTVESPPLVGSKPLEQVLAEVLGLARWLE
QDGRVDALTVSDRVRTDRDHDPVLAAAQVVEATGSVPLVHWAGKGRTVRDLEADLERARS
WGLSSFLLLTGDALREPAPAGADRYLDSVDALRIARQRLPDSLLAAAVNPFKYREEALWG
QYVKAAKKLRAGADFLMTQIGWDPRKLAEVVRWLRARGFGAPVLATVWLLTPRVAARLLQ
GASLPGVYVPPDLLRCLESEAQSADHGRRQAIRRAALQVVGAMRLGLSGAHLCGVHTPRT
LEELLQTVEDLAKACPDLATWQAAWEEAMQHPDGRPVQLTPEGAYYLDGPPEGGASPSAS
ELRGFRFLGAVDRWVFDPASPASQALAGVLRRVDPAGPVGRLLRRAEGAIKGPWLGCQLC
GTCRLPHTFFVCPETCPKGLANGPCGGTDGNTCEFGDRECIHARIYRLARYTGELEAWES
TWVAPVPDAARGQCSWLLHYRGHGARTEVLPAASSPSSAGEPELSEVAT
>A0A7C6QIB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MVDCQLKQVISQMAESPQSSADNKALHTRRDELSLLPALEAGPLLADGAMGTLLLGRGIS
AEVCLEALNLSDRRLIEAVHREYISAGADIIGTNTYAANRCQLSSFGLEDKVWSINVWGA
KVARQAREVSGRPVLVAGSMGPLGRSLEPVGSLTKPEAEAAFREQAEALLAGGVDLFLIE
TMSDVEEAVAALAAVQAICRLPVVLQFTFTPEKATPAGQIPSRIMRRLNELEKKPAVVGV
NCGSGPQVLIEVLREMREASDFPCYWSILPNAGMPVKVGNRQSYQAIPDYFGRAVIHMIE
VGARLVGGCCGTTPAHIKAMRASLDHLLKEKQSAGTFPTPLPSSAAVQVMAPSPASSSSP
AVALSPAPPLVPEAHLEQPASPQSRFAARLAQGFVISVELDPPKGAVATKFIGAGRLLCE
AGVDAINVADSPMARVRMASLVGAHLLMKDVGVETIMHFTTRDRNLMGIQSDLLGAHSLG
IRNILALTGDSPTLGNVARATAVYDLDSIGLIHVLSGLNRGIDVAGNSIGEPTSFTIGCA
LSPNAENLEKELERFRRKLEAGAHFVMTQPLYELEPLYRVLDQLGGCPVPILLGLMPLYS
LKQAEYLHNEVPGISIPLHVRQELEKAGDDALRIGLEHAAGLVAEARPHIAGVYVVGSFG
KYEPIARFVRDLRSAGYI
>A0A6M0JXN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiorhodococcus minor|TrEMBL
MSTDTHRLPIYSVELFPPKTAEGMEKLKREIARINSVGPRYFSVTYGAGGSTRERTFETV
DWLCGQGIDTAPHLACIGSTRDEVRDILTRYRDQGIRRLVALRGDMPSGMGGGHGGDFRY
ANELVSFVRAEFGETFFIEVAAYPEYHPQSGSPARDLANFKRKVAAGADGAITQYFYNAD
AYFGFVETCLRAGLDLPIVPGIMPISNYTQLARFSDACGAEIPRWVRRRLEGYGDDVESI
RAFGHEVVLNLCRQLIDGGVPGLHFYTMNQSKPVLRLWEELGLPTPG
>A0A7W2MWT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. Urea-trap-16|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALSA
RGTTEIAPHMSCIGDDKSEIAELLEYYKTLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
YIREHSGDHFHIEVASYPEMHPQARSFEFDIDNLVNKYQAGANASITQFFYNADSYLYLR
DKLEKRGIDTVAQPLVAGIMPITNSSNLLRFADSCGADIPRYVRKQLTDFGDDRKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLTA
>A0A0Q9PEE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. Soil772|TrEMBL
MPAISFEFFPPKTDEQRTQLDRTAQVLKAHRPEYASVTFGAGGSTLSYTGDTVARLHTQH
GLSVAPHLSCMGGTRAEIAELLDGYRAAGYRRIVALRGDMPSGMATAGDFRYAAELVRFI
REHCGDHFHIEVAAYPETHPQADDALRDLQHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VRRLGVNVPIVPGIMPISNYSQLKRFSDMCGAEIPRWIAKRMQAHGDDADSVRALGAEVV
AQLCQRLLDGGAPGLHFYTLNRARATQAVLQQLS
>S5IHF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio parahaemolyticus O1:Kuk str. FDA_R31|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDATRSELIEIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRVAVEA
>I4B6Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H)|TrEMBL
MHIADVLKQNQPALSFEFFPPKTPEGAETLFQTISDLTPLEPAYVSVTYGAGGSTRQLTH
DLVVRLSRELGLTIVSHLTCVGASKDEIRLILERYAESGIHNIMALRGDPSKEAHGRWQQ
HPDGFAYAAELVAFIKKHFPQMGVGVAGFPEGHPETPNRLKEISYLKAKIDSGADYICTQ
LFFDNHDFYDYRERCALAGINVPIIAGIMPITSRKGMQRMAELSLGSRFPAKLLRALARA
EDDEYAENVGIHWASEQVRDLIDHGTAGIHFYTLNKSKATLKIYQSLGIKKSTALKT
>A0A5E4ZUI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea captiosa|TrEMBL
MSGSLDDKTIMTQPSFSFEFFPPKTADGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQG
TLDTVIEIQREGVDAAPHLSCVGSTRDNIRDILKTYRDNGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGDWFHIEVAAYPEYHPQAKSPRLDLEHFAHKVKAGANAAITQYFF
NADAYFRFIDDVSRLGVTVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
ESIRAFGLDVVSALCERLLKEGAPGLHFYTLNAASATKAMWQRLGL
>H8NV28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rahnella aquatilis HX2|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRQIARDYWDSGIRHIVALRGD
LPAGGGKPEMYATDLVHLLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPHWMNSQFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPDIAVPV
RA
>D4WHJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides ovatus SD CMC 3f|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A415E3Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emergencia timonensis|TrEMBL
MKLAELFNNRKTVFSFEVFPPKRDNPIETIYNTLDALQDLKPDFISVTYGASGSLADNST
CEIASAIKHRYGIESAAHLTCVNSTKEEVTQVLKKLHDNGVENILALRGDLVPDVEPKED
FKHASELITFIRESENEFGISGACYPEGHLDSRDQIEDILNLKKKVDAGAQHLISQLFFD
NNLFYDFLDKARIAGINVPIEAGIMPVVNKKQIERMVSLCGASLPAKFTKMMSRYETRPE
AMRDAGIAYAVNQIVDLVSQGVDGVHLYTMNNPYIAKRISESVKSLF
>T0VAX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris TIFN3|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYLDKTQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>A0A423UU60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces globisporus|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A2T2RNE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium QH_9_48_43|TrEMBL
MINRFRRAAQAKEFLVTAEVTPPKGGNPEHMLKMAQALKGRVHAVNITDGSRAVLRMSSL
AASTVLLQHGIEPICQMACRDRNRIGLQADLMGAHALGIRNILALTGDPVKAGDHTDTKA
VFDLESVRLLKLIGKLNRGFDFNDESLPDEPLDLFPGAAVDPQLKSWSGLKKRFERKHEA
GAQFFQSQMVTDFDRLGQFMNEVAVGTDKPVLAGIFLFKSAKNAQFINRYVPGVEIPEEV
IDRLAKAKEPLREGMQIAAEQVQIAQQLCQGVHMMAVKKEDLIPEILDLAGINPVDETKP
SAASETVPTR
>A0A1G4S8H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium C10|TrEMBL
MKITEYLKQHILITDGAMGTYYNKCYPLEGGLVEQAVLTDPKRIVRIHEEYIEAGAQLIR
TNSFAVNDLFFSDANQRNLIAKKSFRLAMEAVEASGKDVYVAADFGTLFHPVMQDLEQLL
SVVTSMVDAFYEVGARIFLFETQADTYGLDEIFTYIKEKDSENEIILTFSFDKNGYTKGG
LSFERILQQYGTDPKVDVYGVNCGMDPSHIKDLMEQTTFYSDKPWMVLPNAGYPYILRGQ
TLYRESADYFVSTMEKVLDLGANVVGGCCGSTPEYIRKMVERFGKRRPMPKDIGDIPTSM
TMEGRTLSSFWKKLGTGEKAFVVELDPPFNEDISKVMQGAKLLKEAKVDLLTLSDSPLGR
TRMDPMLLGAKIQKESGIFVMPHVACRDRNLISLRGMLLGSYVNDIRHFLMVTGDPVPAA
DRSHVTSVFDYNSIRFMNMAKMMNSDVFAKDTIVYGGALNYHGRNVEVIAKRMQLKMDQG
CSYFLTQPVYSQEDIQRVAQLKEMTGANIIAGIMPLVSYKNAIFMTNEMPGIHIPDEIVS
RYHPDMTREEAEDVAVSTSLDIARNIAGVCDGYYLMTPFNRVTLIVKIIDAIRDELA
>A0A848M352|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus lemnae|TrEMBL
MKPDLRKAWESRVLVGDGAMGTFLYQKGFPVGISYEELNLTAPEVIGDVHRQYIQAGAHV
LESNTFSANYDKLSKYGLEAKVEEINRAGVRIAREAAGQQGYVVGAVGSIRGGKRNNISS
EELKQHFEQQIHALLTEGVDGLLLETFYDVEEMLMALSIVRQASDLPVIAQFAVEDIART
LDGYTMVDAFRMVSQAGADVFGFNCRTGPNGMARALETLDGMRSLPASVYPNAGIADYVD
GEYRYGATPEYFGQMAVRFADMGARLIGGCCGTTPEHIAEISAALTDYKPAPLPSPEMTA
DRVVVHEHLDAVQEERKGEPTLADLAKERHTVIVELDPPRDLDITKFMKGAEALKRAGAD
ALTLADNSLAVTRMSNMALGHLVQSRVGLRPLIHIACRDRNMIGTQSHMMGFDALGIDHV
LAVTGDPAKFGDLPGASSVYDLTSFEIIRMIKQLNEGVAFSGKPLKQKANFVVGAAFNPN
VKHLDKAVQRLEKKIASGADYIMTQPVYDSELIVRMKEATKHLDIPIFVGIMPLASGRNA
EYLHNEVPGIQLSDEVRERMAGLEGEEGRKMGVQIGKELLDVAAEHFKGIYIMTPFMFYE
MSVQLTQYVWELSGRRESPLFH
>A0A7V3ZHU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyoglomus thermophilum|TrEMBL
MNFEERLKSGKFVITAEVSPPRGVDVSSFIEKTLLLKDRVDAVNVTDFQNVGVRITSLVG
SYLLLREGMEPIFQITARDRNRVAISGELLSAYTLGIRNVLVLTGDYTTTGIAKSAKPVF
DLDATNILVVAKRLEDGEDFSGKKLNKNPDFFLGAVFNPNLVPLEIEILKLLKKKKAGAE
FFQTQLFFDLSVMERVRERVGNEIKIIAGVTIFKSIEMLEYMMSSVPGIKIPTEILDMFR
NTKDIKSLSIEFCAEFCSKLKESKLLDGIHFLASRPSDIIKVLDLLNW
>A0A537JX29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrabacteria group bacterium ANGP1|TrEMBL
MTSPQHPFRARLARGPLLCDGAMGTFLYERGVPYDRCFDALNLTDRERVLNVHLDYLRAG
AEMIETNTFGANAMKLEAHGLADRVRDINWHGAKIAKEARDIIGRAVWIAGSIGPLGKPL
VPYGRVTREEAGGAFRAQIDGLVEGGADVLILETFTDLEELLEAVRAARAACDLPVIAQM
SFTEDGRTRYGHGPAEVASALEAAGVDVIGANCSVGPVPMLDVIQQMAAHTRTPLSAQPN
AGFPTLLEGRYLYMSSPEHMAIYARKMVEAGAVIIGGCCGTTPVHIAAIGRAIQALRPAA
VRTPAAVPEGRGEPVAPPVDQPTQLAQKLGRRFVISVEVDPPKGLDATKDLEGARLLREA
GADVIDVGDSPIGRVRMGALAMCVLIQQEVGIETIIHFTTRDRNLMGVQADLIGAHALGV
RNILALTGEPPRGDYPNVTAVFDVDSAGLVRIIKQFNGGLDLSGKSIGRPAQFLIGCALD
MNPETLDRELPKLERKLEAGANFFMTQPIYEPETLDGFERRVGRLPVPVLLGILPLQSFR
HAEFLHNEVPGISIPQWVRDRMQAAGNAGREEGLRLARELLEALLGRIDGAYFMPSFGRY
ELVATLVGELKARIGAGAVRTRA
>A0A8H7DT60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pleurotus ostreatus|TrEMBL
MKISQKIQQSTKEGKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQSMIGVETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPQGKDE
WEAVEDGFVHGIDLVKHIRRIYGDYFDIAVAGFPQHMLLPPDELAFEMKCLKEKIEAGVN
FIFTQMFYDVEIFIEWVKAVRAAGITIPIVPGIAPIQTWNGFVRATSLAKTIIPQSFTEA
LEPYKNDDEKVRAIGTRLVADMCRRILDEDLGIRGLHFYTMNLEKATKMLLEELNLVPRI
ETIKPLPWRQSLTPTRRQETIRPIFWANRAKSYISRTENWDEYPNGRFGDARSPAYGELD
GYGISLKQTVKDALKLWGQPETVADVSSLFARFCRGDLSALPWSDQPVAGETTAIAQHLA
KVNELGFLTINSQPAVNGARSDDKLFGWGPSNGYVYQKAYLEFFVNPTLLNILLSHIERD
GNITYHVINKRGDLRTNTQSEGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAYELGQQ
WARIYESGSVPNKVVSDIMNTYLLVNVVHNDFQDPEAIFRPFYQAGAEYITKIQSQAPVT
ADH
>A0A8H7DT60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oyster mushroom|TrEMBL
MKISQKIQQSTKEGKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQSMIGVETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPQGKDE
WEAVEDGFVHGIDLVKHIRRIYGDYFDIAVAGFPQHMLLPPDELAFEMKCLKEKIEAGVN
FIFTQMFYDVEIFIEWVKAVRAAGITIPIVPGIAPIQTWNGFVRATSLAKTIIPQSFTEA
LEPYKNDDEKVRAIGTRLVADMCRRILDEDLGIRGLHFYTMNLEKATKMLLEELNLVPRI
ETIKPLPWRQSLTPTRRQETIRPIFWANRAKSYISRTENWDEYPNGRFGDARSPAYGELD
GYGISLKQTVKDALKLWGQPETVADVSSLFARFCRGDLSALPWSDQPVAGETTAIAQHLA
KVNELGFLTINSQPAVNGARSDDKLFGWGPSNGYVYQKAYLEFFVNPTLLNILLSHIERD
GNITYHVINKRGDLRTNTQSEGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAYELGQQ
WARIYESGSVPNKVVSDIMNTYLLVNVVHNDFQDPEAIFRPFYQAGAEYITKIQSQAPVT
ADH
>A0A2D0AB71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium esperanzae|TrEMBL
MALKNEGRGRNFGISFEFFPPKSEEMEGQLWDTVAKLQDWDPDFVSVTYGAGGTTKAPTL
SAVTRFLSQTPLATASHLTCVGATKEETHQMIDTFRKVGVKHFVALRGDAPGGVGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGISIPIVPGIMPIQNLTQLKRFAGACGAVIPAFLDERFAGFDD
KPEDRAKVAAEVAAEQIEDLVRRGIGDFHLYTMNRAPLVSAVLDNLGYSRRAAKSAGAAA
>H0EJ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glarea lozoyensis (strain ATCC 74030 / MF5533)|TrEMBL
MSMPNMDLEKITSKIAALPPGSSYFSLEFFPPKTAMGSSNLRARLDRMSRALRPLFVTVT
WGAGGSTADKSLELAELCQRELGLTTCLHLTCTNMSKELVDRALEDAKALGIRNILALRG
DPPRGEEYDMGKGEGFEWAIDLVKYIRKQYGDYFCIGVAAYPEGHADEGHPEGQSLEHDI
PYLVEKTKAGADFIMTQLFFDVEAYDKFETRLREHESGAFKTIPIIPGMMPIQSYQMIKR
TTKLSHAKLPTNIVDRLDPVRGDDEMVKKVGVDIVSEIVTHIKERPSPCPRGFHFYTLNL
EKAVSFILERTDLIPTSPADDETAILEVPMHHLTVNGSGKHSRRHSSVGSDPHNRVIINE
PKAPLSEFETTASEAGLHAEALNTRANTLAISEGEGSLGREATWDDYPNGRWGDARSPAY
GEIDGYGVSLHMSINQAIKLWSYPKTTDDITSLFIRHLEGTVAALPWSEEGLNEETNTIK
PQLLSLNRKGWWTVASQPAVNGVRSSDPIFGWGPKNGFVFQKAFVELFVPASDWKSLHKK
LTSPEIAPLVSFYASNANGDLVQSYDGEGESTNAVTWGAFPGKEIITPTIIEEVSFRAWA
EEAFGIWDEWGRVYAGKEGEDSRRLIEGFRGDRWLVNVIHHGFVEREAGNMRRECPTFYH
YFEEILISKRESWVVE
>A0A1G6Z5S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter pacificensis|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALSA
RSETEIAPHMSCIGDDKAQIAELLEFYKSLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
FIREYSGDHFHIEVAAYPEMHPQARSFEFDVDNLVNKYRAGANASITQFFYNADSYLYLR
DTLEKRGIDTIAQPLVAGIMPITNSSNLIRFADSCGADIPRYVRKRLADFGDDSKSIREF
GFDVVYRLCERLMSEGVPAMHFYSMNKVEPNKRLVEALGLTV
>A0A0Q4UN52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf257|TrEMBL
MTNTILTQAEAALAHDEPLFADVGGDIAVSFEFFPPKTEKMDAQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTMDAAAHLTCVEATREEIDQVAQEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPDSVDKQADIDNLK
RKIDAGATRAITQFFFSPEAYFRFRDAAAAAGITAEIVPGILPVSNVAQTRKFAAMCGAC
IPDWMDRLFEGLDDHPAARQLVAATISAEMCRRLYAGGVKGFHFYTLNRAELAYAISHLL
GVRGKKAEAVAAA
>A0A5J5LES6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula hispanica|TrEMBL
MALGTRAVSDSQGVRTLLTSARFELMPFESFDEEITHLPDNATIAITTSPQLGIEKTVEK
TEEAAEMGYDVVPHIAARYVEDQEQLEAIAERLEQAGITDIFVPGGDREEPAGEYESAHG
LLEALAETEYSFEEVGITGYPEGHDFIDDETLAESMAQKAPYATYIVTQLCYDPDAVLEW
VESIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDDEYNIRGVHIYTFNQTPDTEKWRHNRLDS
>A0A256Z065|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon ex4484_40|TrEMBL
MPCWGRPLEPELIKFGKKVSAGAEFFQTQVVFDIETVKRFFDEIKGYNVPVLIGIFPLRS
YGVAKYFDETVPGVKVPEELMKALAEAKRIPDKKRRRQRYNEINLEYFTNLLKEIKKTTP
AAGCHLMSVGYEEIIPSLVEAVK
>A0A521E220|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melghirimyces algeriensis|TrEMBL
MAKRQDLGTALTGSLLVGDGAMATYLYQLGIPVGIPVEELSLTRPQWIEKVHRRYLQAGA
KILEANTYGANRERLARYGLEGKVTRINRESVAIARRVAGDTAYVVGAVGSINAGRVPNW
SRSEYRDLYEEQVTALLYAGVDGLILETFLDLEELILALETARTLTEKPILCQITMMEVG
RTRDGYTLTDAFEQLKKHGADGVGLNCRQGPLEIQRALEKTVVPQGLILSAYPNAGRLGM
TDEGFQYASTPDYFKDRAMALREQGVHLIGGCCGTTPDHIQAMSEALEGLSPMPRINPDL
VEEKMERPRLEVRTQPTLVEKVRNETTVIVEFDSPKDLDIHDYLYGCEQLNKSGVDAITL
ADNSMATTRMSNMALASIMKQRTESEPLVHITCRDRNLIGQQSHLMGLHALGIHQILVIT
GDPTRIGDLPGASSIYDVNSFDLIRMVKQLNEGISFSGKPLKQKAQFVVGAAFNPNVSRM
EAAVGRLKKKVEAGADYIMTQPVYDVESIQNVYQATKEIPVPIFIGIMPLTSYRNALFLH
HELPGVKIPDRVIKQLEGMNASQARVLGVEMAKELLDEAMKYFKGIYLITPFHYWKMTAE
LTRYIRSRQKQKTPVAFEQK
>A0A1E3YEK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium SCN 69-37|TrEMBL
MQGFLDALDRRVLVCDGAMGTVLYARGVFLNRSFDELNLSAPDLVAEVHREYVRAGADVI
ETNTFGANRIKLTTFGLADQVAAINSKGARLARRVARDRAWVAGSIGPLGVRIEPWGRTT
VADAEAVFGEQAAALVEGGVDLFILETFGSIAELTAAIRAVRAVSPLPIVAQLTTVEDGS
APDGTPVERFPGAIEQAGADVIGLNCSVGPAAMLDTIERMTRVYAGRLAAQPNAGRPRDV
DGRNLYLSSPEYMASYARRFVAAGVRLVGGCCGTTPEHTRQIAEAVRRSAPVTRHAASAR
VTPAAEATPATPTGTPPPSSDLARSLASGTFALVVEMAAPRGLDVEAAVAQARRFCDLGA
VAVNVPDYPRSGARASALALAALLEQHGIETLLHYTCRDRTLAGMQSDLVAAHVMGIRNL
LATTGSPSRQGNFPDVTSTYELDAIGLLNMTSRLNAGRDVAGEPLDGATQFHVGATINPF
AAEPDVEWQRLERKIAAGAGFIMTPPVLDPEALEPVFARLARLGLPVLAGVAALEHARHA
EWLSSEVVGVRASEAILDRLRRAADPAAEAAAVTTEIMAWLRGRVQGLVLTWLHGSAATA
EQRIMDAGTGADGDRSALHGATHE
>A0A643F0U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella pituitosa|TrEMBL
MGFYGLSRRSDIGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLKPEFVSVTYGAGGSTR
ERTIRTVARILKETDIEPAAHLTCVDATREEVDRVAQEFAALGVNRFVALRGDPASGIGE
KYVPTQGGYQNGADLVGGLRKLSDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVSNFCARSATHIPAWLAERFD
GLDKDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTEAEL
AVA
>W1Q2Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Abiotrophia defectiva ATCC 49176|TrEMBL
MTQPPAPFHHPSLSYEVFPPNTQVGAERLTHTLNDLAELKPDFISVTCSNRQPNIEETTL
KVANHVQNTLHIPTIAHLPAMYLSKERVADSLDSLDQLGIRRVLALRGDILEGLEPVGDF
SYAEELIHFIKERKPHFDITAACYPEVHPDAPNAVADIRFLKRKVDAGVDRLITQLFFDN
DCFYHFQEKCALANIEVPILAGIMPIVNRNQALRLLTTCETTKLPRKFKAILDKYEHEPQ
ALRAAGLAYALDQIVDLITQGADGIHLYTMNQSDTAHYIADAAKALFK
>A0A315Y015|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus flavefaciens|TrEMBL
MRIKDIFKEKTVFSFEVFPPKKTSPIEVIYSTLDELQGLHPDFISVTFGAGGSGNSRYAL
DIASRIKDSGIIPMLHLPCINFTKAEIDAALTEAQQRGIENILALRGDINPDIEPVEDFR
HASDLITYIKTKGCFDIAGACYPECHPDAENMVEDIINLRKKVEAGADHLITQLFFDNDH
FYEFREKAAIAGINVPIEAGIMPVVNKNQIERMVTTCGASLPSKFVRIMTKYEHNPEALR
DAGIAYAVNQIVDLVASGVDGIHLYTMNNPYVARKISEAVSGIIGA
>A0A1Q5GWB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02366|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPQDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLEKFSQLSNATV
PEPLKERILAAKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A4V2HEM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas winnipegensis|TrEMBL
MTPISFEFYPPKTDEQRAQLNRTAERLARYAPEYVSCTFGAGGSTLSYTAETVRHLKQHH
GFDAAPHLSCVGGSREEIRELLKLYRAIGCKRIVALRGDLPSGMGHAGDLRYASELIAFI
RAEHGDAFQLEVGAYPETHPQASDALSDLKHFKAKVDAGADAAITQYFYNADAYFGFVEA
VRRLGVEIPIIPGIMPIANFAQLRRFSEQCGAEIPRWIAKRMAAYGDDAAAVKDFGADVV
AQLCQRLIDGGAPSLHFYTLNLAKPTQTVLQRLGIR
>A0A0G9H170|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella japonica DSM 16301|TrEMBL
MSSFSFEFFPPKTDEQRAQLDQAAALLKSRSPEYVSVTFGAGGSTLSYTGETVHRLHTDH
GFSVAPHLSCVGGTRAELGALLDDYRAAGYRRIVALRGDLPSGMATPGDFRYAAELVRFI
REHSGDHFHIEVAAYPEMHPQADDALADLRHFKAKVDAGADGAITQYFFNADAYFRFVDD
VRRLGVNVPIVPGIMPISNYSQLKRFSDGCGAEIPRWIAKRMLAHGDDAASIRELGADVV
AQMCRRLLEGGAPSLHFYTLNRARATLAILDRLHG
>B5FBP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliivibrio fischeri (strain MJ11)|TrEMBL
MAYSHASHLESLNQNIAELDGNINVSFEFFPPSSEKMEETLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLIAAPHLTCIDASRSELIDIANDYWANGIKDIVALRGD
IPPGGGAPEMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQASRFAKMNNVKIPGWMAQQFE
GLDDDPVTRQMVGASHAIDMTRILSREGVKDFHFYTLNRAEHTYALCHTLGVRPK
>A0A1H0W7Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentzea jiangxiensis|TrEMBL
MTSVVERLQGESPKFSVEFLPPRDAEDEKVLWKAVRELEGLDPAFVSITYGAGGSRRDRT
IRATGRIAQETTLLPVAHLTAVDHSVAELRNVIGWYAAIGVRNVLALRGDPPGDPMGEWV
AHPEGLNYADELVRLVRELGDFCVGVAAFPYGHPRSADLDTDLKFLLRKLNAGADYAVAQ
LFHAPEPFLRLRDRVAAAGCDAAILPGIMPMLSPRGLSKIVELSGADLPPEVSRRLEPYA
DDVAGFRATGIDIATEMCRRLLDEGVPALHFYTMNRAKATREVLGRLGLVTRA
>A0A836QPG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTDSDAGTLDDSRSTHSQGRLERLLRAGAFVVTAETTPPVSADPAALLEVTEDLRDWADA
VNVTDSAGAKSHMASLVAASLLIRAGIEPILQFTVRDRNRIALQNDLLGAGALGISNILC
LTGDNISAGDQPDAKMVMDLDSRGLVSLARDMRDSRQLPTGRPIEKAPGLFIGATDSPQE
PDNEWSATALQSKVDAGAEFFQTQFCFDIDLVRRYMERLENEGVLERAYFLIGIGPIASA
KSARWMNQNLFGVDIPESLIGRLEQATNQQAEGRRVCLELIQQLREVTGVSGVHLMGPQA
ERSAAQVIADSGILNERPEVA
>A0A7T7VNX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceicoccus sp. YJ47|TrEMBL
MTDPVSASPADCITADGVPLFASLPGDIGVSFEFFPPKSEKMEAQLWDAVEKLAPLAPEF
VSVTYGAGGSTRERTHATVERIIREARIPAAAHLTCVEASKDDIRRVAEQYWEAGVRHIV
ALRGDPTTPGGRFEPHPDGYAGAADLVAGLKAIAPFEISVAAYPETHPEAQSAQSDLDNL
KRKLDAGADRAITQFFFRPECFLDFRDRLAADGVDAPLVPGILPVSNVAQTRKFAAQCGA
QIPAWMDGLFEGLDERPGARKLVAATLAAEFCRRLYAGGVRDFHFYTLNRADLSYAICHL
LGRRPVAAEQTEQAA
>A0A836QQR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSGAGVKSLRKLGHKDRAALAVSFEFFPPKTEKMLERLWRSVDRLAPLRP
>A0A8C0QFA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Canis lupus familiaris|TrEMBL
MVKEPRGDGDGGPTPRSEGSSSGSESSKDSSRCSTPGLDPERHERLREKMRRRMESGDRW
FSLEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLV
RHIRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHF
VKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGI
EQAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLAREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYL
SGEPNQHGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVG
WGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKVGRGFRGRLTWD
>A0A7Z9K5J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTDSDAGTLDDSRSTHSQGRLERLLQAGAFVVTAETTPPVSTDPAALLEVTEDLRDWADA
VNVTDSAGAKSHMASLAAASLLMRAGIEPVLQFTVRDRNRIALQNDLLGAGALGISNILC
LTGDNILAGDQPDAKMVMDLDSRGLVSLARDMRDSRQLPTGQPIGKAPNLFIGATDAPQE
PDNEWSATALQSKVDAGAEFFQTQFCFDIDLVRRYMERLENEGVLERAYFLIGIGPIASA
KSARWMNQNLFGVDIPESIIGRLEQATNQQAEGRRVCLELIQQLREVAGVSGVHLMGPQA
ERSAAQVIADSGILNERPEVA
>A0A433YDA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus anaericanus|TrEMBL
MKLDLRKAWDNNVLVGDGAMGTYLYQLGFPVGISFEEFNLVRPEVIGDVHRHYIEAGAQL
IETNTFSANFNKLSKFGLESKVEEINRAAVRIARKAAGSNAYVAGAVGSIRGGKRADVSV
QELSRYFEEQISALLTEGVDALLFETFYDLEEMRIALQKARKLTDIPAICQFAVDQVGRT
LDGYSITEAFGTLRQEGADVFGFNCHSGPKGIMNVMNMLDGPLNIPLSVFPNAGLADYVD
GEYIYGATPKYFGDCALSFADLGARLIGGCCGTTPEHIAAISQALQKYVPRPLSEGRELP
LTQASIVIAEREQISNNEASIDQSTDVPSIVEMVKDRHTVIVELDPPRDLDIAKFMKGAA
ALKEAGIDALTLADNSLAVTRMSNMALGHLVQSQLGIRPLIHIACRDRNLIGTQSHMMGF
DALGIDHVLAVTGDPARFGDLPGASSVYDLTSFEIIRMIKQLNEGVGFSGKPLKQKAKFV
VGAAFNPNVKYLHKAVERLEKKIASGADYIMTQPVYDPELIVAVKEATAHLDIPIFIGIM
PLASGKNAEYLHNEVPGIQLPEVIRNRIAGLQGAEGRQMGVEIAKELLDTAMEHFNGIYL
MTPFMFYEMNVALMNYITEKSKRSVSHLSHS
>A0A231PMV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. XY006|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERMLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSTDWDTDVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDRVSAAGCDTPIIPEVMPIASVRSLERIGSLTNAAF
PAALKERILTAQDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPSQA
>A0A417C195|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM42-4|TrEMBL
MKIRDILAKNEPTLSFEVFPPKTEDKYESVEAAASEIAKLNPAFMSVTYGAGGGTSQYTV
DIAASLKAKGVTPLAHLTCVSSTREKVHSVLDQLKAEGIENVLALRGDIPKDGKVEKDYR
YASELIAEIKASGDFCIGAACYPEGHVESVNKTEDIQHLKEKVEAGCDFVTTQMFFDNNI
LYNYLYRVREKGITVPVIAGIMPVTNVAQIKRICSMSGTYLPARFKAIVDRFGDNPAAMK
QAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNSLSEIIR
>A0A1H8R6K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rubidus|TrEMBL
MRPTFSFEFFPPKTDAGTARLWETIRRIECLRPDFVSVTYGAGGSSRVRTLALTEAIAAH
TTLRPVAHLTAVGHSVAELRHIAGQLAAGGIRDVLALRGDPPGDPAGPWHPHPQGLTYAY
QLVELLRDLGDFRIGVAAFPEKHPRSPSFEQDVAHFVAKCRAGADYAITQMFFRVEDYLR
LRDAVTAAGCHTPIIPEIMPATDYRQIARFAQLSSAVFPPGLAAQLHAAAGDPAAGRAVG
VRHATAMATRLLDEGVPGLHYITLNTAPTAVDIHRNVLSARPALAALPAA
>A0A3D6EC28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium|TrEMBL
MNVAEIIKNSSRTAFSFEVLPPLKGNSIDKVFDTIDALREFDPKYINITSHRSEFIYKAA
DNGLYQRVSEKSRPGSVAVAAAIQYKYRIPAVPHLICSGFTKSETEYALIDLNFLGITDL
LILRGDKAKHEARFSPSPEGHAHAIDLQQQVNRFNEGYFLDGSHMTLSSPFSYGVAGYPE
KHDEAPNLETDLRHLKAKVDAGASYIVTQMFFDNAKYFAFVERCRAEGITVPIVPGLKPI
TSANQLTVLPKVFHVDLPEPLARELAACRDDAAAREVGVEWCTTQARELKDRGVPSIHFY
SLMATESVRRVARAVY
>A0A537SIF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MMSPPPPHPDSRLEALLRARQFAITAEITPPVACEAEDLLRKATPLAGLADAVNVTDGAG
ARAHLSAPIAACLIARAGIEPILQFTCRDRNRLALQADLMGAAACGVRNILCLTGDDPKA
GDQPQTKPVFDVDSVALTAIARDLRDKGELPSGRKVTGRAPFFIGAADVPIDPPPDWRPD
KLAAKAAAGAAFVQTQFCMDAGVVRRYAARLAEHAPTRDLFLLIGIAPLRSAKSARWMQQ
RLYGTIIPQRLVERLERAGDPAPEGERIAVELIEELAAIPGVAGVHLMAPANEDALPRVI
ADARKRLPR
>A0A537WIQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSDKSRAAAAPQRGLLSADPVGDFDGAAPRVSFEFFPPKTPEMEARLWEVIKRLESLAPR
FVSVTYGAGGSTRERTHATVRRIRNETALEPAAHLTCVAASCEEIDRVARDYWEAGIRHI
VALRGDPPGGLGSDYAPHPGGYAYAADLVAGLKRVADFEISVAAYPETHPAARSSDHDLD
NLKAKLDAGASRAITQFFFDVDLYLRFRDRAHDAGIRVPIVPGILPVTNFAQLKRMSAGC
GASIPGWMAAHFDGLDDDPDTRRLVAASLAAEQCRRLHANGVHEFHFYTLNRADLIVAIC
HLLGVRAPRAAAATA
>A0A537RNJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
KQTKAFAARCGASVPDWLAERFDGLEDDAATRKLIAAAVAAEQVLDLVDRGVTDFHFYTM
NRADLVYAVCHLLGLRPNQETDALPLPIMEKERA
>A0A0C2JHU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomonospora alba|TrEMBL
MVGSSTRNGSAPVAASRPRDIRELLKTGEPTFSFEFFPPKTDEGLTKLWRVIRDIEALAP
SFVSVTYGAGGGTRDLTVEITEQLQTDTTLLPVAHFCAVNHSVSELRHLVGRFASVGVNN
ILALRGDPPGDPLGEWVKHPEGLEYADELVRLIKELGDFSVGVAAFPYKHPRSPDIESDT
KYLVQKCRAGADYAITQMFFDPEDYLRLRDRVVAAGCETPIIPEIMPVVKYSTIEMSEQL
SGAPFPRHLAEEFEKVKDDPESVRKMGIEQAQRMCERLLDEGAPGIHFITFNQSTATREI
YQQVAADRLPAMAGARP
>A0A1I2AEC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter brevis|TrEMBL
MRNLSMTAPNVSFEVFPPRTVDAAFKLWDTAQALAPLAPRFFSVTYGAGGSTRDITHDAA
HVLRRTSGLPVAAHLTCVGASRTETLEVAESFAEIGVTDIVALRGDPADGAATFTPHPDG
FADSCELIEALAKTGKFNIRVGAYPDPHPESTDVQANVDWLKRKFEAGADEAITQFFFEP
ETFLRFRDACDKAGITKPITPGILPVVNWTSARKFANRCGAFIPDWVDQAFDAALRDGDD
RHDLLATAICTELCSDLMNEGVENLHFYTLNRSDLTRNVCRALGVLPKVALSDVA
>A0A3E5BAX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides oleiciplenus|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFAPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAGAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIHWLKQKMEAGAEYAVTQLFYDNRKYFDFVERAQKAGVTIPIIPGIKP
FKKMSQISMIPKTFKVDLPEELAREAMKCKTDEEAKQVGIEWCVQQCKELVGHGVPSIHF
YSIGAVDSIKEVAKQVY
>A0A1Y3CQP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4470|TrEMBL
MTKRIPVSFEFFPTKTDVGAEKLRVVHQELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELSYASDLVA
FIRQHSGDHFHIEVAAYPEMHPQAESFDKDIQNFITKARAGANAALTQFFFNPDAYFYFV
DRLQKEGIDLPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNQTEPNRQLVLDLGLA
>A0A3M1JTF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSGDIAQAGDFRPNLFAFARGDVQVSFEFFPPKTEKMERTLWETVTGLAPLRPRFVSVTY
GAGGSTRERTHNTVLRIQREAKLPVAAHLTCVGSPKAEVDAIARRYWDEGVRHIVALRGD
PPEGEAGYRPHPEGYRNAADLVAGLKSIADFEISVAAYPERHVDSPDWTAELDNLKAKVD
AGATRAITQYFFDPALFLRLRDRVAAAGIAVPLVPGIMPVTNFQGIVNFSKRCGATVPDW
LAELFEGLDDHPATRQLVAAAVSAELCRRLYDEGVTEFHFYTLNRAALTYAICHTLGVRP
RGEGTKP
>A0A2W4UVN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MAASSTNLAEARALLLSPLGPVARAGSNHDAVRVSFEFFPPKTDEAEANLWTAIRRLEPL
NPAFVSVTYGAGGSTRERTHRTVQRIIAETSLRPAAHLTCVEASRDEVDEVIAGYKTIGV
DHIVALRGDPPGGGGIGGVYQPRADGYANATELTAAISRVGGFDVTVGAYPEKHPESPSI
DHDIDVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLTR
MCGACGTSIPDWLKAHFDGLDDDPETRRLLAASVAAETCARLHEEGFSDFHFYTLNRADL
VYAICRVLGVREQKAAA
>A0A537VFF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MHAEPRASRFVQRLGEGEPRRIRVSFEFFPPKTEEMEKTLWESITRLAPLKPNFVSVTYG
AGGSTRERTHSTVKRILGETALTPAAHLTCVAATCEEIDAVIRSYCTAGVRHIVALRGDP
VGGVGERYAPHPAGYRNAADLVAGIKRLSDVEVSVSAYPEKHPDSPTVEADLDMLAAKVD
AGAARAITQFFFENDLYFRYLDRVRARGIDVPVVPGILPVQNFKQTKAFAARCGASVPDW
LAERFEGLEEDAATRKLIAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAVCHLLGLRP
SHEASGGHGALPLPAGERAGVRGVG
>A0A537KZX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MPPVKSQGQLETAIASGRFVITAEITPPVSCSPDELLAKATPLKGLADAVNVTDGAGARA
HLGAMAAATILHQNGIEPVLQLTCRDRNRLALQSDLLGAAALGIHNLLVLRGDDPSAGDQ
PDAKPVFDLDSGALIETAVRIRDRGTLPSGRKVTGKADFFVGAADMPIDPPPD
>A0A552M5L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis wesenbergii Mw_MB_S_20031200_S109D|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFPGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFERLDKFMQQVAAIADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDMAGIPPIHN
>A0A357YW38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacter sp|TrEMBL
MKTESRLEKVLASGQLAVTSEVGPPRGCNIDIVKEKANMIKDYVDSINITDNQTAMVRMS
SIAGGIVIKQMGLDPIIQMVSRDRNRLAMQSDILGAYALGCNTMLCLSGDHPQFGDHPMA
KPVYDIDSINMIKMVKDMRDEAKFQGGADITDPPKMFIGAAANPFADPFELRVMRLAKKV
AAGVDFIQTQCIFNTAKFETWMKQVVDRGLHEKVAILAGITPMKSLGMAKYMKSKVPGMD
IPDEVIDRLAGVDKDKQAQEGIKMAIEQMQRLKECKGVKGFHIMAIEWEEKVPELVKGAG
LYPRPQV
>A5GQH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. (strain RCC307)|TrEMBL
MSNLLASSLEKALASGQPVITAEITPPVGADPSHALEMAEGLRGQVQAFNVTDGSRAVMG
MSSLALCRLLLERGLEPILQLGCRDRNRIALQADLLGAHALGIRNVLCLTGDPVKAGNQP
EARAVFDLESVRLLRQVQQLNGGVGPAGKPLADGAPALFPGAAADPQSASWSGLKSRMRR
KAEAGARFVQTQMVMDASALRRFCTEIAAPLNVPVLAGVFLLKSAKNAAFINRVVPGAQI
PLPLIDRLAAAENPRLEGIRIAAEQVQSYSAIAAGVHLMAVKAEESLPQVLELAGLPKVV
AQV
>X5YJ07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNJC399B00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTIKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A4U0HCN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. CAU 1506|TrEMBL
MASRLLAATDEDRQTLATLLDNIGYEIMPFKSAKDKVLAEVPTSVPLTITATGGKGLEPT
LDAAVFLRGRGYSVAPHVPARLVRDVEELDALVSRLEAAEIDRIFIIAGDAEEAAGEFRD
ARSLLAALTDRGHHFTDVGIGGYPEGHASFPDEAIRQALRDKAPYATRILTQICFDPQTF
LEWGAQIKREGVALPIYAGMPGPVSRQKLLRVSAGLGLGQSANFLKKQQNMFWRFFSPSG
YKPTQLIKGLVQGLPASNAAIKGFHIFTFNDLAQTEVWRRELLEQAHG
>A0A3M0WN67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MRISLEFFPPKGVAESFRLALAAERLATLAPEFVSVTYGAGGSTRALTLETAEALRQRWG
FEVVPHLTCVGATRGEVLAVAERYVEAGFGTVMALRGDPPGGAGPFRPHPEGFANSVELV
RALARMGDLRIGVAAYPERHPEAADADADFEWLRRKFDAGASFAITQFFFDVEAYLRLRD
RAAAAGIDAPIIPGLLPVSNWTTVRRFAERCGASLPRWLVEAFERARRDGRERLLAVAVA
TEIADRLRSEGVEQLHLFTLNRATLSLQLCAALGIGPSGAPAAGPLRLDAVA
>A0A3M1C5M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
SVELIAALADTGRFTIRVGAYPDRHPEAASDDADIAWLKRKVEAGAASAITQFFFEAETF
FRFRDRAEKAGIDVPIIPGILPIENWAGVKRFAARCGARVPGWLDEAFEKAIRDGREELL
SVAVATELCADLVEGGVEDLHFYTLNKPGLSRDIAHALGVTPRLALRNVA
>A0A156LKV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter hormaechei|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVL
>B3EPY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium phaeobacteroides (strain BS1)|TrEMBL
MLVKEILNSATGPVFSFEFFPPKKTEDWGKLFHTISELIPFNPSYVSVTYGAGGSTRSRT
HDLVTKIQRETGLTVVSHLTCICSGKKDVAEILEDYRTQGITNVLALRGDLPPGSTSYEE
ATKDFPHAVDLVKFIVENFPEIGVGVAGFPEGHPQTPNRLKEIEYLKAKVDQGADYIVTQ
MFFDNRDFFDFVGRCSLAGINVPIIPGIMPVTTKKGLIKMSELALGARIPAALLKKVLEA
PNDEEVAKTGIEWATEQTRELIENHIRGIHFYTLNNAEATRKIFTNIADRARA
>A0A7W7YE51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecobacter vanneervenii|TrEMBL
MHIHDILSATRGTTAFSFEFFPPRTPAAVKTLQTTLDHLAPLRPAFASVTYGAGGSTREL
TQSLVTELRQSDVFDPIPHLTCVGHSESDIMALLTRYAAAGVSNILALRGDPPSGGTGSG
DFAHAADLVCFIRQFNERGLHPDPRGFGIGVACFPEGHPATPNRMTEMDHLKAKVDAGAD
WLCTQAFFDNHDFHDFRARCALAGIHTPILAGILPLTTASGMQRMAALAGGMRYPARLIR
ALNRAKDDPEAFRRIALHHAAEQCTDLLDHQADGIHLYTLNQAQPVLEIHARLGLR
>A0A2T4PX24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mammaliicoccus vitulinus|TrEMBL
MNLKKALKNRILVADGAIGTILYSEGLDTCPESYNLTHPKKVEQIHRSYIEAGADVIQTN
TYGANFEKLQDFNLEHRVKEIHREAVQIAKKASNKDTFILGTVGGFRNIKKSHLSIEAIQ
YHTEIQIETLVNEGVDGILFETYYDLEELLTVLKDAKAKYDIPIIAQLTASNTNYLRNGT
PIPNALEALLNEGADIVGLNCHHGPYHMIKTYKHIEIPDNAYLSCYPNASLLDLEENDLK
YNNNSEYFSDAAKELVNQGVRLIGGCCGTTPEHIKKIKNIVKDLTPIKHKNVIPIETKQY
KKQNKNEPSIKELVQQRPTVIVELDTPKHLDTNRFFEGIQALEDAGVEAVTLADNSLASV
RISNIAAASIIKEKYKIRPLVHLACRDRNLIGLQSHLMGLSLLGINDILTITGDPSKVGN
FPGATSVFDVNSSGLAEIITQFNQGINADGDTLRSNTNFSVAGAFNPNVRRLEPAVKRLE
KKVESGMEYFITQPIYEPERVKEIYEATKHIDAPIFIGIMPITSYNNALFLHNEVPGIKL
SETVLNAFEKVKDDRDATRKLSISLSKQLIDAVHQYFNGLYLVTPFLKYDLTVELANYSK
LKTGTQTKEAIL
>A0A534HXR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MHSGSRLERVLASGAFAVTAEIAPPPSADPGAIRTQAAAYRGLVDACNVTDGTRALVQMS
GLAAAAILIQEGVEPVLQLASRDRNRIALQADLLGAAALGVRNVLCLFGDLPAGGNEPDA
KGVFDLKTEEMIETFRILRDKGVLRGGDPVESAPRIFIGATADPFQDSREESFARLRSKV
LAGADFIQTQAVFDVDAFEEWMRLVRKEWLHEKVYVLAGVIPLRSSKMARFLGDKLGMAV
PRHILDRMEKAPNPQAEGVSIAVRTIKALRKIEGVRGVHLMPVGWEDVLPELVKEAGLVP
RPETPG
>A0A2E4YU76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MAEGALFDSSDGGTPISIEILPPNRGLGLDXIHKFFSGLNGWKPAFVSVTYHQSHKIDVV
DEDGRNNKIWNRKKPGTLGVCAMLKFKYGLKVIPHLICGGFSRFESEDFLVDLDYLGLEH
ILALRGDPKKGDEIFTPHPEGNAYASELVEQITSLNNGKYLEGVQEARPTNFKIGVAGYP
EMHREAASRKIDLENLKRKVDAGASFIITQMFFDNNVFFQFEKDCRDLGIDVPIIPGIKV
XTSKKQIDILPKMFHTMIPDSLGERILRCHDREQVIELGVEHAIRQSNELREYGAPCLHF
FTMNDLGTFSKVLNALRS
>A0A840IUK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis jiangsuensis|TrEMBL
MTSVIERLQGDAPAFSVEFFPPRDEADEAVLWRAIRELEPLDPGYMSITYGAGGSSRDGT
IRSIARVATETTLCPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPEGLTYAEELVELVRSLGDFCVGVSAFPYGHPRSADLETDTKYLVRKFRAGADFAIAQ
LFFEAEDFLRLRDRVAAAGCDALVLPGIMPLTTPRTLRTTIKLSGAPASQRLLDRLEPFE
DDPKAFRAAGLDAVTELCEKLIAEGVPDLHFYTFNRSKATREVVTRLGLAPPRA
>A0A7G9TNU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium sp. Z12|TrEMBL
MAPPPPVAGALGPEPQYEVIPLRGIAREVAAQLPPGARVTVTASPAQGLPATIETACELA
EQGFRAIPHLAARMLHGRSEVEELLERLAEAGVAEIFVIAGDASLPAGDFPGALELLETL
SSAGSAMTVGVGAHPEGHPHLADAEATRLLQVKAEHATYAVTQMCFAAAPLLEWTRQLRD
ADITLPVRPGIAAAVGTARLLRIGARIGVGRSLRLLGGEDPGMRRLLSPGRWEPGPLLDE
LGTAAAEEPGLALLGPHVYTFNDLRAAREATAHR
>A0A2V5LAH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter livingstonensis|TrEMBL
MSPPGLPQAPSGAGAPIALSYELFPPRNEKAAASLWDTIRELEGTNPDYVSVTYGANGSN
RGTAVELLNRLLRETTLRPLAHLTCVGNTADELSGIISELLDHGVRGILALRGDLPRDPG
DGPRQGSLRHAQDLIELIRRVEQGRSALLCAGKVAIGVAAYPAKHPESPSVEHDVEVLLA
KQRSGADFAITQVFFHADQYRELVVRARRAGVRIPIIPGVMPLTSLRRVRRLGVLTGVDP
APKLLDALGRAGDAAESRRVGVSATVDLARAALDAGAPGIHLYTFNEHAAALDVLDKLQL
LRPARRAPAPELVQA
>A0A7I0AK15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus epidermidis|TrEMBL
MSHLLNQLKSNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKSFGLEHKVKEIHQAAVQIAKRAANEDTIILGTVGGFRGVRQEDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELTRIVTATRQKYDIPIIAQLTASNTNYLVDG
TEINEALKYVVECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDIAQELINEGVRLIGGCCGTTPEHIRYIKSAVKHLKPVKDKKVIPINKAS
SQKETRVLKQNLTSKVKNGPTVIVELDTPKHLDTDTFFDNVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQRYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGINTDGDALKKHTNFNIAGAFDPNVRKLDGAIKR
LEKKVASGMSYFITQPVYSKEKIIQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSDDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A2I0UV08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus fusiformis|TrEMBL
MRLLERLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQKPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLDEI
LATIEEQASVLLAGNPDGLLLETYYDFEELTATLKMLRTKTKLPIIAQVSMHEPGVLQNG
MSLNNALHELEKLGADIVGVNCRLGPHHTIQAFEGVELPDKAFMSAYPNASLLDLEDGRV
VYESEAEYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVHEKYAKPEKIQI
VREAEPTKYEPLHEKVKRERSVIVELDTPRHLEIDGFLEGAKQLYDAGADVVMMADNSLA
SPRISNIAMGALLKSTNGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDVLAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNQGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEYGADYFISQPVYTKEKIVEIYEATKHLQAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSEDALARMKACGEDKERATFEGIAIAKELVEVAAQYFNGIYLITPFLRYDVTLELMKY
IEQLDEQKKGVSIHG
>A0A7C4TGP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MAAGNITDISFIKSFELVPKKSYGYPEATDALDMMEGISNVITAPENPMGMPGIDPLMAL
YTATHGRNIIPVPHITPRDKNKLHIHSQVLTGMKFGINHFFAIGGDPIHKTMESREVREL
DVIGLIRAIKDSKGYSRDFSSSSDVIVGSSFNPFRGAEEDIVNAKIGSGSGFFITQAFYD
SSLLKRDWIRKRNFKLIAGFMPIQRESQIEFMKKLGAKIPEEIEKRILGAQDMVQESSKI
IKEMADDLEGFIDGIHIMPLGKNKIAKDILESF
>M2SJN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cochliobolus sativus (strain ND90Pr / ATCC 201652)|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDEALEQAQVLGIRNILALRGDAPRSEE
YRDEDTPPEQDSNKDFTWAVDLVTYIRKQYGDYFCIGVAAYPEGHSDQSHPEHQDPMADL
PYLVEKTKAGADFIMTQLFYDVEAYDKYEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHAKLPTDILARLDAVKSDDELVKQVGVQIMDEIVERIKARPDTCRRGFHFYTLNL
EKAVSHILEDTKLIPSTLIDDNEVIVETTPAINLEPPPNGIMPHRRRSSAVNSGPRNRVI
VSHVSAARSSNPSYEATEEEAGIPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPTEKNDISTLFRRHIEGDLEAIPWSEQGLSP
ETLTISKQLLALNAKGWWTVASQPAVNGIKSTDPVFGWGPKNGYVFQKPFVEFFIPASEF
AALQPKLDAHDQITYFAGNAAGDFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIWREWQRIYPPRSATSTLLGELRRDYWLVNVIWGDFVNGEGLWEFLLE
>A0A2W7QU09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus ratkowskyi|TrEMBL
MKITEHLGSATKTLFSFEILPPLKGQSLKELLEGIAPLMDFNPPFVDVTYHREEFIYKKH
PNGLLQKISTKKRPGTVGICAAIMNRFHIDAVPHILCGGFTKEETENALIDLNFIGVENV
LALRGDAPKTEGKFIPEIDGHGFASELVEQIKMMNEGRYLHEETEIGFQTDFCVGVAGYP
EKHFEAPSLRFDLKYLKEKVEKGAEYIVTQMFFDNEKFFKFVADVRAAGITVPIIPGIKP
ITTLGQITMLPRTFFLDLPDLLMDELEKCKTNAEVKEVGIEWSIQQSKELVKKGVPSLHF
YTMSKADTTYKIAKEIF
>A0A1Z4UTL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerospermopsis kisseleviana NIES-73|TrEMBL
MQDSHKTSTLNNFRKAVQAGEFLVTAEVAPPKGGNITHTIEMAATLKGRVHAVNITDGSR
AVLGMSPLAASAILLQHGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPDAKAVFDLESIRLLQLIRNMNQGVDFNHKTLNDGALDLFAGAAVDPQSKSWSGLQS
RFEKKIEAGAQFFQSQLITDFEKLEKFMDQIASRYNKPILAGIFLLKSAKNAQFINRMVP
GVNIPDHIIERLEKAKHPLQEGMKIAAEQVQMARGLCQGVHIMAVKKEEAIAPILDLAGV
EKVS
>A0A165ZJ63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sistotremastrum suecicum HHB10207 ss-3|TrEMBL
MKITEKIEQANKEGRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSELVKTCQSLIGIETCMHLTCTNMPKEKVDNALRDAKAHGCRNILALRGDPPAGKEE
WESVEGGFEHGIDLVKHIRKNYGDYFDIAVAGFPQTQTLPPAERDLEMKYLKEKIDAGVN
FIFTQMFYDVDMFIDWVKAVRAAGITVPIVPGINPIQTWNGFMRATSLAKTIIPPKFLQA
LEPHKNNDEKVREIGTKMVADICRRIIAEDVGIRGLHFYTMNLEKGTKMLLEELEFVARV
QTIKPLPWRQCLTPTRRTETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWLKQSKEEAHALWGHPTSYAQIARLFSKFCTKEISALPWSDEPPSAEMSVISSQLG
RMNELGFLTINSQPAVNGVRSDHPVHGWGPSKGYVYQKAYLEFFASPALLSTLLPYISRD
SNITYYAINKHGDLRTNSHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAFELGMQ
WANLYESGSASRSLITDMMENYFLVNVVHNDFQDTEAIFRPFWAVAAEAGLEQPEIQRLS
NGVRQLEVASVA
>A0A5R8MHF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas urmiana|TrEMBL
MSTQEHPLGISFEFFPPNTDAGREKLVGVRDALARRAPRFFSVTYGAGGSTQARTLNTVH
MVRESGFTTAPHLSCIGSDKGALRELLARYREDGIDSLVALRGDLPSGMGGSGVGQLRYA
NELVEFIREETGDHFEIAVAAYPESHPQAPNLERDLENFARKMKAGANLAITQYFFSAEA
YFHFVERARALGVEAPIVPGIMPITNYAKLARFSDACGAEIPRWIRKQLEAYGDDSEAIA
AFGEEVISRLCQRLLDGGAPGLHFYTLNQSAPCLRILDNITG
>A0A3A9G935|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. 1XD42-69|TrEMBL
MKLTSVLGQKRITLSFEVFPPKADLDFESVRQAAFQVAKLGPDYMSVTYGAGGSTRDNTL
ALAEDIQKEYGVTAIAHLTCVGATKDSIQEALRDMRHSGIENILALRGDRPQWMEQEPFT
DYHYASDLVAAIKEFGGFCIGGACYPEGHPDAANKKEDILNLKKKVDAGCEFLTTQMFFD
NNIYYNFLYRVRSAGIEVPVIPGIMPISRASQVKNAIRLSGCNMPERFKNIVDRFGTNKD
AMMQAGIIYASEQIIDLIANGVNNIHIYSMNHANVVRGIMENLSEIVMV
>A0A415RYW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus gnavus|TrEMBL
MKISDIYNKKKSLSFEIFPPKKESELKNIDETLKVLCELNPDYISVTFGAGGTSNCNRTI
ELAKKIKYDYHIEPVVHLTCLHYDKAEIDKFAKILIEEGIQNILALRGDKNPTIQEKEVF
KHASDLITYLKPKHDFCFLGACYPECHPESENKINEMKYLKKKVIAGAEILLSQLFFDNE
QFFSFVEECRIADINVPIIPGIMPVINTAQIKRMVTMCGATFPDRFQKIILKYENNKKAL
FDAGMSYALSQVIDLLANDIDGIHLYTMNNPLVARKICEGIRNII
>A0A6P8IU82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinia tenebrosa|TrEMBL
MDEKFFSLEFFPPRTPNGAVNLLGKFDRAARGCPMFCDITWHPAGDPSGDKETSSMTVAS
AALNYCGLETMLHMTCANTTKDDVTKHLQKAKGLGIRNILALRGDPPDGDEWKALDDGLA
YGTDMVRHIRKEFGDNFTICVAGYPAGHPDCNNYQEDIQHLKEKVDAGADFIITQLFFEN
KTFFKFVKDCREVGITVPIIPGILPIQGYASLRHLVKLSRLEIPQSIIDALQPIKDDDEA
IRKLGIQMALDMCRELLDSGIVPGLHFYTLNREIATREILCALGLWCSDPAASRPLPWRA
SANQKRFTEDVRPIFWASRPKSYLYRTSEWDEFPNGRWGNSSAPSFRDLSDHHFFYLRSR
AKIDERLKMWGTKLERVEDVYEAFSCYISGKENREGVKVKSLPWNDDELASETDIIKAKL
EYLNSEGILTINSQPAVNAKPSTDRLVGWGGEGGYVYQKAYLEFFTSPETVSILLEVLKD
YPLVNYHVVNAEGTVDITNCHQDTPVAVTWGVFPGKEIMQPTVVDPISFKIWKDEAFSLW
EQQWGRLYPEESRSRKVINEIINTFYLVNLVDNDFVKGTCLWHVLDKVVSIAKSKEDTKE
SHTSQPMQL
>A0A7Y0KSV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus sp. P1361|TrEMBL
MSSALQRSIEAGAVTITAEVMPPRGADPVHSLTMAQGLKGFVHAINVTDGSRAVMRMSSL
ALCRLLLDEGLEPILQLACRDRNRIALQSDLLGAHALGIRNVLCLTGDPVRVGDQPEARP
VHDYESVKLLHQVSAFNRAEDPVSGLLPDGATALFAGAAADPNCQSLSGLRRRLERKKEA
GARFLQTQMVMKPAVLEHFCNEVANPLGLPVLAGVFLLKSARNASFINRVVPGACIPESL
VARLEQASDPMAEGIAIAAEQVRSYLSLAQGVHLMAVKAEERIPEILDQAGISLVPV
>A0A1L3NB81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sporogenes|TrEMBL
MHIKELFNEKNLVFSFEIFPPKATSSIKTIHETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTSEDIDLIISELKENNIENILALRGDIPKDKNIIGE
YNYAFELIRKIKENNNFGVAGACYPEGHIECEGLEQDIRELKRKVDAGAEHLISQLFFDN
NTFYEFLNKTQQKNINVPIQAGIMPVVNKKQIEKIVKISGATLPKKFMKILDKYEYDKEA
MRDAGIAYAVEQIVDLVSNGVNGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A8H1MN18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFLSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7C3Z156|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans|TrEMBL
FIQTQCIYDMERFKKFMEMANDMGLTQRAFIMAGITPLKSVGMANYMKKFVPGLLVPDEY
ITRLKGVPKDKQAAEGIKIAVEQIQQCLEIKGIAGIHLMAIEWEEKVPEIIGAAGLYPRP
KVD
>A0A7A6WSR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYALNRAEMSYAICHTLGVRPGL
>A0A7Y9KPR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides cavernae|TrEMBL
MRNKQTSATLARLLENARYEVLPTASTEDKVLAHVPRDVTITVTASPTKGLDATLDLAER
LAGHGYDVVPHLAARMVTGRAELEEITQRLRGKGVTSVFVPGGDAEAAGDYPDALALLED
LKELGSPFAHVGITGYPESHPTIHDDLTVQSMWDKRRYATHIVSNLTFDPAVVRDWVRRL
RARGVQMPLLLGMPGPVERTKLLGMATKIGVGESTKFLAKNKGLFARLAAPGGFTGESFL
EKCAPALGEPGALVEGLHVFTFNQIGETEAWRTDMLARLRGI
>M2YPU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dothistroma septosporum (strain NZE10 / CBS 128990)|TrEMBL
MDRLTDKIAALPPDASYFSLEFFPPKTQQGFSNLNARLSRMAHSLRPLFVNVTWGAGGST
SVKSLALAELTQRELGLTTCLHLTCTNMSRKLIDEALEQARVLGVRNILALRGDPPRSDE
YRDDSVPHAEEDDSNKDFTWAVDLVRYIRKQYGDYFCVGIAGYPEGHSDQSHPEHQSVEH
DLPYLVEKIKAGADFIMTQLFYDVDAFEQYEKTLREHESGVFKTIPIIPGLMPIQSYQIL
RRTTKLSHAALPQDVLKRLEVVKGDDEAVKRVGVDILCEIVESMKGKHGKGPRGFHFYTL
NLEKVVAQILERSQLIPPTIPDKELSGEDSAVAEVDSDDFVLVDAARKKQNRRKSSMANS
QPRNRVIISHTRASSTSSNRTSQAYEAPEQDAGVPKETINSRANTLAISEGEGALGREAT
WDDFPNGRWGDARSPAFGEIDGYGVSLHVSVPDAKRLWGEPKSIEDISRSFRRHLESEID
SMPWSEEALQPETLTIKDRLLALINKGWWTVASQPAVNGIRSTDPIFGWGPKNGFVFQKP
FVEFFIPNTEWQTLKEKLDQLPQVTYFAGNAKSDFVSSNEESVNPVTWGTFTGKEIITPT
IVEAVSFKAWSEEAFGIWREWQRVHQPGSETSRLLERIRKDYWLVNVIHHGFLEPGALWD
DLL
>A0A5A9NYX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Triplophysa tibetana|TrEMBL
MVNQRSDATWQSCKSDSSGTSNSGESSKESSRCSTPVLDADRTDRLRDKMRRRIESGDRW
FSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKDKITGHLDKAKRLGLKNIMALRGDPVGADWVEEDGGFSYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEVDLTHLKEKVDAGAHFIVTQLFFRAETFLKF
VKDCRSIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEMTQVMEPIKDNDAAIRSYGI
HQAVEMCKILLASGEVPGLHFYTLNREVATVEVLRQLGLWAEDPRRPLPWAISAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSASPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELTSEESVYEVFTNYLSGQANRNGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGV
LTINSQPNINGKASSDPIVGWGPAGGYVFQKAYMEFFTSSENVAALLQVLKKYEPRVNYH
IVNVQGRNITNAPDMQPSAVTWGIFPGREIIQPTVVDPVSFMSWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFQLLDGPAAPHDGPL
>A0A1I2Q3W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter dubius|TrEMBL
MTTPAVSFEVFPPRTVGAAFKLWDAAQALAPLAPRFFSVTYGAGGTTRDLTHDSAHVLHR
TSGLPVAGHLTCVGATRAETMEVADKFAEAGIKDIVALRGDPQAGTDKFTPHPEGFADSC
ELIEALAKTGKFTIRVGAYPDPHPEAADQQANIDWLKRKFDAGADEALTQFFFEAETFLR
FRDACVKAGIDKPITPGILPVVNWTSARKFAVKCGTPIPEWVDQAYEAAIRDDRHDLLAQ
AMCTELCSDLIDEGVDALHFYTLNRAELTRDVCRAIGVTPQVDLSDVA
>A0A1X7IRQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium pollutisoli|TrEMBL
MNAAAPHHSAKRRFSASAPLDTFDPEESRQVRVPERTSLSFEVMPPRHDADEATIDALLA
TLQSYNPDYISVTSSRNSGWLEGTARFIEKITASTRIPTLAHLACTAGTREELIGWINRL
MDSGVRGLLALRGDLAEGQTEMPAGYLPHATDLINLIQSIEDDQVARFGAGRLAIGVAAY
PSGHEESANMDEDIDVLLTKQRLGADFAITQLFFDAEDYLRFAERARLAGVRIPLIPGIM
PMTSVARLHRMGQLSGLTVPDRLIRRLEAAGPESEYQTGLDLTAELAQTILAAGAGGMHV
YTFNRPDTTTELLDRIGIVPPTTG
>A0A119ATZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia territorii|TrEMBL
MKSIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDNLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAAAATRTICERLAM
>A0A4Y8DN51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIACDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1Z8N8G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. TMED19|TrEMBL
MGRSLEQALASGQLVTTVEITPPLGGDPSRALAAAESLRDRVQAFNVTDGSRAVMRMSSL
ALCRLLQERGLEPVLQLGCRDRNRIALQXDLLGAHALGIRNVLCLTGDPVRAGTQPEARS
VFDLESVRLLQEVQTLNDGMDPTGKPLADGAPSLFAGAAADPQSGXWSGLKSRTRRKAQA
GARFFQTQMVMDTEALRRFCGEIAEPLGLPVLAGVFLLKSAKNASFINRVVPGVHIPQGL
IDRLAAADDPRQEGIRIAAEQVQAYSSIASGVHLMAVKAEESLVQVLDLAGLPKVIAQV
>A0A4Q8QUS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. Leo170|TrEMBL
MTEVAAPPFRTPAISFEFFPPKTEEMERNLWDTINRLAPLSPTFVSVTYGAGGSTRERTH
STIARILNETTLLPAAHLTCVSASRGEIDEIVDRYHEVGVRHIVALRGDPPGGIGTPYYT
HPDGYQSSPELVAGIKKRHPDIEISVSAYPEKHPESANFDADIDTLKAKVDAGATRAITQ
VFFDNDLYFRYLDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTTVPDWFAAKFEGLD
DDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADPVFAISHLLGIRPNGAKKAA
>J0GWT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii WSM597|TrEMBL
MMIAPQSESREKAPLADLLSHYSIEVTSRDLPSLQSMTATLPPGSEVFVAHLPKEDIGLL
VRAAAGLRDAGFVPVPHIVARNIRNRPELDTMLARLSEEAGVRHALVLGGDRDDAAGAFG
SALDLIETGLFQTYGIGRIAIACYPEGHPRIAGAVLDSALTAKVDAAARAGLDLLLVSQF
LFDQKPLLSFARRLRERGVTVPLRVGIAGPASRTKLLKYALRCGVGASLRALRERSEIAR
NVLSGETPEELLIDIAAAEAAEPDLGISGVHFFTFGDPAQSIRWAEQQQPSD
>A0A6N4HB12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. AM16-43|TrEMBL
MNVVDIINKAISERRTRFAFELLPPLKGDGCCGVFGSIDRLIGFDPAYINVTFHREGIKQ
AVRPDGSVEWHVVRRRPGTVGISAAIQKKYGVEVVPHLICGGQSKYDIEDALIDLDFLGL
HNVLALRGDKSQNEKFFMPHPQGHTHAVDLVRQIAAMNRGQFVDGEVEECHHSKFSIGVA
GYPEMHEEAASPEADIACLKAKVDAGAEYVVTQLFYDNARFFDYVRRCREAGITVPIIPG
IKPLSTVRHLTLLPQTFGCHIPEELGREVLRHKDDPKAVREIGTEWAVAQSRELVEAGVP
VLHYYPMGKADNIIKIAKAIF
>A0A1L5PVX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSAERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSRQAAPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPMWATRLGAQVLHKVEHAVKHPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTALLTERLIPCIELETRHRSSWPQWFQAQTP
RQLSPQPAPRTQPES
>A0A2D1TUQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALHEKTFVCVMEFVPKPSAERFAAMQAIMARGHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSSPVPALPHFSGKDRERHHLLAQLQRMDADGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DASKHQEAQAWMNRQPNPKPLLACLMSLTHGRAAMLDHVAGVTVSPSMRDMLEAEAAVSK
AYAQARSVDRLALQVIGVKLMGYAGVHLSGIHELKQLLALEERLEHWQAQLHSLEQWAPA
WAASWQVHGLPAVVFHPPAASWRQGESKVSASSTEKARYHLLHAFHALLFSRNNWLSKAF
GWAVRQPLWASASGARVLHGVERAVKRPLLGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTSLNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVHTRHRSSWPAWFAAQAP
QRLKACSKPRTQPES
>A0A6P2BWS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trebonia kvetii|TrEMBL
MRASRQETARRSWNPRTLRSAVPAEQPRCLARPGWPETQHSSPRNAVSTVEPHSVGVTNI
RVVASDAWAVAAAACPKHMSHGPCAGVRADGACEVPGVGRCSYLDVPDRDWPYADVLIPA
PDPGAAIPDVAGAWPRSPAAAGFLATAATRPVVVADLVAPALSADGVRACAAEIVGFADA
CLTGDHPGARVQFPPSYRARLLAGEGVAAWAGINCRDRNRVAIEGEIAACADAGVAGVHC
VTGDHPGTGHRPDAAAVFDLDSIELVELASMSLALPARPLCSVAHAPAAPPAGKRLARLL
AKIDAGADVVFVDHCGGAGPLAEAVAALREAGFSGLVLCCVPVVTSAGAAEVVASFAADR
LPPGYLDAIMSAPDPAESGVTAAVHFAEAVLAVPGVDGVNLSAGAGPGQELAVTRAMAEV
GRRVLGAPAASRPRPAGGVS
>A0A1G7I449|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fontibacillus panacisegetis|TrEMBL
MKPDLRKRWENEVLVGDGAMGTYLYQLGSPVGISCEELNLISPDVISDVHRRYIEAGSQL
LETNSFSANYYKLSKFGLESQVEEINRAAVRIAREAAGSEGYVAGAVGSIRGGKRVNVSV
QEMGTYFEQQISALLTEGVDALLFETYYDLAEMRIAVGRARKLTQVPIIAQFAVDQVGRT
MDGYKISEAFSILQDEGVDVFGFNCHSGPKGIMSVMSGLKGPLNVPLSVFPNAGLADYVD
GEYVYGASPEYFGECALSFANLGARLIGGCCGTTPEHIAATASALQGYKAESLSQGKPLP
EVREAIVVNSDMAVKEANNASNGASSASGITELVKERHTIIVELDPPRDLDISKFMEGAA
ALKAAGVDALTLADNSLAVTRMSNMALGHLVLTELGLRPLVHIACRDRNLIGTQSHMMGF
DALGIDHVLAVTGDPARFGDLPGASSVYDLTSFEIIRMIKQLNEGVAFSGKPLKQKANFV
VGAAFNPNVKHLNKAVERLEKKIASGADYIMTQPVYDPELIVAIKEATAHLDIPIFIGIM
PLASGKNAEYLHNEVPGIQLSETVRKRMEGLQGQQGRDMGVEIAKELLDTAMEHFNGIYL
MTPFMFYDMNVTLTNYVRERSKAMAPHLSHSS
>A0A5F0WCS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMDRAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQVARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQATPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALEARIEHWQTQVQSLEQWAPA
WHASWQMPGLPAVTFHPPQAGWRLGESRVDASLKEKARYHLMHGMHALLFSRRNSLSKAF
GWAVRQPLWGTRVGAHVLHTLERSVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A1L7NJD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSTERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALAAFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQLARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQPTPLPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
VFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQTQVHTLEQWAPA
WQASWQMPGLPAVIFHPPQAAWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRRPLWATRVGAQVLHKVERAVKRPWVGCDTCGRCRLEDTLYVCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFQAATP
RRVSPQPAPRSQPES
>A0A3P5X2J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Filibacter tadaridae|TrEMBL
MSLNLLDTLKERILIGDGAMGTLLYSHGVDLCFEELNLTHPDQVLHIHQAYIEAGADIIQ
TNTYGANYIKLARHGLEDSVKEINKAAVQIAKKAAGEDTFILGAIGGIHGSRTSTGTKDE
IKRSFREQLYCLLLEGVDGLLLETYYDFDELTTVLKIAREETDIPIITNVSMHEAGVLQN
GLELADALLQLENLGADIVGINCRLGPYHMLKSLESVPLMKRALLSVYPNASYPGYKDGK
LFYENEPEYFEKFALNFRKEGISLIGGCCGTTPEHIRALVKGLTIREPIQEKLVKKKVAK
VAASESKLKESQSPTLLETVKKRHSIIVELDAPKHLNTTKFFEGAQALKDAGVDAITLAD
NSLATPRICNASMASLVKQTIGATPLVHVTCRDRNLIGLQSHLMGLHTLGITELLAITGD
PTKIGDFPGATSVFDVTSFELIKLIKQFNEGVSKSGKSLQQKTSFTVAAAFNPNVRHLDR
AVERLEKKIEAGADYFITQPIYSPERIIELYEATKHIKAPIYIGNMPLTSSQNAEFLHNE
VPGIKLTDQVRARMALSNGNREQSTKEGLQVSKELIDVALEHFHGIYLITPFMRYDMTVD
LTKYIHSKVDAIVAREVVRA
>A0A4U2EF13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. F13|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPTGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A348AFI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomusa anaerophila|TrEMBL
MSEAAALRAPSLKTESKLEQLYAQGHFIVTGELGPPQHSDGHDLEHHAHELKDIVDAFNL
TDNQTAIVRLSSIAAGVHVLKGGGVPIIQMTCRDRNRIAMQSDLLGAYSLGICDVLCLSG
DHQSFGNHPTGKNVYDVDSIQLISMVKKMRDDKQFLSSAPIKAHEPRFFIGAVENPFGDP
FEFRVTRLEKKINAGADFIQTQAIFDLEKFARFMEMAVARGLHQRAKITAGILPVRALRA
LQYMQNDVAGMEIPDSIIQRMKKAVEGKDKAEAKAAGEKEGIQIAIEMCNELKKIPGVAG
IHIMPVGWEAALPEIVKGAGFLPRPKA
>A0A4R1HR11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia endophytica|TrEMBL
MTTPNSSLTVTDRISLDRGRPFFAVEFFPPKDDQGEADLWRAIRRLEPLDPAYVSVTYGA
GGSSRDRTVRTVGRIATDTTLVSMAHLTAVSHSVTELRHVIGSLAANGIRNIMALRGDPP
GKDPLDEWEPHPEGLMYADELVELCKQSGPFCVGVAAFPYGHPRSADLESDTEKLVGKFR
AGAEFAVTQLFLEPDGFLRLRDRVAALGFDQPIIPGIMPLTSEKTFHKGPELSGSPLPEA
LVKRLEPYTGDQKTFRAAGMEVTGELCERLLAEGVPGIHFYSLNRSTATTELVDRLGLLA
PSPAPTA
>A0A1H2EDQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula phenolica|TrEMBL
MKTESKLEKVLASGNLAVTSEVGPPRGAIPEIVREKANLIKDHVDAVNVTDNQTAMVRMS
SWAAGVIIKQMGLDPILQMVTRDRNRLAMQSDIIGAYSLGINTMMCLSGDHAKFGDHPMA
NGVFDLDSVQLVQTVKKMRDEGKFQGGADIKTPPKMFIGAAANPFADPFELRVMRLAKKV
RAGADFIQTQCIFNLDKFEKYMEMMCDRGLDEQVHLLAGITPMKSAGMAKYMKNKVPGMD
VPDEVIKRMEGVSKEEQPEEGIRIAVESIQRLKEVKGVHGFHIMAIEWEEKVPQIVEKAG
LFPRPVL
>A0A532U375|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium B3_Chlor|TrEMBL
MKSGSNLEKVLTEGHFAVTSEMGPPKGTSADFVRKTAEHLKHCCDAMNVTDNQTAIVRMS
SLAACAILRQMGIDPVMQMVTRDRNRLAMQSDILGAVALGIRNLLCLTGDHQKFGNHPTA
KNVHDIDSIQLEQMIKTMRDDGLFMSEDKISGDVPIFIGAAANPFADPFEFRVLRLAKKI
KAGADFIQTQAVFDIPRFAKWMEMVRDQGLHEQVYILAGLIPMKSVGMARYMKKYVAGLM
IPDELVERMAGTSDAKEEGVNIACELIEQIRDIPGVRGIHIMAVAWEEIVPGIVERAQLL
PRPIV
>A0A1P8WYJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. QXT-31|TrEMBL
MTTTSLPSQSEARRAAASPLFAGLAGDIGISFEFFPPKTEKMGETLWESIRTLEPLGPNF
VSVTYGAGGSTRERTHATVARIVQETSIPAAAHLTCVDASRDEIAEVAQAYWDAGVRHIV
ALRGDPPVQGEKFQARPDGYSCAAELVSGLLEIAPFEISVAANPETHPEALSAAADIDNL
KRKLDAGATRAVSQFFFEPDTFFRFRDAAAAAGITAPILPGIMPVSNFGAIIRMSAMCGT
DVPRWLAQLFDGLDDLPAARQLVAATTAAELCRRLYAGGVRDFHFYTLNRAELSYAICHM
LGVRPAAPATEKAA
>A0A1Y3LLT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFETDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1Q7YU43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenarchaeota archaeon 13_1_20CM_2_53_14|TrEMBL
MKLSERAKYHTIVTAEVIPDRVVPAHLPLLDGRVDAITIPALRNGENDPSYPSEFRVTPQ
TRSVASAVIVKKTGFEAVPSLTCRDFRRSDLPLLPVLFKKGLENFLVVFGDPYPNYEIKT
YDFKRAEDLIRGIRSVFDGQRPCIGAVTNQYALDREKEISRTLSKVDAGADYLVTNSAFD
DYYVLDYIDALRSSGLKVPIFVQLSIPHGLNNLLFVSRRFGIPVPESVKETVSRDPLGGG
VQVIARAFAGLRNEVSGIHFSYLFRSHNPIPTYTHLLDAIETDWQLVGSLQATLRT
>A0A8J5IF72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora aleatoria|TrEMBL
MGKIIESIRSGYSARADDASARPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGAERWSPVEGGLSNAVDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIQWIADCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPEKVLTALDAIKNDDAAVRRYGTQLAVETCQRLLAAGVNSLHFYTMNLAAT
VTQVLEGLQLLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRTELWGTPQTEEDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAAIRENLQWLNSNGFLTINSQPRVNCTPSSDPSVGWGGDDGVVFQKAYVEFFVA
PEKMAHLVKVMRRDYPQLSFHALNRRGDEHRNTPLHSVTAVTWGVFPGIEIVQPTVVDSD
SFAAWKDEAFELWQTQWASAYPEGSHSREVIQHIYDTYFLVNIVDNDYANDDSDIFSIFT
RIITEAMDKEQLRARVLELETRREKMFDTLASFQSLQEELNGELRAAHSELAGVRGENLQ
LKEKVRQLQAQLALASL
>A0A7H8MAE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. NAK00032|TrEMBL
MWALSRRSGSGLVGFEVVCEVEPPTRPDLRKVRHQIGVLSPVADSFLIPDNHIGRATVSS
VAVAHEVQAMGARGIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVYGDKPSAGGRTSEL
TVRAMMEEARAASADDVFDGCGAFQVGVTSGLRKVPEWKRAADFTFVQVSYSVENLLRWR
ESVELEGPVYAGVMVLASAGMARNLAAAIPDIDIPGELVEAVERDRGAGVAAACEQVLAI
RDSGAFDGVHLVPVSRYREVAARLEGEL
>A0A5N6VM80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus transmontanensis|TrEMBL
MHIKEKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAAEGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLEAL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIKDLSRLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLIE
LNHRGILTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDSWYLVNIVNNDFHNTYDLFELFKDLNVRDFDVEVAADDADLK
SQENETAETAAN
>A0A2A9HFT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium (strain G233)|TrEMBL
MRFLERLAAGRFAVALEITPPQRHLPKVLLRRARLLGDAADAVNVIQRPDRQSSLAASLE
LRAAGIDPVWHLAARGMSAAEVTAAAEAARAGGIEQVLCVAGDHAANGAPGVTVREAIGL
VRAAMPGVTIGATLNQYARDPARARRNLLPKLLAGATYVQTQPTFDVGGLEAELAAVRPE
AEGVAAVAMAMPLLTAEAGERIAHRLGLELPGRLRDILSAGDTEAAWAYFRETVARLVES
PAVQGVAIMTFEMDPPPEMGERIVAALEAAGAR
>A0A349JET3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcoleaceae bacterium UBA11344|TrEMBL
MNRFRTACTTPGEFIITAEVTPPKGGDMTHTLAMAQQLKNRVHAINITDGSRAVLRMCPL
AVSAILLQHGIEPICQVACRDRNQIGLQADLMGAQALGIRNVLALTGDPVKAGDHPKAKS
VFDFEAVRLLQTIQKMNGGTDWNDKRLTDGVTDLFAGAAVDPQSPSWSGLQSRFEKKIEA
GAQFFQSQLITDFELLDKFMHQIAAGCNKPILAGIFLFKSAKNAEFIKKYVPGVHIPQET
IDRLAKAPEPLQEGIKIAAEQVKLARQICQGVHMMAVKREDLIPQILDLAGIEPVS
>A0A1V6QSB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium solitum|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEAAENGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNTDVDQLIDHLKEKVDAGSSF
VVTQMFYDAENFIEWLKKCRAKGITIPIIPGIMPIQTYASFIRRSSWTKVKVPPQWMEAL
EPVKNDDSAVRDIGKTLIADMCRKLVAAGIKHLHFYTMNLAQATQLVLKELDLSPSDESP
IQRALPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISDIFVNFLTGKLDRLPWSDSPITTEAHDIQEDLLN
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLLDELITRIEKND
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCHDAASPSRKLIQHVMDDWYLVNIVDNDFHRSNAVFELFNGLEIKDLNVEVAGKPLTNG
HAEQNGVAAN
>A0A2G2BE90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinosulfonomonas sp|TrEMBL
MVTPRISFEFFPPQSLMASFRLWDTVQVLAPLNPEFVSVTYGAGGTTRDLTHDAVTTIHK
NYGLNVAAHLTCVNSTRAEILAIADGYAAAGVTDIVALRGDAPNGADKFTATDDGFANSI
ELIXTLADTGKFNIRVGAYPEPHPDSANMAADVDWLKRKIDAGASSAITQFFFEADTFFS
FRDACAAAGITAPIIPGIMPITSWTGIKKFAAGCGASIPTWLDDAFNAAIRDDRTDLLAT
AVCTELCSDLIDGGVEDLHFYTLNRPALTRDVCHALGVAPDVSLQNXA
>A0A1G0M5F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium GWC2_58_44|TrEMBL
MGSSFLERIAGGVLVGDGAIGTMLYAKGVALEANFEHLNLVRPELVLELHREYIAAGAQV
IETNSFGANLVKLAAIGLGGKVAEINRQGALIARRAAHGHDVFVAGSIGPLGRGKGELTT
DEVRECFRAQAAALAEGGVDLLILETFAELEELEWAVAAAKETGLAVVSNLAFGEGSRVA
GGIEAEAAALRLVAAGADLVGANCGAGPLAVLATLKKIAAVTELPLAAYPNSGFPEYLDG
RYIYRATPEYFAAKAAEMVAAGASLVGGCCGTTPDHVRSMARRLRGVRPAPRTASRAESR
SPAAESVTGAGTGFLAGWGREMVVTVELDPPKGLDCAKVLAGSRALKEAGADAINLAENP
LARVRMGNLALASLVRREVGIEVIAHVTCRDRNLIGLQSDLMGASLLGVSSILAVTGDPA
SLGEEAGASSVFDLNSFTLIKLLSDLNRGVNALGSPIGSGTGFTIGAAFNPNTQKMESQV
ARLARKVANGASFAQTQPIYDLERLGQMLEQTRHLGIPILPGVLPLVSGRNAEFLHNEVP
GIVIPDEIRERMAGRVGEDGVREGLAIAREFIEAAIGQVGGFYLIPPFGKYQIAVELVKF
IKEHATRRSG
>A0A836P8M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIANTIH
GEYGIPAVAHLTALYSDEAKINEALDMFEAAGVSAVLALRGDYIDGEEPVGRFNHASDLA
AYIHDRKPDLNVFGACYPEGHYSAASLDEDIGNLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGAKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGII
YASDQIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFTVE
>A0A2L1VMG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter nosocomialis|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGK
ARDIQDFERFLDQAESANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKNNYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHIDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLELNVLEELWNSLWQVTSGKEFSPEITRFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALVAKVLLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVEQT
EILKEKLIPTVAIETRGTSSWKNWYLATEA
>A0A8B9IAL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anser brachyrhynchus|TrEMBL
GSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDRWFSLEFFPPRTANAAVNLIS
RFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDI
TGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDICVAGYP
KGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFLKFMKDCQAIGITCPIIPGIFP
IQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSMCRELLDSGVVHGL
HFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRT
QEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVFTCY
ITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNINGKPSTDPIV
GWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNYHIVNVKGQNITNAPDLQPNA
VTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYL
VNLVDNDFPLENCLWQVVDDTFELLNSPAQNQQEAVKRLATQ
>A0A6G6X378|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nordella sp. HKS 07|TrEMBL
MSKPELKVSFEFFPPKPEASESFWKVINKLEEMKPLFVSVTYGAGGTTQERTLGTVNAIR
ERTSLIPAAHLTCVGAPREDVDKVVRGYWDAGIRHIVALRGDPPGGVGGRFVPHPQGYRN
AADLVRGIREIAPFEISVAAYPEKHPEAVSIEEDLAFLADKAEQGARRALSQFFFNNAAF
LRFRDRVFARGIDIELVPGILPITNFARVKEFAAKCGAFLPPALGQRFHGLDADPETRNL
VAAMVAAEQVDFLRREGVNSFHFYTLNRADLVYAICRVVGLGEHAEAA
>A0A183CHN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Globodera pallida|TrEMBL
MLASLINDRHRQQGQCSPFFSLEFYPPLKDQPKNMSDFFDMLNYLKQAQPLFVDITWSRR
NDPGNLCKLNSSSAIAIATADIFGKERTMLHICCNDHTKAESVSHVEQTLGHGIPNIMAL
RGDDLPEATPTLNGQLLNTKHYATELVKWTRQLEGARGICGDNRLTVAVAGHIFSPIKTV
SYGQCMEYLRAKVDAGADFIVTQFFLDANLFEQFRVDCRSIGISVPILPGILLFKSAASL
RKIAELSNVPIPQQISQTLKQIGSDTVAVQNYAVQLAYDMCRNIFSAGHTTGIHIFTLNQ
RDMCGKLLKRLGFWPTMNLEISAKLNDNDETNVIKKEHLKISLNGTPTRKSA
>A0A0Q0Z864|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium lowii|TrEMBL
MSTAHLYSEYRPGVPAATPTVSFELYPPRNPSRGSGVWAGISRLIDTAPDYVSVTYGAAG
KRTDTRDRSVQVLLNVLDRHRNLPAVAHLTCLGSTRAELTLIVRLLLRAGIRDFLALRGD
PPGGDPNYLPAEGEPARAVDLVRLIREIAAEELPLGVGRGYNGAGATSAPRPEDYVSIAV
AAYPAATGQGRANDIAALVEKERAGADYAITQVFYSPHDYDSMVRELSLAGGRLPIVPGI
MPLHDLKRLRAMEKLAGIPVPKHIERIFSQATSPDRLVRETLSATVDVIGGVLDAGAPGI
HLYTFNRPRPTLDILEYLRASGYLGRTAGVRTPREPEVDTELVSLALHRMTPSYY
>A0A1E4HKJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. SCN 72-86|TrEMBL
MSSSPPPRATVVDRLDVGRPVFSVEFFPPKDAAGEAQLWGAIRRLEPLDPAFVSVTYGAG
GSNRDRTIRTTERIASDTTLVPMAHLTAVSHTRAELRHVIGSYAGAGVRNVLAVRGDPPG
DPLGDWTPHPDGLTYADELVTLVRSLGDFCVGVAAFPYGHPRSTDADTDFERLVAKIRAG
ADFAITQLFLEPGGFLRLRDRLDAAGCHVPLLPGIMPLTTVRTLHRGPELSGAPLPDDLV
ARLDRYADDPVAFRAAGMDATAELCEKLLAEGVRGLHFYTLNRSPATVELVGRLGLASAR
>A0A1H0S3S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas extremorientalis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISNMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1A9RYN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eikenella longinqua|TrEMBL
MQNNTLSFEFFPTRTPEGREKQKITRKQLAQYQPEFFSCTSGAGGTTREGTMQTIRDILA
EGMAAAPHIPCVGLDAGELTELLQEYKNMGIRHMVALRGDIPSGMGLGTTGLHHANELVE
LVRRQFGDWFHIEVAAYPEYHPQSRSAEDDIQSFVRKVKAGADSAITQFFFSADAYFRFL
DDVRGRGVDIPIVPGIMPIANFSKLARFADMCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCARLLRHGAPGLHFYTLNQAGLSSTICQRLGY
>A0A1V3R8N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus sp. A40|TrEMBL
MKITEHLKNANSTLFSFEILPPLKGQSLKELMEGIAPLMEFKPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFHVDAVPHLLCGGFSKEETENALIDLNFIGVDNV
LALRGDAPKTEGRFIPEAEGHSFASELVEQIVRMNNGRYLHEETENSFHTDFCVGVAGYP
EKHFEAPSLKFDLKYLKEKVDKGAEYIVTQMFFDNKKFFDFVAKVREAGITVPIIPGIKP
IATLGQITNLPRTFFLDLPDALTDELEKCKTNADVKEVGIAWAIEQCKELIEANVPSLHF
YTMSKADTTYKIAKAVF
>A0A5N6ZF11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus coremiiformis|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
ARRSLELAEICQRQLQLTTCLHLTCTNMSRVLVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRQKYGDYFCLGVAAYPEGQAVDSFHDVQDPKKDLPYL
VEKTQAGADFIMTQLTYDVEAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVKIPPHILSKLEEVKHNDDFVKHIGVDIISNIVDGIRDIPHPRPRGFHFYTLNLEKT
VSFILERCDLIPPYSDDFDAVEDGGDISALDGAQLRSLTRRRASSINSLPHNRVIVDKLQ
VSEGSSKASVSHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVPSSVAHRIWGFPVSREDISTLFRRHVSGELHMVPWSEGGAEEGSP
GLNAETDVIRSELLQLIDGNGWWTLASQPAVNGVRSDNPVFGWGPPREGFVFQKPFVEFF
CPSKDYQSVVKPLLLKHGHEKLAWFATNVQGNFESSLPAQTSDADPIEMNPNNVNAVTWG
VFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNETKDDVWLVCVVG
QDFGAGTEMGSEEEENEKKWMWSVLANAK
>A0A448KQ13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter upsaliensis|TrEMBL
MCSFSFEVFPPRRDETIKNLDAILEDLGRLSPNFISVTFGAGGSINSKNTIEVASLIQEK
YQIPSIVHLPCIHSSKEKITAILKECKQRGLNKILALRGDVCEGLEKSKDFSYANDLISF
IKKQENFEIYAACYPEKHSEAKNIIEDIHHLKNKVNVGTDKLITQLFYDNEDFYAFKQNC
ALSGIKVPIYAGIMPITNKRQILKISQLCGAKIPTKFTKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKTKAAIRIYEAVKHLPKEENEAKNVL
>A0A6I0E7N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp|TrEMBL
MPMVSERKSRLLGAGEIDVSFEFFPPKTEKMEEQLWSCIERLAPLRPEFVSVTYGAGGST
RERTHNTVARIIRETDLKPAAHLTCVTATKEEVDSVARAYWDAGVRHIVALRGDPAGGPG
TKYEPHPGGYINAADLVGGLKRIAPFEISVAGYPEKHPESPTLAADMDNLKAKVDAGADR
IITQFGFDNAHYLRFLERARAAGIWVPITPGIVPIHNFKQVAAFAARAGASMPSWLAHRF
EGLEDDAATGHLVAAAVATEQVMDLVDEGVKKFHFYTLNRADLAYAICHLLGLRPHTSPA
PARARAAG
>A0A7E6DPW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllostomus discolor|TrEMBL
MDLPNPEVLPAGHCWPSLGMRALEAGIVSLSVPPSISKDSAMVNEPRGNSGPGTHWEGSS
CGIESSKDSLKGSSPGLDPERRERLQEKMKRKMESGDKWFSLEFFPPRMAQGAVNLIAMF
DQMGAGGPLFIDVTWRPTQDPGSDKETSSMTIASTAVNYCGLETMLHMTCLCQSREAVTG
HLRKARRLGLKNILALRGDPPGEQWEEEEGEFSHATDLVKHIRSEFGDYFDICVAGYPKG
HPDAVSFEDDLKHLKEKVTAGADFIITQLFFEADTFFLFVDACSKIGITCPILPGIFLIQ
SYHSLRQLMKLSKLEVPQSIRDVIEPIKDNDDAICNYGIDQAVSLCRKLLASGLVPGLHF
YTLNRLKATTEVLKRLGMWTEEPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTRD
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKAPREELLKMWGEQLSSEKSVFDVFVRYLS
GEPNQNGHPVTCLPWNDEPLAAETSLMKEELLRVNRRGVLTINSQPRVNGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWVERWGKLYDEKSPSRRIIQHIHDNYFLVN
LVDNEFPLDSCLWQVLEDTLELLNRPTSE
>A0A7V9RHV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIDEILQRDEPTFSVEFFPYKTDKGREQLFETVEVLSKLEPSFFSVTYGAGGSTHDRRR
TLEITKTIRDEHGVEAMAHLNCVGESAEGLRAVVDEIASAGIENVLALRGDPPAGQPDFV
QPEDGLGSAAELAQMINGSPHELAIGGACFPEVHPEAAGLDKDLAYLKTKVDAGASFLIT
QLFFDNQVYFDFVPAARAAGIDVPIIPGIVPIVSLEQVRRTCKLCDATIPEPLEAALESL
GGDERAEYEFGIAYAAQQCSALLAHGAPGIHFYALNRWPATKAILGALRAARPWDSAPSE
PLALPAA
>A0A1I1EVW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parapedobacter composti|TrEMBL
MKITEHIKNANGKTLFSFEILPPIKGQSIQSIFNAIDPLMEFNPPFIDVTYLREDYIYKQ
HPNGLLEKVAYRKRPSTVATCAAIINKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARKSDSSFIPTPGGHAYASDLLQHVVNMNNGRYLHEDMENSERTDFCIGVAGY
PEKHFESPNLDTDFKYLKMKVDLGADFIVTQMFFDNSKYKAFVDRCRANGIHIPIIPGLK
PLTGSKQLVSLPKTFHLDIPLELSEAVLACKSEQEVREVGIEWMIHQCKELIAMGAPVLH
FYTMGNPNPTKRIIQAVF
>A0A2T2PCC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynespora cassiicola Philippines|TrEMBL
MMEKVTDKINALPEGANYFSLEFFPPKTSMGFANLQTRLERMSQALRPLFVTVTWGAGGS
TATKSLELAEICQRQLGLTTCLHLTCTNMNRSLVDEALDQAKALGIRNILALRGDAPRSE
EYRDESQPPEEDSNKDFTWAVDLVKYIRKQHGDYFCIGVAGYPEGHADESHPDHQDPNFD
LPYLVEKTKAGADFIMTQLFFDVKAFDDYEAMLRGHESGVFKDIPIIPGLMPIQSYQILR
RTTKLSHASLPDDILARLDVVKGDDELVKQEGVKILSEIVGHIKARPSAGRRGFHFYTLN
LEKAVSHILEDCHLIPRPMIESDEEAIETTPAINLLPPDGARSNRERRRLSSINSGPRNR
VIISQPSRSSNVSYEAPETEAGIPKGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGYPVEQADISNLFKRHLEGQLEALPWSEQGLSP
ETNTIAKELLALNSKGWWTVASQPAVNGLKSSDPIFGWGPKNGFVFQKPFVEFFLPSADW
EKLKPRLDAHEQVTYFAGNAKGDFEASNEEGVNPVTWGTFTGKEIVTPTIIEAVSFRSWL
EEAYSIWKEWQRIYPAKSPTSKLLHETRNDMWLVNVIWGDYVEGQGFWEFLMA
>A0A090QRL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium aphoticum|TrEMBL
MGYSYASHLDALNQNIADLDGNINVSFEFFPPSSEQMEQTLWQSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKEQTGLVAAPHLTCIDATRDELRTIARDYWNNGIRDIVALRGD
LPPQGGKPDMYAADLVALLREEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNMKQAKRFALANNVKVPGWLEKQYE
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLACAPSRVRLL
LLSAVISKDRYKPSAVIS
>A0A2H0QLS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrio sp. CG11_big_fil_rev_8_21_14_0_20_39_38|TrEMBL
MKVIEHLQNARGPLFSYEIVPPPRGRTVKDITEIVKAVEKFNPPWIDVTAHSAGASYNER
PDGTIERKISKKRPGTIGICGIIQNRFKIDTVTHILCNGFTREETEDALIELNYLGIENL
LALRGDGLNYNKKISKDRSVNVYASDLVEQIDGLNKGHFLDNLHNSEALDFCIGVAAYPE
KHFEAPNLKVDIANLKIKQDKGATYAVTQMFFDNDHYFNFVKACRAEGVTIPIIPGIKIL
KNTKQLQTIPKNFYINFPDALVDETLSNPNHVVDIGIEWATKQVQGLLEGGVPGVHFYIM
NDTDSVVKVVDKFYKQV
>A0A2Z2IVZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium striatum|TrEMBL
MTPRLSASAPLDQFSEVSVKPRQRTALSFEVIPPRNDADASTTAELLRVLQGYNPDYIAV
TSSQRSGWLEGTAAFIEQISRTTSMRPLAHLACTAGTREELIGWIDALVDAGVRGLLALR
GDLPEGGMPTHYLQHADELVRLIRHREAGQAARFAAGSLAVGVACYPNGHAESANLDEDF
DVLLAKQRLGADFAITQLFFDAEDYARFAQRARLAGVRIPLIPGIMPMTSVARLERMAKL
SGLQVPPRVRAALAAASTPDEEHEIGMELTAELTRSVLRSGADGLHIYTHNNPHITQDLL
NRIGVHP
>A0A7Y2DIV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pricia sp|TrEMBL
MKITDHIKKAKGETLFSFEIIPPVKGHLIQELYDNIDPLMDFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNI
MALRGDAMKDEKYFEPTKGGHPFAIDLVKQVHSLNCGNYLHDTVESENCANFCIGVAGYP
EKHLEAPSLKSDLKRLKEKVDAGAHYVVTQMFFDNQKYFEFVDEAKKIGIDVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVDDCATNKEVRQVGVEWAIQQSKELKAAGVPVLHF
YSMGKSDNIKAIAEAIF
>A0A8J2HU22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria atra|TrEMBL
MHISQKLAQAREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDDALRDAYNSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGGTF
IVTQMFYDTDLFLEWVKKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTRCNIPKHWTEAL
EPVKNDDVEVREVGKHLVADMCRKLIDAGIMHLHFYTMNLAQATRMVLEELDLLPDSESP
LEKPLPWRPSLALNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPMSIRDLSELFVRYMEGKLDSLPWSEQPITTEAGSIQDDLID
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEHISEIITRLERDP
EFTYYAVNKNGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVLQGIVDTWYLLNIVHNDFHATRGIFPIFDGLEVKDMDKPLVNPSVDS
PGANGEEATKAVNGDSHTNGTNGEQAGPRKEENPSLIDAAKAAAVEVTNGMRSLAMSN
>A0A674CF17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmo trutta|TrEMBL
LANNTWRTCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTESGDHWFS
LEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LESILHLTCCNQTKAKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYATDLVKH
IRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKMDAGADFIITQLFFRADTFLKFVR
DCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPDEIMRVIEPIKDNDAAIRNYGIEQ
AVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWNEDPRRTLPWAVSAHPKRKVED
VRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMW
GEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKNELDKVNRRGVLT
INSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIV
NVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQWAKLYED
ESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPQEEQPAEQPNDEQSD
KEQPGK
>A0A6I3SJ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heliobacterium mobile|TrEMBL
MTRIAVELVPRSEEDLISELELIKKEFPEVNGINVPDLLRFDLRSWDACTVVKRYYPTAI
PHLRAIDISVQDPLPMMETLLKNEITEVLVLTGDPPQSMTRKVYPTTSIDMIRKFKKELP
HIKVYAAIDPYRDSLRKEYDYIRRKIDAGADGFFTQPFFDLRYMEIFAELFGGLEVFWGV
SPVTSEKSVSYWETKNHVVFPADFQPTLAWNSDFARKALAFARETKGHIYFMPIRTDLKD
YLSQVFAS
>A0A2W2C751|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aestuariivirga litoralis|TrEMBL
MIAFAEDVSGITVSFEFFPPKGDAQDSFWQTIRKLETVNPSFVSVTYGAGGTTRDRTLET
VRRIAGETTLKPAAHLTCVGASKAEVNATVNDFAKAGVRHIVALRGDPPGGVGTRFTPHP
DGYRNAADLVRGIKELGDFEVSVSAYPERHPESVSIEEDLAFMADKAEHGASRAISQFFF
HNPFFLRLRDRIAARGIDIELVPGILPITSFARVSEFAAKCGAHVPPALATRFAGLDDEP
ETRNLVAAMVAAEQVDALRREGVKHFHFYTLNRADLVYAICRVLGLGAEKKAA
>A0A375AKY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerochaeta dissipatitropha|TrEMBL
MQVIDILNQAKRPLFTFELVPPLKGGDVQTLLETVRQLSRFEPAYINVTNHQQEVVYIER
PDGLLERRTVRKRPGTIALSALIQYTFNIPVVAHLICGGMDQDELEDALVELNFLGIENV
LALRGDPPNGEKRFVPVKGGYEHSSELVSQISDLNRGKYLDQDLQNAQKTHFCTGVAGYP
EKHAEAPNLERDIEMLKYKVDCGADYIVTQMFFDNAVYYRFVDACRKAGITVPIIPGLKP
IGSKRDLATIPQTFHVDFPSELVELLSKATKLSEIREIGVHWCTLQTKDLLAHGVPGVHF
YTLGKAESVASVVRSCY
>A0A0S8JGP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium SM23_57|TrEMBL
MTFKEKIESDRFILCGEIGPPQSCDGDVIRAKSKHFKGYVDAVNITDNQTAMVRLSSIAS
AKILLEEGVEPIMQMTCRDRNRLAIQSDLLGAAALGIRNVLCLTGDYQTFGDHPEAKGVF
DLDSIQLIATIAKMNRGFLLSDFEMKKAPEFFIGAAANPFAEPFEIRLIRLYNKIKAGAH
FIQTQPVFDLEIFTRWMDRVVEMGLHEKTAILAGVMPIRSVKTLIWLKENLSGVKIDDIY
INRMQHARDPKEEGVKMSVDIIQTLKNVKGVRGIHLMPVMWESITPTIIKEAKLNMTN
>A0A6L8XQC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia wexlerae|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEQAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A8J7JTF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oculatella sp. LEGE 06141|TrEMBL
MFDTNHHASNTWLPAPSSRFRVAAQSGEFLITAEVMPPKGGDPSRMVQMARQLKDWVHGV
NITDGSRAVLRMSSVAASVVLLQHGIEPICQVACRDRNSIALQADLMGAQALGIRNILAL
TGDPVKAGDHPSAKGVFDLESVRLLKLIGSLNRGIDLNHQPLSDGPTDLFVGAAIDPQCA
SWSGLQSRFERKLEAGAQFFQSQLISDFDQLEKFMNQIALDCQKPILAGIFLLKSAKNAQ
FINRNVPGVTIPQHIIDRLDRATDPLQEGIQIAAEQVQLARQLCQGVHMMAVKREDLIPN
ILELAGIAPLAKAEVVR
>A0A1U6GM36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. DAB_AL43B|TrEMBL
MTKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALCV
RGNTDIAPHMSCIGDDKAEIAELLDLYKSLGIKRLVALRGDLPSGQVGMGELPFAVDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFESDIDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTIAQPLVAGIMPITNSSNLVRFADSCGADIPRYVRKQLADFGDDSKAIREF
GFEVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLSA
>A0A2C9JU58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Biomphalaria glabrata|TrEMBL
MPDIKNPEAIDGNSASEQNEHSINGTNHTSNSDHECAVTKPQNGANILSRKPSDSSSISS
SPGESRAASPVSSRKKYVSLIERIRKRIQGKTPFFSLEFFPPRTQSGAMNLISRFERLSE
GHPLFCDITWHPAGDPSNTEKPTSSTCMAGVMLNYCGIETMLHMTCVGMSTDTIKENLHK
AKDLGIRSILALRGDLPEGDDHWKETEGGINYATDLVKLIKEEFGDHFVICVAGYPAGHP
DCRSYHEDLQHLKEKVDAGADFIITQLFFKPETFLNYVKDCRKLGINVPILPGILPIQAY
QSLRHIVKLSKLEVPLEIITAISPIKDNDEAIRKFGIDHSVDMCRALLKSGIVPGLHFYT
LNREVAVKEVLKQLGLWNEKAPRTLPWKKSANHARCDEDVRPIFWRCRPNSYVYRTSEWD
EFPNGRWGDSRAASFNDLKYYHLFYLKSQSPKEELLQMWGEELTCEEDVWSVFVNYLTGQ
PNKQGVKVKRIPWDDDEIVAETSLIADKLACINKRGVLTINSQPRVNGASSTDPIVGWGS
PNGYIYQKAYLEFFTSKESVDALKHILPRYPLVNYHIINHSGAADYTNCDEHQPIAVTWG
FFLAKKFFNQL
>A0A3N1H563|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix texasensis|TrEMBL
MTSVVERLHGGSPVFSVEFFPPRDEAEEIILWRAIRELEAFDPAFVSITYGAGGSARDRT
IRTTGRVAQETTLLPMAHLTLVDHSVAELRNVIGWYAAVGVRNILAVRGDPPGDPNGEWL
AHPEGLTYAEELVRLCRELGDFCVGVAASPYGHPRSTDLDSDTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAARGCDTVLIPGVMPLTTPRTLAKTVELSGSSVPDSVARRLDPYA
DDPAGFRAAGIDLVTEVGERLLAEGVPCLHFYTFNRSKATREIVGRLGLVPARAA
>A0A373JAK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium AM10-47|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELLEEAKTYLQGVHAVNVTDNQSSVMRLGSLAM
CKALKDAGMNPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVGLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAIFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKVPELLKQAEI
>A0A520SAR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halieaceae bacterium|TrEMBL
MTDTKQAVINLFSDFTVETTPNSASKIPDFNARLRNDTPVYVTFLPGSDVYETVTVAKRL
RGEGFNPIPHIAARSLQSEDMLSEILKRYVGEAGVEHVLTIAGGVDNPLGPYDSSMAVLE
SGLIDKAGISKVSVAGHPEGSPDITDEAIKEALAWKNSFAERTGAALDIVTQFAFEAEPL
IAWDRRINADGNKLPIRIGLPGLATIKTLLGFSKAAGVGNSIRFLMKRAADVTKLMTVNA
PDKQVIDLARYVAEDANAGISGVHMYAIGGLKRSSAWSYALRDGLFDVTNQDQIKVAVDL
G
>A0A1F2PI92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacterium wieringae|TrEMBL
MKKMVISFEISPIQSIQKIQSQKKKIDQLCSFNPNYISCSISGIKDVSFERNLEMCKLLK
LDKRTVPMTHFAIGGKKKKELTDRLKTYVSIGIEHYFVIRGDSKYHSQRSDAFPNSFSFI
KTIKKLNPDIHVSVAGYPETHILADSVKTDIKHLKLKQEFGADKIITQICFDGCAIADWL
DLCQKNDIHVPVDISILPVTNKNSILQISFANGISIPKELSKIIGRYGDDPQDFKKAGID
YTIKQIDALKKLGINGFHFLGGNNTSTISEVLNMASLANNN
>F2QEV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis (strain Uo5)|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A318K2P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia tenerifensis|TrEMBL
MPFSVEFNPPRDAAAEARLWRAVRQFERMHPAFVSMTYGAGGSTRDRTVRVTGELAQETT
LLPVAHLTAVEHSLSELRSLVGSYADSGIRNILVLRGDPPGDPLGEWQQHPEGVAYAEEL
VRIVRDLGDFHVGVASFPQGHHRSPDLDSDTAFLAAKLRAGAEYSITQMFFDVEHYLRLR
DRIAKFDPIEGAKPIIPELMPITSLRTVARAEELCGRALPASVLERLNKAAGDTPEDNQA
AVREVGIEIATEMAQRLIDEGAPCLHFITLNFAKATTEVLTNLGYGVTAAPISA
>A0A6L7UHV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MNPPALNSSPSGGSWVKQPLAHLLQQTDSFVTCIELVTSRGIITERSGRRVLDLARGLAR
HPQVHALSITDNPGGNAMLSADTLGTDLIARGQEVIIHLSCKDWNRNALQSRGWKLASEG
FNNILALSGDCPTGGYAGQASGVFDIDSVGLLKMYSDMNAGLTEEGRGEATMAPTRFFLG
AVVTNFKRHEREVMPQYFKLALKVRSGAQFIINQIGYDSRKQDELLKAMSHYGLQVPVLA
NVYVLSRPAARFFNSGAIPGVVVTDELLSLVEKQAKSPDKGRAFFLELAAKQCAIARGLG
YRGVYLGGHLKLEHYARLLSNADSYA
>A0A7W0TL34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MPGTVRDQLAAGEPTFSFEFFPPKDEGSEAVLWRTLRELERLRPSFVSVTYGAGGTTREG
TVRVTERIATQTTMLPMAHLTAVNHSVAELRNVIGGFAAVGVRNILAIRGDPPGDPSATW
IKHPKGIEYADELVGIVRRAGDFCVGVAAFPYKHPRSADIHSDARYFVQKVQAGADFAIT
QMFFDAEDYLRLRDRVSVLGCDVPIIPGIMPVTSMGTIERAPKLSGAPFPPALAATFEPI
AQDKDAVRAQGVSQASALCQRLLDEGAPGIHFITLNRSTATREIWANLRQTAPTG
>A0A7V9E5K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MAADDLDGEVLASALAELTRGFSVEVTPREAPKVQHFGEVLAEGTRVYITFLANTPFEDT
LALARRAVDEGMRPVPHLAVRSIPSRRALTGMVAALADVGATEMLVIAGSVSKPAGEYEE
TMQVLASGVLPEHGITRIGVAGHPEGAPDISATELAAALAAKNAVAAEQGLDLYIVTQFS
FAPEPIVEWEREIRAAGNRLPIVIGLPGLTSPAKLLKFGLSCGIGPSLKVLRKQSGGVLK
LATSSVYHPDQTMLGLVRSRVSDPASLISGVHFFPFGSLERTAEWARQVSAGQFVVDTNN
TLRVTA
>A0A2V8HLF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPLPDFRTELDKRVLVCDGAMGTMLYAKGIFLNRSFDQLNLTQPDLVAEVHQAYVRAGAD
VLETNTFGANRIKLGAFGLADRVQTINVQGARIARHAAREQAYVAGAIGPLGIRIEPYGK
TGVDEAEEYFREQARALVEGGVDLFVLETFRDVNEIGAAIRAVRSVGDLPIVAQMTTEED
GNNLDGVAPETFVPELEALGADVVGLNCSVGPAAMLETIERMARIAHVKLSAQPNAGRPR
EIEGRNIYLCSPEYMASYARRFIANGVRFVGGCCGTTPDHIRHIKMAVRAIAPSAVTSVR
SRTGSGRTDAARTTPAVAPIARAEKSRMANALARGTFVVSVELIPPRGFHAETIVEQARQ
LKIHGVDLVNIPDGPRASARMSALSAAVLVQQQAGVETVLCFACRDRNLLGMQSDLIGAH
AMGVRNLLLVTGDPPKLGDYPDATAVYDVDSIGLTHVVARLNRAMDVGGEPLGQPTAFHI
GVAANPGAMNLEEELRRFAYKVEAGAEYAVTQPVFDVAELRAFLDRVRDHRIPVIAGVMP
LAGMRHAEFMANEVPGVRVPETVLDRMRRADAAGRAAEEGLAIAREIAAEVRPLVQGVHI
STAPKAIEAALGVVEAVGA
>A0A7X8YUN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSPSRLQSVLEAGKFAVTAEAGPPRGPDAEAVRRKARLLKGSVDACNVTDNQTSVVRMAS
MAACRILSEEGVEPVMQMVCRDRNRIAAQSDILGAAALGIPNLLCLTGDHQSFGDHPQAK
NVFDLDSIQLVKVAREMRDASLFAGGKALEGKLELFIGASANPFADPAKIQVPRLAKKVA
AGAEFIQTQCVFNIEKFKEWMNDVRERGLDTATHILAGITPARSAAMLEYMATHVAGMDV
PEAVIARVKGVPRDKQAGEGIRIAVETVRQLREIPGVRGVHIMAIEWEESVPEIVKEAGV
R
>A0A2V9ACX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIFDFNERLKDAILIADGAMGSMLHEAVGPQRCFDELNATEPEAVFRVHQAYIEAGAQI
IETNTFGANRFKMAPLGLGDEVQRLNSRGVKIAREARESAAREVLIAGSIGPLGLGVQAR
HPDDKEILDVFYEQALALEERGVDFYILETFSYIEEVLLAVDAIRSFSGLPIVAQLTYSE
EGTTHGDIRPSDAAVQLKNKNVQVIGANCTLGPQALLPILQELAAVDDIRISGMPNAGFP
KREGDRIVYPKSSPEYFALFAREAAALGVRILGGCCGTTPAHIHAMAEAVKLLRPAKSHP
ASPAVEAVTKPAPLSQREPESQFWKNLKAKKFTVCVEIDPPKGLSLDRIFEQVDRVMASQ
KVDAIDINSGAMARVGMDALVVAGALEARGVETVPHLTTRDQNIIGLQAGLLGAWTVGGV
RNVLAITGDPPSVGDYPETSGVYEVDSVGLVKVLNRLNQGTDWAGKTLGGATNFAIGVAL
NPVAYDLESEIVRFHAKVEAGAHFAMTQPLFDPEHWHMFLKKLGGKPAIPVLIGVWPLNS
YKQALRLNNEVPGIVIPEALLKSMEAAGAAARDCGFQVARQMLAWARTELAGAYLIPPFK
RYEEVLEIL
>A0A0D8BVD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus kaustophilus|TrEMBL
MGLLDELKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDDVPAINRAAVRLAKQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELEAVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIEVMAKALSDRTPVTEKTVKRRATSVS
VSADIPSAATPLPELARTRRSVIVELDPPKKLGIDEFLTGAKALHDAGIDALTLADNSLA
TPRISNAAVATIIKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVER
MEKKIQCGAHYFLTQPVYSEEKIVQMYEATKHLDTPIYIGIMPLVSARNAEFLHHEVPGI
TLSDEIRARMAACGGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRY
IHEKEAALKERKVVHG
>A0A8H9ZF49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. BW16M2|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYQAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFETDLANFVHKVKTGADSAITQYFFNADSYFY
FVERAQQLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2V9C6W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIHDFNQRLKDAILIADGAMGSMLHEVVGPQRCFDELNTTEPEAVFRVHQAYIEAGAQI
IETNTFAANRFKLAPLGLGDEVQRLNSRGVKIAREARESAAREVLIAGSIGPLGLGVQAR
HPDDKEILDVFYEQAMALEERGVDFYILETFSYIEEVLLAVDAIRSFSGLPIVAQLTYSE
EGTTHGDIRPSDAAAQLKNKNVQVIGANCTVGPQALLPILQELAAVDDIRISGMPNAGFP
KREGDRIVYPKSSPEYFALFAREAAALGARILGGCCGTTPAHIRAMAEAVKSLRPVKAHA
ASPVVEAVAKPAPVSQREPESQFWKKLKKKEFVVCVEIDPPKGLSLDRIFEQVDKVMASQ
KVDAIDINSGAMARVGMDALVVAGALEARGVETVPHLTTRDQNIIGLQAALLGAWTVGGV
RNVLAITGDPPSVGDYPETSGVYEVDSVGLVKVLSRLNQGTDWAGKTLGGATNFSIGVAL
NPMADDLDNEIARFHAKVEAGAHYAMTQPLFDPEHWHAFLKKLGGKPAIPVMIGVWPLNS
YKQALRLNNEVPGIVIPEPLLKSMEAAGASARDCGFQVARQMLAWARTELAGAYLIPPFK
RYEEILEIL
>A0A6L7K9Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRRSELAAFLRERPRVGDGALGTALYAGGIASRRSFEDLNRSDPDRVRAVHTAHLAAGAE
VISTNTFGANPWKLGRHGLASEVATINAAGAQVARSAVRPGSLVFGSVGPSGEVVGPFDE
EKAPEFAAGFREQIVALVESGVDAVLIETFTSLAEARLALSAAREVAPDIGVIVLMTFSE
QATTLFGVAAEQAAGTLERDGADAVGSNCGVGPDTTLAALERMRDAVSLPLVAQPNAGIP
ERTEGRFLYPSSPDYVAHYAKRYLRLGVSLIGGCCGTGAEHIGAVAGVVRAASAGARADR
VKAPARPATATPAEHAPAEIPAVPVPERSGLARCLAEGRFAVSVEMDPPRGAEPGKFLAR
VGDLADAGIRFVNVADGPRATARMSAIAFAALLERSGEVESILHYQCRDRNLIGIQSDLL
GAHALGIRNLLAVTGDPPKLGDYPHATPVFDVDSIGLVRILRGLNHGLDLAGNPLGAALP
FHIGVGANPAAADVEGEMGKFEKKVQAGAQYCLTQPVYETRLLERFVKDVRGYGIPILAG
VLPLVSSRNAEFLHNEVPGMSVPRSVRERLAAAPTRQRAREVGVSVARDMVAAARDLVAG
VYVMPPFNRFDLAIRSVTGLV
>A0A7D4PVH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hominis|TrEMBL
MTIDLSAPPVPISFEVYPPRSESGMVALHETIARLAAVGPRFISVTYGAGGSTGGRSLEL
LRHILHETHVTPLAHLTCVGSTYAAATALIREFLDAGITSFLALRGDPPAGVSEDEVFLG
DLESAAQLVQLIDRVQAERAPYSETAIPGVPDAVRVGRRPRADIAVAAFPNGHPRSRYPT
EHIDALLAKQAAGATMAITQLFFHADDYLSFVQRARAAGVGIPILPGIMPITSPSRLRRV
LELSGEQLPGELAVALEVETTAEGQRAVGIAHAAGLARDVLAGGAPGVHLYAFNNHDTVL
ATLGAAGLLSDPRPTAAQEAER
>A0A1Z8AEE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium 52_120_T64|TrEMBL
MTYETPQTTSLSFEFFPPHNAEAGARLWRSVERLAPLGPEYVSVTYGAGGTTRERTVSAI
KTIQDRARLNVAGHLTVVGASKAETLDVARGYAAQGVRRIVALRGDAPKGQDHFTAHPDG
FQNAAELVAGLKDAGDFEISVAAYPEKHPDSADMKADIENLKRKIDAGASSAITQFFFEN
DDFLRFRDAAADAGITAPIIPGILPVENFTKMLRFADMCQAKVPDWMHQAFRNAGDDTEI
LATAICAEQCDELQTEGVDHLHFYTLNNPDLVYNISRALGFEAVGVDLAASVA
>A0A3N5GB78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MEETAAPAAPVENQVSLGDREPAAFERACRSGRFVVTAELSPPDSVDPQDLLRRAVAFRG
LVDAVNVTDNAGGNCHMSSLAASALLAADGFTPVFQSACRDRNRIAMQADLLGAAALGVR
NLLCITGDGVGSGDHPQARPVFDLDAVSLLGIARGMRDEGTYASGRKLTSRPDLFLGATV
NPFAPTFEARIVNLEKKITAGAQFIQTQFCFDLKLFENFMVEVRAQGLDRRCHLVVGVGP
LPSVRTARWLNGNVPGVRIPGEVIGRLEQATDPKREGIKICIETVHALREIAGVAGVHLM
GHRNENILAEIIVESGLRSRVGMDAEASRSVVG
>A0A2K9DWR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hominis|TrEMBL
MSLAAGTAPRVAGCPKSMAYGPCGGVNPDGTCEVDPTPCVFLRRDLPVRWDGNGDAPVDR
DPVDAVTTAAGREVAEIAQRRPLVFTGFPVRALRSDAVRPTADALSGSVDAVLSGDAGRS
RVQFPPSYRAALIAATGLRLWMGFNARDRNRTALERELLSLRALGVAGVHCVTGDHTQTG
DRADARPVFDLESTTMLPRARALGLLTSFAESPAAPPVAERGARVAQKQGAGGRLCLTQY
AGDAEEVADFVAQCRAAGATAPVLPGVPLVIDRDGAGLLASFHAAKLPRGFIDRLFAARD
VRAEGIRLAIEYGRALLDTGLVGGVVIAGGARLGEEVSYAADLATVARELGGGT
>A0A5M3VQV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acrocarpospora corrugata|TrEMBL
MSGEGGLRAALASDRVVVTAEIGPPRDADPEVITRKAAALRGWVDAANVTDNQGANVRMS
SLAGSVLVRRAGVDAVMQLTCRDRNRIALQSDLIGAAALGVRNVLLLTGDHPALGDHPDA
KPVFDLDGVQLVWTARTLRDEGKLLSGKALATRPSWLIGSVENPFAPPAALRARRLAKKV
AAGAEFVQTQYVFDVDAFAQWVRRLREEGVTERCAVIAGVGPIRSLRMLSFLTGEVPGVH
VPPELERRLRGVPAHRVEAEGLAACVETIQTLVEIPGVRGVHLMVFGHDDEVPDIVRRAG
ISRKGDSDVD
>A0A2V9YLB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
DCINIPDSPRASARMSNQALSLLIQQQVGVETIMHYTCRDRNVLSIQSDLLGAAAVGLRN
ILCVTGDPPKLGNYPDATAVFDVDAIGLVNIVHNLNRGLDIGGNVIGGKSGTGFVIAVGA
NPGVPNLDEEIRRFEYKVEAGAEVAITQPVFDVALLENFLKRIEHCRIPIVAGIWPLVSL
RNAEFMKNELRVSVPDAVVQRMAAAPNPEAARHEGISLAREMLQSVRGLVQGAQISAPQG
RYSSAVDVLEALGSARKSTVQVGS
>A0A2S0HXA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pukyongia salina|TrEMBL
MKVTEHIANGKGKTQFSFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYVYKE
MENGLLQKKVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKTETYFTPEKEGHRYANELVQQIDALNKGEYLDEEIMNQAQTDFCIGVAGY
PEKHMEAPNMESDLHFLKKKLKNGAEYIVTQMFFDNNKYFEFVEKCRSAGITAPIIPGLK
PISTKKQLNLIPQRFNADLPEALIKEVLKCETNEQVKEVGIEWCVEQSKELIKEKVPFLH
YYSMGKSDNIKAIARQLF
>W5XPY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium casei LMG S-19264|TrEMBL
MSASAPLDYLELDHAGNPRAAGVGKAPGRTSLSFEVIPPRHDADSAKTENLLQVLGSYNP
DYIAVTSSKRSGWLEGTAKFIAQISSTTSMRPLAHLACTAGDRQQLISWINVLVDAGVRG
FLALRGDLEPGQDKLPEGYLQHADELVRLIRQLEGEQAARFAAGRLAVGVACYPNGHAES
ANADEDFDVILSKQRSGADLAITQLFFDAEDYLKFAQRARLAGTRIPLIPGIMPITSLKR
VQRMGELSGLEVPQRLIEKLSLARSPDEEYAIGMAHTVELARAVLAGGAGCLHIYTHNNA
SITQELLSSIGITPDVKKQP
>A0A1Q9UUP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serinicoccus sp. CNJ-927|TrEMBL
MSSRISVELVPRSAESVRSEMAQVADRLRGVDTVNIPDLLKFDLRSWQATEVARDAARRA
DGTAYRTIPHIRAADVDPDAPLPMADEARRTGELLVVSGDDADYFHSATYPVDAVDVIRR
VRAELPEVTVYAGLDPYRQAMTTEMRYLDRKLAAGANGIFTQPFFDTHLMAAWASVLPEG
IDVWWGATSVTTSGAMGYWRRRNRVVFPAGFDSSMPWQRDFARRVVDFARERGHHAYLMP
VRAPLLDYLGGVLDG
>A0A2V9RN53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIRDLLKHDRPCFSFEFFPPRDEAGFQNLFETVSLLKQLNPTFVSVTYGAGGSTRRKTI
DLVTRIKHSLGLESMAHLTCAAASRQEVQQVLEELVANRMENVLALRGDPPKGQSEFVPD
PNGFRYANELVQFIRSHYDLCIGAASYPEKHPECTSLEQDLINLKRKVDAGADFLITQLF
FDNCHFFNFVECARKIGINLPIIPGIMPILSVPQIKRFTEMCGAKIPDELLRRIESVQSD
PAAVERCGVEHATAQCHELLEQKAPGIHFYTLNRSKATWEIFKNLTSRWPQSHLR
>A0A2N0B1X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira levettii|TrEMBL
MHISEILGKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEETGLTIVSHLTCVGSTKEEIGEILKRYQKSGIHNIMALRGDPPKGQNEFQKT
ENGFEYAGELVGFIKANYPNMGIGVAGFPEGHPSTPNRLKEIEYLKWKVDQGADYICTQL
FFNNDSFYDFVERCEIAGIKVPIIAGIMPITSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDAYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRKIYESLGIRNFDRIV
>A0A6G8CDC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp. HDW8|TrEMBL
MKVTDHLIKADGKTLFSFEVLPPRKGENIQNLFSNIEPLMEFKPPFIDVTYHREEYVYRK
QPNGFLERKTVRKRPGTVGICAAIKNRFDVDTVPHLTCGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSESHFIPEPDGHAYASDLIEQVACMNQGRYLDEEQEDTFPTNFCIGTAGY
PEKHFEAPNYGSDIRFLKQKMDRGAEYIVTQMFFDNEQFFNFEKRCRAAGITAPIIPGLK
PMTTKSQLTMLPRTFFLNIPEELAEAISQCRDNEDARRIGIEWCINQSRELMAHGVPCLH
YYSMGKSESIRRVAKELF
>A0A7W7W1E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lipingzhangella halophila|TrEMBL
MNLGQTLQNGILVCDGAMGTMLHAAGNSLDQALPALNLTNAALVGTIHNSYVDAGVDVIQ
TNTFGASRLRLSAYGYGDQVEEINRAGVRLAREAAQAGRSVLVAGSVAPAVNVHQRRRTS
AAQRRDALREQATALAGAGVDLVLLETFGYLDELVEAVEIATEQAAVPVVAQATFGSDTR
TLSGHTPRDVVTALAGAPIEALGFNCTLGPQGSLAVLRALREHTDRPLTVQPNAGLPRRV
APARFEYDIDSEYFLRYVRELLDSGARLVGGCCGTTPTQLAAIVQAAEEYRRRSGPELVA
TPRASARPSTAADGPAPITGPDEFMVELAPSPAGGVEESLDIARQLRDAGIGQVSVVGSR
NARAQVNPVNLALHLHQRLGIETLASVTTWDRTIMALQADLLGAHTLGLRRIICETGNPP
LLGDYPHVDGIWDVDSYGLIELLAGLNNGEDYSGFQLPAKTEFEIGARINPGSREPTREA
ARATWKIDAGARFLVTRPVFDPADLERLLELISTDNVSVLAAVQPLTSFAEAELLAHEVP
DVRIPRRTLDALYNAGDHAHGVGLELTLDLVSRIRGLVNGVVLAPTANPVATVRAIVAGS
>A0A7Y4LBC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelistega europaea|TrEMBL
MSRQNFFSLEFFPPRDVEAAERLQKTTQELLVINPDFISVTFGAGGSTQEGTLETVRMLK
AQGIKAVPHLSCIGNKADRILGILEQFKQMGVDRIVALRGDLPSGMGLVDNGLRYASDLV
SLIRQHHGDHFHIEVAAYPEMHPQADSPSADLDHFITKVKAGADSAITQYFYNADAYFDF
VNRLQAKGINIPVIAGIMPITNYSQLSRFSQMCGAEIPRWIRLRLAEFGDDRASIRSFGI
EVVSQLCQQLIDNGAPGIHFYTLNQSAATLAIWNNLNNA
>A0A2S0L199|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Victivallales bacterium CCUG 44730|TrEMBL
MLYFIYLITKKQPNWNDTMNCLQRKLAESLVIFDGAIGTEIYRRNFFVNASFEQLSVTNP
DVILDIHRQYLDAGAEVLTTNTFNANARRLGKFGLADQTATINRASAELARQAVREAGLE
GSVLVAGSVGPIGEPESAADTRSRDSILVEQLEALAPVVDFIIFESLRTTIDLAAALEAV
KAFPELVYVLSFAVDRHAENHSGDGISEFGRLISTFPGQRPTAIGLNCGGGPESTLGELE
ILVKRTKLPVIVQPNAGQPRGVDGRMIYMTSAEYFSTYAKRYAMLGAAAIGGCCGITPAH
IRELARTIKPLMRAEKQELPKVEIVECDLKEPVPLAEKSSLGAKLAAGKFVTSVEITPPR
GFDLASTVAGARKCKEAGIDAVNLPDGPRASARISPFAAAVAIQQQVGIETVLHCCCRDK
SVIGLQADLLGCAGMGINNILFITGDPPKLGDYPFSSGVFDVDSIGLVKIQSRMNRGIDL
GGKSISAPTRAVIGVGADPSAIDLEREYRRTCEKVEAGAEFIITQPVFAIETLFAFLDRI
AHLKTPLIAGIWPLVSYRNAEFMKTEVPGVVVPDAVMKRMAAAGTKEEQREAGLEIARES
IAAIRDRVQGIQVSAPFGNVDLALRVLK
>A0A7V7WBH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella anthropi|TrEMBL
MGFYGLSRRPDIGQTTRVSFEFFPPKSEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDVKPAAHLTCVDATREEVDRVVCEFAALGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPSWLAERFE
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTEAAL
EVA
>A0A7L6WL25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFKYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHEATHSLFKHHSQVSAL
>A0A2N1UKC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira bacterium HGW-Nitrospira-1|TrEMBL
MKSGSNLEKVISSGYPAVTAELGPPMSADGHEVRKKAQLLKGFCDAANVTDCQTAVVRIS
SIAAAAIALQEGLEPVMQMTCRDRNRIAMQADLLGGAALGLKNCLCIAGDHQSFSAAGRL
KGHPGAKNVYDVDTCQLVGILKKMRDEGKQEGGDPLEAAPKFFIGASWTPMADPIDFRPI
NLMKKVNAGADFIQTQGIYDIAGFRAQMARIVNMGLHERTAILGGIIVPKSAMMLKYMDS
SVAGVSVPKSLIDRMNKAKESAGDDKKKARELQEQEGVRIAIELIQQVLETPGIKGVHIQ
AIEWESAIEGIVKAAGLYPRPTFFET
>A0A7R9UV70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diacronema lutheri|TrEMBL
VRAALDAARAAGIVNVLALRGDVPAAVEAATDGVRAAPGSGALTFPHAVDLVRFIRAHYG
DAFCVGVAGYPEGHVDGESYEADLAHLAEKVAAGGEYILTQHFFNVRRFSQFLDDCKRIG
INVPVIPGVMPIHNYESFARIVRFCRTDVPASISAALEPIRNDDEAVKRYGTVLASEMAS
ALFELGCGGVHFYTLNLEQIVTQVLLMHGFARQPARRLVPWQHARTADSALPPPPAARGG
GGGGAPQGEP
>A0A7T4PRC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mammaliicoccus sciuri|TrEMBL
MSLKEALKNQILVADGAIGTILYSEGLDTCPESYNLTHPNKIEQIHRSYIEAGADIIQTN
TYGANFEKLQDFNLEHRVKEIHREAVQIAKRASNDHTFILGTVGGFRNIKKSNLSIEAIQ
YHTEIQIETLVNEGVDGILFETYYDLEELLAVLKDTKARYDIPIIAQLTASNTNYLRNGT
PIPDALETLVKAGADVVGLNCHHGPYHMIKTFKHIDLPDHAYLSCYPNASLLDLEDNDLK
YNNNSDYFSDAAKELVNQGVRLIGGCCGTTPEHIKKIKNVVKDLKPIKHKNVIPIETKQY
KKQNKEEPSIKELVQQRPTVIVELDTPKHLDTNKFFDGIQALEDAGVDAVTLADNSLASV
RISNIAAASIIKQKYKIRPLVHLACRDRNLIGLQSHLMGLSLLGINDILTITGDPSKVGN
FPGATSVFDVNSSGLAEIITQFNQGINADGDTLRSNTNFSVAGAFNPNVRRLEPAVKRLE
KKIESGMEYFITQPIYEPERVKEIYEATKHIDAPIFIGIMPITNYNNALFLHNEVPGIKL
SDTVLNAFEKVKDDRDATRELSINLSKQLIDAVHQYFNGLYLVTPFLKYDLTVELANYSK
LKTGTQTKEAIL
>A0A0F4XQL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas kilonensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGASSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A0S7Z2B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium SG8_30|TrEMBL
MPQKPGPTGREPVQVSFEFFPPNDEAMERTLWSSVERLAPLAPRFVSVTYGADGSTRERT
HNIVSRIRAETRLTAAPHLTCVGASRGEVLDIARRYWDQGVRQIVALRGDPPAGSSRYVP
HPEGFDYAVDLVAGLRTVGDFEISVAAYPEVHPEAPDATFDIDNLKRKQDAGASRAITQF
FFDTGVFLRFRDACARAGVNMGIVPGILPITRFPQLTRFAARCGASVPGWLVERFEGLDE
DADTRKLIAAAVAIEQVARLRHEGVSEFHFYTLNRAELTYAICHALGVRPQARAA
>A0A0F4RIZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loktanella sp. S4079|TrEMBL
MSTPSISFEFFPPKSLEGSFRLWDCVNVLAPLDPTFVSVTYGAGGTTRKLTHEAVGTIHR
TSGLNVAAHLTCVDATKAETLEIAEGYAQEGVREIVALRGDAPKGSDGFKPHAEGFESSV
DLISALADTGKFKIHVGAYPEKHPEAVDQAADIAFLKRKIDAGATSAITQFFFEADTFFR
FRDACVKAGIDAPIIPGILPIENWSGAQRFAKMCGTSIPQIVTDAFEHATREGTTDLLAT
ALATELCDDLLQGGVDHLHFYTLNRPELTRDVCHALGVTPKGRLQNVA
>A0A3D8P7L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ammonifex thiophilus|TrEMBL
MKSGSRLERLLSQGEFVVTAEIGPPKHASAEPLIRKARLLKGYVDAANVTDCQTAVVRMA
SIPAAVHLLREGVEPVIQMTCRDRNRIAIQADLLGAYSLGIRNLLCLTGDHPAVGDHPEA
KGVFDLDAVQLLDMVRRLRDEKVFQSGVPLKGPEPRFFLGAAENPCGAPVELRIMRLAKK
VEAGADFIQTQCVFDLECFSRWMESVREEGLDRRVYILAGVTPLKSARMAQYMHENVPGI
SIPEEIRERMAKASDSQEEGIAIAVETIQALKRIPGVAGVHIMAIAWEEVVPEIVRRAGL
FPRPQLPEETDR
>A0A0A0BFL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga thiooxydans|TrEMBL
MGWFLSAHFFNKSKKNMSNNLTISCEFFPPKTEKGIANLRRVREELRPLAPEFYSVTFGA
GGSTQDNTLEAVIDIQKQQPETDIDAAPHLSCVGSNADRLRTILNTYRDNNIRRVVALRG
DLPSGMRDPGDFRYANELVEFIRNETGDFFNIEVAAYPEVHPQAPTAELDLENFKRKVDA
GADSAITQYFYNIDAYRFFLDRCEKLGIDIPIIPGIMPINNFAQLSRFSAGCGAEIPRWL
RKRLEEFYDDTESMQAFTLDFLTEFTQQLIDIGVPGLHFYSMNKTQPTLTVCERLGLVKT
>A0A2N5I543|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. M6-12|TrEMBL
MCWCRRSLCQGACTFHRGGLKVDFRHELQKRILIGEGAMGTLLYINGIDQCYEELNILEP
ERIENIHATYVEAGADILQSNTYGANYIKLKRYGLEDQVSKINRKGIEIARKAAGKDAFV
FGTIGASRSFRKSDLNLEEIKRSFREQLYSLLMAQPDGIILETYYDLEEIETVLEIARNE
TQLPIIANVSLHEIGYLQNGVHLSEALGRLEAIGADVVGVNCRLGPYHMIRALEEVPLPA
QAHLAVYPNASLPDFEDGRLVYAAVPEYFETSALELRKQGARVIGGCCGTTPMHIEAIKR
AIGSLKPVMEKTVKRRKIEINDTGRKDTTVAIAEKAKRERTILIELDPPKKLGIEDFMAG
VDALYEAGADSITLADNSLATPRISNGALGMLIKNNTGHNPLIHLTCRDRNLIGLQSHLM
GLDTVGLNEILVVTGDPSKIGDFPGATSVYDLSSFDLISLIKQFNDGLSYSGQPLGQKTN
FRIAAAFNPNVRYLAKAVERMEKKIKCGAQSFLTQPIYSESQIEEVYQATRHLETPIFLG
IMPLTSSRNAEYLHNEVPGIKLSDPVRKAMAAAANDPVKARAEGMAIAKSLAEAAADRFN
GLYFITPFLRYDMTAELTKHIRTIDSKRLVEVAAYE
>A0A4Y6T707|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. NIBRBAC000502774|TrEMBL
MRSETARQNGEIRGDIRLSFEFFPPKNPEMENQLWETVAELKKWDPDFVSVTYGAGGSTK
APTLDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIGT
DYRPHPQGYENAAALVKGLRDISDFEVSVSAYPEKHPESASDAVDIDMLKRKADNGATRA
LTQFFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPNFLDERFA
GYDDDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A1I3NDA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronobacterium gregoryi|TrEMBL
MSSEIRTGEVADGIVTLLEEPRFELMPFDSMDDQLEHLPDGAEIAITTSPTLGLEATIDW
TERATDRGFEVVPHVAARYVRDEDHLAEIAGRLTDAGVTDVFVPGGDREEPIGEFTSAYD
LLSTLEDLAYEFEGIGITGYPEGHDFLDDEVLAEAMAKKEPYATYIVTQLCYDPQTILEW
IEEIRGRGVDLPVEVGIPGVMKYQRLLQISRKVGVGDSIRFLQKTSGVLGFLKELVGSRG
TYVPDELVAGLAPYATDSYYDVCGVHVYAFNQVPDLESWRSETLTQYG
>A0A6M5ZKW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii|TrEMBL
MVLKNEARDRNIRVSFEFFPPKSEEMEGQLWHTVSQLQDWDPDFVSVTYGAGGTTKAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESLDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFEGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRRQTRTAGAAA
>A0A6A6NKM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hevea brasiliensis|TrEMBL
MATTLALLSLVIQVLKAILGFLLCPILLHYPQKIISLCSSVIFRSEAHPDMIRSDGVATP
ENYQKDLEYLKRKVDAGADLIITQLFYDTDIFPELVNDCRQIGINCPIVPGIMPINNYKG
FLRMTGFCKTKDLSLDEGRTLSWEQYPHDRWEDSCNPSYRALADYQFMRARARDKKLHDE
WATPLNSIEDILEKFKKHCLGKLKSSPWSELDGLQPETKIINEQLGKINLKGFLTINSQP
AVNGERSDSPSVGAERLLFGQLGR
>A0A7U5CUT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas hengshuiensis|TrEMBL
MPGTNKTCGLIDRWSVEITAKDADRLEEAAALVPPGTKVPVTFLPGETFEARVATARRVR
ELGFVPIPHISARRLHSEAELRDFLAALRREVGNDHCFVVAGDPPEPLGPYPDALSLIRS
GMLAEHGIKRVGISGYPEGHADIGNDKIWQATRDKRDLLLQGGHDFAIVTQFGFNAAPML
AWVEQVRDAGIDATIRLGIPGPASVKRLLGFAARCGVAASASVMAKYGLSVTRLLSNAGP
DRLVEELAERFDPARHGDVLLHLYPFGGLRATAEWVRDFQARHGCAIGG
>A0A366SPH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus cecorum|TrEMBL
MSGACYPEMHPDSNNRVEDILNLKRKVESGCQQLITQLFFDNDTFYRFQESCALSGIDVP
ILAGIMPIINRKQAIRLIQTCQTKVPRKFMAILEKYEYQPESLKEAGLAYALDQIVALVT
QDAEGIHPYTMNQADTARYIYQATTAIFQNLSHAS
>A0A4Z0PBH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter fodinae|TrEMBL
MKVTEHLTRANGKTLFSFEVLPPKKGENIQNLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGFLEKKTVRKRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFKPDPDGHAYAADLIGQVANLNKGEYLDEEQDDTWATDFCIGTAGY
PEKHFESPNYGADLRYLKHKVDRGADYIVTQMFFDNEQFFNFEKRCREAGITVPIIPGLK
PLTTKSQLTMLPRSFYLNIPEALADAVHHAPDNAAAREIGIEWCINQSKELMAHGVPVLH
YYSMGKSESIRRVAAALF
>A0A413BM63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHAHATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDDDAKQLGIEWTTTQVQDLFEHGYNNVH
FFTVSAVDSVKQIAKILF
>A0A3E1B5T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii|TrEMBL
MTIAPQSESREKAPLADLLSHYSIEVTSRDLSSLQSMTATLRPGSEVFIAHLPKEDIGLL
VRTAAGLRDAGFVPVPHIVARNIRNRPELDTMLARLSEEAGVRHALVLGGDRDDVAGAFG
SALDLIETGLFQTYGIGRIAIACYPEGHPRIESGVLDTALTAKVDAAARAGLDVLLVSQF
LFDPKPLVSFARRLRERGVTAPLRVGIAGPASRKKLLKYALRCGVGASLRALRERGEIAR
NVLSGETPEELLIDIAAAQAAEPDLGISGVHFFTFGDPAQSIRWAEQQAPD
>A0A024SKT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypocrea jecorina (strain ATCC 56765 / BCRC 32924 / NRRL 11460 / Rut C-30)|TrEMBL
MHIRDLVADTEKSGAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLEKVNDALQKAYKAGCTNILALRGDPPRDQTS
WKAADGNFQYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGAGF
IVTQMFYDADNFIRWVGRVRERGITVPILPGIMPIATYASFLRRAKHMQCRIPPDWMAKL
EPVKNDDVAVREIGKTLVADLCRKLLANGIHHLHFYTMNLAQATRMVLDELNWTPSPERP
LKQPLPWKQSKGFGRRDEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKKWGEPKSVQDIATTFVQYLEKKIETLPWSESALSAEADPIKDDLVA
LNKRGLLTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLMPPYLLEEMIRRLDDFP
NLTYYAVTKNGELKSNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGVDW
AHCFDAGTPSRALIEDIMNNWYLVNIVNNDFRENNTIFALLEGLEVKDLAVPASGTTTSA
SGTA
>A0A6P8MGT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bombus bifarius|TrEMBL
MKKFVSKDKVHDPCIDDECDNIADHFRSVDTKREMIDLRKKLQDIIKTDAIFCSFEMMPV
ISKDLLQSFFTEMNKYHPLFYALTWHKNDMKDYLSLDIFNILPNNTLLHLIAKDLTSTDV
KIILKEALEHGIRNIFVLRGDSTKSNSEFSHAIDLVRFIRNQFGNIFCICIAGYPEMHPE
SSSKEMDLIYLKEKVDAGANFIITQIVFEASIFIKFVSDCKNIGINIPIIPGIFPILNYT
CLQKMARICNIKIPKIILNTLECIKDNDEEVHNYAVEIATNIIKKIIASKTACGFHFFTL
NKPSLSLEICDKLNIFH
>A0A2R9SWC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus vortex V453|TrEMBL
MKPDLRQAWENQVLVGDGAMGTYLYQKGFPVGISYEELNLTSPEVIGNVHRQYVEAGAQV
IETNTFSANYDKLSKYGLETRVEEINRAGVRIAREAAGNHGYVVGAVGSIRAGKRNNIST
SELKRYFEEQLKVLISEGVDGILLETFYDVDEMQLALAQARMLSDIPVICQFAVEDIART
LDGFTMPDAYRILSQEGADIIGFNCRTGPNGIMRALETLNGVMNLPASVYPNAGIADYVD
GEYRYGASPEYFGKTALEFADRGARIIGGCCGTTPEHISEISLALSGYVPSPLPVVEEAE
VNRIVIHESAQEQFYERSGEPTIVDIVKERHTVIVELDPPRDLDITKFMKGAEALKKAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVVGAAFNP
NVRHLDKAVARLEKKIASGADYVMTQPVYDPELMVRLREATAHLEIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAMGVKIGKELLDVATEHFNGIYLMTPFMFY
EMSVQLMEYVWEKSGRRLTPLFH
>A0A7K0BMX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura macrotermitis|TrEMBL
MRHARAERTPTIRELLARGGRSFSFEFLPPKSEQGVRNLWRAVRELESLQPTFVSVTYGA
GGGTRDTTVDIVERIATETTLTPVAHFTAVNHSQAELRNLIGRFASVGVRNILALRGDPP
GDPMGEWVKHPDGIEYADELVRMIRSYGDFCVGVAAFPYKHPRSRTIEDDTRHFVAKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDIPIIPGIMPVTRLSTIERSEQLSGAPFPDEV
RKRFEAVADDPEAVRRLGVQHAAEVCQELLDQDAPGIHFITFNKSTATREVYGLLDGDRY
GASGSVPPMTA
>A0A1H9WY28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tranquillimonas rosea|TrEMBL
MTGTTPDQPISISFELFPPKTDKGMQNLGHTVDKLTQAGPEYFSVTYGAGGTTRDRTARV
VEMVANRSGIPVAHHLTCVGASRDEVDAQARGLWEAGIRKIVALRGDLPEGETLAEDGYH
DAAELTAGLRKIADFDISVAAYPEVHPEAENAETDIEHLKRKIDAGANKAITQFAFDTDT
VLRFVERARAAGIEAPIVPGIMPVANFASLKRFSAGCGASIPDWMEEMFAGLDDTPDLRS
MVATSVAVEQCRRLVAGGIREFHIYTLNKPEVSLAICRSLGLPVEIRADHAA
>A0A6N4B0Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio vulnificus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSTPQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAQTGLVAAPHLTCIDASREELINIANDYWANGIKNIVALRGD
IPPGGGVPDMYASDLVTLLKSLHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASHFAAQNNVKVPGWMAKQFE
GLEDDPVTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKKA
>A0A5M9ZT82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium tissieri|TrEMBL
MHKPIFSLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTQSDRTATARIAHTIR
AEYGIPTVAHLTALYADHEVVDRALDMFDEAGVTAVLALRGDELPDHETVGVFPHASDLV
AYIRERRPELKIFGACYPEGHYQAESLDQDIENLKIKVDAGASHLISQLFYDNEDFYRFL
DKARAAGIEVPIEAGIMPVRGAKSVRRMAERNASRIPKGLETILDRWEGNRDALHAAGIA
YASQQINDLVAHGVDGIHLYSMNHPGTTRRIWNNVKPLFQEV
>A0A4S4FIS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naasia lichenicola|TrEMBL
MGYEVLPFKATEDNVVKFVPKSVRLTVTASPPKGIEATIALAEKFAGHGYSVAPHLSAKM
IRDKVQLGEFVQRLKAVGIDSVFVVGGDAEEPAGEYTDALSLLKSLDSIGHEFTSIGIGG
YPEGHHFIPQDGLDAALKEKAQLATYIATQICYDAPAIISWARRIKSEGVDLPIRVGMPG
AVSREKLLRISLASGVGDSLKFLQKQKGMFWRFFVPGGYSPNKLIRGLKPAIGAADNNLQ
DFHIFTFNELEGTEAWRKQMLQRYPS
>A0A5N5ZMD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kordia sp. TARA_039_SRF|TrEMBL
MKVTEHIAQSDGKTLFSFEILPPLKGQDIKSIFDNIDPLMEYKPPFIDVTYHREEYTFKE
LDNGLLKKQVVKKRPGTVGICAAIQNKYSVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKAEKEGHRYASELVSQIQDLNNGKYLDEELQNSSATDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKAGAEYIVTQMFFDNQKYFDFVEKCRKEGITVPIIPGLK
PIATRKQLNLIPHRFKVDLPDDLIMEVVRCKDNKEVRKVGIEWCIQQSKELVAAGVPILH
YYSMGRSSNIEAIAKEIF
>A0A5N5SQA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armadillidium nasatum|TrEMBL
MVKEIEEAVPNSTEDTLSILKGFIESRSRESISESSSADSCLDCHIPKPDLIWGFPNLKE
KIVSRIESGDKFFSLEFFPPRTKGGAVNLLARFDRMRAGDPLFCDVTWHPAGNPGGDTET
SSMTIASAALNYCGLETMLAHDLLNHLKRAKDIGIRNILALRGDLPCDVEDWTPPEDGFR
YSTDLVKFIRQEFGNYFVICVAGYPNGHPEAESYEEDIKHLKEKVDAGADFIITQLFFKA
ETFINFVKDCRKAGIEVPIIPGVMPIQSYDSLRNIVKEVATTTILKQLGLWSCSPKRPFP
WKMAANHKRCSEEVRPIFWASRPKAYVYRTQHWDEFPNGRWGSSESPAFGELKDYYLFYL
KSKSSKDELLAMWGETLESEQDVWKIFACYLTGQPNPSGKKVTMVPWNDNELSPETSYLK
EKIGIFSIQKVSLPLTHNLTVSEDFSNCHKHRPLAVTWGVFPGIEIIQPTDEAFALWIEQ
WGKLYPEESHSRRVIENITENYYLVNLVDNDFPKESCLWDVLEAVFTWRNLNEDEQE
>A0A0Q6KA22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. Leaf344|TrEMBL
MMNAFRPSRHGSRSPNVSFEFFPPKTAEMETALWESVRRLEPLGPAFVSVTYGAGGSTRE
RTHATVKRMVEETALKPAAHLTCVSASCDEVDEVIRGYWSAGVRHIVALRGDPAGGLGTL
YEPHPQGYHQTSDLVAGIRRVGDFEVTVSAYPEKHPEAASLDADIDALQKKVDAGATRAI
TQFFFDNDVYFRYLDKVRARGIDIPILPGIVPVQNFKQTANFARKTGASVPDWLAERFDG
LEEDAATRRLVAAAVCAEQVLDLIDRGVTDLHFYTMNKADLVYAICHLVGLKPEKPAAQA
AVAA
>A0A0F8B9D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceratocystis fimbriata f. sp. platani|TrEMBL
MHISDKIANAKRAGEPSFSFEYFPPKTAQGVQNLYDRIERMNELGPQFIDITWGAGGRIA
ELTCDMVQQAQTIYGIETCMHLTCTDMGNAKIDDALSGAYKAGCSNILALRGDPPREKEK
WEPTDDQFHYAKDLVSYIRQKYGNHFCIGVAGYPEGCDDNKDEDSLLDHLKQKVDAGASF
IVTQMFYDVDNFLRWVRRVREVGITVPILPGIMPIATYASFLRRAKHMNCTIPADWLDVI
EPVKNDDVAVRERGRKLVTDMCHKILASGLIHHLHFYTMNLAQSTRMIIEELNWLPSAER
PIKQALPWKQSLGLGRRDEDVRPIFWRNRNKSYILRTQDWDEFPNGRWGDSRSPAFGELD
AYGIGLAGTSEQNRAKYGTPESVRDIAELFVRYLKKDLESLPWSESALTGETSIISDKLI
DLNSRGLITINSQPAVSGVKSSDPVHGWGPKGGYVYQKAYLELLVHPDVYPELIKRIESN
PDMTYYGVTKTGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGED
WARCYEAGSPSRQLIENIINNWHLINIVNNDFHQNDSIFALFSGLVVPGVNDIVPSSAPH
SPTLAQDAGSVKGPTEIAVNGTQ
>A0A1E9Z6H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC078H08|TrEMBL
MTTVHPALSFELFPPRSHASCESLLRTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDYL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDVQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMSVPADLAYALETATSSAE
LHRIGVEYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQSLSELEY
V
>A0A0E2N3M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSHC414A00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A388PC97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Planktophila sp|TrEMBL
MSNDQRATSFSLEFFPPKDLAGEERLWQVLAQLQPLKPDFVSVTYGAGGSTRDRTIRVTT
EITDRTQIPTVAHLTCVGSTKSELVEVLNQYKTSGIKSILALRGDPQGGPTSQWQSIPTG
LDHADELVELAMQIGGFNIGVAAFPDGHPASNFDLEKDIDVLLRKEQLGASFATTQFFFE
FEKWQGIVDRLAKRGSNLPIIAGLLPITNLKQLNRMVELSGVKIPNHISKRFESAGDDPS
EIKKIGIDIATELGSKLLAAKVPGLHFYTMNTAESTIVIAKNLGLVK
>U7L169|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. KPL1855|TrEMBL
MSPRFSASAPLDSMSEEELMVPERLALSFEVIPPRHDADEAKIDRLLQTLESYHPDYIAV
TSSKRSGWLEGTTAFIERISRTTSMRPLAHLACTAGSRTELIGWTNRLVDAGVRGLLALR
GDLPEEGLPEHYPQHADELISLIRQLEKQQAARFAAGRLAVGVACYPSGHVESKNEDEDF
DVLLKKQRLGADFAITQLFFDAQDYLRFTKKAQLAGVHIPLIPGIMPMTSLRRVERMGEL
SGLAVPERVRSALAAATTPEEEYETGMELTAELARDIVAGGASGLHIYTHNNPDNTHDLL
TRIGVDNDQR
>A0A4Q4MPD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria tenuissima|TrEMBL
MERITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCIGVAAYPEGHSDQSHPQHQDPQFDL
PSLIEKTKAGADFIMTQLFYDVEAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTTLSHAKLPSDMLARLDAVKSDDELVKQEGVKIMDEMVEHIKARPDTCRRGFHFYTLNL
EKAVSHIVEDTHLIPSTIDDNDDVIVETTPAINLEPPPNGFVPHRRRSSAVNSGPRNRVI
ISHSSAAKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKDDISKLFRRHIEGDLEAIPWSEQSLSP
ETLTISKQLLALNAKGWWTVASQPAVNGVKSTDPVFGWGPRNGYVFQKPFVEFFIPASEF
AALKPKLDAHEQVTYFAGNAAGEFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIFQEWQRIYPPRSASSTLLGALRRDYWLVNVIWGDFVQGEGLWEFLEQ
>A0A7S0A5S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrodinium bahamense|TrEMBL
MAATYADDAKIADLVAKASPGWFSFEYFPPKTEEGVQKLRNRIVRMKALKPLFTDFTWGA
GGSTSELTLQLTSAAKNEFGCVANMHLTCTNQKSEMCGEALDACKAVGVRNIVALRGDPP
RGHEKWTAIEGGFTCALDLVKYMREKYGDYFSISVAGYPEGHPDNIEAVEGGVAALTESE
KRRYRVAKDEHGAEVVSVCRDANFKKEMEYLKEKVDAGAQFVITQMFLDSQVFLDFVKTC
KEYGINVPIVPGIMCLNNFGGFQRMTNLCKTRLPQGLLERAEAANTSDDAFKAFGIEYGT
EMCKALLDGGAVGLHFYTLNLERVVVGTLKGLKLITEEQAAACEGGDKDAKFMVSAQGIT
TGTSLPAGKRLPGNRPLSEADPEMAKLVQEEKARQMRSIELIASENFTSRAVMECLGSAL
TNKYSEGQPGSRYYGG
>A0A846QRY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saonia flava|TrEMBL
MKVTDHIEKAKGETLFSFEIVPPVKGKNIQSLYDNIDPLMEFNPPFIDVTTSREEYIYKE
KDGLLDKKMTRLRPGTVGICASLQHKYGVDTVPHVLCGGFTKEETEYMLVDCQYLGIENI
MALRGDAMKEEKYFTPTKGGHTYASELVAQVQNLNEGKYLHDDIEMDNLPDFCIGVAGYP
EKHMEAPSLQSDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVEIAKAMGINIPIIPGIKP
IAVKRHLNILPPVFKIDLPQDLIDAVDACIDNKAVRQVGIEWAIQQSKELKEAGVPVLHY
YSMGKSDNVKAIARELF
>A0A7X3SEX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. Taur|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSILKPKFLSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWDNGIRHIVALRGD
LPPGSGKPEMYGADLVELLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPALRA
>R7BED4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:341|TrEMBL
MKIKDIINNKKVTVSFEVFPPKQWDKIANTKKVVDEMVKDKPSFMSVTYGAAGTTSGFTT
EIANAIKQGGVEPLSHLTCLTSTKEKINSVLDELEANGIENVLALRGDIPKDFEMGKNQY
YHNAFELVSEIKARNKFCIGAACYPETHPESKNRVEDIARLKEKVDCGVDFITTQMFFDN
EKFYNFREMCAIKEINIPIIAGIMPITNANQIKRSVELSNASLPVKFSKIMERFGENPDA
MKQAGIVYATEQIIDLMANGVNNIHIYTMNKPDVAHQIMEGLSAIINE
>A0A315B9V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus euhalobius|TrEMBL
MSLKTNVTYYPAMPSAFKEKLLSDEFIVTSEISPPKGVDVSSVFEEAGLVRDYVDAFNVT
DNQRAVMRMSPLAMGHLLKEQGLDIIMQFTCRDRNRLALQSDLLGAYAMGMENVCIMSGD
YPTKGDNPGAKPVYDLDSVQLLGTINRLEKGFDIAGNPLESVPSFTKGAVCNTEPDLPLQ
LMKLEKKARMGIDFFQTQAVYDIGHFETFMDSISHMEVPVLAGLIPLKSAHMARFMNEKI
PGIQVGDELIARMESSTDPAEEGLLICAEQVRELKKVCRGIHLMPIGHYRQITALFEMAG
LYEKD
>A0A7X5V821|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella shirazensis|TrEMBL
MPGFELICEVEPPTRPDLKKVRHQIGVMSAVADGFLIPDNHIGRATVSSVAVANEVQLMG
ARGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDDPAEGARTSQLTVRRMIEQTRE
TSYPGCNPFKVGAATRLTKVPRWKAEADFLYVQVSYDLDELLRWRDSADVEIPVYAGVMV
LASARMARNLAGLPQLTIPPSLIEAVESDRDAGVDHACEQILKIRDSGAFDGVHLIPVSR
YRQVTARLEGEL
>A0A373A7U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium OF09-6|TrEMBL
MKITELFKQGEFVVSAEVGPPKGIHIEGLLEEAKTYLSGITAVNVTDNQSSVMRLGSLAT
CKALKDEGLTPIFQLTCRDRNRIALQSDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKQLESGVDLGGNELVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVMAGA
DYFQTQAVYEPEKFIKFMEKASQFGKPVQLGIVIPKSAGMAKFMNKNVAGIHVPDEMIEE
LAKDKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKVPDLLKLAEI
>V4NFA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella multocida subsp. multocida P1062|TrEMBL
MSYAKEIDTLNQHIADLNGKINVSFEFFPPKNEKMESILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLEAAPHLTGIDATPEELIEIAKDYWNSGIRRIVALRGDEP
KGYAKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLVKMAAITNVKIPAWLAKNYEGL
DDDPTTRNLVAASVAMDMVRVLSREGVNDFHFYTLNRSELTYAICHTLGIRPSSE
>L1PY50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerostipes hadrus DSM 3319|TrEMBL
MKISEILKNKSTISFEVFPPKNKEGDISSIYSTIEGLAKLSPDFISVTYGAGGSTKGKTV
EIASVIKHEYGIESVAHLSCISSTKEDIKYECERLKEAGIDNILALRGDYPADATNFDPE
NLEFHYASELNEFIGEHFKGQFCLSGACYPETHQEADGFKKDLEALKKKVDAGAEYLVTQ
IFFDNDYYYRLVREARKIGITVPILAGIMPITNAKSLIRTTKMCGCTIPYQLSTMIEAHY
DNPEAMKEIGINYAAQQIIDLITNGVDGIHIYTMNRAETAQRVFDSIPAVLKELN
>A0A1H9PCG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. YR768|TrEMBL
MSLPSIHPNWDLPPKGMTDGYSLEMTAKDMEALVEAAPAMAAETPVAVTFLPGESLEARI
AATKAVRDLGFEPMPHFSARRLESGDDFESYLAAVVREAGVRRCFVIAGDPAEAAGPYSD
SMALIRTGAFERAGIKAIGIGGHPEGHPNMSREQTFEVLIDKCAEIASRNMAPLIVTQFG
FDAAPILQWLVELRARGIDAPVRIGVPGPAGIKTLMRFAARCGVGASTSVLAKYGISITK
LIGTAGPDKLVDALGQALGPQHGKVRLHFYPFGGLTRTVEWINDYTARP
>A0A0S4QJQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia irregularis|TrEMBL
MTAVGNAARTTARTVAECLASGRTSFSFEFFPPKTAEGERQLWTALREVEALQPSFVSVT
YGAGGSTRDGTIRVTERIATETNLTPIGHLTAVNHSVAELRQVIGGYAGAGVRNVLALRG
DPPGDPQAEWVRHPDGVAYAEDLVRLVRSLGDFCVGVAAFPDKHPRSPDLETDARFLVQK
LDAGADFAITQFFFGADDYFRLVERVRRLGCDAPIIPGVMPVTNVAQIVRMAQLSGAEFP
ADLAARLQAVADDPAAVRAIGIEVATELSERLLAGGAPGLHFITLNRSGATREIYRALNG
>A0A5S3SAI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. S558|TrEMBL
MALSLKEKIVDTNQGVYLIGTTPPKIGTDKAQLKIIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQARPFAFKQTVDPREYSHLLRNLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDL
QNVVLVGSPSSIGDIKLSLPDAYKALAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGIIPQRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKLIA
>A0A1Y0ERN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas serinivorans|TrEMBL
MTKLPISFEFFPPKTPEGLEKLRTVRQQLYVRQPEFCSVTYGAGGSTQAGTFGVVRQIQD
EGVAAASHFSCIGATRESVREELAQLQAAGIRRLVALRGDLPSGYGMGGEFQYASDLVAF
VREAFGDWFHIEVAAYPEMHPQARSPEADVQAFVTKVKAGADSAITQYFFNADGYFRFVD
EVRKAGVDVPIVPGVMPIINSSQLMRFSDATGAEIPRWIRGRLQGFGDDLTQIRAFGLDV
ITQLCERLRAGGAPALHFYTMNQSQATLEITRRLGWA
>A0A4Y3THQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio desulfuricans|TrEMBL
MKIAEAIERQSRPFYSLEFFPPKEREQWPAFFATVERLKAMDPVFASVTYGAGGGTQDNT
LDITAHLKNALGLEPMAHLTCVGATRERIAGFLARLREQGVENVLALRGDPPRGQQVDWE
TAEFRYASDLVRFVRNEFPEFGIGVAGYPAAHPESVSFSQDIAHTCQKIHAGADFVVTQL
FFDVREYFAFIERLKECGVEKPVLPGILPIQSLESIKRILALCGANIPGKLYLELEEADA
RGGAEAVREAGIAFAVRQIRSLIDGGAPGIHLYTLNKADMCLQIRDAVGAL
>A0A3T1CG93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania flava|TrEMBL
MSPTMDQMREAQRALETPLFSGLPGDIEVSFEFFPPKNEKMGETLWRSVETLAPLGPRFA
SVTYGAGGSTRERTHQQVVRIQNEANIPAAAHLTCVEATRDQVDEVARHYWDEGIRHIVA
LRGDAPDGQGTYRPHPDGYANAVELIAGLKRVADFEISVAAYPEVHPDSPDRQADLDNLK
AKFDAGATRAITQFFFDPECFFDFRDRAAAAGIEGEIVPGIMPVLSFAAVQRMSGLCGTA
IPDWMEGLFDGLDDRPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRPKVAA
>A0A7Y4ZZZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp|TrEMBL
METSPNKLGLSFEFFPPKTAEGMDKLRETRTQLSKFNPEFYSVTFGAGGSTRDRTMDTVL
EIQREGFQAAPHISCISSSKDEIRDLLHAYQAQGIKRLVALRGDIPSGEVSAGDFRYASE
LVQFIRGETGNHFHIEVAAYPEFHPEARTPAADLQNLKRKVDAGANSAITQYFYNADAYF
RFVEQCDALGIAIPIVPGIMPIYNITQLARFSSICGAEIPRWLKMRLEEYGDDMASLRAF
GIDVVSELCDTLLAWGAPSLHFYTLNQAGTISNIIHNISE
>A0A7Y1AMX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. WS 5078|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLMNTARHLATFNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVHVPAAPHLSCVGDSKSDLRGLLEQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDINNFVRKAHAGADSAITQYFFNADSYFR
FVERVQAAGVTIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A7W8D1U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalicoccus acidiformans|TrEMBL
MKIVEVLNQDKVTLSFEVFPPKKMDDYTKVEEAAHQIASLHPDFMSITYGAGGGTSQYTV
DLARDLYQRTGTEVIAHLTCVTSTREHVSHMIQSFKQAGIENIMALRGDIPKDGKVAHDY
SYAYQLIREIKEHGDFCIGGACYPEGHVECEHKKDDILHLKQKVEAGCDFLTTQMFFDNN
VLYNFLYRIREAGIQVPVLAGIMPITNKKQLSRSVQMSGTQVPERFKAIVDHFGDDPQAM
KQAGIIYASEQIIDLIANGIKHIHVYSMNKPDVAAAIQNNLSGILK
>A0A2R6ERY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QH_7_66_36|TrEMBL
MALRTRSVDKTGVEELLTSVRFELMPFESFEEEITHLPDDATIAITTSPQLGIETTVDRT
EEAAAAGYDVVPHVAARYVEDRDQLREIARRLTDAGVTDIFVPGGDREEPAGAFDSAHDL
LVALDEMPYEFEEVGITGYPEGHEFLDDDTLAEAMAQKAPYATYIVTQICYDPDAVIEWI
EEVRDHGVDLPVEVGIPGVMNYKRLMSISQKVGVGDSVKFLKKTTGVLGFVKQLVGSRGN
YEPDELVDGLASHVNDPAYDIRGLHVYTFNQTPDTEAWRRGRLE
>A0A5C1Q640|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerotilus natans subsp. sulfidivorans|TrEMBL
MTTTPAASLPLSLEFFPPKTPEGTARLAQVRRELYVLEPQFCSVTYGAGGSTQDGTIGAV
QAILDEGREAASHFTCVGATRESVRERLAQFKAMGLKRIVALRGDLPSGFGPMGEFRHAS
DLVSFIRAETGDHFHIEVAAYPEMHPQAKSPQADLQAFAAKARAGADSAITQFFFNSDAY
FRFVEEAQALGADIPVVPGIMPITNSSGILRFADSCGAEVPRWIRLRLQSFGDDSASIRA
FGLDVVTDLCEQLRCAGVPALHFYTMNASATVLEICRRLELLPKA
>J6CXR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella multocida subsp. multocida str. Anand1_buffalo|TrEMBL
NYPILFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLVKMAAITNVKIPAWLAKNYE
GLDDDPTTRNLVAASVAMDMVRVLSREGVNDFHFYTLNRSELTYAICHTLGIRPSSE
>A0A5C5SSG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reyranella sp. CPCC 100927|TrEMBL
MSPDTGPLSTSVPTSEFPARKPSKLVVSFEFSPPRTDTMAETLWNSIERLAPLQPAFMSV
TYGAGGSTRQRTHETVVRIKRETGIEPAAHLTCVAATCGEIDDVARAYWDAGIRHIVALR
GDPPRESGGKYVAHPGGYANAAALVAGLKRIGDFQISVAGYPECHPDSADDITDLDNLKR
KVDAGADRCITQFFFDVEDFLRFRDRATAVGVQVPIVPGIMPVSNFAGITRMAGMCGAKV
PGWLAALFEGLDDDLETRRMIAATVAGDLCRKLESEGVSAFHFYTLNRADLTYALCHLLG
VRPQARPRAE
>F2J4F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polymorphum gilvum (strain LMG 25793 / CGMCC 1.9160 / SL003B-26A1)|TrEMBL
MTEIRSRTIDEVQSACAPLRGPLWLAPWSLEATAPTAADIAALAPLVPPGTDVLLSALPR
IPHDEQIAAARLVRAAGLEPVLHLSARKFASEAELGHLLETACRDIGLRKVLVIAGDIDA
ARGPFASSLDLIESAPFRAAPLQSVGIGGYPEGHPFVADADLERSLRSRLDAIRDAGRAP
FLVSQFCFDAERILRWLDGLRRLEPALPVRIGLAGPASAATLMKVALRCWVDLPMRHART
ATRLLSSGTPDPIVAGLDAGLRPHHRSGPLQIHVYGFGGLVKAAAWAGEAARTARAGWTA
>A0A0P1ERR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shimia marina|TrEMBL
MTTPQVSFEFFPPQSLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRDLTREAVATLHK
SSGLNVAAHLTCVDASKAETLQIAEDFAQAGVSEIVALRGDPPKGSSRFAPHPEGFANSL
ELISALADTDKFTIRVGAYPEVHPEAADMAANVDWLKRKIEAGASEAITQFFFEAETFLR
FRDACAAAGITAPILPGILPIENWKGVRNFAARCGTSVPNWLINAFEKAERDGREDLLAT
AVCTELCSDLMDEGVDALHFYTLNRPELTRDVCHALGVTPSVRLQNVA
>A0A1G7ZMZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas sp. Nm132|TrEMBL
MRSQKNFSPTFSFELFPPQTPEGVEKLRAARQQLAQFKPKFFSVTFGAGGSTRDRTFETV
LEILAEGHPVAPHLSCIGSTRENIYSILSKYQENGIRHIVALRGDLPSGMAQSGEFRYAN
ELITFIRKEFGNTFHMEVAAYPEYHPQARSAQEDFRNFKNKIEAGADSVITQFFYNADAY
FHFVDMCEAANLNVPIVPGIMPINKFSQLVRFADTCGAEIPRWIRKKLEGYGDDIASIHA
FGLDVVTDLCEQLLKAGAPGLHFYTLNSAVLTTKIWQRLGL
>A0A0H1AQJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas sp. FCS-9|TrEMBL
MIPISFEFYPPKTDEQRAQLDRTARKLATHAPEYASCTFGAGGSTLSHTPETVRRLRQHH
GMEAAPHLSCVGGSREEIRELLKLYRAIGCTRIVALRGDLPSGMGQPGDLRHASDLVAFI
RSEFGDRFRIEVGCYPEIHPQAEDARKDLQHFKAKVDAGADAAITQYFYNADAYFHFVDS
ARRAGVEVPIVPGIMPISNFTQLRRFSEACGAEIPRWMQRSMAAHGDDAAAIRALGADIV
TRLCERLIAGGAPGLHFYTLNLAKPTQTILARLG
>A0A2U1ZM70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia paraffinivorans|TrEMBL
MRIALYTGRVTPTAPAPSIVERLSAPHRGPVPFSVEFMPPRDADGEARLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSVDELRALVGAYADQGIT
NLLALRGDPPGDPLGEWVKHPDGVEYAVELVRLIKELGDFHVGVASFPEGHHRAIDLEHD
TANLVNKLRAGAEYSITQIFFDVEDYLRLRDRVSKADPEQGAKPIIPGIMPVTSLASIKR
MAYLSGSVIPPAVEERFAKAAGDGLEENREAVRAVGIDFATETAERLIAEGAPCLHFCSL
NFAKATTEVLGRLGVDVDAALHVPA
>A0A2K1P1V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrotoga sp. 9PWA.NaAc.5.4|TrEMBL
MKVVEAIKQSKNPILSFEVIPPKVGGNINNIFEVLDDLIEFSPRFINVTKHANEIEFMEK
EGKIEKIIRNKRPGTVGISAAIKNRYKIEVVPHLLCVGYNKYQLEDILIDLNYLEFENVF
VIRGDKNRYTWKVEGEYEHASDLVRQISELNQGNYTCPLKKAFPTNFCIGVAGYPEKHVE
SPNLRKDLEYLKLKVELGAEFIITQMFFDVEYYKNFVKRVREIGIDIPIIAWIKPIESKK
SLYTIPKNFFVNIPQKVIQDFDEARSEQDEYKLGIKYTINLIKDLLEIKVPGVHIFTMGR
GKAVKEILRELKGVF
>A0A6I7Y663|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. SH7-1|TrEMBL
MKVLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKRLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAILNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6A7KWV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteitalea sp|TrEMBL
MRNMQDFREALDERVLICDGAMGTELYTRGVFLNRCFDELNLTRPDEVGDVHRGYVRAGA
DVIETNTFGANRVKLASFGLVERLGDINIAGVHLARHAARGATFIAGSMGPLGVRVEPWG
KTGLDEAEEYFREQAAALAEGGVDLFILETFRDVSELGAAVRAVGRVSAAPIVALLTTGE
DGSTHDGVPPEEFTPQLEAFGADVIGVNCSVGPAAMLDTIEHMAALTDRRLAAQPNAGRP
RDIEGRNIYLCSPEYMASYASRFVTSGVRLVGGCCGTTPEHIRQMRAAVGALPAPAARGQ
QSVGRPSEGRPLRGATDPVRAQGAAKPYRHDARTARPAVTPVPRAEKSSAAAAFARGDFV
IGVQLVPPRGYECGALLEAARTVKARGADFVYVPEHGNGVARMSAIAAALLVEQRTGIET
LLQYACRDHSLPAIQADLLGAHAMGLRNVLLVTGEPLRQHDYPDATLVFDVDSIGLTHAV
ATLNRGEDIGSQSIGRPTAFHIGVAANPTAVVPDHEVRRYRYKVDAGAEFLVLQPIFDAA
DLAAFLDRLGAPRLPAIASVQPLTSVREAEELAHEVPGVRVPAALVERMARAEETGSVVG
EGLEIARELIVALRPLTQGVLVVPARGELESALELVEGVKG
>A0A6G7TLB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leclercia sp. 29361|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMAKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7Y2PMT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldanaerobacter subterraneus|TrEMBL
MLKNEKLCNKLKEKKFVITVEISPPKGIDVTKTIEEARKLKGVADALNITDSPMANMRMS
PIALAHILQDHLNIETIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDNPSLGDTPQ
AKGVYDVDSVGLLKIIKALNSGFDYNGNKLDYPTSFCAGTTANPNDLRDEAIEKLHVKVE
AGAEFIQTQPVYDEEILFKFLDKVKDLKVPVLVGILPLKSYKMALRLMEKVPGIEIPEKV
LKRLEQGGKEEGINLSAEFIKNIKNEVAGIHIMPMGSVDFVFDIISKVEGIAISAKKVET
K
>A0A3M4CYV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. lachrymans|TrEMBL
MAIICGSGLVRXXXXXXDKSAPTKYVFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLT
VARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLL
AQYKDAGIKRIVALRGDLPSGMGMASGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQ
ARNFEDDLKHFVNKANAGADSAITQYFFLHSRAVSGFVKVFHAKFQDDNAKWWTSLMVEE
INSKVEITPRNLPRFDARSYTFIPRRAHGDGGDPPVDPPSSGAPDFGEDVHFDYQFETTD
YWTLTVINPETQQWVNFETLKFLPSKPDGDGINTSIILWESELEEEKMFSWTGFIFDDPA
VIGDVSKVNFDEALQDVMGDVHTLDIDVKMSLFETGKLVISLHRLRGLKYIPVGDSRDKL
MGEIVVLLLDKQGNAHKRRIGFLATGVGRRNRLMHTLYSV
>A0A7G3EIC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. 69-14|TrEMBL
MTALSFEFYPPKTDDQRAQLDRTASKLKVHAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLQAAPHLSCVGGTREEIRELLKLYRAIGVRRIVALRGDLPSGMGFPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLRHFKAKIDAGADAAITQYFYNADAYFQFVDA
AGKLGVDVPIVPGVMPISNFSQLRRFSEQCGAEIPRWIAKRMQAYGDDVDSVRAFGADVV
AALCERLIAGGAPSLHFYTLNLARPTSAVLQRLGHG
>A0A6J1W139|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Notechis scutatus|TrEMBL
MELAEKTPIARAFTMVNEILPMSNGLGTRSDGGNSSSSGESSQNSSRCSTPILDTERHER
LREKMRRRQESGDKWFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSD
KETSSMMMATTALNYCGLETILHMTCCNQSRETITAHLQKAKRLGLKNIMALRGDPVGEE
WEEELDGFNHAVDLVKHIRQEFDDYFDLCVAGYPGGHPEANSYIDDLKHLKEKVSAGADF
VITQLFFRTETFLKFLMDCQAIGISCPVVPGIFPIQGYHSLRQLVKLSKLVVPQEIKDVI
EPIKDNDAAIRNYGIELAVKMCQELLESGLVHGLHFYTLNREVATMEILRRLGLWKEDPR
RPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYY
LFYLKSKSAREELLKMWGEELTCEQSVYEVFRCYIAGEANRNGHKVTCLPWNDDPLAAET
NLMKDELVKVNRRGILTINSQPNINGKPSTDPIVGWGPEGGYVFQKAYLEFFTSAENIKA
LLTVLKKYGERVNYHIVNVKGENVTNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWK
DEAFTLWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLESCLWQVLEDTYEQLN
SPGEEAKTSGV
>A0A7R8NJ47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. KY75|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A290Z263|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinosynnema pretiosum|TrEMBL
MTSVLERLAGKTPAFSVEFFPPRDAADEQVLWRAIRELEALDPAFVSITYGAGGSGRDRT
IRATGRVAQETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDPNGEWT
AHPQGLNYAEELVRLCRELGDFCVGVAAFPYGHPRSADLDTDTEHLVRKLRAGADFAIAQ
LFFEADDFLRLRDRVVARGCDAALLPGLMPLTTPRTLAKTVELSGAPVPDSVARALDPFT
GDPAGFRRAGVELVTRMGERLLAEGVPGLHFYTLNRSKATREVVANLGLAPARATA
>A0A4Q4DJB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. L-9-10|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSVTYGAGGSTRAGTVRA
TERIAADSTLTPVAHLTAVGQSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVKHP
DGVRYAVELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVDKCRAGADYAITQMFF
DPEGYLRLRDRAAAAGCETPIIPEIMPVTSVKMLERLPQLSTAVFPPELKERILSVREDP
AAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYENLGLHEQS
>A0A4Y7ZS36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychromonas sp. RZ22|TrEMBL
MNTVIKSDYISASHLAQLNQNIANINQHVGVSFEFFPPASIEMENTLWDSIERLKTLKPK
FVSVTYGANSGTRDKTHEIIKDIKSKTSMVAAPHLTCIDATKDELRNIARDYWQNDIHSI
VALRGDIPKGELKPHMYSTDLVILLKQEGDFDISVAAYPEKHPEARSAQFDLEVLKAKFD
AGANCAITQFFFDAETYLRFRDKCIKQGIEEDIVPGILPVSNYKTLVKFAGMTNVHVPDW
MHKLYQGTDNDPITRNLIGANQAIEMVKVLSQEGVKDFHFYTLNRSDLSYAICHSLGLRP
NSN
>A0A1I3MDD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquamicrobium aerolatum DSM 21857|TrEMBL
MAEPRLSRRADLGERIKVSFEFFPPKSDEMESRLWETITRLETVSPHYVSVTYGAGGSTR
ERTARTVGRILAQSSLKPAAHMTCVDATRDEVDAVVREFAEMGVTRFVALRGDPVSGVGE
AYRPHPQGYSNGAELVAAIRRIGDFDVSVSAYPEKHPESADFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGILPIHNFGAVANFSARCGAHVPAWIAERFA
GLERDPQTHALVASAIAAEQVLDLVERGIEEFHFYTMNRADLAFAICHLIGIRPAPEASA
AAAA
>A0A2N6NU48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beauveria bassiana|TrEMBL
MHIKDLLAETKRSGKPSFSFEYFPPKTAQGVQNLYDRVDRMYNFGPQFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGMEKVNDALRKAYKAGCTNILALRGDPPRAQEK
WTATEDGFQYACDLVRHIRATYGDHFDIGVAGYPEGCDDNDNEDELIEHLKYKVDLGGTF
IVTQMFYDVENFIRWVGKVRAAGITVPILPGIMPIATYASFLRRCKHTGCKIPQSWLDLL
EPVKNDDVAVREVGKKLVVDMCRKLMAADIHHMHFYTMNLAQATRMVLEELNWTPSAERP
LQQALPWKPSKGFGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRLKWGEPKTLRDIANTFVRYLNQEIDSLPWSEAPLTSEADSIKPALIE
LNQRGFLTINSQPAVDGVKSSHPVYGWGPANGYVYQKGYIELLVSPKIVDQVIQLVNTNP
SLTYYAVTKNGNLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFDAKSPSRVLVESVMDNWYLLNIVNNDFHDNTTIFELFRDLKVDGLDTPIAVEAEAP
VAAEAEKPAAAQAEAVA
>A0A4R2JKE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldanaerobacter subterraneus|TrEMBL
MLKNEKLCNKLKEKKFVITVEISPPKGIDVTKTIEEARKLKGVADALNITDSPMANMRMS
PIALAHILQDHLNIETIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDNPSLGDTPQ
ARGVYDVDSVGLLKIIKALNSGFDYNGNKLDYPTSFCAGTTANPNDLRDEAIEKLHVKVE
AGAEFIQTQPVYDEEILFKFLDKVKDLKVPVLVGILPLKSYKMALRLMEKVPGIEIPEKV
LKRLQQGGKEEGINLSAEFIKNIKSEVAGIHIMPMGSVDFVFDIISKVEGIAISAKKAET
K
>W8VZD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonlabens marinus S1-08|TrEMBL
MKITDHIKKAKKTLFSFEIIPPVKGKSIQELYSNIDPLMEFKPPFIDVTTSREEFIYIEK
KNGLLEKKLTRMRPGTLGICAAIQNKYDVDTVPHLLCGGFTQQETEYLLVDCQYLEIDNV
MALRGDARKGDKRFECTEGGHEFAIDLVKQVEQLNKGHYLHDVIEISCDVDFCIGVAGYP
EKHEESPSMKTDLKRLKNKVDAGAHYVVTQMFFDNKKYFEFVKAARDIGITVPIIPGIKP
IATKRHLQLLPQTFHLDIPQDLVDAVENCKTNKDVRQVGVEFCIEQCRELLAHNVPVLHF
YSMGKSDNIYDIAKAIF
>A0A399X0C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MTARTAHCWRLADNTFTANRFRFVDLRDDLYEINRAGARIAKAACGDGAVILGAIGPAGK
PMYPLGSISSSEVIESACEQARALEEGGVDAFLLESFLDLDELERVVEGVRQASNLPIIA
SKAFIEDGEAISGGLPYQSAKRMAAMDVAAVGANCVVGPQRMLDLVRMMTEATSKPVLAY
PTPGMPTLIKGRVAYDTDPTYFAKACRRLAEEGAALIGGCCGTTPDHIRALSQELGRSPV
QRAKRASVATRDYETKPLESTPRTEFGERIARGESTYSVELDVPRGLKLDRLMADVEAVR
AAGAHTINISDGARARLRMNPTAVCHLIQSTTGAETTMHFSCRDRNLLAIQADLLGCHAL
GVRNVLAITGDPANIGDYPSATSVFDVDAVGLVRILGRLNEGIDLAGYGIGRKCGFTICV
AFNPGSPRPEVELVRLQQKADAGAHAVYTQPVFDESLVEIALESCKKVGLPCLIGVMPLR
NARHAEFMHNEVPGILVPERLRAALADAPDDEAALDLGIGQALRLARLAKSGGAGVYLMP
PANRITAAVKVLEGIR
>A0A7C4Z2D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MSGIVELLRGADVLVCDGAMGTMLHERGIHFEHPYEYANITHPELVASLHEEYVRSGASM
IETNTFGANRFKLAAFQREGLVKEINAAGVKAARKAAGRSVLVAGAVGPIGKPLMPLGRI
DPEEAAAAFREQAEVLLESGVDLILLETFSDIEELKLAIRVVQELADIPIIAEKAFTEDG
ETLAEGLPARVAAELSNLGLVAIGANCAVGPQRMVEIVRMMVSSTELPVCAMPTAGLPQI
IDGHVHYNATPEYFARYGRILAEAGASIIGGCCGTTPEHIRALATAVRGLSRTVRQTVEP
AQPSAKPVSASSAVVEVVRPQPSRLSQKLGKKYVVAVELDIPKGSRIDKVLEGAQALRDR
GCDCIDISDGARARLRMNPMAVAHLIQEQVGIEVMMHFSCRDRNLLAIQSDLLGAHALGL
RNILAITGDPTQVGDYPTATSVFDIDSIGLVRILSRFNEGIDLAGNSIVEPTAFLIAVAF
NPTAPDFAHEVERLRRKVGEGAQLVYTQPIYELSVLERAVAETQKLGVPMLVGILPLRSY
RHAEFFHNEVPGIYIPEEIRRRMAGMSDQDARAYGMEVAKELLTQARHMTAGAYLMPPFG
NYKIAEELMEAI
>A0A7Y2EJ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIKNANGNTQFTFEILPPLKGQNIDFIFDSIDPLMEFNPPFIDVTYHREEYIYKE
LENGLLQKQVVRKRPGTVGICAAIQNKYDVDAIPHILCGGFTKEDTENFLIDLGFLGIDN
VMALRGDAVKSETYFTPEREGHTYASDLVKQISKLNEGKYLEEELQNTTPTDFCIGVAGY
PEKHLEAPSMESDIYFLKKKIKKGATYVVTQMFFDNNKYFNFVEKCRESGITVPIIPGLK
PLATKKQLNMIPHRFSVELPDDLVMEVVKCEDNKAVRQVGIEWCIAQSKELIKAGVPVLH
YYSMGKSDNIKAIASEVF
>A0A8A4TUR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfidibacter corallicola|TrEMBL
MLRTDYDYLIQERVLVIEGNMTAELSRRSRARIVHPAFHILEHPDLVRSIHQDFAVSGAH
VLVTATAESNRLALEGEPLRAEYEAINRKACEICRAAASAQQLVLGGLGPTGALLRPYGR
LTEKDYRDIYKDQASLLLDAEVAGFILEGFSSLIEAEQCVLALRELSACPIVACMTFLED
GCTQFGDNVDDCFSTLMEVGADTVGIQGTLGPLEIEGILAQKKTNYPLCVRPNAGYPVHL
GNTVSYLSSPEYVAECAELFLSQGAVMVGGAAGFTPDHIRAVADRVRGSFPQVAKKGSSV
VASTAPDASDTPRHATRNGPSLCEKLGKQPILSVELEPPRGMEIESLIATIEKLKPYGLD
AINIPENPLARARISSIALAKVIRERTQVESIAHITCRDRNLISLQAELLGAHVLGVRAI
LALTGDPARIGDYPSATSIFDVNSLGLVEIMSRMNLGKDFGMNDLGEPTRFQIGVAANPL
AENLDEEMRYLEMKIRRGAHFVQTQPIFDPAAVAPFLQRIAPYEVPVLFGVMLVRDFRHA
KFLNNEYPGIHIREADMARFQNADESQQAELGIRFAAELINELRPMSGGVYVMPSFGEAH
RLEGVFEKLD
>A0A7X6XJ55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MAIDLDQLLAAGVVVLDGAMGTLLQQHGIPHGHPYDFANLTHPAIVQGIHAEYVAAGAHI
IETNTYGANRFKLSAHGLGERVAEINAAGARLARQAAEGRALVAGSVGPIGRHLAPVGKV
SPSEAAAAFAEQVQALLEGGVDLFVLETFTDLEELRLAVDAVRAACALPILAHKTFIEDG
ETLAEGLPRRVVAQVADWGLTAFGANCTVGPQRMLTIVQGMAEATTLPLSALPTAGLPQI
IDGHVRYDATPEYFAHYGRQMVEAGARLVGGCCGTTPAHIKALAQAVRGVVPGSRRVTVT
GPATSEAAPARETQRSRLADKLGRKYVVTVELDVPRGLDMAPVLRAAEALRDQGCDCIDI
SDGARARLRMNPMVVARQVQELVGIEVMEHFACRDRNLLAIQADLLGAHALGLRNILAIT
GDPAQIGDYPTATSVFDVDSIGLVRILRAFNEGVDLAGTPLGEKTAFLIAVAFNPLAPDL
TLEVERLRRKADEGAHLIYTQPIYELGVLERAAREAARVNLPLLVGVLPLRSSRHAEFFH
NEVPGITIPEPIRRRLATLEGDDARRYGVEQAQAFLREARSLSAGVYIMPPALSPHVAGE
VMEALEGCHLTWH
>A0A091H4S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buceros rhinoceros silvestris|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFPFLKFMK
DCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVEL
AVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWKEDPR
>A0A3M2AZI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MTREAFRERVAQGALVADGALGTMLALRGVPQPYELATLTHHEVVRALHREYYEAGARLI
ETNTYYANRVRLLNLPERGGELTPAYSLLEQFGSPDELVRRINQEAVRLARESVGEDALV
FGAVGPVGKPLEPMGEVRLEEAEQAFEEQIRALLEGGVDGLILETFIDPQELALAIRVAR
RLAPQIPVIASKGFVEDGETLMEGLPERFAEQIQQLDVDAVGGNCIVGPQRMLDIVRMMT
SATELPISAMPTPGLPQLVRGQVIYDIHPDYFGKYAARLVEAGATIVGGCCGTTPEHTRA
IAHAVKGLKPKRAAAPTTIRTREREPKAELPTAAPSHLSQLLGKQRVITVELDLPRGLKI
EKVIEGARMLKEHGVHMIDISDGARARLRMNVIATSHIVQREAGIEVMMHFACRDRNLLA
IQSDLLGAHALGIRNVLAITGDPAQIGDYPTATSVFDVDAIGLVRILRRFNEGRDLAGNS
IGVYANFTIAAAYNPLAPDLDAENDRLRRKIAEGAHLIYTQPLFEMPLVERTAELLQKLN
TPWFVGVLPLRSARHAEFMHNEVPGIRIPEPILRQMTEAPEDSALQVGLEIAQTFVRQAA
PYAQGIYLMPPAGNAQIALRVIEALD
>A0A7Y2Z2I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIAKGNGKTQFSFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYVYKE
MENGLLQKKIVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKTETYFTPEKEGHNYALGLVQQIAALNRGEYLDEDIQNQAQTDFCIGVAGY
PEKHIEAPNMDSDIHFLKKKLKHGASYIVTQMFFDNEKFFNFVNKCREEGITAPIIPGLK
PISTKKQLNLIPHRFFTDLPEELIKEVLKCSNNQEVREVGVEWCVQQSKELIAEKVPFLH
YYSMGRSDNIRSIAEQLF
>A0A6I5H7Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID486|TrEMBL
MALGTASTRTDRARTVRDILATGRRTYSFEFSAPKTAKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCDTPVIPEILPVTSVKMLERLPKLSNAVF
PDALKERILTAKDDPATVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHHPPRA
>A0A7K4ZPH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Centropus unirufus|TrEMBL
MVNETQHTCSTSSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDVCVAGYPKGHPEAESYEADLRHLKDKVFAGADFIITQLFFRAETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRSYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>H6CK56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Aloe-11|TrEMBL
MKPDLRTVLNRELIVGDGAMGTYLYQLGFPVNTSYEELNMTSPDVIADVHSQYLNAGARL
LETNTFSANDYKLARFGLESRVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
LELARNYDQQIDALLSEGVDGILCETFYSLDEMRIALHGVRKYSDIPVICQFAVDQVGRT
QDGFLVAEAFSVLRDEGADILGFNCHSGPQGIMSVMEQLKGPLSVPLSVYPNAGLADYVD
GHYVYGATPEYFGECAASFVDLGTRLIGGCCGTTPDHIAAISKALSGLQPPPLAPREVLL
KESIHVAEPEPTVDGRERGNGRYASKPNIVETVKERHTVIVELDPPRDLDITRFMQGAHA
LKKAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFD
ALGIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVV
GAAFNPNVKHLGKAVQRLEKKIASGADYIMTQPVYDRELIAAIAEETRHLEVPIFIGIMP
LASGRNAEYLHNEVPGIQLSDEVRARMSGLEGPEGRAMGVSIAKELLDTAMEHFNGIYLM
TPFMFYEMTAELTSYVWQKSGRVQAPLFRL
>A0A7R8WIJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprideis torosa|TrEMBL
MNMTLEQAAQQRILVLDGAMGTMIQQHKLEEEDYRGDRFKDFHTALKGNNDLLCLTKPEL
IGQIHRDFLEAGADLIETNTFNANRISMADYDMQDLVEEMNTTAVQIAKEAAQEYSKKNP
DKPRFVLGAMGPTNKTASISPKVTDPGYREVDYEFLGDVYREQAMALIKAGADALLVETI
FDTLNAKAAFHGIKLAMEEVGKKVPLMASGTITDKSGRTLSGQTTEAFLISLMHVDLFSI
GINCALGAHDLRPYIKVLADKAPFRVSVYPNAGLPNAFGGYDESPESMVQEMRYFLDENE
VNIVGSRKFLRLIQEEKYEEALDIARDQVEGGAQILDVNMDEGMLDGKAAMIKFLRLIAA
EPDIARIPIMIDSSKWEIIEAGLQNVQGKSVVNSISMKEGEALFLEHAKKVKAYGAATVV
MAFDKDGQADTYQRRIDICKRSYDLLVGKLDFNPKDIIFDPNIFPVATGIEEHRSYALDF
FKATQWIKENLPGALVSGGVSNVSFSFRGNDTVREAMHSAFLYHAIKHGMDMGIVNPTML
EVYDEIPKDLLERVEDVLLDRRDDATERLIDFAEGLKGQTKSKEKLLEWRSWSLDKRIEH
ALVKGITEFVDEDTEEARQLYPTPLEVIEGPLMRGMNVVGDLFGEGKMFLPQVVKSARVM
KKAVAYLTPYLEAEKAKNNDLSKAHKILLATVKGDVHDIGKNIVSVVLSCNGFDIIDLGV
MVPSERILEEAEKHQVKLIGLSGLITPSLDEMVDFAKLLKESNLNMPLLIGGATTSVAHT
AVKILPEYAEVIHVKDASKSVPVATSLLGVGKEALLAETQKEYEKIRKGYLERSEKKSYI
AIEEARNNRLQVAFDKIIKPQKLGVFEEHVLLEQLIPFIDWTPFFQTWELRGVYPKILSD
ATYGEEAQKLYNDAQEMLETILDKELCEPKGVWGLFPAHRVEKDSVLIDHNQHSVRFDFL
RQQAEKKEGQPYYSLCDYIASAEEAKEDYIGCFAVTAGSGLEKFAKEFEEQHDDYNSILV
KALADRIAEAFAEYLHWRIRTDHWGYAADENLSNEELIKEKYQGIRPAPGYPACPDHLEK
QTIWDVLNVEKHTEEYIYKKHSNGLLERKATRKRPGTVAICAAIQSHYKIDAVPHIICGG
FTKEDTENALIDLNFLDIDNVLVLRGDPPKGEGNFTPTEGGHHYASDLLEQVVDMNQGKY
LDEEVENAVQSNFCIGVAGYPEKHFEAPNLATDIDYLKLKQDKGAEYIVTQLFFDNQKYF
DFVEKCRAAGISIPIIPGIKPLATKQQVNILPNVFHIDLPEELSKEALKCADNKAVREVG
IAWCIQQCKELMDFGVPVLHFYTMSKAGMTKRIVKEVF
>A0A7Y2H647|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTDHIEKSNGETLFSFEIIPPVKGHNIQELYDNIDPLMEFNPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYNVDTIPHVLCGGFTKEETEYLLIDCHYLGIQNV
MALRGDAMKEEKYFEPTRGGHAYASGLVQQIQKLNCGEYLHEVVERDHCADFCIGVAGYP
EKHMEAPSLKTDLRRLKQKVDEGAHYVVTQMFFDNKKYFDFVRAAREEGITVPIIPGIKP
VAVKRHLQLLPQVFRIDLPQDLVDAVEACKNNKQVRQVGIEWAIAQSLELKEAGVPVLHY
YSMGKSDNIKAIAEAVF
>D1B0C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurospirillum deleyianum (strain ATCC 51133 / DSM 6946 / 5175)|TrEMBL
MLESFIEKLKHDSLLTLETTPIHEPTFEPIIEKIAQLGLDKKVDGFSTTDNPLARLKYNA
LFGALKLQNRFHKPVIATMSMRDRNKLALQSDLLGANENDLRTILCLTGDPASASDQPAL
KGVFEGNSTLLMDIIQCFNAGIDYSGKPFKTQPKPIYPFAVCNAHANTPRHLMKKMATKM
SHGAVGIITQPVYSMENATMLVELLKEAKKEIGKETHEAELILGFFPIIKLRTAQFLSAH
VPGVHVPTLWMEKLAHAKKISEAEEHKVGFELSLQTFRMLKKVHPKIHMMSANNFELIAD
LLAD
>A0A2E0UD12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MFENNRPDKKIQQQLLEGMTYELIPLKNVHDQAKFLPQNSTMSVTCSPAKTIDDTLDLCE
SFSADGHITIPHFAARMVESEEHVDSIIDRVHKLGIRKIFVIGGDADQRGPFYDAPSFLQ
ALVARKPDIDTIGIGSYPDGHADIPNSSLDQALFEKQEIILGAGYEGYIATQMCFDAKKI
AEWLREIRKAGISLPCHLGVPGAVDTKRLLTISLRLGIGHSTRFLKKNRATALRLLSPGK
YDPNKLLSPLSRNASDLGITGVHCFTFNSVDTTEEWRQKAIKKLSS
>A0A0F2E4Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. tigurinus|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVVPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3L8C4F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ketobacter sp|TrEMBL
MNSQKQHEKRFSFEFFPPKTDVGVEKLNLVQQELAEKKPSFFSVTYGAGGSTRDRTFETV
MNVKAKTGIDAAPHLSCVGDTKAQLAQLLTQYQSNGINRIVTLRGDLPSGMGASLGELKY
ASDLVAFIRQQTADHFHLEVAAYPEMHPQAKSMEADLQAFKTKVQAGANSAITQYFFNVD
AYKFFVDSCEKMGLDLPIYPGIMPIINYDNLMRFSGMCGAEIPRWIRMRMEGFRGDEQSI
KQLGEEIVTSLCEELLDMGAPGIHFYTMNQAEPTLAIWNNLGL
>A0A0P1FJG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobius autumnalis|TrEMBL
MTVPSVSFEFFPPQNLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRDLTRDAVATIHK
HSGLKVAAHLTCVEATREETLAIAEDFAKAGVSDIVALRGDPPKGSGGFKAHNDGFRSSV
ELIEALAQTGQFNIRVGAYPEKHPESPDHQADVEWLKRKFDAGADEALTQFFFEADTFFR
FRDACAKAGIEDKIIPGILPIENFKGARNFAKRCGTSVPDWVAEAFEKAERDDRHDLLAT
ALCTELCSDLIEGGVDSLHFYTLNRPELTRDVCHALGVTPKVSLENVA
>A0A5B8I5I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya poaceiphila|TrEMBL
MSFFHANHREALNQNLAELQGRINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPPGGGKPEMYASDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFE
GLDDDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPIASA
>A0A5A8CK88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cafeteria roenbergensis|TrEMBL
MAGAPRKVSDMMADAIAAKTPFYSFEFFPPKTDVGRENLFLRIDRMSILEPIFVDVTWTT
AGDGKDSRDGTFSVCEYAKQYAGLTPMLHLTLTGLTRADLLRQLQRARDAGIRNILALRG
DPPKGATEWRPCENGLSRAEELVRLIREEHGDWFCVAAAAFPEGYKEPSVPRGGDRPRAG
DDGDAAAAAAGSADGAEGAEGAGGAVDAAARDVADRDAAVAAAAAKVAAGAEVLLTQCVY
DVEAYSGFVAACRAAGVPESVPIVPGVLPVHGYEAFRRMTAYTGVNVPAELQDALDAAAV
SGDDEAVRREGTARVSALCRALLEAGAPGLHFYTLNLEMATRAILKDVGLCRGAEARRLP
WRPLGDGPGALTQVRPIFWANRHRSYVERTRNWDEQPTGRWGDGQSPAFGALSESHFGGP
GAAQGTSEERRAIWGEAEALDGEGPVLEVFARYLEGQVPRLPWCDQALLPETAPIRERLV
RLNRSGFCTINSQPRVNGARSDDPHVGWGGAGGRVYQKAYVECFCSPARLAALMEAAPAH
PSITFTAVDASGNLYTNCKRRGVQAVTWGVFPGKEVLQPTVVDEAAFLAWKDEAFQLWAS
VWADAYPEDSPAAEVLHGIATSWYLVHVVDHDFVAGDVFRPFEAATAALRLASD
>A0A378MWJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mannheimia haemolytica|TrEMBL
MLRSRLGWVKMYEGLDDDQTTRNLVAASIAMDMVKVLSREGVNDFHFYTLNRSELTYAMC
HTLGVRPDLTTA
>A0A094S4E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium odoriferum|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWESGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTTMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A2E9J7H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MKSTQLRFLDEMTYELIPLKNVHEQGEFLPKSSTISITCSPAKDIEATLELCEKFLAKGH
TTIPHFAARMVESEEHVTRIVKRVETLGIETVFIIGGDADQRGPFTDAPGLLRSFLDNNP
SIKTVGVGSYPDGHPVIPESALAESLIKKQEMILQSNLNGYMATQMCFEANTISSWLKNC
RKAGVTLPCYLGLPGAVDMKKLINISLRLGIGVSSRYLKKNRKSVFKLLSPRGYNPNKLI
VPISNDAEELNIAGIHCFTFNAVESTEAWRTKAMGRLT
>A0A081PGR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter antarcticus 4BY|TrEMBL
MKITDHISNAGDKTLFSFELLPPLKGKSIHEIYKAIDPLMEFNPPFIDVTYHREDYIYKQ
HTSGLLEKVSYRKRPGTVAICAAIMNRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARQADSGFIPTPGGHAFATDLLGQVKSMNEGRYLFEDHSAFQTNFCIGVAGYP
EKHFEAPNLKADFKYLKQKVDMGAEFIVTQMFFDNAKYCEFVANCRANGINVPIIPGLKP
ITSSKQLISLPKIFHIDLPEDLTEAVQACKNEEAVKEVGIEWMIQQCKELIKVGAPVLHF
YTMSNPEPTKRIARAVF
>A0A7C2QIK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetia bacterium|TrEMBL
FIITQPVFDVESFFSFMKKIENTGLPVIAGIWPLASYRNALFMQNEVPGVVIPDSVMKRM
ERCRSKEEARREGVMLAREMVTAIRGAIAGIQVSPPFGRLATALAVLARTDAEAEALL
>A0A3B0VFY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKSASRLEQVLKGGHFAVTGELGPPKSSDIEVVRNKARLLKGHVDAVNITDCQTAIVRMS
SIAAGLVAMAEGVEPVIQMTCRDRNRIGMQSDILGAAALGAKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQMLGMMRSLRDDQQFQCGEKIKDCPPRLFLGAAANPFAGPPDFRAARMGKK
IANGADFIQTQIVYNVEKFARFMEMARDLGLPEKAYILAGVTPPRSLGMARYMKKFVPGM
DVPDAVIERLRGAADKEDEGINICVDIINQVKEIKGVAGVHIMAIEWESAVPEIVSRAGL
DERPVIEDLIIAPNLTTPETIVVQGSAEAAAVVEEVTETAAPEAADLGEEILARARQEAS
EIVAAAQAQAAEIGTDRKVVQTTDDAGEHIMNEKERVMALESVKMGLDALKHAYGLNDDQ
FNALVKFISAQEILVKEPPVVETAAPVAPTPAPAASAPPSPAVPASTPPAAVEDTKTMDD
AKEAAAVKEAEEAKKAAAAKAAEEAKKAADAKAAEEAKKAADAKAAEEAKKAADAKAAEE
AKEAAAARGAEESKKAAAAETAAPAVPTLELEKTKLAERAAKIAPDNYTQAYNGVIRETV
LGNDDNSVTVGGSKALPFQLFEGEIPHKQLIAMDVVDAGYEDWPEPLSRHFADVLGNPVA
WAQKCVKEYGAEALCISLASTDPNGLNRDSAEAAKTATEVIQAVDVPIIVWGCGNADKDT
DTLRELTAGIGGKKVCLAPLSDANYRSLGATAMAFQHPIVAASPIDVNLAKQLNILLENL
GVSLDTVMMDPSVGALGYGIEYTYSVMERIRLAALTQQDEKLQVPIICNLGREVWKAKEC
RLPTDELLGDQERRGVMMEAITAACMLLCGGEVLIMRHPRAMDLAKELINSLLG
>A0A7V8F5V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter sp|TrEMBL
MPAISFEFFPPKTDEQRDQLDKTVRKLKRHSPDYVSVTFGAGGSTLSYTNETVKSIRSVH
GLSVAPHLSCMGGTRAEISALLDEYKESGCRRIVALRGDLPSGMASPGHFRYAAELVAFI
REHYGNHFHIEVAAYPEIHPQAENALVDLQHFKAKCDAGADGAITQYFYNPDAYFRFVDD
VTKLGVTIPVVPGVMPIANFSQLRRFSEQCGAEIPRWIVKRMQAHGDDTQAIRELGADVV
AELCQRLLDGGAPGIHFYTINRARTTEAVLERLS
>A0A8J5E6C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yarrowia sp. E02|TrEMBL
MSTITKLIAGLKPDEKFFSLEFFPPKTQNGMANFRARLARMAALKPLFITITWGAGGSTA
KKSLDIASECQSMGLDVCLHLTCTNMDPALIDQALEAASKAGICNILALRGDPPRGEEYW
QPASPEFQHAADLVKYIKKKHGDKFCVGVAGYPEGHVDGSDASHQDVQHDLPYLQEKVEA
GADFIITQMFYDDNKFLEYNKAVREFSPILKDITIIPGLMPINTYTSFVRAARLSHASVP
PAILDRIQAVPTGNDQQVKDIGVEVVSDIVNDVYTKTNKTVRGFHFYTLNLERSVARILE
RSGFLTVEEDIAVEEGTGSTASTTPNKTPLRRRSSASHRNRVVDDARHHPDAPKEEPDLT
TLALAIASGEGAVGREAVWDDFPNGRFGDSSSPAFGEIDGYGPSIHVPPARALELWGYPV
DDADLSKLFADTIVGKLPFMPWSDQTLSPETMLIQEQLMELNQKGIWTVASQPACNALKS
DDNIFGWGPKGGYVFQKSFAEFFISPEQWKKLKPVLDAQDGLVSYYVAKSDQLVDTNVAE
RASNGVTWGVFPNREIVQTTIIQEDSFDAWREEAFSIWSEWRALYKKNTASFKLLDKIIN
EYLLVTVIHHDYVEEDGLWELLGSV
>A0A3B0RHF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MEGTEKSNLQKTLESGEFAITAEICPPRGTDIKHFIEKARMLKDHVVAANVTDNQRAVMR
LSSLAASAILVREGMEPVYQLTCRDRNRIAMQSDLMGAWTLGIKNVLALTGDHVNCGDHR
EAKPVFDLDVVQLVETITRANNGLSLKGRELRGGTDFFTGAVVSPEADPFETEKIKFDKK
VRAGARFFQSQAVYDMDRFKRFFDEAEKTGAKILAGILLLKSSKMAHFLNKNVPGVMVPQ
ALIDEVDQAPDQLEKGIEIAARQVKELRGYCHGAHIMAMSQEISVPKIIALS
>A0A150T3V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
MSRTRPEAPFLDAIRRSILVFDGAMGSLLYERGVFVTQNFEQLNVTRPDLVKRVHADYVA
AGANVIETNTFGANRFRLERYGLVNEVRNFNLAGARIAREIAGGDAYVAGSIGPTGLVPG
VAKRDDLAAAAATFAEQAGALAEGGADLLVLETFRHLDEIKLAIEAARQAAPGLPVLASM
TFDTSGVVADGSEPERVARTLRDWGVDLLGVNCGDGPQLSLAMAERMATAGLPLCVQPNA
GLPRTVDGRLLYMATPEYFDVFARRMIQVGAAMIGGCCGTTPEHVKWMAKSARMLRGSAV
PEVTSRPHVTMDAPTGSEPTPLGERSPLAAKIAAGKFVVSVEVNPAPGLSPESALSAAKM
LIDNGVDVVNVADGPRATARMTNLAFCSLLVQRYGIEPILHVCGRDRNLIGQMAHLLGAH
AIGIKNLVIITGDPPKVGDYPEATAVYDLDSIGLLHMASTMNRGLDPAGKPIPGGKTSFL
LATGLEPGAPDLDKELARLERKRAAGADIIMTQPIFHQDLLEKVLRRIEHLGMPVLVGVL
PLVSYKNAEFLHNEVPGMQIPEEIRERMRKVPAGPEARKEGVKIAREMLFSVRDRVQGAY
LMPPLGKYELALEVLDGLKTS
>A0A212JBZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Eubacteriales bacterium|TrEMBL
MDIRSHLAQGRPLLFDGAMGTCFAALPGRAGERCESANLDHPEEILSIHRAYLDAGCQAV
KTNTFSVGVDLAQGNDALARGLIEAGARLAREAAEPYGAAVFADLGPAPQSQDQGPAELY
LRQADLFLAQGLTHFLVETLPSDEGIPELARHLKSRCPEAFLIVSFAVGSDGVTREGRVG
RELLRRIAALPEVDAVGYNCVSGPSHMLRQLEGLDLGGTFLSAMPNAGYPTVLGRRTVYQ
GTPDYFAQRLEQLVQAGAAIVGGCCGTTPEHIARMTATLARSSIRRPGTLPGQPHPHRAA
PKSPLWDKLDSGKRVVAVELDPPVDDDIAPFLEGVRILRDAGVDAVTIADCPVGRPRADS
SILACKVRRELGVEPLPHLTCRDRNLNATKALLLGLSMEGVHNVLLVTGDPIPSTDRDEV
KSVFNFNSRKLARYTSSLNEGTLNTPFRIFGALNLNARNFDVQLRLAREKEECGVSGFLT
QPVLSPEALENLKRARAALKGKILGGVFPVVSYKNALFLNNEVSGIRVSDEIIALYEGKS
REEGEDLAVQISTRVAREIAPYTDGLYLMTPFRRVHLITRILRSIQQ
>A0A7K2N8C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5468|TrEMBL
MALGTPSTRTDRAVTIRELLASGERSYSFEFAAPKTEKGERTLWNAIRRIEAVNPTFVSV
TYGAGGSSREGTVRATDRIVSDTTLTPCAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGEWVPHPRGLRYAAELVELIKESGDFCVGVAAFTEMHPRSTDVETDTRHFVA
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFSQLGNAPF
PPALAERILAVQDDPAAVRAIGIEFATEMCRKLMAEEIPGLHFITLNHSTASLEIYENLG
LHRRP
>A0A7G6SLT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium huakuii|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTIGRILNETSLTPAAHMTCVDAARHQVDAVIQEFVDMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A150NGW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYL
TKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATDLIEFIKEQAHHFDIVGAC
YPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGI
MPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVA
GVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3B0ZQH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKSQQIYPLAFSFECFPAKTETGKEKLLKTCHQLASVNPCFFSVTYGAGGSTREHTLAAV
DDINAATSIEVAPHIAGIGASKGEMSSLLEHYKARGIRHIIVLRGDTPSGLRDFGDFNDA
IALINFIREQYDDYFFIEIAAYPETHPLATSAQTDLANLQQKFERGADAALTQYFYSPDT
FFRFIDSCEKLAIDQPIVPGIMPITNYHQLARFSDRCGVQIPRWIRQRLEGYGDDLASIT
AFGEEVVTRLCEQLLAGGAAGLHFYTMNNAAPSLAVWKNLNLSNDKSSRSRR
>A0A1G7UJ68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterium luteolum|TrEMBL
MGPIRGENRPSRQPDAVRPDIKVSFEFFPPKTDAMEERFWDSLSRLAPLGPRFVSVTYGA
GGSTRERTLRMVSRITNETGVPAAAHLTCVGATRDEVDAVVRGYAEAGVNRIVALRGDPP
EGVGQPFTPHPDGYRNAADLVAGIRKLGDFDISVAAYPEKHPQSPDWDAEIDNLKRKLDA
GADRAITQMFFENADYWRFVERARKAGVEAPIVPGVQPIHSFKQIAGFAGRCGASIPQWL
ADRFEGLEDDPETHALVAAAVAAEQVTELLDSGVTEFHFYTLNRSNLVLALARLLGIRP
>A0A081QB62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKNMVAETIADLDKVGVQKILALRGDIIPDVEPQKDFQYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQVLRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A4D6Y983|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MYTLNNYIFENNIFHTTSKIHVSFEFFPPKLNTIKNSSFFYAIKKLSTLKPDFISITCTS
RNESYNHTYKTVLEIQKKINIKIVPHMIYSNTTTEKIKRIANKYWHHGINSIVALRGDYI
NKPNNSSLKYASNLVILLKQIANFDIFVAAYPEVHPEAYNAQSDLIYLKNKIDLGANLAI
TQFFFEVEHYLRFRDRCAAIGIHVDIIPGILPIIDFQQLKKFASMTNVYIPKWIHTMFEG
INSNDQNISKMIGLSISINIIQQLCKEGVRHFHFYTLNQYDITYTLCHMLGLRKYNNL
>A0A3B0U5S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MYKVRLWCIRRSRLLETVYLVTKPAIMFGLSAAKKVFGRFLDRPVIVVERSIKGFLFDCQ
MCGDCVLSKTGMSCPMNCPKNIRNGPCGGVREDNMCEVKPDMLCVWVAAWDGASRMKGGG
GIQNLQPALDHRGKGTSSWLKLARENAGDE
>A0A081PND2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVSGVHLYTMNNAETAKYIHQATHALFNHQSLG
>E6ZVM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporisorium reilianum (strain SRZ2)|TrEMBL
MASPSAAAPAAGASSSDPAHITSKIHAASSRDAPFWSFEFFPPKTTQGLANLYNRIARMR
ANLDPSWIHVTWGAGGTTGGKSLELAGRIQKGKLDPAVEVVQNEVKQIGSGAQQHIENVQ
GGEPWEQAGPDACDVCLHLTCTNVEKSSLDQTLETAKRLGIKNILALRGDPPRGEEYWVA
ADERFQHATDLVRYIRHNHGDFFCIGVAGYPEGHADYVDRDVQRDLRYLKEKQDAGAQYI
VTQLFYDVDQFLSWYKDCRDIGITIPILPGIMPVQNYSSFRRMTNLCKVQVPQLILDALE
PIKSDDAAVKEYGVSLSIHMVGRIFLESDIRGFHLCSLNLEKSIERILEGLGWKTDLGAQ
PEGDARLRGIPAHLHLEATKNQMLSDRTGANTPKDFKVTTQEALARTLARTSSSYQVPET
STWDEFPNGRYGDSRSPAFGEMDGYGVSLKVPPQDALRIWGHPVTLVDISKIFASYLEEK
ISCIPWCDAPLMNETLQIRDHLLSLNRLAEGASQSGKGWWSVGSQPAVDGAPSTDPTFGF
GPPGGFIFQKSFVELFMSTADKDKLVARIDALGTNAQITYFAGNARGDFQSNLGDGEANT
VTWAVFPGKEIVQSTIIERESFEAWRDEAFEIWGEWSLLFPKQSASRKLIEQIKDGRWLV
TVVHHDYKQTEALWHFLAE
>A0A376GFR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Empedobacter falsenii|TrEMBL
MKVTEHIERANGKPLFSVEILPPLKGQDVNATFKTLDPLVELNPAFIDVTYHRQEYIYKQ
KENGLLKRYQVRKRPGTVAICAAIQNHYKIDAIPHLICGGFTKEDTEDALIDLNFLGIDN
LLVLRGDPIKSEKSFVPEVGGHAHASELIEQITALNTGNYLDDELQESHAMDFCIGVAGY
PEKHFESPNLAMDLYYLKKKVELGADYIVTQMFFDNQKYFDFVKKCREMDINIPIIPGIK
PLTTFNQLTSIPQNFYLDLPEALAMEVLKSKDKERIKEIGIEWCIQQCKELIDFGVPGLH
FYTMSNSINTKRIAEAVY
>A0A6A1RXQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter guillouiae|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKLVHQELQLLNPEFFSITYGAGGSTRERTLAAIADFN
GKGTPVAPHLSCIGDDKVRIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADNFDADIQHFAEKVKAGANAAITQFFFNPDAYFYFV
ERIQKQGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTVSIKAFGHE
VVIKLCERLIAGGAPSLHFYSMNHTEPNRQLVLDLGLA
>A0A1J4X8Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium CG1_02_48_14|TrEMBL
MKVIEYLEKATETLISFEIIPPMRGRSAQEVYTILDQLIEFEPPFIDVTSHAADAYYVEQ
KDGSFKRYIKRKRPGTLGLCAGIKYRYKIEAVPHLLCRGFTREETEDMLIELNYLGIENL
LAVRGDDPNYQKAINPDRSKNNYAIDLVRQVADMNRGRFQDDILDSAQTDFCIGVGGYPE
KHEESPNLEADIRHLKEKIDAGAHYAVTQMFFDNQYFFDFEKKCRDAGITVPIIPGLKLL
TKPYQMKSLPSNFHVNIPDTLVAAMTAADSETEAQQIGVEYLKKQAGELINAGVSCLHFY
VMNDVHLVKEVVRSLK
>A0A3B1A024|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MQTQKKHPQNISCEFFPPKTVQGKEKLGNTINELKKLDLSYISVTFGAGGSTQEGTLETI
LAVKSEGIDAAPHLSCIGSSRENIRSILDQYKSNGIRRIVALRGDMPSGMREAGEFRYAN
ELVEFIRDEYADDFYLEVAAYPEFHPQAESAKDDLLNFKRKVDAGADAAITQYFYNIDAY
LRFVDDCEKMGIEIPITPGIMPITNYTQLARFSDSCGTEIPRWLRRRLAGFGDDIESLKA
YGLEVTSELCYSLLKQGAPGLHFYTMNRSVSTLAICKNLGVISQASGQDHN
>A0A151ZAC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tieghemostelium lacteum|TrEMBL
MTSVKIIDKINGFKEQKKPFYSFEYFPPKTNEGVQNLYDRLGRMLLFEPLFADITWGAGG
STSTLTLEIAEKAQNVCGLETMMHLTCTNMPVSEIIYALEKAKATGIRNILALRGDPPRG
EEWKKIEGGFGYASDLVRFIREKYGDYFGIAVAGYPEGHADCVSKETDIQYLKAKIDAGA
DFVITQLFYDVDIFVDFVKKCREAGITVPIVPGLMPIQTYQGFKRMTTLSKTIVPQYIND
NLEPIKDNDEEVKKYGVKLCIEMCNRLLDAGVDGLHFYTLNLERSVRKVLKGLSLVRPDQ
LSPYLPWAQSAAGKRLKEEVRPIFWQNRPRSYIARTGSWDEFPNGRWGDYRSPAFGDLSD
YHLGWAKAEDTTSVYGPNPQSEQDVFEVFASYCSGKIKKLPWNDAPLSLESDPIKEQLVF
LNRNGFLTINSQPALNGVPSTHKIHGWGGKNGFIFQKAYVEFFTSPETTQKLIDYIKKCP
MMTYHAVNKAGDSKTNTKGTNAVTWGIFPGKEILQPTVVDQTSFMVWKDEAFALWNTQWS
STYPEGSESRKVLDSMIDNYYLINIVDNNFISGNIFQPFTDLVNNLSSPVLTSSTNGTTP
SLNGSVNGLTTSVSNLNVQ
>A0A081PZW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDEVGVQKILALRGDIIPGVEPQKDFRFATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A8H8JF72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceratobasidium sp. AG-Ba|TrEMBL
MKVTQKIERAEKDGRIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFVDITWNAGGRTS
DLTAELVKTCQGVIGVETCMHLTCTNMPQEKVDIALKEAKAAGCRNILALRGDPPSGQEE
WTTVQGGFQHGIDLVRHIRKEYGDYFDIAVAGFPQTITLPEAEAAQEMQWLKEKCDAGVN
FIFTQMFYDADVFIRWVKAARAAGITIPIVPGINPIQTWNGFIRATTLSKTEIPQDLMDA
LEPHKNNDEKVRELGTKIVAEMCRKILSADIGIKGLHFYTMNLEKGTKMLLEELNFVPRV
ETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTPEEGLKIWGTPTTVEDVKNLFAAFCTNQLKALPWSDQPPSTEMKVIGQQLA
RINELGYLTINSQPAVNGAKSDDKVFGWGPKNGYVYQKAYLEFFVSPDQLKTLIKRIERD
PNVTYYAINKQGDLKTNSTSEGPTAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGCQ
WAQIYEPGSPSRKLIKNMMDEYFLVNLVHNDFQDREAIFRPFFADAGLKLNGEEPVAKLN
GEIAGLKLNGDSHPKAIKA
>A0A7X3A8T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. NEAU-GSW1|TrEMBL
MSNATEKLSLKEALGQRILTGDGAMGTYLYQMGFPVGVSYEEFNLLRPDVIENVHRRYYE
AGARVIETNTFSANLEKLAIYGLDAEMEAINRAGVRIARAAAGSDAYVVGAVGSIRAGKL
KNIRTAKVSEAYERQMEAMLSEGVDGLLLETFYDFDEMMLALRIARKLTPDVPVICQFAA
EDVGRTQDGTALKDAFDQLQLVGADVVGFNCRSGPNGILRAIDAIDGPVALPLSVFPNAG
IPDYVDGKYSYSAGPDYFAETARRFADRGARIIGGCCGTTPEHVKAMAEALKDYVPAVQN
GQAVAVAASAAPKSETITVAGKPEVAVVSTVADRGANDAANGQPVDPNIVDLVKQRHTVI
VELDPPRDLDIRKFMDGAAALKACGADAITMADNSLAVTRMSNLALGALVQEKIGLRPLV
HIACRDRNLIGTQSHMMGLDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIKMIKQ
LNEGIAFSGKPLKQKAKFVVGAAFNPNVKHLDKAVQRLERKIKSGADYIMTQPVYDPALI
EQIAVATKHLDVPVFIGIMPLASGRNAEYLHNEVPGIQLSDSVRQRMAGLEGEAGRAEGV
RISQELLDVAIKHFKGIYFMTPFMFYDMAVQLTEYVWAKTGVGK
>A0A143PMG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteitalea pratensis|TrEMBL
MNQSFLDALRARVLICDGAMGTQLYARGVFLNRAFEDLNLTEADMVVGVHQAYLRAGAEI
IETNTFGANRLKLASFGLAEKVHAINLAGARIARHAARDAAWVAGSIGPLGVRVEPWGKT
GLDEAQTIFAEQAAGLAEGGVDLFVLETFRDVNEIGAAIHAIRSVSDRPIVAMLTTAEDG
NTLDGTPVEQFGPQLVEFGADVLGVNCSVGPAAMLDTIERLAKAVPGALLAAMPNAGKPR
DVDGRNLYLCSPDYMASYARRFAGAGVRLIGGCCGTTPDHVKQIAHAVHALSPAVPAASA
VADVAPDAPPRVSPVPVEAKSQLSNALRRGRFVTGIELVPPAGFGHDRIVEQAREARING
LDVVLVSDGSGSRARMSALASAVTVEQVAGAETILQYCCRDHSLHAMQADLLGAHALGLR
NLLLVTGRPLRHSEYPDATAVFDVDSIGLTNVAARFNRGEDVGGQPIGQPTAFHVGVAAN
PTAVMPDRELSRYRYKVEAGAEFVVMGPIYDVDALRQFLEDTAGQRVPVIAVVRAFETAR
QAEQLANEEPGVSVPESLVQRMAEAERVGHVAEEALAIARELVVAIRPLVAGIIVAGAGG
RVGAALDILGALTNASSIRTDDAPAGAVRRQVAVS
>Q748M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)|TrEMBL
MTFLERLHDEVLIGDGAIGTMLYAKGVSLDANVEHLNLVRPSLVLELHREYLAAGARVIE
TNTFGANWTRLAAIGLEKKEREINLRGAQLAREAAQGTDAFVAGSVGPLVRMKGDEQELS
AQETVDIFRRQTHALAEGEVDLLILETFTDLAQMRHALTAARETGLPVVANMAFLENGRL
AGGIEVERVAVELTAAGACVVGANCGAGPLEILGTIQRMGRVTDLPLAAYPNSGFPEYVN
GRHVYRTTPDYFADRAVEMVGAGAALVGGCCGTTPEHVRCLAQRLAGLRPAARTVAVSAL
PKDERRPESREYAGFLARWGREPIVTVELDPPKGLDCAKIIEGSRALREAGADAINIAEN
PLARIRMGNIALGSLIQREAGIDVIVHVTCRDRNLLGLQSDLMGASLLGIRHVLAVTGDP
ARIGEQAGATSVYDLNSFGLIKLLADLNAGVNALGSPIGGGTGFVIGAAFNPNSARMEVQ
VERLARKVANGARFVQTQPLYDVARLEEMAERTAHLGIPILPGILPLVSERNCEFLHNEV
PGIVIPEEIRHRMRGKEKEDGVREGLAIAREFIDAVRDRVGGFYLIPPFGKYGIAVELTR
YIKGT
>R7LL90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:729|TrEMBL
MKLREIYNNNKTVISFEVFPQKDDEAKLLEEITILNKYNPAFISLTCGAGGKENKSFELL
KDIQNLGINVMPHFTCITSSKKSVEEGLKEIENIGIENILALRGDIPENTELRHYDFNYA
NELVNYIKAKTNLSIGVAGYPEGHVESPDIKSDIINLKKKVEAGADAIFTQLFFDNNKFF
EYVQLVRNEGINIPIIAGIMPIKSYKQIVKMTSLARVAIPENLQTKINKYKEDSKSMTEL
GIEYASKQCEELINNNVMGLHFFTLNKSYSTSQILNNIL
>A0A140NN52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia stuartii (strain MRSN 2154)|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRTEEMEQTLWKSIDRLKKPQTKICLCYL
WRKLR
>A0A1F3IIH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWF2_33_16|TrEMBL
MKVIDKIKNSKKPLFTFELLPPLKGHTIQEIYNTIDPLIEFNPAYINITYHQQEVIYKTR
PDGLMEKRVIRKRPGTVAIAAAIQNKYKITVVPHMICGGFTKEETEDALIDFQFLGIDNL
LALRGDPPKGARQFIAEPGGHSHSSELIEQIMNLNKGIYLNEDLVDAMPTDFSVGIAGYP
EKHVEAPNLESDLEYLKLKVDKGADYIVTQLFYDNQTFYSFVDKCRKIGIDVPIIPGIKP
VSTLNDISLLPQTFHIDLPNDLVQEIKKCKSNKEVRVVGVEWAIEQSKQLIKYGAPGIHY
YTLDQSDNVKKIAQAIF
>A0A1G6C3E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. INlla16|TrEMBL
MGSIKDLYGKGKTVLSCEIYPPKKEDEFNNIYTKLEQLSEIKPDFVSVTYGAGGSNAGKA
VEIADYAKNKAGLEVVSHITSVGFSKEKLEEGLNRFKDIGIENILVLRGDRPKLMTDEQF
NTRDFLHASDMAEYIKGKGMDFTLLGACYPHKHPEAKSEEEDINNTKTKVDKGCDVLISQ
LFFENDYFYRLIDKLHDLGVKAPISAGIMPITSAKQLGTTVTLSGTTVPEELSSIISKYG
DNPEEMKKYGIDYAIKQALELKNRGVDGIHFYIMNKPDLAKILMDAVR
>A0A3M3SPD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. phaseolicola|TrEMBL
MSQERRFSFEFFPTKTDAGHKKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A3D6BSI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomarina gelatinilytica|TrEMBL
MKVTEHIKNANGNTLFSFEILPPLKGQNVQSIFDNIDPLMEFKPPFIDVTYHREEYVYKE
LENGLLQKKVVKKRPGTVGICAAIQNKYRVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKTETYFKAEKEGHHYASELVTQISDLNKGTYLDEDLLNSSCTNFCVGVAAY
PEKHMEAPSLDSDIHFLKKKIKNGAQYIVTQMFFDNNRYFEFVEKCRREGITVPIIPGLK
PIATKKQLNLIPHRFHVDLPEDLILEVVKCQNNEQVRQLGIEWCVQQSKELQKAGIPVLH
YYSMGKSDNIKAIASQVF
>B4LC84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila virilis|TrEMBL
MCVNVTRCRATAAIWNVAALAQKRCYQFQLSERTQSVRSAIDVDLAMHSVDTVGAQHFGT
NLSDVPPVAPIIEPCFQFTPEQKASAGQQPYISDLVTSKTARGEFFYGIEITGQSKGKPT
CVDFNGFLPVLPTFISIVWLPQYWNVMPIERVETLQLIRNLETHIPAMPHLSLFRQTKER
IDEFLALNFRNMLAVRGDKTHEDQVYRYSHQLVEHARRVRGVNISIAVAGHPQGYAGGPQ
GLAESIEMLKKKIDNGADFIITQLCYSPETIVEFLRGARNAGIQTPIMVGVVVPDSFKSY
ALIEMISKISLPAEARAEVEKYQNDDAKVKSYFVQLALRTIQQVLDANLGVHGIQFYTLN
RFGSVQDVLCELRKLGILKETPPKDACGDA
>A0A0R2RGL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 6 bacterium BACL9 MAG-120507-bin52|TrEMBL
MANLLEALGSRIVVGDGAVAAYLYAEGVPLGRSFEGFNLTEPDRVSAAHRAYLEAGSEVI
ATNSFAAGRFSLQRHGLEDKVNEINWKAAKLALGEVGKSGAWVVGCIGPCGIPQAEWGAA
HGVEALFRQQAGGLLDGGVHAILLQSFSDPKELTVAMEAVRELHHLPIFALLAAGREGTL
PGGKHWEESTRQLREAGAEVIGVAPAFGPSACEGLMKRISSGPGKLLAAYPDAGQPEFFE
GRYLYANHPQYFAQRMAELPALGVNLLGGGSGVSPAHIRALKAKVGGLKPATQVRAAVEP
KREAIQISSGAGEGKKEESILDRLKKERIAVVELDSPRGLDMGPFLKAAEELVKAGATAL
TLADNSLAILRVANTAAATLLREKFGTTSLIHLACRDKNLIGLQSELMGLAALGHRHVLA
LTGDPSKFGDHPGATSVYDVNSLGLIDLIRQLNEGRNSAGREVGKGAEFVIGVAFSPNSK
NFDAQVKKLERKMEKGAHFVMTQPVYELEMIRKMKDALGPLGIPVLVGVMPVVSARNAEF
LHHEVPGISIPDRVREKIRSLPEGPAQAEYGREVAAELAREVAQHFRGIYLITPMVRSGM
TAPIVQEFLKTK
>A0A357ZDD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriia bacterium|TrEMBL
MSNRFREALESGEFVVTCELIPGRGANEPAQQKEYDAAVSIYNTGRVHAISITDNPGGNP
AIAADAFAGELEEQGIPTLVHFTCKDKSRNQMQAQLYSMQRRGLQNVLVMTGDYIYSGWE
GRSRPVFDLDPVTATQMINDMNQGLVVKGPRGESREEPADFFPGACVSPFKWTEAETVTQ
YLKMEKKMLAGANFIISQLGYDARKMEELMIYVREKGYDVPMIANVYIISAGTARFMKGG
NIPGGYMSDEFLEILTEEAKAEDKGKAARLLRAAKMVAISRGLGYAGVHIGGLNLTAEMF
NEILDTADRVQDRWREWVEEIHYGQEDGFYLYEPELDADGKKTGFNTTNPAPKNDSYEGK
KHLMKGYGLSRFFHHLMLTKNKGLYGMLKGRMEGLDKKKGVNREHGLEHTGKAMIYGCMD
CGDCGLEATVYTCPMTGCPKSQRNGPCGGSADGWCEVYPNERYCIHVKAYLRLKKYNELE
KLDSFITPPNNWDYYHTSAWSNYTHDRDNCANRQYLPAPDRRPQAARDKRTGKVDEKKES
>E1VQZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium HdN1|TrEMBL
MDTQKKHKPRFSFEFFPPKTEVGAQKLQVVCEKLAAVNPSFFSVTYGAGGSTRDRTFATV
QDVRKVSGICTAPHLSCVGDNRDELVALIKRYQSEGINRIVALRGDLPSGMGAADGDLKY
ASDLVRLIREETGDHFHIEVAAYPEKHPQAPTLASDLQAFKAKVDAGADSAITQYFYNVD
AYRFFVDRCEKLGLDIPIIVGVMPIINYENLLRFSSSCGAEIPRWIRMQMESFHGDATSI
AQLGEEIVTRFCEQLLAVGAPGIHFYTMNQAEPTLAIWNNLGIGKR
>L8TRW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter nitrophenolicus|TrEMBL
MSPPSLIETHPNLSDAAPVALSYELFPPRSPAAAETLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIIGQLLDTGVRGILALRGDLPAD
GQVTDGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPARHPESPSEEHDVEVLLA
KQRSGADFAITQVFFHADQYADLLTRARRAGVTIPIIPGVMPLTSLRRLNRLGELTGVEP
APELTAKLAAADTDLERLHIGVDATVDLSNAALDAGAPGIHIYTFNEHQSALEVLDKLAL
PRRGRAGVRPASTVRPPARRLTQHTRRPRSLTPPWSGSSALPSFPLCLR
>A0A013SPJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 826659|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A2L2JDV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. SGAir0187|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A437J5N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium algorifonticola|TrEMBL
MTLSLLQMEEARRALDVPLFADLSGDAQVSFEFFPPKTEKMAAQLWASVETLTPLAPRFV
SVTYGAGGSTRERTHATVARIVRETGLSAAAHLTCVGASRDEIAQVADAYWQAGVRHIVA
LRGDPPEAGQVFVPHPHGYASAADLVKGLKALHPFDISVAAYPETHPDALSAQSDLDNLK
RKMDAGASRAISQFFFSADAYFRFRDAATAAGIDAEIVPGILPVSNVEQTRKFAAMCGAT
IPPWMDRLFEGLDDHPATRQLVAATIAAELCRKLYAGGVRHFHFYTLNRAELSYAICHLL
GLRPGAAAPVKELVA
>A0A847KNE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter sp|TrEMBL
MNPLLKSWLSEESIEKTSQHNVVAPILSFEFIPPRTEAMERRLWQCIQRLAPLSPRFVSV
TYGAGGSTQASTHSTVLRIKQKTDLAPAAHLTCIGATREDIDTLAQNYWDNGIRHIVALR
GDPPAGSDYTPHPDGYAYASDLITGLRRIADFEISVAAYPETHPTALNASTDLDNLKRKF
DAGATRAITQYFFDTSSCLRFLDRCRAAGITAPIIPGIMPISNYEQIARFSALCGVSVPA
WLTHLFEETSKNPELHRIVACVVAVEQIRTLQANGINEFHFSTLNRPDLTCAIAHILGIR
PIGQEKISHTNKKTKDDSTSLMLRTMFE
>A0A8J3N392|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reticulibacter mediterranei|TrEMBL
MQTNSPFLERLARGPILCDGGMGTQLYARGISYERCFEQLNLTEPELIKAIHLDYVAAGA
EIIETNTFGANRYRLAEHGLETQVQKINRAGARIARDVREMCDAQIFIAGNIGPLGSPLA
PLGTIQPEDARAAFGEQAEALLQAGVDLFILETISNLDEMREALMAVRSLTELPVVALMT
FDEDSAIASGEDALTVAHTLHKLGANVVGVNCALGPSSTYDVVTGMLSDPNNPFIVAAQP
NAGLPRRVGNRFIYVSTPDYFADYARRFLDAGVRMIGGCCGTTPQHIAAMHKVLVEFAPN
LATSAPSVPAPRVESVRERPTIPNEGGSHPANAQYPTKLARMLGKNKFVVSTEMRPPRSV
KFSRFLENASYLRNIGVDFINIPDNAMARVRMNNTTAARLIQDRIGIETIVHFTPRDRNL
MAVQSDLIGTYASNIHNVLAVTGDPPSHGDFPNATGIWDVDSIGLIAILHNLNQGFDGTG
RQLAAASNFFIGCAAVPTAPDVDLDIERLHRKIEAGANFIMTQPLYDPAILFDYLERYKQ
RYGPLPIPVLAGLQPLHSYQQAEKFHNEVPGIVIPESVRTRLRQAGEAGAATGVDIIKEL
FDTIYPHIQGVYLMPLDRYTLVGELLPYIQERIQTAQGIDSSND
>A0A0M0GEY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina globispora|TrEMBL
MSFLDKLKNEIIIADGAMGTLLYSYGTDSCFEELNLSQSEQIQHIHEAYIGAGAKLIQTN
TYAANYLKLQRYGLEDSVKEINSAAARIAKKAANGSTYVAGTIGGIRGFKPNMITLEEIK
RSFREQLYCLLLEDVDGILLETYYDFEELETVLAIARRETDLPIIAQVSLQEAGVLQNQT
PIADALTKLESIGADLVGINCRLGPHHMLKTLESVPLPKHAYLSAYPNASIPAYIDGKFH
YEGDPDYFRQSAIGFRNQGVRLLGGCCGTTPEHIKAFAEAIKGLPPVKEKEVKEINKVIV
SDKPSSSRELPPLQDIVMERPSVIVELDPPRKLDTRRFFDGARALKEAGIDSITLADNSL
ASPRVCNSALGYLVKQQTGLRPLVHVTCRDRNIIGLQSHLMGLHALGLNDILAVTGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSFSGKDLGRKAAFSVAGAFNPNVRSLEKAVG
RLEKKIEHGADYFISQPVFSEEKLLEVHEAVKDLKAPVYIGLMPLTGSRNAEFLHNEVPG
IKIADSIRNRMAVLKDDPAKAGLEGIAIAKSLIDAAAELFNGIYLITPFMRYEMTVELSN
YARMTTERLSRRKQHV
>A0A8E0IA28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei subsp. paracasei Lpp22|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPHACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFPGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A5Q2P1M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. B01|TrEMBL
MSSTLKDKLLRKESGILTYGMTPPKSSHPPEKIREIADKQIERLRGAGIDGLVLYDVQDE
AERTDENRPFPFLKALDPTEYYEQYLKQELGVPAIIYHCVACEGPDKLASWILRGRDEQR
YSVFVGASSSRQQVQIRLPEAYRMSGILNERLLPGGVVIPERHRSKGDEHERARAKQEAG
CGFFVSQATFDVEASKSFLSDYYYSSRESGAEMAPILFNLAPCGSAKTLEFMKWLGISIP
KWLENELIHSVDILDKSVQLSRQVFRELYRFGLEKGIPIGCSVESVSTRKVEIEASIQLL
RDIREDMSRIGAELAPSIPSHN
>S6W3D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. actinidiae ICMP 18807|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A363RCF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp. JNW|TrEMBL
MTFPISFEFFPPKTPEGADKLRVVRQALYARKPQFCSVTYGAGGSTQEGTFGVVKAILDE
GVDAASHFSCVGATKQTVRAQLQQLKDMGVKRLVALRGDLPSGYGLGGEFHYASDLVTFI
RDEFGQDFHIEVAAYPEMHPQARNPEADLQAFLAKVKAGADSAITQYFFNADAFCRFQED
LQKRGVDLPVIPGIMPITGSTQLMRFSDACGAEIPRWIRLRLQGYGDDVASIRAFGLDVV
TQMCEDLRRRGAVGLHFYTMNQSAATLAICDRLGL
>A0A084EH08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaesserella parasuis|TrEMBL
MLYLKQKIDAGASRAITQFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAK
ITNVKIPSWMAKMYQGLDDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRSELSYA
ICHTLGVRPE
>A0A2G5MXZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 2822-17|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIQRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A6N9NGF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiluteibacter ferrifornacis|TrEMBL
MKVSELLKNTKKTLFSFEILPPLKGKSIQSIYDGIDPLIEFNPAFINVTYHREEFIYKKR
EKGYLEKFSIKKRPGTVGICAAISNKYQTPSVAHLICGGFTKEETENALIDLNFLGVNNV
LALRGDPIKTEQYFVPEEGGNEYAVDLVKQIINLNNGNYIEENIENAAPTNFCIGVSGYP
EKHSEAPNMKEDIIRLKAKIDAGAEYIVTQMFFDNQKFFNFVNLCRENGIEVPIVPGIKP
IATKRQLQILPKLFHIDLPEELTDLVEACTTTEEVKTVGEKWALKQCKELIDYGVPCIHF
YTMGKSNAVRNIAKEIF
>A0A381NNQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MNTSFEFFPPKTEKGKESIVDLTRKLSNFSPEYFSVTYGAGGSTRKGTLETCVSIMSLGQ
KAYPHLSGIGASKASIKEILNDYKEQGLTKIVTLRGDLPSGIGGLGDFPYALDLIKFIKK
EEENFSIEISAYPEVHPDAESENADFENFLNKVSAGADGAITQFFFEEDSYFKFMDKCEK
EQISIPVVPGILPIHDSEALIRMAKNCQAQIPLWLREGMEKFSNNEDLLGYGVEVITKLC
EKLLHFGAPGIHFYTVNREEPTSSIVKNLEIN
>A0A829S147|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 225588|TrEMBL
MTLADRVHSDHDIAPLEASKSYPDIIDKVLHFSGKARDIQDFELFLEQAKSANIQNLLLL
TGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLH
KKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQQILACVMPLTLGRANYMVKHKVAGI
VITPHMLKVLAEEKQAGHTDRVYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIE
QYRHLNLKALEELWSSLWQVKTGKEFIPEITRFSRQPTSKQLIKYRQLHVMHEAMFGSKI
AKGVGRFIFKASFWENSLVAKVLIKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGL
ANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQTEILKEKLIPTVPLETRGTSSWKNWY
LATEA
>A0A381PMU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MALAKSDSVRLIRDIYADRQSVDRPVISIEFFTPKTSKGDQVLCESTLPALIRLRPDYCS
VTYGAGGSTKSKTLSVTDMIQRQFGLTAMAHLTCVESSKNDIGAVLDEAKELGIRNILAL
RGDPPGGSGEFVKADDGFEYSYELVRFIKANGDFCVGTAGFPEGHIACTEGKHVDWGYLK
NKVDCGADFVLTQLFFDNSDFLRFRDYIVRKLGVTVPICPGVLPILSTKQISKFTKLCGA
RIPKPLAARLESLGDDDEATTAFGIEYATKQCEELIREGVVGLHMYSLNKAHSTSAIIKN
LGLS
>A0A2E3SV03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MKFASPKKDTKVSFEFFPPRTVAMKEQLWKSIQRLRPLNPQFVSVTYGAGGSTRDRTHET
LKKIRKETDLKPAAHLTCVGSSREDINKIANTYWEEKICHLVALRGDSPDMGSYAPHPEG
YEHASDLVEGLMKIADFEITVAVFPEIHPESNNLKEDLDNLKRKIDAGAQRAISQFFFDP
NVFLDFLNKVRTSGIKIPIIPGILPVTNCEKVIEFSKKSGTSVPGWMKKIFQGLDQDPVS
RQLVAATIAAEQCKALQDNGINEFHFYTLNRADLSYAICHILGLRINSR
>A0A6H9UUJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces luteolifulvus|TrEMBL
MADRRFELICEVEPPTRPDLTRVRHQIGVLSPIADSFLIPDNHIGRATVSSVAVAHEVQA
MGARSIACLNSRDRNLLGFQRDLLTAAAYGVERFLFVHGDKPSAGGRTSELTVRAMIEQA
RAAEEDPAFGGCGPFRAGVTSGLRPLPGWKSAADFVFVQVSYSLESLLRWRDSVSLSVPV
YAGVMVLASAGMARNLAAKIPDIDIPEQLVIDVQRDRDAGVAAACEQVLAIRDSGAFDGV
HLVPVSRYRQVAALLEREL
>D6E5X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] rectale DSM 17629|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNQYNVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>A0A7W1JKU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MVPPATRPVRPRLPDVFASGRRSFSFEFFPPRDDAGERRLWTTIRQLEPLRPTFVSVTYG
AGGSTRDRTVRITGGIATDTTLRPVGHLTCVGHVVDELRRVVGQYADAGVRDLLALRGDP
AGGPGTPWVSHPGGIDRAVHLVELVRSLGDFTVGVAAFPEKHPEAADLESDAAILVAKAR
AGADYAVTQLFFRPTDYLELVERVRALRCDIPIVPGIMPITNLAQVQRMVRLSGSAVPDA
VVERLAPYADNPASVRAAGVELAIELCGRLLSEGAPGLHYYTLNTSTATREIHAALNVPV
>A0A838K8Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MTPEPDDPAGGREQRLSAVFASGRRSFSFEFFPPKDDAGERQLWTTIRQLEPLEPTFVSV
TYGAGGSTRDRTVRITERIAEETTLRPVAHLTCVGHDIAELRGVVGQYADAGVRDVLALR
GDPSEGPGSPWQPHPGGLDRAVQLVSLVKSLGDFDVGVAAFPEKHPEAADLEADAQFLVD
KAQAGADYAVTQLFFRAEDYLRLVDRVRVLGCELPIVPGIMPITSLTQVQRFATLSGSQV
PPEVVDRLSPYADDPRALRSAGVELAIEMCDRLLGQGAPGLHYYTLNRSTATREIHAGLG
VHA
>A0A1H3MT83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tindallia californiensis|TrEMBL
MLKEKIINRKSGILLYGLTPPKNNQPENKLFEISKRQIDRIEKMDIDGLILYDIQDEQER
CLEERPFPYMKTVDPESYSDKYLQALKMPKIVYKCVGKHSVEDLERWVNNENEETRISVF
VGAATGKQPVSIHLAEAYEMARAKGANFLLGGVAIPERHINKKNEHSRVIDKEDKGCCFF
VSQAVYNIEASKNFLSDYYYRCLEEEKSMSPMIFTLTPCGSVKTLKFMKWLGVSIPGWME
NDLIYSQDTLNQSLQLSKNVFEELLEFAAKKNIPIGCNIESVSIKKEEIDASITLLEDVR
KLMG
>A0A4Q2XD69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MHIHEILTGDEPKFSFEFFPPKTREGAETLFRHISELQLCAPAFVSVTYGAGGTTREATH
ELVLRVQRETSLPTTPHLTCVGHTEGEISQILERYAEAGVSNILALRGDPPKTGTTKAGD
FPYAADLVSFIRRFSETHGHRFGIGVAGFPEGHPATPNRVLEMEHLKAKIDAGADYICTQ
LFFDNHDFLDFRDRCELAGIEVPVLAGIMPVTSMAGLRRMAELAAGARFPARLLKALARA
NGNEDAIRRIGIHHATTQCADLLDQGVKGIHFYTLNQSTATLEIFNHLGLRDSVAFCA
>A0A3M0W2X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetothyriales sp. CBS 134920|TrEMBL
MADGHITTLISALPPDQPFFSLEFFPPKTQAGFTNLRSRLSRMATALRPLFVSVTWGAGG
STASKSIELAEVCQCQLGLPTVLHLTCTNMKKKTIDEALAACKSRGIRNILALRGDPPRA
DDYRESDDDDDNDVDNAENHKFAWAVDLIRYIRQKHGDYFCIGCAGYPEGFPPETQALHP
PKQSPEHDLPYLADKVEAGAQFVVCQFTYDFESYARYESLVREYTHHNGKKVLQNIPMLP
GIMPIQNYSMLKRICKLTHVALPADLVAKLEKVKHDDDAVKNIGVQVLADLVNGIRDLPS
HNLDRGFHFYTLNLEKSCVSILDQAKLIPPLREATPPESSSDSEVLTDGPASTHQQQHQH
FSRRRASSINAQAHNRVIISSPTTDTNTNTDPSTALPKSQHEAPARGAGIPASDPTREQE
LLISKGHGSLGREATWDDFPNGRWGPAHSPAYGEIDGYGPSLKVGPLTARKLWGHPKSAD
DITNLFQRHVLGQLEAIPWSDEIDGDEAGAPGAGVLRAETRVIRDELLALIGKKHYWTLA
SQPAVDGIRSDDPTFGWGPQRDGFVFQKPFVEFFCLEDEWANNLKPRLQRFPPEKVSWMK
VDASGSYESSSEISSTFGPVSSKTSRDNARGNTVTWGVFPGKEIVTPTFIESESFRAWSD
EAFAIWAEWRRCFPRGSDEEKFLERMRQNSVLVNVVGHDYIGGASGGGKKLWEILLAD
>F9RDP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. (strain N418)|TrEMBL
MGYTHASHIDALNQNVAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKNLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLIAAPHLTCIDASRQELVQIADDYWANGIESIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFNQASRFAAQNHVKVPGWMAKQFE
GLDDDPTTRQLVGASQALDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A1Y5ES50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cycloclasticus sp. 46_120_T64|TrEMBL
MALESNQPISFEFFPPKTAEGRDKLLAVTSKLGKVNPAYFSVTFGAGGSTQQGTIDTVLD
IQQQGFSAAPHLSCVGSTKENIRQILANYQSQGIDRIVALRGDIPSGTLDAGEFRYANEL
VGFIREETGDHFHLEVAAYPEIHPQANNAQTDLANFKQKVEAGANSAITQYFFNFEAYVR
FVEDCDKMGLTVPIVPGIMPITNYSQLARFSDMCGSEIPRWIAKRLEGFADDRESIKAFG
TDVVSELCQSLLDYGCPGLHFYSMNQAESSLAICRNLGVEGA
>A0A4Q1BUI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tremella mesenterica|TrEMBL
MPHLTSLLAQRNGPFHTFEFFPPRTEAGLVNLLDRVRRLASEPLPAPLAVSVTWGAGGAT
ADRSLELSEQITKLGLEVILHLTCTNMPKEKVDDALSKCKEMGITNILALRGDPPRSEEY
AVIPPTEPDLFQHADDLVRYIRAEHGDYFCIGVAGYPTPHLDSESVEDDLKWLKVKCDAG
ADFIITQLFYDVEGFESWIKECRRIGISVPIIPGVMPIQNFASFRRLVNLTHTPVPVSIM
SDLEPIRTDDAAVKRYGAKLATQMVRRLLSSSLVPGVHFCTLNLEKSVRTILENLGWSAE
SNQLKSSPLPRHNQLIDDDDVVAGTKQPAAPGLSISPSEASHLAQWGLKNKALPPAPKKG
LGNVGTTGPSGEDSWDEYPNGRFTDVRSPAYGEIDGWGSGLKITPAQALKDWGVPINSED
LSDLFCRYLRSDPTAPTTPFCDLPLSSESVKILPHLLKLNSAEMQHWTVGSQPAVDAAES
GDPIHGWGPRGGYVFQKAFVEFFVPLSKVDKIEQRLTRRTDGMISMYAGNKRGDFKTNTL
KDAVNAVTWGVFPGQEIVQSTIIEETSFLAWKEEAFDIWTEWSRLYPRLSPARKHLEHIA
DEWWLVSLIHHDYKDPEALWRFLLDPPSPQ
>A0A4Q2ZBJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
AVEDLYKTIVELEAYQPSFVSVTYGAGGSTREMTHELVVKIKQTTSVPPVPHLTCVGHSE
PQIEEILRRYAAAGVSNILALRGDPPRDWPNYDWSDCDFRHAADLVRFIRKFNESGAHPD
PRGFGIGVAGFPEGHPTTPNRLLELDHLKAKVDEGADYICTQLFFDNHDFFDFRDRCRLH
GINVPIIAGIMPVTSLSGMARMAELAAGARYPAKLLRALDRAKADPAAVEKVGIHYAAQQ
CAELLDHDVDGIHFYTLNKSKATREIYASLGLAASAS
>A0A3M7MRG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetothyriales sp. CBS 132003|TrEMBL
MHITTKLNAAHSLGRPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
ALTCEMVSAAQTNYGLETCMHLTCTDMERSKVDEALRRAYKSGCTNILALRGDPPREQDK
WKAKDGGFRYAKDLVKYIRTMYGDHFDIGVAGYPEGCDDEPDADRLIDYLKEKVDAGGTF
VVTQMFYDVDIFLNWVQKCRDRGITVPIIPGIMPISTHQAFLRRANWTKCHVPEKWHAAL
EPVKNDDGAVKEIGRDLVVEMCRRILDAGILHLHFYTMNLAQATRMILEELNLTPETSGV
PLSKPLPWRPSLGFGRREETVRPIFWRNRIASYIARTTEWDEFPNGRWGDSRSPAFGELD
AYGIGLKGSNESNIKLWGKPRSLREVGNLFVNFLEGRLDRLPWSEGSISAEADSIKAELI
KINRRGFLSINSQPAVDGAPSSHPVYGWGPQGGFVYQKAYLELFVLPSVIDEVMRRLEAN
KNLTYFAVTNNGTLRTNSPDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGHD
WSKCYPQGSGSRRLIETIMDECYLVNIVNNDFHQTHEIFGIFDDLENGIPGTVNGATSAE
VSQTQ
>A0A2E8MVT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MKVTEHIKAAEGKTLFSLEIIPPKKGDSIDSLFNHXDPLMEFKPPFIDVTYHREEYVYKN
RGNGLLEKKTIRKRPGTVGICAAIKNRYNVDPVPHIICGGFTKEETENALIDLNFLGIDN
VLVLRGDSIAEEKTFKPEPDGNAYAIDXVDQVVGMNEGQYLDEDLQNAVPTTFCIGVAGY
PEKHFEAPNLTSDLKYLKQKIDHGAEYIVTQMFFDNQKYFEFVDKCREAGINVPIIPGLK
PITAKSHMTILPSIFHIDIPDELYTEIEKCKDNKQVKEVGIEWGIKQSKELMAAGVPVLH
YYSMGKSDSVERIAKSLF
>A0A2E4WU51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MPQKSDKIKVSFEFFPPKNDQAVNSLWLNIKRLEPLNPAFISVTYGAQGSTRENTHNLVK
DIKKRTKLVPAAHLTCIGSSKLEIERIAEDYWNSGIRDIVALRGDKPKVQTKNFSDEFKY
ATDLILVLKKRYNFNITVSAYPEMHPDSVSLEQEYDVLKKKVDLGASKAITQFFFDTRFF
TKFLDGAIKRGIKIPIIPGILPVTNCKKTIEFAKKMNCKMPTWLLKMFEGLDSEPETRKL
VAATIVHDQCKTLINEGIKDFHFYTLNRADLSFAICHILGLRTLKD
>A0A2E6MQU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MIKQNDDIKVSFEFFPPRDKNTELSLWKNLKRLEPLRPQFVSVTYGARGSTRERTHQLVK
EIKSKTTLEPAAHLTCVDSGVDEIIDIANKYWNDGITHIVALRGDKPKIKKKINNKLNYA
TDLIKVLKNCYNFDITVSAYPECHPDSKSLEQEFEVLKKKVDLGATKAITQFFFDTGKYI
DFVDQAIKKNIKIPIIPGILPITNCQRTLTFAKSMNCSIPNWLQKMFTGLDSDPKTRELV
AASIAAEQCQSILKEGINEFHFYTLNRADLSFAICHILESRFNEKVI
>B5RV11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)|TrEMBL
MRISEKLSQAHSTSSPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALHKAYVSGCQNILALRGDPPLD
GSESTGDFKYAKDLIRYIRNKYGDHFNIGVAAYPEGHPEEEDEDKTLQYLKEKCDAGANL
IITQMFYDADNFIKWCSKLRKIGIDIPIIPGIMPISTYAAFIRRAKWSEVVIPQHFLDAL
EPIKEDDYLVRAKGTELVSEMCTKLIKSGYVNHLHFYTMNLERATIMILENLNLIESVKS
HEVIGGSDLPWRKSLHPQRSKESIRPIFWQNRKYSYISRTSTWDEFPNGRWGDSRSPAFG
DIDLFATDLLRQSPKKAFDLWGHPGTLKQFSDIIISFLSGKLNSLPWSDSAIGQDSEIIV
DNLIALNKKGFFTLNSQPSLNAIKSNDKVYGWGPKNGYVYQKQYLEFFVHKDIIPALLHQ
IDNYNRGQGDSNSSVLTYYAVDQKGKLFSNTKDDDINAVTWGVFPGEEILQPTIVEKVSF
LAWKDEVYRLITEWIKIFQSDFVKDVNITKEDVDAFVKLMTNFNDEYVLCNVVNNNFIDD
NQTIFKLIDELNIPDLK
>A0A553SR37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niallia circulans|TrEMBL
MNFREELQKRILIGDGAMGTLLYSNGIDNCYEELNITHPTRIETIHSAYLEAGADILQSN
TYGANYYKLKRYGLEEEVSTINRKGIAIARKAANGKAFVFGTIGASRSFRKSDLDLDEIK
RCFREQLYSQLIENPDGLILETYYDLEELEMVLNIARNETDLPIIANVSLHETSYLQEGI
HLNEALLRLEALGADAVGVNCHLGPHHMIRSLEEVPLPKKAFLSVYPNASSLPEYVDGRF
VYEAVPEYFGYSAVNLRNQGARIIGGCCGTTPNHIAEVKKALGNIAPITEKKIIKRKVEM
IEAAAKETKKGLYEKAKMERTILVELDPPKKLGIKEFMKGAKALHKAGVDSITLADNSLA
SPRISNVALGTILKKEIGSEPLMHITCRDRNMIGLQSHLMGLQTLGLNEVLVVTGDPSKI
GDFPGATSVYDLSSFDLISLVKQFNEGLSYSGQSLGQRTNFKIAAAFNPNIRHLHKAVER
MEKKIACGAQSFLTQPVFSTNQIEEVYEATKHLDTPIFMGIMPLTSTRNAEFIHNEVPGI
KLPDTVRKAMASAGNNPIKARAEGLAIAKELVDAAAERFKGIYLITPFLRFELTEELSKY
IRAVDNKHVVELTANEQ
>A0A7Y7QSP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sanguinis|TrEMBL
MTNTILTRAEAALAHEEPLFADVGGDIAVSFEFFPPKTEKMDAQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTLAAAAHLTCVEATREEIDQVAQEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPESTDKVADLDNLK
RKIDAGATRAITQFFFSPEAYFRFRDDAAAAGITAEILPGILPVSNVAQTRKFAALCGAS
IPEWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKGFHFYTLNRAELAYAISHLL
GVRGKKAEAVVAA
>A0A1G3K4F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium RIFCSPLOWO2_12_FULL_63_15|TrEMBL
MTLPSIHPNWDLPPKGMTDGYSLEITAKDIDALREAAPTMAAETPVAVTFLPGESLEARI
AAAKLVRSLGFEPMPHFSARRLESGDDFETYLAAVVREAGVQRCFVIAGDPPEAAGPYSD
SMALIRTGAFERAGIKAIGVGGHPEGHPNMTPDQCFAVLIEKCAEIEQRGMAPLIVTQFS
FDAAPVLSWLAELRQRGIDAPVRIGIPGPAGIKTLMRFAARCGVGASASVLTKYGISITK
LIGTAGPDKLVDALASGLGDQHGKVRLHFYPFGGLTKTVEWINDYTARH
>A0A5J9W8X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eragrostis curvula|TrEMBL
MKVIEKIQEAAADGRTLFSFEFFPPKTDEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVQHIRAKYGDYFGVTVAGYPEAHPDAIQGEEGATLEAYSNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGIACPIVPGIMPINNYKGFVRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGVHLGTEMCKKILASGIKTLHLYTLNMDKSAIAILMNL
GLIEESKVSRPLPWRPPTNVFRVKEDVRPIFWANRPKSYITRTRGWDQYPQGRWGDSRNP
SYGALSDHQFARPRGRGKKLQQEWAVPLKSVEDISERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLD
QLVEKSKVFPSLTFLAVNKDGESFSNIPVNAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWTRGWASLFPEGDSSRELLEKVQKSYYLVSLVDNDYIHGDLFAAFKEI
>Q1QAS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter cryohalolentis (strain ATCC BAA-1226 / DSM 17306 / VKM B-2378 / K5)|TrEMBL
MTKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALCA
RGETDIAPHMSCIGDDKSEIAELLEHYKSLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFKLDVDNLVNKYQAGANASITQFFYNADSYLYLR
ESLEKRGIDTVAQPLVAGIMPITNSSNLMRFADSCGADIPRYVRKQLADFGDDSKAIREF
GFEVVYRLCERLISEGVPAMHFYSMNKVEPNKRLIEALGLIA
>A0A1I3AE34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus aminovorans|TrEMBL
MSPHHDENPAGAHLPLEPLPGHASRGRLERVLRRGEFAVTTELNPPDSADPEDVYERAAV
FDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIYQISCRDRNRIAIQGDVLGAAAM
GVQNVLCLTGDGVQAGDQPGAKPVFDLDCMSLMETIRTMRDEGRFLSGRKLTTPPAMFMG
AAINPFAPPYDFRPLRLAKKIAAGAQFVQSQYCFDVPMFRDYMARVRDLGLHEQCFIMCG
VGPLTSARTARWMRANVPGVHIPDAVIARLEGAADQKREGKRLCIDIIDEVKEIAGVAGI
HVMAYRQEEYVAEIVHDSGVLKGRRPWRPEPRADDALVAGRLDHILHDDRAETPQQILTD
AQAAPHPATT
>A0A2M8BG58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium CG_4_9_14_3_um_filter_60_33|TrEMBL
MTSSTNFAVSVEFFPPKTPEGVEKLRVVRQQLYALNPEFCSVTFGAGGSTQEGTFSTVRD
ILSEGVSAASHFSCIGATRERVREQLGTLKAMGVKRLVALRGDLPSGYGTGGEFHFASDL
VAFIRAEMPDDFHIEVAAYPETHPQARSPEADLKAFAVKVQAGADSAITQYFYNSDAYFR
FLEDADALGVSVPVVPGIMPIASSSQLLRFSDACGAEIPRWIRLRLQSFGDDGASIKAFG
LDVVTDLCEQLRAGGAPGLHFYSMNQSESTLEICKRLGL
>A0A417GHF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM29-11AC|TrEMBL
MKIRDILAQGKPTLSFEVFPPKAEDKYDSVEEAAIRIARLKPAFMSVTYGAGGGTSKYTV
DIASSIKNQGVNALAHLTCVSSTKEEVRRVLGELKTRGIENVLALRGDIPEGGPLAHDYR
YASELIREIRSFDGDFCIGAACYPEGHVESANKTEDIEHLREKVEAGCDFVTTQMFFDNN
ILYNYLYRIRERGITVPVVAGIMPVTNARQIDRICRMSGTYLPARFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAEQIKNSLSEIL
>A0A7H4GL84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenzhouxiangella sp. AB-CW3|TrEMBL
MSDSAPQLSFEFFPPRSAAQQVAFERARDRLATLQPAYMSVTFGAGGSTRDRTRETVLSI
AEATGIEAAPHISCMAESDDDIEALLDDYRAHGIKRLVVLRGDRPSGSGAGVFPYAVDLV
RFIRKRYGNTFHIEVACYPEHHPESRTPDDDLKHFRDKVAAGADGAITQYFFSADSYFRF
VDEARSLGVSVPIVPGIMPITNYTGLARFSQMCGAEIPLWIAKRLKAWDDAGDRESIAAF
GEDVVTELCRRLLDGGAPGLHFYTLNRARATLALCRNLGLDPQPAATGS
>A0A8I1JE13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas rhodesiae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAAQLASYQPDFFSCTYGAGGSTRDRTINTVLQLE
SQVNIPAAPHLSCVGDSKADLRGLLTQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANSGANSAITQYFFNADSYFY
FVERVRALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7X6NLD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierellia bacterium|TrEMBL
MKIIDKFTEKRPLISFEIFPPKADYPIDTIFNAIDELYKLAPDFISVTYGAGGSTKDKTV
EISSYIQNRYNLTSIAHVTCITSARKEIINILNSIKENNVHNVLALRGDYPKDCKISPPI
DGFKNSMELIEFIKSNSNLCVGAACYPEKHPAARSLYDDIDFLKRKMEAGADFLVTQMFF
DNDLFYDFYDKIRKKNIDLPIFTGIMPILNKNQINTILNLTGNSIPNKFKMLLEKYENNP
EALKEAGMSYAVSQIIDLLSWGVDGIHIYTMNKPSTAKKILENISAIRSVLTHESKFY
>A0A6B3ME60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symploca sp. SIO2E9|TrEMBL
MSKAIQNSKTQVATDKLSLHNYSADTTATKKTFRTAAESGKFLITAEVTPPKGGNPAHMV
KMAQTLKGRVHAANITDGSRAVLRMSSLAASAILLQQGIEPICQLACRDRNRIALQADLM
GANALGIHNILALTGDPVKAGDHPEAKSVFDLESVRLLQLISKLNQGCDAHDKPLTDEVT
DLFAGAAVDPQLKSWSGLQRRFERKIEAGAQFFQSQLITDFERLEKFMEQIAAGTNKPIL
AGIFLLKSAKNARFINKYVPGVNIPEALIERLSAADEPLLEGMKIAAEQVQIAQQICHGV
HMMAVKREDLIPQILDLAGVQALSN
>A0A1S2DYN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium vitis|TrEMBL
MAHTSSKKDQARPFKLSFEFFPPKSEEMEAQLWATVDELTGWEPEFVSVTYGAGGTTKAP
TLAAVRRLLAETPLATASHLTCVGATREEIAQVVEDFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGFENAAALVKGLKELGDFEISVSAYPEKHPESADLAMDLDMLKRKVDNGATRALT
QFFFDNDIFERYLDKVRAAGISIPIVPGIMPILNLTQLKRFAGMCGTSVPAMLDKRFEGL
DDKPTERANVAAALAAEQIADLQGRGIDEFHIYTMNRAPLVHATLERLGLQRSDTAVAER
AGVVA
>A0A7X8AXB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierellia bacterium|TrEMBL
MRIKNLFEEKNLVYSFEIFPPRPNYPLESIYSPIDELSQINPDYISVTYGAGGSTQNNRT
AMLSSLIKNKHQIESVAHLTCIGATRDNIDKILDELEANKVENVLALRGDIPSSGLVEGD
FKNSQELISYIKERDNFGIAAGAYPEGHIETKVKDFDLEVLKYKEEAGADYFVTQLFYDN
NVFYEFLNKVEQKGIKLPIQPGVMPVINKRQIERTIELSGASLPEKFIKIINKYEHDKLA
LRDAGIAYATEQIVDLISSGARGIHLYTMNNPTIAKTLTANIKSLIKSVNSRE
>A0A2E9SMN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spongiibacter sp|TrEMBL
MSKRYSFEFFPPKTEAGRDKLKQTRTELNALDPDFFSVTYGAGGSTRDNTRGIVLETLXA
GIDVAPHLSFGGDEEAEVLSLIEQYREAGVRRIVALRGDIPSGMGATRLIYARELVEFIR
KHTGDHFXLEVAAYPEIHPDAPSYDQDIQFLKDKLDAGANSAITQYFFNADAYFYFLDAC
EKAGIDKPIYPGIMPITNYSNLARFSRNCGAEIPRWLSRKLEGYGSDLESVAAFGEEYVT
ELCQILLEGGAPGIHFYTMNQVQPVXRMMEACKASHP
>A0A172XT63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium glaciei|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYGNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERKITRMRPGTLGICSAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTKGGHASAMDLVHQINDLGRGKYLHDEQACEENNKFCIGVAGY
PEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVTKAREMGITVPIIPGIK
PIATKRHLKLLPQVFKIDLPEDLINEVESAKNNEAVKQIGVEWAINQCKELLDFGVPVLH
FYSMGKSDNIKKVAGELF
>A0A4R7S7E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecobacter fusiformis|TrEMBL
MSLPADLTSCLMHIADILANQRPTLSFEFFPPKTAEASEALYQTIGELEAYKPSFVSVTY
GAGGSTRELTHDLVVRIKKTTTLDPVPHLTCVCHNEADIASILERYAEAGVSNILALGGD
PPRNLEGYERKNDAFQHAVDLVSFITKFNNSHAHPDRRGFGIGVAGFPEGHPSTPNRMLE
MDYLKAKVDAGADYICTQLFFDNHDFFDFRDRCKLAGIHIPIIAGIMPITSASGMRRMAE
LAAGARYPAKLMRAIQRCGGDEEAVQRVGVHYATEQCRDLLEHGVDGIHFYTLNKFQATR
EIYASLGIRDSSAVRPS
>A0A358L4K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia citreus|TrEMBL
MSFFHASQREALNQSLAELHGQINVSFEFFPPRTSEMEQTLWHSIDRLSSLKPKFVSVTY
GANSGERNRTHTIIKGIKDRTGLEAAPHLTCIDASRSELRAIAQDYRDNGIRHIVALRGD
LPPGGGKPEMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVIAGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMTSMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVAVPA
>A0A2H6G4E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Abin11|TrEMBL
MPQDIIKTFSLEYFPARTEKGEQSLATTRKELSKLKPAFASVTFGAGGSTQDGTYQTVKT
IIEEDGLEAAPHISCISTNRNTLAKMLAEYRKLGVKRLVALRGDIPSGYGTAEHNELRYA
NELVEFIRRLTGDYFTIEVAAYPEFHPQATSAQADLINFKRKVDAGADSAITQYFFNPDA
YFRFIDDCQKMGLKIPVIPGIMPITNYKQLARFSDACGAEIPRWIRKRLESYGDDLESIR
EFGLDVVIRLCEQLLEGGAPGLHFYSMNRNEPVQTIWNHLKLSG
>A0A132BSA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tritonibacter horizontis|TrEMBL
MTCDPCAVKSDTAPQIAPIPVPVDLEETETVSTPEISFEFFPPKNLEASFRLWDTVQSLS
PLGPRFVSVTYGAGGTTRELTRDAVTTLHKNSGLKVAAHLTCVSATRAETLAIADQYAEA
GITDIVALRGDPPKDQGSFAPTEDGFASSVELIEALAAKGKFNLCVGAYPESHPEAASQQ
ANVDWLKRKLDAGATEALTQFFFEAESFFRFRDACAKAGIDTDRITPGILPIENWKGVRR
FAEACGTTIPAWLDEAFDKAQRDDRCDLLATALCSELCTELLEGGVKKLHFYTLNRPELT
RDVCHALGVKSKIRLENVA
>A0A2R3QAA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melaminivora sp. SC2-9|TrEMBL
MNTTSPALPVSFEFFPPKTPEGVDKLRAVRQQLYARKPQFCSVTYGAGGSTQEGTFAAVR
EILGEGVDAASHFSCIGATKGSVRTQLAQLKAMGVKRLVALRGDLPSGYGLGGEFHYASD
LVAFIRAETGSDFHIEVAAYPEVHPQARSADADLQAFATKVRAGADSAITQYFFNADAYA
RFVDDARRLGLDVPIVPGIMPILGATQLMRFSDACGAEIPRWIRLRLQGFGDDVASIRAF
GLDVVAQLCEQLLHAGAPGLHFYTMNQSAPTLALCERLGV
>A0A4Y4F8U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas halmophila|TrEMBL
MKFDDEPVPGYSLPVLPGHVSPGRLERVLRAGRFAVTTEISPPDSADPAEVLQRAAIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYATILQMSCRDRNRIAMQGEILGGAAMGSC
NLLCLSGDGVQAGDHPHARPVFDLDSLSLLNIAKGMRDGGHFESGRVIESPPRLFLGAAE
NPFVPPRHVRAQRLAKKVAAGANFIQTQYCFDTAALRDFMAEIGDMGLLEGPDRVHVLVG
MGPLGSARSARWIREHVPGVHIPDHVIKRLEGARDQREEGTRLCRDILQEVREIEGVSGA
HLMAYRQEGKVARIIEETGVLEGRVPWYPGRDNPAELNPEAASAVGPAATGSGW
>A0A0X8X9V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halorhodospira halochloris|TrEMBL
MESQKKHPRVFSFEFFPPKTDEGAATLRTTRQRLEKLNPAYFSVTFGAGGSTQDRTFETV
VDIQRQSSAEAAPHLSCIDSSRERLKEMILAYREEGVKYIVALRGDRPSGSGSGGEGDFR
YANELVEFIREITGDHFTIEVGAYPEFHPEAPGAFADIDNFVRKVNAGADSAITQFFYNA
QAYYRFVEDCEKRGVDIPIIPGIMPLMNFEQQARFSEACKADIPRWLAKRMEGMKDDPQG
RLEYGIDVITNLCEELLDAGAPGIHFYALNKAPVVERIWHNLGLSQETGGEQRRPEDIEL
PT
>A0A0X8C3V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium columnare|TrEMBL
MKVTEHIAKASGKTQFSFEILPPLKGQNIQCIFDGIDPLMEFNPPFIDVTYHREEYEYKE
LGNGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGNEYASELVKQISDLNNGKYLDADLQNTNATDFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIANGADYIITQMFFDNKKFFDFVSKCRKAGINVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMAVVKAKDNEAVKQIGIEWCIAQSKELVKAGIPVLH
YYSMGKAENIKAIAKEVF
>A0A0C5VQL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gynuella sunshinyii YC6258|TrEMBL
MSISTPVSFEFFPPKTEEGREKLLTTHATLSEQTPEFFSVTYGAGGSTQERTINTVIELN
NKGICTAPHISCIGASQEKITELLDLYKANGIKRVVALRGDLPSGMGATNGDFHYASDLV
AFIREQYQDQFHIEVAAYPEMHPQAVDFNTDLRNFMTKVNAGASSAITQYFYNPDAYSFF
VDQVRRAGSNIDIVPGIMPITNYTNLVRFSDGCGAEIPRWIKRKLEAYRDDVKGLQAFGA
DVVADLCRHLIDRGAPALHFYSMNQSEPTLNILDRLS
>A0A8B5TJJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-3-15|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHQVDAVIQEFTDMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEVAGS
AAA
>A0A7V3AMT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MANADTLSLAARMGAGRPPTFSFEVFPAKTPEGHEKLIGLVGELCALRPDFISCTYGAGG
GSRERTFDVVERIQKHHGIPAVAHLTCVGHSRADISRILDDLDRRGIRNILALRGDPPAE
GAPACPAPDCFAFAHELVQAIRARFGASACIGVAGFPEKHPLAPDADADARFLKQKMDAG
ADFVITQLFFDPEMYRMYVTRLRALGVTARIIPGVLPVVDFRAVERFCARCGAGIPPAMR
AVFEPIADDPERTRAAGVRFTVRLCRTLLDAGSPGIHLYTLNKLEPARTIMAAVRSLDAP
AL
>A0A6N8H9H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium rakeshii|TrEMBL
MKVTEHIENANGKTLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYTYKE
LANGLLEKKVVKKRPGTVGICSAIQNKYGVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGNQYASELVSQIVNLNKGIYLDDDLQNTSATDFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGASYIITQMFFDNKKFFDFVDKCRKEGITVPIIPGLK
PLSTKKQLNQIPYRFKVDMPDELIMEVVKAKDNDAVKQIGIEWCIAQSKELVKAGIPVLH
YYSMGKSDNIKAIGKEIF
>A0A7C4B2Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MGILQKLSERKTAYSFEFFPPKTDTPLEAVYDAIEKLSSFDPAFISVTYGAGGGNKDRVV
EIAEHLKNRNYEAIA
>A0A7W0JZI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MTASRPRARADTGSARLAELLRNARFEVLPLAGIEDEVLAHLGTDVKVTVTASPRKGLEA
TLELTERLTRAGYATVPHISARLVRDRAHLSELLERMHAGAVRELFVLAGDAADPAGEFA
GAAELLEAMGSRRADFDAIGITGYPESHHLISDEETIRAMFAKAPMATHIVSQLCFDAEV
IAAWIGEVRRRGTDLPIWIGVPGNVPYAKLLSVSMKIGLGESARFLRHHGNWISRLVTRQ
FKPDRLVRELVPCATEQAARVAGFHLYTFNEVARTERWRRAALERMGG
>A0A8E4G193|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. KK2020170|TrEMBL
MKVTEHIQNAKGKPLFSFEILPPLKGQNIQSIFDNIDPLMEFKPPFIDVTYHREEYEYKE
RENGLLEKKIVKKRPGTVGICAAIQNKFKVDAIPHILCGGFTKEDTENFLIDLDFLGIEN
VVALRGDAVKNEIYFKPEREGHRYASELVKQISSLNNAIYLDDELQNSTATNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIANGANYIITQMFFDNQKYFDFVEKCREEGITVPIIPGLK
PIATKNQLNLIPHRFKVDLPDCLIMDIVKAKDNEAVSQIGIEWCIKQSEELIKNGVPVLH
YYSMGKSNNIYKIAQSLF
>A0A1G7Q3V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia phenazinium|TrEMBL
MNPLEISFEFFPPKTEDGIEKLRATRAQLAPLKPKFVSVTFGAGGSTQRGTLDTVVDMAK
EGLAAAPHLSCIGSSKESLRAILNEYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQARSPRQDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDREAIRAFGLDV
VTDLCQRLIDAQVPGLHFYTLNNAAATKAICDRLGA
>A0A536ZHP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTRSVERIFSFEFFPPATPEGVAKLRATREQLAQLRPRFFSVTFGAGGSTRDRTLAAVVE
IQASGQRAAPHISCIATYRQHGIGHLVALRGDLPSGSADVGEFRYANELVEFIREETGDA
FHVEVAAYPEYHPQARTPHEDLANFKRKIDAGANSAITQYFFNAEGYYHFVDQARAAGVG
VPIVPGIMPILSFSKLARFSDACGAEIPRWIRRKLESFGDDASSIRAFGLDVVTRLCDDL
LAHGAPGLHFYTLNQASLTKIIWERLKLS
>A0A3N1NP51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinimicrobium koreense|TrEMBL
MTDTDQPQLSFEFFPPKTDQGREKLLNVRKKLSEFAPDFFSVTYGAGGSTRDNTKGIVKH
FKSEGVSVAPHLSFGGDDEATIIELIQEYKDAGIDRIVALRGDMPSGVGGGYQMVYANEL
VAFIRKHFGDHFHLEVAAYPEIHPQAKSYDDDVKFLKGKFDAGANSGITQYFYNPDAYFY
FMDQCHKAGITQPIVPGIMPIISFKNLTRFSDACGAEIPRWMRKRLEAYGDDSDSIKAFG
EELVTELCETLLENGAPGLHFYTMNQYQPSAQIVHNLGLQPE
>A0A537CVG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MASNLLTRLQSGDFVVTAEITPPVSTDPAEFISRALPLKGLATAVNVTDGAGARVHLSSL
AAAHFLVQNGIEPIFQMTCRDRNRLALQGDLLGAVSLGIRNVLCLAGDDPKLGDQPEAKA
VFDLDSRGLLAMAHRMRTEQRLPSGTEVKGGVRLVLGAADMPIDPPPHWEPKALRAKLEA
GADFVQTQFCMDVAVARRYARRLLDHGIAQRLPILIGVAPIPSAHSARWMREKLYGTLIT
DAQIGRLEGARDAKAEGNRICIEVLQQLAEIPGVAGAHVMAPQNFTEIPIVIAESGVTGK
KRKT
>A0A0E1M479|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 1303|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2H5AX92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora sp. MMS16-BH015|TrEMBL
MALGIPSTRTDRALTVRELLAAGSRSFSFEFMPPRNDLAESKLWDAIRRVEALDPNFVCM
TYGAGGSSRGRTVNLVGRIATETTLTPVAHLTAVDHSIAELRNIIGQYADQGVRNVLAVR
GDPPGDPAGEWIRHPEGVTYAYELVELIRSIGDFCVGVAAFPQMHPRSENWDEDIKHFVA
KCRAGADYAITQMFFEVEDYLRLRDRVAAAGCEVPIIPEIMPVTNARQLERFPLLSGSPF
PDELEARLRAVVDDPAALRAVGIEHATTMGERLLAEGAPGLHFITLNHSTATLEIYQNLG
LHQR
>A0A6B5ETQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIHEGVRLIGGCCGTTPEHNKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDNAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>S6GNM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Osedax symbiont Rs1|TrEMBL
MINHDEPVPGEMLPILAGHTSAGRLERVLRAGHFAVTTELSPPDSANRHDVYERACVFDG
FVDAMNATDGSGANCHMSSVGMCALLTRIGYAPIMQVSCRDKNRIAIQGDVLGGAAMGVT
NVLCLTGDGVQAGDHPEAKPVFDLDCMSLLETIRGMRDKAEFLSGRKISTAPQLFLGAAS
NPFAPPYDFRPYRLAKKIAAGAQFVQTNYCFDVPRFTEFMARSRDLGLLEKVFILPGVGP
MASAKTAIWIRDNVPGIHIPDAVIDRLAGAKNQKQESQNLCVELIQELSEIEGVSGIHVM
AYRQEESVANIIQRSGVLQGRTPWYPGRDEQLLQESSGK
>A0A3R9FD67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus sp|TrEMBL
MSLKTNVTYYPAMPSAFKEKLLSDEFIVTSEISPPKGVDVSSVFEEAGLVRDYVDAFNVT
DNQRAVMRMSPLAMGHLLKERGLDVIMQFTCRDRNRLALQSDLLGAYAMGMENVCIMSGD
YPTKGDNPGAKPVYDLDSVQLLGAMNQLEGGYDIAGNPLESAPSFTKGAVCNTEPDQPLQ
LMKLEKKAHMGIDFFQTQAVYDIGHFETFMEGISHMEVPVLAGLIPLKSAHMARFMNEKI
PGIRVGDELIARMESSTDPAEEGLLICAEQIRELKKVCRGIHLMPIGHYRHITALFEMAG
LHEKH
>A0A2S7N4Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pradoshia eiseniae|TrEMBL
MNLLERLKGEILVGDGASGTLLYSFGIDTCYEELNLTNPERIVALHKEYIEAGADLIQTN
TFGANYHKLKRYGLEGETARINREGVRLAKEAANGQVYVLGTIGGLRSVRKSELSLEEIG
VYFKEQLDALLQEKPDGLILETYYDLEELLSVLAIARKETDLPIVANISLHEVGLLQNGM
QVKDAFEMIKENGADIVGLNCRMGPYHMIRSFEEVPLNKETYHSAYPNASLPDLDNGRYV
YSTNADYFADAAKQLIEQGVRLIGGCCGTTPEHIRAIKRGILGLVPLTEKKEVISRKTHV
YTYEFKYPKKQTILGKVKQDPTILVELDPPKTLGVEEFMKGSKYLHEMGADAITLADNSL
ASPRISNVAIASMLKAEHKKNPLVHLTCRDHNLIGLQSHLMGMHTLGLNEVLVVTGDPSK
IGDFPGATSVYDLSSIDLISLIKQFNAGISYSGKPLGGQTNFEVAAAFNPNVKYIDKAVV
RMEKKIGAGADYFLTQPVFSVEKIREVYEATKHIQAPIFIGIMPLTSYRNASFLHNEVPG
ITLPEKVLRAMESAGTNTEACMRESLAISKELLDAAAEYFNGHYIITPFMRYELSGELVS
YASKKKSVISGEVFER
>A0A8B1CT44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPKKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A1Q8DDF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSRLLNQLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVESIHRSYIEAGADIIQT
NTYGANFEKLKRFGLEHKVKDIHKAAVAIAKRAAQPDTFILGTVGGFRSLQQEELPLSTI
QYHAENQIDTLVEEGVDGLLFETYYDLEELTNIVTTTRRKYDIPIIAQLTASNTNYLVDG
TEINQALQQLVTCGANVVGLNCHHGPHHMQRSFSHIALPENAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPQHIAYIKSSVKDLKPVTNKKVIPINRQT
NRAVTRTYKHNLTTKVKNGPTVIVELDTPKHLDTDLFFENIGKLDEAKVDAVTLADNSLA
TVRVSNIAAASIIRQRYDIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMNYFITQPVYSKAKIKEVYEATKHLNVPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLSQFKAVKDDKEKTKALSLRLSKELIDTVHEYFNGLYIITPFQRVDYSLELAAY
SKAITQNKEAIS
>A0A7K9IJ39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myiagra hebetior|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLRDKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWQEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6P0R7N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO3I5|TrEMBL
MNRFRNAVKSGEFLITAEVAPPKGADPTHMIKMAETLKGKVHAINITDGSRAVLRMSSLA
ASIILKNHKIEPIYQVVCRDRNRIALQADLMGASALGLHNILALTGDPVKAGDHKDARSV
FDMESTRLLKMIAKLNQGMDWNEKVLPDGPTDLFVGAAVDPQSPSWSGLKRRFERKLLAG
SQFFQSQLISDFDKLEKFMNQIAVDSNKPILAGIFLLKSAKNAAFLNKYVPGVDIPEHII
NRLANAEKPLQEGMKIAAEQIKMASNICHGVHLMAIKREDLIPQILDMAEISPIRVS
>B1ZRF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1)|TrEMBL
MHTLREKLEQADRFLIGTELVSVRGGMSERSAVKARTFANDLVDADAIDWISITDNAGGN
PQLAPTALGKPILYAGKEVVIHLTCKDLNRNALESEAWLLHSEGFNNILAMTGDYPVAGA
GGTAKPVFDIDSVGLISMLDQMNRGLDPNVGQSGPRKPRFEGTNFLVGAVTTNFKLHEGE
VMPQYAKLAAKIGVGARFIINQIGFDARKQSELLAYLRAHELGHVPLIGNVYLLSPRVAE
LFAEGRIPGVVVSPALRELCRRHAGGADGGKAFFTEFAAKQIAIYRGLGYRGVYLGGVHT
FPAIQQILTVERSFAPGDWRQFTREIAFSRPGEFFYYAQNDATGLADPTRRASIAARPSK
HVSALYHFSKWMHNVAFTPGTLLARWGARACASAADPMQGPKPLRLVEHASKAVLFRCKD
CGDCSLPEIAFLCPESQCAKNQRNGPCGGTRDGRCEVDGFGDCIWLRAYERLKHDGHEQT
MLAHTPVVQDQSLRGTSSWANAWLGRDHTAKPKPVPGDVGSMPPSPADAPPSSSSPPP
>A0A1Y4IB91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides distasonis|TrEMBL
MKVIDLIRDSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKKKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIVHGVPSLHF
YTMMASDSVYKIAKEIY
>Q2YM35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella abortus (strain 2308)|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A1Q5M2N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB03234|TrEMBL
MRDLLATGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRAGTVKA
TQEIAADTTLTPVAHLTAVNHTIAELRNMIGQYADADIRNILAVRGDPPGDPMGEWVPHP
QGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVDKCRAGADYAITQMFF
FPEDYLRLRDRAEARGCDTPIIPEIMPVTSVKQIERFAQLSNAHFPPELKERILAVKDDP
AAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGLHEQS
>A0A3Q3X4E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mola mola|TrEMBL
MVNQVQRGDGSWQLCRSDSSGASNSGGESSKESSRCSTPVLDADRADRLRDKMRKRIESR
DHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCKQTKEKISGYLGKAKHLGLKNIMALRGDPMGADWEEEEEGFNYAI
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAVGVNCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIQQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLQMWGEELQSEESVFEVFTCYITAQPNRSGRKVMCLPWNDEPLAQETNLLKAQLEKVNR
RGVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKWLALKMLQLFLKEIVQPTVVDPVSFM
YWKDEAFALWIEQWAKLYEEESPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQVIDDMFE
LLDAPPEALDSSL
>A0A151AN03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium colicanis DSM 13634|TrEMBL
MYIKDMFSSKKTVISFEIFPPKKDYSIDTIYDTIDELAPLNPNYISVTYGAGGNNKDRNK
TVEIASIIKNKYNIEALAHLTCISSTRDEVEEVLKSLRDNNIENILALRGDIPQDPNFKF
PTPLHFKYAVDLIEKIKSTKDFCIGGACYPEGHIECSNLNDDIQNLKKKVDAGADFLITQ
LFFDNNFFYNFREKVDEIGINVPIEVGIMPVTNSRQIKRITSLCGAYVPKKFEKIMDRYI
DKPQALKDAGIAYATEQIIDLLSSGVEGIHIYTMNNPEVARRIVSNIDSVVKAINNNIAV
>A0A4V3CVJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oharaeibacter diazotrophicus|TrEMBL
MRQSHNLADLDIGVSFEFFPPKTEKMEENLWVAIERLAPLGPRFVSVTYGAGGSTRERTH
ATVARIVRETALKPAAHLTCVDASRAEVDEVVRGYWSAGVRHVVALRGDPVGGVGARYVP
HPDGYASTPELIAGIRAIGDFEISVSAYPEKHPESPDVPADIQILKRKVEAGASRAIAQF
CFDNDVFERYVDRVRAAGIDVPIVPGIVPVVNFTQTAGFARRAGASVPAWLAERFEGLED
DPVTRQLVAAAVCAEQVMDLIDRGYREFHFYTMNRADLVYAVCHMLGLRPKRPKPAAGAE
AA
>A0A415BIA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM13-34|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCNLSPSFVSVTCSAGGSGN
GAATAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNVSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELANKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A149V706|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter cerevisiae|TrEMBL
MTDRLNGLVSEQRIGNLLSCSRDMPPPALSFEFVPPRTDSMEQRLWQCIRRLAPLSPHFV
SVTYGAGGSTQASTYATVLRLRRETDLVPAAHLTCVGATREEVDAVARRYWEAGVKHIVA
LRGDPPAGAVGYTPHPGGYAYASDLVAGLRRIADFDISVAAYPETHPAALSPDADLDNLK
RKLDAGATRAVTQYFFDASTCLRFLERCRAAGITAPIIPGIMPVSNYEQVARFSALCGVT
VPAWLTRLFEGTNGDLELRRIVASIVAVEQIRTLQANGINDFHISTLNRAEPIYAIAHIL
GLRATDRCVVDHLADYSEHEEASDEQEAETESDTPGRAEEGASPFMLRTMFG
>A0A6N6PDX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MELIRDIYAAKRATGKPIISLEFFPPKTDEGDRALLEKHIPTLMTTRPDFCSVTYGAGGS
TRDKTLMIVDRIQREHNLTALAHLTCVNHTRQQVAELLEKIKTVGCKNILALRGDPPTGG
EFVATPGGFEYSSQLVKFIREQGGFSIGCAGFPEGHIACKEGKLVDWSRLKEKINEGADF
VITQMFFDNADYFQFRDHLTKNGVNVPIIPGIISIVSATQIKKFTVMCGAKIPPALGAKL
DAIGTDDTAAAEFGIEYCTKQCEELLRCGAPGLHFYTLNKAASTVQVLKNLKQA
>N9RB88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 3623|TrEMBL
MAQNSPFLNFFIMSLFSQCLEQKQFCILVEYLCSNRDTPAVPPSLAGYPAMMTLADRVHS
DEDPAPLELAQQYAPEIEKLLHFSGKGRDIQEFERFLDQAEQHGYHNLLLLSGDKLKNHN
SGREIPAQRSRYLESVSAVMAAKQRHLFNIGVAFNPFKYTEAERDAQYLKLHKKIKAGAD
FLITQLGFDLDCLQHSQSFISQHYKQFPLIACVMPLTLKRAQFMLKHQVAGLVIPAHIVH
VLKSEYETDPVQAEANVYARCALQILICKHLGFVGVHLSACHKLSEQQKLEQFLKQYENW
SLAACEKAWKQLWRMETGLELKPELATFSKPVPPAQILKYKQMHLMHQLFFASHAALGFG
RFIFKANFWNKARPDQLLLKMEHWSKHPLVGCESCGHCRLDDTLYICPETCPKGLANGPC
GGTSLDRCEFGDRECIHSVKARLAKRLDQTEVLRSKLIPAISIETRYTSSWKNWFKHSES
H
>A0A7L1G4T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Indicator maculatus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLRDKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEEDLKYLKEKVFAGADFIITQLFFRSETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNY
HIVNVQGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7H9FCB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIAVPIHAGIMPILNRNQALRLLQTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3S1NCU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.010.02.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTKLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYRSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFRQVANFSARAGAHVPGWLAERFE
GLDLDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A538NDX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
ILLRYARSAIGNILALGGDRPRDIPYDKARDSFQHAIDLVKFIRRFNESGAHPNRRGFGI
GVAGFPEGHPATPNRLVEMDHLKAKVDAGADYIVTQLFFDNRDFLDFRERCALVDIHIPI
IAGIMPVTSMNGFKRIAELAGGARFPAKLLRALQRCQNDPEMVRRVGVHFALEQCHDLLD
NNVAGIHFYTLNRSDATRVIFDSLGIPRRRSAQAAAVQSSDEVGKRLAN
>A0A388PH03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MLRDAFLSRLRSPDRPTVSVEFFPPKKPEEAAAMLDTARALQPLGIDFASFTYGAGGSDR
STVLEYGSKLVQAGFPLIAHLTCVGHSRAELADIIAKYDDAGFAGILALRGDPPKGQTEF
TAHPEGFAHALGLVDLIRRERPGRFAIGVAGFPERHPSSPDDLSDIRHLAGKVAAGADFV
TTQLFLDNEDYFRFVARARAAGVSVPILPGIMPVLSLKQARRFCGFCQAKIPAALIQELE
ACGEDEEAQRKVGVSWAVRQVRGLLGRGVPGYHVYILNRSQSALELFAQLKF
>A0A2V5LP40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITEIMRGHSPTFSFEFFPPKTLHAAETLYQTIRDLESYMPDFVSVTYGAGGSTRELTH
DLVERIQHTTKLDPIPHLTCVCHKEEEIDAILLRYAKSVIGNILALGGDRPSGMAYDKSR
DSFQHAIDLVKFVRLFNESGVHPDRRGFGIGVAGFPEGHPATPNRLVEMDHFKAKVDAGA
DYIVTQLFFDNRDFFDFRERCGLAGVHIPIIAGIMPITSITGLKRMAELAGGARFPAKLL
RALQPCQNDSDMVRRVGIQYALEQCHDLLANDVAGIHFYTLNQSGATRMIFDSLGIPRHR
NLQASSV
>A0A2D6UFF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MKQSLXXSSLLDEGRPLRSVEFFPPKDEAAGERMLQAAAEIKRLQPDFVSITYGAGGSTR
ATSLKYATLLQEEFGFRVMPHLTCVGHAKSELREIIEEFHTLGFRNIMALRGDPPKGKTN
FQPHPDGLRYANELVSLIKELHPDISIGVAGYPETHPEASSPAEDITNLSRKVQSGADFI
TTQLFFDNQAYFRFVEDCREADINIPVIPGILPVLNLPQVRRFCEMCQAALPNELEKSLL
XTGENKEAARDAGIDWAHNQVSDLLGKGAPGFHLYILNRARAIAKLTERLIGEGLIEAXX
KXVAFLGRXFGK
>A0A2V5ZS38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITEIMRGHSPTFSFEFFPPKTLHAAETLYQTIRDLESYMPDFVSVTYGAGGSTRELTH
DLVERIQHTTKLDPIPHLTCVCHKEEEIDAILLRYAKSVIGNILALGGDRPSGMAYDKSR
ESFQHAIDLVKFVRLFNESGVHPDRRG
>B8JEQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258)|TrEMBL
MRITDLLRFARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTR
AKTIELVKRLKRDAEVEAMAHVTCVGASRDEIAAVLDEVAEAGIQNVLALRGDPPRGQGG
FVPHPDGFTHASELVAFIRSQPERWRFCVGAAAYPEGHPETRDLAQDLRHLKLKVDAGSD
FLVTQLFFENAHYFRFVERARAGGVEVPVVPGIMPFTNVEQVERFTAMCGAAIPPPLRAA
MEVRRADPESARELGVAYATLQCADLLRRGAPGIHFYTLNRSPSTRAIVAALRACEPWRG
>A0A2V6BXW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRGDAPTFSFEFFPPKTPEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRGLTH
DLVERIRHTTKLDPIPHLTCVCHNEEEIEAILLRYAKAAIGNVLALGGDRPTGIAYDKSR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLLEMDHFKAKVDAGA
DYVVTQLFFDNRDFFDFRERCALADVHIPIIAGIMPVTSINGFKRIAELAGGARFPAKLL
RALGRCQNDPEMVRRVGLHFAIEQCHDLLDNDVAGIHFYTLNRSDATRVIFDSLGIPRRR
NTEPSSV
>A0A2V5QCR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDTMRGSSPTFSFEFFPPKTSEAAETLYQAIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQNTTKLDPIPHLTCVCHNEEEIQAILLRYAKSAIGNILALGGDRPAGIAYDKSR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDYFKAKVDAGA
DYIVTQLFFDNRDFLDFRDRCALSEIHIPIIAGIMPITSIRGCKHMAELAGGTRFPARLL
RALQHCQNNPDLVRRAGIQYALEQCQDLLDNDVAGIHFYTLNRSDATR
>A0A7W9J2Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella italica|TrEMBL
MANGFPSTLPGSTPTIRELLATGDRSFSFEFFPPKTPEAEEVLWRSIREIEKLRPSFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTAVAHSRDELRSVIGAYAGAGIRNVLALR
GDPPGGPRQPWVAHPEGLNHAIELVELVRTLGDFCVGVAAFPDKHPEAADLDFDARVLAE
KAKAGADYAITQMFFGADDYFQLVERASALGCDIPILPGIMPVTNIKQIHRMAELTGMAL
PATVTDRLHAVEGDPAAVRAVGIEIASELCDELLTGGAPGIHFITLNRSTATRQVYLNLQ
GTTV
>A0A1A5XU55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus sp. WF146|TrEMBL
MDLTTKKDLREYLQDHLLVGDGAMATQLYRSGVPVGVSFEELCLTNPRLVHDVHKAYYEA
GARMMETNTFGANRDALARYGLEHKVTRINRVAVTIAREAAQDDAYVVGSIGSILAGRVR
KKVLDEYRDQFEEQAIALLHAGVDGLILETFLDLEELLLAIDVIRPLTGLPLICQLATLD
VGRTRDGYTLTEAFSHLQKAGADIIGLNCRLGPAEILRSFESARVPDGALLSAFPNAGRL
GLSDGEYAYKSSPEYFAESALRLREQGVRLLGGCCGTTPDHVRAMAEALKGLAPQARVNP
PDELTERPSVSSFSVRDRQKPSIVERVKTGTTIIVEFDPPKDLDTEGFLTGCCELHKAGA
DAITLADNSLANVRMSNMALGAIMKSQYGIDPLVHIACRDRNLIGQQSHLMGLHALGIDQ
VLVVTGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGISFSGRPLKQKAQFIVGAAFNP
NVRHIEAAIKRLEKKVEAGADFIMTQPVYDAESIRLVHEATKHIGIPVFIGIMPLTSSRN
AEFLHNEVPGIKLSDEARERMKRVQGEAARQEGLKMAKELLDVAITYFNGIYLITPFNYY
AMSVELIQYVRQQSHLLKAAAKA
>H3SQ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus dendritiformis C454|TrEMBL
MKDLRQVLQGEIIVGDGAMGTYLYQLGYPVGISYESLNISEPERIRDIHREYVSAGARLL
ETNTFTANREKLSKHGMEKQVKAINRAAARLAREAAGGQAYVVGALGSIRAGKRENIETD
QVKRDYTEQLSALLEEGVDGIMFETFYDMEEMKLAVQIVRALDDRIPIICQFAVEESHRT
KDGLRLLDAFRLLREEGADVVGLNCRMGPNGLMRAMEDLTGRLALPMSAFPNAGLPDYVD
GRYNFVATADYMAESAVRFAELGARIIGGCCGTTPEHIQAIAQALANAPAPALPTLAEEE
AQVQAVPPLEIGERGTAPASGQGKAASGPSLVDTVRQRHTVIVELDPPRDLDIAKFMLGA
QALKDAGADALTLADNSLAVTRMSNMALGYLALDKIGIRPLIHIACRDRNLIGTQSHMMG
LDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEIIRMIKQLNAGLAFSGKALKQRANF
VVGAAFNPNVKHLNKAIERLERKIEAGADYIMTQPVYDASLIERIAEGTKHLNVPVFLGI
MPLASGRNAEYLHNEVPGIHLSDEVRERMKGLEGESGRREGVAIAKELLDVAMKHFNGIY
FMTPFMFYEMTAELTEHVWQKAERLTDPLYRHT
>A0A7W3KY03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter ciceronei|TrEMBL
MNQFPLSRRSDIGNKIRVSFEFFPPKNDDMEARLWETVTRLEPLRPQFVSVTYGAGGSTR
ERTARTVKRILEESTLTPAAHMTCVDATREEVDQVIAEFAAMGVKRFVALRGDPKEGVGA
AYQPHPGGYANGAELVGALKAQGDFDISVSAYPEKHPESPDFVTDFDMLKRKVDNGATRA
VTQFFFDNDLYERYVERARKAGIYIPIVPGVLPIHSFTQVANFASRCGAHVPGWLAERFE
GLDKDPQTHALVASAVAVEQVLDLVERGVNDFHFYTMNRADLVVAVCHMIGIRPQPVVQG
SAAA
>A0A2M4BTY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles marajoara|TrEMBL
SIAEEPAVSSLREKLTQIFRPTSGEGEPSAVRSVFYSIEIAAKDDFNIDQLRRLTPPPVF
CSMPWISAENLRYEADFAQMPSLRLAEQLRREQITVVNHLSCYNLTEVQVDKLLSTQPSI
RNLFIVRGDTVSPDQQFQHSAQLLQHLRQYESTRTTTAATPKLTIGVGGYPGGHAESPSQ
EDELRHLADKVALGADFLLTQTLYDAASFFRYRDRCRAVGITIPIIPGIYLPHSYRQLQT
MLNITRVAMKPTVRALFEEHRNDTPEAFEAFVVQYFVELVRELLQSNAIEPGSSSDPVGL
VHFFTFNKFSLLEKVISQLKFGQQ
>A0A7C9GC19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fertoeibacter niger|TrEMBL
MSAPRISFEFFPPQTLDASFRLWETVQMLAPLKPAFASVTYGAGGTTRRLTHEAVTTIGR
NYGLNVAAHLTCVDATKSETLAIAEAYAEAGVTEIVALRGDAPKGASRFVPHPLGFAHSV
ELIESLAASGKFKIRVGAYPEPHPDAADPLADVRWLKRKIDAGASSAITQFFFDADTFFR
FRDACAKEGISAPIIPGILPVQSWAGTKKFAARCGTSVPARLDEAFAMAARDGREELLAL
TQCTTLCTRLIEGGVEDLHFYTLNKPHLTLQVCRALGLAPDVALEKVA
>A0A0Q0NEC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio metoecus|TrEMBL
MGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWNSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWNNGIQNIVALRGDI
PAGGGKPDMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRLRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPNWMVKQFEG
LDEDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>Q8PDM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)|TrEMBL
MSPDPPSRAATITDAYSLEVGAHDMPALTAAAPQIMRGSSMFIPYLPSQNDDARLAAAQR
VRALGFAPMPHLSARRIASRYALQAFVRRAVDEAGVERCLVIAGDAPSAVGPFSDSVSLI
ETGVFERSGIKAIGVAGHPEGHPSMPASAQWDVLERKCRSIAERGMAPLIVTQFAFDADT
VLTWLEALRARGIAHPVHVGVPGPAGVAVLARYAARCGVGACASMLSKYGISLGKLFGTA
GPDRFVDRLTAGLSEAHGDVSLHFYPFGGIAQSVAWVEQYRSRHARPLAD
>A0A0Q5XQ12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Leaf383|TrEMBL
MSGRTGNPPASPGDLLPGHSSRGRLEQVLRRGEFAVTAELNPPDSADPEEVYARAAVFEG
WVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQGDVLGAAAMGVA
NILCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDHAKFLSGRKLTAPPRVFLGAAI
NPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFRAYMDKVRDLGLHEHCHILVGVGP
MASARTARWIRSNVPGVHIPDAIIARLEGASDQKKEGKQICIDIINEVKEIKGVSGIHVM
AYRQEEYVAEIVHESGVLKGRRPWRREQDPADAGVAERLDAARAGEMQDQESLAETAAKR
PH
>V8IAU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis 27/7|TrEMBL
MSRQTPSLSFEVFPPNPEVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A0P0E215|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. No. 7|TrEMBL
MSSIAHRTVPVSFEIYPPRTPEGLPALHETIRRLAAVGPDFISVTFGAGGSTRDRSLEVL
THILRTTSVPPLAHLTCVGSTYVDAAAIIREFLDAGITRFLALRGDPPAGVREEDVFLGD
LESAAQLAQLIGRVQAERAPYTEAPVPGAPDAVRLAARERVQVAVAAFPNGHPRAVSEHD
DIDALLAKQAAGATLAITQLFFHADDYLGFVERARAAGVTMPILPGIMPIVSPTRLRRVL
ELTGEPVPAGLARALDAEPTADGQREVGLAHASALVRAVRDGGAPGIHLYAFNNHRNVLA
VLREAGIVATDARENTDTREKEIIR
>A0A0S3PVT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variibacter gotjawalensis|TrEMBL
MTPIANDRASRIADADRLNVSFEFFPPKTDEMERNLWDAIGRLAPLSPSFVSVTYGAGGS
TRERTHATVKRVVNETSLLPAAHLTCVDATKNEINDVIGSYRDAGVRHIVALRGDPTAGI
GTKFAPHPCGYETSAALVDGIKKLGDFEVSVSAYPEKHPDSASIDADIDVLKAKVDAGAD
RAITQFFFDNELYFRYLDRVRARGIDIPIVPGILPVQNFKQAKNFTSRAGATIPDWLAAR
FDGLDDDPATRKLIAAAVASEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGMRPAAAQ
KAA
>A0A3M6CEQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. maculicola|TrEMBL
MRSLLAQYKDAGIRRIVALRGDLPSGMGMASGELRHANDLVAFIREETGSHFHIEVAAYP
EMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFNFVERVEKMGVSIPIVPGIMP
ITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEDVITQMCERLLEGGAPGLH
FYTLNQAEPSLAVWNNLQLPR
>A0A1N7QEN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp. MFA1 R4|TrEMBL
MSESNSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQATNPSADLTHFVAKVKAGANAAITQYFFNADAYF
DFVDRARAKGVDVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPLAIWKELSV
>A0A1H7FAL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas daqiaonensis|TrEMBL
MRSPVARSATPDEFVLEAVPPEVERGEAGIEAAVERVAELHAALGLDAVNIPEIHEEKAK
SRQGERRRPFLPRVEPRVLAAHIQERLDIPCIINRVVVHLERDRQLDWFRETWEHYGIRR
FVLVGGESSDKRYPGPSVPEANTLLREHLAIPGGEVGNICIPSRRGEVERLQHKLRSGAT
FFTTQVLFHAEEITALLDALGERMEEGTRAPAFLVSLAPVRSERNIRFLRWLGVSLSHEL
EAWLTADEAAVTERSLSHLHETWRHIVDHAITRHSPCSLGVNIAPIGRIPSATTVALGRA
LRDVTP
>A0A7V8DVL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MNLPIAAASAKPVSVSFEFFPPKTEKMQETLWECVKRLEPLAPSFVSVTYGAGGTTRERT
HDTVVRIARESSLKPAAHLTCVGHSQGEVDDIARRYWDEGIRHIVALRGDAPEGSGAYQP
TPGGYAYAVDLVKGLKRINDFEISVAAYPEMHPDAPNPAFDLDNLKRKIDAGATRAISQY
FFDVDVYRRFMDRVRAAGITVPVLPGILPVTNFAQVQKFSAACGASVPGWMAKLFEGLDN
DPETRRLVAATVAAEQCRALAADGVTDFHFYTLNRADLAYAISHILGVRPKAE
>A0A5S5AZ10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosediminibacter litoriperuensis|TrEMBL
MQNRFKESLLDKNVFSVTWELVPGRGAREKTQEEAIMAAEQAARGGKIHALTLTDNPGGN
PAILADYIATEVIKKGIEPLVHFTCKDRNRNQIESQLYALDRAGVRNLLVMTGDYTVSGY
AGRPMPVFDVDPIHVLDLISKMNRGLEYQGIKGTIKHQPSDLFAGAVVSPFKATEAEQMV
QYFKLKKKIKAGAQFIVTQLGYDARKFHEVIQFIRQQGWNIPVVGNIYILPLGTARAMNK
NKIPGCVVTDKLVAELEKEAQAPDKGRQARLDRAAKMYAFMKGMGYDGVHIGGHNVKYED
VEYVIEKGEELSKNWLDFIHEFDFPIPGGFYYYEKDPKTSLNTPNPVDRKNRPLDAPVEF
IYRLSTFTHRLMLEPGTPLWKPMQAIARIVDGTSLERPYHAFEHLMKVCLYDCQNCGDCA
LMDVGYVCPMSQCPKNQRNGACGGSYMGWCEVYPNKKKCAYVRAYARLKRFGKEHELDGD
IIPPPDWNLHQTSSWLNYFLGRDHSAERMGIERYEKKKKDKK
>A0A1G0YW01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_52_8|TrEMBL
MEDKLKEMLCRQIVIFDGAMGTEIYRHNFFVNNSFEGLCLSSPDTISEIHKSYVDAGANV
LTTNTYSANFNKLARFGLGEKLCEINEAAVLLARKAAGENVLVAASVGPVGELSIELEDY
RGKSVAMLAEQIAVLEKAGADFIIFETLSSVQDTEFACAAISSGSNLPYVLSFSLDRNAE
TAKGETLGALLNVCAGAARPPTALGLNCGEGPEGMLNTLELLRSQVDYPIIVQPNAGVPK
NVDGRMIYMSSPEYLTTYALRYVNLGARGVGGCCGTGPEHIRDMARSVRPFAKSEFSSSI
KIKEPELPLKEPMPMAEKSAFAAKLAKREWVTSVEIVPPRGYQLAQTIEKARQCKAAGVD
AINLPDGPRASSRISPLITALKMQEEAGIEAVLHICCRDKNLIGMQADLLGCAAVGIRNI
LFITGDPPKLGDYPFASAVFDVDSIGMARIQDRMNRGVDVGGKPIDPPTCALIGVGADPN
AVDMQRELRRLREKAEAGAEFIITQPVFAVEPLLRFLDEIEDLKMPVLAGIWPLASYSNA
EFMKNEVPGVIVPDEVMRRMAQASGKEAQRQEGIKIAKESVAQLRGKICGVQVSAPFGNV
ATALAVLAP
>A0A7X4EQG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MADNRGRRQGRPGRRRRISGMAEKTMNGPVSANGLKSGGKLERVLAAGGFAVTCETSPTA
TTDLAPLLERVAPLKGVADAVNVTDGATAKAHVSSLVLAGAMMRQGIQPVLQFTVRDRNL
IALQGDLLGAGALGIPNILCLTGDDPKKGEEPDASPVFDLDSAGLMRLARRMRDDGLLNA
GREIKGPPKLFIGCADAPIAPKPGWEPKSLRAKIDAGADFAQTQYCFDLETAKTYFTRLA
DFGITEKLAFLVGIGPLASLRQAKWMDENLFGVSIPDAILKRLEGADDERAEGKKICAEL
IQQLREVPGVRGVHLMAPRQEAAMAEVIERSGVLEGRPALSA
>E8RS03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asticcacaulis excentricus (strain ATCC 15261 / DSM 4724 / KCTC 12464 / NCIMB 9791 / VKM B-1370 / CB 48)|TrEMBL
MAPPPAFVQSAIARSVRAGASHLNVSFEFFPPKSAEMEESLWGAIRRLEPLNPSFVSVTY
GAGGSTRERTHRTVKRILDETAMKPAAHLTCVEASREEVDEVIREYWNAGVRHIVALRGD
PPGGLQDGQYTPRPDGYQNATELTAAIRRIGDFEVSVGVYPEKHPQSPSLDFDLDVLRQK
VDAGATRGISQFFFEPETFLRFRDAVADAGIQIDLTPGIMPVTNFKGLRKMATACEAAVP
DWLQELFQGLDDDAETRKLLASAVAVEQVLGLEREGVNHFHFYTLNRAELVYSICRVLGL
RDSRTSAA
>A0A553FT40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium aurimucosum|TrEMBL
MSPRLSASAPLDQISEDTPKELKRTALSFEVIPPRHDADAAKIDRLLATLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTEKELEAWIDTLVDAGVRGLLALR
GDLPEGGMPAGHLPHADSLVRLIRRWESDRVARLAAGRLAVGVACYPKGHAESATPDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTKVLDQLAAATSPEEEKEIGMQITASLAKSVMNAGADGLHIYTHNNPDITTDLL
HRIGVIP
>A6LKZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosipho melanesiensis (strain DSM 12029 / CIP 104789 / BI429)|TrEMBL
MKISKIKDFFVSVEVIPPLRGHSIDEIYKVVDKIAPFNPAFISVTKHPAELEYYEVDGRI
LKLPKVRRPGTMGIVAALKMRYDIDVVPHLTCIGNSKFELEELLIDLDFIGIDNVFVVRG
DKKRNVIKKDGQYEYAYQLVEQIFNMNKGKYLYQNAKKTDFCIGVAGYPEKHFESPNMTE
DIKYLKRKIEAGAKFVITQMFFDEKKYIDFVERLKKENITIPIIPGIKPITSYKSAKKLP
GTFFIDIPEKLLEDLREAKTEKEEFFVGIRHTIKMIEKLREYGIPGIHIFTMSKPDPVLE
ILKNI
>A0A520NUJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTGRHSPKSLPAPVSDGRDLKVSFEFFPPKTEKMAETLWKSVQRLEPLSPRFVSVTYGAG
GSTRERTHSTVNRINTETSLSAAAHLTCVGATQEEVNAVAEAYWEAGIRHIVALRGDPPD
DEPYSPHPGGYGYAADLVRGLRDVADFEISVAAYPETHPQATSPSDDLDNLKRKLDAGAT
RAITQYFFDVGIYLDFLDRVRKSGIDVEIVPGILPVTNFAQVLRFSAMCGTKVPDWMEQL
FEGLDDDPETRRLVAATATAEQCRLLHSEGVEAFHFYTLNRADLSFAICHILGVRPHGSS
A
>A0A2E8T7R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MRIKLGHLSNIQGTEVYLSKGSFIEKESISVSFEFFPPSSEKLEKQLWESVLLLAPLKPS
FVSVTYGAGGNTRQRTFNTVKRIVTETPLIPAAHLTCIGSTSESLQVAAKEYWDVGVRHL
VALRGDPEQKTGKFIPHPKGYKNAGELVRGLKEVADFEISVAAYPEVHPEAQSADSDLDN
LAYKLDCGASRAITQFFFDIDVFLRFRDAATARGINAPIVPGILPVTNIKRLIQFANHCK
TSIPNWLKDMLNGLDKDPNSRRLIAGWIAIEQCRQLARHGVTEFHFYTLNRAELTRAICH
ALGVRDQERLEST
>N9RVB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 2100|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKTVHQELQLLNPEFFSITYGAGGSTRERTLAAIHDFN
GKGTPVAPHLSCIGDNKTRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIRQHSGDHFHIEVAAYPEMHPQADTFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVDIPVAPGIMPITNASNLIRFADGTGAEVPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A2I0SAW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces populi|TrEMBL
MTTFSFEFFPPKTARGEDTLWKAIRRIEPLRPDFVSVTYGAGGSSRDRTVAVTRRIAAET
TLRPVAHLTAVGHSVAELRHIIGQYADAGIRDVLVLRGDPPGDPKGPWTPHPQGLRYAYE
LVELVRSLGDFRIGVAAFPERHPRSGDWDQDIRHFVAKCRAGADYAITQMFFRVGDYLRL
RDRVEAAGCDIPIIPEIMPATDHRQIARFAELSDAAFPAGLAARLYTARGDAAAGHRIGV
EYATAMADSLLAEGAPGLHYITLNKSTAALDIHRNVLASSSTRILNVC
>A0A4P6H9K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. Pch-S|TrEMBL
MSPRPPQRDENPAGIHLPLEPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNR
AKVFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPVMQIACRDKNRIAIQGDVLGG
AAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQV
FLGAAINPFAPPYDFRPIHLGKKIAAGAQFVQSQYCFDVPMFRTFMQKASDLGLTEKVFV
LVGVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAEDQKKEGKNLCIDIINEVKEIPGV
SGVHVMAYRQEEYVAEIVDESGVLKGRRPWKREVRPDDALVAERLGHILHDDVTETQVDM
VKTAH
>A0A379B4X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Pasteurella] mairii|TrEMBL
MSYAKEMDTLNQHLVDLKGDINVSFEFFPPKNEKMETILWESIHRLKSLEPKFVSVTYGA
NSG
>A0A2E7RAW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MMVKPKVSFEFFPPASEKMAEMLWLAVERLAPLDPTFVSVTYGAGGSTRERTHSTVKRLR
DETSLEPAAHLTCVGATKTEIDGIIRSYWDSGVRHIVALRGDTQGDNGKYQPHPNGYANG
AELTKGIKNIADFFISVSAYPEKHPDSASRSADIEMLKQKVDAGAGQAITQFFFEPEYFF
RYRDAVAAAGVSIPLIPGIIPVINFKRIQSFAATCGTKIPDWMIERFEGLEDDPQTRKMV
AATIAAETCQKLAAGGVEQYHFYTLNQADLTYAICHILGLRPSAAGF
>G2KV61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructilactobacillus sanfranciscensis (strain TMW 1.1304)|TrEMBL
MYHSAKEKALSCFKEAIHPTLVEVGVFSPIMDKKPVGDFKRASELVKFIKEHGKFNIAGA
CYPQKHPESINFVDDILHLKEKVNQGVSYLITQTLFDNQAFYDFRERLQFSQVDVPIEVG
IMPCTNLNQIKKITELSGNPMPKKFVDIMDHFRNNQEAMRDAGINYAIEQIVDLLSNNSD
GIHLYTMNNAENDQQIRDTTHTLFAETSNHPTERV
>A0A1R0Z2N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus odorifer|TrEMBL
MKPDLRSAWGNKVLVGDGAMGTYLYQKGFPVGISYEELNLTSPGVIEDVHRSYIEAGAVL
LESNTFSANYDRLSKYGLESKVEEINRAGVRIARRAAGDHGYVLGAVGSIRAGKRANLSS
TELKKYFTQQIAALLEEDVDGIMLETFYDVEELHLALRTLRKISSLPVVCQLAVDETART
LDGLTLPEAFRILEGDGADVIGFNCNTGPNGMKRALKAVQGSLVLPASVYPNAGVADYVD
GEYRYGASPEYFGQMAQTFAEMGCRIIGGCCGTTPQHIAEISSALKNYVPQPLAQPLPPT
VERVSLQDNFGDDDREGREPNLVDLVKERHTVIVELDPPRELDITKFMQGAEALRRAGAD
ALTLADNSLAVTRMSNMALGHLVHAKTGLRPLVHIACRDRNLIGTQSHLMGFDALGIDHV
LAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGISFSGKPLKQKANFVIGAAFNPN
VKHLDKAVQRLEKKIASGADYIMTQPVYDQELIVKIAEATAHLEIPVFIGVMPLASGRNA
EFLHNEVPGIQLTDDVRNRMKGLEGEAGRAEGVAIAKELLDVATAHFNGIYLMTPFMFYD
MSAQLMEYVWEKSGRKLSPLFR
>A0A8C1QTU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGKDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIITQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQFESPLFAQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDND
AAIRNYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAV
SAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSK
SPKEALLQMWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDEL
EKVNRRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKK
YEPRVNYHIVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALW
IEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQK
D
>A0A182SU16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles maculatus|TrEMBL
MDATNSITEELNEGVLHKKLDRIFSSPSAPTVCYSIEIAAKDDFDIELLERLTPQPVFCS
LPWISDDNLRYSDDFLRSPTMQLADKLCKAHYTVVNHVSCYNITEQQVDRLLTSGVKNLF
VIRGDTVQEDQIFQHSAGLVQYLRKQQQQERSLPRLTIGVGGYPYGHHQSPSQTEELNYL
KEKIDHGVDFLLTQTLYDSGAFFRYRNRCRQAGITIPIIPGIYLPHSYRHLQAMLNLTRI
SLTPEVHAAFAAHAQDLPEQFEAFVVDHFVGVLRELLEPNQTGSSDPIKLVHFFSFNKFP
LIQKMLRKMDDFFH
>A0A7U4E8T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Runella slithyformis (strain ATCC 29530 / DSM 19594 / LMG 11500 / NCIMB 11436 / LSU 4)|TrEMBL
MTKITDYIRQANGKTLFSLEVIPPLKGSNIKELLANIEPLMDFKPPFIDVTYHREEYIEQ
ALPDGSIKRIVTRKRPGTLGICSSIMHKFGVDAVPHVLCGGFSREETEDFLMDLHYLGID
NVLVLRGDPAKPYKTFKPKTNGHQFAGQLVEQVANMNKGQYLHEGVDPLEPTDFCIGVAA
YPEKHFEAVDFDVDFDYLKQKIALGADYMVTQMFFDNQKYFQFVKRCREAGITIPIIPGL
KPLSTKKQLSILPRIFYLEMPEEFVKSVEACENDTQAKQVGIEWCTQQCKELMDFGVPVL
HFYTMGKSENIYKIASQLY
>A0A8C2CCS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MLFCPTPMYLFWLDLFENDVNSHYRCAEMKVFCSLCVRFDRMGSGGPLFIDVTWHPAGDP
GSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPI
GEDWVEEDGGFNYATDLVKHIRCECDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAG
AHFIVTQLFFRAETFLKFVKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIM
QVIEPIKDNDAAIRSYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAE
DPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELT
DYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLA
PETNLLKDELEKVNCRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSEN
VTALLQVLKKYEPRVNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFM
YWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFT
LLDSPPETQEEGSQS
>A0A257USE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 37-71-11|TrEMBL
MRARARGRPGPHPATRGTGKQDSLHAVEEQGARPSGMPLAKTNLYNAEMDHARTVRRFAD
HVVVADGAMGSELLTRVPAGVHLDLAPLDYPRQVLEIHLAYLAAGAELIETATFAASRPR
LERLQAGDRVEALNSAGVKLAREAREIAGVDCLIAGSIGPLAGVIDLDERAGRSAIAGAH
AEQAAILAGRGADLLILETFFRLDELLLAIEAARGATDLPLVAMLTFPFERLPESHPELA
AQVRELLACDVLAAGVNCAPGPQGTLDIVECLADASRPLAVMPNAGSLVRRDGRIFFPPA
TPSYLAGFARRAAELGAGLVGGCCGTGPEHIRAMADAVRGMSPAHAHRAPVAVEERRVPA
PLPHPRPASSLAAKLAEGRFVRVVQLDPPRGTNSERIIEATRALAASGRVDAFDINSNPL
ARLRMESLWLGAEIQRATGIETVPHITPRDASLMGLQAQLLGAWHAGIRNLLAISGDPSQ
LGDYPGVHDVNHVDIFELVRSVARMAEGFDCAGNPIGEPPAYCLGVAVNPAADDLGHEVE
RLRRKADAGAHFAMTQVFFSWEPWERLLDRCGGALPLPALVAVWPLPSFRLALRLHNEVP
GIHVPEELLARLEAAGPDAGKVGTERALAMLAEAPRRAAGVYLVAPFKNPADVLGLLES
>A0A2I2A644|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenovibrio sp. SC-1|TrEMBL
MHSQQKYPQHLSLEFFPPRTDAGMEKLKTVIESLKVIDPQYMSVTYGAGGTTQARTLETV
DYIQTQTEFDAAPHLTCIGATAESVRDLLDTYTQMGIKRIVALRGDLPSGMMDPGEFKYA
SDLIAFIRQERGDQFHLEVAAYPETHPQARNCDIGIKWFKHKIAQGADSAITQYFYNVDS
YLYFIDNCERSGIDLPIVPGIMPITNYENLIRFSEGCGAEVPRWLKCRLESYENDTASLQ
AFGQDVVTDLCQRLLDAGAPGLHFYSMNQAEPTTHIVQALTFKSPSE
>F0IPY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis SK150|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLQIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>G4Q6E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidaminococcus intestini (strain RyC-MR95)|TrEMBL
MKIKELLDSPKVTISCELFPPKKGTELQNAMDIVHAIAIDGVDYMSVTYGAGGTAVGKSL
AIASEVERSGVPALAHLTCIGAKKDGIARVLRDMKAGGIDNVLALRGDRPQGMDELPESD
FPHASDLVRFIKETGDFCVGCATYPEGHPESRTLDEDLENMKRKVDAGCDFLVTQMFFDN
EMFYNFMYRLLAKGVRVPVVAGVMPITNAKQVERIFTLSGTPIPSKLRAVVERFGDHPEA
LRQAGMAYTTGQIMDLIANGFNHIHVYTMNKPEVIGGIRRTLSEVIKL
>A0A514ZSG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma sp. KCTC 42546|TrEMBL
MFLEKIKSGESGVLLYGITPPKAGTAPERVAEIAQKTIERLTALDIDALVVYDVQDESAR
TTEERPFPFINALDPLVFAAGYLGTLTIPKIIYRPAGKFSNVELSDWLEELHDHNFYPVF
VGVPAPDYPVKTSLPEAYRLWSKHQNTSVIGAVTIPERHNVLNDEDVRMLDKMNCGVSYF
ISQCVFNLDYAKQVIEDLTIRCNTQQVKAPTIIFTITACGSTKTLHFMEWLGIHVPDELK
EDLKKSDDILEKSVQICLDIATELTTFCMERSIPFGFNIESVAIRKAEIEASIYLANQIG
QMLTDKGVRNPSEGKGLELTSGKQNTPDTWVIKDI
>A0A3M0ZB78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MPIREKLGRETLFSFEFFPPKTAAGVRSLMRSIHKLETFSPSFVSVTMGAGGTDLQQKRT
RDTVMRIHKETSLTIMPHLTAIGKRKEEVRSELDAFAAQGVTNIFALRGDYPAGDNGQAI
RERTELHYANELVAFIREHYGDHFSIGVAGYPEGHPETPSKLQDLYNLKRKIDAGAEFII
TQLFFDNREFFDFRDRCQLIGIDVPIIAGIMPILSRQGILRMCDLCGARIPASLLRQIFD
ASDDDVAQIGIEWAYRQCEELLREEVAGLHFYTLNKSKATCKIFTRLRQNKACSCNGECE
>A0A3R5ZVB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia inulinivorans|TrEMBL
MRLTELLNKDEVTISCELFPPKQGAQLENYKNIVKDMAALKPAYMSVTYGATGGTSDYTV
KLAEEVRNNNIPALAHLTCASSTREKVASVIEELKAANIENILALRGDIPANADFPLPDQ
YKHASELIADIKAQGDFCIGGACYPEGHPEAATIFEDLDHLKEKVDAGCEFLTTQMFFDN
NILYNFMYKTLKKGIDVPIVAGIMPVTNASQIKRITSLSGNMVPPRFLAIVDRFGDNPAA
MRQAGIAYATEQIIDLIANGVNHVHIYTMNKPDVAGEILDNLSNIYVR
>D7AQ59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter mathranii subsp. mathranii (strain DSM 11426 / CCUG 53645 / CIP 108742 / A3)|TrEMBL
MLKNENLCNKLKKRKFVVTAEISTPKGVDVTKTIEKARKLKGIVDALNITDSPMANMRMS
PIAVAHLLQDHLSIEAIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDDPSHGDTPQ
AKGVYDVDSIGLLKIISAFNKGYDYNGNKLDSPTEFCAGTTANPNDLRDEAIEKLKVKIE
AGAEFIQTQPVYDEEILFKFIEKIKDLNVPLLVGILPLKSFKMAVNLNEKVPGIDIPEKV
LERLKDGGKEEGINIAVEFIKNVRSEVAGIHIMPLGNTDVVLEIISRIDDLACEVIQNKV
QMN
>A0A660VRU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MADRAPFLEALRERVILGDGGMGSEIYGRGIFINRCYDELNLSARELVQGIHADFIKAGS
DLIETNTYGANRPKLAAYGLEDKLLDLLREGVSLAREVAGERVYVAGSVGPLGPAASEAG
LSESERDAAYREVAVALAEAGADLVFLDTFTSMPDLRLAIEACKAVTDLPVVGSFSFHRG
FVMGSHDFLVPPDDVARAAIRAGVDVIGANCGDGPHTTLDVLEIMTQVTGDVPVAAMPNV
GGPALIEGRSVYLSSPEYMAEYSRRFFQIGARLIGGCCGVTPTQVREARSFLASVQPRTA
HVKIDDHGHRTRGKAPTPLAERSAWGAGLGQRFMVSVELDPPKGLDASVSVEKARFLHDQ
GIDAVNIADGPRAMARMNPTSLAVLVKQAVGMETIIHYCCRDRNVLGMQMDLIGAHSLGL
RNLMLITGDPPKMGNFPDATAVFDVDSIGLIGFADRLNHGFDLSGEPINKKGDDATDFVI
GTGCNPGALDIGLEADRLRRKIEAGAEYVFSQPIYDSTKLERFLDACKGFLSIPFFVGIL
PLASLKNAEFLTANVPGMDVPDAIMQRLRDAKSRDEQRAVGIHVATDSLAHAADLPPVQG
TYVFPPFGKYEAILQVLKDAGVRE
>A0A7Z9Y4B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
RLAPLGRVKRHEARAAFREQIEALVTAGVDLLALETISDLWEMEEAVKAARAIAPDIPIV
AMMTFTRDDLTLLGNRPDAVARRLAGLDVDVIGVNCSGGPAQVLRITMMMRQVSPDALLA
ASPNAGWPEASAEGRVFYPATPDYYGKYAVGLAEAGACIVGGCCGTTEEHIAAMRLALDT
PDYAGVELPQVRVAEREDKGTAVPDEPTQLAQFLADGTFVITVEMRPPRGVSPHRLLRGA
HMLKEAGANILNIADTPVAQMRMSAWAAAHLVQKEVGLETILHFPTRGRNLLRVQGDLLA
AYAMNIRNLFVTMGDPTRIGDYPEAMDSYDIVPTGLIQLIKKQFNAGVDKAGQEIDRATN
FVVGCALSLTPHDVGREMKLLRKKMRNGADFALTQPIFDLQAARNFVDRYEAAYGEPLLP
LIAGMYPLYNGRNAEFLHNEVPGIIIPEAIRRRMRQAEDSQREGVRIAAEILAEIRPFTA
GVYMMPAFSRYDLVADVLDELT
>A0A7K3GE16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5770|TrEMBL
MALGTASVRSDRARTVRDILASGGTSYSFEFYAPRTEKGEQSLWKAMRRVEAVGPSFVSV
TYGAGGTTRGGTVKATQKIASDSTLTPVAHLTAVGQSVAELRNILGQYADAGIRNMLALR
GDPPGDPLGEWIEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSAVKAGCETPIIPEVMPVVNVKTLDRLPQLSNAAF
PARVKDRILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A7Z9S197|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
ATMEWEAAGSTILEVVPPTLDSGLEGLYSRISRVRRLVSDGDFDAVNIPEIHDEENRNDQ
GIRTRQYSPRMQPRELGRRIQDELGLPVIINHVVSFKPIGALMDWIRETVAGYGIRNIVL
VGAPHERKPWPGPPVPEANAAIRTEFGKESLKIGNICIPGREGSPIPESVRMEQKALSGA
DFFTTQIIYDPTEIIELRHQMVREASPARYCPILVSLCPVRRHRNLAFLRYLGVKIPDAL
EQELHALGEPECLERSLEILRSIQSDLIEAQGDPADVAPLGWNIAPVGQIPTASIRDLMA
RLSGSVRS
>A0A1B9APC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. FJAT-27225|TrEMBL
MTFLEKLQTQILIADGAMGTLLYSYGSDSCFEELNLSHPEQIQNIHKAYIAAGADVIQTN
TYAANYLKLQRYGLEDSVKEINSAAVRNAKKAAQDHNFVLGTMGGNRGVKPQSVSIEEIK
RSFREQLYCLLLEGVDGLLLETFYDLEELETVLSIARKETALPIIAQVSLQEAGVLQDRT
PINEAMNRLDGLGADVVGLNCRLGPHHMLVTLEQIELPSHAFLSAYPNASLPAYTDGKFH
YEGDAEYFRKSARQFRTEGIRLLGGCCGTTPAHIKAFAEELKNAAPITEKTVNVKTGPLV
IEPRQTIPDYPPLQDVVKERPSVIVELDPPRKLDTTKFFEGAKALKKAGIDALTLADNSL
ASVRISNESLGYLVKQELSMRPLIHIACRDRNIIGLQSHLMGLHTLGLHDVLAVTGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNEGLSYSGKDLGQKTAFSIGAAFNPNVRSLEKAVN
RLEKKIDHGADYFISQPVFSEEKLIEVHEHTKHLESPIYIGLMPLLNTKNTEFLHNEVPG
IKISQEIRDRMAALADNPVQAAQEGLAITKSLIDAALELFNGIYLITPFLRYELTVELAN
YARLRAQEKRRSIYATTHIH
>A0A354T6X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MSDFLAALSSRPLLSDGAMGSYLFTLTGRLSEANHVYEAFNLDRPELVRQVHRDYLAAGA
RGLKTNTFGANFAQLRQFGLQDRVDEINRAGVRLVREEITAAQPAEPVFVLGSMGPTAEE
LDTALAVADAYHAQVDALIAAGADALLLETFGSLKQLELLIALIKSRPGAPPIIANLALR
PDDKVRVPENDPKDFVRHMADLGVAVAGVNCCAPWDATAFVEAVADTEPVRAGRILLAAM
PNAGGFQRVGNRFMTTVNPEAAGKLARSLADRGVRLLGGCCEMHPPHIAEMRNYLATRGA
GAGITTAARAATLAPCGEAEKADNGRFSRKLKAGEFVVSVEAMPPRGTDDAVVRRKVELV
AQLAASGLVDAVDFTDGSRGIPLIPPGDFIQLVRTRLRWTAETGDAVEFIPHFTGRDLNV
MGVQSRLLGYHANRIHNVLFVTGDPPKMSPTYPRSTAVFDLDSVAMIRLTHTCLNAGVDF
GGAPLGRHADPRMHFTIGSGVEPEAPDLPRELDRLRRKIDHGADYIMTQPAFRSEPLAAL
EPLRDRCAFLVGVMVLSNLEHARRMAQVPGVVVPDAMLQRFAAYADVADQNKLGQELAAA
QIREIVSEGWAGVYLMSTSAGAGTLDILKAGLGR
>A0A7W1J024|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRLDQLFAAKARTLSFEFFPPKNERSWLTLEDTIDQLAPLGPDFVSVTYGAGGGTRAKTR
EIVEHIQAKTGIAAMAHLTCVNATKADLQALLNEYATAGIGNLLALRGDPPKGETRFTPT
DGGCAYALDLINLIRADGRFAITCAAFPEKHPDAVSREADWANLEHKLKAGASAAITQCF
FTVEPYIELIAHLTTRLGYAPRIIPGILPITNFKSLERFCATCGATIPQTLRAQLAPLAD
DAVAVRRAGIAYTVQFCKALLAAGAPGLHLYALNRSTAVAEVVTALRLSGHLD
>A0A7C3LNG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospiraceae bacterium|TrEMBL
MRLIKDIYKDNDKKRNIFSFEFFPPKNAEGEAKLFATIEELKSLAPDFISVTYGAGGSTR
SKTKEWVTAIQDRYQITAMAHFTCVGSGREESYQIVKELYDSGVQNIMALRGDPPKGEVA
FKPSVDGFRYAGELISFLKEKLPNLSYGGGCYPEKHPEAISLDQDLLHLKMKQDKGSDFF
ITQLFFDNKVFKSFMDKCRAKGINKPIIPGIMPITQYSQIERFTQMAGCSFPRELVSGIE
QYKDDKEKLISFSIDFTVSQCRELLRDLGAPGIHFYTLNQSMATREILKKLK
>A0A7W1GDT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrinomonadaceae bacterium|TrEMBL
METFKELLDSDHITVFDGAMGTMLYAKGVYINRSYDELNITNPDLVREVHEEYARAGAEV
LETNTFGATTYHLQQYGLEGSLRQINIAAARLAREAAADRCYVAGAVGPLGLRIEPYGPT
SFDEAKDMFKEQVAALLEGGVDLFVLETFSDVSEIRQAIRAVRELCDLPLIAHMTILTDG
NTSFGTTPQVFTARLDEWGADVIGLNCGVGPSTILSAVEKMRGLTTKKLAVQPNAGLPRD
VQGRQFYMCSPEYMAKYSKRLIQAGVKFIGGCCGTTPAHIKLISDAVRAVSPRIHRGAAV
EVTRPARVEELTPVDIRVVPLAERSNWARRLVAGEFVTTVEVLPPKGCDAAKTLDQIRLL
KDAGVNAVNIPDGPRAQTRMSAQATALLVERDIGLESVLHYCCRDRNLLGMMSDLLGAAA
LGLRNLLLITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGCPTSFCIG
VGVNPGAINLDEELRRFEFKVEAGAEFAITQPVFDIDQLSEFLKRIEHVKIPIVAGIWPL
VSYRNAEFLHNEVPGVRVTQSIMERMRVASDKGKDAAREEGLQIARESLLQVRDLIQGVQ
VSAPFNNVRYALEVFDALDEFRDRRLNAPKAIQEPVVAAS
>A0A7Z7J4I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. phaseoli|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A7C3PP41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPGFTPGRRWQPAYSPFQKETFGDRALQVLEYSIKGPLFGCRMCGNCLLQETALICPMEC
PKGLRNGPCGGSTAEYCYVDKSRPCIWYKIYERSFKYGREELLLEVLPPLDWELVGRDSW
GAIFRNIQKMGVGKVLRGLVSKETRTETWDGIFRPVRQPDWWKGDSLYHPPAYTEPASEL
ERRLAAGEFVVTSEITPPLSSATDRLIRNIKATAPLVAAVNFTDNQSATPRMTSWACSTV
AIQQGAEPVLQMSARNRSRGSLQSEIIGATALGVRNVLCVTGDSAKLSPSPRDNMQINDL
DAVQMLWVLRRMRDEGKYLDGREIKNPPKFFLGAAASPFSSNPKFQALREQKKVNAGAQF
FQTNLIFNVDGMEVWLNELAKRNILDKVYILAGVTPIKSFKMAQRLAEVPGVHLPQEVLQ
RMEIADKSGNAQEEGVQIALEIIGRIKAYRNQGIHGIHLMPVGWDEIVPRIVTEAGLIPE
QNVVQELVPAH
>A0A8G0I0R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. sptzw28|TrEMBL
MKPDLREALGARILTGDGAMGTYLYQMGFPVGVSYEEFNLLRPNVIEDVHRRYYEAGARV
IETNTFSANHESLSRYGLDADVAAINRAGVQIARNAVGSDAYVVGAVGSIRAGKRRNISS
SQLKHSFQQQIDALLNEGVDGLLLETFYDLEEMLIALKVTRKQSNIPVICQFAVEKEAVT
QDGHPLAFAFERLREEGADVAGFNCRSGPNGILRAIDSIQGDVALPLSVFPNAGIPDYVD
GKYMFTATPEYFAQSARKFADRGARIIGGCCGTTPEHIAAIAEALNGYVPQPGAVEPYEP
PAVEHTAVTASSQQVTGLGEPAAPAAAEPTIVDLVRERHTVIVELDPPRDLDIRKFMAGS
AALKEAGADAVTMADNSLAMTRMSNLALASLVQHQVGLRPLVHIACRDRNLIGTQSHMMG
LDALSIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNDGISFSGKPLKQKAKF
IVGAAFNPNVKYLDKAIARLERKVESGADYIMTQPVYSSDLIVKIAEATKHLSIPVFIGI
MPLASGRNAEYLHNEVPGIQLSDDVRSRMAGLEGEAGRSEGVRIAEELLDTALKHFNGIY
LITPFLSYDMTVRLTKYVWEKTKK
>A0A7X9AZL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oligosphaeraceae bacterium|TrEMBL
MPQEAKQIDMSFAGDQRLENSMLKGEFHYFLECDSPRSQQPFNASLALFKELGQAFRQQE
QLHGWLLTDRLLSEHCHDPVMLAEALTAASDKPVIMTVSGRGSDLERCKSVLAEGKATGR
RDFLAVSGDLSDLEDTSANKPYTDSVNILHSARSQGKDLRLGAVVNPFKYTPEDQSLQYA
KMLRKINSGAQFLIAQAGWDMKKAQELQWFLQRMNLPITVIARVCVFELEEAKALANGYK
TGVYVPIPLACLIQQDAEKSQEEFTDLQLQRTAWQVLGYKRLGYAAVLLSGIRNPKNWKK
LLQYMEELEKQYPDYDSWLELWKKQYGELNFVPGQNPHFLYHGLLQQGKRDFDPEEDPVQ
GSALPKPTWLDRWRYWLGRKLDKPGKEGKFWDLLRRLCRLPKGKLQELRPCLYLNNAPCP
KKLRWGACGNAGSDGLCENGQQRCFFHRILHLAAHANNYQALESAAE
>A0A3M1MGR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MQLNELYTDGRLVLSFELFPPKTDGGMETLMRSVHRLNSHRPDFFTCTYGAGGSTRARTL
EVASRIRRELQIPVASHLTCVGSTRDQLRDYLQAARQAGIDYIVALRGDPPQGQDRFTAI
AGGLRYANELVELIRAEFPEFGILVAGYPEVHVEAPSPDVDLQNLVRKVHAGADVVVTQL
FYDNEDFLRFRDRCQAAGIRIPIVPGLLPVLSLKQVQRITSLCGAKLPPRLVELLSERDD
PDWQFNVGVEHAIAQTEGLIEAGVPGLHYYVLNRSDAFDRIVQAVPHLSRS
>A0A285SUK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio ruminis DSM 9787|TrEMBL
MFKDMFANDSSLSFEVFPPKKDDEFENCYKVLDSLSELKPDFISVTYGAGGSRSKKTVEI
ASYIQNELHTDAMAHMTCVGSTSEDILAVTRDLEAVGVNHVLALRGDKPRDMSDEQFNKR
VFPHATDLIRFLNENTKLDISASCYPEKHPEAMSMDSDLAFMKMKQDMGAKMFISQLFFD
NADFYRFTERADKTGITIPIVAGIMPITSAKQIGSTVTLAGSSVPKKLADICARYGESPD
DMRKAGIEYAIDQIRDLRKCGVGHIHIYCMNKPKMTAEICKSI
>A0A142IMH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas alcaligenes|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMGVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVGVPTAPHLSCVGDSKDELRSLLSQYKNSGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRNETGDHFHIEVAAYPEVHPQARSYEDDLQNFVRKCRAGANSAITQYFFSADCYFY
FVERVRKLGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDLDSIQAFG
EQVVTEMCERLLQGGAPGLHFYTLNQADASLAIWNNLKLPR
>A0A0S2ZS57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. polymorphum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPIDRELEIGD
FNYAKDLINYIHEKKEDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A2E5X3Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRIGDLYARDSAPVFSFEFFPPKTDGGAANLMETVGDLKEALAPDWVSVTYGAGGATRGR
TLEVVSRIQSDLELTAMAHQTCVAASRAEVQANVERLAAAGIENILALRGDMPAEEGFVP
PTDGFGYATDLLEFLGQRFDLCLGAACYPETHPEAESAEADLHWTRRKQELGAGFLITQI
FFDNRHYLDFVARARQAGVSVPIVPGIMPITDVAQIERFTEMCGSEIPEELTARLRRHAD
DPAVVMATGIEHAITQCRELLAAGAPGVHFYTLNKSHATRSILAALRG
>A0A3D6D324|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
SGIKNILALRGDPPGGKGDFQATEGGFTYSKDLVAFIRSEFDFSIGVAGFPEGHIACKEG
REVDWDRLKEKVDSGADFIITQLFFDNDDFFRFRDHLVKKTGMTKPIIPGILSVLSTRQI
KRFTELCGASIPESMLNRLDDLAEDDAAATEFGIEHAVRQCEALLDAGVPGLHFYCLNKS
YSTNRIVDALSRYR
>A0A3M6TDV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pocillopora damicornis|TrEMBL
PKSEKIMSQQASERESKPEKLIDTIRHKIEKNEQFFSLEFYPPKTFNGATNLMAILGRLH
EQCTPLFCDITWKPSQDPMSDKCQSEPSTLLVSAAMIDVYGQNIMIHIPSGNTTRSQVLE
HLNRAKNLGIKSVLAVRGDESYGEAMTPKEDGFDYTVDLVKFIKSEFGDHFTIGVVGYLM
ASSDVHSYEEDLKHLKAEVDAGADLIITQMFFEVKTFLKFVDDCQRYGINVPIIPALFPI
QNFNSLRQLKRQSRVEIPQWLLDKLAPMKDDTTAVMNYGIKYSTEMCKQLFESGHVHGVH
FYTLNRETSITEILEKIGMSHKEDELDSVSMRRLPWMPSPAQARRGQMELVRPIFWTSRP
RSYMIRTSNWDEFPNGRWGDSSAASFGELKDYHLVLLGTNKSKEELLNMWGRELNSPEDV
FEVFVCYLNGNENRHGHGILTINSQPNVNGAPSTDPVSGWGRPGGYVFQKVNSADWLSLN
ELKAYLEFFTSEEIAMCLHEVLQDYPTVNYHIVNFSGKEDVTNANVYSSNAVTWGVFPGS
EILQPTVVDPIAFQFWKDEAFALWKHQWGHIYPDKSRSRGIIDTIHDTYYLINLVDNDYV
AGNILFDILDIVLKKLGKI
>A0A3A0E293|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MTIRHAYGPGRLGLSFELFPPKTAEGMTSLFEHVDQLVAFRPSYITCTFGAGGSTQDRTL
EVIAGVRDKYQLPVATHLTCVGLTPPRIREYLARAVDLGIENVVALRGDPPRGEAAFRPV
DGGFSYANELVAFIRREFPAMGIAVGGYPEKHLEAPSFQVDLENLKRKVDAGADVVITQL
FYDNDDFFRFRDRCRQLGIEQPIVPGLLPVTNGSQIQRIASLCGAKLPPAFSAALEKHAS
DPAGQFEVGVEFATRQAEGLLAAGAPGIHFYVLNKSEATRRVLTALPHHFARSSEPPTRA
>A0A372ZP41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora xanthocidica|TrEMBL
MTLGKPSTRTDRAATVRDLLATGKRSYSFEFMPPRNAEAEAGLWNAIRRLEALSPTFVSV
TYGAGGSTRERTVNVTGRIAQETTLTPAAHLTAVGHSVGELRNILGHYADQGVRNILALR
GDPPGDPLGAWVRHPGGVEYAADLVHLIKDSGDFCVGVAAFPEMHPRSPDWESEIRHFVT
KCRSGADYAITQMFFEVDGYLRFRDRLQKSGCDIPVIPEIMPVTSIRSLRRIPTLSTATI
PTALSDRMLEHQNDPAAVRSIGIEHATAMCRRLLSEGVPGLHFMTMNFSTVTTEIYQNLG
LPRSG
>A0A2U2S4M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MNIAHILAQPGTHFSFEFFPPKTPEASQTLFEAIERLSPLHPSFVSVTYGANGSTRDLTR
DLVIRLRHQTSLNVVAHITAVGASRSQIHALLEEYAQAGIENLMVLRGDPPKDVPNYSPP
ADGFRYAADLVAYIKKHFPHMGIGVAGFPEGHPETPNRLLEMEYLKAKVDCGADYICTQL
FFDNRDFYDFCERCEIAGIRVPILAGIMPITSLSGLRRMSELALGSRIPAKLLRAIHRAE
DDRAIERIGIHWTTEQVFDLYDQNVKGIHFYTLNRSCPTLKVYEILGKSLGENWSVP
>A0A366IEU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium celere|TrEMBL
MSITTAPVTVPGLRLSASAPACAPDPPAPRHRLRRALSFEVIPPRSPAQAAAMPEFLRNL
DSLSPDYLAVTSSATSGWLHGTADFIRFVAEHTSLRPLAHLACTAGTEAELASWVDHLLG
VGVRGFLAIRGDFPPGASSVPTGHLAHADALVDLLRRIEAENAARLAAGRLGIGVAAYPS
GHPESTGPDEDLDVLAAKQRNGADFAITQLFFDPGAYARLRRRAEHAGIRIPIIPGILPI
TSIRRLRTMARLARLAIPDELLRRFDGASSEESIRRVGLEITAEHTAAILDSGADGLHFY
TFNDQTTTFELLDALDTAGVTLGSLQPRAR
>A0A357IXC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospiraceae bacterium|TrEMBL
MKKIAEILKEEAGKRPVFSFEFFPPKKPEGEQTLMNTIQRLKSLDPDFVSVTYGAGGSTR
EKTRQWVRDIQDKHDITAMAHYTCVGHGKDEILSNLKDLYSDGIRNIMALRGDPPKGEKN
FTPPEDGFAYGSELIEYIKSTGMDFSLGGGGYPETHQEAASPEQDLQNLKKKVDAGAEFI
VTQLFFRNDHYFRYVKQCREVGITVPIIPGIMPITSFGQIQKFTEMAGCEIPNELTEDIK
ACGEDRGRLLEVSLGYSIRQCRDLLKGGAPGIHFYTLNQSQATSTILKAIN
>A0A3M1ZLP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium|TrEMBL
QIERFSRMCGASIPAWLHERMDPIRNDLDRVFEAGIELASRQCEELIERGVPGLHFYTLN
KSAATIAIVRALGLHRTR
>A0A4Q5TYS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIDHINQAKGTLVSFEVLPPLKGKGIEALYKHLDPLMAHKPAFINVTYHRSEHVYKKK
ADGNFEKVIVRKRPGTESICAAIMNKYDVDTVPHLICGGFSINDTEDALLNLQYLGIDNV
LVLRGDAAKNETTFEPEPGGHKFASDLIRQVVNLNAGVYLEEDLKATNKTTFCIGVAGYP
EKHFEAPNMKTDLAYLKAKVDGGADYIVTQMFFDNEKYYQFVRDCREAGITVPVIPGLKP
IYNRKQLNMLPKTFHIDLPADLANEVAKCRTDEDVELVGQEWLLMQSRDLKKNNVPVLHY
YTLGKPHVVSNVVSQL
>A0A3B9C111|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTEHIKAAQGKTLFSFEILPPVKGKSIDSIFTVLDPLMEFKPSFINVTYHRSEQVYKK
KSDGSFDLIDIRKRPGTVGICAALMNHYKIDAVPHLICGGFSKDETENALIDLNFLGIDN
VLALRGDPPKNTKYFQSHPQGHHYAIDLVKQIEKLNRGIYVEEEISVGGKTDFCIGVAGY
PEKHYESPNPDLDLMHLKSKIDAGADYITTQMFFDNQKYHQFVDRCRQMDILAPIIPGLT
TITSMKQLSGIPSIFHVDIPSDLAVELIKCKNEKDAEKVGTEWLIMQTKDLISSGAPVIH
FYTLGKPQVVYNVMKAMV
>A0A3M2EKF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium|TrEMBL
MTPGTDAERGPGPTPSARLDAILAQGRPTLSCEFFPPKSDRGEANLWQALARLQAIAPDF
VSVTYGAGGSTQARTRRIVRRIRRETSLPPVAHLTCVGATRRELTALLDGYRADGIDNIL
ALRGDPPEGMARFEAVAGGFAHASDLVSFITARGDFSVAVATYPEGHPESPGGMMDDVRY
LKLKQECGAVAAITQYFFDNEAFYRFRDAAAAAGVTIPIIPGIMPIADYHRIVGFSAMCG
ASIPTWLAARMEPIAGDSEAVRAAGVELAVAQCADLLAHGAPGLHFYCLNRAEMTLEIVR
ALPGVRPRPTAQ
>A0A0Q0CNS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. tagetis|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRSLLTHYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFT
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1E4NNU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. SCN 66-43|TrEMBL
MTPISLEFFPPKNDEQRAQLERALPKLKALAPEFASVTFGAGGSTLTQTPRTVRHLREVH
ALEVAPHVSCMGGTREEIGALLANYRELGCKRIVALRGDLPSGMASPGDFRYASELVDFI
RREHDGWFHIEVACYPECHPQSDHVLADLKHFKAKVDAGADGAITQYFFNADAYFRFVDD
ARAAGIDIPIVPGIMPIANFAQLRRFSEMCGAEIPRWIGKRMLAFGDDADSVREFGADVV
AAMCRRLLDGGAPGLHIYTLNRARATTAVLQRLDGPVDA
>A0A3C1ATC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHIKDILLAAKRPTLSFEFFPPRSPDSVKELQDSLQQLAAWRPDFVSVTYGAGGSTRDRT
QALVGELSQSDVFDPIPHLTCVGHTQAEVRLLLEKYAAAGVSNVLALRGDLPGQGALEGD
FKTAADLVRFIRQFNEQGLHPDPRGFGIGVACFPEGHPATPNRMLEMDYLKAKVDAGADY
LCTQVFFDNHDFHDFRARCELAGIHVPILAGILPLTQPSSLRRMAELSAGSRYPARLLRC
FQRAGEDAEAFRQVGIHHAITQCADLLDHGVVGIHYYTLNKATPTVQVLRGLGYRPYNAS
KASESEWPGILQASLTVS
>A0A5P9IM76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. THAF5a|TrEMBL
MSTQQHPLGISFEFFPPNTDAGRDKLLGVRDALAERKPRFFSVTYGAGGSTQARTLDTVS
RVRASGITTAPHLSCIGSDKGALRELLAQYREDGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFERDLENFARKMKAGANLAITQYFFTADAYF
HFVERARALGVEAPIVPGIMPITNYAKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAF
GEEVVSRLCQRLLDGGAPGLHFYTLNQAAPCLRILDNITG
>F2UPH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salpingoeca rosetta (strain ATCC 50818 / BSB-021)|TrEMBL
MPGEKIIDLITTKQNAKEKFISFEYFPPKTDDGVKSLIDRIGRYKTQDGLFMDMTWGAGG
STSDLTLDLCIRMNNEIGVESNMHLTCTNMDKEKVDIALEGAKKAGIRNIVALRGGYPEG
HCGMIKKVEDGRELTETEKGRMVQMDDGIYVCSDEDFEKEMDYLQQKIDAGADLIITQMV
FDADVYESFVKACRARGITVPIVPGIMCIQNQGGFGRMTKFCRSRVPASLRKQMEDAGDD
KEAVRQVAIKFGADLSRKLLEMGAPGLHYYTLNLEKVTLGILSELGLKK
>A0A8D3X1N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia megaterium (strain WSH-002)|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINVAGVKLAKQAAKDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLNEGVDGLLFETYYDFEELKTVLTLARKETDKPIITHVSLHDIGVLQDGR
PLADALKELEDLGADVVGLNCRLGPYHMIQSLEEVPLPDRAFLSAYPNASLPAYVEGKLE
YETNEDYFVESARLFREQGVRLIGGCCGTTPAHVRAMSSALKDLPPITSKVVKMRPAVTV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRIRGEVEGLAIAKNLIDTAYELFDGIYLITPFMRYEMTEILTRYI
HDKQLVTSERKI
>A0A847G0H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolinea sp|TrEMBL
MPGFTPGRRWQPAYYAFHNDSIPKKILATFERWVKGPLFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGSTGEHCYVDPTRPCIWYKIYERAEKLGRTDELLEVLPPLDWEKVGTEQW
WDLFEIWKKKGGLKPTIEAVKSKDRMVIFEHFMEEYRQPDWWQGDDQPHPAPAHEPVSSL
EEKLVNGQFVVTAEVAPPISATAVDLVKKVTMLKEYVDAVNFTDNPSATSRMSPLASSTL
CLQNGVEPIMQIAARDYNRMGVQSLVLGAAALGIRNVLCLTGDHARLGPEPHSRMDIWDL
DSIQMIWLLRRMRDEGKFLDQREIKTPPSLFIGAASSPNSSEQRFQVIRETKKVNAGAQY
FQTNLIYDVDSFKTYLDMLDKAGLLGRAYILAGVTPIRSVKAAYMMNNVPGVKIPTSIIE
RMEKSADPKEEGIQIGLELIEQIKDLPINGIHFMAVGWESIVPRMMEESGLQPKRMAK
>A0A7W1WW31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacterium sp. 3-1745|TrEMBL
MSEPLQQKFADPHRSVCFVGTTPPKASTEDMQMQEIADRLLARLDTLEYDGLIVYDIQDE
SSRIDTPRPFPYAETRDPREYSKLLSTNSQRPIITYKSVAQRDRADFEQWLEEAWDEYGI
RHLVLVGSPSSEGEIKLPLNTAYTALQEHSKPFHLGGVTIAERHATKGNEHQRLINKVES
GCEFFVSQAVYNAQATIDLLTSYARSCRELNVTPKRIILTFTPCGSAKTLEFMQWLGISV
PEATRYRILDAENPLAESIRICQNNLQQILDACLPLGLPIGLNIESLTNRKAEIDASIQL
YQLLKATLDLRLAERRLNQGI
>A0A8B3CFX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. TF12-12AT|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A524FZD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAKRPAYSKLCKAIEAGHFVFTGELEPKKIMDLSEIVHSAKEMKKTNRIIAANVTDGPQG
DAYMSSLIPSYVVQRDAEIEAVWQVAVRDRNRVALFGDVIAGGFMGLKNILVLTGDHTAL
GDNKKARPVYDIDSTQFCELLSKIIDDGTDYEGNEITGGKVEMNYGCVANPNAIGEYMEP
ELLKVGRKVEQGIDFIQTQTAFDIDVAKNFINELAKYKVPILLGVFPMKSYGIAWYFDQY
IPGVSVPKDLLDALKKAEKENKQDKKAKYAALDKVNVEFFVPFIEEIKKNSKASGIHCMA
VEYERLFAPLLNKYPDYAKEFY
>A0A1F2S6U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium RIFCSPLOWO2_02_FULL_68_18|TrEMBL
MKPSPVKPFLEVIDDRVLVCDGAMGTMLYAKGVFINRCFDALNLTDPARVAEVHQEYVRA
GADVIETNTFGANRVKLRGFGLADRLREITIEGARLARHAAGDEVYVAGAIGPLGIRIEP
WGKTGTDEAEAFFREQAEALVAGGVDLLILETFRDVNELRAAIDAIRGVCALPIVAQMTI
EEDGNTLDGTPPEQFAPALAPFADVVGVNCSIGPAPMLETIERMAAVTRARFSAQPNAGR
PRDIEGRNIYLSSPEYMASYARRFMSQGVRLVGGCCGTTPEHIRQIKIAVKKYAPEAARA
ATRARADVPAPPAVRVSDLAVPAVPRAERSQLARTLAEGRFATIVQLTPPKGFASDAVIE
RARALKRHGVDVVLVPDGQRGARMSALSLAVLVQQKASVETVLQYSCRDRNLLGMQSDLL
GAHAMGVRNLIIVTGDVRSVGDYPDATAVFDVDSIGLTNVVARLNHGVDIGGQPIGGPTA
FHVGVQVNPGAEDLDQEIHRFEYKVEAGAEFVVTKPVFDVATFERLHRRISAAGVPIIVG
LWPFESVLNAEFMANEVPGVRVPEAVLERMRRLETPEAAAAEGVAIAREVGRALKGAVQG
VHVAAPSGRVEAAIDVLDGLQ
>A0A7L2DA65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catharus fuscescens|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITRHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6N7YTW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis pithecellobii|TrEMBL
MDARFAPRASRFEILPFGGATAAALELAEPVTITVTCSPRHGIDRTVEIAARLAAHGHDA
VVHLAARQVLGPGHLDELAEQMGEAGIRDVFVIGGDVTEPAGPYDSALPVLEMLNDHRRR
PARLGIGAYPEGHPLISPPTLRHALAEKAKLADYAVTQICFDPNHLLAWISELRTSGISV
PLFAGVPGAVDRKRLLEISMRVGVGPSISFLRKQKGLRRLLSSPLQAAHRLHRAIAPWLG
DPALGLAGLHWYTFNRLAQTIRLEKSELGAVFDDEASEGQ
>A0A553ZZM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. P16(2019)|TrEMBL
MGLLERLKTDILVGDGAMGTLLYERGIEHQCFEEINITQPDQVISIHREYLQAGADVIQT
NTYAANHLKLSKYGLEERTAEINRRAVALAKQAAADKAYVVGTIGGIRRFQMEESTLDEI
NEALTDQLITLIDEGVDGLLLETFYDLEEALMITKEAKKHSSLPLIVNVSLGDIGVMSGG
IQATEAFSLLTKAGADIVGLNCRMGPAHMLRSFEEIPIPEHHYLAVYPNASLPDYRDGRL
FYSSNPEYFANMTGRFIDQGVRLIGGCCGTSPSHIKAVAEVAKSRVPVQKKTLKFTVREP
IPEVDLTGSEKKLTEIVRKQSSVIVELDPPKKLSTKRFMEGAHALKEAGIDALTLADNSL
ASPRIDNLALGTMVKEQVGMRPLVHLTCRDRNLIGLQSHLMGLHALGLNDVLTITGDPTK
IGDFPGATSVYDLASYQLISMIKQLNEGISFSGKDLGERANFTIGAAFNPNVKYIDKAVK
RLEKKIESGADYFMSQPVYDHQQLEAIYEETKHMTQPIYIGIMPLISARNAEFLHNEVPG
IKLTDQIREAMSTHEGNREASKQEGLAIAKSLIDTAMDYFNGIYLITPFMHYDVTVELAG
YINAKTKIKQNQSIFE
>A0A7X4YHJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus exiguus|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTVEELAPLEPGFVSVTYGAGGSTRDRTV
DLVTHIKKHTGIEAMAHLTCVGHTRDELRDVLRRLDAAGIENVLLLRGDPPLGQATFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVGALKGRS
>A0A1I0PP22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella aff. ruminicola Tc2-24|TrEMBL
MSVTGFIHQDIDSRRFSFEVLPPLKGTGTEKLFTDIDKLREFDPAYINITTHHSEFVYKE
LANGQFERHRVRRRPGTVAIAAAIQQKYGIPVQPHVICSGATIEDIEYELLDLQFLGISD
LLLLRGDKAKEDSRFMVTPGGHAHTTDLIQQVVRFNEGFFADGTPIKNPGKPFDYGVACY
PEKHEEAPNLEMDMQYLKEKQDLGAQYAVTQLFYDNDKFFAFVEKARAMGITIPIIPGIK
PFAKLSQLTVVPKTFHCDIPEPLAKEIVKCKTDEDAKQLGIEWTTAQCRELYDHGIHNIH
FYTVSAVDSVCEVVKELNKR
>K9UKY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chamaesiphon minutus (strain ATCC 27169 / PCC 6605)|TrEMBL
MFKLTIHYPPFTIHYPISHLRYDKRCSSPGAIVNNFRQAATAGEFLITAEVAPPKGGDVA
HMVQMANCLKGRVHAVNITDGSRAVMRMSPFAASLILLQQGIEPVCQFACRDRNRIGLQG
DLLGAHALGIQNILALTGDPIKAGDCPTAKAVFDLEAVRLLKIVDNLNRGLDGNDKPLPD
GAVDLFVGAAVDPQSKSISGLQRRFEQKVAAGAQFFQSQLITDFEILDKFMNRVASGYDK
PVLAGIFLLKSAKNAEFINRNVPGVEIPQEIIDRLARSPEPLREGIQIAAEQVQLASKLC
QGVHLMAVKREDLIPQILDLAGIAPLNLKS
>A0A1T4KBD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olsenella sp. KH1P3|TrEMBL
MRIDSILRSKQSFSFEIFPPRGDLSVEQARGIANEMEKCRPDWISVTFSAGGSGNSQNTV
EIARDIQEAGKTTALAHLTCLGSSKADVDSIVDRLESHGVENILALRGDRAPGREASDFH
HASDLIAYLRQRGLCVGGACYPEGHVECESLKTDIENLKLKQDAGVDFLVTQLFFRNEDF
YRFREKCTRARIKVPIICGIMPFTSVNQIQRMAFNCGASIPAAVVKRLVRAGDSPEAQRV
AGVEYACEQLEDLARNGVDGIHVYSMNKPEIARAAHECLVAAGYLEA
>A0A2G1W1V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula bahusiensis|TrEMBL
MICSMTLASVYQSTDCAISFELFPPKTSEGVDLLCKNVERLMQFSPKYFTCTYGAGGSSR
GTTLEVLQKVKQITKLPVASHLTCVGSTVEELEGYLTEAGQTGVDYIVALRGDPPKGTTQ
FEVTDGGLKYANELVELIRGRFSDLGIAVAGYPETHQEAVDFETDLTNLKRKVDAGADIV
ITQLFYDNDDFYRFRDACQKVGIEVPIVPGILPVTNFKQAKRIASMCKAAIPQSLESAMS
ESEDTQHQFRVGVEHARQQTIDLVNNGVPGIHYYVLNKSEAAADLLDGLQL
>A0A4Q7NHK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pigmentiphaga kullae|TrEMBL
MSSSLSPDAAADAAPVYSLEFFPPRDIAAQERLVRTAKQLQGLHPHFASVTFGAGGSTRD
GTMLAVSMLQKLGYEAAPHLSCIGSTPESLRDILYAYRQAGIRRLVALRGDMPSGMGDMG
ELRYARDLVEFIRRETGDWFHIEVAAYPEMHPQAQGPEADLDRFVEKMQAGADSAITQYF
FNADAYFDFVDRATAKGVLAPIVPGIMPITNYTQLARFSDMCGAEIPRWIRLRLASYGDD
RASIRAFGHDVVTELCQTLLDGGAPGLHFYTMNQADATQAVWKELER
>A0A1D9MF57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter sp. LPB0142|TrEMBL
MTTPKISFEFFPPQTLDASFRLWETAQVLAPMKPSFVSVTYGAGGTTRKLTHEAVGTIHK
NYGLNVAAHLTCVEATRAETLEIVNSYAEVGVTEIVALRGDPPKGAARFTPHPEGFESSV
ALIEALAEDGRFTIRCGAYPEPHPEAADPLADVRWLKRKCEAGATSAITQFFFEAETFFR
FRDACEKEGITAKIIPGILPIQSWKGAKAFAQRCGTSIPAWVEEAFEAATRDGREELLAT
ALCSELCDNLIQGGVEDLHFYTLNRPQMTRDVCHALGVAPEVKLSNVA
>A0A3D5H8U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MPMLRERLEQTSSFLFGVELVSIRGSMAERSAVKARTFANQLVESPHIDWISITDNAGGN
PRLAPQALAKPILYAGKEVVIHLTCKDLNRNGLESEAWQLSSEGFHNVLAMTGDYPASGN
GGTAKPVFDIDSVGLISMLTKMNQGFDGGYEKTDFLIGAVTSNCKVLEGEVVPQYLKLEK
KIECGAKFIINQIGYDSRKAHELRLYMDHHGMKHVPLIGNVYVLSPHVAQLFHDGRIPGI
VVTRPLLDLCLKQRSSPDGGKGFFQEFAAKHIAIYRGLGYRGAYLGGMSSSSSIERIMEI
ERTFSADDWKQFAREMKFSRPGEFCFYAEDPVSGLADRIKETPHPEGISKHVGTAYHLSK
WVHDIMFTPDHALSTWGEKICRQSENPNQGPALLRSLERLSKSILFQCKDCGDCSLPEIS
FLCPESQCAKNQRNGPCGGTREGRCEVDGFGDCIWLRAYERLKYEGEESNLLRHAPVIQN
QGL
>A0A7D8AZK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lincolnensis|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNILAVR
GDPPGDPMADWVAHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDSDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCETPVIPEVMPVTSVRMLERLPQLSNAAI
PSALKERILTVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTASLEIYENLG
LHHPPQA
>A0A7W1B117|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYDRVAPF
EGWVDAINAVDASGANCHMSSVGICALLTRMGYAPVLQVACRDRNRIAIQGDVLGAAAMG
VANILCLTGDGVQAGDQPGALPVFDLDCMSLLETVRTMRDERRFLSGRKLTSPPRVFMGA
AANPFAPPYEFRPLRLAKKIEAGAQFVQTQYCFDL
>A0A497DQ81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MMVLFEEYVKENLVLLDGAMGSLIYEKGVFIDKCYDELNLSRPELIGSIHEEYVRAGSMV
IETNTYGANRFKLKSHNLLDQIEEINLKGVALARQSAGDEVYVAGSMGPSGQEIEPWGDT
TLEEVFEGYAEQARILNQAVVDLFILETFQDIREMEQAIKAIKSVSGLPVVAMMTVGEDG
LTRYGVDLEDVTNALTKSEASVIGLNCTVGPKPMLDFVEQMGRLTDKPLCLMPNAGRPQF
TDGRMIYMSTPEYFSVYTKRFIERGVRVLGGCCGTTPEHIGKMANALAMKQTRIQHSINI
GVKPVSEEPLPEPVPVAEKSKLSAKMLSGQQVVLVEMVPPRSTDITKPLEGARLLQEHRV
DAINIPDGPRATARMTGLALAVLLQNQVDIETVLHYTCRDRNLLGMQSDLLGATAMGIRN
ILAITGDPPMIGDYPQATAVFDIDSIGLVHLINNLNHGIDVGEKRIGDPTSFFAGVGVDP
NSVNPENELHRLQLKKEAGAEYIITQPVFDVDSLEKFLEKADLGSLSLIAGIWPLVSLRN
AEFMKNEVPGVYVPDEVISRIAKYETKDDQLKAGIEIAQGMIDRVAGFVQGIQVSAPFGR
YKLAVEVAGAMLKRNK
>A0A7V0TLP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MGELLVDILKSPERTRVSFELLPPLKGDTIESLYKNLDPLMEFDPPYINVTYHREEVVYR
NVSDHLMERKTIWKRPGTVAISAAIKYKYRVMVIPHMICGGFTREETENALIDLNFLGIH
NILALRGDPEISTRVFIPEPGGHAHAVDLVRQIMNMNRGVYLDEELKNATPTRFSVGVAG
YPEKHPEAPNRQSDMQYLKEKIDAGAEFIITQMFFDNRKYFRFVDECREAGIQVPIIPGL
KPVATKKHLSYLPRAFGVDLPGDLVKAVEKCRSNEQVKQVGVEWAVQQCRELKEHGVPVI
HFFTMGRSDNIRKIVQAVF
>A0A7V5RIG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MNKQNFLEALRENIIIGDGAMGTMIYSKGIPTSHCFDELNISRPALIQEISRDYVAAGAQ
ALETNTFTANRHKLARFELEHLVEEINVRGVELARAAAGDQAWVLASVGPVRTGETDEVS
ARRQEKIFAEQILALVSAAPDALILETFAYAHDLELALKVALKNTDLPIIAQLSVDESGY
TRDGQHILPVFKRLRKRGAHVVGVNCARGPAGILQALEQVPLEDGLLLSAFPNAGLPAYI
DGRYHYLSTPEYFADSALRLRDQGVRLIGGCCGTTPKHIRAMANALKGLKPVTQKRSVRK
SVLVTERIPAEPKARPNLVWLVKERPTFIVELDPPRDLQHDRILHGAEALKRAGADAITM
ADSSLGVTRMSNLALGHLVQKKTGVMMVTHISCRDRNLIGTQAELMGLHALGIDHVLAIT
GDPAKFGDQPGATSVYDLNSFNLVRMIKQMNKGVAFSGRAMGQATDFTVGVAFNPNVARI
HTQVRRLEKKVANGADFVMTQPIYDPKQVKELANIARDFDQPFFIGVMPIVSARNADFLH
HEVPGILIPEWIRKRIANLEGDAARAEGVKIALQIQEEILAWFNGVYLITPFVRYEMTAQ
LVEAGKAVPQPAPASPAAQ
>A0A7W2BVL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSPPIRASRELSRPPVGVSFEFFPPKTEEMERTLWASIERLAPLGPSFVSVTYGAGGSTR
ERTHATVERIARDTALAPAAHLTCVAASRAEIDEVVRDYAKAGIRHIVALRGDPVTGVGT
AYTPHPEGYAHACDLVAGIRAIGDFEVSVSAYPEKHPESPSLDADIDYLKRKVDAGATRA
ITQFFFENDVYFRYLDKVRAAGIDIPILPGILPVTNFKQASNFASRTGASVPAWLLKRFE
GLDDDPETRKLIAAAVAAEQVTDLVDRGVGDIHFYTLNRADLVYAVCHLLGLRPEAASPA
QRLAV
>A0A8F9ZQ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. DSM 110487|TrEMBL
MSTETNDRATNDRAEPNQTTSAPVSRREALVRALRNTSYEVLPFKKTEAAVLEHVPLDVA
LTVTTTEVKGLGPTIDLAVRLSRHGYTAAPHLAARLVRDDAHLTDIVAQLREAGVRSVFV
IGGDAAEPAGTFPDALSLLRRLDEIGHPFTTVGIGGYPEGHGHIPDDLIDKAIEQKAPHA
TQVITQLCFHADTTMNWARGIQARGVALPVRVGIPGAVSRQKLVRITAGLGLGQSARFLK
KQQSMLWRFFLPGGYSPNRLVKRLTPGVGQPGSNLAGFHVFTFNELEKTQTWRKEWLARL
EAA
>A0A7W0XJS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MIEARQRAAAANRVPAISFEFFPPKSEAQAILLDDAVVRLKRFRPRYVSVTYGAGGTSQE
RSFGTVRRMTEVGLDTAAHLTCAGASSDELGETIKHFRAAGVERFVALRGDPPGGLSEPY
VPHPAGFRDTADLVKALKRAGAVEVSVSAYPERHPHSADWDCEIAALKRKVDAGADRAIT
QFFFDNDLFEAYLERVRRAGVSIPVVPGIMPIHRFNAICVFAGRCGTSIPPRLARRFDGL
DPDCETHGLVAAALAAEQVTDLMKRGVDAFHIYTLNRSELSEAVCRFCGLTPDVERAAA
>A0A0G4PSV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium camemberti FM 013|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKALGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRQTHGDYFCVGVAAYPEGHPADTFQDVQDPIRDIPY
LVEKTQAGADFIMTQLTYDIEAYQKFEHALRNHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIARRMEELKHDDDAVKRAGVDIVSEIVGGIRDIPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPSYSDAGELAIEDDPASIPLDFPGRALRRRRASSINSQPHNRVIVDKL
SVHESSQDSVHEALADSAGVPAPPPNRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTANSARRLWGNPVDSKDMSTLFRRHVSGELHMVPWSEGGAEEDGDG
LNAETELIRPELLKLIDGRGWWTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFC
SSNDYNNILKPMFAKHGHDKLTWFATNIKGDFESSLPTQPADVELDDLGSNPESVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPSETYLDTTKNDSWLVCVV
GQQFGAGTKQGSKEEEDEVKWMWRVLAGEEA
>A0A7C3PRC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTDHIKQAKSTLFSIEILPPLKGKNVQSIFDGIDPLMEFKPSFVDVTYHREEYVYKKR
EGGYLEKVSTRKRPGTVGICAAIMNRYKIDAVPHIICGGFSREETENALIDLQFLGIDNV
LALRGDSIKSEPHFVPEPNGHQYAVDLVKQIVNMNNGKYLENELEEVAPTNFCIGVAGYP
EKHFEAPNMISDLRHLKSKVDAGGDYIVTQMFFDNKRFFEFVDKCRQSGITCPIIPGLKI
LTSKKQATLLPKIFKIDVPQELLELVERCKNDNEAREAGIEWAIHQSKELMKFGVPCLHF
YTMGASEATRRVASKIF
>A0A7K0D6F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia macrotermitis|TrEMBL
MEFNPPRDSAAEARLWRAAREFERMHPAFVSMTYGAGGSTRDRTARVTGELAQETTLLTV
AHLTAVAHSVAELRSIVGVYADAGIRNLLVLRGDPPGDPLGEWEQHPEGVEYAEELVRMV
RDLGDFHVGVASFPQGHHRSPDLDHDTRFLCAKLRAGAEYSITQMFFDVDHYLRLRDRVS
ACDPVQGEKPIIPELMPITSLRTVQRAEELSGRPLPAGLLTRLERAAGNDPEANRDAVRE
VGIEIATEIGQRLIAEGAPCLHFITLNFAKATTEVLTNLGYTVAPTPVEA
>W4KK72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heterobasidion irregulare (strain TC 32-1)|TrEMBL
MKLVEKLKASDGPFYTFEFFPPRTDQGFNNLLLRISRLAELKPLAINITWGAGGSTRDRT
LELASLTQREYGIDTVMHLTCTNMEKGTVDDALRAAKELGIQNVMALRGDPPRGEEYWIP
TDPRFKHAVDLVSYIRSSPEFSDTFSIGVAGYPDGHTDNEGTEDDEIEHLKAKVDAGADY
IVTQLFYDVDNFIRWIAKVRQRGITVPIIPGIMPLQTYSSFFRLTKLCGIHVPDSMQADL
EPIKHDDQKVKDYGVSFAVNTIHRLMGRGGIRGFHLCTLNLEKNIQRTLETLGWAPGSSK
SHNRLIAETPVVHSSTADSEFMVSPASATNIAANGLSSHHRPGEGDIGKGEVNNAATWDE
FPNGRFGDVNSPAFGTQDLWGNFSRLPVEVSKQWARPQGAADITAICLRFLSSETASWPF
SPTPLSLESQHILPHLKRLARAGWWPVGSQPAVDGQRSDDPVFGWGPANGYVFQKAFVEF
FVGIDAVERLEKRVKAQGKGSVDLLAASHTGELRTNIAEGERNAVTWGVFTGQEIVQSTI
IERESFMTWKDEAFSIWNDWASLFEPGSEERALLEDIRNTRWLVNVTHHDFKDPDALWRF
LFEDAPEASAGR
>A0A2P6HHM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium SEEP-SAG10|TrEMBL
MGQPRLGALESMDLRGLSVNSEKVVMNLNTFHTKRELDGLLEKAAKSNLKYILVVRGDGG
PLMPKLDAKSIGGARSVATSIDLIRYINGQYAGQFITGAAFNPNNPMPFELNRMEQKIEA
GATYSVTQPIIGKDEHVDKLKDFDIAVVVEAWMSVNIDLLYK
>Z9JTR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium phenoliresistens|TrEMBL
MSIAPQVPHDAAAGAGAAPAASRAEAPAPRSRRPALSYELFPARGDASLEKVRRTVAALE
CTQPDYVSVTCASARTNFPRVLELTDHILSETGLRPLVHLTSVGSSAADLSVSIRTLMQL
GVRGILALRGDIPPGYDTRDDEFPFARYLVELIRRIEREETATLAAGRLAVGVATYAQRH
PESPTHQHDIEVLLTKERSGADFAITQAFFDPAEYSDLVRRARRAGVTIPIIPGFVPMTS
VRRLTRFAELSGVHAPAEHLHALETASGPEERRRIGIAASVDLIRAVLDDGAPGVHLFTF
NEHVDALGVLDRLDLGRWAREPVGV
>A0A2N7RH82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. AD80|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRAKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRDSIRAVLADFKAAGVNRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGANAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAATTALWQRLVK
>A0A2A4P8Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MTTGQSRSKRFAGDTGINVSFEFFPPKSEKMEKTLWDAVRRLEPLSPNFVSVTYGAGGST
RERTHNTVSRILSETTLCPAAHLTCVDATKEEIDTVIQGYHDIGVRHIVALRGDSAEGVG
GKFQAHNSGYVSSYDLVAGIREIGDFEVSVSAYPEKHPXSPDFASDIDMLKRKIDAGATR
AITQFFFDNEHYERYLERVRAAGISIPIVPGIAPVHDFRKLSNFASXTGASVPDWLARRF
DGLENEAETHRLVAAAVTAEQVLDLVELGIQDFHFYTMNRADLVYAICHLLGLRPHTHQA
A
>A0A661XQS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHIKNADKTLFSLEILPPKKGDNINDLFNHLDPLMEFNPPFVDVTYHREEYVYKKM
PNGLLQRKTTKKRPGTVGICAAISNKYNVDTVPHIICGGFSKEETENALIDLNFLGIDNV
LLIRGDAIKSELRFVPDPEGNNYALDLLNQVKGMNNGLYLDEELQNASSTDFCTGVAGYP
EKHFEAPNMKSDIKFLKQKVAAGADYIVTQMFYDNQKYFDFVERCRAEGIDIPIIPGLKP
IT
>A0A420TF76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella intermedia|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIHDIALLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A2N0L0W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G2|TrEMBL
MKITEKSYQASGRSCFICDFSPARSGDPGQVDQADIEAEMLAVAYNPGRAVRANSAMLAA
AIKSRLGKEASFTLATRDMNKLAAESQLLGAQLLGLENVIVVSGDPFSERDMGRTKEVGD
QLPTQLIAAIASLNRGLDFRESQLRAATDFCIGATVDLGRMLEPEAALAHRKVQAGAHFL
ITQPIFDPGQAASFEQAYEAVSGETLNLPIFYGLQVLEQDGVLFSTVPDAVREELAQGTP
GVQIALELYRRFLDAGLHDIYLVPPIRRGGARGYNAAREFLSGAGGR
>A0A4Q3G8W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MVHNTNNTNRLGELLANARLEILPLAGIRDQVTDVIPTGSTLTITCSPKHGVQRTVETAE
FFAARGYEVIPHLAASEIQNHRHLGEIVKRLSASGINEVFVIGGDGQAGGKAYSCAADLI
DDLVTLPDRPSRIGVAGYPEGHPDIPAEDLAEALRRKSRHASYVVPQMCFDPTVLREWLA
TMSVLHPDLPVVLSAPGAVARRKLLEMSPRIGVGNSVRYLSKNKRAMTKLLLHRTFTPDS
LLEDVMADETVSARVIGLHLFTFNQLTDTEQWRAHQHAAWQPSSRRPAKQVSADEKERSL
LPGE
>A0A2A4XRQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MMATDLNSQILTNFLNGYTAEVTSGDKKSMAAAEKMMDKGAEVFVASLPKDTIDKQVAAV
VKIHQAGLKPVPHIVARNIKNLAALETTLNRFVIEAEIDTALILGGDRDDAVGDFDASLQ
LIETGLLQKVGIKKIYLGCYPEGHPRISTEILDKSRAAKLIAAEKAGLEVELVSQFCFES
QPIIEFARKLRAEGVKVPFRVGVAGPSSRATLVKYAIICGVGASLRALKERQDLAKNMTS
GETPEKLITELAEALEQQPELGLNGVHFFTFGSLEKSATFVNQVVN
>A0A4U6M2A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. wls619|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYAADLVSLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDEDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A357CHI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MLAAPERKSRFLGGGDIDVSFEFFPPKTAAMEETLWRSIRRLEPLDPRYVSVTYGAGGST
RERTHATVARILRETKLKPAAHLTCVAATRGEVDEVIRDYWDLGVRHIVALRGDPPGGIG
ERYVPTPGGYINAADLVKGIRAIAPFDVSVACYPENHPESPTVDAEIDMLWAKIDAGAST
AISQFFFDNEVFFRYLDRVRARGITIPIVPGIIPIHNFKQVSGFALKSGASVPEWLGHRF
EGLDNDQETRYLVAAAVATEQVMGLVDQGITEFHFYTLNRADLVYAICHLLGLRPAAATA
KVEAAQ
>A0A3R7ADP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM07-10AC|TrEMBL
MKITDVLQSDKITLSMEVFPPKTTTAVEKVNEAVREIAALKPDFMSVTYGAAGGKNSKYT
IQIAQDIKDSYGVNSIAHLTCLSSTRETVENQIGLMRDAGIENILALRGDIPKEADFPLP
DQFHYAAELVREIKRLAPDMCIGGACYPEGHPEASSKAEDILHIKEKVDAGCEFLTTQMF
FDNSIFYNYLYRLREAGILVPIIAGIMPITRKNQVARSIQLSGSCVPARFKSIVDWFGDE
PAKMKQAGIAYATDQIIDLIANGVKHIHVYTMNDPEVAAGIQNNLSEIIG
>A0A2N5RKU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga sp. KOL6|TrEMBL
MKKSLENGKCVVLEVLTPRGTNLKKFFDFTEKAWQTGIDAFTVTDMPMGRVRMAPWAVSH
LLIESGKEVLMHFTRNTRNMIRIQSDLLGCHALGINNLLLLSGDNPVHGDYPKTTSVNDI
DILDLIRLTKLLNEGKDLAGNKMNGKTNFFVGGALNPFSNKDIERAKQKIEAGIDFLVTQ
PLFQGNVARTLKDKLNTKILASIVFFESVKQVGYFSGVPGIEIPKEIIDSSEKGDEYVKE
KSFEAVLKFVEETKNVIDGFYIVAIVKDLEKIRKVVEIAKN
>A0A5Q5CDU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. (strain JLS)|TrEMBL
MTSTDLQCPKRMQFGPCGGVRPDGQCEMRTGPCAFPDVVPWSGVEPASRPAQAPLVLTDF
SCAPFDEDDVAATARILGRSCDAVLVGEHQNRPDFPPTLMGRLLLEAGVTPWITLSCRDR
NRIVLEQELRGLRSLGVGTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGMVPAV
PETPTAPPVHARPARLVEKQRAGASLAVLNHVPYPDTIADFMATARAAGLSIPVVAAVAV
FTDVVSAAVLQGLPGLELDQSVVDEVLGAADPVSAGIAAAVAEARALLAIDGVDGVNVSG
LASASGTRVGAEIKAEVGRLVKAEVGA
>A0A4S5ATK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp|TrEMBL
MTQASSRIGDRIRSGERSFSFEFFPPRDEAGEEQLWNAIRALEPYQPTFVSVTYGAGGTT
RDRTVTITGRIARETSLVPMAHLTCVGHTRDELEGILDSYVAEGVNHVMALRGDPQEGPR
AEWTPTAGGLNYAVELVELARSRGDFVVGVAAFPEGHPSAESRDHDADVLVAKARAGAEF
AVTQMFFRAEDYFGLVDRVRERGVDIPILPGIMPILNLSAIRRQGELIGTSVPDEIVERI
TAAGPEPADVRAEGIKLAAELCDDLLRGGAPGLHFYTLNRSKATLEIFEALQITV
>A0A3B9AG07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
GGATELVHANELVAFIRKHFGEEFTIHVAAYPEIHPEAESYQADIHWLAEKFQAGANAAI
TQYFYNIDAYWYFIDQCRKAGIEQAIVPGIMPITNFQNLARFSANCGAEIPRWISQRLQQ
YGDDQHAVRDFGIEVVTRLCEQLLEGGAPGLHFYT
>A0A6B0WD41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
GADAINIGDSPMARVRMSALALALRIEREVGIETIIHQTTRDRNLMALQSDLLGAHSLGI
RNVIALTGDPLPEASESSAVWDVDSIGFVRILKRLNEGVDFAGNSLGRPTDFFVACAANP
TADDIDIELRRVRAKLDEGGDMLMTQPVYDLATLSEFFERLGPVDVPVLLGILPLMSSRH
TEFIHNELAGVVVPDAVRARMREAGDAGAAAGLEIAYEQIEETRDFEWVSGIYIMPSFGR
YEVAAELIERVRATAPVTTR
>A0A535RKF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MEHTLLTQLQQRPLLCDGAMGSLLYARGITYEKCFDALNLSQPELISSIHREYINAGAQI
IETNSFGANRAKLEAYNLEGQVRDINRSAVRLAREAREVSGQPVFVAGAVGPTGRPLQAP
DEHRLSELRAIFREQIEALLEGGADLLILETFSSLAELRQAVLAAQEVGGLPVVAQMSFY
EDGHTLSGQSAARVAAVLSDLGVDVMGANCSVGPAATFDALQEMITQINQQQNDRTPLFS
AQPNAGLPTRIDNRFFYVATPDYFADYALRFVKAGVHLIGGCCGTTPRHIAAMRSALDGL
YGTSLQSSNGAAEKTVPSVSTAASSGQEIIARLIEEEIILPQQGSKTRLQEKLAAGEFVV
SVELDPPKGLNPGKILEGAALLQEAGVDCINIADSPMARVRMGCIALARLIQDHLGIETI
IHFTTRDRNLMALQSELLGAHALGIRNILALTGDPLRVGDYPNTTGVWNVDSVGLMAVIK
GMNEGHDAAGSSIGAQGSFHIGAALNLNMTEEQTEQEIARYWRKIEAGAQFIMTQPIYEL
APLLRFLECVGTPPIPLILGCIPLHSSRHAEYLHNEVPGITIPDDVRARMRLAGEHGHEE
GLKLAQELLIAARSQIQGVYLMPSYGRYDVVSKLTTMLRARQNATI
>A0A7C1KCN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTAPCPAARPQQRIADLFRAGEPLFSFEFFPPRTDAAARALARTVAELAPLNPAFVSVTY
GAGGSTRALTLETVSRLRAETGITVMAHLTCVGHGRAELHRILADLRRAGVRNLMALRGD
PPRGEAAFVPPADGFAHADELIRFVRAEGFDFCIGAACYPEGHLESEDRAQDLVHLAGKV
AAGAEFLITQLFFDNAFYFDFLRRARAVGITVPILPGIMPITDVAQVQRITRLCGATLPT
RLQLQLERCGTPEEVFQVGLRWAIMQCRELLAEGAPGIHFYTLNRSPATRLILGAIRSA
>A0A6L7Y5R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
AAPRAPTHPPGGGGPRPGPAHPRGAGAAPRGGGAARGAAGADVVGVNCGVGPRAALDVLE
QIAAADPAARLFVMPNAGLPRITGGRPFYPSSPEYFADFALRAKDLGAAIIGGCCGTTPA
HTRAMRAALDSAERMPATVEVLSRGPVLAVSDTRGGVDITATPPAEEPPEPDEPSRLRDK
LAAGQYVVSVEIDPPRGHNPRKAVEGAGMLRDAGADAINIGDSPMARVRMSALALALRIE
REVGIETIIHQTTRDRNLMALQSDLLGAHSLGIRNLIALTGDPLPEASQSSAVWDVDAIG
FVRILKRRNEGVDFAGNSLGRPTDFFVACAANPTADDIDIELRRVRAKLDEGADMLMTQP
VYDLATLTGFFERLGPVDVPVLLGILPLMSSRHTEFIHNELAGVVIPDDVRARMREAGDA
GAAAGLEIAFEQIEETRDFEWVSGIYIMPSFGRYEVAAELIERVRATAPVRAG
>A0A536M9H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAADKKRSNPFLERLRRGPLLGDGAMGTQLHARGVSFQRSFDELNLTEPEIVEEIHRAYI
SAGAELIETNTFGANRIKLARHGLDGRVRDINVRAVKLAREAREIAGEPVFLAGSVGPIG
QQLEPIGRISIAQATAAFEEQIAALLEGGADLLVLETFTNLPELLAAVAAARRTADLPIV
AQMTFAEDGLTLSAEEPSQVVQALERAGVDVIGVNCGVGPQVALQVLEAMRQQTRLPLSG
QPNAGLPARVEGRFFYFATPEYFATFARQAADLGVAYIGGCCGTTPAHIAAMRAALKPVP
ATTRIQRPSPSTAIPIDLNPAEQLPPTPFAQRLAAKAFVVSVEIDPPRGLNPAKCIAGAE
LIKAAGADAINIGDSPMARVRMSALSLALMIRQQVGIDTLIHFTSRDKNLMALQAELIGA
HALGIRNIIALTGDPPRIGDYPSATGVWDVDSIGLIKILQRLNEGYDWLGTSIGKPANFT
IACAVNPSADDLDHEIDRFRQKIEAGAHVAMSQPLYDHQTLERFFEKTGPLPIPFLLGVL
PLQSSRHAEFMHNEVPGIVVPDQLRERMRRAGENGIAEGLAQSRELLQDTKDLVQGVYLM
PSFGRYEVVAELVRWLRQASISRVR
>A0A535FPZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQHDFLEQLQQRPLLCDGAMGTLLYARGIAYERCFDELNLTRPALIQGIHSEYISAGAQI
IETNTFGANRAKLEAYNLEGRVRDINRHAVKLAREAREISGQSVFIAGAVGPSGRPLQAP
DEQRLSELRAIFREQIDALLVGGADLLILETFSSLAELRQAVLAAQDVGGLPIVAQMSFY
EDGHTLSGQSPARVAAVLNDLGIDVMGANCSVGPAATLDVLQEMIAAARLFLDNEQAIPQ
MFSAQPNAGLPTRIGNRFFYMATPDYFADYAVRFARAGVQLIGGCCGTTPHHTAAMRKAL
DDAYGATTPSIPGSSRETLHTKPVEITNGKVTIAGLIEEEVILPQQGTKTRLQEKLAARE
FVVSVELDPPKGLNPAKILEGAAMLQKVGVDCINIADSPMARVRMGCIALARLIQDHLGI
ETIIHFTTRDRNLMALQSELLGAHALGIRNILSLTGDPLHVGDYPNTTGVWDLDSVGLIQ
VLRRMNEGHDAASSSIGAQASFHIGMALNLNMTEQETEQEIDKYRRKIEAGAHFIMTQPI
YELARLERFLARAGKPPIPMLLGCIPLHSSRHAEFLHNEVPGITIPDDVRSRMRAAGDQG
HEEGLKLSQELLTSARSMIQGVYLMPSYGRYDVVSKLTKMLQMQPTP
>A0A7K2IFI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID6137|TrEMBL
MTTFSFEFFPPKTPAGERTLWQTIRRVESLRPDFVSVTYGAGGSSRDRTIEVTRRIAAET
TLRSVAHLTAVGHSVAELRHIIGSYAAAGIRDVLALRGDPPGDPRGPWVPHPDGFTHAVQ
LVELVRSLGDFRIGVAAFPERHPRSPDWDSEIRHFVAKCKAGADYAITQMFFHADDYLRL
RDRAAAAGCDIPIIPEIMPATDVRQIRRFAELSGAAFPEDLAHRLEAARDDPAAAHRIGV
DHATAMADRLLTEGAPGLHYITLNRSTAALDIHRALHVSRSTSVR
>A0A8J7V9R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Obscuribacter sp|TrEMBL
MSHPFLQALAKRPLLADGGIGTLLYSRGASTDASFEYLNVSKQDTVQQMHVDYINAGAEI
IETNSFSGNRFKLANHGLDGDVWKINVWAAKIARNAREITGQPVFVAGSIGPTGKLLPPL
GDTQKDELTAVYQEQMEALLAGGVDLFMIETMSSLEETAIAIRAARKVSQLPLIAQISFS
VEGHTLLGATPEDAIKLLNDLGDDMPDVIGINCGAGPGPVFDSFLRLTTAVRSMGIPESR
LTFSCLPNAGQPSLMGGRPIFMSKPKYCASYIEPYLNAGARIVGGCCGTTPEHIKAMRES
LDRYIKDEVAGTNKPHAQVLFQTESLAETIEPPTEKSKDDKVRLADRLRAIKANGNDTDF
YISVELDPPKGAGIKKISAAAELLHNAGADAINVGDSPMARVRMSSLATCQLLSQKLDVE
TIIHFTTRDRNLMGIQADLLGCQALGLKNILALTGDPPALGNYAHATAVYDVDSIGLIKI
IKQLNSGQDIAGNTIGTPLTLSIGCALNPTTQNRALELDRIRRKIEAGADFIMTQPIYRK
SDLTDFLDEMEGSPVPLLVGIMPLHSSKHAEYLHNEVPGISIPKHIREAMAKAGEEGAKV
GLQLAEELLEELRPIIQGTYLVPSFGRYEDMAALVTRLKSKVKTIVKK
>A0A6B1DZK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSQLTFRKRLWTGAPVLADGAMGTLLHEHSHARADACFDAMNLDAPGVVRGIHLAYLEAG
AELIATNTFGANSFKLASAGKADKLAQINQLGVQLAREASAQSGCAAFIAGSVGPLGVGI
APFGAVSQADAREAFALQLRALLGAGVDLIQFETFREHKELLLAVTALRDLSPDMPILAQ
ATFYHENLSYAGYPPARVANDLGRAGVDVIGVNCGSGPAGITAVLRQMRFALPDAKFSVM
PNAGFPEVVGGRILYPASADYFADFATSAVEMGAAIVGGCCGTKPEHIAAMRAALDAPPR
KRIDLHITESALEQETQAPDAPTELAERLAAGIFTATVEMAPPRSYRTEALLNAARRLRA
AGADLINVADTPAARMKMSAWAVAHLLQTQIGMETVLHFPTRGRNMLRVQGDLLASHALG
LRNLFVVLGDPTRIGDFPDASDLNDVAPSRLIQVIKQGMNRGVDMAGNSIGKPSSFTVGC
ALNMGAEDTDREIRILRKKLAAGVDFALGQAVFELERIVHFRHRYQELCGEDFALPVLMA
VMPLRSLRQARYLHNEVPGIQIPADIMARLAAAGDEAPRAGLQIARELLDAMASLVQGAY
IIPAGDYELAAELVASIKERGGLQ
>A0A535W417|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRDKGAPSRPFRSGRVFPCQVPVPPPPQPEPNLANSLPQDRFRARLTERPLLADGGMGTL
MFSRGVPQGACLDELAASRPDLVSAAHREYLEAGAELIETLSLGANRRRLALYGLEHDVG
RLNRRAAQVAREAREVSGREAFVGGSIGPIAPPSRSATRPREQSARAIFREHIDGLLEGG
ADVLILETFSDLDQLLLAIDEARQAADVPVIASLTFGEDLALADGTSPERAWAALVAAGV
DVVGVNCGAGPSASIDAIERMGPSTGGAPFRSIMPNAGLPQRLEGRFVYSAGADYFAGVT
PRMLAVGARIVGGCCGTTPAHVAAMRIALATPAAATSDLEAPGATGEKRKTSPSALVMER
TSTDGQERPAPTHLAELLTTRRFVVSVEIDPPRSVRIERTITAARLLREAGVDVVNISDS
PMARVRMGAFAVAFGIQHDLDLECLVHCTTRDRNLMALESELLGAHALGVRNIIALTGDP
PRVGDYPNGTGVWDVDSIGLIDILSRLNRGEDQSGSPIGQAAGFTIACALDPTAADAGSE
WDRLERKLAAGAHLVMTQPLYSVRQVEAMLDEARRRFGQGGFPVPVLLGVLPLVSVRHAE
FLHNEVPGITIPDEARAAMHAAGERGSELGIEMADELLATVEGELAGTYIMPSFGRYEQC
AGLVRRIRERHPQGSPVAVGAGPALGAAQ
>A0A535UCB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQHDFLEQLRQHPLLCDGAMGTLLYARGIAYERCFDELNLTRPALIQGIHSEYISAGAQI
IETNTFGANRAKLEAYNLEGRVRDINRHAVKLAREAREISGQSVFIAGAVGPSGRPLQAP
DEQRLSELRAIFREQIDALLVGGADLLILETFSSLAELRQAVLAAQDVGGLPIVAQMSFY
EDGHTLSGQSPARVAAVLNDLGIDVMGANCSVGPAATLDVLQEMIAAARLFLDNEQAIPQ
MFSAQPNAGLPTRIGNRFFYMATPDYFADYAVRFARAGVQLIGGCCGTTPHHIAAMRKAL
NDAYGAATPSIPGSSRETLQAKPVEITNGKVTIAGLIEEEVILPQQGTKTRLQEKLAARE
FVVSVELDPPKGLNPAKILEGAAMLQKVGVDFINIADSPMARVRMGCIALARLIQDHLGI
ETIIHFTTRDRNLMALQSELLGAHALGIRNILSLTGDPLHVGDYPNTTGVWDLDSVGLIQ
VLRRMNEGHDAAGSSIGAQASFHIGMALNLNMTEQETEQEIDKYRRKIEAGAHFIMTQPI
YELARLECFLARVGKPPIPMLLGCIPLHSSRHAEFLHNEVPGITIPDDVRSRMRAAGDQG
HEEGLKLAQELLTSARSMIQGVYLMPSYGRYDVVSKLTKMLQMQPTP
>A0A7X8E0P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonadales bacterium|TrEMBL
MGFHSARHVDALNQTMSELKGDINVSFEFFPPNSEKMEQTLWDSIERLTTLEPKFVSVTY
GANSGTRDRTHKVIKDIQDKTGLIAAPHLTCIDASRDELRAIARDYWNNGIRKIVALRGD
LPEGLAKPDMYAADLVSLLKEEADFDIAVAAYPEVHPEAKSAQADLLSLKHKIDAGADSA
ITQFFFDVESYLRFRDRCATVGIEAEIIPGILPVSNYKTLLKFAGFSNVRIPNWMHQRFQ
GLDDDQNTRNLVGASIAMDQVRVLSQEGVKDFHFYTLNRSDLTYAICHSLGVRPSAIAVP
D
>A0A536BBD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSPAPERNKPRLHPFLERLRRGPLLGDGAMGTQLHARGISFERSFDELNLTEPKIVEEIH
RAYISAGAELIETNTFGANRIKLARHGLEGRVRDINFRAVKLAREAREISGEPVFLAGSV
GPIGQQLEPIGRITIAQATAAFEEQIAALLEGGADLLVLETFTNLAELLAAVSAAKKTAD
LPIVAQMTFAEDGLTLSAEEPGQVVQALERAGVDVIGVNCGVGPQVALEVLEAMRHETRL
PLSGQPNAGLPARVEGRFFYFATPEYFATYARQAAELGVAYIGGCCGTTPAHIAAMRAAL
RPVAGTPRIRQAPASTAIAIDLNPAEQLPATPFAERLAGRSFVVSVEIDPPRGLNPSKCI
AGAQLIKDAGADAINIGDSPMARVRMSALSLAIMIRQQVGIDTLIHFTSRDKNLMALQAE
LIGAHALGIRNIIALTGDPPRIGDYPSATGVWDVDSIGLIKILKRLNEGYDWLGTSIGKP
ANFTIACAVNPSAEDLDHEIDRFRQKIEAGADVAMSQPLYELETLERFFDKTGPLPIPFL
LGVLPLQSSRHAEFMHNEVPGIVVPQPLRDRMRGAGENGIA
>A0A2E5L0G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MEPSEKLQNSLRGMLKNSDRFLTAVEIETSRGLLMSEASRKTSELAKSLSEFDRVDFVAL
TDNPGGNPHIRPEVLGQDLLFRGRDVVINMSCKDYNRNGIESRLWALGSQGFTNVLALSG
DYPIGGFQGQAQPVFDIDSVGLLELMSQMNDGLPNQMWGSAGREDRLEKTDFFAGCAVSP
FKKFEGELMTQYFKLAMKVRSGAKFAVTQIGYDSRKASELHQYVNSNNIDIPLIGSIFIL
TAPAGRFFNRWGVPGVWVSDELRDIANKQAKSKDRGRAFFSELAAKQIAILRGIGYRGAY
ISGRPQLKRIQSILEMADSFGENDWKEFAKEINFSQKDEFYYYEQGDNAGLSSDVVNKSY
LSSKTKSARSKAKFSVPIQFRLGKFVHDRVFDKHSTGFKVGRSVYRQIDKSKKLSGVAHV
LEQVAKVPAYNCRDCGDCSLPDIAYLCPESQCVKSQRNGPCGGTKAGKCEILDQKCIWIR
AYDRLKPFGDEEKMLQRPVVFRDGSLKNTSAWGNTFLSRDHHGRQNPNTVDGEA
>A0A523BXI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLAKAGSNSYWAEVEMDTKSKFLEKIQADRPLISDGAMGTLLHQRGVSFDQSFDELNLTS
PALVADIHREYIDAGSNIIQTNTFSANRYKLAQHGLEKRVREININAVELARRVVLASYK
DVLIAGDVGPLGVRLAPFGRVQPEEARIVFREQIDALISANVDLLIIETMTDLYELREAI
LAARDINSDIPVVASMTFTRDDRTLLGDDPAKVARKLREAGADVIGVNCSGGPNQILRIL
KQMVQAVPQGKFSVMPNAGWPEQVAGRIMYPASPEYFADYALAFWHAGACLIGGCCGTTP
KHIAVMHQAIENAPPGSAPNGFTLTAVEREEATPEGMQPTQLAEKLANGQFVFAVEVDPP
RGLTAQKLMAGSSLLKEAGADVINVADSPMARMRMSPWAVCRLIQEKVGIETVLHFPTRG
RNLLRVQGDLLAAHALGVRNVFVVMGDPTAIGDYPDAMDNYDLVPSGLIKLIKQGFNTGV
DHAGADIGQPTSFFAGCALNLTAADPDHEIKNLHRKLRAGADFILTQPIYNPPAAKAFME
RVDEELGGLKVPVLIGLLPLVSVRHAAFLQHEVPGIEIPDEVQSRMAHSGDREARTGIEI
AIELIDQIKQFAQGIYLMPAFNRFDYAAEIIETIREGN
>A0A3C0ZYJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKLGELFQNGKFVITVEAGPPKGVDVKQMLEDVELLRDRVDAFNVTDQQSSVMKLGSLAV
SHLLKERGVEPIYQLTCRDRNRIALQSDLLSAYVLGIENVLCLTGDYVTLGDHPSAKPVF
DLHSVTLLLTLSRLQKGYDLAGQELKGKPEFYVGAVVNPGANPLESQIIKMEKKIEAGAQ
FFQTQAVYEPEKFAAFMKRVEGFGVPVMVGIIPLKSAGMARFMNRNVAGVHVPDHLIAEM
KETKDRAKTSVEIAGRLIREMKGLCQGVHIMALGWERYVPAVLDAAGL
>A0A094S1Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|actinobacterium acAcidi|TrEMBL
MARIGDLLAAGRTFSFEFSPPKTTAGSMSLGRTIAELESLGPSFVSVTYGAGGSTREHTR
DTVLWVERETNIPAMAHLTCVGHTRNEIEDIIATYTAAGVENVLALAGDPPKDPADARPS
DYEYATDLVEHLREIADLSIGVAAHPEGHPRSPDLATDRRLLAEKLKVVDFATTQFFFDI
DHYLSLVNDLADLGVTKPVVPGIMPCTNIAQVERMAELSGAAFPGWLRERLESGTSPEDV
RRIGVEAATELCAQLLSAGAPGLHFYTLNKSTATREIYAQLGLPVA
>A0A521UPU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGLREKLGEQFVLTTELGGTNGTDVAKSLEDARAYHHIDALNTIDCASARLRMNAFMVGY
LIQRELGIEVIPHLTCRDRSILGLQADLLGAHALGLRAVLATTGDPPSAGPYPSKAVYDV
NSVRLIKMIADLNRGVDYNGDQINGHTDFLIAAVAAPAAPNLDAVARNVERKKEAGAHFI
QTQPMFDVAQTRAFLEKVRPLGLPILVGVMPLRGLKMAEFMNKEVEGVSIPQPVIERLKG
GTTGVQIAQEFVEELHGEVDGFHIMSMGNVKATNEIIDHLVKLVKVGRGYRLRAELETGS
>A0A536KXI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKRVTLADLLRTPRYEVLPTDDAADRVLAYVPKDVTITVTASPRRGMPATVHLALRLAQL
GYQAVPHLSARLIRDTHELGQILDALRPAGITNVFVVAGDAREPAGMFPDSLSLLAALPP
DHGLKEIGVTGYPESHPFIHDDVTIQAMWDKRRLATYIVSNMSFDPTTVTYWLERVRRRG
VELPIHIGMAGVADPIRLLKVSTKIGVADAARFLRGHPSWVARMFRPGGYEPGRFVTAML
PAMSSPALRVAGLHVFTFNEIEPTERWRREMLLRVA
>A0A372QH58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus sp. MUCL 43196|TrEMBL
MKVINKILKAHEEGRPSWSFEYFPPKTQQGVQNLYDRMERMYRLGPEFIDVTWNAGGTTS
QLTSEIVATAQSVYGLETIMHLTCTNMPKEKIDKALKDAKECGCQNILALRGDPPRGQEH
WEACENGFSHAIDLVRYIRQQYGDYFGIAVAGYCEGHVDNPDKDDDLYRLKEKVDAGADF
IITQVFYDVDIFLNWVKKCRAIGISCPIIPGILPIQNYSGFNRIITLSKTIVPQFVLEEL
EPIKDDDAAVKEYGIRLAVDMIRKMFADGIKCYHFYTMNLERSTRLILEALEFVPPIENV
KPLPWCPSLSAKRKKENVRPIFWRNRTKSYIARTEAWDEFPNGRWGDSRSPAFGELDGYG
VSLKHSKKGALELWGYPQKHSDIFDVFVQYCRGEVNSLPWSDQPLAEESNIIREQLAHIN
SMGYLTINSQPAVNGVRSDHKIFGWGPKNGYVYQKAYLEVFISPTQLDALIARIERDTNI
TYYAVNKQGDLKTNTQSDGPNAVTWGVFPGKEIIQPTVVEAVSFTAWKDEAFELWNEWTK
IYDTDSISAKLITDIADNWYLINIVHNDFHDSDGIFKIFEQISVTDYEADR
>A0A3S7JYK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. ZAC14D1_NAIMI4_6|TrEMBL
MPAAPTHAARAFIDACSLEVSAKAMPALHAEAARIAPGTTISIPYLASEDDDARIAAARR
VRELGLQPMPHLSARRIGSLAALERFIARAVGEAGVEQCLLVAGDLATPAGPFADSASLI
DTGLLERAGIKVVAVGGHPEGHPVMGADERWQVLERKCHAIQARGMAPKIITQFAFDADI
VLAWLDALRARGIGHPVLVGVPGPASVSRFLRYAAMCGVGASASMLARYGISIGRLLGTA
GPDVFVDRLVGGLTEAHGQVSPHLFPFGGIAPSLDWVAQYRLRVGAGRR
>A0A2E9D9X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGFIQEIEETETKFGNVFITDISPPKGVNNVGYESIININSDFLLIIDSPGGSVRSAPIP
FAYKLSYQENQNVIFTLNCRDMNKLAIQSNLLGAQMLNLNNVFVVNGDKSTKQKKSAKTV
NDYTTTTLISDIVNLNHGMDFQQSKLDSIATFTVGSAIDFSKVPQINEIKLVRKKITNGT
DFFISQPCYDTSLILDFHKAYYSQYGYRIDKPIFYGVQMLSKTGRNWGFIPEDVENEMKS
NVSSLEIALKFVQELLSLGFNNIYLVPPIENGGVRDYYMAQLLIKKIRSM
>A0A2E0D305|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQKYSIEIIPKQIELLKYLPRDIFNEVYVAYIPGDRFENIVKASKSLIKNGFNVIPHCPA
RTIPSKKDLDSYLSQLSSVGVKKILTIAGSGNNHFESTENANNNFSNTIEMLETGLFEKY
QFEQINIAGHPEGNPMDPESDKNLQLKCQWLLQHNFNSSIVTQWTTNVESTNKWILDTKD
MIKSKFDNKMSIIIGIAGPAKLTTLINYAKICGVNATTLIIKNKKLGLRNLIRHNPTEII
DGLRNYDSLHFFPFGGIKEICNWFDEKVKS
>A0A2E6KG75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKKFSIEILPKQKDKISQINKDYFNDVYVTHIPGSPAADLVETSIAVLENNLNPVPHIPA
RSMESENELDDLLGNLNHANVKNLLLIGGSAKNVTGPYESTSQLINSSILEKYEFENIRI
AGHPEGNPDDKNSKESLVEKLELLNNKYKISIVTQFSLSSTITNNWINETRSLFKNKIKN
VEIIIGLAGPSKITTLLKYAKVCGVNASASFLKKQGLDITKLIKHSPEKILNELKNYDGI
HFFPFGGINELNLWAINNRKEISE
>H1HS02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stomatobaculum longum|TrEMBL
MEEKPVTLSLEVFPPKTSEKYEATAENAKKIAALHPDFMSVTYGAGGGTGDFTAEIAAEI
QNGYGVPTLAHLTCVSSSREHVTKMLSLYKEKGIENILALRGDLPQDGTRSEDYRYAVEL
IRDIKEREGDTFCLGGACYPEGHVECAHKEDDLGYLKEKVDAGLDFLTTQLFFDNNIFYN
FLYRAREKGISVPIVAGIMPITRAEQLKRSVAMSGTEVPQRFRAIVDRFGERKGAMEQAG
VIYAAEQIVDLIANGVGHIHVYTMNRPKIAKAILEQLSEILD
>A0A535WW03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
EKTLELVTRIKRHYHIEAMAHLTCANTADRTRQILNWMEREGVANVLALRGDPPVSGEPF
VPADPKLVHASDLITLVRGSGYRFGIGAACSTEKHPESPDLEHEFRYMQLKVDSGADFLI
TQLFFDNRFYFDLVARARAAGIKVPIVPGLMPVPSRRSLAVMTAMSGATVPPALQSAIDA
APDDDAIRALGVRHCIAQCAELLEAGVPGLHFYTFNRARAPIEILAALRGQQLLAS
>A0A3B8XC02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIVDLLTRGRPTVSFEFMAPRDETEVEVLEKTVATLAGHAPDWVSVTYRLRTGEKTLEL
VTRIKRHYHIEAMAHLTCANSRDETRRILNWMEREGVANVLALRG
>A0A3S3PN83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter chitinilyticus|TrEMBL
MKITEHIKNAKGKTLFSFELLPPIKGQSIDWIYNGIEPLLEFQPPFIDVTSLREDYIYKE
QPNGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADSSFVPTPGGHAYATDLIQHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNTDFKYLKQKVDMGAGFIVTQMFFDNQKYFEFVRKCRENDINVPIIPGLKP
ISTLGQVTALPKIFHIDLPDELTDALSHAKTNAEAKEIGTAAMIKQCKELIEFGAPVLHF
YTMGKPDQTKEIAKAVF
>A0A1W9SRA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium 4572_128|TrEMBL
MKTILEKIKNRKKTLFSFEILPPLRGRNINSIYKIINTLNDFNPAFCSITYHREEIVYKK
LDNDFLQEKIVRKRPGTVAIAAAIQNKFPNLSVIPHIICGGFSDEETENALIDLHFLEIN
NLLALRGDSMKCENSFNPEKNGHKYSIELVKQIINLNKGKYLDNELENSEKTNFSVGVAA
YPEKHSEAPNLDFDLKFLRKKIDAGASFIITQMFYDNKKFFYFVKKCRDIGIKVPIIPGL
KPISTKKQISIIPHIFNIDIPEKLVNQVLKCKNNKEVRKIGINWAIEQSKELIDFGVPDL
HFCKKNF
>A0A3S1N6T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.09.1.1|TrEMBL
HLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGEPYRPHPGGYENGAELVAGLK
TIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRAITQFFFDNDLYERYVERVRR
AGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFEGLDKDPQTHALVASAVAAEQ
VMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAAGSAAA
>A0A497BTZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAKSSFEEKLDANEFVVTTEVGPPKGCDVSGLVHDIDLLKDKVDAINVTDHQSSVMRFPS
IGGCLLVKEQGGEPVLQVTCRDRNRLALQAELLFAHSRDIHNVLCLTGDSVDVGDHKEAK
PVFDLDSVQLLRTARLMETGTDTSGNELKGAPQFCLGASVHPGADFIEPQLIKFDKKVEA
GAKFFQTQGVFDLASLRRFMQYASQFDVKILAGIIVMASARMARYMNDNVPGITVPQPVI
DELATAEKGKGLQKGVEIAARFVKTIKEEKLCHGVHIMAVGNEKIVPDILERAELISVGA
>A0A535ALZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSTFTQLLRRGDFVVTAELNPPKSAAAQVVRRRASILKGYVDAVNVTDSNRAVAAMAAIP
AAVIAREAGVDPIVQITGRDRNRIALQADVLGAAALGIEHFVFMSGDDPKQGNHPDAVNV
KDLDGIGLVKMAASLRDKAQFLSGDEIKEPPQYTIGATASPFTKPMESDLRKTTEKIAAG
ADFLQTQPVFDLATFSQWLAEVRRLAGRHVAILAGVLVLRGAEQAERLAKVPGLALGTHV
VERMRAAEDQEGEGIAIAVETAKSLRSLPGVNGIHLYAIEWPQGVTKVVRAAGLYPRPLL
KESKSA
>A0A2V2A834|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter immobilis|TrEMBL
MTKPAFSFEFFPAKTELGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRNRTLDIVQALCA
RGDTDIAPHISCIGDDKAEIAELLDLYKGLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFAFDVDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTVAQPLIAGIMPITNSSNLVRFADSCGADIPRYVRKQLSDFGDDRKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLIEALGLA
>A0A2W1AG28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTNKPVSNLAQRLEKGLFTVTAEVTLPDSIEKEALVARAKMLEPYCDAINITDSTGAVPH
FSNIAAASILIENDIEPIIQFSCRDRNRIAVQADVIGAHAMGVRNIFCVTGDGVQTGDHP
EAKPVFDLDSVTLLTTINHLKTKGKFLSGRELDAKPDLYLGAAVNPFVPPFEQRALRLLK
KQKAGASFFQSQYCFDIERFETFLDRLMELTKGSPPPLLVGVGPLRSARFARWLRENVPG
VAVPDSIIEKIEKYPRKEQQKAGVEACIEIVETIKTLTGVAGIHVMAYNWESSVSEIIEA
TGLSKTARNI
>A0A2E6J7U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSKLSTKLKSGKFAVTCELNPPKGTDLEKLFKKAXMLKDRVVAINITDSAGSNMTMAPIA
VSHFLNHRGIEPILQITGRDRNRIAIQADLIAASALGITNILTMSGDPPQHGDHPEAKPV
FDLNSTQVLDAMKSMQGGKDLGENVLEGNPEFFRGAVVNPGAKDLESEFAKMEEKVSSGA
QFFQTQAIFEPDALEEFMVTAKKFDVPILAGIIVLKSTKMANYLNSYLPGISIPDNIIKS
LDLNDREAIKKESVSITSNIIKEIQGMCDGVHVMAIGWENTIPDILDQSNIRN
>A0A536S6N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGTQSEGRSLAALLRNPRYEIFPTDDVLDVVARHVPKEVTITVTASPRRGLPATVQLAIR
LARLGYTVIPHLSARLIRDRAELGQILDAIRPAGIRGIFVVAGDAREPAGEFPDTLSLLS
ALPPDHGLAEIGVTGYPESHPFIHDDVTIQAMWDKRRFATYIVSNMSFDPETVKRWVERV
RRRGVELPIYVGMAGVADPARLLRLSTKIGVADSARFLRGHPSWLARMFRPGGYEPGRFV
NALMPELTQAGRHMAGLHVFTFNEIEPTERWRQEMLARLQ
>A0A399ZM75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSILQRPLYANSRLERVLRSGRFAVTAELNAPDSADPEDVYRNALVLAEVCDAINATDGS
GANCHMSSLGCCALLVRAGYEPVLQVSCRDRNRIAIQGDLLGAAALGVKNVLCLTGDDVT
AGDQPQAKRVFDFDSIQLLNTARVMRDHGVFLSGRKLTTPPRLFLGAVENPFAPPFDFRP
LRLGKKVEAGADFIQTQYCFDVPRLVQFMRRVRDLG
>A0A7X9AC13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MRVCEILKQANKPLFTFELVPPLKGGNAQQIMETVRTLSEFEPAYINVTNHREEVTYIER
PDGLLERRTVRKRPGTIALSALIQYTFNIPVVTHLICGGSTADQIENDLVELHFLGLENV
LALRGDPAAGTKRFVPTSGGYTYSSELVEQIVNLNDGIYLDPTLKNAQKTNFCIGVAGYP
EKHGEAPNLEEDIAMLKQKVDSGAHYIVTQMFFDNEVFFRFVDRCRAAGITVPIIPGLKP
IGSRRDLATIPQTFHV
>A0A3A6NDI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp|TrEMBL
MVFVKPPFLEYLRDHVVLADGALGSYLYERGVERGRNLDLLNLQAPDLVFSAHEEYIRAG
SQLIETNTFGANLFKLREAGVEEQVREVNRAGAVVAVKAAGHQVYVAGSVGPSGIKFPLD
EAEVSADDISHAFQEQMAGLVEGGVDLLIVETFSSLEEVLLAIRAARAVAPALPLVAQMV
FPARGMTVRGKDAFSCGKAMAEAGADVVGTNCGRGIDAMVTAVGLMMPLASEGILLSAFP
NAGMPEMVGDRMIYPAQPAYMAARVGEMIKLGVHLIGGCCGTNPAHIEEFRSRLKIRPVR
IRGESQAEPRESVPHREVEDRPGGFLAGLKPGRLPIIVELDPPTHLDVEPVLVGAEELAK
AGADAISLGENPLAILRTGNLGVATLMRRRTGIQTIIHQTGRDLNALGLQSRMMEAHLLG
IEAVLAVSGDSASATDQPGVSGVFDLRSYGLLRMLRNLNNGLNLAGRSIKQQTNFSVGAA
FSFRAESPGLQIQRLEKKAELGARFAMTQPLFTREAVERMIEMTRHIDILIFPGIFPVIS
ARNADFLHNEVPGISVPGELRRLLAAYEQAADQRKAALEYTRQLVESIAPVVDGLYFVSP
LNKWEIALEFVRQVRAGNCRGSGRADRLCESRSTN
>A0A7Y3LV84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S3(2020)|TrEMBL
MALGIPSTRADSAASIHNLLARGGRSYSFEFMPPRSEAAEAGLWTAIRKLEALSPTFVSV
TYGAGGSTRGRTIDVTGRIAQETTLTPVAHLTAVEHSVGELRNILGHYADQGVRNILALR
GDPPGDPLGPWTEHPRGVRYAAELVSLIKESGNFCVGVAAFPEMHPRSSDWDSDMRHFVD
KCRAGADYAITQMFFDVEDYLRYRDRVTAAGCAIPIIPEIMPVTTIRSLRRIPSLSTAVV
PERLAERMLAVEDDPKAVRSLGIDHATEMCRRLLAEDAPGLHFMTMNFSTVTTEIYQNLG
LHE
>A0A8D4UUH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dialister hominis|TrEMBL
MTTLRAKNKNHIFTITAELDPPKSASSEITEKQVAEIADYVDAVNIADCPMAKLRMSPIA
LSSIIQQKYCVESIFHLTCRDRNTIGLQAELLGAYALGVHNILTLTGDPPSIGDHPDATG
VFDVDSTGLIEIARRLNEGHDLKGNPLGAATNFYIGTTANPGADDLDKEILRLEGKKKAG
AQFIQTQPVYEISQAEKFLSYAKDLDLPILFGIVPLKSFKMANYLNDKVPGISIPQRILK
EMETGNRETGLKLASELVQGLKDIGTDGVHLMPVNDVDAVPVIVKNLK
>A0A6G8RU47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter shaoyimingii|TrEMBL
MSKRIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSAIHDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYASDLVS
FIRQHSGDHFHIEVAAYPEMHPQSESFDKDIQNFVTKVKAGANAALTQFFFNPDAYFYFV
ERIQKEGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A432Q8Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp|TrEMBL
MPADSLFGNSLTNPQDFTITYELVPGQGAGGKKVDQLLDFASAAKKDGRISALSVTDNAG
GHPALAPVAIGTEIKNIGLDPLIHFSLKDKNRNQVESHLFLYQRQQFNYLLVLGGDFPKT
SYCGQAKPVYDLDTIQTIELVEHIKAGRYRCAGNTTQASQPFDFQCGCVVSPFKMTEAEQ
VWQYAKLLKKIRAGASFIITQLGFDLDKYAELITFLKDNNINLPILANVFVPTPAVAKIM
AKGGVPGVLLPHELAEKIASESKEQRLVRAASMTAVLRGLGYSGVHLGGSGLSFANVSSL
LDRAEGLKNNWQNIWEQAHFPCRGIWSLYRKTTPPEQHALNPGTRPGGKKLSELTHGLLF
DSRHASARLFGRLCIYADSSRLSRSFLTVAERIIKDILFSCRMCGDCTLSDSTYLCPQSG
CPKKLVNGPCGGSNNSRCEVFPDRRCFYVRVYMRCDRKTTISSLAAKPILQPKNWALEQE
SSWINHFRQKGRHCPETDSKPPQA
>A0A7X9IQH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MKLIDKIKEKQIISIEILPPDRGQNLEKIFEVIDQLLVYPIDFISVTRHPPVNSYIETED
RIIKADKIERPGSIGTTVALKNRYKIDVIPHILSSFMDKFQIEDLLIDLNLIGIENLFVV
RGDLKKENVIARNGDFNYHQNSAGLVSQIKEMNNGRYLYQSVKTSATDFCIGVAGYPEKH
YESPNLYEDLKYLKGKVDSGADFIITQMVFDLKVVKNFIQKLKKLSINVPIIIGIKPIVS
LKSIYDLPKRFFINIPENFIKKMQQAKSKEEEFKIGIKYMANYIKKLLELKVDGIHIFTM
GKGESTKALLKEIYY
>A0A3S2VJ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. San01|TrEMBL
MALGTPSTRTDRARTVRDMLATGKTTFSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVSDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMAEWIAHPEGLTYAAELVQLIKESGDFCVGVAAFPAMHPRSADWDSDVRHFVD
KCRAGADYAITQMFFYPEEYLRLRDKVAAAGCDTPVIPEIMPVTSVRMLERLPKLSNASF
PPALKERILTAKDDPAAVRSIGIEFATEFCAKLLDEGVPGLHFITLNNSTATLEIYENLG
LHDQRA
>A0A0P6VQ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQEH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCSRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHSDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRIGVEIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1Y4L4G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoflavonifractor sp. An184|TrEMBL
MKIAQLFGKGKTVFSCEVFPPKKTSPVDSIYKTLDGLKDIHPDFISVTFGAGGSSNVNQS
TAEIASIIQNQYHITAMAHLTCVGCTKGEATEILAQLKNSGVENVLALRGDRNPDFPPKE
DFLHANELVSFIHRRGDFGVSAACYPEGHPESPDLITDVRYLKQKVDAGAQHLVSQLFFD
NDDFFRFLERCRIAGIEVPIEAGIMPVLNRSSIERMVSLCGASMPRKLTRILARYGDHPA
ALREAGMAYAIDQIADLMAAGVDGIHLYTMNNPAVAKQISASIASIRNV
>A0A2W4TST0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya foveolarum|TrEMBL
MNAALNGQAGSPIAIAPQHRLRTAARSGEFIVTAEVMPPKGGDPSHMLEMAGHLKDWVHA
VNVTDGSRAVLRMSALACSVLLKQAGVEPICQMTGRDRNAIALQADLMGAHALGLNNILT
LTGDPIKAGDHPKGKSVHELDSIRMLRLIRQLNSGVDLNEKHMSDGALDIFAGAAVDPQS
RSWSGLQSRFEKKMEAGAQFFQSQLISDFDKLEKFMDQIAVGCDRPILAGIFLLKSAKNA
AFINRCVPGVDIPQHIIDRLEAADEPLREGMKIAAEQVQAARQLCQGVHMMAVRREDLIP
EILEMAGVEPQTLQQKVSALSAV
>A0A1G5EPT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoluna spongiiphila|TrEMBL
MRVTHLYESPSPVLSMEFFPPRTEKAEEGFGAVVDDLFSMAPDYMSVTFGAGGSNRDGSY
QTVRTMLDKSIPTVAYLAGYGMAPSEITEVLDRYRDMGIETLFVIRGDKPRQDGFTPHPD
SFSYASDLIAFIKKHYDFTLGCAGYPEGHQEAESLSKDIEYLKAKVDNGAEYVVAQNFYD
NAYYADYVDRCRAAGITVPIIPGIMPVYSVKMARILAKVCGTTITPELETRLTTVDPDDK
EAVLAMGIDFATDQCRGLLKAGAPGIHLYTMDRTFSTTEVVKRLRDEKLI
>I1CMT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)|TrEMBL
MERMQRYGPEFIDITWGAGGSSAELTTEIVATSQSVYGLETMMHLTCTNMPVEKIDKALE
AAKKCGCQNILALRGDPPKGQLNWESCENGFQYAIDLVRYIRQKYGDYFCIAVAGHPEGH
IDNPDKQDDLQRLKEKVDAGADLIITQLFFDVDVFVQFVRKCREIGIQCPILPGLFPIQS
YSGLSRVISFNNNHVPQKIWDDLETIKEDDQAVKDYGIHLAIQFVKQIKKETGISGFHIY
TFNLERSSRLILERLGLVPQLEYVKPLPWNPSLGPKRTKETVRPIFWKNRTHSYIQRTES
WDEFPNGRWGDARSPAFGEFDRWGVSIKYPVDKQLAMWGTPQSVDDIALLFARYCKGRLE
ALPWSAQRLDPETETIRQRLAAINLMGYLTINSQPAVNGAKSSDPVYGWGPKNGYVYQKA
YIEFFVSPEQLNELIVSMDQDPEITYFAVNHKGDLKTNTPDSDPNAVTWGVFPAKEIIQP
TIVESTAFMAWKDEAFELWNEWARIYDRQSTPAKLILDIHQHWYLVNIVHNDFQNENGIW
HLFDLEIDGDLSRKLRRASGSL
>A0A1C5WY36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MNLREYLKTTNLITDGAFGIYFAAKYQTQDIPELANITATEKVKKIHEEYLNAGAKFIRT
NTFASNKETLQEDFAEVEKNIQAAVEIARDAVNGRDAWIAGDIGPIPVNGAEDAAAAADE
YYQIAKTFAERGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGRPVDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIGELSSWDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLNVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNLLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTKEDAARLRRIKEETGATILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>A0A7C3PG51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillatoriales cyanobacterium SpSt-418|TrEMBL
MVFAPNRFQTAIQSGEFLITAEVAPPKGGDPTHMIRMAETLKGRVHAVNITDGSRAVLRM
SSLAASVILLQQGIEPICQVACRDRNVVGLQADLMGAQALGIRNVLALTGDPLKAGDHPN
ARSVFDVESVRLLQLIGKLNAGFDFNDKPLTDGATELFVGAAIDPQCPSWSGLQRRFERK
LTAGAQFFQSQLISDFDKLEKFMTQIATGCDKPILAGIFLLKSAKNALFIRRNVPGVHIP
DAIIERLERASDPLQEGMVIAAEQVRLARDLCQGVHMMAVKREDLIPKILDLAGLPPI
>A0A5C7GK07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Seonamhaeicola maritimus|TrEMBL
MKVTDHIKEANGKTLFSFEVIPPKKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYID
KGNGLLDKRITRMRPGTVGICASIMHKYNVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKDEAYFKPVKGGNAFASELVEQIAKLNRGLYLHDDVDVEHHSDFCIGVAGY
PEKHMEAPSLVTDLKRLKEKVDRGADYVVTQMFFDNSKYFEFVEKAKEMGINVPIIPGIK
PIAVKRHLQLLPQVFKIDLPQDLIDAVEDCKDNKAVRQVGIEFAIQQSKELKEAGVPVLH
YYSMGKSDNIHAIASAMF
>A0A8G1YT80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus equorum subsp. equorum|TrEMBL
MSQLIDKLKNNILVADGAIGTILYSEGLDTCPEAYNLTHPEKVAHIHRSYIEAGADIIQT
NTYGANFEKLKDFGLEHKVKEIHQSAVKIAKEAAKDDTFILGTVGGFRGVKQEDLGLSAI
QYHTEIQVDTLVESGVDGLLFETYYDLEELTNIIKATKRKHNIPIIAQLTALNTNYLRDG
TEINTALQQVAASGADIVGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSQF
KYSDNAEYFGNVAQKLINEGVRVIGGCCGTTPEHIEFIKSSIDNLKPVTQKNVIPITKYT
STSSKSKQSQNLTSKVKQRPTIIVELDTPKHLDTDTFFRNIKKLDDANIDAVTLADNSLA
TVRISNVAAASIIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLLDINEILTITGDPSKI
GNLPGATNVYDVNSKGLTEIASRFNQGINTDGDALKTKTNFNIAGAFDPNVRKLDGAVKR
LEKKLESGMHYFITQPVYSTEKIKEVYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEEVLEQFEAVKDDKEKSKELSLKLSKELIDTVHEYFNGLYLITPFQKADYTLELAAY
SKSITSTKQEAIL
>A0A7L3G612|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anhinga rufa|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGAVHGLHFYTLNREVATTEVLKRLGIWNEDPR
>A0A4U8UN12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steinernema carpocapsae|TrEMBL
MVIQGVQQRAMVLDTTVTIENGFTTGASVKGIAHANEYVPLHQRIEKHIASGTPFFSLEF
FPPKTVNGVANFFTRLDRLREGGPLFVDITWHLGSDPANKNKETSSTSIASACLDLCRLD
TMLHLTCAQYTKQQTLEHLNQCKSLGLRNVFALRGDLPKHDNNPVVYQHRALDLIKWIRK
EHGDHFSIGASGYPSGHPEAESYQHDLLYLKAKVDAGAQFVITQLFFDADVFERFVHDCR
AIGITVPIIPGIMPIQGYESIRRIADLSNLTIPDIIMKTLEPIKHDDEAVRNYGTYLATQ
MCRQILNNGTAPSLHIYTMNREGNCREILQNLGLWMQQPQRSLPWMPHGGHHPIRCKEDV
RPIFWSARPKSYIFRTKDWDQYPNGRWGNSSSPAFNDLQDYYLFYLKGTPTDDHMLDMYG
RQLNSVDDVRKVFVNFITQEENENRVKVTRLPWNEQESGTLPETTLIQEQLLWCNKNGIF
TINSQPAVNGAPSADPIVGWGKPGGYCYQKAYLEFFIEKAKAEQLKKVIEKEGYSHLSYH
MINYNSTVEWTNGDSTTPIAVTWGVFPGCEIAQPTVVDPLSFRVWKDEAYDAWLSTWAAI
YPEGSISTKILQEVHDNYYLVTVVDNDYVKDTVIFEALAKAVEP
>A0A1C6GDI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKLSELLSRGRPTVSCELFPPKVGTTLDQVEGVLRDTAALRPDFISVTYGAGGSTSKRTQ
EIAVRLQDTYHVPALAHLTCVSSTREEISSMVAALRAAGIENILALRGDIPQDADFPSPE
HYHYASELIGHIRSLEGGKELCIGAACYPEGHVECPHREDDIDFLKRKVDMGVDFLTTQM
FFDNDVLYRFLYRVLAKGITVPVIAGIMPVMSVKQIRRSCELSGTVMPPRLQGIADRFGD
DPAAMRQAGIAYATEQIVDLVAHGVEHIHIYTMNKPDVAARIMANLSDIIRPRG
>W0DTM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomicrospira aerophila AL3|TrEMBL
MKSQQKYPQGFSLECFPPRTAEGSDKLNQVIDELSVLNPEYISVTYGAGGTTQEKTLETV
THIQQNTRFDAVPHLTCIGATKDSIRALLKTYQDLGIKRIVALRGDMPSGMMDPGEFKYA
ADLVAFIRQETGDQFILEVAAYPETHPQARNCDQGIKHFKHKVDQGADAAITQYFFNADS
YFYFIDSCEKAGIDLPIVPGIMPITNYEQLIRFSAMCGAEVPRWLKCRLESFDEDTAGLR
AFGQDYVTRLCQRLLDNGAPGLHFYSMNKTQPTLDIVRDLNWRNDNMQL
>A0A1L3STP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquibium oceanicum|TrEMBL
MNQYRFSRRPDIGDKIAVSFEFFPPKTDAMEAKLWETTMRLQPLAPSFVSVTYGAGGSTR
ERTARTVGRMVRDTRLRPAAHLTCVDATRDEVDEVIREFLGMGVTRFVALRGDPAEGVGA
RYRPHPGGYANAAELVAALREKGASDISVSAYPEKHPESPDFATDIDMLKRKVDSGATRA
ITQFFFDNDSYERYVERVRRAGIYVPIVPGILPVHNFTQVANFSARCGAHVPAWLAERFD
GLHDDPQTHALVAAAVAAEQVLDLVERGITDFHFYTMNRADLVFAICHMIGIRSAEPLHE
VKPAAA
>A0A1I7EI08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia aspalathi|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRGQLASLKPKFVSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFAHKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTDLCGRLIEAKVPGLHFYTLNGAAATKAICERLGA
>A1C4Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMEQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCLGVAAYPEGHPVDSFQDVQDPVRDIPYL
VEKTQAGADFIMTQLTYDVEAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVQVPPHILSKLEAVRHDDDAVKRIGVDVITNLVDGIRKIPNPGFRGFHFYTLNLEKT
VSFIIERCGLIPDDAENSAAVDEDDYATVPSGAQLRALTRRRASSVHSQAHNRVIVDKLQ
KPSDGSSRASTTHEALANSAGMPAMAPDRNTTLQISEGLGALGREATWDDFPNGRWGDAR
SPAFGEIDGYGPSLHVSPTVARRVWGYPVSRDDISTLFRRHVSGELYIVPWSEGGAEENT
SGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRSDNSTFGWGPPGEGFVFQKPFVEF
FCPSKDFETVLKPLFANHGHEKLAWFATNAKGEFQSSLPAETADSDALEPNPDNVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAYRIWEEWRRIYPRGSATERFIDETKNDVWLVCVV
GQDFGAGTETGSDEEQHETKWMWNVLINSQ
>I0WKI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Imtechella halotolerans K1|TrEMBL
MKVTDHIGKAKGETLFSFEIIPPQKGKSIKELYDNIDPLMEFKPPFIDVTTSREEYIYLD
KGGLLDKKLTRMRPGTVGICASIKHKYNVDAIPHVLCGGFTKEETEYMLVDCHYLGIDNV
MALRGDAMKEERYFEPTIGGHAFATELVSQIADLNKGKYLHDVIETDNYSNFCIGVAGYP
EKHMEAPSLQSDLRRLKEKVDAGAHYVVTQMFFDNNRFFEFVEKAREIGITVPIIPGIKP
IAVKKHLQLLPQVFKIDLPEILVHEVEKCKTNSEVRQVGVEWAIKQSKELKEAGVPVLHY
YSMGKSENIRSIAQAVF
>A0A2D7E564|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula sp|TrEMBL
MSLASHFATSRCAISFELFPPKTEAGLQTLCDNVTRLKQFDPAFFTCTYGAGGSTQGATL
DVLQKVRELTDLPVASHLTCVNSTVADLEAFLHQAKQRGIDYIVALRGDPPHGTAEFQAV
DGGLQYANELVELIRDQFDFGIAVAGYPEVHQEAPDAQTDLDNLKRKVDAGADVIITQLF
YDNVNYFQFRDRCHAAGITIPIVPGILPVTNFKQATRIASMCKATIPTELTSLMTATDDP
AEQFQIGVEHARAQTLDLISNQVPGIHYYVLNKSDAAAALLDGMQTSQST
>A0A6J6BQ43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSDYLRTTTFSLEFFPPKDSAGEDRLWQALAQLQPLKPDFVSVTYGAGGSNRDRTIRVTT
EITKRTSIPTVAHLSCVGASKSDLTEILNQYMNAEIKSILAVRGDPEGGPKAKWEKVSGG
FDYADQLVELAVATGNFEVGVAAFPDGHPASNFDFEKDVDVLIRKEELGAKFATTQFFFE
SSKWHQLVERLAKRGSTLPIIAGILPITNLSQLNRMTELSGVQIPKKISKRFEGVENSSE
DVRKIGIEIATELGQELIDLQVPGVHFYTMNSAESTLEIAKNLGLVS
>A0A6J7PZJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MAFARRGGSLALRSKVSRLLGEGGHSISFEFFPPKDSDAEDALWGALIQLEDFDPSFVSV
TYGAGGSTRDRTIDITSSIGRRTSLTTIAHLTCVGSSRAELHEVIDGYSEAGIENVLALR
GDPEGGLGVPWVSHPDGLDHAIQLVEMLRERGDFCVGVAAFPEGHPESASLEQDARVLAD
KQRAGAEFAITQFFFRADDWFGLRDRAEAAGCTMPILPGIMPVTNLAQIKRFSALSGAEF
PAALAARFETVADDPAAVRALGVEVATQLCEALLDGGAPGLHFYTLNRSSATREVYRNLM
GRPDLERH
>A0A7J4I0T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon|TrEMBL
MKLTDILKEKKNIVSVEVEPPLLGKGINSLWEMLDPLARLGISWVDITYHAEDIVGYEEG
NDNGSGNGSNGLVPVFERKKPGTGAIAGAIMQRYRDQRMEAVPHVICSGFTARQTEEFLV
EVSYQGVTNVLAVRGDPPKGPDGKRLEFAPVKGGHTHASELVQQIVGLREGHYLGAREGE
PLDFCVGGACYPEGLAGESIKRQLEWLKYKIDQGIEYLVTTMFFENAKYFQFRDRAYAAG
IRVPIIPGITPLSKVGQLESMPSMFGCTIPRGYREVIKLHQDELGEEEVKKTGIDWCARQ
CRELRRQGAPSLHFYANRNAPVAEVIELITPTSM
>A0A6G0XXW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces euteiches|TrEMBL
MGKIIDRLKELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGAHIQNEFKIDVLMHLTCHLPRDQLREILKNVRAAGIRNILALRGDPPIGSE
RWKPVPGGFHNAVELIRFIREEHGDWFCIAAAGYAEVHTEAWNNPNLPPSDQVRELDMIR
LKEKQDAGADFIITQFFFDVDKLLQWVQDCRRLGIKIPILPGYLPIQTYNSFLKFTNWCK
TSVPMQVEDDLAAIKNDDAAVKKYGIHLAIDTCRKLLANNLSLHFYTMNLASTVRSVLEG
LKLIDRERGLPWGVPITRSKDGKLEKNIEQVRPIFWSNRASSYIARTSEWDDFPNGRWGD
RTSPAYGELSEYYLAFKRPKVARDVLWGRPLTEQDVWSVFVKFIEGSVKQLPWCEQGLSG
ESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKGGFVFQKAYVEFFVPPRLM
QRLVTALADYPNLSYHAFSANGTEYTNSPGPSVTAVTWGVFPGKEIIQPTVVDTASFAAW
KDEAFELWLSQWASAYETDSPSHQLIKQIYDSYVLVNIVDNDYTNEDSDIFKIFARVITE
SMTKDDLRQRVLELEGRNEKLHETVAKLKIIQAEANRELKDLHTELSTSREENSRLKAQL
RDLRSRLAMAEL
>A0A7S3TIM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emiliania huxleyi|TrEMBL
GEPFVVADLGVAAGANAVSVARLVISEFMGRRPGEAISYAFEDLPLNDWTVLAQTVSAAE
LPCFTSFVPRSFYEPLFPPASLSLSLSFITLHWLSEAPRLSADAVLAMERHTAADVAAEW
RDQAHVDLVSFLRLRATELKDGGEGVYLMVGGGAALPVHEWARPPSGGPSIFSVALSRAV
AAGDIDEAAAMAASVAYHLRTDDEVRRAAGEVGASLELLDVTSAEVRVAEGRSAEEHADL
AWAIHSNSILSSSGIGDEAGERVRLHLRDVVATEFGDSGATISYVSLAVRRRPREANAAS
EEGAVAPASEAVATAALESRRLPRAAPAGCSYSQRGWDPMWLARALADPARPTFLFGSTP
PRDGTTAAEAAQICAKFVARSRAHASDGFIVYDIQDESSRNAESRPFPFRRTIDPSEYAQ
HFPPASGKSTVLYKACSEADEAAFASWLDGAQRRNHHTLNLVGPSSSGDTPRISMERAAA
LVNERPGMAFGCVTIAERHLTKGTEHLNLLRKAGYGAKWFISQAVYDAEATIKLLHDYAG
ECRRRGCTPVKILLTFAPVGRPKTLQFVKWLGVHVPSAVEERILAKANATESKTKEAAVL
ESIDVCCEALQRILQMAGGCGVPLGLSVESLSGFREEIDGCFELFRRLQATMLDSVCSPW
AVRWYRVPVHSMARSHSEEQLAADAGPEMAEEEQAAGSI
>A0A6J7BU24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MKQLNRMVELSGMKVPTAIADQFNKYADDLEATKEIGIEIATNLGAQLLKRGVPGLHFYT
MNSAQSTVAIAKNLGLIK
>A0A6J7GJ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTIPFSFEVYPPRKPEHQAALHETIQKLATAGPDFITVTYGANGSSRDASLDCLRFIREH
TDVAPLAHVTCVGSTRDEMNALIDEFLAADIRMFLALRGDPPEGADPQSDYLGDVKTAAE
LVHLIRERGDNDLSIAVAAFPNGHPMSTSPSSDIDILLAKQAAGAEFAITQLFFNATDYL
SFLSSARAAGVTIPILPGIMPVTSLSRLRHIVEITGERMPRDLEAALEAAPSPAHARTVG
VAQAVELCRQLVAGGAPGLHLYAFNEHETVLEVLAQLNEPA
>A0A6J6M045|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARIGDLLATGRTFSFEFSPPKSAAGSLSLGRTIAELEPLAPSFVSVTYGAGGSTREHTR
DTVLWVRKETNIPPMAHLTCVGHTRAEIADIISTYTDAGIVNVLALAGDAPKDPADARPS
DYVYAIDLIEHLKEIGDLCIGVAAHPEGHPRSPDLATDRQHLADKLRAADFATTQFFFDL
DHYLSLVNDLADLGVTKPVVPGIMPVTNIAQVERMAELSGAAFPAWLRERLESGTSPEDV
RRIGVEAATELSAQLLEAGAPGLHFYTMNKSTATLEIYAQLGLPVV
>A0A8D4VRV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylogaea oryzae|TrEMBL
MNHKFSFEFFPPRDDEAAARLRQTYQRLAALKPEFFSVTFGAGGSTQEKTVETVCDILQH
TGIEAAPHLSCIGSRRDGIRAILDDYRQKGVKRIVALRGDLPSGMLATGEFRYANELVEF
IRRETGDHFHIEVAAYPEVHPQAANAETDLLNFKRKVDAGADEALTQYFYNADAYFNFVE
RAHKAGVDIPIMPGIMPITNYSQLARFSEACGAEIPRWVRKQLECYGDDRDAIRAFGLEV
VSDLCRRLLEGGVPGLHFYTMNQADTMLALWKNLGLPAPQ
>A0A6A6I6Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trematosphaeria pertusa|TrEMBL
MEKVTDKIKALPDGANYFSLEFFPPKTSMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRSLIDEALEQAKVLGMRNILALRGDAPRSKE
YREEGQLPEEDSNNDFTWAIDLVRYIRRQYGDYFCIGVAAYPEGHSDESHPEHQSLEHDL
PYLVEKTKAGVDFIMTQLFFDVEAYDKFEKVLRDHESGAFKTIPIIPGLLPIQSYQILRR
VTKLSHAKLPADMLARLDAVKGDDELVKQVGVKVLDEVVEHLKRNAGPGKRGFHFYTLNL
EKVVSHILEDCHLIPQPLVDEDEEAIETTPAINISPPNGAMANHERRRLSSFNSSPHNRV
IIPRPSVSKSSHSYETTETEAGIPKEPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVDKDDISNIFKRHIEGDLDAIPWSEQGLSP
ETSTISKELLALNAKGWWTVASQPAVNGVKSTDPVFGWGPRNGFVFQKPFVEFFIPSADW
KQLQPRLKAHNQITYFAGNANGDFEASSEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWM
EEAYSIWREWQRIYPPKSATSRLLGELREDVWLVNVIWGDFVEGDGLWEFLTE
>A0A6J6KE38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MNSKLRGTTFSLEFFPPKDEAGESRLWLALSQLQPLAPDFVSVTYGAGGSTRDRTIRVTS
EITKRTSIPTVAHLTCVGATRDELVEILNQFKNSGIDSILALRGDPTGGPTAPWQMIPNG
LNYAKELVELAVGMGFKAGVGAYPDGHPASNHDLAKDIEVLLAKEKAGATFATTQFFFEI
DKWQAIVDKLAKAGSKLPVLAGILPITNVKQLNRMVELSGMKVPTAIADQFNKYADDLEA
TKEIGIEIATNLGAQLLKRGVPGLHFYTMNSAQSTVAIAKNLGLIK
>A0A7J9Q527|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon|TrEMBL
KYGVDAVNIADNPLARTRMSPVTLAHLIKKKVGLEPILHFTCRDRNVLGIQSELLGAYAL
NIENVLALTGDPPAVGDYPYLTAVFEVTSKGLIHIIKTLNQGYDLAGNPISPHTNFCIGA
AVNPNASNLDREIERFKEKVEAGASFAQTQPLYDINIFKKFLDKISHLKIPILAGVLPLQ
NYRHAEFLHNEVSGIIIPEGIRERMRNADKPEKEGVLIAQEFLADAKKLVSGVCLMPPFE
RYDVALDVLRVLKEKRGRKK
>A0A6J7DJJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSDASVGIVDQALSNGRASISFELFPPKTAQGEKNLWEALHELDALTPTFVSVTYGAGGT
TRDLTVRITERIASQTSLSPVGHLTCVGATRDQVQGVIEQYRAAGVRTVLALRGDPPGGL
GTPWVQHEGGFKHADELVAMLASYGDMSIGVGAFPDGHPESVSVQQDADVLAAKQAAGAH
FAITQFFFSADRYFESVELAKSAGCSMPIIPGIMPLTNFTQVQRFAELSGVQVPSELAKR
ARAVADDPEAVRELGIAEATRLCQQLLDGGAPGLHFYTLNRSSATREIYANLGLS
>A0A3N7DCU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. KBW03|TrEMBL
MKITEHIKKANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINNLGRGKYLHNEEQICDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFYDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINAVENAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKIAGELF
>A0A3D6BAK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriales bacterium|TrEMBL
MKVIEHLEKAKNPLISFELIPPKRGGDIKGLLSVLDDITKYNPPFIDITSHAAEVIYEET
ATGIKKKIKRKRPGTLGICALIQNKYNIDAVPHVLTKGFTREETEDFLIELNYLQIQNVL
AIRGDDSGYEKPIPEGKSKNPYASDLVKQIINMNHGKYLEDSLLDARPTDFCVGVSGYPE
KHFEAPNLKTDIKFVKEKVDAGADYVVTQMFYDNKYYFKFVEQCKEMGIKAPIIPGLKIL
TSKSHLSAVPKNFYISIPDELADEVMAAKSEHVLDIGVEWAAKQVEELLNNDVRSVHFYI
MQNSKPIIKLMERLKL
>A0A2T4FSY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aylmerensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMAVAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEANIPAAPHLSCVGDSKADLRGLLTQYQQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISSMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3N2PXC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sodiomyces alkalinus F11|TrEMBL
MEKITDKIAALPPGTDYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
ADKSLELAEICQRELGLTTCLHLTCTNMSRRMIDKALEDAKVLGIRNILALRGDPPRNAE
YRDSDDSDADDGEEFSWAIDLVEYIRKKHADYFCIGVAAYPEGHAAESHPLGQSLEHDLP
YLVDKTQAGADFIMTQLFFDIKAYENFERTLREHPSGAFKTIPIIPGLMPIQSYQMIKRT
TKLSHASIPDHIMARLDAVKGDDEKVKQVGVDILSELVEQVREVKGRRHGPRGFHFYTLN
LEKAVSFILERTHLIPDKDEENEEAVVDDEAQPPAPAPAPEPEPAAAATVPSVQINGLLE
TPRGDRSSRRLSSIGSDPRNHVIVSRASNPDYETTAALAGIPAEPVNTRANTLAISEGEG
ALGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSVTQAVRLWGHPTAPADISDLFIR
HVRGQLSAIPWSEEGLLPESNVIQDQLVQLNARGWWTVASQPAVNGVPSNHRTFGWGPRN
GFVFQKAFVEFFVPSADWARLSGTLRTDPAVCFYASNSAGEFESSDTSGGIAGQEATGAS
TNAVTWGVFPGKEIVTPTIIEEVSFRAWSDEAFKIWGEWARVYGKGHPSEAFLRRVRGDY
WLVNLIHHDFVEPNALWELLLKS
>A0A5Q4FP59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitriliruptor sp|TrEMBL
MDDLLARGRTTSFELFPPGTDEGEKILWRALDELEPLSPSFVSVTYGAGGSTRDRTHRLV
AELLRRTTLTPMAHLTSVNHTRDELATILERYRDAGVTNVMCLRGDPPKDDPDAFWELGH
ATDLVQLAREVGDGAFAVGVAAHPEGHPLAPDLATDRDHLARKLELADFGVTQFFFRASD
YRDMVADLAARGCTTPVLPGIMPITNVRQIVRFAELSGAEVPAELVARLREVEDDPAAVR
RLGVEVATDLCRELLDAGAPGLHFYTLNRSSATREIH
>A0A7W3TGK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces alkaliphilus|TrEMBL
MALGLPSVRTDRARTVRELLAAGERSYSFEFAAPRTERGEQILWEAIRRVEAVGPTFVSV
TYGAGGTSRDGTIRATERITSETTLTPVAHLTAVNHSVAELRNIIGRYADAGIRNLLALR
GDPPGDPMGEWVRHPEGVTYASELVELIKESGDFCVGVAAFPEMHPRSVDRETDIRHLVA
KCRAGADYAITQMFFRAEDYFRLRDRVAGAGCETPIIPEIMPVTSVKQIERFASLSNATF
PSELERRILAVADDPVAVRSIGIEYATELCAELMEQDIPGLHFITLNRSVATLDIYRNLG
LHRRSDR
>A0A7M3P5G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. uw30|TrEMBL
MTTTLREVLARDLAAGTPTFSFEFFAPKTESGTRNLWDAVRRIEPLSPTFVSVTYGAGGS
SKDRTVEVTGRISTQTTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDP
NGPWIPHLEGFTHAHELVSLVRDISDFSIGVAAFPERHPRSPDWESDIRHFVAKCRAGAD
YAITQMFFHAEDYLRLRDRVAAAGGTTPIIPEIMPATDVRQIRRFAQLSNASFPEDLAQR
LDAARDDPAEGHRIGVAHATEMAGRLLAEGAPGLHYITLNRSPAAFEIHRNLGLTRKAVP
AAA
>A0A0H3MZU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridioides difficile (strain CD196)|TrEMBL
MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAANVTDFQSAVMRATSLA
TCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLLALTGDHTSVGDHPQAKGV
FDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTPEYSPIEVQLLKMQKKIKAGA
KFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSPGMAKFMTANVPGIFVPDEQIER
LRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIMAIGAEENIPAILDAAGL
>C5FFF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthroderma otae (strain ATCC MYA-4605 / CBS 113480)|TrEMBL
MHIKDKLALAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMPREKVDEALQSAFKAGCTNILALRGDPPREKES
WEQTEGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFLDWVKRCRKAGITVPIIPGIMPISTYAAFIRRTNWVKCKIPKGWMEAL
EPVKNDDAAVKQIGRALVSEMCRKLLDNGINHLHFYTMNLAQSTTMVLEELNLKPSTETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSVKDLSDIFIRFLEGKLDRLPWSESAITQESDIIKDDLIA
LNNRGFLTINSQPAINGAKSSHPIYGWGPKNGYVYQKAYLELLISPTLIDEVIRRIETNP
DLTYHCINKNGELRTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKIIQNTMDTWYLFNIVNNDFHKTHDIFDLFKGLVLKDLDTEVSGTQPASE
PVKNGSHPGAPASTSENQAVAAN
>A0A529B034|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQIRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKREGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A528KDJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
VQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFLGAAINPFAPPIDF
RPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILCGVGPLASAKTAKW
IRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSGIHVMAYRQEEYVA
EIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVKTAH
>A0A4U6Q941|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nakamurella flava|TrEMBL
MTQDNPTRTAADLLTGASLEMTGKDAPGLQEAADLLQPGTRINVTYLGTEDDALRLDGVR
AVRQQGLVPVPHIAARRLRSVEGLAGYCRALAEADAIIEVLVVGGDPASPEGPFPDALSV
IRSGVLTESGVRGVGVTGYPDGHPAIRPEILWAALDAKVAEVAAQGLEGSINTQFGFDAT
TVLAWLEQVRERGIDVPVRVGIPGPAGVKRLLGYAKRFGVGTSTSILRKYGLSMANLMST
AGPDRFVNQLADRYDPARHGDVALHFYTFGGLRATAQWIQETRR
>A0A530M1K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRAYMQKVCDLGYTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDQIVKRLEGAQDQKREGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRRPWKREIRRDDQLVADRLDHILHDDLTETQVDMVK
TAH
>A0A1J5L9D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. MedPE-SWchi|TrEMBL
MGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLIAAPHLTCIDASREELIQIADDYWNNGIQSIVALRGD
IPPGGGAPDMYATDLVKLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIEVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQG
>A0A530AHN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTTLEPLKPELVGALKSVGDFDI
SVSAYPEKHPESPDFATDIDMLKRKVDNGATRAITQFFFDNDLYERYVERARRAGIYIPI
VPGILPVHNFTQVANFSSRCGALVPAWLAERFEGLENDPQTHALVASAVAAEQVLDLVER
GVGDFHFYTMNRADLVFAVCHMIGIRSHEAEATGSAAA
>A0A527HA27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETAIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGG
PYRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYVPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADL
>A0A441CY72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIQEFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A530BIR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
ARAPADPEDVYNRAKIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRD
KNRIAIQGDVLGGAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGK
FLSGRKLTTPPQVFLGCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQ
KARDLGHTEKLFLLCGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLC
IDIINEVKEIPGVAGIHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDH
ILHDEITETQVDMVKTAH
>A0A5F1EBZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E4930|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>K6H301|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR86 cluster bacterium SAR86E|TrEMBL
MKISYEFYPPKDLNFNKVVNEYLLIQGYDPSFVSITYGAMGSSQEKSVGLIKAFKNITDV
DVVAHLTLVGKSRDDLKKIIDEFKSLGIKKVVALRGDSPEGKFQAHPDGFYNTSDFVKFL
AGHELEVIVSAYPEPHPDSEGFAFDLRLLEEKTLAGSNQCITQFCFSTERYENLVTQISS
QKINNEITAGIMPIYNIDSLCNMAQRCGIKIPKEIIKQFSGNNNQNQRAAIDICIKQIHD
LQNMGINNFHFYTLNQSSLLKEIFDEIPIIN
>A0A517N279|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adhaeretor mobilis|TrEMBL
MSLSNTYGPGRFALSFELFPPKTDGGVRALAGHVRELMKFKPSYVTCTYGAGGSTQNRTL
EIIGDVRKQHGVAVATHLTCVGSTRDQLRDYLQRAQGLGIENVVALRGDPPQGETKFTPV
ADGFSYANELVAFIRGEFPEMGVLVAGYPETHQEAPSADADLENLKRKVDAGGDAIITQL
FYDNADFFRFREKCEELGITAPIIPGLLPVTNGAQIQRIASLCGAKLPSDFIAALEKYED
DPAGQFEVGVDFATKQSAELLEAGVPGIHYYVLNKSEATKRVLEAVEVPVGTPS
>A0A1X0W7R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rouxiella silvae|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPTFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATAAELRQIAQDYWQSGIRHIVALRGD
LPPNSGKPEMYATDLVHLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIVPGILPVSNFKQLQRFAKMTNVRVPNWMTSMFE
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGIPASL
AL
>K0V6L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium vaccae ATCC 25954|TrEMBL
MDVDCPKRMSYGPCGGVRPDGQCEMRPGPCAFPEVVPWPVLAPTPAPAAPVAAPLILTDF
TCTPFDPADIASTAAVLAPSCDAVLVGEHQNRPDFPPTLMGRMLLEAGVTPWITLSCRDR
NRVVLEQELRGLALTGVPTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVALAASLGMTAAA
PETVTAPPVHGRAQRLVQKQHAGARLAVLNHVSAPAAVAEFMSAARAAGLTIPVLAAVAV
FTDEVSAALLQGLPGLALDAGVVAQVLRAPDPVEAGIDAAVAEARALLAIDGVAGVNISG
LASDAGTRAGAWIKAEVGQRIREERSAV
>A0A1F1XDT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC05E07|TrEMBL
MSPRLSASAPLDQISEDTPERLERTALSFEVIPPRHDADAAKIDRLLATLSAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTSMRPLAHLACTAGTEQELEEWIDTLVDAGVRGLLALR
GDLPEGGMPEGHLPHADSLVRLIRRWESARVARLAAGRLAVGVACYPSGHAESATADEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTAVLDQFATATSPEEEQEIGMQITASLAQAVLNAGADGLHIYTHNNPDITTDLL
NRIGVTP
>A0A2N8KXZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paucibacter aquatile|TrEMBL
MSTATPRVPVSFEFFPPNTPVGTEKLKTVVQDLSVLNPHYFSVTYGAGGSTREKTLSTVM
DIAAAGYEAAPHLSCVGSTRENIAEILATYRAQNIRRVVALRGDLPSGTATAGEFRYASE
LVAFIRETQGPDWQIEVAAYPEYHPQQRYAAKDLQHFAAKMRAGANSAITQFFFNPDAYF
HFVDEVRKLGVDAPIVPGIMPFHNYARIAQFAARDGIEIPRWVALKMEGYMDDAASIREF
GLEVMTRVCERLIAGGAPSIHFYTLNQSTLTLALCKRLGLG
>A0A5P2G4K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachidicoccus sp. B3-10|TrEMBL
MKITEHIAQAKETLLSYEILPPLKGKDISSIYQHLDSLMEFKPSWINVTYHRVESVFKKL
PNGSFEKIQMRKRPGTVGICAALKNHYGVDAVPHIICGGFSKTETEDALIDLNFLGIDNV
LVLRGDAAKSDGTFIPEPDGNAHALDLLKQVADLNKGVYLNSEGIVNGFSTDFCMGVAGY
PEKHFEAPNLSTDLEYLKQKVDAGASYIMTQMFFNNAKYFEFVETCKSMGINVPIIPGLK
PITKKKQLSILPSIFHVDIPEAFSKELLKTKNDQEAEAVGVEWLIQQSKELKAAGVPVLH
YYTLGKPSTIKNVVKEIF
>A0A3M6EM14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. atropurpurea|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDGKDDLRSLLAQYREAGIKRIVALRGDLPSGMGMASGELRHANDL
VTFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A442NCB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MEKAAIRPSSIDASIEMAPSQVIDSPDLPGLFPSGVRVYITDIGLADTPTLVKAARRVAD
LGYTAVPHMAARRLTTRQALETRVKALAEESGVRDLLIIGGDVATPAGSFSSSFEVLETG
FVDKYGITEVGVAGHPEGSRDFGDEAAIAALRMKSAWAERTRAKMRVVTQFGFDADKFIA
WADGLAVSGVDLPIHLGVAGPAKITTLLKYAALCGVGNSLNFLKKRSASLAALATSHSPE
SFVSPIEHHLRAKPESAIAQLHVFPFGGIKNTARWLYERGSWQDLEADDRSSIA
>A0A1H7CDJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. NFR16|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARTLAGYNPDFFSCTYGAGGSTRDRTINTVLQLE
KEVNIPAAPHLSCVGDSKADLRGLLAQYKEAGINRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEEDLKNFVRKANAGADSAITQYFFNADSYFY
FVDRVEKLGVSIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDAASIQAFG
EQVITEMCDRLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A527TI30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDAVIREFVDFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>A0A2K5I299|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colobus angolensis palliatus|TrEMBL
MDHRKARVLPAGHYCPSLGTWASQAGSVRFSVPPSISRKLAMVNEARGNGSPNPCLEGSA
SSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDTLELLNRPTQNERETETP
>A0A2E8CK41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MPGMPLPILEGHASAGRLERVLRAGRFAVTTEIAPPDTADAQAVFERASVFDGSVDAINA
TDGSGANCHMSSVGVCALLTRRGYATVMQVSCRDRNRIAIQGDVLGAAAMGVTSILCLTG
DGVQAGDQPHAKPVFDFDCMSLLETVTVMRDQGEFLSGRKLNNPPRVFIGAAANPFAPPL
DYRPLRLKKKIDAGAQFVQTQYCFDLEQLKSYMVQVRDMGLTEQCYILVGVGPLASARTA
AWIRDNVPGVHIPDPVIRRLLGSENQREEGIRICVEMIQAIREIEGVHGVHIMAYRQEER
VSDIVRESGVLEGRMPWHPGLTQRLID
>A0A529N5Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
LVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHEAEAAGSAAA
>A0A0A6VAQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weizmannia ginsengihumi|TrEMBL
MGLIERLKNEILIADGAMGTLLYSYGIDFGYEELNVTNPSIIERIHRDYLEAGADIIQTN
TYSANAIKLARYGLETDVKKINNAAVSIAKKSISSSEQYVIGTLGGIRGIRKNSASMDEI
SAAFTQQLDILLEGNLDGFLLETYYDFEELTNVLKIARSMTDLPIIAQVSMHEPGFLQNG
LPLNSALEQLEILGADVIGANCHLGPYHTCQAFDQVTLPKKAFLSAYPNASLLDVVDERI
VYKSTADYFGKLAVELRNQGVRLIGGCCGTTPDHIAAVKRALKGLPPITEKEVEHPRESI
LIEDHAPVPPSLVEKVKKQRSVIVELDTTKHLETTTFFKGAKSLQEAGIDALTMADNSLA
SPRISNMAMATLLQTNHNIRPLVHITCRDRNIIGLQSHLMGLHTLGIHDILAITGDPSKI
GDFPGATSVYDVSSTELLQLIKQLNEGISFSGKPLKTKTNFTVAAAFNPNVRLLDRAVKR
LERKIKAGADYFISQPVFSIEKIEEMYEATKHLSTPIYIGILPLTSSRNAEFLHNEVPGI
QLSEEILMRMKAWEHDKVQAEREGIKIAKELIDVAARKFNGIYLITPFLRYHLTTELVTY
IHDLDATITKGDANDVQSISH
>A0A8H2RZE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MGLLKTAFDERTFVCVMEFVPKPSAERFAALESIMARTHLCGWPMTVSIGDRVGGPLDMS
PLDAFSSFTQDQPSLPHFSGKARERQDLLDQLPRMDAAGLDQLLILTGDRLPGHEPGQRP
VRYLESVAALQIVRQARPDWLLGAALNPFKYHEEDGGAQYFKAEKKLSAGADFMTLQLGY
DDRKHFEALQWMQRQPAPKPLIACLMALTHGRAGMLRHVAGVTVTPSMHDVLAAELAVSK
AHAQQRSLRRLAVQITGLKLMGYAGVHLSGVHDLGQFEALEREIVAAQAEIKTLDQWASA
WAASWRMPGLPAVTFNPPGANWRLGESHVSASTREKARYYLMSSMHSLVFDRRGLLGGAF
GWAVTRPVWSTATGARLLHGLERSIKRPMVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECVHSVKYRTAKAVGQSGVLTERLIASVDVHGRHRSSWPGWFDAG
>A0A7K8UBD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanites oceanicus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPDAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A8D0AR72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sander lucioperca|TrEMBL
MVNQVQRGDGSWQSCKSDSSGASNSSESSKESSRSSTPVLDVDRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGTGGPLFIDITWHPAGDPGSDKETSSLMIASTAV
NYCGLESILHLTCCNQTKEKISGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATD
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNY
GIKQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LKMWGDELMSEESVYEVFTCYITAQPNRSGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIAGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVN
YHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWKVIDDMFELLDATPEPASFVAITT
ATATVS
>A0A8D0AM43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sander lucioperca|TrEMBL
YNKFPSKLRISENTCVGVQRGDGSWQSCKSDSSGASNSSESSKESSRSSTPVLDVDRSDR
LRDKMRRRMESGDRWFSLEFFPPRTASGAVNLISRFDRMGTGGPLFIDITWHPAGDPGSD
KETSSLMIASTAVNYCGLESILHLTCCNQTKEKISGYLAKAKHLGLKNIMALRGDPVGAD
WEEEEGGFNYATDLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADF
IITQLFFRADTFLKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVI
EPIKDNDAAIRNYGIKQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPR
RPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYY
LFYLKSKSSKDALLKMWGDELMSEESVYEVFTCYITAQPNRSGHKVMCLPWNDEPLAPET
NLLKDELEKVNRRGVLTINSQPNINGKPSTDPIAGWGPAGGYVFQKAYLEFFTSSENVNA
LLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWK
DEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWKVIDDMFELKT
TRKMNCENEMYFKGYVHTWRLLYTRKS
>A0A167V8B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cordyceps fumosorosea (strain ARSEF 2679)|TrEMBL
MHVKDLLAETKRSGKPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPQFIDITWGAGGRVA
ELTCEMVLQAQAVYGLETCMHLTCTDMGMEKVNDALHKAYKAGCTNILALRGDPPRAQEK
WTATEDGFQYACDLVKHIRATYGDHFDIGVAGYPEGCDDNDDEDELIEHLKYKVDLGGTF
IVTQMFYDVDNFIRWVGKVRAAGITVPILPGIMPIATYASFLRRCKHTGCNIPQKWLDLL
EPVKNDDVSVREVGKKLVVEMCRKLMAAGIHHMHFYTMNLAQATRMVLEELSWTPSAERP
LQQALPWKPSKGFGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRLKWGEPKSLRDIANTFVRYLNQDIDSLPWSEAPLTSEADSIKPALIE
LNQRGFLTINSQPAVDGVKSSHPVHGWGPANGYVYQKGYIELLVSPEIVDQVIRLIDANP
SLTYYAVTKDGNLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFDAKSPSRVLVENVMDNWYLLNIVNNDFHDNTTIFELFKDLKVDGLDVPVTVEAEAV
AEAEAPAAIQAETAA
>A0A229W166|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium vansinderenii|TrEMBL
MHKPIFSIEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTQSDRTATARIAHTIR
SEYGIPTVAHLTALYSDHEVVDRALDMFDEAGVTAVLALRGDELPDHESVGVFPHASDLV
AYIRERRPSLKIFGACYPEGHYQAESLDKDIENLKIKVDAGATHLISQLFYDNEDFYRFL
DKARAAGINVPIEAGIMPVRGAKSVRRMAERNASRIPKPLEAILNRWEGNRDALHAAGIA
YASQQINDLVANGVDGIHLYSMNHPGTTRRIWNNVKPLFQKI
>A0A0M6ZW81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium alexandrii|TrEMBL
MTDSSLLANGRLPASTEMSPKQVVEKTELLATIPAGSQVYVTDLGNAPEDTIVAAAKTLT
DKGLIAVPHMAARRYASAADFERRITRLTQEAGVKEVLAIAGEADKAGPLTSSVALLETG
LFDKLGIQKIAVAGHPEGAPDIKPDVIKSFLMRKHELAAESDAEFRIVTQFGFDPHQVSV
WLDEIRGWGNQFPVHIGVAGPAKMTTLLKFAAFAGVENSLNFLKKRGGAVVSMLAGYDPN
TMVEPLEARITSQPDSQLAQIHVYPFGGVAKTAEWLTSRGSWSFQTSSTSLTANESA
>A0A0M8R4W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rimosus subsp. pseudoverticillatus|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVQHPEGVLYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATQLCARLMAEGSPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A2E7MYP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVTDYLKDENKTYFSFEIIPPFRGGSIDXIFSLVEELMKFEPPFIDLTSRSAEEYYQDD
GSGNLVQHIRRKRPGTIGISAAIKNKFNVETVPHLLCSGFSKEETEDALIELNYLGIKNV
LALRGDXLRKDRNEINSKISNXYASDLVKQIKNMNXGKYLEPLIDPTKSDFCVGVSGYPE
KHFEAIDFKTDIKYLKEKVENGADYIVTQMFFDNKVYFDFVERCRKEGINIPIIPGIKIL
STERHLTALPKHFYISLPQELKNSVEGKTKNEIRNSGKKWAINQIQELLEGSAPCIHLYI
MASAKLPSEVVSEFI
>D3IMQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. oral taxon 317 str. F0108|TrEMBL
MKVSDFLNKKAAAKAISFEVLPPLKGNGTAQLFRTIDRLREFCPSYINITTHNSEYVYRQ
LDNGQYERDRIRRRPGTIAIAAAIQQRYAIPVIPHIICSGATIESIEYELLDLQFLGIQN
LLLLRGDKARDDRMFTPTPNGHAHTTELIEQVNHFNEGFFADGTPMKHPGESFEYGVACY
PEKHEEAPNLDMDIDYLLRKQQLGAKYAVTQLFYDNQKYFDFVEKARQKGVTIPIVPGIK
PFAKLGQLTVIPRTFHCDLPTALASEIVKCKTDDDAKALGVEWATQQCRELYAKGVSSIH
FYTVSAVDSICEVAKKLL
>A0A3D2WWH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIEYLEKAQKPLISFEIIPPDRGKNADIIYRIVEELMVFNPPFIDVTSHAADADYIEQ
PDGTFMRKITRKRPGTIGLSAAIKYRFKVETVVHLLCNGFTREETEDALIELNYLGIDNI
FAVRGDVRNYKKIHQPDRTVNNYAKDLVCQIKNMNSGVFLEDEQDADPTDFCIGVGAYPE
KHEEAPSLAADIRYLKQKVDAGADYIVTQMIFNNAKYFKFVDKCREAGITVPIIPGIKLL
TSKFHLTSLPRHFNISFPDKLVQDVQAAKNNTEVKEIGIDYARKQVEELLNSGVPCIHFY
IMQDPASVKQVIKSLGI
>A0A3D3P7F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriaceae bacterium|TrEMBL
MKITDHIANAKGKTLFSFELLPPIKGQSIQGIYDAIDPLMDFNPPFIDVTYHREDYIYKQ
HPTGLLEQILYRKRPGTVAICAAIMSRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADPGFILTPGGHAYATDLLEQVVNMNNGVYLHENHDSTFKTQFCIGVAGY
PEKHFESPNLKTDFSFLKKKVEMGAEFIVTQMFFDNSKYVEFVKQCRENGINVPIIPGLK
PITSSKQLISLPKIFHIDIPEELSEAVTNCKSEKDVKEVGIEFMIRQCKELIKVGAPVLH
FYTMSNPGPTRRIAEAVF
>A0A1T2XS09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKSAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVQALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A8J2ICX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium equiseti|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKSIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFENTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAVYPEWEATGLEAGVRAEAINSRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGNPKTRRDINDLFVKHIQGELSAIPWSE
EELLAESSTIKPHLLELNGKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PSNEWETLRAKLVSSELQDYVCFYASNARGDYVSSDIGGHVNGSTEGNPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNLIHHDY
VNKDALWEVLSS
>C5AZM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1)|TrEMBL
MPNASQHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVDATKEEIDGVVQSYWEAGVRHIVALRGDPAEGVG
HSYRPHPGGYAQTCDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIEALKAKVDAGADQ
AITQFFFDNEIYLRYRDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLENDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
PAVKPEAKAA
>A0A257ADF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermofilum sp. ex4484_15|TrEMBL
MLGCPKGLLNGPCGGVREGGICESGSIKCPWYEAVIREGIRLATPKLDEGFRVRDFKPLL
KDPYSTFLSKLSRGNDVLVAEIVPSLSSLKYVKECGKLADALSITDNPAGTVKLSPLAFV
AMLKGSIESDVIIHLSCRGKDRDTLTSTILGALGLGVRNFLAVTGDLPKSNLSKTFFDLD
STRLIYLARLLSDKGLNYRGGKVKVSSKFHVGATLNPHLRPVKVEVVRALRKVRAGAEFL
ITQPVYEFNPLRELLNNLIKLNIDVPVVMAVALPTHPKALGYLRDMGVKVSKVFFKGFIR
SYKSSREVGALKYCLGETSKLVEEALSSNLLIRGIYITTVGKHSYLPYALKSLRGIVGS
>A0A1C6EVI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MNLDTLLKQKRPVITDGAMGTYFTQKTGFSIHECEWANISRPELISEIHREYVKAGAQFL
RTNTFSANTKSLGRPLADVLEIVRAGYRLAKEAAGCQAVAAADMTAIYPRGDEETDLLPE
YLAIADAFLSEGAEVFLFETLTELSPFDQIADYLKKKKPECKVLISFTVSPEGITRLGVP
LRRLLDEVKPHRELFDGIGLNCGCGPAHILKFARELLSYSRQYLSLPVLVMPNAGYPAME
ENRTVFDTSPEYFSHQAVRIAELGVDMIGGCCGTTPKHLQLLSRLIQKKREPLAAVTTTV
TAVGSLEKSAPRESRFAQKLRKGEFVMAAELDPPYGSRVDKLLTACRVLQNSGVDIVTIS
DSPMARVKLDPVVCGAKLQRETGMEVLPHFCCRDRNVNALRAMLLGAQCENIRTILAVTG
DHVPELDRGYIKPVFNVTSAKLMEMISQMNQDVFADSPFTIGGAFNPNVANSKAELARLE
KKLKAGAVFFLTQPVFDEGRISTVKEAREMGAKMLLGIMPLVSYRNAVYMNNEVPGIQIP
TAYVNRFSPEMSREEAQRTGIEIALEIAESLRPHADGFYFMTPFNRAEIVAELIEKCREM
>I4D601|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus acidiphilus (strain DSM 22704 / JCM 16185 / SJ4)|TrEMBL
MENKFKESLLDKNTLSVTWELVPGRGANEKAQEVAITSAEQAAKGGRVHALTITDNPGGN
PAILADNLGMEILNLGIEPLVHFTCKDKNRNQMESQLYALDRANVRNLLVMTGDYPVSGF
QGRPKPVFDLDPINTLQLISEMNKGLEIQGMKGPIFQKPSDFFAGAAVSPFKAAEAEQMV
QYYKMKKKIAGGAQFLVCQLGYDARKFHEVLQFLKVNNYDIPVVGNIYILPFGAARIMNQ
NQLPGCVVTDKLLAELDAEKGAPDKGVGARMLRAAKMYAIMKGMGFAGVHIGGHNIKYEQ
VEYIIDQGEDLSKNWQDYIREFDYPQPNGFYYFEKDEKTGLNTDRPANRANLPLDAPVNL
GYSMMRNMHALMFTPNKKLFPVMRSFYHAAEGKKKREKRLHALEHIAKVVMLDCKDCGDC
AMLDIAYLCPMSQCPKNQRNGACGGSFNGWCEVYPNEKKCIWVRAYARLKKYGEEANIDV
PPVPPANWDLYQTSSWSNFYLGKDHSAPILGIKRPESKVPQTKK
>A0A080WUG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892)|TrEMBL
MHIKDKLALAEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMPRERVDDALQSAFKAGCTNILALRGDPPREKEA
WEQTEGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFLDWVKKCRQAGIKVPIIPGIMPISTYAAFIRRTNWVKCAVPKGWMEAL
EPVKNDDAAVKQIGKALVSEMCRKLLENGINHLHFYTMNLAQSTTMVLEELNLKPSTETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSVRDLSDIFVRFLEHKLDRLPWSESAITQESEIIKDDLID
LNNRGFLTINSQPAINGAKSSHPIYGWGPRNGYVYQKAYLELLISPALIDEVVRRIESNA
DLTYHCINKDGELKTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSASRKLIQNTMDTWYLVNIGKAPSIPFVYFLTSMLTNCFSE
>D6ZF21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Segniliparus rotundus (strain ATCC BAA-972 / CDC 1076 / CIP 108378 / DSM 44985 / JCM 13578)|TrEMBL
MSTVSLGEKVTASRSILPGTDSLAQSPLAETGDSVVDEWRRIKRTRTPFSVEFYPPRNES
EEAGLWRAARVFERFGAAFATVTYGAGGKTREQTVRLTGELARETTLPIVGHLTIVDHTL
DDLRSIVAGFADQGVRNILALRGDPPGDDPFAEWVKHPDGLEYAEDLVRLIHTLGRFHVG
VASFPRGHYRAVDLEHDTKYLVQKLRAGAEYSITQIFFDVDDYLRLRDRVVAYDAEQGRK
PIIPGVMPITSLKTLRRVVFLSGETIPPALEERLARAAGKGEHEDRKAVRDIGIQLATEM
CERLVREGVDCLHFNTMNFSKATVEVLSNLGYTFKA
>A0A103B579|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. ABCPW 11|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
GGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLESFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAAAATRTICERLAV
>F0M382|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3)|TrEMBL
MSPPSLIDTHPNLSDAAPVALSYELFPPRSPAAAETLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIIGELLDTGVRGILALRGDLPKD
GGEPAAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEEHDVEVLL
AKQRSGADFAITQVFFHTEQYADLLTRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAAELLERMAAADSDLERLHIGVDATVDLANAALDAGAPGIHIYTFNEHQSALEVLDKLA
LPRRSHASLRRHSTAPQLAS
>A0A2Z3I6S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga sp. 17 mud 1-3|TrEMBL
MLPLASRPSRQASCPIKVSFEFFPPKTAEMETTLWSSIERLAPLDPQFVSVTYGAGGSTR
ERTHATVSRLVRETRLNPAAHLTCVAATKEEVDGVVRSYWDAGVRHVVALRGDPVGGLGT
AYEPHREGYQRTCDLVAGIKAIGDFEVSVSAYPEKHPEAASLDEDIDVLKGKVDAGADRA
ITQFFFDNDVYFRYLDRVRARGIDIPIVPGIVPVQNFRQTANFAAKTGASIPAWLAARFE
GLEEDVETRRLIAAAVAAEQVIDLVDRGVHEFHFYTMNRADLVYAICRLLGLRSEAERVA
A
>A0A1W9Q183|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfococcus sp. 4484_242|TrEMBL
MRKTKTPSRLEKVLAAGHLAVTSECGPPRGSDPAVIIKKAEMIKDHVDAINVTDNQTAMT
RLCSLASVIHLKAMGLEPVLQMVVRDRNRIALQSDILGAASFDINNILCLSGDHQKFGDC
PDAQNVYDIDSMQLIRMARHMRDEGKFVGGDDINRPPRMFVGAAANPFADPFEIRVPRLA
KKIEAGAEFIQTQCIYNLDKFELWLKQARERGLHEKAFILAGITPMKSAGMARYMKNRVP
GMDVPDKLIKRMSSVPPKKQPEEGIHICVETIERLKEVEGVSGFHIMAIEWEERVPEIVE
RSGLYPRPKTG
>A0A1V2NY29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. ALI-6-A|TrEMBL
MDSFELICEVEPPTRPDLTKVRHQIGVMSPIADGFLIPDNHIGRATVSSVAVANEVQAMG
ARGIACLNSRDRNLLGLRRDLLTAAAYGVEQFLFVHGDDPSEGGRTSQLTVRTMIDETRA
TSFPGRGPFQVGATARLGKLPRWKAEADFLYVQVSFDLDELLRWRESVDLSIPVYAGVMV
LASAKMAQNLAGLSQLTIPDALVEAVARDRDAGVDAACEQVLRIRDSGAFEGVHLVPVSR
YRQVAARLEREL
>A0A849AND3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flexivirga aerilata|TrEMBL
MTPRPIPQLLAEDGPSFSFEFMPPRTEKAEAMLWNSVRRIEQVNPTFISVTYGAGGSTRD
RTVRITGRIEQETTLTTMAHLTCVGSSVAELRQIVGEYASVGVTNVLALRGDPPGGPAGE
WVAHPEGLDHADKLVSLVRSLGDFTVGVAAFPDKHPESNDLTADADTLVRKAEAGASFAI
TQMVTDVDAYLRLRDLVAARGCDLPIIPGLLPVTAAGQLQRLTELNGQPLAADVVARIDA
VSHDEAAVRREGIAICTEHSERLLREGAPGIHFITMNKSTATLEVFDNLRQNSFV
>A0A8B3SSX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovorax vibrionivorans|TrEMBL
MKVIEHIDKATSPLFSFEIVPPPRGKNISAVTDIVKKLLPFNPSWVDVTAHSAGAYYNEK
SDGSVERKIYKKRPGTVGICGVIQNRFKIDTVTHLLTQGFTKEETEDALIELNYLGIHNV
LALRGDALNYNKKYDLSRKRNFYAKDLVEQISDVNKGVYLDDISNSFPLDFCVGVAGYPE
KHFEAPNLATDIHYLKQKVDAGADYIVTQMFFDNSKYFEFVDKCREAGITVPIVPGIKVI
KRMNQFSNVPRHFYVDFPDEFVAEAHENPDHIIEIGINWARKQTEELLNANVPSVHFYVM
NDCDNVSKVLKGLY
>A0A642EXI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYQDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A4SE12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium phaeovibrioides (strain DSM 265 / 1930)|TrEMBL
MLVKEILNTAHKPVFSFEFFPPKKDADWETLFETITALSPLNPSYVSVTYGAGGSTRTRT
HDLVTRIQKETGLSVVSHLTCIASTSGETGEILENYQSHGINNVLALRGDKPTGTESIAD
AVKDFPHAIDLVRFIKNNHPDIGVGVAGFPEGHPETPNRLQEIEYLKAKVDAGADYIVTQ
LFFDNRDYFDFVDRCRLAGISVPIIPGIMPVTSTKGMTRMSELALGARIPAPLLKKVLGA
ENDAQVASIGIEWATNQVQELIDNQIRGIHFYTLNMATATLEIFQNLHS
>A0A7K0B649|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium faecium|TrEMBL
MKIVDHISNAKGKTLFSFELLPPAKGQGIQSIFKTMDALMEFKPPFIDVTYHREDYMYKK
HESGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDSDFIPTDGGHAFATDLLQQVVDMNQGQYLHEDIAISEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVTKCRENGIHVPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSEAVSACKSNADVRQVGEEWLVQQCKELIDFGAPVLH
FYTMSNPGPTKSIVEKLF
>A0A4Q2SF77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides ganghwensis|TrEMBL
MRERLDSGERSFSFEFFPPKDAAGEEQLWQAITELEPYGPTFVSVTYGAGGTTRDRTVAI
TARIARETSLLPVAHLTCVGHTTDELTAILRDLGAAGVRHVMALRGDPPGGPGSPWTPTD
GGLTYANELVALIRERTDLRIGVAAFPEGHVEATDLDHDARVLKAKYDAGAEFAVTDMVL
RASDYIGLVERAEAVGADLPIIPGIMPILNLRSMERMAELSRRQLPTEVVARLTPYADDP
QALRAEGIEIATELCEALLDAGAPGLHFYTLNRSKATREIFGNLRITV
>A0A2W5TA06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Archangium gephyra|TrEMBL
MKIRTRLNPSKPCFSFEFFPPRTAEGEKQLWDTLEDLRSLEPGFVSVTYGAGGSTRDRTI
DLVGQIKARTGIEAMAHLTCVGHTKEEISAVLDKLAAAKVDNILALRGDPPKGSTTFQKI
EGGFGYANELVQFIRERDLGFSMGVAGNPEGHLESTKEADLQNLKRKVDEGADFIVTQLF
FDNAFYFDFVERARRIGVNVPIIPGIMPITNFEQIQRFVRVCGATVPMRLQLELEKVKDD
PQAVMQLGVAHATLQCSELLSRGVPGIHFYTLNRSPASRMIVSALRARG
>A0A1Z2L8D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albireticuli|TrEMBL
MRELLASGERSYSFEFAAPKSEKGERTLWNAIRRIEAVGPTFVSVTYGAGGSSREGTVRV
TERMATDTTLTPVAHLTAVNHSTAELRNIIGQYADVGIRNMLALRGDPPGDPMGEWVRHP
EGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSDDWETDVRYFVDKCRAGADFAITQMFF
YPEDYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATELCARLMAEEIPGLHFITLNHSTATLEIYENLGLHQRS
>A0A328XGL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas taeanensis|TrEMBL
MSAHEHPLGISFEFFPPNTEAGKEKLLGVRDALAARNPRFFSVTYGAGGSTQARTTQTVK
SVRESGINTAPHLSCIGSDKGELRELLAQYREDDINSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGNHFEIAVAAYPESHPQAPSFERDLENFARKVKAGANLAITQYFFNPDAYF
HFVERARKLGVETPIIPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIKAF
GEEVVTRLCERLLDGGAPGLHFYTLNQAQASLNVLDNLRA
>A0A2W5Z6W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dormibacter sp. RRmetagenome_bin12|TrEMBL
MRIDSLFARGEPLFSFEFFPPRDDEGADRLFATISALRELEPAFVSVTHGAGGSARDDRT
VRFVKRIREETGLLPMAHLTCRDSTVDDLLDEIRQYQAVGIENVLAIRGDPPNGEGAFVA
RAGGLRFGSELVRLLHDKADLCVVAACSPEKHVESHSLEQDVAAAVQKVQAGASLLITQL
FFDNRVYFDFLARARAAGVTVPIVPGIMPITNVDQVYRFTAKIGASIPAPLREALQTRVD
DAAAVLQLGVAWATLQCSELLRGGAPGIHFITLNRSPATRAILTALRIARPWETRSF
>A0A0V1BFA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella spiralis|TrEMBL
MNSSYNLQMKLKSPAYQRAVTDFGVYFEEDSFLSLMASLEAVELKATGHDLNSAAKKSTD
EIYRSLIDRIKENISSGRRFFSLEFFPPHTTEGLINLLKRVDIFANSQPLFVDVTWVMRS
DPASEKVTSSSSLADCILNFCLLDTMLHITSVQYNEKTVLFNLERAKKIGIRNILALRGD
ISDDANVTTTDFQYACQLVRFIRSHYGDYFTICVAGSYLLYVYCLMIFLFARIILQDLLN
LKAKVDAGADFIITQLFFDEMHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSK
IVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRKLLNREHHVVPGLHFYTLNQEKSILE
QIGFWKKAPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYLCRTRDWKQFPHSRWGDVG
NPAFGNLKHYLFSCIDQMDDSCALDMWDKELSTLEHVRDIFCNFIARTPNRHGHSVRRLP
WNENHLDPAADILKNELIYYNSNGILTINCQAAVNGLPSSDPIFGWGEANGYIYQKVDAR
CILISLGYLEFFASSTCTTILLNHVQNFPSINYHAINFDGSFETFNYDEDATVALTWGVF
VGQEIVQPTVANAASFRVWKDEAFDLWQRWAGLYESGSIGRKLLQKIHDDYRLITLIDND
YPQPCSLSALLRAVISDYWGKKLDDG
>A0A179IT56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenibacillus schlegelii|TrEMBL
MDRRSGRRFQGRPDRCAMSDRNPSCAMPEVVVELDPPRAPAFDRYLQAARRLQAAGVTHI
TIADNSLAHARLSNVVAAVLLRQAFGLSPIVHLNSRDRNLLAQQSTVLGLFAAGVRHFLL
ISGDALALGDHPDGKAVYETDSLGLMERFRGLQAGVDFFGRPLEGPLDVCYGGALNLGRT
LGPHLRRLAAKADRGARFFFTQPIFDPADLERLLEARALLGGRGTLYIGIMPLISAASAR
FLAGVPGMNVPSDVVRALEPYTGEAAIEAGLAQAEALIERAFELGWTRFYLITPYLRAST
TARLARFVLARRPATGASPADDVSTGGGTSTRPGASVGVEAAPELGP
>R7K229|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:277|TrEMBL
MKITDVLQSDKITLSMEVFPPKTTTAVEKVNEAVREIAALKPDFMSVTYGAAGGKNSKYT
IQIAQDIKDSYGVNSIAHLTCLSSTRETVENQIGLMRDAGIENILALRGDIPKEADFPLP
DQFHYAAELVREIKRLAPDMCIGGACYPEGHPEASSKAEDILHIKEKVDAGCEFLTTQMF
FDNSIFYNYLYRLREAGILVPIIAGIMPITRKNQVARSIQLSGSCVPARFKSIVDWFGDE
PAKMKQAGIAYATDQIIDLIANGVKHIHVYTMNDPEVAAGIQNNLSEIIG
>A0A370VJI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. M7|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVRPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWETDVRHFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAAGCDTPIIPEIMPIASVRTLERIPSLTNAAF
PDALRERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHPPQA
>A0A8J6SKD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichocoleus sp. FACHB-40|TrEMBL
MPSIQNSMLFKSFRSAAEAGEFLITAEVAPPKGGNPVHMVEMAQTLKGRVHAVNITDGSR
AVLRMCPLAASLILLQHGIEPICQMACRDRNRIGLQSDLMGAHALGIRNILALTGDPVKA
GDHTDAKSVFDLESVRLLGLIKKMNLGFDWNDKPLTDGATDLFAGAAVDPQLASWSGLQS
RFERKLEAGAQYFQSQLICDFDRLEKFMDKIAAGCGKPIMAGIFLLKSAKNAQFINRCVP
GVNIPQDIIDRLAAADDPLQEGMAIAAEQVKLASQLCQGVHMMAVKREDLIPEILDMAGI
APLNQLVSAGTEDERTNNKATADSVAL
>A0A833S7H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora infestans|TrEMBL
MGKIIESIRSAYATRTDDTSARPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGAEQWSPVEGGLSNAVDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIQWITQCKDAGISIPILPGYLPIQNYSSFCK
FTSWCKTRVPEKVLAALDAIKNDDAAVRRYGTQLAVETCQRLLAAGVNSLHFYTMNLAAT
VTQVLEELQLQPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLKRTELWGTPQSEQDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAAIRENLQWLNSNGFLTINSQPRVNGASSSDPLVGWGGDEGIVFQKAYVEFFVA
PEKMEHLVKVMRRDHPHLSFHALNRRGDEHRNTPLHSVTAVTWGVFPGIEIMQPTVVDSD
SFAAWKDEAFELWQTQWASAYPEVSHSREVIQHIYDSYFLVNIVDNDYANDDSDIFSIFT
QIITEAMDKEQLRARVLELEARREKMFDTLASFQSQQEELNGELRAAHSELAGVRGENLQ
LKEKVRQLQAQLALASL
>A0A7W8G097|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chiayiivirga flava|TrEMBL
MLPLSFEFFPPKTDEQRNQLDRTAAKLKSLSPEYVSVTFGAGGSTLSYTPETVGGLRRKH
ALQVAPHLSCVGGSRTEIGALLAQYRASGCRRLVALRGDLPSGMATPGEFRYASDLVGFI
RAEHGDFFHIEVGAYPETHPQAEDALADLRHFKRKVDAGANGAITQYFYNPDAYFRFVDD
ASALGIDIPIVPGIMPISNFTQIRRFSEMCGAEIPRWMARRMQAYGDDVESIRSFAADAV
AQLCERLIAQGVPGLHFYTLNLAKPTALVLERLGVR
>A0A833S1M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora infestans|TrEMBL
MKVIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMAEADIKKALDQAKDAGIQNILALRGDPVRGATS
FDECDRGFSHAVDLVRYIREKYGNHFCIGVAGYPEGHTEFKDKKADIQYLKEKVDAGADF
VITQLFYDVKVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTSFCNTHVPDEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRASESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSNTSTPRKRRAMWGDAPASKEDVRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGALSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
PSMQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEQGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEPSISPATSP
>A0A8F6Y510|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Riemerella anatipestifer RA-YM|TrEMBL
MKVTEHIKKSEGKTLFSFEILPPLKGQNIQCIFDAIDPLIEFNPSFIDVTYHREEYEYVE
VRDGLLEKRVVRKRPGTVGICAAIQNKYKVDAIPHILCGGFNREDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKNGHTYASDLVKQIQDMNKGIYLDTSLEKAAPTNFSVGVAGY
PEKHMEAASFSQDIGHLKKKVEAGADYIVTQMFFDNQKYFDFVDRCRSEGIGVPIIPGLK
PIATKSQLSLIPHRFKVDLPDDLVTAITKANNNNEAKEIGVEWCIEQSKDLMKNGVPILH
YYSMGKSESVRKIAEAIF
>A0A2T4Q090|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus warneri|TrEMBL
MSQFLNKLQNNVLVADGAIGTIFYSEGLDTCPEAYNLTHPEKVERIHRSYIDAGADVIQT
NTYGANFEKLKAFGLEHKVKEIHKAAVQIAKKAANEDTFILGTVGGFRGVKQDDLSLSTI
QYHTEHQIDTLVDEGVDALLFETYYDLEELKGIVVSTKRKHHIPIIAQLTASNTNYLVDG
TPINDALKQLVECGADIVGLNCHHGPHHMQRSFSHIELPDKAFLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIRYIKTSVKNLRPVVHKNVIPINKKV
NRKKDLNSKQSLTSKVKQGPTVIVELDTPKHLDTDQFFNNIGKLDDADIDAVTLADNSLA
TVRVCNIAAASIIKQRFNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEATKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEEVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITTHKEAIL
>A0A7L0ZW93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxyruncus cristatus|TrEMBL
MVNETQQSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGHRVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>L7KWB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia amicalis NBRC 100051 = JCM 11271|TrEMBL
MPFSVEFMPPRDAEGEARLWRAVRIFERLSPAFVSMTYGAGGSTRDRTVRITGELAAQTT
LLPVAHLTAVNHSVAELRALVGAYADQGITNILALRGDPPGDPLGEWIKHPDGVEYAEEL
VRLIGTLGDFHVGVASFPEGHHRAPDLEHDTRNLVNKLRAGAEYSITQMFFDVEDYLRLR
DRVQAADPEQGAKPIIPGIMPVTSLASIKRMAELSGSVIPPNVVERFARAAGDGPEEDRA
AVRAVGIDFATETAERLIAEGAPCLHFCSLNFAKATSEVLARLGVDVDAALHVPA
>A0A4W3HW29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callorhinchus milii|TrEMBL
MMVKQRQHNGQLSKSGESCSDSSSRESSRSSTPSLESDRLREKMRRRIESGDKWFSLEFF
PPRTASGAVNLLSRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETL
LHITCCNQSKEQITEHLQKACRLGLKNVLALRGDPIADKWQTEEGGFNYASDLVKHIRNK
FDDYFDICVAGYPTGHPECTSYEEDLKHLKEKVEAGSDFIITQLFFKPQTFLKFLKDCRA
IGITCPILPGIFPIQGYHSLRQLVKLSKLQVPQEIKDIIEPIKDNDAAIRNCGIDLATDL
CKALLTSGAVPGLHFYTLNREVAATEILRRLGLWIEDPRRPLPWAVSANPKRKVEDVRPI
FWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSNCAKEELLKMWGEEL
VNEEHVFEVFTAYITGESNRNGTKVTCLPWNDESLAVETNLMKAELQKVNRRGILTINSQ
PNINAKSSTDPVVGWGPEGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVKS
ENINNASDLQPNAVTWGIFPGREIIQPTVVDPISFMYWKQCCINLCLLFSAVNWPPHKCP
APHIKCKWLSHCKTCD
>W5WFV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kutzneria albida DSM 43870|TrEMBL
MTSVVERLSGPRPVFSVEFFPPRDAADEQQLWLAIRQLEGLDPAFMSVTYGAGGSSRDRT
IRTTGRVVQETSLLPMAHLTAVDHSVAELRNVIGWYAAVGVRNVLAVRGDPPGDPNGEWV
KHPQGLTYAEELVRLVRDLGDFCVGVSAFPYGHPRSQDLDTDTEYLVRKFRAGADFAIAQ
LFFEAEDFLRLRDRMAAKGCDSPLLPGILPLTTVRTLRKTVELSGAQVPASIARRLDPLQ
DDPVAFRAEGIDIVTELSQRLIDEGVPGVHFYTFNRSKATTEVVGRLGLLPARA
>A0A1V5CVH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdus sp. PtaU1.Bin058|TrEMBL
MKVDSNLKNVLTKDNFAVTAECGPPKGADPGIIQKKGDILKGYTDSVNVTDNQTGVVRLS
SMAACAILRQGGLDPVLQMVTRDRNRIALQSDILGASALGIRNILCLSGDHQSFGNQQQA
KGVFDIDSVQLIQTVRRMRDEGRIIGGEALWQTPSPIPSTTGSPA
>A4BD39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reinekea blandensis MED297|TrEMBL
MNTPVPVSFEFFPPKTDAGYDNLLKAHDELKTTNPEFFSVTYGAGGSTQERTINTVIELN
KRGVPAAPHLSCIGSKADTIKDLLTTYKAEGINRIVALRGDLPSGMVGTGGDFNYASDLV
TFVKQEFGDTFHIEVAAYPEMHPQAANLDADIDNFVRKAKCGADSAITQYFYNANAYKHF
VDEVRKRDCDIDIVPGIMPITNYSNLVRFSDACGADIPRWMRKALETCSDDVQRIQRIGL
NFVVDLCQDLIQAGAPKLHFYSMNRSGPTLDILKQLS
>A0A142LNW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium UKL13-2|TrEMBL
MESTSRQFSFEFFPPKSAEGAVKLRETVTQLGQLNPAFFSVTFGAGGSTQEGTLKTVNDI
RAMGYNAAPHLSCIGSTVESIREIVHRYRDAGIRHMVALRGDLPSGMAMAGEFRHASDLV
AFVRTETGDHFHIEVAAYPEYHPQSRTAQEDLKNFKRKVEAGATSAITQYFYNPDAYFHF
VDEVRAMGIDVPIVPGVMPIGSFSQLARFSDACGAEIPRWIRRKMEGFGDDSASIKAFGL
DVVTDLCQELLEGGAPGLHFYTMNGAGASTTIWQRLGLS
>G4RG07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterium halotolerans (strain DSM 22347 / JCM 15775 / CGMCC 1.7692 / B2)|TrEMBL
MVSATGESRLSRQPESGRPELAVSFEFFPPKTDVMEERFWASLSRLAPLGPRFVSVTYGA
GGSTRERTLRMVSRITNETGVPAAAHLTCVGATRDEVDDVVRGYAEAGVKRIVALRGDPP
EGVGHAFTPHPDGYNSAADLVAGIRKLGDFDISVAAYPEKHPQSVDWDADIDNLKRKFDA
GADRAITQMFFENGDYWRFVERARKAGISAPIVPGIQPIHSFRQIAGFAGRCGASIPQWL
ADRFDGLDDDPETHALVAAAVAAEQVTELLDSGITEFHFYTLNRSNLVLALARLLGIRP
>A0A0P7AWM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceitalea dokdonensis DOKDO 023|TrEMBL
MKVTKHIEKAKGETLFSFEIIPPVKGKNIQELYDNIDPLMEFNPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTLGICASIKHKYNVDAIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMREEKYFKATEGGHPYAASLVKQIQELNCGNYLHEVIETDDCADFCIGVAGYP
EKHMEAPSLQSDLKRLKEKVDLGADYVVTQMFFDNAKYFEFVDAARGAGIQVPIIPGIKP
IAIKKHLQLLPQVFSIDIPQDLVDAVEKCNSNKEVRQVGVEWCIQQSKELKTAGVPVLHY
YSMGKSDNIKKIAKEVF
>H8X3U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida orthopsilosis (strain 90-125)|TrEMBL
MSKVKDLIQSLAPEEKFISFEFFPPKTDSGFRNLLARLNRLSAFNPLFITVTWGAGGSTS
EKSLDLAATCQKKIGATTVLHLTCTNTNKEVIDAALKRAKENGIRNILALRGDPPRTEEY
WTPNCQFKNAVDLVKYIRSEYGDYFCIGVAAYPEGHVDGADISNQNPRKDIPYLVEKVKA
GADFIITQLFFDVDKFIAFERLIKQSPELKDVPLIPGLMPITTHRVFTRATKLSHATIPT
KVYRQFDEIKNDDDAVKAVGVDLLCDIISKIDERTDIKGYHFYTLNLEKAVASILNKSDV
LRPILEQPSPVFGNEDAIASDSDDEEDLPSPHQKRKHRKSSVVEPLTQKAVVEISRGLGA
LGKEAIWDDFPNGRFGDSNSPAYGEIDGYGPNLKIYDKSEAIAKWGSPESIKDLSRIFTS
YLSGKVDVIPWADVPLSPETALIQEELFELNEKGWFSVASQPAVNGCKSTDNIFGWGPAN
GIVYQKSFVELFMPARDWENLRSHLDDSTTYYVGTKSGEIKSNLPIEQDFGKSKSAVTWG
VFPQKEILQPTVIDYESFKAWNEEAFLLWLEWARCYKKSSKSFALLNSIYNDYVLVSLVH
HEYPKEDALWQLLLQ
>A0A2P2HGX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus flavus (strain ATCC MYA-384 / AF70)|TrEMBL
MHIKEKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAAEGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLLPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIKDLSRLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLIE
LNNRGILTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDSWYLVNIVNNDFHNTYDLFELFKDLNVRDFDVEVAADNADLK
SQENETAETTAN
>A0A4R6G2N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. BK668|TrEMBL
MPADQRSTGSVPFSFELYPPRSDAAASELGETIRVLADAGPQFISVTYGAGGSTGGASLD
VLRRIRATGVEPLAHLTCVGNTYEGANRLIREFLDADITSFLALRGDPPAGASEDDAFLG
DLESAAQLVQLIDRVQAERAPYTEASIPGVPGAVRVAGRRRVDIAVAAFPNGHPRSRHPR
EHIDALLAKQAAGATFAITQVFFHADDYLCFVERARRAGVGIPILPGIMPIVSPGRLRRV
LELTGEELPGELAVALEVEPTAEGRRAVGVSAAARLTREVVDGGAPGVHLYAFNSHDAVL
AVLREAGIPTRRSEPTRRSEPTRRSETHHPSELEAAR
>A0A1I3VNB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sacchari|TrEMBL
MTTQQEVPGARRSGFAELVHAMSYEVMPFKNTERDVLEYVPTSVPLTVTVTEAKGIGATL
DLAERLLGHGYQVAPHLPARQFTDDAHVADVVARLRESGFRSVFVVGGDAPKPAGRFTDA
YSLLQAMDELGHPFEEVGIGGYPEGHAKIPQEALDLALKQKAPLATRILTQICFDAGTTA
NWAAGLAEDGIGLPIYVGMPGPVNRQKLVRISAGIGLGQSARFLQKQQSLFWRFLLPGGY
NPTKLAKRLAAAAPKVDANLGGLHIFTFNELRGTEQWRQRLLASLPEKDRS
>W4HPC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivivax marinus|TrEMBL
MTPPDISLEFFPPKSLEASFRLWDTVQKLAPLEPRFVSVTYGAGGTTRELTRDAVKTIHR
HSGLRTAAHLTCVNATREETLDIARGFWDVGVHDIVALRGDPPKGEDRFTPTDGGFANSC
ELIEALKAERDFTVRVGAYPDIHPDAGSMDADVTYLKRKFDAGADEALTQFFFDADAFFR
FRDACVAAGIDKPIVPGIFPVENWKGARRFAEGCGTRIPDDVAARFDAAEADGSSEAFAR
DFCIDLCERLIAGGADKLHFYTLNKPELTQDVCKALGVTRSDRLVA
>A0A4R6G990|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. BK668|TrEMBL
MARTTPAPDRQAARELVRDFSLEMTGKDIPGLEEAKHAIPLGTKINVTFLGNEDLDMRVA
AAKAVKDLGFVPVPHISARRLKSQDQLEEFLGRLQEVGAAEHVFSVGGDPTTPEGPYESS
LDLIRSGILPRYGVREVSVAGYPEGHPDIKTDVLWRHLEDKTAALKEQGLDAVILTQFAF
DTDPVVDWIAEVRRRGIATEIRIGTPGPAGIKRLLGFARRFGIGANAMIVKKYGFSLTNL
MGTAGPDRFVTDLASLLADPSTGAGTGGAGSVKLHFYTFGGLLATSEWARDFSAAQS
>A0A389MAM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacterales bacterium|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASREELIQIAQDYWQSGIRHIVALRGD
LPPGGGKPDLYATDLVHLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPQWMVGQFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPDAAAPI
RAAV
>A0A126RC46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. MI1205|TrEMBL
MTLSFPSIEEDRRAWQAPLYADLAGDIHVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFV
SVTYGAGGSTRERTHNTVARIARETPLAAAAHLTCVAASKAEIDEVVDAYWEAGVRHIVA
LRGDPPEAGTKFQPHPEGYKGAAELVEGLRKRHPFEISVAAYPETHPDALNAQSDIDNLK
RKLDAGASRAITQFFFEPDTFFRFRDTVAAAGINAEIIPGIMPVSNFAAVQRMSAMCNTN
VPGWMGKLFEGLDDLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPATLEKTA
>A0A0G4JSF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brenneria goodwinii|TrEMBL
MSFFHANQRESLNQSLAELQGQINVSFEFFPPRTSEMEETLWNSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCVDASRDQLREIAQDYWQSGIRHIVALRGD
LPEGGGKPEMYAADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSMFE
GLDGDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAVA
>A0A495UDN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. AG1240|TrEMBL
MAHTSPAGDNAASVRLVEGFSLEMTGKDIPGLQEAQSTIPAGTKINVTFLGNEDLEMRVA
ACKAVASMGFVPVPHISARRLSSQAQLEEYLDRLQQVGATQNVFAVGGDPAEPEGPYPDS
LSVIRTGLLQKYGTTEVSIAGYPEGHPDIPNDVLWQHLEDKSAALKEQGLGAVILTQFAF
DTDPVTAWVNGVRERGITSEIRIGTPGPAGIKRLIGFARRFGVGANAMIVKKYGFSLTNL
MGTAGPDKFVTDLAAELAQNPASGDVKLHFYTFGGLKATSEWARDYIAARV
>A0A1M3DD13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. 67-36|TrEMBL
MTLSLNQMEEARRALDAPLYADVAGDIDVSFEFFPPKTEKMEETLWHSIGTLAPLAPRFV
SVTYGAGGSTRERTHATVARIARETAIPAAAHLTCVEATREEIDAVAREYWAAGVRHIVA
LRGDPPVQGARYQAHPGGYENAAALVEGLRRLHPFELSVAAYPESHPDSADAAADLDNLK
RKIDAGATRAVTQFFFEPETFFRFRDRVAAAGIAAEVVPGIMPVSNFAAVQRMSAMCGTA
VPPWMGRLFEGLDDLPDARQLVAATLTAELCRKLYAGGVKQFHFYTLNRAELSFAICHLL
GLRARNGAQAVAA
>A0A5B0WVX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. B2(2019)|TrEMBL
MKPDLRSAWGNKVLVGDGAMGTYLYQKGFPVGISYEELNLTSPGVIEDVHRSYIDAGAVL
LESNTFSANFDRLSKYGLESKVEEINRAGVRIARKAAGDTGYVLGAVGSIRAGKRANLSS
TELKKYFTQQITALLEEEVDGIMLETFYDVEELHLALRTVRKHSTLPVICQFAVDESART
LDGLTLPEAFRILEGDGADIIGFNCNTGPNGIKRALKAVQGNLILPTSVYPNAGVADYVD
GEYRYGASPEYFGQMAVTFAEMGCRIIGGCCGTTPQHIAEISSALKDYVPQPLPEPTLPT
VERVSLQEHFGEDEGRDGREPNLLDLVKERHTVIVELDPPRDLDIGKFMKGAEALRRAGA
DALTLADNSLAVTRMSNMALGHLVHAKTGLRPLVHIACRDRNLIGTQSHLMGFDALGIDH
VLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGISFSGKPLKQKANFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDQQLIVKIAEATAHLDIPVFIGVMPLASGRN
AEFLHNEVPGIQLTDDVRNRMKGLEGEAGRAEGVAIAKELLDVATAHFNGIYLMTPFMFY
DMSAQLIEYVWEKSGRKLSPLFR
>A0A7Y5SHB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pirellulales bacterium|TrEMBL
MIATDSKPSYREMITGDRFYYGVEVVTTRGLSPPGSPGDLAALAGSLLGDPRVGWISVTD
NPGGAPMLPPDWLAGLLPDKRGRIVVHLTCKDLNRNGLEAAAWRYASEGFDNVLALTGDY
PTTGFHGQANPVFDLDSTGLVSLLRSMNDGLKIPGRRGGVEVLPQTNFFIGCAVSPFKLH
EHELVPQYLKLIRKIAAGTQWVIPQLGYDMRKFHEVKLVLASRGLEVPVIGNVYLLSKVV
AKLFHSGKLAGCVVSDGLLEQAEKYGGGADKGRVFFQELAAKQLAVFKGLGFAAGYLGGM
AKPETFSSIIEKAESFAPDDWREFIREIQFSRPGEFFLFDHDPQTGLSEPARVNREFLRS
LERPPKNGEVTLSYRFSRLVHDIAFTENKGLFGLFRRLYSRWEKKPGRLSRFAYWLEKNA
KHLAFECQDCGDCSLPDCAYLCPMIACSKHSRNGPCGGSADGRCELGDKTCFWARVYQRM
KFYRQSETMFDRPIVFYHPELKHTSSWANRYLDKDHQALDRPNGDGVQQDAPA
>A0A4R2M292|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor plautii DSM 6740|TrEMBL
MMDIRTYLSQGKPLLFDGAMGTYFAAHPGRAEERCERANLTRPEEILRIHRAYLQAGCRA
IKTNTFAISGDLSDGNDETACDIVNAACHLARQAAQPYGAYVFADLGPAPRDHSRAPADL
YQTQAQWFLEQGVTHFLVETLSGDEGLPELAGWLKEKNPDAFLMVSFAVDHSGMTSAGRL
GSELYRFASELAGVDAVGFNCVSGPRHLLKYIQTLELSDKPLTVMPNAGYPTVLGRRTVF
GGQPDYFAGQIAQIVQAGASIVGGCCGTTPEHIAQTAQALKEPLPKCTVSAPKKLLKPAA
NASNSLWEKLEAGKRVIAVELDPPVDDDSAGFWEGVQALRGSGADAVTIADCPIGRPRAD
SSLLACKIKRDIGIEPLPHMTCRDRNLNATKALLLGLSMEGVHNVLVVTGDPIPTEDRNE
VKSVFNFNSRKLARFVHMLNENTLRTPFRIYGALNLNARNFDVELRRAQEKEACGVSGFL
TQPVLSAEALDNLKLAHKTLRGKILGGIFPVVSHRNACFLNNEISGMRVCDEIIHLYEGK
DRDAAEALAVTVSTAIAKEIFPYTDGYYLMTPFRRVALMEHIIQNIQQSCIS
>A0A031HWT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. RIT328|TrEMBL
MTISVTQLEEAQIALKAPLYADVAGDIAVSFEFFPPKTEKMEEQLWEAVRTLEPLAPDFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATRAEIDQVAEDYWAAGVRHIVA
LRGDPPAAGAKFASHPGGYENAAALVAGLKRLHPFEISVAAYPECHPDSRDMAADIDNLK
AKFDAGATRAITQFFHEPETFFRYRDKVAAAGIDAEIVPGIMPVTNFASVVKMSKMCGTD
VPAWMARLFEGLEDHPASRQLIAATLAAELSRKLYAGGVKSLHFYTLNRAELAFAICHLL
GVRSKPVASAAAA
>D0LAU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / BCRC 13721 / JCM 3198 / KCTC 3076 / NBRC 16047 / NCTC 10667)|TrEMBL
MPFSVEFFPPRDAEAEGRLWRAVRIFERLSPAFVSMTYGAGGSTRDRTVRITGELAAQTT
LLPVAHLTAVNHSIAELRALVGAYADQGITNILALRGDPPGDPLGEWVAHPEGVEYAEEL
VRLIDTLGDFHVGVASFPEGHHRAPDLDHDTANLVRKLRAGAEYSITQMFFDVEHFLRLR
DRLAAADAEQAAKPLIPGLMPITSLASVRRMVELSGSVLPPTVEERLSTAAGDGPEEDRA
AVRAVGIDLATEMAQRLIAEGVPCLHFCSLNFAKATSEVLERLGVDVRDALGAPVGA
>A0A550J7E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas acetexigens|TrEMBL
MSRLAEQLAAGRFVVTAEIAPPKGIDISPALAKARLMTELAAVNVTDNQGANMRLSPLAL
SALLLREGIEPILQLTCRDRNRLALQSDLLGAAALGIENLLLLSGDHACFGDHPQARSVF
DLDSIQLLAAVRGLCAGHDMADKPLRGVPHFFAGAAVTPEAEPFELMFQKFAKKAQAGTA
FFQTQAVYDVDKLTRFMEAAAPLGKPVLLGVLLLKNARMAEFLNRSIPGVRVPARLIERL
DNAADPLEEGIAIAREMVGHARRLCQGVHLMTLGHEERIGDIIA
>A0A2N1G699|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. ALD4|TrEMBL
MKVTNHIEDAKGETLFSFEIIPPQKGKSIQDLYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGINN
VMALRGDAMKDEQSFVPKIGGNNFAVDLVQQIKLLNEGKYMHDVMHVDNKANFCIGVAGY
PEKHLESPSLLSDLKRLKAKVDAGADYVVTQMFFDNAKYFEFVAKAREMGIMVPIIPGIK
PLAVQRHLQILPQIFRIDLPEDLIQAVEGCKTNADIKEVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKIF
>A0A2J0LJ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG12_big_fil_rev_8_21_14_0_65_50_5|TrEMBL
MFRISDIFSSKAKTVSFELFPPKTDEAYIKLLSTIDQLCTLKPDFISVTYGAGGGSRKKT
QDIVGHIQDKHHIAGLAHLTCVLHTKDEIKAILEQMKSREITNVLALRGDPPQHQPDWTP
GPENFRYSSELAALIRKQFGNYFTIGVAGFPEGHVLCPNRERDADYLKIKIDAGADFVIT
QLFFNNKDYFDYVERLKRRGIRTRIIPGILPITNYQGLTKFCKVCGSTVTDEVKQIFEPI
QNDPKATSKAGVDFCVRQCRELLKGGAPGLHFYTLNKLSPTDQVLKQII
>A8ZTK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfococcus oleovorans (strain DSM 6200 / JCM 39069 / Hxd3)|TrEMBL
MKAGSHLEKILRAGHFAFTGEIGPPRGTDVEEVKEKARFLKGNVDMANITDNQTAVVRMS
SWATSLVVMEEGVEPNYQMVCRDRNRLAMQADILGAYALGIRNILALSGDHQQFGDHPFA
KGVYDLDSIQLVNMIKNMRDEGKFQGGADISHPPKMFIGAAANPFAEPYEWRVHRLAKKI
DAGADFVQTQCIFNMERFREWIRQANDMGLTEKIYILGGITPMKSIGMARYMQKKVPGMD
VPEAIIKRLQGVDKKEVANEGIKIACEQIQELKETKGVAGVHLMAIEWEHKVPEIAEKAG
MLPRPVVEDDPAPEAKKGDAE
>A0A436KT32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.002.04.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A4Y7WPL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus lehensis|TrEMBL
MSRLDLKKLLTSSVTVADGAIGTLLYEAGYDLCFEELNVTKPEEIYAIHQAYIEAGATII
QTNSYAANAQKLKRYGLQESVGAINQASVQLARKAVQDSGKKQVFVLGTVGGIQGFQSEQ
LDHKESMQALVEQVDLLLQAEVDGLLFETFYDFSEIKQLVIESRKRTQLPIIANVSLGDI
GVLKGGIRLSDALTELYEVGADVTGLNCRMGPYHMLRSIEELELPYDIPLACYPNASLPG
YRDGRFVYASNTDYFTSMSERFINEGVHLIGGCCGTTPAHIKAIKEAASGRKPVKRKIRL
QSLKTETIERFHEQRPSIKDLVEEKQTIIVELDPPKKLHIDPFIEGAKAIRDAGADALTL
ADNSLASPRIDNQTLAMLLKEEGIRSLVHLTCRDRNLIGLQSHLMGLDLAELNDLLVITG
DPSKIGDFPGATSVYDVSSTKLLPLIKQMNEGISFSGKSLGRATNFTTAAAFNPNVKHLD
KAVRRLEKKIEAGAHYFLTQPIFDEKQFEEVYEATKHLSVPIFVGIMPLTSSRNAEFLHN
EVPGISLSDDTRVRMARAGEDKVKAEQEGLAMAKSLADAAATYFNGLYLITPFLRYRLTV
ELTRYLRTHTTAPLSKERKLQ
>W9DX32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanolobus tindarius DSM 2278|TrEMBL
MSRTFKDKLSSNDFLITAEVSPPKGTDLAEMISDAELTRGWVDALNVTDNQKAIMRMSPL
AVSKALLDGGHEVIMQLTCRDRNRLALQSDLLGAYSMGIRNICIMTGDHTTKGDHPKARP
VYDLDSVQLLNIVRKMQRGIDLAGNVIENPPQFVVGAVTNTDPSRKAQMMKLRKKVKTGI
DFLQTQAVYDISMFEDFMESIEDIEVPIIAGVIPLRSANMARFMNGNIPGINVPDEIIER
MDSTEKPKEEGMVICAEAIKELQKLSRGIHLMPIGKHNNTPTILEMADIRKKR
>A0A7X8C7I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MNVAELLRQTKETLFSFELLPSLKGDTIQAIYDTIDPLMEFKPSYINVTYHKEEVVYKQR
TDGLLEKRSVRKRPGTVGITAAIMHKYGIEVVPHLICGGFSREETENALIDLHFLGIQNL
LVLRGDPDKNQRLFIPETDGHEHAIGLLKQVIDMNNGIYLDVENNNNARTHFVVGVAGYP
EKHPEAPNIENDLHYLKAKVDAGATYIVTQLFYDNRYFFDFVKRCREIGIQVPIIPGLKP
VSIKNHLNIIPKTFGVDIPEDLSREIQKCKNNDEVRQLGIEWTSAQARELKAAHVPSIHF
YTMGKSDNIKEIVKRVY
>A0A285QD34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. LV10R510-11A|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQVVRDQLAGVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTREEISELLDVYKENGINRIVALRGDTPSGMGASGEMRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKLGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDKESIRK
FGEEVVTNMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGIGEREKIAF
>A0A7C4P0K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVIDILNSTKSTLFSFELLPPLKGHNIETIFTTIDKLMPYNPAYINITYHREEVVYMPN
ENGNQVPVKVRRRPGTIGLAAAIQQKYGIDVVPHIICGGFDTHETEDALIDLDFLGIHNV
LAIRGDADKITGRFEPKTGGHKHAIDLVKQIANLNRGIYLEKLMEKPKPTNFCIGVAGYP
EKHPESPNCESDIHYLKKKVEAGASYIVTQMFFDNKYYFHFVDKCRKAGITVPIIPGLKP
ISIKEHLSILPRVFDVHIPQALVLELEKCKTNNQVAQLGVEWAIEQSRELKSSGVKAIHF
YTMGKADNIAQIAQAVF
>A0A7X7WJJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium|TrEMBL
MEYSFLSRLKQGVIICDGAMGTYLNQKGISYERSFDELNLSKPELINQIHREYIEAGAEI
IETNTFGANSVRLSGYGLEDKVREINIKAARIAREARDIIGKDIYIAGSIGPLGKQLEPY
GKILKAAAKDIFREQVESLLEGGVDLFMVETIANLEEMELIVGIIKKTCDLPIVAQMTFT
AEGMTLLGNRPEDVASHLVPLGVDVIGANCSVGPQMMLEVIQILCEFGTTYVSAQPNAGL
PRLYNGRFVYFSSPDYLAEYARKFVEAGATIIGGCCGTTPDHIAAISKALKDIKPMPEKI
GGYAARDRMNIIAVKDEKKIPTISPFLEKLTHDFVVSVELDPPKGSNPEKLIKVAGELKE
IGADAVNIADSPLARVKMSCLALAYLIKRYVDIDIILHFTTRDRNLMGLQADLLGAHAMG
VKDILALTGDPPSLGDYPQATAVYDVDSIGLVNVIQKLNSGSDFFGNAIGKPTNFSIGVA
FNPTAPDYRLELSRLQQKAAAGGQYVFTQPLFDIDIIKQSVDDIAKYNLPVVLGILPLMS
FKHAEFLHNEVPGITIPNKLLERMKNAGEKSASIGQEIALELIEKSKGYINGLYLMPSFG
KFEVAMNIIKYINH
>A0A7X6YHW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKIPELIEKGGKTAFSFELLPPLKGNSIKQVFKTIDRLIEFDPKYINITTHHSENIYKED
DKGVYRKVNVRKRPGSVAIAAAIKNKYGIRAIPHIISQGFTKEETEYALIDLSFLGVTDL
LLLRGDTKKLDAEQRAMDSHLNATGLQDQVNNFNKGISFDGSRFAPPEVPFSYGMACYPE
KHEESPNMESEIFYTKMKVDNGADYLATQMFFDNRKYFEFVDKCRASGINVPIIPGIKPI
HLMSQLTVLPRIFRTDIPEELEKELRKCKSDNDAKEVGVEWCIKQCKELVEAKVPSIHFY
SLMATESVYRVAKEIY
>A0A8H7VXQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thamnidium elegans|TrEMBL
MKVIDKIRKAEQEGRPFWSFEYFPPKTPQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
DLTTEIVATAQSVYGLETMMHLTCTNMPIKQIDDALEAAKNCGCQNILALRGDPPKGQEN
WESCEGGFSYAEDLVRYIRQKYDDYFCIAVAGHPEGHIDNPDKEDDLLQLKKKVDAGADL
IVTQLFFDIDAFLDFYKKARAIGITVPILPGVFPIQNYTGLKRVISFNNNVVPQSIWDDL
ESIKDDDTAVKEYGINLTVDFIKKFREVGVNGFHIYTFNLERSSRIVLERLNLMAPVESV
KPLPWNPSLTSKRAKENVRPIFWKNRAKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
INLKYPVEQCLEMWGTPTCIDDIAQTFARYCKGQISGIPWSAQQLDAETDIIRQRLAAIN
LLGYFSINSQPAVNGAKSSHSIYGWGPKNGYVFQKAYLEFFVSPEKLNELIEKISKDPQV
TYYAVNKQGDLRTNTQSDEPNAVTWGVFPGKEIVQPTIVEAVAFLAWKDEAFELWSKWAR
IYDRESKPAELILDITKNWYLINIVHNDFQDENGIWRLFDLEIDGEISRKLLNHSVAR
>A0A7J6TH58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perkinsus olseni|TrEMBL
MARLIDKIQDRWDHDRDNGESTRVPFFSFEYFPPKTDMGVQNLYERLDRMAELGPMWIDV
TWGAGGSTSGKTFEICRNALTYHGLDVMMHPTCTDQPVKEIDEVLQKCKEVGIRNILALR
GDAPMYSSEWKACQGGFSHAVDLVR
>A0A3E0J3H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacillus trueperi|TrEMBL
MDLREALQNRTLIGDGAMGTLLYSYGIDRCFEELNLSHSEEVLNVHRAYVNAGADVIQTN
TYGANYIKLERYGLQDQVKEINTAAVKLAKQAAGENQYVVGTIGGVRGARKQAISTEEIK
RSFREQLYCLLFEQVDGLLLETFYDLEELTTVLKIARKETELPIIAQVSMHEAGVLQDGT
PLPDALKQLEGLGADVVGVNCRLGPYHTIQSLEEVPLPEKAVLSAYPNASLPAYQDGRLV
YPTDPAYFQKSAQSLYEQGARLIGGCCGTTPEHIEAIAARVKGRSPIQDKVVPIKEKAEV
RVSETKDDRPHLHEKAKKGRSIIVELDPPKKLKTERFLEGAKALHEAGVDSVTLADNSLA
SPRISNTAMASIIKQQYGVDPLVHIACRDRNLLGLQSHLMGLHALGIRQLLAVTGDPTKI
GDFPGATSVYDLNSFDLIHYIKQMNKGISFSGKNLGESTSFSVAAAFNPNVRNLNRAVGR
LEKKIKYGADYFISQPVFNEKQIIEVYEATKHIDAPIYIGIMPLTSARNAEFLHNEVPGI
TLAPEVLEKMELAGSDKEQAQAEGISISKSLIDTALDLFNGIYLITPFLRYEMTVELTNY
IKQQTAERERKMANGIHIV
>A0A0D0NJD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenxinia marina DSM 24838|TrEMBL
MTRPALSFEFFPPKNIEGSFRLWTCVQTLAPLAPEFVSVTYGAGGTTRELTHDAVTAIRR
TTGLNVAAHLTCVDATKDETLAIANNYAEAGVTEIVALRGDPPKGSGGFAAHLEGFSGSV
ELIEALAATGRFTLRVGAYPEKHPEAADLKADVEHLKRKIDAGASAAITQFFFQADTFLR
FRDACDAAGIRAPILPGILPVENWSGARRFAAACGTSIPPLIAEGFDRAEAQGAADLYAT
AVATQLCDNLLTEGVEHLHFYTLNRPELTRDICHALGIVPKVELQRVA
>A0A257QK56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium 21-58-4|TrEMBL
MSSASSISLEFFPPRDIAAQEKLVRSAKQLLALHPSYVSVTFGAGGSTRSGTAATVSLMQ
NLGCEAAPHLSCIGSSRAVLTEILDAYHAAGIRRIVALRGDTPSGMGADAGELRYASELV
RFIREHSGDWFHIEVAAYPEMHPQALTAPEDLDHFATKVKAGANSAITQYFFNADAYFDF
VNRAQAKGISIPIVPGIMPITNHSQLVRFSTMCGAEIPRWIRLRLAEFGDDRASIRAFGV
DVITHLCQRLLDQGAPGLHFYTLNNADSVLAIHRGLS
>A0A1V2UWW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter genomosp. 33YU|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKTQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A2E8Q3J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium|TrEMBL
FLIGFTPLKSVKMIHFMNKYILTKPIPKPVSIRIEKSNNQALEGIKIVVELIKKIRDLTD
KINGIHIMPLGLENHLPDILMKL
>A0A139SJN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cephaloticoccus primus|TrEMBL
MLPDPAISRLFGERPRPLRSLEFFPPKDESGVAALRKTAVALRAFRPDFVSVTYGAGGGT
RQRTAEVSQMLRCELGCVVMPHLTCVGHSRAELYELADAIHASGLRNIMTLRGDLPRGPA
QDGAAASPTPPPADSPRYASDLVALLKARHSDFCLGVAAYPEKHPQAASAQSDIDALKAK
VDAGADFAVTQLFFDNSLYFRFVEKCRAAGITVPIVPGILPALSLAQVRRFTAMCEVVLP
DALASQLDAAGTDNPDAVAELGTQWALRQVEELLAGGAPGYHLYTLNQAQSALAFGACGF
>A0A352F9Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVTDHISNRDRTRVSFEILPPTKGSSIKTIYDTLDPLMEFKPPYINITYHQAEIDLKLR
PDGLLEPKVVRKRPGTVAISAAILSRYQVDVVPHLICGGFSKEETEDALIDLHYLGISNI
LVVRGDANPLSGRFIAEKNGHENAIDLLRQTVDLNHGKYLEEDLVNPEPTDFCVGVAGYP
EKHMEAPNAESDLCFLKAKVDAGAEYIVTQMFFDNRKFFAFVDSCRAAGINVPIIPGIKP
VSIKKHLNLLPQTFKVDIPPALAREMDKCTTNEAVRQVGVEWCIQQAKELIQNDVPIIHF
FTMGRADNILKIARAIL
>A0A3C1PNE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKISDLLNYDKPSFSLEVLPPAKGQDIKVIFENIDPIAKYNPAFISITYHRDEVVYKHLR
TGAIEERTVRKRPGTVAVAAALNYRYGIPVV
>V4RUD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibaculum baratangense AMV1|TrEMBL
MNASIEATPKQVLDTAELAALFPRGTRVYLTDVGTTPLPDFVSAASRLQELGYIPVPHVA
ARRLPSAAALANRMARLKGEAGVDEALVVGGGVDRPEGPFASSMDVLRTGILEAQGYRRI
AVAGHPEGSPDISDEAIADALFWKQEWAADRGIEMRIVTQFGFDAQRYIRWAEDLRREGV
TLPIHVGVSGPAKITTLVKYAAMCGVGASLDFLKKRASSLVTLATSYSPEGLVEPLEREA
AANEQFLVKQFHVFPFGGLKKTSDWLHARGTWTSEAQPASAAF
>A0A836TBH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sneathiellales bacterium|TrEMBL
FLRFRDRAASAGITIPITPGIMPVTNYAQVLKFSKTCGVSVPQDFAEAFEGLDDQPDIRK
LVSADIAIQQCTALMAEGVSAFHFYTLNRVSLTYAICHMLGLRPNPDIIAPQKEGGTS
>A0A2W1L4H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sambharensis|TrEMBL
MKKDLRQALQTSLLTGDGAMGTYLYQLGFPVGVSYEEFNLIKPDVIESVHRRYYEAGARV
IETNTFSANAENLSRYGLEHEVERLNREGVRIARQAVGSDAFVVGAVGPVGAGKRKSIGA
AQMKQAFEQQIGILLDSGVDGLILETFYDLEELLTALRIVRAGSETPVICQLAVEDSGRT
REGTSLQEAFRRLQEEGADAVGFNCVSGPNGIMRAIDMAGLPAGMPLTVFPNAGIPDYVD
GTYMYTAGPEYFAESARHFADRGARLIGGCCGTTPEHVAAIAQAFANYTPDVSRPASAVP
EQDVLAVQAPAAHRAATQPSGTAGGTDAPAPTIVDLVRQRHTVIVELDPPRDLDIRKFMD
GAAALAEAKADAVTMADNSLAVTRMSNIALAALVQERAGIRPLVHIACRDRNLIGTQSHM
MGLDALGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEMIRMIKQLNEGTAFSGKPLKQKA
NFVVGAAFNPNVKYLDKAVQRLEKKIESGADYIMTQPVYDKALIARVAEATRHLSVPLFI
GIMPLASGRNAEYLHNEVPGIQLSDEVRRRMAGLEGEAGRAEGVKIAQELLDEAIAHFNG
IYLITPFMFYEMTAELTRYVWDKTAARV
>A0A3B7PU24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WCHAc010034|TrEMBL
MPQFSDCLQQRKFCVLLEYLTTAKNAAPARASFASWPAFMTLADRVQADDDPAPLAAAAA
YPEAADQLLHYSGKGRDIADFEQFLAQAKARGLRSLLLLTGDKLKQHNDGRLQPELRSRY
LESVNMVMAARRDPDFNIGVAFNPFKYAEAEHDAQYFKLQKKLKAGADYMITQLGFDLDA
LKQAQDFLAQGHYHQPILACVMPLTLARAQFMHRQKVAGIVLTPHLLQLLEREQRQDPLQ
AERNAYLRAALQILICRHWGFAGVHVSACHKASEQRKLEDALQQLQALSLEECLQRWHAL
WQLRTGQELQPEVAVFSRRAPVAQVLKYKNLHAMHELFFSSRAAKGIGGLIFNAPLWNKP
GAEDALLKTEFISKHGALGCESCGQCRIGETLYICPETCPKGLANGPCGGSSLDRCEFGD
RECIHSVKARLAKSVAQTEILKAELIPTVAIETRSTSSWKNWFKAP
>A0A2U3D9W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidibacillus sulfuroxidans|TrEMBL
MGTGKQSLRDFIKDHLVIGDGAMATQLYRLGVPVGVCYEELSVLKPEVVATVHRSYVEAG
AQLIETNTFGAHRAGLERYGLEGQLKEINRAAVRLARAAAKDDAFVVGTIGSVTGARRTL
APPIDLQRAYAEQASALLEEDPDAILLETFLDFRELQTALRVVRNLTDKPIMAQLALLDL
HVTRDGVAVEEAFRRLYAQGADVIGLNCRFGPADMQRVLQAITVPEHAALSVYPNAGLLS
MTDGEYAYPSEPEYFAAAAVQFRALGVRIIGGCCGTTPDHVRAMAQAVGQLSPLAPAAKK
VLTEKRIQQVEPIVTAEVTRSQPVQTIFRNDGAHVGIEPVSEKVRREYTVIVELDPPKDL
FAEKFLVGAQALRDAGADAVTLADNSLAMTRMSNMALGALMKQRGVEPLLHISCRDRNLI
GQQSHLMGLHALGISQILVVTGDPSRFGDLPGATSVFDVSSFDMIRMVKQLNQGIAFSGK
TLEETATFVVGAAFNPHVRHFDKAIKRLERKVEAGADFIMTQPIFDPDFFAVLYDATKHL
AVPIFVGVMPLLSQRNAEFLHNEVPGISLSQEARRRMSLFQGARAREEGVAIARELIDAA
MEHFHGIYLITPLLRYEMTADLTRYVKEKAKMMHNDH
>A0A8C6V031|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neogobius melanostomus|TrEMBL
MVNQVQRGDGTLSSRSDSSAASASGGDSSKESSRCSTPVLDADRTDRLRYKMRRRMESGD
HWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPSGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQSKDNISRHLSKAKHLGLKNIMALRGDPVGSDWEEEEEGFNYAVD
LVKHIRSEFDDYFDICVAGYPTGHPEAHSYKEDLIYLKEKVAAGADFVITQLFFRAETFL
KFEEDCRPSGSPCVCVQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIHQAL
EMCRVLLDSGRVPGLHFYTLNREVATMEVLRQLGMWQEDPRRPMPWAVSAHPKRKVEDVR
PIFWGSRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLVFEVF
TCYIAAQPNRKGHKVMCLPWNDEPLAPETNMLKDELEKVNTRGVLTINSQPNINGKPSTD
PIVGWGPPGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQ
PNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDN
YFLVNLVDNDFPLDSCLWQVIEDMFELLQTGLDTGDEQATIFPY
>A0A6P1VP17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma endbachense|TrEMBL
MTKITDHIKASNGKPIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFTREETEDFLIDLHYLGID
NALVLRGDPAKPFSTFKAKENGYTYASELVEQVANMNRGIYLHEEDTPLAPSNFCIGVAA
YPEKHFEAANHDIDFHYLKYKIDKGADYIVTQMFFDNKKYFDFVERCRQEGITVPIIPGL
KPISTRKQIQILPKIFHLHLPDDLVKAIEACENDQQARQVGIEWSIQQCRELIAHEAPVL
HFYTMGKADNIMKIAREVF
>A0A7C8MVY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylaria multiplex|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTGMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
STKSLELAEICQRELNLTTCLHLTCTNMSRKMIDNALEDAKALGIRNILALRGDPPRAAE
YQDANEDPENAIDEGFVWAIDLVKYIRNKYGDYFCIGVAAYPEGHADESHPLGQSLEHDL
PYLVEKTLAGADFLMTQLFFDTDAYENFERVLREHPSGAFKSIPIIPGLMPIQSYQMIKR
TTKLSHARIPNGIMARLDAVKKDDEKVKSVGVDILCEIVERIKEVQGRTQGPKGFHFYTL
NLEKAVSFIVERARLIASTPEEEAVVDDGPLPSIPDLVINGTSSRELHVHEISQSRRQSA
VGSEPRNRVIVSERTLSNPEYEASQADVGIKAGPINTRANTLAISEGEGVLGREATWDDY
PNGRWGDARSPAYGEIDGYGPTLHVTRAQAISLWGHPKSLEDVNTLFVRHLKGELSAIPW
SEEEVHEETGTITDQLIQLNQRGLWTVASQPAVNGFRSEDPTFGWGPPHGFIFQKAFVEF
FIPAAAWRTLREKLTSPEVRDVVTYYAANAAGDFVSSDLSGTPSPLAVAEATDASDNDYS
AGESSTNAVTWGVFPGKEILTPTIIEEVSFRAWSEEAFGIFSEWAQVYGKGHESEKLLEA
ARADSWIVNIIHHDYMDKEALWNLLLK
>A0A3G7X6J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas orientalis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIQRIVALRGDLPSGMGMASGELRYANDL
VNFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A4R9F3L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MZ04|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKETEQIVADSTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLADWVKHPEGLTYAAELVQLIKESGDFCVGVAAFPAMHPRSEDWDTDVRHFVD
KCRAGADYAITQMFFYPEEYLRLRDRVEAAGCSTPIIPEIMPVTNVRMLERLPQLSNASF
PPALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHHQA
>A0A1H5P8G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ag109_O5-10|TrEMBL
MLADGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVRETQQ
IVADTTLTPVAHLTAVDHSLAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVAHPQGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDTDVRHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVAAAGCATPVIPEILPVTSVKMLERLPKLSNAAFPDALKERILTAKDDPAAV
RSIGIEHATEFCARLLAEGVPGLHFITLNSSTATLEIYENLGLHHPPQA
>A0A4Y8BQU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. US50a|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSVNSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELRA
>A0A2I2F0Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus candidus|TrEMBL
MHIKDKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMGIEKVDAALQAAYKTGCTNILALRGDPPREQEH
WEAVDGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNSDVDQLIDHLKEKVDAGSSF
VVTQMFYDTDNFISWVKKCREKGIHVPIIPGIMPIQTYAAFLRRANWTKIHIPPSWLEAL
EPVKNDDAAVREIGKTLIADMCRKLMASGINHLHFYTMNLAQSTQQVLGELNLLPSEETP
LQRPLPWRPSLGLNRRGEDVRPIFWRNRNSSYVARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSIRDLSHLFTRYLDGKLDRLPWCDTPITSEASEIGGELLE
LNKRGLLTINSQPAVNGARSSHSVYGWGPKNGFVYQKAYLELLVPPYLLDELIARIEKNE
DLTYHAVSKSGELRTNTRDTPNALTWGIFAGREIVQPTVVETVSFLAWKDEAYRLGEDWA
KCHDAASPSRKLIQGVVDTWYLVNIVNNDFHNTYNLFELFKDLDVKDLDVEVATEQKAQP
TVAVNEVSPEVPTKN
>A0A0K8RT43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crotalus horridus|TrEMBL
MVNESHGELSPVSNGLGGTRLDGGSSSSSSGESSQNSSRCSTPVLDTERHERLREKMRRR
QESGDKWFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMM
ATTALNYCGLETILHMTCCNQSRGTITAHLQKAKRLGLKNIMALRGDPFGEEWEEELEGF
NHAVDLVKHIRQEFDDYFDLCVAGYPGGHPEAESYEEDLKHLKEKVSAGADFVITQLFFR
TDTFLKFLRDCQDIGISCPVVPGIFPIQGYHSLRQLVKLSKLVVPQEIKDVIEPIKDNDA
AIRNYGIELAVKMCRELLDSGLVHGLHFYTLNREVATLEILRRLGLWKEDPRRPLPWAIS
AHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKS
PREELLKMWGEELSSEESVYEVFRCYIAGEPNRNGHKVTCLPWNDDPLAAETNLMKDELV
KVNRRGILTINSQPSINGKPSTDPIVGWGPEGGYVFQKAYLEFFTSAENIKALLTVLKKY
GQRVNYHIVNVKGENVTNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWI
EQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPIESCLWQVLEDTYKQLNSPGEEQKT
SGF
>A0A519VFC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKITDHIKNANGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADTSFVPTKGGHCYATDLIEHIKNHNEGKFLHEDIDTFKSDFCIGVAGYP
EKHFEAPNLNADFKFLKKKVDMGAEFIVTQMFFDNQKYFDFVNKCRENGINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPEELTDALSHAKSNAEAKEIGTEAMIKQCKELIEFGAPVLHF
YTMGRPEQTKQIARAIF
>W6TCA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus fabifermentans T30PCM01|TrEMBL
MDLRTALKQRVLVADGAMGTLLYGNYGIASAFENLNLTHPDTILRVHQSYINAGADVIQT
NTYAANRLKLARYDLQDQVTAINTAAVHLAVKARQAADHPVYILGTIGGLAGDTDQDIQR
ATPAEITASLTEQLTALLATGQLDGILLETYYDLPELLAALKVVKAHTTLPVITNVSMLA
PGVLRDGTTFADAIIQLAAAGADVVGTNCRLGPYYLAQSFENLAIPATVKLAVYPNSGLP
GTDQDGQVVYDGEPSYFEEYAERFRQLGLNLIGGCCGTTPLHTAALVRGLASRSVVPHVS
HGYHPAAPSLAPANGQHLFLQKVATQKTALVELDPPKDFATDKFFKGAQRLKAAGVDGIT
LSDNSLATVRIANATIAAQLKLSYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAV
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKQATDFRVAGAFNPNAYR
TTVSTKSIERKISYGCDYLITQPVFDLANVQALATALADNHLDIPVFVGVMPLVSKRNAE
FLHHEVHGIRLPRSVRDRMAQAELDGNERAVGIQIAKELIDGICEHFNGVHLVTPFNRFK
TIIELVNYVQQKNLTPTK
>A0A7W2IBR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. LX20W|TrEMBL
MDNPNFSIEFFPPKTAEGAEKLRATRAKLSELHPKYFSVTFGAGGTTQRGTLDTVLEIMA
AGEQAAPHLSCVGGTRESIRAILAEFKSHNIRRIVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPETHPQARSPQDDLLAFERKVKAGANAAITQYFYNADAYFQFMD
ECGKLGITVPVVPGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTALGQRLLAGGAPGLHFYSMNQAAPTTALWQRLV
>W1W5A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. DORA_6_22|TrEMBL
MSHLLNQLKSNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKSFGLEHKVKEIHQAAVQIAKRAANEDTIILGTVGGFRGVRQEDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELTRIVTATRQKYDIPIIAQLTASNTNYLVDG
TEINAALKYVVECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDIAQELINEGVRLIGGCCGTTPEHIRYIKSAVKHLKPVKDKKVIPINKAS
SQKQTRVLKQNLTSKVKNGPTVIVELDTPKHLDTDTFFDNVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQHYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGINTDGDALKKHTNFNIAGAFDPNVRKLDGAIKR
LEKKVASGMSYFITQPVYSKEKIIQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSDDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A8I2G6N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
VMQMTCRDRNRIGMQADLLGAAALGIKNCLCLAGDHQIFSGAGRLKGHPGAKNVYDVDTC
QLVGIL
>B4MKM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila willistoni|TrEMBL
MFPPVNSSSGYEPCVKFAPSQLSSSERRTNDIGLGSLIENLTARQEFFYGIEISALTANQ
PTCLDFNEFLPTLPAFVSLVWLGISYWNIPMDENYSLQLAKHMESHIPVLAHLSAYRMTE
ERLNEFLAKNFRNVLIVRGDEIHEGQKFTYGREMIEYARQQRKDNLSIGVPGYPEGYHKN
PINDPILNIQYLKEKISAGGEFIITQTCYSSQKIIQFINDCREANVTVPIIIGIMVPDSV
RNYHIVKNITGARLPNEVNDLSVNADDILKFFVDLTVRNIRDIFTANLGIQGIQFFTMNR
FRPVQMVLDELRTLKILQ
>N2ANL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schaedlerella arabinosiphila|TrEMBL
MKIIDRLNEDRIHISFEVFPPKTDAGFDKVMDATDRIAKLNPSYISVTYGAGGGTSKNTA
RIASHIKDDLGVLSLAHLTCASSTKEEVRGVIDNLRQLGIENILALRGDIPEGMAFPTED
RFHYAWELVEEIRKHGDFCIGAACYPEGHVENDHKADDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAVQMKRSQELSGTVFPRRFLALLDRFGSYPE
AMMQAGIAYATDQIIDLLSNGVKNIHIYSMNKPDVAARIMQNLSEIIKC
>A0A7J9X3J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangiales bacterium|TrEMBL
MRNGVLVPRTSATVPTTTRTGIAGLLATPRYEIIPAAAAEAAVVANVPTDVRISITASPT
KGLEPTVDVATRLARAGYQAVPHLSARLIADDVHLAELIVRLRTAGVTEVFVPAGDADPP
AGEFVGALDVLTRLTAMGSPFEEVGITGYPESHPMIADDVTVQAMWDKRAHATYIVSNLC
FDPAVLARWVARVRARGINLPIQVGVTGPVERAKLLAMATKIGVGESTRFLGKHPGMFKR
FAGPNGFSPERYLQRVVDALDRQGTPPAGLHIYTFNQVAGTERWRRRMLGSADR
>A0A7Z3CIE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SK|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSAERFAAMEAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFFTLQLGF
DADKHQEAMHWMSRQATPRPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDLLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGIHELKQLLALEARLEHWQAQIETLEHWAPA
WHASWQMPGLPAVSFHPPQAGWRQGESRVAASFAEKAHYHLMHGMHALLFSRRNALSKAF
GWAVRQPLWATRLGAQVLHTVERAVKQPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLSERLIPCIEVETRHRSSWPQWFQAQTP
RQLSPQPTPRTQPES
>A0A2M7C144|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium CG03_land_8_20_14_0_80_55_15|TrEMBL
MNQSPISFEFFPPQTAEGVEKLTVVRARLATLKPEFFSVTFGAGGSTQERTVDTIRQIHA
EGYQAAPHLSCVGSTRDNIRAMLLAYRQMGI
>A0A1F6REF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Melainabacteria bacterium RIFCSPHIGHO2_02_FULL_34_12|TrEMBL
MTLSQALSNGKFIITCELAPPKGTDVSNLMKMASSLKNQVDAVNLTDGQGGNMRMSPLAA
AVFLLKENLDVIWQVTCRDRNRIALQADCLGASAIGIRNVLPMRGDDPKSGDHPDAKPVF
DLETTELIKVLKQLNEGFDMVGNPLKGKTNLLFGCTAHPNAPDLKKQKETLEERFKLGAG
FIQTQICYETEQIKKFIESLGELAKKTILGITPLKSLKMANFMNEKVFGVSVPKNIMERI
EKAGEQRAEGLLVAKEIVNEIKKTNIGGIHVMAVGQENALPEIIKFLTDT
>A0A5R9IBT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassotalea litorea|TrEMBL
MNYRSARQLDSLNRTVSELTGELQVSFEFFPPNSPEMETTLWNSIERLAPLKPNFVSVTY
GAGSGTRDRTHDVIKRIQKDTGLIAAPHLTCIDANREELVQIAKDYWQSGVRNIVALRGD
LPDSDKKPEMYASDLVSLLKDVEDFDISVAAYPETHPEAPNAQFDLLNLKRKVEAGANRA
ITQFFFDIDSYLRYRDRCVSVGIDVEIVPGILPVSNFNTLKRFAGLTNVNVPNWMYSMYE
GLEDDPATRNLVGASIAMDMVKILRSEGVDHFHFYTLNRSELTYAICHTLGIRP
>A0A2M6ZNS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG07_land_8_20_14_0_80_60_11|TrEMBL
MTAEYSAGSKLEKIFKSGQKAITGECGPPRGADAEFFRHKASFLKPVVDAVNITDNQTAV
VRFCSMAGAKILLEMGIEPVMQMVTRDMNRIALQSNILGAAAMGIKNLLCLTGDHQTFGD
HPQAKNVHDLDSVMLAHTVKNMRDEGKMISGTEVAGRPKIFIGAAANPFADPQEFRVVRM
GKKIAAGVQFIQTQCIYNMERFRQFMEMANDMGLTEKCYIMAGITPLKSVGMANYMKKFV
PGLDVPDSYITRLKGVPKDKVAAEGIKIAVEQIHECLAMKGVAGIHLMAIEWEDHVPEIV
ETAGLLPRPKVEAD
>E9FGM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. C300|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDSGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A259AX63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 24-66-13|TrEMBL
MQFDAERREDPRHEVAPAARSDAKALAMLVERLSIEVSPKEVLHSGHALGVPAGTRTFIT
RLPRGSLEDTRAAAVALRQAGLQPVPHVAVRTVPDAGTLERWLRFFVRDAGVEEILLIAG
SQERPLGAFGETADTLASGVIEGSGLRAVSFAGHPEGHPVADADELQRAIDVKNEFAART
GLSCALVTQFFFDATPVIAWERRLRERGNRLPIDPGLHGVTGVPSLLKHALACGIGASVK
ALSAHGSGGILQFAQIRTPDALAQALAAALANDPDSLFRGFHLFPLGGLAKTVDWMAQVQ
RSAAGTSLAEGVPGAGAEDGIARPPQ
>A0A8I1Z6J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium violaceum|TrEMBL
MTQTPRTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGQAAAPHLSCIGSTRENIAAILNEYRGNGIRHLVALRGDIPSGMVAAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLANFVRKVRAGADSAMTQYFFNADSYFRF
VDEVRARGVDIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRLRMQSYYDDTASIRALGL
DVVTELCDRLLLGGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A061N884|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomicrobium sp. JCM 19055|TrEMBL
MLYSRDITGSIEQANLYAPELVYEAHLEYVQAGADIIQSNTYAANRIKLDTYGLDLQVAK
INKEGMKLAKKAAALKPNVYVAATIGGIKDGRTSDWTDDQIDETVTEQIVALLSENPDVV
LLETYYDLYELIRAVRIVRNHHHSIPIIANVSVRDIGVLHGGITLTEALKRLKKEGANVV
GVNCRMGPAQTITSLKETEIPEGLFLSAYPNASLPGIRDGRLVYQSNPNYFKAQASSFRE
LGINIIGGCCGTTPEHIRGLKERLKGLAPLEKRTVVIEEATDEQVEANESNQQVYDANVI
VELDPPKSLSKMPVFLKGAEALVNAGADSITLADNSLATSRVDNVAAATLIQQKTQASPL
VHIACRDRNLIGMQSHLLGLHTLGVKEVLAITGDPTKVGDFPGASSVYDLTSFDLIAMLK
GMNEATPIRGVPLGVKTSFTVGAAFNPNVSNLEKAIKRLEKKIAAGADFIMTQPMYDKEQ
IKRLRDYTKHLSIPIFIGVMPLVNERNAEFLHNEVPGISLSDTVRSRMQKTLGDSQKGEE
EGLRIAEELQQTCIELFGKVYIVTPFLKYHMSTALVEHARSLIKTSSVMT
>A0A838A8H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloechinothrix aidingensis|TrEMBL
MARTDSRPRRRRAVAGLLEQPRYEVMPLSNVFDEVECLPRGAVVTVTSSPHKGADATIDL
AVRLAEHGVRPVPHLAARQVRDRAELAGFLHRLEAAGIDNVFVVGGDAREPAGEFDDGLA
LLEAMDSIGHPFDHIGIPSYPDGHHAIDDDRLWAALQAKQRYATYTVTQMCFDAATISRF
TLALRRHGITLPIYAGIPGVVDMAKLLRVSLRIGVGDSLRFARGNKAASRRLLTPRGYRP
DALVRKLGAHVQDGKAELAGLHIYTFNHVDATVRWMQTARRKVAS
>A0A7C5U3X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium nodosum|TrEMBL
MEELGKNVFFDNRLILETLPPRGTNAEKYIDFCMNACDVGAQVIAVTDLPMGSARVSPIA
PAHMLTEKGIEVLMHFSRTTRNAIRIEGDLIATHMLGIRNLLILSGDDPRVGTYPFSSSV
EDFSIYDVFRLTKLLNEKGEDIAGVKIYGKFSFNSGGVFSPYEKDYKQTTERMRLKIDNG
CAFFVSQPVFNEEVILKFLEADEELYKSTKIYVAIMVFESIQQLEYFSKVPGVFVPKEYF
RQKTDKGIRNYSLKRAITVIENLLPYVHGFYLTSTTKDLEIIKTVAEVF
>A0A4V3JX76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira ilyithenensis|TrEMBL
MHISQVLERKKTSISFEFFPPKNEEAASDLFQTIQDLSSLNPAYVSVTYGAGGSTRDLTH
DLVVKLQQQTGLIIVSHLTCVGATKDEIGQILKRYETSGIHNIMALRGDPPKGQTEFQKM
ENGFEYAGELVAYIKSNFPKMGIGIAGFPEGHPATPNRLKEIEFLKWKVDQGADYICTQL
FFDNNDFYDFVERCEIAGIKVPIIAGVMPVNSRKGMARMAELALGSRFPAKLLKALSRAE
DDSYAENVGIHWATEQVRGLLDHKVAGIHMYTLNKSKATRKIYESLGIRNFDSLS
>A0A2T2T3X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QH_7_62_13|TrEMBL
MKVTEHLDQAPEPLISYEIIPPKRGGSAEQILRVVEELMPYDPPFIDVTSHSAEVNYEKQ
DDGTWKRRVKRKRPGTIGLCAAIEARFDIDTVPHLLCRGFTREETEDALIELSYLGIDNV
LAIRGDDTGYEKPAQGDRSRNEHAVDLVRQIDDMNRGEYLEDLIDAESTDFCIGVGGYPE
THFEAPNLTWDIMRTKQKVEAGADYIVTQMFFDNEYFFDFVEQCRDVGIEVPIIPGIKIL
KRKRHLRSLPKYFHTEIPEELAAEVDAADPDDVEDIGVEWAIRQTRELMDAGVPCLHFYI
MSSAKTVKKVVEPLHEMA
>A0A0M9ECK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Magnetomorum sp. HK-1|TrEMBL
MKVTDLYKNKKNVISMEFFPPRNEKAAEKFGSIIDTLSEQNPDYMSITFGAGGSTRDGSY
QTVKQVMIDKSLATVAYIAGYGLSPEDIKAVLDKYKELGVETIFVIRGDKPNNENFQPHP
DSFLYASDMINFIKKNYNFTLGCAAYPEGHVEAESLEKDLEYLKLKVDNGAEYVVSQYFY
DNSYFFDFVKKCRSNGIKVPIIPGIMPVYTLKMTNMLSKVCGSSITDELQKKLDNVDSED
KEAVLELGIDFATNQCKGLLNEGVPGLHFYTMNRSKSTSEIISRLKQENLL
>A0A495QG19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura pelletieri DSM 43383|TrEMBL
MGFEVVCEVEPPTRPDLTRVRHQIGVLSPVADSFLIPDNHIGRATVSSVAVAHEVQAMGA
RGIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVYGDKPSVGGRTSELTVRAMMDEARDA
VFPGCEPFQVGVAAGLRKVPEWKRAADFMFVQVSYSMEKLLRWRESVGVDGPVYAGVMVL
ASAGMARRLAGAIPDIEIPEELVNAVERDRAAGVAAACEQVLAIRDSGAFDGVHLVPVSR
YREVAAVLERELG
>A0A166JFX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peniophora sp. CONT|TrEMBL
MKISKKVEKATKEDKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
ELTAELVKTCQGYIGIETCMHLTCTNMPKEKVDIALKEAKEAGCRNILALRGDPPMGSDE
WTSVEGGFEHGIDLVRHIRANYGDHFDIAVAGFPQHMLLPEEERAQEIKWFKEKIDAGVD
FIFTQMFYDVDIFISWVKAIRAAGITIPIVPGIMPIQTWNGFQRATSLAKTHIPQSFHDA
LEPHKNNDEKVREIGTRLVADLCRKILAAPLGIRGLHFYTMNLERGSRMLLEELNLVPRV
ETLKPLPWRQSLTPSRRSETIRPIFWANRTKSYLTRTENWDEYPNGRFGDSRSPAYGDLD
GYGASIKQTREDALRLWGYPASFAEVASLFRRFCTSELPALPWSDQAPSLETSVISTLLA
RMNALGFLTINSQPAVDGARSDDSVFGWGPANGYVYQKAYLEFFVRPQLLDVLISYLEKD
PSVTYYVINKRGDLRTNNTQEGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELWRQ
WSQIYELESSSRALLTGLTDELMLVNVVHNDYKSQEAIFKPFFLAGEKYASTHPNDAVVL
PNGTEHLLHNGDAIAHEGGTA
>T0HHN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium baderi LL03|TrEMBL
MTLSFPSVEEARRALDAPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLGPKFV
SVTYGAGGSTRERTHNTVARIAKETPLAAAAHLTCVAASKDEIAEVADAYWDAGVRHIVA
LRGDPPVAGAKFEAHPQGYQGAAELVDGLVKRHPFEISVAAYPETHPDAASAQGDLDNLK
RKLDAGATRAITQFFFEPDTFFRFRDTAAAAGISADIIPGIMPVSNFAAVQRMSAMCNTD
VPLWMGRLFEGLDTLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPEKSA
>Q3BYU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. vesicatoria (strain 85-10)|TrEMBL
MDFGSFPLDQCVVAMPPDHHDKTARPVISTDTPNFASTVTEAYSLEVSAKDIGALTNAAP
RILPGCAMFIPYLPGQNQAVRLAAAQMVRSLGFEPVPHLSARRIGSLGELQACIARLVDE
AGVTRCLVIAGDPSTPKGPFPDSVSLIETGVFERSGIRTIAVAGHPEGHPILRTTEQWEV
LERKCRSIQERGMAPLIVTQFGFDADIVVTWLEALRARGMTHPVRVGVPGPASVAVLARY
AASCGVGACASVLSNYGISIGKLFGNAGPDRFVDRLASRLTEAHGDVRLHLFPFGGIAQS
VEWVAHYRSRASQQDRMRSVRADQA
>A0A316HBJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter oryzae|TrEMBL
MKIPEHIANANGKTLFSFELIPPLKGQSIQGIYDAIDPLMEFKPPFIDVTTLREDFIYKQ
HPSGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENALIELEFLGIEN
VLVLRGDARLGDSSFVPTPNGHCYATELLQQVVNLNNGIYLHEDHGNTAKTNFCIGVAGY
PEKHFEAPNLKTDFKYLKQKIDMGAQFIVTQMFFDIDKYKEFVNGCRANGINVPIIPGLK
PITTSKQLVTLSKTFHIDIPEDLSDAIHACANEKAVKEVGIEWMINQCKELMAFGAPVLH
FYTMSNAGPTKRIAEAIF
>H0K3P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora azurea SZMC 14600|TrEMBL
MIVRTVVDRLTSGRRPTFSVEFFPPRDESDEAILWRSIRELEPLDPAYVSITYGAGGTSR
EGTIRNIARVATDTTLVPMAHLTAVDHSVAELRHVIGHFAAVGVRNILALRGDPPGNPMG
EWVAHPRGLTYAEELVRLVRELGDFCVGVSAFPYGHPRSTDLETDTHYLVRKLDAGADFA
IAQLFFEADDFLRLRDRVAAAGSDALMLPGIMPLTTPRTWRKTIELSGATPPRWLVERLE
PLSDDPKAFRAEGLDVITELCEQLLAEGVPELHFYTFNRSKATRELVDRLGLRAPRTQAA
VTGA
>A0A7J2S4F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon|TrEMBL
DYFVGAALIPTRKKEVEIYKKKIDAGAQFFVTQLTYDSKTVIDFIEKVNPSVPILVGSGP
ITSLKRLEFFRKQLGIPGLSDGIAKVLREAKDMGEKSVEICVEMYQSLRDFARSNGYSIG
AHIMSIRYPLLAAKIVKRISKL
>A0A2Y9QGD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delphinapterus leucas|TrEMBL
MDRPKPKVLPAGHCCPSLGMRAWEAGSARFSVPPSIRSSAMVNEPRGHGGPSPRWEGSSS
GSESSKDSSRCPTPVLDPERHERLREKMRRRVESGDKWFSLEFFPPRTAEGAVNLISRFD
RMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITGH
LHKAKRLGLKNILALRGDPIGDQWEEEDGGFNYAVDLVKHIRSEFGDYFDVCVAGYPKGH
PDAESFEAGLKHLKEKVAAGADFVITQLFFEADTFFRFVRACSEIGITCPILPGIFPIQG
YRSLRQLVKLSKLEVPQQVKDVIEPIKDNDAAIRNYGIEQALSLCRELLASGSVPGLHFY
TLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFAHYLSG
EPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGWG
PGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGDNITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQHIHDNYFLVNL
VDNEFPLDSCLWQVVEDTFELLSGPHQSKRETEAP
>A0A851PGJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anhinga anhinga|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTRDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYDLRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7U3D0R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon|TrEMBL
MTVKNVSNIGYIKSFELVSRRSYGYTEAQDAVDLLDGISNVITAPENPMGMPGIDPLMAL
YTATRGHDIIPIPHITPRDKNKLHIQSQVLTGLKFGINHFFAIGGDPIHKTMESREVREL
DVIGLIRAIKESRNYSKDFSSGTDISVGSSFNPFREAEEDIVKAKIGGGSGFFITQAFYD
SALLKREWVRKRDFKLIAGFMPIQKESQIEFMKKLGAKIPEETEKRILGAQDKVQESSRI
IKEMADDLDGYIDGIHIMPLGKNKIAKDILESF
>A0A423DY80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas vranovensis|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHIEIAAYPEMHPQARNFEDDLKNFVRKANAGADSAITQYFFNADSYFY
FVERVQQLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A7W5X0M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK602|TrEMBL
MALLGLLKDKQDEELVEPVAGLSDLTSGYSIEVTPRTAAKISDFKTLLPRGTRVYIAHVE
GTSITEMAETAKRLSTDGFPVMPHFPARMIPNVATLEDWIKRYRGEAGVDQALLLGGGLR
KPVGNLESSMQFIESGLFDRHGFKRLHVAGHPEGNRDIDSDGGYRIVDEALKFKQAYCER
SDAEMAIVTQFAFDARPIIAWAERIAAFGVKLPIHLGVAGPTKLQTLIKFAIACGVGPSL
SVLQKRARDFSKLLVPYEPVEILRDIAVYKAAHPESLIQQIHLFPLGGIGASAAWMSEQQ
RSVSVA
>A0A2Z4YEP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MVLKSEARGRNIRVSFEFFPPKSEEMEGQLWHTVSQLQDWDPDFVSVTYGAGGTTKAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPTFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGISRRETKSAGAAA
>R7JJY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes putredinis CAG:67|TrEMBL
MNITDLIQGAVASRTTRFAFELLPPLKGDGTRSVFGAIDPLMDFNPAYINVTFHREALKE
DIRPDGSREWHIMRRRPGTVGISAAIRRKYDVEVVPHLICGGWSKYDIEDSLIDMDFLGL
HNVLALRGDKRQNEPRFVPYAQGHAHAADLVRQIQAMNRGEFIDGEVEECHHSKFSVGVA
GYPEKHFEAANPQSDLQYLKEKVDAGADYIVTQMFFDNSKYFDFVERCRKAGITVPIIPG
IKPISTPKHLEILPRTFSVSLPEELVKAVRACGEDTQAAREVGIEWAIHQAKELKAAGVP
IIHFYTMGRTDNIRKIARNVF
>A0A1J4TU09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium CG1_02_37_35|TrEMBL
MKVIEHLLKAKEPLISFEIIPPKRGGDIKSLLHVVDDLSKYNPPFIDITSHGAEIVYEET
PQGIKKKIIRKRPGTLGICALIQNKYNIEAVPHILCKNFTREETEDFLIELNYLGIENVL
AIRGDDNGFVKPVPHGRSANEFAVDLVSQVNAMNNGKYLEENLLDAKATDFCVGVSGYPE
KHFESPNLKLDIKYAKQKIDAGAHYIVTQMFFDNNVYFDYVNACKEEGIDAPIIPGLKIL
SLKSHLTNIPRNFYINIPEALAEEVMSAKPEHVLEIGVNWAAKQAEELLNRDVPSLHFYI
LQNSKPINLLMKKLNLHFKKLVVKK
>A0A512BHP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Segetibacter aerophilus|TrEMBL
MKVIDHLNQAKDTLVSFEILPPLKGKSISSIYDHLDPLMEFKPSWINVTYHRSETMFKKK
SDGTFEKVEVRKRPGTVGICASIMNHYKIDAVPHFICGGFNKRETEDALIDLNFLNVENV
LVLRGDAAKNEASFEPEPGGHSYAIDLLKQVLDLNNGIYLDEDIRNGGKTNFCIGVAGYP
EKHFESPNPEIDLQRLKEKVDAGASYIMTQMFFDNQKFYDFQKACRAIGIDAPIIPGLKP
ITSKKQLSILPRIFHVDIPTDLSNAIMRCKNDQECEIVGQEWLTQQSKELKKFGVPVLHY
YTLGKPKVIWNVVKEIL
>A0A2V4VQ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PP-WC-1G-195|TrEMBL
MSTRTLYPAERGDLRLSFEYFPPKSEEMDTQLTRTAAILNAYAPEFVSVTYGAGGSTKAR
SLTTVRRLIDDCSIPGTAAHLTCVGATRAEVDAVVEEFAAAGVRHFVALRGDPQGGIGAQ
YQPFPDGYENAAALVAALSRSGRFQISVSAYPEKHPESSDVDADIDMLKRKVDNGATRAL
TQFFFDNNDFERYLERVRKAGISIPVVPGILPINQFGQVSKFAGLCGARIPEALSARLAH
LDESPEERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFKRTDEAVVE
GADA
>A0A2T6D2K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutus sp. ER46|TrEMBL
MPPDRPISDLFAQRRPLRSLEFFPPKDDAGVAALRATATALRRMQPDFVSVTYGAGGSTR
ERTSQVSDLLKAEFGYTVMPHLTCVGHTRAELEAIADQIHARHFRNVMTLRGDPPKGATR
FEVTRDGLRFASELVALLKARHADLCLGVGGYPEKHPEAPSPEADLDHLRRKVDAGAAFV
TTQLFFDNAVYYRFVERCRAAGITVPIIPGIMPVQSLKQIQRFTSMCGASLPARLITRLE
AAADETDVVEAIGIDWALTQIRDLLAQGAPGYHLYILNRAKAALTLAAGLAA
>A0A2M9IL30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB01373|TrEMBL
MGTSLLEDFSLEMTGKDIPKLEEAHPAIPPGTRINITFLAHEDLATRLAAARAVERLGFV
PVPHISARRLRSRTDLERFLAGLRDDGTVENVFVVGGDPVRAEGPYEDALAVIRTGLLQH
YGVRHAGISGYPEGHPAIADHVLWSAMADKHAALGAQRLAGDVITQFGFDVDPVLAWLEG
TRTRGVGLPIRIGVPGPAGIKRLITYAARFGVGTSASITKKYGFSLTNLMGTAGPDRFLR
ALAEGYDAGRHGVVKVHFYTFGGIGATSEWIARFREEGLT
>A0A8B3MH26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium meliloti|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVNERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHERCYILVGVG
PMASAKTARWIRSNVPGIHIPDSIIKRLEGAQDQKKEGKQLCIDIMNEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLRGRKPWTREAAPTDALVAERLEHIREGKEENQQQMAEAAAH
HPH
>A0A6P6AAK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Durio zibethinus|TrEMBL
MYIGLLSGNSVISATPTPTRFSLKYCQLNFPRSRTSISLPISNPIIQFKMKVIEKIQSLL
EDQGKVVFSFEFFPPKTEDGVDNLFDRMDRMVAHNPSFCDITWGAGGSTADLTLDIANKM
QNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQVEGGFAC
ALDLVKHIRAKYGDYFGITVAGYPEAHPDAIGSEGVATPEAYQNDLAYLKRKVDAGADLI
VTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPDEITAALE
PIKDNEEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLGLIEESKISR
FLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSRNPSYGALSDYQF
MRPRARDKKLHQEWATPLKCIDDIQEKFKNYCLGKLRSSPWSELDGLQPETKVIHEQLGR
INLKGFLTINSQPAVNGECSDSPSVGWGGPGGYVYQKAYLEFFCSMEKLDALVNKCKAFS
SVTYFAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFMVWKDEAFEIWSRS
WAALYPDGDPSKKFLEEIQSSYYLVSLVDNDYMSGDIFAVFEDL
>A0A847EK51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidales bacterium|TrEMBL
MTLRSAIENKEFIITCEVGPVKGTNIEEIEESCEVLKGKVTAANITDQQSSAMRLGSLVT
SHLAKERGIDPIYQVTCRDRNRIALQSDLLSASVLGIENVLALTGDLPSLGDHPHAKPVF
DLDSVGLLGAIETLNSGFDMAGNELNGKTNFFPGAVVNPGADTEASYEMQIRKMEKKIRA
GAKFIQTQAIYDVDLFDRFMKRVAGFGVPVLAGVIPLKSVGMARYMNKSVAGVFVPEDLI
QKLKNSEDKTAMGIQIA
>A0A2N1PTY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Wallbacteria bacterium HGW-Wallbacteria-1|TrEMBL
MNFREEILNRVVVFDGAMGTMLYNRGVFINQCFDELNITNPALVEQIHIEYRDAGVDVLE
TNTYGANRFRLAPYGLREKLRELNLKGVEIARKVAGDNMMVAGSVGPLGSPLEPLGKISP
AEAMEAFTEQIEILIEGGVDLILLETFPSLPEIELALQAARKITDLPILAQMSVDEDCNA
LFGTSPEVFARRLQELGADAIGLNCKVGPASMLEAVERIAAVTDLPISAQPNAGRARVVE
GRHMFLCSPEYMAEYAKRFIQTGVRIIGGCCGTTPAHMRAVVSAVRASSSGRIDNISRRI
SVNEPHGTEALQQSEGKGLTERKPAGPDVWARKSAFAGKMAEGKFVVSVEITPPKGWKYT
SKLKGIEALRDMGVDAVNIPDSPRATAKMSCLAFAVIVQRETGIETIMHYTCRDRNLLGM
QSDLLGAYALGIKNVLAITGDPPKLGPYPFATAVFDVDSIGLVSTVDTLNSGLDLGGDSI
GSPTGFLVGVGANPGAIDLDKEVERFEMKVRAGAEFAMTQPVFDPATLRVFLKRIQDFRI
PVIAGVWPLISLRNAEFMNNEVPGAQVPDSLMERMRRAATAEEQRSVGIRIAQESINEIG
DLVQGIQASVPLGKYESTMEVLSVIPGFENGFRDYREKKASTANDPK
>A0A847FAL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidales bacterium|TrEMBL
MENVSVNKYRDSLNNPERFTVTWEQIPGRINTRQQLNSILTNTAEAAAGGIVTTISITDS
PGGTPALPSEVVALEVQKLGIEPLVHIALRDKNRTQVESILYNLNLNNIRNVLVISGDYP
EVTSYMGRALPAYDLDPAHVMDLIRCLNSGREYEALGKPRQMEPTDFFGGVGVSHFKQSE
AETVCQYFKLEKKIKSGAGFIISQIGYDARKMHELVTWLKYMDYKVPVLANIYLLSYPAA
KAMHVNRIPGAVVTKELLEEVELERQAPDKGREKRMIRAAKMYAMAKGMGYAGVHIGGYH
LTHKDMEYIVNLGNELEPRWQELVPEFSYPQPDGYYLFEKDEQTGLNTMEETGLLGKGKA
PFSYRIARIIHEGFFDPRHPFFSLYQKMAARIDESDLSRRAFGKLTHIAKTMLYNCLDCG
DCALFDTAYLCPVSQCPKERRLGPCGGSHEGWCEVYPGKKQCIWVRAYERFKHYNEEDII
GSYIVPPRDWTLWQTPSQLNFYLGRDHTSKRLGLEPPQPKSKE
>A0A1S2EY92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. LC231|TrEMBL
MKPNLRKAWENQVLVGDGAMGTYLYQKGFPVGISYEELNLTSPEVIGNVHRQYVEAGAQV
IETNTFSANYDKLSKYGLEAKVGEINRAGVRIAREAAGDSGYVVGAVGSIRAGKRSNIST
SELKRYFEEQLSVLISEGVDGILLETFYDVDEIQLALAQARMLSDLPVICQFAVEDIART
LDGFTMPDAYRILSQEGADVIGFNCRTGPNGIMRALETLNGIMNLPASVYPNAGIADYVD
GEYRYGASPEYFGKTALEFADRGARIVGGCCGTTPEHIAEISSALSGYVPAPLPIVEEAE
VNRIVIHETAQEQFYERSGEPTIVDIVKERHTVIVELDPPRDLDITKFMKGAEALKKAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVVGAAFNP
NVRHLDKAVARLEKKIASGADYVMTQPVYDPELMVRLREATAHLDIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAMGVKIGKELLDVATGHFNGIYLMTPFMFY
EMSVQLMEYVWEKSGRRLTPLFH
>A0A1Q2U167|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. NIES-970|TrEMBL
MTSRLRRAIENREFVVTAEVAPPKGGDPMKMLQMAKILGDRVHGINVTDGSRAVMRMSSI
AASTILLQNGIEPIFQMACRDRNVIGLQADLLGAQALGLRNVLALTGDPVKAGDHPKAKA
VFDLESVRLLKLINKLNGGQDFNDKKLPDGPLALFPGGAVDPQLKSWYAIESRFARKVEA
GAKFFQSQMITDFNRLEEFMTRVASQYDAPVFAGIFLLKSAKNAQFINRCVPGAQIPDAI
IERLAQAENPLEEGMKIAAEQVKIAKNLCQGVHMMAVKKEDLIPQILDLAGVSIQNQIKP
MLV
>A0A6P1NIE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter psychrotolerans|TrEMBL
MSPPSLIETHPNLSETAPVALSYELFPPRSPAAAESLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPEELAEIIGDLLDTGVRGILALRGDQPKG
GAPLAAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYANLISRARRAGVTIPIIPGVMPLTSLRRVTRLGELTGVE
PAPELLARLAAADSDSERLRIGVRATVDLANAALEAGAPGIHIYTFNEHQSALEVLDKLA
LPRQSRSVGRRSATLRRQLAS
>A0A2Z4JV66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter paneuropaeus|TrEMBL
MELSVEFFPPKTPEGENKLRLVRERLSEVLKPAFYSVTFGAGGSTQSGTLKVVSEIHAAG
AMVAPHLSCVGSSRESVCQMLKQYQSLGIKRIVALRGDLPSGMGQYGEFHHANELVEFIR
SETGDWFHIDVAAYPETHPQAKSPASDIDFFVQKMKAGANSAVTQYFYNTDAYFRFVDEA
YEMGVTQPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDVASIRAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLSLGS
>A0A258FUB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas subvibrioides|TrEMBL
MLDVTRSDSQPGRDARIGSLLQGHSLEMTAKDVVALEEAAGVIPQGTRIAIAFLPGETFE
ARLHAAVRVRSLGFDPAPHISARRIASESELRGFLENLSTQASIQRLFVVAGDPPVPEGP
YEDALSLIRSGMLNDLGLESVGVSGYPEGHPDIGEPALWGAMFDKRDALAELGISMTILT
QFGFDAEPIVHWVERVRSHGIDALIRIGVPGPAGIKTLLRFAARCGVGASAKVMSKYGLS
LTQLMGTAGPDRLIEDLADRIDPARHGPLSLHFYPFGGIARTAEWVSDFAAKKAA
>A0A3M0U661|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium gottingense|TrEMBL
MRGTFAPTRLSASAPIDRVGEDTTQQRRRTRTALSFELIPPRHGADEGKLDELIAGLAAY
RPDYVSVTSSRRSDWLTGTAALIARVAETTNLRPIAHLACTAGTREELVTWIRALIDAGV
RGFLALRGDLPETGMPADHLQHATDLLNLIQDVEDEEAFRLAAGKLALSVACYPSGHAES
KNFDEDLDVLLSKQRLGADFAITQLFFNAQDYLDFVEVARLAGVRIPLIPGIMPMTSLKR
VQRMGELSGIEVPECVARTLAQATTPEEEYELGMQMSARLANTILDAGTGGLHVYTHNNL
AVTQDLLSRIGIPQRADHSPQ
>A0A291PDS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter tropicalis|TrEMBL
MSLSRLSVELIPRSTEALLDDVASVKALFPATDTLNVPDLMRFPLRSWDAAALIRPHFAR
VVPHIRAIDIAPDAPLPGADQPGLEEVLVVHGDPPADLSHRTYPNSTESIIRRYKKEAPH
LRIYAAFDPYRRAPWQELEDVARKKEAGAEGFFTQPVFDLKLFDLCREWLRDETVFWGLS
PVIGPRSRSYWETTNHVVFPKDFEPTLEANIQFAQTVLRHLSQEKGRAYLMPLRVKLDQY
LPPLIEALA
>A0A1M5T5P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidimonas bauzanensis|TrEMBL
MSSTKAISLEFFPPRDIAAQEKLVRSAKQLLALHPAYVSVTFGAGGSTRTGTADTVRLLQ
NLGCDAAPHLSCIGATRAVLADILDSYREQGIRRIVALRGDLPSGMGGDQGELHYASELV
AFIRQHSGDWFHIEVAGYPEMHPQAPGAAADLDHFVNKVRAGANSAITQYFFNADAYFDF
VDRSRAKGVDIPIVPGIMPITNYAQLARFSNMCGAEIPRWIRLRLADFGDDKASIKAFGV
EVISRLSQDLLDNGAPGLHFYTLNNAEVTMAIWRQLRLD
>A0A2N2DJ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-13|TrEMBL
MTSFRDSLGKFTITCEVGPLKGCDISEIIEVAELLKGKVHAANVTDQQSSVLRLGPMVTS
HILMDHGLEAVLQMTNRDRNRIAIQSDLLSAAALGIENVLSLTGDYQSLGDHPQAKGVFD
LDSVQFLAAVKTLNEGKDLSGNKLHGVPNFCAGAVVNPGADTEAAYELQIIKMEKKAELG
AKFFQTQGIYDFNTFEKFMKRVSHISVPVLAGIIPLKNAGMAKYMNKFVSGVFVPDHYID
RMAKAEDREKEGIKIAAELIKGIKDMCQGVHIMAIGWEKAVPDILAESGLA
>A0A223QFW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis dassonvillei|TrEMBL
MAPRGPAPRPRHIRELLDAGEPMFSFEFFPPRTPQAQERLWRAIREIEALGPAFVSVTYG
AGGSTRGLTVETTERIATDTTLLPVAHMTLVDHSVAELRHLVGRLADAGVSNMLAVRGDP
PGDPDGEWIRHPRGLTYAEELVRLIKDSGDFCVGVAAFPYKHPRSADVETDTDHFVRKCE
AGADYAITQMFFDPEDYLRLRDRVAARGCEVPIIPEVFPVVRTSFIPRSEQLSGAPFPAD
LAEKFASFGDDDESVRAFGIEHAQRMCERLLAEGAPGIHFITSNRSTATRQIYREISGHR
SPSGEAGRP
>A0A524BH17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium mxb001|TrEMBL
MSRLSDLLASGARPVVTAEFPSIDGGGLAAVERAADELRPFVDAVNATDNPAAHAHASNT
SIAIGMLQFGLEPIMQVVCRDKNRLAMQADIMGASLFGVENVACLTGDDVTAGDEPEARR
VFDLDSTQLIKVASGLAEGHYLSGRAIKEPPALFVGAVENPFAPPLDYRVLRAKKKAEAG
ARFLQLQIGYYPERPEAFVRGCVEQGVTQTTALIPTVVLTKTARALTFMNDSVPGISIPA
EMIERVAGAGDKDAVAEASYQLTLELSQHALSLPGVSGIHLTDFRHDGSLERLVRDLGIG
PAFDPVATVAGTTAV
>A0A4P8EKP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodobacter turbinis|TrEMBL
MSKTPNISFEFFPPQTLDASFRLWDTVQTLAPLAPKFVSVTYGAGGTTRKLTHEAVGAIG
KNYGLNVAAHLTCVDATRAETLEIADSYFDAGVTEIVALRGDAPKGAEKFTPHPEGFASS
VELVEALAATGKFKVRVGAYPEPHPDSADTMADVRFLKRKIDAGASSAMTQFFFEAETFL
RFRDACAREGITAPIIPGILPIQSWAGTKKFAARCGTKVPAWLDEAFTAAIRDGREELLA
TALCTELCDTLMAEGVEDLHFYTLNKPHLTREVCHALGVNPQVGLQNVA
>A0A292PLB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tuber aestivum|TrEMBL
MVHIAPKLAAEHEKNGKPTFSFEYFVPKTAQGVQNLYDRMDRMNQLGPQFIDITWNAGGR
LSNLTCEMVNVAQSVYGIETCMHLTCTGMPKSKVDNALKDAYKAGCTNILALRGDPPREN
EKWEADPHGFRYAKDLVKYIKANYGNHFDIHVAGYPEGCDDGTDPELLLEHLKEKVDAGA
SSIITQMFYDADIFLDWVKKCRDVGITVPIIPGIMPIHTYAAFMRRATWTKCHIPEKWLR
LLEPVKNDDVAVRDIGRDLMVELCQKIIDAGILHLHFYTMNLATATRMCLEGLGIVPSLE
QRTKALPFRPSLGLNRKEENVRPIFWKNRHMSYVQRTQEWDEFPNGRWGDSRSPAFGELD
AYGIGLRGSNEANIKIYGYPKTIRDISELIKQYLTGNLPSLPWSEGYINSEADTIRDELL
KLNERGFLTINSQPAVNGVKSTHPVYGWGPPNGYVYQKSYLELLVSPEQLAELITRIERD
PDLSYHAVDKNGTLKTNSSEGPNAVTWGVYSGKEIIQPTIVETISFLAWKDEAFRLGDDW
AKCYEADSVSRHLIQEVMDTWFLVNIVDNDFHQSQKIYRLFDGMEVPKMDESLANGLTSA
>A0A2M7XUC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium CG_4_9_14_3_um_filter_48_9|TrEMBL
MKVIEYLEKATETLISFEIIPPMRGRSAQEVYTILDQLIEFEPPFIDVTSHAADAYYVEQ
KDGSFKRYIKRKRPGTLGLCAGIKYRYKIEAVPHLLCRGFTREETEDMLIELNYLGIENL
LAVRGDDPNYQKAINPDRSKNNYAIDLVRQVADMNRGRFQDDILDSAQTDFCIGVGGYPE
KHEESPNLEADIRHLKEKIDAGAHYAVTQMFFDNQYFFDFEKKCRDAGITVPIIPGLKLL
TKPYQMKSLPSNFHVNIPDTLVAAMTAADSETEAQQIGVEYLKKQAGELINAGVSCLHFY
VMNDVHLVKEVVRSLK
>A0A1F1UVP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC08F01|TrEMBL
MFEASPSTRLSASAPIDREGAPVIRRPRPKRQRTALSFEIIPPRPSDSVAKMDELIAGLA
AYNPDYVSVTSSRRSEWLEGTAAVISRIAETTDLRPIAHLACTAGTREELTEWIRTLIDA
GVRGFLALRGDLPETGMPEHYLQYATDLLNLIEEVQEEEAFRLAAGKLALSVACYPKGHE
ESRNFDHDLDVLLTKQRLGADFAITQLFFEAQDYLDFVEVARLAGVRIPLIPGIMPMTSL
KRVRRMGELSGLEVPEVVEKQLLEADDEYETGMQLTAKLAREILDAGTGGLHVYTHNNLA
VTRGFLDRIGIQ
>K2PPD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Galbibacter marinus|TrEMBL
MKVTEHIEAAQNKTLFSFEIVPPQKGKNIQELYDNIDPLMEFNPPFIDVTTSREEFVYLE
KDGLYDRKVTRTRPGTVGICAAIKHKYKVDTVPHVLCGGFTKEETEYMLVDCQYLGIQNV
MALRGDAMKHQRYFEATNGGHTYAYELVEQIRNMCQGKYLHETLENSNTDDFCIGVAGYP
EKHLEAPSLEFDLKKLKQKIDAGADYIVTQMFFNNSKYFEFVEKARQAGITVPIIPGIKP
IAVKKHLQLLPQVFKIDLPEDLISAVDACKNNKEVRQVGVEWCIAQSKELKEAGVPVLHY
YSMGKSDNIKNIAQALF
>A0A3M0A6S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Umboniibacter marinipuniceus|TrEMBL
MFQGAHELRAQRQARSSHPAPKVSFEFFPPSSPAIEETLWKSVARLKTLAPEFVSVTYGA
DGSTRDNTHRVIKALGEQTVIPTMPHLTCVDASKSEVDEVADSYWKMGVRSIMALRGDPA
SGAGSVYTPKADGYHYAADLVAGLKRQHDFRIGVAAYPETHPEAPSAHFDIDNLKRKFDA
GADFAISQFFFSTEAYLRFRDRCVLAGIDKPIIPGILPVTNFNTLKRFAGACGTELPRWL
SDSFEGLDNDPETRQLIAANIAIEQVLALQNEGVNDFHFYTLNRAELCYAVCHSLGVRPA
VELA
>A0A8B3IF48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas xanthomarina|TrEMBL
MTALNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKARAGADSAITQYFFNADCY
FYFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQA
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>C2V0K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus Rock3-28|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTNRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQVALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKVQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVVLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7V7HEI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. SH5-2|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTEKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRQQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLVDYGANVVGLNCQLGPLHMTEALKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMAPKFIEQGVRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDTAMKYFNGVYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7V3NZM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLLKEKLERGKLVVTCEINPPKGVEVAEQIKELDSLKGRVDAVAVTDNKSSVMTMSALIF
SYFLKERGFEPILNLSCRDRNRLALQADLLGAAALGIQNILVVTGDYASMGDHPQAKPVF
DLDAVQLLKTLQILKQGQDLGNNLIKGKPVFFPGATVSPVPSTEAALELQLIKMEKKAAA
GAKFFITQPIFDLRALDNFMKRAVKFKVPVLASILPLKSVSMARFLNKNMPGIFVPEEII
NELGNAPDRVKGGIEISAKLMRSLPGICQGIHLIPAGWEKFLPAILEAARI
>A0A7Y3A880|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MALFGKTVVQGTAEALAYRRKLIDEMVFELIPMKSADAAIAALPPNSPVSVTASPVKGLD
ATMELADRIRDAGHRPVPHLSARLTEGPAHVARLANWLRTEGYESVFVVAGDAEEPVGPY
DGAHAFLTDLLAQDHGLKRVGITSYPDGHPIIPTHICDAQLLLKQELLAEAGVDGWASSQ
MCFDTDKLSAWLRRERDRGFTLPLHLGIPGVIDRAKLMTMGVRLGVGASLRYLKKNRAAV
TKLMTPGHYDLDDVLVPMAEDLESLGVESLHVFTFNQVESTDAWRQQVLSEGAQN
>A0A7C7ZSF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
PRLFVGAAANPFADPFEIRVPRLAKKIAAGAEFIQTQCIYNLEKFELWMKLARDRGLHEK
VYIMGGVTPLRSAGMAKYMKNRVPGMDVPDEVVARMAGVPKEKQAQEGIDICVETIQRLK
ECEGVRGFHIMAIEWEEKVPEIVERSGLYPRPSHS
>A0A7C7TN88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MSIFSFSGRLDRSTAASLRRQLLSDAHFEVIPLKNLTEQLQHLPVGASVSVTASPNKSLD
DTWKLAKDLLVRGFRPIPHLASRMLESRQQLDRLIKELAELGLNELFLVGGDAPSPHGPY
EDSIQVLQAILGFEHKLEHIGVTAYPDGHSFIETAVLSSSLRAKQEILNEAGLASHAATQ
MCFDPNTIRGWLESERASGLEIPIHLGIPGAVERKKLLSVGARLGVGASLRYLQKNTGTL
ARMVMPGGYNPNKLLSPLAGDLQRLGVQGLHIFTFNQLDATVAWRNAAISSLKT
>A0A7V5R9J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEAREKRTPVSRLERELDEGRFVITAEICPPRGTETTDFLARARLLKGMVTAANVTDNQR
AVMRLSSLACSVLLLDEGIEPVFQMTCRDRNRLALQSDILGAWTLGARNILALTGDHVSF
GDHRESRAVFDLDSVQLVGTVRTLNEGRNLKGRELRGGTGFFIGAVVAPEADPPEPEMIK
FEKKVDAGARFFQTQAFYDMDNFKRFFEKAEKTGAKILAGILLLKSARMADFLNRKVPGV
TVPRRLIDELEAAPDQLQKGIEIASRQLRELKTFCHGAHIMAIAQEESVPHIISGA
>A0A661RNJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLRVFQHDLRDPAHFVITLELVPGRESTGRKIDTVMGIARDAMADGRVSAVSITDNPGGN
PSLSPDVIGNEIFKIGLDVIVHFTCRDMNRVGMESRALQLAMMGMKNILALTGDYTGAGF
GGQGAPVFDLDAVSLLAMLAMLSERIEAAGDPDGFFAGCAVSPFKLTPGETMAQYAKLCR
KEAAGAKFVITQLGYDAGRFAHLLDVTRSMGFDLPVLGSVYLLTPKAARIMNAGRVPGVV
VSDQLRERVLAEWRDRETGRQAAVERAARLAAVLKGLGYKGIHLGGIHRDFSVVARILDR
LERIEDRWTEFLADFGMAAAQEPAAPAAGGEVCAMVDGPAPALGPLEKLHFNLMRQAHGM
FFARGSASAGLWRTLARRLDSHRAGRLIASTLEDPVKRLLLGCRHCGDCGIVHLAFLCPE
SQCPKHTRNGACGGSRNGRCEVHPERYCVWYRAWRRWAAAGESRRLAEGCVPPRRWELNE
TSSWLNFHLGRDHQGSGDAFARFCRSRSCRTEALANAADQIRQ
>A0A7V4G103|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
LVTKVRAGVDFIITQLFFDNRLYFDFVKRARAAGITVPIIPGIMPITDAAQIQRMTQMCG
ASVPAVLRAEMERRRHDPIAMTQLGVAQATAQCVDLLLGGAPGIHFYTLNQSPATRMIMT
ALRVRL
>A0A7Y4U1S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKIRDLFQTQAQTISFEFFPPKTPEDVDVLFDRMRELRALGPSFISVTYGAGGSTRRNTI
DLVCRMQEEVGIVAMAHLTCVGHSQTELREVLRELQDRGVENLMCLRGDPPQGETTFVPT
PDGFSHAAQLVTLARSLDDFSIGVAGYPEPHPECADKALDLRHLKEKVDRGADFVTTQLF
FDNSDYFDFCRRARDVGIKTRIIPGIWPITNYKQIVRVAKMCGATIPEALRRKLEPVADD
TQAVFEVGVEWSWRQCEELLAGGAPGIHFYTLNRSLATQRIFERLRHSSVRSLLPGITKA
A
>A0A7Y1UPE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MVVGIDRRTQRRNRRSIKDLDDSGRSRLRRLLESSWLVVLPTSEIIPLVESRNPPGSVSL
AVACTDGLGVDQTIAVSEVLAARGYRVTPHLAARQFRSERHLNETLQRLAQRSINRILVV
RGRTPTAGPFRTAGALLEAVKQHPDTPAEVGVAGYPEGIPAVDRERLAERLLRLSSWATY
VSTEVTVSPERLLRWVAEMRVRGLEVPIEAGIPGVVRSVESMGKSSSVRRRDGGWYNPTR
LVAHLAAQPALDRLDVGGLRIETENHIERTASWRQHAYDLAHQPRTV
>A0A661N3Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEKRPFLSALKAGALVFDGAMGTALYERGLLYTRSLDAAVLDRVDAVKAVYEGYVLAGA
NVLTTNTFGANAYRLEPHGLADQVQAINHAAVDVARAAAGPSQYIAGSIGPTGLILKTLD
ADSADPIRAAFREQAAALSERGIDVLVLETFRQPEELELAIEGAKAGSRGAVPIIASCSF
DTFGTMADGTGPEKMAGILVEWGADAIGVNCADGPAGVYEMASRMLGAGVPVVAQPNAGL
PHRVEGRFAYKATPEYFQIYARRLYKAGIHAVGGCCGTTPDHIKKIASAARMVDGGGAAV
GLGGGMREDRESTRPIAPGATVVPLAEKSELGAKLGKKFVISVEVNPPPGLSLEKAMAGA
KLLRDGGVDVINVADGPRASARMGNLALCARIQNELGMPALMHVTTRDRNLLGLVAHLLA
AHEFGVNNLVVITGDPPKMGDFPDATAVYDTDSIGLLRVVNELNHGFDPGGKPIGAATAF
LSATGAEPAAKDYDRELSRLQQKIDAGAEVVMTQPVYDPAILERFLADTEGFGVPVLVGI
LPLASYRNAEFLHNEVPGMQIPEAIRDRMRVAGGGPTGRAAGVEIAREMLSSVKDRVAGA
YIMPPFGRYALALEVIDGIV
>A0A7K2B9U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MTVPSGSRSGLDRAGRAAVRRILEHPKFEVLPLKNVLDQVRWLPEGATVSITASPTKTLE
DTMDVAAELRLRGFQVVPHLSARMTHDKTHLAALLGRMDELEISRIFLVGGDAPQRGIFP
DAYSLLLAMDDLGHHLTEVGVTSYPEGHAVIPDAKLWQALHDKQPYASYLTTQMCFDPEA
IGDFISGCRADGIVLPVRIGIPGVADRLKLIQISTRIGVGQSVRFLSKHRGLVTKFIKPG
GYAPEGLLEGLAPLADDPAAAILGVHIYTFNQCETTERWRQEYLATL
>A0A538PFE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGSLLYERGVLHTRSYDELNLSQPELIRTVHRDYVHAGAELIETNTFGANRIGLARHGLA
DQAKAINRAGVELARSAAGDRAYVAGAVGPSGVNHGIASASERRLARFALAEQIDTLVLA
GVDAILLETFTSILELEMAIDVARERGPRVPVIAMMVFGTDLRSDGGLGPAEIADRLVAA
GADVVGANCRVGPAELYQVAVGMVGHGKPVIAQPNAGLPASVEGRTLYVANPEHFGVFAR
RMLKSGVRLVGGCCGTTPEHTRAMLGAVRMLRGEKLDERIAINPSAGPSAGDGHAAAAAG
PAPPAKTPLAERSRLGGRLARGEFLVSVELTAPTGADLGKTRQQVAELAAGGVDVVNIAD
GPRASARMANIAVCARLAAETRVEPILHVCARDRSFLGLIAHLLGAQGLGLRNLVIITGD
PPKMGDYPFSTPVYDVDSVGLLRIAAGLNAGIDPAGKECEPTSFVLATGAEPAAADRDRE
LRRLEDKKAAGAELVMTQPVYDPRTLERFLDDVGGLGLPVMVGVLPLASHRNAEFLHNEV
PGMGIPAEYRERMARVGGGPAARAEGIRIAQEALAAVKQRVQGAYVMPPFNRVESALAVL
EVARDRWRPA
>A0A7V2YDF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MPMPFAEALKTKEFVVTAEVGPPKGVDIQEMLHNIELLKDKVDALNVTDNQSSVMRIGSL
PVCKLIKEAGGEPILQMTCRDRNRVALQSELLGAYILGIRNVLALTGDYITVGDHIEAKP
VFDLDSVLLVKLIRQMEQGKDFAGNELKGAPKFCVGAIVTPEADPIEPQLLKFEKKIKAG
AEFIQTQAIYDLENFKKFMGYARKFDVKILAGIVLLASAGMARFMNANVPGIFVPQELID
ELVAAPKGKALEKGIEIAGRMVRQLREEKVCDGVHIMAIGREHLVPEILSAAGM
>A0A7W1MM10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGSLLYERGVLHTRSYDELNLSQPELIRTVHRDYVAAGAELIETNTFGANRMALARHGLV
EQCTDINRAAVELARSATGDQAYVAGAVGPTGAKFGIASASERRLARFALAEQIDTLVLA
GVDAIMLETFTSILEMETAIQVAKERGPRVPVIAMMVFDGAAKSDGGLGPAEIADRLIAA
GADVVGGNCGVGPAELYQVVVGMVGHGKPVIAQPNAGFPASVEGRTLYVANPEHFGVFAR
RMLKSGVRMIGGCCGTTPEHTSAMLGAVRMLRGEKIDEHAGSGHSAPGASAISASRGPVA
PPKIALAERSRLGARLTRGDFVVSVELTAPPGSDLTKTKQQVADLAGGGVDIVNIADGPR
ASARMANVAVCARLVAETAVEPILHVCARDRSFLGLIAHLLGAQGLGLKNLVLITGDPPK
MGDYPFSTPVYDVDSVGLLRIAAGLNAGVDPAGKECEPTTFVLATGAEPAAHDRERELRR
LEDKKLAGAELIMTQPVYDPRTLERFLDDCAPLGLPVMVGILPLASHRNAEFLHNEVPGM
AIPAEYRERMAKVGSGPAARAEGIKIAQEALAAVKHRVQGVYVMPPFNRVDAALAVLEVA
RDRMKPTAT
>A0A7W0KWD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MARVSELLASGRTFSFEFFPPQSDAAQLTLGRTIAELEPLQPSFVSVTYGAAGGTRQRTR
EVVAWVRRETAITPMAHLTCQGHRRREIATLLAEYRDAGIDNILALGGDPPADPADARPS
DYRYAAELVEDIQQLEHFSIGVAAHPDGHPRSPDRETDRRMLAAKLVRADFAITQFFFEA
EHYVRLVGELAALGIDKPVLPGIMPVTNISQITRMARLSGAAVPGWVTARFDGLDDPSEV
RRVGVSLATTLCAELLAAGAPGLHFYTLNRSTATREIYANLGLGVA
>A0A841DRV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella solani|TrEMBL
MANGLPSTLPGGAPTIRELLRSGGRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGAGVRNLLALR
GDPPGGPNQPWVAHPEGLNHAVELVELIRSLGDFCVGVAAFPDKHPEATSLAADAAVLAA
KARAGADYAITQMFFGADDYFRLVDRSAALGCDMPVLPGVMPVTNIKQIQRMAELTGMAL
PTAVTERLLAVEDDPRAVREAGIEIATELCERLLAGGAPGIHFITLNRSTATRQVFRNLG
ASVVS
>Q6HDR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis subsp. konkukian (strain 97-27)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7S0GQ30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amorphochlora amoebiformis|TrEMBL
GDVSTPPSLFPAVRPRPVPMSSTVVQGNKIIDKINERLKRGEQFFSFEYFPPKTEQGVKN
LDKRMTSMAARGPVWMDMTWGAGGRTSDLTLTLCNKIQNEKKVDALMHLTCTNMEQKKID
DALTECKKTGVRNILALRGDPPHGEERWTATEGGFSCARDLIKYIRKKTGSHFCISCAGY
PEGHPNVRKVITDSKWDPQTNTPKYWAVRKTKDGKYEGVSPKDWETEQNYLKSKIDEGAE
FIVTQLFYDLDIFYAWVKDCRARGIN
>A0A2G6N4L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSNLERILRAGHFAFTGELGPPRGSNVAAVREKAQPLVGNVDAVNITDNQTAMVRMS
SWAASLIAIEEGLEPNYQMVCRDRNRLAMQADILGASALGIRNMLCLSGDHQQFGDHPQS
KGVFDIDSTQLIGTVKKMRDEAQFLGGADIDGPPQIFIGGAANPFAEPYAWRVHRLAKKV
AAGVDFVQTQCIFNMDRMRQWVKAAVDMGLTEKVYILAGVTPMKSIGMARYMQNKVPGMD
VPNEIIKRLQGVDKKKVADEGIKIACEQIEEFKEMEGIAGVHLMAIEWEHKVPEIAQRAN
VLPRPVV
>A0A496Y911|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKNASRLKRVLDAGEFAVTAECGPPKGADSEVILKKGEKLKGYVDAVNVTDNQTAIVRMS
SLAACALLKSAGLDPVLQMVVRDRNRIALQSDILGASALGIRNVLCLSGDHQCFGNQPQA
AGVFDLDSIQFVEAVRNMRDMGVIVGGEALDGAPDLFIGAAANPFGDPQGFRAIRLGKKV
RAGADFIQTQCIYNLERFETWLRMAHDKGLTEKTAILGGVTPLKSAGMARYMKNKVSGMD
IPDAVIKRMEGVSKENQREEGVRICVETIERLKELNGVRGVHIMAIEWEEAVAGIVEKAG
LFPRPALGEG
>A0A2E5PS01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MITNIKTLEQTLQANEFAITAEIPAPISASAAEMEEKIDLLAGHVHAINVTDNPGATAHM
SSLAGCSIVRNKGIDPIFQVTCRDRNRLAIQSDLMGASALGVNNVLTLAGDPVKNGDQPD
AKAVFDINSKKILSIMQSMNDLGETMSGRELQTKSNFFPGGAAIIHEPENNWNPVALKDK
VDHGAKFIQTQFCYDVDLLREYMKHIVDSGLSEKLFFIIGIGPLRSDKSAKWMRDRLFGT
VIPESIXQRMEQSENQIEEGVXICAELINQFEEIDGVHGAHLMAPRNLSAIAPTVKQAGI
KI
>A0A259SIN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. 13-71-7|TrEMBL
MSFDAPPFAPAGAVVPRVPISFELYPPRTTAPIEALHETIQQLASAAPRFISVTYGAGGS
VGGRSLDVLRYIREHTAVEPLAHLTCVGNTYAGASRLIREFLDAGILSFLALRGDPPLDE
SQPFLGDLESSAQLVQLIDRAQAERAPYQERPIPGVPGAVQVTPRRKVNIAVAAYPNGHP
RSTYRNQDIDALLAKQAAGATLAITQLFFHPDDYFAFVERARRAGVTIPILPGIMPITSP
ARLRRVLELSGEELPAELSIDLEVEPTVEGRTEIGVAHAAELVRELVDGGAPGIHLYAFN
QHRTVLDVLTAAGVLPEGSAASPTDGALQFAETSGAH
>A0A661JNF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MASRFKEALESGKFVVTAEVGPPKGTNIEKLLYHIDLLKDRVDALNVTDNQSAVMRVCSL
AVCKLIKDRGGEPILQITCRDKNRLAIQSELLGAHVLGIHNVLCLTGDHIVVGGHIDAMP
VFDIDSVHLIQAVRTLEQGKDMAGNELDGPVSFCVGATVTPEADPLEPQLLKFRKKVRAG
IDFVQTQAVYDLDKFRRFMEFARKFDRVKILAGIVLLASVGMARYMNANVPGIFVPEEMI
RELASAPKGKAIEKGIEIAARLIRTIRDERICDGVHIMAIGREERVLDILDAAGM
>A0A352RJW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MHLIELYKKKDFVFSIEIFPPKTAKGMEKLKTTLEAFKSCTPDYFSVTYGAGGTSRENTH
ELAAHIHHDLDVPAMAHLTCVAHTVEEIDVVLSNLKNSEITNVMALRGDPTAGTKHFVQP
KGGYHYASELITAIREHSDFGIGAAGYPEGHLENPDKDDDRKHLHEKIAAGAEFIVTQFF
LENTHFLRWRDQLRREGASVPLVAGILPPANWKATKHMSEMCGVSIPEDLAQALIKNETD
PEASREIGFDHVENQFEELLQEGVEGVHLYALNRLSTVERLGPILKDASGTISTPHL
>A0A414PAF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ruminococcus] lactaris|TrEMBL
MKIIDRLNEDRINISFEVFPPKTDAGFANVQRATDEIAKLDPSYISVTYGAGGGTSKNTA
KIASHIKDDLHVLSLAHLTCASSTKEEVREVIRNLKELGIENILALRGDIPEGMKFPDGD
RFHYAYELVEEIRKQGDFCIGAACYPEGHVENEHKEDDIRFLKQKVDCGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLALLDRFGSSPE
AMMQAGIAYATDQIIDLLANGVKNIHIYSMNKPEVAAKIMSNISEIIKC
>A0A1H5RHQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis pretoriensis|TrEMBL
MTSVSPRRAGTSPAAAPAPRTVRDRLAAGTPVLSLEFMPPRPADDAGRIWQNVRKLESLH
PGFVSVTYGAGGSTRDNTIAVAARIARETTMLPVVHLTAVDHSVRELRSFVGALADAGVV
DVLALRGDPPGDVTGEWVRHPEGLEYASELVTLLREHGDFCVGVAAFPFGHPRSGSVAED
TAHFVAKCRAGADYAITQMVFDADDYLRLRDRVTAAGCETPIIPAVMPVTTMKTIARSEQ
LSGAPFPPRLAERFAAVADDPAAVRALGIEQATLLARRLLAEGVPGLHFITFNFARATTE
VVAQLPVFP
>A0A2E9GMY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIADRYGENRPVFSFEFFPPKTDKGFQNLYATVRELKRLNPDFVSVTWGAGGSTRARTV
ESTLQIQQEIGVTAMAHLSCIGSTPDELVETLERLEAGGIQNILALGGDRPEGYVAPAGS
FTYASELAEFIRGRWGFCLGGACYPETHPAAASPEADLENLKHKVAGGVEFLITQLFFDN
ADYFEFVTRARAAGIGLPIVPGIMPVLNVRSVRRMTTLSGGRIPDELQAALTRVEGDDDA
TRDVGIEWATLQCRELLERGAPGIHFYTLNRSRATRAIFQHLLER
>A0A661T3V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSLAEKIESGKFIVLGEFEPPKGADFSPLLENADRVKGRLDALVIPEMANAVMKASSLGG
CAFLQQHGFETVFQVCCRDRNRLALQADILSAGALGVPNIMAVPGEDIRFGDHPQARDVF
DLDLIQLLEVLRNFSAGKDMAGVELAGAPRFCPGSSIAAGAMGGALDIELKNLEKMIGTG
VRFVITSPVFDLHLFSQFIKRVDMKKVAVIPTVLLLKSAGMARYIDRNIKGISVPKEIIR
DIQKSPDKAGECIRIAADLISRFREMGMAGVMISTVGWEDRLPRILDAAGL
>A0A661QMU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTFREKLEQKKFAVLAEFEPPKGADFSEMLTNAINVKGRIDAFVVPEMATAVMKASSLGG
CLSLQINGLETVFQVCCRDRNRLALQADILSAAALGIPNLMVVKGDDITVGDHPQARAVN
DIDVFQLLEVVEQMRNGKDMAGIELKGAPDFFVGALFNAGAQGGLFDLELEELEKKINLG
VKFVITNPVFDLKILERVLKRLDKDQVALIPKVLLLKSAGMARYIN
>A0A534NXD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKITDMLRFAAERGEPVFSFEFFPPKNDAGVSGLFETLRALRPLAPSFVSVTWGAGGSSR
GRTLEMVTRIKRETEIEAMAHLTCVGASRKELEEQLAVICDAGITNVLALRGDPPRGQRE
FIVHPEGLAHANDLVKLARDVANARGVDLCVGGACYPEGHPETRDLSQDLRHCKLKVEAG
ADFLITQLFFDNRRYFEFVGRARAAGIDVPILPGLMPVTNVDQIERFTALCGARIPAGLS
AALRARRDEPDAALQLGVAYAALQSADLLRSGAPGVHFYTLNRSTATRAILAALRAQEPW
REG
>A0A1J0WIZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter alexandrii|TrEMBL
MATPNVSFEVFPPRTVDAAFKLWDSAQALAPLAPRFFSVTYGAGGTTRDLTHDAAHVLRR
TSGLPVAAHLTCVGASRAETLEVAESFAKIGVTDIVALRGDPQGEDTRFTPHPEGFRDSC
ELISALAETGKFTIRVGAYPDPHPESASPEANIEWLKRKFDAGADEAITQFFFEAETFLR
FRDACVKAGIEKPITPGILPIVNWKSARNFANKCGTPVPAWVDDAFTKADRDDRSALLAT
SLCTELCSELVDEGVENLHFYTLNRAELTRDVCRALGVTPQVTLEDVA
>B3LHI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain RM11-1a)|TrEMBL
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRD
AENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDVKLDLEYLKQKID
AGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQH
FSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL
PMESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANKCLELWSTPTSINDVAFLVINYLNGNLKCLPWSDIPIN
DEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL
>A0A496YHY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSETKTPSKLEKILSLGHLAVTSECGPPRGSDPEVIRKKAEMIKDYVDAINITDNQTSVT
RLCSLASCIHLKLMGLEPILQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQKFGDN
PQGQNVFDIDSMQLIQMVRLMRDEGKFLGGDQIQRPPKMFVGAAANPFADPFEIRVPRLA
KKIAAGAEFIQTQCIYNLDKFELWLKQARDRGLHEKVYILAGLTPLKSAGMAKYMKNRVP
GMDVPDEVVKRMSGVPKEKQPEEGIKICVESIERLKEVEGVSGFHIMAIEWEEKVPEIVE
RSGLYPRPKLDD
>A0A432HRY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MIRPGSFTITIEVVPPEGTDCQPLLTELSGLAHLKFDGFSVATNPLAKPCMSAMVVCSLI
QQQIGKPAILHCTPRDHNRLGIFSLLSGARAMGIDNVLVATGDFVALKDRENTRAVYDMN
VFELVKKARELGLKTGVVLDPNPGSPGFKTAVKRLEQKAEAGAQFIVTQPVYDMAGVEQL
ADATRHLGIPLVMGILPLRTAGHAEFLHHRVSGISVPRRVRERMARADDSVAEGVANARE
MLSAARDFFAGVCIMPPFNHYEVMTEIVAPAAR
>A0A1J0EDD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia rettgeri|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSEEMEQTLWKSIDRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKDKTGLIAAPHLTCIDASRDELKGIARDYWNNGIRHIVALRGD
LPDNSNKPDMYATDLVELLKGEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPAWMSKMYE
GLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A661N2U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIADLYAAEGGPVLSLEFFTPKNDAGRKALFRAVERLATIEPGFVSITCGAAGTTRERT
ADLAIEMQDQFQLTAMAHLVCTGTTQLELGETLRHMQARGIDNILALRGDPPKGATDWTA
VEGGFRHADELAAFVSERFSLGIGGACYPEKHHEAKSLEADIDNLARKVDAGVEFLITQL
FFDNDKYWSFVDSVRARGIEVPIVPGIMPVLNLANLERIASLSPGTTIPPELETAFREAG
EDDEVALQAGVRFAAQQCRALLAKGAPGIHFYTLNRSKATLQTVAQL
>A0A661KFP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKAGSNLEKILEKGEFAVTGELGPPKGNDIEVIKKKAEHLRGNVDAINVTDNQTAVVRMS
SIATCALLVQMGLEPVMQMVTRDRNRIAIQSDIFGATALGIKNMLCLSGDHQIFGNQKEA
ANVFDIDSIQLIQCVKAMRDEGTLLGGQEKIEGQVRLFIGAAANPFADPFEFRVVRLAKK
VKAGVDFIQTQCIYDMDRFKEWMRMVTDRGLHEKVHILAGITPLKSGGMARYMAKNVAGI
TIPDKIIARMVKAKDAREEGMKICVEQIEELRQIKGVHGIHIMAIEWEEVVPEIVKRAGL
LPRPKVSKN
>A0A1Q7Z6J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium 13_1_20CM_2_69_21|TrEMBL
MRITDMLRFAAERGEPVFSFEFFPPRNDAGVAALFETLRALRPLAPSFVSVTWGAGGSSR
GRTLEMVTRIKRETEIEAMAHLTCVGASRKELEEQLAVICDAGITNVLALRGDPPRGQRE
FIVHPEGLAHATDLVQLAREVADKRGVSLCIGGACYPEGHPETRDLAKDLRHCKQKVEAG
ADFLITQLFFDNRRYFEFLGRARAAGIDVPILPGIMPITNVDQIERFTALCGAHIPAGLS
AALRARRDDPDAALQLGVAYAALQCAYLLRGGAPGAHFYTLNRSTATRAILAALRAQEPW
RDA
>A0A2E5PQA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MQDFDKYIEQDFIQKIIQLSNRCMSDKIPNWSLEILPHHVSEVQGLPQWVEEIYVTMIPG
SXISEVVEASAQLVDEGRTPIPHIAARGMESREQFSEMLESLKQKGVNRLLLIGGGEEEQ
QGPFTEVMDLMETGELQRIGFEEIGIAGHPEGNPSDPDAXNSLXKKTRWAXXQGISTRXV
TQWCFESQTLNRWINNLHEQGVTNPIHIGIPGPATLKTLLRYAQVCGVKASSEVLKKQGF
NLGKLLFVNKPDRLVQEIRGHQQLHLFPFGGLTKSSEWLQQXRNLASTA
>A0A661JTK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MAFKEALESGKFTVTAEVGPLKGTDTTEIEEVAELLKGKVDGVNVTDQQSAVMRLGSLAT
CHLLVEKGLDPIFQMTCRDRNRIALQSDLLNAHVLGIRNVLAITGDYPTLGDHPDAKAVY
DLDSVQLVWTIRRMNEGYDLAGNELEGKTDFFVGAVVTPVTDTDAAFELQLIKMEKKVEA
GARFFQTQAVYDVDAFARFMKRAEEFGVPILAGIIPLKSVGMARYMNKNVAGVFVPEHLI
EEMAKAEEKARKGLEIAARLIKDLQDLCQGVHIMAIGWEKKVPETLALAGLVQ
>A0A3N5Z926|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRVVEAIEKSKKPLFTFEILPPVKGSDIHSIYRAIDPLMEFEPSFIEVTYHREEISYKEL
PDGNIEKKVLRKRPGTVGISAAIKYKYKIEVVPHIICGGFNREETENGLIDLHFLEIYNL
LAIRGDNLPGEKFFKPEKGGNQYTLDLIRQIRELNQGIYQDKELVNNAPTNFSVGVAGYP
EKHAEAPNMKTDIKHLKEKIDAGGEYIVTQMFFDNRFYFDFVRQCREAGIKVPIIPGLKP
ISTIGQLNTLPRTFNISIPEELQKEVEKCKDNRGARQVGIEWCKMQSKELMNTNVPALHY
FTMGKSDNIKEIVREVL
>A0A661LRK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSFQKKLLAGDFVVLAEFDPPKGVDVSDLFSNIIRVKGRVDGVIVPEMAQAVMRMSALGG
AALMQQNGMETVMQICSRDRNRLALQGDILAAYMLGVKNLLVVPGDEIMYGDHIDATPIS
DIDELTLLRAIKGLEKGADMAGMELKGSPKFLTGCSIRGAKNEMAMEAELELAQRKVNEG
AQFVITPPVFNIPAFTYFMDKAKALGVPIIATVFLLKSVGVAQYISTNVPGPPIPDEMMA
RIRKAPDRIAECLTIAGELIIALKDLCQGVQVVTMGWENRLPAILDAAHV
>A0A661IJL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MAFKEALESGKFTVTAEVGPLKGTDTTEIEEVAELLKGKVDGVNVTDQQSAVMRLGSLAT
CHLLVEKGLDPIFQMTCRDRNRIALQSDLLNAHVLGIRNVLAITGDYPTLGDHPDAKAVY
DLDSVQLVWTIRRMNEGYDLAGNELEGKTDFFVGAVVTPVTDTDAAFELQLIKMEKKVEA
GARFFQTQAVYDVDAFARFMKRAEEFGVPILAGIIPLKSVGMARYMNKNVAGVFVPEHLI
EEMAKAEEKARKGLEIAARLIKDLQDLCQGVHIMAIGWEKKVPEILALAGLVQ
>A0A661L6S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
VNITDNQTAVVRMSSLAASAIMVGENLEPNYQLVCRDRNRLAIMSDILGAYSLGIRNMLC
LSGDHQKFGDHPNAKGVFDIDSIQLLGMVKRMRDEGRFLSGAEIEDPPRLFIGAASNPFA
EPFEWRVHRLAKKIEAGADFIQTQCIYNMDKFREFMKRVVDMGLHEKCYILAGVTPMKSV
GMARYMAKQVPGMDVPESLIKRLKGAGKGKAAEEGIKFAVEQIQEFKEMEGVAGVHLMAI
EWEHRVPEIAEMAGMLPRPTV
>A0A661R5Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSFQTKLSSGEFAVLAEMNTPKGIDISDLITNVRYLKSRVDAIVIPDMDNGVMHMSALGG
GALMRQQGVEPLIHVYGRDRNRMALQGDLLAAHVLGIHNLLVVQGEDMANGDHQDATVVN
DLDETALLQMIGSLTQGTDMAGFELKGIPKFTIGCAIAPIADDAQLKREVDAAQKKIDAG
AQYILLPPVFDT
>A0A645GG53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MESGAEYFLSQPVFTERAVENLALAKKELGVRLLVGILPLASLKNALFLNNEVSGISIPP
GLIDRLRDKDAQEVREISLEFCMDVVQRTKPFCDGYYIVTPLKKVDLAAGLVQRIRSQNP
>A0A645GPF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MREKAEAGARFFITQPVFSLDPLDRVLAVANELGVPLFAGIWPLASYRNAEFMRNEVPGV
VVPDEIMRRMEAASTREEQYACGIAIARETVAELRGRVAGVQVSAPFGRVESVFAVFENQ
>A0A645D4H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MTRISVELVTRDEEFLAAELSALKDQFPVDTINIPDLLRFDIRSWTGCGLVRQVGKKAIP
HIRDIDIDVRKPLPMSRYLVDNKITEVLVLTGDRPQDMGHKIYPSTSVDVIRKIKHELPG
VKVYAAIDQYRSSIRNEIDYAMRKLYAGADGFFTQPFYDLRFMEIYAEQLQATEVFWGIS
PVISENSVNYWEVKNNVVFPGEFRPTLEWNITFAKQALEFVNKINSNIYFMPIRMKSADY
LAGIFNL
>A0A5Q4D7R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MGTVLYERGIFLNVCYDELSRSDPELVAAVHRAYVEAGAELVETNTFGANPVKLSAFGLD
ADTEAINRAGASVARSAAGSRARVLGAMGPLGIRIEPWGPTGADEARDFFGRQVDGLLGR
GGADGPDRGAGPYGVEGVAGANAVDGFILETFQDPAELRQALEAIRARCDLPVLAQVTLA
EGGRTAYGADVETLVRELEDWGVDAVGFNCSVGPAGILEAVERAAEATGLPILAQPNAGF
PRTVGDRKMYLASPEYMARYARRMVDAGARFVGGCCGTTPEHVRCMGEALAETDRTRDTT
RSGPRQAAPAQHQQPARTVPEPPASPALPLGERSRLGAALQSGDFVSLVEVVPPRGWDPE
ALLAQGLALRDAGVTAVTIPDAPRGLARMGSLPAATLLARDTGVEVLAHYACRDRNMIGM
ISDLLGAAASGVRNILLVTGDLSPTGPYPDHTTIFDIDSIGLTNVVRRLNEGHDPGGHPV
EPPTRFVIGVTLNQGAVDREREDRRFRFKVEAGAEYAVTQPVFDPGTLLGFLDRHAGHAA
RFPVIAGIWPLTSLGNAEFLANEVPGVVVPAGVVERMRAAERRGPEAATEEGIRIAVENV
EAVRHRVRGIHVAAPRGRIDLALAVLARAGLQGAPA
>A0A089I383|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL H7-0357|TrEMBL
MKPDLRSAWNTNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPGVIEDVHRSYIEAGAVL
LESNTFSANYDRLSKYGLESKVGEINRAGVRIARQAAGEAGYVVGAVGSIRAGKRANLSS
SELKRYFTEQITALLEEQPDGIMLETFYDVEELHLALRTVRKLSGLPVICQLAVDETART
LDGLTLPEAFRILEQDGADVIGFNCRTGPNGIKRALKTLQGSLTLPASVYPNAGVADYVD
GQYRYGATPDYFGQMAPVFAGLGSRIIGGCCGTTPQHIAEISAALRDYAPQPLPEPTQKK
STERIVVQEHLGEDEGRSGGEPTLVDLVKERHTVIVELDPPRDLDIAKFMRGADALRRAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHVACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIARIAKATEHLDIPIFLGIMPLASGR
NAEYLHNEVPGIQLSAEVRSRMQGLEGEVGRAEGVAIAKELLDAATEHFNGIYLMTPFMF
YEMSVQLLEYIWEKQGRKLSPLFR
>A0A1X0RW19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus microsporus|TrEMBL
MKIIEKIEQAQKNNKINYSFEYFPPKTELGYANLIDRIERMAKLGPEFISCTWGAGGSTH
ERTLELCSTTQSVYGLDTCMHLTCTNMEKDKIDIALKQAKEAGIQNILALRGDPPRGHEY
WTPIDNQFTHAIDLVKYIRQQYGDTFCIGVAGYPEGHVDSPNKEQDMQYLKEKVDAGADF
IVTQFFYDPEAFINWMQNIRHIGITVPVVPCIMPIPTYQSFRRMIHLCNVKVPTEVMKDL
DEIKSDDQKVKDYGVRLAVNIINELHKRANICNFHISTLNLERSTRLILEQLGLIHHTEK
LTANKPSPWAPVHDPIKVEMWDEFPNGRYGDSRSPAYGENTYSLNQILPTSQAILKWGQP
QSEEDVRQLFKRYIQGELDSLPWCEESPQTETGTICQQLIHLIEQGYLTISSQPAVNGAP
SDDKVYGWGPKGGYVYQKAFIEFFISDQAVSELLARLSKDPSVTFYAANRKGDFVTNVTD
PDAQNAVTWGVFPSKEIIQPTIIEKASFESWKVNNQ
>A0A2J0TF18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSGAIGRLRPPPNGPADRAQRAQAFVSAVSLEVSAKAMPALRAEAARIAPGTAISIPYLP
SEDDAARLAAARTVRELGFEPMPHLTARRIGSRAALEHFIDRAVIDAGVERCLVIAGDLA
TPAGPFADSTSIIESGVLERAHIKVVAVGGHPQGHPVMTSADRWRVLERKCQLIEARSMK
PLIITQFAFDADSVLTWLTELRGRGITPPVLAGVPGPASIARLVRYAAMCGVSASTSMLS
RYGISIGRLLGRAGPDVFVDRLVDGLTEAHGQVSPHLFPFGGIAQSMEWVEDYRMQAGTL
MAQGGRRPPHPPSQG
>A0A285STE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AR29|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIREVAKQIY
>Q2IZ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas palustris (strain HaA2)|TrEMBL
MTDVLQHIPAISFEFFPPKTDEMERNLWQAISRLAPLHPRFVSVTYGAGGSTRERTHSTI
ARILRETSLTPAAHLTCVDAPCADVDDVVERYHEIGVRHIVALRGDPTSGLGGAYTPHPQ
GYRSSADLVASIKRKHPDIDVTVSAYPEKHPESASFDADLDMLQAKVDAGATRAITQFFF
DNDLYFRYLDRVRARGIDIPIVPGILPVQNFKQASSFATRAGATVPDWLAKQFEGLDDDP
DTRKLVAATMAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGLRPQAAQKAA
>A0A5C5UQS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium canis|TrEMBL
MTPTNYQLAISDALKRPTPGRIPFSVEFMPPRDDAAEARLKHAAKTFHDLGASFVSVTYG
AGGSTRERTARVARRLARQPLTTLVHLTLVDHTREELVDILREYARLGLSNLLALRGDPP
GDPLGEWIPTAGGLTYASELIELVQSLPECEHFEIGIASFPEGHYRAASLEEDTHYTLAK
LRAGANYSITQMFFDVEHYLRLRDRLAVDAEHGHKPIIPGLMPITSLRSVRRQMELSGAA
LPPALERRLERAAAGDEEANREAIREVGIEVTTEMAERLIAEGAPDLHFMTLNLVRATQE
VLHNLGMAPAADMDVIR
>A0A1H3B2N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allochromatium warmingii|TrEMBL
MTHVYSVELFPPKTAEGMNKLKQDIPQINALGPAYFSVTYGAGGSTREGTFETVAWLRSQ
GIDTAPHLACIGSTREQVREILAQYHAQGINRLVALRGDLPSGMGAGNSGDFRYANELVS
FVRAEFGDAFSIEVAAYPEYHPQAGNPARDLENFKRKVDAGADAAITQYFYNADAYFGFV
ESCERVGLSIPIVPGIMPITNYTQLARFSDTCGAEIPRWIRRRLEGYGDDVASLRAFGHE
VVLGLCQRLIADGAPGLHFYTMNQSGPVTCLWRDLGLTI
>A0A5J6Z9C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium urogenitale|TrEMBL
MPPRDDAAEQRLWGAAEAFHDLGVSFVSVTYGAGGSTRERTLRVARQLATKPLTTLVHMT
LVDHTVEEIKQLIRSFASYGLTNLLALRGDPPGDPNAEWIPTEGGLLYTNELIELAKSMP
ECEDFDIGIASFPEGHYRAKDLESDTYYTLQKLRAGAEYSITQMFFDVDHYLRLRDRLVA
ADPEHGAKPIIPGLMPITSLRGVRRQMELAGASLPKSLEKRLLDAAAGDEIANKEAIREV
GIEVTTEMAERLIAEGAPDLHFMTMNNVRATQEVLHNLGMAPAWGPGYGHDMVR
>A0A259PF51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomonas sp. 14-66-4|TrEMBL
MHTVKEIAEEGVAAAPHLSCIGASADSIRNLLRRYRAEGIRRIVALRGDLPSGYGIGGEF
HHARDLVAFIRAETGDWFHIEVAAYPETHPQARTPQDDLRHFAEKMRAGANSAITQYFFN
SDAYFRFVDEATAIGVDAPVVPGIMPITNASQLLRFSEVCGAEVPRWIRLRLQSFGDDRA
SILAFGREVVADLCDQLLAGGAPGLHVYTLNQAAPTLDLLRDLGGR
>A0A0M0P7Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAARLKDYSPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIEFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLVEGGAPGLHFYTLNLAKPTTSVLQLLHG
>A0A2P2E7R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Phycosocius bacilliformis|TrEMBL
MTQPIISFEFFPPKSEAMEARLWDAVSRLSPLQPDFVSVTYGAGGSTRERTHRTVKRIID
ETNLKPAAHLTCVAASRSEVDEVLQSYWDAGVRHIVALRGDPPTGVGTEFVAHPDGYINA
TEVTAAARRIGDFDVSVSFYPEKHPESPSLAHDIDVLKAKIDAGATRAISQFFCEPGVYL
RFRDAAAKAGVTIPLLPGIMAVGNVAGYMRMAHSTGTSVPAWFAEAFDGLDQNPEVRDMV
AASVAADLCLKLQAEGVDRFHFYTLNRAELALATCRRLGLKTPIIERDVA
>A0A428FKA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQILDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1D1XD90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anthurium amnicola|TrEMBL
MKVIEKMRAAVEGEGRTVFSFEYFPPKTEDGVENLFERMDRMVSHNPSFCDITWGAGGST
ADLTLDIANRMQNMICVETMMHLTCTNMPVEKIDHALHTIKSNGIQNVLALRGDPPHGQD
KFVQVADGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDMIKGEGGATFEDYQSDLVYL
KKKVDAGADLIITQLFYDTDNFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPSEITAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKTALSILMN
LGLIEESKVSRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPRGRWGDSCN
PSYGALTDHQFMRPRSLGKKLQEEWAIPVKSVEEINERFMSYCLGKLTSSPWSELDGLQP
ETKIIDEQLGQINLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFCPKDKL
DVLVEKCKAIPSLTYIAVNKDGQCVSNVGPTSVNAVTWGVFPAKEIVQPTVVDPASFMIW
KDEAFEIWTRGWACLFPEGDPSKDLLEQVQRTYFLVSLVDNDYINGDLFAVFKDI
>A0A7X9U6C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas arctica|TrEMBL
MALSLKEKIEDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQARPFAFKQTVDPREYSHLLRDLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDL
QNVVLVGSPSSVGDIKLSLPDAYKALAEQSDDFFLGGVTIAERHSSKQNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGITPQRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKLIA
>A0A081L6W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus zhangzhouensis|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSIDEIKR
SFREQLYILLNEQPDGLLLETYYDMEEAKSVLEIARKETTLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPILENSYLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHISAMAEAVIDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKSAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIREIMAKAGEDKEKQRTEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKEPNVNVNYH
>A0A7Y2E1Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermales bacterium|TrEMBL
MKVAELLANAESPQVSFEIIPPKRGGSVAEILEIVEGLMKFDPPFIDVTSHSAQVYYEEQ
PDGSWRRHVKRKRPGTLGLCAAIKGRFNVETVPHLLCKGFTREETEDALIELNYLGIQNV
MALRGDDNGFRKPETPSKTRNKYAIDLVRQISEMNRGSYLEDLIDAAPTNFCVGVAGYPE
KHFEAPNITWDILNLKRKVDAGADYIATQMFFDNKPFLEFVERCRDVGIDVPIVPGLKVI
TRKSHLQTLPSRFHMQIPEALAAEIEEADDRHVADIGVEWAIRQSTELLEAGIPYLHFYV
IQTPEHAVRVVDSLRKMA
>A0A3A8YKL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium 1xD42-67|TrEMBL
MKLCDLFGQGRTIFSCEVFPPKKTAPVDSIYRTLDGLKDIRPDFISVTFGAGGSQGDKTT
RDIASLIQNQYHIPAMAHLTCVAAGREDVDRLLDQLEADGVENILALRGDVRPDVPSKTD
FRYASELAAHIRARGGFGVSAACYPEGHLESPDLVSDIRHLKEKVDAGAQHLVSQLFFDN
EDFFRFLERARIAGIDVPIEAGIMPVLSKSSIQRMVSMCGASLPARLTRILARYGDHPEA
LREAGIAYAIDQISDLIAGGVDGIHLYTMNDPEVAKQIAGSIASIRTV
>A0A3A5WM04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AF34-31BH|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A2Z6E310|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aerosticca soli|TrEMBL
MSQRVAEVASALVYLSMRKRRYTIAAFVETAMPSLSFEFFPPKTAQQREQLDQTVTKLAA
FGPDYVSVTFGAGGSTLNYTRETLAHLKHMHGLEVAPHLSCMGGTREEIAALLDDYRAAG
YRRLVALRGDLPSGMASPGDFRYAAELVRFVRERTGDHFRIEVAAYPETHPQAADALVDL
EHFRAKIAAGADGAITQYFYNPDAYFRFVADVRRLGVSVPIVPGIMPIANFSQLTRFSAS
CGAEIPRWIAKRMQALGDDAQAIRELGAELVAQLCRQLLEGGAPGLHFYTLNRARPTMAV
LERLR
>Q5E2E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliivibrio fischeri (strain ATCC 700601 / ES114)|TrEMBL
MAYSHASHLESLNQNIAELDGNINVSFEFFPPSSEKMEETLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLIAAPHLTCIDASRSELIDIANDYWANGIKDIVALRGD
IPPGGGAPEMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQASRFAKMNNVKIPGWMAQQFE
GLDDDPVTRQMVGASHAIDMTRILSREGVKDFHFYTLNRAEHTYALCHTLGVRPK
>A0A3P1WLN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus sp. OH4464_COT-324|TrEMBL
MLSPAGLTVAELLSQGKPLFSFEFFPPRTAEEVPRLLNTVAALAPLAPDFVSITYGANGS
RRDRTMEATREIARIGNPMTVGHLTCVDQSKSDVANALALYREVGVRNILAVRGDMPGGG
RWRPHPDGLRNATELVEFVKSEGDFCVGVAAFVSPHPETNDADLDARILLDKVAAGADYA
ITQLFFDTADYFALVNRMQSLGCGIPIIAGLMPLTAIRQIERFEALSGAPLPADFVAGLR
AADPADVRSIGISHAKDMCRILLDGGAPGLQFFTQNRAKATREVLAAVRGQRN
>A0A436D014|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.006.04.2.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A2AXF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cinnamonensis|TrEMBL
MTVLRDLIHQAAPTFSFEFFPPKTPAAATALWRTIRRIETLAPAFVSVTYGAGGSSRERT
VEVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLAVRGDPPGDPGADWI
PHPQGLTHAHELVRLVKESGHFSVGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQ
MFFHTEDYLRLRDKVAAAGCDTPIIPEIMPATDVRQISRFARLSGAAFPEALAHRLEAAR
DNPAEGHRIGVEHATAMAQRLLAEGAPGLHYITLNRSTATLEIHRNVTNSRSTPHDLAAH
H
>A0A7V1H3C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MENKFREKLESGQFVITAEIGPPKGTDIREMIEHIKLLADKVDALNVTDNQSSVMKYPSL
GGCIEIMKAGGMPLLQMTCRDRNRLALESDLLLASRLGIQNILALTGDAVTVGDHPQAKP
VFDIESVQLIDVINHLGEGVDIGDNKLEGDPQFFPQFYTGAIVTPEAEPIEPQLIKFEKK
VSIGAKFFQTQAIYDLEKFKKFMDYARKFDVKIMAGIVLLVGPGMAKYMNKNVPGIIVPQ
YLIDELVDAGKGNGLEKGIEIAGRMIREIKQNKLADGVHIMAIGKEAMVPSILKTAGLA
>A0A7K3KT31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Z1|TrEMBL
MRVIDHLQANPGRTAFSFEILPPLKGNSIEKVYNIIDKLRDFDPKYINITSHHSEMIFKE
MPDGSFRPQKMRKRPGSVAIASAIQNKYGITAVPHIICKGFTRDETEYALIDLNFLGVHD
LLLLRGDIKGPEKSDDPTKINRHATDLQAQVNDFNRGIYADGETFEPNATPFSYGMACYP
EKHEEAPNMDSDLYYAKQKVDGGADYLVTQMFFDNSKYFDFVERCRKAGITVPIVPGIKP
VVFANQLNVLPRVFRSDIPEAFASELRKCKDDAEVREVGIEWCIGQCRDLIAHGVPSIHF
YTLMASESVRRIAKEIY
>A0A496RBQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MKKPYLERVKKGVLLFDGAMGTMLYDKGVFINRCFEHVNITDPDKVLEIHRDMAAAGAQV
LTTNTFGANPIKLKSFDLDDKTVEINRAGVQLAKKIAGEDLYVAGSVGPTGVRMAPVGHI
SSEVIAEAFRIQITALLEEEVDLLLFETFSNADELILAVRTARSISNTIPVQAQVTIRTN
DAEDAEDRYIRLFNRLEKEEGIDILGLNCSTGPAAMLDILHSIQNHVTKPISIMPNAGFP
RDVEGRQLYLASPDYFAEYSLKFLDSGASIIGGCCGTTPQHIEKMGKAIISLDRSRRREL
DIELSESRSFDPVPLEKRSLMGKSLCEGSWITSIELVPPVGIRLEKTVARASLLKKEGIT
AINIPDGPRASSRISALLTSIEIQRSTGIEAIPHICCRDKNLIGLQSELLSAQAAGLHNV
LIITGDPPKTGNFPDVTGVFDVDSIGLISLASRLNRGIDLAGNILPEPTSLVIGAGANPA
AQFPEREIERTFQKAEAGADFFITQPVFDIQLLVGFLEKIKDAGVPVIAGVWPLASHRNA
LFLNNEVPGVTIPDHILKRMEKHTGKEAAREEGIAIAKTIIEEIRPLIAGVQVSPPFGRV
ETALSVIR
>A0A7C4N7J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MDIVTRLQQKQPLLSFEVFPPKTLNGEENLFHELSVMVGFKPDFISVTYGAGGSTREKTL
EIATRIKSTFSIEPLIHFTCVGQSRHDIASYLNHVRSLGFNNILALRGDPPAGQHQFTPH
PEGFKYANELVEFIRTMDHFTIGVAGYPEGHIEAPDLDTDISNLKRKVDAGADFIITQLF
FNNDKFYIFMEKTAKAGITIPIIPGIMPLTNMAQLQKVTTMCNPDMPAPLLREIEKCILP
DDICKVGIEFTINQCKELQSYGVPGFHFYPLNKSTAVKSILDAFWH
>F6TEC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ornithorhynchus anatinus|TrEMBL
MVNEAASSGSRRSSSSSSGSEGSKDSSRCSTPGTDAERHERLRDKMRRRMDSGDKWFSLE
FFPPRTAQGAVNLISRFDQMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVDYCGLE
TVLHMTCCHQTRDEITRHLHKAKRLGLKNIMALRGDPIGDEWEEEEGGFNHAVDLVKHIR
SEFGDYFDVCVAGYPKGHPEAESFEADLQHLKEKVVAGADFIITQLFFQAETFIRFTKAC
AAVGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEITAVIEPIKDNDAAIRNYGIELAV
TMCRELLVSGVVSGLHFYTLNREVATVEVLKRLGIWNEDPRRPLPWAVSAHPKRRVEDVR
PIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKNYYLFCLKSKSPREELLKMWGQ
ELTSEESVFEVFAYYLSGEPNQNGYKVTCLPWNDEPLAAETSLLKEELQKVNRRGILTIN
SQPNINGKPSADPVVGWGPSGGYVFQKAYLEFFTSSETVAALLKVLKKYELRVNYHIVNV
KGENITNAPDMQPNAVTWGIFPGREIIQPTVVDPVSFMSWKDEAFALWIEQWGKLYEEES
PSRMIIQYIHDNYHLVNLVDNEFPLDNCLWQVVEDTFKLLNEPARQ
>A0A7Y8BVB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas gingeri|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLEQYKGAGIQRIVALRGDLPSGMGMASGELLHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEADLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQAFG
EQVISQMCDRLLEGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7C3TMS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MDIVNRLQQKHPLLSFEVFPPKTLNGEENLFHELSVMVGFKPDFISVTYGAGGSTREKTL
EIATRIKSTFSIEPLIHFTCVGQSRHDIAIYLNHVKSLGFNNILALRGDPPAGQHQFTPH
PEGFKYANELVEFIRTMDHFTIGVAGYPEGHIEAPDLDTDITNLKRKVDAGADFIITQLF
FNNDKFYTFMDKTAKAGITIPIIPGIMPLTNMAQLQKITTMCNPDMPAPLLREIEKCTLP
DDICKVGIEFTINQCKELQSYGVPGFHFYPLNKSAAVKSILDEFWH
>A0A7R9R6H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon GB37|TrEMBL
MNFRKKIETGKFVVTTEVAPPRGTDTTILREELDLIPRSVDAVNLPDNQRSIMRMSPIGA
VHLLHEKGCEVILHITCRDRNRLALQSDLLGAWSIGVKNILAMTGDHPLIGDTVGAKPVY
DLDSTQLLQLIQNLNRGRDIMNRQLEGGTDFIAGAVVRPDPDDKMQLLKLEKKVSCGARF
IQTQPVYKTEEFKKFLKKASHLKTHIIAGILPIFSLKTVKFIDEKLPGTTIPEEVKQRIK
NSTDPANEGIEIAAEIIRELQSVAGGVHIMPITTHRYTEAILRRADLL
>A0A660TEC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MNIENSIKRFHVEVLPPKQNAENLEERLEKFADRYTRVVEEDYCACITDNAMGHLSFQGT
ELIEELELPVKPENVMIHLNTFHTKKDLDNILNSCAERGIKYILAVTGDGSPRLPKLRPL
DLGINGLESVTSVELLNYIKNEYPGYFTLGVAFNPYEPEQHEFNKMRRKINAGAEFAITQ
PVVEQNEAVEKMLKEFDIPVVVEAWMSRKLHLLSECVGYEIPENTEYDPVANLEKLMKNY
PDCGVYLALLNYKRQFPLLKEMRSYAGR
>A0A2W5NPW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium pentaromativorans|TrEMBL
MTSAERPVSAPLFEDLPGDISVSFEFFPPKTEKMEEQLWDAITQLAPLAPSFVSVTYGAG
GSTRERTHSTVSRLVRETDLVPAAHLTCVGASKDEIAEIADQYWEAGVRHIVALRGDPPP
AHGGIFTPHPEGYTGAADLVSGLKARHDFDISVAAYPEIHPEALSADADLDNLKRKLDAG
ANRAITQFFFSTDAYFRFLDKALAAGITAPILPGIMPVTSFAAIRRMSGNTEIPGWLERM
FEGLDDRPGPRALVAAVAAADLCRRLYQGGVRDFHFYTLNRAEQAYAICQLLGLRPKAEA
>K1ZFQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MSFQKRLAAKEFAVLAEMHTPKGINISRLVNDARRLKGRVDAVVIPDMDNGIMRMSALAG
GVLLQQQGIETIMHTYCRDRNRMALQGDALAAYVLGIQNLIVAGSEDMSESDHSDAKVVN
DVDEVRLIETLITLQKGKDMSGFDLDGAPSFSIGCTMAPCADSKACDAALSAAAMKIAAG
AEYIITPPVFDLAAQTDLIKKVKHLGVPVIASVFLIKSLAIAQYIANSDPSARISDDLIR
RIRKSSDRELEGIKIAGETVMAMKELTRGVLIQTLGWEHKLPEILDVAKV
>K1YYI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MKTESRLEKILAAGHLAVTSECGPPRGCQPGHLIEKAKYLEGIVDAVNVTDNQTAMVRMS
SLAASFIIKQQGLNPLFQVTCRDRNRLAMQADIIGAYSMGIDTMLCLSGDHTKFGDHPMA
MNVHDIDSVQMIQMVRDMRDKGIFQGGAEIKGPPKMFIGAAANPFADPFELRVMRLAKKI
AAGADFIQTQCIFNVPKFEKWMEGVRERGLHKKCYILAGVTPCKSLGAAKYMANRVPGMD
VPKEIVDRMASVPKEKQAEEGVTICVETIEKLKKIEGVAGIHIMAIEWEEKVQEICERAG
LLPRPQV
>A0A1I5VPG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas borbori|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGKFAITSEIDPPDSADPGEVLKRAAIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYATIMQISCRDRNRIAIQGEILGGAAMGAA
NILCLTGDGVQAGDHPQAKPVFDLDSMSLLEIARGMRDDCRFQSGRKIVTPPRVFLGAAE
NPFVPPYDWRPHRLAKKVAAGAQFIQTQYCFDIDLLKQFMSKVGDLGLLEGPDRVHILVG
VGPLASAKSALWIRENVPGVHIPDAVIKRLQGASKQKEEGKRLCMDLLQQIREIKGVSGA
HIMAYRQEEAVAEIIQATGVLEGRVPWYPGRDNPAQLNPQSPQASAQPAQAVCK
>A0A1F2UK06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aquicultor primus|TrEMBL
MGFKEEIQSGNFVITAEVGPPKGTDISEMKHHIKSLKGKVTALNVTDNQSAVMRICTLAV
AKEIMDIGIEPIYQMTCRDRNRLGLQSDLLGAAIMGIKNVLALTGDHPVLGDHKDAKAVF
DIESVQLLEVINGLNEGRDMAGLELQGATDLFAGAIVTPESNPFEPQFAKFKKKVNAGAK
FFQTQAIYDMPKFMTFMERAKELDVPILAGILLLKSAGMAKYLNKFV
>A0A2P0QMZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MQSQKKHPQLFSFEFYPPKTEEGTANLKIVHSKLAELKPDFFSVTFGAGGSTRDKTFDTV
VDIQAKGIAAAPHLSCVASTKENIRAILKNYQDKGIARIVALRGDLPSGMMSAGEFRYAN
ELVDFIRLETGDYFQIHVAAYPEAHPQSVNATEDFKNFKRKVEAGANAVITQYFYNADAY
FYFVDTCEKNGITIPIVPGIMPITQYAQLFRFSEMCGADIPRWMRKRLEGFGDDRASVQA
FGLELVTNLCQRLLDNGAPGLHFYTMNQSAPTLAILEQLKLNT
>A0A1C4K5T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. BvitLS-983|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDRVTAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>U6R969|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola massiliensis B84634 = Timone 84634 = DSM 17679 = JCM 13223|TrEMBL
MRVVDLIKSTDKTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKDL
GNGLYQRARMRRRPGTVAVAAALQNKYNITTVPHILCSGFTREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPEGNGYSHALELEGQINDFNKGLFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKVEAGAEYAVTQMFYDNRKYFEFVERVHKEGINVPIIPGIKP
FGKLSQLSMIPKTFKIDLPQELASEAMKCKTDEEARALGVEWCIHQCRELIAYGVPSIHF
YTVSAVESVKEVAKVIY
>A0A8J6JDC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lawsonibacter sp. NSJ-51|TrEMBL
MGVKAYLKQGKPLLFDGAMGTYFAARPGRAAERCELANLEHPEEVSAIHRAYLEAGCRAI
KTNTFSVGVDLAQGKHALARQIIAEGARLAREAAEPFGAFVFADLGPAPQDKEHSPAELY
CLQLDLFLEQGLTCFLAETLPTDDGIPELARYLKRRCPDAFLLVSFAVGADGVTREGALG
RELFRRTAALTEVDAAGFNCISGPLHLLRYIEGLERGDTLLSVMPNAGYPTVVGRRTLYK
GTPDYFSRRMVQIVGAGASIVGGCCGTTPEHIACAARALEGTSIRCPAAPAEKARLRVEA
GDVNPLWEKLRSGKRVVAVELDPPADDDLAPFLEGVRTLREAGVDAVTIADCPVGRPRAD
SSLLACKLKRELGVEPLPHMTCRDRNLNATKALLLGLSMEGVHNVLLITGDPIPSTDRDE
VKSVFNFNSRKLARYVSGLNGESLSTPFQIFAALNLNARNFSVQLRLAQEKEECGVAGFL
TQPVLSREALEHLIQARAVLKGKLLGGIFPVVSHRNACFLNNEISGMYVCDEIVSQYVGK
DRAEAEELALRISTRIAREIQPYTDGIYLMTPFRRVELITKILKAIG
>A0A222MYB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter avium LMG 24591|TrEMBL
MNKPSFSFEIFPPRKSDSIDKIYKVLEELKDLNPDFISVTFGAGGSANSSNTLELASLVQ
EKYHTQSIVHLPCIHLNKSDIKLILDECKKKKLSKILALKGDYIEGNQLSKDFRYASDLI
EYIKQNGDFEIYAACYPEKHKEASSFAQDIRNLKIKVDAGASTLLSQLFFDNSDFYRFQE
ACDIIGIKAKICAGIMPIANKRQILKITSMCGAKIPKKFQQILHKYENNDKAMVDAGIAY
AIEQIVDLLTNGVDGIHIYTMNNSYIARRIYEATHSLF
>K7QWA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus oshimai JL-2|TrEMBL
MKIRDLLRQGPRPLFSFEFFPPKTEAGEEALFRTIAELKAFRPAFVSITYGAMGSTRALS
VAWARRLLEMGLNALAHLTVAGQSRKEVGEVLEGLVGAGVENVLALRGDPPQGQRVFVPH
PEGFRYASELVAFIRARYGEALSVGGAAYPEGHPESPSLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRLGIGIPILPGIMPITNYQQLRRFTEVCGASIPGPLLSQLERHQ
DDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGFRPEPPPQRTPG
SPPAP
>A0A1F8L879|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium GWC2_73_18|TrEMBL
MVGGDPPPEVGPALAAVRPPPTGGRLEAVLRAGEFAVTAELDPPDSADPADVYSRLDVFD
GVVDAINVTDAAGASCHMSSLAVSALLVRAGREPIFQMATRDRNRIALQGDILGAAALGI
VNLFCVTGDRVQRGDQPGAKPVFDLDSVTLLSTARRLRDEGVFRSGRPISSPPRLFLGAA
ENPFAPPFELRASRLAQKVAAGAQFIQTQYCWDVPLFARFMERVRDLGLHERCHILVGVG
PLGSARAARYMRDNVPGVHVPDAVIERLERAADPAAEGTRICLETIAQVREIAGVAGIHL
MAYRHERLIPEIVAESGILAGRRLPPSPPAASGAVSVS
>A0A417HEN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM29-12LB|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A6B8LWC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystis rosea|TrEMBL
MFNALHPTASPNQFAISYEFFPPKTPEMETQLWQTINRLAALRPHFVSVTYGAGGTTRER
THSIVARIVRETEMKPAAHLTCVSAAREDIDAILRDYWDAGVRHIVALRGDPPTGVGSRF
EAHPKGYAHSTDLVSGIRRIGDFEISVSTYPEGHPESASIEQDLDALQAKVDAGATRAIT
QFFFDNDVYFKFLDKARGRGITIPIVPGIMPIRNFKQVAGFAQKAGASVPRWLAERFDGL
DEDPETRALIAATTAVEQVMSLARAGVNEFHFYTNNRADLVFAICHLLGVRPLREKALA
>A0A1X0RFC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus microsporus var. microsporus|TrEMBL
MKIIEKIEQAQKNNTINYSFEYFPPKTELGYANLIDRIERMAKLGPEFISCTWGAGGSTH
ERTLELCSTTQSVYGLDTCMHLTCTNMEKDKIDIALKQAKEAGIQNILALRGDPPRGHEY
WTPIDNQFTHAIDLVKYIRQQYGDTFCIGVAGYPEGHVDSPNKEQDMQYLKEKVDAGADF
IVTQFFYDPEAFINWMQNIRHIGITVPVVPCIMPIPTYQSFRRMIHLCNVKVPAEVMKDL
DEIKSDDQKVKDYGVRLAVNIIKELHKRVNICNFHISTLNLERSTRLILEQLGLIHHTEK
LTANKPSPWAPVHDPIKVEMWDEFPNGRYGDSRSPAYGENTYSLNQILPTSQAILKWGQP
QSEEDVRQLFKRYIQGELDSLPWCEESPQTETGTICQELIHLIEQGYLTISSQPAVNGAP
SDDKVYGWGPKGGYVYQKAFIEFFISDQAVSELLARLSKDPSVTFYAANRKGDFVTNVTD
PDAQNAVTWGVFPSKEIIQPTIIEKASFESWKVNDQ
>A0A1I3V7F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium albiziae|TrEMBL
MNPPRPPQIDENPAGIDLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSANPEDVYN
RAKIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
GAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVF
ILCGVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAEDQKAEGKRLCIDIINEVKEIAG
VSGVHVMAYRQEEYVAEIVDESGVLKGRQPWKREVRADDRLVADRLDHLLHDNVTETQVD
MVKTAH
>A0A397BRQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces astaci|TrEMBL
MKIIDKINEKIEKKEPFYSFEYFPPKTPAGVTNLYTRMDRMALMEPLFCDMTWGAGGSTA
SMTIELCVNAQKLSGLEMLMHLTCTNMPKGSIKNALDSAKDAGIQNILALRGDPPRGQTE
FKECEGGFAYAIDLVKYIREEYGDYFCIAVAGYPEGHSDAKDLDTDILHLKEKVDAGADF
IVTQLFYDVQKYFDFVDKCRAVGINVPILPGIMPIQNYNGFVRMSSMCGHVPDAILQALE
PIKDNDEAVKDYGVELGIQMCRDLLDHGVPGLHMYTLNLERSTRLILEGLGLTATARREL
PWRPSTLAKRAGETVRPIFWANRPKSYLDRTASWDEFPNGRWGSSESPAFGDLNESYYSH
TTASVQERKAMWGESPVTYADVYETFTRYVMGAVKSLPWCDTPLHLETKSIQERLAAVNR
AGYLTINSQPRVNAAPSDDPMFGWGGPGGHVYQKAYVECFVSPENLKRIIEKCNKMKHVQ
YHAVDVNGNSYSNCGKGTTAVTWGSFPNKEILQPTIVDTDSFMAWKDEAFSLWLSMWASL
YHDESAAHALIHQIRDSFFLVSIVDNNFVNGDIWDAFDVDVTTASAAGP
>A0A1G6WBJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella marina|TrEMBL
MTSGQLSPRRAVTPPAAVPARRAARLGTVRERLSAGAPVLSLEFMPPRPTDDADRIWRNV
RTLESLRPGFVSVTYGAGGSTRDNTIAVAARIARETTMLPVVHLTAVDHSIRELRSFIGA
LADAGVVNVLALRGDPPGDVTGKWVRHPEGLEYASELVTLLRQHGDFCVGVAAFPHRHPR
SASIEDDTAHFVAKCQAGADYAITQMIFDVDDYLRLRDRVVAAGCDTPIIPALMPVTTMR
TIARSEQLSGAPFPPRLAKRFAAVADDSSAVRALGIEQATVLARRLLAEGVPGLHFITFN
FARATTEIVAELKIPA
>A0A7Y5WR85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
MGTMLYSRGVFINQCYDELNLRSPDLVRDVHRAYVKAGAEVLETNSFGANRVKLATFGLA
AQTRELNRRAAELAREAADQGHDVLVAGAVGPLGVRLEPFGPTSAEEARAIFREQMEGLR
EGGADLFILETFGDLHEIGQAIAAAREVDPAMPVIAQMTIGVDGLTPYGATPEDVARALD
RLGADVVGLNCSVGPQTILDAIEKMAPLTRKKLSAQPNAGMPRDVGGRSMYMASPEYMAS
YARHLVQAGAKVVGGCCGTTPDHIHAMCEGVRPLSPRFARTGAPVAHVEDGKPPVLREGR
RTPDVAAVPLAERSRWGAKLAAGTFVTSVEIVPPRGVDATRMLADVAQLKRAGVDAVNVP
DGPRAQSRMGALLTSLLIEQRVGIETVTHYACRDRNLLGMLSDLLGASAVGLRNLLLITG
DPPKMGPYPSATAVFDIDAIGLTNLVSNLNHGRDPGDNAIGAPTRFVIGVGVNPAPIDLE
HELKRFAWKVEAGAEFAVTQPVFDPAQLETFLRRTEGARVPIVAGIWPLVSVRNAEFLAN
EVPGVSVPEEVIGRMRAAGEKSKEHAVAEGIAIAREMLDRVRGAVQGVQVSAPFGKVELA
LEVFRDSLDPASASAGATNAAVPA
>A0A2N3QU72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum subsp. globosum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLTEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAF
IRERRPDMKIYGACYPEKHPQADTLDHDIDNLKRKVDAGATHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDRWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWANVQDLFA
>L1LT75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida CSV86|TrEMBL
MNSLKQALRDRQFVCVMEFVPKPQRFAAFEQLMQRGHLCGWPMLAGIADRVGSNLDLSPL
DTFTALSTPVPVMPHFSGKDRERQDLLAQLERMDRLGLDQLLLLTGDRLHGHEPGQRPVR
YLESVAALGIARRARPDWLLGAALNPFKYCEEEGGAQYFKAQKKLAAGADFLILQLGFDM
ARYRDAMHWMQRQPTPRPMLACIMGLTHGRAKMLEHVAGVTVSPSMLALVAAEEAVSKVH
AQARSVDRLALQIIGLQRMGYAGINLSGVHDIAQLLALEQALDAWREKIRTDEEWALAWA
RSWQLPGVPAVTFNPPESDWKAGESRVSATPKEKLRYHLLSTLHSTLFNRTTLLSRAFAW
TVRRPLWSTQAGQRWLHRLERGVKRPLVGCDTCGSCRLEDTLYICPETCPKGLANGPCGG
TRLNRCEFGDRECIHSIKYRTAKSVGQTAVLTQRLIPCVEVEGRQRSSWPEWFAVGAEQA
ASAMAADLSPDQPR
>A0A1H5LEA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas palleroniana|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAEQLARYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITQMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A6I1WT59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas helleri|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKDDLRGLLNQYKGAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDISNFVRKANAGADSAITQYFFNADSYFR
FVERVRAAGVMIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDANSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A5T0SZZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYAFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A6B3P0Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas brassicae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARTLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHIEVAAYPEMHPQARHFEDDLLNFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDAKSIQAFG
EQVISDMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A5T1MFU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKFLALRGDVCNDLEKSKDFSYASDLISF
IRKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKKQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A2E5QRW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibacillus sp|TrEMBL
MLSKLIARSEAFLKGMMFDCRACGQCVLSQTGLICPMSCPKGLRNGPCGGTLEGECEVYP
DRECVWVRIHRRTGKDSFTLPDLIPSPDPSLSFTSSYLNLLSGKDKPGREPMPYLELGTH
RVRLPVQTASGFEAKLRSGQFVKTCEIRSPRGPDLSHFREEACIIRDRFDAVNATAYLNA
KPSLPSPVAAAELAKLGMEPISQATCRDHTKTSFVSELIQNEMNGVHNMLCLTGDSYSSK
PKIKQVFDMDSTLMLYEARHLREEGSIHFLQETVLQTPKIFLGAAINPFTQPANVPIRRL
KQKAAAGADFIQTQAILDVTGFESFMQRVTEEGLDQELFILAGIPVVIAAGALDMLPRIP
GIRIPPEIRQRLEQAENLKREGVILAREMVRRVRAIPGIAGVHLMLFGSDHRALLDVIEE
LED
>A0A532AXH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPKRLKDVLEQGQFAVTIEYNPPKGTNIASVLENAKALVGRVHGVNVTDNTAAVVRA
GSLSVCRLLYELGHDPVMQMTCRDRNRIAMQSDLMGASMLGIRNILCLTGDYPTVGDHKD
AKPVYDLDSVQVMQLVQGLNNGRDMAGNKLDGSTAFSIGAAVTPEADPLGPMLAKFELKV
KAGAQFFQTQAIYHPEQFASFMKAVRPFKAKVLAGILVLRNAKMAEFMNANIPGVSVPQE
MIDELKAAGPERAEDVGVDIAVRTIKAVRPYCDGVHIMAIKATHRLSDIITRAEVG
>A0A420V9Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces xinghaiensis|TrEMBL
MALGIPSTRTDHARTVRDLLASGAQSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGSSRDGTVRATERIATETTLTPVAHLTAVNHSVAELRNVIGSYAGAGIRNMLALR
GDPPGDPMGEWVPHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSPDWESDIRHFVD
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSMGIEYATELCARLMGEGIPGLHFITLNHSTATLEIYENLG
LHQRPR
>A0A5P2X332|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces spectabilis|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNSLRRVEAVAPSFVSV
TYGAGGSTRAGTVKETEQIVADSTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVKHPEGLAYAAELVQLIKESGDFCVGVAAFPAMHPRSADWDSDVRHFVD
KCRAGADYAITQMFFHPEEYLRLRDRVAAAGCETPIIPEIMPVTNVRQLERLPQLSNADF
PPALKERILSAQDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHQQQA
>A0A426W7I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTTNRSFSFELFPPKTEKGFENLKTAVNQLNALNPEFFSVTYGAGGSTQDRTFASVDWLR
EQQIETAPHLSCIGSSREEILQILDRYHEQKIQRLVALRGDLPSGAGLGSLGELNYANEL
VEMIKERYGDHFYIEVAAYPEFHPQANSAKADLKNFKRKVEAGADGAITQYFYNPDAYFC
FVEECSDMGIDIPIVPGIMPITNYVQLARFSDACGAEIPRWVRRRLESLGDDLEGIRAFG
AEVVTELCRRLLDGGAPGLHFYTMNQATPTLKIWNNLGL
>V4KY68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp. PB-SRB1|TrEMBL
MSATTTKSRLEQVLKSGHQAVTSECGPPRSSDAAHIIEKGELIKDHVDAINVTDNQTSVT
RLCSLAACVHLKLKGLDPVLQMVVRDRNRIALQSDLLGAASFGISNVLCLSGDHQSFGDH
PQAQNVFDLDSMQLVQTVRYMRDEQKFLSGDEIKTPPNMFVGAAANPFGDPFHIRVPRLA
KKIAAGAEFIQTQCIYNLAKFELWMEGVRARGLHEKVYILAGITPMRSVGMARYLQKNVP
GMDVPDELIERLKGVEKKKQSEEGITIAVESIQRLKEIEGVAGFHVMAIEWEEKVPEIVE
RSGLYPRPKVNG
>A0A7C4I976|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTRRTFSFEFFPPKTPEGAEKLRAVRARLAAVDPAFFSVTFGAGGSTREGTLATVLEIHA
EGRPVAPHISCIGSTRASVRDLLRKYRDVGIRRIVALRGDLPSGAAGGAGDFSYANELVE
FIRAETGDWFHIEVAAYPEYHPQARSPADDLSNFVRKVRAGADSAITQYFYNADAYFRFV
DDVAALGCTVPIVPGIMPITNYAQLARFSDACGAEIPRWIRKRLESFGDDRESIRAFGLD
VVADLCERLLAADVPGLHFYTMNQAEPTLAIWQRLGLPGG
>A0A2D9UL36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp|TrEMBL
MSKRISFEFFPPKTEQGREKLLNTQQKLLAKKPEFFSCTFGAGGSTRDYTRQMVDLLREQ
HADTAPHLSCIGQSRDEIMELVNGYKESGVRRIVALRGDLPSGMGYAQSEVKYADDLVAL
IREETGDHFHLEVAAYPENHPQSRSFDDDIAHFQRKISAGADSGITQYFYNADAYGYYMD
ELRRRGCDAPVYPGVMPILNVANLFRFSDNCGADIPRWLRSRLDDIRDDEQAVKAFGEEV
VTRLCERLLAMGAPGLHFYTMNQSGPILRVLDNLGL
>A0A0D6GBI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLYGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A356VZT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKLIQIISQKKPSLSFEVFPPKNNGRYESLRSAIARIAELSPSYMSVTYGSGGGTSSTTV
SIAAALQKSYHVPVLAHLSCIQSTREGVRSQLDALRAAGIENILALRGDLPPGSEPQAGW
YYRFASELVREIRRYGGFCVGGACYPEGHPESRTQMEDIAHLKEKVEAGCDFLTTQMFFD
NNIY
>A0A366QMF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella moniliformis|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIESHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKNLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>S3UCX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter colistiniresistens|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKTVHQELQLLNPEFFSITYGAGGSTRERTLAAINEFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A2P5VTD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium barbadense|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DALVKNCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGAFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A2E5UYE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanicaulis sp|TrEMBL
MSADGSTIQPRNGLNVSFEFFPPKTEAMEETLWESISRLEPLSPNFVSVTYGAGGSTRDR
THRTVRRIVRETGIRPAAHLTCVSATRDEIDDVIRDYWSAGIRHIVALRGDPPDGIGEAY
TPHPGGYANAAELAAGIRKIGDFEISVGCYPEKHPESRDFDYDIDLLKQKIDNGATRAIT
QFFFEPDVYFRFRERAERAGITIPIVPGIMLQANFNGLKRMAGLCGASLPAWLHEAYDGL
DEDAGTRKLVTAHVAAKLCSKLQAGGVDNFHFYTLNRAELALSTCQLLGVKAEQREAVGV
A
>A0A1B8NYG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas elongata|TrEMBL
MSAQQSPLDISFEFFPPNTDAGRDKLMRARDALATRDPRFFSVTYGAGGSTQHRTLSAVK
AVRECGIDTAPHLSCVGSEKAQLRDLLKRFQEDGVKRLVALRGDLPSGMGGVGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFERDLENFARKMHAGADIAITQYFFTAEAYF
HFVDRARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAF
GEEVISGLCQRLLDGGAPGLHFYTLNQAEPTLKVLDNLRT
>A0A381F7S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium indoltheticum|TrEMBL
MKITDHIKNANGKALFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTLGGHASAMDLVNQINNLGRGKYLHNDEQICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVTKAREMGITVPIIPGI
KPIATKNHLKLLPQVFKIDLPEDLINAVESAKNNEAVKQIGIEWAISQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A5I0N5Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Coeln|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1E3XK15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella multocida|TrEMBL
MSYAKEIDTLNQHIADLNGKINVSFEFFPPKNEKMESILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLEAAPHLTGIDATPEELIEIAKDYWNSGIRRIVALRGDEP
KGYAKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLVKMAAITNVKIPAWLAKNYEGL
DDDPTTRNLVAASVAMDMVRVLSREGVNDFHFYTLNRSELTYAICHTLGIRPSSE
>A0A7C0WJB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSFRETLESGKFTVTAEVGPPKGTAIADMIHHMELLKGKIDAVNVTDNQSAVMRICSLSV
CKIAMEQGLEPILQMTCRDRNRIGLQSDLLGASVLGIKNVLCMTGDHVSAGDHKDARPVY
DLESVQLLKTVDSLNNGRDLGGNEMKGATAFFQGAVVTPEANPLEPQLMKFEKKIRSGAR
FFQTQAIYDIEKFRGFMEFARKFPVKILAGLVVLKSAGMANFLNNYVPGIKVPREFIDEL
KEAGKENALDTGLSITARHIKQLKDEGVCDGVHIMAIGMEDKVPVILERAGLL
>A0A6G2JGV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MNISLLDHLRSSLLVADGAIGTMLYARGVPMEVCFDEINLSRPDLIRKIHEEYVDAGARL
IETNTFGANALSLSKYSLEDQAETLNARGVEIAREAVSNRAYVAGAVGPARGLPHREYTE
ADYRRVYAEQIAALAGGGADAIILETFLRLDDLKAALAVSKEICGLPTICQLAVDQYGQT
DDGFEVAEAFDQLRAAGADVVGVNCRSGPKGLLDALAPVPLAEDLVLSAFPNAGSPVYVD
GRFIYEATPEYFATSALRLRDQGVRLIGGCCGTMPEHVQAMARALEGQEIVTRKKVLPID
VRVPARPARPARPARPARPVPAQPAVEPSIVELVKERVTVIVELDPPRDLDHGPIVRGAK
ALKKAGADALTMADNSLAVTRISNMAIGQIVKEEAGIRPLLHITCRDRNLASLQSQVLGL
HALGIDHVLAVTGDPVKFGDQPGASNVYDVSSFELIRLIKQMNEGVGFSGRSLNGRTAFT
VAAAFDPNAPNLERRIRRLERKVEAGADMIMTQPLFDRRQAKQLHEATRDAGVPILPGVM
PLVSDGNTEFLHNEVPGFVVPGDVRARMARVGRGRKARREGVAIARELIESVLTYFNGLY
LITPFNRYPMTVELTKFALQATTRKEHG
>A0A5P3IDE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis bv. diacetylactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNLIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTF
>A0A8D0MGJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSL
CQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPI
FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQEL
TSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQ
PNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKG
ENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPS
RMLIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEQ
>A0A3Q7Y951|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ursus arctos horribilis|TrEMBL
MMIASTAVNYCGLETILHMTCCCQSREQITGYLQKARRLGLKNILALRGDPVGDQWEEEE
GGFSYAADLVRHIRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQL
FFEADTFFQFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKD
NDAAIRNYGIEQAVSLCQQLLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPW
AVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLK
SKSPREELLKMWGEELTSEESVFEVFAHYLSGEPNQQGYKVTCLPWNDEPLAAETSLMKE
ELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVL
KKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFA
LWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLENCLWQVVEDTFELLNQPAPE
GETEAL
>A0A7I0ENH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHVDHPVYILGTIGGLAGDTDATVQR
ATPATIAANVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENFAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSASVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFIGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A0I9R317|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brugia malayi|TrEMBL
MDAVRDDNEGEMSPTSSTDGFVVSSSGNTSDVVIPRSCSKKWGESRTDWVANGTYVPLRD
RIKKRIANGIPFFSLEFFPPKTTNSVANFFARLDRFREGNPMFVDIAWHFGSDPGNISSE
TSSSSVAAGCLDYCGMDTMLHITCCPYTKEQSIRHLEQSKALGLKNILALRGDLPRQDEN
PVLYKYRALDLIRWIKEEYNDYFTIACAGYPAGHPEAPSYRADLLYLKAKVDAGADFIIS
QIIFDGEVFKNFLRDCREIGITVPIIPGILPIQSYESIRRVAELSQLVIPDSILTSLEPI
KNDDDAVRNFGIWHAVTLCRTLLSNGSATSIHLFTLNREASSREILQQLGLWPRSPMRAL
PWRLFGESHPVRCKEDVRPIFWSMRPKSYVFRTREWDEFPNGRWGNSSSPAFNDLKDYYL
FYLKGQPTRDEQLRMYGERLETLADIQKVFVNFITQNINENGVKVSQLPWNEQHDGIRAE
TSLIKDQLLWCNSNGFLTINSQPSINGAPSTDPFVGWGKPGGYCYQKAYLEFFTSQANAE
VLWSLLPSYSRLNCHIVNHDATIDWTNTETTMPIAVTWGVFPGSEIAQPTVVDPLSFRVW
KDEAFSAWLNWSSIYAEGTSSRCLLEKIYNEYCLVTLVDNDYPKSTIIFDCLAQLVNR
>A0A432S4C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Persephonella sp|TrEMBL
MKISEKLKNVKTSISFEFFPPKTEEGEKNLLKTVKDLENLNPTFVSITYGAGGSTRDRTK
RIVEKLAKDTDLTVMAHLTCIGHTEKEIKEILDYYKNIGIRNILALRGDIPLEKLKEGYK
EEEIFKSCKHANELVSFIRDNYKDWFSIGVAVYPEGHPESPNLERDVYYFKKKVEAGADF
GITQMFFDNNYFYKYMELLDKEGIKIPIIAGIMPITNFKQIRKFALMCGATIPESLIKKL
EKYENSPEETEKIGIEFAVEQCIDLLKNGVKGLHFYTLNKSKATLQIYNSIKHLLD
>F2TKH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces dermatitidis (strain ATCC 18188 / CBS 674.68)|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDTALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDDQDDPELLMEHLKEKVDAGGTF
IITQMFYDVDNFLTWVEKCRQKGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEAL
EPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQATKMILDELGLIPSHKTP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSLKELSEIFIRFLNGSLDRLPWSEGAVTEETEIIKSDLLD
LNRKGFLTINSQPAIDGMPSSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNS
DLTYYCVNKKGELKTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHAPSSLSRRLIEQVMDTWYLVNIVNNDFHKTHDIFNLFKDLKVENLDTEIEPIALAAE
SVDIAQQNGQLPQTEVNDSCTEATKSMEERNSN
>A0A0N8P3J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHVDHPVYILGTIGGLAGDTDATVQR
ATPATIAANVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSASVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFIGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A174G7T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster clostridioformis|TrEMBL
MDDAEGRERRLKIREILAVGKPTLSFEVFPPKTEDAYDSVEKAAAKIAKLKPSFMSVTYG
AGGGTSDYTVGIASAIKEEYGVTPLAHLTCVSSTREKVHHVLGELKERGIENVLALRGDI
PQDGSTPKEYHYASELIREIKKAGDFCIGAACYPEGHVESANKSVDMDYLKQKVEAGCDF
VTTQMFFDNSILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTCLPSRFMSIV
DRFGDNPAAMKQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A0B7GE40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella variicola|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A413JK30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium symbiosum|TrEMBL
MKIKDILAAGSPTLSFEVFPPKGEEAYESVEKAALEIAKLKPAFMSVTYGAGGGTSRYTV
GIASDIQRETGVNTLAHLTCVSSTRSEVKSVLKQLREKQIENVLALRGDIPADGPIATDY
RYASELIYDIKQFDENLCIGAACYPEGHVESVNKTADIEHLREKVEAGCDFVTTQMFFDN
NILYNYLYRIRERGITVPVVAGIMPVTNVKQIKRICQMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAKIGDSLSEIL
>A0A0H3KAS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus (strain Newman)|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLYGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A4V2K5Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dichomitus squalens|TrEMBL
MKLTDRIAQHDPNRLFYTFEFFPPKTDQGFENLVSRIARMVALNPLSVSVTWGAGGTTKD
RSLDLAGLTQLEHGIDTTLHLTCTNMVQGTVDAALREAKERGIENILALRGDPPRGSEHW
IPTDSRFQHGVDLVRYIKSTPEFAHFCVGVAAYPDGHPDRDTTEDRELDHLKEKVNAGAE
FIITQLFYDVNGFLQWVKKVREKGITVPIIPGIMPIQTYASFLRMTKLCATSVPPKMMSD
LVPIRHDDQKVKDYGVRLAVDMIRQLQAGGIQGVHFCTLNLEKSIIRILEALGLAGDVSH
SSNKLIADDAVPPERTVTPHTAADRATKELATSVPEPDASKGEINSAADWDDFPNGRFGD
FKSPAYGETDRWGSSALQSKAATTPVSHWGNPKTVNDLTSLFLRYLHSKITTTPFSSTPL
SPESLMIFPHLEKLTSKGWWTVGSQPAINGAPSTDEVVGWGPRGGYVYQKCFVEFFVAEQ
DVNRIARKVDSEGAGWISYFAGTAKGDVLTNVPEGGRNAVTWGVFPGQEIAQTTIIEKES
FLSWKDEAFSIWDEWASFYPPESQERRLLEDVRDKRWLVSLVHHDYMDPNALWTFLFKGA
TPLL
>A0A2D7V3A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MNSGTSIRGLFEEERPLFSVEFFPPKNEEGGERMIRTATALQPHRPDFVSITYGAGGGTR
KTTMRYAKILKEEHGFEVMPHLTCVGHSKDELLEILEGFAEAGFRNVMALRGDPPQGESE
FRVTEGGLRYASELVALIRDHFPEFGIGVGGYPEKHPEAPDFETDMKNLKTKTDAGADFI
TTQLFFDNQAYFSFVENCRKAGILIPILPGLLPALSLGQVQRFCKMCQAFLPPELEKQLE
ATDPQKHPEIGSKWTLNQVSELLRENGPGFHLYALNKSKSTLAILEGLSLGS
>A0A0A8TFM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium freudenreichii|TrEMBL
MLDNYRPADLAPARRSNTDTTQTIAELLARAERPTFSVEFFPPKTDEGARVLHEAIEKLE
PWNPDFVSVTYGANGSLRDRTLAAVRDMVASTKLRVVGHLTCTGQSVDELKSVIDAYGDL
GVHHILAVRGDMPGGPRQPWEPHPQGLKNATELVELVKSRGDYCVGVGAFPDIHPGSTPE
QDVRVLHDKQDAGAEFAITQLFFRPSAYYDLIDRMRADGCTLPVIAGMMPVTAISQLDKF
AELSGVPLPASVTERLMAVANDPLAVRATGAQICAELASDLLERGAPGLQFFTRNRSAAT
REILAILLARRPW
>A0A2G4ILG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MSIVDVYENGRFGLSFELFPPKNPDSEQLMWRTVEELVAFQPAMVTCTYGAGGSTRDKTL
DVIEGVRKRYHLPVASHLTCVGSSIDELRGYLQAARSRGVSAIVALRGDPPQGATVFTPV
AGGLCYAAELVALIRAEFPEFGILVAGYPETHQEALSPDADLKNLKQKCDAGGEVVVTQL
FYDNADFFRFRERCVAEGIRAPIIPGVMPVVNYAQIRRISTLCKARLPESFTRAFEAAGE
DEASQFEVGVDFATRQVQELLDGGVPGIHFYVLNRSPATVRVLQQVGMGR
>A0A3Q9KQ13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseoviridis|TrEMBL
MNPATTAPVAVRAPLLEDFSLEMTAKDGPRLEEARALVPAGTRVNVTFLGNEDLELRLAA
ARTVKRLGFVPVPHVSARRLESREELEKLLAGLRADGTGDHLLVVGGDPATPHGPYEDAL
AVLRTGLLAEYGVRHVEVAGYPEGHPAIEERTLWSALADKRAALTGQGLTTGVITQFGFD
VDPVLAWIERIREQGVLIPVRVGVPGPAGARRLVAYAARFGVGTSASIARKYGFSLTNLM
GMAGPDRFLHALAERYDAGRHGDVKVHFYTFGGLRATSEWIAAFRP
>A0A537FFP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MLLKLGELARQRRLVTVEVIPDRVTKEDLSSLNGRVDAITIPALRNGNHDSSYPVTFNVS
PQQRSLASAVLTRGAGIETVPTLTCRDCREEDVVKVQGLLLKGLENILVLYGDPFSDRER
DKYEFAKTADLIRRVVDSANGKRPSIGATTNQYAQDTESEVLRALTKVEAGADFVITNMS
FDSEKVLDHRDALLSAGLNVPLFIQVSIPASLNNIVYVTQKFGIPLPAPVMRRLSADGLQ
VGVELAGEAFEKLEDEAEGIHFSYLLRRKSPVTAYLRLLDRIGRRRTVLAAPVLDIPGQV
LGS
>A0A0N8T9K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. aptata|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSTEDLRKLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VKFIREETGSHFHIEVAAYPEMHPQARNFEDDLQHFVNKANAGADSAITQYFFNADSYFT
FVERVEKLGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLQLPR
>A0A2E2AQA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MASVAQFYTADRKGLSFELFPPKTEKGGVSLMRHTEALMQFAPDYITCTYGAGGSTQTKT
MDVITQVKSTFNIPVASHLTCVGSTQDDLRQYLENASQQDIDFLVALRGDPPQGDTEFKA
VAGGFRYANELVEFIRAEFPNFGIAVAGYPEVHQEAPSAEADLENLKRKIDAGADIVITQ
LFYDNKDYFEFCDRCVAAGINIPIVPGILPVTNLNQIQRITSLCGSKLPESFIQRLGEKG
EDNTEWQFEAGVELAIAQVQDLIDNGAPGVHFYVLNKSQATLRVLETAGW
>A0A2G2HTH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Henriciella sp|TrEMBL
MSHLSVATRQGEKGPNVSFEFFPPKNETMDERLWECVRRLEPMAPHFVSVTYGAGGSTRE
RTHDTVKRIVTDTRLTPAAHLTCVGAPREEVLQTAEDYYEAGVRHIVALRGDAPQDEDYD
KPEGRYTNVVDLVSDLRAHRPDLGKVFEISVACYPEPHPDSRGWEQDLAHLKRKQEAGAD
RAITQFFFEPEVYFEFVDKARAAGITMPLVPGIMLQPNFNGLKKFAKMCGASLPDWLHKL
YEGLDDDADTRDLITANVAAELCHKLADGGVEQFHFYTLNRANLALSTCHLLGLKPATAE
AA
>A0A413PWG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum hallii|TrEMBL
MRMNIREYLENHKLLTDGAMGTYFDSIEKENYICSEEANITNPALVREIHRSYVKNGAQL
LRSNTFLANEGTFLSLTQAKAEAFENITLKQLIIAGYQLAKETAQEVYQEEYPIFAAADI
GPILEERDSEEADILQQYYEICDSFLEAGADIFVLETFPDTQYVLKMAEYIRKSCPEAFI
IGQFSLTPTGYSRTGFHYKTILQEATQSGLLDGAGLNCGVGAAHMKKFLKSYIEEFGVPE
DMVLTSLPNCGYPQIVRGHAVYSDSVPYFGEKLGEISELGVQVLGGCCGTTPEYIGEIYK
TVFQAKKTEGAVKIPTKIVWGDVTKRVQKRKEAAVHITQAGEQKEAIKEKQVTNTFRQKL
EMGELVCAVELDPPFDTDDTKLLNGAKALLSTKADIITIADSPLARSRADASLMAAKIKM
TTGMDVMPHLSCRDKNRIAIRSGLLGSYASGIRNYLFVTGDPVAREDREFTKSVFDFNSI
RLMKFAQSMNQEVFKDDTIFYGGALNQNGAGPENIAGRMLKKMEAGCRYFLTQPVYDKEG
IERLTFLKERTGAKILIGIMPLVSRRNALFIKNEMPGIHVPDEVVAKYKEGASREEFEEA
AIEISKQIIEMGKGIGAGFYFMTPFNRVSLVKSILEYV
>A0A2V6VT35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFDRRLAAGPLLCDGAMGTLLYARGVSIDACFDVLNVSQAKVVQSVHSEYIAAGADC
IETNTFGANRFKLAVHGLASDVHQINLRGVKLARDVRESMGRDVLVLGSVGPLGKYLAPL
GTVTADEARAAFREQAEALLEGGIDAFVVETFSDLTEIALAIETIRTLTDLPIVAQMAFT
DEGVTFAGRSPAEVARTLRELGVRALGANCSVGSSTLYEVLEAMGPEARDVPLAIQPNAG
LPHRIGERLMYLSSPGYMADYAGRMIDAGARIVGGCCGTTPQHIAAMRRVLDARAPASKA
EPRPTSAARVIEALETPGLRTTLAPTLLGRKLEQRSFVVSVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLPTAILVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALGIRNILAMTGDPPRTGDYVNATAVFDVDGIGLLEVLRRMNEGMDATGNGIGEPTSFCV
GAALDPGAPDPGREVERFHRKLEAGARWFQTQPVYDLEVLDRFLARVVGSPVPVLVGVLP
LHSFRHAEFLHNEVPGITIPDGVRARLRAAGDGALRAGIDMAQQLVGEIRSRYAGAYLMP
SFGRFEVVAEVLDVLR
>A0A285AVQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella grimontii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRTIAKDYWDSGIRHIVALRGD
LPPGSGKPDMYAVDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A261AYF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis remanei|TrEMBL
MTNAGGTHVAETQETIKKIDSLSTMPYCGIDTDDNTGVEERATLETGKSWSPKHYELLHE
RIERLIDEKQPFFSLEFFPPRFVNGVPNFLERVERLSEGGSVFVDMTWHMGSDPANIDKV
TSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPGTEL
QDTHQFRALDMIRWIREEYGSYFSIGCAGYPLGHPQAPSYKADLMYLKAKCDAGANFVIT
QLFFEPETFEKFVRDCREIGITQPIIPGIMPIMGYESIKRIATLSQLEIPQHILDDLEPI
KHDDDAVQKYGTERCIAMCRRLLDNGSAPSIHLYTMNREGSIREILKALGLWKLEGDRVF
PWKNRSQHPIRCLESVRPIYWSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLS
NLTTLRNGDDRLSMFGDNIDSIEDVKRVFINYITQTPNAAGKKVTVLPWTEAETGVQPET
SLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSEK
LIQIIQRDFPIRVNYHAIDKDSTFDQTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRA
WRDEAYQMWMAQWGDFYPKESKSYGVIKSIHDTFRLVTLVDNDFQKPSVLFDVLQTALEE
LRK
>A0A139KF34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides thetaiotaomicron|TrEMBL
MRVIDLIHNSEKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLFWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEVLKCKNDKEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A534IYS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNAESGRTPIRVSFEFFPPADEAMGAMLWKSIERLAPLAPRFVSVTYGADGSTRERTHNV
VTRIQRETPLTGAPHLTCIGASREEILEIARGYWDEGIRHVVALRGDPPQGEGARRPNPR
GFRYASELVAALARLAPFDISVAAYPEVHPEAASAAADLENLKRKIDAGATRAITQFFFD
TDAFLRFRDALAAAGVHAPIVPGILPITRFPQVLRFAKACGTSVPGRLHERFAGLDDDHE
TRRMIAASVAIEQVEALRRHGVSEFHFYTLNRAELTYAICHALGLRPHARSASAARQEAP
A
>A0A2J8USK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pongo abelii|TrEMBL
MDHRKARVLPAGHYCPSLGIWSSHVGSVRSSVPPSISRNPAMVNEARGNSSLNPCLEGSA
SSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDICVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDTLELLNRPTQNAREMEAP
>A0A2N7X7X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trinickia symbiotica|TrEMBL
MNPIEISFEFFPPKTSEGVEKLRATRGQLARLKPKFVSVTFGAGGSTQEGTLDTVLEMVK
DGLEAAPHLSCIGSSKDDLRAILERYRANGIRHIVALRGDLPSGMVELGECRHASDLVSF
IRAEHGDWFWIEVAGYPEYHPQARSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DSRKLGVEVPIVPGIMPITNYTQLMRFSENCGAEVPRWIARRLESFGDDREAIRAFGLDV
VTQLCERLVKEGAPGLHFYTLNGAAATKAICERLGYGHGA
>A0A380UA53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MSLLAQYFAQQQFCVLVEYLSSHQAQWPVKAQFAGFPAAMTLADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDAKTQGQKNLLLLTGDKLKQHCYSHDLEPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMTAL
QDAHAFLARHQYAQKILACVMPLTLARAKFMLKHKVAGIVITPHMLQVLQQEKEQSLSDH
VYMRCALQILMCRHLGFAGVHLSACHQPEEQSLLERYIEEYRHLSFAECERLWNTLWQVQ
TGTEFHPKLTYYSRPATSSQIIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDRSRANQ
VLLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDCCEFGDRECI
HSVKARLAKAVGQTKILKEKLIPTVSIAVRGTSSWKNWYVESTG
>A0A538BKI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTRPPGRLATLLARGGFAVTGEIVPPKGASGDPVSEHARGLVGYVDAVNLTDNPVASAHM
SPLAGVRFVAEAGIEPTVQLTVRDRNRLGLTADLLGAWALGARNVFCLSGDPVHVGDHPD
AAVVGDLTVGEVIGLARRMRDDGTTLANTELADPPRYLIGVADVPFAEPYDPSRLESKLD
AGADFVTTQIVYDAERLAGWAEAMRPRGLFERAKVIIGVTPLRNAKQARFMDEKLPGVRV
PSPTIAALEAAGEDAGAVGMDLTVQLVEAIRTIPDIAGIHVMAMGHDAVTRDLVERTGLF
PRPTV
>A0A6L6F197|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTHPAGGPDLGTLLAQGGRSFSFELFPPKTDEGERALWQTVRDLERLHPTFVSVTYGAGG
STRDRTVRITAEIAEQTSMVPVAHLTCVGASREELRGVIAEYADAGITTILALRGDPPGG
PTAGWTPHPDGLQHADELVELIKSLGNFTVGVAAFPEGHPSSPDLDTDARVLAAKQDAGA
EFAVTQFFFRSRDYADLLERASAHGVSMPIIPGLMPVTNVAQISRFAELSGAAFPPELAA
RFEVVKADDDAVRKLGVEIAVEISNELLDMGAPGLHFYTLNRSTSTVQVYEALGLGSR
>A0A2S9KIK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malikia spinosa|TrEMBL
MGLPLSFEFFPPKTPEGAAKLHAVRQQLYSAKPEFCSVTYGAGGSTQDGTLQTVQAILDE
GQQGASHFTCVGASRESVRDKLALFKSMGLRRLVALRGDLPSGYGGMGEFRYAADLVAFI
RAETGDHFHLEVAAYPETHPQAKSAQADLQAYAAKVKAGASSAITQFFFNTDAYFRFVDD
AYKLGAEVPVVPGIMPITNSAGLLRFADSCGAEIPRWIRLRLQGYGDDVESIKAFGLDVV
TDLCDQLRNAGVPGLHFYTMNQSAPVLEILRRLDLG
>B4QQ56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila simulans|TrEMBL
MHAIQVPAGGWSPAAASYIPCVTFAPDQNETAVTEQRIGTLVAERTSQRRLFYGIEVMAS
GPSGRPTCLDFNHFLPLLPTFVSVVWLSQRYWDVEPVGQVESLQLAQYLATRIPVLPHVS
AYRMSRQRLDQILALNFSSLLAVRGDQVHEDQDFLISYPMVEQSRRQRGEKISVCVGGYP
EGYTSLGDIPQNSAKNMEFLKAKIDAGADCIITQICYRPEVIVQFVKDCRAAGIAVPIVV
GLMSHESFRSYSMIEQIAGVHLPDDLREQLDQLHSAHMKDMKSDQDLIRRFFVSLTVRTV
RHVLDADVGVWGFHFFTLNRFKSVQAVLQELRDLDLLKDAEKDTKGSKK
>A0A173UFD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium ramulus|TrEMBL
MIREYLKEHILITDGAMGTYYDRKKSENGRIAEEANLLEPELITRIHEEYLEQGARLIRT
NTFAANHAMALGRGVRDRREQDAYVKHVIRAAWKLAQKAAENRPEEIFVAADIGPAAENL
FSEYETDPAAEYRFLADCFLECGAQIFNFETFSDIKYVAKTARYIKEKCPEAFVMVSFAA
NRNGYTTQGISISRLFAEAAQTPEIDSYGCNCLLGAAHMYKLIKAQNLAGDKFIQVLPNS
GYQQIVRGQAGHADGVHYFADKMEQMVELGVNIIGGCCGTTPKHIRMLCEKLAGKAPYEK
LPVVEKGGEDAVSQTRNNPFMAKLQRGEKVIAVELDPPFNQDAQKLMEGAFQLKQSGVDI
ITIADSPLARARADSVLLAAKVSAMVDIPVMPHIACRDRNRISMHSTLLGAHINGIRNLM
IVTGDPVPSGERDNTKSVFDFNSIRFMEYVKELNQEIFLQDAFSYGGALNQNQANEDQVM
KRMQKKIDAGLSWFMTQPIYSDEEVEKLGRMKQELNTKILCGIMPLVSYRNAMFIKNEMP
GIQVPDEIVAQYRPDMSRAEAEDVAVRISLSIMEKLEEVADGFYFMTPFNRVSLITRIIH
ARKPQ
>A0A3C1TEH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Runella sp|TrEMBL
MTKITDYIQQANGKTLFSIEVIPPVKGNNINELLGNIEPLMDFKPPFIDVTYHREEYIEK
PLADGRIQQIVTRKRPGTIGICASIMHRFGVDAVPHVLCGGFTKDETEDFLMDLHYLGID
NVLVLRGDPAKPYKTFKPKTNGHAYASELVEQVVNMNKGQYLHEEVEPLAPTGFCIGVAA
YPEKHFEAVDFDTDFDYLKQKVDLGADYIVTQMFFDNSKYFDFVQKCRAVGINVPIIPGL
KPLSTKKQLGILPKIFYLHMPQDLVKAVEGCENDAQAKQVGIEWCTQQCRELMDFGVPVL
HFYTMGKSDNIYKIASSLF
>A0A520Z9R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIKNSKKTIFSFEILPPLKGQNIQSIFDNIDPLMEFNPPFIDVTYHREEYVYKEV
ENGLIQKKIVRKRPGTVGICSAIQNKYQVDAVPHILCGGFDKEDTENFLIDLDFLGIDNV
LALRGDAVKSEIYFKPEKDGYQYASDLVKQIVELNKGHYLDEELQNKSKTDFCIGVAGYP
EKHAEAPSLDSDIHFLKKKIEAGATYIVTQMFFDNAKYFEFVDKCRKRGITVPIIPGLKP
IATKKQLNLIPHRFNAQIPDDLIMAIVKCENNEAVRQVGIEWAVEQCKELIKEDVPVLHF
YSMGNSSNIKAIASQLF
>A0A1E7RBX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter qingfengensis|TrEMBL
MSKSIPFSFEFFPPKTDIGAEKLRVVHQELQLLNPDFFSITYGAGGSTRERTLAAITDFN
GKGSPIAPHLSCIGDDKSRIAELLDFYQSIGLNRLVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFNIEVAAYPEMHPQAENFDQDVQRFVEKVQAGANAAITQFFFNPDAYFYFI
ERIHKAGVDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSKSIQAFGHE
IVIKLCERLIAGGAPSLHFYTMNNTYPTRQLIKDLDLA
>A0A415H4L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea formicigenerans|TrEMBL
MTCKIRDILKDQTPQVSFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKN
TVSIASHIKDDFGVTSLAHLTCVSSTREEVHQVIDKLKEKKIDNILALRGDIPKDNAFPL
PNQYRYACELIEDIKQQGDFCIGAACYPEGHVETEHKKDDISNLKTKVDCGVDFLTTQMF
FDNNIFYNFLYRIREKGILVPVLPGIMPITNKKQLRRSMELSGTAVPQRFLAIIDRFGDD
PEAMKQAGIAYATDQIIDLIANGINHIHVYSMNKPDVAAAIMNNLSAILKVED
>A0A0K0HX48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hafnia alvei|TrEMBL
MSFFHANQREALNQSLAELHGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGGGKPDMYACDLVSLLKEVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEVHSPI
IA
>A0A8E0QW02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus udagawae|TrEMBL
MEKITDKIAALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCLGVAAYPEGHPVDSYQDVQDPVRDLPYL
VEKTLAGADFIMTQLTYDIDAYTKFEKMLRNHESGAFKTIPIIPGLMPIHSYKILTRTTK
LSHVQIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIRKIPCPGFRGFHFYTLNLEKT
VSFIIERCGLIPDDPEDFDAVVDDDYTTAPTGAQSRSLFRRRASSVNSLPHNRVIVDRLQ
VPSDGSSRASTTHEAPATSAGMPAMPPDRNTTLQISEGQGALGREATWDDFPNGRWGDAR
SPAFGEIDGYGPSLHVSGTVARRIWGYPVSREDISALFRRHVSGDLYIVPWSEGGAEENG
SGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEF
FCPSKDFQTVLKPLFAKHGHEKLAWFATNTKGEFESSLPADPADADTIEMNPNNVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAYRIWDEWRRVYPRGTPTERLLDEIKNDVWLVCVV
GQDFGAGTEGGSEEEQQETKWMWNVLINSQ
>A0A0R3R4L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brugia timori|TrEMBL
MVELLSSQKEHSCVPEMIANLIELLDLIKVFLPAVYSSVVIPRSCSKKWGESRTDWVANG
TYVPLRDRIKKRIANGIPFFSLEFFPPKTTNSVANFFARLDRFREGNPMFVDIAWHFGSD
PGNISSETSSSSVAAGCLDYCGMDTMLHITCCPYTKEQSIRHLEQSKALGLKNILALRGD
LPRQDENPVLYKYRALDLIRWIKEEYNDYFTIACAGYPAGHPEAPSYRADLLYLKAKVDA
GADFIISQIIFDGEVFKNFLRDCREIGITVPIIPGILPIQSYESIRRVAELSQLVIPDSI
LTSLEPIKNDDDAVRNFGIWHAVTLCRTLLSNGSATSIHLFTLNREASSREILQQLGLWP
RSPMRALPWRLFGESHPVRCKEDVRPIFWSMRPKSYVFRTRSINLVCLA
>A0A174I6V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides xylanisolvens|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A193SWR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cerasi|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A346PLV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natrarchaeobaculum sulfurireducens|TrEMBL
MSSEIQSTTTAAGVVTLLEEPRFELMPFESMDEQLDHLPEGAEVAITTSPTLGLEATVDW
TERASDRGFEVVPHIAARYVRDTAHLEAVAERLVDAGVTDIFVPGGDREEPAGEFTSASD
LLSTLEALEYEFDEVGITGYPEGHAFLDDETLAEAMAEKEPYATYIVTQLCYDPEAIVTW
IDEIRDRGVDLPVEVGIPGVMKYQRLLTISKKVGVGDSVRFLKKTSGILGFVRELVGSRG
TYVPDELIEELAPYAADPHYDLRGIHVYAFNQVPDLESWRSKTLTQHR
>A0A534KKF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MPAEVASRAIRAGSHLERILASGEFAVTAEIAPPASVDASEIRRHASLYRGTVDACNVTD
GQRALVRISSMAAATIALQEGVEPIMQMVSRDRNRIGLQSDLLGAAALGIRNVLCLWGDP
PTAGNEKDAKGVYDLSTEEMISTFRALRDTGVLRGGEKVDQAPKVFIGAAADPFRGSKEE
SFGKLRGKVTAGADFVQTQGVFDVDAFEEWMRLVRKEWLHDKVFILAGVIPLKSAKMARF
MVEKLGVVVPKQIVDRMERAPNPRSEGVSIAVRTIKALKKIEGVRGVHVMPIGWEEIVPA
IVKDAGLLPRPELAA
>A0A7I0B1U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus epidermidis|TrEMBL
MSHLLNQLKSNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKSFGLEHKVKEIHQAAVQIAKRAANEDTIILGTVGGFRGVRQEDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELTRIVTATRQKYDIPIIAQLTASNTNYLVDG
TEINAALKYVVECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDIAQELINEGVRLIGGCCGTTPEHIRYIKSAVKHLKPVKDKKVIPINKAS
SQKQTRVLKQNLTSKVKNGPTVIVELDTPKHLDTDTFFDNVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQRYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGINTDGDALKKHTNFNIAGAFDPNVRKLDGAIKR
LEKKVASGMSYFITQPVYSKEKIIQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSDDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A7X0YXX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEATEQIISQN
>E9DBB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccidioides posadasii (strain RMSCC 757 / Silveira)|TrEMBL
MEKISNKIAALPEDADYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT
ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPPRSDE
YNLDGEDDSNKEFTYAVDLVRYIRKKHSDYFCIGVAAYPEGHSDESHPGVQDPVRDLPYL
VEKTKAGADFIMTQLTYDLEAYKRFESMLRNHESGVFKTIPIIPGVMPIQSYPRLTRITK
LSHVRVPPEMLSRIEACKKDDEAVKKVGVDILSELVEGIKTIPGTGPRGLHFYTLNLEKS
VSFILERCNLIPPSSEASSDTDSDSVFASGNLQNGLGTAADKPPLISRRRASSLNSQPHN
RVIVDRADISSQSSITHEASAQGAGMPALNPPHRNTALQISEGMGALGREATWDDFPNGR
WGDARSPAFGEIDGYGPSLHVTANVARRLWGYPTTREDINNIFRQHVSGGLHAVPWSEGG
AAEETGGLSPETITIRPYLLSLIEKRGWWTLASQPAVSGVRSDHPIFGWGPPGEGFVFQK
AFVEFFCSKDDYRSHLKPLLQRYGHDEFAWFATNAAGDFESSTSSSIPVPTGPVDAVFDD
MDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWDEWRRIFPRGSPT
EKLLNRVKEDTWLVCVIGQRFGAGGDPGKDVMEEGKLLWKVLAGENVSLQS
>A0A290TX02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas piscicida|TrEMBL
MALTLQEKIIDPNQGVYLIGTTPPKIGTDPEQLKSIAAKLLGRLHEIEYDGVIIYDIQDE
SSRTQVPRPFPFKHTVDPCEYSQLIRELSHLDVITYKSVAQRDSEAFGDWLSSTKQQYGL
NNLVLVGSPSSQGDIKLPLSEAYKVLKHHQDDFFLGGVTIAERHASKRNEHERLIDKTEQ
GCQFFVSQAVYDAQATIDLITSYARTCKQQGQTPKRIILTFTPCGGEKTLQFMEWLGISV
PEATKWRMLDADNTLSESIRICRENLDQILKSCSHLDISLGLNIESLTNRKEEIDASINL
YRLLKATMELCLAEKQIA
>A0A536KX65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADLLARSRPSISFEFMAPRDESEVDVLERTVAALAGHAPDWVSVTYRVRTGEKTLEL
VTRIKRHYHIEAMAHLTCANTADRTRQILNWMEREGVANVLALRGDPPTTGEPFTPADPQ
LTHASDLIRLVRGSGYRFGIGAACSTEKHPESPDVEHEFQYLQLKVESGADFLITQLFFD
NRFYFDLVARARAAGIKVPIVPGLMPVPSRRSLALMTTMSGASVPAALQGAIDEASDDDA
IRALGVRHCIAQCAELLEAGVPGLHFYTFNRARAPIAILAALRGQQLIAS
>A0A535M8R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRITAMLAERRPVFSFEFFPPDTEVGTETLFRTIGELRELEPSFVSVTCRNHSRTRTLEL
VTRIRELTGIEPMAHYTCAGATLEELHSTLRSLREAGIDNVLALRGDPPQGETAFRSVDG
GLDHGSELASMIRREYDFCIGGACYPEGHTESVSLEEDLRHTVLKVESGVDFLITQLFFD
NAAYVDFIARARAAGITVPIVPGIMPITSVRQLSRFEGSLFGARVPPRLREALLRRSDDA
DAVVQLGVAWATLQCAELLAGGAPGIHFYTLNRSPATRAILSALLAARPWERKR
>A0A3T7R8N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATSDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A081CIG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudozyma antarctica|TrEMBL
MTNGIDTPSLPPKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMAD
LGPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPRDKIDTALKEAKEFG
CRNILALRGDPPAGQSEWEPHAAGFTQAQELVEYIRQQYGDYFAIAVAGFPEGHPEAVDG
PEKELERLKSKIDAGADFIFTQMFYDFDIFAKWVKDVRAAGITCPIIPGVMPIQTYGGFQ
RATARFGTLVPQYFHDALDPVKDDDQKVREIGTRLVGDMCKKIVGTGLGISGLHIYTMNL
EKGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRRDEKIRPIFWANRAKSYVNRTETWDEF
PNGRWGDARSPAYGDVDAYGVKLRYSNDEAKEMWGTPQSLDDVKALFQRFCAGQIKALPW
SETPVARETSVISEKLTRMNQLGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEF
FVSPEDLDALIARIEADVQITYHAVNAQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVE
SISFLAWKDEAYEIGRNWAKVYEPSSPSRKFLETMFDNYFLVNVVHNDFKAADAIFEPFL
SAAKGAEANGALSGLGASVSDAADKVSKAISSLANGGAANGHAAPQTPAPAT
>A0A7V7D144|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEYKAGSNLEKVLKAGHFAFTGECGPPTGANVEHLKEKAGHLKGCVDAVNVTDNQTAVV
RMSSWAASIILLQEGLEPNFQMVCRDRNRLAMQSDILGVYSHGIRNMLCLSGDHQKFGNH
PEAKNVFDIDSMQLIYTAKTMRDEGKFLNGQDVDVPPRLFIGAASNPFAEPFEFRVHRLA
KKIAAGADFVQTQCIYNMDKFRRFMKMAVDMGLHEKCYILAGVTPMKSVGMARYMGKSVP
GMDVPEPLINRLKGAGKGKVAEEGIKFALEQIEEFREMEGVAGVHLMAIEWEHKVPEIAE
RAGMLPRPVV
>A0A1D2J3Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccidioides brasiliensis|TrEMBL
MHIKDKLAYAEATGHPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPSEKVDAALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCEDQDDPELLMQHLKEKVDAGGTF
IITQMFYDVDNFLAWVKKCRDKGIKVPIIPGIMPIHTYAAFIRRSNWTKIQIPPGWLEAL
EPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVLDELGLIPSHETP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIQLWGKPKSLKELSEIFIRFLNGKLDRLPWSEGAVTEETDIIKRDLLD
LNSRGFLTINSQPAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNA
DLTYYCVNKTGELRTNTTDSPNAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHPASSPSRRLIQQVMDTWYLVNIVNNDFHRTHDIFDLFKNLKVKDLDLEVEPTDPAAE
FVGNIDHNGQSPEKLANGSAESKLQTITH
>A0A8D4LM70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mergibacter septicus|TrEMBL
MSYAKEINLLNQSVADLNGNINVSFEFFPPKNEKMEEILWDSIHRLEVLKPKFVSVTYGA
NSGERDRTHSIVKNIKQETGIEAAPHLTGIDASPDELRLIAQDYWQNGIRHIVALRGDEP
AGYAKKPFYAVDLVKLLREVADFDISVAAYPEVHPEAKSAQSDLIYLKQKVEAGASRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFIQLQKMAKLTNVKIPSWLSKLYDGL
EKDQTTRNLVGASVAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGLRPKV
>U0FHP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. P27|TrEMBL
MTFDPVRGRSSEGWATRTPSIVDRIASSTGSRIPFSVEFSPPRDADAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSTEELRAMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPEGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
YDTKYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVSAYDAEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGPDENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTPDTSVGTAQAV
>A0A068Z5W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia symbiotica|TrEMBL
MSFYHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIHRLSSLKPKFVSVTY
GANSGERERTHSIIKGIKDRTGLDAAPHLTCIDASPAQLRDIASDYWSSGIRHIVALRGD
LPPTDGGRPEMYATDLVTLLKDIGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANR
AITQFFFDVESYLRFRDRCVTAGIDVEIIPGMLPVSNFKQLQRFASLTNVRVPSWMTSMF
AGLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPMAAA
>A0A535K1I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLHRSRPTVSFEFMAPRDETEVDVLERTIAALAGHGPDWVSVTYRQRTGEKTLEL
VTRIKRQYHIEAMAHLTCANTADRTRQVLNWMEREGVANVLALRGDPAVSGEPFVPADPQ
LTHASDLISLVRRSGYRFGLGAACSTEKHPESPDLEHEFRYLQLKVESGADFLITQLFFD
NRFYFELVARARAAGITVPIVPGLMPVPSRRSLAVMTSMSGATVPAALQAKIDGAADDDA
IRALGVRHCIAQCAELLEAGVPGLHFYTFNRAKAPIEILAALRGQQLLAS
>A0A7C8ZCD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opuntia streptacantha|TrEMBL
MKVIDKIKAAEAENKTLFSFEFFPPKTDDGVENLFERMERMVAHGPSFCDITWGAGGSTA
DLTLDIANRMQNIVCVETMMHLTCTNMPVEKIDHALNTIKSNGLQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRGKYGDYFGITVAGYPEAHPDVIGPNGVASAEGYASDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPQEITDALEPIKDNEEAVRAYGIHLGTEMCKKILATGIKQLHLYTLNMEKSALSILLNL
GLIEESKIQRSLPWKRPANVNRVKEDVRPIFWANRPKSYITRTLGWEQYPQGRWGDSRNA
SYGALSDHQFMRPRARDKKLQAEWVVPLKSVEDVHELFKNYCLGKLKSNPWSELDGLQPE
TTIINEHLGNINMKGFLTINSQPAVNGERSDSPTVGWGGPGGYVYQKAYVEFFCSKDKLN
ALVEKCKAFTSITYMAVNKGGDDGISNVGNSDVNAVTWGVFPAKEIIQPTVVDPASFMVW
KDEAFEIWSRAWAQLYPDGDASRKLLEEVQNSYYLVSLVDNDYINGNLFSVFSDL
>A0A6C2YPG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tuwongella immobilis|TrEMBL
MNARGSEFLARLREEVLIGDGAIGTLLSDSEHRPDLRPERLNLLQPQLIREIHSAYVNAG
AQLLETNTFGANRTKLGSLNHPQEVAEINSVAAELAKSAAGDQAYVAGAVGPLRMTLTPD
QTVPHTDDEIREFFREPIVALANGGVDLLLLETFSDLRQLLLAIEVAKTVTDLPVIAQMT
FQEHGHTLTGVTVAQAMDSLVQAGADVIGSNCGRGVRCVISAVETMARSGDCLISAFPNA
GMPQFVDGRYRFAAPLPYMVDSAERMVQAGVNLVGGCCGTTPDTIRRMAERLRSRKPSVR
VRIEAAVPPAVVPAEPKGPIPAPPPAGSLLHQLDTADRYYGLPVEKRPGRRPMVVVELDP
PRGLNFGPIIKRAQQLRDMGVDAITVADNPVATLHMGNLGFSEIVQREADIPVILHMACR
DSNKLGIQSKLLEAHVRGMRTILALTGDPSKVGDTPGATSVYDLNSFDLIELIAKFNRGV
NDSELSIAGRTEYTIGVAFDPNGRNLKAVVDKLRRKVERGAHFAMTQPMYDVVRYHEMIA
ATQEFKTPIFVGIMPLLSERNAEYLHNEVPGIKLTDDARSRMKGFSGKEGRKMGNRIAME
LIDQMFPTADAFYLIPPQKFTEMAVELMAHIQSKIPAPEASGVSGA
>A0A6B3ZP77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKNIIGE
YNYAFELIEKIKANNNFGVSGACYPEGHIECESLNQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLSKTQQKNINVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>B2B2M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383)|TrEMBL
MHIREMLADAERTGAPSFSFEYFPPKTTQGVQNLYDRMERMNNFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYLGLETCMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPPREKEK
WEAAEGGFRYARDLVQHIRKSYHEHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDAGATF
IVTQMFYDADNFVRWVGKVRARGINVPIIPGIMPIATYASFLRRANHMNCKIPDEWMQRL
EPVKNDDVAVRDIGKTLVAELCRKILAAGIHHLHFYTMNLAQATRMVLEELDWMPSPDRP
VKQALPWKRSLGLGRQVEDVRPIFWRNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRQKWGEPTCIRDIANLFVRYLKKEIEYLPWSEAPVAEEADLIKDYLLD
LNKRGLITVNSQPAVNGVKSTHPVHGWGPSKGYVYQKAYLELLVSPEVYPEIKKRIENHP
DLTYHAVTKSGMLETNAPSDAPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGSDW
ARCYEADTPSRLLLEDIMKSWYLVNIVNNDFHQGETLYEVLNDLQEPNLDKVPQPPATNG
EAANGVEAST
>A0A6B4AED1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNEKNLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKNIIGE
YNYAFELIEKIKANNNWGVSGACYPEGHIECESLKQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLSKTQQKNINVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A6I1PJT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter hepaticus|TrEMBL
MCSFSFEIFPPRKDENIKNLDAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEK
YKIPSIVHLPCIHSSKEKITQILQQCKDRQLNKILALRGDVCNNLEKSKDFSYASDLISF
IQKYKDFEIYAACYPEKHNESKNFIEDIHYLKNKVDLGTNKLITQLFYDNDFFYTFKQNC
ALANINIPIYAGIMPITNKRQVLKITQLCGSKIPAKFTKILEKYENNTLALEDAGIAYAI
DQIIDLITSGVDGIHLYTMNKSRAAIKIYEAIKYLIKVS
>A0A2W1KFT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus|TrEMBL
MSLTALFKNKTVFSLEVVPPKKDSPKEAILPTLQQLQSINPDFISVTLGAGGSDHYTGTV
QIADLIQNQLNIPAVAHVPGLYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDF
NHANDLVAFVHQNRPDFSIASACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDN
QAFYDFQEKAEIAGIHVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSEEA
MREAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWNATKSVFDAANARTQTTIKHR
S
>A0A0G4J1H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plasmodiophora brassicae|TrEMBL
MVKVVDKINAMRQAGTPFYSFEYFPPKTEEGVDNLYQRLERMALLDPLFVDVTWGAGGVT
ADLTLEISRNAQRIIHLETMMHLTCTNMPADQVEKALDGARAAGIQNILALRGDPPREAE
KWEKCENGFGHAIDLVKFIRKTHGDYFGICVAGYPEGHVDSTEPDGDMLHLKAKVDAGAD
FIITQLFYDVDVFFDFVARAREIGIDCPIIPGIMPIQNYAAFRRMVSFCKTHVPPDIYAA
LEPIKDDDAAVKAYGVELGIDMCRRLLARGTPGVHFYTLNLERSVKLIMQGLGFIMPGKS
DRLPWPTSELPRRRSEDVRPIFWANRPESYMHRTLAWDEFPNGRWGDSRSPAFGDLSDYH
LCNGLSVKKAKDRRKIWGESPASVGDVVDVFKFYLTGKIGMLPWCDGAVQSETHGMLDVL
LRLNSRGYLTINSQPRVNGEPSSDKTVGWGAPNGYVYQKAYLEFFTSLDNLERVIALCKS
KYPLITYHAVNAAGKTFTNVPSAGAGEALPVNAVTWGVFPNSEVVQPTVVDPASFLTWKD
EAFGLWLSLWGSIYPRESASAALIQSFHDDYFLVNIVDNDYVRGDIVQFVDDLVDQQQVL
DARAEAGESQL
>A0A2W5JS21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter butzleri|TrEMBL
MFKTLIQKLQEDKYLTLETTPQHEPSMHNIIEKIKKFNLQDKIDGFSCTDNPLAKLRYNS
LFAALKLQQEFEKPVIATMTMRDRNKIALQSDLLGANDFDVRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGHPFKIEPKQIFPFAVVNSYAKNFSSLEKKMHLKI
QNGAIGIITQPIFDIENAQKLLESFDIAKENVEGDKRKSQLIFGIFPVTKLRTALFLSAQ
VPGIHVPQFWIDALEKAHSIGEEEEYKVGMELSSNLFKELNKLHPKIHLMTANRFDVANE
IIS
>A0A086YCQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haematobacter massiliensis|TrEMBL
MTPPRISFEFFPPQSLEASFRLWETVQALAPLNPAFVSVTYGAGGTTRKLTHEAVTTIHK
NYGLNVAAHLTCVDATREETLEIARAYAEAGVKEIVALRGDPPKGASGFTPHPEGFASSV
ELVEALAETGDFRLHVGAYPEPHPESPGTSSDVAWLRRKVAAGASSAITQFFFSPDIYFR
FRDAAVAAGVDVPIIPGIMPVNSWKGVRGFAARCGASVPASLDARFSAAVEAGREATFAV
EQCTELCEALIAGGVEDLHFYTLNRPQLTQQVCANLGIRPAAESAA
>A0A1C5A3J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora saelicesensis|TrEMBL
MALGLPSTLPNPQPAIGELIRERQPTFSFEFFPPKTEAGEQLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVVGRLAGVGVRNVLAVR
GDPPGNPGGEWIRHPEGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAQFVR
KCRAGAEFAVTQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQFSTIERSVQLSGAPF
PPALAARFERVADDPDAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARV
>A0A6J5ZIS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSQMREKLENTNEVVFTAEFPSLDGGGMAKVEKNAARLAPWFVGVNATDNPAAHAHASNT
ASAIAMKMHGIEPIMQIVCRDKNRLAIQADMMGAALHGIENISLLTGDDVTAGDEPESRR
VFDIDSTQAINIARIITTGKYLSGRKIDPAPDFYISAVENPSAPPFDYRIERALKKYRAG
AKYLQLQICYHPDRLEKFCAGVAKIAPDLKLIPTIVLVKSAKPMSFMHDKVPGIDIPQDS
LNRVTAAADQAEEAYQLTLELAKHALTLPSVRGLHVTDFRHDDSLDRFMYDLGQKPRN
>A0A708E515|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J7S5F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSDFPSHLAERFSTSERVFTVEFPSIDGGNLSAIKSRVDHLLPWFDAANATDSPAAHAHA
SNVAIAIALQNFGLEPILQVVCRDKNRIAIQSDIMGAALHGVRNIELLTGDDVTAGDEPE
ARRVFDVDSAQAIKIAATLKGGSYLSGRKFSDAPDLFIGAVENAAAPPLEYRAERVTKKV
NAGAKFFQLQICFHGDRLENFTQAVNASHPTLPLLPTIVLVKGARPLKFMNEKVAGIDIP
TEVIAQVEQASDPKEAAYQLARAQAEHALSLPGVRGLHFTDFCHDDSLVRLMRDLGVTPR
PTGSH
>A0A2K4X1F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>N8S6T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLNLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLESAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A6J6W0I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARSTFSFEFFPPKDAEGEARLWSAMDSLKSTAPDFISVTYGAGGSTRDRTIRITKEITA
RTKIPTVAHLTCVGSTRDQILEILTHYRDAGIKSIMALRGDPTGGPSTPWVSTPGGLNHA
DELVALAAEFGDFTIGVAAFPDGHPASHGDFDLDVNVLVRKEELGASFATTQFFFDASRW
SALVDRLRERGSNLPIIPGILPVGNVKQLVRMSELTGTPIPAKVLQRFQAVESDANAVRA
LGIEIATQLGQDLLAAGAPGLHFYTMNSSSATQEIYANLGIAR
>A0A6J7AFD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTKINELLKESRTVSFEFFPPKSDAEAAVLGETIRDLESLHPSFVSVTYRGGAESRQRTY
DLVTMMRRDTSLNPMAHLICVAHSRGELTEILEQYRDASIDNLMALGGDPPTEPDAKVGE
LQYALELVELARSVGDFSIGVAAHPAGHPRSETLNSDRDRLARKLEAADFGVTQFFFSIE
EYRSLVNDIADRGVTKPILPGIMPVTSLSSVPRMATMGAPVPAWAIERLESAESTGGADA
VREEGIALATELCAALLEEGAPGLHFYTLNRSKATREIALALGLNQK
>A0A3N2CMW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella terrigena|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A174JYS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus comes|TrEMBL
MRIIDKIKADGVHISFEVFPPKTDAGFESVLKATDGIAELTPSFISVTYGAGGGTSKNTV
KIASHIKNDLKIPALAHLTCVSSTKEEVHKVIGQLQKEGIENILALRGDIPQDGQFPLPG
QYSHACELIEDIKKMGDFCIGAACYPEGHVEMEHKKDDIRYLKEKVDCGVDFITTQMFFN
NDIFYNFLYRIREQGIMIPVLPGIMPITTKKQLARSCALSGTAVPQRFRAIVDYFGDDPA
AMKQAGIAYATDQIIDLIANGVRNIHVYSMNKPEVAAAIMQNLSEIVK
>A0A636X0U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella dublin|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3N9CXZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cenocepacia|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAATATRTICERLAM
>A0A5A7V2U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cucumis melo var. makuwa|TrEMBL
MKVIDKIRAATTGDGGRVVFSFEYFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGS
TADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKANGLQNVLALRGDPPHGQ
DKFVQIEGGFACALDLVKHIREKYGDYFGITVAGYPEAHPDVIGSNGVATTEGYQSDLAY
LKKKFDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCK
TKIPDEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHIYTLNMEKSALAILM
NLGLIEESKVSRSLPWRRPTNVFRVREDVRPIFWANRPRSYISRTIGWDQYPHGRWSDSR
NPSYGALTDYQFMRPRARDKKLLEEWALPLKSIEDVYEKFMKYCLGKLRSSPWSELEGLQ
AETRMISEQLGKINMKGFLSINSQPAVNGERSDSPSVGWGGPGGYVYQKAYIEFFCSREK
LDAIVDKCRALPSLTYMAVNKEGIWVSNVTQKDVNAVTWGVFPAKEIIQPTVVDPASFLV
WKDEAFEIWSRGWAALYPEGDWSRKLLDEIQSSYYLVSLVDNDYINSDLFAILEDF
>A0A6B2M646|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanipulchritudo coccoides|TrEMBL
MSKNRPITEFLSRNRPVISVEFFPPKDESGGEQIVAAAKEIREQIDPDFVSITYGAGGGT
RERTYRYASILKDEYGFEVMPHLTCVGSSREELLEIISAYQAAGFCNIMALRGDPPSGES
TFTPHPDGLPYAGDLVKLIRDNYSGFSIGVAGYPEVHPEATSAEDDLCHLKGKVDAGASF
ITTQLFYDNANFLEFVKRCQGAGIDIPIIPGLMPIRSAKQAKRFCQHIPAELEAALEAAG
DDPKKTREVGVDWTHRQIAGLMDAGIKAFHMYIMNRSGMAVEVIKRLRQSGRL
>A0A243JWI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar argentinensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQTGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1H3Y180|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio sp. ACV-2|TrEMBL
MLKDMFAKDSSLSFEVFPPKKDDEFENCYKVLDSLATLNPDFISVTYGAGGSRSKKTVDI
TSYIQNTLKLDAMAHMTCVGSSEEDILAVTKDLEAAGVSHVLALRGDKPRDMSDEQFEKR
IFPHATDLIQFLNKNTNLNISASCYPEKHPEAISMDSDIAFMKMKQDMGAKMFISQLFFD
NADFYRFVERASQAGITVPIVAGIMPITSAKQIGSTVTLAGSSVPKKLADICARYGEDAE
AMRAAGIEYAINQIQDLKRCGMGHIHIYCMNKAKMTAEICNAL
>A0A7X6CHJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcoleus sp. SU_5_3|TrEMBL
MNRFRTACITPREFIITAEVAPPKGGDMTHTLAMAELLKNRVHAINITDGSRAVLRMCPL
AVSAILVQHGIEPICQIACRDRNLIGLQADIMGAHALGIHNVLALTGDPVKAGDYPKAKS
VFDFESVRLLQAIQKMNNGIDWNDKPLTDGVTDLFAGAAVDPQCPSWSGLQSRFEKKLAA
GAQFFQSQLITDFELLDKFMNQIATGCNKPILAGIFLFKSAKNAEFIKKNVPGVHIPQET
IDRLAKAPQPLQEGIKIAAEQVKLAQQLCQGVHMMAVKREDLIPQILDLAGIDPFS
>A0A833P9Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bereziniae|TrEMBL
MSKLSQYFAQNQFCCLVEYLPTKNQVLPVRESLAGFPACMTLSDRVRSDEDIAPLIAAQA
YPDHIEKVLHYAGKGRDIDDFKLFLKQADSVGLRDILLLTVDKLKQHHDGQGQHARTRYL
ESVNAVMAAQQYGGFHIGMAFNPFKYTPAEQQAQYLKLHKKLNAGADYIITQLGFDLSAL
KQLQTFLAQEKYIQKTLACVMPLTLARAQFMVKHKVAGIVITPHMLEVLALDQVNQCSEN
AYKRCALQILICQHLGYAGVHLSACHKADEQMLLEQYIEQYRELNLSQCEMLWNQLWQLA
EGEQLRPKVAVKRIKSALNNKVKYQFLDLIHRTMFQSSFVKGIGTFIFNASFWNRKAAAK
VLLQTEYLSKHYLLGCESCGQCRLAETLYICPETCPKGLANGPCGGTDLDRCEFGDRECI
HSVKSRLAHDVDQIQLLKEQLIPTVPIEVRGTSSWKNWYKAE
>A0A7G7LDZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium NBWT11|TrEMBL
MAGPAPITQGHERRAPSRVSGTRRVGERAPSRPAPVPGPVQSVPSSGVTGTVRELLAEGR
PTWSFEFFPPKNAASEAQLWTALRELERLRPSFVSVTYGAGGSTREGTLAVTERIATDTT
MLPLAHLTAVDHSVAELRNVVARLAAAGVRNVMALRGDPPGLDPQADWVAHPQGLRYAAE
LVELVKDVGDFSVGVAAFPESHPRSPDAEADADMFVAKCRAGADFAITQMFFRVEDYLRL
RDRVAARGCDVPVLAGVMPVTSAKQIARIVQLSGQAFPADLAERFAAADGDTPEAKQAQR
DLGVEVATEMCRELLAEGVPGIHFITMNRSTATREVYAALAELAPTA
>A0A7C7YJ21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MNIVDLYRNGDPVMSFEFFPPKTERGYQSLFETIRDLGELAPGFVSVTMGAGGSTRNQTV
DLVIRIERELGLTAMAHLPCLGSESSEIAQILDDLTAGGIQNVLALRGDPPRDAADFRHP
DSGFDYANELTAFIAERGGFTIGGGCHPEMHPEAESPEVDLAQLKKKVEAGSQFLISQLF
FDNTKFFDFVERARAVGIQVPIVPGIMPITSVSGIRRMASLGGGTIPAELNATLSLNENG
GTGTNTGTNNTNDAILEIGIEWATLQCRELIEGGVPGIHFYTLNRSSATRRIHHALREMG
LVQ
>A0A3P0MU54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Bp9031|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDNLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAASATRTICERLSM
>E2CPX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium sp. TrichSKD4|TrEMBL
MSDHRLTPEGRLAASTEMSPKQVVEKSELLEFIPKGTRVYVTDLGNASEDMIVSAAKTLS
DRGYTPVPHMAARRYQSVDAFETRITRLTQEAGVTDVLAIAGEADKAGPLTSSVALLETG
LFDKLGIKTIAVAGHPEGAPEIKPDVIKSFLMRKHELAAESDAQFILATQFGFDPHKVSQ
WLDEIAGWGNQFPVHIGIAGPAKMTTLIKYAAFAGVENSLNFLKKRGGSVVSMLAGYDPE
TMVGPLETRVEARPDTQLQQLHVYPFGGIQKTGEWLANRRSWSFRSTDTSSLRA
>A0A2E4X025|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MRVIEHLDRAKEPLISFEIIPPRRGGDLKSLLGLIDDLVAHRPPFIDITSHPAVLSYEEG
PDGIRKVIKRKRPGTLGVCALIQHKYNVDAVPHVLCRGFTREETEDFLIELHYLGIDNVL
IIRGDDNGYNKPVKEGRTANRFAVDLVSQVGDMNQGQFLEPYLQALPTNFCVGVAGYPEK
HMEAANLDMDVRRLREKVEAGADYIVTQMFFENAHYFRFVEKCRDHGITVPIIPGLKVMT
VKKHLTSLPRIFNCEIPTALADEVETADKDKVLEIGAEWTANQAQELXDSGVPSVHFYVM
QSSKAINKVLKRLKR
>F0K301|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus delbrueckii subsp. bulgaricus (strain 2038)|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADYLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILNRYQNSKEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNNADIAERIWNATKSVFDAANARTRTTIKHRS
>A0A0L0V3W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia striiformis f. sp. tritici PST-78|TrEMBL
MANLKPSCAHVTWGASGSTSDTSLEIAAMVQDQLSIPACLHLTCTNIQRSHLDQTLSQAK
ESGIVNILALRGDPPRGTENWIPTDQQFQHAIDLVKYIRKEHQTHFCIGVAAYPEGTNDF
DQDQELDYLKQKVDAGADFIVTQLFYDVDFFLNWVKACRKLGINVPIIPGIMPIQSYEGF
RRLTALCKTKIPDSIHAKLIPIKGDDQAVRDFGVELSMQMIKLLRVNGFKSFHLCTLNLE
RSITRLVSQLGWAPGRGNKQCQSLLGPGAKMGTADIVQGGLSVGWDEFPNGRFGDQRSPA
FGLREGYSSSLTSAFSHLTTDVHALWGTPTSLEDITNIFCAFTQGKLHSTPWSEEPLALE
TTSITPFLAKLNQNGWWTVGSQPAIDGVDSLDSVVGFGPEGGRVYQKAFVEFFIPKSHLE
GLLSAVGEYNKDHPEGVAQLRYYAGNCNQDQIRTNMALGETNAVTWGVFRGAEVVTTTLI
EAQSFKTWKKQAFDIWNDWAESFESGSANQRLLNEIEDSYWLCSMINHDFKQADHLWSFL
INHQQRLLAEQS
>A0A0F8VF55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus rambellii|TrEMBL
MHIKEKLAQNEAAGRIGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPRERVDAALQSAYKAGCTNILALRGDPPLYSRK
YGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSSFVVTQMFYDTDHFINWVKKCRD
RGINVPIIPGIMPIQTYAAFIRRANWTKARIPPDWLEALEPVKNDDAAVKEIGKRLIADM
CRRLIAAGINHLHFYTMNLAQATQLVLDDLKLTPTPETPLQRALPWRPSLGLNRREEDVR
PIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDAYGIGIKGTNDQNIKLWGEPKS
LRDLADIFVRFMEGKLERLPWSESPISAEATSIKENLVELNKRGLLTINSQPAVNGVKSS
HPVYGWGPKNGFVYQKAYLELLLPPYLINDLIARIEANEDLTYHAVSKSGELLTNTRDSP
NALTWGIFAGREIVQPTIVETISFLAWKDEAYQLGEDWAKCHDAASPSRKLIQGVMDNWY
LVNIVNNDFHNTYNLFELFNGLNVKDLDVEVAGEIVEPKALQNGTTNGTTNGATPEPVAQ
N
>A0A1X9T1P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. RM8964|TrEMBL
MLKTKIKQGKSGIVLYGLTPPKISLSHDEAKEIALRQLSRLDGIKIDGLVIYDLQDESNR
NSSNRTFEFVRTIKPEIYAKDYLQNRYEAVIYKAVGNYNEAEFKEFLQTHSDAISIFVGA
SSAIDTPKLSLNDAYKMKKEIANDLTLGGICIPERHTKKQDEDLRVASKRVKGCEFFITQ
AVYDIETAKKFLDDFAALGIKNTPIIFTFTPCGNEKTYEFMQWLGISVSNLSKNRIFDSD
DALESSVKLSLDMFEFLYKYGTAKGVSVGANIESISTRKVEIDASIRLLKGIIAIVEKNS
LENTKSKIQSASRFDE
>W3RKU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afipia sp. P52-10|TrEMBL
MSDSANQGQQAAGGRKLPKISFEFFPPKTEEMEQTLWETIKRLAPLEPSFVSVTYGAGGS
TRERTHATIARILKETSLTPAAHLTCVDASRGEIDEVVARYHETGVRHIVALRGDPSAGI
GAAYKAHPDGYQSSAALVAGIKKRYPDIEVSVSAYPEKHPESASLDADIDVLKAKVDAGA
ARAITQFFFDNDLYNRYVDRVRARGIAIPIVPGILPVQNFKLAKNFATRAGASVPAWLSE
KFDGLDDDPETRKLIAAAVAAGQVQKLNKHGVDNFHFYTMNRADLVFAISHLLGFRANSA
QKAA
>E2CKI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium sp. TrichSKD4|TrEMBL
MTSTLPIRRSRQQLQGPLNASFEFFPPKNEKMAESLWNTVERLAPLNPEFVSVTYGAGGS
TRERTHKTVERILKEARLDTAAHLTCVAASREEIDAIVKDYWQLGVRRIVALRGDPVEGI
GATYKPHPEGYAYASDLVEGIKKIADFDVSVSGYPERHPESSGWDMEIENLKRKVDAGAD
RIVTQYFFDNDLFDAYRERLAIAGITIPVIPGILPIHNFEQTMVFSAKCGASIPDWVARR
FTGLQNDPETRKLVGAGIACEQVMDLVDRGVEDFHFYTMNRADLTYAICRMLGMGIESEN
KVAA
>A0A2R6MKH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon SW_12_67_38|TrEMBL
MSVARSAAAMDGATDLLTDLRFELMPFDSFAGQMDHLPDGATIAITTSPQLGLDATIEWA
EKAANRGFEVSPHIAARYVRDEEHLEAIASRLTDAGVTDIFVPGGDREEPAGEFDSAYDL
LTALDDLDYEFEEVGITGYPEGHEFLDEATLAESMERKAPYATYIVTQLCYDPDAVVSWI
EEVRDRGVDLPVEIGIPGVMKYQRLLKISQKVGVGDSVRFLKKTTGILGFVRQLVGSRGK
YTPDDLIDGLAPYADDPHYDIQGLHIYTFNQTSDTESWRYGRLEE
>A0A8J3I070|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ktedonospora formicarum|TrEMBL
MRVALEAIRGLTDVPIVALMSFDEDNTVSSGEEPLTVAQTMSELGADVVGVNCALGPAGT
YNVIESMSSEDPKRFLLAAQPNAGLPKRVGNRFIYVSTPDYFADYTRRFLESGVRLIGGC
CGTTPQHIAAMRKVLAEYAPNVISEAPPTKRPAHLEVVYERDTETTGNPKARRTHLAQQL
QAGRFVVSAEMRPPRSVKFTRFLQNAEYLRDVGVDTINITDNAMAHVRMSNVAAARLIQQ
HVGVETIIHFTPRDRNLMAVQSDLVGAHATDLRNILAVTGDPPTYGDFPNATGIWDVDSI
GLIAILNNLNQGLDGRGRRLGTPGSFFIGCAATPPAADIELDLERLHRKIEAGANYIMTQ
PVYDPETLITYFERYTRNYGPVPIPILVGLQPLHSYQQAEKFHNEVPGIIIPEAVRERLR
LAGDQASAVSLEIIKGLFDAILPHVQGAYIMPLDRYTLVGDLLPYIRERTAHFGATDENA
ASQ
>A0A1G9VYW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. OK048|TrEMBL
MTFLEKLKNQILIADGAMGTLLYSFGTDSCFEELNLSHPEKIQEIHKAYIDAGADVIQTN
TYAANYLKLQRYGLEDSVKEINAGAVQNAKKAAGGQAYVLGTIGGIRGIKSSTVTIEEIK
RSFREQFYCLLLEGVDGFLFETFYDLEELETVLTIARKETKLPLIAQVSLQEPGILQDRT
PINEALKRLENLGADVLGLNCRLGPHHMLETLEQIELPSHAFLSAYPNASLPAYTDGKFH
YEGDADYFRKSAQAFRNEGVRLIGGCCGTTPEHIRAIASELKNSAPVTEKVVKFKAKKMA
IESHAAKRDVQPLEELVKERPSVIVELDPPRKLDTSKFFEGAKALKEAGIDAITLADNSL
AQVRISNESLGYLVKKELGMRPLIHIACRDRNIIGLQSHLMGLHTLGMHDVLAITGDPAR
VGDFPGASSVYDVSSFELIHMIKQLNEGLSFSGKDLGQKTAFSIAGAFNPNVRSVEKAVK
RLEKKIQFGADYFISQPVFSEEKLIEVYENTKHLNAPIYIGLMPLTGSRNAEFLHNEVPG
IKISQSIRDRMAALSDHPLQAAREGIEITKSLIDAALDLFNGIYLITPFLRYELTTELAI
YARQRASQVRGNSYVESSIK
>A0A2U9NZD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces actuosus|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWETDVRHFVD
KCRAGADYAITQMFFHPEPYLRLRDKVVAAGCDTPVIPEILPVTSIKMLERLPKLSTAAF
PDSLKERILTAKDDPSAVRSIGIEFATEFCARLLAEGVPGLHFITLNSSTATLEIYENLG
LHHPPQA
>A0A1A5HR66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium loti|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVGRILNETSLTPAAHMTCVDAARHQVDAVIQEFAAMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A2M9ZWZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira neocaledonica|TrEMBL
MKKILEIYKTAKTPVYSFEFFPPKTPEGETKLFEAVEELSKVDPGYITVTYGAGGSTRDK
TIRITSELAKKFALPAAAHFTCVGGNKEEIRVILKQIRESGIENLMALRGDPPKGEEAFK
KVEGGFGYASELISFIKEEGFDFCMGAACYPEKHPEAASLESDVDNLKRKVDSGASYLVS
QLFFKNSNFESFLDLIRKKGINVPVIPGIMPITSFTQIERFKAMAACEFPEKLVSDLEEV
KDQPEEFYKRSINFSVNQCRELVKLGAPGIHLYTLNQSPASLDIVRELKN
>R6ABC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. CAG:5226|TrEMBL
MTTGNKQHTAFSFEVLPPLRGKGMESIYRTIDNLMQFNPVCINITTHRAETIYSEMPNGA
YQKLSVRNRPGTVAIAAAIKERYHVHTVPHIICSGFSAAEIESELMDLSYLGITELLLLR
GDRAKDENRFIPSPGGHAHAIELCRQVNDFNEGKLLGGVVTNPLETPFVYGVAGYPEKHD
EAMNLDTDIEHLKAKVKAGAKQIVTQMFFDNSKYFAFVERLRREGIDVPVVPGLKPLTTL
NHCTMLPKTFHIDFPQELAREFEKCRSNADVKELGVEWGIQQVRELKAAGVPAIHFYTMN
AAFSTERIASATF
>A0A117N386|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium loti|TrEMBL
MTVRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQSARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVADRLDHLLHDELTETQVDMVK
TAH
>A0A7S2W8U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|labyrinthulid quahog parasite QPX|TrEMBL
MTGLIAEMSTQPAPKICDLIAAKRNEPWIAFEYFPPKTEQGVENLKKRLARMAEFNPLYV
DFTWGAGGSTSDLTLELSQKAQEDNKLVSNMHLTCTNMPKDKLDNALKVSQQVGIRNILA
LRGDPPVGQKDFEPVDSGFSCALDLVKYIRQETGDVFCVTVAGYPEGHPNRIKKVDNPEL
LSETERSRAVTMEDGSLHVCSDKDFKEELDYLKEKVDAGANAVVSQMFYDVQCFINFKNA
CKAHGINVPIIPGIMCITNYNGYKRMVGFCKTRVPEAIKAKLEEIKDDKAAVEEFGIHYG
TETCKTLLANGVNGLHFYTLNLDKVVGGILENLKL
>A0A8G0KCF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. animalis|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSIEKPDYISVTYGAGGNTKGRTV
EIADRIKRQNGLESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEKGD
FNCARELIEYIHKKKGDKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRHE
>A0A6J1ZIU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinonyx jubatus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEASSGRFSVPPSISISHLTLPLRVLAACPLTLLPSTP
CSRNPAMVNEPRGDGGPTSRSEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRMES
GDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIAST
AVNYCGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYA
ADLVRHIRSEFGDYFDVCVAGVPCPGLSVPTPSAGRRTCVPSSGPPDQRVTSTAPRSGMS
SPTAAAFGELKDYYLFYLTSKSPREELLKMWGEELTGEESVFEVFACYLSGEPNQNGYKV
TCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQK
AYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGEKITNAPELQPNAVTWGIFPGREII
QPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDN
CLWQVVEDTFELLNRPGPEQETETL
>A0A3R7JP52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula sp. Atlit-120R|TrEMBL
MALGTHAVSNSQGVQTLLTSARFELMPFESFDEEITHLPDDATIAITTSPQLGIEKTVEK
TEQAAAMGYDVVPHVAARYVEDRAQLEAITERLDQAGITDIFVPGGDREEPAGEFESALD
LLEALADTEYDFEEVGITGYPEGHDFIDDETLAESMARKAPYATYIVTQLCYDPDAVLEW
VEEIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDNDYNIRGIHIYTFNQTPDTEKWRHKRLDS
>A0A839SRP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limibacillus halophilus|TrEMBL
MSLEKTIADFLTDFTIETTPGSAAKIPDYREHLREGTKVAVTFLPGSDFADTVKTSKKLK
DEGMVPMPHFAARSIPSKDAFADYLKRLQDDVGIAHVVALAGAVEKPLGPYESSMALLET
GLFEEHGIQTIGIAGHPEGSPDISDSDLASALAWKNTYARSSSAKLYIVTQFCFEAEPIL
AWEKRIRNAGNALPIHIGLPGLATIKTLVNHARACGIGPSMNFLVRQARNVAKLMTVNAP
DKLTLDLAQHVASNPECLINKVHMYPLGGLRKSAAWSYAVVEGDITLKSGNKGFKVNRDI
D
>I9AEI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter siderophilus SR4|TrEMBL
MLKNENLCTKLKKRKFVVTAEISTPKGVDITKTIEEARKLKGIVDALNITDCPMANMRMS
PIAVAHLLQDHLNIEAIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDDPSRGDTPQ
AKGVYDVDSVGLLKIISAFNRGYDYNGNKLDSPTEFCAGTTANPNDLRDEALEKLKVKIE
AGAEFIQTQPVYDEEILFKFIEKIKNFNVPLLIGILPLKSYKMAVNLNEKVPGIDIPEKV
LERLKDGGREEGINIAVEFIKRIRSEVAGIHIMPLGSTNVVLEIISRVDDLVCDFAENNV
QMN
>R5ULZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes finegoldii CAG:68|TrEMBL
MNVLDIINTAIAEHRTRFAFELLPPLKGDGMGGVFAAIDRLIGFDPAYINVTFHREGIKQ
SVRPDGGIDWHVVRRRPGTVGISAAIQKKYGVEVVPHLICGGQSKYDIEDALIDLDFLGL
HNVLALRGDKSQNEKFFMPHPQGHSHAVDLVRQIAAMNRGEFVDGEVEECHHSKFSIGVA
GYPEGHEESPSPEADIAALKAKIDAGAGYIVTQLFYDNARFFDFVRRCRKAGIAVPIIPG
IKPLSTLRHLTLLPQTFGCRIPEELEREVLRHREDPKAIREVGTEWAVAQSRELKQAGVP
VLHYYPMGKADNIIKIAKAIF
>A0A260WBZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 14-2470-1a|TrEMBL
MDRLRSDGAARIPFSVEFSPPRDEAGEARLWRAVREFEQLQPAFVSMTYGAGGSTRDRTV
RVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRGISNILVLRGDPPGDPLGDWEK
HPDGVEYADELVTLVRELGDFHVGVASFPEGHYRALNLEQDTQVLVNKLRAGAEYSITQM
FFDVDDYLRLRDRVAAFDPEQGAKPIVPEIMPITSLRTVRRALALSGSALPKALDDRFTA
AAGTGREEDRAAVREVGIELATQIGERLIAEGAPALHFITLNFAKATREVLTNLGLCAAR
V
>A0A373SAQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF25-19|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A1Q2GVF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas aliena|TrEMBL
MALSLKEKIVDTKQGVYLIGTTPPKIGTDKTQLKIIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQARPFAFKQTVDPREYSHLLRNLSSQDVITYKSVAQRGVGEFKDWLSETKNDYDL
QNVVLVGSPSSIGDIKLSLPDAYKALAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGITPQRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKLIAQGC
>G2SM80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ligilactobacillus ruminis (strain ATCC 27782 / RF3)|TrEMBL
MPNQAVDSLITQMFFDNESFYRFRECCELADINTPIVAGIHLYTMNDAETAKYIWQATRS
LFENGRKVH
>A0A1C7LBY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia sp. JD2|TrEMBL
MSFPISFEFFPTKTPEGAAKHVQVRKNLYARKPQFCSVTYGAGGSTQAGTFNMVRDIQSE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPHSDLEAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A7C0YCV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MIKKITDIFKEKDRTFSFEFFPPKTPKGIENLYRAAEELNRLGPDFVSVTYGAGGSTRGA
TMDICVEIQKRFDITVMHHLTCVGHSRQELEAVISQLKDNNIKNILALRGDPPKDVENQE
PAPDGLEYCY
>A0A522UNP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MKSGSNLEKVILSGQPAVTAELGPPMSADPHEVIKKANQLKGFCDAANITDCQTAVVRIS
SIAAAALALREGLEPVMQMTCRDRNRIAIQADLLGAAALGLKNCLCLAGDHQVFSSAGRL
KGHPGAKNVYDVDTCQLVGILKKMRDEGLQEGGDKLEVAPKFFIGASWTPMGDPIDFRPM
NLMKKVNAGADFIQTQGIYDIELFRAQMEKIRNMGLHERTAILGGIIVPRSAMMLKYMDS
SVAGVTVPKPLIDRLNKAKEAAGDDKKKARELQEAEGLKITIELIHQVLETPGVKGVHIQ
AIEWESAIEGIVKAAGLYPRPTFTD
>A0A8J6VGS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichocoleus sp. FACHB-69|TrEMBL
MPTIENSMLFKSFRSAAEAGEFLITAEVAPPKGGNPVHMVEMAQTLKGRVHAVNITDGSR
AVLRMCPMAASVILLQHGIEPICQMACRDRNRIGLQGDLMGAHALGIRNILALTGDPVKA
GDHTDAKSVFDLESVRLLGLIKKMNLGFDWNDKPLTDGATDLFAGAAVDPQLASWSGLQS
RFERKLEAGAQYFQSQLICDFDRLEKFMDKIAAGCGKPIMAGIFLLKSAKNAEFINRCVP
GVNIPQDIIDRLAAADDPLQEGMAIAAEQVKLASQLCQGVHMMAVKREDLIPEILDMAGI
PPLNQLVSAGTEDERTNNKATADSVAL
>A0A6J4LLB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Gemmatimonadaceae bacterium|TrEMBL
DHPRRAARRPARPRPRHAVRRRDGDRAVRARGVHQPVLRRALAARAGAGARGAPGVRRRG
RRGDRDEHLRREPGQARAVRPRGPGARDQPRGRARRPRGGRGARARRGRGRAARRAARAV
RADEHGGRARAVRRADRRARGGRGRPPGVGDVRRPAGDRAGDRGGARGGAGAPRGRAGDD
RQRLHDPVRRDARGRGARARRVGGRRRRPQLLGGAADDPRRDRADGARHEAQARRAAERR
DAARGGRALDVHGEPGVHGHLRAPPRARRRQRGRRLLRDDARAHQDDGVVAAGGAGDGEG
GWEGGGGRWERAGRRASRRGAAHRRQGPRPLQRPTSDLHPGRRPRAIPRALAAGGEDRAR
GVRDLGGDRAAAGGGRDEAARRRRHAPRRRGGRDQRARRAARAEPDGGDHDEPAHRAARR
DRDGDALRLPRPQPARHAERPAGRVGDGAAQHPADHGRPAEDGPLPRRDGRLRHRRDRAH
EPRAQPEPRDGPGRERDRRADALRDRRGGEPGGGGPGPRAAPLRVQGGRRGRVRDHAAGV
RRRAAGAVPRDDRARAHPGGGRRLAAGVGAERRVPRERGAGRDRARGHDRPDAPRERPLE
GARRGRGRRHRARAAGAGARERAGRAGERAVRQGGPGAPAVRRAHGGAV
>A0A3M2AQ57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MHISDILKRTHPAFSFEFFPPKTEAASKELFHTIQQLVPLRPAYVSVTYGAGGSTRELTH
DLVVRLQRETNLTIVSHLTCVGSTQEEIYQILKKYEASGIENIMALRGDPPKSPIRPIPA
HQGFRYAADLVAFIKKHFPHMGIGIAGFPEGHPETPNRLVEIEHLKRKVDAGADYICTQL
FFDNRDFYDFCERCEIAGITIPIIAGIMPITSRKSMIRMSELALGARFPAKLLRAISRAE
TDEYVEKVGIHWATEQILDLLDHNVNGIHLYTLNKSKATLQIYDALGIQHFDALNHHRRT
L
>F3NRH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseoaurantiacus M045|TrEMBL
MRDMLAAGKTVSSFEFWAPKTEKGERNLWNALRRVEAVAPDFVSVTYGAGGSTRSGTVRA
TERIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMAEWVAHP
EGLTYAAELVHLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVDKCRAGADYAITQMFF
EPEAYLRLRDRVAAAHCETPVIPEVMPVTSVKMLERLPQLSNAVFPGELKDRILAAQGDP
AAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLGLHHTRQA
>A0A433SJJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elysia chlorotica|TrEMBL
SPNPTEFRPIQRRFSPPSFDRQNSLTESEKNGSLSRPECESSSASSSRANSPVLYNSRKY
VPVIDRILKRQASGTPFFSLEFFPPRTDSGASDLMAIFDRLARGRPLFCDMTWHPKGDPS
NTNKPTSSTSMAGNMLNYAGIETMLHMTCVGLNTEQMKENLYKAKNLGIRSILALRGDLP
DGAEEWQKTEGGLDYAVDLVRLIKEEFGDYFVICVAGYPDGHPECKSYWEDIQHLKDKVD
AGADLIITQLFFKNDTFLKYVSDCRKVGITVPILPWNSMNRSYPIQGYKSLSNMAKLSKL
EVPKEILDAIEPIKTNDIAIRQYGIFKAVEICRELLNSGMVPGIHFYTLNREKAVTQVLK
ELGLWSEKIQRPLPWKQTANHNRIEEEVRPIFWRCRPNSYVLRTSEWNEFPNGRWGDSRA
ASFNDLQTYHLFYLKSKSPKAELLKMWGETLTSERDVWKVFVNYLSGAQNEQGVKVTRVP
WDDDAIEPETSLIAERLASINSRGVLTINSQPRVNAAPSTDLKVGWGSPGGYIFQKGEAD
YTNCDEFQPIAVTWGVFPGKEIIQPTVVDPEAFKTWKDEAFALWLEAWGHIYSPDSESYK
VIKNIHDGYYLVNLVDNDFPKESVLWDILEEMLALNASRQETESAAVSS
>A0A521SMZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MRIPAYFESGQPIFSFEFFPPKTDEGVEHLFQTIGELKALAPAFVSVTYGAGGSSRQRTV
ELVRRIKGEHGIEAMAHLTCVGSDREAIDRTLCQLKEAGIENVLALRGDPPKGEGTFSRP
ADGFSYAYELVGYIRNHHDGSFSLGGACYPEGHVECRDLDKDLAHLKKKVETGLDFIITQ
LFFDNRHYFEFVKRARAIGIQIPILPGIMPITNVGQVKRFTEMCGVSIPASLLSALEPVQ
EDPEAVMRIGIEHAAAQCRELLSRGAPGIHFFTLNKSPATRAILESLSDLR
>A0A1G1G3Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium RBG_13_39_12|TrEMBL
MTFSESLNSGKFVVTAEVGPPKGTDIKEMLHHMELLKGKVDAANVTDNQSAVMRICSLAV
CRLLIEHGLEPILQMTCRDRNRIGIQSDLLGASILGVKNVLCMTGDHVSAGDHKDAKPVY
DVESVQLLRIVECLNNGKDMSGNDLKGATDFFQGAVVTPETNPIEPQLFKFEKKVKAGAK
FFQTQAIYDIEKFKEFMKFARTLPAKILAGFVILKSAGMANFLNKNVPGIRVPQELIDEL
KAAGKEKALETGLNIAARHIKQLREEAICDGVHIMAIGMEDKVPVIMEKAGLL
>A0A533Z1P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MDLSGSRRRRTHDHRHVVTEYAGVCAARGWQGGALTVPVRRFKDALQSGEFVTTVEYNPP
KGTDVAALLDNAKSLVGKVQGVNVTDNTAAILRAGSMSICRLLFEMGHDPVMQMTCRDRN
RLAIQSDLLSAHILGIRNLLCLTGDYPTVGDHKEAKPVYDLDSIDVMQIIKSLNEGKDMA
GHKLHGTTDLYVGAAVTPEMDPPGPMLAKFEAKVNAGTRFFQTQAFYDVEKFKTFMNSVR
KFPVKVLAGILVLRSAKMAEFMNANIPGVEVPEAIIAELRAVGDEKALDVGVQIAVRMIK
AVRDHCDGVHIMAIKAVDRLPEILKKAELA
>A0A521K247|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSGPRRLKEVLDRGEFAVTVEYNPPKGTNIAALLANAKALVGRVHGVNVTDNTAAVMRAS
SLSICRMLYEMGHDPVMQMTCRDRNRLGMQSDLLGAHILGIRNILCLTGDYPTVGDHKDA
KPVYDLDSVQVMQLVQKLNQGQDLAGNKLDGTTDYMIGAAVTPEMDPQGPMLAKFAAKVN
AGAQFFQTQAIYHPESFGSFMGAVRKFKVKVLAGILLLRSAKMAEFMNANIPGVSVPEDM
IAELREAGDKKALDVGVEIAVRTIKAVRPHCDGVHIMAIKAVDRLPEILTKAGLG
>A0A2T2UKY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium SW_7_64_58|TrEMBL
MKVTEHFDQASEPLISYEIIPPKRGGSADQILRVVEELMPFDPPFIDVTSHSAEVEYKQQ
DDGTWHRCVKRKRPGTIGLCAAIEARFGIDTVPHLLCKGFTREETEDALIELNYLGVENV
LAIRGDDKGYEKSISGNRSRNEQAVDLVRQIQDMNQGTYLEDMMNAEPTDFCVGVGGYPE
THFEAPNLAWDIMRLKEKVDAGADYIVTQMFFDNEYFFNFVDKCREVGIDVPIVPGIKIL
KRKRHLRLLPKYFHTEIPEELAAEVDAADPDDVENIGVDWAIRQTRELMEAGVPCMHFYI
MSSADTVKKVVEPLHEMA
>T0QC88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus temperata subsp. temperata M1021|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSIGRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWNNGIRHIVALRGD
LPDNSEKPKMYGADLVELLKKEADFDISVAAYPEVHPEAKNSQADLICLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQLKRFATMTNVRIPSWMTRMFE
GLDDDPESSNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A3M9LP23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus sp. RSK|TrEMBL
MPSAFKEKLLSDEFVITSEISPPKGVDVSSAFEEAGLVRDYVDAFNITDNQRAVMRMSPL
AMGHMLKEQGLDIIMQFTCRDRNRLALQSDLLGAYAMGMENVCIMSGDYPTKGDNPGAKP
VYDLDSVQLLGAMNRLEEGFDIAGNPLESSPSFTKGAVCNTEPDQPLQLMKLEKKARMGI
DFFQTQAVYDIGHFETFMESISHLEIPVLAGLIPLKSAHMARFMNEKIPGIQVGDELIAR
MESSTDPAEEGLLICAEQVRELKKVCRGIHLMPIGHYRHITALFEMAGLHEKN
>A0A4R1L7J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidipila rosea|TrEMBL
MTTRAGRRLQEIFNTRPVLCDGAMGTSLYARGVFINRCYDELNLTEPELVRSIHEEYLQA
GAEIIETNTFGANRFRLLRYGLENKVEEMNLAGARIARQAVEHLAEKQAGQAWVAGSVGP
LGVHLEPLGKTSLQEAREAFAEQIRGLVAGGVDLLIIETMPALNEAEQALKAAKETAPDL
PVMVMVTVDEEVNCLDGSSPETAAARLTAWGADAIGCNCSTGPANVLSAIECMAAATDLP
LVAMPNAGMPRAIEGRNIYLCSPEYMASFAKKFLKSGVQFIGGCCGTTPNHIRAMKSALR
AAEAQKTAPARMAREPIVTETPPAPLEERSRLGKLIQEGSFVTMVEIVPPKGIDCRKELA
GARLLAELGVDIINVPDSPRASARMSGQSLCIQIQQQTGIETVLHYTCRDRNVLSIQSDL
LGASSIGLKNILCLTGDPPKLGNYPDATAVFDVDAIGLVNIVNRLNYGLDIGGNPIGEST
GFTIAVAANPGVPDIDNEVRRFAYKVEAGAEYAITQPVFDLRLLESFLKRIEGFRIPVIA
GIWPLTSLRNAEFMKNDLRVSMPDEIMLRMQQVGSPEEARAEGIRIAQEMLAATRSMVQG
VQVSAPFGRYTAAAEVIQAVLPKRVATV
>A0A812MAN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiodinium sp. KB8|TrEMBL
MASAAAEAAAPSGAGSRPAAPAGGVRMVEGTTIPCGPPGNKIIDRIREVHAAGGTTVSLE
FFPAKEEPLAAWLASSRLPDTKRNCREAERRPPAAASRSTIAHNARVLALAPLATGRRRA
WGEGVARRQTRAERAKGVLARFARRPQPQSVLRCVAVGFLPPQTSKGVDNLLARIEGMTF
RLRPTFVTLTWRSAFTDELLWLRIGAHVQREFGIDVLLHLTCHLPVEDLKRVLRRCREAG
IRNILALRGDPPIGQDKWTPCEGGLRNAVELVRLIREEHGDYFCVAVAAYPEAHTECWNN
PDLPPSEKARDLDLRRLKDKVDAGSDFIITQFFYDVDRYLEFDRRCKAAGITAEMLPGYM
PIQNYRGFAKFTKWCKTAVPPELMEAVREVRDNDEAVKDLGVDDAVAACRRILAAGGRCL
HFYTMNLSASISAVLDQLDLVPKAHEREAPWAASGPARSKDEVRPIFWSNRAASYLARTS
EWDEFPNGRWGDFRSPAYGEITDYYLAFKRPKVKREAIWGCPKDEADVRRVFVDFVRGKV
PQLPWCDTPLADEAGAIADNLRWMNSHGFLTINSQPRVNGAPSTDPKVGWGGDDGVVFQK
AYIEFFVSPEQWEHLRKAMPAFPSLTYHAMNLAGEEHINTDRTRATAVTWGVFPGREILQ
PTVVDPVSFRVWKDEAFELWRSQWASAYPGDDEASVRAREVIERIRSTWLLVNVVDNDYA
EPESDIFSVFKHAATKAMSTDQLRAAVLAAEAENRALRERAEALQSHVARQSKDLEFQAE
RAARAEGEVAALRRRVRELEMRTVLAGSVASSLQPAGLAAPRYLAATAAPGAASAASAAA
SGAAVATVKA
>A0A7Y7E8R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces morookaense|TrEMBL
MALGTASTRTDHARTVRELLASGERSYSFEFAAPKSEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSVAELRNVIGQYADVGIRNMLALR
GDPPGDPMGEWVHHPDGIRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDVRYFVD
KCRAGADFAITQMFFYPEDYLRLRDRVVAAGCDTPIIPEIMPVTNVRQIERFAQLSNAAF
PPALAERILAVQDDPAAVRSIGIEYATELCARLMAEEIPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A2E0QJA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MTIRYEINPPKISNSSIEQIQKLEHRIEKISHFCDGIHVTDSVLGIERXSPLIIGAEIKQ
KFPXLDVTISLRVIDKXIAQILXFTDAAVHANLDGILVLMGDPSPENDYKSGVIPSAAVN
VLVQNGFNKKINLYLSLPSKPNFEKISKKVNSNPKGFVTQVIHDVXQVKRLVDYLKPKNF
XLIPCILFPSSKNSXSAEFLNLDWSNYENDFSSFVREIESVTGDVLVTSPNDFKGAXDFL
TRLQN
>A0A829W2I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster clostridioformis|TrEMBL
MKMKIREILAEGKPTLSFEVFPPKTEDAYDSVEKAAAKIAKLKPSFMSVTYGAGGGTSDY
TVGIASAIKEEYAVTPLAHLTCVSSTREKVHHVLGELKERGIENVLALRGDIPQDGSTPK
EYHYASELIREIKKAGDFCIGAACYPEGHVESANKSVDMDYLKQKVEAGCDFVTTQMFFD
NSILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTCLPSRFMSIVDRFGDNPA
AMKQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A7Z7YTZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus capitis|TrEMBL
MSQFLNQLQNNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGANVIQT
NTYGANFEKLKTFGLEHRVKEIHKAAVQIAKRAAHHDTFILGTVGGFRGVRQDDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELKSIVVATRRKYEIPIIAQLTASNTNYLVDG
TEINDALKQLVACGANVVGLNCHHGPHHMQRSFSHIELPDNAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIRYIKTAVQGLTPIKDKKVVPITKKS
NHKPTKVVKQNLTSKVKNGPTVIVELDTPKHLDTDTFFENVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQQYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A832G813|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacterium album|TrEMBL
MKVIEHLAKAKNPLISFEIIPPKRGGDISSILSLLDDLVKYNPPFIDITSHAAEVYYEET
PQGIKKIIKRKRPGTLGICALIQNKYNIDAVPHVLTKGFTREETEDFLIELNYLGIQNVL
AIRGDDSGYNKPIPQGRSVNPYAVDLVKQIMDMNKGKYLEDSLLDAKPTNFCVGVSGYPE
KHFEAPNLKTDIKFMKEKIDAGAEYVVTQMFYDNSHYFNFVKLAKEMGVSVPIIPGLKIL
TSKIQLNTVPKNFYINIPEALSDEVLAAKPEHVIDIGVEWAAKQVEELLNNNVPAVHFYI
MQNSKPIIKLMERLKL
>R7HAA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:38|TrEMBL
MKLTEIYQNKKTVLSFEIFPPKKEEELKNIDRTLEALCEVQPDFISVTFGAGGSANKNKT
IELAKKIKEDYHIEPVVHLTCLCYDRQEIDEFARQLQAEGIENILALRGDRNPDIPEKED
FKHASDLITYMKEKGDFCVAGACYPEDHPESESHMQELKALKTKVDAGAELLLSQLFFDN
HLFYDFASDCKNNGITVPVTPGIMPVTSAAQIQRMVKMCGATLPDSLQKIVERYADNKPA
MMEAGIYYAVNQILDLLANDMHGIHLYTMNNPEVAKKICAGIQHLI
>A0A0C2Z8Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp. PC08-66|TrEMBL
MFETFLTKLQSDEKFITVEITPPHGASIGQIIDNIDKLQLAHKVDGFSLTDNPLAKLKMS
GVLSAIKVQHYFQKPVIATMSMRDTNKLSMQSTLLGANDFDLRCILALTGDPAKLSDQPE
VKGVVERDSTLLLSIIYHLNKGVDYSNQSLNPPPNPIYPFAVSNSYSKDKTRLEKRILKK
LNYGARAILTQPIYDFNNAKELLEIFESAKSKSIRQSAKEAQLIMGQFPVVRARTANFIS
DKVPGIHVPKAIVDEMNLAAMDGEAKEQEVGFALSKTIFDNIMQLHGKVHLMTHNRFDLC
SDLIG
>A0A2N1TAJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetae bacterium HGW-Spirochaetae-1|TrEMBL
MKTGSRLESLLDAGEFVVTGELGPPRGNDAAVIREKGEMLRGVVDAVNITDNQTAIVRMS
SIAAASILAGMGIEPVMQMTARDRNRIAIQSDVLGASALGIRNILCISGDHQSFGNQQCC
RNVYDVDSIQMLGMVKRMRDEGKVLGSDDELRGRPGMFIGAAANPFAEPFEMRPLRLKKK
VDAGADFIQTQCIFDMKRFRDYMKVVVDMGLHERCHILAGIMPLKSAGMARYMAEQVPGV
TVPEHLIRRMAGVTKEKAAEEGIAICCEIVDELRAIDGIKGIHLMAIEWEHRVSQILEKA
KLLKQRG
>A0A1Z8VFG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Endolissoclinum sp. TMED55|TrEMBL
MSTLSNALHSSEFVVTSELTPPKGLDLAPLLEKAGLLKPYVSAINLTESHAARMAMDPVA
VGHLMLDEGVEPIVQMTSRDKNRLAIQASILGACALGISNLVFMGGDSPKNGDHPDAKPV
FDLFASQLLEAVRALNNGADLNGNTLNQHTEIFAGAVVNPGATDPDAEIENLHRKINGGA
EFFQTQAVYDVNAFSAFLEKANSPKPILAGIIPIKSVKMAQYMNERIPGVDIPNHLIEKI
AAAGEDKDEIARISIEIAADTIRELRSVNKGIHVMAIGWEQHIPTMLEQSQS
>A0A1G1N1M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium RIFCSPHIGHO2_02_FULL_45_21|TrEMBL
MSFKEKIQAPPGGQARKFLVTSEIGPPKGIETRGLLEDAGLLRDRVDAINVTDLQSSVMR
LGSLSVSIQLKQNGFEPVYQLTCRDRNRLALQSDVLSAASFGIENILVLTGDHPKLGDHP
QAKPVFDLDSVQLIQVIRQLEQGEDMAGKKLEGRSPKFCLGAVVNPGAQPLEPQILKMEK
KIEAGAEFFQTQAVYDIRAFENFLSKTKHLKTTIMAGIVLLKSAGMAKYMNENVAGIFVP
DNLIQEIQGAKDKQAKSIEIAARLIKELKPMAQGIHLMPIGWDKLVPKVLDAAGL
>A0A3R6U722|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM34-9AC|TrEMBL
MKIRDILNKDTATLSFEVFPPKKSTDFGNVEAAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGDIQKQYNVPTVAHLTCVCADRSSIGAALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKENGDFCVGGACYPEMHPDSANKNAEIQGLKEKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIIPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNLSEILKA
>A0A081GMW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp. CACIAM 14|TrEMBL
MQLRQALAEGRFAVTAEVTPPRGADVSRTLAAAAGLRGLVHAVNVTDGSRAVMRMSSLAV
CRLLLEAGIEPVLQMTCRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAGDQPDARSVN
ELEAVRLLQLVRRLNAGEDPVRGTLPDGATELFPGAAADPQSTSWSGLRSRVRRKQEAGA
RFLQTQMVMDAGCLRRFVEEITGPLGLPALAGVFLLKSARNAEFINRVVPGACIPQCLID
RLAAAADPAAEGVAIAAEQVAAYRSIAQGVHLMAIKAEHRIPEILRLAELVGVADGEVAA
QQLGHGLLLG
>A0A837JB00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter butzleri L352|TrEMBL
MFKTLIQKLQEDKYLTLETTPQHEPSMHNIIEKIKKFNLQDKIDGFSCTDNPLAKLRYNS
LFAALKLQQEFEKPVIATMTMRDRNKIALQSDLLGANDFDVRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGHPFKIEPKQIFPFAVVNSYAKNFSSLEKKMHLKI
QNGAIGIITQPIFDIENAQKLLESFDIAKENVEGDKRKSQLIFGIFPVTKLRTALFLSAQ
VPGIHVPQFWIDALEKAHSIGEEEEYKVGMELSSNLFKELNKLHPKIHLMTANRFDVANE
IIS
>A0A3Q0NFA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes serotype 1/2a (strain EGD / Mackaness)|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNEGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDDVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A7Z9VMM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piscirickettsiaceae bacterium|TrEMBL
MNISFEFFPPRTDKGKQTLAQVREELSVINPEYFSVTFGAGGSTQDATLETVLDIQKNDG
IPAAPHLSCIGSEKSKIIELLDQYKAAGINRIVALRGDIPSGVRDIGDFHYANELVTFIK
SEYNDHFRIEVAAYPEVHPQAKNIQTDLKYFANKVNAGADAAITQYFYNADAYFRFRDEV
EKLGIDVPIIPGIMPITNYTQLVRFSNMCGAEIPKWILERMKLYEDDLESLRSFGTEVVS
NLCQTLKNQGVDNFHFYSMNRANPSLLIAQNLV
>A0A522RZW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacteraceae bacterium|TrEMBL
MTPISLEFFPPKTDEQRAQLDRALPKLKALAPEFVSVTFGAGGSTLTHTPRTVRELREGH
GFEVAPHVSCMGGSRDEIRALLDDYRKLGCQRIVALRGDLPSGMASPGDFRYASDLVDFI
RREHDGWFHIEVACYPECHPQSDHAQADLKHFKAKVEAGADGAITQYFFNADAYFRFVDD
ARTAGITIPIVPGIMPIANFAQLRRFSEMCGAEIPRWIGKRMLAFGDDAEAVREFGADVV
AAMCRRLLEGGAPGLHVYTLNRARATTAMLQRIDGIANA
>A0A1W1H1E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas indicatrix|TrEMBL
MTAISFEFYPPKTDEQRTQLDRAAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAQDALLDLKHFKAKVDAGADAAITQYFFNPDAYFHFVDE
VQRLGVQVPITPGIMPISNFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGAEVV
AKLCQRLVEGGAPGLHFYTLNLAKPTVSVLKLLQG
>A0A1V4MCI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|delta proteobacterium MLS_D|TrEMBL
MKIRDFFATDPCVLSFEVFPPVRDGTIDRLVPVIDRLAELDPHFISVTYGAGGGTRDMSV
EIASLLKEKASVEVLAHLTCVGADREQIDGILRELRDKGVQNILALRGDPPAGETSFTRP
KDGFGYACELVDFIRSYNWFCVGVAGYPEGHQEAESFEADIDHLKRKIDAGSDFVITQLF
YRNEDFYRFRDAADRAGVNVPLVPGIFPVINYRQISKIVSLCGATLPRELRERIDPVRDD
DGEVARRGIDYAVRQTEDLLQHGVPGLHFYSMNRSGPVEEILNGISLPGRNNI
>A0A0A1CTN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. PAMC 25486|TrEMBL
MSPPSLIQASAPATQTAPIALSYELFPPRSAAAEAGLWDTIRELETTNPDYVSVTYGASG
SNRDTAVELLNRLLTETSLRPLAHLTCVGNTADELAEIISELLDHGVRGILALRGDLPKD
APTESRAGSLSYAQDLIELIRRVEQRRSALLCAGKVAIGVAAYPARHPESPSIEHDVEVL
LAKQRSGADFAITQVFFHADQYRDLVTRARRAGVSIPIIPGVMPLTSLRRVQRLGDLTGV
EPCPDLLDALGRADNAAESRRVGVRATVDLARAALDAGAPGIHLYTFNEHAAALEVLDKL
ALLRPGRPAVGNRTSGPALVTA
>A0A4S1CCJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomonas terrae|TrEMBL
MKIVEKMDRLQKQFISLEFFPPKDKNEWPAFFRVADRLAQLQPLFASVTYGAGGSTKGDT
LEIVSRLRNEHGLDTMAHLTCIGAYRGDLQLFLDRLVATGVDNVLALRGDLPQDAPPEFS
ACRTLLHASDLAAFIKECHPDLGIGVAGYPEVHPDAVDAEHDLSYLKLKLDQGGDFAITQ
LFFDNDHYFDFVAKARSIGVDKPIIPGIIPVVSLKVIQRIISLCGATLPAAYLAELEEAD
RRGGAAAVQKVGVAHARKQAEELLAAGVPGVHIYTLNRDQVVLDLVDGLLP
>A0A3A9IAQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas veronii|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDACRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A1T4ZCL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktothrix sp. PCC 11201|TrEMBL
MNRFRTACQTLDEFIVTAEVAPPKGADPSHMIEMVRLLKGRVHAVNITDGSRAVLGMSSL
AASIILLHHGVEPIYQLACRDRNRIGLQADLLGAQALGIRNILALTGDPVKAGDHPDAKA
VFDLESVRLLQAIDKLNQGKDWNNKILPDGATDLFPGAAVDPQSSSWSGLKSRFERKIEA
GAQFFQSQLITDFDRLDQFMTEIADSSKKPILAGIFLLKSAKNARFINKYVPGVCIPDTI
IDRLERAKHPLEEGILIASEQVKIARELCHGVHIMAVKREDLIPKILDLAGIKPLF
>B7VLL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio atlanticus (strain LGP32)|TrEMBL
MDLLTLNRIQFILETYRRLNVARDLRLFSGCFCHRESKMGYTHASHIDALNQNIAELSDN
INVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTYGANSGERDRTHSIIKEIKNQTG
LVAAPHLTCIDASREELIQIADDYWANGIESIVALRGDIPAGGGAPDMYASDLVELLKSR
HDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRAITQFFFDVESYLRFRDRCVAAG
VDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFEGLDDDPTTRQLVGASQAIDMVR
TLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A3S0WMD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas populi|TrEMBL
MSSQEHPLGISFEFFPPNTDAGRDKLMLVRDELAARNPRFFSVTYGAGGSTQARTRDTVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGIKSLVALRGDMPSGMASIGELRYANE
LVEFIRTETGDHFDIAVAAYPEAHPQAANLDKDIENFARKMKAGANMAITQYFFTADAYF
NFMDKARALGVEQPVIPGIMPITNYTKLARFSDACGAEIPRWMRKQLEGYGDDNEAIAAF
GTDVVTRLCQRLLDGGAPGLHFYTLNQAAPVLKVVDNLVG
>A0A2D7WMB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MQKFTSIASSLKKEKPLFSVEFFPPKDDAGGKRMLETAKAISPYQPDFVSITYGAGGGTR
ETTMRYASALQNDYGFEVMPHLTCVGHTVDELLEILEDFAKAGFRNVMALRGDPPKGEKV
FQAVAGGLSYGSDLVALIKENFPDFVIGVGGYPEKHPEAIDASTDLINLKTKIEAGADFI
TTQLFFDNQVYFDFVKSCHDIGITTPVLPGLLPVLSLGQAQRFCSMCKATLPLLLEKELE
NADESNQSAVGSKWTAEQILGLIGEGAPGYHIYALNKPQSTLKILESLGIEKAVV
>A0A8J5NWX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. rapae|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A1Q8TDR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromohalobacter japonicus|TrEMBL
MSTREHPLGISFEFFPPNTDAGREKLKGVRDTLAERRPRFFSVTYGAGGSTQARTFETVK
SVRQCGIDTAPHLSCIGSDKGELRERLESFREAGITNLVALRGDLPSGMGGMGELRYANE
LVEFIRKETGDHFQIAVAAYPEVHPQAPSYEHDLQNFVRKMQAGADLAITQYFFSADAYF
HFLERARAQGVEAPIVPGIMPISNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIQAF
GEEVVSNLCQRLLDGGAPGLHFYTLNQATPALRVLDNLRCDSLMHGV
>A0A2S9JX64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium myrsinacearum|TrEMBL
MSFFRQSRRADLGTNIRVSFEFFPPKTEVMEERLWETVTRLAPLNPEFVSVTYGAGGSTR
ERTARTIKRILTETDVNAAAHLTCVDATKEEVDTVVREFAAMGVKRFVALRGDPAGGVGA
HYKPTPGGYENGADLVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVEKVRRAGIYIPILPGILPIHNFTQVTNFCSKAGTHIPAWLAERFE
GLENDPQTHALVSSAVAAEQVLDLVERGVQDFHFYTMNRADLAFAICHLIGIRPASAPLE
PALAGAA
>A0A3N2DYQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinobacterium caligoides|TrEMBL
MSNNSTRISIEIVARDNNSLENELDVLTSSFNKVDTINIPDLMRFELRSWDACSAAKLAI
PHCIPHLRAIDFDLINHPDNIAAAVADMDELLIVTGDKPQDLGRSIYPTTSCQLIQYIKQ
HWPEKKVFAALDPYRQSFSQELLYCQQKISSGADGFFTQPFFDIRLMSLYAEIMPKTIIY
WGVSPVLGERSKAYWQTRNNAIFPNDFEPSMQWNREFARQALAFVRSRGQNIYFMPIRAD
LKEYLQGII
>A0A494ZZ46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. B05|TrEMBL
MKIIDKLNEDRIHISFEVFPPKTDAGFEKVKDATDKIAQLNPSYISVTYGAGGGTSKNTA
KIASHIKHELGVESLAHLTCASSTKEEVRQVIENLKELEIENILALRGDIVPGMTFPSED
RFHYAYELVEEIKKHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITTAAQMKRSQELSGTVFPRRFLALLDRFGDYPD
AMKQAGIAYATDQIIDLLANGVKNIHVYSMNKPEVAAKIIENLSEVIKC
>A0A4S2FC19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium|TrEMBL
MNEVKRFLTRGPLLFDGAMTTYKENRPAKAVLGEYIEAGANAIKTDTFSISSWLGEDREA
ALDALKTSILEAKEAAGDDVFLFGEIGPGVESDDVFSLFQTQVDVFLAAGVHNFLFETMA
APDGLAAIAAYIKEKAPDSFVIVSFAISSTGESAQGYGMQALYDALVDSKADAIGFNCHS
GPRHMVEHVKTLVRTGKPLYIAPNAGYPQVLGWRVRYGGSPDYFAAAMKEIREAGVELLG
GCCGTTPAHICQTRAMLDRLPAHIPYRNEPRKERLTGTRTENWRGKVFVELDPPKNDQID
GFLHASKAFQKAGADLITIADSPIGRPRADASLLACRLHRELGIRPLPHMTCRDRNLNAI
KALLMGLSSEGVRQVLFVTGDPLPQDSKAEVKAVYNFNSRKLMRYARDMAELSQGLAIFG
ALDVNAVNFDKQLELALEKEANGAVGFLTQPVLSKRALDNLRQARKTLKGFLFAGIYPIV
SHRNAVFLHNEIHGMDMDEKIIERYEGLNRSEGEALAQRVSKQVMKACAPYCDGFYLMTP
FQRVALMEALIVEAKALCREKMEK
>A0A729QKI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Kouka|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7X0SHL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella zeiphila|TrEMBL
MLKNKIENRQAGILTYGMTPPKVNHPAEKIAEIADKQAERLRGIGLDGLILYDVQDEADR
IDADRPFPYLATLDPTLYSKRYLAGLDVPKIIYRVIGKVGREELADWLRSDPDEDRYSVF
VGASSSKQEVAMRLPEAYRLSRELNECMKFGGVVIPERHKSKGDEHLRAAAKQEGGCSFF
VSQATYDVEASKNFLSDYYYHCREHGIPTVPILFNLAPCGSQKTLEFMKWLGISIPKWLE
NELLHAHDILDQSVRLSREVFEELFEFGLEKEIPIGCSVESVSTRKVEIEASVALLREIK
TYMDRKLRKPQMPLGV
>Q82WL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)|TrEMBL
MQSQKKFTPTFSFEFFPPQTPEGMEKLRATRIQLAQFNPKFFSVTFGAGGSTRERTLETV
LEIQAEGYPVAPHLSCIGSTRDNIRSILEKYHSHGISRIVALRGDLPSGMAQAGEFRYAN
ELVAFIRKEFGDTFWIEVAAYPEYHPQARSALEDFTNFRRKVEAGSNAAITQFFYNVDAY
LHFVEMCEAADLNIPIVPGIMPISKFSQLARFSDGCGAEIPRWIRRKLESFGDDIPSIQA
FGLDVVTALCARLLEAGAPGLHFYTLNSAVLPTKIWQRLGL
>A0A558FME8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. H3(2019)|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWSNLKLPR
>A0A241TSC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium stationis|TrEMBL
MVPRISASAPLDYLELDPAGHPRVENKEQAFSRTALSFEVIPPRHDADQAKIANLLQVLG
SYNPDYIAVTSSKRSGWLEGTAKFIEQISSTTTMRPLAHLACTAGDKRELISWINVLVDA
GVRGFLALRGDLEPGQTSLPEGYLQHGDELVRLIRQLEGEQAARFAAGRLAVAVACYPNG
HAESANDDEDFDVLLSKQRSGADLAITQLFFDAEDYLKFSQRAQLAGTKMPLIPGIMPIT
SLKRAQRMGELSGLEVPPKLIDKLSRARSPDEEYAIGMAHTVELAQAVIAAGAGCLHIYT
HNNADITQELLAEIGISASIKN
>A0A1W9TU51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_187|TrEMBL
MKSGSNLEKVLEAGHFAFTGELGPPRGTGAKEVTEKAQYLKGNVDAVNITDNQTAVVRMS
SWAACLLLIQEGLEPNFQMVCRDRNRLAMQADILGGYTHGIRNMLCLSGDHCMFGDHPDA
MGVFDIDSMQLINMVKTMRDEGKFQSGADIEDPPKIFIGAAANPFAEPYEWRVHRLGKKI
NAGVDFIQTQCIYNMDRFRKWVQQANDMGLTEKVYILAGVTPMKNVGMARYMQKKVPGIE
VPEEIIDRLKGVEKKKVADEGIKIACEQIEEFKEMKGVHGVHLMAIEWEHKVPEIAELAK
VLPRPKV
>A0A4S0LFL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.180.01.1.1|TrEMBL
FDLDSMSRLETIRIMRDNGKFLSGRKLTTPPQVFLGCAVNAFAPPYDFRPVHLGKKIAAG
AQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLCGVGPLASAKTA
>A0A2I7IJQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter inhibens|TrEMBL
MALLNFKKRDAGAVQPSSPEVEAFLENYSIEVMPRTAAKVENFRDLLPAGTRVYIAHIEG
TPIEEMVETAKRINAEGFPVMPHFPARIIQDEATLADWIARYQGEADVKQALLLAGGVAK
PHGAFDSSMQLLETGLFDKAGFSNLHVAGHPEGNKDIDPDGSMKNVSDALLWKQKFSDRT
DAKMALATQFAFEAKPIIEWADSIKAAGVDLPIHIGIAGPAKLQTLIKFAIACGVGPSLK
VLQKRAMDVSKLLLPYEPTDVIAELAAHKAANPDFNITNVHFFPLGGIKTNATWAINNGG
AAAQPVNSQG
>A0A0F2NLY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium BRH_c16a|TrEMBL
MSTETNFNSGSNLEKVLKSGQFAFTGELGPPRGTDADEVREKAKFLKGNVDSVNITDNQT
AVVRMSSWAASLIAIQEGLEPNYQMVCRDRNRLAMQADILGGSALGIRNMLCLSGDHQQF
GDHPDARGVFDIDSIQLIAMVKQMRDEGKFLSGNDIHMPPKMFIGAASNPFAEPFVWRVH
RLAKKIEAGADFIQTQCIYNMPKFREFIRMANEEGLTEKVYILGGVTPMKSVGMARYMAS
KVPGMDVPEEIINRLKGVEKGKVAQEGINIACEQIEEFKEMKGVHGVHMMAIEWEHMVPQ
IAEQAKVLPRPVFD
>A0A1H5ZS02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassococcus halodurans|TrEMBL
MNRPEISLEFFPPKSLEASFRLWDTVQTLAPLGPRFVSVTYGAGGTTRELTRDAVATIHK
HSGLRTAAHLTCVDATREETLTIARDFAKAGVTDIVALRGDPPKGANGFVPTEGGFQNSC
ELIEALKDEGNFTIRVGAYPDKHPEASSATADVEYLKRKFDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGILPIENWKGARRFAEACGTKIPAWVIEAFEAAERDGRQDLLAT
TICTELCSDLLDGGVEQLHFYTLNRPELTRDVCYALSVTPQSGLENVA
>A0A7X8SH13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flammeovirga agarivorans|TrEMBL
MKVIDRLTQAAEEKKTLFSFELLPPVRGKSIQSLFDAIDPLMEFNPAFVDVTYHREEYIY
RELPNGLFEKSVQRHRPGTVAVCAAIMHKYNVDTVPHIICGGFSKEETENILIELNFLGI
ENILALRGDAAKGEAAFTPHPDGYGYASDLVEHITSMNNGEFKYGENTGFKTGFSVGVAG
YPEKHMDASNLDTDIKYLKQKVELGADYIVTQMFFDNQKYFDFVDRCRAAGITVPIIPGI
KPLTTKKQLTLLPNIFKLDFPQELIKEAEKCKDNKEIKKLGIEWGIQQSKELIEYGVPGM
HFYSMGRSTSVKDIAEAIF
>A0A6A3CGZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hibiscus syriacus|TrEMBL
MKVIEKIQSSQQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDAIGDNGVATPEAYQNDLAYL
KRKVDAGADLIVTQLFYDTEIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKT
KIPDEITAALEPIKDNDEAVKAYGIHLGTEMCRKILANGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPQGRWGDSRN
PSYGALSDHQFMRPRARDKKLQEEWATPLKSIDDIQEKFQSYCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSPGKL
DALVKKSKSFPSLTYVAVNKNGNLISNISVKDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDHSKILLDQIQNSYYLVSLVDNNYMDGNIFGVFEDL
>A0A7W6ID81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga flocculans|TrEMBL
MLKAKVDSGADRAITQFFFDNDLYFRYLDRVRARGIEIPIVPGIVPVQNFKQTANFAAKT
GASVPDWLAARFEGLDNDVETRKLVAAAVAAEQVLDLVDRGVNEFHFYTMNRADLVYAIC
HLLGLRDQQVKAAA
>A0A238F7B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbotryum intermedium|TrEMBL
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGDDPYTLGLFDTAG
QEDYDRLRPLSYPQTDVFLVCFSVTSPASFENVKEKWFPEVHHHCPGVPCLIVGTQVDLR
DDPAVLEKLGRQKQRPVAPEAGERLSRELGAVKYVECSALTQKGLKNVFDEAICAALEPP
ARKIKKKCSILPFPATSLSGVAHPPTRPALPYFTTYQPTYLPTNSTNYLPASFSFYRLNF
RSVQARSFARSRIQPVRQPFFSFPLADRTMSRRITDKISSLDPDEPFYTFEVFPPKTSPG
VSNLISRLSRMSSLNPSWIHITWGAGGSTHSTSLQLAEAIVSKTNGLGLDACLHLTCTNM
ERSVLDEALKRAKELGVVNLLALRGDPPRGEEYWVASDGDFQHATDLIAYIKKHHGNDFC
IGVAGYPEGHADSADKSADIDYLLAKQQAGAEFVVTQLFYCVETFLKWHKACRDKGITIP
ILPGIMPIQNYQSFRRMTNLCKSHIPHQIVEDLEPIQHDDQSVKDYGVRLAVSMMRELWS
AGIRGYHLCTLNLEKSVSRVLEQLDWVEHPPSSPSIKESRANGVDASKSSSLLPSQVELL
RGKGSKRGVDGQGARKDSPTSWDEFPNGRFGDARSPAYGDLDGYGVGLKLTPAEALRQWG
SPTTLADVSNIFSSYLSAKQASIPWSEEALRAETKTITQYLVRLNDERHWWTVGSQPAVD
GAPSGDPVYGFGAKGGYVYQKAFVEFFLTEAELDQLERRAEEEAKERKEKDEGEGLIKWY
AGNREGKLRSNMNKDNVNAVTWGVFNAQDIVTTTLIEEMSFKAWSEEAFAIWLEWSHLYP
ANSASRKFIRELAETRWLVSVAHHDYKQIDGLWQWLLAAPKV
>A0A1Q3RDC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium 38-18|TrEMBL
MKIDNLFTSGKPAISFEIFPPKRDGDFQTVLQTIDALALLKPDYISVTYGAAGSERNNDT
LELASRIKKEYGIEALAHLTSVGATKEDIKRILSVFEENQIENVLALRGDLPENPIVRDF
KYAGDLVHFIKQNGAFGVGAACYPESHVESRSKTTDLIHLKQKVDQGVDFLVTQMFFDNE
KFYEFKDEVRSLDINIPITVGIMPVLNKKQIERMVAISGAHLPEKFKKILNCYEDKPAAL
QDAGIMYACEQIVDLLSSGVDGIHLYVMNKPYVAKRILDNLSGILTTLR
>A0A258GR98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium 32-64-22|TrEMBL
MSYAAIHPDWEKPRANMVDGYSLEMTAKEIEGLKEAASKIRPGTQIAVTFLPGEEMSQRV
ECAKLVRDLGFEPIVHLSARRFTSEAELEQYLSDITSQAAVKRVFIIAGDPPEPEGPYSD
SLQIIETGLLEKYGIEIVGIGGHPEGHPNVSKPDLWVWMEKKIEAIRSRGMTPLVVTQFA
FDDDAIVDWVKEMRGRGIDVPVRLGIPGPAGIKRLLGFAKRCGVGASASVMKKYGVSLTN
LIGSAGPDKLVNSLDKGLTEEAGRVRLHFYPFGALTASADWINGYAAKH
>A0A522SS32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp|TrEMBL
MPAISFEFFPPKTDEQRAQLDRAAQVLKAHGPEYASVTFGAGGSTLSYTGDTVARLHTQH
GFNVAPHLSCMGGTRAEIAALLDGYRAAGYRRLVALRGDMPSGMASAGDFRYAAELVGFI
REHCGDHFHIEVAAYPETHPQADDALCDLRHFKAKIDAGANGAITQYFFNPDAYFRFIDD
VHRLGVEVPIVPGIMPIANFSQLKRFSDLCGAEIPRWIAKRMQAHGDDADSIRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRAKATQAVLQQLF
>A7S5W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nematostella vectensis|TrEMBL
MISSNDDDSNSATSELLRKIKEKIDNHERFFSVEIFPPKTFNGATSLFGIMCRLNELEDT
KPLFADITWKPSKEPMSDKCLEPTTLLIAASARQVNNFNTIIHIPYFGTTRTQVFEHLMR
AKEFGVCGIRAQRPAPGITYENPVHEDGFSSIEDLIIFIKQEFGNDFAIAVTGYPSQRCD
WYDSDLALLKREVDAGADFITTQLFFEVETFFKFERDCRNIGIDIPIIPGILPIQNLQTV
RNLRKMNFAVKVPNEILEVLKSGKEDLEAIQAFGIQHATKMCQELFASGKVQGIHLYTLN
IEKPVMSILENLKISKEPELNKLPWQLSDVRSGEDVRPIFWASRPRSYLIRTSNWEDMPN
GRWGNSSSASFGDLKDYHLFLTGTSRKDSELLSMWGRELNSEQDVFDIFVCYLTGRDNKQ
GFKVTELPWSDGELAPETIPLVEKLVHANQNGILTINSQPSLNAVPSEDPNHGWGKPGGY
VFQKAYLEFFAREEIALELYHQLKDGTRINFHLVNSSGESDFTNANMYSPNAVTWGVFPG
SEILQPTVVDPIAFHYWKDEAFGLWKQQWGRLYPEGSRSRDIIDSIYDSYYLVNLVDNDY
VGGNSLFDILDGVIKKVQS
>A0A258GTA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium 32-64-22|TrEMBL
MSYAAIHPNWENPAANMVDGYSLEMTAKEIEGLKEAAPLIRPNTQVAVTFLPGEELSQRV
EAAIQVRALGFEPIVHLSARRIESEEQLDWYLGEITQKAGVKRVFIIAGDPPEAEGPYEN
SLQIIESGLLEKHGITIVGVGGHPEGHPNNSGEELWVWMQKKIDAVRAHGMTPLVVTQFA
FDDDAIVEWLAEMRDRGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGISITN
LIGSAGPDKLVGNLEKKLTERHGRVRLHFYPFGALTASAEWINGYDAKHS
>A0A1I4EMC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas aestuarii|TrEMBL
MESQKKFTPTFSFELFPPQSEQGIENLRLTRKKLVRLNPKYFSVTFGAGGSTREHTLETV
LEMQSEGYVVAPHISCIGSTKQKIHAILEKYQEAGIQQLVALRGDMPSGMARAGEFRYAS
ELVAYIREAFGQIFHIEVAAYPEYHPQARSAQADLENFKRKIDAGADSAITQYFYNADAY
FHFIDSCESMGISVPVVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLEGFGDDSASIHA
FGLDVVTEMCERLLKEGAPGLHFYTMNRANLTSRIWSRLGI
>A0A3P1Y4N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fretibacterium sp. OH1220_COT-178|TrEMBL
MKDFFNLPTPSYTFEIFPPKGSDNLAGTYATVDALASLSPDLISVTYGAGGTSRDNTLCI
ASGIQNRYDIWGLAHLTCVGSTKENIGQILDELRDNGVRNVLALRGDLKEPSDLGEFRHA
SDLITFIKEREGFHVFAACYPEKHLEAPSPEEDLFRLKEKSDLGVDALISQLFFDNDVFC
RFRDRARAAGVTAPMIAGIMPITSATQIDKMITMCGATVPERVRRFVGAYGHNSRALKEA
GIAYATEQIIDLLARGVDGIHLYTMNQADVVRHIDENIRGILYSTRVKRN
>A7S360|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nematostella vectensis|TrEMBL
MNMKIQKEEKFFSVEFFPPRTPNGAVNLLGTFDRLASACPLFCDVTWHPAGDPSGDKDTS
SMTIASTALNYCGLETMLHMTCANQTKASVTKNLHKAKTLGIRNILALRGDPPDGEEWKA
LEDGLAYGADMVRHIRNNFDESFTICVAGYPAGHPDCASYEDDLKHLKEKVDAGADFIIT
QLFFENKTFFKFLQDCRDIGIKVPVIPGILPIQLSRLEVPKSIMDDLQTIKDNDVAIRNY
GVQKAINMCRELLDSGLVPGLHFYTLNREVATREILTALGLWCMDPAASRPLPWRASANQ
KRFTEDVRPIFWASRPKSYLYRTSDWDEFPNGRWGNSSAPAFRDFSDHHLFYLRSKAKKE
QMLKMWGQQLNDVQDVFEVFKCYISGEKNENGVKVTSLPWNDEELALETSFIKEKLIHFN
SNGILSINSQPSVNAASSTDPLLGWGGEGGYIYQKAYLEFFASPEVVYILLQELKNYPQV
NYHVVNNHDTVDITNCDSQTPVAVTWGVFPGREIVQPTVVDPISFKIWKDEAFSLWEQQW
SRLYTEDSKSRAIINKIMNTYCLVNLVDNDFIKGNNIWDVLERVLNLIKEQGASDNVAME
TAEEDDVGHNAV
>A0A2N3PKF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter winghamensis|TrEMBL
MPGFESNKIESFIDKLQKGKKCYTYEFSAPASFCLEKLFCGLKNQSFLQELDAFICTDSP
LGKLKHSPILASLKLQNTFKIPSIATISMRDKNTLALQSELIGMNSLDLRLVLALTGDPL
RLGNQPQAKGVFEGNSALLLKIIDALNLNKDINGENLQGIPKRIYPFCVLNSYAKNKESL
YKKMREKIRNGALAIFTQPIYDESIAKELLKWCDAINLEFRTNCALVFGFFPIASYKTAL
FLHYKLPGVFVSQEWLKALEIAKKNGKEAEVGLQKSKELFKALSALQQKFHFMSANKPEI
IAQILKT
>A0A522NC31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp|TrEMBL
MPAISFEFFPPKTDEQRAQLDRAAQSLKVHQPEFASVTFGAGGSTLSYTSDTVQRLHARH
GLPVAPHLSCMGGTRAEIAALLDDYRAAGYRRIVALRGDLPSGMATPGDFHYAAELVRFI
REHSGDHFHIEVAAYPETHPQADDALRDLHHFKAKIDAGANGAITQYFFNADAYFRFVDD
VRRLGVNVPIVPGIMPIANFSQLKRFSDLCGAEIPRWIVKRMQAHGDDADAVRALGTEVV
AQLCRRLLEGGAPGLHFYTLNRARATQAVLQNLS
>A0A6L6CF71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARIGDLLATGRTFSFEFSPPKSAAGSLSLGRTIAELEPLAPSFVSVTYGAGGSTREHTR
DTVLWVRKETNIPPMAHLTCVGHTRAEIADIISTYTDAGIVNVLALAGDPPKDPADARPS
DYVYATDLIEHLKEIGNLCIGVAAHPEGHPRSPDLATDRRHLADKLRAADFATTQFFFDL
DHYLSLVNDLADLGITKPVVPGIMPVTNIAQVERMAELSGAAFPAWLRERLESGTSPEDV
RRIGVEAATELSAQLLEAGAPGLHFYTMNKSTATLEIYAQLGLPVV
>A0A6L6CZS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
VFTAEFHSLDGNGLEKAKKYADRFRGWFDGVNATDNTAAHAHASNVATAIAIKQLGLEPI
LQIVCRDKNRLAQQADIMGASMFGVENFVALTGDDVTAGDEPEARRVFDTDGPQLVRLMG
TLKRGEYMSGRKIDPAPHMFIGAVENPGAPPFEYRVQRVAKKYAAGAKFLQLQICYHQDR
LEKFCAGVRDAGLAGKIAIIPTVVLVKGARPLNFMHNSVPGIDVPADQIARVEKAADPAE
EAYLQTLEFAQHALAQPGVRGLHITDFRNDETLERLMSDLGRIRQVTTSSSIPNEVKDDH
AYSA
>A0A6I2VJS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDRGARSVTSAPTRLAGLARSRNQLATLASSRNRPIVTAECPSADGGTIDDLAARLATIA
PFVDAVNVTDNPAAHAHASNVSMAIALAGLGIEPIMQIVCRDKNRLAIQADIAGAAMFGI
VNFSALTGDDVTAGDEPEARRVFDLDGPQLVSVLAGMKAGTYLSGRKFTPTGDFFIGAVE
NPGAPPLDYRADRALLKVNAGAQMLQLQISYRPDQLEAFMSACVANGVAQRAIVLPSVCL
TKGARALSFMNDKVPGISVPAETIDRVANADDQAEEAYLLVRDLTVYALQLPGVAGIH
>A0A538DAQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTAAEAAARLTDLDVAAIGANHGAGLLAALAALEQMGKDGKPLAALPNVGLASLTGGRVI
YPHATPEYFAEFAAHARDLGAKVIGGCCGTTPAEISAIRAAVEEERKPRAPLVFDAPELV
VALGEEQRETGLSRALASGEWIVSVQLDPPLGGNSAGLVEVATALKESGQVGWVDVNDNA
TARAGMSSLMVSATIERLAQIESIPHLTTRDWSVMGLESMLLGAHAEGVRNVLAITGDPP
EVGDYPGARGVYEIDAIGLTQLMTNLNRGEDFNGRPIDAPTSFFHGVAVNPTPDDMEVEL
ERFEQKLEAGARFAMTQIVFDPEYLDRFVDRLGGAWPIPVLVGVFPLTSHRLALRLHNEV
PGIVVPQTLQDALERAGSDAAEVGFAHAKELIAASRDRAAGVYLVAPFRRPLRVLELLD
>A0A7V8WKD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPSGHPPSETGSFLDRPDFSVLCEIEPPRRPTLDHVRSQIEALKPVTDAFLIPDNHLGRA
TVSSIAVAREVADSGCASVACMNARDRNLLGFRRDLLTAAAYGVDHFLFVYGDAPKEGRR
AEDLTVRGMMEEVRTFGTGSLFSGFPSFRIGTAARWDRPLNWRARADFLVTQITSDIESL
IRWRESLDFDGQVYAGVLVLASSRMAARVNATIAGITVPQTVVEKLDGNPELGLDLALSQ
VEEIRGSGAFEGVHLVPVGRYREVAERLTQPKAPPGAGEEV
>A0A6I3FFM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSVLREKLENTNDLVFTAEFPSVDGGGMASVVQHAARLAPWFDAVNATDNPAAHAHTSNT
TTAIAMKMHGLEPIMQIVCRDKNRLAIQSDMAGAALHGITNISLLTGDDVTAGDEPEARR
VFDVDSAQAINIARIMTTGKYLSGRTISPAPDFYIGAVENAAAPPFEYRIQRALKKHRAG
ASFLQLQICYHPDRLEAFCKGVAEVAPDLKLIPTLVLVKGSRGLAFMNDKVPGIDVPAST
LARVQNASDPSVEVNKLTLELAKHALSLPGVRGLHITDFRHDDSLNTFMNDLGRTPNR
>A0A504XL87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania donovani|TrEMBL
MVKISGTMKQAVGNSRPFVSFEFVASTTEDGAIKLHETAERLPALDPLFCGITWGNHLRT
AETSIEVASTFKAKGVRNLLVTRGAPTAGFTTEPRNRGTDVGSRAAAAGAHDSSREEADA
TTSTFLAFIAAAPSSSSSGSVFPHAVDLIRFVHQHFGDYFGMVVAAFPEGGLSGNESSDD
AAAWISARRDTELLFLKKKLSAGADYVVTQGIFDVRQLKLFGVHRISGAVDLRRRIESSK
TNDSEVKYVVVAFQQPLVKRLLARGCGGVYFFHREYGSPSYMMYAAHRRGTMEKRWNALL
VSPHSGTLALGEAGVYHARLLLGSRPKPCTQFPMIQGMAELQTALTELSRIFQAFLDGRG
TRPYADELPGETVYVEHLLKLPNAQGLYTINSQPPVNGVPSPDSSYVYQKSYVEFLCHLP
SAPIVFTTLDKCPELQYTAMSAQGNVARVTAITWGVFSRARGDSNPLSPPWTRFARVGVA
FAMWAAPFPPNDVPTVAHYIQTEFVLVRVVDNVLQEPLTPLEHAVVEICPEIPLLTLLDA
TQPHPKSSLTFAPDGDALMNALGQFVRAS
>A0A7K0RHS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDQLIAEGSEPQFSFEFFPPKTEQGEENLFEAIEQLAPLEPAFISVTYGAGGSTRDKT
IEIVSRIRDRHGIEAMPHFTCVGSTVDELRETLDKMAEIGVENVLALRGDPPGGESEWTK
TEGGLEYSRELVELIRAEYPFAIGAAAFPETHIHATSAEDDLDFLKQKVDAGADFLVTQL
FFDNDAYFDFVQRAREAGIDVPIIPGIMPISNVAQLERMTTLCGATIPPALHEALLARGD
DARAVEALGVSYATLQSAELLAGGAPGIHFYTLNRSPATHAILGALKLQRPWISR
>A0A7V2JS18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKSGSNLEKVLTAGKFAVTAELGPPKNADSDVIRRKAEHLRGVVDAVNLTDCQTAIVRMS
SIAAGAILLQEGLEPVIQMTCRDRNRIGIQSDLLGAAALGVKNLLCLTGDHQSFGNHPQS
KNVHDLDSIQMLKMVKDMRDEKKFQCGEEMEVEPRFFIGAAANPFADPFEFRALRLGKKA
AAGADFIQTQIVYNVEKFKRWLEMVRQLGLDKEVYILPGVTPLKSAGMAKYMKNYVPGLD
VPDALIERISKASDPKDEGINIAVEIINQLRELEGVAGIHIMAIEWEEAVPVITKRADLL
PRPIMGDG
>A0A538E5G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSSDREGEEVPATQTGNRFLERLARGPAIVADGGMGALLSAAVPRLRTPEEANLRAPEAV
VSLHVSFINAGAELIETNTFGANRRKLGHHFLEDQLEEINSAAVKLAREAREVTGRDVFI
GGSIGPIGEPLASRVRREIFAEQAAVLEGRGADLFMVETFYDLEEVVDAIEAARSASGLP
IVALLTFDEGAETIAGVTAAEAAQRLRELDVAAIGANHGAGLLAALAALERMGKDGIPLA
ALPNVGLASLAGGRVIYPHAAPEYFAEFAAHARDLGARVIGGCCGTTPAEIAAIHSAVEE
ERKPRAPLQFDERELVVSLGEEQRETGLSRALRENEWIISVQLDPPLGGSSVGLVEVARA
LQESGRVGFVDINDNATARAGMSSLMVSATIERECGIETIPHLTTRDWSVMGLESMLLGS
HAEGVRNVLAITGDPPEVGDYPGARGVYEIDAVGLTQLITNLNRGEDFNGRPIDGPTSFF
HGVAVNPNADDLDLELERFQQKLEAGARFAMTQIVFELECLDRFAERLGGSWPIPVLVGV
FPVTSYRLALRLHNEVPGIVVPDDLQNALQDAGSEAAEIGFEHARMLIAESRRFAGVYVV
APFRKPLRVLELL
>A0A7W0S5F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGLEAMLLGAHAEGVRNVLAVTGDPPDVGDYPGSSGVYEVDAIGLCELVSRLNEGENYNG
KAIDAPTSFHLGVAVNPSADDLEHEHERFQRKLEAGARFAMTQILFDLDYLHRFLERLGG
SSPIPLLVGIWPLSSLQLAQRLHNEAPGIVVPEPVQERLRAAGADAARAGLELARELLAE
TRHLAAGAYVVAPFRQPLGILDLLTE
>D2BYV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya zeae (strain Ech586)|TrEMBL
MSFFHANHQEALNQNLAELQGRINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPLGGGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPIASA
>A0A7W1D7B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MHEVAEQPGRTVLCRTWYIRRVPSADAPSGTGSFLDRTDFSVLCEIEPPRRPALDHVRNQ
IAALKPVTDAFLIPDNHLGRATVSSIAVAREVADQGCASVACVNARDRNLLGFRRDLLTA
AAYGVDHFLFVYGDAPKEGRRAEDLTVRGMMEEVRTFGTGSLFSGFPHFRIGTPVRVDRP
LTWRARADFLVTQITPEIQALVRWRESLDFDGQVYAGVLVLASSRMAAQVNATIAGITVP
QAVVEKLDGNPELGIDLALSQVEEIRDSGAFEGVHLVPVGRYREVAERLRATKPAGPDAG
I
>A0A847PJW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MKLKEKLQNRQTVFTVELDPPLNLNIEKLLENIKVYLNQTDAINITDCPLASLRMSPIAL
SHIVQEHTNLETIFHITCRDRNLLALKAELLGAYALGVHNILALTGDHPKMGDHPNASAV
FDTDSIGLIKII
>A0A7K0X9H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRSLKNQLTYSFEFFPPKDVEGEERLWAAMSQLESIAPDFISVTYGAGGSTRDRTIRITS
EITARTHIPTVAHLTCVGSTRDELIEILGKYRDAGIKSILALRGDPTGGPRAPWTPTPNG
LSHADELVTLAAEFGGFTIGVAAFPDGHPASDGDSSHDIEVLIEKERRGATFATTQFFFE
VDKWKSLVDKLEAKGSSLPIIPGILPVTNVKQLNRMAELSGTPIPASVSEAFAKVEDNPE
DVRKLGVDIATKLCQELLEAGAPGLHFYTMNTSTATREIYSQIKDLR
>A0A2M7JIZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_8_14_3_um_filter_51_11|TrEMBL
MSDYKAGSNLEKVLKAGKFAFTGECGPPQGANITKLKEKAAHLKGCVDAVNITDNQTAVV
RMSSWAASLTVLQEGVEPNFQMVCRDRNRLAAQSDVLGVYSHGIRNMLCLSGDHQKFGNH
PEAKNVFDIDSIQLINVVKTMRDEGKFMNGQEIDVPPKLFIGAASNPFAEPYEFRVFRLA
KKIAAGADFIQTQCIYNMVRFRDFMKRVVDMGLHEKCYILAGVTPMKSVGMAQYMAKQVP
GMDVPDSLIKRLKGAPKGKAAAEGIKMAVEQIQEFKEMPGVAGVHLMAIEWEHRVREIAE
LAGMLPRPVV
>A0A3N5TSD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTDRDPSSHLHRLLLAGEFVVTAEMQTSDSADPTHVTELAETLRGRVDAVNCTDNSAAHA
HIAPMAAARLLLDQGVEPLMQLVCRDRNRLALQADLLGAAALGVRNIVCMTGDDVSTGDH
PETKPIYDIDSVHLIRMARIMRDEGTYLSGRQLTHAPDYLIGAVENPFAPPLEFRPMRLG
TKIEAGAEFVQTQICFNLEKMRLFMARCGELGLLDHVWVLAGVFVPSSAAGARYLRDQVP
GVDVPDHVIERMEATPREDQKEEGIAIALEIVEAVRQVPGVSGIHLMTINHEEAIPRVVE
GAGLLPRPSVSPLGGA
>A0A538B106|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRPWAPSSSSITRGPAGYGRWSRPSRPSTRPRRSPSSETPVRRRPSPASPTEVARLLAHP
RFELVPTTTVEEQIRFLPERAVVSVTSSPRRGLEPTVLLTERLAGAGFRAVPHLSARLVE
GPGHLARIARRLGESGIEEVFVVGGDPPAPAGPFDSALSLLRALADRGHRFARIGIAGYP
ERHPLVDDEALLEALLAKQSFASYLVTQICYEPAVILGWIGRIRRSGVSLPVHIGMPGAV
SRGKLLEMSLRVGVGDSIRYLRKHGTLMARLVRRGGYRPDGFLATLSPLLEEGSTDVAGF
HINTFNQVESTERWRRDVLARYGSAELPAS
>A0A538H6R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MANRFLERLGSGPPIVADGGMGALVSSAVPRLRCPEEANLRAPDAVVSLHVGFINAGAEL
IETNTFGANRRKLAHYFLEDEFERINSTAVKLARNAREVTGREVFVAGSIGPLGDPLPSH
ERRQLFADQASVLEGRGADLFMVETFYDLDELVDAIEAVRSVSSLPVVALLTFDEGAETL
AGVTARDAAERLAGLDVAAIGANHGAGLLAALAALEQFQTDGLPLAALPNIGLASLAGGR
VIFPHATPDYFAEFAAHARDLGARVIGGCCGTTPTEIAAIRAAVDEDRTPRAALHFEERE
LVVSLGEEQGESQLEQALRAGEWVVSAQLDPPLGSNVMGLIEVARALKDSGRVGFVDLND
NAGARAGMSALIASAAIERACGIETIPHLTTRDTTVMGLESMLFGAQAEGLRNILAVTGD
PPEVGDYPGSRGIYEVDSIGLTRLMASLNRGEDVNGRPIDAPTSFYIGVAVNPSADDLDF
ELDRFRQKIEAGARFAMTQLLFDLDYLDRFLDRIGGSPPIPLLLGICPLWSYRLALRFHN
ELPGIIVPDALQDALRDAGADAADVGMAHAKRLLREARDRVAGVYLVVPYRQPLRVLELL
DA
>A0A523SA97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKVVNLYKGNKPVFSLEVFPPRNGESLEAVLNTIDSLWSFKPAFVSVTGGALGSMRGGTI
AIAAGIKRKYGVEGIPHFTCVNKSKHDIENLLMEMKFNEIENVFALRGDPPMGQKGFIPH
PEGHKYASELVEQIKLLNEGVYILSSVEKDYKVSPTNFGIAVAGYPNGHPECPDKKKDLE
HLKIKVDNGADYIVTQLFFDIDVFLEFVENAKRIGIDIPIVPGVMPMDKYGPIKFVSKQM
GIEIPEKLKDKLEAHKDDKDAIKKILEEHTLLMCKKLVEQGSPGIQFYTMDKPEGTKKVL
QELCKE
>A0A2M8VQL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. UB-Domo-W1|TrEMBL
MELSVEFFPPKTPEGESKLHLVRERLSESLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRDSVSDMLKQYQALGIKRIVALRGDLPSGMGQYGEFHHANALVEFIR
AETGDWFHIDVAAYPETHPQAKSPATDINFFVQKMKAGANSAVTQYFYNSDAYFRFVDDA
YKLGVTQPVIAGVMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDVASIRAFGEEVVT
DLCDQLLVAGAPGLHFYSLNQADAVLAISDNLSLSRLSK
>A0A538K5N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPLTALTSAEISLPGTPDALRVRERIAALADTVDVVGLTDNHAGQPRMSPLAAVALAREQ
GVETIVHVSCRDRNRLALQSQVVGAAALGSEGVLCLYGDQVEGVPHVHDLTTTSLIAEVK
RWAAPHELAIGAVVNPFAEDLNREIRLLERKCAAGAEFVQSQMIFDLETLREFLDRTKDL
LADIRFYASVALLRNQRMADRARRLPGCLLPEAIYRQISTGGGLELATELATELATISGV
DALHIYPLGAEVATREVAATFRGARGVAAHRR
>A0A3M1DYH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoflexia bacterium|TrEMBL
SNLEKLLRAGHFVVTAEIGPPQSADPEVIRRKARLLRGVVDAANITDNQTAIVRMSSIAS
AVLAMQEGVEPIIQMTSRDRNRLAMQSDLLGAHALGIRNLLCLTGDHQSFGNHPTAKNVH
DLDSIQFIRMVRDMRDEGRFQCGDEIKGVRPAFLIGAAENPFADPLDFRPYRLAKKIAAG
VDFIQTQIILDVPRFREFMKRVVDMGLHEKVYILAGIGPLKSAGAARYMRDKVPGMRVRD
EYVERMEAAVAGIPKEDKKARKEAWEREGIRIAIEQIQEIREIPGVAGVHIMAIEWEEAV
RPIVEGAGLLPRPVVE
>A0A315DLN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. 2KL-51|TrEMBL
MSGLKLPISLEFFPPKTPEGADKLRSVREQLYSLQPEFCSVTYGAGGSTQEGTFATVGAI
LSEGVAAASHFSCIGATKASVRNELATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLV
AFIRAETNDEFHIEVAAYPEIHPQAKSPEADLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGVDVPVVPGIMPITSSTQLLRFSDACGAEIPRWIRLRLQAYGDDTDSIKAFGL
DVVSDLCEQLINGGVPAIHFYTMNQSAATLAVLQRLKALAH
>A0A521XM38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MELARRITARGSELLLFAVTPPRATVTAERARQIAEATLQRLAPLSLDGLVLYDIDDEST
RNPTQRPFPFLPTIDPATFQAEYLADWDTPVVVYRAVGKYDEDQLRAWLAAQDADRVLTV
FVGASSRHTRPATSLARAQQLWAQTRPDLRLGGVAIPERHTRRGEEHRRLIAKQEAGCSF
FVTQVVYDVNAAKNLVSDYREECTARGLEPVPIVFTFSVCGSLKTLEFLGWLGVDVPRWI
ANDLRHADDTLQESYAHALSAARDLIGYCRRMAVPFGINVESVSIRRAEIEASVDLAHQL
SQELHR
>A0A0E2GCU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter nosocomialis NIPH 386|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A2S8YSL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MYb187|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQQLGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3D3Q6T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTVGLRSNSRLERLLHQGVFAVTAEVVPPRSSDPHPVTAQARALVGYADAVNVTDNPTSS
AHMSPVAGAALVAQAGLEPVVQLTCRDRNRLGLTSDLLGAWAMGARNVLCLTGDPTKGGD
HPDARPVFDLGVLDLIRLAASLRDHRTLTSGAEIADPPRYFIGVADVPLAPSYDFARLEA
KIEAGADFVQTQIVFDTEAFGAWADQARTRGILERVFILAGVAVPGGPRSARFMRDHLPG
VVVPDRVIERLDAAGPDAPAEGVRLTVEVVDGLKEVAGVAGIHVMGLGHEDPVRRVIDAA
GLLPRPAPS
>A0A538HX19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTSTPIEVIAPGRGVPRDVSLEGVTGGRPYTHPVANGFLERLRSGLPIVADGGMGALLSA
AVPRLRCPEEACLRAPEAVVSLHVGFINAGAELIQANTFGANRRKLEQHLLADETDRINS
TAVKLAREAREITGRDVLIAGSIGPVGDAVPPSERHELFAEQAAILEGRGADLLALETFS
GLDELEDAIDATRTVSGLPIIALLSFDERAETVAGVTAAEAASRLAELDVAAIGANHGSG
LLAALAALAEMQNCGLPLAALPNLSLARLAGDRIVFPSAQPDFFGEFAAHARDLGAMVIG
GCCGTTPTEIAAIAGALADERRPQAKLVFSERELVISLGEDQLETGLGRALRQGEWVVSI
QLDPPLGGSSHGLIEVARNLRDSGRAGLVDINDNPAARARMNGLMAAVTIEREAGIETIP
HLTPRDMTLAGLESVLLGAHAEGIRNVLAVTGDPPDQGEGPGGQGVYQVDAIGLVELIGQ
LNRGEDVNGRTIDAPTSFFPGVAVNPSADDLQLELDRFRRKLAAGARFAMTQVLFDLSYL
DRFLAEVGGRSPVPLLVGLWPLWSHQLAVRVHNHVPGIVVPDDVQQALLDAGPAAADVGM
RIAQELYVEAKEKAAGVYVVAPFKKPLAAVDVIV
>A0A537YT63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDEIISERRPTFSVEFFPPKTAEATEQLYETARELRKLDLDFVSVTYGAGGSTRDGTV
EIARALKDEIGFETMAHLSCVGETTEGLAVTLDRIEAAGIENVFALRGDPPRGQEDFVQP
EGGLGSAAELAAFISGGWDFGIGAACFPEVHPEAPDLETDLRYLKTKVDAGAGFLITQLF
FDNQVYFDFVRAARAQGIEVPIIPGVIPVATFAQTKRICDLCDATIPPALEAAFEAAGGD
PEREFELGIAYAAQQCAELLIAGAPGIQFYALNRAPATRAVLATLKASRPWERVRKRTAA
RRTDRRGRKRRQVGT
>A0A538N8Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MALGLPSVMPGGQPSISDLIGAPAPTFSFEFFPPKDAAMERQLWQAIRELEPLHPSFVSV
TYGAGGSTRDNTVAVTERIATETTLLAMAHLTAVNHSVAELRNVIGRFAAAGIRNILAIR
GDPPGDPQGEWVAHPRGVLYAEDLVRLVKEAGDFCVGVAAFPYKHPRSPDIESDTAYFVS
KCRAGADFAITQMFFDADDYLRLRDRVAATGCDTPIVPGVMPVTSMGTIGRSEQLSGAPF
PAKLAAQFERIAEDPKAVRRLGIEQCGLLCDRLLAEGIPGIHFITLNRSTATREVWQQLA
LEART
>A0A0B2XVR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MLHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMTAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGYAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
SGKEFSPEISSFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGLGRFIFKASFWENTLVAK
VLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVNQTEILKEKLIPTVSIETRGTSSWKNWYLGVEA
>A0A6C7I4I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella paratyphi A (strain AKU_12601)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7G6APU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGEHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A6M8FJV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas campi|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVNVPTAPHLSCVGDSKEELRSLLQQYQNSGIRRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKAKAGANSAITQYFFSADCYFY
FVERVRKLGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDLQSIQGFG
EQVVSEMCERLLEGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A8I1UJI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MTSPPDVTLSFEFFPPNTPAGMDKLRAVREELAAFAPAFYSVTYGAGGATREKTLATVLE
IAAERRPVAPHLSCVGATRESVRELLATYRAHGIGRIVALRGDLPSGMVDTGDFRYASDL
VAWVRAETGDWFHIEVAAYPEMHPQARSPHDDLRAFAAKMRAGASSAITQYFYNADAYLR
FRDDARRLGIDAPIVPGIMPIGNFAQLARFSDACGAEIPRWIRNRLASYGDDIESIRSFG
AEVVTDLCRRLLAEGAPGLHFYTLNQAGHSGRILEALAPARRAGAAGRR
>A0A858SBY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGK
ARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVKTGEEFTPEIARFSR
QPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAKALLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKQS
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>F7HIS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callithrix jacchus|TrEMBL
MDHRKARVLPAGHYCPSLGIRASQAGSVRFSVPPSISRNPAMVNEARGNGSLNPCLEGNA
SSGSESSKDSSRCSTPGLDPDRHERLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCHQRLEEIT
GHLHKAKQLGLKNILALRGDPTGDQWEEEEGGFNHAVDLVKHIRSEFGDYFDICVAGYPK
GHPDAESFEADVKHLKEKVSAGADFVITQLFFEADTFFHFVKACTDIGITCPILPGIFPI
QGYHSLRQLVKLSKLELPQEIKDVIEPIKDNDAAIRNYGIELAVSLCRELLASSLVPGLH
FYTLNREVATTEVLKRLGLWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKNYYLFYLKSKSPREELLKMWGEELPSEESVFEVFVHYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGVLTINSQPNINGKPSSDPIVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEGSPSRAIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDTLELLNRPTQNEREAETL
>A0A7X8XKU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MRILHRRIRPCSPPPGRLPHSGLLRRAGFPPLRRQQGSVDWQPLPRCVNLRRGPPVLPRV
GPHLPGEVAGLKRILEISELREFFGSNPPQVSFEFFPPKTAEAEARLWKTIVHLEPLAPT
FVSVTYGAGGSTRERTHGTVRRILNQTGLTPAAHLTCVGASRQEVDQVARGYWEAGVRHL
VALRGDPPAETGVYVPHPEGYAHTSDLVRGLKNLADFEISVATFPEGHPETVSIDLELEN
LKRKIDAGATRAITQYFFDTDLYFRFLDRASAAGIDIPIVPGILPVTSVANLIRFSQTCG
ATVPEWLNRLFEGLDDIPQIRNLLAMQVAASQCLLLRRAGVEHFHFFTMNRAELTWALCR
VLGLQTSPILDQALA
>A0A6P1U897|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinimarinibacterium sp. NLF-5-8|TrEMBL
MADSVTFSFELFPPRTPAGVDKLPEVIARLAHVRPSFFSVTYGAGGSEQDGTYGTVMRVA
QQTGIEAAPHLTCIGSTRTHIAELLQRYRDSGIRRIVALRGDLPATSMSSEAPGELRYAN
ELVSFIREQHGDHFALEVAAYPEVHPQALSPAADFAAFQRKVEAGASGAVTQYFYNADAY
FDFAERCARARIGIPLIAGIMPITNHAQLIRFSAACGADIPRWIRLRLEQYQDDKASLQD
FGLEVVARLCRTLLDGGAPGLHFYTLNQAEPTLRLWQHLGLPMPI
>A0A0M3C591|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. IITKGP-BTPF85|TrEMBL
MKIVDHISNAKGKTLFSFELLPPAKGQGIQSIFKTMDALMEFKPPFIDVTYHREDYMYKK
HESGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDPDFIPTEGGHAFATDLLQQVADMNQGQYLHEDIAISEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVNKCRENDIHIPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSEAVSGCKNNADVRQVGEEWLVQQCKELIDFGAPVLH
FYTMSNPGPTKSIVEKVILRLIDLSKAAITL
>A0A1Y3SB75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor sp. An82|TrEMBL
MKIIDILNQGRPTLSFEVFPPKTSDTYDSVAKATQDIAALRPDFMSVTYGAGGGTSDYTV
GIASGIQQQYGVDVLAHLTCASSTREHVAQVLEHLKEKGIQNVLALRGDIPEGGAPAHDY
QYAAQLVKDIKAHGDFCIGGACYPEGHPESPTKNADIDHLKAKVEAGCQFLTTQMFFDNN
ILYNFLYRIREKGITVPVVAGIMPVTNGKQIARICKLSGTYLPERFKAIVDRFGDNPAAM
RQAGVAYAAEQIIDLIANGVEHIHIYSMNKPEIASSIQTSLSEVLK
>A0A0X3TCH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria marisrubri|TrEMBL
MSPSGDTEVERTGYLPVPEGFVSHSRLERVLRSGRFAVTAELNPPDSADPEDVYQAAQPL
GEVADAINATDASGANCHMSSIGICALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAALG
VSNVLCLTGDGVGVGDQPGAKPVFDFDSLTLLRTIRSMRDQGQFLSGRKITRPPQLFLGA
AENPCIPPYEWRPDRLAKKAEAGAEYIQTNYIYDIPLFEKFMARVRDEGLDQRVFIIAGV
GPLASARAARWMRSNVPGIHIPDHVIDRLEKAEKPSDEGKKICIELIQQIREIAGVAGVH
VMAYRREHLVSEIILESGVLKGRSRGRRA
>A0A0Q9PEG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frateuria sp. Soil773|TrEMBL
MPAISFEFFPPKTDEQRAQLDRTAQLLKPHAPDYASVTFGAGGSTLSYTGDTVARLHQRH
GLNVAPHLSCMGGTRAEITELLDGYRAAGYRRIVALRGDMPSGMASAGDFRYAAELVRFI
REHSGSHFHVEVAAYPETHPQADDALADLRHFKAKVDAGANGAITQYFFNPDAYFRFVDD
AQRLGVDVPIVPGIMPIANYSQLKRFSDMCGAEIPRWIAKRMQAHGDDADAIRALGAEVV
AQMCRRLLQGGAPGLHFYTLNRARATQAVLEQLH
>A0A1I6RGR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zhouia amylolytica|TrEMBL
MKVTEHIERANGKTLFSFEIIPPQKGSNINELYKNIDPLMEFNPPFIDVTTSREEFVYID
KGDGLLDRKITRRRPGTLGICAAIKHKYEVDTIPHLLCGGFTKEETEYMLIDCQYLGIKN
VMALRGDAMKHQRYFEPTAGGHPYAVDLVHQIHNLRCGQYLHETLEEGDRANFCVGVAGY
PEKHLEAPSMDFDLKKLKEKVDAGADYVVTQMFFDNQKFFEFLERAKDYGINVPIIPGLK
PIAVKRHLQLLPQVFKIDLPDALIEAVDSCKSNKEVRQVGIEWAIQQSRELKEAGVPVLH
YYSMGKSDNIKAIAEAVF
>A0A3R9SJG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELL
>A0A1F0ADE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria sp. HMSC064E01|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHSIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DNDQATRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>M6ZRR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Pyrogenes str. 200701872|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDKFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A431J633|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MSTPVSFEFFPPNTPVGVEKLKTVVQELGTLSPQYFSVTYGAGGSTREKTLSAVMDIAAA
GYEAAPHLSCVGSTRDNIAEILATYRAQGIRRVVALRGDLPSGTATAGEFRYASELVRFI
RETQGPDWHIEVAAYPEVHPQQRYAAKDLAHFADKMAAGASGAITQFFFNADAYFHFVDE
ARKLGVAQPIVPGIMPFHNYARIAQFAQRDGIEIPRWVQLKMEGFMDDAASIRAFGLDVV
TRLCERLIAGGAPGLHFYTLNQAPLVLALCERLGLGLGHKA
>A0A384IY19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. AC1-42W|TrEMBL
MALGTPSTRTDRARTVREMLATGTTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQDIAAESTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGTWVEHPQGVKYAADLVRLIKEAGDFCVGVAAFPERHPRSTDWDTDTRHFVD
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCDTPIIPEVMPVTSVRQLERFPQLSNATM
PAELKERILAVKDDAAAVRSIGIDFATRFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>D9SQZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B)|TrEMBL
MNLNERLLIFDGAMGTYYASSCNNPLPKCELANIHDKKTILNIHKEYIKAGAGAIKTNTF
GANKISLECDFDVMKEAIVSGYEIAKEATEGTDVLVFADIGPIPFLEKVDLWVGYKEIID
IFLSLGASNFIFETFSSDEYLIEISEYIKEKNSKAFILTEFAVSPEGVTRLGKSGKKLLN
TMLKAKTIDACGFNCFSGPYHLLQYSKTLDIKDKTISMMPNSGYPSMINNRVFFDNTKEY
FAEQMLEIARQGVTILGGCCGTTPEYIKEMVDKLKGLEVHNILNDGRQIETTEGLKQEKL
QEKKALTEEVKDEKRVNKNPLLEKLERGEKIIAVELDPPINTEIDFFISGAKRLKGQGID
AITIADCPIARARVDSSLLACKLKRELDITAIPHMTCRDRNINATKALLLGLNVEGINNV
LVVTGDPIPSADREEIKGVFSFNSSILSSYIRELNETTFSSPFNVCGALNLNVRNFSNEL
EKAQKKIDNGITMFLTQPVLTEEAMENLKLARKKLNAKILGGIIPVVSYRNACFMNNEIS
GINVSEEIIERYKDVSKEEATRLAVEISTGIATEMSSYVDGFYIITPFKRIDIVSEIVSN
IKNNIFTYN
>A0A8B2UI58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. 9-2|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATREELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A1I7C5M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas saccharevitans|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGKFAVTSEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYATILQISCRDRNRIAIQGEILGGAAMGAC
NLLCLTGDGVQAGDHPQAKPVFDLDSMSLLEIARAMRDEQRFDSGRHIAVPPRIFLGAAE
NPFVPPLDWRPHRLAKKVAAGAQFIQTQYCFDIERLREFMLKVNDLGLLEGPDRVFILPG
IGPLASARSARWIRANVPGVHIPDAVIARLEGAENQKEEGKQLCMDLLNEIREIPGVSGA
HIMAYRQEHTVAEIIKATGVLEGRVPWYPGRDDPKELNPESSEALLS
>A0A2T6BCE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melghirimyces profundicolus|TrEMBL
MTSRPDLRRALADGLLTGDGAMSTYLYQQGIPVGVTAEELSLSRPDWIEEVHRQYLEAGA
EILETNTYGANRERLARYGLEGKVSRINRESVAIARRVAGEKAYVVGAVGSINAGRVPNW
SRAEYRDYYEEQATALLYAGVDGLILETFLDLEELTLALEAIRPLTDLPILANVAMLEVG
RTRDGHTLTEAFAHMQKHGADGAGLNCRLGPLEIQRALEKTVVPEGLILSAFPNAGRLGL
TEGEFRYKSTPEYFGDRARALREQGVRLIGGCCGTTPEHIREVARALEGLSPVPRDNPEL
PEEKEVRPRVEVRTRPTVAEKVRRETTVIVEFDSPKDLDITGYLRGAEELNRAGVDAITL
ADNSMATTRMSNMALGSIVKERTGAEPLVHITCRDRNLIGQQSHLMGLHALGIDQILVVT
GDPTRIGDLPGASSIYDVNSFDLIRMVKQLNNGISFSGKPLRQKARFTVGAAFNPNVSRI
EAAVRRLEKKVEAGADFIMTQPVYDAESMRKVHEVTRNLPIPVFIGIMPLTSHRNALFLH
NELPGVKIPDPVMKRMEGLKGPEARRAGVELAKGLLDEALRYFRGIYLITPFHYWPMTAE
LTRHIRDRQRRDQAAVMSRN
>U1I402|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallibacterium anatis 12656/12|TrEMBL
MSYAKEIDVLNRSIADLNGDINVSFEFFPPKNEKMETLLWDSIQRLKSLQPKFVSVTYGA
NSGERERTHSVVKAIKQQTGIEAAPHLTGIDASPEQLKAIAKDYWDSGIRNIVALRGDEP
PGYDKKPFYAKDLVKLLKEVADFDISVAAYPEVHPEAKSAQADLIFLKQKVEAGASRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFVQLQKMAKVTNVKIPSWMFKLYDGL
EKDQTTRNLIGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGVRPSLAA
>A0A136MSV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica bacterium OLB16|TrEMBL
MKITDRLTPGKPSFSFEFFPPKTDEGFQQLFQVLQALEPLKPTFVSVTFGAGGSTRTKTV
ELVKRIRSEIGLVAMAHLTCVGLTRDEIGQILDDLQGAGIENVLALRGDPPKGQDHFVRT
EGGFDHASELIAFIRKGWNFAIGAACYPEKHPEALSAQKDLEALKIKVDAGVDFLTTQLF
FDNQVFFRFRDQVHAAGIHVPMIAGIMPILNNKQVQRFAQMCGASIPRELAYRIEAVEDD
EEAVRHIGTFHATLQCLGLLERGVDGIHFYTLNRSTATRAIYQLLRTTPGPA
>K5XGF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC 10392)|TrEMBL
MKFSDKIARQSPFFTFEFFPPRTDQGFDNLAARISRLATLHPLGVSITWGAGGSTKERSL
ELATLTQDQCGLDTILHLTCTNAQLGSIDAILKDAKERGIQNILALRGDPPRGQEEWIPS
DPRFTHAIDLVRHIRKSYGDYFCIGVAAYPDGHPDHLIDEGRELDCLKAKVDAGADFIVT
QLFYDVEAFFLWLKKVRQKNINVPIIPGIMPIQTYASFQRLTKLTGAKVPDRIQEELNPI
SHDDRLVKDFGVNLAVDMIQRLVTGGEVSGVHFCTLNLEKSVQRILEDLQWTHAPNRSPN
RLISDAPLPPVSSSAEPDRVVTPITAARDATQTLTSMPTTNNEPGRIDFDNVATWDDFPN
GRFGDFKSPAFGANDLWGNSGSISHEMLREWRNPKTVAELTQLFLDHLDGKISTTPFSPT
PLYPESLIILPELRRLTERGWWTVGSQPAVDGVSSSDEIFGWGPKAGYVFQKGFVEFFCE
EKDVAMLEKRVQDHGNGLVHFFAGNYKGEFSTNVPEDCRNAITWGVFPGQEIIQTTIIEQ
ESFLSWKEDAYSIWSDWASCYHPESEERKLLEEVRDRRWLININHHDYRNPQALWDFIFS
DGDGLVDGPK
>A0A0H2XAW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. campestris (strain 8004)|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAAKLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAIDADSDLKYFKAKVDAGADAAITQYFYNADAYFHFRDA
AQRLGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AGLCERLIAGGVPALHFYTLNLAKPTTQVLQLLGR
>A0A2S7XR47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatium okenii|TrEMBL
MITPLYSVELFPPKTAEGMAKLKLEISQLNTLNPAYFSVTYGAGGSTREGTLDTVNWLRE
LNIDTAPHLACIGSTREQVRELLTHYQTLGIKRLVALRGDMPSGMGAGERGNFHYANELV
QFVRTEFSDAFSIEVAAYPEYHPQSSNPARDFENFKRKVDAGADGAITQYFYNADAYFAF
VTNCQRSGINIPIIPGIMPITNYTQLARFSDTCGAEIPRWIRRQLEGFGDDVESIRAFGH
EVVLNLCQQLIAGGAPGLHFYTMNQSAPIVRLWTELHLPTK
>A0A1D3DWA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces thermolilacinus SPC6|TrEMBL
MALGTPSTRTDRARTVRDLLDSGTTYSFEFWAPKTEKGERNLWTALRRVEAVAPSFVSVT
YGAGGSTREGTVKATEQIAADTTLTPVAHLTAVGHSVAELRNMVGQFADVGIRNILALRG
DPPGDPMGEWIPHPQGLHYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDTDVRHFVDK
CRAGADYAITQMFFEPESYLRLRDRVAAAGCDTPVIPEVMPVTAVRQLDRLPQLSNAHFP
PAVKERILAVKDDAAAVRSLGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQQS
>A0A0R1MCD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus oeni DSM 19972|TrEMBL
MKLTELFKTKTVFSLEVFPPKNEMSGSEIIPTLEKLRGVSPDFISVTLGAGGTEHSKGTV
EVADFIQNKLKIPAVAHVPGLYLTKKQVLNLLDQLAEVHVNNILALRGDYIADKKPAGDF
CHANELVEFIKKERPGISIAGACYPDKHREAASFVEDITCLKRKIDSGSDHLITQLFFDN
QTFYDFKEKAEIAGINVPIEAGIMPCTNKRQIERITKVSGVPIPQKYKKMLDKYQDNKEA
LKDAGIAYAVEQIVDLVSQGVDGIHLYTMNHAEVAQRIWDETKTVFKAASKSF
>A0A7X3YNS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. SB0677_bin_5|TrEMBL
MKSQVGPSAFQQALASGQPVITAEISPPRGGSVQHVLTTADRLRGRVHALNVTDGSRAVM
GMSSVAVCRLLLERNLEPVLQMGCRDRNRIALQADLLGAHALGLRNVLCLTGDPVKAGDQ
PGARPVFDYEAVRLLRDVKNLNQGLDALAQPLPDGPTALFPGCAADPQLPSWSGLKRRLQ
RKKEAGAQFIQTQMVTDLAALRRFCRELAAPLGLPVLAGVFLLKSGKNARFINRMVPGAS
IPDAAIARLDAARTPRAEGLRMAAEQVAAVLEIAQGVHLMAIKAESAIPQILDLAGFPPP
GATNGGQRGS
>A0A1N7NHJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicyclobacillus vulcanalis|TrEMBL
MTDAVWRRWDRPPRDIEGPLGACVLFDGAMSTYVHQLGVPIGTPVEQLNLTAPDLVARVH
RQYVEAGCTVVQTNTFMANRMALERHGLTVHVGDLNRRGVEIARSAARDEASVYGTMGPA
MGGYRYGALLQDEERAVLASVYREQAEALVGAGVDGLILETFPDLEEALVAIAAVRPIVG
DLPLVVNLSPEEIGVTRDGVPLQDAFRRVREAGADVVGLNCRLGPYGILRSYEQAGLEQG
GPYAAVPNAGILQRSERDEIAYTGDTQDFSRLMLRIAQMGVRWLGGCCGTTPEYIRALRE
ALLRADGGRTGVLIPAGARDSAERTRVTRSVDGAHDGPSVVDIAREKKAIVVELDPPKHL
SIARFLQGAEALAAAGADLVTMADNSLGSVRVSNMALASLLKQQQIEPLVHVTCRDRNLI
GQQSHLMGLAVLGIRNVLLVTGDPSRYGELPGATSVYDVSSMDLTKMVRRLNEGVGFSGQ
PLKHPSRFVIGTAFNPHVHNFAKAVDRLRRKVEAGADFVMTQPVFDPELMEAIADATRDL
GVPVFIGIMPLTSARNAEFLHYQVPGIRLSEEALRRMQEAAPDEALAVGEAIARELVETA
VRLFPGLYLVTPFLRFEMTVRLTQYARALEASLVGSSGASTS
>A0A7W1WDX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cylindrospermopsis raciborskii CS-506_D|TrEMBL
MQENHTTIHTSNSLTSFREAVQAGEFLITAEVAPPKGGDISHTIAMSATLKGRVHAVNIT
DGSRAVLGMSPLAVCAILCQHGIEPICQLACRDRNRIGLQADLMGAHALGIRNVLALTGD
PVKAGDHPDARAVFDLESVRLLQLITNMNQGLDFNHRTLVDGGLDLFAGAAVDPQSKSWS
GLQSRFERKVQAGAQFFQSQLITDFEKLEKFMDKIASSYNKPVLAGIFLLKSAKNAQFIN
KMVPGVNIPDHIIQRLAKAKYPLEEGMKIASEQVRMAKDLCQGVHIMAVKKEEAIAPILD
LAGVSR
>A0A0C2VSX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jeotgalibacillus campisalis|TrEMBL
MKLTDALKEKILVADGAMGTLLYSYGTDQCFEELNISQAEHIQQIHSAYIDAGADVIQTN
TYGGNYLKLERYGLEDHVKEINSAAVRNAKAAAKIDTHVLGTIGGIRSIRPQSIELDEIK
RTFREQLYCLLLEGVDGLLLETYYDLEELSTVVEIARKATDLPIIAQVSLQEVGVLQDGT
SVAAALKQLEELGADGVGMNCRQGPFHMLQSLERVPLPKHGFLSAYPNASLPSFTDGGLQ
YNNNPEYFGEMAKSFQAQGVRLLGGCCGTTPDHTRAFAKALKGAVPIIEKKISEPEPKIE
VRSKALDLPESLPSIVASRPSVVVELDPPKKLNTEAFMRGAKALTEAGADAITLADNSLA
SPRVSNESLGHLIKEKIGARPLVHITCRDRNLIGLQSHLMGLHTLGLHDLLAVTGDPTKV
GDFPGATSVYDVSSFELIEMISQLNRGVSMSGKDLGESTSFSIGAAFNPHVKSVERAVLR
MEKKIAAGADYFMSQPVFSQEKLLDVYEHTKHIEKPMYIGLMPLTSSRNAEFLHNEVPGI
KLSDEVRERMANVSSDKEQSAKEGIAITKSLIDAALELFNGIYLITPFMRYEVTAELTKY
ANKQAAKRAGGIHNVSNIIH
>A0A7Y1BG04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. WS 5011|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVKVPTAPHLSCVGDSKAELRELLNLYKSSGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADCYFY
FVDRVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTNSIQAYG
EQVITEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A848CY43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aneurinibacillus aneurinilyticus|TrEMBL
MVMPQKNLKTYLKDNLLIGDGAMATWLYRLGVPIGVCYEELNLSNPEIISTVHRSYYEAG
ARFIQTNTYGAHRDALSRHGLQTQVQQINRSAVQVARQAVGSDAYVVGGIGSINAGRVRN
TEQMATYGDQYEEQASALLLENVDAILLETFLDVDELLLALDVIRPLTDLPIIAQLATIE
VGRTRDGHTLTRAFAELVKAGADIVGLNCRMGPAEVLRSIEGAVVPGATPLSVFPNAGRL
AMSDGEYSYASVPQYFGDSALRFRAQGARLIGGCCGTTPEHIRMMAQVLAEREPLPRVNP
EVQMEEEPIPIRVVPPVRPKGIVDTVTQRHTVIVELDPPRDLDTEKFLQGTAELRNAGAD
AITLADNSLATTRMSNLALGSIMKAKLSAEPLLHIACRDRNLIGQQSHLMGLHALGINQV
LVITGDPARFGDLPGASSVFDVSSFDLIRMIKQLNEGYSFSGKPLKQRANFVVGAAFNPH
VRQFDAALRRLEKKVEAGADYIMTQPVYDREIIEQIYEGTKHLNIPIFIGIMPLTSSRNA
EFLHNEVPGIKLSDEARERMRQYEPGEEARHEGVSIARELVDMAMERFKGIYLITPFFYY
QMTAELTRYIRKQSDVKLSIQK
>A0A660YX13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium|TrEMBL
HFEAPNLKSDIKIIKSKVDAGADYVVTQMFFDNKFYFDFVDKCRAAGIDVPIIPGLKIIT
SKAQLHSVPKNFHVTIPDKLADEIDSANPEDVLNIGVEWAAK
>A0A445MR64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MKLKEALEKRRFVVTSEVQAPIDEPPEELIKRLELIRGRVDGVTVPELEVEGIVGDAIST
CELLNKNRFESIYQTTTRDKSRPQLQKDLLLAHESGVDNLLVFTEDYRITGDSLQEMMFF
HVDTGKLASVLENMKEGHTIEGRELTSRAEFVLGSGVESGWGKNVPELELKEMEEMTRIG
AGYFLTTPVFDVAHFEKFMKRVNTFGVPVIAEVMILKTAGMAQFLNRHFKSGLVPDWIIK
KLASAPDKQKASIELFAETVKGLKDLCQGIHIITIGGEEKLRLYLDSAKLR
>A0A429E7N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. WAC 06369|TrEMBL
MRSVRPERPPTVRELLATGGRSFSFEFFPPKSEKGVRTLWRTIRELEPLRPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVDHSQAELRHLIGRLAAAGVRNMLALRGDPP
GDPMGEWVKHPDGVEYAADLVRLIRATGDFSVGVAAFPYKHPRSPDIESDTRYFVEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGGDIPIIPGIMPVTRLSTIERSEQLSGAPFPPEV
KARFDAVADDPEAVRRLGIEHAAELCRELLDQDAPGIHFITFNKSTATREVYGLLEAGGY
CGAAPVASGSVPPITA
>A0A0Q5WHY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Leaf371|TrEMBL
MYTRTLYPAERGDLRLSFEYFPPKSDEMDAQLTRTAAALNAYAPEFVSVTYGAGGSTKAR
SLTTVRRLIDDCAIPNTAAHLTCVGAPRAEVDAVVDEFAAAGVRHFVALRGDPQGGIGAR
YQPFPDGYANAAALVEALARRGRFQISVSAYPEKHPESSDVDADIDMLKRKVDNGATRAL
TQFFFDNNDFERYLERVRKAGITIPVVPGILPINQFSQVSKFAGLCGARIPEALALRLAH
LDESPEERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFKRLDDIAEG
AAA
>A0A0R2JWM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructilactobacillus lindneri DSM 20690 = JCM 11027|TrEMBL
MDSQSIFQPNPVFSLEVFPPQAQLDNEGFNEKLAILKDINPDFISVTFGAGGQINNQNPL
KIADLIQQKSKITAMAHITGLYQSQPQLSKQLAQLKKHHITKILAIRGDYRNSSQPLGDF
RHADELIAFIKGHGDFEIAGACYPQNHPESKDTEKEFYYLKQKIKAGLSFLISQMVFNNE
NFYHFQNQLAAHQIQTPVEVGIMPCTSKKQLQKITHLTGHPIPAKLTTLINYYQSDSKSM
RQAGIEFAIQQIIDLSKHHVAGIHLFTMNDVEAAKSIWDATRHTFKS
>A0A445MQU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MARNFQTDLADPNLFVVTMELVPKAESIGRSIDTVLQFADDALNDGRLSAVSITDNPGGN
PSLSPDVLGKEILDRGMDVIVHFTYRDMNRAGIESRALQLRRMGMKNILALTGDYSGKGF
GGQPAPVFDLDSVSLLCFFHMMNKKAENNGISDDFFTGCAVSPFKWTEPECYLQYYKLCK
KISAGADFIITQLGYDARKFQKLIQVLKKNNIRTPALASIYLLTPRSARVMNSGKVPGAV
VSKELFKQISKEWEADKRKGYFSAVERAAKLAAVCKGLGYRGIHIGGVHRNFKTVKRIID
LLADIENDWEYFLNEFTYSQPDHFYMFTKEDDSPLSVNRLTPKKNKAYSFQKCHFKSLYH
MHQVFFDFDSPNAPLYNKICNLLDQSKIGRHSINIFEEGFKKILLNCQQCGDCCIQHLGF
LCPESQCPKHMRNGSCGGSRDGKCEVNPEKYCVWYRAYQRFALIDKTDDMAKDYVPPRMW
ELNKTSSWINFHLGINHQTKSGDAAFRYNFERSI
>Q75EA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)|TrEMBL
MRISQKLKQRAGAADEEQPKASFSFEFFVPKTLQGVQNLYDRMDRMYQTQPEFIDITWNA
GGRLSQRTSELVATSQGVLGLETCMHLTCTNMSTALVDEALERAYEAGCENILALRGDPP
LQGTWEPCAGGFRYAKDLVAHIRARYGDHFDVGVAGYPEGHEEASGAELIGYLKEKVDAG
ADFIITQMFYDADLFLKWCDAVRAAGISVPIIPGIMPITSYAALLRRAKWCQVRLPPEFL
ERLEPVKDDDQAVREIGTVLVADMCRKILASGHVTHLHLYTMNLERASLMILERLQLIDT
GGAGVRRRPSTNETLPWRKSLNPTRRKEGVRPIFWQRRPYSYVARTSQWSADEFPNGRFG
DSSSPAYGDLDLCGHTVLRQTYQRSLELWSTPRTLLDLAALVISYLKGDLKCLPWSDVPL
HQEADALLDSLIRLNEHLVLTINSQPKVNGAPSADPIVGWGPANGYVYQKQYLEFLLPKH
HLPAFHAALTADFPTLTYFAVDADDNLASNHPDDTQANAVTWGIFPGREVLQPTIVEKAS
FLAWKDEFYRILDDWRLSFDENGAADSAALLAHLTSDYALVNIVDNDFVATADNIYCLLA
RFF
>A0A009RPI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 809848|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A8G1GS05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deefgea sp. D25|TrEMBL
MLQTKIRQRQNGIVLYGITPPKANNSAEKIAEIARVQIERIAPLGVDGLVLYDIQDEAER
TDVTRPFPFMATLDPLLYSREYLADLAIPKINYRCVGKYSAEELSADLVAMDRGISVFVG
AASREQHVNLSVTQAYALRREVNPALLVGGVAIPERHLLKNDEHLRVSRKVSEGCSFFIT
QCAYNVEAAKNFLSDYYYDCQKQGLAMVPIIFTITPCGSIKTLEFMKWLGISIPKWLEND
LVHSGDILAKSLELCKGIFSEILSYAMEKGIPIGCNIESVAIRKDEIEASLQLVHDIKAM
FAVCDRAA
>A0A7Y6YPE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTTPKISFEFFPPQNLEASFRLWDTVQVLAPMGPRFVSVTYGAGGTTRTLTRDAVATLHN
SSGLNVAAHLTCVNASKAETLEIADQFAEAGVTEIVALRGDPPKGEGKFTPHPEGFANSV
ELIEGLKARGDFSIKVGAYPDRHPEAADQAADVEWLKRKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDGAKLTPGILPIENWKGARNFAKRCGTVIPGWVENAFTKALRDGREELLA
TAICTELCSDLLEGGVDKLHFYTLNRPELTRDVCFALGVTPKVSLQNVA
>A0A6N7HNL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola sp|TrEMBL
MTDTRRDARSAWAPGTDERVLVCDGAMGTMLHAAGVPLDRSLCELNLTRPSLVRDLHTAY
LAAGARLVQTNTFDANRLRLARFGLEDSVVEINIAGARLAREAATDRDPDRAGGRGGEVV
VAGSVGPAMSASLTRRTPAGERASILREQVAALSNWVDVIILETFGDTESLGQAVEVALA
ECDLPVIAQLTFGEDGRTLRGEEPAAVAAALAGLDLAALGANCTVGPAVLREVVAELARH
CALPVSVQPNAGTPRRMGRQLRYAHNIDYFAHAATRFVAGGATIVGGCCGTTPAHIRAVA
DAVADLVPAPRRRPEPRDPNRAVARTTPTGHRPHQVSWPYQDRFVVLAGMRAPHGAGLAG
FIDQAERLTAAGADLLAITDPGPPATRVSPVAAGVLLNERVHTDVVLQVETADRSLAALQ
ADLLGAHALGLHLVVCRTGTPRVAGDYPDPGSAWDVDSIRLVAALAGLNDGTDWRGVSTP
DTTRFVIGAALRTSARDRGHELDRAEQKVVAGAHFLVTDVIYDLADARHCLTELGARGVD
VPVIATLAPFEDEITILRRTQEDPEVSAPTVLPSRTGDLDHVVRTTLDTVTELRDLVAGV
LVHLPSGRDSGATLVEALRRLGSST
>A0A3B9K6K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp|TrEMBL
MNVREYMNENTLLFDGAFGTWYAIRYEGSYEACELENLAHPERVGEIHREYIKAGAKAIK
TNTFGAYPIAMGGEERQAEVIRKGFAIAGACRREAGDAGKEVFVFADLGPAPGETPEEIT
DAYLRAAEIFLEEGAENFLFETQSTDIGLREAAAFIREKKSDAVIFASFGVLPDGFSRDG
RFYRTMLEDLWNSGLFDAVGLNCVSSAGHMKQLLAGLAERGMNLTAMPNAGYPTVRGFRT
YFENSPEYFAGRVMEIADLGVGILGGCCGTTPDYIRELSAQLSRGKVRPAKFVPRTAVNV
SREEVPSPKKILINNRFAQKIAEGKCVFAVELDSPKNADATGFMDDARRLKEAGADTITI
ADCPIARARMDSSLLACKVKRELDLDVIPHMTCRDRNVNATKALLLGLYAENIRNVLIVT
GDPIPTAERDEVKSVYHFNSRKLGAFVNSLNEETFREPIQVFGALDVNAVNFPMELKRAK
EKEAAGMVGFLTQPVLSEEALENLKLARKELTGWLLGGIIPVVSHRNAVFMNNEINGITV
SQEIIDRYEGLERKEAEDLAVEISGEIAGKIRPYIDGYYLMTPMRRISLMERILQKLQQT
EK
>A0A1F2Y186|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicyclobacillus sp. RIFOXYA1_FULL_53_8|TrEMBL
MTQPEAKVERLAEQIALAGAWPARGEKPDFRTYIKHHVVIGDGAMATFLHQSGVPVRTCY
EELCLSNPQLVEDVHRAYITAGATLLQTNTFSANRAGLGRYGLENLVQELNQRAAQIALR
AAQGKAFVFGTIGSIDGLLPYRERAAVLEEMSLPEQFEEQAQALLLEPIDGLLLESFADL
EEMLVALDAVRGLTDLPIIANLSPVTVGVTRDGVAVDEAFRQMRVHGADVVGLNCRLGPS
GILRTYEAVQIRPEDGYAAVPNAGLLHIVEGDYSYTGSSDYFAEVATDLVHQGVHLIGGC
CGTTPEHVRKVALRLAEVENRDGPDGAIHQPTSAQAPATDPATRGMATPMASAAIEAETK
RPPMPPTRMTVEQAPLQPTSSLLDRVARQTTVIVELDPPRTLDVAKYLQGARALRDAGVD
FVTLADNSLGHVRVSNMALASLLKQENIEPLVHVTCRDRNLIGQQSHLMGLNVLDIHHIL
LVTGDPSKFGDLPGATSVYDTSSIELTKMVKRLNGGIAFSGQPLAQPSQFVVGTSFNPHV
LHFGKAVDRLRRKIAAGADYVMTQPMFDTNMFKEIHDATKDFGVPIFAGIMPLVSERNAQ
FLHNEVPGIQLPAAVLERMSGTSKEQGLQEGLAIAEELIDAAMQYFKGIYLITPF
>I6APP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutaceae bacterium TAV1|TrEMBL
MSSDRPISTLFPDHRPLRSLEFFPPRDDAGVESLRAAATALRKVPWDFVSVTYGAGGSTR
QRTTQVSRILKDELGFTVMPHLTCVGHSRAELDTLADRIHADGFRNIMALRGDPPKGDTT
FTPAPDGLRHASELVELLKRRHPDFCLGVAGYPEKHPEAATFEADLDALKRKVDAGAAFV
TTQLFFDNAIYARFVEKCRAHGIHVPVIPGIMPVLSIKQIQRITSLSGTRLPAALSRRLE
VAAEDPDVVEVIGIDWALDQIRGLLALGAPGYHLYILNRAKSALALAAGLAA
>A0A3S4MGW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinirhodobacter huangdaonensis|TrEMBL
MTTPTVSFEFFPPQTLDASFRLWETVQALAPLKPGFVSVTYGAGGTTRKLTHEAVATIHK
NYGLNVAAHLTCVDATKAETLEIVDAYAEAGVTEIVALRGDPPKGADRFIPHPEGFASSV
ALIEALAADGRFTIRCGAYPEPHPEATDALADVRWLKRKTEAGATSAITQFFFEADTFFR
FRDACVKEGISAKIIPGILPIQSWKGAKGFASRCGAAIPAHVAEGFEAAIAAGREREHAT
DLCIALCEALIAGGVEDLQFYTLNRPQMTLAVCAALGVTPAAAAA
>A0A2Z4MH12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus brevis|TrEMBL
MTTRKKDLRAYLKDHLLVGDGAMATQLHGLGVPVGVSFEELCLSNPRLVHEVHTSYYQAG
ARFLETNTYSANRDALSRYGLEHKVARINRLAVAIAREAAQDDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGVDGLILETFLDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYALTDAFSELKAAGADVIGLNCRLGPAELLRSFENTVIPEDALLSVFPNAGRLG
MTDGEYAFKSSPEYFGQSALRLREQGVRLIGGCCGTTPAHVKAIADALESLEPQARVNPT
IVAGDRPSISVQNTREREKPSIVERVKTATTIIVEFDPPRDLDADQFLDGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKGRHGIDPLLHIACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMDAAVARLEKKVEAGADYIMTQPVYDAESIRNVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSTEALDRMKKVQGEAARQEGIAIAKELVDTAVRYFNGIYLITPFNYYE
MAAELIQYTRQQSSLVKLAQI
>M4S7X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. MM-1|TrEMBL
MSVSIAQMEEARRALDAPLFADLAGDCQVSFEFFPPKTEKMEETLWNAIETLAPLGPRFV
SVTYGAGGSTRERTHATVARIARETAIPAAAHLTCVDASRDEILDVAREYWAAGVRHIVA
LRGDPPREGEKFQAHPDGFENAAALVAGLKSVAPFEISVAAYPECHPDSADVAADLDNLK
RKIDAGANRAISQFFFSADAFFRFRDAVEAAGIDAEIVPGILPVSNVAQTRKFAGMCGAA
IPAWMDRLFEGLDDRPAARQLVAATIAAEMCRKLYAGGVRHFHFYTLNRAELSYAICHLL
GLRPNPAAAEKAA
>A0A520P5F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MDINHKNFELSFEIFPPRNLKASFKLWRTIEVLDKLNPNFISVTYGAGGSTRDLTQSAVS
VIAKEYNIDVAGHLTCVGSSKKEVIDIALEYEKVGAKKIVALRGDLPMDHGNRINDTDSF
SSSVELIASLKKNTSFELYVAAYPNVHPNAQSEKSDLDTLKAKFDAGADSAITQFFYEKE
DFLRFRDKCNSVGIHQNIIPGILPIDNWIKTKKFANRCGIIAPQWMNKAYENYKNNEDHN
LLSQALCTEMCDELIQEGVSSLHFYTLNDPKLTQKVCEALGRKSCPTNIKKVA
>A0A2P7QG36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas deserti|TrEMBL
MSTLAPGIASWRKPLFEDVAGDIDVSFEFFPPKTEKMEQTLWESVKTLEPLAPRFVSVTY
GAGGSTRERTHNTVARIAKETTLAAAAHLTCVEASRDEIDEVARAYWEAGVRHIVALRGD
PPEAGKKFAPHPNGYAGAADLVQGLKSIAPFEISVAAYPEMHPDAVSRQSDIDNLKRKID
AGADRAITQFFFSPDCFFRFRDEAAAAGIDAEIVPGILPVSNVAQTRKFAAMCGAGIPPW
MDRLFEGLDNLPAARQLVAATVAAELCGQLYAGGVRHFHFYTLNRAELAYAISHLLGLRP
KADQQEQAA
>A0A2A4XLE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodospiraceae bacterium|TrEMBL
MLANKIKNXESGIVLYGIVPPKKGTDAEKVKEIAALQVQRLQSLKLDGLILYDIQDEKSR
TAEARPFPFLETLDSFSYSQDHLSALAIPKIIYRSVGKYSPSELSEFISNAAQKDDLTVF
VGASSKSQTVSMSVSEAYTLKKQINSDMLLGGVTIPERHQTKKDEHIRVFNKIAQGCSFF
VSQGVYDINASKNFLSDYYYYGKEHNIPLVPIIFTLTPCGSLKTLQFMKWLGISIPPWLE
NELTHSNDIIQQSVNFSAQNWQELKAFANEKNIPIGCNIESVAVRKVEVEAAIELLQRVS
TL
>A0Z6A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine gamma proteobacterium HTCC2080|TrEMBL
MNFADEPAAGENLPILPGHFSPGRFERVLRAGQFAVTAEIAPPDSADPNEVYARAEDFNG
YVDAINATDGSGANCHMSSMGICALLTRMGYSMILQMSCRDRNRISMQGDVLGAAAMGVA
NILCLSGDGVQSGDHPEAKPVFDMDSISALSMVRHMRDNSAFLSGRSLSSPPRLFMGGAS
NPFAPPLDFRPQRLAKKIAAGAQFVQTQYCFDIERLKLFMAKTRDMGLHEKVFILPGVGP
MASAKSADWIRKNVAGVHIPDSVIKRLAGAKDQKQEGVDLCIDLMQQIQEIEGVSGIHLM
AYRQEHRIGEIVTKSKVLGTRVPWSPADSNRSST
>A0A5P3A2W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MIAETDPRGRLERVLRSGRFAITAELNPPDSADPEDVYDAARPLGEIADAVNATDASGAN
CHMSSLGISALLVRAGWEPVLQISCRDRNRIAIQGDVLGASALGVHNVLCLTGDDVSAGD
QPGAKPVFDLDSVSLLRTLRTMRDDGLFLSGRRITRPPRLFLGAAENPCVDPLDWRADRM
AKKIDAGAQFIQTNLIFDMPRFERFMDRVRDLGLHRRAYILAGIGLLPSARTARWMRARV
PGIHIPDEVIARIEAADDQAEEGKRICIELIRHVRDLPGVSGVHVMAYRREHQVSEIVLR
SGILERRRIMGHQVATQKGSGGAGAAKTLE
>A0A367WSI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira profundimaris|TrEMBL
MMTVQEKQAAHNDLRVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGTTRDR
THGSVTRIQGETGIPAAAHLTCVGHTKEEIEEIARKYWDEGIRSIVALRGDLPDAGGVYT
PTPGGYPYAVDLVAGLKAIADFDISVSAYPEMHPDAPSADFEIDYLKRKIDAGANRAITQ
FFFDNETYLRFRDKCDAAGINAPIVPGILPVTNFASLLKFADMCGASVPERLHWRFDGLD
EDPETRRMVAFHEAISQVEGLMKEGVSDFHFYTLNRAELTYAICHALGIRGTDKAAA
>A0A1C3HNT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cardiobacterium hominis|TrEMBL
MTITPEDLQALIRDYSIEITPKAAQKIGDFRPWLTEGTQVYVPNLRGTKISDCIDTCELL
QNQHMCAVPHIVLRNYRSEDELRQTLDHVQALGIDRILLLAGAASQPLGPYDSVMSMLKT
GLLQHYRFAHIGFAGHPEGAADIPRADQEAAEAQKQGYALTYPGDYAFITQFCFQMPPIA
AWLEHLQARQITLPVHIGIPGVASLQSLLRHAQACGIGSSMSFLWKNARNVRKLMSLSTP
DKLLCDLAAHRRDHPDSALRQLHFYPLGGFETTINWLRAIEAGRITLTAEGFTTHE
>A0A7L9RIZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya dianthicola|TrEMBL
MSFFHANHQEALNQNLAELQGRINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPADGGKPEMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRSELSYAICHTLGVRPVTAA
>A0A840UQT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoprunum benzoelyticum|TrEMBL
MKAGSNLEKVLAAGHFAVTAECGPPRGADPEIVRKKAAYVKGNVDACNVTDNQTSVVRMS
SVAGCVLLKEMGIEPLLQMVVRDRNRIALQSDLLGASALGVRNMLCLSGDHQKFGDDPQA
KNVFDIDSMQLIHLVRTMRDEGVFPSGQKLEGAPKFFIGCAVNPFADPFEIRVPRLKMKM
MAGADFVQTQCIYNMDKFKTYLEDAKRQGLHEKVKILAGVTPLKSAGMAKFMKKMVAGMD
IPDAVIKRIADEPKEKQAAKGIEMCIEQIQELKEMEGIAGVHVMAIEWEEKLQEIIGGAG
LLPRPVVD
>Q83A63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coxiella burnetii (strain RSA 493 / Nine Mile phase I)|TrEMBL
MDASHLSLSFELFPPKTLTGFENLKSVWRTLQDKTPDYFSVTFGAGGGNQDKTMRVVRAL
RQDFIEVAPHLTCIGLSKTAIFDLLNNYRLLGIKRIVALRGDLPLEEDIAGGDFNHANEL
VAYIRKLTGDYFHIEVAAYPEFHPETRTVQEALKNFQQKIAAGANGAITQYFYNRDAYFN
FVDACRNVGIEAPIVPGIMPISDFDKLVRFSKTCATEIPRWLYKRLESYKNDKASLKAYG
VEVVTKLCEDLIAYGVPGLHFYTLNQCEPTQTIIENLQSITSFREQAVVA
>A0A560L4D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. Ace-Pa|TrEMBL
MLQQALADGRFAITAEVMPPRGGDPGRTLRVAAGLKGLVHAVNVTDGSRAVMRMSSLALC
RLLLDIGLEPVLQLSCRDRNRIALQAELLGAHALGIRNLLCLTGDPVGAGDQPGARPVNE
LEAVRLLQLVRGFNAGEDPVKGLLNDGPTSLFAGAAADPQSPSWSGLKTRVGRKKAAGAR
FLQTQMVMQPEALKRFCGEIAAPLGLPVLAGVFLLKSARNAAFVNRMVPGALIPQALIDR
LAAAEDPAAEGINIAAEQVATYQSIAQGVHLMAVKAEERIPMILAKAGVAPVEPLSLRLR
PG
>A0A4R4ZE68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella antibiotica|TrEMBL
MPGFELICEVEPPTRPDLKKVRHQIGVMSPIADAFLIPDNHIGRATVSSVAVANEVQAMG
SRGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDDPAEGARTSQLTVRTMIEQTRE
TSYPGLNPFQVGATTRLRPVPRWKAEADFLFVQISYDVDELLRWRESVDLSIPVYAGVMV
LASSAMARNLAALPQLTIPDSLIEAVDKDRDAGIDHACEQILRIRDSGAFDGVHLIPVSR
YRQVAARLERELVAPDGGGTD
>A0A3R6V3J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM08-29|TrEMBL
MIQEKEHKGVVFSCEVFPPKRDDDIYQIYKTLDEIKTLKPDFISVTYGAGGSNSKKTATI
AAYIQNICEVEALAHMTAVGMDEASLRALLFELKKKGVENILALRGDKPRTMSQEEFDRR
YFKYATDLIPEIKKNGDFFIAGACYPEVHPESKNQEEDIQHLKQKVDLGLNCLITQMFFD
NNAFYSFMDKLEKAGIDIPVHAGIMPVTAAKQLGTSVTLSGSSVPVEMSNMIAKYGENPE
DMKKAGIEYAVNQILDLKKHGVAGVHIYSMNKADVTKQIYEASF
>A0A0E1NX10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pestis bv. Antiqua (strain Antiqua)|TrEMBL
MERKLSFEMNSAKNEKEMENIFKLIEFTDTLDPIYYTVNTEIGSSVWSDTYRTVIELREK
TDVPLIPHITINNKKEREIMQIIEKYINVGICEFFVIRGDKHVYDQDNPINYGVELIELI
RRSHKHIGIKTSLYPDFHKETTEVKEEIDWNERKYQLGVNEFISQLTLNTNALDFLSHWV
DKERPFTPSIMPLGNFSFIEKFTSSNSIDYPLWIKKFANSKSNSNEDKENIGIEIIRFLC
REYLNQRERLHVFTLNKVDVMKKIFQ
>W6ZRB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bipolaris oryzae ATCC 44560|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDQALEQAQVLGIRNILALRGDAPRSEE
YRDEDTPPEQDSNKDFTWAVDLVTYIRKQYGDYFCIGVAAYPEGHSDQSHPEHQDPVADL
PYLVEKTKAGADFIMTQLFYDVEAYDKYEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHAKLPTDILARLDAVKSDDELVKQVGVQIMDEIVEHIKARPDTCRRGFHFYTLNL
EKAVSHILEDTKLIPSTLTDDDEVIVETTPAINLEPPPNGIMPHRRRSSAVNSGPRNRVI
VSHVSAARSSNPSYEATEEEAGIPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKNDISTLFRRHIEGDLEAIPWSEQGLSP
ETLTISKQLLALNAKGWWTVASQPAVNGIKSTDPVFGWGPKNGYVFQKPFVEFFIPASEF
AALQPKLDAHDQITYFAGNAAGDFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIWREWQRIYPPRSASSTLLGELRHDYWLVNVIWGDFVNGDGLWEFLLE
>A0A4U9IX22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leclercia adecarboxylata|TrEMBL
MYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRAITQFFFDVE
SYLRFRDRCVSAGIDVEIIPGSCRFRTSNRPRNLPT
>A0A2L0R245|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. PGP41|TrEMBL
MMFPIRIEIIPAEGIVEQVQALVPRTTTLSVTCLPHHGIERTMRTAVEAADLGYTVVPHL
AARSIRSRAELTEIIRGCSAAGIGEVFVIGGDRKQPAGTYDSALPVLEDIAQYTGGTMRA
GVAGYPEGHPLASPLDLLDGLLAKQHLASHVVTQMCFVAGKIHDYAALLRREGVRLPLWA
GVAGSVPRTKLVALATQIGVGSSLKFLSRKGPLARKLLSGDRYSPDSLISGLATRPGNIT
GIHLYSFNSLASAPDYGVHPAPEQASPSAALHPALIRGAAREH
>A0A4Q2J428|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacteraceae bacterium CAVE-383|TrEMBL
MRPHNFSIEFFPPKTAEGAEKLRVARAQLAQLQPKYFSVTFGAGGSTQQGTRDTVLDILR
EGHDAAPHLSCLGSSRETLRAMLADYKAQGIKRLVALRGDLPSGYGALDLASGEFRYASE
LVEFIRAETGDWFHIEVAAYPEMHPQARSPQEDLQHFAGKVLAGADGAITQYFYNADAYF
RFVEDAQKLGVMTPVVAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASFGDDGESIRAF
GLDVVTDLCERLLAGGAPGLHFYSLNQPGPTTAIWKQLVTAD
>A0A0N0I635|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. BCO2|TrEMBL
MIQSLEEVPLPKQAFLSAYPNASLPDYRDGRLVYETNAEYFEETAKAFRDQGVRLIGGCC
GTTPKHIEAMAKALADRTPVTEKTVKRRAVSVSVQAERPAPTPLPELARTRRSVIVELDP
PKQLGIDKFLAGAKALHDAGIDALTLADNSLATPRISNAAVATIIKERIGVRPLVHMTCR
DRNLIGLQSHLMGLHTLGITDVLAITGDPSKIGDFPGATSVYDLSSFDLIRLISQFNEGL
SYSGKSLGQKTNFSIGAAFNPNVRHLDKAVERMEKKIQCGAHYFLTQPVYSEEKIVQIYE
ATKHLDTPIYIGIMPLVSARNAEFLHHEVPGITLSDEIRARMAACGDDPVQAAREGIAIA
KSLIDAAFDLFNGILLDHAVFAL
>A0A8H4D4J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] haemuloni var. vulneris|TrEMBL
MKISKKLEDAHSCSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYELNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALKKAHASGCQNILALRGDPPLD
GSESTGDFKYAKDLIRYIRKNYGDHFNIGIAAYPEGHPEEEDDLKLLGYLKEKADAGADF
IITQMFYDADNFIKWCSKIRKIGVDIPIIPGIMPISTYSAFIRRAKWSEVIIPKHFLEAL
DPIKDDDYAVREKGTELVGEMCQKLIDSGYVNHLHFYTMNLERSTIMVLEHLNLIEHVKD
NAVVGDELPWRKSLHPMRSKESIRPIFWQNRKYSYISRTSGWDEFPNGRWGDSRSPAFGD
IDLSATELLRQSPKRAYELWGCPQSLEDLSNILISYLQGEIKSLPWSDGPIGDDTEVLKP
ALVEMNRKGIFTLNSQPALSAVKSNDEVFGWGPKNGFVYQKQYLEFFIHKDAVDALLHRV
EAHNAKDAHSIVTYYAVDKNGTLSTNAHDDDINAVTWGVFPGEEILQPTIVEKVSFLAWK
DEVYRLLDEWVKIFHTKAVKEVVEDEKIDSFSKLLTGFGDNFVLCNFVNNDFTSGNNIIF
DLFQDLPVTSL
>A0A800APA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacterales bacterium|TrEMBL
MFKELVEKLRKGRFISLETTPAHLPTIDPLLDKIKKYNLLEFIDGFSTTDNPLAKLKYNS
ILAAIKLQQQFKKPVIATISMRDRNKLALQSDLLGANDFDIRAILALTGDSAKISDQPNT
KGVFEADSTLLLDIIKCFNGGIDYSGKPFKIKPKKIYPFAVSSSFAKNPKTLIKKFQKKI
EHEAVGIITQPVFSIENAKMLIELFYETREKYSNEKAKTELILGFFPITKLRTAQFLHSH
VPGINVPKEWIDKLHKASKISENEEFRVGLDKSKTLFNQILNLHPKIHIMSANRFDLVKK
ILE
>A0A367YIX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida viswanathii|TrEMBL
MKISEKLDHAHRAANSPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALDKAYKSGCQNILALRGDPPLD
GSESTGDFKYAKDLIAYIHKKYGDHFNIGVAGYPEGHPEETDEVKTLEYLKEKCDAGADF
IITQMFYDVDNFISWCSKLRKIGIDLPIIPGIMPISTYSAFLRRAKWSEISIPQHFLDAL
DPIKDDDFLVREKGTELVSEMCQKLLESGYVNHLHFYTMNLEKATVMILERLNLVEAVKS
NEIVGVTELPWRKSLNPERSKESIRPIFWQNRKYSYVTRTATWDEFPNGRWGDSRSPAFG
DIDLCASELLRQSPKRAQELWGLPQSVQDITQLVINYLKGNLKSLPWFDGAIGDDTNIIL
DNLIELNENSLITLNSQPSLNSVRSSDKVFGWGPKNGYVYQKQYLEFFCHKDVVAKLLDH
IEKYNQQQGDSTSAVISYYAVNKDGNLISNCQDDDINAVTWGVFPGEEILQPTIVEKTSF
LAWKDEVYTLFSEWLKIAAMFDADKAKVQEFNKLMGQISEDFVLCNLVNNDFLQGNEVLF
DLIKQVVQT
>A0A1Y3FXN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter sp. DmW_043|TrEMBL
MSLSRLSVELIPRSPEHLLEDVAQVKALLPAADTLNIPDLRRFALRSYQATDLVRPLFAQ
AIPHIRAIDIAPDAPLPGAEQEGLSEVLIIHGDPPPDLSYRTYPNSTETIIRRYRKEAPH
LKVYAAFDPYRRAPWQELEDIARKKEAGAQGFFTQPVFDLKLFDLCQEWLEGETVFWGLS
PVIGPRSRSYWETTNHVIFPNNFIPTLEENIRFAQAVLRTLSQTEGRAYLMPLRVKLENY
LPPLLEALN
>A0A2N4SKT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. RO1|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRTVRQQLYVRKPQFCSVTYGAGGSTHQGTFGAVQEILAE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFATKMKAGADSAITQYFFSPEAYFRFVDD
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLQEGGAPAIHFYTMNQSAATLAILERLD
>A0A1M6T9H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella ruminicola|TrEMBL
MTISEKNFRKIRKIRRFFVSLQPIMSVTEFIHQDKQARRFSFEVLPPLKGTGTAKLFADI
DKLKEFDPAYINITTHHSEFVYRELENGQYERRRIRRRPGTIAIAAAIQQRYGIPVQPHV
ICSGATIEDIEYELLDLQFLGISDLLLLRGDKAKEDSRFQPTPGGHAHTTDLMEQVKRFN
EGYFADGTPIKTPGRPFDYGVACYPEKHEEAPNLEMDMQYLKQKQDLGAQYAVTQLFFDN
EKYYAFVEKARQMGITIPIIPGIKPMAKLSQLTIVPKTFHCDIPEPLAKEVVKCKTDDDA
RQLGIEWTTEQCRDLYAHGVHNIHFYTVSAVDSVAEVVKRLL
>A0A1F8ND29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_66_10|TrEMBL
MLRSGRFAVTAELNPPDSADPEAVYERALVLATVCDAINATDASGANVHMSSVGVCALLT
RAGYEPVMQVSCRDRNRIAIQGDLLGAAAMGVRNLLCLTGDGVQAGDQPEAKPVFDLDSV
TLLRTARMLRDQGQFLGGRKLEARPHFFLGAAANPFAPPYEFRAAHLAKKVEAGAEFIQT
QFCFDVPLLRGFMAQVRDLGLDERAFILIGVGPLRSARTAEWLRSRVPGVVIPDAVVTRL
RGVPADRQRDEGKRLCVEIIREVREILGVRGVHVMAYRQEELVAEIIEEAGLLPRRPGAP
AAPAENNQEATT
>A0A2A5CHH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR86 cluster bacterium|TrEMBL
MSFSDKNEEVSVSFEFFPPADLNNAGRFWDSIDDLASLNPSFISITYGAGGTTRDRSLKI
LQRILAETSLDPIAHLTCVGSSKDEADDMARQFHAAGITRLVALRGDPPGGQDDFSAHPQ
GYANATEFIQGLSKVADFDITVAAYPEKHPESPSLEHEIDVLKQKIDAGAKRCITQFFFD
TDVYLRFVDKARSSGIDIPIIPGILPILNFSRVQDLAARCGAHIPAWLIDLFEGIETSSS
TNNMLAAAVVIEQCDKLYAAGVRDFHFYTLNKSDLARAVCHSLGVRAEGEST
>A0A1V5GAD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.BinA205|TrEMBL
MKTAELFEHKTVFSLEVFPPKPDADENVIYQTLEELSDIQPDFISVTYGAGGGKNGCKTI
QIASDIQNRYGVESVAHLPCIGLTKSQAKEILDRMEENGIENILALRGDRTDGAELCGDF
RHASDLIAFIRDNYDLNILAACYPEIHPESRGAVDDLKWLKYKVECGADHLITQLFLDNS
YFYDFYEKAQIAGVDVPIEAGIMPVTNKRQIERMVKMCGVELPKKFVRVLEKYEHNEAAL
YDAGIAYAIDQITDLITEGVDGIHLYTMNNSFIAHRIYDAVQNLISVSTKV
>A0A1S1XF06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas alfalfae|TrEMBL
MISTDTPNFASTVTEAYSLEVSAKDVGALTNAAPRILPGCAMFIPYLPGQNQAVRLAAAQ
MVRSLGFEPVPHLSARRIGSLGELQACIARLVDEAGVTRCLVIAGDPSTPKGPFPDSVSL
IETGLFERSGIRTIAVAGHPEGHPILRTTEQWEVLERKCRSIQERGMAPLIVTQFGFDAD
IVVTWLEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLASRLTEAHGDVRLHLFPFGGIAQSVEWVAHYRSRASQQDRMRSVRADQA
>A0A561CJ57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax beijingensis|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPEFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
TRKLGLDLPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLQGGGAPALHFYTMNQSAATLAVLERLG
>B7WX03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas testosteroni (strain DSM 14576 / KF-1)|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPEFCSVTYGAGGSTQAGTFTMVRDIQNE
GVGAASHFSCIGATHEKVRAELNELKAMGVKRIVALRGDLPSGYGLGGEFQYASDLVAFV
RQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VRALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQTFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A5D0U1A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura syzygii|TrEMBL
MPRLRPERPPTVRELLASGGRSFSFEFFPPKTDKGARNLWRAIRELESLHPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPEGVEYAADLVRMIRSYGDFCVGVAAFPYKHPRSADIDGDTRHFVEKCRA
GADYAITQMFFRADDYFRLRDRVAAAGCDVPILPGIMPVTQLSTIERSEQLSGAPFPPEV
RARFEAVGDDPEAVRRLGIEHAAELCRELLDQDAPGIHFITFNKSTATREVYSLVDGAGY
GARGSVPPMTA
>A0A1F4BLQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_67_19|TrEMBL
MARNGRVISFEFFPPKTPEGKEKLRATWQQLARLGPRFFSVTFGAGGSTREGTLETVLEI
RAGGYEAAPHISCVASTRAEIAAQLERYRVHGIRHLVALRGDLPSGVAAAGEFRYANELV
AFIRETTGDWFRIEVACYPEFHPQTRNAPDEVRNFKRKIDAGADAAITQYFYNADAYFRF
VDDCRAAGIAVPIVPGIMPIGNFSQLARFSDACGAEIPRWMRIKLEGYRDDSASIRAFGL
EAVTALCEKLLAAGAPGLHFYTLNQAALTTAIWQRLAI
>A0A0L6TW87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacterium bakii|TrEMBL
MRITELFEKGEFVLTAEVGPPKGVEIDHLIKDAHEFLKTRVHALNVTDNQSSVMRTGSLA
TCKVLKDEGLLPIFQITCRDRNRIALQSDVLSAALLGIENLLLLTGDYTTLGDHPQAKPV
FDLDSVSLIHAVKCLENGYDIAGNAVDGTPPKFAKGAVVSPCSDSVDVQLAKMEAKVKAG
CEYFQTQGVFEPDKFMEFMEKAKQFGVPVQLGLIIPKNVGMCRYMNANVAGVHVPDDMIK
ELQADKERTKSGDVGVEICARLIKECKDYAQGVHIMSLGWENRIPEILDMAGIAPIA
>A0A091SV77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nestor notabilis|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTRDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFFMKDCQA
IGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSM
CRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRVEDVRPI
FWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEEL
TGEESVFEVFTCYITGEPNKKGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQ
PNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKG
QNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPS
RMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A5J4PB28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
GSEHTAFSFEILPPLKGTGIGKLYDTIDTLREFTPKYINITTHRSEYVYTDLRNGLYQRN
RLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLIDLQFLGITDLLVLRGDKA
KHESIFIPEENGCLHAIELQEQINNFNKGIFIDGSKAKEAIIPFSYGVACYPEKHEESPN
IDSDIYWLKKKVEAGAEYAVTQLFYDNNKYFGFVEKARQAGINIPIIP
>A0A4Y8SAZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. RIT623|TrEMBL
MYKSHILEFVPKPSAERFAILDTLMARTQLCGWPLTVAIGDRVGSALDMSPLDAFASLAK
PAPALLHFSGKDRERRDLLAQLQRMDAAGLDQLLLLSGDRLPGHVPGQRPVRYLESVAAL
QIVRQARPHWLLAAALNPFKYQEAEGGAQYSKAEKKLAAGADLFILQLGFDIDKYQEAFD
WMQRHPHPKPLMACIMALSEGRAGMLEHVAGVTVTPSMRALLAAEAAVSKAYAKERANQR
LALQVIGLKLMGYAGVHLSGIHEVAQFDALEQAIEHLQPQFSSLQDWTPAWEAAWHAPGP
TPVTFHPPGHAWRLGQRQITASNKEKVRYHLLSAMHHQLFSRTTALSKAFGWAVTRPLWA
SPTAAQWLHQLERRIKRPMVGCDTCGSCRLEDTLYICPETCPKGLANGPCGGTSLDRCEF
GDRECVHSAKYRLAVSVGRTEVLRERLIPCVQVENRQRSSWPGWFEASPSQAPSRQPDIA
PEFNE
>A0A6N4X5U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium potabilaquae|TrEMBL
MLSIFNIQFRYNMKITDHIKKANGKTLFSLEVVPPQKGIGIEDLYANIDPLMEFKPPFID
VTTSREEYVYIDKGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKDETEY
LLVDCMYLGIDNVMALRGDAMKGHQYFEPTQGGHASAMDLVHQINDLGRGKYLHNQDQIC
DEHNKFCIGVAGYPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAR
EMGITVPIIPGIKPIATKKHLKILPQVFKIDLPEELIAEVEKAKNNDIVKQIGVEWAIAQ
CRELLDFGVPVLHFYSMGKSDNIKNVARELF
>A0A6I5BA82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4941|TrEMBL
MALGTPSTWTDHAPTVRELLATGKTSYSFEFWAPKTAKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTREGTVRATQQIAADSTLTPVAHLTAVDHSVAQLRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSDDWDSDIRHFVD
KCRAGADYAITQMFFHPESYLRMRDRVVAAGCDTPVIPEVMPITSIRQLERFAQLSNASL
PSSLKERLLAAKDDPAAVRSIGIEFATEFCAELVSEGVPGLHFITLNNSTATLEIYENLG
LHRQS
>A0A151CJR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum riftiae|TrEMBL
MFETFCDFLCDKTKKFITVEVNPPHGASIDKIIEDIRKHKLHEKVNGFSCTDNPLAKLKM
SGVLSAIKLQQTFDKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKYSDQP
EVKGVLERDSTLLLSIIYHLNNGVDYSNKPLNPAPKPIYPFAVSNSYARNMKSLQKRMVK
KLDYGARAIITQPVYDLENAKELLALFEEAKEMSVRDTAKEAHLVLGQFPIVRARTANFI
DDKVPGITVPKAIIDEMNLAAMDGEEKEQEIGFALSKRIFDDIMKAHGKVHLMTHNRFDL
CSDLIG
>A0A1Y0BWQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium dioxanotrophicus|TrEMBL
MTSTDLFESAIAKARWEIVPVRDPEKAIAALPERSTVTVGCFAKTADGYLQTLSIVERLS
GADFHAVPHIPARSFDSKNHALEIAKRYVDSGVTEVFVVGGNADEPHGPFNGAIDLLRCL
ADSNVSFSSVGVAAYPEGHPSPAFDYYGGLREKSEFASYCVTQVCFDGSAIKDEARRLRE
QDIELPMHVGVPGVLAQTELLKLSRWMGIGNSMKFLLKQRKLATRLLRPTEYNPHELIED
LLPAVHEPASGIIGLHLNTFNQVARTREWVRGMLGTDEPLGAGNHGNS
>A0A5J4R350|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
MQEQINNFNKGIFIDGSKAKEAITPFSYGVACYPEKHEESPNMDNDIYWLKKKVEAGAEY
AVTQLFYDNSKYFSFVEKARKADINIPIIPGIKPFKKLSQLSMIPKTFKVDLPEDLSREI
LKCKNEDEARQVGIEWCTAQCKELIAHKVPSIHFYSIAAADSIKEVAKRIY
>A0A543PH95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus colisei|TrEMBL
MNELLAAGRPTWSFEFFPPKTPEAEPQLWTALRELERLQPSFVSVTYGAGGSTREGTVAI
TERIAAETTMTPMAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGLDPQAEWRAH
PAGLNYAAELVELIKSMGDFSVGVAAFPEQHPRSPDFETDIARFVDKCRSGADFAITQMF
FRAEDYLRLRDRVARHGCDVPIIAGVMPVTSARQISRIVQLSGQAFPADLADRFAALDGD
RPEDKAAVRAFGVEVATELCRTLLAEGVPGIHFITMNRSTATREVYENLAHLPVTS
>A0A1Q6MMQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. 36_13|TrEMBL
MKISSIVGKDKLTLSFEVFPPKTDSDFEKVKEAAFGVAAIKPAYISVTYGAGGSTSTNTL
AIAKGIQEKYGVATIAHLTCVGASKDSIIKSLSDMRDAGIENVLALRGDKPKWFDGEPFK
EYKYASELVSTIKEFGGFSVGGACYPEVHPDSANRQEDIINLKKKVDAGCEFLTTQMFFD
NSVYYDFVENVRKAGIDVPVIPGIMPITRESQIENVIKLSGCKMPQQFIKIVDRFKEDKA
SMKQAGIIYATQQILDLYANGVKNVHVYSMNDSSVAGAIYNNLSDILSM
>A0A3B9ZUJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prolixibacteraceae bacterium|TrEMBL
MKVIDIISQSNTTIFSFELLPPLKGNDSSKIYNTIETLLDFDPKYINITTHRDEMIYVEL
PDGHIEKRIVRKRPGTVAIAANIQYKYGIPVIPHILCGGFSKSETEHVLIDLNFMGIQNV
LALRGDGQKGEHVFRPEPNGHSNANQLVEQIVNLRKGKYLELDLKNTAPMDFCIGVAGYP
EKHFEAPNLEIDLMYLKQKVDAGAEYIVTQMFFDNQKYYDFVDRCRAIGIQVPIIPGIKP
INLKNQLTVLPKLFSIDIPKELATELGKCACDDDAKIVGTEWAIQQSRDLIAHKVPSLHI
YTYGVSDNTRKIVKAVF
>A0A0C3BFB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serendipita vermifera MAFF 305830|TrEMBL
MKLTDKILNRTSLTPFYTFEFFPPRTEQGFHNLVSRIERLSKLDPLGVSITWGAGGSTKD
WSLKLASICRNEHSIDTTIMHLTCTNMQVGLVDDALRAAKENGIRNILALRGDPPRGEEY
WIPTDPRFTSAADLVKYIKSTPEFGDYFCVGVAGYPDGHTESTADEDAQISHLKAKVNAG
AEFIITQLFYDADSFLRWHSKVRTAGINVPVIPGVMPIQSYASFMRLTKLCGTRVPQQLL
DQINPIRHDDQLVKDLGIRVAVDIVRKLSQNNIQGFHFCTLNLEKSVQKVLEQLRWVGVH
AEQHNMLISVSPDHPRSFPPELVITASDAAASASYSLREIHPGSGAMNSAGKGELTSAGT
WDEFPNGRFGDSKSPAFGVNDLWDSGLGVTRQQALKDWGLPTTTDDISSLFLRYLKGEAP
STPWSDEPLQSESLPITPHLVHLNSKGWWTVGSQPAVDAVSSEDETYGWGPKGGYVFQKA
FVEFFCTKADVIMLQERIQNRGQGWLTFFAANMMDDYMTNLTEEGSNAVTWGVFPGKEIS
SSTIIERDSFMAWKDEAFGYWTQWGLFHPPDSATRKLLESIRDERWLMSIAHHDYKDSNA
LWDFLRSE
>A0A435BLQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M4A.F.Ca.ET.050.02.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVVREFADMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKSAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHEAEAA
GSAAA
>A0A1B9VCB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira sp. KO164|TrEMBL
MTVKNDIAPQGTSRSDLRISFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGST
RDRTHSSVTRIQGETGIPAAAHLTCVGHTQDEIEGIARNYWDEGIRSIVALRGDLPDAGD
KYVPTPGGYPYAVDLVEGLKRIADFDISVSAYPETHPDAPSADFEIEYLKHKIDAGANRA
ITQFFFDNEVFLRFRDKCVAAGITAPIVPGILPVTNFGSLLKFADMCGASVPKRLHWRFE
DLDEDPDTRRMVAFHEAISQVEGLMAEGVTEFHFYTLNRAELTYAICHALGIRGVAQAAA
>A0A090S9T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio variabilis|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSTPTMEETLWKSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKSETGLVAAPHLTCIDASRDELIDIAEDYWANGIKNIVALRGD
IPEGGGQPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFKQASRFAAMNKVKVPGWMQKQFE
GLDDDLMTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPEA
>A0A1Q2SL89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosoglobus terrae|TrEMBL
MQSQQKSSLIFSCEFFPPKGEQGASKLRNTRRKLALISPRYYSVTFGAGGSTQDRTFETI
IDIQAEAKSSNIEAAPHLSCIGSTQGNIRDILYQYQQRGIKRLVALRGDLPSGVVDPGDF
SHANQLVEFIRTQTGNHFHIEVAAYPEVHPQAKSARADLMNFKRKVESGANSAITQYFYN
SDAYYRFVDRCRSTAIDIPIIPGIMPIHNYVQLARFSDISGAEIPRWLRKRLDEFSDDPV
AMSAFTTDVVSDLCRRLLEAEAPGLHFYTLNRASPTLAIWDNLGLEAKYSYLSTVTTR
>A0A261RU19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella genomosp. 1|TrEMBL
MTQTHTPALSLEFFPPRDIAAQERLVRAAKQLLAMQPKYVSVTFGAGGSTREGTADTVRT
LTNMGCEAAPHLSCVGASRDQLREILARYQAEGIKRVVALRGDLPSGMGGDAGELRYASD
LVRFIRDETGDWFHIEVAAYPEMHPQAVSPSVDLDHFVTKVNAGADAAITQYFFNADAYF
DFVDRARARGVTVPIVPGIMPITNYSQLSRFSEMCGAELPRWVRLRLAEFGDDKASIRAF
GTEVVTELCQTLLDNGAPGLHFYTLNQGEATLSIWKNLEL
>A0A374R304|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. TM06-3|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFNTPSVAHLTCVGRSHADIVAKIDEYRSAGVENILALRGDLPTGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A286D3V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas wuyuanensis|TrEMBL
MPAISFEFYPPKTDEQRAQLDRTAEKLKGYAPEYVSCTFGAGGSTLSYTSETVRHLNQKH
GFMAAPHLSCVGGSREEIRELLKLYRAIGCKRIVALRGDLPSGMGHPGDLRYASDLVAFI
RAEHGDSFHIEVACYPETHPQSEDALADLKHFKAKVDAGADGAITQYFYNPDAYFHFVDA
VRKLGVDVPIVPGIMPIANFTQLRRFSEACGAEIPRWIGKRMQAYGDDADSVREFGADVV
ARLCERLIAGGAPSLHFYTLNLAKPTQNVLARLGG
>R5WZS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium sp. CAG:649|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSIEKPDYISVTYGAGGNTKGRTV
EIADRIKRQNGLESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEKGD
FNYARELIEYIHKKKGDKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRHE
>A0A2H6FWL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Abin10|TrEMBL
MSFKDALNSGRFVVTAEAGPPKGTDISKIVHEVEALKGKVDAVNVTDNQSAVMRISSTSF
CKILIDMGIEPILQMTCRDRNRIGLQSDLLGASILGIRNVLCMTGDHPNAGDHKEAKPVY
DIESVQLLGVIDALNNGKDMMGNDLQGSTDYLQGAVVTPEANPLEPQLMKFKKKVNVGAK
FFQTQAVYNIDNFKSFMGHARKYPVHPVRKDAGYNGVKILAGLVLLKSAGMANFMNKFVP
GIIVPQELIDELKAAGKEKALDTGIDIMASHIKQLKAENVCDGVHIMAIGAEDKVPAIME
RAGLL
>A0A1R1GJZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL R7-0337|TrEMBL
MKPDLRSAWEKNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYINAGAVL
LESNTYSANYDKLSKFGLEAKVADINRAGVRIARRAAGENGYVVGAIGSIRAGKRANLSS
SELKKFFSQQIAALLEEAPDGIMLETFYDVEELHLALKAVRKLSSLPVICQLAVDDSART
LDGLTLPEAFHILQQDGADVIGFNCNTGPNGIKRALGTLQGKLALPVSIYPNAGVADYVD
GQYRYGASPEYFGQMAPVFADMGSRIIGGCCGTTPKHIAEISAALKGYVVEPLPEPAAFS
APERIAVQEHLADDEGQGGGEPTLVDLVKERHTVIVELDPPRDLDIAKFMKGAEALRRAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAKFVIGAAFN
PNVKHLDKAVERLEKKIVSGADYIMTQPVYDPELIVRIAKATEHLDIPIFIGIMPLASGR
NAEYLHNEVPGIQLSAEVRSRMAGLEGEAGRAEGVLIAKELLDAAIAHFNGIYLITPFMF
YDMSVQLLEYIWEKQGRKLSPLFR
>A0A7X1C589|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria seeligeri|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIIAIHKAYIGAGADIIQTN
TYGANYIKLSRYGLEDQVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDAKLPAAPL
EEIKRSFREQLYCFLLEGVDAILLETYYDLDELKTVLKIIRETTDLPVVANVSMHEPGLL
QNGQKLSDALEELIALGADVVGVNCRLGPYHMARALETVPLYDHAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQGGARIIGGCCGTTPDHIRALRKGLKSIKPVLAKEVRPIL
ELVPEEIVDEDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AIRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKANIKVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEQGRANEEGMQIARELIDSICTCFQGIYIITPFLRYDLSI
ELAKYVQSKQQVQIVSK
>A0A2R6KT62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QS_9_67_15|TrEMBL
MALDTRPSPDRQGVETLMRGARFELMPFESFEEEITHLPNGATIAITTSPQLGIEATIER
TEQAAKQGFDVVPHVAARYVSDRSQLEEIASRLTAAGVTDIFVPGGDREEPAGAFESAYE
MLVALDELPYSFEEVGITGYPEGHEFLDEETLADAMEKKEPYATYIVTQLCYDPEAVISW
IEDIRSRGVTLPVEVGIPGVMNYQRLLQISQKVGVGDSIKFLRKTTGVLGFVRQLVGSRG
TYKPDDLVDGLAPYVNDEEYGIRGIHVYTFNQTPDTESWRRGRLGE
>A0A6I3ZJP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium sp. CBMA 226|TrEMBL
MAALDGASYEILPFKGTEDAVLAHVPRNVALSVTTTEAKGLRPTVELASSLARHGYRTSP
HIAARLVRDRHHLADIVAELDDAGVRGLFVVGGDAAEPAGAFADALSLLEALEEMGHRFD
DVGIGGYPEGHGSIARSVIDTAMEQKARHATYAVTQLCFDPATTASWAHGLVARGVTLPV
RVGIPGAVSRQKLVRISAGLGLGQSARFLRKQQNLLWRFFLPGGYSPDRLVGRLAPEIGL
PGTGIAGFHVFTFNELAKTEAWRQRLLADFESARRSR
>A0A7L2G050|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nyctibius grandis|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A357Q177|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSHTRSHSFSFEFFPTKTDAGHEKLLATARCLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVSTAPHLSCVGGSKQELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKMGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMESIQT
FGAQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWDNLKLGR
>A0A8F9YL43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. DSM 110486|TrEMBL
MHLSLAVDRLVRSAHIEAIPLRGVQDELLAAPAGTTFTVTCSSKLGLERTVEFAELLAKN
DYSVIPHLAARQVTGRGELAEFLERLGNAGITDLFVVGGDAVEPAGPYSGAADLLEALPE
LDHGITSVGVGCYPEGHPQIPEEELLTDLLRKQDNADYMVSQLCFDVGVLLAWLRSARSA
GVILPLWIGLAGPVQIRKLVDVSLRIGVGSSLRYLRKQHGMIRNLVRGSAYRPEELLSAA
VDELGPDNLGIEGIHLFSFNQIESATSWQGRFAK
>A0A7Y8PHM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. Swhac1|TrEMBL
MTKQFPISFEFFPSKTDVGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLSTISDFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYASDLVR
FIREHSGDHFHIEVAAYPEMHPQADHFDQDIKNFVTKVNAGANAAITQFFFNPDAYFYFV
ERIQKQGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIIKLCERLIAGGAPSLHFYTMNNTEPTRQLVTDLGLA
>A0A7K8WFG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sclerurus mexicanus|TrEMBL
MVNETQQSCSGSSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYETDLRHLKEKVFAGADFIITQLFFRPETFLK
FIKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYRVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A1E7IVW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium C00003063|TrEMBL
MKSESNLKRVLDAGHISVTAECGPPRGADPDIVRKKAAFVAGNVDACNVTDNQTAVVRMS
SLAGCMLIKELGIDPLIQMVVRDRNRIALQSDLLGASALGVRNLLCLSGDHQKFGDDPQA
KNVFDIDSMQLIHLAKTMRDEGVFPSGDKLQGAPDFYIGCAVNPFADPYEIRVPRLKLKM
EAGADFVQTQCIYNMDKFKTYLGDAKREGLTEKIKILAGVTPLKSAGMAKFMRRMVAGMD
IPDEVVKRIADEPKEKQAAKGIEMCIEQIQELKEMEGIAGIHVMAIEWEEKLEEIIGGAG
LLPRPIIE
>A0A518KCN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrimarina mediterranea|TrEMBL
MRLPDIYAANKFALSFELFPPKTEAGVEALFGHAQTLVGFKPAYITCTYGAGGSTQDRTL
EIAARVRKEFGLPVATHLTCVGRTADQVRDYLRRALEADVTNVVALRGDPPAGEKVFTVT
EGGYRYANELVEMIHADFPSMGVAVGGYPEVHQEAPSPEADLDNLKKKIDAGAHAIITQL
FYNNEDFYRFRDKCEAAGIRVPLIPGLLPVTNVSQIKRIASLCGAKLPQEFLSQLEACGE
DATAQFEVGVEQATAQTQGLVDAGVPGIHYYVLNKSEAASRVLTNVTL
>A0A2E2G636|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. SAT82|TrEMBL
MTTALQRTIESGQQIFTAEVMPPRGGDPSNALAMGDLLKGRVHAVNVTDGSRAVMRMSSL
AVCRLLQDXGLEPVLQMACRDRNRIALQADLLGAHALGLRNLLCLTGDPVRAGDQLDARP
VNEFDSVKLLQQVGALXRGEDPRDGDLADGPTDLFAGCAADPQSRSWSGLQRRLQRKHAA
GARFVQTQMVMDAAALERFQRDLAXPMQLPVLAGVFLLKSAKNAHFIXRMVPGAXIPXXL
IERLXRAXDPAMEGIXIAAEQVXRYLGIVQGVHLMAVRAEXRIPXILDXAGISSLPE
>A0A2H5W0F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR10|TrEMBL
MALLGILRAKAEAGERTFTVEISPPINYTTMVKTSEMVHALKDFDIAGIAVTNSTGGSFR
MNPLAVVETIRAWRPETPIVIHLTARDEGSVRSVYSRADEMNRRAVSDVLVLRGDPTPHR
SREVDAFKFSTVELVRLLREYRDTQGYAIDIFVAGHPEYPSHALAKHMAYQRRKIEAGAQ
GIIANIITDPTNYARYAEAALAHGITVPILPSVIPLTSVRRCLFLHTNLHIPVPREIVER
LERARSKEEAARVGLEITIEIVERLLRDGAPGVNFNLIFPHDIASVADILRAVRGHATIW
EKYKIEDPEEIEYYNQLRGRLS
>A0A267F943|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
MPENSSSVAKMPAKEKLQQEEQERPQPPTSRQYRPLATRIRRRIEKGRRWFSCEFFPPRT
PAAAVNLVSKFDSFARGRPLFCDVTWHPAGNPAGDSPTSSTSVASAMLNYCGIDTVLHLT
CVGQTEARLVRVLDRAKSLGLKNILALRGDLPEDADGNPGGASAAAIGGPAFASDLVRLI
RRRYGSFFCIGVAGYPAGHPEAASYAEDLRRLKEKVDAGGEFIITQLFFESADFLRFVSD
CRRVGIDCPIIPGVLPVQGYQSLRHIVKLSKLTVPDSMLRVIEPIRDNDEAIRNYGIAQC
TQMCQELLQSGQVHGIHFYTLNRDAATIRILKNIGLWREDLPRPLPWQPSANYERCAEAV
RPVFWSRRPTSYVHRTRHWDDYPHGRWGSECAEIGELRDYYLFYLTVRASKQERLRMWGS
EPTSEPDIWRVFASHLSGKPVSPDGVRVTRLPWGDEEPLPSSSESSEAAKARQRLAGLSE
RGLLATNHLLRVNGASSDHPVHGWGGSGGFVYQRAYLEFFLPGCRLPALQSALSSHGGGR
VSFHIADRSGNVNLANFSEPIALTWGVFPASEVAQPTVCDGAAFLAWRDEAFALWTEEWG
RLYEEGSPSRRLIESVAETYLLVALVDNDFTEDSVLWDLTDQVARAADGSDEVELA
>A0A543B2P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stackebrandtia endophytica|TrEMBL
MPGQPAAVADLLRSGEPMFSFEFFPPKSIKAEQVLWKAIRELESLQPSFVSVTYGAGGSS
RAMTVETTDRIASETTLLPMAHCTAVNHSIAELRNLIGHFADSGVRNILAVRGDPPGDPS
AEWEAHPDGLSYAYELVELIKSSGDFCVGVAAFPEKHPRSPDWETCTAHFINKCRAGADF
AITQFFFDWQDWVRLRDATAAAGLDTPIIPGVMPVTNAKQIEKFAELSGAAFPEALATRL
RAVAEDPVAVRAIGVEVATELSEKLLAEGAPGIHFITLNRSTSTREVWQNLRSLQPTVG
>A0A0L1JEW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus nomiae NRRL 13137|TrEMBL
MFPFPLIGGPVKLRPKPFPPRWISPQSSFFNYHLPRTFDGTDSGNKMEKITDKIAALPPD
ANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGSTAQRSLELAEICQRQ
LQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYSMHGEDDSNKDFT
FAVDLVRYIRQKYGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTQAGADFIMTQ
LTYDIEAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVQIPPQILSEL
EAVKHNDDSVKRIGVDIISNLVDGMRDIPCPGIRGFHFYTLNLEKTVSFILERCDLIPPY
SEDFDAIEDGEDISAMDGARLRSLTRRRASSINSLPHNRVIVDKLHASEVSSKASISHEA
PATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLH
VPPSVAHRIWGFPVSREDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELL
QLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLL
QKHGHEKLAWFAANAKGDFESSLPAQTSDADPIEMNPNNVNSVTWGVFRGKEIVTPTIIE
EVSFRAWGDEAFGIWDEWRSIYPRNSATERFLNETKDDVWLVCVVGQDFGAGTEMGSEEE
EDEKKFMWRVLLNAK
>A0A059DB90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eucalyptus grandis|TrEMBL
MAITLALLLLAIQVGHPDVIGQDGLATLQAYQNELAYLKSKVDAGADLIITQLFYDTDIY
LKFVNDCRQVGIHCPIVPGIMPINNYKGFIRMTGFCKTKIPAEITAALEPIKDNEEAVRN
YGIHLGTEMCKKILANGIKTLHLYTLNMEKSALAILMNLGLIEESKVSRSLPWRRPTNVF
RVKEDVRPIFWANRPKSYISRTMGWDQYPRGRWGDSRSAAYGTLTDYQFMRPRARDKKLH
EEWVVPLNSIEDVHEKFKKFCLGKFRSSPWSELDGLQPETRIINEQLGKINLKGFLTINS
QPAVNGERSDSPSVGWGGPGGYVYQKAYLELFCSPEKLNILVEKCKGFPNLTYMAVNKGG
DKWISNVGDSDVNAVTWGVFPAKEIIQPTVVDPASFLVWKDEAFEIWSRGWACLYPEGDP
TQKLLQEIQSSYFLVSLVDNDYMKSDLFAVFEDI
>A0A4Q5A1U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum subsp. globosum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLTEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAF
IRERRPDMKIYGACYPEKHPQADTLDHDIDNLKRKVDAGVTHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDRWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWANVQDLFV
>A0A1Q6J0R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium 41_21_two_genomes|TrEMBL
MKISKILRDNKVTVSFEVFPPKQWDKIEHTKDIVKEMSEYAPSFMSVTYGAAGTKSGFTQ
EIATQIKNSGVTPLSHLTCITSTRDKIHTVVNDLQENGIENILALRGDIPEGFEFPDDQY
FTHAYQLVNEIKAIDPTICVGGACYPEIHPESANRVEDIEYLKQKVDCGVEFLTSQMFFD
NDKFLNFYEMCRIKGITVPIIAGIMPITNAKQIKRSIELSNSSVPKKFYKIMERFGDDER
SMKQAGIVYATEQIIDLMANGINNIHIYTMNKPEVAGAIMNGLSDIINE
>A0A354PZR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKIIDRLREDGIHISFEIFPPKTDAGYDKVIRAAEEMAGLKPEFISVTYGAGGGTSKNTA
KIASYIKHDLHVESLAHLTCASSTKDEVRSVIASLKEQGIENILALRGDISEDMVFPSED
RFHYAYQLVEEIRRHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSARQMKRSCELSGTVFPRRFQAILDRFGDSPK
AMEQAGIAYATDQIIDLLANGVKNIHIYSMNRPEVAAAIMHNISEIIQC
>A0A5N7XR61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLAAYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELLELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEVAAYPEMHPQARNFESDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLGLKR
>A0A352DNZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKIREIFDRKTVFSFEVFPPKKTSPIETIYSTLEQLRDLRPDFISVTFGAGGSGNSVYAL
DIASKLLSEGITPMLHLPCINFTKQEIADTLARAKGSGVENVLALRGDINPDIPPVKEFL
HASDLISYIKTQGDFDIAGACYPEAHPDSESLDEDVENLKLKVDAGADHLISQLFFDNAF
FYEFRDKAAQKGINVPIEAGIMPVVNKNQIERMVTTCGASLPGKFVKIMQRYEHNPEALR
DAGIAYAINQIVDLAASGVDGIHLYTMNNPYVARKICEAVTGILGV
>A0A806VKQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidipropionibacterium acidipropionici|TrEMBL
MLSTTSPAETIAELLTRAERPLTSFEFMPPRSEEDVYRLWRATDELVPLRPDFISVTYGA
NGSRRDRTLRCTQHMVASGLRTVGHLTAVSQSVAELEQTVSDYHDAGVDHILAIRGDMPG
GAAEPWVARPDGLANATELVRLVKRVNPGACVGVGAFPDCHPASGDLDLDARIVAEKAEA
GASFAITQLFFIPEHYTDLVARVRALGCGIPIIPGIMPITSFSQIRRFGELSGTDVPADL
VARLSEVAEDRAAVREIGLEAAARLSCRLLDEGAPGLHYYTLNRSRATTELHAMVRDRRP
GLWDR
>A0A8C5E166|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gouania willdenowi|TrEMBL
TFSLKKIKCSLIMGKQTPHGDGNWQSSKSDSSGASGGDSSKESSRCSTPVLDADRSDRLR
DKMRKRIESGDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKE
TSSMMIASTAVNYCGLESILHLTCCNQSKEKITAYLNKAKHLGLKNIMALRGDPVGSEWE
DEEGGFNYAIDLVKHIRSEFDDYFDICVAGYPTGHPEAETYEADILHLKEKVDAGADFVI
SQLFFRADTFLKFVNDCRAIGIKCPIVPGVFPVQGYQSLRQLAKLSKLEVPEEITRVIEP
IKDNDAAIRNFGIHQAVEMCRLLLDSGIVPGLHFYTLNREVATMEVLRQLGLWNEDPRRP
LPWAMSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLF
YLKSKSSKEALLQMWGEELMNEQSVYEIFTCYITAQSNPCGHKVLCLPWNDEPLAPETNL
LKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALL
KILKKYEPRVNYHIVNVNGRNWTNANDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDE
AFALWIEQWAKLYEDESPSRMIVKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLSEA
QELSMGTGEL
>A0A7Z0NC39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sedimenti|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTREVVR
AVSESGITTAPHLSCIGSEKAQLRDLLAQYREEGVESLVALRGDMPSGMGSIGELRYANE
LVEFIRTETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVKQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKIVDNLAG
>A0A6L3CBH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MSRLAQALSQSEFVVTSELIPPKGIDLEPLFMKADALHQVVTAFNLTESHTAKMSMDPVA
VGHLLLDRGIEPIVQMTSRDKNRIAIQASMLGAAALGISNIVIMGGDPPQNGDHPEAKGV
FDLYSSQVLDAASALNAGADYMGNLLKGKPAMNIGAVVNPGASDLGAEIENLHRKIAAGA
GFFQSQAIYDVDALATFLDRANTDAPILAGIIPIKSVRMARFMNEKVPGIDIPEHLISEI
EAAGDDSERLAETSIDIAARIVREVRSLVKGVHIMAIGWEDKIPAIVQRATN
>A0A4S5J9D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. MPMI2T|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTTPPHVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSVITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKRESLPSDALVAERLEHLREGIEENQEKMAEAAAH
HPH
>A4XIN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T 6331)|TrEMBL
MKSFREFLSQQDIVLFDGAMGTELLNRGYNKDFPLEWANISNPDLVKSIHSDYILAGSQC
IETNTFGANECRLNLYGFEGQVEKINRNAVKIAKEVAGQTAYVIGSVGPLGKPVGSGFEI
DDKRAKEVYKKQLYFLLDEGVDAILFETAASTHEVLIAIEALKELDSNFPYIVQFSFTRD
LTTIYGEDIYKVIEFLKGIDADVVGLNCGNGPHQTLEALKIFSQHLKGPFSVQPNAGYPQ
LVQGRLVYSTSANYFASFVDEYVKYGAKIIGGCCGTTPEHIKAIKERIKTISKSVEIEVI
EKKEEQKSILKDTPSELSQKLGKKFVFTVEISPPKGIELEKTKEGVKLLKEAGADTVNIA
DSPMARVRISPIALAHILKEELGVESILHFTCRDRNLISLQSELLGAAALGVKNVLALTG
DPPSIGDYPQAKPVFDVNSEGLVLILNKLNSGTDYMGNPIGKATNFTIGVALNLNADDLD
KEIERLKRKIENGAHFIETQPIYEVEALEKFFEKVDFKLPPILGGILPLRSSRHAEFLHN
EVPGITIPDKIRERMKNSKDPVKEGIEIACEIVDRIKEMVSGIYIMPPFEKYEMAAEIIK
RFRV
>A0A5N7UWP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFKPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTIPHVLCGGFTKEETEYLLVDCMYLGINN
ILALRGDAMKGEKYFEPSVGGHKYASDLVKQIHDLGIGEYLHGKIESDTDNSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKFFDFVKQAREIGIDVPIIPGIK
PIATKTHLQMLPQVFKIDLPEALINEVLKCKTNNDVREVGIEWAIKQSKELLDFGIPVLH
FYSMGKSDNILKIGREVF
>A0A139MWQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gallolyticus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADIIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAKAAAGDDAFVLGTVGALRGLKQCDLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEAELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKETNFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDELADLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALEHFNGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A7D4GEP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gallolyticus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADIIQT
NTYAAKRHRLKGYAYDDQVKKINQAGVKIAREAAGDDAFVLGTVGALRGLKQCDLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEAELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKETNFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDELADLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEVVKDDKETCQKLALEESKQLIDRALEHFNGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A7X7UUV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rikenellaceae bacterium|TrEMBL
MKVIDRLTQLKSTLFSFELLPPLKGHTIQTVFNTIDRLVAYNPAYINITYHREEVVYRPD
SRGGTEPVKVRRRPGTVGLAAAIQQRYNIDVVPHLICGGFDMHETEDALIDLDFLGIHNI
LALRGDADKVVGKFEPKIGGHRYAVDLVRQIDAMNRGEYLEKFMDKPKSTNFCIGVAGYP
EKHPESPNFESDLRHLKEKVEAGATYIVTQMFFDNSKFFNFVERCRSMGIEVPIVPGIKP
ISVREHLSLLPKIFGVHIPEDLAVEVEKCADNRQVYELGIEWAIAQTKELKNADVPAIHF
YTMGKPDNIATIAGSVF
>A0A8G1TWS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp. K91|TrEMBL
MSDSTTPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCEAAPHLSCVGATRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLNHFVNKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVNVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPLAVWKELAVQA
>A0A524IYR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccus sp|TrEMBL
MKAGSNLERVFESGKFVVTAEIGPPQSANPEPLVHHAKMLKGYADAFNLTDNQTAVVRLS
SIASAVIVMREGVEPVIQMTCRDRNRIALQSDLLGASALGVRNVLCLTGDHQIFGNEKGA
KSVFDFDSISELQVFDRLRREGKQVGGGEIKDPPKVYLGCAENPFATPYEFRASRLAKKI
AAGADFCQTQAIFDMDLFEKWMDEVRSRGLDKKIHILAGVIPMKTAGAARYMKNKVPGMI
VPNHIIDRMKNAKDSKEEGIRLCVEQIETLKKMRGVHGIHIMAVMWEDIVPRIVEEAGLL
PRPTF
>A0A5E9U2H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. 230|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALSA
RGTTEIAPHMSCIGDDKSEIAELLEYYKTLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
YIREHSGDHFHIEVASYPEMHPQARSFEFDIDNLVNKYQAGANASITQFFYNADSYLYLR
DKLEKRGIDTVAQPLVAGIMPITNSSNLLRFADSCGADIPRYVRKQLTDFGDDRKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLTA
>A0A1I6VEK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. yr668|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTDEMEKILWNSIERLAPLQPSFVSVTYGAGGSTR
ERTHNTVARMVRETGLKPAAHLTCVDASRDEIDAVVQSYWDAGVRHIVALRGDPAEGVGH
AYRPHPEGYASTAELVKGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQA
ITQFFFENEIYLRYLDKVRAAGITIPIIPGILPVQNFKQAANFARRTGASVPYWLAARFE
GLEDDVETRRLVAGAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AAKAAA
>A0A2A2DLK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. PIC25|TrEMBL
MSQERRYSFEFFPAKTEAGHEKLLATARLLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
SEVKVPTAPHLSCVGDSKAELRELLARYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGEHFHIEVAAYPEVHPQARNFESDLANFVRKAKAGASSAITQYFFNADSYFY
FVERVGKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIDSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1F0N8B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC067H01|TrEMBL
MSRQTPSLSFEVFPPNPEVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFITEQAPHFDIIGACYPEGHPDSPNQISDIQNLKRKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAQYIHQATHALFNHQPQGS
>A0A3C0MRS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium variabile|TrEMBL
MSPAPSPESLSTTPPPPSLQVAVSDTLKRGTPGRVPFSVEFMPPRDDAAEARLWSAAEAF
HDLGASFVSVTYGAGGSSRARTERVAGRLAVKPLTTLLHMTLVGHTEEELRGILREFASL
GLTNLLALRGDPPGDPTGEWQGIAGGLSHAVHLIELVRSMPECEDFDMAIASFPEGHYRA
ESIEADTRYTVEKLRAGANYSITQMFFNVDHYLRLRDRLAACDPVHGAKPVIPGLMPITS
LRSVRRQVELAGCELPRDMEELFTKVADGDERKNAAAIREVGIEVTTKMAERLIAEGAPD
LHFMTMNNVRATQEVLHNLGMAPAYGPKFGQDMVR
>A0A4R2S643|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. PP-CE-1G-424|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGLSFEFFPPKSEKMETQLWEAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPVDKVAAA
>A0A3C0JFP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium|TrEMBL
MSVTKKEIASLVSDFSIEVTPASAERVEAFADHLVPGTSINVTFLPGSSFTDTIRVSRRI
HEEGFKPIPHLAARNFESSKALEQSLDNLTSHANVEEVLIIAGGLDSPLGPYHNTMQILG
SGLLEKYAIKKIGIAGHPEGSPDISNSDIDAALYDKNAWARNTDIEVYIATQFCFEASVI
LDWEARIKKLGNTLPIHIGLPGLATLKTLLKFAQMSGIGPSMRVLTRQTKNLAKLVMTQE
PDIVITDLTSRVARAPGSLIKKVHFYPFGGLAKTAAWANSVVNEQIEMKPNKGFNTYID
>A0A8J5IHN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MTGSKADKIIVADTAGVGVISTTGVEVASTAGVELPNTAEMELVNTTERELADTAEVEVL
SDTHSPPGTTNDRVVAGSASFIINKSDDAVFIAFSRAQAAASSSGLGRGFFEPVSQYSST
HKLFALLGRGEEDNGRKPQPMLLQVCMETIMHLTCMNMPMEKIDHALNTIKANGIQNVLA
LKGDPPHGQDNFVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPKAHPDMIQGDEGATL
EAYNSDLAYLKRKVGNS
>A0A8J7HIU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atlanticothrix silvestris CENA357|TrEMBL
MDNNHSYSYNALNCFRKAAQAEEFLVTAEVAPPKGGNPVQMLQMAATLKGRVHAVNITDG
SRAVLRMSSLVASAILLQNGIEPICQMACRDRNRIGLQADLMGAHALGIRNILALTGDPV
KAGDHPDAKAVFDLEAVRLLQLIRKLNQGVDCNEKPLSDEATDLFAGAAVDPQCASWSGL
QSRFERKIEAGAQFFQSQLITDFERLEKFMDKIASAHKKPILAGIFLLKSAKNAQFINRC
VPGVNIPEHIIDRLAQAKEPLEEGMKIAAEQVKIARQLCQGVHMMAVKREDLITPILDLA
GVAPVNLVVAK
>A0A1F8UW75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium GWF2_38_85|TrEMBL
MNIREYIKNNKLIFDGAMGTYYASLYNETTPCELALLEHPERIVRIHNEYIEAGAKAIKT
NSFGANTTVLEGGITLVDDIIEKSWTAALAAVGKAKNKDIYIFADIGYITGDNAEVEYRH
IAEKFLLLGATNFLFETLPDVTNAIKTAEFIKSISPDVFIIISVAAAPDGYTRQGESAAE
LLKLLCEDRNTDTVGLNCVSGPAHLLKFIKQLPSLKKPLSIMPNSGYPTVVGGRTYYPDG
AKYFAEQIARIAQKADIIGGCCGTTPEYIFEAFKSLSSKVLDLTNGYSIPAIHDAITEGK
FLKKLKSGKKVIAVELDPPSDADITPFIKGSGRLKSFDIDVITIADCPVARVRADSSMLA
AKLKREFGIDTVPHMTCRDRNINATKALLLGLGIEGVENVLVVTGDPIPSANRDEIKGVY
SFNSVVLAKYIKLLGEQTGKRFTVGGALNVNAPNFTAELRKAERKVEAGVDFFLTQPIFT
DKAIENLKLAHNTLNAFILGGIIPIVSYRNALFMQNEMSGIDIPDSIVEQYNGLDRETAE
ILAVRISNETIEKIKNFCNGYYLITPFSRVELIGKILKNMKL
>A0A0V1MUA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella papuae|TrEMBL
LMASLEAVELKTTRHDLNSSPKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTPEGL
INLLNRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCVLNFCLLDTMLHITSVQY
NEKTVLSNLERVKKIGIRNILALRGDINDDANVTATDFQYACQLVQFIRSHYGDYFTICV
AGLYL
>A0A2K2ZEH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Formosa algae|TrEMBL
MKVTDHIKQANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFKPPFIDVTTSREEYIYVD
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VVALRGDARKDESYFKATEGGNRFASELVKQISNLNQGKYLHDDIQVEHNYDFCVGVAGY
PEKHMEAPSLNTDLKRLKEKVDAGADYVVTQMFFDNKKYFDFVDKARAIGINVPIIPGIK
PLAVKRHLQILPQVFKIDLPEDLIDAVEACKDNKAVREVGIEFAIQQSKELKAAGVPFLH
YYSMGKSDNIKAIASAIF
>A0A8H5GBY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucoagaricus leucothites|TrEMBL
MKISQKIEQQSKEGKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
ELTSEMVKTCQSLIGLETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPAGKDE
WEAVEGGFVHGIDLVKHIRKNYGDYFDIAIAGFPQHMLLPPDELEQEMIWLKEKIDAGCD
FIFTQMFYDVEVFIKWVHCVREHGITIPIVPGIAPIQTWNGFMRATSLAKTIIPQSFLDV
LEPVKNNDEQVRKLGTKLVAEMCQRILAEPLGIRGLHFYTMNLEKGTKMLLEELNLVPRV
ETIKPLPWRQSLTPSRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGEPKSFSEIANLFSRFCTGDLAALPWSDQKPSSETTIISKQLA
QMNELGFLTINSQPAVNGARSDDKIFGWGPANGYIYQKAYLEFFVSPGLLELLIPHIERD
SNITYYVINRQGDLRTNTHSDGPNAVTWGVFPGKEIIQPTIVEALSFMAWKDEAYELGKQ
WATMYDADSPSHKLISDLMDNSLLVNVVHNDFHDAEAIFKPFLKAGTEFLSKSKPIVNGH
>A0A1F3V794|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionales bacterium RIFOXYC1_FULL_39_130|TrEMBL
MHISEILKSSETSLSFEFFPPNSAKSNNDLFATISNLTPLMPSFVSVTYGAGGSTRQFTH
ELLLKLKKNTKLTIVAHLTCVGHSKTEIKTILEQYLNAGITNVMVLRGDPPKDKAGDFFC
VDGFRYAYQMVEYIKKQFPQIGIGVAGFPEGHPETPNRLLELDYLKQKVDAGADYICTQL
FFDNRDFYDFCERCEIIGIRVPIIAGIMPITSIKGMKRMAELAQGSRFPAKLLRLLNRAD
GDDSVERAGIHWASEQVRDLIDNKAKGIHFYTLNKSNATKTIYESVGLKNALSLQTKGNL
Y
>A0A423EUE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas poae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLATYHPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A5N7BGT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus bertholletiae|TrEMBL
MFPFPLIGGPVKLRPKPFPPRWISLESSFSNYHLSRNIAGPDSGNKMEKITDKIAALPPD
ANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGSTAQRSLELAEICQRQ
LQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNKDFM
FAVDLVRYIRKKYGDYFCLGVAAYPEGHPVDSFQDIQDPKTDLPYLVEKTRAGADFIMTQ
LTYDIEAYTKFENMLRNHGSGVFKTIPIIPGLMPIHSYKILTRVTKLSHVKIPPQILSKL
EEVKHDDDSVKRIGVEIISNLVDGMRDIACPGLRGFHFYTLNLEKTVSFILERCDLIPPY
SEDFDAIEEGDDISAIDGAQLRSLTRRRASSINSLPHNRVIVDKLQVSEVSSKASVSHEA
PATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLH
VPPSVAHRIWGFPVSREDISALFRRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELL
QLINNNGWWTLASQPAVNGVRSDNPIYGWGPPREGFVFQKPFVEFFCPSKDYHSVLKPLL
QSHGHEKLAWFAANIKSDFESSLPAQTSDADPIEMNPNNVNAVTWGVFRGKEIVTPTIIE
EVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNEIKDDLWLVCVVGQDFGAGTEMGSEEE
EDEKKFMWRVLLNAK
>A0A2S4KC54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diaphorobacter sp. LR2014-1|TrEMBL
MSLSTAFPVSFEFFPPKTPEGADKLRAVRQQLYARRPEFCSVTYGAGGSTQAGTFGTVRE
ILAEGVSAASHFSCIGATKDSVRAQLAELKAMGVKRLVALRGDLPSGYGIGGEFHYASDL
VAFIRAETGRDFHIEVAAYPEVHPQARSSDADLQAFATKVRAGADSAITQYFFNADAYLR
FVQDVRRLGLDVPVVPGIMPIMGASQLLRFSDACGAEIPRWIRLRLQGYGDDVASIRAFG
LDVVTHLCEQLRREGVPGLHFYTMNQSAATLEICDRLGL
>H9UED2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium pennivorans (strain DSM 9078 / Ven5)|TrEMBL
MDETNKTEFFAYRFILETLPPRGTNPDKYLAFCKEAVEQGAQIIAVTDLPMGSARVSPIA
PAHMLVEMGLEVLMHFSRTTRNAIRIEGDLIAAHMLGIKNLLILSGDDPRVGTYPFSSSI
EDFSIYDVFKLTKLLNEKGEDLAGLKIFGSFSFNAGGVFSPFEKDLNQTLERMELKMQNG
CQFFVSQPIFNSETILKLFEKSEAEELFRRTKIYIALMVFESFQQLEHYSKVPGVFVPKE
YFRQKNDAHLEQYSIHQCISIIEKLAPYVHGFYLTSTTKKMETIKTISDAVVSQY
>A0A2M8GAC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium CG_4_8_14_3_um_filter_49_14|TrEMBL
MTNTGSNIERILDTGGFVVTSECGPPRGADAGVVRKKGELLRGVVDAVNVTDNQTSVVRM
SSLSACVILKEMGFDPILQMVCRDRNRIALQSDLLGAAALGINNVLCLSGDHQKFGDHPQ
AKNVFDIDSIQLIQAVRRMRDEGKFIGGEEIKGKPVLFIGAAANPFADPFEIRAPRLGKK
VKAGCEFIQTQCIYNLERFERWMAMVRDRGLHEKCAILAGVTPFKSVGMAKYMKNQVPGM
DVPDEMIERMKGVPKEKQTEEGIKICVETIQRLREIPGVRGIHIMAIEWEDRVSEIAKAA
GLLPRPQLP
>A0A3A6P6H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfarculus sp|TrEMBL
MGLKDKLAAGEFAVLAELEPPKGVDVTAFLGHAQRIKGRVDAVVVPEMSNAVMKLSSLGG
CVLLAAKGLETILQVCCRDRNRLALQADLLAAAALGVPNVMAVEGEPPSFGDHHKARPVY
DLELVELLQVIQKLTRGRDMSGVEMEGAPSFTMGATLNTGVLGAVPQELAALDQKLAAGA
EFFVTPPVFDLEQLAGFVKHLAGRPVKIIPNVLLLKSVGMARAIDMHVKNVQMPRLLIER
LKAAPDRVRECVEIAVELIQGVKAAGYSGVMISPLGWEERLPRILEAIS
>W0DGK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermocrinis ruber|TrEMBL
MKIGELLKSEFSISFEFFPPKSPEGEQELFETIKELEALKPTFVSVTYGAGGSTRDRTRR
IVYRIHTETKLTVMAHLTCIAHSKEELLEILQDYKNIGIENILALRGDMPKGDFQAPKGA
CKYAVELVKFIRENFDNFFSVGVASYPEKHPESPNMEWEIRFFKEKVLAGADFSITQMFF
DNSYYYRFVERCHKEGINIPIIPGIMPITNFSQIKKFASMCGATIPQSLVNILEPYAEDP
EETTKRGVEFAIKQCEDLIANGVPGLHFYTLNKSRATLLIYQAIKHLIPPKVLSRLF
>A0A5C0B5W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pigmentiphaga aceris|TrEMBL
MHSPEPVFSLEFFPARDEASSERMLQAATALNELSPRYVSVTFGAGGSTRAGTLAAVQAL
RAQGYDAAPHLSCIGATRAELRDLLAQYRELGVRRVVALRGDMPSGMGPMGDLRYASELV
SFIRAETGDWFHIEVAAYPESHPQARSPDEDLKHFVEKMQAGANSAITQYFFNADAYFDF
ADRALARGITQPIVPGIMPITNYSQLARFSEMCGTEIPRWIRLRLASFGDDRASIRAFGH
DVVAGLCQTLLDGGAPGLHFYTMNQSEPTLGLWRELDI
>A0A2M8GGU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium CG_4_8_14_3_um_filter_49_14|TrEMBL
MNLANKLGKSFVITTELGPVKGALFGESLDKAQEYLPLDGINVHDCPMGNLRINSISMAS
LIQKKLNLEAIPHFTCRDRSLLGTQADLLGAHALGIRYVLVTTGDPPKHGPYPSKPVYDY
NTFELIKLIKKMNNGVDYNDKEFGGNTDFKIACTAMPAARDLDRELEKMEKKINAGADFF
QTQVVYDTNLAIHFSERARSLGKPILIGIMPLKSPKMAKYMKENVEGIDVPDEIISRMEK
EGATGIEIAYNIIRDIYKYIDGIHIMALGDVKGTNQIIEYVKTLMAK
>A0A2G9XM07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacteraceae bacterium CG23_combo_of_CG06-09_8_20_14_all_50_8|TrEMBL
MKVTDIWNSSQRPTVSFELFPARSPKAAENLEKTIDELVALKPDFVSVTFGAGGSTREGS
YQLVKKLKNEKSLEVIAYFTGYGLGPKDIIAVLDDYQGLGVKSVLVARGDPPHEQKDFKA
HPQSLPHASDLLSFIRPRYSFCLGAAGYPEGHIESESKKKDIEYLKLKVDNGAEYIISNY
CYDNQYFFDFIERCKAIGIDVPILPGVMPIYSVKMMETLASLCGA
>A0A359IQV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriaceae bacterium|TrEMBL
MLAAAKGRPLLSFEFSPPKDDAGQDLLHATILELDQLNPDFVSVTYGASGSTRDRTLGAT
QFIKKRVGPQTIGHLTCASQSSDDLRDVVRGYAEVGVNHVLAIRGDMPGGPKAPWVRHPE
GLDNATELVRLVKEVDPAFVVGVAAFPDGHPDKHDLALDARLMLAKQEAGAEFAITQLFF
DPAAYVRLRSTLDAIGCTLPVIAGVMPVTSLGQIERLAEMSGAPLPEAMVARLQAVGDDP
QAVRRVGVDLAVEFCQALLDEGVPGLHYFTFNRARATREIVARLADS
>V6K3E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces roseochromogenus subsp. oscitans DS 12.976|TrEMBL
MLPLAAPEPAPDAAPLLDGQTSPAGTLGEVIAAGGTSYSFEFFPPRGELAERRFWKALRR
VEAVAPAFVSLTYGAGGTSRDRTVRIAERIAAETTLTPVAHLTAVGHSRAELRNIIGQYA
ESGITNVLALRGDPPGDPSGEWIPHPQGVRHAAELVEMVRSCGEFSIGVAAFPEGHPRSA
DPDSELRHFVDKCRAGADYAITQMFFRVEAYLRLRDRVAAAGCPTPIVPEIIPITDHKQL
RRFAALSDAPLPAALADRLERHRDDPAAVRRIGMEHAHAMCARLVAEGVPGLHFITLNRA
EDALALHAAVAPHRPARHPVGA
>A0A1G8UKX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium muleiense|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKNDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A259Q9K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomonas sp. 13-66-29|TrEMBL
MDIPNLSFEFFPPKTPEGAVKLRAARQQLYAHRPQFCSVTFGAGGSTQDGTLHTVKEIAE
EGVAAAPHLSCIGASADSIRNLLRRYRAEGIRRIVALRGDLPSGYGIGGEFHHARDLVAF
IRAETGDWFHIEVAAYPETHPQARTPQDDLRHFAEKMRAGANSAITQYFFNSDAYFRFVD
EAAAIGVDAPVVPGIMPITNASQLLRFSEVCGAEVPRWIRLRLQSFGDDRASILAFGREV
VADLCDQLLAGGAPGLHVYTLNQAAPTLDLLRDLGGR
>A0A1H8UVC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquisalimonas asiatica|TrEMBL
MWQATTAVATTPRGAEALASPRYELIPLTGVMEQASHLPRGATVTVTCSPKHGIDASLDL
AERLAAAGFHAIPHVAARLVTSRSDLQRILDRLAAAGLDDVFIVGGDAPSPAGPYPGGRE
LLEDLDTLSRRPRRIGVPSYPEPHATIPPEQMQAALDVKNALADYTVTQICFDADTILSW
LADQHDRGLRLPVYMGLPGVIDRMKLMGLAMRIGLGASTRVLRRQAGLASRLLGGSTYRP
DALAEALVPAFDGPLAPALAGFHLNTFNQIAETATWAEATAATLHPCPPRDAGQAHTAAG
TPAGYY
>S9Q4B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schizosaccharomyces octosporus (strain yFS286)|TrEMBL
MKIVDLIHGLPKGSTYYSFEYFPPKTTVGLENLMSRITRMSNNMLPLFSSVTWGTAGSTA
SVSVLLSKLLENQHKVPACLHLTCTNVDRKVIDETLETAKNAGIRNILALRGDPPLNSDH
WEGKLSAFEHAVDLVRYIREKYGDYFCIGVAAYPEGHADSNVPELSRDPVHDIPFLVEKV
KAGADFIMTQIFYEPNVFIEFEKTLRNHESGVFRDITIIPAVMPIQSFSILKRMIRLCGC
SIPESLIKRLESVKSDDEAVKSIGVEHAVDMIKTILESTDHRILGFHFCTLNLEKSVARI
LKNSSLLTRRWEQYESQLKDGKTLKNTRRRLSLDETPELHNHVVIPPDDSLKGISASLRN
QPNETALATHRDSLTADAPFSVSEGSGVLGRQANWDDFPNGRFGDPRSPAYGEIDGYGPT
LHFPPQEALRLWGYPVDESDITSLFQRHIKNDIHAIPWIDETVDDETKMISQHLLNVNGR
TWWTVGSQPTVNGAASTDPVFGWGPKGGKVYQKAFIEFFISSKDFEKYLKKWHDNEQITY
YAGNKKGDFLTNAPSDGASAVTWGVYPGREIIQSTIIAEVSFKAWMNEAFDVWAEWAYLY
SKNTATRKLLDHCTNDRWLVSIIHHDYMDNDGLWKALEVA
>A0A0M2WS44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. KBS0711|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVKRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGANAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A7L5ZBV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MSRAREILLSPLGPVARAGSDASRPNVSFEFFPPKTDEAEANLWKAIQRLAPLNPAFVSV
TYGAGGSTRERTHRTVTRILAETDLKPAAHLTCVEASRGEIDEVIADYKAAGVNHIVALR
XDPPGGSGIGGVYQPRADGYAHATELAQAINRVGGFDITVGAYPEKHPESPSIDHDIDVL
KAKVDAGATRAISQFFFDMDAFLRFRDRVRAAGITIPLIPGIMPVSNFKGLQRMGAACGA
AXPDWLAAHFDGLDDDPDTRRLLAASVAAETCARLQEEGFSDFHFYTLNRADLVYAICRV
LGVRETTA
>A0A5B8Z4M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus dafuensis|TrEMBL
MSFLERMKDEILIADGAMGTLLYSYGTDSCFENLNLSHAEQIQQIHEAYILAGANLIQTN
TYAANYLKLQRYGLEEQVKEINTYAVRNARNAIKKDAYVVGTIGGIRGIRPNTVSIEEIK
RSFREQLYCLLLEGVDGILLETYYDLEELEHVLAITRKETDLPIIAQVSLHEVGILQDQT
PISEALSRLEKLGADVVGLNCRLGPHHMLLTLEGIPLPKQAYLSSYPNASIPAYTDGKFH
YEGDSEYFRQSARDFRNQGVRLLGGCCGTTPDHIRAFAKELKGLPPITEKKVKNSKKIII
SNSSATLREDPPLQDIVKERASIIVELDPPKKLNTDKFFEGAKALENIGIDAITLADNSL
ASPRICNSAIGYRIKKEIGTRPLIHITCRDRNIIGLQSHLMGLHTLGLHDVLAVTGDPAR
VGDFPGASSVYDMSSFELIQMIKQLNAGLSISGKDLGEKTAFSVGAAFNPNVKSLDRAVQ
RLEKKIEYGADYFISQPIFSEEKLIEVHGAIKHLKKPLYIGLMPLTSSKNAEYLHHEVPG
IKISDSIRARMAELKDDSILAAREGIAITKSLIDAATELFNGIYLITPFMRYEISVELSA
YAHETSAKISRRRQNAEVTIN
>A0A6A6V5G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporormia fimetaria CBS 119925|TrEMBL
MEKITDKINALPDGAEYFSLEFFPPKTATGFHNLQERLERMTQALRPLFVTVTWGAGGST
ASKSLELAELCQRQLGLTTCLHLTCTNMNRSLIDEALEQAKVLGIRNILALRGDAPRSDE
YRDESQPPEQDSNKDFTYAADLVRYIRKQYGDYFCIGVAAYPEGHSDESHPEHQDPLADL
PYLVEKTKAGADFILTQLFFDVGAYDRFEKMLREHESGVFKTIPIIAGLMPIQSYQILRR
TTKLSHASLPVDLLERLDAVRGDDELVKKVGVQIISEIVDHIKRRPGASKKGFHFYTLNL
EKAVSHILEDCRLIPLAYSTDTEAVDTSFDVGDLLPPEGALSRVRRRLSSVGSSPHNRFI
VSHPSQSSSHGFETSDHEAGLLSAAINTRAHTLAISEGEGSLGREAVWDDFPNGRWGDAR
SPAFGEIDGYGPTLHVSTPQALKLWGHPVEVSDISAVFRRHIEGELEALPWSEEGLSPET
STISKELLAMNAKGWWTVASQPAVNGAKSDDPVFGWGPKNGRVFQKPFVEFFIPSADWKK
LKPKLDAHEQVTYFAGNEAGDFEATDEESVNPVTWGSFVAKEIVTPTIIEAVSFRSWMDE
AYNIWKEWQRIYPSKGRTSQLLEEVRKDVWLVNVIWGDFLDPNGLWELLLE
>A0A8H8RL00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnellula occidentalis|TrEMBL
MHVSQMLSEAERSKQPKFSFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLA
QLTCEMVSVAQSQYGLETCMHLTCTDMGKEKVNEALKETYKAGCTNILALRGDPPRENEK
WEATEGGFRYAKDLVKHIRDTYGNHFDIGVAGYPEGCDDQDDLELLLDHLKEKVDAGATF
IVTQMFYDVDNFLDWVRKVRAKGITIPIVPGIMPINTYASFVRRCNHMNCSIPPKWMEAL
EEVKNDDAAVRNIGTGLVAEMCRKILDSGLIHHLHFYTMNLAQATRMVLEDLNLTPSDER
PLKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQEWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEQNRKLWGEPTSIKDIAEIFVKYLEGGVDSLPWSEAPITSEADSIKADLI
GLNKRGFLTVNSQPAVDGVKSSDPVYGWGPANGYVYQKAYLELLVSPQIMDELVQRIERD
PDLTYYAVNKAGELKSNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMD
WAHCYSNLSPSRNLIQNMMENWFLVNIVHNDFHQTHGLFRLFDELSVPSIDKPFEVESKN
GIETNGVNGVNGSKSDGSENIPLTNGA
>A0A4Y8NG06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ICN441|TrEMBL
MALGTASTRTDRARTVRELLATDKTSYSFEFWAPKTEKGERNLWNALRRVEAVQPSFVSV
TYGAGGSTRAGTVKATQQIAADTTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPDGVRYAAELVRLIKESGDFCVGVAAFPEMHPRSRDREADIGHFVD
KCRAGADYAITQMFFHVEDYLRLRDSVADTGCETPIIPEIMPVTSVKQIERFARLSNASF
PAALEERIRAVADDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQQS
>A0A1I0XUQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium swingsii|TrEMBL
MKVTQHIENAQGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEYKE
LPSGLLEKKIVKKRPGTVGICAAIQNKYRVDAIPHILCGGFNREDTENLLIDLDFLDIDN
VVALRGDALKNEIYFKAEKAGNQYASELVTQIANLNKGIYLDEDLQNSSSTNFCIGIAGY
PEKHMEAPSVDSDVHFLKQKIKNGAQYIITQMFFDNKKFFDFVAKCRAAGITIPIIPGLK
PIATKKQLNLIPHRFSVQLPDDLIMAVVKANDNDAVKQIGIEWCTEQSKELVAAGIPVLH
YYSMGKAENIKAIAREVF
>A0A2A9NLH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amanita thiersii Skay4041|TrEMBL
MKISKKIQQSTSDDKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPKEKVDIALREAKQHGCRNILALRGDPPMGKEE
WEAVEGGFIHGIDLVKHIRNEYGDYFDIAVAGFPQHMLLPPDECDQEMQWLKKKIDAGVN
FIFTQMFYDVQIFIDWVRAVRAAGIMIPIVPGIAPIQTWNGFMRATSLAKIIIPQSFMDA
LEPHKNDDEKVREIGTKLVADMCRQILKEDLGIRGLHFYTMNLEKGTKMLLEELSLVPRV
ETIKPLPWRQSLTPNRRSENIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKENALKLWGHPITFEEVASLFARFCQSDLKALPWSDQAPSRETAIIAKQLA
QMNQLGFLTINSQPAVNGVRSDDKIFGWGPSNGYVYQKAYLEFFVNPTLLSLLLEELDKD
SNVTYYVINKRGDLRTNTRSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAYELGQQ
WALFYEPDSPSRKLITDLMETSYLVNVVHNDYHDPDAIFKSFLKVGSDYLAIKSGSNAIN
GHS
>A0A5R9ECJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces marianii|TrEMBL
MALGTASTRTDRARTVRELLATDKTSYSFEFWAPKTEKGERNLWNALRRVEAVQPSFVSV
TYGAGGSTRAGTVKATQQIAADTTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPDGVRYAAELVRLIKESGDFCVGVAAFPEMHPRSSEWQTDIGHFVD
KCRAGADYAITQMFFRVEDYLRLRDSVAEAGCETPIIPEIMPVTSVRQIERFAQLSNALF
PAELEQRIRAVADDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQQS
>A0A235CAZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanimonas baumannii|TrEMBL
MGFHSARHVEALNQSLSELNGDINVSFEFFPPNSEAMEQTLWSSIERLKTLQPKFVSVTY
GANSGTRDRTHKVIKDIQDKTGLIAAPHLTCIDASRDELRGIARDYWNNGIRQIVALRGD
LPQGMEKPDMYAADLVSLLKEEADFDISVAAYPEVHPEAKSAQADLLSLKRKIDAGANRA
ITQFFFDVESYLRFRDRCATVGIDAEIVPGILPVSNYRTLLKFAGFSNVRIPAWMHQRFE
GLDDDQNTRNLVGASIAMDQVRVLSREGVKDFHFYTLNRSELTYAICHSLGVRPQELVK
>A0A371QC95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. NM|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQITDIQNLKKKVYAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>G3Y2A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a / NRRL 328 / USDA 3528.7)|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVEQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDTSSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A7C4RSZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatirhabdium butyrativorans|TrEMBL
MDDPKVNLKSGSNLEKVLKAGHFAFTGECGPPKGANIEHLREKFHHLKGVVDAVNVTDNQ
TAVVRLSSWAASAIMVQEGVEPNFQMVCRDRNRLAMQSDILGVYTLGIRNMLCLSGDHQK
FGNHPQAKNVYDIDSMQLIALAKKMRDEGKFFNDDPIDVPPKLFIGAASNPFAEPHAFRI
HRLAKKIAAGADFIQTQCIYNMERFREFMHQAVDMGLTEKCFILAGVTPMKSVGMANYMA
KQVPGMDVPDSLIKRLKGVEKSKVAEEGIRFCLEQIEEFKSMKGVAGVHLMAIEWEHRVP
EIAERAGLLPRPVVE
>T0N511|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon Gpl|TrEMBL
MQISNFQSKQKILKSVEIVPKRNENIDDLLAAREIFSDIADMVTAPENQMGRPGIDPLMA
LYIMTHGTNVIAMPHVTPRDKNTLYISSQILTSEKLGINHFFVIGGDPISGNLGREVREM
DTNETIRHIRKFSREQERDKEAIIGAALNPYRNSEEEIVRSKIESGATLFISQMCYNSEP
FKKKWIRQRKFKLFLGFMPILKKSNIESLSKMGVLLPEGLKSIIANSENLRDTSLKLIDN
LVSDMKGYIDGVHIMPIGNNEIAKEIMEVL
>A0A652K1L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. adm13(2018)|TrEMBL
MALGTASVRSDRARTVREILASGGTSYSFEFFAPRTEKGEQVLWNAMRRVEALGPSFVSV
TYGAGGSTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNVLGQYADAGIRNMLAVR
GDPPGDPLGDWIEHPEGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSLDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSAVKAGCETPIIPEVMPVVNVKTLDRLPLLSNAHF
PADVKERILAVKDDAAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTAIEIYENLGL
HQQS
>E3G4T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter lignolyticus (strain SCF1)|TrEMBL
MSFFHANQREALNQSLAELDGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIVPGILPVSNFKQAKKFADMTNVRIPAWMAKMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A6J4IPR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Acidimicrobiales bacterium|TrEMBL
MSAGVSGRAFEWICEIEPPTKPDLMHVRHQIGVLSKIASAYLIPDNHVGRATVSSVAVAH
EVDRMGGRSIACLNARDRNALGFQRDLLTGAAYGVDEFLFVYGDAPVSGARTGQLTVRSM
IEDLRRFSQAHQGHADGFRAGVTTRLQPLPAWKHEADFLFVQVSFDVEKLLAWRDTIEFD
GRVYAGVMVLPSAPMARKLAAAIPEITVPARWIDAIEHDRHAGVELACQLAESIGDTGAF
DGVHFIPGVRYRETAARLERDSRRH
>A0A0F0DGJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 21|TrEMBL
MSQKERRFSFEFFPAKTEAGHEKLLATASQLAAKKPDFFSCTYGAGGSTRDRTLTTVLQL
DGDVKVPTAPHLSCVGDTKPELRALLAHYKDAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRAETGDHFHIEVAAYPEVHPQARNFEDDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAEKLGVSIPVVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDIASIQAF
GEQVITDMCERLLEGGAPGLHFYTLNQAEPSLALWNNLKLPR
>A0A7S6ZY68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. H23M47|TrEMBL
MIATSFEFYPPKTDEQRKQLDRTAGRLKSATPDYVSVTFGAGGSTLSHTPETIERLQGHH
ALEAAPHISCMGGSREEIRAQLQRYMGMGARRLVTLRGDLPSGMASPGDLRYASELVEFI
RDETGDHFRIEVAAYPEMHPQARDAHADLKHFIGKAKAGADGAITQYFYNADAYFRFVDD
VRAAGVDIPIVPGIMPISNFSQLRRFSEMCGAEIPRWVTQRMLAYGDDVASVRAFGTDVV
AQLCQRLIDGGAPGMHFYTLNLARPTLAVLARLA
>A0A5A9GRZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum lipoferum|TrEMBL
MTAPTSALPSISFEFFPPKTEKMEQSLWQSIRRLAPLSPSFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGRYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPEAHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDAYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPAKLAETFEGLDD
DPETRQLVAATVAAEQCQALQAQGVNDFHFYTLNRSDLTIAICRMLGVKAKAAPAAAVVA
G
>A0A3S3RJY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dinothrombium tinctorium|TrEMBL
MFIVVKRALKSNNRMGRGLKSFASNSNCDINQFNSQLRSDAFTLAQRIKKYNESKDVPFF
SMEFFPPQSADATINLISRLEKIREANPMFCDVTWHGTGTPDGKAQTSSLNVAGMMLNYC
GITAMSHVTCVSVDKNSLHLYLERAKELGVRNVLALRGDKISEKNLKQRDFTYAADMVKY
IRQNHGDFFTIGVAGYPCKHPEAESYEKDIQHLKEKVDCGADFIITQFFFESDSFIKFAK
DCRQVGIKVPISAGIMPIQNYSSLKKIIRISGIEAPKHILDTVKENAAFTTRVQKYGIDL
ATDMCKQIIKSGSADGLHFYTLNNENSSVAVLKNLGLWHTGVQRPLPWLHIPSEKRFHEE
VRPIFWRNRTKSYLFRTSEWNIFPKRKWSEYSSQSYKTLDENYYMCLGRTSYSPNELLEM
WGKELSSEKDIWDVFYNYVSGSINKYGIKVTRIPWSEGELNPETNLISEQLARINARGFL
TINSQPNINGADSTDPIVGWGASGGYVYQKAYLEFFTRREYAQILRIVLDKYPWVNYHMV
NCDGKENYTNSSKETPIAVIWGVFPGAEIVQPTVVDPVSFMVWKDEAFSLWRESWAKLYP
EDSQSRNVLDDVVNNYFLVNLVDNKFKESCCLWNILDETYETRGK
>G9ZFZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cardiobacterium valvarum F0432|TrEMBL
MNLVARMCAENGPPVMPHLTCVASTEAEIRTLLDDYRALGVNRLMALRGDMPSGAFENAG
FTTATQLVSYVRQLWGEDARICVAAYPEVHPRARTPAEDLHAFREKVMAGATDAVTQYFY
NADAYLRFRDDAQALGVEIPLVPGIMPISNYVQLSRFSDACGAEIPRWLRKRLEALQDDI
PALCDFGADMVAQMCERLIAEGVPALHFYSMNRADLIREICKRLGWC
>A0A2G9YHL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG23_combo_of_CG06-09_8_20_14_all_41_10|TrEMBL
MTFKEKLQAGKFLVTSEIGPPKGIETKQLLEDAELIRTRVDAINVTDLQSSVMRLGSLAV
CSILKQHGFEPIFQMACRDRNRLALQSDLLSAAALGIENVLILTGDHTTLGDHPNAKPVF
DLDSVQLLQAARRLQEGSDMNENKLLGASPKFCLGAVVNPGADPLEPQIMKMEKKIAAGA
EFFQTQAVYDLKVFENFLNKTKHLKTKIMAGIVLLKSAGMAKYMNKNVAGVFVPDNLIKE
IEGAQDKVARSVEIASRLIKELKPICDGIHIMSIGWGKVVPRVLDASAL
>E9S7Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus albus 8|TrEMBL
MKTCDIFKQKTTLSFEVFPPKSDTPIDSIYSTIDGLAPLKPDFISVTYGAGGSGSNATIG
ICEMIKEKYGIEPVAHLACINLTREKVLFELAQMRAAGIENILALRGDINPNVPPHEDFR
YAAELIELIKESGDFNILGACYPEGHPEAPNMVEDIRHLKEKVDAGCSQLISQLFFDNED
FYAFREKAAIAGIDVPIEAGIMPVTNPKTIARMATLCHAKLPKKFLTIMSKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIATKICSAVQSLFK
>A0A1B1PR80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger sp. CCB-MM3|TrEMBL
MTRPDISFEFFPPRNIEATFRLWDTVQALSPLDPRFVSVTYGAGGTTRELTRDVVATLHK
NSGLKVAAHLTCVDATREETLAIARQFKEAGVNDIVALRGDPPKGASGFTPHPEGFNSSI
ELIEALREAGDFTIRVGAYPDKHPEAPTATADVEYLKRKFDAGASEALTQFFFEAESFFR
FRDECEKAGIDKPIVPGILPIENWKGARRFAEATGTKIPAWVIEAFEKAERDDRQDLLAT
AMCTELCNELIEGGVDKLHFYTLNRPELTRDVCYALGVTPDNKLENVA
>A0A651FPU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrionales bacterium|TrEMBL
MKIRDLLKEPVRSKISLEFFPPKDRANWPKFFNTVQKLQAVDPLFVSVTYGAGGSTQAAT
LEIVTTLKRDFGMEPMAHLTCVGASSQALRSFLDDLTRAEVRNVMALRGDPPQGESKFTP
SDDGFQYASDLVQFIATHYPDIGIGVAGYPEGHPEAVGLKEDLDFLRMKLGLGGDFAVTQ
LFFDNTVYWDFERRARAVGVDKPILPGIMPIFSLKFIQRITSMCGSSLPSGFMRDLEEAD
AKGGDAAVQEVGMAHAAAQIQDLLDNGAPAVHLYTMNRSDGCLRILEQVRC
>A0A3R6F2R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MLDVRKLLAQRPLLFDGGMGTYYKAKPGQECEQANLTDPEGILAVHRAYLAAGADAIKTN
TFSLPRLAAAQQPGWEQLADAGWQLAAKAAGETGAAVFADLGPAPDTENLPAEQVYLAVA
KRFALLGARNFLFETLSAEDGVLEAIRALKQTVPEAFVLVSFAVLPDGYTREGRYCAELV
RRVAQSGVVDAVGLNCVSAPGAMRALVQQLGDAGLPLSVMPNAGYPVVARAQVRYQGKPE
YFARELSRLASEGVRILGGCCGTTPQHIAALRTALDALPEALPAAPAAKPAAAAKPAVET
DDAFLRKLRTGQRVIAVELDSPKDADLTAYLEGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGMNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPAPITVFGALNLNARNFEVELRRAAEKLENGMSGFL
TQPVLSAQAVENLKKARETLGERAKILAGILPVVSQRNAIFMENEVNGIHVDDAIIQRFE
GLDRAAGEELGLEVSVQAAKAAVPYADGFYLMTPFNRVALMERLIARLRTEVTG
>A0A7K4FZB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosarchaeum sp|TrEMBL
MAVIYEINPPKIPEGIKASNEETNSLLSKLVQRVSDISMLCDGIHVTDSVLGTRRVSALT
TGKILKTNHPNLQITISMRVRDKDMDSIKQIVQESIDLKLDGILVLKGDPSKENPTDSGL
IPSHVVKQLNELGYGKKINFFLSLPSNPNFEKIQKKITAAPKGFMTQVIHSTEQVQRISN
KLRPGGFRIIPCVLLPTEKNENSAKFLELDWSGYKENPANFIRQIHSIAGDVLITSPNDF
TFAEETLKKI
>B9MN09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldicellulosiruptor bescii (strain ATCC BAA-1888 / DSM 6725 / Z-1320)|TrEMBL
MKKSFREFLKEQAIVIFDGAMGTQLLLRGFSVDFPLEWANVANPELVKQIHTDYILAGAT
CVETNTFGANECKLKVFGFENEVERINRSAVRIAKEVAENKVYVIGSVGPLGKPVGNGFE
IDDKKAKDVYKRQLYFLLDEGVDAIIFETAASTHEVQIAIEALKELNDKIPYIIQFSFTK
ELSTVYGEDIYRVIEFLKSTNADVVGLNCGNGPQKTLEALKIFSQHLKGPFSVQPNAGYP
QLIQGRPVFSTSANYFASFVPEYIKLGAKIIGGCCGTGPEHIKAVKEKIKEVSPSIEIEV
VERKEEQKAVLKDTPSELSQKLGKKFIFTVEISPPKGIELEKTKEGVKLLKEAGADTVNI
ADSPMARVRISPIALAHILKEELGMESILHFTCRDRNLISLQSELLGAAALGVKNVLALT
GDPPSIGDHPQAKPVFDVNSEGLVLILSRLNNGTDYMGNPIGKATNFTIGVALNLNADDL
GKEIEKLKHKIENGAHFIETQPIYEPETLERFFEKVDFKLPPILGGILPLRSPRHAEFLH
NEVPGITIPDKIRERMRTSKEPAKEGVEIACEIVEKIKHMVSGIYIMPPFEKYEMAVEII
RNFKI
>A0A329U8H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MIDVRAHLARKPLLFDGGMGTYYKAKPGTECEQGNLLDPAGVRKVHREYLAAGAEAIKTN
TFGLPRMAAARQPDWQALARAGWKLAAEAAVETGAAVFADLGPAPDTEAAPAGSIYTAVA
RCFVEQGAKNFLFETLSSDAGVLEAVQAVKAQVPDAFVLVSFAVLPDGYTREGMYSKDLV
RRMTESGIVDAVGFNCVSAPGAMRTLVQQLGSTALPLSVMPNAGYPVVTRTQVKYQGKPE
YFAKELARIAAEGVRILGGCCGTTPAHIAALRAALDSLPAVEKAAPAVQVSTPEAPTVEK
DDAFLRKLNAGKKVIAIELDSPKDADLTNYLAGAKRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGLCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPMTVFGALNLNARNFEVELRRAGEKLENGMSGFL
TQPVLSEQAVENLRHTRETLGERAKILAGIMPVVSQRNAIFMENEVNGIHVAEDIMEAFA
GLDREQGEALGLEISLKMAREALPYADGFYLMTPFNRVALMERLIARLKTELLQEQ
>A0A8E3SPG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium KGMB03038|TrEMBL
MKIRDILKETTPHISFEVFPPKTEAAFESVLNATDKIAALNPSYISVTYGAGGGTSANTV
NIAAHIKDDLDTVSLAHLTCVSSTREHVHKVIDELKERGIENILALRGDIPKESEFPLPN
QYRYASELIEEIKKEGDFCIGAACYPEGHVEAPNRKEDISHLKEKVDKGVDFLTTQMFFD
NNIFYNFLYRVREAGITVPILPGIMPVTRGSQMKTICEMSGTVLPQRFRDVLDRFGEDPA
AMKQAGIAYATDQIIDLFANGINHVHVYSMNKPEVAAAIMRNLSEIVKH
>A0A7W7ITQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium nitrogenifigens|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFTPKAGGNHYAIDLVKQINNLNNGKYLHELMDVDNKADFCVGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAVQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A5N5N853|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coniochaeta sp. 2T2.1|TrEMBL
MDKITDKIAALPPGQDYFSLEFFPPKTAMGFSNLRDRLDRMSRALRPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRKLIDQALQDAKALGIRNILALRGDPPRRSE
YRELNDPEPEDGEEEFVWAVDLVKYIRKNHGDYFCIGVAGYPEGHADESHPLGQSLEHDL
PYLVEKVAAGADFIMTQLFFEIKAYDHFETTLRQHPSGVFKDIVIIPGLMPIQSYQMIKR
TTKLSHAQMPDVIMERLDSVKGDDERVKMVGVDIVAELVEKIREIKSRTSSGPKGFHFYT
LNLEKAVSFIVERTNLIPPSTPFEDESAIADDLPPTSIPELHVNGSSSSQILSLKNLSRR
QSSVGSDPRNRVIVSGRSGGVSNPDYEATALDASIPAEPINTRANTLAISEGEGVLGREA
TWDDFPNGRWGDARSPAYGQIDGYGVSLHVSVAQAINLWGTPTTPEEINQLFIRHLRGEL
SAIPWSEEGFNAETAAIRDQLVKLNERGWWTLASQPAVNGLKSNDETFGWGPMNGFVFQK
AFVEFFIPAADWAALEKKLTRPGMRDTVCFYAINARGDFVSSDTLPTTNVDAGDGATEEK
AEDGAREPSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFSIWGEWAKVYGRGSESQK
LLDRIREESWLVNVIHHDFVDKDGLWDLLLKD
>A0A8B3J3N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas salmonicida|TrEMBL
MGFHSARQVEALNQSLADLSGDIGVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDAGRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKDPA
>A0A4R3G582|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK376|TrEMBL
MALKTESSRRDIRISFEFFPPKSDEMEAQLWETVPELAAWQPEFVTVTYGAGGSTKEPTL
AAVRRMISEKRLPTAAHLTCVDASQDEVKAVVEEYRAAGVRRIVALRGDPAAGIGSAYTP
HPQGFSDTADLVRMLVDYGDFDISVSAYPEKHPESPDMAADIATLKRKADAGATRALTQF
FFENDAFERYLERAQAAGVTMPIVPGIMPIQNLTQLKRFARRCGSTVPAFLDDRFEGLDE
KPEERAEVAADVAAEQIEDLIRRGIREFHLYTMNRAPLIGAVLERLGFRRDTDIQAAGAA
A
>A0A7S8HAG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kaustia mangrovi|TrEMBL
MRDDEVKTTNGQAEPEREFRVSFEFFPPKNEAMERSLWEAIKKLEALDPAFVSVTYGAGG
STRERTHSTVTRILKETGLTPAAHLTCVGAERGEVDDVVRAYDKAGVRNIVALRGDPPEG
VGSAYAPHPGGYENAADLVGGIRKIADFDISVAAYPEKHPESPDWETDLAMLAAKVDAGA
DRAITQFFFDNSAYFRYLDRVRARGIDVPVVPGIVPIVNFKRVAGFAGKCGASIPPELAA
RFEGLDDDPETHALVAAAVAAEQVAELRDQGIDQFHFYTLNRAELVYAICRLLGLGTKTE
KAAA
>A0A2N5EW73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. QC2|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFENDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISTMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>W1VD35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces urogenitalis DORA_12|TrEMBL
MSPSLAQPYTRHVAPKPSPAAIAPSLTPAEPARPSLSLELFPPRPGRYASQTWGALDRLL
AARPDFVSVTYRPRFITTAGGPTAAAGSPTRLHVVREHNPSEDVVAHVIATSRVPLMAHL
TCLGYRKANVVEIVRLFLDMGVRRFLALRGDPPRGVAAEDVVGELRHADQLVRVIREVEA
EYFDDGARHVQVAVAAYPAAVDYAREIGVLAAKQAAGADLAITQVFYESEDYLALARAAS
YCGVTMPILPGIIPLTDLRRLTRLEDLTGVSVPTRLSQTLTSRQGASVMTAGIDATLQLA
GDLIEGGAPGLHLYTFNRTRPALDVISQFRLGGVLDGARPDRVTQREIARAYINAVPGSG
ARLTGRMPVAARP
>A0A202C5Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium mucoviscidosis|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICASIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHGSAMELVHQINDLGRGKYLHNQDEICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGI
KPIATKKHLKVLPQIFKIDLPEDLINEVENAKNNEAVKQIGIEWAIAQCRELLEFGVPVL
HFYSMGKSDNIKKVAGALF
>A0A0J0YS52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria arctica|TrEMBL
MTSNQKKLSFEFFPTRTPEGRAKQVITRKQLSQYNPEFFSCTSGAGGSTKEGTMQAIKDI
LSEGVPAAPHLPCVGMQPGEVINLLNEYKDLGVRHVVALRGDIPSGVGAGMSGLRYANEL
VELVKNEFGNHFHIEVAAYPEYHPQARSAEDDINNFVRKAKAGADSAITQYFYNADAYFR
FVDDVHGRGVDIPIIPGIMPIASFSKLARFSDTCGAEIPRWLRLKLQSYADDTAAIKALA
LDVVTEMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>A0A5C7WG77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niabella sp|TrEMBL
MKVTDHISQAKDTLISFEVLPPLKGKGIEALYKHLDPLMEFKPSFINVTYHRSEHVFKKR
ADGSFEKVVVRKRPGTESICAAIMNKYNVDTVPHLICGGFSINDTEDALINLRYLGIDNV
LVLRGDAAKNETAFEPEPGGHKYASDLLKQVANLNAGIYLEDELKGTHKTDFCIGVAGYP
EKHFEAPNMDTDLQYLKAKVDAGADYIITQMFFDNAKFFAFEKACRAIGIKVPIIPGLKP
IYTKKQLTVLPKTFSIELPSELSKAVSQCKTDEDVEKVGTEWLLNQSKDLKKAGVPVLHY
YTLGRPFMVAAVVKELV
>A0A8G8Q8K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT2-18-2|TrEMBL
MPHTSDPACRKIPFSFELYPPTSDAATSVLHATIERLAAAGPEFIAVTYGANGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSNAEASQLIREFLDAGVRSFLALRGDPPEGIREGEAF
LGDLGSAAELVQLIHRVQAERVPYREAVIPGLPAARTIKREREKVRIAVAAFPNGHPRSR
SATQDIDTLLAKQAAGANLAITQLFFHADHYLSFILRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRQATELARELISGGAPGLHLYAFNQHE
TVLAVLDGCGLLTPTLPSSALPAPHPVKENP
>A0A7T6VNN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKIIDLFKEGKQVISYEVFPPKTSAGIESVKVATEEIAKLNPGFISVTYGASGGTSDYTV
DIASNIQKAYNVTSLAHLTCVTSNKETIINQLEKLRDNNIENILALRGDLPEDMEKFRSR
DYNYASDLMKDINSFGDFCIGGACYPEGHVESERLIDDIETLKNKVNMGCEFFITQMFFD
NNILYNFLYKLRDAGISVPVIAGIMPVTNPKQIKRITELSGTHLPQRFKTIVDKFGHNPK
AMAQAGIAYATEQIIDLYANGVNGIHVYTMNKPEIARRINNNLSEIVNN
>A0A087D9S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium saguini DSM 23967|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGIEDLKPDFISVTYGHGTHSDRTATARIANTIV
NEYRIPAVAHLTALYSDKTKIDEALDMFENAGVNTVLALRGDYIDGEQVVGAFEHASDLV
AYIRERKPNFTVFGACYPEGHYQAESLDKDIEHLKIKVDAGVTHLITQLFYDNDDFYRFR
DKVRAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPEHLDALLNRWEGNTEALHNAGIL
YASEQIADLVAHGVDGVHLYTMNHPATTRRIWRNVKSLFNE
>A0A8J6I656|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporichthya sp|TrEMBL
MTTGSDPRAAGSTLGATIRDLLAAGGRSYSFEFFPPKTDEGERTLFETIRQLEPLAPTFV
SVTYGAGGSTRDRTVRIVERIATDTTLTAVGHLTCVSSSRADLRSVIGTFAAAGIRNVLA
LRGDPPGGAGTPWEPHPDGLEHADELVRLLRELGTFCVGVAAFPEGHPESSDLDSDAKHL
ALKAAAGADFAVTQFFFDADDYFRLVDRAAAHGCTIPILPGIMPVTNLGQIQRFSELSGA
VFPPALAERLQTVADDPAEVRRIGIEVATELCSTLLDGGAPGLHFYTLNRSTSTLEIYRA
LGLAPTTARSQG
>A0A7C7EPN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MRIADKFNKGRVVFSLEVFPPKKESGVETIYNTLEQLSDIKPDYISVTYGAGGNGGVQQS
CEIAANIKLKYGIEPVSHLTCVNNTKDEIIKVLADFKTKGIQNLLALRGDINPDIPRKTD
FVYASDLVSFVKTYDKSFGVAGACYPEVHMEAKNEVDDIFNLKKKVDAGADNLVSQLFFD
NEVFYRFIERAKIAGINVPIQAGIMPVTNKKQIERMVSMCGASFPSKFSRVIQRYGDNPQ
ALRDAGIAYAVDQIVDLIANGVDGIHLYTMNNPYVAKTIAKSIEKLL
>A0A4V6ILG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoluna butyratoxydans|TrEMBL
MKSGSNLEKILAAGHFAFTGELGPPRGSNVEHVKEKAQHLVGHVDSVNITDNQTAMVRMS
SWAAALLVNEMGLEPNYQMVCRDRNRLAIQADVLGASAMGIRNMLCLTGDHQMFGDHPNA
KGVFDIDSIQLINTVKTMRDEGTFLSGEEIDVPPKMFIGAAANPFADPFEWRVHRLAKKV
EAGVDFVQTQCVYNMDKMREWVKQAVDMGLTEKVHILAGITPMKSVGMAKYMKNKVPGIE
VPDELIKRLQGAGKGKVAEEGIKIACEQIEEFKEMKGVDGVHLMAIEWEHRVPEIAERAG
VLPRPVVE
>H1DHD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odoribacter laneus YIT 12061|TrEMBL
MKITDILNRKAKPFATFELVPPLKGSDINKLYKAIDPLMEFKPPFINITFHRNEIEFRQK
ENGTFEKITVTKRPGSVAIAAAIMKRYQLEVVPHLICGGASKYTLENDLIDLNFLDITNV
MALRGDAIPGQKYFIPEVDGHKYSCDLVSQIHNMNQGKYLDETLTNAIATNFCIGVAGYP
EKHYEAPNPETDIMNLKRKVDAGADYIVTQMFFDNNRFFHFVDKCRTAGITVPIIPGLKP
ISTHTHIEMLPRTFSIDLPEELMKEVRKCKNDQEIYQVGIEWCITQSKDLLAHGAPAIHY
YTMGKADNIRTILKQTF
>A0A1H2XUX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiocapsa roseopersicina|TrEMBL
MPLQSQQTPTYSVELFPPKTPEGMEKLKHEIAELNSVSPSYVSVTYGAGGSTRDRTFETV
DWLRGHHIETAPHIACVGSARTEIREILGRYREQGIRRLVALRGDLPSGMGGGTGGDFRY
ANELVTFIRDEFGDTFKIEVAAYPEYHPQSGSPERDLANFKRKVEAGADAAITQYFYNPD
AYFAFVESCDRVGVTLPIIPGIMPITNYTQLARFSDACGAEIPRWVRRRLEAYGDDVESL
RAFGHEVVLKLCRRLIDGGAPGLHFYTMNQSGPTLRLWQDLALPRPA
>A0A3D5UGU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKIKDKFKVKNPLVSFEIFPPKADYPVDTIYDSIDELYSLYPDFMSVTYGAGGSTKDRTI
EISSHIQNKYKLTSIAHVTCISSSRNEINNIINLLKKNNIHNVLALRGDYPKDAAYTPPS
DGFKNSVELIEYLRKNTNLCIGAACYPEKHPEAYDLNADIDFLKRKVDAGADFLITQMFF
DNELFYDFYDKVHKKGINLPVITGIMPILNKNQIKAIVNLTGNIIPVKLRRILDKYENNP
VALNEAGMSYAISQTIDLLSWGVDGIHIYTMNKPSTAKKILDSISAIRGVLTNESKSS
>A0A3D1LF87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKITELFQNREFVVSAEVGPPKGIHIDGMVEEAKKYLTGVHFVNVTDNQSSVMRLGSLAT
CKVLKDAGLNPIFQLTCRDRNRIALQSDLLSAAMLGIDNILCLTGDHTKLGDHPQAKPVF
DLDSVSLLYAASMLETGKDLGGNELVGEAPKFAKGAVVSPCSDSVDAQLVKMERKVKAGA
EYFQTQAVFEPEKFIKFMEAAKQFGKPVQVGIIIPKSAGMCKFMNNNVAGVHIPDELIAE
LQADKEKTKAGITGVEIAARIIRECKPYCQGVHIMSLGWESKIPALLEQAGL
>A5UEW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae (strain PittGG)|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DYDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A316PFK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKISQLFKNKNDKPIISFEIFPPKKEEAFENVGIMLKELSYLEPKFISVTCGAGGSSNRN
KTIELASKIKNEFNIESMAHMTCISSTPDSVLEEVKAIQDEGIENILALRGDIPKEGFEP
EKASYSHAFELIKEIKTNSELCVAAGAYPEGHIECDDFNKSIEHMKIKEEAGADFFVSQL
FFDNRYFYRFFEAAEKAGITVPITPGIMPMMSKSQISNMIFMCGASLPSEMVRILYKYES
SPDDLLKAGIEYAGRQISDLVKNNTCGIHLYSMNKPEIAKQLLEYV
>A0A4Q4UZM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus sp. MG133|TrEMBL
MQIQEMIADAERTGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYFGLETCMHLTCTDMGEEKVNDALARAYKAGCTNILALRGDPPREKEK
WVATEEKFQYARDLVAHIREKYGNHFGIGVAGYPEGCDDNKDEEQLLDHLKEKVDAGATF
IVTQMFYDADNFIRWMRKVRERGINVPILPGIMPIATYASFLRRANHMNCKIPDSWMTAL
EPIKNDDAAVREVGKTLVAELCRKIMAAGIVHLHFYTMNLAQAARMVLEELDWLPTTTRP
RKQALPWKQSLGLRRREEDVRPIFWRNRNKSYVSRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKKWGEPKCIKDIATLFVRYIEKDLQTLPWSEAPLTAEADSIREDLIK
LNQRGLLTVNSQPAVNGVKSSHPVYGWGPSNGYVYQKAYLELLVPPELFPEIVSRIHNHP
DLTYYAVTRTGALKTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAYRLGKDW
AHCYDANSPSRVLIDKIMDEWYLVNIVNNDFHQPRTIFELFEGLHVDNLDVHSTPVSNGV
HSESNGDAGHTNGSGSAAAA
>E2MVT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium amycolatum SK46|TrEMBL
MTMSSSMPLSPGRQVSIRQALSMPSAGSIPFSVEFMPPRDDAAEERLLRAAEAFHDLGAS
FASVTYGAGGSSRDRTLRIAQRVSKQPLTTLVHLTLVEHTVDELREILRSYLSAGLTNLL
VLRGDPPGDPLGPWVETEGGLHYASELIELIKAEPEFEKFEVGIASFPEGHYRSPDLDHD
TQYTLAKLRAGAEYSITQMFFDIEHYLRLRDRLVEADPVHGAKPIIPGLMPITSLRSVRR
QVELSGAQLPSDLEERLIKAADGDEQANKDEIRKIGIEFSTNMAERLIAEGVPGLHFMTM
NFARASQEVLHNLGMAPAWGTGQDMLRGGF
>I7KGN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus raffinolactis 4877|TrEMBL
MKITDIYREKNLQKKSVISLEVFPPKTDAGIETIYQTVAGLTHKPDYISVTYGAMGSLGR
ENKTLEIAEKIKKEYGIETMHHLTSINNNPEQITEILAEIKAKNVQNILALRGDLPKNTD
VTGCPDIYHYAHELITDIKKTGDFDIAAAIYPEGHVDSPLDVENIEHVKRKYDAGANFFI
SQLFFDNDKFLRLNDYVKNSGIEAPIAAGIMPVLQESQVARMLYFGASLPTRLIKIINKY
KDSPEDLQKAGMDYACKQIDDLLARGVDGVHIYTMNKPFVANTMMDHYL
>A0A7S6MIB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKSQKKFLPAFSFELFPPQTPEGVEKLRLTRQQLARFNPKFFSVTFGAGGSTRERTLETV
LEIQAEGHVVAPHLSCIGSTQENIRAILEKYYQAGIRHIVALRGDLPSGMAQAGEFRYAS
ELVAFIRQEYGASFHIDVAAYPEYHPQARSAQTDFENFKRKIETGASSAITQYFYNADAY
FHFVESCESAGLNIPVVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLESYGDDSESIQA
FGLDVVTELCERLLQAGAPGLHFYTLNSAKLTSTIWQRLSLQNQ
>A0A845R618|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colidextribacter sp. OB.20|TrEMBL
MKLCELFGKGRTVFTCEVFPPKRTAPVDSIYKTLDGMKDIRFDAISVTFGAGGSTVNQST
QEIACLIENQYHTPAMAHLTCVAAGREEVDRILDQLKAGGVENILALRGDANPDYPPKTD
FKYASELVAYIRERGDFGVSAACYPEGHLESPDLVSDVRRLKEKVDAGAQHLVSQLFFDN
GDFFRFLERARIAGINVPIEAGIMPVLSAKSIQRMVSLCGASMPAKLTRILARYGDHPDA
LREAGVAYAIDQISDLIAGGVDGIHLYTMNNPDVARQIAGSIDAIRKI
>A0A7G2TMG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger sp|TrEMBL
MKRPEISFEFFPPRNIEATFRLWDTVQALAPLKPNFVSVTYGAGGTTRELTREVVATLHK
HSGLRVAAHLTCVDATRAETLAIAEQFRDAGVKDIVALRGDPPKGASGFTPHPEGFGSSV
ELIEALRKTGDFNIRVGAYPDVHPEAANAAADVEWLKRKLDAGASEALTQFFFEAETFFR
FRDACAKAGIEKQIVPGILPIENWKGARRFAEACGTKVPAWVIEAFEAAERDGRQDLLAT
AICTELCTELLENDVDKLHFYTLNRPELTRDVCLALGIAPETTLENVA
>A0A2E5V9C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTNLSFEFFPPKNDSMKEKLWSCMKELSSFSPKFVSVTYGADGSTRDRTHDVVENITKKT
NLVCAPHLTCIGNDEKEISKIAIGYWDKGIRDIVALRGDLPKNFDININSNSFNYAFELV
ECLARLRKFNISVAAYPEVHPEAKNAKEDLDNLKRKIDAGASKAITQFFFDVDIFLRFRD
KCFDAGITASIIPGILPINNFDNMVNFSKKCGTTIPKELFDMFSEKKIDEKSKKSLAISY
CKRQIELLSNAGVEEFHFYTLNKSDLISKILKK
>A0A3B8RC49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MFTESEFLFTAETTPNLSTDLARSAGKIDPLVELADAINITDSPNCQTKLSSLLVAAEVK
RKGLDVILQLTGRDRNRIAIESELLGALSIDVNKVLCLTGDQPAPDGPKAVNEYNGTGLI
QLATHLSQGSISDGSAIDTPKPLYPGAADDLYQHQKNPEAITALMAKIALGARFVQTQYC
FDIDVIR
>A0A2E2YT26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTSKRAHISFEFFPPFTSKGQKSLLKVAKRLNTFKPEYFSVTYGAGGTTRERTYETVSSL
CQFGYTTVPHLSWGADTESEILELLDRYAQLEIGRVVALRGDLPSGLGNKQNIRYAKDLV
NLIQKNHPSWLVEVAAYPEVHPDSNNQNQDALYLKEKIDAGASGCITQYFYNTDSYFYFV
DLCRSLGITVPIIPGIMPITNQAKLEDFSKKAGAEIPRWLTKRLNDYEPESEDLLQFGIE
FVSRLCERLLAGGAPGFHFYTLNKAKSSESIAENIGFLENI
>A0A3D2KU93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
TQLVRFSNMCGAEIPKWILERLKLYENDLDSLTAFGTEVVSNLCQTLKDQGVDSFHFYSM
NRTEPSLSIAKNLL
>A0A4R2L643|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plasticicumulans lactativorans|TrEMBL
MNFELSCEFFPPNTDEGAEKLCEVRQALRALRPAFFSVTYGAGGSTRNRTFEAVIKMQEE
GGCDAAPHLTCVASTRDGVRAILELYRGHGIHRIVALRGDMPSGMLDPGEFSHANELVAF
IRAETGSHFHIEVAAYPEYHPQATNPAKDLEHFRRKVEAGADGAITQYFYNADAYFRFLD
DCARIGIGVPVVPGIMPITNFVQLARFSDACGAEIPRWVRRRLESFGDDRDAIRAFGLDV
VTALCERLLAGGAPGLHFYTMNQSAAVLAICDRLGLVH
>A0A1Z9GDB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium TMED143|TrEMBL
MTDISFEFFPPKSPEAEEKLWTAVGRLEPLAPDFVSVTYGAGGSTRDRTHACVRRLVDET
QLKPAAHLTCVAASRADIDSVIEAYATAGVGHIVALRGDMPDMGEFQPHEDGYSGSVELV
EAIAARGGFDITVSAYPEKHPESSSLQTDIDLLKAKADAGATRAITQFVFDTPAHLRFRD
AVAAAGITIPLIPGIMPTTNFAGARRMAAACGTHVPDWMSAMYAGLEEDPDTRKHIAASI
ATDQCRTLLDEGFEHLHFYTLNQADLTFAVCRILGLCDSQQESKPL
>A0A2D9SLC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MARSPDTVQLSFEFSAPRSQQATDNLLNTYQRLVKQAPDYVSVTYGAGGSSKDGTVQAVL
ALAAXGXQVAPHLSFGNDSKDSIAALLHQYKDAGIDRLVALRGDAPSGMTGTRGMXHASD
LVAFIRQETQQHFHIEVAAYPEVHPESTSVESDINYFKLKMDAGANSAITQYFYNADAYF
RFQDNCAAVGLSAXVVPGXMPITNLEGLVXFSNNCGAEIPXWVLKHLQRYADDQXALQAF
GEEVVTALCEKLLQGGAPGLHFYTLNRSXPSARICRNLGL
>A0A3M2BS92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MQSQKQYPKAFSFEFFPAKNPDGEAALLEVAQTLSQVEPCYFSVTYGAGGTTRDRTFGAV
QAIKTATGVDVSPHLTCIGSTREFLKELLEQYREMGIRHLVALRGDLPEGSDDPRVFNYA
NELIEFIRQETGDHFFIEVAAYPEFHPQAVSARADLENFRRKVEAGADAALTQYFFNPDA
YFRFVESCEKMGVDLPIVPGIMPITNYKQLARFSSFCGAEIPRWLARRLEDFGEDLASIR
ALGEDFITDMCQRLLEQGAPGLHFYSMNKVEPSLTIWKNLGLSPRRSERLGLK
>A0A3D2KW19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTSFEFFPPRTDKGKQTLAQVRQELSAINPEYFSVTFGAGGSTQDATLETVLDIQANDG
VSAAPHLSCIGSEKAKIIELLDQYKAADINRLVTLRGDIPSGVRDIGDFRYANELVEFIK
SEYNNHFHIEVAAYPEMHPQAKNIQTDLEHFANKIKAGADAAITQYFYNADAYFRFRDDA
QKLGIDVPITPGIMPITNHTQLVRFSNMCGAEIPKWILERLKLYENDLDSLTAF
>A0A1X3P4T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nesterenkonia sp. PF2B19|TrEMBL
MTPSVPSAGTLPQHALDSDDHTPHTSYLVQRTRRRSLISFEVFPPRPATAGRDPWRSIEL
LAEAGPDYFSVTHGHNQPEGANLEVIRHLLRSTPSPVMAHLISAGRSPAQVRRAVEQLLD
LGVRDVLALRGDPPGGAREWIHQPAGLNRAAEVVRLVREVEQERLDPPEGPGARPVSISV
AAYPPSGTDRDHEADLCALWEKQEAGADYAITQVFYDPEDYARLVDDARSQGIHLPVVAG
LAPLTSPKRLRRLEEISGVPVPQHLLDYLDVADPAERRRRGVAATLNLIDAVLELGCPGL
HLFTFNQHPAALAILDHLRIRDAARQQRVLPELP
>A0A1H9LGP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinokineospora terrae|TrEMBL
MLERLRGADPVFSVEFFPPRNDDEERLLWRTIRELEPLDPAYVSVTYGAGGSRRDRTIRT
TGRVATETTLLPVAHLTAVDHSIAELRNVIGWYASVGVRNILAIRGDPPGDVNGEWVPHP
LGLSYAEELVRLVRELGDFCVGVAASPYGHPRSVDLATDTDHLVRKLRAGADFAIAQLFF
DAEDFLRLRDRVAARGCDALLVPGVMPLTTVRTFTKAVELAGVPAPARVVSRLLRWEDDA
PSFRKAGIDLATELCADLLAESVPSLHFYTLNRSKATREVVSRLGLVRARV
>A0A359BCV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKRPTILLAILWIRINPDGRTLTKSSHKMKTFNAKVSLKGWSIEITPKESKTISCFSAFL
EKGTKVNVTSLPKTSVRDTLTAVEKLKRDGMNPIPHITARTTADEGDLARVVEKYADLEI
SEVLIIAGTKDQPAGRFSSSADLISSGVFEHFGIVNIGVAGHPEGSPDITEQQLQDALDQ
KNHLAVSRNLNIFLETQFCFDAQRIINWEKVIRDRGNMLPIRVGIAGPTKFLSLINFAIK
AGVGPSLKFLINERDKLTKLVNSYDPTELICSLAPQFSPEANTCFESVHFYAFGGFRKTA
VFAQELFK
>A0A3A4VWE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
IQRAGLSAAPHLSCIASSRAELRELLSAYKRHGIRHIVALRGDLPAGAGKPGELPHARDL
VEFIRAETGDYFHIEVAAYPEFHPEARDAAHDLHNFKRKVETGANSAITQYFYNADAYYR
FVESCEKMGVTLPIVPGIMPITHYAQLARFSDRCGAEIPRWLRKRLEAFGDDAASLRAFG
LDVVTELCRELLDAGAPGLHFYTMNQAGPAVAIWKNLNLDVKLTQGGHS
>A0A661EAA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPPMTQTGPVFSCEFFPPKTEDGINKLTATSKALADVKPRFFSVTFGAGGSTRDRTFETV
VNLQKESGIDTAPHLSCISSTRENIREMLTGYQDKNINHIVALRGDMPSGMVEAGEFRYA
NELVTFIREETGDHFHIEVAAYPEYHPQATSPDRDLANFKRKVDAGASSAITQYFYNPDA
YFRFIDRCNSVGIDIDIVPGIMPITNYYQLARFSDACGAEIPRWIRKRLESYGEDLESIR
TFGEDVAASLCTRLLEQGAPGLHFYTLNRAEPVLAIWGKLGLEASQHSQ
>A0A3D3DSD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MVTDTAADTLPDLKSGSNLEKVLAAGHFAVTGELGPPKHMDTSVVDRKIGLLKGVVDAAN
VTDNQTGIVRLSSIATGIYMAQHGLEPVIQMTCRDRNRLAMQSDLMGAYIHGIRNVLCLS
GDHQSFGNHPGAKNVQDIDSMQLIRMLQEMRDKNQFQCGDEIKGGGPKLFIGGAGSPFSE
PISFRPLRIAKKMAAGVDFIQTQMIFDMDIFRQFMRRLVDLGVTEKVHILAGIGPLKSSP
MARFLNENIPGIVIPEDLLKRMDGAVQSISEDNKEARRDAWRAEGQDICIEQIEELQQIE
GVSGVHIMAIEWEAAIRQIVERAGLLPRPIV
>A0A522M1B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MESQKKRARVFSFEFFPPKDTEARARLRDATAQLAQLKPKFFSVTFGAGGSTREGTYEAV
KEIQAAGHAAAPHISGIASTRAEIRELLSRYKALGIHHLVVLRGDRPKNGSDPTGDFRYA
NELVEFIRAETDSAFHIEVAAYPEFHPEASTAEADIDHFTRKVKAGANAAITQYFFNPDA
YYRFVDACEQRGLDLPIVPGIMPITNFKQLARFSDACGAEIPRWIRRRLEGYGDDLDAIR
AFGLDVTTELCRQLLDGGAPGLHFYTLNRAGPTCTIWERLGL
>A0A559PNP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gillisia sp. Hel_I_86|TrEMBL
MKITEHITAAKGKTLFSFEILPPLKGQNIQSIFDGIDPLMEFNPPFIDVTYHREEYVYIE
QPNGFLEKKVVRKRPGTVGICAAIQNKYGIDAVPHILCGGFTKEDTENFLIDLDFLGINN
VMALRGDAVKSETYFKPEPNGNCFASDLVSQIQEMNQGQYLDTPLEKNHTTDFCVGVAGY
PEKHMEAPSLDNDIERLKTKVAAGAEYVVTQMFYDNSKFFEFVAKCRKSGITVPIIPGLK
PLATKRQLTNIPHRFHVDLPEELIKAVNNCKTDLEVREVGVEWCTAQSKELISSGVDVLH
YYSMGKSTNIHKIASSVF
>A0A3C0C108|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKEISDATAKRIKEDLEKSYMEVIPVPGIEDKVDPLPSEMYLAVTCSPTKGVDETLDLSE
KLIGKGFKVTPHIASKCVSGEKHLETIIKKLDELGIESIFVPGGDRPEPMGDFQNALDLL
KALKKLGHNLKKIGMAAHPEGHPDVSDEVLMEALDEKKDLADFIVTQMCFDAEILNDWMT
EIHKKGIQLPVWVGLPGVIERGRLLKTSLRIGVGDSLRFLRKKSQVATELMKSSIYNPND
LLRDITEQNDINTSNLAGYHIYCFNQIETTEKWRTDIISSLN
>A0A2E1M362|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDSEXSPFSIEFYPPRNAEGESRLDAVHAXLAKLNPDYFSVTYGAGGSTKTGTSKLVMKY
QAAGSQVAPHLSFGGTDEQEVLELLQTYKEAGIKRIVALRGDIPSGSGAPMHYRYANELV
KFIRKXTGDYFHIEVACYPETHPEAKNXSDDVAFFKQKVDAGANSAITQYFYNVDAYFRF
VDYCDSQGINVPIVPGVMPITNFDNLKRFSAKCGAEIPLWLGKRLEDFGYDVTGLKQFGQ
DVVTELCYDLLQGGAPGLXFYSMNLSKSVSQIWSELGLQDRNT
>A0A2D8QV57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MWPSAVRHRTLSGSSSSCSKHRSSADSKSALRIERRNLSCHEISDGFAKPILSDYPVLVY
YPRTYSFLPVLLVQRFREALSQETFVLTAELPLSPKLNRHAIVSMAEKLSLSVTAIQIPD
HTNARPHISNLTASALLLQAGIDPIMHMNSRDRNRISLQSDLLSAQALGITSILLMRGMD
LPSDHRPRATSIFDVGAIDFITTASAIRDGEALSSARDEHVSPFQIGAIAQVFDPAPDWT
PEKLKAKTDAGANFIQLPLCMNLEILTRYMQKLISARLLWKASVMVTIAPFADREAAVKT
KASLPDSLIPQSIINQLEQSANPRQTGIDICAEILTAISMIPGISGANILVDEDVSAAAE
VVTAFQAAQPS
>A0A358ZE85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
PRWLAKSMSSYASDDKGLVDFGVEVVTKLCERLLELGAPGLHFYTLNRWGASSQLCRNLG
FLER
>A0A7Z0NYQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. SbOxS2|TrEMBL
MTAISFEFYPPKTDEQRTQLDRAAAKLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAQDALLDLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VQRLGVQVPITPGIMPISNFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGAEVV
AKLCQRLIEGGAPGLHFYTLNLAKPTVSVLTLLRG
>A0A1H7VUU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesobacillus persicus|TrEMBL
MSFLQRLKNEILIADGAIGTLLHSYGTDNCFEEFNLSRPDDIVRIHQAYIEAGADVIQTN
TYAANYLKLQRYGLEDQVKEINSLGVRHARKAASNKAFVLGTIGGNRGIRPNNVSLEEIK
RSFREQLYCLLLEGVDGILLETYYDKAELETVLAIARKETDLPLIAQVTLQEQGLLQDQT
RLNDAFKKLESLGADVVGLNCRLGPHHMISSLEEVELPQKAFLSAYPNAGLPSYTDGKFQ
FESSADYFRQSARRFREQGVRLLGGCCGTTPEHIRAFAAELKGLAPISEKTVVKYKDKIT
VQSPTINRAEPALHEIVKTRPSVIVELDPPRKLDTTKFFEGARALKKAGIDAVTLADNSL
ASPRVSNSALGHLVKEQIGLRPLVHLTCRDRNIIGLQSHLMGLHTLGLHDILAITGDPAK
VGDFPGASSVFDVASFELIELIKQFNNGLSFSGKDLGQKGAFSIAAALNPNVRSLEKAVA
RMEKKIKCGADYFITQPVYSEKLLLDVYEQTKHLDAPVYIGLMPLTGSRNAEFLHNEVPG
IKISQNILDTMAKLKDNPTQSKREGIAITKSLIETAAELFNGIYLITPFMNYEMTVELAE
YAREYSNRVSRRKQNV
>A0A7X2MTT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter agglomerans|TrEMBL
RLSSLKPKFVSVTYGANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDY
WNNGIRHIVALRGDLPPGSGKPEMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADL
INL
>A0A126P552|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp. PAMC 26628|TrEMBL
MKVTEHLAQAKGKTLFSFEVLPPKKGENIHTLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFTKEETENALIDLHFLGIDT
ILALRGDPIKSEGVFKPEPDGHAYACDLIGQVSDLNKGEYLDQEQDDAWATNFCIGTAGY
PEKHFEAPNYGADIRYLKHKVDRGADYIVTQMFFDNEQFFDFERRCRAAGITVPIIPGLK
PLTTKAQLSALPRNFFLNFPEPLVEAISQCRDNEAARIIGTEWCLNQSRELMAHGVPSLH
YYSMGKSENIRKVARELF
>A0A5E7Y5V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. EC-HK361|TrEMBL
MTLSVDQLAEARVALDAPLYADVAGDIDVSFEFFPPKTEKMEETLWRSIATLAPLAPRFV
SVTYGAGGSTRERTHATVARIARDTAIPAAAHLTCVEATREEIDSVAQEYWAAGVRHIVA
LRGDPPVQGARYAAHPGGYENAAALVAGLRRLHPFEISVAAYPECHPDSGDATVDLDNLK
RKIDAGAGRAITQFFFEPETFFRFRDAAAKAGIAAEIVPGIMPVSNFAAVQRMSAMCGTD
VPAWMGRLFEGLDDLPDARQLVAATLTAELCRKLYAGGVKQFHFYTLNRAELSYAICHLL
GLRARFATKVEAA
>A0A412UKP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF15-51|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAQMITSEFNTPSVAHLTCVGRSHADIAAKIDEYRSAGVENILALRGDLPAGAT
EDDKPASDYAYARELIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELANKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A2H0Q9Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionales bacterium CG11_big_fil_rev_8_21_14_0_20_38_13|TrEMBL
MKVIEHIERAKDPLFSYEIVPPPRGRTVQDVVEVVKKLAPFNPPWIDVTAHSAGAYYSEN
SDGSIERKVFKKRPGTIGICGIIQNRFKIDTVVHLLCHGFTKEETEDALIELGYLGVENV
LALRGDGLNYDKKITTGRSTNKYSSELVEQIVALREGQYTSDLSEAQPLNFCIGVAGYPE
KHFEAPNLAIDIQNLKKKVDAGADYITTQMFFNNDHYFHFVQECRKAGINVPIIPGLKII
KSLSQLRTIPRNFYINFPDDFVSEMMANPTHVKEIGLAHASKQVEGLLNYGVPSVHFYIM
NDADNVINVVKKFR
>A0A1W2C4K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. YR221|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINNLGRGKYLHDEDQICDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQRAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELITAVENAKNNEAVKQIGVEWAIAQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A4R4MZU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea longispora|TrEMBL
MALGRHSFFPERVPTVRDMLAGGGRSFSFEFFPPKTDEGERLLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERVARATTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVR
GDPPGDPAAEWVPHPEGVHYAEDLVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTDYFVR
KCRAGADYAITQMFFEADDYLRLRDRVAAKGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPRLAARFEAVKDDPAAVRRLGIEHGAELCQRLLDEGAPGIHFITFNRSSATREVFQRLS
GMRLSA
>A0A399G8F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermobifida halotolerans|TrEMBL
MLGSPTRPVSRPRRISDLLATGEPTFSFEFFPPKTPDGERMLWRAIRELESLRPSFVSVT
YGAGGGTRDRTVEVTERIATDTTLLPVAHMTAVNHSVRELRHLIGRFAGAGVCNMLALRG
DPPGDPLGEWVKHPEGLSYAEELVRLIRESGDFCVGVAAFPYKHPRSPDVDTDVEFFVRK
CRAGADYAITQMFFEPDDYLRLRDRVAARGCDVPIIPEIMPVTRYSTIARSEQLSGAPFP
ARLAEEFARVADDPEAVRALGVEHATRLCERLLAEGAPGIHFITFNRSTATREVYQRLVG
AHRPGVAAAAARP
>A0A143BXK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces qaidamensis|TrEMBL
MALGTASIRSDHARTVRDMLAAGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSLDWDTDVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLERIGSLTNAAF
PAALKERILTAQDDPAAVRSIGIEFATEFCAQLLAEGVPGLHFITLNNSTATLEIYENLG
LHRSPQA
>A0A6N7VJL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium sp. FSA-380-WT-2B|TrEMBL
MKIKELFKQKQPTISFEVFPPNKIYTLEKVYEVIDELSLLKPDFMSVTYGAGGSTRRNTV
DIASKIKNINNIEALAHLTCIGATKKEIDEILKDLNKNNIENIMALRGDIPQECENKIGE
FSHANDLIKYIKEYGDFSIGGAFYPEGHQETNDLLDLFNLKTKVDSGTDFLISQIFFENE
KFYEFKEKLGKLNIKTPLIAGVMPITNGKQIRRITSMCGCSIPEKLKKILDRYEDNPIAM
REAGIAYAMEQIIELISDDIAGIHIYTMNRVEASKKIMENIGNILRKRDENYGY
>A0A7K2W3G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID2888|TrEMBL
MALGTASTRTDRARTVRDILASGKTTYSFEFSAPKTAKGERNLWGALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVEDTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGSWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPERHPRSPDWDSDVAHFVD
KCRAGADYAITQMFFRPESYLRLRDRVAAAGCTTPVIPEIMPVTSARLLERLPQLSNAAI
PADLKERILGAKGDPAAVRSVGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSQRT
>A0A839VWC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. OGB3|TrEMBL
MTSGTPSVSFEFFPPKTEKMEQSLWQAIQRLAPLGPSFVSVTYGAGGSTRERTHNTVTRI
QKETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPETEGGVGGRYVPHPG
GYAYAADLVAGMRKVADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQFFFD
NDAYFRFLDRCAAAGITVPIVPGILPITNFARAVEFAGKCGAAMPKRFAETFEGLDADPE
TRQLVAATMAAEQCQALQAQGIRDFHFYTLNRSDLTVAICRMLGVKAKQPAVS
>A0A0A8XFM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDTIDKVLHFSGK
ARDIQDFEHFLEQAKAANIQNLLLLTGDKLKEHQNGRDGQPRSRYLESVNAVMTAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTQHAYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLKLEALEELWNSLWQVTSGKEFSPEIARFSR
QPTTKQMIKYRQLHVMHEAIFGSKIAKGVGRFIFKASFWENALVAKVLLKTEVLSKHSLV
GCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVEQT
DVLKEKLIPTVAIETRGTSSWKNWYLATEA
>A0A329KAI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. YN15|TrEMBL
MGEGQRLPDLREALLHGRLTGDGAMGTYLYQLGFPVGASYEEFNLEKPDIILDIHRRYVE
AGAQLVETNTYSANRDKLSKFGLEQDVAAINRAGVRLAREAAGDAAYVLGAIGSLAGGRK
RPAGKERVRQNVREQAEALLEEGVDGIILETYYLLEELEAALEAVRLVDGRVPVICQLAT
DGNGLTLDGAAYAAAFKRLLEGGADVAGFNCHSGPGGILRALDRLGADSSWTPGVPLSVY
PNAGLPGIVDGRYTYLATPEYFADMALKFAAAGARIIGGCCGTTPEHIAAIAKALAGYAP
APASGGQDKAKAERREKVTVAEPSAEAPASGGQPSIVELVRDSVTVIVELDSPRDLASAK
FMTGAAVLRDAGADAITMADNSLAQIRMSNLAMGYLVKDRLGMRPLLHVACRDRNLIGTQ
SHLMGLHALGIDHLLAITGDPAGVGDLPGASSVYDLNSFELIRMSKQLNEGIAFSGKPLK
QRASFVVGSAFDPNVKYIDKAVLRMEKKIEAGADYFMTQPVYDASMVERLYQATRHISAP
IFVGIMPLISGRNAEFLHNEVPGIRIPDAVRSQMAGLEGEEGRRMGVKLAKELVDVILGR
FNGIYLMTPMLFYEMTAELTRYAKERVFPLVPLSKMN
>A0A4R0F167|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4178|TrEMBL
MPLFTDSLQNQPFSIFLEYLPTKHAQPVPSSIGGYPVIMTIADRVRTDDDPEPLAIAQNY
AAEIPKILHFSGKGRDIADFNAFIRAAQEQGYSNVLLLTGDKLKHHQNGQEINFPRTRYL
ESVNAVMQCKKLAPEIKVGVALNPFKYAKAEHDAQYYKLDKKVRAGADYVVTQLGFDLDA
LKEAKQYLENQHLQVDLFACVMPLTAARAEFMVKQKVAGIVLTPHLLQLLKQEQGRDAVI
AEQNVYARCALQILICRYWGFAGVHLSACHKPEEQQKLEQALARFQDFSFDQCIQLWREL
HQLQSGDELKLKPDVLQKKVSTEQVLKYKSMQLMHDSMFDSKIARNLGSKFFNPKHWSGH
FANKLLIKSEYLSKHGVVGCESCGQCRLADTLYICPETCPKGLANGPCGGTTLDLCEFGD
RECIHSVKARLAQQVNQVGILKERLIDTVPIESRGTSSWVNWFKPK
>A0A8H9WHK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cycloclasticus sp|TrEMBL
MALESHQPISFEFFPPKTEEGREKLLAVSKKLGQLDPAYFSVTFGAGGSTQQGTINTVMD
IKKQGFSAAPHLSCVGSTKENIREILANYKTQGVDRIVALRGDIPSGTLDVGEFRYANEL
VGFIREETGDHFHIEVAAYPEIHPQAKNAQTDLANFKQKVEAGANGAITQYFFNFEAYIR
FVEDCDKMGVNVPIVPGIMPITNYSQLARFSDMCGAEIPRWIAKRLEGFADDRESIKAFG
LDVMSELCQSLLDYGSPGLHFYSMNQAEASLAICRNLGIDNA
>A0A4R6ZF69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas ventosae|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGKFAITSEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGANCHMSSAGVCSLLTRVGYATILQISCRDRNRIAMQGEILGGAAMGAC
NLLCLTGDGVQAGDHPQAKPVFDLDSISLLQVARNMRDEQRFESGRRIETPPRIFLGAAE
NPFVPPLDWRPLRLAKKVAAGAQFIQTQYCFDIERLRDFMLKVNDLGLLEGPDRVFILPG
IGPLASARSARWIRENVPGVHIPDAVIARLEGAKNQKEEGKRLCMDLLNEIREIPGVSGA
HIMAYRQEHSVAEIIEATGVLEGRVPWYPGRDDPKALNPESPEALSL
>A0A0A8XGB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLRIVHQELQLLNPDFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIRQHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A284R582|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armillaria ostoyae|TrEMBL
MKISQKIQQSTKEDKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTAEMVKTCQGIIGIETCMHLTCTNMPKEKVDIALREAKKSGCRNVLALRGDPPMGKED
WEAVEGGFVHGIDLVTHIRREYGDYFDVAVAGFPQHQLLPPEERDQELKYLKEKVDAGVS
FIFTQMFYDVEVFVAWVKAVRAAGITIPIVPGIAPIQTWNGFQRATSLAKTIIPQSFLEA
LEPYKNNDEKVREIGTKLVADMCRRILKEDIGIRGLHFYTMNLEKGTKMLLQELNLVPRC
LTPSRRKETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELDGYGVWIKQTKE
DAIKLWGEPKSLEDVTTLFARFCKGTLSALPWSDQAPAIETSVIANQLAQMNELGFFTIN
SQPAVDGVRSDDKVFGWGPSNGYVYQKAYLEFFVQPALLSLLLSHIERDSNITYYVINKR
GDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGQQWAKVYDAESPS
RKVISDLMDTCFLVNVVHNDFHDPDAIFKPFFRAGAEYKASLLNGNGNAN
>A0A1X3HZF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli M056|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A505H5L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. XM4083|TrEMBL
MVESTAVRLLEDFSLEMTGKDVDALREAAPAIPAGTRINVTYLGNEDLPMRVAAAQAVRE
LGFTPVPHISARRIASEQSLREFLAALRDAGASQHVFVVGGDPAVPEGPYPDSLTIIRSG
ILQDYGVREVSIAGYPEGHPDIEEATLWEHLSAKTAALSDQDLGQVVLSQFAFDADRVTA
WIAQVRAAGIDAEIRVGAPGPAGVKRLMGYARRFGVGASAGIVRKYGFSLTNLVGTAGPD
RLITDLAADLAGAGEAAAVKAHFYTFGGLAATAEWVRDFVKEA
>A0A0Q9R031|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Soil782|TrEMBL
MSPPSKSAHSVGPPASQPYPALSYELYPPRSTAAAETLWRTIRELEQTSPDYVSVTYGAS
GSNRDTAVELLSRLLSDSSLRPLAHLTCVGNSREYLLDLVDELITLGVRGILALRGDTPK
EPIVGAGDLPYASDLVKLVREAERRRTAHLCAGRLAVGVAAYATRHPESPSFGHDIEALL
AKQAAGADFAITQVFFFPDHYQRLVSAARRAGVDIPIIPGVMPLTSVRRLDRLAELAGIE
MDHQLRNRLAAATDDDARRRIGVQATVDLANAALDAGAPGIHLYTFNEHAAALDVLENLQ
LRRPPVPGGLSRTA
>A0A1I6FRK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robiginitalea myxolifaciens|TrEMBL
MKVTEHIAKSDGTLFSFEVIPPVKGKNIEELYRNIDPLMEFAPPFIDVTTSREEYVYIDR
DGLYDKKVTRMRPGTLGICAAIKHKYNVDTVPHVLCGGFTREETEYLLVDCQYLGIDNVM
ALRGDAMKGQSYFEPTQGGHTYASDLVEQIVKLNDGCYLHEVVETDAASKFCIGVAGYPE
KHLEAPSLKTDLKWLKHKVDLGADYIVTQMFFDNQRYFDFVAQAREMGITVPIIPGIKPI
AVKRHLQLLPQVFRTDLPEALIEAVVACKDNQQVREVGIEWSIAQSRELKEAGVPVLHYY
SMGKSDNIKAIAEAVF
>A0A8J1YQX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tremellales sp. Tagirdzhanova-0007|TrEMBL
MHLTDLIASRSVPFHTFEFFPPRTDAGFINLLDRVRRLAASPLPAPLAVSITWGAGGGTA
ERTMELAEQVTKLGLEVILHLTCTNMAKEKVDEALAKARALKIQNVLALRGDAPRTEEYA
IAPPTTPDFFKHADDLVRYIREEHDDWFCIGVAGYPTPHQDSESAETDLEWLKVKCDAGA
DFILTQLFYDVDGFEEWVGACRRRGISLPIIPGVMPIQNFASFRRLVNLTKCPVPDTILL
DLEPIKSDDAAVKRYGARLATHMVERLISTNLVPGVHFCTLNLEKSVRTILENLGWVSGS
NQIRSSPLPRHNQLIEDDTNVKNGVSIINGISSTAKQTNGLSISPSEASQLAQWGLTNNA
LPPAPKKGLGNSTTSANGPQGPSTEDSWDEYPNGRFTDVRSPAYGEIDGWGGGIKMSAAQ
ALRDWGTPTNHVELSALFTSYLQSDPTTPTTPFCDLPLSPESTTILPNLVALNSPRLQHW
TVGSQPAVDSASSEDPVHGWGPPGGYVFQKAFVEFFVPQDKMTTLEDRLSGRLDGQISMY
AANRMGGFKTNTLKDAVNAVTWGVFPGQEIVQSTIIEETSFLAWKQEEAFDIWTEWSLLY
PRQSPARRLLDGIASEWWLVSLIHHDYKDEGALWRFLLA
>A0A7Y2E5Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium|TrEMBL
MKVTEHLDRAKRPLISYEIIPPVRGGKVQRLLDVVEALLPYEPPFIDITSHAAQVVYEES
GEGIRRRVTRKRPGTLGVCALLQNKYNIDAVPHVLCRGFTREETEDFLIELNYLGIDNVL
AVQGDDSGYEKPLRDGRSANRYASDLVSQIRDMNAARYLSEDLADAEASDFCVGVGGYPE
KHFECPNIEEEIRVALRKVEAGADYIVTQMFFDNSYYHEYVARCREAGITIPIIPGLKIL
TSKAQVASLPRNFFLEIPSELTDEVAAADPKHVMEIGVNWARKQAEDLLNHNVPSLHFYI
MQRSKAIRSLLEQLDL
>A0A0B4R8F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus sp. PAMC 21323|TrEMBL
MGLLDELKTRILTADGAMGTLLYSYGIEYCNEELNLQRPEIVEKIHLDYINAGADIIQTN
TYGANALKLARYGLESQVAEINKAAIDIANRAATPGGQFVFGTIGGIRGIRKSDASLQEI
IAMVDQQANQLLEGDPHGLLLETYYDFEELAATVKHLKTITDTPLIAQVSMHDPGILQNG
MTLNDALHQLETLGADIVGVNCRLGPHHTIQAFEEVTLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGRAALLLREEGVRLIGGCCGTTPKHIEAVKKHLGQLKPIVHKIVTERKPIV
IREAEALAVTPLHEKAKTERTIIVELDTPRHLDVEKFLEGSVALKAAGVDALTMADNSLA
SPRISNMAMGSILKHTEDIRALAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKKLNEGISFSGKSLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIDSGADYFISQPVYTKEKIIEIYEATKHIETPIFIGVMPLTSIRSAEFLHNEVPGI
KLSDDALERMRACGDDKDLATAEGIQIAKELIDTAAKLFHGIYLITPFVRYDMTVELIHY
IRQLDQQKESDHSHVQASY
>A0A538SYI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium|TrEMBL
MSHPFLRRLEKGVVLADGAMGTLLYDRGITFDRSFDLLNLQEPALVQSIHRDYIRAGAEL
IETNTFGASRIRLAAHGESTDARRVNRAGAQLARNAREEVGEAVFVAGAIGPLGKPVAPL
GTITREEALEVYVEQVEGLVEGGVDLLIIETQTDLEEMKLAIQAVRKVTDLPLIAEMTFT
EDERTLYGAYPEDVVRATQNLGVNVLGANCSVGPQKLLEIVQRLRRRTELPISVMPNAGL
PRFVSGRFLYLASPDYFADYAVRFQAAGANIVGGCCGTTPAHIRRMRDALARPGAKAAEE
IAADRAAAPPPLPTVHPEELPSADPASRSLLARKLANKEFVVSVEVDPPRGARPKKMIEG
AQFLKASGVDVINVADSPMARVRMSSLALASMISQQVGVETILHFTCRDRNLMGIQSDLM
GAHALGIRNILALTGDPPRAGDYPNTTAVFDVDSVGLIRVLKQLNAGSDLAGNSIGEPTR
FLIGCAVNPASEDLETELERFQKKIEAGAEFTMTQPLYELEPLVRFLDAVGKKRVPVLLG
LLPLQSHRHAEFLHNEVPGINIPEQAREAMRAAGDKGIEVGVEMCRALLLKAKDMVEGAY
LMPSFGRYEVVARVAEVVRSAPKGAPRAPTPA
>A0A7K4X4C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Regulus satrapa|TrEMBL
MVNETQHPCSASSSSRSDGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDVCVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRSYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDELEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYEQRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A144PB52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter alimentarius|TrEMBL
MSKPAFSFEFFPAKTDQGREKLLSTFDELNTLSPTYFSVTYGAGGSTRSRTLDIVQALST
RGDTDIAPHMSCIGDDKSEIAELLEHYKSLGINRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFRIEVAAYPEMHPQARSFEFDVDNLVNKFQAGANAAITQFFYNADSYLYLR
DTLEKRGINTIDQPLVAGIMPITNSSNLIRFADSCGADIPRYVRKQLFDYGDDSKAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVEALGLTT
>A0A0H3PZ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O157:H7 (strain EC869)|TrEMBL
MNFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4P6GVQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylibium sp. Pch-M|TrEMBL
MSDTPSLKLPVPVSFEFFPPNTEAGSEKLKTVVRELGSAAPEFFSVTYGAGGSTRDRTLS
TVRDIAALGFEAAPHLSCVGSTRAGIAEILGTYRAQNIRRLVALRGDLPSGTATAGEFRY
ANELIAFVRETQGTDLRIEVAAYPEYHPQQRYARRDLQHFANKMKAGADAAITQFFYNPD
AYFHFLDEVRALGVDAPIVPGIMPFHNYARIAQFAMRDGIEIPRWVALKMEGYMDDAASI
RAFGIEVVSRLCERLIAGGAPAIHFYTLNQSALTLEVCRRLASARG
>A0A1A6FLG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylosinus sp. 3S-1|TrEMBL
MADARTSWPPGHFDISYEFFPPKTPEMEIQLWDSIARLAPLKPKFVSVTYGAGGSTRERT
HNIVARLVAETDILPAAHLTCVSASRAEIDEIVRGYWNAGVRHIVALRGDPPTGVGTKFE
PHPIGYQSSTELVRGIREIGDFEISVSTYPEGHPESRSIDDDIDALASKIDAGATRAITQ
FFFENDVYFRFLDKARKRGIKIPIVPGIMPVQNFKQTANFARKAGASVPGWLADRFEGLD
DDPVTRRLIAAAVAAEQVLGLAENGVREFHFYTNNRADLVFAICHLLGVRPVTEKAAA
>A0A4D7YAY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MIIKRIMHKLLDISASSIIPASIEASPAQVLGPASLAGLFPQGVRVYLTDTGAASQVRLV
DAARHLRDLGYEPVPHLAARRIPSRVEFEEQVKRLAGEAGVSDVLVVGGGVDRPAGPFAS
SMDMLSSGIFDRYGMKQIAIAGHPEGSPDFSEETAVAALRLKRDFAQRSDATMRIVTQFG
FDAARFIAWAEGLVASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESVVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVNRGSWQTGGADRSAS
PDSVAV
>A0A1H2HYQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis keratiniphila|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTPRTLHTSIKLSGAPAPRRLLDRLEPLA
DDPKAFRAAGIDAVTELGERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A1H9XWP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentzea flaviverrucosa|TrEMBL
MTSVVERLRGESPKFSVEFLPPRDAEDEKVLWKAVRELEGLDPAFVSITYGAGGSRRDRT
IRATGRIAQETTLLPVAHLTAVEHSVAELRNVIGWYAAIGVRNILALRGDPPGDPMGEWV
AHPEGLNYADELVRLVRELGDFCVGVAAFPYGHPRSGDLDTDLKFLLRKLDAGADYAVAQ
LFHAPEPFLRMRDRVAAAGCSAAILPGIMPMLSPRGLAKIVELSGADLPLDVSRRLEPYL
DDAVGFRAAGIDIATEMCQRLLDEGVPALHFYTMNRSKATKEVLGRLGLVTRA
>A0A374G8C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM28-13|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A1L9SHS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicilliopsis zonata CBS 506.65|TrEMBL
MHIRDKLAEQDAAQRPGISFEFFPPKTAQGVQNLYDRMDRMHALGPAFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKIDAALQAAYKAGCTNILALRGDPPREKEA
WEATTGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
VITQMFYDVDNFLAWVRKCRDRGINVPIIPGIMPIQTYASFIRRSNWTKVNVPPEWLEAL
EPVKNDDAAVREIGKTLIADMCRRLLKSGLINHLHFYTMNLAQATNLVLQELKLIPSEET
PLQRPLPWRPSLALNRRTEDVRPVFWRNRQSSYIARTQTWDEYPNGRWTDSRSPAFGELD
AYGIGLKGTNELNVKLWGQPRSIHELSDIFVRFIQGTLDRLPWSDAPITAEADAIKNDLI
DLNRRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPADLVDELIARMDRN
DDLTYHCIRRDGELRTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAFRLGEDW
AKCHEPSTPTRKLIQGIMDDWYLVNIVNNDFHKTHDLFDLFKDLTVKDLDRAIPSEVANG
TEA
>A0A1H0NPN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium sp. YR620|TrEMBL
MSFFRQSRRPDIGHNIRVSFEFFPPKTEVMEERLWETVTRLAPLNPEFVSVTYGAGGSTR
ERTARTINRILTETDVNAAAHLTCVDATKEEVDTVVREFAAMGVKRFVALRGDPASGVGS
HYKPTPGGYENGADLVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVEKVRRAGIYIPILPGILPIHNFTQVTNFCSKAGTHIPNWLAERFE
GLENDPQTHQLVASAVAAEQVLDLVERGAQDFHFYTMNRADLAFAICHLIGIRPGSNVVE
ANLAGAAA
>A0A2T7WBP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MTKTEIDRNPSSDFKLSFEFFPPKSPDMDVQLWETVEDLSRWNPDFVSVTYGAGGTTKAP
TLEAVRRMISVAGLSTASHLTCVDASKRETHEVVEELRNVGVRHFVALRGDPATGIGTAY
KPHPEGYENAAALVRGLKELGDFEISVSSYPEKHPESESNSVDIEMLKLKADNGATRALT
QFFFDNDIFERYMERVTKAGIKIPVVPGIMPIQNLTQLKRFAGRCGTSIPAFLDERFAGY
DDDPVGRAKVAADVAAEQIFDLQRRGVNEFHLYTMNRAPLVNAVLENVGFRPARKSAA
>A0A3D1NPH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp|TrEMBL
MNITDLIQGAVASRTTRFAFELLPPLKGDGTRSVFGAIDPLMDFNPAYINVTFHREALKE
DIRPDGSREWHIMRRRPGTVGISAAIRRKYDVEVVPHLICGGWSKYDIEDSLIDMDFLGL
HNVLALRGDKRQNEPRFVPYAQGHAHAADLVRQIQAMNRGEFIDGEVEECHHSKFSVGVA
GYPEKHFEAANPQSDLQYLKEKVDAGADYIVTQMFFDNSKYFDFVERCRKAGITVPIIPG
IKPISTPKHLEILPRTFSVSLPEELVKAVRACGEDTQAAREVGIEWAIHQAKELKAAGVP
IIHFYTMGRTDNIRKIARNVF
>A0A1B9V1P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MIRKRTKFKLHDISTSPAIAASIEASPAQVLGPASLAGIFPQGVRVYLTDTGQASQDRLV
DAAKHLRDLGYTPVPHLAARRISSGVEFEEQVKRLAGEAGVSDVLVVGGGVATPAGPFAS
SMDMLSTGIFDRCGINQIAIAGHPEGSPDFSEETATAALKLKYDFAERSDAAMRIVTQFG
FDPARFIAWAEGLAASGIDLPVHIGVSGPARITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESVVGPIERHWQANPAGPIRQIHVFPFGGLQNSADWLAGRGSWQIGDADFSAK
RGTVAI
>A0A6J4VAB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Thermomicrobiales bacterium|TrEMBL
GLTAPETVREIFEEQIAALLEGGVDLLVLETMGSVAEARQAILAAQAVGDLPIVALMTFA
EDGRTIGGETPERVVAELLPLGPAAIGANCSVGPARTLAVLRRLVAAVDAAAVADPPALA
VMPNAGWPTHIGGRVIYQASPDYFAGFAREALETGATIVGGCCGTTPAHVAALRGAMDAG
IAPAERHGARITISAGDGIDSAGNSLAIGAEPTDEPTEVARALGRSFLVSVEIDPPKGFN
PAKALAGAQLLKDAGVHAINVADSPMARVRMSAMTLSYLIQHQVGIETIVHFTTRDRSLM
GLQSELLGAHAVGVRNILALTGDPPSLGDYPDSSAVYDVDSVGLIRVLRRLNEGVDSAGA
SIGRGASFTIACAVDPTKADLAEEARRLRSKLEAGAHFVMTQPIFDLAVWHQFLDAYETE
WGTKDLGLPVMLGILPLQSTKHAEFLHNEVPGITLTDEARARMREAGSDGRQEGVRMAQA
LLADAVPHVQGVYLMPSFGRYEVAAEVLTAIPTGVRA
>A0A6L5WH21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter portucalensis|TrEMBL
MLCEKLKEGSVLLYGITPPKIGTSIDKTYEISSKLKNRIPSDLIDGFIIYDLQDESLRNS
DERIFEFFDTIKPEIYHEKFLNDYEAVIYKVVNKFSKDEFLNFINKNKNPVVFVGSSSSK
DSVKFSLKDAYKIKNSLNPNTLMGGICIPERHNLKNDEHFRVAKKSIFGCKFFITQAVYD
LESAKKFIDDYAKMSIEKRQIIFTLTPCGSSKMLNFMKWLGIYVGKEIEKTLLNSQNMLE
KSISLSLDMFKFLNTYSKNKGISIGVNVESISKTKVEIEASISLLKDIRKILK
>A0A6N7HVL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MTIRNEQLRQYLADARFEVLPLRGVLERAEQLPAGSTVTVTSSPTKGPDATLEVASDLRA
LGFQVVPHLAARLIADRHQLVEVLDRMADAGLSEAFVIAGDSTEPAGEFPDALALLRAMD
ELGRRPSRIGITGYPERHAFISDAAMIDAMADKSAYADYIVSQICFDAYTIASWTKAVRA
RGIELPIHIGVPGVVDATKLLRISLKIGLGDSMRFLRKQHGVVGKLLSRYTPEGLFDELA
PYLIDPAYGLAGWHFFTFNEIARTQRFRHEMSTRLEEVSA
>A0A1H1MZV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas oryzae|TrEMBL
MSQLKKALHDKTFVCVMEFVPKSSGESFASIEALMARAHLCGWPMTVAIADRVGSPVEMS
PLDAFASFKRPLPALLHFAGKDRERRHLLAQLQQMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQMVRQARPDWLLGAAMHPFKYREEEGGAQYFKAEKKLAAGADFLSLQLGY
DACKHQEAMHWMSRQPAPRPLLACVMALTLSRARIFRQVAGIVVTPSMLGLLEAEAAVSR
AHAQARSLDRLALQIIGLRLMGYAGIHLSGIHGLEQLLTLEQAINDWQARIHSLEEWAPA
WDACWRMPGGPAVTFHPPEANWRLGEASVSASSREMLRYQLLSGVHALLFDRRRWLSQAF
GWTLQRPVWSTPAGARLLHRLERGVKRPLVGCDTCGRCRLQDTLYICPETCPKGLANGPC
GGTSLNRCEFGDRECIHSVKYRTAQAVRQTAVLKDRLIPCVEEGTRHQSSWPAWFESSR
>A0A318TKH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ureibacillus chungkukjangi|TrEMBL
MGLLKALKSKVLTADGAMGTLLYAYGLDNCHEEMNIVRPDLIEKIHLEYITAGADVIQTN
TYGANSIKLARYGLEDKVSEINKAAVSIAKKAVGNRNQFILGSIGAIRGVRKSDTTLDEI
LLAIKEQAMVLINEKVDGLLLETYYDFEELTETIKLLRYETSLPIIAQVSMHEPGILVNG
MNLNDALKELQDLGADIVGVNCRLGPHHTIQAFEGVELPEKAFLSAYPNASLLDIEDGRV
IYESEVDYFARAAVQLRNQGVRLIGGCCGTTPKHIEAAKKLLQNLEPIEVKEAIVQKEVF
IQEAEPSILEPLHEKVKRERSVIVELDTPRHLEIEAFVEGAKTLYNEGADIIMMADNSLA
SPRISNIAMGSILKLQHGIRTMPHITCRDRNLIGLQSHIMGLNALGLHDILTVTGDPTKV
GDFPGATSVYDVSSMELISLIKQLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKIEEIYEATKHLSAPIYIGIMPLTSFRSAEFLHHEVPGI
KLSEEVLERMKACDGDKEKETAEGIAIARELLDAAAKHFNGIYLITPFLRYDVTIKLMQY
IKQLDEQNKGVKANV
>A0A1F4CZX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_62_13|TrEMBL
MQSQRKFPRTFSFEFFPPKTPAGKEKLRETWKQLGQLKPKFFSCTYGAGGSTREGTLETV
LEIRAAGHEAAPHISCVASSRADLKAQLERYRAHGIRHTVALRGDLPSGLAALGELRYAN
ELVAFIRETTGDWFWIEVACYPEYHPETRSAADEIRNFKRKIDAGANAAITQYFYSAAAY
FRFLDECEAAGIDVPIVPGIMPIGNFSQLARFSDACGAEIPRWLRFRLESFGDDTASIRA
FGLDVVTALCDELLSNGAPGLHFYTLNQAGLTTTIWQRLGL
>A0A2H6LAA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa NIES-87|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>A0A0D2GAF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dethiosulfatarculus sandiegensis|TrEMBL
MKSGSNLEKVLAAGHFAVTGELGPPRGNNAEEVLHKAEHLRGVVDSVNITDNQTAVVRMS
SVGACRILLDAGMEPNLQMVCRDRNRIALMSDLLGATALGIKNVLCLSGDHQRFGDHPEA
KNVFDLDSMQLLDTFRRMRDDKVFLNDKELDGAPEIFIGAAANPFADPFSFRVPRLAKKI
AAGADFIQTQCIYNLDKFREYMKRAVDRGLHEKCYIMAGLTPLKSVGMAKYMSKFVPGMD
VPQEMVKRLQEAGKKNQAQEGIKICIEAIQEVREIPGVAGVHVMAIEWEHRAKEIVEGAG
LLPRPQV
>A0A1H7NI67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea pusilla|TrEMBL
MALGRPSVLPDRVPTIRELLASGGRSFSFEFFPPKTDEGERQLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERLAHDTTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVR
GDPPGDVTGEWVQHPEGVLYAEELVRLIRQSGDFCVGVAAFPYKHPRSPSIESDTEYFVR
KCRAGADFAITQMFFRADDYLRLRDRVEAQGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PAEVAARFEAVADDPAAVRALGIEHGAELCQRLLDEGAPGIHFITFNRSSASREVFQRLD
VRQPA
>A0A3R7VDH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Puniceispirillum sp. TMED245|TrEMBL
MATSIETIQTAASNWSIEVTPTGATKIESFSDCLDAGTTVNVTFLPGTDPADTIAVCERL
HNDGMRPVPHLAARSLRDADQLEELLSAYTSRCGVEEVLCIGGGVDNPVGAFDATMQVLQ
TGLIQKHGIRHIGVAGHPEGSPDISDDEIAEALGAKNELAKAEGLELYIETQFCFEADIV
LDWERRVRAAGNALPIRIGIPGPATIKTLFRFAQISGIGPSMRFISKQAKNVAKLMTLQS
PHLLLTGLAEGMAADEECLIRHFHFYPFGGFARTATFAGAIADGNIKMLPKGGFEVIDG
>A0A432UQ55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermovibrio sp|TrEMBL
MTFREKVESGKFVITAEVAPPRGTDFKPIIDGIEPLRGKVDAFNVTDCQRSMVRMGALPM
AKLLLDFKLEPVLQLTCRDRNRIALQSDLLGAYALGIENVCLMTGDFTTLGDQPDSKPVF
DVDSVQLIEIVERLNLGELLNGKKLNGKTSFFIGGVFNPFAGPKRLQELKLEKKIRAGAK
FIQTQPIYDSNLAKEVSELIYSLGSTPIIGILPIKSLKMANFMKKLNPTSVPNSLIEGLE
RAKNPEEYGWKYAIDVARSCLEFAGGIHFMLVGKVHELANFIDYLKRDFNHKF
>A0A3R6K732|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium AF31-3BH|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGKDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKAAEI
>A0A291GC09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Celeribacter ethanolicus|TrEMBL
MTKAPKISFEFFPPKDIEACFSLFETLQVLGDMAPEFVSVTYGAGGTTRELTHDAVALLT
RKYGWNVAAHLTCVNATREETLAIAKSYKSVGVNEIVALRGDPPKGQGKFTPAEGGFATS
VELIAALKATGDFKIRVGAYPDPHPDAADETSDITWLKQKFEAGADSAITQFFFEPEDFF
RFRDRCARAGITGEIIPGILPITSWKGIQRFAASCGTPIPISYEAAFEHSQDHHKLSVDL
CTKLCEKLIAEGVEDLHFYTLNRPTLTKAVCANLGVA
>A0A142M6G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter aminovorans|TrEMBL
MTPPRPRQTDEHPDGIDLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSTSLLETVRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPYDFRPVHLGKKIAAGAQFVQSQYCFDVPMFRTFMNRVRDLGYDEKCY
ILVGVGPLASAKTAKWIRANVPGIHIPDTVIKRLEGAQDQKKEGKQLCIDIINEVKEIPG
VSGVHVMAYRQEEYVAEIVDESGVLKGRRPWKREARADDQRVAERLEHILHDDVTESQVD
MVKTAH
>A0A6M5Y9E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma taeanense|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPLKGDNLKSLLDNIEPLMEFKPPFVDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFTREETEDFLIDLHYLGID
NALVLRGDPAKPFSTFKAKENGYTYASELVEQVANMNRGIYLHEEDTALAPSNFCIGVAA
YPEKHFEAADHDIDFQYLKHKVDKGADYIVTQMFFDNQKYFDFVERCRQAGITVPIIPGL
KPLSTRKQLQILPKLFHLAMPDDLVRAVEACENDQQARQVGVEWCVQQCRELMAAGAPVL
HFYTMGKADNVMKIAREVF
>A0A837C1S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria mucosa|TrEMBL
MNHAREIAALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHSIVKRIKQETGLDAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANNVIT
QFFFDVESYLRFRDRCVMMGIDVEIVPGILPVTNFKQLTKMAQVTNVKIPSWLSKMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRPR
>A0A4W6CQF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lates calcarifer|TrEMBL
MVNQVQRGDGTCQSCKSDSSGASNSGGESSKESSRCSTPVLDSDRSDRLRDKMRRRMESG
DHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAT
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVISQLFFRADTF
LKFLDDCRQIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIQQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLKMWGEELMNEVSVFEVFTCYITAQPNRSGHKVMCLPWNDEPLASETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGRNLTNAPDLQPNAVTWGIFPGREIVQPTVVDPVSFMYWKVRQSLLLKCTGK
CSAGCLFLHVSDISPTPLLNLRYEPVK
>A0A1W2AGG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. RU36D|TrEMBL
MARNDNGTGGKSNLRISFEFFPPKSDEMESQLWETVTELANWNPDYVTMTYGAGGSTREP
TLSAVKRMVGEMKLSTAAHLTCVDASRNEVRAVVEEFRAAGVRRIVALRGDPTTGVGTSY
VPHPEGYQRTADLVRDLVAYGDLDVSVSAYPEMHPESPSIDVDIDTLKSKADAGAHRALT
QFFFDNDIFERYLDKVRAAGIAIPIVPGIMPIQNLTQLKRFARRCGASVPAFLDDRFEGL
DDKPEDRAQVAADIAAEQIADLQRRGIHEFHLYTMNRVPLIAGTLERLGLRPRAANPAEA
AA
>A0A1G0L7D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium RIFCSPLOWO2_02_FULL_71_11|TrEMBL
MVPVSAGPVIPPAGVEPVPLAARSAWGRRLAAGEFVTTVEIVPPRGTEPEKMLESVRMLK
AAGVHAVNVPDGPRAQSRMGALMTALLIEREVGLETVIHYCCRDRNLLSMLSDLLGAAAH
GLHNLLLITGDPPKMGPYPEATAVFDIDAIGLTNLVYRLNHGLDPGGNAIGKPTAFVIGV
GVNPAAVDLDRELKRFAWKVDAGAEYAITQPVFDPAQLERFLARVEGYRIPIVAGIWPLV
SLRNAEFLANEVPGVSVPPDVIERMRRVQELGKEAAVAEGVAIAREMLQRVRPMVQGVQV
SAPFGRVPVALEVFQGV
>A0A1S1U0E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. ORS 3428|TrEMBL
MTVRQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYDRAK
VFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFIQTQYCFDVPMFKTFMQKARDLGHTEKVFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>R5YC38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:197|TrEMBL
MKISELDNKRKSLSFEIFPPKKDSELKNIDATLEILCELEPDFISVTFGAGGSSNCNRTI
ELAKKIKRNYHVEPVVHLTCLHYNKAEIDEFAKILTAEGIQNVLALRGDRTPNLTEKEDF
AHASDLITYLKPKGDFCFLGACYPECHPESTNKIDEIHHLKEKVNAGAEILLSQLFFDNT
QFYRFVEDCRIADINVPIVPGIMPVINAAQIKRMITMCGASFPERFQRIIHKFEDNKAAL
FDAGMSYALSQIIDLLANDTDGIHLYTMNNPVVARKICEGIQNII
>R5EJR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Succinatimonas sp. CAG:777|TrEMBL
MGVNNILALRGDEREDLEKVDFEHAVDLISYIKGKYGDKVNIIAACYPEGHIEAHNIVDD
VKHLKEKVDAGASQLITQLFFNNDSFYRFKERCDLVGIKVPILAGIVPVANKKQIERIVT
LCGVELPAKFTKIMSKYEDNLEALRDAGIAYAIDQIVDLITQGIDGIHLYTMNNPYIATR
LHEAIKNLI
>Q83X56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rochei|TrEMBL
MTTFSFEFFPPKTAAGEQALWRAVRRIEPLAPDFVSVTYGAGGSSRERTIQLTQRMVTET
TLRPVAHLTAVGHSTAELRRIIGQYADAGVRDVLVLRGDPPGDPRGPWQPHPEGLTHACQ
LVELVRSLGQFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFDVEDYLRL
RDRVEAAGCTTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAARERPDDAYRIGV
EHATAMADRLLAEGAPGLHYITLNKSTAALDIHRNVLSRSRSLHAR
>A0A1J5NXD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MRVPVVPGIMPITSSTQLMRFSDSCGAEIPRWIRLRLQSFADDSASIKDFGLDVVTQLCE
QLRCGGAPGLHFYSMNQSAAVLEICHRLGV
>A0A7X7XC21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistaceae bacterium|TrEMBL
MKIKDIFEKKRLVFSFEIFPPKTTTPLERIYETLDELKGLQPDFISVTYGAGGSTRDRTP
QIAMDVKNKYGIESLAHLTCVEATREDTEKIVCFLLDNGVNNILALRGDPPEGARDNFVK
GDFEHAIDLVRFLREKYGETISIGGAAYPEGHIECDDPIKDLHFLKQKVNAGVDFLITQL
FFDNELFYRFMERAYIAGINVPISAGIMPVVSKNQIERIVTLCGASLPQKFVRILHRYAD
DPRALEEAGIAYATDQIVDLIAFGVKGIHLYTMNKAHVARRITSNISTLREAVPDPKGEK
VLS
>A0A7V6VL47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MPGRPTVSFELFPPRGNDLEGIWRRMMRMAEASPDYFTVTYGASGASREGSEQLIRRLKA
ETDVPVVAHLTCVASPRQEVRNRIERLMDEGISDFLALRGDPPVDAELQHIPDEIPTSAD
LVRLIRQIQSERGIPDVRIAVAAYPSGRHYGPGELAALAEKQDAGADYAITQVFYDAEAY
AELVAGAREGGVSFPILPGILPLTDRGRLQRLFGLTGVKVPATLDALLAIEDDAVRLRRG
VDATLALLDRVLAVGAPGVHLYTFNRDHPALEVLAHLRERGLANPAYLATRNA
>A0A8B5X260|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Competibacteraceae bacterium|TrEMBL
MHSQADWPKIFSCEFFPPNTDEGMHKLFAAREALMRLRPAFFSVTYGAGGSTRERTFEAI
QAIQAHSGVDAAPHLTCVASTRAGIRDILDRFRDQGIHRIVALRGDLPSGMREFGEFRYA
NELVEFIRAETGNHFHIEVAAYPEFHPQAANPERDLRNFKHKVEAGADSAITQYFYNPDA
YFRFIDDCEQLGLDLPIVPGIMPITNFTQLARFSDGCGAEIPRWIRRRLEGFGEDRDAIR
AFGLDVVTDLCRRLLDGGAPGLHFYTMNQAGPTLAIGERLGLTTA
>T1BM33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MPIIPGILPVTDFTQLGRISARCGARVPVWLTHLFEGLDNDPETGKLVGAQVTAELCQSL
RREGV
>A0A2U3HDV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NWU49|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFHPESYLRLRDRVDTAGCETPVIPEVMPVTSVKMLERLPKLSNAAF
PDALKDRILAAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQT
>A0A1W6DMC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulosimicrobium sp. TH-20|TrEMBL
MTSEASFAHRPGRPRPTVSFELMPPRRPDAAPKFWETARRLVATHPDFVSVTYGAAGTDR
ATARQVVGRLLQGTPVLPIAHLTCVGASREDVESVITDFLDEGVRSFLALRGDPPRDQPD
WQPAPDGVRSSTELVALLREVEASRCASDPAVALRGAARPLTIAVATFCDGNPAAGTTRT
QEVRRLWQKQQAGASFAITQLFYDASSYTDFVAEARAAGVTIPILAGLLPTTEPARLRRV
EELTGVRAPQHLLDALDALPDPEAQHAYGIAYSVDLAQRVLDAGTPGLHVYTFNKHRAAL
DLLEGVHLGGGSVGTGGGASAAAAPLVPDLASGPWVTGTSLPTTSAATHGAPV
>J1KSK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. F52|TrEMBL
MKVTEHIERAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKHEQSFTPKDGGNHYAVDLVKQIKDLNCGQYLHEVIDTDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAVQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A1B8ZE06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium artocarpi|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVKKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAITQCRELLDFGVPVL
HFYSMGKSDNIKKIAGELF
>A0A1E5SNJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivirga sp. 4D4|TrEMBL
MKVTEHIKNAKGKTLFSFEILPPQKGESVQSIFNAIDPLMEFKPPFIDVTYHREEYIYKK
RENGLLEKVSTRKRPGTVGICAAIINKYGVDAVPHIICGGFSKEETENALIDLDFLGIDN
VLVLRGDAIKSEGRFEADPNGHSYASDLLQQVLDLNDGAYLHEEVKRNKTDFCIGIAGYP
EKHFEAPSLKSDLKYLKMKVEMGAEYIVTQMFFDNQKYFDFVEKCRANDIHVPIIPGLKP
ITTLKQMNVLPSIFHVDLPDDLVDALEDCKDNTAAREVGVEWAIEQSRELKEAGVPCLHY
YTMSKSLVTKKIAEALF
>A0A1H8TQY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. NFACC39-1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRSLLSQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGEHFHIEVAAYPEMHPQARNFEDDLLNFVRKANAGANSAITQYFFNADSYFY
FVDRVRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A124P975|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia singularis|TrEMBL
MNPIELSFEFFPPKTAQGVDKLRTTCAQLATLAPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFVRKVKAGANAAITQYFYNADAYFRFVD
DASKLGADVPIVPGIMPITNFSQLVRFSEMCGAEVPRWIARRLESFGDDKESIRAFGTDV
VAGLCRRLVDAGVPGLHFYTLNGAAATKAVCERLGF
>A0A2P6G4I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MTAETLASAVRGFSIESVPQDADRIDDFRDHVPTGTRVFIAWPPKATPESIVKSARKLHE
QEMVPVPHIAARRVPSQEFLRAFVGDLVAQAHVREVLVIGGDPATPEGPYTDTGSLLRSG
VLNEFGIEKVGVAAHPEGHPVMSGAVSREVLADNLAAARDHGMSVEAVSQFVLDPQAIDS
WHAEVYSSLAQGAPLLIGIPGLVSGTRLLKIANACGIGESIGLLRKNGLRMAKTVIGNSS
TQTLVEGLAPLANRATDVGGFHFYTFGNFEQTAAWACEAASTPAAAAG
>A0A352AQ21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium UBA9273|TrEMBL
MTNPTQNSFRAAVQSGEFLITAEVAPPKGGDPAHMLKMAQTLKGRVHAVNITDGSRAVLR
MCSIAASALLLQYGIEPICQIACRDRNRIALQADLMGAYALGIRNILALTGDPVKAGDHP
DAKSVFDVESVRLLQLINKLNSGSDCNDKPLTDGVTDLFPGAAVDPQLKSWSGLQRRFER
KLEAGAEFFQSQLISDFERLEMFMEKIAAGTNKPVLAGIFLLKSAKNAEFINKYVPGVNI
PQGIIDRLAIAEDPLKEGMKIAAEQVQLAKQLCQGVHMMAVKREDLIPQILDLAGIVPIQ
AVNS
>A0A1F9M811|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYD12_FULL_55_16|TrEMBL
MKSGSRLERILTSGEFAVTGELGPPKNGNAELVREKARLLKGSVDAVNITDCQTAIVRMS
SISAGLLTLAEGVEPVIQMTCRDRNRIGMQSDILGAAALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDAIQLLGMVKDMRDEKKFQCGEAIKSHEPRLFLGAAANPFAAPSEQFRAARLAK
KVANGADFVQTQIIYNVERFARFMQAVRDLGLHKKVHILAGVTPPKSVGMARYMKSSVPG
MDVTDEVIKRMQGAKDKEDEGINICVDIIRQVREIEGVAGVHIMAIEWESAVPEIVSRAG
LATRPLFADEPVALAAEAPTVIEVRSTVTKDSDAILAAAKVEAEKIIAAARLEAAQFRAS
ATTGGSGAGAVDQVKTEIEEAGEDAMNEKERQMALESVRLGLDALKKAYGLSDDQFDALV
KFAGAEAILKREPVLAAPVSAAPVPVAPVAPVAPAPVPDESIVRKAAEAAAEEEAKKAEA
VKKAAADKAAAEARQAEAAKMAVEAAAAEETKKAEAAKKAVEAKAAAEAKKAVAPEPEKA
APAVSSPSAATVGAAALALEKTPLSERAVKVPEASYKQAYTGAIRQTVLGNEASGIKVGG
AGTLPFHLFEGAMPNKPMIAFDVLDVKPDEWPDSLARHYQDVYDNPLAWAQKCVKEYGAD
AICISMVSTDPNGLNRPAGEAAKAAAEVVKNIEVPVIVWGCGNGEKDTETLREITSLIGD
KKVCLAPLSDSNYRAIGATAMAFQYPMVAASPIDVNLAKQLNILLENLGVSLDSVLIDPS
IGALGYGIEYTYSVMERIRLAALTQKDEKLQVPFICNLGREVWKAKECRLPTDEMIGDQE
TRGILMEAITASCMLMAGGELMIMRHPRAVALTKSLINGLMD
>A0A832L5Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp|TrEMBL
MLFNFREKLNSSKFLVTAEVSPPKGTRYSVPLGDTRQLKGIVDAINVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDFPSCGDHPGSKP
VYDLDSVQLLQLVRKLDSGINFAGNRLDGGTSFCAGAVSGIDPEKPLQLIKLEKKVKCGA
DFIQTQAVYDVGMFEEFMEAITHLEVPVIAGLIPLRSLGMAEFMNKNISGIRVPEEIMFR
VKDAPDPIEEGLSIASETIKELMKLSRGVHIMPVGSHENTPRLLSMAGISRK
>A0A5A7PN54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Striga asiatica|TrEMBL
SLLYRSPVSSSQIHPAGQPHATSHHRTSAPATVARPHQPPYSSPPTQSPTQSIDTRSRLL
PSPPPTHRRLDIPLPPPTLIGLNLLETNAVGCRSEMKVIEKIQEAAAANDGRVVFSFEFF
PPKTEDGVDNLFERMERMVAHNPTFCDITWGAGGSTADLTLEIANRMQNMVCVETMMHLT
CTNMPVENIDQALTTIKSNGIQNVLALRGDPPRGQDKFVQVEGGFACALDLVKHIRAEYG
DYFGITVAGYPEAHPDVIQDGVAPPEAYQNDLAYLKRKVDAGADLIVTQLFFDTDIFLKF
VNDCRQIGITCPIVPGILPIKDYQGFLRMTGLCKTKIPPEIMAALEPIKDNGEAVRAYGI
HLGTEMCKKIIANGIRTLHLYTLNTEKSALAILMREVIGLNLLETNAVGCRSEMKVIDKI
QEAAATNDGRVVFSFEFFPPKTEDGVDNLFERMERMVAHNPTFCDITWGAGGSTADLTLE
IANRMQNMVCVETMMHLTCTNMPVEKIDHALTTIKSNGIQNVLALRGDPPHGQDKFVQVE
GGFACALDLVKHIRAQYGDYFGITVAGYPEAHPDVIQDGVAPPEAYQSDLAYLKRKVDAG
ADLIVTQLFYDTDIFLKFVNDCRQIGITCPIIPPEIMAALEPIKDNEEAVRAYGIHLGTE
MCKKIIASGIRTLHLYTLNMEKSALAILMNLGLIEESKISRSLPWRRPANVFRVKEDVRP
IFWANRPKSYISRTVGWDQYPQGQSIFYRVVSAVFPGYFFDVGDFDVLISLLLLRFMRPR
ARDKKLREEWAVPLNNVEDIYENFMKFCLGKLKSSPWSDLDGLQPETKIINELLGSINLK
GFLSINSQPAVNGAQSDSPSVGWGGPGGYVYQKAYVEFFCSLEKLNALVEKCKNFPYLTY
MAVNKQGSWISNLNKTDVNAVTWGVFPAKEIIQPTVVDPESFLVWKDEAFEIWSRGWAKL
YPETDPSRKLLEQVESSYYLVSLVDNDYIHGDLFAVFKDI
>A0A1C5MXN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Eubacterium sp|TrEMBL
MNIREYLENHKLLTDGAMGTYFDSIEKENYICSEEANITNPALVREIHRSYVKNGAQLLR
SNTFLANEGTFLSLTQAKAEAFENITLKQLIIAGYQLAKETAQEVYQEEYPIFAAADIGP
ILEERDSEEADILQQYYEICDSFLEAGADIFVLETFPDTQYVLKMAEYIRKSCPEAFIIG
QFSLTPTGYSRTGFHYKTILQEATQSGLLDGAGLNCGVGAAHMKKFLKSYIEEFGVPEDM
VLTSLPNCGYPQIVRGHAVYSDSVPYFGEKLGEISELGVQVLGGCCGTTPEYIGEIYKTV
FQAKKTEGAVKIPTKIVWGDVTKRVQKRKEAAVHITQAGEQKEAIKEKQVTNTFRQKLEM
GELVCAVELDPPFDTDDTKLLNGAKALLSTKADIITIADSPLARSRADASLMAAKIKMTT
GMDVMPHLSCRDKNRIAIRSGLLGSYASGIRNYLFVTGDPVAREDREFTKSVFDFNSIRL
MKFAQSMNQEVFKDDTIFYGGALNQNGASPENIAGRMLKKMEAGCRYFLTQPVYDKEGIE
RLTFLKERTGAKILIGIMPLVSRRNALFIKNEMPGIHVPDEVVAKYKEGASREEFEEAAI
EISKQIIEMGKGIGAGFYFMTPFNRVSLVKSILEYV
>A0A3M3BLM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae|TrEMBL
MEVSSPMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLN
TVLQLENEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGEL
RHANDLVAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFN
ADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQ
SIQAFGEDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A3M2T073|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus sp. HF37|TrEMBL
MHIKEKLAQQEAAGKPGISFEFFPPKTAQGVQNLYDRMDRMHSLGPAFVDVTWGAGGRLS
DLTCEMVNIAQSVYGLETCMHLTCTDMPREKVDDALQAAFKAGCTNILALRGDPPREKES
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNQDVDLLVDHLKEKTDAGASF
VITQMFYDTDNFATWVKKCRDKGITVPLIPGIMPIQTYAAFIRRSNWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKTLIADMCRRLFAIGINHLHFYTMNLAQATRLVLEDLKLTPSEDMP
LPRPLPWRPSLGLNRRGEDVRPIFWRNRNSSYIARTQTWDEYPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNVSLWGEPKSPRDLTGVFVRFLEGELERLPWSDAPITAEAKAIKPNLID
LNQRGFFSINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELFVPSYLVDELIARIEKNE
DLTYHAVNKSGELKTNTRDSPNALTWGIFAGREVIQPTIVETISFLAWKDEAYSLGEEWA
KCHDAPTPSRKLIQGLMDDWYLVNIVNNDFHNTYDLFELFKGLTVKDLGVEVPADSAALK
PELNGTSKQNGDAKEPNGTSAEIASKN
>J2L4W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. CF313|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAARQQLYVRKPQFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGMGGEFLYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFATKVKAGADSAITQYFFSPEAYFRFVDD
VRKLGLDTPIVPGVMPITSSTQLMRFSDACGAEIPRWVRLRLQGFGDDTASIKAFGLDVV
TDLCARLQEGGAPALHFYTMNQSAATLAVLERLD
>A0A2U2J8P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter aquimarinus|TrEMBL
MKITDHIKNANGKTLFSFEIIPPKKGNNIQDLYNNIDPLMEFKPPFIDVTTSREEYVYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYVLVDCHYLGIDN
VMALRGDAMSHQKYFIPNEGGNHYATDLVKQIQDLNCGKYLHDVIESTNKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNNKYFAFVDAAKKAGINVPIIPGIK
PIAVKRHLQLLPQVFRIDLPETLISEVEKCKTNKEVRQVGIEFAIQQSKELLAAGVPVLH
YYSMGKSDNIQAIASELF
>A0A2N6QD95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oligella urethralis|TrEMBL
MNRIETEGSRFFSLEYFPPREQHARERLVETTKQLLEIDPDYISVTYGAGGSTREGTEDT
VQMVSNLGCEAVPHLACVGSQPEAIREILDSYQAKGIRRIVALRGDMPSGMGLADSPLRN
AVDLVRLIREHSGDWFSIKVAAYPEMHPQAESFDEDLDHFVAKVNAGANMAITQYFYNAD
AYWDFVDRAQAKGVTIPIVAGIMPITNYSKLARFSKMCGAEIPRWIAKRLESYGDDVQSI
RDFGHEVVSRLCDDLRRGGAPGIHFYTLNQAEPVLKICRALQAQ
>A0A518LLW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium RAS2|TrEMBL
MRIRELLSTGRPCFSFEFFPPKTDNGLEQLRATVRALRDLSPTFISVTYGAGGSTRDRTI
ELVSEIQRHYGVEVMAHLTCVGSTRDELAAVIDRLVGAGIGNILALRGDPPKGDVAFRPV
ADGFHFANELAAFIRAQNRDICVGGACYPEGHVECVGSDGARDANRDLENLQHKVEAGAA
FLITQLFFDNSHYFRFVDRARAAGIGVPIIPGIMPITNVEQVRRFTQMCGATIPQTLLTE
LDRLKDDEDAVLSLGVAYATAQCLDLLNRGAPGIHFYTLNKSAATRTILTALRTLWPPAM
RPA
>A0A369HC91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps camponoti-saundersi|TrEMBL
MHIKQMLVEAENGHQPSFSFEYFPPKTAQGVQNLYHRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQSVCGLETCMHLTCTDMGLDKVNEALSKAYKAGCTNILALRGDPPRDQKM
WTATDGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVGRVRDRGITIPIIPGIMPIATYASFIRRANHMQCTVPSQWMDAL
EPFKNDDVAVREIGKTLVAGLCRKLLASGIHHLHFYTMNLAQATRMVLEELQWAPCPERP
LHHDLPWKQSKALGRQHEDVRPIFWSNRISSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRNKWGAPKTVRDVANTFVRYLDQEIDSLPWSESPLTGEADLIRSNLKA
LNKRGLLTINSQPAVDGAKSSHPIHGWGPSNGYVYQKAYLELLVPPDIVEDMIRRIEDRP
SLSYYATTKDGDLMTNVCTEGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGIDW
GHCFDEGSPSRALIDKIMNEWYLVNLVDNDFRNNSAIFDVLDNLQVKDLDIVYAA
>A0A1G1Q218|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium RIFOXYA2_FULL_45_12|TrEMBL
MTFKEKIQAGKFILTSEVGPPKGIESGRILEDVELVRGRVDAINVTDLQSSVMRLGSLAV
SIRLKEKGFEPVYQVTCRDRNRLALQSDILSAANFGIENILALTGDHPKLGDHPHAKAVF
DIDSVQLIQVIRRLEQGLDMAGKKLEGVLPKFCVGAVVNPGSDPLEPQIMKMEKKIDAGA
EFFQTQAVYDLKSFENFLSKTKHLKTTVIAGIVLLKSAGMAKYMNENVAGISVPDNLINE
MRDTKDKQAQSIEIAARLIKELKPMCQGIHIMPIGWDKLVPKVLDAAGL
>A0A2P6RHT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rosa chinensis|TrEMBL
MKVIDKIHEALADEKKVVFSFEFFPPKTEDGVENLLERMDRMVAHNPAFCDITWGAGGST
ADLTLDIANKMQNMICVESMMHLTCTNMPVDKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQIQGGFACALDLVTHIRATYGDYFGITVAGYPEAHPDAIEADGLATPESYQSDLAYL
KRKVDAGADLIVTQLFYDTDVFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIRTLHLYTLNMEKSALAILMN
LGLIEEAKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDLYPHGRWGDSRN
PSYGALTDYQFMRPRARDKKLVEEWVVPLKSVEDIHEKFEKFCLGKLRSSPWSELDGLQP
ETKIINEQLGKINTKGFLTINSQPAINGERSDSPSVGWGGPGGYVYQKAYVEFFCSKEKL
GTLVDKCKALPSLTYMAVNREGSWISNISRTDVNAVTWGVFPAKEIIQPTVVDPASFMVW
KDEAFEIWSRGWGRLYPESDSSRKLLEEVQNSYFLVSLVDNDYIHGDLFTVFANF
>W0DLQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioalkalivibrio paradoxus ARh 1|TrEMBL
MHHHSNTRPAFSFEFFPPKNPEGAERLRRARARLTALDPAYFSVTFGAGGSTRDRTLETV
LEIQNEAAVAAAPHISCISSSRAQLLDLLTTYRDHGVRRLVALRGDLPSGTGVGGGLGEF
RYAAELVAFIREQFGDHFTIEVAAYPEFHPEAVNAEKDLEHFRQKVAAGADAAITQYFYN
PDAYLAFVERVRAMGVDIPIVPGIMPITNYSQLARFSDACGAEIPRYIRKRLEAYGDDTA
SIRAFGVEVVTRLCQRLLDDGAPGLHFYSMNQAAPSEAIWNNLGLAQPR
>A0A2M7ZM32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium CG_4_9_14_3_um_filter_36_18|TrEMBL
MKVIEHIVNAKNPLISFELIPPKRGGDIKSLLAVLDEIIKYNPPFIDITSHSAEVIYEET
PKGIKKKVKRKRPGTLGICALIQNKYNIEAVPHILTKGFTREETEDFLIELSYLGIENVL
AIRGDDSGYDKPIPEGRSKNTYAVDLVKQIVDMNHGKYLEEGLLDARASNFCIGVSGYPE
KHFEAPNLKTDILHTKQKIDQGAEYVVTQMFFDNKIYFNYVDKCLKAGIDAPIIPGLKII
TNKAQLQTIPKNFYINIPDELSDEVYAAKPEHVMSIGVEWATKQVEELLNKNVPSVHFYI
MLDSRPITMLMKRLKLF
>A0A511T5E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcus fulvus|TrEMBL
MNPSNPCFSFEFFPPKTDEGVANLLRTLEDLAPLEPGFVSVTYGAGGSTRDRTLELVTRI
KQQTGIEAMAHLTCVGHTREELRDVLQRLADAKLDNVLVLRGDPPQGQTTFQPTEGGFSY
ASELVQFIREEDFNFCLGGACYPEGHVETASRDDDLRHLKAKVDAGLDFVVTQLFFDNAF
YFDFVERARRAGINIPIVPGIMPITNYEQVQRFTRMCGATVPMRLGLQLERVKDQPEALV
QLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRAHL
>A0A0V8I6L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter enclensis|TrEMBL
MSAEPEASSTGGLNSGHSALIDGYSLEMTGKDVPGLLEAKESIPAGTRINVTFLGNESLE
MRLAAANSVRELGFVPVPHISARRISSQHQLEEFLDALHQARASENVFIIGGDPARPEGP
YEDSSDLIRTGLLTKYGVKQVGIAGYPEGHPDIGHEKLWNALTEKTTLLKDQGLESSIVT
QFAFDTDPVIDWIEDVRALGITSEIRVGTPGPAGIRRLLGFARRFGIGANAMIAKKYGFS
LTNLMGTAGPDKFVTELSERLDPTMTTGPVKLHFYTFGGLEATSNWAKRYKTQRQN
>A0A512L3D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuriferula plumbiphila|TrEMBL
MNMVKRTFSFEFFPPKTPQGIDKLRATRDQLALLKPKFFSVTFGAGGSTRDHSLETVLDI
QRAGYSAAPHLSCIGSTHDNIRAILQEYQTHGIRHIVALRGDLPSGMASTGEFRYANELV
EFIRNESGDWFNIEVAAYPEYHPQARSAREDLLNFKRKVEAGANSAITQYFFNADAYFNF
VDKCAALGVGLPIVPGIMPIGNFTQLARFSDACGAEIPRWMRKQMEAYSDDIESIRAFGL
DVVTDLCERLLKAGAPGLHFYTLNQAALTTAIWQRLGL
>A0A3A4RZK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MMQRKSVMLRIFNHEIQNPDHFVVTVELVPARESGGRTTDTIVGIAKDAFSDGRVCAVSI
TDNPGGNPSLSPDVLGYEIYKHGLDVIVHFTCRDMNRMGMESRALQLARMGMKNILALTG
DYSGKGFGGQGKPVFDLDSTILCSLLRSLNGKLIASGDPEEFFFGCAVSPFKTTEAECRA
QYTKLDRKIEAGASFVITQLGYDAEKYSELMTDHQRKGHTVPVLGSAYLLSPRSAGAMFK
GKVPGAYLSKALYETVMKEWETPRQGLKAAIERTARLGVILKGLGYRGIHIGGVHKSFHT
VGAILDRMDEIQVSWQDYLHEFNHNRRQTYYMFADRKADMNTPSTKTRLKSRLVDFLPYT
VLHTTHNLFFNKNSPLAPFFRTVAAMIDRNGKAWLLKLLLEDPIKIPLLSCQGCGDCGIQ
HAAFLCPESGCPKHTRNGPCGGSREGYCEVNQEKLCIWVRAYSRLQYGRATEMFIHKFVP
PRNWALNKTSSWINFHLGRDHQKEMVKK
>A0A101WU27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vulcanisaeta sp. JCHS_4|TrEMBL
MTVLIIELPPLRRIDNLDNYLEMVNSVVDYATHIDIPDSTFANPSANAVLIGSLIKHRFS
NVEVIANVRVADHNKVGLTALIMGGLANGVRNYLLMRGDLGPGVTAVPDLTPISAIGYLR
GVEQVKGARLGVSISSFDEKYIRDRLEARPDFAMLQYTLSMDDLIRTAEANREFGVDIYP
ALLVITNKSARTISRILNTDIPVPQDPISDAVRRAREILEHFPGVYISAPGDFNAIVETA
RAMHKYL
>A0A831KS20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSNTRSLKKTLQQGHFAVTAECGPPKGADAEAVLQKAELLRGKVDAINVTDNQTAIVRMC
SLASCALLKSAGLEPVLQMVVRDRNRIALQSDILGASALGIENVLCLSGDHQVFGNQPQA
VGVFDLDSIQFIQTVRAMRDEGIILGGEPLTKPPDLFIGAAANPFGDPMRFRVVRLAKKI
QAGADFIQTQCIYNLGRFEQWISEARDRGLTEKAFILGGVTPLKSAGMAKYMKNRVAGMD
VPDDVIKRMETVPKDKQREEGIQICVETIERLKEMPGVSGVHIMAIEWEEAVGEIVQRAG
LLPRPEAE
>A0A6H3NRZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira bandrabouensis|TrEMBL
MNQILLEVVPRDVPTLLSDVHYVKNNFSQISGINIPDLLRFETRSWVAATTIQSIFPNVI
PHLRAIDFDIDHCDYLIEFLQKNNLSSVVVIKGDPPTDMSRKVYPTTSVKLIKKLKKEMS
SLKVYAAVDQYRGSIKDEFDYIEMKIDVGADGFLTQPFFDLRLIDIFTEKLRGKKVYIGI
SPVITEKSQSYWESRNRAYFPSNFNLSMDWNVQFAKDVIRYCSDSDFNMYLMPIKIDLDV
YLSGIFKS
>A0A7C0V493|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSANGLKSGSNLEKILKAGHFAFTGECGPPKGANVEHLREKYAHLRGVVDAINVTDNQTA
VVRLSSMASCALMVADGLEPNFQMVCRDRNRLAMMADIFGAYALGIRNMLCLSGDHQHFG
NHPQAKNVFDIDSMQLIALVRKLRDEGKFPNGDEVDGPPRMFIGAACNPFGDPTEFRVHR
LANKVDAGVDFVQTQCIYNMERFRQFMRQAVDMGLAERCYILAGVTPMKSARMAKYMAKF
VPGMDVPEALIKRLEGAEKGKQAEEGIAAAIEQIQEFKEMPGVAGVHLMAIEWEHKVPEI
AQRAGVLPRPEV
>A0A7W0IXF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MRATRLYENKKPVISMEFFPPRTEKTIQAFGTVIDQLAVHQPDYMSVTFGAGGSTRDGSY
QTVKQILEEKNIPTVAYIAAFGLGPEDICKVLDSYKNLGVETIFVIRGDEPKEEGFTPHP
DHFPNASGLLAFIKKNYDFTLGCAGYPEGHLEAQSPEKDLKFLKLKIDNGAEYIVSQYFY
DNDFFFRYVEKCRKLGIHVPIVPGVMPVYTLGMTRSLSQVCGSSITDALNAKLQAVDPKD
SEAVLNLGIDFAVDQCRGLLKAGVCGLHFYTMNRSKSTGEIISQLKKESLLPA
>A0A2T4TEL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium oral taxon 096|TrEMBL
MHNQGKVSIREFLQNNVLIFDGAMGTYYSSIVNEPAINCEMANIQHPEVIESIHKEYIAA
GAHAIKTNTFGVNRKNFGENSKLLEQLVDAAVEIARRSANDTTYIFADIGPIDGEEEEKV
VEQYKEVVDLFLKQGINDFLFETNSSITGLFETARYIKEKSPEAFIINSFAVLPDGYSSE
GRYYRKLLSRNEENASVDILGLNCVCGPAHMLTLLENVHTTDISIMPNAGYPVVRGRRTF
YSNGPTYYAEQLENIVKRGVQIVGGCCGTTPAHIKAFVERLGSTSFVRQKIQPKSVVVTE
EKNESKNHLWRKLEEGKKVIAVELDSPKNADLSGFMESARRLQAAGVDTLTIADCPIAVA
RMDSALLACKVKRELGLDVIPHMTCRDRNINAIKALLLGMHAEEIYNILAITGDPIPNAQ
RNEVSSVYQFNSRKLAAYIDSLNAEVFDEGYKIYGALNVNARNFEVELRRAEQKIEHGMV
GFLTQPVLTQEAVENLAKAREQLSAKILGGIIPVVSEKNARFMDSEVNGIRVSEEIISQY
VGKNREEGEQLAVEISLDMAKKIKSYIDGYYLITPFNRVALMEKIIEGLRE
>A0A8I0V9Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. SK-43|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIQRFVEKVQAGANAGITQFFFNPDAYFYFI
ERLAKSGINIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A3A4QEG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSVKTPSKLEKIFSLGHIAVTSECGPPRGSDPEAVKEKGALIRNHVDAVNVTDNQTSVVR
LCSLAACIHLKLIGIEPILQMVSRDRNRIAIQSDILGAASFGINTMLCLSGDHQSFGDNP
KGQNVHDLDSMQMLQTVRLMRDEGKFLGGDDIKTPPSIFVGAAANPFADPFEIRVPRLAK
KIAAGAEFIQTQCIYNLNKFEKWMELVRDKGLDEKVHIMAGVTPLKSAGMAKYMKNRVPG
MDVPDDVVDRMAKTPKDKQAEEGINICVETIQRLKEVKGVHGFHIMAIEWEERVPEIVER
AGLYPRPDIA
>A0A3A4SYU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSAKTPSKLEKVMAAGHIGVTSECGPPRGTDPEEVRKKGMLLKDHVDAVNVTDNQTSVTR
MSSLAACIHLKLMGIEPVLQMVTRDRNRIALQSDILGAASFDVFNLLCLSGDHQSFGDNP
KGQNVHDLDSMQLVQTVRLMRDEGKFLGGADIHRPPKMFVGAAANPFADPFEIRVPRLAK
KIACGAEFIQTQCIYNLDKFEEWMKLVRDRGLHEKVYIMAGVTPLKSAGMAKFMKNKVPG
MDVPDDVIKRMAGVPKEQQPEEGINICVETIERLKAVEGVKGFHIMAIEWEEKVPGIVER
AGLYPRPEIGTEN
>A0A3A4WM76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MVSKFKEALRTKDFVVTCEVAPGKGTNLEKMKHHIELLKDRVDAINVTDHQSSVMRYPSL
GGALLIKEMGGEPILQMTCRDRNRLALQADLLFAASRGIHNVLCLTGDSVMLGDHKEAKP
VFDIDSSQLLMTIRGMEKGKDMAGNDLDGKVSFCAGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVYDLDKYKRFIEYALQFPVKILAGVILLTSAPMARFMNKNVAGVNVPQELID
EMASAPKGRAIQKGIEIAGRMITRIREEKMGHGVHIMAIGREELVPDIMAAAGLT
>A0A523R4K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSFQKRLTSGDFVVLAEMNTPKGVDISELVTNVRRIKGRVDAVIVPDMDNGIMRMSALAG
GVLMHQQGVESIIHVYCRDRNRMALQGDILAAHVLGIQNLVVAHSEEMAKGDHRDAKPVN
DIDELELLGAIQSLQEGVDMAGFELSGSPSFTVGCTIAPFGDDAALEKELSFAGEKIKAG
AQYVITPPVFNLDHFASNMEKIKGLGVPVISTVFLIKSVGIARYIANYEPGAQISEDLIK
RIRKAPDTETECLRIAGETVAGLKELSQGVQIVTLGWEYRLPVILDYAGI
>A0A2N6CDM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLEKVLKAGHFAFTGELGPPRGCDVEEVIEKAQHLKGNVDSVNITDNQTAMVRMS
SWAASLLLLQEGLEPNFQMVCRDRNRLAMQADVLGAYAHGIRNMLCLSGDHQMFGDHPLA
KGVFDIDSIQLINMVKIMRDEGQFLSGADLHGSPKMFIGAASNPFADPFEWRVHRLAKKV
NAGCDFIQTQCIYNMDKFREFIKQANDMGLTEKTYILAGVTPMKSVGMAKYMKNKVPGMD
VPDEIIKRLQGAGKGKVADEGIKFACEQVEEFKEMKGVHGVHMMAIEWEHMVPEIAERAK
VLPRPVMD
>A0A395VQJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides ovatus|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A3A4PPA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKLKEALKRKDFVVTSEIQAPVDQDPEQIVKSLQAIRGRMDGVSLSDTEFQGVVGDTIKA
CEVLQQNRFESIYQTTTRDKNRIQLQNDLLSAHDAGIDNLLVFTEDYRITGDSLQEMMFF
HVDAGKLQSVLQHLRDGHTIDGQELPLRKEFLLGSGVESAWGKNVPDLEMKEMEEMTKIG
TGYFLTTPVFDVDRFEKFLSRTQTFGVPVIAEVMILRTAGMAKFLNRHLKPGLVPDWIIK
KLATATDIEKASIEIFADIVKGLKHLCQGVHIITIGGEEKLRQYLDAAGLK
>A0A0D8KA10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium nepotum 39/7|TrEMBL
MPDISTSPAIAASIEASPAQVLGPANLAGLFPQGVRVYLTDTGQASQERLVDAAKHLRDL
GYTPVPHLAARRISSRADFEEQVKRLAGEAGVSDVLVVGGGVDRPAGPFASSMDMLATGI
FDRCGINHIAIAGHPEGSPDFSEETAMAALRLKRDFAERSDAAMRIVTQFGFDPARFIAW
AEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTTLAKGHSPES
VVGPIERHWHANPAGLIRQIHVFPFGGLQNSADWLIGRGSWQFGDTDCSATLGTVAV
>A0A7C5GAS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp|TrEMBL
MNNKNAASRISRLTREKKPKIELSFEFFPPKTEVSEARFWASLEKLVPLNPRFVSVTYGA
GGSTRERTLRMVSRITQETGINAAAHLTCVGASRGEVEDVVRGF
>A0A6N6RBD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella intermedia|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDVKPAAHLTCVDATREEVDRVVREFAALGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKAEAAL
ELA
>A0A6P1NZG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nibribacter ruber|TrEMBL
MKVTEHLQNATSTLFSFEILPPVKGKSIQSIYEGIDPLMEFNPPFINVTYHREEYVFKER
GNGLLEKITIRKRPGTVGICSAIMNKYKVDTVPHIICGGFSKEDTENALMDLNFLGIDNV
LLLRGDAVKTEAHFRPHTDGHAHASDLIQQVVQLNHGQYLDEEMESPTPTDFCIGVAGYP
EKHVEAPNLATDLKYLKQKVDLGAQYIITQMFFDNKKFCDFVTACREAGITVPIIPGLKP
LTTCNQLTVLPRFFNIDLPEDLVNAVEACKTPQDVKQVGIEWTIQQCKELMNFGVPCLHF
YTMSKSEATAAVARAIF
>A0A7S7Z1J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. CCBAU 53421|TrEMBL
MTETISSLPNGQRAPKAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTISRILRETDLLPAAHLTCVSASRGEIDEIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAGIKRRHADIEISVSAYPEKHPEAADFDADIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPTGA
QKAA
>A0A838N568|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MRIDEVLKNGNGRPAVSFEFFPPKTEAGFASLFKTIDELNPLKPTYVSVTYGAGGSTRAK
TVQLVERIQRELGIRSMAHLTCVGHTSEEIAGILDELWKAGIRNVLSLRGDPQAGQSQFI
ATEGGFANADELVAFVKSKHDFCIGVAGYPEGHPQCLNRTRDLEYLKRKVDNGGDFVITQ
LFFDNADFYRFRDDARAMGIKSPIIAGIMPITNVGQIKRFVSMCGAKIPHRLLKKLESVE
PDAETVHRTGVDYAEMQCRDLLFNGVEGLHFYTLNKSRATVDIVKRLGAEHVS
>A0A8I1U426|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp|TrEMBL
MSTDYTDRPSRMRPDERPKFQVSFEFFPPKTDVMEERFWESIHKLAPLHPRFVSVTYGAG
GSTRERTLRMVSRVKAETGVDAAAHLTCVGATRDEVDAVVRGYQEAGISRIVALRGDPAE
GIGKPFTPHPEGYRNAADLVAGIRRIGAFDISVAAYPEKHPQSPNWEADIDNLKRKLDAG
ATRAITQMFFDNDDYFRFVERARAAGITAPIVPGIQPIHSFKQISGFAARCGASIPGWVA
ERFEGLDEDPETHALVASAVAAEQVLELVDNGITEFHFYTLNRSNLVLALARLLGARPD
>N1MQ25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium japonicum BiD32|TrEMBL
MSLPSIHPNWDLPPKGMTDGYSLEITAKDIDALREAAPAMAPETPVAVTFLPGESLEARI
EAARTVRALGFEPMPHFSARRLESGDDFEAYLAAVVREAGVTRCFIIAGDPPEAAGPYTD
SMSLIRTGAFERAGIRAIGIGGHPEGHPNMTPDQCFDILIAKCAEIEARGMAPLIVTQFS
FDAAPVLAWLAELRARGIVAPVRIGIPGPAGIKTLMRFAARCGVGASASVLTKYGISITK
LIGTAGPDKLVDALGKGLGSQHGKVRLHFYPFGGLARTVEWINDYTKSR
>A0A1G1GFZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium RBG_16_43_11|TrEMBL
MKISQLLQNNKPIFSFEFFPPKTAEGEKNLYETIKNLRHLEPAWVSVTYGAGGSTREKTI
DLVIRIKHELGIEPMAHLTCVNSQEDEIKGILTKLSKNGIENILALRGDMPLQDNSAKQV
HQSFNYACELIQFIRKNFDFCIGAAAFPEGHLESKSIDEDTHYLKVKAGAGADFFVTQLF
FDNRFYFDLVERANRAGVNKPIIPGIMPITNVEQIDRFTSLCGATIPHDLKQSLEEIKEN
PEAVAESGIRYATEQCRELLDKGVPGIHFYTLNRSPATIAILRELKGRR
>A0A091AY37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenimonas oryziterrae DSM 21050 = YC6267|TrEMBL
MPKFSFEFYPPKTDEQRTQLDRTVRKLKAYSPEFVSVTFGAGGSTLSYTPETVRELRQKH
KLNGVPHLSCMGGTREEIRELLSLYKALGCTRLVALRGDLPSGMARMGDLRYASDLVRFI
REEHGDHFRIEVGAYPEMHPQADDALVDLQHFKAKMDAGADSAITQYFFNADAYFRFVDD
VRKLGVTAPIVPGIMPISNFSQLKRFSDACGAEIPRWIGKRMQAYGDDADSIRELAADLV
AGMCRRLLDAGVPELHFYTLNLARPTEAVLSRLG
>A0A5K7ZAM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina widdelii|TrEMBL
MKLTTLFDKGEFVVTGEVGPIKGAVNRDKSIDPTCTQEAKYLQGWVHAVNVTDNQSAVMR
LGSLAASVGLKQKGIEPVYQLTCRDRNRIALQSDLLTAYSLGIDNVLLITGDHIQLGDHK
EAKPVFDLDSVQLIDMAMGLRNGHDITGNEIENPPDMAYGAVVNPNFEPLDLQLMKMKKK
VDAGAEFFQTQAVYDRKVFETFMNKASKLNVPIQVGLVVLKSPQMGKFMNNNVSGIEVPQ
SWIDEIGSVEKEDRKMKAAEMMGRFLAEIKDMVQGVHLMPLGWADIVPKILQTARIAV
>A0A015V1A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis str. DS-208|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>M5GA04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dacryopinax primogenitus (strain DJM 731)|TrEMBL
MKLTEAISRDDASTIHPYYTLEFFPPRTDSGFENLLTRLSRLSVLNPIGLTITWGAGGST
KQRSLDLAEAALGENPVTILHLTCTNMERDMLDDTLDNAKARGIQNILALRGDPPRGEEY
WIPCDPQFQHASDLVKYIRKRDGDEFCVGVAAYPDGHSLDEDAEIANLKLKVDAGADFII
TQLFYDADGFLMWLKKVRESGVEVPVLAGVMPIQSYASFLRMTKLCASRVPPSLIASLEP
IRHDDEAVKEFGVEFATDMIRTITSPNHNGPTVQGIHFCTLNLEKSTWRILDNLGWIGTT
AHVLDEGKNRLIQPDSNVRPSSASLLITPHDAASAATPKEAEDTGPISHTTTTLPALPAN
QAVTWDDFPNGRFGSADSAAFGVRDPYKNELGMTAAEVHRLWGQPETIEDLNAMFLKHLR
GHSPFSTTPWSPNPIAAETKFILPRLIEFTSKGTWTVASQPAVDCMPSDDEVFGWGPKDG
FVFQKAFCEFFCEFVTLERLKHKAAALDTVKFFAANAKGEMMTNMAPGESNAVTWGVFPG
KEVMQPTVIERSAFQAWAEEAFGIWSEWALFFPPASTTRQLLERVRDERWLVSVCHHDFK
NPNDLWDLLLET
>A0A267XF70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. 7788|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEEEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSIEEIKR
SFREQLYILLNEQPDGLLLETYYDMEEAKAVLQIARKETPLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPILENSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHIHAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAAEKRTIIVELDPPKKLNFEKFLVAANELKNAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFVSQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMAKAGEDKEKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKESNIHVNYH
>A0A7X4BPD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MVKNNFIEALAHRILVCDGAIGTELRKRIPSHLQCVDACNISTEHAEKVAAVHRAYIDAG
ADLIQTNTYQANREALAVHGLAEQVEEINRTGVLLARAAAQETCYVAGSVGQISFQTLET
PVPSTKAIRRLFKEQMDALVDAGVDLLVLETFVSPKQAEIATKQALTYGVPVVVEISGVS
GGTVGAGLDVRVFAQELEQLGAHAVGINCRGPHDLVEAMELLAPVIKTPIAVQPNAGNPR
VEQGEIALSYTVEAEVFRDYVGKLVELGANMIGGCCGTTPTYTAKIRQAVAGRKPIKREQ
RIFVLPKITSTSKSPTDNPVQQVFETRKRIVSVEMRANTFPQLRAMLKEAKNLAAIGVDL
FDVTDNSGAAVNIGAIATAYRLQQATQIPTLIHWTTRSRNLISMQSHLLEAETLGIRGIV
ALSGDHPKAGPYETASLVPDVRGAIQLMELINRLNHGELTDGSSIGEPCSFYYGGGFTIA
ENLQPHVKHLTNKVAHGARFAYTQPVWTYEDIVRAQQATEHLDIKVLYGILPLTSFRSAS
YLRDNLGLYIPQFIVDKFRDLEDTAGHELGMKLSLELVQEIRNQDESPIDGIYLIPPARM
NWKNRARVISEIVKAYR
>A0A1H0DLF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacillus sp. OK028|TrEMBL
MGKGGYWMGLLEKLETSILTADGAMGTLLYSYGIDYCNEELNIQKPEIIEKIHQDYIAAG
ADIIQTNTYGANAIKLARYGLENQVKEINEAAIQIAKRAAAPGNQFVLGTIGGIRGIRKS
DATLQEIIHSLDQQALNLLAGDPDGLLLETYYDLEELKTTVTHLRKLTDIPIIAQVSMHD
PGILQNGLSLNEALHQLEAIGANIVGVNCRLGPHHTIQAFEGVKLPEKAFLSAYPNASLL
DIDEGKIVYESDADYFGKAALYLRDAGVRLIGGCCGTTPKHIEAVKKHIGHLTPITNKVV
TKKKPIIIQDAKPTNTKPLHEKAKTERTIIVELDTPRHLDTTTFMEGAEKLYAAGIDAVT
MADNSLASPRISNMAMGSMLKYENNIRPLAHITCRDRNLIGLQSHLMGLDALGIHDILAV
TGDPTKIGDFPGATSVYDVSSLELLQLIKQLNEGISFSGKSLRKKANFSVAAAFNPNVRV
LDRAVKRLEKKIECGADYFITQPVYSKEKMHEIYEATKHLSTPIFIGIMPLTNSRNSEFL
HNEVPGIKLSEEVLERMRLCGEDRERATAEGIQISKELIDTAAELFNGIYIITPFFRYDM
SLELIHYIKEIDRKKERGFSYVQTSN
>A0A848DCN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia bannensis|TrEMBL
MRGSRTEHEGVLADLLTRVRYEVIPTPSIEEKVLAAVPRHLTVTVTASPAKGLEATLALT
ERLRAHGYRTVPHLSARLIRDEVHLAEIVDRMCRAGVEDVFVPAGDADPPAGRYDAALPV
LAELTRAGRPFRRVGITGYPESHPAIGDDLTVQAMWDKRVHAGYIVSNLCFDPAALATWI
ARIRRRGVILPVQLGVAGPVETAKLLATATRIGVGESTRFLTTHTSWFARLARPGGYSPE
RLLRRTTRMLAGPGSGVVGLHLFTFNQVAEAERWRQRQLGELCGRSAAHVGSTRSGR
>A0A3N6M141|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natrarchaeobius chitinivorans|TrEMBL
MPRNPGVPEQRDAVQTLLEDVTFDLNSIDSFEQALTNIPDGETIAVTLAPKNGIEPTIER
SVSAATQGYDVVPHIGARFISDRDELDEIAQRLLDADITNIFVPGGDLDEPVGDFSSAYE
LLVALDELGHSFEEVGIGGYPTGHEFLEDSVLRSAMEKKKAYATYIVTQLSFDSTAIIEW
INRIRNRGIELPVEVGIPGVMNYWQLMSLCRRWGIAEPLQFLRKTTGFVGFATELIRAKG
KYKPDELIDDLSAYVDDEQFNIGGLRLYTFNQTATTEAWRQSRLNGA
>A0A495ZER9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MATTSRKKDNFMEALAHRILVCDGAIGTELRKRIPAYLQCVDACNVSTEHAEKVTAIHRA
YADAGADVIQTNTYQANREALTVHGLAEQIEEINKTGVFLAREAVPETCYVAGSVGQVSF
QSLDTPAPSTKTIRRLFKEQMDALVDAGVDLLVLETFVSPKQAEIATKQALTYDVPVIVE
ISGVSGGTVGAGLDVRVFAQELEQLGAHGVGINCRGPHDLVEAMELLAPVIKVPIVVQPN
AGNPRVEQGEVAVSYTVEAEVFSDYVGKLVELGANMIGGCCGTTPVYTAKIRQAVAGRKP
VERESRIFVLPKIRSVGGSSLGVSSRSPRPYDNPVQQVFETRERIVSVEMRANTFPQLRA
MLKEAKGLAAMGVDLFDVTDNSGAAVNIGAVGTAYRLQQATQIPTLIHWTTRSRNLISMQ
SHLLEAEALGIRGIVALSGDHPKAGPYETASLVPDVRGAVQLMKLIARLNQGELADGSSI
GEPCGFYYGGGFTIAENLQPHVKHLANKVAQGANFAYTQPVWTYEDIVRAHQATEGLGIK
ILYGILPLTSFRSASYLRDNLGLYIPQFIVDKFRDLGDTAGYELGMRLCLELVRDIRNQD
ECEIDGIYLIPPARMNWKNRARVISEIVKTYRQ
>A0A1Y1IZ67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas testosteroni|TrEMBL
MKKALDAQQFVCVLEWTPRDNKASAASLHQLMEHQQLAGMPLVAALADRVGQNAQLSSLA
SFERHRGPFPTLLHFSGKDRAPQQLQAQLEQMQEFGLHDLLLLSGDRDPTHTPGQRSVRY
LESVPALQQARHQLPGASLGAALNPFKYLEEEGIAQYYKAHKKLIAGADFLTVQLGFDVA
KYDEAWQWMHKQVSPKPLMACVMALTHTRAQFLRHVPGVVITRSMMDLLAAEEQQGADWS
RQRSTERLALQILGLQLKGYAGVHLSGIHGQTQFSELENALERLLGNIETQEQWREAWAS
LWQYPGTGKVNFAPEESDWAPGLERVQASIGELRRFHRLQALHHLFFSEQSVLGKALGSV
MRWPLWQSPIAARILHRVERGIKRPVLGCDTCGHCRLEQTLYVCPETCPKGLANGPCGGT
HLNRCEFGDRECIHSVKYRISVSAQQSQVLREVLIPIVPEQTRHQSSWPRWFRPDDVI
>A0A7Z9YCR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MTKLQESLQQGKFVVTGEIGPPKGVNLETALKEASYLKGRVVAVNVTDNQSSVMRLGSLS
MCAKLIQEGYEPIFQVTCRDRNRLALQSDILSAYVLGIRNILALTGDHTSLGDHPQSKPV
FDLDSVSLLMAISALKEGKDLAGEELDGAPSDIFPGATVTPGADPLEPQIIKMEKKIEAG
AQFFQTQAVYDPKTFERFMDQASKFNVPVLAGIVIIKSPAMARYMNENVPGVFVPDPIIK
ALAEVPRKERAKKSIELMAQIIKELKPMCQGIHIMAMGWERYVPDLLDACDLS
>D3G024|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalophilus pseudofirmus (strain ATCC BAA-2126 / JCM 17055 / OF4)|TrEMBL
MTFIEKMKNEVLVGDGAMGTLLYEQGISKCFEELNLSDPNRIIDAHKQYIEAGAVIIQTN
TYAANRLKLEKYGLGEKVKIINQEAVKLAKEAGPNGIFIVGTVGGLQNFHQEEWTKEEVL
EALEEQIEALLASNVDGILLETFYDLDELLGAINIVRNQSELPIIANVSLGEIGVLHGGV
SLKEAIGELEKAGADVVGVNCRMGPSHMLRSLEDVPLPKRAYLSVYPNASLPEYQDGRLF
YHSNPEYFESMGEQFVNQGVRLLGGCCGTTPEHIRAFSQVAERRTPVEEKWVTPSLEKVT
KKIEFPRSLVPLSDIAKKRRSVIVELDPPKKLSTEKFIKGAKVLKEAGVDAVTLADNSLA
SPRIDNMALAAQIKEDVRPLVHVTCRDRNLIGLQSHLMGLHALGINDVLAVTGDPTKVGD
FPGATSVYDVTSFQLISLMKQLNEGISFSGKDLGQKANFSIAAASNPNVRHLDKAVQRME
KKIESGADFFMTQPMYSEEQIEAFYHETKHLDTPIYVGIMPLTSSRNAEFLHNEVPGIKL
TDSIRRSMASCETKDSAQLEGIKIAKSLIDTATQYFNGIYLITPFLRYEITAELTAYIEQ
KSTAKLMN
>A0A0S7YWN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium SG8_13|TrEMBL
MPADSFTITVEVVPPAGSASEPILSALGSLTRLAFDGFSVATNPVAKPRMSAMALCMLIQ
QKTGKPAILHCTTRDHNRISLQGLLWGAVALGIEAVLAATGDFVALGDRATTTDVRDIDV
FELVGMSRAAGMRTGVVLDPRPESGGLMREVRRLERKIEAGAQFVVTQPVYDEASADELA
EALRRVTIPVVMGVLPLRTAKHAEFLHRKVAGIAVPERVRQRMHDAANPVAAGAANAIDM
LTAARQRFSGVCIMPPFDHYEMLFDILEEDR
>A0A1M5I1K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marisediminitalea aggregata|TrEMBL
MVSYAQGVDALNQSLSELRDIDVSFEFFPPKTESMEKTLWKSVERLAPLNPSYMSVTYGA
NSGERDRTHDIVKRIQQQTGVTAAPHLTCVDATKDELKQIAKDYWDSGIRRIVALRGDLP
QGVEKTDMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDASVYLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGYLHKMFEGL
DDDDQTTRNLLGANIAMDMVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRANGN
>A0A0U3FXR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium limosum|TrEMBL
MTIPEIMKNRMSFSFEVFPPKEEQPLEPLLDTLDHLYAFKPDFISCTYGAGGTNAGRNVE
ICKAIKDSGATIPITHFTCIGNSKDKIRDELRNYLSLGVDHILALRGDFPKGSASTGGDF
DYANELIAFIKEAFPEFSIAMAGDPEKHFEASSFDEDITHLRIKQDAGADFIMTQLCHDV
AHYEWWVEKIRKAHITLPIDVGIMPVLAKDPTIRMAVSNGSSIPRDLAEIIARYGDNSKD
FKKAGVEYTVKQIHRFISAGIDGLHIYSLNKWADISEIVRAAGIR
>S9QAG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger mucosus DSM 16094|TrEMBL
MRGAPLIPEPTDALLRRLVESRGAVPLGFELFPPRSAERREALRETVERLAPVAGKGFSV
TMGAGGTTRTGTHDTAVEVARIAGRPVTAHLTALGLSREDALAAAEGFWEAGITRILALR
GDRPRAVQGPLPPGFAHAADLVAALRDCHPFEISVAAYPEKHPEADTLEADIDHLKAKLD
AGATSAVCQFVLDPEAYGRFLETCARHGIDAPIVPGLMPLEGWSRLRGFARENGAHVPDW
LNHLFSQAEQAPETMPYLSAVATVEQARRLVGYGAPALHVYAMNRWPLALALARLLGH
>A0A2D8Q6Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tistrella sp|TrEMBL
MMTVTTDGRVLTPQALWDAPAPVPGLKISLEFFPPRGAQAEARLWENVARLAAYAPDFVS
VTYGAGGSTRDKTRDTVLRMRRDYGLAAAAHLTCVDASRADVMAVAEGYIADGIDHVVAL
RGDPPQGAGPYVPHPDGFPFAVDLVRALADLGRFEISVAAYPEVHPQAQSAGADLDNLKA
KLDAGATRAITQYFFDPAVFLRFRDRAAAAGITRPILPGLMPVLGFQQIKRFSAACGAGI
PDWMERLYDGADADEATHQAVSAMLLAEQARVLAAEGCADLHFYTLNKAELTISACHLLG
IRPRAEVAAARAAG
>A0A372J6B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus sp. LHW52908|TrEMBL
MTRTVRDLLAEGRPTWSFEFFPPRTPEGAEQLWTALRQLERLQPSFVSVTYGAGGSTREG
TVSVTERIATETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WVPHPEGLRYAAELVELIRAMGDFSVGVAAFPERHPRSPDFETDVEMFVRKCRAGADFAI
TQMFFRAEDYLRLRDRVAGRGCDVPVIAGVMPVTNARQITRIVQLSGQAFPEPLAARFAE
LDGDRPEDRAAVRAYGVEVATELCRTLLAEGVPGIHFITMNRSTATREVHANLTAGPAAR
DADLAAVPVTS
>A0A523Z263|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MPSQNLFNEWLASGEPILADGAMGTMLHARGISFNVCFDDLNLSQPTLVADIHRAYLDAG
AQIIETNSFGANRFKLAEHGLERRVGEINAAAVNLARQAVATSNKDALVAGSIGPLGVRL
APFGRVKPEQAYDAYHEQIEALIQAGADLLIFETQNDLYEIREAIRAARTITDLPVIATL
TFTRDDRTLLGDSPRRVAQVLVESGAQVIGANCSGGPAQLMRVLQQMRAAAPETRFSVMP
NAGWPERVAGRIMYPATADYFADYAIQFCQAGASVVGGCCGTTPEHIANMRAALDAADKP
RLAPEPLLFESAASPTGPSEHPPTELADRLAGGRFVISVEMDPPRGFSTHKMLAGAHLLA
EAGADVINVADSPMARMRMSPWAVCQLIQRDVGIESVLHFPTRGRNLLRVQGDLLAAHAV
GVRNIFVVMGDPTAIGDYPDAMDDFDLVPSGLIKLIKQGFNTGIDHSGADIGEATSFFAG
TALNLCAQDPERELRVLRKKIAAGADFILTQPVYQPDLASSFIDSYRERFGEPPIPIIVG
VLPLYSKGHVAFLHNEVPGIHIPPHFQRRIEQAGDKAADVGVEIAVDLLAELRQSVQGAY
IMPPFGRFDLAAEIIEAIRGVKPS
>A0A2B3KRY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2B9Q1Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRIYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKSHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDTAMKYFNGVYLITPFLKYEITEHLVKYVR
EKQDVKEGIN
>A0A4Q4IMC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporolactobacillus sp. THM7-4|TrEMBL
MKTPVLNELKKRILIGDGAMGTLLYSYGIDRCFEELNISHAEEVRHVHEAYINAGADVIQ
TNTYGANAIKLARYGLEGEVRNFNKAAVRIAKRAARPETYVFGTIGGIHGFQNQSPDYHE
IEQSFLEQADCLIDSGVDGLLLETYYDFDELRRVLVLARKVTDLPIIAHVSMQEPGVLLD
GMPLSKALEELENLGADIVGTNCRLGPFHMIQALQGIPLPKRAFLSAYPNGSLPDYRDGK
LYYESEPGYFKKYAAEFRNEGVRLLGGCCGTTPVQIEAFKQGIAELEPLETKTVRVHERA
IVIDHPDIHPETPLYEKAISGRSVFVEFDTPRHLNTAHFFKGVKALEEAGADAITMADNS
LASPRISNTAIGRLIKEKFTIPPLIHLTCRDRNLIGLQSHLMGLEVLGLHDLLVVTGDPT
KIGDFPGATSVYDLSSIQLIELIKKFNRGISLSGKSLKHPTHFRVAAAFNPNVRNLDRAV
QRMKRKADSGADYFITQPVFDKQRIIDVSEATRDVSAPIYLGIMPLTSSRNAEFLHNEVP
GIRLPDDVRKRMAAAEGEEARRAGIEIAKELIDTAMKYFRGIYLITPMGHYTMTAELIKY
IKEKERFLAGTVISKANRIFQD
>A0A2B1JSP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
TQEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFHGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A669EKL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oreochromis niloticus|TrEMBL
MVNQVQRGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRYFWPPVQLSLTPLPDCGCYVCVPVYYLTPIPGLSVPLC
FFYRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQSK
EKITGYLAKAKHLGLKNIMALRGDPVGEDWEEEEDGFNYAIDLVKHIRSEFDDYFDICVA
GYPTGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFLKFLDDCRAIGITCPILPG
IFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNYGIQQAVEMCRVLLDSGKV
PGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYI
YRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLQMWGEELQNEESVFEVF
TSYITAQPNHCGHKVMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTD
PIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVNGRNLTNAPEMQ
PNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWGKLYEDESPSRMIIKYIHDN
YFLVNLVDNDFPLENCLWQVIDDMFELLDAPPELHSEETV
>A0A2A9W576|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTLKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKSHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHEMKEAAIEEGIRISQELIDAAMKCFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7W3TKQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter spongiae|TrEMBL
MSTPHRTPISFEFYPPKTDEQRTQLDRTAAKLKAAGPEYVSVTFGAGGSTLSHTPEAIQH
LAARHGYSAAPHITCMGGSRQEIRGMLKLYKAMGAKRLVTLRGDLPSGMVSPGDLRYANE
LVEFIRDETGDHFHIEVAAYPEMHPQARDAHADLAHFKRKVEAGANGAITQYFYNADAYF
RFVDDARAHGIDIPIVPGIMPISNFSQIRRFSDMCGAEIPRWIAQRMLAYGDDAASVRAF
GADVVAELCQRLITGGAPALHFYTLNLAKPSLSVIERLA
>A0A7L2LJN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hippolais icterina|TrEMBL
MVNETQQTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
FIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6L5LMM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEVTKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>V0AE93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 909945-2|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2S4ZZT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solitalea longa|TrEMBL
MKITEHLNNAKKPLFSFELLPPMKGQNIDQIFEAIEPLMEFEPPFIDVTYHREDFIYKKQ
ANGLLEKVSTRKRPGTVSICAAIQFKYKVDAVPHLICGGFTKEDTENALIELKFLGIDNV
LVLRGDARKEDGGFIPEEKGHAYASDLLQQVVNMNKGRYLHDEYTGANGTNFCIGIAGYP
EKHFEAPNLKTDLRYLKMKVDMGAEYIVTQMFYDNEKYASFIKLCKDNGINVPIIPGLKP
LTTKKQLTLLPKVFNIDIPEELADAVADCKTDKEVKEVGIDWCIQQSKGLIELGAPCLHY
YTMGKSDTIKRIATAVF
>A0A2S7A8V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola|TrEMBL
MDPDTPSLAGTLTEAYSLEVSAKHIAGLAAAAPRITRGATIAIPYLPNQDDDARLAAARM
VRALDFQPMPHLSARRIASREQLHAFVSRAVDDAGVECCLVIAGDPPAPLGPFPDSLSLI
DTGIFERSGIRTIAVAGHPEGHPSMPAADRWEVLQRKCRSIAERGMAPLIVTQFAFDADI
VLTWLQALRARGIAHPVRVGVPGPAGVAVLARYAASCGVGACASMLSKYGISLGKLLGTA
GPDRFVERLATGLTDAHGEVRMHFYPFGGIAQTVAWVEQYRTLTARVQAD
>A0A5Q4T218|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. t39|TrEMBL
MALGTASTRTDRARTVRDMLATGETTYSFEFYSPKSDKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRAGTVKATQKIASDSTLTPVAHLTAVGHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMADWVKHPEGVTYAAELVSLIKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVD
KCRAGADYAITQMFFSPENYLRLRDRVVAAGCETPIIPEIMPLTSVRQLERFPQLSNALI
PDDLKDRILAVKDDAAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHEQL
>A0A066PPP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiphilium sp. JA12-A1|TrEMBL
MTAGKYWNCLDDLSLEATTRDLSHLTAIASRFVPGTVIGIPYLANESDADRLHAAATIRR
LGFMPMPHLAARRLPSRDAFARLLTGWAKAKVERLLVLAGDCACPEGPFADALALLETGL
LPSHGIRDVVIAGYPEGHRQIPNPRLARAMRDKLTAIAAQGLAAEITTQFCFSAEHLLAW
LDELRAGGITAPVRLGIPGPANLRILLRYAALCGVGASATVLARYGFSLTRLRSHAAPDQ
LVSALACGVAPVRHGPVFAHFYPFGGMLRLATWLERQRFMHDALVRVGLP
>A0A855NBM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter hyointestinalis subsp. hyointestinalis|TrEMBL
MLKDKIKENKPGILLYGITPPKINLSKDEAYQIAKKQLERLENTGIDGLVIYDLQDESAR
NDEKRTFEFCGTIKPEIYHKEFLKLSYPAVIYKAVGNYTKEEFANFLNTSNNDMLSVFVG
ASSKNDLLKFNLNEAYKLKKEQGGNVTVGGICIPERHEKKGDEDLRVASKIIKGCEFFIT
QAVYNIENAKRFLDDYANLGIKKVPIIFTFTPCGSPKTLEFMRWLGISVSKQFEDRLFES
DDPLSASVGLSLDMFEFLYKYGRAKGVSVGANVESISTRKVEIEASINLLRGIKNIIQNE
KEYNLEELIQSASKFYE
>A0A6L5K9B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTNLEKVLESGRFAVTAEAGPPKGTSAAVMQRKAEMLRHCCDAANVTDNQTAIVRMS
SLAGCVIMKQEGVDPVMQIVCRDRNRIAIQSDVLGAVALGIGNILCLSGDHQMFGNHPTA
KNVFDIDSIQLIQALKAMRDEQKFLCGDDISGEVPLFIGAAANPYADPFEFRVARLAKKV
KAGAEFIQTQAVYDIDKFAKWMEMVVERGLDKQTHILAGVIPIKSAGMARYMRDYVSGVT
VPDGVVTRMEQAQDTKVEGAKVAVEIIEQVKEIPGIHGVHIMAVGWEDIVPEIVKQAGLL
PRPVL
>A0A0M5J5S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila busckii|TrEMBL
MRVTAKLSPATAAAAGAGLRWSSVVAFKRRRPLSCYRWNQLSKRTQSVSSSLAMHALELP
VRQNIGTHASDVPLETCFHYTPSQLQSCPQVESIAQLVANKTKSKKFFFGIEITADNHGK
PTCVDFNQFLPVMPTFISIVWLASYWNVPIAKVQSLQMIQQLQQHIPAMPHFSVYRLTQQ
RLDEFLALNLSNMLAVRGDKVHEDQMYHFGHELVKYARDKRPDLSIGVAGYPMGYTKDQT
ETQEMDRIICYLKAKVDAGADFIITQFCYSPERIVEFLCAARRAGVDKPIMVGVVVPESF
KLYALMETIANISLPEQQRAELELIKQDDEKCRQFFVQLALRTIKAVLEADQGVYGIQFY
TMNRFKSVLEVIGELRKQGVLETPQQDDKF
>A0A523V0W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKLREQVGKRLRERVNTFKEAMLSSDTFCVTWEQVAGRGAFEMQQEKIIENARKAARRQK
VHAVSVTDNPGGNPAISTEILCTEIKKLGIEPLVHLAFRDKNRNQCESLLFGLAALDVRN
ILMLTGDYPSNAGFSGQARPVFDLDSVHGLQLVEMMNRGIEHELAGRRMSLAPTDFFAGT
AVSPFKQSEAELLCQYYKLKKKIDAGARFIITQLGYDARKFHELLLWLKTNGHHIPVLVN
IYVLPFGAAKVMNANQIPGAVVTDKLLVEIAAEAKAEDKGRAARFERAAKLYAIAKGMGF
AGAHIGGHGLTYETLEHIIDTGEELSPRWQEFIAEFDYPQKDGFYFFEKDEKNGLNREPT
APKREKPARPLIVFLSKIAHALIFEPRSPLFKVLKPIARYIDGSHALKRTFTYLEHLVKV
ALFGCMNCGDCALFDVGYLCPMSQCPKNQRNGPCGGSFEGWCEVYPNEKKCVWVKAYQRL
KAMKKEDEIGENLVPPCNWELWETSSWLNFYMDRDHLAMKANIEKNTGTKD
>A0A7C2WGG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAESFRDVLNSGKFVITSEIGPPKGTNLEKTLHHIDLLKDKVDALNVTDNQSSVMRYPSL
GGCILIKERGGEAILQMTCRDRNRLALQADILFAYTRGIRNILCLTGDSIPVGDHKEAKG
VFDLESVQLIRMVRTMESGTDIGGNELNGAIEFYPGAIVTPEANPIEPQLHKFKKKVAAG
AEFFQTQAVYDLGNFRNFMQYARQFNVKILAGIVLLVSARMAKFMNDNVPGIFVPQELID
ELAGVEKGKGLQKGVEIAARMIRTIKDESICDGVHIMAIGKEEIVPEILAIAGL
>A0A8C8EJM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
TPKLQKLFLAVAACDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADTFLKF
VRDCRAIGITCPILPGFVFQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGIE
QAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHPKRKVE
DVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKM
WGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVNRRGVL
TINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHI
VNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQWAKLYE
DESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEQTAEQPN
DEQSDKEQPGK
>A0A6L5B025|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. ZZV12-4809|TrEMBL
MSFLDKLKNEIIIADGAMGTLLYSYGTDSCFEELNLSQSEQIQHIHEAYIGAGADLIQTN
TYAANYLKLQRYGLEDSVKEINGAAARIAKKAAGGRAYVAGTIGGIRGFKPNMITLEEIK
RSFREQLYCLLLEGVDSILLETYYDLEELETVLAIARKETDLPIIAQVSLQEAGVLQNQT
SISDALARLDGIGADVVGINCRLGPHHMLKTLESVPLPKHAYLSAYPNASIPAYTDGKFH
YEGDAEYFRQSAIEFRNQGVRLLGGCCGTTPDHIKAFADVLKGLPPIEEKEIKAVNKVIV
SEKTESSRELPPLQDIVRERPSVIVELDPPRKLDTARFFEGAKALKEAGIDSITLADNSL
ASPRVCNSAIGYLVKQQTGLRPLVHVTCRDRNIIGLQSHLMGLHALGLNDILAVTGDPAR
VGDFPGASSVYDVSSFELINMIKQLNEGLSFSGKDLGQKAAFSVAGAFNPNVRSLEKAVG
RLEKKIEHGADYFISQPVFSEEKLLEVHEAVKDLKAPVYIGLMPLTGSRNAEFLHNEVPG
IKISDSIRNRMASLKDDPAKAGAEGIAIAKSLIDAAAELFNGIYLITPFMRYEMTVELSN
YARETTERLSRRKQHA
>A0A6L5K456|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSLQPLFDKGKFVITAEVGPLKGTDTTELMEAVEILKGKVDAANVTDQQSSVMRLGSLAV
CHLLKMKGLEPVFQVTCRDRNRLALQSDLLSAAVLGIENVLSITGDLPVLGDHPEAKPVY
DLDSVHLLWVMKKLSEGYDMQGNELKGKPSFFPGAVVNPGADTEAARELQLIKMEKKIEA
GARFFQTQAVYDPDAFAKFMKRAGKFGVPILAGIIPLKSAGMAKFMNKNVSGVFVPDELI
EKMTAAEDKTRMGVEIAADLVKELKGMCQGVHIMAIGWEKKVPLVLEAAGI
>A0A6L7MHA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MGDDPLPTFSESLKSGRFVVTAELNPPKGTDLGVLFKHAEALNGMVDAFNLTDSAGANMT
MAPISAAHLMLDRGFETILQVTGRDRNRIALEGELLAASALGINNVLCMSGDPPGRGDHP
DAVGVFDLRAETLLDAVTAMNSGTDMYGNELKGTPTLFPGAVANPGADDLDTELARMEEK
VKRGAAFFQTQAVYDAATFEKFMESARGFGVPVLAGMIVLKSGRMARFLDGNLPGVSVPD
GIIAEMDDARNRAETGVGITARLIRETRDMCDGTHIMAIGWESRIPAILESAGLD
>A0A7C3B3I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
DTEAAFELQLIKMEQKIKAGARFFQTQAIYDAAIFARFMKRAASFGVPILVGIIPLKSAG
MAKYMNKNVAGVSVPEALISRMAETEDKSRTGIEIAAGLVRELKDMCQGVHLMPIGWEKK
VPAILDAAGL
>A0A7C3BU82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MNIAELARQGKFVVTTELGPPKGVDIKEMLENAELMRGKVDALNITDQQSSVMRLGSLPV
CRLLKESNLDPIFQITCRDRNRIALQSDLLGAYTLGITNVLCLTGDSVSLGDHPQAKSVF
DLDSVSLLGAAKQLEEGKDLSGNDLEGAPKFCLGAVVSPESEPLEPQLIKMEKKVKAGAQ
FIQTQAVYDPKKFEEFMKAVAPMNVPIMVGIVLLRSAGMARFMNRYIAGIHVPDELIEEM
EQSEKRAKTSVEIAARLINEMKDLCQGVHIMAIGWEKRVPEVLEAAGL
>A0A6I1Z5M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MARPFRETLKAKDFIVTAEAGPEKGSNIAKLVEHIELLKDRVDGLNVTDNQSAVMRYPSL
GTCLLIKEHGGEPILQITCRDRNRLAIQADLLFAYSRGINNVLCLTGDAIDTGDHKEAKP
VFDLDSVQLIHLVHTLNSGKDMVGNELDGGVDFCIGASATPSADPIEPQLLKFQKKLDAG
MDFIQTQAVYDMDELKRFMENFHKMDNIDGVKILAGIVPIWGAKMAKYMNENVPGIYVPQ
YLIDEIDQAPKGTKAAKGIEMAGRLIRQIKEEKICDGVHIMAIGREERVPAILEAAGI
>A0A7T5K266|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azotobacter chroococcum|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMAVARQLAGYDPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRSLLNTYQDAGIRRIVALRGDLPSGMGMASGELRHASDL
VEFIRAETGEHFHIEVAAYPEMHPQARNFEDDLRHFAAKMQAGANSAITQYFFNADSYFH
FVERARKLGVEQPIVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFG
EQVVTQMCEKLLDGGAPGLHFYTLNQAEPSLAIWNNLGLPR
>A0A7V2P819|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSIVELVKQGKTVVTAEVGPPKGVDVKELLENAELMRGKIDAINVTDQQSSVMRLGSLPV
CRLLVEKDLEPIFQITCRDRNRIALQSDLLGAYVLGIENVLCLTGDHVTLGDHPEAKPVF
DLDSVSLLRAAKELEEGKDLSGNELKDTPSFCLGAVVSPGADPLEPQLIKLEKKVKAGAQ
FIQTQGVFEPEKFEIFMKAVAYLNVPILAGIIPLRSPGAARFMNSNIAGVHVPDSLIDEM
EKAEKRMQKGIEIAARLINDVKSLCQGIHIMAIGMEKRVPEIIEAAGM
>A0A2G9ZWH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium CG23_combo_of_CG06-09_8_20_14_all_52_9|TrEMBL
MKSGSNLEKVLGAGHFAFTGELGPPRGANAEEVRKKAAFLKGNVDSVNITDNQTAMVRMS
SWACCIILIQEGIEPNYQMVCRDRNRLAMQSDILGAYAHGIRNILCLSGDHCKFGDHPQA
KGVFDIDSIQLIATVKKMRDEGKFLSGADLDGVPKMFIGAAANPFADPFEWRVHRLAKKV
AAGVDFIQTQCIYNMNKFREFIKQANDMGLTEKA
>A0A4V2BE12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSHDRPLSFEFFPTKTDAGHEKLMGVARQLAAYKPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVNVPAAPHLSCVGDSKQDLRGLLDQYKAAGIKRIVALRGDLPSGMGMSSGELRHANDL
VEFIRAETGDHFHIEVAAYPEMHPQARNFEDDLVNFARKANAGASSAITQYFFNADSYFY
FVERVQKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLSS
>A0A1E8UHP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria sp. HMSC066H03|TrEMBL
MPVTPPTARAEDRPKLVAAPRAADQSAPAPGGHPAAAATPVAPAAGTTSSEPPAGTSWLV
RRPRRSTLVSFEVFPPRPTADPDTVWRSIDAMAQAGPDFFSVTHGHSGGRGVSREALRHL
RRTTRTPVMAHFTCGGTDRAGLERSVEQLLDDGVRDLLALRGDPPLGAGQWRTPPGGIGR
ASELVRLIRDVERRRFGDGFRPGTRPLSVSVACYPSPARGRDPEADLASLWEKQEAGADY
AITQVLYEPEDYASFLERARSEGIHIPVVAGLMPLTNPKRLQRMTEITGVPVPERLTRFL
TADSPEELRHRGTAATLSLIDDLLDLGCAGFHLYTFNRPDAALTILEHLRVRDAAREYRG
RSPAA
>A0A1M5TPC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis glycolicus DSM 9705|TrEMBL
MKSGSNLERVLAAGQFAVTAECGPPRGADPEKVLKKAEFVKGNVDACNVTDNQTSVVRMS
SLAGCLLVRQSGTEPLLQMVVRDRNRIALQSDLLGASALGVRNLLCLSGDHQKFGDDPQA
KNVFDIDSIQLIHLVKTMRDDGVFPSGEKLDGAPKFFIGCAVNPFADPFEIRVPRFKLKA
DAGADFVQTQCIYNMDTFTRYMEEAKKMGLHERVKILAGVTPLKSVGMAKFMNKMVAGID
IPEPVIKRLADEPKEKQAAKGIEMCIEQIQQLKEMEGIAGVHVMAIEWEEKLNEIIGGAG
LLPRPVVDEGETER
>A0A0M4HNB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp. DG25A|TrEMBL
MKVTDHLLHANGKTLFSFEVLPPKKGENIQSLFTNIEPLLEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFLPDPDGHSYACDLIGQVADLNKGSYLDEEQDDTWATNFCIGAAGY
PEKHFESPNYAADLRYLKHKVDRGADYIVTQMFFDNEQFFAFERRCREAGINVPIIPGLK
PLTAKGQLTMLPRAFYLNIPEELADAVHQAPSNEVAREIGIEWCINQSKELMAHGVPCLH
YYSMGKSDSIRRVASALF
>A0A1M5TPR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis glycolicus DSM 9705|TrEMBL
MEAAAASRSPRPSRLIIELDPPKGTNLQTFLDAALAIRGRVNGIRVTDNEHAIMRMAPLA
PCLALRDKGIEPAMVINGRDRNRLSFQADLLCAAALGVKDIVIKQGHDAREGDQPLARTS
GDLDLDTMLACVARLNGGKDLSGEDLDGATDFTIGVYLELSDDVNRNRQLADYLLKLKDF
GVQSVTLSPTYDLNIIELFLPAAEQTGIRLYPSLLLLKSVTMIRYLNNLAGVPSIPQEFQ
KKMMQAADKKSAGLQVAADFLRELQPLGEAVVLVSLGWKDRLPEFLNLIER
>A0A4R5DUY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter psychrotolerans|TrEMBL
MTKVTEFISQANGKTLFSIEIIPPVKGQNINELFDSIEPLMEYKPPFIDVTYHREELIDR
VGTNGLIERIPVRKRPGTVGICARLMERFHVDAVPHVICGGFTREETEDVLFDLHYLGID
NVLVLRGDPEKSAGVFQAKKGGHTYASELVTQVHNMNNGILLNAETETAPTNFCIGVAGY
PEKHFDATSFDTDYEHLRRKVELGANYIVTQMFFDNQKYFSFVERCRAEGITVPIIPGLK
PLATKKQLSVLASIFHLEFPEDLVKAAMQCASDKDVRQVGIEWGVQQCRELLAYGVPVLH
FYTMGKSDNVAQIAKQVF
>A0A3A4VMD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSLREHLAAGKFAVTCEVGPLKGTDTGEIKEIAHLLKGKVTAANVTDQQSSVLRLGSLVV
CHLLKDEGLEPIFQMTCRDRNRLALQSDLLGAWVLGLENVLALTGDLPVLGDHPGAKPVY
DLDSVQLLGAIKRLNEGFDLSGNELKGKTDFFAGAVVNPGADTEAAFEMQLIKMEKKIEA
GAKVFQTQGIYDLDAFARFIKRVEQYKVPVMAGIIPLKSAGMAKFMNKNVAGVFVPDPMI
EKMTAAKDKTQMGIDIAIELIKGLKDLCQGVHIMAIGWEKKVPQIVEAAGLSGVAT
>A0A2D6IQB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MLELSVEFFPPRTGEGISRFNKAADDLVPLGFGFASVTYGAGGSTREGTLTAARELKKRF
KEGVPHVSCYGSDEESIYELLKTYSNDGFSRLVILRGDLPSGYGGLGEFKNAVDLVRFVR
REFGDQFKIEVAAYPEKHPQSHSFEQDIDYFVEKVNAGADGAITQYFYNSDAYFSFVDEV
QSRGVSVPIVPGVMPITNFSQLARFSDSCGSEIPKWIRHRLSDFGDDRVKIYNFGITVVT
RLCKDLIKAGCPGLHFYSMNQSRPIIDILSGIDFATDG
>A0A2D9M006|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MLRDRASLNPFRLRRPRIVSATSVSRRSAGVVKILSTWRXXGFYPIPVATTXDMLXFLYL
RRRSASKFMRRLMKISXILKNKRTLSFEFFPPRDQQGVEQLFETIDHLKRYEPDFIDITY
GAGGSTQRLTXELCVRAYRDSGVTVMGHLTCSAQTKEMVHSVLERFESEGIENVILLRGD
PPQGEDXFVPAEDGFSHATDLIQHAKENFDFGIAAACYPEAHPESLDADSDLYYTKMKVE
QGAEFLITQLFYDNEDYYAFVDRARQSGIDVPIIPGLMPILNASQIRRITSLCGATIPXX
LDRQLERHADDNRAVRQIGINHTLRQAQELMASDXPGIHFYVLNRRFSITKILDNLXGPX
VGVTSS
>A0A523QNA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTRLERILASGKFAVTAEAGPPKGTSAEVIRKKGELLRRCCDAVNVTDNQTAIVRMS
SLAGCLLLRQQGIEPVMQMVVRDRNRLALQGDVLGAVALGINNILCLSGDHQKFGNHPTA
KGVFDIDSIQLIQTLKMLRDEKKFISGEDVSGEVPVFIGAVANPFADPFEYRVSRLAKKV
KAGADFIQTQAVYDVPKFARWMEMLTERGLDKKVHILAGVIPVRSAGMARYMRDYVPGVT
VPDEIVTRMEKADNPKEEGVRIVLEIIEQLKDMPGVHGIHIMAVNWEDIVPEIVQKSGLM
PRPVV
>A0A523P2Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MQKAQEQKTFSFELFPARSAEARGKLELTCKRLSALKPDYFSVTFGAGGSTRELTLETVL
AVAEATGVDSAPHLSCIGYPLEKIRAVLQGYLAQGIRRVVALRGDMPSGTTGVGELRYAN
ELVEFIRSETGSAFHIEVAAYPEFHPQSNSATADLNNFKRKVEAGADSAITQYFYNPDAY
FRFLDSCHKLDIDIPIVPGIMPIINYTQLSRFSEMCGAEIPRWIVSRLRDFGDDRIAIRA
FGIDVTTELCRRLLDQGVPGLHFYTMNQYEASEAIWQNLGIETSHSESRRGETAEN
>A0A388THF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Termititenax persephonae|TrEMBL
MRLAEIYRPAKTSISFEVFPPKTDEGFAPLLAELRQLKEFQPGLISVTYGAGGTTQGRSL
KLLGAIVQELGLELMAHLTCIGSSENSILNFLQKISAWGVQNILALRGDFPKNNPDYQPE
SAAFQHAADLVRFAKQQTKMSVAAAGFPEKHPEAASLADDLRHLREKVRAGAEAVFTQLF
FDNQYYYAYVAAARQAGITVPIIPGIWTITSLKQVQKTAELSQAKIPADLLAHLEKASAA
EVRRCGITYAAAQIKDLLAHNAPGIHLYTLNQAEAVTEVLRKVL
>A0A2W4M6T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSIEYLQERIAAARERLRCRPSVSFEFFPPKDDAMARTLWQSLERLAPLEPRFVSVTYGA
DGSTRTRTREIVMRIGQVLPLTAVPHLTCVGASRAEILEIARDYWSRGIRHIVALRGDPP
QGTGAYTPRPDGFAFAVDLVRGLKSVADFEISVAAYPETHPEAPSAMADLDHLKAKLDAG
ATRAITQFFFEPETFLRFRDRCAAAGIEAPLVPGILPITRFPQMLRMAERCGTQVPSWLI
NRFEGLDDDPETRRLIAAAVAIEQVQALERHGVRAFHFYTLNRAELTYAICHALGVRPHA
TSRAAV
>A0A1M3C015|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium 66-5|TrEMBL
MAVPVSFEFFPPKTPEGVGKLRVVREQLYRLQPEFCSVTYGAGGSTQAGTFAAVQEILAE
GVPAASHFSCIGATREKVREQLAELRAMGVNRLVALRGDLPSGYGMGGAFQYASDLVAFI
REETGRHFHIEVAAYPETHPQARSPEADLKAFAAKVHAGADAAITQYFFNADAYFRFVDE
ARRAGLDVPIVPGIMPILGSTQLLRFSDACGAEVPRWLRLRLQGFGDDVASIRAFGLDVV
ARLCEQLVAGGVPALHFYTMNQSAATLELCHRLGVGPA
>A0A523ZKN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAVSNLERVLESGAFTVTGELGPPQSADPEVIREKARLLKGYVDAVNVTDGQTAIVRMA
SWAACLIGMSEGLEPTVQMTCRDRNRIALQMDILGMSALGMKNLLCLTGDHQSFGNHPQA
KGVFDIDGIQLLQIARNMRDEKKFQSGDEISVSPSLFIGAAANPFADPFDFRAIRLAKKV
AAGADFIQTQIIYNVERFARWMEAVRQRGLHKKVYILAGVAPIKSAGAARYMKTRVPGMD
VPDEVVDRMASAPKGEAKRVGIDLCVDIINQVRQIEGVAGIHLMAIEWEEAVAEIVEKAG
LLPRPQLSA
>A0A3A8F840|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter rongchengensis|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKIVHQELQLLNPEFFSVTYGAGGSTRERTLAAIADFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQAENFDADIKHFAEKVKAGANAAITQFFFNPDAYFYFV
DRIQKQGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHTEPNRQLILDLGLA
>A0A369W359|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas aracearum|TrEMBL
MTISVSQLAEAQRALASPLFADVGGDARISFEFFPPKTEKMEEALWETVRTLEPLGPRFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATREEIDAVADEYWAAGVRHIVA
LRGDAPDQKAGYAPHPGGYENAAALVEGLRRRHPFEISVAAYPECHPDSADSAGDLDNLK
RKMDAGATRAITQFFFEPETFFRFRDAVAAAGMDVEIVPGIMPVSNFASVKRMSAMCGTD
VPAWMGRLFEGLDDHPAARQLVAATLAAELSRRLYAGGVRDFHFYTLNRAELSYAICHLL
GIRPQPASKEQAA
>A0A7W8NK02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. K2C7|TrEMBL
MADHNFSIEFFPPKTPEGTEKLRATRAKLSELHPKYYSVTFGAGGSTQQGTLDTVRDILA
DGEEAAPHLSCVGGTRESIRKVLADFKDAGVQRIVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDHFHIEVAGYPEMHPQARSPQDDLQALVRKVQAGADSVITQYFYNADAYFQFIE
QTQKVGINVPIVAGIMPITNYTQLLRFSEMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTALCERLLEGGAPGLHFYSLNQAAATTALWQRLVK
>A0A7K6B689|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Upupa epops|TrEMBL
MVNETQHTSSASCSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITMHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEELEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIITALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7K7BB90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothoprocta ornata|TrEMBL
MVNENQHTCSASSSSKSDGGSSSGSESSKESSRCSTPVLDAERHERLREKMRRRQDSGDK
WFSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPAGEEWQEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAENYEADQRHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATIEVLKRLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWSSRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKALKKYETRVNY
HIVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>C4RLK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. (strain ATCC 39149 / NRRL 15099 / SCC 1413)|TrEMBL
MALGLPSVLPNPQPSIGELIRDRQPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVR
GDPPGDPGGEWVRHPEGVLYAEDLVRLVRDCGDFSIGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAEGCDTPILAGVMPVTQLTTIERSVQLSGAPF
PPALAARFAEVADDPEAVRRLGIEQAAEMCRRLLDEGVPGIHFITLNRSTATREVWQQLE
VSARV
>A0A5M8SH85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium AB60|TrEMBL
MDSPFRFSFELFPPRTPEAAARLPHVLTQLAAARPEYFSVTHGAGGSDQDGTYETLLTVV
NQTGIPVAPHLTCIGSTREKIAALLEKYRAAGVRRIVALRGDLPATAYTSAAPGEFRYAN
ELVCFIREQHGDWFHIEVAAYPEMHPQAANPGADFDNFRRKVDCGADGAITQLFYNAASY
FDFMERCARANITIPITPGIMPITGLANIVRFCSGCGADLPRWIKLRLEELQDDKPALQD
FGLSVVTRLCETLLKGGAPGLHFYTINQADPTLRIWANLALTPSAAA
>F7P0M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rheinheimera sp. A13L|TrEMBL
MSFVSAQYLESINRNLQDVAGKVNVSFEFFPPKTEQMENTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASRAELERIAKDYWDNGIRHIVALRGD
LPPGNKEKPALYAADLVEILRSVADFDISVAAYPEVHPESPNAQFDLLNLKRKIDAGASR
AITQFFFEPEKYLRYRDRCAAIGIDVEIVPGILPVTNFQQLTKFATMTNVAIPGWMNKAY
EGLDQDATTRNLVAANIAMDMVKVLSREGVNHFHFYTLNRCELSYAICHLLGVRPQSAIA
>A0A650EP91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Firmicutes bacterium|TrEMBL
MRIADKYKQGRPVLSFEIFPPKKDDDMDALTPVLAALAAQNPDFVSVTCGAGGTGGRNKT
ITVASMLKKDHGIEPMAHLTCITSDKAEIANSLAEAEAAGVSNILALRGDIPDGYDIAGA
QYRYAKDLVADIKAQSGVCIAAAAYPEGHIDCADDTLSMEHLKQKQDAGAEFFVTQLCFD
NEYILRFRESAVKAGITAPISVGIMPMMSKAQISRMIFMCGASLPSKMIKLLHQYENDAD
GLLKAGMEYAGDQIEGLIRAGVDGVHMYSMNKPQIAEYGMSRARAAL
>A0A087NN87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pyrrocinia|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDREAIRAFGADV
VTDLCRRLIDAGVPGLHFYTLNAATATRTICERLAV
>A0A3M3KQU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. zizaniae|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDGKDDLRSLLAQYREAGIKRIVALRGDLPSGMGMASGELRHANDL
VTFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A255SU83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella bryantii|TrEMBL
MNISEILNSSNAQKHFSFEVLPPLKGNGTDGLFRTIDKLKEFNPLFINITNHSFEYIYQE
LENGLIEKSRIHRRPGSVAIAAAIQNKYNIPVIPHLICSGATKEDIEYELLDIQFLGIET
LFLLRGDKAHEDNRFKAVPGGYDHATELIKQVNQFNNGYFVDGTPIKHPGKKFEYGVACY
PEKHNEAPNLDIDLKYLKEKQDLGATYAVTQLFYDNKKYFDFVKKAREMGITIPIIPGIK
PFAKLSQLSVVPSVFHIDFPEELANEAMKCKNDEEAKQLGIEWTTHQVKELYTNGVNDVH
FYTVSAVDSVKEVARRLL
>A0A1T4M883|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Garciella nitratireducens DSM 15102|TrEMBL
MSIKKIFQQKKPVISFEIFPPKKDADVATVYKSIDQLVSLKPDFISVTYGAAGSKDNKTI
EIASFIKNYYQIESLPHMTCITADKNRISENIYQLKKNHIDNVLALRGDIPKDFIAQKHN
PYHHAIDLIREFRKKGDFSIGAAAYPEGHMECESEEKDLQYLREKVDAGVDFLITQLFFD
NDSFYRFLDQMEKKQIDCKVSAGIMPILSKSQIEKMIFMCGASLPAKVVKLLTKYEYQPE
ELRKHAIEYAAWQVEDLLSHGADGVHIYTMNHPEVAKGILNRIR
>A0A6N2XT10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster bolteae|TrEMBL
MNTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTRDDVLLILEQLKEQKIENILALRGDRTADREPAGDF
RYAADLVEFIKNHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFRERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFISMMERYGDNPIAM
RDAGIAYAVDQIVDLAAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>A0A7W5HIF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas stenophila|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGRFALTTEIDPPDSADPAEVLRRAAIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYATILQMSCRDRNRIAMQGEILGAAAMGAC
NLLCLTGDGVQAGDHPQARPVFDLDSMSLLEVARRMRDEGRFESGRAITDPPRIFLGAAE
NPFVPPQSWRARRLAKKVAAGARFIQTQYCFDPPRLRDFMAEIADLGVLEGPDRAFVLVG
MGPLASARSARWIREHVPGVHIPDAVIRRLEGARDQRAEGERLCCDILAEVREIEGVSGA
HIMAYRQEHTVARIIEETGVLEGRVPWYPGRDNPAELNPEAPEADVDAVASG
>A0A7C7DRR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceticus sp|TrEMBL
MKEINNLKVGSNLEKVLASGQFACTGEIGPVTYASFANIDKHAEEMRGKVDAVNFTDNQT
AVVRLSSWAASLRLIQLGMEPILQMVCRDRNRLAMQSDFLGAYAHGIRNVLCLTGDHQAF
GNHPGCKGVFDVDSVQLVRMLRRLRDDGCFECGAECKEPPKFFIGCAENPFGDPFEFRPI
RLEKKIEAGADFVQTQCILDMERFERFMEMCVERGLHERAYICAGIMPVKSPRMARYMQT
SVPGMIVSEEFCQRLEKAEDPKAEAVEISVEYIKRCKEIKGVSGVHVMAVAWESIVPTVV
EKAGLLPRPTF
>A0A2S5G7E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jeotgalibacillus proteolyticus|TrEMBL
MNLREELRDRILIADGAMGTLLYSYGTDQCFEELNVSQAEHIQKIHSAYIEAGANVIQTN
TYGGNYLKLERYGLQDHVKEINSAAVRNAKLAADAADKGTHILGTIGGIRSIRPQSIELE
EIKRTFREQLYCLLLEGVDGLLLETYYDLEELSTVVDIARQATDLPIIAQVSLQEIGVLQ
DGTPVANALKQLEELGADGVGINCRQGPFHMLRSLESVPLPKHAFLSSYPNASLPSYAEG
SLQYNNNAEYFGECARSFQAQGVRLLGGCCGTTPDHIRAFSEALEGAAPITEKKVETPEP
KIEVKSKSLDLPEPLSSIVSRRPSVIVELDPPKKLNTDAFMKGAKVLTEAGADAITLADN
SLASPRVSNESLGHLIKQESGARPLVHITCRDRNLIGLQSHLMGLHTLGLHDLLAVTGDP
TKVGDFPGATSVYDVSSFELIEMISQLNNGVSMSGKDLGEKTSFSIGAAFNPHVRSVERA
VLRMEKKIAAGADYFMSQPVFSQEKLLEVYEHTKHIEKPLYIGLMPLTGSRNAEFLHHEV
PGIKLSDEVRERMAKVSDDKEKSAKEGIAITKSLIDAALEMFNGIYLITPFMRYEVTAEL
TRYANEQAAKRAGGITNVSNIIQ
>A0A1W6ZKT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodoplanes sinuspersici|TrEMBL
MMKAIAPRASRLMNGRGQKLRVSFEFFPPKTEEMERSLWEAIERLAPISPHFVSVTYGAG
GSTRERTHATVKRMLDETALTPAAHLTCVDATRDDVDAVVQNYREIGVRHIVALRGDPTS
GVGAHYAPHPGGYQNAADLVAGIRRIGDFEVSVSAYPEKHPDSRDTEVDLDMLKAKVDAG
ATRAITQFFFDNDLYFSYLDRVRARGINIPIVPGIVPVQNFKQVRNFAERCGTSIPRWLA
QRFDGLDDDVATRKLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAVCHLLGLRPAL
KEAA
>A0A2E7GLF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium|TrEMBL
MSETQSYTTIENITSLMSGFTVEITPKGAEKIEDFRHHLATGTKVYVTALPDTDFADTVK
TCVKLAEQGMQAIPHITARSIDSKGELESRIKRITEEAGVTQVLAIAGADKIASGPFEDS
ASMLETGFFDKYGIKSIGIAGHPEGSPDIAHPMLREYGRRKIDYAQVTDIQLYLVTQFVF
QAEPIINWLERIRSENNQLPLVIGIPGIASLKSLIGHAKACGIGPSMTVLTKQAKNIHKL
LTLQEPNELIRQLADYSATHPQSNIAGLHIFPLGGLLPSAKWAYKVAEGQIELTKHAFKT
VY
>A0A139CXR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium sp. T82-1|TrEMBL
MKIKNIFEEKEVVFSLEVFPPRPDVPIENIYQTLEELKDIDPDYISVTYGAGGGVKKNRT
CELSSIIKEKYDVEALAHLTCINSDQETLNKILARLESKNIENILALRGDKPVDGEALGD
YNYAYQLVEHINKHNDFGVAAACYPEGHLETESLDQDLEYLKQKVDRGVDYLISQMFFDN
SLFYKFRNKAEKKGINVPIEAGIMPVINKKQVGRIIELSDAYFPKKFQKILDKYEDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKA
>A0A1S1TBK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. LCM 4579|TrEMBL
MERTTLHPSERGEISLSFEYFPPKNEEMEAQLFQTVADLSAFVPAFQTVTYGAGGTTKAR
SLTAVRRMIGEMGLRNTAAHLTCVGAPRPEVDSVIEEFVACGVRHFVALRGDPQGGVGSA
YQPFPGGYENAAALVKALRARGDFEISVSAYPEKHPESRDAAADIDMLKRKVDNGATRAI
TQFFFDNDDFERYVDQVRRAGIEVPVVPGILPINNLSQVMKFAGLCGSTVPDAITSRLAH
LDDQPEERFREASHIAAEQIVDLVRRGVRDFHIYTMNRSPLVIAVCELLGYARSQVNAQE
MAVGSIKTAAGAR
>A0A0V1CXV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella britovi|TrEMBL
MPALLMPSVPKGMSNIFVFTYGLLYNMNSTYNLQVKLKSPAYQRAVTVAKVGNPSQQTDF
GVYFEEDSFLSLMASLEAVELKATRHDLNSAAKKSTDEIYRPLIDRIKENISSGRRFFSL
EFFPPHTTEGLINLLKRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCILNFCLL
DTMLHITSVQYDEKTVLFNLERAKKIGIRNILALRGDISDDANVTTTDFQYACQLVRFIR
SHYGDYFTICVADAGADFIITQLFFNEMHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIM
KIVQLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRKLLNREHHVVPGLHFYTLN
QEKSILEQIGFWKKVPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYLCRTRDWKQFPH
SRWGDVGNPAFGDLKHYLFSSIDQMDDSCALDMWDKELSTLEHVRDIFCNFIARTPNRHG
HSVRRLPWNENHLDPAADVLKNELIYYNSNGILTINCQAAVNGLPSSDPIFGWGEANGYI
YQKGYLEFFASSTCTTILLNHVQNFPSINYHAINFDGSFETFNYDEDATVALTWGVFVGQ
EIVQPTVANAASFRVWKDEAFDLWQRWAGLYESGSIGRKLLQRIHDDYRLITLIDNDYPQ
PCSLSALLRAVISDYIGGKNLTTDDDRLAYFDWQCVRECVRACAYVENSGRLALRASKHG
ITAEKEEEEEEAIIE
>A0A1Q7UZI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium 13_1_20CM_3_54_17|TrEMBL
MHITDIMRGDSPTFSFEFFPPKTAQAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
GLVERIQHTTKLDPIPHLTCVCHNEEEIEAILLRYAKSAIGNVLALGGDRPVGIAYDKAR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLLEMDHFKAKVDAGA
NYIVTQLFFDNRDFLDFRERCALVDINIPIIAGIMPITTLNGFKRIAELAGGARFPARLL
RALQRCQNDPEMVRRVGLHFAIEQCHDLLDNDVAGIHFYTLNRSDATRMIFDSLGIPRRR
NAEPSSV
>A0A178Y5A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer glycinis|TrEMBL
MSPDINPLDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYSPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIVTRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRRPWKREATPAETLVAERLDHLREGIEENQQQMAEAAAH
HPH
>A0A2K8W6X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sagittula sp. P11|TrEMBL
MTRPEISLEFFPPKNIEGTFRLWDSVQVLAPLKPRFVSVTYGAGGTTRDLTRDVVATIHK
HSGLRTAAHLTCVNATKEETLQVARDFAKVGVNDIVALRGDPPKGSAGFEPHPEGFANSV
ELIEALAAEGDFTIRVGAYPDIHPEAASGQADIDWLKRKLDAGASEALTQFFFEADTFFR
FRDACAKAGIDKYVTPGILPIENWKGARRFAESCGTKIPEWVIDAFEKAERDNRTDLLAT
AICTELCDDLIRGGVDKLHFYTLNRPELTRDVCFALGVTPDIKLEEVA
>A0A0F5VM18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WM6386|TrEMBL
MTTLRDILDGGTPSFSFEFFPPKTAKGERTLWEAIRRIEPLAPSFVSATYGAGGSSRDRT
VEVTKRIATDTTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGDPNAPWI
PHPAGFTHADELVRLVKESGEFSVGVAAFPERHPRSADWDSEIRHFVAKCRAGADYAVTQ
MFFDVEDYLRLRDRVVAAGCDPPIIPEIMPATDVRQIPRFAELSGAAFPEDLAHRLDAVR
DNPADGHRIGVEYATAMAERLLAEGAPGLHYITLNRSTATLEIHRNVTNSRSAQHALAAQ
R
>A0A2R3QLN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mendocina|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTVNTVLQLD
GDVKVPTAPHLSCVGDSKVELRELLNLYRNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGEHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGANSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIDSIQAFG
EQVISEMCERLLAGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A6L4B917|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zoogloea sp|TrEMBL
MSTKPPISIEFFPPQTSEGVEKLRATRARLAELKPEFFSVTFGAGGSTQARTFETVFETQ
REGYEAAPHLSCIGSTREHVREILKRYQDAGIHRIVALRGDLPSGVGDPGELRYANELVE
FIRAETGNHFHIEVAAYPEYHPQARSPKDDLLAFKRKVEAGANSAITQYFYNLDAYLHFR
DECAALGVNVPIVPGIMPIVSFSKLARFSDACGAEIPRWMRRKFESFGDDSESIKAFGLD
VVGELCARLIEAGAPGLHFYSMNQAGPTLALCERLGLQG
>A0A845C8Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineaceae bacterium SB0666_bin_21|TrEMBL
MVPFLEALQAGPLLADGGMGTLLLAHGARVDQNLEELCLTEPDRVRELQLAYARAGADIL
LTHTFGAQSLRLAEHGLDSQVVAINRAAARIARDVRESSGRDIFIAGDIGPLGRALAPRG
PISTEQARTAFREQAAALLEGGVDLFCVETMTDVAELRQAVLAIRELSDLPVLASLTFSA
DGETLFGLDAAAAAEMLTDLPIDVLGANCAVGPTALLDVLATLRAARPGIWLSAIPNAGL
PTRVDGRFQYEAGPEYFAAMVPEFLARGARIVGGCCGTTPAHIRAMRQALDSIESDHEGD
SVHLETEPSVEWGVRVSETGGPHASDPVSASGLLAKMRAGEFVVSVEVDPPRGLNPERQL
AGARLAKERGADAINVADSPMARVRMGALALSTLIENRVGIETILHFTTRDRSLMGLQAD
LLGAHALGLRNILALTGDPPSLGESQNSSPVYDTDSVGLVQILQQFNRGQDLQGKEMGQH
SSFAIAVACDPTRPDLELETERLTRKLQHGADFIMTQPIYDPMVWIRFADLYASRYGPIP
APVLIGILPLQSFRHASFLHHEVPGITLTPTALNSMKEAGKQGRQAGVVMAQDLLLDLID
APHVQGVYLMPSFGRYETACRVLDVLDRTPVREVA
>A0A2A4YYP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|OCS116 cluster bacterium|TrEMBL
MNDKLNISFEFFPPATEKMEETLWKSVKRLETLKPRFVSVTYGAGGSTRERTHKIVTRLA
HTTSMIPAAHLTCVDASRDEIDEIIQNYWDEGVRHIVALRGDPKAGIGEKYIPREDGYAN
AEALVKGIKKIGDFEISVAAYPEQHPESGSLQADLDNLKAKIDAGATQAITQMFFDNEQF
YRFLDECEKAGINVPIIPGIAPVINFKGTVNFAKKCGTSVPRWLHRRFDGLDDDEGTRRM
VAAAVVVEQVRDLYAYGVRDYHIYTMNRAELTYTIAHQLKNIA
>A0A2D7IU31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ponticaulis sp|TrEMBL
MSLQHAPKNIHVSFEFFPPKTEKAEDKLWESVRRLEPVHPEFVSVTYGAGGSTRDRTHRT
VKRMVEETNLVPAAHLTCVSASKAEVMGVVDDYLDAGVQHIVALRGDPPEGMGAKFEAHP
EGFSGSIELIEAIRNYKPALGKRFEISVAAYPEAHPDSHGLKRDLEILKAKQDAGADRAI
TQFFFEPDHYLSFLDAARDAGIHIPIVPGIMLQPNFNGLKRISALCGATLPNWLHELYEG
LDDDAEQRELITANVAADLTMKLADKGVKDFHFYTLNKAGLSLSTCRLLGIKPTAKAA
>H0H279|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae x Saccharomyces kudriavzevii (strain VIN7)|TrEMBL
MSIRDLYHERASPFISLEFFPPKTDLGTRNLMERMHRMSALDPLFITVTWGAGGTTAEKT
LALASLAQQTLSIPVCMHLTCTNTDKTIIDDALDRCYAAGVRNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQRHGDKFCVGVAAYPEGHCEGEAEGNEQDPSKDLVYLKEKVV
AGADFVITQLFYDVEKFLTFETLFREQISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
SILNRFPPEIQSDDNAVKSIGVDILIELVQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SFVLSHIVNESSEEEGEDETGGEIRSIENVPIEDADGDIVLDDSNEDTAANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKNRALELWGTPRTIGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWEA
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSQVKQTTIIEEESFKA
WRDEAFSIWSEWAKLFSRNTPANILLRQVHRDYCLVSIVHHDFKETDELWEMLLD
>A0A178B169|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stagonospora sp. SRC1lsM3a|TrEMBL
MHISQKLAQARAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQTVYGLETCMHLTCTDMERSKLDEALRDAYQSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVKYIKDKYGNHFDIGVAGYSEGSDDNDDVDELIDHLKEKVDAGATF
IVTQMFYDTDIFLDWVNRVRAKGVDVPIIPGIMPIHTHAAFLRRAQWTRCNIPQHWTDAL
EPVKNDDVEVREVGKGLVAEMCRKLIDAGITHLHFYTMNLAQATRMVLEELELLPDVGSP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPTSIKDLSDLFVRYMEGKLESLPWSEQPITGEATSIQKDLIE
LNRRGFLTINSQPAVNGAKSSDKVFGWGPRNGYVYQKAYLEVLVSPEYIAEIITRIERDP
EFTYYAVNQDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHASVSPSRYVIQDVVDTWYLLNIVHNDFHAERGIFPIFDGLEVKDMDKPLHSANVDL
PTADDSGAANGTRGANGTNGATKEAHGEEKQDHGLLATAKAAAVEVTNGIKSLAVSN
>A0A1B9GGQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kwoniella bestiolae CBS 10118|TrEMBL
MPKLNSLLAGRIAPFHTFEFFPPRTEAGLVNLLDRIQRLASAPLPSPLAVSVTWGAGGST
ADKSLELAEHITKLGLEVILHLTCTNMPKDKVDQALEKCKSLNIRNILALRGDAPRSEEY
ATEPNPQPDYFQHADDLVRYIRNNYDDFFCIGVAGYPTPHPDSESPESDLEYLKVKCDAG
ADFIVTQLFYDVQGFLDWVKVCREKGITQPIIPGIMPIQNFSSFRRLVNLTKCPVPESIS
SDLLPISSDDSSVKKYGAELATKMVSQILESGLVPGIHFCTLNLEKSVRTILENLNWTST
SSASLAVNGNSNIERSPIIRHNRLIEDDQPLTNGAIAINGHSTSNQNNRSQITGLSVSPS
EASQIAQWGLQHHSLPPVPKKAAIQGGAPSNSGQGQEDSWDEYPNGRFTDVRSPAYGEID
GWGSGLKITAAQALKEWGTPTTLHELSSFFTSYLKSSPQTPTTPFCDLPLSPESLTILPH
LLELNSEKMNCWTVGSQPAVDAVNSEDPVHGWGPRGGYVFQKSFVEFFVKPEEVGKLREK
VEKRGGGRISFYAGNKKGDFETNTEEDSVNAVTWGVFPGQEIVQSTIIETESFLAWKEEA
FDIWTEWSLLYPRLSPARKLLEGIASEWWLVSLIHHDYKDKEGLWRFLLEQ
>A0A2A2PUH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas moraviensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETADHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A2W0EMP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas jessenii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1V6PR02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium antarcticum|TrEMBL
MHIREKLAKNEADGKTGVSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPIEKVDQALQAAYKAGCTNILALRGDPPRDKEV
WEAADNGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNSDVEQLIDHLKEKVDAGSTF
IVTQMFYDVENFIDWVKRCRAKGIHVPIIPGIMPIQTYAAFIRRSNWTKIHIPPTWMEAL
EPVKNDDSVVREIGKSLIAEMCRKLMAAGINHLHFYTMNLAQATKAVLDELGLCPSEEAP
IQRALPWRPSLALNRRGEDVRPVFWRNRNSSYVARTQTWDEFPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDLSNIFVSFLKGKLDRLPWSDSPITTEANDIQDNLLD
LNQRGFLTINSQPAVNGIKSSHSVYGWGPKNGFVYQKAYLELLVPSYLIDELITRIEKND
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCYNAASASRKLIENVMEDWYLVNIVDNDFHRSNAVFELFKDLAVKDLEVPVEVEAPAKP
ETNGTAVPNGVAAN
>A0A1G7ZT90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentzea fradiae|TrEMBL
MTTVVERLQGESPKFSVEFLPPRDAEDEKVLWKAVRELEGLDPAFVSITYGAGGSRRDRT
IRATGRIAQETTLLPVAHLTAVDHSVAELRNVIGWYAAIGVRNVLALRGDPPGDPMGEWV
AHPEGLNYADELVALVRELGDFCVGVAAFPYGHPRSPDLDTDLKFLLRKLNAGADYAVAQ
LFHAPEPFLRLRDRVAAAGCSAAILPGIMPMLSPRGLAKIVELSGADLPVEISRRLEPYA
DDVASFRAEGIDIATEMCQRLLDEGVPALHFYTMNRAKATREVLSRLGLVTRA
>D1NSG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium gallicum DSM 20093 = LMG 11596|TrEMBL
MHTRFDYEKRNQHETRPHFTLEVFPPKRNASVGTIYDTLDGLTGLKPDFISVTYGTGLSA
DRTATARIAHTIHHEYGINAVAHLTAQYLTADDVDEALAMFDDAHVSGILALRGDRNPDR
EPVNVFTHASDLTAYIRQRRPDLEILGACYPEKHPQASTLQEDVDNLKRKVDAGATRLIS
QLFYDNDDYYRFLDLARDAGITVPIEAGIMPVTNAKSVRRMTSMCASRVPAPVEQMLTRW
SDDPATLQQAGIIYASQQIADLVAHGVDGIHLYTMNRPAVARRIWTNVQDLFTADQQPQA
>A0A0Q6W967|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Root1220|TrEMBL
MAPNSDARRKIGISFEFFPPKSEEMEGQLWHAVSELQDWNPDFVSVTYGAGGTTKAPTLA
TVSRFLANTPLATASHLTCVGATKDETHSVIDSFRQAGVKHFVALRGDAPAGVGAPYQPH
PGGYANAAALVAGLREIGDFEISVSAYPEKHPESRDSAADIDMLKQKADNGADRALTQFF
FDNDNFERYLEKVRAAGISIPIVPGIMPILNLTQLKRFAGACGTVIPGFLDERFSGYDDK
PEERAKVAAEVAAEQIEDLARRGLADFHLYTMNRAPLVSAVLTNLGFKREVGKNLGTGAA
A
>A0A238YY32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibacter flavus|TrEMBL
MKVTEHIKQANGKTLFSFEIVPPQKGQNIQDLYNNVDPLMEFKPPFIDVTTSREEYVYIK
KDNGLLEQKMTRMRPGTVGICAALKYKYNVDAIPHVLCGGFTKEETEYVLVDCHYLGLDN
LMALRGDSMKHESFFIPTPGGNNYASELVTQIKELNEGKYLHNIIETNNKSDFCIGVAGY
PEKHLEAPSMETDLRRLREKVDAGADYVVTQMFFDNQKYFDFVDKARNIGITVPIIPGIK
PVAVKRHQQILPQVFRLDMPEDLIAGIEGCKDNKQVRQVGIEWAIEQSKELISKGAPVVH
FYSMGKSDNIKAIAKEIF
>A0A1I3DE53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. Gha|TrEMBL
MTDLTNPAAADGHLAVKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAGG
STRERTHSTISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAGG
IGTPYASHPDGYQTSDALVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKAKVDAG
ATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRNGTSVPEWLA
AKFEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVVAICHLLGIRAKS
AQKAA
>A0A6N8TBI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella zoogloeoides|TrEMBL
MNPATASPARKDIRLSFEFFPPKSAEAEGQLWETAAELSAYRPGFMSVTYGAGGSTKAPT
LATVRHLLDMGLPAASHLTCVGATKEEVHAVVAEFQAVGVKHFVALRGDPPGGVGAAYQP
HPGGYANAAELVAGLRTLADFELSVSAYPEKHPQSPDVAADIDMLKRKVDAGATRALTQF
FFENDDYERYLERVRKAGIAIPVVPGILPVHNLSQVQKFAGLCGASVPGWLAERLAPFDD
RPQERAAVAVELAVRQVEDLIARGVGEFHFYTMNRATLVSAVCDGVGFAKIAPNHTAGAA
A
>A0A7Y0TVH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobiluncus mulieris|TrEMBL
MASGVDWVAPDAGGVLDTPGAPVAFTSVSRGANPKSSRNPTRPVRVSFELYPPRNPDPFS
QAWAGIDRLLDAHPDYVSVTFGTSNSTSASSQSVLAHALQRLGRPVLAHLTCVGKTRAEL
STTITEMLDIGVRDFLALRGDNPKGSVNWEPAPGEFSRASQLVTLLREVAAEYLGDARAI
SIAVAAYPAGTVSARTNAVAALAEKQSAGADFAITQVFYNADDYGALLDSATYQGVSIPI
IPGIIPFTDAARLQRLEGLTGVSVPSRLQAISEISDPEERFLEGLSATLDFVNDLIQAGA
PGLHFYTFNRPRPVLDLVEHLRSRGFTHVDEDFSSELLDLMNAAMQRFSP
>A0A5F8GXA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monodelphis domestica|TrEMBL
MSHHRGRAPPLGHCCQPLGMGSQETGSLRLSVPSSISCRNPAMVNEARGSCSEGSSSGSE
GSKDSSRCPTPILDAERHERLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRFDRMG
AGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVDYCGLETVLHMTCSQQNRDEITSHLHK
AKRLGLKNILALRGDPIGDEWEEEENCFSHAVDLVKHIRSEFGDYFDICVAGYPKGHPEA
TSFEEDVQYLKEKVSAGADFIITQLFFQADTFFNFVKACTAIGITCPILPGIFPIQGYHS
LRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVTMCKELLASGLVPGLHFYTLN
REVATMEVLKRLGMWNEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQAWDEF
PNGRWGNSSSPAFGELKDYYLFCLKSKTPRTELLKMWGEELTSEESVFEVFTYYLSGEPN
QNGYKVTCLPWNDEPLAAETSLMKEELLKVNQRGILTINSQPNINGKPSTDPIVGWGPSG
GYVFQKAYLEFFTSSETVEALLQVLKKYELRVNYHIVNVKGENITNAPELQPNAVTWGIF
PGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYHLVNLVDN
EFPLDNCLWQVLEDTFELLSSPVQ
>A0A845QVG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLTEDSAEEALAMFDEAKVTGVLALRGDRNPDREPAGVFHYANELTAF
IREHRGDMKIYGACYPEKHPQADTLDHDIDNLKRKVDAGATHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDRWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWANVQDLFA
>A0A7U9NXU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli HVH 36|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEIYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1G4K6T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea nothofagi CBS 11611|TrEMBL
MRVSEKLQKNLESSETSKPTFSFEFFVPKTTQGVQNLYDRMDRMYQTRPQFIDITWNAGG
KLSQLSTDLVSTSQSVLGLETCMHLTCTNMPVQLIDDALARAYESGCQNILALRGDPPVT
TGEWKQCEGGFAYAKDLVCYIRQKYGDHFDIGVAGYPEGHPEEEATPQLIQYLKEKVDAG
ANFIITQMFYDADIFIEWCRQVRQAGIDVPIIPGIMPITTYAAFMRRADWCKIKIPDEFM
TKLDAVKDDDQAVREVGTGLIAGMCQKLLKSGYVTHLHMYTMNLEKASMMILDKLGLLTE
EDDIFRDEVVPMPWRKSLHPQRRNESVRPIFWQKRPYSYVARTSQWSADEFPNGRFGDSS
SPAFGDLDLLGSSLIRQSPQRALELWSAPTKLSDITNLVIDYLQGKTKCLPWCDVALNHE
VDSIMPQLLDLNSHEILTLNSQPRVNGLPSGDKVIGWGPNNGYVFQKEYLEFLLPKSKLP
QFMDLIGHDASLTYFSVDASDQLHSNHPDDTAANAVTWGIFPGREVLQPTIVEKVSFLAW
KEEFFHILEEWKLILGEQGHRDSVTLLDTIINDYTLVNVVDNDFVTDGNRIHDHLKCLY
>A0A0Z8F5V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVYQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A259CRW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. 24-46-87|TrEMBL
MELSVEFFPPKTPEGESKLHVVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVREMLK
>A0A4V6Z650|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gordonii|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNEKIIQALREMQDIAPHYISVTASNNKFNIEETTVRLAD
FIYNDLKIPTIAHLPAVYLTKEMVSDTLQALDKVGVHKILALRGDIFPDVAPKDDFKYAT
DLIEYIKEEAPHFDIIGACYPEGHPDSPDRVSDIRNLKKKVDAGCSSLVTQLFFDNDRFY
DFQERCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRS
AGLAYAIDQIVDLVTQDVAGVHLYTMNNAATAHHIYQATHTFFS
>A0A3D8I3M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter marmotae|TrEMBL
MDIESLVGKIQNKSSFLSFEISPNISARLDKELVVALRSLQEVDAFVCTDSPLARFKPSS
ILSSVKLQQALNKPVICTLSMRDRNSIALCGDILAANELGLRTFLTLSGDSIKYGDCKES
KGVFEESSLKLGKIIDSLNAGVALNGKPLKEPVDRIYNFQVINAYANNPQSLIHKIEKKL
GASKVYALFTQPVYSLQAAEFLLTHVEKYNVANHTNCALVLGFYPVMSYKGALFLRDKLP
GVYIPDEWVQKLENAHHKGVDEEKKVGLEISLALLERLKGLHNKFHFMSANKPHLLKSFI
>A0A1M4ZS77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavisolibacter ginsengisoli DSM 18119|TrEMBL
MKVIDHIRESKGTHISFEILPPLKGKGINALWEHLDPLLEFKPSFINVTYHRSESMFKRK
SDGTFDKVEVRKRPGTVGICAAIQNRYKVDAVAHLICGGFSRQETEDALIDLNFLGVDNV
LVLRGDAPRNESFFEPEPGGHRYAIELMNQVMNMNNGIYLEEDLKNAVKTNFCIGVAGYP
EKHFEAPNMQTDLQYLKAKVDAGAEYITTQMFFDNKKYFDFVTACRNAGINVPIIPGLKP
VSTKKQLTVVPRTFHVDIPADLSGEILKCKTDADVEIVGTEWLLQQSKELKAAGVPVLHY
YTLGKPNIISNVVKAIL
>A0A0Z8LVK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELQIPTIAHLPAAYLTKEKVQSILHSLNEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARAIHQAIHSLFKHYS
>A0A248X7H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLTEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAF
IRERRPDMKIYGACYPEKHPQADTLDHDIDNLKRKVDAGVTHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDHWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWTNVQDLFA
>V4LH12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eutrema salsugineum|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALQTIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIGENGLATNAAYQSDLEYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMTGFCKTK
IPSDVMAALEPIKDNEEAVKAYGVHLGTEMCKKILAHGIKSLHLYTLNMEKSALAILMNL
GMIDESRISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLVKINSKGFLTINSQPSVNAERSDSPTVGWGGPAGYVYQKAYLEFFCSKEKLD
AVVEKCKTLPSITYMAVNKGENWVSNTAQSDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFETWSRSWANLYPEADASRNLLEEVKNSYYLVSLVENDYINGNIFAVFADL
>A0A512H7K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararhodospirillum oryzae|TrEMBL
MTAPLPPSAPLIEPFQPAGPLSVSFEFFPPKTEAMQEQLWACIRRLEPLHPSFVSVTYGA
GGSTRERTHETVARIREETTLTPAAHLTCVAATQGEVDAVARAYWDAGVRHIVALRGDPP
EAGTRYQPHPGGYPFALDLVKGLRKVADFEISVAAYPEGHPEATSLDADLDNLKRKIDAG
ATRAITQFFFDVDAYRRFMDRVRAAGITVPVIPGILPVASFSTVTRFAAACGASIPAWMG
PLFEGLDDEPETRKLVAATVAMEQCRALAADGIHNFHFYTLNRPDLVHAICHVLGVRASA
PGTPNAAPADKGERS
>A0A564TPQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gordonii|TrEMBL
MQDLAPHFISVTASNRKFNIEETTVRLADFIYNDLQIPTIAYLLAVYLTKEMVSDTLEAL
DRVGVHKVLALRGDIFPNMEPKKDFTYATDLIEYIKEQAPHFEIIGACYPDSPDRVSDIK
NLKKKVDAGCSSLVTQLFFDNERFYDFQERCTLAGIEVPIHAGIMPILNRNQALRLLKTC
ENIHLPRKFKTILDKYEYDPESLRAAGLAYAIDQIVDLVTQDVAGVHLYTMNNSNTAHQI
YQATHTFFNNKVSS
>J4QAZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp. FOBRC6|TrEMBL
MDIREHIRKEPLVFDGGMGTYYAQKTHTRGKGVELANIETPLVVEEIHTEYLRAGTQAIK
TNTFAANCSVYQGDTALVERILRSGWEIAARAAEPFDAYVFADIGPVTGLPPADILDEYR
FLVDTFLAAGARHFLFETNSSTEGLVETAAHIKQVCPEAFVLTSFSAFPGGYTRDGFFVE
ELIRTVTESGYIDAVGFNCVSGVQSMKELVHLLGTCPLPLSLMPNAGHPIVIDGRTFYES
APDYFGEGLAAIVRDGVSIVGGCCGTTPEHIRALCAALADGGHMSEGASAQAERSTLAPS
CSPFFEALKTGEFPIAVELDPPETGNADKFMVGARELQEAGASAITIADNPIARARMDAA
MLAGRVQRSLGLEPIPHMTCRDRNLNAIKSILLGLSAEGVHNLIAITGDPIPTAERDEVK
SVYQFNSRKLSAFIKSLGERGDVVPFHVFGALNVNSRHFPSQLGLAKKKMEAGMTGFFTQ
PVLSTRAKENLRTARDTLPGALILGGIMPVVSERNARFMESEISGIHVEERIINAYHGLD
RETAEELAVKLSLEIAQDIAPYIDGYYIITPFARTALVARIVKELRRK
>A0A1W5DF10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lasallia pustulata|TrEMBL
MEKITDKIAALPKDGTYFSLEFFPPKTQMGFSNLQARLERMSRALRPLFVTVTWGAGGST
SSKSLELAEICQRQLGLTTCLHLTCTNMRRKLIDEALEEAKALGIRNILALRGDPPRSEE
YRLNDGALEDGGEGEEGDSNEEFTWAIDLVRYIRRVYGDYFCIGVAAYPEGHADESYPEV
QDPLHDLPYLVHKVQAGADFIMTQLFFDVNAYTSFEKLLREHESGAFKDIPIIPGLMPIQ
SYQILKRTTKLSHAKLPPDILDRLEGIKGDDEAVKRVGVDIISEIVEDIKAVKAAGPRGF
HFYTLNLEKALAFILERTKLIQPSTPGSNDDSAIDDSFPFSKGTRAHTNGVNNVDGTGKS
HPRKDFDRRRLSSTTSPHNRIIVDPPPSSHNSTISASEAGHPTSPTLASRATTLAISSGE
GSLGREATWDDFPNGRFGDARSPAYGEIDGYGTSLHVSISYARQLWGAPSTRQEIGKLFV
RHVQGNLESLPWSEGDVNAETAVIRKELVALIDQRGWWTVASQPSVDGVLSSDPVFGWGP
AGGFIFQKSFVELFLPAREWKSRLRPHLESAPVSAEVSWYAGNAAGEFESSEAAEAVNAV
TWGAFPGKEIVTPTIVEESPTRAGLESSRLLVHLSLAYDDLIKHDPGTSNPALMEGSWGS
GIGKNIQSGQEDWRDVEMPEIDSETNEDTNKRAGKKNPRTGEHWSDDEMPEIDYEFDVDG
NNSEKEGPNSRNRHPSQTSFSAPKAPASKDCAAPSSHTRHHCILSGHIFRRERIPLRGDQ
RVGQRTKFDLEERRETCEDCKKDIVEKFSSKLSLSMSNANNNNNNKDTSKTDXPRTYTAA
KRFGGESSSSGKSNPFNSIAPLSAPSITSPTSGASSAFGLGSGAFASFGSSAKTPKTPAA
SLDFGSSLASPSPAAEKREKDFITKDPTENEIKSKPSTSSLESKSSGSTSEHSLKSTWVV
WYRPPTSKYSDYEKSTIPLASFSTVEAFWTVYTHLKRPSTLPTVSDYHIFKKGVRPVWED
EENKRGGKWILRLKKGVCDRYWEDLLLAMVGDQFAEAGEEVCGAVLSIRSGEDVLSVWTR
IDGGRNIKIRETIKRLLAFPSDTNIVWKSHDDSIAQRSAIDQARHEKGNGSGTHHNSAKR
RDTVNEDPTPEKPKASAS
>A0A6P2FED1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. PBL-H6|TrEMBL
MRPPLSFEFFPPKTPEGVVKLRAVRQQLYALRPEFCSVTYGAGGSTHEGTFGTVREILGE
GVDAACHFSCIGATRTTVREQLKELKAMGVKRLVALRGDLPSGYGMGGEFHYASDLVGFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVRAGADAAITQYFFSPEAYFRFVEE
ARRLGLDAPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLVSGGAPALHFYTMNQSVATLALLQRLGWEE
>D8SVM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selaginella moellendorffii|TrEMBL
MKIIDRVKEAWSEDKIVYSFEFMPPRTPKGMKLLLDSLDRIVMFQPSFCDITWRASSSEM
TLEIARKMKTMFGLETMMHLTCVGSTPERIDSALDFVRSHGVENILALRGDPPEGEEALD
VAGSDDLSCALDLVSHIRETYGSSFGIVVAGYPEAHPDVIQADGSATEEDYQKDLAYLKK
KVDAGADLIISQLFYDTDIFLKFVNDCRQIGITCPIVPGILPINDYRKFLRMTTLCRTKV
PADVRDALQSIKDDPVAVRKYGIHLGTEMCKKILAHGIKALHLYTLNSEKTAIEILKNLG
LVDVSKVARPLPPSAQCKQEEG
>A0A6G4B335|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces harenosi|TrEMBL
MALGTASTRTDRARTVRDILAAGKTTYSFEFSAPKTPKGQRNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDKVAAAGCQTPIIPEVMPVTSVKMLERLPKLSNASF
PDELKERILAAQDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQD
>D8QNN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selaginella moellendorffii|TrEMBL
MRIVDKIKDAQRENRTIFSFEYFPPKTDEGVENLFERMDRMVMHQPAFCDITWGAGGSTS
DLTLEIVNKMQNMICVESMMHLTCTNMPVSKLDFALENVKANGVQNILALRGDPPHGQDK
FVQVEDGFSCALDLVKHIRKKYGGYFGITVAGYPEAHPDVISGDAATQEAYEKDLAYLKE
KVDAGGDFVITQLFYDTDLFLRFVNDCREIGITCPIVPGIMPINNYKGFLRMTGFCKTNI
PADITAALEPIKDNDEAVRSFGVHLGTEMCKKILASGINAVHLYTLNMEKSAIAILQNLG
LIDISQVRRSLPWRPPTNVRRTREDVRPIFWANRPKSYISRTTAWDQYPSGRWGDSRSPA
YGALTDYQFLRRRSRNKKIQEEWVVPLSSVEDIAEKFANYCAGKLKSFPWSELEGLQLET
KKINSELVKINKDGFLTINSQPAVNGEKSDSPAVGWGGPGGYVYQKAYVEFFCSPEKLEK
LIRKAEEFPSLTYIAVNSVGETKSNVGPGDVNAVTWGVFPAKEVIQPTVVDPISFMSWKD
EAFQGWEDEWASLYKAQDDPAKKILHEIKESYYLVSLVDNDYIGGDLFAFFSGI
>D8S976|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selaginella moellendorffii|TrEMBL
MKIIDRVKEAWSEDKIVYSFEFMPPRTPKGMKLLLDSLDRIVMFQPSFCDITWRASSSEM
TLEIARKMKTMFGLETMMHLTCVGSTPERIDSALDFVRSHGVENILALRGDPPEGEEALD
VAGSGDLSCALDLVSHIRETYGSSFGIVVAGYPEAHPDVIQADGSATEEDYQKDLAYLKK
KVDAGADLIISQLFYDTDIFLKFVNDCRQIGITCPIVPGILPINDYRKFLRMTTLCKTKV
PADVRDALQSIKDDPVAVRKYGIHLGTEMCKKILAHGIKALHLYTLNSEKTAIEILKNLG
LVDVSKVARPLPPSAQCKQEEG
>A0A2V4FM11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Avibacterium paragallinarum|TrEMBL
MSYAKEIDTLNHYLSGVNGNINVSFEFFPPKNENMEKILWDFIHRLQVLKPKFVSVTYGA
NSGERDRTHSVVKRIKQETGLEAAPHLTGIDATPEELKRIAQDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPAWLAKMYEGL
DDDPTTRNLVAASVAIDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A370K721|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella solisilvae|TrEMBL
MPSISFEFFPPKTEEQRLQLDQAAGLLKSLGPEYVSVTFGAGGSTLSYTGETVARLHSEH
GLDVAPHLSCVGGTRAELAELLDSYRAAGYRRIVALRGDLPSGMATPGDFRYAAELVRFI
REHSGDHFHIEVAAYPEIHPQADDALADLRHFKAKVDAGANGAITQYFFNADAYFRFVED
VRRMGVAVPIVPGIMPISNYFQLKRFSDACGAEIPRWISKRMQAHGDDAASIRELGADVV
AQLCRRLLDGGAPGLHFYTLNRARATRAILDRLHG
>A0A372F094|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium 63075|TrEMBL
MNLSHIGFRATRREIKRENPDMSPQVSFEFFPPKTLEAAFRLHDTVQTLAPYGPRFVSVT
YGAGGTTRALTREAAQTLHKTTGLRVAAHLTCVGASRDETLDVARGYAGTGITDIVALRG
DAEEGAERFTPHASGFANSVELIEALAAEGQFNIKVGAYPERHPDAAHENADIDWLKAKL
DAGASEAITQFFFDPEDFLRFRDKCAAAGIDKPITPGFLPIENWQSTKRFSAKCGASIPA
ALDDAFAKAARDGREELLAIAQATELCDALLCEGVEDLHFYTLNRPELTAKICTALGLEA
RAPLRNVA
>A0A0K2R3G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Hiyo4|TrEMBL
MGVAAYPTRHPESPSEAHDVEVLLAKQCSGADFAITQVFFHTEQYANLISRARRAGSPSP
SSRALCRSPACAGHTARRTDRR
>M6KM61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Pyrogenes str. L0374|TrEMBL
MNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEVEHRP
EEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A5M8PZV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lasallia pustulata|TrEMBL
MHIRDKLAEAERRHRPMFSFEFFPPKTAQGVQNLYDRMDRMHDLGPSFIDVTWGAGGRLS
HLTCEMVNVAQTVYGLETCMHLTCTDMEKEKVDGALKEAYKAGCTNILALRGDPPREKEK
WTAVEGGFRYAKDLIKYIKEKYGDHFDIGVAGYPEGCEDQQDPEILIDHLKEKVDAGGTF
IVTQMFYDVDIFLSWVARCRAKGITVPIVPGIMPIQTHAAFLRRASWSNCHIPQKWSDAL
DPVKNDDAAVRQVGKDLVAGMCQKILDAGIMHLHFYTMNLAQATRMVLEELGLATPDGTP
SKALPWRQSLGLNRREEDVRPIFWKNRNKSYVVRTQDWDEFPNGRWGDSRSPAFGELDAY
GIGLKGTNEQNIKLWGEPRSIRDVADIFIRFLDDEIKSLPWSESPISSEANAIKPELVDL
NRRGFLTINSQPSVNGAKSSDPTYGWGPRGGYVYQKAYLELLISPQLIAELIARMRKDPN
ITYYAVNKAGDLRTNAANDGPNAVTWGVFPGKEILQPTIVETISFLAWKDEAFRLGSDWA
RCHHVSSPSRHLIDNIMENWYLVNIVHNDFHQTHGIFPLFDGLNVKEINQSPESTTNGVH
PHDHNITNGVNGSLTKAIPEHLRN
>A0A2C6E213|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. GCY|TrEMBL
MALTLQEKIIDPNQGVYLIGTTPPKIGTDPEQLKSIAAKLLGRLHEIEYDGVIIYDIQDE
SSRTQVPRPFPFKHTVDPCEYSQLIRELSHLDVITYKSVAQRDSEAFGNWLSSTKQQYGL
NNLVLVGSPSSQGDIKLPLSEAYKVLKHHQDDFFLGGVTIAERHASKRNEHERLIDKTEQ
GCQFFVSQAVYDAQATIDLITSYARTCKQQGQTPKRIILTFTPCGGEKTLQFMEWLGISV
PEATKWRMLDSENTLSESIRICRENLDQILKSCSHLDISLGLNIESLTNRKEEIDASINL
YRLLKATMELCLAEKQIA
>A0A2X4USW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium minutissimum|TrEMBL
MSPRLSASAPLDQISEDTPKRLERTALSFEVIPPRHDADAAKIDRLLATLSAYNPDYIAV
TSSQRSGWLKGTAAFIEKISRDTAMRPLAHLACTAGTEQELIGWIDTLVDAGVRGLLALR
GDLPEEGMPEGHLPHADSLVRLIRRWESARVARLAAGRLAVGVACYPNGHAESATPDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTKVLDRLAAATSSEEEQEIGMQITASLAQSVLNAGADGLHIYTHNNPDITTDLL
NRIGVTP
>A0A413T0L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola coprophilus|TrEMBL
MRVIDLITSSEKTAFSFELLPPLKGTGIERLYGDIDKLKEFDPKYINITTHRSEYVYQEL
GDGLYKRQRLRRRPGTVAVAAAIQQRYGITVVPHMLCSGFTREDTEYVLLDLQFLGITDV
LVLRGDKARHESAFVPEPGGNAHAIELEEQINDFNRGIFVDGSPIRAPHTPFSYGVACYP
EKHEESPNAEQDLLWLKRKVETGADYAVTQLFYDNNRYFSFVKRAREAGITVPIIPGIKP
FSKLSQLTMVPKTFKVDLPDELAREALKCKTDEEARALGTEWCIHQCRELMAGGVPSLHF
YTVGAVDVVRDVAKAIF
>A0A0M4D7Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas soudanensis|TrEMBL
MSLLQQQLSAGRFVVTAEIAPPKGIDTAAALETARALRDVTAVNVTDNQGANMRMAPLAM
AVLLLREGIEPILQLTCRDRNRLALQSDLLGAAALGIENLLLLSGDHPRFGDHPGARPVF
DLDSVQLLQGVEELMAGRDLSGRPLCGLPRFFPGAAATPEAEPFELMFQKYSKKVAAGAR
FFQTQAVFDIPRFEIFMDEARPLKAPVLLGVLLLKSARMARFLNANIPGVRVPEPLIARL
EAASDPLDEGVAIARELVACARLRCQGVHLMTLGCEERIPEILG
>A0A2D6I072|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micrococcales bacterium|TrEMBL
MDGGDLDTVAEAVDRFQPYVDAVNITDNPAAHAHASNVSMAIAVKQLGLEPIMQVVCRDK
NRLAIQADVVGAQMHGVTSFCALTGDDVTAGDEPEARRVFDIDGPQLVSIMRTLSDGTYL
SGRSLKHHRELLIGAVENPFAPPAHVRVRRARMKVDSGARFLQLQIGYEPEKLEAFVQGC
ADNGVCRDAAVLPTVILTKSAGALRFMESSVPGIHVPADVIDRIASASDPLEESYQLARE
QAAHALSLPGIAGIHITDFRHDDSVHRLVRDLRLGPAFSSEGATTHASTTHTQTA
>A0A2H9PCD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desantisbacteria bacterium CG_4_10_14_0_8_um_filter_39_17|TrEMBL
MGALKNALKEGKFVVTGEVGPPKGTDITKLMEEAEIIKNRVVAINVTDIQSAVMRLGSMA
VCHLLKEKGTEPVFQMVCRDRNRLALQSDLLSASVLGIENVLCLTGDYTTLGDHPQTKPV
FDLDSVQLLAAAKGLCEGRDMAGQEIEGSPNFFLGAVVTPGADPIEPQILKMEKKIKAGA
QFFQTQAVYEVDKFAAFMEKVRRLGVPVMAGIVVLKGAKMAEFMNKNVAGVHVPDEIIDE
LKTSTDRVKTTIEISARLIKELKPLCQGVHIMPLGWGHHIPAILDAAGL
>A0A399E2I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meiothermus taiwanensis|TrEMBL
MKVSALLQSGRPIFSFEFFPPKTPQGEAALFRTLHELKPLKPAFVSITYGAGGSERNKTA
EWAARIQKEVGLPAMAHLTCVGSTREELLARLHEYAQAGVENIMALRGDPPKGVQAFQPV
AGGFRYASELVALIRAEFGDRFAVAGGAYPEGHPEAVSLEADLHHLKQKVEAGLDFVVTQ
LFFNNALYFGFVERARRIGIQVPIVPGLMPITDLAQVRRFMDLCGASIPGPLLSRLERAQ
SPEEVLEIGVEHATRQAQELLEAGAPGLHLYTLNKSPATRRVMQNLQMVLR
>A0A1G4Z7T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kosakonia sacchari|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCAATGIDVEIVPGILPVSNFKQAKKFADMTNVRIPAWMSQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A1V3G5E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fictibacillus arsenicus|TrEMBL
MSLVTDLKQNKILIGDGAMGTLLYSYGSDFCYEELNLSQPEQIYNIHRAYLNAGADIIQT
NTYAANYSKLERYGLQDQVKEINKAAVQNARRAAKNQYVLGTIGGIRGIKPNSISLDEIK
RSFREQLYCLLMENVDGIQLETYYDLQELETVLEIARNETSLPIIAQVSLQEIGFLQDRT
PISEALLRLEEIGSDVVGLNCRLGPYHMLKTLEEVPIPKGAFLSAFPNASLPSYSDGKFQ
YESDAEYFKECAHLFRKQGVSVLGGCCGTTPAHIRAFSTELKNLQPVKEKEVKQRKRDIV
IQSASKSNYVPLFEEVKKKQSIIVELDPPRKLDTSRFMEGAKALKKAGIDALTMADNSLA
SPRICNSALSSVVQSELNLRPLVHITCRDRNLIGLQSHLMGLHTHGIREILAVTGDPASV
GDFPGASSVYDVTSFELIKLIKQFNQGLSLSGKELGEKTSFSVGAAFNPNIRLIDKAVER
LEKKIEYGADYFISQPVFSEEKLIETYEATKHIDKPIYIGIMPLTSSQNAEFLHHEVPGI
KLSDDVREQMGKYKENPKQASVVGLNIAKSLLDTAMDLFNGIYLITPFMRYELTVELANY
ARTNHPSLLARRSQNA
>A0A355M8S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaeria bacterium|TrEMBL
MENTFEKRLQESVLIFDGGMGTEIYKKNFFINTCFEELNLSAPKIISEIHKDYAKAGAEV
LTTNTFGANRNKLSKFGFANKVAEINKAGVKLARESAESNIIVAGSAGPIGEIPYNSGVT
STNIIDMLVEQLIALKEGGADFIMFETLPSLRDVQQSIDAIRQVKDIPYVLSMTVNRFGE
TDKGECLSTLLAPLAKMDYKPTAIGINCGLGPEALLSVVEKLSKICSYPIIAQPNAGSPR
SVDNRTIYMTSPEYFTTYVLKYVALGVRGVGGCCGTTPDHIKDLARSVKPTSKNAFAKTI
NLSISEEHLQSPVPTSQKSKLGAKIAAKEWIKTVEIVPPKGYNLKDVINKAKFCKESGVD
AINIPDGPRASSRMSPIITALMIQQQAGIETILHVCCRDRNLIGMQSDLLGCAAAGVNNL
LIITGDPPKLGNYPYASAVFDADSIGMTRIQSNLNRGVDIGGNTIGEKTAALIGVGADPN
AIDMEREFRRTVEKIEAGAEFIITQPVFDVNSLISFYKKIEKFKIPLIAGIWPLASYRNA
EFMKNEVPGVVVPDSIMKRMARYESREDQRAEGISISRESIELIKSFVAGVQVSAPLGNV
ETSLKVLK
>A0A7X8QV06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MKIIEFYKMSQKPVLSLEIFPPRASYPVETIFETIEELRDLKMDFISVTYGAGGSTRDRT
VDIASSIKKDYGIETLAHLTCMAHSRQEVDSILEILWDRGIRNIMALRGDLPLDEEGIDS
IKREYHYAFELIEDARKKADFGIAAAAYPEGHPECEKLKEDLLYLKQKVDAGVDVLVTQF
FFDNRKFYDFIDRGLQIGINCPIVPGIMPVLNAKQIKRMLALSGASIPPALLQLLDKYDT
RPDDMEKAGIEYASRQVEDLIKNKVPGIHLYTMNKSRQIKEIAANAGLK
>A0A2D5N4D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MEKLQAANKRIASDLENAYMEVIPFPDIEKRFEILKPKSHLAVTCSPTKGVDETLQLCEK
LVDRGFQVTPHIAAKCVRDDTHLESIVERIEALNISSIFIPGGDRPEPLGRFSDSYQLLN
SLRKLNHNIKSIGIAAHPEGHPDIDETILMADLIRKKDLATYIVTQMCFDANILGDWLVK
IKDLGVNLPVWAGLPGVIERGRLLKTSLRIGVGDSLRFLRKKSQVASELMRSSTYHPDDL
VANISKYKHINATNLAGYHIFCFNQIETTEKWRAETIALMS
>N1P1U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain CEN.PK113-7D)|TrEMBL
MSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKT
LTLASLAQQTLNIPVCMHLTCTNTEKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVE
AGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
AILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETVANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWET
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKA
WRDEAFSIWSEWAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETDELWEMLLDQA
>X0ZWF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MCFKVNKFKEFVKKARDIGITVPIIPGIKPFTIRKQLASLPINFHISLPQDLVQEILQAS
SKEAARQAGIEYTIYICKELLKFGVPGIHFFSLGQGKDVREVVQAIF
>X0XJ73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
XNMLALTGDHTALGDHQNARPVYDLDSTQLIDLVSKMVDDGTDLEGKEIEGGKIKMNVGC
AANPNSNPREPEILKVGRKVEIGADFIQTQTSFDIDDAKAFLKELERFNVPVLLGLFPIK
NYGIAWYFNEYIPGVSVPKDLLKALKTAKKEYKEDKKKRNDVIDKINIEFFEPFIKEIKK
TTKAAGIHCMAVHYERLFEPLLKNF
>X1FN10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MGDHLEAKPVCDIDSVQLIQLIHNLNSGKDLSGNNLDGGVDFCIGASATSSADPIEPQLI
KFEKKLKAGIDFVQAQAVYNLDELKRFVDYSRNINKNVKILAGIVLLVSAGMAKWMNENI
PGIFVPQNLINELAEVPKGEGLSKGIEIAGNLIKRIKDEKICDGVHIMAIGKEEKVPDIL
KAAGILKD
>X1NCS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
KRVRDRGLHEKVKILAGVAPIKSVGAARYMKTKVPGMDVPDSIIERLRGVPKERVSKEGI
KLCVDIINQVRQIKGVAGIHLMAIEWEETVPEIIEAAGLLPRP
>B1J2V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida (strain W619)|TrEMBL
MSLLKSALREKTFVCVMEFVPKPSAERFAAMEAIMARGHLCGWPMTVAIGDRVGSPLDLS
PLDALPSFSKPVPALPHFSGKDREQHDLLAQLKRMDAAGLDQLLLLTGDRLPGHQPGERP
VRYLESVAALQIARKACPHWLLGAALNPFKYREEEGGAQYFKAEKKLAAGADFLTLQLGF
DASKHQEAMQWMGRQAEPKPLLACLMSLSHGRAAMLEHVAGVTVSPSMRNMLEAEAAVSK
AYAQARGLDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEDWQARVHSQEQWATA
WAGSWQMPGLPAVTFHPPQADWRQGQSRVSATAREKLRYHLLHGFHALLFSHNNWLSKAF
GWAVRRPLWASDSGARWLHSLERSVKRPLLGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVQQTAVLTERLIPCIEIQTRHRSSWPQWFDAQAP
GRLSSQPTLRNPPESSPQAVHRQ
>A0A7S8EJG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. NBSH29|TrEMBL
MIGHQRDENPAGIDLPLEPLPGHSSRGRLERILRRGEFAVTTELNPPDSADPEDVYNRAK
VFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDQGKFLSGRKLTTPPQLFL
GAAINPFAPPYDFRPYRLGKKIAAGAQFVQSQYCFDVPMFREYMQKVRDLGYTEQCFVLC
GVGPLASAKTAKWIRSNVPGIHIPDSIIKRLEGAQDQKKEGKQLAIDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVHESGVLKGRRPWRKEPRADDLLVAERLEHILHDDITETQVEMVD
EARH
>X1B839|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
DAINITDNVRGIPTMSSTACARLVLDVGGEPIMQLTTRDRNRISIESELYGVYALGIRNV
LFITGDRTLMGPHSDAKMVFDIDSIQALHLTSHLMRGTDFAGEELEGTPHFFMGSTFDPY
VDPIEMQVLRAEKKRDAGAQFFQTQAIFDTDRLESFMDLAIDLKLKVLAGIIPLRGPRMA
RFMNKNVPGIKISEEYIKRLESAGKGLKEDAERDAMREEGLLIASEIIKSIRKIKGIDGL
HLMGIGWEESIPELVKRAGLSSRPKVE
>X1JVH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKTKSNLERVLEAGHFAVTGEIGPPPGADPEVIRRKAKILKGNVDAFNVTDGQTAVVRMS
SWAACLIGKEEGLDPIVQMTCRDRNRIALQMDILGAAALGINNILCLTGDHQKFGNHPMA
KGVFDLDSIQFLKVVKDMRDEKKFQCGDEMAVVPNLFIGAAANPFADPFEFRVIRLAKKV
AAGADFIQTQIVYNVDKFAEWMKRVRDRGLHEKVKILAGVAPIKSVGAARYMKTKVPGMD
IPDSIIERLRGVPKEQVSKEGIKLCVDIINQVR
>H6NQX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus mucilaginosus 3016|TrEMBL
MKPGLREALRSQVLVGDGAMGTYLYQMGFPIGISYEELNLLKPDVIMDVHRRYYEAGARL
IETNTFSANREKLSKFGLEGEVEAINRAGVELARRAVGEDAYVVGAVGSIRAGKRKNVRT
NKVREDLREQISILCDTKVDGLLLESFLDLDEMLIALKEVRRISDLPVICQFATEGAGVT
QDGVPLKEAFAKLLEAGADVVGLNCRSGPNGLLRSLEGAAAAEADHPPYSVFPNAGLADY
VDGRYSFPATPQYFGETARRFADLGTRIIGGCCGTTPEHIAAVAGALAGYVPNPEAAKRA
AAAPAAEVAERAAAGAGAEVPTEPSIVDLVRQRHTVIVELDPPKDLDIGKFMEGTEALKK
AGVDALTMADNSLAVTRMSNLALGSIVKERTGIRPLIHIACRDRNLIGTQSHMMGLHALG
IDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKKQANFIIGAA
FNPNVKYLDKAVQRLERKVEAGADYIMTQPVYNAELIEQVYEATKHLSVPIFIGIMPLAS
GNNAEYLHNEVPGIQLSDDVRKRMSGLRGEEGRAMGVQIGRELLDAAMRRFNGIYLMTPF
LAYEMTVQLTEYVWEKAGRRHLSPLPK
>A0A6M8M5T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas graminis|TrEMBL
MSQDRSYSFEFFPTKTDAGHEKLLATARTLASYNPEFFSCTYGAGGSTRDRTINTVLQLE
KEVHVPAAPHLSCVGDSKADLRSLLTQYQQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFH
FVERVRKMGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTASIQAFG
EQVITEMCERLLHGGAPGLHFYTLNQAEPSLAVWNNLNLSAR
>A0A0U3QM26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sulfonivorans|TrEMBL
MSAEAVARIRLEVVPSADLLTQLPAAFDTTGSVSVTCLPHHGPARTVEASVSLARLGYHT
VPHLAARSITGKAELHSLLLQLQQAGVSELFLVAGDRRTPAGPYAWSGELLEAVNAYSPD
FSIGIAGYPEGHPQLSQKQLSSSLGVKAPLASSMVTQMCFSAEAISRYLRTIRKAGIELP
VWVGVPGPVSIRKLVSLGARLGVGRSLKLARGTGMAGALWRRDDFLSYDSGRLIREVHQE
LAGDPLFAGFHVYTFNDLGRLPGLLDDLRALQPTTTLASGNTSIPLFPAKI
>A0A150AJD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flammeovirga sp. SJP92|TrEMBL
MKVIDRLNQAAEDKKTLFSFELLPPVRGKSIQSLFDAIDPLMEFNPAFVDVTYHREEYVY
KELSNGLFEKSIQRHRPGTVAVCAAIMHKYKVDTVPHIICGGFSKEETENILIELNFLGI
ENILALRGDAVKGEASFTPHPEGYAYASELVEHVTKMNEGEFKYADQAGFKGGFSIGVAG
YPEKHMDASNMASDIDFLKKKVELGADYIVTQMFFDNQKYFDFVDRCRAAGITVPILPGI
KPLTTQKQLTLLPSIFKLDFPEELLTEAKKCKNNKEIKELGIEWGIKQSKELIEYGVPGM
HFYSMGRSTSVKDIAEAIF
>A0A0C1DM81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. KMS|TrEMBL
MKVTQHIENANGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKIGGNSFAIDLVKQINELNCGKYLHEVMDVDNKADFCIGVAGY
PEKHLESPSLTSDLKRLKEKVDAGADYVVTQMFFDNSKYFEFVKRAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLINEVDKCKNNVEIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A0B3XZC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas marina|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGA
>A0A3M9MWG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rufibacter immobilis|TrEMBL
MKVTEHLQNADKTLFSFEILPPVKGTSIQSIYEGIDPLMEFKPPFINVTYHREEYVFKER
ENGLLEKITIRKRPGTVGICSAIMNKYHVDAVPHIICGGFSKEETENALMDLNFLGIDNV
LLLRGDAVKTEPGFRPHKDGHAHASDLIQQVVQLNHGHYLDEEMENPVPTDFCIGVAGYP
EKHVEAPNLATDLKYLKHKIDLGAEYIITQMFFDNEKFCDFVKACRAVGIKVPIIPGLKP
LTTKSQLNVLPRYFNIDLPEDLVNAVEAAKTPAEVKQVGIEWTIQQCKELVEFGVPCLHF
YTMSKSEATAAVARAIF
>N9Y6B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium thermobutyricum|TrEMBL
MRIRDLFNEKKLVFSFEVFPPKNTSPIKSIYNALNELSELNPDFISVTYGAGGTSVNNKT
TEISSLIKNVYKIEALAHLTSIGAKKENINFIKERLALEGVENILALRGDKKEECNSGDF
LYASNLMNHLREDFNIIGACYPEGHIENKSIDLEIDNMKRKEENGCSSFISQLFFSNETY
YEFLEKARNSGVKAPIQAGIMPVINKKQIQRIGNLCGAYIPLKFKKIMNRYEHNPEALRE
AGIAYAVEQIIDLSSSSVDGIHLYTMNNPYVARKIKENIKTVLKAVNE
>A0A498RCE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lucifera butyrica|TrEMBL
MQIHSLFGSGKAVVSFEIFPPKPNYSLDTIFATLDGLKELKPDFISVTYGAGGSSTERSI
EIADKVKNEYHIETLAHLTCVGSTRGDIEKVLNRFSNHNIENVLALRGDPPQGQAGFAAS
NPGYKYAGDLVAHIKERTDFCVAAAAYPEGHLECPDLNVHFSHLKAKVDQGVDFLITQLF
FDNNIFFTFLDKARAQGIYCPVVVGIMPVLNAAQIKRMTSLCGASVPDGLQRILEKYANS
AADMEKAGIEYACRQINNLLENHADGIHLYTMNKAEQARIIMHQTGLR
>A0A8J3ZHC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Virgisporangium aurantiacum|TrEMBL
MALGLPSVLPRRHPSIAELVHAAEPTFSFEFFPPKTPAGETLLWQAIRDLEPLRPSFVSI
TYGAGGSTRDTTVALTERVATETTLLPMAHLTAVNHSVAELRHVIGRLAAAGVHDILAVR
GDPPGNPQGDWVRHPEGVLYAADLVRLVKELGDFTVGVAAFPYKHPRSADTEADTAQFVA
KCRAGADFAITQMFFDGDDYLRLRDRVAAAGCDTPIVAGVMPVTTMSTIERSSQLSGAPF
PRHLAEQFERVADDPAAVRALGLEQMCAMCDRLLAEGVPGIHFITLNRSTATREIWQQLS
LSAIG
>A0A241Y1X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDIIDKVLHFSGK
ARDIQDFELFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQ
QILACVMPLTLGRANYMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVKTGKEFIPEITRFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENSLVAKVLIKTEVLSKHSLV
GCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQT
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A2E0L4U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MAKVPFFERLQQADPLLMDGAMATMLHQSGVPINASFDELNLTHPEQVLRIHQAYIEAGA
GLVEANTFGANRFKLTEHGLGDQVARINQAGVELVQQAIAATGRDDIYVAGSVGPLGVRL
KPYGRITHEEARAAFKEQIGAQIAAGIDAVVLETFSDVSEIIEALTAARELDPDLPVICQ
MTFAPDDRTLLGYLPASVARELRDAGARIIGVNCSTGPAQIARVLQAMRQAAPELIFSAM
PNAGYPESVGGRVMYPATEGYFADYALTFKAIGASIIGGCCGTRPEHIAAMHRALADPNH
ALPQVSVREEVREEITDQPEAPTELAYKLHNGNFVVSVEMAPPRSHTPQTLLAAAQLLQD
AGADVINVADSPTARMRMSPWAICHLLQSRLGIETVLHFPTRGRNLLRVQGDLLASHTLG
LRNLFVVMGDPTHIGDYPNANDTYDVAPSDLIGLIKHGLNQGVDQAGNSIGQPTSFNVAC
ALNMCASDIDREIRVLRKKLAGGADFALSQGVFEPERIEQFHKRYEELEGKPFDLPVLLG
VMPLYSVKHARFLHNEVPGIHIPDSIFKRLEDAGDHAAQEGVAIAGELLASMSGLVQGAY
IIPAYGRYDLAAEVIDGIRSKARA
>A0A7C2ZWG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MEISLTMQRKKLSKKLPDKSSFTIVTELTGGPGFNFAPIEKFLETYKAAGSSVIPAEFDF
AGITIPQNPGGAANIEPADVLSQAMLKNLLGELDFVPHISCKDANADALTSSLVGFRKAG
VESLLVLTGDKPTKAKGVFELDSIGLLQLIRNMNNNAYIKARPDTLDKVHQFFPGAAVSP
FKYTQSSQMQQYYKMKKKAASGAKFFITQVGWDWKKSLELFRYADENNLDVPIIGNVYLL
STISPAPRLMHDIKLPGCFVSDELLAKLSSETLDEHIERAAQQVAMYKAIGAAGVDIGGV
RNFEMFTKILNRAAEIGTDWERFKDNLCWPKKNGFYLYDRAGKKAPSSQYRKTPGQRFFN
LFHRVVLNQDYRGFHIFKKIMAALGTEKGKGCAYKLFNASEKFFKYLIFDCEECGDCFLP
ENFSWCTIGRCEKRMNNAPCGDSTVDGYCGNNLERLCVGELVYQAAAAEKGGLKRLRATI
NKPRNTALEHTSSILNYLFGKDHTMKNPLISIGESVHASIPKTGKIMKQLAELGDDAYSK
PSPPLDYIKALIESQAADGADYIAVNLDAFGENDPQTTVDMMTEYVRMVRKWAGGVPICI
DSSNNDVLIAGLKEWYNTSESVKRPLINSVKVYTMDKLLGLKKDYDYALVGLLVSEEAST
GPGGSHSVDELYALAKRIFDAAVGQYGFKPNEIFFDSTVFPLAIDMPMEPNVPGYTYRAF
ETIKKIKTDAKMKGVHCSLGVSNCVSDLPGRKIGVCRAYVAKAMEYGLDAAIVNVAHHYG
LVEPAADLLELVDAYAKMDGSAERMNKAMALMGEFCQKNRKPPKK
>A0A7I7U6W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium parafortuitum|TrEMBL
MPRLWQYHDRSVRNTAAGNSRTAEDYFAVWAGIPARDMTGDDAVVQDCPKRMTFGPCGGV
HPDGRCEMRPGPCAFPEVVLWPSGSTPLVPAPQSPAAPLILTDFSCAPYDPVDVAATATA
LSASCDAVLVGEHQNRPDFPPTLMGRLLLDAGVTPWITLSCRDRNRVVLEQELRGLSLLG
VRTVLCVTGDGRGYDVHPDITQTFDLDGPRLVELATSLGMTAAVPETPTAPPVAGRPLRL
VQKQRAGARVAVLNHVCTPELIARFMSDARAAGLTIPVLAAVAVFTDEVSAAVLQGLPGL
ALDPDVVERVLAAPDPVEAGIEAAVAEARALLAIDGVDGVNVSGLASAAGTRAGAQIKAE
VGARIRAEGWGR
>A0A800JAX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lambdaproteobacteria bacterium|TrEMBL
GAGGTSRENTHELAAHIHHDLDVPAMAHLTCVAHTVEEIDVVLSNLKNSEITNVMALRGD
PTAGTKHFVQPKGGYHYASELITAIREHSDFGIGAAGYPEGHVENPDKDDDRKHLHEKIA
AGAEFVITQFFLENTHFLRWRDQLRREGVNVPLVAGILPPSNWKATKHMSEMCGVSIPED
LAQALIKNETDPEASREIGFDHVENQFEELLQEGVEGVHLYALNRLSTVERLGPILKDAS
GTISTPHL
>A0A8D9XB17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella pinnipedialis M163/99/10|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A850FCT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia solanacearum|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRDILDTYRANGIRRLVALRGDLPSGMGEIGEFRFANELVEF
IRKEMNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAGATRAIWQRLGL
>A0A8I2BJF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus str. XMU1401|TrEMBL
MKSKLQQTLEKRSKVITAELMPPRGGSPIRSLKIAQLLKDKVHAVNITDGSRAVMRMCSL
AMSKLLLENGVEPVMQISCRDRNKIALQSDILGANALGIKNILCITGDSVKAGDQQDAKA
VHEFESVRLLKQIQAFNKGIDPTLGELSDKKTFIFAGAAADPNCRNKRSLENRMKKKKEA
GAGFIQTQMVMEKENLIEFCEKISKPLEIPVIAGVFLLKSYKNALFINKYVPGADIPVNI
LNRLKDAKEPLQEGIKIAAEQAHDFMNIANGVHLMAVKAEHLIPEIIEKANLSLEY
>A0A6G3Q076|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID12488|TrEMBL
MRGLRGLRELLERVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLVGRLAA
HGYRVVPHVPARLLRDDTHLKDVVDRLRETGVRDVFVPAGDANPPAGAYEGALPVLRRLG
ELGSPFTHVGVTGYPESHPLIHDDVTIQAMWDKREHATYIVSNLCFDSRVLGEWVGRIRG
REVSLPVYVGVAGPVQRAKLLSMATKIGVGESTRFLTKHASWFLRFAAPGGYSPERLLSR
MRGALTAPGAGVAGLHLFTFNQVAETERWRRAVLERLGG
>A0A351X368|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MLAKAGSNSYWAEVEMETRTKFLEKIQADRPLISDGAMGTLLHQRGVSFDQSFDELNLTS
PALVADIHREYIDAGSNIIQTNTFGANRYKLAQHGLEKRVSEINTNAVELARRVVLASYK
DVLIAGDVGPLGVRLAPFGRVQPEEARIVFREQIDALISANVDLLIIETMTDLYELREAI
LAARDINSDIPVVASMTFTRDDRTLLGDDPAKVARKLREAGADVIGVNCSGGPNQILRIL
KQMVQAVPQGKFSVMPNAGWPEQVAGRIMYPASPEYFADYALAFWHAGACLIGGCCGTTP
KHIAVMHQAIENAPSGSAPNGFTLTAVEREEAAPEGMQPTQLAEKLANGQFVFAVEVDPP
RGLTAQKLMAGSSLLKEAGADVINVADSPMARMRMSPWAVCRLIQEKVGMETVLHFPTRG
RNLLRVQGDLLAAHALGVRNVFVVMGDPTAIGDYPDAMDNYDLVPSGLIKLIKQGFNTGV
DHAGADIGQPTSFFAGCALNLTAADPDNEIKNLRRKLRAGADFILTQPIYDPPAAKAFIE
RAAEELGGLKVPVLIGLLPLVSARHAAFLQHEVPGIEIPDDVQSRMTLSGEREARTGIEI
AIELIHQIKQFAQGIYLMPAFNRFDYAAEIIETIREGN
>A0A7J8KCZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rousettus aegyptiacus|TrEMBL
MVNEPRGHGSLNPRLEGSSSESSKDSSRCSTPGLDPERHERLKEKMRRRMESGDKWFSLE
FFPPRTAQGAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLE
TILHMTCCRQSREEITGHLHKAKRLGLKNIMALRGDPIGDQWEDVEGGFCHAVDLVKHIR
SEFGDYFDICVAGYPTGHPDTGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKAC
SEIGITCPILPGIFPIQGYHSLRQLVKLSRLEVPQQMKDVIEPIKDNDAAIRNYGIEQAV
SLCQKLLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRLLPWTVSAHPKRREEDVR
PIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREQLLKMWGE
ELASEESILTINSQPNVNGLPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKK
YEQRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALW
IEQWGKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWHVVEDTFELLSRPGSE
>A0A1B8DQY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. 23342-1-I1|TrEMBL
MHIKDMLNQGEQAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHA
QLTCEMVSVAQSVYGLETCMHLTCTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEK
WVATDEGFQYARDLVRYIRKTYGNHFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATF
IVTQMFYDVPNFLDWVKKVRAKGINIPIIPGIMPISTYASFLRRCNHMNAKIPPGWIEAM
EPVKNDDAAVREIGRGLVTGMCRAILESGINHLHFYTMNLAQATRGVLEQLEMLPSEERP
LKQALPWRQSLGLGRRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSVKDIANVFLRYLNADVESLPWSEAPISNEADVIKNQLVG
LNERGLLTINSQPAVDGVKSSHPVYGWGPLNGYVYQKAYLELLVAPELIDELLDRIAKDP
EVTYYAVTKTGTLRTNAPSDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHEASSPSRNVIQRVMETYYLVNIVHNDFHHRDGLFSLFEGLSVPNIDQPAEGDVAPA
AVPTPAAAAAATNGTKVEDVSPAIVSNVLPVA
>A0A1B8EC23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. 23342-1-I1|TrEMBL
MADSPTTDKLTDKIAALPHDASYFSLEFFPPKTAMGTTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSKALVDDALSAAKEAGIQNILALRGD
EPRGEYKDALEEGKEGEDEFVWAIDLVRYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
EHDLPYLVDKVQAGADFIMTQLFYDVDAYDNFEKVLRDHSSGAFKSIPIIPGLMPIQSYQ
ILRRTTKLSNAKLPQSIVDRLDAVRSDDEMVKKVGVDILAEIVESVKATKSRTKGPKGFH
FYTLNLEKAVAFILERANLIPSFTPVLTSDASAVEDITDTIPLPQLLINGERKNRRQSSV
GSGPHNFVIIDREEASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRPDITSIFVQYLNGTLSALPWSDE
PITAETNLIKDELIKLNQKGWWTIASQPAVNGARSQDEVVGWGPKGGWVFQKAFVELFVP
TSDWARLKPLLEGNAEVSFLAQSASGEFLKSKLDLGPGEEGTETNAVTWGVFPGKEIVSP
TIVEEVSFRAWSEEAWQMWEEWAAVFGKSGEESRRFLDGVAKDGWLVNVIWHDFVGMCKA
KEGRSEEEGYKGLWDVLIEA
>A0A1Q5DLY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB01249|TrEMBL
MALGTPSTRTDHARTVREMLATGATSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVKATQDIAAESTLTPVAHLTAVDHSIAELRNMVGQFADAGIRNILALR
GDPPGDPMGPWVEHPQGVKYAADLVRLIKEAGDFCVGVAAFPERHPRSDDWDTDIRHFVD
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCETPIIPEVMPVTSVRQLERFPQLSNATL
PDELKDAILAAKDDPAAVRSIGIDFATRFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A6FI54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moritella sp. PE36|TrEMBL
MSFHNAQNIEVLNQSVSELGRDINVSFEFFPPNSPAMTSTLWESINRLKALNPKFVSVTY
GANSGTRDRTHDIIKQIKHETGLIAAPHLTCIDANRQELKQIATDYWDNGIRNIVALRGD
LPPGLNQPDMYAADLVALLKEVNDFDISVAAYPEVHPEAKNAQADLLALKDKIDAGADRA
ISQFFFDTESFLRFRDRCAAVGIDKEIVPGILPVSNYKTLCKFSKLTNVKVPNWMHSQFE
GLDNDQATRNLVGASIAIDQVKVLSREGVKDFHFYTLNRADLTYAICHTLGVRPR
>A0A4D6Y4N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MYTVSQYHQDMIYQRRDNIRHCIKCSFELFPPKNSIAEEHFWHVVEKLSKLKPTFFSVTH
GANNGERQKTYDFVKKIYKKTGINTAAHLTCVNTSTKELKKTAEEYWNNGIKSIIALRGD
TSEKNYKHHMYAVDLVNLLKKIENFDIAVAAYPELHPESKNVQCDIMNLKKKIDAGANRA
ITQFFFNVEHYLYFRDNCVKNKIHVEIIPGILPVYSFNQLQRFSKMTNVTIPNWMFEIFY
GLNSDLVTQQFIGCSIVLDMVKVLSREGVKNFHFYTLNKSEIVYVVCHMLGL
>N9M305|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 713|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAADLVR
FIREYSGDHFKIEVAAYPEMHPQAESFDQDIQHFVEKVQAGANAALTQFFFNPDAYFYFV
ERIQKAGIDIPVAPGIMPISNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A0X3ALG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apibacter mensalis|TrEMBL
MKVTEHISNANGKTLFSFEILPPKKGEDLQNIFSNIDPLMEFNPPFIDVTYHREEYEYRE
LPNGLIQKIVTRKRPGTVGICAAIQQKYKVDAVPHLICGGFNKEETENILIDFNFLGIDN
ILVLRGDPIKSEGIFKPHSQGHSYANELVSQVENMNSGKYLHEEYANGATDFCIGIAGYP
EKHFESPNLDTDLNYLKQKINAGADYIVTQLFFDNNKYFDFVSKCRSIGINVPIIPGIKP
VSIKKHLTALPNIFHIDMPQELVMAVEKCKDNKSVYEVGIEWTVNQCKELMKHGVPVLHF
YSMGRSENITKIAKKLF
>A0A375YMV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium parafortuitum|TrEMBL
MWTGIPARNMTGDDAVVQDCPKRMTFGPCGGVHPDGRCEMRPGPCAFPEVVLWPSDPAPH
VPAPQAPLVLTDFSCAPYDPADVAATATALSSSCDAVLVGEHQNRPDFPPTLMGRLLLDA
GVTPWITLSCRDRNRVVLEQELRGLSLLGVRTVLCVTGDGRGYDVRPDVTQTFDLDGPRL
VELATSLGMTAAVPETPTAPPVAGRPLRLVQKQRAGARVAVLNHVSTPELIADFMSGARA
AGLTIPVLAAVAVFTDEVSAAVLQGLPGLALDPDVVERVLAAADPVEAGIEAAVAEARAL
LAIDGVDGVNVSGLASAAGTRAGAQIKAEVGARIRAEGWGR
>A0A0C5RZM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida S13.1.2|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRTLLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFETDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A4S5JIR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp. SB9B|TrEMBL
MSKQPVISCEFFPPKTEKGAQNLLLVQEQLSVLKPEFYSVTFGAGGSTQDNTLEAVVAIQ
QRAAETGIGAAPHLSCVGSSKERIRTILQTYIDNDISRLVALRGDLPSGMRDPGDFRYAN
ELVDFIRKETGDHFTIEVAAYPEVHPQAQDANSDFENFKRKVDAGADSAITQYFYNIDAY
LYFADRCMQAGIEIPIIPGIMPINNYSQLARFSSGCGAEIPRWLRKKLEAYYDDIPSMQA
FTTDFLTDFTEQLMEIEVPGLHFYSMNKSEPVLTVCERLGLVL
>A0A6M0T294|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSITTIYETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTKEDIDLIIKELKENNIENVLALRGDIPKDKDIIGE
YNYAFKLIEKIKENNNFGISGACYPEGHIECKSLDQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQQKSINVPIQAGIMPVVNKKQIERIVKISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A3R6X662|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. AF12-17LB|TrEMBL
MNIKEYIKEQRLITDGAMGTYYEEKYSEDTVIAEKENLKNPEQIKEIHLEYLRAGARLIR
TNTFAANTMFLADMQEVKETVRAGYEIAKEAVTAFQAENGKEIPVFIGADLGPIYDLDHQ
DYDNVLQEYKEICDTFLSCGADCFVFETQSDFTYIEPVTAYIKEKSDAFILVQFAFDKSG
YTRSGLSMQRVAVEASEMENVDAYGFNCELDSTHMYQFMKNLKFSSDKFVSALPNAGYPY
TLRGKTIYSNNASYYAEKMKDIAALGTDILGGCCGTTPEYIALLSGELQDVPKAVKKIEN
VVTQEVTRTPSIFEEKLSRGEKAYIVELDPPFSEDASKVMKGAEDLRKCNVDLITLSDSP
MARARMDAGQLAVKIQQKTGVAVMPHISCRDRNVIALRAGLLGMHMNDVRHFLIVTGDPV
SRADRERVTSVFDFNSIKLMQYVKEMNLEVFAQEPVYYGGALNYHGANPDAIIERMKRKA
EAGCGYFLTQPVYTEEDVERLTYIKEHIDTKIMCGIMPLVSYKNAMFVKNEMPGIHVSDE
IVNRYREDMTREEAEEVAIELSVEIAAKLYDIADGFYFMTPFNRTGLIARIIEAIRQEEE
RR
>A0A1V5X885|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium ADurb.Bin207|TrEMBL
MRKPFRERLEEGTVLFDGGMGTMLYTKGIYINTCFDELNITAPHLVRQVHDEYLRAGADA
IETNTFGASSYKLEPFGLAQKLHEINLRGAQIAREAAGDDVYVAGAIGPLGVPIEPIGRV
GFDEARADFAKRVRALREGGVDLIILETFLYLSELEQAILAVRDECDLPVIAQVVIRNGE
TLAVGTPISDAVARINGFYPDMVGFNCAVGPKEMLDALETAVALTSRPISLMPNAGEPRR
VEGRTIYLGSPEYFAEFSKRFVQTGARIIGGCCGTTPEHIKAMRRAIAALEPAPRHQIQV
RELQAQAPPEITPYSPQDKSRLSCRLADHKYVTLCELVSPKGVDAERVLKQARQLAHHGV
DAINIPDGPRASSRMSALALAILIQRNVNIEVLLHYTCRDRNVIGMQSDLLGAWALGIRN
ILAVTGDPPKLGNYPDATAVYDVDAIGLTNLLWRLNHGLDIARNPIGEPTGFLVGVGANP
GAINLEEELRRLEYKIEAGAEFIITQPVFDLRIFETFLRRIEPIRVPVLSGIWPLVSLRN
AEFLNHEVPGASVPDDVMEKMRAAKSKEEALAVGTAVAQQMVRHVRPHTQGIQIAVPFGR
VDMVLEVLDGVL
>A0A355W4E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MGNTKHTKEQIRERIQQKKILFDGAFGTYYGGKYDTKQLPELANLEAPERVREIHTEYLE
AGAQILRTNTFAANSFCMDRSKEQIEETLRSGVRLAREAVAAWRERTGETKEVYIAGDIG
QIPGDALAQKDTLCREYKEICRIFLEEGADFFVFETFSEMEELLPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGEAKEIDAVGFNCGVGPSHMHRILQILEKPEGKLLTALP
NAGYPQMVTGRMLFTGDNKDYFVDRMQQMTALGVDMAGGCCGTTPEYIAELAGKLDLTQY
PQAKKDTEPEKKQAPKEDRSFYHTKEAEGRNRKLIAVELAPPMGIDDEKLMDAAHLLQKS
GVDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGI
QNFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFTQAPANYGGAINQSRRNL
EVEIGRVKKKMAAGATFFLTQPISTQESADRVRRIKEETGARILCGIMPFVSLKNATFMK
NEMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVIVMTEDFADGYYFSFPFNRVTMLE
KILN
>A0A3D0HM26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MVFLDIFQGKIYNEKSDKRQLEWRIQVIDSLVEKLKKKVVLADGAMGTYFSQKYMTEMEA
EEANIATPERIIAIHKEYIEAGAELIRTNTFAVNHGLFETAEKRKEVIEAAVANAREAVR
QSRKEVVVAASVGPIRQSAEEEDGEIWKEYTQMLDVFYDLGIRAFLFETFSELRWLPKLA
EYCKNLEEQTIVIAELALNPMGYTQHGFGMAEILQELTADDNFDIVGFNCGVGALHMKKL
LERQYFPKECLLSVFPNAGYQQEMQGRTQVFHDTAYYAGQMKAILALGANLVGGCCGTTP
GHIRALKKVVQQQEQVQPKKVAEKDENVDEIKDNPTPFVRKLREGKKVFVVELDAPFDAS
SDKFRKGVCALQENGVDIITVSDSPMARSRADASLLAVYAKKCADVEIMPHVAMRDRNLI
GLRSEILGAHVNGIRDFLVITGDPVGSNDRGKITGVFDVNSIRFMEYLKHMNEEVLQEEP
VYYGGALNYAGVNPAAIAGRMKKKMEAGCQYFLTQPVFTAEDIDRIRELKELTGARILCG
IMPLVSYRNAMFMKNEMPGIHVSDEIVSQYQPDMTKEDAEETAVKISLEVAEKLLEVADG
FYLMTPFHRVALVNRIIDGIRKLLG
>A0A7U9RQA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MRLDTILLKNDVTLSFEVFPPKVTANYESVKEAAYGVAKLNPSYMSVTYGAGGSTGGNTL
KLAKGIQREYGVTTIAHLTCVGATKEGIRQALSDMKEAGIENVLALRGDRPKDFVGEPFI
DYHYASELVEDIQEFGGMCIGGACYPEGHVESENTQEDILNLKKKVDAGCAYLTTQMFFD
NNIFYNFLSRVREAGIGVPIIPGIMPITRPTQLHSAVRLSGCNVPMRFRSIVDCFGKNPE
AMQQAGIIYATDQIIDLIANGIKHIHVYSMNKPEVVKGIQESLCKII
>A0A7U9SVY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MSLRPDERTLHRCKISNTQDKKEDSMKIRDILRDERPHISFEVFPPKKDSGYDSVLSATE
KIAALKPSFISVTYGAGGGTSKNTVSIASHIKNDFNVTSLAHLTCVSSTKETVHQVIGQL
KENGIENILALRGDIPQEVDFPLPHHYRYASELIEDIRKEGDFCIGAACYPEGHVEAEHK
MDDILNLRHKVDCGVDFLTTQMFFDNNILYNFLYRIREKGITVPVLPGIMPVTNKKQIAR
IGGMSGTALPERFRAIVDCFGDNPAAMQQAGIAYATDQIIDLIANGIRHIHVYSMNKPEV
AEAIMRNLSEIVTV
>A0A2N1U3K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Riflebacteria bacterium HGW-Riflebacteria-2|TrEMBL
MCPNLTTGEKQLQDFREFAEKNLVIFDGAMGTRLYEKGVYINRVYDELNLSQPALVQEVH
REYLAAGAMVLETNTFGANRFKLEPHGLADKLEVINFQAAKLAREVAGNSAWVAGSIGPL
GIRIEPWGKTSVEEAEEAFAEQASGLLAGGVDMFILETFFDINEIHQAINAVRKLSDKPI
IASMTINEDGNALYGTTVDVFTPKLESWGADFIGLNCSVGPKTMYDAIEKMHSLTRLGLI
AQPNAGLPRVVDGRMIYLCNPEYFGEYARRFFQLGVRMVGGCCGTTPEHIKWVANSAKAL
SPGGKSNMLQKFRQVEDVEAQVEVVALSQKSALGKKLADKKFVVTAELTPPKGCDPEQVI
RRAQQLKEAGIDAINIPDGPRASARLSPLAMSLLIEQKVGIETILHYCCRDRNILGIQSD
LLGAYAIGLRNILAITGDPPKVGNYPQATAVFDIDSIGLVNVIHRLNHGRDLGNNAIGKP
TGFVCGVGANPGAIDIDLEVSRFEWKVDAGAEYVITQPVFDIELLERFLDRISHVRIPVF
AGIWPLASLKNAEFMNNEVPGASVPEPLLKRMRKADTIEAQREEGVAIAREALERVRGIV
DGVQISVPFGRVENVLKVIEVLG
>A0A8J2VKL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pullulanibacillus camelliae|TrEMBL
MGLLEELNRRVLVADGAMGTLLYHIGIDRCFEELNRSQPEQVLGVHQAYIEAGAEVIQTN
TYAANVHKLARYNLQDELVSINRAGVELARQAAKDQAYVLGTIGGVYGVNKDVVTLEEIT
LGVEKQLGALLESGIDGVLLETYYNLEELKETLALVRRTTALPIIAQVSLHDIGFLQDGT
PLVEAFSQLQELGADVVGLNCHFGPFHMIQSLKNVPLPERAFLSAYPNAGLPEYNDGRFI
YQSEPSYFEKSAHELRSEGVRLIGGCCGTTPAHIQAMVQGLKGEVPVTDKRVTRSAHVEA
LHIVERSDFHEQPFHQLAKEKPSIIVELDPPRHLDTGRFFEGVQALEAAGIDALTMADNS
LASPRIANMSLASIIKDRYNVRPLVHVACRDRNLIGLQSHLLGLSALGIHQLLAITGDPT
KIGDFPGATSVYDYSSFDLISLCKQFNQGRSATGASLGMRTNFSVGAAFNPNVHHLEKAV
RRMEKKIAAGADYFMTQPVFDQSQIERIYKATKHLKTPIYIGIMPLVSAQNAEFLHHEVP
GIRLTEPILDRMGQYAKDKKAACKEGLAIAKSLLDTALNYFSGVYIMTPFMRYDLSVELV
DYVHQVMGADLRSRS
>A0A873ZFD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus rhamnosus|TrEMBL
MKISQCFKDHQVISFEVFPPRKNATNIAMRPILNTLDAVKAADPDFVSVTFGASGNKPHM
GTLEVAKLIKNEFNLEPVAHLPAAQLTRAQVDAELRGFQEAGIDNILALRGDIPKSGRVS
EDFPYACNLIEHIHQVGDFDVVGACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYQFRERAALAGINVPIEAGIMPVINEHQIERMATMAGVHLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPVVKRIAAATQTIRNA
>A0A101L5A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. EPSL27|TrEMBL
MSPPSLIDTHPNLAGTAPVALSYELFPPRSPAAAESLWTTIGELESTDPDYVSVTYGASG
SNRDTAVELINRLVQETTLRPLAHLTCVGNSPQELADIIGELLDVGVRGILALRGDQPKD
GGAPPEGSLKYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLLSRARRAGVTIPIIPGVMPLTSIRRLTRLRELTGVE
PAPELIERLAAADTDAERTRIGVRATVDLANAALAAGAPGLHLYTFNEHTAALDVLDKLA
LARPRRGNKHRGNKHSGNKHRQLAS
>A0A3D4XC33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKITEAFERGEFVVTAEVGPPKGFHIEKMLEEAKEYLSGITAVNVTDNQSSVMRLGSLAT
CKALKDQGLTPIFQMTCRDRNRIALESDLLSAALFGIENLLLLTGDHTKLGDHPQAKPVF
DLDSVSLIHAVKQLESGVDLGGNELVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVYEPEKFIQFMEKAKQFGKPVQLGIVIPKSVGMCRYMNANVAGIHIPEDMIAE
LKADKEKTKAGITGVEIAARVIRECRPYCQGVHIMAMGWESKVPGLLKQAGL
>A0A3B8S7L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIKDILNKKQPTLSFEVFPPKKDSDYMKVEEATIKIAKLKPAFMSVTYGAGGGTSKHTV
DIAAKLYNGCGVTPLAHLTCASSTKEEVGSQLGRLKEQGIENILALRGDRVAGRESAGEE
EYQYASELVRAIKNYGDFCIGAACYPEGHVETANRKEDIVHLKEKVDAGCDFLTTQMFFD
NNILYNYLYQLREAGIHVPVIAGIMPVTNPGQIKRICELSGTVLPQRFKAIVEKFGDNKE
AMEQAGIAYATDQIIDLYANGVNAVHVYSMNKPEVASSIYHNISKIIG
>A0A2M9GEN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. S10E 269|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISTMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A372I9Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium W635|TrEMBL
MDEPFHAGQPRDALLRRLYEARGSLPLSFEVFPPKEEAGHTALQETIDRLAPTAGHGFSV
TMGRGGATRDLTIETATGIAARTGRPVMAHLVSLGMTRDTVLETADKLWLAGIRHILALR
GDRPDWPAPMPPGFAHASELVAALRAQHDFEIAVAAHPETHPEAESADADIDHLKRKLDT
GAGAAYCQFVLDPAAYGRFIEGCARRGIDAPIIPGLMPMARWPRVRRFARMNGTAVPDWL
DRLFAEAEATPELEPYLAAAMTVEHARRLVAYGAPSLHVYTMNRWPLPMTLAAFIGET
>A0A3D2KG32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MMIKDIYQKGKTVFSFEVFPPKRNDDIYDIYRTLDQLKTLNPDFISVTYGAGGSNSKKTA
TIASYIQNICEIEAIAHMTAVSMNQDTLLHFLDGLRQKGVCNVLALRGDRPRDMSDEDYN
NRTFLHASDIIKVIHSHSDLCVAAACYPEIHPESANRADDLHYLKEKVDAGVNFLLTQMF
FNNEKFYEFRALADKEGIHIPISAGIMPITSAKQLGTSVSLSGTSVPPALSSMVAKYAES
PEDLRKAGLDYAINQINDLIANDVDGIHIYTMNNASTASYIMKHIIKKS
>A0A146H906|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycena chlorophos|TrEMBL
MKVTQKINQADKENKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPASKVDVALREAKLSGCRNVLALRGDPPAGKDE
WEAVEGGYVHGIDLVKHIRREYGDYFDIAVAGFPQHQLLSPEERDQEMKWLKEKVDAGVD
FIFTQMFYDVQIFIDWVHSVRAAGITIPIVPGIAPIQTWNGFMRATSLAKTIIPQPFLDA
LEPHQNDDEKVRAIGTKLVAEMCRKILDENLGIRGLHFYTMNLEKGTKMLLEELNLVPRV
ETVKPLPWRQSLTPTRRTETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGEPKSFTDVADLFARFCGRSLKALPWSDQAPAGETSIIASQLA
RMNRYGFLTINSQPAVNGAKSEDPVVGWGPRNGYVYQKAYLEFFVQPELLSLLLTHIERD
SNITYYVINARGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGQQ
WAKIYDAGSQSRKLISELMDTCFLVNVVHNDFHDTEAIFQPFFKAGEEYLADTSFASLDC
AHYVPDDSLLAESLTLSSMSSSTSSTPPLPAGCMVPLSVIIGHFDGPIMLQPSIVSKATP
TAPTPPRLRTMIKEKLLIETWLNGVDPDAVEHTPWGDITLDNPVPWKSEGSLYTPQAFKS
KFTSARRSQSPEEQQQPDTETETPVFQSRRVKNRNALVFEREIILHADGKSNRVSLQADA
DAMEPEVAAMLSELQDLNSFFKKQDALPPPPSLIVSNSHFSLPVSFESPSKQIPKAVLPL
AARRGKVLPPVAIKHLSDGNDYPGMPTAFLGSPSAYSPQFELSPQQERSSMDLQEMVTSL
RSQCASIEPASPVDERTIEVTPPTPEEDEWAFADGILDFYSPSPFESQFVKKPLRPDLVD
YAAESFSTRSPSRAESLNRQPSAPPSTPLPPCPSPVQRVSVRSILKSSKSVRFAEELEVD
IAESPVPPPRSYRHHSTPPKPRDSMMPALPRSTIHDPLRSPPPRSVSKLQSRPTTRQRRA
TTPASFGSTSPASSPSRTRGLSVTTETNTNTNANAGSGVGVSPVKDAIPASGRHSLGRVF
AKEKENKVPGGREMRRASMHVPVIGSAVATTTKSRMPVPLRNILTRFK
>A0A6N9SNY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrovum sp|TrEMBL
FQEKVEAGADSAITQYFYNPDAYFSFVEDCGAAGITVPIVPGIMPIANFSQLSRFSDACG
AEIPRWIRQKMQGYGDDSASIKAFGLEVVTHLCDRLLEGGAPGLHFYTMNSAGLTSVIWE
RLHLT
>A0A7Y5AEK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CM27|TrEMBL
LARFSDACGAEIPRWIRKQLEAYADDTASIQAFGEEVITRMCEQLLQGGAPGLHFYTLNQ
AEPSLAIWNNLKLPR
>A0A6I6GYL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas alkylphenolica|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKEDLRSLLSQYKAAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHIEIAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVNSIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A7W8STX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. WSM4180|TrEMBL
MTFLTMNPIELSFEFFPPKTQEGIDKLRATRAELVSLKPKFVSVTFGAGGSTQQGTLDTV
VDMAKEGLEAAPHLSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGAVGELRYAS
ELVSFIRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAY
FRFVDDARQLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRA
FGLDVVTDLCQRLVDAKVPGLHFYTLNAATSTKAICERLAV
>A0A2E1W5N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MLKDKILNKEPGIVLYGMTPPKETTDVANIKNIASKHLNRIKSLDIDGVVLYDIQDESVR
NNEERPFPFLPTFEPQKYSGDFLADLELPKVLFQVVGKHSEDTLKNWMQNNLSKGDLGVF
IGNSSSSQASKVSLNXAYNLRREFAXDMLVGGVAIPERHFAKKDEHLRMASKIELGASYF
TTQAVYNVEASKNMLSDYYYYSKSKNLPLVPIMMTFSPCGSKKTMEFMKWLGIHFPKWLK
NDLXYSEDIXGASIDTCVRTFKELLNYSLKKGIPIGVNVESVSIRKDEIDASIELLENVK
HLINKSL
>A0A223S5G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis gilva YIM 90087|TrEMBL
MTRSGTAPRPTPRPRDIRDLLNAGEPTFSFEFFPPKNPEGQRKLWRVIRELEALAPSFIS
VTYGAGGGTRDRTVEITERVATDTTLLPVAHMTAVDHSVRELRHLIGRFADAGVSNMLAL
RGDPPGDPLGEWVKHPEGLMYADELVRLLKETGDFSVGVAAFPYKHPRSPDIESDVKYFV
RKCEAGADYAVTQMFFEADDYLRLRDRVAAKGCDVPIIPEIMPVVKLSTIERSEQLSGAP
FPRHLAEEFEKVGDDKEAVRRLGIEQAQRLCERLLNEGAPGIHFITFNQSTATREIYREI
APHRVPAGGDARP
>A0A1T4WLG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmiger formicilis|TrEMBL
MTITEQFKAKRCVFSIECFPPKQTTQMDKLKDTLRQMQAMDPGFISVTFGAGGSAGGVST
AEVADYIQNELHIPTLAHLICMGNDETRAAEILDQLESVGVRDVLALRGDRSPSRPESPD
FKHASDLTSFKWKKPEFSVHGACYPEGHPEADSLLHDVENLRIKQAAGAEHLLTQLFFDN
MHFYRFLNLARRAGITLPVSAGVMPIVKRSQIERTVSLSSASLPSEFTRMISRYQDDPAS
LYDAGIDYAVRQLRDLIEGGADGIHLYAMNDAAVAAKVYDGIRDLL
>A0A5C4RT09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenimonas terrae|TrEMBL
MPRISFEFYPPKTDEQRAQLDRTVRKLKAHSPEFVSVTFGAGGSTLSYTAETVRGLREAH
GLNGVPHLSCVGGTRDEIRQLLADYRALGCDRIVALRGDLPSGMARAGDLHYASDLVRFI
REEHGDHFHIEVGCYPETHPQSEDALACIRHFKAKVDAGADSAITQYFFNADAYFRFVED
VRKAGITLPIIPGIMPISNFSQLRRFSEACGAEIPRWIGKRMLAFGDDADSVREFAADIV
AGMCRRLLDGGVPELHFYTLNLARPTESVLARLG
>A0A2G9XLZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium CG23_combo_of_CG06-09_8_20_14_all_48_27|TrEMBL
MLTSECGPPRGADAEVIRKKGNILKGVVDAVNVTDNQTSVVRMSSFSSCIILKEMGFDPI
LQMVCRDRNRIAIQSDILGAGALGINNILCLSGDHQKFGDHPMAKNVFDMDSIQLIHTVK
TMRDDGKFLGGEEVKGRPVLFIGAAENPFADPFEIRAARLGKKVKAGCEFIQTQCIYNIE
KFARWMEMVRERGLHERCAILAGVTPFKSVGMAKYMKNSVPGMDVPDAMIERMRGVPKER
QSEEGIKMCVETIQKLREIPGVRGIH
>A8GL87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia proteamaculans (strain 568)|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGSGKPDMYATDLVALLKDVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAA
>A0A4R8MZT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira meyeri|TrEMBL
MHISQILGKKQTTISFEFFPPKNAEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEGTGLTIVSHLTCVGSTKDEIREILKRYQKSGIHNIMALRGDPPKGQAEFHKT
ENGFEFAGELVGFIKKEFPEMGIGVAGFPEGHPSTPNRLKEIEYLKWKVDQGVDYICTQL
FFNNNVFYDFVERCEIAGIKVPIIAGIMPITSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDVYAENVGIHWATEQVRDLLDHKVAGIHMYTLNKSKATRRIYESLGIRNFDSIG
>Q5YZ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia farcinica (strain IFM 10152)|TrEMBL
MTFDPAPPHAAGTPSVVQSLRAHAGRSVPFSVEFNPPRDAAGEARLWRAVREFERMHPAF
VSMTYGAGGSTKDRTVRVTGQLAQETTLLPVAHLTAVGHSVAELRSLVGAYADSGIRNIL
VLRGDPPGDPLGEWHKHPEGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLATDTAF
LAAKLRAGAEYSITQMFFEVEHYLRLRDRLAALDPVEGAKPIIPELMPITSLRTVTRAEE
LCGRPLPAAVLDRLRRAAGDGPEEDRAAVREVGIEIATEMAQRLIDEGAPCLHFITLNFA
KATSEVLTNLGYGVTAAPVRA
>A0A4Z1P3Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Venturia nashicola|TrEMBL
MEKITDKLAALPEDGTYFSLEFFPPKTTAGFANLQARLERMSRALRPFFVNITWGAGGST
ATKSLELAELVQRQLGLTTCLHLTCTNMNKSLIDSALERAKAIGVRNILALRGDPPRNEE
YFNKEDLDEESTEFVWAVDLVKYIRKQYGDYFCIGVAAYPEGHSDQSHPDDQDPKHDLPY
LIEKTKAGADFLMTQLFFDVKAYEKFEDMLRDDPSGVFKTIPIVPGLMPIQSYQILRRTT
KLSHARLPPDILERLDAVKGDDEAVKAVGVDIISEIIEELQSRPYVGPRGFHFYTLNLEK
AVSQIVERCHLIPDLSAIDDDDDSALEISDDVSGLDGQPRRQRLSSVHSDPRNKVISDRP
SGNLNPEYETMEKDAGLPVDGATRATTLQISEGEGSLGREATWDDFPNGRWGDARSPAFG
EIDGYGPSLHVSTPQALKLWGHPVTVDDVSSVFSRHIAGELEAVPWSEDGLNPETATIRE
ELLKLNARGWWSVASQPAVNGIKSADEIFGWGPRNGFVFQKPFVEIFLPAADWTKLKRKF
EAYPEEITFFAANAAGDFESTDTRSVNPVTWGTFPGKEIVTPTIIEAVSFRAWAEEAFSI
WREWQHIYPPRSATAKLLGGIREGYWLVNIIHHAFIEQDGLWKLLLE
>A0A517TNQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium MalM25|TrEMBL
MRLPEIYATDRFALSFELFPPKTEAGVETLFRHAETLVEFDPAYITCTYGAGGSTQDRTL
EIAARVRREFDLPVATHLTCVGRTADQIRDYLRRAVEADVMNVVALRGDPPAGETEFKAT
EGGYSYANELVAMIRSDFPQMGVAVAGYPEVHQEAPSPEADLENLKRKVDTGADAIITQL
FYDNDDFFRFRDRCEAAGITVPLIPGLLPVTNASQIKRIVSLCGAKLPADFLAQLEACGD
DKEAQFRLGVEQATAQTQQLIDGIVPGIHYYVLNKSEATSQVLKSVTLSA
>F4G644|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicycliphilus denitrificans (strain DSM 14773 / CIP 107495 / K601)|TrEMBL
MSLPVSFEFFPPKTPEGADKLRAVRRQLYARAPQFCSVTYGAGGSTQEGTFATVRAIIEE
GVDAASHFSCIGATKAGVRQQLAELKAMGVKRLVALRGDLPSGYGLGGEFQYASDLVAFI
RQETGRDFHIEVAAYPEMHPQARSPEADLQAFATKVRAGADSAITQYFFNADAYSRFVDD
ARRLGVEIPIVPGIMPITGSSQLMRFSDACGAEIPRWIRLRLQGFGDDMASIRAFGLDVV
GRLCEQLVRAGAPGLHFYTMNQSAATLALCERIGC
>A0A5U8STW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Chester|TrEMBL
MSFLHIDQHEALNQNLAELAGRVAVSFEFFPPGTPEMEKTLWQSIERLSVLKPKFVSVTY
GANSGERDRTHSVIKSIKEKTGLIAVPHLTCIDATRDELKTIARDYWDNGIRHIVALRGD
LPDSSSKPDMYAADLVGLLKSVADFDISVAAYPEVHPEARSAQSDLINLKKKIDAGADRA
ITQFFFDVSTYLRFRDRCAAAGIDVEIVPGILPVSNFKQLQRFAGMTNVRIPGWLGTMFE
GLDDDPESRKLVGASVAMEMVKLLSREGVKDFHFYTLNRAELTYAICHTLGVRPAACVA
>A0A368W5Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus prosopidis|TrEMBL
MKPDLREALQKRILTGDGAMGTYLYQMGFPVGVSYEEFNTLRPDVIENVHRRYYEAGARV
IETNTFSANLEKLSKYGLENDMDAINRAGVRVARAAVGVDAYVVGAVGSIRDGKLKNLRT
AKVSEAYERQMHALLDEGADGLLLETFYDLDEMLLALRIARSASNLPVICQFAVEDVGRT
QDGIGLKEAFDQLQAAGADVVGFNCRSGPNGIMRAIDSITGPVGLPLSVYPNAGIPDYVD
GKYTYSAGPQYFAETALRFADRGARIIGGCCGTTPEHVAAMAAALDGYVPQSGQAAVAVK
SAETIEVQPTLKQAEPAVAVANLEPPANREPSIVELVQKRHTVIVELDPPRDLDIRKFMD
GAAALKAAKADAVTMADNSLAVTRMSNLALAALVQERIGLRPLVHIACRDRNLIGTQSHM
MGLDALDIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGTAFSGKPLKQKA
KFVVGAAFNPNVKHLDKAIQRLERKITSGADYIMTQPVYDPSLIERIAESTKHLSVPVFI
GIMPLASGRNAEYLHNEVPGIQLSDEVRQRMAGLEGEAGRAVGVQIAKELLDAALPHFKG
IYLITPFMFYDMGVQLTKYVWENTKRK
>A0A852YW80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora biskrensis|TrEMBL
MTRVVDRLQPGRTVFSVEFFPPRNDDEEQILWKAVRELEPLDPAYVSVTYGAGGSSRDRT
IRTVGRIARETTMLPMAHLTGVDHSKDELRHVVGSLADEGIRNILAIRGDPPGDPMGQWI
PHPDGILYADELVSLIRSCGDFSVGVAAFPHMHPRSADLETETDHLVGKIRAGSEFAVAQ
LFLQPEYFLRLRDRLAARDCHVPLLPGVMPITTPKVLSKFQHLAGVPVPPEVSAVLDPLE
DDPKAFRAAGIDLTTKLCERLISEGVPGLHFYSLNRAKATRDVVDNLGLAEGVLQPA
>A0A7M7H8P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nasonia vitripennis|TrEMBL
MYLRRVCRLASVGRVSRRSLDSSRGMRHRVLGDEEPQVDESESVLASATTLDPGPPVNLA
GLIREKIERRESFCSYELFPTKCHGVYQGRRGRRRDACRDTQICEPLFYALTWHEGWATG
EERFPSLKSAEVFPRNTLLHCTAKGLKKTDAEMILTRALELGIANIFALQGDSGSDDGDF
DHASDLVKFIRERYGQQFSICVAGYPEMHPHSPSKELDIFYLKAKVDAGADFILTQFFFE
SQLFIKFVNDCREVGISVPIIPGIYPFTDVKLLGKMIEICHTNIPDWIQEELRHIEDDDE
AVRKFGIDLSVKLIKEIRESAHFCGYHVYTLNRSFSAIEVHRQLNTQHEIDQLVASNS
>A0A2N3F6S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium HGW-Actinobacteria-7|TrEMBL
MSLREALEAGRFAVTSEVGPPKGIDVSAMMASAELLRGRVDALNVTDNQAAVMRLSTIAA
CVHLKQAGFEPVLQVTGRDRNRLAIQSDLLGAASLGITTVLALTGDHVVVGDHREAKAVF
DLESVQILKVIADLNAGHDMTGHDLIGTPEFYPGAVVTPGSVPLEPQIAKFEKKIAAGAR
YFQTQAVFDIEAFAHFMSGARESGAKVLAGVVVLRSARMAHFMNKNIPGIAVPDGIIATL
ERSENPQQTGIEIAARFIDECKEVCDGVHIMAVGAEHLVPQILDAAGLTEVIA
>A0A067KCG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jatropha curcas|TrEMBL
MKVIDKINAAQAVANGGGEANNRVVFSFEFFPPKTEDGVDNLFDRMDRMVAHNPSFCDIT
WGAGGSTADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRG
DPPHGQDKFVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDMIGSDGLATPENY
QKDLEYLKRKVDAGADLIVTQLFYDTDVFLKFVNDCRQIGINCPIVPGIMPINNYKGFIR
MTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKS
ALAILLNLGLIEESKIRRPLPWRPPTNVFRVKEDVRPIFWANRPKSYIARTLGWEQYPHG
RWGDSNNPSYGALTDYQFMRPRARDKKLHDEWAVPLNSIEDICEKFKKFCLGKMKSSPWS
ELDGLQPETKIINEQLGKINMKGFLTINSQPAVNGEKSDSLTVGWGGPGGYVYQKAYLEF
FCSPIKLQDLVNKSKAWPQLTYMAVDRAGTVVSNVGPNDVNAVTWGVFPAKQIIQPTVVD
PASFNVWKDEAFEIWSRGWASLYPEGDPSRKLLEEVQDNYFLVSLVDNDYIHGDIFAIFA
DL
>A0A3M8QR89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus sulfuriphilus|TrEMBL
MAHSVEFFPPKNAAGEARLREAIAALLPLGPEYASVTFGAGGSTRERTFATVEMILRDYP
LEAVPHLSCIGSTPEGIREILERYRQQGVKRIVALRGDLPAGMDNPGSFQHASELVAFIR
AFGGFEIFVAGYPEVHPQAPSALLGIEHLVAKVQAGANAIITQYFFNPDAYAQLRDDLER
RDVAVPIIPGIMPIVNYEQIARFSAQCGAEIPRYVRLRMEAYGDDLAAQMEYGIELLSRQ
CETILAQGAPDLHFYTLNQAEPTASIWRNLHL
>A0A0V1H159|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella zimbabwensis|TrEMBL
LMASLDAVELKTTRHDLNSSPKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTPEGL
INLLNRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCVLNFCLLDTMLHITSVQY
NEKTVLSNLERVKKIGIRNILALRGDISDDANVTATDFQYACQLVQFIRSHYGDYFTICV
AGLYLCAKVDAGADFIITQLFFNEMHYFQFVSDCRKIGIVVPIIPGILPIQSYQSIMKIV
QLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVELCRKLLNAEQHVVPGLHFYTLNQEK
SILEQIGLWKKAPGRILPWKKHPVHSVRCREAVRPIYWNARPKSYLCRTRDWKQFPHSRW
GDLGNPAFGDLKHYLFSCIDQMNDSRALDMWDKELSSFKHVRDIFCNFIARTPNRHGHTV
RRLPWNENHLDPAVDILKDELIYYNSNGILTINCQAAVNGLPSNDPTFGWGEANGYIYQK
GYLEFFASSKCTTILLNHVQNFPSVNYHAINFDGSFETLNYDEDATMALTWGVFVGQEIL
QPIVANAASFRVWKDEAFDLWQRWARLYESGSIGRKLLQSIHDDHRLITLIDNDYPQPCS
LSALLRAVISEYCEEKN
>A0A349GSD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacteriaceae bacterium|TrEMBL
GAFYPEVHFENNDLLDLFHLKTKVDSGTDFLVSQLFFDNEDFYKFKEKTQKLNINVPLVA
GILPVTNYKQIQKVRELCNAKIPRKFQTILDKFKDDPKALEEAGIIYATEQIIDLIASGV
DGVHIYTMNKVHVTRKILENIKYIREGIKEAK
>A0A840CA73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actibacterium naphthalenivorans|TrEMBL
MALLQFNSRATRRATETAQIEAFLKGFSIEVMPRTAEKIEDFRALLPERTRVYIAHIDGT
PIEDMVATAKRLAGDGFCVMPHVPARLVADAPMLADWIARYQGEAGVDQALLLAGGLAAP
RGAFENSMQLLETGLFDKAGFRRLHVAGHPEGSRDIDPDGSDRNVMQALRWKQAFAERTD
AEMAIATQFCFEAAPVIAWAERLRAEGIRLPIHIGVAGPAKLQTLIRFAVSCGVGPSLKV
LQKRAKDVTRLVVPFEPTDFIAELAAQKARHPAFNIEAVHFFPLGGIRASANWAVEHAAR
PADQT
>K2JST1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Celeribacter baekdonensis B30|TrEMBL
MTQAPNISFEFFPPKNIEACFSLFETVQALEHMQPGFVSVTYGAGGTTRELTHDAVALLN
RKYGWNVAAHLTCVNATREETLEIAKSYKSVGVNEIVALRGDPPKGAGQFTPAPGGFANS
VELIEALAATGNFKIRVGAYPDPHPDAADDSADIIWLKEKFKAGADSAITQFFFDADTFF
RFRDRCAKEGITGTIIPGILPITSWKGVQKFAAACGTPLPAQYAKAFETAEDQQAVSIEL
CTKLCETLTQGGVEDLHFYTLNRPTLTKAVCANLGVNG
>A0A7W7KBE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium chloroacetimidivorans|TrEMBL
MSDVIDAERAAPASSPAAGVSPFAELPGDIAVSFEFFPPKTEKMDAQLWDAITQLAPLSP
SFVSVTYGAGGSTRERTHATVARIARETDLRPAAHLTCVAASKAEIAEVADQYWQAGVRH
IVALRGDPPPADGGTFVPHPEGYASAADLVAGLKAQHDFEISVAAYPEVHPEALSDQHDL
DNLKRKLDAGATRAITQFFYSTDAYFRFLDKVLAAGIDAPILPGIMPVTNFAAIRRMSGN
TEIPGWLETMFEGLDERPGPRALVAAVAAADLCRRLYEGGVRDFHFYTLNRAEQAYAVCQ
LLGVRPKEA
>K1SQC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|human gut metagenome|TrEMBL
GGWSKYDIEDSLIDMDFLGLHNVLALRGDKRQNEPRFVPYAQGHAHAADLVRQIQAMNRG
EFIDGEVEECHHSKFSVGVAGYPEKHFEAANAQSDLQYLKEKVDAGADYIVTQMFFDNSK
YFDFVERCRKAGITVPIIPGIKPISTPKHLEILPRTFSVSLPEELVKAVRACGEDTQAAR
EVGIEWAIHQAKELKAAEVPIIHFYTMGRTDNIRKIARNVF
>A0A6I1GP80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium cebidarum|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGIEDLKPDFISVTYGHGTHSDRTATARIANTIV
NEYRIPAVAHLTALYSDKAKIDEALDMFENAGVNTVLALRGDYIDGEQVVGTFEHASDLV
AYIRERKPNFTVFGACYPEGHYQAESLDKDIEHLRIKVDAGVTHLITQLFYDNDDFYRFR
DKVRAAGIEVPIEAGIMPVRGAKSVRRMAERNASRIPEHLDALLTRWEGNSEALHNAGIL
YASEQIADLVAHGVDGVHLYTMNHPATTRRIWRNVKSLFGE
>A0A8H2X0T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MPPFTRSVTKARLRDVSTPPRTYADRVLTQMQRDSLWDPKAPPRKFSDARGLKDLIEIAV
VFVVATVLDIVKDIVMISKKPIGWLLAAYLILMALSGTSDLFVKTFMSPVCKLPLISGRI
DYCTRDAFSRRFSPDFPKLASLQSRLEDVMDDSASSSIVAVDIKNSEMAVRDLTTLVKLS
SLVAKDALVDRLNEFVVDAKAAGRNLQRFGGRVGGAVDQIVTMNEYVLKLLENTVKDSQP
QISGGTVQRVMNAVSPIKTAGPQVIAARRKEVETMWYQATGMMESTIRKLILEAEVNIVG
LDKLEGDLDLINEMILREDEGIRAQAEEVMILREDEGIRAQAEEVLGELWTKLGGNKKKL
NNFRSHRMLLNEIRIYRKRALAHVSSTLVQLQGLSADLDDLSHRMLLNEIRIYRKRALAH
VSSTLVQLQGLSADLDDLRQRVATPALAGEEAGIPLEVHIGSMQKGTERLLEGRKRARER
EDAYLQKTPIIAMKVTEKIQQAEKDNRIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEF
VDITWNAGGRTSDLTSELVKTCQGMIGIETCMHLTCTNMHQEKVDVALREAKANGCRNIL
ALRGDPPSGQEEWTSVEGGFQHGIDLVKHIRRGYGDYFDIAVAGFPQTIQLPEAEAKQEM
QWLKEKCDAGANFIFTQMFYDPDMFIRWVKAAREAGITIPIVPGINPIQTWNGFIRATSL
SGTDIPQDLMDILEPHKNNDEKVRELGTKIVADLCRKILDADIGIKGLHFYTMNLEKGTK
MLLEELNLVPRVETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWDEYPNGRF
GDSRSPAYGELDGYGIWIKQTPEEGRKIWGTPTTIDDVKALFAKFCSQEIKALPWSDQPP
STEMLVIGQQLMRMNQLGYLTINSQPAVNGARSDDKAFGWGPKNGYVYQKAYLEFFVRPD
QLQTLIKRIERDTNVTYYAINKQGDLKTNSTSDGPNAVTWGVFPGKEVVQPTIVEAVSFM
AWKDEAFELGCQWAKIYEPGSPSRKLIEDMMDEYFLVNLVHNDFHDREAIFRPFFADNGL
KVNGDTEIPVTNGVKQVNGLVNGHSTAVRA
>A0A2U1DS10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. 99|TrEMBL
MNAAHAQGTGFPVSFEFFPPKTPEGADKLRVARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILSEGVGAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPDADLQAYVTKVRAGADSAITQYFYNSD
AYFRFVEDAHRLGADVPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASI
KAFGLDVVTDLCDQLRTAGVPALHFYTMNQSAATLEICRRLGI
>A0A0N0KGB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. AAP83|TrEMBL
MNASYDQLREARTALDTPLFAGLPGDINVSFEFFPPKTDALMAQLWDVVETLAPLEPHFV
SVTYGAGGSTRDRTHGTVARIIKDAKLPAAAHLTCVDATKAEIREVAESYWEAGVRHIVA
LRGDMGAPGVPFTPHPEGYANAAELVAGLKTIAPFEISVAAYPESHPDSPSQQADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAAACGAA
IPAWMDGLFEGLDTHPGSRQLVAATISAEFCRRLYAGGVRDFHFYTLNRAELSYAICRLL
GLRPTRPALEKAA
>A0A4U1CV39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter polaris|TrEMBL
MKITEHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADSSFIPTKGGHCYATDLIQHIKNHNDGKFLHEDIETFKSDFCIGVAGYP
EKHFEAPNLNADFKFLKQKVDMGAEFIVTQMFFDNQKYFDFVNKCRENGINVPIIPGLKP
ISTLTQLTVLPKIFHIDLPDDLTDALSHAKNNAEAKEIGTAAMIKQCKELIEFGAPVLHF
YTMGKPEQTKQIARAIF
>A0A1Q4WCX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02056|TrEMBL
MRDILAAGERTYSFEFFPAKDEAGERALWAAIRRVEAVAPTFVSVTYGAGGSSRDRTIGT
TELIAAQTTLRPVAHLTAVGHSTAELQAVLRRYADVGIRDVLALRGDPPGNPNGRWEPHP
QGLRYAAELVRLVKECGAFTVGVAAFPERHPRSADWDDDIRHFVAKCRAGADYAVTQMFF
DVEHYLRLRDRLAAAGCATPVIPEIMPATDVRQIRRFAELSGASFPAGLARQLEAARGDR
ATAHRIGVDHATRMAERLLLEGAPGLHYITLNRSTAALEIHRNLALTTPTPRALTPTAA
>J7R7R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / KCTC 17520 / NBRC 10181 / NCYC 3082 / Yp74L-3)|TrEMBL
MKITDKLHSYHELSGKPTFSFEYFVPKTEQGVQNLYDRMDRMYEASLPQFVDITWNAGGG
SNSTNRGITQQSTDLVATAQSVLGLETCMHLTCTNMPVQQIDNALESAFQSGCQNLLALR
GDPPRGPLGGGDGDEWQPVEGGFRHASDLVRYIRAKYGDHFNIGVAGYPEGHPEEKNPEN
NLLYLREKVDAGADFIITQMFYDAGRFVEWCRQVRQAGVEVPIIPGIMPITTFAAFLRRA
SWGSVHIPQRFLDVLTPIKDDDELVREMGTALVVQMCQTVLDSGYVNHLHIYTMNLEKAP
LMILERLRLLPTDAELVGTGASLLPWRKSLNPNRRREEVRPIFWKKRPYSYVARTSQWAE
DEFPNGRFGDSSSPAFGDLDLCGSSLIRQSRKRALELWSTPRTLNDLGQLVNNYLTGKIV
CLPWSDTPLDHEVDTMLTRLLHLNSNGIFTINSQPQINGVRSNDKIHGWGPRDGYVYQKQ
YLEFLLPRGKLASLQSRLQGNEIMTYFAIDRRDDLVSNHPDGSRANAVTWGIFPGREVLQ
PTIVERVSFLAWKEEFYRILEEWKLLLKENNENESASLIDTIINEYYLINIVDNDYISQE
DNIYNLLTTL
>A0A7Z9WX86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MLVKDLLKSHKTTFSFEFFPPKEDAAADRLLNTISNLMPLGPSYVSVTYGAGGTTRDRTH
DLVVRIKKQTDITVVSHLTCVGSSRSEMHSILEKYQEAGIENILALRGDPPKDMKNFVEP
EDGFAYAADLVEYIKKHFPEMCVGVAGFPEGHPATPNRLQEIDYLKEKVDAGADYIVTQL
FFKNSDFYDYCERCELAGIKVPNIAGIMPVSTKHGLIRTAELAGGARIPARLLKAVYRAE
NDEYVEKVGIHWATEQIRDLIDNDVRGIQFFTLNSSLATQEIYNSLGVRDSTQLR
>A0A7C0YED0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MSEYKSESNLEKVLKAGHFAFTGECGPPEGADVEQLRKKASYLKGCVDAVNVTDNQTAVV
RMSSWAASLILLQEGLEPNFQMVCRDRNRLAMQSDILGVYAHGIRNMLCLSGDHQSFGDH
PEAKNVFDLDSIQLIYTVKTMRDEGKFLSGKEIKVPPKLFIGAAANPFAEPFDFRVRRLA
KKIAAGADFIQTQCIYNMEKFREFMKRVVDMGLHEKCYILAGITPLKSVGMAKYMASKVP
GMDVPKSLIDRLKGAGKGKAAEEGIRIALEQIEELKEMEGVSGVHLMAIEWEHKVPEIAE
RAGMLPRPQVN
>A0A752ITR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. houtenae serovar 21:z4,z23:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4W5N9H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hucho hucho|TrEMBL
TATHASLYSAVFAFYESLGLGRSPLDDTWRTCTKSDSSGTSSGGESSKESSRSSTPVLDA
DRMDRLRDKMRRRTESGDHWFSLEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAG
DPGSDKETSSMMIASTAVNYCGLESILHLTCCNQTKDKITGYLSKAKRLGLKNIMALRGD
PVGADWEEEEGGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVD
AGADFIITQLFFRADTFLKFVRDCRAIGITCPILPGIFPIQGYQSLKQLVKLSKLEVPEE
IMRVIEPIKDNDAAIRNYGIEQTVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLW
IEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGE
LNDYYLFYLKSKSSKDALLKMWGEELTSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDEP
LAPETNLLMDELDKVNRRGVLTINSQPTINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSS
ENITVLLKVLKKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVS
FMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDM
FELLDNPPEEQPTEQPAEQPAEESPVEDQPPK
>A0A2U3LWP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfosporosinus infrequens|TrEMBL
MTVEIERMKKKVEMGADFFQTQPIYDIAKAREFLEQAKALGKPVLLGIMPLTDLKLVKFI
NNKMAGVTVTAEIIKQMENGKTGIEIAFEFIAELIEDIAGIHIYGMGDIQTTNKLIKFTK
SLMNK
>A0A836NXP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. syringae FF5|TrEMBL
DLKHFVNKANAGADSAITQYFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFS
DACGAEIPRWIRKQLEAYGDDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSL
AVWNNLQLPR
>A0A2G4KH33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. BP25|TrEMBL
MTLPPTRRVIGPVARAGERTGRPRVSFEFFPPKTPQMEESLWQAITRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRAEVDEVIRDYWETGVRHIVSLRGD
PPPGEGGIGGVYVPREDGYANATELTKAIRGVAPFEVLVGVYPEKHPESPSLEHDIDVLK
QKVDAGATLGISQFFFDLDAFLRYVDKVRAAGITIPIVPGIMPVTNFAGLKKMAAACQTT
IPGWLANLFDGLENDAETRRLIACSVATEMCAKLQEQGFEDFHFYTLNRADLVYAICRVL
GLREVPPSASEVAA
>W5Y2T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium vitaeruminis DSM 20294|TrEMBL
MAQQPIPASYQRSITDVISMPSPGRIPFSVEFMPPRDDAAEARLWKAAETFHDLGAAFVS
VTYGAGGSSRERTTRVARQLARHPLTTLVHLTLVNHTEEELISILKDYAGAGLSNLLALR
GDPPGGDPLGEWTPTPGGYHFASELIELTKRLPETSHFQVGIATFPEGHFRAPSLEADTE
FTLAKLRAGAEFSITQMFFDVDYYLRLRDRLVKADSEQGAKPIIPGIMPITSLRSVRRQI
ELSGAHLPAQLEERLVAAARGDEEAHRDDIRKVGIEVSTAMAERLIAEGVPDLHFMTMNF
ARATQEVLHNLGMAPAWGPELGHDAVR
>A0A4Q8L0X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasuis|TrEMBL
MIGQTPSLSFEIFPSKPEVGNEKIIHALNEMQGLAPHFISVTCSKNNLNVEETTVKLANH
VHNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIINELSPKEDFKYATD
LVSFIKEEAPQFDIIGACYPEGHPESPNAVSDIKNLKKKVDAGCSTLVSQLFFDNEAFYN
FQEKCILADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHDPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARTIHEATHALFKHYS
>A0A1W9G5L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. HN-bin3|TrEMBL
MSREPQRLIEVLDRGTFAVTVEYNPPKGTNISSVLENAKQLVGRVHGVNITDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNSGKDMMGNRLDGSTAFTIGAAVTPEADLVGPVLAKFEVKV
KAGAQFFQTQAVYNPDVFAGFMKQVRPFKVKVLAGILVLRNHKMAEFMNANIPGMSVPKE
MIDELKAAGDRAEDVGVDIAVRSIKAVRPHCDGVHIMAIKATHRLAEIITKAELG
>A0A066XNQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum sublineola|TrEMBL
MHIKSMLEETRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLDKVNDALRKAYKAGCTNILALRGDPPREHEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGKVRERGITVPIIPGIMPIATYSSFLRRAKHMNCKIPEAWMAAL
EPIKNDDVAVREVGKGLVADMCRKIVAAGIHHLHFYTMNLAQATRMVLEELNWMPTSDRP
VKHALPWKQSLAHGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSIRDIAAIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSNHPVHGWGPANGYVYQKAYLELLVHPDMYAEIVSRIEKNP
DITYYATTKNGNLKYNATNDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGIDW
AHCFEAGTPSRVLIERIMNEWYLINIVNNDFHQKTALFDLLEGLEVKEYTDIPAEPQTNG
AAKEQAAVANGNSVSVTAN
>A0A1G3MDN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium GWB1_66_5|TrEMBL
MPGRGYTGVGIDNILKFAQEARDSRHVYGLSITDNAGGNPALWPDVLVPEIAAIGCDLMV
HFSCKDMNRNMIEARAYAMKRAGITNLLVITGDYPVTGFFGQPKPVFDIDSVTALHYLQE
MNRGLKAGTAAKSLRLEPTDFLLGAVASPFKATEASAVMQYIKLEKKLRAGAHFIVTQLG
YDARRSAEFIRYVRQILRSNIPVMGSVYVLSAGAGRFMNRGEVPGCYVDDRLVADLTGEA
GAPDKGKGARLQRAARQVAILKGLGYNGAHVEGLNLKFGDVTEILQRAEAIGDNWRDHVE
SFDYSPAGSFFLFEGSDTFDFVKNPSAAPLRQTRRPGIASPVFWAMRILHNLVF
>A0A260QLK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 15-649-2-2|TrEMBL
MSEEPVRGRASRGFVTNTPSIVDRLRTEPDARIPFSVEFSPPRDAAAEARLWRAVREFEQ
LAPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRG
ITNILVLRGDPPGDPLGDWEKHPDGVEYAEELVRLVRDLGDFHVGVASFPEGHHRADDLE
QDTRCLVGKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDAEQGAKPIIPEIMPITSLRSV
RRMLELSGTTLPSSLDEKFTRAAGSGPEEDRAAVREVGIELATNIGERLISEGAPGLHFI
TLNFARATREVLCNLGLAPARV
>A0A1G1P498|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium RIFCSPHIGHO2_02_FULL_50_17|TrEMBL
MKKIKDIFREKGKTFSFELFPPKTEEGFRNLLNTIDGLCALEPDFISCTYGAGGGGREKT
LDVVQHIQDKHAVAGLAHLTCVLHTKEEIKNILKDIQSRGIRNVLALRGDPPQDNPRWKP
GEDSFRYSCELCTFIRQNFGDYFTIGVAGFPEGHILCPDRALDARYLKIKIDNGADFVIT
QLFFDNKDYFDYVARLRSLGVTNRVIPGILPITHYKNLVKFCALCGATITPEVKEIFEPI
QDDQERTLKAGIDFAVRQCRELLDGGAPGLHFYCLNKISPTDKILSEIRR
>A0A255TAG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. P2-180|TrEMBL
MTVIELINNDKQKRHFSFEVLPPLKGTGTEKLFATIDKLKEFNPLFINITTHHSEFVYKQ
MDNGLLQRQRIRRRPGTIAIAAAIQNKYGIPVQPHIICSGATIEDIEYELLDLQFLGISN
LLLLRGDKAKEDPRFIPTKGGHEHTTDLIRQVNRFNEGFFADDTPVKCPGEKFDYGVACY
PEKHEEAPNLEMDILHLKEKQDLGADYAVTQLFYDNSKFFAFLEKARQMGVTMPIIPGIK
PFAKLSQLSVVPKTFHCDIPQELALEAVKCKTDEEARQLGVEWSVAQCKELYAHGINNIH
FYTVSAVDSVAEVAGRLL
>A0A6H8JR03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIASILQECKERQLDKILALRGDVCNDLGKSKDFSYASDLISF
IQKQGKFEIYAACYPEKHNESRNFIEDIHHLKNKVNAGTDKLITQLFYNNEDFYTFKQNC
ALANINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAV
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEEIRA
>A0A7V4P3M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MRIRELLSTGRPSFSFEFFPPKTDEGLVSLKQTVLSLRELRPTYVSVTYGAGGSTRDRTV
DLVTQIQREHPFEAMAHLTCVGSSRDDLRQVLDRLAAGGVENVLALRGDPPRGATSFVPA
ADGFAYSSELAGFIRKHYSFCLGGACYPEVHPECVDGSGRRDARRDLENLKRKIDAGVEF
LVSQLFFDNNVYFDFVARARAAGIGVPIIPGIMPITNVDQVKRFTTMCGASIPTHLLDEL
ERLKDNEDAVLSLGVAYATAQCLDLLQKGVPGIHFYTLNKSAATRTILTALQTIWPPAKE
PASGRSMQA
>A0A8I2C1G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. PvR133|TrEMBL
MKPDLRTVLNREIIVGDGAMGTFLYQLGFPVNTSFEELNITSPDVISDVHGQYLSAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
LELARNYEQQIDALLSEGVDGILCETFYSLDEIRIALHSVRKYSDIPVICQFAVDQVGRT
QDGFLVAEAFSVLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAKSFVDLGTRLLGGCCGTTPDHIAAISKALNRLQPPPLASKEALS
KESFQVAEQIADEGERGNGRHTSEPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHALK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYVMTQPVYDHELIAAIAEATRHLEVPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGPEGRAMGVSIAKELLDTAMEHFNGIYFMTP
FMFYEMTAELTSYVWQKSGRVQAPLFRL
>A0A7K2J7G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4944|TrEMBL
MALGTASTRTDHARTVRDMLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHRQS
>A0A7V1EJX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MSKPLSKLQESLGSGAFVVTGEIGPPKGTNIEPVLHEAEEYLKDNVVAVNVTDIQTAVMR
LGSLAVSHMLTDRSIEPVFQMVCRDRNRLALQSDLLSAYTLGIRNVLALTGDHVAMGDHH
EAKSVHDLDSVGLLETMVRLEAGSDLGMDMKGKPNQLDGAPEFFKGCCVTPCADEVEPQI
IKLEKKVAAGAQFVQTQAVYDPDSFEAFMKQIEHVKIPVLVGIVLLKSAGMAKYMNRSVP
GVKVPDATIQRLTDCAKEDRQKVSIEIAADLVRQMKPLCQGAHLMTLGWDNCVPAIVAQA
GLA
>D0LSQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)|TrEMBL
MSGTSCLKPFLEALAQGPLLFDGAMGSLLYDRGVFHTRNYDELSLSQPKLIRAVHREYLE
AGAQILETNTFGANRIKLTAHGHSERVADINRAAVEMARSVADDRAYVAGAVGPTGIRYT
IAPAAERKRAIEALGEQIDYLVEAGVDLLCLETFGAILELEAAIELARQIAPEMPVVAHL
VFDADGLVEGELDGATVAQRLIAAGANAVGANCGVGPPELYAVGTKMSDVGAPVSIQPNA
GFPSNIDGRTIYVANPEHFGVFARRMLKSGVRMVGGCCGTTPEHVRAMLGAVRMCGGADI
FRPASAPVTVSVRAATEPPVPREVVVPLAMRSRLGARLAAGQFAVSVELTAPAGTDDSKL
LGNIRTLLEAGVDVVNIADGPRASARTGNLAVCTKLQATTGVEPILHVCTRDRNYLGLIA
HLLGAHALGIRNMVIITGDPPKMGDYPFATPVYDVDSIGLLRMARTLNEGYDPAGKEIDG
HTSFVLATGAEPAATDYEREMRRLEDKRAAGAELVMTQPVYDPRVLERFLDDAEPLGLPV
MVGILPLASHRNAEFLHNEVPGMQIPQSYRDRMEKVGSGPEARAEGVRIAQEALEAVKHR
VAGVYIMPPFNRVSSAIEVLDVVRDRWQPAPLPAPGGPLRGPA
>A0A416EAC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF34-10BH|TrEMBL
MKIRDILNKDTATLSFEVFPPKKSTDFGNVEAAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGEIQKQHNVPTVAHLTCVCADRSSIGAALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKENGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIVPGIMPITRGVQVRNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHVHVYSMNKPDVAAGIQRNLSEILKA
>A0A0Q6AX25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf407|TrEMBL
MTPTISDMEEARRALDAPLFADLAGDCSVSFEFFPPKNEKMEAALWETVRALEPLAPKFV
SVTYGAGGSTRERTHATVERIARETSMPAAAHLTCVEASRAEIDEVAQAYWAAGVRHIVA
LRGDPPTMGQKFTAHPDGYENAAALVTGLQKLHPFEISVAAYPECHPDSEHQAADLDNLK
RKIDAGATRAITQFFFTPEAFFRFRDAAAAAGINADLVPGILPVSNVGQVRKFAGMCGAA
IPPWMDRLFEGLDDHPGARALVAATVAAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLM
GLRPKAMAIAAAA
>S2E0J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Indibacter alkaliphilus (strain CCUG 57479 / KCTC 22604 / LW1)|TrEMBL
MKITEYIQQAKKPLFSFEILPPLKGQSLNDLLEGISPLMEFEPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFQVEAVPHLLCGGFSKEETENALIDLNFIGVQNV
LALRGDAPKNEGKFVPEPNGHEFTTGLVKQIVGMNNGKYLHEETEASFHTDFCVGVAGYP
EKHFEAPSMRFDLKFLKEKIDAGAEYIVTQMFFDNEKYFDFVKKVRDAGINVPIIPGLKP
ITTLGQITMLPRTFFLDLPDPLLDELEKCKNNADVKQVGIEWAIQQSKELIANGAPVLHY
YTMSKADATYKIAKEVF
>A0A5C6IS79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces misionensis|TrEMBL
MTTFSFEFFPPSTAAGERALWNAVRKVEALRPDFVSVTYGAGGSSRDRTVALTRRIAAET
TLRPAAHLTAVGHSVAELRHIIGSYADAGIRDVLALRGDPPGDPQGPWVPHPDGFTHAYQ
LVELLRSLGDFTIGVAAFPEGHPRSPDARTDLRHFVAKCKAGADYAITQMFFRAEDYLRL
RDRVAAAGCETPIIPEIMPATDVRQIRRFAELSAATFPEDLAHRLEAARHDPAVAHRIGV
DHAVAMADRLLAEGAPGLHYITLNRSTAALDIHRTIHASRSLSVR
>A0A1U9JWB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Tokpelaia hoelldoblerii|TrEMBL
MSFLSRRNDIGEQLKVSFEFFPPKSEKMEEMLWQTVERLAPFAPEFVSVTYGAGGSTRER
TARTVARIIQETGLQTAAHLTCVDATREEVDKVVQEFSALGIRRFVALRGDPANGAGGVY
TPTPDGYFNAVELVAGLKAIDADFDITVAAYPEKHPESSDFATDIELLKRKIDNGATRAI
TQAFFDNDHYEGYLEKVRRAGIYIPVLPGILPIHNFWQVRNFCERNSTHIPDWLAHRFDG
LEDDWKTHGLVAAATAAEQVLDLMERGVTDFHFYTLNRADLVYAICHLIGIRPKPAA
>A0A2I7N9H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquella oligotrophica|TrEMBL
MRVSDHLSQAKKTLFSYEIVPPLRGSTPITEIFSIIEKLLPYDPKWINVTTHASSLLYVE
NSDGTISKRIHKKRPGTMGICGVIQNKYGIDAVAHVLCQGFSQQETEDALIELNYMGIEN
ILALKGDNLNYNRQIADNETVNRNAVDLVRQVAKMRDGKFIADTEYPPVDFCMGVAGYPE
KHFEAANMQLNIDYLKQKVAAGAEYVITQMFFDNDKYFAYVDACRAAGINVPIIPGIKVI
KTANQLNSLPRLFHIDLPHELVSELVAKPEHAATIGKEWAKTQVKDLIARGAPCVHFFLM
NDVSSVLEIIKDFN
>A0A4R3LY08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquabacter spiritensis|TrEMBL
MTSPIRPSRELGRAPVRVSFEFFPPKTEEMERTLWASIARLAPLGPSFVSVTYGAGGSTR
ERTHATVERLVRETALAPAAHLTCVAASRGEIDDVIREYAAAGVRHIVALRGDPTTGVGT
SYEPHPDGYAHACDLVAGIRRLGDFEVSVSAYPEKHPESESLAADIDFLKRKVDAGATRA
ITQFFFENDVFFRYLDAVRAAGIDIPIIPGILPVTNFKQASNFAARTGASVPSWLLKRFE
GLDDDAETRKLIAAAVAAEQVTDLVDRGVPDIHFYTLNRADLVYAICHLMGLRPRAEEAA
AQRLAV
>A0A4R0BAX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGVSIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFARFDD
KPEERAKVAADIAAEQIEDLVRRGIHEFHLYTMNRAPLVSAVLDNLGFCRRPAKSAGAAA
>A0A5Z1E0A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGKLSPNFISVTFGAGGSINSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYQAVKHLLKEELHA
>A0A2E2N550|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHIRDIFRTRRTTVSFEFFPPKTEQAAQDLYANIAELEELKPSFVSVTYGAGGSTRELTH
DLVTRLKRETTLDPTPHLTSVCHNEAEIGKILERYAEAGISNVLALRGDPPAGMDDYNPD
DDAFKYASNLVAFIRKFNDSGSHPDPKGFGIAVAGFPEGHPATPNRLNELDYLKAKVDTG
ADYIVTQLFFDNRDFYDFRERCELAGINIPIIAGIMPITSAKGMRRMGDLAAGARFPAPL
LRAIRRTGEDPEAVKRVGVHWATQQCFDLLDHGVSGIHLYTLNKSKGTQEIYKALGVSDS
RALTRS
>A0A1G0JT70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPLOWO2_02_FULL_52_10|TrEMBL
MACVSIYAXXXVPHIAARRIQSRGELQEFLDSAVRNFGVRRVLLIGGDIAEVMGPYNDAS
AVLKDGILEANGIREVGLAAYPEGHAHIRKERLHQILQDKLELAARIGLGTYILTQFSYI
PSRVVDFCAMLSRRFPETAVYVGIAGPTEPDKLVNYAKICGVSASIRALTDLGLKAAQVV
SHTDPGSQLETVARYCAAREACNVTGIHVFGFGGFIKSSQWMHRLYSK
>A0A7C5PQW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobium narugense|TrEMBL
MTLRIKERYKSEKTGFSLEFFPPKEVEQEKKFKETIKKYVDLKPLYASITYGAGGTTQDK
TFEIVEFINSLDVFAVMPHLTCIGATKSSINSLIKKYDELKVFNILALRGDPPKNVENFD
ISKGEFKHAIDLVKYVREYFDHFSIGVAFYPEGHSQARSFEEDFEHCIEKFKIADFAISQ
MFFDNAYFLRYRDLVIKRGVDITLVPGIIPIGNFERIKEFARFCKVTIPTKLEDIMSKVS
SSEDMKKAGIDWAIKQCSELIKEGVMFFHFYTLNQFELCSEVIKNFW
>A0A0D2ZVZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica oleracea var. oleracea|TrEMBL
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNAICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEADGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPVVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAYGIHFATEMCKKILAHGITTLHIYTLNVDKSAIGILMVV
PHFLKYDFLI
>A0A7G8FPS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. RS9907|TrEMBL
MSTALQRAIEAGDQVLTAEVMPPRGADPSHMLAMAASLQGRVHAVNVTDGSRAVMRMSSL
ASCRLLLEAGLEPVLQMACRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAGDQADARP
VNEFESVKLLQQVDSLNQGVDPVQGTLPDGATTLFAGCAADPQSRSWSGLQRRLQRKQAA
GARFVQTQMVMDPEALERFQREQAGPLGLPVLAGVFLLKSAKNARFINRVVPGACIPDAL
IHRLECAENPAMEGVAIAAEQVKRYLGIVRGVHLMAIKAEERIPMILDRAGLSSLPG
>A0A8C3AJB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclopterus lumpus|TrEMBL
MVNQVQRGDGSLRSCKSDSSGLSNSGGESSKESSRCSTPVLEADRSDRLRDKMRRRTESG
DRWFSLEFFPPRTASGAVNLISRFDRMSAGGPLFIDITWHPAGDPGSDKETSSMMIASTA
INYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEEGFNYAT
DLVKHIRSEFEDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITRVIEPIKDNDAAIRN
YGVQQAVEMCRVLLDSGKVPGLHFYTLNREVAIMEVLRQLGLWIEDPRRSLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSTKDA
LLQMWGAELMNEESVYEVFTCYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNK
RGVLTINSQPNINGKPSADPIAGWGPAGGYVFQKAYLEFFTSSENVTALLEVLKKYEPRV
NYHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWQVIDDMFKMLDAPPGVPPSSVSC
>A0A4S9C348|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATRSEMPSDRIVDKIAALPENSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSIANS
APQNRVVIDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVE
FFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWNEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLL
EA
>A0A4S9NFV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEVTAPEAPQ
KVSGATNGEKHEEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A4A9E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Congregibacter litoralis KT71|TrEMBL
MSKSAAISFEYFPAKTDAGREKLLNVTTPELQAVGPEFYSVTYGAGGSTRDNTRGIVEGL
NAQGLDVAPHLSFGLDDEATIAALLQDYKAAGIKRLVALRGDLPSGAGGGARLVYANELV
AFIREHTGNHFHIEVAAYPEIHPQAESYESDIHYLKGKFDAGADSAITQYFYNVEAYFYF
LDRCAAIGIDKPIYAGIMPITNYANLARFSKNCGAEIPRWISKRLEGFADDQESIRAFGI
DVVTQLCQTLLESDAPGIHFYTMNQAQPTLQICRNLGL
>A0A354HI52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKISELFKSGKPVLSFEVFPPKKDSSVESITAAIDELAQLRPAYISVTYGAGGNTANTFT
RDIAAHIKNDCGIEAMAHITCVNNSKEEVLTVMDSFAEAGIENILALRGDINPNVPPKTD
FRHASELITFIRSDPKYDNIGISGACYPEGHTEADSLTADILNLRKKVEAGAEELITQLF
FDNAFFYDFREKSVIAGINVPISAGIMPVTSKSQIERMVTMCGASLPQKF
>A0A098QYK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaeta lutea|TrEMBL
MVQLFQGCTEEGKTPFSFEFFPPKTPAGWEKLYATITQLLPLRPAYVSVTYGAGGGTRDN
THELVRRLNDQGVPVVAHLTCEGSSEPEIREILETYDREGIHNILALKGDVPMDRRTPGP
SFEYAADLVSYIRRRFPHFGIGVAGFPEGHPDCPNRLQEMDYLKAKVDAGADYVVTQLFF
DNRDFYDFRDRAELAGIQVPIIAGIMPITTRKGMARMAELAGGARFPAKLLKAVGRAADE
QGVARVGAHWATEQISDLLANHVAGVHLYTLNTSTSSLEILKNLGLTSYSIKSDV
>A0A164BN54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. MIT S9508|TrEMBL
MKGLGSALQRSLEAGAVTVTAEVMPPRGGDPSHTLAMANLLRDWVQAINVTDGSRAVMRM
SSLAVCRLLLDAGLEPVLQMAGRDRNRIGIQADLLGAHALGIRNLLCLTGDSVKAGDQPS
VRPVHELESVRLLQQVSAFNRGEDPVKESLPDGPTALFAGAAADPHCASWSGLKRRLERK
REAGARFVQTQMVMDPQVLERFCRDMAAPMELPVLAGVFLLKSARNASFINQKVPGANIP
DSLIARLDAASDPAAEGIAIAAEQVRQFAGIAQGVHVMAVRAEERIPEVLERAGLSSQQL
>A0A4R4Q1H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella albertanoniae|TrEMBL
MPGFELICEVEPPTRPDLKKVRHQIGVMSPIADAFLIPDNHIGRATVSSVAVANEVQAMG
SRGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDDPAEGARTSQLTVRAMIEQTRA
TTYPNLKPFQVGATTRLRPVPRWKAEADFLFVQISYDVDELLRWRDSVDLTIPVYAGVMV
LASPAMARNLAALPQLTIPDSLIKAVDQDRDAGVDHACEQIVRIRDSGAFDGVHLIPVSR
YRQVAARLERELHRG
>A0A4T0BCN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVNVTWGAGG
STSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILALRGDPPRS
DEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQSHPEHQHA
TYDLPFLVEKVEAGADFLMTQLFYDLHAYQDYEKLLRQHESGAFKTIPIIPGLMPIQSYQ
ILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSGPKGFHFY
TLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSIANSAPQNRVV
IDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIPWSEEGLN
PETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVEFFCSHED
WTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIEAVSFRAW
AEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLLEA
>A0A3D0KQ17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKVNSLFNKDKTVFSFEVFPPKKESPIESVYGKLEEICALKPDFVSVTYGAGGSGGHSRT
CEIASRIKNVYGVESMAHLTCVNSTKQLIDFMLGDFQAHGIENILALRGDRVPGVNPEND
FKYASDLTAYIRSRGDFDVCGACYPEVHVEAKDAVEDILNLRKKVDAGASHLITQLFFDN
SVFYDFRDRARIAGVNVPVEAGIMPVTNKKQIERMVYMCGASLPAKFSKTMQKYEDKPEA
LRDAGIAYAVEQIVDLISNGVDGIHLYTMNNPYIARKISEAVSSLL
>A0A351ECF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MRISDILKTNKVTVSCEMFPPKPGKPLENTQQVVHEIAAYKPSFMSVTYGAGGSNSKNTL
SIAEEVQKSGVTALAHLTCVGQDEENLRASINAFKASGIENI
>A0A7Z9ZNI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Peregrinibacteria bacterium|TrEMBL
KGRIDFLKNLQDEIKIPIIVGILPIKSWGVAKYMQENVQGITIPPADYKLFQYLPDAEIF
ERQVAQAQEIVRYAREKNLAGVHLMPLGRGDKIPEILGYNHEKGVFNFFEKPLYLH
>A0A7Y2I4J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp|TrEMBL
MFDFPYIIELLTPKKTDDQYPERLLNRFGERFNRAIESGCAVSIPDNPMGNLRMGALETI
EMLNLTFDPERLVINLNTFHLKDELDEILEGALQTGIRSLLVIRGDGGPDLSRLEPAHIG
GKFNVASSTDLIDYINRAYPGKFMTGAAFNHYNPIEVELKRLDKKIGAGAQFIVTQPVIG
NDSRLNQLTARDIPLVVEAWMSNNIELFSQSVGDDTLSIADYDPIDNLNLLHDSFPTSCI
YLSMLNFNEKFEELLPAL
>A0A8J7MXP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Odyssella sp|TrEMBL
MPTAPKSPGRLERALRAGHFAVTAETSPTATTDAAALVERCRPLAGLADAVNVTDGATAK
AHLSSLVLAGAMAASGIEPVLQFTVRDRNRIALQGDLLGAAALGVPNILALTGDDPKRGE
EPDAKPVNDINSTGLIALAKKLRDEGKLNSGRDIAGPPRLFLGAADAPMDPKPEWKPDSL
SAKIAAGADFVQTQYCFDLAMLRRYIARLAEHGIPEKVFILVGIGPLASAKQARWMHENL
WGVSIPEAIVKRLDAAADQKAEGRKICAELIQELATIPGVAGAHLMAPRQEAEMAAAIAL
SGVLKRRGAA
>A0A7G8UGH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. PAMC21692|TrEMBL
MFKEKILGKEAGILTYGMTPPKLTNTPQKIAEISQKQIERINDLDIDALILYDVQEEAER
VEEQRPFPYLPTIDPETYSDKYFNQLRVPQIIYRCVGKYSEEQFVNWVKADAERERYSVY
VGASSSRQAVNLDLSEASKLSKRLNSKLTFGGVIIPERHMKKNDEHIRVSNKIKNGCTFF
VSQATYNVEASKNFLSDYFYYCTNNGMEMAPILFNLAPCGSEKTLEFMKWLGISIPSWLE
NDLKYSNDILEKSIRLSQSIFEDILDFALEKGIPVGCSVESVSTRKLEIEASVQLVRDIK
CMLDKKLRRQQ
>A0A7X0V9V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides luti|TrEMBL
MGTGRGVGMAELIGRGERSFSFEFFPPKDEAGEERLWRAIAALEPYRPTFVSVTYGAGGS
TRDSTVRITSRIANETSLTPMAHLTCVGHTRAELEGILDTYAAAGVHHVMALRGDPETGP
RGEWTPTPGGLTHADELVELARSRGDFRIGVAAFPEGHPSAASLDHDADVLVAKARAGAE
FAVTQMFFRASDYFALVERVRARGVDIPILPGIMPILNLSAIRRQGELIGADVPEEVVAR
IAAHEGDKDAVRAEGIAIAAELCEELLAGGAPGLHFYTLNFSRATLEIFAALNVTV
>A0A1E9Q860|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC058E07|TrEMBL
MASIRRQVAVSQSLSLFTPGRVPFSVEFMPPRDDAAEERLWNAAEAFHDLGVSFASVTYG
AGGSTRERTLRVAKRLGTKPLTTLVHMTLVQHTKEELQAMLRTYASLGLTNLLALRGDPP
GDPNAEWVATPGGLNYASELIEMIRDMPECDDFDIGIASFPEGHYRTGSLEMDTEYTLAK
LRAGAQYSITQMFFDVDHYLRLRDRLAKADPEHGLKPIIPGLMPITSLRSVRRQMELAGA
ALPPQLERRLLDAAAGDEVANRDAIREVGIEVTTEMAERLIAEGVPDLHFMTMNNVRATQ
EVLHNLGMAPAWGPGLGHDMVR
>A0A3A5S399|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. AM28-20|TrEMBL
MTKQTPSLSFEVFPPNPEVGNAKLLRALENMQELAPHFISVTASNNKYNIKETTVALANH
IQNELSIPTIAHLPAIYLSKEKVADTLHDLDQVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFDVIGACYPEGHPDSPSQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVHHATKALFDHQPNLEVI
>A0A1H3GIS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aidingimonas halophila|TrEMBL
MLQVDHTEATPADHGIPSVTAPVEQRIQALAQDWSLEVTPGTAPSLLNSDEQAAVKRQVY
VTHLPGQPFADVIATAQRLKQSGHDPIPHLVARSIPDRETLRSGLERLTNEAGVSAVLLI
AGSMATPLGPYPDTLALLDDISLSRHGIHRLAIAGHPEGHFQADEDALDLALRSKLDYAE
REGLQAWVVTQFLFDAQPLIDWKAHLRQRGIDVPIRVGLPGPATLTTLWKYAMSCGIGPS
MWALQRQGGRLFKLAKARPPVEQVLGLAEQHDPALSLHFYPFGGIDKTLAWGQAIESGHF
QLDAQQQEIHVLT
>A0A158BTG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia ptereochthonis|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRATRAQLATLSPKFVSVTFGAGGSTQQGTLDTVLEMAA
EGFEAAPHLSCIGSSRENLRAILSQYREHGIRHIVALRGDLPSGMGAVGELRYASELVAF
IRQEHGDWFNIEVAAYPEFHPQSKSPRADLENFVRKVKAGANSAITQYFFNADAYFEFVE
EARKLGVDVPIVPGIMPITNFSQLMRFSDMCGAEVPKWIARRLESFGDDRESIRAFGVDV
VTGLCRRLIDEGAPGLHFYTLNGAWATKTICERLGFKSV
>A0A084B087|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stachybotrys chartarum (strain CBS 109288 / IBT 7711)|TrEMBL
MHIKDMLLEAQSNGQPSFSFEYFPPKTAQGVQNLYDRIDRMYSLGPKFIDITWGAGGRTA
ELTCEMVAQAQTVYGLETCMHLTCTDMDVAQVNDALKRAYEAGCTNILALRGDPPRDQDT
WTATEGGFLYARDLVKHIRETYGNHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDLGASF
IVTQMFYDADNFVRWVGRVRERGIDIPILPGIMPIATYASFIRRANHMQCKVPQSWLDVL
EPVKNDDVAVRELGKQLVAGLCKKLLAAGIIHLHFYTMNLAQATRMVLEELTWAPSAERP
FKQALPWKQSKGLKRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPQSISDISKIFLRYLDQKLDSLPWSESPLSSEADSIKDDLVA
LNARGFLTINSQPAVDGVKSSHPVHGWGPANGYVYQKAYLELLLHPDLLTEVLNRVSKHP
TLTYYVITKAGELRTNAPGDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAYRLGMDW
AHCYDTNSPSRAVISQIMNSWCLINIVNNDFHDSRLLFEIFNDLEVPNLNTPVTASNGNV
NGAINGNVNGSALKQSTIAGN
>A0A1I2B0R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces mirabilis|TrEMBL
MDGEHFRALLHSVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLATRLTAH
GCRVVPHVPARLLRDDAHLKDVVDRLREAGVDDVFVPAGDADPPAGAYDGALPVLRRLSE
LGSPFAHVGITGYPESHPLIHDDLTIQTMWDKRAYATYIVSNLCFDPRVLGDWVGRIRRR
DITLPVHVGVAGPVQRAKLLSMAAKIGVGESTRFLTKHASWFLRFATPGGYSPERLLARS
AGALSSPSAGVAGLHLFTFNQIAETERWRCAALDRLGG
>A0A259IBS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium 39-62-4|TrEMBL
MNASYDQLREARTALDTPLFAGLPGDINVSFEFFPPKTDALMVQLWDVVETLAPFAPHFV
SVTYGAGGSTRDRTHGTVARIIKDAKLPAAAHLTCVDATKAEIREVAESYWEAGVRHIVA
LRGDMGAPGVPFTPHPEGYANAAELVAGLKTIAPFEISVAAYPESHPDSPSQQADIDNLK
RKLDAGATRAISQQTADTRKTTVKTARAKRDAAKAALAQLQAQLAQTEVRAPAGGLVSAR
SVDVGQVVSLGTELVRIIRDNRLQVDARVPEGDLALVKEGGEVEVTGPDGTATPATIRQI
APVLDATTRLVVVHIDLPQGTALKSGMFARVGLKGAADRALAVPRSALVWRTGKAHVFLL
AEGRTAVLTPVETGRQADGHVEIRAGLSAGDVVVTRGAGLLSNGDHVQVVASATPASGEG
TPR
>A0A6A5RJ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Didymella exigua CBS 183.55|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTAMGFANLQSRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMDRALIDEALEQAKVLGIRNILALRGDAPRSEE
YRDEDKSPEQDSNKDFTWAIDLVRYIRKQYGDYFCVGVAAYPEGHSDESHPEHQNPSYDI
PYLVEKTQAGADFIMTQLFYDVGKFDRFETMLRQHESGAFKTIPIIPGLMPIQSYSILRR
TTKLSHANLPADLLARLDAVKADDELVKKVGVKILGEMVEHIKARRDAARRGFHFYTLNL
EKAVSHILEDTHLIGQIPTENDEDAIETTPAINLEPPSGVPLNKGRRRLSSLNSSPHNKV
IRERLSASKSNQSYETSDTEAGIPRGPVNTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSNASALKLWGRPETQDDISTLFKRHVEGTLEALPWSEQTLSE
ETKAIAPQLFALNAKGWWTVASQPAVNGIRSTDPVFGWGPKNGYVFQKPFVEFFIPSAAF
AELKPRLDAHEQITYFAGNAAGDFEASQEDAVNPVTWGTFAGKEIVTPTIIEAVSFKSWR
DEAFSIWKEWQRIYPTKSATGKLLRETRNDVWLVNIIWGDFVEGNGLWEFLGASG
>A0A7S0DBC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonas pusilla|TrEMBL
MDVGLVEALCDYSRPVFLFGLTPPLEGAKPEELRETARKFVERSATLATDGFIVYDIQEE
KGRTPEPRPFPFRKLDDPSHFAQVLKEVSGKESVVYKCVAEADPGGFDNWLETAIETYGV
NAYNLVGGASSANQYSGPTIPDVAAKLNARPQCAHGGVTIAERHIKKGNEHETLVKKSEL
GMQWFISQAIYDPEPMIKLLKEYGALCKQRKIAPKRVVLTFAPCGREKTMRFIKWLGVTV
PEDVEKEILEAENKVGKSVDLLCGMCKRILEETKGCGVPLGVSVESVSIFKNEIDAAHEL
FRRTQSMLLDFLGEPWLVRYSIVDKKSKRTSFDYQRPATPALPSTEEKPSSADDAAKQKG
ILVGAGLALGLVLGKVLRI
>A0A3M5CD38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas ficuserectae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLHNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A4V6P4I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia cinnamea|TrEMBL
MSGYPGRVTQLPDPDPTDGGRHPSIVERIATSTTPRVPFSVEFYPPRDEAAEERLWRAAS
VFSELGAAFVSVTYGAGGSTRDRTVRVVERIVRETDLVPIAHLTAVGHTVAELADMIRMY
GEVGVSNILALRGDPPGDPLGEWTAHPEGLRYAEELVRLIHEVGDFHVGVASFPEGHYRA
RDLDHDTEVLVGKLRAGAEYSITQMFWDVEHYLRLRDRAVAADPEQGDKPIIPGLMPVTS
LRQVKRMVELSGCALPDDLAERLRTAAGDGPEENREAVREVGIDLTTRMCERLIAEGVPC
LHFNTLNFSRATREVLTNLSMAPAPGVAASRI
>A0A3M5UPC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. avii|TrEMBL
MQSIQAFGEDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A0Q6X0A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelomonas sp. Root1237|TrEMBL
MSTLVSFEFFPPNTPVGVEKLKTVVQELGAMSPQYFSVTYGAGGSTRDKTLGAVMDIAAA
GFNAAPHLSCVGSTRENIAEILATYRAQDIHRVVALRGDLPSGTATAGEFRYASELVSFI
RETQGKDWHIEVAAYPEVHPQQRYAARDLQHFVDKMKAGADGSITQFFFNADAYFHFVDE
ARRLGVTQPIVPGIMPFHNYGRIAQFAQRDGIDIPRWVQMKMEGFMDDAASIRAFGLDVI
TRLCERLIDGGAPGIHFYTLNQSALTLELCKRLGLGNKV
>A0A6I5NVI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. SIOISBB|TrEMBL
MLPTDPTIPHAFPTSHFQKAAEAGDFLVTAEVMPPKGGDVSHMVEMAQQLRGRVHAVNIT
DGSRAVMRMSSMAAAAVLRQQGIEPICQMACRDRNRIALQADLLGAYALGIRNVLALTGD
PVKAGDQKAARPVFDLESVRLLQLIRQLNYGLDACDRPLPDQPVRLFAGAAIDPQCPSWS
GLQRRFTKKMEAGAQFFQSQLIDDFERLEKFMDQIAAGCNKPVLAGIFLLKSAKNAQFIN
RNVPGVTIPDHIIQRLADAKEPLREGMKIAAEQVKAAQDLCQGVHMMAIRREDLIPEILD
LAGIHHLQTVPSVTQREPAELSRLRFDRSKRLRNSEG
>A0A8J4H151|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylanibacillus composti|TrEMBL
MRKPDLREVLASGMLVGDGAMGTYLYQLGFPVGISYEELNLTRPEVIADVHRSYYEAGAR
LIETNTFTATRERLAKFGLEGETEAINRKAVQIARGAVGADAYVAGTVGSIRAGKRKNVS
QQTIKQDFEQQIGVLLNEGVDALILETFFDLEEILIALRIARSKSDLPIICQLAAEDVGR
TTDGYTLAHSFSRLAAEGADVIGFNCRSGPNGMLRNLERFRAEVEAQSAVDEVGEVGLSE
ASSLPVSVFPNAGIPDYVDGKYTYVSTPDYFAECARQFADLGARIIGGCCGTTPEHVKAM
ALALQNYIPQKKELALGSAAVPVQTEEPNDSKEAVASAAMPWSIQPDEAPSIVDTVMERH
TVIVELDPPRDLSIDKFMEGAEALKEAGVDAVTMADNSLAVTRMSNLALGYLLRDKLGIR
PLVHIACRDRNLIGTQSHMMGLDALGINHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRM
IKQLNEGVAFSGKPLKQKAQFVVGAAFNPNVKHLDKAVQRLERKIEAGADYIMTQPVYDA
ALIHDIHDATKHLRIPIFLGIAPLASGGNAEYLHNEVPGIRLPDHVRSRMAGLRGEEGRA
MGVQIAKELLDEALPYFNGIYLMTPFMSYHMTAELTRYVWEKTNRSNFHLSPLSK
>A0A845HM59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rugamonas sp. FT107W|TrEMBL
MANHNFSIEFFPPKTAEGAEKLRVTRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILA
AGEDAAPHLSCVGGTRESIREILAEFKAHNIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGEWFHIEVAAYPEVHPQAKSPQDDLLAFERKIKAGANAAITQYFYNADAYFQFVE
QTRKIGIDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQAAATTALWQRLV
>A0A6J4TMV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Solirubrobacteraceae bacterium|TrEMBL
ADRRGHRAQRPAGVLLRVLPAQDPGGRGEPRGGPRRARAARADLRLGHLRGGRDDRREAQ
DGRDRLAHQGAVRPRGDGPLHVRRGDGRRAALDARPHGRGRRRQRARAARRPAARRGGVD
GRRGRALLLARARGAHPRRVRLLHRRRGLPGDPRPRRVAGGRPPLPQGEGRSGRRLPRHP
ALLRQRGLLRLRRAGPRGRHRRADHPGHLAHHELQADRADLEAHRLEAARGAARRARGAG
RPARGGHRVRRRLRDAPVRRPAGQGRAGHPPLHAQPLARDPGDHVRAAGHGAVAWRRARV
>A0A2S6QXZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha9_Bin7|TrEMBL
MTDSAAYALKDSQSTHPKSRLERLLRSGTFVATAETTPPISADPTPLLDVTYELRNRADA
VNVTDGAGAKSHMASLAAASILVGAGIEPVLQFTVRDRNRIALQGDLLGAAALGVSNILC
LTGDNITAGDQPDAKMVMDLDSRGLMTLARDMRDKAQLPSGRPIEKTPSLFIGAADAPQE
PNNGWNAAALHAKVDAGAAFFQTQFCFDADLVRRYMNRLEGEGVLERAYFLIGTGPIASA
KSALWMNQNLFGVDVPEHIITRLEKAKNQSDEGCKICIELVQQLRSIPGVSGVHLMGPRV
ENAAAQVIADSGILNDRPEVI
>A0A2G8CSX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter sp. OAMSW11|TrEMBL
MNATLLTGSAPTRARFSFEVFPARSGAAALALGHAVQHLSAAGPDFISVTYGANGSNRDA
SLDLLRYLRDHTDALPLAHLTTVGETREAVRATIHGIMDAGVHDFLALRGDPPRGSTEDD
PLVSGSLSALELTELIAEARAERPALTSVGRTAVAAYPNGHPMSRSRSEDLDWLVAKQEA
GAQFAITQLFFEAEEYLSFVSDARDAGLRIPVLPGLMPVSTSAQLRKVASLAGRPAPAAL
ERALEEAGGYAPELGVEHTISLAGELLAGGAPSVHLYTFNRHEQVLAVLRELNLLAPVG
>A0A0F6L767|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei MSHR4000|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A5C2TGQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentinus tigrinus ALCF2SS1-7|TrEMBL
MKISQKIEQAAKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
ELTSELVKTCQKLIGIETCMHLTCTGMPKEKVDIALREAKQHGCRNVLALRGDPPVGKEW
EAVEGGFHYGIDLVRYIRKQYDDYFDIAVAGYPQTHLLPPEEAALEMQYLKDKVDAGANF
IFTQMFYDIDMFVDWVRAVRAAGITIPIVPGIMPIQTWNGFQKATSLAKITVPQAFLDEL
EPHKNNDEKVRELGTKLVANMCRQVLAADLGIKGLHFYTMNLEKGCRMLLEELNLVPRVE
VVKPLPWRQSLTPNRRAETIRPIFWANRTRSYLSRTENWDEYPNGRFGDSRSPAYGELDG
YGIWLKQSKDDALKLWNTPTTVDEITALFAKFCLGQLQALPWSDSAPSSETTVIAQQLAK
LNSLGFLTINSQPAVDGARSDDRIHGWGPANGYVYQKAYLEFFVSPELLDMLIPHIERDI
NITYYVINNRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGRQW
AKLYDPDSPTRKLIDGIMDSYYLVNVVHNDFKKPEAIFEPFFKAGAEYAAKHDAPKTNGH
AH
>A0A2E7LGD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MSLASIYQQQKTVISCELFPPKTPQGDAALFRHVAKLMEQNPAFVTCTYGAGGSTRDKTL
DVVQAVKRDFSVPVASHLTCVGASVDQLRQFLQEALERGVDHIVALRGDPPDGVDAFRPV
EGGLRYANELVALIRNEFPQFGVAVAGYPETHREAASSEADLQNLVRKVRTGADVVLTQL
FYDNQSFFTFRDRCRALGIEVPIVPGILPITNLSQIKRITALCGAVLPDALLQQLAARDD
ADSQYRVGVDFATQQVAELVKGGVPGIHFYVLNKSLATCEVLEAVDL
>A0A4V1B1E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S501|TrEMBL
MALGTPSTRTDHARTVRELLATGETSFSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVRYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDSDIGHFVD
KCRAGADYAITQMFFQPESYLQMRDRVVAAGCETPVIPEVMPLTSVKQLERFAQLSNASL
PSALKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A2U1SP98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylosinus sporium|TrEMBL
MSDNRSLWPPGHFDISYEFFPPKTPEMEAQLWDSIARLAPLKPKFVSVTYGAGGSTRERT
HNIVARLAAETDILPAAHLTCVSAAREEIDEIVRDYRNAGVRHIVALRGDPPTGVGTKFE
PHPRGYRSSTELVRGIRAIGDFEISVSTYPEGHPESRTIDDDLDALEAKIDAGATRAITQ
FFFENDVYFRFLDKARARGIKIPIVPGIMPVQNFKQTANFARKAGASVPDWLAHRFEGLD
DDPVTRRLIAAAVAAEQVLGLAENGVREFHFYTNNRADLVFAICHLLGVRPVTEKAAA
>A0A2V2QP80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. FT05W|TrEMBL
MALGTPSTRTDHARTVRELLATGETSFSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVRYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDSDIGHFVD
KCRAGADYAITQMFFQPESYLQMRDRVVAAGCETPVIPEVMPLTSVKQLERFAQLSNASL
PSALKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A0W0HSN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens ICMP 11288|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITQMCEQLLQGGAPGLHFYTLNQTEPSLAIWNNLKLPR
>A0A5C2TTE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentinus tigrinus ALCF2SS1-7|TrEMBL
MKFVDKIAQHDARSLFYTFEFFPPKTDQGFENLVARIARMVTLNPLAVSVTWGAGGTTKE
RSLDLAGLTQLEYGMDTILHLTCTNMVQGTVDAALREAKERGIENILALRGDPPRGAEHW
IPTDSRFQHGADLVRYIKSTPEFADFCVGVAAYPDGHPDRETNEDGEIEHLKEKVDAGAD
FIITQLFYDVDGFLQWHQKVRAKGITVPIIPGIMPIQTYASFLRMTKLCATRVPPKMMHD
LVPIRHDDQKVKEYGVKLAVDMIKQLQAGGIQGVHFCTLNLEKSVTRVLETLGLAGNISQ
ATNKLIADVATPPERTMTPHAASDRATKELASVPAPESDAGKGEINNAADWDDFPNGRFG
DFKSPAYGETDRWGSSAFQSKALAVPLSQWGNPKTADDLTSLFLRYLHSKVTATPFSSTP
LSPESLMIFPHLERLTSKGWWTVGSQPPVNGAPSTHDIVGWGPRGGYVYQKCFVEFFVEQ
KDVERIVKKVEEEGAGWISYFAGNAKGELLTNVPEGGRNAVTWGVFPGQEIAQTTIIEKE
SFLSWKDEAFSIWSEWASFYPPASQERSLLEGIYNGRWLVSLVHHDYLDPATLWTFLFKG
DHPLL
>A0A095Z7U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium freneyi DNF00450|TrEMBL
MSEFPPPAVGRQVPIRHALTLPSPGPIPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFA
SVTYGAGGSSRDRTLRIAERVSREPLTTLVHLTLVGHSVPELRQILRAYLERGLTNLLVL
RGDPPGDPLGDWTPTSDGLRYASELIELIRDEEEFADFEIGIASFPEGHFRAPDLESDTR
YTLAKLRAGAEYSITQMFFDVDHYLRLRDRLVAADPEHGAKPIIPGLMPITSMRSVRRQL
ELSGSALPPALDERLTRAAAGDEEANRDEIRKVGIEVTTEMAERLISEGVPGIHFMTLNF
ARASQEVLHNLGMAPAWGTGQDMVRGGF
>A0A0F3KFW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter yeojuensis|TrEMBL
MKNAHANDLTAGYSLEVGTKSMAALTEAAPWIPRGTVIAIPYLPGEDDTARLSAARDVRR
LGFEPMLHIAARHLHSRAELEAFIEHAAREAGVERFFVIAGDVAQPKGPFADSLSLIDTG
LFERWGAKVVGVGGHPETHSIMSMDDRWDVLQRKCAHIAERGMTPLIITQFAFDASAVVA
WLEALRGRGLQYEVRIGVPGPAGIATLARYAALCGVGASVSMLAKHGTAMGKLLGVKGPD
HFVDQLGEGIRDAHEAVTLHFFPFGGVGKTVTWIDHYARRAEQAGSSLTACRTPP
>A0A0Q7JW23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Angustibacter sp. Root456|TrEMBL
MALGLPSTLPSGAATVHESLRDLLAAGGRSFSFEFFPPKDDAGEALLWTALRRLERLRPT
FVSVTYGAGGSTRDRTVRITERIARDTTLTPVAHLTCVSASVGDLRRVIGQYADAGVRNV
MALRGDPPGGPGAPWQSHPEGLDHADQLVRLLREMGSFCVGVAAFPDKHPESPDLDHDAD
VLVRKGEAGADFAVTQLFLDPHAYVGLVERVRARGSDLPIIPGIMPITSLAQVRRFGELS
GVAVPDVVEQRLRRAGDDPAAVRAEGMAIAVELCRDLLDAGAPGLHFYTLNRSTATLEIY
ETLGLSAWPAAS
>A0A0S9C540|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Leaf69|TrEMBL
MSPPSLIDTHPNLAGTAPVALSYELFPPRSPAAAESLWTTIGELESTDPDYVSVTYGASG
SNRDTAVELINRLVQETTLRPLAHLTCVGNSPQELAEIIGELLDVGVRGILALRGDQPKD
GGVPPEGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLLTRARRAGVTIPIIPGVMPLTSIRRLTRLGELTGVE
PAPELIDRLAAADTDAERTRIGVGATVDLANAALDAGAPGLHLYTFNEHSAALDVLDKLA
LARPQRGNRHGGNRHSSHRPTAGRRQLAS
>A0A374L607|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. OM04-4AA|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPD
AMKQAGIVYATDQIIDLLANGVNNIHIYSMNKPEIAVAIMNNLSEIIKC
>A0A5Q4GF73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
YGAGGSTRDKTLEIVSQVKRTFDVPVASHLTCVGSTVPQLRDYLGRAAEAGIDHIVALRG
DPPKGTTEFTPIEGGLRYASELVGLIREDYPQFGVVVAGYPEKHQEAPSMDVDLENLKRK
VDAGADVVVTQLFYENFDFFRFRDRCERMGIRVPIIPGIMPITNLSQIRRISSMCGARLP
EAFVWRLQENEDPDWQFQVGIDFAIVQVEQLVREGIAGVHFYVLNKSQAASHVMQAVRLP
R
>A0A0D2T8L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium raimondii|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFDRMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFIKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQFPHGRWGDSRNPS
YGALTDHQFMRRRARDKKLQEEWATPLKSIDDIQEKFKSFCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGELSDSLSVGKYKC
>A0A355G437|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MRISELYQDGTFGLSVEIFPPRNESGDAELFKTLEELVRYQPAFVSCTYGAGGSTSKRTI
ELCALIQDQLHNTATAHFTCVNSTREELVEWLHNAVDAGITNIMALRGDPPAGQETFVPA
DGGLKYANELVSLIRQHFPDMGIGVAGYPECHPEASDSAFDLTNLKRKVDAGADAIYTQL
FFNNEHFYQFRERCQQAGINRPIIPGIMPITEYRRIQRIMSMCSSEFPADLVGQLEAVQD
DLDAQFEIGVNYAIRQCEQLMEVGVPGIHFYVLNRSQACKRIFDALGFPETQDKIAT
>A0A8J7UIZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tianweitania sediminis|TrEMBL
MSRLPASIEVAPKQAIESADLPGLLPAGTRVYITDIGTDPADVLTAAARRVHDLGYKPVP
HFASRRLTTRAALEDRVKRATSEAGVTDVLVIGGGLDAPAGEFTSTMDVLNTGVFERHGI
TAMGVAGHPEGSPDFSEHTAIEALREKQAFARRSGIDVRIVTQFGFDADRFADWAEGLKN
NGIDLPVHIGVAGPAKIPTLIKYAAMCGVGNSIQFLKKNAMSLTALAVGHSPEEIVSPLE
RRAARPQSPISHIHVFPFGGLKKSAEWLAERGSLDIKTSAYASA
>A0A6L7XMG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MTRPSISFEFFPPADAGAVQRLQRVMNLLVRLGPDFFSVTYGADGSTRSRTERLVCWIRQ
ELPVPPAAHLTCVGSTRSQTDALARRWWSLGIRHIVALRGDPPKGTDRYCPEPGGYRHAA
DLVRGIRAAADFEISVAGYPEPHPESPSPAADIENLKAKVDAGADRVLTQYFFDNACFLR
FRDRCSTAGITAPIVPGILPVTDFARVAEFSRRCGVTIPPHMVAIFEPLDTDARTREMIA
AGAAVSQCEDLRREGVNAFHFYTLNRARLSYAICWWLGLRGRIEAPSAGAADPNA
>A0A8J7R2I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tianweitania sediminis|TrEMBL
MTVHRLSRRPDLGTRLRVSFEFFPPKTDEMERRLWDTVLRLEPLNPHFVSVTYGAGGSTR
DRTLRTVSRIARETSLPPAAHLTCVGASREETDAVIASFAAAGVTRFVALRGDPAQGVGA
AYAPHPEGYTNGADLTAALSRQGNFDVSVSAYPEKHPESADFATDIDMLKRKVDNGAVRA
LTQFFFENDAYERYVERVRRAGIYVPIVPGILPIHNFSQVANFAGRTGATIPGWLARRFD
GLEHDPQTHALVSAAVAAEQVQDLIERGIEEFHFYTMNRADLVFAICHMIGIRPLEHEGK
TRTPAAA
>A0A420HP52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysiphe neolycopersici|TrEMBL
MEKITDKIAALPHGSNYFSLEFFPPKTSTGVSNLRTRLDRMSRALRPLFVTVTWGAGGST
ATNSLELAELCQRELGLTTCLHLTCTNSSQRVVDETLEKAYALGIRNILALRGDPPRKEY
ISTELGTEETVKFEWAIDLVKYVKEKYGDYFCVGVAAYPEGHVDRDDPDSQSLEHDLPYL
VEKVKAGADFIMTQLFFDIDAYDIFQKRLREHESGCFKMMPIIPGLMPIQSYQMIQRTIK
LTHVKMPPQIAARLDATKGNDELTKEVGVDIVSEIISHIQHDPLPLLGRRGFHLYTLNLE
KVVSLILERTCCD
>A0A0H3JSU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus (strain N315)|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A2V7BH67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFSQRLAAGALLCDGAMGTMLYARGVSLDACFDVLNLNNPRLVQAIHADYVAAGADL
IETNTFGANRFKLAVHGLEGQVREVNRRGVRLARDVRESTGRDVLILGSVGPLGKYLAPL
GSVTAEDARAAFREQAEGLLEGGVDAFIVETFSDLAEIALAIEAIRSVTDLPIAAEMAFT
DEGVTFTGRSPAEVARTLRALGVQALGANCSVGSSTLYGVLEQMVEVAGGLPLAIQPNAG
LPSRVGERLIYLSSPAYMAEYAARMVDAGARVVGGCCGTTPQHIAAMRETLDRKRPPRRD
AVRPTVTVTTPAVGESAGLLTRRPATPLQRKLEAREFVVTVELDPPRGHTVERLVQGAKL
LKERGVEIVDVNDGSLGRVRMAVLPTALLVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALDVRNILALKGDPPRAGDYVNTTAVFDVNAIGLIEVLKRMNQGLDATGNSIGTPTSFCV
GAALNPGAENIKAEISRFQRKVHAGAQWLQTQPVYDLAELDRFLEQAGGPPVPVIVGVLP
LHSYRHAEFLHNEVPGITIPEHIRARLRDAGDGALRVGIEMAQRLLHEIRGRYAGAYLVP
SFGRFEVVAEVLDALH
>A0A6M2CCC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. XN-5|TrEMBL
MKVTEHIEAAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMDFNPPFIDVTTSREEFIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYTVDTVPHVLCGGFTKEETEYLLVDCHYLGINN
VMALRGDAMKDEQSFVPKSGGNNFAVDLVQQIDLLNQGKYLHDVMHIDNKADFCIGVAGY
PEKHLESPSLLSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVDKARAMGITVPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIHAVDQCKTNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A1Q9SC81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria sp. CNJ-770|TrEMBL
MPTSTPTGSPAAVQMLPGFSLEMTGRDVPALQEAGPGIPPGTRINVTFLAHEDPALRVAA
ARAVREHGFVPVPHVSARRLRSRAELDAFLVHLAEAGAAEQVLVVGGDPGTAQGPYEDAL
AVIRSGALQRHGVRGVGIGGYPEGHPAVDDDVLWSALAAKTAALREQGLEATVITQFGFD
TAPVLSWLAEARRRGIDAPVRIGVPGPAGVRRLLGHARRFGVATSAGIAQKYGLSLTHLL
GTAGPDRFLHDLAAGYDAEAHGPVRLHFYTFGGLGATACWVRQFGGERVAP
>K3WKM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Globisporangium ultimum (strain ATCC 200006 / CBS 805.95 / DAOM BR144)|TrEMBL
MKIIDKINQCIEKNEVFYSFEFFPPKTPAGVDNLYTRMDRMASLEPLFCDMTWGAGGSSA
QLTIDISANAQKLSGLEMLMHMTCTNMAEEDVKNALEKAKDAGITNILALRGDPVRGAVS
FNECDRGFSHAVDLVRYIKEHYGDHFSIGVAGYPERHAESVDSATDIKYLKEKIDAGADF
VITQLFYDVNVYVKFVEDCRKVGITCPIIPGIMPIQNYGGFVRMTSFCSTYVPEEITTAL
EPIKDNDEAVKDYGVELGIEMCKQLMAAGAPGLHFYTLNLERSVRRILDGLSITSSNASR
RELPWRPSTLSKRSSETVRPIYWSNRPKSYIQRTALWDEYPNGRWGNSESPAFGDLSESH
YFSTNVTPQNRKAMWGEAPVSKDDIHQTFVKYVRGEISSLPWCDSPLHLETKTIQDKLAA
INAAGFLTVNSQPRVNGARSDDPLFGWGGPGGRVYQKAYVECFVSPENMKKIIEAASTKR
YIQYHAVDFRGHSYSNAGKSAIAVTWGVFPNKEILQPTIVDSSSFMAWKDEAFALWLSLW
ASLYDDESAASEVIHEIHDTFFLVSIVDNDFINGDIWSIFDAQPSPNAAP
>A0A2S6U925|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha3_Bin2|TrEMBL
MNRNAPLAIASPLPNDVRVSFEFFPPNTEKANETLWNSIQRLSPLKPSYVSVTYGAGGST
RERTHATVYRLRHETDLEPAAHLTCVGATTDEIDDIARSYWDAGVKHIVALRGDPAEGGG
PYQPHPGGYAYASDLVAGLKNIADFNISVAAYPETHPEATGAEADLDNLKRKIDAGASEA
ITQFFFDTDVYLKFLERARAAGITVPIIPGILPVTNFTRVAEFSDKCGTKVPHWMADLFD
GLDDDPQTRKLVAAGVAAEQCRALHTEGITDFHFYTMNRADLVYAICHILGVREKREA
>A0A2D9I622|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MSHAIRIGFEVFPPKSGSSETFENSVATLATIGDYVSVTYGASGSGRERSETAINALVAK
GQANKIAAHLTASSQSRDQIDRLARDWKAKGIHRIVALRGDAPAVTGDEYPCAAALTEGL
SKIGGFDIAVACYPEGHPKSASKAAEMDHLKRKFDAGASEAITQFFFNIEDYLRFRDDCR
AAGIHQPIIPGLLPIASLEGLHRFAAGCGAKVPGWLDARFAGLEDDPETVRTLSVATTVS
LSDRLIAEGVDHIHLYTLNRVRDALTIARALGITGTESAVITQKEEAA
>A0A0B2AJH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinomonas humi|TrEMBL
MSPPTLIEAPSSSALAPPVALSYELFPPRSDAASATLWKTIHELERTDPDYVSVTYGASG
SNHAKALDLVDRLQIETTLRPLAHLTCVGGTPAELSAIVNELLDRGVRGILALRGDRPQD
GVLPRDGLQYAQDLIELIRRIELRRSAQFAAGKIAIGVAAYPTKHPESPSEAHDVEVLLA
KQRSGADFAITQVFFHPGQYSSLVHRARRAGVTIPIIPGIMPLTSLRRILKLSELSGVEP
DGALVDRIRSVGDDASLARKIGVEATVALAEAALDAGAPGLHLYTFNEHESALDVLARLN
LPRPSRPSLLARHRAR
>A0A1V9DM82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea latae|TrEMBL
MSFFHANQREALNQSLAELNGRINVSFEFFPPRTSEMEETLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRAIAQDYWNSGIRHIVALRGD
LPANSGKPEMFACDLVSLLKEVGDFDVSVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLTRFATMTNVRVPGWMNAMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVIAA
>A0A6A7MN18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriales bacterium|TrEMBL
MSGSRTPTTRLRNALADALRSPRYEVLPLPGVDELVAEFVPRRLTVTVTASPRRGLDATL
DLTEQLSAAGFEAVPHLAARQVVDASHLAEILARLDRAGVREAFVVAGDLAEPVGPHRDA
FALLSMMHRLGHGLDRVGIAGYPAGHPYLSDAQLRRAMSDKAAFATYLVSQLCFDPALVS
AWVEDVRGNGVRLPVHVGIAGVVDRRRLLRIATRIGVGESARFLRKHRAPMSHLVLPGGY
RPDRLLRGLAPDLATPERRVVGLHVYTFNDLRATESWRRQALARLEDAA
>A0A268RZF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus clausii|TrEMBL
MELRDKLKTSLIVGDGAMGTLLYEQGFDLCYEELNLSQPDAVYNVHRSYIEAGAKLLQTN
TYAANAVKLKKYGLDESVADINNAAVRIAKKAIGNDEQLALVGTIGGIRGFLHEETENKA
ITAALLEQITALLEAGVDGLLFETFYDFEEAKEAVALARRLTDKAIIMNVSMGDIGVLNG
GIPLGEALERLHQLGADVLGINCRMGPYHMLRSLEQLELSSAFPLACYPNASLPGYRDGR
FVYASNTDYFYEMTGAFIEQGVHLIGGCCGTTPGHIAAIAKAVETNTPKTRSLIVRRPSQ
LQEEAPGRGERLNEPLDQLARRKQTIIVELDPPKKLTIAKFMEGAKALKEAGVDALTLAD
NSLANPRIDNQTLAMLVREQLGLRSLVHLTCRDRNLIGMQSHLMGLHLAELHDLLVITGD
PSKIGDFPGATSVYDVSSLKLLPLIKQMNEGISFSGNSLGSKASFSTAAAFNPHVKHLDK
AVRRLEKKIEAGADYFLTQPIFDEQQFEQLYNATKHLPVPIFVGIMPLTSSRNAEFLHNE
VPGMTLSDETRARMAACGNDKEKAEQEGLQIAMELADAASTYFNGLYLVTPFLRYELTAA
LATHCRAIANPTNHTMEGERI
>A0A839EXQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dokdonella fugitiva|TrEMBL
MASVPISFEFFPPKTDEQRATLEAALPKLKAIAPEYVSCTFGAGGSTLSYTPETIRHLRE
EHALDAAPHLSCMGGTRAEIRTLLDRYAEMGCRRIVALRGDLPSGMASYGDFRYASDLVE
FIRKERDGRFHIEVACYPEVHPQSDDAHADLRHFKAKVDAGANGAITQYFYNPDAYFRFI
DAARRGGIAIPIVPGIMPIANFTQLKRFSDLCGAEIPRWLSKRLHAYGDDVDSIREFAAD
VVAELCDRLVAGGAPGLHFYTLNRARATLAVIERMHRR
>A0A0A2VT16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beauveria bassiana D1-5|TrEMBL
MEQTLWKSIDRLSILKPTFVSVTYGANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATR
DELRAIAQDYWNNGIRHIVALRGDLPPGSGKPDMYASDLVGLLKDVGDFDISVAAYPEVH
PEAKSAQADLLSLRRKIEAGANRAITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSN
FKQAKKFADMTNVRIPSWMAQMFEGLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYT
LNRAEMSYAICHTLGVRPTL
>A0A803M5F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chenopodium quinoa|TrEMBL
MKVIDKIKASESSNQTLFSFEFFPPKTEDGVENLFERMERMVSHSPSFCDITWGAGGSTA
DLTLEIANRMQNIVCVETMMHLTCTNMPVEKIDHALDTIKSNGLQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHMRKKYGDYFGITVAGYPEAHPDAISENGLATPEAYASDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYRGFIRMTGFCKTK
IPQEITDALEPIKDNDEAVKAYGIHLGTEMCKKILASGIKQLHLYTLNMDKSALGILLNL
GLIEESKIQRPLPWKRPANVNRTKEDVRPIFWANRPKSYITRTKGWDQYPQGRWGDARNA
SYGALSDHQFMRPRSRDKKLQEEWAVPLQSVEDINEIFKNFCLGKLKSNPWSEIDGLQPE
TKIIDEQLSNINKKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYVEFFCSREKLN
ALVEKCKGLTHITYMSVNKGGDWISNVGQTDVNAVTWGAFPAKEIIQPTVVDPASFMIWK
DEAFEIWSRSWAQLYPEGDSSKKLLEEVQNSYYLVSLVDNDYVTGDLFSVFATL
>A3N0L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus pleuropneumoniae serotype 5b (strain L20)|TrEMBL
MSYAKEIDHLNHTLADLNGNINASFEFFPAKNEKMEMLLWDSIHRLAPLKPKFVSVTYGA
NSGERKRTHSIVKRIQQDTGLAAAPHLTGIDANPEQLRIIAQDYWENGIRHIVALRGDEP
AGYAKKSFFAKDLVKLLKEVADFDISVAAYPEVHPEAKSAQSDLIYLKQKVEAGANRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVTNFKQLQKMTKITNVKVPHWMHKMYEGL
DDDQTTRNLVAASIAMDMVKILSKEGVKDFHFYTLNHSELTYAICHALGVRPT
>A0A1Q7N6A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_40CM_3_56_11|TrEMBL
MQDLLTRLENHVLVCDGAMGTMLYSKGVFISRCFDELNISNPELVREVHLDYIKAGADII
ETNTFGANRTKLMTHGLADQIRHINIQGARIAGDIAGDNILVAGAIGPLGIRIEPWGKTA
IEEAQVTFREQAKALVDGGVHALILETFFDLNEVYAAIRGVRDVTDQPLIVQMSIEEDGN
SLEGTPPEVFAKRLEEWGADVLGLNCSVGPQIMLDAIERIANVTSKKLSVQPNAGKPRNV
EGRNIYLGSPEYMASYAKKFVQYGVRIVGGCCGTTPQHIKAIRAAVKSVGVAVLGPSPGA
SRRPLPAGEGTEGESSIPLESRSRLGRKLATKEFIKIVEMIPPIGHDFAKAIEKAKYLQA
QDVDAINVPDAPPSSARMSAISLAVLLEKSTEIESLAHYTCRDKNLLGMQSDLLGAYALG
LRNLLLITGDPHQIGEHSDATAIYEVDSIGLTNMVSRLNGGVDVGGKSIGKPTGFVIGVG
ANPGAMSDLELKRFFYKVEAGAEFVLTQPVFDATVLERFLDRAGNSKIPVIAAIVPLPNY
KTAEFLNYEIPGCSIPDSILERMREAQSKSPEHARNEGILIAQEILERIHGTVQGVQIRG
PFDRYETPVEVLSVPMKGATR
>A0A6A7MLJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriales bacterium|TrEMBL
MRNKDKAVVLRGLLERARYEVLPTASIEDTVCAEVPPGRTLTVTASPSKGLEATLSLAER
LVGHGYDVVPHLAARMISGSSELKEIVERLVPLGVTTVFVPAGDADPPAGSYEGSVELLE
DLTTLGRPFPNVGITGYPESHPSIGDDLTIQAMWDKRHFATQVVSNLTFDAALLRTWVTR
MRARGITMPLLVGLPGPVERTKLLAMATKIGVGESTRFLAKHKSTFARIAAPGGYSPEKF
LEKASPVLGDPLSFVAGLHVFTFNQVAETERWRAGLVARLGGPVGAAS
>A0A059KX46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mandelii PD30|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A345Q9V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. SK011|TrEMBL
MIDLDGVGTDHFAYIKPPEGHVSHSRLERVLRSGRFAVTAELNPPDSADPADVFEAAQPL
GEVADAINATDASGANCHMSSIGICALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAALG
VSNVLCLTGDGVGVGDQPGAKPVFDFDSLTLLRTIRTMRDKGVFLSGRKITRPPQLFLGA
AENPCIPPYDWRPDRLIKKIDAGAEFIQTNYIFDIPLFERFMARVRDEGAEKRVFIIAGV
GPLASAKAARWMRSNVPGIHIPDQIIARMEGAANPSEEGKKICIELMQQLREIEGVAGVH
IMAYRREHLVSSIILESGVLAGRRSAKRR
>A0A520DAH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRRQLYATRPEFCSVTYGAGGSTHAGTFAAVREIIEE
GVPAASHFSCIGATRATVRAQLAELRAMGVRRLVALRGDLPSGYGIGGEFQYASDLVEFI
RAETGRDFHIEVACYPEIHPQARSPEADLQAFATKARAGADSAITQYFFGAEAYFRFVDD
ARRLGVDIPIVPGVMPITSSTQLMRFSDACGAEIPRWIRLRLNGFGDDVESIKSFGLDVV
ADLCERLRDGGAPSLHFYTMNQAAAPLAVLDRLGWSA
>Q5AU15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)|TrEMBL
MEKITHKIAALPPGANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCVGVAAYPEGHPADSFQDIQDPKVDLPWL
VEKTQAGADFIMTQLTYDIDAYTEFENLLRNHESGTFKTIPIIPGLMPIHSYKILTRVTK
LSHVKIPPPILAKLDEVKHDDDAVKRLGVDILAELVDGMKKLPTPGLRGFHFYTLNLEKT
VSFILERCKLIPDHDDDAEAVADGVSLLTVDAEIANRRRRASSISSLPHNRVIVDKVSNG
SSKDSVTHEATAASAGLPAGPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFG
EIDGYGPSLHVAPSVAHRIWGYPVSTDDISKLFRRHVSGDLHMVPWSEGGAEENTSGLNA
ETETIRPELLALIDKKGWWTLASQPAVNGVRSDDPIFGWGPPGEGFVFQKPFVEFFCPAS
DFKTTLKPLLQKHGHEKLAWFATNAAGDFESSLPAETSDTEPVEMNPNNVNAVTWGVFRG
KEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKSSATEKFLEKTKNDVWLVCVVGQDFG
AGTEVGSKEEDDEKKWMWRLLADC
>A0A031IBQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia sp. RIT313|TrEMBL
MSFPISFEFFPTKTPEGAAKHVQVRKNLYARKPQFCSVTYGAGGSTQAGTFNMVRDIQSE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPHSDLEAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A4Q1V978|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. Tri-44|TrEMBL
MMNAFRPSRHGSRRPRVSFEFFPPKNEEMAVSLWESVRRLEPLGPAFVSVTYGAGGSTRE
RTHNTVKRMVDETGLKPAAHLTCVSATTDEVDEVIRAYWAAGVRHIVALRGDPAGGLGST
YEPHPQGYHQTSDLVAGIRKVGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAI
TQFFFDNDVYFRYLDKVRAKGIEIPILPGIVPVQNFKQTANFARKTGASVPQWLADRFEG
LEDDAATRRLVAAAVCAEQVLDLIDRGVSDLHFYTMNKADLVYAICHLVGLKPEKAQAQQ
VAAE
>A0A521NY36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAARQQLYARKPEFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRETVRAQLAELKAMGVKRLVALRGDLPSGYGAGGEFQYASDLVAFI
RAETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVKAGADSAITQYFFSADAYFRFVDE
ARALGIGTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIKAFGLDVV
TDLCARLREGGVPALHFYTMNQSAATLAVLERLD
>R0CW24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] clostridioforme 90A6|TrEMBL
MDDAEGRERLKMKIREILAEGKPTLSFEVFPPKTEDAYDSVEKAAAKIAKLKPSFMSVTY
GAGGGTSDYTVGIASAIKEEYAVTPLAHLTCVSSTREKVHHVLGELKERGIENVLALRGD
IPQDGSTPKEYHYASELIREIKKAGDFCIGAACYPEGHVESANKSVDMDYLKQKVEAGCD
FVTTQMFFDNSILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTCLPSRFMSI
VDRFGDNPAAMKQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A0A2W5W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beauveria bassiana D1-5|TrEMBL
MHIKDLLAETKRSGKPSFSFEYFPPKTAQGVQNLYDRVDRMYNFGPQFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGMEKVNDALRKAYKAGCTNILALRGDPPRAQEK
WTATEDGFQYACDLVRHIRATYGDHFDIGVAGYPEGCDDNDNEDELIEHLKYKVDLGGTF
IVTQMFYDVENFIRWVGKVRAAGITVPILPGIMPIATYASFLRRCKHTGCKIPQSWLDLL
EPVKNDDVAVREVGKKLVVDMCRKLMAADIHHMHFYTMNLAQATRMVLEELNWTPSAERP
LQQALPWKPSKGFGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRLKWGEPKSLRDIANTFVRYLNQEIDSLPWSEAPLTSEADSIKPALIE
LNQRGFLTINSQPAVDGVKSSHPVHGWGPANGYVYQKGYIELLVSPKIVDQVIQLVNTNP
SLTYYAVTKNGNLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFDAKSPSRVLVESVMDNWYLLNIVNNDFHDNTTIFELFRDLKVDGLDTPIAVEAEAT
VAAEAEKPAAAQAEAVA
>A0A2G4SU89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus microsporus ATCC 52813|TrEMBL
MKITTKIKKAEDEGRMFYSFEYFPPKTAMGVQNLYDRIERMQRFGPEFIDITWGAGGSSA
DLTTEIVATTQSVYGLETMMHLTCTNMPIEKIDKALEAAKQCGCQNILALRGDPPKGQLN
WESCENGFNYAIDLVRYIRDKYGDYFCIAVAGNISTHITTGHPEGHIDNPDKDDDLLRLK
QKVDAGADLIVTQLFFDVDIFVDFVKRCRDIGIQCPIIPGLFPIQSYSSLSRVISFNKNH
VPQKIWDDLETVKDDDQAVKDYGIDLTIQFIKRIKQETSISGFHIYTFNLERSSRLILEK
LGLVPEQEYVKPLPWNPSLTPTRGKENVRPIFWKHRTQSYIQRTESWDEFPNGRWGDARS
PAFGEFDRWGVSIKYPPEKQLAMWGTPESVDDIALLFAKYCKGKLEALPWSAQKLDPETD
IIKQRLAAINFLGYLTINSQPAVNGARSSDPVYGWGPRNGYVYQKAYIEFFVSPEQLQVL
IDKMSNEPEITYFAVNYKGELKTNTVYKEPNAVTWGVFPGKEIIQPTIVEETAFMAWKDE
AFELWSEWARIYDRKSPSAEIILDIHDHWYLVNIVHNDFQDEDGIWRLFDLEIDGDLSRR
LRRGSGSL
>A0A5R1QJ82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. BCA17|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAAQLATYHPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A5N7EGI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus pseudocaelatus|TrEMBL
MHIKEKLAQNEAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAADGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGATF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYSAFIRRANWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDQLKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIRDLSHLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLVE
LNNRGILTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIESNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDNWYLVNIVNNDFHNTYDLFDLFKDLNVRDFDVEVTADNADSK
SQENEAAGATAN
>A0A514LGY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salicibibacter halophilus|TrEMBL
MEVGFGDIVQPMCPRSNLYLPISILQMKEGMAIMEMMDRQSSAERIGRMNEPRFELIPAN
RIVERATAALPPHATLTVTCSPKKGVDATIDTAIALAPRFAGVVPHIGARMVRSEKHLEG
ILDKLRINGLEEIFVIGSDQKQPLGPYRYGFELLRSLATRDHGLRRIGIPAYPEGHPNIN
NDILAEDLLVKAPFVHYAVSQMCFDSDQVLAWLRQQREAGLQLPVYLGIPGPVKPDKLLR
IAANIGVTDSLRFLRKNLKLSGKLLHGYDASGLMNAYTPHLNESDYGIAGFHIYTFNELV
TLKKTFDRVAT
>A0A1B8GJA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus verrucosus|TrEMBL
MADSPTTDKITDKIAALRQDASYFSLEFFPPKTAMGSTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSKALVDDALKAAKEAGIQNILALRGD
EPRGEYKDALEEGKEGEDEFVWAIDLVKYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
EHDLPYLVDKVQAGADFIMTQLFYDVDAYDNFEKVLRDHSSGAFKSIPIIPGLMPIQSYQ
ILRRTTKLSNAKLPESIIDRLDAVRTDDEMVKKVGVDILAEIVESVKATKQRTKGPKGFH
FYTLNLEKAVAFILERVNLIPSFTPVLTSDAFAVDDITDTIPLPQLLINGERKNRRQSSV
GSGPHNFVIIDREEASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRPDITSIFVQYLNGTLSALPWSDE
PIAAEANLIKDELVKLNQKGWWTIASQPAVNGARSQDEVVGWGPKGGWVFQKAFVELFVP
TSDWARLKPLLEGNGEVSFLAQSASGEFLKSKLDLGPGEEGSETNAVTWGVFPGKEIVSP
TIVEEVSFRAWAEEAWQMWEEWAAVFGKSGEESRRFLDGVAKDGWLVNVIWHDFVGMCKA
KEGRSEEEGYKGLWDVLIEA
>A0A4R9I6S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira noumeaensis|TrEMBL
MHISQVLGKKQTTISFEFFPPKNEEASADLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEETGLTIVSHLTCVGSTKDEIKEILKRYEKSGIHNIMALRGDPPKGQTEFQQT
ENGFAYAGELVGFIKKEFPKMGIGIAGFPEGHPSTPNRLKEIEYLKWKVDQGADYICTQM
FFNNHYFYDFVERCEIAGIKVPIIAGIMPVTSRKGMARMAELSLGTSFPAKLLKSLSRAE
DDSYAENVGIHWATEQVRDLLDNKIAGIHMYTLNKSKATRKIYESLGIRNFDTIG
>A0A1Q7BGI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium 13_2_20CM_2_64_7|TrEMBL
MTTTEDRADPIDAIAEFMADFSLEATRPSAEEVAALAAVAPASTSVYISAVPKRPAQEAI
EAAARLRKAGFEPVPHLAARGFASTRALDDFLARMSGEAGAVRLLVIAGDREEPTGEFRS
AIEVIDGGALQRHGICEIGVAGYPDGHPRLLQQDLDRALADKIRAAESTGLAVHIVTQFC
FDAQAILQWIARLRDFGLEHPVRVGLAGPTNLATLLRYAKRCGVRASAHSLARQAGLVRQ
LFAMSAPDALVRALAQARAERHLGEIAPHFFSFGGLARTARWAEAVAQRHIAFEAGEGFR
VEPPR
>A0A845FTU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomaricurvus sp. HS19|TrEMBL
MSSTDNLRLSFEFFPPKSDEGRTKLLAVRDELQKLQPEFFSVTYGAGGSTRDNTKGIVKT
FKQDGIAVAPHLSFGGDDEATMKALIQEYIDAGVDRIVALRGDMPSGMGGAYQMVYANQL
VAFIREHFGDQLQLEVAAYPEIHPEATSYDSDVGFLKAKFDAGANSALTQYFYSPDAYFY
FIDQCDKAGIDKPIYPGIMPILNYRNLIRFSDNCGADIPRWIRKRLEAFGDDQESVKAFG
LDLVSELCETLLDNGAPGLHFYTMNQVEPTATIVKNLGLTD
>A0A7Z0GM16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nesterenkonia xinjiangensis|TrEMBL
MVRQVRADPLGGPAQREVLSQLLARPRYEVLPLAGIVDDAVAHLPAGATVTVTASPARGP
EPTMQTAEALAAEGFHAVPHLAATQHGEHSLPVTLERLQTAGIQEVFAVGGDAAPGDDRR
GASTAQRGETFDDGEQLLQAVRRLGPELRVGVPGYPEGHLTIPAEALEGSLGRKVEQASC
VVGQLCFDPLTVLSWAGGLQAAGMTLPVFAGLPGAASSAQLMRIAGRIGVGDSLRFLASG
GAGVARRLASLGRYDPTPLAAGLAAAQDGGVVSGLHLYTFNALEETEQWRRRLLARLQEG
DHA
>Q7CZA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium fabrum (strain C58 / ATCC 33970)|TrEMBL
MGWSSFWDNSGADGDVVRSSNILAGWSIEVMPRTAAKIDDFRNILPDGTRVYIAHIDGTP
IADMVSTAKRLHDEGFPVMPHLPARGISGKNELEDWLKRYQGEAGVTQALLLGGGQKQPA
GSFSSSIDMIETGLFDKMGFTHLHLAGHPEGNRDIDSDGSSRGVDQALLWKQDFASRTDA
RLALTTQFAFEAKVVIEWAKRIGNMGVTIPVHVGIAGPTKLQTLIKFAIACGVGPSLKVL
QKRALDLSRLFVPYEPTDFIAELIDHKAANPDSLIEHVHIFPLGGIKPSAEWMKKHASTG
TLANVA
>A0A7L1FIZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sylvia borin|TrEMBL
MVNETQQTGSGSSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDVCVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A5A7ND10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kordiimonadales bacterium JCM 17843|TrEMBL
MSQLRSLSPSLFADRLADTEVSFEFFPPKSEAMETRLWAAIKTLEPLAPRFVSVTYGAGG
STRERTHNTVRRLIRETKLAPAAHLTCVDASREEIDAIVRDYRDSGVRHIVALRGDAPDP
SKGYQPTPGGYANAAELVAGIRAIGDFEISVAAYPECHPESASLVADLDNLKRKVDAGAT
RAITQFFFEADQYFRYLDHARSYGIDVEITPGILPVTNVKQLKRFADGCGASVPRWMADL
FEGLDDLPQTRALVAATVAAEMCRRLQAGGVNSFHFYTLNRDELTYAICHMLGIRSSTHD
TSQEKAG
>A0A5B7SZY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus futsaii|TrEMBL
MTETNPTLSFEVFPPNSQVGVNNLTDTLDQLKGLNPSFISVTASNHKLNYEETTINLAKY
VKDNLHCHTMVHMPAAYVTKTEVRSILNRLEKMNIHQVLALRGDIVEGYIPEKDFKYASD
LTQFIKQEKPDFTVSGACYPEVHPDSKNRVDDIRHLKDKVDSGCDQLITQLFYDNEQFYR
FQEECAIADINVPILAGIMPIVNRKQALHVIENCAARLPKKFINILDKYKDNPVSLKEAG
IAYAVDQIVDLVTNDVSGVHLYTMNKADTAKHIFKNTASLFHLDSVTE
>A0A349NHU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp|TrEMBL
MNISEKLSSDNEGKHFSFEVLPPLKGNGTDILFRTIDKLKDFNPLFINITNHSEEYVYKE
LDNGLIERHRIRRRPGSVAIAAAIQNKYHIPVMPHVICSGATKEDIEYELLDLQFLGLNQ
IFLLRGDKTREDKKFTPVQGGYSHATELIEQVNKFNDGYFVDGTPIKHPGTPFEFGVACY
PEKHEEAPNMEIDMKYLKEKQDAGASFAVTQLFYDNKKFFNFVKRARKMGITIPIIPGIK
PFAKLSQLTVVPKTFHIDFPEELADDALKCKSDEDARQLGIEWTTHQVKELYEYGINNIH
FYTVSAVDSVKEVAHRLL
>V2YFD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ASF500|TrEMBL
MKLCELFGKGRTVFSCEVFPPKRNDPVDSIYQTLDGLKDIRPDFISVTFGAGGSQVNQTT
RDIAALIENRYHIPAMAHLTCVAAGREDVDRLLADLKADGVENVLALRGDVNPDYPPKTD
FKYASDLVSYIRARGDFGVSAACYPEGHLESPDLVSDLRHLKEKVDAGAQHLVSQLFFDN
DDFFRFLERARIAGINVPIEAGIMPVLSKNSIQRMVSMCGASLPSKLTRILARYGDHPDA
LREAGIAYAIDQISDLIAGGVEGIHLYTMNNPDVARQIAGSIDSIRKV
>A0A5P9K0R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga thermotolerans|TrEMBL
MSPIALRPSRQPSCPIRVSFEFFPPKTPEMEATLWSSIERLAPLNPQFVSVTYGAGGSTR
ERTHATVARLVRETRLKPAAHLTCVAASKAEVDSVVRSYWEAGVRHVVALRGDPVGGLGT
AYEPHAEGYQRTCDLVAGIKAIGDFEVSVSAYPEKHPEAASLDADIDVLKEKVDCGADRA
ITQFFFDNDVYFRYLDRVRARGIDIPIVPGIVPVQNFRQTANFAAKAGASIPAWLAARFE
GLEDDVETRKLIAAAVAAEQVIDLVDRGVSEFHFYTMNRADLVYAICRLLGLRGEAERAA
A
>A9CIN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium fabrum (strain C58 / ATCC 33970)|TrEMBL
MVTKRIMLKLPDISAASLIPASIEASPAQVLGPASLAGIFPRGVRVYLTDTGAASQEKLV
DAATHLRNLGYEPVPHLAARRIPSRVEFEEQVKRLAGEADVTDVLVVGGGVDRPAGPFAS
SMDMLSSGIFDRYGIKKIAIAGHPEGSPDFSEETAIAALRLKRDFGERSDAAMRIVTQFG
FDPARFIAWAEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LARGHSPDSIVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVSRGSWQTRDAGRPAP
ADSMAG
>A0A0C2QAP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scytonema tolypothrichoides VB-61278|TrEMBL
MLDTINPTALTSFRTAAKAGQFLITAEVAPPKGGNPEHMITMAATLKGRVHAVNITDGSR
AVLRMCSLVASAILLQNGIEPICQIACRDRNRIAIQADLMGAHALGIHNILALTGDPVKA
GDHPDAKGVFDLEGVRLLQLIHKLNQGVDCNEKPLTDGALDLFPGAAVDPQCASWSGLQS
RFERKLAAGAQFFQSQLITDFERLEKFMDKIAAGCDKPILAGIFLLKSAKNAQFINRCVP
GVNIPDHIIDRLAQAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIVPILDMAGV
GVVNK
>A0A1V3R672|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. A45|TrEMBL
MKVTEHIEKAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVD
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKEGGNNYASDLVSQIYQLNNGKYLHDVMDIDNKADFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLINAVDKCKNNVEIRQVGIEWAIQQSIELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A375FRX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus oxalaticus|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVRAGADSAITQYFYNADAYFRFVD
DVRAQGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A419YFS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TLI_171|TrEMBL
MALGIPSTRSDRAQTVRDLLAAGDRSFSFEFMPPRNEEGERKLWDAIRRVESLDPNFVCM
TYGAGGSSRGRTVNLVGRIATETTLTPVAHLTAVDHSVAELRNIIGQYADEGVRNVLAVR
GDPPGDLMGEWVRHPEGVTYAYELVELIKGIGDFCVGVAAFPQMHPRSENWDEDIRHFVA
KCRAGADYAITQMFFEVEDYLRLRDRVAAAGCETPIIPEIMPLTNIRQLVRFPQLSGSDF
PPDFRQKVESVADDPVAVRAAGLEHATAMAERLLAEGAPGLHFITLNHSTSTLEIYQNLG
LHQR
>A0A8H6CJW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Letharia lupina|TrEMBL
MHIKDKLAEAERSRKPVFSFEFFPPKTALGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRS
DLTCEMVNTAQTIYGLETCMHLTCTDMEKQKVDDALKSAYSAGCSNILALRGDPPRENEK
WQAVEGGFRYARDLVEYIKARYGDHFDIGVAGYPEGCDDQQDQEILLEHLKEKVDAGGTF
IVTQMFYDVDLFLSWVEKVRARGISVPIVPGIMPIQTHAAFLRRAAWSKCHIPQKWADAL
EPIKNDDAQVREVGKGLVAEMCRKIIDAGIMQLHFYTMNLAQATRMVLEELDLVPKDGTP
NTRILPWRQSLGLNRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDARSPAFGELDA
YDIGLKGTNEQNVKLWGKPESVRDVANIFIRFLEGNLQSLPWSEAPITSEAEAIRPELIN
LNRRGLLTITSQPSVNGVKSTHPVHGWGPKGGYVYQKTYVELLISPQLIPELIARIERSS
TMTYYAVTKGGDLSTNAPSEGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAYHLGADW
AKCYAASSPSRQLIDKIMDTWYLINIVDNDFHQTHAIFSLFEGLEVEDLDKPSVNGHQSN
DHCPTANGAPIEVHN
>A0A3Q9R0Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neobacillus mesonae|TrEMBL
MNLLEKLQQEILIADGAMGTLLYSYGTGSCFEELNLSHPEQIQTIHQAYIDAGADVIQTN
TYAANYLKLQRYGLEDSVKEINSAAVRHAKAAAKSQTFVLGTMGGNRGIKPESITIEEIK
RSFREQLYCLLLEGVDGLLLETFYDLEELETVLAIARKETKLPIIAQVSIQEPGVLQNRT
PINEALKSLEGLGADVVGLNCRLGPYHMLAALEQIELPKHALLSAYPNASLPAYTDGKFH
YEGDADYFRKSAQSFRNQGVRLLGGCCGTTPEHIRAFATGLKDRTPIVEKVVKLERKQIS
IEEHEPKREYEPLQEIVKKRSSVIVELDPPRKLNTDKFFEGARAFKEAGIDALTLADNSL
ATVRISNESLGYLVKQELGMRPLIHIACRDRNIIGLQSHLMGLHTLGMNDVLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGAKTAFSVAAAFNPNVRSVEKAVK
RLEKKISFGADYFISQPVFSEEKLLEVYEHTKHLETPIYIGLMPLTSSKNAEFLHNEVPG
IKIADSIRERMFALNDNPLQAAREGVEITKQLIDAALDLFNGIYLITPFLRYELTLELAL
YTKERARKLRGNSYVETTIY
>A0A845QF48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyruvatibacter mobilis|TrEMBL
MAPTSPSTPDTAATGGQGSGIEVSFEFFPPKTEKMEQTLWASIEKLAPLNPRFVSVTYGA
GGSTRDRTHATVKRIVNETSLKPAAHLTCVEATREEVDDVIRSYWEAGVRHIVALRGDPP
SGIGAKYVPHEGGYANAAELAAGISKIAPFEISVGCYPEKHPESASFEADLDLLKAKIDG
GASRAISQFFVEPDTFLRYVDRARSAGIDIPIVPGIMPVGNVAGFLRMAEATGTSVPAWF
RDRFEGLDDDPQTRALIALSVAADQVRQLADQGIRQFHIYTLNKAETAYALAHLLGVRPS
KPLAA
>M1C551|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solanum tuberosum|TrEMBL
MKVIEKIQESVKDDRVVFSFEFFPPKTEDGVDNLFERMERMVSHNPSFCDITWGAGGSTA
DLTLEISNRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPATGLATLETYENELAYLK
QKVDAGADLIVTQLFYDTDNFLKFVSDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTR
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKIMASGIKTLHLYTLNMEKSALAILMNL
GLIEESKISRPLPWRRPTNVFRIKEDVRPIFWANRPKSYISRTIGWDEFPHGRWGNAKNP
SYGALSDYQFMRARSRDKKLQEEWAIALNSVEDIYERFMNYCLGKLRSCPWSELDGLQAE
TKIIDDHLGNINSKGFLTINSQPSVNGAKSDAPLVGKFDA
>A0A6L5EE40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter telavivensis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGSGKPDMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A6G2YBX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8382|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRAELRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWISHPDGLDYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIGHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATELCARLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>A0A2H5Z4V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR28|TrEMBL
MAHPFLERLQRGPLLADGAMGTQLYERGVRLEQCFEAVNLREPDLVVAIHRDYILAGAEL
IETNTFGANRMKLESHGLGERVRDVNRRAVRLAREAREITGIPVLIAGAVGPSGRILAPI
GTVAPETIRDVFREQIEALLEGGVDLLIFETFSQLEELRQAILAAREVSDLPLVAQMTFA
ADGRTMAGHTPDVVVQSLTELGVDAIGVNCSVGPRPMLAVLRDMVAANTGNIPLSAMPNA
GWPTVLGDRVIFGSSPDYFAEFAQEALELGVRILGGCCGTTPNHIAAMRRVLDEQRGTSV
SSGAAIRLEERVRPVTVLAPEGPTRLKQKLGREFIISVEIDPPKGLNPQKAIDGARILRQ
SGVEFINVADSPMARVRLSALGLCYLLQHEVGIETILHLTTRDRNLMGLQSDLLGAHALG
VRNILALTGDPPTLGDYPHATPVYDVDSIGLVRILTNFNNGMDAGGASIGQQASFTIGVA
CDPTRSDLDRELERLHAKLAAGAHFIMTQPVFDLDTWLTFVRKYEERYGPLGVPVLLGIL
PLQSYRHAVFLHNEVPGITLTEEALERMRRAGANGRAEGVAMARDLVARAYEVVEGIYIM
PSFGRYEVAVEVVESLPQNRVRRVTS
>A0A7C6L4A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrimonas sp|TrEMBL
MKILELIDQTSKPVFSFELLPPLKGNSIKQVFGTIDRLKEFGPKYINITTHHSENIYKEE
EDGTIRKVNVRRRPGSVAIAAAIQNKYGIRAVPHIISQGFSREETEYALIDLSFLGVTDL
LLLRGDTKKLDADQRNVDSHPYATGLQEQVNNFNKGIAFDGSAFPVPETPFTYGMACYPE
KHEESPNMESEIHYTKMKAQNGADYLVTQMFFDNQKYFDFVDRCRAEGITIPIVPGIKPI
HLKNQLNVLPKIFRTEIPEDLERELRKCKTDADAVEVGVEWCLLQSKELARRGVPGIHFY
ALGATESIYRVAKEVY
>C2MQP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus m1293|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A435ERU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7D.F.Ca.US.004.01.2.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETAIPAAAHLTCVG
>A0A1C3IYA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio atlanticus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A3N2D9K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salana multivorans|TrEMBL
MTTSELYRPPRPTISYELYPPRTPKGEAQVWETITRLAEGDADYFSVTYGASGSTAERSQ
ALVARILAETTVPVIAHLTCVGRSRAELRAVVEAFLDAGVRDFLALRGDAPQGETEWTPA
PDGFSRASDLVELIREVEAERFGARASSGLARLVAHRGQHPRVSIAVAAYPGYETSAAVA
AGEDPAVGGAEAGAVGAAPATRRYACRADELAALRAKQDAGADFAITQLFFDAEAYRELQ
QAAREAGVTIPLVPGILPLTDPARVRKLCALNDIPEPTALLAELDAAATRDEATRIGLRA
TARLAREVLEAGAPGLHLYTFNQHGGVSALLDEVLAPA
>A0A1U9UIT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus necator|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVKAGADSAITQYFYNADAYFRFVD
DVRALGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLEGFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A367PRB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus necator|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAVLQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVKAGADSAITQYFYNADAYFRFVD
DVRAQGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A1R4GX83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter piechaudii|TrEMBL
MSKPQFSFEFFPTKTDDGITKLYQTFDTLNELAPSYFSVTYGAGGTTRERTLGIVEALKN
RANTPIAPHISCIGDNKSQIAELLDFYKSIGISRMVALRGDLPSGQVGMGELPFAVDLVR
FIREHSGDHFQIEVAAYPEMHPQAISFEQDIQNLINKFEAGANSAITQFFYNAESYLYLR
DALEKRGVDTDKHRLVAGIMPIINASNLIRFADSCGADIPRFIRKQLADYGDDRKAIREF
GFEVVHRLCEVLIAEGVPALHFYTMNRVEPNKRLVQSLGLTSSSTQA
>A0A0N1G7C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium OK006|TrEMBL
MLGTGKATYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSVTYGAGGSTRAGTVKETEQ
IVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVPHPQGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDVDVAHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVVAAGCTTPVIPEVMPVTSVKMLERLPKLSNASFPDVLKERILTAKDDPAAV
RSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGLHHPQQA
>A0A1Q5GHB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB01580|TrEMBL
MRELLATGKPSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKA
TQEIAADTTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVRGDPPGDPMAEWVEHP
RGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWDTDIRHFVDKCRAGADYAITQMFF
NPDDYVRMRDRVVAAGCETPIIPEVMPLTSVKQLDRFAQLSNASFPSSLKERILAVKDDP
AAVRSIGIDFATEFCARLLSEGVPGLHFITLNNSTATLEIHENLGLHKQL
>M6H718|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Zanoni str. LT2156|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFL
>A0A7Y4YAS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferruginibacter sp|TrEMBL
MKVIDHINQAKDTLVSFEILPPLKGKGIQSLYKHLDPLMEFKPSFINVTYHRSEHVFKKN
ADGSFAKVVVRKRPGTESICAAIMNKYSVDTVPHLICGGFNINETEDALINLHYLGIDNV
LVLRGDAAKNESAFEPDPAGHKYASDLLQQVVNLNAGVYLEEDLKNSSNTKFCIGVAGYP
EKHFEAPNMDSDLKYLKMKVDLGADYIVTQMFYDNEKYYAFVKACRDMGINVPIIPGLKP
IYTKKQLTMLPKVFHIDLPAALSNEVAKCKTDEDVEKVGAEWLLHQSRELKKFGVPVLHY
YTLGRPQIIADVVKQLV
>B5YA71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyoglomus thermophilum (strain ATCC 35947 / DSM 3960 / H-6-12)|TrEMBL
MNFEERLKSGKFVITAEVSPPRGVDVSSFIEKTLLLKDRVDAVNVTDFQNVGVRITSLVG
SYLLLREGMEPIFQITARDRNRVAISGELLSAYTLGIRNVLVLTGDYTTTGIAKSAKPVF
DLDATNILVVAKRLEDGEDFSGKKLNKNPDFFLGAVFNPNLVPLEIEILKLLKKKKAGAE
FFQTQLFFDLSVMERVRERVGNEIKIIAGVTIFKSIEMLEYMMSSVPGIKIPTEILDMFR
NTKDIKSLSIEFCAEFCSKLKESKLLDGIHFLASRPSDIIKVLDLLNW
>A0A7J7H2K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Camellia sinensis|TrEMBL
MKVIEKIRESEGGDKVVFSFEFFPPKTEDGVDNLFERMERMVIHNPSFCDITWGAGGSTA
DLTLEISNRMQNMVCVETMMHLTCTNMPVDKIDHALDSIRSNGIQNVLALRGDPPHGQDK
FVQVHGGFACALDLVKHIRSKYGDYFGITVAGYPEGHPDVIQSDGLATPEAYQNDLEYLK
RKVDAGADLIITQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFIRMTGFCRTK
IPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKIMANGIKTLHIYTLNMEKSALAILMNL
GLIEETKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWEQYPHGRWGYSHSA
SYGALTDYQFMRPRARDKKLHDEWAVPLKNVEDIHEKFMKYCLGKLRSSPWSELDGLQPE
TKIINEQLVNMNSKGFLTINSQPAVNGANSDSPSVGWGGAGGYVYQKAYVEFFCSRDKLN
ALVEKCSAFPYVTYMAVNKDGIWISKVGQTDVNAVTWGVFPGKEIIQPTVVDPSSFMVWK
DEAFEIWSRGWAQLYPEADPSRNLLEEVQSSYFLVSLVDNDYISGDLFAVFKDF
>A0A256ZWY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon ex4484_162|TrEMBL
MSYRSNLERILMNRWFAVTAEICPPKGSDPSRIKQKGDILRGCADAFNVTDNQTAVVRMS
SIAGSVILSNMGLEPIMQITCRDRNRIALQSEVLGAYAVGIRNMLFITGDHQSFGNHPSA
KGVYDLDSIQLIHVVKNMRDNGLFQNGEEILFGKPDIFIGAAANPFVDPYEMGVDRLEKK
ITAGTDFIQTQSVFNLERFNEWMDEVRARGLDKKISILAGVTPLKSLKMTMRMKYHVPGV
DVPDEIVNRMKNTRDQKKEGYEIAVEILREIRRIRGVHGVHITALFWEDIIPFLVKNTGL
FPRP
>A0A7Y0QJE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas fimi|TrEMBL
MTIADGCTTTTTRATTRPTVSFELFPPRTPQSTDQLWTTIEALAAVRPDFISVTYGASGS
TRQTTRELVHRLLERTPVLPIAHLTCVGASRSDVATVVNEFLDEGVRNFLALRGDPPQDQ
PDWTPHPDGLSRASELVELIREVETARCGSSASEALRGAARKLSVAVAAFPHGNPKAGSS
RAQDLRALLAKQEAGADFAITQVFFDPADYLDLVRDARAVGVTIPIVAGVIPTTDPGRLL
RVEALTGVQVPSALLARLASTDSPVERHRIGIRASVDLANAVLDGGAPGLHVYTFNKHEA
ALDLLEGAHLGGGAPTAPDQASGPRVSTDTMDYVTI
>A0A6F8YPN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytohabitans suffuscus|TrEMBL
MALGLPSVLPGGSQPSIGDLIAGPVPTFSFEFFPPKTAEGQPLLWQAIRELEPLRPSFVS
ITYGAGGTTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAV
RGDPPGNPMGEWVRHPDGVMYAADLVRLLKESGDFCVGVAAFPYKHPRSGDIAADTARFV
EKCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPIVPGVMPVTRMATIERSEQLSGAP
FPPALLERFERVAGDAEAVRRLGVEQCSEMCARLLDEGVPGIHFITLNRSTATREVWQNL
PAGARV
>A0A2N1TZG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Riflebacteria bacterium HGW-Riflebacteria-1|TrEMBL
MCPNLTTGEKQLQDFREFIEKNIVIFDGAMGTRLYEKGVYINRVYDELNLSQPALIQEVH
REYLAAGAMVLETNSFGANRFKLEPHGLADKLEVINFQAAKLAREAAGDNAWVAGSIGPL
GIRIEPWGKTSVEEAEEAFTEQARGLLAGGVDIFILETFFDINEIHQAIKAVRKLSDKPI
IASMTINEDGNALYGTTVDVFTPKLESWGADVIGLNCSVGPKTMYDAIEKMRALTRLNLI
AQPNAGLPRVVDGRMIYLCNPEYFGEYARRFFQLGVRMVGGCCGTTPEHIKWVANSAKAL
SPGGKGAILHQFRQVESVEEIVEVVPLSQKSALGKKLAENKFVVTAELTPPKGCDPEQVI
RRAQQLKEAGIDAINIPDGPRASARLSPLAMSLLIEQKVGIETILHYCCRDRNILGIQSD
LLGAYAIGLRNILAITGDPPKVGNYPQATAVFDIDAIGLVNVIHRLNHGRDLGNNAIGRP
TGFVCGVGANPGAIDLDLEVSRFEWKVDAGAEYAITQPVFDVELLERFLERISHVRIPVF
AGIWPLASLKNAEFMNNEVPGASVPEPLLQRMRKADTIEAQREEGILIAREALERVRKIV
NGVQVSVPFGRVESVLKVIEVLG
>A0A1C3FDS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfovibrio sp. N1|TrEMBL
MEGEIVITVEMTPPKGPDVTSLVEKLKELKFLTDAVNFTDNPSAKMRMCSMSACKISLDL
GFEPVLQMSCRDRNRIAIQSDLLGAHALGIRNLLVMTGDHPVWGDHKEAKAVYDIDSSLL
IKLVNNLNNGLDINGNKLNGNTDFFIGAVVNPNVDPLLPQLKRFEQKLKMGAQFFQTQMI
FELEKLEQFMDFANKFNNVKIIVGIIIIKTKKMLQFIAEKIPGVVVPQWLIDKVNTLNDN
DVEKFGIEFA
>A0A1Z9GUL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium TMED154|TrEMBL
GAELLVSQFFLVNEFFLKWRDRLHRGGVRVPIIPGLLLPSSAEALFRMSKLCGVSIPGSL
RAKLERFADDPGALKEIGWNHLEAQTESLLREGIEGVHLYALNRLETVRRFSQMIQPVSG
RHDTYPENPGKYSIAENSKIPMTA
>A0A069SH64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus str. 3975 RP4|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKDGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVEAGADYVVTQMFYDNRKYVDFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAMKCKDDKEARALGIEWCINQCRELIAYGVPGIHF
YTVGAVDNVKEVATAVY
>A0A412T0L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF16-8|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRSHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDASASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>X5RYQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSJC265A00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A5M3XTT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acrocarpospora pleiomorpha|TrEMBL
MSGLRAALASDRVVVTAEIGPPRDADPDAIARKAAALRGWVDAANVTDNQGASVRMSSLA
GSVLVQRAGVDPVMQLTCRDRNRIALQSDLIGAAALGIRNVLLLTGDHPALGDHPDAKPV
FDLDGVQLVWTARTLRDDGTLLSGKPLATRPSWLIGTVENPFAAPMALRARRLAKKVAAG
AEFVQTQYVFDVDAFARWVAQLREEGVTERCAVIAGVGPIRSLRMLAFLTGSVPGVHVPA
ELERRLRGVPERRVAEEGLNACVETIQALVGIPGVRGVHLMVFGHDDEVPDLVRRAGIRP
AVAALQEGRQ
>A0A2H5XIP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR18|TrEMBL
MKVIEILEQAAGPLISYEIIPPRRGGSLEEVMAVVAELMPFDPPFIDVTSHAAEVEYEPL
PDGTLRPRIKRKRPGTLSICAAIKSRFGVETVPHLLCHGFTREETEDALIELHYLGIQNV
MALRGDSPGYRKPIPPDRTVNLYAVDLVQQIANMNRGIYLEPLEDAVATDFCIGVAGYPE
KHYEAPNLTWDILNLKRKIEAGAHYVTTQMFFDNRHYFRFVERCREVGITVPIIPGLKIL
TSKQHLQLLPSRFHIEIPEALAAEVEAAKPEHVPEIGIAWALRQAEELLEAGVPCLHFYI
MLRADYVRRVVEALRKMA
>A0A2S6YD03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis pv. begoniae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGS
>A0A5C8CGE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira aalborgi|TrEMBL
MNSVENFINKLENEKEFTFTLEVTPQAKSDLGYLVEKIKSSNIEKYIDAFIIPDSPFANL
KISPILSSLQLSQRLKTEKPFIITQTMRDKNSIALQNDLIGANYFDIRMVLALTGDPVVN
GNQKQAKGVFEGNSELLIRIIKNLNEGKSAGNFIFKEPLKKIYPFCSINSYSKNYEMLKV
RLSKKTASGVKAIFTQPIYEVETLKKFLNWIDEMPLKEMKLKEKPILFPGFFPVLNYKTA
YFIYYKLPGAYIPEEWLNKLKDASEKSAEEEKKVAFELSSNLFKDMLSVCKKMHIMSMNN
YDFVADLLKHI
>A0A2D4BX93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pythium insidiosum|TrEMBL
MKIIDKIHASTDKGEVFYSFEFFPPKTAAGVDNLYTRMDRMASLEPLFCDMTWGAGGSSA
QLTLELCANAQKFSGLDMLMHMTCTNMAEQDLRAALDRAKDAGIQNILALRGDAARGAAS
FDECDRGFSHASDLVAYIREHYGDHFCVGVAGYPEGHLEAPDLATDIQHLKRKACRAAGI
TCPIIPGIMPIQNYSGFVRMTSFCNTAVPEDIKAALEPIKDNDEAVKDYGVELGIRMCRE
LLDAGVPGLHFYTLNLERSVRRILDGLDVLSSKATRRELPWRPSKLAKRASESVRPIYWS
NRPKSYLQRTAAWDEFPNGRWGNSESPAFGDLSESHYMHCALSLQDRKAMWGEAPMSKDE
IHHTFVKYVRGEIKALPWCDAALHLETKSIQDELERINAAGFLTVNSQPRVNAAPSDDPV
FGWGGPGGHVYQKAYVECFVSPENMKKIIENAARMRYIQYHAVDFRGHSYSNAGKSAIAV
TWGVFPNKEVLQPTIVDSNSFLAWKDEAFSLWLKEWASIYDDDSRAAEIIHEIHDTYFLV
SIVDNDFIRGNIWEIFGAPPLLALSFPGSMTVVMADAGVPTSQARVLRGHSGPVNAVRFN
DKGTYVMTCGQDKSIRLWNPHRDGLEQRGEGLLVKTYHGRHGYDVQDVAIAQDNAQFASC
GRDKAVFVWDVPTGKVIRKFEGHEHSINCVRYNADSTVLLSGSYDKTVRAWDIRARNSFR
PIQVLDEFKDSVTSLVVTGHEIIAGCVDGTVRTFDLRAGVVYRDHIEEPVVSIARSPDGS
QLLASALDGSLRLIDRKSGAEMKSYRGHRVDAYKIDCAFSSDGAHVLSGSEDGRVHYWDL
VHGRHQQFLAHGKPLRAMAFHPEDAMLITACVAGSVKVWLPPTT
>A0A6G8CSD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diaphorobacter sp. HDW4A|TrEMBL
MTKSQNQNKLPVSFEFFPPKTPEGAQKLRTVRAQLYERKPEFCSVTYGAGGSTQEGTFNA
VKEILAEGVDAASHFSCIGATRDSVREQLALLKVMGVRRLVALRGDLPSGYGMGGEFHYA
SDLVSFIREETGDYFHIEVAAYPEVHPQARSADADLQAYVTKVKAGANSAITQYFFNADA
YFRFVDDTRKLGVDVPVVPGIMPILGASQLMRFSDACGAEIPRWIRLRLQGYGDDIDSIR
AFGLDVIANLCEQLIQGGAPSIHFYTMNQSAATLELCKRIGV
>A0A6G4W8S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium camelthorni|TrEMBL
MNQFRFSRRPDIGDRIRVSFEFFPPKTDEMEARLWNTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTVKRILTDTSISAAAHLTCVGASRDEVNTVIREYDALGIKRFVALRGDPASGVGQ
AYTPYPGGYENGAELVAGLRAISDFDISVAAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDIYERYVERVRRAGIYIPIVPGVQPVHNFRQVANFSSRAGAHVPAWLAERFE
GLDDDPQTHALVASAVAAEQVMDLVERGVSDFHFYTMNRADLVVAICHMIGIRAHDTTAA
AEGFAAA
>A0A7X6GKR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium R_SAG4|TrEMBL
MTTPEISFEFFPPKNLEASFRLWDTVQSLAPLAPRFVSVTYGAGGTTRELTRDAVTTLHK
NSGLKVAAHLTCVSATRQETLDIADQYAAAGITDIVALRGDPPKEQGRFTPTEDGFGSSV
ELIEALAAKGKFNLRVGAYPESHPEAASQQANVEWLKRKLDAGADEALTQFFFEAESFFR
FRDACSKAGIDTDRITPGILPIENWKGVRRFAEACGTTIPAWLDEAFEKAQRDDRCDLLA
TALCSELCTELLDGGVKKLHFYTLNRPELTRDVCHALGVKSKARLQNVA
>A0A2D4CI31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pythium insidiosum|TrEMBL
MELLVWHASLGCDDEQASDTETLSRLLYAFDSQAPSSPPPSAWQLQALNLMQALVTFSCG
LRERRRPDDSPSPSTSVARSGISVTLARRRVFIREVEPQIFMSLSVDAADGDTELRDAHN
ALLHDLYDTFRLFFGSFHRRLDRLEQQTPETSAFPDGMALLRQLQSLRKQQRKLQIAREL
EQDEVHTRKDDGDAAAELQLQHLKTQIDALEAVAPTRRLWSDCHALFPTLLRSLVHAAAP
LNVFHELQGLTYFPMDETTFLAVQTFVNSLVAELDGVVHDVALFFKGNVLWRSMPSLRSL
HVLQRFLRLREQHGMTVDLWDPPHRQEDDRVASTLWMPRDYDDAFLPIWASKTAYAELTI
ARHQASSASASAASSSRRSLHRQSSSTLNALIADLVSQLDLSTESASSPRQRQLKRNDSN
GSGSGRGGLFSFDKAEQLVLRRTQRFRANTACYRNRGFLTTSGYFLATWELAKNSDSDTF
WCPQVYALGDTDDATGRDDARRVIVWHEAELTLLLLVPSDDSVSLSLMERIETTLERLDA
ARLAATIATRFHAMTTSHNAKREKAAATAAPPFVYLNRANLAFTAQHIPRLVKTRDDSSE
SLFPRPVGLWASYVPSHVLSIMASLNATIKSGQAAHGDVELSVKTMSDGWVVMRHTHSTQ
RQLVVFLDTKSSCVPDVQDAIEELLQQQFGNVFFISLLSLLPASTDRPTMGKIIDAILAT
YAGSSDGAASTSTSSSAGAGAARPTVSFEFFPAKTEDGVFNLLNRVEEMGFSLRPTFVTL
TWRSAFKDEKLWLRIGAHIQNEFQLDVLLHLTCHLPREELRRVLHAARAAGIRNILALRG
DPPIGAERWKPVPDGLNNAVDLIRLIREEHGDYFCIACAGYPEVHTESWNHPDLPPSKEA
RLLDLQRLKMKQDAGADFIITQFFFDTDNLLQWVKDCRELGISIPILPGYLPIQNYNSFL
KFTSWCKTRVPHDVLAALDKIKNDDAAVRRYGTELAIQTCKKILDAGIKSLHFYTMNLAS
TVTAVLDGLELIPARAQRDLPWQSTLRRTNSNGDRTEQVRPIFWSNRQASYIARTSAWDE
FPNGRWGDRASPAYGDLSEYYLAFKRPKVNRRELWGSPQSHEDVWQVFVRFIDG
>K6S7E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus casei UW4|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPHACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFPGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>K9QIM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. PCC 7107|TrEMBL
MCMYHTHSPTVSLFQKAAQAGEFLVTAEVAPPKGGNPAHTIEMAATLKGRVHAVNITDGS
RAVLRMSSLVASAILLQNGIEPVCQMACRDRNRIALQADLMGAHALGIRNILALTGDPVK
AGDHPDAKAVFDLEAVRLLQLIQKMNQGVDCNDKPLTDGATDLFVGAAVDPQCASWSGLQ
SRFERKIVAGAQFFQSQLITDFERLEKFMDKIASVHKKPILAGIFLLKSAKNAQFINRCV
PGVNIPEHIIDRLAKAKDPLEEGVKIAAEQVQIAKQLCHGVHIMAVKREDLIPQILNLAG
VKPVNLVVAK
>E7N6P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. oral taxon 171 str. F0337|TrEMBL
MPTVSLELFPPRPGKAASATWGRIDRLLATGPDFVSVTYRPTFVSDPAGGNSDGGHEGSP
SKPAAGRCDVAPRVRVAQERTNPSECVLAHVLESSTIPLMAHLTCIGYCKQEAVDIVTRF
LRMGVRRFLALRGDPPAGTRADDVAGELRHADDLVRVIREVEADFFGDGRRHVTIAVAAY
PAANDHIEAIEVLAAKQAAGADLAITQVFYDAADYVALTNAASYAGVSIPILPGVIPLTD
LRRLTRLEALTGVRVPESLRSSLGSASGATLVERGIGATLDLATALLRAGAPGLHLYTFN
RTRPALDVISHLRLGGILAGAAPDREVRDAVDRGYLQATPGRGPSFLRCGTPGAALSSRH
PVQPHTTITKENA
>A0A2H9UKC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 5347|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAADLVR
FIREYSGDHFKIEVAAYPEMHPQAESFDQDIQHFVEKVQAGANAALTQFFFNPDAYFYFV
ERIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>B8L0Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. SKA14|TrEMBL
MPAPAAAARAMTAISFEFYPPKTDEQRNQLDRAADKLKDYGPEYVSCTFGAGGSTLSYTS
ETVRHLNQHHGFEAAPHLSCVGGTRQEIRELLKLYRAIGCDRLVALRGDLPSGMGFPGDM
RYAAELIAFIRAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYN
PDAYFHFVDAVQRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRRMQAYGDDVD
SVRAFGTEVVAKLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQL
>A0A2T0RWP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliiruegeria haliotis|TrEMBL
MTVPNVSFEFFPPRSVEASFRLHDTVQALAPLQPEFVSVTYGAGGTTRRLTHEAVSAIHS
TTELRVAAHLTCVDATRQETLAIAKSYAEAGVTDIVALRGDPPKGATRFEPHPDGFRDSC
ELISALKASGDFTIRVGAYPDRHPEAASDTSDVEWLKRKIDAGADGAITQFFFEAETFFR
FRDACAAAGIDAPILPGILPIEHWANTKRFATRCGASIPGWLDDAFAHAIRDDREELLAI
AVATELCSELIDGGVEHLHFYTLNKPHLTHDICHALGITQQAALENVA
>A0A4Q1URN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium erdmanii|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVGRILNETSLTPAAHMTCVDAARHQVDAVIQEFAAMGVKRFVALRGDPAAGVGA
AYRPHPDGYANGAELVGAMKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>G2MWP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter wiegelii Rt8.B1|TrEMBL
MLKNENLCTKLKKRKFVVTAEISTPKGVDITKTIEEARKLKGIVDALNITDCPMANMRMS
PIAVAHLLQDHLNIEAIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDDPSRGDTPQ
AKGVYDVDSVGLLKIISAFNRGYDYNGNKLDSPTEFCAGTTANPNDLRDEALEKLKVKIE
AGAEFIQTQPVYDEEILFKFIEKIKNFNVPLLIGILPLKSYKMAVNLNEKVPGIDIPEKV
LERLKDGGREEGINIAVEFIKRIRSEVAGIHIMPLGSTNVVLEIISRVDDLVCDFAENNV
QMN
>A0A0M8WV27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL B-1140|TrEMBL
MTTFSFEFFPPKTAAGERTLWQAIRRVETLRPDFVSVTYGAGGSSRDRTIEITRRIAAET
TLRPVAHLTAVGHSVAELRQIIGAYADAGIKDVLVLRGDPPGDPRGPWVPHPDGFTHAYQ
LVELVRSLGDFTIGVAAFPERHPRSPDWDTDIRHFVAKCRAGADYAITQMFFDVEDYLRL
RDRVAAAGCDIPIVPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAARDDRAAGHRIGV
EYATAMAGRLLAEGAPGLHYITLNRSTAALDIHRDVITSRSIRVA
>A0A2H0PK04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG11_big_fil_rev_8_21_14_0_20_45_16|TrEMBL
MMKSNEFGFKQDVKIIDLLKSQKFTFSAEIIPPRNGVEQVKVLDQIKVLISAGAEFFSVT
KGAGGSLRGGSLPISQAIKDQFGVPCIAHFTCRDMTPQEVENQLMDHHYFGIRNILALRG
DPPTDQPDWRPHSESLRYAYQLIRQIRELNEGRFLPRPGARSDQNQVATDFCIGAAVYPE
HPVASEKIEFLKMKVDEGAEYGITQMIFDASVYAQFLEDCAKQGLQVPILPGSLILRSQA
QAHRMMKRFGIQVSAKIMNKLPAEREANGVGRVVDLFLEYLEDLKRVGAPGVHLFVMSDI
EASSGALEKMKLLEVGDG
>A0A1G0ZBU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_44_16|TrEMBL
MSDKLKEKLCNQIVIFDGAMGTEIYKRNFFVNISFESLCVSSPKIISEIHKSYYDAGAEV
LTTNSYNANFNKLSYYGLSDKVKEINTAAVKLAKESGGTDTLIAGSVGPIGDISYNSGIT
DERIVEILTEHIQALQDAGADFIIFETTSSLIDTEYAFRAINNGPSLPYVISFSLDRNCE
TAKGEPVAKLLQVLNGNGRKPTALGLNCGEGAEGMLASLEKFIPLVDYPVIAQPNAGIPK
NVDNRMLYMTNPEYLTTYAKRYVDLGARAVGGCCGTGPDHIKDIARSIKPLGKSEFSSKL
RIIEHDVPLKEPMPTASKSKFGKKLASGEWITSVEILPPHGYMLKQTIEKAILCKNAGVD
AINIPDGPRASSRISPLVTALQIQREADIETVLHFCCRDKNLIGMQADILGCSCLGLNNV
LFITGDPPKLGDYPFASAVFDVDSIGMVKIQDRLNRGVDLGGKPIDPPTAILIGVGADPN
AIDMERELRRTREKVEAGAEFIITQPVFAVEPLLAFLDKISYLKTPVIAGIFPLASFRNA
EFMKNEVPGVVVPDEIMKRMAGAETKEAQRQEGIKIARESIEKIKDGIQGIQVSAPLGNV
STAIEVIKSK
>A0A837PSU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. oryzae|TrEMBL
MGSMSQDRRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVL
QLENEVKVPAAPHLSCVGDGKDDLRNLLAQYREAGIKRIVALRGDLPSGMGMASGELRHA
NDLVTFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADS
YFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQ
AFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1M6QEH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforamulus aeronauticus DSM 10349|TrEMBL
MIRAYLKDNILITDGAMGTYYAEITGKYDILPEMANLDEAETIERIHHEYIEAGAKLIKT
NTFSANSIGMDVSRAEIEKVISAGIEIANRVALGKNVFVAASIGPIPDMVGKTDMDPEVI
LDEYKFVVDVFLKKNAKIFIFETFSDTRYLQEITQYIKEKDNSVFIVTQFATTPEGFTRK
ALSIDSIITLARSCNSIDAYGFNCGVGPTHIFNNLKDKLFAEDIVAVAPNAGYPEIVRGR
TVYINNPEYFAERMREISGLGAKILGGCCGTTPAHIKKMAELIHSGKVDSFSRPAVSPKP
NVLAGRKNRNDFAEKLKRDQFVIAVELDPPFNADPQTIINNARICKESGVDIVTIADSPM
GRARVDSMMLAAKIKREAGIDVIPHICCRDKNSNALKSALLAGYIEDIRNVLAVTGDPIA
ESDKGEIKGVFNLNSLKLMELMSSMNKDVFSEEPITIGGALNLNAMRPAGEIQRMLKKAE
RGATFFLTQPIFDNNVIDFLSQINPKDNVKILGGIMPLVSYRNAQFLNNEVAGIRIPESI
INKFDPTMEKEDAERLGIEIALEIAEKMKNVVNGFYFITPFNRVRMITKIINRLGM
>A0A6L6F712|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia sp. wls1938|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSAEMEQTLWKSIDRLKVLKPNFVSVTY
GANSGERDRTHSIIKDIKDKTGLVAAPHLTCIDASPDELKTIARDYWNNGIRHIVALRGD
LPDNSRKPDMYAEHLVELLKTEADFDISVAAYPEVHPEAKSAQADLINLKKKIEAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKITNVRIPSWMNRMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPK
>A0A2E8ZCK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp|TrEMBL
MTIDDRVPLYADLAGDARVSFEFFPPKTEKMEAQLWSAIETLAPLAPRFVSVTYGAGGST
RERTHNTVARIARETPLAAAAHLTCVAASTDEIDEIADAYWQAGVRHIVALRGDPPEQGG
RFEAHPDGYAGAADLVEGLMKRHPFEISVSAYPEVHPDARDPQSDLDNLKRKLDAGATRA
ITQFFFEADTYFRFMDKVRAAGIDAEIVPGIMPVGNFAAVQRMAAMCNTDVPAWMGRLFE
GLDDRPAARQLISATLAAELCRKLYEGGVRDFHFYTLNRAEHSYAICHLLGLRPRVTVEA
>U7L916|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. KPL1821|TrEMBL
MSPRLSASAPLDYESEEESHVPERLALSFEVIPPRHDADAAKIDRLLEVLESYHPDYIAV
TSSQRSGWLEGTAAFIEKISQNTSMRPLAHLACTAGSRDELIGWINRLVDAGVRGLLALR
GDLPEGGMPEHYLQHADELVRLIRELESHQAARFAAGRLAVSVACYPSGHAESKNEDEDF
DVLLNKQRLGADFAITQLFFDAEDFLRFAQRAELAGVKIPLIPGIMPMTSLRRLERMGQL
SGLTVPERVRTQLAAATTPEEEYEIGMELTAQLARTIVAGGADGLHIYTHNNPDITQDLL
SRIGVSNDEH
>A0A1W9T096|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_123|TrEMBL
MKLKEKIKDGKFAILAEIEPPKGSDTTNMVTNALRVKGVVDAFIVPEMSNAVMRMSALGG
ALILQGRGMETVMQICCRDRNRLALQADILAANACGVTNIMAVTGEDTGFGDHHQARDVY
DIKQIELLQTIQKLQAGRDMAGIELEGSPQFMVGSVANAGATGKDLDREMVEMDAKIMAG
CEFFIIPPVFDLEAVKPFLDRAQERHTRIIPTVLLLKSLGMARYITRNMDNVYIPNEIIK
RIQKAPDKARACVQLAAEMVASIKKAGFPGVNIVTIGWEKKIPEILGGMGV
>A0A650GDF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium sp|TrEMBL
MSADTTPLDRAGRVLRLRGGRRHQTLMAALDGASYEILPFKGTEDAVLAHVPRNVALSVT
TTEAKGLRPTVELASSLARHGYRTSPHIAARLVRDRHHLADIVAELDDAGVRGLFVVGGD
AAEPAGAFADALSLLEALEEMGHRFDDVGIGGYPEGHGSIARSVIDTAMEQKARHATYAV
TQLCFDPATTASWAHGLVARGVTLPVRVGIPGAVSRQKLVRISAGLGLGQSARFLRKQQN
LLWRFFLPGGYSPDRLVGRLAPEIGLPGTGIAGFHVFTFNELAKTEAWRQRLLADFESAR
RSR
>F2LY63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hippea maritima (strain ATCC 700847 / DSM 10411 / MH2)|TrEMBL
MKISEILNRKAMTISFEFFPPKKVENEQTLFNTINVLKDYSPDFVSITYGAGGSTKDKTV
EWTLRMKNEYSLNPMMHLTCVASTKESVDKVAEILELNGIDNILALRGDLPEGFEVKSMD
FKYAYQLVGYLKDKWNFSIGVAGYPEGHPESSSLDKDIEYLKMKVDAGGEFVITQLFFDN
GKFFNFLDRVEKFHIEIPVLAGVMPILSLSQMRRFVGMCGATIPSELISRLEGKTKEDMY
KIGVEYAINQCRELIDSKVRGLHFYTLNKYNATKDILEGLNI
>Q3EQ85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar israelensis ATCC 35646|TrEMBL
MLGLSALGMEEVLALTGDPARVGDFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPA
TRFSVGGAFNPHVRHLKAAVKRMERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIF
IGIMPLVSKRNADFLHFEVPGITLPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYF
NGIYLITPFLKYEITEHLVKYVREKQEVKEGIN
>A0A2T1E5N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenomitos frigidus ULC18|TrEMBL
MSDTVPCAPDTRPPTSTFRAAAQQGDFLITAEVMPPKGGNPAHMIEMARLLKGRVHSVNI
TDGSRAVLRMSSLAASALLLREGIEPIWQVACRDRNAIGLQADLMGAQALGIRNVLALTG
DPIKAGDHPQAKAVFELESVRLLKLIHKLNAGFDLNDKPLTDGATELFVGAAIDPQCGSW
SGLQSRFERKLAAGAQFFQSQLISDFDRLEKFMTQLAVGCNKPILAGIFLLKSAKNAQFI
NRCVPGVQIPDHLIDRLARTSDPLQEGVAIAAEQVQQARQLCQGVHMMAVKREDLIPQIL
DRAGIAPLKK
>K2LSP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor pacificus pht-3B|TrEMBL
MPQSHFSRRPDTAGKLRVSFEFFPPKTEAMEARLWETVTRLAPLAPDFVSVTYGAGGSTR
ERTARTVRRILEETTLTPAAHMTCVDASREDVDHVIGEFAALGVRRFVALRGDSSAGVGE
AYKPHPGGYSNGAELVGAMRRQGEFDISVAAYPEKHPESADFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHNFAQVANFASRCGAHVPGWLAERFD
GLENEPQIHALVASAVAAEQVIDLIDRGIDEFHFYTMNRADLALAVCHMIGIRPGSSEAK
AASAAA
>A0A1E7ICC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium C00003093|TrEMBL
MSEISIELVPRSKASLTRELQLVHERFPSVQRINIPDILRFRLRSWQGCAIAGQFFPKTI
PHLRAIDFDPNKPLQIKTELTEAEIEAVLVVTGDPPQDMARKCYRTSCLEMIRRLKRELP
QVKVYAGMDPYRSGIKEEIDYIRAKQDAGAEAIFTQPFFDLRLMEIYQGFLQDCTVYWGI
SPVLTENSRNYWENKNNAIFPPDFAPTLEWNRNFAKRALQFARDNGSNIYFMPIRTDIAA
YLDGIL
>A0A8D4TWX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DNDPTTRNLVAASVAMDMVKILSCEGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A2Z5JYA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Go-475|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSTDWDTDVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLERIGSLTNAAF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPAQA
>A0A1L3GF95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophotalea acetylenica|TrEMBL
MKRAACGFLERLEQGVIVGDGAMGTLLYQRGIPLSFCFECLNLRQPDVVRRIHRDYLAAG
AELVETNTFAANRLRLAAAGLEEQTRQINALGARLARQEAGRRFLVAGAVGPLGRAPGET
AELSREQRAALFREQMEGLAEGGVDLLLLETFASLEELELAVAEAGGTGLPVVAQMAFFE
GGKTREGVTAAEVARRLVGAGASVVGANCGSGPRDVLAVLRTMATQVNIPLSGFANSGFP
EYVDGRYIYLATPGYFAARGREMVEAGACLVGGCCGTTPEHIRALAAAVAGFKPSIRRIK
PQVAAVAPATVARDTPRQGFLSDWGKRPLITVELDPPRGMDCRKILEGARRLAVAGADAI
SLAENPLARIRMGNIALAKRIQDEIGIETIIHVTGRDRNLIGLHSELMGAHLLGLRNVLA
VTGDPVAVGGESGASNVFDLNSIGLLELVRALNNGHTLVGGELGEPTRFKAGAAFNPNVS
DMDAQLRRLGKKIAAGACFVQTQPIYSIPVLDAMLDGMADVDIPVLVGILPLVSERNAEF
LHNEVPGIRLPEEVRRRMHGASGEEGVRRGLAISRELVEAGRGRVDGFYLMPPFGKVDMA
LSLIEAIRV
>A0A847M2I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MNISLEIVPRDEPTIAENIAIASRFPEITLINIPDLLRFPIRSWEACPFIPATYQSIPHL
RAIDFNMDEPFPLTDYFRNHHIDTVLVVAGDPPQDMKHRVFPTHTTDFIKKLKRELPALT
IYAAFDPYRSNIRYELDYLKAKEDSGADGFMSQPFFDVRLLEIYAEYLEGRTVFWGVSPV
LSEKSRNYWEARNRAIFPRSFRPDLHWNISFGRQVLQFCKTHRFDLYLMPIRVDLDTYLQ
GLFS
>A0A0D6TDM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. 228|TrEMBL
MTTPNVSFEFFPPKTLEASFKLWETAKVLAPLAPDFVSVTYGAGGTTRKLTHEAVTTINR
QFGLQVAAHLTCVEATRAETMEIVQSYADAGITQIVALRGDAPKGADRFTPHDDGFANSV
ELIEAIAARGDMTIRCGAYPEPHPDSADGDADVTWLKRKIEAGATSAITQFFFEPETFFR
FRDKCVAAGIDAPIIPGLLPVQSWAGTKRFAATCNTTVPDWAEEAFQLAALDGPDAQRAL
ATDLSVDLCEKLIAGGVDQLHFYTLNRPELTRDVCAALGVRPKAGLEAVA
>A0A3N4YZN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TLI_185|TrEMBL
MTTFSFEFFPPKTAAGERTLWQAIRRVEALRPDFVSVTYGAGGSSRDRTIEVTRRIAAET
ILRPVAHLTAVGHSVAELRHIIGAYADAGIRDVLALRGDPPGAPKGPWVPHPDGFTHAYQ
LVELVRSLGNFTIGVAAFPELHPRSSDWDADIRHFVAKCRAGADYAITQMFFHVEDYLRL
RDRVAAAGCDIPIVPEIMPATDVRQIRRFAELSDAAFPVDLAHHLEAARDDPATGHRIGV
EYATAMAERLLAEGAPGLHYITLNRSTAALDIHRNVMSSRSIRVA
>A0A7X8FV84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MKIRDILDKRKLSVSFEVFPPRQDSGIEGVMRCTNELAELNPDFISVTYGAGGGTSANTV
RIASHLQTIGVTPIAHLTSYSSTKDEVHRVISELKEKNVYNILALRGDKPRDPDFVPPGD
YRYASDLVSDIKSLGDFCVGGACYPEGHPESGGREQDISNLKAKVDAGCSFLTTQMFFEN
SLLYSFLYRTQAKGITVPVLAGIMPVTSGKQVQRIRELSNAYLPTKFLSLVDRFGDNNDA
MKQAGIAYASEQIIDLVANGVRGIHIYAMNRPDIVRAIMANISSILEGARAL
>N9SYF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter genomosp. 16BJ|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKTVHQELQQLNPEFFSITYGAGGSTRERTLAAISDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A2H0AQT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG23_combo_of_CG06-09_8_20_14_all_51_20|TrEMBL
MKDESRLKQLLDGGHFAVTAECGPPKGADPGAVLRKAGLLKEKVDAVNVTDNQTAIVRMS
SIAACTVLLSAGLEPVLQMVVRDRNRIALQSDVLGASALGIRNILCLSGDHQSFGNQPSA
LGVFDLDSMQFIEAVRGMRDAGTIMGGEQLTSAPAVFIGAAANPFADPLEFRVVRLAKKI
SAGAEFIQTQCIYNMERFKKWISLAEDRGLLEKAYILGGVTPLKSAGMAKYMKNKVAGMD
IPDDVIKRMDAVPKERQRQEGIGICVETILALKEIKGVKGIHIMAIEWEDAVGEIVERAG
LLPRPKVD
>A0A3M4F449|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas marginalis pv. marginalis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SKAKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLHNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1R3T7H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteiniphilum saccharofermentans|TrEMBL
MRVSELINNTGKTAFSFELLPPLKGNSIQQVYNAIDRLKEFDPKYINITTHHSESIYKED
ENGTYRKVNVRRRPGSVAIAAAIQNKYGIRAVPHIISQGFSREETEYALIDLSFLGVTDL
LLLRGDTKKLDAEQRKMDCHQHATGLQEQVNNFNEGITFDGSSFTPPEEPFSYGMACYPE
KHEESPNMESEIYYTKMKVDNGAEYLVTQMFFDNSKYFDFVKRCREVGINVPIVPGIKPI
HLKNQLTALPRIFRSDIPEELAVALRKCKDDDEAKEVGVEWCITQCKELIRNQVPSIHFY
SLMATESVRRVAEEIY
>A0A525HN64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
MATPMFADLAGDAAVSFEFFPPKTEKMEETLWESVQTLSPLGPRFVSVTYGAGGTTRERT
HATVARIARETSIPAAAHLTCVAATKDEIDAVASEYWDAGVRHIVALRGDPPVAGTKFSS
PVGGYENAAALVAGLKKLHPFEISVAAYPECHPDSPDPGHDLDNLKRKMDAGATRAITQF
FHEADTFFRFRDAAAKAGIDAEIVPGIMPVMNFASVQRMSAMCGTAVPKWMGTLFEGLDD
RPAARQLVSATIAAELCRRLYAGGVRNFHFYTLNRAELSYAICHLLGIRPKPELQEKAA
>A0A7X0A486|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. FT3.2|TrEMBL
MKITEHIKNANGKTLFSFELIPPLKGQSIQGIYDAIDPLMEFKPPFIDVTSLREDFIYKQ
HDNGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLVDLQFLGIEN
VLVLRGDARRGDASFVPTPNGHNYATDLLKQVVNMNNGVYLHEHNDDSLKTDFCIGIAGY
PEKHFEAPNLKTDFKYLKQKVDMGASFIVTQMFFDNQKYFDFVNNCRANGINVPIIPGLK
PVTNSKQLIGLAKTFHIDMPEDLCDAVNGCKSEKDVRDIGVEWMINQCRELIAFGVPVLH
FYTMSNAGPTKRIAEAIF
>A0A625Y2J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCID
>A0A853VAF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LCM 4577|TrEMBL
MTALQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAQRLDHILHDEITETQVDMVK
TAH
>A0A625Y1F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
DYWNNGIRHIVALRGDLPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQA
DLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFA
DMTNVRIPSWMSLMFEGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSY
AICHTLGVRPGL
>A0A6I4NW76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium hydrocarbonoxydans|TrEMBL
MKVTEHIENAKGKTLFSFELIPPQKGKSIQELYDNIDPLMEFQPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKVGGNHFAIDLVKQINNLNCGKYLHEVMDVDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A6P3A2R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MNTIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVV
>A0A4Q2K280|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Senegalimassilia faecalis|TrEMBL
MNTITNIFTQARNAGTQPISFEIFPPKGELSMESARSMAEELAKLDPSFISVTYSAGGSG
NKQATAEIAAMIQDDFSVPTIAHLTCAGASEESIAAAVSDMKGRGIRNVLALRGDLPEGY
KPGDFKLAKDLIPRLTEAGFCVGAAAYPEGHIDCDSMRLNVEHLKQKEDAGAEFFVSQLF
FDNEYFYRFREQAEAAGITKPITAGIMPFMSKAQISRMVFMCGASLPSPIIKLLARYEND
PASLRQAGIEYACRQLTDLQEHGVDGLHVYTMNNPEIARAAMCALKVALVR
>A0A176VGK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marchantia polymorpha subsp. ruderalis|TrEMBL
MKVIDKIKEGEANGRVVYSFEFFPPKTEEGVENLFERMDRMVAHNPSFCDITWGAGGSTS
ELTLDIANKMQNMICVDTMMHLTCTNMPVEKLNSALDTVKANGIQNILALRGDPPHGQDT
FVQVEGGFSCALDLVKHIKEKYGDYFGITVAGYPEAHPEVILEESGATEEAYRKDLEYLK
KKIDAGGELIVSQLFYDVDIFLKFLDDCRQIGISCPVVPGIMPIVSYNGFKRMTGFCKTK
IPAELTAALEPIKDNEEAVRAFGVHYATEMCKKILAHGVTALHMYTMNMETSALRILQNL
GLIDITRVNRSLPWRPPTNQKRNGEEVRPIFWANRPKSYITRTTEWNEYPQGRWGDSRSP
AYGTLNDYQFLRRRTRNKKLAKEWATPLTSVADVHEKFVKYCKGEINTIPWSEVDGLQPE
TKTINEDLVDVNNQGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSAEKLQ
ALVEGIKGTPLTFIAVNAKGETKSNIGPGDVNAVTWGVFPAKEVIQPTVVDPVSFMVWKD
EAFQAWTDEWASLYPENDSSRKILSEIASSYYLVSVVDNDYINSSLFKVLRA
>A0A5Y7AJC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Infantis str. CFSAN000522|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2M9P9D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amaricoccus sp. HAR-UPW-R2A-40|TrEMBL
YRHVNPEWSFFAAVSRYLDALPDDAYDLIIFDSLAQTGEFEISVAAYPEKHPEASSLSAD
IDNLKRKIDAGATSAITQFFFDNADFLRFRDACAAAGIAAPIQPGLLPIEKFPKMVNFAA
RCQARVPDWLHTAFGRALDEEEIGRLSIAVAVDQWRGLIDEGVEHLHVYTLNNPDLSFED
RGGGPRRRGASLPHRG
>A0A0F4L065|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium asteroides|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLMPDFISVTYGTGRRSDRTATARIAKTIH
TEYGIPAVAHLTAQYADREVIDQALDMFDDAGVAAVLALRGDSVEGREPAGVFDHASDLA
AYIRSRRPNLSIYGACYPETHPEAASPEEDIENLRIKVDSGVDHLVSQLFYDNADFLDFL
DRARAAGIQVPIEAGIMPITNEGQVRHMSEVCQARIPAAVESILERWGDDRASLREAGII
YASQQIADLVAHGVDGIHLYSMNHSGVTRRIWHNVRHLFRQVGTKDEPVSSQK
>A0A2H9YTB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pseudolwoffii|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAADLVR
FIREYSGDHFKIEVAAYPEMHPQAESFDQDIQHFVEKVQAGANAALTQFFFNPDAYFYFV
ERIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>D1YAD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium acnes J139|TrEMBL
MAPDFISMTYGANGSRCDRTLRCTQHMVSTGLRTVGHLTCVANR
>X5XUU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNJC405B00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDEIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A1G4VEC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcaceae bacterium P7|TrEMBL
MKITSLFENKTRTVFSFEVFPPKKSSPIETVFRKLDEICALKPDFISVTYGAGGSENRNR
TCEIASRIKNDLGVESVAHLTCVNSSKAEIDAILEEFRQHNIENILALRGDYVQGVEPKR
DFLYASELVAYIREKGGFDLAGACYPEGHVEAEDEIADVLNLRKKVDAGATHLISQLFFD
NSAYYRFLERARIAGINVPIEAGIMPVTNKSQIERMVSLCGASLPAKFSKIMQRYESRPE
ALRDAGIAYAVEQIVDLIANGVDGIHLYTMNNPYIARKITEAVSSLL
>A0A3E1L473|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAAKLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDADSDLKYFKAKVDAGADAAITQYFYNADAYFHFRDA
AQRLGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDADAVRAFGAEVV
AALCERLIAGGVPALHFYTLNLAKPTTQVLQLLGR
>A0A7X7SWT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MRISDLFKNSKQLISFEIFPPKLDTPIETIYKKLGDFVSMKPDFISVTYGAGGSKKGRTI
EISTKIKNEYKTECLAHFTCVGHSISEIDNMLAQMEKEGLDNILALRGDPPQDNPDFDFS
KNVFTHASDLIQHIRKQHDFCIAAAAYPEGHVDSPRIKDDMHYLKIKVDQGVDFLITQLF
FDNRVFYDFLDKCEAYNISCPVLPGIMPVFKADQIKRIALMCGASMPAKLVLLLDKYKNT
PDMEKAGIEYASDQIRDLLDSGVKGVHINTMNRVDATYSILRNIGRL
>A0A8J3TZV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planotetraspora phitsanulokensis|TrEMBL
MALGLPSRLPERVPTVRELLAAGERSFSFEFLPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLIGRFADAGVRNILAVR
GDPRGADPLSEWIKHPEGVQYAEDLVRLIRQAGDFCVGVAAFPYKHPRSATIESDTEYFV
QKCRAGADYAITQMFFRAEDYLRLRDRVAASGCDTPIIPGIMPVTQMSTIARSEQLSGAP
FPPEVAARFEAVADDPVAVRRLGIEHAAEMCRTLLDEGAPGIHFITFNRSSATREVFEAL
APAGSAVHR
>A0A6N8C2C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MYEISQRKDFSISAAAYPEGHVECADIGKNIEYLKEKVEKGADFLITQLFFDNDNFYNFR
EELYKNNINIPIVTGIIPVLDKKQIERIATLSGAVIPQKIKRIMDKYEHSPDALKEAGIA
CTSEQIVDLISNDVQGIHLYTMNKHNVAKEIMENIQELRKIVNS
>A0A6J0KC44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raphanus sativus|TrEMBL
MKVVDKIKSATEQGQTAFSFEFFPPKTDDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNAICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRKIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAFGIHFATEMCKKILAHGITTLHIYTLNVDKSAIGILMNL
GLIDESKITRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYGTLSDYQFMRPRARDKKLQQEWAVPLKGIEDVQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEKLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TLVEKSKAFPSITFMAVNKAENWVSNIGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDEPSRKLLEEVKNSYYLVSLVDNDYISGDIFSVFA
>A0A7X9BTL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKIIDKFSETNPMISCEIFPPKEGYPVNTIYDTIDELNSLNFDFMSVTYGAGGSTKDKTV
EISSYIQKQHNLTSLAHVTCITSSREEIEQILESFKRNNIQNVMALRGDYPKDTTADVFP
KGGFKNSVELIDFFKRNSDLCIGGACYPEKHPDAKDLDADIDFLKRKMDAGADFFVTQMF
FDNEAFYDFYDKTAQKGIDVPIVAGIMPILNKRQVNTITKLTGNSIPKKFERLLAKYEDN
PEALREAGMSYAISQIIDLLSWGVDGIHIYTMNKSSTVKTILGSISAIRSVLTHESKSLK
K
>A0A317J7Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriia bacterium|TrEMBL
MPVGNSIREALTGGRFCYIVELVASQLTREAKLLDVAVRLSQVPGVVGAGITSYAGGAMG
HDPVRVGTAARARGLTPNIHITCVNKDRHTIRRELEDLIALGIENVFAITGDYPKGLDAA
NIASPYDLDSVQLVEFINELREAGHPFYISAAVSPFKYTEADCAYQYLKLEKKIAAGADW
AITQLGYDSRKFRELKRYMDERGLHVPLFGNVYVLPAKAAQRMSKGEPPGCWVAPELVER
IQEETQQSTDKGLAARLERAAKMVAIVRGLGYAGAYLGGDHQADRIRWIIKRSEELAPRW
EELAEEISYAPKDAFYMYEGPRPPKKKRGFWLRLADLGEPANTPRFLRGLLTAAYRWIDR
RPALARAFERAELSFKEPVFGCKACGNCVLGLTEYVCPMTCPKNLRNGPCGGTLNGQCEV
FPDRACVWVNVYERAKAADRVEDLKVFIPARNRALEGTSSYINYFLNRDSRPEHPVRLVQ
IGPAPAAKPEPDATLVPK
>A0A7X9GLX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKINELFKKNRPIISFEIFPPKPDIPLDTLFESIEGFKKLSPDYISVTYGAGGSQRGRTV
EIASRIKNQYDIETMSHLTCVGHSTEEIDGMLVKMKEQNISNILALRGDPPLDQPEFDFS
KGAFQYANELIEYINSKHDFCIGAAAYLEGHVDSKRLSEDRRHLKNKVDAGVDFLITQLF
FDVRLYFDFLDRCEQININCPVIPGIMPIFSARIKNMTARSGCSIPAKLVLMIDKYENNP
DDLKKAGEEYAGLMIRELLDGGAPGVHLYTMNKLQSTIEIMKIAGLLNN
>A0A7X8L7L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKISELYKNKRKTLAFEIFPPKPETPLDTLFNSIDGFKKLSPDYISVTYGAGGSQRGRTV
EIASKLKNHYGIESMCHLTCAGHSVEEIDELLAKMKEENISNILALRGDPPMDQPDFSFE
SGAFQYANELISHIKKNDDFCIAAAAYLEGHVDSKRLSEDRYYLKQKVDAGVDLLVTQLF
FDIRLYFDFLDRCAQLNINCPVIPGIMPIFNARIKTMTARSGCSIPANLVLMIDKYQDNP
EDLKKAGEEYAGHMIRELLDGGAPGIHLYTMNKLESTIEILKQAGLR
>A0A7X4ZCL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKIRDILAKGEPTLSFEVFPPKTEDKYESVEHAALEIGKLKPAFMSVTYGAGGGTSRYTV
DIASTLQNQGVTPLAHLTCVSSTREKVMSVLEELKSRKIENILALRGDIPADGQVERDYH
YASELIGEIRRSGDFCIGAACYPEGHVESVNKACDIHYLKEKVEAGCDFVTTQMFFDNNV
LYNYLYRIREAGVTVPVIAGIMPVTSKVQIKRICSMSGTYLPARFKAIVDRFGDNPAAMK
QAGIAYATEQIIDLIANGVNGIHVYSMNKPDVAAKIRDSLSEILK
>A0A243SIS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. FPG59|TrEMBL
MKVTQHIEKAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNGLLDKKLTRMRPGTLGICASITHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGINN
VMALRGDAMKDEQSFVPKAGGNRFAIDLVQQIKLLNEGKYLHEVMHVDNKADFCIGVAGY
PEKHLESPSLLSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PLAVQRHLQILPQIFRIDLPEDLIDAVDKCKTNADVKQVGIEWAIQQSRELKAAGVPVLH
YYSMGKSENIRQIASQLF
>A0A2Z6U447|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciecola sp. (strain KUL10)|TrEMBL
MVSYAQGIDALNQTISELRDIEVSFEFFPASTPEMETTLWKSVERLAPLKPKYMSVTYGA
NSGERDRTHAVVKRINTETGIATAPHLTCVDATPDELRSIAKEYWDSGIKRIVALRGDLP
QGVEKTDMYASDLVTLLKDVADFDISVAAYPEKHPEAPNDQFDLLNLKRKAEAGANEAIT
QFFFDSSVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPNWLHKMYDGL
DKNDQTTRNLLGASIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGLRT
>A0A1I2WAW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolymorpha cephalotaxi|TrEMBL
MASGPASSAPRPSRTVRELLAGGDRSYSFEFFPPKTDQGELQLWRAIRELEPLSPTFVSV
TYGAGGSTRDRTVRIIARIASDTTLTPVAHLTCVGHSRAELRSVIGSYADAGVRNILALR
GDPEGGPNQPWIRHPEGLDHADELVTLVRELGDFSVGVAAFPEGHPEAVSLDADAEYLAA
KAAAGADFAVTQFFFDADDYFALRDRARKLSCEIPIIPGIMPVTNVRQIQRFAALSGAAF
PPDLAERLLAVEDDPAAVRAIGVEAATELCRKLLDGGAPGLHFYTLNRSTATREIYANVV
GPVARAS
>A0A1Y2L0D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira mesophila|TrEMBL
MTVQRDNTQTPPASGRDLRVSFEFFPPKTEKMEETMWRSIHRLAPLAPSFVSVTYGAGGS
TRDRTHASVTRIQRETGIPAAAHLTCVGHTRDEIERIARTYWDEGIRAIVALRGDLPDAG
DRYVPTPGGYDYAVDLVEGLKKIADFDISVSAYPETHPDAPNADFEIDYLKRKLDAGANR
AITQFFFDNDVFLRFRDKCDKAGITAPIVPGILPVTNFSALLKFAGMCGAKVPNRMHRSF
DGLDEDPDTRRMVAFHESISQVEGLMAEGVTDFHFYTLNRAELTYAICHALGIRATPVAA
TA
>A0A495RES0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orbus hercynius|TrEMBL
MKINQKFKDKTILSFEVFPPRKTSPLESIYGTLRELGNLKPDFISVTYGAGGSLNGETTI
NIAHAVKHTYGIESVAHLPCIHFSKDEIKSILTELNHAGVVNVLALRGDITPEWQPKKDF
NYASELVTFIKEQGDFNVIGACYPEGHTEATTVKQDLINLKEKVDAGTNQLISQLFFDND
YFYVFREKAASMGIHVPIEAGIMPVVNKKQIERMVSICGVNLPKKFKQMMEKYEHHPEAF
RDAGIAYAIDQIVDLVSQDVDGVHLYTMNNSLIARRINESVASLFSVPKQIQ
>A0A1Q5KUE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB01883|TrEMBL
MTGKDVSRLEEASDGIPPGTRINITFLAGEDLATRLTAARAVRRLGFVPVPHISARRLPS
RAALQEFLSGLAADGTAENVFLVGGDPARPEGPYADALALLRTGLLQEHGVRHVGISGYP
EGHPAIPDPTLWSALTDKAAAIGAHRFGGDVITQFGFDPAPVLGWLEAVRARGVHLPVRI
GVPGPAGVRRLLGYATRFGVATSASVARKYGFSLTNLMGTTGPDRFLHALAERYDPARHG
RVKVHFYTFGGLRTTAEWVARFRHEDHTPTGRP
>A0A1H1WU10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium siliguriense|TrEMBL
MSSTFVTSRLSASAPDSAPDRLPVDRRRLRRALSFEVIPPRSAAQAARMPRLLRFLDTLG
PDYLAVTSSATSNWLQGTADFIAEVTATTTLRPLAHLACTAGTEAELLTWIDHLLGVGVR
GFLAIRGDIPEGQSTVPAGHLPHADALVTLLRRIENDNVACLAAGRLGIGVAAYPSGHPE
STGPEQDLDVLAAKQRNGADFAITQLFFDPASYSRLRRRAEHAGIVIPIIPGILPITDPR
RLHTMARLSGLPVPDGLLARFNGISDPASARRIGLDITAEHTAAILEHDADGLHFYTFND
QNTTEDLLTALEQKGISMSSFSPQPPPRRWPPSTVHTKPTTKENHA
>A0A0D6DWR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus piscium MKFS47|TrEMBL
MKITDIYKTKNKKNKSVISLEIFPPKTDAGVETIYHTVAELTNKPDFISVTYGAMGSFNQ
GNKTLRIAEKIKKDYNIETMHHLTSINNNPEQIAAILSDIKAKNVNNILALSGDMPVGAA
CSDFPDAYHFAYELINDIKKNGDFDIAAAIYPEGHVNSALEVENIEHVKRKYDAGANLFV
SQLFFDNEKFLRLNDYIKNSGIEAPIAAGIMPVLQKSQVERMIFFGASLPTRLIKIINKY
KGSPDDLQKAGMEYACKQIDDLLARGVDGVHIYTMNKPFVANTMMTKYL
>A0A1Q7CAZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_2_20CM_2_66_6|TrEMBL
MRRFLSHPRYEVLPTEESGDLVMRNLPTEVTITVTSSPRRGIEATLALAERLAGGGYAVV
PHLAARLVRDESHLKEILARLDAIGGRVFVVAGDSQQAAGAFPDSVSLLEAIASHAPAMK
EIGVTGYPERHGFIDDDLTIQAMWDKRRQATYIVSNLCFDVRVVKKWIARVRKRGVPLPI
FIGMAGVADPAKLLRVSTRIGIADSARFLRGHTNWLMRLIQPGGYAPDRFATGLMPELAR
PDMKVAGIHVFTFNEIEPTEQWRQQMLARLS
>A0A399IC01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
MPSHFAHKLAADEFVITAEIAPPKGCDPAGLMRTAISLAPFVDAINITDNQGANMRMTPL
VAAGMLVREGIEPIMQLTCRDRNRLALQSDLLGAAAMGVKNVLALTGDDIGCGDHRQGRA
VFDLDSVLLLQTIGALNSGFDLNGAPLAGATDFLAGAAAAPEVEPFDATRPKLVKKAAAG
ARFFQTQAVFNPERLAYFHDAVQPLGVKVIAGILVLKSARMAEFINLNIPGLKVPLPVIE
RLATAADPAAEGVRIAIELALQCRSICSGIHVMAMGRYEVVPQLIAAIRS
>C9PRE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella dagmatis ATCC 43325|TrEMBL
MSYAKEIDTLNQHIADLNGKINVSFEFFPPKNEKMENILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLDAAPHLTGIDATPEELVEIAKDYWNSGIRRIVALRGDEP
KGYAKKPFYASDLVSLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLVKMAAITNVKIPAWLAKNYEGL
DDDQTTRNLVAASVAMDMVRVLSREGVNDFHFYTLNRSELTYAICHTLGVRPA
>A0A4R4G6P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuricurvum sp. IAE1|TrEMBL
MFESFIRKLRNETYITLETTPSRSARFAPTVDKIESLGLQHLVDGFSTTDNPLAKLKYNA
LFAAQMLQNRFGLPVLATMSMRDRNRIALQSDLLGANEADVRAILALTGDSAHYSDQPHA
KGVFEANSKLLLDIIATLNAGTDMAGQKLLSPVQEIYPFAVTDAYAKSAATLQKKMSKKV
SHGAIGVISQPVYDLENARKLLEMMENANAEHSAASVLVLGYFPITKLRTARFLDENVPG
IFVPQGWVEALEAAAARSPEEEYRVGFDLSKNLFEELKALHPKIHIMTANQFELAKAILS
>A0A368AL56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. AFG_SD02_1510_Pfu_092|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSTERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFANPVPALPHFSGKDRERQHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMRRQATPRPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIDHWQAQVHSLEQWAPA
WQASWQLPGLPAVSFHPPQAAWRQGESRVDASLKEKARYHLMHSLHSLLFSRRNGLSKAF
GWAVRQPVWATRLGAQVLHKVERAVKHPLTGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCVEVETRHRSSWPQWFAPPTS
RRLSPQPAPRSQPES
>A0A7S6VXG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter piscicola|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTIADFN
GKGTPVAPHLSCIGDDKARIAELLDIYRAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQRFCDKVRAGANAALTQFFFNPDAYFYFV
DRIQKEGVDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLIVGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A2H5T4A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus irregularis (strain DAOM 181602 / DAOM 197198 / MUCL 43194)|TrEMBL
MKITDKINNNLETSQPFYSFEYFPPKTDEGLNNLYDRLKRMSHLDPLFASFTWGAGGSTI
DRTTEMCATAQSLYGLESCMHLTCTNVVRGTIEKAMKEAKSAGIQNILALRGDPPRGQEY
WTSCDSDFTHAIDLVRFIRKEYGDYFCIGVAGYPEGNPDSENKEQDLKFLKEKVDAGADF
IITQLFYDVNTFVEWRDECRKNGINVPIIPGIMPIQGYNSFRRITNLCKIHIPAEILNVL
EPIKHDDQAVKDYGVTLAVSMISKLRNEHNTRGFHLCTMNLEKSVRLILEILGFVQTEEE
RNLRRLSRRRSSAGFGPNDIIRQEPDGSLPTAKPVIWKERSVDYLGRPEDWDNFPNGRWG
DARSPAFGELDGYGVSLRIPPEQALGYWQRPMTLDDLKQVFKSYILGEIPALPWYEEPLY
AETEAIRSKLVHLNELGFLTVSSQPAVNGARSDDPIYGWGPRGGYVYQKAFVEFFVSPEN
FEELVEKIKGNPWVTYCASNRNGDFRSNTKDDSPSAVTWGVFPGKEIVQPTIIAKVSFNT
WKDEAYALWTEWEHLYPKDSPSQRLLKDIGDNWWLVNLVYHNYVNSEEIWEIFFKS
>A0A4V1A2Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ureibacillus thermophilus|TrEMBL
MGLLEALKNSVLVADGAMGTLLYSYGLESCHEEMNIERPEIIEKIHSEYIQAGADVIQTN
TYGANKIKLTRYGLESKVVEINKGAIEVARRAAAGKDVFILGSIGGIRGVRKVDYTLDEI
LEAVREQAEVLIAGRLDGLLLETYYDFEELTETLKMVRAMTDMPIIAQVSMQEPGVLLNG
LKLNEALKQLEQLGANIVGVNCRLGPYHTIQAFEEVEIPEKAYLSAYPNASLLDIEDGRV
VYESEVDYFARAAVELCNEGVRLIGGCCGTTPKHIEAVKKKLAHFRPIEKKVAKPVREAI
IQEAEPHSFEPLHEKAKRERSVIVELDTPKHLEIEQFVEGAKALYEAGADLIMMADNSLA
SPRVSNLAMGAILKLQYGIRTMPHITCRDRNLIGLQSHLMGLNALGLHDVLAVTGDPTKV
GDFPGATSVYDVSSMELISLIKQLNEGISFSGKSLKKKANFSVAAAFNPNVRVIDRAVSR
LEKKIEHGADYFISQPIYSKEKIVEVYEVTKHLETPIYIGIMPLTSFKNAEFLHHEVPGI
KLSDDVLERMKQVSGNKEEETKVGLEIAKELLDTATQYFNGIYLITPFMRYELTIQLLQY
IQQLDEQNKGVKANG
>A0A3M3Y7T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. primulae|TrEMBL
MSVLKKALLDGVFTCVVEYVPKPSSERFTAFEALMEQSRLHEWPLVPAVADRVGGKFDIA
PVDACAALKGPTPALIHFSGKDRERSDLLSELDRMDRLGVNQLLLISGDRLPGHQPGQHP
VRYLESVPALQIARAARPDWLLGAALNPFKYREEEGCAQYLKAHKKLAAGADFLTLQLGF
DAKKHIEAVAWMTSQKTPKPLLACVMGLTEKRASLLKSVPGIVVSPSMLGVLAAEAAVSK
EHARSRCTDRLALQIVGLRLMGYAGIHLSGIHTVQELEALEQRISVWVKNIGSLEHWSAA
WADSWQPPGQLAVTFNPPGASWYLGESSVKATPKETLRYHVLAGFHSSLFSHTTLLGGAL
GWAVRRPVWSSARGASLLRQLERSLKRPLVGCDTCGQCRLEDTLYICPETCPKGLSNGPC
GGTYLNRCEFGDRECIHSVKYRTAKSVRRIQVLTDRLIPCVEQGSRHSSSWPRWFEADAS
QTRGTSD
>A0A3S0KT12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella canadensis|TrEMBL
MGFHHAQHATSLNQSLAELNGDINVSFEFFPPATPEMEKILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETDLVAAPHLTLVDASDEELKELAKHYWNSGIRDIVALRGD
LPEGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDALNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFKQLKRFAGMTNVSIPGWLHKQFE
GLDDDPTTRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A495V1M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiocapsa rosea|TrEMBL
MPLQSQQTPTYSVELFPPKTPEGMEKLKLEIAQLDSVSPGYFSVTYGAGGSTRDRTFETV
DWLRGHNIETAPHIACVGSARAEIREIVGRYREQGIRRLVALRGDLPSGMGGGTGGDFRY
ANELVSFIREEFGDAFKIEVAAYPEYHPQSGSPERDLANFKRKVQAGADAAITQYFYNPD
AYFAFIESCERVGVSLPIIPGIMPITNFTQLARFSDACGAEIPRWVRRRLEGYGDDVESL
RAFGHEVVLNLCRRLIDGGAPGLHFYTMNQSGPTLRLWKDLALPLPV
>A0A3E2CGR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGV
>A0A2C5XC28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps australis|TrEMBL
MHIGSMVAEAGKGHQPSFSFEYFPPKTAQGVQNLYDRIDRMYNLGPKFIDITWGAGGRIA
ELTCEMVTQAQSVYGLETCMHLTCTDMGLERVNDALRKAYKAGCTNILALRGDPPRDQEK
WTATDKRFQYASDLVKHIRDTYGNHFDIGVAGYPEGCDDNKDENDLLDHLKQKVDAGASF
IVTQMFYDADNFLRWVTKARQRGIAVPIIPGIMPIATYASFLRRANHMQCKIPQAWMDAL
EPFKNDDVAVRDIGKTLVADMCRKLLANGICHLHFYTMNLAQATRMLLEELSWAPCAERP
LRHALPWKKSKGLGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRSKWGEPRSIRDIANTFVRYLEQDIDSLPWSESPLTGETDSIKPHLVA
LNKRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPREILNEMLHRIESRP
SLTYYAVTRTGQLKSNVASDGPNAVTWGVFPGKEIVQPTIVEGVSFLAWRDEAFRLGKDW
AHCYDSNTPSRALIDYIMDEWYLVNVVNNDFRENFAIFELFKDLEVKDLGFCQGESRQ
>A0A549YFB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentibacillus cibarius|TrEMBL
MTMMDQQTSATLFNQTGGPRFELIPTNGIVERATAALPSQATLTITCSPTNGINATVDKA
IALAPHFARVIPHIAARMIRSDDHLNVVLDRLAAHDVNDVFIVGGDQEKPLGPYHCGLDL
LQSLATHDNRALHIGIPAYPEGHPHIDTDTLQQDLKAKAPLAHYMVTQMCFDPEQVLAWL
QQQRASGVQLPCYLGIPGPVKLNKLLRIAPRIGVTDSLRFLRKNLKLSRKLMRGYDPSDL
VNAYTPYLNESDYGIAGFHMYTFNELETLKTVEEGGD
>C6HTS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospirillum ferrodiazotrophum|TrEMBL
MTFRQALADRSTFIITAECSPPKGTETSELLRKLLPLKGRIHGMNITDNQTAVMRMSPFA
MGLHLKTIGLDPIVQITLRDRNRLAIQSDLLGMSSLGIGQVLCLSGDPATIGDHPETKPV
FDLSSPELIRAVTLLNGGTDLSGADLTGPTDILPGAATSPEGDLSVEKKRFEEKFDAGAR
FFQTQVVFDADRMDRFMDFARPFGVPVICGIILLKSPAMARYLNEKVPGIRVPEPLIARL
ESVPREERLLEGVRIAAETIRTMAPLVNGVHIMTVGAEEQIPAILDLALG
>A0A672HBE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salarias fasciatus|TrEMBL
CCGREKKRLSLNPSDSSNSTSGGESSKESSRCSTPVLDADRSDRLRDKMRRRIESGDCWF
SLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYC
GLESVLHLTCCNQTREVITGHLAKAKHLGLKNIMALRGDPMGTDWEEEEEGFNYAVDLVK
HIRAEFDSYFDICVAGYPTGHPEAESYEEDLLHLKEKVEAGADFVISQLFFRADTFLKFL
DDCRRIGISCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITEVIEPIKDNDAAIRNYGIH
QAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVE
DVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLQM
WGEELMNEESVFEVFTSYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELDKVNRRGVL
TINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVSALLKVLKKYEPRVNYHI
VNVHGLNLTNAPELQPNAVTWGIFPGREIVQPTVVDPVSFVSWKDEAFALWIEQWAKLYE
DESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELINESLEQLRDSGDRLRTP
LLIQRTLSASCKLITCLMCLFLLFSKH
>A0A8H5IR48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium napiforme|TrEMBL
MHIKDMLSDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIGESRGSKTGSEIMLTMVVNNDFHDNKTIFELLKG
LEVKDLTTPATPLTESVGNGAVDTEPIANGTAATAVAN
>A0A673U5S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Suricata suricatta|TrEMBL
MTVEVPLPKRPGRGHIGDGASGLQLGCFPPSRPASLCNLTPAPRPAPLRRRSPGGHAAAA
GASSLSHPPKGGRNSVMVNEPRGDGGPTPRLEGSSSGSESSKDSSRCSTPGLDPECHDRL
REKMRRRMESGDKWFSLEFFPPRTAQGAANLISRFDRMGAGGPLFIDVTWHPAGDPGSDK
ETSSMVIASTAVNYCGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQW
EEEDGGFSYAADLVRHIRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFI
ITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIE
PIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRR
PLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYL
FYLTSKSPREELLKMWGEELTSEESVFEVFACYLSGEPNQNGYKVTCLPWNDEPLAAETS
LMKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLV
NLVDNEFPLDNCLWQVVEDTFELLNRPGTEQETETL
>C2WSS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus Rock4-2|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FILLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A852K785|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spizella passerina|TrEMBL
DGFNYAVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVYAGADFIITQL
FFRPETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKD
NDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPR
>A0A7R9R5S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MRVKDILNATKISFSFEFFPPKTDTGWKQLFDTISELMLLKPSYVNVTYGAGGSTRDRTY
NLVTQIQRETGLTVVSHLSCIGSTKEEIRSILEKYNQSGVENILALRGDPPKGEKLSSLK
GDFKYAADLVAFIKKHFPHMSIGVGGYPEGHPETPNRLKEIEYLKAKVDAGADYIVTQLF
FDNRDFYDFCERCELVGIHVPIIAGILPITSYQGMIRMAELAAGSRLPAPLLKSVMRAES
DEYVEKIGIHWATEQVRDLVDHNVRGIHFYTLNNSRPIFKIYEYLGVRDSIQLSAQPGHV
IRRDTKVE
>A0A8F6GPF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum sp. AHE15PA|TrEMBL
MKVTEHIKKANGKTLFSFEIIPPKKGNNIQDLYNNIDPLMEFNPPFIDVTTSREQHLYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIEN
VMALRGDAMSHQRYFEASKNGHQYAIELVNQIENLNKGKYLHEVIEANHKADFCIGVAGY
PEKHLESPSLQTDLKRLREKVDAGADYVVTQMFFNNQKYFEFVNAAREIGITVPIIPGIK
PISVKRHLQLLPQVFKIDLPEILINSLDNCKSNKEVRQVGVEWCIEQSKELLEAGVPLLH
YYSMGKSDNIKAIAKALF
>A0A2M7EU33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium CG17_big_fil_post_rev_8_21_14_2_50_65_11|TrEMBL
MPTPRVSFEFFPPQSLQASFRLWDTLGTLAPLAPQFVSVTYGAGGTTRDLTHDAVKTIHT
NYGVPVAAHLTCVNATREETLAIADSYAEAGVNRIVALRGDPPKGSDGFRAHPDGFASSV
DLVEALARRGTFDIAVGAYPDPHPEAENLQACVEYLKRKVDAGATTAITQFFFESDTFFR
FRDACADTGIAARIIPGILPVNNWTRVRRFAANCGTVIPQWVDDAYDTAIRDGREALLST
ALTSELCTELLEGGVEDLHFYTLNTPDLTRDVCAALGVTPQVALAEVA
>A0A3S0B0K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseriaceae bacterium|TrEMBL
MHITKHLAEAKKTIFSYEIVPPLRGTTSIQQIFDIVDKLLPFDPKWINVTTHASSLLYVE
NSDGTISKKIHKKRPGTIGICGVIQNKYKIDAVAHMICQGFSQQETEDALIELNYMGVDN
ILALKGDNLNYNRHIADYESTNTHAVNLVKQVDNLKHGKFLGDTEYPAIDFCVGVAGYPE
KHFEAANMELNLDYLKQKIAAGAEYIVTQMFFDNQKFFSFVKICRDAGITVPIIPGIKVL
KTVGQLTGLPKLFHIDIPNQLTQDVLANPENIKEIGIKWAKQQVRELIEFGVPCVHFFLM
NDVDSVVEIVREIEV
>A0A1A6C0P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidihalobacter prosperus|TrEMBL
MPSQADYPKIYSCEFFPPKTDEAGERLRAVRQTLAELGPRFFSVTYGAGGSTQARTLGTV
LEIQRDSGIDAAPHLSCVGSTREHIRETLDTYRKHAIRHLVALRGDLPSGMHDIGEFRYA
NELVAFIREETGDHFFIEVAAYPEIHPQARSASDDLLHFKRKVEAGADSAITQYFYNADA
YFRFVDECADMGLDIPVVPGIMPITNHAQLARFSDACGAEIPRWIRKRLEAYGDDRESIR
AFGLDVVTSLCERLLAGGAPGLHFYTMNQSEPTLSLWQRLGLPTPGA
>A0A7W7QI62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium saharense|TrEMBL
MTTPPFQVICEIEPPTRPDLMRVRHQIGTLSKVADTFLVPDNHIGRATVSSVAVAHEVEA
MGGRSIACLNSRDRNLLGFRRDMLTAAAYGVDRFLFVYGDKPATGNRTGDLNVRSMIEEA
HALPHDPAFAGVRPFQVGTASGLRPLPAWKRAADFIFAQVSFSLDALLEWREANPVEVPV
YAGVMVLASENHARRLAAAIPDIDIPEDLIRQVAADRQAGVEAACEQVLKIRDSGAFDGV
HLIPVSRYRQVAARLEDLL
>A0A7W7ZKQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulicella mallensis|TrEMBL
MAVGIDRLFAGGTILCDGAMGTMLYSCGVFINRCYDELNLSQPEMVRSVHQQYLQAGAEV
IETNTFGANSFRLERFALREKVREFNLAGAAIARQSVDAIREKQGTEAFVAGAVGPLGVR
LEPLGKLSLEEAREAFAEQISALAEGGVDLIIIETMMSIDEAEQAVLAARQVAPHLKVAV
MVTVDEDGNCLDGTSPEIAAERLTAVGADAIGCNCSSGPATVLTVIERMREATALPLLAM
PNAGMPRNVEGRNIYLTSPEYMASFVRKAVRAGASWVGGCCGTTPAHIRAMRSALRAMGA
QESGEKSTEHTPHVVHASESEHRVEPRPLGERSRIGRMIADGEFVTMVEIVPPKGFDCSK
ELAGALLMKKRGVHVINVPDSPRASARMGAQSLCVQIQQQVGIETILHYTCRDRNVLSMQ
SDLLGASSIGLKNILCLTGDPPKMGNYPDATAVFDVDAIGLVNIVHGLNQGLDIGRNPIG
GSAGFTISVAANPGVPDIEHEVRRFAYKVEAGAEFCITQPVFDLRLLEDFLRRIEGFRIP
VIAGIWPLTSLRNAEFMKNDLRVAMPDEIFVRMAAAGGKEEALAEGLKIAQEMLASVRGS
VQGVQVSAPFGKYTAAAEVLGLTEEIA
>A0A6H9WYP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoclavibacter sp. CFCC 13611|TrEMBL
MFSYRPLCLLRNSVVELPRLVGAATDCTECRRTYSTECRRTDCTEYSRTDRPECSRHGLH
GMYRDRSKMPPFCQSVAARCDRGSSRECRTSAGPRGCRPESAEPVLSPVGASSRVQNLFD
VGESAEDVRINRFWQRLLCSRCPNRTDRSKYRFCSRAAQVLCPNRTETTSPTTAPKPGPR
NLRTSSAPRCNVTSHVWRRRSDAEYDGATMTASAQPAADRRPQVARSNDAAVSTEASAEE
PVAERRFSASRFGLSVDDAFDDGDDAADALHEPAPHVAPAWDTLPTVAAPTLSLEVFPAR
GVPQLRRNVTAVRKLLKLGPDFVTVTYGAAGSRQAGTKELVTWIAQSGVPTYAHLTCQAA
SLCELDETIDELLEAGVTGILALRGDARDDGSGLVLPHATDLIARVSQRAEAAGQRIRIV
VAAFPTGHPDSRDLREDAENVARKQQAGADFAITQHFFDAEDYARFLDLVAATGATLPIV
PGLTPTTTVRRLERISELSGLTPPPALAAALDAAPDAQTRRDIAVQNTVELAEKLARAGA
PGIQLFTMNDEPTALRVFDALSSSPAGALGQNTGREPWLLNTQGPALKAALH
>A0A6A7K4P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalibaculum sporogenes|TrEMBL
MKITELFQRGEFPITAEVGPPKGFHIEHLMDEVNTYLKDNVTAVNVTDNQSSVMRLGSLA
TCKAFKDEGLTPIFQLTCRDRNRIALQSDILSAALFGIENLLLLTGDHTTLGDNPQSKPV
FDLDSVSLIHMVKTLEQGFDLAGNPLDGEPPKFAKGAVVSACSDSVDVQLAKMEAKVKAG
AEYFQTQAVYEPEKFMRFMEKAKQFGVPVMLGIVIPKNAGMARFMNDNVAGITVPQDMID
ELKKDKEKTKAGITGVEISARIIRECKEYCQGVHIMALGWESKVPDILKLAQI
>A0A1H0CC91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas jatrophae|TrEMBL
MPQSKTARQAIRVSFEFFPPKTPAMEEGLWNAITRLAPLRPDFVSVTYGAGGSTRERTHQ
TVARLLRETDLKPAAHLTCVDASRAEVDEVVRQYRDTGVRHFVALRGDGQGGAGSAYQAH
PDGYRNGAELTAGIKRIDPSIEVSVSAYPEKHPESPDVATDIEMLRRKVDAGATRAITQF
FFDNDQYERYAERVRAAGIFVPIVPGIVPIHDFTKISRFSAQTGASIPTWLARRFEGLEN
DAQTRSHVAAAVCAEQVLDLADRGVGDFHFYTMNRADLVYSICHILGLREDSTAVAA
>A0A4R4DTC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flaviaesturariibacter aridisoli|TrEMBL
MKVTEHLQQAQGRTLVSFEILPPLKGKGINALWEHLDPLMEYHPSFINVTYHRSETMFKR
TAAGTFDKVEVRKRPGTVGICAALQNRYKVDAVAHLICGGFSKQETEDALIDLHFLGIDN
VLVLRGDAPKNEAVFEPEPGGNAYAIDLLHQVQRMNDGIYLEEDLKNAVKTDFCIGVAGY
PEKHFESPNMRTDLAWLKAKVDAGACYVTTQMFFDNQKYFDFVKACREAGIDVPIIPGLK
PLTTRKQLSIIPRTFHVDIPEDLASAVLAAKSDADVERIGTEWLLQQSKDLKAAGVPVLH
YYTLGKPRVIADVCKEIA
>A0A2S2FES9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter defluvii|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLRVVHQELQLLKPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKERIAELLDLYQSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQRFCDKIRAGANAALTQFFFNPDAYFYFV
DRIQKEGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A419HQH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium YIM PH 21723|TrEMBL
MKSVVDRLRAKRPTFSVEFFPPKSAEAERSLWQAMRELESTDPAFVSVTYGAGGTSRDTT
VRITGQIAANTTLLPVGHLTAVNHSIAELRNVIGSYAAVGITNVLALRGDPPGDPQGEWV
QHPEGLLYAEQLVDLVQELGDFCVGVAAYPQGHPRSPDPDSDLRYFVQKLRRSDFAISQI
FFEVDEFLRLRDRVAAAGVDLDETPLLPGLMPITSLKGIQRIAELANMTVPSWLLDRFAP
YEGDAAAIREAGVELTTQDSQRLLAEGVNALHFCTLNKSNSTRDVLANIGLLPVRS
>A0A5C5QIT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas extremaustralis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKGAGIKRIVALRGDLPSGMGMASGELRHANDL
VNFIREESGDHFHIEVAAYPEMHPQAHNFEDDLQNFVRKANSGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCDRLLQGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>R7A9T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:43|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPDLCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A564VUI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium catenulatum|TrEMBL
MHSPMFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVS
EYGIPSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFEHASDLAA
YIRQQRPGMKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KARAAGVDAPIEAGIMPVMNAKSVLNMSSKCQSKIPEKLSIMLDKWGSDKALLKEAGIAY
ASEQICDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A3B8HU10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas sp|TrEMBL
MKIIDLYRQESPVLSLEIFPPRMDYPLETVFTTVEKLIRLQPGFISVTYGAGGSSRDRTV
EIAARIKNDYKVESLAHLTCVRHTREEIHQILQDLLGEGIINIMALRGDFPEEQENFQLD
QQEYRYAFQLINDARQLADFGIAAAAHPEGHPECRRLSEDLENLKNKVDCGVDFLITQLF
FDNRIFYDFVDRAMAKGINCPIIPGIMPVLNAKQIKKMIYLCGASIPSKLLSLVERYENI
PADMEKAGIEYASEQVLDLIDDGVAGVHLYTMNKPEQIAEIVNNIGINRS
>A0A2V7QTN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTITLRDLLNDGKVHVLDGAMGTMLYSKGFFLNVCYDELSVKQPKLVQEVHEAYVRAGAE
ILETNTFGANPVKLRTFGLADDTEQINRTAAELARKASAGRASVVGAIGPLGVRLEPFGA
LSREEAFAHFQRQVQGLVAGGVDGFILETFSDVDEIHQALRAAQSVSDLPVIAQMTIGDD
GLTHYGTAPETFAKQFAEWGADVIGVNCSVGPAGVLEAVEKLVKATDRPISAVPNAGLPK
DVGDRKIYLASPEYMASYARRMIEAGARVVGGCCGTTPEHIKKIRDYVASVVPRHQPVVQ
SRETVAPPAGVEEVPLAARSRWGAKLAAGKLVTSVEIVPPKGVDPTPMLEQCRALKAAGV
DAVNVPDGPRAQSRMGVLPSAILIQREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRN
ILIITGDPPKMGPYPEATAVFDIDSIGLTNLVYRLNHGLDPGNNPIGVPTRWAIGVGVNP
GAVELDRELSRFHWKVDAGAEFAVTQPVFDVRQLESFLKRVEAYRIPIVAGIWPLVSLRN
AEFLANEVPGVVVPAEVLERMRRAQDKGKEAALAEGVKIAREMFEQVKSSVQGVQVSAPF
GRVEVALEVFG
>A0A7Z9ILM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MRSLIEDGHIHVFDGAMGSVLYTRGVFVNICFDELSLRKPEIVRRIHEEYVAAGAEILET
NTFGANPVKLSSHSLGDRTEEINEAAAHLARDAAAGQAAVVGAIGPLGIRIEPWGPTERA
EATVFFERQVTGLLAGGVDGFILETFSDLSEIDCAFAAVRKLSNLPVIAQMTVGHNSKTA
YGHKASQIAEELTKIGVDVIGLNCSVGPAVMLDAIEDMADATSLPLSAQPNAGLPRTVRD
RKIYMATPKYMALYARRMIDAGVRFVGGCCGTTPDHIKHIRDTVRLVQPRAVTVRVPDVP
QDRLEILDPVPLEACSAWGRKLSQGEPVVSVEVLPPRGWDRNAIVDPARRLKVAGVDTLA
IVDGPHSRSRMGALSAAVIVEQEVEIEAMVHYTCRDRNMLGMISDLLGAAAAGIRNLLVV
SGDPSVQGPYPDMTEVFDIDSIGLTNVVRGLNRGVDPAGNSIGEPTKFVQGVVANPGALD
LEREVTRFRYKVEAGASFVVTQPIFDPETLESFLEQVHAWKIPVLAGIWPFLNLRNAEFL
ANEVPGVAVPEEIVDRMRKAQASGDEEAMDQGVRIAVEMIKAVRPLVQGFHLSAPSRRVD
VALRVLHEAGISPNA
>A0A2E3Y8U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MNRFLDALGAGPLLADGAMGSYIFELTGRLSEPNHVYESFSLDRPEVIRDVYLGYLRAGS
RCLTTNTFAANADCLAVDGLAERLVDLNRAAIDVAREAAEQYRASEGGEEIXVLASVGPT
TDPDQDDASTFDAYQEQLAAIAGADALLLETFRSLASLRQVLSTVAQIPNRPPIIAQMAV
QQDADGWSTSPSELVDAAVAGGAAVVGVNCCTPWDAETFVEQASQLAAVAEGRIRLSAMP
NAGGFQHIGNRYMTRVNPEFMGRWARTMTQRGVSLVGGCCEIHPRHVWEMNNYLAGWGTR
SAGVTVEGAPVKKPSDGRIKRDNGGFSRKIVDGEFAVSVEILPARGTAPXLLQRKIDFVG
XLAASGLADGLDITDGSRGIPLMPPGDFIHVVRERLGWQPGQDGLELMPHFTSRDLNTMG
LQARLVGYWANGIHNVILVTGDPPKMAPSYPPSTAVFDLTSVDLIRLVNNGLNAGVDFGG
QALGKHADPXTRFTIGTGFEPESLDLTAEMEKLTRKIEAGADYIMTQPAFAWEPLEVLSE
VRQSVPVLVGVLVLTSLDXALRMRQVPGVVVPEAVLDRFGQSDDRASQAQVGRDLAAEQI
RRIQSEEWAGVYLMSPASHDPVIDVLRAGXT
>A0A2E8QWA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MKSLVRDNRVHVFDGAMGTLLYSRGVFVNVCYDELNLSRPELVRGIHEEYINAGAEILET
NTFGANPVKLSSFGLEDRTEEINEQAAKLAVEASSRAGVSEQTKENGPEYFSGSTVAVAG
ALGPLGIRIEPWGPTSLDEAEAYFARQVDGLLEGGVDGFVLETFSDISELQCALRAIRVA
CELPVIAQMTVGPDGKTSFGTEPAHLAQAMEDSGADVIGLNCSVGPAVMLDALEDMAEVT
QLPLSAQPNAGLPRNVRDRKIYLASPDYMAQYARRMIDVGVRFVGGCCGTTPDHTRRMRD
SVAALQPKHPIVTIRDSANSSHSVTNPVPLDRRSAWGRKLARGEQVASVEIIPPHSWDAS
AVTSPARELKVSGVDAVSIVESPRSRSRMGALSAALIVEREVGIETIVHYTCRDKNMLGM
ISDLLGAAAAGIRNVLVVSGDPPVMGPYPDTTVVFDIDSIGLTNVVQGLNQGIDPGGNTI
GAPTEFVQGVAINHGAVDQERERSRFEYKIEAGADFATTQPVFSPEALEQFLDATTPEIP
IVAGIWPLTTLRNAEFLANEVPGVHVPTELVDRMRRAQLSGADAALEEGIAIALEMINAT
QGFVQGFHLTAPNRKVQVALKVLRESGILATA
>A0A3M8CJ12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus invocatus|TrEMBL
MTTSKQDLREYLQDHLLVGDGAMATQLHRLGVPVGVSFEELCLSNPRLVHEVHDSYYQAG
ARLLETNTYSANRDSLSRYGMEHKVTRINRQAVSLAREAAQGDAYVAGSIGSILAGRVRK
KVLDEYRDQYEEQAIALLHAGVDGLILETFLDLEELLLAIEVIRPLTPLPLITQLATLEV
GRTRDGYSLTEAFAQLKTAGADIIGLNCRLGPAEILRSFETVQAPKDALLSAFPNAGRLG
MTDGEYAYKSTAEYFGQSALRLREQGIRLIGGCCGTTPEHVKAMADALESLEPQARTNPD
EVPGERPLVSVTSVRDQDRPSIVDKVKSGTTIIVEFDPPRDLDADSFLEGCCELHKAGAD
AITLADNSLATVRMSNMALGAMMKSRYGIDPLLHLACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQNAQFIVGAAFNPN
VRQIDAAIARLEKKVEAGADYIMTQPVYDAESIKVVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSPEALERMKRVQGEDARREGIQIAKELLDTAVRYFQGIYLITPFNYYS
MATELIQYVRQQSAQLKVPVQG
>J2Z683|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loigolactobacillus coryniformis subsp. coryniformis CECT 5711|TrEMBL
MSFKEALQQQVLIADGAMGTLLYSQYGVNSAFEGLNLTHGGDILKIHQAYIAAGADVIQT
NTYAANRIKLNRYGLADKTKAINEAAVSLAHTAQIAAEHPVYVLGTIGGIAGVTDTEIEP
LTAEEIDAGVQEQATYLLQTQAIDGLLLETYYDINELKRALKIVRALTDLPVVANVTMYE
PGVLQDGTPLNTALQDLAALGADVVGANCRLGPYNMSRAFESVALPKTAALAIYPNAGLP
DVQDGKTVYDSPAEYFENYSDTFRRQGAHLIGGCCGTTPAHIKGLVAGLQSRQPVTTKKV
TLPAAEAVPTAADPRQHDFLQRVQHEKVALVELDPPKTFTTAKFFRGAQTLSQAGAGAIT
LSDGPLANPTISNVALAAQLKYQYGITPLVHLTTRDHNLIGLQSEIMGLHTLGIANILVI
TGDPAKVGDLPGATSVYDLHSVELMQMIKKFNAGISPTGRNLQEKTNFAVGGAFNPNVRN
VERACKMITRKTAYGADFIITQPIFDITKVHELRLALDEQGITTPIFVGVMPLLSFRNAN
FLHHEVPGIRLADDTLARMQQAEADGNEREVGLQIAKETIDAICADFNGVHINTPLRHHE
ISLELLNYVQAKNAVSV
>A0A7X8KR49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacteriaceae bacterium|TrEMBL
MKISDLFKTKKVVYSFEIFPPRPTSPIEVVYDALAKMQDLNPDFVSVTYGAGGSGPNSRT
CEIVSHIKENYDFEPLAHLTCINSVKKDIEDTLKRLHANQIENILALRGDRNKDGSVAND
FHYASELIEYVKQNPHFSVAAACYPEGHPESENLSKDIEYMKLKEDYGAEFFITQLFFDN
EDFYRFVEKVRAAGISSPIHVGIMPVTNTKQIERILSLSGSKVPHKLSRLLARYGSDKDA
MMQAGILYATEQIVDLLDNNVQGIHLYTMNSPSIARHITQNIDRLLYSENTSR
>A0A7K1ZKZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium SB0668_bin_1|TrEMBL
MSPRTMTFSLEFFPPRTALAEERLEANLPTLLALEPRFISVSCGAAGSSQEGTFELVQAL
RTNHRVTCCPHMSSVGRTRTRIARVVRAYAELGVRRCIALRGDKPDGYVPSEAHYTSSWE
LIAGLRDVVPEFEIGVGCYPEGHPEDRSPDDRFTILERKVEAGAHFAISQLFFETDAFLT
FRDGCARRGIAAPVWPGIMPIHNPTRVFGFADKCGAVVPDALRARFEGKSDEETFELARD
VVCKQALRLKAEGVEHMHLYTLNRHRLAAEIVRALKT
>A0A6G6VYG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. 4R-513|TrEMBL
MPADSSITDTVPFSFELYPPRSDAAAAELLETIRALAEAGPRFISVTYGAGGSTGGRSLD
ILRHVRATGVEALAHLTCVGNTYEGAARLIREFLDADITSFLALRGDPPAGVSEDDIFLG
DLESAAQLVQLIDRVQAERSPYTEASIPGVPGAVRVERRRRVDIAVAAFPNGHPRSRHPR
EHIDALLAKQAAGATFAISQVFFHADDYLCFVERARQAGVGLPILPGIMPIVSPVRLRRV
LELTGEELPGELAVALEVEPTPEGRRAVGIEHAARLARDVISGGAPGVHLYAFNSHDAVL
AVLRAAGILSHHPSELEAAR
>A0A6G2X9H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8381|TrEMBL
MALGTASTRTDRARTVRDMLATGKSTFSFEFWAPKTEKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVTAAGCETPVIPEVMPVTSVKMLERLPQLSNAVI
PDALKERILAAKDDPTAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A3B9JGV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacteriaceae bacterium|TrEMBL
MREKKLSYKEAVLSKEHFSVTWELVPGRGSTEPAQDQVIETARQAVEDPRINAFTITENP
SGKPAILPYPLAKQILDETGGETLIHFTCKDKNRNEIESQLHAMNRSKLNNLLVMTGDYT
TEGFGGRPKPVFDIDAVHTLRIIKKMNQGYEIPVRKGTKQLNKTDYFAGAVVSPFKSTEP
EQMAQYYKMHQKVDNGASYLITQLGYDARKFDELKRYADKYDIGVPLIGNIFVLSLPVAK
MMNKNLIPGCVVTDKMIKEMEEEKAKYPDHKERQLLRAAKLYAVLKGLKYDGATIAGHGM
SYKDLCYVLDKGEELLPNWQEIVKEFDYPMDNGFYYFEKDPVTGLNTDVPVDRTKTGHKR
NTLFDRMFGMVHSLVFKESAPFYPIVKFFAKKIDKNFLNKPFTWFEYYTKTFTNECRFCG
DCVMHEIGFQCPMSKCPKNQRNGACGGGRDGWCEVYPGKQKCIYVVMYEKLKAHKKEYTM
KLRYTPPCNWDLYKTSSWLNFFNERDYNYRKDE
>A0A2D6E9P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MAGRHLLERLSRGVLVGDGAMGTMLYAKGVYINRCFDELNLTEPDLVRGVHSGYVEAGAD
FLETNTFGANTFKLEPHGLGDRVPEINRQGAEIAREAAGEEVLVAGAIGPLGVPIEPIGR
IAFEEARAGFRDQAEALAEGGADFLIMETFHRLEEMREAIRGAREATDLPLVAQMTLTEE
NATALGDPAAQVAARLEEWGADVVGLNCSVGPRPMLKALEVVREYTARPLSVMPNAGMPR
LVEGRYLYLSSPDYFAKYARRFFQAGAKIVGGCCGTTPDHIRAVAAAARAIPRKTAALEP
ARTPVRLSPKVLPEAKAVPSRAKSAFAEALASGRFAVSVEVSPPRGPDPARVLERIRLLE
EAGVDAVNIPDGPRASARMSSLALAVLAGQETGIEVILHYCCRDRNLLGMQSDLLGAGPL
GIRNLLIVTGDPPKMGDYPDATAVFDVDSIGLLQIAGRLNHGQDIAGNPMSQPTALHLGV
GVNPAAVNLDEEVRRFEYKVEAGAEYALTQPVYDVSVLERFIRRTEHCRIPTLAGILPLR
SHRNAEFLSNEVPGMEVPRSILDRMKAAPTGAEGREEGIAIAKEALRECAPMVQGVYVMP
PFGKIDVALEVVAAVPPELRAPKQGM
>A0A7V2LNC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineae bacterium|TrEMBL
MKITDLWATKDKPTISFELFPARSEKAAANLARAIDALAALQPDFVSVTFGAGGSTRKGS
YQLVKSLIQDKGLDVITYFACYGLSPEEITSVLDDYQALGVENILAVRGDAPRDKEFEPH
PDSFAHATDLLAFLRPRYDFCIGVAGYPEGHIEATSKDKDLEYLKMKVDLGAEYIIANYF
YDNAFFFDFVERCRGMGIDVPILPGVMPVYSVKMMEMLAGLCGATITDELRQGIAALDET
DKGALTDFGIDFAVRQCTGLLEAGVPGLHIYTMDRSKSTVGIINRLRDAGLL
>A0A7C2BWU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MGATFLDRLHREVLLADGAMGTLLLARGVEPKALMEQNLTRPELIREIHLEYIRAGAQVI
ETNTFLANRLRLAEYGLESELEAINRAAVRIAREAVRMSGEEVFVAGSVGPLGALVKPYG
NLTLADLSAAYVEQIGILVDEGVDVIIIETHPSLLEALEAVRAARTVSPTTPIIAQMTFL
EDGKSKFGDDLRRSLEALAAADADVVGVNCSGPQMTYDIIVDFLTTTELPISIMPNAGVP
QFIGGRTIYLSSPEYLREYARRFVEAGANILGGCCGTTPEHIRAMSAVVRGQVPRRVRQR
AVVSVGGEEAPGASSTASLPTRFRERLGREFVVTVEVHPPRGVDYRAEIEMIRQLARCGV
DAVSIHDPPGARVSLSGLVFAHVVQTQAGVEAIWHLSCRDRTLAMVHSELLGAAVLGVRN
ILALTGEAASVGELPRAPSAHDVSATGLVKIIEGLNRGRTLMGNDIGTPTDFRVGVLVQI
GADDLEVELRKLEERVQAGAHFIVTTPVFDLERFDVFLQHIAAFRLPILVGVLPLKSARH
AEFLHHEVPGITIPEAIRRRLHRAQGDEATEGLRIARELIAALRPHVAGLHVIPPAERWD
ALPEFLRTCLPQERAAESLSA
>A0A7C2GIP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MAVLGILRAKADTGEKTFTVEISPPANYKTIVKTSEMVRALKDFDIAAIAVTNSTGGSFR
MNPLSVVETIRAWRPETPIVIHLTARDEGSVRSLYSRADEMDRKAVSDVLILRGDPTPQR
SREVDAFKFSTVELVRLLREYRDEQGYAIDLFVAGHPEYPPHALAKHMAYQRRKIEAGAE
GIIANIVTDPANYARYVEAARAQGIAVPILPSVIPLTSVRRCLFLHTTLHIPVPQWITER
LNEARSKEEAARIGLEITIGIVERLLREGAPGVNFNLIFPQDIASVADILRAVRGHATIW
EKYKIEDPEEIEYYSQLRGRLL
>A0A3N6XDH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas jandaei|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLGPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPEMYATDLVALLKAEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLENDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQP
>A0A5A8AF11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. SN22|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTAGGHASAMDLVHQINNLGRGKYLHNEEKECEEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVKKAREMGITVPIIPGI
KPIATKKHLKVLPQIFKIDLPEELINEVEHAKNNEAVKQIGIEWAIAQCRELLDFGVPVL
HFYSMGKSDNIKKVAGALF
>A0A017HD33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limimaricola hongkongensis DSM 17492|TrEMBL
MTRALKEVLMSLLTFRRAAPAPAMPGGDFTARASIEVMPRTAAKVDSFRAILPEGTRVYI
AHIDGTPIEEMVATAARIASEGFAVMPHFPARSIESRAQLGDWIARYQGEAGVTEGLVLA
GGIAQPRGEFHSSMQLLETGAFDAAGFDRLHVAGHPEGNRDIDPDGGDAVVRDALRWKQD
FANRSDARMALVTQFVFDAAPVIGWARTIRAAGIDLPVHVGLAGPAKLQTLIKYAMACGV
GPSLKVLQKRAMDVSKLLVPYAPDDIAAALEHARAAEPGLGLEQAHLFPLGGINASAEWL
AARHPASRIAAN
>A0A0F3RT39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Levilactobacillus spicheri|TrEMBL
MSSIQPPTLSFEVFPPQSPADRASLLATLDQLRGCHPAFVSVTYTNHQLDYEQATLGLAQ
TVQARVGCPVMVHLLAAYTSKTQVSRILADLESLGVTQILGLRGDLDPGQTPGTDFPHAS
DLIRFIKARNPQFRLAGAGYPAGHPESPTREADLAHLQEKVAAGCDRVMTQVFYDNQQFD
RFRADCVARGITVPILAGILPILSRQQALRVETDFGARLPQPLRTRLDRVWDDPVAFRAV
GLDYAVEQITDLVAHGVAGIHLFTLNQASTVAAIYARTAALFEK
>A0A1G6U255|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter soli|TrEMBL
MKITDHIKNAKGKTLFSFELLPPMKGQSIQWVYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARQAEASFIPTKGGHHYATDLIQHIKDHNNGKFLHEDIDTYKSDFCIGVAGYP
EKHFEAPNLNADFKYLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLKQLTVLPKIFHLDLPNELTEALSYAKNNAEAKEIGTAAMIKQCKELMEFGAPVLHF
YTMGRPEQTKEIARAIF
>A0A1I1BHM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. 344|TrEMBL
MATHNFSIEFFPPKTPEGAEKLRATRAKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEEAAPHLSCVGGSRDSIRAVLADFKAAGVKRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGANAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAATTALWQRLVK
>A0A7X6Q4G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
ITNYTQLARFSNMCGAEIPRWIAKRLQGYGDDVKSIRAFGHDVVTKLCDELRSGGAPGIH
FYTLNQAEPVLKIWRELEGKS
>A0A1F9NNJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium GWB2_56_26|TrEMBL
MIRNFNDDISTPEKFVVTLELVPGRESSGRTTDMIKGISKEAAQDGRLTAVSITDNPGGN
PALSPDMLGYEILDSGMDVIVHFTCRDTNRVGMESRALQLARMGMKNILALTGDYSGKGF
GGKGTPVFDFDSVVLTSMFKDLNRRLIKTGHSSIFVTGCAVSPFKYTEAETYVQYRKLER
KIEAGASFTITQLGYDVDKYEELLHFKKDKNIDIPAIASLYLLDKRSAKPMNAGRVPGVV
VTEKLFNKVMQEWEDPVEGRNHAIERTARLGVVLKGIGYNGIHLGGIHDSFDTVGRILDR
MEAIEHNWRDYVEEFRENEPARFYIYKKQESARESAQKEKIKMKITDNCHYMFLKTAHDL
FFDKGASLAPVYKRISSSLDRNKKSWVLKRFLEDPFKKLLLSCQSCGDCGIQHVGFLCPE
SGCPKHTRNGACGGSNNGYCEVNKDTLCVWVRAYERMRKHGETQKLTGEFVPPRLWELKD
TSSWINFHLDRDHQKPKEEPKAKAL
>A0A7W0KHC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexia bacterium|TrEMBL
MAHPLIERLTTGVVLGDGAMGTMLFDAGHAADECLESLNATAAETVAAVHRQYINAGADV
IEANTFGGNRFRLAAHGLQDQARDLNKRGVRLAREGREISGTSVLVAGSIGPIGRTIEPF
GRLSRREATGGFREQIEFLLEAGVDLLVIETMGSLGEMECAIDAARACSDLPIVAMMTFA
EDGRTLSGRQPEEVVRDLAERRIDVIGANCSVGPQRLLGVIGQMRAELERLPEGVPAPFL
ACVPNAGWPSRVGGRIVYQSSPEYFADFAKAAIDAGARLIGGCCGTTPSHIAAMRVVIDE
HNAANGAQESETLTTVKPGAATTRPSIVMEADEATELHRKLGKTFLKCVEVDPPKGLNPQ
KALEGARLLKSVGVDAINVADSPMARVRMSAMTLCYLIQHEVGVETIIHFTTRDRSLMGL
QSELLGAHAAGVRNILALTGDPPSLGAFPASSGVFDVDSIGLIRIIKEMNDGSDASGASI
GRSSNFTIACAVDPNRSDLEDEACRLRQKIEAGANFVMTQPIFDVDVWTNFLNVFGAERL
PVPVMIGILPLQSTKHAEFLYNEVPGINPTENARERMRLAGANGRTEGVRMAQDLLQHLV
PHAQGVYLMPSFGRYEVAAEVLEVL
>Q1AXZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129 / PRD-1)|TrEMBL
MRGEPAARRLLEEARYEVIPLAGTEEAVERWLISRRAEEQKKTTITITASPTRGIEPTIA
LTERLGAKARRRGGEPSSLCVVPHLSARLIEDEHHLEEIVARLKEAGVEEVFVIGGDAKE
PRGRFHDALGLLEALEELGRPFERVGIAGYPEGHPSIERAELERALRKKALYASYVVSQL
CFEAKKVLLWARRVRELGVGLPVVVGVAAPIDPKRLAGVAAKIGIGDSARFLRKQRAKSL
LRLLSPGRRRSALSLVYEPGGFLEELVEEGSREGLLASSGGTEEGGGMISGLHLYTFNDL
QRTLEWVREEKKMAQREGEKRRRG
>A0A5C9B6M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MAERTFSIEFFPPKTPEGMAKLRETRRQLAQLKPKFFSVTFGAGGSTRDRTLETVLEIQA
EGLAAAPHLSCIGSTRDSLREILDTYRAQGIRHIVALRGDLPSGMAEPGEFRYANELVAF
IRQETGDWFEIEVAAYPETHPQARNYQEDLRNFQRKVAAGANAAITQYFFNPDAYFNFVD
DCAELGVSLPIVPGIMPISNFSQLSRFSAACGAEIPRWLSRKMESYLDDTASIRAFGLDF
ITGMCEKLLDGGAPGLHFYALNQAGLTSTIWQRLGIEK
>A0A7C2WPY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermorudis sp|TrEMBL
GDHPRFGTHPHAKPVFDMDSIHLVRVIRNMRDHGVLLSGEPLKVPPRVFVGAVENPFAEP
FEFRVVRLAKKIQAGAEFIQTQLVFNVEKFRRWMRLVVDAGLHEKVYILAGVGPIRSLRA
AEFMRDHVPGVEVPEELVRRMRDAADQREEGYRIGLEIMQQVREIPGVAGLHIMPMDWEE
AVQRYVTDLGLYPRPSVTEPTGATASTPSS
>A0A7V3YC32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKIPFESYLQDHCVLFDGAMGTYIYQQGVFIDKCYDELNLSNPDLIRKIHREYRNAGAMV
IETNTYGANRIKLQRHNLADRLEEINRQGARLAREIIGENGYVAGSIGPLGVGIAPWGEL
ALEQVGEIFFEQAKALLEGGVDLFILETFHDIREIEQAVKAISGFEKPIIASMTVQEDGK
TKYGLDVEEIATRLSQLPVTAIGLNCTVGPKPMLDFLERMIKCTDKPISIMPNAGRPQLV
DGRMFYMSTPEYFCVYTKRFIETGARIVGGCCGTTPDHIRKMAEAIAQKETRQGLRIQVH
EMPSVQLELKEEIPVEKKSELAKKIVQNEFVRIVEMVPPRGRDISKQLSSAEKLKASGIH
AINIPDGPRASARLNGMVLATMLQSKVGIEAVLHIACRDHSLLGLQSFLLGASVLGIKNI
LAITGDPPMLGDYPQSTAVFDIDSIGLVHVVRKLNRGVDVGNKPIGEPTAFFVGVGIDPN
SVNPKRELERYFQKVDAGAEFA
>A0A1J3ZZT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. HMSC036D05|TrEMBL
MSQFLKHLQNNVLVADGAIGTILYSEGLDTCPEAYNLTHPDKVEHIHRSYIEAGADVIQT
NTYGANFEKLKNFGLEHRVREIHKAAVQIAKRAANEDTFILGTVGGFRGVRQEEISLSTI
QYHTELQIDTLINEGVDALLFETYYDLDELKNIVVATRRKYDIPIIAQLTASNTNYLVDG
TEINEALKQLVECGADVIGLNCHHGPHHMQRSFSHIELPEQAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIRYIKSAVQGLTPVKDKKVIPITKKS
NRKPTSVMKQNLTTKVKNGPTVIVELDTPKHLDTDTFFDNVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQRYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A6L4ZR66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
SDLSEINQAIRAIKELCDLPIIAQMTIQTFGKTAFGTAPETFTTQLDSLGVDVIGINCNV
GPQDSLDAIQIMSTVTERKLSIQPNAGLPREVDGRKMYMCSPEYMAKYAKRFIQSGVKFI
GGCCGTTPEHIKLIANAVKASSPQRVAVSVSVPKEQAQKVEVVPVAERSNFARKIASGEF
VTSVEIVPAKGCDAAKMLESVAELRDAGVDAVNIPDGPRAQSRMGALTTAILIQQKVGGI
EPVVHYCCRDRNLLGMMSDLLGAAALGINNLLIITGDPPKMGPYPEATAVFDVDSIGLTN
MVTSLNHGLDIGSNPIGKPTSFFIGVGVNPCAVDLDTEIRRFEWKVDAGAQFAVTQPIFD
VEQFFTLLKRIEHCQIPIIVGIWPLVSYRNAEFLSNEVPGISVPPHILERMRKADGQEAA
RQEGLTIAREMLKEVKSLVKGVQVSAPFGRVPYALDVFSVLK
>A0A7Z0NHF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MSSKKVVSLEFFPPRDAAAQEKLAESAGKLLALQPAYVSVTFGAGGSTRTGTADTVRMMQ
KLGCDAAPHLSCIGSTRSVLGNILDSYREQGIKRIVALRGDLPSGMGGDPGELHYASDLV
SFIREHSGDWFHIEVAAYPEMHPQASSAQADLDRFIDKIQAGADSAITQYFFNPDAYFDF
VDRVRAKGIDVPIVPGIMPITNYAQLARFSNMCGAEIPRWMRLRLMDFGDDKASIKAFGI
DVITRMSQRLLDDGAPGLHFYTLNNADVTTAIWKQLDVGSGPELNMGSDPVRGLTP
>A0A1C1CR04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cladophialophora carrionii|TrEMBL
MHISKKLAQAHQSNKPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
QLTCEMVNAAQSHYGLETCMHLTCTDMERTQVDDALRRAYKAGCTNILALRGDPPRDQEK
WEVKEGGFRYARDLVKYIRTKYGDHFDIGVAGYPEGCDDHRDVDVLIDHLKEKIDAGATF
VVTQMFYDVDIFLDWVKKCRDRGIHVPIIPGIMPIHTHAAFVRRANWTKCHVPEDWYKAL
EPVKNDDAAVRAVGKELVAEMCRKILDAGILHLHFYTMNLAQATRMVLEDLSITPSTSGL
ALEKPLPWRKSLGLNRRDETVRPIFWRNRNASYITRTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANIKLWGKPKSLREVTSLFVRYLQGDLDRLPWSEGAISTEAESIKDDLL
SLNKRGFLTINSQPAIDGASSTHPVHGWGPAGGWVYQKAYLELLVFPSMFQKVIERLDAN
KNLTYYAVNQKGELLTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WSKCYPAGSGSRKLIETIMGECYLVNIVNNDFHQTHEIFKVFDGLEARDLDLVFEGTDAS
DHTNGTDSTREVLNGDAPVAEVEKSIANGEERKVPFPTNGVALKN
>A0A316AWH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter iranicus NCPPB 2253 = VKM Ac-1602|TrEMBL
MSEQRSSADPACSSVPFSFEIYPPRTPAGALALTKTVDRLAAVRPDFVSVTYGAGGSSRS
ASLEILRYLREHTSTPALAHLTCVGSTHAEASSLVREFLGAGVTRFLALRGDPPVGTPEG
DPFLGELGSAAELVQLIHRVQAEREPYGAVAVPGLPNAQRVEVGARPHAEVAVAAFPNGH
PRSRSRTQDIDVLLAKEAAGASFALTQLFFHADDYLRFVDRARAAGLRMPIIPGVMPVTS
PGRLRRMLELSGEDLPAELAIALDVEPDDEVRARIGVEHAARLVRTLVAGGAPAVHLYAF
NRHEAALAVLAESGLLPDSAPSLPSAANLPTPSP
>A0A258Q8V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halothiobacillus sp. 28-55-5|TrEMBL
MTIPLSCEFFPPKSDDGAAKLRAITTELATALCPEYFSVTFGAGGSTQERSFATVSAIQL
ESGVPAAPHLSCIGSTRAGIAAILDQYQALGIKRIVALRGDLPSGMRDPGDFRYASELVA
FIRQHSGDGFHIEVAAYPEFHPQSLNAKADLQHFKHKVDAGADGAITQYFYSIEAYSRFV
DDCDKRQITIPIVPGIMPINNYTQLARFSDACGADLPRWLRKRLEAFGDDMDSLRAFGHE
VVVNLTADLVRVGAPGLHFYTMNQAAPIIALCQDAGVHPA
>A0A3G8LYB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella livingstonensis|TrEMBL
MAFHHAQHAQSLNQSLSELNDINVSFEFFPPSTPAMEEILWNSIRRLEPLNPKFVSVTYG
ANSGVRDRTHSVIERIQKETNLLAAPHLTLVDASDEELVELAKHYWNSGIRDIVALRGDL
PDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDARNAQADLINLKKKIDAGANRAI
TQFFFNVESYLRFRDRCVTAGIDVEIIPGILPVTNFKQTKRFADMTNVAIPHWLHRQFEG
LDDDPATRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A1X9SS94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter lanienae|TrEMBL
MLKNKIKQGKSGIVLYGLTPPKISLSHDEAKEIALRQLSRLDGIKIDGLVIYDLQDESNR
NSSNRTFEFVHTIKPEIYAKDYLQNRYEAVIYKAIGNYNEAEFKEFLQTHSDAISVFVGA
SSAIDTPKLSLNDAYKMKKEIANDLTLGGICIPERHTKKHDEDLRVASKRVKGCEFFITQ
AVYDIETAKRFLDDFAALGIRNTPIIFTFTPCGNIKTFEFMQWLGISVSELSRHRIFDSD
DALESSVKLSLDMFEFLYKYGLAKGVSVGANIESISTRKVEIDASIRLLKGIIAIIENHS
LENTKSKIQSASKFDE
>R6VJ14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:227|TrEMBL
MALSRNGCVMPRELCKIISKNWIFPNPFDKELFDADVEGKKARFKEAGIEYTMKQIDEYR
ALGVNGIHLYALNKWKDVSEIIDRSGLRTLV
>A0A426QKE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiohalobacter thiocyanaticus|TrEMBL
MKTQQKYDKSFSFEFFPPKTEEGAKKLRLARSRLDKLNPNFYSVTFGAGGSTQEGTFETV
AEIIKSGTDAAPHLSCIGSTRDNIRTLLQRYKDAGVRRIVTLRGDMPSGMRDTGEFKYAN
ELVEFIRAETGDSFKLEVAAYPEFHPQAPTAFEDLNNFKRKVDAGANTAITQYFFNADAY
FRFVDDCEKMGIDLPIVPGIMPITNYKQLARFSDACGAEIPRWIRQRLIAYGDDMESLGK
FGEEVVTDLCQRLLDAGVPGIHFYVMNRSAPTIAIWKNLGLPVRE
>A0A0Q6FZ84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Leaf453|TrEMBL
MAIHTLYPAERGNLRLSFEYFPPKNDEMEAQLFQTVSELAAFNPAFVTMTYGAGGSTKAR
SLTAVRRMINEEGFANTAAHLTCVGAPRAEVDEIVGEFIESGVRHFVALRGDPQGGIGSR
YEPFPGGYENAAALVASIRARGDFEISVSAYPEKHPESPNVDADIDMLKRKVDDGATRAL
TQFFFDNNDFERYLERVRRAGINIPVVPGILPINNLAQVRKFAGLCGATVPDAIVTRLIH
LDEAPEERFKEATLIAAEQIVDLARRGLRDFHVYTMNRSPLVSAVCDLVGFERVKPAAVQ
ATGAAA
>I8WTZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei CL03T12C01|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKNGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNIEQDLYWLKKKVEAGADYVVTQMFYDNQKYVAFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAIKCKDDKEARALGIEWCVNQCRELIAYGVPGIHF
YTVGAVENVKEVAAAVY
>A0A1Z4VV45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiohalobacter thiocyanaticus|TrEMBL
MKTQQKYEKSYSFEFFPPKTEEGAKKLRLARSRLDKLNPNFYSVTFGAGGSTQEGTYETV
AEIIKSGGDAAPHLSCIGSTRDNIRELLQRYKDAGVRRIVTLRGDMPSGMRDTGEFRYAN
ELVEFIRAETGDTFKLEVAAYPEFHPQAPTAFEDLENFKRKVDAGANTAITQYFFNADAY
FRFVDDCERMGIDLPIVPGIMPITNYKQLARFSDACGAEIPRWIRQRLIAYGDDMESLGK
FGEEVVSALCQRLLDAGVPGIHFYVMNRSAPTIAIWKNLGLPVRD
>A0A4Q3XSN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MFDIDAIGLCRVLRRFNEGLDLAGYGVGVKCGFTIACAYNPNAIDQAEEDDRLRRKADAG
AQVIYTQPVFDSAALEKSVTMAETVGLPVLVGLMPLRSTRHAEFMHNEVPGVRVPQALRD
RLASAADDAAGLEIGIESAIELRTEIGHVAQGLYLMPPFGNAAIATRVLGGPGLPRVVEA
SR
>D0N474|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora infestans (strain T30-4)|TrEMBL
MKVIDKINASLERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMADADIKKALDQAKDAGIQNILALRGDPVRGATS
FDECDRGFSHAVDLVRYIREKYGNHFCIGVAGYPEGHTEFKDKKADIQYLKEKVDAGADF
VITQLFYDVKVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTSFCNTHVPDEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRASESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSNTSTPRERRAMWGDAPASKEDVRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGALSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
PSMQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEQGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEPSISPATSP
>A0A537GVJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MRLSDRARHHNLVTVELIPDRVVPSDLSLLRGRVDAITVPALRNGHDDPSYPKSFSITPQ
RRSLASASIINRAGITAVPSLTCRDCNTSDLSAIANHVVQGLRNVLIVYGDPFPQPHPGS
YQFAKTNELIREISSLNGGNDPCIGAVTNQHADNRESEISRTISRVDAGADFIVTNVAFD
SESVLEHRDALLEAGLNVPLFIQVSIPLSLDNVLFVSQKFDIPVPVHIRKKLLDDPTGGS
LAVAAEAYEALRDEANGIHFSYLFRRRNPIPTYCHLLETIGIEGPTLAPLATSAVKTYPV
A
>A0A7C5ZY99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MFISLEVTPPKKGVEKVLNTVLRAKGLVDAINVTDTPLGQPRIPGFIFALMIKERLGVEP
IVHYKTANMNLTGLKSVLYGCVAAGVKRFLFMTGDKPAEGSLISDVSPEDLSAWARKELS
VEAGLALGWPISVEKIALKLSAKPDYVFTQIFLTIKDAERFREMFDEAAEETGWRPPVYC
THLVHCEENLATLKEVARLMGFEAPGFKVGVEANVSFLRELESFFNGFMISSPGGYEHAI
ELAEALRRS
>A0A8J6LY55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neptunicella marina|TrEMBL
MLSYAQGIDALNNSLSQLKGINVSFEFFPPNSEQMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHEVVKRIQTQTGISAAPHLTCIDASRDELKAIAQDYWANGIRKIVALRGDLP
KGMDKPDMYASDLVGLLKDVADFDIAVAAYPEVHPDAPNSQFDLLNLKRKAEAGATQAIT
QFFFDAEVFLRFRDRAAAAGIDIDLVPGILPVTNYKTLVRFAGMTNVNVPDWLHKMYDGL
EDDDQTTRNLLGASIAMDTVKILAKEGVRDFHFYTLNRCELSYAICHMLGLRTQA
>A0A537EFD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MRLSDRARHHNLVTVELIPDRVVPSDLALLKGRVDAITVPALRNGHDDPSYPKSFPVTPQ
RRSLASAAIINRAGITAVPSLTCRDCRRADLSMIANQVEDGLGNVLIVYGDPYPEPRPGT
YEFTKTNELIREISSLNGGRHPCIGAVTNQHANDRENEISRTISRADAGADFIVTNVAFD
SESVLEHRDSLLEAGLNVPLFIQVSIPLSLDNVLFVSQKFDIPVPVHVRNKLLNDPAGGS
LAVATEAYEALRGEANGIHFSYLFRQRNPIPTYRHLLETIGVRGPELAPLAASTVKTFSP
S
>A0A537HYV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MCRRVPSWHGRSGLRLARLHELVGRKRVVTVELIPDRVSPADLGILRGRVDAVTVPALRN
GTADPVFPSGHHVSPQQRSIAAATLLRGTGLDAVPTITCRDSTVADVFSRLSDLLSVGID
NLLVVYGDPSGSAFDRYEMRASHHLIDWVDRTSNGRFSVWAITNQYHRDQEREIARTIIR
QEAGARIVLTNAVFEADGVLEYRDALRDAGLSVPISVQISVIHSLENLSFVSQKLGIPVP
IGVQRRLRRDPGAGVEVAADAYRALKSEFDGVHFSYLYRKQSPIPVYTRLLDLIGIPFQA
PGLNGELMAPDQLVR
>A0A497KSD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
VGDNPQAKPVHDLDSTQFIYMIRKIVDEGVDLAGKKIHNPPKFHVGAAANPNADPLEPEV
YKLIRKQNVGVDFIQTQSTYDIEVIKRFLKEVDSVGVKVPILIGVTPFKSIKMMEWLVKF
VPGITVPSEIQERLYKARKISKEKFEDENIEIFSELCREIRKTTNAAGIHMMAIGFEWVV
PPILERAGIKV
>A0A868AFX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Canicola|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A352T6H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKVTEILKQDKPTISFEVFPPKKDTDFADVEAAATSIAELNPSYMSVTYGAGGSTKGLTI
KLAEGIQNKYNVPTIAHLTCVCADNAGISQALEDMKAAGIKNILALRGDIPKDYAGEIFT
EFAHASELVKLIKASGDFCVGGACYPEVHPDSTDKKADIDGLIKKVEAGCEYLTTQMFFD
NNIFYNFMYRIREAGIMVPVVPGIMPITKRVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMRQAGVLYATDQIIDLIANGVNHIHIYSMNKPEIARAIYNNLSHIII
>A0A3M5VU69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. syringae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSTEDLRKLLAQYKDAGITRIVALRGDLPSGMGMASGELRHANDL
VKFIREETGSHFHIEVAAYPEMHPQARNFEDDLQHFVNKANAGADSAITQYFFNADSYFT
FVERVEKLGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLQLPR
>A0A0S2ZCV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium hwasookii ChDC F300|TrEMBL
MKIADIYKSKNLTTSFEVFPPNDKVGLEEVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHFTCIGSKKEEIDRVLEDLERNNIENILALRGDYPIDRELEPGD
FNYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVDAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A2A2VLP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. UFLA03-84|TrEMBL
MTQTISSVPNGQRAPKAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTISRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAGIKRRHADIEISVSAYPEKHPEAKDFDADIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRTGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A1Y2IZT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trametes coccinea BRFM310|TrEMBL
MKISKKIEQAAKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
ELTAELVKTCQKLIGIETCMHLTCTGMPKEKVDIALREAKQAGCRNVLALRGDPPVGKEW
EPVENGFRYGVDLVRYIRAQYGDYFDISVAGYPQTQRLPPEEREREMQYLKEKVDAGANF
IFTQMFYDVDMFVEWVKAARAAGITVPIVPGIMPIQTWNGFQKATTLAKITVPQAFLDEL
EPHKNNDEKVREVGTKLVADLCRRILAADIGIKGLHFYTMNLEKGCRLLLEELNLVPRIE
VIKPLPWRQPTKQSLTPNRRTENIRPIFWANRTRSYLSRTENWDEYPNGRFGDSRSPAYG
ELDGYGVWIKQSKEDALRLWDTPTSVDEIRQLFAKFCKGELSALPWSDTAPSSETSVIAP
QLAKLNELGFLTINSQPAVDGARSDDRIHGWGPANGYVYQKAYLEFFVSPELLDLLIPHI
ERDINITYYVINNRGDLRTNTHSDGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYEL
GRQWAKVYEPESPTRKLIDGLMDSYYLVNVVHNDYKKPEAIFEPFYKAGAEYAAKYGSSA
LQPLSSAEGANTNGHAN
>A0A7L1TFA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aramus guarauna|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETVLHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYALDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLR
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEELEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELVN
>A0A5C7PSH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
GDCALSVTGLACPMGCGKQMRNGPCGGVRANGHCELRPGQRCTWLEAGEGDLRMQGGARG
EHRPSWRERVAPLDRRRAGQSSWIRVISADQARRAAGPGIAQVAAPTESLDLMDPVRPSG
PFEQACREWHRSGRFIVTVEIAPPDSPDPAALLQRADRFAGLVDAINITDGAGANCHMSS
VAAASVLAAAGHTPVCQVGCRDRNRIALQGDVLGAAALGVRNVLCLTGDDVSQGDHPEAK
PVFDLDAVNLLHILRGMSERGEYASGRKLEQAPRLFLGATANPFVPPYADRVANLERKID
AGARFIQTQFCFDLGLIEDFMREVRARGLHERAAIIVGVGTLGSAKALRWMAEHVPGVHV
PQAVTERIAAAADQKAEGRRVAIETIHALRRIEGVAGVHLMGHKNEAALAQIIAESGLRQ
APQPAAVA
>A0A7U9FT65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli TA206|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7V9RJE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MTVNVSFEFFPPRTPEGVMKLRAVRRELTTLKPEYFSVTFGAGGSTREGTWNTVVEMQDE
GLSVAPHISCIGTTRESVRTLLAGYRERGIRRIVALRGDMPSGAAGGAGDFRYANELVEF
ARAETGDWFHITVAAYPEYHPQSHSPVADLQSFVRKVDAGADSAITQYFYNFDAYARFVD
DARGLGCNVPIVAGVMPIASYTQLARFSDTCGAEIPRW
>A0A6N8WA75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineaceae bacterium SB0665_bin_25|TrEMBL
MVNSDQTPSPGDWELQSGESRLLQVLEAGHFAVTAELNAPDSADPKDVYANLAELGDVCD
GINATDGSGANCHMSSVACCALMARAGYEPVLQMGCRDRNRIAIQGDLLGAAALGVRNVL
CLTGDDVSAGDQPEARRVFDFDALHLLRTARIMRDQGVLLSGRKLTTPPGFFLGAAANPF
VPPQDLRHLRLAKKIEAGAQFIQTQYCYDVPIFESFMRRARDMGLHEKVYLLVGVGPLRS
ERAAEFMRSRVPGVHIPDAVVDRLAKTPRKRKRAEGIRICVEIIEEVKQIEGVHGVHIMA
YRQEEAVPEIVERAGILREKPKK
>A0A0C1RNH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp. SC_K08D17|TrEMBL
MRENLFKEALLNPSVFPVTWELVPGRGAKESAQEKTLSLAKQAAESGKICALTLTDNPGG
TPAMSADFMGGEIVKLGIEPLVHFTCKDRNRNQIESQLYALDRAGVRNILVMSGDYPVSG
YGGRPAPVFDLDPIHTLRLMSDMNKGLTYPGIKGNISHQSSDFFPGAVVSPFKATEAEQM
LQYYKLRKKIDAGAQFIVTQLGYDVRKFHEVFLFMKQNGLNLPLIGNIYILPYGAAKMMN
RNELPGSVVTDKLLAELDRERNESDKGEGARILRAARMYAIMKGMGFSGVHIGGHNIKYE
QVEKIISQGEALISQWADLVRYFDYPIPGGFYYFEQDSKTGLNLDKPTTRQSRPLDATVG
LSYGFSRFFHNLMFDPGKKFYGVMKGLSGKVAGTKIESIFRKLEHWTKVVIFDCKDCGDC
ALIDVAYLCPMSQCPKNQRNGACGGSFEGWCEVHPGKKQCVYVRAYARLKKHGEEAQLEK
NIVPPCNWDLYQTSSWINYYLGKDHTSKKQNNS
>A0A7W0GN03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MDNISFEFFPPRTPEGDAKLRNVRAQLAALKPEYFSVTFGAGGSTREGTLNTVMEMHRDG
LSVAPHISCIGTSRDSVR
>A0A7X4Y2W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermocrinis sp|TrEMBL
MKVGELLKSEFSVSFEFFPPKSPEGEKELFETIKELEALKPTFVSVTYGAGGSTRDRTRR
IAYRIHTETKLTVMAHLTCIAHSKEELLEILQDYKSIGIENILALRGDMPKGDFQAPKGA
CKYAVELVRFIRENFDNFFSVGVASYPEKHPESPNMEWEIRFFKEKVLAGADFSITQMFF
DNSYYYRFVERCHKEGINVPIIPGIMPITNFYQIKKFASMCGATIPQGLVDTLEPYAEDP
EETTKRGVEFAIRQCEDLIANGVPGLHFYTLNKSKATLLIYQAIKHLIPPKVLSRLF
>A0A7T0KFM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium lizhenjunii|TrEMBL
MPARMSASAPIDHLLDQPLGYPTADPAPSQHPTRVAMSFEVIPPRNEDDASRLDNLLDTL
AQYNPDYVAVTSSQRSGWLEGTARFIERISTTTNMRPLAHLACTAGPVNELSGWIDRLVD
SGVRGLLALRGDLPPGEDRLPPGYLPHADSLVRLIRQRESEQLARLAAGRIAVGVACYPN
GHSESANTEEDFDVLLAKQRLGADFAITQLFFDAEDYLRFLQRARLAGVRIPLIPGIMPV
TTPARLERMSQLSGIPVPDRLRQRLESNPDSGLEITVELARACLEGGAPGLHLYTHNDAP
LTTEIMQRLGV
>A0A2H0Y0P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium CG08_land_8_20_14_0_20_45_22|TrEMBL
MSRVKFLDFLRDNIVLFDGAMGTSIYARGIYINRCYDELNLSKPDLVKEIHLGYVQAGAD
VIETNTFGANRFKLSAYGYNEELYAINFRGAHIAREVAGENLWIAGSVGPLGIRIEPWGP
TSEGEAEEAFGDQIKALADGGVDLIILETFSDLNEIHQAIKAVRRVCSLPVIAQMTIDEN
GNTSYGTPIEQVAQQLTKFEPDIVGLNCGVGPHMMLSSLERMIPMTDLPISIQPNAGFPK
KIENRAIYLSSAEYMAEYARRFIQAGAKIVGGCCGTTPEYIQAMRSAIQSLIPGRKGHRI
DIKPATIPGVNPVPIEQKSKFATKLASREFVTSVELVPPRGIEVSAAISATRILREVKVD
SVNIPEGPRALSRMGATYLSKIILDEVGIEPIVHYTCRDRNLLGIISDLLGIHALGLRNL
LLITGDPPKMGDLPNATAVFDIDSIGLVNVVNRLNHGIDLGGNPIGRPTEYLIGVGVNPG
AIDLDNELRRFEWKVKAGAEFAITQPVFDVDILFSFLERIRPFGIPIVAGIWPLVSLRNA
EFMNNEIPGTHVPDEILKRMASAQTRESALNTGLEIARETIQQIFPSVNGVQISMPFGKI
DTVLKVLDILPALKSVNNSITDVK
>A0A2W2BXG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora deserti|TrEMBL
MALGLPSVLPNPQPAIGELIRDCQPTFSFEFFPPKTDQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPDGVLYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTKYFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PAALAERFEKVADDPEAVRRLGVEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLQ
AGARV
>N6ZNV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera phenylacetica B4P|TrEMBL
MKPEISIEFFPPTTAEGADKLHATREKLAALKPAFFSVTYGAGGSTRERTFSTVKEIAAA
GHEAAPHLSCVGSSRDSIREILQEYADAGIRRIVALRGDLPSGAGAAGEFRYANELVEFI
RAETGGRFHIEVAAYPEWHPQARSPRDDLAAFKRKVDAGADSAITQYFYNLDAYLHFVDA
VRKMGVDVPIVPGIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDSDAIRAFGLDVV
TDLCEKLLAAGAPGLHFYSMNMAGPTTEICRRLGLTT
>E5B0F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia amylovora ATCC BAA-2158|TrEMBL
MSFFHANQREALNQSLAEISGQINVSFEFFPPRTGEMEDILWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELRSIAEDYWHNGIRHIVALRGD
LPPGGGQPEMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRVPGWMTSMFA
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPGLALAA
S
>A0A1M5NNZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter caeni|TrEMBL
MKIVDHISNAKGTPLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HPNGLLEKIAYRKRPSTVATCAAIMNKYNVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDNSFIPTPDGHAYASELLQHVVDMNNGRYLHDYMEDAAKTDFCIGVAGY
PEKHYESPNLDTDFKYLKHKVDTGADFIVTQMFFDNKKYKALVDKCRANGINVPIIPGLK
PITSSKQLVSLPKIFHLDIPMELSEAIQSCKSEKDVKEVGIEWMIHQCQELKEMGAPVLH
FYTMGNPEPTKKIVQAVF
>A0A4P6V3Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseitalea porphyridii|TrEMBL
MNDTRIPASIEIAPKQALESADLPGLFPAGTRVYITDVGSDSSPVLVRAAARVHDLGYRP
VPHFASRRLTTRAALEDRIRAMTDEAGVTDVLVIGGGLERPAGEFTSTMEVLETGFFDKY
GVTDIGIAGHPEGSPDFSGQVALEALRLKKNFGERTGARMRIVTQFGFDGDKFATWAQGL
RAAGIDMPVHLGVAGPAKVTTLIKFAAMCGVGNSLSFFKRNTRSIATLATSHSPEGVVGP
IEAAWRANPTGNVRQIHVFPFGGIKKAAEWLAQRGSWDIKTSTYPHAEQGAQQ
>A0A5E4S4K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea communis|TrEMBL
MSGSLDNKTIMTQPSFSFEFFPPKTADGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQG
TLDTVIEIQREGVEAAPHLSCVGSTKENIRQILETYRANGIRHIVALRGDMPSGMGEIGE
FRYASELVEFIRAETGEWFHIEVAAYPEYHPQAKSPRLDLEHFANKVKAGANAAITQYFF
NADAYFRFVDDASRLGVAVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
EAIRAFGLDVVTALCERLLAGGAPGLHFYTLNAASATKAMWQRLGL
>A0A522ZQK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MSHASNLPVSFEFFPPKTPEGVHKLRAVRQALYAQKPEFCSVTYGAGGSTQGGTFAAVRE
ILGEGVDAACHLSCIGATRAGVRAQLAELRSMGVARLVALRGDLPSGYGAGGEFHHASDL
IAFIRAETGPQLRIHAACYPETHPQARTP
>A0A1M6YM84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius pacificus|TrEMBL
MKKPNVSFEFFPPKSLEASFRLWDTIHTLAPLGPRFVSVTYGAGGTTRELTREAVGTLHK
ATGLNVAAHLTCVDATREETLAIADGFHKAGVSEIVALRGDPPKGSNGFTPNPEGFANSC
ELIEALADTGKFTIRVGAYPEKHPEAADRQADIDWLKRKIDAGANEAITQFFFEAETFFR
FRDDCVKAGIDAPIIPGVLPIENWAGVRKFAQACGTAIPAWLDDTFDKAIRDDRQDLLAT
ALATELCSELIEGGAEDLHFYTLNRPELTRDVCHALGVTPKVELRDVA
>A0A1Y1T7Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zunongwangia atlantica 22II14-10F7|TrEMBL
MKVTEHIEKAKGKTLFSFEIVPPQKGKNIQELYDNIDPLMEFNPPFIDVTTSREEHIYIK
RDDGLLERKITRMRPGTVGICAAIKQKYDVDTIPHVLCGGFTKEETEYVLVDCHYLGIEN
VMALRGDAMKHQRYFEPTKGGHIYANELVGQIRDLSKGKYLNEVIDSENHPDFCIGVAGY
PEKHLESPSLETDLKKLKAKVDAGADYVVTQMFFNNQAYFEFVEKAKEMGINVPIIPGIK
PIAVKKHLQLLPHVFSIDLPQALIESVEACKNNKEVRQVGIEWAIEQTKELKAAGVPVLH
FYSMGKSSNIKQIAEAVF
>A0A6L8VH95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frigidibacter albus|TrEMBL
MTTPRISFEFFPPQSLDASFRLWETVQVLAPLKPSFVSVTYGAGGTTRKLTHEAVTTIGK
NYGLNVAAHLTCVDATRAETLEIAQSYADAGVTEIVALRGDAPKGQARFTPHPEGFADSV
ELIAALAETGRFTLRVGAYPEPHPEAANTAADVAWLKRKIDAGASSAVTQFFFEAETFLR
FRDACAAAGINAPIIPGILPIENWDGTRRFAARCGTQVPAWLDEAFGAAKRDGREALLST
AICTELCDTLLREGVEDLHFYTLNRPQLTRDVCHALGVVPEVSLEKVA
>A0A7C3RI06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyoglomus thermophilum|TrEMBL
MNFEEKLKSGKFIITAEVSPPRGVDVSSFVSKTLMLKDRVDAVNVTDFQNVGVRITSLVG
SYLLLKEGIEPIFQITARDRNRVAISGELLSAYTLGIKNVLVLTGDYTTTGISKSAKPVF
DLDAVNILKIAKMLESGEDFAGKKLNKSPNFFLGAVFNPNLTPLDIEILKMKKKILAGAE
FFQTQLVFDLSIMERVREKVGSGVKIIVGVTIFKSLEMIDYMINNVPGIKIPRYILEKFE
RKDNIKNIGIELCVDLCSKIKESKLVNGVHFLASKPSDIIEVMNILRW
>A0A2Z3N4P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus thermoleovorans|TrEMBL
MGLLDKLKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEEAAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTRRSVIVELDPPKQLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIVKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACGGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A7W6U2P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium esperanzae|TrEMBL
MALNNEVRGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWAPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKDETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGISIPIVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGLNEFHLYTMNRAPLVSAVLDNLGLSRRAPKSAGAAA
>A0A6L7GHD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allopontixanthobacter confluentis|TrEMBL
MTHSLDLAQEARTAHDNPLFASLPGDISASFEFFPPKSEKMEAMLWDAVQQLKPLGPDFV
SVTYGAGGSTRERTHNTVARIIAEAHIPAAAHLTCVDASKAEIREVAEQYWEAGVRHIVA
LRGDAGEPGAPFVPHPDGYASAAELVAGLKTIADFDISVAAYPETHPDAQCPDSDIDNLK
RKLDAGASRAISQFFFSPEVFFRFQDKLAAKGIDAPVLPGILPVTNVAQARKFASACGAA
IPPWMDGLFDGLDARPAARQLVAATVAAELCRRLYAGGVRQFHFYTLNRADLAYAICHLL
GMRPAGENQ
>A0A3R7A7I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Syntrophoarchaeum sp. WYZ-LMO15|TrEMBL
MRNIKEGKFVFTGELEPEKTTDLTELVESAKKLLGHCVACNVTDNPQSMAYMSSLVASYV
VQRDAGMECVYQLRCSDRNSIALTSDLLGAGALGIKNVLALTGDHTTLGDYPGAKPVFDL
DSGQLVYLIRKMVDEGVDLYGRPIHNPPKFHVGVAGNPNADPLESEILKLKRKIDAGAEF
IQTQVIFDIEVAKTFLKEMERFKVPVLIGIFPLKNYGTADYFDKYIPGVHVPKDLLSEMK
KASEISDKEKRNERYDEINLEYYGDFVHEIAHTTSAAGIHVMAVAYERITPALIERAKI
>A0A7L9LPD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella suis bv. 1|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATCEDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A7K7EUU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sylvia atricapilla|TrEMBL
MVNETQQTGSGSSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDVCVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVVEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7D7X538|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulicella sp. 5B5|TrEMBL
MESAVDKLFAGETVLCDGAMGTMLYSCGVFINRCYDELNVTQPEMVRSVHELYLQAGAQV
IETNTFGANAFRLEGFGLRDRVAEFNRAGAAIARQCVQAIAEKQGSVAFVAGAIGSLGLR
LAPAGKTTLSEARAAFAEQIRALAEGGVDLLIAETMMSVDEAEQAVLAARDVAPQLKIAV
LMTVGEEGNCLDGSSPEIAAQRLTAVGADAIGCNCSVGPATVLSVIEKMRAATGLPLVAM
PNAGMPRQVEGRNIYLTSPEYMASFARKFVRAGASWVGGCCGTTPEHIRAMRGALRAMDA
QESGESSLKLRAVVASEAEAGIEPLALAERSGIGRRIANGEFVTMVEIVPPKGFDCSKEL
AGATLLAKHGVHAINVPDSPRASARMSAQSLCVQIQQQVGIETILHYTCRDRNVLSIQSD
LLGAASIGVKNILCLTGDPPKMGSYPDATAVFDVDAIGLVNIVGGLNHGLDIGRNSIGGS
TGFTISVAANPGVPDIDHEIRRFEHKVAAGAEFCITQPVFDLRLLEQFLRRIEGFRIPVV
AGIWPLTSLRNAEVLKNELRVSMPDVILQRMADAPNREAALAEGLTIAREMLASVRGEVQ
GVQVSAPFGKYTAAVEVLGVLGEEA
>A0A4Q2WXN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium|TrEMBL
MPISFEFFPPKTDEQRATLDAALPRLKAREPEYVSCTFGAGGSTLRYTPETIRRLREQHA
LDAAPHLSCMGGTREEIRALLEDYRACGVRRLVALRGDLPSGMASHGDFRYASELVEFIR
AEHGDRFHVEVACYPEVHPQSDDAHADLRHFKAKVDAGADGAITQYFYNADAYFRFVEAA
RGAGIEIPIVPGIMPIANFTQLKRFSDLCGAEIPRWMAKRIQAYGDDVDAIREFAADVVA
DLCRRLVAGGAPGLHFYTLNRARPTLAVLDRL
>A0A3D9RT37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibacter oceani|TrEMBL
MKVTDHIKQAKGKTLFSFEIVPPQKGQNIQDLYNNVDPLMEFNPPFIDVTTSREEYVYIK
KDNGLLEQKMTRMRPGTVGICAALKYKYDVDAIPHVLCGGFTKEETEYVLVDCHYLGLDN
IMALRGDAMKHEPYFVPTKDGNVYASDLVAQIKELNQGKYLHNIIETTNKSDFCIGVAGY
PEKHLEAPSMDTDLRRLKEKVDAGADYVVTQMFFDNQKYFDFVEKARNIGITVPIIPGIK
PIAVKRHQQILPQIFRLDLPEELIAAIEGCKDNKQVRQVGIEWAIQQSKELIAKGAPVVH
FYSMGKSDNIKAIAKEVF
>H0EVR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glarea lozoyensis (strain ATCC 74030 / MF5533)|TrEMBL
MHEVRGMGMSGEMIVIMHVSEMLAEAKQTGQPKYSFEFFPPKTAQGVQNLYDRMDRMHGL
GPSFIDITWGAGGRQAQLTCEMVSVAQSQYGLETCMHLTCTDMGKEKVDDALKSAYKAGC
TNILALRGDPPREKEKWTATEGGFHYAKDLVKYIKQSYANHFDIGVAGYPEGCDDQDDPE
ALLDHLKEKVDAGATFIVTQMFYDVDNFLNWVAKVRARGVTIPIIPGIMPINTYASFVRR
CNHMNASIPPEWSEKLEAVKNDDSAVRSIGTGLVAEMCRKILDSGEIHHLHFYTMNLAQA
TRMLLDELNLTPSTERPLKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFP
NGRWGDSRSPAFGELDAYGIGLRGTNEQNRKLWGEPKSISDIANIFVNYLEQSVDSLPWS
EAPITSEADVIKQDLIALNRRGLFTINSQPAVDGVKSSHPVYGWGPSNGYVYQKAYIELL
VSPDLIDELITRVEKDPELTYYSVNKAGDLKSNSPGEGPNAVTWGVFPGKEIVQPTIVET
ISFLAWKDEAYRLGMDWAHCYDAGSPSRQLIEKMMNEWHLVNIVHNDFHQSHGLFPLFDG
LTVQNINKPFEATTTNGVNGTAPKSNEHLPLTNGTGNALVAA
>A0A1Y5GS99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassotalea sp. 42_200_T64|TrEMBL
MNTKARQLDLLNRTIRDIDNDLNVSFEFFPPNSPEMENTLWSSIERLAPLNPSFVSVTYG
AGSGTRDRTHGVIKRIQKDTGLIAAPHLTCIDAGREELIDIAKDYWASGVRHIVALRGDL
PNNTSKPDMYANDLVELLKGVADFDISVAAYPETHPEAPNAQFDLVNLKRKVDAGANRAI
SQFFFDMDSFLRFRDRCVAVGIDVEIVPGILPVSNFGMLKRFADMTNVHVPDWMGKMYEG
LDDDPTTRNMVGANIAMEQVKILRSEGVNDFHFYTLNRSELTYAICHTLGVRP
>A0A254PTQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter campilacus|TrEMBL
MELSVEFFPPKTPEGEKKLHLVRERFSQTLNPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVREMLKQYQSLGIKRIVALRGDLPSGMGQYGEFHHANELVEFIR
AETGDWFHIDVAAYPECHPQAKSPASDVHFFVQKMKAGANSAVTQYFYNTDAYFRFVDEA
YNLGVTEPIIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDIASIRAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLDLTK
>A0A510VAI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas xylanilytica|TrEMBL
MSNVPQAMCPRTAPVPDHPTGRAVSAAAVEPRTPGLHVSPSRRAVAANDRPTISFELFPP
RNPDAAPRLWNTIQQLETVKPDFVSVTYGASGKTRVTTRALVRRLLRETSLNPIAHLTCV
GTSREEITTIVGEFLDEGLRSFLALRGDPPTDQSDWAAHPDGLQTASELVELLRDIEAKR
CADSPSQAVRARVRPLSVAVAAFPRGNHATGGTRAQDVASLLAKQEAGADFAITQVFFDA
DDYLGIVAEAREAGVTIPIIPGIIPTTDPARLLRVQELTGVPVPHDLLDLLGSADDELDR
HHRGIRASVDLVNGVLDGGAPGVHLYTFNQHHAALDLLEGAHLDGGARTAPDLASWPQDT
APARSTRD
>A0A0R1NUS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus kisonensis DSM 19906 = JCM 15041|TrEMBL
MFKQKTVFSLEVFPPKKTSPTAAILPTLEQLQSINPDFISVTLGAGGTDHYNGTVSVADL
IQNQLHIPAVAHVPGLYQTKQQVLDLLDKLSSINIENVLALRGDRIPDKQPAGDFNHANE
LVAFIKQNRPNFSIASACYPNCHTEAVDFVDDIGNLKRKVDAGVDHLITQLFFDNQAFYD
FKEKTEIAGINVPIEAGIMPCTNRNQIARITQISGVPLPKKFRAIMDRYQDNKEAMRDAG
IAFAVDQIIDLVSQGVDGIHLYSMNHAGIARQIWEETHSVIEA
>A0A7W5VIK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea dietziae|TrEMBL
MALGRPSVLPDRVPTVRDLLASGGRSFSFEFFPPKNEEGERQLWRSIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERIAHETTLTPVAHFTAVNHSIRELRHLVGRFADAGVRNILAVR
GDPPGDPNGEWVKHPEGVLYAEDLVRLIRQAGDFCVGVAAFPYKHPRSPSIEADTDYFVR
KCRAGADYAITQMFFQADDYLRLRDRVAAQGCETPIIPCIMPVTRMSTIARSEQLSGAPF
PPDVAARFEAVADDPAAVRRLGIDHGAELCQRLLDEGAPGIHFITFNRSSATREVFQLLH
PAALTV
>C2WC34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus Rock3-44|TrEMBL
MKILDLLSKGIIIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADIIQTN
TYGANEAKLRTYGLENQVVQINRAAVKLAKAAITDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALIEENVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQLALHEAGTTQNGN
DVNEILEQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPAHIEAMKRAIANVTPVTEKQIVQRQQVVP
MQTKRISTHVTLAEKAKKQTTVIVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNEGRSILGKSIGSATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIGGVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMDGHDTQESAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITENLVNYVK
EKQEVKEGVN
>A0A7G6SIF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium sp. 628|TrEMBL
MTKIAASIEVAARQAIESQDLPGLFPEGTRVYITDMGTDGVDTLTAAAKRIHDLGYKPVP
HIASRRLGTRAALETRIRRAAEEAGVTDVLVIGGGLERQAGDFSSTMEVLETGFFDKYGI
TEMGVAGHPEGSPEFSEAVALEALRLKKNFGERTGARLRVVTQFGFDADRFIRYSESLRE
HGVDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNALSLTALATSHSPEGVVGPIE
QHVVNNPASAIKQIHIFPFGGLKKSSEWLVDRGSWNVASAPFASAVNN
>A0A4R0EQR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter terrae|TrEMBL
MSQLSTCFTQNQFCVLVEYLCSMKEILPVKTEFAGFPALMTLADRVHSDDDLAPLLAAQA
YPKSVKKVLHFAGKGRDIADFEHFLNEAQAVGLQNLLLLTGDKLKSHQYGQDDITKRTRY
LESVNAVMAAKQRGGFCIGVAFNPFKYAEAERDAQYFKLYKKMKAGADYIITQLGYDLSA
LKEVKAFLTQHGYPQKLLACVMPLTLARANFMVKHQVAGIVITSHMLNVLREEKESGLTD
RVYLRCALQILICKHLGLAGIHLSACHKPEEQMLLESYIEEYRHLDLDALELLWNTLWQV
KTGQEFYPELSYYSRPASATQILKYQQLHLMHDALFESKVAKGVGRFIFQSRFWNGALAA
KALLKTEFVSKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDREC
IHSVKARLAKAVNQTKILKDNLIPTVPIEVRGSSSWKNWYLKKAV
>A0A0G4NKR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium longisporum|TrEMBL
MTRLGDLTSHGPLENLVRPSSVLNTSPTIQSRSASPASPAGGLGICTTPRTLPLTWTAHV
CLRGCSSAAVSSAVGNAADXPSGAFKTIPIIPGLMPIQSYQMIKRTTKLSHAKIPDALMA
RLDAVKGDDEKVKEVGVDIVSELVDQIRAVKSKRTTGPQGFHFYTLNLEKAVSFILERTN
LIPDKEQEDEEAVIDDATTPPVVPTVQINGLHPGSHHRPGRRQSSIGSDPHNRTVTQKLV
RWLEMPADQASADMPSNTPTTKTYYVTPRNISPWSSKGTSITHVCGLKDQIERIERGQAI
TVTFDQGLTKDTDGIPFKDIIYDRMTETIGLAQPDLNTIFVEGQRYPLEIVDIFAAGAQT
PLERLRDHNKKFGLALDESEMEYLVEVFKRQGRPPHDVELFMFAQVNSEHCRHKQFNASW
TIDGEQMADSLFGMIRNTHKTTPDYTVSAYXWADEA
>A0A4P8XZR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus bovis|TrEMBL
MKVSELYKDNKKTLSFEIVPPEKNSELSSIDETLDILCELNPDFISVTFGAGGSENCNST
IEVARKIKEKYNIEPVVHLTCLNYSKDEIDLIARQLQQSGVQNILALRGDKVPNVQAKND
FKYASDLIAYMKSKYDFCLLGACYPEGHPESESFVDDIKHLKEKVNSGAEVLLSQLFFDN
NYFYDFQEKCKVADIDVPVIAGIMPAISKSQLEKMVSLCGVTIPPQLKRIVHKFSSNKDA
LFDAGMSYGISQIIDLLTSDVDGIHIYTMNNPMVAKRISTEIHNFI
>A0A412XBX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF14-35|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFNTPSVAHLTCVGRSHADIVAKIDEYRSAGVENILALRGDLPTGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A4U8QC11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robinsoniella peoriensis|TrEMBL
MKSVIDIMKERTSFSFEVFPPKAEQPMEPLLNTLDELYQFDPDFISCTYGAGGSNAGRNV
EICKAIADSGHRAVTHFTCIGNTKEKMKAELQAYLDNGVNHILALRGDLPAGWEGTRGDF
NYANELVAFIRAEFGDQFTIAMAGDPEKHIQCPTFEEDIAHLKMKQDAGADYIMTQLCFD
IEQFKRWVDQIRNAGITLPIDVGVMPVLNKDATIRMALSMNGCSIPRDLAEVISKYYNDP
EGFKEAGIDYTVHQLYQFIGEGVEGIHLYALNKSAAVSEILTRSGLRTKAE
>A0A5J6INI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cinereoruber|TrEMBL
MALGTASVRSDRARTVRDILASGGTSYSFEFYAPRTEKGEQSLWRAMRRVEAVGPSFVSV
TYGAGGTTRGGTVKATQKIASDSTLTPVAHLTAVGQSVAELRNILGQYADAGIRNMLALR
GDPPGDPLGEWIEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVVKAGCETPIIPEVMPVVNVKTLDRLPQLSNAAF
PARVKERILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A4P8XUK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus bovis|TrEMBL
MKLSNLYTKAKEEGKTVLSFEVFPPKKTSGIETVYKALDELAKMNPAYISVTYGAGGTEA
NNTAIIAEKVKSLGVEPLAHLTCVNNDRVSVEKELDEFKSKGIENILALRGDIVPGIEPK
KDFLHASDLCSYIKARGDFELAGACYPEVHMEAKDMVEDIKNLKHKVECGAEHLISQLFF
DNEVFYKFQDMARCAGIDVPIAAGIMPVTNTKQIQRMVSMCGASLPANFSRIMQKYENNP
EALRDAGIAYAIQQIIDLIANGVDGIHLYTMNNPYVAGKITEAIGSML
>R5H5U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira sp. CAG:484|TrEMBL
MCYNSAMKLNEIYGKEDGLKISFEVFPPKGGEVEYPELLKELECLEKYKPALVSLTWGAS
GNNNNSFELIKILNEKYNLMPHFTCVCNNFTNVEQHISNIETLGIENILALRGDIPKNIN
GYCSDFRYANELVRFIKSKSNLCVGVAGYPEGHIEALDMEFDIDNLKKKIDEGAEAVYTQ
LFFDNERFFRYIELVRKAGINIPVIPGIMPVISMKQILRMVSMAKITIPAALMQKFEQYE
NSPLEMRKFGVDFASLQCSELIASGVKGLHFFTLNKAASTSQILDNIL
>A0A520SW29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiritimatiellaceae bacterium|TrEMBL
MARTQPRIRPMSLLEKIQHQPLIGDGAMGTMLYNQGIFINTCYEQLCLTQPDLIRNLHQQ
YVNAGADLIETNTFGANRIKLQAHGLADQLEAINRAAVQLAHQSKQPNTHILASIGPLLT
SDQLFTDRHTHELEQLFHEQMSILADEPIDAFQLETFTHVDEAELAATIAKTYNLPVFVS
VTVGKDGETRRGETIEQIIRQLDASPAVDALGINCGLGPAAAFSIAERALPLTQKPFTVS
ANAGLPQEVDGRLIYMSTPEYFSEYAKRLIELGVRLVGGCCGTTPEHISTMAQQIKSLTG
VKQHIQITQHQQQETPPVEAISTAEKCRFGAKLKAGEKVTSIEITPPRSIDLQPMLDKCR
QCHDAGIDAINIPDGPRASARISPMVAALAIEREIGIETVLHYCCRDRNLIGMQSDLLGG
YAGGLRNYLIVTGDPPKLGDYPDSTAVFDVDAVGLTQVVNNLNHGIDVGGNPVNPPTGIL
IGVGANPCAVEPERELNHYLNKINAGAEYAITQPIFDPEALLRFLDAADARGATIPVVAG
VWPLVSYRNTQFLKNEVPGVEVPDTLLERMSHAKTKEEGRAFGIQIAREIRDKIADRVAG
FQVSAPFGIVDLALQVLD
>A0A0Q4FDS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agreia sp. Leaf210|TrEMBL
MEYGPCGGVGFDGSCEVGDFRCVFLDDPLVTWRVGAPAESEAVRRSSGAAEMMALMTTRP
IVVADFPAKAMDAESLTECAALLAGPVDAALAGDAGTARVQFSPSYRASLIRAAGLQVWT
GLNCRDRNRVAIEGELAGLAHIGVAGVHCVTGDHTLLGSRPDAAPVFDLDSSQLAALARA
AGHLVSVGESPTTPPVELRAARLLEKTRAGADVCFVNHCGGVDAVGRFVRESHDLGVTAA
FIPCVPMVTDHGSARLLQSFPSLVLPDRYLERIVSAEDPREEGIRAAVALSLELLEIEGV
AGVNLSGGAGAGHEAEFAIALAETAQRLAL
>B7JMX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus (strain AH820)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKAMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFYGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>Q8NNM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)|TrEMBL
MSLTNIPASSQWAISDVLKRPSPGRVPFSVEFMPPRDDAAEERLYRAAEVFHDLGASFVS
VTYGAGGSTRERTSRIARRLAKQPLTTLVHLTLVNHTREEMKAILREYLELGLTNLLALR
GDPPGDPLGDWVSTDGGLNYASELIDLIKSTPEFREFDLGIASFPEGHFRAKTLEEDTKY
TLAKLRGGAEYSITQMFFDVEDYLRLRDRLVAADPIHGAKPIIPGIMPITSLRSVRRQVE
LSGAQLPSQLEESLVRAANGNEEANKDEIRKVGIEYSTNMAERLIAEGAEDLHFMTLNFT
RATQEVLYNLGMAPAWGAEHGQDAVR
>A0A850KMK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MAQRYNPHGSHSLFEEVVSDVNVSFEFFPPKTPKMEETLWNSIKTLEELNPKFVSVTYGA
GGSTRERTHNTVKRIVDETNLAPAAHLTCVGATRDEVDDVVRDYYAAGVRSIVALRGDPP
EGASSYEAHPGGYANAAALVEGIRKIADFDISVAAYPEKHPDSATLAADLDNLKRKVDAG
ANRAITQFFFEPDQYFRFLDHCQSYGIDVPILPGILPVTNYATLKNFAATAGASVPKWLG
DLFDGLDDRPQTRQLVAATVAGEMVRRLYAGGVRDFHFYTLNRAELTYAICHMLGIRAGQ
EG
>A0A7T8FH02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLVEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3D8K678|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trinickia dinghuensis|TrEMBL
MNPIEISFEFFPPKTPDGVEKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMAK
DGIEAAPHLSCIGSSKESLRAILERYRSNGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRAEHGDWFRIEVAAYPEYHPQARSPRHDLENFARKVKAGADAAITQYFYNADAYLRFVD
EARKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDREAIRAFGLDV
VTQLCERLVKEGAPGLHFYTLNAATATKAICERLA
>A0A3Q0L3M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio vulnificus (strain CMCP6)|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSTPQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAQTGLVAAPHLTCIDASREELINIANDYWANGIKNIVALRGD
IPPGGGAPDMYASDLVTLLKSLHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDDDPVTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKKA
>A0A350QFF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Azambacteria bacterium|TrEMBL
MAFANARYLDAINRNLHDVQGKVNVSFEFFPPKTPQMEQTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASKQQLIDIARDYWQNGIRHIVALRGD
LPSDSAAIPELYAADLVEILRSVADFDISVAAYPEVHPQAPNAQFDLLNLKRKVEAGASR
AITQFFFDIEKFLRYRDRCAAIGIDVDIIPGILPVTNFQQLQKFAGLTNVAIPHWMNKAY
QGLESDPTTRNLVGANIAMEMVKVLSQEGVDQFHFYTLNRSELSYAICHLLGARPML
>A0A537VN10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MACVMTTVEDRADPIEAIADFTAGFSLETTRPSADDVAALAGIVPAGASVYVTAVPGRPA
RETIETAAQLRTAGFEPVPHLAVRGFASALELDDFLARASGQAGVTRVLVIAGDHDEPAG
DFRSAIEVIDGGALQRHGITGIAIAAYPDGHPRISQQDLDRSLADKIQSAEATGLAVHIV
TQFGFDAQAILQWIGRLREFGVEHPVRIGLAGPTSLATLLRYAKHCGVRASAQGLARQAG
LLRQLFAMSAPDALVRALAQARADKHLGEIAPHFFSFGGLLRTARWAAAVAQRRIALEAG
EGFRVEPPPTEG
>A0A354X967|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium|TrEMBL
MKVIDLIQEISKATFSFELLPPLKGNSIRQVFAVIDRLKEFDPKYINITTHHSESMYKED
AEGVYRKISVRKRPGSVAIAAAIQNKYGIKAIPHIISQGFSKEETEYALIDLSFLGVTDL
LLLRGDTKNLDALQRNLDSHPHASGLQEQVNDFNRGVSFDGSSLTPPEIPFSYGMACYPE
KHEESPNMESELFYTKMKVQNGADYLVTQMFFDNRKYFEFVDRCRAEGITVPIVPGIKPI
HLKNQLTVLPRIFRTDLPEELAKALRTCQSDDEAKQVGVEW
>A0A232M5Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elaphomyces granulatus|TrEMBL
MEKITDKIAGLPQDAHYFSLEFFPPKTQMGSANLQARLERMVHSLRPLFVTVTWGAGGTT
AAKSLELAEICQRQLQLTTCLHLTCTNMNRRLIDEALEEAKALGIRNILALRGDPPRSEE
YNIDGSDDSNKDFTWAVDLVRYIRRVHGDYFCLGVAAYPEGHPGDSFHEHQDPAYDLPYL
VEKTKAGADFIMTQLTYDLEAYKKFEAALRNHESGVFKTIPIIPGLMPIQSYNILTRVTK
LCHTKIPPPILSRIEQVKANDEAVKKVGVDIVAEIVNGIKGIPSPGPRGFHFYTLNLEKA
VSFVLECCDLIPPLTEESDDEFDTEVAITMSLQDSVVTGDQIRSLSRRRASSINSQPHNR
LIVDKLQISAKGSAKSSITHEAPALSAGMPAMNPPPRSTTLQISEGLGSLGREATWDDYP
NGRWGDSRSPAFGEIDGYGPSLHVGAPVARTLWGFPTSQADISSIFRRLVSGQLHMVPWS
EGGAAEESGGLNPETATIRPELLRIIDSRNWWTLASQPAVNGVRNDDPVFGWGPPGEGFV
FQKPFVEFFCPGTEYQSYLKPLLQRYGHAEFAWFAMNAAGDFESSLTTDTTLLDSLNGTT
SPSDSGIDDAGMNSSTVNCVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYP
RGSATELFLDSTKNDVWLVCVIGQRFGAGTEPGSAEEEEEMKLLWGVIAGEQ
>A0A0C2AWZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. AcH 505|TrEMBL
MAFGTPSTWTTHAPTVRELLASGPTYSFEFWAPRTPKGERNLWNALRRIESVAPSFVSVT
YGAGGSTRDGTVKATQQIAADTTLTPVAHLTAVGQSVAELRNMIGQYADAGIRNILAVRG
DPPGDPMGEWVEHPQGMRYAAELVRLIKESGDFCVGVAAFPEMHPRSADWESDTRHFVDK
CRAGADYAITQMFFDPEGYLRLRDRVAAAGCATPIIPEIMPVTSVGQLERLRQLSTAVFP
AELKERILSVKDDPAAVRSIGIGFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HEQS
>A0A2D9XRV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTTFSFEYFPAKTDKGNLRLLDTARTLAKKKPSFMTVTYGAGGSTKDGTLDTVTCLQRET
GVPMAAHVTFINTEIPQLKKFADELWDKGIKRLVALRGDLPDDLSWPLDLEGNYFQYTSE
FVAALKSWHNFDISVGAYPEKHPDAPSLAADVRALRLKCVAGADRAITQFFFDNSIYYKF
LEECEKAHIKTPVVPGLLPIHDFQSMLSFAEKCRATVPDDIRKKFEALKHNPEGAKDLAQ
DLLCAQVEDLASQGCPHVHFYTLNKSDLVDMACQSINAAV
>A0A348USY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacter sp|TrEMBL
MKTESRLEKVLASGQLAVTSEVGPPRGCNIDVIKEKANMIKDYVDSINITDNQTAMVRMS
SIAGGIVIKQMGLDPIIQMVSRDRNRLAMQSDILGAYALGCNTMLCLSGDHPQFGDHPMA
KPVYDIDSINMIKMVKDMRDEAKFQGGADITDPPKMFIGAAANPFADPFELRVMRLAKKV
AAGVDFIQTQCIFNTAKFETWMKQVVDRGLHEKVAILAGITPMKSLGMAKYMKSKVPGMD
IPDEVIDRLAGVDKDKQAQEGIKMAIEQMQRLKECKGVKGFHIMAIEWEEKVPELVKGAG
LYPRPQV
>A0A509DWH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassocella blandensis|TrEMBL
MTDQEPLRLSFEFFPPKTGQGREKLKVVREELQALNPDFFTVTYGAGGSTRDNTKGVVRA
MREEGKSVAPHLSFGGDEEESIIELINEYKEMGVDRIVALRGDMPSGVGGALQMVHANEL
VSFIKKHFANDFHLEVAAYPEIHPEAISYETDINHLKGKFDAGADSGLTQYFFNPDAYFY
FIDQCDALGITKPIYPGIMPITNYKNLARFSDACGADIPRWIRKRLEAFRDDHESIVNFG
IDLISELCETLLDNGAPGLHFYTMNQTDPTATIVKNLGLEQRNS
>A0A1B2LXD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter larvae|TrEMBL
MSLLATCFAQQQFCVLIEHLCSQKKQFAVSRHFAGFPAVMTLADRVQHDDDPAPLSCSTN
YPAEVEKVLHYSGKDRDIVDLQQFLQEAEQAGQQNILFLTGDKLKQHHSGHEGYPRTRYL
ESVNAIMAAKQYGGFYIGAAVNPFKYTQAEQDAQYYKLHKKIKAGADFFITQLGFDLSAL
KKLQIFMQQNYPKHALLTCIMPLTAARAHFMHREKVAGIVISSYILDFLAQEKALGYSER
VYMRCALQILICKAWGLAGVHLSACHTAKEQQILAHYLDCYRSMPLSECLALWYALWQIP
NDRLLQPKVPCYARPASSTEIIQYQKFKLIHRVLFQTKFSQGIGYFIFKRKFWDRTLANK
ILLKVEHMTKHHAVGCESCGQCRLEETLYICPETCPKGLANGPCGGTYLDRCEFGDRECI
HSRKARLAKAILAEDILSEKIIATVPKKIRGSSSWKNWYRIEY
>A0A816T2K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica napus|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRANGIQNVLALRGDPPHGHDK
FVKVEGGFGCALDLVNHVRGKYGDYFGITVAGYPEAHPDVIGENGLASDEAYQSDLEYLK
RKVDAGADLIVTQLFYDTDVFLKFVNDCRKIGIKCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEVMAALEPIQDNEEAVKAYGIHLGTEMCRKILAHGTKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALTDHQFSRPRARDKKLQQEWVVPLKSVEDIQERFKELCLGNLKSSPWSELDGLQPE
TKIINEQLVKLNCKGFLTINSQPSVNAERSDSSTVGWGGPGGYVYQKAYLEFFCSKEKLD
AIVEKCKALPSITYIAVNKGDNWVSNTAQSDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFETWSRSWANLYPEAADPSRNLLEEVKNSYYLVSLVENDYINGDIFSVFVDL
>A0A2E6JMY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MDVASLYRNAPGGLPFSLEILPPNRGLGLNNIHDFFNNLHEWLPAFVSVTYHQAHKIDII
DDNGQMEQIWNRKKPGTLGVCAMLKFQYGLNVIPHVICGGFSKFESEDFLVDLDYLGLKH
ILALRGDPNKTETQFNPHPQGYAYANELVEQIVDMNAGKYVEDVKEARPTDFQIGVAGYP
EVHAEAMNLHDDVTNLKRKITSGASFVITQMFFDNTCFFQFDKMCREMDIHVPLIPGIKV
ITSKRQLEVLPEIFGTKLPKKLVDDVMACETDEEVCQVGIAHAVNQTKELLEYGVVGVHF
FTMNNSQVFNQVLQQFQE
>R9M951|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillibacter sp. 1-3|TrEMBL
MTDIRTYLKAGEPLLFDGAMGTWFAALPGRTGERCELGSLNCPEEIEAIHRAYLEAGCRA
VKTNTFTVSLDLARGDGETAERIVEASCRLAQACAEPYGAYVFADIGPAPESRELSRAEN
YCRQADLFLDRGVRHFLLETLPSDHGLRQLAQHLKARCPEAYLITSFAVSFDGATREGDF
GQTLLRRAAALEEIDAVGFNCVSGPHHLLEYIRGLDTGGVTLSVMPNAGYPSVLGRRTVF
QGTPDYFGRKLAEIVQAGASIVGGCCGTSPAHIAEAAKALAAPRRITVCVRSGGAPEPRP
AASANTLAEKLDAGRRVIAVELDPPVDDDISFFLEGVRKLRDAGADAVTIADCPIGRPRA
DSSLLACKIKRELGVEPLPHMTCRDRNRNAAKALLLGLSMEEVHNVLLVTGDPIPSEDRD
EVKSVFNFNSRRLAAYVSGLNETVLRTPFRIFGALNVNAKNFDQQLRIALEKEENGVTGF
LTQPVLSREALENLKTARQTLRGKILGGIYPVVSHKNACFLNNEIAGMHISEEIVSLYEG
KGREEAEDLATAVSARIAGEIASCTDGLYLMTPFKRVALMARILREIQGAHRV
>A0A534LLG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MAEAVGVRAVRSGGHLERMLASGAFAVTAEIAPPASADPTDIREMVSRYRGAVDACNVTD
CTRARVRLSSLAAATIAMQEGIEPVMQIVARDRNRIALARDLLRMIRTLELCDRYGW
>A0A2R6H228|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QS_1_68_17|TrEMBL
MALRSRSQSTQEGVRELLDDPRFELLPFESFDEQLDYLPDGAQIAITSSPQKGIMETVER
SEQVQREGYRAVPHIAARAVRDEDQLDEIAGRLEDAGVTDVFVPGGDNEDPGAFESSYQL
LVALAELGYEFEEVGITGYPEGHYFIDEETLWEHLEKKQPHATYITTQLCYNPDAIVDWI
ETVRERGTDLPVEVGLPGVMKYQRLMSISRKVGVGDSIEFLRKTTGLASFIKTLIGSRGK
YTPDKLVDGLAPYVDDPEYGIRGVHIYTFNQSGDTEEWRQERLQ
>A0A5R8MLJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas urmiana|TrEMBL
MKFDDEPVPGYSLPILPDHVSPGRLERVLRAGKFAITSEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYATILQISCRDRNRIAIQGEILGGAAMGAC
NLLCLTGDGVQAGDHPQAKPVFDLDSMSLLEIARGMRDDHRFQSGRRIETPPRIFLGAAE
NPFVPPLDWRPHRLAKKVAAGAQFIQTQYCFDIERLRDFMLKVNDLGLLEGPDRVFILPG
IGPLASARSARWIRANVPGVHIPDSVIARLEGAENQKEEGKQLCMDLLHQIREIPGVSGA
HIMAYRQEHTVAEIIEATGVLDGRVPWYPGRDDPKELNPESSEALLS
>A0A0S8ITK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium SM23_73_3|TrEMBL
MFGTFLERLKKGTMLCDGAMGTLLYMRGVSYERSFDEQNISNPKIVQNVHRDYIKAGAEI
IETNTFGANGVRLKNFGLEDKVGEINIKGAKIAREAREIEGRDVFVAGSIGPVGKPLAPL
GELSEKEALEVFQKQAEALLEGGVDLFIVETFSDLLEIKQAVLAIRNICQLPIIASMTFD
EDGKTFLGYSPEEVADKLSNLGVEIIGANCSVGPQKMLDVVGHLRKATNRMISVQPNAGV
PRYVDGRFIYLSSPEYFAQYAKEYIKSGANIIGGCCGTTPEYIKALSKMLEDIKTGTAPE
EKTYITVEERIKEEEPTEWEEEKISEFARKLGKEFVVSVEVDPPKGINTEKILKNVEKLK
QIGVNAINIADSPMARVRMSCVSLAYLIKQKIGIETILHLTCRDRNLMGLQSDLLGVHAL
GIHNILAVTGDPPVLGDYPQATAVYDVDSIGLVKIINKLNQGTDWAGNSIGSPTFFCVGV
AVNPTADDLKKEIDRFEKKVEAGADFAFTQPLYDLKILKQFLQEVSHVKIPLFLGVLPLR
SYKHTEFLHYEVPGINIPEKIRERMKRAKDRSYQVGTSVAKEMMEQAKGMVDGVYLMPSF
GRFEMISEVLEGFIPSRTTIFNK
>A0A662TXM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MKLAELFESGKFVVTAELGPPKGVDTNKMLQNADLLKGRVDAVNITDQQSSVMRLGSLAS
AHLVKQHGLEPIYQLTCRDRNRIALQSDLLSASVLGIENILCITGDYVSLGDHPEAKPVF
DLDSVSLLRAAKMLKNGYDMAGNKLLGAPSFCLGAVVNPTAEPLELQVLKLEKKVVAGAE
FIQTQAVYDPERFKEFVKQVKHLKIPIMVGIVPLRSASMARFMNKHVAGIHVPEELIERM
EKTRDKTGTSIEICVELIKEMKPFCQGVHIMAIGWEKIVPKILDACGL
>A0A3S1JWD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.015.02.1.1|TrEMBL
MTALQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A1M6KT59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidibacter formicigenes DSM 15518|TrEMBL
MSLLRKALKNGEFGVTAEMAPPKGIDFSHLIECAKAIKGRVHGVNVTDFQSAVMRTTSLA
TCKILKDHGLEPVLQMTGRDRNRIAIQGELLSAGLFEIKNMLALTGDHTVVGDHPGAKPV
YDLDSVGILQTAATLMDGKDMVGNELKGKPDFFLGACVTPRYAPLEVQILKMEKKINAGA
KFFQTQAVYDLDTMREFREKTKHLDCKVLAGIIPLKNVGMARFMNANVPGIYVPEDVIQR
IKDSANNVEIPNGATEKEVKKLKAYARVQEGIKIAGEFIKQLREENLCDGVHIMAIGAEE
NIPAILDAAGL
>E1LQW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis SK597|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSSNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A066YXT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora cheerisanensis KCTC 2395|TrEMBL
MRDLLAAGDRSFSFEFMPPRNEEGERKLWDAIRRVEALDPNFVCMTYGAGGSSRGRTVNL
VGRIATETTLTPVAHLTAVDHSVAELRNIIGQYADEGVRNVLAVRGDPPGDPMGEWVRHP
EGVSYAYELVELIKSIGDFCVGVAAFPQMHPRSTEWDEDIRHFVAKCRAGADYAITQMFF
EVEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQLVRFPQLSGSDFPPEFRRRLEAAADNP
AELRAVGLEHATAMAERLLAEGAPGLHFITLNHSTSTLEIYQNLGLHKH
>A0A1H5VPA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus boritolerans DSM 17298 = JCM 18970|TrEMBL
MKITEHLKNATSTLFSFEVLPPLKGQSLKELLEGIAPLMEFKPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMSRFQVDAVPHILCGGFSKEETENALIDLNFIGVDNV
LALRGDAPKSEGRFIPEPNGHTYASELVDQIVRMNHGHYLHEETENSFHTDFCVGVSGYP
EKHFEAPSMKFDLKYLKEKIDKGAEYIVTQMFFDNQKFFDFVKRVREVGIDVPIIPGIKP
ITTLSQITMLPRTFFLDFPDDLMDELEKCNTNADVKNVGIEWAIQQSKELVAAGVPSLHF
YTMSKAEATYKIAKEVF
>A0A2E3IQE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geminicoccus sp|TrEMBL
MTDTKAAVMKLFGDFTVETTPNSAAKIPDYNARLRTDTPIYVTFLPGSDVYETVTLAKRL
RAEGFSPIPHIAARSIQSEDMLRDILDRYVGEAGVEHLLTIAGGVDNPLGPYDSSMAVLE
SGLIDKAGIRRVSVAGHPEGSPDITDELIKDALAWKNGFAERTGAELDIVTQFAFEAEPI
IAWDKRINAEGNRLPIRIGLPGLATIKTLLGFSRAAGVGNSIKFLVKRAADVTKLMSINA
PDKQVIDLARYAAEDSKAGISGVHMYAIGGLKRTSAWSYALRDGLFEVTGKDQLKVSVDL
G
>A0A366G2H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter marplatensis|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGATRQDLRDILQAYKHEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQASNPSADLDHFVAKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPLAVWKELSL
>A0A1M4W150|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomonas hydrothermalis|TrEMBL
MQPISFEFYPPKTDEQRAQFDRTVRKLKAYGPEFMSVTFGAGGSTLSHTPETVQRLRSLH
GVAGAPHITCVGGSREEIRTLLKRYRALGCDRIVALRGDLPSGMARSGDLRYARDLVALI
REEHGEHFHIEVAAYPEVHPQADDAQTDLRHFKAKVEAGANSAITQYFYNADAYFQFVED
ARRLGVTIPIVPGIMPISNFSQLRRFSAACGADIPRWIERRMAGFGTDDDGIRAFAADLV
AAMCRRLLDGGAPGLHFYTLNLARPVQAVLQRLS
>A0A5A9XD79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzomonas rubra|TrEMBL
MKIIDTIIPDKPFLSLEFFPPKERSEWPAFFHTVDRLKEVKPLFCSVTYGAGGSTHGDSL
EIVGRLKQEHGLETMAHLTCVGANEDDVHTFLDQLTRAGGDNVLALRGDLPQDSTSKSSP
HRPLAHASDLVALIHDSHPQVGLGVAAYPEVHPEAASTAADLAYLKLKLDHGADFAITQL
FFDNRIYFDFVRNARNHGITKPIIPGILPVVSLKVIKRIVSLCGTVMPPDFMAQLEEADR
RGGAAEVQKLGVAHARRQTEELLAGGAPGVHLYTLNRADAVLEVTNGLCPPQGPTP
>A0A397TBR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glomus cerebriforme|TrEMBL
MKITDKINNLEPSQPFYSFEYFPPKTDEGLTNLYDRLKRMSHLDPLFASFTWGAGGSTID
RTTDMCATAQSLYGLESCMHLTCTNVVRGTIEKALKEAKSAGIQNILALRGDPPRGQEYW
TSCDNDFTHAIDLVRFIRKEYEDYFCIGVAGYPEGNPDSDNKEQDLKFLKQKVDAGADFI
ITQLFYDVNSFIEWREECRKIGINVPIIPGIMPIQGYNSFRRITNLCRIHIPSEILNVLE
QIKHDDQAVKDYGVTLAVSMISKLVNVHKIRGFHLCTMNLEKSVRLILEKLKFVQTEEER
NLRRLNRRRSSAGFVANDIIRQEPDGSLPTAKPVIWKEQSVDYLGRSEDWDNFPNGRWGD
ARSPAFGELDGYGVSLRIPPEQALRYWQNPTTLDDLKQVFKSYILGEIPALPWYEEPLYA
ETEAIQSNLVQLNELGYLTVSSQPAVDGAKSDDPIYGWGPRGGYVYQKAFVEFFVSPENL
EKLIKKIAKNPWITYYASNRNGNLKTNIKEDAPSAVTWGVFPGKEIVQPTIIEEVSFKAW
KDEAYALWTEWEHLYPKDSPSQRLLRDIGDNWWLVNLVHHNYVESEGIWDIFFKP
>A0A6G9JTW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MNMFAEYHQDIMNQKLENIRNSIQCSFEFFPPKNDFLEKNLWSSVKRLSKLKPKFFSVTY
GANTGEREKTYDIVKKIYKKTGVVTAAHLTCVDSTPIELKKIAEHYWKNGIKSIVALRGD
TLEKNYKHNMYALDLVILLKKIANFDISVAAYPELHPESKNIESDLLNLKKKIDAGANRA
ITQFFFNIESYLRFRENCIKNRINVEIIPGILPVCNFKQLKRFSKMTNVKIPQWMSEIFY
GLDNDMVTQQIIGSSIAIDMVKKLSFEGVKNFHFYTLNQSDIAYSICHILGL
>A0A7C5AKJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans|TrEMBL
MASMSKLRETLEAGDFAVAVELKPPRGTEVGGMLAPVTALRERVTAFGLPDNAQACLHLS
SLAAARLVKEAGGEPLLHLSCRDRNRLALESDLLGAAALGVENLLLVSGDYVTLGDHPQA
KPVYDADSVQLLQIAQGLRAGQDSTGQPLSGNPAFYLGAVVIPEADPLAPQLLKMEKKIA
AGAQFLVTAPVFHLERLRSFREHLTDPAIKLLVTVKVLEADELSQAMAGGWRKVYSLPQE
LLQELAGQEPAALESEAVRVAGRLVRQIKEERLGDGVYLQARGREDLLAAILKQAEL
>A0A432UGZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfatator sp|TrEMBL
MKAGSNLENVLRSGAFAVTGELGPPKSGDLQLVRKKARILKGHVDAVNITDCQTAIVRMS
SLTAALAALSEGVEPVMQMTCRDRNRIGMQADILGASALGLKNLLCLTGDHQKFGNHPQS
KGVFDMDSIQLLQMVKGMRDDKKFQCGEEIKGNEPRLFLGCAANPFADPFEFRPVRLAKK
VAAGADFVQTQIIYNVDKFAKFMEMVRDLGVHEQCFILAGVTPPKSLGMARYMKKFVPGL
DVTDDVLSRLADASDQREEGINICVDIINQVREIPGVAGVHVMAIEWEEAVPEIVKRAGL
SQRPDPEGVIPVLQSSESIERAVEEARKEVRIELEEELERAKTEAQASRELVIKEKEKVA
SEITDLKKQIEEARTMASRKEAEVQKLTEEIEKAKKELEARQALGHTGPSAVAPEPPHGP
AAPGMSPSPGPLSNREQRVLESLNLGLQALKNVLGLDDSQFEALRRFLEAEFMLQLGQVA
APAAPPVPPPPGPELHEPAPPAPEAVSPAPAPQETAPPQEAVKEEKPARNKEVVNLVAKG
NLALHSGDYNGAIDAFEKALGIDATDEKARAGLAQAKAALEKEL
>A0A423IVU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas lini|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARHLATFNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1M7SN98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sanguineus|TrEMBL
MTPTLNQLHEYRTATDTPLFSGLPGDVAVSFEFFPPKSEKMEAQLWDAVTQLRPLGPNFV
SVTYGAGGSTRERTHATVARIIAEAGLPAAAHLTCVAASKAEIREVAEQYWDAGVRHIVA
LRGDAGEPGAPFTPHPDGYASAADLVAGLKQIADFEISVAAYPETHPDALSPQDDIDNLK
RKLDAGASRAISQFFFSAEAFFRFRDACAAAGIDAPILPGILPVTNVAQARKFASACGAA
IPAWMDGLFEGLDEMPAARQLVAATVAAELCRRLYAGGVRDFHFYTLNRPELAYAICHML
GKRPVGEAA
>A0A2W7QSC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus chordae|TrEMBL
MKITEHLGNAKETLFSFEILPPLKGQSLKELLEGIAPLMDFKPPFVDVTYHREEFIYKKH
PNGLLEKISTKKRPGTVGICAAIMNRFHIDAVPHLLCGGFTKEETENALIDLNFIGVENV
LALRGDAPKTEGKFIKEPEGHGYASELVEQIIRMNEGRYLHEETEIGFQTDFCVGAAGYP
EKHFEAPSMKFDLKYLKEKVDKGAEYIVTQMFFDNQKYFDFVAQVRSAGITVPIIPGIKP
ITTIGQITMLPRTFFLDLPDPLMDELEKCKTNAEVKAVGIDWSIQQCKELVKENVPSLHF
YTMSKADTTYKIAKEIF
>A0A2C9CQX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monaibacterium marinum|TrEMBL
MRPTLSFEFFPPMSPAANLRLWTSVERLAPLAPNFVSVTYGAGGTTRARTLAAISTIRER
ARLNVAGHLTCVGATRDETLEVARGFAKQGVRRIVALRGDAPKGADKFEPHPDGFVSAAE
LVGALREEGFRDISVAAYPEKHPEATTLETDIDNLKRKLDAGATDAITQFCFDTDTFFRF
RDAAAKAGITAPIVPGILPVENFAKMKNFAGRCAAAVPAWMDQAFGNVETDAEAHLLSVS
IAAEQCSEMMAQGVDHLHFYTLNNPDLTFDICTAIGIEPIAMQGVVGGTA
>A0A1H4JN64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beijerinckia sp. 28-YEA-48|TrEMBL
MSLDVVRPSRQSNRPLRVSFEFFPPKTAEMETALWHAIERLAPIGPSFVSVTYGAGGSTR
ERTHSTVSRIIHETDLKPAAHLTCVAATKDEVDDVVRAYWDAGVRHVVALRGDPLGGIGT
AYAAHPGGYENSTALVAGIKRLGDFEISVSAYPEKHPESATLDDDIDVLKAKIDAGATRA
ITQFFFENDHYLRYVDRVRAAGIDIPILPGIVPVENFRQTASFAKRTGAFVPQWLADRFD
GLDNDPTTRRLVAAAVAAEQVFDLLDRGVQDFHFYTMNKSELVFAICHLLGLKPQLAREA
A
>I4M872|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis 00703Dmash|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFSNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VSYIRSKHPDLPILGACYPEKHPEAESLQADIENLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVQRMTSLCSSRITSQVSAMMDRWGSNAECLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A376JNX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETPQTGGREYCDGYGEDFKP
>A0A0K2AQ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL B-2516)|TrEMBL
MALGTASTRTDRARTVRDILATGKTTCSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWIPHPQGLTYAAELVELIKESGDFCVGVAAFPEMHPRSADWDADVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVTAAGCDTPVIPEVMPVTSVKMLERLPKLSNASI
PAELEERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSPRA
>A0A4R1HGK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia endophytica|TrEMBL
MIESLLAGSAGVLVCDGAMGTMLHAAGRPLDQQLPHLNVSDPELVRAVHDSYLHSGVDII
QTNTFGATRLRLDEAGLAARTEQINRAGTQIARQAAVAVGRPVLVAGSVSPAITVHQRGR
VSAAARAEALAEQMDVLVSAGVDALVLETFGHLDELVEAVGIAEGRGVPVIAEATFAEDE
RMLSGHTVADLARAVPPHRVAALGANCTLGPQGCLSVVRELGRHTTAPLIAQPNAGLPRR
VGPSRFEYVIDSDYLVRYVRQLVEAGAAVVGGCCGTTPAQIGAVVEIVREYRRAPAATPA
AVGGVREVVSGAGTTAVAGRTPFLVAAEFVPPAPGETDRMVSTARTLREVGVDTVVVAAS
RAPRARVSTVNLAVHLGDRAGVDPVVSVPTWDRTIMALQADLLGAHALGVRRIVCETGSP
PLLGDYPSVDGVWEVDSVGLIELLVALNAGRDHNGVGLTATTTFEIGARVNLGRDDLDAA
LRQAHTEVDAGAGFLLTEPVYELDGLDRLLAEFDPRRTPVIVSLRPLTTFDEVEYLRHEI
PDVRIPDSTVREFERAGAQGREVGRRIAAELATGIAERAQGLVVCGTEAADVGYVERLVT
ACRAAASSQPLRS
>A0A8F8BXR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQVARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQASPKPMLACLMSLTHGRATMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALETRIEYWQTQVQSLEQWAPA
WHASWQMPGLPAVTFHPPQAGWRLDESRVDASFKEKARYHLMHGMHALLFSRRNSLSKAF
GWAVRQPLWGTRVGAHVLHTLERSVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A7U9FXK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli TA143|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8E2LEY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heyndrickxia oleronia|TrEMBL
MNIVEKLKSSVLVADGAMGTLLYSYGKDTCYEEFNLSHPDEIINIHQAYIQAGAQVIQTN
TYGANYFKLSQYGLEEQVKAVNTEAVRIAKKAANKETIILGSFGGYRGIRKADITLSEIK
RSFREQLFHILNEGVDGILLETFYDVEELLAIVEIAKKESDLPVIAQFSLLEPGVLQNGM
ELREGLYRLEEMGADVIGLNCRLGPHHMIQSLEEIPLPKNAFLSAYPNASLLDYEDGRFV
FTNNATYFKDCAVQLVKQGVRLIGGCCGTTPEHIRAITEGIEGLVPITKKVVKPSKEKIE
LAITQVPTEPPLHEIVKGRTSIIVELDTPKHLQTERFIEGAKALKAVNIDAITMADNSLA
SPRISNVAMGTILKEQYNIRPLVHITCRDRNLIGLQSHLMGLDALGIDQVLAVTGDPSKI
GDFPGATSVYDVSSIDLIQMIKQFNEGLSYSGKSLRKKASFSVAAAFNPNVRNIDRAVGR
LERKIKSGADYFITQPLFSEEKIIEVYEATKHLQTPIYIGIMPLTSYKNANFLHHEVPGI
TLTDSILSAMERAADDPLQATTESLAISKSLIDTAMEYFNGIYLITPFIRYDLTIECSNY
IHAKENVVHVTNRI
>A0A6B3ESN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID11233|TrEMBL
MDSLSTATAPALAPLLDDFSLEMTGKDVPGLEAARDLIPAGTRINITFLGSEDLDTRLSA
ARAVRRLGYVPVPHVAARRLRSRPELEELLAALRSDGTADNVLVIGGDPATPHGPYDDSL
ALIRSGMLQSYGVRHVGIGGYPEGHPAIAGPALWSAIEDKTTALAGQGLSGDVITQFGFD
ADPVLAWVEAVRKRGIDVPVRVGVPGPAGIKRLMTYATRFGVGTSTSVAKKYGFSLTNLM
GTAGPDRFIRALAEGYDARRHGVLKLHFYTFGGIGATSRWVTEFRAGEGG
>A0A0J0XV34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutaneotrichosporon oleaginosum|TrEMBL
MPHLTAIMADRKVPFHTFEFFPPRTAPGMANLLDRIQRLSSPPLNAPLAVSVTWGAGGST
AERSLELAEAIVAMGMEVILHLTCTNMPKVKVDTALERARSLGITNVLALRGDAPRPDEY
AEAESSQTIDEFNHADDLVRYIRDKHGDFFCIGVAGYPTPHPDAESAAADMHWLKNKCDA
GADYIITQLFYDFGQFEAWVAACRAAGVTQPIIPGVMPIQSYSSFRRLINLTKCVVPEKI
LRDLDPIKSNDAAVKQYGAQLATDLVKELIESRLVPGVHFCTLNLERSVRTILENVEWTL
DHAHPVHGSPRARHNQLISDEALPTVEGQPISIRASDATQLAQWSLSRAAAAATSPTKLP
PIPGVIPGVGEDPWDEFPNGRFTDVRSPAYGEIDGWGSGLKITPTQALREWGTPTSAADL
ATVFQAYLRGDERTPTTPFCDMPLSPESSLILPHLLALNSADKAYWTVGSQPAVDAASSA
DPMHGWGPVGGYVFQKAFVEFFVPLSEVQRLEAKLVSMSAEGADGSPTQSLISMYAANRR
GDYATNTQKDAVNAVTWGVFPGQEIQQSTIIEEISFLAWKEEAFEIWQEWARLYPRGSPA
RSYLDGVADEWWLVSLIHHDYKDKDALWRFLLE
>A0A1L7NKM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFETDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A352MN63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp|TrEMBL
ETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A0F2R4L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatitalea sp. BRH_c12|TrEMBL
MKLRDALSNRKFVVTSEVQTPLGDDSPEQLVDRLKRIRGRVDGVTVSDVELEGVVGDSIH
TCELLQRNRFNAIYQTTTRDKNRIQLQKDLSLAHQSGIENLLVFTEDYRITGDSVQEEMF
FHVDAGKLGSVLEHIRQGRGIDGEELTSPFDFTLGSGIESPWGRKVPKQGMQGMETLKIM
GAGFFLTTPIFDLEQFDKFMRQIRSLEVPVIAEVLLLRNAAMARFINRHFKPSLVPEWVI
QKLDRAPDKTQASIELFGSLARGLREVCHGLHIITLGGEDKLKPYLDAANLR
>N9E239|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter beijerinckii ANC 3835|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKTVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDADIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKVGVNIPIAPGIMPITNASNLIRFAEGTGAEIPRWIRKQLAAYGDDSSSIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1H2GGG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula phenolica|TrEMBL
MRVNELYKNKQPVISMEFFPPRNQAASEKFGGLIDTLAAYNPDYMSITFGAGGSTRDGSY
QTVKELIVDKKLPTVAYIAGYGLGPDDIREVLDSYRELGVETIFVIRGDQPKTDDAALHP
DSFLYASDLISFIKSNYDFTLGCAGYPEGHIEAKNLDQDIQYLKQKVDNGAEYVVAQYFY
DNDYFFNYVDKCKDQGINVPIIPGIMPVYTVKMTRMLSKICGSAITDELDQKLNFLDSED
KEGAVKLGIDFAAEQCRGLLKQGVPGLHFYTMDRSKSTGEIIAQLKQENLL
>K0NCA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula toluolica (strain DSM 7467 / Tol2)|TrEMBL
MSFLFSDDNDFIITIEVVPPAGNDPTAILEKLCNLSGLRFHAFSVASNPVAKPRMSAMVF
THLVQQATLKPAILHCTVRDHNRLGLQSELWGAKALGIETVIAVTGDPSSSRAEESTSTV
GDLNVFQLIALARESDLDIGAVLDFRPEVNGLKHEVKRLEQKVASGCRFIVTQPVYDEKT
AKAIHTATQHLDVPVIMGILPLLSYKHAVFLHDKVDGIAVPKFLRQQIKTAENPVKTGVD
QSRQMLELGKSYFSGACIMPPFDRFDILPDILSNF
>A0A2H3IJM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium sp. 'occitanis'|TrEMBL
MAQALRPLFVTVTWGAGGTTAAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQA
KALGIRNILALRGDPPRSEEYNMDGDDDSNKDFTWAIDLVRYIRKTYGDYFCIGVAAYPE
GHPGESQTDIQDPEKDLPYLVEKVQAGADFIMTQLTYDFEAYQKFEDRLRNHPSGAIKTI
PIIPGLMPIHGYKILTRVTKLSGAHIPPAIMSRIEQVRSDDERVKQVGVDIVSEIANQIK
SLPNPGHRGYHFYTLNLEKSVTLILERCDLIPPSSDDSAIEDGIAIEEVDANNKGLKTLV
SRRRASSINSGPHNRVIVDKLHVPTDQQSEHSSRKSITYETLASSAGVPALNPPPRSTQL
QISEGIGSLGREATWDDFPNGRWGDSRSPAFGEIDGYGPSLHVNATVAKQLWGFPVSKED
IGTLFRKHVSGELYIVPWSEGGAAEDANLNAETQVIKPQLLQIIEKKNWWTLASQPAVNG
VRSDHPIFGWGPPGEGFVFQKAFVEFFCPTSDYQNKVKPTLLKHGSEEFSWFAINAAGHL
ESSFLLSASSSPKSEDASSAIAADEEPVEVRESTGMAVTWGAFRGREITTPTIIEEVSFR
AWGEEAFRIWDEWRRIYPRGSATERFLNETKNDVWLLCVIGHRYGAGTEPGSEEEKAEMN
TLWNVLAGDM
>K0NE43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula toluolica (strain DSM 7467 / Tol2)|TrEMBL
MNLKESLEKKRFVVTSEVQVPLGDEESEGLVESLGRVKGRVDGLSIAEIELEGVVSDTIK
TCGLLKENNLNAIYQTTTRDKNRFQLQKDLTLAHETGVDNLLVFTEDYRISGDTLQESMF
FHVDSGKLGSVLNHLKQGVTIEGKELESKVEFSLGSGIETPWGKSMPKRGMEEMEDMMNV
GAGYFLTTPIFDIDQFAKFMKQVEPFRVPVIAEVMILRTAGMGKFLNRHFKSGLVPEWVI
QKLMNATNKKKASMELFADTVKSLKDICQGVHIVTLGGVDNLVQYLNAAKLR
>A0A6B3FBJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID11233|TrEMBL
MTMLREALHRPAPSFSFEFFPARTPAGMRALWQAIRQVERLAPDFVSVTYGAGGSSRERT
IEVTKRIVAETTMRPVAHLTAVGHSVAQLRHIIGQYADAGVRDVLVVRGDPPGDPNAPWI
PHPDGLRYAHELVSLVRELGDFSIGVAAFPERHPRSPDWESDIRYFVAKCRAGADYALTQ
MFFQVEDYLRLRDRVAAAGCDIPIIPEIMPATDARQISRFAELSGAAFPEDLAHHLDAAR
EDPARGFRIGVEYATAMAERLLAEGAPGLHYITLNRSTAALEIHRAVTGSRSVRRAEMLH
G
>A0A716UBX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Typhi str. CT18|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPDL
>B8E333|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyoglomus turgidum (strain DSM 6724 / Z-1310)|TrEMBL
MNFEQKLKSGKFVITAEVSPPRGVDVSSFIEKTLLLKNRIDAVNVTDFQNVGVRITSLVG
SYLLLREGFEPIFQITARDRNRVAISGELLSAYALGIRNVLVLTGDYTTTGIVKSAKPVF
DLDATNILVIAKKLEEGEDFSGKKLNKSPDFFLGAVFNPNLVPLEIEILKLLKKKKAGAE
FFQTQLFFELSLMERVRDRVGDDVKIIAGVTIFKSLEMLEYMMDNVPGIKIPERVIEMFK
NTKDIKALSIEFCVEFCSKLKESKLLDGIHFLASRPSDIIKVLDLLKW
>A0A7C8B2T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium|TrEMBL
MKIIDRIKPDTQFISLEFFPPKLREDWPSFFQTVERLATLQPLFASVTYGAGGSTHDNSL
DIVTRLKCEHGLEAMAHLTCIGSAPNELLTFLERLADAGVDNVLALRGDRPTDMPPEAAA
ATTLQHASDLTAFIRSSHPGFGLAAAGYPETHPEALSPESDLQYLKLKFENGADFAITQL
FFDNKLYHDFVARATTAGITKPIIPGILPVVSLKVIKRIVSLCGASIPAEFLAALEEADQ
RGGSAEVQKIGLAHARRQAQELLASGVPGVHIYTLNRSELVLELVDGLLP
>A0A837FTZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. SM3|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSILKPKFLSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWDNGIRHIVALRGD
LPPGGGKPEMYGADLVELLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPTLTA
>A0A8C4NQT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dicentrarchus labrax|TrEMBL
WPQHAPNCMECEVPPNAACSFNLRDGSWQSSKSDSSGASNSGGESSKDSSRCSTPVLDAD
RSDRLRDKMRKRMESGDRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGD
PGSDKETSSMMIASTAVNYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDP
VGADWEEEEGGFNYAIDLVKHIRSEFDDYFDICVAGYPTGHPEAESYEGDLRHLKDKVDA
GADFVITQLFFRADTFLKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEI
TKVIEPIKDNDAAIRNYGIQQAVDMCRLLLDSGKVPGLHFYTLNREVATMEVLRQLGLWI
EDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGEL
NDYYLFYLKSKSSKDALLQMWGEELINEESVYEVFTCYITAQPNSRGHKVMCLPWNDEPL
APETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSE
NVTALLKVLKKYEPRVNYHIVDVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVADPVSF
MYWKDEAFALWIEQWAKLYEDESPSRMIIKYIRDNYFLVNLVDNDFPLENCLWQVIDDMF
ELLDASPEQTLGQ
>A0A6I6WT14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium brasiliense|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWQSGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTTMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A7V8UXW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. D2|TrEMBL
MTKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALCA
RGETDIAPHMSCIGDDKSEIAELLEHYKSLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFKLDIDNLVNKYQAGANASITQFFYNADSYLYLR
ESLEKRGIDTVAQPLVAGIMPITNSSNLMRFADSCGADIPRYVRKQLADFGDDSKAIREF
GFEVVYRLCERLISEGVPAMHFYSMNKVEPNKRLIEALGLIA
>S7X7B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis 17/34|TrEMBL
MTMSRQTPSLSFEVFPPNPAVGNDKIISALRDMQELAPHFISVTASNNKFNIKETTVRLA
DFIQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYA
TDLIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERF
YDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLR
AAGLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2N3XK25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 5112.2|TrEMBL
MNPALTAPPDGGTPGPHGAESQERATGLLDDFSLEMTGKDVTRLEEASDSIPPGTRINIT
FLAGEDLATRLTAARAVRRLGFVPVPHISARRLPSRAALEEFLSGLAADGTAENVFLVGG
DPARPEGPYADALALLRTGLLQEHGVRHVGISGYPEGHPAIPDPTLWSALTDKAAAIGAH
RFGGDVITQFGFDPVPVLGWLEAVRARGVHLPVRIGVPGPAGVRRLLGYATRFGVATSAS
VARKYGFSLTNLMGTTGPDRFLHALAERYDPARHGRVKVHFYTFGGLRTTAEWAARFRHE
DHAPTGRP
>A0A8B8IC51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vanessa tameamea|TrEMBL
MLPKITELLKNVQDISYSFEVTPDIAEEELDNFDLEPLFFSITWHAQTHQCINLEIAPLK
LANYLRSKGKNVLLHISCTNMRRDYVNMLLTTLQDKGICNLFIILGENFDPSRSDFKSSQ
ELIIYVRERTGNYFCIGVAGFPNCDDKLSHLKDKVDSGADFILTQAFFEHKIYERYIIKC
REVGINVPIVPGIFPFETKGELAGFTDLCKVRVTNNLIKKLENISGIEVVARLINDMLEQ
LHVKHFHIFTLNKLPRTAKLIGKINSNIK
>A0A0S8CHF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium SG8_35_2|TrEMBL
MNFFRELEKSNSFPVCYNLLPHYTAEEQDYNALARCVKEAVQDGRIQTFFLSDQPAYRQE
FSSLSLAEDILAAGGEPIVSLSMTFHDRNSVMDRLQKYHQAGVQHFLFVSGDYPTGTENK
TPKPVFDTDSVQLLMLLADFLEEKSIAKGCVVCPFKSFESEQIWQYEKFRRKVSAGADFV
VTQLGYDIRKFDELLGYCGLHKIAAPLVANIFATDMQTARLIQARNIPGVRMPSSLLRDL
HGETSDRKGIIARTAKTLAVLKGLGYHGALLGSSKNDFSEIKQIVDKNEDLHHEWRNYVT
ELDCSDGPSTRFYYFQKNPQNGLNSREPAPVALKHFPSPTYSFSYFIDWLVYVPQGPLFK
LTGRFCHFCSTRKFWYAFLWLLEYVTKHPLYGCNMCGDCTLYACGFLCYQSGCPKKLLNG
PCGGSIDGYCEVLPEKKRCYWVKVYHNMKGVRQHVTFVTPAIPARDISLHRTSSWINFFT
GKDHRKMKFEET
>A0A1V5V3M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium ADurb.Bin242|TrEMBL
MKPSGIQLEMNFDGPRGNRFKEKLDNGIFQLLVEINPPQDNLSLDDAVARFSEIEYVVSA
KQDFPAALAFTDRLAAPGNGMDTVRFASALCKTDRDKHLLCVSGRDRTVEEIEKILAHAS
HEGFRNILAVSGGSLPGDTLKEVQSRLYTESVHTIRSVRERFNPLLLAGCAVNPYRYTPG
TVFPQYFKLMRKIGAGASFIVTQFGWDMLKLQELRWSLARRSMHLPSIARFLMLTPDRAE
EICSGKVPGVHISPDLEAMLRREMTHSLAQFEAAQWRRIQIHAAGARFLGYSGVQIAGAE
RADHVNILLNRISEALAEFSSFEEWRSAYSDYYARLDMAPYPYRFYEFEGLFSSAQPSDS
PVMSPAEFLPFEGLELFKHRLARRLFAHADAMPASEKRLTKKLLVSCRSCPACRLPKTDF
VCPETCPKGMANGPCGSARAGGECELFPRECIYSKRMRIASHYNEFGSLEEGLVEPVSSR
R
>A0A0M9DCR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MRKQSFSVEIEANPGDLRQMKHYLHKWQPDFVSISNLSRYSYEEMVQCARYIQTDLHIPV
VIHLTGLTHTKEEVKKAFNQLMGLNIRNFLLVRGNIHHNMHIKDDFNYASDLIKYVNQLD
TDSKINVVAGCYPDIHVLADSLTEDIEYLKQKVNSGVDSLISLMCFDNKRIYKFLDKSRE
SGIKVPIRIGIMPITDPFKRHYLAHNDVKMPEFSEEEDNLLENGINYAVNQINDLYEHNV
NGIHLYTHNDWMVSDRVFENIKQNL
>G5J9X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocosphaera watsonii WH 0003|TrEMBL
MINHFRQAVQNKEFLITAEVAPPKGGNPTRMLEMAKQLKGRVHGVNITDGSRAVLRMSSM
AASALLLQYGIEPICQMTCRDRNAIALQADLMGAYALGLRNVLALTGDPIKAGDHKRSKP
VFEVESVRLLKMIDKLNEGIDFNDKTLADEPLDLFPGAAVDPQSRSWSGLQKRFERKVAA
GAQFFQSQLITDFEKLDKFMHQIAANSDKPILAGIFLFKSAKNAQFINNNVPGVEIPESI
IKRLGEAEEPLKEGIKIAAEQVKQAQKLCQGVHLMAVKREDLIPEILDQAGIPPMVSQ
>A0A0Q5JL72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Leaf151|TrEMBL
MTLLPLIDACPKRMEYGPCGGVGFDGSCEIDAAHRCTFLPRRTVPWTGIDRTTPVDPGRR
TAAAAETLASLGTRPWIVADLPARALSVTSIDACAAVLTGEVDAVLAGDAGSARVQFPPA
YRAHLLQRRGLRVWTGLNMRDRNRVAIEGELAALAVEGVAGVHCVTGDHTRTGHRPDAAP
VFDLDSTEATALARAAGHVVSVAASPAAPPVERRAARLREKLRAGADVCFVNHAGGAEPV
RRFIDEVGDGILFIPCIPVVVDGASADLLESFTTLVLPDGFLGRIRDARDPRAEGIALAV
ALAEEMLALPGVVGVNLSGGREGAEESFAEALAEVARRVC
>A0A2W7JRU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. URMO17WK12:I6|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKNDLRGLLTQYKAAGIQRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEIAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERIQAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQSFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A139DGH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. T13-3|TrEMBL
MESQKQFKRRFSFEFFPPKTDKGREKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LSLHRQGISTAPHLSCVGGTRQEIGELLDLYKENGINRIVALRGDMPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARSAEDDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSESIRQ
FGEEVVTRMCEKLLAAGAPGLHFYTLNQAQPSLSIWENLGISDREKIAF
>A0A317UBL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. BCRC 81119|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPGTIEHLMKYRPEYISCTYGAGGGNVGANRE
VCQMIRNAGTVPVTHFTVIKNTKEGIRQQLEQYLADGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A1E4I105|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. SCN 72-86|TrEMBL
MTTRPTDSRTAFADAVRRAGYEVLPFPSTHDKVLAHVPVEVPLTVTTTEAKGLEPTLDLA
VRLRAAGYRVAPHLAARLVRDKEHLTDIAARLGGAGVDDVFVIGGDATEPVGVFPDALSL
LEALGDTGYTFGSVGIGGYPEGHPRIPDATLTQALQDKAPYATHVVTQLCFDAATTTRWA
SRVGLPVHVGVPGAVSRQKLIRVSAGLGLGQSARFLTKQQSMFWRFFLPGGYRADRLLDK
LAPAFTGPLAGIHVFTFNDLEATEEWRQNLLARLS
>A0A0Q7NV43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia sp. Root136|TrEMBL
MVQSLRTHSGSNVPFSVEFNPPRDAAGEARLWRAVREFERMHPAFVSMTYGAGGSTRDRT
VRITGALAQETTLLPVAHLTAVGHSIAELRSLIGSYADSGICNVLVLRGDPPGDPLGEWA
KHPGGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLDHDTRHLAAKLRAGAEYSITQ
MFFDVEHYLRLRDRVIAMDPIEGAKPIIPELMPITSLRTVARAEELSGRPVPADVVARLT
RAAGTGPEEDRAAVRAEGIQIATEMAQRLTDEGAPCLHFITLNFAKATSEVLTNLGYGVT
AAPLSA
>A0A317UD67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. BCRC 81119|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVQLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAEI
>C7GI33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia intestinalis L1-82|TrEMBL
MRLTELLNTENVTISCELFPPKQGAQLDNYKKIVGDMAALKPAYMSVTYGATGGTSDYTV
ELANEVRNVNHIPALAHLTCASSTKEKVASVIQELKEKQIENVLALRGDIPQNADFPLPN
QYKHASELIYDIKSQGDFCIGGACYPEGHPESQTLEEDLIHLKEKVDAGCEFLTTQMFFD
NNILYNFMYKALKHGIDVPVVAGIMPITNANQVKRSIALSGSLVPRRFLAIVDRFGSDPA
AMKQAGIAYATDQIIDLIANGVNHVHIYTMNKPDVAGAILENLSDIYVRD
>A0A7V9PP32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MLDDVRLELIPIAGFEAQVEQLPPDAVVPVTCSPRVGIEATLRASAYLRDRGHRPVPHIA
ARMVAGPSHLREIIGQVDDLGLSEIFVVGGDIKDRVGPWDGGGALLEELTTFDHHVERIG
IPAYPETHPLIGRADLTGFLKAKQPYADHMVSQICFDPDTILAWVADMRAQGVTLPLHVG
IPGPMEVRKLLATSLRIGVGASARFLSKQRGLAAKLLSRYRPDHLVSALAPYMDDPDYAI
AGFHVNTFNQVKATAEWLEAMRGTDLQTAS
>A0A1G0MYT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium GWC2_53_11|TrEMBL
MKENKNSILKRLQSEVLIGDGAIGTMLYAKGVSLDSNFDHLNLVRPKLVAELTREYIAAG
AQVIETNTFGANSTKLSAIGLGHKVEEINLAGARIAREAAGDTVLVAGSVGPLVPLKGSE
HVLGNTQIEDAFRVQCRALAQGGVDFLLLETFSSLDQLQLAVKVARETRLPVSASLAFLE
GGRSSDGSSVEKFCQAMEAAGADIIGANCGAGPLELLKVIKRMAAVTDKPISAYANSGFP
EYLDGRYIYRATPEYFADMAAEMVAAGANLVGGCCGTTPDHITALARTLSGKPPAVRSKV
PVISVAEPAQAQPIVTSFLDNWGKRTVITVELDPPKGLDCSKIIAGCRRLKEAGADAINL
AENPLARPRMGNIALGSLIQREVGIEVIVHITGRDRNLIGMQSDLMGASLLGIRSILAVT
GDPATMGDHAGASSVFDLHSFTLIKLLSDMNSGVNAIGNPIGSGTGFTVGAAFNPNTKNM
GVQAERLRKKIAEGARFAQTQPIYDPDILLAALEATRDCTIPFLPGIMPLVSERNAEYLN
NEVPGISVPDAVRARMKGLDKEAGVREGLSIAREFIDATFGRVGGYYLIPPFGKHELAVE
LITHIQQHEKENR
>A0A3T1D919|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella abietis|TrEMBL
MKPDLRTALAQRPIVGDGAMATYLYQLGLPVGVSFEEFNLLKPDVIADVHRRYAAAGAEV
IETNTYSAQHNKLSKYGLEKKTEEINAAGVAIARKAVGHDAYVIGSIGAVRGGAGKNVRT
AVVKRDFEEQIGVLLATGVDGLLLETFFDLEELSLALSIIRKKSDISVICQFAVEDAART
HDGIPLPEAFRRLKGEGADVIGFNCRSGPNGILRAIETIPGDLGVPLSVFPNAGIPDYVD
GKVIYSASPEYFASSAIKFADAGARLIGGCCGTTPEHISAMAKALQSYSPLVHVSTPSDA
PTVEQVEVIEVKEDPSHNAASTEPPHNAEPSIVDLVRERHTVIVELDPPRDLDITKFMAG
AQALKDAEADALTLADNSLAVTRMSNMALAALLKERVGIKPLAHIACRDRNLIGTQSHMM
GFDALGIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGRPLKQKAN
FIVGAAFNPNVKHLDKAVQRLERKISAGADYIMTQPVYDPDLIERIAESTKHLSIPIFIG
IFPLASGRNAEYLHNEVPGIQLSDSVRERMSGLEGPAGRAEGVKIAEELLDVAMKHFNGI
YLMTPFLAYEMTVSLTKYVREKSKSMVSGK
>A0A7W3R5I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Curtobacterium pusillum|TrEMBL
MSSPTTGTGTDVRPILADFSVEMTAKDVDAMLEAAQSLPPGTRINVTFLGNEDAGMRRAA
ARAVRDAGFRPVPHISARRIADRDELDDFVGALHADGTSDSLFVIAGDPPEPIGPYDGAI
DVITSGIVGRYGVRCVGVGGYPEGHPLIPEADLWSSLEQKVAAIAEAGAEGEIITQFGFD
VDAVLRWVDGVRQRGIDLPIRIGVPGPAGIKRLVGYARRFGVGTSAGIAKKYGFSITNLL
GTAGPDRFITELAAKYDEHRHGAIALHFYTFGGLRATAEWIQEFRKESAR
>A0A7L3YTT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fregetta grallaria|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPDAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7V9CES6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIDELLTQADRLPLFSFEFFPPKSPTGEENLKQALRELEPLSPDYVSVTYGAGGTTRET
TIEIVSHLKEDFGIEAMAHFTCVNATTDELRATLDRMRDAGVENVLALRGDPPQGAERWT
KTDGGLEFSRELVELIRDEYPEFAIGGAAFPETHIHATSPEDDIRYLKEKVDAGMQFVIT
QLFFDNAHYFDFVARAREAGVEVPIIPGVMPITSYEGIKRMTTLTAAELPAPLERELVVR
KDDPEAIQELGVSYATLQCAELLSGGAPGIHFLTLNRSPATRAILAALRLTKPWLAAQPV
>A0A7C8BSH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoclavibacter caeni|TrEMBL
MSAAVPSAGSAAAAGFDEPDERRFSASRFDELDEAVFDDADDPGAVADLDGELRALRAEH
RARRLRERHADAVPLPSVAAPTRSIEVFPARSLRQLRRNVASVRTMLGLGTDFVTVTYGA
AGSRQAGTKELVGWLVEAGVPTYAHLTCQATDLAALDATIDELLALGVTGVLALRGDPVA
DGGGLVLPHATDLIARVRQRAERAGRAPDDPLRIAVAVFPTGHPDSRDLVEDAENVARKQ
DAGADFAITQNFFDAADYERFMTLVDRTGATLPVVPGLTPTPSVRRLERIAELSDLTPPP
ALAAALAEAPDDETRRDIAVRTTAELAERLAHAGAPGIQLFTMNDATTAVRILRMLDDVL
DRHHPDRTPGHQATGAESTSWQIDTQGPASKAAPSSATRASGGAAS
>A0A7K5PMG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrocercus mccallii|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A268TQA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. 12S02634-8|TrEMBL
MIERCVQKLLNADFLSYEISPPKAPSIGEGLLKELQGWDQFDALVCTDAPLAKFKQSAIL
TSLKLQNALQKPVICTLNMRDRNTIALQGDILGANELDIRLFLTLTGDPIKLGDRPSAKG
VFEGNSLLLAELIHSFNQNKDLDGYPIKGQIKPIYPFGVINSYSNNPLSLKNKMRRKIAS
GMLALFTQPVYDTEVAKLILQWCAEINQELGSHAQVVFGYFPILRYKTAHFLYSKLPGVF
VPKIWLDELEKAQKLGEKEEEKVGFALSQKLFEDIKNIHNKIHFMNSNKIALAKQILQ
>E0RX36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio proteoclasticus (strain ATCC 51982 / DSM 14932 / B316)|TrEMBL
MKIRDIIKDKEVTLSFEVFPPKTDAGYEAVEKAAAEIAALKPDFMSVTYGAGGGTSKNTV
NIAADLQNKYGTPVLAHLTCVSSTKEHVKEVVREYKEKGIENIMALRGDIPKEGRICYDY
DHAMQLIYDIKSIDDSICIGGACYPEGHVECARQSEDIEHLKEKVAAGCDFLTTQMFFDN
STLYQFLYRIREKGIDVPVLPGIMPITNAKQVARSVALSGSTIPQKMKIMVDRFADDPEK
MKEAGIIYASDQIIDLISNGVSHIHVYSMNKPDIAAGIMRNLATIIR
>A0A4D4LRH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces violaceusniger|TrEMBL
MHSSTDQAGRQAPPGLLDTVSLEITGKDVKELRSAAAQIPPGTRVNITFLGNENMALRVE
AARVVRELGFRPVPHVSARRLRSQEDLKDYLAALAEADAVEEIVVIGGDPPEPEGPFPDA
LSVISTGLLGAHGVRHVNVAGYPEGHPKIDDDVLWKAVEQKWAALREQNLACSVTTQFGF
DTGPVVAWIEKLRAREINSPIRVGVPGPAGVQRLLRYARRFGVQSSASVVQKYGLSLTGL
LGTAGPNRFVESLETELDTDRHGDVSLHFYTFGGVRATAEWIQNARHE
>W9D101|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. CcI6|TrEMBL
MAAVRSLSTQPTTMGEYLATGRASFSFEFFPPKTPDGERQLWTALRQIEALHPSFVSVTY
GAGGSTREGTIRVTERIATDTTLTPIAHLTAVNHSVAELRRVIGNYAGVGVRNVLALRGD
PPGDPQGTWTAHPAGLRHADELVRLVRSVGGFCVGVAAFPDKHPRSVDFDSDARYLVGKF
DAGADYAITQFFFGADDYFRLVDRVRRLGCDKPIIPGIMPVTNVAQIVRMAQLSGAAFPP
ALASRLQAVADDPAAVRAIGVEVATELSRRLLDGGAPGLHFITLNRSSATREIYQAVR
>A0A250WYQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlamydomonas eustigma|TrEMBL
MKIIDKVNQKIAANEKFFSFEFFPPRTQEGVEALFERQERMVAHGPVFCDITWGAGGSTA
DVTLDIATTMQSQICIDTMMHLTCTNMPVEKLDEALKEVKKHGLQNILALRGDPPKGQEK
FEAIEGGFNCALDLVKYIRSEFGDYFGICVAGYPEAHPDTIVEDPVQMEKNYQENIAYLK
NKVEAGGEFIITQLFYDIDVFFKFVKDCRSAGINVPILPGIMPIMTYGGFKRMTGFCKTK
VPQELSDKIEELKDNEEALKLFGMDHGADMCRKLLAGGVPGLHMYSLNLEATVFGILERI
GFIDTAKVPRHMPWRLVPMGTRRQVEGVRPISWANRSRSYITKTSCWNSFPTNSWGAEQS
KLLSLAIADSSAKSRNMSEGRKKKSLEAWGSELSTLEDVKAVFTKYFKGEISLFPWSDAP
AQSSASVLSRVEALINTDVLPIHVQSSVHDVASEDAGAGWGGPGGYVYQKGYVEAFVSPS
KFKELLPKLKSSSNLTYVASNNGGDVHSNASASGISAVTWGVFAGKEVVQPYIFDKDSFL
SWKGEAFSLWESGWAALYETGSASSQLLKDMQSSWYLVAILDNEFVPKDPLAIFGA
>W1Q8J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ogataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1)|TrEMBL
MKVTNKLLESHKEENAPATFSFEFFTPKTSQGLQNLYDRMDRMYDLNPLFIDITWNAGGR
LSTLTTEMVQTTSTVLGLETCMHLTCTNMKTDLIDQALRSAYESGCQNILALRGDPPLDG
SESTGDFKYAKDLIRYIRKHYGDHFCIGVAAYPEGHPEESDPVKTLKYLKEKQDAGADFI
VTQMFYDTENFINWCDECRKIGITMPIIPGIMPISTYAAFIRRAGWSEIAIPKHFSEALE
PIKDDDAKVREVGTKLVIEMCQQLLESKRVNHLHFYTMNLEKSTLMILQGLNLVTKQQLH
DMKQPWRKSLNPNRSKETVRPIFWKNRKFSYISRTANWDEFPNGRWGDSRSPAFASVESC
ESELIRHSPKKALELWGTPNSLKDLAELTMRYINGELSCLPWSDGQISSEIEPTKKQILD
IVKHGILTINSQPSVNGLKSSDKVFGWGPRNGYVYQKQYLEFLVPSTVVSLLIERINEMN
KGADSNILSFYATDKDGHLITNTQDSDIIAVTWGCFPGTEVIQPTIVERISFLAWKDELF
SILDKWLSIFRHEKATQATDFLSSLCDSFTLVTVVDNDYVKSPNARIFELFQDIDLLA
>A0A4R0KY91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella pittospori|TrEMBL
MANGLASTRPGNRPTIRELLASGGRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWVAHPEGMNHAIELVELIRSLGDFCVGVAAFPDKHPEATSLEADAQVLAA
KAQAGADYAITQMFFGADDYFRLVDRAAALGCDIPVLPGVMPVTNIKQIQRMAELTGMAL
PTAVTDRLLAVEDDPAAVRQVGVEIATELCEQLLAGGAPGIHFITLNRSTATRQVFLNLR
SSVVS
>A0A7J5X236|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp. YY1|TrEMBL
MRIALYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFMPPRDAEGEARLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSVAELRALVGAYADQGIT
NILALRGDPPGDPLGEWIKHPDGVEYAEELVRLIGTLGDFHVGVASFPEGHHRAPDLEHD
TRNLVNKLRAGAEYSITQMFFDVEDYLRLRDRVQAADPEQGAKPIIPGIMPVTSLASIKR
MAELSGSVIPPKVVERFARAAGDGPEEDRAAVRAVGIDFATETAERLIAEGAPCLHFCSL
NFAKATSEVLARLGVDVDAALHVPA
>A0A1F8SGU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_72_14|TrEMBL
MSLRQTLLATPDFATVVELVPWAGELDDARGQRPLKMAVDLAGDPRITALSITDNAGGHV
RLGPVAPAEPVIELGHDVIVHVACRDRNRSGLQSRGWDLLSRGLTTVLAVSGDYPVEGFD
GLSKPVFDVDSVGLLALYRELGEAAVARAAADGVPDPAEHAFFLGCAVANVKRFERELIP
QYLKLALKVRSGAGFVISQVGYDARKQDELLRLMRRDGIAIPAIANAYILDRGVARAFHA
GRVPGCVVSDKLLALVEQRAAGPDKGRAFFLEFAAKQLVVARGLGYRGIYLSGHRDASEI
SRVLEYAEAFAEADWHDLVADVTFPLPGSFHLFERDPATGLNSDVVSTAYRRSLEPAARR
RARAGVDPFYRVNRMVHDRVFTEGTPGFRFWGSVYGRVERAHLAKPLHVFEQAVKVPLYD
CRDCGDCSLPDLAYLCPESHCAKNQRNGPCGGSQDGRCEVGERPCVWAEAYRRLKPYGEE
LTMLERPPILQDNALRRTSAWANTFLGRDHFAKQKGPRS
>A0A1F2SF39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium RIFCSPLOWO2_12_FULL_59_11|TrEMBL
MGTMLYAKGIPFQRCFEEMNLFLPSLVKEVHEAYLKAGAEILEANTFGANPLRLATFGLR
EKCREINHAGVRLARHSIGEEGLVAGAVGPLGVRLEPLGPCSAEQARTAFQEQIQALAEA
GADLIMLETFYDLDEIREAIAAARAVGDLPVIAQVTIGDDGNMPSGTPPEDFTPKLLAWG
ADAMGCNCSVGPKVMLETIQRMAPLSPRPLTAQPNAGLPVNVGGRNIYLCSPEYMAGYAS
HFLRSGVKLLGGCCGTTPEHIRAIQEAVQAVQPLRPRILWSAVPAALEPEKALDPIPLAE
RSRLAHKIAAGRFIALAEVIPSSGSDPTKEMEGSRYLAGAGLDAVFVRDGWQAGARMSAQ
VLAHLIQDRTGIETVLQYSCRDRNVVSIQSDLLGAHGLGLRNLVLVTGGPSKKDNYPDAT
TVFDVDAIGLTKIVANLNRGLDLGGNFLGSRTSFSIAVSANPGAVNFEREIERLETKVQV
GAESVVTQPVFDLEKLERFLEQTKPLGIPFLVGIYPLTSLRNAEFLANELQIPIPASLLE
RMKAADSGEAARAEGIRIAQEILVWLQGRVQGILLSAPLGRYSTVVEVLNAIGPHEEKNV
ATHDTAAGWQTRQTI
>A0A8I1J4B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium rosae|TrEMBL
MTKTEADRQTRGNFKLSFEFFPPKNADMDVQLWETVEELSRWNPDFVSVTYGAGGTTKAP
TLVAVDRMISVAGLSTASHLTCVDASKQEVHDVVEELRGIGVKHFVALRGDPSTGPGTAY
KPHPDGYENAAALVRGLREIDDFQISVSAYPEKHPESESTDVDIDMLKRKADNGATRALT
QFFFDNAMFERYMERVTKAGITIPVVPGIMPIQNLTQLKRFAGRCGTTIPAFLDERFAGY
DENPVERAKVAADVAAEQILDLQSKGINEFHLYTMNRAPLVNAVLENVGFRPLKQSAA
>A0A2C0ZFB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS041924|TrEMBL
MGLLKKLNEGIVLGDGAMGTLLYSGGLHSCFEELNITERDRIIHIHEQYIDAGAEVIQTN
SYGANAGKLRQYGLEKLVKQINQMAVRNARAASKGRALVIGGIGGMKYVGSTFTTQLERE
MMLLEQASALLEEGVDGIMLETFYDENELYDAVNLLRGRTDLPIIAQVTLQEIGVMQSGQ
YIEKILPNLIDLGADVVGINCHLGPLHMLESLNTVSLPTNGYLSAFPNSGLPLYTEGKYV
YKSNPEYFEDMAKPFIEQGVRLIGGCCGTTPAHIAALRNKIDTLQPVTKKEVKNRTIKIT
IPKQPEEKNETLAEKAKKRTTIIAELDPPKTLQTRKFFEGAKALHIAGADAITLADNPLA
SPRISNVAMASLLQRLDVPVLTHLTCRDRNMIGLQSHLMGLSTLGLNEVLAITGDPARVG
DFPGATSVYDIASLELIRMIKEMNEGRLYSGKSLGNGTRFSVAAAFNPNVRKFDAAIKRL
EKKVEAGADYFLTQPIYDFETIDKLYEATRHINQPIFIGIMPLVSKKNADFIHYEVPGIT
LSEEVRNRISSVEPEKAVDEGKKIAKELIQYVKDKFNGIYFITPFLRYEITEDLIQFTKS
SNKEEIQL
>A0A0A2HZ25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp. Tol-SR|TrEMBL
MTTETQYNSGSNLEKVLKSGQFAFTGELGPPRGTDVDEVKEKARFLKGNVDAVNITDNQT
AVVRMSSWAASLIAIEEGLEPNYQMVCRDRNRLAMQADILGGYALGIRNMLCLSGDHQQF
GDHPDAKGVFDIDSIQLIALVKQMRDEGRFLSGGDIHKPPKMFIGAASNPFADPFEWRVH
RLAKKVEAGANFIQTQCIYNMPKFREFIRLANEEGLTDRVYILAGVTPMKSIGMARYMAS
KVPGMDVPEEIINRLKGVEKSKVAQEGINIACEQIEEFKAMKGVHGVHLMAIEWEHMVPQ
IAEQAKVLPRPVFS
>A0A1M5ZSJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 3214.6|TrEMBL
MALGTASTRTDRAHTVRDILATGKTTYSFEFSAPKTPKGERSLWNALRRVEAVAPDFVSV
TYGAGGSTRTTTVKETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDTDVAHFVD
KCRAGADYAITQMFFEPEAYLRLRDRVAAAGCVTPVIPEVLPVTSVKMLERLPKLSNAHF
PDALRERILNSKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A2E2B635|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaeraceae bacterium|TrEMBL
MAVILSDISVGYAGWVWGMRFVMFDVVPQNVLMSSAKSPLECIPEGQCPKGLCRGPCSDT
LNGHCATLPQRACVWLEKLPDHTAMDMYGMEEDGSWTDMVGSQLKRKMLAGAFVELCEIH
APRSGRLGDFVDQGRMLKPYFDAMTVTGQIKGRPVMPSAEASGHLRAIGVESIAVLSGRD
CDATSLQAELAVLQCNEVGNVICLSGDGGDPKAGPVQMASVDMLRLAADVHDERRPWLGA
VINPFSTPASLPMIQLKQKLQAGANFLLTQMIFDLPAFETFFKALTVDGLAERARVVAGV
PVVVSEYGLELAARLPGVWLPQEVEQQYEQAADIREFGIATARQTLAALRQIPGLAGVHL
MLLGGHDPSDLLAVMQ
>W7YPA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharicrinis fermentans DSM 9555 = JCM 21142|TrEMBL
MTAAELVLKNKETKFSFELLPPLKGNNIDKVFKTIDILKEFNPQFINITSHREEYKFETN
DKGYVEKKVVRKRPGTVAVAASIQNKYGIKVIPHIISRGFTKAETEYALIDLNFLGIHDV
LLLRGDDAHKDKYPERSEDCNQYAIELAEQVNNLNKGIYLDGTSNDAFTTPFAYGVAGYP
EKHEEAPNMDSDLRYLKAKVDAGAEYVMTQMFFDNQKYYDFVDKCRAMGITIPIIPGIKP
ITTANQLTVLPKIFSCDIPEDFAKELRKCKDNEQVKQVGIEWCIQQALDLKKNGVPIIHF
YTMMATQSTRKVAEAIY
>A0A0J1CRK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia mineralivorans PML1(12)|TrEMBL
MKPIELSFEFFPPKTQEGIEKLRATGAQLKALNPKFVSVTFGAGGSTQQGTLDTVLEMMK
QGLEAAPHLSCIGSSKDSLRGILGAYREHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFNIEVAAYPEYHPQARSPKSDLENFVRKVQAGANSAITQYFYNGDAYFRFVD
EARKLGIDVPIVPGIMPITNFSQLMRFSEMCGAEVPKWIARRLESFGDDKEAIRAFGLDV
VTGLCERLVREGAPGLHFYTLNGAAASKTICERLGLPKA
>A0A4R7JN96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter spongiicola|TrEMBL
MKVTDHITNAKGKTLFSFEIVPPVKGKNIQELYSNIDPLMEFKPPFIDVTTSREETIYVK
KEGLLDRKTTRMRPGTVGICASIQHKYDVDTVPHVICGGFTKEETEYMLVDCHYLGIQNV
MALRGDARSEQKYFEATDGGHPFAIDLVKQIQDLNCGKYLHETIESEHCSDFCIGVAGYP
EKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEAAKSIGITVPIIPGIKP
IAVKRHMQLLPQVFRIDMPQDLIEAVDGCATNKDVRKVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAEALF
>A0A5J6HEK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces alboniger|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTGTVKETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGDWVAHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSPDWESDTRHFID
KCRAGADYAITQMFFDPAEYLRLRDRVAAAGCETPIIPEMMPVTNVRQLDRLPQLSNAVV
PAGLKDRILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHRQA
>A0A6L5JYV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclus tenuis|TrEMBL
MTADLRNASRCFSLELFPPQTPEGTEKLRAVRRQLAELGPKFFSVTFGAGGSTRDRTLDT
VLEIQTDGQEAAPHLSCVGSTEENIREMLTLYRGQGIRHIVALRGDLPSGMAEPGAFRYA
SDLVRFIRAETGDWFHIEVAAYPEFHPQAASPQADLAAFRSKVDAGADSAITQYFYNSDA
YFRFIDDCAALGVTIPVVPGIMPISSYSKLARFSDTCGAEIPRWVRKKLESYGDDAASIR
AFGLDVVSQLCERLLAGGAPGLHFYTLNQAGLVNELWERLHLPAHAARGTELASGL
>A0A426XKF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensete ventricosum|TrEMBL
MKVIDKIRGAAEGDGRTVFSFEFFPPKTEEGVENLFERMDRMVAHNPNFCDITWGAGGST
ADLTLDIANRMQNMICVETMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQD
KFVQVAGGFACALDLVWLISTCTTFALNMGTTLVSLLLAIQISSVLEAHPDMIQGDGGAT
QEAYNNDLAYLKRKVALCSFDLLLSHLCLSFEQVDAGADLIITQLFYDTNIFLKFVNDCH
QIGITCPIVPGIMPINNYKGFLRMTGFCKTKVSTVVLYLLSLLLLWKFSIL
>A0A7L9WLP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudopuniceibacterium antarcticum|TrEMBL
MTVPAVSFEFFPPKNLEASFKLWDTVQVLAPLAPRFVSVTYGAGGTTRDLTRDAVATLHK
HMGLNTAAHLTCVNATREETLAVADSFAEAGVTELVALRGDPPKGAGQFSVHPGGFANSI
ELVEALADKGKFTIRVGAYPEPHPESADTAADVAWLKRKFQAGADEAITQFFFETETFLR
FRDDCARAGITKPIVPGIMPIENWKGMRKFAAGCGAAFPDSLVDMFEKADRDGRADLLAT
ALCTEMCDRLLSEGVENLHFYTLNKPELTRDVCHALGVTPQSRLENVA
>A0A415I4X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF39-11AT|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFNTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>K0DAT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc carnosum (strain JB16)|TrEMBL
MTKISEIYHTKPAPVLSFEIFPPKKEGDIESLYQTLNDVDPLALGVDYISVTYGAGGSGN
NIKTRDLAQYIQEHFGVTALHHLTGINQTPEVLQDQLADIKQAGIENILALRGDLPDADY
VNAYYPYAKDLIRDIKQFNQFNIGAAIYPEGHVDNPVTGISVAGVKEKVVSGTDFLISQF
FFENDVYYNMQDALKSNYIKVPVSAGVMPIISKAQVERMTYMIGSSLPSRLVKIIHKYEN
QPDSLKQAGIEYALEQIHDLLNHGVDGIHLYAMNRPSVLKSMLPVINQDIQSKSLDFP
>A0A373LYN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF36-4|TrEMBL
MIKDLFHTNRPTYSLEVFPPKKDADVSVIYDALDEFKTLHPSFISVTYGAGGNTAENTFA
IASYIQNQCGIEALTHLTCAAIPDRLFLKNFLTNLYRNGIHNLLALRGDKPQWMSDEQFD
ARYYDHASDLVTDVKEMFDFSVAGACYPEVHQEAASLSEDIANLKIKVDKGVDFLITQLF
YDNETFFRFLDEARNAGITVPILPGLMPITSAGQVKNIIGMSGTKIPKELADAIEKYKDN
PADLKKAGLDYSKRQMENLLAHGVDGIHLYSMNKVEIAKAIYE
>A0A1H3T3C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbiconiux ginsengi|TrEMBL
MSASSAASSSSSASEPDCPTVPFSFELFPPRSQQAARAVRETVAVLAAAHPEYISVTYGA
NGSSRDSSIDLLRYILETTTVRPLAHLTCVGSSHAEATTIIREFLEAGVSSFLALRGDPP
QGSSEDEIELGDLGSASELVQLIHRVQAERMPYIEEDVPGLPRASRVKDGRRRLEVSVAA
FPKGHPRSSAGFHDVDALLAKQVAGADFAITQLFFHADDYLGFVERARAADVTMPIVPGI
MPVTTPSRLRRIAELSGQDVPGDLHSALESAPDDDARFRIGVAHASALARAVIVGGAPSL
HLYTFNQHQAALAVLRECGLVPSPPIKEYA
>A0A1D7VHT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lydicus|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVKHPDGIAYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVD
KCRAGADFAITQMFFYAEDYFRLRERVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPDLAERILAVKDDPAAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A364P0G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum kuznetsovii|TrEMBL
MSFPLSELPIACASRRPVSVSFEFFPPKTEKMQQSLWECVQRLEPLGPQFVSVTYGAGGS
TRERTHETVVRIARETKLRPAAHLTCVGHSRGEVDDIARRYWDEGIRHIVALRGDMPDGQ
PYAAHPDGYAYAVDLVQGLKRIADFEISVAAYPEKHPDAPSADFDLDNLKRKIDAGASRA
ISQYFFDPAVFLNFMERCAKAGITVPVLPGILPVTNFAQVQKFSAACGASVPDWMANLFE
GLDDDPESRRLVAATVAAEQCRILAQNGVEQFHFYTLNRADLAYAISHILGVRATAKKD
>A0A355SLY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halieaceae bacterium|TrEMBL
GIDKPIVAGIMPITNFANLARFSRNCGAEIPRWICQRIEGYGNDQESIRQFGVEVVTQLC
QTLLENGAPGLHFYTMNQVEPTRQIRNNLGL
>A0A0X6ZQ14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. LY4|TrEMBL
MIIKRITHKLPDISTASIIPASIEASPAQVLGSTDLAGLFPQGVRVYLTDTGAASQERLV
EAAGHLRDLGYEPVPHLAARRIPSRAAFEEQVKRLAEEAGVTDVLVVGGGVDRPASPFAS
SMDMLSTGIFDRCGIRQIAIAGHPEGSPDFNEETAMAALRLKRDFAERSDAVMRIVTQFG
FDPARFIAWAEGLAASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESIVGPIERHWQANPQGPIRQVHVFPFGGLQNSADWLVKRGSWQTGAADRSAS
PDSMAG
>A0A1J5FKC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium CG2_30_36_16|TrEMBL
MKVIEHIVNAKNPLISFELIPPKRGGDIKSLLAVLDEIIKYNPPFIDITSHSAEVIYEET
PKGIKKKVKRKRPGTLGICALIQNKYNIEAVPHILTKGFTREETEDFLIELSYLGIENVL
AIRGDDSGYDKPIPEGRSKNTYAVDLVKQIVDMNHGKYLEEGLLDARASNFCIGVSGYPE
KHFEAPNLKTDILHTKQKIDQGAEYVVTQMFFDNKIYFNYVDKCLKAGIDAPIIPGLKII
TNKAQLQTIPKNFYINIPDELSDEVYAAKPEHVMSIGVEWATKQVEELLNKNVPSVHFYI
MLDSRPITMLMKRLKLF
>A0A1F3VDB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium RIFCSPHIGHO2_02_FULL_44_7|TrEMBL
MKVTELIKNSAEPFTSIEIIPPKKGLKLQALFTELEQLMRYKPAFMSVTSHAHEKSVETV
NGKEVERIKSRRLDTNAICISAQARYGVEPTPHVICRGFTKDETEDVLLTLHFHGIKNVL
ALRGDAAPAASGTAFANEYASELVEQIQRMNQGIYLDPIDDAEKTDFCVGVAGYPEKHFE
APDFETDLKWLKHKVDCGADFIITQMFFDNNAFYKFRDEAAKIGIKVPIIPGIKPLYKKE
HLESLPRIFYTNIPASVKESISRFNDPEDIYKAGIESTIAQCKDLLANGVPGIHFYSMGI
AKPTSDVLNGLALLNHHV
>A0A2V8JY39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MQDLLSRLEDHVLVCDGAMGTMLYSKGVFISRCFDELNISNPQLVREVHFDYINAGADII
ETNTFGANRTKLMTHGLAEHIREINSQGARIARDIAGDKVWVAGAIGPLGIRIEPWGKTA
IEEARAIFREQAQALADGDVDVFILETFFDLNEVYAAIRGVRDITDRPLIVQMSIEEDGN
SPEGTPPEVFAKRLEEWGADVLGLNCSVGPQVMLDAIERIAGVTARKLSVQPNAGKPRNV
EGRNIYLGSPEYMASYAKKFVQYGVRIVGGCCGTTPQHIKAIRAAVKSAGSVVLGPSLGT
PSARRLPPEGQGAASIPLESKSRLGGKLARREFIKIVEMIPPLGHDFAEAIEKAKYLQAQ
DVDAINVPDAPPSSARMSAISLAVLLEKSTEIESLAHYTCRDKNLLGMQSDLLGAYALGL
RNLLLLTGDPHQIGEHSDATAIYEVDSIGLTNMVNRLNHGVDVGGKSIGKPTGFVIGVGA
NPGAMNDLESKRFFYKVDAGAEFVLTQPVFDAAVLERFLDRSGNSKIPVIAAIVPLPNYK
TAEFLNYEIPGCSIPDAILNRMREAQSKSPDYARNEGIFIAREILERIHGMVQGVQIRGP
FDRYETPVEVLSVILKGATP
>A0A7Y3DXS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MTAPRISFEFFPPRTEEQQLVLESTWQKLAPLRPEYLSVTFGAGGSTLEATRETVAALSA
STDVPVAPHLSCMANSKAMLRDILVAYRDMGVDRLVVLRGDRPEGQSGPGPFQYANQLVE
FVRGEFGDHFHIEVACYPEFHPESESAETEMFYFKQKVDAGADGAVTQYFYNADAYFSFV
DESRRQGIDIPITPGIMPITNYRQLSRFSAMCGAEIPQWIRRRLEAYGDDGASIRAFGLD
VVTALCERLLAGGAPGLHIYTLN
>A0A2V9HH09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKILDFNERLKDSILIADGAMGSMLHDAVGTQRCFDEVNSTEPEAVFRVHQAYIEAGAQI
IETNTFGANRFKLEPLGLAEEVQRLNSRGVKIAREARESAAREVLIAGSIGPLGIGVQSR
HPFPEEILDIFHEQALALEERGVDFYILETFAYIEELLLAIDAIRSFSGLPIVAQLTYAE
EGTTYGDVRPADAAAQLKNKNVQVIGANCTLGPQALLPILQELAAVDDLRASGMPNAGFP
KREGDRIVYPKSSPEYFALFAREAAALGVRLLGGCCGTTPAHIRAMAEAVKSLRPAKSHA
AGHAAEVISKPAPVTHRIPESKFWKKLQKKEFTVCVEIDPPKGLSLDRIFEQVDKVMASR
KVDAIDINSGAMARVGMDALIVASALEARGIETVPHLTTRDQNIIGLQAALLGAWTVGGV
RNVLAITGDPPSVGDYPETSGVYEVDSVGLVKVLNRLNQGTDWAGKTLGGATNFTIGVAV
NPVADDLDNEIERFHAKVEAGAHFAMTQPLFDPEHWHAFLKKLGGKPAIPVLIGIWPLNS
YKQALRLNNEVPGIVIPEALLKSMENAGAAARDRGFEVARKMLDWSRTELAGAYLIPPFK
RYEEILEIL
>A0A7T4R8R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium ASx5O|TrEMBL
MTTLSFEFFPTKTDEGTDNLLKVRDELAPFNPEFFSVTYGAGGSTRDRTFAIVKAIQERG
IAAAPHLSCVGDSKADLRDLLTRYKELGINRIVTLRGDLPSGSGLASSELRYANELVEFI
RAETGDHFTLEVAAYPEMHPQATSFEKDLQNFVRKVKAGADSAITQYFFNADSYFHFVDR
VRAMGVDIPIIPGIMPITNYSKLARFSDSCGAEIPRWIRKQLEAYGDDSDSIVKFGEEVV
TDMCRRLLDGGAPGLHFYTLNQSKPSLAVWKNLI
>A0A7C5TVV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRLILAGRTRSNDPFIIPHSPRLWYSLAMDLERRLVDHVVVLDGAMGSELLARVPEIPSI
DLAALTHPAEVLAIHLEYLQAGAEILQTATFAASRPRLETLRAGDRTEAVNSAAIKLARE
AREVAGADCLVAGSLGPLAALLDPDDPRAHAELMEAHAEQAAILAGRGADLLVLESFFRL
DELELALDAVASATSLPVIALMTFPAGRPPHPWGNMAAQVARLAEREVAAVGLSCAPGPM
GTLEILERIPPLARPLAVEPNAGVVVHRPDRELLSPATPAYLGRFALRAVELGAAMVGSC
CGTGPEHTRAIAAAVAGLAPPAARKPSVSVMAAPEERPATPPPRQPRSSLAEALVSGRFV
RVVQIDPPRGANSSHLVEAVRTIATTAAIDAVDINSNPLGRLRMDSLWLAAEIERETGVA
TIPHVTPRDAGIMGLEAQLLGAWRAGIRNLLAITGDPSTLGDYPGHMDVNHVDIFELVRT
IRRMAAGEDWSGNPIGDPPAFFTGVAVNPHAADLAHEADRLRRKIEAGASFIMSQVFFEW
APWERLLELFGGGLPVPALVAVWPLTSLKLALRLHYEVPGILVPEELLRRLEDAGPQAGR
VGTEHARRLLAEAPSFAQGAYLIAPFKRPERILDLLEGLSRCAEPG
>A0A2V9L7J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MREPFLEKLEKRPLISDGAMGTMLYAKGISFSRCYDDLNLSMPQLVKEVHLGYVKAGAEV
IETNTFGASAPRLKKFDLDGKVREINLAGARLAREVAGDDLYVAGSVGPLGIPLEPLGPT
SLEEAREIFRQQIAALVEGGVDLIVIETMIDLTEAHQALLAARDVAPLPVVVQMTIQDDG
ATPTGTLPEDFTRRLDEWGADLIGLNCSAGPAGVLETLERMAQVTARKLSAQPNAGLPRT
VQGRSIYLCSPDYMASYARRFIQAGARLVGGCCGTTPEHIKAIKDAVRALRPQPARAAVE
VSSQRVRVMEPVPLERRSKLARKLARREFPVLTEIVPPKGCDPTREIEGAQYLLNQRVDA
ANISDGAGSTARMSAQTLAAVIQQRVGIEVLLHYSCLHRNVLSIQSDLLGAYALGLRNIL
AVTGQPPALGAYPAATAVMDVDSIGLVNLLNNLNRGLDVGGNPMGTQTGFLLGVELNPYA
LDPDEELRRFHYKVEAGANFAVTQPLFDAAHLARFLERIDAAKISRIPVLAGIHPLTSFR
HAEFLNNEVPGVSVPPAIMERMRKADTGDQARAEGVKIAQELLREVRPLVEGVQIAAPFG
RYAMSVEVASVLGEHATATRNSAGSGG
>A0A2V8L749|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MHTFQDLLDSDRSYIFDGAMGTMLYSKGIYINRSYDELNLVAADLVREVHSEYVRAGADI
IETNTFGANVNKLQPYGLEASAREINIKAAQIAREAAGNRALVAGAVGPLGLRIEPYGPT
SFDEAKQLFADQVSALLEGGVDLFVLETFSDISELHHAIRAVRELCDLPIVAQVTIQIDG
NTSFGTTAEVFTTQLDEWGADVIGLNCGVGPAIVLNSIEKMRTLTSRKLSAQPNAGLPRD
VGGRQIYMCSPEYMAEYSRRIIQAGAKFVGGCCGTTPAHIKMIADAIRQFHPRTQQVSPS
TVAKISLHELKPPDVTVVPAEERSNWSRKIATGEFVTTVEVLPPKGCNPWKTLDSIRLLK
DAGVDGVNIPDGPRAQTRMGAMATALMVQKEIGMEAVLHYCCRDRNLLGMMSDLLGAAAM
GLRNVLLITGDPPKMGPYPDATAVFDIDAIGLTNMVNKLNHGLDIGDNPIGEPTAFSIGV
GVNPGAVNMEEELRRFEWKIEAGAEYAITQPVFDTQQLRDFLKRIESFRIPIVAGIWPLV
SFRNAEFLHNEVPGVQVTPEIMERMRNASAISKEAGRDEGLKIGRESLVEVRDLIQGVQV
SAPFGNVKYALEVFSVLPELAQKEAAAPGVS
>A0A7W0L8B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MSSPEQGRLRAALRSGRFAVTAEIGPPRGADAQAIVGKADLLRDWVDAANITDNQGSHTR
LASWAGSILAMRSGVEPVMQLTTRDRNRIALQSDLISAGAVGIPNVLMLSGDHPTFGDHP
DAMPVFDLDSVQLIWTARLMRDQGRLLSGKPVRPAPQWLIGAVENPFAPPLRFRAQRMAK
KVAAGAEFIQTQFVFDLEIFSRWMGEVTDLGLEKRCGVIAGVGPIRTVRAMEFMQSKVPG
IHIPDQVVRRLRGVTSDQVAAEGMALCVETIEALREMTAVAGVHVMAFGQEHVVPELLER
AGVPPRTATAPSATAGSNREDHDAR
>A0A2N6SCX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemella sanguinis|TrEMBL
MRNLLERLENNVLVADGAMGTTLYSNGLESCHEYNNISNPSAVEEIHRAYIEAGADIIQT
NTYAAKKCQLKTYGYEDKFEEINIRAAEIARSAAGEKTFVLGTIGAIRGLRECELTLESI
VNETLDQVKVLLSTEKIDGLLFETYYDQEEIRTILSEVRKLTDLPIITNISLLEAGITQN
GEKVTDALSALVNLGADIVGLNCHLGPYHMIKSFKQVPLFAQSYLSAYPNASLMQLTQTI
NGNEYRFRKNSSYFEQSAKLLVEEGVRLIGGCCGTTPEHIRAIKKGIKGLKPVKRKTITP
LPAEEELIRVASNKPTIVDKVKKQVTIIAELDPPKHLNIEKFIEAAKTIDKKNIEAITLA
DNSLASTRICNLTAAVLLKEHITTPTLLHLACRDHNLIGLQSRLMGLDLLGINNILAVTG
DPSNLGDFPGATSVFDVTSFKLIPFIKQLNEGLGYNGASLKKTTNFTVAAAYNPNVRDIS
KTKRLVEKKIKSGADYFITQPVFEEEKIVKLSELASNYPDTPFFVGIMPITSYNNAIFLH
NEVPGIKLSEEFLSRLEEVKDDKELCQKIALDESKKLIDVALKHFNGIYLITPFTRADLT
VELIDYIETVKTK
>A0A6M4MF14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas pelagimontana|TrEMBL
MVSYAQGIDALNQSLSELRDIEVSFEFFPPNSEKMEQTLWKSVERLAPLKPAYMSVTYGA
NSGERDRTHDVVKRIHQQTGVTAAPHLTCVDATRDELKQIAKDYWDSGIRRIVALRGDLP
PGLSKTEMYASDLVTLLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTSVFLRYRDRAAAAGIDIDLVPGILPVTNYQTLIKFAGFTNVHVPGWLHKMYEGL
DEDDQATRNLLGANIAMEMVKVMAKEGVKHFHFYTLNRSELSYAICHMLGLRRQKN
>A0A7V5CXN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSPNKSNLQAKLESGKFVVTAEAGPPRGARPEVMREKAKILKGCVDACNVTDNQTSVVRM
CSLAACKILCDEGIDAVMQMVCRDRNRIAIQSDILGAAALGICNLLCLSGDDQIFGDHPQ
AKNVFDLDSIQLLKIVRQMRDESKFAGGKDVDGAPNLFLGAAANPFADPFKIQVPRLAKK
VAAGAQFIQTQCVFNLERFDEFMKGVRDRGLHEKTFILAGVTPLKSAAMAEYMASKVAGI
DIPSPIIERIKGVEKKKQKQEGIKIAVETIQKLREIEGIRGIHIMAIEWEEIVPEIVQQA
KL
>A0A7Y4XC01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MNNFRAFLQADRVRVFDGAMGTMIYSKGVYINRSYDELNLSTPDLIANIHREYIKAGAEI
IETNTFGASRLRLAKQGLDDKLVDINTAAVKLARNAVESAKHDVFVAGAISTLGVRLEPY
GPTSLDEARALFKEQAQVLLDSGVDCFVLETFHDLAEMQQAILAVRELCDHVIFAQMTIN
ERGETAYGTAPEVFTERLDAWLGPDDVIGLNCSVGPQTILEAIEKMRQVTTRRLSAQPNA
GNPRDVGGRHMYMATPDYFGEYAKRLISAGVRFVGGCCGSTPEHINMMVGAARALSPGRT
SVAAITVEDTASQAVEPMPFAERSRWAKKIANNEFVTSVEIVPPKGCDPSSMLKGVQLLK
DNGVDAVNVPDGPRAQSRMGALAVSLIIEQQVGLEAVTHYACRDRNLLGMFSDLLGAAAL
GLRNMLLVTGDPPKMGPYPDATAVFDIDAIGLCNLVNRLNHGIDPGGNSIGEPTKFVIGV
GVNPGAQDLDYELRRFEYKVEAGAEYAITQPVFDTAQLKHFLKRIEHCRIPIIPGIWPLV
SFRNAEFLNNEVPGVNVPDHILERMRKCEDSNAALKEGIAIAREMLAEVRPYVQGVQVSA
PFGRVPFALEVFEELR
>A0A6L8E044|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKRIPDIYAEKGAAGRPVVSIEFFPPKTPQGDESLFERVLPRLAEARPDFCSVTYGAGGG
GTRARTLSIVDRMQREHGLTAMAHVTCVSFTRVEMNGFLDEAAELGIENILALRGDPPPG
EPDFVRPAGGFDYAYQLIDVLKARSDEFAIGCAGFPEGHPDCTEAREVDWRRLRDKVDHG
AEFILTQLFFDNADYFRMVDHLTGPLGVAVPITPGILPILSTKQVKRFTALCGATLPPAL
VADLDRLGDDDEAVTEFGIDFASRQCEALLAGGAPGLHLYGLNRSRSALAIVRNLGLAAS
GLPAVRSGTAG
>A0A7X8UGQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRLGGHAFATGAESPFLPIDRLVARLGAAIAQKLAAKGNRFRNAMTDPDTFCLVWEQIPG
PGAFETRQELVLENAHRAAAGGKVCAVSITDNPGGNPAIATDILCAEIRKAGVEPLVHIA
MRDRSRNQAESLLFQLAALAVHNVLVLTGDYPSNLGFTGKSKPVFDLDSVNGLRLVAEMN
RGMVREIMRKPVRLAPASFYSGVAFSPFKQMEAEVMGQYYKLQKKIRAGADFVITQVGYD
ARKMHELPLWLKLQNHSLPVLAGIYVLSHPVARTMNANHIPGCVVTRKLLGEIAAESAGG
DKGRQARLERAAKMYALARGMGYKGAYISGQGLPFESVEYIVARGNELAADWMRLVPEFD
YAQPNGFYLYERDPRTGLNTEAPALRTQPPARPAIYRVSQAVHSTVFEPGGALFRPVRRM
MERIDRSPFWKRVLHRVERCSKNSMYACKDCGDCALFDAAYLCPVSQCPKDQRNAPCGGS
FEGWCEVYPGEVECIWVRAYRRLKSEGREGEIAETIVPPCDWELWQTSSWINYFLGRDHS
SKQKGILPPEKKRV
>A0A2V7Z5L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKKDFRQAVAEDVLLADGAMGTLLVSRGASPDQAKSPLNVSDPEAVRDVHEDYRDAGARI
VTTNTWDANRVKLAAHEWADSLEKINREGVRLAREAAAGEMVFVAGSIGPLGALVKPYGT
LTMMQVREIFQEQARVLLEAEVDLVLLETFGSLLEAAEAVRAVRDLSEQIPILAGMTFLA
DGRTAFGESADHALSTLAMAGADVVGMNCTLGPQETHDVFSRLPASIAAPLSVMPNAGYP
TVVHGRNVYLSSPDYLRGYAEAFVESGAAVIGGCCGTTPEHIRAMARAVSGKKRAAATGR
AAVRIEGPALKIGPPVIETSRLKRRLADRNAFVVTGEIEPPRGVDLSAAIEGARLLKAHG
ADAANVTDNPMARLRMSSIAVAALIQREVGLDAVVQITTRDRNVLGLQSDLLGAAGLGLK
ALLCLGGDPLKIGDYPQGKQVSEVDVLGLIRMAKGLNAGADLAGNAIGSATQFAIGCAAN
PAASDLDVELSKLRAKIEAGASFAQTQPVYDAEALERFLACDEAQAIPVLIGLIPLRSLK
QTMFFANEVPGIVVPEAVQERMRRAAEKGTEHEKAEGLAIARELAVAIHQVARGVHVMPM
GKYKLATEILEAIPLESASSLRTRVSGA
>A0A2V3JD69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanophagales archaeon|TrEMBL
MGDEVYSQLMKELKEGKYVFTGELEPEKAGDVEEPIKAARELVGLVTACNVTDNPQSFAY
VSSLAASYKIQQETGMECIYQLRCADRNRNALLSDILGAGVLGLRNILALTGDHVSLGDT
PDAKPVYDLDSTTLIALIRKVVDEGKDLAGNEIHNPPKLHVGAAAAPGAAVLKAEIAKVK
RKIKVGAEFIQTQVVYYPEVLDRFFKELGKVDIPVLVGIFPAKTYAQADFFDKYVAGVDV
PPDYLQNMKATKQIKDKEKRKEEVDRVNIEFFTSFLEHLKDTPAAGCHIMAVGYPRIIPE
LKKVME
>A0A087RTE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marine Group I thaumarchaeote SCGC RSA3|TrEMBL
MTIRYEANPPKILPDVDTDQSIKKFIERIKNISKKCDAIHLTENVLGFQRVSPLEVGKII
KEEIPDLPITVSLRVRDKSEEEIFEFAEKCVEIGFAGILVLMGDPSQTGKADSGQIPSLT
VKKLREKNVDSKINLYLSVSNKPNFAKLAKKKDARPKGFMTQVVQNTEQVQALSDNLKEF
SIIPIILFPSQKNEKSAKFLGLDLESYSKEFEELLRKSHEITGDVLLTSPNDFTGLNEFL
GKTTF
>A0A3M1WE39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRRKFIELLDQEIILADGAMGTVLIGRGVDPNALAEQNLVNPDLVRSIHLEYIRAGARLI
ETNTFLANRMKLREYGVEDRLEEINRAGVRLAREAVQASEEEVFIAGSVGPLGALVKPYG
NLTLADLANAYIEQMSILVEEGVDLIIIETHPSLLEALEAIRAARTVSTATPIIAQMTFL
EDGRSKFGDELRRSLEALAAADADVVGVNCSGPQMTYDIMERFLRETDLRVSVMTNAGLP
QLVAGRQIYLSSPDYLREYARRFAEAGANIIGGCCGTTPEHIRTMAEVVRGQVPRRIREK
RATVVTVPAAVAPEPGARVPLQTRFQEKLGREFVVTVEVTPPRGVDCTDVIDRCRQLVEL
GIDAVSVSDNPGPRVRLSSVALAHLIQSHTGMEVILHFACRDRTLNMIQSELLGAAALGI
KNILALTGEPSVAGEVPQVTSVFDVNATGLVRILHGFNHGCTVAGQDIGQPTAFRIGVTV
NLAADDPEAEMRLLEERVEAGAHFALSQPLYDVGILERFLDGIGEFPIPLLVAIMPLTSG
RHAEFLHHEVPGILIPETLRQRMHQAREPKREGMRIAEELIRQLRPHVAGIHFMVQGEAV
ATVRELLSRSIAQTHPPLSN
>A0A7Y3HAG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MISGDHKQIASELVVDGSVEFSHGDVEQIEAIAERLPYQMPVMVPCLPRRPLESMLPALQ
AIQEASLEPVPHIPARHVESTRALAKFLQQAGVRKAVVIGGDRSSAKGPFADATALLSSG
CLAENGIREVGFAAYPEGHPTIPAEALFNSLSKNIDLASGQGQGSFIITQFTLSPQRIPD
LCSRLASAAPDTPVYAGIPGPATHEQVVHFARYCGVSTSLTAVSGVGVKLAQVVDHERPG
QQLGLLASYCAAHPGSNLVGVHIYGFGGMGETAKWIRRHINP
>B1I327|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforudis audaxviator (strain MP104C)|TrEMBL
MRGVSGLARLLGAGHFVVTCEVGPPKGVNVDGLTEKAALLKSFVDAANVTDCQTAVVRLS
SIAACVHLAAMGLEPVVQMTARDRNRIAVQSDLLGAYSLGIRNVLCLTGDHQKFGNHPGA
KGVFDLDSVQMVEMVRRLGAPGEFQCGEPVCGEPPVFFVGAVENPCAEPLELRVRRLEKK
IRAGARFVQTQCVYDLDRFRHFMGLVRARGLHEHAHILAGVTPLKSVRMARFMRDAVAGV
YVPDEVVARIEAAADPAAEGVAMCVEQIAALREIEGVAGVHIMAVAWEAIVPEIVRRAGL
YPRPADDEPKDRNR
>A0A2E7NGZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MHIIDKINQRISEKKPFYSFEYFPPATEAGLHNLYARIEQMVALEPIFVDITWGAGGSTN
EKTLSIAENLQKFFGLDVMMHLTCTNMPIEQLDEVLEKARAAGIRNILALRGDPARDSSV
WQRVEGGFTYAYELVSHIRERFGDEFCIAVAGYPEGHLEAGNKDTCTGHLKHKVDCGADF
VITQLFFDINEYAGFLERCDEQGITCPIVPGLFPIQTFDRFKKFVQFTGANVPTEVWDCL
EPIRQDDAAVRSYGVELCIEMCEKLSGLGVPGYHFYTLNLQSSVMLILEGLGAADELAVD
RQLPWRPSTFPTRREEDVRPIFWSNRPKSYLARTMDWDEFPNGRWGDRRSPAFGTLNDYY
LLRRGIGLEEKDQKLLKAYGNPKSLEDVYDVFARFCAGE
>A0A0P1B8I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceraceosorus bombacis|TrEMBL
MSAGTSSATGSQAIPAHVGSSHGALHGDSGTLFPAKSTACPHPSHIPSILSHHSSTRPAI
SLEFFPPKTSSGLQNLYARILRMKTQCGPSWMQVTWGAGGSTQNISMVLAGRVHKGLLRP
ADLDWTRWKSPSLEGESRNKTLEEREIEAIVEAPANDELATECCLHLTCTNVSREALDIT
LKQARAIGIRNLLALRGDPPRGSEYWTPSDNRFQHAEDLVRYIRSGHGDWFSIGVAGYPE
GHTDSLTPSGEAEIPVLLSKQRAGASFIVTQLFYDVSLYHSWLANARAAGITIPIIPGVM
PIQNYTSFRRITGLCKIQVPQELRRRLEDPTPEEIASAQSSGAAAAQGKEQRDKINVRND
DARVKEVGIEWSREMCRLMWRESVKSREERGAMEESLHRNHAAFHMCTLNLEKSVTRILH
DLSWAGPSQMTNKASTHDAAFAENTLATNGTNAADSGSARSVAKLHATLNDSLSVSAPAA
LWDEFTNGRYGDSRSPAFGEIDGYGVSLKVPPADALRVWRTPVTEGDISALFVAYLSGEI
QAIPWCDIPILNETQAIREELLSLNRAPSASLGQGDHSTIGKGWWTVGSQPAIDGVDSLE
PTFGFGPKGGYIFQKAFVEFFVDEEQMLALCRRVEESDGLVGLLAGNREGNFKTTLEPNA
VNAVTWGVFPGQEIAQSTIIEEESFKAWRDEAFEIWAEWELLFPQGSPTQRLLKSIGDNK
WLVTVIHHDFKDPGALWRFLGCGRSEHSH
>A0A4Z0YAI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caproiciproducens galactitolivorans|TrEMBL
MKISECLKSGRVTVSCELFPPKKDGELEHVREVVRDMAALKPNFMSVTYGAGGGTSENTV
RIAQEIESRGITALAHLTCVSSTKDQVARILAELKEKRIENILALRGDIPKDSDFPSPGH
YRYACELVAEIKAHGGFCIGAACYPEGHIECAHKEDDIEYLKRKVESGCDFLTTQMFFDN
NILYNFLYRILAKGINVPVVAGIMPVTNSRQIKRICALSGTVLPPRFKAIVDKFSDRPAA
MEQAGIAYATEQIVDLISNNVKNIHIYTMNKPDVAARIMGNLSEIIG
>A0A524QK18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MTEARKQSRQFTPIKSELSVSFEFFPPKTQAMEETLWQSIKRLAPIEPRFVSVTYGAGGS
TRERTHATVKRVLDETPLTPAAHLTCVDATREQVDEVARRYHEAGVRHIVALRGDAPDDQ
SRFTAHPLGYRNAADLVAGLKRVADFELTVGAYPEVHPDALSAEDDLDNLKAKLDAGASR
AITQFFFDSDVYFRFLELARAAGISAPIIPGILPVTNFAAVQRFAATCGATVPAWMAELF
EGLDDSPDTRQLVAATVAAEQCLQLKRQGVTDFHFYPLNRAELTVAICHRLGLKGAVARN
GTQTIASGV
>A0A524QDV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MRKLENVLDSGEFVLTCELNPPKGTDLVALFEKADQLKNVVDAFNLTDSHAARMAMTPLA
VAHLLVDRGLEPILQITTRDRNRIALQGDLLGADALGVHNVVFMGGDPPSTGDHPDAKPV
FDVYSSRMLQAASALQAGTDMAGNLISGKPHFCIGAVVNLGAPDLGEEIMRMGEKIEAGA
SFFQTQAVYELASFERFAQAAAQFSVPVLAGIIPLKSIKQARYMNARVPGINVPEAIIQE
IGNAGDGTAASLAIAARTIRALDGMCQGLHIMAIGWEAYIPELLSQAGVQR
>N2BA18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter bilis WiWa|TrEMBL
MLDQLITKLHSNQAFLSVEVSPSLSSTIGQSVIDELKSLKQADCFVCTDSPLARLKPSSI
LTSIKLQNALKKPVICTFSMRDRNSIALCGDILGANEFGLRSFLSLSGDGVKNGDCVGAK
GVFEESSLKLGRIIDGLNQGIAANGKVLKDSVETIYNFSVINSYANNTESLKKKMLKKLS
NSAVQGLFTQPVFSLEAARFLLESMESINKELGQNCVMILGFFPVLSYKVALFLRDKLPG
VYIPNEWVQKLEKASIKGKEVERKIGLELSNKLFKDLQTLHNKFHFMSANKPSLLREFV
>A0A350D3S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MATPVFGSLSKSFWTPSISAKNLSAGGKMKVSEALTGRKKPVLSLEILPPDKGSNVEDLY
RLIDPFLEFDPLFISVTFHQPQNGVSVENGQKIKIRRQKRPGTVAISASLKHRFGVETVP
HLICAGYNRYELEDALLELHYLGLENIFVIRGDPQPGEKEFRPEPGGPTYACELVKQIDN
LNHGYYLEGVKPAAATDFCCGVAGYPEKHPESPSLEFDLLHLEEKIEAGARFVITQLFFS
AEIYQSYLKRLKQAGISVPVLPGFKLLYNQKQLTKIPATFGVSLPPAMIEAFEACRTPEE
EKKTGLEFGLELAENLLESGAPGIHIFTMSQKDPVINLLKILFKR
>A0A3M2BJP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKVTEHLERATEPLISFEIIPPLRGGDIKSLMALIDDLVLHHPPFIDITSHAAEVIYEET
PEGIQKRIKRKRPGTLGVCALIQNKYNIDAVPHVLCHGFNRQETEDFLIELRYLGIDNVL
AIRGDDPGFKKPLAPGKSVNNYALDLIAQIAAMNRGEYLEALLDAQPSDFCIGTSGYPEK
HFEAPNLLFDIRRAKEKIEAGASYIVTQMFFNNEHFFNYVDACRAEGIEVPIIPGLKVLT
SKRQLHSIPRTFHCEIPPALSEEVERAKNAAEVREIGVEWARQQAQELLDRGVPSLHFYV
MQSSRAINQLLKRLKR
>A0A3D3PHK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacteraceae bacterium|TrEMBL
MITSQKNFSIEFFPPKTPEGAEKLRMTCAKLAELHPKYFSVTFGAGGSTQKGTLDTVLAI
RREGHEAAPHLSCVGGSRESIRAILEEYRSHGIKRLVALRGDLPSGYGGAGEFRYASELV
EFIRAESGDWFHIEVAGYPEMHPQARSPQEDVQSFARKVRAGADAAITQYFYNADAYFRF
VDEAHKAGVTVPIVAGVMPITNYAQLSRFSDMCGAEIPRWIRLKLASFGDDTDSIRAFGL
DVVTGLCERLLAGGAPGLHFYSLNQAIATTAIWKRLGASTL
>A0A0J6F1R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella pseudohinzii|TrEMBL
MTDSTSPALSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTEETVRT
LTNLGCDAAPHLSCIGASREQLRDILNHYREAGVHRVVALRGDLPSGMGGDAGELRYASD
LVRFIREETGDWFHIEVAAYPEMHPQAASPTADLDHFVAKVRAGADAAITQYFFNADAYF
DFVDRAQARGVAIPIVPGIMPITNYSQLSRFSEMCGAELPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGVPGLHFYTLNQSEATLGIWKNLQL
>A0A1C6BU87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Blautia sp|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMFGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLEEGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMVKFMNNNVAGIHVPDEMIEE
LKADKERTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A089YSM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas rhizosphaerae|TrEMBL
MSQDRPLSFEFFPTKTDAGHEKLMGVARQLAAYKPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVNVPAAPHLSCVGDSKQDLRGLLDQYKAAGIKRIVALRGDLPSGMGMSSGELRHANDL
VAFIRAETGDHFHIEVAAYPEMHPQARNFEDDLVNFARKANAGASSAITQYFFNADSYFY
FVERVQKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLSS
>A0A7X3XFF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. SB0662_bin_14|TrEMBL
MKSQVNPSAFQQGLASGQPVVTAEISPPRGGSVDHVLAMAEQLRGRVHALNVTDGSRAVM
GMSSVAVCRLLLERHLEPVLQVGCRDRNRIALQADLLGAHALGLRNVLCLTGDPVKAGDQ
PKARPVFDYEAVRLLQDVKSLNRGLDALGRPLPDGPTALFPGCAADPQSPSWSGLKSRLQ
RKKEAGARFIQTQMVTDLAALRRFCRELAAPLGLPVLAGVFLLKSGKNARFINRMVPGAS
IPDAAIARLDGARTPRAEGLRMAAEQVATALDVAQGVHIMAIKAESAIPQILDLAGVPPL
APPVVGGLGLRSLAAEPC
>A0A6M8SLD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. M31R6|TrEMBL
MKVTKHIEKAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVD
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKEGGNNYASDLVSQIYQLNNGKYLHDVMDIDNKADFCIGVAGY
PEKHLESPSLMSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREIGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLISAVDKCKNNAEIRQVGIEWAIQQSIELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A1T4XAK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. USBA 49|TrEMBL
MQIKNIYKKKKPIISFEIFPPKKESPVDTIYDTIESLKDLKPDFISVTYGAGGSTRDKTI
EIASLIKNKYYIETLAHLTCISLTEEKLQKFIEELKENNIQNIMALRGDLPQNFNEELFQ
KSQYKYASDLIKSIKKDDEICIGGACYPEGHFECSSLEKDIENLKIKVDSGADFLITQLF
FDNESFYRFIDLAYKKGINVPISAGIMPVTNKKQIERMISLSGASLPAKFSRIMAKYENN
PQALKEAGIVYATEQIIDLLSWGIDGIHLYTMNRPETVRRIIQNISNIREALEYKDNIN
>A0A445ETN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachis hypogaea|TrEMBL
MKVIEKIRAAAAADPDRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGS
TADLTLEIANKMQNMVCVETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQ
DKFVQIEGGFACARDLVKHIRAKYGDYFGITVAGYPEAHPDVIGSDGLATPEGYQNDLAY
LKSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCK
TKVSKCCCIDYRPFS
>A0A445ETR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachis hypogaea|TrEMBL
MKVIEKIRAAAAADPDRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGS
TADLTLEIANKMQNMVCVETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQ
DKFVQIEGGFACARDLVKHIRAKYGDYFGITVAGYPEAHPDVIGSDGLATPEGYQNDLAY
LKSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCK
TKIPADIFAALEPIKDNEEAVKSYGIHLGTEMCKKILAHGIKTLHMYTLNMEKSALAILM
NLGLIEETKINRSLPWRRPANVFRVREDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSR
NPSYGALTDYQFMRPRARDKKLVEEWVVPLRSIEDIYERFKQYCLGKLRSNPWSELDGLQ
PETRIINEQLEKINLKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEK
LDALVEKCKNRSSLTFMAVNKEGSWRSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFMV
WKDEAFEIWSRGWACLYPEGDASRKLVEEVGNSYFLVSLVDNDYVNGDLFAVFADF
>A0A1H2VJ27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria halocynthiae|TrEMBL
MTKPEISFEFFPPQTLEASFRLWDTVQTLAPLNPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLPVAAHLTCVDASRQETLEIADTFARAGVQDIVALRGDPPKGKDRFEPHPEGFANSV
ELISALAETEMFSIRVGAYPDIHPEAQSARSDVDWLKAKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGILPIENWKGARNFAKRCGTHIPDWVENAFEKAVRDDREDLLAT
ALCTELCSDLIEGGVDKLHFYTLNRPELTRDVCFALGITPQTELQNVA
>A0A200HAW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium sp. PE09-221|TrEMBL
MSAPDRSLIDALRSDRPTTSFEFFPPKDDEGEAQLWQTIADLEPLDPTFVSVTYGAGGTH
QDRTIRVTERIARESSMKPVGHLTLVGQSTAEIENVLKQYLAAGVDHVLVLRGDPQGGPR
APWERHPEGMDHALELVELAARLGGLTVGVAAFPEGHPDAADREACADVLVSKAEAGAEF
AITQLFFRASDYVDLVRRLDVRGCDLPVIPGIMPILNFSQVSRMAELSGAALPPEVLEQI
EPLADDRAAVRAKGIELATQLCRDVLAAGAPGLHFMTLNRSKATREIFRSLRDEGLI
>A0A1Y2I0I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catenaria anguillulae PL171|TrEMBL
MSLKIIDKLHRAESEGRCLWSFEYFPPKTAAGVENLFARMERMWSLAPAFIDVTWGAGGS
TAELTLDICTVALSALGLNVCMHLTCTNMPRTELDKALAHCKEVGIRNILALRGDPPRGQ
DRWEATEGGLNYSIDLVKYIREKHGDWFCIAVAGYPEGHLDNPDKEDDLRRLKDKVDAGA
DFIVSQMFYDCDLFIDWVKRCRAIGINCPILPGIMPIHTYNGFIRMTSLSQTKVPDFIYK
DLDPIKDDDELVKAYGVNLAAQMCTRLKEEGDILFFHFYTMNLEKSVRLILEKLEWVAPL
EESRPLPWIPSLASKRQNEAIRPVYWKNRTRSYIARTAENDEFVNGRWSSSASPAFGDVD
GYGGVFFKHSKEQARAVWGLPRTVADLANVFVGYCQGTVKFLPWSEQPLAGESMLIRDDL
ALLNKLGYLTINSQPPVNGVPSSHPVHGWGPKNGYCFQKMYIEFFLSPELFDALVAHLAE
VDPDGVITYHAVQRKGENVRFNDPDPESANALTWGVFPGKEIVQPTVTDLAAFMAWYPEA
FELFDSWANVYDKGSEERKLVEGVAGEWWLVNVVNNDFTAPKDKLIEVLKGAARRLEEQK
VAAA
>A0A5J5J1Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium rhizomatis|TrEMBL
MTGKDVPALLEAKDSIPLGTRINVTFLGNEDLEMRVSAAKTVRELGFVPVPHISARRLQS
RAQLEEFLSALQDVGATEHVFVVGGDPTTPEGPYEDSFDVIRTGLLPEYGVRHVSIAGYP
EGHPDISGEKLWKALDDKSWSLREQGLDATILTQFAFDTDPVITWIDAVRARGIDTQIRI
GTPGPAGIKRLLGFARRFGIGANAMIVKKYGFSLTNLMGTAGPDTFVTDLSALLAADPGV
GTVRLHFYTFGGLKATADWARAYAATQS
>A0A416JFN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM49-4BH|TrEMBL
MKITQLLQEDKVTLSLEVFPPKKDTAVEQVSRSVREIAALQPDFMSVTYGAGGGTSAYTV
QIAKDIKAEYNVPSMAHLTCVSSTKETVKKQLECMQEAGIENVLALRGDIPADAEFPLPD
QFHYAVELVRYIKQIAPEMCIGGACYPEGHPEAVSKAQDIQHIKEKVDAGCEFLTTQMFF
DNSIFYNYMYRLREAGVLVPVIAGIMPITRKNQVERSIQLSGSCVPARFKSIVDWFGDDP
AKMKQAGIAYATDQIIDLIANGISHIHVYTMNDPEVAAGIMNNLSAILH
>A0A6A6NK49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hevea brasiliensis|TrEMBL
MATTLALLSLVIQVLKAILGFLLCPILLHYPQKIISLCSSAIFRSEAHPDMIGSDGVATP
ENYQKDLEYFKRKIPAEVTAALEPIKDNEEAVRAYGIHLGTEVCKKILAHGIKTLHLYTL
NMEKSALAILMNLGLIDESKITRSLPWRRPTNVFVQRKMANRPKSYISRTLSWEQYPHGR
WEDSCNPSYGALTDYQFMRARARDKKLHDEWATPLNSIEDILEKFKKHCLGKLKSSPWSE
LDGLQPETKIINEQLGKINLKGFLTINSQPAVNGERSDSPSVGKLGGPGGYVYQKAYLEF
FCSTDKLQVLVDKCKSFPLITYMAVNKGGTLVSNVGTNDVNVVTWGVFPAKQIIQPTVVD
PASFNVWKDEAFEIWSRGWASLYPEDDPSRKIA
>A0A7L2HR79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sagittarius serpentarius|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYETDLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPEEIKDVIEPIKDNDAAIRNYG
VEQAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A838XVP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stappia taiwanensis|TrEMBL
MTSPDKIRRFELGNPGAVSVSFEFFPPKSDKMEAKLWSAVERLQPLDPSFVSVTYGAGGS
TRERTHRTVSRLLKETAMAPAAHLTCVGASRGEIDEIVREYADLGVRHIVALRGDPLEGI
GAVYRPREDGYAYASDLVEGIRRVADFEVSVSAYPERHPESADWSAEIDNLKRKVDAGAT
RAITQYFFDNDLFETFLEKVRAAGISIPIVPGILPITNFEQTMVFSAKCGTSIPHWLARR
FAGLEQDSETRKLVASAVACEQVLDLVDRGITDFHFYTMNRADLTFAICHMLGVRPATSE
QQAA
>A7ZUG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O139:H28 (strain E24377A / ETEC)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4Q9N0L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dichomitus squalens|TrEMBL
MVGKGPSSCPPCVMKISHKIEQAAKEDRIWWSFEYFPPRTAQGLQNLLDRIERMRALGPE
FVDITWNAGGRSSELTSELVKTCQKLIGIETCMHLTCTGMPKEKVDTALREAKQHGCRNV
LALRGDPPVGKEWEAVEGGFSYGVDLVRYIRAEYDDYFDVAVAGYPQTQTLPPAEAAREM
QYLKDKVDAGANFIFTQMFYDIDMFVAWVKAARAAGITVPIVPGIMPIQTWNGFQKATQL
AKITVPQFFLDELEPHKNNDEKVRELGTKLVAKMCRQILAADIGIKGLHFYTMNLEKGCR
LLLEELNLVPRVEVVKPLPWRQSLTPNRRTENIRPIFWANRTRSYLSRTENWDEYPNGRF
GDSRSPAYGELDGYGIWIKQSKEDALKLWDTPTTVEQIRALFTKFCLGQLSALPWSDTAP
SSETTIIAQQLAKLNELGFLTINSQPAVDGARSDDRVHGWGPANGYVYQKAYLEFFVPPE
LLELLIPHIERDINITYYVINARGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAISFM
AWKDEAYELGRQWAQFYEPDSSSRQLIDEMMSTYYLVNVVHNDYKKPDAIFEPFFKAGAE
YAAKHTATNGTANGTAN
>A0A0F1AX69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sichuanensis|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A511X200|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halolactibacillus alkaliphilus|TrEMBL
MKTSELFQRKKVLSFEIFPPKQTENLAAIYQTVNALKELAPDFISVTFGALGTKNNQRTL
DIASTVKHTYGVESVAHLPSSQFTKRDVQDLLTRFKQLGIDNILALRGDDITEHKEKKDF
HYASDLIEYIKSEGDFNIIGACYPEGHIESVSILDDVRHLKRKVDSGCDQLISQLFFDND
YFYTFKERTELVGIDVPIQAGIMPVVNKRQIEKMVKMCGVNVPKKFLKMMERYEHHPEAM
RDAGIAYAIDQIVDLITQGADGIHLYTMNNPYIAHRIYQAVNQLLIAS
>A0A2S6Z394|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. populi|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDT
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A2W5CQK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas hengshuiensis|TrEMBL
MNLSVPQLEEARRALDAPLFADLAGDAEVSFEFFPPKTEKMEEALWETVKTLAPFGPRFV
SVTYGAGGTTRERTHATVARIQRETPIAAAAHLTCVEASKAEIAEIADAYWAVGVRHIVA
LRGDAPGADAFVPHPDGYTNAADLTAGLKALHPFEISVAAYPECHPNSRDEADDLDNLKR
KLDAGAMRGITQFFFEPETFFRFRDRAAAA
>A0A415ENA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidaminococcus sp. AM05-11|TrEMBL
MKIVDLLKSPKICVSCELFPPKKGNDLKNALNIVHTIADHGVDYMSVTYGAGGSAVGKSV
ALVGEIERCGVPALAHLTCVGATEDRIEGVLDSLKQVNVENVLALRGDKPQGMDAMPEGA
YAHASDLVRKIKSYGDFCVGGTTYPEGHPEAASLDEDLEHTKIKVEAGCDFLVTQMFFEN
SMFYNFMYRLLAKGIQVPVVAGIMPVTNVKQIERIFTLSGTPVPASLRAMVERFADHPEA
LKQAGMAYAIGQIVDLIANGFTNIHIYTMNKPEIIGGIRDNLSEIIKL
>A0A562IQC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter roseus|TrEMBL
MNRSLPRNPETRAALRRTFETLGYEVIPFKKTGDDVQEHVPTDVRLTVTASPAKGMGATV
ELAVRLTQAGYTVAPHFSAQQIHDRAHLTDVIAQVREAGITEVFVVGGDPTDTPTEFKDA
HALLLAMKEIGHPFTEVGIGGHPEGHPSVSDDVLYGALADKAPFAQHITTQICFDTGKIL
GWARELRRRGVDLPIHIGIPGAVTRQKLLRVSNGLGVGESAKFLKKQQNLLWRFFVPGGY
SPDGIIRGLAPEIGASDQRIEKFHVFTFNDLAPTEAWRQQMLSRLAEQ
>A0A1C9WPS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. U41|TrEMBL
MFPTRLEIIPSEGIVEKVTAAVPLGTTLTITCLPQHGVGRTMRAAVRLAELGYPVVPHLA
ARALQDRPQLVGILRECDAAGIREVFAIGGDSPRAAGSYGTAGELMEDIAQYSGGGISIG
VAGYPEGHPSVVGIELLDALLAKQHLASRVVTQMCFSAPKIVDYVGLLRREGVELPVWAG
VAGAVPRTRLVALGTQIGVGASLKFLSRKGPLARRLLSGERYQPATLISELAEHPDRVAG
IHFYTFNHLNAVAGEPTPPSGPATTELVSVPGGAE
>A0A455STN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosporothrix sp. COM3|TrEMBL
MRTQHPFLERLQRGPILCDGGMGTQIYARGISFERCFDQLNLTDPELIKAIHLDYVAAGA
EIIETNTFGANRYRLQEHGLEHKVHDINRAGAKLAREVRDMSEQPIFLAGNIGPLGVRLT
PLGTVKQQEARDAFREQAEALLESGVDLLILETISDLGEMREALQAIRPITDVPIAALMT
FGEDNTVTSGEDPHTVARVMSELGADLVGVNCALGPAGTLSVIERMQDEQHAFHLAAQPN
AGLPRRVGNRFIYISSPDYFAEYTRHFLQAGVQLVGGCCGTTPQHIAAMSKVLREFAPEL
QQRPKPVKEQAKIELVYDKRVQQQPPRGTKAPSTRLAQLLAAGRFAVSAEMRPPRSIKFT
RFLQNAEYLRDAGVDVINIPDNAMARVRMSNVAAARLIQQFVGTETIIHFTPRDRNLMAM
QSDLIGAHATGIRNVLAVTGDPPTHGDFPGATGIWDVDSIGLITILNNLNRAIDGTGRKL
ASAASFFIGCAATPSATDLDLEIERLQRKVEAGANFIMTQPVYDPETLLHFFDLYKQRYG
ALQIPILVGLQPLHSYQQAEKFHNEVPGIVIPDTVRKRLKEAGERGIEAGLEIIKELLSA
IYPHIHGVYIMPLDRYDLVRELLPYIRSLTEPTSDSQHS
>A0A1U7NDW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ileibacterium valens|TrEMBL
MGTLFAQNTSKPSTKTEAANRMDPDTIVQIHKDYIQAGCKAIKTNTYSLADELAQNLSGQ
KEEYISDLIQAAVFNARQAIKESDCHEEIYVFADLGPISAEAKSDSLLIYQKLISIFLEQ
GVRNFLMETLPDTEWIDEIADWLKNTCSDSFLLVSIACAADGITRSGKSGIEQIKILDQM
ESVDAVGFNCMCGPSHLLNLVKDLPELHKPLSVMPNAGYPSILSRRTVYDGTPDYFASGM
ISLIHHGAVILGGCCGTTPEHISALFKELEQEKKKILEDVDHLNKCSAQETEKKVHSDED
PELGIPNPNSFKDGKEPGILLKNHAAKRKSYLVELDPPANDSISFFLEGVSRLKHSGADM
VTIADNPIGRPRADSSILACKIKREAGIEVLPHMTCRDRNLNAIKALLLGLSIEDVHHVL
LVTGDPLPSDLRQEVRAVYSFNSRMLAGFVKTLGESKTCTPFHMYGALDINARNFDVQIR
IAKEKEANGMEGFLTQPAFSDRAISNLKRARKELKGLIMGGLMPIVSYKNALFLANEISG
MDIPESIIEKYKVLSREEAEQLALSIVLKTADQMGDDVDGYYIMTPFKRVSLSQKIVEQI
RKMEEEKLN
>A0A7J6E3T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cannabis sativa|TrEMBL
MGFVGSWYDEDGDEFVGSTGTIFCLRDDDSPQSTGNHINGQDCKEGEPEGRKEGRKKMKV
IDKIRCEANNDNVVFSFEFFPPKTEEGVENLFERMERMVAHNPAFCDITWGAGGSTADLT
LDIANRMQNTVCVESMMHLTCTNMPLDKIDHALSTIKSNGLQNVLALRGDPPHGQDKFVQ
IQGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDAIGPDGLASPEAYQVDLAYLKSKV
DAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFIRMTGFCKTRIPS
EVTAALEPIKDNDEAVRAYGIHLGTEMCKKILGSGIKTLHLYTLNMEKSALAILTNLGLI
EERKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTTGWDQYPQGRWGDSRNPAYG
ALTDYQFMRPRSRDKKLVEEWSIPLKSVEDIHEQFKKLCLGKLKSSPWSELDGLQPETKI
INEQLVKINGKGFLTVNSQPAVNGERSDSPVVGWGGPGGYVYQKAYLEFFCTKDLLDALV
EKCSRGFSSFTYMAVNKQGHWLANVDQTFVNAVTWGVFPGKEIIQPTVVDPASFTVWKDE
AFEIWSRGWARLYPEVDPSRKVLEEVENSYFLVSLVDNDYIHGDLFAVFNEF
>A0A4V0X2S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterales bacterium|TrEMBL
MNKDLSISFEFFPAKDETGHNNLWQSLKKLEQFSPKFFSVTFGAGGGERDKSDFLVKKIK
NQSTIPAAGHLTCVDMSKDEVNSVALSWLKNGINKIVALRGDVRTKNSKYVPHKEGYINA
ADMVKGLKKLGNFEIAIAGYPEKHPESENEVKDLENLKNKVDQGADKIITQFFFNYEKFL
KFRDRAVSLGIKIPIIPGILPIDNFEKVKNFSSKCGTTIPNWIEKEFAGLETDSEIQKIV
GASIACDLVKKLYAEGVDEFHFYTLNKYELSYAVCKRLIGDKIVTQNKQQKELYA
>A0A173LK77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia timorensis|TrEMBL
MTAGNAHDSHTTAHDGVIARMSASTTARIPFSVEFYPPRDEAAEERLWRAASVFEQLGAA
FVSVTYGAGGSTRDRTLRITRDVANNTALLPIAHLTAVGHTVSELDALVDEYAKAGVHNI
LALRGDPPGDPLGEWTQHPGGLRYADELVRLIGEKDSFEVGVASFPEGHYRASTLDVDTE
VLVTKLRSGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIIPGLMPVTSLRSVRRML
ELSGSKLPADFESRLTRAAGSGETEDRAAVREVGIEFATNLCERLIREGAPCLHFNTLNF
SRATQEVLANLGMAPEVGAHGGVVLA
>A0A1C0TP78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas luteoviolacea|TrEMBL
MALSLQEKILDPNQGVYLIGTTPPKLGTDKEQVQAIATKLLNRLHEIEYDGVVIYDIQDE
SSRTEVTRPFPFKQTVDPCEYSQVVSQLSNLDVITYKSVAQRDHSEFTQWLHKTKQDFGL
SNLVLVGSPSSKGDIKLSLPDAYQTLRDHQEDFFLGGVTIAERHSSKRNEHERLIDKTAQ
GCEFFISQAVYDAQATIDLLTSYARTCRQQGIEPQRIILTFTPCGGQKTLEFMQWLGISV
PEATKWRMLDAENTLKESIKICRENLDLILRSCAQLDVPLGLNIESLTNRKEEIDASINL
YRLLKATMELKLAEKQIA
>A0A0K2NXA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter dublinensis subsp. dublinensis LMG 23823|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVELKT
A
>A0A1H2U7K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sanguinis|TrEMBL
MSVRRTVPAVSFEFFPPKTLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVT
ALATHYGLNVAAHLTCVEATRAETMQIVDDYAAAGVREIVALRGDAPQGAAAWTPHPEGF
ASSVELIEAIAARGGFTIRCGAYPEPHPDSADSAADVAFLKRKVDAGATSAITQFFFDPD
TFFRFRDACAAAGIAAPVIPGILPIQSWAGAKRFAARCGTSVPAWAEDAFARAGKPGEAA
LARDIAVELCTRLIEGGVDRLHFYTLNRPELTAEVCAALGIEATEAAA
>A0A2P5A0Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma gamsii|TrEMBL
MMDKITDKIAALPADGEYFSLEFFPPKTQMGFSNLRVRLQRMERALRPLFVNVTWGAGGS
TAQKSIELAELCQRELGLTTCLHLTCTNMSQAMVDQALEDARALGIRNILALRGDPPRAE
YRDADEPTGSEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPYL
VDKVQAGADFIMTQLFFDIKAYEKFETTLRDHPSGAFKTIPILPGLMPIQSYAMIKRTAK
LSHAEMPEEIMARLNAVKGDDEKVKMVGVDILSELIEQIREIKSRTPGPRGFHFYTLNLE
KSISFILERTKLIPDVPDDEEAVVDEPVPAAVTGQRSIPRISVNGNVPPRQSRSHSRTAR
RQSSVGSDPFNRVIVGRAAAHPEWEATSTEAGLPAESLNTRANTLAISEGEGALGREATW
DDFPNGRFGDARSPAYGEIDGYGVSIHMSVTQAVSLWGHPKTSSDINDIFVRHIRGEISA
IPWSEEDLLPESNIIKSSLEAMNKKGWWTVASQPAVNGLPSNHATFGWGPASGFVFQKSF
VEFFIPSADWKILYDKLTSEEHEELVCFYASNANGDFVSSDSTGGTGRVTVNASTNAVTW
GVFPGKEIVTPTIIEEVSFRAWSEEAFDIWAEWAKVYGRGSDSEKLLNEIGQDRWLVNII
HHDYVDTEALWRLLTN
>A0A1H7CS22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionispira arboris|TrEMBL
MPRISIELVPRGEAAIREELELLKNNFTCIDLINVPELLRYELHSWEGATVAKEFYREAM
PHIRAIDIDLDKPLPMASYLVEHKISEVLVITGDPPQDMGRTIYPTVSTDVIRKFRDELP
HIKVYAGLDQYRSSMRQEEYNIRRKIQAGAAGFFTQPFFDLRYLEIYAEILAGVEVYWGV
SPVLSERSVNYWESKNNVIFPKAFQPTLEWNIDFARQALAFVKKQDANIYLMPIKTNLLP
YLRGAFAK
>A0A1Y4S3E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor sp. An135|TrEMBL
MKIIDILRQDRPTLSFEVFPPKTSDSYESVAQATQEIAALRPDFMSVTYGAGGGTSSYTI
GIAAGISQKYGVDTLAHLSCVSSTREHVHKMLSEMKAQGIQNVLALRGDIPAGGAPAHDY
QYAAQLVRDIKASGDFCVGGACYPEGHPEAPTKNADIDHLKEKMEAGCEFFTTQMFFDNN
ILYNFLYRIREKGITVPVVAGIMPVTNGKQIARICKLSGTYLPEKFKAIVDRFGDNPAAM
RQAGIAYATNQIIDLIANGVEHIHIYSMNKPEIAAGIQASLSEVLKP
>A0A239E0L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus saharensis|TrEMBL
MSAEGGVVLDARVALEAALRGASYEVLPLRGTEEAVVEHVPRSVPLTVTVTQSRGLTPTL
DLAERLAGHGFAVSPHLAARLVRDATHLSDVVAHLHAAGVDGVFVVGGDAPEPAGTFTDA
LGLLEALETAGHSFRHVGIGGYPEGHGHISPALIERALERKAPHAGEVITQLCFSAAAIT
AWARQVALRGVDLPIRIGLPGAVTRQKLVRISAGLGLGQSARFLSKQHRLIWRFLLPHGY
RPDRLVDGLAPALGQPGHHLRGFHFSTFNEVARTEAWRQDRLARLSGDGTG
>A0A1V4WMP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdus sp. PtaB.Bin006|TrEMBL
MKPDSKLAVTMGGKEFIFTAEYLPVAGTEVTIDPKLFGSNVIAVNVADNHHGVSMSSLAA
SLALSRGGIEPVFQIITRDRNRIALQSDLLGAAYLGMKNVLCLSGFHQTLIGCSESANVF
DIDSVQLIDIVKKMNNGQLLDGTKIQGNFAMLIGAAANPNLKPLELNILRLSKKIAAGAD
FIQTQPVFDVDDFKVWLEAVRNAGLTDKTAILAGVMPLKGAAQAKGLADTYTDYIIPEAI
INRLDTAGGIEAQEKEGVKITAEIINKLRDLPGLKGVHILSGGNESTVSELSGLSQ
>C6XUY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3)|TrEMBL
MKIIDHINNAKGKTLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNRYKVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDSSFIPTPNGHAYASELLQHVVDMNNGKYLHDDMESAEKTDFCIGVAGY
PEKHFESPNLDTDFRYLKHKVDTGADFIVTQMFFDNKKYKAFVDKCRENGIHVPIIPGLK
PITSSKQLISLPKIFHLDIPIELSEAVHGCKSEKEVKEVGIEWMINQCNELKAMGAPVLH
FYTMGNPEPTKKIAQAVF
>A0A0R2T629|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium BACL7 MAG-121220-bin83|TrEMBL
MKVIDHIHAAKGKTLFSFEILPPLKGTRIDDLFGTIERLVEFGPKFIDVTSHREEFVYKK
RENGLLEKVHTRKRPGTVGICAAIQNQFKVDTVPHVICGGFSREETEYALIDLHFLGIDN
VMVLRGDALRADGAFKPEPNGHAFAIDLLKQVVDLNHGRYLHDEVENNNPSNFCVGVAGY
PEKHFEAPSLRTDIKYLKAKVEAGAEYIVTQMFFDNAYYFAFVDKCRAAGIEVPIIPGLK
PIATGGQLATIPRNFHLNLPDDLVDAVEAAKTPAEVKQVGIEWCIEQSKELMQKGVPVLH
YYTMGKADATEQIASVLF
>A0A560K3X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sacchari|TrEMBL
MTDLTTPATADRQDGHLKRPAISFEFFPPKSEEMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPAG
GIGTPYSSHPDGYQSSAELVAGIKKRHADIEVSVSAYPEKHPEARDFDADLDTLKAKVDA
GATRAITQVFFDNDFYFRYLDRVRARGIDIPVVPGIMPMHNFKQARNFVTRNGTTVPDWL
AAKFEGLDNDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A1V5GYR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium ADurb.BinA184|TrEMBL
MARRITRKLSAAPLEPEGPAQLKLSFSTDNPLGENLRRGEFSVLVEVNAPPREQPFEPAV
AVAERMAREIRDVPWATGMAVTDRLRSEDCYDAASLVGLLATASGKPVLMHLSGKGSDKA
RVQEMLARGLSAGARSLLAVTGDRSDKHPAPHGLARNPPHPVGYFDSVETLHTAAASGHG
FLLGAGVNPFKYNVADQCLQRYKMVRKLATGAQFLVTHAGWDMKKLQELQWFLQMRQVDV
PVIARVALLSGDQIRALQDDVFPGVFLSRTFASVLQRESEINDTQSLAAQLQRLGLQVAG
CRLLGYSGVQVVGVRDERTLAMVLKRIDEALAAFTSYPEWVAAWTEHHMSMEFSPLAGVY
YGFPNLLTPQHQFYEAGATVVSRALPLPSRGDRRRSTALRLCLSRVAPEFVKKAGVGVLA
RGWTARRDRLAYTFHLSPEACPKRLVFGACGGAGADGTCEFGGARCFFHRVLAIAARRGR
LDRLEQGLTGD
>A0A4Z0BIE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramlibacter humi|TrEMBL
MSTLPVSLEFFPPKTEEGAEKLRGARQKLYALKPEFCSVTFGAGGSTQEGTLASVREIMA
EGVSAAPHLSCIGQTRDSIRERLVAYSTAGVKRIVTLRGDLPSGYGLGGEFRYASDLVAF
IRAETGRQFTLEVAAYPEVHPQARSPQADLEAFIAKVEAGADSGITQYFFNADSYLRFVD
ELRKRNVQVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDSASIKSFGLDV
VTALCERLRAEGAPGLHFYTMNQAQATLEICRRLGA
>A0A242XJA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar guiyangiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGANVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTEKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAALNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLKQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A250JU10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus macrosporus DSM 14697|TrEMBL
MKIRNRLNPSDPCFSFEFFPPRTDEGEANLLKALEDLAALQPGFVSVTEGAGGSTRTKTV
ELVLRIKQETGIEAMAHLTCGGHTPAELRAVLERLSAAKVDNILVLRGDPPKGQAAFEPA
PGGFRYAAEMVRFIREEDFNFCLGGACYPEGHVETPSRDDDLRHLKAKVDAGLDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQIQRFTRLCGATVPMRLALQLERVKD
NPEAMAQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRARS
>A0A1G9VEX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides szechwanensis|TrEMBL
MAELIHEGRRSFSFEFFPPRDEAGEAQLWQAIQDLEPYEPTFVSVTYGAGGSSRDTTIRV
TSRIARETSMTPMAHLTCVGHTREELEHILDSYIEAGVHHVMALRGDPSEGPRAAWTPTE
GGLNYATELVEMAHSRGDFRIGVAAFPEGHPSAESLDQDAEVLVAKARAGAEFAVTQMFF
RSEDYFGLVERVRAHGVDMPILPGIMPILNLAAIRRQGELIGTDVPDDIVARIAAKDGDP
VAMRAEGIAIAGELCEELLAGGAPGLHFYTLNRSKATREIFEHLKITV
>A0A0M0LHL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia koreensis|TrEMBL
MGLLTDLQNKILIGDGATGTLLYAHGVDSCFEELNVTKSEEIQRIHEAYIQAGSDVIQTN
TYGANYQKLARYGLEESVKDINVAATKLARKAAGDKYVVGTIGGIRSFRKSVLTIDEIKR
SVREQLFWLLQGDIDGLLFETYYDFEELKTVLEIARKETNLPIITHASLHEVGVLQDGTH
LNDAFKQLESLGADLVGLNCRLGPYHMIESLTEVDLPEKAFLSAYPNASLPDYQDGRLVY
ETDEDYFYQTAKAFREQGVRLIGGCCGTTPAHIEAIASAVKGLPPVTEKLVKKRPLIIIE
DHGEPVEPHLHNLVQERRSVIVELDPPKKLGASEFLRGAQALKDVGVDAITLADNSLASP
RISNLAMATLLQSDIKARPLVHITCRDRNLIGLQSHLMGLHTLGINQVLAVTGDPSKIGD
FPGATSVYDLSSFDLISLIQQFNEGMSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRLE
KKIDCGAHYFITQPLYSKKQILDVYEATRHLKAPIYIGIMPLTSAKNARFIHHEVPGIKL
SDEILAAMEYAGDDRSQGEAEGLAIAKDLIDTAYELFNGIYLITPFMRYEMTAQLTSYIH
QKQPVTTERKM
>A0A068STL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neorhizobium galegae bv. orientalis str. HAMBI 540|TrEMBL
MTADSETFSVSFEFFPPKSDEMEGQLWDTVDELALWDPRFVSVTYGAGGSTKAPTINTVR
RLVGETSLVTAAHLTCVDATHEETHSVVSEYRAAGIRHIVALRGDPASGVGTEYRPHPQG
YANAADLVRGLTELGGFDISVSAYPEKHPESADLGADIEMLKRKADAGAARALTQFFFDN
DVFERYLEKVRAAGIPIPIVPGIMPIQNLTQLKRFAGRCGSSVPSFLDARFEGLDDKPED
RAKVAADIAAEQIEDLIRRGLGDFHIYTMNRAPLVSAVLQRLGRRQIRTPRIAAA
>A0A182EIG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Onchocerca ochengi|TrEMBL
XNIHSETSSTSVAAGCLDYCGMDTVLHITCCPYTKEQSIRHLEQSKALGLKNILALRGDL
PRQDENPVLYKYRALDLIRWIKEEYKDYFTIACSGYPAGHPEAPSYRADLLYLKAKVDAG
ADFIISQIIFDGQVFEKFLRDCREIGITVPIIPGILPIQSYESIRRIAELSQLIIPDSIL
ASLEPIKNDDDAVRNFGIRYAVDLCQTLFTNGSATSIHLFTLNREASSREILQQLGLWSR
SPVRALPWRSFGENHPVRCKEDVRPIFWSLRPKSYVFRTREWDEFPNGRWGNSSSPAFND
LKDYYLFYLKGQPTKVEQLRMYGERLETLADVQKVFINFIAQNINENGVKVNQLPWNEQY
DGIRAETSLIKDQLLWCNSNGFLTINSQPSVNGAPSTDPFVGWGKPGGYCYQKAYLEFFT
SQANAEVLWNLLPSYSRLNCHIVNHDATIDWTNTETTMPIAVTWGVFPGSEIAQPTVVDP
LSFRVWKDEAFDAWLNWSSIYAEGTSSRCLLEKIYNEYCLVTLVDNDYPKSTIIFDCLAQ
LVSKNFGEIL
>A0A1F9Z4Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon RBG_16_67_27|TrEMBL
MSAPHPAYGRFEQALRSGRPVVTCEVRSADGADPAAVRKRARLVRDWVDAVNVPDNTGGV
VHASPWASCAILAQEGIDPIVHMTCRDRNRMALQSDLLGANLLGIRNVLCLTGDHMIHGD
QPETKPVYDVDSIQLVAIATKLAREGKYLSGREVKPPPNLFPGAAANPFAPPYEYRPLRV
GKKVDAGARFIQTQIVYNVDRFEEFMARVRDLGIDRRVPILAGVAPIRSVKAAQFMRDQV
PGMEVPDPLIRRMAAAGDAKARREEEGIRICVEIIERLKKIPGLAGFHLMPIEWESAVAE
ICRQSGLRPATSPPAAGSSASPVSPLLNP
>A0A0A0HKC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius mucosus DSM 17069|TrEMBL
MKTPRISFEFFPPKTLEASFRLWETIHTLAPLDPRFVSVTYGAGGTTRELTREAVGTLHK
ATGLNVAAHLTCVDASRAETLEIAEQFAAAGVSEIVALRGDPPKGANGFVPHPQGFANSC
DLISALADTGKFTIRVGAYPEKHPEAADRRADIDWLKRKIDAGASEAITQFFFEAETFFR
FRDACAAAGINAPIIPGILPIENWVGARKFALSCGTQVPAWLDEAFDKAIRDNRHDLLAT
ALCTELCSDLLEGGVEDLHFYTLNRPELTRDVCHALGVTPKVTLRDVA
>A0A0C1RKS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylacidiphilum kamchatkense Kam1|TrEMBL
MATLIDRLNESLLIGDGALGTYLYSLGIPRGYCIEELSLSHPNLLEKVHRDYIDAGAKII
RTNTAEANAYHLSFFKLEKKLKEIVGRSVQLARKALGSREGWIAGTVGPIWTKPTESPID
MATRQSLYEELIASLIEEGVDLLFFETFTELSELLLVLDIARKKGADKLFAFIASFEEGK
LSSGETLGEAFSKLRHAGATLVGINGACGVQASIHLLEEIELKAGEFLGAYPNAGKPEFY
DGTFTYSASPSYFGENVARFAEEGVCLLGGDYGTEPAHIAAMAQRAATIKPLKEKPPKRR
PRYLVSEQEVLPQIEPSLLDLLALKPVFMVEYDSPKTLAIGKFLEGVKAIEKAGADAITL
ADNSLAILRISNFAAAIHVRRVSKMIPILHIACRDRNLLGLQSELMGLGTLGFRHILALT
GDPAKSGDHPGATSVYDLNSIGLIRLLASLNRGFNAAGKDLKGKTDFIIGCAFNPNTSQF
EAQVKKLEAKLAAGAQFVMTQPIFDIQLIKKTYNYLKPLGIPVFIGLMPLLNYRNAEFLH
NEVPGISIPEAVREKLKAVDGEKAMEVGVGFAQVLGEEILSLFKGIYLITPFLRYDISVR
LLELLFSRKKS
>A0A1I2RCG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ligilactobacillus ruminis DSM 20403 = NBRC 102161|TrEMBL
MITQMFFDNESFYRFRECCELADINTPIVAGIHLYTMNDAETAKYIWQATRSLFENGRRV
HQV
>A0A3S7D5U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. CFNIH10|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGSGKPDMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGI
>A0A560SXT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SJZ103|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISNMCEKLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1G1E8V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium GWA2_42_11|TrEMBL
MKIARLLKNKRQIFSFEFFPPKTDEGEKRLFETIENLKELGPSFVSVTYGAGGSTRDKTA
GWVIRIKNELDIEAMAHLTCTGTSCENLKRILDKLQENGIENILALRGDKPQDTNSIAQM
PQCYNHTNELIQYIHDNYDFCIGAAAFPEGHTESPSLEKDTYYLNMKSMAGAEFFITQLF
FDNRLYFDLLDRASKIGINKPIIPGIMPITSADQVERFTSLCGAAIPSDLRERLHEIRND
RRAVMELGIGYATKQCQDLLSKGAPGIHFYTLNRSSATRTILKNLL
>A0A6I1KJ63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium|TrEMBL
MLQQKLDSGGFAITAEVCPPKGSDCGEFLEKSRALQGCVDAINVTDNQGANMRISPLAAA
SLLTREGIEPIFQITCRDRNRLALQSDLLGAAALGIRNILALTGDHISFGDHQNAKPVFD
LDSVQLLQTIAALSEGKDLSGNALQGKPSFYAGAAAAPEAEPFPLTLYKLEKKAAAGARF
FQTQAVFDPEKLRFFSETVRPFNVKIIAGIFLLKSAGMARYVNRHIPGLKVPSPLIEELE
GAADQLAKGTEIAGRLAAQARLHCDGVHIMAMGREDLIPEILKAVKREL
>A0A240AFK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mammaliicoccus stepanovicii|TrEMBL
MNLTEALKNQILVADGAIGTILYSEGLDTCPESYNLTHPKKIEHIHRSYIEAGADVIQTN
TYGANFEKLQDYHLEHRVKDIHKAAVQIAKRASNKNTYILGTVGGFRNIKKSDLSIESIQ
YHTEIQIETLINEGVDGILFETYYDLDELLTVLRHTRAKYDIPIIAQLTASNTNYLRNGT
LIPEALESLLKAGADVVGLNCHHGPYHMLKTFKHIDIPNHAYLSCYPNASLLDLEENELK
YSNNAEYFSDAAKELVNQGVRLIGGCCGTTPEHINKIKQITKNLKPITHKNVVPIKTKQY
KKQNKIEPSIKELVTNRPTVIVELDTPKHLDTSQFFEGIQALEDAEVDAVTIADNSLASV
RISNIAAASAIKQHYKIRPLVHLACRDRNLIGLQSHLMGLSLLGINDILAITGDPSKVGD
FPGASSVFDVNSNGLAEIITQFNQGINADGDTLRSNTNFSVAGAFNPNVRRLEPAVKRLE
KKIESGMEYFITQPVYEPEKVKEIYEATKHIDAPIFIGVMPITNYNNALFLHNEVPGIKL
SESVLNAFEKVKDDRDATRRLSMSMSKQLIDAIHQYFNGLYLVTPFLKYDMTVELAKYSK
SITGTQIKEAIL
>A0A2Z5QW31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia aeria|TrEMBL
MHKEFGVPSGTLLSGEHEGMKMTTVHPALSYELYPPRSHASCDSLLKTITELEQTNPDYV
SVTYSGDAQRRQKTLALLDHLVHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLA
LRGDIPPENTRPLELPFARYLVELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQ
DIEILLSKQRAGADFAITQVFFETERYSGLVDAARLAGVEIPIIPGIMPVTSLTRLTKLC
ELAGLEVPRELAHRLETASEPREMHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLD
VLEELDVPRYSNRFKLP
>A0A4R7ZPI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2570|TrEMBL
MRGFELVCEVEPPTRPDLKKVRHQIGVMSPIADAFLIPDNHIGRATVSSVAVANEVQAMG
SRGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDDPAEGARTSQLTVRTMIEQARE
TSYPGCNPFQVGAATRLRTVPRWKAEADFLYVQVSYDLDELLRWRESVDLDIPVYAGVMV
LASAKMAHNLAALPQLSIPDALIDAVERDRDAGVDHACEQILKIRDSGAFDGVHLIPVSR
YRQVAARLEREL
>A0A1A0UBK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. 852014-50255_SCH5639931|TrEMBL
MSAGLECPKRMEFGPCGGVRPDGQCEMRPGPCAFDGVVAWSGHQHAARPARVPLLLTDFS
CTPFDRRDVAATAAVLAPGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDRN
RVVLEQELRGLLSINVETVLCVTGDGRGYDVRPEVTQTFDLDGPRLVSLAASTGVVAAVP
ETPTAPPVAARPARLVEKQRAGASLAVLNHVPRPEMVADFVTVARAAGLAIPVIAAVAVF
TDSVSAAVLQGLPGLELDQTVTERVLGALDPVSAGIEAAVAEARALLSIEGVEGVNVSGL
ASASGGRMGAEIKAEVGRRIRGEGRR
>T5I192|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus erythropolis DN1|TrEMBL
MTFDPVRGRSSEGWATRTPSIVDRIASSTGSRIPFSVEFSPPRDADAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSTEELRAMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPEGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
YDTKYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVSAYDAEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGPDENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTPDTSVGTAQAV
>A0A1Y1USX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kockovaella imperatae|TrEMBL
MPHLTELIQAANGPFHTLEFFPPRTEPGLVNLLDRIRRFTSGSAPPLAVSITWGAGGSTA
ERSLDLAAQVVELGVEVILHLTCTNMPRDKVDMALTRARGLGIHNILALRGDPPRPEEYA
LTPPSEPDFFQHADDLVRYIRAEHGDYFCIGVAGYPTPHQDSQSMEDDLKWFKLKCDAGA
DFIVTQLFYDVHGFESWVRRCRDAGITQPIIPGIMPIQNFSSFRRLVNLTGCPVPNSILS
HLYPIKTDDAAVKQYGARLATQMVSRLMASGLVQGVHFCTLNLEKSVRTIVENLGWAAPA
APSPEHHNRVIEEATGQLSNLSISPSEASHLAQIGLHRSPQTKPLNPPNLEDSWDEYPNG
RFTDVRSPAYGEIDGWGSGIKTTSARALEAWGTPTCHNDIGNLFTAYINNDPSLPSPPTT
PFSDLPLSAESSSIIPHLLKLNAKRYYTVGSQPSVDAAASEDPIHGWGPRGGYVFQKSFV
EFFVPLSEVQRLEASVSKRITMYAANKKGEFRTNTEPGAVNAVTWGVFPGQEIVQSTIIE
ATSFMAWKEEAFDIWTDWSMLYPRGSEARNLLDTIASEWWLVSLIHHDYKDAAALWRFLE
TE
>A0A412B193|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] leptum|TrEMBL
MPGASEQRCGHRYHFRFSYGPGQAGSSGVRSQASAGNRDGGAASFLLPRPECQRSAGHAP
RSQCENIRTILAVTGDHVPELNRGYIKPVFNVTSAKLMEMISQMNQDVFADSPFTIGGAF
NPNVANPKAELARLEKKLKAGAVFFLTQPIFDEGRISTVKEARAMGAKMLLGIMPLISYR
NAVYMNNEVPGIQIPTAYVNRFSPEMSREEAQRTGVEIALEIAESLRPHADGFYFMTPFN
RAEIVAELIEKCRKM
>A0A7G3ZN98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Torulaspora globosa|TrEMBL
MKITEKLQKQREKSSKPTFSYEYFVPKTTQGVQNLYDRMDRMYESSLPQFIDITWNAGGG
VLSRLSTDLVSTAQSVLGLETCMHLTCTNMPVSRIDEALQSAYDSGCQNILALRGDPPVN
SEWTQVQGGFKYAKDLVKYIRAKYRDHFDIGVAGYPEGHPGDDTDDSELIDYLKQKVDAG
ASFVITQMFYDADIFIKWCKKVREAGIDIPIIPGIMPITTYAAFLRRAQWCDIHIPDEFM
KQLEPIKDDDQQVRETGTSLVVDMCQRILDSGYVTHLHLYTMNLEKAPLMILERMNLLPD
QEELDGENTLAMLPWRKSLNPQRRNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGDS
SSPAFGDLDLCGSSLIRQSGKKSLELWSTPKTAEDVAQLVVDFLERKVSCLPWSDMPLNH
EVDAILDDLIQLNKKQIITINSQTQLNGVKSSDPVFGWGPKDGYVYQKQYLEFLLPRSKA
QRLHDALKDDVILTYFAVDDEGNLSTNHPDGCRANSVTWGIFPGREVLQPTIVEKVSFLA
WKEEFFHILKEWRLNFQNHQIGDSADLLTHLISDYVLVNIVDNDFISQDNKIFALLNTI
>A0A849ITD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTVMDHLRGPWPSFSLELWPPRTPQASARLSTAIPQLVDLKPTFVSITYGAGGSTRERTH
ELVVELASTQGILPFAHLSCAAHSVAELREILARYLRAGVTNIVALRGDPPLASDLPLPD
GELLFASQLVDLIKGCGPFTVAVAAHPEGHPQSKDLSEDLHHFCEKLDKADFAITQFFFR
AETYFEFIDKVRSQNIDKPILPGIIAPTSISSLVKMSELSGAVIPQALRDALMGASSDPH
TLRKVGVEAAISLARELLEGGVPGIHVYSMNSTASTVEIREAIKEFYPSGRDSAS
>J3AJ37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus ratti FA-1 = DSM 20564|TrEMBL
MSKLLDKLKTDILVADGAMGTLLYADGLESCHDYYNISHPERILAIHKAYIDAGADVIET
NTYGAKRHRLKSFGYDNDIKEINQRAVEIARQAAGENVFVLGTIGASRGLKQCELSLEEI
VEETVEQAQALLETKQLDGLLFETYYDREELEAVLKAIRPLTDLPLITNMALHEAGITED
GRPLVEALSNLVMLGADIVGLNCHLGPYHMIQSLKQVPLFAQSYLSAYPNASLLSFVSDD
EKGQYRFSQNADYFEYCARLFVEEGVRLIGGCCGTTPDHIRAIKRGIKKLKPVERKVITP
LITEQEFIDEISKKETLADKAKKEVTIIAEIDPPKTLAIDKFVEGIKALDKKNIAAITLA
DNSLAKTRICNLSLASLLKDEVTTPFLLHLSCRDHNMIGLQSRLLGMDVLGFDQILAITG
DPSKIGDFPGATSVYDATSFKLLSLIKQLNQGKGYSGASLKRATHFTAAAAFNPNVRQLE
KSSRLIERKIKAGADYFITQPIFNEETIHQLGELTKAYDQPFFVGIMPITSYNNAVFLHN
EVPGIHLSETLLEKLKAVKDDKAACQAAALAESKALIDCALNYFKGIYLITPFLRYDLTL
DLIDYIQERTAVMKKRA
>A0A831XP10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MNREQFRARLEQGVLIADGAIGTMLALRGVPTPYELTNLLYPDTVRALHREYYEAGARLI
ETNTYTANRVRLFNLPERGSEAPPTYSLLEQFGSPEELVRRINQEAVRLAREAVGADALV
FGSVGPVGKPLEPIGETRLDEAEGAFREQMQALLEAGVDGLILETFIDPRELELAIRVAR
ELAPDLPLIASKGFVEDGETLMEGLPERFAHTVSALGVDAVGANCVVGPQRMLDIVRMMA
TGTELPLSSMPTPGLPQLVRGQVVYDIHPDYFGRYAVRLVEAGAQIVGGCCGTTPDHIRA
VAQAVSRTPVKRRAGGIRAVVRERKEEELPLAEPSRLSQILGKERVIAVELDLPRGLKVQ
KVIEGARLLKEHGVHVIDISDGARARLRMNVIAISHLVQREAGIEVMMHFACRDRNLLAI
QADLLGAHALGIRNVLAITGDPAQIGDYPTATSVFDVDAIGLVRILRRFNEGRDLAGNTI
GVRANFTIAVAYNPLAPDPETERDRLRKKIEEGAHLVYTQPIFEMRVVEETAELMNRLGV
PWLVGVLPLRSARHAEFMHNEVPGVSIPEPILRRMAEAPEEDALAVGLEIARRFVAEAAP
YAQGVYLMPPAGSAQIALQVIEALK
>A0A7C2IHR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MTRQEFHARLKQGVLVADGAVGTMLAMRGIAPPHDLANLTHPDQVRALHREYYEAGARLI
ETNTYTSNRIRLLNIPERGSELPAAQHLLEQYGSPEALVRQVNQAGVQLAREAVGTDALV
FGSMGPVGKPLEPLGEIRLQEAQQAFTEQAQALIEAGVDGIILETFADPRELMVAIRAIR
ALAPDLPLIASKGFIEDGETLMEGLPERFARELSTLEVDLIGANCIVGPQRMLDIIRMMA
HATDKPLSAMPTPGLPQLVRGQVVYDIQPEYFGRYAARLVEAGAQLVGGCCGTTPEHIRA
VAQAVAGVQPRRTTIAPQATLRERKPAELPLAEPSRLSRLLGKERVITVELDLPRGLSVQ
KVIDNARLLKEHGVHLIDISDGARARLRMNVMAISHLIQEQAGIEVMMHFACRDRNLLAI
QSDLLGAHALGIRNVLAITGDPAQIGDYPTATSVFDVDAIGLVRILKRFNEGIDLAGNSI
GMRANFTIAVAYNPLAPDPEMERERLQRKVEEGAHLVYTQPIFEMPIVEATATLCQRLRV
PWFVGVLPLRSARHAEFMHNEVPGIRIPQAVLQRMAEAPEECALEVGLEIAQQFIREAAP
YAQGIYLMPPAGNAQIALRVLQALE
>A0A7C4XKU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-3 bacterium|TrEMBL
MLRDKFRKGKVITLEVLPSVSVELDSLIKELKLFEGYVDALNIPSNPLGKLKPDSLSLAH
ILQEGTKIETIPHFVARHLTLLSFESQLLGAKALGIENILCVTGDSPVEGRSMFELNSSR
LLEVARNLRSGLTSARKAITPIDFCLCTSFNPNVPNLQGELIKAGEKCRCGAEVFFTQPV
FQPEGFVEIIRKLKLQKDIKIIAGLSFLYTKKRAFSLMKFLGIPYEYILKLEEINEIEML
SDTANRIRDYVDGFYIISIGKYENAMELVKRIKK
>A0A0P1KWM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea quebecensis|TrEMBL
MSTIKQRYESTDGPFISLEFFPPKTKLGKQNLTARMTRMTALNPLFITITWGAGGTTARK
TLELAAIAQRELNVPVCMHLTCTNTDKEIIDDALKLAHEADIRNILALRGDPPVGEEWQT
PSEPSEFQHAVDLVRYIKEKYNDDFCVGVAAYPEGHCEGEADGVAQDPRRDLVFLKEKVD
AGADFVITQLFYDVEKFLSFEQMFRNEVSADVPLFPGLMPINSYLLFNRAAKLSHASIPQ
AIRDRLPQECHSDDNKVRALGVDILVEIVEEIYKRTEGRIKGIHFYTLNLEKAIAQIVTK
SPSLSKILEEDKEDGLVEGVGEIALVDDDTAEEDENFKKRRRQSSHNDDLTCNRVLIDEA
SKSITSGREPSGAPSRKVVISISQGSGVLGKDATWDEFTNGRFGDSRSPAFGEIDGYGPS
LKVSNKKAYKIWGQPSSTDDIKTLFIRYLEGSLEALPWSDLGLSAETALIQEELIQLNER
GCLSLASQPATNSTPSTDKIFGWGPPGGYVYQKSFVEMFVHKQQWELEIKPRLEPLGSKV
SYYVGDSAETFYTNLDSSCSSVVTWGVFPNSEVLQTTIVEEESFKAWRDEAFSIWLEWSK
LFPKNSRSNTLLKQMHRDYYLVSIVHHDFSNCDALWDLLLA
>A0A2G8RTN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ganoderma sinense ZZ0214-1|TrEMBL
MKISRKIDQAAKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
ELTSELVKTCQKLIGIETCMHLTCTGMPKEKVDTALREAKQHGCRNVLALRGDPPVGKEW
EAVEGGFSYGVDLVRHIRTEYGDYFDVAVAGYPQTQNLPPEEAAREMEYLKGKVDAGATF
IFTQMFYDIEMFIAWVKAARAAGITVPIVPGIMPIQTWNGFQKATSLAKITVPQFFLDEL
EPHKNNDEKVREIGIRLVATLCRQILSADIGIKGLHFYTMNLEKGCRMLLEELNLVPRVD
VVKPLPWRQSLTPNRRTENIRPIFWANRTRSYLSRTENWDEYPNGRFGDSRSPAYGELDG
YGIWIKQSKEDGLKLWDTPTTIEEIRGLFSKFCFGKLAALPWSDTAPSSETTVIAQQLAK
LNELGFLTINSQPAVDGARSDDRVHGWGPSNGYVYQKAYLEFFVSPELLELLIPHIERDI
NITYYVINHRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGRQW
ATFYEPESPSRKLIDDIMNTYSLVNVVHNDFKKADAIFQPFYKAGAEYAAKHAALNGAAN
>A0A435FVX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.040.01.1.1|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>K9VKI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillatoria nigro-viridis PCC 7112|TrEMBL
MNRFRTACTTPGEFIITAEVAPPKGGDITHTIQMAQRLKNRVHAINITDGSRAVLRMCPL
AVSAILVQHGIEPICQVACRDRNQIGLQADLMGAHALGIRNVLALTGDPVKAGDHPKAKS
VFDLESVRLLQVIQKMNGGQDWNDKPLTDGVTDLFVGAAVDPQCPSWSGLQSRFEKKVEA
GAQFFQSQLITDFEVLDKFMHHVAAGCNKPILAGIFLFKSAKNAEFIKKYVPGVHIPQET
IDRLAKAPEPLQEGIKIAAEQVKLARQICQGVHMMAVKREDLIPQILDLAGIEPLS
>A0A2S9Z1A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. 13CS0277|TrEMBL
MATAHPTPEHSHDPAANPAPAAPVENFQLSITDTLRRTPAGRVPFSVEFMPPRDDAAEQR
LTRAASTFHDLGASFVSVTYGAGGSTRARTQRVAEQLAKRPLTTLVHLTLVEHTTADLKE
ILRGYARAGLSNLLALRGDPPGDPLGDWTPVPGGLRYASELIDMVRSMEECAHFDIGIAS
FPEGHYRAASLDEDTKYTVAKLRAGANYSITQMFFDVDYYLRLRDRIAAADPEQGEKPII
PGLMPITSLRSVRRQVELSGAYLPPALEDALVRAAAGDEEAHRDDIRKIGIEYSTHMAER
LISEGVPDLHFMTLNFARATQEVLHNLGMAPAWDASQGHDVLR
>A0A2E6ZDG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTASPAKTLEDTWALSRELFDLGLRPVPHLAARMVTSKKHLQTLLAQLQEFGASELFLVG
GDAPEPFGPFTDSLQVLETILELEHGLEHIGVTAYPDGHAFISAGTLSESLRRKQELLVA
GKVSGHAATQMCFDPEAIRVWLTDERNTGLTLPVHLGIPGVVERTKLLTVGARLGVGASL
RFLKKNRSTLARMFAPGGYDPNKLLIPLASDLKPLKVEGLHIFTFNQVENTVEWRQKAVE
GLRTERHP
>A0A532VG47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium Ae_b3b|TrEMBL
MKLKDLFEKGKFVVTSEIGPPKGTNIEPMLEEADLLKDKADAINVTENQSSVMRLGSMAV
CRLLKERGFEPVFQITCRDRNRLALQSDLISASVLGIENVLCLTGDHVVLGDHPQTKSVF
DLDSIHLLKVARGLGNGYDMVGNKLDGVPDLCLGAVANPGADPLEPQIIKMEAKVEVGAE
FFQTQAVYEVKKFEDFMKAAGHIKVPIMVGIVLLKSAGMARFMNANVAGVFVPDKFIKIM
AEASKEDRPRKSIEIAASLIKEMKGMCQGVHIMSLGWDRYVPSVLEAAELI
>A0A2S5D822|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoides mccartyi|TrEMBL
MKTVEFFKKKQVLSFEVFPPKRTSPIETIYSTLDELKGLHPDYISVTYGAGGSLNNNKTL
EIAANIKNRYEFESVAHLPCINLTKEDVLLALNTIRENGIENILALRGDINPDITPCTDF
SHASDLVAFIREHGDFNIIGACYPEGHPESKSIVDDIYNLKRKVDAGVSQLTTQLFLDNE
YFYTFRERVALAGINVPIEAGIMPVVNKKQIERMVSLCGVHLPTKFIKMMARYENNPIAM
RDAGIAYAVDQIVDLAAQGVDGIHLYTMNNPYIAQKIYEAVYRLLAA
>A0A254TC03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noviherbaspirillum denitrificans|TrEMBL
MKQKNFSIEFFPPKTPEGEEKLRATRAKLAELNPKYFSVTFGAGGSTQKGTLETVLDIKR
EGHEAAPHLSCVGGTRESIRAILQEYKSNGIRRVVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPEMHPQAKSPQDDLQNFVRKVKAGANAAITQYFYNADAYFRFAD
EVRKAGVDVPIVAGIMPITNYSQLMRFSEMCGAEIPRWIRLKLASFGDDTESIKAFGLDV
VTGLCERLLAGGVPGMHFYSLNQAAATTALWKRLNLSA
>A0A0C9Y2S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Laccaria amethystina LaAM-08-1|TrEMBL
MEQGLVDEVLKAVRERGIQNILALRGDPPRGEEEWIPSDPRFTHAVDLVSYISASPEYSS
DFCIGVAAYPDGHTESTTDEDKEIDYLKAKVDAGANFIITQLFYDVDRFLRWLEKIRSKG
ITIPVIPGIMPIQTYSSFARLTKLCGTRVPACIAEDLAPISHDDQLVKDYGIKLAVQMIR
RLRSEGGIQGFHFCTLNLEKSVQRVLETLRWAGVTPPVHNKLIQDTPGAMKSPAEMGPPD
LLITPTSATNTATSTLATISVTDGEAGRGELNNAATWDDFPNGRFGDFKSPAFGNQDLWG
GSGLSRSDVLAQWNDPKCLDDLTQIFLGHLHAKILTTPFSPTPLSSESLMILPHLERLTR
RGWWTVGSQPAVDGVSSGDKVVGWGPRGGYVFQKGFVEFFCEEKDVNVIESRVERNGLDW
VHYFAGNYRGECRSNVPEDGRNAVTWGVFPGQEIAQTTIIEKESFLTWKDEAFSIWSEWA
SFYRPGSEERKLLEGVRNERWLVSIVHHDYKDPQALWTFLFDGNDS
>A0A5C9BRQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellaceae bacterium|TrEMBL
MDKDGTNQPLFSFEFFPPQTQEGVEKLTATRKRLALLKPAFFSVTFGAGGSTQDRTFDIV
RQIQSDGHHAAPHLSCVGSTRERIRAILDNYKEMGVERIVALRGDLPSGMASIGEFQYAN
ELVSFIRAETGDRFHIEVAAYPEFHPQAKSPRDDMLNFRRKMSAGADSAITQYFYNADSY
FRFVEEIRKLGVTAPIVPGIMPILRFSQLARFSDACGAEIPRWMRKTMEGFGDDVESVQA
FGIDVVTRLCEKLLAGGAPGLHFYTLNQAEPSVEIWQRLGLPR
>A0A5J5I329|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium limneticum|TrEMBL
MTLNDPTHNAPIGPLYADLAGDARVSFEFFPPKTEKMEAQLWSAIETLAPLAPKFVSVTY
GAGGSTRERTHNTVARIAKETSLAAAAHLTCVAASKDEIGEIADAYWDAGVRHIVALRGD
PPEVGGRFEPHPDGYTGAADLVEGLMKRHPFEISVSAYPEVHPDAASAQSDLDNLKRKLD
AGATRAITQFFFSPDAYFRFMDKVGAAGITADIVPGIMPVSNFAATKRMAAMCNTDVPLW
MARLFEGLDEHPASRQLVSATIAAELCRKLYEGGVRDFHFYTLNRAELSFAICHLLGLRA
KVAVNA
>A0A2E0F452|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
KEISLIKQKIDAGAEYAVTQMFFDNQKYFDFVKKCREKGIKIPIIPGVKILDKPRQIDNL
EKIFNISLPDDLKNEARENIEHVEEIGTNWAIRQSEELINAGVPVIHYYLMNDTSCMLNI
LNYLHK
>A0A2W4XFB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIEKANGKSLFSFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYEYKE
LPSGLLEKKIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VVALRGDAVKNETYFKPEKEGNHYASELVTQITNLNKGIYLDDELQNSSSTNFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGASYIITQMFFDNKKFFDFVAKCRKEGITVPIIPGLK
PISTKKQLNLVPHRFKVDIPDELIMAIVRAKDADAVKQIGIEWCISQSKELIKEGIPVLH
YYSMGKSENIKAIAREVF
>A0A7W5M022|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK377|TrEMBL
MPQKKNDAPRRDIIFSFEFFPPKSQEMEGQLWDTVRDLQDWNPEFVSVTYGAGGTTKAPT
LSTVTRFLADTPFATASHLTCVSATKEETHQVVDSFRNAGVTHFVALRGDAPGGVGAPYQ
PHPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDQAADIDMLKRKADNGADRALTQ
FFFDNDNFERYLEKVRAAGVRIPVVPGIMPIQNLTQLKRFAGACGTVIPSFLDERFAGYE
DKPEERAKIAADVAAEQIEDLVRRGLHEFHLYTMNRAPLVSAVLDNLGFSRQTARSAGAA
A
>A0A3B0WA90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
NSIQQYGTEFISKLCEQLLQGGAPSLHFYTLNRSKATLDIVNNLTT
>A0A6I4VHP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. Aalb|TrEMBL
MTFFNANQCEVLNQRLAEINGRINISFEFFPPSTNEMEEMLWNSIDRLSSLRPKFVSVTY
GANSGNREKTYNIIQNIKARTGLKAAPHLTCIDTTHDELCTIARHYWMNDIHHIIAIRGD
LLPSKQKPKMYGYDLVALLKKIGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVETYLRFRDRCVVAGIDVEIIPGILPVFNFKQLERFATITNVRIPKWIKTMFQ
GLDEDLETRKMIGINIVMDMIKILSREGLKDFHFYTLNRADMSYAICHMLGLRPYN
>A0A3B0W2L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MNFKESLFNPAEFTLTFELVPNRAGHGHGQNRILQLARQAAADGRLRAVSITENAGGHPA
LSPEVLGIEIQAMGLPVISHFSCKDKNRNQMESLLFGWDRAGLQNLLVISGDYPQHGYCG
KPKPVFDLDSVQALDLISQMNNGQTECLTNNKDMTFQPTTFLKGVAVSPFKSLPQELLFQ
YMKLHRKAAAGADYIITQLGFDARKFEEVLLYTRLTGLDLPILGNVFIPNMKVAGLMYRG
EVPGCVITEGLYNDMCSEANSADKGKGARLLRGAKLLAILQGLGYAGAHIGGPGLTFADL
DLLMSEAAKMAADWRSLLPDLSYWPADGCYFFEFDPQTGLNLNDEAGLDKLPLPPLPLSY
RLSHFVHQAFFEPDGALYRPTSKICLSMESGGREKMLANIEHIIKLIIFDCQNCGDCRLS
DLAYLCPQSGCAKYMLNGPCGGSRDGWCEVYPGRKRCFWVLVYERLTAHGLSFANNIIAP
PRDWGLNKTSSWLNFFRNQG
>A0A3B0TMG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKNITDIFNLKEKTLSFELFPPKTDKGYQNLLKTIEGLCELNPDFISCTYGAGGGSRDKT
FDIVELIQNQHNILSVAHLTCVLHTKEEIKNILTNIKSRNIKNILALRGDPPTDNPDWQP
TENNFKYSSELCAFTREHFGNDFGIGVAGFPEGHVLCPDKNLDANYLKMKVDSGADFVIT
QLFFTNQDYFDYCARTKEEGVTVRIIPGILPITNYPAL
>A0A8H6AV23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrytis fragariae|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHHIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAAL
EEVKNDDAAVRNIGKDLVAEMCRRILEAGVHHLHFYTMNLAQATRMVLDELRLTPSNQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLENSIESLPWSEAPISSEADTIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHEP
DLTYYAVKKTGDVQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLNESFETSENGD
VDGVRFIEPQTVPLTNGEANGH
>A0A3B1CEP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MPEKFRDALGNRLLVCDGAIGTMFYSKGVTINRCYEELNIAQPDLVRELHRDYIKAGADI
IETNTFGANRYKLRNFGLEDKVAAINKAGISLAVDEARGGVFVAGSIGPLGISVEPYGKL
TATLAKSAFAEQGEELIKGGADLILFETFNDLNELETAITAIKSIDKDIPIIAQVAFEAD
GKTKYGATPAQAVSTIEPLGVDAVGANCSVGPADMLDVVNAMTSVTRLPVIAQPNAGMPK
LVDDRLIYLTTPDYLMTYGKRFIRAGARIIGGCCGTTPGHISVLKGAVKALSPSRVEVSQ
IEEAKREEIAETLREDKTPMAKKLVEGKWVQSVELLPPKGPDPSKTLVNAQKLKDGGIDC
INIPDGPRAMARMSPMSLALLFNNEIGIEPILHYTCRDRNLLGMQSDILGAEAVGIRNIL
AITGDPPKLGSYPNATAVYDVDAIGLVKMIKNLNRGLDIVGNQINGKTSIHIGVGVNPAA
ANMDEELRRFKLKVEAGAEYCMTQPVFETDKLFRFLDSIDKFRIPALVGILPLASSRSAE
FLHNEVPGMQIPDDIRNRLKNAGDDAGEVGIEIAREALSMTRDRVEGVYTMVPVGGAQTA
IRVLAP
>A0A3A2J0D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcales bacterium|TrEMBL
MHTPKKHAQLYSFEFYPPKSPEGAVTLQQVYSKLAELNPDFFSVTFGAGGSTRDKTFDTV
IDIQSKGLAAAPHLSCVASTKANIRAILKDYQDNGISKIVALRGDLPSGMMSAGEFRYAN
ELVEFIRQESSDHFQIHVAAYPEVHPQSESATSDFKNFKRKVDAGANAAITQYFYNAEAY
FCFVDNCEKNGITIPIVPGIMPITQYTQLFRFSEMCGADIPRWMRKRLESFGDDKASVQA
FGLDVVSELCQRLLDNGAPGLHFYTMNQSAPCLAILDRLKP
>A0A3B0T7L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MPSPVAVIACGALAREILAIVKMNGLIHVTLKCLPASLHNHPDRIPDAVARAIDELAATH
RKIVVAYGDCGTGGLLDRMLEARGIARIAGPHCYSFFSGNDAFAGRATADMRYFYLTDFL
VRQFETLVVCPLGLDRHPDLLPAYFGAYEKLIYLAQIQDKKLDVKAQEAAAFLGLGYEKR
NVGYGDLAPFLTALEGAPVPSPRPLPPRSEFRSEIAPPVPLARLYNSGAERTLTVAKPHA
DKTMPPVAEYTAPPLIASMEATPNQAATTSALEGLLPRGTAVYLTDLGTDNASTTIAAAV
RLRHLGYEPVPHIAARRLPGPAALADFLARITGEAGVGDVLVVGGGAARPFGPYAASIDV
LETGILDKYGITRIGIAGHPEGSPDISARTVDEALRAKAAFAERTGANMRIVTQFGFDPA
AAIHWLEGLTAAGFELPVHLGVAGPAKISTLLKYAAMCGVGPSLGFLRQGAGLLTAIATN
YSPDAYVEPVERWHRSSPASGLAGIHVFPFGGLKNSAKWLVDRGSLKFPNGESGGAPLGF
QEGGFL
>A0A0M3AEE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. AG1|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1E2S3Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloligella halotolerans|TrEMBL
MLHRDHHRSRALCAGDINVSFEFFPPKTDKMEQTLWSSIGTLAPLHPNFVSVTYGAGGST
RERTHSTIDRVLKETALKPAAHLTCVGTTKEDIDEVIRDYWEIGVRHIVALRGDAPGGVG
APYEPTPGGYVNAADLVAGIKKIAPFEVHVAAYPEKHPQSPTVEADIDNLQAKIDAGADA
AITQFFFDNDVFYRYIEKVRARGITVPITPGIIPIHNFKQVASFATRSGTYVPDWLGQRF
EGLENHPVTQNLVAAAVAAEQVLELVDQGITDFHFYTLNRAELVYAICHLLGLRPAVTSN
LEAAEAVS
>A0A0A1ZPA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus str. MIT 9116|TrEMBL
MKSKLQQILEKKSKVITAELMPPRGASPIRSLKIAQLLKDKVHAVNITDGSRAIMRMCSL
AMSKLLLENGIEPIMQISCRDRNKIALQSDILGANALGIKNILCITGDSVKAGDQQDAKA
VHEFESVRLLEQIQSFNQGIDPTCGELSDKKTFIFSGAAADPSCKNQRSLQNRMRKKKEA
GARFIQTQMVMEKENLIEFCEKISNPLEIPVIAGVFLLKSYKNALFINKYVPGAYIPENI
LNRLKDAKHPLQEGIQIAAEQAQDFINIADGIHLMAVKAEHLIPEILEKADLNLEY
>A0A3B1BW44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MQIKDRIAKEKGFVSLEFFPPKEKEAWPSFFSEVEKLKRINPLFVSVTYGAGGGTQAGTL
DIVTRLKKEHGLEPMAHLTCVGASEKSLHGFLSSLEKAGILNILALGGDKPQNAGDSFVE
NEKFKYASDLVGFMRKHYADFGVGVAAYPEKHPTAVSAEDDLGRLKNKLDIGGDFAVTQL
FFDNELYFDFVKRAKKIGIEKPVIPGVMPILSLKRIKRIISMCGASIPAGLMAKLNEADK
KGGDSAVEKVGIEHAIAQARDLLDNGAPGVHLYTLNKADLCLSLYDGLMS
>A0A3R9IUH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1X1JUN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDIPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A395YF92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM58-1XD|TrEMBL
MKIKEILEQRKPTISFEVFPPKTEDKYETVKEAALEIAKLKPAFMSVTYGAGGGTSRYTV
DIASTLMEQGGVTPIAHLTCVSSTREKVREVLGELKIREIENILALRGDIPEGGPVENDY
RYASELIYDIKQAGDFCIGAACYPEGHVESENKTVDIGYLKEKVEAGCDFVTTQMFFDNN
ILYNYLYRIRERGITVPVVAGIMPVTNVSQIKRICQMSGTALPVRFKALLDRFGNSPAAM
KQAGIAYATEQIIDLIANGVNGIHVYSMNKPDVAAKIRENLSDIID
>A0A6M3ZX45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum rubrisubalbicans Os34|TrEMBL
MSTPNFSIEFFPPKTAEGAEKLRATRAKLAALQPKYFSVTFGAGGSTQQGTRDTVLEIVG
EGHEAAPHLSCIGSSRASLRAILEDYRANGIKRLVALRGDLPSGYGAMDQASSEFRYANE
LVEFVRAETGDWFHIEVAAYPEMHPQARSPQDDVQNFARKVKAGANSAITQYFYNADAYF
RFVDEAAKLGANVPVIAGIMPITNYSQLVRFSDMCGTEIPRWIRLKLASYADDTESIRAF
GLEVVTQLCERLLAGGAPGLHFYSLNQAGPTQAIWQQLVK
>A0A2D1SY46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solibacillus sp. R5-41|TrEMBL
MGLLEDLKTKVLTADGAIGTLLYSYGLDYCHEEMNILRPEIIEKIHGEYVAAGADIIQTN
TYGANAIKLARYGYEYRVQEFNEAALQIAKRAATPGGQYVLATIGGIRGVRKNDVTLAEI
LDAFEEQAKVLLAGQPDGFLLETYYDFEELSHCVHLLRTLTDLPIIAQVTMQDPGVLQNG
LSLNAALTELAALGADIVGSNCRLGPFHTIQSFEGVELPENSFLSASPNASLLDVEDGRV
VYESEADYFARAAVELVEQGVRLIGGCCGTTPKHIAAVKSRLAHIKPITEKKVKQGRTEF
VRVPEPRKQEPLHLKAKRERSVIVELDTPRHLEIDGFVEGAKELYNAGADVIMMADNSLA
SPRISNIAMASILKQHGIRTLPHLTCRDRNLIGLQSHLMGLDALELHDLLVVTGDPTKVG
DFPGATSVYDVSSMELISLIKQLNEGSSFTGKTLRKQANFSVAGAFNPNVRVLDRAVARL
EKKIEHGADYFISQPVYTKEKIKEIYEATKHLETPIYIGIMPLTSFRSAEFLHHEVPGIK
LSEEVLARMEACGEDKEAATKEGVKIAKELLETACQYFNGIYLITPFLRYDMTLELIDYV
KAFDVKYKGAQTNA
>A0A498H3N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus sp. WG1-DM|TrEMBL
MSLKTNVTYYPAMPSAFKEKLLSDEFIVTSEISPPKGVDVSSVFEEAGLVRDYVDAFNVT
DNQRAVMRMSPLAMGHLLKEQGLDIIMQFTCRDRNRLALQSDLLGAYAMGMENVCIMSGD
YPTKGDNPGAKPVYDLDSVQLLGAMNQLEDGYDIAGNPLESAPSFTKGAVCNTEPDQPLQ
LMKLEKKAHMGIDFFQTQAVYDIGHFETFMENISHMEVPVLAGLIPLKSAHMARFMNEKI
PGIRVDDELIARMESSTDPAEEGLLICAEQIRELKKVCRGIHLMPIGHYGHITALFEMAG
LHEKH
>A0A7S0MVH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptomonas curvata|TrEMBL
PEHVAAIASAARMFGGGASIGPAPIAAPGDAGATRAGGGKGGKGTAAAAMPAIPVKDRSL
LASKIWRIWEERLGCGTRKQAPQGPEDFVVSVEVNPAPGLSTAKPVATARMLRKGGVDVI
NIADGPRATVRMSNSALAEAIQREVGSETILHMCCRDRNLLGLLSDLLGNHSRGLHNMVV
ITGDPPKMGDYPKATAVFDVDSVGLLRIIKGLNTGLDPAGKSFDAQARFFCATGAEPGAV
DYEREMRRLRDKIDAGADLVMTQPVYDSDVMRRFLADVAALPRPVPVLLGLCPLVSSRNA
DFLHNEVPGMSVPQGIRDRMARAGGGPAGQAEGVAIAQEMLEEFKDQVVGCYVMPQLGKY
DLALDVLAGLGYGKDD
>A0A7C1AME1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulforhabdus norvegica|TrEMBL
TQCIYNMDKFREYMKRVVDMGLAEKCYILAGITPLKSLGMARYMARFVPGLDVPDYYLKR
LAGVEKKKQAEEGIKIAVEQIQEIREIEGVAGIHLMAIEWEHKVPEIIKAAGLYPRPEVE
>A0A2P7PZI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptostreptococcus russellii|TrEMBL
MDNVDRIKSKLPLLFDGAMGTYYRDSIKSPLPECEMANIFDRESILNIHKEYLEAGAIAI
KTNSFGANKRALNCSENVLATIIESSYNLANEAVADYCADNKINIDDRFVFADIGPIAHP
SEPYNYKEFLEEYVDIVDKFLELGAKNFIFETLDEDIFLLDLCEYIKNKEEDSFIIVSFA
INPDGYTRKGYYGEKLIENVSKSNFIDSVGFNCISGPGYLLNTIEKINLDGKIISIMPNA
SYPTIINNRVYYSDNSNYFANTMMDFLDYGVEIIGACCGTTPKHIGKMNRLLADKKVSKN
IKRQISNDNRKASHKINTKEKPNIFYDKLLSSKKVIAVELDPPADINIEKYMENAHSLKK
AGVDAITIADCPVARARIDSSLMAYKLKNELDIEPIVHLTCRDRNLNASKALLLGLNIEN
IRNLIIVTGDPIPNAEKNEIKPVFNFNSRILAQYIKDLNEKLFTNSMMISSGLNVNARNF
AIELEKAKNKELAGVEVFFTQVIASERAIKNLIWAKKELKSKIMGGIIPIISYRNAIFMN
EEISGISIENEIIEKYKGKSKEKSDKLAVEISLEFMKRIEDKVDGFYLITPFSRVDIIEE
ILKKYMNK
>A0A6G3A752|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID2999|TrEMBL
MALGTASTRTDRARTVRDILATGKTAYSFEFYAPKTPQGERNLWNALRRVEAVAPDFVSV
TYGAGGTTRATTVKETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWIAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEILPVTSVKMLERLPKLSNALF
PAELKERILSAKDDPAAVRSLGIDFTTEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A541BN66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus spelaei|TrEMBL
MTHTPSIVDRIGASNGRIPFSVEFSPPRDADAEARLWRAVRAFERLGPAFVSMTYGAGGS
TRDRTVRVTGQLAEDTTLLPVAHLTAVGHSIDELRAMCGAYADRGISNILVLRGDPPGDP
LGEWVKHPDGVEYAEDLVRLVRDMGDFHVGVASFPEGHYRAPDLEHDTKYLVSKLRAGAE
YSITQMFFDVEDYLRLRDRVAKFDAEQGAKPIIPEIMPITSLRSARRSLELSGSKLPPVL
EERLTRAAGDGPEENRAAVREIGIEVATEMSERLIAEGAPCLHFITLNFARATSEVLTNL
GMAATVH
>X8KDB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. SR1|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1S1X8Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium amazonense|TrEMBL
MTQTPRTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGQAAAPHLSCVGSTRENIAAILNEYRGNGIRHLVALRGDIPSGMVGAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSADDDLDNFVRKVRAGADSAITQYFFNADSYFRF
VDEIRARGLDIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRLRMQAYYDDTASIRALGL
DVVTELCDRLLQGGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A3C0F3B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomarina gelatinilytica|TrEMBL
MKVTEHIKNANGNTLFSFEILPPLKGQNVQSIFDNIDPLMEFKPPFIDVTYHREEYVYKE
LENGLLQKKVVKKRPGTVGICAAIQNKYRVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKTETYFKAEKEGHHYASELVTQISDLNKGTYLDEDLLNSSCTNFCVGVAAY
PEKHMEAPSLDSDIHFLKKKIKNGAQYIVTQMFFDNNRYFEFVEKCRREGITVPIIPGLK
PIATKKQLNLIPHRFHVDLPEDLILEVVNCQNNEQVRQLGIEWCVQQSKELQKAGIPVLH
YYSMGKSDNIKAIASQVF
>A0A2A2S354|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. MD40|TrEMBL
MKITEHIQNANGKTLFSFELIPPLKGHSIQGIYDAIDPLMEFKPPFIDVTSLREDFIYKE
QENGLLQKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLHFLGIEN
VLVLRGDARKGDSSFVPTPNGHCYATDLLQQVVNMNNGVYLHEHYDNMMRTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGAKFIVTQMFFDNQRYFDFVNGCRAAGINVPIIPGLK
PITSSKQLISLAKTFHIDIPEDLSDAIHEAKSEKDVKDIGIEWMINQCKELVKFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A140NPI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia stuartii (strain MRSN 2154)|TrEMBL
MYAADLVELLKAEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRAITQFFFDVE
SYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPSWMSRMYEGLDNDPESR
NLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A1W2B7Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocicer vacuolatum DSM 3385|TrEMBL
MSDLKSGSNLEKVLTAGHFAFTGECGPPKGANVEHLVEKFQHLKGNVDAVNITDNQTAVV
RMSSLAASHLMVHEGMEPNFQMVCRDRNRLAITADILGAQALGIKNMLCLSGDHQTFGNH
PQAKNVHDIDSMQLIKLVTTMRDEGTFANGEEIDVPPRLFVGAACNPFADPFDYRVYRLA
AKINAGADFIQTQCIYNMDKFREFMRRAVDMGLHEKCYILAGVTPMKNVGMANFMKKFVP
GMDVPDSVIKRLKGVEKKDQAEEGIKFAIEQVEEFKEMEGIAGVHMMAIEWEHMVPEIAE
RCRVLPRPSV
>A0A0N4UK23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dracunculus medinensis|TrEMBL
LEPIRHNDDAVRKFGIHQAVHLCRELLNKGLTTSIHLYTLNRESASREILQELGLWIKKP
MRTLPWKSFGCNHPVRYKETVRPIFWSTRPNSYVFRTQDWDDFPNGRWGNSSSPAFNDLA
DYYLFYLKGHLSKEDQLKMYGELKSIVDVQNIFVSFISQQPNQNGIKVTRLPWNEQEIGT
QPETSLIKEQLIWCNKHGILTINSQPAVNGASSTDPLVGWGKPGGYCYQKAYLEFFTSQK
NTESLRQLLPLYPRLSCQIINHNATIDWTNGESTMPIAVTWGVFPGSEIAQPTVVDPLSF
RVWKDEAFETWNNW
>A0A8H0DYY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. 005/A4HT-01/001|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSLDEIKR
SFREQLYILLNEEPDGLLLETYYDIEEAKAVLEIARKETALPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPLLQNSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHISAMAEAVKDLAPITEKEVKILKEEIIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKSAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIREIMAKAGENKEKQRTEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKEPNIHANYH
>A0A7X0B1B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirillum iridis|TrEMBL
MTTMTEMTEGLEKGLGGGEPLVTVPRGLRISFEFFPPKTEKMEQTLWQAIRRLAPLSPSF
VSVTYGAGGTTRERTHATVTAIQQQTGIPAAAHLTCVAATREEIDTIARAYWEAGIRHIV
ALRGDPPQAADGSGGLGGSGYVPHPGGYAYATDLVAGLKRVADFEISVACFPETHPEAAS
PAADIDNLRRKVDAGATRAISQFFFDTDAFLRFRDKVAAAGIGIPIVPGILPITNFGRAV
DLGAKCNCAVPDWMNDLFGGLDAEPETRQLVAATVAVQQCLRLEREGVRDFHFYTLNRAD
LTVAICHMLGVRAPQPV
>A0A345XDE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. COPE52|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTNRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQVALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0Q5H3Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. Leaf139|TrEMBL
MENHNFSIEFFPPKTPEGAEKLRVTRRKLAELNPTYFSVTFGAGGSTQQGTLDTVLDIMA
DGHLAAPHLSCIGATRASIRTILQQFQSQGIRRLVALRGDLPSGYGGAGELRYANELVEF
IRAETGDWFHIEVAAYPEVHPQARSPQDDLLAFERKIKAGANAAITQYFYNADAYFQFVD
NAQKLGIEVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VSSLCERLLAGGAPGLHFYSMNQAAATTAIWQRLV
>A0A1Q3LDM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. 69-7|TrEMBL
MSVATATPAAAASRIAGCPKSMAYGPCGGVNADGTCEVHPTPCVFLTRDLPVRWTSPATE
ETPSDAVSEHPSRPATPAGRELVEIAARRPLVFTGFPVRALRADAVRPTAEALAGSVDAV
LSGDAGRSRVQFPPSYRAALIGATGLRVWMGFNARDRNRTALERELLSLRALGVAGVHCV
TGDHTQTGDRPDARPVFDLESTTTLPRAASLGLLPSFAESPAAPPVAERGARVAEKQRAG
GRMCLTQYAGDAEEVAAFVALCRAAGADVPVLAGVPLVVDREGAELLASFHAAKLPSGFI
DRLFAARDVRAEGIRLAVAYGRALLATGAVGGVVIAGGARPGGEAAYAADLATVARELGG
GS
>A0A4Z0A745|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hericium alpestre|TrEMBL
MKFAQKLQGSERPFYTLEFFPPRTDQGFTNLISRISRLAEVKPLAVSITWGAGGTTRERS
LELAAVTSKELGLETILHLTCTNMEKGMVNDALKAAKDLGVKTILALRGDPPRGKESWVP
TDPRFTHAIDLVSYIHSNPEYSDWFSVGVAAYPDGHSDRVLSEDEELNYLKAKVDAGADF
IITQLFYDVDNFLRWKDKVRRKGIDVPIIPGIMPIQTYSSFRRLTKLCGTHIPPSLEADL
EPIKHDDSKVKEYGITLAIKMIKRMVNEGGIRGFHFCTLNLENSVQRILESLDWIQASEI
TKVPNRLIADTPRAVVHADGADIKRTVTPATATSTAMNGLQAQVPRDGDVGKGEVNNAAT
WDEFPNGRFGDVNSPAYGTQDQWGGFSTLHSATSSQWPRPQTEADITAISLRFLSSETDS
YPFSPSPLSLESQRILPHLKRLARLGWWSVGSQPAVDGESSEDPVIGWGPAGGYVYQKPF
VEFFVSQEEVERIEKKIEEKGDGWVDYLAGNFAGEVKTNVQDGKRNAVTWGVFPGQEVIQ
STIIEQDSFLAWKEEAFSIWTEWASLHPPKSQERTLLEAIRDSRWLVNITYHDYKDADAL
WNFLFEGTPEVPLD
>A0A066VBR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tilletiaria anomala (strain ATCC 24038 / CBS 436.72 / UBC 951)|TrEMBL
MSDHDISAAHQPSPASSLSLAHPSHLTTKLAKERPLYSLEFFPPKTTQGLENLYARIARM
ARPAWVNVTWGAGGSTDRWSVEMATRIQKGQLPYSGSGSLSLESKLKAHQLNQGPDSPGS
PSSAEGDTTSPSSGIDALLHLTCTNVTVESLRTSLAQARNSGVRNILALRGDPPRGHEYW
VAADDRFQHAVDLVRFIRQEHGDFFCIGVAGYPEGHPDDALLANHTVGDGEHGIDLVERD
IQNLLAKQAAGAQFVITQLFYDVDAFLAWERRAHAAGVHIPIVPGMMPIVNFQSFRRMTM
LCKVGVPPRVLSALEQIKADDAQVRTYGIELCANMIARIWTEPHSRVKAFHLCTLNLEKS
VSRVLAQCSWWNHSTAAAAARQGEECDINSTNGISIGRNRKIQTDTIIRNDTWDEFPNGR
FGDIRSPAYGEMDGYGASLKVPPAEALRAWGHPTSIGDISDLFIKYLEGKLEVIPWCDGP
LMQETESIREALLRLNASPTTRNAAGESGKAWWTVGSQPSVDGIDSSDPAFGFGPRGGYV
YQKAFVEFFITEQEKEALKEQIAEHGSSVVSFFAGNRHGAFETNMEAGKSNAVTWAVFPG
REIVQPTIIEEDSFKAWCQEAFAIWAEWELLFPPQSATKQLLHEIGEQRWLITVVHHEYR
DPDALWRFLTTRNSNSTCTTNNK
>D5HB29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinibacter ruber (strain M8)|TrEMBL
MKVTEHFDRESEPLISYEIIPPKRGGSADQILGVVEELMPYEPPFIDVTSHSAEVEYKQK
DDGTWTRCVKRKRPGTIGLCAAIEARFDIDTVPHILCKGFTREETEDALIELNYLGVENV
LAIRGDDNGYEKSISGNRSRNEYAVDLVRQIQDMNEGTYLEDLMDAEPTDFCVGVGGYPE
THFEAPNLAWDIMRLKEQVDAGADYIVTQMFFDNEYFFNFVDKCREVGIEVPIVPGLKIL
KRKRHLRLLPKYFHTEIPEELAAEVDAADPDDVERIGVNWAIRQARELMEAGVPGIHFYI
MSSADTVKKVVEPMHEEVA
>A0A1Y0EE73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yoonia vestfoldensis|TrEMBL
MSSPSVSFEFFPPKSLEGSFRLWDCVNVLAPLDPTFVSVTYGAGGTTRQLTHEAVSTIHR
TSGLNVAAHLTCVDATRAETLEIAQNYAAAGVREIVALRGDAPKGQATFTAHDDGFASSV
ELIAALAETGQFTIRVGAYPEKHPEAADQAADIAFLKRKIDAGATSAITQFFFEADTFFR
FRDACVKAGITAPIIPGILPIENWTGTQKFAAQCGTHIPQVIRDAFTNATRDGTTDLLAT
ALATELCDDLVRGGVDDLHFYTLNRPELTRDVCHALGVTPKARLQNVA
>A0A254ULL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioclava sp. JM3|TrEMBL
MTTPKVSFEFFPPKTLDASFRLWETAQVLAPLKPEFTSVTYGAGGTTRKLTHEAVGTIHK
NYGLNVAAHLTCVEATKAETMDIVDAYAEVGVTEIVALRGDPPQGAKHFTPHPEGFASSV
ELIEALAEDGRFTIRAGAYPEPHPDAADNMADVRWLKRKVEAGATSAITQFFFEPETFFR
FRDACEREGIDAKIIPGILPIQSWKGAKKFAQSCGTSIPAWVEEAFEAAIRDGREHLLAT
ALCTELCDKLIEGGVEDLHFYTLNRPGLTRDVCHALGVTPDTVLEKVA
>A0A4Z1K4X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrytis elliptica|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRAIDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDGFEQKLRDHPSGAFKDIPIIPGMMPIQSYQMI
KRTTKLSHAKLPSTIITRLDAVRGDDEMVKKVGVDILSEMVEHLKGTKSQYSGPRGFHFY
TLNLEKAVSFILERTELIPDAETVAALEPEFVPTIPDIADLMSIHSGSHKRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGPKNGFVFQKAFVELFL
PTADWKTLHAKLTSPELRDTVSFYASNAKGDFISSDEAVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSQTRKIIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLN
>A0A1Y0EAH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yoonia vestfoldensis|TrEMBL
MSLLPFFKTKEPQASAVNPAIEALLRDYSIEVMPRTAEKVENFRDLLPQGTRVYIAHIEG
TPIADMVATARRLAMDGYKVMPHFPARIIKDRATLADWIARYQGEAGVDQALLLAGGVAQ
PHGDFESSMQLMESGLFGDFKRLHVAGHPEGNRDIDHDGSDTNVMAALRWKQKFSETSDA
QMALATQFAFEAGPIIAWADALRDAGITIPVHIGIAGPAKLQTLIKFAIACGVGPSLKVL
QKRAMDVTKLLLPYEPTEVVAQLAAHKAANPDFNITHVHFFPLGGIKTNAQWAIDNGGAS
ALPASQR
>A0A2S8JF23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus opacus|TrEMBL
MTFDSVRGRASEGWVTRTPSIVDRIRSTMDGRVPFSVEFSPPRDEAAEARLWRAVREFER
MGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWEKHPNGVEYAEDLVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSV
RRVLELSGSRLPAHLEKRLAAAAGDGPEENRAAVREIGIDVATEMSERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSGVADPAPVTPARVS
>A0A3E2WB46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster aldenensis|TrEMBL
MKTSEFFKQKTVLSLEVFPPKRTAPVDTVYKTLDGLKGITPDFISVTYGAGGIGNSRATL
EIASSIKHRYGIESVAHMPCLHLTKEEAARILEQLKAHQIENILALRGDRIPDMEPAGGF
KYAADLVGFIRDHGDFNIIGACYPEGHQESGDLVQDIRNLKQKVDAGVSQLITQLFFDNQ
YFYRFRERLDLAGIRVPVEAGIMPVVNKKQIERMVSLCGVKLPQKFISMMERYGDNPAAM
RDAGIAYAVDQIVDLAAHGVDGIHLYTMNNPYIANKIHESVFRLMAS
>A0A1B7LC99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotomaculum copahuensis|TrEMBL
MKTESKLESILNKGEFAVTAEIGPPKHSSPEAIKHHAEMMRDYVDATNITDCQTAIVRMS
SIAAGLHVMKNGIEPIIQMTCRDRNRIAMQSDLLGAYSLGVRNVLCLSGDHQKFGNHPTA
KNVYDIDSMQLINMVRRMRDDKVFLCGEEIKQAEPRFFIGAVANPFADPFEFRVVRLEKK
INAGAEFIQTQCIFDMERFERFMEMVRQRGLHERVHILAGVTPLKSWRAAKYMQTSVSGM
IVPDEIVERLKKAEDPKKEGIEICIEQIKHIRNIPGVHGVHIMAIAWEEIVPEIVQRAGL
YPRPKAE
>V6MDF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus panacihumi W25|TrEMBL
MTATKLDLREYLQQHLLVGDGAMATQLHRLGVPVGISFEELCLSNPKLVLEVHNSYYQAG
ARLLETNTFAANRDALARYGMEHRVTRINRQAVSLAREAAQGEGYVAGSIGSILAGRVRK
KVLDEYRDQYEEQAIALLHAGVDALLLETFLDLEELLLAIDVIRPLTNIPLITQLATLEV
GRTRDGYSLTEAFARLKTAGADVIGLNCRLGPAEILRSFEQVQAPEGAVLSAFPNAGRLG
LTDGEYAYKSTADYFAESALRLREQGVRLIGGCCGTTPEHVRAMADALAALEPKERVNPT
IVPGERPQVTVTSIRDQDRPSIVEKVKSNTTIIVEFDPPRDLDAESFLEGCCELHNAGAD
AITLADNSLATVRMSNMALGALMKSRYGIDPLLHLACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGISFSGRPLKQKAQFIVGAAFNPN
VRQIDAAIARLEKKVEAGADYIMTQPVYDAESIKLVYEATKHIGVPVFIGIMPLTSQRNA
EFLHNEVPGIKLSAEALERMKRVQGEEARQEGIKIAKELVDTAIHYFRGIYLITPFNYYA
MAAELIQYTRQQSELLKVPVQG
>A0A841PMQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomicrobium halophilum|TrEMBL
MNFLERIKNDILIADGAIGTLLYARDITGSIEHANLYAEDKVIAAHKEYIKAGADFIQSN
TYAANALKLERYGLEQEVTTINRRGMQMAKQAAVGENVHVAGTIGGIRDGRATQFSNDEV
KAATEKQAEALLSEDPDAILLETYYDLQELVQALRIIKRLSPEMPVVSNVSLGDVGILHG
GIPINHALVRLLNEGADVVGINCRMGPAQTIASLEEVALPEGAFLSAYPNASLPGIQDGR
LVYQSNPDYFKNKAEAFQEQGVQLLGGCCGTTPDHIRSFKEALKNKSPKRKTHAKVSNVQ
QQQEAEIGHTISLDKTDPSVIVELDPPKSLTKMDKFLKGSQALHDAGVDAVTLADNSLAT
SRVDNLASATMIKQQSGAHPLLHIACRDRNLIGMQSHLLGLHALGMRDILAITGDPTKVG
DFPGATSVYDLTSFDLIRLIKTMNEGFSHSGRPLGLQTQFTVGAAFNPNVSSMEKAVKRL
EKKIVAGADFVMTQPIYDVGTLERLREATNHLDIPIYVGIMPLINGRNAEFLHNEVPGIQ
LTDQVLAKMAACGNDVQKGEEEGIAIAKELQEASLDLFGRLYLITPFLRYHITVSLTNDA
LVYNTKKSFTS
>A0A7H0GXZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter qilianensis|TrEMBL
MKVTDHLIKADGKTLFSFEVLPPRKGENIQNLFSNIEPLMEFKPPFIDVTYHREEYVYRK
QPNGFLERKTVRKRPGTVGICAAIKNRFDVDTVPHLTCGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEPHFIPEPDGHAYASDLIEQVSCMNKGRYLDDEQEDTFPTDFCIGTAGY
PEKHFEAPNYGSDIRFLKQKMDRGAEYIVTQMFFDNEQFFNFEKRCRAAGITAPIIPGLK
PMTTKSQLTMLPRTFFLNIPEELAEAISQCRDNEDARRIGIEWCINQSRELMAHGVPCLH
YYSMGKSESIRRVAKELF
>A0A7L5BJY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium oryzihabitans|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNPEMETHLWETVEELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIGTAYK
PHPEGYENAAALVKGLREIGDFEVSVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFAGYD
DDLEGRARVAAEVAAEQIADLQRRGVSEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A811YP59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nyctereutes procyonoides|TrEMBL
MDQPTPGVLPARVRCSRLGLWTLEAGRVGFSVPPSISRSPAMVKEPRGDGGPTPHSEGSS
SGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDRWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYLS
GEPNQHGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLKGPSPEREAEAL
>A0A7C7RNH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteriaceae bacterium|TrEMBL
MEPRSHLQKVLSEGHFAVTAEIGPPKSADGEVVRKKARILKGYVDAANITDCQTAIVRMS
SIASAVLVMAEGVEPVIQMTCRDRNRIGIQADLLGAAALGVKNLLCITGDHQKFGNHPEA
KGVFDLDSIQLTAMVRQMRDEGKFLCGEELTGARPEFFIGAVENPFADPFEFRVKRLEKK
VKAGAEFIQTQIIYNVERFKKFMEMARDLGLTEKVYILAGITPPKSFGMARYMKYFVPGL
DVPDEILKRMKEAKDKREEGINIAIDIIQQVREIPGVAGVHIMAIEWEEAVPEIVKRAGL
HPRPLEAEVKPAIAVEVERPEKIEVVAPPKEEEEVAEGPPKIEIPVEAVKEVFSSVRSSI
ESLREGINLLHDSLVRLERALLGGEVVPPEVPQVEVKVEEKPVVEEKPAEEEKPAEKEKA
VEEIKKEVKPEEEKPEEKPAEEEPEAKPMAEEPKAAEPKPEEKPAAPAGPPPEGVELGGF
IGEYRPLSERAAGLPEDLYKDPGTAFIREVEIGKGEKAFKVGGTNVLPFQLFEGEMKNRP
RIAMEVLDVKPENWPDSLAKYFEDVFDDPAAWAKKCVETYEAEAVCVYLMGTDPNYLDLD
AKHAREVVEKVVKAVDVPIVVWGAGHAEKDVEVLREVAEILGDRGAVIGPVEEANHRTLG
ATAMGYGLPVVAASPIDVNLAKQLNILLENIGVSLDKILMDPSIGALGYGLEYTYSVMER
IRIAALYAQDEKLQVPFVCNVGREVWKTKEVGLPTDEMLGDQEVRGVLMEAITSVALALA
GGDLFIMRHPKAIELTKTILSALIQEN
>A0A1H9SFG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnobacterium bovis|TrEMBL
MFKEKNVYLFDGGFGTYYSQKYEESSNRCEVINLKNPQKVIDIHVEYINAGVDAIKTNTF
GAFFENFGNDYEKIIKTGYNLALKAREISRRNVDIFADLGPVTGDEVVNQIEEYKKVVDV
FLEEGATNFLFETLGDSSAVIEIAKYIRQRKKAATIVVSFGVMPDGYSPDGFFVKDLLEE
VLNDVNIDAIGLNCISSAIHLNNLLLRLVNTYKFDITQKAFLFMPNAGYPVVRGYRTFFE
GNIDFFEKQIEYALGLGVSIVGGCCGTTPKYIKKIKDGINNFKKNTDTDQNLDGKERKCL
DENVNHNAELNLNKINEIKSEIKELLFSDDNIKADSIETNNNKLKTISDNISKTGKIFAV
ELDSPKNDDTSTFMKNAKKLQEAGVDKITIADCPIARPRMDSSLLACKVKRELGLDVIPH
MTCRDRNINATKALLLGLSAEKIRNVLVITGDPIPSAQRDEVKSVYQFNSRKLARYINSL
NQELLNGKINIYGALNVNAVNFNVELDRALQKMEEGVCGFLTQPILTHRGFDNLKIATEK
LKGALILGGIIPVVSERNARFMQSEINGIDVDDEIIERYVGKTKEEARVIAVELSVEIAS
KIKDYVDGYYLMTPFNRTDIIIDVIKRIKEL
>Q05FX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carsonella ruddii (strain PV)|TrEMBL
MKNISFEIFPCNNIKDLSVLINYLNKNKPSFVSVTFGKINNLKFVKNIQKQISTKIIPHL
ICDNIFNIINYIIYFIKIKIFNFLIITGDKNKNNSIKYIYFIRFLFGHIIKIITGCYFEN
HKFSKNFKNEILFHYKKNKIGTNMCITQFFYNFNTIKYYINIIKKTGISKNFILGIISKK
NIKDILNYTNLCKIDIPIWIIKNYKEFNIELFFVKNLKKYKNLHFYTFNNINLIKNYFK
>A0A2E8QP61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacter sp|TrEMBL
MTPVTGDPGQPLAILEGHVSAGRLERVLRSGKFAVTAEIAPPDAADAEAVYERASVFDGC
VDAINATDGSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVTN
ILCLTGDGVQAGDQPDAKPVFDFDCISLLQTVTAMRDEGEFLSGRKLTTPPRVFLGAAAN
PFGPPLDYRPIRLEKKINAGAQFVQTQYCFDLVRLREYMSRVRDMGLTERCYILVGVGPM
PSARTASWIRDNVPGVHIPDAVIKRLLGAENQKEEGVRICVEMIQAVREIEGVHGVHIMA
YKQEERVRDIVEESGVLEGRIPWYPGVSNDQQGQQT
>A0A533TC58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium sp|TrEMBL
MLVKEILGSAAKPVFSFEFFPPKKDEEWETLFKTITALSPLNPSYVSVTYGAGGSTRSRT
HDLVTKIQQETGLTVVSHLTCISSDTGETGTILQNYRENGINNLLALRGDKPAGVASIED
AIKDFPYAIDLVRFIKTNYPDIGVGVAGFPEGHPETPNRMKEIEYLKEKVDAGADYIVTQ
LFFDNRDYFDFVERCQIAGITVPIIPGIMPINTKKGMIRMSELALGARIPAPLLRKVLAA
ANDAEVASIGIEWATMQVQDLIDHHIMGVHFYTLNMADATLKIFKNLHP
>A0A1Z8Z5G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium TMED82|TrEMBL
MELSVEFFPPKTEEGMSRFVNAAKDLSKVNLNYASVTYGAGGSTKSGTMSAVDQLNGLFQ
SAVPHISCVGSSEKQAQSLLDQYVAKRLNHLIVLRGDLPSGFGGSGEFQYASDLVRFIRK
KFDSHFRIEVAAYPETHPQAKSCRDDIENFIAKVEAGADGAITQYFYNSDAYFRFVDEVG
KFGVKIPIVPGIMPITNYTQLVRFSDACGAEVPRWIKNRLAQFADDSKSIKEFGLEVVSN
LCDQLVTAGVPGLHFYSMNKSNMTLEILKNVGLVK
>A0A1U7L7Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricimonas synergistica|TrEMBL
MKVIDILNKSDKAAFSFELVPPLKGGDINKIYEAIEPLIALAPPFINITFHRDEVVYREY
PDGTIKKVTVTKRPGSVALAAAIMKRYNVDMVPHIVCGGATRHKIENELIDLNFLDIENV
MALRGDPIPGERFFTPEEGGHQYSCELVEQITRMNHGQYLDDTLTEAVPTNFCIGVAGYP
EKHYEAPNQACDIENLKKKVDAGANYIVTQMFFDNSKFFQFVDKCRAQGINVPIVPGLKP
ISTFKHLEMLPRTFSIDIPHELVKEIRSCKNNKEINQVGIEWCVAQSKELIAHGVPAVHY
YTMGKSENIQEIVKQVF
>M6BWF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira borgpetersenii serovar Hardjo-bovis str. Sponselee|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTQDGDLKLMGTVKELARLDPDFVTVTYGAGGSTRDK
TAQILSEISKNYSFPTVSHFTCVGANQDQIFKTLKEIRSSGIVNLMALRGDPPKGEGKFK
KTEGGFENATELISFIRSEKLDFCIGGGCYPEKHPNAKSLEEDVRNLKRKVDAGTDFLVS
QLFFVNSIFENFLNLVRKADIRAPVIPGIMPITSFSQIERFRSIAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSIKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A099RQW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. HMP271|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLASYHPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLDIYRKAGIRRIVALRGDLPSGMGLASGELRHANEL
VEFIRSETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKAQAGADSAITQYFFNADCYFY
FVERVRKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIDSIQAFG
EQVISEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLPRQA
>A0A5S4GAT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea zeae|TrEMBL
MALGRPSIRPDRVPTVRELLAGGGRSFSFEFFPPKTDEGERQLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERIAHDTTLTPVAHFTAVNHSIRELRHLVGRFADAGVRNILAVR
GDPPGDPGADWVQHPEGVLYAEDLVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTEYFVR
KCRAGADYAITQMFFQADDYLRLRDRVAAQGCETPIIPCIMPVTQMSTIARSEQLSGAPF
PPDVAARFEAVADDPAAVRRLGIDHGAELCQRLLDEGAPGIHFITFNRSSASREVFQRLE
PAQLSA
>A0A4Q2JF11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenobacter cavernae|TrEMBL
MTLPISIELYPGVVPAAAARSAELIARLAPLSPAFVSVTDGAGGISRAAGLALSDALNAQ
GFAVAPHLSAAGLDKAIATERLAEFTKRKAKTLFVLRGDTPSGMGERGDFRYASDLVRFM
REALGDDPDILVAAYPEVHPQAANAKSDLAALKAKQDAGATGAVTQYFYNADAYRYFTDA
AVRAGITLPIVPGILPLTRASMARLAEVRGVELPRWMKRTLDACHGDASALASFGREAGA
RLVSQLIDAGAPGVHFFAPGAAEIEMAGHIVADAGLTPRAAA
>A0A381W8D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MGNVNFSLEVTTRTDLSSLPNLKDIYITFLPSSDYKDVIKQTRSLVSSGYNAIPHFPARS
IVDQNMLRDYVDQVKDAGVNQVLIIGGDRDILGDYHCSLQLIETGLFDNFKIGIAGHPEG
SPNMSDDVIEEAMKSKSKFADYIVTQWTQDTEALSNFISKAPLPVHVGLAGPASIKTLVK
FAGFVGLKNTLNFAKKNASKIFDLLTIQTPDDVIQELKNKVENFHIYAFGGIKKTNEWLQ
KENYYV
>A0A838FTZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MSEFTITPVAGQVPAAGNGQNARDALNAALRAALRHPRFEVLPLVGTAELVEQHLSHSIP
VTVTASPRQGLEPTLVVTEALARLGFPAVPHVAARLIVDESHLVEVLHRLDEAGVRDVFV
VGGDGDRPVGCFRDALTLLTAIQRLRNCGVGASLEQVGITGYPEGHPLVSDRELIESLAA
KQSLATYAVTQMCFDATAVSRWVSRVRRDGITLPVYVGVAGKIDRRRLMRISARIGLGDS
ARFLRKHRHGWTRLLLPGIYNPDRLVRELGADLARPSRGVAGLHVYTLGAVAATEQWRRQ
ALVRLGDDGLR
>A0A382EG35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKIADLYQKKTFVFSIEIFPPKNTESLERLKLRLEEFKSYHPDFISVTYGAGGSTRENTH
ELASFIQNDLGIETMAHLTCVSHTRQEIEEVLEQFHQSGIENLMALRGDPPSGEKCFQRP
SGGFAYAVELIQAVRSLNGFCIGAAGYPEGHVENPDKEADLRHQLAKVEAGADLLVSQFF
LENEHFLKWRDRLRREGVEIPIIPGLLLPSSPDALFRMEELCGVLIPLSLRQKLERYAGD
PNALKEIGWLHLAEQTEALIGEGIEGVHLYALNRLETIRRFSELIQPSLSFQETYPENPT
RPSLAEKTEMPLTT
>A0A382QL90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MSIPETNNQAYTYRPGELLPELEGHISRGRFERVLRNGDFAVTAELAPPDSTDRNEVFEQ
AALFDGCIDAINATDGSGANCHMSSVVVCALLSYIGYSPIMQISCRDKNRIAIQGDLLGA
GALSICNVLALTGDDVSVG
>A0A381XJH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MIKGISFEFFPPRTPKLEAKLWQSIERLTPIGPKFVSVTYGAGGSTRTATHKIVKTIISD
TDLNVAAHLTCVSASKEEVDAVIDDYKAVGVNHIVALRGDMPDMGLFQPHPGGYSSSVDL
VEAIKKHGCFDVSVSAYPEKHPESSSFEADINLLKAKIDAGADQAITQFAFDTDVYASFR
DKVIADGINIPVIPGIMPTTNFKGVQRMAEKCGTNIPNWLISKYIGLEEDLERRQETSIN
VAVDQCRSLISEGFDRLHFYTLNQHQIISKVCRILGLGSGRELAEEDLPVLNNGERS
>A0A381WNI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKNFRTALNTQDFVITSEIFLRPETNSNSIQIQADILRDYVDAILITDNQSGRVHMSSLA
AGVLLLGVGVDPIVQLSCRNRNRISLLSDLLGCSALGITSLSLIRGDKVPDDFQPRPKAI
MDVTATELIRIANTMKNDENIDSSRNFFLGGVVTAHAPKSGWPAKNITEKVNAGAQFVFT
HTCLDMDLVRIYMKRLAEIKLLWQCHVVVGIAILNSAEDAQWVRKNRPNVIIPNDIITRL
SNAKDPEKEGIAICVEQLEELSTIPGVSGAHIIAPEKLTNIPVAVSQSDTYKKNPQ
>A0A381R1N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MTRPDDVPAQLVRDLYSGRQLSERPVISFELFTPKTVEGDRKLVENTLPELIKLKPDYVS
VTYGAGGGTRTKTLTLVDLIQRRYGLTAMAHLTCVGHTESDIAGILKEAKSLGIRNILAL
RGDPPVGQETFIKHENGFEYSYQLIQFIQRAGTFCVGTAGFPEGHIACRQGKLVDWGYLK
QKVESGAEFILTQLFFDNADFFRFRDHMEQKLGVTVPICPGVLPILSAKQIARFTKLCGA
RVPDKLEAKLESLAGDDDGARAFGIEQATEQCEELIREGVPGLHLYCLNKTHSVSAILRN
LNLTDT
>A0A7L5Z1V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MAATAFRIPDAFASGARTFSFEFFPPKDAEGRRLLWRTLRELEPLQPSFVSVTYGAGGST
RDLTVAITERIAIQTSMSPMAHLTCVGHTRDELRRVIGSLAAAGVRNVLALRGDPPGGPT
APWEPVEGGLSYASELVALTRSLGDFAVGVGVSPSGHRASLSLEHDAQVLKQKQDAGAEF
AITDMFFDSDQYFALVERARAAGVTIPLVPGIMPITNIGQIERMAEFTGAPVPDQVVKRV
VRFEGDPKAVRAEGILVATELCDQLLAGGAPGLHFFTLNRSKATREIYQGLQVTA
>A0A7W1JJX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MRDATTCTEAGPARVGSAQPWLVAALRRPRYEVLPLAGTADRVVEHVPPTIPVTVTCSPR
RGLEATLRLTETLSGRGFSVTPHLAARQVVDEAQLTEILHRLDAAGVRDVFVVAGDDERP
AGEFADSIDFLRSLDRLRRGGGAPVPHRLGVAGYPEAHPLVGNDELMEAMRAKQPHAAYL
VSQLCFDASAISSWLADVRYAGVRLPLHVGVAGAVDQRRLLRVVQRIGVGPSARFLRKHR
YGLLRLLRPGGYRPDSLVRAMAAELSDPTRGVAGLHIYTLGDVAATERWRQRALDRLSDE
DGHA
>A0A381YJN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKISEKIADYIAQEKTFYSFEFFPPKTDFGRDNLYSRIDRMASLHPAYIDVTWGAGGSTA
DKTLEMCKTIQKYFGLEVMMHLTCTNMAISSIKKILIEAKENDLFNILALRGDPPEGSLT
WEKHADGFRYGVDLVRYIRKEFGDDFFLGVGGYPDGHQEQTDIDVDINFLKEKVDAGSDI
VVTQLFYDVDKFLLFRDKCIKAGIKAPIIPGIMPIHNYGRFLKFTQFCKLSIPDSVSTQL
ESIKNDDSSVINYGIDQATAMCKKLIEEGVPGLHFYTLNLEHSVSKILKSLDLVSSRGIS
KELPWRQSTLGDRKTSED
>A0A382BJ09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MTKVINAFENRKSKPLIISDFSPPKTLKPGFLNDVRNLNVDFIFVAYNPGRSVRIESSAL
AHVIVQETGKEVIFSMVTRDMNKLALQSHLLG
>A0A1Q8I7V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. M8|TrEMBL
MDRLRAPRGARIPFSVEFSPPRDADAEARLWRAVREFERLGPAFVSMTYGAGGSTRDRTV
RVTGQLAQETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWTR
HPEGLEYAEELVRLVRDLGDFHVGVASFPEGHHRSPDLEHDTRYLVHKLRAGAEYSITQM
FFDVEDYLRLRDRVVAYDPEQGAKPIIPEIMPITSLRTARRSLELSGSRLPAALEERLVR
AAGNGPEEDRAAVREVGIDVATEMAERLIAEGAPCLHFITLNFARATREVLARLGIAVPT
AV
>A0A4Q2XMF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MHISDILASTPTTLSFEFFPPKTPEAVERLYETISQLEPYQPSFVSVTYGAGGGTREMTH
DLVVRLKQTTELDPIPHLTCVCHQEGEIAEILERYAAAGVSNILALRGDPPTDRAGYDRS
KDAFKYASDLVAYIRRFNDSKAHPDSRGFGIGVAGFPEGHPLTPNRLVEMDHLKAKIDAG
ADYICTQLFFDNHDFYDFRER
>A0A4Q2XJ54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MHIRDILSDSKPSLSFEFFPPRSAAAWEELYQAIRELEPLQPTFVSVTYGAGGSTREMTH
DLVVRIKQTTSIPPVPHLTCVGHREHEVLDILRRYAAAGVSNILALRGDPPKDRPDYDWS
EGDFRHAADLVRFIKKFNDSGEHPDPRGFGIGVAGFPEGHPTTPNRVDELDFLKAKIDEG
ADYICTQLFFDNHDFFDFRDRCSIAGINVPIIAGVMPVTSLSGMKRMAELAAGARYPAKL
LRALGRAQSTPQAVERVGIHYAAEQCAGLLNEGVDGIHFYTLNKSHATREIYHSLGLTSA
ATAS
>A0A521FHU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus laeviglucosivorans|TrEMBL
MTTPAISFEFFPPKNLDQSFKLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETLQIVADYAAAGVHEIVALRGDAPQGQDRFTPHPNGFANSI
ELIEAIAARGDMTIRCGAYPEPHPESPDTAADVAWLKRKSDAGATSAITQFFFDADTFFR
FRDQAERAGVTARILPGILPIQSWAGTRRFAERCGTSVPQWAEDAFAAAGKAGEAQLALD
TCVKLCEELVAGGVDNLHFYTLNKPELVLKVCAALGVAAKSELVA
>A0A1G7JBT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. PDC64|TrEMBL
METPNISIEFFPPKTPEGADKLRVARQKLAELNPKYFSVTFGAGGSTQHGTLSTVLEILA
EGHDAAPHLSCVGGTRESIRAILQEFKEKGIRRLVALRGDLPSGYGGAGELRYASDLVEF
IRQETGDWFHIEVAAYPEMHPQAKSPQDDLQAFARKVQAGANAAITQYFYNPDAYFQFVD
NARKLGVDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWIRLKLASFGDDSASIKAFGLDV
VSSLCEKLLAGGAPGLHFYSMNQAAATTAIWQRITAA
>A0A0R0A282|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas panacihumi|TrEMBL
MTPISFEFYPPKTDEQRTQLDRTAARLSTHGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
RFDAAPHLSCVGGSREEIRELLKLYRALGCRRIVALRGDLPSGMGHPGDLRYASELIAFI
RAEHGDAFHIEVGAYPETHPQAADALTDLRHFKAKVDAGADGAITQYFYNPDAYFAFVDA
VRKLGVEIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIAKRMQAYGDDVDAVREFGADVV
AALCQRLIEGGAPSLHFYTLNLAKPTQQILQRLGR
>A0A3D4KIF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp|TrEMBL
MTKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRGRTLDIVQALCA
RGDTDIAPHMSCIGDDKSQIAELLDLYKSLGITRLVALRGDLPSGQVGMGELPFALDLVK
FIRKHSGDHFRIEVAAYPEMHPQARSFEFDVDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTVAQPLVAGIMPITNSSNLVRFADSCGADIPRYVRKRLADFGDDRAAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVEALGLIA
>A0A2E0EKU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MHHTTNLSLSFEFFPPKSAAGEAALWECIQQLSALKPDFVSVTYGAGGTTRDRTHRLVKR
IREETELEPAAHLTCVGANRDEIRQIAESYWNDGIRHIVALRGDPPAGEREYIAHPEGYA
YADELVKGLLECGDFEVSVAAYPETHPQALSRDEDMRHLKRKMDAGASLAISQYCFDMDY
YQAFLKKLPEYGIDPHKVVPAILPIGNFTQMAKFSKMCGASVPEWLCQRFEDVDPQSELH
AQLAVATAYKQALDYLQTGASRLHFYTLNRADLVLAVCRLLGIRPS
>A0A2B4SHA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stylophora pistillata|TrEMBL
MASPDVNSYEEDLKHLKAEVDAGADLIITQMFFEVKTFLKFVDDCQRNRINVPIIPALFP
IQVFNKFYYITHSAHGQDENFNSLRQLKRLSRVEIPQWLLDKLAPIKEDTTAVMNYGIKY
STEMCKQLFGSGHVHGVHFYTLNRETSITEILEKIGMSYKEDELDSASMRRLPWMPGPAQ
ARRGQMELVRPIFWTSRPRSYMIRTSNWDEFPNGRWGDSSAASFGELRDYHLVLLGTNES
KEELLNMWGRELNSPEDVFEVFVCYLTGKENRHGYKVKEIPWNQDELASETLPFVDKLAH
VNKHGVLTINSQPNVNGAPSTDPVSGWGRPGGYVFQKAYLEFFTSEEIAMCLYEVLQDYP
MVNYHIVNFSGKEDVTNANVYSSNAVTWGVFPGSEILQPTVVDPIAFQFWKDEAFALWKH
QWGHIYSDKSLSRGIIDTIHDTYYLINLVDNDYVAGNILFDILDIVLKKLGKI
>A0A3G2WA13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis pv. commiphoreae|TrEMBL
MISTDTPNFASTVTEAYSLEVSAKDVGALTNAAPRILPGCAMFIPYLPGQNQAVRLAAAQ
MVRSLGFEPVPHLSARRIGSLGELQACIARLVDEAGVTRCLVIAGDPSTPKGPFPDSVSL
IETGVFERSGIRTIAVAGHPEGHPILRTTEQWEVLERKCRSIQERGMAPLIVTQFGFDAD
IVVTWLEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLASRLTEAHGDVRLHLFPFGGIAQSVEWVAHYRSRASQQDRMRSVRADQA
>A0A7Y8EJX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas yamanorum|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNAESYFY
FVERVQAMGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A3R8PY02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora rhizosphaerae|TrEMBL
MPFRSTEEQVLAHVPCDVPLTVTTTEARGLEPTIDLAVRLTKNGYSAAPHLAARLVRDRA
ELDEIAGRLLESGVERLFVIGGDAAEPAGEFPDAESLLLALAEGGHEFAHVGIAGYPEGH
GRIPAEVISEALRRKADRVHEIVTQLCFDPAATTRWATGLRASGITTPVRVGIPGKVNRQ
KLVRVSAGLGLGQSARFLAKQSGVLWRFFLPSGYRPDKLAAAVADQITEPGNAINGVHVF
TFNDLERTERWRREALTRLHA
>A0A4V2LKZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4635|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRAVHQDLQQLNPEFFSITYGAGGSTRERTLAAISDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDQDIQRFAEKVHAGANAAITQFFFNPDAYFYFI
ERIAKLGVHIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSKSIQAFGHE
VVVKLCERLIAGGAPSLHFYTMNHIQPNRQLVTDLGLA
>I9A1F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. QA3|TrEMBL
MTAVRSVSAKPATMGEFLASGRPSFSFEFFPPRTPEGERHLWTALRRIEALRPSFVSVTY
GAGGSTREGTIRVTERIATDTTLTPIAHLTAVNHSVAELRQVIGNYAGAGVRNVIALRGD
PPGDPQGTWTPHPQGLKHADELVRLVKSVGDFCVGVAAFPDKHPRSPDFDTDARYLVGKF
DAGADYAITQFFFGADDYFRLVDRVRALGCDKPIIPGIMPVTNVAQIVRMAQLSGAAFPP
ALAARLQAVADDPAAVRAVGLEVATELSRRLLDGGAPGLHFITLNRSSATREIFEAVR
>A0A517R3Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium Pan189|TrEMBL
MRIAEMYRDGGFGLSIEIFPPKTEVGENNLKRTLQRVRHFEPKFISCTYGAGGTTRGKTL
EWCRTIIEECNLPATAHFTCVGSTREELLQWLEEAAEVGVQNIMALRGDAPQGQDKFEAI
EGGCAYANELVELIRANHPEFGIGVAGYPEKHLEAPSLDVDLQNLKRKVDAGADAIFTQL
FFVNDSFFRFRDQARAVGIDRPMIAGIMPITSFERIKKITAMCGAIFPVDLAKSLESVKD
DDEAQFEIGVDHAIKQCRELIEAGIPGIHFYVLNKSQAAERILGALDVAPAIPAGV
>A0A0J1AA77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii MRSN 3527|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLDKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A2T2WD64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfobacillus acidophilus|TrEMBL
MKELREVLGRELLIEDGAMGTWLLSQGASASQLPMVPLSQPDLLLRAHLDYLKAGARLLE
THTFAANAGKLGALGISADVAELNRRAAQIARHARDIHGASAYIVGSMGPLNARVESRIM
PGISMAEAQRQYGEMVAGLLAGGVDGFIVETMSDMLAIQAAVAAIRRESDLPIIVSLTFS
RLGTTLYGFTPEEVVEELAHLPGGPPQMVGANCGTGPALLLDAAWRMADVAKKYGMALAV
SPNAGEPYVIDGHVAYPASAEYMAALAPAFKAAGCLVIGGCCGTTPAHIQAMAERVKDEA
PSVADWRPLPVVREEAPIAEPSRTHETLLDLLDTRFVVSVELDPPRSPNLERFLESARAV
AKAGAPVINIADSPMARVRLSALAAARLLQESVGVQSLLHFTTRDRNLMGIQSDLLGAYA
LGVRNVLALTGDPPGIGDYAHATAVYDIDSVGLVRVLHSFNQGQDALGQPLGTATAFAVG
VGLNPTAEDLDREIQRLQQKIEAGAQYCLTQPIYSADQLYRFLDRWSGSLPPLLLGIMPL
VSYRQAMYLHHEVPGITIPDAVLAAMESSLDAMQTGTELAIDLLNQVSSLVRGVYLVPSF
NRVTPLIPILEALKRLTGATSTS
>A0A378ZDP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus thiaminolyticus|TrEMBL
MKDLRQVLQGEIIVGDGAMGTYLYQLGYPVGISYESLNISEPERIRDIHREYVSAGARLL
ETNTFTANREKLSKHGMEKQVKAINRAAARLAREAAAGQAYVVGALGSIRAGKRENIETE
QVKRDYTEQLSALLEEGVDGIMFETFYDMEEMKLAVQIVRALDDRIPIICQFAVEESHRT
KDGLRLLDAFRLLREEGADIVGLNCRMGPNGLMRAMEEVTGRLALPMSAFPNAGLPDYVD
GRYNFVATADYMAESAVRFAELGARIIGGCCGTTPEHIQAIAQALADAEIPVLPTLAEEE
AQAQAVPPLEIGELDAAPVSGQGKAASGPSLVDTVRERHTVIVELDPPRDLDIAKFMLGA
QALKDAGADALTLADNSLAVTRMSNLALGYLALDKVGIRPLIHIACRDRNLIGTQSHMMG
LHALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEIIRMIKQLNAGLAFSGKVLKQRANF
VVGAAFNPNVKHLNKAIERLERKIEAGADYIMTQPVYDAALIERIAEGTKHLKVPVFLGI
MPLASGRNAEYLHNEVPGIHLSDEVRERMKGLEGESGRREGVAVAKELLDVAMKHFNGIY
FMTPFMFYEMTAELTEHVWQKAERPTAPLYRHT
>A0A7X8HGR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierellia bacterium|TrEMBL
MFIKDIFEKKKFVFSFEIFPPKATSSIDTVYKTLEALSDLRPDYISVTYGAGGGSNSNKT
VEISSIIKNRYDIESLAHLTCIGSTKEEIKVVLQELKEEGIKNILALRGDIPLDQEVCGE
FQYASDLAEFIMENDKFDLGGTCYPEGHYSSKNIEEDVKNLKYKIDAGVTHLTSQLFFNN
DYFYNFLDLAAKYNINVPIQAGIMPLTNIKQIEKISALSGSKVPEKYVRAMEKFAHDKDA
MADAGMAFATEQIVELMTMGVDGVHLYTMNNPYVARKTHDNIISIIHAMNRL
>A0A5M9UEB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. UASWS1643|TrEMBL
MKADLRKVMQERVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQISALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFAELGARIIGGCCGTTPDHITAMKEALADYIPSPILEPDPSE
SKPRIVLHEHVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLEKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFIGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A3D2RS51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MRFRDFFKGKTRPVISFEIYPPKTKRGLHALKSRLLPKLIELGPSYITVTYGAGGSTQGE
TLEIASTVKNELGLEAACHLTCVGASKSEIDDIIGRIRTEGINNIVALRGDPPTGQDQFV
AHEEGFNHANELVEHIRATEDSNSRVGLAVAGYPEKHLEAESLDVDIENLKRKVDADADI
VITQLFYDNDAFYDYRDKVAAAGIDIPIVPGLMPIQSRSQVQRIASLCGATLPKNLLGQI
EDAGDDDEAVKVIGTEQCTAQSQGLIRNGAPGIHYYVLNRSPQIRRIVRAL
>A0A2K8K5W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carsonella ruddii|TrEMBL
MKNISFEIFPNKNIKESIKFVKIIEKKKPVFISITCSKINNFDFVKTIKNNTNIKIIPHI
ICDNLYNIVLKIINFIKIKIFNFIIITGDNISNNSFLTIKKIRFLFGHIIKIFSGSYLEE
HKLSSNINKEILFIYKKKKIGINLFLTQFFYNFNIINYYLNKIKKTYINKNFIPGIFPKK
NIKEILLFINKCKIEIPIWIIKNYDFINIKNYLLKNLNIFKHFHFYTFNKINFVDYYLK
>A0A5Q4GFG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenzhouxiangellaceae bacterium|TrEMBL
MVKRPISFEFFPPRNDAQAESFRAARDRLAALQPEYMSVTFGAGGSTRSRTRTTVLELQR
ETGIDAAPHISCMAEDEAGIRQLLDAYKEAGIHRLVVLRGDRPSGGASGVFDYAVDLVRF
IRRSYGNHFHIEVACYPEHHPESTSPERDLHYFRDKVEAGADGAITQYFFSPESYFRFVD
DARALGVEIPIVPGIMPITNYASLARFSGICGAEIPLWIAKRIKAWEEAGERGSLLSFGE
EVVSRLCQRLLEGGAPGLHFYTLNRARPSVAICRNLGLAPES
>A0A4Z0LKQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tabrizicola sp. WMC-M-20|TrEMBL
MATPRISFEFFPPQTLDASFRLWETVQALAPMQPEFVSVTYGAGGTTRKLTHEAVTAIGK
NYGLNVAAHLTCVDATRAETMEIAAAYADAGVTEIVALRGDAPKGAERFTAHPDGFASSV
ELIEALAATGKFKLRVGAYPEPHPDAADTLADVRWLKRKIDAGATSAITQFFFDADTFFR
FRDLCVKEGITAPIIPGILPITSWAGAKKFALRCGSDVPARLDEAFTTAARDGREELYAL
AHCTQLCDNLLQGGVEDLHFYTLNRPHLTREVVRALGIQPELVPELVLEKVA
>A0A660Y326|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MDFVRKVDGEVKVLAGIVPVVSARMAEYMNENVPGIFVPQDIIDEMKGVPKGKRVKKGIE
VAARIIRKIKEEKICDGVHIMFIGREERIPEILEAAELL
>A0A552R364|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 130|TrEMBL
MALGTPSTRTDHARTVREMLATGETSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATQDIAAESTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGPWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPERHPRSDDWDTDVRHFVD
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCDTPIIPEVMPVTSVRQLERFPQLSNATM
PEDLKDAILAAKDDPAAVRSIGIDFATRFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A496SNE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MSRLQESLEQGEFVVTGEIGPPKGVNIEAALKDASYLKGRVVAVNVTDNQSSVMRLGSLG
VCVRLLQEGYEPIFQLTCRDRNRLALQSDVLSAYILGIRNVLALTGDHPALGDHPGSKPV
FDLDSVSLLVAIRSLMEGKDLAGEELDGKPSDLFPGATVTPGADPLEPQLIKMEKKIEAG
AKFFQTQAVYDPKVFEKFMNQASKFGVPVLAGIVLIKSPAMARYMNENVPGVFVPDSIVK
PLSEVSRKDRPKKSIELMAGLIRELKPMCQGVHIMAMGWERYVPELLDACEL
>A0A2G4H583|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilia bacterium|TrEMBL
MNATDNTSAHAHASNVAMAIAMQRVGVEPILQVVCRDKNRIAQQADIMGAALHGVENICC
LTGDDVTAGDEPEARRVFDLDGPQLIRLANSLKEGRYLSGRKIDPAPSLVIGAVENPATH
PLDYRAQRAAKKILAGARFLQLQICYHPDRLEAFVAALHANGFSERCAILPSIVAVKGAG
PLKFMHSSVPGIDVPAAVISRVADAADSAEEAYQLVLEQCQHALSLPGVRGLHLTDFRKD
GSMGRLCADLGIRPRSERESRANDFALAN
>E9XUY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli TW10509|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4R3VRS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium alimentarium|TrEMBL
MKIIDHIKRADGNPLFSFELLPPAKGQGIQSIFNTMDELMEFKPPFIDVTYHREDYLYKQ
HSNGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLDFLGIDN
VLLLRGDARKGDPDFIPTPGGHAFATDLLQQVVDMNNGKYLHENIENSSKTDFCIGVAGY
PEKHFESPNFNTDFKWLKKKVEMGANFIVTQMFFNVEKYKEFVTKCRENDIHVPIIPGLK
PLTSKKQLITLPKIFHLDIPEDLSDAVDACKTNAEVRQVGEEWLVQQCKELIAFGAPVLH
FYTMSNPGPTKRIVEKLA
>A0A2V3VKM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogracilibacillus auburnensis|TrEMBL
MSLLTDLKKQILIADGAMGTILYSHGVDRSFEELNVTHPEQIQNVHEAYINAGANVIQTN
TYGANYIKLARYGLEEQVKKINQKAVQIAKLAAKGKVHVLGNIGGIHGAQTLIETEEEIK
RSFREQLYCLLLEGVDGLILETYYNLDELKTVLKIAREETDVPIITNVSMHEPGVLENGL
ALTEALKQLEALGADVVGVNCRLGPSQMVTSLESVPLLEKAYLAAYPNASLPAYRDGVLF
YENEPDYFQTCARDLRNQGVRLIGGCCGTTPEHVRALAEGVKNVAPLEEKVVKQEELVEI
LPERKHREKTIPELAKERPTIIVELDAPKHLDITDYVEGAKALKEAGIDAITLADNSLAT
PRISNVAIATILQELGIKPLVHLTCRDRNLIGLQSHLMGLHTLGISEVLAITGDPTKIGD
FPGATSVFDVNSFKLIELIKKGNNGISFSGKSLREKTSFSVAAAFNPNVANVKRAVQRLE
KKIASGADYILTQPVYSNEKMIELKEATAHIEAPIFLGIMPLTSTKNAEFLHNEVPGIKL
TDEVRARMKAAEGNRALSTRESIEISKELIDTAIEHFNGIYLITPFMRYDICVELIHYIH
EKNALVKTNEVTI
>A0A2W6C400|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dormibacteraeota bacterium|TrEMBL
MDRLEELMQRGPVLFDGAMGTELNARGVAVGHCLEEVNLVQPSLVLAVHRDYIAAGAEVI
ETNTFRANRFGLGDFYLEGKVREINLAAARIATEARNNSGRPVLVAGSMGPLGRPIEPVG
AIKRSSAERIFGEQVQALAEGGVDMLVLETFTALGEMETAVQAARATAPQLPVVAHMSFD
DQANPAQAAAALVRALEPLGVAGIGANCGSGPYAALEVTTHLAAAGARNISVMPNAGLPE
RVGGRLVYSTGPEYFAELAERLVAAGARMVGGCCGTGPRHIAMVRDRLAETVESPRSSVR
RRRPAERSEGEAAPRSRLARELAMGRFAVSVELTPPRGIDPRRMLEGARLLKEAGVDYAN
VTDSAMARLRMGVISCAALVQQQVGLEAIAHFTCRDRNVMAIQSELIGAHALGIRNILAL
RGDPPRVGDYPNATPVWDVNAVGLITILANLNQGLDANGTPIGERASFLVGAAVNPSADD
PEKEVRLLRRKLAAGADFIVTNPIYEAAALERLRAIVADSAVPVLVGVLPLVSVRQAEYL
HNEVPGMAVPTAVRQRLERAGDRAPELGVEMAVDFLDAARAHVQGAYVIPAATRYDLAAR
VVTRTRELVG
>A0A8E2H9L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. 63-713|TrEMBL
MNASYEALNEARKALDAPLFAGLPGDIRVSFEFFPPKSDAMMAQLWEVVETLAPLDPAFV
SVTYGAGGTTRDRTHGTVARIISEARLPAAAHLTCVDASKAEVNAVAEAYWEAGVRHIVA
LRGDMGQPGAPFVPHPQGYQNAADLVAGLKRVAPFEISVAAYPEKHPDSADVDADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDRLAAAGIDAPVLPGILPVSNFAQTRKFADACGAA
IPAWMEGLFAGLDTHPPARALVAATIAAEFCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GVRPNPVRTVQEKAA
>A0A7V6X396|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MYIKDIFAAKKGPVLSFEIFPPKKDSPLETIYTTVESLKHLKPDFISVTYGAGGSSKDRT
VEIAALIKKKYGIESLAHLTCISSTKTEIENLLSDLKNNEIKNILALRGDLPQDKNFKFP
SPLHYNYAQDLIQQIKTENNFCIAAACYPEGHIACPDLKQDIRYLKEKVNKGTDFLITQL
FFHNEYFYNFMNEIRKIGINIPVTAGIMPLLSKKQIEHCLTLSKATLAPKFTRVLEKYGD
QPTILPEIGIIYAVDQIIDLLAWGVDGIHLYSMNRPEIVLRIVKEIAHLF
>A0A849MVE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseicella sp. DB1501|TrEMBL
MPAARPIGPEPEGRAAAAHGTLQRWLTGPRVDGLPQLTARPAPALSFEFFPPRTEALEAQ
LWACIRRLEPLAPRFVSVTYGAGGTTQARTHATVARIVRETSLTPAAHLTCVGASRAEVD
EVARAYWEAGVRHIVALRGDPPAAAAQYEAHPEGYAYAADLVAGLRRIAPFEISVAAYPE
IHPTALSAEHDLDNLKRKIDAGATRAITQYFFDSDVFLRFLDRALAAGITVPIVPGIMPV
SNFTQMRKFSAMCGAGVPDWMGRLFEGLEEDAETRRMVAAVVAAEQVRLLQANGVDEFHF
YTLNRPDLVYAIAHILGARPRRPG
>A0A1E1K253|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhynchosporium agropyri|TrEMBL
MHIKDMLAEAERSGQPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVSVAQSHHGLETCMHLTCTDMGQDMVDAALRDAYKAGCTNILALRGDPPREKEK
WVATEGGFQYAKDLVKHIRETYGSHFDIGVAGYPEGCDDQDDPELLLEHLKQKVDAGATF
IVTQMFYDAENFIDWIHKVRAKGITIPIVPGIMPINTYASFLRRCNHMGCRIPPEWSEAL
EKVKNDDSAVRNIGTGLVAEMCRKLLAAGIHHLHFYTMNLAQATRMLLEELNLTPSDQRP
RKQALPWRQSLGLGRREEDVRPIFWKNRNKSYVTRTQNWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNRKLWGEPKSIKDIAEIFVKYLENGVESLPWSEEPISSEADSIKSDLIA
LNRRGMLTINSQPAVDGAKSSDPVYGWGPNNGYVYQKAYLELLVSPTLMAQLITRIELEP
DLTYYAVNRVGELKTNASGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AKCYSALSPSRQLIENLMDTWYLVNIVHNDFHQTHGLFPLFDGLELKDIDVPFSSSVNGG
DANGADTNDVHTNGVNTNGVHINGVNGIKPEGKENIHLTNGAPVKVSAAN
>A0A7C4B289|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
ADRDSIGAMLDSLDSKGIRNILALRGDLREGMDHSSAFSHYRHASDLIKDIKKRNVFTVG
AAAYPETHMESGSPEEDMRYMLYKEELGADFFITQLCFDKNALIGFHDRARKAGVRAPII
TGIMPVLNPSQITRMALLSACSIPAQLSRIISRYGANAEDFKKAGLDFAIDEIEFLIKNG
VTKFHIYTMNRPEAARQIIEGSSLNA
>A0A7C3UM41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MFLRDLFKQGKFVITSEIGPPKGCEIEETLKEAEMIRGKVDAINVTDNQSSVMRFGSLAT
CHLLIEKGFDPVFQVVCRDRNRIALQSDILSAAGLGIKNLLLLTGDHPLLGDHPDAKPVF
DLDSVSLIHVVKQLENGTDMMGNKLVGEPPKFCIGAVVSPCAEPLDPQLFKMEKKIKQGA
EFFQTQAVYEPDKFAKFMDKVKSWNIPILVGIVILKSVGMAKYMNEKVAGVHVPDTLIEE
LKKDKEKTKSGQTGVEIAARLIKELKPLCQGVHLMPLGWTDKVPEILKLAEL
>A0A355E7F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MRIPDLFRGGEPVFSFEFFLPKNESDLARFKETVRALKLLRPGFVTMTYGAGGSARERTI
ETAGAIKNELGLETAAHLTCVAHTPAEIAALLGRIRSFGIENIVALRGDLPKDLAPGAGP
GPIPHAADLVRLIRSHGGSSVAVAAYPEKHPESPSPEEDLRRFREKTEAGADWAITQLFF
DNASYFDFTARARAAGIAIPIVPGIMPVTNFKQLQKFTAMCGTRLPEPMLRDLAPIADDP
EAVLRYGIDYAVRQCRELLQRGAPGIHFYTLNRSHATATILERLREGG
>A0A369GKQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps camponoti-leonardi|TrEMBL
MHIKQMLLEAENGHQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQSVCGLETCMHLTCTDMGLDKVNQALSKAYKAGCTNILALRGDPPRDQKQ
WTATEGGFQYARDLVKHIRDTYGNHFDIGVAAYPEGCDDNKDEDQLLDHLKEKVDMGASF
IVTQMFYDADNFIRWVGRVRDRGITVPIIPGIMPIATYASFVRRANHMQCTVPPRWMDAL
EPYKNDDVAVREIGKTLVADLCRKLLASGIVHLHFYTMNLAQATRMVLEELEWAPCPERP
LHHDLPWKQSKALGRRHEDVRPIFWSNRISSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGAPTTVRDVADTFVRYLDQEIDSLPWSESPLTGEADVIRPSLKA
LNERGLLTINSQPAVDGAKSSHPVHGWGPSNGYVYQKAYLELLVPPDIVPEMIRRIEARP
SLSYYATTKDGDLMTNVCSEGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
GHCFDEGSPSRALIDKIMDEWYLVNLVDNDFRSNSAIFEVLNNLRVKDLDVPYAS
>A0A1Q3ZFP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriia bacterium 40-80|TrEMBL
MKVIDHLREAKDTLFSFEILPPLKGKSIQSIYQGIDPLMDFKPKFINVTYHREEYVYKER
ENGLLQKMSVRKRPGTVGICAAIMNKYHVDAVPHLICGGFNREETENALIDLQFLGIDNV
LALRGDSIKTESTFSPQPGGHEHAVDLVKQIEEMNQGNLMVEETTMDPTDFCIGVAGYPE
KHFEAMNFSTDLHYLKQKVDAGASYIVTQMFFDNKKYFDFVDACRAAGITVPIIPGLKPV
KVLNHISFLPKFFHIDFPEELSKELLKCRSNEDVTNVGIEWGINQSKELKKAGVPCIHYY
TMSNSSSVKAIASEIF
>A0A536XXI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MRGVLHSRLRRDPRMDLATKEHSSSSAISELQKHLRDGSFVITAELSPPVSTDPAEFIDH
ALALRGLVTAINVTDGAGSRAHMSSLAAAHFLVRSGVEPVLQITCRDRNRIALQAELLGA
AALGIRNILALRGDDPTLGDQPDTKPVFDLDTTALLATAQRMRSEHRLPSGTEIKGAVRF
VLGAAELPVDPADGWRPNGLLSKMEAGAEFIQTQFCMDPDAVRRYAARLLELGVAQKLPI
LIGIAPIPSARSARWMKEKLFGAMIPDRIVDRLERAADPKAEGRRICVELLQQLAETPGV
AGAHVMAPAFHSAIGPVIEASRVAGTKRAGARRG
>A0A349YE38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MSAPRVSFEFFPPKSHEAEVSLWKTLERLAPLKPTFVSVTYGADGSTRERTHRVIQRISV
ETDLNPVPHLTCVGATREEVDSLADDYWSAGIRKLVALRGDPQGGAEVTYVPHRDGYAYG
SDLVKGLMEKHPFELIVGAYPETHPEAISEEADLESLRRKVDAGAKCAITQFFFDDSVFL
KFRDRVASAGIEVELIPGILPVTNYKTLVRFAESCGVSLPSSLTNLFCGLDDDVTTRQHI
AAHVAVSQVEALSREGVRDFHFYTLNRAELSFTVCHAIGVRGAT
>A0A537AS95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MIFDDEPVPGYPLPILPGHSSPGRLERVLRAGVFTVTTELDPPDSADPEEVYRRARVFDG
YVDGVNATDGSGANCHMSSLAVCALLTRAGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NILCLSGDGVQSGDHPQAKPVFDLDSLSLLQIARMLRDEKRFESGRKLTFAPRVFLGAAE
NPFAPPFEWRAERLAKKVAAGAQFIQTQYCFDIPMMREFMHRARDLGLLENAFVLAGVGP
LKSAKSAQWMRTHVAGTHIPDSVIARLSGAQDQAQEGRRLCIDLIHELREMPGVSGVHVM
AYRQEESVAEVIERSGVLGGRIPWFPERDQQQQPERIDS
>A0A1R4LLS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio ruber DSM 16370|TrEMBL
MGYSYAGHIDALNQNISELSGDLNVSFEFFPPSSPQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLIAAPHLTCIDATREELSQIADDYWNNGIENIVALRGD
IPAGGGKPEMYASDLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVECYLRFRDRCVSAGIDVEIVPGILPVSNFKQAARFAAQNHVKVPGWMNKQFD
GLDDDPVTRQLVGASQAIDMVRILCREGVKDFHFYTLNRAEMTYALCHTLGIRPQA
>A0A0A6N6K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga sp. Mc24|TrEMBL
MRRSLEMGKCVVLEVLTPRGTNLSKFMEFAEEAWETGIDAFTVTDMPMGRVRMAPWAVSH
LLVESGKEVLMHFTKNTRNMIRIQSDLLGCHALGVKNLLLLSGDNPSHGDYPDTTSVNDI
DILDLIRLTKLMNEGTDLAGNKIYGKTDFFVGGALNPLSDEDMKRAKQKVEAGVDFLVTQ
PLFNSEVAKKIKEELSTKILASIVFFENEKQMSYFSNVPGIEIPDEIVNSAEKGDDYLKE
KSFESVLRFVEETKDVLDGFYIVAIVKDLEKIRKVVEIAKS
>A0A537CWP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTGSADRIFSFEFFPPATPEGVAKLRATREQLERLGPKFFSVTFGAGGSTRDRTLAAVLE
IQGAGQRAAPHISCIGSTRESIRATLAAYREHGIGHLVALRGDLPSGTADVGEFRYANEL
VEFIRAATGDWFHVEVAAYPEYHPQSASPREDLASFKRKIDAGADSAITQY
>A0A1A8XL00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Propionivibrio aalborgensis|TrEMBL
MKHTELSIEFFPPQTPEGVDKLRIVRGKLAVLKPEFFSVTFGAGGSTRDRTFSVIKEIAV
EGFEAAPHLSCIGSTRENIRDILHAYKSAKIRRIVALRGDLPSGMAEAGEFRYANELVEF
IRSEIGEHFHIEVAAYPEWHPQARSPRDDLAAFARKARAGANSAITQYFYNADAYFHFVD
EVRALGVDIPIIPGIMPIANFSKLARFSDACGAELPRWMRRKFEAFGDDAESIRAFGLDV
VTELCERLLTGGAPGLHFYSMNQSVLTLEICRRLELG
>A0A636KBZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Uzaramo|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1E3PBU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wickerhamomyces anomalus (strain ATCC 58044 / CBS 1984 / NCYC 433 / NRRL Y-366-8)|TrEMBL
MPTIRDKIQNLKNGEVFLSLEFFPPKTESGIRNLLARMERMSALNPLFVTITWGAGGSTS
EKTLSLVQTCQKELDFTTCMHLTCTNTDKSIIDNALAKAKQAGIRNILALRGDPPRGEEY
FVPNAADFQYAVDLVKYIKQQYGDYFSVGVAAYPEGHCEGADNSEQDVNKDLPYLKEKVD
AGADFIITQLFYDVEKFLEFESLVRTNISQDIPILPGLMPINTYQLFHRAAKLSHASIPT
QILNRFPENIQNDDDKVKSVGVEILRDMIHEIYSRTNGRIKGFHFYTLNLEKSIAQIVEK
SSLLNRVLEYNKDDEDAVMSDDEEIPVITKKEKSRRSSSINTSNKVLVDKIRKDSQDFED
VNNFKFVSPSKKDIVAISSGEGTLGRDATWDDFPNGRFGDSRSPAYGEIDGYGPSLKIAT
KRAYELWGYPVDVKDISKVFINYLEGTIDALPWSELGLSPETAIIQEELIQLNERGFLSL
ASQPATDGAKSEDKIFGWGPKGGYVYQKAFVELFVSKEDWEQKLKPKVESNSKISYYIGD
SKGFFKSSLPKGSSNAVTWGVFPDREILQTTIIEEESFKAWRDEAFSIWLEWAKLYKKNT
ATSKLIHSIHDTYYLVSFVYHDYRNEAGLWELLLS
>A0A1H0UA54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas ruminantium|TrEMBL
MKRVSVELIPRDEETLRGELQLLKQYEGKIDVINIPDLLRFDTRSWEGSAIAQEYFAMSM
PHIRAMDIDLDKELPMKDYLREKGIKEVLVVQGDPPQRMTHEVYPTESTDVIRKFREEMP
EVKVYAGIDQYRSSMRHEVYRTRRKVQAGAAGFFTQPFFDMRLLEIYMDMLDGLDVYWGV
SPVVTAASQSYWERKNNVIFPKSFNPTLEWSVDFSRQVMEMADKKDANVYLMPIKTNLEE
YLAGVFA
>A0A536U1T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MSSRDPAEIDACAGLLEPETAVYISMPPGQTYHGTVALAKRLRRAGFCPVPHVAARRIAS
RGALDEYLARAAGEAGVDSALVIGGDSDRPSGPFESSLAVLETGLFQRHGIAHIGVAGYP
EGHPKIAEAALESALTAKKVLARGAGLDLQIVTQFCFESGPILAWAAKMQGHGLPVHVGL
PGPASLPRLLRFAALCGIGNSVRALRARPRAITRLLVEAGPEAVVRDIARLRGAAIAGVH
FFCFGGLSRTARWLRALQEGRFELTSDGSFRVGTA
>A0A1E3P3T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wickerhamomyces anomalus (strain ATCC 58044 / CBS 1984 / NCYC 433 / NRRL Y-366-8)|TrEMBL
MRISHKLQRSHAEDDIPTFSFEFFVPKTSQGVQNLYDRMDRMYNLNPQFIDVTWNAGGRL
SNLTTDIVQTAQSVLGLETCMHLTCTNMPIELIDKALRDAYNSGCQNILALRGDPPVEGG
EWTAIEGGFTHAKDLVKYIREKYGDHFDIGVAAYPEGHPEETDIDLLVDYLKEKIDAGAD
FIITQMFYDAENFIEWCKKLRAKDINVPIIPGIMPISTYAAFKRRATWCEINVPQEFEDK
LLEVKDDDQLVRKIGIDLVAEMCSKLLNSGFVKHLHFYTMNLEKSSVMVLEKLGLITSTI
VDDLPFRKSLNPTRTKETVRPIFWKNRKYSYVTRTQGWDEFPNGRWGDSNSAAFGDVELF
TSGLLRQSPKRSIELWGEPKTIQDVANLVVKYLEGQVNSLPWSDTPVTSEINSIKNELIE
INKSGILTVNSQPRVNGATSSDPAFGWGPKNGFVYQKQYLEFLMPKSNLPNLISKIETLN
KPYNSNLNPKDNFNLLTYFAIDSTDDLSTNAKDDSANAVTWGIFPGQEVLQPTIVEKVSF
LAWKDEVYRIAEEWSSIFEEGGESKNIIKSIINDYALVNIVDNDYVGNDKIFGLLKDL
>F8A2R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas gilvus (strain ATCC 13127 / NRRL B-14078)|TrEMBL
MSAPTVEPPVTTPAAQPRGTTGEHVAPAPRPLGSVDRPTISFELFPPRNPQAAPRLWATV
RQLESVHPDFVSVTYGAAGKTRATSRAFVSRLLQETSLSPIAHLTCVGTSRAEITAIVEE
FLDEGVRSFLALRGDPPAGEPDWRPHPEGVETASALVELLREIEARRCVASPSQAVRARV
RPLSVSVAAFPRGNAATGGTRAQDVASLLAKQEAGADFAITQVFYDAEAYLGLVAEARAA
GVVIPIIPGIIPTTDPARLLRVQELTGVPVPRDLLDHLGAADDELERHRRGIRAGVDLIN
GILDGGAPGVHVYTYNTHEAALDLLEGAHLDGATRR
>A0A6P1GBI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium yanoikuyae|TrEMBL
MTQTDRARHDAEGPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFVSVTY
GAGGSTRERTHNTVARIAKETPLAAAAHLTCVAASKAEIDEVADAYWEAGVRHIVALRGD
PPEAGTAFQPHPDGYKGAAELVEGLRKRHDFEISVAAYPETHPDALSAQSDIDNLKRKID
AGATRAITQFFFEADTFFRFRDTVAAAGIDADVIPGIMPVSNFAAVQRMSAMCNTDVPAW
MGRLFDGLDQHPAARQLVSATLAAELCRNLYMGGVRDFHFYTLNRAELSYAICHLLGLRP
QVAVDA
>A0A4R1S3Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK251|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSHGRLERVLRRGEFAVTAELNPPDSADPEDVYERASIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLSTPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLHEQCFILVGV
GPLASARTARWMRSNVPGVHIPDAVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLEGRKPWKREANRDDERIVERLEHLREGREENQQELAEIAS
HHTPTH
>A0A4V6S1I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bondarzewia mesenterica|TrEMBL
MKISKKIEQATKEDKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFLDITWNAGGRTS
DLTSELVKTCQGLIGIETCMHLTCTNMPKKKVDIALREAKQHGCRNVLALRGDPPTGKDE
WEAVEGGFVHAIDLVRHIREHYGDHFDIAVAGFPQIQLLPPEERALELKYLKEKIDAGAS
FIFTQMFYDVDIFIDWVKAVREVGITVPIVPGIMPIQTWNGFQRATSLAKTKIPQSFLDA
LEPYKNDDEKVRKIGTRLVADLCRRILKEPIGIRGLHFYTMNLERGTKMLLEELNFVPRV
ETIKPLPWRQSLTPTRRQETIRPIFWSNRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALALWDRPTTFADVANLFKRFCKNELSALPWSDQAASTETSVIAEPLA
RLNELGFLTINSQPAVNGARSDDKVFGWGPSNGYVYQKAYLEFFYADITYHVINKRGDLK
TNTTYQGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGQQWAKLYEPDSPSRKLI
SDLMGKSLLVNVVHNDFKKPDAIFEPFYKAGAEFAAASDATTQPNGHAN
>A0A149V904|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter cerevisiae|TrEMBL
MSLSRLSVELIPRSEDALAQDVTSVKTLFPAADTLNIPDLMRFPLRSWDAAALTMPQFGT
VVPHVRAIDIAPGAPLPGSTLPGLKEVLVVHGDPPADLAHRTYPNSTESIIRRYRKEAPH
LRIYAAFDPYRRAPWRELEDIARKKDAGAEGFFTQPVFDLKLFDLCREWLQDEEVFWGLS
PVIGPRSRSYWETTNHVVFPRDFEPTLDANIQFAQSVLRQLSQDQGCAYLMPLRVKLDQY
LPPLMDALTA
>A0A2M7L9E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium CG_4_10_14_3_um_filter_54_28|TrEMBL
MKLSEILAKADKPLISCEFFPPKTDKGEENLWLCLKELQAISPAYISVTYGAGGTTQDRT
KGIVTRIKDETGLSPVAHLTCVGASRDELAELLADYRAAGIENILALRGDAPEGVDRFEA
VSGGFSHATDLIAFLREQGDFSIACATYPEGHPESAGGVADDIRYLKLKQDNGADAAVTQ
YFFDNDAFFRFRDACRAAGITLPIIPGIMPIGNYDQIVRFSSMCGATIPAWLHEQMRPIS
DDLEAVKALGIELAVKQCRELLQAGVPGLHFYTLNRSEATIAIRNQLTDLL
>A0A4P7IGC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides seonyuensis|TrEMBL
MDLQRRIIEGRGEFLIFALTPPRQEASPEKALEIAGRTAERLRAVDLDGLILYDIDDESG
RNPEERPFPFLPTMDPADYLSHYFDTGSTPVVVYRAVGKYAESDLEAWLRAQEADRRLSV
FVGAASREESVATSLADAQSLRARTRPDLLLGGVAIPERHARKGDEHLRLLRKQDAGCSF
FVTQVIYDVTAAKNLVSDYRYECLARGLAPATFVFTFSVCGSTKTLEFLRWLGVDVPRWI
ENELRHADDTLDASFEYALAAARELMTYCRRLGVPFGLNVESVSIRRAEIEASVELAARL
REGLHRLE
>A0A2V2RT10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MDLLENLRNHILCGDGAMGTLLIERGVALNRCFEELNLHSPGTVRQIHEDYIRAGAQIIG
TNSFAANSYKLSGFGLESRVHEINCRAAQLAKQSAKGCPVYVAGCVGPIGLSATEATERG
FDREAFFREQIGALVDGGVDLIFFETFQDPEELALALRVKQSLHPCPTICSLACNESGRL
SNGTSLGETFHFLLERGADIIGINCISGPHRALRLLELMPEGAPLAAYPNAGRPRYSEGR
YLYEATPNYFAEQAIAMVAAGAGIIGGCCGTTPDHIAALSKAIEGLAPVRKKRIRIPQDL
PSPKPAPLSEESILDQWSGGKRVILIELDPPKTLCLEKYFVAAGALKEAGGDVITLADNS
LAILRVSNLAVGAMLKERGITPLLHLSCRDRNLIGLQSDLMGMAALGMRHVLPLTGDPAK
AGDHPGASSVYDVNSVQLLEIIQQLNRGFTQSGRDLKRRCDFVAGCTFNPNAKNLDAQIS
RLERKIAAGAQYVMTQPIFSAKLAETIAIRTQHLNIPIFLGVWPLLNGRQARFLHNEVPG
ITIPDSTLARMEGLEGAEGRKVGVSIAREIAQEVLAHFSGIYLITPFLAYETTVELTQWI
RAQYPQTSESMQLSCN
>A0A1V4MZ81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aegiribacteria sp. MLS_C|TrEMBL
MYVRAEDGFLIADGAMGEYLFSLGYPASYLASEAIVRSPEIVASIHREYAGAGASALTTD
TFDANVAKLDARGLAERCEEINFRAVRLAARNTECMIMGSVGPPAGGRSFSMEPCDMELT
SGIFGPQISGLLRGGADLILLETQVDPRQARMLYDLVRSFSREIPVAVSFTYGHDLLTPA
GFSIEDSVEAFLNTDIAMLGANHGTGPLQAMDIHSRLRSCSPFPVILKPNSGTARYSEGR
FIFPGNPDHFCRCMLSCAGDGTAMIGGCCGTTPEFISMLASRMSETPSPARISFIRGEEQ
DEPFEKPVLCEPPGLAAGMAAGDALVMELLPPRGGDLSAFASRAEKLRSFSPLTVSIPDS
PMGKVRMSPAISGLYLREKLGMEPLVHFALRDRSLTRVQADLLAMSGFGLGSVFLISGDP
PTLGDYPESTAVYDLSTDQTLELLRNLSLGVDLNGRKLGSGAGFFPGTAVSLGDPGAREK
MERRWEAGCRFFISQPVYSARTLEESADLLEEFPVIPALMPFRNRYSAEYLAAEVPGISI
PEEVLAEIRDMDDEDVLSCSLDMLAELMGSMRGTAAGVYLAGPARGTSRLAEVWRVGR
>A0A561D663|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neobacillus bataviensis|TrEMBL
MNFLDKLKNQILIADGAMGTLLYSFGVDTCSEELNLSQAEQIQNIHRAYIDAGADVIQTH
TYAANYLKLQRYGLEDSVKEINSAAVRNAKKAAQSNAYVLGTIGGNRGIKTSSITIEELK
RSFREQLYCHLLEGVDGLLFETFYDLEELETVLTIARKETNLPIIAQVSLQDPGFLQDRT
PVNEALKRLEGLGADVVGLNCRLGPHHMLLALEQVEIPKHAFLSAYPNASLPTYTDGKFH
YEGDADYFQKSAQRFRDEGVRLLGGCCGTTPDHIRAYASELKNSIPVTEKVVKLKQKPII
VESPPKREYTPLQEIVKERPSVIVELDPPRKLDTTKFFEGAKALKEAGIDSITLADNSLA
TVRISNESLGYLLKSELGMRPLIHLACRDRNIIGLQSHLMGLHTLGMNDILAITGDPARV
GDFPGASSVYDVSSFELIQMIKQMNEGLSYSGKDLGQKTAFSVAGAFNPNVRSVEKAVKR
LEKKIQFGADYFISQPVFSEEKLIEVYENTKHLDTPIYIGLMPLTGSKNAEFLHNEVPGI
KIADSIRERMALLNDNPLQAAREGVAITKSLIDTALDLFNGIYLITPFLRYELTAELAAY
ANQRASEIRGASYAENTIF
>A0A561EBM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rudaeicoccus suwonensis|TrEMBL
MSTPSRGPRRTIPELLADDGPSFSFEFMPPRSEKGEDLLWDSIRRLERLSPTFVSVTYGA
GGSTRDRTIRITGRIEQETTLTTMAHLTCVGSSVAQLRQIVGEYAAVGIRNVLALRGDPP
GGPGGVWTAHPEGLDHADKLVHLVQSLGDFTVGVAAFPDRHPESVDLEMDADVLVRKADA
GAEFAITQMVTDVDAYLRLRDLVDRRGCAMPIIPGLLPVTAAGQLQRLTELNGQPVAADV
VRRIDAVGDDAAAVREVGIAICTEHASRLLREGAPGLHFITMNKSTATIEVFDNLHVPAV
>A0A3E1DWI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MINPTPHASFREQLNSGRFIYGAELVTTRGIPEPDQKPKLVELGEGLAADARIGWVSITD
NPGGNPMIPADWLANLLKPRGKELVIHLTCKDLNRNGLESAAWRYAADGFNNILALTGDY
PTSGFKGPALPVFDLDSVSLVAMLKTMNEGMEVTRPSGKTERLAKTNFFIGAAVAPFKRQ
ERELMPQYFKLARKLQCGAEWVIPQLGYDMRKFHEIKLFLDWANLSAPIIGNVYVLNKTV
ARMFNQNKIPGCVVSDALYAQVEKYAAGPDKGKAFFTELAAKQLAVFKGMGFAAGYLGGV
HKADTFAQIIDLAENYGANDWKEFAREIQFPKPDEFYLFEKDAATGLGDGAQVNAAYLQS
LKEP
>A0A238XV04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibacter agarilyticus|TrEMBL
MKVTDHIKQANGKTLFSFEIVPPQKGQNIQDLYNNVDPLMEFKPPFIDVTTSREEYVYIK
KENGLLEQKMTRMRPGTVGICAALKYKYDVDAIPHVLCGGFTKEETEYVLVDCHYLGLDN
IMALRGDAMKHESFFIPTEGGNRYASDLVAQIRELNEGKYLHNIIETNNKPDFCIGVAGY
PEKHLEAPSMETDLRRLKEKVDAGADYVVTQMFFDNAKYFEFVEKAKSIGITVPIIPGIK
PVAVKRHQQILPQIFRLDMPEDLISAIESCKDNKQVREVGIEWAIQQSKELIANGAPVVH
FYSMGKSDNIKKIAKEVF
>A0A425BT28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scytalidium sp. 3C|TrEMBL
MHHDGSNEPGAALDGARLEKMYDIIKKYEYNFSRHLQILLDALNHYAATETVVLLDLCAR
LSTANQGTEYSGLKNDDDGAVPAGPSMMSFRERDIRIFLLYREPWVVLCTKMHIKDMVAE
AERSGKPTFSFEFFPPKTAQGVQNLYDRMDRMQGLGPSFIDITWGAGGRIAQLTCEMVHV
AQSQYGLETCMHLTCTDMGTEKVDEALRNAYKAGCTNILALRGDPPRDKEKWEATEGGFQ
YARDLVRHIRELYGNHFDIGVAGYPEGCDDQSDPELLLDHLKQKVDAGASFIVTQMFYDV
DNFISWVGKVRAKGIDVPIIPGIMPISTYASFLRRANHMNCAIPPKWTAALGAVKNDDAA
VRNIGKGLVAEMCRKILASGIHHLHFYTMNLAQATRMVLEELNLTPSIERPLKQALPWRQ
SLGLGRRDEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDTYGIRLRGTS
EQNRERWGEPKSVKDVAEIFVKYLESQLDSLPWSDAPITSEADVIKSDLININRRGLLTI
NSQPAVDGVKSSHPVHGWGPNNGYVYQKAYIELLVPPGLIPELTKRIEDNPDLTYYAVTK
TGHLRTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFSLGLDWAKCYPASSP
SRQLIENMMETWYLVNIVHNDFHQGHGLFSLFEGLVVEDFDQPFDAVHHSNGVAIVDGDD
SVATTPKVIEKSLN
>A0A1J1ETR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus thermophilus|TrEMBL
MKIRDLLKARRGPLFSFEFFPPKDPEGEEALFRTLEELKAFRPAFVSITYGAMGSTRERS
VVWAQRIRSLGLNPLAHLTVAGQSQKEVAEVLHRFVESGVENLLALRGDPPRGERVFRPH
PEGFRYAAELVALIRERYGDRVSVGGAAYPEGHPESGSLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIGIPILPGIMPVTSYRQLRRFTEVCGASIPGPLLAKLERHQ
DDPEAVLEIGVEHAVRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGLRPASG
>A0A2V6B9R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIIDIMRGNSPTFSFEFFPPKTPEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIEAILLRYAKSAIGNILALGGDSPAGIAYDKSR
DSFQHAIDLVKFIRRFNESGAHPDHRGFGIGVAGFPEGHPATPNRLVEMDHFKAKVDAGA
EYIVTQLFFDNRDFLDFRERCALNEIQIPIIAGIMPITSISGFKRIAELAGGARFPAKLL
RALQRWQNDPETVKRVGVQYALEQCRDLLDNDVAGIHFYTLNRSDATRVIFDSLAFPRHR
NAQASSA
>A0A2V5YXL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRGDSPTFSFEFFPPKTAQAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
GLVERIQHTTKLDPIPHLTCVCHNEEEIEAILLRYAQSAIGNVLALGGDRPVGIAYDKAR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLLEMDHFKAKVDAGA
NYIVTQLFFDNRDFLDFRERCALVDINIPIIAGIMPITTLNGFKRIAELAGGARFPARLL
RALQRCQNDPEMVRRVGLHFAIEQCHDLLDNDVAGIHFYTLNRSDATRMIFDSLGIPRRR
NAEPSSV
>A0A368BJE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MQNTPHISDLLSQGNPSISFEFFPPKSAEASDRLFSTIHELKQLNPSFVSVTYGAGGSTR
ELTHKLVLRIMEETTIPAIPHLTCVNHSRAEISEILSGYANAEIPAILALRGDPPEENPD
YNRAQDAFCYAADLVSFIQNFNRETSNPRKRFGVGVAAFPEGHPDTQNRLKEMDYLRQKV
DSGADYICTQLFFNNYSFLDFRDRCRLAGIHIPIIAGIMPITTKSGMVRMADLAAGVHFP
AQLQRMLFSAQDDPVAFEKAGTDYATSQCRELLAEGVDGLHFYTLNRSSATAQIATALDL
GQK
>A0A7W9J9Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella italica|TrEMBL
MELICEVEPPTRPDLKKVRHQIGVMSPIADGFLIPDNHIGRATVSSVAVANEVQAMGARG
IACLNSRDRNLLGLRRDLLTAAAYGVEQFLFVHGDDPNEGGRTSQLTVRTMLEETRATSF
PGLGPFQVGATARLGKVPTWKKEADFLYVQVSFDLDELLRWRESVDLTIPVYAGVMVLAS
AKMAQNLAGLPQLAIPDALVEAVERDRDAGVEAACEQVLKIRDSGAFEGVHLVPVSRYRQ
VAARLEREL
>A0A6P4HZC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila kikkawai|TrEMBL
MAGAVVIRRFASLGAFRSLQTFQMLPKDGQQGQGQNRNSCTYNPTLTFAPGQNGGGEQRI
GPLVAEQQKKGRLFYGIEVLARTRKEPVNLDFNTFLPVLPIFVSVVWHSLRYWDVEPISE
VDCIVLCKLLAKRLPTMPHLTCYRMSKQRMDQFLDLEFKNLLALRGDDAEPKQEFTFSAD
LTQFAKCRFGDRISVSVAGFPDGYTRSERTPEHMERNLKIMKAKVEAGADCIITQMCYKP
DAIIKYVKDCRAAGITVPILLGIMAPDTYACYKNMIKKGEAELPPDLAEEVERLQCEILT
DPSQNSDQISQFFVNYNVRLICEVLAACDDVWGIVFFTLNRFGSVHLTLKELQKIGLFNE
VS
>A0A2M4BU42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles marajoara|TrEMBL
EEPAVSSLREKLTQIFRPTSGEGEPSAVRSVFYSIEIAAKDDFNIDQLRRLTPPPVFCAM
PWISDENLRYEADFAQMPSLRLAEQLRREQITVVNHLSCYNLTEVQVDKLLSTQPSIRNL
FIVRGDTVSPDQQFQHSAQLLQHLRQYESTRTTTAATPKLTIGVGGYPGGHAESPSQEDE
LRHLADKVALGADFLLTQTLYDAASFFRYRDRCRAVGITIPIIPGIYLPHSYRQLQTMLN
ITRVAMKPTVRALFEEHRNDTPEAFEAFVVQYFVELVRELLQSNAIEPGSSSDPVGLVHF
FTFNKFSLLEKVISQLKFGQQ
>A0A7L0BM40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spizaetus tyrannus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQESGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRYLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VEQAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>F3P6C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. oral taxon 170 str. F0386|TrEMBL
MERESAGRLSRRFSLSGTPVGSEYGHGLIRSTIQSGRETWFDDAAATRCAGASARIDGDD
VLDNEPTELTAGVGGGGDHSGSGEHGARRSLPTVSLELFPPRPGRAASATWGRIDRLLAT
GPDFVSVTYRPTFVSEPVPRAGAKEHGADPSERVGGRDDGASRVRAVQEETNPSEGVLSH
VLESSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRADDVAGELHH
ADDLVRVIREVEADFFGDGRRHVTIAVAAYPATSDHIEAIEVLAAKQAAGADLAITQVFY
DPADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVKVPDALRSSLGSASGAT
LVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDA
VDRGYLQATPGRGPSFLRCGAPGSAASSCRPVQPHTTITKENV
>A0A1I0QF81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cognatiyoonia koreensis|TrEMBL
MPKISFEFFPPKSLAASFKLWDCVNTLAPLDPAFVSVTYGAGGTTRKLTHEAVETLHAET
GLRVAAHLTCVDATRTETLEIADAYAKSGVRDIVALRGDAPQATDRFTPHPEGFQSSVDL
ISALADTGHFNLTVGAYPEKHPEAADHAADIAYLKRKFDAGATSAITQFFFEADTFFRFR
DACVKAGIDAPIIPGILPIENWNGVQKFAQSCGTAIPQVIRDGFANATRDGNTDLLSTAL
ATELCDDLIRGGVEHLHFYTLNKPELTRDVCHALGITPKARLQKVA
>A0A1V6RHJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium vulpinum|TrEMBL
MRDGHSAAVDITVPDTTGSTFSRILSSSSNPSHCRLIHSKEAMEKKITEKIAALPPDANY
FSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGSTAARSLELAEVCQRQLQL
TTVLHLTCTNMSRKLVDMALDEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNKDFTFAV
DLVRYIRETHGDYFCIGVAAYPEGHPADTFQDVQDPVRDMPYLVEKTLAGADFIMTQLTY
DIEGYQKFEKMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVTIPPPIAKRMEEL
KHDDDAVKRAGVDIVSEIVGGMRDIPSPGPRGFHFYTLNLEKTVSFILEQCDLIPSFSDA
GDAIEDDSTSIPLDFPGRVLRRRRASSINSQPHNRVIVDKLSVHGSSQDSIHEAQAASAG
MPAPPPNRSTTLLISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTANTA
RRLWGHPVDSKDMSTLFRRHVSGELHMVPWSEGGAEEDGQGLNAETELIRPELLKLIDGR
GWWTLASQPAVNGVRNDHPIFGWGPQREGFVFQKPFVEFFCSNNDYTNILKPIFAKHGHD
KLTWFATNVKGDFESSLPTQPADMELDDLGDNPDSVNAVTWGVFRGKEIVTPTIIEEVSF
RAWGEEAFRIWDEWRRIYPRGSPTETYLDTTKNDAWLVCVVGQQFGAGTKRGSKEEEDEV
KWMWRVLAGEEV
>A0A5M8ZII2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter sp. DmW_136|TrEMBL
MSLSRLSVELIPRSAEALAADVATVKTTFPAADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQSGLEEILIVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMQGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLEANILFAQTVLKELAQEKGKAYLMPVRIKLEQY
LPALLDAVA
>A0A3C1BTD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deferribacteraceae bacterium|TrEMBL
AIISEMEGKGEDDMFSLGVDYAVKQCECLWKSGVRGLHFYTLNRSGATEEVL
>F5VT37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis SK255|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVVPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQILDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A452RY17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ursus americanus|TrEMBL
MVNEPRGDGGPPPRSEGSSSGSESSKESSRCSTPGLDPERHDRLREKMRRRMDSGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSREQITGYLQKARRLGLKNILALRGGYPKGHPDAGSFEADLKYLKEKV
SAGADFIITQLFFEADTFFQFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQ
QIKDVIEPIKDNDAAIRNYGIEQAVSLCQQLLTSGLVPGLHFYTLNREMATTEVLKRLGM
WIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFG
ELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFAHYLSGEPNQQGYKVTCLPWNDE
PLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTS
RETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPV
SFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLENCLWQVVED
TFELLNQPAPEGETEAL
>A0A7U5GWF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. P37|TrEMBL
MSLLEKLQTNVLTADGAMGTILYSYGIDYCYEELNIEKPEIIEKIHQDYIEAGADIIQTN
TYSANAIKLARYGLENRVTDYNKAAIQIAKRAAAPGGQFVLGTIGGLRGIRKSDATLDEI
KKVVLEQADALLTGDPDGLLLETYYDFEELSSVVTTLREITDVPLIAQVSMHDPGVLQNG
LSLNDALHQLDSLGAEIVGVNCRLGPYHTIQAFENVTLPEKAFLSAYPNASLLDVEDGRI
VYESEAEYFGRAAVLLRDQGVRLIGGCCGTTPKHIKAAKTRLEGLSPVTKKVVQPSKPIV
IQEAGPVKHQPLHEKAKTERTVIVELDTPRHLETEDYIKGANLLYDAGVDAITMADNSLA
SPRISNMAMGSIIKMQHNVRPLVHLTCRDHNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELLQLIKKLNEGISFSGKPLRKKANFSISAAFNPNVRVVERAVQR
LEKKIEAGADYFITQPVYTKEKIIEVYEATKHLDTPIFIGIMPLTNIRNAEFLHHEVPGI
KLSDEVLERMRECGDDRKKATETGIEIAKELIDTAAKYFNGLYLITPFLRYDMTLELYEY
IKEIDEQKERELTHAETSY
>A0A7K2L227|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID6041|TrEMBL
MSPVPGGPTFSFEFFPPKTDRGERALWETIRRVEALAPDFVSVTYGAGGSSRDRTIGVTK
RIAAETTLRPVAHLTAVGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRGPWTPHPHG
FTYAHELVELVRSLGDFRIGVAAFPEGHPRSAGPAEDLAHFVAKCRAGADYAITQMFFDP
EDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAARDDPAA
AYRVGVDHATRMGLRLLDEGAPGLHHITLNKSTAALEIHRTILSARSVVHV
>A0A2E7QIE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MLALRTWSVRHARLVETVYSAFSQVIKLFTPIFRRIPQPILESPVKVVERWAKGLMFDCQ
MCGQCVLSETGMSCPMNCPKSLRNGPCGGVFADGGCEVKPEIRCVWINAWDGADQMQNGD
TIKDIRRPLRQRMAGKSTWVPIMRGEGGRPPWLEGDDHDFSVATPELSRLQELLQAGEFA
VTCEYNPPNTVITQDIVSKAASLVEACDAVNVTDCAGAYVHISSLATCAILTREGAEPVM
QMTCRDRNLLAVQADIMGAAALGIKNILCMTGDGVEGGDHPDGKPVFDLDSSSLIRTVKH
MRDEKSFVTGKDLISAPELFIGGTANPMAPLTEIEINRMIKKAAAGAQFFQTQFCFDMER
FEHFMNAYRETGLHQTHHLIIGIGPLNSARAARWMRDNIPGVRVPRAIIDRMESVTDQKA
EGREICIEAIKQLKQIDGVSGVHIMAIAQESAIPEIVKRAKIGPQFRS
>A0A3D4MD27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSLPFIPPASCDLRVSFEFFPPKTEEMEKTLWASLDVLAPLQPSFVSVTYGAGGSTRART
HDIVTRIQAQTGIGAAAHLTCVGATRDEIDAIARTYLEAGIRHIVALRGDLPGGQQKYVP
HPDGYAYAADLVEGLRKIADFDISVAGYPETHPEAQNAEADLENLLRKVDAGASRVMTQF
FMEPEDFLRYRDRVAAMGVSVPVVPGILPITNVDRTVSFAKACGAKIPAWMPTLFEGLDD
QPKTRQLVAATVAAEQCRVLYEHGVRDFHFYTLNRADLTLAICHMLGLRAAPAQDVKARA
GGGL
>A0A2E6QEU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MNSGGFATRGAPGGASVRPAGGTRQKSVSFEFFPPKTEKMEAALWESVERLEPLSPTFVS
VTYGAGGSTRERTLATVKKIAAETTMPVAAHLTCVAATKDEVDSAARSFLDAGINHIVAL
RGDPPEGDSKYTPHPGGYDCAASLVEGLRRIGDFEISVAAYPEVHPDAASAEADLDNLKR
KVDAGATRAITQFFFSNDTFLRFLDRARAAGIDIPIIPGIMPVTNFKNVRRFAGMCGAVV
PQWLADRFEGLDDDPETRSLIAATTAVEQCLDLHEAGVDGFHFYTLNRANLSYAICHMLG
VRPQDEAIDAGLQLSMAS
>A0A7J7LLF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingdonia uniflora|TrEMBL
MKVIDKIKEVSIEDKVVFSFEFFPPKIEDGVDTMLDKMDQMVSHSPSFCDITWSVGGSTA
DLTLDIANKMQNMIYVETMMHLTCTNMPVEKIDHALDTIKSYGIQNVLAFRGDPPHGYEK
FVKTEGGFACALDLVKHMREKYGDYFGIMIAGYPG
>A0A0C4UT23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria rulei|TrEMBL
AYGIHLGTEMCKKILAHGIKTVHLYTLNLEKSALAILANLGLIDMT
>A0A1Q3PLX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter sp. 50-39|TrEMBL
MTKVTEYIRRAEGKPLFSIEIIPPLKGQNINELLNSIESLMEFNPPFVDVTYHREELIDR
VGPDGTIERIPIRKRPGTVGICARLMERFKVDAVPHVICGGFTKDETEDVLIDLHYLGID
NVLVLRGDAERSAGVFRPKPGGHSYASELVTQVDNMNKGILLNAETESAPTDFCIGVAGY
PEKHFDAESFDTDYAALKKKIELGGNYIVTQMFFDNRKYFTFVERCRAEGITVPIIPGLK
PLSTKKQLTVLADIFHLEFPQELVNEVAQCATDKEVRQVGIEWGIRQCKELMAYGVPVLH
FYTMGKSDNVAQIARGVF
>B6B3G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium HTCC2083|TrEMBL
MNAPQVSFEFFPPQSLEASFRLWDTVQVLSPLDPTFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNATREETLGIAKEFAKAGVREILALRGDAPKGQDRFTPVEGGFANSV
ELIEALSATGDFKIRVGAYPDRHPEAESTQADIDWLKAKLDAGASEAITQFFFEADTFFR
FRDACVKAGITAPILPGILPIENWKGTRNFAKRCGTEIPQWLNDAFKTAERDGRSDLLAT
AICTELCSDLMGGGVDALHFYTLNRPELTRDVCHALGVTPKMDLQNVA
>A0A378H009|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria rosea|TrEMBL
MPIDPPHAGPAAALLRDFSLEMTGKDVPALEEAAAVVPAGTRINVTFLGNEDLGMRVAAA
RAVREHGFVPVPHLSARRLRSQGELEEFLAALAEVGAAEHVFVVGGDPETPEGPYPDSLS
VIRTGVLPRHGVRGVGVSGYPEGHPGIDDAALWSALTDKTAAIREQGLEPEIITQFGFDK
DPVLEWLAEVRRRGVDTPVRIGVPGPAGVRRLLGYARRFGVGTSAGIVQKYGFSLTNLLG
TAGPDRFLRDLAAGLDPAVHGQVLLHFYTFGGLRATAEWVREFGTDGGIP
>A0A2D6FVP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MNDVDSPAVDSKLVRRLISGEFAITAEVTPPVAAAAAPLLEKAAVLKDCVDAVNVTDGAS
ARVHMSSTASAAILAGAGIEPVVQFTCRDRNRIAIMSDLLGVAAQGVHNLLMLTGDDPTA
GDQPDAKPVFDFASQDLIRIARQMTDKGALPSKGVKVSGDDIEPDTRPIDTPPQFFVGAA
DTPTAEANEGWINGLRNKIKAGAQFIQTQLCYDMDIVRRYAELLEEKGFSEHLFFLLGNG
PLLSAKSAIWMRDNLWGVVMPDSVLQRLEDADDAKAEGIKLCVEQIEEMSRISGISGVHL
MAPINTSSIPGVIAAAGLENRT
>A0A2D7H5X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MTDISFEFFPPKSPEAEEKLWTAVGRLEPLAPDFVSVTYGAGGSTRDRTHACVRRLVDET
QLKPAAHLTCVAASRADIDSVIEAYATAGVGHIVALRGDMPDMGEFQPHEDGYSGSVELV
EAIAARGGFDITVSAYPEKHPESSSLQTDIDLLKAKADAGATRAITQFVFDTPAHLRFRD
AVAAAGITIPLIPGIMPTTNFAGARRMAAACGTHVPDWMSAMYAGLEEDPDTRKHIAASI
ATDQCRTLLDEGFEHLHFYTLNQADLTFAVCRILGLCDSQQESKPL
>A0A0Q8SRT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. Root217|TrEMBL
MNAAKAQATGFPVSLEFFPTKTQAGADKLRAERQQLYALSPEFCSVTYGAGGSTQEGTFG
AVREILAEGVPAASHFSCIGATRESVRQELAQLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLKAYLAKVQAGADAAITQYFYNAD
AYFRFVDDVQRLGASIPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDKLRSEGVPALHFYTMNQSAATLEICRRLVL
>S2QX25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei subsp. paracasei Lpp126|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTRKQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFHERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A1R0F9K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bartonella apis|TrEMBL
MSAPSLSRRPDLGDKLKVSFEFFPPKTEKMEEMLWQTVKRLAPLKPEFVSVTYGAGGSTR
ERTGRTVERIIKETHLNAAAHLTCVDATREEVDGVARQFASMGIHHFVALRGDPSNGAGG
RYHPTPGGYANAVELVAGLKAINPDFEITVSAYPEKHPESPDFATDIDLLKRKIDNGATK
AITQCFFDNHFYEDYIERVRKAGIYIPILPGILPIHNFWQVKNFCSRNGTHIPDWLAQRF
EGLENDQKTHDLVAAAVAAEQVLDLVEHGVEDFHFYTLNRADLVYAICYLIGIRPQSALK
ANNAK
>A0A389MQR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp|TrEMBL
MSRPETLRQVPPEEPRMNPSRHRASRDGYRPIRVSIEFFPPKTDEMERILWSSIERLAPL
QPKFVSVTYGAGGSTRERTHNTVARMVRETALKPAAHLTCVDATREEIDAVVQSYWDAGV
RHIVALRGDPAEGVGHAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEAASLDA
DIDALKAKVDAGADQAITQFFFENEVYLRYRDRVRAAGIDIPIIPGILPVQNFKQAANFA
RRTGASVPYWLAARFEGLEDDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVY
AICHLLGLRSQGAKGAAKAA
>A0A426QER9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Guyparkeria sp. SCN-R1|TrEMBL
MPIPVSCEFFPPKSAEGEAKLREVYQELARAIAPEYFSVTFGAGGSTQTRTFETVREIQR
DSGIPAAPHLSCIGSSRDGIAAILDDYREQDIRRIVALRGDLPSGMQDPGDFRYANELVA
FIREHSGDWFHVEVAAYPEIHPQAPNAEADLANFKRKVEAGADAAITQYFYSIEAYRRFL
DDCERLNIDVPIVPGVMPITNYQQLARFSDMCGADIPRWLRKRLEGFGDDLEGLRAFGHD
VVTDLCRQLVDAGAPGIHFYAMNRSQPVIRLCRDAGLVGD
>A0A543P2Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria rosea|TrEMBL
MPIDPPHAGPAAALLQDFSLEMTGKDVPALEEAAAVVPAGTRINVTFLGNEDLGMRVDAA
RAVREHGFVPVPHLSARRLHSQGELEEFLAALAEVGAAEHVFVVGGDPETPEGPYPDSLS
VIRTGVLPRHGVRGVGVSGYPEGHPGIDDAALWSALTDKTAAIREQGLEPEIITQFGFDK
DPVLEWLAEVRRRGVDTPVRIGVPGPAGVRRLLGYARRFGVGTSAGIVQKYGFSLTNLLG
TAGPDRFLRDLAAGLDPAVHGQVLLHFYTFGGLRATAEWVREFGTDGGTP
>A0A2E9UYE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSLTIDALXXAAANWSIEVTPNGASKVESFADALEPETHVNVTFLPGSDPADTYLVAKRL
HDEGMIPIPHIAARSIKDRKHLEKIVSTFAKQASVKEVLVIGGGVDKPIGEFDCSMQILK
TGILQANGITKIGVAGHPEGSPDIADNEIKRALQEKNEFAIKENLNMYIETQFCFEAKIV
LAWEKKAREDGNQLPIRIGIPGPATIKTLFRFAQISGIGPSMRFIAKQAGNVAKLMTVQS
PHLLLAGLAEGMAADKACLIKHFHYYPFGGFVRTAKYARAISXGNVXLKTNGGFEXIEN
>A0A246BPS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus indicus|TrEMBL
MTRVSIELVPRSRSGLRGEIAQVVAALPGVDTVNIPDLTRYSLRSWLGCAFARPAYRAVP
HLRAVDFNPREPLPFLGTLEQHGITEVLVVTGDAPADMSARVYDQDAVDLIRRLRREAPH
LTVYAGLDPYRQSFARERDYLERKLDVGATGFFTQPFFDLRVMDAYSDLIPDGTQVWWGA
TSILTESSLNYWRARNHAVFPRSFTPTLECNRAFAADLLAFARERDQHAYFMPVKVDVQA
YLEGIL
>A0A7X7RX25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MKKDELTRFFNDQLVIFDGAMGTELYRRHIFTNRSYDEVCVSDPALVESIHEAYLTAGAD
VLTTNTYGANEQSLSQHGLSPRMDEINAAGVRVACRARDSRDWGRQILIAGSVGPLRTKG
TSSEERVEILRRQAESLLRAGVDFLMFETLPSREAALEARKAMSAFPEDTAFVLSHSMPD
GASPEEDIVHRAVFAEDGLPQAFAVGFNCGLGPSAMLKIVEQAVKICDVPVIVQPNAGSP
TSVDNRQLYLCDPEYMSTYAVRYAALGVRAIGGCCGTSPDHIRDLANTVKPLGRKRIEIK
VAEEKEGVSLVPERPLAERSRLGAKLASGEWITTIEIQPPRSWNLESIIEKAKVCKEAGI
DVINVPDGPRASPRLSPLVTCLKIQENAGIETVLHVCSRDMNFIGLQAQLLGCAAAGVNN
ILFITGDPPKLGNYSFASGVFDTDSIGLVTLQKHLNQGIDLGGQKIDPPTAAVMGVGADP
NALDFDREIRRLREKVEAGANFVTTQPVFDVAALERFLDAISDLKVSVIAGIWPLASLRN
ALFMKNEVPGVVVPDWIIDRMKSFDTREEQLAIGIEIARDTLSKIRSRVSGVQVSAPLGN
VKTALAVLA
>A0A419T8Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermohalobacter berrensis|TrEMBL
MSLLREVLENGEFAITAEMAPPKGTDISHLRKCAQLMKGRVHGVNVTDFQSAVMRVTSLA
TCKILKEEGLEPVLQLTGRDRNRIATQGELLSAGVFGIENVLCLTGDHTVVGDHPQAKPV
YDLDCIGILQAATTLMDGKDMAGNELNKAPEFYLGACVTPEYEPLEIQIIKMKKKIKAGA
RFFQTQGVFDIETMRKFRELTKDLDCKILAGIIPLKSAGMAKFMNKNVPGINVPDKLIER
MKNAEDKKKEGIKIAAELIQQLKEENLCDGVHIMAIGAEENVPVILDEANLTPSYAANA
>A0A8C1BE67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MMCNTSDSSGVSNSGESSKESSRCSTPVQDADRTDRLRDKMKRRIESGDHWFSLEFFPPR
TASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHL
TCCNQTKEKITAHLNKAKRLGLKNIMALRGGMNGDFDGDFFCVNLVTFRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKE
ALLQMWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVN
CRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPR
VNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQW
AKLYEDESPSRMIIQYIHDNYFLINLVDNDFPLDSCLWQVIEDMFTLLDSPPETQEEGSQ
S
>A0A7X6V0B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MTTPTIRELLAERRQPTLSLEFYPPRTPAGFDLLRRSIERMRPVQPEFVTCTYGAGGTTR
EFSFAAWELLAEMGFTPVVAHLTCVGASRDDLAAQIHRIHASGIRNIMALRGDPPRGETT
FTPAPDGLAYAADLVALIKSLHPDICCGVAGYPETHPEAASPADDLRHLKAKLDAGADFV
NTQLFFDNAVFYRFVEDARAAGITAPILPGLMPVASPAQLERAIGYSRATVPPALREAVG
HPDPDTARDAGLQWMAAQICDLIANDVPGIHLYILNSDRTVLDPRLAACLAQWRGAPLST
NHTERPDP
>A0A8H8QUQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnellula hyalina|TrEMBL
MHVSQMLSEAERSKQPKFSFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVNEALKETYKAGCTNILALRGDPPRENEK
WEATEGGFQYAKDLVKHIRDTYGNHFDIGVAGYPEGCDDQDDLELLVDHLKEKVDAGATF
IVTQMFYDVDNFLDWVRKVRAKGITIPIVPGIMPINTYASFLRRCNHMNCSIPPKWMEAL
EKVKNDDAAVRNIGTGLVAEMCRKILDSGLIHHLHFYTMNLAQATKMVLEDLKLTPSDER
PLKQALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQEWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEQNRKRWGEPISIKDVAEIFVKYLENGVDSLPWSEAPITSEADSIKADLI
GLNKRGFLTVNSQPAVDGVKSSDPVYGWGPANGYVYQKAYLELLVSPQLMDELIQRIERD
PDLTYYAVNKAGELKTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMD
WAHCYSNLSPSRNLIQNMMENWFLVNIVHNDFHQTHGLFRLFDELSVPSIDKPFEVEYKN
GIDTNGVNGSQPDVLENNSVMNGA
>A0A2V2GUJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MRKNCSDPYGKMLIFQVQRDILCPYIYILKKQGRARTGTIMNLLQQKLAESLTIFDGAIG
TEIYRRNFFVNASFEQLNLTAPDVILDIHHQYLKAGAEVLTTNTYNANSRRLAKFGLSEQ
TEAINRAGVKLAREAAAGKALVAASVGPVGEPDSDQDRRPRSELLAEQIRTLSDADFIIF
ESLRRAADLKAVLEAVAEFPELVYVPSFAIEPHPHINDSATIAEFMEQLNASRPCPAPTA
IGLNCGGGPESTLGVLEELTALTQLPVIVQPNAGQPKGVDGRMIYMTSAEYFSTYAKRYA
MLGAAAIGGCCGITPDHIEELARTIKPLMQAEKRALPALEVKECDLKPEVPLAERSRIGC
KLADGAFIKLVEITPPRGFDLTGTIAGAAKCKAAGIDAVNLPDGPRASARISPLVTALEI
QRNAGIETILHCCCRDKSLIGLQADLLGCAGVGINNILFITGDPPKLGDYPFSSGVFDVD
SVGLVKIQKRMNQGVDLGGKPLNAVTKMVIGVGADPNAIDLEREYRRTCEKVEAGAEFII
TQPVFAPEALFVFLDRIAHLNVPVIAGIWPLTSLRNAEFMRTEVPGVVVPDAVMERMAAD
ESKEAQREAGIAIARESVAAIRSRVRGIQVSAPFGNVDTALRVLA
>A0A8C1UMS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MQDYSWIHTCESSKSDSSGVSNSGESSKESSRCSTPVQDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCECDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGAHFIVTQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNCRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQEEGSPS
>A0A8C1LLY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGKDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIITQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTES
>A0A7X7FDU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
QHVDFRQLYLCSPEYLTTYALRYIALGARAVGGCCGTTPEHIADLARSVKPLGKSQQIAQ
VIAKAAPTETPQAEEVPLAERSRFGRKLAAGEWVTTVEISPPRGWQTADIVAKAKLCQEA
GVDVINIPDGPRAAPRMSPIVTALHIQQQAGIEAVLHVCGRDRNFIGLQADLLGCSGCGI
HNFLFITGDPPKLGNYGFASGVFDTDSIGLAKLQKDLNRGFDFGGQKIDPPTAAVIGVGA
DPNAIDFQREIDRLRQKAAAGADFVTTQPVFDPDALKRFVEAIADLHLPVIAGIWPLASL
RNALFMKNEVPGVVVPDAIITRMEAANTREEQLATGIAIAREAVAAVRPYVAGVQVSAPL
GNVRAALAVLAP
>A0A7C5JN71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MLAQMRDEGRFACGEEIRDGKNSPVVSPRIFIGAAENPFGDPLEFRAVRLGKKVSAGADF
IQTQCIYDMDRFRRWMEMVRERGLHEKVKILAGITPLKSLRMAKYMRDSVPGLIVPEYYI
NRLAKLKDPKEQAEEGIKICVEQIQQLREIEGVAGVHIMAIEWEHKVAEIVEKAGLLPRP
SVANETEQKGRS
>A0A8C1H9F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
RYSSVLGLHSPVITPGGLGRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDR
LRDKMKRRIESGDRWFSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSD
KETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGGMNTLA
ADRQNLTGLLQLMAKGMSEPIKDNDAAIRNYGIQQAVEMCKVLLASGEVPGLHFYTLNRE
VATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPN
GRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITSQTNRN
GHKVMCLPWNDDPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSSDPIVGWGPAGGY
VFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVQGRNTTNAHDMQPNAVTWGIFPG
REIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDF
PLDSCLWQVIEDMFTLLDSPPETQED
>A0A2W6VTM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arsenicicoccus sp|TrEMBL
MALEGLLRGARLEILPTGSIAEQVHAHVEPGRTVTVTASPAKGLEATLALTEELADRYHV
VPHLAARMVERAELPDIVARLRAAGVTEIFVPGGDATPTETAFTNALDLLIELEELGRPF
ERVGITGYPESHPGIDDDVIVQSMWDKRRYATDIVSNMTFDDEQVGRWLERIRRRGIEQP
VWIGVPGPVDPAKLLKMATVIGVGDSMRFLRKQHGVFTRIALPGFTTTRFAHRVAALAGT
ERLGIGGLHLYSFNQVEKTEAWRREQLSRAADLRRP
>A0A1Z9ETH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium TMED123|TrEMBL
MKVTEHIIQTKKTLFSFEILPPLKGKSIQSIYDSLDPLMEFKPPFVDVTYHREEYVYKKR
KDYLLERYAVRKRPGTVGICAAIMNKYQVDTVPHIICGGFNKEETENALIDLDFLGVDNV
LVLRGDPIKSETYFTPEEGGHSYASELLHQVDNMNKGIYLDEDLKNSSPTNFCVGVAGYP
EKHFEAPNIRSDLHFLKKKVEAGADYIVTQMFFDNQQYFDFVALCRDNDINVPIIPGLKP
LATQKQLTLLPQRFHLNVPNPLVDEVLKCKSNDEVRQVGVEWGKQQVKELIEFGAPCIHF
YTMGKSDNVQQIVGSFV
>A0A603BIY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 50:b:z6|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A561UT56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces brevispora|TrEMBL
MLATGETLYSFEFWAPKTEKGERNLWNALRRVEAVGPSFVSVTYGAGGSTRAGTVKATQD
IAAESTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGPWIEHPQGV
RYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVDKCRAGADYAITQMFFDPE
DYLRMRDRAVAAGCETPIIPEVMPLTSVRQLERFPQLSNAALPPALKERILAAKDDPAAV
RSIGIDFATQFCAKLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A1K1QYM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sancti|TrEMBL
MKGTLQHKITAGKSGIVFYSLTPPKVTTESEKVAIIAGSQIERLEHLDIDGLILYDIQDE
VLRTEKERPFSFIPTISPEVYSKDLLTSLQVPKIIYKSIANHTKEMFTDWLSKNCDLEAT
VFVGASSQQQVQATNFSLSDAYQVKKELGVDLLLGGVTIPERHTRKGDEHLRMFSKMQNG
CNFFVSQCIYNINETKNVMSDYHYHALSNDTQPVPVIFTLTPCGSLKTLQFMEWLGIEVP
KWVYNDLKYSKDILQSSINTATNIAGEILNYATAKNLPVGFNIESVSNKKDEILAAHEIL
ENVLHLVKPLKNQVVNEKRAISAY
>A0A2W6V3A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arsenicicoccus sp|TrEMBL
MSTPRTRISVELVPRSEESVRAEMQQVSEHLTGVDTINIPDLVKFELRSWAATQVAREST
ARGDGTAYRTIPHIRAADVDPDAPLPMAAEARRTGELLVVSGDDADYFHSATYPVDAVDV
IRRIRAELPEVRIYAGLDPYRQSMTTEMRYLDRKLAAGASGIFTQPFFDTHLMAAWASVL
PRDIPVWWGATSVTTDGAMGYWRRRNRVVFPGGFDTSMTWQRDFARRVVDFARERGHHAY
LMPVRAPLLDYLGGVLDGS
>A0A1S7QLX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. NCPPB 925|TrEMBL
MLRSETARHNGDIRGDIRLSFEFFPPKNAEMEAQLWETVAELKKWDPDFVSVTYGAGGST
KAPTLDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVIEEFRNAGVRHFVALRGDPSTGIG
TAYQPHPEGYENAAALVKGLREIGDFEISVSAYPEKHPESASEAVDIDMLKRKADNGATR
ALTQFFFDNDVFERYMERVTVAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERF
EGYDEDLEGRARVAAEVAAEQIADLQRRGFNEFHLYTMNRAPLVDAVLENLGLERLRRSA
A
>A0A4Y8AT56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gramella jeungdoensis|TrEMBL
MKVTDHIKQANGKTLFSFEIVPPQKGQNIHDLYNNVDPLMEFKPPFIDVTTSREEFVYIK
KENGLLEQKMTRMRPGTVGICAALKYKYDVDAIPHVLCGGFTKEETEYVLVDCHYLGLDN
IMALRGDAMKHEQYFIPTVGGNNYAAELVKQIHELNQGKYLHEIIETPHKSDFCIGVAGY
PEKHLEAPSMETDLRRLKEKVDAGADYVVTQMFFDNQKYFNFVEKARSIGITVPIIPGIK
PIAIKRHQQVLPQIFRLDLPEELILEIEACKDNKQVRQLGIEWAIQQSKDLIANGAPVVH
FYSMGKSDNIKAIAKEVF
>A0A434ZRY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.011.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETAIPAAAHLTCVGATRDEVNAVIHDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFRQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A1T4JHV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema porcinum|TrEMBL
MNSNHTIFSFEVFPPKKTMNIETVYKTLDELSGIKPDFISVTYGAGGSANCGNTLNIANR
IKDVCGVQSVVHLPCINMTKKDALFVLEQFQEAGIENILALRGDRVEGVEQCNDFAHASD
LIRFIKEFDAKRTNGKSFKLFGACYPERHPESPDVLSDIKALKDKVDAGAEHLLSQLFFD
NEKFYRFVERARLAGITVPIEAGIMPATNKKSIERMVSMTNAVLPKKFVRMMERYADSPE
AIRDAGIAYAVDQIVDLVTNGIEGIHLYTMNNSYVAERINSAVRSLFSEPPVEMEIK
>A0A369C8L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioalbus denitrificans|TrEMBL
MTTSPLTPYPSPTFSFEFFPPKTDEGREKLRGVRERLARLDPAYFSVTFGAGGSTQAGTL
EAVLEIQAAGNDAAPHLSCIGTDRGFVRELLTTYRSHGIRRIVALRGDLPSGSRGAGEFR
YANELVAFIREETGDWFHIEVAAYPEFHPQAASARADLENFARKVKAGADAAITQYFYNP
DAYFRFLEDVRALGVEAPVVPGIMPITNYSQLARFSDACGAEIPRWIRKRLESFGDDRDA
IVAFGEEVVTRLCEKLLAGGAPGLHFYTMNRAEPTLALWRNLGLPGSE
>E5Y3H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bilophila wadsworthia (strain 3_1_6)|TrEMBL
MNIGQLIAERGKPFYSFEFFPPKDPDQWPDFFKMAERLAPLEPLFTSVTYGAGGSSQDAT
LEIVSHLKKEFQFETMAHLTCVGATQDYITQYLQRLRDNGVDNVLALRGDIPKGQDIDWE
TAEFRHAADLVRFAKAHYPDMGIGVAGYPAPHPESPSFASDWRYTVAKIREGADFVITQL
FFDVREYLHFVDRLSDMGVSVPVIPGILPIQSLESIRRTLSLCGANIPGKLYLALEEANA
KGGAEAVREAGLKFAVQQIRTLLDNGAPGIHLYTLNKASMCLRIAEEVGAL
>A0A3R9DTV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. FDAARGOS_558|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKTLEELWSSLWQVT
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLAIEA
>A0A7V8IYW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSIADRFQPGRPVLSFEVFPPKRDGDVESLYRAFGELAPLRPDYISVTYGAGGTNVGLHY
EINARLVKMGITPLAHFTCVGQGKDAIRAQLDKLWEAGVRNILALRGDPPKGTGKFVPHP
QGFAHAGELVAFIKANYKFCVGAACYPETHPEAKSPADDLAFLAAKVKAGADFLVTQMFF
GNDAYFSFVKRCRDAGIATPVQPGVMPVQSPKFFERDWGVGVPPELRKAVESAADHDEAA
SRGLEFAKSQCRDLLGRGAPGLHLYIMNKVRPARGILEAIGRKS
>A0A7C5KE32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MKICRILEQGRPVFSFEFFPPKSARAEARLMETLWDLSRLGPDFVSVTYGAGGSTRESTL
QLVSRIKSDLSLEAMAHLTCVGSSREELEAIVGKLRAAGIENILALRGDPPAGEETFRPP
PGGFAHASELAAFLEAKGGFCLGGACYPEGHPESPDLDEDIRHLKTKVEAGVEFLVTQLF
FDNAHYFSLLEKARAAGIEAPILPGIMPVTSYNQVKRFTEMCGASIPEELEERLQAAGED
PLKVPTVGVEWATAQCRELLEKGAPGIHFFTLNHSPATRAVFEALRRA
>A0A838RZ80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrinomonadaceae bacterium|TrEMBL
VTSVEVLPPKGVDAQKTRDSIRLLKDAGVDGVNIPDGARAQSRMSAMATAVLVEQQIGIE
SVLHYCCRDRNLLGMMSDLLGASALGLRNLLLITGDPPKMGPYPDATAVFDIDAIGLTNM
VNKLNHGLDIGNNPIGQPTAFCIGVGVNPGAINPEEEIRRFEYKVEAGAQYAITQPVFDT
DQLRDFIKSVEHVRIPIIAGIWPLVSYRNAEFLHNEVPGVRVTPSIMERMRAASAISKEA
GRDEGLKIARESLLEVRDLIQGVQVSAPFGNVKYALEVFGALEEFSRKEAEVATNRSAEE
>A0A7V3TYT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MTGGATAEPSGLSFRRLLESGGFPIGVEIVSTRGFPANPGDAPPIILARELLSHPRIGWI
SITDNPGGNPMLPADWIAQFLFNERDRIVIHMTCKDTNRAGLESLAWRLAAEGLHNVLAL
TGDYPTAGFGGKPQGVFDLDSVGLIALLKAMNEGLSVTTRPGKRETLPPTRFYIGCAVSP
FKRYERELVPQYFKLVRKIATGAEWVITQLGYDMRKYHEVKLFLQARGISGIPVIGNVYL
LTKTVAKLFHDRQLPGCVVTDELWELCQKYAAGSDRGKKFFAELAAKQLAVLRGLGFAAG
YLGGIHKLESLEEVLRHLDSFAPDDWRQFLKEIQFSFPDEFFFFEHEPETGLSGPEKINR
QYLESLRKPRRSRYVTLGYRLSRLVHRLAFTRGKGLWNLAQRLYQRWAGKPRPPAPARVL
YGLEKFSKYVMYGCQDCGDCSLPDCAYICPKRWCSKCSRNGPCGGSVDGECELRNKECLW
AIVYERLKAYGESEEMLSGPPVLYNAELAHTSSWANTYLNRDHHGVTEKRDLGQDTSGGA
NTHGE
>A0A7H4M2S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella michiganensis|TrEMBL
MYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRAITQFFFDVE
SYLRFRDRCVSAGIDVEIIPGILPVSNFRQAKKFADMTNVRIPTWMAKMFEGLDNDAETR
QLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A832IGH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudothermotoga hypogea|TrEMBL
MKLIDKLKEGPILSIEVLPPSRGHGVEEIFRTVDQLMEFPISFINVTRHAPELAYVESDG
QIVKITKVKRPGTVGLAAALMHRYRIDVVPHVICYGMDKYQIEDLLIDLHLIGIRNVFVV
RGEYENPLSEQQDRSSYRHAVELVQHIANLNRGIYLYPTEGSEPTDFCIGVAGYPEKHFE
APNMEEDLMNLKRKIDAGAHYVVTQMVFDVEIYKRFVQMARNFGIHVPIIPGVKPVVNLK
SIYSIPKKFFVTIPARFVSQMHQASSSEEEFKIGVRFTAKLAEDLLAVGAPGIHVFTMGR
AKATKAMLQLLYSKQV
>A0A7V7XE99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MAKQPFLERLKQKPLLGDGAMGTMLHQSGVKLGHSFDSINVTDPSLVASIHRQYLEAGAE
LIETNTFSANDFKLSKLGLQNQTIEINEAGVELAKRVIEDLGCKDRVYLSGSVGPLGSWI
APIGRITEEKAYAAFYKQIATLIFAGVEVIQLETFSDVNEIAIAARAARDVKSDIPIIAT
LTFNRDDRTLLGDTAVMVAEELRKTGADVIGVNCSVGPAQLLRLTSIIRSIAPDKHLLVS
PNAGWPEQIGGRVVYPATPEYFGEYALAFAEAGATVIGGCCGTTPAHIKSMREALDDEAR
PTSTLVVVPKQEGLVIEPPIEQPTQLVQKLRAGEFITTVEVAPPRGSTAERIVAVVEMLR
DAGVNFIDVSDSPLARMRMSPWAVAYLIQQQVGIETVLHFPVRGRNLLRVQGDLLAAHAM
NIRNIFVTMGDPTKIGDYPQAFDTHDVVPTSLIRMIHEQFNSGLDYAGNGLGRSTNFTVA
AALNLAPTDLEKELALTRKKVESGTDLFLTQPVFEPPKIEEFLRAYENRYGEPLGTPLVV
GLLPLYTARHAEFLHNEVPGMIIPDALRQRMHSATNMEAEGIKIAQELLVEIKQIAQGAY
LMPPFGRYYLAAEVIDVLAVPA
>A0A7C5R2X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MKSGSNLERILTAGYFAATGELGPPKSADAEVIRRKAKILKGYVDAVNITDNQTAVVRMS
SIASGAILLQEGLEPIIQMTCRDRNRIAIQSDLLGAYALGMRNLLCLSGDHQTFGNHPGA
KNVYDIDSIQLLQIVRGMRDEKKFQCGEAIEVEPRFFLGAAANPFADPFDYRPLRLAKKA
KAGADFIQTQLIYNVDKFREYMKRVCDLGVHEKVHILAGVGPVKSPAMARYMQTKVAGMD
VPDWVVQRMEKAPKEERKKEGIRICAEIIQQVREIPGVAGVHIMSVEWEEAIPEILELAG
LLPRPVAGN
>A0A7V9G7C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
GWPGSPRGSRLTAQLRHLQDASGTPGMLEILAGDTTLAQAQETALTAHLLGLRLVLIDSG
VFAGVTRSDLATASADPLALVRALKRLNEGRDLGGSRLDEATAFTIGVRVRAEDAGRLDE
FAAAGADFLTLQPIYEPARFRAAMAAAAVTVPLFAEVMLLPDAATAEELDNELPSLSVPE
RLKQRLRTDSGEDVRGVLRFLAAWRTKLAGVCIMSPDERTEPAERVIREIRKG
>A0A7V4M5D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRLLTPHHLEGTRPAAFGIMATVVSSSLREILTGSRFAYGAEIVTTRGYSTPGAATQLVE
MGSALLQDPRIGWVSITDNPGGAPMLPPDWLARQIGADPKRIVIHLTCKDRNRNGIEAAA
WGYAAEGFENILAVTGDYPTTGFGGVADPVFDLDSVGLISLLKSMNEGLRVPGRKGAIET
LPKTHFYIGCAVSPFKQHERELVPQYFKLLRKIRVGAEWVIPQLGYDMRKFHEIKLFLAA
RGYEHVPVIGNVYMLNRAVAELFHSGKLAGCVVSDGLLEQCNRYAKGPDKGKTFFRELAA
KQLAVFKGLGFAAGYLGGINKAETFFEVIDLAEKYAPDDWRQFIKEIQYSNPGEFFFFEH
DPETGLSAPDRINPEYLRSLKSPPKSKHVTLGYRISRRVHDLAFHRGKGMYNLLTKIFAR
WDKKPGWMSRFSYWLEREAKHLGYGCQDCGDCSLPDCAYLCPMASCSKHSRNGPCGGSAG
GLCELLDKDCFWARVYERLKYYRESEQMFDGPVVIYDAKLKHTSAWANTYLDRDHFGREH
QKQQAAAATADKPNAATATADPPPEPKPDR
>A0A7W1NDK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRIDRLFAAKPRTLSFEFFPPKTDRGWYTLEDTIESLAPLGPDFVSVTYGAGGSTRARTR
EVVEHIQAKSGLTAMAHLTCVNATKSDLRALLDEYAGAGIENLLALRGDPPKGATRFTPT
DGGCAYARDLIDLIRADGRFAIACAAFPEGHPEAASREADWQRLVEKYAAGADVAITQCF
FEPAPYLAQREWLLRRTGTSPRLIPGILPIVDFHALERFCLRCGASVPASVRARLAPLAD
DPIAVRKAGIACTIEFCAALLDAGAPGLHIYALNRSTAAAEVVSALRVMGKLE
>A0A7Y2GVD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrinomonadaceae bacterium|TrEMBL
MRDFREIIENDSVYVFDGAVGTRFYDKGVYINKSYDEINLTAPDLVREVHEEYVNAGADV
IQTNTFGATRHKLKQYGLEGQLHEINVSAAKIARQAAGDDLFVAGSIGPLDLRIEPYGPT
SYEEAREMFAEQVAALLEGGVDLFVLETFADLSEIQQAIRAIKNLSSLPIVAQIQIQTDG
KTVFGATPEIFTARLDEWGADVIGLNCGVGPTHVLNELENMRRLTDKKLIAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRFIKAGAKFVGGCCGTTPKHIKLIADSVRAISPRTTQVSVK
APAKAAENKKTVEVEPVSPLDRSKWSRKVAQGEFVTSVEVLPPKGVQAARTLKSIGLLKE
AGVDAVNIPDGPRAQTRMSAQATAILVEQQVGIEAVLHYCCRDRNLLGMMSDLLGAAALG
LHNLLIITGDPPKMGPYPDATAVFDIDAIGLTNMVSKLNHGLDLGNNPIGEPTAFSIGVG
VNPGAMNLDEEIRRFEWKVEAGAEYAITQPVFDTGQLREFIERIEHVKIPIIAGIWPLVS
FRNADFLHNEVPGVRVTQNILDRMRVASEKSKEHAREEGLQIAQESLEEISDVIAGVQVS
APFGKVKYALRVFEILPQFSKTKDKTVASES
>A0A2U2SA73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTDFLSLLQSSTPLLADGAMGTLLHARGVEHTHCFDELNLTDPAKVAEIHRQYIAAGAQI
ILTNTFGANRYKLHKHGLEGKLTEINRTGVEIARRAVAESGKAVWVAGDVGPLGVRIAPY
GRVQPLEAREAFLEQVRALAAAGVDLLVIETMTDLYETVEAIAAAKTFENLPVVATMTFT
RDDRTLLGDDPAKVASTLTQAGADVIGVNCSGGPAQLLRILRQMRRAAPEARFWVKPNAG
WPEHVGGRVMYAAAPEYFRDYALEFWKAGASVIGGCCGTTPEHIAAMRKSLDATPAMTLE
PVSITTAPLTETEPAESPSELAQKLAAGKFIFAVEMDPPRGLATQKLVAAASLLKESGAD
VIDVADSPMARMRMSAWAVCDVIQRQVGMETTLHFPTRGRNLLRVQGDLLAAHALGIRNV
FVVMGDPTSIGDYPEAADNYDLVPSGLVKLIKQGFNLGLDHSGTSIGQPTSFFVGSALNL
CPPDPESEIKNLKRKLKAGADFFLTQPIYDSEKAKAFLERFAEANGAPLDKPVLVGILPL
VSVRHANFLQNEVPGIVIPDETMQRIQQAGETASREGVQIAIELIEQIKSWGQGVYLMPQ
FHRYDLVAEIIEATKG
>A0A367ZGN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MNSSPTLKDLLLNAGVPLLSDGAMGTQLHARGITFDECFDGLNLTNPDLVFQIHCDYLKA
GSDLLQTNTFGANRYKLALHGLEKDLRRINRQGVQIARQAAGSSSRKVFILGDIGPLGVR
LAPYGRVRPEQARQAFREQIEALLEAGVDGILLETFSDLLEIREAIEAAKALSDLPLIAS
MTFTRDDVTLLGDTPAQVARQLYEYGADLIGVNCSGGPAQVWRILRQMGQTLLASKKTLP
PFSAMPNAGWPEQVGGRIMYPANAAYFGEYALAFCEAGARLVGGCCGTTPEHIAAMRAAL
DGQTGGCAPSVSELTLPIEIEDARGEVEAPSRLAKKLAEGRFVISVEMDPPRGLSTHKLL
AGASLLSEAGADVINIADSPMARMRMSPWAVCELLQRTFDIETTLHFPTRGRNLLRVQGD
LLAAHALGIRNVFVVMGDPTAIGDYPDAMDNYDLVPSGLIKLIKQNLNVGLDQAGAELGQ
PTHFFVGCALNLTPTDFGQEAKNLRRKLEAGADFILTQPVFQPRRAEAFLQFYQEKYGEL
KTPLLAGVLPLYSIRHALFLHNEVPGIQIEEETLERIRKAGEDAPEEGIRVALELIEQMR
GWISGIYLMPAFHRYDIASEIIEACRKS
>A0A350WUP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPGFTPGRRYQPPFMPFKRQPFKKRLLARIELAVKSPLFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGSTPERCYVDESRPCIWYKIYERSFKLGREAQLLEVLPPMDWEKAGTDAW
SDVFIQAKKIGVGTIVSGLTSGKAGSVSQTLDSIFRPVRQPDWWQGDAEYHAPKYTEPVS
ELERRLKAGEFVVTAEVAPPLSVNTDKLVRHINVLKKYATALNFTDNASATPRMSSVACS
KIALEHGAEPVMQINARDKTRVGLQSEVMGASALGIRNLLCLTGDSMAMSPGPKGRMDIV
DIDSIQMLWILRRMRDEGKYLDGREIKTPPQYFLGSAASPFASNMKFQALREQKKVNAGA
QFFQTNVVFNADDLDKWLNELAKRDVLGKVHILIGISPLKSFKMARYMNNKIPGVFIPET
VMKRMEHAETQGNAEEEGVQIALELIEKIRTKQGVSGVHIMAVGWEEIVPRIVEEAGIGS
LIVG
>A0A7Y4SRU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MKIAELFGRGRPVFSFEFFPPKTDEAGNSMLATVKDLADMLAPDFVSVTYGAGGSTRGRT
VELVSRMQSELGLTTMAHLTCVGHTQDELAQLLGRLASRGIKNVLALRGDAPGGKFEPTP
GGFAHASELAAFLRERYRFCIGGACYPEKHPESPSSDDDLRWTAHKVAAGAEFLITQLFF
DSEDYFRFVERARAAGITVPIVPGIMPITSVSQIKRFTQMCGARIPDELRARLERFEDDP
SVVMAIGIEHAIRQCRRLLEANAPGLHFYTLNKSHATRSILAAVKAL
>A0A3M2AU57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSLHPGAETAVTSRHELPSLRERLRHSLLVLDGAMGTSLNERGLAFQDCFEAACLDRPDD
VRAIHAAFLAAGAQGLQTNTFGANRYKLDKHHRERDLERILEAAAALAREAAAGRAHVLG
AIGPLGPQIEPLGRIGRLEARLAFREVAAVLAPLIDGFSLETFSCVEEAVECVRGIREVS
DLPVIAHVTVVNSGRTLLGSTVEQAAEALAEAGADAIGLNCSTGPRAVLEGIQRMAAVCD
LPLSARPNAGMPREVDGRVFFESSPDYFGRFARRFFQAGGRIVGGCCGTTPEHIRALAGA
ARAFRAGGRIEPPPVHARPRAEVVAERPLQPLPLAERSRLGRALAGDEGPISVELLPPAT
PDTSRLVEAACALREGGATCVNLPDGPRASARLSNTAAAVIIQRDAGIEALVHFCCRDRN
LLGMQSDLMGAEALGLRNLLVITGDPPYRGNYPEATAVFDVDAIGLCNIVDHLNHGLDLG
GNAMRARTNFCFGAALNHTAGDLERELARARWKILAGVDFLITQPVFDLGALEHALSRLP
ADHPPVLAGIWPLRSLRNAEFLASEVPGVVVPPAVLERMRAADEAGRAEAEGLAIAVETL
ERAAPLVAGFQLAAPFNRVEPALELLAAAHALA
>A0A7W1NWM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTKLSFRERLQQATPILSDGAMGTLLHQHGAPITTCFDELNLTHPEQVERIHRDYLEAGA
ELIETNTFGANRYKLAKHGLVAKVAEINRAGVELAKRMITASGKDAYLAGSVGPLGSRLK
PFGRVKVEEARAAFGEQIKALAEAGVEVIQMETFSDQNELLEALAAAREVAPDLPVICHM
TFSQDDRTLLGDLPAQVARQLYEAGADVIGVNCGGGPQQLSRILQAMHQAVPEAILSAMP
NAGFPESVGERMMYPATEEYFADYALTFKAIGAKLIGGCCGTTPAHIAAMRAALDNPDLP
VRHIHVSEVTLDDLMAVPERPTELAQKLAAGKFVITVEMAPLRSFVPQKLLAAAQLLKEA
GADMVDVADSPTARMRMSPWALCHFIQTRVHMETVLHFPTRGRNLLRVQGDLLAAHAMGL
RNLFVVMGDPTKIGDYPEAMDSFDVAPSALIGIIKHKMNTGTDQAGNSIGQPTSFTVGCA
LNMFATDLDREIQTLVKKLESGADFALGQAVFEPHRIELFHKRYREITGEDFKLPVLMGL
MPLYSPKHARFLHNEIPGISIPEVLMERMDNAGENSAQEGVKIAQELLHDMRGMVQGAYI
IPAFGRYELVADVIDSVLVSS
>A0A7Z7J3E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. phaseoli|TrEMBL
MSPNHHDKTARPVIPTDTPSGASTITDAYSLEVSVKDIGALTNAAPGILPGCAMFIPYLP
GQTEAARLAAAQMVRRLGFEPVPHLSARRIGSLEELQAFIARLVGEADVTGCLVIAGDPS
TPKGPFADSVSLIETGVFERSGIRTIGVAGHPEGHPIMRTTEQWDVLQRKCRSIQERGMA
PLIVTQFGFDADIVMTWLEALRARGMTHPVRVGVPGPASVGVLARYAASCGVGACASVLS
NYGVSIGKLFGNAGPDRFVDHLVGRLTEAHGDVRLHLYPFGGIAQSVEWVAHYRSCKASQ
DRVSSVAAD
>A0A7T4YF47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MHAKDIFETYKTTFSFEFFPPKTEASAEALFKAVKELEELKPTFVSVTYGAGGSTRELTH
DLVLRIKKETQVTTVPHLTCVCHSEKEIDDILQRYANEGVENILALGGDPPVNLEGYDRS
KDAFQHAADLVRYIRKFNESGQHPNGKGFGIGVAGFPEGHPGTPNRLLEMDYLKAKVDEG
ADYICTQLFFENRDFYDFRERCELAGIEVPIIAGIMPITTQAGMKRMAELSAGSRFPASL
LRAVERADGDKEAVKRVGVHWATEQCRDLLDNHVRGLHFYTLNKSDATKEIYLNLGARDS
AALGGRFK
>A0A2J4P483|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella michiganensis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAKDYWDSGIRHIVALRGD
LPPGSGKPDM
>A0A0D0IZA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio harveyi|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDATRDELIDIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHNFDISVAAFPEVHPEAKSAQSDLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A1Z8SAQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium TMED48|TrEMBL
MKITEHIAQSPGTTQFTFEILPPLKGQSINQLFDVCDELMEFNPPFVDVTYHREEHVYKN
AGNGLLEMKVIKKRPGTVGICAAIQGKYKVDAIPHILCGGFSKEDTENFLIDLDFLEIDN
VVALRGDALKSETYFKPNTDGHQYANELVGQIADLNKGIYLDDELLNSHATDFCIGVSGY
PEKHMEAPSMESDIHFLKKKVAAGAEYVVTQMFFENQKYFDFVEQVRAQGIDVPIIPGLK
PLSTLKQLNMIPHRFHVDLPEAFVKEVINCKDNKAVRQVGIEWCITQSKELKKAKVPFLH
YYSMSKSDNIKAIAREVF
>A0A3A8QT76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus aberystwythensis|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTVEELAPLEPGFVSVTYGAGGSTRDRTV
ELVTHIKQHSGIEAMAHLTCVGHTRDELRDVLRRLDAAGIENVLLLRGDPPQGQTKFEPV
PGGFTYAEELVRFVREEDFNFCIGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRMGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVGALKGRS
>A0A1H9CK76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyunsoonleella jejuensis|TrEMBL
MKVTDHIKNAKGKALFSFEVIPPKKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYIN
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGIEN
VMALRGDSMKDEPYFKPCDGGHAYASGLVEQIAKLNRGKYLHDEVEAEHYSDFCIGVAGY
PEKHMEAPSLATDLKRLKAKVDAGADYVVTQMFFDNQKYFDFVEKAREIGINVPIIPGIK
PIAVKRHLQLLPQVFKIDLPQDLIDAVENCKDNKAVRQVGVEFAIQQSKELLDFGVPVLH
YYSMGKSDNIKVVADALF
>A0A2R5FU57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc commune NIES-4072|TrEMBL
MHHTHSPTAFQRAVQAGEFLITAEVAPPKGGDPAHMIQMAATLKGRVHAVNITDGSRAVL
RMSSLMASVILLQNGIEPICQVACRDRNRISLQADLMGAHALGIRNILALTGDPVKAGDH
PDAKAVFDLEAVRLLQLIRKMNQGVDCNEKPLTDGALDLFVGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFERLEKFMDTIAAGYKKPILAGIFLLKSAKNAQFINRCVPGVN
IPQHIIDRLAKAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDAIAPILDLAGVAPV
NQLVSK
>C5EJM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium 1_7_47FAA|TrEMBL
MKIRDILAQGKPTLSFEVFPPKTEDNYNTVEKAAKEIAKLKPAFMSVTYGAGGGTSDYTV
GIASDIKEYGVTPLAHLTCVSSTREKVQGVLKELKAHGIENVLALRGDIPENGQTPKVYH
YASELIREIKQSGDFCIGAACYPEGHVESANKSVDMDYLKQKVEAGCDFVTTQMFFDNSI
LYSYLYRIREKGITVPVIAGIMPVTNAKQIKRITQMSGTYLPSRFMSIVDRFGDHPAAMK
QAGIAYATDQIIDLIANGVNGIHIYSMNKPDVAGKIKENLSEILGNEYTCTP
>A0A3L7QEL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRIRDLFQSKPFVMSLEVFPPKTEAGDEGLYRALERLRPYDPAFVSCTYGAGGSTQNRTV
DICRRIQTEFALPATSHFTCVGATRLELLDWLSRATQNGIANIMALRGDPPQGQAEFRAV
EGGLANANQLVSLIREHYPNMGIGVAGYPEKHPEAPSLDVDLQNLKRKVDAGADAVFTQL
FYVNENFLRFRDRCGAMGIEIPIVPGIMPITEFARIKRITALCGAVFPSSLAARLEAVQT
DPQAQFEIGVEFAIEQCRELMTAGVPGMHFYVLNKSESCERILEGLGLKPEPVTA
>A0A3L7VBU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRIVDAYQAGRFGLSFELFPPKNAATEATMWQTVKELVFFQPSFVTCTYGAGGSTRATTL
DVIEGVRSRHNLPVASHLTCVGSSVDELRSYLREAEARGVAAIVALRGDPPKGEAEFRPV
DGGLRHASELVSLIRAEFPSFDIIVAGYPETHQEAISPADDLLNLKRKCDAGGEVVVTQL
FYDNADFFRFRDECNRIGIDAPLVPGVMPVTHYAQIRRIASLCKARLPERLTQAFEAAGD
DESAQFEVGVDFATRQVQELLDGGVPGIHFYVLNRSPATVRVLQQVAIAR
>A0A4P5Y3P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSQTVTGIPRRIDQLLAQRAKTLSFEFFPPKGDKAQILFDACVEQVAELGPDFLSMTYGA
GGSTRAGSLAALQKMRALAPRPALLAHLTCVGSTRAEMAGLLDEWSAAGIENVLALRGDP
PRGSGAFAPVPGGYAYADELIAAVRSDGRFAISCAAFPEGHPEAASRESDWQRLAGKFAA
GACLGITQAFLDATDYLAMRRWLDAQGHTGSRIVPSILPVASWPWLLNFKQRFCPNLGLP
ERWRTVLEPLAGDALASRAAGISLTIDLARDLLAAGAPGLHLYTLNKPMAVAEVVTALRR
ERLL
>A0A4Q5S380|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIDHIREAKSTLVSFEILPPLKGKTINSIYDHLDPLMAFKPSFINVTYHRSEHVFKKR
ADGSFEKVEVRKRPGTVGICAAIMNHYKVDAVPHLICGGFTKRETEDALIDLNFIGVDNV
LVLRGDAAKNETVFEPETGGNRNAFELLCQVNNLNNGIYLEEDIRDGFRTKFSIGVAGYP
EKHFEAPNMDTDLAYLKAKVDAGAEYIVTQMFFDNAKYFEFIKRCRAAGIEVPIIPGLKP
LTSKKQLAVLPRTFHVDIPNDLINEIMKCKTDADVELVGGEWLLQQSRELKSSGVPVLHY
YTLGKPKIVCDVVRELF
>A0A349J6Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRLDDLFRRQARTLSFEFFPPKNDRTWYTLEDAIDQLAPLGADFVSVTYGAGGSTRAKTR
EVVEHIHAKTGVSAMAHLTCVNATRGELQTLLDEYAGAGIENLLALRGDPPKGQERFTPT
DGGCAHAVDLIDLIRDRGGFASLCAAFPERHPDAASREADWAHLAQKLRRGASGAITQCF
FDPNAYVEMLAHLTRLTGSHPRIIPGILPITDYHALVRFCERCGASVPQSVHAALAPLAD
DKVAVRKAGMAWTVAFCRELLEAGAPGLHIYALNRSTAAAEIVTALRLSGHLD
>A0A3L7QWB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSIVDVYENGRFGLSFELFPPKNPDSEQLMWRTVEELVAFQPAMVTCTYGAGGSTRDKTL
DVIEGVRKRYHLPVASHLTCVGSSIDELRGYLQAARSRGVSAIVALRGDPPQGATVFTPV
AGGLCYAAELVALIRAEFPEFGILVAGYPETHQEALSPDADLKNLKQKCDAGGEVVVTQL
FYDNADFFRFRERCVAEGIRAPIIPGVMPVVNYAQIRRISTLCKARLPESFTRAFEAAGE
DEASQFEVGVDFATRQVQELLDGGVPGIHFYVLNRSPATVRVLQQVGMGR
>A0A3N2NIC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Isolate-110|TrEMBL
MRVIDHLTRNDGRTAFSFEILPPLKGNNISRVYGIIDRLREFDPKYINITSHRSTVEYQE
RPDGTIVKKKIRKRPGSVAIASAIQNKYGITAVPHIICKGFTRDETEYALIDLNFLGVHD
LLLLQGDAKGPDKSTDPSLVNLHATDLQAQVNDFNRGIYADGEPFEANATPFSYGMACYP
EKHEAAPNMESDLRYARIKVDNGASYLVTQMFFDNQKYYDFVARCRAEGITVPIIPGIKP
VVTCSQLTVLPRVFRSDIPEPFAAELARCTTDEQARAVGVEWCIAQCRDLMAHGVPSLHF
YTLMATDSVARVAKEIY
>A0A842S8Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MGKRPAYSNLCKSIEAENFTFTGELEPKKILNLDEIIESAKEMKRTKKIAAANVTDGPQG
DAYLSSLVPSYKVQEEAEIEAVWQVTIRDRNRVALFGDVLAGAILGLKNILVLTGDHTAL
GDHKKGRAVYDIDSTQFCEMLSQMIDDGLDYEGNEIKGGNIEMNFGCVANPNSNPREPEI
LKVGRKVEQGVDFIQTQTAFDIDEAKDFLKDLEQYNVPVLLGIFPLKSHGIAWYFDNYIP
GVSVPKDLLKSLKKAEKENKGNKPAKYAAIDKINIEFFKPFIEEIRKTTKAAGIHCMAVE
YERLFEPLLQEFPEYM
>A0A3R6I3R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM16-23|TrEMBL
MNLREYLKETNLITDGAFGTYFAAKYQTQEIPELANLSDPEKVKKIHEEYLNAGANFIRT
NTFAANTETLQERFPEVEKNIRAAVEIARSAADGKNVWIAGDIGPIPVNGTEDAAAAADE
YYQIAKTFAETGVKVLDFETFADLDGILPAIKKIRAEYDMFIAVSFSVNQFGYSAAGLSA
KRLLADAAAVPGIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPVYFAEKMKELQELGADILGGCCGTDPEFIREMFAWDGILKKGAPEKEAESSGQSEH
VVRQGFLYDENGNRKEKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMANKVRQATGLNVMPHICCRDRNAIAMRSLFLGAAINDIYNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFANNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTEEDAARLRRIKDETGARILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKASRKEGEAVGIQLAKEVMKLVEDFADGYYFSFPFNRVYMLKDICNCSVGLRTCCAD
RNKTQA
>A0A8F7V524|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus amyloliquefaciens|TrEMBL
MGLLQDLKERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIADLGADITGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTDKEVKIRREEEVI
SVRNERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKQKQKTEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A842QH14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MVLKPLFMKPRTLYSSNPFFSRQPKQISISLVRLPYTCTEEIQILVQTHLSRLLEDNRFV
VTAEVGPPHGADEQLLIDRVLHVKDYCDALNLTDNVRGIPTMSSMVCSHFVRDCGIEPVM
QMSARDRNRILFESELYGAYALGIRNVCFMTGDHSLLGSHPEAKMVYDLDSIQALQLASH
LMSGNDLAGDTLEGTPHFYLGATFNPYADPIELQSWRVNKKHKAGARFFQTQAIYGVSRF
ERFMNRLDVDAIKTLAGIIPLKGPRMARFMNRKIPGIKIPETMIRRLVDAGDGLSGNEKR
GVVRSEGIRIALETIEKVRAIDGVDGIHIMGVGWEESIPTLVKEAGLYPRPKKGE
>A0A7X0D5K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis mwathae|TrEMBL
MLGTVTRSGAAPRPAPRPRHIRDLLNAGEPTFSFEFFPPKTPEGQRKLWRVIREIEALAP
SFVSVTYGAGGGTRDRTVEITERMATDTTLLPVAHMTAVDHSVRELRHLIGRFADAGVSN
MLALRGDPPGDPLGEWVRHPEGLNYADELVRLLKETGDFCVGVAAFPYKHPRSPDIESDV
KYFVRKCRAGADYAITQMFFEADDYLRLRDRVAAKGCEVPIIPEIMPVVKLATIERSEQL
SGAPFPRALAAEFEKVGGDKEAVRRLGIEQAQRLCERLLDEGAPGIHFITFNQSTATREI
YREIAPNRVPAGGAARP
>A0A177C1J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraphaeosphaeria sporulosa|TrEMBL
MHISKMLAQSKEEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPKFIDVTWGAGGSLS
SLTCEMVKVAQSVYGLETCMHLTCTDMERSKIDEALHTAYEAGCTNILALRGDPPRESEK
WQAVQGGFKYAKDLVKYIREKYGDHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGGTF
IVTQMFYDTDIFIDWVHKVRAKGINVPIIPGIMPISTHASFLRRAKWSKIKVPEPWTQAL
DPIKNDDSEVREVGKGLVADMCRKLIDAGILHLHFYTMNLAQSSRMVLEELDLLPDVESP
LQKPLPWRPSLGLKRREENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDARSPAFGEFDA
YGIGLKGSNEQNIKLWGKPTSIRDISEIFVKYMSGNLESLPWSESAISKEADTLQQNLID
LNRRGFFTINSQPPVNGAKSNHPVYGWGPAHGYVYQKAYLEVLVSPEYIAELITRIERDP
EITYYAVNKDGDLKTNSPEGPNAVTWGVFPGKEIVQPTIVEAVSFLAWKDEFYRLGQQWA
NCHASTSPSRYVIEDVMDTWYLINIVHNNFQEENGLFPLFNGLEVTDMEKELHSTGIING
DVTNGESTADASPTNGVKTTLNDLVEAAKSATSTVTNGITA
>A0A1H2HGU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas pohangensis|TrEMBL
MTAQRRYSFEFFPTKTDAGHDKLMGVARELASYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVGVPTAPHLSCVGDSTTDLRSLLQQYQAAGIRRIVALRGDLPSGMGMASGELRYANEL
VEFIRDESGEQFHIEVAAYPEMHPQARNFENDLQNFARKAKAGADSAITQYFFNADSYFY
FMERVHKLGIDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDMQSIQAFG
EQVISQMCERLLEGGAPGLHFYTLNQAEPSLAIWHNLKLPR
>A0A0U3IIJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas rubra|TrEMBL
MALSLQEKILDPNQGVYLIGTTPPKSGTERDKVERIATKLLDRLHEIEYDGVIVYDIQDE
SSRTNVPRPFPFKETVDPCEYSRLVKSLSKLDVITYKSVAQRNSAEFKQWLSTTKQEFGL
NNLVLVGSPSSQGKINLPLPEAYQALAQHEENFFLGGVTIAERHASKRNEHERLIEKTTQ
GCEFFISQAVYDAQATIDLITSYARTCKQQGIAPKRLILTFTPCGGEKTLQFMEWLGISV
PEATKWRMLDADNTLSESIRICRENLDSILRSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKATMELTLAEKQIA
>A0A7V9NWA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKLIQKLSQSKKPLFSIEILPPLKGKSIQSIYDGIDPLMEFKPAFVDVTYHREEYIYKKR
DGGYLEKVSIRKRPGTVGICAAIMNKYNVEAVPHIICGGFTKEETENALIDLQFLGIDNV
LALRGDSIKTEPAFVPEPGGHPYAIDLVKQITEMNRAQYLDEEMKDAAPTNFCIGIAGYP
EKHFEAPNMISDLKYLKAKVDAGAEYVVTQMFFDNSKYFAFVKLCRENGITVPIIPGLKI
LSTKKQITTLPKIFHIDIPQPFYEELEKCKDDKEVKEAGIKWCIQQSKELVKANVPCLHF
YTMGTSEATKRVAKEVF
>A0A8C6NMH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius furzeri|TrEMBL
MVNQVQRVDGSWLSCKSDSSGTSNSGGESSKESSRCSTPVLDAVRSDRLRDKMRRRMESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEEEEGGFNHAV
DLVKHIRSEFDDYFDVCVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTF
LTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKREESVFEVFTCYITGQLNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDAVVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRV
NYHIVNVHGRNLTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLKSCLWQVLDDMFELLDLRSTEKNKTKD
>T1K497|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetranychus urticae|TrEMBL
MTFSKEPPSTSDQPVVSSVKLIDKITNYVNQYGKPFFSLEFFPPRNETELESFWPLLDQL
KQGNPLFMDITWHSRSSLDPNNHCSSLAIAGSTLKQLNHETVLHLTCYDYDITTLESILN
SAKSLGLRNILALRGDVPASNQDENKVFNGLSNSKSDQIIKSNNFLDKLTCALDLVKFIK
TKYGDFFTIGVAGYPMGHPEAKTYSDDLNYLKSKVDAGADFIVTQLSFSADQYISFIKDC
HAIGIKVPIIPGIFPIQTKASIRNISKLTKIDPPNEVKKSIEACKGDIEAIKKYGLQHAV
DLCKKLISSDVNIPGLHFYTLNRDNCVTEILKQLNLWNPRSDYEESIMAGDIQNSPLVLP
EGIQQPVHEQ
>A0A0B6AR24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia megaterium (strain ATCC 14581 / DSM 32 / CCUG 1817 / JCM 2506 / NBRC 15308 / NCIMB 9376 / NCTC 10342 / NRRL B-14308 / VKM B-512 / Ford 19)|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINVAGVKLAKQAAKDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLNEGVDGLLFETYYDFEELKTVLTLARKETDKPIITHVSLHDIGVLQDGR
PLADALKELEALGADVVGLNCRLGPYHMIQSLEEVPLPDRAFLSAYPNASLPAYVEGKLE
YETNEDYFVESARLFREQGVRLIGGCCGTTPAHVRAMSSALKDLPPITSKVVKMRPAVTV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRIRGEVEGLAIAKNLIDTAYELFDGIYLITPFMRYEMTEILTRYI
HDKQLVTSERKI
>A0A256HFV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halorubrum sp. Ib24|TrEMBL
MSAGTQAIKRSDGVGALLTDARFELMPFESFEDEIRHLPDDATIAVTTSPQLGIDTTVER
TEQAAALGYDVSPHIAARYVEDRDHLDEIAERLTDAGVTDIFVPGGDREEPAGEFESAHD
LLVALDELGHSFDEVGITGYPEGHDFLDAEALSDAMAKKSPYATYLVTQLCYDPDAVLEW
IDDIRDDGVDLPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVRQLVGSRG
VYKPDDLIDGLAPYADDDHYKIRGIHIYTFNQTPDTESWRTERLGR
>A0A7W1UPQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTDHIKQAQSTLFSIEILPPLKGKSIQSIFDGIDPLMEFKPSFVDVTYHREEYLYKKR
EGGYLEKVSIRKRPGTVGICAAIMNKYHVDAVPHIICGGFSKEETENALIDLHFLGIDNV
LALRGDSIKSEPEFIPEPGGHSYAIDLVKQVVNMNKGKYMDDDLAEVAPTNFCIGVAGYP
EKHFEAPNMISDMRYLKAKIDAGSEYIVTQMFFDNAQYFEYIKKCKEQDITVPVIPGLKI
ITTKKQATLLPKIFKIDVPQPLLEEIEKCKTDAEVKEVGIEWCINQSKELIKAGVPCLHY
YTMGSSEVTRRVASKVF
>A0A661ZN28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MSLFTPGRRWQPPFFPFKKEPFGKRVLRKTERWIKGPLFGCRMCGNCLLQETAFICPMEC
PKGMRNGPCGGSTAEKCYVDETRPCIWYKIYERAFKMGREEMLLEVLPPLDWDKVGTETW
GDVVRSIKKYGTGKFMKDRFSGNKEKKAHSWEAVFKPVRQPDWWKGDSAYHAPAYEEPFS
ELEKQLSSGKFVITTEVAPPLSTATGKLKRDIDMVKELVAAVNFTDSASASPRMSSMACS
KVAAELGADPVLQIAARDKTRSGLQSDIVGANVMGVHNVLCITGDNARIGPTPTSNTNIL
DFDAIQMLWILRRMRDEGIYLDGRKMKSPPKLFLGSAASPFASEPKFQALREEKKINAGA
QFFQTNLIFDPDGLDLWLEALDKRNILDKVYILAGVTPIRSNRMAQYLHHNIPGVTVPKT
ILDRFEDSSADDYEELGVEIALEIIEKIKSKTGINGMHLMSVGWEAIVPRIISEAGLN
>A0A7W2GNH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNAEMESQLWETVDELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIADGHLPTAAHLTCVDASRDEVHQVVEEFRNAGVRHFVALRGDPSTGIGTAYQ
PHPEGYENAAALVKGLREIADFEISVSAYPEKHPESASEAIDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGIAIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A8I1P5X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MTPPRPSQPDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYE
RAKVFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPVYQISCRDRNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRVMRDNAKFLSGRKLTSPPQ
VFLGAAINPFAPPYEFRPLRLAKKVAAGAQFVQSQYCFDVPMMRQYMQRVRDLGLHEKCY
VLCGVGPLASAKTARWIRSNVPGIHIPDAVITRLEGAADQKAEGKRLCIDIINEVKEIEG
ISGIHVMAYRQEEFVAEIVDESGVLKGRRPWHREARADDRMVADRLGQILREGGPDEQPQ
QMVKDAAH
>A0A519IR04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp|TrEMBL
MKITDHIKNANGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QDNGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDL
>A0A8F8CJ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lelliottia amnigena|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVNAGIDLEIIPGILPVSNFRQAKKFADMTNVRIPLWMQKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2G2Y5H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum annuum|TrEMBL
MKVIEKIQEAIKNDKVIFSFEFFPPKTEDGVENLFERMERMVTHGPSFCDITWGAGGSTA
DLTLEIVKRMQNMVCVESMMHLTCTNMPVEKIDQALDTIKSDGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGIATKEIYENDLAYLK
KKVDAGADLIITQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTK
IPEEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILANGIKQLHLYTLNMEKSALAILMNL
GLIEETKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDEYPHGRWSNAQNP
SYGALTDYQFMRARSRDKKLQEEWAVALNSVEDIYERFKDYCLGKLRSCPWSELEGLQPE
TKIINEKLGHVNTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSQEKLN
ALVEKCKSFPYLTYMAVNKEGNWISNVNQTDVNAVTWGVFPAKEIIQPTVVDPASFMVWK
DEAFEIWSRGWAQLYPEADPSRKVLQQVQNSYFLVSLVDNDYINGDLFSIFKDI
>A0A7V1WZF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKITEHIQNANGKTLFSFELIPPLKGHSIQGIYDAIDPLMEFKPPFIDVTSLREDFIYKE
QENGLLQKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLHFLGIEN
VLVLRGDARRGDASFVPTPNGHCYATDLLQQVVNMNNGVYLHEHYDNMMRTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGAKFIVTQMFFDNQRYFDFVNGCRAAGINVPIIPGLK
PITSSKQLISLAKTFHIDIPEDLSDAIHEAKSEKDVKDVGIEWMINQCKELVKFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A2A2GKA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus salipaludis|TrEMBL
MTTPSVSFEFFPPRNLDQSFKLWETANALTPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
NYGLNVAAHLTCVDASRAETMRIVEDYAKAGVREIVALRGDPPQGAARFAPHPEGFADSV
ELIEAIAEHGGFTIRCGAYPEPHPESPGTAADVAWLKRKVEAGASSGITQFFFDADVYFR
FRDACAAAGVSAPIIPGILPIQSWAGARKFAARCGASVPAWADEAFAKAGPEGERALAVD
MAVDLCRRLIEGGVDRLHFYTVNRPQMTLAVCEGLGIAPRQAKVA
>A0A2N7IQQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 10N.261.52.A1|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPPGGGVPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A1I6EJI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. kpr-6|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDKTGLEAVPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A522G0W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MIFYESLNSGKFVVTAEVGPPKGTDIKETLHHMELLKGKVDAANVTDNQSAVMRICSIAI
CKLAIEHGLEPIFQMTCRDRNRIGLQSDLLGASVLGIKNVLCMTGDHVSAGDHKNAKPVY
DVESVQLLQIVDGLNNGKDMSGNELKGATDFFQGAVVTPEANPIEPQLMKFEKKVKAGAR
FFQTQAVYDIEKFKEFMKFAREFPVKILAGFVILKSAGMATFLNKNVPGIRVPQELIDE
>A0A3A0EFB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MADPRLSRRPDAGGRINVSFEFFPPKTDEMESRLWETVTRLEPLSPAYVSVTYGAGGSTR
ERTARTVGRILRETALKPAAHLTCVDATRAEVDAVIRDFAAMGVSRFVALRGDPVAGVGA
AYRPHLDGYSNGAELTAAIRRIGDFEVSVSAYPEKHPESADFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGILPIHNFRQVAGFAGRCGAHVPAWVAGRFE
GLEEDPQTHALVASAIAAEQVLDLVERGVEEFHFYTMNRADLAFAICHLIGVRPQTAAAA
>A0A4R4EZW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. N42|TrEMBL
MVPISFEFYPPKTPEQHAQLDKTVARLKAHAPEYVSVTFGAGGSTLSHTPETIQKLRAGG
FDAAPHITCMGGSREEIRGLLKLYRALGARRLVALRGDLPSGMVSAGEFRYADELVRFVR
EETGDHFHIEVAAYPEMHPQARDAQVDLRNFVGKVRAGADGAITQYFYNADAYFRFVDDV
RRQGLDIPIVPGIMPIANFSQIRRFSELCGAEIPRWIAQRMQAFGDDTESVRAFGAEVVA
QLCRRLLDGGAPSLHFYTLNLSKPTLNVLANLR
>A0A3E0MSX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MTDILANAKGCEFTFEILPPLKGQKAQEIFDNIDPLMEFKPPFIDVTYHREETVYKRLPN
GLLQEKVVRKRPGTVGICAALMHRYQTEAVPHVLCGGFTKEDTENVLIDLNFLGIENVVA
LRGDQAKGESYFTPKPDGNNYAIDLVKQINDLNQGRYLDEDLQNTMATDFCIGVAGYPEK
HFEAPSLNIDIEHLKAKVDAGADYIVTQLFFDNSKFFAFVDKCREAGITVPIVPGLKPLV
TKRQLSILPQIFHVDIPDTLAIEVLKCKDNAEVRQVGIEWCIQQSKELKDAGVPVLHYYS
MGKSKNIYEIASAIF
>B5JTS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium HTCC5015|TrEMBL
MSDRHFSFEFFPPKTDRGREKLLGVHRELAELNPEFFSVTFGAGGSTRDGTLDTVTAIQE
RGSAAAPHISCIGSSKSEIDQLLNTYQERGINRLVALRGDMPSGQYAAGDFAYANDLVEH
IRTTTGDHFHIEVAAYPEFHPQAKNAEDDLTNFVRKVNAGANSAITQYFYNLDAYLRFVE
AAQGRGVEIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKRLEAYGDDSDSIKAFGQDI
VTQLCSDLLDNGAPGLHFYTMNQTEPNRAIWQALNLG
>A0A227JKZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium zucineum|TrEMBL
MSPTSSALGPVARAGAGLPRHPSISFEFSPPKTPEAEESLWEAIRRLAPLNPTFVSVTYG
AGGSTRDRTHRTVVRMLRETNLKPAAHLTCVEASRTEVDEVVKAYWDAGIRHIVALRGDP
PGQIGGTYIPREDGYLNATELTKGIKAIGDFEVSVSLYPQGHPENTNLDKDIDVLKAKID
AGATRAITQFFYDIDGFLRFMDKVRKAGVTIPISPGIMPVSNFKGLKKMAAPVGITLPDW
LGNLFEGLDGDPESRKLIAASVATEMCASLAEEGYSDFHFYTLNRADLVYAICRVLGVRE
TPTEAV
>A0A3M2FKG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MHVTEILDRATEPLISYEIIPPRRGGTVEQVLAVVEELMPFEPPFIDVTSHSAEAIYEEQ
PDGTWKRRVMRKRPGTLGLCAAIKGRFGVETVPHLLCNGFTREETEDALIELNYLGIHNV
LALRGDDHGFQKPVSPDRSRNRYAAELVQQIAAMNRGEFLDDLVDAAPTNFCIGVAGYPE
KHFEAPNLAWDVLNLKRKVDAGAHFITTQMFFDNRRYFEFVERCRDVGIDVPILPGLKIL
TSKRQLQLLPGRFFIDIPEPLAAEVEAARPEHVVDIGVEWAIRQCEELMAANVPSVHFYI
MQTASVVKQVVTALRKMA
>A0A5P9GHI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria sp. THAF33|TrEMBL
MNDAHRSEVEPIGYVPVPEGYVSHSRLERVLRSGRFAVTAELNPPDSADPEDVFQAAQPL
GEVADAINATDASGANCHMSSIGICALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAALG
VSNVLCLTGDGVGVGDQPGAKPVFDFDSLTLLRTIRTMRDQGKFLSGRKITRPPQLFLGA
AENPCIPPYDWRPERLAKKVEAGAEFIQTNYIYDIPLFERFMDRVRDAGLDEKVFIIAGV
GPIASARAARWMRSNVPGIHIPDHVIERMEKAEKPAEEGKKICIELIQQIRDIAGVSGVH
VMAYRREHVVSEIILESGALKGRKRTRSS
>A0A6A2EXX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKITDHIKNANGETLFSFEILPPLKGKGIESIYQGIDPLMEFNPKFIDVTYHREEFIEKK
LPDGSYRKITTKKRPGTVAICAAIMNKYHVDAVPHLICGGFSREETENALIDLAFLGIDN
VLALRGDNAKGESSFKPEPNGNANALELLQQIQQLNKGVYLDDELADAFPTNFCAGVAGY
PEKHHDAPNLKSDMAFLKKKIEAGAEFIVTQMFYNNSRYFEFVDKCREAGINVPIIPGLK
PLTTKKQLYVLPNLFHMDLPEELTEAVEACKDDKQVAQIGIEWAVQQSKELKAKGAPVLH
FYTMGRSAATYAIAKEVF
>A0A3S5XV07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lelliottia amnigena|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRAIAQDYWNSGIRHIVALRGD
LPPGSGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVNAGIDLEIIPGILPVSNFRQAKKFADMTNVRIPLWMQKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J4YNZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis Delta 1 endosymbiont|TrEMBL
MPDENFMVTVEVVPPAGPDAAPLLAELEPLVDLAFDAFSVATNPVAKPRMSAMALSALLQ
QKTGKSAILHCTTRDHNRLSLQGMLWGARALGIATVLIATGDVIALGDRAQTSSVRDLDV
FDLVRMARSAGLRTGVVFDTHPESNGLEQAVRRLADKIEAGAQFAVTQPVYDEAAADHLF
EATQSLDIPVILGILPLRTARHAEFLHRKVAGIAVPQAVRSRMQRAADPVAAGIANAGQM
LALARRHLAGACLMPPFDHYEVLFEILKDKDRNDGL
>A0A6N8EPA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bombella sp. ESL0378|TrEMBL
MAEVSFEFFPAKTDEKAAALLRVAQRLAAYEPRFMSVTYGAGGSSRERTLEALRQMVEAL
PIPLAGHLTCVNAAKGEVDDVARVYWDLGVKHIVALRGDAPVAKGEAPTPYRPHPEGYHY
AADLVAGLKKIAPFEISVAAYPETHPEAQSAQSDIEHLKEKFDAGADRAITQFFFDPECF
LRFRDRAVKAGINKPIVPGILPIGKAAQAWRFAKMCGASVPEELKTLFEGVDDLPPIRTR
LSAVVVDRLCQRLRAEGVEHFHFYTLNQSVPTSTLCTLLGRQRSHPLVELAS
>A0A832MRN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriia bacterium|TrEMBL
MPPLQHIFDTSGFKIGVELISTRGTISQEKAKKTLYFGEQLCKQKSVDWISITDNAGGHP
TISASSIGKSLQSKGKEIIIHVTCKDANRNGLESKAWDLSSDGFSNILAITGDYPAPGIG
GTPKPVFDIDSVALLYLLNRLNNGLEIGKKKKLHLKKTNFFLGAVVSNFKKNENELIPQY
IKLLKKIEMGAQFIINQVGFDAGKMSELIRFQQYK
>A0A7G8EZG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. NOUM97013|TrEMBL
MGSALQRSLEAGSVTITAEVMPPRGGDPSHALAMAELMRGWVQAINVTDGSRAVMRMNSL
AVCRLLLDAGLEPVLQMAGRDRNRIALQADLLGAHALGIRNLLCLTGDPVQAGDQPRARP
VHELESIRLLKQVSAFNRGEDPVKENLPDGPTDLFAGAAADPHCPSWSGLTRRLERKREA
GARFLQTQMVMDPRVLERFCQELAAPMELPVLAGVFLLKSAKNAAFINRMVPGACIPEDL
IARLAAAEDPASEGITIAAEQVRQYLGIAQGVHVMAVRAEERIPEVLKRAGLSSQPV
>A0A7L4WST0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. YLB-09|TrEMBL
MGFHHAQHATSLNQSLAELNGDINVSFEFFPPASPEMEKILWNSVRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETDLVAAPHLTLVDASDEELKELAKHYWNTGIRDIVALRGD
LPEGSPRPTRFANDLVRLLRSVADFDISVAAYPEVHPDARNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFKQLKRFAGMTNVSIPSWLHKQFE
GLDDDPATRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGR
>A0A543Q524|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus thiooxidans ATCC 19377|TrEMBL
MAHSVEFFPPKNAAGEQRLQEAIRALLPLKPEYASVTFGAGGSTRERTFATVDMIRKDYA
LEAVPHLSCIGSTESGIQEILEDYRTQGIQRIVALRGDLPEGMSNPGHFEYAADLVGFIR
QFGGFKIYVAGYPEVHPKAVSAEEDLQHLVEKVQAGADAVITQYFYNPDAYLQLRDDLQR
RGVEVPIVVGVMPITNFEQISRFSAMCGAELPQYLRRRMEAYGEDLQSQYQFGIELLSRQ
CETLLAQGAPSLHFYTLNQSEATTAIWQNLGL
>A0A0S8KPC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium SM23_84|TrEMBL
MIAGSNLEKVLRAGHFAVTGEIGPPASASREVIEEKAQYLKGNVDSVNITDCQTAVVRMS
SISVAVMLMQLGIEPNIQMTARDRNRIAIQSDLLGAWALGIKNLLCLTGDHQTFGNHPMA
KNVFDMDSISMLMMLKKMREEGVTESGDTMDVPPLFFLGAAANPFADPFEFRPYRLGKKV
RAGADFIQTQLIYNVPKFAEYMKRAGDLGVLDDVYILAGVGPIKSSGAARYMATKVPGMD
VPDEYVQRMADAISGIPKEDKQARTAAWHEQGIGICVEIIQQVREIPGVAGVHVMAIEWE
EAVPTILQRAGLLPRPVV
>A0A0B4X1M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium gallicum bv. gallicum R602sp|TrEMBL
MALNTGDRRDIGISFEFFPPKSEEMEGQLWKTVAELQDWDPDFVSVTYGAGGTTKAPTLT
AVTRFLNETPLATASHLTCVGATKEETHQVIDHFRKAGVKHFVALRGDAPGGAGVPYQPH
PGGYANAAELVAGLREIGDFEISVSAYPEKHPESRDVAADIDMLKRKADSGADRALTQFF
FDNDNFERYLEKVRAAGVKIPIVPGIMPIQNLTQLKRFASACGTVIPAFLDERFAGLDDK
VEERAKVSVDVAVEQIEDLVRRGLDEFHLYTMNRSPLVSAVLTNLGLRREGAKRAAGAAA
>A0A218PNH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp. GJ21|TrEMBL
MAQGNERKSKLLGSGDIVVSFEFFPPKTEKMDETLWSSISRLAPLRPEFVSVTYGAGGST
RERTHATVTRLLRETDLKPAAHLTCVDASKEEVDAVARAYWDAGVRHIVALRGDPAQGAG
TKYEPHPGGYTNAADLVSGLKKIANFEISVAGYPETHPESPSVEADIENLKAKVDAGADR
IITQFGFDNAHFLRYLERARAAGIWVPISPGIVPIHNFKQVSGFAKRAGATVPSWLARRF
EGLEDDPATTHLVAAAAATEQVMDLVDEGIKKFHFYTLNRADLVYAICHLLGLRSARTDA
SANAA
>A0A3D0S2S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp|TrEMBL
MAPIPGRSIRELLEHGERSFSFEFFPPKDEAGEQQLWQAIEALEPYRPNFVSVTYGAGGG
TRDKTIAITSRIARETSLTPVAHLTCVGHTRQELERILDTYAAEGIAHVMLLRGDPSDGP
RAPWTPTEGGLTYAIELVELARSRGDFHIGVAAFPEAHPSAVSREADADVLVAKARAGAE
FAVTQMFFRASDYFDLVERVRARGVEIPIMPGIMPILNLNAIRRQGELIGTDVPDDVVAR
VAAHDGDPAAMRAEGIALAAELCEELLAGGAPGLHFYTLNRSKATLEIFAALNVTV
>A0A286APM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. YR752|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYVRKPQFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFLYASDLVAFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSAEAYFRFVDD
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASIKAFGLDVV
TDLCARLRDGGAPALHFYTMNQSAATLAVLERLD
>A0A1K1P9M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulophaga fucicola|TrEMBL
MKVTDHIKNAKGKTLFSFEIIPPVKGRNIQELYGNIDPLMEFKPPFIDVTTSREEYIYID
RDGLLDKKLTRMRPGTVGICASIKHKYDVDTVPHVLCGGFTREETEYLLVDCHYLGIDNV
MALRGDAMREEQYFEPTKGGHQYAVSLVDQIQKLNCGSYLHEVIETDNCADFCIGVAGYP
EKHIEAPSLLTDLKRLKQKVDAGADYVVTQMFFDNEKYFSFVKAAKDFGINVPIIPGIKP
IAVKRHLQLLPQVFKIDLPQDLVDAVEDCKDNKSVRQVGIDWAVQQSKELKAAGVPVLHY
YSMGKSDNVKAIASQLF
>A0A2S7IP36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Siphonobacter curvatus|TrEMBL
MKVTEYIQQANGKALFSLEIIPPLKGQSVTELFDTIEPLMEFKPPFVDVTYHREELIEKR
HPSGLIQKVPVRRRPGTVGVCAKLMERFKVDAVPHVICGGFTKDETEDFLYDLHYLGINN
VLVLRGDPEKSAGVFKPKEGGHAYATELVEQVVDMNHGRLLHEETEAQPTNFCIGVAGYP
EKHFEAPNHSNDLRYLKKKVELGAEYIVTQMFFDNQKYFDFVKRCREEGITVPIIPGLKP
ISTKKQLTVLPRIFHLDFPEELVHAVEACKSDKEVREVGIEFGIQQCKELLDFGVPVLHF
YTMGKSDSVQRIARAVF
>A0A4P7PP47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas viciae|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTRYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLLNFVRKANAGANSAITQYFFNADSYFY
FVERIRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1F9DE20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_54_18|TrEMBL
MKIHEIIKRKGKSVSCEFFPPKDQAGEDKLLVVIKQLEALGPDFVSVTYGAGGGTRKNTM
SLIKRITEATALTPMPHLTCIDQSKKELKSILDNYRLLSVDNVLALRGDPPRGQIEFVAP
KDGFCYAKDLVDLAATFNSFSIGVACYPEGHIEAPNRETDLLYTKQKIDAGAHFAITQMF
FENRFYYDFLERAGKIGISVPIIPGIMPVTDMKKTGQFCEKCGATIPASLAARMESASPE
DCRRIGREFAIEQCADLIKQGVRYFHFYSMNQAEAVTEIFQSLSLHTL
>A0A009YK73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 479375|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKIVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTAVAPHLSCIGDDKGRIAKLLDLYQSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAETFDADIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERLEKEGITIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A659F0G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT2-23|TrEMBL
MSTTSEPDCGRIPFSFELYPPRSDAAATALHATIATMASAGPDFISVTYGANGSSRSSSL
EVLTHILKTTTVDPMAHLTCVGSSSLEASRLIREFLDAGVRSFLALRGDPPEGAGEGEAF
LGDLGSAAELVQLIHRVQAERVPYRETVIPGIPGARAVKTEREKVRIAVAAFPNGHPRSR
STSQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRARTAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIQLEVEPTREGQREIGTRHATDLARELIAGGAPGLHLYAFNQAD
TVLAVLAGAGLIKPVLG
>A0A6B3RSN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tabrizicola algicola|TrEMBL
MATPRISFEFFPPQTLDASFRLWETVQALAPMQPEFVSVTYGAGGTTRKLTHEAVTAIGK
NYGLNVAAHLTCVDATKAETLEIAAAYAEAGVTEIVALRGDAPKGAERFTAHPDGFASSV
ELIEALAATGRFTLRVGAYPEPHPDAADTLADVRWLKRKIDAGASSAITQFFFDADTFFR
FRDLCVKEGITAPIIPGILPITSWAGAKKFAQRCGSHVPARLDEAFTTAARDGREELYAL
AHCTQLCDRLLEGGVQDLHFYTLNRPHLTREVVRALGIQPEVVLEKVA
>A3LUC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)|TrEMBL
MKISDKLSQAHSSANPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALHKAFESGCQNILALRGDPPLD
GSESTGDFKYAKDLIEYIRRKYGDHFNIGVAAYPEGHPEEDSEAKTLEYLKEKCDVGADF
IITQMFYDVDNFISWCSKIRKIGVNIPIIPGIMPISTYAAFVRRAKWSQIAIPPHFLEVL
EPIKDDDYLVREKGTELVSQMCTKLLQSGFVNHLHFYTMNLERATIMILETLNIIEPVKA
HENTGGDELPWRKSLHPQRSKETIRPIFWQNRKYSYITRTATWDEFPNGRWGDSRSPAFG
DIDLCASELLRQSPKKAYDLWGTPQTLKDFSDIIVSYLQGELKSLPWSDGPIGEDTSVMV
ENLINLNHKGFLTMNSQPALNAVKSSEKVYGWGPKNGYVYQKQYLEFFCPKDLLPKLLHT
IDSYNKSEGDASSSIISYYAVDKNGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSF
LAWKDEVYRLFTEWTNILQSNLVDADKDKISGFVDLITNFSNNFVLCNLVNNDFIDKNET
LFNLIETVASEGN
>A0A7C4PG54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSDFITALSAAESPLLGDGAMGTQLNARGIGFNQCFDQLNLSQPELVAGVHRAYIEAGAQ
IIQTNTFGANRFKLAAFGIAHLLAEINRAGVELARQEAQISGRAVLVAADVGPLGVRLAP
YGRVRVEQARQAFAEQIAALAQAGVDLLILETFSDLQELLTALDAAHQVCDLPVVASMTF
TRDDRTVLGDTPAAAAGALARAGADVIGVNCSGGPAQALRLLQSMRQALLAQADVALPRF
SVMPNAGWPEQVGGRMMYPAHPEYFGEFAMAFCQAGASLIGGCCGTTPAHIAAMRAALDS
RGANCAPLPEQASITIEAEEQAAQPEFPSRLAEKLAAGKFVTAVEMDPPRGLSAHKLLAG
ASLLAEAGVDVINVADSPMARMRMSPWAVCDLVQRTLGVETTLHFPTRGRNLLRVQGDLL
AAHALGIRNIFVVMGDPTAIGDYPDAMDNYDLVPSGLIRLIKRNFNLGRDHAGADLGQPT
SFFVGCALNLTPQDPLQEMKSLQRKARAGADFILSQPVYKPEHARRFLEEYQERYGSLNI
PILVGVLPLLSERHATFLNNEVPGVSIPPLMLERLRQAGESAPLEGVRIALELVEEMRAW
ASGIYLMPQFNRFDLAAEIIEGLR
>F0G0Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. TJI49|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATRTICERLDT
>A0A6L9IW31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
PVLVSVSDVAASAVEDVPEQPTLLARKLSIGDFVVTVEMPPPRSFTAQKVIASAELLREA
GVDFINVSDSPMARMRMSPWAVSYLIQHHVGLETVLHFPTRGRNLLRIQGDLLAAHALDV
RNVFVVMGDPTRIGDYPDSFDTHDIVPTSLIKLIKYKLNAGMDEAGNSIGQPTSFLVGCA
LNVNARDVDREIRLLRKKLDAGADFALTQPVFDVDVLDRFLETYAAQHGPLEIPVLAGIL
PLYGTRHARFLHNEVPGIDIPDVIQVRMADAGDDAQNEGVRIGQELLLRIRELAQGAYIM
PAFGRYDLVAGVGDALERTPSSSV
>A0A0K2SML9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnochorda pilosa|TrEMBL
MTGPEPGRDTLGTAFRQALAERVLLADGGVGTLLYQRVGGPRGNLDALNLTQPRVVEQVH
LDYIRAGADLIETNTFGANAFRLAEYGLEDDVWRINLQGAKLARGAREVSGRPVFVAGSV
GPVGRPLETLGRAARAYVRDAFLRQMEALLAGGVDLFMIETMLDVEELELAVEAARSLAR
LPVVAQITFSGGVEPVAPLQGEAFTRMVERLGEAGPDVAGINCGSGPGPVLEALGELAGL
RALGVPLSALPNAGLPTRVDGRILYGAAPEYLAGLVEPMLRQGVRLVGGCCGTTPEHIAA
MRARLDTLQPARAAGPADEGEHAHPARVAPAEVRSPKTEAAVPAAPAASPLLEALRRGEM
VSVELDPPRGVNVEKVLQNARILQEAGVTCINVADSPMARVRMASLASARLILEATGLPP
LIHFTTRDRNLMGIQADLLGAHALGIRHVLALTGDPPSVGNYSHASAVYDVDSIGLVRIL
HTLNRGRDLAGNAIGEPTAFTVAVALSPNAADPDLEARRFREKLEAGADFVMTQPLYEIE
PLVAMLERAGGCPVPLVLGVMPLQSHKHAEYLHNEVPGIRIPLRVREEMARAGEDGARVG
MELAARVLEDARGFIQGCYVVPSFGRVEQVAGLVRELRRRGGWATPAPAVSR
>A0A536BGE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAADKKRSNPFLERLRRGPLLGDGAMGTQLHARGVSFQRSFDELNLTEPEIVEEIHRAYI
SAGAELIETNTFGANRIKLARHGLDGRVRDINVRAVKLAREAREIAGEPVFLAGSVGPIG
QQLEPIGRISIAQATAAFEEQIAALLEGGADLLVLETFTNLPELLAAVAAARRTADLPIV
AQMTFAEDGLTLSAEEPSQVVQALERAGVDVIGVNCGVGPQVALQVLEGMRQQTRLPLSG
QPNAGLPARVEGRFFYFATPEYFATFARQAADLGVAYIGGCCGTTPAHIAAMRAALKPVA
TSARIQRPAPSTAIAIDLNPAEQLPPTPFAQRLAASAFVVSVEIDPPRGLNPAKCIAGAE
LIKAAGADAINIGDSPMARVRMSALSLALMIRQQVGIDTLIHFTSRDKNLMALQAELIGA
HALGIRNIIALTGDPPRIGDYPSATGVWDVDSIGLIKILQRLNEGYDWLGTSIGKPANFT
IACAVNPSADDLDNEIDRFRQKIEAGAHVAMSQPLYDRHTLERFFERTGPLPIPFLLGVL
PLQSSRHAEFMHNEVPGIVVPDPLRERMRRAGENGIVEGLAQSRELLQDTKDLVQGVYLM
PSFGRYEVVAELVRWLRQELVTTGQPSLP
>A0A7C2UCJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MDDPLPSPGREATLDARALTLREKLAAGRFVVSVEIDPPIGLAPRRALRAAALMKEAGAD
AINVGDSPTARVRMSPWALCILLQREVGIETVMHYTTRDRNAMAIHSDMVGCHALGVRNV
LCLRGDPPELGGYKDVIGVWDVSAVGLIRILKLLNEGLDWTGRPIGRQASFLIGAACNPN
ADPLGPEIRLMRRKVEAGAHFFVSQNVFDPDRLERFLEQAAPFKRPVIVGVLPLHSYEHA
QRLHREVPGMYIPEEVRERLRRAGPDAPREGKAIAREVMELCRSRAAGVYLVPTYGNYDL
VAELVAEGRG
>A0A521HZE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPDSFLTRLAQAPLLCDGATGTLLYVHGVAFEQSFDALNLEQPALVQELHEEYLRAGAEV
VETNTFGANRFKLQEHGLEHRVAEINAAGVRLARAAVNASGKNAFVAASIGPLGIQIAPV
GAVSRQEAHDAFREQIAALASEKPDALIFETFGNLQEITEAIRAAQELASPIPIIAQMTF
TNDGVTQYGYTPVQVAHALAALKVNVIGVNCSVGPARIFPVIEQIIHTVRDDPRRPGMIY
FSAQPNAGFPEASGGRIFYPATPDYFGDYARRFAEAGVNLIGGCCGTTPQHIRLMRLALD
AYARTAKKRPRITSIASNEPETKPLAHEPPTQMQQKLDAGHFVVGVEMSPPRGFNPDKVL
AGALILKQAGADVINVADSPRAQMRMSAWAVAHLIQTEIGAESVLHFPVRGRNLLRVHGD
LMAAHALRVRNIFACMGDPAATGDYPQATDAYDIVPSGLVKLIKQHFNEGIDHAGTSIGA
PCSFTAGVACDPNARDAAREIKTLRKKIEAGADFCLTQPIFDLAVAREFLKQYADEYGKL
ELPMLAGVLPLASSRHAEFLHNEVPGITLTDEIRERMRRAGDNGRAEGLKIASELWSELL
EFAQGVYIMPAFGRYETVAELLEQVKVRA
>A0A7C1PEN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSRPWSPSQPERSLDLGALLRTRVVVCDGAVGTMLHAAGASLDLPLPELSVSRPELVRAI
HGAYIEAGADIIETNTFGATRTRLARHGLGERVREINLAGVAVAREAVMAASRRVLVAGS
VGPATPPGSRRRLSPVILREAFREQIAALAEGGVDLLILETFGSLEELLEAIASAEEVAP
NLPIVAQMTFLDDGRTLAGETPAEVAARLDGLDLVAIGANCTLGPQGLLEVLREMGHHTA
LPLSAQPNAGPPTFVDGRFRYTADPAYFARHARRFVELGAAIVGGCCGTTPAHIEAVAGA
VRGMQPVPRHPIPSATPRTRSHGAEKPYSPPSRLLERLAARRFVKVGEIAPPAGGAAEQV
VQEAALLKAAGCDAVLIGPPSSVRAQVSPASLAVLVQQQVEGLEAILTVTTWEKSVMALQ
ADLLGAHAFGVRHVLCRTGTPPLVGDYPNAGGIWDVDSLGLIQLLRGLNEGRDHHGVALA
RPTGFVIGARINPSAEDPEREIADARRKIEAGVDFLITPPVYDLDAFDRLLDAIGVPEDL
PILLGVMILKDFRHAEYLQHEVPGMSIPEPILERMWLAREDGAEVGRAIARELICRARAQ
GRIRGVVLSSAVGSAEGVARLLRELPP
>A0A3M1HEU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGIFSPRRYQAPFYPYSRAGESVGERAFTAFERVVKGALFSCRMCGNCILQETAFVCPMT
CPKGLRNGLCGGATPEACEVDPTRPCTWYVIYERSEKLGREHKLLEINAPLDGARVGKET
WLDVYRTWRKRGGPKPLDFFFNREKFNQEYEALFYEIRQPDWWQGDSDYHPPKYEEPVSL
LEANLKSGAFTVTAEIAPPLTADTSSIAKKVDWLKDWVAAANFTDNASASARMGSLASSK
ICLDLGMEPVMQLQARDRTRVVIESDAMGASGLGIRNILCLTGDHHRFGPPPMSKPDQFD
LDAVQMLWMLRRMRDEGVYIDGRKIKVPPVFFLGAAASPFGAPPKYEAIRAEKKVNAGAQ
FIQTQPIFDYNRFLEWLEALDKRNLLDKVYILAGLIPLKSARAAHFMAEDVPGVYIPPEY
VKRMDEAGDKEGQQEVGVQIALEIIDKLKNTPGINGLHIMAVHWEQIVPRLLEEAGIPKP
AIRSLSSAETPSEPAPISG
>A0A6N9JQR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens|TrEMBL
MRVDEVFKQTASQGTTPVSFEMFPPKGELTLDTARKVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNVSIEHLKQKQDAGASFFV
TQLFFDNEYFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A536I2G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAAEKGRSHPFLERLRRGPLLGDGAMGTQLHARGVSFDRSFDELNLTESKIVEEIHRAYI
SAGAELIETNTFGANRIKLARHGLDGQVRDINVRAVKLAREAREISGEQVFIAGSVGPIG
QQLEPIGRISIAQATAAFEEQIAALLEGGADLLVLETFTNLPELLAAVAAARRTADLPIV
AQMTFAEDGLTLSAEEPSQVVQALERAGVDVIGVNCGVGPQVALQVLEGMRQQTRLPLSG
QPNAGLPARVEGRFFYFATPEYFATFARQAADLGVAYIGGCCGTTPAHIAAMRAALKPVA
TSARIQRPAPSTAIAIDLNPAEQLPPTPFAQRLAAGAFVVSVEIDPPRGLNPAKCIAGAE
LIKAAGADAINIGDSPMARVRMSALSLALMIRQQVGIDTLIHFTSRDKNLMALQAELIGA
HALGIRNIIALTGDPPRIGDYPSATGVWDVDSIGLIKILQRLNEGYDWLGTSIGKPANFT
IACAVNPSAGDLDNEIDRFRQKIEAGAHVAMSQPLYDRHTLERFFERTGPLPIPFLLGVL
PLQSSRHAEFMHNEVPGIVVPDPLRERMRRAGENGIVEGLAQSRELLQDTKDLVQGVYLM
PSFGRYEVVAELVRWLRQELVTTGQPSLP
>A0A7C4LGN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLKSGRFAVTAELNPPDSADPQAVYDRVLVLSTVADAINATDASGANCHMSSVGICALLT
RAGYEPVYQMSCRDRNRIAMQGDLLGAAAMGVKNVLCLTGDGVQAGDQPEAKPVFDLDSM
TLLRTVRIMRDHGQFLSGRKLDVPPRVFVGAAENPFAPPFDFRPLRLKKKWEAGAEFIQT
QYCFDVPRLREFMQRVRDLGLHEKLFILVGVGPLRSAKVAEWMRAHVPGVHIPEDVIARL
KGAQKPAREGKQLCIEIIQQVREIPGVAGVHVMAYRQEELVAEIIEDAGLLPRRPQPEPA
KAPGPM
>A0A3G4QVB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus debuckii|TrEMBL
MNRFLQTLKENVLVADGAIGTILYSEGIDTCPEAYNLTHPHKIERIHRSYIQAGADVIQT
NTYGANFEKLQTFGLEHRVKDITRAGVRIAKKAADEDTFILGTVGGFKGVQQNELSLSTI
LYHTDIQIETLIDEGVDALLFETYYDLNELLQVIRATKKKYDIPVIAQLTASNTNYLQDG
TEINEALKQVEAEGADVIGLNCHHGPHHMQQSFTHIELPQHALLSCYPNASLLDFENSSI
KYSDNATYFGKVAKSLVKEGVHLIGGCCGTTPEHIHYIKEAVEGLKPINEKKVIPIRRKS
NHPSIPVRKDNLTTKVKAGPTVIVELDTPKHLDTTKFFANVTKLDKAKVDAITLADNSLA
TVRVSNIAAASIIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKV
GHLPGATNVYDVNSKGLTELAVRFNQGLNIDGGALKTTTNFNIAGAFNPNVRKMEAAVRR
LDKKVDSGMNYFITQPVYTVERIQEIAEKTAHLDAPFFIGIMPITSYRNAQFLHNEVPGI
TLPEEILEEFEAVQHDKQKTKELSLKICRELVDEVTKHFNGLYLITPFEQVDYSLELATY
FKSKTESNQEAII
>A0A6N8Z359|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIRKILREKRTVSCEFFPPREEDGIPGVFRAIDRISAFNPDFISVTYGAGGSTRDFTER
ITMQVKQETDLEVMAHLTCVAQTRDEVHSVLDRLDQAGVENVIALRGDPPRGQENFVATE
GGFGHATELIDHIRANFDFGLAAACYPEGHTESPDLDSDIRFAREKVDRGADFLITQLFY
DNRYFFEFMERAHRAGINVPVIPGVLPILNTAQIRRFTSLCGATIPQELDNKLDRFAEDD
NAVRDLGVEYASKQVEELWENGVPGVHFYVLNRSYSVSRILANLDLPGHSVPD
>A0A535J441|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNERERFAERLAVAPLLADGGMGTLLFSRGLPQRACLDELATTRPDLIGSIHREYLEAGA
DLIETASFGANRIRLAAYGLAHEAHRFSRRSAQVAREARDVSGREALVGGSVGPLGAPTR
ELVHLDDARVRTAYREQLEGLLEGGIDVFVIETHVDLRHLLLAVEEARRAADLPILAELT
FGEDLTLPDGTTPEAAARALAAVSVDAIGVNCGVGPQACLDAVEAMGRAHDVMLPRSIMP
NAGLPQRIEGQFVYAAGPEYFGGMVSRFVRGGARIVGGCCGTTPEHIAAMRVALDAGAGA
TTTTAAASRTTAVRPVASDLPQHAGDALPPTQLATKLAAGRFVISVEIDPPRSIRIDRTI
EAARLLRSAGVDLVNVSDSAMARVRMGAMAVAFGIQHDLDVECLVHFTTRDRNLMAIESE
LLGAHALGVRNILALTGDPPRVGEYPTGTGVWDVDSIGLVEILARLNRGEDQAGSAIGQR
AGFTIACALDPTAADQATEWDRLARKLDAGGHLVMTQPLYDLAQVEAMDREARRRFGPRG
FPVPLLLGILPLQSTRHAEFLHNEVPGITIPDAARKAMAAAGERGAEVGLEMSLELLEQV
DSLVAGTYVMPSFGRYEQAAELTRRIRATHDARAAAAR
>A0A535TMA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPHRSNSGWPTLLHPPGGPSLPCPRAGGDKFGPSTLLLRSVAQASKNPASRVHPFLERLA
RGPLLGDGAMGTQLHARGVSFERSFDELNLTEPKIVEEIHRAYISAGAELIETNTFGANR
IKLARHGLDKRVRDINFRAVKLAREAREIAGEPVFIAGSVGPIGQQLGPIGRITVAQATA
AFEEQIAALLEGGADLLVLETFTNLPEILAAVSAARKTTDLPIVAQMTFAEDGLTLSAEE
PSQVVQALERAGVDVIGVNCGVGPQVALQVLEQMRQQTRLPLSGQPNAGLPARVEGRFFY
FATPEYFATFARQAADLGVAYIGGCCGTTPAHIAAMRAALKPAASPTRITMPAPSNAIAI
DLNPAEQLPPTSFAQRLTDHAFVVSVEIDPPRGLNPAKCIAGAQLVKDAGADAVNIGDSP
MARVRMSALSLAVMIQQQVGTDTLIHFTSRDKNLMALQAELIGAHALGIRNIIALTGDPP
RIGDYPSATGVWDVDSIGLIKILQRLNEGYDWLGTSIGKPANFTIACAVNPSAEDLDHEI
DRFRQKIEAGAHLAMSQPLYDRQTLEKFFERTGPLPIPFLLGVLPLQSSRHAEFMHNEVP
GIVIPAQLRERMRLAGENGIAEGLAQSRELLHEVKGVVQGVYLMPSFGRYEVVAELVRWL
RRERVTSPS
>A0A7X4BVV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0661_bin_20|TrEMBL
MHIAEVFRQSQPAISFEFFPPKSEAASESLFHTIQKLIPLKPAYVSVTYGAGGSTRDLTH
DLVVKLHNETNLTIVSHLTCVQSSRDEIFRILQRYDEHSIRNIMALHGDPPSQEPCDPSG
QDFRHAVELVAFIKKHFPHMGIGVAGFPEGHPDTPNRLQEIEYLKAKVDAGADYVCTQLF
FDNRDFYDFCERCQLAGIHVPIIAGIMPITSLQGMKRMAELALGARFPGRLLRALASAKD
DAQAEKIGIHWATEQVLDLLDNKVLGVHLYTLNKSRASLQIYETLGLQRVDMLME
>A0A7C2YDY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGDPLPPSGREATLAAGPLTLRDKLAAGRFLVSVEIDPPVGLDARRALRAAALMKEAGAD
AVNVGDSPTARVRMSPWALCLLIQREVGIETVMHYTTRDRNAMAIHSDMVGCHALGVRNI
LCLRGDPPELGGYKDVIGVWDVSAVGLIRILKLLNEGLDWTGRPIGRQASFLIGAACNPN
ADPLGPEIRLMRRKVEAGAHFFVSQNVFDPDRLERFLEQAAPFKRPIIVGILPLHSYEHA
QRLHEEVPGMYIPEEVRERLRRAGPDAPQEGKAIAREVMELCRGRAAGVYLVPTYGNYEL
VAELVAEGKG
>A0A6M0C702|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO2H7|TrEMBL
SGDPVKAGDHQDAKSVFDFESVRLLQAIDKLNHGVNWNGKKLADGPTDLFAGAAVDPQSP
SKSGLKKRFENKLLAGAQFFQSQLITDFEKLEKFMNEVAVETDKPILAGIFLLKSAKNAA
FINKYVPGVNIPESIINRLENAEKPLEEGMKIAAEQVKMVGGICHGVHLMAVKREDLIPQ
ILDLAEIEGIN
>A0A6B0Z3F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPSDEDSLAPNSGITARLSDGFKVAIEIETSRGLAMEEGARHSVDLAKAASQGGRVDAVC
FTDNPGGNPHITPETLGRELLDGDAEVVINLSCKDYNRNALEGRLWSLSSLGFRNVLCLS
GDYPVDGFSGQAQPVFDTDSVGLLELIRRMNEGLRVTLPGRRNAETELGHTAYHPGAAVN
PFKLYEGEYLTQLYKMDFKLRTGAEWLVSQIGYDARKHHELIRYLNLKHGEAAPPILGSI
FVLSAPAARFFGRWGIPGVAVNSELVDVANRAAKSKDRGRAFFNEFAAKQIAVLRGTGYS
GVYLSGRLTYKRIEQILDIAESITGDGWKDAAAEIGYSQPDEFYLFEPGDSANTASDKLN
REYDTRRGRPASILRRALHPDFAYRIGRFGKHAIFDHDAPGFNASAAVYRQIDKSKIATK
VAHAAEQMMKVPLYGCRDCGDCSLPEIAELCPESQCVKNQRNGPCGGTRAGKCEILDKDC
IYLRAYNTLKLYGEEEDMLNHPVTFTDSSLKGTASWANTFLKRDHYAKE
>A0A178YFY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium saheli|TrEMBL
MSPDINPLDPSAPLDPLPGHTSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSVIKRLEGAQDQKEEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRRPWKPETTPTDALVAERLEHLREGVEENQQQMAEAAAH
HPH
>A0A3M1ENP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTELAYSMRSGGRLERVLRSGLFAVTAELNPPDSADPQAVYDAALVLAEVADAINATDAS
GANVHMSSVAICALLTRAGYEPVLQMTCRDRNRIAIQGDLLGAAAMGVHNVLCLTGDDVT
AGDQPQAKRVFDFDSIQLLRTAKIMRDEGMFLSGRKLDVPPRLFLGAAANPFVPPYDWRP
RRLAKKVEAGADFIQTQYCFDVPRLRQYMQQVRDMGLHEQVYILVGVGPLRSERAAEFMR
TRVPGVVIPDEIVDRLRKTPQEKKRDEGKRICIEIIQQVREIEGVAGVHVMAYRQEELVA
EIIQESGLLPRRKRHDVPRAPEGELEMLARQASTTQVD
>W5IPB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. (strain M1)|TrEMBL
MTTSDRRFSFEFFPAKTEAGHEKLLATARQLAGYKPDFFSCTYGAGGSTRDRTLVTVLQL
DGEVNVPTAPHLSCVGDTKAELRALLAHYKDAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRAETGDHFHIEVAAYPEVHPQARNSEHDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAQKLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIASIQSF
GEQVITEMCERLLDGGAPGLHFYTLNQADPSLALWKNLKLPR
>B1LNQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli (strain SMS-3-5 / SECEC)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2E5NW96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLIKDILKTSRTISCEFFPPKDSEGIXXVLEVAGRLKXYNPSFVSVTYGAGGSTQAFSEE
ITLRLKRELNFEVMAHLTCVSQTQSEIDEVLERLVSAGIENIIALRGDPPAGDSNFVPVE
GGFAHASDLIKHIDHKFSFGIAAACYPEGHTESIDLYSDIQYAKLKVDNGADFLVTQLFY
NNQDFYDFVERAXKSGITVPIXPGILPXLSAPQIRRFTSMCGASIPVQLDTQLDKHHDDD
KTVRQIGIDHAINQVQDLWANGVQGIHFYVLNRSYSVSKILDSLQIPDHTGLSKTTT
>G2DES0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|endosymbiont of Riftia pachyptila|TrEMBL
MGAGRDVAVWQESSMTSQTKTAPSISFELFPPKTGQGFENLKRTISQLNQAKPEYFSVTY
GAGGSTQERTFASVDWLREQGIETAPHLSCIGASVEETVAILQHYRDQGVNRIVALRGDL
PSGAGLGALGELNYANELVSLIRERFGDQFRIEVAAYPEFHPQAPNPETDLANFKRKVDA
GADSAITQYFYNPDAYFRFVDECSRLGVEIPIIPGIMPITNYSSLVRFSDACGTEIPRWI
RKRLEGFGDDLESIRAFGLEVVTELCRRLLEGGAPGLHFYTMNQSEPTLRLCDRLGL
>A0A2E1W9E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MXIIDIINKKQTLSFEFFPPKEKSNIGNLNKTIDDLSEFXPDFVSFTYGAGGXTRKLTLE
ISAKTKNSDFSSEVMSXXTCITHTENEIXEILNNYEQSXIEXIIALRGDLPHNSNEXKNX
IPHATDLIEIIKNHSNXFCIAAACXPESHPXSLSEEXDXSXIKXXQSKGADFLIXQLFFN
NNDFFKFRDKAIKSGIKIPIIXGIMPITXTKQIRKFTEMCGASIPDSLXKKLETSXNNDE
ETTKFGIEFATNQIKELLENNIDGIHFYSLNKSRSVKEVINNLNI
>A0A2W5XK94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLSTPRGWVEMVEINPPRLPSMTHLDLRDSWREVLITDNPFKQVRVSPYAFAARITHDVP
DVRPTVVCSTRDRNILAIESEVRGALVNGVDSFLVVQGDMLPEVEHWSNSYEIVEHLRAL
QEKTPPFEVGMSTRSRSWMLRRRVQVGAQFLTTGPVMDPAAVAPCAERLALRAGDPPVYL
EVTPPFSPEWVQRLERVGAIGIGDALRSRLERTADSERRRLGWQLAKAVAVRARQYGFAG
VVLMGLRFETVIGEAFDAWHDDEVEPLDVELPIEPATR
>A0A2E1IW30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKKFSIEILPKQKSKILELNSDFFEDVYITHIPGSSLNDLIDTAKEVSVYGLNPVPHIPA
RSITNENLLNETLXSLKEVGVXDILAIGGSVKEKXGKFDSTLDMFSTGALNNIGFKSVRI
AGHPEGNPDDKNSIQSLKNKLIWLKENKFSASIVTQFCLSPEITNDWIMETKKLIKDFGE
DGTKIIIGVAGPSKITTLIKYAKVCGVSSSANFLMKXGLDVTKLIKHSPTDLIEKLDGFD
SLHFFPFGGIKELDDWLSKQK
>A0A3N4Q850|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga lutea|TrEMBL
MKVTEHIAQANDTLISFEILPPLKGKSIESIYDHLDPLMEFKPSYINVTYHRSEHMFKKR
ADGSFDKVEIRKRPGTVGICAAIMNHYSVDAVPHLICGGFSKEETENALIDLNFLGIDNV
LVLRGDAPKNETFFEAHPNGHRYALELLNQVVQMNNGIYLEEDLMGGIKTKFCIGVAGYP
EKHFEAPNLQTDLGYLKRKVEAGADYIVTQMFFDNQKFFDFVTRCREAGITVPIIPGLKP
LTTKKQLSVLPRTFHVDMPDEFAQEVMKCKTDKEVETVGTEWLIQQSRELKAAGVPVLHY
YTLGKPHVVQQVVAAIK
>A0A536PLJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MISDLPGGRPRRAVRTPSRLAGLLHAGRFVVTAELSSVDSGEPEAVWRRVEPLRGVVDAV
NCTDNTGAHVHMSSLAAAHLLVEKGIEPIMQLAARDRNRLALQADLLGAAALGVRNILLM
SGDDVTAGDHPEARSIYDIDSLQLLQVARNLRDRGTYLSGRRLESPPVFFVGAVENPFAP
PLDFRPFRLQKKVEAGAEFIQTQLVFDLARFHAFMGRVEDLGLLERVFVIASIGIPRSAR
GTHFMKEKVPGLSVPDDVIRRMESVPPLQQPAEGIRIAIELVEAVRSIRGISGVHLIGIK
WEEGVVRVAQGAGLLPRPVAEVVATVGGGA
>A0A535RE42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSSLASLLRSGEFVVTAELNPPKSAAAGVVRRRAEALKGVVDAVNVTDSNRAMVAMAAIP
AATIVRSVGLEPIVQMTGRDRNRIALQADVLGAAAIGIENFVFMSGDDPKQGNHPDAVFV
KDLDGVGLVKMAVGMRDGAQFLSGDEIKQPPKMLVGATASPFTKPMEADVTKTLEKIAAG
ADFLQTQPVFDLATFSRWLVEVRRSASREVPMLAGVLILRSPDQAERLARVPGLAIGPEV
LDRLKKAADAEAEGIAIAVQMVKALKALPGVRGVHLYAIEWPEAVARVVEAAGLLPRPDA
RVPA
>A0A7X6T6H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MKVTEIIEKGQGPLFTFELLPPLQGETIDSIYEAIEVLLPYKPAYINITNHQMETLYQER
EDGLLERISLRKRPGTLGLSAAIQYKYGIDVVPHIICGGVTKEQIDDLLSELVFLEIDNV
LVLRGDPPAGKRRFEATPGGHQYSDSLVRQIAEKEWADFSIGVAGYPEKHIEAPNLEHDI
AMLKGKIEAGAHYVVTQMFFENSHYFAFVERCRTAGIDVPIIPGIKPLQRRRDLELLPQT
FNIELPNRLVEAVERAKTPQEIRDAGRAFCIEQVSELIEAGVPGVHFYTQGRSQVIADVV
EATYPPYRERSTPTR
>A0A7X4H9J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|'Massilia aquatica' Lu et al. 2020|TrEMBL
MDTHNFSIEFFPPKTAEGAEKLRVVRAKLSELHPKYFSVTFGAGGTTQTGTLDTVREILA
AGEDAAPHLSCVGGTRESIRAILNEYKSHGIKRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQAKSPQDDLLAFERKVKAGANAAITQYFYNADAYFQFVE
QTRKLGIQVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLAGGAPGLHFYSMNQAAATTALWQRLV
>A0A806IP23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum ZJ316|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHADHPVYILGTIGGLAGDTDATVQR
ATPATIAASVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFVGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A7K9ZBA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dicrurus megarhynchus|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLRDKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYDADLRHLKEKFFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A842JK27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonibacter massiliensis|TrEMBL
MRSVSYLYEIAKAAGRQPVSFEIFPPKGDLTLEAAHEVAAQLADLVPDFVSVTYSAGGSG
NKQATADVAAMIHDDFDIPTVAHLTCLGATEESISHAIDDLKRKGIASVLALRGDRVPGA
APAEDAPFRFAKDLIMRLADEGFCVGAAAYPEGHIECTDFKASVAHLKQKQDAGACFFVT
QLFFDNAYYYRFRDAADAAGIDVPIACGVMPFLGKAQIQRMVFMCGASLPSPIIKLLAKY
EDDPASLRAAGIEYACAQLVDLQERGADGLHVYTMNQPDIARACTSALRASWSSAASGER
TGKAGDRADDGAAVGSAACGAAAGERTSKAADPSKADRSPGGASADAWASGGRA
>A0A150Z210|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. DOA1|TrEMBL
MTDVTTPATAEGHLRRPAISFEFFPPKTEEMERNLWDTINRLAPLDPKFVSVTYGAGGST
RERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPVGGIG
TPYCSHPDGYQSSAELVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKAKVDAGAT
RAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWFAAK
FDGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISHLLGIRAKSAQ
KAA
>A0A2E9KX60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MIFSKLMRSLKENKFTISGEIDPPKGADRTTIIEQAEYLKGHVIASNVTDNPLGIVIMNT
LVPCFIMQNEVEIEAVYQVTCRDRNRIAIQSDILGAAALGLKNVLALTGDHPRMGDHPES
KAVFDLDSVQLTKLLRIMIDEGTDMAGNKLKVAPKMHVGVGLSPGMRPLEPELIKFEKKI
RAGAEFSQTQVIYDSNILGELRDETKDCG
>A0A0L0NI71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elaphocordyceps ophioglossoides|TrEMBL
MDKITDKIAALPADAEYFSLEFFPPKTAMGFSNLRHRLKRMEQALRPLFVTVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRRLIDKALEDAKVLGIRNILALRGDPPRHDE
YRNSDDSEDDSSEDFASAIDLVRYIRRTHGDYFCIGVTAYPEGHADESHPLGQNLAHDLP
YLVGKVQAGADFIMTQLFFDIDAYDKFEETLREHRSGAFKTIPIIPGLMPIQSYQMIKRT
TKLSHARVPEVILSRLDAVKGDDEKVKMAGVDIVSELIEKVRTIKSRSPGRKGFHFYTLN
LEKAVAFIVERTGLIPDTSENDEAVIDDASSPPPMPQVNGNLSLRTRSHSRTSRRQSSVG
SDPHNRVIVGNRHPAHPEWEATGQEAGIPAESINSRANTLAISEGEGALGREATWDDFPN
GRFGDSRSPAYGEIDGYGVSLHMSVTQAVRLWGHPETRADINDIFVKHIQGQLTAIPWSE
EELMPESSTIKARLIDLNTKGWWTVASQPAVNGVPSSDSTFGWGPANGFVFQKSFVEFFI
PSSDWKTLSDKLNAPEVRDVVCFYAASAKGDFASSDSSGGANSTSPGASTNAVTWGVFPG
KEIVTPTIIEEVSFRAWSEEAFGIWSEWAKVYGRGSNSEKLLGGIKXGYWLVNIIHHDFV
EKDALWGLLMG
>A0A0L0NI71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolypocladium ophioglossoides (strain CBS 100239)|TrEMBL
MDKITDKIAALPADAEYFSLEFFPPKTAMGFSNLRHRLKRMEQALRPLFVTVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRRLIDKALEDAKVLGIRNILALRGDPPRHDE
YRNSDDSEDDSSEDFASAIDLVRYIRRTHGDYFCIGVTAYPEGHADESHPLGQNLAHDLP
YLVGKVQAGADFIMTQLFFDIDAYDKFEETLREHRSGAFKTIPIIPGLMPIQSYQMIKRT
TKLSHARVPEVILSRLDAVKGDDEKVKMAGVDIVSELIEKVRTIKSRSPGRKGFHFYTLN
LEKAVAFIVERTGLIPDTSENDEAVIDDASSPPPMPQVNGNLSLRTRSHSRTSRRQSSVG
SDPHNRVIVGNRHPAHPEWEATGQEAGIPAESINSRANTLAISEGEGALGREATWDDFPN
GRFGDSRSPAYGEIDGYGVSLHMSVTQAVRLWGHPETRADINDIFVKHIQGQLTAIPWSE
EELMPESSTIKARLIDLNTKGWWTVASQPAVNGVPSSDSTFGWGPANGFVFQKSFVEFFI
PSSDWKTLSDKLNAPEVRDVVCFYAASAKGDFASSDSSGGANSTSPGASTNAVTWGVFPG
KEIVTPTIIEEVSFRAWSEEAFGIWSEWAKVYGRGSNSEKLLGGIKXGYWLVNIIHHDFV
EKDALWGLLMG
>A0A428U9M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sp. AF-4|TrEMBL
MDRITDRIAALPADGSYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRREE
YRDPDDSEDDGGQDFNWAADLVKYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVEAGADFIMTQLFFDIKAYEHFENTLRDHPSGAFKTLPIIPGLMPIQSYQMIKRT
TKLSHAQIPEDILTRLNAVKGDDEKVKMVGVDIVSELVEKVKDIKSKTPGPKGFHFYTLN
LEKAVSFILERTNLIPEPPEDEEALVVDDAIPIPALQVNGSSNLRSGSHSRSRASRRHSS
VGSDPHNRVIVGDRPATHPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDF
PNGRFGDARSPAYGEIDGYGVSLHMSITQAVKFWGHPKTRQDINDLFVKHIQGELSAIPW
SEEELLAESSTIQPHLLRLNQKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEF
FIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVSSDKGGHVDGSSEAGPSTNAVTWGV
FPGKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSDSEKLLSGIKDEYWLVNLIHH
DFVEKDALWQVLSS
>A0A2S3ZT80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter glacialis|TrEMBL
MFASRLEIIPTQDIVPAVLERVPAGTTITVTCLPQHGVERTMDTASALAGHGFNVVPHLA
ARSISSRGQLAGILRACGTAGITELFVIGGDKGQSGGPFESSEDLMREIAQLSGKSMKMG
VAGYPEGHPSIADGQLMESLRIKQDLATHIVTQMCFSPSTIAEYMAVLRRDGVKLPVWAG
VAGAVPRTKLLRLATKIGVGSSLRFITGKGALGMTLLGGTSYQPEQFIADLADLPVPPAG
IHLYTFNSLDSLPEAGGLGPIHGTSDGAGAKGGVRSSAVPSP
>A0A519EBN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax sp|TrEMBL
MTTPVSIEFFPPNTPVGTDKLKTVVQELRAVDPLYFSVTYGAGGSTREKTLSTVADIASQ
GFEAAPHLSCVGSTRENIAEILSTYRDQNIRRVVALRGDLPSGTATAGEFRYAAELVRFI
RETQGADWDIEVAAYPEYHPQQRYAARDLQFFADKVRAGASGAITQFFYNPDAYFHFVDA
TRAMGIEVPIVPGIMPINNFARIAQFAQRDGIEIPRWVALKMEGYMDDAASVRAFGLDVV
TRLCERLIAGGVPGLHFYSLNQSALTLALCERLGLATKA
>A0A519ZMU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax sp|TrEMBL
MTTDHRRALPLSLEFFPPKTPEGVGKLAAVRQQLYPLKPEYCSVTYGAGGSTQDGTIQTV
KAILAEGVDAAPHFSCIGASKQGVRDQLAQFKAEGVKRLVALRGDLPSGYGGFGEFRYAS
ELVAFIREETGDAFRIEVAAYPEMHPQARSPAADLQAFVAKVKAGADVALTQYFFNADAY
FRFVDDVAKAGVDIPVVPGIMPIINSTQLMRFSDACGTEIPRWIRTRLESYGDDKASIQA
FGLDVVAELCARLQRGGVPALHFYTMNQATPVKALCERLGW
>B0NAG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium scindens (strain ATCC 35704 / DSM 5676 / VPI 13733 / 19)|TrEMBL
MGLERYEKRSIDMKIRDILKDNSPHVSFEVFPPKTDAGYEGVRAATEKIAALRPSFISVT
YGAGGGTSRNTVRIASQIKNDLGVTSLAHLTCVSSTKDEVHGVIGQLKEQGIENILALRG
DIPADGEFPLPNHYRYACELVEDIKSQGDFCIGAACYPEGHVEAAHKKDDIMNLKHKVDC
GVDFLTTQMFFDNNILYNFLYRIREKGITVPVLPGIMPVTSAKQMKRICDLSGTVLPERF
RAILDRFGEDPDAMKQAGIVYATDQIIDLIANGLNHIHIYSMNKPEVAEAIIGNLSTIIK
A
>F8Q7Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serpula lacrymans var. lacrymans (strain S7.3)|TrEMBL
MKLSEKIAAYNSPHPFYTFEFFPPRTDQGFENLITRISRLSSLNPIAISITWGAGGSTKE
RSLDLAGLTQAEYEIDTVLHLTCTNMKHGMVDDVLKAAKARGIQNILALRGDPPRGQEHW
IPIDPRFNHGIDLVTYIRSHQYFSSDFCIGVAAYPEGHPDGETDEDKELEFLKAKVDAGA
DFIVTQLFYDVDRFLHWVKRVREIGITVPIIPGIMPIQTYSSFLRLIKLCGVSVPSSIMS
DLESIQHDDQMVKDYGVQLAIDTIKRITTKGTVPGIHFCTLNLEKSVQLVLENLQWAGGS
PVTKNKLIAETPGSIIHPLPGSELIITPSSATSSAANALTTKQTADTEVGRGEVNYAATW
DDFPNGRFGDYKSPAFGDLGPWGAPVLSRTEVIDEWGSPKTEQDLTELFVRYLHSEITTT
PFSPSALSPESLRILSHLERLTQRGWWTVGSQPAVDCGNSTDPVFGWGPRGGYVFQKSFV
EFFADEEAVKEIVQKIEKEGQGVVHYFAGNMQGECRSNVPEDGRNAVTWGIFPGQEIVQT
TIIERESFLSWKDEAFSIWAEWASFYPPGSQERELLDVVMQKRWLVSIVHHDYRNPGGLW
TFLFGGNIAL
>A0A1T0ASI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus paracuniculus|TrEMBL
MSYAKEIDLLNQSVADLNGKINVSFEFFPPKNEKMENLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKTIQQETGIIAAPHLTGIDATPDELRQIAQDYWDNGIRHIVALRGDEP
AGYAKKPFYASDLVALLKEVADFEISVAAYPEVHPEAKSAQSDLLYLKQKIDAGASRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMSKMYQGL
DDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGVRP
>A0A0D6L504|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylostoma ceylanicum|TrEMBL
MSKSSAGSKIVEKREDRWVGHGNKYVPLHERINRRIKDKTPFFSLEFFPPKTANGVANFF
TRLDRFNEGGPLFVDITWHLGSDPANMNKETSSSSIAAGCLDYCRVDTMLHMTCAQYSKE
QTIKHLEQSKSVGLRNILALRGDLPNIDTDGIPIYKYRALDMIRWIREEFGDYFTIACSG
YPLGHPESPSYKADLLYLKSKCDAGAQFIVTQLFFEAEVFEQFVRDCREMGITVPIIPGI
MPIMGYDSIRRIATLSQLTIPESILSDLEPIKHDDDAVRKYGTIKAIEMCRRILSNGSAP
SIHLYTMNREGACREILQELGLWHKRPMRALPWEPHGSNHPLRSDWDDFPNGRWGNSSSP
AFGDLQDYYLFHLKAQTKKEDLLKMYGEELLSFDDVKKVFTNFISQGVNENGVKVTTLPW
NEQDVGVQAETKLINEQLLWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYL
ECFISKENAISLLEIVDDYYPRINYHIINHDGSFDHMNGEATTPIAVTWGVFPGAEIAQP
TVVDPLAFRAWKDEAYDTWIKNW
>A0A6L8N366|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5473|TrEMBL
MALGTASTRTDRARTVREVLATGQTSHSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVRATEQIASDTTLTPVAHLTAVNHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVRHPDGVTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVD
KCRAGADYAITQMFFRPADYLTLRDRVTAADCDTPIIPEIMPITSVGQLERFAQLSNAAV
PSELKERILAVKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYENLG
LHEQV
>A0A7U8LBY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae 35/02|TrEMBL
MQINYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTY
GANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASYDELRQIAKDYWDSGIRRIVALRGD
EPAGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHV
ITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYE
GLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A6I2JXN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium RIT702|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIARDYWDSGIRHIVALRGD
LPPGSGKPEMYGSDLVELLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMSAMFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAMGG
>A0A740VF41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar 6,7:c:1,5|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0M2S8R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. HK10|TrEMBL
MALGLPSVLPNPQPAIGELIRAGRPTFSFEFFPPKTPAGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGNPGGEWVKHPEGVRYAEDLVRVIRDAGDFSVGVAAFPYKHPRSPDVTSDTAHFVR
KCRAGAEFAVTQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQLGTIERSVQLSGAPF
PPALAERFARVADDPEAVRRLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWQHLR
ADARV
>T0T7N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HSISB1|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLIHPEKVSAIHKAYIEAGADVIQT
NTYAAKRHRLKGYGYEDKVKEINQAGVRIARQAAGKDIFVLGTVGALRGLKQCELSLDEI
IQETLEQVNYLLETNQIDGLLFETYYDEEEIIAVLKAVRPLTDLPIITNIALHEAGITEN
GKPLVEIFGKLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAIKGLKPVSRKFVTP
MVEEAELIKAVKQSETIVDKVKRQVTVIAEIDPPKTLDIEKFTEGVKALDDAGVSAITLA
DNSLAKTRICNVSIASLLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDILGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIKQLNKGKGYSGASIKKETTFTAAAAFNPNVKNLS
RCSRLIDKKIAAGADCFITQPIFNKEIIENLAELTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDDFLEKIEAVKDDKNKCQELALQESKALIDYALEFFNGIYLITPFMRYDLTV
ELVNYIHQKVEEKKQKYHKNGQLSPFFS
>A0A842I0G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasphingopyxis marina|TrEMBL
MNTPVIHPNWDLPPEVITDGFSIEMTAKDIEALEEAAPLMAPETPVAVTFLPGENLEMRI
EAAKAVRRLGFEPMPHFSARRFLSQHEFEEMARRVVAEADVKRVFVIAGDPPEAEGPFAD
TSAILATGLLEQVGIQAVGIGGHPDGHPNMTDEECWAVLKSKCADIESRGMASLIVTQFG
FDPDRFLDWLKELRERGIETPVRIGVPGPAGLKKLLRFAARCGVGASASVMKKYGVMSLT
NLLGTAGPDKMVDAFAAGLGPEHGKVRLHFYPFGGMKATMEWIDAYAARQKEVAA
>A0A1C7IAI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia pseudococcoides|TrEMBL
MKLSEAMRNKMLVSFELFPPKTDKGMENLPGTIEHLCKYRPEYISCTYGAGGTNVGKNMD
VCKMIQNAGTIPVTHFTCIGNTAEGIKEQLQNYLDNGVDHMLALRGDLPFGWTGTGGDFA
YATDLVAYVRKEFGDKIEIAVAGSPEGHITCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKRWLDAIRTAGITMPVDVGIMPILDQAATINMALSRNGCVMPRKLCEIISKNWIFPN
PFDKDPFDAAADEKKAAFKEAGIEYTISQIDEYRALGVNGIHLYALNKWKDVSEIIDRCG
LRTLV
>A0A1W9N735|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaeta sp. LUC14_002_19_P3|TrEMBL
MRIKDLLKTGKTAISFEFFPPKTAGGWEKLFGTIAGLVPLNPAFVSVTYGAGGSTREKTH
ELVARLQQEAQLSVCAHLTCVGHSRGQIREILNQYAAIGVNNILALRGDIPQNTIEGEFR
YAADLVRFIRSEQPDMSIGVAGFPEGHPESRSRLDEIDRLKEKTDAGADYIITQLFFDNR
DYFDFVSRCELADIKLPIIAGIMPVTSTANITRMAELAPRTRFPASLLRAVNRAAGKEGV
EHAGIHWAAEQVRGLLDKDVPGIHLYTLNHSRAVLGILDALGLATPA
>B3QMQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobaculum parvum (strain DSM 263 / NCIMB 8327)|TrEMBL
MLVKEILDAKTEPVFSLEFFPPKKQDDWDKLFATISNLSPLDPSYVSVTYGAGGSTRERT
HNLVTKIQQETGLTVVSHLTCIGAEKSEIESVLQNYREHGITNVLALRGDKPADIPTLAE
AIKDFPHAIDLVKFIKANFPEMGIGVAGFPEGHPETPNRMKELEYLKEKIDAGADYIVTQ
LFFDNRDYFDYVERCELAGITVPIIPGIMPIMTKKGMIRMGELALGSRIPSKLLRKVLEA
SDDKEVAEIGVEWATNQVQELLDHKVKGIHFYTLNLSEATLKIFRNLKRG
>A0A257JTB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium PA3|TrEMBL
DGYVNATEVTAAARRIADFDVSVSFYPEKHPESPSLQHDIDVLKAKIDAGATRGISQFFC
DADVYLRFRDAAVKAGITIPLLPGIMPVGNVAGYTRMATSTGTSIPAWFAEAFDGLDQSP
EVRDMVAASVAADLCLKLQAEGVDRFHFYTLNRAELALATCRRLGLKTPVTEKDAA
>A0A1D3RMY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|methanotrophic endosymbiont of Bathymodiolus azoricus|TrEMBL
MMTKKNKADLFSFEFYPPKTEEGAVNLEKVHQELAQLNPDFFSVTFGAGGSTRDKTYDTV
VKIQKNGVSAAPHLSCVASTKENILEILQNYRQHGVSKIVALRGDLPSGMMSAGEFRYAN
ELVEFIRKETGDHFQIHVAGYPEIHPQASCAQTDFDNFKRKVDAGANAVITQYFYNAEAY
FYFLDKCEKSGIDIPIVPGIMPITNYSQLFRFSDMCGADIPRWMRKTLEGFGDDRESIVA
FGEDVVSKLCQELLDNGAPGLHFYTMNQAKPTLAVWNNLKF
>A0A454W880|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC02707|TrEMBL
MALGTASTRTDRARTVRDILAAGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVELIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEIMPVTSVKMLERLPKLSNASF
PAELKERILAAKDDPAAVRSIGIDFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A1F8TDV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RIFCSPLOWO2_02_FULL_71_16|TrEMBL
MRIADAYRTGKPVFSFEFFPPKSPEAVLRLRSTITTLRRHRPDFVSVTYGAGGSTRDLTI
DVVTRIKRDTGVEAMAHLTCVGHTAEELAAVLDRLEAAGVENVIALRGDPPRGQKTFKQP
EGGFGHGSELAAFIQSRWSFCVAAACYPEKHPESHDLDEDVRYAKLKQDIGVEVLISNLF
FDPADYFRFVERARAAGVTVPIVPGVMPITNAGQLAPTGMFARTGASIPDALRSRVAAAN
GDERALTAVGVEWAVRQCRALLEGGAPGIHFYTLNRSHSAYAVCESLRAALPATVGAR
>A0A0C4WU03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azotobacter chroococcum NCIMB 8003|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMTVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRSLLNTYQDAGIRRIVALRGDLPSGMGMASGELRHASDL
VEFIRAETGEHFHIEVAAYPEMHPQARHFEDDLRHFATKMQAGANSAITQYFFNADSYFH
FVERVRKLGVEQPIVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFG
EQVVTQMCEKLLDGGAPGLHFYTLNQAEPSLAIWNNLGLPR
>A0A1D8AWN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacunisphaera limnophila|TrEMBL
MLPDTSISTLFSLQRPLRSLEFFPPKDEAGVIALRETALTLKRIAPDFVSVTYGAGGSTR
ERTAQVSRLLREEIGFTVMPHLTCVGHTRDELHAVADQLHAGGYRNIMTLRGDPPKGQTE
FVPYQDGLRYGSDLVALLMARHPDFCLGVGGYPEKHPEAPSLEVDLDNLKHKVDAGAAFI
TTQLFFDNAVYYRFVDRCRARGITIPIVPGIMPVLSLKQIKRFTEMCGATLPATLIKRLE
AAHEVPEILESVGNEWAVSQIRDLLAHGAPGYHLYIMNRAKSALALAAGLAA
>A0A2S5ZAQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter maroccanus|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYREHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>E9TD17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli MS 117-3|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A662F5T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon|TrEMBL
MKRVTELIAKGFTISVELVPPRNGIPLNSVLEQFKEIKQGVDFVSVTMGASGSLRGGTFP
LSYFIQARFGIPVVTHFVCREHTRYQIENMLMDLHHFGIRNILALRGDPPAGQKDSGWSG
DYPRAYMLVEQIQRMNQGIYLPRIGFEEKPREGLKTEFCILVAGHPEYPLDKEISNMRLK
QDSGAMAAITQMAFSPADYRAYIKAIRAANISIPIIAGVRPLKSLNQGLSCESFFKIKLP
QKLKEGFKKARDEYKFGLDYTAKLIKEIKSCGYAGVHLFCLNDFKLVKDLIVRINI
>A0A6J6XN30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVVTSTTVQGISPRAPGAVATMSIFRSRQRSGTVDEQPIAQGILDRVAHAHLELIPTPKA
HLQFPELPEASTVSVTCSPAKDIQATLDMAAQLQDLGHTVIPHLAARMVEGPEQVAAIAQ
WLNAHDVRDVFVIGGDAPDPHGPYLDAGALIEALLNSNANLANVGFGGYPEGHATIPLNK
LADAVASKQQLLDTAGVGGWVSTQMCFDTKAVSKWIQHSRSQGLHLPIHLGIPGVIDTTK
LLTMGAKLGIGASLRYLRKNRAVVSKLAAPGGYDPMEMLSPLAREFESLDISALHVFTFN
QVANTAAWRRAVIGVAAHAH
>A0A6J6TEL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MWAALEALEFIAPEFISVTYGAGGSTRNRTIGVTEEVRQRTKIPTVAHLTCVGSSRQEII
SILHMYRAAGIRGVLALRGDPVGGPRAPWTPMPDGFTHADELVQLIHEFGGFDIGVAAFP
DGHPSSNGDAKKDIDVLLRKEHLGATFATTQFFFDVSKWEQLVYALQARGSTMPIIPGIL
PITNVKQLQRMAELGGTDIPPAVSSAFSAVEDDVDAVHALGIELASTLCEDLLRAGAPSL
HFYTMNSATATKEIYRNLNNAH
>A0A6J6G4R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARIADLLASGPTFSFEFFPPKNEAGWLSLGRTIAELEHLGPHYVSVTYGAGGSTRTRTA
DLVSWVKRQTPISPMAHLTCQGHTRAEIRDILIDYRAEGVQNLLALGGDPPADGSEHAVS
EYRFSSELVDDIRAFGGFSIGVAAHPEGHPRSPDLVSDRAHLARKLADADFAITQFFFEI
DHYLSMMDDLASHGVDKPVIPGIMPVTNLAQVSRMAHMSGAEVPRWLVEKVSKAGDDPEE
AVRIGVDIATELCARLLEVGAPGLHFYTLNRSGPTRDLWRQLGLDAPPDAG
>A0A6J6NCJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSKLRDLLTQTKDVVYTAEFPVIDGGGMDQVKKNVERLAPWFAAVNATDNTAAHAHASNV
SVAIAMKQHGLEPIMQIVCRDKNRLAIQADMAGANLHGIENIALLTGDDVTAGDEPETRR
VFDLDGPQAINVASILNAGTYLSGRKLNPAPNFFICAVENPFAPPHDYRIERALKKHRAG
AQMLQLQIGYHPDRLEKFCAGVAATVPELALIPSVVLVKSSKPLNFMNDKVPGISVPQDV
IDRVAQSSDQAEAAYQLALEQCQHALALPGVRGLHITDFRHDETLERLMHDLGRTPNQYT
>A0A6J7J512|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRRPFSFDTPNGKPIFSLEFFPPKDEKGEANLWVELAELNSLQPEFVSVTYGAGGSTRER
TVRITSEITARTGLRTVAHLTCIGSSKNELSEILDQYWQAGIRDILALRGDPPTGPQSEW
IPTAGGFSHSDELVSLAAAANFNVGVAAFPDCHPASNGDHLKDISVLLEKERRGAQFATT
QFFFSTDKYYNLVNELKEQGSNLPIFAGILPITQVKQLNRMAQLGGTPIPANIVQKFSRI
EDDPEKVKALGIEIAVNLCEELIAMGAPGLHFYTMNNAYATKEIVKRIGLR
>A0A7C1KHK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmata sp|TrEMBL
MHIRDIFAQHHPTFSFEFFPPKTEEGSEALFRTIAALQELEPSFVSVTYGAGGSTRDRTH
DLVVRIQKETRLTAVSHLTCVCHSREEIAAILGRYARAGVLNILALRGDPPRSMPHYDRS
QDAFRYAAELVRFIREFPEPPDPRGFGIGVAGFPEGHPECPNRLKEMDYLKRKVDAGADY
ICTQLFFDNRDFYDFRERCELAGIRVPIIAGIMPITSRKNLETMAELAAGARFPAKLLRA
VGRCSDDEDVARVGISWATEQCADLLHNQVRGIHFYTLNRSDATVQIYRNLGVKSSRALR
QAI
>A0A6J6NIB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MAGHFLSRLNDGPPIVADGGMGALIAAAVPRLRNPVEANLRSPDAVVSLHASFINAGAEL
IETNTFAANRHKLASYYLDDEFELINSTAVKLARDAREMTGRDVFIGAAIGPVGENIPSE
QRKSIFAEQADILAGRGADLFMVETFYDLAELEDAVTAIKEVSNLPIVALLTFDEGGVTL
AGVTAKEAADRLSALDIAAIGANHGAGLLAALTALEQMKAEGRALAALPNIGLASLSGGR
VVYPHATPDYFVEFAAHARDLGARIIGGCCGTTPTEIAAIRTAIDEARPARSELTLAERD
IVVALGEEARETRLATALREKQFVVSIQLDPPLGGSNRGLLETSTAIADSGLVPFVDVND
NATARAGMSSLMVSGAIERATSLETIPHLTTRDMTILGLESMLLGAHAEGVRNVLAITGD
PPEIGDYPGSQGVYEIDAIGLTRLISGLNRGEDFNGRPIDAPTSFFVGVAVNPTADDLEA
EAERFRQKVEAGAKFAMTQIVFDLDHIDRFGELLGGWPIPVLAGIFPVTTFRLALRLHNE
VPGILVPQELQDALDAAGPNASEVGFAHARELLAACRGRVDGVYIVAPYRRPTAVLDLLS
SL
>A0A838LRQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MNTEISFEFFPPHSAEGLAKLRSVRARLATLGPTFFSVTYGAGGSTRERTFDIIMEIAAE
GLAAAPHLSCVGSTRAGIREILDSYRAHGIRRLVALRGDLPSGTADAGEFSYANELVEFI
RAETGDTFHIEVAAYPEWHPQAKTPRDDLLAFKRKVDAGASAAITQFFYNADAYAHFVDE
AFALGITIPIVPGIMPIGSFTKLARFADSCGAEIPRWMRKKFESFGDDSDSIRAFGLDVV
TELCQRLLDLGAPGLHFYTLNQATLSSEIVRRLGLNKPV
>A0A6J6D9H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MDFSLLQASRATSKPTFSVEFFPPKDEAGEQRLWDSLSLLAENDPDFVSVTYGAGGSTRD
RTIRITAEITARTSIPTVAHLTCVGATRSEVDAILTRYKESGIATILALRGDPPGGPSAE
WIQTPNGFNHADQLVELAVERGFTVGVAAFPDGHPASGGETARDVDVLVRKFELGASFAT
TQFFFDVSKYQELRDRLSAKGVDRPLIAGILPITNFKQLIRMAELGGTPLPKVVIDRISR
FQDDPDSLRKEGIEIASELASDLIGVGAPGLHFYTMNSAHSTMEITARIGLR
>A0A6J5ZH94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRSGVTYSFEFFPPKDVEGEERLWSAMSQLENISPDFISVTYGAGGSTRDRTIRITSEIT
ARTHIPTVAHLTCVGSTRSELVEILGKYRDAGITSILALRGDPTGGPRAPWVPTQGGLNH
ADELVTMAAEFGGFTIGVAAFPDGHPSSHGDIDKDIEVLLEKERRGATFATTQFFFEVDK
WKALVDKLAAKGSSLPIIAGILPVTNVKQLNRMAELGGTPIPASIAERFAAVENNPEDVS
KLGVEIATNLCHQLLESGAPGLHFYTMNSSTATREIYSQIKDDR
>A0A7C6RHD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MKPEISIEFFPPTTAEGADKLRATRDRLAALKPSFFSVTYGAGGSTRERTFATVKEIAAA
GFEAAPHLSCIGSTRDSIREILQEYADAGIRRIVALRGDLPSGAGAAGEFRYANELVEFI
RAETGERFRIEVAAYPEWHPQAKSPRDDLAAFKRKVDAGANSAITQYFYNLDAYLYFVDA
VRKIGIDVPIVPGIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDSDAIRAFGLDVV
TRLCEKLLAEGAPGLHFYSCLLYTL
>A0A6J6EG56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MAKNSQRNGTLLTMGTKLRATSFSLEFFPPKDEAGEQRLWLALSELAPLAPDFVSVTYGA
GGSTRDRTIRVTSEITKRTQIPTVAHLTCVGSSKNELIQILNQFKYSGIESILALRGDPV
GGPTAKWEPTADGLNYAQELVEIAVEMGFKVGVGAYPDGHPASNHDLAKDITVLLAKERA
GASFATTQFFFEIDKWQGIVDKLAAAKSQLPVIAGILPITNVKQLNRMAQLSGMQIPADI
AEKFTKLADDVEGTRKLGVEIATNLGTELLRRGAPGIHFYTMNSAQSTIEIAQNLGLIQN
A
>A0A6J6JAE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MNKQVRVSFEVYPPRDQNSGESLESSIIELAKMDPTFISVTFGAGGSSTKNSLEVLKYIL
QNTQAAALAHLTCVGHSFLETKALVNQFMDEGISDFLALRGDPQPGMPVEPKGELKTSSE
LVQLISQVHKDRGNSRSALNVAVATFPNGHPDSDSIAQDIQALLAKQNAGADYAITQLFF
FASDYVAFVKLAREAGVTIPILPGIMPVTSMQRLNRVIELTGEKYPEALAKQLSVTSKEE
AKQAGIDWAANLVAELVEQGAPGVHLYAFNQHESVTQVLQRAGIR
>A0A2T8HJJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium corticibacter|TrEMBL
MKIIDHITNAQGKTLFSFELLPPAKGQGIQNIFQTMDELMEFKPPFIDVTYHREDYLYKQ
HANGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLDFLGIDN
VLVLRGDARKGDADFIPTEGGHAYATDLLQQVKDMNEGKYLHEDITTSSKTDFCIGVAGY
PEKHFEAPNAQTDFKWLKKKVDMGAEFIVTQMFFNVERYKEFVTKCREHDIHVPIIPGLK
PLTTKKQLITLPRIFHLDIPEELSEAVEGCKNNAEVRQVGEEWLVNQCRELIAFGAPVLH
FYTMSNPGPTKNIVQQLA
>A0A6J6F7I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSNDLRDTSFSLEFFPPKDLAGEERLWQVLAQLQPLHPDFVSVTYGAGGSTRDRTIRVTT
EITARTAIPTVAHLTCVGSTKFELIEILNQYKNSGITSILALRGDPQGGPTAAWQSIADG
LDHADQLVEMAMKLGGLEVGVAAFPDGHPASNFDLEKDIEVLLRKEELGATFATTQFFFE
FEKWQKIVDRLSQKGSKLPVIAGILPITNLKQLSRMVELSGIQIPAQILAQFDNAADNPQ
EVKKIGIEIASELGAKLLAANVPGLHFYTMNTAESTIEIAKNLGLVKL
>A0A829SRH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis str. 3783N1-8|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYQDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A6J1MM19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bicyclus anynana|TrEMBL
MSDRITEIFNNDGRKEKFTYSLEITPGVKEEELENLNLEPTFFSITWHAYAHGCKDFDIE
PLKLAKYLRSKKKNVLLHISCANVKKDYIDKLLVLLKEMGICNLFIILGEKFDSSHSDFE
GSKAMITYIRQRTGDYFCIGVAGFPGREGNILQLKEKTDSGADFILTQAFFECDELIQFV
TGCKEAGINVPVIPGVFPFETQTELEGFIRLCKVHITEDIIRNLNNQSGIKIVVGLVNQI
ILRLDIWHFHFFTLNKMSRITTLINLLSK
>A0A240E4Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter puyangensis|TrEMBL
MSKHIPISFEFFPPKTDVGAEKLKVVHQQLQLLQPEFFSITYGAGGSTRERTLAAIEEFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHAGDHFQIEVAAYPEMHPQADSFDQDIQRFIEKVQAGANAAITQFFFNPDAYFYFI
DRLQKAGITIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSKSIQAFGHE
VVLKLCERLIAGGAPSLHFYSMNHTEPTRQLVVDLGLA
>A0A212A953|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haematobacter genomosp. 1|TrEMBL
MTTPRISFEFFPPQSLEASFRLWETVQALAPLNPAFVSVTYGAGGTTRKLTHEAVTTIHR
NYGLNVAAHLTCVDATREETLEIARAYAEAGVKEIVALRGDPPKGASGFTPHPEGFASSV
ELVEALAATGDFRLHVGAYPEPHPESPDTPSDVAWLRRKVAAGASSAITQFFFSPDIYFR
FRDAAVAAGVDVPIIPGIMPVNSWKGVRGFAARCGASVPASLDARFTAAVDAGREAAFAV
EQCTELCEALIAGGVEDLHFYTLNRPQLTQQVCANLGILPAAESAA
>Q9EYI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces nogalater|TrEMBL
MNPALLDDFSLEMTGKDVPRLEEARDGIPPGTRINITFLAGEDTATRLTAARAVKRLGFV
PVPHISARRLPSRPALEEFLAGLAAHGTAENVFVVGGDPARPEGPYADALAVLRTGLLRR
HGVRHVGIAGYPEGHPGITDRALWSALTDKAAAIDADRFGGDVITQFGFDADPVLAWLEA
LRARGVRLPVRVGVPGPAGVRRLLGYATRFGVGTSASVARKYGFSLTNLMGTTGPDRFLH
ALADRYDPGRHGVVKVHFYTFGGLRATAEWVDGFRRQHTPAPAP
>S7VM03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclobacterium qasimii M12-11B|TrEMBL
MKVTEYLKNTDKTHFSFEILPPLKGQSLTNLLEGITPLMEFNPPFIDVTYHREEYMYKKH
ANGLLEKISTRKRPGTVGICAAIMNKFKVDAVPHLLCGGFSKEETENALIDLYFIGVENV
LALRGDAPKLEPNFVANKDGHQFASELVAQITGMNQGKYLHDETEIGFQTDFCIGVAGYP
EKHFEAPSLNFDLKKLKAKIDAGATYIVTQMFFDNQKYFDFVEKVRAAGINVPIIPGLKP
ITTLSQMVNLPKMFFLDLPDDLMVELEKCKNNADVKEVGIEWAIQQSKELVKYGVPTLHY
YTMSKADTTYKVAKEVF
>A0A1Q8KMM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. Ae707_Ps1|TrEMBL
MVTSVTTTSASTVTERISVDRPFFAVEFFPPKDDQGEADLWRAIRRLEVLDPAYVSVTYG
AGGSSRDRTVRTVERIASDTTLCSMAHLTAVSHSTEELRHVIGSLAAAGVRNIMALRGDP
PGDPLGEWVKHPEGLEYADELVSLIKRSGPFCVGVAAFPYGHPRSADVESDTEKLVGKFR
AGAEFAVTQLFLEPDGFLRLRDRVAAAGFDQPIIPGIMPLTSEKTFHKGPELSGSPLPEA
LVERLSKYSGDAKAFREAGMEVTGELCERLIAEGVSGIHFYSLNRSTATTELVERLGLAA
QPAGADRAGSEAVLPV
>A0A2C5XM45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceratocystis fimbriata CBS 114723|TrEMBL
MHISDKIANAKRAGEPSFSFEYFPPKTAQGVQNLYDRIERMNELGPQFIDITWGAGGRIA
ELTCDMVQQAQTIYGIETCMHLTCTDMGNAKIDDALSGAYKAGCSNILALRGDPPREKEK
WEPTDDQFHYAQDLVSYIRQKYGNHFCIGVAGYPEGCDDNKDEDSLLDHLKQKVDAGASF
IVTQMFYDVDNFLRWVRRVREVGITVPILPGIMPIATYASFLRRAKHMNCTIPADWLDVI
EPVKNDDVAVRERGRKLVTDMCHKILASGLIHHLHFYTMNLAQSTRMIIEELNWLPSAER
PIKQALPWKQSLGLGRRDEDVRPIFWRNRNKSYILRTQDWDEFPNGRWGDSRSPAFGELD
AYGIGLAGTSEQNRAKYGTPESVRDIAELFVRYLKKDLESLPWSESALTGETSIISDKLI
DLNSRGLITINSQPAVSGVKSSDPVHGWGPKGGYVYQKAYLELLVHPDVYPELIKRIESN
PDMTYYGVTKTGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGED
WARCYEAGSPSHQLIENIINNWHLINIVNNDFHQNDSIFALFSGLVVPGVNDIVPSSAPH
SPTLAQDASSVKGPTEIAVNGTQ
>A0A1Y5KI45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. MY03|TrEMBL
MSGALAAKLSLREALAERILTGDGAIGTYLYQMGFPVGVSYEEFNVLKPDVIENVHRQYY
EAGARVIETNTFSANSVKLSKYGLESEMEAINRAGVRIARAAVGPDAYVVGAIGSIRDGK
LKNLRTSLVADAYEQQMKALLEEGVDGLLLETFYDLAEMKLAMSIARKLTDIAVICQFAV
EDVGRTLDGVALSDAFSELKEMGADVIGFNCRSGPNGIMRAIDSIGERPEDVPMSVYPNA
GIPDYVDGKYAYSAGPEYFAESAKRFADRGARIIGGCCGTTPEHVAAMAAALAGYVPAAP
GANQAESASISVTETLAGGTGEGDRDETPNIVDLVKQRHTVIVELDPPRDLDISKFMTGA
AALKEIKADAITMADNSLAVTRMSNLALAALLKERVDIRPLVHIACRDRNLIGTQSHMMG
LDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNDGIAFSGKPLKQRAKF
VVGAAFNPNVKHLDKAVQRLERKIASGADYIMTQPVYDPELIVRIAESTKHLDVPVFIGI
MPLANGRNAEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAEGVRIAKELLDAALPHFNGIY
LITPFMFYDMAVQLTEYVWQNTKQLS
>A0A7Y0ZIM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. WS 5010|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCETLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A0R2MDE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus xiangfangensis|TrEMBL
MDLRQALKQRVLVADGAMGTLLYGNYGISSAFENLNLTHPDTILRVHQAYISAGADIIQT
NTYAANRLKLARYDLQDQVTAINQAAVQIAHSARQHADHPVYILGTIGGLAGDTDQEIQR
ATPAAIASSLTEQLDALLATNQLDGILLETYYALPELLAALRLVKAKTDLPVITNVSMLA
PGVLRDGTTFAAAIRQLAKAGADVVGTNCRLGPYYLAQSFEHLAIPENVQLAVYPNSGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTAATVRGLTSRTIIHHRT
PTHQPLATPLAPAKGQHPFLAKVATAKTVLVEMDPPRNFDTTKFFKGAQRLKAAGVDGIT
LSDNSLAEVRIANVTIAAQLKLNYSITPVVHLTTRDHNLIGLQSEIMGLHSLGIDDVLAV
TGDPAKLGDFPGATSVSDVRSVELIKLIKQFNSGIGPTGKSLKQASDFRVAGAFNPNAYR
TDVSVKSIERKLAYGCDYIITQPVFDLANIYAMADALKASNIHVPVFVGIMPLVSKRNAE
FLHHEVHGIRLPKTVRDRMAQAELDGNEREVGLQIAKELIDGVCEVFNGVHIVIPFNRFK
TAIELVNYVQQKNLTATH
>A0A8D5WHH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium SO-S41|TrEMBL
MPLNVSFEFFPPKNDAAEQTLWQSIGRLAPLNPSFVSVTYGAGGSTRERTHATVKRIVDE
TALKPAAHLTCVGATKAEIDGVIRDYWDAGVRHIVALRGDMPDMGAAYQATAGGYDSTPA
LIEGIKAIGDFEVSVSCYPEKHPDTPNLDADIDLLKKKIDAGATRAITQFAFDTDSHIRF
LERARRLGVKIPVVPGIMPTTNFKGIVRMAGRCGASVPHWLHERFEGLDEDLETRKLIAA
TVAAEQVERLTAIGFDNIHFYTLNQADLTYAICRILGIKPQGAKLDAAA
>A0A440N684|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVVREFADMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVDAMKSAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A6B2S7F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID10853|TrEMBL
MASGTSSTRTDHARTVRDLLATGRTLYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSSRAGTVRATEQIASDTTLTPVAHLTAVNHSVAQLRNIIGQYADAGIRNILAVR
GDPPGDPMGEWVKHPEGVMYAADLVRLIKESGDFCVGVAAFPEMHPRSDNWESDIRHFTD
KCRAGADYAITQMFFDPEDYLRMRERVVAAGCDTPVIPEVMPITNVRQLDRFAQLSNARF
PSGLKERIHAVKDDPAAVRSIGIEFATEFCAKLLSEDVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A530KKL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A529N948|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
IMQIACRDKNRIAIQGDVLGGAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETC
RIMRDNGKFLSGRKLTTPPQIFLGAAVNP
>A0A2E7T998|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MTKLSQKLTGSDFLITSELTPPKGTDLKGLLDKAESLRDQVTAFNLTESHAARMSMDPVA
VAHLMLDRDCEPIVQMTSRDKNRIAIQASMLGAAALGVGNIVFMGGDSPKNGDHPDAKPV
FDLYASQLLEAALSLRSGKDLAGNELHGTPQLTVGAVFNPGAGDVSAEIDNIRRKEDGGA
EFFQTQAIFDVPAFESFIEKACPKKPVLAGVIPIKSVKMALYMNEKVPGIDIPADIIKKI
EAAGDDKEQIAAISVEVAAHTIRELRPIARGIHIMAIGWEHYIPSIINKSEA
>A0A4R5NQP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus buchneri DSM 20057|TrEMBL
MSLTALFKQKTVFSLEVFPPKKDSPTDAILPTLKRLQSLQPDFISVTLGAGGTNHCDGTV
AVADLIQNQLNIPAVSHVPGLYQSKDQVLALLDRLDQIHVKNILALRGDRIPGKEPVGDF
NHANELVKFVHEQRPDFSIASACYPNCHTEAADFVDDISHLKEKVAAGADHLISQLFFDN
QAFYDFKEKTEIAGINVPIEAGIMPCTNKNQIERITQISGVPIPKKFAAIMDRYQDSKEA
MLDAGIAFAVDQIIDLVSQGVDGIHLYTMNKSKIAKRIWEETESVFAASNLAKQKANQN
>A0A134BW88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella parvula|TrEMBL
MMTLREKHQQRQFTITVELDPPKSSSAEKTFEQAARLKGKVDAINIADSPMSKMRMSPIS
LSYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQS
VFEVDCMGLLNIAKTLNAGKDLAGNDLDAPTNFYIGATGNPGAPDLEIERQKLAAKIQNG
AHFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILD
RMEKGGKEAGTEIAIETLEQIKKMAAGVHIMPLNDIDTTLYIIDHL
>A0A531AKU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
TELNPPDSADPEDVYNRAKIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQI
ACRDRNRIAIQGDVLGGAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMR
DNGKFLSGRKLTTPPQLFLGAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFR
TYMQQVRDLGFTEKCFILCGVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEG
KQLCIDIINEVKEIPGVCGVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAD
RLDHILHDEITETQVDMVKTAH
>A0A528F9A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIARQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLE
>A0A2E8MH26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MSNAADVKVSGPSYKSSSDLERILAAGYFAVTGEIGPPKNWNAEVIREKAKLLKDCVDGA
NITDNQTAIVRMSSIAAAIIVKQEGLEPVIQMTCRDRNRLAMQSDLLGAAAHGINNVLCL
SGDHQSFGNHPGAKNVHDIDSLQLVQMVKGLREGHFQCEEEIKGGGPGYFIGAAANPFAD
PLEWRPFRLAKKAAAGADFIQTQLVYDIPQFREYMKKVVDLGIHERTAILAGVGPLKSTA
MARYMRDRVPGMRVPDECIDRMTGAVAGIDQNDKKARGEAWRAEGLKLCIEQIQEIRDIE
GVAGVHITAIEWEAAIRPLVEGAGLVPRPCVESA
>A0A530YRF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A239RIC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotellaceae bacterium KH2P17|TrEMBL
MNVAELLNRNKDQRNFSFELLPPLKGSGTDKLFATIEKLKEFGPLYINITTHHSEYVYRQ
LDNGQFERLRIRRRPGTIAIAAAIQQRYDLPVIPHVICSGTTVEQTEYELLDLQFLGISN
LLLLRGDKARDDRSFTPTEGGHAHTTDLIAQVNRFNEGFFADGSPIKCPGTPFGYGVACY
PEKHEEAPNLEMDMKYLRQKQDMGAQYAVTQLFYDNRKYFSFVDKARQMGITIPIIPGIK
PLAKLSQLTTVPKTFHCDFPQELASEIVKCTTDEQARQLGIEWTTHQCRELYAHGVNNIH
FYTVSAVDSVREVVRRLQ
>A0A527I2S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQ
>A0A530YT97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
SAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAAGSAAA
>A0A3M4CAM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. atropurpurea|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDGKDDLRSLLAQYREAGIKRIVALRGDLPSGMGMASGELRHANDL
VTFIREETGNHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A528ZVR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAINPFAPPYDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRAYMQKVRDLGYDEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEVTETQVDMVK
TAH
>R7D5P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus obeum CAG:39|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSVGMVRFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A3D3L0R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEKIANYKTQGKTFYSFEFFPPKTDFGLDNLYSRIDRMASLQPAYIDITWGAGGSTS
NKTLEMCKTIQKYFGLEVMMHLTCTNMQVSSIKKVLIEAEKNDLSNILALRGDPPEGSSS
WEQHEDGFRHGIDLVRYIRKEFGDHFFLGVGGYPDGHQEQSDLDADISFLKEKVEAGADI
VVTQLFYDVDKFLFFRDKCIKAGIKVPIIPGIMPIHNYARFLKFTQFCQVSVPDSVTEQL
ELIKYDDSSVINYGIDQASGMCQKLIKNGVPGLHFYTLNLENSVSAILKSLGLVSSQGII
KELPWRQSTSDDRKTSEDVRPIYWSNRPVSYLTRTEIWDDFPNGRWGNIESPTFGELNQY
HAIRAGSKSDKIRAKRKKIWGEPKNIKDITDVFVSFCKGKINSLPWCEMPLAQESKQISG
DLLKLNEMGYFTINSQPKINGFPSEDAEVGWGGPGGRIYQKAYLEFFTSKDKLDRLLKSI
GSKENISYEAINISSDLITNLPENNAMAVTWGVFPNKEIIQPTIVDTRSFLIWKDEAFSL
WMNDWASIYEAKSRSYKLLKEIYDTYYLVNIVDNDYVDGNLMQQMLIF
>A0A8H2P1G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSEERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKEDLRSLLAQYKEAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIRRETGDHFHLEVAAYPEMHPQARNFEDDLANFVRKVKAGSDSAITQYFFNADSYFY
FVERVQQMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVNSIQSFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A8D0AFX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sander lucioperca|TrEMBL
MVNQVQRGDGSWQSCKSDSSGASNSSESSKESSRSSTPVLDVDRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGTGGPLFIDITWHPAGDPGSDKETSSLMIASTAV
NYCGLESILHLTCCNQTKEKISGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATD
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNY
GIKQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LKMWGDELMSEESVYEVFTCYITAQPNRSGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIAGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVN
YHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWKVIDDMFELLDATPEPLDATPEPL
DATPEPLDATPEPLNEGAASE
>A0A0W1RWF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Guyparkeria sp. XI15|TrEMBL
MSIPVSCEFFPPKSDEGEAKLREVYQTLAREIRPEYFSVTFGAGGSTQTRTFETVREIQR
DSGIPAAPHLSCIGSSREGIAAILDDYREQDIRRIVALRGDLPSGMQDPGDFRYANELVA
FIREYSGDWFHVEVAAYPEIHPQAPDAETDLANFKRKVEAGADAAITQYFYSIEAYKRFL
DDCERLNIDVPIVPGVMPITNYQQLARFSDMCGADIPRWLRKRLEGFGDDLEGLRAFGHD
VVAELCRQLVDAGAPGIHFYAMNRSGPVIRLCEDAGLIDD
>A0A3D3P864|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriaceae bacterium|TrEMBL
MFLNKIKSGKSGILLYGITPPKSETSPERIAEIAEKTLARLFPLDIDALVVYDVQDESSR
TSEERPFPFMHALDPFKFASEHLQALTIPKIIYRPAGKFTREELSDWLENIHRSNFYPVF
VGMPIPDYPVKTSLKEAYQIWRKHENTSVIGAITIPERHAVLKDEDVRILDKISCGVSYF
ISQCIFNVEYAMQVIEDLSRSCKRDNIKFPTLIFTLTACGSVKTLHFMEWLGIHVPDELK
EDLRNSENILDKSVGICLDIAEKLTTFCIERSIPFGFNIESVAIRKEEIEASIYMVNKVS
EMLNERGIRKRAGSMEQNA
>A0A3R6L7G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. AM23-5|TrEMBL
MNIAEFLHQKGDKRGFSFEVLPPLKGNGTAALFRTIDSLKDFDPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHVICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHTNATDLLKQVNQFNDGFFFDGTPIKHPGEKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGADYAITQLFYDNEKFYAFIEKARQMGITIPIVPALK
PFAKLSQLTMVPKTFHCDIPEALAQEVLKCKSDEDAKALGIEWTTAQVKDLFDHGYNHIH
FFTVSAVDSVKQIAKILF
>A0A0P8ZPB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQERRYSFEFFPTKTDAGQEKLLATARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGNHFHIEVAAYPEMHPQARNFEEDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWKNLKLPR
>S3ZMX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides stercoris CC31F|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEKNGYHHAVELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTNEILKCKTDAEAQQVGIEWCVQQCKELMKHHIPSIHF
YSIGAVDSIKEVAKQIY
>A0A1F1QPP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC08A08|TrEMBL
MTTVHPALSYELYPPRSHASCDSLLKTIAELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLALRGDIPPENTRPLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAARLAGVEMPIIPGIMPVTSLTRLTKLCELAGLEVPRELAHRLETASDS
REMHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>E8WLN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp. (strain M18)|TrEMBL
MKIVDKMNRAEQFVSLEFFPPKDKNEWSGFFQVVDRLAQLKPLFASVTYGAGGSTKGDTL
EIVSRLKNEHGLDAMAHLTCIGSYRGDLQLFLDNLAQAGVNNVLALRGDLPKDASPEFSA
CRTLLHASDLAAFIKESHPNMGIGVAGYPEVHPEAIDAEHDLRYLKLKLDQGGDFAITQL
FFDNALYFDFVAKARSIGIDKPIIPGIIPVVSLKVIQRIISLCGAKLPPAYLAELEEADR
AGGAAAVQKVGVAHARRQAEELLAAGVPGVHIYTLNRDQAVLDLVEGLLP
>A0A0Q9P7J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Soil764|TrEMBL
MSPPSLIDAHPNLSDTAPVALSYELFPPRSPAAAETLWTTIRELEATEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIVGELLDTGVRGILALRGDLPKD
ASAPASGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEEHDVEVLL
AKQRSGADFAITQVFFETRQYADLLTRARRAGVTIPIIPGVMPLTSLRRLNRLGELTGVE
PAPQLMARLAAADTDIERLRIGVDATVDLANAALDAGAPGIHIYTFNEHQSALEVLDKLA
LPRRSRPGIRPGSSARGQLAS
>A0A3G5T2R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium YIM 96077|TrEMBL
MSRGLPSTPQGNGPAIRELLAAGERSYSFEFSPPKTPEAEGLFWRTMRELERLRPTFISV
TYGAGGTTRESTVRLTGQVALDTTLTAMGHLTAVNHSVAELRHVIGQYADAGIRNILALR
GDPPGDPQAEWTPHPEGLLYSEQLVRLIKSVGDFSVGVAAFPEKHPRSPDVETDVRYLVG
KFRAGADFAITQMFFNVEDYLRLRDHAVAIGGDKPIIPGIMPVTNVKQIQKFAELCGAAF
PESLAERLYAAGDDREAVRAIGVDYATAMCERLLAEGTPGFHFYTLNRSPATREIYERLG
LVDNTLAPA
>A0A2E7TGB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVTEFLDNKNKTHFSFEIIPPFRGGSIDKVFSLVEDLMRFDPPFIDLTSRSAEEYYQDD
GNGNLVQHIRRKRPGTIGMSAAIKNKFNVETVPHLLCSGFSKEETXDALIELNYXGIKNV
LAVRGDELRNDRNLSKSKNSNFYASDLVKQIKDMNEGRYLEPLXDPXKSDFCIGVGGYPE
KHFEAIDXKSDISRLKEKVDSGADYIVTQMFFDNKVYFDFVDKCRKEGIEIPIIPGIKIL
STEKHLTALPKHFFIDLPKELKDSIQAKTKNEIRNAGKKWAVKQIQELIERDAPCIHLYX
MASSKLASEVVSEFI
>A0A450TUL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. FW|TrEMBL
MIKIMDDQGSKDRVFSFEFFPPRTPEGRDKLRVTWQRLSELNPHFFSVTFGASGSDQSGT
LETVREIQRHSGIDAAPHLTCIGSSRARIREILERYLATDIRRIVALRGDFPPDMTEMGE
FRYANELVAFIRAETGNDFHIEVAAYPEFHPTAPSASADLKNFKRKVESGADSAITQYFY
NQDAYLRFVDSCDRIGVHIPIVPGIMPITNYASLARFSERCGAEIPRWLAKRLEGFGDNM
DALQAFGIDVVTELCHRLLEAGAPGLHFYVLNRAEPVTTIWKNLGLPKIS
>A0A418DET6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces astaci|TrEMBL
MKIIDKINEKIEKKEPFYSFEYFPPKTPAGVTNLYTRMDRMALMEPLFCDMTWGAGGSTA
SMTIELCVNAQKLSGLEMLMHLTCTNMPKGSIKNALDSAKDAGIQNILALRGDPPRGQTE
FKECEGGFAYAIDLVKYIREEYGDYFCIAVAGYPEGHSDAKDLDTDILHLKEKVDAGADF
IVTQLFYDVQKYFDFVDKCRAVGINVPILPGIMPIQNYNGFVRMSSMCGHVPDAILQALE
PIKDNDEAVKDYGVELGIQMCRDLLDHGVPGLHMYTLNLERSTRLILEGLGLTATARREL
PWRPSTLAKRAGETVRPIFWANRPKSYLDRTASWDEFPNGRWGSSESPAFGDLNESYYSH
TTASVQERKAMWGESPVTYADVYETFTRYVMGAVKSLPWCDTPLHLETKSIQERLAAVNR
AGYLTINSQPRVNAAPSDDPMFGWGGPGGHVYQKAYVECFVSPENLKRIIEKCNKMKHVQ
YHAVDVNGNSYSNCGKGTTAVTWGSFPNKEILQPTIVDTDSFMAWKDEAFSLWLSMWASL
YHDESAAHALIHQIRDSFFLVSIVDNNFVNGDIWDAFDLRMPDYEYTVTGYQRMKKRERI
QLGTPVVVNGKKLAIFRHGARYYAMQQFCPHAGGDLALGDIEDIDNMLCITCPRHGFQFV
LLSGDCLIGDAWKAEHYPVEARAALPDTPRTLFVGFPQLNCSLFYEEDF
>A0A1C7MBP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grifola frondosa|TrEMBL
MHLTCTNMPKEKVDIALREAKQFGCRNVLALRGDPPMGKDEWEAVEGGFAHGIDLVKHIR
GQYGDYFDIAVAGYPQTHTLPEEQRVLEMKYLKDKVDAGANFIFTQMFYDIEMFIDWTWN
GFQKATSLAKIQVPQWFLNVLEPHRNNDEKVRELGTKLVADMCRQILKEDIGIKGLHFYT
MNLEKGCRMLLEELNLVPRVETIKPLPWRQSLTPNRRTENIRPIFWANRTRSYLSRTENW
DEYPNGRFGDSRSPAYGELDGYGVWIKQSREEGLKMWDSPTTVDQIRPGTLVRMNVISKQ
LAKLNELGFLTINSQPAVDGAKSDDRVHGWGPANGYVYQKAYLEFFVSAELLDVLIPHIE
RDINITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELG
LQWAKYYEPESPSRKLINNIMETYYLVNVVHNDYKNPKLSSSPSSRPVRSSPPHRLQNSH
SPMATHTSLQHFPNHLSAFDTPPTGGLLYLIPAILTGFNPTTILTATDACFPRILFAFAL
VPFDISCMYPYPRFLHQLHSTPLRFNPRGLCIQLHVSYSELTQYRDDL
>A0A1T2YVU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRSLLTQYKGAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQSFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A5E6XJP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKSAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A7G9TGH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas mexicana|TrEMBL
MPSISFEFYPPKTDEQRAQLDRTADKLKAHAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGSREEIRELLRLYRALGCKRIVALRGDLPSGMGHPGDLRYASELIEFI
RAEHGDTFHIEVGAYPETHPQAEDALTDLRHFKAKVDAGANGAITQYFYNPDAYFHFVDA
VRRLGVDIPIIPGIMPISNFTQLRRFSEACGAEIPRWIGKRMQALGDDADAVRDFGADVV
ASLCERLIAGGAPSLHFYTLNLAKPTQTVLSRLGWAA
>A0A7L4IBD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scopus umbretta|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCHQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRSEFDDYFDICVAGYPKGHPEADSYEADLRHLKEKVLAGADFIITQLFFRSETFLQ
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A8J3Q829|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizocola hellebori|TrEMBL
MPGPRPRISDLLKAGDPTFSFEFFPPKTAEGERQLWQAIRELEPLRPDFVSITYGAGGST
RDTTVSVTERIAADTTLLPMAHLTAVNHSIAELRHVIGRYSDAGIRNMLLVRGDPPGDPQ
GEWIRHPQGVSHADELVSLVKASGDYCVAVAAFPEKHPRSPDFESEVRYFVQKCRAGADF
AITQFFFNWEDWARLRDAASAQGCQVPIIPGVMPVTNVSQIERMAQLSGAVFPAKLAERL
RAVADDPVAVRAIGVEVATEFGARLLAEGAPGLHFITLNRSTATREVWQQLRVGASV
>I4D6P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus acidiphilus (strain DSM 22704 / JCM 16185 / SJ4)|TrEMBL
MAEEKSKLQSLFEQGEFAVTCEIGPPKNAQGDGIRNHSEHLKPFVDAVNLTDNQTAIVRL
SSIGAGVHVLAAGGEPIIQMTTRDRNRIALQSDLLGAYSLGVRNVLCLSGDHQTFGNHQG
AKNVYDLDSIQLIQTVKDMRDAKVFQSGEVIKQGEPRFFIGAVANPFADPFEFRVLRLEK
KIRAGAQFIQTQCIFDMERFEAFMDLACKRGLHQQAYIMAGVMPIKSAKAAKYMQKNVSG
MLVPDGIVERMSKAEDQPAEGIKLCIEQIKHLRTVPGVRGVHIMAVAWEEIVPEIVKGAG
LLPRP
>A0A2C5B2F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pseudomycoides|TrEMBL
MKILDLVSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADIIQTN
TYGANEAKLRMYGLENQVTQINKAAVKLAKAAVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEKVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQLALHEAGATQNGN
DVNGILTQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPAHIEGMKRVIANVTPVTEKQIVQRQQVVH
IQTKRASTHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIIEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIEEIYEATKHLEKPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMDGHETQESAIEEGIRISQELINAAMKYFNGIYLITPFLKYEITENLVKYVK
EKQDVKEGIN
>A0A532D0A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPQRLVDVLNRGTFAVTVEYNPPKGTNITSILENAKQLVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVRGLNNGKDMVGNKLDGSTAFTIGAAVTPEADLVGPVLAKFEVKV
KAGAQFFQTQAVYHPDVFAGFMKQVRPFNVKVLAGILLLRNAKMAEFMNANIPGMSVPSE
MIDELKAAGEKAEDVGVDIAVRTIKAVRPHCDGVHIMAIKATHRLSEIITKAELD
>C8P9U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limosilactobacillus antri DSM 16041|TrEMBL
MTSLSYEVFPPNSAVGINHLNQVLAALQGLAPSFISVTCSSKAARLAQETVRVADYVENC
CHVPAMAHLPAWYLSRTDVDRIMAQLRERHVGRVLVLRGDERPGLAKKDDFPHASDLIAY
IRQNYPDFQITGACYPEKHPESLDMVAELQHLKLKVDAGCDQIITQLFLDNRCYYRFREL
CAIAGIDVPIIAGIMPIINERQANRILRTSAVAVPEKFKDILAKYHDHPEALKQAGISYA
IDQIVDLVTNDVAGIHLYTMNQADTARQVEQNIGALLQVSC
>A0A1I0ZSD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis marina|TrEMBL
MSTHESALLRHYLLNARFEVLPLRGVVEQASDLPAGSTVTVTSSPRKGTEATLDTAERLA
GIGMRVVPHLAARMIEDRRALEALLDRTAGLGIDEVFVVAGDVDKPVGEFGDSLALLRAM
TELGLRPARVGITGYPERHSFISDNATIQAMSEKAHHADYIVSQICYDPTTIATWLRSVR
ARGITLPVHIGAPGVVDAAKLLRISLKIGLGDSVRYLRSQHSVLSRLLTRYTPEELLTQL
TPAVLDPANRIAGWHFFTFNEVNRTREWSHQLAARVQEVPA
>A0A3D4N6H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerochaeta sp|TrEMBL
MKVTEIIAQAKGPLFTFELLPPLKGHTMDAINETIETLLPYNPAYINITNHQMEVVYVDR
PDGLVERRTTHKRPGTIGLAAAIQYRFGIPVVPHLICGGQTKEQLXVELNFLGIENVLAL
RGDPPHGERRFIAAKGGYDHTDGMVSQIAAINRGEYLDPTLRDPVATSFCIGVAGYPEKH
AEAPNFNHDITMMKRKIDAGAHYIVTQMFFMNERFFEFVDQCRAAGIEVPIIPGIKPIQR
RSDLDLLPQTFRVDLPVSLVDRIERCKTAADIRKVGVEFCTAQVAQLLEAKVPGVHFYTQ
GRAEPIANVVEATYPKAILS
>A0A172YPU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NCu2D-2|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLITVHQELQKLNPEFFSVTYGAGGSTRERTLKTLDDFN
GKGTPVAPHLSCIGDSKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDKDIQRFCDKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLADYGDDTASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A072CU32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ETR1|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKLVHQELQLLNPEFFSITYGAGGSTRERTLAAIADFN
GKGTPVAPHLSCIGDDKVRIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADNFDADIKHFAEKVKAGANAAITQFFFNPDAYFYFV
ERIQKQGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVIKLCERLIAGGAPSLHFYSMNHTEPNRQLVLDLGLA
>A0A5V8Y393|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Kalamu|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>C4ISD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella abortus str. 2308 A|TrEMBL
MMGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGST
RERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIG
EKYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATR
AITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERF
DGLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAA
LEVA
>A0A1H0UXC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas guguanensis|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLAAYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELLELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEVAAYPEMHPQARNFESDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLDLKR
>A0A3N9RRK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. LASN5T|TrEMBL
MATPLIHPNWDKAPDGITDGFSLEMTAKDEASLRDAAPLIPADTPIAVTFLPGEDVAARV
AATVAVRELGFEPMPHFSARRILSEDDFEGYLKAVVEQAGVERCFIVAGDPPEPQGPYFD
TSALIATGAFERAGIKAIGVGGHPEGHPNMTVAECWAVLEKKVAEIERRGMAPLIVTQFG
FDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVTN
LLGSAGPDKLVNAFAQGLGPEHGRVRLHFYPFGGLVKTLEWIHEYNRKHGI
>A0A017HQC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubellimicrobium mesophilum DSM 19309|TrEMBL
MPTVSFEFFPPKNLEGSFRLWDCCNVLGPLMPEFVSVTYGAGGTTRTLTHDAVGTIHKHY
GLTVAAHLTCVEASREETLAIADSYADVGVTEIVALRGDPPKGEEGFRAHPDGFGSSVEL
VDALARTGKFKVRVGAYPEKHPEAADHAADIEFLKRKIDAGATSAITQFFFQPETFFRFR
DDCVKAGITAPILPGILPVESWAGVKRLTARCGTSIPPTTAHAFENAERDGTTELLAVAT
AASLCDRLVEGGAEHLHFYTLNKPSLTRDVCLALGIAPRARLQAVA
>A0A1W9S825|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium 4484_95|TrEMBL
MPVDFRERLKTGIVICDGAMGTYLNQKGISYDHCFDELNLSKPELILQIHQEYIDAGAEM
IETNTFGANSARLSGYGLEDKVREINIGAVRIAREARDITGQDVFIAGSIGPLGKQLLPY
GRISPQSAFKVFIEQVEALLEGGVDLFIVETISNLEEMELAVSAIRKVTKLPIVGQMTYT
AEGKTFLGNSPEEVVSRLALLDVDVIGANCSVGPQKMLEVIEVLAEVGTGYISAQPNAGL
PRLYAGRFVYFSSPDYFADYARKFVNTGAIIVGGCCGTTPEHITAVSKKLKDIHPVRNKR
QTSPHIKVREIREEKTTGLMSPFMVKLLRKFVVTVEIDPPKGTNPDRLIEVVGQLKEAGV
DAVNIADSPMARVRMSSLAMAYLVKQNIDIDTILHFTTRDRNLMGLQSDLIGAHAIGIRD
VLALTGDPPSLGDYPNATAVYDVDSIGLVEIITKLNSGYDFSGNSIGKSTHFSIGIAVNP
MAPDYQLEMNRLRRKIAAGGQYIFTQPLYDIKIINSFLDDISTYNLPIILGILPLVSYKH
AEFLHYEVPGIDVPVTIRQRMKKAKSRSTEEGKLIALEIIDKIKKSVAGLYLMPSFGKFD
TCLNIAKEILN
>A0A839RQE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoyosella altamirensis|TrEMBL
MTRQQTPTEVLVSLLTRVRYEVLPTEKVLDEVCATLPPGATVTVTASPAKGQQATLHIAE
RLAALGFDVVPHLAARMISGPGELAEITSRLQSARITKVFVPAGDGDTQGRAYSSALELL
EDLSNTGNPFSEVGITGYPESHPHIHDDLTIQAMWDKRQHATQIVSNLTFDPGVLSDWVT
RVRARNVNLPIFVGLPGPVERTKLLRMATKIGVGESARFLAKNGGLFARIATPGGYDPAR
FLGRAAPALGRNGMNIAGLHLFTFNQVAETEAWRTAQLARLLGHRKSYGHIQASELPLAG
TS
>A0A7W9EIK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas yantingensis|TrEMBL
MTLSVGQLEEARRALDGPLFADVAGDADVSFEFFPPKTEKMEAAMWEAVQTLAPLGPRFV
SVTYGAGGTTRDRTHATVARIARETSVPAAAHLTCVEASRDEVDAVAREYWAAGVRHIVA
LRGDPPTMGEAFVPHPQGYASAAELVAGLKRLHPFEISVAAYPEAHPEATSASADIDNLK
RKLDAGATRALTQFFFEPETFFRFRDAAAAAGIGAEIVPGILPVSNYAQTQKFAGMCGAA
IPDWMGRLFDGLDAHPAARQLVAATIAGELCRRLYAGGVRHFHFYTLNRAELSYAICHML
GLRPKAQAALAAA
>A0A6P0NUQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO2C2|TrEMBL
MNRFRNAVKSGEFLVTAEVAPPKGANPAHMIEMASTLKGRVHAVNVTDGSRAVLRMSSLA
ASIILKNNGIDPICQVACRDRNRIGLQADLMGASALGLHNILALTGDPVKAGDHKDARSV
FDMESVRLLKMIAKLNQGMDWNEKALPDGATDLFVGAAVDPQSPSWSGLKKRFERKLLAG
CQFFQSQLISDFDKLEKFMNQIAVESNKPILAGIFLLKSAKNAAFINKYVPGVDIPEHII
NRLAKAEKPLEEGMKIAAEQVQIASKICHGVHLMAIKREDLIPRILDMAEISPI
>A0A4Y8MF78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. DMF|TrEMBL
MTTPAISFEFFPPRTLEQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAG
HYGLNVAAHLTCVDATREETLQIVADYAAAGVHEIVALRGDAPQGQDRFTAHPEGFASSV
ALIEAIAARGDMTIRCGAYPEPHPDSADTAADVAWLKRKVDAGASSAITQFFFDADTFFR
FRDACAAAGVAAPIIPGILPIQSWAGTRRFAERCGTSVPQWAEEAFAAAGPEGEAALALD
VCVKLCESLVEGGVDKLHFYTLNKPDLVQKVCAGLGVAPKAEFSRVA
>A0A0Q3WYD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Margalitia shackletonii|TrEMBL
MNLLDRLKNSILVADGAMGTLLYSYGKDTCYEEFNLSHSEDIFNIHQAYIQAGAQVIQTN
TYGANYYKLSQYGLEEQVKAINIEAVRIAKQAANKDTYILGSMGGYRGFRKADITLAEIK
RSFREQLYHLLHEGVDGILLETYYDAEELFAVVEIAKEEADVPVIAQFSLLEPEVLQNGT
YVKDGLLRLEELGADVVGLNCRLGPHHMIQSFEQIPLPNRAFLSAYPNASLLDYEDGRYV
FTKNAEYFKSCSVRLVEQGIRLIGGCCGTTPEHIKAIAEGVRGLQPIKEKTVKPIRPKIE
VLASHVDQEPPLHEIVKERTSIIVELDTPKHLQTEAFFAGANCLKEAGIDALTMADNSLA
SPRISNVAMATILKEQHHIRPLVHITCRDRNLIGLQSHLMGLDALGINQVLAVTGDPSKI
GDFPGATSVYDLSSMDLIAMMKQFNEGISYSGKSLGKKTSFSVAAAFNPNVRNLDRAVAR
LEKKVRSGADYFITQPLFNEKQMEEVYEATRHLEVPIYIGIMPLTSYRNASFLHHEVPGI
TLTEQILEVMERVKDDPVQATKESLSISKTLVDAAMKYFNGIYLITPFTRYDLTVDCVNY
VHEKEKLAHGTNVI
>A0A4Y8P290|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. DMF|TrEMBL
APLPGHASRGRLERVLRRGEFAVTAELNPPDSADPEDVYERAAVFDGWVDGINAVDASGA
NCHMSSVGICALLTRMGYAPIYQISCRDRNRIAIQGDVLGAAAMGVQNVLCLTGDGVQAG
DQPGAKPVFDLDCMSLMETIRTMRDEGRFLSGRKLTTPPAMFLGAAINPFAPPYDFRPLR
LAKKIAAGAQFVQSQYCFDVPMFRDYMARVRDLGLHEQCFILCGIGPLTSARTARWMRAN
VPGVHIPDAVIARLEGAADQKREGKRLCIDIIDEVKEIAGVAGIHVMAYRQEEYVAEIVH
DSGVLRGRRPWRPEPRADDALVAGRLDHILHDDRAETPQQILTDAQAAPHPATP
>L0MX63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Blochmannia chromaiodes str. 640|TrEMBL
MSMFHATQQAVLNQYLAELQGNINVSFEFFPPRTDEMEQILWKTINKLSKLNPIFVSVTY
SAHSGTRNYTDKTIKDIKKRTGLIVAPHLTCINETPQALQTIAQEYWNNGIHNIVALRGD
QIKKNYQSSMYASDLVYLLKKIGNFDIAVAAYPEVHPEAKNAQSDLINLKKKIDAGANRA
ITQFFFDVEQYLRFRDLCVSVGIDIEIIPGILPIFNFRQLQHFITFTKVKIPHWIYVIFH
GLDHDLETQKMLGTFVAIDMIRVLLKEGVRNFHFYTLNRSDLTYAICHTLGIKNNKI
>A0A1J4RH71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium CG1_02_46_17|TrEMBL
MLSSSPIALSFEFFPPKNDEGRKALLAAAHELAVLDPAFVTVTFGAGGSTKSGTFEAAKL
LQQDCGLNVGAHLSYFGTPKAELFAYADQLWDAGIRHLVALRGDIPQGQSPANFKEPDYF
EYTSEFVEALLKRHPFDISVGAYPEKHPDAPSLDADLIALEKKCSAGAARAITQFFFDPA
IYQNFVSQARNKGILTPITPGLLPIRDFNKICGFAEKCQAHIPQEFKEIFTNSSDPVATG
IDLLSRQILALKEMGVSHFHFYTLNHSDMVIGACRQARIRL
>A0A2H5PXY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrus unshiu|TrEMBL
MKVIDKIQEKVASDKVVFSFEFFPPKTEDGVENLFERMDRMVAHNPAFCDITWGAGGSTA
DLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDK
FVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLK
KKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTVHLYTLNMEKSALAILLNL
GLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRTVGWDQYPRGRWGDSRNP
SYGALSDHQFMRPRSRDKKLHEEWAVPLKSVEDIYEKFKNYCLGKLRSSPWSELDGLQPE
TKIINEQLGKINVKGFLTINSQPAVNGERSDSSSVGWGGPGGYVYQKAYLEFFCSPEKLT
ALVDKSKALPFITFMAVNKEGNWKANVNQTDVNAVTWGVFPAKEIIQPTVVDPASFKVWK
DEAFEIWSRSWASLYPEGDSSRKLLEEVQSSYYLVSLVDNDYINGDLFTVFADL
>N9MYM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 298|TrEMBL
MTKRVPISFEFFPPKTDVGAEKLRTVHQELQQLNPEFFSITYGAGGSTRERTLAAIHDFN
GSGTPVAPHLSCIGDDKTRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREYSGDHFHIEVAAYPEMHPQAESFDVDIQRFVEKVHAGANAGITQFFFNPDAYFYFM
ERLDKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSKSIKAFGHE
VIVKLCERLIAGGAPSLHFYSMNQTEPTQQLVVDLGLN
>A0A0Q9R8G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Soil777|TrEMBL
MIQGRGRSMRQRIEDGERSFSFEFFPPKDAEGEEQLWRAITELEPYDPTFVSVTYGAGGS
SRDTTVRITGRIARETSLVPVGHLTCVGHTRDELEAILDSYAEAGVANVLALRGDPEDGP
RADWTPTEGGLSYASELVELASRRGDFAVAVAAFSLGHPSAASLEEDARVLLAKQQAGAE
FAITDMVFSADDYAGLLERSAAVGVDIPLLPGIMPILNLRQVSRMAELSGHPVPDAVRTR
LTPYEHDPAGLRAEGIAMAAELCEALLDAGAPGLHFYTLNRSRATREIFSALRISV
>A0A7W2R4W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gelidibacter maritimus|TrEMBL
MKVTEHIAQANGNTQFSFEILPPLKGQHIKSIFDNIDPLMEFKPPFIDVTYHREEYIYKE
QENGLLKRQIVKKRPGTVGICAAIQNRYKVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VMALRGDAVKTETYFTPEKEGHEYANGLVKQINALNDGVYLDEELQNTSKTNFCIGVAAY
PEKHMESPSLDSDIHFLKKKIKSGAEYVVTQMFFDNQKYFEFVEKCRKEGITIPIIPGLK
PIATKRQLNLLPHRFHVDLPEALILEVIKCKDNSEVKQVGIEWCIQQSKELQKAGIPVLH
YYSMGKSDNIQTIASQVF
>A0A5X0EYC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Duisburg|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6A5BUH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naegleria fowleri|TrEMBL
MKIIDKINQCIEENKTFYSFEYFPPKTDAGVENLYQRLQRMTKFAPLFIDITWGAGGSTA
GKTIEIGATAQNMIGVETQIHMTCTNMKVEELDKAIQTAKDLGISNILALRGDPPLGTEE
WEQTDGGFTHAKDLITYIRNKHGDYFGVSCAGYSEGHPDGDYEKDLHFLKEKYDAGADFV
ITQLFYDWQQFLKFVKDAREIGIKCPIIPGIMPINNHSSWQRMTSFCKTRIPEEMKEEMS
KLNLEDDNEVKAYGIKLCITMCRALLNNGIRGLHFYTLNLEKSTESILEGLELCPKESIP
RSLPWVKPANAKRLTEEVRPIFWSNRVKSYIDRTQHWDEFPNGRWSDSRSPAFGELGEEI
AYFYRRKFGDKENQITAWGKEHDSIESISNVFVNFIEGKIPFLPWNEQHTSPETNIIKDQ
LVFLNKHGFLTTNSQPKVNGVPSSDKNVGWGPKNGYVYQKAYVECFISPAQLDVLEKVVA
EKYPMITYQALAKDGKARSNIREDSTYVNAVTWGVFPGQQILQPTVVDSNAFLVWKDEAF
HILDTHWLSLYDENSNAHKLLKSISDEWYLLNIVDNDYIHGDIFALFKDVVARKQ
>A0A8J7MSI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fuscibacter oryzae|TrEMBL
MTLSPRISFEFFPPQSLDASFRLWETVQALAPMGPDFVSVTYGAGGTTRALTQDAVATIH
RNYGLNVAGHLTCVGASKAETLAVADTYHAAGIREIVALRGDAPQGADRFTPHPDGFANS
ADLVEALARTGKFKIRVGAYPEPHPDAANTAQDVTWLKRKIDAGASSAITQFFFSADTFF
RFRDACAKAGISAPIIPGILPIQSWSGVKKFASRCGAQVPQKLDEAFATAARDGREDLLA
LTQCVALCDRLIEGGVEDLHFYTLNRPNLTREVVRALGLSSEITLEKVA
>A0A7W6LRW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium scionense|TrEMBL
MTQIDRAQHHSEGPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFVSVTY
GAGGSTRERTHNTVARIARETPLAAAAHLTCVAASKAEIDEVADAYWEAGVRHIVALRGD
PPEAGTAFQPHPDGYKGAAELVEGLRKRHDFEISVAAYPETHPEAQSAQSDIDNLKRKID
AGATRAITQFFFEADSFFRFRDTVAAAGIDAEIIPGIMPVSNFAAVQRMSAMCNTDVPAW
MGRLFDGLDQHPAARQLVSATLAAELCRNLYMGGVRDFHFYTLNRAELSYAICHLLGLRP
QVAAELMA
>A0A243SXH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas desiderata SP1|TrEMBL
MSSSYPLGISFEFFPPNTEAGREKLIGVRDALAERGPRFFSVTYGAGGSTQGRTLSTVRS
VRESGITTAPHLSCIGSEKAQLRDLLAQYREEGIDSLVALRGDLPSGMGGIGELRYANEL
VEFIREETGDHFEIAVAAYPESHPQAPSFERDLENFARKVKAGANLAITQYFFTAEAYFH
FVERAQALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAFG
TEVVSRLCQRLLDGGAPGLHFYTLNQAEPCLRILDNLA
>H0E6I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Patulibacter medicamentivorans|TrEMBL
MRIDEIIAAADEPSFSFEFFPPKTDEAEERLHEALETLRELRPSFVSVTYGAGGSGRDRT
INVVKNLREQHGLEAMAHFTCVGGTKDEIRDVLQQMREAGIDNVLALRGDPPGGEGRFEP
TPGGFASSPELTKLIADEFDFTVGGAAYPEPHPDARHEDDDIETAKAKVAAGARFLITQI
FFDNRDYFAFVDRLRAEGVDVPVIPGILPITAIGQARGFAKKIGARIPEGLERELDLRED
DPDGIKDLGVSYATLQCAELLANGAPGIHFITMNRSPSTRAILSTLRLHRPWERTPFAAT
GDGATAR
>A0A3A3YYN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vallicoccus soli|TrEMBL
MVAGPALHRPAAPTVRDLLRSGRRSFSFEFFPPKTDEGERQLWTAIRRLEPLRPSFVSIT
YGAGGSTRDRTVAMTERVATETTLTPVAHLTAVGHSVAELRRVVGSLAAAGVRNVLALRG
DPPGDPQGEWVRHPEGLEYAEELVRLVRASGDFCVGVAAFPERHPRSPDWDSDIRHFVRK
CEAGADYAITQMFFRADDYLRLRDRVAAAGCEVPIIPEIMPVTNVRQIERMAQLSGAAFP
ADLAAALHAVEDDPAAVRAVGVEHASRLSERLLAEGVPGLHFITLNRSTATLEIYQRLGL
GRERA
>A0A4Q7S119|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus agavae|TrEMBL
MTDRYFSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSTRENIREILSAYRAGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFHIEVAAYPEYHPQSRSPRHDLENFARKVKAGADSAITQYFFNADAYFRFVD
EARATGVEIPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKKLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNTAAATKAIWQRLKL
>A0A248W6B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. 11515TR|TrEMBL
MSHIDENPLGVHLPLDPLPGHYSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPRVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLHEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGISGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRTDALVAERLHQISEGREENQQAMAEIAA
HHTPPQTH
>A0A067QEW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jaapia argillacea MUCL 33604|TrEMBL
MKLSDKIAEYRLNHPWYTFEFFPPKTDQGFENLLDRISRLAALNPLGVSVTWGAGGSSRE
RSLELAGIIQAENGIDTVLHLTCTNMEQGTVDEALRGAKERGIQSILALRGDPPRGEEYW
IPTDPRFNHAIDLVKYIRSSPEFSPQFCIGVAAYPDGHPDHDTDEDGEIAYLKAKVDAGA
DFIMTQLFYDVDNFSRWLRKIRKMGIAVPVIPGIMPIQTYSSFLRLTKLCGTRVPASLAA
ALEPIRNDDSKVKEFGVTLATDIIRRITDEDDIFGVHFCTLNLEKSVQRVVEDLGWHGRS
PVIKNRLITEAPDFNYAPVQPRSSSLVIDPYNASDSATKGLADHHIHPTGDGRGEVNNAS
SWDEFPNGRFGDFKSPAFGDVNQWGGSAVSRNVALSQWGNPKSIADITSIFLSYLHSQTQ
STPFYPDPLSAESSLILQHLEKLTQRSWWTVGSQPAVDGAPSTDEIFGWGPSAGYVYQKG
FVEFFAEKADVEKIEKKIQEEGSGWVDYFAGGIDGECVTNVPEGGRNAVTWGVFPGQEII
QTTIIEQESFLSWKDEAFSIWAEWASFYPPESEERKLLESITRDRWLVSIVHHDYRNPLA
LWNFLFEGTPIL
>K9X0L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cylindrospermum stagnale PCC 7417|TrEMBL
MPPDTHSIPVLNTFRSAALAGEFLVTAEVAPPKGGDPTQMIKMAATLKGRVHAVNITDGS
RAVLRMSSLVASAILLQNGIEPVCQMACRDRNRIGLQADLMGAHALGIRNILALTGDPVK
AGDHPEAKAVFDLEAVRLLQLIRKMNQGVDCNDKSLTDGTLDLFAGAAVDPQSKSWSGLQ
SRFERKIEAGAQFFQSQLITDFERLEKFMDAIAAGYKKPILAGIFLLKSAKNAQFINKAV
PGVNIPQHIIDRLAKAKDPLEEGMQIAAEQVQIARQLCQGVHMMAVKREDLIAPILDLAG
VEKIS
>A0A830IR69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus lentulus|TrEMBL
MRWLKFSSINFNYPRYFSLHREEIRVKMEKITDKIAALPPNENYFSLEFFPPKTQMGFSN
LTARLERMSQALRPLFVTVTWGAGGSTAARSLELAEICQRQLQLTTCLHLTCTNMSRALI
DEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCL
GVAAYPEGHPVDSYQDVQDPVRDLPYLVEKTLAGADFIMTQLTYDIEAYTKFEEMLRNHE
SGAFKTIPIIPGLMPIHSYKILTRTTKLSHVKIPPQIMASLEAVKHDDDAVKRIGVDVLS
DLVEAIKKIPCPGFRGFHFYTLNLEKTVSFIIERCGLIPDYPEDTNAVVDDDYTTAPTGA
QNRSLSRRRASSVNSHPHNRVIVDRLQVPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQ
ISEGQGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVSGAVARRIWGYPVSREDI
SALFRRHVSGDLYIVPWSEGGAEENSSGLNAETEVIRPELLKLIDSKGWWTLASQPAVNG
VRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFQTVLKPLFAKHGHEKLAWFATNVKGEF
ESSLPADPAHADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWR
RVYPRGTPTERLLEEVKNDVWLVCVVGQDFGAGTENGSEEEQQETKWMWNVLINSQ
>A0A737C9L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. arizonae serovar 18:z4,z32:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6H0ISE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquisalimonas sp. 2447|TrEMBL
MESQKKHSPVFSFEFFPPKNDEGEERLRKTRERLQALGPRLFSVTFGAGGSTRERTFETV
IDIQKRSGIDVAPHLSCIDATPDSIRELLNRYRDNGIRNIVALRGDMPSGTGGGPGHFKY
ANELVEFIRQEHGDHFHIEVGCYPEIHPEATDAFSDLENFKRKVEAGADSAMSQYFFAPE
GYYRFVESCEKMGVTIPIVPGIMPIVNFQQLARFSDMCGADIPRWLRKRLEAYDAKGDKE
SMQAFGIDVVTQMCADLLDAGAPGLHFYTLNQAKASEAIWNNLGLSQKIAKAAD
>A0A1M4SXA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrithrix thermotolerans DSM 19514|TrEMBL
MVVEIAEQGWTIPMAHLTCAAHSEGELKTILLKYKAANVNDVLALRGDPPLEGDGFLPKG
ELDYAYQLVELAKELADFGVAVAVHPEGHPASKDLKTDRIHLKRKLELADFGVTQFYFTH
EAYERVRDQMSTLGVDRPIVPGIMAPTSWSTLQRMAQLSGTTIPSYVVDLFDSVGGDPKE
IRKVGVDIAIQLCISAIEAGAPGVHIYSMNSAEATREIYDAVKPYLQRD
>A0A1X0T7N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantimonas sp. 22II-16-19i|TrEMBL
MSQVNALSNSGIRVSFEFFPPKSEKMEENLWRSIERLAPMQPTFVSVTYGAGGSTRERTH
HTIERILKETSLVPAAHLTCVDASREEVDEVVRQYRDTGVKHFVALRGDSQAGVGGKYIA
RPDGYRNAVELVAGLKKIDDFEISVSAYPEKHPESPDFATDIDMLKRKVDNGATRAITQF
FFDNDVFERYVERARKAGIYIPIVPGIAPIHDFTKIARFASATGASIPAWLAARFEGLEE
DEQTRSHVSAAFCAEQVLDLTRRGISDFHFYTMNRADLVYSICHILGLRAAAPVGEDAAA
AAAA
>A0A077W9B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lichtheimia ramosa|TrEMBL
MKITDKLQQAKQKGHISYSFEFFPPKTDAGLANLFDRMGRMATLEPYFVACTWGAGGSTQ
QRTLEVCSTAQSVYGLETLMHLTCTNMEKEKIDRALQDAKAAGIQNILALRGDPPRGQEY
WTPCDDQFQHAADLVKYIRQHYGDYFCIGVAGYPEGHLDTPDKDQDLKYLKDKVDCGADF
ILSQLFYDVDVFKNWVNKCRDLGITVPIIPSILPIPTHQSFRRIINLCRIQVPKAILDKL
EEIKSDDQKVKDYGVELAVKMISDLRTSGLIDGIHLSTLNLERSSRLILEQLGLAPSKKP
ELKHRGLAALASDASLVENWDEFPNGRYGDARSPAFGENTYIATQLAPTSEAAKKWGHPT
TVQDITRLFERYVTGDLSSLPWCDEPLQTESDTIQQHLIQFNRQGYWTVGSQPAVNGAKS
EDPVYGWGPKGGYVYQKAFIECFVSDEQLDKLLERLKADPHVTYYATNRKVKCDPIYNLN
LVLTDSFYRVIFQPMWRILRIKTR
>A0A1E4QP23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp. UYMMa02A|TrEMBL
MQDRYYSFEFFPPKTAEGAEKLRNTRAQLAPLNPKYISVTFGAGGTTQQGTLDTVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFQIEVAAYPEYHPQAKSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARAVGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAGGVPGLHFYTLNAAGATKAIWQRLKL
>A0A3E0EDE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium aquicola|TrEMBL
MKVTEHIENAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYQVDTVPHLLCGGFTKEETEYMLVDCHYLGIHN
VMALRGDAMKDEQSFVPKAGGNNYAVDLVAQINQLNCGKYLHDVMDVDNKADFCIGVAGY
PEKHLESPSLQTDLKRLKEKVDAGADYVVTQMFFDNSKYFEFVKKAREMGITVPIIPGIK
PIAVQKHLQILPQIFRIDLPEDLINAVDKCKNNAEIRQVGIEWAIQQSIELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A8ZV44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfococcus oleovorans (strain DSM 6200 / JCM 39069 / Hxd3)|TrEMBL
MRVEQVYEKRKGPVVSFEFFPPRDEKAQGTFDAVIDELTPLKPDYLSVTFGAGGSTKDGS
YQTVKHLTADANLPVVAYVAGYGLSPDTIVNVLDRYRAIGIETIFVIRGDQPREPDFVSH
PESFMYASDLIAFIAEQYDFSLGCAGYPEGHLQAESLEKDIEYLKLKVDNGARYVVTQYF
YDNTFYFDYVEKCRAAGITVPIIPGIMPVYTLKMTRMLSKVCGSSIPASMETALADLADA
PADRVVDFGIEKAVEQCRGLLEQGVPGLHFYTMDRSRSTREILTRLRNEGLM
>A0A836YK10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 1499986|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLDKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A7X8FH25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSCIKPARRWQPRFYPFRRESFRKRFREKIEIMLKGPLWGCRMCGNCLLQETAFICCMEC
PKGLRNGPCGGVTPDGHCYVDPTRRCVWHAIYNRARKTGRTDTLIEVLPPLDWSRTGGET
WADVISQIGKVGSGKFFGSLFSRDREYRKQVWDSVFMTIRQPAWWNGDREYHPAAYTEPA
SELERSLREGRFVVATEITPPLSSDTEKLRKAIEEVRPYVQAINFTDASSAIPRMSALAC
CKVATDLNAEPVFQITARDSTRLSLQGDAIGAGQFGIRNILCITGDSPLVGNPPISDMNI
YDLDAVQMLWILRRMRDEGIYLDGRKMKHPPRYFLGAATTPGALDPELQAIRDQKKVNAG
AQFFQTNIIFDAEKLDPWLEQLDKRNVLGKVSILAGLAPLKSYKTALYLHEKVPGVYLPD
KILSRMEKAGDGAREEGIAIALELIASLKRKKGISGIHLMTLGGEDIIGRIVREAGLDR
>A0A7H8PKT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimarina sp. TRL1|TrEMBL
MKVTEHIKKAKGKTLFSFELIPPQKGKSIQELYNNIDPLMEFNPPFIDVTTSREEFIYID
RDGLLDKKLTRMRPGTVGICASIKHKYNVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFVPTRGGHTYANELVKQITNMNKGKFLHEVIESDNKSDFCIGVAGYP
EKHMEAPSLDADLRRLKEKVDAGADYIVTQMFFDNKRYFSFVEKAREHGIEVPIIPGIKP
VAVQRHLQLLPQVFKLDMPDELVRAVEGCKTREQVRQVGVEFAIQQSKELLDYGVPVLHY
YSMGKSDNIKQIAEAIF
>A0A838JXU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacteraceae bacterium|TrEMBL
MAEFLRHPGYEVIPLEGTEESVVEHVPKDLALTVTASPGKGTRATLDLAERLAGHGFRVA
PHLSARLIRDRTELGEILQRLREAGIRDAFVVAGDVDEPTGEFEGAAGLLQAMSEIGHDL
DEVGITGYPESHPKITDEMTIQAMFEKAPYATYIISQICFDPGVTSEWARQVWLRGVKLP
IRVGMPGYVNRQKLMRISASIGLGESARFLMRQRNWLLRLLLPGGYSPGRLIEGLKPGFA
DPESNIRGLHIYTFNEVQETEAWRRKMLGRLGSS
>A0A806I3V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis HD-789|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A829K961|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii EGD-HP18|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLDKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A7J6TVK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perkinsus olseni|TrEMBL
MARLIDKIQDRWDHDRDNGESTRVPFFSFEYFPPKTDMGVQNLYERLDRMAELGPMWIDV
TWGAGGSTSGKTFEICRNALTYHGLDVMMHLTCTDQPVKEIDEVGIRNILALRGDAPMYS
SEWKACQGGFSHAVDLVRHIRGKYGDYFCIAVAGYPEGHLEAESMEEDLAHLKEKVDAGA
DLIITQLFYDTEVFFNFVAAVRALGIQVPIFPGIMPIQSYSGFKKMTEFCKTKVECFNLG
APVVRIFLGRSAQLMLCA
>Q0FHJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger bermudensis (strain DSM 26914 / JCM 13377 / KCTC 12554 / HTCC2601)|TrEMBL
MQRPDISFEFFPPRNIEATFRLWDTVQSLAPLDPRFVSVTYGAGGTTRELTRDVVATLHK
HSGLKVAAHLTCVDATKSETLAIAEQFNAAGVSDIVALRGDPPKGATGFTPHEDGFSSSV
ELIEALREAGDFNIRVGAYPDIHPEAASGQADVDWLKRKLDAGASEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGILPIENWKGARRFAESCGTKIPAWVIEAFEKAERDGRQDLLAT
SICTELCSELLDGGVDKLHFYTLNRPELTRDVCFALGVTPETKLEHVA
>A0A389LXB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSVIDLLNAGKKTAFSFEILPPLKGNSFEKVCNVIDKLRVFDPQYINITTHHSENIYKTL
PDGSLHKTNVRKRPGTVAIAAAIQNKYGISAVPHVICKGFTKDETEYGLIDLNFLGVHDL
LLLRGDANKLEKDQIPEGQSHAHTIDLQEQVNDFNEGIAVDGSTFEKMKTPFSYGVACYP
EKHEEAPNMDSDIYYLKQKIAAGASYAVTQMFFDNEKYFAFVDRCRSEGITVPIVPGIKP
LVLLSQLTVLPKIFRSDIPEALAKELRKCSSDEQAKAVGVEWCIAQCKELISRDVPSLHF
YTLMATESVRKVAEAVY
>A0A0H3CTI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCTC 10005 / WDCM 00083 / NCDC 279-56)|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATGDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A243KJC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar iberica|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7C6E1F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus tengchongensis|TrEMBL
MKIRDLLKARKGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRERS
VLWAKRILGLKLNALAHLTVAGQSRKEVAEVLGRFVEVGVENILALRGDPPQGERVFRPH
PEGFRYASELVAHIRARYGEGLSVGGAAYPEGHPESTSLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRVGIEIPILPGIMPITSYTQLRRFTEVCGASIPGPLLSRLEKYQ
EDPKAILEIGVEH
>R7R3X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:100|TrEMBL
MNIQEYIRTHKLITDGAFGTYYADRFQTQDMPELANISFPQRVTAIHQEYIEAGARLLRT
NTFASNTILLHADMNEVRANITAAVNLAKEAVKGREDVFIAGDIGPIPSDEVISREELEE
QYYQIARVMLDQGLKILTFETFHELQYILPAIGRIKEEAPDTFIMVEFTVNQFGYSSAGL
SVKSLLKDASACKDIDAVGMNCGIGPAHMEKLLDQAGVGISGTKYRIALPNAGYPRRTSS
RIRYSNSSAYFAAKVEEMAAQCELDIVGGCCGTTPEFIRQLSQGLDTTPCPPRTAAETSK
TEQVVPQRKGFLYDEQGNLKKKKLIAVELAPPMGADDEKVLEAARLLQKSDVDVLTFPDS
PSGRTRIDSVLMAEKVRRETGMEVMPHICCRDKNAIAMRSLFLGAYINDITNMLIITGDP
VPSLVRQTIKAVFNFDSVGLMKIAQEMNTENFPARPLSYGGAISQGRKNLDVEIMRVKKK
MEAGAEFFLTQPVFSKEDAERVRRIKQETGTRILCGIMPFVNKRNALFMKNEIAGIIVPD
EVIARYPENGTKQEGEAVGVEIAREIMEFTADFADGYYFSFPFNRVYLLEQILR
>A0A7K4W4F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tachuris rubrigastra|TrEMBL
MVNETQQSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAAGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGHRVTCMPWNDDPLATETNLLKDHLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6P1LLZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter dispersus|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKLVHQELQLLNPEFFSITYGAGGSTRERTLAAISDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDSDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERITKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1Y1WIE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Linderina pennispora|TrEMBL
MKIVDKINKALEDDRCFWSFEFFPPKTQQGVVNLYDRIERMCNLGPLFVDITWRWGGKSS
DLTLELCSNSQTVYGVEANMHMTCTNTNFGLIKEALAKAKDQGVQNILALRGDLPDNSVE
FDPEMGEFKYATDLVRYIRQTYGEYFCISVAGYPEGCMCPEDVDKDIAYLKEKQDAGADI
VVTQLFYDVDNFLHWVDKCRAAGITMPILPGIMPIQNYSGFKRMTELCRIKVPQEIWDRL
EPIKDDDQAIKDYGIEVAAEMISKMRKAGVRGFHFYTINLERSTRLTLERLDLVPTVEEV
RPLPWNPSLSQKRAGENVRPIFWRNHARSYIQRTESWDEFPNGRWGDARSPAYGELLHGV
QVRLNPQQALRKWGTPMDVDAVKQLFVKYCQGKLDALPWSEGALQPETEIIQQRLADMNA
KGFLTINTTRSTAGGPTNGFVYKKAYLEFFVSPENLTQLLQRLDSQPTATYYAVNKAGEL
RTNCREDGPNAVTWGRISFLAWKDEAFDFWNAWSRMYEKDSEAAGLLKKLGDEWFLVNIV
ENNFQKPSESIFELFDGLGQPLVNGTA
>A0A4R4XI62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella turkmenica|TrEMBL
MMARPTRADVLRALLSRVRYEVLPTAGVVDEVCAGLPSGATVTVTASPSKGLDATLQVAE
RLAELRYDVVPHLAARMIDGPGRLAEITSRLHSAGITKVFVPGGDADPAGAYDCALQVLA
ELTRTGHPFTEIGIAGYPESHPAINDDLTIQAMWDKRSHATLLVSNLTFDPHLLASWVRR
VRTRGVQLPILVGLPGPVERARLLRMAPKIGVGESARFLAKNGGLFARIAAPGGYDPLRL
LGRAAPTLGREDMHIAGLHLFTFNQIAETETWRVAQLERLDGGRGHLVARPVTRAQEWGV
R
>A0A0B5E0C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Celeribacter indicus|TrEMBL
MPEASLSVLPARLIDGDISLELPPDAVDKFRPDAKVLSPGAKVFLPHLEGKPPEQQVAAA
KALIDMGYTPVVHLGARHFATEADFVRHLEAHSANGVTHALFLGGNPARYSGPFGQALDL
LHHPSLHDSGIRRAFLGGYPEGHPDISEDRLDAALSAKIDRCHDIGLAPEVVTQFAFDGE
VLAGFAWRMQARHPDVPVRLGLAGVTSLPKLIRYAIMCGVGPSLSVLKKSSGKLLGVLAD
KDPSDVANVIEQRITDHDGRVELHFFPFGGWQKTLDWLQRYRETP
>A0A1U9JP37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquaspirillum sp. LM1|TrEMBL
MQSQSNPRTFSFEFFPAKTPEGMAKLRTTRQQLAQFKPEFFSVTFGAGGTTRDRTLDTVL
EIRGEGYAAAPHLSCIGSSRDNIRAILNEYRNHGIRHIVALRGDIPSGMLEVGEFRFANE
LVEFIRAEHGEHFHIEVAAYPEYHPQARTAHEDLRNFANKVKAGANSAMTQYFFNADAYF
AFVDEVGALGVDIPIVPGIMPINNFSQLARFSDACGAEIPRWLRLKLQSYADDVPSIRSL
GLDVVTNLCDRLLAGGAPGLHFYTLNQAGAVSTICQRLGL
>C7LD43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella microti (strain CCM 4915)|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A520J0H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKIVDHIKNANGKTLFSFELLPPIKGQSIQGIFNAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNKYRVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDSSFIPTPNGHAYASELLQHVADMNKGKYLHDDMESPEKTDFCIGVAGY
PEKHFESPNLDTDFKYLKHKVDCGADFIVTQMFFDNKKYKAFVDKCRQNGINVPIIPGLK
PITSSKQLISLPKIFHLDIPLELSEAVQACHSEKEVKEVGIEWMINQCKELKEMGAPVLH
FYTMGNPEPTKRIAQAIF
>A0A5B8D202|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methylopumilus planktonicus|TrEMBL
MPKKISYSFEFFPPSSPEGIKNSKDTRQQLSAFKPEFYSVTFGAGGSTRDLTLETVLEIK
QEGFNAVPHISGISSTKAEIKTLLDLYQQHNIKHLVVLRGDVPHGAVSRGEFKHANELVS
FIRQETNDYFHIEVGAYPEYHPEAVSSQTDIQNFKNKVDAGANSAITQFFFNADAYFRFM
DECLIADINIPIVPGVMPIYNIKQLARFASNCGAEIPRWLRIKLESYGDDLPSLRSYGVD
VVSELCETLIEWDVPSLHFYTLNQAGIITRIIQNIEGT
>A0A519TWD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKITDHIKNAQGKTLFSFELLPPVKGKSIDAIYHAIDPLMEFNPPFIDVTYHREDYIYKQ
HESGLLEKISYRKRPGTVAICAAIINKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADANFIPTPGGHSYATELLQQVLDMNSGKYLHDDHDTYKTDFCIGVAGYP
EKHFEAPNLKTDFKYLKKKVDMGAEFIVTQMFFDNAKYVEFVKKCREHDINVPIIPGLKP
ITSAKQLINLPKIFHIDLPDDLSEAVSACKNEAAVKEVGIEFMIAQCKELMKLGAPVLHF
YTMSNPGPTKQIAEAIF
>A0A6A7FQQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hirondellea gigas|TrEMBL
KFEKDCRAAGINCPIIPGIMPIQSYDSLRHIVKLSRLDVPQEILDVVTPLKDNDEAIRNY
GIHHATTLIRELFDNGCAPGVHFYTLNREVASTAILRSLGLWTGAPRRPLPWKMAVNHKR
CAEDVRPIFWASRPKAYVYRTQHWDEFPNGRWGTSESPAFGELKDYYLFYLKSKSSKAEL
LSMWGETLASEEDVWQVFYAYITGGSTEAGPKSKVVTKVPWNDIELSPETTLLRQKLGAY
NLRGVLTINSQPNVNGASSQDPVVGWGMPGGYVYQKAYLEFFTSRENAAALKHVLPLFPR
VNYHIVDKDGSEDFTNCHRHRPLAVTWGVFPGTEIIQPTIVDRVSFKAWKDEAFALWGEE
WGKLYDEGSSSRDIISYIASNYCLVNLVDNNYPEQSCLWDVLEAMFTWKQLNIDNKSCDE
RRNTLCSTALPQCDEVCDEXXCHKEGTSNNPQHGNSVHCCNYSWSRL
>F2NGT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2)|TrEMBL
MNSTTPSRLEKVLAAGHQAVTSEVGPPRNCDGSVIEHKAQMIKDYVDAINVTDNQTSVTR
LCSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAASFGICNILCLTGDHQHFGDHP
NAVNVFDLDSTQLLQTVRMMRDEGHLLGGHQVEPRPQMFIGAAANPFADPFEIRVPRLAK
KAAAGAQFIQTQCIYNMEKFKLWLKLARERGLTEKVAILAGITPMKNVGMARYMKNRVPG
IDVPDEIVKRIGGVPKEKQAEEGIKLAIEQIQELKEEEGVRGFHIMAIEWEEKVPEIVER
AGLYPRPQIN
>A0A168D2A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus glacialis|TrEMBL
MKPDLRQAWENNVLIGDGAMGTFLYQMGFPVGISYEELNLTAPEVIMDVHRRYVEVGAQV
LESNTFSANFDKLSKYGLETKVEEINRAGVRIARDAAGPDGYVLGAVGSIRGGKRTNVST
KRLKIYFEQQIAALLAEGVDGILLESFYDVEELSIALSRVRKLSDLPVICQFAVEDVART
LDGYTMTEALHILQQEGADVIGFNCRTGPNGMMRAVESLGDQLGVPVSVFPNAGVADYVD
GEVRYTATPEYFGTMALRFADLGVRIVGGCCGTTPEHIKEISKALTGYVPNPIDKNRVLA
SPAPRVVYEHTNDNVEDDREPTIVDLVKQRHTVIVELDPPRDLDINKFMLGAEALKKAGC
DALTLADNSLAVTRMSNMALGYLIQDQTGMRPLIHIACRDRNLIGTQSHLMGFDALGIDH
VLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKANFVVGAAFNP
NVKHLDKAVQRLEKKIAAGADYIMTQPVYDPKLISSIKEATAHLDMPIFLGIMPLASGRN
AEYLHNEVPGIQLSEEVRARMVGLEGEEGRAMGVTIAKELIDEAMKHFNGIYIMTPFMFY
GMSVELTEYVWKRSGREVTPLFRS
>A0A7S4DSS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lotharella globosa|TrEMBL
MNGHLQFSEKKNKRDLSDIKGGTSTPRSGPSEKIINKINRAVNERRTFYSFEFFPPKTEA
GVMNLYNRIDRMVAKYEPMFVDVTWGAGGSTAKLTLEISSNVQNYCATDVLMHLTCTNMP
RDSVKDALDKAKEAGIRNILALRGDPPHGQDTWEKCDKGFEHALDLVKFIREEYGEYFGI
AVAGYPEGHISSPNLEEDIKHLKLKVDAGADFIMTQLFYDVDLYIDFVKRCRQAEITVPI
LPGLMPINSYNAFKRMIAYTKATVPKEIIAAIEPIKNNDAMVKAFGIELAKKMSQKILRT
GLTPGLHFYTLNLEKSVTKILGGLGLARLPSKGVRPLPWKQSCATRRRNEDVRPIFWANR
PYSYLSRTISWDEFPNGRWGNSTSPAYGELYDYHLMGLKSSSVRDRLRMWGGEVQSEQDV
FDKFADYIEGKIARLPWCETGIMLETLPLKQRLMAINKTGFLTINSQPRVNGARSDDEVV
GWGDPDGYVYQKAYIEFFASPERIKSLKALASRKEYKTLSYHAVNAKGDQFSNYTDKNAV
NAVTWVTHTTYI
>A0A2K9IXR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Virgibacillus dokdonensis|TrEMBL
MSLLQQLQNQILIADGAMGTMLYSYGIDQSFEQLNITHPNQVQQVHEAYIHAGATVIQTN
TYGANYIKLARYGLEDQVKRINQKAVQIAKEARQKGVSIVGGIGGIHGVQALNETKEEIK
RSFREQLYCLLLEGVDGLILETYYNLDELKMVLEIAREETKIPIIANVSMHVPGILENGT
PLAEALQQLEALGADLVGVNCRFGPSQIITSLQSVPIPKRAFLAAYPNASLPAYRDGVLY
YENEPDYFRECASQLREQGVRLVGGCCGTTPNHIKALAEGLNATNPITEKVVDFPKQDRV
MLKRKRKEKSLAELAKERHTIIVELDAPKHLDMTEYHQGIQALKEAGIDAVTLADNSLAT
PRICNTAIATIIKEQGIKPLVHIACRDRNLIGLQSHLMGLHILGIHEILAITGDPTKIGS
FPGATSVFDVNSFKLIERIKKGNQGMSFSGHSLREHTAFTVGAAFSPNVNNVEKAIARLE
RKIASGADYIMTQPMYSKDKIIALKQATSHIDTPIFIGIMPLTSTKNAEFLHHEVPGIKL
TDEARSRMKAAEGNRAQSTKESIAISKELLDTALEHFYGIYLITPFMRYDMIVELVNYIH
QKTNSMRVKASLSSH
>E6L1J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter butzleri JV22|TrEMBL
MFKTLIQKLQEDKYLTLETTPQHEPSMHNIIEKIKKFNLQDKIDGFSCTDNPLAKLRYNS
LFAALKLQQEFEKPVIATMTMRDRNKIALQSDLLGANDFDVRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGHPFKIEPKQIFPFAVVNSYAKNFSSLEKKMHLKI
QNGAIGIITQPIFDIENAQKLLESFDIAKENVEGDKRKSQLIFGIFPVTKLRTALFLSAQ
VPGIHVPQFWIDALEKAHSIGEEEEYKVGMELSSNLFKELNKLHPKIHLMTANRFDVANE
IIS
>A0A521C1H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter westerhofensis|TrEMBL
MKITEHINNAAGKTLFSFELLPPVKGKSITDIYDAIDPLMEFNPPFIDVTYHREDYIYKQ
HASGLLEKVSYRKRPGTVAICAAIMNRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADSGFIPTPGGHAYATDLLEQVANMNKGKYLFEDHDAFQTDFCIGVAGYP
EKHFEAPNLKTDFKYLKQKVDMGAEFIVTQMFFDNSKYSEFVDQCRANGINVPIIPGLKP
ITSSKQLISLPKIFHLDLPENLTEAVQACKNEKDVKEVGIEWMIEQCKELIQLGAPVLHF
YTMSNPEPTKRIAKAVF
>A0A3E0MJT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa DA14|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGSLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPVHN
>A0A2U2RJU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium endophyticum|TrEMBL
MTAPTTLPELEAAVTARRRPALSYELFPARTDTTFERLRDTIAQLETTAPDYVSVTSRTG
HRNLARVLELTDHVLHETDLRPLVHVTSIGSSRAELRTVIEALLDRGVRGILALRGDQEE
GHDLEDDEIPFARPLVDLVREVERARTAALAGGRMSVGVAAYPHRHPESPTSQHDLEVLL
AKERAGADFAITQVFFDPAEYCALITKAREAGLRMPVIPGFVPATNPRRLERLAELSGVP
LPRDLMHSLETARDEAEQRRVGVRWSVDLIARVLDAGAPGLHLFTFNRHAESLDVLETLD
LDRWSATTTGDDR
>A0A1I6IVS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio sp. NOR37|TrEMBL
MSFEVFPPKKNDEFDNCYNVLDSLAKLNPDFISVTYGAGGSRSKKTVEIASYIQNTLKID
AMAHMTCVGSSEDDILEVTKDLEASGVSHVLALRGDKPRDMSDEQFAKRIFPHATDLIRF
LNTNTNLDVSAACYPEKHPEAMSIDSDLAFMKMKQDMGAKMFISQLFFDNADFYRFVERA
DKAEIHVPIVAGIMPITSAKQIGSTVTLAGSSVPKKLADICAKYGDFPEDMRKAGIEYAI
DQIRDLRKCGMGHIHLYCMNKPKMTEIICKSI
>A0A1M5L0I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cognatiyoonia sediminum|TrEMBL
MTQPAVSFEFFPPKSLKASFRLWECVSTLAPLDPTFVSVTYGAGGTTRKLTHEAVVALRD
QMDLPVAAHLTCVDATRVETDKILDGYAAAGVTDIVALRGDAPKGTNAFTPHPEGFQDSI
ELIETIAKRGTFNITVGAYPEKHPEAASTKADIEFLKRKVDAGATRAITQFFFEAETFFR
FRDACADAGITAPILPGILPVENWAGAKKFAESCGTSIPPLIADAFANAERDGTSDLLAT
ALASELCDDLIQGGVEHLHFYTLNKPELTRDVCHALGVTPKARLQKVA
>A0A401FIV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus curieae|TrEMBL
MNLTELSKQKTVFSLEVFPPKKSTPDSAILDTISKFKTVDPDFISVTLGAGGTNPLDGNI
EVADIIQNQLGIDAVAHVPGLYQSKSDVLNLLDKLNEINVHNILALRGDRITDREPVGDF
NHANELVEFIKANRPEFNILGACYPNCHSDATSFIDDIANLKLKVDSGADHLITQLFFDD
DAFYDFYEKARIAGINVPIEAGIMPCTNKRQIERITSITGVPVPKKFQAILDRYADNKEA
MRDAGIAFAVDQIIDLVSRGVDGIHLYTMNQADTAARIYNETKSVFKATEVH
>A0A1E5W6C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dichanthelium oligosanthes|TrEMBL
MKVIEKIQAAAEDGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVQHIKAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITTALDPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALAILMNL
GLIEESKVSRSLPWRPPTNVFRVKEDVRPIFWANRPKSYIRRTLGWDQYPHGRWGDSRNP
SYGALTDHQFTRPRGRGKKLQEEWAVPLKSVEDISERFTNFCQGKLTSSPWSELDGLQPE
TKIIDEQLVKINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLELFCAKEKLD
QLVEKIKAFPSLTYIAVNKDGESFSNIPVNAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWTRGWACLFPEGDSSRELLEKVQKSYYLVSLVDNDYIQGNLFAAFQEI
>A0A0L0JHR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces acidiscabies|TrEMBL
MTAPHPLFLDASLEMTGKDAPALEGAALAPGTRVNITHLASEDLDTRIDAARAVGKHGLT
PVPHLSARRLRSPAELGETLAALRSAQATESVFVVAGDPTTPHGPYPDALSVIRSGLLEE
HGVRHVGITGYPEGHPAIGTPALWSALEEKTAALKEQSLTATVTTQFGFAVEPVLTWLEE
ARARGIDVPVRIGVPGPAGVRRLVAYARRFGVSTSTGIARKYGFSLTHLMGTAGPDRFLR
ALAADLVPERHGEVALHFYTFGGLEATSAWLTGAAAAPLPARSPRSRASRTTAG
>A0A1F4H9Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFCSPHIGHO2_12_FULL_61_11|TrEMBL
MCGQCVLSATGMACPMNCAKEMRNGPCGGVRANGHCEVKPEMRCVWVEAIEGTKRIAPDH
LDHPTTLLPAIDQRKRGSSSWIHVIHGSPDPALQPPVGERITPEAQQGPLERACRSGRFV
ITVEVAPPDSADPQTLLAKAAPFKGLVDAINITDGAGGNCHMSSVAASAILAAHGFTPVY
QVACRDRNRIAIQGDILGASALGVQNILCLTGDDVSQGDHPQAKPVFDLDAVSLLHIARG
MCDRGEYASGRKLQTPPDLFIGATANPFVPPFGDRIANLEKKVAAGARFIQTQFCFDLAM
LDDFMRRVRERQLHERAHIIVGVGTLSSAKALSWMANHVPGVHVPPALLARIAAAADQKA
EAKQICIETIQALASIEGVAGVHVMGHKNEDVLAEIIAECGLRRQTRLHSV
>A0A8E1W321|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis echigonensis|TrEMBL
MTSVIERLRGDGPAFSVEFFPPRDEADEAVLWKAIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLCPMAHLTAVDHSVSELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPEGLTYAEELVELVRSLGDFCVGVSAFPYGHPRSPDLESDTKHLVRKFRAGADFAIAQ
LFFEAEDFLRLRDRVAAAGCDALVLPGIMPLTTLRTLHTTIKLSGAPASQRLLDRLEPLS
DDPKAFRAAGLDWVTELCEKLIAEGVPDLHFYTFNRSKATREVVTRLGLVPARA
>A0A849ETE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatitalea sp|TrEMBL
MSFQKRLASGEFVVLAEMNTPKGVDISQLITNARRIKGRVDAVVVPDMDNGVMRMSALAG
GVLMQQQGIEAIVHTYGRDRNRMALQGDILAAHVLGIQNLIVAKSEAMANGDHRDAVPVD
DLDELGLLKAIESLEKGVDLAGFDLEGAPSFTTGAVVGSFADQAQMADEIALAKRKIEAG
AQFLITPPVFDVQRFGAFLDQVKGLNVPVIATIFLIKSVGIARYMALNEPGAHISEALIG
RIRKASDREGECLRIAGETISALKDKVAGVKIETQGWEHRLASILDHAGL
>A0A7X3TE46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. SB0668_bin_13|TrEMBL
MKSQVGPSAFQQALASGQPVITAEISPPRGGSVQHVLTTVDRLRGRVHALNVTDGSRAVM
GMSSVAVCRLLLERNLEPVLQMGCRDRNRIALQADLLGAHALGLRNVLCLTGDPVKAGDQ
PGARPVFDYEAVRLLRDVKNLNQGLDALAQPLPDGPTALFPGCAADPQSPSWSGLKRRLQ
RKKEAGAQFIQTQMVTDLAALRRFCRELAAPLGLPVLAGVFLLKSGKNARFINRMVPGAS
IPDAAIARLDAARTPRAEGLRMAAEQVAAVLEIAQGVHLMAIKAESAIPQILDLAGVPPL
APPMVDSVGPRSLAVEPR
>A0A7G7MMM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. CGMCC 4.1532|TrEMBL
MAPPETSSAAELLDRTRDGVLLYGLTPPRATTTADQADAVAEAALTRLRSVQVDGLILYD
VDAEVDRASTPRPFPFLPMMDPADFLDRHLAAWDGPVVVYRAVSKYTGDELGRWLSEVQR
DRVLTVLVGAASRDQAVRTSLPEAYRRHAGLPRPPRMGGVVIAERHADAGAEHRRMLRKQ
DAGCEFFVSQICYDLDRTRNLLSDYAYGCRDLGRAPRPVVLTLAPCGSTKTLEFMSWLGI
SVPDWLRTEITRSADPLAVSYEQCVVNARILIAFCRRLGLPFGINVESLTNRKVEIDASI
DLAREIRSRLG
>A0A6I1Z5H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MSEVKRAFLKALEEEVLLCDGAMGTMLYLKGVFVNRCFDELNLTEPRLIVDIHKEYINAG
AEVIETNTFGSNRYKLEKFGLEQRASEINRLAVEHARAAAGGRSIFVLGSVGPLGRPIVQ
DKGITPVQAHDAFADQVSVLVEAGVDGIIFETISHLGEMAIALEAAREVDPEIPIVGQFA
FADENSILAGASMQEAVNVLEEKGADVVGANCAIGPRTILDVITRMVALTDRPVSVMPNA
GSPEYVDGRLFYFATPDYFGVYAKRFIDAGARLVGGCCGTTPEHTQSMAGAVRALGKGEK
VAVKAQPVEEEDRLEEVPMAERSPLGRKLVEGEFVISVEIDPPRGLGLDKVVEGARALRA
AGVDVINIADGPRATARVNPQSIGLIFEREVGIETILHTTCRDRNLLGLQSDMLGAYTNG
FRNILAVTGDPPLMGDYPSATGVFDVDAIGLVTLLRNLNQGLDMGGRSMKGQTAFVIGVG
ANPAAQNPEREMDRLERKIEYGAEYIMTQPIYDHELLRRFLKSVEHLKRPVLPGILPLAS
YRNAEFLHNEVPGMTIPEAVQERMYKAGDGGAAEGIAI
>A0A2A5X106|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|OM182 bacterium MED-G24|TrEMBL
MNTPVISFEFSAPRDEQARNKVLTVRDKLSELDAAFFSITYGAGGSTRDGTLQTALALAS
TGTNTAPHLSFGGDDEVFIRDLLAQYQAAGIDRIVALRGDVPSGTGPGTHIYADELVTFI
RQESGDHFHIEVAAYPEVHPDSKSPQSDLDYFKQKVDAGADSAITQYFYNADAYFHYVDS
AAALGVDIPIVPGIMPITNVDTLIRFSDKCGADIPRWIKQQLIEYRGDKASLQSFATDLV
TSLCHRLLEGGAPGLHFYTLNQSLPTLRIFRQLSL
>A0A5M6CXK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adhaeribacter rhizoryzae|TrEMBL
MKVTEHIKNASSTLFSFEILPPVKGTSIQSIYDGIDPLMEFKPPFINVTYHREEYVFKER
GNGLLEKISIRKRPGTVGICSAIMNKYKVDAVPHIICGGFTKEETENALIDLNFLGIDNV
LVLRGDSIKTEATFRPHPDGHAYACDLLQHVVSMNHGKYLDEDIANPLPTTFCPGVAGYP
EKHAEAPNLATDLKYLKKKVDMGAEYIITQMFFDNKKYCDFVKACREIGINVPIIPGIKP
LTTKNQLKLLPNLFHIDFPDDLVDAIEGAQTPQAVRQVGIEWAIQQSKELIQFGVPCLHF
YTMSKSDAVVQIAKAVF
>A0A345V8M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. PM3|TrEMBL
MTVHSLSTTSPALRPAGAASALPTRLEIIPTDGIVPGIQASLPAGSTLTVTCLPHHGVKP
TMQTAVQLRRLGYDVVPHLAARSLEDRAQLAGILRDCEDSGITDVFAIGGDAAHAAGPYD
TGARLMEDIADLSGGQIAIGVAGYPEGHPRRNPLHMLDALLEKQHLATHVVTQMCFSAAR
ISCYVELLRREGVALPVWAGVAGQVPRTRLISLATKIGVGPSLRFISRKGPLARRLLNGG
NYSPEGLVSELSAAAPALAGIHLYTFNSLEPYAAAGGPGLAAG
>A0A1E7HHT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium S3730MH12|TrEMBL
MSSFKKSLDSGKFIVTCEVAPPKGINLEKTAHHIDLLKDKVDAMNLTDHQSSVMRYPSLG
GALMVKEMGGEPILQMTCRDRNRLALQGDLLFAASRGINNVLCLTGDSVMLGDHKTAKGV
FDLDSSQLLAAIRILEKGKDLGGNDLDGSPVFCAGAIVTPEANPIEPQLIKFEKKIEAGA
EFIQTQAVYDLVRLKTFMEYARQFPVKILAGILLLTSAPMARFMNKNIAGVNVPQTLIDE
ISQAPKGGAIVKGIEIAGRMIRTIHTEKICDGVHIMAIGKEELVPDIMAAADLTS
>A0A2S9DZM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cedrina|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFSPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A524LDZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichales bacterium|TrEMBL
MKVIEHLAKAKQPLISFELIPPKRGGDIKSLLSVLDDLVKYKPPFIDITSHAAEVIYDET
PAGIQKRIKRKRPGTLGICALIQNKYNVDAVPHVLCQGFTREETEDFLIEIQYLGIENVL
AVRGDRSGYDKPLQHGRTANNFAVDLVKQINDMNKGTYLEENLLDAQASDFCIGVGGYPE
KHFESPNMKTDIMHLKKKIEAGAQYVVTQMFYDNQVYYKFVEACRAEGITIPIIPGLKIL
LSKGNLTTLPRNFYVNIPEILADEIQEADAKHTFEIGVNWAAKQVEDLLAHNVPAIHFYI
MQNSKPINTLMKKLNF
>A0A0Q4ZNT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. Leaf104|TrEMBL
MPSASHHRASRDSYRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVKETSLQPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPQDGIG
TAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEASSLDADIDALKAKVDAGADQ
AITQFFFENDIYLRYVDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLDNDVETRRLVAAAVAAEQVLDLVDHGVNDFHFYSMNRSDLVYAICHVLGLRAQAPKV
AAEAA
>A0A0Q8CWK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Root569|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTHYQQAGIQRIVALRGDLPSGMGMASGELRYANEL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>J2KX52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. CF142|TrEMBL
MTQKNDARRRDIAISFEFFPPKSEEMEGQLWNTVRDLQDWNPEFVSVTYGAGGTTKAPTL
STVTRFLTDTPLATASHLTCVSATKEETHQVVDSFRKAGVTHFVALRGDAPGGVGAPYQP
HPGGYANAAELVAGLKQIGNFEISVSAYPEKHPESRDQAADIEMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGVKIPVVPGIMPIQNLTQLKRFAGACGTVIPDFLDERFAGYDD
KPEERAKVAADVAAEQIEDLVRRGLNEFHLYTMNRAPLVSAVLANLGLSRQTARSAGAAA
>A0A2E1DQW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp|TrEMBL
MKTPRVSFEFFPPKSLEASFRLWDTIQTLAPLGPRFVSVTYGAGGTTRELTREAVGTLHK
ATGLNVAAHLTCVNASRAETLAIADQFHAAGVREIVALRGDAPKGSDGFTPHPQGFANSC
ELIAALAETGKFTIRVGAYPEKHPEAADQKADIDWLKRKIDAGATEAITQFFFEAETFFR
FRDACAAAGIDAPIIPGILPIETWTGARKFALACGTTIPAWLDDAFDKALRDNRHDLLAT
ALCTELCSDLIEGGVEDLHFYTLNRPDLTRDVCHALGVTPRVVLRDVA
>A0A401K6L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia sp. SET104|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRGILNTYRDHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGEAFHIEVAAYPEYHPQSRSPKHDLDNFARKVKAGADSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLESFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A0T5ZFD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon CSP1-1|TrEMBL
MTLRYEINPPKITQNSNLSQEDTLKLLDKVKLRVSEISTRCDGIHFTDSVLGIPRISPIT
TGTLIRKSNQKIEITVSLRVRDKNLTTLRQLMEDAVSGGLNGVLILKGDPSPNEQKDSGL
IPSSTVKYFKELGFDKKIDIFLSLPSNPSFDKIQKKIDAEPTGFITQVIHSADEVSRIVD
KLKPSGFKIIPCVLLPSEKNAKSAKFLKLDWSEYKNSVEDFIKQVHQIAGEVLITSPNDF
NYAKEILGKL
>A0A0E3LQ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina barkeri 227|TrEMBL
MLFNFREKLNSSKFLVTAEVSPPKGTKFSVSLEDARQLKGIADAINVTDNQCSIMHMSSL
AFSKLLLDDGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICVMTGDFPSCGDHPGSKP
VYDLDSVQLLQLIRKLDSGINFAGNQLNGGTSFCTGAVSGIDPEKPLQLIKLEKKVRCGA
DFIQTQAVYDVGMFEEFTEAIGHLEVPVIAGLIPLKSLGMAEFMNKNISGIHVPEEIMLR
IKDAPDPVEEGLSIASETIKELMKLSRGVHIMPIGSHKNTARLLSMAGISGK
>A0A179BWR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MALKNEARGRNDIRVSFEFFPPKSEEMEGQLWHAVSLLQDWDPDFVSVTYGAGGTTKAPT
LSTVTRFLSQTPLATASHLTCVGATKEETHQMVDTFRKAGVTHFVALRGDAPGGAGAPYQ
PHPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQ
FFFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFD
DKPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRRQTKSAGAA
A
>A0JQZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. (strain FB24)|TrEMBL
MMFPTRIEIIPSEGIVEQVKAHVPLTTTLTVTCLPHHGIERTMRAAVQLGVLGYSVIPHL
AARSVPGRSELTGILRDCDVSGINEVFVIGGDRKQPAGPYASSLPLLEDIAQYTGGRMRA
GVAGYPEGHPSVGPVDLLDALLAKQHLASNVVTQMCFSAPKILDFAALLRREGVQLPVWA
GVAGTVPRTKLVSLATQIGVGSSLKFLSRKGPLARKLLSGDRYSPESLVAGLESPAGIFA
GIHLYSFNNLDPAPGGPDQATASAALQSALIRGAARKPDGHSAVRPLSPPAVTSDSSAVS
GE
>A0A7X2GVK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNLIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTF
>A0A7Y2K0Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia aromaticivorans|TrEMBL
METHNFSIEFFPPKTDEGADKLRAVRQKLALLAPKYFSVTFGAGGTTQQGTLQTVLEIKS
EGYEAAPHLSCVGGTRDSLRAILQQFQDAGIRRLVALRGDLPSGYGGAGEFRYANELVEF
IRKETGDWFHIEVAAYPEMHPQARSPQDDLQAFARKIQAGANAAITQYFYNADAYFQFVD
NARKLGLDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRVKLASFGDDSASIKAFGLDV
VTSLCERLLAGGAPGLHFYSMNQAVATTAIWQRLVK
>A0A8H5IN65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium phyllophilum|TrEMBL
MDRITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPTNEWDTLKVKLTSPELQDSVCFYASNARGDYLSSDRSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A6I1GML7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium leontopitheci|TrEMBL
MHKPMFSLEVFPPKRDAPVGTIYDTLDGLEGLKPDFISVTYGHGTHSDRTATARIAATIR
KEYRIPTVAHLTALYSDKERIDQALDLFESAGVSAVLALRGDHLEGETPVGEFEHASDLV
RYIRQRKPELKVFGACYPEGHIEAASLDADIDNLKVKVDAGASHLISQLFYSNDDFYRFL
DKARAAGIDVPIEAGIMPVTSAKSVRSMAQRNKSAIPAPVEAMLERWGDDRESLRVAGIN
YASEQITDLVAHGVDGVHLYTMNRPATTRRIWRNVEPLFTVE
>A0A6P1X3T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. MI 10-1553|TrEMBL
MHRLLKALQNKVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVEHIHRSYIEAGADVIQT
NTYGANFEKLQPFGLEHKVKAIHQAAVAIAKRAAGPDTFILGTVGGFRSTKQGELSLSAI
QYHTDIQVDTLVAEGVDGLLFETYYDDEELLNAIKQTRQKYDIPIIAQLTASNTHYLVNG
KEINSALQQLVEAGADIVGLNCHHGPYHMKRTFGHIELPTNAYLSCYPNASLLDIDQQTF
KYSDNAQYFGETAEQLIQEGVRLIGGCCGTTPDHIRKIKAAVQGLKPIQEKKVIPIHQKQ
TSEAPKQTRQNLATRVRERPTIIVELDTPKHLDTTKFFQNVKALDDAQIDAVTLADNSLA
TVRVSNIAAASLIKQQFNIEPLVHITCRDRNLIGLQSHLLGLSLIGVHEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGVNTDGDTLKVATQFNIAGGFDPHVSNIKAAVRK
METKIKSGMHYFITQPVFTKEKIVEIYEATKHLDVPIFIGIMPITSYKNALFLHHEVPGI
KMSDDVLAQFEAVADDRQATYELSLSLCKSLIDTVHTYFNGLYLITPFERIDYSLELAAY
SKSITTSHQEAIL
>A0A6D1VGQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT1-2-2|TrEMBL
MTAPTPNACDARPAFSFEVYPPKSVAAASALTRTIDHLAAAGPEFISVTYGANGSSRNSS
LDVLRYIKDHTSVDAMAHLTCVGSSHTEASRLIREFLDAGIRSFLAIRGDAPQGADEGDT
TFLGDLHSAGELVQLIHRVQIERVPYIETVIPGLPGARGVKTERSKVRIGVAAFPNGHPN
SRSVTQDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLLPILPGIMPVTSPN
RLRRILQLSGEKLPAELSIQLEVEPTDEGQRQIGIDYAVRLGQDVLAGGAPGLHLYAFNQ
HDTVLKVLEGCGALPVPAAMP
>A0A8H5RXM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sp. NRRL 25303|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIHDIALLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHLVHGWGPDNGYVYQKSYLELLVHPDVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAADTEPIANGTAATAVAN
>A0A7C1HVK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
MMIPFEEYMKDNLVLLDGAMGSLIYQKGVFIDKCYDELNLSRPDLIRSIHEDYVRAGAKV
IETNTYGANRFKLGAHNLAGKLREINLAGVTLAREAAGEVAYVAGSMGPGGVEIEPWGDT
GLEEVFDAYTEQAGILAEGGVDLFILETFQDIREMEQAIRAVRRTGDLPVAAMMTVNEDG
KTRYGVDIGDIAYRLAKSEATLIGLNCTVGPKPMLDFVETLINHSGKPVCIMPNAGRPQY
TDGRMIYMSTPEYFKVYTKRFIEKGVRMMGGCCGTTPEHIRLMADALAMKQTRIQHSLKI
GLRPVTGEPLPEPVSMEKKSRLAARLASGERVVLVEMVPPRSTDISKQIEGARLLLDHRV
DAVNIPDGPRASARMTGLSLAVLIQNQVGIETVIHYTCRDRNLLGMQSDLLGATALGIRN
ILAITGDPPMIGDYPQATAVFDIDSVGLVHLINNLNHGMD
>A0A7L4CWN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eurystomus gularis|TrEMBL
MVNETQHTCSTSSSSKSDAGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSENFLK
FVKDCQAVGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWREDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7C2LSV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
MISFEEYLKDNLVLLDGAMGSLIYQKGVFIDKCYDELNLSRPDLIRSIHEDYVRAGAKVI
ETNTYGANRFKLTPHNLAGKIREINLAGVALAREAAGENTYVAGSMGPGGVGIEPWGETT
LEEVFEAYAEQSAILAEGGVDLFILETFQDIREMEQAIRAVRRASDLPLAAMMTVNEDGK
TRYGVDIDEITYRLAKSEATLIGLNCTVGPKPMLDFVERMKKTSGKPICIMPNAGRPQFT
DGRMIYMSTPEYFGVYAKRFIDQGVRMMGGCCGTTPEHIGKMANTLAMKQTRIQHSLKIG
VKPVTGEPLPEPVPVEKKSRLSGRLASGEQVVLVEMVPPRSTDISKQLEGARLLLDHRVD
AINIPDGPRASARMTGLSLAVLLQNQVGIETVIHYTCRDRNLLGMQSDLLGAAALGIRNI
LAITGDPPMIGDYPQATAVFDIDAIGLVHLINNLNHGMDVGEKRIGEPTSFFTGVGLDPN
SVNQENEIHRLQLKREAGAEFIITQPVFDIPSLESFLEKTDLGGCYLLAGIWPLVSLRNA
EFMKNEVPGVYVPDAVISYIARYDSKEDQLKAGLEIARMMVDTVKTFAHGIQVSAPFGKY
RLAVEVAASMLE
>A0A367JRC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus azygosporus|TrEMBL
MKIIEKIEQAQKNNTINYSFEYFPPKTELGYANLIDRIERMAKLGPEFISCTWGAGGSTH
ERTLELCSTTQSVYGLDTCMHLTCTNMEKDKIDIALKQAKEAGIQNILALRGDPPRGHEY
WTPIDNQFSHAIDLVKYIRQQYGDTFCIGVAGYPEGHVDSPNKEQDMQYLKEKVDAGADF
IVTQFFYDPEAFINWMQNIRHIGITVPVVPCIMPIPTYQSFRRMIHLCNVKVPTEVMKDL
DEIKSDDQKVKDYGVRLAVNIINELHKRANICNFHISTLNLERSTRLILEQLGLIHHKEK
LTANKPSPWAPVHDPIKVEMWDEFPNGRYGDSRSPAYGENTYSLNQILPTSQAILKWGQP
QSEEDVRQLFKRYIQGELDSLPWCEESPQTETGTICQQLIHLIEQGYLTISSQPAVNGAP
SDDKVYGWGPKGGYVYQKAFIEFFISDQAVSELLARLSKDPSVTFYAANRKGDFVTNVTD
PDAQNAVTWGVFPSKEIIQPTIIEKASFESWKEEAFDLWKEWEEQYTPNSPSQKLLKDIG
DRYWLVNVVHHDFQKPDLLFELL
>R5P4M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. CAG:1092|TrEMBL
MDIQKLISERKGEKSFSFEVLPPLKGNGTANLFSTIDKLKDFDPLFINITTHHSEYIYTE
LDNGQFERKRIRRRPGTVAIAAAIQQKYDVPVIPHVICSGATIEDIEYELIDLQFLGIST
LLLLRGDKAKDDRMFTPTPGGHAHTTDLIKQVTQFNEGFFADGTPIKHPGKKFHFGVAAY
PEKHEEAPNIDMDMEYLKMKQDLGAEYAVTQLFYDNKKYFEFVEKARKKGITIPIIPGIK
PFAKLSQITMVPKTFHCDMPQELAQEAVKCKTDEEAKQLGIEWTTAQCQELYNAGISDIH
FYTVSAANSVAEVVRRLHI
>A0A1R4G7L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frigoribacterium sp. JB110|TrEMBL
MTAQAKLIDDFSLEMTGKDVPGLLEAQHAIPQGTRINVTFLGNEDLEMRVAAAKAVKEAG
FVPVPHISARRIGSEAQLREFLAALQEVGASEHVFAVGGDPATPEGPYDSAYDLIRSGVL
PEYGVKEVSISGYPEGHPDISDELLWEHLEKKASSLKEQGLGAVILTQFGFDTEPVENWI
DRVRGLGIDATIRIGTPGPAGIKRLLNFARRFGIGANAMIVKKYGFSLTNLMGTAGPDRF
ITDLADRNAANPASGDVKLHFYTFGGLKATAEWAEKFAAKVA
>A0A420F659|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora globbae|TrEMBL
MALGLPSVLPNSQPAIGELIRERQPTFSFEFFPPKTPEGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWIPHPEGVVYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTRYFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTRMATIERSVQLSGAPF
PRALAERFEKVADDPEAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLR
VDARA
>A0A519RTI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
DSDIHFLKQKIKNGATYIITQMFFDNKKFFDFVAKCRKEGITVPIIPGLKPIATKKQLNL
IPHRFKVDLPDDLIMEVVRATDADAVRQIGIEWCINQSKELMQAGIPVLHYYSMGKAENI
KAIAKAVF
>A0A1F9WFI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFOXYA2_FULL_58_8|TrEMBL
MRITELLNAGRKIFSFEFYPPKTEEDARRLFDSARELKALNPDFVSVTNSSSGATPYRTV
ALSGVLKAELGLETVAHLTCVAHTRAEINDICLRLKAMGIKNILALRGDIHNHEGAPVKR
EYNYAAQLVADLKKSGDFSIGGACYPEKHPEAETLDADIDRLKEKVDAGAEYLITQLFFA
NDFYFRFLDKTAAAGINIPILPGLMPLTGYKQLENLTKLMKVSVPDVVRAGLERWAGDKE
NLFKFSVDYASVQARELLEKGAPGLHLYTLNRSRAAIDILKNVKARV
>A0A4V2FX26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella soli|TrEMBL
MANGLPSTRPGGAPTIRELLASGDRSFSFEFFPPKTPEAEEVLWRSIREIEQLHPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVSHSRDELRSVIGAYAGAGVRNMLALR
GDPPGGPNQPWVAHPEGLNHAVELVELIRSLGDFSVGVAAFPDKHPEATSLEADAQVLAA
KAQAGADYAITQMFFGADDYFRLVDRSAALGCDMPVLPGIMPVTNIKQIQRMAELTGMAL
PEAVTSRLLAVEDEPAAVREAGIEIATELCERLLAGGAPGIHFITLNRSTATRQVFRNLS
STVVS
>A0A3D0ENH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRGIARDYWDSGIRHIVALRGD
LPPGGGKPEMYGSDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAASIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMSAMFE
GLDNDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGISA
>A0A7C3K1X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEKRRFKEALLEGKKFIYTLELVPGRGSRGKTQDEILRLAEQVARTRLAHALSVTDNPGG
HPALSPDVIGLEISRLGIDPIIHFTCKDKNRNQIESILYSLDRIGISNLLLMTGDFPLYG
FEGEAKPVYDLDSVQLLRFINKMNEGLEIDGKAPGGGIRLPPTHFFKGCTVSPFKKYESE
VMAQYYRLHKKVKMGADFIITQLGFDARKFDELIRVMRLSGLAIPVLGNVYVLNQAVAKV
MNRGGVPGCIVTDDLYQIYEEEAKRPDKGKKAGLIRASKLVAILKGLGYHGTHVGGPNLK
FEDVEEVIERSEEFYPNWRDYVREFSFPQKDGFYLFEKDAKTGLNTDRYASRGSRPRKSL
GYAVMRFFHHLAFTPEAPLFKPARGFFEKIDGTWLEGLVTELEYWIKFISSRCRRCGDCT
LLEVAFLCPQSQCPKYLFNGQCGGSTEGWCEVFPGKRKCIYVRAYNRLKPYGEEESLGKG
YTRPRNWALDQTSSWANYFLGRDHHGEK
>A0A7C5D8W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MFEKFCDVLCLEKEFITVEINPPHGASIDGLIADIQKHKLQDKVTGFSCTDNPLAKLKMS
GVLSAIKVQQTFGKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKFSDQPD
VKGVLERDSTLLLSIIHHLNKGVDYSNKPLSPAPKPIYPFAVTNSYAKNMDSLKKRMVKK
LNYGARAIITQPVYDIDNAKELLSLFEEAKAESIRDTAKEAHLVLGQFPIVAARTANFID
DKVPGINVPKPIIDEMNLAAMDGSDKEREVGFALSKRIFDDVMKEHGKVHLMTHNRFDLC
AELID
>A0A7V0Z154|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGLEESLKSKRFVVTSEVQPPIGTGIQDLVRNIEKIRGRIDALTVPELKIEGLVTDTLGT
CRALKEQKFDPILQTTCREKSRVDIQEHLLKASESGIENILTFTEDYRITGDSLQEIMFF
HVDSGKLFSVIENLREGHDISGREIPGKPKFCIGAGIEAGWGKKVPDLELKEMEALAGMG
THYFLTTPVFDLDAFNQFMKRVGPLRVPVIAEIILVRSAEMGLFLNKHVRPGMVPNHIIE
KLAKAPDKEKASIEIVRDLVQGLKDLCQGVHFIPIGAEDRISKYLDALRL
>A0A7Y1YCA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MALKRKVNISARGKAALTALLSDMTYELIPLSNVLPQSGFLPEGARVSVTASPAKGMQAT
VDLALELQQRGFDVIPHISARLTQDRAELESIMKQINDAAIKKAFVVGGDADPPGDFFDG
LAVLHAMEEIGHDLTIGIPSYPEGHNFISDDAINQALLDKQPYAASMTTQMCFKPQTIAD
WIGDQRARGVELPVKIGIPGVAELRKLIGISARIGVGDSLKFLTKNTSLVGKLVRPGGYS
PDDLLIGLSSVFADDYSNVVDLHCYTFNQVESTEEWRHKMLASLD
>A0A7V7D9N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTDVKTPSKLEKILAAGHLAVTSECGPPRGSDPEVITKKAEMIKDHVDAINITDNQTSVT
RMCSLASCIHLKQMGLEPVLQMVTRDRNRIALQSDILGAASFDIYNILCLSGDHQSFGDC
PQGQNVHDIDSMQLIQTVRHMRDEGKFLGGDDIKRPPQMFVGAAANPFADPFEIRVPRLA
KKIAAGVEFIQTQCIYNLDKFEKWMELARDRGLHEKVYILAGLTPLKSAGMAKYMKNRVP
GMDVPDDVVKRMADTPKEKQSEEGIKICIESILRLKEVQGVAGFHIMAIEWEEKVPGIVE
ETGLYPRPTLE
>A0A7L6UA21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. RHB35-C21|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIAQDYWHNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A6L8GYP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MAGSPRRRRLAGESPEHRAARAAVIEASSFEVIPLRSLDAAVEALPCGSRVSVTASPAKG
LAATQEITEQLIAAGHAAIPHISARLVRDRTHTRALAAWLRSTQTEEIFLVGGDVAEPGR
YPDALSFLGDLLEAGPGLRRVGVTAYPDGHPLIDPATLDSALTDKQAMLAEAGLAGYSST
QMCFDPERIAGWLRRQRRQGMDLPVHLGIAGVVDRAKLLSIGLRLGIGQSLRYLRKNRRA
VTRLLTVPHYDPNDLLVPLSPHLVELDIRALHIFTFNQVAATAAWREQNLR
>A0A809SPL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia rettgeri|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSEEMEQTLWKSIDRLKNLKPQFVSVTY
GANSGERDRTHSIIKDIKDKTGLIAAPHLTCIDASPDELKDIARDYWNNGIRHIVALRGD
LPDNSRKPDMYAVDLVELLKSEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPAWMSKMYE
GLDDDLESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A8D2NUX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zosterops lateralis melanops|TrEMBL
MVNETQQTSSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKXDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWREDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDELERVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYEQRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLNSATQQ
>A0A7Y2P974|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEEILDRMKKSPIVFDGAMGTMIYERGVFINTCFDEVCLTNPKLISQIHSEYIEAGAEVI
ETNTFGANRIALRPYGLSERVKEINRQAVRIAREVAGDQVYVAGAVGPCLRPDQIMPDDH
TVEVEEAFVEQIGALVAEGIDLVVLETFTHLKELQLGARTARRLGTPVLASFVLNDRGET
AMGMQAAALAWALDADENVDAIGINCGTGPAGIFDALQSVLPQVSRPVIVMPNAGFPRDV
GGRLLYLTSPEYFTEYAKKYIELGVRGVGGCCGTTPAHIRVASRAIKSLSGVKKHVEVRP
VAQQGVLIQVIPPERKSKLARNLVEGKKVTSVEIPPPRSSDLSGMLAKVRKCAEAGVDAI
NIPDGPRASARISPMIAAITILSEVGIEPILHYCCRDRNLIGMQSDLLGGFAAGLANFLI
ITGDPPKVGDYPQATGVFDVDAIGLTQVAANLNRGFDIGGNPIDPPTAIFLGVGANPCAV
EMEREIDRYFRKIDAGAEFATTQPVFDVEALFRFLDRVEGYERRIPVIAGVWPLVSYKNA
EFMNNEVPGVVVPREILDRMYRCRTKEEARRAGIDIARKTIEQVSSRVSGFQVSAPLGSV
EIALDVLKKGR
>A0A7V9IHE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MGDSMSSLFRRRSTGPTVAARSRPAPDAALVRLLTATRFELVPIRSVDAAMTELPAGIAT
SVTCSPVKGLGATLDVTARLLDTGHDAVPHVAARLIEDRQHVARLAAWIRSHGLREIFVV
GGDQLVPSGPYADGLALLRDLFEHDTCLASVGVAAYPDGHPAIPDDVLRTALHDKQRLIE
AAGLAGWATTQMCFDPDRIRRWLLAERAAGFALPVDLGVPGVVDRTKLMSMGVRLGIGSS
LRFLRKQRATMTAMLAPGGYDPTDLATAIAANASALRIEGVHSFTFNSVARTEVWRRSII
DRA
>A0A7C8B0P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLVEKNSPFRKSLFNPEQFTITLELVPSRGGHSREHERTLELAEKLAHDPRIQAVSITEN
AGGQAALSPEVLGREIQEMGLDVIVHFSSKDKNRNQMESLLFAWDRLGIRDLLVITGDYP
QEGYQGFAKPVFDLDSVHVLDLISRMNRGNYGPDRGRGGIRPTSFLMGVALSPFKKLEAE
LLMQYAKLHRKAERGADYIITQVGYDARKFHEVILYLRQNGLNLPVLGNVFVPNLTVATL
MHTGKIPGCIITDALYAEIRREATSQDKGKQSRLLRSAKLLAILKGLGYAGAHLGGPGLT
YDNIDFLLTTADSFAENWQELIPEMNYWHPNGFYLYKKDEQTGLNTCEPAPCKEKTAGLQ
INYRMARLVHNLAFEQKAPLYPLCKKICLALEGGGLDNTLTHLEHVTKFLLFGCQNCGDC
ALGELAFVCPQTGCAKYLLNGPCGGSRDGWCEVYPGKKRCLYVRIHERLAAHDLPESMGQ
GFVPPRNWALNNTSSWLNFFRGWIMPEETGQPKSDRTPARPKNPEFSSLPIKTQLPGSGA
AAGQLMWCRRTAAYEKNISHPYKRMYIFSFFPCEQKHIMRDNSP
>A0A8B4GDM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eikenella corrodens|TrEMBL
MLHNTLSFEFFPTRTPEGREKQKITRKQLSQYQPEFFSCTSGAGGTTREGTMQTIRDILA
EGMAAAPHIPCVGLDAGELTDLLQEYKDLGIRHVVALRGDIPSGMGLGTTGLHHANELVE
LIRHRFGDWFHIEVAAYPEYHPQSRSAEDDIQSFVRKVKAGADSAITQFFFNADAYFRFL
DDVRGRGVEIPIVPGIMPIANFSKLARFADMCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCGRLLRHGAPGLHFYTLNQAGLSSTICQRLGY
>A0A4P2VTF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fluviispira sanaruensis|TrEMBL
MTDHRNKTPQRCCRSFRKSLSDGDCVLLGGSTGSLLYEKGIFINRSFDEVNLSQPDLVSK
IHSDFIAAGAQIIGTNTWGANSFKLKAFGLENKFREINFAGAELARKAALNQTWVAGTLG
PLGVRIEPWGPTSLDEARDVFKAQAEALIKGGVDLFIMESFADLYEIQQAIRAVRELGDL
PIIAMMSVNEEGHSLYGTEPEWYIRKLDEWGADVVGADGGNGPTPMLELLKKFKSSTKKP
IILCPNAGQPRMVDGRLIYMASPEYMGEFARQAFLKGARLLGGSSGTSPAHIKIMAGALR
QAKAFDQVEIKPHEIIEHTLVHPTTVPRVQQSNWAKKIADGEFVVCMELLPPKGLETEKI
IERSEICKKHGIDAINIPDGPRASARMSSLATACIIEREVGIESILHYACRDRNLLGIQS
DLLGASGLGIKNILCITGDPPKMGPYPNATAVFDIDAIGLVNMVTRLNTGYDLGGSSIGR
HTSMSVGVGANPVAIDLEKEKSRFRYKVEAGAEWAITQPVFDSESLFRFLEFSSQFRIPI
IAGIWPLKSIRNAEFMANEVPGVFIPNNVLERMRKCKTAEEQTQEGILIARELIEEIKSS
VQGLQISAPLGMVDFALKLL
>A0A6P0UCN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muriicola jejuensis|TrEMBL
MKVTEHIANAKGETLFSFEIIPPIKGRSIQELYDNIDPLMEFKPPFVDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIMHKYDLDAIPHVLCGGFTREETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFEPTPGGHQYASDLVRQIRNLNSGQYLHEVIETDSCSDFCIGVAGYP
EKHMEAPSIKTDLKWLKKKVDLGAHYIVTQMFFDNRKFFDFVAAAREIGIDVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVEKCRDNKAVRQVGIEWAIAQSNELKKAGVPVLHY
YSMGKSDNIREIARALF
>A0A660QE94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotogae bacterium|TrEMBL
MKVIEKIKKEQILSIEILPPNRGEDMNQIFSVVENLMDFSPSFVNVTRHAPEATYVELNG
HIKKVPKLKRPGSVGVTAALMNRYNIDVVPHILCTDMNKYQIEDTLIDLHFIGVQNLFVI
RGECENRTVSHVGKDMHSHASELVEQISNMNKGKYLYPCENPRPTDFCIGVAGYPEKHFE
SPNLQEDIRYLKKKIDAGADYVITQMVFDFDVYKRFSEIARESGVLVPIIPGIKPIMNL
>A0A509LD17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSLKQKLVAGKFAVLVEMEPPKGVDVSVMVANAQKVKGIVNAFVVPEMRNAVMRMSSLGS
GMILQSKGMDVVIQVNCRDRNRLALQADLLAANGCGIHNLMVVRGEDPGFGDHHQARAVH
DIDLTELLKVIQGLQNGRDMAGIELNGAPTFLVGATVDAGARDKSPELIREEMDQKREAG
AEFFITPPLFDLSTIEPFLKRVDRSETKIIPTVLLLKSLGMARYISRNVSQMFIPDALIQ
RLQKAPDKVSECIKIASEMVQTLKKEGFCGVQLSTIGWEDKLPAILKGV
>A0A1H5R974|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis pretoriensis|TrEMBL
MIERLRGDGPKFSIEFFPPRDAADEAVLWKAIRELEPYDPAYMSITYGAGGSSRDGTIRS
IARVATETTLVPMAHLTAVNHSVAELRNVIGWYASVGVRNVLALRGDPPGDVYGDWIPHP
DGLTYAEELVQLVRELGDFCVGVSASTYGHPRSPDLESDTKYLVRKLRAGADFAIAQLFH
DAEDFLRLRDRVAATGCDVPVLPGVMPLTTMRTLQTTIKLSGAPAPRKLLDRLEPLADDP
KAFRAAGIDVITELCEKLIAEGVPNLHFYTFNRSKATREVIARLGLVPARA
>A0A354FI71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSRHRKHQPSPLYRLRHETPMKLIDLYRRKSFVFSIEVFPAKTAEGMETLKQTLGTFAKF
RPDYFSVTYGAGGGTRENTHALATHLQNKLGIETMAHLTCVSHTGQEIEVVLRQLEKSGI
ENVMALRGDPPQGSTEFRRPENAYNYACELVAAIQKRGGFGIGAAGYPEGHIENPDQDAD
RHFLVGKINAGADFIATQFFLDNSFFLRWRDQLAADGVSVPLVPGLLVPTSLKQLTRMAD
FCGISIPNKLRIQLETHHTDPEAMKQIGLEHTSRQLENLLREGIPGIHLYALNKLATVQH
LAPLLPYSSKNLLAPCAA
>A0A4Q9QLX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas daroniae|TrEMBL
MTQKKTNVSFEFFPTKTDAGHEKLLNTARELAGYNPDFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDSKAELIELLNLYKSKGITRIVALRGDLPSGMGMSSGELRHAND
LVELIRHETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGASSAITQYFFNADCYF
YFVERVRKLGVDIPVIPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDTDSIQRF
GEEMITGMCERLLEGGAPGLHFYTLNQAAPSLAVWKNLQG
>A0A135I4V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterovibrio coralii|TrEMBL
MLLDKIKARESGIILYGLVPPKKGTESEKVTEIASRQVARLQDQPIDGLIVYDIQDEATR
TSEERPFPFMETLDGVEYSRDYLADIKLPRVIYRSVGKYSEASLSRFLEDSHPADELSVF
VGASSADQSVTMPMSEAYALKKRVNKDMLLGGVTIPERHLVKGDEHLRVFRKIEAGCSFF
VSQGVYDVHASKDFLSDYYYYGKKHGIPLVPIIFTLTPCGSQKTLQFMKWLGINIPRWLE
NDLIHSDDILQQSVDYSEQSWRELKEFADEKGIPIGCNIESVAVRKVEVDASIELLNRIK
AI
>A0A661J2T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MIKKITDIFAEKMKIGDPVFSFEVFPPKTSEGIENLFGTIEELVELEPDYISVTYGAGGS
TTRSTLDIAKKIQDRFGITCMHHFTLVNQTVEELSRHIELMKDAGVRNVLALRGDPPTEM
GEKFKKIEGGLEYCYELIDLLKEVGDDSFSIGVAGFPECHIDCPVEDLDSAYLKMKVDHG
AEFVITQLFFDNPSYSHYLERVSAAGVGIPIIPGVLPIMDYQKLLRFCDTCGAYICREVH
KIFAPVAHDLEETVKRGTRYAIEQSGDLLRRGAPGIHFYCLNKTEPIRTIWQQLKDRAGE
FVPKQAAI
>A0A534QIN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKITDILARGGPCISFEFFPPKTPEGEAALMRTIEALKPLGPGFVSVTRTGAKPREAPVE
LVTRIRALGIEAAAHVTCIEASRDELAAHYDLIQARGIENVVAIRGDRPSDPQFRQPPDG
FRYAVDMIRYVRARGHELCLVGGGHPEGHPDCRDLELNIRHLQMKVDAGLDAVITQLFYD
NADYFAFVERARRAGIGVPLIPGIMPITNVPQIERITALSGNQIPAALRVALERARDDED
AALDVGVEWATRQCAELLRSGAPGIHFYTLNKSPATRAIFENLGAEGLVGTPAPRLATPS
AIR
>A0A661PCW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSNLEKVLTAGHFAFTGEVGPPRGANGEVIREKAKFLKGNVDMANMTDNQTAMVRMS
SWAGSLILLEEGVEPNYQMVCRDRNRIAMQSDILGAYALGIRNILCLSGDHQQFGDHPKT
KGVYDVDSIQLISIVKKMRDEGKFLGGDDLNGAPKMFIGAAANPFGEPFEWRVHRLAKKV
AAGADFIQTQCVFNMERMREWVHQANEMGLTEKIYILPGVTPMKSVGMAKYMKNNVPGMD
VPDEIITRLQGVEKKKAADEGIKIACEQIEEFKEMKGIAGVHLMPIEWEHRVPEIAERAN
MLPRPQV
>A0A2E1A159|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MIAAALSVPDPFLHEAVAPCTDWSLEILPKHAEAVRDLPDYIREIYVTVIPETPWAEVVA
AVRTVHELGRSPIPHITARSIPDKNALEQLLLQFKEFGVERALLIGGGIPEPAGEFTSVL
ELLQSGLFEQHGLRDLDLAGHPEGNPDDPHAEQSLLDKLTWGRERGYRFRIVTQWCFDAD
AVNKWIARLRELGVTEPIHIGVPGPATMKTLMRFASLCGVKASATVLRKQGLHLTKLLFV
NKPDKLVDALRGHDQLHLFPFGGMDKASVWLXAWHRTHA
>A0A3D6DCR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotogae bacterium|TrEMBL
MIYTKSISEKRTYSKWGEQDLAVLKDHIEKKKALVIETLPPRGPDPKKYLDYVRSVWKIG
VSAIAVTDMPLARIRVSPWAVSTLMIQEGMEVLPHFSRITRNKCRVESDLLGFHILGVRN
LLLLSGDDPNHGDYPDSSVVQDMSIYELIKLVKLMNTGTDLAGNKLNASTEFYVGAVFSH
SFDEEIERVERKVKAGADFLISQPVFEKEKLQRFLDRLTVVPPVLVSTVVFKNRSQLSHF
ASVPGIVLPKEFIDLLEEDRSDEYIKHYTTDYILKVVDEIHPYVSGIYVAGIVRDLSFMS
QLSQLLASEEY
>A0A423WRI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Valsa malicola|TrEMBL
MEKITDKIAAMPPDANYFSLEFFPPKTQMGFANLRSRLERMARALKPTFVNITWGAGGST
SQKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALEDAKVLGIRNILALRGDPPRRAE
YMDENDEDDDLGDDEFKWAVDLVKYIRKNHGDYFCIGVAAYPEGHADESHPLGQSMEHDL
PSLVEKVQAGADFIMTQLFFDIKAYDKFERTLREHPTGAFKDIIIVPGLMPIQNYQMIKR
TTKLSHAGIPDDLMARLDEVKRDDERVKLVGVDILSELIEQIREIKSRTPGPKGFHFYTL
NLEKAVSFILERTGLIPPESPAGEQALAVDDLIPTVPKVEINGTSSNGTGSTSQQHLGVS
SASRRQSTVSSEPRNRVIVSGERTPSNPEYEATQLEASRPYEPVHSRANTLAISEGEGVL
GREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSVTAARSLWGAPSSVETINNLFIRHL
QGDLRAIPWSEAEFNDETGVIKDQLIALNQKGWWTVASQPAVNGVKSTDPTFGWGPANGF
VFQKAFVEFFLPADQWKRLHEKIARPEMKESIWFYAANAAGDFVSQDFSAEPDQDMQEIG
TNAVTWGVFPGKEIVTPTIVEEVSFRAWAEEAFGIWGEWAQVYGKGSEAAQFLEKMKGDL
WLVNIIHHEYVEKDALWDFLKSA
>A0A496Y8D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTTKTPSKLEKILAAGHLAVTSECGPPRGSDGEAIAKKAEMIKDHVDAINITDNQTSVTR
LCSLAACIRLKLMGLEAVLQMVVRDRNRIALQSDILGAASFDINNILCLSGDHQVFGDNS
RGQNVFDIDSMQLIQTVRYMRDEGKFLGGDEIKRPPRMFVGAAANPFADPFDIRVPRLAK
KIAAGAEFIQTQCIYNLDKFELWLKQAGDRGLLDKVAVLAGLTPLKSAGMAKYMKNRVPG
MDVPDDVVKRISGVPKEKQADEGIKICIESIQRLKEVEGVKGFHIMAIEWEEKVPEIVEQ
GGLYPRPEVEE
>A0A661QXD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MHLKRKFDTEGFAVLAEMEPPKGVDISGMITHAMRVKGKVDAFVVPEMSNAVMRMSALGG
AMILQAKGMDTVMQVNCRDRNRIALQADLLAAYGCGITNVMAVTGEDPSFGDHFKARSVY
DIDLLELLRTIRGLEQGKDMAGIELSGSPEFLVGSTVDAGAKGKSIELEIEEMKKKIEAG
AQFFISPPLFDLSAIHPFMKRMEQNKIKIIPTVLLLKSLGMARYIMRNVEDVYIPDTLID
RIHKSSDKVRECTLIASEMVASLKKEGFSGVNIATIGWEHKLPEILDNVHP
>A0A661JSB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
LKGVVDAVNVTDCQTSVVRMSSLSSCLILKEMGFDPILQMVTRDRNRIAIQSDILGAAAL
GINNILCLSGDHQRFGDHPQAKNVYDLDSIQLIMTVKKMRDEGKFLSGEELTKPPRLFIG
AAANPFADPFEIRALRLAKKVAAGAQFIQTQCIYNLKRFEEWMKQVVDMGLHEKVYILAG
VTPMKSVGMARYMQKMVPGMDVPEEIITRLKGVPKEKQPEEGIKICIEQIERLKEMEGIR
GVHIMAIEWEEKVREIAEGAGLLPRPDV
>G5QSI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Rubislaw str. A4-653|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A496Y0J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTESKLEKILESGQLAVTSEAGPPRGAEPEVIRKKGEMLKAYVDCCNVTDNQTAMVRVC
SLASCIILKQMGLSPILQMTARDRNRLAIQADILGAYAFGINTMLCLTGDHQSFGDHPTA
ANVFDLDSIQMIQGVNKIRQEGTFMGGAKMTLAPKMFIGAAANPFADPFELRVMRLAKKI
AAGVDFIQTQCIFNMDKFGKWMQMICDEGLDQKVHILAGITPMKGLGMARYMKNKVPGMD
VPDEVINRLKGVPKEKQADEGITMAVEQIQQLKEMKGVHGFHIMAIEWEEKVPEIVERAG
LLPRPKVD
>A0A2N7R5R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. AD21|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A496Z426|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSFREALESGKFLVTAEVGPGKGTDVEHLLKDADIIKDRVHAINVTDLQSSVMRLGSMAV
CHLLTDRGIDPIFQVTCRDRNRLALQSDLLSAWVLGIRNVLALTGDHPTLGDHPQAKPVF
ELDSVTLLEVIGKLNSGFDMAGHELKGAPDILPGAVVNPGADNEAALDLQIMKMEKKIEA
GAKFFQTQGVYDLDAFEKFMKRIEGFHTKVFGGIILLKSVGMARYMNKNVAGVFVPEPLI
QELKEAEDKAQASMNIAVRLIKGMKDLCQGVHIMALGWESKIPPILDEVGL
>A0A2D4TQJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MQDFDKYIEQDFIQKIIQLSNRCMSDKIPNWSLEILPHHVSEVQGLPQWVEEIYVTMIPG
SKISEVVEASAQLVDEGRTPIPHIAARGMESREQFSEMLESLKQKGVNRLLLIGGGEEEQ
QGPFTEVMDLMETGELQRIGFEEIGIAGHPEGNPSDPDAENSLLKKTRWATKQGISTRIV
TQWCFESQTLNRWINNLHEQGVTNPIHIGIPGPATLKTLLRYAQVCGVKASSEVLKKQGF
NLGKLLFVNKPDRLVQEIRGHQQLHLFPFGGLTKSSEWLQQQRNLASAA
>A0A838QL33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MKTLADLIADGRVHVVDGAMGTMLYGRGMFLNVCYDELNLKQPGVVRDIHREYVRAGAEL
IETNTFGANPVKLATCGLADETERINTVAAELAREAAGGRAAVVGAVGPLGIRIEPFGEM
SVGEARAAFSRQIQGLLDGGVSGFVLETFSDVAEIRAALEAVRSLCDLPVIAQMTVGTDG
KTHYGTDPEVFGPELEAMGADVIGVNCSVGPHGVLEAIEKLARVTTRPLSAQPNAGLPRE
VGDRKIYMASPEYMASYARRMVETGARFVGGCCGTIPEHIKAIVGFVQSVSPRHVHAPTA
VPQPVATAVEPVPLARRSRLGTKLATGQFVTTVEIVPPKGVDPGPMFDQVRLLKAAGVDA
VNVPDGPRAQSRMGALLSALMIEREVGLEAVVHYACRDRNLLGMLSDLLGASAAGIHNLL
IITGDPPKMGPYPEATAVFDIDSIGLTNLVSRLNRGLDPGGNPLGQPTSFVVGVGVNPAA
PDLERELRRFAWKVDAGAEFAVTQPIFDLDQLDRFMARVEPFGIPILAGIWPLVSLRNAE
FLANEVPGVSVPDSVLDRMRQASARGKEEALAEGVRISQEMLAAVAERVQGVQVAAPLGR
VPVALEVLEAAHIEPVTSQSYTPES
>A0A8D9RBF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia mallei FMH|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A7V8JN83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MQAQSLVRGSSLEVGARDIPALRAVAARIAPGTTISIPYLPREDDAARLAAAAAVHALGF
EPMPHLSARRIGSLAALQDFVQRAAGEAGVTRCFVIAGDPDTPLGPFTDSMALIETGLLE
GAGLQQVGVGGHPDGHPVMDAAQRWAALQQKCDSITQRGMAPLIITQFAFDAEAVLAWVD
ALRARGIGHPVRIGVPGPASIALLARYAALCGVSASAAMLARYGVSLGRLLGSAGPDLFV
DRMAAGLGDAQGAVGLHFFPFGGIARALEWRDRYCAAQR
>A0A0C9V1Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerobolus stellatus (strain SS14)|TrEMBL
ENRSRPFYTFEFFPPKTDQGFSNLLGRIERMAVFNPLAISVTWGASGSTKDRSLELAGLT
QAEYGIETILHLTCTNTEGGMIDEALKGAKAHGIQNILALRGDPPRGAEYWIPTDPRFVH
AKDLVAYIRSEPEYAEQFCVGVAGYPDGHPDHDVDEETELENLKAKVDAGADYIVTQLFY
DVDGFLDWVRKVRAKGIQVPIIPGIMPIQSYASFLRVTKLCGTRIPSEIIAALDPIKHDD
QKIKDYGIELCINMIRRLYQEGHIQGYHFCTLNLEKSVRKVLEGLQWIGDGQKPAENKL
>A0A6N2ZR54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYTVDQIVDLVTQDVAGIHLYTMNNAEVAHQVHQATEALFHHKTKLEVS
>A0A7X0QYB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter sp. Tf4|TrEMBL
MKVTDHFKNANGKTLFTFEILPPLKGENMKTLFSHIDPLMEFKPPFIDVTYHREEYVYKQ
RENGLLEKITTRKRPGTVGICAAIQNNYKVDTVPHLICGGFNKEETENALIDLHFLGIDN
VLVLRGDCVKSEQRFVAEPGGHNYATELIEQVVNMNNGVYLDDEQAYHNGTGFCIGVAGY
PEKHFEAPNLKSDLRWLKKKIELGADYIVTQMFFDNQKYFDFVNRCRAEGITVPIIPGLK
PMTTKTQLTLLPSLFHIEVPCELADAIEDCPDNKAAAQVGVEWAIKQSKELMEFGVPCLH
YYSMGKSDSVRKVAEALF
>A0A1E3QHM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Babjeviella inositovora NRRL Y-12698|TrEMBL
MKISEKLQQAHKKLLNTSNPEPTKPTFSFEFFVPKTSQGVQNLYDRMDRMYDLNPQFIDI
TWNAGGRLSTLTNEMVATAQLVLGLETCMHLTCTNMPVSFIDTALQSAYDAGCQNILALR
GDPPVDGSESTGDFQYATDLIKHIRKHYGDYFNIGVAAYPEGHPEDDDVDLLITYLKQKY
DCGASFIVTQMFYDVEKFIAWCANVRAAGIDIPIIPGIMPISTWGSFMRRAKWCEINIPD
YFLEQLEPIQDDDQAVREVGTDLVAEMCRKMVDSGYVNHLHFYTMNLEKATTMVLEKLNL
LGPPSLESTPQPESAVSTPSTTNKLPWRKSLNPNRTNETIRPIFWQNRKHSYVIRTANWD
EFPNGRWGDSRSPAFGDVDFHSGQTLLRQTSAKALEMWGLPQSPADLAEVFVDYLNGGIP
SFPWSDGALSNEINIIRPQLVAMNRKGVFSVNSQPSVNGAPSNNSIFGWGPANGFVYQKQ
YLEFFIHKDHLASVIGKIRAANGDDEDAGFNVLTYYAVNVEGELQTNAKEDEIHAVTWGI
FPGQEVVQPTIVEQTSFLAWKDEAFQIVNEWANALKLEKRKQLKKMDSETEGDEAVDLDR
FDTSVQLLDQFQKDYVLCNVVDHDFVHGNDRIFSLFSDIQ
>A0A6I1PFF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter hepaticus|TrEMBL
MCSFSFEIFPPRKDESIKNLNTILDDLGQLSPNFISVTFGAGGSVNSKNTLETATLIQDQ
YKFPSIVHLPCIHANKDKITTILKQCKERKLEKILALRGDVCNSVEKSKDFSYASDLISF
IQEEGGFEIYAACYPEKHNEAKNFIEDIHHLKIKVNSGTNKLITQLFYDNETFYTFKQNC
ALANINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFTKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELCVEKQS
>A0A7C1HAM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioalkalivibrio sp|TrEMBL
RDTGDFSYANELVAFIREETGDHFHIEVAAYPEFHPQAPSADVDLQNFQRKVEAGADSAI
TQYFYNADAYFRFVDDCDRLGIDIPVVPGIMPITNYTQLARFSDACGAEIPRWIRKRLEA
FGDDKAALREFGEEVVTDLCQTLLDGGAPGLHFYTMNQSGPTLAIWRNLAGR
>A0A6H2F526|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae endosymbiont of Plateumaris rustica|TrEMBL
MKYFYIEKKEYIDKFFNKSFNECKISFEIFPPSDYEKKSKFWNLIKTLVILKPKFISITY
RNINNYYNNRTYNIIKKIQKYTNIELVPHMTCINLKNNELYDIAIKYWNNGIKHIIALRG
DKTEFNKNINSLIYASDLVYFLKQIANFNISVAAYPEVHPESRNAKEDLINLKRKVDAGA
TKAITQFFFNIEAYLKFRDKCISQGINIEIIPGILPITDFIQLKKFIKITNIKIPNYINN
MFKNLNKQDKNICKLLGSFIAIEMIKRLKNEGVNHFHFYTLNKLEIIYAICLYLGIEPNK
NIFKE
>A0A524HNU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MTTLRDLLDDGRTHVLDGAMGTILYSRGVFLNVCYDELVLRQPDLIRDIHREYVKAGAEA
IETNTFGANPIKLAHYGLADETGAINRTAAQLARDAAGPKAAVLGAIGPLGIRIEPFGEM
SADEAEAAFGAQVEGLVAGGVDGFIIETFSDVEEVRAAIAAIRAHSDLPLIAQMTVGTDG
KTYYGTEPATFGPLLEAMGADVVGVNCSVGPHGVLEAVEALVRVVTVPISAQPNAGLPRE
VGDRKIYMASTEYMADYARRIVEAGARFIGGCCGTTPEHIKAMVAYVKSVRPRHSASIMV
VPELAQPTPAVPLAERSRLGAKLAQGAFVTTVEIVPPKGVDPAPMLAQARTLQAAGVDAL
NVPDGPRAQSRMGALLSGLLIQREVGIEAVVHYACRDRNLLGMLSDLLGAAASGVRNLLI
VTGDPPKMGPYPDATAVFDIDSIGLTNLVHRLNQGLDPGGNAIGAPSQFVIGVGVNPAAV
DLDRELRRYAWKVDAGAEFAVTQPVFDLDQLDRFLSRVESFRIPVIAGLWPLVSLRNAEF
LANEVPGVSVPQAVLDRMRAASARGKEAGLMEGVAIAREMLAAVRERVQGAQVAAPLGRA
DVAVNVVRP
>A0A7U8PFZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella abortus bv. 6 str. 870|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGGAAGA
>A0A6P1Q8K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter pasteurianus|TrEMBL
MSLSRLSVELIPRSAEALAADVATVKATFPAADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQPGLEEILVVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKIYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMQGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLDANIQFAQTVLKELAQEKGKAYLMPVRIKLEQY
LPALQDAVA
>A0A7S4C0C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chrysotila carterae|TrEMBL
MATETVTDCRKDLPEVTKGKINDMITEWTSKTSEPFISFEYFPPKTPEGVEKLHKTIEQM
AKQQPLFMDFTWGAGGATSELTLELSTECQKRHGVMVNMHLTCTNQEKEKCDAGLSGAKA
AGIRNIVALRGDPPKGQEKWEVTEGGFACALDLVKYTKANYGDFFSLQVSGYPEGHPDRI
NKASDLGRDMSATEKMRAVDVDGEIHVCSDDDFEKELAYLKEKCDAGGDVIITQLFYSME
VFEYFVSKCRAAGITQPILPGIMPLNAYGGFKRMTGFCKTHIPPAMAEKIETLKGDDQKQ
EFIDFGIEYVATLCEKLVSSKLVPGLHFYALNQSERTYQILRRLKYLKPE
>A0A2M7JZ15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG_4_8_14_3_um_filter_45_15|TrEMBL
MKTKSNLERVLESKNFAATGELGPPQSADPEVIRRKARILKDHVDAFNVTDGQTAVVRMS
SWAACLIGKEQGLEPIVQMTCRDRNRIALQMDVLGVAALGINNILCLTGDHQKFGNHPTA
KGVYDIDSIQFVKMVKDMRDEKKFQCGEEMPVEPRLFIGAAANPFADPFEFRVIRLAKKV
AAGADFIQTQIVYNVDKFAEWMKMVCDKGLHEKVKILAGVAPIKSVGAARYMKTKVPGMD
VPDSVIERLRGVTKEQVPKEGIKLCVDIINQVRQIEGVAGIHLMAIEWEEAVPEIMEAAG
LLPRP
>A0A0N0NFK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium OV320|TrEMBL
MTTLRDTLGRGTPSFSFEFFPPKTAQGERTLWEAIRRIEPLAPAFVSVTYGAGGSSRDRT
VEVTKRIAAQTTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPNAPWR
RHPDGFTHAHELVSLVKESGDFSVGVAAFPERHPRSPDWDSEIRHFVAKCRAGADYAITQ
MFFRVEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIARFAALSGAAFPEDLAHRLDAVR
DEPAEGHRIGVEHATAMAQRLLAEGAPGLHYITLNRSTATLEIHRNAANPRSARHVLAAQ
H
>A0A366IBE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalibaculum bacchi|TrEMBL
MRLTELFERGEFVVTAEVGPPKGINIDHLIDEVNTYLKDRVTAVNVTDNQSSVMRLGSLA
TCKAFKDEGIPPIFQVTCRDRNRIALQSDILSAAMLGIDNLLLLTGDHTTLGDHPQSKPV
FDLDSVSLIHAVKQLESGVDLAGNELVGEPPKFAKGAVVSPCSDSVDVQLAKMEAKVKAG
ADYFQTQAVYEPEKFIEFMEKAKQFGVPVMLGVVIPKSVGMVKFMNANVAGIHVPDHLIE
ELKKDKEKTKAGITGVEITARIIKECKDYCDGLHIMALGWESKVPDILTLAGL
>A0A645DIE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPEFCSVTYGAGGSTQAGTFTMVRDIQNE
GVGAASHFSCIGATHEKVRAELNELKAMGVKRIVALRGDLPSGYGLGGEFQYASDLVAFV
RQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VRALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A0A1ZJG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus str. GP2|TrEMBL
MKSKLQQTLEKKSKVITAELMPPRGGDPIRSLKIAQLLKDKVHAVNITDGSRAVMRMCSL
AMSKLLLENGIEPIMQISCRDRNKIALQSDILGANALGIKNILCITGDPVKAGDQQDAKA
VHQFESVKLLKQIQDFNKGIDPTFEELPDKKTFIYAGAAADPSCRNQKSLENRIRKKKEA
GAQFIQTQMVMKKEDLIEFCEKIAKPLDIPVIAGVFLLKSYKNALFINKYVPGANIPENI
LNRLKEAKNPLEEGILIAAEQAQDFFCIASGIHLMAVKSEHLIPEILKKADLSLEY
>A0A1R1Z2V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Sph1(2015)|TrEMBL
MTNTILTRAEAALAHEEPLFADVGGDIAVSFEFFPPKTEKMDTQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTMDAAAHLTCVEATREEIDQVAHEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPDSTDQASDIDNLK
RKIDAGANRAITQFFFSPEAYFRFRDAAAAAGITAEIVPGILPVSNVAQTRKFAAMCGAR
IPDWMDRLFEGLDDHPGARQLVAATIAAEMCRRLYAGGVKGFHFYTLNRAELAYAISHLL
GVRGKKAEAVVAA
>A0A2U8G4E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium fredii CCBAU 45436|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMEIQLFQTVADLSSFAPAFQTVTYGAGGSTKAR
SLTTVKRMIGEMGLRNTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGSA
YQPFPGGYESSAALVNALRARGDFEISVSAYPEKHPESSDVAADIDMLKRKVDSGATRAI
TQFFFDNDDFERYLERVRRAGVQIPVVPGILPINNLTQVIRFAGLCGSKVPEAIVSRLGH
LDDQPEERFKEASHIAAEQIVDLARRGVRDFHLYTMNRSPLIAAVCDLVGYGRRPANHTA
APSYRAVATA
>A0A371Y2A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. AcE210|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTFSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPMADWVAHPEGLTYAAELVRLIKESGDFCVGVAAFPAMHPRSEDWDSDVRHFVD
KCRAGADYAITQMFFYPEEYLRLRDRVAAAGCDTPVIPEIMPVTSVRMLERLPQLSNATF
PPALKERILTAKDDPAAVRSIGIEFATEFCAKLLDEGVPGLHFITLNNSTATLEIYENLG
LHDQRA
>A0A2E3QZQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermaceae bacterium|TrEMBL
MRVTDHYAAADEPLFSYEIIPPKRGSSVADVLGVVEALAPYDPPFIDVTSHSAEAIYDEQ
PDGTLRKRVKRKRPGTLGLCAAIQYRFGIDAVPHILCRGFTQEETEDALIELNYLGIHNL
LAVRGDDTGVAKLERPDRTRNEYACDLVGQIQAMNDGRYLADLLDAAPTDFCVGVGGYPE
KHVDAPNLTWDVLNLKRKVDAGADYVVSQMFFDNRHYLDWAARCREVGIDVPIVPGLKIL
TSKRQLQSLPRAFYTEIPEALAAEVEEAKDEHVPEIGIEWTRKQAEGLLEAGVPGIHFYI
MSTAKHVVRVAEPLRKLVG
>A0A2W6GPZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSAPTSLRAQAFLDAFSLEVSAKAMPALGAEAARIPRGTTISIPWLASEDDDARLAAARR
VRELGFEPMPHLSARRIGSRAVLERFLQRAANEAGVAQCLLIGGDLATPAGPFADSASII
ETGLLERAGIKAVAIGGHPEGHPVMGSVGCWQVLEHKCQAIEARGMAPMIITQFAFDADI
VLAWLDALRARGIDVPVLVGVPGPASIARLARYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDHLVSSLTDAHGLVSPHFFPFGGIAQSLDWIKRHRPQASAVGG
>A0A3E2D084|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium NR015|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VSYIRSKRPDLPILGACYPEKHPEAESLQADIENLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNADCLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A0R3GZK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides sp. H054|TrEMBL
MTTNPLDHDASVAELQDPGSIADRLAGVQPGDVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDLE
RDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEEQLLRAAGDGPEEDRDEVRKVGVEVATSMAARLVAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A3N1R415|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MKRYTDDEPAAAIAMTSLSFEFYPPKTDEQRSQLDRTAAKLRGFGPEYVSCTFGAGGSTL
SYTSETVRHLKQHHRFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGH
PGDLRYAAELIDFIRAEHGNAFRIEVGAYPETHPQASDALADLKHFKAKVDAGADAAITQ
YFYNADAYFHFVDAVRALGVSVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGRKMQAYG
DDSDSIRAFGAEVVAQLCQRLVEGGAPGLHFYTLNLAKPTTSVLKLLRS
>A0A2U4HD57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAGTSSQADAFINAFSLEVSAKAMPALRAEAARIRRGTVISIPWLASEDDDARLAAART
VRELGFAPMPHLSARRIGSHAALERFLERATSEAGITRCLLVAGDLATPAGPFADSASII
QTGLLEHSGIKVVGIGGHPEGHPVMSADDRWEVLGRKCQAIEARGMAPLVVTQFAFDADI
VLAWLDALRARGITVPVLVGVPGPASIARLARYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFMDRLLSGLTDAHGPVSPHFFPFGGIAPSLGWIERYRRRTSAASV
>J8FBN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus MC67|TrEMBL
MKLLDLLSKGVVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPNFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRVHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLTAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A540KE40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malus baccata|TrEMBL
MPINNYKGFIRMTGFCKTKIPAEVTAALESIKDNEEAVRLYGIHLGTEMCKKILASGIRT
LHLYTLNMEKSALAILQNLGLIEESKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYIS
RTIGWELYPHGRWGDSGNPSYGALTDYQFMRPRARDKKLVEEWVVPLKSVEDICEKFKKF
CLGKLKSSPWSELDGLQPETGIINESLGKINTKGFLTINSQPAVNGERSDSPSVGWGGPG
GYVYQKAYLEFFCSKEKLDALVEKCKALPSLTYMAVNKDGSWVSNTGQTAVNAVTWGVFR
AREIIQPTVVDPASFIVWKDEAFEIWSRGWARLYPEGDSSRKLLEETWNKPVPGGRWDAK
TPKICPVEQLVPPIFGAPNAGRNASSRSVPSCPTYQTHP
>A0A3G8R775|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. M-152|TrEMBL
MKPDLRTVLNGEIIVGDGAMGTFLSQLGFPVNTSYEELNITSPGVISDVHGQYLNAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLSISK
LELSRNYEQQIDALLSEGVDGILCETFYSLDEMRIALHSVRKYSDIPVICQFAVDQVGRT
QDGFLMAQAFSTLRSEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECATSFVDLGTRLIGGCCGTTPDHIAAISKALNNLKPPPLAPKETFS
TEVIHVVEQTADEGGRGNGRHTSEPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHALK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYIMTQPVYDPELITAIAEQTRHLEIPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGPEGRAMGVSIAKELLDTAMEHFNGIYFMTP
FMFYEMTAELTSYVWQKSGRVQAPLFRL
>A0A2G5X2N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. P16b|TrEMBL
MSLLEKLQTNVLTADGAMGTILYSYGIDYCYEELNIEKPEIIEQIHQDYISAGADIIQTN
TYSANAIKLARYGLESHVTDFNKAAIQIAKRAAAPGGQFVLGTIGGLRGIRKSDATLDEI
EKVVLEQANALLTGDPDGLLLETYYDFEELSSVVTTLKKITDVPLIAQVSMHDPGVLQNG
LSLNDALHQLESLGADIVGVNCRLGPYHTIQAFDNVTLPEKAFLSAYPNASLLDVEDGRI
VYESEAEYFGRAAVLLRDQGARLIGGCCGTTPKHIKAAKTQLARLTPITEKVVQPAKPIV
IHEADPAKHQPLHEKAKTERTVIVELDTPRHLETEDYIKGANLLYDAGVDAITMADNSLA
SPRISNMAMGSIIKMQHNIRPLVHLTCRDHNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELLQLIKKLNEGISFSGKPLRKKASFSISAAFNPNVRVIDRAVQR
LEKKIEAGADYFITQPVYTKEKIIDVYEATKHLDTPIFIGIMPLTNIRNAEFLHHEVPGI
KLSEDVLERMRECGEDREKSTETGLEIAKELIDTAAQYFNGLYLITPFLRYDMTLELYEY
IKKIDQQKERELTHAETSY
>A0A847QLI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MKKDFREKLLAKEKFIVTWELIPGRGAWESSQEKVLEQAEKAAKGNIVDAISLTDNPGGS
VAIRPDIIGQEIAKFGIETIIHLTCKDKNRNQLESTLYALERAKLNNVLVLTGDYDLETK
SGLPKPVFDLDSTQLLQMIQELNQGIVVKKAKGESRFKPCNFCAGAAVSPFKATEAELIM
QYSKLKKKIENGAAFIITQVGYDIRKFHELFLYTRQMGWDIPLIGNLYAVNFPTGRVMNN
NRVPGCVVTDKLLAELEQERQNPDKGKQAMLDRTAKLYALLKGIGYRGVHLGGYNIEYEQ
IEYIVGKGEELSA
>A0A7K7WKZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothocercus julius|TrEMBL
MVNENQHTCSASSSSKSDGGSSSGSEGSKDSSRCSTPVLDAERHERLREKMRRRQDSGDK
WFSLEFFPPRTASGAVNLTSRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPAGEEWQEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAENYEADLRHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWTEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGELNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYETRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A241UV64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4204|TrEMBL
MSLLAQYFAQQQFCVLVEYLSVQQAQSPVKTQFAGFPAAMTLADRVHADDDEAPLMVAKQ
YPQAIEKVIHFSGKARDIRDFEQFLQDAKIQGQKNLLLLTGDKLKQHHYSHDLEPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMAAL
QDAHAFLAQHQYAQKILACVMPLTLARAKFMLKHKVAGIVITPHILKVLQQEKEQGLSDR
VYVRCALQILMCRHLGFAGVHLSACHQPEEQMLLERYIEEYRHLSFAECERLWNTLWQVQ
TGTEFHPKLTYYSRPATSSQIIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDRTKANN
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTAILKEKLIPTVSIAVRGTSSWKNWYVESAD
>A0A241V0C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4204|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYASDLVR
FIREHSADHFKIEVAAYPEMHPQADSFDQDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPIINASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A0T6YQP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. Sb3|TrEMBL
MTAQTLYPAERGNLRLSFEYFPPKTDEMEVQLFQTAGDLSIFGPAFVTVTYGAGGSTKAR
SLTTVRRMVGEKGFANTAAHLTCVGAPKAEVDAVIDEYIDYGVRHFVALRGDPQGGIGSA
YQPHPDGYASSTDLVRAIRTRGDDIEISVSSYPEKHPESPDVAADIDMLKRKVDAGANRA
LTQFFFDNNDFERYLERVRRAGINIPIVPGILPINNLAQVQKFAGLCGASVPEAIVTRLV
HLEDQPVERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLVTAVLDLVGFEQVALEAN
NALDEAPRTRAAGAAA
>A0A7X1NPJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter bussei|TrEMBL
MTVLPLRVEVIPGENLVEKLRAYLPAPATVTVTCLPQHGPRAAVDLAVGLAAAGYTAVPH
LAARSVADRTELGDHVDRCLDAGITDVFVIGGDAPVAAGPYAWSGALMEEVAELSGGALR
MGIAVYPEGHPATAKDDLLATLRSKQDLASWCVTQLCFAPDTIRTFPARLRAEGITLPVW
AGIPGPVRISRLLRLAGSIGVGQSLGFLKRSAGGSNSGSVVRQLVTSASYDPAPLVEALD
GAGYAGLHLYSFNDLAELADSGLVEPVAPGA
>A0A7W7A7V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium taihuense|TrEMBL
MATPLIHPNWDKAPDGITDGFSLEMTAKDEASLREAAPLIPADTPVAVTFLPGEDVSARV
AATVAVRQLGFEPMPHFSARRITSEDDFEGYLKAVVEQAGVERCFIVAGDPPEPVGPYFD
TSALIATGAFERSGIKAIGIGGHPEGHPNMTEAECWAVLEKKVAEITARGMAPLIVTQFG
FDPDAFLAWLLELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVTN
LLGTAGPDKLVDAFAKGLGPQHGKVRLHFYPFGGLTKTLEWIHGYNKKHGIGQGA
>A0A6N9YGF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytoactinopolyspora alkaliphila|TrEMBL
MPTPDALDRVAELPAGSTVTVTASPRRGSEATVELVEQLAARGFAAVPHLAARRISDESE
LNAILARLHAAGVRDLFVVGGDSPAPSGDFADGAALLKAIDAAGFGFERIGVPSYPEGHP
HVDDDALWDALLVKQGYATYTVTQMCLDATVVGQFISAARRRGVTLPVIAGVPGPVPPAT
LLRMGLRIGVGDSLKFARGHRKLARAFLRPSGYRPDALPLALAAIPSPGPIAPGPAGLHI
YTFNETAAAAQWVDHLRRTVVQSAPQSAPHRREGRT
>A0A345UGS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Cyclonatronum proteinivorum|TrEMBL
MKVTDFYAQSSEPLISFEIIPPKRGKSINSIFEALDQVMPYRPPFIDVTAHAAEAYYEEL
DNGNIRRHIRRKRPGTIGLCAAIKHRYNVEPVPHILCKGFTREETEDALIELNFLGIQNV
LAIRGDDHGAPKPYNADRTINEYAVDLVRQVKRMNRGLYLEQLMEADKTNFCVGVGGYPE
KHFEAPNLNWDILRLKEKVEAGADYIVTQMFFDNQKFFDFEAKCREAGITVPIIPGLKLI
TSYRQLTTLPRSFHLNIPEPLSHEISLKPDRARDIGIEWGVQQCQELLNHGVQGLHFYVM
ANPSAVIDVLDHLKTGLKSRAV
>F7XMS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosalsum zhilinae (strain DSM 4017 / NBRC 107636 / OCM 62 / WeN5)|TrEMBL
MHSLFQDKIRSGSFVITAEITPPKGTDTTKAIENADMLRGCVDALNITDNNRAVMRMSPV
ALGAILQERGHEVIVQMTCRDRNRLALQSELLGACALGIGNICVMTGDHVKSGDHQGAKS
VYDLDSVQLLSMIRKMMNGSDLYGNPLESAPEFMVGAVSNIDPGQAMQMLKFKKKIIEGA
DFIQTQAVYDSDLFEGFMEYAREFKVPVIAGIIPLKSAKMARFMNENVPGIQIGEDLIER
MEQARDPVNEGLEISCEIISRIRPICQGIHLMPIGQHLNTQRLLEMAGFSKQ
>A0A7C1MX25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobi bacterium|TrEMBL
MRILLPNDRGTSLHVLMAIPTFRARLEDARPIVAVGSVEHALSNRTHDRIELVVLQAPQV
LEETMHAFVEAGAELLFTPTERASRLWLAQLDRADRVYELNRKAVWIARKAAAHRAFVAG
TIGPPPTMLHPIGPLSTESLRRAIAEQAIALLDGGCDVLVLKSFIELDELLLAIETVLPL
ANGTPVIALKAFPEDGAVLATSFPADVARLLSQYSLAAIGASGTVGPQRMRGVISAMRSR
SSLPLVALPDTGIPTMVGCRAHYSADPDYIARTLRELAESGARICGTDRGTTIAHTSATS
QSLAGITQAAPPPAPIQREAHLSARPTVPPPSRFAQKLRERFVITVELDIPRGLDMASVL
DGARYLGMHGVDAVNISDGARARLRVNSLMLSAYVQQETGIECIAHLACRDRNMVALQSD
LLGAALLGVQNILAVSGDPTHIGDYPRATTVGDLDSIGLIRALRMMNSGRDLAGNPLSGT
TNFCIAGACNPCAEDIERELDRLAQKVAEGAEAIFTQPMFDLEQWLQFLSRAGSLPVRFI
VGILPLRSVRHAEFLHYEVPGMTIPAWVRKRIAESPNPAEEGITIAAEFLAAVKEHCHGV
YLMPPFKKYDVALSVLERAGVALASRPDH
>A0A7X1M729|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ochrobactrum sp. CM-21-5|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLKPEFVSVTYGAGGSTR
ERTVRTVARILKETDVKPAAHLTCVDATREDVDHVAREFAALGVSRFVALRGDPANGIGE
QYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHSFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKAEAVL
ELA
>A0A849K7R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Isoptericola sediminis|TrEMBL
MVAEASPHLPAPPRPEPSRPTVSFELMPPRRPDAAPRFWETARRLVAARPDFVSVTYGAG
GGDRDTARDVVSRLLAGTPVLPIAHLTCVGASRENVSEVVDEFLEAGVRSFLALRGDPPR
DQPDWRPPAGGVHSAVELVHLLREVEARRCATDPAAAVRGAARPLTIAVAAFPDGNVQAG
TTRAQEVRRLLEKQQAGASFAVTQFFYQADSYTDFVAEARAAGVTIPILAGLLPTTEPRR
LRRVEDLTGVRAPRHLLDALDARPDPEAQYAYGTAYGTELAQRVLDAGAPGLHVYTFNKH
RPALDLLEGVHLGGPASVPVDDADLAGRPWVPSIPTPAPAAL
>A0A1E8BHK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPNFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKKTIVRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLTAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>K2FLM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAADLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVEKVQAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNSSNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A3B8QGE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
MKVVDHIQAAKGKTLFSFEILPPLKGTRIDELFGTIERLMAFGPKFVDVTSHREEFIYKK
RENGLLEKVHTRKRPGTVGICAAIQNQFKVDTVPHVICGGFSREETEYALIDLHYLGIDN
VLVLRGDALKAEGAFKPEPHGHTYALDLLKQVDDLNHGRYLHDEVENSNPSNFCIGVAGY
PEKHFEAPSLKTDIKHLKAKVDAGAEYVVTQMFFDNQHYFDFVDKCRAAGINVPIIPGLK
PIATASQLATIPRNFHLNLPDDLVDAVEAAKTPSAVKEVGIEWCIAQSKELMEKGAPVLH
YYTMGKADATEKIASALF
>A0A2H5YUJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR26|TrEMBL
MSDRRESSQFGDGAEVEWVCRLLDNARLEILPTAKADEIVKGVPERYKLTVTSSPKHGVA
RTMELAIDLHRRGFTVVPHLAARAVQDRQELARIIDALVDAGIDEVFVIGGDQEQPVGAF
TSALELLDALSTLERRPRTIGIAAYPEGHPKIPSDVLLDTLLRKQQHAAYAILQMSFDAG
AIMSWLRSAKRQGFGLPVYLCLPGTLRIDRLLRIAVRLGIGQSLRYLEKQQGLLPQLLTG
GYRYDPWSLIQALLAQFTPDHEQIVGIHWSTFNELARTIEWIEGKQRELRVTAR
>K1ZJ22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MPKFEKWMEGVREKGLHKKCYILAGVTPCKSLGAAKYMANRVPGMDVPKEIVDRMASVPK
EKQAEEGVTICVETIEKLKKIEGVSGIHIMAIEWEEKVQEICERAGLLPRPQV
>A0A4R5U1E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas aestuarii|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKTHGPEYVSCTFGAGGSTLSYTADTVRRLKDAH
GLDAAPHLSCVGGTRDEIGQLLREYRDMGCRRIVALRGDLPSGMGHPGDLRYASDLIAYI
RREHGDHFHIEVGCYPETHPQAGDALSDLRHFKAKVDAGANAAITQYFYNADAYFHFVDA
VRALGVEVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDADSVRAFGADVV
ASLCQRLLEGGAPALHFYTLNLARPTQAVLSRLG
>A0A4V3MKF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M3A.F.Ca.ET.201.01.1.1|TrEMBL
MNQFRFSRRPDIGHKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVRRILTESTLTPAAHMTCVDADRDQVDTVIQEFAEMGVTRFVALRGDPAAGVGT
AYRPHRDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFSQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A1I6KBU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces sp. CF514|TrEMBL
MAPTEPDTAVAATRRTPLSFELYPPRTDAAAIALGRTIDRLADVDPAFISVTFGAGGSSR
DRSLTVLRYILENTTVEPMAHLTCVGSSHAEANELVRKFQDAGIRSFLALRGDPPAGSDP
DAPLGDLASAAELVQLIHRVQQEREPFDQVAVEGNPGASRIRERTRKTEVAVAAFPTGHP
QSRDLSRDVDILLAKQVAGANLAITQLFWEASDYLGFVERARAAGVTIPILPGIMPTTTS
KRLARLTELTGVQPPASFAIALEVEPDPAAQTELGIAFAARLAAEVIAGGAPGLHLYTYN
RHEAVLDVVERLGLGAPHQLANERNTAR
>S9QH44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoreibacter arenae DSM 19593|TrEMBL
MALLNFKRTAPAQDVTVNPQVETFLKDYSIEVMPRTAEKVEDFRELLPEGTRVYIAHIEG
TPIDEMVATAGRLHRDGYKVMPHFPARIIKDRATLADWIARYQGEADVKQALLLAGGVAT
PHGEFDSSMQLLESGLFGDFDRLHVAGHPEGNRDIDTDGSMKNVSDALAWKQKFSETTDA
KMALATQFAFEAGPIIEWANSIKAAGIDLPVHIGIAGPAKLQTLIKFAIACGVGPSLKVL
QKRAMDVTKLLLPYEPNDVIAALAAHKAANPDFNIEAVHFFPLGGIKTNSNWAIANGGAS
AVPANHA
>A0A3B8QQB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
FIDVTSHREEFVYKKRENGLLEKVHTRKRPGTVGICAAIQNQFKVDTVPHVICGGFSREE
TEYALIDLHFLGIDNVMVLRGDALRADGAFKPEPNGHAFAIDLLKQVVDLNHGRYLHDEV
ENNNPSNFCVGVAGYPEKHFEAPSLRTDIKYLKAKVEAGAEYIVTQMFFDNAYYFAFVDK
CRAAGIEVPIIPGLKPIATGGQLATIPRNFHLNLPDDLVDAVEAAKTPAEVKQVGIEWCI
EQSKELMQKGVPVLHYYTMGKADATEQIASVL
>A0A4R6U8M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureibacillus halotolerans|TrEMBL
MTLRTKLENDFVIMDGAMGTYLYDTYQVQSCFEEVNLTQPTIITEVHKSYVDAGADLIKT
NTYAANAIKLAKHQLADKVIDINAKAVELAKAATEGTDAYVAGTIGGIRGVTRTETTLEE
IEASFREQLQVFLDNGVDAILLETYYDEEELHTVLKIAREATDVPIIAQLALQEAGRTQN
GTPLTAAFLTLESLGADIVGINCRLGPYHTIEALRYVPLMEDAYISAAPNAGLPDVQDGR
LFFKAHADYFGECARSLRDQGARVIGGCCGTTPAHIAAMAAAVRPLTPLTEKQVPLAPHD
VIEVVSQPLGIEPLHVQMKTRTSVIVELDPPKHLVVEDYFKGAALLQEAGVDAITIADNS
LASPRVCNTAIATILKTKYNINPLVHLSCRDRNLIGLQSHLMGLHTAGIHEILAVTGDPT
KIGDFPGASSVYDLQSFELIKLMKQFNNGYSHSGKPLKEKTQFSIAGAFNPNVKYLDKAV
KRLEKKVANGADYFISQPVYSEEQLIDVAEAIKTLDAPLYIGIMPLTGHRNAEFLHHEVP
GIKLTDSTRAIMAATKDDPAAARREGIAMAKQLIDVALDYFPGIYVITPFLKYEWSIELV
HYIHEQTQKKQQPVTPFLQ
>A0A484B8P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila navojoa|TrEMBL
MSRSRTAALLPQLLRKVTPLTVQNRVYRLNKRNQLTERTERVSTEQLNMHTLEANATRNF
AGNASQVPIEPCFRYTPEQVACAGEQPYVSDVVLSKEERREFFYGIEITAQNNGKLTCVD
FNSFLPILPSFISIVWLPHYWNVSPLERVETLQMIRNLEPYIPAMPHFSVYKQTEERINE
FFSLNFKNLLAVRGDMRDDNQFYLFGHQLVEHARRVRKEYISIAVPGYPEGNKKLDLDQD
IAFLKNKVDKGADFVITQMCYSAELIIKYVKAARDVGIVTPIMVGVVVPESLKAYRIMEK
ITKITLPEKKLAELEKVQKDDAKVREFFVQLALCTILQVLDAKLDVYGIQFYTMNRFGAV
HDVLRELRKLGILKKTPPDACEDA
>A0A3P7KCX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strongylus vulgaris|TrEMBL
CRCFGRSALEVFNPRFAGYPLGHPEAPSYKADLLYLKSKVDAGAQFIVTQLFFEAEVFEQ
FVRDCREIGITVPIIPGIMPIMGYDSIRRIAKLSQLTIPEKILLDLEPIKHDDDAVMKYG
TVKAIEMCRRILSSGSAPSIHLYTMNREGACR
>A0A553KT35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus sp. LEMMJ03|TrEMBL
MDLTTKKDLREYLQDHLLVGDGAMATQLYRSGVPVGVSFEELCLTNPRLVHDVHKAYYEA
GARLLETNTFGANRDALARYGLEHKVTRINRVAVTIAREAAQDDAFVVGSIGSILAGRVR
KKVLDEYRDQFEEQAIALLHAGVDGLILETFLDLEELLLAIDVIRPLTGLPLICQLATLD
VGRTRDGYTLTEAFSHLQKAGADIIGLNCRLGPAEILRSFESARVPDGALLSAFPNAGRL
GLSDGEYAYKSSPEYFAESALRLREQGVRLLGGCCGTTPDHVRAMAEALKGLAPQARVNP
PDELTERPSVSSFSVRDRQKPSIVERVKTGTTIIVEFDPPKDLDTEGFLTGCCELHKAGA
DAITLADNSLANVRMSNMALGAIMKSQYGIDPLVHIACRDRNLIGQQSHLMGLHALGIDQ
VLVVTGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGISFSGRPLKQKAQFIVGAAFNP
NVRHIEAAIKRLEKKVEAGADFIMTQPVYDAESIRLVHEATKHIGIPVFIGIMPLTSSRN
AEFLHNEVPGIKLSDEARERMRRVQGEAARQEGLKMAKELLDVAITYFNGIYLITPFNYY
AMSVELIQYVRQQSHLLKAAAKA
>A0A833FKK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella seminalis|TrEMBL
MVTSLREKHQAGQFTITVELDPPKSASVNKTFKEAAQLLDKVDAINIADCPMAKLRMSPI
ALAHLIKFRAQIDTIFHLTCRDRNILGLQAELLGAAALGVNNILTLTGDEPSRGDHPDAK
PVFEVDSIGLLKIANTLNNGFDLAGNPLDESTNFYIGTTGNPGADDLDAEKAKIIRKIEA
GANFIQTQPIYDLEKAKRFVDMVEPLGLPVMLGLIPLKSFKMATYLHTKVPGISLTDDIL
NRMEKGGKEAGLEIALETLLAIKQIAHGVHIMPLNDIQTVLYLIDHIS
>A0A2T6KHY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenisporosarcina sp. OV554|TrEMBL
MSFLGKLKNQILIGDGAMGTLLYSYGTDCCFEELNLSHPEQIQNIHKAYIGAGADVIQTN
TYAANYIKLQRYGLEDSVKEINSAAVHNAKIAARNEAYVFGTIGGNRGVKPNSISLEDLK
RSFREQLYCLLLEGVDGILLETFYDLQELEAVLPIARKETNLPIIAQLALQEPGILQDQT
PVNEAFLQLESLGADVIGLNCRLGPHHTLLSLEQIEIPAHSYLSAYPNASLPAYTDGKFH
YEGDAEYFRKSALAFRNEGVGLLGGCCGTTPDHIRAFASELKNVVPITQKVVKIKPAKRV
VEAISIKREFPPLEKIVKEKPSIIVELDPPRKLDTTKFFKGAKALKEVGIDAITLADNSL
ASVRISNESLGYLVKTQLAMRPLIHIACRDRNLIGLQSHLMGLHTLGMNDVLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTAFSIAAAFNPNVRYLDKAVQ
RLEKKVQLGADYFISQPVFSEEKLLEVYESTKHLNAPIYIGLMPLLSSKNAEFLHNEVPG
IKISKTIRDRMAKFNDNPVQAVQEGLEITKSLIDTALDLFNGIYLITPFLRYELTVELAL
YARQRASELQRNRIAVSTIHSFN
>A0A514WKN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. IC081|TrEMBL
MTSAQRPALAPALGCLPGDISVSFEFFPPKTEKMEEQLWDAITQLAPLAPSFVSVTYGAG
GSTRERTHATVARLAAETNLVPAAHLTCVGASKGEIDEIADQYWEAGVRHIVALRGDPPP
SQGGVFTPHPEGYASAADLVAGLKARHDFDISVAAYPEVHPEAASAQSDLDNLKRKIDAG
ANRAITQFFFSAEAYFRFLDKTQAAGITAPILPGIMPVTSFAAIRRMSGNTEIPVWLEAM
FEGLDERPGPRALVAAVAAADLCRNLYEGGVRDFHFYTLNRAEQAYAICQLLGLRPKLQE
LRESA
>A0A087BNS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium minimum|TrEMBL
MHAPGFSLEVFPPRRNGPVRTIYDTLDGLEGLSPDFISVTYGHGSQADRSATARIASTIA
HEYHIPVVAHLTSLYADEASVDETLTAFDEAGVNAILALRGDPVESHTPTGVFPHASDLA
AYIHRRRPDMTLVGACYPEGHADSPSLEEDVSNLAIKVSAGVSQLITQLFYDNEDFYRFM
DVCAAHGITVPICAGIMPIISEKSVRSMASRGGSHIPPKVEALLDRWGDAPDCLRSAGIV
YASEQIADLIANGVAGIHLYTMNRPSTTRRIWRNVSGLFASD
>A0A2N4Y4S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. TH135|TrEMBL
MAQIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKVF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMAKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDHVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGILKGRQPWKREHARADDIAAQRMREIGADPVQDQQEMAGRAA
HSQTH
>A0A545VBU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cordyceps javanica|TrEMBL
MPPRRPEASSAVVAIPLASTPPSAATNAPPNDNDDGNVSFVDDDLRPPSHQEPRSISSSR
YDAQPITAESEMEKITDKIAALPADGEYFSLEFFPPKTAMGFSNLRDRLQRMEQALRPLF
VNVTWGAGGSTADKSLELAELCQRELGMTTCLHLTCTNMSRKLIDKALDDAKALGIRNIL
ALRGDPPRKEEYRAANDDDDEESENEGQDFVWAVDLVKYIRKKHGDYFCLGVASYPEGHA
DESHPLGQSLQHDLPYLVEKVQAGADFIMTQLFFDIDAYEKFEATLRQHPSGAFKTIPIM
PGLMPIQSFAMIKRTAKLSHAAMPPAILERLTAVKGDDERVKAIGVDILSELVEQVRTVK
SKTPGPKGFHFYTLNLEKAVTFILERTNLIPDEPAAEEAVLVDGGPTSAPFLQVNGHAIP
APRSHSHSRSSRRHSSVGSDPHNRVIASEGGRRTNPEWEVMGAEAAMPAEQLNARANTLA
ISEGEGALGREATWDDFPNGRFGDSRSPAYGEIDGYGVSLHMSVTQAVKLWGHPTTKHDI
DDMFVRHVRGELDALPWSEEELLAESSTITPHLAALNAKGWWTVASQPAVNGIRSADATF
GWGPANGFVFQKAFLEFFISSADWTALQATLQRPGVREVVCFYASNARGDFLSSDNSGSA
AATTTSISTSSTNAVTWGVFPGKEIVTPTIIEEVSFRAWCEEAFGIWDEWSRVYGKGSPS
ATLLSGIRDDYWLVNIIHHDFVDQQALWDLLLA
>A0A1X0R452|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus microsporus var. microsporus|TrEMBL
MKVIDKIKKAEAENRSFWSFEYFPPKTPQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
ELTTEIVATAQSVYGLETMMHLTCTNMPIQQIDDALEAAKKCGCQNILALRGDPPKGQAN
WESCEDGFEHAIDLVRYIRKKYGDYFCIAVAGHPEGHIDNPDKEDDLLRLKEKVDAGADL
VVTQLFFDVDMFIEFYKKARAIGITVPILPGVFPIQNYSGLKRVIAFNDNFVPQKIWDDL
EPIKDDDTAVKEYGINLAVEFIKRFREVGINGFHLYTFNLERSSRLVLERLELVAPLESI
KPLPWSPSLNTKRAKENVRPIFWKNRTKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
INLRYPVEQCVNMWGTPKSVDDVALTFARYCKGEISGIPWSSQQLDPETDIIRQRLAAIN
LLGYFTINSQPAVNGVKSCHPIYGWGPKNGYVYQKAYLEFFVSPEKLNELIDKISQNPQV
TYYAVNKQGDLRTNTTSDEPNAVTWGVFPGKEIIQPTIVESVAFMAWKDEAFELWNRWAR
IYERDSESAKLILDITDSYYLINIVHNDFQDENGIWRLFDLEIDGEISRKLLQSSVAR
>A0A4R4LVN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. 7K534|TrEMBL
MRRLRPDRPPTVRELLASGGRSFSFEFFPPKTDKGALNLWRAVRELESLQPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVDHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMAEWVKHPDGVEYAADLVRMIRSYGDFCVGVAAFPYKHPRSPDIESDTRYFIEKCRA
GADYAITQMFFRAEDYFRLRDRVQAAGCDVPILPGIMPVTQMSTIERSEQLSGAPFPPEV
RARFEAVADDPEAVRRLGIEHAAELCRELLEQDAPGIHFITFNKSTATREVYGLLDAASY
GGRGSAPPMTA
>A0A5A7NRP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zafaria cholistanensis|TrEMBL
MERSKTAPSPQSRQVLAGLVRNIGYEVMPFKGTEEKVLKNVPASVPLTVTATGGKGIEVT
VDLATRLRARGYSVAPHLPARLFRDEAELSGVVDQLREADVRRVFIIAGDAPQPAGQFPD
ALSLLKSMDAMGHHFEEVGIGGYPEGHASFPAAAIEQALEDKAPLATRILTQICFDAKTT
TAWAAGIKQRGVDLPVFVGMPGPVSRQKLVRVSAGLGLGQSARFLQKQQNMLWRFFLPGG
YRPDRLIRGLAAAVPKADTNIRGFHIFTFNDLAETEAWRRRLVQSVAEQVQSVAEQEER
>A0A2U2ZMY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Act143|TrEMBL
MGAAGLGALLERVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLAARLAGH
GYRVVPHVPARLLRDDAHLKDVVDRLAGAGVDDVFVPAGDADPPVGGFDGALPVLRRLSE
LGSPFARVGVTGYPESHPLLDDDITIQAMWDKREHATYIVSNLCFDPRVLGEWLVRVRRR
DVTLPVHVGVAGPVQRAKLLAMATKIGVGESTRFLTKHASWFVRFATPGGYDPERLLSRA
EAALTAPSAGVAGLHLFTFNQIAETERWRRALLDRLGA
>A0A192CF04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O25b:H4|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7Z9MT02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIEHIDNAKDPLFSFEIIPPIRGKSAQEIIDIVKDLEPFNPPFIDVTSHPAEAYYEEN
TDGEVKRRVRKKRPGTISICGIIQNRFKIDTVAHLLCRGFTREETEDAIIELNYLGIHNI
LAVRGDETNYKKPVQAGRTVNVFASDLVKQLNDLRSGIYLDEIINADPVDLCIGVGGYPE
KHFEAPNLKKDIEYLKQKVDAGADYIVTQMFFNNADFFHFVDECRKAGITVPIIPGLKIL
NNPKQLTSIPKNFYVNIPTELSEAIEKNPKHTREIGVEWCLKQCEELLESGIMCIHYYIM
SGASAVTKVLKELNK
>A0A0H5C4R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyberlindnera jadinii (strain ATCC 18201 / CBS 1600 / BCRC 20928 / JCM 3617 / NBRC 0987 / NRRL Y-1542)|TrEMBL
MRISQKLLKAHEADEAHPHEDKPTFSFEFFVPKTSQGVQNLYDRMDRMYNLNPQFVDVTW
NAGGRLSNLTTDIVSTAQSVLGLETCMHLTCTNMPVELIDKALKDAYDSGCQNILALRGD
PPVEGGEWTAVEGGFHYARDLVEYIRKKYGDHFDIGVAGYPEGHPEESDSDKIVGYLKEK
IDAGADFIITQMFYDADKFIEWCAKVREVGITVPIIPGIMPISSYAAFKRRATWCEINVP
QHFEDKLISIKDDDQLVREAGTELVAEMCQKLLDSGYVNHLHFYTMNLEKSSIMILEKLQ
LISSKAADDLPWRKSLNPNRQNESVRPIFWKNRKYSYITRTQGWDEFPNGRWGDANSAAF
GDVELFTAGLLRQSPKRAIELWGEPQTLEDLSNLVIRYLNGQLNSLPWSDTPVTSEVGSI
RDELNKINKAGFFTVNSQPRVNGSSSDDPIFGWGPKNGFVYQKQYLEFLIQRKKLPKLIQ
KIDEINAPYNKNSSSKDNYNILTYFAIDYSDDLNSNTKDDSANAVTWGIFPGNEVHQPTI
VEKVSFLAWKDEVFRILHEWSGIFESGSKAKDLIQSIVDDYALVNIVDNDFVGQDKIFGL
FQDL
>A0A2N3R4C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum subsp. globosum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLTEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAF
IRERRPDMKIYGACYPEKHPQADTLDHDIDNLKRKVDAGVTHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDRWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWANVQDLFA
>A0A5J0CCN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Telelkebir|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4Z0FJN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium columnare|TrEMBL
MKVTEHIEKASGKTQFSFEILPPLKGQNIQCIFDGIDPLMEFNPPFIDVTYHREEYEYKE
LGNGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGNEYASELVKQISDLNNGKYLDADLQNTNATDFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIANGADYIITQMFFDNKKFFDFVSKCRKAGINVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMAVVKAKDNEAVKQIGIEWCIQQSKELVKAGIPVLH
YYSMGKAENIKAIAKEVF
>U9SW98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus irregularis (strain DAOM 181602 / DAOM 197198 / MUCL 43194)|TrEMBL
MKVINKILKAHEEGRPSWSFEYFPPKTQQGVQNLYDRMERMYRLGPEFIDVTWNAGGTTS
QLTSEIVATAQSVYGLETIMHLTCTNMPKEKVDKALKDAKECGCQNILALRGDPPRGQEH
WEACENGFSHAIDLVRYIRQQYGDYFGIAVAGYCEGHVDNPDKDDDLYRLKEKVDAGADF
IITQVFYDVDIFLNWVKKCRAIGISCPIIPGILPIQNYSGFNRIITLSKTIVPQFVLEEL
EPIKDDDAAVKEYGIRLAVDMIRKMFADGIKCYHFYTMNLERSTRLILEALEFVPPIENV
KPLPWCPSLSAKRKKENVRPIFWRNRTKSYIARTEAWDEFPNGRWGDSRSPAFGELDGYG
VSLKHSKKGALELWGYPQKHSDIFDVFVQYCRGEVNSLPWSDQPLAEESNIIREQLAHIN
SLGYLTINSQPAVNGVRSDHKIFGWGPKNGYVYQKAYLEVFISPTQLDALIARIERDTNI
TYYAVNKQGDLKTNTQSDGPNAVTWGVFPGKEIIQPTIVEAVSFTAWKDEAFELWNEWTK
IYDTDSISAKLITDIADNWYLINIVHNDFHDSDGIFKIFEQISVTDYEADR
>A0A161TJ77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei|TrEMBL
MSTTLTHADPTLDSTFRDVAQRPPIGPSLTGRPRLRTSASAPENALETDLDAERPRRLAL
SFEVIPPRSQAQAATLPALLAELDTLAPDYLAVTSSAKSGWLHGTADFIRLVTATTHLRP
LAHLACTAGTRAELTTWIHHLLGVGVRGFLAIRGDFPDGATAVPDGHLPHADALVHLLRE
IESANTARLAAGRLGIGVAAYPSGHPESSGSDEDLDVLAAKQRLGADFAITQLFFDPRAY
ADLRRRAELAGITIPLIPGVLPVTDPRRLHTMSRLSGLAVPDDLLRRFDGAADPATARRI
GLEMTAEHIAAILAGGADGLHIYTFNDQATTLDLLEMLDRLGIRLDSAPAPVPASAPQPS
>A0A816DBC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria magnacalcarata|TrEMBL
MEFTLGDNETVPGDCKMHAHETHLESIHNLNRLKRIESEGANIAGKICSLQSAKYVSLTE
KISKRIADNDRWFSLEFFPPRTPSGAANLIGCFDRMAAGRPLFCDITWHPAGDPAGNKET
SSMMIANTMLNYCGIDTMLHITCYGAKKTAMLEYLYKAKDCGIRSLLALRGDPHVGEEWN
PAKSDFRYALDLVKFIRKHFGDYFVICVAGYPQGHPDSTSYEDDLGYLKEKIDCGADFII
TQLFFQAETFIKFESDCRSIGIKCPIIPGILPIQGYASLRNIVRLAKLDVPKEILACIEP
IKDNDEAIRNFGVQACLDLCRTLLDSGKVNGLHFYTLNREFATIEILKKLGLWLDEQSLR
ALPWKKTSFSHARSQENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGISSAPSFGVLTDYH
LFYMKIDATRDELLDEWGRELTCEQDVWKMFACYIGGEKNSIDKVVRRFPWTDEELSAET
TLIQKSLVEFNKRGILTINSQPAVNGKSSSDPVVGWGTPNGYVYQKAYLEFFTSAENIPA
LRSVLKTFPGVNYHFVNKSGEVNETNTDDEQPIAVTWGVFAGKEIVQPTVVDPVSFMIWK
DEAFSLWTERWGKLYEPESRSHAIIEEIANTYFLVNLVDNDYPQDSCLWAILDSMFEYQK
LPKKNIES
>A0A2M9Y6J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira brenneri|TrEMBL
MHISQILGKKQTTISFEFFPPKNQEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEKTGLTIISHLTCVGSTKDEIKEILKRYQKSGIHNIMALRGDPPKGQTEFQQT
ENGFAFAGELVGFIKKEFPEMGIGVAGFPEGHPSTPNRLKEIDHLKWKIDQGADYICTQM
FFNNHYFYDFVERCEIAGIKVPIIAGIMPVTSRKGMARMAELSLGTSFPAKLLKSLSRAE
DDTYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRKIYESLGVRNFDSIG
>A0A173XV29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia obeum|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A0K3CLL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosporidium toruloides|TrEMBL
MTTTPELRSSHPSTKVVDRIAQLDPSKPFYTFEIFPPKTDAGLVNLLDRIDRMSALNPAW
MHVTWGAGGSTQERSLQLAGESQSMGLETCLHLTCTNLEEGVLDRTLERAKELGVVNLLA
LRGDPPRGEEYWTASSDKFQHATDLIKYIRKEYGDDFCIGVAGYPEGHADSADKLADVEY
LFEKQQAGADFVVTQLFYDVGVFMEWYRACRKRGITIPIIPGIMPIQNYLSFRRMTNLCG
THIPPQILDDLQRIQHDDAAVKEYGVQLAVKMMRELFENDIRGFHLCTLNLEKSVTRVLE
LLQWVEPGSTKISARLRKGLSPNGAPLPKVINSLRPAPSTGANVAGPDIARKDSPASWDE
FPNGRFGDARSPAYGEMDGYGVSLKLPPGEAMRQWGQPTALSDVSRVFSSYLRGSLPSNP
WSEEPLRAETEMISSHLIEMNDKRHWWTVGSQPAVDGAPSADSVHGFGPKGGYVYQKAFV
EFFLTKEELDELERKSDEDERRRRESGEGDDGLIKWFAGNAKGDFRCNMGKGDVNAVTWG
VFGAKEIVTTTLIEEMSFRAWCEEAFALWNEWSLLYPANSPSRTFIRSLADSRWLVSVVH
HDYKEKDALWKWLLALKRPEEAQGAANGEAEGR
>A0A1R2CNI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stentor coeruleus|TrEMBL
MKIIEAIEKCKDDGTFPFFSIEFFPPKTEEALFNLQQRIERMSQNLGPLFIDLTWGAGGS
TFKESLELSSWIEQYSGCEVMMHLTLTNISLDVIDQALNKAKEAGICNILALRGDPPRGQ
ERWTHSVENFQYARDLVRYIREKHGNYFGICVAGYPEGHTECSDIDADISHLKSKVDAGA
DFVITQLFYDVDVFLKFVNKCRESGINCPILPGIMPIQSYQGFHRMVSMCKVSVPQYILD
KLEEIKSDDDQVKAFGVEVAVQMCKKLLANGIQGLHFYTLNLERSVTKIIQELKVVKLGR
EAPWLRPANRHQEWVRPINWSKRPKSYIERTTNWDDYPNGRWSDSRSPAYGFSFSGTNVN
YTNKQKEALRAIWGNPLTIKDISTVFLNFLNGQISRLPWFEEQGLQTETLMIKDFLINLN
QYGLFTINSQPKVNCASASDVKVGWGPRNGRKGGYVYQREYIEFFCPRDSLNVIKEILDN
YPTISYIAVNILGEEISNITEGDVIAMTWGIFPNREVLQPTILDPYIFKTWWKDEAFGVW
ANEWGEVYARDSESFALLQNIRNNYYLVNVLENDFVEGNLEKVFTEALGSLTKL
>A0A1C5XAA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MKTCELFKEKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLISFIKKHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A840ECL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinibacter ruber|TrEMBL
MKVTEHFDRESEPLISYEIIPPKRGGSADQILGVVEELMPYEPPFIDVTSHSAEVEYKQK
DDGTWTRCVKRKRPGTIGLCAAIEARFDIDTVPHILCKGFTREETEDALIELNYLGVENV
LAIRGDDNGYEKSISGNRSRNEYAVDLVRQIQDMNEGTYLEDLMDAEPTDFCVGVGGYPE
THFEAPNLAWDIMRLKEQVDAGADYIVTQMFFDNEYFFNFVDKCREVGIEVPIVPGLKIL
KRKRHLRLLPKYFHTEIPEELAAEVDAADPDDVERIGVNWAIRQARELMEAGVPGIHFYI
MSSADTVKKVVEPMHEEVA
>A0A1C3CDW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus polymyxa|TrEMBL
MKPDLRTVLNREIIVGDGAMGTFLYQLGFPVNTSFEELNITSPDVISDVHGQYLSAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
LELARNYEQQIDALLSEGVDGILCETFYSLDEIRIALHSVRKYSDIPVICQFAVDQVGRT
QDGFLVAEAFSVLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAKSFVDLGTRLLGGCCGTTPDHIAAISKALNRLQPPPLASKEALS
KESFQVAEQIADEGERGNGRHTSEPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHALK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYVMTQPVYDHELIAAIAEATRHLEVPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGPEGRAMGVSIAKELLDTAMEHFNGIYFMTP
FMFYEMTAELTSYVWQKSGRVQAPLFRL
>A0A3T3GAY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Braenderup|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7H4H5M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hominis|TrEMBL
MSLAAGTAPRVAGCPKSMAYGPCGGVNPDGTCEVDPTPCVFLRRDLPVRWDGNGDAPVDR
GPVDAVTTAAGREVAEIAQRRPLVFTGFPVRALRSDAVRPTADALSGSVDAVLSGDAGRS
RVQFPPSYRAALIAATGLRLWMGFNARDRNRTALERELLSLRALGVAGVHCVTGDHTQTG
DRADARPVFDLESTTMLPRARALGLLTSFAESPAAPPVAERGARVAQKQRAGGRLCLTQY
AGDAEEVADFVAQCRAAGATAPVLPGVPLVIDRDGAGLLASFHAAKLPRGFIDRLFAARD
VRAEGIRLAVEYGRALLDTGLVGGVVIAGGARLGEEVSYAADLATVARELGGGT
>A0A175Y2Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas melonis TY|TrEMBL
MTISVNQLEEAQIALKAPLYADVGGHLDVSFEFFPPKTEKMDEQLWEAVRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATRAEIDQVAEDYWAAGVRHIVA
LRGDPPAAGAKFESHPGGYENAAALVAGLKRLHPFEISVAAYPECHPDSVSVAADLDNLK
AKIDAGATRAITQFFHEPETFFRYRDKVAAAGITAEIVPGIMPVTNFASVVRMSKMCGTE
VPAWLARLFDGLEDHPAARQLVAATLAAELSRKLYAGGCKSLHFYTLNKAELSFAICHLL
GVRAKPMQDAAAA
>A0A0E3AWV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira borgpetersenii serovar Ballum|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTQDGDLKLMGTVKELARLDPDFVTVTYGAGGSTRDK
TAQILSEISKNYSFPTVSHFTCVGANQDQIFKTLKEIRSSGIVNLMALRGDPPKGEGKFK
KTEGGFENATELISFIRSEKLDFCIGGGCYPEKHPNAKSLEEDVRNLKRKVDAGTDFLVS
QLFFVNSIFENFLNLVRKANIRVPVIPGIMPITSFSQIERFRSIAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSIKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A090G4S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium plurifarium|TrEMBL
MTALQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAQRLDHILHDEITETQVDMVK
TAH
>A0A8D0UVX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKH
IRSEFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLK
ACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GQELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIV
DGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEES
PSRMLIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>C5GPB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces dermatitidis (strain ER-3 / ATCC MYA-2586)|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDTALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDDQDDPELLMEHLKEKVDAGGTF
IITQMFYDVDNFLTWVEKCRQKGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEAL
EPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQATKMILDELGLIPSHKTP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSLKELSEIFIRFLNGSLDRLPWSEGAVTEETEIIKSDLLD
LNRKGFLTINSQPAIDGMPSSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNS
DLTYYCVNKKGELKTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHAPSSLSRRLIEQVMDTWYLVNIVNNDFHKTHDIFNLFKDLKVENLDTEIEPIALAAE
SVDIAQQNGQLPQTEVNDSCTEATKSMEERNSN
>A0A292ZHJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium fuliginis (strain ATCC 27551)|TrEMBL
MTLSFPSVEEATRAWQAPLYADLTGDINVSFEFFPPKTEKMEEQLWSAIQTLTPLAPKFV
SVTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKGEIDEVIDAYWEAGVRHIVA
LRGDPPEAGAKFEPHPDGYKGAAELVEGLVKRHPFEISVAAYPETHPDALSAQSDIDNLK
RKLDAGATRAITQFFFEPDTFFRFRDTVAAAGIDADIIPGIMPVSNFAAVQRMSAMCNTD
VPGWMGKLFEGLDDLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPATLEKTA
>A0A6A5PLK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lupinus albus|TrEMBL
MKVIEKIVAAASDPERVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEISNRMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGLQNVLALRGDPPHGQD
KFVQTEGGFACARDLVKHIREKYGDYFGITVAGYPEAHPDVIASDGLAPPEGYQNDLAYL
KSKVEAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPVDIMAALEPIKDNEEAVKAYGIHQGTEMCKKILAHGIRNLHLYTLNMEKSALAILTN
LGLIEESKIYRSLPWRRPTNVFRIREDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSGS
PSYGALTDYQFMRPRARDKKLVEEWAVPLKSIEDIYERFKLYCLGKLRSNPWSELDGLQP
ETKVINDQLEKLNTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKL
DALVIKSKDRSSLTYMAVNKEGAWKSNVGPTYVNAVTWGVFPAKEIVQPTIVDPVSFKVW
KDEAFEIWSRGWAALYPEGDISRKLVEEVGSSYFLVSLVENDFVNGDLFGVFADF
>A0A509JA63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFENDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A2V6KH97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIIRGNSPTFSFEFFPPKTPEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVRHSQQEVEEILLRYAKSTIGNILALGGDRPVGVAYDKSR
DSFQHAIDLVKFIHRFNESGVHPDHRGFGVGVAGFPEGHPATPNRLLEMDYFKAKVDAGA
DYIVTQLFFDNRDFLDFRERCILANIHIPIIAGIMPITSISGLKRMAELAGGARFPSKLL
RALQRCQSDPEMVRRVGIHYALEQCHDLLDNDVAGIHFYTLNRSDATRVIFDSLGIPRRR
SAQASSV
>A0A8D0I168|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKH
IRSEFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLK
ACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GQELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKVRGPGVGLPCPPLGPWV
GRGAGSQVWDQG
>A0A8D1YN60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRSVGFQPTPDASLTPRAHGKGVKGGAPPGAPVQKETPRRFDRM
GAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEVTGYLH
KAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKGHPD
AESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACSEMGITCPILPGIFPIQGYH
SLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTL
NREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDE
FPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQELTSEESVFEVFAHYLSGEP
NQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGWGPS
GGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGI
FPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMLIQYIHDNYFLVNLVD
NEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>A0A345EGZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloplanus rubicundus|TrEMBL
MSLSKSKSTDGAPSLLAEPRFELMPFDSFEGQMEQLPEGAEIAITASPQLGLDATVEWSE
KSAARGYTPIPHVAARYVRDREHLDEIATRLTEAGVTDIFVPGGDREDPVGEFESAYDLL
VALDDLGHEFDEVGITGYPEGHDFLDDRTLAEAMERKAPYATYITTQLCYDPEAVLEWIE
TIRDRGVDLPIEVGIPGVMKYQRLLSISQKVGVGDSINFLRKTSGIVGFVRQLVGSRGKY
TPDALVDGLAPYVDDPDYGIRGIHIYTFNQTADTEAWRRERLDG
>A0A2V5JEB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRENSPTFSFEFFPPKTPEAAEMLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQRTTKLDPIPHLTCVCHNEREVEGILLRYAKSAIGNILALGGDRPAGIAYDKSR
DSFQHAIDLVKFIRRFNESGAHRDRRGFGIGVAGFPEGHPATPNRLVEMDYFKAKVDAGA
NYIVTQLFFDNRDFIDFRERCTLNDIHVPIIAGIMPITSISGCKRIAELAGGARFPAKLM
RALQSCQNDPEMVRRVGVQYALEQCHDLLDNDVAGIHFYTLNRSDATRVIFDSLGFPHHR
NARALSV
>A0A1X1XJI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium kubicae|TrEMBL
MQYGPCGGVRPDGQCEMRAGECAFPEVVPWSGSQYRTAPVQAPLVLTDFSCTPFDEADVA
ATAAMLAGSADAVLVGEHQNRPDFPPTLMGRLLLEVGASPWITLSCRDRNRVVLEQELRG
LQSLGLRTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASLGMVAAVPETPTAPPIHG
RPLRLVEKQRAGASLAVLNHVPYPQMIADFVSCARGAGLSIPIIAAVAVYTDAVSAAVLE
GLPGLELDHAVVDEVLHAADPIAAGISAAVTEARALLSIDGVEGVNLSGLASASGTRVGA
EIKAEVGRRIKEEAVS
>A0A0A7S3L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frischella perrara|TrEMBL
MKVNQLFKDKTVLSFEVFPPRKTSPLASIYGTLRELGHLKPDFISVTYGAGGSLNGETTI
NIAHAVKHTYGIESVAHLPSINFSKVEIKSILEELKLAGVDNILALRGDITPEVQPKQDF
RYASELVSFIKQHGDFNIIGACYPEGHTEATTVKQDLINLKEKVDAGTNQLISQLFFDNE
YFYVFRDKAADMGIHVPIEAGIMPVINKKQIERMVSICGVNLPKKFKQMMAKYEYHPEAF
RDAGIAYAIDQVVDLVSQDVDGVHLYTMNNSLIARRIHEAVASLFTIPKQIATQPVSA
>A0A8B7R6D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hipposideros armiger|TrEMBL
MVNEPGGHGGPNPRLAGSSIGRESSNVSSRCSKLPLSPERHERLRDKMRRRMESGDKWFS
LEFFPPRTAEGAPGFISRLDQMGAGGPLFIDVTWHVAGDPGSDKETSSMTIASVAVNYCG
LETILHMTCCCQSQEKITHLLHKAKQLGLKNILALKGDPVDDQWKDEEGGFHYAIDLVKH
IRSKFGDYFDICVAGYPKGHPDAGSFEADLKFLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFLIQNYHSLQQLVKLSKLEVPQQIKNVIEPIKDNDDAILNYGIEK
AVSLCQELLASGLVPGLHFYTLNRKEATIEVLKRLGMWIENPRRFLPWAVSAHPRRQKED
VRPIFWTCRPKSYIYRTQEWDEFPHGRWGNSSPSAFGELKDHDPFYLKSKSPKQELLKMW
GEELTSEESVFEVFTHYLSGEPNWNGCTVTCLPWNDKPLAAESSLKEKLLRVNRQGVLTI
NSQPNINGQSSTDRVVGWGPSGGYVFQKAYLEFFTSPQTKEALLQVLKNYEFRVSYHIVN
VKGENITNAPELQPNAVTWGIFPGREVIQPTVVDPVSFMFWKDEAFALWIKQWGKLYDEE
SPSREIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDTFELLSHPPRNDRETEAT
>A0A352PX41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacteraceae bacterium|TrEMBL
MAGSFRNALQSGQFVVTAEVGPPKGTDIEEMKEHIALLKDKVHGINMTDNQSSVMRLSSL
VGCHIIKQMGGEPILQMTGRDRNRMALQSDLLSASVLGIENVLCLTGDHIIMGDHKDAKP
VHDLESVQILRAARTLESGQDLGGNPLKGAPKFCVGAVVTPEADPIEPQLLKFEKKIRAG
AEFFQTQAVYDLDNFKRFMDYAGKFDVKILAGIVLLVSAKMATYMNEFVAGIQVPQKLVD
EMASAPKGGALQRGIEIAGRMVRQIKEQGLCHGVHIMAIGKETSVPAILSEAGL
>A0A0N1IEY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridioides difficile|TrEMBL
MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAANVTDFQSAVMRATSLA
TCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLLALTGDHTSVGDHPQAKGV
FDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTPEYSPIEVQLLKMQKKIKAGA
KFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSPGMAKFMTANVPGIFVPDEQIER
LRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIMAIGAEENIPAILDAAGL
>A0A0D2QEY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium raimondii|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DALVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFMVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A090VN75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jejuia pallidilutea|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPKKGKNIQDLYNNIDPLMEFKPPFIDVTTSREEYVYID
RGNGLLDKRITRMRPGTVGICASIMHKYNVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKEEAYFKPCEGGHAYASELVAQIAKLNRGKYLHDDVVVESNSDFCIGVAGY
PEKHMEAPSLITDLKRLKAKVDAGADYVVTQMFFDNSKYFEFVNKAREIGIDVPIIPGIK
PIAVKRHLQLLPQVFKIDLPQDLIDAVEACKDNKAVRQVGIEFAIQQSKELLDFGVPVLH
YYSMGKSDNIKAVAEALF
>A0A2I5HNI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella diarizonae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATGDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDIYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2N7HWI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio tasmaniensis|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A6H9SKD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia latens|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAQHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSDMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAASATRTICERLSM
>A0A381GG34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter amalonaticus|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGSGKPDMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGI
>A0A316ZLH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenophora tritici-repentis|TrEMBL
MEKITDKINSLPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCIGVAAYPEGHSDQSHPEHQDPLTDL
PYLVEKTKAGADFIMTQLFYDVQAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHARLPAEMLARLDAVKSDDELVKQMGVQIMDEMVEHIKARPETCRRGFHFYTLNL
EKAVSHVVEDTHLIPTTIMDDEEIIVETTPAINLEPPPNGLMARRRRSSAVNSGPFNRVI
ISHGSGAKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGYPVEKKDISTLFRRHIEGDLEAIPWSEQGLSP
ETSTISAQLLALNAKGWWTVASQPAVNGVKSTDPIFGWGPKNGYVFQKPFVEFFIPAAEF
QAFKPKLQAHDQVTWFAGNAAGAFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIWKEWQRIYPPQEWE
>A0A2P5L6K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacter sp|TrEMBL
MESQKKFSRSFSFEFYPPKSEEGAASLIKVHNELAQLKPDYFSVTFGAGGSTRDKTFESV
VAIQQKGIPAAPHLSCVASSRDSIREILKNYQTQGVNKIVALRGDLPSGMMSLGELRHAN
ELVALIRQESGEYFQIHVAAYPEVHPQAANAAQDLKHFKLKVEAGADAAITQYFYSPEAY
FHFIEACEIASIDIPIVPGIMPITNYSQLFRFSEMCGADIPRWLRKRLEGFGDDRQSIQA
FGVDVVSELCQRLLDNGAPGLHFYTMNQSAPTLAIWKNLQL
>A0A352JZN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSAPRVSFEFFPPKTPEAEASLWKTVERLAPLNPEFVSVTYGADGSTRERTHQVIESILT
KTELKPVPHLTCVGAPRDEIDAIADDYWSMGVRQIVALRGDPEGGAEADYQPHPNGYAYA
SDLVEGLLAKHPFELFVAAYPETHPQAISADTDLDNLKRKVDAGGHRAITQFFFDNAIFL
RFRDRVAAANINVELIPGILPVTNFNTLVRFADACGASIPATLKTLFEGLDEDPSTRQLI
AAHAAVSQAEDLGREGVSDFHFYTLNRADLSFAVCHALGVRGNA
>A0A7Y2JGV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella sp|TrEMBL
MKVTEHIENANGETLFSFEILPPLKGQNIDSIFDNIDPLMEFKPPFIDVTYHREEYIYKE
LDNGLLQKQVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFSKEDTENFLIDLDFLGIDN
VMALRGDAVKSETYFRPEKDGNEYASDLVEQIQRLNEGKYLDEELQNTSKTHFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKNGATYIVTQMFFDNAKYFQFVDKCRAEGITIPIIPGLK
PIATKKQLNLIPHRFSVDLPDELIMSVVKCKDNNEVRKVGVEWCVNQSKELIEKGVPLLH
YYSMGKSDNIYDIAKQIF
>A0A4L4DWX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCDNIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A4L7WSZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQYMQELAPYFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A5D2J4R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium tomentosum|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFDRMDRMVAHNPSFCDITWGAGGSTAH
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFIKFVNDCRQMGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQFPHGRWGDSRNPS
YGALTDHQFMRRRARDKKLQEEWATPLKSIDDIQEKFKSFCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSLSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGTTDVNAVTWGVFPAKEIIQPTVVDPASFMVWKD
EAFEIWSRAWAALYPEGDLSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>A0A0Z8VK76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A0N4XSK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nippostrongylus brasiliensis|TrEMBL
MASERTLVKFYSGLPHNHAILLSPIRFLSNIPQRSSNVCSYPLGHPEAPSYKADLQYLKS
KVDAGAQFIITQLFFEAEVFEQFVRDCREIGINVPIIPGIMPIMGYDSIRRIATLSQLTI
PESILSDLEPIKHDDDAVRKYGTIKVTFFRFQFGEACSAMESFISTSFDIVLFTSVLGVQ
>A0A5D2P958|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium tomentosum|TrEMBL
MKVIDKIQSLSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
NIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQVYKMFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELD
GLQPETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCS
LDKLDVLVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPAS
FVVWKDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>G8LL06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter ludwigii|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPHWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGA
>A0A2E6LPQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNQDSSSSARPRLSFEFFPPRSASGADSLSRVAGRLAELAPDFFSCTYGAGGSTRDGTRD
TIRQLLDLGLQAAPHLSIGADDQAQVFAMLDDYREMGVRRIVALRGDVPSGSGRSRFVHN
AETLVRWIREHSGDHFHLEVAAYPEVHPDARDAEDDLAHFAAKVAAGADSAITQYFYSPY
AYVDFVARCRAAGIEIPIVPGIMPITNYEGIIRFSEKCGADVPRWLRRRLASLQDDEQAL
RDFGVEVVTRLCEDLLAAGAPGLHFYTLNRWGASLAVCRNLGLDRQTGGR
>A0A451BJQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. SD|TrEMBL
MNPQGSNTQVFSFEFFPPKTPEGHNKLRATWQRLSRLNPHFFSVTFGAGGSTQSGTLETV
LEIQQHTGIDAAPHLSCIGSTRVKIQKLLEHYIANDIKRIVALRGDFPPDMVELGEFRHA
NELVEFIRAETGDSFCIEVAAYPEFHPTALSAAVDLKNFKRKVEAGANSAITQYFYNKDA
YFRFVDSCKRIGIDIPIIPGIMPITNYVSLAGFSQRCGAEIPRWLDWRLQEFGGDMKALR
AFGIDVLTELCYRLLEGGAPGLHFYSLNQAEPTMAIWKNLGLKVSAPDCSEIS
>A0A818UHB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MLLNQQKKGVSHYNTYQNDNGAEKISSSRFNNFKRSDSETRLLTAKGCCLESVEYISLTE
KIHERIANNDRWYSLEFFPPRTASGAANLIECFERMAVGQPLFCDIT
>A0A455B0K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Physeter macrocephalus|TrEMBL
MVNEPRGHGGPSPRWEDGTSGSESSKDSSRCSTPVPDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKRLGLKNILALRGDPTGDGWEEEEGGFSYAVDLVKH
IRSEFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
ALSLCQELLASGSVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGDNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLNRPPQGKRETEAP
>A0A354FQQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MAILSSLRASRPTLSFEFFPPKNDLGSEELLETVNELGKLDPAFVSVTYGAGGTTRERTR
EVVQRIIQDTNVPTIPHLTCVGHTKSEISEILSQYSADQVGTILALRGDPPRDQPNYDRE
GDDFKFAGDLVAFVKENSNEFEVGVAGFPEGHPETQNRLTEMDYFKSKIDQGADYICTQL
FFDNHDFFDYRERCNLVGIDLPIVAGIMPITTISSMKRMADLAAGSRFPAKLLKRLSVAD
GDAAAIRQAGIDHAIEQCQELIEQNVSGLHLYTLNKSSATREIANALTF
>A0A455B0J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Physeter macrocephalus|TrEMBL
MVNEPRGHGGPSPRWEDGTSGSESSKDSSRCSTPVPDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKRLGLKNILALRGGATLESGDTNPSVVKALPPRRTV
LGVGGEGTERLPGGRVRPSTVTSNPADPTGDGWEEEEGGFSYAVDLVKHIRSEFGDYFDV
CVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVKACSEIGITCPI
LPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQALSLCQELLAS
GSVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPK
SYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVF
EVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKP
SSDPIVGWGPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGDNITNAP
ELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYI
HDNYFLVNLVDNEFPLDSCLWQVVEDTFELLNRPPQGKRETEAP
>A0A349SLL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNSQQQHEKRFSFEFFPPKTDVGIEKLNLVQQTLAEKKPRFFSVTYGAGGSTRDRTFETV
NNVKNRTGIDAAPHLSCVGDTKAQLAQLLNQYQDAGINRIVTLRGDLPSGMGASLGELKY
ASDLVAFIREQSGDHFHLEVAAYPEMHPQAKSMDADLQAFKTKVRAGANSAITQYFFNVD
AYKFFVDSCEKMGLDLPIYPGIMPIINFDNLIRFSSMCGAEIPRWIRMRMECFRGDEQSI
KQLGEEIVTSLCEELLAMGAPGLHFYTMNQAEPTIAIWDNLNL
>A0A0V0W6T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella sp. T6|TrEMBL
LMASLEAVVLKATRHDLNSAAKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTTEGL
INLLKRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCILNFCLLDTMLHITSVQY
DEKTVLFNLERAKKIGIRNILALRGDISDDANVTTTDFQYACQLVRDCRKIGIVVPIIPG
ILPIQSYQSIMKIVQLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRKLLNREHH
VVPGLHFYTLNQEKSTRQKYTLVE
>A0A0F1D424|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter asburiae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1S7FVM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria weihenstephanensis|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARIAAPSL
EEIKRSFREQLYCLLLEGVDAILLETYYDLEELKTVLKITRETTDLPIVANVSMHEPGLL
QSGQTLASALQELADLGADVVGANCRLGPYHMSKALESVPLLENAYLAAYPNASLPQMDE
GKVVYQTETDYFEQYSEIFRQEGVRLIGGCCGTTPDHIRALRRGLKSIKPVTSKVVHPIL
ELAELDAAEDAGVRLTDKVKEQYTVLVELDPPRTFDTAKFFEGAQKLDAAGVDAITISDN
SLATPRISNMALAAILKQEYDIRPLIHLTTRDHNLIGMHSHIMGFHKLGIQDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALVDAGITVPVFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREADKSGTGREEGMAIAKEILDAICEHFNGVYIITPFLRYDLSIE
LTKYVQSKEKISEQTV
>A0A100JEB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces acidiscabies|TrEMBL
MTAPHPLFLDASLEMTGKDAPALEGAALAPGTRVNITHLASEDLDTRIDAARAVGKHGLT
PVPHLSARRLRSPAELGETLAALRSAQATESVFVVAGDPTTPHGPYPDALSVIRSGLLEE
HGVRHVGITGYPEGHPAIGTPALWSALEEKTAALKEQSLTATVTTQFGFAVEPVLTWLEE
ARARGIDVPVRIGVPGPAGVRRLVAYARRFGVSTSTGIARKYGFSLTHLMGTAGPDRFLR
ALAADLVPERHGEVALHFYTFGGLEATSAWLTGAATAPLPARSPRSRASRTTAG
>A0A5L1YT22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLGDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDDVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A374PBT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi|TrEMBL
MKIKDILGQGKPTLSFEVFPPKTEDKYESVEKAAAEIAKLNPAFMSVTYGAGGGTSQYTV
DIASTLHHEYQVTALAHLTCVSSTREKVHEVLEELKAAGIENVLALRGDIPKEGPVASDY
RFASELIREIKACGDFCIGAACYPEGHVESVSKTIDMDYLKQKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVVAGIMPVTNVKQIIRSCQLSGTYLPSRFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANGVDAIHVYSMNKPDVAAKIKENLSEIL
>A0A7K1BX89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKSDGAPTFSFEFFPPKDSEGESRLWSAIDGLRSIAPDFISVTYGAGGSTRDRTIKITSE
ITARTKVPTVAHLTCVGSTRVELLEILTKYREAGINSILALRGDPVGGPRAAWTKTDGGL
DHADELVTLAAEFGGFTIGVAAFPDGHPATDSTTDQDIEVLLRKEQLGASFATTQFFFEV
DKWVALVEKLAARGSSLPIIPGILPVTNVKQLNRMAELSGTPIPASISQAFDSVGENPDD
VRKLGVEIATELSQKLLDAGAPGLHFYTMNTSTATREIFENLKKR
>A0A2K4DN65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus devriesei|TrEMBL
MSRLLKQLHNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVERIHRSYIQAGADIIQT
NTYGANFEKLKAFGLEHKVKEIHKAAVQIAKRAAKPDTFILGTVGGFRGLKQEDLSLSTI
QYHAENQIDTLVEEGVDGLLFETYYDLEELSNIVTATRRKYDIPIIAQLTASNTNYLVDG
TEINEAFKQLIECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIAYIKSSVKDLKPVSDKKVIPINRKT
NHSRTHTYKHNLTTKVKNGPTVIVELDTPKHLDTDLFFENVGKLDEANIDAVTLADNSLA
TVRVSNIAAASIIRQKYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAVTGDPSKV
GHLPGASNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMSYFITQPVYSKEKIKEVYEATKHLNTPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQRVDYSLELTAY
SKAITQNKEAIS
>A0A6I3DFG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKIADALKAGPCYSFEFFPPRSEEAERNLATAIRELAPLAPAYVSVTYGAGGSTRDRTHD
LVVEILRDTGITPMAHLTCACHSRQELVDVVTRYRDAGIENILALGGDPPADSDQPPGEL
KYASELVDLIRGVGDFSIGVAAHPEPHPHSPSIEEDRRRTAEKLSKADFAVTQFFFDARH
YFDLVESLHELGVDKPVIAGIMPATSMRSITRMSELQGSEFPKDLAAKLEAAEPDGPEAV
HRVGVEEATRLCRELLDGGAPGLHFFTLNRSMATREIYEALGL
>A0A443KG62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinirhodobacter populi|TrEMBL
MTNTTDQKPQATNVPAVSFEFFPPQTLDASFRLWETVQALAPLRPDFVSVTYGAGGTTRK
LTHEAVATIHKNYGLTVAAHLTCVDATKAETMEIVEAYHQAGVTEIVALRGDPPKGAPRF
TPHPEGFASSIELIEALARDGRFTIRCGAYPEPHPEATDPLADVRWLKRKTEAGATSAIT
QFFFEPDTFFRFRDACVREGITAKLIPGVLPIQSWKGVKGFAARCGAHVPAGLESRFEAA
IRDGREQELSVELCVDLCEKLMAGGVDHFQFYTLNRPQLTQKVCAALGVTADRRLAVA
>A0A393A5H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNEGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDDVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A5R8LLE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus zeae|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNVALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDLEPVAHLPAAQLTRAQVDAELRGFQEAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQRGDFNVVAACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYRFRERTELAGIHVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIATATKTIRNA
>A0A3F3MJX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKKHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKVVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A1H9F727|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azotobacter beijerinckii|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLATARQLAGYRPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRSLLNTYKDAGIKRIVALRGDLPSGMGMASGELRHASDL
VEFIRAETGAHFHIEVAAYPEMHPQARSFEDDLAHFAAKMKAGADSAITQYFFNADGYFH
FVERVRKLGVEQPIVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFG
EQVVTDMCEKLLEGGAPGLHFYTLNQAEPSLAIWNNLGLPR
>A0A355AEI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKITDHIKNANGKTLFSFEIIPPIKGKNIQELYNNIDPLMEFNPPFIDVTTSREEYVYLD
KGEGLLDRKTTRMRPGTLGICAALKHKYNVDTVPHVLCGGFTKEETEYLLIDCHYLAIDN
VMALRGDSMKHQQYFEATKGGHVYATELVSQIQNLNKGKYLHDVLDAEHKADFCIGVAGY
PEKHIEAPSLQTDLKRLKEKVDAGADYVVTQMFLDNQKYFEFVEAAKNAGINVPIIPGIK
PIAVKRHMQILPQVFKIDLPEALILEIEKCKDNKQVRQVGVEWAIEQSKELLAAGVPVLH
YYSMGKSDNIKAVASAIF
>A0A1A6DXV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidimonas fonticaldi|TrEMBL
MALPLSFEFFPPKTPEGAAKLRAARQRLYAARPQFCSVTYGAGGSTQEGTLATVAEILAE
GMDAAAHFSCIGATRERVRAQLAELQRMGVKRLVALRGDLPSGYGLGGEFTYARDLVAFI
RAEFGAAFHIEVAAYPEMHPQARSPQADLQAFADKVRAGADGAITQYFFNTDAYFRFVDD
AYALGVEVPIVPGIMPITNATQLMRFSDACGAEIPRWIRLRLQGYGDDVASIRAFGLDVV
TDLCDQLRTAGVPGLHFYTMNQAEPTLAILQRLGMIGE
>A0A1X0X077|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. tigurinus|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2E8BGN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTFTDNSTSESPKEPKRRRPTLAKSDREVHRHLLEGMTFELIPLKSLDDQIRFVPTGSTV
SMTCSPNKTIEDTLDLCERLGNYGFSTIPHLAARMVEGEAHVDQILARITGLGIRKVLFI
GGDAEPHGPFTDAAAFLRSFLDRKPDIDVVGIGSYPDGHSTIPDDALVAALLEKQELIAA
AGLEGYMSTQMCFDHQKIGSWLADRRSAGVTLPCHLGVPGAVDRTRLLTISMRLGIGTSA
RYLKKNRTSVLRLLSPGGYNPNKLIAPLSKRATELGITGVHCFTFNAVDTTEDWRQKTLA
GLEC
>A0A099W1N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVAEQIISQN
>A0A162GKA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter tanaceti|TrEMBL
MSVHRSGTAADPACPSVPFSFEIYPPRTSGGAAALTRTVDRLAAAGPSFVSVTYGAGGSS
RGASLDILRYVREHTGTEALAHLTCAGSTPAQASRLVREFLEAGVTRFLALRGDPPADAA
EGEPFLGELGSAAELVQLIHRVQAEREPYGALPVPGLPHAQRVEVSARPHAQVAVAAFPN
GHPRSRSRTQDIDVLLAKEAAGASFALTQLFFHAEDYLRFVDRARAAGLRMPIVPGVMPV
TSPARLRRMLELSGEDVPAELAIALDVEPDDEARCRIGVDHAARLVRTLVDGGAPAVHLY
AFNRHEPVLAVLAESGLLPGSTSRPTALPPSTPSLQERTA
>A0A1W1DXH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKTSFEFFPPRTDKGKQTLAQVRQELSAINPEYFSVTFGAGGSTQDATLETVLDIQANDG
VSAAPHLSCIGSEKAKIIELLDQYKAADINRLVTLRGDIPSGVRDIGDFRYANELVEFIK
SEYNNHFHIEVAAYPEMHPQAKNIQTDLEHFANKIKAGADAAITQYFYNADAYFRFRDDA
QKLGIDVPITPGIMPITNHTQLVRFSNMCGAEIPKWILERLKLYENDLDSLTAFGTEVVS
NLCQTLKDQGVDSFHFYSMNRTEPSLSIAKNLL
>A0A853SRU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. HH102|TrEMBL
MEKHNFSIEFFPPKTLEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRASIRAVLADFKAAGVKRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGANAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>E2QIX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6D2KBV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microthlaspi erraticum|TrEMBL
MVQGSGRGKGRKMKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTF
CDITWGAGGSTADLTLDIASRMQNVVCVESMMHLTCTNMPVDQIDHALETIRSNGIQNVL
ALRGDPPHGQDKFVQVEGGFGCALDLVNHIRSKYGDYFGITVAGYPEAHPDVINDNGLAT
NEAYQSDLEYLKKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYK
GFLRMTGFCKTKIPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKSLHLYTLN
MEKSALAILMNLGMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKAWED
FPRGRWGDSRSASYGALTDHQFSRPKARDKKLQQEWVVPLKSVEDIQEKFKELCSGNLKS
SPWSELDGLQPETKIINEQLVKINSKGFLTINSQPSVNAEKSDSSTVGWGGPGGYVYQKA
YLEFFCSKEKLGAVVTKCKTLPSITYIAVNKGDTWVSNTAQTDVNAVTWGVFPAKEIIQP
TIVDPASFKVWKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIF
GVFADL
>A0A3V7IBS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Weltevreden|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A814HJF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sordida|TrEMBL
MEFTVSDNQAVPNNHKINGVETHLQSTCDLNGFKRIESEGANISAKGCCLQPIKYVSLKE
KILKRIADHDRWYSLEFFPPRTPSGAANLIGCFDRIAAGQPLFCDITWHPAGDPASNKET
SSMMIANTMLNYCGIDTMLHITCYGAKKANMLEYLYKAKDCGIRNLLALRGDPLVGEEWD
AEKSDFRYAVDLVKFIRQHFGDYFVICVAGYPQGHPDSTSYEDDLSYLKKKVDCGADLII
TQLFFQPETFLKFESDCRAIGITCPIIPGILPIQGFASLRNIVRLAKLDVPKEILACIEP
IKDNDEAIRNFGVQTCLDLCRTLLDSGKVDGLHFYTLNREFATIEILKKLGLWLEEQTLR
ALPWKKTSFSHARSKENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGALTDYH
LFYMKIDATRDELLDEWGRELTCEQDVWNMFACYVGGEKNSLNKVVRHFPWTDDELALET
GLIRKELVEFNSQGILTINSQPAVNGKPSLDPVVGWGTPNGYVYQKAYLEFFTNEGNIPA
LRAVLKKFPGVNYHFVNKSGEISETNADDEQPIAVTWGVFAGREIIQPTVVDPVSFMIWK
DEAFSLWTERWGKLYEQESCSRAIIDKIANTYFLVNLVDNDYPQGSCLWQILDSMFEYQK
LSNKHIDS
>A0A087SQI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Auxenochlorella protothecoides|TrEMBL
MSKIIDTLNAYIERGQPFYSFEFFPPKTDEGVRNLQERQRRMVKLGPAFCDITWGAGGST
ADVTLEVAGAMQQEIGMNTMMHLTCTNMSIEKLHESLEKAKSMGIRNILALRGDPPKGET
SFTAVDGGFACALDLVKYIRQEYGDYFGICVSGYPETHPDLIVDDPVAMEANYRSDLAYL
KAKVEAGADFIITQLFYDVDCFLAFMRDCRVEGIAVPILPGLMPLMTYGGFKRMTAFCKT
RVPAHIAATVEALKDNDEAIKAYGISLGTLMAQRLLDAGAPGIHMYTLNLEKSAVGILQH
VGLVKVEPEAEEAEEPQRLAATA
>K1EKY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janibacter hoylei PVAS-1|TrEMBL
MRNPREVLLFGITPPRAETAPERISEIAARTLARAEALPVDALVLYDITDEADRNAAPRP
FPFASMLDPGDYLSEQLAGWDRPAIVYRAVGKYREDELADWLAAAPDNVLTVFVGSSSSD
AEVNTTLPRALELHREVRPSLPLGGVTIPERHSGRGDEHERLLRKQHAGAGFFISQIVYD
IGAAKNLASDYRYAVVEDELDPAPLIFTLSLCGSDKTLSFLEWLGVRVPSWVRNEIVHAD
DPLKWSRQHALNAARELTDFCRYLGIPFGFNIESVSSRRVEIEAAEELTHEVAALLDRV
>A0A1W5QDQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus arlettae|TrEMBL
MTQLLQALKHNILIADGAMGTILYSEGLDTCPEAYNLSHPEKVEHIHRSYIDAGADIIQT
NTYGANFEKLKAYGLEHKVKDIHQAAVKIAQQAANDDTYILGTVGGFRGVRQEDLSLSAI
QYHTGIQVDTLVEAGVDGLLFETYYDLEELTNIIQATRRKYDIPIVAQLTASNTNYLRDG
SEINSALQQLKASGADVVGLNCHHGPHHMQQSFSHIELPDDGYLSCYPNASLLDIDNSEF
KYSDNAEYFGSVAQKLINEGVRLIGGCCGTTPEHIKFIKSSIKDLKPVTHKDIIPITKHQ
TKTTTTSSKVNLTTKVKQRPTIIVELDTPKHLDTSLFFRNIKKLDDADIDAVTLADNSLA
TVRISNIAAASLIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVDEILTITGDPSKI
GNLPGAMNVFDVNSKGLTEIAQRFNQGINTDGDALKQATNFNIAGAFDPNVRKLDGAIRR
LEKKIDSGMNYFITQPVYSKEKIKAVYEATKHLNVPFFIGIMPITSYNNALFLHNEVPGI
KLSEEILTQFEAVKNDKEKTRELSISICKELIDTVHEYFNGLYLITPFQRVDFSLELAAY
SKTITSTKQEAIL
>A0A5I4XHN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella muenster|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2N4VDJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella quasipneumoniae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A350V9L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIIDKLKEDRIHISFEVFPPKTNAGFDKVLRATNRIAELKPDFISVTYGAGGGTSKNTA
EIARHIKEDLGVESLAHLTCASSTKDEVINVIKNLKELGIENILALRGDIPENLSFPSED
RFRHASELVTEIHKNGDFCVGAACYPEGHPESQYSKEDIRFLKEKVDRGVDFLTTQMFFE
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQIKRSVELSGTVFPRRFLAIADRFGDCPE
AMQQAGIAYAVDQIIDLLANGVRNIHIYSMNKPEVAETIMSQLSEIVKC
>A0A3D1LTA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKFSDLMKKRQTLSFEVYPPKTEKGMNNLPGMIRRLGELQPDYISCTYGAGGSNVGKNRE
VLREVEKVAVPVTHLTCIGQTKESVRRQLQAYLDQGVTHILALRGDIPYGQNGTGGAFSH
ATDLVAFIRKEFGTAFEIAVAGTPGGHVECSSLEADIMHLRQKQDLGADYIITQLCFDMD
VFRRWYEAIRKAGITIPVDAGIMPVISKKSVISQCFSHNACPVPRDLALVLTHNWFDTDP
EGNEIPGAREAFREEGIAYTVRLLEQYIAEGIDGIHLYTMDRSEDVREVLQRAGLR
>A0A6B3L3S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mobilis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIKEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1D9LKD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium vaccinii|TrEMBL
MTQTPRTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGQAAAPHLSCIGSTRENIAAILNEYRGNGIRHLVALRGDIPSGMVAAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLANFVRKVRAGADSAMTQYFFNADSYFRF
VDEARARGVDIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRLRMQAYYDDTASIRALGL
DVVTELCDRLLQGGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A1B1K9M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus opacus|TrEMBL
MTFDSVRGRASEGWVTRTPSIVDRIRSSSDGRVPFSVEFSPPRDEAAEARLWRAVREFER
LGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWEKHPDGVEYAEDLVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSV
RRVLELSGSRLPAHLEKRLATAAGDGPEENRAAVREIGIDVATEMSERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSGVADPTPVTPARVS
>A0A7J0C4C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces fulvorobeus|TrEMBL
MALGTPSTRTDHARTVRELLASGKPSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATQRIAEDSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPRGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSADWETDIGHFVD
KCRAGADYAITQMFFNPEDYLRMRDRVVAAGCGTPIIPEVMPLTSARQLERFAQLSNASF
PSSLKERILAAKDDPTAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>B2B6X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383)|TrEMBL
MGEFLPSLELPVEAGKNHAMDKITDKIAALPAETNYCSLEFFPPKTAMGFSNLRDRLDRM
ARALRPLFVNVTWGAGGSTATKSLELAEICQRELSLTTCLHLTCTNMSRKLIDKTLEDAK
ALGIRNILALRGDPPRRAEYRDSNEPKTDDDEEEEFHWAVDLVRYIRKTHGDYFCIGVAA
YPEGHADESHPLGQSLEHDLPYLVEKVQAGADFLMTQLFFDIAAYDHFEKTLREHPSGAF
KDIVIIPGLMPIQSYQMIKRTTKLSHAKIPDALMDRLEAVRGDDERVKEVGVDIVSELVE
QIKEIKGRTAEGPKGFHFYTLNLEKAVSFIVERTGLIPPETPEEDELQSAVRHNPLPDIR
LLRINGSVPDDGRRKGSIGSDPRDRVIIQGRSTSYPDWEATAQEASIPAEPINSRANTLA
ISEGEGVLGREATWDDFPNGRWGDARSPAYGQIDGYGVSLHVTVAQALRIWGTPRTTEDI
NNVFIRHLKGELTTIPWSEEGFSPETDKIRDQLIKLNSKGWWSLASQPAVNGLRSSDPTF
GWGPANGFVFQKAFVEFFIPSADWKVLEQKLRHPDLKDDVCFYAINAAGDFVSSDTAGSL
EAEGEKEASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWGEWAKIYGKGSESEK
LLEKIRGDSWLVNIIHHDFIDSDAIWKVLLN
>A0A316Q1A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKISELLNQEKATLSFEVFPPKKDTDFENVERAASDIAALHPSYMSVTYGAGGSTKGHTI
QLAQSIQKQYQVPTIAHLTCVCADHKSIKTALDEMKNAGIENILALRGDIPKNYEGQVFT
DFAHASELAALIKEYGDFCVGGACYPEVHPDSSSRKEDILGLKRKVEAGCEYLTTQMFFD
NNIFFNFMYRVREAGITIPIIPGIMPITKKVQVKNAVKLSGCNVPERFKNIVDRFGDSEE
AMKQAGIAYATDQIIDLMANGVRHIHVYSMNKPEIAAGIQKNLSEILKA
>A0A0A2YQX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallibacterium genomosp. 1|TrEMBL
MSYAKEIDVLNRSIADLNGDINVSFEFFPPKNEKMETLLWDSIQRLKSLKPKFVSVTYGA
NSGERERTHSVVKAIKQQTGIEAAPHLTGIDASPEQLKAIAKDYWDSGIRNIVALRGDEP
PGYDKKPFYAKDLVKLLKEVADFDISVAAYPEVHPEAKSAQADLIFLKQKVEAGASRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFVQLQKMAKVTNVKIPSWMFKLYDGL
EKDQTTRNLIGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGIRPSLVA
>A0A350DHH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAARNPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRDETGDHFDIAVAAYPESHPQAPSLDKDVENFARKMNAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GTDVVTRLCERLLDGGAPGLHFYTLNQAAPVLKVVDNLS
>I1KG03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycine max|TrEMBL
MKIIEKIHAASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVVHNPSFCDITWGAGGTT
ADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVQHIRAKYGDYFGITVAGYPEAHPDVIESDGLATSEGYQNDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGINTLHLYTLNMEKSALAILMN
LGLIEETKVSRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALSDYQFMRPRARDKKLVEEWAVPLKSIEDIYERFRLYCLGKLRSNPWSELDGLQP
ETKIINELLEKINTKGFLTINSQPAVNGEKSDSPTVGGCKRS
>A0A3Z1V6J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6A3L1T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora rubi|TrEMBL
MGKISDSIRSAYAARADDASARPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFTDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGAERWAPVEGGLSNAVDLIKLIREEHGDYFCVACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIQWIADCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPESVLTALDAIKNDDAAVRRYGTQLAVETCQRLLAAGVNSLHFYTMNLATT
VTQVLEGLKMLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRTDLWGTPQTEQDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAAIRENLQWINSNGFLTINSQPRVNGAPSSDPSVGWGGDDGVVFQKAYVEFFVA
PEKMAHLVKVMRRDYPQLSFHALNRKGDEHRNTPLHSVTAVTWGVFPGTEIVQPTVVDSD
SFAAWKDEAFELWQTQWASAYPADSRSREVVQHIYDTYFLVNIVDNDYANDESDIFSIFT
RIITEAMDKEQLRARVLELETRREKMFDTLASFQSLQEELNGELRSVHSELAGVRSENLQ
LKEKVRQVQAQLALASL
>A0A6A3NS12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora rubi|TrEMBL
MKIIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMAEADIRKALDQAKAAGIRNILALRGDPVRGATS
FDECDRGFSHAVDLVRYMREHYGDHFCIGVAGYPEGHVESSDKKADVQYLKEKVDAGADF
VITQLFYDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTAFCNTFVPQEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRAAESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSSTSTPNERRAMWGEAPAAKEDIRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGVLSDDPMFGWGGLGGRVYQKAYVECFVSPENMKIIIENAAKK
PSVQYHAVNLNGHSYSNASKSAIAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEDGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSPATSP
>A0A656Z8Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sterolibacterium denitrificans|TrEMBL
MTSSTQGHPAPSFSFEFFPPQTPAGVDKLRAVRAQLAQFKPAFFSCTFGAGGSTRDRTLE
TVLEMQGEGHQAAPHLSCIGSTRENLRAILAQYRAADIRRIVALRGDLPSGMAVAGEFSY
ANELVEFIRRETGDWFQIEVAAYPEVHPQARSAAADLENFKRKVDAGADAAITQFFYNAD
AYDYFVEVAQRMGIDIPIVPGIMPIASYSNLARFAGNCGAEIPRWLAKRLDSCGDDVESI
RAFGLDVVTALCERLLKNGAPGLHFYTLNQAALTTEICRRLG
>A0A6J6J5K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MKSDGAPTFSFEFFPPKDSEGESRLWSAIDGLRSIAPDFISVTYGAGGSTRDRTIKITSE
ITARTKVPTVAHLTCVGSTRVELLEILTKYREAGINSILALRGDPVGGPRAAWTKTDGGL
DHADELVTLAAEFGGFTIGVAAFPDGHPATDSTTDQDIEVLLRKEQLGASFATTQFFFEV
DKWVALVEKLAARGSSLPIIPGILPVTNVKQLNRMAELSGTPIPASISQAFDSVGENPDD
VRKLGVEIATELSQKLLDAGAPGLHFYTMNTSTATREIFENLKKR
>A0A6J6KP30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSAGTAFDVSSATVQTPTISFEFFPPKDPEGEQKLWQTIDELQEFKPDFVSMTYGAGGGT
RDRTVRIAAEFIAKTGVPVIGHLTCVGSTRDELVDVLEQYKSEGFHGVLALRGDPVGGPT
APWVTTPGGFDYADQLVELAAEIGGFSIGVAAFPDVHPASDGNFAQDINVLLRKEELGAT
FAITQFVFDSGRYEALRNALDARGSKLSIYPGIMPVTSYPQIVKMLELSGGYMPKATRLR
FARYQNDPESLKQLGIDVAVQICEDVFALGAEGLHFYALNTAGPTAAIIKQLSMLAR
>A0A762XQL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSCEGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A442WEC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVAAAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
GSAAA
>A0A081JH82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus macedonicus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADIIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAREATGDDAFVLGTVGALRGLKQCDLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEAELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKETNFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDELANLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALKHFKGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A440BZD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFVDFGVTRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>A0A2V4ABL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium striatum|TrEMBL
MTPRLSASAPLDQFSEVSVEPRQRTALSFEVIPPRNDADASTTAELLRVLQGYNPDYIAV
TSSQRSGWLEGTAAFIEQISRTTSMRPLAHLACTAGTREELIGWIDALVDAGVRGLLALR
GDLPEGGMPAHYLQHADELVRLIRHREAGQAARFAAGSLAVGVACYPNGHAESANLDEDF
DVLLAKQRLGADFAITQLFFDAEDYARFAQRARLAGVRIPLIPGIMPMTSVARLERMAKL
SGLQVPPRVRAALAAASTPDEEHEIGMELTAELTRSVLRSGADGLHIYTHNNPHITQDLL
NRIGVHP
>A0A3D4Z6M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odoribacter splanchnicus|TrEMBL
MTKVIDIINQKKAPFASFELVPPLKGSDINKLYGAIEPLMEFAPPFINITFHRDEVEFRQ
TADGTFEKVTITKRPGSVAIAAAIMKRFPVEVVPHLICGGASKHQIENDLIDLNFLDIQN
VVALRGDAIPGQKYFVPEPDGHRYSCELVEQIHNMNRGIYLDECLKNAVPTNFCIGVAAY
PEKHYEAPNIDIDIENLKRKVDAGADYIVTQMFFDNTRFYEFAAKCRAAGITVPIIPGLK
PISTQTHIEMLPRAFSIDLPQELMNEVRKCKDNKAIYQVGIEWCTAQSKDLLAHGAPAIH
YYTMGKADNIREILKRTF
>A0A174QEP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides uniformis|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSIIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIREVAKQIY
>A0A085MAS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichuris suis|TrEMBL
MSLDSKEVSINGYASVEPLRPLRERIHDLIKAGDVFFSLEFFPPHTDVGLRNLYRKMERF
AEAGPLFVDITWSVRRDSASDQPNSSISVARSFRNMFLLDVVVHLTCVNCTTSQMEAYAN
KIRNMGVRNVVALRGDTTTKPSLSSMKYANAVQLVQLLRFKHGDYFTIAVAGYPLGHSEA
VSFDEDLKFLKRKVDEGADVIITQFFFSSKSYFYFVRRCRDMGITVPIIPGIMPLHDFEG
YKKTCSMCGMVMPTWMCQMFEPIQEDAEAVKNLGIHLAVKMSQELLGHTFYRAPSLHFYT
LNQEEPTKTILKRIGMWQTIGRSILPWKVNPTQAIRRSERVRPIYWKNRPKAYIFRTKHW
ILYPNVNWTYRSDIQLSDLEGYQLFDPLRAISRKRLLEMWGASLQSMDDINAVFFSVVSG
RPNANGIVVEYFPWSESKLKCSVLPPVDDLLWCASNGILLINWQAAVNKVPSGTVEIDDA
SFGWGELGGHAYLEFFASPTFVHSLLSIIAKYPMVSYHVINRDASFEKTNAPSLVEANVV
TWGIFPDNQCIQPYVTHPMAFRQWKDEAFNQWKMWEDLYKPHSSEHSLFSEIYDQYKLVS
LVDNDYTNPTSLFKLLKDAIAEPVKLSV
>A0A3S3KIB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRANLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A1I3LVB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas argentinensis|TrEMBL
MSQKHPNVSFEFFPTKTDAGHEKLLNTARELAAYNPDFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDSKAELIELLNLYKSKGINRIVALRGDLPSGMGMSSGELRHAND
LVELIRAETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGANSAITQYFFNADCYF
YFVERVRKLGVDIPVIPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDTQSIQRF
GEEMITGLCEQLIAGGAPGLHFYTLNQAAPSLAVWKNLQG
>A0A857LNE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia amarae|TrEMBL
MTTNSTSPSIVDRLSAPHRGRIPFSVEFMPPRDAEGEERLWRAVRTFERLGPAFVSMTYG
AGGSTRDRTVRITGQLAAETTLLPVAHLTAVNHSIDELRSLVGAYAAQGITNILALRGDP
PGDPLGEWVRHPRGLTYAEELVRLIRDLGDFHVGVASFPEGHHRAPDLRQDTQALVSKLR
AGAEYSITQVFFDVEHYLRLRDRLAAADPEQAAKPLIPGIMPITSLASVRKMVSLSGSVI
PVDVEARLAAAAGTGDQEDRAAVRAVGIDLATEWAERLIAEGAPCLHFCSLNFAKASTEV
LARLGVDVTAAVPATT
>A0A6G3Y007|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7499|TrEMBL
TPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDPAAVRSIGIEFATEFCAKL
LSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A518BWB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucisphaera calidilacus|TrEMBL
MHITDILANRKTAFSFEFFPPKTQAAAESLYQTIAELEPLRPDFVSVTYGAGGSTRELTH
DLVLRLKKTTSLDPIPHLTCVCHQASEIAEIIDQYAAEGVSNILALRGDPPRDKADWDRS
KDAFQYASELVTFIREHASHTQHPDPRGFGIGVAGFPEGHHATPNRLREIDYLKAKVDAG
ADYICTQFFFDNRDFYDFRERCDLAGIHVPIIVGLMPITSMKGMNRMAELSPGTRFPAAL
IRSLQRAGDDAEAVKRVGIHWATEQARDLLDHQASGIHFYTLNSSDATRQIYASLGVASP
S
>A0A8C4UXN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falco tinnunculus|TrEMBL
PSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDAGDKWFSLEFFPPRTANAA
VNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQ
TKDDITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDIC
VAGYPKGHPEAESYEADLRHLKEKVLAGADFIITQLFFRSETFLKFMKDCQAIGITCPII
PGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSG
MVHGLHFYTLNREVATTDVLKRLGIWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKS
YIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFE
VFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNINGKPS
TDPIVGWGPSGGYVFQKAYLEFFTSSEIVMALLKVLKKYELRVNYHIVNVKGQNITNAPD
LQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIH
DNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQE
>A0A7X9DTG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MSKLSEALARGEFVVTSEVGPPKGTRVDELMAKAALLARWTHAVNVTEQQHSCMKLSSLA
ACALLCQRGVEPIVHAVCRDRNRVALQSDLLAAWALGIRNVLVLTGDHPRMGDHPEALPV
FDLDSVQLLLAVQRLNQGFDLAENPLEGATDFFAGAVVNPTSDALELQLIKMKKKVEAGA
RFFQTQAIFAPERLEAFMERAAPLRVPVLAGLVLPKSHTLARFMKEKVPGMYVPDELIAE
LSTVPKAERRQKAVEVAARIIRRIRPVCQGVHIMALGWEELLPDILAQAGLREKPWEDPD
NPHIPE
>A0A2R4L9C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira santarosai|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSRLDPDFVTVTYGAGGSTRSK
TAQILSEISKNYSFPTVSHFTCVGANQEQILKTLKEIRSSGIVNLMALRGDPPKGEGQFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPNAKNLEEDVENLKRKVDAGADFLVS
QLFFVNSIFENFLNLVRAAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A833PJX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bereziniae|TrEMBL
MLLTGDKLKQQHDGQGQHARTRYLESVNAVMAAQQYGGFHIGVAFNPFKYTPAEQQAQYL
KLNKKLNAGADYIITQLGFDLSALKQLQTFLAQEKYIQKTLACVMPLTLARAQFMVKHKV
AGIVITPHMLEVLAQDQVNQCSENAYKRCALQILICQHLGYAGVHLSACHKTDEQMLLEQ
YIEQYRDLNLSQCEMLWNQLWQLAEGEQIRPKVAVKRIKSALNNKVKYQFLDLIHRAMFQ
SSFVKGIGTFIFNASFWNRKAAAKVLLQTEYLSKHYLLGCESCGQCRLAETLYICPETCP
KGLANGPCGGTDLDRCEFGDRECIHSVKSRLARDVDQIQLLKEQLIPTVPIEVRGTSSWK
NWYKAE
>A0A1B1N0Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus yonginensis|TrEMBL
MTDLRKALESKILIGDGAMGTYLSQLGHPVGISYDELNLVSPEAIREVHTQYIQAGASVI
ETNTFSANAYKLSKFGLESKTAEINRAGVRIAREAAAGTSAYVIGAVGSIRSGRRINVSA
RELGLYFGQQIDALLEEGVDGILLETFFDLEEMEIAVKCIRERANVPIISQFAVDQVGRT
LDGYAITDAFSILKQEGVDVVGFNCHSGPQGIMSVIQQQLPVPLEIPLSVYPNAGLASFV
DGKYVYRATPAYFGERAKDFAAVGVRLLGGCCGTTPEHIAEMAKALADYVPQPLAAAPKL
PRETVSVIRQLNGKAGEPSAGGTEGTEAPTLVDLVKQRPTLIVELDPPRDLDITKFMEGA
AALKEAGVDAVTMADNSLAVARMSNMALGHLVQERIGLRTLAHIACRDRNLIGTQSHMMG
FDALGINHVLAVTGDPSRFGDLPDASSVYDLTSFQIIKMIKQLNEGIAFSGKPLKHKAKF
VVGAAFNPNVKHLDKAVQRLEKKMASGADYVMTQPVYDPELIVRIKEATAHLDIPIFIGI
MPLASGKNAEYLHNEVPGIELPESIRARMSGLSGEAGRLEGVEIAKELLDAAMEHFNGIY
LMTPFLFYEMSVALAKYVQEKSKERASYLFHS
>A0A8B9K6F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Astyanax mexicanus|TrEMBL
STVILEYNCKISSDSSGGSNSGESSKESSRCSTPVLDTDRTDRLRDKMRRRIESGDHWFS
LEFFPPRTAGGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LESILHLTCCKQTKEIITAHLNKAKRLGLKNIMALRGDPIGADWEEEEGGFNYATDLVKH
IRHEFDDYFDICVAGYPTGHPEAESYEDDLKHLKEKVDAGAHFIVTQLFFRAETFLKFVK
DCRAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGIQQ
AVEMCRVLLASGDVSGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKVED
VRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSSKEALLKMW
EEELTSEDSVYQVFTNYITAEPNKSGHKVMCLPWNDDPLAPETNMLKEELEKVNRRGVLT
INSQPNINGKPSSDPVVGWGPPGGYVFQKSYLEFFTSSENVNALLKVLKKYEPRVNYHIV
NVKGKNITNAHDMQPNAVTWGIFPGKEIVQPTVVDPVSFMYWKDEAFALWIEQWGKLYED
ESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIDDMFELLDAPPEPLDQENLQ
>A0A4Q5X8C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MRIVEKLGGSRAAISFEFFPPKDQEGVDRLFKTVAELAPFAPSYVSVTYGAGGSTRQLTV
ELVGRIQREVGIDAMAHLTCVGATREELGGVLDQLEAAGVQNVIALRGDPPQGATSFMTP
AGGFGHASELAAFIKGRGTFCIAGACYPEKHPEAVSLESDLERLKHKVDAGAELLITQLF
FDNADYFSFVERARALGIRVPIVAGIMPVTNVSQIKRFTAMCGARMPGELMQRLETVAAD
PEAVGEIGVQHAVQQCRELLEGGAPGIHFYTLNRSKATVEILKRLR
>A0A431NYW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobiaceae bacterium|TrEMBL
RPSISFEFFPPKTEEMEQNLWGVINRLAPLSPNFVSVTYGAGGSTRERTHSTIKRILEET
SLTPAAHLTCVDATCADIDDVVDRYHEVGVRHIVALRGDPSGGIGTVYRAHPEGYQNSSD
LVASIKRRHPDMEVTVSAYPEKHPESATIDADIDVLKAKVDAGADRAITQFFFDNDLYFR
YLDHVRAAGITIPIVPGILPVQNFKLAKNFATRAGATVPDWLAEKFEGLDDDAETRKLVA
ATVAAGQVQKLAKHGVENFHFYTMNRADLVFAISHLLGIRPNGSQQAA
>A0A524L8V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MRIAERFATGRPAFSFEFFPPKTEAGFDALFETIRDLKPLGPDFVSVTWGAGGSTRRKTV
ELVIQIQREVGLTAMAHLSCIGSSPEELAATLDLLASGGIENVLALGGDRPRDYAPPPGA
FSFANELVAFIRSRWDFCLGGACYPETHPLAAGPEEDLRNLAHKLDAGLDFLITQLFFDN
ADYFAFVERARAAGIRVPIVPGIMPIVSVAGIRRMTSMSGAKIPDELAASLAPIEHDDDL
VRALGVEWATLQCRELLERGAPGIHFYTLNRSSATRAILQQLRRE
>W4TVT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium acnes JCM 18916|TrEMBL
MVSTGLRTVGHLTCVAQSVADVEQMVADYAESRIDHILAIRGDMLGGAGQLGWPIPGGYL
TLLSLSASSSGFTQRHASVERVRDMGCELFNVGALGLHHYTLNRSRATTELRTMLAWRRL
ERAGSPRNDEAIFLLPEPDYR
>A0A1Z4I1A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. NIES-2111|TrEMBL
MDNNHSCTALNYFSKAAQAGEFLVTAEVAPPKGGNPSHMIEMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQQGIEPICQMACRDRNRIALQADLMGAHALGIRNILALTGDPVKA
GDHPEAKAVFDLEAVRLLQLIRKMNQGVDCNDKPLTDGATDLFVGAAVDPQCASWSGLQS
RFERKIEAGAQFFQSQLITDFERLEKFMDKMASVYNKPILAGIFLLKSAKNAQFINRCVP
GVNIPEHIINRLAKAKDPLEEGVKIAAEQVQTARQLCHGVHMMAVKREDLIPKILDLAGV
APVHQVLVR
>A0A4D7QT33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phreatobacter sp. NMCR1094|TrEMBL
MSSSAYRPSRYVSASRLKVSFEFFPPKNEEMEQTLWESVERLAPLNPSFVSVTYGAGGST
RERTHATVSRIVKETALKPAAHLTCVAATKDQVNEVIRDYWAAGVRHIVALRGDPVGGVG
TAYTSHPGGYEGSPELIAGIKAIGDFEVSVSAYPEMHPESGSVERDIEMLKRKVDAGATR
AITQFFFDNDLYLRYLDRVRAAGINIPIVPGIVPVQNFKQTAGFAARTGASIPDWLAKRF
EGLENDPATRKLIAASVAAEQALDLVDRGITEFHFYTMNRADLVYAVCHLLGMRPEAAAA
KAEAA
>A0A5C6Y3C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. IC066|TrEMBL
MKITEHIKKANGKALFSFEVIPPKKGNNIQELYNNINPLMEFNPPFIDVTTSREEYVYVE
KEGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFSKEETEYLLVDCHYLGIDNV
MALRGDAMSHQKYFVPSKGGHNYAKELVAQIQNLNCGKYLHEVMEAASKADFCIGVAGYP
EKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVEAAKNAGIHVPIIPGIKP
MAVQRHLQLLPQVFKIDLPETLINSVEKCKTSKDVRQVGIEWTIQQSKELLAAGVPVLHY
YSMGKSDNIHAIAKELF
>A0A0B2JXP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerovibrio lipolyticus|TrEMBL
MGRISVELIPRSEDGLRDDLQIVKKNAPGVELINIPDLLRFDMRSWQGAAIAQEYFPAVM
PHIRAIDVDLSQPLSMRPELRQSGITEVLVIEGDPPQDMSHKFYPTVTTDVISKFHQEMP
EVKVYAGIDQYRGSMRQELYRIQRKLQAGAVGFFTQPFFDIRFMEMYADMLEGQNVYWGV
SPVMSERSQSYWELKNNVIFPKGFQPTLEWSIEFSKKALKFAEERDANLYLMPIKSNLEA
YLQGVLG
>A0A1H7HUC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atopomonas hussainii|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLNVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLNTYQSNGIQRIVALRGDLPSGMGMASGELRFANEL
VEFIRAETGDHFHIEVAAYPEAHPQARSFETDLNNFVRKMQAGADSAITQYFFNADCYFH
FVECAEKLGVTQPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIDSIQAFG
EEVITAMCERLLQGGAPGLHFYTLNQAEPSLAIWHNLKLPR
>A0A653V8H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. 62|TrEMBL
MNAFRPSRHGSRRPRVSFEFFPPKNEEMEVNLWDSVRRLEPLGPAFVSVTYGAGGSTRER
THNTVKRMIDETALKPAAHLTCVSASCAEVDDVIRSYWAAGVRHIVALRGDPAGGLGTTY
EPHPEGYHQTSDLVEGIRKIGEFEVTVSAYPEKHPEAASLDADIDALRKKVDAGATRAIT
QFFFDNDVYFRYLDKVRASGIDIPILPGIVPVQNFKQTAGFARRTGASVPQWLADRFEGL
EDDAATRRLVAAAVCAEQVLDLIDRGVSDLHFYTMNKADLVYAICHLVGLKPEKAQAQQV
AAE
>A0A8I1T309|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus sp|TrEMBL
MTERTFSFEFFPPKTTEGAEKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETVCEIQA
SGSEAAPHLSCIGSTEASIRDILNAYKRQGIRHLVALRGDLPSGTMNAGEFNYANELVAF
IRKETGDWFEIEVAAYPEVHPQARSATEDLANFKRKVDAGANSAITQYFFNADAYFNFVE
DARALGVAIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLASIRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPSTTIWQRLGL
>A0A7X6TIY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MQIPQLITGRRPFVSLEFFPPKNRDEWPAFVDAARELSQLRPLFASVTYGAGGSTQDNTL
EICERLIDACGFEIMPHLTGVTADRAKIDGFLESIRALGIDNVLALRGDRPAGFTGTDEE
LFAVFPHAADLVSYIRARQPQLAIGVAGFPEAHAEAPSFSADLAVLRHKVDCGANFVITQ
LYFDNRVYFDYVERLRALGVTVPVIPGVLPIRSLASLRFTLQLCNARVPGQLINSIIQAH
ERSGAAAVYEIGVAYAREQVRGLIEGGAPGVHLYTLHRADMCLAVMDGLF
>A0A8E3B424|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium loti|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETAIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFRQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHDAEAA
GSAAA
>J2T2T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM50|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A0S2PA55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces hygroscopicus subsp. limoneus|TrEMBL
MDPALLDDFSLEMTGKDVPGLEEARDSIPPGTRINITFLAGEDTGTRLSAARAVQRLGFV
PVPHISARRLPSRTALEEFLAGLAADGTAGNVFVVGGDPARPEGPYEDALAVLRTGLLRR
HGVRHVGIAGYPEGHPGIADRLLWPALTDKAAAIGADRFTGDVITQFGFDADPVLAWLEA
LRARGVHLPVRVGVPGPAGVRRLLRYAGRFGVGTSASVARKYGLSLTNLMGTAGPDRFLH
ALSDRYDPARHGTVKVHFYTFGGLRTTADWIARFRHGSERISEERQTTRS
>A0A3S4TYT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium varium|TrEMBL
MKISELFKRKKTIVSFEVFPPNSIYSLEDVYSSIDELAKLQPDFISVTYGAGGATRGNTV
EIASKIKNNNKIEALAHLTCLGAKKNEIDDILKQLRANNIENILALRGDKPKDSTPIGEG
DFKYAQDLISYVKEKREFSIGGAYYPEGHLETNDLLDLFNLKRKVDSGTDFLISQIFFDN
ESFYRFRDKLNKLQINIPLVAGIMPVTNAKQIRKITSMCGCSIPEKFQKILNKYENNTQA
LKEAGTAYATEQIIDLITSDIDGIHLYTMNKVDTAKKIMANIAHIREISGGNR
>A0A3D8H2S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter flavimaris|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYREHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A1X6Y7Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius halotolerans|TrEMBL
MPTPRVSFEFFPPKSLEASFRLWDTIHTLAPLDPRFVSVTYGAGGTTRELTREAVGTLHK
ATGLNVAAHLTCVEATREETLAIADGFHQAGVTEIVALRGDPPKGSDGFTPHADGFANSC
ELIEALADTGNFTIRVGAYPEKHPEAADTKADIEWLKRKIDAGASEAITQFFFEAETFFR
FRDACVKAGIDAPIIPGVLPIENWTGVRKFATACGTGIPAWLDDTFDKALRDNRQDLLAT
ALATELCSELIEGGVEDLHFYTLNRPELTRDVCHALGVSPKVSLRDVA
>A0A2N6C9G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MNLKTESKLEKILAAGHLAVTSECGPPRGSDPEVIKKKGELLKDYVDAINVTDNQTSVTR
LSSLAACIHLKLMGVEPVLQMVTRDRNRIALQSDILGAASFDINNILCLSGDHQVFGDCP
GGQNVFDLDSMQLLQTVRHMRDNGKFLGGDEINRPPRMFAGAAANPFAEPFKIRVPRLAK
KIAAGAEFIQTQCIYNLDRFEEWMKGVCDRGLHEKVYILAGVTPMKSLGMARYMKKNVPG
MDVPDEVIDRLAGVPKEQQAEEGMKICLETIERLKEVKGVSGFHIMAIEWEEKVPEIVER
AGLFPRPE
>A0A366FPE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseiarcus fermentans|TrEMBL
MPVKPVPLSRSRAPVRVSFEFFPPKTPEMEANLWEAARRLEPLDPHFVSVTYGAGGTTRE
RTHATVARLARETTMKPAAHLTCVGASKAEIRDVLAAYHAAGVRHIVALRGDPPTGIDAP
YEAPPDGFQTTEELVAEARRVGDFEVSVGTYPEKHPQSPTLLHDIELLKRKIDAGATRAI
TNLIFDNSAYFRFLDVAAAAGISIPIVPGIFPVQNFKQTANFARRSGASVPQWLADRFEG
LEDDPATRRLVAAAVCAEQVLDLVDHGVGELHFYTMNRADLVFAICHLIGLKPGPKVEAA
AA
>A0A374G4T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM28-29LB|TrEMBL
MKISNLFNNGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYGAGGNGSKNRT
CEIASKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>X6DI81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNHC221B00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A1B7X8W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halodesulfovibrio spirochaetisodalis|TrEMBL
MKIIDAIQSQSKPFYSLEFFPPKEKKQWDSFFSTVERLKALNPLFASVTYGAGGSTQDNT
LEITSRMKHVAGIEPMAHLTCVGASREKINGFINKLREADVHNVLALRGDCPPDENFSWT
DQEFRYASDLVTLVSKEHPDFGVAVAGYPAAHPESPTFADDLHYTRVKIDAGSDFVVTQL
FFDVREYFDFVSRLRSNGINKPVIPGILPIQSLNSIKRILSLCGANIPGQLYLTLEEANE
KGGDEAVKEAGLKFAVNQIRQLVDGGAPGIHLYTLNKADMCLELADRVNL
>A0A354EC38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKSGSNLERVLTSGGFAVTGELGPPKNSDPEVVRSKARLLRGNVDAVNITDCQTAIVRMS
SIGAGLIAQSEGVEPVIQMTCR
>A0A4Z1I9G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryotinia convoluta|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDSPRSEE
YRAIDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDGFEQKLRDHPSGAFKNIPIIPGMMPIQSYQMI
KRTTKLSHAKLPSTIITRLDAVRGDDEMVKKVGVDILSEMVEHLKSTKSQYSGPRGFHFY
TLNLEKAVSFILERTELIPDAETVAALEPEYVPTIPDIADLMSIHSGSHKRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETYSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGPKNGFVFQKAFVELFL
PTADWKTLHAKLTSPELRDTVSFYASNAKGDFISSDEAVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSQTRKIIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLN
>A0A370PI89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus phoenicis ATCC 13157|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVEQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A1G8H7X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea jiangxiensis|TrEMBL
MPTVRDLLASGGHTFSFEFFPPKTDEGERQLWRAIRELESLRPTFVSVTYGAGGTTRDRT
VDIVERIAHETTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVRGDPPGDPMGEWV
RHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTEYFIRKCRAGADYAITQ
MFFEADDYLRLRDRVAAAGCDTPIIPCLMPVTRMSTIARSEQLSGAPFPAGLAARFEAVA
DDPAAVRRLGIDHGVEMCRRLLAEGAPGIHFITFNQSSASREVFQRLDGIAVSA
>A0A671KK82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus anshuiensis|TrEMBL
MIYEYKHTCWRSSKSDSSGVSNSGESSKESSRCSTPVLDTDRLQDKMKRRIESGDHWFSL
EFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVNYCGL
ESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLVKHI
RCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDSGAHFIVTQLFFRAETFLKFVKD
CRAVGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRSYGIQQA
VEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKVEDV
RPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWG
EELMNEESVYEVFTNYITAQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGVLTI
NSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVN
VQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDE
SPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFALLDSPRETQEGSQS
>A0A7Y4CSC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. T3Y01|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPPGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>R6TC36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides coprophilus CAG:333|TrEMBL
MRVIDLITSSEKTAFSFELLPPLKGTGIERLYGDIDKLKEFDPKYINITTHRSEYVYQEL
GDGLYKRRRLRRRPGTVAVAAAIQQRYGITVVPHMLCSGFTREDTEYVLLDLQFLGITDV
LVLRGDKARHESAFVPEPGGNAHAIELEEQINDFNRGIFVDGSPIRAPHTPFSYGVACYP
EKHEESPNAEQDLLWLKRKVETGADYAVTQLFYDNNRYFSFVKRAREAGITVPIIPGIKP
FSKLSQLTMVPKTFKVDLPDELAREALKCKTDEEARALGTEWCIHQCRELMAGGVPSLHF
YTVGAVDVVRDVAKAIF
>A0A7G8EJQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp. NS01|TrEMBL
MLLQQALASGQPAITAEVTPPRGADPSRTLAAAAALRHWVHAINVTDGSRAVMRMSSLAL
CRLLLDIGLEPVLQMACRDRNRIALQADLLGAHALGLRNLLCLTGDPVRAGDQPGARPVN
ELESVRLLQLVAQLNSAQDPVSGLLPDGGTAFFAGAAADPQSPSWSGLQSRMRRKQRAGA
RFVQTQMVTDATALRRFVDEIAAPLGLPVLAGVFLLKSAKNALFINRVVPGANIPQRLID
RLAAATDPAAEGVAIAAEQVASYLEIAQGVHVMAIKAEALIPRILAQAGLAPLQPAAGLE
HGDHGLSAAPPAPAPAAVALGREVSS
>A0A838S7M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MTAVSDRIGGDRPVFSVEFFPPRDDAGESALWRAVRELETTDPAFVSVTYGAGGSSRDRT
VRITGRIAQETTLVPMAHLTAVGHSVAELRHVIGSYAAVGVRNVLALRGDPRGGPREEWV
AHPQGFSHAADLVRLVRGLGDFCVGVAAFPEGHPRAPDLDTDVAHLVTKLRAGARFAITQ
MFFRTEDYLRLRDRVAACGADMAEVPILAGIMPITSAKGIERMAELSGAVIPAAVRDRVE
AVADDPAAVREIGVDVATALAERLLAEGAPGLHFYTLNRSRSTREVLGRLGLLPVQAL
>A0A497ITP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon|TrEMBL
MKKIKEGKFVFTGELEPEKTTDLTELVESAKKLLGHCVACNVTDNPQSMAYMSSLVASYI
VQRDSGMECVYQLRCSDRNSIALTSDLLGAGALGIRNVLALTGDHTSLGDYPGSMPVFDL
DSGQLVYLIRRMVDEGVDLNGKPIEHPPRFHVGVAGNPNADPLDSEILKLKRKVEAGAEF
VQTQVIFDIEIAKTFLKEMEKYKVPVLIGIFPLKNYGTADYFDKYIPGVHVPKDLLAKMK
EASEIGDKKKKMERYDEINLDYYGDFVHEIAHNTSAA
>A0A7C1BX41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
KSAGMANFMNKNVPGIMVPQDLIDEMKAAGKEKALDTGLNIAARHIRQLKEEKICDGVHI
MAIGMEDKVPEIMERAGLL
>A0A7M5V507|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clytia hemisphaerica|TrEMBL
MERIKEKLNPEKMVQNRPENATTEDGQNYVSLTDRINQKIKDNEKFFSLEFFPPRTPNGA
VNLIARFDRMSRGGPLFCDVTWHPAGDPAGDKETSSTTIASIAANYCGIQTMLHMTCANL
TKETVVKNLTKAKNLGLRNILALRGDPVNGEEWKSFDDSLNYGSDLVKLIRQHFGSYFTI
CVAGYPNGHPDATSYEDDIIHLKEKVDAGADFIITQLFFKTEDHLKFVRDCRQAGITVPI
LPGVMPIQGYASLRQLVKLSKLEVPQEIMDVLEPMKNDDEAIRKYGVKQATEMCRELLQS
DDVPGLHFYTLNREVATIEILRNVGLWKKYQIHRPLPWKHSAHTKRIKEDVRPIFWAIRP
KSYVHRTSSWDEFPNGRWGNSSAPSFAELTDHHLFFLRSPKGKESRNKMWGNELESLQDV
YHVFQCYLSGQKNKWGNKVTALPFNDEEIQTETSVLLEQLDRINGEGFLTINSQPNVNGV
PSDNETFGWGGSGGYIYQKAYLEFFMPKKYIKALRLVLKDLPQVNYHIIDNQGYVDDTNA
DRYQPIAVTWGVFPGKEIKQPTVVDPISFNFWKDEAFGLWKIQWQSLYEEGSASANVIES
ICNDFVLVNLVDNDFIKGNCLFDIIEKTIEISPTLSPTVEEELANEKASFQFESSDDEQR
VTSPINEQTSPQLAV
>F6EFE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoyosella subflava (strain DSM 45089 / JCM 17490 / NBRC 109087 / DQS3-9A1)|TrEMBL
MRQTGVRGMRPGRTPSIVERITSDPRSTPFSVEFYPPRNEKEEQRLWRAVRTFEQLHPAF
VSLTYGAGGSTRDRTVRIAGQIATETTLLPVAHLTAVDHSISELRGLVGSYADRGIVNLL
ALRGDPPGDPLGDWVMHPEGVEYAEELVRLIRELGDFHVGVASFPEGHYRAKDLDHDTYY
LLNKLRAGADYSITQMFFEVEDYLRLRDRVVAADPVQGEKPIIPGLLPITSLKQVRKIVE
LSGSQIPPYLEERLARAAGSGPEEDRAEVRKVGIELATKMSERLIAEGAPCLHFCTLNFS
RATQEVLTNLGLAPVPA
>A0A4P8KAB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus avium|TrEMBL
MSNTLSFEVFPPNTQVGTEKLLTTLEELQQLAPDFISVTCSNNRQTIEETTLRVADYIHT
ELQVPTIAHLPAAYLDQAQVQRLVAQLDQIGIHQILALRGDIIPELPPKKDFTYASDLID
YVKQQAPHFHISGACYPETHPESQNRIEDVKNLRRKVAGGCDQLITQLFFDNELFYQFQE
SCDLADIKVPILAGIMPIVNRKQALRLIKTTNTKLPRKFLAILEKYEHDPIALKEAGLAY
AIDQIIDLATQDVAGIHLYTMNNAEVAKHIYYNTKNVLKGQIEVR
>A0A2N5BUD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FFUP_PS_41|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITGMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLQLPR
>F4LTH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidanaerobacter acetatoxydans (strain DSM 21804 / JCM 16047 / Re1)|TrEMBL
MSLLQKALESGEFAVTAELAPPKGTDFSHALQNAELFGDRVHAINVTDFQSSSLKATSLA
MCKALIDLGLEPVFQITGRDRNRIAIQGEMLSAGFFGVKNLLALTGDHTTVGDNPGAKPV
YDLDSIGILQAATMLASGVDMGGNKLEGSPSFFLGASVTPEYDPIELQLIKMKKKIIAGA
KFFQTQAVYDIRTMEKFKEITKHLNTKILVGIIPLKSAGMARFMNKKIPGINVPDELIDR
LKLSKDPVQEGIKIAGEFIVELKNRNLCDGVHIMAIGAEENVPLILDAAEL
>T0PJF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas salmonicida subsp. pectinolytica 34mel|TrEMBL
MGFHSARQVEALNQSLADLSGDIGVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKDPA
>A0A023BY54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimarina atlantica|TrEMBL
MKVTDHIKKAKEKTLFSFELIPPQKGRSIQELYDNIDPLMEFNPPFIDVTTSREEFIYID
REGLLDKKLTRMRPGTVGICASITHKYNVDTIPHVLCGGFTKEETEYLLVDCHYLGIENV
MALRGDAMKEEKYFTPTKGGHSYANELVEQILNMNKGKFLHEVVETDNKSDFCIGVAGYP
EKHMEAPSVDSDIRRLKDKVDAGADYVVTQMFFDNKRYFDFVKKAREAGINVPIIPGIKP
VAVKRHLQLLPQVFKLDMPDELVRAVEKCKTNKEVREVGIEFAIQQSKELMEFGVPVLHY
YSMGKSDNIRKIAEGVF
>A0A533ZUD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MADGPPRLKEALDRGVFAVTVEYNPPKGTNLDKLLASARSLLGRVHAVNVTDNTAAVMRA
GSLSVCRLLYEMGHDPVMQITCRDRNRLGIQSDLLGAHLLGIRNILCLTGDYPTVGDHKD
AKPVYDLDSVQIMQLVQGLNNGRDLAGNKLDGSTDFVIGAAVTPEADPVGPMLVKFETKV
NAGAQFFQTQAIFHPDLFNSFMRAVRKFKVRVLAGILLLRSAKMAEFLNANIPGVAVPEE
MIAELRAAGDKHALDVGVEIAVRTIKAVRPHCDGVHIMAIKAIDRLPEILTKAELG
>A0A532UMF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium (candidate division B38) B3_B38|TrEMBL
MNANSGLKKLLAKEEFVVIAGIGIPRGADFKPLEERYKLLEKKVNAFYIPDNPGANVHLL
GLAAAVHLEKLGGETVLELNCRDRNRIAIQSSILGAAALGIPNLLFSTGDHQTLGNFRGA
KRVYDVDLTQAIQVARGMRDEKKFSNGEEVAQPPSIFIGAEANPFADPFEFRAALMAKKV
EAGADFVQIRAVFDLERFGKWIKLVRQQEPLQKIPILAGIIPLVSVEQAKSLQEAPGMIV
PDSIIQRLEASGKPEDEGIKIAKEIIAQVKKTEGVRGIVLHASGMESLVPDLIK
>A0A3L7AFQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycetocola lacteus|TrEMBL
MPGASTEPGIRPTDIFPKEIGVATTFSFELYPPRSAAAADALEVSLAHLVASGPEFISVT
YGAGGTTTDRSLRVLQQLRAGGVDAMAHLTCVGSSYAEASAMIHEFLDAGITKFLALRGD
PPAGAKEGEDFLGDLGSAGELVQLIHRIRAEKAQFVQPPLAGFPRGTRLAPQPKVTIAVA
AFPNGHPRSRSVSQDLDTLLAKEAAGANLAITQLFFDPEDYLRFVDQARAAGITMRILPG
IMPVLSAERLHRIVQLTGEKLPTELLRKLEAAGSPEAQFEVGVDHASSLSRALLNGGASG
LHLYTFNQHPAVLRILRETGLYVPVKEYA
>A0A1E7GRP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium S5133MH15|TrEMBL
MNPFADPYEIRVPRLKLKMEAGADFVQTQCIYNMDKFKTYLGDAKREGLTEKIKILAGVT
PLKSAGMAKFMRRMVAGMDIPDEVVKRIADEPKEKQAAKGIEMCIEQIQELKEMEGIAGI
HVMAIEWEEKLEEIIGGAGLLPRPIIE
>A0A318Y235|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminiclostridium sufflavum DSM 19573|TrEMBL
MIKNIYRGKKTVFSLEVFPPKKEEDFPLIFNALDELKGLKLDFISITYGAGGSTSRRTLD
IASYVQNTCGIEALAHLTCVSLDEPAFNKYLGKLKENQINNVLALRGDRPKDMSDEAYGS
RPYKYAIDLVNNIKQKSDICIGGACYPEVHPESRNQEEDLYFLKSKIEAGADFLLTQLFF
DNTRFYRFYEQLVNYGISVPVSAGIMPVTSSGQIRTIVDLSGASIPAELKTIFDKYQNKP
EDFKKAGIEFAAKQISSLLSFGVKGIHLYTLNKADVSTAIFENLGLK
>A0A2N6P8Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. dentisani|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A2A3T9Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MTVRYEANPPKILPDVNTDESIAKFIDRIKRISKKCDAIHLTENVLGFQRVSPIKVGEII
KKEIPNLPITVSLRVRDKSEKEITEFVENCITIGFSGILILMGDPSQTGKADLGQIPSXT
VKRLREQGVDSKIDLYLSMSNKPNFSKISKKLEAKPKGFMTQVVQNIDQVQNLADNLKGY
LIIPIILFPSDKNEKSAKFLNMDLTEYSKNFDEFVNKVHKITGDILLTSPSDFTGLNNFL
EKPIN
>A0A6I5MY36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium choloepi|TrEMBL
MTAPLFSLEVFPPRRNASIGTIYDTLDGLQGLSPAFISVTYGTGRKTDKTATARIANTIR
TEYGIDAVAHLTAVYLSKADVDEALGLFDEAKVSGVLALRGDRDTERPPVGDFRHATDLV
AYIRERRPDLKIYGACYPEKHPEVETMAEDVRHLREKVDAGCSHLVSQLFYDNDDFYRFL
EMTDAAGIDVPIEAGVMPVMNPKSVVNMSTKCGSSLPPAVRRMLERWGDDRESLRAAGVC
YASEQIADLVANGVDGVHLYTMNHPSVTRRIWSNVRPLFS
>A0A6H1A0D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. JQ2195|TrEMBL
MDHQTPRSIGQLIRSGERSFSFEFFPPKDAAGEEQLWQAIRELEPYQPTFVSVTYGAGGT
TRDTTVAITGRIAKETSLLPVAHLTCVGHTVDEVRDVLGSLAASGVHNVLALRGDPPGGP
GTPWEPTNGGVNYASELVRVIKDAADVSVGVAAFPEGHVDAASLDDDVAVLKAKQDAGAE
FAITEMVLRASDYFALVERAAAAGVDIPIIPGVMPILNINSMRRMVELSRRELPTEVVQR
LYPFEDDKAGLRAEGIAIATELCDAMLDGGAPGLHFYTLNRSKATREIFEALRITV
>A0A2G4J1P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MTIRYEANPPKILLDVDTDESIKRFIEKIKIISKKCDAIHLTENVLGHQRVSPIKIGEII
KKEIPNIPITVSLRVRDKNEEEIEKFVDKCISIGITGILIIMGDPSQLKDVKSGLIPSDV
VSNLKKKKYDSKIELYLSISNKPNFLKIEKKIKAEPKGFMTQVIQNIQQVQTLADNLKQF
SIIPIILFPSEKNQKSADFLGLNLEEYNKNFDKLVKEAYRITGDVLITSPNDFNGLKEYL
EKHW
>A0A1C3WSF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium multihospitium|TrEMBL
MSHIDENPLGVHLPLDPLPGHYSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLNEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRTDALVAERLHQISEGREENQQAMAEIAA
HHTPQQAH
>K6X4G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia rhizosphera NBRC 16068|TrEMBL
MIDKIRRRETGAVLYGMVPPKITTPHSELAEIAQRQRTRISSLPVDGLVVYDLQDETDRI
DSERPYPFIETLDGFEYSRTYLAELDLERVIYRAVGKYAPSELESFLHDADPSRELTVFV
GAAAQGQDVALTLDEAYRLRAEIPDAPMLGGVVIPERHRAKGTEHLRVIGKIERGCEFFI
SQGVYDRQAAKDFLSDYYYEALRRDVDLVPILFTLTPCGSSKRLEFMKWLGISIPRWLEN
ELRHSDDILEQSVAVCEQTYDELRTFADAKGIPIGVNVESVVVRTVEVEASIELLRRLVQ
T
>B8ETT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2)|TrEMBL
MSEHPSCELPRASRTHCPDIRVSFEFFPPKTVAMEALLWESINRLAPLGPSFMSVTYGAG
GSTRERTHQTVARLAKEAVVRPAAHLTCVGASMKEIDGIVQGYWDAGVRHIVALRGDPPD
GLGATFEPHPQGYKNSCALVAGIKRIGDFEISVSAYPERHPESLSLDADIDFLRAKVDAG
ASRAITQFFFENEIYLRYLDRLRAAGVDIPIVPGIMPMQNFKQTAGFAKKAGASVPQWLA
DRFEGLDDDPQTRRLVAATVAAEQVLDLVDHGVRDFHFYTNNRADLVYAICHLLGLRPKP
EQKEAA
>A0A0R2P6W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium BACL2 MAG-121001-bin67|TrEMBL
MNSAPTFSVEFFPPKDQAGEERLWSALKALEVYKPDFVSVTYGAGGSTRDRTIRITSEIT
ARSGLSTIAHLTCVGSSRDELIEILSQYKVSGIKSILALRGDPKGGPGVKWESTAGGFDY
ADQLVLLASSMGFEVGVAAFPDGHPASKGNFEQDIKVLLEKERCGASFATTQFFFDVKGY
INLVNQIRAKGSKLDIYPGILPITNFAQLKKMSELAGSAIPIEIQRRVEAAGDSPEEVVK
VGIDIASELSKDLLDYGVPGLHFYTMNSAAPTIEIIRRIGLR
>A0A3G8ZVW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nakamurella antarctica|TrEMBL
METVIDRLSAGGAQFSVEFFPPKDDAGEIQLWRTIRELEPLRPAFVSVTYGAGGSSRDRT
IRITGRIATETTLVPIAHLTAVNHTVAELRHVIGSYASVGVRNILALRGDMPGDVTAKYQ
AAEGGLKYASDLVRLAKSLGDFTVGVAAFPEMHPESVDQESDMRYLVEKLNAGADFATTQ
MLFSATDYLRLRDRLRAAGVNKPLVPGIMPIASWKGIARQALMAGQQVPQAVIDRFSPIA
DDPEATRAEGVQFAIEMCRQLLAEGVPTLHFYTMNKSRATLEILEALGITRARSFAAATP
>A0A7W6JAL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gellertiella hungarica|TrEMBL
MAKIPASIEVAPKQAIESADLPGLFPAGSRVYITDIGTDPTDVLVQAAVRVAKLGYKPVP
HFASRRLTTKAALEERIKRTVGEAGVTDVLVIGGGLEKPAGEFGSTMEVLETGFFEGNGI
TYIGVAGHPEGSPDFSDAAAVEALKQKQAWAAKTGVNVRVVTQFGFDAKKFITWAEGLKA
HGIDLPVHLGVSGPAKITTLIKFAAMCGVGNSISFLKKNALSVTAMALGHNPEEIVSPIE
KHFQANPAGPIQQIHIFPFGGLKKSSEWLVDRGSWSKNSVQSSAMAASH
>A0A809K055|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium adolescentis|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVDEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREKRPNLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYNNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCESRVPEKLAVLLDKWGSDTALLKEAGIAY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A1G2ZY06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RBG_16_55_9|TrEMBL
MPKKKLSNSLTAGSDFVVVAELAAGPGGNFGPIQKFLSAADKTGLDSLPKGFNFVGITVP
QNPGGAANIEPSDALSRIIAANLLSDLDFIPHVSCKDHNVDAITSSLIHYRQRQISSVLA
LTGDKPVMARGVFEIESVGLLQLIERMNCESYLKAKPEQWDGVAQFFPGAAVSPFKYTEG
SQMQQYYKMEKKVACGARFLITQVGWDWKKSSELMRYLDENGIDIPVLGNVYLLSTATPA
PRLMHEGKLPGCFVSDEFYAHLQSEKVEQHVERAAQQVAMYKELGAAGVDVGGLPDFATF
AQILNRASQIGADWEKYKDNLCWPGGEGFYLYEGAGQQAVTTRMKKKFRQKTFDFMHRAI
LDPDHTGFKLFRGSMALLGTKKGKGFFYKSFFAAERSFKYLMFDCEDCGDCYLPENFSYC
TIGGCEKGMSNAPCGDSTVEGLCGNNLERTCIGDLIYRAAAAKTCGRNLLRNTLNKPRMH
ALENTSSILNYLFAKDHTKPSPLISIGEMLDASNPAVGSAMKQCGDALDQTKSLNGAFGY
LRSLIQTQVDEGASYIAINVDALANGDEQEAARLIQSYVRLVRRLGKGVPACIDSRYEKA
LIAGLKGWYDTKNQVEPPVIGPVSVSSPDTILSLRRQYDFGIVGTLTDNHTEAQHNPHSI
EESFDLAKRLFNRAVSEYHFKPDQVFLDPVTVPLMSDEPESEGMAGQTYKAFRIIQRIKH
DSAMKKSHCLLKINRATDRIAGRKVGVARAYVARAMEYGMDAAFVDVTRHYGQEPADQAL
LDLIDAYAEMDGSAQKVETAKALMTKLCGGGKKPLQKA
>A0A7W8P218|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia youngii|TrEMBL
MTSLTMNPIELSFEFFPPKTQEGIDKLRATRAQLVSLKPKFVSVTFGAGGSTQQGTLDTV
IDMTKEGLEAAPHLSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGAVGELRYAS
ELVSFIRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAY
FRFVDDARQLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRA
FGLDVVTDLCQRLVDAKVPGLHFYTLNAATSTKAICERLAV
>A0A7H4ZF85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia enterocolitica subsp. palearctica serotype O:3 (strain YE-P4)|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A1V4MGG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|delta proteobacterium MLS_D|TrEMBL
MKISDILASDRFSLSFEVFPPKRDGNIDNLYKTIEELETAHPDFISVTYGAGGGTRDTTV
EIASKIKNVLGVETLAHLTCVQATSADIADILEEFKRNNLENILALRGDPPGDAEMFVKT
AGGFGFANELVNFIRSQGDFCIGVAGYPEVHIEAPSAEADLENLKRKVDAGGEFIITQVF
FENDAFYRFRDRALKAGINVPVIPGIFPIFNTKQIPKITELSNSKIPSSLLDKLEKASDR
PEEAEKYGVEFAVRQGADLVRNDAVGLHFCSMNRSSHVLKILSELELPRRRPARQQNG
>A0A2P5N4N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas sp|TrEMBL
MNISFEIVPRSLDAFDQQYAFAESLGTDITVINVPDIQHFDTRSWQLASRVDRSRYRFIP
HFRAIDFKIESGELFRIIETHQLDSVLLVSGDPPEGLKRAYYNTDVVDLIRAVRQRFPSL
HIYAGFDPHRSGIQDECDYIQRKADAGAQGFFSQPFYDSRMIEIYSEQMNGLETYVGISP
ITTQASMNYWEVKNKVKFPKGFSPDYDWNVAFANHVIQTAMQQGLNVYFMPIRIDLERYF
KALHTFAG
>A0A1M6LFF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatibacillum alkenivorans DSM 16219|TrEMBL
MKLKEALDKKLFVVTSEVQAPFDENPQELLNNLKQIRGRVDGVSIAESDIQGIVGDTVKT
CEILNENRFDAIYQTTTRDKNRIQLQKDLLTAHDAGVENLLVFTEDYRITGDSLQEMMFF
HVDAGKLDSVLKSMRQGHSVEGKPLDKQADFLLGSGVESGWGRNVPELELKEMEQMTGVG
AGYFLTTPVFDLDLFEKFLKQAKTFGVPVIAELMILRTAGMARFLNRHIRSGLVPDWVIK
KLAQAPDKQKASIELFADLAKGLKDLCDGVHIISIGGTDKLKHYLDAAKLR
>B7UDD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium ammoniagenes|TrEMBL
MVPRISASAPLDYLELDPAGHPRVENKEQAFSRTALSFEVIPPRHDADQAKIANLLQVLG
SYNPDYIAVTSSKRSGWLEGTAKFIEQISSTTTMRPLAHLACTAGDKRELISWINVLVDA
GVRGFLALRGDLEPGQTSLPEGYLQHGDELVRLIRQLEGEQAARFAAGRLAVAVACYPNG
HAESANDDEDFDVLLSKQRSGADLAITQLFFDAEDYLKFSQRAQLAGTKMPLIPGIMPIT
SLKRAQRMGELSGLEVPPKLIDKLSRARSPDEEYAIGMAHTVELAQAVIAAGAGCLHIYT
HNNADITQELLAEIGISASIKN
>A0A178GH87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. SFD|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKLVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A1M6CNW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatibacillum alkenivorans DSM 16219|TrEMBL
MRVSKLYQDSQKPVVSFEFFPPRDEKAGQAFDKTIDALKPLNPDFMTMTFGAGGSTKDGS
YQAVKNLMGRDIATVAYLAGFGLSPDYITQVLDRYKELGVETIFTIRGDEPREKDFQPHP
DSFPYACDLIEFIASKYDFDLGCAGYPEGHIDAESLDKDIEYLKRKVDNGAKYVVCQYCY
DENVFFAYVDKCRAAGIQVPIIPGIMPVYTVKLTRMLARICGTTIVDGMAANLEKLEGAD
AQAVFDYGVEFALDQCRGLLKKGVPGLHIYTMNRAPSTTRIITALREENLL
>A0A1E7Y059|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium adolescentis|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVDEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREKRPDLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGISHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCESRVPEKLAVLLDKWGSDTALLKEAGIAY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A891HD31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. LZH-2|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETNLVAAPHLTLVDASDEELLDLAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPSWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPKAV
>A0A7K2PKE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5470|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPMADWVAHPQGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDSDVTRFVD
KCRAGADYAITQMFFQPESYLRLRDRVHAAGCATPVIPEVMPVTSVRMLERLPQLSNASI
PSVLKERILTAKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHRPQA
>A0A7Y8KU14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. SAM-B|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAAKLKVFAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFDAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASELISFI
RAEHGDAFRIEVGAYPETHPQANDALLDLKHFKTKIDAGADAAITQYFFNADAYFHFVDA
VRKLGVTVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAESVRAFGAEVV
ASLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLRS
>A0A6A7LG18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrososphaeraceae archaeon|TrEMBL
MKKIRFELNPPKTVQNRYFDEHELRRSLSSLIKRASQLVGLVDGIHITDSVLGVPRVSGI
SLAHLIRRDGNRLPISCSVRARDRNYTSFMQFVGDAILLGLESILILKGDELGPDSSTSN
LKPTEILRVLRSEKYDRYIHFSLAVPSKANDKFQIEKKILSGPHSLVTQSIESLADLREL
ADLATKHGIKTVACIMIPSEKNLKSAQMIGLDWHEYSNDPVSFILEANKIADEVLLTSPN
HFAAAIEVLKEISNQT
>A0A730WHI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. houtenae serovar 1,40:z4,z32:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8J5TZG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. rapae|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFEATLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLIARLDAVKGDDERVKMVGVDIVSELIEKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKARLTSPELQDSVCFYASNARGDYLSSDNSDHVNGSAEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVMIIGWSM
>A0A0F2N9U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium BRH_c16a|TrEMBL
MKTKSKLEKIFKNGHMAVTSECGPPRSSDPEHIIKKGHIIKNHVDAINITDNQTSVTRLC
SLAACIHLKLEGMEPVLQMVVRDRNRIALQSDILGAASFGINNMLCLTGDHQSFGDHPKA
QNVFDLDSMQLIQTVRHMRDEGKFLGGEEIKVPPNLFVGAAANPFADPFKIRVPRLAKKI
AAGAEFIQTQCVYNLEKFELWMKGVVERGLHEKVYIMPGITPMRSVGMAKYMARAVPGMD
VPDELIKRLSGVPKDKQAEEGITIAVEAIQRLKEVKGVSGFHIMAIEWEEKVPEIVERAG
LYPRPKVD
>A0A4R6Q7T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium dankookense|TrEMBL
MKVTQHIENADGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPSGLLQKKIVKKRPGTVGICAGIQNKYEVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKNETYFKPEKEGNEYATDLVLQINNLNKGIYLDEDLKNSAETNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNKKYFDYVAKCRAAGITVPIIPGLK
PLATKKQLNLIPHRFSLEIPDDLIMEVVKAKDNDAVKQIGIEWCIAQSKELVAAGIPVLH
YYSMGKAENIKAIAKEVF
>A0A2E5MX24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetovibrio sp|TrEMBL
MNTQHTEKANIGWSIEITPKQGLKIENFAKHLPINTTVNVTCLPGTSPNDTIQTAEKLKN
SGMNPVPHIAARSLADLEELDYLLQKLVKKASVSEVLVIGGGGKKQLGQFSDSLSVLKSG
LLQKHGITKIGVAGHPEGSADISEEQLKTALLEKNELAKVEGLNMYVETQFCFDHEVILK
WESLIRDEGNKLPIHVGIPGPATIKELFRFARLSGIGNSMSFLTKQARNVTKLLTIQSPD
DLLLGLTKGIENDRGCLIDNFHFYPFGGFVETATYVQSFFSKYNSSNFYEQDKNNKLVS
>A0A2M7JCJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desantisbacteria bacterium CG_4_8_14_3_um_filter_40_12|TrEMBL
MSKQFKDVLASGEFVITSEIGPPKGTNIEKMLHHIEILKDKVHGMNVTDNQSSVMRLSSV
AVCHIITDHGGEPILQMTCRDRNRMALQSDLLSAYVLGVRNVLCLTGDHISLGDHKGAKQ
VFDLDSVQLIAAVKSLEAGQDIGGNKLDGGVEFCVGATATPEADNMDSQFLKFRKKIKTG
AGFFQTQAVYDMVKLKAFMEYARQSDVKILAGILVLVSAGMARYLNANVAGVTVPQELID
EMAGAEKGKALQKGMEIAARQIKQIKDEKICDGVHIMAIGKEEVVPEILSMSGV
>H1YAC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter paludis DSM 18603|TrEMBL
MKITEHIANANGKTLFSFELLPPIKGQSIQGIYNAIDPLMELKPPFIDVTSLREDHVYKE
HENGLLEKLITRKRPGTVAVCAAIMNKYKVDAVPHLICGGFTKEETEYALIDLQFLGIDN
VLVLRGDARKAEPGFVPTPGGHAYATDLLQQVMNMNNGMYLLDTGPTSYKTDFCVGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGANFIVTQMFFDNQKYIEFVNNCRANGITVPIIPGLK
PITVSKQLISLSKIFHIDIPEALSEAITDCKSEKDVKEVGIQWMIQQCKELVEFGVPVLH
FYTMGNPEPTKRIAQAVF
>A0A286ETS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jatrophihabitans sp. GAS493|TrEMBL
MVRTVREALSSSGPTISFEFLPPKTADDERVLWNTIRNLESLKPSFVSVTYGAGGSSRDR
TIEITERIASDTTLLPVAHLTAVDHSVAQLREIVGRFADAGISNLLALRGDPPGADPMGD
WIAHPEGLSYGHELVTLLRGLGDFCVGVAAFPFKHPRSTSVEEDTRRFVEKCRAGADYAI
TQMFFDGDDYLRLRDRVVAAGCDIPIIAGVMPVTAIGTIARSEQLSGAPFPKALAEKFQR
VADDKKAVRELGIAETSLMVQRLLDEGVPGIHFITFNRSTATREVWSNLGLSVPAG
>A0A0J5XNQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium peruviense|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWQSGIRHIVALRGD
LPTEGGKPEMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTSVFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A6A2YBY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hibiscus syriacus|TrEMBL
MKVIEKIQSLQQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDAIGDNGLATPEAYQNDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMTGFCKT
KIPDEVTTALEPIKDNDEAVKAYGIHLGTEMCRKILANGIKMLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPQGRWGDSQN
ASYGALSDHQFMRPRARDKKLQEEWSTPLKSIDDIQEKFKSYCLGKLRSSPWSELDGLQP
ETKIINEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSREKL
DALVKKSKSFSSLTYVAVNKDGDLVSNIGLTSVNAVTWGVFPAKEIIQPTVVDPASFMVW
KDEAFEIWARSWSALYPDGDPSKKLLEQIQRSYYLVSLVDNNYMDGNIFGVFEDV
>A0A009NBY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 1475718|TrEMBL
MTLADRVHSDHDIAPLEASKSYPDIIDKVLHFSGKARDIQDFELFLEQAKSANIQNLLLL
TGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLH
KKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQQILACVMPLTLGRANYMVKHKVAGI
VITPHMLKVLAEEKQAGHTDRVYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIE
QYRHLNLKALEELWSSLWQVKTGKEFIPEITRFSRQPTSKQLIKYRQLHVMHEAMFGSKI
AKGVGRFIFKASFWENSLVAKVLIKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGL
ANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQTEILKEKLIPTVPLETRGTSSWKNWY
LATEA
>A0A8B7PIG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyalella azteca|TrEMBL
MVQGNIAEVDHTVHSSSPSLAMSSSPADPLAHLKAFINERNTLHSHGETENELPATPHHQ
LDYLTGYQNLREKISARIESRDKFFSLEFFPPRTKGGAVNLLARFDRLKEGDPLFCDVTW
HPAGNPGGDTETSSLTIAGAALNYCGLETMLHMTCCYMTKAEITRHLSRAKDLGLRNILA
LRGDPPHGADNWSPPSDGFTYGSDLVEYIHAQFGDYFVVGVAGYPTGHPDATSYEDDIRH
LKEKVDKGADFIITQLFFKAETFIKFEKDCRAAGITCPIIPGIMPIQSYDSLRHIVKLSR
LDVPKEIMEVVAPLKDNDEAIRNFGIHHASTLIKELFDKGIAPGVHFYTLNREVATTAIL
KKLGLWAGAPRRPLPWKMAANYKRCCEDVRPIFWATRPKAYVYRTQHWDDFPNGRWGSSE
SPAFGELKDYYLFYLKSKSSRDELLSMWGESISSEEDVWRVFHAYITGTPAWEGAKVVTK
VPWNDDELSAETCQLRDKLAHFNLRGVLSINSQPNVNGASSTDPVVGWGMPGGYVYQKAY
LEFFTSRENAAALKQVLPLFPRVNYHILNRDGSEDTTNCHRHRPLAVTWGVFPGTEIIQP
TVVDSVSFKAWKDEAFTLWEVQWGKLYDEKSESRAVISHIANNYCLVNLVDNNYPEQSCL
WDVLEAMFTWKELDAKKDSNDDSCSVARGSSCSSEEVLVKRMSKAQIVPMIESPDCANDM
QVPCTNELR
>A0A2X4R2V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemella morbillorum|TrEMBL
MRNLLERLEKDVLVADGAMGTALYGNGLESCHEYNNISNPDSVEKIHRAYIEAGADIIQT
NTYAAKKCQLKTYGYEDKFEEINIRAAEIARKAAGQDTIVFGTIGAIRGLRECELTLETI
VKETLDQVKVLLSTDKIDALLFETYYDQEEIRAVLTEARKLTNLPIITNISLLEAGITQN
GEKVTDALSTLVNLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSAYPNASLLQLTQTT
HGNEYRFRKNSAYFEQSAKLLVEEGVRLIGGCCGTTPEHIRAIKRGIKNLKPIRRKIITP
LPAEEELIRVANNNPTIVDKAKKQVTIIAELDPPKHLNIDTFIEGAKAIDKKNIEAITLA
DNSLASTRICNLATAALLKEHITTPTLLHLTCRDHNLIGLQSRLMGFDLLGINNILAITG
DPSKLGDFPGATSVYDVTSLKLIPFIKQLNDGLGYNGASLKKVTNFTVAAAYNPNVRDLS
KTKRLVEKKIKSGADYFITQPVFESDKIVQLAEFVADYPDTPFFLGIMPITSYNNAIFLH
NEVPGIKLSEDFLAKLEKVKDDKALCQKVALEESKKLLDVALKHFNGIYLITPFTKYDLT
IELIDYIEKNKTK
>B9XKW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedosphaera parvula (strain Ellin514)|TrEMBL
MSNFLNRLNQGVLLGDGAIGTLLYQRGQPLNASYDALNLQHPEIVSQLHRDYLDAGAHLI
ETNTFGANRIKLEKFGLAQKTVDINKHGAQLALEVACGRGAFVAGSVGPLSADPSSLSTQ
TKDSAYREQLEALVSEGVDALFLETFNRLDELAFVLRIARSLGNTPIIASLSFGDDGHTA
DGLRINEAFSRLKEAGADVVGLNCHFGPTIAEKLLEELIVRPGDLISIYPNAGRPYFYEG
RYIYHSTPSYFADFAPKLIAQGARLIGGCCGTTPETIAAMARVLPGLKPVESKQGLIVPP
SRISPSLKPAAPRTKSLLELSREKPIIVTELDPPKSLSLDKLLEGAQALKQAGTDFVTLA
DNSLAILRVSNMAAGFLVKEKTGAEPLIHLACRDKNLIGLQSELMGLHALGIDHVLALTG
DPAKVGDHQEATSVYDVNSVGLIRMIKRLNEGFAANGRDLKTKTQFVIGCAFNPNARNLD
SQVRKLEDKLEAGAQFVMTQPIFDPVLAKVTHEKTKGLGVPVLVGVMPLLNSRNAEFLHN
EVPGIIIPEMTRDRLRGKEGAQANAEGLAISRELCDAVLDCFNGIYLITPLMRYDLTVEL
SRYVREHVRRPKVPLRHFDNISVD
>A0A6I6BL27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemella morbillorum|TrEMBL
MRNLLERLEKDVLVADGAMGTALYGNGLESCHEYNNISNPDSVEKIHRAYIEAGADIIQT
NTYAAKKCQLKTYGYEDKFEEINIKAAEIARKAAGENTIVFGTIGAIRGLRECELTLETI
VKETLDQVKVLLSTDKIDALLFETYYDQEEIRTVLTEARKLTNLPIITNISLLEAGITQN
GEKVTDALSTLVNLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSAYPNASLLQLTQTT
HGNEYRFRKNSAYFEQSAKLLVEEGVRLIGGCCGTTPEHIRAIKRGIKNLKPIRRKIITP
LPAEEELIRVANNNPTIVDKAKKQVTIIAELDPPKHLNIDKFIEGAKAIDKKNIEAITLA
DNSLASTRICNLATAALLKEHITTPTLLHLTCRDHNLIGLQSRLMGFDLLGINNILAITG
DPSKLGDFPGATSVYDVTSLKLIPFIKQLNDGLGYNGASLKKATNFTVAAAYNPNVRDLS
KTKRLVEKKIKSGADYFITQPVFESDKIVQLAEFVADYPDTPFFLGIMPITSYNNAIFLH
NEVPGIKLSEDFLAKLEKVKDDKVLCQKVALEESKKLLDVALKHFNGIYLITPFTKYDLT
IELIDYIEKNKTK
>A0A377JEJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parainfluenzae|TrEMBL
MSYAKEINTLNQHLADINKKINVSFEFFPPKNEKMESMLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGIEAAPHLTGIDATPEELKEIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIEAEIVPGILPVTNFKQLQKMASFTNVKIPAWLAKAYEGL
DDDPTTRNLVAASVAMDMVKILSHEGVNDFHFYTLNRSELTYAICHTLGIRPKTNP
>A1WFN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verminephrobacter eiseniae (strain EF01-2)|TrEMBL
MIAASAQGTGFPVSFEFFPPKTPEGAGKLRAARQQLYALHPDFCSVTYGAGGSTQQGSFD
TVRDILAEGMAAAAHFSCMGATGPSVREQLATLKAMGVKRLVALRGDLPSGYGAGGQFQY
ASELVAFIRAETGRDFHIEVAAYPETHPQARSPEADLNAYLRKVQAGADSAITQYFYNSD
AYFRFVEETRRLGADLPVVPGIMPISSSTQLLRFSDACGAEIPRWIRLRLQAFGDDSASI
KAFGLDVVTDLCDRLRSAGVPALHFYTLNQSTATLEICRRLGI
>A0A1F9ERC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_19FT_COMBO_46_12|TrEMBL
MKSGSRLEKVLEAGHFAFTGELGPPQGANVEAIRKKASFLKGITDAVNITDNQTAVVRMS
SWGASLVVLQEGLEPNYQMVCRDRNRIAMQSDILGAYAHGIRNMLCLSGDHQQFGNHPLT
KGVFDIDSIQLISMVKGMRDNKKFLNGDDIDEAPQIFIGAAANPFAEPFEFRVHRLAKKM
IAGADFIQTQCIYDMKRFREWMKQANDMGLTEKVKILAGVTPLKSGGMARYMAKNVSGII
IPDEIIERIVQAKKGAEEGIKICVEQIEELKEIKGVHGVHLMAIEWEHRVPEIAERAKLL
PRPQV
>A0A1L7CYJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sphenisci DSM 44792|TrEMBL
MSASTPSPVPGRQVPIRRALSLPGPGPVPFSVEFMPPRDDAAERRLFEAAEAFHDLGAAF
ASVTYGAGGGTRARTLRVAEDLAGRPLTTLVHLTLVDHTVAELRGILRGYLRRGLTNLLV
LRGDPPGDPLGQWRTTPGGLTYASELIDLIRAEEEFAGFEMGIASFPEGHYRAPDLEADT
RHTLAKLRGGAEYSITQMFFDVEDYLRLRDRLAAADPVHGAKPVIPGLMPITSLRSLRRQ
VSLSGSQLPAGLEERLLAAAAGDEEANRDEIRKVGIEVSTEMAERLIAEGVPGLHFMTLN
FTRATQEVLHNLGMAPAWGGGQSMQRDGF
>E3RM42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenophora teres f. teres (strain 0-1)|TrEMBL
MHISKKLAQAREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQTVYGLETCMHLTCTDMEKSKLDDALREAYQSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGGTF
IVTQMFYDVDLFLEWVGKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTRCNIPQHWTDAL
EPVKNDDVEVREVGKILVADMCRKLIAAGITHLHFYTMNLAQATRMVLEELDLLPDGEAP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNVKLWGTPMCIRDLSDLFVRYMEGKLDSLPWSEQAITTEAGPIRSDLID
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDFVDTWYLLNIVHNDFRETRGIFPIFDGLEVKDMDKPLYNPSVDL
PGVNGSEATNGTNVTNGEAEPHKKEAPGLIETAKAAAVEVTNGIKSLAVSN
>A0A3C1RRM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktothrix sp. UBA8407|TrEMBL
MNRFRTACQTLDEFIITAEVAPPKGADPSHMIEMVRLLKNRVHAVNITDGSRAVLAMSSL
ASSIILLHHGVEPIYQVACRDRNRIGLQADLLGAQALGIRNVLALTGDPVKAGDHPDAKA
VFDLESVRLLQAINKLNQGKDWNNKALPDGATDLFPGAAVDPQSSSWSGLKSRFERKIEA
GAQFFQSQLITDFERLDKFMTEIAGESKKPILAGIFLLKSAKNARF
>A0A3M0G5Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus antarcticus|TrEMBL
MSAEPTTTATIADLLATATEPLLSFEFFPPRTAEEEPRFSNAVDRLERFAPDFVSVTYGA
SGSTRERTIDASRELARRGDVTVGHLTCVAQSRRDTTEALEAYRASGITNILAIRGDMPG
GPAQRWEQHPEGLGTATELVEFIRDSGDFCVGVAAFPNVHQPDNDPELDARLVVEKARAG
AQYAITQLFFEASRWVELVDRVRSRGCDIPIIPGIMPLTVITQIERFAALADCELPADFV
AQLRAADNPAEVRRIGLERAETMCHELLEAGAPGLQFFTQNRWQATSEVISRLPLSRSRP
ARSCAASRG
>A0A520F9I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp|TrEMBL
MTFDSVRGRASEGWVTRTPSIVDRIRSSGDGRVPFSVEFSPPRDEAAEARLWRAVREFER
MGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWQKHPEGVEYAEELVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSV
RRMLELSGSSLPTQLEKRLATAAGDGPEENRAAVREIGIDLATEMSERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSGVADPAPVTPTPVS
>A0A7W0ZGU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAELLAHPRYEIIPLDGVDEQVLEHVPRDVKLTVTVSPTKGLDPTLDLAERLAAAGYEVV
PHLSARLVLDDGHLRWILGRLRDAEIGEVFVVAGDASQSAGQFEGAADLLRAIAESDHPL
SEIGITGYPESHAFISDETTIQAMFEKAEFATYIVSQICFDPPVTAAWIEAVWARGTRLP
IHVGLPGPVPRTKLLRISTRIGLGDSTRFLRNHGNWIGRALKRGGFDPDRLVAGLESALT
DTERKIAGFHIFTFNALADTERWRQQALARQRNGR
>A0A7K0LAZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKKIGEGVTYSFEFFPPKDPEGEERLWSAMGALEPIAPDFISVTYGAGGTTRDRTIRITS
EITQRTHIPTVAHLTCVGSTRDELIEILGRYKQAGIHNILALRGDPTGGPRAPWTPTPGG
LNHADELVTLAAEVGGFTIGVAAFPDGHPASGLDFAEDIEVLLRKEEAGASFATTQFFFE
ADKWKALVDRLAARGSKLPIIAGILPVSNVNQLNRMAELSGVPIPTSIADRFAALKESPE
DVKKLGVEIATQLCEDLLTAGVPGLHFYTMNTSSATREIFEQIKDKKRG
>A0A4P5R1S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSKLRDLLTQSKDVVYTAEFPVIDGGGMEQVKKNVDRLSPWFVAVNATDNTAAHAHASNV
SVAIAMKQHGLEPIMQIVCRDKNRLAVQADMAGANLHGIENIALLTGDDVTAGDEPETRR
VFDLDGPQAINVASILNAGTYLSGRKLSPAPNFFICSVENPFAPPHDYRIERALKKHRAG
AQMIQLQIGYHPDRLEKFCAGVAATVPDLAIIPSVVLIKSAKPLGFMNDKVPGISVPQEV
IDRVAQSADQAEAAYQLALEQAKHALSLPGVRGLHITDFRHDDTLERLMYDLGRTPNQYK
>A0A7K1A1M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTIGLGRSLADLIAAGQRSFSFEFFPPRDEAGEEQLWRAVRALEPYRPTFVSVTYGAGGS
SRGTTVRVTGRIARETSLLPMAHLTCVGHTREELESILDEYAAAGVRHVMALRGDPSDGP
RAEWTPTEGGFTYASELVELAAARGDFRIGVAAFPERHPSSPSLDHDADVLVAKAAAGAE
FAVTQMFFRASDYFDLVERVRERGADLPILPGIMPILNLDGIRRQGELIGTDVPEEIVAR
ISAHQGDPARMRAEGIAIAAELCEELLAGGAPGLHFYTLNFSRATLEIFEKLNVTV
>G5JL17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus simiae CCM 7213 = CCUG 51256|TrEMBL
MSQFLTQLKDNILVADGAMGTILYSEGIDTCPEAYNLSHPDKIEHIHRSYIAAGADVIQT
NTYGANFEKLKNFGLEHKVKEIHQAAVRIAKKAATDHTFILGTVGGFRGIKQDDLSLQTI
LYHSEIQIDTLVEEGVDALLFETYYDLEELTHVIKHTRQKYEIPIIAQLTASNTNYLVNG
TDINSALKSIVDCGANIVGLNCHHGPHHMQESFTHIELPDQAFLSCYPNASLLDIENSEI
KYSDNAQYFGTVAQQLVNEGVRLIGGCCGTTPEHIKFIKSSVANLKPINSKKVVPITTSI
HFNQSSTHTKQNLTSKVRERPTVIVELDTPKHLDTTKFFDNIAKLDKANIDAVTLADNSL
ATVRVSNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKCTHFNIAGAFNPNVRKLDGAVK
RLEKKVDSGMSYFITQPVYSKEKIIEIYHATKHLDTPFFIGIMPIASYKNALFLHNEVPG
IKMSDDILAQFEAVKDDKAKTRQLSLTLSKALIDTVHQYFNGLYIITPFQNVEDSLELAA
YSKSITTHKEAIL
>A0A6L6EGC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSEHMPSRLGGVRVDDSPKPTTHLGVVAAALAAGQPCISFELFPPKTDEGEKNLWAAVHE
LEAINPTFVSVTFGAGGSTRDRTVTITQGIAEDTELTPVGHLTCVGASADELRSVVEQYR
RAGVSTVLALRGDPPGGLEGPWVKHPGGFEHAVELVELLASYGDMSIGVGAFPDGHPESV
SLQQDAEVLAAKQAAGAQFAITQFFFNADHYFESVALAQSAGCTMPIIPGIMPLTNYTQV
QRFAELSGVEVPGELTRRAQAIADDPEAVRALGIAEATHLCQQLLAGGAPGLHFYTLNRS
SATREIYANLGLS
>A0A7K0MX91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
LQGSEFPKDLAAKLEAAEPDGTEAVHRVGVEEATRRCRELLDGGAPGLHFFTLNRSMATR
EIYEALGL
>A0A7K0T0V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTSLSTAQRYPDAVEMRSVKSGLTYSFEFFPPKDVEGEERLWAAMSQLESIAPDFISVTY
GAGGSTRDRTIRITSEITARTHIPTVAHLTCVGSTRQELIEILGKYRSAGIKSILALRGD
PTGGPRSPWSATPGGLNHADELVTLAAEFGGFTIGVAAFPDGHPASDGDIDKDVQVLLEK
EKRGATFATTQFFFDAGKWKTLVDKLEAQGSTLPIIPGILPVTNVKQLNRMAELSGVPIP
SHISECFAKVEDNPEDVRKLGVEIATKLCEDLLEAGAPGLHFYTMNTSSATREIYSQIKD
ER
>A0A844Y1S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania gaetbuli|TrEMBL
MREAQRALEAPLFSGLPGDIDVSFEFFPPKTEAMAQTLWHSVETLAPLRPRFVSVTYGAG
GSTRERTHAAVRRIVNETAMPAAAHLTCVNATREEVDAVAREYWEEGVRHIVALRGDPPE
GGSAYTPHPGGYANAAELIAGLKKVADFEISVAAYPEVHPDSPDRQADLDNLKRKFDVGA
TRAITQFFFDPQCFFEFRDRATAAGIEGEIVPGIMPVLSFAAVQRMSGLCGTAIPHWMEG
LFDGLDDRPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKA
>A0A7K0Z0I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTSLSTAQRYPDAVEMRSVKSGLTYSFEFFPPKDVEGEERLWAAMSALESIAPDFISVTY
GAGGSTRDRTIRITSEITARTHIPTVAHLTCVGSTRQELIEILGKYRSAGIKSILALRGD
PTGGPRSPWSATPGGLNHADELVTLAAEFGGFTIGVAAFPDGHPASDGDIDKDVQVLLEK
EKRGATFATTQFFFDAGKWKTLVDKLEAQGSTLPIIPGILPVTNVKQLNRMAELSGVPIP
SHISECFAKVEDNPEDVRKLGVEIATKLCEDLLEAGAPGLHFYTMNTSSATREIYSQIKD
ER
>A0A7K1DRN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARIADLLAAGRTFSFEFSPPKSAAASMSLGRTIAELEPLGPSFVSVTYGAGGSTREHTR
DTVLWVQRETNVPPMAHLTCVGHTRAEIEDIIATYVEAGIVNVLALAGDAPKDPADARPS
DYTYATDLIEHLREISDLSIGVAAHPEGHPRSPDLATDRRYLAEKLRMSDFATTQFFFDI
EHYLSLVNDLADLGVTKPVVPGIMPVTNIGQVERMAELSGAAFPSWLRERLESGRTPEDV
RRIGVDAATELCAALLEAGAPGLHFYTMNKSTATRDIYTQLGLPVA
>A0A7K1CNV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
EILHRYTESGIKSILALRGDPVGGPRAPWTPVDGGLTHADELITLAREQGDFTIGVAAFP
DGHPNSEGNFDKDIDVLLRKESLGASFATTQFFFEVDKWKRLVDALAKRGSTMPIIAGVL
PVTNVKLLTKMAELGGTPIPDSIASRFAAVEDNPEDVRKLGVEIALNLCNDLIDAGVPGI
HFYTMNSSTATSEIFESLQDRR
>A0A7K0ZAZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAIRATKYSFEFFPPKDQAGEERLWAAMEALEPMAPDFISVTYGAGGSTRDRTIRITSQI
TERTSIPTVAHLTCVGSTRGELIEILQKYKEAGIRSILALRGDPAGGPSAPWAPTIGGFN
HADQLVELAMEVGGFEVGVAAFPDGHPASNGDLAKDVDVLIRKEALGASFATTQFFFAAD
KYQRLVEALAAKGSSLPIIPGILPVTNVKQLVRMSELSGTDIPAEILVKFSAVENDHEAV
RRLGIEIATELCEQLLELGVPGLHFYTMNTSSATLEIYQKLVAK
>A0A7V9V127|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MATRFLERLAAGPTIVADGGMGVLVSSAVSRLRCPEEANVRSPESVLSLHLGFIRAGAEL
IETNTFGANRRKLRERYLDEETVKINEAAVKIAREARDVSGRDVFIAGAIGPLGDAQEDG
DDERAIFAEQAELLEGRGVDLFTVETFFDLEEVAIAIDAVRAVSSLPIVALLTFDEDAQT
LHGVSARDAAKSLSSLDVAAVGANHSAGPQASLRAIEQMGGNGKPLAVMPNVGLASLAGQ
RIVFPHATPEYFGEFAAHAQELGARIIGGCCGCTPAEIAAIKSAVDEERRPAAPLVVRER
VLLAPPPPSGGDTLLQRKLHAGEFVVSVEIDPPRGANPEGMLEIATTLRDSGRVDVVDVN
DNPRARARMSGMMASVAIERNVGIETIPHLTPRDSSIAGLESQLLGAHAEGIRNVLAVTG
DPPEAGDYPGASGVYEVDSIGLSRVITQMNAGEDFNGAEIDAPTSFFLGVAVNPAADDLE
YEVERFERKLEAGAEFAMTQVLFDFAFLDRFVERLGRPCPIPLLIGIFYVRSYQLALRLH
NEVPGIVVPEHVQARLRDAGPNAGDVGLELAQELLEASRERAAGVYVIPPFRQPLAALDV
LA
>A0A8G0Y7J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aneurinibacillus thermoaerophilus|TrEMBL
MTMPKESLKTYLKDHLLIGDGAMATWLYQLGIPIGVCYEELNLSNPELIRAVHRSYYEAG
ARFIQTNTYGAHRDALARHGLQDKVTRINRVAVQVAREAVKDDAYVVGGIGSINAGRVRD
VRMQNYREQFEEQAAALLMGGVDAILLETFLDLDELLLALDVIRPLTDVPIVAQLATIEV
GRTRDGHTLTRAFAELKKAGADVVGLNCRLGPAEILRSIENAVVPEDTPLSVFPNAGRLA
MSDGQYSYASVPQYFGENALRFRAQGARLIGGCCGTTPEHIRVMAQVLAEREPLPRVNPV
VDTQEEAEPLIRIAPPTRKQGIVETVAHRHTVIVELDPPRDLDTEKFLRGTAALQDAGAD
AITLADNSLATTRMSNMALGSIMKAKFGAEPLLHIACRDRNLIGQQSHLMGLHALGINQV
LVVTGDPARFGDLPGASSVFDVSSFDLIRMIKQLNEGYSFSGKPLKQRANFVVGAAFNPH
VRQFDAALRRLEKKVEAGADFIMTQPLYDRESIERIYEGTRHLDIPIFIGIMPLTSSRNA
EFLHNEVPGIRLSDEARTRMRRYEPGEEARREGVAIARELVDIAMEYFKGIYLITPFFYY
EMTVELTRYIRDRSRVVLQK
>A0A399M0F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas monteilii|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDML
PLDALASFGNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DGDKHQEAMHWMRRQATPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETVQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGIHELKQLLALEARIEHWQARIHTLDQWAPA
WRASWQMPGLPAVTFHPPQAGWRQGESRVDASLKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPLWSTPVGAQVLHKAERAVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAPQTP
RRLSPQPTPRSQPES
>A0A6I3BRG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAGHFLSRLNDGPPIVADGGMGALIAAAVPRLRNPVEANLRSPDAVVSLHASFINAGAEL
IETNTFAANRHKLASYYLDDEFELINSTAVKLARDAREMTGRDVFIGAAIGPVGENIPSE
QRKSIFAEQADILAGRGADLFMVETFYDLAELEDAVTAIKEVSNLPIVALLTFDEGGVTL
AGVTAKEAADRLSALDIAAIGANHGAGLLAALTALEQMKAEGRALAALPNIGLASLSGGR
VVYPHATPDYFVEFAAHARDLGARIIGGCCGTTPTEIAAIRTAIDEARPARSELTLAERD
IVVALGEEARETRLATALREKQFVVSIQLDPPLGGSNRGLLETSTAIADSGLVPFVDVND
NATARAGMSSLMVSGAIERATSLETIPHLTTRDMTILGLESMLLGAHAEGVRNVLAITGD
PPEIGDYPGSQGVYEIDAIGLTRLISGLNRGEDFNGRPIDAPTSFFVGVAVNPTADDLEA
EAERFRQKVEAGAKFAMTQIVFDLDHIDRFGELLGGWPIPVLAGIFPVTTFRLALRLHNE
VPGILVPQELQDALDAAGPNASEVGFAHARELLAACRGRVDGVYIVAPYRRPTAVLDLLS
SL
>A0A7X8H8N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MSWLKQVLQSGHFAVTAEVGPPKGSDPQVIRKKCDLLKGFVDAVNITDNQTAIVRMSSFA
SCLIAKDQGIEPVMQMVTRDRNRIALQSDFLGACALGIPNLLCLTGDHQSMGNHPQSKNV
YDIDSIQLLQIFKNMRDQKVFQNGEEVKGEIHVFLGAGESPYADPLEFRALRLAKKIAAG
AEFIQTQAIFDVDIFTRWMEEVRRLDLHKKSFILAGVIPVKSAKALRYMKNEVPGVVIPD
SLIERMEAATDQKAEGVEVCIETIQKVAKIEGVSGVHIMAIAWESIVPEIVQRSGLLPRP
VKGEITSS
>A0A7V3BUY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTGPARSGLHALLLSGEFVVTAELQAVDSADPAAVHELADLLRGKVDAVNCTDNSAAHAH
LGPLAAAHLLLDRGVEPILQLTCRDRNRLGLQADLLGAAALGVRNVVLMTGDDVSAGDHP
EAKPIYDLDSIHLVRIARIMRDEGRYLSGRPLEVPPGYLIGAVENPFAPPLEFRPMRLGK
KVEAGAEFVQTQICFNVDKLRLFMARCGELGLLDHVWILAGVFIPRSARAARYLRDQVPG
VDVPETVIERMEAVPEHRQGELGIEIALEIVEQVRGIPGIRGVHLMSIRNETGIVRLIER
AGLLPRPTTLAAPVA
>A0A7K0MW95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRSLKSDGSKALTYSFEFFPPKDVEGEERLWAAMSQLESIAPDFISVTYGAGGSTRDRTI
RITSEITARTHIPTVAHLTCVGSSRAELLEILGKYRDAGIKSILALRGDPTGGPRAPWSA
THDGLNHADELVTLAAEFGGFTIGVAAFPDGHPSSRGDFNKDVEVLLEKEKRGATFATTQ
FFFSADKWKSLIDKLAAKGSSMPIIPGILPVTNVKQLNRMAELSGVPIPGHISDAFIKFE
SNPEDVRKLGVEIATELCNDLLEAGAPGLHFYTMNTSSATREIYSHIKDER
>A0A6I3HE51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSDYLRTTTFSLEFFPPKDSAGEDRLWQALAQLQPLKPDFVSVTYGAGGSNRDRTIRVTT
EITKRTSIPTVAHLSCVGASKSDLTEILNQYMNAEIKSILAVRGDPEGGPKAKWEKVSGG
FDYADQLVELAVATGNFEVGVAAFPDGHPASNFDFEKDVDVLIRKEELGAKFATTQFFFE
SSKWHQLVERLAKRGSTLPIIAGILPITNLSQLNRMTELSGVQIPKKISKRFEGVENSSE
DVRKIGIEIATELGQELIDLQVPGVHFYTMNSAESTLEIAKNLGLVS
>A0A7K0W2B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVVRTSYSLEFFPPKDGEGEARLWDALENLQSINPTFVSVTYGAGGSTRNRTIGVTEEVT
HRTKIPTVAHLTCVGSSRQELISILHMYKAAGIKGILALRGDPVGGPRAPWTPTSDGFTH
ADELVQLIHEFGGFDIGVAAFPDGHPGSDGDSKKDIDVLLRKEFLGAQFATTQFFFEVSQ
YVKLVDALQARGSTMPIIPGILPITNVKQLQRMAELGGTPIPPQVAKSFGAVEHDPRAVH
QLGIELASQLCEDLLSAGAPSLHFYTMNSPTATLEIYGNLNSAD
>A0A538I1Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPRVSRFLERLAAGPPIVADGGMGALISAAVPRLRSPEEANVRAPQAVVSLHLGFINAGA
ELIETNSFGANRRKLAAHYLENELETINSTAVRLAREAREVAGRDVFIAGSIGPLGESAT
RRVRTDLFAEQALVLEGRGVDVFAVETFYDLEELEDAVLAVRSVSSLPIVALMTFDETAE
TLAGVTAAEAAERLNNLDVAVMGANHGAGLMAALAALEQMGGDGKPLAALPNIGLASLAG
GRVVYPHATPDYFAEFAAHARDLGARIIGGCCGTTPAEIAAIDEALAEERKPRARLEFAE
RELLVSLGEELLETGLARALREREWVVTIQLDPPLGGSSKGLVELALAIGESGKAGYVDI
NDNATARAGMSSLIVSATIERQAGIETIPHLTTRDASVMGLESMLLGAHSEGVRNILAIT
>A0A7V9DG93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPSRFEERLRDGPPLVADGGMGALISQAVPRIRCPEEANLRAPESVVALHASFIRAGAEL
IETNTFGANRRKLAGHFLEDELERINSTGVRLAREAREISGADVFIAGSIGPLGEVERPE
PAEQTLLVREQAELLEGRGVDLLMLETFFDLDELVAAIEAVRAVSALPIVALMTFDADGQ
TLSGVSAARAAETLGELGVAAAGANHSAGPAAALNALAEMQREGLVLAALPNVGLASLAG
SRVIFPHATPDYFAEFAAQARRLGAGIIGGCCGTTPAQIAAIRSSIDEDRVPAAPLVVRE
RELADAAEAEPEETELARMLREREFAVSVQLDPPLGGNDRALIEAGRTLRESGKAHFVDV
NDNPRARARMSGIMASVAIEQACGIETIPHLTPRDTAIAGLESLLLGAHAAGVRNVLAVT
GDPPEEGDYPGARGVYDVDAIGLTRIIVGLNRGEDYHGRGIDAPTSFFVGVAV
>A0A504X804|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania donovani|TrEMBL
MSRPNVKGSAVGSRNLNSTSVERNTLRSDGKLSLENIMLQFLCGEQLRLEYAMEIVQQAA
LVLRTEPNTLSINDTVVVVGDIQGQYYDLVKILAACGSLDTTKYLFLGNYIGNGGFNLEC
ILFLLAAKVAHPHSIFLIRGSNESKFMADVLQLGKECQLKYSSTLLPQILSAFNCLPLAA
IIRKKFFCVHSGLSPDVSHVDDIALIHRFRHIPTRGAMCDMVWSEPDWDTNNQLYNNVEE
PSGETYVPRLGLFETRPLFITNKQRGLSYVFNFACAKRFVSANNLLCIIRAHEVHELGFK
LAEALQRRINYAIENQMAPPETNYISELLAASLALDNSNEQLRLLDYRWQTYLDKQYVQS
QHLDEFLEGLISGTMKQAVGNSRPFVSFEFVASTTEDGAIKLHETAERLPALDPLFCGIT
WGNHLRTAETSIEPRTRGTDVGSTAAAAGAHDSSREEADATTSTFLAFIAAAPSSSSSGS
VFPHAVDLIRFVHQHFGDYFGMVVAASDDAAAWISARRDTELLFLKKKLSAGADYVVTQG
IFDVDVRQLKLFGVHRISGAADLRRRIESSKTNDSEVKYVVVAFQQPLHKRLLARGCGGV
YFFHREYGSPSYMMYAAHRRGTMEKRWNALLVSPHSGTLALGEAGVYHARLLLGSRPKPC
TQFPMIQGMAELQTALTELSRIFQAFLDGRGTRPYADELPGETVYVEHLLKLPNAQGLYT
INSQPPVNGVPSPDSSYVYQKSYVEFLCHLPSAPIVFTTLDKCPELQYTAMSAQGNVARV
TAITWGVFSRARGDSNPLSPPWTRFARVGVAFAMWAAPFPPNDVPTVAHYIQTEFVLVRV
VDNVLQEPLTPLEHAVVEICPEIPLLTLLDATQPHPKSSLTFAPDGDALMNALGQFVRAS
>A0A443JPZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinirhodobacter populi|TrEMBL
MTNTTDQKPQATNVPAVSFEFFPPQTLDASFRLWETVQALAPLRPDFVSVTYGAGGTTRK
LTHEAVATIHKNYGLTVAAHLTCVDATKAETMEIVEAYHQAGVTEIVALRGDPPKGAPRF
TAHPEGFASSIELIEALARDGRFTIRCGAYPEPHPEATDSLADVRWLKRKTEAGATSAIT
QFFFEPDTFFRFRDACVREGITAKLIPGVLPIQSWKGVKGFAARCGAHVPAGFESRFEAA
IRDGREQELSVELCVDLCEKLMAGGVDHFQFYTLNRPQLTQKVCAALGVTADRRLAVA
>A0A537VLV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSWRFWRRWRASGLTEEQRAALKSLVADARYELIPLSSALEHAAALPPGSQVTVTASPSH
GIEATFDLADAVAAQGHDVTPHLSAHMLRDRAHLADLLERAQANGLRKVFVVGGDTRDRG
ELHDGLMLLRAMDELGHPFEEVGVPCYPEGHPDISDERLLEVLREKQRYANAMTSQMSFN
PAAVTRWVGEVRDAGISLPLHLGVPGVADLPKLMRIAARIGVADSARYLKKNKQLLGHLV
RGGSFGPDEFLEQLAPMLADPVADVRVLHVFTFNQVEQTAAWQRGMLDELSA
>A0A4Y7XFY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkanindiges illinoisensis|TrEMBL
MATSISFEFFPPKTDVGAEKLIVVHQELQQLNPQYFSVTYGAGGSTRERTLSTIDALHGQ
GAPVAPHLSCIGDDKARIAELLDIYKAKGINRLVALRGDLPSGQVGLGELPYATDLVRFI
RDHSGDYFHVEVAAYPEMHPQASSFDQDIERFAEKVRAGANAAITQFFFNTDSYFYFVDR
IKQLGIDAPIIPGIMPITNASNLIRFADSTGAEIPRWIRKQLAAYGDDSASIRAFGHEVV
VKLCQRLIEGGAPALHFYTMNQTEPTRQLVKDLGLA
>A0A3D5DVX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSQPAFEIICEIEPPTRPDLKHVRHQIGVLSPVADAFLIPDNHIGRATVSSVAVAHEVEA
MGGRSIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVHGDKPTTGGRTSELTVRSMIEEA
RGCAGDPVFTTAPRWRIGVAAGLRPLPQWKLEADFVLVQVSYSVEALLRWRDANPADIPV
YAGVMVLASQAMARRMAAAVPDIEIPGWLEEKVAADPMAGVDAVCEQIQQLQDSGAFDGV
HLVPVSRYRQVAARLEAQRRNGDG
>Q2UA39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus oryzae (strain ATCC 42149 / RIB 40)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNRDFTFAVDLVRYIRQKHGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYL
VEKTQAGADFIMTQLTYDIEAYTRFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVQIPPQILSKLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLRGFHFYTLNLEKT
VSFILERCDLIPPYSEDFDAIEEGGDISAMDGAHLRSLTRRRASSINSLPHNRVIVDKLH
ASEVSSKASVSHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSS
GLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFF
CPSKDYHSILKPLLQKHGHEKLAWFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWG
VFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNDIKDDVWLVCVVG
QDFGAGTEMGSEEEEDEKKFMWRVLLNAKK
>A0A537YIL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
SMTAMAHLTCAAHTRAELEEIVGRYRYAGIENVLALGGDPPADLDLPCGELAYAVELVRL
ARGVGDFSIGVAAHPEPHPASPTRELDRLHTAEKLSEADFAITQFFFEPEHYFDLVGALH
AHGVDKPVIPGIMPVTSLAATKRMAEMQGSEFPRWLYDR
>A0A537WLR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSETPGHLGRILRSGRFCVTAEVVPPRSADPAAVVAQAKELVGYADAVNVTDNPASAAHM
APLAGVAVVADAGIEPILQLTCRDRNRLALTADLLGGWALGARAVLCLSGDPAARGDHPD
AKEVYDLTVLDLVGLAAGLRDEGRLLSGATIEGPPRYLIGVADLPLAAGYDPTRLEAKIS
AGADFVQTQIVYDVEAFTAWADGARSRGVFDRVAVIAGVAPLRNARQARLVASLPGVSVP
ADVLRALEEAGADAETEGTRLAILIVNGLREIPGLAGVHLMGLGQESAVRRVVEGAGLLP
RPVAAP
>A0A3D3DCB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MNLREKLGANKFVVTVELDPPKTLNLDKILREVNSANFKKLVDAVNVTDCPLAKLRMSPI
ALSHIIQEKIGLEAIFHITCRDRNLLGLQAELLGASALGVKNILALTGDPPEMGDYVRAT
GVYDVDSIGLTKMINGLNNGYKYEDGELMDRTDFFIGAAVNPTASDLKKEVERFEEKVSA
GAHFVQTQPIYDVGLLEKFLKLTAHINVPKIIGIMPLKSYKMVEYLNKNLPGIFIPTRVK
ERMKGKDVEEGIKIAQEIIDKIRKLKGVAGIHIFPLRDMDLVCRLLN
>A0A354SEC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTHAAKSANLAEVLRTGGQSFSFELFPPKTDEGERALWQTVRELERLSPTFVSVTYGAGG
STRDRTVRITEEIAEQTTLMPVGHLTCVSSTREEIREVIAEYAAAGVRTILALRGDPPGG
PSAPWVPHPDGIEHADELVALIKSLGDFTVGVAAFPDGHPSSIDHEVDARVLAAKQDAGA
EFAITQFFFRARDYFDLVERAQSHGCTIPIIPGLMPVTNVAQISRFAELSGAAFPSELLG
RFEVIKDDENAVRELGVEIATSLSDELLGQGAPGLHFYTLNRSTSTARVYESLGLGSR
>A0A538HVK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSRLEQAIEAGRFVVTAELLTVDTGGLDAVRERFAPYTDWVDAVNATDNTAAHAHASSVG
VAIALAQLGMEPVMQLVCRDRNRLALQADIMGAALHGIENVCCLTGDDVTAGDEPEARRV
FDLDGPQLVATARSLASGHYLSGRTIDPAPHLFIGAVENPGAPPYEYRVERALKKVEAGA
RFLQLQLCFHTDMLERFMAEAVAQGLAERAAILPSICLVRSPGALRFVNDKVPGIEVPQE
LIEHCEQAADPEAECFALGCELAEHARSLPGVRGLHLISFRREAGIARLCQRLGIPTRAE
RETSGDSSRVPV
>A0A4P5RU56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKWESTAGGFDHADQLVTLASSMGFEVGVAAFPDGHPASMGNFEQDIKVLLEKERCGASF
ATTQFFFDVKGYINLVDEIRARGSKLDIYPGILPITNFAQLKKMSELAGSPIPSEVQRRV
EAAGDTPADVVKVGVDIASELSKKLLDYGVPGLHFYTMNSAAPTIEIIKRIGLR
>S9ZTB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera terpenica 58Eu|TrEMBL
MSTEISIEFFPPTTAEGAAKLDLTRARLAALKPAFFSVTYGAGGSTRERTFSTVKDIAAA
GHEAAPHLSCVGSTRDSIREILHEYTEAGIRRIVALRGDLPSGVVDPGEFRYANELVEFI
RAETGDRFHLEVAAYPEWHPQAKSPKDDLLAFKRKADAGANSAITQYFYNLDAYLHFVDA
AHKMGVNIPIVPGIMPIGSFSKLARFSDACGAEIPRWMRKTLESYGDDADSIRAFGLDVV
TRLCEKLLAEGAPGLHFYSMNMAGPTTEICRRLGLTA
>A0A523CGC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MHARAHPASPHRTGPRRDEAAPRQGLLQEAQAGLGQSSREEGWCQVSRLRDALERGEFVV
TGEIAPPLGTDLTAMRRSIETIGPHCHAINITDNQGASLHLSSLAASRAALEMGFEPIFQ
QTCRDRNRLALQSDLLAAWTLGLENVLIVTGDDPRSGDHPEAKGVFDLDSTQLLEVAAQM
NAGTDMIGRPLKGGTDFYLGAAMFPEAEPWDIQLLRAARKVEAGARFFQTQAIFDITKLE
RAVEELRPLGAKVIAGVLVLRSARAVDFINKRLAGLMVPEAIGARIKSADNAAAEAIKLA
TEQVRAAREVADGVHIMTLGLDDAVPEILEGAGLG
>A0A3A4WBR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MALADALNSGKFVVTGELTPPKGVDTADMVAKAKVLEPVVDAINVTDNPSARMQMSSLGG
CLALIDAGFEPVYQLTCRDRNRLALQSELLTAASQGVRNVLALTGDHTKFGDHPQSKPVF
DLDAVQLLQAIEALNGGRDMSGNELKGATSLLAGASVAPEAEPWEAQRIKFEKKVEAGAT
FFQTQAVFDMQKLERLARVASKLKVKVLAGLILLKSARMVEFLNAYVPGIIVPEGVVGRL
AESDKPSETGIEIAVEQVARFKELCDGVHMMVMGAEDRVAEILERAGVTAVRA
>A0A538KV32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPDRFEKRLEHGPPVVTDGGMGVLVSSAVPGLRCPEEANIRAPESVVSLHASFINAGAEL
IETNTFGANRHKLRSQFLEDEVAAINETGVKLAREAREISGRDVYVAGSIGPLGELGGLA
ADERGPVFAEQAALLEGRGVDLFMVETFFDLDELTTAIEAVQGVSGLPIVALLTFDEDAE
TFGGVSARDAVERLSAYKLAAVGANHGAGLHAALAALEAMGDGRPLAALPNVGLASLSGG
RVIYPHATPEYFAEFAAQARALGARVIGGCCGTTPTEIAAIARAVEEERQPTAPFAAAER
DLVVAAHERPEETELARKLSAGEWITCVELDPPKGGTYESMLAVTKTLKDSGAVGFVDIN
DNPMARARANALMAAIAIERTCAIETIPHVTPRDTSVMGLQSQLLAAHAEGVRNVLAVTG
DPPHVGDYPGSRGVYEVDSIGLAQVVTRLNAGEDFNGKAIAAPTSSFLGVAVNPSADDLE
TDLDRFRQKLEAGAQFAMTQALFDLGYLDRFEELIGGWPIPILVGIFMVRSHQLAVRLHN
EVPGIVVPEDVQNRLRDAGPRGAEEGLALARELYTEAREKSAGVYVIPPFKQPEAALELL
GIE
>A0A2S7U2Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubritalea profundi|TrEMBL
MHISDILSQDGPSLSFEFFPPRTKESFDALYQVIAELEPYKPSFVSVTYGAGGTTRDLTH
DLVLRIKETTGIPPVPHLTCIGHTEAEIDAILQRYANAGVSNILALRGDPPRDQPDYDRS
NDDFKFAADLVAFIKKFNQSGRHPDARGFGIGVAGFPEGHPTTPNRVLEMEYMKAKVDAG
ADYICTQLFFDNHDFFDYRERCQIAGITIPIIAGIMPVTSVKGMSRMAELAEGARYPAKL
LRALERANGNPESVERIGTHYAAQQCLELLDGGVDGIHFYTLNKSKATREIYASLGLSQA
LA
>A0A2M7YZI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium CG_4_9_14_3_um_filter_51_5|TrEMBL
MHISEVLRTHNPAISFEFFPPKTERAFQELFETISALMPLKPAYVSVTYGAGGSTRERTH
DLVVKLQRETDLTIVSHLTCVGSGREEIRRILSKYQASGIHNIMALRGDPPKGSTDAQIP
EHGFQFASELVWFIKQQFPEMGVGVAGFPEGHPGTPNRLQEMDNLKRKVDAGADYICTQL
FFDNRDFFDFCERCEVVGIKVPVIAGIMPIISRKGMARMSELALGARIPAKLLRAMDRAE
NDDYAEGVGIHWATEQVVDLVDHKVKGIHFYTLNKSKATLKIYESLGIRSSESLQHPVE
>A0A4P5S986|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSSRKSAPSLGSVLVGGGHSFSFELFPPKTDAGEQALWQTVRELEALKPTFVSVTYGAGG
STQDRTVRITKQIAEETTLLPVAHLTCVEASVEDLRRVIAQYSDAGVSTIMALRGDPTAG
PEASWVQHPGGLQHADELVALVRSLGAFSVGVAAFPEGHPESNDFEDDARVLAAKQDAGA
EFAITQFFFRAEDYERLVARAAVHGCTMPIVPGLMPVTNVAQIERFAALSGAEFPAELAE
RFTRIQDDQPAVHEMGVEVAATLGEQLLGLGAPGLHFYTLNRSTSTREVYKALGLSAESP
I
>A0A431L4X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MTTAVSFEFFPPNTPVGVEKLKGVVQQLGELSPQYFSVTYGAGGSTRDKTLSAVMDIAAA
GFEAAPHLSCVGSTRENIAEILATYRAQNIHRVVALRGDLPSGTATAGEFRYASELVSFI
RETQGADWHIEVAAYPEVHPQQRYAAKDLQHFADKMKAGADGAITQFFFNADAYFHFVEE
ARKLGVTQPIVPGIMPFHNYARIAQFAQRDGIDIPRWVQLKMEGFMDDAASIRAFGLDVI
TRLCERLIAGGAPGIHFYTLNQSPLVLELCKRLGLGAQV
>A0A3D3SZ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
LQSYGDDAASIRAFGHEVVTDLVDQLLTAGVPGIHFYTMNKADPILKIAAALKLDGRDGL
GRAG
>A0A0E2P5R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pseudopneumoniae 22725|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQILDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKSILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A0J5GGP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vogesella sp. EB|TrEMBL
MTERNRTFSFEFFPPRTPEGVAKLRTTRQQLAQFKPEFFSVTFGAGGTTRDGTLSTVLEI
RNEGYAAAPHLSCIGSTRDNIRSILNEYRNHGIRHIVALRGDMPSGMVEAGEFRYANELV
AFIREEHGDHFHIEVAAYPEFHPQAKSAEDDINNFVRKVNAGANSAMTQYFFNADSYFRF
VDEVQARGVDIPVVPGIMPIANFGQLCRFSDMCGAEVPRWLRLRMQAYMDDSASIRALGL
DVVTELCDRLLANGAPGLHFYTLNQAGTVSTIWQRLGL
>A0A542WHD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SLBN-134|TrEMBL
MALGTASTRTDRARTVRDILAAGKKTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVSHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PEALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A5X8YL58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Kisarawe|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A562KIV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium wenxiniae (strain DSM 21828 / JZ-1)|TrEMBL
MTLSFPSVEEARRALDAPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLGPKFV
SVTYGAGGSTRERTHNTVARIAKETPLAAAAHLTCVAASKDEIAEVADAYWDAGVRHIVA
LRGDPPVAGAKFEAHPQGYQGAAELVDGLVKRHPFEISVAAYPETHPDAASAQGDLDNLK
RKLDAGATRAITQFFFEPDTFFRFRDTAAAAGISADIIPGIMPVSNFAAVQRMSAMCNTD
VPLWMGRLFEGLDTLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPEKSA
>A0A1X7M846|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|methanotrophic bacterial endosymbiont of Bathymodiolus sp|TrEMBL
MTKNNKADLFSFEFYPPKTEQGDVNLEQVHRDLAKLNPDFFSVTFGAGGSTRDKTYDTVV
KIQNSGVSAAPHLSCVASTKENIREILSNYRERGVSKIVALRGDLPSGMMSAGEFRYANE
LVDFIRAETGDHFQIYVAGYPEIHPQSNNATEDFNNFKRKVDAGADAVITQYFYNVEAYF
YFLDKCAKSGIDIPIVPGIMPITNYAQLFRFSDMCGADIPRWMRKTLECFGDDKASILAF
GEDVVTKLCQQLLDSGAPGLHFYTMNQSKPTLAVWNNLRF
>W1I1V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae IS39|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVVAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1W1VK77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus hopiensis KR-140|TrEMBL
MTRVSIELVPRSRSGLRAELEAVGRHLPGVDTVNVVDLTRYSTRSWHGCALARPHHRAIP
HIRAVDLNPAEPLPMVEVLEASGIDEVLIITGDAPADMSAKVYDVDAIRAIRRFRREAPH
IKVYAGLDPYRQSFARERDYLERKLEAGAVGFFTQPFFDLRLMDAYADLIPEHAEMWWGA
TTVLTPSSLNYWRARNHAVFPRSFEPTLEWNRTFAAQTLAFARERSHHAYFMPVKADARE
YLEGIV
>A0A1C4WWR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora coriariae|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTEAGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVSVTERIATDTTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPEGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTTHFVR
KCRAGAEFAITQMFFEADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQASEMSRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARR
>A0A1I0RE33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium wanjuense|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTPGGHASAMDLVHQINDLGRGKYLHNQDEECDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKEKVDAGADYIVTQMFFDNKKYIEFVTKAREMGITVPIIPGI
KPIATKRHLKLLPQVFKIDLPEELINEVEAAKNNEAVKQIGIEWSIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A8C4AGQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denticeps clupeoides|TrEMBL
SRPPCSSTDNTDSCSTGESSRESSRCSTPGPDADRADRLREKMRRRIESGDPWFSLEFFP
PRTSSGAVNLISRFDRMGFGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESIL
HLTCCNQTKENITAHLSKAKRLGLKNIMALRGDPLGDSWEEEEGGFSYATDLVKHIRCEF
DDYFDICVAGYPTGHPEADGYHADLKHLKEKVDAGADFVITQLFFRAETFLSFVKDCRAI
GITCPILPGVFPIQGYQSLRQLVKLSKLEVPKEIMEVIEPIKDNDAAIRNYGIQQAVEMC
KVLLDSGVVPGLHFFTLNREVATIQVLRQLGLWIEDPRRPLPWAISAHPKRKVEDVRPIF
WASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKCSKDALLQMWGEELT
SEESVFEVFTNYITAQANLSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGILTINSQP
NINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLRKYEPRVNYHIVNVQGK
NLTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEEESPSR
MIIQYIHDNYYLVNLVDNDFPLDNCLWQVIDDMFDLLDAPPEPLQ
>A0A8C0EB26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bubo bubo|TrEMBL
WHVQPKAVRSKSLSPDAHDSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRR
RQDSGDKWFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMI
IANTAVNYCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDG
FNYAVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFF
RSETFLKFMKDCQAIGITCPVIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDND
AAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAV
SAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSK
SPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQL
EKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKK
YELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALW
IEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>B0PF81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerotruncus colihominis DSM 17241|TrEMBL
MHFDRPFLFDGAFGTYYFSKTGDEAPCELANLTAPQTVLDIHREYAASGCAALKTNTFAA
NPVSIPDSVRLNEVIAAGWSLAQRAAQENGARVFADIGGICADTAEADYLTVVRHFLELG
AQNFLFETLACYQDVQRAVGLIRQSVPDATVIVSFAVSQDGYSRRGLYCRALFDQAESDP
QVDAVGLNCSCGPSHMRSLLRALGQRVKPVAAMPNAGYPSSLNGRVFFEDNAGYFAQQLS
ALYMDGADILGGCCGTTPQHIRCAAAALAAAAARPKGTGQPKPQAASATGAGAPGGGRLG
LPRKEIAVELDPPFDHDCSFVLAAASELRACGVDLITVTDSPLSRTRADSLMTAAKIRRE
AGIEVMPHISCRDKNHIALRAGLLGAAFEGIGRVLIVTGDPPMQAGTRGSDGVYHLSSYD
LIAWIHSMNSEVFADAPFLIGGALNVNAANFDAELARAKKKLSLGASMLFTQPIFSDKAV
DHFLRARQELKDCRLFAGILPVAGYKNALFLINEVSGIEIPDNVVRSLEGKTPDEAAAIS
VAYSAGIMRRVYDAADGFYIMTPLKKVNIVRGLIEEIRRYEQ
>A0A8C4FTL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denticeps clupeoides|TrEMBL
MRILAADVTPSSAGRTRRPSRIWTPVRRLARECRSSRESSRCSTPGPDADRADRLREKMR
RRIESGDPWFSLEFFPPRTSSGAVNLISRFDRMGFGGPLFIDITWHPAGDPGSDKETSSM
MIASTAVNYCGLESILHLTCCNQTKENITAHLSKAKRLGLKNIMALRGDPLGDSWEEEEG
GFSYATDLVKHIRCEFDDYFDICVAGYPTGHPEADGYHADLKHLKEKVDAGADFVITQLF
FRAETFLSFVKDCRAIGITCPILPGVFPIQGYQSLRQLVKLSKLEVPKEIMEVIEPIKDN
DAAIRNYGIQQAVEMCKVLLDSGVVPGLHFFTLNREVATIQVLRQLGLWIEDPRRPLPWA
ISAHPKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKS
KCSKDALLQMWGEELTSEESVFEVFTNYITAQANLSGHKVMCLPWNDDPLAPETNLLKDE
LEKVNRRGILTINSQPNINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLR
KYEPRVNYHIVNVQGKNLTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFAL
WIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLDNCLWQVIDDMFDLLDAPPEPL
Q
>A0A3G9J760|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus baekrokdamisoli|TrEMBL
MKPDLREALKTRILTGDGAMGTYLYQMGFPVGVSYEEFNLLRPNVIEDLHRRYYEAGARI
IETNTFSANYESLSRYGLDTDVEAINRAGVEIARSAVGSDAYVVGAIGSIRAGKRKNIRS
NQLTQSFHQQIDALLSAGADGLLLETFYDLEEVLLALRLIRKVSNIPVICQFAVEKEAVT
QDGHTLAVAFETLRLEGADVVGFNCRSGPNGIMRAIDSIHAEVKLPLSVFPNAGIPDYVD
GKYMYTASPEYFAESARKFADRGARIIGGCCGTTPEHIAAIAAALDGYQPQPVAIDLQPP
DEKQRPVITITAPSTQEVTPADTKQEPSIVDLVKQRHTVIVELDPPRDLDIRKFMDGAKA
LKAIKADAVTLADNSLAVTRMSNLALASLIQQQVGIKPLVHIACRDRNLVGTQSHLMGLD
ALDIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGVSFSGKPLKQKAKFIT
GAAFNPNVKYLDKAVTRLERKIASGADYIMTQPVYDKELIIRMAEAVKHLSIPVFIGIMP
LASGRNAEYLHNEVPGIQLSDEVRQRMAGLEGEAGRAEGVRIAEELLDTAMQHFNGIYLI
TPFMFYEMTVQLTDYVWRKTGI
>A0A6I2GM99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aggregicoccus sp. 17bor-14|TrEMBL
MKIRYRLNPSNPCFSFEFYPPKTDDGTRALLRTLEELAPLEPGFVSVTYGAGGSTRDRTV
DLVTQIKRTTGITAMAHLTCIGHDREELRAILRKLSDAQVENVLVLRGDPQAGAPGFVPH
EGGFRYASELVEFIRGEDFGFCLGGACYPEGHVETVSREEDLVHLKQKVDAGLDFVITQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQLQRFTRMCGATVPMRLALQLERVRD
QPEALMQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVGALRART
>A0A350HLC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella sp|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8C4AFK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denticeps clupeoides|TrEMBL
MVNQVQKVDGSWQSCKSDSSGASNSGESSRESSRCSTPGPDADRADRLREKMRRRIESGD
PWFSLEFFPPRTSSGAVNLISRFDRMGFGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQTKENITAHLSKAKRLGLKNIMALRGDPLGDSWEEEEGGFSYATD
LVKHIRCEFDDYFDICVAGYPTGHPEADGYHADLKHLKEKVDAGADFVITQLFFRAETFL
SFVKDCRAIGITCPILPGVFPIQGYQSLRQLVKLSKLEVPKEIMEVIEPIKDNDAAIRNY
GIQQAVEMCKVLLDSGVVPGLHFFTLNREVATIQVLRQLGLWIEDPRRPLPWAISAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKCSKDAL
LQMWGEELTSEESVFEVFTNYITAQANLSGHKVMCLPWNDDPLAPETNLLKDELEKVNRR
GILTINSQPNINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLRKYEPRVN
YHIVNVQGKNLTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEEESPSRMIIQYIHDNYYLVNLVDNDFPLDNCLWQVIDDMFDLLDAPPELEVDTVY
>D2KQI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos taurus|TrEMBL
AGYPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACS
>A0A845XN58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO3B2|TrEMBL
MTNPTKNSFRTAVESGEFLITGEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQEGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQGTDLFTGAAVDPQLKSWSGLQRRFER
KLEAGAQFFQSQLICDFDRLEKFMNQIAAGSNKPILAGIFLLKSAKNAKFINKNVPGVDI
PEEIIDRLAAADNQLQEGIKIAAEQVKLARQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSPVNDLVFK
>A0A7Y0KHX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora sp. TBRC 11914|TrEMBL
MSAATTTADRCPKRMVFGPCGGVRPAGACELDAALPCPWADPADPAPVRRWEGPTPAPTP
AAPDGLLDTAARRPVVLTDLSVPPYDVATLRDVASRLGRHSDALLVGEHHDVPDFPPTMM
AAELQRVGARPWITLTCRDRNRVVLEQELAGLAALGVEGVLCVTGDGRGPGVRPDVGRVF
DLDSTRLANLAATAGLVATSAVAPAAPPTDVRAAALAEKQRAGTSLVVTNHVGRAGELAD
FLARARAAGVDLPVIAGVAVYTDEATARGLAALPGLELDEEAVAAVLTAPDPVEAGIEVA
LAEARALLALPGVVGINLSGVASRAGWVPAAEIKAEVGRRLAQERAGAP
>A0A851CFD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calyptomena viridis|TrEMBL
MVNETQHTCSASCSSRSDGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQEAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDLV
KHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLRF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKHQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A823QTK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALADIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLIKEELHA
>A0A8J8W8Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium sp. RFL-2021a|TrEMBL
MEKEKITEKLAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGG
STAARSLELAEVCQRQLQLTTVLHLTCTNMSRALVDMALEEAKVLGIRNILALRGDPPRS
EEYNMHGEDDSNKDFTFAVDLVRYIRKQHGDYFCVGVAAYPEGHPADSFQDVQDPARDLP
YLIEKTVAGADFIMTQLTYDIEAYQRFESMLRNHESGVFKTIPIIPGLMPIHSYKILTRV
TKLSHVHLPDPIAKRMEELKHDDDAVKRAGVDIVSEIVGGMQEMKSPGPRGFHFYTLNLE
KTVSFILERCDLIPAFTDVEDDYALVEADGIVAGGVPARLRRRASSVNSQPHNRVIVDKY
SENVSSHDSVHEALANSAGQPAMLPGRSTTLQISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVSSPVARRIWGHPVERSDISTLFRRHVSGELYMVPWSEGGADEGAGL
NAETELIRPELLKLIDGRGWWTLASQPAVNGVRSDHPIFGWGPQREGFVFQKPFVEFFCS
NKDYTKILKPLFEKHGHDKLVWFATNNTGAFESSLPTQPADVDLDNLDSNPDSVNAVTWG
VFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTERFLDELKNDTWLVCVVG
QQFGAGTPRGSKEEEDEVKWMWRVLAGEAH
>A0A4Q7UTU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sediminis|TrEMBL
MTLVSTLTPAPTVTDRISVDRPFFAVEFFPPKDDQGEADLWRAIRRLEALDPAYVSVTYG
AGGSSRDRTVRTVGRIASDTTLVAMAHLTAVSHSVDELRHVIGSLAANGIRNIMALRGDP
PGKDPLDEWEAHPEGLNYADELVELCKQSGPFCVGVAAFPYGHPRSADLESDTEKLVGKF
RAGAEFAVTQLFLEPEGFLRLRDRVAALGFDQPIIPGIMPLTSEKTFHKGPELSGSPLPE
ALVKRLEPYAGDQKTFRPAGMEVTGELCERLIAEGVPGIHFYSLNRSTATTELVERLGLV
ARRAEV
>G0ETD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus necator (strain ATCC 43291 / DSM 13513 / CCUG 52238 / LMG 8453 / N-1)|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSCESIRAVLQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVKAGADSAITQYFYNADAYFRFVD
DVRAQGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A2X3CFZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIQRY
>A0A367ZCX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium|TrEMBL
MKLDFRERLKLGPILCDGAMGTMLDLYEYEELPHEIQNLINPDIVERIHREYIAAGAEII
ETNTFSANRFRLAEYHLENKIKEINIKAVEIAKMAGGNDVYIAGAVGPTGKLIEPVGKLK
RQEVHDAFKEQIEYLLEGGVDIIILETFVSTAELDEAIDAAKELTNLPIIAQKAFAEDGS
ILASNFPIEVVEHIIQKGIDIVGANCSVGPQRMYSIIKNLHRDGIYLTAQPAAGIPTLQN
GRSIYHASPEYLAKYARELVQIGVTIIGACCGSTPRHIKAIKEAIQNVELKKEKIEIKKE
PEPLESSDIELLYDSERYRKSKFARNIGKKILTTVELDIPRGLDMRHVIEGAQKCMELGI
DAVNITDGARARLRMNAIAISQLIIQKVGIDTITHFTARDRNLMALQSDLLGAYALGIKN
ILCVTGDPTSIGDYPQAKTVLDVDSIGIIRAAKAMNNGTDLLGHTIKEPTSFLIACAFNP
LAYDLELEIERLEKKIESGAEIIFTQPIYELKTLEDCLNKIQHLHTPVMVGVLPLRNYRH
ADFLHNEVPGIRIPEKVRDILKNSEKDAFKIGIQISKEFIKNAKDMVQGIYMMPPFGKYE
VIEELLSAIK
>B9STA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ricinus communis|TrEMBL
MKVIDKIKASVGASSHPHSNGGAISDSNDKVVFSFEFFPPKTEDGVDNLFDRMDRMVSHN
PTFCDITWGAGGSTADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKSNGIQ
NVLALRGDPPHGQDKFVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDMIESDG
LATPENYQRDLEYLKRKVDAGADLIITQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPIN
NYKGFLRMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKIMAHGIKTLHLY
TLNMEKSALAILMNLGLIEESKISRPLPWRPPTNVFRVKEGVRPIFWANRPKSYISRTLG
WEQYPQGRWGDSCNPSYGALSDHQFMRPRARDKKLHDEWVVPLSSAEDIFEKFKKHCLGK
LKTSPWSELDGLQPETKIINEQLGKINLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVY
QKAYIEFFCSTDKLQALLEKCKALPQLTYMAVNRGGTLLSNVGQNDVNAVTWGVFPGKQI
IQPTVVDPASFSVWKDEAFEIWTRGWASLYPESDPSRKLLEEVQSSYFLVSLVDNDYIQG
DIFAVFADL
>A0A8G1BXM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenibacillus sp. N12|TrEMBL
MVVELDPPRAPAFDRYLQAARRLQAAGVTHITIADNSLAHARLSNVVAAVLLRQAFGLSP
VVHLNSRDRNLLAQQSTVLGLFAAGVRHFLLISGDALALGDHPDGKAVYETDSLGLMERF
RGLRAGVDFFGRPLEGPLDVCYGGALNLGRTLGPHLRRLAAKADRGARFFFTQPIFDPAD
LERLLEARALLGGRGTLYIGIMPLISAASARFLAGVPGMNVPSDVVRALEPYTGEAAIEA
GLAQAEALIERAFELGWTRFYLITPYLRASTTARLARFVLARRPPTGASPADDGSSGVGT
SARPGASVGVEAAPELGP
>A0A2N9L455|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfotelmatomonas gaucii|TrEMBL
MSRFAEMFADRPILADGAMGTVLTARGVFINRCYDELNLSDPGLILSVHEEYLQAGAEIL
ETNTFGANRFRLTRHGLNGKLEEINAAGVRLARRAVEHLKERQGGQAWVAGSVGPLGVRL
EPLGKTGLEEARDAFAEQIGILARNGVDLLIIETMPALNEAHQALEAAKAAAPHLPVLVM
ITVDDESEGLDGSSPTQAAALLTEWGADAVGVNCSTGPATVLTAIEAMRGATTLPLAAMP
NAGMPRAVEGRNIYLVSPEYMASFARRAIAAGAQIVGGCCGTTPNHIRAMRAAIRAMDEQ
PHIEVAGSAPAVSKETPPAPLAQRSRLGALIAEKKFITMVEFVPPKGINCAKEIEGAQLM
ARAGVHAIDVYDAAQASARMSGQSLCIQIQQHTGMETILHYTCRDRNILSIQSDLLGASS
IGLHNILCVTGDPPKQGNYPDASAVFDVDSIGLVNIVSRLNHGLDIGSNSIGVSTNFTIG
VAASPGMPDIENELRRFAYKVEAGAEYAVTQAVFDLRLLEEFLERIREHRIPVIAGIWPL
TNLRNAEYMKNDLRTGMPEEIMLRMAQAGTGEAARAEGIKIAQEMLTAVRPYVQGVQVSA
PFGDYDAAAEVIASALPPAAPRKE
>A0A7L3JQM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassarche chlororhynchos|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEEDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPDAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKLSNMYITPLQTLFF
XYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A1D8SME3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces olivaceus|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPGADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVTHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPQLSNAAF
PAELKERILTAKDDPAAVRSIGIEFATEFCAALLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A0Q5ZXV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. Leaf405|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPSVGGHASAMELVNQINDLGRGKYLHNEEKECEEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVKKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEELINEVERAKNNEAVKQIGIEWAINQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A418NEF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagerythrobacter aerophilus|TrEMBL
MSPTFNQMQEARMALDAPLFSGLPGDIDVSFEFFPPRTEKMAQTLWESVKTLEPLGPRFV
SVTYGAGGSTRERTHEQVVRINRETNIPAAAHLTCVQATREEIDEIARHYWESGIRHVVA
LRGDPPDGQSRYTPHPGGYANAAELIAGLTAVAPFEISVAAYPEVHPDARDAEADLDNLK
RKLDAGATRAITQFFFEPECFFRFRDKAVAAGIDSEIVPGVMPVMSFASVQRMAGLCGTA
IPAWMEGLFEGLDERPAARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRPKGIPDDC
>A0A1F1HB79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC064H09|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLTKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKDQAPQFDIIGACYPEGHPDSANQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNADTARHIHEATHSLFKHHSQVGAL
>A0A1Y1CJS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labilibaculum antarcticum|TrEMBL
MKVIELLNQAIENKTTHFSFELLPPLRGNSINKVFNTIDKLKEFDPKYINITAHRDEMVF
SESASGIIEKKLTRKRPGTVAVAAAIKNEYKITVVPHIICSGFLPEETENALLDLNFLGI
YDLLLLRGDSSSRHEFISSEGEHKYAVDLIKQVDEINKGNFLDGTHVEPFATPFSYGTAG
YPEKHEEAPNLDSDIYWLKKKVDAGAEYIVTQMFFDNQKFFDFVKKARAAGITVPIVPGI
KPISALSQLTVLPQIFKTDIPEALAAEVRKCKTNDEVKQVGTEWGIQQGKELIQHGVPSL
HFYTLMASNCVRDIAKAIY
>A0A1L0B6B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hanseniaspora guilliermondii|TrEMBL
MSNILNISNLYSKKLTTYGSKPSISLEFFPPKTKTGLDNLIKRIERLTIAVQPIFITITY
SQLNNKKTLDLLEMIIKNNNDVFKNVNICCHLTCTNSSYQVINETLDKCLELGIKNILAL
RGDSVENDTNNNTDFRYAVDLVRYIKKRHGDDFCIGVAAYPEGHYNNEYNSNTNSYISSQ
SFREDLVYLKEKLQAGASFIITQLFYNVDKFLQFYNEYKSIIPDYKKYLMIPGIMPINNF
MIFNRATKLAHVDIPKHIIDRFPIDIRNDDDQVRNIGVNIMVEIIERIYEKTNHEVNVFH
FYTLNLEKSIAQIISKSTLLSQILEDSDSDESDSSYEDAVYSTDDEVDEGEETSSKTLNS
NIKTSDINNSTSKPLHTSEDIKLALRKDSDMEEDEDIIFDSDSDEQLDEPVDIKTFKELS
IDPNSDKEIAPSSEHYSTKVQQYNKKLTNPPKRKRTRSSQSSFTSGLLSSLDKNLKRKPI
KQHKKLFREISKGTNPQLGKTILWDEFTNGRFGDSRSPAFGEMDGYGPTLKVASHKAIEY
WGNPSNIMHLIEVFEQYLLNSIPVLPWCDLVGITPETGLIQEQLLELINDKQMLTTSSQP
SCNGISSDDKIFGWGPSNGKVYQKAFVEFFISKEKWKILRERLDKNEKFGYYCGNTRHFE
TSFKNNKDSGSSCVVTWGVFPNSEVQQTTILEEESFKAWVEEAFQLWKEWAKIFPKNSNS
QNFINQCYDNLLLVEVVYHDYSDFDGLWNFLLEDDGNEVDMN
>E1YDF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
METWTGRRPPQNYQRGFGRMKTESVLEKVLKSGNLAVTSECGPPRGAVPEKVRQKAELLR
GYVDAVNVTDNQTAMVRMSSFAAGVILRQMGLHPILQMVTRDRNRLAMQSDIIGAYSHDI
NTMICLSGDHPKFGDHPMAASVHDIDSIQFVQMVKKMRDEGKFQGGADIENTPKMFIGAA
ANPFADPFELRVARLAKKVAAGADFIQTQCIYNLDKFEKWMEGVRNRGLHEKTYILAGVT
PIKTVGMARYMKNKVPGMDVPQEVVDRMAGVPKEKQAEEGIKICVETIERLKQVKGVAGF
HIMAIEWEHKVAEIVERAGLYPRPDIGI
>A0A2N1KJM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Siphonobacter sp. BAB-5404|TrEMBL
MKVTEHIEQANGKSLFSIEIIPPIKGQSVTELFDSIEPLMEFKPPFVDVTYHREELIEKK
HPSGLIQKVPVRRRPGTVGICAKLMERFKVDPVPHVICGGFTKDETEDFLYDLHYLGIDN
TLVLRGDPEKSAGVFKPKEGGHAYATDLISQVVDMNSGRLLHEETEAQPTNFCIGVAGYP
EKHFEAPNHANDLRYLKKKVELGADYIVTQMFFDNQKYFDFVKRCRAEGINVPIIPGLKP
ISTKKQLTVLPRIFHLDFPEELVKAVEDCKNDQQVREVGVEFGIKQCKELLDFGVPVLHF
YTMGKSDSVKRIAEAVF
>A0A1E5NIR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira hampsonii|TrEMBL
MNNDVENFIKKLENKDKYTFTLEISPQAKYDLGYIEEKINRADISNYIDGFVVTDSPFAN
LKISSILAALQLQQRLNNNKPFITTQTMRDRNSIAIQNDLIGANYFDIRMVLAVTGDAIA
NGNQKQAKAVFEGNSQLLINIINDLNKGKSLGEFNFKEPLKHIYPFCVINSYAKNNDTLK
LRLAKKANSGVKAIFTQPIYEAERLELFLKWIDELPLKEKPILVPGFFPVLTYKTAYFIY
YKLPGAYIPEIWLNKLKEASDKSPEEEKKAAVELSTNLFNSMIKKHKKMHIMSMNNYDFV
VELLKNI
>A0A421AYX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinokineospora cianjurensis|TrEMBL
MTTVLERLRGADPVFSVEFFPPRNDDEERLLWRTIRELEPLDPAYVSVTYGAGGSRRDRT
IRTTGRVATETTLLPVAHLTAVDHSIAELRNVIGWYASVGVRNILAIRGDPPGDVNGEWV
PHPLGLSYAEELVRLVRELGDFCVGVAASPYGHPRSTDLATDTEHLVRKLRAGADYAIAQ
LFFDADDFLRLRDRVAARGCDALLVPGVMPLTTIRTFTKAVELAGVPAPTRVVSRLLRWE
HDAPSFRKAGIDLATELCADLLAESVPSLHFYTLNRSKATREVVSRLGLVRARV
>G4E8Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiorhodospira sibirica ATCC 700588|TrEMBL
MRSQQAHERAFSFEFFPPKTPEGAAKLSQTWQTLAELQPRFFSVTFGAGGSTQERTLETV
LNIQREAGIDAAPHLSCIGSTRNHIREILHTYQNHGVSHIVALRGDMPSGMHGEPGELRY
ANELVRFIREETGDHFFIEVGAYPEFHPQATSSSKDLENFRRKVEAGANAAITQYFYNPD
AYFSFVDACEKLGLSLPIVPGIMPITNYTQLARFSDACGAEIPRWIRKRLESYGDDMASL
RAFGEEVVTRLCEQLLQAGAPGLHFYTMNQTGPTLAIWRNLNLSPCD
>A0A1D6L981|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zea mays|TrEMBL
MMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDKFVQVEGGFACALDLVQHI
RAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLKRKVDAGADLIVTQLFYDT
DIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPSEITAALDPIKDNEEA
VRQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIGILMNLGLIEESKVSRPLPWRPAT
NVFRVKEDVRPIFWANRPKSYLKRTLGWDQYPHGRWGDSRNPSYGALTDHQFTRPRGRGK
KLQEEWAVPLKSVEDISERFTNFCQGKLTSSPWSELDGLQPETKIIDDQLVNINQKGFLT
INSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVN
KDGETFSNISPNAVNAVTWGVFPGKEIIQPTVVDHASFMVWKDEAFEIWTRGWGCMFPEG
DSSRELLEKVQKTYYLVSLVDNDYVQGDLFAAFKI
>A0A1D6L979|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zea mays|TrEMBL
MPINNYKGFLRMTGFCKTKIPSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILATGIKT
LHLYTLNMDKSAIGILMNLGLIEESKVSRPLPWRPATNVFRVKEDVRPIFWANRPKSYLK
RTLGWDQYPHGRWGDSRNPSYGALTDHQFTRPRGRGKKLQEEWAVPLKSVEDISERFTNF
CQGKLTSSPWSELDGLQPETKIIDDQLVNINQKGFLTINSQPAVNGEKSDSPTVGWGGPG
GYVYQKAYLEFFCAKEKLDQLIEKIKAFPSLTYIAVNKDGETFSNISPNAVNAVTWGVFP
GKEIIQPTVVDHASFMVWKDEAFEIWTRGWGCMFPEGDSSRELLEKVQKTYYLVSLVDND
YVQGDLFAAFKI
>A0A2R7UHE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas plecoglossicida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7S1Y800|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grammatophora oceanica|TrEMBL
QSALDGGITNIVALRGDPPHGEEEWKASSVDFTCALDLVKFIRAEFGQENFGIAVAGYPE
GHPNAISQIDDPSTLTDSEKARSSCFDGITYTCKDEDYKKEMAYLKEKIDAGGDLIITQM
FFDVDVFLQFVDDCRAFGITCPIVPGLMCINAYGGFTKMTKFCKTRVPEFLSTKLQSIKD
DPTAIKEYGMEFGAQVCQKLVDSGKVEALHFYTLNLEKVVYGILDKLYGSDLLGMTQESD
AKSMVAVGSAWARVGDSVKTVQHGNGTVLEVLADGAAKIKIESWEGTREDPTVVVQKGDY
EKVF
>N8WFA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 758|TrEMBL
MSLFSQCLEQKRFCILVEYLCSKRDTLAVTQSLAGFPAMMTLTDRVHSDEDPAPLELAQR
YSSEIEKLLHFSGKGRDIKEFEHFLDQAEQQGYHNLLLLTGDKLKNHNFGREIPAQRSRY
LESVSAVMAAKQRNVFNIGVAFNPFKYTEAERDAQYLKLHKKIKAGADFLITQLGFDLDC
LQHSQSFISQNYKQFPLIACVMPLTLKRAQFMVKNQIAGLVIAPHIVDVLEREYAVDPVQ
AEANVYARCALQILICKHLGYVGVHLSACHKPQEQQKLEQFLKQFENWSLEACEKAWKDL
WKMDSGLELKPELSTFSKPVSQMQILKYKKMHLMHHIFFASQAALGVGRFIFKANFWNKP
RPQHLLLKMEHWSKQQLVGCESCGHCRLDDTLYICPETCPKGLANGPCGGTTLDQCEFGD
RECIHSVKARLAKSVDQTEVLRSKLIPAISIETRYTSSWKNWFRNSDLN
>A0A6N7HEI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola sp|TrEMBL
MTSVVARIPGDRPVFSVEFMPPRDDADEQRLWNSIRSLEGLDPAFVSVTYGAGGSSRDRT
IRTTGRVVRETTLVSMAHLTAVDHSVAELRNVIGWYAELGVRNVLALRGDPPGDPMGEWV
RHPEGLAYAEELVRLVRELGDFCVGVSAFPYGHPRSADVDTDTEYLVRKLRAGADFAIAQ
LFFEADDFLRMRDRVAARGCDTLLLPGIMPLTTPKILTKTVELSGAQVPASLTERLGPLA
EDPKAFRAAGMDVTAELSERLLAEGVPCLHFYTFNRSKATKEMVDRLGLVPSRPDTQANL
RPVG
>Q92P13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium meliloti (strain 1021)|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHERCYILVGVG
PMASAKTARWIRSNVPGIHIPDSIIKRLEGAQDQKKEGKQLCIDIMNEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLRGRKPWTREAAPTDALVAERLEHIREGKEENQQQMAEAAAH
HPH
>A0A1X7PF15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium australicum|TrEMBL
MTPILPLQPDENPAGVHLPLEPLPGHTSRGRLERILRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSSSLLETIRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPYDFRPIHLGKKIAAGAQFIQTQYCFDVPMMKTFMAKARDLGLLDKVF
LLVGVGPLASAKTAKWIRSNVPGIHIPDTVIQRLEGAQDQKKEGKQLCIDIINEVKEIPG
VSGIHVMAYRQEEYVAEIVSESGVLRGRRPWNREAARDELVVAERMRHLREDAPDQAPQK
IVERVGH
>A0A3R8QFD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium aquaticum|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLRDIAQDYWQSGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTSMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPNVAR
>A0A1B8C4I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. WSF 3629|TrEMBL
MADSPTTDKITDKIAALPQDASYFSLEFFPPKTAMGSTNLRARLDRMARALRPLFVTVTW
GAGGSTASRSMQLAELCQRDLGLTTCLHLTCTNMSRALVDDALKAAKEAGIQNILALRGD
EPRGEYKDALEEGKEGEDEFVWAIDLVKYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
EHDLPYLVDKVQAGADFIMTQLFYDVDAYDKFEKVLRDHSSGAFKTIPIIPGLMPIQSYQ
ILRRTTKLSNAKLPESIIDRLDAVRTDDEMVKKVGVDILAEIVESVKATKQRTKGPKGFH
FYTLNLEKAVAFILERVNLIPSFTPVLTSDVFAVDDITDTIPLPQLLINGEKKNRRQSSV
GSGPHNFVIIDRDEASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNQPTSRPDITSIFVQYLNGTLSALPWSDE
PIAAEANLIKDELVKLNQKGWWTIASQPAVNGARSQDEVVGWGPKGGWVFQKAFVELFVP
TSDWTRLKPLLEGNAEVSFLAQSASGEFLKSKLDLGPGEEGTETNAVTWGVFPGKEIVSP
TIVEEVSFRAWAEEAWQMWGEWAAVFGKSGEESRRFLDGVAKDGWLVNVIWHDFVGMCKA
KEGRSDEEGYKGLWDVLIEA
>A0A2D7AEG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneola sp|TrEMBL
MKVTQYFENAGDSTLFSFEVLPPLKGQHIQTLFDHIDPLMEFNPPFIDVTYHREEFEYKK
LPNGLMERKTVRKRPGTVGICAALQNKYKIDAVPHIICGGFTKEETENALIDLNFLGIDN
IMVLQGDARKPDRDFXPEXGGHAYASELLEQVVELNRGIFLDDELEQAHHSDFCIGVSGY
PEKHMAAPNLELDMKYLKQKVDKGADYIVTQMFFDTQKYIDFVTKCREMDINIPIVPGLK
PITSLRQLTILPQIFHIDLPYDLSNALEKAKNNDQAKEIGIEWAIQQSKELIEFGVPTLH
YYSMGKSESVYKVAREVF
>A0A3F3I123|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneola sp|TrEMBL
MKITEYIKQAKGKALFSFEVLPPLKGQNIQTLFDHIDPLMEFKPPFIDVTYHREEYIYKK
RENGLLERKTVRKRPGTVGMCAAIQNHYKVDAVPHIICGGFTKEETENALIDLNFLGIDN
VLVLQGDVRKPDRQFIPEPDGHSYASELLAQVVDLNKGIYLDGEIENAMPSDFCIGVAGY
PEKHETAPNMESDLRYLKKKVDGGADYIVTQMFFDNQKYFDFVNRCREKGITIPIIPGIK
PVTTLKQITLLPQLFNIDLPEALTQELEKCTNNEAAREVGREWTIQQTKELVEFGVPSVH
FYSMGKSTSVYEVAKEIF
>A0A520P573|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MQQPQISFEFFPPHTIEASFKLKDTIQILAPFSPRFVSVTYGAGGTTRELTHQAIKALRG
STDLNVAAHLTCVNVSRKRTLQIADQFAADGVTELVALRGDPPKGSSAFKPHHDGFKNTC
ELIQALAETEKFFIRVGAYPHKHPEASSSEKDILWLKRKFDAGAKEAITQFFFEADDFFR
FRDACVKAGIQAPIIPGILPIENWAGTRKFAQKCHANIPVWLDDAFTKAERDGRNDLLAT
AVCSELCSDLIEGGVDAMHFYTLNRPELTRDICFSLGIFPAATLENVA
>J6HPM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella sp. OBRC7|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELCTIAKDYWDSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFRQAKKFADMTNVRIPTWMAKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>W7VMG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. M42|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTQAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWIAHPEGVRYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVDSDTAYFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAATGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFERVADDPEAVRRLGVEQASEMCEKLLDEGVPGIHFITLNRSPATREVWQRLR
AAARV
>A0A2A4NDN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MSATAPAVSFEFFPPQNLEGSFRLWDTVQTLAPLDPRFVSVTYGAGGTTRDLTRDAVATL
HKSSGLNVAAHLTCVDATREETLGIARGFAEAGVRDIVALRGDPPKGSNGFEPHPQGFAS
SIELISALKEVGDFNIRVGAYPDTHPEAANAQADVDWLKAKLDAGATEALTQFFFEADTF
FRFRDACDKAGIDPSLITPGILPIESWKGTRNFARRCGATIPQWVDDAFEKALRDNRQDL
LATAICAELCSDLIDGGVDKLHFYTMNRPELTRDVCHALGVTPKTQLQNVA
>A0A2A4Y9W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodospiraceae bacterium|TrEMBL
MLANKIKNRESGIVLYGIVPPKKGTDAEKVKEIAALQVQRLQSLKLDGLILYDIQDEKSR
TAEARPFPFLETLDSFSYSQDHLSALAIPKIIYRSVGKYSPSELSEFISNAAQKDDLTVF
VGASSKSQTVSMSVSEAYTLKKQINSDMLLGGVTIPERHQTKKDEHIRVFNKIAQGCSFF
VSQGVYDINASKNFLSDYYYYGKEHNIPLVPIIFTLTPCGSLKTLQFMKWLGISIPPWLE
NELTHSNDIIQQSVNFSAQNWQELKAFANEKNIPIGCNIESVAVRKVEVEAAIELLQRVS
TL
>C2UJ27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus Rock1-15|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2U3K9L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacter sp. SbD1|TrEMBL
MSDKSVMKSGSNLERVLTSGHFAVTCECGPPKGADVEHLQKKIELIRGCVDAANVTDNQT
AVVRMSSIAAGAIMVRSGVEPVMQMVTRDRNRIAAQSDIFGAYALGIRNMLCLTGDHQIF
GNHPMAKNVFDLDSIQLLDVVRTIRDKGTVNCGDPVEGGIRMFLGAAANPFADPFEFRVI
RLAKKIRAGADFIQTQCIYDMGRFREFMKMACDMGLDGQCYILAGLTPLKSAGMAAYMNK
NVSGISVPDEIINRIRGVPKGNQAEEGINILLEQIGQVREIRGVAGVHIMAIEWEERIRE
ITERAGFLPRP
>A0A3A8JC26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus terminator|TrEMBL
MKIRNCLNPSQPCFSFEFFPPKTDAGVASLLRTVEELAPLNPGFVSVTYGAGGSTRDRTV
DLVTHIKKHTGIEAMAHLTCVGHDRDELRDVLRRLDAARIENLLLLRGDPPQGQQTYEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVSALRARS
>A0A100HT14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia sp. NT80|TrEMBL
MNDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILNTYRENGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGDAFHIEVAAYPEYHPQARSPKHDLDNFARKVKAGANSAITQYFFNADAYFQFVA
DAHKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWVAKRLESFGDDRESIRAFGLDV
VTALCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A101R020|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces longwoodensis|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTFSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPQGLTYAAELVELIKASGDFCVGVAAFPAMHPRSADRDVDVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVAAAGCDTPIIPEVMPIASVRTLERIPSLTNAAF
PAALKERILTAKDDPSAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHPPQA
>A0A2M7P887|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_10_14_3_um_filter_60_8|TrEMBL
KLSFSFEFFPPKEEAQWEKLFQAIADLMPLKPSYVSVTYGAGGSTRDRTHNLVVRIQQET
DITVVSHLTCVGSSREEMLAILRKYDASGVHNILALRGDPPRGVTNFQQPADGFGHAAEL
VAFIKQHFPHFCVGVAGFPEGHPETPNRLREIDHLKAKVEAGADFIVSQLFFDNRDFHDF
RARCELADIKAPIIAGIMPITSRNGMMRMADLAAGARVPARLLRAIERAGSDELIQKVGV
HWATEQVRDLIDHGVRGIHFYTLNNSRETLKIYEALGVRDSRQLSA
>A0A061LYB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter sp. UCD-THU|TrEMBL
MSPLPLAGSAPTRARFSFEVFPARSGAAALALGHAVQHLSAAGPDFISVTYGANGSNRDA
SLDLLKYLRDHTDALPLAHLTTVGESRDAVRETIHRIMDAGVHDFLALRGDPPRGLDEHD
PAVTGSLSSLELVDLVAEARAERPPLTSVGRTAVAAYPNGHPLSRSRSQDIEWLIEKQEA
GAQFAVTQLFFRAEEYLGFVGDAQSAGLRIPVLPGLMPVSTSAQLRKVASLAGRPAPEGL
ERALEEAGGYAPELGVEHTVDLARALLAGGAPSVHLYTFNRHEQVLAVLRELQLLTPDPI
G
>A0A355VDR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia sp|TrEMBL
YARAGVRAVLALRGDPPRGAEDYNRDADAFRHAADLVAFIRGYNESGRHPDPEGFAIGVA
GFPEGHPATPNRLREMDFLKAKVDAGADYICTQLFFDNHSFLDYRERCLLAGIKVPILAG
IMPVTSLSGMNRMAELSGGTCFPARLLKALKRAGSNPDAIQEVGIQYASSQCAELLDSDV
DGIHFYTLNQSRATREIYRNLGLKDSLQLLEHGEDK
>A0A0C2I2W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas batumici|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLADYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLELYKNAGIQRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGADSAITQYFFNADSYFY
FVERVRQLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQAFG
EQVISQMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1K1WP92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinospirillum alkaliphilum DSM 21637|TrEMBL
MSSAPVSFEFFPPKTPAGQEKLLAVRDQLAATNPDFFSVTYGAGGSTQDGTLKTVLALRA
TGIDTAPHLSCIGASRDELRELLRDYRAQGIGRLVALRGDLPSGMGMGGELRYANELVEF
IRSEFGSDFIIEVAAYPEAHPQAAGLEADLKNFIRKCQAGADSAITQYFFNADAYFHFVE
RVRAAGVEIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLESYGDDSDSICRFGEEV
IVRLCQQLLDGGAPGLHFYTLNQAEPSLAILHQLGK
>A0A6A5K4J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Decorospora gaudefroyi|TrEMBL
MMEKITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGS
TATKSLELAEICQRQLGLTTCLHLTCTNMDRSLIDDALEQAKVLGIRNILALRGDAPRSD
EYRDEGTPPEQDSNKDFTWAIDLVRYIRKEYGDYFCIGVAAYPEGHSDQSHPQHQDPQSD
LPSLIEKTKAGADFIMTQLFYDIEAYDKFEKMLRAHESGVFKTIPIIPGLMPIQSYKILL
RTTKLSHARLPTDMLTRLDAVKSDDELVKQVGVKIMDEMVEHIKARPDTCRRGFHFYTLN
LEKAVSHILEDTRLIPPMTTDDDEVIVETTPAINLEPPPNGTIPHRRRSSAVNSGPWNRV
IISHPSATKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWG
DARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKDDISTLFRRHIEGDLEAIPWSEQGLS
PETSIISKQLLALNAKGWWTVASQPAVNGVKSTDAVFGWGPKNGYVFQKPFVEFFLPAAQ
FALLKPKLEAHDQVTFFAGNAAGEFEASQDDGVNPVTWGTFAGKEIVTPTIIEAVSFRSW
MEEAFSIWKEWQRIYAPRSRTSRLLGELREDVWLVNVIWADFVRGEGLWEFLAE
>A0A010SLG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens HK44|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLANFVRKANAGASSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A0F8ES73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. 2.H.T.1A.3|TrEMBL
MLFNFREKLNSRKFLVTVEVSPPKGTMFSAPLEDACQLKGVADALNVTDNQCSIMHMSSL
AFSKLLLDQGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDHPACGDHPGSKP
VYDLDSVQLIELVRKLDSGIDFAGKRLDGGTSFCAGAVSGIDPENTLQLIKLEKKVRCGA
DFIQTQAVYDVGMFEEFMEAVNHLEVPVIAGLIPLKSLSMAEYMNKNISGIHVPEEIRLR
MKDASSPIEEGLSIASDTIKELTKLSRGVHIMPIGSHKNTPRLLSMAGISGK
>A0A7C7JLP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacterales bacterium|TrEMBL
MFENFVKKLFEGRYITLETTPTYSANINNLIEKLENSGVVSYIDGFTTTDNPLAKLKYSS
LFGAVKIQERFQKPVIATLSMRDRNKIALQSDLMGANDFGIQAILALTGDSAKASDQPNS
KGVFEGDSTLLLDIINCFNRGINYAGKPFPKDEEPKHIYPFAVINSYSKNPKTLLKKMIK
KIEHHSIGIITQPIYSLQQAEQLLELFEKAKKECNCDNPQTQLVFGFFPLTKFRTAQFLS
AHVPGIYVPNEWLDRLQNGEEEKIGMEMSKTLFEQLMELHPKIHIMTANKFDIANQILSD
R
>A0A8B7MNN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila elegans|TrEMBL
MHAIQESAGGPSYTSYIPCVTFAPGQNASTMEEQRIGPLVAQRTAQRRIFYGIEVTASEP
GGKPTCLDFNQFLPLLPTFVSVVWLGQRYWDVEPVGQVESLQLAKHLATHIPVLPHLSAY
RLQRKRLDQFLALNFSSLLAVRGDQVHEGQEFRIAQPMVEQSRRQRGERISICVPGYPEG
YTSLGDVPPDSARNIKFLKAKVAAGADCIITQICYRPEAIVQFVRDCRAAGITVPIVVGL
MTHETFRTYSTIERIVGVHLPNELREELNQLRSHHNSTTKSEPNRISRYFVSLTVRIIRH
ILDANVGIWGFHFFTLNHFKPVKAVLQELRELDLL
>A0A7V3M390|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division NC10 bacterium|TrEMBL
MAGVLEALRDSVLVCDGAMGSMLYQTLGHLRCTDEVNFTHPESILKIHLEYIAAGAQIIE
TNTFGANRLKLAAYGLADRTVEINQRAVKLAREAREIAGREVFIAGSIGPVGTLNETLEE
PTRTALTEAYQEQARALEDRGADLLMVETFPSLAELLCCLGALRGATRLPVVAQLTFTEE
AKTPTGVSPRAAAEALRPLGLAAFGLNCSVGPGDTLGILREMAAAADGHPLSAQPNAGFP
SRVAGRIVYPASSPEYFANFAQEAVRLGARIVGGCCGTAPAHIRAMAEAVRYLSPGRAVS
ILPRPEAVEEVQAPAPELSPFGRKLKAGTFVRLVELDPPKGIVLDRVLEAAKGLKDAGCV
DAVDINSGTLARIQLDSLMMGVAIERRVGIETVPHLTTRDMSVMGLQSALMGAWAVGGIR
NILAITGDPPALGDYPQARGVFEIDSIGLVRLIQRLNQGLDFAGKVIGPPTAFTVGVALN
PTAQDLETELKRFEQKVAAGAHFAMTQPLFAPELWTDFLRRLGRPPIPILVGVWPLASYK
QALRLHNEVPGIVVPDRIQDLMKQAGPEARAEGLRIAREVYAVVRETAAGVYVIPPFHRY
DEALAVLASGGL
>A0A1I1GDX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructobacillus durionis|TrEMBL
MIQKISDTYLDNTQVVLSNELTKKGVGTILENGFSASQEKYDFFSLVNQGDSQAEFDELL
ILAKEFQERTKRPILVHLRLGDVTPYTLLDFIEKTRKLGLQNFLVLSGDKRVNEQGFYTV
EDLLRALRKELGGRVTLAATVNPADPTAVEKVESRQSAGADFLISQISFDSQPLMDLKKE
LEQDGLKVQLVAGMLNQPTIGQIQWVEKTFGLRVPLAYKENPKKVNRTVEKSLQIAGFSA
FHFFTLPNF
>A0A220UFP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium avium|TrEMBL
MTESPHPGPVSHAAAQGREVQFEVIPLRGIIDEVSTHLPPGARVTVTASPALGLPATLET
AGELAQRGFRAIPHLAARMLHGAGEVEEVLARLSEKGVHEVFVIAGDAPHPAGGLPGALE
LLEAIGASGSGITVGVGVHPEGHPFVSESEAMRLLRAKAEHASYAVTQMCFEAAPLLAWV
RRLREGGISLPVRPGIAVPAGTARLLRIGTRIGVGRSLRMLSGEDAGVRRLLGPGHWAPG
PLLEELERARAAQPELGLHGPHLYTFNAVRVARECAEGL
>A0A516NIN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia otitidiscaviarum|TrEMBL
MSFDDVRGASTPGRVSRTLQVSGTPSVVQHLGPRPDGSIPFSVEFNPPRDAAGEARLWRA
AREFERLHPAFVSMTYGAGGSTRDRTIRVTGQLARETTLLTVAHLTAVDHSVAELRSIVG
AYADCGIRNLLVLRGDPPGDPLGEWVKHPDGVEYAEELVRMVRELGDFHVGVASFPQGHP
RSVDLDSDTRFLLAKLRAGAEYSITQMFFDVEHYLRLRDRAVAADPEQGAKPIIPELMPI
TSLRTVQRAEELSGRPLPAAVMERLRKAAGDGPEENREAVRAAGIEIATEMAQRLIDEGA
PCLHFITLNFAKATGEVLSNLGYTVTPAPVRA
>A0A4V2IVH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquirufa antheringensis|TrEMBL
MTKITKYFEEAAGKTLFSIEIIPPMKGQHLGELMSHIEPLMEFKPPFIEVTYHREEYVDK
VVDGVSKRIPIRKRPGTLGICASIMQRFQIEAVPHVICGGFTKEETEDFLIDLHYLGIEN
ALLLRGDQEKGEAHFIPKPGGHAYANELVEQVAAMNQGILLHEETESLPTNFCIGVAGYP
EKHIDAVSFDQDLRYLKQKVDAGADYIVTQMFFDNAKYFDFVKKCREMGIIVPIIPGLKP
LATERQLDILPEIFHLEIPTEFVSEARKCANNAAIKQLGIEWAVQQGKELIQAGVPALHF
YTMSKSDSVRAIAEKLF
>A0A257GYG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium PBB4|TrEMBL
MQSKVRTPISLEFFPPKTAEGADKLRVVRQQLYGLSPEFCSVTFGAGGSTQEGTFSTVRD
ILQEGVSAASHFSCVGATRATVRAQLASLKAMGVRRLVALRGDLPSGYGAGGEFQYASDL
VQFIRAETGDDFHIEVAAYPEVHPQAKSSSSDLQAFATKVRAGANSAITQYFYNSDAYFK
FLEDVQGLGVDVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQGFGDDIASIKSFG
LDVVTDLCEQLRAGGAPGLHFYTMNQSAATLTLCERLGLTA
>A0A1H4ZQ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium erythrophlei|TrEMBL
MTETISSLPNGQRAPKTPKISFEFFPPKTEEMERSLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTISRILRETDLLPAAHLTCVSASRGEIDEIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAAIKKRHADIEISVSAYPEKHPEAADFDADIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPTGA
QKAA
>A0A564T4U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ruminococcus] torques|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPE
AMKQAGIAYATDQIIDLLANGVNNIHIYSMNKPEIAIAIMNNLSEITKC
>A0A2U1ZWY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serinibacter arcticus|TrEMBL
MTTSDLYRPPRPTISYELYPPRTPKGETQVWDTVTQLADHVADYFSVTYGASGSTASTSQ
ALVERIINETSVPVIAHLTCVGRTAEQLREVVGAFLDAGVRNFLALRGDPPEGVVDWKPA
PGEVGRACDLVTLIREVEAERFGSRGLDPISRLADHRSRRTAVSIAVAAYPGLERAGAAP
DGGHPAGGVTDGAVAGASRFRVREDELVALRAKQDAGADFAITQLFFDAAAYRELLGASR
AAGIRLPLVPGILPLTDPARIRRLCDLNGIAHPAEILGTLDATTDPEERRRIGLEATTSL
VRDVLAAGAPGLHLYTFNKADGVTALLEDVLAERMPA
>N9M966|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 53.82|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDKDIQHFVEKVNAGANAALTQFFFNPDAYFYFV
ERIQQAGVNIPVAPGIMPITNASNLIRFADSTGAEIL
>A0A410UL73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella sp. M7H15-1|TrEMBL
MLAISFEFFPPKTDEQRAQLDRVAKELKGLKPEYVSVTFGAGGSTLSYTGDTVARLHQQH
GLEVAPHLSCVGGTRQEIADLLDTYRAAGYRRIVALRGDLPSGMATPGDFRYAVELVRFI
RQHTGNHFHIEVAAYPEMHPQAEDVQADLRHFKTKIEAGADGAITQYFFNADAYFRFVDD
VRRLGVSVPVVPGIMPISNYAQLKRFSDACGAEIPRWIAKRMQAYYDDVASIRAMGADVV
AQLCRRLLEGGAPGLHFYTLNRAKATRAVLDQLNGMH
>A0A1F2TYE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium RIFCSPLOWO2_02_FULL_65_29|TrEMBL
MPLKPFLETLDERVLVCDGAMGTMLYSKGVLINKSYDALNVSQPELVVDVHQEYVRAGAD
IIETNTFGANRVKLGSFGLADSLREINAAGARLARSAAGDRAYVAGAIGPLGIRIEPWGK
TGVDEARAFFREQADALAEAGVDLFVLETFRDLNEMGAAIDAVRNVSALPIVAQMTTEED
GNTLDGTPPEKFAPELERRGATVIGVNCAVGPGPMLETIERMEAVTSRPLSAQPNAGKPG
DVEGRNIYLCTPEYMASYARRFILHNVRIVGGCCGTTPEHIRQIKASVRGLQPGAAAPAA
RGPAGRRAAVIAAPPVPREKKSRLAAELTRGAFVIAVELLPPRGFEAEPAIARARELRRY
GVDVVTIPDGQRAGARLSALALAVLIEQQAGLETLLYYSCRDRNLLGIQSDLLGAHAMGL
RNLLLITGDPGRVGDYPDATAVFDVDSIGLTNVVSRLNHGADVGGQPIGAPTAFHIGVSV
NPAASNLDEELRRFEYKVEAGAEFVLTRPVFDLQSFERFLKRLEPARLPVVAGVLPFESV
KNAEFMANEVPGVRVPETLVARMRGADALDAAAAEGMAIAREIASALRTMVQGVQVSTSS
GNVDAALAVVDGLR
>A0A7T8V9T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium animalis|TrEMBL
MHTPMFSLEVFPPKRTSPVGTIYDTLDGLNDMKHDFISVTYGTGKSADRTATARIAHTIR
SEYGIDAVAHLTAQYLTARDVDEALAMFDEAKVSGVLALRGDRNSEREPAGVFTHASDLV
CYIRERRPNLKIYGACYPEKHPQAATLDEDVANLKAKVDAGASHLISQLFYDDDDFIAFL
GKARAAGIDVPIEAGIMPVTNAKSVRRMTNMCSSWVPRKLERMLEKWGDDPRTLREAGII
YASEQISDLVAQGVDGVHLYTMNHPSVSRRIWQNVGNLFEKA
>A0A6N0HRK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Reidiella endopervernicosa|TrEMBL
MKSQQNHPKQFSFEFFPPKTDKGAENLRQVRDELATLNPKYASVTFGAGGSTHAGTVETV
REMMAAGLDTAPHLSCIGSSEEDIRALLNGYIEMGVKRIVALRGDLPSGMGMGGAGAFNH
ANELVEFIRSETGDHFHIEVAAYPEFHPQATSASADLDNFAHKVKAGANAAITQYFYNLD
AYLHFVDECEKREITIPIVPGIMPITNIKQLARFSEMCGADIPRWLRLRLESYGDDMESL
RAYGLEITAELCRRLLEAGAPGLHFYSMNRVEPVKTIWQQLDLSND
>W6MQN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kuraishia capsulata CBS 1993|TrEMBL
MATIVEKYRQLPEDAAFFSLEFFPPKTETGLRNLMARLGRMSALNPMFVTVTWGAGGSTQ
SKTLELAATCQKELGLTTCLHLTCTNTDREKIDHALKTAKDNGIKNILALRGDPPRGEDL
GSGSGEFRYAVDLVRYIRKHYGDYFCIGVAGYPEGHVEGSDDSEQSVEHDFPYLVEKLNA
GADFLVTQLFFDVDKFLEYEKKVKSCKEIKNAKDLLILPGLMPINGYQLFNRAAKLSHAS
VPKEIQDRFPDSIQGDDNKVKEVGVQVLIEMIDKIYGNSDKKIRGFHFYTLNLEKSIAEI
IDRSPVLSKILENDDVENAIDEDVDADDTEAKRSRFIQNLESRSNSNKVISDESQPLAIT
TSDLKSSSIGTKPSKRTILAISLGKGTLGKDATWDEFPNGRFGDSRSPAYGEIDGYGPSL
KLTSSEAYESWGYPTTVKDLSKLFINYLLSKLKVLPWSELGLNSETAIIQEELINLNKKG
YLTISSQPATNGSNSTDKIFGWGPDNGYVYQKSFVEMFVPKSEWESVLKDKLAKDENVGY
YKSDLEGAFETNLPESSAMCVTWGVFPDREVVQTTLLGEESFKAWNEESFKIWKEWQRLY
PNRSKSSDVIQYVLDNYCLVTVIHHDFQKESALWDLLLD
>A0A1L9CG06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium pusense|TrEMBL
MIIKRIMHTLPDISATSVIPASIEASPAQVLGPASLAGLFPQGVRVYLTDTGAASQVKLV
DAAKHLRDLGYEPVPHLAARRIASRIDFEEQVKRLAGDAGVTDVLAVGGGVEKPEGPFTS
TIDMLSTGIFDRCGIRHIAIAGHPEGSPDFNDETATAALRLKRDFGERTDAAMRIVTQFG
FDSARFIAWAEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LARGHSPESIVGPIERHWRDNPQGPIRQIHVFPFGGLQASSDWLVSRGSWRTENADHAAA
TGSVAI
>A0A368N4Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallincola holothuriorum|TrEMBL
MALSHAQQIGLLNQSLSELGKINVSFEFFPPSNEKMEQTLWNSIERLAPLKPKFVSVTYG
ACSGERDRTHDIVKRIKKDTGLTAAPHLTCIDASRDELRQIARDYWQNGIREIVALRGDL
PEGSNERPDMYAADLVALLKSEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFNQLKRFAGMTSVHLPQWLHKMYD
GLDDDAMTRNLLGASIAMDMVKVLAKEGVKDFHFYTLNRADLSYAICHSLGVRPSN
>A0A542VA82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SLBN-26|TrEMBL
MSQDRRYSFEFFPAKTEAGHEKLLATARTFAGYKPDFFSCTYGAGGSTRDRTLQTVLQLD
GEIQVPTAPHLSCVGDSKAELRALLAHYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VEFIRAETGDHFHIEVAAYPEVHPQARNFEEDLKHFVNKVKAGADSAITQYFFNADSYFY
FVDRVRQQGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYADDTASIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A4V5TYQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. 15WGF|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAARKPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRDETGDHFDIAVAAYPESHPQAPSLDKDVENFARKMNAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAISAF
GTDVVTRLCERLLDGGAPGLHFYTLNQSAPALKVVDNLS
>F7MAS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. 1_1_30|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A378Q5T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella atlantae|TrEMBL
MMTPFSIEFFPPKTDDAATKLLHTFAELNALQPEYFSVTYGAGGSTRARTLGIVKTLSEA
SATPIAPHLSCIGDGKAEIAELLDTYAALGISKIVALRGDLPSGQVGFGELPYAVNLVQF
IREYAGDRFEIEVAAYPEMHPQARNFASDIDNLVAKYRAGASAAITQFFYNPDSYLYLRD
ALAKRGVQPEDFALKAGIMPITNASNLIRFADACGADIPRYIRRQLADFGDDRAAIRAFG
FDVVMRLCERLITEGVPALHFYSMNQVNPTKALIEALDLRQAVDPTSNQTTKSIKV
>L1KUJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces ipomoeae 91-03|TrEMBL
MGAAGLRALLHSVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLTARLAGH
GYRVVPHVPARLLRDDAHLKEVVVRLAESGVEDVFVPAGDADPPAGAYDGALPVLRRLTE
LGSPFTRVGVTGYPESHPLIHDDITVQAMWDKREHATYIVSNLCFDPRVLGEWIARVRHR
DITLPVHVGVAGPVQRAKLLSMATKIGVGESTRFLTRHASWFLRFAAPGGYSPHKLLTRA
ESALTAPSAGVAGLHLFTFNRIAETERWRRALLDRLEG
>A0A5J4RIX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
MKVADLIYNSKQTAFSFEILPPLKGNGIEKLYHTIDILKEFTPQYINITTHRSEYVYTDL
GNGLFQRNRLRRRPGTVAIAAAIQNKYNITVVPHILCSGFTKEETEYLLIDLQFLGIMNV
LVLRGDKAKHESVFTPEENGYTHAIELQEQINIFNKGIFIDNSKAQEISVPFSYGVACYP
EKHEESPNMDTDIYWLKKKVEAGAEYAVTQLFYDNRKYFDFVEKARQAGIHIPIIPGIKP
FKSLSQLTMIPKTFKVDLPEELSHEIRKCKNDNETCRVGIEWCTLQCKELIAHKVPSIHF
YSIAAADSIKEVAKKIY
>A0A850SLJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvularculaceae bacterium|TrEMBL
MTTEISFEFFPPQSAEGLDKLRAVRARLAELHPTFFSVTYGAGGSTRERTCDIVMEIAAE
GHAAAPHLSCIGSTRTGIREILHGYRDHGIRRIVALRGDLPSGMADAGEFRYANELVEFI
RQETGDTFRIEVAAYPEWHPQAKSPRADLLNFKRKVDAGADSAITQFFYNADAYAHFVEE
ARSLGIDIPIVPGIMPIGSFSKLARFADSSGAEIPRWMRRKFESFGDDADSIRAFGLDVV
TELCERLLALGAPGLHFYTLNQATLSTEIVRRLKLAS
>A0A5C9T494|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cholerae|TrEMBL
MGYTHAGHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQNIVALRGDI
PAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDVESYLRFRDRCVAAGIEVEIVPGILPVSNFKQASRFAAQNNVKVPNWMVKQFEG
LEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A847SJ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga eiseniae|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPAFINVTYHRSEHMFKKK
ADGSFEKVEIRKRPGTVGICAAIMNHYTVDAVPHLICGGFSREETENALIDLNFLGIDNV
LVLRGDAPKNETFFEPDPHGHSYAIELLDQVAHMNNGVYLEDDLQGGVKTNFCIGVAGYP
EKHFEAPNMQTDLAHLKRKVENGADYIVTQMFFDNQKFFDFVTKCREMGITVPIIPGLKP
LTSRKQMTMLPRIFHVDIPADLSTEILKCKTDKDVELVGTEWLIAQSKELKAFGVPVLHY
YTLGKPKVIQKAVAAIM
>A0A059DCQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eucalyptus grandis|TrEMBL
MKAIEKIREALDGRGDEGEPVFSFEFFTPRKKADVNALLDLIGRLVVHGPAFCDLTWRTG
SLATDDITLDMVGKMQNAVGVETMMHLTCTNMPVQRIDRALDRIKSDGIRNVLALRGDPP
TGQLKFVPVPDGYGSGLDLVKHIRDKYGDYFGITVAGYPEGHPDVIGSNGVASDEDYKNE
LAYLKRKVDAGADLIITQLFFDTDIFLKFVNDCRQVGITCPIVPGIMPIATYKGFARMTS
ICRTKIPAEVSAALEPIKDNDEAVRNYGIHLGTEMCKKILASGIKTLHIYTFNKEASAVA
VLMVVPNTL
>Q64CC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon GZfos23H9|TrEMBL
MGDEVYSDLMRELKEGKYVFTGELEPEKAGDVNEPIEMARELVGMVVACNVTDNPQSFAY
VNSMAASYLIQKETGMECVYQLRCSDRNRMALLSDVLGAGALGLKNILALAGDHVSLGDT
PDAKPVFDLDSTTLIKLIRTMVDEGKDLGGNEIHNPPKLHVGGAAAPGAAHLKAEVGKVK
RKINAGVEYLQTQVVYYTDVLDKFFDELGKVDVPILVGIFPARTFGQADFFDKYVAGVDV
PPDYLEAMRATKAIKDKDKKKEEVDRVNIEFFTGFLEHLKGTPAAGCHMMAVGYPRIIPP
LKKLME
>A0A6N2U2W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia glucerasea|TrEMBL
MKITEAFERGEFAVTAEVGPPKGIHIEGLLEEAKTYLSDITAVNVTDNQSSVMRLGSLGV
CKALKDEGLTPIFQLTCRDRNRIALQSDLLSAAMLGIENLLLLTGDHTKMGDHPQAKPVF
DLDSVSLIHAVRQLEEGVDLGGNALVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVRAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQIGIIIPKSVGMARFMNANVAGVHVPEDMINE
LKADKEKTKAGITGVEIAARIIRECKPYCQGVHIMALGWESKVPEVLKLAGI
>A0A847SVG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga eiseniae|TrEMBL
MLKEKLHRPGSNLVFYSLTPPKATTQPEQVKIIAGKQIERLQGLPIDGLLLYDIQDESTR
TEKERTFAFQSTITPEEYSKNYLAPLQVPKVIYKSIGNLDKEQFINWLQANQHIGYAVFV
GASSHQQVEATNFSLQDAYDLRNQYAKSLVLGGVTIPERHTKKGDEHLRIFNKINKGCSF
FVSQCVYSLNDTKDLLSDYYYAGLDNDKSLSPLIFTLAPCGSLKTLQFMEWLGIEVPKWL
YNDLKHSKDILSSSIETCKNIAIEILNYTQAKNIPIGFNIESISIKKEEIEAANELLKDV
LQLTKGAGIPAENRLIPA
>A0A6V8NU45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hakubanella thermoalkaliphilus|TrEMBL
ARYMKNKVAGMDVPGEIVERLQAASDPKAEGIKLCLDIIEQVRAIEGVAGIHIMAIEWES
AVPEIAERAGLLPRPQID
>A0A242YDQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar novosibirsk|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A4V2LJC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4641|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRAVHQDLQQLNPEFFSITYGAGGSTRERTLAAISDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDLDIQRFAEKVHAGANSAITQFFFNPDAYFYFI
ERIAKLGVHIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSKSIQAFGHE
VVVKLCERLIAGGAPSLHFYTMNHIQPNRQLVTDLGLA
>A0A4R5BBC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura rubrisoli|TrEMBL
MRRLRPDRPPTVRELLASGGRSFSFEFFPPKTDKGARTLWRTIRQLESLHPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVDHSQAELRQLIGRFASVGVRNILAVRGDPP
GDPTGEWIKHPDGVEYAADLVRMIRSYGDFSVGVAAFPYKHPRSPDVETDTRHFVAKCRA
GADYAITQMFFRSDDFLRLRDRVDAAGCDVPIIPGIMPVTQISTIDRSEQLSGAPFPPEV
RARFEAVADDPEAVRRLGVQHAAELCQELLDQGVPGIHFITFNQSTATREVYGLLEAGGY
GAKGSVPPMTA
>A0A1I8FQK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
LTQTQQPARSHEQTRIPLTQVDAGGEFIITQLFFESADFLRFVSDCRGSAIDCPIIPGVL
PSLRAHRQAVQADGPGQHAARNRADRDNDEAIRNYGIAQCTQHVPGASAEAARCTRLTQA
YQRLTQSLSELDIKAYQSLTQAYQEVDSRLIKGIHFYTLNRDAATIPHFEEHRALARGSA
SAVAHGNRPPITSAAPRPCDRVLVPAAHQLLRAPDAGTGMTIPTAGGAPSVPRLASSGLL
FVLPDCRAVRASKAGAAPHVGQRADQRAATGHLAECSPATCPGNQSARTVSRVTRLPWGD
EEPLGRLRRSPARRRRRGQRLAGLSERGLLATNHLLRVNGASSDHPVHGWGGSGGFVYQR
AYLEFSPARLPAASAAGSNPTFLTHLSPPLQWALSSHGGGRVSFHIADRSGNVNLANFSE
PIAAHLGRLPRLGVAQPTVCDGAAFLAWRDEAFALWNGGVGRLYEEGSPSRRLIESPQQQ
FASPSKGAHKMIGSNVGVSPRGLPRATVRPGTPRGDHLRADSPSRFARHRRPKAAGDFDC
ATGLFAEMFNGEIVRKLNQRFHRDSKKAIAIPPAPQPHPESGRSAAMSAAVSLGTTPAAQ
MFSYSCSGRARAPRAARSWRGRSARTRRWPAGRSVQSQVGRHLGELLELWPVAAGPPR
>A0A410Q5J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caproiciproducens sp. NJN-50|TrEMBL
MRTNELFKRKTVFSFEVFPPKKTSSIDVVYHTLQELNGLSPDFISVTYGAAGGGSNHTVQ
IASAIKNRYGLESVAHLPCINFTKEEVLETLESLKRNGIENILALRGDLSPDIPPKADFR
HASDLISFLKENGDFNIIGACYPEGHPESGGIVKDILNLKKKVDAGADQLISQLFFDNSC
FYSFLERARIAGIDVPIQAGIMPVTNRKQIERMVTLCGATLPKKFVKVMERYGDNPNAMR
DAGIAYAIDQIVDLVAQGVDGIHLYTMNNSYVATKISEAVTSLLKANKITA
>A0A3E0HQ67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kutzneria buriramensis|TrEMBL
MTSRPFQVVCEIEPPTRPDLMHVRHQIGTLSKVADRFLIPDNHIGRATVSSVAVAHEVQA
MGGHSIACLNSRDRNMLGFRRDLLTAAAYGVEEFLFVYGDDPKSGSRTGQLTVRSMIDEV
RSLSEDKAFAGVAPFRIGTAAGLRPLPKWKHAADFMFVQVSFSIDALLRWRDANPVDMPV
YAGVMVIASAGHAQRLSAAIPDIDIPSDLVDRLDGDRLAGVESTCEQVLKIRESGAFDGV
HLVPVARYREVAARLEQALK
>A0A359DC46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLALYQNAGIKRIVALRGDLPSGMGMASGELRYANEL
VSFIRQESGDHFHIEIAAYPEMHPQARNFEDDIANFVRKARAGADSAITQYFFNADSYFY
FVERVQKLGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIESIQAYG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1B9F6G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dissulfuribacter thermophilus|TrEMBL
MIAGSNLETVLKSGQFAVTGELGPPKSGNREVVRKKAKILKGFVDAVNITDCQTAIVRMS
SLTAGLIALSEGVEPVMQMTCRDRNRIGMQADILGAHALGIRNLLCLTGDHQKFGNHPQS
KGVFDMDSIQLLQMVKAMRDEKRFQCGEEIKGGEPRLFLGAAANPFADPFEYRPIRLKKK
VDAGANFVQTQIIYNVDKFKEFMKRVEDLGLTERVYILAGVTPPKSLGMARYMKNFVPGL
EVTDDVIKRLKDAKDVREEGIEIAVDIINQVKEIPGVAGVHVMAIEWEEAVPEIVKRSGL
LPRPEARLEPVLMGMDAIDEAVRKAREEAEARLLEKVDQYKKEAEASRELVAKEKERGAK
EILELRSQIDEKERILQEKEKKIQELLSALKEEKARLEKAHEMGARTIQIEEGDQTIGLE
EDIVSKKQLDYALRSMELGLEALKKVLGLEDEAYEALKRFIEAEFVLKGEGVTEVVQAKV
PPAATPQPEVSAPEVIEEKVEEKAVEERVEEEPKRDKEVVNLVAKANVLLHQGKANEAVE
AFKKALSIDPDDEKAKAGLKEAEEALKKAESVAPASTEGLPPCPEGLTQEEWQRKYVIRL
VATGNCALYEKAQDEAIKYFEEALKLDPDNEKAKKGLEAAQKGEFPSYEAPRDEACAPEE
KVEEQAKEEEKPADVEVVEEVKPTAEEPKVEEKKETQPEKKAEPPKATALDVSGEFTFKA
ETTSLKDRIGDIPEDLFLEKSTGAIKEVVLGDGDKALTVGGASALPFHLFEGDMPYAPRI
AFDVLDSPPEEMPEPLKKYYGDCLDDPVKWAQKCVSEYNAQAICLSLVSTDPNGMDRPSS
EAAKVAKEVIDAVDCPVILWGCGNAEKDTETLREVTALVGDKKVCIGPLTDANYRNLGAT
AMAFGLPVVASTPIDVNLAKQLNILLENLGIGLDHILMDPSIGAVGYGLEYTYSVMERIR
LAALMQQDEKLQAPFICNVGREVWKAKEVKLPSDEFLGDQEVRSILLEAITASSLLLAGG
ELMIMRHPRAVALTEAMIKGLM
>A0A6L3C734|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MKIKDILANTRPVSFEFFPPRAADGIPAVLETLDELKAYCPDYVSVTYGAGGSTRGFTEE
ITFEAKRTAGVEVMAHLTCVGQTKEEIHGVLQRLDAEGVENIIALRGDPPKGDSEYVGVE
GGFQHASDLLEHVKANFDFGVAAACYPEGHTESVDLDSDLQYVKQKVDNGADFLVTQLFY
DNRHYFDFVDRARSAGIEVPIIPGVLPVLNSSQVRRFTSLCGSDIPPDLDKLLDKYADND
NSARDMGVEYATGQVRELWDAGVPGVHFYVLNRSYSVSRILDNLMIPGHLRQD
>A0A6L3C4X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MKIKDILTTTRPVSFEFFPPRSADGIAAVLETLDELKSYCPDFISVTYGAGGSTRSFTEE
ITIQAKRLAGVEVMAHLTCVGQTVEEIDSVLKRLESEGVENVIALRGDPPRGETAFVPVE
GGFQHATDLLKHVTSNYKFGLAAACYPEGHTESVDLDSDLDYVKMKVDNGADFLVTQLFY
DNRHYFDFVDRAKSVGISVPIVPGVLPVLNSAQVRRFTSLSGSEIPQDLDKLLDKYADSD
NSARDMGVEYATAQVRELWDAGVPGVHFYVLNRSYSVSRILDNLVIPGHIRGD
>A0A3P7QWL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brugia pahangi|TrEMBL
MLRFEALLCGTLFFQFFPPKTTNSVANFFARLDRFREGNPMFVDIAWHFGSDPGNISSET
SSSSVAAGCLDYCGMDTMLHITCCPYTKEQSIRHLEQSKALGLKNILALRGDLPR
>A0A8C5E360|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gouania willdenowi|TrEMBL
NNNEIIIFKTRGEYWQGCSSGGDSSKESSRCSTPVLDADRSDRLRDKMRKRIESGDHWFS
LEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCG
LESILHLTCCNQSKEKITAYLNKAKHLGLKNIMALRGDPVGSEWEDEEGGFNYAIDLVKH
IRSEFDDYFDICVAGYPTGHPEAETYEADILHLKEKVDAGADFVISQLFFRADTFLKFVN
DCRAIGIKCPIVPGVFPVQGYQSLRQLAKLSKLEVPEEITRVIEPIKDNDAAIRNFGIHQ
AVEMCRLLLDSGIVPGLHFYTLNREVATMEVLRQLGLWNEDPRRPLPWAMSAHPKRKVED
VRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMW
GEELMNEQSVYEIFTCYITAQSNPCGHKVLCLPWNDEPLAPETNLLKDELEKVNRRGVLT
INSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKILKKYEPRVNYHIV
NVNGRNWTNANDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYED
ESPSRMIVKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLSEAQELLSDGAISE
>A0A372BP29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. JW|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHDFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFECFLEQAQSANIQNLLLLTGDKLKEHHHGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHNYSQQILACVMPLTLARANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYVEQYRHLELKALEELWNSLWQVT
SGNEFSPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALVAK
FLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSIKARLAKAIEQTKILKEKLIPTVPIETRGTSSWKNWYLATEA
>A0A3D3ZSY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Octadecabacter sp|TrEMBL
MSSPAISFEFFPPKSVQASFRLRDCVQTLAPLDPTFVSVTYGAGGTTRALTHEAVDALVK
TSDLNVAAHLTCVDATRAETLAIAKDYKAAGVNHIVALRGDPPKGSNGFRPHPEGFDGAI
DLTRALADEGFEITVGAYPEMHPDASSQQACIDHLKAKIDAGATRAITQFFFEADTFLRF
RDACADAGITAPILPGILPIENWTGVQKFAASCGANIPQVLQDAFAKATDAETTDLLALA
QACELCDDLQAQGVDHLHFYTLNKPELTRDICHALGVTQKQTLQNVA
>A0A5N9BSK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
APSDFCIGGAVDLGRGIEEEAQLAVRKVQAGAEFLITQPIFNVDHVARYRESYAYHAGKA
GTLPIYFGLQILEQDGVLFSSVPESVRADLEGGRSGVDIALELYQEFQKARLNNVYLMPP
IKRGGARNYEAAKEFLTLINKI
>A0A2N1VCR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium HGW-Ignavibacteriae-3|TrEMBL
MKVIEHLSKAKNSLISFEIIPPKRGGNIKQLLEVLEDLVKYNPPFIDITSHAAEVIFEET
SGGGLQMKVKRKRPGTLGICALIQNKYNIDAVPHVLCTGFTREETEDFLIELHYLGIDNV
LAIRGDDSDYKKPIKFGRSVNEYAVDLIKQLDSINKGRYLEDGLLDAQRMDFCIGTSGYP
EKHFEAPNLITDIRHTKTKVDAGASYIVTQMFYNNRSYFDYVDICRKEGIDAPIIPGLKI
VTSKAHVKSLPKNFYLDIPQDLADEIEAAKPEHVLEIGVNWTYKQAEELLNKNVPAIHFY
VMQSSIPIKMLMQKLKI
>A0A640QKD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. KUL150|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVFLRFRDRAAAAGVDLDLVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGA
>A0A5N9ALQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MTTLVELVAKKSRRPFIVCDVSPPRGGSTQLLRSITNVTPDMFFVAANPGGTVRASSLSV
AQWLESNTKIPALFTMTTRDMNKTAMQTTLLGAHVMGLRNLVVAKGDEFPVSGRWTDVSV
KGFTPTAFIRSVKEMNKRTDFTGQALSEPTDFCIGSTLDISRDWGSEISLTGNKVRSGSD
FLIAQPNFEPVLAGKFLEEYQNDQGADLTVPVMWGVQIMSKDSISFTHVPDQVTKELALG
NSGYEIALEMIHKYLEIGIKDFYLVPPIFRGGRRDYESAQAVIEDL
>A0A1H3HPG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter kyonggiensis|TrEMBL
MSKRIPVSFEFFPTKTDVGAEKLRVVHQELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYASDLVA
FIREHSGDHFHIEVAAYPEMHPQAESFDQDIQNFITKARAGANSALTQFFFNPDAYFYFV
DRLQKEGVDLPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNQTEPNRQLVLDLGLA
>A0A3D8L6S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter diazotrophicus|TrEMBL
MKVTEHFQNADKTQFTFEILPPLKGENLQVLYEHIDPLMEFKPPFIDVTYHREEYVYKQR
DNGLLEKISTRKRPGTVGICAAIQNHYKVDTVPHLICGGFNREETENALIDLHFLGIHNV
LVLRGDCVKTESRFVPEPGGHSYATELLQQVVGMNNGCYLDDEQINTNGTDFCIGVAGYP
EKHSDAPNLKADLRWLKKKIEMGADYVVTQMFFDNQKYFDFVNLCRSEGINVPIIPGLKP
LTTKSQLTILPGIFHIDIPCDLADAVEACADNKAAAQVGVEWAIKQSKELMEFGVPCLHY
YSMGKSGSVRKVAEALF
>A0A4V1RKU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides oleivorans|TrEMBL
MRNKQSAATLVRLLKNARYEVLPTATTEDKVLEHLPRDRTITVTASPSKGLDATFDLAER
LAGHGYTAVPHIAARMVTGRTELSEIVDRLSGKGITSVFVPGGDAEAAGDYPDALALLED
LKDLGSPFAHVGITGYPESHPTIHDDLTVQSMWDKRRYATHIVSNLTFDPAVVKDWVRRL
RARGVTMPLLLGIPGPVERTKLLGMATKIGVGESTKFLAKNKGLFARLAAPGGFTGESFL
EKCAPALGEDGALVEGLHVFTFNQIGETEAWRTDMLERLRGS
>A0A8G0Z8X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas germanica|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A7X7U6G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acholeplasmataceae bacterium|TrEMBL
MKISELFSQEKPVVSFEVFPPKPDSPFETVLEAVEALHVLRPDFISVTYGAGGSTHSKTL
ELAQHIKNELGIEALAHLTCISSSDEEIEKILDEIADRNLENILALRGDPPKDCHKQINK
IHACNLIERIAARKKFFIAAAAYPEGHPEASSQEEDLLHLKEKVDAGAGLLITQIAFDND
YLKRFHEKALQHGINVPITAGIMPVFSASQIKHISGLCGATLPPALQNMMEKYSHNQDAL
QSAGIEYACRQIDDLVSYGFAGIHIYTMNRPLLARAILTGTNLR
>A0A8J5HPH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MSSCRPMDLPPRWFKTSHVLGVLLASSPLLEQAWTRCLRANAGSASFIIDRSNAAVFIAF
SRAQAVASPSSLGRGFFEPISLYSSTYELFAPLGRAEEDSGGKPQPVLLQADALRLFMSL
SEKNMKTYVCFTCKQASSAGSIADCKGIRILAMASLFIVVFVHAPYEEEAQCVALCKSDK
MFAVASKDIYGYFNFCGTKVLEELRLTMDQFIDLCILSGCDYCDSIKGLHGNYDALNMHE
YACGEDRPCSEYHQGQWYSKCRSTQGDPPHGQDKFVQVAGGSACTLDPVQHIRAKYGDYF
GITVARYPKAHPDMIQGDEGATLEAYNSDLAYLKRKPPPPEAERSGADPPPMHLCPSTLC
PFFPCRGDPQIVPTIAEGSRSRALVLGSQPVRFGDDWVRFATLMYDPFCKSQTSPHCILR
RECITAIGARTRSVSLLALIRVRFGDDWVRFATLMYDPFCKSQTSPHCILRRECIAAIGA
RTRSVSLLALIRSVTLQNRSVALQHRSVALSLYNIDLPALLLCNTDLSLCNTDLSLSNAD
LSLCNTDMPALSLYNTDMPALPLCNTDLSALSICLSVALQRRSARPVARQYRPTT
>A0A8J5H1M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MKTYVCFACKQASSAGSIVDCKGIWILAMASLFIVVSVHVYRTTAESEMHPMKKKLNVQL
FAKVTRCLRLPQKTYMDTLTFGAPSIKVLDFEFPVVYMETIMHLTCMNMSVEKIDHALNT
IKANGIQNVLALKGDPPHGQDKFVQVAGGFACALDLVQHIRAKYGDYFGITVTGYPKAHP
DMIQGDEGATLEAYNSDLAYLKRKTLSVVLKFWKSFSHVKILELCEIFILWSANS
>A0A7Y3N2K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio plantisponsor|TrEMBL
MGYTHAGHIDALNQNISELSNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLVSAPHLTCIDASREELINIADDYWANGIQNIVALRGDI
PPGGGKPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVMAGIDVEIVPGILPVSNFAQASRFAAQNNVKVPSWMAKQFEG
LEEDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPTR
>A0A8J5H0B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MSTRRCHGFGFSAPLPGKDARASLLLLFSSPLAGRCLRSSLPLTYMTPVSNAAVASSRDV
ATTSPPPTSATSNAGSSLLLRTRPHASKTTTPPLPPSLRDTDHSPPPPFVGSLTYLGHVL
GVLLASSPLLEQAWTRCLRANACSASFVIDKSDDAVFIAFSRAQAAASPSGLGRGFFEPV
SLYSSTHKLFALLGRGEEDSGGKPQPVLLQIGEEYENIRLFRITTAESEMHPMKKKLNVQ
LFAKVTRCLRLPQKTYMDTLTFGAPSIKVLDFEFPVVCMETIMHLTCMNMPVEKIDHALN
TIKANGIQNVLALKGDPPHGQDKFVQVAGGFACALDLVRHIRAKYGDYFGITVAGYPKAH
PDMIQGDEGATLEAYNSDLAYLKRKTLSVVLKFWKSFSHVKILELCEIFILWSAIREA
>A0A6I5IYU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. V28_P6S34P95|TrEMBL
MGYTHASHIDALNQSISEVSDINVSFEFFPPSTPKMEETLWNSVHRLKNLNPKFVSVTYG
ANSGERDRTHSIIKAIKEQTGLIAAPHLTCIDASRDELITIADDYWHNGIQSIVALRGDI
PLGGGKPEMYAADLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPQWMAKQFDG
LDDDPVTRQLVGASQAIDMIRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPR
>A0A3M9XHF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium japonicum|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVGRILNETSLTPAAHMTCVDAARHQVDAVIQEFAAMGVKRFVALRGDPAAGVGA
AYRPHPDGYANGAELVGAMKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A1H7D042|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora phaseoli|TrEMBL
MALGLPSILPNSQPAIGELVRDCQPTFSFEFMPPKDEQGERQLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNMLVVR
GDPPGDPTGEWIPHPEGVHYAEDLVRLVRRSGDFSVGVAAFPYRHPRSPDVATDTEYFIR
KCRAGAEFAVTQMFFDADEYLRLRDRVAAAGCDTPILAGVMPVTRLGTIERSVQLSGAPF
PAALAARFERVADDPEAVRRLGIEQTSEMCRRLLDEGVPGIHFITFNRSTATREIWQNLR
VSAAT
>S0S879|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus avium ATCC 14025|TrEMBL
MSSTLSFEVFPPNTQVGTEKLITTLEELQQLAPDFISVTCSNNRQTIEETTLRVADYIHT
ELQVPTIAHLPAAYLDQAQVQRLVTRLDQIGIHQILALRGDIIPELPPKQDFTYASDLID
YVKQQAPHFHISGACYPETHPESQNRIEDVKNLRRKVAGGCDQLITQLFFDNELFYQFQE
SCDLADIKVPILAGIMPIVNRKQALRLIKTTNTKLPRKFLAILEKYEHDPIALKEAGLAY
AIDQIIDLATQDVAGIHLYTMNNAEVAKHIYYNTKNVLKGQIEVR
>A0A357N680|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MPAGTLQGTRAFIDAGSLEVSAKAMPALRAEAGRIAPGTTISIPYLASEDDEARLAAART
VRELGLQPMPHLSARRIGSQAALEHFIARAVGEAGVEQCLLIAGDLATPAGPFADSAAII
ETGLLERAGIKVVAVGGHPEGHPVMDAAGRWQALERKCQAIEARGMAPKIITQFAFDADL
VLAWLDALRARGIGHPVLVGVPGPASVTRLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPDVFVDRLVAGLTEAHGQVSPHLFPFGGIAPSLDWMAQYRRRSGPG
>A0A349Y540|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAAKLKVFAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASELISFI
RAEHGDAFRIEVGAYPETHPQANDALLDLKHFKTKIDAGADAAITQYFFNADAYFHFVDA
VRKLGVTVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDADSVRAFGAEVV
ASLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLRG
>A0A482PHA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter rodentium|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVSLLKEVADFDVSVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSFAICHTLGVRPAL
>A0A354TYI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium|TrEMBL
AKFTPHPDGFQSSVDLISAIRHYRPELGKRFEISVAAYPEPHPDSLGLAKDLEILKAKQD
AGADRAITQFFFEPDHYFEFLDAARGYGIDIPIVPGIMLQPNFNGLKRIATLCGASLPAW
LHELYEGLEGDAEQRELITANVAADLTMKLADRGVKDFHFYTLNKAGLSLATCRLLGIKP
DKQAA
>A0A1F9BHK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_60_28|TrEMBL
MSAETPSKLQKMINAGHLAVTSEVGPPRSADGVVIEHKAKLIKDYVDAINVTDNQTSVCR
LCSLAACIRIKQMGLEPVLQMVTRDRNRIAIQSDILGAASFGINNILCLTGDHQHFGDHS
SCANVFDLDSIQLALTVRMMRDEGKLLGGHEFEIRPQMYIGAAANPFAGPNVGLRVSRLA
KKVAAGVQFVQTQCIYNMDTFKTFMKMMVDRGLHEKVAILAGITPMKNVGMAKYMQKRVP
GIDVPEDIVKRMGGVPKEKQAEEGLNLAVEQIEELKGVEGIRGFHIMAIEWEEKVPEIVE
RVGLYPRPQPAA
>A0A1X3JAM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli H386|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8J3P173|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catellatospora citrea|TrEMBL
MSDDSVTARRSLRAMLEQAEDGVLLLGITPPRRSVSPEQAAQIAEVTLARLATVDLDGLI
LYDIDDESDRNPQERPFPYLPTMDPVSFHRDHLGSWELPSVIYRCVGKYTEPELADWLGE
VDTDRVLGVFVGASSRDKGVRTGLTQAYALRDRVRADLPLGAVAITERYTRTGDEHLRML
TKQDRGASFFITQVVYDVDATKSLLSDYYYTCAQKGVAPRPVIFTLSVCGSLKTLSFLHW
LGVNVPRWLENALRYSEDPLTESYRQCLVTARELAAFCRRLGVPFGFNVESVSIRKVEIE
ASVELAREVRALLKG
>A0A7W9TJZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Castellaniella defragrans|TrEMBL
MNGSASAISLEFFPPRDIAAQERLVRSAKRLEALRPAYVSVTFGAGGSTRTGTADTVRML
QNLGVDVAPHLSCIGATRAELRAILDDYRARDIRRLVALRGDLPSGMGGDTGELHHAADL
VRFVREHYGDHFHIEVAAYPEMHPQAESAAADLRHFVDKVRAGADGAITQYFFNPDAYFD
FVDRVRAQGLDIPVTPGIMPVTNYTQLARFSSMCGAEIPRWMRLRLQDFGDDKASIRAFG
IEVITRLTARLLEQGAPGAHFYTLNNADAVAQICANLGLDA
>A0A483CY13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHADHPVYILGTIGGLAGDTDATVQR
ATPATIAASVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGMNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFVGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A8J3K8M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catellatospora citrea|TrEMBL
MTLRAPSTMPGPRPTVRELLTSGEPTFSFEFFPPKTADGERVLWQSIRELESLQPSFVSI
TYGAGGSTRDTTVQLTERIATETTLLPLGHLTAVNHSVGELRNVIGHYSDAGVRNMLALR
GDPPGSDPQAEWVAHPQGLHYAEELVRLLKDSGDYCVGVAAFPEKHPRSADFASDVRHFV
RKCRAGADYAITQFFFDWQDWARLRDAAAAAGCDVPIIPGVMPVTNVSQIERMAQLSGAA
FPADLAERLRAVADDPQAVRAIGVEVATELSTKLLAEGAPGLHFITLNRSTATREVWQRL
RVGAAV
>A0A6H1X210|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Romboutsia sp. CE17|TrEMBL
MSLLQEVLEKGEFAITAEMAPPKGTDLSHLLECAKKCVGRVHATNVTDFQSAVMRATSLA
TCKMLKDIGLEPVIQMTGRDRNRIAIEGEMLSAGIFGIENLLALTGDHTCVGDHPQAKGV
FDLDSVSILSTATTLNSGVDSVGLELKGKTNFYLGASVTPEYAPIEVQLLKMQKKINAGA
RFFQTQAVYDIDHLRKFRELTKDMDCKILAGIVPLKSPGMAKFMTANVPGIFVPDDQIER
LKAAGKGNYVQEGIKMAGEFIRQIKEENLCDGVHIMAIGAEENVPLILDAAGL
>A0A4Y6RHJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium tructae|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRIKLSELQPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRASIRAVLADFKAAGVSRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLQAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A2M9CSN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoflavifilum aggregans|TrEMBL
MHVTEHIRKAQKTLISFEILPPLKGKSIESIYQHLDPLMEFKPAYINVTYHRSEFMFKKK
PDGSFEKVEIRKRPGTVGICAAIMNHYKVDAVPHLICGGFTKEETENALIDLNFLGIDNV
LLLRGDPPKNEAYFEPEPGGHRYAVELIEQVVNMNHGIYLEEDLIDGVKTNFCIGVAGYP
EKHYEAPNLETDLYYLKQKIDKGANYVVTQMFFDNQKYYDFVKLCREKGIDVPIIPGLKP
ITSRKQLSMLPRVFHVDIPTELCTEIMKCKNDKEVEEVGKEWLVQQSRELIKFGVPVLHY
YTLGKPEVIKKALAEIL
>A0A2A9D2Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serinibacter salmoneus|TrEMBL
MSTSDLYSASRPTVSFELYPPRTPKGEAQVWETVQRLAPVADYFSVTYGASGTTAERSEA
LVSRILTQTSVPVIAHLTCVGRSRSQLRGVVEAFLDLGVRDFLALRGDPPAGESEWTPAP
DGFARASDLVALIREVETERFGAPPRDPVERLAAHRAGRGRVSIAVAAYPGYATPDGGFR
VRQDELAALRAKQDAGADFAITQLFFDPGAYDALLAAARGAGIVLPLVPGVMPLTDPARI
RRLCDMNTIPHPGELLGELAACGSPEVAERVGMEVTGAMVRRVLRRGAPGLHLYTFNQHA
GVLRLLDGVLQA
>A0A2A9P0S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amanita thiersii Skay4041|TrEMBL
MKFTEKLSASPKPFYTFEFFPPRTDQGFENLIPRIARLAALNPLAISVTWGAGGTTKDRS
LDLAGLTQSAYGLDTIMHLTCTNMEEGMIDEALKNAKDRGIENIFALRGDPPRGAEEWLP
IDPRFMHGTDLVKYIRSNPEYSSHFCVGVAAYPDGHPESTVEDEDTEIDYLKSKVDAGAD
FIITQLFYDVDRFLTWIEKVRRKGITVPIIPGIMPIQTFASFKRITKLCGTKVPAAIITT
LESIGHDDQLVKDYGVSLVVEMLKRLIQVETISGVHFFTLNLEKSVQLILESLQWTVRHE
QIHNKLIADISDSTDPSYTVESNLLITPITAANSAAMGLVSIPNIDGEVGRGELNNAATW
DDFPNGRFGDFKSPAYGAQGLWDGPAISNSQLISQWGSVKTLSDLTNIFLSYLQGEITGT
PFSQMPLSLESMTILPQLEKLTKRSWWTVGSQPAVDGVDSSDKVVGWGPRGGFVFQKSFV
EFFCDKEDVDMVERKARQANGLVHWLAANNEGECRTNMPQEARNAVTWGVFPGQEIVQTT
IIECESFLLWKDEAFSIWSDWASFYRPGSEERTILERVHDERWLVSIVHHDYKNPQNLWN
FLSEMITNGV
>A0A2E2II52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp|TrEMBL
MSKKTVISCEFFPPKTEKGAQNLLVVQERLAVLKPEFYSVTFGAGGSTQDNTLEAVIAVQ
QRAAETGIDAAPHLSCVGSSQERIRTILQTYIDNDISRVVALRGDLPSGMRDPGDFRYAN
ELVEFIRKETGDHFTIEVAAYPEVHPQAQDAGVDLENFKRKVDAGADSAITQYFFNIDSY
LYFVERCQKKGIDIPIIPGIMPINNYSQLARFSSACGAEIPRWLKKRLEEFYDDTESMQA
FTTDYLTDFTEKLLGLDVPGLHFYSMNKSQPVLTVCERLGLVR
>A0A2E5AE79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanicaulis sp|TrEMBL
MTVMGRSSSQGPKVSFEFFPPKSEEAEAKLWSSIERLYPLAPDFVSVTYGAGGSTRDRTH
RTVRRIVAETDMKPAAHLTCVSATCEEVDEVIRDYWDAGVRHIVALRGDPPEGLGERYQA
YPGGYGNSADLTRGIKAIGDFEVSVGCYPEKHPDSADWDADLDMLKAKIDAGATRAITQF
FFDPDVYFRYLERVRKAGIDIPIVPGVMLQPNFKGLKRMAQMCGAHIPDRIHAVYEGLDE
DPDTRELVTAHLAAEMCETLNQGGADAFHFYTLNRAGLALSTCALLGVKSLQDVKAA
>A0A326KT82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MASLSEARALLLSPLGPVARAGSNHAPVRVSFEFFPPKSDDAEASLWKAIRRLEPLNPAF
VSVTYGAGGSTRERTHRTVQRIIAETALRPAAHLTCVEASRDEVDEVIDSYKAIGVDHIV
ALRGDPPGGDGIGGVYRPRADGYANATELTAAIGRAGGFEVTVGAYPEKHPESPSIDHDI
DVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFNGLKRMSAA
CGAAVPDWLAAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRADLVYAI
CRVLGVREQKAVAQ
>S9S0N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubellimicrobium thermophilum DSM 16684|TrEMBL
MSVAVSYEFFPPRDLAASFRLWDTLQALAPFEPAFVSVTYGAGGTTRTLTHEAVTTIRQT
TGLPVAAHLTCVEQTREETLAIAESYAAAGVKDIVALRGDPPGGEARFVPHPEGFASSVE
LIEALAATGRFRIHVGAYPETHPEAPDAQAGIDWLRRKFDAGASSAITQFFFRPETFFRF
RDACAAAGLPAERIVPGILPVQSWAGARRFAERCGTAIPPATAQAFENAERDGTTRLLAL
ATATSLCERLIAGGVEHLHFYTLNRPDLTRDICLALGLRPRVRLQAVA
>S3BC72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 336 str. F0502|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIAPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVESCKNNNEVKQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A2G1MDW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limimaricola cinnabarinus|TrEMBL
MTRPAVSFEFFPPKNIEGSFRLWDTVQALAPMEPEFVSVTYGAGGTTRKLTHEAVDAIHK
KAGLRVAAHLTCVEATRAETMEIVDGYAKAGVEEIVALRGDPPKGSGGFRAHPEGFAGSV
ELIEALAARGNFRIRVGAYPERHPDAAHELADVEHLKRKFDAGAHSAITQFFFEADTFFR
FRDACVKAGIEGPIIPGILPIENWKGAKKFAGMCGTSIPQVVADGFEHAKDQAEADLLAT
ALATELCDTLIAGGAEHLHFYTLNKPDLTRDVCHALGITPKAALSEVA
>A0A1Q9PVT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. MRMR6|TrEMBL
MTLLEKLKQQILIADGAMGTLLYSFGKDSCFEELNLSRPEKIQEIHKAYIDAGADIIQTN
TYAANYLKLQRYGLEDSVKEMNSAAVKNAKLAAQKDAFVVGTMGGNRGIRPTSISIEEIK
RSFREQLYCLLLEGVDGLLLETFYDLEELETVLSIARKETNLPIIAQVSLQEPGFLQDRT
PVNRALTRLEELGADVIGLNCRLGPHHMLLALEQIEIPNTAFLSAYPNASLPTYTDGKFH
YEGDADYFRKSARAFRNEGIRLLGGCCGTTPDHIRAFATELKNSAPVTKKVVKLEQTRII
VESQAVKREFKPLEEIVKERSSVIVELDTPRKLDTSKFFAGAKALKEAGIDAITMADNSL
AQVRISNESLGYLVKQDLGMRPLIHIACRDRNIIGLQSHLMGLHTLGMHDVLAITGDPAR
VGDFPGASSVYDVSSFELIQMMKQLNEGLSYSGKDLGQKTAFSIAGAFNPNVRSVEKAVK
RLEKKIEYGADYFISQPVFSQEKLLEVYEHTKHLKAPIYIGLMPLTGSKNAEFLHNEVPG
IKIAQSIRDQMAALSDNPVQAALEGITITKSLIDAALDLFNGIYLITPFLRYEMTTELAI
YARQRAEEVRGNSNYAESSFH
>B9IXP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus (strain Q1)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6S6ZHG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter kerstersii|TrEMBL
MSLISSHTTLPARNITDAYSLEVSARDIAALTAAGSRIVPGSTISIPYLPGQDDDARLAA
ARAVRGLGFEPMPHLSARRIVSLAGLDSFVKRAAAEAGVERCFVIAGDPSSPMGPFADSA
SLIETGVFERAGIRVLGVGGHPEGHPVMSAADRWNVLERKCRSISERGMAPLIITQFGFD
ADAVLMWLTALRERGIEHPVCVGVPGPAGIAVLARYAALCGVSACASMWSKYGISLGKLF
GTAGPDVFVDRLAAGLTAAHGKVSLHFFPFGGVAQSVRWIEQYRSRAQPLRHASA
>A0A6I4QB21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella sp. Pra-s60|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVQPKDDF
RFASELVTFIKENGDFNVIGACYPEGHLEASTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYSFLDKAYDMGIKIPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMAKYEHHPEAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKSE
>A0A2M7YCK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium CG_4_9_14_3_um_filter_71_31|TrEMBL
MDDQAKATRAPSISFEFFPPKTPAAALNLWRSVERLAPLGPKFVSVTYGAGGTTRERTLG
AVAAIRERARLEVAGHLTCVGATRAETLAVARAYRAAGCARIVALRGDPPKDAGRFTPHP
DGFASSLELIGALGREGGHHITVSAYPETHPEAASPQADIDMLKRKIDAGAADAITQFFF
DNATFLRFRDACAKAGISATIMPGILPVENFEKMRRFAEGCGASVPDWMARAFANTQTEE
EARLLSVSIATAQCTGLMAEGVAHLHLYTLNNPDLPYDVCQAIGVAPQADRVAMAGGA
>A0A0P7VHE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanicaulis sp. HLUCCA04|TrEMBL
MPEGRIAPVSGAPRISFEFFPPKDEAMDERLWNSISRLAPLDPLYVSVTYGAGGSTRDRT
HRTVRRIVQETTLKPAAHLTCVNASREEVDAVIRDYWDAGVRHIVALRGDPPGGVGERYE
PFKGGYANAAELAAGIRKCGAFEVSVGCYPEKHPESASFDYDIDLLKAKIDNGATRAITQ
FFFDPDVYFRYLDRVRGAGIDIPIVPGIMMQSNFAGLVRMAGLCGATIPARLFDLFDGLE
SDPGTRELLTANVTADLCHELSDRGVDQFHFYTLNRAELALATCRLLGVRPVEMAA
>D6IGL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli B185|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0F2RJE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp. BRH_c22|TrEMBL
MNTLSIADRQTTSAPSISFEFFPPKSDAMAERLWETVERLEPMAPDFVSVTYGAGGSTRE
RTHDTVKRIAGSTSLRPAAHLTCVSATKEDVLAVADAYWEAGIRHIVALRGDATEGMGAA
FQQHPGGFRDSVELIEGLRARRPELGKQFEISVSCYPEPHPDSLGWDKDIAFLKAKQDAG
ADRAISQFFFEPDTFLRFLDRARDGGVTMPIIPGIMLQPNFNGLKRISALCGASLPNWLH
RLYEGLDDDPETRDLVTATVAAELCHKLADHDVDTFHFYTLNRAGLALSTCRLLGVKPKP
AKAA
>A0A1Q2M8A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbulbifer agarilyticus|TrEMBL
MSDLRISFEFFPPKTEEGREKLKSTREQLQAFNPEFFSVTYGAGGTTRDTTANIVCGLRE
KGVSIAPHLSFGGDNEEIVLGLLNRYKEAGVDRIVALRGDMPSGMGAVAQLVYANELVAF
IRRHTGDHFHLEVAAYPEIHPEAGSYDDDIRYLKGKFDAGANSALTQYFYNPDAYFYFLD
QCAKAGIDAPIYPGIMPITNFTNLARFSRNCGAEIPRWLKYRMESFSNPDDVKKLGLEIV
TDLCETLLEGGAPGLHFYTMNQVGPTASILDALQLTREA
>U2RS60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia aquatica ATCC 14665|TrEMBL
MSVPLIDHPEDLMSCTTARYSFELYPPRNERAAAALPATIDRLAAARPDFISVTYGANGS
SRTSSLDVLRHILERTDVSPMAHLTCVGSSHEEANRLIREFLDAGVRRFLAVRGDPPEGA
APGEDGIGDIRSSAELVQLIHRVQAERVPYGELTVPGLPAQAVLTRREHVQIAVAAFPNG
HPASHSISQDIDALLAKQAAGANLGITQLFFHAEDYLSFAQKAKDAGVAFPILPGIMPVT
SPARLSRMLELSGEDLPSDLAIQLEVEPTDEGRREIGIEWAAGLGRRLLDGGAPGLHLYT
FNQSEAVLSVLDRIGVLPAPDSISSATEREPA
>A0A1H1XHY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas prosekii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGNHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A3S3NC09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dinothrombium tinctorium|TrEMBL
MGRGLKSFASNSNCDINQFNSQLRSDAFTLAQRIKKYNESKDVPFFSMEFFPPQSADATI
NLISRLEKIREANPMFCDVTWHGTGTPDGKAQTSSLNVAGMMLNYCGITAMSHVTCVSVD
KNSLHLYLERAKELGVRNVLALRGDKISEKNLKQRDFTYAADMVKYIRQNHGDFFTIGVA
GYPCKHPEAESYEKDIQHLKEKVDCGADFIITQFFFESDSFIKFAKDCRQVGIKVPISAG
IMPIQNYSSLKKIIRISGIEAPKHILDTVKENAAFTTRVQKYGIDLATDMCKQIIKSGSA
DGLHFYTLNNENSSVAVLKNLGLWHTGVQRPLPWLHIPSEKRFHEEVRPIFWRNRTKSYL
FRTSEWNIFPKRKWSEYSSQSYKTLDENYYMCLGRTSYSPNELLEMWGKELSSEKDIWDV
FYNY
>A0A6G9SMU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolypothrix sp. PCC 7910|TrEMBL
MPDTQIPTVLNTFRSAAQAGEFLITAEVAPPKGGDPKHMLDMAATLKGRVHAVNVTDGSR
AVLRMSSLVASAILLQHGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPDAKSVFDLEAVRLLQLIRNLNQGADSNEQPLSDGALDLFVGAAVDPQCASWSGLQS
RFERKLQAGAQFFQSQLITDFERLEKFMDKIATGCNKPILAGIFLLKSAKNAQFINRCVP
GVNIPQHIIDRLAKAKHPLEEGVKIAAEQVQIAQQLCQGVHMMAVKREDLIPQILDLAGV
KPMNLVLTK
>A0A367GYH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SDr-06|TrEMBL
MTTYSFEFFPPKTEAGAQTLWNAIRRVEPLAPDFVSVTYGAGGSSRDRTVEITKRIAAET
TLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPRGPWTPHPQGLTYAYE
LVELVRSLGEFTIGVAAFPERHPRSDTWASDIGHLVAKCRAGADYAITQMFFDVEDYLRL
RDRVAAAGCDTPIIPEIMPATDVRQIRRFAQLSNAAFPEDLAHRLEAVRDDPAQGHAIGV
AHATAMAERLLAEGAPGLHYITLNRSTAALEIHRAVQSSRSLHVS
>A0A410X121|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus chitinolyticus|TrEMBL
MKPELRQVLAQKILIGDGAMGTYLYQQGFPVGISYEELNLIQSEVVADVHRRYYEAGARL
IETNTFSANREKLSKYGLEQEVEAINRAGVELARSSVGQDAYVVGAIGPIRAGMRKNVRT
ADVEDALREQILVLLDTQVDGLLLETFYDLEEMLIALRLIRQLSSIPVICQFATEGISTT
HDGISLEDAFLRLKEEGADVIGFNCRTGPNGILRSLQGVAQLSDIPFSVFPNAGIPDYVD
GRYSYAATPEYFAESALRFADLGARIIGGCCGTTPEHIAAMVKALQGYEPNRSEVYAAES
VSAAERAVVTEAAPQTSVREADVEPTLVDIVKQRHAVIVELDPPRDLDIGKFMEGTKALQ
DVHVDAITMADNSLAVTRMSNLALGMLVKEQHGARPLIHIACRDRNSIGTQSHLMGLHAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEMIRMIKQLNEGIAFSGKPLKKKANFIVGA
AFNPNVKYLDKAVQRLERKIESGADYIMTQPVYDPKLIERIHEATKHLDVPVFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMTGLEGEEGRKEGVAIAKELLDAAMPLFNGIYFMTP
FLFYDMSVQLTQYVWQKAERCELLLSPLLK
>A0A2J4JL88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MKDVREILKKCPLLFDGGMGTYYKAKPGQECEQANLLDPDGILTVHRAYLEAGADAIKTN
TFGLPRMAAAQNPMWDAMADEGWKLAAQAAAKTGAAVFADLGPAPDTEALPAAQIYTALA
ERFAALGAKNFLFETLSSDAGVAEAARQIKEAVPDAFVLVSFAVLPDGYTREGRHCAELV
RSMTACGAVDAVGLNCVSAPGAMRALVQQLGETKLPLAVMPNAGYPVVTRTRVQYQGRPE
YFARELARLAAEGVRILGGCCGTTPAHIAALRAALDALPETLPAAPAAAVSTAAKPEVEK
DDAFLRKLNAGKKVIAIELDSPKDADLTGYLDGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGLNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPLTVFGALNLNARNFDVELRRAQEKLQNGMSGFL
TQPVLSAQAVVNLKKTRETLGEKAKILAGIMPVVSQRNAIFMENEVNGIHVDAEIIERFA
GLDRAQGEELGLEVSVKAAQAAAPYADGFYLMTPFNRIALMERLIARLKDEGIAD
>A0A3D9KIG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella phaseoli|TrEMBL
MKPDLRTALARKPLVGDGAMATYLYQLGLPVGVSFEEFNLLKPDVIADVHRQYAAAGAEI
IETNTYSAQQNKLARYGLEKKVEEINAAGVALARKAVGDGVYVVGSIGAVRGGAGKNIRT
AVVKRDFEEQIGVLLASGVDGLLLETFFDLEELSLALGIIRKKSDISVICQFAVEDPERT
HDGIPLADAFRRLKGEGADVIGFNCRSGPTGILRAVETIPADLGLPLSVFPNAGIPDYVD
GKVVYSATPEYFGLSARRFADAGAKLIGGCCGTTPEHIAEIAKALNGYSPVAQTTAPAPV
ESPAIVVEAAPAPVEPPQDVEPSIVDLVRERHTIIVELDPPRDLDITKFMAGAQALKDAK
ADALTMADNSLAVTRMSNLALAALLKERVGIRPLAHIACRDRNLIGTQSHMMGFDALDID
HVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKAKFVVGAAFN
PNVKHLDKAVQRLERKISAGADYIMTQPVYDPELIVRIAESTKHLSVPIFLGIFPLASGR
NAEYLHNEVPGIQLSDAVRQRMSGLEGAEGRAAGVKIAEELLDVAMEHFNGIYLMTPFMA
YEMTVSLTEYVRARSGSLNRKQAN
>A0A7S8INV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. INR15|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKSDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILKETSLTPAAHMTCVDAARHEVDAVIQEFADMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVA
GSAAA
>A0A6I5YXC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. CAP-1|TrEMBL
MLMFSDILAHYSIEATAKDVGAIIIADGLPCPAEVYVPYLPEESDASRIEACAMIRRAGL
EPVLHLSARRLTSLMALETLLAALRDQAQIERVFLIAGDLAQPVGPFSDSLSVIETGLLE
SHGIRTVGIAGHPDGHPDVADDVMWQSMDDKLAALGKRGLGSQIVTQFSFDAQQVLTWLR
AVRARGVTEAVRVGIPGPTGVRTLLRYATRCGVAASAGAIAKYGLSLGRLLGNAGPDRFV
SELRAGLDPAETGQVHLHIFPFGGFAQTADWLVRSGARSPDCRAA
>A0A851ETD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dryoscopus gambensis|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A843C7P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosarchaeum sp|TrEMBL
MTVIYEINPPKISEGKDASNDEINSLLSKLQQRVSNISTLCDGIHVTDSVLGTRRVSALT
TGELLKSNHPDLQITISMRVRDKDMNSIKQIVQKSIEIGLDGILVLKGDPSSDNSVDSGL
IPSQVVKQLNELGYGEKMSFFLSLPSNPNFEKIQKKITAAPEGFMTQVIHSATQVQRISD
KLRPSGFRIIPCILLPSEKNENSAKFLNLDWLEYKENPVKFIKEIHNIAGDVLITSPSDF
TFAKDTLQNLQSTKY
>A0A291T971|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MKDIRELLQTRPLLFDGAMGTYYKAAPGVECEQANLTDPAGVLAVHREYLAAGADAVKTN
TFSLPRLAAAHTPGWEQLAQAGWQLAVQAAEETGAAVFADLGPAPDTEAVPAGQVYTAVA
KQFAALGARNFLFETLSSDAGLLDAVGAIKAEVPDAFVLVSFAVLPDGYTREGMYCKDLA
RRMQESGIVDAVGLNCVSAPGAMRTLAKQLGGTLPLSVMPNAGYPVVTRTQVKYQGRPEY
FARELGRLAAEGTVQILGGCCGTTPAHIAALRAELDSLPVVEKTTSTEEFSTVKEQTVEN
EDAFLRKLNAGEKVIAIELDSPRNADLTGYLEGAKKLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGLCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPGPMTVFGALNLNARNFDVELRRAKEKLENGMSGFL
TQPVLSAQAVENLKKTRETLGADAKILAGIMPVVSQRNAIFMENEINGIHVEDWIIEKFA
GLDRAQGEELGLAISLEMAKAALPYADGLYLMTPFNRVALMERLIGRLKQEVLGAY
>A0A2A7ANK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MDDIRAFLSRKPLLFDGGMGTYYKAAPGVDCEQANLTDPAGVRKVHAEYLAAGADAIKTN
TFGLPRLAAGHVPGWEKLADAGWKLAAEAAAETGAAVFADLGPAPDTEAVPAAQVYPAVA
ERFAALGAKNFLFETLSSDVGILEAVRAVKAQVPEAFVLVSFAVLPDGYTREGVYCKDLV
RRMTESGCVDAVGLNCVSAPGAMRTLARGLAGGALPLSVMPNAGYPVVTRTQVRYQGKPE
YFARELSGLAAEGAVRILGGCCGTTPAHIAALRAALDALPERKLSAEPAKLSTTEVKPVE
NEDAFLRKLNAGEKVIAIELDSPRNADLTGYLEGARKLQAAGADLLTIADCPIAQARMDS
SLVACRVHRELGMCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEV
KNVYQFNSRKLAQYIVSLAGEDREMPTPMTVFGALNLNARNFDVELRRAGEKLENGMSGF
LTQPVLSEQAVENLRRTRETLGSRAKILAGIMPVVSQRNAIFMENEINGIHVDEEIIQKF
AGLDRAGGEELGLAISLEMARKALPYADGFYLMTPFNRVALMERLIAQLRTEVLQES
>A0A5N5P025|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coniochaeta sp. 2T2.1|TrEMBL
MHIREMLADAERTGEPSFSFEYFPPKTAQGVQNLYERIERMYNFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYFGLETCMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPPREKEK
WVATEGGFQYARDLVRHIRDTYGDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGATF
IVTQMFYDVDNFLRWVDKVRARGISVPIIPGIMPIATYASFIRRANHMQCKIPDGWMSRL
DPVKNDDVAVREMGKVLVAELCRKILAAGIRHLHFYTMNLAQATRMLLEELDWMPSVNRP
LKQALPWKQSLGLGRREEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEENRRKWGEPRSVADIASMFVRYLEKKIEALPWSESPLTSEADSIKDDLIA
LNKRGFLTINSQPAVNGVKSSHSIHGWGPPNGYVYQKAYIELLVHPDVFPEMVRRIEANP
DLTYYAVKREGDFTTNAPNEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGTDW
ARCYEPETPSRLLLEDMMEHWYLVNIVNNDFHQPRTIFEVLDGLTVPGLDTVPQPEPATN
GVHHTETATAAAA
>R9NIP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea sp. 5-2|TrEMBL
MKIRDILKSEEPHISFEVFPPKTDAGYDSVLAATEKIAALKPSFISVTYGAGGGTSKNTV
SIASHIKDDFGVTSLAHLTCVSSTKEVVHQVIGELKENGIENILALRGDIPSEYEFPLPN
HYRYASELIEDIRQQGDFCIGAACYPEGHVETEHKKDDIINLKHKVDCGVDFLTTQMFFD
NHILYNFLYRIREKGITVPVLPGIMPVTNKKQIARIGGMSGTILPERFRAIVDRFGDDQK
AMQQAGIAYATDQIIDLIANGVNHIHVYSMNKPEVAAAIIRNLSEIVKN
>A0A178MUX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum moscoviense|TrEMBL
MNSPLPIAVASAQPVKVSFEFFPPKTEKMQETLWECVKRLEPLAPAFVSVTYGAGGTTRE
RTHDTVVRIARETSLKPAAHLTCVGHVQGEVDDIARRYWDEGIRHIVALRGDAPEGSGAY
VPTPGGYGYAVDLVRGLKRIADFEISVAAYPEMHPDAPSAAFDLDNLKAKVDAGATRAIS
QYFFDPAVFLRFRERAVAAGITVPIVPGILPVTNFAQVQKFSAACGASVPGWMATLFEGL
DNDPETRRLVAATVAAEQCRALAADGVSDFHFYTLNRADLAYAISHILGVRPRG
>A0A5C5VWI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrimarina hoheduenensis|TrEMBL
MRLPDIYAQTDFALSFELFPPKTEAGLEALFGHADRLMRFAPSYITCTYGAGGSTQDKTL
EIAARVRREYHLPVATHLTCVGRTADQIRDYLRRAQEADVQNVVALRGDPPQGETEFRPV
AGGYSYANELVDMIHHDFPDMGVAVGGYPEVHQEALSAAADLDNLKRKVDAGSHAVITQL
FYDNADYFRFRERCDAVGVNVPIIPGLLPVTNVAQVKRIASLCGAQLPADFLGLLEGASE
DAAAQFEIGVQQATAQSQGLIDGGVPGIHYYVLNKSEAASRVLEAVTLSDR
>A0A1U9RNR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataeibacter nataicola|TrEMBL
MTDRLNGLVSEQRIGNLLSCSRDMPTPALSFEFIPPRTEPMEQRLWQCIRRLAPLSPHFV
SVTYGAGGSTQASTYATVLRLRRETDLVPAAHLTCVGATREEVDAVARRYWEAGVKHIVA
LRGDPPAGAVGYTPHPGGYAYASDLVPGLRRIADFDISVAAYPETHPAALSPEADLDNLK
RKLDAGATRAITQYFFDASTCLRFLERCQSAGITAPIIPGIMPVSNYEHVARFSTLCGVT
VPVWLTRLFEDTDGNLELRRIVASIVAVEQIRTLQTNGINEFHISTLNRADPTFAIAHIL
GLRTTGRCMSDNVADYSEQEETTDEREAETESDTPGRAEEGASPFMLRTMFG
>A0A3D0CPL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp|TrEMBL
MTSQTPSLSFEVFPPNPAVGDEKILRALEDMQELAPHFISVTASNNKYNIKETTVPLADY
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNSNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQAVAGVHLYTMNNAETARHIHGATHSLFKHHSQVSAL
>A0A449IGR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fragi|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDINNFVRKAHAGADSAITQYFFNADSYFR
FVERVQAAGVMIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQAFG
EQVISEMCDRLLDGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A086ZJN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bohemicum DSM 22767|TrEMBL
MHSPVFSLEVFPPKNSSPVGTIYDTLDGLEDVHPDFISVTYRQGALADRTVTARIAKTIN
DEYHIPAVAHLTALYNDEQAIDQALDMFEEAGVKAVLALRGDFIEGVEPCGVFSHASDLA
AYISRRKPGMRIYGACYPECHVEASNLQTDIDNLKRKIDAGVTRLITQLFYDNADFYRFV
DLARARGIDVPIEAGIMPVRSVKSLERMTSCNGCCLPPAVKAMADRWRDNLPALKQAGMV
YASQQIADLVAHGVDGVHLYAMNRPRTVRKIWANVSPLFDEAA
>A0A2D3WIX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp. UBA12169|TrEMBL
MFETFCKNLHNDQPFITVEVNPPHGASLDPIIQMIKASNLASKVSGFSCTDNPLAKLKMS
GVLSAIRLQQTFGKPVIATMSMRDKNKLSLQSEVLGANDFDVRCILALTGDPAKYSDQPE
VKGVLERDSTLLLSIIYHLNRGVDYSNKPLNPAPKPIYPFAVSNAYAKDMKKLQKRIVKK
LDYGARAIITQPVYDLENAKELLEIFEEAKALSIRDTAKEAQLILGQFPLVAAKTANFIN
DKVPGIHVPKVIIDEMNLASMDGAEKEKEVGFALSKKIFDEMMKLHGKVHLMTHNRFDLC
SELIG
>A0A085EJR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium gilvum|TrEMBL
MKVTEHIEKAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYQVDTVPHLLCGGFTQEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKVGGNNYAVDLVAQINQLNHGKYLHDVMDIDNKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYIVTQMFFDNSKFFEFVKKAREMGITVPIIPGIK
PIAVQKHLQILPQIFRIDLPEDLINAVEKCKNNAEIRQVGIEWAIQQSIELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A2Z6UHK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa Sj|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDMAGIPPIHN
>A0A524NQI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidia bacterium|TrEMBL
MALFTPGRRWQPPFFPFKREPLGKRVLRKIERWIKGPLFGCRMCGNCLLQETAFICPMEC
PKGMRNGPCGGSSREKCYVDETRPCIWYKIYERAHKMGREEILMEVLPPLDWDKVGTETW
GDVVRSMRKYGTAAFLRDRFSRDKERKHQSWEAVFQPVRQPSWWKGDSRYHPPAYEEPIS
RLESDLKSGKFVITAEVSPPLSTATEKLKRDIEMVNELVTAINFTDSASASPRMSSMACS
KVAAELGADPVLQIAAKDKTRSGLQSDIMGANVMGVHNVLCISGDNARIGPTPTSNTNIL
DMDAIQMLWILRRMRDEGIYLDGRKMKSSPRLFLGAAASPFASEPKFQALREQKKVHAGA
QFFQTNLIYDPDRLDLWLEELYKRDILDKVYILAGVTPIRSRRMAQYLHHTIPGVTLPEH
ILERF
>A0A242WSY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar cameroun|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTNRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQVALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7C6LYX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKIKDLYETKSTVISLEIFPPKWDSPIETVFKTLDELKDINPDFISVTYGAGGKAKDRTV
EIAAKIKNEYNIESLAHLTCISSTKEQVRECLEELRRHNIENILALRGDIPEDPDFDFPE
PLHYQYAADLISEVKEEGNFCIGAACYPEGHVECESKIRDVKYLRDKVSVGVDFLITQLF
FDNELFFRFMEEIDLAGINIPVSAGIMPVLNKNQIERMTKLSGCYLPNKLKRILDRYENN
PAALKEAGEAYAIEQIIDLMAWGVRGIHLYTMNKSDTAKRIIGNIENIRKLQNR
>A0A429JRE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC 06725|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVQHPEGVLYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATQLCARLMAEGSPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A015TT46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis str. 3998T(B)3|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKK
>A0A5H7IKG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Mapo|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTNEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A354MPH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MGEVRPDEDAENGWQEERKMSVMESLSRHNTLSFEVFPPRTEAGRRELLEPDGVLDRLNR
ESPDFLCCSYGAGGADAGKNLEVLDAVVSTGRSQAMTQLTCAGNTAEGIREQLRNYRGRG
VSCVMAIQGGEGRMSWGLSDEAELVKLIRREFGNEFLVAADGAPEGEPLGSSLEGEINRL
KAIQEVGADFLITRLCWDMDIFHIWLDGIRAAGITLPVMAGVAPVVDQAATIRTALATGG
CAIPEELCRLLSDYWIYPNPFVKDPFDAEVERKRTQFREAGAAYTVRQIRLYRRWGVDGI
HFLTQNRAEDVLAIARAARDTSF
>A0A0M8MLB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malassezia pachydermatis|TrEMBL
MSGDESCKITHKIAKAKKEGRVWWSFEYFPPRTPQGLTNLYDRIERMAQLGPAFVDITWN
AGGRTSDLTTQLVKTVQAYFGLETCMHLTCTNMPRSKIDVALREAKAFGCRNILALRGDP
PASGGEWEADAAGFSHCSELVQYIRANYGDYFAIAVAGFPEGHPEAKDGPEAEMEHFKAK
IDAGADFIFTQMFYDLDAFVDWCKRIRAAGITVPIVPGVMPIQNYGGFTRAVARFRAHVP
QYFHDALDPVKDDDEQVRLVGQKLVGDMCKKILEHPDLDVNGLHIYTMNLERGSRMLLEY
LGLTPSVQQLNPLPWRQSLTPKRRDENIRPIFWANRTKSYVNRTDGWDEFPNGRWGDARS
PAYGDVDAYGTHLRFTKEEALELWGEPNTLDDLKDLFVRFCAGDLKSLPWSDTPVAKETK
VIDQHLIQLNKRGYLTINSQPPVDGVPSSDPVHGWGPKDGYVYQKAYLEFFVAPEQLDEL
LQRIEAHPQITYHAVNAQGDMRTNTTSDAPNAVTWGCFPHCEILQPTIVESISFLAWKDE
AYEIGRRWAHLYPEGSTARTMLSNVFDTWFLVNVVHNDFKKAEVIFEPFLV
>A0A0Q8N2S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. Root186|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSINELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAIDLVRQINDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFNFVAKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A1B9P7R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliivibrio sp. 1S175|TrEMBL
MAYSHASHLESLNQNIAELDGSINVSFEFFPPSSEKMEETLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLIAAPHLTCIDASRSELIDIANDYWANGIKDIVALRGD
IPAGGGVPDMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQASRFAKMNNVKIPGWMAQQFD
GLDDDPVTRQMVGASHAIDMTRILSREGVKDFHFYTLNRAEHTYALCHTLGVRPKG
>A0A8B1N616|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces auratus AGR0001|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWVKHPDGVAYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVD
KCRAGADFAITQMFFYPEDYFRLRDRVTAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A6N9CZ02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MEISHLSFEFFPPRTEEEFRNLTRSADRLQQENPDFFSVTYGAGGSTKDRTYHTVQKLRN
LGLNTFPHLSWGDSSKLTMLEQVSEYLRLGIEGMVVLRGDLPSGADGQLSHSPKDLVALI
RQHFGEKLLIFVGCYPEVHPDADTMKTDLRFLKEKVDAGATACITQYFYNVDAYIRFVDE
CQRIGITQAIIPGIMPLYNYHVLVKFSQNCGADIPRWIERRMYEYREDKSALEAFGIDVV
SRLCTRLIESGAPGLHFYTLNRALSVKKILKNLEITTESSNEMTEKK
>A0A890CYX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida auris|TrEMBL
MSTVTSRIRSLAPGERFCSFEFFPPKTDAGFRNLLARLSRMMALNPLFLTVTWGAGGSTA
EKSLDLAATCQKELGVTTVLHLTCTNTNKEVIEDALQRARAAGIKNILALRGDPPRTEEY
WTPNCDFSSAVDLVRYIRQNHGDYFCIGVAGYPEGHVEGADASQQDPRKDLPYLVEKIEA
GADYVVTQLFFDVDKFVAYEKLLRETPQLKNVILIPGLMPITTYRVFVRATRLSHANVPR
DILSKLDAFANDDDTVKTIGLDVLTKMISEIDQRTEGRIRGYHFYTLNLEKAVASIINRS
PVLQNMISHNKSVEHDDAVASDSDEEFAPPMKNGRRKSSVNENQVAVPDDAKRALVSKAL
SKDPKSIVDISTGKGALGKDATWDEFTNGRFGDSNSPAYGEIDGYGPNLKLHTNKEVEET
WGNPESTADITRIFVDYLSNKINVLPWADSELSPETGLIQEELFELNERGWFTLASQPAV
NNCKSSDKILGWGPPNGHIFQKSFVEFFIPKKQWKDELLPRISKQVEEKTITYYCGDASG
HISSNLPIGKGKDSNTKSAVTWGVFPSKEVLQPTIIDYESFKAWNEEAFLLWLEWARCYR
KDSKSYQLLNDIYNNYYLVSLVHHDFTDEFVLWTTLLSD
>A0A7X1LGE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. AQ_MP|TrEMBL
MTKPERPIAKIPAARISFEFFPPKSPDMEDQLWQTVKALQPYQPDFVSVTYGAGGTTREP
TLATVKRLINDTPLATASHLTCVGATREEVHAVVEEFRAAGVRHFVALRGDPQGGVGTRY
EPHPGGFVNAADLVAGLRQIGDFEISVSAYPERHPESGTDDVDLDMLKQKVDAGATRALT
QFFFDNDIFERYLERVRKAGITIPIVPGIMPIQNLTQLKRFASMCGASIPAFLDERFEGT
EGDALACAAVAADIAAEQIADLANRGVHEFHIYTMNRAPLTIATLERLGVTGRNDRLSGA
AA
>A0A6G7YJD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides piscis|TrEMBL
MTRGPGRSMRELIESGEKSFSFEFFPPKDEAGEERLWRAITELEPYRPTFVSVTYGAGGS
SRDTTVRVTGRIATETSLTPVAHLTCVGHSRAELLEILDAYKDAGVDHFLALRGDPPGGP
HTEWVSTDDGLEYASELVAFIKEHYDAAVGIAAFPEGHVNSESLEHDAQVLKAKADAGAE
FAVTEMVLRASDYFALVERARAIGVDMPIIPGIMPILSLRSMNRMVELSGRVMPREVTSR
LEPLAETPDLLRAEGIRISTELCDELLAGGAPGLHFYTLNFSRATREIFQALQITV
>A0A850AF66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaceae bacterium|TrEMBL
MHVVDAITNAREPLLSLEITPPPKGTSIDELYRTMDALMPFKPAFINVTYHQPQVVYEEK
NNVIYRVPKRKKPGTVGICASIANRYSVETVPHFICGGFSKFETEDALIDLHYLGITNIL
ALRGDPAAGNTQFIPERDGHRYASELVNQISRMNRGIYMEELEDAHPTNFCIGVAGYPEK
HFESPNAEKDIQHLKHKVEQGAHYIITQMFFDFQYYKDFVERAREAGISVPIIPGVKPLS
NLDQLASIPRNFHVTIPHHIVEAMEQARTSEEIRKAGIRKIADLCQKLIDYKVPGLHIYT
MGRGTATRDLLKILYG
>A0A4V6NGL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineothrix alysoides|TrEMBL
MKIQQYLQNEKIICDGAFGTYFSAITEEEMLPEKANIMRPELVKRIHASYLEAGAVLIRT
NTFASNRVSLQCGESDVKENIRCAWRNALEAVSVSGRTLGEDCFLAGDIGPIPMDSGTPE
EDIFREYKLICDTFLSEGADILLFETFSDLDRILPVIEAVKKEREVFVIVQFCVNQHGYS
NAGISAGRLLREAGEAVQIDAVGLNCGVGPGHLYTILDKIEFPEGKYITALPNAGYPKLI
KNRMIFRDNAEYFSRKMKDVSLRGVDILGGCCGTTPEYISLLKEAVDLRQVKKEAAGHRA
EEVKIQPGNSSFWKEKGKGEKLIAVEISPPPGADDEKVMEAAFFLKEHKVDVITFPDSPS
GRTRADSILMSMKVAQETGLCVMPHICCRDKNAIAMRSQLLGAYINGIRNMLVITGDPVP
TLIRQEVKSVFNFDSVGLMKIVSELNQEEFAKDPVTFGGALNHNRPNLEVEVGRVKKKMA
QGAGFFLTQPVFTLEEAKKLRYVKEQTEAKILCGIMPLVSLRNAQFIKNEMAGINVTEEV
IARFLPEMTREEGERTGVEIAKEVIGFTEDFVDGYYFSIPFNRVYLVEKIFQK
>A0A3D3BZT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDSENSPFSIEFYPPRNAEGESRLDAVHAELAKLNPDYFSVTYGAGGSTKTGTSKLVMKY
QAAGSQVAPHLSFGGTDEQEVLELLQTYKEAGIKRIVALRGDIPSGSGAPMHYRYANELV
KFIRKETGNYFHIEVACYPETHPEAKNFSDDVAFFKQKVDAGANSAITQYFYNVDAYFRF
VDYCDSQGINVTIVPGVMPITNFDNLKRFSAKCGAEIPLWLGKRLEDFGDDVTGLKQFGQ
DVVTELCYDLLQGGAPGLHFYSMNLSKSVSQIWSELGLQDRNT
>E5AEI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMDRSLVDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGQLPEQDSNKDFTWAADLVRYIRKQYGDYFCIGVAAYPEGHSDESHPEHQSPEHDL
PWLVEKTKAGADFIMTQLFFDVDAYDRFEKLLREHESGAFKTMPIIPGLMPIQSYKILLR
TTKLSHARLPPNMLARLDAVKTDDERVKQVGVQILDEMVEHIKGRSNVGRRGFHFYTLNL
EKAVSHIIEDTNLIPRDLPEDDDSAIFETTPAINLVPPPNGTMSRRRRSSVTSSPRNRVI
VSQPSATKSSNHSYEALDSEAGIPRGPVNTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTAQALKLWGHPVDRDDISDLFRKHLEGELDALPWSEQTLSD
ETLTIKKELLALNKKGWWTVASQPSVNGVRSTDPVFGWGPRNGYVFQKPFVEFFIPSEAF
ATLKPRLEAHEQITYFAANAAGEFEATDEEAVNPVTWGTFAGKEIVTPTIIEAVSFRSWS
EEAFSIWKEWQCVYPSKSASAKMLGEMRKDLWLVNVIWGDFVNGEGLWEFLDG
>A0A3M1UTR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNTEKTFSFELFPPKTEKGMANLQETVRRLNERRPAFFSCTYGAGGSTRDRTFATVDWLV
SQGIETAPHLTCIGLSVAEALQILDRYRRQGIRRIVALRGDPPSGTGLAGGEMRHASELV
QLIREHHGDHFHIEVAAYPEMHPQAPNFFADLDHFKEKMAAGANSAITQYFYNVDAYTHF
IDQCLARGMEAPVVPGIMPITNYGNLARFSDACGAEIPRWIRKRLESYADDVESIRAFGL
DVVTELCEKLLAAGAPGLHFYTMNQADPTLSIWDRLGL
>A0A5F1S8S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. SEMIA 4088|TrEMBL
MSSRSESHNAGIRISFEFFPPKSEEAEQQLWNTVEELSDWDPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLATGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVGALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKAKNGADRALTQF
FFDNDAFERYHDRVRAAGIEIPVVPGIMPIQNLTQLKRFAGACGASIPSWLDERFDGLDD
NIEERAKVAADVAAEQIQDLVGRGIHEFHIYTMNRSPLVSAVLERLGLQRKVASRAGAAA
>R6T074|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:57|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A496VGU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPKKLSISCEFFPPRTEKGVLKLREIRKQLQVLQPTYFSVTFGAGGSTQEKTIETVLEIQ
QESDFDAAPHLSCIGSTRETILKLLRDYQAQGIHRIVALRGDKPSGWAGNLGEFNYANEL
VSFIRAETGSHFQIEVAAYPEYHPESHSAKEDLNYFKQKVTAGADGAITQYFYNADAYFR
LIESCTALGIDIPIIPGIMPISNYEQLARFSDTCGAEIPRWLRQRLKDLADDKAALQDFG
VEVVTKLCERLLAGGAPGLHFYTLNQAELTLKIATGLGFL
>A0A1G1HTL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium RIFCSPHIGHO2_02_FULL_42_12|TrEMBL
MKIARLLKNKRQIFSFEFFPPKTDEGEKRLFETIENLKELGPSFVSVTYGAGGSTRDKTA
GWVIRIKNELDIEAMAHLTCTGTSCENLKRILDKLQENGIENILALRGDKPQDTNSIAQM
PQCYNHTNELIQYIHDNYDFCIGAAAFPEGHTESPSLEKDTYYLNMKSMAGAEFFITQLF
FDNRLYFDLLDRASKIGINKPIIPGIMPITSADQVERFTSLCGATIPSDLRERLHEIRND
RRAVMELGIGYATKQCQDLLSKGAPGIHFYTLNRSSATRTILKNLL
>A0A534CGB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNAESGRTPIRVSFEFFPPADEAMGAMLWKSIERLAPLAPRFVSVTYGADGSTRERTHNV
VTRIQRETPLTGAPHLTCIGASREEILEIARGYWDEGIRHMVALRGDPPQGEGARRPNPR
GFRYASELVAALARLAPFDISVAAYPEVHPEAASAAADLENLKRKIDAGATRAITQFFFD
TDAFLRFRDALAAAGVHAPIVPGILPITRFPQVLRFAKACGTSVPGRLHERFAGLDDDHE
TRRMIAASVAIEQVEALRRHGVSEFHFYTLNRAELTYAICHALGLRPHARSASAARQEAP
A
>A0A3D5Y5Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSSLSQALASDEFVVTSELTPPKGTDLSTLLNKAEKLKPHVTAINLTECHTARMAMDPVA
AGHLMLDRGIEPIVQMTCRDKNRLAIQASVLGAAALGISNIVFMGGDPPKNGDHPEAKPV
FDLYSAQLLEAAHALASGTDLMGNALSGTPTLFPGAVTNPGAADLDAEIDNLQRKAAAGA
CFFQTQAVYDAEAFAAFLEKARLEQPMLAGIIPIKSVKMANYMNERIPGVEIPDGLIARI
ADAGDDPKRVAQISIDIAAETVRKLRSIARGVHLMAIGWEKHIPEILARAGV
>A0A1F4A0E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_64_12|TrEMBL
MESQRKHPRAFSFEFFPPRTEQGIEKLRATWRQLAQLKPRFFSVTYGAGGTTRERTLGTV
LEIREAGYEAAPHISCVGSSRADIAATIELYRSKGIRHIVALRGDVPSGTASPGELRYAS
ELVAFIRERTGDHFRIDVACYPEFHPQARSPQDDVLNLRRKIDAGANTAITQYFYNADGY
FRFIDECEALGIEVPIVPGIMPIGNFVQLARFSDACGAEMPRWLRQKLASFGDDLASIRS
YGLDVVTDLCDRLLSAGAPGLHFYTMNQAGLTSIIWQRLGL
>A0A2E2ZFH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTENCKTLSFEFFPPNTDSTMLTLIDLAKEFESIPAKYFSITFSGRGSAQKETFNTVESL
SNSTKIPIAPTISGIGLDSDLVQSILSKYKERGIKKILVFRGDLPPRSQKIGXFTYAVNL
LDFIFEKFGNYFEIEVGAYPEMHPEAANSNEDIXYFCEKMSRDVKGAITQFFFKPEAYFD
FIDKCANLGCTKPITPGVLPXSSKKELEIMSKKCGVELPKDLIEDINGYKDERDVKKFGE
MYITSLVQELLDNGVPGIHFYTLNKLEPTKNIINLLN
>A0A349E6Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDVSNPSKFSIEFFPPRTEAGEAKLDTVHAELCKLNPDFFSVTYGAGGSTKAGTAQIVLR
YHAAGSVCAPHLSFGGADEEEIRQLLRSYTDAGIKRLVALRGDTPSGVGTSVQHHYANEL
VEFIRRETGDHFHIDVACYPEIHPESKSYASDIDFFKRKVDAGANSAITQYFYNPDAYFR
FVDYCGDAGISIPIVPGIMPISNYANLARFSANCGAEIPRWLDKRLQGFGDDVESLRNFG
IDVVSELCEDLLAGGAPGLHFYSMNLSQSVSQIWTNLDLGNRNQNELP
>A0A523M9P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTTHSKTAPVQVSFEFFPPKTEKSEATLWSTVERLAPLQPRFVSVTYGADGSTRDRTHRI
ISRVNAETALTGAPHLTCVDATQSDVDEIARGYWDDGVRHIVALRGDPPQGAKTYVPYPG
GYEYAVDLVSGLRNVADFDISVAAYPEVHPEAQSPLADLDNLKRKLDAGANRAITQFFFN
VDSYLRFRDLATTAGITAPIVPGILPISNFASLQRFAAACGAAVPDWLHEKFSGLDDDPE
TRQMISASVAIELVEKLQREGVDEFHFYTLNRAELTYAICYALGVRPKADDKGVRPRSDD
KGVGPGADYEGVTPGAKSDGPPPAKASKGSA
>A0A3T2URU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella flexneri|TrEMBL
MSFFHASQRDALNQRLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A356QVJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
FSEPISFRPLRIAKKMAAGVDFIQTQMIFDMDIFRQFMRRLVDLGVTEKVHILAGIGPLK
SSPMARFLNENIPGIVIPEDLLKRMDGAVQGISEDNKEARRDAWRAEGQDICIEQIKELQ
QMEGVSGVHIMAIEWEAAIRQIVERAGLLPRPIV
>A0A2E0EYA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNYSLEFFPPKDQESFKDFIDQARLLSIFSPEYMSITHTADTVDNNQTMEAVKILKKNLS
VEIKPHMTCINYSKSEIMEMAQNYLSLGVDSIVALRGNTKQSASNREPYYDNSLDFIKAL
NAGFDIRVSISGYPEAHPESRGVIADFIXLKEKSDXGXDEIITQWCFSNDLILRYRDLCY
ARDIKIPISPGILPISDIKKVKYFAKLCGSTIPVEIEKAFLNIEGNDDAAEDLGVQFAIQ
QIDDLLNEGIDNFHLYTLNRGDMTRKIIEHFEAPNRIKTVSSEMKAS
>A0A1V0K9E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lactucae|TrEMBL
MTRRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAEDLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A2E8K5W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNGKSPIEKRFSFEFSAPKSEDAIQQLKKVHKRLSECNPHFFSVTYGAGGSTKDGTRQAV
MDIKHTGSEVAPHLSFGGDSPEKVEQLLLEYKNAGVNRIVALRGDAPSGMGSSGNLIHAD
KLVTFIREKTGDHFHVDVAAYPETHPESINVESDLKYFKQKLDAGANSAITQYFYNADAY
FRFVDSCKKLQIDVPIVPGIMPITNYKGLVRFSNNCGAEIPRWIVQHLQTYENDPESLKS
FADEVVTDLCQRLLEGGAPGIHFYTLNKSLPTIRIWRNLGL
>A0A523LGE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKPVKNTEPVATVQTNTDPEHTDPFSIALHELSLEIGVHDLEALDRNRHLLPTGGRIYVN
AVAGEGAEARIRTAAQLTALGYQPVPHIAARRMRTAEELDDYLVGFVERAGVSEILVIGG
DLVEPRGPYASALEVINSGVPAKHGIRRIGIAGYPDGHPNIDTTVLKQVLAAKLAACRTA
AIDPYIVSQFSFQAESIINWCRAIHEEHPDLPIHAGIPGPAKLRTLLRFARICGVQSSAK
KFLANKKMGFDLLRRAAPWDQMEAIGQYRLETGRPLSAHLFTFGGISETVSWLQKVRTDR
RPNSGVVRF
>M1LVE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium saccharoperbutylacetonicum N1-4(HMT)|TrEMBL
MIREYLKKNILIFDGAMGTYYAESTGNDISYCEFANLEDKDSIKKIHEQYINAGAKLIRT
NTFSANTYDLNVSLDKLREVIKSGIDIAKEVAKDREIYIGASIGPIKASSILDEAPENIL
NEYKFIVDCFLENNINVFVFETFSNYSYIEEISKYIKDKDRNSFILTQFAVKPDGFTRDG
VSIKKLINVVKSIKEIDAYGFNCGSGPTHMSEIIKSINIDNDIVSALPNAGFPELIHERT
VYPNNPKYFAKKVNEIRLQGVSIIGGCCGTNPNYIKEIVALVEGKFEKIKVIGSNNKEEV
VEKEFCIENSFRSKLDRNEFVIAIELSAPADTDITKLMNGARICKENNIDLVTIPDSPMS
KVKADSTIIATKIKREIGIEVMPHICCRDKNTNAIRSSLIASHIEDIRNVLAVTGDPISD
ATKIETKSVFNLNSFKLMELINDMNEEFFKGDTIHIGGALNLNVLNKEVEFNRMLKKIEK
GARFFLTQPIYDDEAIEFLKKIKEKTDVKILAGLLPIVSYRNAIFLNNELPGVTIPEKYI
RMFSENMDKEEAQRVGVKISVEIGKKLKDIADGLYFITPFNRVNMLIDIIEEIKN
>A0A7D3XIU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter mangrovi|TrEMBL
MSPTLDQMREAQRALETPLFSGLPGDIEVSFEFFPPKSEKMAETLWQSVETLKPLGPRFA
SVTYGAGGSTRERTHQQVVRIQNEAGIPAAAHLTCVNATREEVDEVARHYWAEGIRHIVA
LRGDPPDGATKYAPHPGGYANAVDLIAGLKKVADFEISCAAYPELHPDSPNAQADIDNLK
AKFDAGATRAITQFFFDPQSFFAFRDKATAAGINGEIVPGIMPVLSFAAVQRMSGLCGTA
IPGWMEGLFEGLDDRPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRPKA
>A0A4Y3PHR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus parabrevis|TrEMBL
MTTSKQDLREYLQEHLLVGDGAMATQLHALGAPVGVSFEELCLSNPRVVHEVHASYYQAG
ARLLETNTFSANRDALSRYGLEHKVARINRLAVAIAREAAKDDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGVDALILETFLDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYSLTDAFPQLKQAGADVIGLNCRLGPAEILRSFESTIFPDDSLLSAFPNAGRLG
MTDGEYAFKSSPDYFAESALRLRDQGVRLIGGCCGTTPAHVKAIADALAGQKPQARVNPT
IALAERPHITVQSIHEREKPSIVERVKTATTIIVEFDPPRDLDAEQFLDGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKTRHGIDPLLHIACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMAAAVARLEKKVEAGADYIMTQPVYDVESIRLVHEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSAEALERMKKVQGPAARQEGIAIAKELLDTAVRYFNGIYLITPFNYYD
MAADLIAYVRQQSALVKTAQP
>A0A7V8V8X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bremerella alba|TrEMBL
MLSEFYKPGELPISFELYPPKTDKGVRSLMLQVERLMKHKPSYITCTYGAGGSTRGKTLE
IVEKVKTLFQVPVAAHLTVVGSSVADLRSFLAEAERRGVDYIVALRGDPPQGETKFKPNP
KGLRYANELVELINDEFNDLGVLVAGYPETHQEAPSPDVDMENLKRKVDAGAQVIVSQMF
FRNSDFYSWRERCEKAGIKIPIVPGIFPINSLAQISKIAKMCGAGIPKKLYEKLNQKPDD
PDWHKRVGTAYASQQVNDLVDNNVPGFHFYVLNQADATGQILTSMREHMAKKKTGSPA
>J8DL60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus (strain MSX-D12)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIVSIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIQKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARVLKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2T6LHA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Promicromonospora sp. AC04|TrEMBL
MSIPTARSIDVRGLLTDHSLEMTGKDVPHLLEARTSIPQGTRINVTFLENEDLRVRIRAA
RTVRDLGFVPVPHISARRFDSEAMLEEYLGALQADGAVDHVFAVGGDPATPHGPYGDALS
VIASGVLQRYGVRSASIAGYPDGHPDISEAELWAALTDKAAALHEQGLAGGIITQFGFDV
DPVIAWVEEVRRRGITLPIRVGVPGPAGIRRLVRYASRFGIGTSAGIAKKYGFSITNLVG
TAGPDKFIGELAERLDPGLHGGVKLHFYTFGGLGATSSWITDRQKEAQR
>A0A673IEQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus rhinocerous|TrEMBL
MSCEQYENILGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHWFSLEFFPP
RTASGAVNLISSIAFSPPPAPSLIWLASALPVRGHVFCRRFDRMGSGGPLFIDVTWHPAG
DPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGD
PIGEDWVEEDGGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVD
AGAHFIVTQLFFRAETFLRFVKNCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEE
IMQVIEPIKDNDAAIRSYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLW
AEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGE
LTDYYLFYLKSKSPKEALLQMWGEELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDP
LAPETNLLKDELEKVNRRGILTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSS
ENVTALLQVLKKYEPRVNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVS
FMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDM
FALLDSPRETQEEGSQS
>A0A7W8N5T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus mongoliensis|TrEMBL
MGLLDDLKQRIVIADGAMGTLLYAHGIDRCFEELNITKPEEIVHIHEAYIEAGAEVIQTN
TYGANYVKLARYGLQDDVKEINKAAVQLAKQASKERAYVLGTIGGLRSTNKSTISLEEVK
RTFREQLYVLLHEGVDGLLLETYYDFEELQTVLSIARKETTLPIIAHVTLHDIGVLQHGM
PLAEALYQLELLGADVVGLNCHLGPYHMLRSLEEVPIPTRAFLSVYPNASLPQYRDGRFI
YETSEQYFEETARAFRDQGVRLIGGCCGTTPKHIAALARALPDRTPVYKKEVKQRHTIVV
QEAEQTKEPSLADIARTRRTIIVELDPPKKLGLTTFLEGAKALKEAHIDALTLADNSLAT
PRISNVAVGTIVKQQLNMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRL
EKKIECGAHYFLTQPLYSEKQIEDVYEATKHLPTPIYIGIMPLTSARNADFLHHEVPGIT
LSDDIRARMAACANDPVQSTKEGLAIAKSLIDAAFDLFRGIYLITPFLRYDMTVELVRYI
HEKERLTKERTVYYG
>A0A124JWV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium fuchskuhlense|TrEMBL
MTTTFDQLREARTALDTPLFAGLPGDIRVSFEFFPPRTDPLMEQLWDVVTTLAPLRPSFV
SVTYGAGGSTRDRTHGTVARIIREARLPAAAHLTCVEASKAEIREVAESYWEAGVRHIVA
LRGDMGAPGVPFTPHPDGYASAADLVAGLKAIAPFEISVSAYPETHPDAASPEADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGITAPVLPGILPVSNVAQTRKFAAACGAH
IPAWMDGLFEGLDHHPASRQLVAATVCAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPERPLMEQAA
>A0A401JAY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuriferula multivorans|TrEMBL
MVKRTFSFEFFPPKTPEGMDKLRATRDQLALLKPKFFSVTFGAGGSTRDHSLETVLDIQR
AGYAAAPHLSCIGSTHDNIRAILQQYQTHGIRHIVALRGDLPSGMASTGEFRYANELVEF
IRSETGDWFNIEVAAYPEYHPQARSARDDLLNFKRKVDAGANSAITQYFFNADAYFNFVD
ECAALGVTLPIVPGIMPISNFSQLARFSDACGAEIPRWMRKQLEGYSDDIESIRAFGLDV
VTDLCERLLKAGAPGLHFYTMNQATLTTTIWQRLGL
>A0A1G7GPU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger thiooxidans|TrEMBL
MKRPEISFEFFPPRNIEATFRLWDTVQALAPLKPNFVSVTYGAGGTTRELTREVVATLHK
HSGLRVAAHLTCVDATRAETLAIAEQFRDAGVKDIVALRGDPPKGASGFTPHPEGFGSSV
ELIEALRKTGDFNIRVGAYPDVHPEAANAAADVEWLKRKLDAGASEALTQFFFEAETFFR
FRDACAKAGIEKQIVPGILPIENWKGARRFAEACGTKVPAWVIEAFEAAERDGRQDLLAT
AICTELCTELLENDVDKLHFYTLNRPELTRDVCLALGIAPETTLENVA
>A0A6B3SG73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPNIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTF
>A0A2T6J965|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. 107|TrEMBL
MNAAHTQGTGFPVSFEFFPPKTPEGVDKLRVARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILSEGVGAASHFSCIGATRQSVHEQLATLKAMGVKRLVALRGDLPSGYGVGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPEADLQAYVTKVRAGADSAITQYFYNSD
AYFRFVEDAHRLGADVPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A1A9GM17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides dokdonensis FR1436|TrEMBL
MPGLFRLPAMTIGRGHALTDLIAAGGRSFSFEFFPPKDEAGEAQLWDAVRALEPYKPTFV
SVTYGAGGSSRGTTVRLTGRIARETSMLPMAHLTCVGHTRRELEEILEEYAAAGVHHVMA
LRGDPAEGPRADWTPTEGGLDHADQLVELVASRGQFRIGVAAFPERHPSSASLDHDADVL
VAKARAGAEFAVTQMFFRASDYFGLVERVRARGVDLPILPGIMPILNLQAIRRQGELIGT
DVPADVVARISAHDGDPVSMRAEGIAQAAELCQELLDGGAPGLHFYTLNRSKATREIFEK
LHVTP
>A0A379AVA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Avibacterium gallinarum|TrEMBL
MSYAKEIDTLNNHLSGINGNINVSFEFFPPKNENMEKILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKHIKQETGLEAAPHLTGIDATPEELKKIAQDYWDSGIRRIVALRGDEP
AGYDKKLFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPAWMAKMYEGL
ENDQTTRNLVAASIAMDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGVCPE
>A0A2W4JNG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermocrispum agreste|TrEMBL
MSSVLSRISGEAPTFSVEFFPPRDAEEEAILWRSIRELESFDPAYMSITYGAGGSKRDGT
IRSIARVAQETTLVPMAHLTAVDHSVAELRNVIGHYAAVGVRNVLALRGDPPGDIHGEWV
PHPEGLNYAYELVELIRSLGDFCVGVSAFPYGHPHSPDLQTDTRYLVRKFQAGAEFAIAQ
LFHEADDFLRLRDRLAAAGVDAPLLPGVMPLTTPRTLHKTIELSGAPAPEWLLRRLEPLA
DDKKAFRAEGLDVTTELCERLLAEGVPNLHFYTFNRSKATREVVTRLGLVPVRA
>A0A660E0N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus mudanjiangensis|TrEMBL
MDFRTALKQRVLVADGAMGTLLYGNYGINSAFEQLNLTHPDTILRVHNSYISAGADVIQT
NTYAANRLKLTRYGLQDQVVAINQAAVKLAVKAQQQADHPVYLLGTIGGLAGDTDQTVQQ
ADTAARQASLTEQLQALLATDDLDGILLETYYNLPELLAALKLVKAQTTLPVITNLTMLA
PGVLQDGTTFADAVIQLAAAGADVVGTNCRLGPYYLAQSFENLAVPANVQLAVYPNSGLP
GTDQDGQVVYDGDPSYFEDYAERFRQLGLNLIGGCCGTTPLHTAALVRGLASRTLVPHTA
ATQPVTAPTIKAAIGRHPFLQKVATQKTALVELDPPKDFETTKFFNGAQRLKAAGVDGIT
LSDNSLASVRIANTTIAAQLKLTYGITPIVHLTTRDHNLIGLQSTIMGLHSLGIDDILAV
TGDPAKLGDFPGATSVGDVRSVELIKLIKQFNSGIGPTGKSLKQATDFRVAAAFNPNAYR
TTVSTKSIERKLSYGCDYLITQPVFDLANVTALADALKTNDIHVPVFVGVLPLVSYRNAE
FLHQEVHGIRLPETVLARMKQAEQDGNERAVGIQIAKELIDGICNVFNGVHLVTPFNRFK
TIIELVDYVQQKNLTPVQ
>A0A6H1W6H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia sp. PS1209|TrEMBL
MSCTDARFSFELYPPRNARAAEALPATIQKLAAAHPDFISVTYGANGSSRSSSLDVLRYI
LDHTDVSPMAHLTCVGSSHAEAAQLIREFLDAGIRRFLAVRGDPPADLAPGETGLGDLHS
SAELVQLIHRVQAERVPYGELPVPGLPASTVLSHREHVQIAVAAFPNGHPTSHGVSQDID
TLLAKQAAGANLGITQLFFHPEDYLGFAQKARDAGVLFPILPGIMPVTSPARLTRMLELS
GEDLPSELAIQLEVEPTEEGQREIGIAWATDFAQKLLDGGAPGIHLYTFNQHEAVLSVLE
RVGLLGAAAPVHQTTTTTTTTDASTTEREPA
>A0A1H2UT52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. CF384|TrEMBL
MKPDLREALQARILTGDGAMGTYLYGMGFPVGVSYEEFNVLRPEVIADVHRRYYEAGARV
IETNTFSANLASLSHYGLDYEVEAINRAGVQIARDAVGSDAYVVGAVGSIRAGKRKNITA
MQLEQLFHQQMDALLNAGVDGILLETFYDLEEALLALRVARKLSDVPVICQFAVEKEAVT
QDGHPLAIAFNNLKQEGADVVGFNCRSGPNGIMRAIDSIVGEIVLPLSVFPNAGIPDYVD
GKYMFSATPEYFAQSARKFADRGARIIGGCCGTTPEHIAAIAKSLEGYTPQPVEPETQQH
QVVQHERITLVPPQQPAEPTIVDLVKERHTVIVELDPPRDLNIQKFMDGARALKEIKADA
VTMADNSLAVTRMSNIALASLVQHQVGIRPLVHIACRDRNLIGTQSHMMGLDALGIDHVL
AVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGIAFSGKALKQQANFITGAAFNPNV
KYLDKAIARLEKKIDSGADYIMTQPVYDKELIVRMAEATKHLSVPIFIGIMPLASGRNAE
YLHNEVPGIQLSDDVRRRMAGLEGEEGRAEGVRIAEELLDTALEYFKGIYLITPFMFYEM
TVQLTDYVWRKTSVKTG
>A0A6G3R1N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID14436|TrEMBL
MALGTASTRTDRARTVRDMLAGGKTTYSFEFSAPKTPKGQRNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVHETEQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNAVF
PDTLKERILTAKDDPATVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A6V7JPY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bracon brevicornis|TrEMBL
NPTIDGDFVYAIDLIKFIKEKYGNKFCIGVAGYPDIHPESPSRNEDIYYLKKK
>A0A412KWS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea formicigenerans|TrEMBL
MTCKIRDILKDQTPQVSFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKN
TVSIASHIKDDFGVTSLAHLTCVSSTREEVHQVIDKLKEKNIDNVLALRGDIPKDNAFPL
PNQYRYACELIEDIKQQGDFCIGAACYPEGHVETEHKKDDISNLKTKVDCGVDFLTTQMF
FDNNIFYNFLYRIREKGILVPVLPGIMPITNKKQLRRSMELSGTAVPQRFLAIIDRFGDD
PEAMKQAGIAYATDQIIDLIANGINHIHVYSMNKPDVATAIMNNLSAILKVED
>A0A518BHP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium Pla133|TrEMBL
MRISQMHGLGAPVFSFEFFPPKTPEAVEELVSTVAELRDMHTPDFVSVTYGAGGSTRETT
LATIARIQNELKITAMAHLTCVGHTAAELKTIVQQLVDAGVENILALRGDPPKGETEFTR
TSGGFGYASELVGFLQQNFDVCIGGACYPECHPESKTRADDLDYARQKVAAGASHLTTQL
FFENRDYFEYVERARKMGIEVPIVPGIMPITNVKQIQRFTKMCGAQIPEALLGRLERVAD
DPGAVMAIGIEHAILQCRDLIAGGAPGVHFYTLNKSYATRSILAALRGLRTR
>A0A558B810|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter vinifirmus|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQVVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LSLHKQGISTAPHLSCVGGTRAEIGELLDLYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIRNHSGDHFNLEVAAYPEFHPQARSAEDDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGITIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISDREKIAF
>A0A1A9DBE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. OspMP-M45|TrEMBL
MRELLATGKTSYSFEFWAPKTAKGERNLWNALRRVEAVRPSFVSVTYGAGGSTREGTVRA
TQQIAADSTLTPVAHLTAVDHSVAQLRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSDDWDSDIRHFVDKCRAGADYAITQMFF
HPESYLRMRDRVVAAGCDTPVIPEVMPITSIRQLERFAQLSNASLPSSLKERLLAAKDDP
AAVRSIGIEFATEFCAELVSEGVPGLHFITLNNSTATLEIYENLGLHRQS
>A0A1C0AHZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus lapidicaptus|TrEMBL
MPSTDPKPGTVAELFRSAHGPLFSFEFFPPRSEEEEPVLWAAVEALAPLQPAFVSVTYGA
NGSRRDRTIRATRRIAESGGPLTVGHLTCVAQSKAELAEALAEYLEAGVTNILAIRGDMP
GGGPWERHPEGLANATELVRFIKSEGDFCVGVAAFANPHETSNDPDLDARILLDKVEAGA
EFAITQLFFEAERYAELVERMRGLGCEIPIVPGIMPLTVITQIERFAALSGRALPDALVS
RLRACASKEEVREAGLAAAVQMSRDLLAAGAPGLQFFTQNRSKATREVLAEVLTTAR
>A0A1F6GSG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lambdaproteobacteria bacterium RIFOXYD2_FULL_56_26|TrEMBL
MPNARKIQNLYAYNTHVSFEVFPPKTNQGLKQIYQTIARLKGMSPDFFSVTYGAGGSTAE
KSLDIASAITNLAQVTCVAHFTCAHLSRPQVLELLQSLEFHGINNVLALRGDPPQGQGTF
VRPQDGFGYASELVAFIREHSKVGILVAGYPEGHMENPDKEDDFRHLVQKVEAGADGIVT
QLFFDNRFLVEFKEKLDRAGVQVPLVAGIFPLSNLKQLDRIASMSKNYVPPRLKAGLEKW
ANDPESMEQFGTDYAIEQVQGLLDLGFRDFHFYTMNRYQQTRNILFALKDYFPRLKFD
>A0A847NWS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp|TrEMBL
MHIADILKNNKVAFSFELFPPKDKNASDQLFTAISELVPLKPAYVSVTYGAGGSTRELTH
DLVMRIQNETNLTVVSHLTCVGSSKAELFAILEKYHDSGINNIMALRGDPPRNNPSLGKH
PDGLLYASELVRLIKTNFPDMGIGVAGFPEGHPETPNRLQEIEYLKRKVDEGADYICTQL
FFDNRDFYDFCERCELAGINIPILAGIMPITSRKGMIRMAELALGARFPARLLKALARAE
DDQFFEKVGIHWATEQVRDLLDNGVKGIHFYTLNRSNATVQIYNQLGVSCSSSLSK
>A0A6J7ZSM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktothrix rubescens NIVA-CYA 18|TrEMBL
MNRFRTACQTLDEFIVTAEVAPPKGADPSHMIEMVRLLKGRVHAVNITDGSRAVLGMSSL
AASIILLHHGVEPIYQLACRDRNRIGLQADLLGAQALGIRNILALTGDPVKAGDHPDAKA
VFDLESVRLLQAIDKLNQGKDWNNKTLPDGATDLFPGAAVDPQSSSWSGLKSRFERKIEA
GAQFFQSQLITDFDRLDKFMTEIADGSKKPILAGIFLLKSAKNARFINKYVPGVCIPDTI
IDRLEQAKHPLEEGILIASEQVKIARELCHGVHIMAVKREDLIPKILDLAGIKPLF
>A0A7X7E4D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp|TrEMBL
MHIAEILKNHKVSFSFELFPPKDEVSSEQLFKAISDLVPLKPAYVSVTYGAGGSTRELTH
NLILRIQKETDLTIVSHLTCVGSSKSEIHSILEQYQKNGILNIMALRGDPPKNSGTFVKH
PDGFNNAAELVAYIKKNFPEMGIGVAGYPEGHPETPNRLKEIEYLKMKVDAGADYICTQL
FFDNRDFYDFCERCTLAGIQIPILAGIMPITSAKGMQRMADLASGTRYPARLLKALARAE
DDEHFEKVGIHWATEQVRDLLDNGVKGIHFYTLNRSKATLQIYDQLGVTTSDALSR
>A0A8J1VQE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tremellales sp. Tagirdzhanova-0007|TrEMBL
MRITDKLAKAEREGRPFWSFEFFPPRTAQGLQNLFDRIERMRELGPEFIDITWGAGGKNA
DLTSSLVQVCQETIGLECCMHLCCTEMPREKVELALAQAKSHGCENILALRGDPPKGTST
WEPTPGGFYRAADLVHFIHEHYPGDFCVAVAGFPQGHPETSDTDEGRNQEITWLKEKVDA
GADFIFTQMFYDTDILFNWVRRVRAAGITVPIVPGIMPIQNWDKFQTWVKRENIVVPPHF
YEALNPVVGDDEK
>A0A702BP67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella bongori serovar 44:r:-|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A101CCN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium aquaticum subsp. greenlandense|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICASIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHGSAMELVHQINDLGRGKYLHNQDEICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEDLINEVENAKNNEAVKQIGIEWAIAQCRELLEFGVPVL
HFYSMGKSDNIKKVAGALF
>A0A3B8FES1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MLRSETARHNGEIRGDIRLSFEFFPPKNPEMENQLWETVAELKKWDPDFVSVTYGAGGST
KAPTLDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIG
TDYRPHPQGYENAAALVKGLRDISDFEVSVSAYPEKHPESASDAVDIDMLKRKADNGATR
ALTQFFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPSFLDERF
AGYDDDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSA
A
>N9UTS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. MC1|TrEMBL
MTTSLDALAEARRAAASPLFANLEGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLAPRFV
SVTYGAGGSTRERTHATVARIASESAVPPAAHLTCVEASRAEIEEVARAYWDAGVRHIVA
LRGDVPGGGAYRAHPEGFANAVELVAGLKRIAPFDISVAAYPEVHPDADCPQGDLDNLKR
KLDAGATRAITQFFFSPEAFLRFRDAAAAAGIDAPIVPGILPVSNVSQTRRMADMCGTAI
PAWMIALFEGLDDLPAARQLVAATVAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHMLG
LRPVAPAKDKAA
>J4Q5U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. BS35b|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFEIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHRATHALFNHQSLG
>A0A5B8J7D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces qinzhouensis|TrEMBL
MALGTASTRTDRARTVRELLATGQTSHSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATEQIASDTTLTPVAHLTAVNHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVRHPQGVTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVD
KCRAGADYAITQMFFRPADYLTLRDRVTAAGCATPIIPEIMPITSVGQLERFAQLSNAAI
PEELKDRILAVKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYENLG
LHEQV
>A0A344W298|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantimicrobium sp. MWH-Uga1|TrEMBL
MSNASPSSSRELSIGVPFSFEVYPPRNPELRDALHATILELAASGPDFISVTYGAGGSSR
DATLECVKYILDNTDVEPMAHLTCVAESYQGANELVRTFLDAGVRSFLALRGDPPQGTQE
GEDFLGDLGSAAELTQLIHRVQAEREPFVFVEEPRWHAGATRLSQKREFVRIGVAAFPNG
HPQSRSKTQDIDVLLAKEAAGANLAISQLFFHADDYLSFAQKAKEAGLRMPIIPGIMPVI
SPGRLRRMIEISGEDMPSDLEIALEIEPTVEGQREIGVEHAANLARELMAGGAPGIHLYA
FNQSGPVLDVLRRLEA
>A0A1H0P0U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium sp. YR620|TrEMBL
MTIHELKAKPMTKIAASIEVAARQAIESQDLPGLFPAGTRVYITDMGTDSVDTLTAAAKR
VHDLGYKPVPHFASRRLSTRAALETRIRRAAEEAGVTDILVIGGGLERQAGEFSSTMQVL
ETGFFDRYGINEMGVAGHPEGSPEFSEAVALQALRLKKNFGERTGAKLRVVTQFGFDAER
FIRYAESLREHGIDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNALSLTALATSH
SPEGVVGPIEQHVIANPMSAIKQIHLFPFGGLKKTSEWLVERGSWNVNNAQYSSANAAAN
>A0A4D7Y0C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MRSETARHDGDIRLSFEFFPPKNAEMETHLWETVAELKKWNPDFVSVTYGAGGSTKAPTL
DAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIGTAYRP
HPEGYENAAALVKGLREIGDFEVSVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQF
FFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFEGYDD
DLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVNAVLENLGLERLRRSAA
>A0A0A2WKB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter dokdonensis DS-58|TrEMBL
MALSVPVSFEFYPPKTDEQRLQLDRTAARLKSRAPDYVSCTFGAGGSTLSYTPETVQRLR
DQHGLEAAPHVSCMGGTREELRSLLKLYRALGCNRIVALRGDLPSGMARMGDLRFASELV
EFIRTEHDGFFHIEVGCYPEMHPQAEDAFADMRHFKAKADAGADGAITQYFYNADAYFRF
VDDARKLGITIPIVPGIMPISNFTQLRRFSEACGAEIPRWIGKRMQAYGDDSDSIRQFAS
EFVADLCSRLVDGGAPGLHFYTLNLSKPTLNVLELLD
>A0A329QJQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytoactinopolyspora halophila|TrEMBL
MSRGLPSTPQGNGPAIRELLAAGERSYSFEFSPPKTPEAEGLFWRTMRELERLRPTFISV
TYGAGGTTRESTVRLTGQVALDTTLTAMGHLTAVNHSVAELRHVIGQYADAGIRNILALR
GDPPGDPQAEWTPHPEGLLYSEQLVRLIKSVGDFSVGVAAFPEKHPRSPDVETDVRYLVG
KFRAGADFAITQMFFNVEDYLRLRDHAVAIGGDKPIIPGIMPVTNVKQIQKFAELCGAAF
PESLAERLYAAGDDREAVRAIGVDYATAMCERLLAEGTPGFHFYTLNRSPATREIYERLG
LVDNTLAPA
>A0A430L6J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium euwallaceae|TrEMBL
MDRITDRIAALPADGSYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRREE
YRDPDDSEDDGGQDFNWAADLVKYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVEAGADFIMTQLFFDIKAYEHFENTLRDHPSGAFKTLPIIPGLMPIQSYQMIKRT
TKLSHAQIPEDILARLNAVKGDDEKVKMVGVDIVSELVEKVKDIKSKTPGPKGFHFYTLN
LEKAVSFILERTNLIPEPPEDEEALVVDDAIPIPALQVNGSSNLRSGSHSRSRASRRHSS
VGSDPHNRVIVGDRPATHPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDF
PNGRFGDARSPAYGEIDGYGVSLHMSITQAVKFWGHPKTRQDINDLFVKHIQGELSAIPW
SEEELLAESSTIQPHLLRLNQKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEF
FIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVSSDKGGHVDGSSDAGPSTNAVTWGV
FPGKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSDSEKLLSGIKDEYWLVNLIHH
DFVEKDALWQVLSS
>A0A558BWQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis rhizosphaerae|TrEMBL
MTTVVERLRGEGPAFSVEFFPPRDAADESVLWRSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGEWV
PHPQGLTYAEELVSLVRSLGDFCVGVSAFPYGHPRSLDLDSDTKYLVRKFKAGAEFGIAQ
LFFEADDFLRLRDRVAAAGSDALLIPGVMPLTTPRTLHTTIRLSGAPCPQHLLDRLEPLA
DDPKAFRAEGLDVVTELCQRLIAEGVPDLHFYTFNRSKATREVVARLGLVPARA
>K5W8I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phanerochaete carnosa (strain HHB-10118-sp)|TrEMBL
MRLADKIANYEGERPFFTLEFFPPKTDQGFENLLARISRLAALGLLAASITWGAGGSTRE
RSLELAGITQQEYGLDTVMHLTCTNMEKGSIDEALKAAKERGITSLLALRGDAPRGDEEW
IPTDPRFVHGADLVRYIRTLPEYSNFSIAVAGYPDGHPESQTDEDGEIEYLKQKIDAGAD
LIITQLFYDVDGFLRWERKVREKGITVPIVPGIMPIQTYASFLRLTKLCGTRVPHKLMAD
LAEIRHDDQKVKDYGVKLAIEMIERLTSEANIPGVHLCTLNLEKSVQRVIEGLGWGAPNY
SKITNKLIADISGTSTPTSAIPRQSDFTITPQKATDSATSKLAVIANTETEAGKGELNSA
ATWDDFPNGRFGDYKSPAFGGPNPWGTTTVSRNQVLAHWGHPKTEEDILNVFLRYLHSKI
ITTPFSPEPLSPESLMIIRHLEWLTKKCWWTIGSQPAVDGAKSSDEVVGWGPKGGYVYQK
SFVEFFVEKDVVDKIEKKVRERGQGLVDFFAGNLEDDFRTNVPKGGRNAVTWGIFPGQEV
AQSTIIEKESFLAWKEEAFNIWAEWASHYPPDSEERRLLQSIRNKRWLVSIVHHDYKDPD
ALWRFIYDDGEPLV
>A0A4D7X9F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MRSETARHNGDIRGDIRLSFEFFPPKNAEMEAQLWETVAELKKWDPDFVSVTYGAGGSTK
APTLDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVIEEFRNAGVRHFVALRGDPSTGIGT
AYQPHPEGYENAAALVKGLREIGDFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRA
LTQFFFDNDVFERYMERVTVAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFE
GYDEDLEGRARVAAEVAAEQIADLQRRGFNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A8G0XLW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MG28|TrEMBL
MALGTASTRTDHARTVRDMLATGKTTYSFEFWAPKTAKGERNLWNALRRIEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADTTLTPVAHLTAVSHSIAELRNIIGQFAGAGIRNILAVR
GDPPGDPLAEWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSPDWDSDVARFVD
KCRAGADYAITQMFFHPESYLRLRDAVASAGCETPVIPEVMPVTSVKMLERLPKLSNAAI
PNALKERIVTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A6J4TVV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Thermomicrobiales bacterium|TrEMBL
MAHPLVSRLADQILLADGAMGTMLYAAGIDLDASFDALNLERPQVVAGVHRAYLAAGADI
IETNTFGANRARLEHFGLADRIRDINLRGVKIAREEREISGRPALVAGAIGPTGRTLAPF
GTADPLAVRAIFQEQIEALLEGGVDLLTIETIGSLDEMVEAVTAAREASDLPIVALLTFA
EDGRTLAGNTPEDAVIRLADLEVTAVGANCSVGPQRILPVLRAMGEALATRQGDRPALAC
MPNAGWPTHLGGRVIYRSAPDYFGDFARQAAMAGVRIVGGCCGTTPEHTRTMRAALDTLV
KVSVGDPPADGEGSAPAAPNGTGGKAVRGVPDLRGVDLVPSEGPTEVAEKLGKKFLVSVE
IDPPKGFNPAKALDGARLLKAAGVDAINVADSPMARVRMSAMTLCYLIQHQVGIETILHF
TTRDRSLMGLQSELLGAHAVGVRNILALTGDPPSLGAYPDSSAVYDVDSIGLIRVLTQLN
AGNDSAGASIGRMANFTIACAIDPTRTDLHEEARRLRAKLEAGANFVMTQPIYDLNVWTR
FLDVYEQVHGDRELNVPVLLGVLPLQSSKHAEFLHNEVPGITLTDEARDRMRKAGPDGRR
EGVAMARALLEEARPHVQGVYIMPSFGRYEVAAEVIEVLRVDR
>A0A6B9ZGX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga agri|TrEMBL
MGLTLTDKIKSGNSGLTFYSLTPPKITTGPERIAEIAKGQLERISALDIDGLILYDIQDE
STRTDQERTFVFTPTLSPEEYSRKYFQELQVPKIIYKSIANMNGDRFKQWLTDNSDVAYS
VFVGASSQQQVEQTNFTLRDAFTLRQQHAPSLLIGGVTIPERHAKKGDEHIRLNDKTGQG
CNFFVSQCVYNVNDTKDLLADYYYHSCEKSFSPAPIVFTLAPCGSLKTLQFMEWLGIKVP
KWLFNDLKHSKDILQSSIHTCLNVASEILEYADKKNMAVGFNIESIAIKKEEINASIELL
GEVIRLTKPATRAAASQLLADVPAVL
>A0A8H4EJW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gigaspora margarita|TrEMBL
MKVKTKIQKAQEEGRPYWSFEYFPPKTQQGVQNLYDRMERMYRLGPEFIDITWNAGGTSS
QLTSEIVSTAQSVYGLETVMHLTCTNMPKEKIDKALKDAKDCGCQNILALRGDPPRGQIE
WEACENGFSYAIDLVRYIRSQYGDYFGICVAGYCEGHVDNPDKDDDLRRLKDKVDAGADF
IVTQVFYDVDLFLDWVKKCRAIGITCPIIPGLLPIQNYNGFNRIVSLSKTIVPKFVCDAL
EPIKHDDAAVKEYGIKLAVEMIKKMYNNGISGFHFYTMNLERSTRLILEALQFVAPVEKV
KPLPWCPSLSVKRKKENVRPIFWRNRIKSYVTRTEAWDEFPNGRWGDSRSPAFGELDGYG
VSLKQTKQNALELWGCPNSLNDIYNIFGDLKTNTQSEGPNAVTWGVFPGKEIIQPTIVEA
VSFMAWKDEAFELWNEWAKIYDPDSLSAKLISQIADNWYLINIVHNDFHDGSGIFRIFES
DCVSELVEADR
>A0A8I0QD56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter japonicus|TrEMBL
MAAQTGPLPAISFEFFPAKSEKAAATLLENAKTLSAFGPQFMSVTYGAGGSTRDRTLATL
KDMVRETGAPMAGHLTCVGASKEEVDAVARAYWDAGVKHIVALRGDPPPSAGGVYEPHPE
GYAGAVDLVRGLKEVAPFEISVAAYPETHPAALSPQSDLEHLRAKIDAGADRALTQFFFE
ADTFLRFRDRAAAVGIEQPIVPGILPVGSAAQAWKFAEMCGANVPRWMRDLFDGLDETPQ
TRTLVAATIADRLCQTLRAEGVEQFHFYTLNHADTASALCRLLGRRPL
>A0A1B0DJC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phlebotomus papatasi|TrEMBL
MERSEEKAGNPSEISKGAFGEKKLIEVIQDRARRKELFYSIEVTPSDPPLNLDSLQPPPL
FASITWISDKNLVAFRKDPQFCPALQWMKVLREKLPVLSHLTCLNMTPEDLEGIVEVGDL
KSILALQGGNVSGPAPARFEHAVDLVRWLRQRLPDATIGVAGYPHTHFLALSPLDDLHRL
REKVEAGADFIITQITFSSSDFIGFVRKCRFLKITCPMLPGVFIPPTFESLLFVTKISRI
PVEEELWEKFKNKKDDLEAFQEFSLNEAEKWMKEVLAECPEDVFGFHIFTWK
>A0A2J7ZV84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetrabaena socialis|TrEMBL
MKLIDKVNQKLKEGKTFFSFEFFPPRTEERRPHPNTSDDTQGVENLFERLDRMVTYGPVF
CDITWGAGGTTADVTLDIATRMQNQAGAAPTLDAERAAGVPVVVKVDFEEEHVRLLGDHA
ADLRAPACKRTFGKSARHALHHLRSDYVYGKSYVEFFCSPESWESLRPRLDAAPSLTYLA
TTAAGAPSGNMGPDDVNALSWGVFPGKEVLQPTVVCAASFGVWKEEAFELWLSEWGSLYE
EGSASRGVLSAIAESWVLVSVVDNDYVSGDLFAVLLG
>A0A1H9NMR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas soli|TrEMBL
MSLLKTTLDANAFACILEFVPKPSAERFATLDTLMARTQLCGWPLTVAIGDRVGSALDMS
PLDAFNSLAEPVPALLHFSGKDRERHELLAQLQRMDAAGLDQLLLLTGDRLPGHVPGERP
VRYLESVAALQIVRQARPHWLLAAALNPFKYQEAEGGAQYSKAEKKLAAGADLFILQLGF
DIDKHQEAFDWMQRQPRPKPLMACIMALTEGRAGMLEHVAGVTVTPSMRALLAAEAAVSK
TYAKERANQRLALQVIGLKLMGYAGVHLSGIHEVAQFEALEQTIEVLQPQFSSLRDWAPA
WEAAWQAPGLTPVTFHPPGHAWRLGQRQITASNKEKVRYHLLSAMHHQLFSRTTALSKAF
GWAVTRPLWANPTAAQWLHQLERRIKRPMVGCDTCGSCRLEDTLYICPETCPKGLANGPC
GGTSLDRCEFGDRECVHSAKYRLAVSVGRTEVLRERLIPCVQVENRQRSSWPGWFEGGTS
RSPSLQPDVAPEFNE
>A0A2A5LPT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus lautus|TrEMBL
MKPNLRQAWENQVLVGDGAMGTYLYQKGFPVGISYEELNLTSPEVIGNVHRQYVEAGAQV
IETNTFSANYDKLSKYGLEARVGEINRAGVRIAREAAGDQGYVVGAVGSIRAGKRSNIST
SELKRYFEEQLSVLISEGVDGILLETFYDVDEMQLALAQARMLSDLPVICQFAVEDIART
LDGFTMPDAYRILSHEGADVIGFNCRTGPNGIMRALETLNGIMNLPASVYPNAGIADYVD
GEYRYGASPEYFGKTALEFADRGARIIGGCCGTTPEHIAEISSALSGYVPSPLPAVEEAE
INRIVIHETAQEQFYERSGEPTIVDIVKERHTVIVELDPPRDLDITKFMKGAEALKKAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVVGAAFNP
NVRHLDKAVARLEKKIASGADYVMTQPVYDPELMVRLREATAHLDIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAMGVKIGKELLDVATEHFNGIYLMTPFMFY
EMSVQLMEYVWEKSGRRLTPLFH
>A0A8J6G0R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microtus ochrogaster|TrEMBL
MLGRDFLSLSLNFRLPLVLFPLATRQLRPASSSCAREMAPRPPSRNPAMVNEGSSSGSES
SKDSSRCSTPSLDPERHERLREKMKRRMDSGDKWFSLEFFPPRTAEGAVNLISRFDRMAA
GGPLFLDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHVTCCQQRQEEITGHLHRA
KELGLKNIMALRGDPVGDHWEAEEGGFNCATDLVKHIRSEFGDYFDICVAGYPKGHPEAK
SFEDDLKHLKEKVSAGADFIITQLFFEADTFFSFVKACTEIGISCPILPGIFPIQGYTSL
RQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNR
EVATTEVLKQLGMWTEDPRRPLPWAVSANPKRREEYVRPIFWASRPKSYIYRTQDWDEFP
NGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEKSVFEVFEHYLSGEPNQ
HGYIVTCLPWNDDPLAAETSLMKEELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGG
YVFQKAYLEFFTSPETVEALLLVLKKYELRVNYHIVDVQGKNITNAPELQPNAVTWGIFP
GREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNE
FLLDNCLWQVVEDTFELLNRHATEGDAQTP
>U1WZF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aneurinibacillus aneurinilyticus ATCC 12856|TrEMBL
MVMPQKNLKTYLKDNLLIGDGAMATWLYRLGVPIGVCYEELNLSNPEIISTVHRSYYEAG
ARFIQTNTYGAHRDALSRHGLQTQVQQINRSAVQVARQAVGSDAYVVGGIGSINAGRVRN
TEQMATYGDQYEEQASALLLENVDAILLETFLDVDELLLALDVIRPLTDLPIIAQLATIE
VGRTRDGHTLTRAFAELVKAGADIVGLNCRMGPAEVLRSIEGAVVPGDTPLSVFPNAGRL
AMSDGEYSYASVPQYFGDSALRFRAQGARLIGGCCGTTPEHIRMMAQVLAEREPLPRVNP
EVQMEEEPIPIRVVPPVRPKGIVDTVTQRHTVIVELDPPRDLDTEKFLQGTAELRNAGAD
AITLADNSLATTRMSNLALGSIMKAKLSAEPLLHIACRDRNLIGQQSHLMGLHALGINQV
LVITGDPARFGDLPGASSVFDVSSFDLIRMIKQLNEGYSFSGKPLKQRANFVVGAAFNPH
VRQFDAALRRLEKKVEAGADYIMTQPVYDREIIEQIYEGTKHLNIPIFIGIMPLTSSRNA
EFLHNEVPGIKLSDEARERMRQYEPGEEARHEGVSIARELVDMAMERFKGIYLITPFFYY
QMTAELTRYIRKQSDVKLSIQK
>A0A6D2I0N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microthlaspi erraticum|TrEMBL
MKVVDKIKSVIKEGKTAFSFEFFPPKTEEGVENLFERIDRLVSYGPTFCDITWGAGGTTA
DLTLEIASEMQNVICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQEK
FVQVEGGFDCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFLNDCRQIGINCPIVPGIMPISNYKGLAYGWFLQNQE
MCKKILAHGITTLHLYTLNVDKSATAILMNLGLIDESKVYRSLPWRRPANVFRTKEDVRP
IFWANRPKSYISRTKAWNDFPQERWGDSRSASYGTLSDYQFMRKRSRDKKLQQEWVVPLK
SIQDVQEKFKELCLGSLKSSPWSELNGLQPETKIINEQLGKINSSGFLTINSQPSVNAAK
SDSPAIGWGGPGGYVYQKAYLEFFCSMDNYLGSVPIKEILQPTIVDPASFKVWKDEAFEI
WSRGWANLYPEDDSSRKLLEEVKNSYYLVSLVDNDYINGDIFSSLS
>A0A3T1DI26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas olivaria|TrEMBL
MSSHEHPLGISFEFFPPSTDAGRDKLIRVRDELAARKPRFFSVTYGAGGSTQARTRQVVR
EVSESGISTAPHLSCIGSEKSQLRDLLLQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKIVDNLTD
>A0A562SK00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacibacter cauensis|TrEMBL
MKVTEHIAQAKDTLVSFEILPPLKGKTINSIFDHLDPLMEFKPSWINVTYHRAEQVFKKK
ADGTFEKVEVRKRPGTVGICAALQNHYNLDAVPHLICGGFSKRETEDALIDLNFIGVQNV
LVLRGDAAKNETFFEPHHDGHKYAIDLLKQTINLNHGIYLEEDIRDGFRTDFCAGVAGYP
EKHFETPNQEIEMQRLKDKVDAGAEYIMTQMFFDNSKFFAFVKSCREMGIDVPIIPGLKP
LTSKKQLSVIPRTFHVDIPTELSNEIMRAKTDEDCKRIGTEWLIQQSKELKAFGVPVLHY
YTLGSPKVIYNVVKEVL
>A0A510K8Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia wadei|TrEMBL
MRIKDLFEKKKHLISFEIFPPNKNFSVEKLKDVTDELVQYKPDFISVTYGAGGKTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEINDYLQEAKKCNIKNILALRGDVPQGETEDIYN
RGDYKYASELISDLRKNSEFNDLSIGGAFYPETHYENNDLVDLFYLKNKVEAGTDFLASQ
MFFDNDIFIKFKEQAEKLDIKVPLIAGIMPVTNAKQIKRIIELSKCSVPEKLDKLLGKYG
DNPESMKKAGIMYASEQIIELLAYGIRGIHIYTMNKPEIAKEIVKNIEFAR
>A0A653LK24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 8BK|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARQLAGYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VSFIREETGDQFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADCYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTDSIQAYG
EQVITEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A2H5ZQK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR30|TrEMBL
MRICQLLQRTAPLFSFEFFPPKTAQGEEALFRTIEALRPLEPAFVSVTYGAGGSTREKTL
DWVARIKHEMGIEAMAHLTCVGADRKEIRHILERIAALGIENVLALRGDPPRDQPTFSAV
ANGFAHASELIRFIREEGFDFCLGGAAYPEGHLESPNLETDLLYLREKVNAGADFLITQL
FFDNQLFFRFLERARALGIAVPIIPGIMPITNVNQIERFTQLCGATIPEALRLELDAVRD
DDAAVRTIGIRHAISQCEELLERGVPGIHFYTLNQSPATRAIVQHLRGGR
>L0NHX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhizobium banfieldiae|TrEMBL
MTPTLPPQKSFGLSFEFFPPRSADMEGQLWDAVLDLGAWNPDFVSVTYGAGGSTKAPTLS
VVRRLIRETALSTAAHLTCVDASRDETRSVVEEFRAAGVRRIVALRGDPASGVGTEYRPH
ADGYANAADLVAGLREIGNFDISVSAYPEKHPESADLAFDIEMLKRKADAGAARALTQFF
FDNDVYERYLEKVRAAGIDMPIVPGIMPIQNLTQLKRFAGRCGASVPTFLDSRFEGYDDK
PEDRAKVAADVAAEQIDDLLNLGVTDFHIYTMNRSGLVNQVLEQLGRARRAQADAAA
>A0A1Q8VX67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MHDNEPTGPTAAAGGRAGDLNSAETGTARRLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPADGISSGGYEGSAHESEAGRCQVAPRVRAVQEQTNPSECVLAH
VLESSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRADDVAGELRH
ADDLVRVIREVEADFFGDGRRHVTIAVAAYPATSDHIEAIEVLAAKQAAGADMAITQVFY
DAADYMALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSTLGSASGAT
LVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDA
VDRGYLQATPGRGPSFLRRGSPGAALSSLHPVQPHTTITKENA
>A0A6I7Z5W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus sp. T0101B.F-10|TrEMBL
MSSTLSFEVFPPNTQVGTEKLITTLEELQQLAPDFISVTCSNNRQTIEETTLRVADYIHT
ELQVPTIAHLPAAYLDQAQVQRLVTRLDQIGIHQILALRGDIIPELPPKKDFTYASDLID
YVKQQAPHFHISGACYPETHPESQNRIEDVKNLRRKVAGGCDQLITQLFFDNELFYQFQE
SCDLADIKVPILAGIMPIVNRKQALRLIKTTNTKLPRKFLAILEKYEHDPIALKEAGLAY
AIDQIIDLATQDVAGIHLYTMNNAEVAKHIYYNTKNVLKGQIEVR
>A0A5A9E3B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. CH30_1T|TrEMBL
MKPLLEALKERILIADGAIGTLLYSYGVDRCFEELNLSHPNEVLKVHKEYIDAGADIIQT
NTYGANYQKLSRYGLEDSVKEINTAAVRLARKAAGENTYILGTIGGIRGIKQNVSLEEIK
RSFREQLYCLLLEGVDGILLETYYDFEELTTVLNITKREADIPVIAQVSLHETGVLQNGM
EIKDALQQLELLGADVVGINCRMGPFHMVNSLEVVPLPKRAFLSVYPNASLPNYEEGRFY
YSAEPDYFGDISNELRLQGARIIGGCCGTTPDHIRSVASRLKSREPVKEKVVKAKKVVQL
SSPSIRGNLLHEQVREKKSIIVELDPPKHLDTKLFFQGAEALKEVGIDALTLADNPLASP
RISNDAIGSLVKSKFDLTPLVHITCRDRNLIGLQSHLMGLHTLGIHNILAITGDPAKIGD
FPGAASVYDLSSLELIELIKQNNEGISFSGKSLRECTQFSVGAAFNPNFRHLDASVKRLE
KKKKAGADYFISQPIFGKEQLIQVHEATKYLDVPIFIGIMPLISPRNAEFLHHEVPGINV
PEETRQRMKEAGSDPVVARTVGMEIAKDLLDTAIDLFNGIYLITPFVRYDMSIELIHHIQ
AKTNTEREVPYGHHFV
>A0A6J3M981|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dissoconium aciculare CBS 342.82|TrEMBL
MPHVIEPAVAASSSDKIIDKIAALPPGTNYFSLEFFPPKTQQGFSNLHARLVRMSHSLRP
LFVNVTWGAGGSTASKSLALAELTQHSLGLTTCLHLTCTNMSRKLIDETLDQAKALGVRN
LLALRGDPPRSAEYRDDRVPGQEEDDSNKDFAWAVDLVRYIRSRYGDYFCVGVAGYPEGH
SDQSHPEHQSVDHDLPYLVEKVAAGADFIMTQLFYDVQAYERYVRLLREHDSGLFKTIPI
IPGLMPIQNYQILRRSTKLSHASLPDDILKRVEAVRSDDEAVKAVGVDILSEIVESLKAL
DMADHRGFHFYTLNLEKAVAQILERCDLIPCSISPDASPVGRSSGPEEAIEEETDGFIVV
PDADQRRRRRLSSQTNSQPGNRVVVSREKTKENSNPHIAVFEAPDDEAGVPKEKISSRAN
TLAISEGRGALGREAIWDDFPNGRWGDARSPAYGEIDGYGTSLHVSVPEAKRIWGEPCSA
SDISQLFRRHIEGQIPSMPWSEEALQPETLSIKAELLSLIDRGWWTVASQPAVNGVPSTD
ATHGWGPRNGFVFQKPFVEFFVPAGDWATLQERFLAHPQITYFAGNDRGDFSSNHPDSVN
PVTWGCFAGKEIITPTIVEAVSFRAWLEEAFGIFLEWQRVYAPGSPSSKLLESVRRGYWL
VNVIHHGYLEQGALWEDLLK
>A0A1F8ZM81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium GWF2_42_12|TrEMBL
MQTLKESLSSKKFTITAEICPPKGTDTSDFLKKAQLLKGKIAAANVTDNQRAVMRLSSLA
CSVILLKEGIDPVFQMTCRDRNRIALQSDIMGASVLGIKNILALSGDHVSFGDHREAKPV
FDLDSVQLVQVIDKLNKGTNMKDMPLKGGTDFFIGAVVAPEADPVEPEMIKFEKKVEAGA
RFFQTQAIYNMEKFHRFYEYAKRFGVKILGGILLLKSAKMANFLNTNVPGVKVPKHLIDE
LEKAQDQLEKGIEIAARQVNELRSFCDGAHIMAIGQEESVVRIIEGAVL
>A0A420WAS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanibaculum indicum|TrEMBL
MSGNLSFEFFPPKTEAMEESLWRAIQRLALLRPNFVSVTYGAGGSTRERTHATVARLLAE
TDLVPASHLTCVNASRDELDAVARSYWDIGVRHIVALRGDAPGDTPGSLGPYTPRADGYA
YASDLVAGLRRIADFEISVAAYPERHPESTSLQADLDNLKRKIDAGATRAITQFFFEADT
YCRFLENARKAGITVPIVPGILPVTNFGQVCKFAKACGAAVPAWMGGLFEGLDNEPDTRQ
LVAATVAVKLCEKLRENGVEDFHFYTLNRAELTLAICRVLGLGARTVAPAPVA
>A0A380WKV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter aminovorans|TrEMBL
MTPPRPRQPDEHPDGIDLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPHDFRPVHLGKKIAAGAQFVQSQYCFDVPMFRTFMNRVRDLGYDEKCF
ILVGVGPLASAKTAKWIRANVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPG
VSGVHVMAYRQEEYVAEIVDESGVLKGRRPWKREARADDQRVAERLEHILHDDVTESQVD
MVKTAH
>A0A1B1Q100|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecochloris sp. CIB 2401|TrEMBL
MLVKDILTSATSPAFSFEFFPPKKDQDWDALFQTISQLIPCNPSYVSVTYGAGGSTRERT
HDLVIRIQKETGLTVVSHLTCIGSEKQEIHDILSTYQEHGIDNVLALRGDLPKGMSSYAE
ATRDFEHAIDLVRFIRKEFPSMGIGVAGFPEGHPQTPNRMTELNYLREKVDAGADYIVTQ
LFFDNRDYFDFVERCELEGITIPIIPGIMPVGTKKGLVRMSELALGARVPAPLLRKVMEA
PDDKAVAEIGIEWAAGQVEELLAADIKGIHFYTLNHAEAAREILVRRCGMAAS
>A0A2D9NSH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MTYGPCGGVNPDGSCEVHTDPCVFLDRPLPVPVEDAASATRPPPTAAAGEIADILARRPL
IMTGFPARPLTAEDVSRVADVLAPNTDAALSGDAATSRTQFPPSYRGHLMTAAGVRAWIG
VNTRDRNRVALEGELAALCHAGVAGVHCVTGDHTDTGDRPDAAPVFDLESTTLLPRAREV
GLVASFAESPCAPPRESRGVRVAYKQRAGGRMCLTQYCGGVEDVAAFVEACHRAGATVPV
LPGVPAIVDEDGAALLASFHAASLPPGYAERLRGARDMRAEGVRLAIEYGSALLEVPGVA
GVVVAGGARRGDEIAYAGSLATIARELGGGS
>A0A080MDG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter sp. SK-02|TrEMBL
MTPQPPVFSLELFPPQTLEGAEKLRGTRARLALLEPRFFSVTFGAGGSTRDRTLETVLEI
QREGHQAAPHLSCIGSTPDSIRSILEQYQAHGIRHLVALRGDLPSGMARPGTFRYANELV
EFIRAETGDWFHIEVAAYPEYHPQAKSPMEDLLAFKRKLDAGANSAITQYFYNFDAYAHF
IDECQALGIDVPIVPGIMPISSYSSLARFSDNCGAEIPRWVRKKLESYGDDTLSIHAFGL
DVVSSLCAKLLASGAPGLHFYTLNQVELTTTLWQRLGLSRRY
>A0A448EH89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella baltica|TrEMBL
MAFHHAQHSQSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPTGSPKPTRFAADLVRLLCSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPNWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A553I7K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylaria flabelliformis|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTGMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
AIKSLELAEICQRELNLTTCLHLTCTNMSRKMIDSALEDAKALGIRNILALRGDPPRASE
YQDPNEDPENAIDEGFVWAIDLVKYIKNKYDDYFCIGVATYPEGHADESHPLGQSLEHDL
PYLVDKTLAGADFLMTQLFFDTDAYDKFERRLREHPSGAFKTIPIIPGIMPIQSYQMIKR
TTKLSHARIPDDIMTRLDAVKKDDEKVKNVGVDILCEIIERIKEIKNRTPGPRGFHFYTL
NLEKAVSFIVERTHLISSPAEEEEAIVDDGPLPNIPGLVINGASPVEGHFPDSGHSRRQS
TVGSEPRNRVIVSERTLSNPEYEASQADAGIKAGAINSRANTLAISEGEGVLGREATWDD
FPNGRWGDARSPAYGEIDGYGPTLHMTQAQAISLWGHPKSREDVNTLFVRHLKGELTAIP
WSEEEVHEETGTITDQLIQLNQRGMWTVASQPAVNGVRSEDPTFGWGPRNGFIFQKSFIE
FFLSAAAWKSLHEKLTSPEIRGMVTYYAANAAGDFESSDISGGVSPPQPTETIDESDEGY
VTGESSTNAVTWGVFPGKEIVTPTIIEEVSFRAWAEEAFGIFSEWAQVYGKGHESEKLLE
ATRADCWLVNIIHHDYMTKEALWDLLLK
>A0A1V6SG17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium flavigenum|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPVEKVDQALQAAYKAGCTNILALRGDPPREKEA
WEAAENGFCYAKDLVKYIREKYGNHFDIGVGGYPEGADDNTDVDQLIDHLKEKVDAGSSF
VVTQMFYDADNFIEWVKKCRAKGINIPIIPGIMPIQTYASFIRRSNWTKVKVPSEWMEAL
EPVKNDDSAVRDIGKTLIANMCRQLIAAGIKHLHFYTMNLAQATQLVLKELELTPSEDSP
IQRPLPWRPSLGLGRRSEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISDIFVNFLTGKLDRLPWSDSPITTEAHEIQEDLLK
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEEND
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCHDAASPSRQLIQHVMDDWYLVNIVDNDFHRSNAVFELFNGLEIKDLNVEVTGKPLTNG
HAEPNGVAAN
>A0A1G7V7A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klenkia brasiliensis|TrEMBL
MTGTVRELLQQGQPTWSFEFFPPKSPAGEEQLWTALRELERLAPSFVSVTYGAGGSTREG
TLAVTERIATDTTMLPLAHLTAVDHSVAELRNVVARLAAAGVTNVMALRGDPPGADPQAD
WTAHPEGLSYAAELVELVRGMGEFCVGVAAFPETHPRSPDPETDADMFVAKCRAGADFAI
TQMFFQVEDYLRLRDRVSARGCDVPLLAGVMPVTSPRQIARIVQLSGQAFPAPLAERFEA
VVDASPEVQRELGVDVATEMCAQLLAEGVPGIHFITMNRSTATREVYGRLSPVSAASAS
>A0A8B5X6Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Competibacteraceae bacterium|TrEMBL
MKARFLSSLHERPLVFDGGMGTLLYTQGVFVNVCYDELCRTQPDLVLKLHQAYVVAGVDV
IETNSFGANRYKLQPYGLAADVAPINRAAAELARRAVGPEGLVAGSVGPLFTPGEVTESE
PIPTADVAAAFGEQIEALVDGGVDVILLETFTDIDHLIQAAAAARRSGCPVIASFTLRGR
AQSASGPDAPEVVYTRKLNDCPDVDVIGLNCGVGPAGMLERLRNVMPVAQKPVLVMPNAG
GPSEVGGRMLYFNSPEYFTEYAKRYIELGARAIGGCCGTTPDDMRCAARALSGLSGVRRH
LEIHVAGDRQDAPPLPDPVPLAQKSAFGAALAAGRRVTSVELLPPRQVDRLEGFIEAGRQ
CREAGVDAINIPDGPRACARLSVLVAAMTLEREAGIEAIPHLCCRDRNLIALQSDLLGAV
SLGLRNWLLITGDPPKLGDYPDATGVFDIDAIGLCRLVNNLNRGCDAVGKAIGPPAGLVL
GVGANPVAIDIDREVDRFAAKIDAGAEFAITQPVFDPDALLRFLDRVNRFPRTIPILAGL
YPLISLRNAEFMNAHVPGVDVPQAILKRMAVCRDRAEGIAAGIEIARDMQTRIADAVAGI
QVSAPLGKLEIALAVLA
>A0A1J5S3D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MIKNTKISFEFFPPKTAEGMQKLRDTRAKLAKFKPEFFSVTFGAGGSTRDRTMNTVLEIQ
AEGFGAAPHISCISSSKEEIRDLLQAYQAHEINRLVALRGDIPSGEVSAGDFRYAAELVE
FIRAETGEYFHIEVAAYPEFHPEARTPAADLLNLKHKMDAGANSAITQYFYNTDAYFRFM
DQCSAAGINIPIIPGVMPIYNITQLARFSSVCGAEIPRWLKMRLEEYGDDIASLRAFGLD
VVSELCETLQASGVQSLHFYTLNQAGVISNILENIGY
>A0A6L2QAT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coptotermes formosanus|TrEMBL
MRETVLQIFGNEKDLWFSIKPLITGSRQPKASLEEQIHARTDSGDKFCSFEISPPKSELD
TCQLLRRLHSLYNICSPLFTAVTWHLDASMSASVYMQILAGNHRALRLAAAIGNINSVLL
HLSCVGLTKRQVLQVLWCASDVGIRNIFALHGDRPAKINKFIFSSGFRYATDLVSFMHEK
FGDYFTICVAGYPLGHPDGVSFEQDLLHLKEKVDVGASFIITQFFFEVSTFVNFVQWCRR
IGITVPIIPGIMLIQDYPSLMHISRVCSVKVPKEVLDIIEPIKDNHEAVRKFGVHLAVQM
VSHIFSYNYSCGAHFFTLNR
>A0A849A6B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nakamurella aerolata|TrEMBL
MLTVRDRLAAPGRKFSLEFMPPRTAEEDPTLWRAVDRLKQLRPAFVSVTYGQGGSRRGKT
AEVVGRIIADTDLTAVAHLVTVGHSAAELRATIDGFADAGVRDILALRGDPPGDPLGEWT
KHPHGFSYAAELVELIKSMGDFSVGVAAFPEKHPRSPDLETDTRFYVDKVRAGADYGITQ
MLFSAESYLRLRDRVQAAGADVPLIPGIMPVLSFPRLIRICELSGQAIPVQLAERLSAVG
DDASAARAIGIDHAVEMAETLLDNDVPTLHFYTHNRANAVIDVLDRLGMNNPVPTVQT
>A0A7C6YEP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MTIRPHSDPVSGGRHPSIVDRIAAATTPRVPFSVEFYPPRDEAAEDRLWRAAEVFSELGA
AFVSVTYGAGGSTRDRTVRVVERVVRETDLVPIAHLTAVGHPVSELREMIESYGRAGVTN
ILALRGDPPGDPLGEWTPHPEGLLYAEQLVRLIHEVGDFHVGVASFPEGHYRARDLDHDT
DVLVSKLRAGAEYSITQMFWDVEDYLRLRDRVAAADAEQGAKPVIPGLMPVTSLRQVRRM
VELSGCALPDDLATRLQTAAGDGPEENRAAVREVGIEFATQLCERLIAEGAPCLHFNTLN
FSRATQEVLANLSMAPAPGVAGGAVLN
>A0A7Y2NTV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boseongicola sp|TrEMBL
MSEPTVSFEFFPPKSLDASFQLWEALRSLRHLDPAFVSVTYGAGGTTRELTHEAVETIRD
HTGVEVAAHLTCVNASKDETLEIAQRYAAAGVSKIVALRGDPPDGSEAFEAHGDGFASSV
ELIEALASVGTFDIIVGAYPDPHPEAGYE
>W6RC37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium favelukesii|TrEMBL
MSSRSSTFIRVIKAGRGSPSPSGLRATPGVSWPPQRAKAPNPYLPGDNDMALNSDARRKI
GISFEFFPPKSEEMEGQLWNAVSELQDWDPDFVSVTYGAGGTTKAPTLATVSRFLAETPL
ATASHLTCVGATKDETHSVIETFRKVGVKHFVALRGDAPGGVGAPYQPHPGGYANAAALV
AGLREIGDFEISVSAYPEKHPESRDTAADIDMLKQKADNGATRALTQFFFDNDSFERYLE
KVRAAGINIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDDKPEERAKVAADV
AAEQIEDLARRGLTDFHLYTMNRAPLVSAVLTHLGFTREGAKKAGAAA
>A0A484HL70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacteraceae bacterium|TrEMBL
MKMKTPSKLEKILAAGHQAVTSECGPPRGSDPKEIIEKAKLIQKHVDAINITDNQTSMTR
LCSLAACVHLKLMGLEPVLQMVTRDRNRIALQSDILGAASFGIHNILCLSGDHQSFGDCA
QGQNVHDLDSMQLIQTVRRMRDEGKFLGGDDIHTPPGMFVGAAANPFADPFDIRVPRLAK
KIAAGAEFIQTQCIYNLDKFEKWLSLARDRGLHEKVFIMAGLTPMKSAGMARYMKNRVPG
MDVPDDLVKRLADTPKEKQAQEGIDICVESIERIKEMEGVSGFHIMAIEWEEKVPEIVER
AGLFPRPEIN
>A0A1W1HKV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfamplus magnetovallimortis|TrEMBL
MNLKESLEKKKFVVTSEIQAPMGDDNPEELVESLKKIRGRVDGVAISDVELEGVVGDSIQ
TCDLLNKNRFNAIYQTTTRDKNRFQLQKDLTQAHETGVENLLVFTEDYRISGDSLQESMF
FHVDSGKLASVLEHMKRGETIDGHALEKKIEFVLGSGVETPWGKNVPKKGMEEMEQMVEV
GTGYFLTTPIFDVDQFEKFMKQVNTFGVPVIAEVMILRTAGMGKFLNRHFKSGLVPDWAI
QKLLKAPDKTKASIELFAETVNNLKNLCQGIHIITIGGEDKLAQYLNAAKLK
>A0A1X9YKD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. KC8|TrEMBL
MSVSIAQMEEARRALDAPLFADLAGDCQVSFEFFPPKTAKMEETLWSAIETLAPLGPRFV
SVTYGAGGSTRERTHATVARIARETSIPAAAHLTCVDASRDEILDVAREYWAAGVRHIVA
LRGDPPREGEAFQPHPDGFENAAALVAGLKSVAPFEISVAAYPECHPDSVDVAADLDNLK
RKIDAGANRAISQFFFSPEAFFRFRDAVAAAGIDAEIVPGILPVSNVAQTRKFAAMCGAA
IPPWMDRLFEGLDDRPAARQLVAATIAAEMCRKLYAGGVRHFHFYTLNRAELSYAICHLL
GLRPTSQSREKAA
>A0A4R0XEJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia steynii|TrEMBL
MNPIELSFEFFPPKTQEGLDKLRATRAELLPLKPKFVSVTFGAGGSTQQGTLDTVLDMAK
DGLEAAPHLSCIGSSRESLRAILNEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFRIEVAGYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DAHKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VADLCRRLVEAKVPGLHFYTLNGAAATKAICERLAG
>A0A0W1D7B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. H115|TrEMBL
MTSNLNSLAEARRAAASPLFANLEGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLAPSFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASRAEIDEVARAYWEAGVRHIVA
LRGDVPGGEPYRPHPEGYANAIELVAGLKAIAPFDISVAAYPETHPDADCPQADLDNLKR
KLDAGATRAITQFFFSPDSFLRFRDAAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMVSLFDGLDDHPGARQLVAATVAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVSTAKDQAA
>A0A0E1PQ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii NCGM 237|TrEMBL
MNRLPFFLKMFRCLQGFDMTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITY
GAGGSTRERTLAAIEDFNGKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDL
PSGQVGLGELPYAQDLVRFIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGA
NAGITQFFFNPDSYFYFIERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRK
QLQAYGDDSESIKAFGHEVVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A2Z6TUL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia vietnamiensis|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTPQGTLDTVPDMQK
DGLEAAPHLSCIGPSRDSLRPILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPAADLQTFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTGLCPRLIDAGGPGLDFYTLNAAAATRTICERLTM
>A0A0J8GWW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catenovulum maritimum|TrEMBL
MNISFEVVPRTEEATQQQIEFVKQNLPFVNTINIPDLLRLPIRSWDGTDYVDQNQFNFIP
HVRSIDFDLKSNKLQQIIEARELSKILLVTGDPPPDRNHQIYNTDVVDLVRKIRGDFPDI
EIYCGFDPYRQGVKQEKDYINKKFDAGCDFILSQPFFDMRLLEVYSDFLPAEKVYWGVSP
VITEKSQSYWESVNHVAFPKSFKPDYEWNVQFALDVLEHCKKTGSHCYFMPIRIDLDKYF
LPIKNSFTA
>A0A3D3CEW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistaceae bacterium|TrEMBL
RAIDGLKGLAPDFISVTYGAAGSSRDRTVEIASAVHNRWGFTALAHLTCMGSTPPEVEKV
LEDLEQEGITNVLALRGDPRPEGIPADSPFRYASDLIRHVRRGHFRDFSLGAAAYPEGHP
QSPTIEEDILNLKRKQDEGADFLITQLFFDNEAFFRFMDKVRGVGVTLPVLAGIMPVLNA
RQIGRIVSLCGASIPPKFARIISRYEETPDALAEAGIAYATEQIVDLLSWGIDGIHLYTM
NRPDVAARIMGSISTLRSTLVAGQTAPTEG
>A0A3C0C684|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistaceae bacterium|TrEMBL
MRDYFEQERPTMTFEIFPPKGAGDLASIFATVDALASLAPDLISVTYGAGGTSRVNTVEI
ASQIQNSYAIPALAHLTCAGNSIEEVEPILKTLSENGVKNILALRGDLAESETLKDFRYA
SDLIRYIRSRYDFRIFAACYPEKHIEAYSMEDDLRCLKEKADCGVDVLISQLFFDNEIFY
SFRDRARTIGIATPIVAGIMPITSSSQISRMVSMCGATVPEKVQKIIRAFGHNSMAMKEA
GIAYATAQIVDLLAAGVDGIHLYTMNQPDIAKRISENIRGILYSLRVKRG
>A0A7W3NMC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces murinus|TrEMBL
MALGTASTRTDRARTVRDMLAGGKTTYSFEFSAPKTPKGERNLWTALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVAHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVEAGCDTPVIPEILPVTSVRMLERLPKLSNAQF
PDALKERILAAKDDPAAVRSIGIDFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHHPPQA
>A0A5M8S0V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus swezeyi|TrEMBL
MGLFEDIKSKILIADGAMGTLLYSYGIDRCFEELNISKPDEVKRIHEAYVQAGADIIQTN
TYGANFIKLSRYGLEDETKQINEKAVRIARSAAGSAHVLGTLGGIRTFNKNAYSLEDIKR
SFREQLYLLLNEQPDGLLLETYYDLEEAREVLKIARKETELPIVLNVSMHEEGVLQDGTP
LSEGLKLLADLGADVVGINCRLGPYHMINALEEVPLLEDAYLSVYPNSSLPSLVEGRLVY
ETDDQYFRDSAMEFRNQGARIIGGCCGTTPNHIRAMAEAVKGLPPVTEKHVKTRKKAAAA
VRHERTEPALDDLAKEKRSIIVELDPPKQLNFEKFLRAAQELKSAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRIE
KKIDCGADYFISQPVYSEEQLIKIHEETKHLKTPIYIGVMPLTSSRNAEFIHNEIPGIKL
SDAIREKMALAGTDKQKQAEEGLAIARSLLDTACDLFNGIYLITPFLRSDLTAELTAYIH
KKEKETTNA
>A0A2A3F4E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. ACS1|TrEMBL
MTFDSVRGRASEGWVTRTPSIVDRIRSSGDGRVPFSVEFSPPRDEAAEARLWRAVREFER
MGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWEKHPQGVEYAEELVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVTAYDPEQGAKPIIPEIMPITSLGSV
RRMLELSGSRLPAHLEKRLATAAGDGPEENRAAVREIGIDLATEMSERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSGVADPAPVTPAPVS
>A0A0L8JDI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces viridochromogenes|TrEMBL
MALGTASVRSDRARTVREILASGGTSYSFEFFAPRTEKGEQTLWNTMRRVEAVGPSFVSV
TYGAGGSTRGGTVKATQKIASDSTLTPVAHLTAVDHSVAELRNILGQYADAGIRNMLAVR
GDPPGDPLGEWVEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVVKAGCETPIIPEVMPVVNVRTLDRLPQLSNAAF
PADVKDRILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQQS
>A0A482ZU52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured SUP05 cluster bacterium|TrEMBL
MVEFIKIKYGSHFHIEVAAYPEKHPQAKNIQTDLTHFSNKVKTGADGAITQYFYNADAYF
RFKDEAEKLGITIPITPGIMPITNYTQLSRFSDMCGAEIPKWILERLKYYENDLESLNKF
GVEVVSDLCQTLKSQGVDSFHFYSMNRAQPSLQIAETLV
>G5ZXV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster alpha proteobacterium HIMB100|TrEMBL
MPVSWSSEHTSYRDKGEENMAVSIDDLAKAGQDWSIEVTPTGATKIDSFAACLPEGTTVN
VTFLPGTDPLDTIAVARRLADDGMNAVPHIAARSLKDADQLDDLVSKMTSQANVSEVLVI
GGGVDKPVGVFDSSMQVLQTGILQKYGITRIGVSGHPEGSPDIPDDALASAIAWKNDFAA
KEGLSLYMETQFCFDAETVLTWERQIRSEGNRLPIRIGIPGPATIKTLFRFAQISGIGPS
MRFVAKQARNVAKLMTVQAPDQLLAGLAEGMAADEDCLLNHFHYYPFGGFAKTAAYGQAV
ATGQIELTKKGGFDVRQAS
>A0A238ZRV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces glauciniger|TrEMBL
MALGTASTRTDHAVTIRELLASGERSYSFEFMAPRTEKGERTLWNAIRRIEAVGPTFVSV
TYGAGGKSREGTVRATERIASDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLALR
GDPPGDPMGEWLRHPEGVDYAYELVRLIKESGDFCVGVAAFTEMHPRSADWESDTRHFVE
KCRAGADYAITQMFFNAEDYLRLRDRVGKAGCETPIIPEIMPVTNVRQIERFAQLGNAPF
PQELADRILAVKDDPAAVRAIGVEYATEMCRRLMAEDIPGLHFITLNHSTASLEIYENLG
LHQRS
>A0A3E2CEY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium VN003|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VSYIRSKRPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGVNVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNADCLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A842IQT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella flava|TrEMBL
MKVTEHIKNANGKTQFSFEILPPLKGQHIQSIFGNIDPLMEFKPPFIDVTYHREEYVFKE
VENGLLKKQVVKKRPGTVGICAAIQNKYGVDAIPHILCGGFSKEDTENFLIDLDFLGIDN
VMALRGDAVKSETYFKPEKDGHAYANELVAQIEDLNKGIYLDEELLNSSKTDFCIGVGAY
PEKHMEAPSLDSDIHFLKKKIKNGATYIVTQMFFDNQKYFDFVKKCRSEGITVPIIPGLK
PIATKKQLNIIPHRFHVDLPEDLIIAIVKCKDNKQVREVGIEWCIEQSKALQKAGIPVLH
YYSMGKSDNIRAIASALF
>A0A842P3A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilus sp|TrEMBL
MTIRYEANPPKILPDVNTDESIIKFIEKMKIISKKCDAIHITENVLGYERVSPIKIGKII
KKEIPNIPITVSLRVRDKTEKEIIKFVDTCVSIGFTGILILMGDPSQSGAPDSGQVSSSV
VSMLKEKGYSTKIEIYLSISNKPNFSKIGKKIKANPKGFMTQVVQNIEQVKNLANNLKKF
LIIPIILFPSEKNQKAADFLRLNLSEYGKEFDKFVKEAHRITGDVLITSPNDFKGLNEYL
KNNF
>A0A7V5WH35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLERVLTSGKFAVTGELGPPKNSDPEVVRKKARLLKGCVDAVNITDCQTAIVRMS
SIGAGIIARSEGLEPVIQMTCRDRNRIGMQSDLLAASAHGLKNLLCLTGDHQKFGNHPGA
KGVFDMDSIQMLGMVRDMRDGKKFQCGEEIKGSAPRFFIGAAANPFAYPFEYRAVRLGKK
IANGADFVQTQIIYNVDKFARFMEMVRDLGLDKKAYILAGITPPKSVGMAMYMKNNVPGM
DVTDEVIGRLKGAKNKQQEGINIAVDIINRVREIKGVAGIHVMAIEWEEAVEQIVEKAGL
LPRPAFAGTQPEAAPAPAAETLTVRSDPGTAVTEAKAEAERILAAARSEAEAIRRETSAA
RGAEVSVQPTVTVAVATDDAGEHEMNETERRMALESVKQGLDALKKAYGLNDDQFAALQK
FIDAEAILKKEPPGEAAAQTIPAAAAPSAPKVGEQARFETKVKAEAEAKAKAEAEAERKA
REEAAAKAKAEAEKKAREEAAAKA
>A0A7X1LAA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSTLEKILTAGHFAFTGELGPPRGSNIEAIKKKAAPLKGMVDSVNITDNQTAVVRMS
SWAASLFAISEGLEPNYQMVCRDRNRLAMQGDILGAYAHGIRNMLCLSGDHQQFGDHPQS
KGVFDIDSTQLIQMVKNMRDEGTFLNGQEIDDAPKMFIGAAANPFAEPFEWRIFRLAKKI
QAGADFIQTQCVFNMEKMREWIKRANDMGLTEKTYILAGVTPMKSLGMARYMKAKVPGMD
VPDNIIDRLKGVDKKKQSDEGIKIACEQIEEFKEMKGVAGVHLMAIEWEHKVPEIAERAG
VLPRPQV
>A0A7X1H319|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKLKEALKRKNFVVTSEVQAPMGQEPEELVENLKLVRGRVDGVSLSESEFEGVVGDTIKT
CEILKENRFESIYQTTTRDKNRLQLQKDLLDAHDAGIDNLLVFTEDYRITGDSLQEMMFF
HVDAGKLNSVLEHIREGRTVEGQELKAKADFLLGSGVESSWGKNVPDLEMKEMEEMTKIG
TGYFLTTPIFDLDSFEKFLSRTNTFGVPVIAEVMILRTAGMARFLNRHLKSGLVPEWMIQ
KLSKAPDKDKASIELFADIVKGLKDLCQGVHIITIGGEEKLRHYLDAAELK
>A0A831QKZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKPDFVEYLKDHVVLGDGALGSYLYEKGIERGRNLDLLNLQAADFVFSAHEEYIRAGSQL
IETNTFGANHFRLREVGAQHRVGEINRAGAGIAVKAAGHQVYVAGSVGPTGLTFPLDEDE
VREEDIRQAFNEQIAALVEGGVDLIMLETFPCLDEILPAIAAARAVAPHLPLVAQMVFPA
RGMTVRGEDALTCGRAMAAAGADVVGTNCGRGIDAMATAVRRLAPLAKEGVILSAFPNAG
MPEMVGHRMIYPAQPAYMAMRSGEMIRYGVHLLGGCCGTGPEHIHEFRSTLKIRPVRIPG
GRLVVAPDKTPETAVAVRTGGFLAGLQTNRLPIIVELDPPTHLDVAPVLAGARALTEAGV
DAISLGDNPLATLRVGNLGVASLMRKETGIQTIIHQSGRDLNALALQARMMEAHLLGIEA
VLAVSGDSASATDQPEVSGVFDLRSYGLLRMLRQLNGGLNMAGRSIKHKTNFSVGAAFSF
RPDNPQLQISRLEKKFELGARFAMTQPLFSREAVERMMDKTSHLDMLIFPGIFPIISARN
AEFLHNEVPGMSVPAEFRRQLASYPGVPDQRKAALDYTRQLVEDIAPIVDGFYFVSPLNK
WDIALEFVRQVRQAGWQGSGRATP
>A0A523VA20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLERLLEKGEFVITGELGPPKGTDVKVVKEKAAMLKGNVDAVNITDNQTAIVRMS
SIATSKILIDEGLEPTMQMVARDRNRLAMMSDLFGANALGIRNMLCLSGDHQSFGNHPEA
KNVFDIDSIQMIHMVKTMRDEHKVICGDEIEGDFKMFIGAASNPFADPFQYRVHRLAKKV
EAGLDFVQTQCIYDMKRFKEFMKEVVDLGLHERCKILAGVTPLKSVGMARYMAANVSGII
IPEDMIERLKGAGKGNVAAEGIKIVCEQIQELRALEGIAGVHLMAIEWEHRVHEIVEMAG
LLPRPKG
>A0A2A3ZJM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MEASTATNVLDDFSLEMTGKDVPGLQQAAHAIPQGTRVNITFLGNENLEMRLEAAKEVLE
LGFVPVPHISARRLKSETELREFLDALQQAGASDHVFVVGGDPATPEGPYPDSLSVIRTG
ILQEYGVAEVGIAGYPEGHPDISTQTLWEHMSAKSASLTEQGLGQVVLTQFAFDAEAVVA
WVHEVRGHGVEADIRIGTPGPAGIKRLLGYARRFGVGTSAGIAKKYGFSLTNLLGTAGPD
RFLTDLSSYESITSATSGVKTHFYTFGGLAATAEWVQDFTTQA
>A0A4R6S793|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium saccharolyticum|TrEMBL
MKIKNIFDEKEVVFSLEVFPPRPDVPIENIYQTLEELKDIDPDYISVTYGAGGGIRKNRT
CELTSIIKEKYDVEALAHLTCINSDQDTLNKILARLEAKEIDNILALRGDKPVDGEPLGD
YNYAYQLIEHIKKHNDFGVAAACYPEGHLETESLDQDIEYLKQKVDYGVDYLISQMFFDN
SLFYKFRSKAEKKGINVPIEAGIMPVINKKQVGRIIELSDAYFPEKFQKILDKYEDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKVD
>A0A3A4X730|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSDNGYKSGSNLEKVLKAGHFAFTGECGPPKGANVEHLKEKMEHLRGMVDAINVTDNQTA
VVRMSSKAASALMVQAGLEPNFQMVCRDRNRIAMQSDILGISALGIRNMLCLSGDHQSFG
NHPEAKNVYDIDSMQLIALVKKMRDEGKFLNDEEIDMPPKVFIGAASNPFGDPVDYRVYR
LANKIDAGADFIQTQCIYNMPRFREFMKRAVDMGLTERAFILAGVTPMKSAGMAKYMAKS
VPGMDVPPELIKRIEGAGKGKMAEEGIKFAIEQIQEFKEMKGVAGVHLMAIEWEHKVPEI
AERAGVLPRPKIE
>M1PT18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocapsa sulfexigens (strain DSM 10523 / SB164P1)|TrEMBL
MLVKDLLQSHKTTFSFEFFPPKEDAAADRLLQTISNLMPLGPSYVSVTYGAGGTTRDRTH
DLVVRIKEQTNITVVSHLTCVGSTRAEIHGILEKYQDAGIENILALHGDPPKDQKNFVEP
VDGFAYAADLVGYIKKHFPQMCVGVAGFPEGHPATPNRLQEIQYLKEKVDAGADYIVTQL
FFDNRDFYDYCERCELAGIHVPNIAGIMPVSTKSGLIRTAELAGGARIPARLLKAVDRAE
NDEYVEKVGIHWATEQIRDLLDNDVRGIQFFTLNSSQATQEIYNSLGVRDSNQLR
>A0A3A4SSJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKLKEALKRKNFVVTSEVQAPMGQDPQELVESLKSVRGRVDGVSLSENEFEGVVGDTIKT
CEVLKENRFESIYQTTTRDKNRLQLQKDLLDAHDAGIDNLLVFTEDYRITGDSLQEMMFF
HVDAGKLNSVLEHIQQGRTVEGQELRESAEFLIGSGVESGWGKNVPDLAMKEMEEMTRIG
TGYFLTTPIFDLERFEKFLSRTQTFGVPVIAEVMILRTAGMARFLNRHLKSGLVPEWMIQ
KLTKAVDKEKASIELFADTVKGLKHLCQGVHIITIGGEEKLKNYLDAAELK
>A0A2A3X4F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MSQEVLASLLKSARYEILPTAGVVDRVHEYVVPGRVITVTASTGLTLEATLSTAEQLQAL
GFTAVPHIAARMVQGRTELEEIVDRLTQAGIDRIFVPAGDATPPAGGYAGALDLIIDLAS
MAAPIQHLGVSAYPETHPLIPDDVTVQAMWDKRDYATHLVSNLCFDPGTIATWLARVRAR
GIDLPLILGIAGKVELAKLARVATKIGVGESTRFLRKNTVTFTKMAKPGGYNPRKFLDKL
APVLDNPSMGVAGLHIYTFNQIKDTEIWRRRQLAALGHNDEVPSTS
>A0A3A4S6C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSLKTESKLEKILASGNLAVTSECGPPRGSDPEAITEKANLIKDHVDAINITDNQTSVTR
MCSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAASFDIHNMLCLSGDHQSFGDCA
SGQNVHDLDSMQLIQTVRRMRDEGKFIGGDEIKRPPKMFVGAAANPFADPFEIRVARLAK
KVAAGAEFIQTQCIYNLDKFEKWMKGVRDRGLHEKVHILAGVTPFKSAGMARYMKNRVPG
MDVPDAVVKRMADTPKEKQAQEGINICVESIQRLKEIDGVHGFHVMAIEWEEKVPEIVER
AGLFPRPVI
>A0A3A4RPI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSELKSGSNLEKVLKAGHFAFTGECGPPRGANIDHLKEKYEPLKGMVDAVNVTDNQTAVV
RMSSMAASALLVQAGLEPNYQMVCRDRNRLAMMSDILGAYSLGIRNMLCLSGDHQKFGDH
PQSKNVYDIDSMQLISMVKKMRDEGKFLNEDEIDVPPKMFIGAASNPFGDPFEFRIYRLA
NKIAAGADFIQTQCIYNMPKFREFIKKAVDMGLTEKCFLLAGVTPMKSVGMAKYMKSRVP
GMDVPDEIIKRLQGVDKKEVADEGIRIACEQIEEFKEMKGVAGVHLMAIEWEHRVPEIAE
RAGVLPRPVI
>A0A3A5B2S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MTEKETDFKARLRSGEQVLVVEITPPKGGDPVPLRFTAKRFHGRVHAIGVSDNRHGICMS
SLAAGAVLAAEGMEPIVHVVTRDRNRIALIADCLGAQALGLRNILCTSGTHQTLSICPAA
RNVFDMDSTQLIEAVAHLGSNGSTFMGERFESAGPFCLGAVAAPFADPVELQLMRLRKKV
NAGASFLITQPVHDLDRFRVWWDQITQRSIHEKSAVLAGIQPLLGAASAKTYAESRPSPR
VPRSLLDRISAAGSPEAERAAGIDIAVETIREISSLKGLAGFQICADRDEGAVLEIIERS
GLGVR
>A0A3A4X607|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSLRKRLASGDFVVLAEMDTPKGVDISELITNARRIKSRVDAVTVPDMDNGVMRMSAIGG
AALMQQQGIEAVMHVCGRDRNRMSLQGDLLAANVLGVENFLVVRGEPMANSDHRDAKPVD
DLDEVSLLGAIRSLREGVDMAGFELKGAPRLFAGGTISLCPDDKTTETEMESARRKIEAG
AEFLVAPAIFDIDHLERFLSGFSNLGVPILATVFLLKSVGIARYISINEPGARVSERLIR
RIRRASDRDSECLRIAGETIASLKGMVQGVKIETVGWEHRLPVILDMAGL
>A0A150HZA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter venetianus|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELKLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIKRFVEKVQAGANAGITQFFFNPDAYFYFI
ERLAKAGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A3A4WCB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MHLERKLEEGHFAVLAEMEPPKGCDPSKLVSDSRRVKGEVDAFVLPEMSNAVMRMSALGA
AMILQSNGMETVMQVCCRDRNRLALQADLLAASACGIKNVMAVAGEDPSFGDHHQAKAVY
DIDLPDMLQALQTLQSGRDMAGIELSGKPSFLVGAGINAAAQGSALDLELEEMHSKIEAG
VRFFISPPVFDLHAIDSFLKKVDPRSIHLIPTVLLLKSLGMARYINIHMDHIHIPDPLIA
RIQKASDKVGECVAIARETVTALKENGFSGVLLSTLGWENRLPDILQTS
>A0A523R5B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLEKVLKAGHFAFTGELGPPRGTTAEEVREKCKHLKGLVDAVNITDNQTAVVRMA
SWAACLILIQEGLEPNFQMVCRDRNRLAMQADILGVYTHGVRNMLCLTGDHCMFGDHPDA
MGVFDIDSIQLINMVKTMRDEGKFQAGADIEDPPKIFIGAAANPFADPYEWRVYRLAKKI
NAGVDFIQTQCIYNMDRFKKWIQQANDMGLTEKVYILAGVTPMKNVGMARYMQKKVPGIE
VPEEFIDRLKGVDKKKVADEGIKIACEQVEEFKEMKGVHGVHMMAIEWEHKVPEIAERAK
VLPRPVMD
>A0A1G7ZIF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteribacillus persepolensis|TrEMBL
MNVLEKLQHSMLVGDGAIGTYLYEKGYRGSFEKLNIEEAETITAIHKEYVAAGADVIQTN
TYAANKIKLEKYGLHEQAGAINKAGVQLAKEAAADDAYVFGTIGGIKGVQQLDVTNDDIL
DAFKEQAEALLSENVDGFMLETFYDIHELLGTVTLIRELTDLPIIAQAALGDVGVMRGGL
PVSDVFQRLKNAGADVVGLNCRMGPYHILRSLETVPLMEDVFLSAYPNASLPDLDDGRFV
YQSNPDYFYERAQDLKQQGVRLIGGCCGTTPEHIAEIAKAVKGTAPVREKAIVTPVQSDA
FDNAPPAQSHVRLDEKNTEPTVIVELDPPKKLSTQKYIEGAAALYRAGADAVTMADNSLA
SPRIDNLAMGAMVKNQTNARPLLHVACRDRNLIGLQSHLLGIHALGIHDILAVTGDPTKV
GDFPGATSVYDVNSLNLISLMKEMNEGRSFSGKSLGEKTSFTIAAAFNPNVRNVDRAVKR
LEKKVDAGADYFMSQPVYGKEQFKEIYEATKHLDAPIYVGIMPLVSSRNAEFLHNEVPGI
KLTDETRKIMADCGQDREKAQKEGIAIAKSLIDEALLYFQGIYLITPFLRYDITTELTSY
IRAQALQR
>A0A417BPY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium AM43-11BH|TrEMBL
MKIIDKLNEDRIHISFEVFPPKTDAGFEKVKDATDKIAQLNPSYISVTYGAGGGTSKNTA
KIASHIKHELGVESLAHLTCASSTKEEVRQVIENLKQLEIENILALRGDIVPGMTFPSED
RFHYAYELVEEIKKHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITTAAQMKRSQELSGTVFPRRFLALLDRFGDYPD
AMKQAGIAYATDQIIDLLANGVKNIHVYSMNKPEVAAKIMENLSEVIKC
>A0A1I3TTY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus centrosporus|TrEMBL
MIELTTGKKDLREYLQDHLLVGDGAMATQLHRLGVPLGVSFEELSLSNPKLVQEVHDSYY
AAGARLLETNTYSANRDSLSRYGLEHRVARINRLAVKIARESARDDAYVAGSIGSILAGR
VRKKVLDEYRDQYEEQAIALLHAGVDGIILETFLDLEELLMALEVIRPLTDAPLIAQLAT
LEVGRTRDGYSLTDAFGQLKQAGADIVGLNCRLGPAEILRSFENTQVPHGALLSAFPNAG
RLGLTDGEYAYKSTPDYFGQSALRLREQGIRLIGGCCGTTPEHVKAMADALESLEPQERI
NPTIVPGDRPQVTVQSIRDQSKPSIVERVKTETTVIVEFDPPRDLDAESFLDGCCELHRA
GADAITLADNSLATVRMSNMALGALMKSRHGIDPLLHIACRDRNLIGQQSHLMGLHALGI
DQILVITGDPSRFGDLPGATSVFDVTSFDLIRMVKQLNEGVSFAGRPLKQKAQFIVGAAF
NPNVRQMDAAIARLEKKVEAGADYIMTQPVYDVESIKQVYEATKHIGIPVFIGIMPLTSL
RNAEFLHNEVPGIKLSPEALERMRAVEQGEAARQEGIKMAKELLDTAIQYFKGIYLITPF
HYSSMAAELVQYVRQQSALVKTATH
>A0A269WBF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. 7541|TrEMBL
MKPDLRQALEKEVLVGDGAMGTYLYQQGFPVGISYEELNLTSPEVIRNVHRQYIEAGARV
IETNTFSANYDKLSKYGLESKVAEINRAGAMIAREAAGEQVYVVGAIGSIRAGRRRDLSS
SELKRYFEQQLDVLLSEGVDGILLETFYDVEEIQLALKEMRRLSSLPVICQFAVEDVART
LDGYTMPEACRILSDEGADVIGFNCRTGPNGIKRALETLEGELNLPASVFPNAGIADYVD
GEYRYGASPSYFGSTAVPFADLGARIIGGCCGTTPAHISEIAKALSGYTPVPLPKRDEAI
PSRIVVQEPGSSDASRGDDLNQSPSLVDLVKERHTVIVELDPPRDLDITKFMKGAEALKK
AGADALTLADNSLAVTRMSNMALGHLVQERVGLRPLIHIACRDRNLIGTQSHMMGFDALG
IDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNEGIAFSGKPLKQKAKFVVGAA
FNPNVKHLDKAVQRLEKKIASGADYIMTQPVYDPELIVKLKEATAHLDIPIFIGIMPLAS
GRNAEYLHNEVPGIQLSDAVRERMAGLEGAEGRAMGVQIGQELLEVAMEHFNGIYLMTPF
MFYEMSVQLMEHVWEKSGRPTPHLFH
>A0A7K3XN24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariniphaga sp|TrEMBL
MKVIDIIQQSEKTVFSFELLPPLKGQKPDKLYRTIDELIEFNPQYINITTHRDEVEFREL
PGGLMQKRIVRKRPGTVAIAAAIQNAYNIPVVPHIVCGGFTKEETENILLDLNFLGVMNV
LALRGDGLKSESFFNPERDGHSHAQELVEQIVNLKQGKYLDPEIKNTAELDFCIGVAGYP
EKHYESPNIDIDLLNLKEKVDAGADYIVTQMFFDNQKYYDFVNRCRAIGITVPIIPGIKP
LAMMNQITVLPKLFSIDIPEAFAREVRKCKTNDEARAVGTEWAIEQSRDLIAHKVPCLHI
YTYGISDNTRQIAKAVI
>A0A6G2RNS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8354|TrEMBL
MALGTASTRTDRARTVRDLLASGKRSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTAELRNVIGQYADAGIRNMLALR
GDPPGDPMGEWIKHPDGVVHAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDTDIRHFVD
KCRAGADFAITQMFFYPEDYLRLRDRVHAAGCPTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAARILAVKDDPAAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQRP
>A0A1G8XBQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus typhae|TrEMBL
MKPDLRSAWKNNVLVGDGAMGTFLYQKGFPVGISYEELNLNSPEVIEDVHRSYIEAGAVL
LESNTYSANYDKLAKFGLEGRVEDINRAGVRIARKAAGEAGYVVGAVGSIRAGKRANLSA
SELKRFYTQQFAALLEEQPDGIMLETFYDVEELHLALKAVRKLSSLPVICQLAVDETART
LDGLTLPEAFHILEQDGADIIGFNCRTGPNGIKRALRTLQGSLALPVSVYPNAGIADYVD
GQYRYGATPDYFGQMAPVFADMGSRIIGGCCGTTPQHIAEISAALRGYVPQPLPEPAVKQ
SAGSIIVHEHLEEDGGRSGREPNLVDLVKERHTVIVELDPPRDLDITKFMKGAEALRRAG
ADALTLADNSLAVTRMSNMALGSLVQARTGLRPLVHVACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIKQLNDGIAFSGKPLKQKARFVIGAAFN
PNVKHLDKAVQRLEKKIASGADYIMTQPVYDPELIANIAAATRHLDIPIFLGIMPLASGR
NAEYLHNEVPGIQLSDEVRRRMQGLEGEAGRAEGVAIAKELLDAATAHFNGIYLMTPFMF
YDMSVQLLEYIWAKQGRKLSPLFR
>A0A6N4AS23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Synechococcus spongiarum LMB bulk10D|TrEMBL
MKSQVSPSAFQQALASGQPVMTAEISPPRGGSVQHVLATADRLRGRVHALNVTDGSRAVM
GMSSVAVCRLLLERNLEPVLQVGCRDRNRIALQADLLGAHALGLRNVLCLTGDPVKAGDQ
PKARSVFDYEAVRLLRDVKNLNQGLDALEQLLPDGPTALFPGCAADPQSPSWSGLKGRLQ
RKKEAGARFIQTQMVTDLAALRRFCRELATPLGLPVLAGVFLLKSGKNARFINRMVPGAS
IPDQAIARLDGARYPQAEGIRMAAEQVAAYLEVAQGVHMMAIKAESAIPQILDLAGVPPL
APPIVAGVDLKSLAAEPC
>A0A7M4DRE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Occultella aeris|TrEMBL
MTTATASFSCPKSMTYGPCAGVHEDGRCEVAEHPCVFLDGRPRAWAGVHRPMGEPVHPEP
IPLTPAGADFADVLARRQIVTSDFPIRAARRDAVVAGAAALREHVDAVLIGEPPSVRVQF
PPAYRTRLLRAEGVGVWSSLNCRDRNRVALEGELAALADAGVSAVHCITGDHNRSGRRPE
AMPVFDLDSTELTSIAKANGLLVSVAESPEAQPRVQRPARFAQKAAAGADLCFININSGP
HIVDGFLRAVEALGTRTRAVVCVPFVVDVGSAAIMTGLDSHLMPERFIEGVLDADDPREA
GIRAAVALAEQYLAVPGVAGVCMSGGAGRGLELDYARAMAEAARRLGLR
>A0A3P3VK16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aestuariirhabdus litorea|TrEMBL
MNTQNRFLKRYSFEFFPTKTDAGAANLLATAQQLASYQPDFFSVTYGAGGSTRDRTVSTV
LGAQQSTGVPTAPHLSCVGDSKQEILDLLDHYRANDIQRIVALRGDLPSGMGLASSEVRY
ANELVSLIREHSGDHFEIEVAAYPEVHPQAPNAERDLLNFKRKVEAGADAAITQYFFNAD
SYFHFVDRCESVGIDIPIMPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIVSI
QRFGEEVVTQMCERLLEGGAPGLHFYTLNQAAPSLKIWDNLKLSERR
>A0A2S6SLX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha5_Bin9|TrEMBL
MDTNQKEFNIKKLISNYSIETTPQVYLKYGGFHEFLTNHNDIYVTFLPNENSKNVIQTCK
KINEEGLNAIPHLPARNIENNEELNTFIASLSEIAGCKKILLIAGSGKKKGSIGSSIEVL
ETGFLSKYNFVQVGVAGHPDGSIDISKKELDDAIISKNKIAKDVDYKIYIVTQFFFEIAS
FIKWEKHINKIGNQLDIHAGIPGPATLKTLISYAKSCGISNSIRFLSKQAFNLSKLATTN
CPDKLITELSIYKDENSLTKLKKIHMYPFGGIKKTSNWINSINNSTLKFNSKNEFTII
>A0A100JNU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces scabiei|TrEMBL
MLATGRTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSVTYGAGGSTRAGTVKATEQ
IAADTTLTPVAHLTAVSHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVAHPQGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSPDWDSDVARFVDKCRAGADYAITQMFFQPE
SYLRLRDAVAKAGCETPVIPEVMPVTSVKMLERLPQLSNAAIPNALKERIVTAKDDPAAV
RSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGPHHPPRA
>A0A4Z1HJJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryotinia narcissicola|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHHIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAAL
EEVKNDDAAVRNIGKDLVAEMCRRILQAGVHHLHFYTMNLAQATRMVLDELRLTPSNQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLENSIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQQEP
DLTYYAVKKTGDVQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLNEPFETSQNGD
VDGVRFIEPQTVPLTNGEANGH
>A0A1X9YVN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter actiniarum|TrEMBL
MKVTDHFKNANGKTLFTFEILPPLKGENLHTLYSHIDPLMEFNPPFIDVTYHREEYIYKQ
RENGLLEKRSTRKRPGTVGICAALQSHYKVDTVPHLICGGFNKEETENALIDLHFLGIDN
VLVLRGDCVKSEARFVPEPGGHNYASELIEQVVGMNNGVYLDDEQANTNGTDFCIGVAGY
PEKHFEAPNMRMDLRWLKRKVELGADYIVTQMFFDNQKYFDFVKLCRQEGIEVPIIPGLK
PLTTKTQLSLLPSLFHIDLPCELAEAVEACADNKAAAEVGVEWAIKQSKELMEFGVPCLH
YYSMGKSGSVRKVAEALF
>A0A1N6WRJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. RU33A|TrEMBL
MAHIDENPLGPHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLSSPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMAKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDSVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGILKGRRPWKREHARADDIAAQRMREIGADPVQDQQTLAGLAA
NTQPH
>A0A371I4N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucuna pruriens|TrEMBL
MKIIEKILAADPNRVVFSFEFFPPKTEDGVDNLFERMERMVAHNPSFCDITWGAGGTTAD
LTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQDKF
VQVEGGFACARDLVKHIRAKYGEYFGITVAGYPEAHPDVIESNGLSTPESYQSDLVYLKS
KVDAGADLIVTQLFYDTDAFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTRI
PADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEETKISRSLPWRRPANVFRVKEDVRPIFWYVTFANFSVLFQNIRRFMRPRARDKKLTE
EWAVPLKSVEDIYERFRMYCLGKLRSNPWSELDGLQPETKIINEQLEKINMKGFLTINSQ
PAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKLDALVDKCKDRTSLTYMAVNKEGS
WKSNVGQTEVNAVTWGVFPAKEIIQPTIVDPVSFNVWKDEAFEIWSRGWASLYPEGDASR
KLVAEVGASYFLVSLVDNDYINGDLFAVFADI
>A0A157Z316|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia fortuita|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRASRAELKKLSPKFVSVTFGAGGSTQQGTLDTVLEMAA
EGFEAAPHLSCIGSSKENLRAILSQYREHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQEHGDWFNIEVAAYPEFHPQSRSPKADLENFARKVKAGANSAITQYFFNADSYFKFVE
ETRKLGVDVPIVPGIMPITNFTQLMRFSDMCGAEVPKWIARRLESFGDDRESIRAFGVDV
VTGLCRRLIDEGAPGLHFYTLNGAWASKTVCARLGFKSV
>A0A7V8GLM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas broegbernensis|TrEMBL
MTPISFEFYPPKSDEQRAQLDRAAKRLGAHAPEYVSCTFGAGGSTLSYTSETVRHLHQQH
GFDAAPHLSCVGGTREEIRELLRLYRAIGCRRIVALRGDLPSGMGHPGDLRYAAELVELI
RADHGDHFRIEVGAYPETHPQADSAVADLRHFKTKVDAGADAAITQYFYNADAYFRFVDD
TRALGVDVPIVPGIMPISNYAQLRRFSEACGAEIPRWMDKRLQGFGDDAKAVREFAADAV
AALCRRLVAGGAPALHFYTLNLARPTEAVLQRLG
>E9BV23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania donovani (strain BPK282A1)|TrEMBL
MSKLISDAIAAEDVSKWYTSYELYPPRSEKAEEDMMKVLVPNFMRQSPVFLDLTWGAGGR
TSDTTMRLCKDLQHAYPDTPINMHITCTNTPKGLINEALDFAKTHGIRNILALRGDPPRG
EEFRADPDGFACARDLVRYIHDTYGDYFCVSVAGYPEGHPSRIAEDGAISDEDHQKELEY
LKEKVDAGASFIITQLFYDASLYVQFVKRCREIGITVPILAGLLPITTYAGFVRMVSLCK
TSVPSDVKKRVEELKENPDGLKEYGVEQCVQMIECIRTSGLDYHHLHFYTLNNSAQTFKV
LKRLNALVE
>A0A7S6RVV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas sp. H1_AOB3|TrEMBL
MQSQKKFTPTFSFEFFPPQTPEGMEKLRATRIQLAQFNPKFFSVTFGAGGSTRERTLETV
LEIQAEGYPVAPHLSCIGSTRDNIRSILEKYHSHGISRIVALRGDLPSGMAQAGEFRYAN
ELVAFIRKEFGDTFWIEVAAYPEYHPQARSALEDFTNFRRKVEAGANAAITQFFYNVDAY
LHFVEMCEAADLNIPIVPGIMPISKFSQLARFSDSCGAEIPRWIRRKLESFGDDIPSIQA
FGLDVVTALCARLLEAGAPGLHFYTLNSAVLPTKIWQRLGL
>A0A7W2A873|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenactinomyces guangxiensis|TrEMBL
MKKRPLKEHLSDSLVTGDGAMATYLYQQGVSIGHCNEELVLSNPAFIANVHKAYYEAGAR
LIETNTYGANRERLTRYGLESKVTRINREAVKLARNTVGEDAYVVGSIGSICAGRVLAFD
EDEYRDMYEEQATALLHAGVDGILLETFLDLKEVLVAVDAIRPLTDLPLIAQLSTIEVGR
TRDAFSLSEAFQILARHGVDGVGLNCRLGPMEILRSLEKTVVPEHLILSAFPNAGRLGVS
DGEFKYKSSPGYFEETADLLVAQGVRLLGGCCGTTPDHIRRVAAALAGKKPVQRVNPELR
QIEVTGAEHAETARKKPTVVDKVKYGRTIICEFDTPKGLDISGFLAGAERLHQAGVDTIT
MADNSLATARMSNLAAGAILKSQLGIEPLVHVACRDRNLLGQQSHLMGLHALGIDQILVI
TGDPTRVGDLPGASSIYDVTSFELIRMVKQLNEGISFSGKQLKQKASFVVGTAFNPHVRQ
LDAAVRRLEKKVAAGADFIMTQPVYDEKGILDVYEATKDVGIPTFIGIMPLTGYRNALFL
HNEVPGIKIPQSVLQRMEAQTDKESARREGVEITKNLLDVAMEKFRGIYLITPFSFWQMT
VELTSYIRRKDHKRAAAQVS
>A0A7R7CJ31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L-8-10|TrEMBL
MIEKRPPQRDENPEGIHLPLEPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RARIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVGNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNGKFLSGRKLTTPPQ
LFLGAAINPFAPPYDFRPYRLGKKIAAGAQFVQSQYCFDVPMFREYMKRVRDLGYAEKCF
ILVGVGPLASARTARWIRSNVPGIHIPDAVVERLEGAQDQKKEGKKLAIDIINEVKEIQG
VSGIHVMAYRQEEYVAEIVDESGVLKGRRPWKREPRSDDHVVAQRLDHILHDNVTESQID
MVKTAH
>A0A7R7CQY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L-8-10|TrEMBL
MDTTSRLHKARPQFIGASTELAPSQAIDSPDLPGLFPQGVRVYITDIGTDDTPTLVRAAR
RVTDLGYTAVSHIACRRQTTRIALEERVRALAEEAGVRDVLIIGGDVKTPAGVFSSSMDV
LETGFLDKYGINEIGIAGHPEGSRDFSDEVANGALLIKKAWGERTGARLRIVTQFGFDAE
KFIAWADGLAGLGIDLPVHLGVAGPAKITTLLKYAAVCGVGNSLTFFKKRSASLAALATS
HSPESFVSPVEEHFRANPGSAIEQLHVFPFGGIKNASRWLHERGSWASEERPAARLEFRT
H
>A0A370FPH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudacidovorax intermedius|TrEMBL
MALPISFEFFPPKTPEGAVKLRAVRAQLRARAPQFCSVTYGAGGSTQAGTFATVKEILEE
GTDAASHFSCIGATRETVRDQLHQLKAMGVRRLVALRGDLPSGYGIGGEFQYASDLVAFI
RAETGRDFHLEVACYPEVHPQARSPQADMQAFATKVRAGADSAITQYFFTPEAYFRFVDE
ARAAGADVPIVPGIMPITSSTQLMRFSDACGAEIPRWVRLRLQSFGDDTASIKAFGLDVV
AALCERLVAGGAPALHFYTMNQAAPALALLDRLGLGE
>A0A0N0GI01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. cilantro|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLQLPR
>A0A4Q9KJU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propioniciclava tarda|TrEMBL
MTSQTIAQRLGEPDRPTFSFEFFPPSDAAGAFVLLDTVVNLRELRPDWVSVTYGATGATR
ERTFDAVRAIQRHGGVQTMGHLTVSGQTRDEVAAALASYAELGVKHILAIRGDMPAGPLT
PFEAHPDGLGNATELVRLVKASGDFEVGVAAFADGHPAQFDLDLDARILLDKQEAGASFA
VTQMVFRADSYLALVERFRALGGTIPIVAGIMPVTNLGQIARFKAMAGDVMPDDLVAELM
TAADDKARFREIGLERITRLCDQLLAGGAPGLQFFTLNRSTATNEIVARLRQIPPHRA
>A0A2D7B9X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedosphaera sp|TrEMBL
MEFIKDIHREKIATGKPAISFEFFPPKTEKGEAQLFHAVLPELLKIQPDYCSVTYGAGGS
TRGKTLEMVSRIQKDFQLTCMSHLTCVNATREEVNQVLIEANKSGIKNILALRGDPPGGK
GDFQATEGGFTYSKDLVAFIRSEFDFSIGVAGFPEGHIDCKEGREVDWDRLKEKVDSGAD
FIITQLFFDNDDFFRFRDHLVKKTGMTKPIIPGILSVLSTRQIKRFTELCGASIPESMLN
RLDDLAEDDAAATEFGIEHAVRQCEALLDAGVPGLHFYCLNKSYSTNRIVDALSRYR
>A0A1F9P1P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYB2_FULL_66_7|TrEMBL
MNTEATGLQKRIASGKTILLAEIHPPQSGDPAPLRAAARRYVGKVHAVGVSDNRDRVAMS
ALAAASLLKDEGLEPILHMTTRDRNRIALVSEALGAQALGIRNLLCTSGNHQTLGTFRAA
RNVYDIDAVQLLQACAHLESDGGLLGEKGLEGAGPFCLGAVASPDADPPALQLLRLAKKT
RAGAKFLVTQPVYDLERFEAWWKEVTLRGLHEQAAILAGIHPLSDTHFGQAGSGPQQGIP
DSQAARLASMKDPGAWRDAAIEIALETIRRLSNLHGIRGFCISADGDHEATVQIIDESGL
AND
>D9RTW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella melaninogenica (strain ATCC 25845 / DSM 7089 / JCM 6325 / VPI 2381 / B282)|TrEMBL
MGNNITDIKQLLNDETDEKHFSFEVLPPLKGNGTASLFRNIDQLKEFNPSFINITTHHSE
FVYHEREDGLLERQSIRRRPGTVAIAAAIQQRYGIPVIPHVICSGATKEDIEYELLDLQF
LGIENLMLLRGDKAREDRFFTPTEGGHSHTTELIEQVNSFNEGIFTDGSTMKHPGKPFVY
GVACYPEKHEEAPNLEQDLRYLKMKQDLGATFAVTQLFYDNEKFYNFVDQARKMGVTIPI
IPGIKPFAKLSQLNVVPKTFHCDIPEELAGLALLCKSDEEARLLGIEWAVRQVKDLYAHG
FNNVHFYTVSAVSSVHEVMKRLVETGLLKQNSK
>A0A317RRW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium limosum|TrEMBL
MTIPEIMKNRMCFSFEVFPPKEGQPLEPLLDTLDHLYAFKPDFISCTYGAGGTNAGRNVE
ICKAIKDSGATIPITHFTCIGNSKDKIRDELRNYLSLGVDHILALRGDFPKGSASTGGDF
DYANELISFIKEAFPEFSIAMAGDPEKHFEASSFDEDIAHLRIKQDAGADFIMTQLCHDV
AHYEWWVEKIRKAHITLPIDVGIMPVLAKDPTIRMAVSNGSSIPRDLAEIIARYGDNPED
FKKAGMEYTVKQIHRFISAGIDGLHIYSLNKWADISEIVRAAGIR
>A0A363T6B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MPGFTPVRRWQPPYYPFRRDPYGLRVLESIERLIKGPMFGCRMCGNCLLQETAFICPMEC
PKGERNGPCGGSTTEYCYVDKTRPCVWYKIYERAFKMGREEMLMEVLPPLDWDKTGGETW
GDVYHQIKKVGGRKFFGGILKKQTRPEVWSAVFQPIRQPDWWKGDAEYHAPAYAEPVSNL
EKRLKAGEFVVTTEVAPPATVATNKLIKNIELVKPYVAAINFTDCPSASPRMSSWACSSF
TVQAGAEPVMQIAARDRTRIGLQAEVLGSNALGVRNVLCLSGDSMNMSSTPKGKMDILDM
DSIHMLWILRRMRDEAIYMDGRSIMFPPKYFLGAAGSPYASNPKIQAIREHKKINAGAQF
FQTNLVYDPQKLDDWLEALEVRGILDKVYILIGITPLKSLKVAKYMNEEVPGVTIPDHLV
KRMEAAGDKADEEGVQIALELIDAVKNKKGVNGIHLMAVGWEEIVPRIITEAGILPPDFT
PPPAPAPKG
>A0A1Y4QPH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelatoclostridium sp. An15|TrEMBL
MKIIDMLLKKPTLSFEIFPPKNHDGDISSIYKTIDELSALKPDFISVTYGAGGSTTEHTV
EIASKIKNQYGIEAVAHLSCIDATSKQLTKILNELKDNNIQNILALRGDYPKDYDPKTAP
HEFKYASELNTFINKNYPDTFCLSGACYPEVHQEAVSLEADLEALKKKVDSGAQYLITQL
FYDNNYYYRLVREARLKGINVPIIAGIMPATNARSLLNIAKLSGGNIPYNLSASLERFRN
NPKAMKEVGLNYATNQIIDLITNGVDGIHLYTMNRPEIAKEILMRTNNIFAEFKND
>A0A1Q7DP00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium 13_1_40CM_69_22|TrEMBL
MSEVTLRKLLDDGRVHVLDGAMGTMLYAKGFFLNVCYDELSLKQPKLVQEVHEAYVRAGA
EILETNTFGANPVKLRSYGLADDTEKINQAATELARAAAAGHASVVGAIGPLGVRIEPFG
ALSREEACAHFGRQVDGLLAGGVDGFILETFSDTDEIHAALRAVRSRSDLPVIAQMTIGD
DGLTHYGTGPETFAKQLTEWGADVIGVNCSVGPAGVLEAVEKMVKVTDRPISGVPNAGLP
RDVGDRKIYLASPEYMASYARRMIEAGARLVGGCCGTTPEHIKKIRDYVASVVPRHPPVV
VSRAEIRAPAGAEAVPLAQRSRWGAKIARGELVTSVEIVPPKGVDATPMLEQCRALKAAG
VDAVNVPDGPRAQSRMGVLPSAILIEREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLR
NILIITGDPPKMGPYPEATAVFDIDSIGLTNLVFRLNHGLDPGNNPIGAPTRWAIGVGVN
PGAVDLDRELSRFAWKVDAGAEFAVTQPVFDPAQLEAFLARVGQFKIPIVAGIWPLISLR
NAEFLANEVPGVSVPESVLARMRQAQEKGKEAALAEGVQIAREMFQQVKRSVQGVQVSAP
FGRVEVALEVFG
>A0A0B5NSW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKAMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8J8B5K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinanaerobacter chloroacetimidivorans|TrEMBL
MKIKDIFETKKTVISLEVFPPKIDSPVETIFKTLDQLKDINPDFISVTYGAGGKAKDRTV
EIASKIKNEYHIESLAHLTCISATKKQIKESFEEMRVNNIENILAMRGDIPEDPDFDFPN
PLQYEHASDLIKEVKAEGDFSIGAACYPEGHVDCESKVKDVKYLKQKVEMGAEFLITQLF
FDNELFYRFMDEIDLAGINLPVSAGILPVLNKNQIIRITKLAGCAIPPKFQRILNRYEDN
PEALKEAGEAYAIEQIIDLMAWGVRGIHLYTMNKPDTAKRIIGNIENIRKLQG
>A0A842ME22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanosuratincola sp|TrEMBL
MNRVFSKLMSEIQSGKFVYTGEISPGKTTRIEGLIRSAGVLGKHVTACNVTDNPRARANM
SSLAASIAIQEKAGVEVICQMTARDRNRIALTSDLLGAAALGVRNVLVMSGDHPSLGDNP
LAMPVYDLDSAHMVELVRRMVDEGTDLVGNRIDGEVRLHVGVVGNPNADPIEVEIAKLER
KAEIGAEFIQTQAVFDIEVAERFLDSVEGIGVPVLIGIMPCRSFRTAEQIEKNVPGIRIP
QEYLERLRGAEELPDLASKEERADFINEEYFSSMISDLRRTGRLAGAHIMGVSYNQIVGR
IVEAVQKREGGKRSKRKG
>A0A1B1LBL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGSATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A833M6Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiaceae bacterium|TrEMBL
MNQFRLSRRPDIGEKIRVSFEFFPPKSDEMEERLWDTVKRLAPLNPRFVSVTYGAGGSTR
ERTMRTVRRILTETDLLPAAHLTCVGADRDAIDAVIAEFAEMGVNRFVALRGDPPEGVGS
VYRPHPGGYANGAELVAGLKRHGDFDISVSAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNIGQVVNFSSRCGAHVPEWLRERFE
GLERDPQTHALVAAAVAAEQVLDLVERGVGDFHFYTMNRADLAFAICHMIGIRREQGGAD
SAAA
>A0A532UPF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium B3_Pla|TrEMBL
MRSTGTLEKVLTAGKFAVTAELGPPQNSNPEAIKKKAKHCLGNVDAANITDNQTAIVRMS
SIAAGSIALSCGVEPVVQMVCRDRNRLAMQSDILGAAALGLPNLLCLSGDHQTFGNHPEA
KNVYDIDSMQLIAMVKKMRDGKQFLCGDEIKEHEPKLFIGAVANPFADPFEFRVMRLAKK
IEAGADFIQTQCIFDINKFAGWMKMVVKEGLHKEVYILAGLTPVRSHRALTYMKNNVAGM
SIPDELITRMESADDPKEEGVKICLEMIKRIKDIEGVSGIHLMPIGWESITPVIMERAGL
LPRPKV
>A0A0V1F9I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella pseudospiralis|TrEMBL
TVIPTCSDVTDSSPRTHLHIFVNRVYNAPSLKPVRCFVIDVGVCFEYSDVSLMASLEAVE
LKTTRHDLNSSPKKSTDKICQPLIDRIKQNMSSGRRFFSLEFFPPHTPEGLINLLNRVDI
FANSQPLFVDVTWVMRSDPASEKVTSSSSLADCVLNFCLLDTMLHITSVQYNEKTVLSNL
ERVKKIGIRNILALRGDISDDANVTATDFQYACQLVRFIRSHYGDYFTICVADAGADFII
TQLFFDEMHYFKFVNDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSKIVIPDSVLTTLES
IKENAEAVRNFGISFAVELCRKSILEQIGLWKESPVRMLPWKKHPVHSVRCREAVRPIYW
NTRPKSYLCRTRDWKQFPDGRWGDLGNPAFGDLKHYLFSCIDQMNDSCALDMWDKELSSF
EHVRDIFCNFIARTPNRHGHTVRRLPWNENHSDPAVDVLKDELIYYNSNGILTINCQVAV
NGLPSNDPIFGWGEANGYIYQKGYLEFFASSKCTTILLNHVQNFPSINYHAINFDGSFET
LNYDEDATMALTWGVFVGQEILQPIVANAASFRVWKDEAFDLWQRWARLYESGSIGRKLL
QSIHDDHRLITLIDNDYPQPCSLSALLRAVIDECCEEKKIDDE
>A0A2C8ZF30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. OK233|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLASLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFAHKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTDLCGRLIDAKVPGLHFYTLNGAAATKAICERLGA
>A0A0N0DI21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium langsethiae|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WEAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPSAERP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKTIQDIAQLFVSYLNNKIESLPWSESPLTTEADEIREDLIE
LNKRGLLTINSQPAVDGVKSSHPIHGWGPDNGYVYQKSYLELLVHPSVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPV
ANGAVDTEPIANGTAAAAVAN
>A0A523TQT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MKVIDLWKSDQKTTISFELFPARSDKAAESLEKTIEQLTALNPDFVSVTFGAGGSTREGS
RQLLQKLKHEKGLDVLAYFACFGLGPEDIVSVLDSYRAIGIESILAVRGDAPRDEAFEPH
PDSLQYASDLVAFIRQRYDFCLGVAAYPEGHIDAPDIKKDLEYLKLKVDQGAEYIITNYF
YDTRFFFDFVDRCRGIGIEIPIVPGIMPIYSVKMMEMLAGMCGATITDEVRKGLDSFEEG
DKDALIAFGIELAYRQCAELLRAGVPGLHIYTMDRSMSTVGLVNRLRADGLL
>A0A4R5PJK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudohoeflea suaedae|TrEMBL
MSDTNPLGAHLPLDPKPGHSSLGRLERVLRRGEFAVTAELNPPDSADADEVYDRAAVFDG
WVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMGVC
NIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESRFLSGRKLTKPPQVFLGAAI
NPFVPPQEFRPMRLAKKIAAGAQFVQSQYCFDVDMFRSYMQRVRDLGLDEKCYILCGVGP
LASARTAKWMRSNVPGVHIPDHIIKRLEGAEDQKAEGKRLCIDIINEVKEIAGVSGIHVM
AYRQEEFVAEIVHDSGVLKGRKPWRKEPNLANEAAEARLEEADDAARVSPHTLAGVAAEG
EA
>A0A1C7GLL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungateiclostridiaceae bacterium KB18|TrEMBL
MKIKELFNRGNVNFSCEIFPPKKDADFTEVFDVVDRISRLGADYISVTYGAGGSTSKKTV
EVASYIQNKCQTTALAHLTCIDSTPEQIQTQLAEFKANGICNIMALRGDKPKDFTGHAYY
NYAIELIKDIHAYGDFCIGAACYPEGHIECAHKQEDIFHLKEKVDAGVDFLTTQMFFDNN
LFYKFLYQALAAGITVPIVPGIMPIINARQVKRSAELSGANMPARFLAIADKFASDPLSM
EQAGIAYATDQIIDLIANGVKHIHLYTMNRPNTAEKILGNLSHIIR
>A0A7C3IRG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTRSFKEALHSGAFVITSEIGPPKGTNLDPMIHHIQLLKDKVDALNVTDHQSSVMRFPSI
GGALIIKELGGEPILQMTCRDRNRIALQAELLFAYTRGIYNVLCLTGDAVPVGDHKSAKG
VFDLDSSQLLRTVRLLETGKDLGDNALNGSVSFCAGAIVTPEADPIEPQLIKFEKKVESG
AEFFQTQAIYDLDNFCRFMEFARKFNVKILAGILLLISARMARYVNENVPGITVPLALID
ELAQAPKGGALTTGIEIAGRMIRRIKEERLCDGVHIMAIGKEEVVPEILKAAGINKFY
>A0A853RS29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio splendidus FF-500|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDVSVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A849MH85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MESQKQYTPTFSFEFYPPKTPEAIGKLQTTQAELAKLNPDFFSVTFGAGGSTRDMTFETV
VDIHNKTGIIAAPHISCIGSESNDIKAILDKYIESGITRIVALRGDLPSGSVGYGHFRYA
NELIEFIRKETGDHFHIEVAAYPEFHPQAPNPRADIENFKKKIDAGANGAITQYFYNPFA
YYRFIDSCEKIGLDIPIVAGIMPIVSCTQLQRFSEACGAEIPRWILKRLQEFGDDRVSIR
EFGVDVTTELCEQLLTNGAPGLHFYTMNQSVASTAIWKNLGIDQRVND
>M0M111|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halococcus hamelinensis 100A6|TrEMBL
MPFDSFDEQLTHLPDGAEVAITTSPSLGVDATVEAAESAAARGYEPVPHIAARYVKDREQ
FEGIVGRLADAGVTDIFVPGGDLEEPAGEFESAHDLLVVLDDLDYEFEEVGITGYPEGHD
FIPAETLAESMAEKEPYATYIVTQLCYDSDAVVEWVETIRGRGVDLPVEVGIPGVMKYQR
LLEISQKVGVGDSVHFLRKTTGIVGFVRQLIGSRGKYAPDDLIDGLARYAEDPDYDIRGV
HVYTFNQTPDTESWRRGRLAE
>A0A7X3QM44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTTVVEHRFQCPDTVQIVADFSPPKGTDPAPLDEASRLDADFISVNYSPGKSARVNSAIA
AAWIKQNAGKEVIFSLSTRDMNRVAAQGLLLGANMMNLENVVVLKGDSFTKTELAITKPV
DDYAPTGLIRAIADMNRGIDYKGLKLQSPTSFCIGATIDLVRSMDRQMELTRKKVEAGAQ
FFFLQALFSPERLAEFLKRYADRYGEELSALICCGVQVLVEDGVTFGVLPDWVSSALRTG
RSGEDIAVETTSRYLDAGQRSIYLLAPIFRGGRRDYVACQRVIERVRKL
>A0A7S8AWN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces violascens|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRAAADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A6M4CAU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vitreoscilla sp. (strain C1)|TrEMBL
MNRTPLSFEFFPARTEEGRAKVAVTRQQLRQFNPEFFSCTFGAGGTTRDGTLQTVLDIMS
EGTAAAPHLACIGSEESEVRHILNTYREHGIKHIVALRGDIPSGMGVMASDGFRYANELV
SFIRQEHGDWFHIEVGAYPEFHPQAKNAQSDIDYFVQKCQAGANSAITQYFYNIDSYFAF
VDAVQAQGVNIPIVPGIMPIANFSSLSRFSDTCGAEIPRWLRLKLQAYGDDTASIKAMGL
DVVTDLCDRLLSQGAPSLHFYTLNQAGLVSTVCQRLGY
>A0A5C6W0F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metabacillus litoralis|TrEMBL
MANKFLEDLKNKILIGDGAMGTMLYSHGVDRCFEELNISKPDDVQRVHEAYISAGANLIQ
TNTYGANDIKLSRYGLEDDIRQINKQAVAIAKKAAANSAYVFGTIGGVRSFKKSAHSNDE
IKRNFREQLFILLNEDVDGILLETYYDLEEMKAVLQIARKETTKPIIANVSLHEAGVLQD
GTSLRDGFLTLEDLGANVVGLNCRLGPYHMIQSLEEVPIPTESYLSVFPNSSLPAMNEGR
LVYESDESYFRESALKFREQGVRLIGGCCGTTPNHIKAMSEAVADLAPITDKQVRVPNNV
ITVSSDHSDDLPPLQDIVKQKRSVIVELDPPKKLGMTKFLDGAQALHDAGIDALTLADNS
LASPRVSNLAAGILAKEKTGSRALIHITCRDRNLIGLQSHLMGLHSLGMSDVLAITGDPS
KIGDFPGATSVYDVSSFDLISLIKQFNEGVSYSGKPLGDKTNFSVAAAFNPNVRHLDKAV
VRLEKKIAHGADYFISQPLYSNQQIIDVYEETRNLKAPIYIGIMPLTSSRNAEFIHNEIP
GIKLSDSIRETMAAAGTDKEQARLEGLAIAKDLIDTAFDLFNGIYLITPFLQYDLTVELT
NYIHEKEKQRAERKITHV
>A0A7V2LPR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTNLEKVLESGMFAVTAEAGPPKGTSAAVMQRKGEALRHCCDAANVTDNQTAIVRMS
SLAGCVLLKQQGVDPVMQIVCRDRNRIAIQSDVLGAIALGIGNILCLSGDHQKFGNHPTA
KNVFDIDSIQLIQALKNMRDEKKFLCDEEVSGEVPMFIGAAANPYADPFEFRLTRLAKKV
KAGADFIQTQAVYDIAKFAKWMKMVTDRGLDKETHILAGVIPIKSAGMARYMRDYVSGVS
VPDEIVSRMEQAKETKEEGVRLAVEIIEQLKEIPGIHGVHIMAVGWEDIVPEIVEQAGLL
PRPVL
>A0A7C3BJ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTKLEKVLESGHFAVTAEAGPPKGTNAEVIKKKGELLRNYCDAVNVTDNQTAIVRLS
SLAGCLLLKEQGVEPVMQMVVRDRNRLAIQSDVLGAVTLGISNILCLSGDHQKFGNHPTA
KGVFDIDSIQLIQTLKRMRDEKKFICGEDISGEVPIFIGAAANPFADPFEYRASRLAKKV
KAGADFIQTQAVYDVARFARWMEMVRERGLDRQVHILAGVIPIKSAGMARYMRDYVPGVI
VPDEVVTRMEKAASAKEEGLKIVLEIIAQLKEIPGVHGIHIMAVGWEDIVPELVERAGLM
PRPTI
>A0A7L0J1A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piprites chloris|TrEMBL
MVNETQQSCSASSGSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGHRVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIITALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6I1ZZY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTRLERILASGKFAVTAEAGPPKGTSAEVIRKKGELLRRCCDAVNVTDNQTAIVRMS
SLAGCLLLRQQGIEPVMQMVVRDRNRLALQGDVLGAVALGINNILCLSGDHQKFGNHPTA
KGVFDIDSIQLILTLKMLRDEKKFISGEDVSGEVPVFIGAVANPFADPFEYRVSRLAKKV
KAGADFIQTQAVYDVPKFARWMEMLTERGLDKKVHILAGVIPVRSAGMARYMRDYVPGVT
VPDEIVTRMEKADNPKEEGVRIVLEMY
>A0A6M8VW39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTNEDGKLQQNKWKTGQVVSGYGTIPARTAEDIIGDSGLSLPFIPPVESNLSVSFEFFPP
KTEKMEAQLWDSVAQLAPLSPEFVSVTYGAGGTTRERTHDAVIRIQKETGIPAAAHLTCV
GSSREEIDEIARRYWDEGIRHIVALRGDPPEGSKTYVPHPGGYDYASDLVAGLKKIGDFD
ISVAGYPEVHPEALSAEADFENIKRKVDAGANRIITQFFMEPEFFLRYRDKLAAAGVTVP
VVPGILPVNNFESVRKFSKMCNTHLPDWLALLFEGLDNQPKTRNLVAATVAAEQCRVLYR
NGVQNFHFYTLNRAELALAICHMLGLRETAAKTAG
>A0A7J5TUY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rudanella paleaurantiibacter|TrEMBL
MTKITDHIRNANGKPIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PMPDGSIKKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFTREETEDFLIDLHYLGID
NVLVLRGDPAKPFNTFKPKDNGYSYASELVEQVVNMNGGIYLHEEDTALAPSNFCVGVAA
YPEKHFEAMDPDTDFDFLKKKVEKGADYIVTQMFFDNQKYFDFVARCRAHGITIPIIPGL
KPLSTRRQLQILPKLFHLEMPQELVKAVEACENDAQAREVGIEWGIAQSRELMAAGVPVL
HYYTMGKADNVARIAREVF
>A0A7C2WSR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTIAELAKQGKFVITAEVGPPKGVDIQEMLENAELMRGKVDAINVTDQQSSVMRLGSLPV
CRLLIERDLEPVFQVTCRDRNRIALQSDLLGAYTLGIKNVLCLTGDFIALGDHPQAKAVF
DLDSVSLLRAARELEQGKDLSGNELAGAPNFCLGAVVTPGADPLEPQLIKLEKKVKAGAQ
FIQTQAVYEPEKFEAFMKSIAHLNVPILVGIVLLRSAGMARFMNKNVAGVHVPDSLIQEM
EQAEKRMQKSVEIAARLIKDMKSMCQGVHIMAIGMEQRVPEIIEAAEL
>A0A4Q3XMD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yimella sp. RIT 621|TrEMBL
MPDASARPHPSIPDLLHAPDTAFSFEFFPPKDDASEAILWDSIRRVERIRPSFVSVTYGA
GGSTRDRTVRVTSRIEHETTLTTMAHLTCVGSSTTELRQIVGQYAGAGIRNILALRGDPA
GGLGTPWTPHPEGLDHADQLVGLIRELGEFTVGVAAFPDKHPESGSLEDDAQVLIRKAQA
GASFAITQMVTDVDAYLRLRDLVAASGRSIPIVPGLMPVTAYGQLQRMTELNGQPLAAEV
VERIEAVKNDKSAVREVGIQICTEHAQRLLAEGAPGLHFITMNRSTATLEVHRNLVG
>A0A2H1KXL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. 239c|TrEMBL
MSITYSPATSTPRVSASAPLTLAEPAPAPSHRLRRALSFEVIPPRSATQAARMPELLRFL
DSLNPDYLAVTSSARSNWLQGTADFIEHIRAHTSLRPLAHLACTAGTQTELLGWIDHLLG
VGVRGFLAIRGDFPDGVSAVPTDHLPHADALVQLLRQIEGDNVACLAAGRLGIGVAAYPS
GHCESSGPDEDLNVLAAKQRNGADFAITQLFFDPYAYADLCRRADHAGITIPIIPGILPI
TDAKRLHTMGRLAGLPVPESLLARFDRAHDEATARRIGLEITAEHTSALLEQGAHGLHFY
TFNDLHTTEDLLSALQRAGVSLTSFQPSPPPRRWPPSPNHTPTKEKDTQI
>A0A086THE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acremonium chrysogenum (strain ATCC 11550 / CBS 779.69 / DSM 880 / IAM 14645 / JCM 23072 / IMI 49137)|TrEMBL
MLIKDMLAEAEASGQPSFSFEYFPPKTAQGVQNLYDRMERMYSFGPKFIDITWGAGGQSA
DLTLEMVLQAQNLYGLETCMHLTCTDMGREKVNEALDKAYKAGCTNILALRGDPPRDQEK
WTATEDGYQYARDLVRHIRKAYGDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDEGASF
IVTQMFYDADNFVRWVRKVRERGITVPILPGIMPIATYASFLRRANHMQCKIPQEWLDRL
EPVKNDDLAVREMGKTLVADLCRKLLANGIFHLHFYTMNLAQATRMVLEELNWAPSAERP
FKQALPWKPSKGPGRRTEDVRPIFWRNRTKAYVARTQDWDEFPNGRWGDSRSPAFGQLDA
YGVGLTGSNEAIRKKWGEPSSVGDVANLFCRYLNKEIDSLPWSESPLTSETDTIKDELYS
LNKRGFFTINSQPAVDGVKSSDPVFGWGPSNGYVYQKSYLEILVHPALFPKLLERIGQHS
ELTYYAVTKAGELQSNTPNEGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFQLGMDW
AHCFDASSPSRQVIETIMKVWSLVNIVNNDFHDRTTIFEIFKGLELDQDILDKQVTGGSP
LNGNHVSEPVANGNGATNGTNGAAQAAAATS
>A0A445L5K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycine soja|TrEMBL
MKIIEKIRAASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVQHIRAKYGDYFGITIAGYPEAHPDVIESDGLATPEGYRNDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKVSRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALSDYQFMRPRARDKKLVEEWAVPLKSVEDIYERFRLYCLGKLRSNPWSELDGLQP
ETKIINEQLEKINTKGFLTINSQPAVNGEKSDSPTVGGCKRS
>A0A2E8V8V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTSQESISNLQRIISNQQFAVTMELTLPDSPDPTQVINTALEIAPYADALNLTDSTSAVP
HFSSLAAATLLIQNKIEPVMQISCRDRNRIAIQGDILGSQAIGVRNILCVTGDGVQSGDH
PEAKPVFDFDSTSLISTINHMKNTNTFLSGREFSPSLKLFTGGAVNPFAPPFDFRPLRVL
KKYQAGASFFQSQFCFDIERLKTFMGQVEDLSNGNVPPILVGVGPIRSARVAKWMSANVP
GVYIPSKVIDRIDSYPRKEQSKVGKEICIEIVNELKEMRNIAGIHIMAYRWESAAIEIVQ
QSSLDKQARQVD
>A0A2H0CRT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium CG22_combo_CG10-13_8_21_14_all_47_10|TrEMBL
MKIIEKLSSASPVFSFEFFPPKDSEGFTALFETIGQLKPSAPGFVSVTYGAGGSTRAQTV
DLVGKIKNDIGIESMAHLTCVGHDQQEIRSVLESLQAQNIENVLALRGDPPQGEDKFIKP
EGGFEFGNELVGFIKNNFSFCIGAACYPEGHIECKDLNKDIENLARKVDSGVDFLVTQLF
FDNRYYFDFLDRAQKKNINVPVIPGIMPILNLKQIQRFTKMCGASFSPSLLNKFEGVQED
NEKVRQVGIEHAIGQCRELLENKAPGIHFYTLNRSKATLAILEALRDIT
>A0A2E5QBI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MDDFTAETTPFSAGKIGHFGEVLRSGTTVFVAFLPGTDYADFIAVSKRLRDEGMRPVPHI
VARSVPDKAVLDENLRQLVSEAGIDEVLIIGGAVDQPVGTFSDSMQIMETGLLDKHGINR
IGVAGHPEGSPDITDDGIRQALAWKNGFAERTGAELYVVTQFCFEAEPIIAWDKAIQAEG
NRLPIRIGVPGLATIKTLLNYAKACGVGQSMNFLKRQARNVPKLVMASAPDKQIVELARY
QARDPKCGITGVHMYPLGGLKKTAKWAYAVLDEKYDMNREANGFKVNVDL
>A0A2A5FDH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIKDILTKTRPISFEFFPPRXAEGIPAVLETMDELKAYCPDFVSVTYGAGGSTRAFTEE
ITLQIKNETGVEVMAHLTCVGQNKEEIDEVLQRLESEGVDNLIALRGDPPKGTTEFVPVE
GGFQHATDLLKYVKSNFKFGVAAACYPEGHTESVDLDTDLKYVKMKVDEGADFLVTQLFY
DNRYYFDFVERARAGGIXVPIIPGILPVLNSAQVRRFTALSGSEIPPDLDKLLDKYAESD
NSARDMGVEYATAQVRELWDSGVPGVHFYVLNRSYSVSRILDNLTISGHQRQD
>A0A2S6S6G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha5_Bin12|TrEMBL
MDNKEIINLKKLINNYTIETTPKNFEKISDLNNLLPKNTSIYITYLPNENYKKIIDTAKK
IKDEGFEPIPHLPARTIKNFSEVEKYLGMLSEISGAKKILIIGGSSYQNGNISSSMEILE
TGLIDKFNFTEVGLAGHPEGSPDISDEELDRAIIEKNKFVSNTQAKLYFVTQFFFETSSF
ITWEKHLEELGNKIDIHAGLPGPANILTLINFAKSCGIRNSINFLSKQALKISKLASTKA
PGKLVYELSKYKNSNSNSKLTKLHFYPFGGMKKTSRWIKALVDNEIRIDQNNDIEITNFD
L
>A0A451D0P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MITIFKDRKKKYNDEPVNLKNKIKISFEVFPPKNIFLENKLFHSVKMLNKCNPEFFSVTN
SINIDKYDKTFFVLKKMFPLTDAKLFAHFITIGLNESLIKDIAHKYWSHGIKNIIALRGD
LPFNYSKKVIYAVDLIKLLKSVNDFKILVAAYPELHPESRSLKEDLINLKNKVDLGATAA
ITQFFFSINKFLKFRDNCLMMDLKIDLIPGILPILNINQLKKFVNMTNIYVPRWILDFFY
KYSDDKDKCTDLSVSIAVDLIVSLYREGIKSFHLYTLNQSDLSLRIFYKLGLI
>A0A510UVP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas persica|TrEMBL
MSAATVHPPVAQPRPAGAPADGASGEPRTSASSGTHVAPEPRPLGTLDRPTLSFEFFPPR
NPQAAPRLWETVRQLESLHPDFVSVTYGASGKTRETSRAFVSRLLRETSLSPIAHLTCVG
TSRDEITTIVEEFLDEGVRSFLALRGDPPAGQTDWQAHPEGLETASELVGLLRDIESRRC
GASPAQAVRARVRPLSVAVAAFPRGNAATGGTRAQDVASLLAKQEAGADFAITQVFYDAE
AYLGLVAEARDAGVVIPIIPGIIPLTDPARLLRTQELTGVPVPRDLLDALGAADDPLTQH
RIGTRAGVDLVKGILDGGAPGVHVYTYNKHEAALDLLEGAQLDGKAR
>A0A354P0A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAKIPDLANNGSSSLKIICDFSPPRGGTPSLIGDLDGLNPDIVSVAYNPGKSVRVNPVAA
AAWIKANTKQDVVFTLATRDMNKVAIQSLLLGAQLLGLQNIVIVEGDGLSNRDRERFKAV
YDFQPTSLIESVRDMNQGKDFRGLKLRVATDFSVGATIDMGRPSDSEIPLAIRKAQTGAK
FFLAQAEFDPSVIARFRADFESHFDKGHAPPVFYGVQILAEDGIIFGNVPQGTRSELESG
RSGEE
>A0A6I4NYW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces sp. MMS17-SY077|TrEMBL
MTDPATDRGAEPDCPDFPVSFELYPPRTDAAALALGRTIDRLAETDPAFISVTFGAGGSD
RSRSLTVLQYILNATSVDAMAHLTCIGSSHAEANRLVREFLDAGITSFLALRGDPPAGVA
EEDVVLGDVASSAELVQLIHRVQQERQPFAQLGVPGNPGGRRISARPRPERVAVAAFPDG
HPRSRTSQQDIDALLAKEAAGANLAITQLFWHPEDYLGYVERARAGGVTIPILPGIMPTT
NPRRLVRLEELTGVPAPARLSIDLEIEPDPSVQFDIGVAHAAELARAVLAEGAPGLHLYT
YNRHEAALAVLARLGRVPARAS
>A0A850B9J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthonomonadales bacterium|TrEMBL
MDRVGDWIDRLRNNVAVADGAMGTLLSSRRVPLPYERANLIDPGVVEDAHAEYIAAGAQL
IETNTFGANRIKLSSYSLERQCLEINREAARIAIKAAAGRAAVAGAIGPCGRALAPSGAV
HPDAAADAFREQAEILIGEGVDLILLETFHDIDEMETAFRAVRSVSDIPVIVQKVFVEDG
ETLSAGLPERYAQRVSAWPGVVAIGANCAIGPQRMSQIIRAIASSTDVPVSAMPTPGLPQ
RVGGEIRYAVTPEYFGRQARTLVEAGASIIGGCCGTSALHIRAVAEALRDQAPRARTDIA
PVAASPAAPAVSAAPLSEYSELHRKLGKVYVKAVELDLPRGLDISVVLEGAEALRAAGVD
VIDISDGARARLRMSAMTVAHLVQQRTGAEVVLHFACRDRNLLAVQADLLGCHALGLRNI
LAVTGDPALIGDYPSATSVYDIDSVGLVRILRRFNEGLDLSGSAIGSATAFTIAVAFDPL
APDPNAEADRLARKRDEGAHMVYTQPIFDEQALDTAVSAARRVGLPLLFGLLPLRSSRHC
EFMHNEVPGIRIPEEIRARIADLSDGDARRFGLDVARRFLIRARGGTDGVYVMPPFGNHK
TAAAVLKALD
>A0A399GGD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria sp. MG1|TrEMBL
MHISQKLLQAREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDDALRDAYNAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDDVDELIDHLKEKVDAGGTF
IVTQMFYDTDLFLEWVKKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTRCNIPKHWTEAL
EPVKNDDVEVREVGKHLVAEMCRKLIDAGITHLHFYTMNLAQATRMVLEELDLLPDPESP
LEKPLPWRPSLALNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPMSIRDLSELFVRYMEGKLESLPWSEQPITTEAGSIQDDLIN
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEHISEIITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDVVDTWYLLNIVHNDFHATRGIFPIFDGLEVKDMDKPLVNPSVDL
PSANGDEATKVVNGGSHTNGTNGEQAEPHKEENPSLIDAAKAAAVEVTNGMRSLAMSN
>A0A4V2KS54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gramella sp. KN1008|TrEMBL
MKVTEHIKKANGKTLFSFEIIPPKKGKNIRELYDNIDPLMEFKPPFIDVTTSREEYVYVE
KDGLLDRQITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFTREETEYLLVDCHYLGIENV
MALRGDAMNHQKYFEASEGGHKYACDLVKQIRNMNDGKYLHDVIEADHKSDFCIGVAGYP
EKHLEAPSLQSDLKRLKEKVDAGADYIVTQMFFDNSKFFRFVEEAKKMGIDVPIIPGIKP
IAVERHLQILPQVFKIDLPEELIHEVEKCKTNAEVRQVGVEWCIKQSKELVDAGVPTVHY
YSMGKSSNIQKIAAAVF
>A0A2C9CGJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kuenenia stuttgartiensis|TrEMBL
MKSGSNLEKLLRDGKFAVTAELGPPRGADRTVIEKKAVMLKGYGDAFNITDCQTAVVRMS
SIAAGRIVLDSGVEPIVQMTCRDRNRIAIQSDLLGAAALGAKNVLCLTGDHQKFGDHPMA
KGVFDIDSIQLIQIVKALRDERLSQCGQELKAGSPAFFIGAAENPFADPFKYRAARLGKK
IKAGADFIQTQIIYNVNKFKEWMKMVTDMGLHEKTYILAGVAPLKSKGMAKHMKYNVPGM
DVPDEVMERMDAAAEAKRGKEEGIKICLEVIEQVREIKGVAGIHIMAVEWEEAVPEIVRQ
AGLYPRPSV
>A0A5C7JQW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium|TrEMBL
MTRILPSFQPMFADIGGDIAVSFEFFPPKTPAMEETLWTSISALAPLKPEFVSVTYGAGG
STRERTHNTVSRIARETDLKAAAHLTCVAATREEVDAVARDYWAAGVRAIVALRGDPIAG
IGAKYEPHPGGYESSVALIEGLKRIADFDISVSAYPECHPDSPSRIADVDFLKRKLDAGA
SRAITQFFFDPDAYLRYLDLVHAAGVSAPILPGILPVTNVAQLKKMAAACGASVPDWMGR
LFEGLDDHPTTRQLVAATVAAELCVRLYRRGVRNFHFYTLNRSELTRAICHLLGLRDVPV
HHVQGAAA
>A0A1F9KP69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFCSPLOWO2_12_FULL_57_22|TrEMBL
MKLCEIYSRPGPVFSFEFFPPKTAKGDEGLSDEIAVLKTLHPAFCSVTYGAAGSTRAKTV
ELVDRIHRECGLEVMCHLTVVGQSKDEIRSVLKRLMELGIDNIIALGGDPPQGVVDWEPH
PDGFHHSIELVREAVACRWFSIAVAGFPEVHPRAESRDFDLRYLKAKVDAGADVVITQLF
FDNEDYYRYVDDVRKLGVSVPIVPGILPVLSVPQARRFTVLCGSRIPPRLEQVLSRVEDD
DEGAVRLGIDYATEQCEGLLRFGVPGIHFYCLNKSRSVKAIFANLGL
>A0A363N3Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. WLB|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAIDLVRQINDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFNFVAKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>K0TG67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassiosira oceanica|TrEMBL
MCSAQDPAPDAKIIDLLSKKADNGIAHVSLEYFPPRTEQGVKNLHARMERMKTNTTALYT
DMTWGAGGSTAELSLDLALHAHRTGHVSNLHLTCTNMEKDGDPVKAVREALQAAYDGGIR
NIVALRGDPPEGSDEWTAAEGGFACALDLVRYIRKEFGDSFGISVAGYPEGHPNRISQLT
DEEAANMSDSEKGRCCTHDGITYVCKDDDYKKEMDYLKEKVDAGGDFIITQMFFDAEVFK
TFVKDCREWGINCPVVPGLMCINAYPGFKKMTKFCKTRVPKDLGEKMDAMKDDPDAVKKF
GVTFGSEICRSLLDSGVEILHFYTLNLEKVVYGITDDLGITSGLVEKSDEKDAKDMVAVG
SAWARVGDKVKGSAGEGVVKEMRKDGTAVIEVDGKDVEMAKGSYEKVFS
>R8ALX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plesiomonas shigelloides 302-73|TrEMBL
MSYHAHQLEALNQSVAELDGRINVSFEFFPPRSEEMENTLWQSIQRLSVLRPKFVSVTYG
ANSGERDRTHSIIKAIKEQTGLCAAPHLTCIDASEQELRCIAKDYWNNGIRQIVALRGDL
PAGQEKPALYASDLVALLREVADFDISVAAYPEVHPEAKSAQADLLHLKRKIDAGASRAI
TQFFFDVDSYLRFRDRCAAIGIDVEIVPGILPVSNFKQLTKFAALTNVRVPNWMQRMYDG
LDNDPATRNLVGASIAMDMVKVLSREGVKDFHFYTLNRAELSYAICHTLGVRPAA
>A0A2X0QZ70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrotoga fabula|TrEMBL
MEHAKSFSFEFFPPQTQEGAKKLAITCGELTVLKPAFFSVTFGAGGSTQDRTLETVQQIM
ADGYDAAPHLSCVGSTRENIRAILDLYKKIGVRRIVALRGDLPSGMAVFGEFHHASDLVS
FIRAETGEHFHIEVAAYPEFHPQAKSPQDDLRNFKRKVDAGANSAITQYFYNPDAYFRFV
DECHRMGVTLPIVPGIMPIMKFSQLARFSDGCGAEIPRWMRKVFEGYGDDSASVQAFGLD
VVTRLCERLLAGGAPGLHFYTLNQSRLSLEIWKRLETTCRVLF
>A0A1H1KI53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium GAS113|TrEMBL
MTQTKLSQAKPAKQANVPVSRLPGSNGVSVSFEFFPPKTPEMETALWEAIDRLAPLSPAF
VSVTYGAGGSTRERTHATVKRMIDETQLKPAAHLTCVAASRSEVNAIIRDYWAAGVRHIV
ALRGDPAGGAGARYEPHPEGYHWSTDLVTAVKAIGDFEVSVGAYPERHPESPTLFADVEM
LKRKVDAGADRAITQFFFDNDVYFRYLDVAQAAGITIPIVPGIVPVQNFKQTANFAKRTG
ASVPDWFAERFAGLDDDVATRRLVAAAVCAEQVLDLIDRGVTHIHFYTMNRADLVYAICH
LIGLRPALASDGTIEVAAA
>A0A014DA33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_6|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKAFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELNVLEELWNSLWQVT
TGKEFSPEIVRFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKDKLIPTVSIETRGTSSWKNWYLGAEA
>A0A849FWB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoreibacter sp|TrEMBL
MSRPNISFEFFPPKSLEASFRLWDAVQTLAPLDPSFVSVTYGAGGTTRKLTHEAVEALHK
TQGLRVAAHLTCVDATRAETLAIAQAYAEAGVTDIVALRGDPPKGADHFTPHPDGFTSSI
ELIAALKAQNDFTIRVGAYPDTHPEARDMDADIAFLKRKFDACADAAITQFFFEAETFFR
FRDACEKAGIDKPIIPGIFPIENWTKARSFAARCGAKIPTWLDDSFATAIRDDRHDLLAI
ALATELCDDLLQGGVEDLHFYTLNKPDMTRDICAALGVSPRVELAEVA
>A0A371JIL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnotalea glycerini|TrEMBL
MKIREYIKDKPLIFDGAMGTYYSEQQEGKCELANINNREHIIEIHRKYIAAGCVAIKTNT
FAANTISLEKDLELVKRVIAAGAQNAIQATDGREIFIFGDMGPIPYAGEGASPLCEYKEI
VDVFIENGIKNFLFETLGSDEYLSELSQYIKNKNKDSFIITQFAVTPDGFTRIGLSGKNI
VKRVEEIEEIDAIGFNCVSGAHHLYEYIKQFKTVQKYISIMPNAGYPTVRNNRTIFENSS
DYFAETLYKMAQLGVNILGGCCGTTPEYMRKTVDLMTGFKKPRRIEYKKQEIEENAETDK
ENGLIKKIGLGQKIIAVELDPPSKAEIAGFMEGAKRLKYNGVDAITIADCPLARARVDSS
LLACKLKRELDITPIPHMTCRDRNINATKALLLGLSIEGVENVLVVTGDPVPSPMRDEIK
TIFNFNSAILAKHISELNETVFDAPFGISGALNVNSRNFDSQLKHAQKKIDNGVSMLFTQ
PILTEEAFENLKRAREVLSAKLFGGIIPIVSHRNACFMNNEISGIKVSQEIINRYEGKTR
EESSELAVQISTDIAEKISNYVDGYYIITPFNRVEIVEKIVKKIKSL
>A0A6P2FP51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. PBS-H4|TrEMBL
MRLPLSFEFFPPKTPEGAVKLRAVRQQLYVQRPEFCSVTYGAGGSTHEGTFGTVREILGE
GVDAACHFSCIGATRTTVREQLKELKAMGVKRLVALRGDLPSGYGMGGEFHYASDLVGFI
REETGRDFRIEVACYPEVHPQARSPEADLQAFAAKVRAGADAAITQYFFSPEAYFRFVEE
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TELCARLASGGAPAMHFYTMNQSAATLALLERLGWKG
>A0A7Y9Z9N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter geojensis|TrEMBL
MALLNFRRKEAPANTPTAEVEALLRDYSIEVMPRTAEKVEDFTALLPAETRVYVAHIEGT
PIEDMVATAKRLNADGYKVMPHFPARIIKDRATLANWIAMYQGEADVKQALLLAGGVTTP
HGDFSDSMQLMETGLFDAAGFERLHVAGHPEGNRDIDATGTAGVDAALKWKNDFQTRTDA
KMAIATQFAFDAKPIIAWADSLREAGITLPVHIGIAGPAKLQTLIKFAIACGVGPSLKVL
QKRAMDVTKLLLPYEPTDVINELALHKAANPDFNISHVHFFPLGGIKTNASWAIENGGSS
AVPANTSV
>A0A1M6RCK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epilithonimonas mollis|TrEMBL
MKITDHIKNANGKTLFSFEILPPLKGQNIQSIFDSIDPLMEFDPAFIDVTYHREEYEYIE
RQDGLLEKRVVRKRPGTVGICAAIQNKYKVDAVPHILCGGFTREDTENFLIDLDFLGIQN
VVALRGDAVKTEIYFKPEKNGHHFAKDLVKQIREMNSGKYLDESIENCYPTEFCIGVAGY
PEKHMEAASFSQDIHHLKRKIEAGADYIVTQMFFDNHKFFEFVEKCREEGISVPIIPGIK
PLVTKSQLSMIPHRFKVDIPNELVIAVAKAKDNKAVKEIGIEWCINQSKELLNYGVPVLH
FYSMGKSDNILKIGREIF
>A0A430E446|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. ABOLH|TrEMBL
MTPTISDLEEARRALDAPLFADLAGDCAVSFEFFPPKTEKMEAALWETVRALEPLAPKFV
SVTYGAGGSTRERTHATVARIARETSMPAAAHLTCVEASRAEIDQVAQEYWAAGVRHIVA
LRGDPPTMGQKFVAHPDGYENAAALVAGLQKLHPFEISVAAYPECHPDSEHQAADLDNLR
AKIDAGATRAITQFFFTPEAFFRFRDAAAAAGINADLVPGILPVSNVAQVRKFAGLCGAS
IPAWMDRLFEGLDDHPGARQLVAATVAAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLM
GLRPKATPVAAAA
>A0A2S0NBP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phreatobacter cathodiphilus|TrEMBL
MMSSAYKPSRYVSRSRLKVSFEFFPPKTEEMEATLWESIERLAPLEPSFVSVTYGAGGST
RERTHATVSRIVKETALKPAAHLTCVAATKAQVDDVIRDYWAAGVRHIVALRGDPVGGVG
TTYESHPGGYEGSPELVAGIKAIGDFEVSVSAYPERHPESPSLETDIDMLKRKVDAGATR
AITQFFFDNDVYLRYLDRVRAAGITIPIVPGIVPVQNFKQTAGFAARTGASVPDWLARRF
EGLENDPATRKLIAAAVAAEQALDLVDRGVTEFHFYTMNRADLVYAVCHLLGMRPKDAAP
SAVAA
>A0A2E5MPD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium|TrEMBL
MDSQKQFKRRFSFEFFPPKTDQGKEKLQTVRDQLATVDPDFFSVTFGAGGSTRDRTIDTV
LDLHRQGISTAPHLSCVGATRDSIAELLDLYKENGIQRIVALRGDLPSGMGASGELRYAN
ELVSFIREHSGDTFNIEVAAYPEFHPQARNAEDDLKNFARKVEAGANSAITQYFFNPDSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSESIRK
FGEDMITEMCQKLLDAGAPGLHFYTLNQSTTSVNIWNNLGLGQRNKIAF
>A0A1E5RR32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hanseniaspora uvarum|TrEMBL
MKVDEKITKFQEDNSFEIPSFSYEYFVPKTLQGSYNLYERIDKMHKESNPLFIDITWNAG
GIINPSSSQKKKEISKFSGKIIPKTPQTNDIIDTTQQXLNLDSCMHMTCTNMTIKEIDTA
LKKAYNSGCQNILALRGDPPRETKPENSTTEEESTKPVKKYPFKYAIDLIKYIKEKYGDH
FCIGVAAYPEGHPEEKDADKLIGYLKQKVDLGATFIITQMFYNSDLFIEWCRKIRAAGVP
ESVHIIPGIMPITSYDSFLRRCNWCQIDVPSELNEVLKPVSQDDEALRTLATNYVAKMCL
KLFRSGYVKHLHFYTMNLEKGSFVILRELERLLGRRVLPLTSGVIANTNKENEIQPIFWR
SRPFTYVERKKKSKRDKSRRQXSFTGIENKSITPAPSSXASGSSSSSEFSDYDYEDDDEG
VNEHNFDSELIDDEFPNGRFGDSSSPAFGNLDLSLTQLIRQSESKSLSVWGTPTSMKELG
DLIINYLKGDLRSLPWCDTSVALEAKQLLRLLISLNQGGILTVNSQPKANGVPSSDPILG
WGPRLGYVYQKQYIEFLLPKRKLKDFLTLMNEKTTSTFTYLISDSQDEVFIYKGDDGQAR
IMASDVTKKXDIEKSAVLQKYSDQLPDFCKRMYCQCFHGCTKPTSVTWGCFPGREIVTTT
IVEKNSFLMWRDELFAIIKEWKNNFISISENPVSIKKEKPGKANAKNKHSESESEPALKK
QTVSKDDLSIKSSKSAKVLETVLDDYLLVSLVDNDYVSPGDLLLFTLLQLAD
>A0A7Y2G3V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinicaulis sp|TrEMBL
MSNLNVSFEFFPPKTDKMNESLWRSFNKLTPLRPRFVSVTYGAGGTTRSRTHDTVARMIK
KGAAPVAAHLTCVAATKNEVDDVLRNYWKSGVRHIVALRGDPPGGAGEPFTPHPGGYENA
AALAAGAKKIGDFEITVGCYPEKHPDSPSEAADIEMLKRKIDAGATRAITQFFYDNQAFL
RYRDRLDAAGVKIPVAPGIMPVTNFNGLRRMADICGATIPGRLVKLFENLDDDPSTRKLI
AATVAAQQCLELADEGVEDFHFYTLNRDELTYALCLMLGVRPDLSLQDAGEGAA
>A0A0J8DG11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium cylindrosporum DSM 605|TrEMBL
MVREYLLENVLLTDGAMGTYYSEITGDNVSKCEFANLKNPEVIEGIHKEYIDAGAKLIRT
NTFAANSITLGVSKNEVKKIIQEGYKIARKVAENKDVFVGASIGPIPEPRFDDEEFDLYD
EYIYIVDSFLEVGADIFVFETFSSLDYLKKVISYIRQRNSNAFILTQFSFTMDGFTRRGL
SLESVLSGVKLLDVDAYGFNCGLGPMHLYKILKGINMCSSIVSALPNAGYPDIINERSVY
VNNPDYFADMMVDIESLGVKIIGGCCGTTPKHISKIKEKLEFEGPSSFAVESVKIAEKKV
NIEKTSAFSKKVSDGNFVIAVELDPPFGVDISGIIDGAKLCKEIGVDLITVADSPRALAR
VDSLMVATKIKREVGIDVLPHICCRDKNINAIRSGLLASHIEGTRNILAVTGDPISEEDR
VSTKSVFNLNSFRLIELIEQMNKDVFQMDKIAIGGALNLNVTNKEAEIKRMDKKIEKGAS
FFLTQPIFDQEVIDYLINLKKDRKDAKILAGIMPLVSYRNAMFLHNEVPGILIPEECINK
FNKDMTKEEGYEVGVEIAASIANKLKPYVDGFYFITPFNRVEVVKRVIDKIN
>A0A6B0SE24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacterium bonnevillei|TrEMBL
MSLDISSTPTADEVGLLDEPRYELMPFDSFGEQMVHLPDGATIAITTSPTLGLDATIEWT
EEAAAEGYEIVPHIAARYVRDSDHLDEVAARLVDAGVTDIFVPGGDREEPAGEFDSALDM
LQALEDLEYSFDDVGITGYPEGHDFLSDETLEEAMAAKEPYATYVVTQLCYDPAAVVSWI
EQIRDRGIDLPVEVGIPGVMKYQRLLGISQKVGVGDSVRFLQKTSGVLGFIRQLIGSRGK
YTPDELVDGLAPYADDPTYDIRGLHVYTFNQVPDTETWRHKRLQG
>A0A830BNH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phtheirospermum japonicum|TrEMBL
MKVIEKIQQATAANDDRVVFSFEFFPPKTEDGVENLFERMERMVVHNPTFCDITWGAGGS
TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALTTIKSNGIQNVLALRGDPPHGQ
DKFVQVEGGFACALDLVKHIRSQYGDYFGITVAGYPEGHPDVIQDGAASAEAYQNDLAYL
KRKVDAGADVIVTQLFYDTDIFLKFVNDCRQIGITIPIVPGIMPINNYKGFIRMTGFCKT
KIPDEIMAALEPIKDNEEAVRAYGIHLGTEMCKKIMASGIKTLHLYTLNMEKSALAILTN
LGLIEESKISRSLPWRRPANVFRVKENVRPIFWANRPKSYISRTLGWDQYPQGRWGDSHN
ASYGALSDYQAHFHVQALTPSLHPNNIWDFFPFPWSG
>A0A317ISQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Melainabacteria bacterium|TrEMBL
MSHPFLKAIHEKPLLGDGAMGTLLYERGASTEGSFEQLNLSRPELVQQVHIDYLNAGADV
IETNSFSGNKLRLAAHGLDDQVWKLNVAAAKVARAAREVAGVPAFVAGAIGPTGKLLAPF
GETAEKEMSDAFQEQMEALLAGGVDLFIIETMSSLEETAIAIKTARRVAKLPVVAQLSFS
VEGHTLFGVQPEDAIKLVKDLGEDRPDVLGINCGAGPGPVFDSLLRMVAKAKSSRIDLKE
IFFSCLPNAGQPSLTAGRYQFMSRPDYCASYVEPYLRAGARLIGGCCGTTPLHIRAMREA
MDRYQASQVSAAAPGKVSASNKGGRQESALGSPKGHAEESVIGEGEVQEEKGKGTPGLSS
RLKLLKEKKAGDQFFISVELDPPKGAVTRKILAAASSLSDAGADAINVGDSPMARVRMSS
LATCQLISQKVGIDTIIHFTTRDRNLMGIQADLLGCQALGIRNILALTGDPPTLGNYVHA
TAVYDVDSVGLIKIITKLNEGLDIAGNSIGTATNLSIGCAVNPTFENRRAEVDRFRRKIE
AGAHFAMTQPIYQLSDWTDFLTEFGECLLPVLVGIMPLHSFKHAEYLHNEVPGISIPKRV
RDSMEKAGDEGARVGLELAEELLTEMAPYCQGTYLVPSFGRYDDMCGLVHRLKARYSKPV
FAGK
>A0A1R1FJL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL R5-0765|TrEMBL
MKADLRKVMQERVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFAELGARIIGGCCGTTPDHITAMKEALADYVPSPILEPDPSE
SKPRIVLHEHVDERSGRGGQPTIVDLVKHRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLEKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A1G2YP20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RBG_13_46_10|TrEMBL
RLSQALKNKSRFVIVAELVGGPNFSYEPIEKFLQAHKESKGKDIPADFDFVGITSPQSPG
GIANIEPADVHRFATSKNLLGELDFIPHISCKDMNKDGITSLLNTHKSTGVESILALTGD
KPVAAKGVFELESIGLLDLIGRLNNDALIKAKPEALQSVRQFFAGAAVSPFKYNEESQMQ
QYFKMEKKIATGAKFLITQVGWDWKKSTELMRYLADAKLDIPVIGNVYLLSTITPAPRLM
HDIKLPGCFVSDELFAKVCSEKVDQHIERAAQQLAMYRAIGAAGADVGGVPNYQTFIKIL
SRAAEIGNDWEQFKDNLCWPAKNAFYLYDDAGNKTKPAEFKKTVGHCLFNFMHWAMLDPE
HKGFHLFKKTMKFLGAEKGKGFVYRVFTAGEKTSKYFLFDCEECGDCFLPENFGQCTIGR
CEKGMNNAPCGDSTAEGKCGNNLDITCIGDLIYRAAASEKGGLEKLRKIINKPRNPALEH
TASILNYLFGKDHTARSPLIGIGELVHASIPKTGRIMKQLHELGENAFTEPSPELDYIKA
LIESQAVDGADYIAVNIDQFGESDPAFAVKLMTEYTKLVRKYGRGVPVCFDSSDDNVLLA
GLKEWYNTDEKVAPPLINSIKTYTIENMLPLKKHFDYKFIGLLLSSGKATDPSRTDTIDD
LYGLAKTLYDAAVNKYGFKPEEVFFDSTVFPLAIDMPMQPGVPSYTYRTFNTIKRIKTDE
QLKKCHFSLGITNSVRELPGRRIGVARAYTEVAMRYGLDAAILNPANQFGIKPADPELVE
LVEAYANMDGSNEKLNYAMKLMGQFCAKNRKAVS
>A0A327J8A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Melainabacteria bacterium|TrEMBL
MELKEIYQDYIASPDRRFLYNQPKISFEVFPPKDGNISDLFEQVRILKKYHPVLISLTYG
ANGGTKDMSFELLKTFLDLELNVMPHFTCVGSTRELIEHYITQIENMGIENILALRGDKT
EATPECEFNHANELVEFIHEHSTLSIGVAGYPECHIECENIHKDIENLKRKVDMGASAIF
TQLFFENDKLYRYIELVKNAGIDLPIVAGLLPIRSRKQVEKMISLTHAKIPNKIQEQLVK
FPNDAKKIGVEFAINQCHDLIDNKVDGLHFFTLNHSDQVSEILDNIL
>A0A1D2UJ06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. SCN 65-17|TrEMBL
MPAISFEFFPPKTDQQRAQLDRTAQLLKKAQPDYASVTFGAGGSTLSYTGETVAHLHREH
GLPVAPHLSCMGGTRAEIAALLDGYRAAGYRRIVALRGDLPSGMASPGDFRYAAELVRFI
REHSGDHFHIEVAAYPETHPQAEDALADLRHFQAKVEAGANGAITQYFFNPDAYFRFVDD
VRALGVTVPIVPGIMPISNFSQLKRFSDACGAEIPRWIAKRMQAHGDDAEAIAELSAQVV
AGLCRRLLEGGAPGLHFYTLNRARPTLAVLDLLH
>A0A1G5CVF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio hungatei|TrEMBL
MKVSDLYKEGKKTLSFEIFPPKKDKALEAIDETLDVLCELEPDFISVTFGAGGSAGSNNT
IEIAKKIKHNYGVEPVVHLTSLHYSKSEIDEFAAALQNEGIENILALRGDRNANIPEKDD
FHHASDVISYLKDKHDFCILGACYPEMHPETFSEEDELKNLKTKVDSGAEVLLSQLFFDN
EKFMSFREKSEEAGIEVPMIPGVMPVINAAQIKRMLTMCNATFPEKFKKITDKYEDNKEA
LFDAGMSYALSQIIDLLVSDIDGIHLYTMNNPVVARRICDGIKNILCRI
>A0A254S2X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWH1|TrEMBL
MKIVDILKQDKMSLSFEVFPPKKETSFESVKNATESIAALGPAFMSVTYGAGGGVSQYTL
EIAKNLKSKFGVPMLAHLTCVSSSKETVKQRIEDMKAAGITNVMALRGDLTPELIANGRT
DCDYHHAVELVRELKESGADFCIGAACYPEKHPESANQREDIKYLKEKVDAGADFLTTQM
IFDNNLFFNFLYKLREAGVTCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGIMRNVSAILGKNFIA
>A0A519SWB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp|TrEMBL
MKVTEHLRRAEGKTLFSFEVLPPRKGENIHTLFSNIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRKRPGTVGICAAIKNRFDVDTVPHLICGGFAKEETENALIDLHFLGIDN
VLALRGDPIKSEGQFQPHPDGHRYACDLIGQVAELNKGRYHDHDEQYQPAGAEPVLCTDF
CIGTAGYPEKHFEAPNHGSDIRFLKDKIDRGADYIVTQMFFDNEEFFKFEKRCRAAGITV
PIIPGLKPLTTKNQLIGLPRSFFLSIPEALSEAIHEAKDNTAAREVGIEWCLNQSRELMA
HGVPCLHYYSMGKSESIRRVAAGLF
>A0A430QW64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus|TrEMBL
MKIRDLLKARKGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRDRS
VLWAKRILDLGLNALAHLTVAGQSQEEVAGVLDRFVEAGVENILALRGDPPQGERVFRPH
PQGFRYASELVAHIRTRYGEGLSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRMGIEIPILPGIMPITSYTQLRRFTEVCGASIPGPLLSKLERHQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNRSPATRRVLERLGFKPA
>A0A1I7AR45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus amargosae|TrEMBL
MTRSVRELLASSRPTWSFEFFPAKTPEGEAQLWTALRQLERLRPSFVSVTYGAGGSTREG
TVAVTERIAAETTMTPLAHLTAVDHSIAELRHVVSRMAAAGVRNLLALRGDPPGADPQAD
WVKHPEGLEYASELVELIRSMGDFSVGVAAFPERHPRSPDFETDVAMFVRKCRAGADFAV
TQMFFRVEDYLRLRDRVAARGCDVPLIAGVMPVTNARQITRIVQLSGQAFPEELAARFAE
LDGDRPEDKAAVRAYGVEVATEMCRRLLDEGVPGIHFITMNRSTATREVFLNLTDADTGT
SVPSTLAATS
>A0A2V4KWY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas jessenii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A291IPR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas koyamae|TrEMBL
MNISFEIVPRSLAAFDEQYAFVQTLSGGINIINVPDIQRFDTRSWQLATRIDRNKYRFIP
HFRAIDFKIESGELFRIIEEYGLDSVLLVTGDPPEGLKRAFYNTDVVDLIRAVRSRFPEL
NIYAGFDPHRQGLQDECDYIWRKADAGATGFFSQPFYDPRMVEIYAEHMQGLETYIGISP
ITTQASQNYWEVKNRVKFPKSFRPDYDWNVEFANNLIATAAETGLHVYFMPIRIDLAKYF
QRIRFDTAQ
>A0A5Q0QJ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. dk4302|TrEMBL
MKIVEHIKNAKGKPLYSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYLYKQ
HSSGLLERVAYRKRPGTVAICAAIMSKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDSDFIPTVGGHAYATDLLEQVVDMNNGRYLHEDIEFSEKTDFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVNKYKEFVTKCREHGINVPIIPGLK
PLTTKNQLITLPRIFHLDIPEELSEAVDACKTNADVRQVGEEWLVQQCKELIEFGAPVLH
FYTMSNPGPTKKIVEKLV
>A0A3G7CD18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas chlororaphis subsp. piscium|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A544ZT98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Golovinomyces magnicellulatus|TrEMBL
MHIKDMLSEAESTRAPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGLEKVNDALHRAYKAGCTNILALRGDPPRNQET
WTATEGGFQYACDLVKHIRATYGDHFDIGVAGYPEGCDDNKDEDQLLDHLKYKVDMGATF
IVTQMFYDADNFVRWVGKVRERGITIPIIPGIMPIATYASFLRRANHMNVNIPKDWMELL
EPVKNDDMAVREIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRLVLEELEWTPCAERP
LQQALPWKPSKGLGRREEDVRPIFWRNRNKSY
>A0A2K0AW93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus haemolyticus|TrEMBL
MSRLLNQLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVESIHRSYIEAGVDIIQT
NTYGANFEKLRRFGLEHKVKDIHKAAVTIAKRAARPDTFILGTVGGFRSLQQEDLPLSTI
QYHAENQIDTLVEEGVDGLLFETYYDLEELTNIVTTTRRKYDIPIIAQLTASNTNYLVDG
TEINKALQQLVACGANVVGLNCHHGPHHMQRSFSHIELPETAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPQHIAYIKSSAKDLKPVKNKNVIPINRQT
NRAVTHTYKHNLTTKVKNGPTVIVELDTPKHLDTDLFFENIGKLDEANIDAVTLADNSLA
TVRVSNIAAASIIRQRYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMNYFITQPVYSKEKIKEVYEATKHLNVPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLSQFKAVKDDKEKTKALSLRLSKELIDTVHEYFNGLYIITPFQRIDYSLELAAY
SKAITQNKEAIS
>A0A0U0L2I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSCQTPSLSFEVFPPNPAVGNDNIILALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIELIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNEHFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>Q8DUN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mutans serotype c (strain ATCC 700610 / UA159)|TrEMBL
MSRLLDKLKTDILVADGAMGTLLYADGLESCHEYYNISHPERILAIHQAYIAAGADIIQT
NTYGAKRHRLKSFGHDKEVKAINQAAVHLARQAAGDNTFVLGTIGASHGLKHCELSLEDI
ISQTVEQARFLLETKQIDGLLLETYYDIEELEAALKALRPLTDLPIITNVALHEPGITEN
GRPLVEAFSNLVMLGADIVGLNCHLGPYHMIQSFKQVPLFAQSYLSAYPNASLLSFSSDD
NETPYHFSQNADYFEYCAKLFVEEGVRLIGGCCGTTPEHIKAIKRGIRGLKPIERKVTTP
LISQEDLIYEVEKKESLVDKVKKGITIIAEIDPPKTLAVDKFVDGVKALDEKGIAAITLA
DNSLARTRICNLSMASMLKDEIATPFLLHLSCRDHNMIGLQSRLLGMDLLGFDHILAITG
DPSKIGDFPGATSVYDATSFKLLSLIKQLNQGHGYSGASLKKATHFTVAAAFNPNVKNLS
RTGRLIEKKVAAGADYFITQPVFSETVIQELSEVTKPYEQPFFVGIMPITSYNNAVFLHN
EVPGISLSESFLAKLEAVKDDKETCQKVALAESKKLIDAILAHFNGIYLITPFLRYDLTV
ELIDYIQVKTATVAKKRT
>A0A496QKT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteria bacterium|TrEMBL
MKHNFVEHLNEKVILGDGAFGTYLFEKGVDLTKNTDLLNISDPDLVYSVHEEYIRAGSEL
IETNTFGANSFKMLRVGHEHKVREINLKGAELACRAAGNEIFVAGSIGPTGVNFPLENDE
VESGTVQEAFVEQMTALLEGGVGLFILETFTYLDELLLAIGTAKRIAPDIPIVAQMVYPF
HGRTAIGLDALDCGRATAAAGATVVGTNCGRGVKAMLSAVERLSSLKDAVFLSAFPNAGF
PEIVEHRMVYSTPPAYMADKVAEMVKFRVRLIGGCCGTTPAHIHEFRKHLHIKRHKTTRV
VTSVEKFSGLTEERKDSIGSGGMIESLRSDRIPVLVEVDPPRHLDIEGILTGARALAEAG
ADAITLAEHPLAVLRADNLSLAHRIREETGIQTVLHLTCRDRNILGLQAQIMGAHVLGLE
AILAVTGDPATSTDQPGVSGVFDVRSFGLVQMIDQFNCGLNMAGASMKKRTNFSIGAAFS
YHHVNPDLQISRLERKADLGAHFVMTQPIFDRDAVETMMERTQHLDLLIFTGIFPLISAR
NADFLHNEIPGISIPRKIRERLWKYEKVEDQRKAALDLTRKLIVDITPFAGGLYLISPLN
KWEIPLTLVQELRASGN
>A0A7X4GXK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella margarita|TrEMBL
MDNPNFSIEFFPPKTVEGADKLRVTRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILN
AGEQAAPHLSCVGGTRESIRAILAEFKSHDIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGDWFHIEVAAYPEVHPQAKSPQDDLLAFERKIKAGANSAITQYFYNADAYFQFVE
QTRKLGIDVPVVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTALCERLLQGGAPGLHFYSMNQAAATTALWQRLV
>G9XSJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfitobacterium hafniense DP7|TrEMBL
MEKTFREGKGIEMENRFKQSLLDPNTLSVTWELVPGRGAREKAQESALLAAEQAAKGGKV
HALTITDNPGGNPAILADYLGQEILKLGIEPLVHFTCKDKNRNQMESQLYALDRAEVRSL
LVMTGDYTVSGFKGRPKPVFDLDPTHTLELIAQMNEGLGIPGPKGMSYHQPSDFFAGAAV
SPFKGTEAEQMVQYYKLKKKVTSGAQFIVTQLGYDARKIHEVLQFMKLNDLNVPLVGNIY
ILPFGAAKIMNQNQLPGCVVTDKLLAEIDKERTAEDKGVSARLLRAAKMYALMKGMGFAG
VHIGGHNIKYEQVEYVIEKGEELSKDWLALVPEFDYPMPNGFYYYEKDPKTGLNTTTPVN
RKNLPLDAPVGVAYSGMRLMHSMLFTPGKNFFPVMRKIYKGRKDNRKHGLEHLAKVITND
CKDCGDCAMFELAYLCPMSQCPKNQRNGACGGSYQGWCEVYPNQKQCIYVRAYARLKKYD
EEGDLDSHHIPPANWDLYQTSSWSNFFLGRDHSGKILGIPTPEEEAKAKGADPAK
>A0A6N6VPZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Silvanigrella paludirubra|TrEMBL
MTKAAVSITPLLCCRSFRSSLEKGEYILLGGSTGTLLYEKGIFINRSFEEVNLSQPDLVY
QIHTDFINSGAQIISTNTWGANSLKLKSFGLENKIKEINTSGAKIARKAAGTNCWVAGTM
GPLGVRIEPWGPTSLDEAKDIFKEQASALIKGGVDLFILEGFPDLSEIHQAILAIKELDN
FPIIAMMSINEEGYSLYGTEPEWFIRKLDEWGADVVGVDGGNGPAPMIELLKKIKKSTTK
PIILYPNAGQPRMVDGRLIYMASPEYMGEFARQALLKGAQLLGGSSGTSPAHTKIMSGAI
RQAKAFDMTEHKVTDISDHPIHVHTTNVPRTLQSNWSQKIADGKFVVSMELLPPKGLEIE
KILERSKICKDNNIDAINIPDGPRASARMSSLATACIIEREIGIETVLHYACRDRNLLGI
QSDLLGASGLGIKNILCITGDPPKMGPYPNATAVFDIDAIGLVNMVTRLNSGLDLGGSSI
GRPTCMSVGVGANPVASDIEKEKSRFRYKVEAGAEWAITQPVFDSESLFRFLEFSSQFSI
PIIAGIWPLKSIRNAEFMANEVPGVYVPNKVLERMRKCKTADDQMEEGILIARELIEEIK
SSVQGLQISAPLGMVDFALKLL
>A0A820N556|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MASYEEDLRYLKEKVDYGADFIITRLFFQPATFIKFESDCRSIGIQCRIIPGIFPIQAYA
SFKNIVRLAKLDVPEEILACIEPIKYNGEAIRNFGVQKCVDLCRTLLDSGKIHGLHFYTL
NREYATIEILRKLDRCVRPKSYVHRTSNCEEFPNGRWGLPFAPSFGVLTDYHLFYIKIDA
TRDALLDEWGHELADKQDVRRMFACYIADEKNGRVKIVHHFPWKDEDISSETNFIHDHLI
KYNRKGILTISSQPAVNGKSSTDSIFGRGIKKWLCLSKSLFRIFTSEKNIPALRAALKKF
PGVNYHFVNKSGEVNETSTEGEQPIALIWGVFAAREIIQPTVVGPISFMIF
>A0A5K0WAH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nymphaea colorata|TrEMBL
MKVIEKIREAAKEDRVIFSFEYFPPKTEDGVDNLFERMERMVAHNPAFGDITWGAGGSTA
DLTLDISNRMQNM
>A0A327L5N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoplanes roseus|TrEMBL
MPSPTEPRASRVPHRREDLRVSFEFFPPKIEEMEKTLWDSIERLAPLRPNFVSVTYGAGG
STRERTHATVKRILDETALTPAAHLTCVAATRDEVDDVVRGYLSAGVRHIVALRGDPVAG
IGTAYAPHPGGYVNAADLVGGIKRLAAAEKTDIEVSVSAYPERHPESPSDTVDLDMLAAK
VDAGATRAITQFFFDNELYLRYLDRVRARGITIPIVPGILPVQNFTLTRSFAAKAGASIP
SWLADRFAGLEDDAATRKLIAAAVAAEQVFDLVDRGVTEFHFYTMNRADLVYAVCHLLGL
RPAAAPAAEARAEAAA
>A0A0R2UCL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR92 bacterium BACL26 MAG-121220-bin70|TrEMBL
MTNAPHLSFEFFAAKTQQGAENLHVTASQLNKFSPELFSVTYGAAGSTRDTTKDLVLSLH
NQGYQAAPHLSIGGDSDSDVLKLVDSYKKAGIKNLVALRGDLPSGVGATKKLVHANQLVA
LIREHSGDHFNISVGAYPEIHPEAESYSNDIYWLGEKFKAGADRAITQYFYNPEAYFNFI
ESCARAGIDKPIIPGIMPLTNYENLVRFSDNCGAEIPRWLRWQLKERSHNSADLISYGVE
MVSELCEKLLAGGAPGFHFYTMNKWQISDQICRNLGFSTKD
>A0A3S4L6I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus viridans|TrEMBL
MTKQTPSLSFEVFPPNPEVGNAKLLRALENMQELAPHFISVTASNNKYNIKETTVALANH
IQNELSIPTIAHLPAIYLSKEKVADTLHELDQVGVHRILALRGDIIPGIEPLKDFRYATD
LIEFIKTEAPHFDVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVHHATKALFEHQPKLEVI
>A0A503AL78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-6-2|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDTVIREFADMGVKRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKNAGDFDISVSAYPEKHPESPDFATDIDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHETEAA
GSAAA
>A0A545A2C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Golovinomyces magnicellulatus|TrEMBL
MEKITDKIAALPPGSNYFSLEFFPPKTSMGTSNLRSRLDRMARALQPLFVTVTWGAGGST
ATNSLELADLCQRQLGLTTCLHLTSARVLGIRNILALRGDPPRKDTETMNSEIKSPADFE
WAIDLVRYIKKNYGDFFCIGVAAYPEGHADGSDPDGQSLESDLPYLIEKVKAGADFIMTQ
LFFDTEAYDVFEKRLLEHESGCFKNLPIIPGLMPIQSYQMIMRTLKLTHVKMPSDMMADL
TSIKGDDELVKKAGVDIVSKIVSHIQDSPAPPIGRRGFHFYTLNLEKAVSFILERTSLLR
LSHSAHAIDNFISDCTNINSSVSPPKSNVNDHTDHLQHQQSPITSDSSNTVVNTSPLTSR
PQVEVTLSGINILSNYIENRASTLAISEGRDALGREATWDDFPNGRWGDARSPAYGELDG
YGINIHLYLNQAIRLWGYPQSTNEITSIFTNYIKGSLDAIPWSDEPICRETDIIKDQLLK
VNEKGWWTIASQPAINGINSNDDVFGWGPRNGFVFQKAFVELFLSSEDFLYLQTKVKTSD
MADKISWYACNSKGEFLSSDAPMKSCFNNRGSINAVTWGVFPGKEIVTPTIIEEISFRAW
AEEAFKIWAEWGKAYTSSSPTSPDFQKAQASHQLINRLREEVWLVNIIHHGLVEKDGLWD
LLIG
>A0A1F0TM81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. HMSC073D09|TrEMBL
MKVSDFLNKKAAAKAISFEVLPPLKGNGTAQLFRTIDRLREFCPNYINITTHNSEFVYRQ
LDNGQYERDRIRRRPGTIAIAAAIQQRYGIPVIPHIICSGATIESIEYELLDLQFLGIQN
LLLLRGDKARDEQLFTPTPNGHTHTTDLIEQVNRFNAGFFADGTAMKHPGESFEYGVACY
PEKHEEAPNLDMDIDYLLKKQQLGAKYAVTQLFYDNQKYFGFVEKARQKGVTIPIVPGIK
PFAKLGQLTVIPRTFHCDLPTALASEIVKCKTDDDAKALGVEWATQQCRELYAKGVPSIH
FYTVSAVDSICEVAKKLL
>A0A4R6LH45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. P3160|TrEMBL
MKVTEHIENAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
VMALRGDAMKDEQYFMPKAGGNDYAVDLVKQISLLNQGKYLHEVMDADNRADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFNFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDSCKNNAEIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASHLF
>V4LNQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eutrema salsugineum|TrEMBL
MKVVDKIKSVTEEGKTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGSTA
DLTLEIASRMQNVICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEADGLATLESYQSDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNHKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAFGIHFATEMCKKILAHGITTLHLYTLNVDKSAIGILKNL
GLIDESKISRSLPWRRPANVFRIKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYGTLSDYQFMRPRARDKKLQQEWVVPLKSIEDVQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLGKINSNGFLTINSQPSVNAAKSDTPAIGWGGPGGYVYQKAYLEFFCSKEKLD
TLVEKSKAFPSIIFMAVNKAENWVSNIGQSDVNAVTWGVFPAKEIIQPTIVDPASFRVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNDYINGDIFSVFA
>A0A7V6ZD37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetomicrobium hydrogeniformans|TrEMBL
MKIKEIFEKKKFVFSFEIFPPKPTTPLDRIYSTLDDLKGLSPDFISVTYGAGGSTRDRSP
QIAIDVKNVYDIESLAHLTCVGSTRDEVVGVVDHLLGSGVHNILALRGDPQQEAVSPFVE
GDFSHAIDLVKFLRERYGEKIAIGGAAYPEGHIECDDPIKDLHYLKQKVDAGVDFLVTQL
FFDNELFYRFIERTSIVGIEVPISAGIMPVVNKNQIERIVTLCGASLPKKFVRILHRYAD
DPRSLEEAGIAYATDQIVDLIASGVRGIHLYTMNKAHVARKISSNIEILREGFVNDKNSE
GALL
>A0A6Q2XZJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Esox lucius|TrEMBL
MLPAGKYITCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTESGDHWF
SLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLESVLHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPIGTDWEEEEGGFNYATDLVK
HIRCEFDDYFDICVAGYPTGHPEAQSYDEDLKHLKEKVDAGADFIITQLFFRADTFLKFV
RDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKENDAAIRNYGIE
HAVGMCRMLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVE
DVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKM
WGEELTSEKSVYEVFTSYIMAEPNQAGHKVMCLPWNDEPLAPETNLLKDELAKVNRRGVL
TINSQPSINGKPSSDSIVGWGPPGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHI
VNVQGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYE
DESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDVNPLEQPVEQAAEQFI
QEQSAN
>A0A160NX78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces laurentii|TrEMBL
MALGTASVRPDRARTVRDILASGGTSYSFEFFAPRSEKSEQSLWNAMRRIEAVAPSFVSV
TYGAGGSTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNVLGRYADVGIRNMLAVR
GDPPGDPLGEWVAHPEGVHYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADYAITQMFFDPEAYLRLRDSVEKAGCDTPIIPEVMPVISVKTLERLPVLSNAAF
PADVKDRILAVKDDPAAVRSLGIEFATGFCARLLSEGVPGLHFITLNNSVATLEIYENLG
LHQQS
>A0A5C4T428|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus hemerocallicola|TrEMBL
MLKQKISNKQPGILTYGITPPKLNTVSEKVAEISQKQIERVRGLGLDGLIVYDVQEEADR
VEEERPFPYLQTIDPNDYCKTYLHQLDLPKIIYRCVGKNTEAQFSEWVGSDTEEDRFSVF
VGASSSKQKVQMGLTDAYRLARSLNGNLTMGGVVIPERHIAKKDEHLRTVTKANNGCKFF
VSQATYNVDASKNFLSDYYYHCRHHQIEMVPILFNLAPCGSQKTLQFMKWLGISIPRWLE
NELIHSNDILDKSLALSRDIFAELFDFGMEKGIPIGCSVESVSTRKVEIEASIQLVNEIK
TILGKSVVHSQ
>F9XHC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymoseptoria tritici (strain CBS 115943 / IPO323)|TrEMBL
MDKITDKIAALPPNANYFSLEFFPPKTQQGFSNLNARLSRMAHSLRPLFVNVTWGAGGST
SAKSLALAEVTQRELGLTTCLHLTCTNMSRKLIDEALEQAKVLGVRNILALRGDPPRSDE
YRDNSLPNADEDDSNKDFTWAEDLVRYIRKQYGDYFCVGVAGYPEGHSDQSCPEHQSMEH
DLPFLVEKMKAGADFIMTQLFYDVEAYERFERRLREHESGAFKTVPLIPGLMPVQSYQIL
RRTTKLSHAALPEEMLKRLHAVKGDDEAVKRVGVDVLSEMVEGMKSRKGNGPQGFHFYTL
NLEKVVAQIVERTGLIPPEEKKDENAVADDEVGDFVLVDKDVKQKQRRRKSSMANSQSRN
RVIVARTRASSNSSTRTSAAHEVPDDEAGIPREKINSRSNTLAISEGDGALGREATWDDF
PNGRFGDARSPAYGEIDGYGVSLHVSVPDAKRLWGEPKTIEDISTSFRRHLSGEIEAIPW
SEEPLQNETLTIKDQLQSLINRGWWTVASQPAVNGVRSTDPVHGWGPKNGFVFQKPFVEF
FIPASDWSALQGKLVEHPQITYFAGNANGDFVSSGEDTVNPVTWGTFAGKEIITPTIIEA
VSFKAWCEEAFGIWAEWQRVYKPGSESSRLLERIRKEYWLVSVIHHGFLEEGALWKDLLE
A
>A0A7W0C9E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosalsimonas propionicica|TrEMBL
MKLKQALEKKQFAVTTEVQAPIEQESEDLVKSLNLIRGRVDGVSLSEVEFQGIVGDTIKT
CQTLKENRFESIYQTTTRDKNRIQLQKDLISAHHAGIENLLVFTEDYRITGDSLQEMMFF
HVDAGKLQSVLQHFRDGRGIEGQEIEVQPNFCLGSGVEASWGKNVPDLELKEMEEMTKMG
AGYFLTTPVFDVERFDKFMSRTNTFGVPVIAEVLILRTAGMARFLNRHLKSGLVPDWAIQ
KLAKATDKDKASIELFADTVKGLKDLCDGIHIITIGGEDKLRHYLDAAKLR
>A0A354U9S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaeria bacterium|TrEMBL
MKKEEQLSRQLEMNFSGHSKGNLFREHLANAEFSVLLELHIPGRDSKLESVVSKYSELES
VAMSPRNFPGGLAFLDDSPDFPSLDPGEFAAALCKTGRDRHLIYLNGRDRTQEDIDYNLG
IYRFEGFKNIVAVSGAAGSTLEDAVKHRYYDSANILQRNACSKEPLFAGCVANPFKYTRT
DSILQYSKLNKKIAAGAQFVVAQSGWDMRKLLEMRWCMFRRSQNIPTIARILYLTPEKAE
DICSGKCPGLWISDDLKRAIRKEMMYSLAQFEAAQWRRLQIHAAGAKFLGYSGIQIAGVD
DPETANRIYLRIQEAMSEFSNYDDWRAAHNDYYSKVEMVPYPYRYYLFENMLAEGVTCDT
AKVNSEPLPECSFAERFRYRLARFLLPHADRMPAEDKRLTKRLLAACHRNCDSCHLPQTM
YVCTGNCPKLLNNGVCGESRPSGDCPYTGTECIFAALLRRAELDNDYSVLDENIIC
>A0A410P2T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Velamenicoccus archaeovorus|TrEMBL
MKTKDFKEILKTKVLVCDGALGTVFYERGLSSGRPCEYLNIARPEAVLALHREYVDAGCD
IVQTNTFAANKVRLSVYGLQNEAEAMNLAGARIAREAAGNRDIFVAGSIGPLGRFPLEQD
LSQEDVRAIFKEQISALLAGGVDIFVLETFQSLRELRLALDVCRSVSSLPVVCQMSFQEN
MGTAFGEDMHQVVRELEAGGADVIGANCGLGPAHILEAARRLVSLSSGYVSAQPNAGYPQ
VVEGRTYYLTTPDYFAQYALTLKEIGVNIIGGCCGIAPAHIRLAARAVKGAAPMSRSSET
FILHQPRIAGRDRISLSSEKKSSGIADLVGRDRFTVIAELLPPKNADIRKMEAAADLLKA
GGADVISVPENPLGQSRMSSLMAAACVKERTGLEAVSHFTCRDRNLIGIQSDLLGAHALG
LTGLLAVTGDPVGLGSHGKATNVYDLNAIQLITLIENMNRHMGLNMCVGAAFNPNAKNID
AQISYLRRKVDAGARFVMTQPLFEASRILEIHDRIKSAGVPVFYGVLPLVSSKNAEFLHN
EVPGISIPEEIRRRMRIDDREMAVREGEAIAMEIIESVRGRVNGIYLVSPFGRYDVSARI
IKALSVRRDAPSFPGQAGGVK
>A0A1V2AXN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Flexibacter] sp. ATCC 35208|TrEMBL
MKGTLQHKINSGKSGIVFYSLTPPKITTESEKVTIIAGGQIDRLKDLEIDGLIIYDIQDE
SLRTDKERPFSFIPTISPEIYSKELLATLPVPKIIYKSIANHTREMFADWLSRNTDLEAT
VFVGASSQQQLQATNFSLSDAYQVKREMGLDILLGGVAIPERHTKKGDEHLRMFSKMQNG
CNFFVSQCIYNINETKNVMSDYHYHALSNDTRPAPVIFTLTPCGSLKTLQFMEWLGIEVP
KWVYNDLKYSKDILQSSIHTATNIAGEILNYAASKNLPVGFNIESVSNKKDEINAAHEIL
ENVLHLVKPMRNEVAGAKKAVPAY
>A0A2V5IDG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus violaceofuscus (strain CBS 115571)|TrEMBL
MHIKEKLSQNEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPVEKVDAALQAAYKAGCTNILALRGDPPREKEN
WEATDGGFRYAKDLVRHIREKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDNFIDWVKKCRNKGVAVPIIPGIMPIQTYAAFIRRSEWTKTRIPPDWLEAL
EPVKNDDAAVRNIGKRLVADMCRRLLESGLNHLHFYTMNLAQSTQLVLEDLNLLPSEETP
LQRALPWRPSLGLNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGQPKSIRDITHIFVDFLEGKLARLPWSDSPITTEANAIKDDLIE
LNKKGIFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLIPSYLLDDLIARIEKNG
YLTYHAVSKNGNLRTNTNDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQSVVDDWCLVNIVNNDFHNTSSLFDLFKDLNVKDLDTEIAVEDGETK
VHQNGVTNGVEATNG
>A0A139DTH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Adiutrix intracellularis|TrEMBL
MSRELKSNSNLEKVLVAGHFAVTGELGPPRSADVHEVEEKSKHLKGNVDSVNITDNQTAV
VRMSSLAAGLILQRTGTEANMQMVCRDRNRIAMQSDILGAAALGINNLLCLSGDHQKFGD
HPQSKNVFDVDAINLIAMVKTMRDDRRLLSGQEIPDGAQPKLFIGAAYNPFADPEDYRVL
RAAKKVAAGVDFLQSQCIYDMLRFKKFIARAVDMGLTEKAYFMAGVTPLKSLGMAKYMKN
NVPGISVPDALIERMKGVAKDKQVDEGIKIACEQIQELKDTKGVAGVHLMLIEWEHMVPR
MVQEAKLNPRPKV
>A0A1S9M357|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. SRS-W-1-2016|TrEMBL
MSPPSLIDTHPNLTGAAPVALSYELFPPRSPAAAESLWTTIGELEATDPDFVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAEIIGELLDNGVRGILALRGDLPKD
SGQPVSGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSVEHDVEVLL
AKQRSGADFAITQVFFHTEQYADLISRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAPELIERLAAADSDAERRKIGVRATVDLANAALQAGAPGIHLYTFNEHACALDVLDKLA
LPRPARPASRLSAIARRQELVS
>A0A1E5XIG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia insulae DS-56|TrEMBL
MSTDYTDRPSRRRPDERPKFQVSFEFFPPKTDVMEERFWDSIHKLAPLHPRFVSVTYGAG
GSTRERTLRMVSRVKADTGVDAAAHLTCVGATRDEVDAVVRGYQEAGISRIVALRGDPAE
GIGKPFTPHPDGYRNAADLVAGIRKIGNFDISVAAYPEKHPQSPNWEADIDNLKRKLDAG
ATRAITQMFFDNDDYFRLVDRAQAAGIAAPIVPGIQPIHSFKQISGFAARCGASIPGWVA
ERFEGLEEDPETHALVASAVAAEQVLELVDNGITEFHFYTLNRSNLVLALARLLGARPD
>A0A6I3MC30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. MC2016-06|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKNIQELYDNIDPLMEFQPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
IMALRGDAMKDEQYFIPKAGGNDYAIDLVKQISLLNQGKYLHEVMDIDNKANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDKCKNNVEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A139CR90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanolobus sp. T82-4|TrEMBL
MSLTFKDKLESDHFLITAEISPPKGTDLSEALADAELIRDQVDALNVTDNQRAVMRMSPL
AVSRALLDAGHEVIMQLTCRDRNRLALQSELLGAYSMGIRNICVMTGDHTTKGDHPGARP
VYDMDSVQLLDIVRRMREGYDLAGNTIDNPPVFTVGAVTNTDPSKLMQMMKLRKKAKTGL
DFIQTQAVYDTGQFQTFMEKTEDIEVPIIAGLIPLKSAKMARFMNQNVPGINVPDEIIER
IENAERPVDEGLAICAETARELRKLCRGIHIMPIGKHDKTSQILEMAGIRKNI
>X0XUA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MIHHIQNKIYHVEVLPPKQDSEKLEKDLEIFSNKYLRVMGSGYCVCITDNAMGLLSFQGT
EMIEELDLPVTPEQVMIHLTTFHTKDDLDNILDICKSKGIRYLLIVTGDGSERLPKLKPS
DVGATDVESVTSVELLKYINREYPDTFVLGVAFNPYEPEEHEFEKMERKMKAGATFIITQ
PLIEKNEVVDRLLKKYPEIPVIVDAWMSRKLHLLSEAVGYEIPENTEFDPISTLKMLHKL
YPEYG
>X1WU92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acyrthosiphon pisum|TrEMBL
MTNVRIPLWMSKMYEGLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYA
ICHTLGVRPGV
>A0A0F9XI85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MNNPNKPVISFEFFPTKTDAGHEKLIAAAHVMAAEKPEFFSVTYGAGGSTRDRTLNTVLQ
LDQEVKVPTAPHLSCVGDSKADLRSLLQQYRASGIKRIVALRGDLPSGMGQASGELRYAN
ELVEFIRDETGDHFTIEVAAYPEAHPQARHFEADLENFVRKAQAGADSAITQYFFNADCY
FNFVDRVRKAGVDIPVIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASISS
FGTDVISRMCERLLEGGAPGLHFYTLNQAEPSLAVWRNLHASSHSN
>A0A851HI55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micrococcaceae bacterium|TrEMBL
MSPSNTDTSAQALMHDFSLEMTGKDVDAVREAAPLIPQGTRINVTFLGNEDLEMRVTAAK
AVKDLGFVPVPHISARRIESEAELKEFLQALADVDAAKHVFAVGGDPAQPMGPYGSALEM
IESGVFPEFGVEEVSIAGYPEGHQHMADDDFLRETQHKLSALTEQNLSSGIITQFGFDID
PVATWLNELAAKDITAPVRIGVPGPAGIRRLLKFAKRFGVGASAGVALKYGFSLTNLIGT
AGPDKFLNELASTTQETNFQGDVSVHFYTFGGITNTAEWVKDFTENL
>X1UXL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
NRLSLQAELLFAYTRGIRNVLCLTGDSVVVGDHKEAKGVFDLDSTQLLMTIRQMEAGKDL
GGNELDGAVEFCAGAIVTPEANPIEPQLIKFEKKVEAGAEFFQTQAIYDLDKFAKFMEHA
RQFPVKILAGIILLVSARMAKYMTENVPGIFVPQNLIDELADAPKGEAINKGIEIAGRMI
ATLEKESICDGVHVMAIGREEVVPDILKAAGLAT
>A0A1S1TFJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. LCM 4573|TrEMBL
MKSTGVREAFGISFEFFPPKSDEMEVQLWDTVEKLVSWDPDFVSVTYGAGGSTKAPTIEA
VRRLIHETPLATAAHLTCVDASREEVRSVVEEYRATGVRRIVALRGDPTGGIGTAYEPHP
EGYTDTADLVRALVEFGDFDISVSAYPEKHPESPDLSADIETLKRKADAGAHRALTQFFF
DNDIFERYLEKVAAAGITIPVVPGIMPIQNLTQLKRFARRCGSSVPSFLDDRFESYDDKP
EERAEIAADIAAEQIDDLMRRGIRDFHIYTMNRAPLVSAVLERLGRRRVEEKAGAAA
>A0A3N4AS40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SSM44|TrEMBL
MNQTIINKPISFEFFPTKTDAGHAKLIAAGHALAAEKPEFFSVTYGAGGSTRDRTRKTVL
QLDSEVKVATAPHLSCVGDSLEDLRTLLGEYREAGIKRIVALRGDLPSGMGQASGELRYA
NELVEFIRQETGDHFTIEVAAYPEAHPQAPHFEADLKNFVRKVQAGADSAITQYFFNADC
YFHFVERARKAGVEVPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLESYGDDSQSIS
SFGTEVISQMCERLLEGGAPGLHFYTLNQAEPSLDILRNLQTG
>X1P1P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MIRKISDILREKERTYSFELFPPKTPRGREKLPETAGILKELQPDWFAVTYGAGGTTREL
TMDIVDELQKRFQIPTMHHFTCVGHSKAELEAIIKKMKEKNICNILALRGDAPEGVEHWE
PAPDGLEYCYQLIELIRSYDSFFSIG
>A0A0F9QUB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MTEKMVYSKLGELIAKGEFVLTGELEPEKTCDLSHTIQEAREMAPYVVAANVTDSPLAIV
TINSMAASAIIQRETGLECVWQLTVRDANKIGLAGQIMGAEALGLSNVLSLTGDHTALGD
CPETKPVFDLDSATLIKLVREMVDTGSINGHEIEIPPKFHVGGAANPNADPMEAEILKIG
RKAEAGAEFLQTQVVYDIDMTAEFLREIKKYNVPILLGIFPMKSYGMAKGFDMFVPGVSV
PKEILERWKRVKTDVSDKKEQKEIYDQLNYEFFKPFIIELKSKGLITGVHCMAVKYTRFY
PKLIEVIKKL
>A0A3M6YZC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGVRNILALRGDPPRSDE
YNDPNNPLSEQDDSNRDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLVEKTAAGADFIMTQLFFDVEAYNDYEKRLRSHESGLFRTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLSRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTL
NLEKVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSS
NRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPINSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLQGEIEA
MPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSNDPIYGWGPKNGFVFQKPF
VELFLPSADWQRLKPILQSDDQVTYYAGNAAGDFQSSDENSVNPVTWGTFAGKEIITPTI
IEGDSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDA
LIAA
>E9END5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075)|TrEMBL
MHIKDMLAEAEKGGQPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLDKVNAALQKAYKAGCTNILALRGDPPRAQEK
WTAAEGGFHYARDLVKHIRATYGDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGKVRERGINIPILPGIMPIATYASFLRRAKHMQCKVPDHWMTAL
EPVKNDDVAVREIGKTLVAEMCRKLLANGIYHLHFYTMNLAQATRMLLEELTWAPCAERP
LQQALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTTVQDIASIFVKYLNREIESLPWSEAPLTGEANAIKDNLIQ
LNKRGLLTINSQPAVDGVKSSHPIHGWGPSNGYVYQKAYLELLVPASIFTEMVKRVEDKP
TLTYYAVTKDGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGTDW
AHCFESETPSRVLLDQIMNEWYLVNVVNNDFHENQTIFDLFEGLEVNGLDTPVAV
>A0A1G4G6L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrimonas mucosa|TrEMBL
MKISELIYQDPKPVFSFELLPPLKGNSIRQVFDTIDRLKEFGPKYINITTHHSENIYKED
EKGIIRKMNVRRRPGSVAIAAAIQNKYGIRAVPHIISQGFSKEETEYALIDLSFLGVTDL
LLLRGDTKKLDADQRKLDCHQYATGLQEQVNNFNKGIALDGSSFPPPEVPFSYGMACYPE
KHEESPNMESEIFYTKMKVQNGADYLVTQMFFDNRKYFEFVDRCRAEGIGVPIIPGIKPI
HLKNQLNVLPKIFRTEIPEELARELRQCNSDADAVEVGVEWCLLQCRELVRRGVPGIHFY
ALGATESIYRVAREIY
>A0A1E8S5C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC069C10|TrEMBL
MTTVHPALSFELFPPRSHASCESLLHTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSNAE
LHRIGVDYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQSLSELEY
V
>A0A1G3QW43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium RBG_16_49_21|TrEMBL
MDLQESLKKKRFVVTSEIQPPLEEDFRELLENIEKIRGRLDALTVPEFDFEGVIADSIGT
CSILRENKFNPILQTTTREKNRLDLQSFLVKASEKGVKNILAFTEDYRITGDSLQEIMFF
HVDSGKLFSVLENLRDGHDVTGKDIRKAAEFFVGSGIDANHNENIPDLELKEMEEMVKLG
TGYFLTTPVFDPEEFRKFMKRVEPFNIPVIAEVILLKSASTAHFINRHLKKGLVPAHIIQ
KLTRAPDKEKASIEIFTEIIKGLKDICQGIHLIPLGWEGKIPKFLDAVKL
>A0A4Y9S950|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia arenosa|TrEMBL
MTDPNFSIEFFPPKTAEGADKLRIARGKLAELRPKYFSVTYGAGGSTQQGTLDTVLEILA
EGHAAAPHLSCVGGSKESIRAVLEQFKSHGIHRLVALRGDLPSGYGGAGEFRYANELVEF
IRAETGDWFHIEVAAYPETHPQARSPQDDLQAFVRKVQAGANAAITQYFYNADAYFQFVD
AARKAGVDVPIVAGIMPITNTTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTQLCERLLAGGAPGLHFYSMNQAAATTAIWNRLVTPQ
>A0A2M8AU09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desantisbacteria bacterium CG_4_9_14_3_um_filter_40_11|TrEMBL
MSKQFKDVLASGEFVITSEIGPPKGTNIEKMLHHIEILKDKVHGMNVTDNQSSVMRLSSV
AVCHIITDHGGEPILQMTCRDRNRMALQSDLLSAYVLGVRNVLCLTGDHISLGDHKGAKQ
VFDLDSVQLIAAVKSLEAGQDIGGNKLDGGVEFCVGATATPEADNMDSQFLKFRKKIKTG
AGFFQTQAVYDMVKLKAFMEYARQSDVKILAGILVLVSAGMARYLNANVAGVTVPQELID
EMAGAEKGKALQKGMEIAARQIKQIKDEKICDGVHIMAIGKEEVVPEILSMSGV
>G2YUL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryotinia fuckeliana (strain T4)|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHHIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAAL
EEVKNDDAAVRNIGKDLVAEMCRRIIEAGVHHLHFYTMNLAQATRMVLEELSLTPSNQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLESGIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHEP
DLTYYAVKKTGDVQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLNEPFETSESGD
VDGVRFIEPQTVPLTNGEANGH
>A0A3G2I682|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola subsp. Rhopalosiphum maidis|TrEMBL
MNFVNQYHQDIIKKKLENLNNTVQCSFEFFPPKSLDAEKKLLSSALKLSELKPFFFSVTY
GANSGEREKTYNVVKEIHEKTGVKTAAHLTCVDSTLNELKEIAKFYWENGIRSIVALRGD
APKKLYQHKIYALDLVLLLKKIADFDISVAAYPEIHPEAKNAQSDILNLKKKVDAGANRA
ITQFFFNVESYLRFRDNCIKNNINIEIVPGILPIYNFEQLKKFSSMTNVSIPKWMFKMFH
GLEGDLKAQKIIGASIVIDMIKVLSDEGINNFHFYTLNQSDVVYSICHMFGFKN
>S0JIB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. 14-2|TrEMBL
MKISELLRTKEVTISCELFPPKKGSELAKAHEVVREMARVKPAFMSVTYGASGGISEHTV
DLANEVQNVNGVLALAHLTCASSGRDKIQEVLGELQNRKIENILALRGDIPADLDFPLPN
QYHHASELIEEIKAFGDFCIGGACYPEGHPEADSVEADIEYLKQKVDAGCEFLTTQMFFD
NNILYNFLYRALKKGIEVPVIAGIMPVTNANQIKRITSLSGTALPARFRAIVERFADKPA
ALKQAGIAYATDQIIDLIANGVNNIHIYTMNKPDVAGAIFQNLSEIYIPGQEPEDGRNQK
I
>A0A3M7ARJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGVRNILALRGDPPRSDE
YNDPNNPLSEQDDSNRDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLVEKTAAGADFIMTQLFFDVEAYNDYEKRLRSHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLNRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTL
NLEKVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSS
NRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPVNSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLQGEIEA
MPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSND
>A0A7I8EBL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jeongeupia sp. HS-3|TrEMBL
MTRPPISFEFFPSKTPEGVEKLRNTRRQLAQFKPEFFSVTFGAGGTTQDGTRNAVFEIQS
EGHQAAPHLSCIGSTRSTIAELLTSYREHGIRRIVALRGDIPSGMVDVGEFRYANELVAF
IREQHGDWFHIEVAAYPEYHPQAQSAEADLRAFVGKVHAGADAAITQYFFNADAYFRFVD
EVQGRGVSIPIVPGIMPIQNFSQLSRFSDMCGAEIPRWLKLRLASFGDDSASIRAFGLDF
VTELSDRVLSQGAPGLHFYTLNAAGAVSTVCQRLGF
>A0A3A4QL45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MPVFTPGRRWQPPYLPFKREPFNRRALATIEKAIKGPLFGCRMCGNCLLQETAFICPMEC
PKGERNGPCGGSTKEHCYVDETRPCIWYKIYERSFNMGREEKLLEVLPPLDWDKVGTETW
GDVLGRVKEMGVGRALNGLLLKPAEIRYKTWDNIFEPIREPSWWQGDNQYHPPKYTEPVS
ELERRLKAGEFVITAEVAPPVSCKTDKMYKHIENIKPYVAAINFTDNPSATPRTASWACS
KMALEKGAEPVMQIAARDRTRVGLQSEVMGAADLGIRNMLCISGDSMKMAPQPRGRMDVI
DIDSLQMLWILRRMRDEGRYMDGREIKTPPQYFLGAAASPFASEPKFQALREHKKINAGA
QFFQTNLVYDVEHMEIWLNELAKRNILDKIYILIGITPLKTFKMAKYMNDEVPGVSIPLR
LMLRMEHAEETGKAQEEGLMIAFELIEKIRKFKGQGVHGLHIMAVGWEDIVPRIVTEANL
LPKGFQKPEPELEKAPA
>A0A7Z9HEX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lambdaproteobacteria bacterium|TrEMBL
MHLIELYKKKDFVFSIEIFPPKTAKGMEKLKTTLEAFKSCTPDYFSVTYGAGGTSRENTH
ELAAHIHHDLDVPAMAHLTCVAHTVEEIDVVLSNLKNSEITNVMALRGDPTAGTKHFVQP
KGGYHYASELITAIREHSDFGIGAAGYPEGHVENPDKDDDRKHLHEKIAAGAEFVITQFF
LENTHFLRWRDQLRREGVNVPLVAGILPPSNWKATKHMSEMCGVSIPEDLAQALIKNETD
PEASREIGFDHVENQFEELLQEGVEGVHLYALNRLSTVERLGPILKDASGTISTPHL
>A0A419YZC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. BL23I1N1|TrEMBL
MNPIELSFEFFPPKTQEGVEKLRATRAQLTPLKPMFVSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFAHKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTDLCQRLIDAKVPGLHFYTLNGAAATKAICERLGA
>A0A7C9HQS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus sp. HMF7620|TrEMBL
MSRISVELVPRSRSGLKAELAEVKAHLSEVDTVNIPDLTRYSLRSWAGCSFAGPGLTSIP
HLRAVDFNPREPLPFLPLLEAHGIEEVLVVTGDAPVDMSAKVYDVDAVDLIRRLSREAPH
LRVYAGLDPYRQSFVRERNYLERKLDAGACGFFTQPFFDLRVADTWGDLLPDGTPVWWGA
TSILTEASFNYWRARNHAVFPRSFTPTLACNRTFARDLLHFARERGQHAYFMPVKVKVLD
YLGGLLSGQQERRPRQEAVWNASL
>A0A7J8KCV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rousettus aegyptiacus|TrEMBL
MVNEPRGHGSLNPRLEGSSSESSKDSSRCSTPGLDPERHERLKEKMRRRMESGDKWFSLE
FFPPRTAQGAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLE
TILHMTCCRQSREEITGHLHKAKRLGLKNIMALRGDPIGDQWEDVEGGFCHAVDLVKHIR
SEFGDYFDICVAACFPAYSSIKQRRDIY
>A0A800JAI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lambdaproteobacteria bacterium|TrEMBL
MIPGADCWETIEAANGIQAAGKQAIPHIAARSFSGPEVLNKCLSGLQDAGIKRVLLIGGG
VPEPAGEYASVMDLLKTGLFAEYGINSFDFAGHPEGNPDDPNSEHHLLEKLRWTADREIS
ARIVTQWSLDAKKTNNWISDLREKGVSNPIHIGVPGPSTVKTLIRFAKVCGVKASTQVLR
KQGLNISKLMFFNKPDKIISELNGYDQLHLYPFGGIAKSAAWLIEWQNINH
>A0A1U7LVH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neolecta irregularis (strain DAH-3)|TrEMBL
MRISDKLQTGLPTWSFEYFPPKTNQGLQNLYDRMERMYELGPAFIDITWNAGGRLSNLTC
EMVATAQSVYGLETCMHLTCTGMPQEKVADALKSAYEAGCQNILALRGDPLREEEEWKAT
PGGFKYARDIVRYIKKKYGDYFCIVVAGYPEGHPDEPEEDKDIQHLKEKIDAGGSLIITQ
MFYDVDKFLLWVKKCRNAGITCPIIPGIMPIQTWAAFIRRAKWAGCHIPQHFMEQLEPMK
DDDAALRERGTVLIMDMCQKIFDAGIQHLHFYTMNLEQATKMVLEGLGLVPSKESLSPLP
WRQSLSLRRKEENVRPIFWKNRVKSYVARTEHFDEFPNGRWGDSRSPAFGELDYYGIGLK
CSSEVAIRQWGTPTTIAEIAELFAKYCLCEIKSLPWSDVPISAEANSITQDLVKLNKRGF
LTINSQPAINGEKSSHQVYGWGPRNGYVYQKAYLEFFVHPSIVNNLVSALSRDPYNSFYA
VSKSGDLKTNTLSDGPNAVTWGVFPGKEILQPTIVEPVSFLAWKDEAYRLGSDWAKCYPA
NSPSRKLINEIMDTWFLINIVHNDYHNSRAIFEIFESLDIITLMAYGQAVICDPTNALLY
TNRANAYLKIKKYEDAVTDSRKALELIINDPGSQMKANYFLGQAQLELGHAEEAAKSLRA
AHDLAIKVHSPSVEAISASVIRAKAVVWEMKEKARIQRSSDLYLFLENVLQEKRDHHVAQ
MHERAHRKIYTKEQLLDKIEEIDVVWRRQIDDMSEVFTRADHQRTESMRIPDYLICPISF
ALFKDPVITLPGISYDRSSIMHHLKMYSTDPISRAPLKLSDLRPNIALRQAVEDFLEKNS
WAADF
>A0A7Z9I2W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lambdaproteobacteria bacterium|TrEMBL
MHLIELYQKQDFVYSIEIFPPKTEKGMEKLKITLEAFGSSAPDYFSVTYGAGGTSRENTH
ELSAYIQHELDVPAMAHLTCVSHTAKEIDDVLTKLKNSKIENMMALRGDPTAGTERFIQP
KGGYRYAVELITAIREHSDFGIGAAGYPEGHVENPDIDNDRKHLHEKIATGAEFIVTQFF
LENTHFLRWRDKLHHEGANVPLVAGILPPSNWKATKRMSKMCCVNIPQDLSESLIKYENE
PQTSREIGFEHVEQQIDELLAEGVEGVHLYALNSLETVKRLGPKLRDAASTSSSLPAD
>A0A6P0QCH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcoleus sp. SIO2G3|TrEMBL
MSDTIQNSRLKADTVSQPPQLYSNGTTPVQNRFRNAVQSGEFLITAEVCPPKGGDPTHMI
QMAQTLKGRVHAVNITDGSRAVLRMCSIAASVILLQHGIEPICQMACRDRNRLALQADLM
GAYALGIRNVLALTGDPVKAGDHPDAKSVFDLESVRLLQLITKLNEGSDSNDKPLTDGVT
DLFSGAAIDPQLKSWSGLQSRFERKLEAGAQFFQSQLISDFERLEKFMDNIAAGTNKPIL
AGVFLLKSAKNAQFINKYVPGVDIPQTTIDRLAAADDPLQEGVKIAAEQVQLARQLCQGV
HMMAVRREDLIPKILDLAGILPVKA
>A0A1I0EW28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] aminophilum|TrEMBL
MKIIDILNKKKTTLSFEVFPPKKIENFDSVQQVTEEVAALKPSFMSVTYGAGGGTSEFTL
NIAKNIRDKYGVEVLPHLTCVSSTKEDVHQMLRKIQANGFDNIMALRGDIPKDGAPHDDY
HYASELIEDIRAHGDFCIGAACYPEGHVECSHKNEDIKNLKRKVDAGVDFLTTQMFFDNA
EFFNFLYRLRENDIRVPVLAGIMPITNAVQLSRSVALSGTSVPTRFREIVDKFGDHPAAM
KQAGIIYATEQIVDLIANDVRHIHVYSMNKPDIAEAIQKNLSEILKV
>A0A1Q5D8G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB01249|TrEMBL
MGPVADRPTYSFEFFPPRTAQGERTLWQAIRRLEPLGPDFVSVTYGAGGSSRDRTIEVTK
RLVTETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPKGEWTAHPDG
FHHAYQLVELVRSLGDFTIGVAAFPERHPRSADWDSDIRHFVAKCRAGADYAITQMFFDV
EDYLRLRDRVAAAGCTTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAQHRPDI
AYEIGVAHATLMADRLLAEGAPGLHYITLNKSTATLDIHRNVMSTRSLHAS
>A0A4Q1K7S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium stagni|TrEMBL
MRVTQHIENAQGKPLFSFEILPPLKGQNIQSIFDGIDPLMEFQPPFIDVTYHREEYEFKE
LENGLLQKKIVKKRPGTVGICAAIQGKYDVDAIPHVLCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKTETYFKPEKDGNHYASDLVEQISNLNRGIYLDEDLKNTAKTNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNQKFFEFVDKCRKAGIEVPIIPGLK
PIATKKQLNLIPHRFSLELPDSLIMEVVRAKDNDAVKQIGIEWCIAQSKELLAAGVPVLH
YYSMGKADNIKSIAKEVF
>A0A3A8HEV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus sp. CA054B|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTVEELAPLEPGFVSVTYGAGGSTRDRTV
DLVTHIKEKTGIEAMAHLTCVGHTRDELRDVLRRLDAAGIENVLLLRGDPPQGQTTFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETVSREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRVGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVGALKGRS
>A0A1Q5MYI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB00455|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVRATEQIASDTTLTPVAHLTAVDHSVAELRNVIGQFADAGIRNMLVVRG
DPPGDPMGEWVAHPEGVHYAADLVRLVKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSAEKAGCETPIIPEVMPVVGIRQLDRLPQLSNALFP
ADVKERMLAVKDDQAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>C1E728|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)|TrEMBL
MSAKQVRRANVRSPLPKPPTHPSVGTDDVHANNRLPPHFPTPKAARVFLERSPYVSWRAQ
RPVFAHPAFNGVIHPDLPVWAGEPGIPEPAVGSDAATPRISRLAKTEVDILPDFHVQTVA
ASRCRSAAEARQRIAAASDAGASAILMVTGDAPDAARGARTTRSAWDSTKLLREAFAMRE
RGEVHEDVTLACVANPSLEGAARDPTARLRAKLDAGAEMVVTQPAQLAPAVHRAWWDAVR
SESLHRECDVVFGVTYLASHRSVRRWQRLCGLSGDASSDATEEAEETARLWEEMERSMDA
TTFERWRDERLDLAVAAALADVDARGVHVMPVTEEGYAGVGRVADAIGALAARAR
>A0A7L3MI97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Horornis vulcanius|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDSDRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVSAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7T6AQ81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus oligotrophicus|TrEMBL
MQIPQLIHNRSPFVSLEFFPPKKQEQWPAFLEAAGELGRLQPLFVSVTYGAGGSTQSNTL
EICEQLIRTCGFEVMPHLTGVTADTGKIDGFLTAVKALGIDNVLALRGDRPTGYSGTDAE
LFAAFPHAADLVAYIRRHHPELAIGVAGFPEAHAEARSIAEDLTVMCQKVECGADFVITQ
LYFDNRVYFDYVERLRALGITVPVIPGILPVRNLTSLRFVLEMCNARIPGRLINALTSAH
EEGGADAVYEIGVAYAREQIKGLLDGGAPGVHLYTLNQADMCLAVMDGLL
>A0A6G1NTJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium dahliae VDG1|TrEMBL
MDKITDKIAALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
AFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPPRKAE
YQDAVDEESDDDEDFVWATDLVKYIRKNHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVEKTQAGADFIMTQLFFDIDAYDHFEQVLREHPSGAFKTIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDALMARLDAVKGDDEKVKEVGVDIVSELVDQIRAVKSKRTTGPQGFHFYTL
NLEKAVSFILERTNLIPDKEQEDEEAVIDDATTPPVVPTVQINGLHPGSHHRPGRRQSSI
GSDPHNRVIVSSASNHAYETNPEGAGLPAEPINTRANTLAISEGEGVLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVTQAVRLWGHPKSSEDISTLFIKHIRGELSAIPWSEE
GLSPETNIIQEQLIELNTRGWWTVASQPAVNGVPSRDATFGWGPSHGFVFQKAFVELFLP
AADWKVLSERLTGPEVEGTEIITPTIIEEVSFRAWSEEAFKIWGEWSRVYGRGHESEKFL
KSVKDEYWLGNIIHHDFVETNALWDLLRG
>A0A6A0A7S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haematococcus lacustris|TrEMBL
MKIVDKVNECIAKGQTVFSFEFFPPRTEEGVENLFDRLDRMAAYGPVFCDITWGAGGSTA
DVTLDIAKRMQNVVCVETMMHLTCTNMPLEKLDSALAEVGTWMGRCQ
>A0A7G5LHZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp. MC521|TrEMBL
MLDDNLRASRKTAETRPDLQISFEFFPPKTDVMEERFWESVHKLAPLKPRFVSVTYGAGG
STRERTLRMVSRIASDTGVPAAAHLTCVGATKAEVDEVVRGYKDAGVTSIVALRGDPPEG
IGQPFTPHPEGYQNAADLVAGIRKIGDFDISVAAYPEKHPQSESWDVEIDNLKRKIDAGA
NRAITQMFFSNADYLRYVERAQKAGITAPIVPGIQPIHSFKQISGFAGRCGASIPEWLAE
RFDGLDEDPETHALMAAAVAAEQVTELLDEGITEFHFFTLNRSNLVLALARLLGRRP
>A0A8J6MXZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfacyla euxinica|TrEMBL
MKLKESLDKKRFVVTSEIQAPIDEEPEALIKRLEMVRGRVDGVAVPELEIEGVVGDSIKA
CNLLKQNRFEPIYQTTTRDKSRPHLQKDLLLAHEAGVENVLTFTEDYRITGDSLQEMMFF
HVDAGKLASVLEHMREGYTVDGKELPSKAEFVLGSGVESGWGKNVPDLEMKEMEEMTKIG
TGYFLTTPVFDLARFEKFMNQAKTFGIPVIAEVMILRTAGMAQFLNRHFKSGLIPDWVIK
KLAKAPDRQKASLEIFADTVEGLKDLCQGVHIITIGGEEKLKLYLDAAKLR
>A0A6G4CS46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKNIIGE
YNYAFELIEKIKANNNFGVSGACYPEGHIECESLKQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLSKTQQKNINVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKKA
MEDAGIAYAVEQIVDLASSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A1M3FXH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium 46-32|TrEMBL
MKVIDHIRQAKETLISFEVLPPLKGKGIEALYNHMDPLMEFRPAYINVTYHRSEHVFKKR
ADGGFDKVVVRKRPGTESICAAIMNKYDVDTVPHLICGGFSVNDTEDALLNLQYLGIDNV
LVLRGDAAKNETAFEPEADGHKYASDLIRQVVNLNAGVYLEEDLKSTSKTTFCIGVAGYP
EKHFEAPNMETDLRYLKAKVDAGADYIVTQMFFDNARYYAFVKACREAGITVPIIPGLKP
IYTRKQLTVIPKTFHIDLPTDLSNAILKCKNDEEVEKVGTEWLLAQSRDLKKNGVPVLHY
YTLGRPMMVAEVVKNL
>A0A352WH76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MIEKNGKKIEFSCEVFPPKRNEDMYEIYKTLDEIKLLGPDFISVTYGAGGSNSKRTAQIA
TYIENICEIRALAHVTAVGVNPEKLQDMLQELKKKNVTRILALRGDKPRDMTEEDFEARH
YKNASDIIKIIKNEGGFKIAAACYPEKHPEAESVEKDIEFLKYKVESGANELITQMFFDN
SKFYDFMDKLQAAGVNVPVHAGIMPITAAKQLGTSVSLSGSSIPTTLSNLIAKYTDDPVS
MRKAGIEYAIKQTEDLVANGVDGVHIYCMNKSDVTRQIYEAVLYDLA
>A0A422QID9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia aurea|TrEMBL
METPDFSIEFFPPKTPEGAEKLRIARAKLADLNPKYFSVTFGAGGSTQQGTLATVREIQA
AGHEAAPHLSCIGATRESIRDVLKQYQDSGIKRVVALRGDLPSGYGGAGELRYASELVEF
IRQETGDWFHIEVAAYPEMHPQARSPQDDLQAFARKVGAGANAAITQYFYNADAYFQFVD
NVRKLGVDVPVVAGIMPITNYMQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTAIWQRLRA
>R6YIC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:94|TrEMBL
MKIKDLLQQSDRKVVFSCEIFPPKKDVEFSGIFETVDAIHQLGADFISVTYGAAGSTSKK
TVEVASYIQDTHHIPALAHLTCCSSTREEIHQRLEEMKARGIENILALRGDRPKEFVPGP
YTYAIQLIQDIKAQGDFCVGGACYPEGHVECPHKEDDIYYLKEKVEAGCDFLTTQMFFDN
NVYYNFLYRVLAVGIKVPVIPGIMPVINAKQVKRSAELSGAMMPPRFLAIADKFADDPLA
MEQTGIAYATDQIIDLVANGVRHIHLYTMNRPKTAAKILENLSHILR
>A0A4Z1KTG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrytis porri|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHHIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAAL
EEVKNDDAAVRNIGKDLVAEMCRRILDAGVYHLHFYTMNLAQATRMVLDELRLTPSNQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLETGIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHEP
DLTYYAVKKTGDLQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLNEPFETSENGD
VNGVRFIEPQTVPLTNGEANGH
>A0A5S9M719|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus safensis|TrEMBL
MRKKKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPG
IKLSDSIRDIMAKAGEDKEKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTT
YIHQKEKESNVHVNYH
>T2PJN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis JCP8017A|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNATGVFNHASDL
VSYIRSQRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A351TI40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MPVGLIYETLNSLKKLSPDFISVTYGAGGGKNNVETLRIASAIKNDYGLESVFHLPCIGL
TKGEVLQKLSELKSVGIENILALRGDIPEGFTSAGDFRHASDLISFIKENGDFNIIAACY
TEGHIEATDIAEDIRNLKIKVDAGADQLITQLFFDNDYFYSFMDRCLSADIHLPVEAGIM
PVVNKKQIERMATLCGATVPKKFVTMMERYENNPAAMRDAGIAYAVDQIVDLIAQGVSGI
HLYTMNNPYIAGKIYEAVHNLIV
>A0A4Q3RQL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacteraceae bacterium|TrEMBL
MSPHRRVIGPVARSAERPNRKLGISFEFSPPKTPEAEENLWKAIRRLEPLQPDFVSVTYG
AGGSTRDRTHRTVKRIVEETSLKPAAHLTCVEASCSDVDQVIRDYWDAGVRHLVALRGDP
PGSIGGEYVPRPDGYANATELTRAVRGIQPFEVLVGVYPEGHPESPNIQHDIDVLKAKVD
AGATRGITQFFFEIDPFLRFMEKVRAAGITIPISPGIMPVSNFKGLVKMAGACGAGIPGW
LG
>A0A350M623|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
YVDPTRPCIWYRIYDRAFKMHREEMLLEVLPPLDWEKTGTETWGDVVFQVKKVGIKKFVS
GMFEKDKEKREEKWQSVFEPVRQPEWWQGDRNHHPAAYEEPVSELERRLRNGEFVVTSEV
APPATVKITKLKENINLIKPYVSAINFTDCPSAAARMSSWACSTIAIGEDAEPVMQIAAR
DRTRVGLQAEIMGAAALGIQNVLCLSGDSMALAPPPRGRMDIVDLDSVQMLWLLRRIRDD
GHYLDGRPIKFPPKYFLGAAASPFASEPKFQAIREEKKVNAGAQFFQTNLVYDVDGLEKW
LNELAIRNILDKVYLLIGVTPLKSYGMASYMHNEVPGVFIPETLLNRMKTAGDGASEEGV
QIALELIEKIKKLEGVNGLHLMPVMWESIVPRIVTEADLLPKDFVSPAPDNQKEIS
>A0A2H1HSP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei CIP 102111|TrEMBL
MVESTAVRLLEDFSLEMTGKDVGNLQEAASAIAPGTRINVTYLGNEDLPMRVAAAKAVGE
LGFTPVPHISARRVTSEQALRDFLAALAEVNATERVFVVGGDPATPEGPYPDSLSIIRTG
ILQEYGVREVSVAGYPEGHPDIDTATLWEHLRAKTASLAEQGLSQVVISQFAFDAERVSE
WVAEVRDAGVTGDIRVGTPGPAGVKRLIGYAKRFGVGTSAGIIKKYGFSLANLVGTAGPD
RFITELAADTQVAGDGRGVKTHFYTFGGLSATAEWIRDFSRGA
>A0A2E2EP61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVIKHLENAKQTLFSFEILPPLKGKSIDSIYNSLDPLMEYNPPFIDVTYHREEYVYKNR
KDGLLERISVRKRPGTVGICAAIMNKYNVDTVPHIICGGFNKEETENALIDLDFLGIDNV
LVLRGDPIKSETYFNAEEGGHKFASGLLKQVDGMNNGVYLDEELKNSAKTDFCIGVAGYP
EKHFEAANMRSDIHFLKKKVEAGADYIVTQMFFDNQKYYDFVKLCRENDINIPIIPGLKP
MSTEKQLTLLPQRFHLNVPNELVDEVLKCKSNEDVRQVGVEWAINQTKELIEFGAPCIHF
YTMGKSDNVQKIVGNFV
>A0A2A2G511|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria sp. WN036|TrEMBL
MTPRPTARPAPPSLSYELYPPRSAASADTLLRTIEELEPTRPDHVSVTYSGDEQRRDSSL
ALLDHLLARTSLRPLAHLTCVGSTRAELEQTVAALVRRGVRGVLALRGDLDPGAEPGELR
HAGELVELVREVEQRHTAALAAGRLAVGVAAYPTRHPESPSFRHDVEVLLAKQRSGADFA
ITQVYFRPQRYERLVAAARAAGVTIPIVPGIMPVTDPRRLRTLCRLAGLAPHPGLAAALE
DAPGPAERHRAGVAFAARLARAALDAGAPGLHLYTFNEHGAALDLLEHVDLPRVPHVPVA
LEDLLLPA
>G8ZNU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Torulaspora delbrueckii (strain ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866)|TrEMBL
MSIKELYNEKSRPSLSLEFFPPKMEAGKRNLLERMERMSALDPLFITVTWGAGGSTAEKT
LELAALAQRNLNLPVCMHLTCTNMDRTIIDKALHKCQQAGIRNILALRGDPPVGESWNQN
NTQPAEFQHAVDLVKYIKSQYGSYFCIGVAAYPEGHCEGEAEANQQNPLKDLPYLKEKVD
AGADFVITQLFYDVDKFLAFERLYVEHISTEVPLIPGLMPVNSFLLFNRAAKLSHASIPK
YILDKFPEEIQHDDHAVKSICVRLLADIVDRIYNDTQGRIKCFHFYTLNLEKAVAQIVAE
SSTLRYILTQAEEEDAENMADQVGDIALYDDASETNQTTDRKRRRHSSNVSAEVITNRVV
AGKPRRRSVGMPSRKIAISISQGSGTLGRDATWDDFPNGRFGDSRSPAYGEIDGYGPTIK
VGNKRALEIWGSPRNNIDLKNIFIKYLENSVDALPWCDLGLSPESALIQEELIQLNDRGF
LTLASQPATNGSSSTDKIFGWGPANGIVYQKAFVEMFVSKQRWDQGLKGIIDHYGSEKLS
YYVGDSNGNFDTNLAPESSNVVTWGVFCNSQVIQTTIISEDSFKAWRDEAFNIWLEWAKL
FPKNSPSNSFLKQMHQDYYLVSIVHHDYIQPDELWEILLG
>A0A556W317|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp|TrEMBL
MKFDDEPVPGYSLPILPGHTSPGRLERVLRAGKFAITSELDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYSTILQISCRDRNRIAIQGEILGAAAMGAC
NLLCLTGDGVQAGDHPQAKPVFDLDSMSLLEMARTMRDESRFQSGRKLTSPPRLFLGGAA
NPFVPPRDWRPHRTAKKAAAGAQFIQTQYCFDVPLLREYMAKINDLGLLEGPERIFILPG
IGPLASARGARWIREHVPGVHIPDAVIKRLEGADDQKEEGKRLCMDLLQEIREIPGVSGV
HIMAYRQEHSVAEIIEKTGVLEGRVPWYPGRDNPAELNPESPDASENARVSA
>A0A3D8T3I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus mulundensis|TrEMBL
MEKITDKIAALPPGANYFSLEFFPPKTQMVGLYSSPHSAGFANLQARLERMAQALRPLFV
TVTWGAGGSTAARSLELAEICQRQLQLTTCLHLTCTNMSRTLVDQALEEAKVLGIRNILA
LRGDPPRSEEYNMHGEDDSNKDFTFAVDLVRYIRQKYGDYFCVGVAGYPEGHPADSFQGT
QDPKVDLPWLVEKTQAGADFIMTQLTYDIDAYTNYENMLRNHESGAFKTIPIVPGLMPIH
SYKILTRVTKLSHVKVPPPILAKLEEARHDDDAVKRLGVDIIAELVDGIRKLPTSGFRGF
HFYTLNLEKTVSFILERCKLIPDYDDDAEAVTDGVSLLTVDAAKATRRRRASSISSLPHN
RVIVDKVSDGSSNVSITHEATAASAGLPAGPPDRNTTLQISEGLGALGREATWDDFPNGR
WGDARSPAFGEIDGYGPTLHVAPSVAHRIWGYPVSPDDISKLFRRHVSGDLHMVPWSEGG
AEENTSGLNAETETIRPELLALIDKKGWWTLASQPAVNGVRSDDPVFGWGPPGEGFVFQK
PFVEFFCPSSDFTNTLKPLLRKHGHEKLAWFATNAAGDFESSLPADTSDTEPVEMNPNNV
NAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAYRIWDEWRRIYPRNSATERFIEKTKNDVW
LVCVVGQDFGAGTETGSAEEEDEKKFMWRLLANC
>A0A1Y0FXK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrio sp. PSBB006|TrEMBL
MTDSQPRLSFEFFPPKTPEGKQKLIHVRDQLNSFAPDFFSVTYGAGGSTRDNTKGIVTSF
KSAGIATAPHLSFGGDDEETILELLQDYKAAGVDRIVALRGDMPSGVGGAYQLVYANELV
AFIRKHFGDHFHLEVAAYPEIHPQAKSYSDDIRYLKGKFDAGANSGITQYFFNPDSYFYF
MEQCHKAGIDQPIYPGIMPIINYRNLTRFSDTCGAEIPRWLRKALENFGDDDASLKSFGV
DLVSELCEVLLENDAPGLHFYTMNQTEPTAQIVSNLGLIPTE
>A0A2T6C5W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kordia periserrulae|TrEMBL
MKVTEHIAQSEGKTLFTFEILPPLKGQDIKSIFDNIDPLMEYKPPFIDVTYHREEYTFKE
LENGLLKKQVVKKRPGTVGICAAIQNKYSVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKAEKEGHRYASELVSQIQDLNNGKYLDEELQNSSATDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKAGAEYIVTQMFFDNQKYFDFVEKCRKEGITVPIIPGLK
PIATRKQLNLIPHRFKVDLPDDLIMEVVRCKDNKAVRQVGIEWCIQQSKELVAAGVPILH
YYSMGRSSNIEAIAKEIF
>A0A166RKS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum tofieldiae|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTAMGLSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKDE
YRDTEDSDVDDAEDFVWAVDLVKYIRKNYGDYFCIGVAAYPEGHADESHPLGQSFEHDLP
YLVEKVQAGADFIMTQLFFDIKAYDKFEKVLREHPSGAFKDIVLLPGLMPIQSYQMIKRT
TKLSHAKIPENLMARLDAAKGDDERVKQVGVDILSELVEQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDPTFEDEEAVIDDGPGVPVSIPAVQLNGLSPVHPAARALSGRRH
SSMGSSDPHNRIIVSSASNPAYETTAAGLMVSEPVNTRANTLAISEGVGAVGREATWDDF
PNGRWGDARSPAYGEIDGYGVSLHMSVTQAIRLWGTPKTVQDINNIFIRHIKGQLSAIPW
SEEELLPESNIIQQELLELNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVEL
FIPSSDWAGLVARLNEVTDNTICFYAANAAGDFVSSDSSGGLVLEGTEASTNAVTWGVFP
GKEIITPTIIEEVSFRAWAEEAFKIWGEWSKVYGKGSESEALLERVRSEYWLVNIIHHDY
VERDALWKLLSGEKEK
>A0A1H7SP02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptacidiphilus jiangxiensis|TrEMBL
MALGTPSTRPDRAVSIRDLLASGAKSYSFEFMPPRSPQAEAGLWTAIRRLESLAPTFVCV
TYGAGGSTRGRTINITGRIAAETTLTPVAHLTAVDHTVAELRNILGCYADQGVRNVLALR
GDPPGDPLGEWVAHPKGVNYASELVGLIKESGDFCVGVAAFPERHPRSTDWDEDIHHFVQ
KIRAGADYAITQMFFDVDLYLRFRDRVAAAGCEVPIIPEIMPVTSIRSLDRIPTLSTAWF
PPQLRDRMLAHADDPAAVRAIGIEYATDMCRRLLDEGTPGLHFMTMNFSTVTSEIYQNLG
LTPQG
>A0A328HKF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter globiformis|TrEMBL
MTNQLPVRLEIIPTDGIVAKVQTYVSAKSTLTVTCLPHHGVETTVRASVQLGRLGYKVIP
HLAARSIESRAQLARMLRDCEAAGITEVFAIGGDAPEAAGPYGSSGRLIEDIADLTGGTM
AIGVAGYPEGHPKCNELQMLDALLEKQHLASNVVTQMCFSAPRIGWYAELLRREGVDLPI
WAGVAGAVPRAKLIALATKIGVGPSLKFLNRKGPLARGLLNAGSYSSRSLVSELAAIDPA
PAGIHLYTFNNVETQPAMTWSDGADAKAS
>A0A0W8FQF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrocarbon metagenome|TrEMBL
MSPRYPLKSNGIKEENLRISMRENLFKEALLNPSVFPVTWELVPGRGAKESAQEKTLSLA
KQAAESGKICALTLTDNPGGTPAMSADFMGSEIVNLGIEPLVHFTCKDKNRNQIESQLYA
LDRAGVRNLLVMSGDYPVSGYRGRPAPVFDLDPIHTLQLISDMNKGLTYPGVKGNIRHQP
SIFFVGAVVSPFKATEAEQLLQYYKLKKKIDAGAQFIVTQLGYDARKFHEALLFMKQNNF
NLPIIGNIYILPYGAAKMMNRNELPGSVVTDKLLAEIDKERNDSDKGESARILRAARMYA
ILKGMGYSGVHIGGHNIKHEQVERIITQGEALASQWRDLIRYFDYPIPGGFYYFDNDSQT
GLNLDKPTNRQSRPLDATVGFTYGFSRFFHNLMFEPEKKLYSLMKKLSGKVTGTKIESIF
HKLEHWTKVVIFDCKDCGDCALIDVAYLCPMSQCPKNQRNGACGGSFEGWCEVYPGKKKC
VYVRAYARLKKHQEEAQLSKNIVEPCNWDFHQTSSWLNFYLGKDHTSKRHSGNSSGN
>A0A419A288|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus aestuarii|TrEMBL
MPAPKVSFEFFPPKTLEASFKLWETARALAPLDPDFVSVTYGAGGTTRQLTHEAVTTINR
QFGLQVAAHLTCVEATRAETMEIVQSYADAGIREIVALRGDAPKGADRFTPHAEGFANSV
ELIEAIAARGDMTIRCGAYPEPHPDSGDEAADVTWLKRKLDAGATSAITQFFFEPDTFFR
FRDRCAAAGIDAPVIPGILPVQSWAGTKRFAATCNTTVPDWAEDAFAAATLEGPEAVRAV
ATGLCVDLCESLIAGGVDQLHFYTLNRPELTRDVCAALGVRPKPGLEAVA
>A0A521G0Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electronema sp. GS|TrEMBL
MLKTALQRPHEFIITYELVPGQSSGGRRVERMLDFARHVKADGRVSALSVTDNPGGSPAL
APAAIGEELLNIGIEPLIHFSLKDKNRDQVVSHIYLYQRLGLHSLLVLGGDFPKPGYYGQ
ARPVFDLDSIQTLRLLRDMEQGRFLGGDAEVQPLFKGCVVSPFKATEAEQVWQYVQLRHK
VEAGADFIISQLGFDLHKFNELITFVRRSGITLPVLANVFIPSLPVARAMAAGKVPGVLL
AEELLTQIEHEAAAGQSQVRLERAAMMIARLKRSGFQGVHLGGNGLSFADLSTVLDKCIQ
FDQEAELPAATWNFPFRKTWYFYRQKASILEETQLRPGLKPGSVKMRALSHRLMFDQQQL
TGRLFAHFCLYCAQGKRRTAALTLIERAVKRVLFNCRMCGDCTLARATFLCPQAGCPKRL
VNGPCGGSRSGFCEVFPERRCFWVRVYERLAPQTTLALLVAQPPLPPKDWALEKTSFWIN
LFTGRVRKTK
>A0A451CWD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MIYIIKDSNKPYNYESYHLKNKIKVSFEVFPPQNSKLEKKLLNSICVLNQIRPDFFSVTN
SIHAKNRDKTFFVVQKIRALTKVNVFAHFTTIGLNQSEIKNIACKYWDCGIKHIIALRGD
LPDQYSRKIIYANDLIKLLLSIHDFEILVAAYPELHPESRNIQEDLINLKNKADLGVKKA
ITQFFFSVEKFLKFRDNCTNIGLPITIIPGILPILNINQLKRFSCLNNVYVPKWIFSAFD
EYKNDLKQCMDLSIRIAVNLIISLYKEGITNFHLYTLNQSTLSFKICHQLGLI
>A0A414S5S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea longicatena|TrEMBL
MKISDILVEKTPHLSFEVFPPKTDAAYEGVLKATEAIAELKPSYMSVTYGAGGGTSKNTV
KIASHIKDKYNVPSLAHLTCVSSTKEEVHQVIDQLKASGIENILALRGDIPQESEFPLLN
HYQYAYELIEDIKSQGDFCIGAACYPEGHVESEHKKDDIAHLKQKVDCGVDFLTTQMFFD
NNILYNFLYRAREKGVTVPVIPGIMPVTNANQVKRILSMSGTNLPERFKAIVDRFGDNPK
AMQQAGIAYATDQIIDLFANGINHVHVYSMNKPEVAAAIQANLSEILNK
>J0KJ02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. CF316|TrEMBL
MNAAKAQATGFPVSLEFFPPKTPAGADKLRAERQQLYVLSPEFCSVTYGAGGSTQEGTFG
TVREILAESVPAASHFSCIGATRASVREQLDQLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLKAYLAKVQAGADAAITQYFYNAD
AYFRFVDDVQALGASIPVVPGIMPITSSTQLLRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDRLRSAGVPALHFYTMNQSAATLEICRRLVL
>A0A8H2XJW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKVTEKIQQAEKDNRVWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSELVKTCQGVIGMETCMHLTCTNMHQEKIDVALREAKANGCRNILALRGDPPSGQEE
WTTVEGGFQHGIDLVKYIRREYGDYFDVAVAGFPQTIQLPEAEAKQEMQWLKEKCDAGAN
FIFTQMFYDADVFIRWVKAAREAGITIPIVPGINPIQTWNGFIRATSLSKTDIPQDLMDV
LEPHKNNDEKVRELGTKIVANLCRKILDADIGIKGLHFYTMNLEKGTKLLLEELNFVPRV
ETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTPEEGRKIWGTPTTIDDIKTLFAKFCSQQLKALPWSDQPPSTEMLVIDQQLT
HMNELGYLTINSQPAVNGARSDDKAFGWGPKNGYVYQKAYLEFFVHPDQLQTLMKRIERD
TNVTYYAINKQGDLKTNSTTDGPTAVTWGVFPGKEVIQPTIVEAVSFMAWKDEAFELGCQ
WAKIYEAGSPSRKLIEDMMDEYFLVNLVHNDFHDREAIFRPFFADASLKANGDAETPAVN
GVKQANGLVNGHSTVAHA
>A0A8H3HYR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKVTEKIQQAEKDGRVWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSELVKTCQGIIGIETCMHLTCTNMPQEKVDVALRVSALFTRVLIDPDVILNHQEAKA
NGCRNILALRGDPPSGQEEWTSVEGGFQHGIDLVRYIRREYGDYFDIAVAGFPQTIQLPE
TEAKQEMQWLKEKCDAGVNFIFTQMFYDADMFIRWVKAAREAGITIPIVPGINPIQTWNG
FIRATSLSGTDIPQDLMEILEPHKNNDEKVRELGIKIVADLCRKILDADIGIKGLHFYTM
NLEKGTKMLLEELNLVPRVEAIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWD
EYPNGRFGDSRSPAYGELDGYGIWIKQTPEEGRKIWGTPTTVDDIKTLFSKFCSQQIKAL
PWSDQPPSSEMLVIDQQLKRMNELGYLTINSQPAVNGARSDDKAFGWGPKNGYVYQKAYL
EFFVHPDQLHALIKRIERDSNVTYYAINKQGDLNSSSGYSVADSE
>A0A829AET2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli KTE119|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6P1JCK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. VKM Ac-2804|TrEMBL
MTRARFEIIPSDGIGEEAERAFPDPAAVTLTVTSLPKHGTERTIDAAVELAGRGFRVVPH
LAARNVDGRDALERALGRMRDAGIDEAFVVSGDAKSASGSYSTSLELIRDARELRPELAV
DIAGYPEGHPHLSDESIAKHLRERAPYLRGIVTQMCFDVDAVVRYADGLRDSGIDAELWA
GVPGPVERAKLLSLGARIGVGSSLNFLKRSSSVAGGLLRGRRFDPSAFVARLEAAAGDRL
AGLHVYTFNELTGLRDF
>A0A4P7QDK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium endometrii|TrEMBL
MAPRVSASFPLDAVEDGAPGFGGLQQPDLEGAHRTALSFEVIPPRHDADEAKVAALLETL
ESYRPDYIAVTSSRRSGWLEGTTKFIELISRTTSMRPLAHLACTAGTRQELADDINRLVD
AGVRGLLALRGDLPEGVRGLPETHLQHADELVRLIRGLEAGQAERFAAGSLAVGVACYPN
GHVESANFDEDLDVLLAKQRVGANFAITQLFFDAGDYLKFAAQARLAGVKIPLIPGIMPV
TSAARLKRMGQLSGLDVPESVVGRLEAARTPEEEKEIGMQLTAKLAQTVLAGGARSLHIY
THNSADVTRDLLDRIGIAPRV
>A0A3D4GKL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp|TrEMBL
MRIRDLIAARRPFVSLEFFPPKEREAWAGFFDVVERLLPVHPLFVSVTYGAGGSTHAHTL
EIVSRLKTAYGLEPMAHLTCVGASREKIRGFLDGLRAAGVDNVLALRGDPPRGQENFVPD
SDDFRHASDLVGFIRREYPGLCLGVAGYPECHPEAVSPEADLDFLRQKLALGGDFVVTQL
FFDNDCYFRFVEKVRALGIDAPIVPGVLPVMSLASVKRLVGMCGATLPPAYLAELEAADA
SGGAAAVAKAGIAYATRQAKDLLARGAPGVHLYTL
>A0A1I5PLE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus dictyosporus|TrEMBL
MTRSVRELLASSRPTWSFEFFPAKTPEGEAQLWTALRQLERLQPSFVSVTYGAGGSTREG
TVAVTERIAAETTMTPLAHLTAVDHSVAELRNVVSRLAAAGVRNLLALRGDPPGADPQAD
WVRHPEGLEYASELVELIRSMGDFSVGVAAFPERHPRSPDFDTDVEMFVRKCRAGADFAI
TQMFFRVEDYLRLRDRVAAHGCDVPVVAGVMPVTNARQITRIVQLSGQAFPEELAARFAE
LDGDAPEAKAAVRAYGVEVATAMCRRLLDEGVPGIHFITMNRSTATREVFTNLTGTGTSV
PSTLAAS
>A0A2X0P5H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbotryum silenes-dioicae|TrEMBL
MSRRITDKISSLGPDEPFYTFEVFPPKTSPGVSNLISRLSRMSSLNPSWIHVTWGAGGST
HSTSLQLAEAIVSKTNGLGLDACLHLTCTNMERSVLDEALKRAKELGVVNLLALRGDPPR
GEEYWVASDGEFQHATDLITYIKEHHENDFCIGVAGYPEGHADSADKSADIDYLYAKQQA
GAEFVVTQLFYCVETFLKWHKACRDKGKLATGVKALFGDLALTLLVSGITIPILPGIMPI
QNYQSFRRMTNLCKSHIPPQIVKDLELIQHDDQSVKDYGVRLAVSMMREIWHAGIRGYHL
CTLNLEKSVSRVLEQLDWVGHPLASPLIKESRANGVDASKSSSLLPSQVELLRGKGSKGG
VDGQGARKDSPTSWDEFPNGRFGDARSPAYGDLDGYGVGLKLTPAEALRQWGSPTTLADV
SNIFSSYLSDKQASIPWSEEALRAETKTITQHLIRLNDERHWWTVGSQPAVDGAPSGDPV
YGFGAKGGYVYQKAFVEFFLTEAELDQLERRAEEDAKARKEKDEGEGLIKWYAGNRAGKL
RSNMKKDNVNAVTWGVFNAQDIVTTTLIEEMSFKAWSEEAFAIWLEWSHLYPANSASRQF
IRELADTRWLVSVAHHDYKQIDGLWQWLLAAPKI
>A0A1P8M6Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. QXT-31|TrEMBL
MSPPSLIETHPNLSDTAPVALSYELFPPRSPAAAETLWTTIREIEATDPDYVSVTYGASG
SNRDTAVELVNRLVLETTLRPLAHLTCVGNTPTELAEIIGELLDAGVRGILALRGDLPKD
SDAPVNGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTQQYADLVTRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAPELIERMAAADSDAERLRIGVNATVDLANAALDAGAPGLHIYTFNEHQSALEVLDKLS
LARPARPSGRLNTLARRQLAS
>A0A659KEW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E2748|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A060NQP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serpentinimonas raichei|TrEMBL
MGRVYAMALPLSFEFFPPKTPEGALKLRAVRQQLYTRQPEFCSVTYGAGGSTQEGTFATV
AEILAEGVPAAAHFSCIGATRAGVRAQLGQLQGMGVRRLVALRGDMPSGYGLGGEFQYAS
DLVAFIRAEFGSAFVIEVAAYPEVHPQARSPQADLQALLVKVRAGADSAITQYFFNTDAY
FRFVDEAYALGIDIPIVPGIMPITNASQLLRFSDACGAEVPRWIRLRLLGFGDDTASIQA
FGREVVGDLCEQLQQAGVPGLHFYTMNQSAPTLALCERLGL
>A3V5L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yoonia vestfoldensis SKA53|TrEMBL
MSTPTVSFEFFPPKSLEGSFRLWDCVNTLAPLDPTFVSVTYGAGGTTRQLTHEAVSTIHR
TSGLNVAAHLTCVDATRAETLDIAQNYAAAGVREIVALRGDAPKGQATFTPHADGFASSV
ELIEALAETGQFTIRVGAYPEKHPEAVDQAADIAFLKRKIDAGATSAITQFFFEADTFFR
FRDACAKAGITAPIIPGILPIENWSGAQRFADQCGTHIPQVIRDAFTNATRDGTTDLLAT
ALATELCDDLVRGGVDHLHFYTLNRPELTRDVCHALGITPKARLQNVA
>B8E8J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella baltica (strain OS223)|TrEMBL
MAFHHAQHSQSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPGWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>I1DS16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter concisus UNSWCD|TrEMBL
MLKEKILNKEKGLVLYGLTPPKAEFEEAKLREISERWSGRINDIKADGLVLYEVQDESER
NDSERTFEFSGTLSPEIYYKKYLNVATPSIFYRVASGYGEDEFRAALKAQSSNLNVLVGA
TSSTQKVRLNLALAYEIASEFKELAVGGVCIAERHGKKGDEPQRMREKIAAGAKFFISQA
IFDAQLARKFLEDCAAAKISEPIFLTFSTAGNAKTLEFIKWLGVSVPSSVEERLNLSSDY
LASSCEIIKEIWCELKKFGDENGLNLSINIESVMAKRAEIEASLELTKSIRELV
>A0A2E8T327|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MATAIEQIQAAAANWSIEVTPTGATKIESFRDCLNEGTTVNVTFLPGTDPADTIAVCERL
HNDGMKPVPHLAARSLRNADQLDELLTAYTSRCGVEEVLCIGGGVDDPVGDFTATMEVLK
TGLIQKHGIRHIGVAGHPEGSPDISDDEIAEALGAKNELARAEGLDLYIETQFCXEADIV
LDWERRVRAAGNALPIRIGIPGPATIKTLFRFAQISGIGPSMRFVAKQAKNVAKLMTVQS
PHLLIAGLAEGMAADGDCLIRHFHFYPFGGFARTATYAGAXADGKIEMLPKGGFNVTEG
>A0A525C8W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp|TrEMBL
MRIVDLMATSGPFISLEFFPPKEKDKWPDFFAEVDKLKVLAPMFVSVTYGAGGSTRDFTL
EIVTRMKQELGLEPMAHLTCVGASKQSIGEYLTALQNASINNVLALRGDPPKGQETFVPD
SEDFQHASDLVEFMAKEFPAMGAGVACYPEKHQEATSLADDIRFLKDKLDKGAQFAVCQL
FFDNSHYFAFVDKCRDAGITQPIVPGILPVLGPNTLKRAVSLSGSSIPEGFIEALEAAEA
KGGVEAAKDVGIAHARAQIEDLLTKGAPGVHLYTLNKAEACLRIMDGIKLG
>A0A3A8R837|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus sp. AB032C|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTVEELAPLEPGFVSVTYGAGGSTRDRTV
DLVTHIKKHTGIEAMAHLTCVGHTRDELRDVLRRLDAAGIENVLLLRGDPPLGQATFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVGALKGRS
>R8GTB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VD196|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6V6YPK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium salmonis|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKHEQSFVPKDGGNHYAVDLVRQINDLNCGKYLHEVMDIDNRADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFNFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A378R576|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella caviae|TrEMBL
MNQQFLDQLAALETLAKSLKTDLGNHLAKGVQSAASQAAPSHKPKFSFEFFPAKTADAQE
KLTQTFDELNTLNPQYFSVTYGAGGSTRDTTLGIVKNLLARSDTPIAPHLSCIGDSKAEI
GELLNIYKAIGVTRLVALRGDLPSGQVNMGELPFAVDLVKFIREHSGDHFTVKVAAYPEM
HPQAKNFSQDIDNLVAKHHAGAAGAITQFFYNPESYLYLRDKVAARGVDLDKFELTAGIM
PITNASNLIRFADSAGADVPRYIRKQLAEYGDDSKSIRAFGFEVVLKLCEHLIREGVPSL
HFYTMNKVKPNKELVEALGLV
>A0A7V5C6I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MSELKSGSNLEKVLKAGHFAFTGECGPPQGANVEHLKEKYSHLKGMVDAVNVTDNQTAVV
RMSSWAASTLMVQDGLEPNFQMVCRDRNRLAMMGDILGVHAMGIRNMLCLSGDHQQFGNH
PESKNVYDIDSI
>A0A7W3PHC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Promicromonospora sukumoe|TrEMBL
MVAEVHPHRPTVSFELMPPRRPDAAPNFWETAQRLVAARPDFVSVTYGAAGGDRATAREV
LATLLRGTPVLPVAHLTCVGASREDVSAVIEEFLEAGVRSFLALRGDPPRDEPDWRPPAD
GVRSSVDLVRLLRQVEERRCAADVSTALRSAARPLAIAVATFPDGNPGAGTTREQEVRRL
LEKQEAGASFAITQFFYRADSYTGFVEAARAAGVTIPILAGVLPTTEARRLRRVEELTGV
AAPADLLRDLDRLTGPDGAVDAEAQHAHGIEYSAALAREVLDAGAPGVHVYTFNKHRPAL
DLLDRVGLTGRAAA
>A0A6D2CCH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter bilis|TrEMBL
MLDQLITKLHSNQAFLSVEVSPSLSSTIGQSVIDELKSLKQADCFVCTDSPLARLKPSSI
LTSIKLQNALKKPVICTFSMRDRNSIALCGDILGANEFGLRSFLSLSGDGVKNGDCVGAK
GVFEESSLKLGRIIDGLNQGIAANGKVLKDSVETIYNFSVINSYANNTESLKKKMLKKLS
NSAVQGLFTQPVFSLEAARFLLESMESINKELGQNCVMILGFFPVLSYKVALFLRDKLPG
VYIPNEWVQKLEKASIKGKEVERKIGLELSNKLFKDLQTLHNKFHFMSANKPSLLREFV
>B5D0D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola plebeius (strain DSM 17135 / JCM 12973 / M2)|TrEMBL
MKVIDLIKNSKEPVFSFEILPPLKGNSIQKVYHIIDKLREFDPKYINITSHHSEIVYLPQ
PDGNLKKTTVRKRPGTVAIAAAIQNKYGIQAVPHIICKGFTKEETEYALLDLNFLGINNL
LLLRGDSKPLDIAEKDLCLYHEHATDLQEQVNRFNQGIGLDGSKIEGIETPFSYGMACYP
EKHEEAPNMESDLFYLKEKVRNGADYVVTQMFFDNEKYYAFVERCRQEGIEVPIIPGIKP
VVFKNQLNVLPKVFRTDIPEAFASELRKCTTDEEVKAVGVEWCKAQCKDLLAHGVPGLHF
YTFMASDSVYKVAKEVY
>A0A5P9QGK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimicrobium xylanilyticum|TrEMBL
MSVSLATGRPTVSFELMPPRNPSAAPKFWGVAERLVAARPDFISVTYGAAGNDRHTAREV
VARLLRETPVLPIAHLTCVGAARHDVAEIIDDFLSDGVRSFLALRGDPPVNYPDWQPDPD
GLTSSDALVALLREVEAERCAAHPGNALRSAARPLTIAVATFPGGNPAAGTTPGQEVQRL
LEKQQAGADFAITQLFYEAETYVTFVDAARAAGVTIPILAGLLPMTEPRRLHRVEELTGV
PVPRHVLPALEAADDDASRHAIGIAHSVEVARAVLDAGAPGIHIYTFNKHEAALDLLEGV
HLGGGATDAPDLARGPRVSASTERNG
>A0A2Z6E015|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilus thermoluteolus|TrEMBL
MEYSVEFFPPQTPEGMAKLSATAQKLQNSGRFAYASVTYGAGGSTRDRTFAAVDALQAAG
WDVAPHLSGIGATEASIVTILDRYRAAGIRRLVLLRGDLPSGVVDPGPFRYARDLVAFVR
ARYGDTFWIAVAAYPEYHPQAKHATADLDAFAAKMAAGADCAITQFFYNPDAYAHFSDEA
ARRGVTQPIIPGIMPITQFFRLARFADSCGAEIPRWIRRKMEGFGDDVASIRAFGHEVVA
RLLERLRALGAPGFHFYTMNQAEPTLALL
>A0A375B8H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus taiwanensis|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLRPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVRAGADSAITQYFYNADAYFRFVD
DVRALGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A158JPQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia cordobensis|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRASRAELKKLSPKFVSVTFGAGGSTQQGTLDTVLEMAA
EGFEAAPHLSCIGSSRDNLRAILANYREHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQEHGDWFNIEVAAYPEFHPQSRSPRADLENFARKVKAGANSAITQYFFNADSYFKFVE
EARKLGVDVPIVPGIMPITNFSQLMRFSDMCGAEVPKWVARRLESFGDDRESIRAFGVDV
VTGLCRRLIDEGAPGLHFYTLNGAWASKMICERLGFKSV
>A0A0A3A433|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallibacterium anatis 4895|TrEMBL
MSYAKEIDVLNRSIADLNGDINVSFEFFPPKNEKMETLLWDSIQRLKSLQPKFVSVTYGA
NSGERERTHSVVKAIKQQTGIEAAPHLTGIDASPEQLKAIAKDYWDSGIRNIVALRGDEP
PGYDKKPFYAKDLVKLLKEVADFDISVAAYPEVHPEAKSAQADLIFLKQKVEAGASRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFVQLQKMAKVTNVKIPSWMFKLYDGL
EKDQTTRNLIGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGVRPSLAA
>A0A0R3LZ82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium jicamae|TrEMBL
MTEVTPPAFDGHRALHSPRISFEFFPPKTEEMERSLWDTINRLAPLTPNFVSVTYGAGGS
TRERTHSTIARILKETRLVPAAHLTCVGAPKGEIDDVVARYHEIGVRHIVALRGDPTTGI
GTAYHAHPDGYQSSPDLIEGIKKRYPDIEISVSAYPEKHPESPTIDADIDTLKAKVDAGA
ARAITQVFFDNDLYFRYLDRVRARGIDIPVVPGIMPMHNFKQARSFVTRAGTTVPNWLAD
KFEGLDDDADTRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A1B1TKS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. PCC 7003|TrEMBL
MTTRLRRAIENRDFVVTAEVAPPKGGDPTKMLRMAKLLGDRVHGVNVTDGSRAVMRMSSI
AASTVLLQNGIEPIFQVACRDRNVIGLQADLMGAHALGLRNVLALTGDPVKAGDHPKAKA
VFDLESVRLLKLISKLNNGQDFNDKKMPDGPLDLFPGAAVDPQLKSWYTIESRFARKVES
GAQFFQSQMITDFQRLEEFMHRVASQYDVPVFAGIFLLKSAKNAQFINRCVPGAQIPDAI
IERLAQAENPLEEGLKIAAEQVKIAKNLCHGVHMMAVKKEDLIPQILDLADVSISVPTAP
ALV
>A0A653WA96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 9Ag|TrEMBL
MSHTRSHSFSFEFFPTKTDAGHEKLLATARCLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVSTAPHLSCVGGSKQELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMESIQT
FGAQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWDNLKLSR
>A0A0Q5MEL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. Leaf168|TrEMBL
MASSASLNLADARALLLSPLGPVARAGSNREAVRVSFEFFPPKTDEAEANLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIITETSLRPAAHLTCVEASREEVDEVIEGYKAIG
VDHIVALRGDPPGGAGIGGVYQPRADGYANATELTAAINRIGGFDVTVGAYPERHPESPS
IDNDIEVLKAKVDVGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLQ
RMCDACGASIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETAAAQ
>A0A6G8DH30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbulbifer sp. SH-1|TrEMBL
MSDLRISFEFFPPKTEEGREKLYKTREELQAFNPAFFSVTYGAGGTTRDTTANIVCNLRR
DGVSIAPHLSFGGDNEETVLGLLKRYKESGVDRIVALRGDMPSGMGSVAQLVYANELVAF
IRRHTGDHFHLEVAAYPEIHPEAESYDADLRFLKGKFEAGANSALTQYFYNPDAYFYFLD
QCEKAGIDAPIYPGIMPITNFANLARFSRNCGAEIPRWLKYRMESYRDPEDVKKLGLEIV
TDLCETLLEGGAPGLHFYTMNQVAPSADILRALNFADRAI
>A0A838GES8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporichthyaceae bacterium|TrEMBL
MADLAPSIGDLLRRGEPAFSFEFMPPRSEAGEVALWRAIRELEALRPTFVSVTYGAGGAT
RDRTVRTTARIASDTTLTPVGHLTAVSHSVSELRHVIGQYADAGVRTVLALRGDPPGDPA
GDWVRHPHGLGYAAELVALVRASGSFSVGVAAFPEKHPRSPDRATDVAHLVSKVRAGADF
AVTQMFFRVEDYLRLRDDVVAAGCDVPIIPGLMPVTNLAQIERFAVLSGASLPADLAARL
AAVADDPQAVRSVGAAHAADMAQRLLAEGAPGLHFYTLNNSTATREIYAELGLDRSRHLA
G
>Q8A146|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)|TrEMBL
MRVIDLIHNSEKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLFWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEALKCKNDKEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A840QC77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora phatthalungensis|TrEMBL
MTAVVDRLNTEKTSFSVEFFPPRGNDEERILWRAVRELEPLDPAFVSVTYGAGGSSRDRT
IRTTGRIAQETTLTPMAHLTAVDHSVAELRNVIGWYAASGVHNVLAVRGDPPGDPNGEWL
RHPEGLTYAEELVRLVRELGDFCVGVAAFPHGHPRSADLDIDVDYLVRKIHAGAGFAIAQ
LFLEPEYFLRLRDRMAARGCGVPLLPGVMPIITPRVLGKFSELAGVPVPSEVSEQLLPLT
DDPAGFRSAGVDLVTRLCERLIAEGVPALHFYTLNRSKATRQVVADLGL
>A0A7J6ZN50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Abscondita terminalis|TrEMBL
MGLLFAKLWSLFGNEEHKIVIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEVVWRNI
HFIMWDLGGQQSLRAAWSTYYTNTEFVIVVIDSTDKERLITIREELHKMLSHEELSKAGV
LIYANKQDIKGSMTATEISRQLDLTSIKKQQWHIQSCCALTGEGNVFKKAKELKAKTLSV
EVISTTCNEEELDEVPKSFCSAIWAYKGDILEDVKNTEPFVSLKKLSLRNQNLLFHLPGR
NLNQNDVNEILKVLKELNVRNLLVLQGEVVAERERRDFKYAIDLVKYIRLHYGAYFNIGV
AGYPNVHPEAPNANVDILRLKEKVLTGSDFVLTQMFFDYNIFDNFYKKFKITCPDTPLLV
GVYIITSYESFSLLERLYKKELPEDVVDFVMKNKDKEEIIAEYGIQLCVNLIKKVLSIND
SQIAGIHFFSWNKFNYVKRVCDILGFYEVHKEISNRMVPCSFFHRRENES
>A0A8I2KER7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae|TrEMBL
MALKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSHLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRSAAKSAGAAA
>S8F566|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fomitopsis pinicola (strain FP-58527)|TrEMBL
MKLIEKIAKYDKDRPWFSFEFFPPKTDQGFENLLSRIARLVTFDPLALSVTWGAGGNTKE
RSLELAGITQSEHGVDTVLHLTCTNMKKGMIEDALRDAKARGIETILALRGDSPRGQEHW
IPTDLRFAHAVDLVKFIKTTPEFASDFCVGVTAYPDGHPDKETDEEGELEFLKQKIDAGG
DFIITQLFYDVDSFLAWVGKVRQKGITVPIIPGIMPIQTYASFLRMTKLCGTRVPPELMA
DLVPISHDDQKVKDYGVDLAIKMVRQMTASGDIRGLHFCTLNLEKSVVRILENIGGAGAS
LRSANRLITDAPSSADERAITPHSAADSAAVSLAVSGPQPEGEAGKGELNNAASWDDFPN
GRFGDFKSPAYGATDLWGSSTLSRNQALEQWGHPRTLDDLTTMFLRHLHSKIATTPFSPA
PLSPESLMIIEHLETLTRHGWWTVGSQPAINGASSADEIVGWGPRGGYVYQKCFVECFVE
EKDLERIERKVREKGEGWIDYYAANVKGDLHTSASHEARNAVTWGIFPGQEVAQTTIIEE
ESFLAWKDEAFGIWEEWATFYPPDSEERQLLEGIRNGRWLLTLIHHEYTNPSALWSFLFE
DDPVV
>R0NSU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis 13/39|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKGKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQA
>B9Z228|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogulbenkiania ferrooxidans 2002|TrEMBL
MSTKPRTFSFEFFPPKTAESIAKLRTTRQQLAQFKPEFFSVTFGAGGTTREGTLGTVLEI
RNEGYAAAPHLSCIGSTRDNIRAILNEYRSHGIRHIVALRGDLPSGMGEAGEFRYANELV
AFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLNNFVRKVQAGANSAMTQYFFNADAYFRF
VDEVQARGVDIPIVPGIMPIANFGQLCRFSDMCGAEVPRWLRLRMQAYYDDTASIRALGL
DVVTELCDRLLTGGAPGLHFYTLNQAGIVSTIWQRLGL
>A0A0U4CNE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sedentarius|TrEMBL
MKVTDHLAQANGKTLFSFEVLPPKKGENIHTLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFTKEETENALIDLHFLGIDS
ILALRGDPIKSEGVFKPEPDGHAYACDLIGQVANLNKGEYLDQEQDDVWATDFCIGTAGY
PEKHFEAPNYNADIRYLRHKVDRGADYIVTQMFFDNEEFFRFEKLCRAAGIDVPIIPGLK
PLTTKSQLSMLPRAFYLNLPEPLVEAVSQCRDNDAVRTVGIEWCLNQSRELMAHGVPCLH
YYSMGKSESIRRVAKELF
>A0A0G2H5X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeomoniella chlamydospora|TrEMBL
MSREQADRWARVDNMHIKDKLADARAKGKPSFSFEFFPPKTAQGVQNLYDRMDRMHDLGP
AFIDITWGAGGRHSQLTSEMVSVAQSQYGLETCMHLTCTDMKKEKVDEALQRAYKAGCTN
ILALRGDPPRESEKWEATEGGFRYAKDLVKHIKENYGDHFDIGVAGYPEGCDDQDDQNLL
MQHLKEKVDAGGTFIITQMFYDVDIFLAWVKRCREAGITVPIIPGIMPIQTHASFERRAN
WTKCRVPEQWKAALEPVKNDDAAVRDIGKGLVAEMCRKILEAGLNHLHFYTMNLAQATRM
VLEELCLTPSTGSPIPKPLPWRQSLGFGRREEDVRPIFWRNRNSSYIQRTQDWDEFPNGR
WGDSRSPAFGELDAYGIGLKGTNEQNIKLWGQPKSLRDVANLFVNYVHGKLDRLPWSESP
ISAEANTLKEDLISLNSRGLFTINSQPALNGVKSSHPVYGWGPPSGYVYQKPYIELFVSP
TLIATVLERIRGNEDLTFYAVNKTGKLETNTRDEGPNAVTWGIFPNSEIVQPTIVETVSF
LAWKDEAYRLGEDWSKCYVAGSASRKLIEAIAESWWLVNIVNNDFHQDKAIFEVFKDLQV
ATLDEEISGSVSTTGGHENLVNGFEKQKEAAANTSITTNGTNLSNELKN
>A0A2E5EBK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHIRDILARDKTTISFEFFPPKSDSACKALSDRLEAFELLSPSFVSVTYGAGGSTRQRTH
DLVVSLKSREQLDPVPHLTCVMQTATELDDILDRYARNGISNLLIIRGDKPADCEVYDSS
KEDFAHAADLVRHVKKFNENGHPMDTRGFGIGVAGFPEGHPETPNRLRQMEHLKAKVDAG
ADWITTQMFFDNRVFFDWCEQCELNGVSIPKIAGIMPITSIANMKRMADLAAGTNFPAKL
QRRLHKHQDDPEAVEQIGVHWASEQCNDLIDHDVRGIHFYTLNRSDATLRIFKALGAHSS
ELLRSTGV
>A0A5N0DRH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia colli|TrEMBL
MHSIPGRDRSNHGLPARITPAVSGVPSVVESLRIHSGPRVPFSVEFNPPRDAAGEARLWR
TVRQFERMHPAFVSMTYGAGGSTKDRTARITGQLAQQTTLLPVAHLTAVGHSIAELRALV
GSYADCGIRNMLVLRGDPPGDPLGEWQRHPDGVEYAEQLVRIVRDLGDFNVGVASFPQGH
HHSPDLDTDAAFLAAKLRAGADYSITQMFFEVDHYLRLRDRVAATDAEQGAKPIIPELMP
ITSLRTIARAEELSGRALPASIMRRLRAAAGTGPEENRAAVRAAGIEIATEMAQQLIDEG
APCLHFITLNFAKATNEVLTNLGYEVTAAPLSA
>A0A2G5W2S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. P10|TrEMBL
MSLLDKLQTNVLTADGAMGTILYSYGIDYCYEELNVEKPEIIEQIHQDYIAAGADIIQTN
TYSANANKLARYGLESHVTEFNKAAIQIAKRAAAPGGQFVLGTIGGLRGIRKSDATLDEI
EKVVLEQASALLAGDPDGLLLETYYDFEELSSVVTTLKKITDVPLIAQVSMHDPGVLQNG
LSLNDALHQLESLGADIVGVNCRLGPYHTIQAFDNVTLPEQAFLSAYPNASLLDVEDGRI
VYESEAEYFGRAAVLLRDQGVRLIGGCCGTTPKHIKAAKTQLTRLAPITEKVVHPEKPIV
IHEAGPTKHQPLHEKAKTERTVIVELDTPRHLETEDYIKGANVLYDAGVDAITMADNSLA
SPRISNMAMGSIVKMKHNIRPLVHLTCRDHNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELLQLIKKLNEGISFSGKPLRKKANFSISAAFNPNVRVIDRAVQR
LEKKIEAGADYFITQPVYTKEKIIDVYEATKHLDTPIFIGIMPLTNIRNAEFLHHEVPGI
KLSEDVLERMRECGDDREKSTETGLEIAKELIDTAAQYFNGLYIITPFLRYDMTLELYEY
IKEIDQKKKERELTHAETSY
>A0A8C7NXX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
MVNLVQRVEDTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRHRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIR
NYGIEQAVSMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVN
RRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKVRSKVISLTYW
APSRNITLYALVTTPEHPPPSGMC
>A0A7K4TJH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burhinus bistriatus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSKTFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6M1QEX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter silviterrae|TrEMBL
MSPPRPLQPTPLSGGAAPTALSYELFPPRNETASASLWATIRELETTNPDYVSVTYGASG
SNRDTAVELLHRLLSETTLRPLAHLTCVGNTAEELAGIISELLDHGVRGILALRGDLPKD
ASGAPKRGSLTYAQDLIELVRRVEQRRSALLCAGRVAIGVAAYPAKHPESPSIEHDVEVL
LAKQRSGADFAITQVFFHADQYKSLVARARRAGVSIPIIPGVMPLTSLRRVQRLGELTGV
EPAPALLDALGRADDSAASRRIGVAATVDLARAALDAGAPGIHLYTFNEHAAALEVLDKL
QLLRPGRPAVARRTPSPQLVQA
>A0A6N7W508|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scrofimicrobium canadense|TrEMBL
MSTPTISFELMPPRTSCDDPSFWETVDNLVAVHPDFVSVTYGAGGHNRDTAHAVTARLVR
QAPIRPLAHLTCVGASRTETTEVIDSYLASGVRSFLALRGDQPQGRAASPDALKSSIELI
ALLRSREALRCAESASAALRSAVAPLIVSVATFPAGNPAAGTTPTQEVERLLVKQAAGAS
FAITQLFYDADIYLNFVDEARQAGVTIPILAGILPATHPRRLRRVAELTGVAPDPLFMDA
LENAADPASLGIAESGRVIERILAAGAPGVHLYTFNQAKPTLQVLAAANLIKPETI
>A0A5B8CPZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilus medardicus|TrEMBL
MNHKTSYSFEFFPPKTAEGMANLRQVRQELAAFSPEFFSVTFGAGGSTRDRTMDTVFEIQ
AEGHGAAPHISCISSSKEEIRALLQAYQAKGIRRLVTLRGDIPSGEVSAGDFKYANELVS
FIRAETGDWFHLEVAAYPEFHPEAGSAQKDLDNFKRKIDAGADSAITQYFYNVDAYFRFL
DAAQKLGVTAPIIPGIMPIYNYTQLARFSNVCGAEIPRWLRMRLEAYGDDLASLRGFGAD
VVTEICAKLIAAGVDKMHFYTLNQAGIIGQIIRQL
>A0A102D914|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. FSW06-99|TrEMBL
MAIPQIHPNWDRAPTTITEGYSLEMTAKDKASLHEAAPLIPPETPIAVTFLPGEEASARI
AATVAVRELGLEPMPHFSARRITSEDDFEGYLHAVVREAGVRRCFIVAGDPPEPQGPYFD
TMALLATGAFERAGITAIGVGGHPEGHPNMSVEQCWDVLTRKAADIAARGMAPLVVTQFG
FDPDAFLAWLVELRARGIDAPVRIGVPGPAGIKRLLSFAARCGVGASTSVLKKYGISVTN
LLGSAGPDKLVDAFAAGLGPQHGRVRLHFYPFGGLRKTVEWIADYERRHTTP
>A0A4R1V9T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. PhB179|TrEMBL
MTRARFEIIPSDGIGEKAERAFPDPAAVTLTVTSLPKHGTERTIDSAVELAGRGFRVVPH
LAARNVEGREALERAVGRMRDAGIDEAFVISGDARSAAGGYSTSLELIRDARELRPELAV
DVAGYPEGHPHLSDESIAKHLRERAPYLRGIVTQMCFDVDAVVRYADRLRADGIDAELWV
GVPGPVERARLLSLGARIGVGSSLGFLKRSSSVAGGLLRGRRFDPSAFVGRLEAAVGDRL
AGLHVYTFNELDGLRAF
>A0A319BQB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus vadensis (strain CBS 113365 / IMI 142717 / IBT 24658)|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSNWTKTTIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTSLID
LNKKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQDVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A1Y3ZYL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor sp. An4|TrEMBL
MKIIDILNQDRPTLSFEVFPPKTSDTYDSVAKATQDIAALRPDFMSVTYGAGGGTSDYTV
GIAAGIQQQYGVDVLAHLTCASSTRDHVAQVLEHLKEKGIQNVLALRGDIPEGGAPAHDY
QYAAQLVRDIKAHGDFCIGGACYPEGHPESPTKNADIDHLKAKVEAGCQFLTTQMFFDNN
ILYNFLYRIREKGITVPVVAGIMPVTNGKQIARICKLSGTYLPERFKAIVDRFGDNPAAM
RQAGVAYAAEQIIDLIANGVEHIHIYSMNKPEIAASIQASLSEVLK
>A0A4Q1C2V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquirufa rosea|TrEMBL
MTKITEYFKSSGGKTLFSIEIIPPVKGQHLGELMGHIEPLMEFNPPFIEVTYHREEYVEK
EINGEIKRIPIRKRPGTLGICAALMQKFKVEAVPHVICGGFTKEETEDFLIDLHYLGIEN
VLALRGDQEKGEDRFIPKLGGHAYANELVEQIARMNNGQLLYEETESFPTNFCVGVAAYP
EKHFEAVSLDVDIHFLKQKVDAGADYVVTQMFFDNQKYFDFVDACRSAGIQVPIIPGIKP
LATAKQLEVLPSIFHLDIPKELSSAVLSASSSTAIRQVGIEWAIQQGKELIKAGVPALHF
YTMSKSDSVRAIASALF
>A0A1H2R0P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter pontiacus|TrEMBL
MTSPAVSFEVFPPKSVDASFRLWDTAQALAPLAPRFFSVTYGAGGSTRDLTHDSAHVLRR
TSGLPVAAHLTCVGASKAETLEVADSFAEIGVTDIVALRGDPENGAPTFTPHADGFADSV
ELIEALAKTGKFTLRVGAYPEPHPESHDQAQNVEWLKRKFDAGADEAITQFFFETETFLR
FRDACAAAGITKTITPGIMPVTNWKSARNFATRCGASVPAALDEAYAAAIRDDRHDLLST
ALCTEMCSELVSEGVENLHFYTLNRPELTRAVCRALGVTAQTSLSDVA
>A0A356VZT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
QIRRILALTGTALPQRFRYILDRFGDNPAAMKQAGIAYATGQIVDLFANGVPAVHVYSMN
NPSVAGKIRQNLSEILK
>R5ESA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:20|TrEMBL
MKVADLIKNSGSTGFSFEILPPLKGSSIEKSFKAIDTLREFAPLYINITTHRSELVYKDT
PDGLFRRVSERSRPGTVAVAAAIKNKYQIPTVPHLICSGFTALETEYALIDLNFLGICDL
LILRGDKAKHENRFIAASGGYEHAIELEQQVNRFNEGYFIDGTRMDLVSTRQFSYGVAGY
PEKHDESPNPDEDMKWLKAKVDAGADYIVTQMFFDNEKFFSFVDRCRAAGITVPIVPGLK
PISKASQLTLLPRVFHVDIPDMLVREIVKCKDDSQVKQVGIDWCTAQSLELKAKGVPSIH
YYSLMAVDSVYQVAKLVY
>A0A0B8ZFQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium subterraneum|TrEMBL
MNASYDQPTYDKLREARTALDTPLFAGLPGDINVSFEFFPPKTDALMAQLWDVVETLGPL
QPKFVSVTYGAGGSTRDRTHGTVARIIREARLPAAAHLTCVDASKAEIREVAESYWEAGV
RHIVALRGDMGAPGVPFTPHSDGYANAAELVAGLKQIAPFEISVAAYPESHPDSPSSQAD
IDNLKRKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAA
ACGAAIPAWMDGLFEGLDTHPASRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYA
ICHLLGLRPKAPALEKAA
>A0A4U7NF48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira catarrhinii|TrEMBL
MNVENFINKLENENEFTFTLEVTPQAKADLGYLAQKIESSKIEKYIDAFVIPDSPFANLK
ISPILASLQLTQRLKTEKPFIITQTMRDKNSIAFQNDFIGANYFDIRMVLALTGDPIVNG
NQKQAKGVFEGNSELLIKIIRNLNEGKSAGDFIFKEPLKKIYPFCSINSYSKNDDMLKVR
LSKKVASGVKAIFTQPIYEIETLKKFLNWIDEMPLKEMGLKEKPILMPGFFPVLSYKTAY
FIYYKLPGAYIPEDWLDKLKSASEKSEEEKKVALELSTNLFERMINIHKKAHIMSMNNYD
FVAKLLKDYNL
>A8A9S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)|TrEMBL
MRVICPKKMLNGPCGGVRGELCEVDDFKCPFVEAFRNLRSSEYLKPLLDPGFKVGCEVVE
VEPSPYVKKLEDFAVSAEVEPWGPEELERASKWRVDALNVTDNPLGLPHLDSVWASAALA
SKGKEVIAQLTCRGRTREALASSLLALDASGVNNVLALTGDWAPNAAFDLDAVRLVCLVQ
ALRKGVDWEGRKTRRVRLSVGVASNPYFSYEEKRLLRKAHAGAQFAQTQPVFKKELLYKI
KKYPLPTVPSLLLTTSRKVVRALMERGVDAKEFYEELVKAKREGKADELVLKKSLEMYEE
AYSSELPGVHLMAPGRPDLLERFLELLRL
>A0A1L3MXS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus weihaiensis|TrEMBL
MGTMLYAHGVDRCFEELNLSKPDDVKHVHQAYIQAGANLIQTNTYGANDIKLSRYSLEDD
IRKINKRAVEIARSAAQDSTYVFGTIGGIRSFKKSAHSIDELKRNFREQLFLLLGEDVDG
ILLETYYDFEEIKTVLQIARKETTKPIIANVSLHEAGVLQDGTPLTDGLLVLEDLGANVV
GLNCRLGPYHMLQSLEEVPILEEAYLSVFPNSSLPALNEGRLVYESDESYFKESAIKFRD
QGVRLIGGCCGTTPTHIKAMAEAVANLAPITTKEVRVPKSETVTVQDTGDDNAPPLQEIV
RERRSIIVELDPPKKLGMTRFLEGAQALHDAGIDALTLADNSLASPRVSNLAAGILTKEK
TGARTLIHLTCRDRNLIGLQSHLMGLHSLGIHDVLAITGDPSKIGDFPGATSVYDVSSFD
LISLIKQFNNGVSYSGKPLGAKTNFSVAGAFNPNVRHLDKAVLRLEKKIAHGADYFISQP
LYSNQQILDVYNETRNLNAPIYIGIMPLTSSRNAEFIHNEIPGIKLSDAIRETMAAAGTD
KAQARIEGLAIAKDLIDTAFDLFNGIYLITPFLQYDLTVELTHYIHEKEKQRAERKISHV
>A0A1A9S879|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eikenella sp. NML070372|TrEMBL
MFGTEISRWLRLKLQSYADDTASIKALGLDVVTEMCGRLLRHGAPGLHFHTLNQAGLSST
ICQRLGY
>A0A1M4YLU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium fallax|TrEMBL
MTKRNWFFSLEVFPPKVDSPLRTIYKALNELKEINPDFISVTYGAGGSLVNNKTAEISSL
LKNVYKIESLAHLTCISSKKEDIDKITEKLSSEGIKNILALRGDDNGIQRNDFNYASDLN
EYIKNKDKFNIISACYPEGHIENRDLDLEIENMKRKINNGTTSFISQLFFDNDIYYKFLD
KARSSGINVPIQARIMPVINKKQIERITTLCGATIPPKLSKILNRYEHNKEALRDAGIAY
AVDQIIDLISTGVDGIHLYTMNNPYVANKINDSIKLVLKAINNEYKNY
>A0A133ZAS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. DNF00584|TrEMBL
MVPRFSASAPLDLLEQRPTRTAQRVALSFEVIPPRHDADDAKVAGLIDTLARFDPDYVAV
TSSRRSGWLEGTAAFIERISHATDMRPLAHLACTAGPTHELEGWIDRLVDSGVRGLLALR
GDLPEGETALPPDHLPHADALVRLIRQRETEQFARFAAGRLAVGVACYPGGHAESASPDE
DLDVLLTKQRLGADFAITQLFFDAEDFLRFQQRARLAGVHIPLIPGIMPMTSLARVHRMS
ELSGVPVPDRLERRLRGDPTAGLELTVQLAGELLRGGAPGLHMYTHNDAELTTTILSEIG
IHP
>A0A364Y5S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseolinea flava|TrEMBL
MKVCDHLASANGRTLFTIEILPPLKGENIKNLFKNIDPLMEFKPPFIDVTYHREEYVYKK
KEGGLLEKSATRKRPGTVGICAALQNHYKVDTVPHIICGGFSREETENALIDLHFLGIDN
VLVLQGDGIKGEGRFVPEPDGHKFASDLLQQVVNMNNGKFLDEDISNTAPTNFCIGVAGY
PEKHFAAPNLKTDLKYLKLKVDLGAQYIVTQMFFDNAKYFDFVLKCKEAGINVPIIPGIK
PITTKTQSSVLPTTFHIDLPEELADEVEKCKDNAAVKEVGIEWAIKQSKELIKAGVPTLH
FYSMGKSDPIYRIAKALF
>A0A1A7NZ17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallibacterium salpingitidis|TrEMBL
MSYAKEIDVLNRSIADLNGDINVSFEFFPPKNEKMENILWESIQRLKVLQPKFVSVTYGA
NSGERERTHGVVKAIKQQTGIEAAPHLTGIDATPEQLKQIAKEYWDSGIRRIVALRGDEP
PGYDKKPFYARDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLIFLKQKVEAGANRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFIQLQKMAKITNVKIPSWMYKLYDGL
EQDQTTRNLIGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGLRPHLAAA
>A0A077R7V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melanopsichium pennsylvanicum 4|TrEMBL
MSNGTDTPIPPKGDTFWKITNKIAKAEKEGRTWWSFEYFPPRTAQGLTNLYDRIERMADL
GPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGC
RNILALRGDPPAGQSEWEPHAAGFTRAKELVEYIREQYGDYFAIAVAGFPEGHPEAVDGS
QKELERLKEKIDAGADFIFTQMFYDFDIFAKWVKDVRAAGITCPIIPGVMPIQTYGGFQR
ATARFGTLVPQYFHDALDPVKDDDQKVREVGTRLVGEMCKKIVGTGLGISGLHIYTMNLE
KGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRREEKIRPIFWANRAKSYVNRTETWDEFP
NGRWGDARSPAYGDVDAYGVKLRYSNDEAKQMWGNPTSLDDVKALFQKFCAGQVKALPWS
ETPVARETSVISEKLARMNELGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEFF
VSPEDLDALIARIEADPQITYHAVNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVES
ISFLAWKDEAYEIGRNWAKVYEVSSPSRTFLEEMFSRYFLVNVVHNDFKAADAIFEPFLS
PSKTSAVNGSLFGLSSTVADATGRIANSISSLANGIAKGHASTPAPSA
>S6GD99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Osedax symbiont Rs2|TrEMBL
MVIHDEPTPGEMLPILPGHSSAGRLERVLRAGHFAVTAELAPPDSANPQDVYARAELFDG
YVDAANATDGSGANCHMSSVGICALLTRIGYAPIMQVSCRDKNRIAIQGDVLGAAAMGVS
NILCLTGDGVQAGDHPQAKPVFDLDCMSLLETVRGMRDKAEFLSGRKISDPPKVFLGGAS
NPFAPPLDFRPHRLAKKIAAGAQFIQTNYCFDVPRFKEFMARSRDLGLLEKVFILPGVGP
MASARTANWIRNNVPGIYIPDAVIERLAGAKDQKKEGQQLCVELIQELSEIEGVSGIHVM
AYRQEESVPEIIKSSGVLQGRVPWYPGRDQKMLQERARS
>A0A067BX79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprolegnia parasitica (strain CBS 223.65)|TrEMBL
MKIIDKIRAKLEKDETFYSFEYFPPKTQAGVTNLYSRIDCMAQMDPLFCDMTWGAGGSTD
KLTLEISANVQKFSGLEMLMHLTCTNMSRGSIKNALDAAKDAGIQNILALRGDPPRGKTT
FEECDGGFSYALDLVKYIRQEFGDYFCIAVAGYPEGHPDSTDLEQDLRHLKEKVDAGADF
VVSQLFYDAKIFLGFVDRCRAIGISCPILPGIMPIQSYLGFTRMSAMCCKTIPAAIHEAL
APIKDNDEAVKDYGVTLGIQMCKELLEAGVAGLHMYTLNLERSTRLILEGLDLISSARRE
LPWRPSTMIKRVSESVRPIFWANRPKSYLDRTSSWDEFPNGRWGAESHYMHATHSIADRK
AMWGDAPTSLDDIYETFTRYCMGALKSLPWCDTPLHLETKSIQELLAGLNRAGFLTINSQ
PRVNAAPSDDPMFGWGGPGGRVYQKAYVECFVSPANLKHIIEKVSKLKWVQYHAVDVHGN
SYSNVGKGTTAVTWGSFPNKEILQPTIVDTDSFMAWKDEAFSLWLSLWGSLYETNSASYA
LLKEVHDTFFLVSIVDNNFVNGNIWDVFELSTTDAATTP
>B2TP86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum (strain Eklund 17B / Type B)|TrEMBL
MNIKNLFRDKKVVFSFEIFPPKTTSSIQTIYNTLDDLKGLNPDYISVTYGAGGSVKNNKT
IELTSLIKNKYGIEAVSHLTCISSTKSDIEYYLREFEKNNIENILALRGDIPIGSKITGE
LNHANELIKHISDNGQFNIAAACYPEGHIEHKGLYREIESMKRKEEAGASYFISQLFFDN
NLYYNFQDEVRAANINLPIEAGIMPVTNKRQIERILSLSGASLPDKFKRIMERYEHNPEA
LRDAGIAYAVEQIVDLISTGVDGIHLYVMNNPYVAKRISQSIENILLTVNKNQFV
>A0A511D033|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia asaccharolytica DSM 44247 = NBRC 16224|TrEMBL
MVAAIAPEVPGRLADALRTGRFAVTAEIGPPRGADLGPVRRAAEVLYGWVDAVNVTDNQG
ATVRVSSLAGSLALLDAGVEPVMQMTCRDRNRIALQSDLLAAGALGIPNLVLMGGDRPEH
GDHAAAKAVFDLDSAALMSAARGLRDDGTLLSGRAVDPPPRFLLGAVDNPGPDVERLAKK
IDAGAEFAQTQFVFDLDAFRGWLDRVRDRGLDARCGILAGVGPVRSLRALEFLAGLPGVV
VPPALERRLRGVPSGRVGAEGVRVCVETVQVLREMPGVAGVHVMVVGDEGGIPEILDAAG
FRRG
>A0A0J1GWF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium aquae|TrEMBL
MQPYMQCPAHLSQESELRVRYNDATRGVYFIGTTPPKTSTALADVAGIADKLVERIQDLA
FDGLIVYDIQDEGSRTSKPRPFPFKTTHDPRYYSSLLNQKTGRPVITYKSVVQSDVGEFD
HWLCEAWEQYNVRDIVLVGSPSTQNQISLPLNQAYQALLDNTHPFFTGGIMIAERHAKKG
NEHERLIDKYQKGCNFFISQAIYDTQATIDILTRYALECQSQGIKPQRIILTFSPCGSAK
TLEFIEWLGVSVPEATSLRILNAENPLHESIRMCCASLNQILEAVIEYDLPLGLNIESLT
NRREEIEGSILLYKLLRSTMDMYLAQHEFRKLQGVDKVF
>A0A1Y3D163|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4169|TrEMBL
MPQLSSFFQQNQFCILVEYLTSLNEIFPVKTAFAGYPAVMTLADRVHSDHDMAPLEASKR
YPDSVEKVLHFAGKGRDIQDFELFLQQAKAANINNLLLLTGDKLKEHHDGKDGTERSRYL
ESVNAVMAAKQSGGFCIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIDAL
KQAKAFLKRHHYPQKILACVMPLSLARANFMVKNKVAGIVITPHMLKVLADEKQAGLSER
VYLRCALQILMCKQLGFSGVDLSACHKPEEQMLLESYIEQYRHLGLDALESLWMSLWQIK
TGKEFIPELSSFSRQPSSSQMIKYYQLHLMHDALFDSKIAKGVGRFIFKSPFWERKAAAK
TLLKTEFISKHSIVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVEQTQVLKEKLIPTVPIEVRGTSSWKNWYAATEV
>A0A857D9F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa FD4|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDLNDKSLPDGPLELFAGAAVDVQSKSRSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>E0I3T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus curdlanolyticus YK9|TrEMBL
MKQDLREALQHRILTGDGAMGTYLYQMGFPVGVSYEEFNVLRPEVIGGVHRRYYEAGARL
IETNTFSANVEKLSKYGLESDVELINRAGVRLARASVGHDAYVVGAVGPIRAARRKGVRT
ATVRTALSQQIGFLLDEGVDGILLETFLDMEEMLLALRAVRQSSNVPVICQFAVEDGGST
QDGVRLFEAFSRLQGEGADVVGFNCRTGPNGIMRSIDALDGASQLPFSVFPNAGIPDYVD
GQYTYSATPAYFAATARRFADHGARVIGGCCGTTPEHIAAIAAALDGYVPALQGATVLDK
PAAPHDSGPSVSVSSAPVPPAAPPEAEEPSIVALVRQRHTVIVELDPPRDLDITKFMEGA
AALKDAKADALTMADNSLAVTRMSNIALASLVKERAGIRPLIHVACRDRNLIGTQSHMMG
LDALGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEMIKMIRQLNEGMAFSGKPLKQKAKF
VIGAAFNPNIKHLDKAVQRLERKIASGADYIMTQPVYDPALIERIAEATGHIQVPIFIGV
MPLASGRNAEYLHNEVPGIQLSDEVRQRMAGLEGEAGRAEGVQIATELIDAIMPHFNGIY
LMTPFMFYEMTVQLTEHIWLKSGRFTNEKRE
>A0A837FCY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter hormaechei subsp. xiangfangensis|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMFAADLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A6I2M580|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metabacillus idriensis|TrEMBL
MTLLNDLQNKILIGDGAMGTLLYSHGVDRCFEELNLSKPDEILNVHKAYIAAGADVIQTN
TYGANYIKLSRYGLEDEVRAINRTAVQIAKKAAAGNDTYVLGTIGGIRAFKKNAYSLEDI
KRNFREQLYLLLSEEVDGLLLETYYDLEEIKTVLEIARKETNIPIITNISLHEIGVLQDG
TPLHEGLSQLEAIGADVVGLNCRLGPYHMLSSLEEIPLPDKAYLSVYPNSSLPTLEEGRL
VYGSGEKYFAESALAFRNQGARLIGGCCGTTPLHIKAMAAALKGLPPVTEKKVKIRKQEI
SVTSAAERKYPPLQEIVSEKRSLIVELDPPKKLGIDKFLKGAKALQTAGIDALTLADNSL
ASPRISNVAVGSIVQQTLGLRSLIHITCRDRNLIGLQSHLMGLHTLGLTDVLAITGDPSK
IGDFPGATSVYDLSSFDLISLIKQFNDGLSYSGKPLGEKTNFSVAAAFNPNVKYLDKAVK
RLEKKIACGADYFISQPIYSEKQLIDVYEETRHLTVPIYIGIMPLTSSRNAEFIHNEIPG
ITLSDSIRERMAKAGDNREKAYQEGLAIAKRLIDAAFDLFNGIYLITPFLNYELTVELTN
YIHKKQTEVDERKITHV
>A1DH45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)|TrEMBL
MHVKDMLADNESAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEA
WEATEGGLRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
VITQMFYDIDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEAL
EPVKNDDAAVKEIGKRLVADMCRRLLAAGIKHLHFYTMNLAQATQAVLEELKLIPSEETP
LQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSIRDVTQIFVRYLEGKLDRLPWSDSPISGEANAIKDNLVQ
LNSRGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNP
DLTYHAVAKNRELRTNTRDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQDIMDNWYLVNIVNNDFHNTYDLFDLFNGLEVKDLDVEVGPDTVETK
SQPNGAVPEEVAIKN
>A0A5B9DR36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Youhaiella tibetensis|TrEMBL
MNIHAQQARPSRHLSDIESKLQVSFEFFPPKNDVMEEKFWDSIDKLAPLGPRFVSVTYGA
GGGTRERTLRMVSEVKSRTGVDAAAHLTCVGASRAEVDAVVQGYKDAGISRIVALRGDPP
EGVGAPFVAHPEGYRSAAELVEGIRRIGDFDISVAAYPEKHPQSPDWQTDIDNLKRKLDA
GASRAITQMFFDNTDYLRYVERVRAAGITAPIVPGIQPIHSFKQISGFAARCGASMPDWV
AKRFEGLEDDPETHALMASAVAAEQVIELLDEGVTEFHFFTLNRSNFVLALARLLGRRPG
>A0A0S3SVA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vigna angularis var. angularis|TrEMBL
MKIIEKIRDAAADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANRMQNIVCVETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVKHIRAKYGDYFGITVAGYPEAHPDVIGSDGLATAEGYQKDLEYL
KSKIDAGADVIVTQLFYDTDTFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPADIMSALEPIKDNEEAVKSYGVHLGTEMCKKILSHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALTDYQFMRPRARDKKLIEEWVVPLKSVEDIYERFRMYCIGKLRTNPWSELDGLQP
ETKIINEQLERINAKGFLTINSQPAVNGEKSDSLTVGWGGPGGYVYQKAYVEFFCSKEKL
DTLVDKCKDRISLTYMAVNKEGSWSSNVGQTDVNAVTWGVFPAKEIKQPTIVDPVSFNVW
KDEAFEIWSRGWASLYPEGDASRKFVEEVGGSYFLVSLVDNDYINGDLFAAFADF
>A0A3B7LTK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter chinensis|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLDDFN
GKGTPVAPHLSCIGDSKQRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQRFCDKARAGANAALTQFFFNPDAYFYFV
DRIQKEGIDIPVAPGIMPINNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A255GH32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enemella evansiae|TrEMBL
MSRRDPSIAELLAASDRPLFSFEFFPPASEEAARTLWQTVRQLEPLGPDFVSVTYGANGS
TRDRTINVTRQIARETTLRTMGHLTCVSQSRDDIRRVVGAYADAGIRHILAVRGDPPGGP
TAPWQAHPDGLRNATELVELIASLGDFCVGVAAFPDVHPEHHDPELDARILVDKANAGAD
FAITQLFFTARSYFELVDRVRSLGCDIPIIPGIMPVTNLRQIERFAELSGAALPTGVTDR
LLAADGPDAVRAEGVRIGTELADELLAGGVPGLHFFTQNRSRASREIHSRLQRVPA
>Q7S2B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)|TrEMBL
MEKITDKVAALPPDSNYFSLEFFPPKTAMGFANLRDRLERMARGLRPLFVNVTWGAGGST
AQKSLELAEICQRELGLTTCLHLTCTNMSRRLLDKTLEDAKVLGIRNILALRGDPPRAAE
YHDENDPEPTDDEEFSWAADLVRYIKKTHGDYFCIGVAAYPEGHAEEAHPREQSLEHDLP
YLVEKVQAGADFIMTQLFFDIDAYEHFENTLRDHPSGAFKDVIIIPGLMPIQSYQMIKRT
TKLSHAKIPPALMARLDAVKGDDEKVKMEGVAIVSEMIERIKEIKSRTPGPRGFHFYTLN
LEKAVAFIAERTNLIPPGTPDEDESAILPDIPQLRINGSSVPTRSIQDLSTRKGSIGSDP
RDRVIVANQRPSHPDYEASPSEAGLPAEPVNTRANTLAISEGEGVLGREATWDDFPNGRW
GDARSPAYGQIDGYGVSLHVTVPQALQLWGSPKTTEDINKIFIRHLKGELSAIPWSEEGF
NDETEAIRDNLIELNSRGWWSLASQPAVNGLRSDDGTFGWGPENGFVFQKAFVEFFIPSA
DWRVLEAKLKQPDMKDTVCFFATNAAGDFVSTDTINFRARMAAEAEGTAEADHRPHEPST
NAVTWGVFPGKEILTPTIIEEVSFRAWSEEAFGIWSEWAKIYGKGSDTQKLLEDLKEDLW
LVNVIHHDYLEKDGLWKLLSQ
>A0A0D6N167|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter cibinongensis|TrEMBL
MSLTHLSVELIPRTEEALRDDTAAVKTLLPAADMLNIPDLMRFPLRSWDAAALLQPVFLS
IIPHVRAIDIAPNAPLPGATQPGLQEILVVHGDPPADLSHRTYPNSTESIIRRYKKEAPH
LRVYAAFDPYRRAPWRELEDVARKKEAGAEGFFTQPVFDRKLFDLCREWLRDETVFWGLS
PVIGPRSRSYWETTNHVVFPKDFSPTLDANIAFAQTVLRELSGSEEKGAVYLMPLRVKLE
HYLPPLQDVLN
>Q4ZZ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. syringae (strain B728a)|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A2G6ASR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. P34|TrEMBL
MSLLEKLQTNVLTADGAMGTILYSYGIDYCYEELNIEKPEIIEQIHQDYISAGADIIQTN
TYSANAIKLARYGLESHVTDFNKAAIQIAKRAAAPGGQFVLGTIGGLRGIRKSDATLDEI
EKVVLEQANALLTGDPDGLLLETYYDFEELSSVVTTLKKITDVPLIAQVSMHDPGVLQNG
LSLNDALHQLESLGADIVGVNCRLGPYHTIQAFDNVTLPEKAFLSAYPNASLLDVEDGRI
VYESEAEYFGRAAVLLRDQGVRLIGGCCGTTPKHIKAAKTQLARLTPITEKIVQPAKPIV
IHEAEPAKHQPLHEKAKTERTVIVELDTPRHLETEDYIKGANLLYDAGVDAITMADNSLA
SPRISNMAMGSIVKMQHNIRPLVHLTCRDHNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELLQLIKKLNEGISFSGKPLRKKASFSISAAFNPNVRVIDRAVQR
LEKKIEAGADYFITQPVYTKEKIIDVYEATKHLDTPIFIGIMPLTNIRNAEFLHHEVPGI
KLSEDVLERMRECGDDREKSTETGLEIAKELIDTAAQYFNGLYLITPFLRYDMTLELHEY
IKKIDQQKERELTHAETSH
>A0A2I0QNQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon HGW-Altiarchaeales-1|TrEMBL
MGLLRENFNRKFIATGEVSPPPCPDKTLFAHEVEEMKPLMGRILGVNVVDGPGGRVLMSS
LGASIYMIQHGVEPILQQVVRDKNRVALQNDLLSAAIFGIENVLSIAGDHPACPASDNPK
SKPVYDMDSTTLIVMLKKLNEGKLWNGKDTNYENKNLNAKTNFFIGASLSPTSSPLDGEI
YKVKRKLIAGVDFFQTQGVFSIEPLTNFLNLYEKTIGEKISDKVLVGIVPIWSYGMFKYL
LTLPGIVVGEKFLNEVNEARKKQKETGQKGLIEEAGVNLCVDLVDKIKSLGVKGVHIMPV
GNLHAMKEIMDKAGL
>A0A2E3X5R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MIVTQQVSYAKESFDLSFELFPPKTAESEAMLWQTVDELMGFDPTLITCTYGAGGSTQTK
TLEVLDGVLGRYPTVAVASHLTCVGRTTDQLREYLREAQQRGVTSIVALRGDPPQGETTF
TPIVNGLHYAVELVALIKQEFPGFRILVAGYPETHQEAVSPEADLEHLKEKCNAGGDTVV
TQLFYDNTDFFRFRDRCSSIGITKPIIPGLMPVTNFKQIKRIATLCKARLPNSFTHALEK
AGDDADAQFEAGVDYASKQAEELLSNGIPGMHLYVLNKSPAAIRVLEQVGMTRP
>A0A6C0XHM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter schindleri|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLADFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADNFDADIKRFCEKAHAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A356QM87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MVVTQQVSYAKESFDLSFELFPPKTAESEAMLWQTVDELMGFDPTLITCTYGAGGSTQTK
TLEVLDGVLVRYPTVAVASHLTCVGRTTDQLREYLREAQQRGVTSIVALRGDPPQGETTF
TPIANGLHYAVELVALIKKEFPEFRILVAGYPETHQEAVSPEADLEHLKEKCNAGGDTVV
TQLFYDNTDFFRFRDRCSSIGITKPIIPGLMPVTNFKQIKRIATLCKARLPNSFTHALEK
AGDDADAQFEAGVDYASKQAEELISNGIPGMHLYVLNKSPAAIRVLEQVGMTRP
>A0A378NVH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megamonas hypermegale|TrEMBL
MTRISVELVPRDVEVLKEEVKTIKEKLSDVDFINIPDLLSCDTRSWDGANIAKAYFDDVV
PHLRAMDFDFTKELPIKDKLREYNIKEVLVIEGDPPQSMLYQVYPTISTDIIKKFSEEMP
EITVYAGIDQYRSSMKEEEYRIRRKQLAGAKGFFTQPFFDMRYLEMYADLLDGLDIYWGV
SPVLSERSVSYWRNKNNVIFPKDFEPTLEWNIEFARKVIDFARKHNHNVYLMPIKAKIMP
YLEGVFAK
>A0A5B0KK44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum brasilense|TrEMBL
MTASLSAPPSISFEFIPSKTETMEQGLWQSIRRLAPLAPIFMSVTHGAGGSTRERTHATV
CRIQDETGLPAAVHVTCVGATRDEIDAIAHSYWNAGIRHLVALRGDPSDMPGGSGRCEPS
PGGYAYAANLVAGMRRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITHFF
FDNDVYFRFLDRCAAAGIHVPVIPGILPITNVARAVEFAAKCGASMPARLVETFEGLDDD
PETRRLVAATVAAEQCQALQAQGVRDFHFHTLNRSDITLATCHMLGIRAAVPAP
>A0A2E3RGW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MKISDAYEGGRFGLSFELFPPKTEAGEEALFDHLERLIAFGPSYITCTYGAGGSTQAKTL
EIIDRVRKVYGCTVASHLTCVGLSRSELIHYLKEALQRDVKNIVALRGDPPQGSDSFEPP
EDGLRYASELVTLIRDAFPEFGIAVAGYPETHREAESPESDLENLQRKITLGGDLVITQL
FYDNADFFRFQQLCSDRGIGVPIVPGILPVTNLAQIQRISGLCGATLPPDFEAELSACGE
NADEQFEVGVRFAIEQVRDLIDRGVPGIHFYVLNKSDATARILESVSVPSHA
>A0A2D2M1Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. HLS-6|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSTNDLRTLLAQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIRKESGDHFHIEVAAYPEMHPQARNFEDDLANFARKVQAGADSAITQYFFNADSYFY
FVERVQQLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDAKSIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A371K6C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter silvisoli|TrEMBL
MSPISFEFYPPKTDEQRAQLDKTAAKLKARKPSYVSCTFGAGGSTLSYTPDTVRHLRAEH
GFDAAPHLSCVGGTRDEIRQLLAQYRELGCRRLVTLRGDLPSGMARAGDLRYANELVEFI
RAETGDHFHIEVAAYPEMHPQARDAHADLENFKRKVRAGADGAITQYFYNADAYFRFVDD
VRAAGLDIPIVPGIMPIANFSQLRRFSELCGAEIPRWIEQRMMAYGDDVDSLREFGADVV
AQLCRRLVEGGAPGLHFYTLNLSKPTLSVLSRLA
>A0A1I7HDK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. M55|TrEMBL
MKVSDLYKEGRKTLSFEIFPPKKDKALEAIDETLDVLCELKPDFISVTFGAGGSVGSNNT
IEIAKKIKHKCSVEPVVHLTSLHYDKNEIDEFAAALKNEGIENILALRGDRNANIPEKDD
FHYASDVISYMKDKYDFCVLGACYPEMHPETATEEDELNNLKTKVDSGAEVLLSQLFFDN
DKFMNFREKSKAKGIEVPMIPGVMPVINAAQIKRMLTMCNATFPERFKKITDKYENNKEA
LFDAGMSYALSQVIDLLVSDIDGIHLYTMNNPVVARRICEGIKNII
>A0A7L2YM07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jacana jacana|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYESDLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWREDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7C1TU07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MAVNEKNLGCDPVGLSGDLEVSFEFFPPKTEKMEETLWSSVQRLAPLHPRFVSVTYGAGG
STRERTHATVARILKETDLVPAAHLTCVGSPRGEVDDIARQYWDEGVRHIVALRGDAPED
AQGGAQGGAQGGAKTYKPHPEGYAYASDLVAGLKRVADFEISVAAYPETHPEAESPEADL
DYLKRKIDAGATRAITQFFFDPDVYLRFLDRARAAGVTAPIVPGILPVTNFSRLLKFSAN
CGASVPDWMGRMFEGLNDDPETAKLVSATLAADQCRKLYAHGVKQFHFYTVNRADLTFAI
CHILGVR
>A0A199NZ16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas translucens pv. poae|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKTYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQASDALSDLRHFKAKVEAGADGAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQALGDDGDAIREFGADLV
AALCQRLLAGGAPALHFYTLNLAKPTTSVLSRLE
>A0A3S0KPS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella atlantica|TrEMBL
MGFHHAQHATSLNQSLAELNGDINVSFEFFPPATPEMEKILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETDLVAAPHLTLVDASDEELKELAKHYWNSGIRDIVALRGD
LPEGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDALNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFKQLKRFAGMTNVSIPGWLHKQFE
GLDDDPTTRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A0N1BK26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomonas sp. AAP25|TrEMBL
MTLSLKQLAEAREALGTPLFAGLAGDVEVSFEFFPPKTEKMEETLWDTLTTLAPLKPKFV
SVTYGAGGSTRERTHATVARIAAETAIPAAAHLTCVDATRDEIDEIAQNYWNAGVRHIVA
LRGDPPRAGEKFSPHPGGYANAAELVTGLKKVAPFEISVAAYPETHPDADCADSDIDNLK
RKIDAGADQAISQFFFSPEAFFRFRDAYTKAGITKPILPGILPVSNVATTRKIAGMCGTA
IPQWMNDLFEGLDDHPTTRQLVAATVAAELCRRLYSGGVRHFHFYTLNRAELSFAICHLL
GLRANRHAQAAPVLQENAA
>A0A1S6FNM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. LM7|TrEMBL
MSIVDPLAAPLFADVAGDIEVSFEFFPPKSEKMEETLWESIQTLSPLGPRFVSVTYGAGG
TTRERTHNTVARIARETAIPAAAHLTCVEATREEIDQVAEEYWAAGVRHIVALRGDPPRA
GEKFVSHPGGYENAAALVAGLTRLHPFEISVAAYPECHPDSADATADIDNLKAKIDAGAT
RAITQFFFEPETFFRFRDDAAKAGITAEIVPGIMPVMNFASVQRMSAMCGTDVPVWMGKL
FEGLDDHPAARQLVAATLAAELCRKLYAGDVRQFHFYTLNRAELSYAICHLLGLRPKVGA
ELVAA
>A0A4V2T5Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. (strain PP-F2F-G36)|TrEMBL
MSTRTLYPAERGDLRLSFEYFPPKSEEMDTQLTRTAATLNAYAPEFVSVTYGAGGSTKAR
SLTTVRRLIDDCSIPGTASHLTCVGATRAEVDAVVEEFAAAGVRHFVALRGDPQGGIGAQ
YQPFPDGYENAAALVAALSRSGRFQISVSAYPEKHPESSDVDADIDMLKRKVDNGATRAL
TQFFFDNNDFERYLERVRKAGISIPVVPGILPINQFGQVSKFAGLCGARIPEALSARLAH
LDESPEERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFKRTDEAVVE
GAAA
>A0A0A7LGZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp. DG25B|TrEMBL
MKVTDHLLQAKGKTLFSFEVLPPKKGENIQSLFTNIEPLLEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFLPDPDGHSYACDLIGQVADLNKGSYLDEEQDDTWATNFCIGAAGY
PEKHFESPNYAADLRYLKHKVDRGADYIVTQMFFDNEQFFSFEKRCREAGINVPIIPGLK
PLTAKGQLTMLPRSFYLNIPEALADAVHQAPGNEAARQIGIEWCINQSKELMAHGVPVLH
YYSMGKSDSIRQVASALF
>A0A6N6N3T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio senegalensis|TrEMBL
MPIPRLIEEDRPFISLEFFPPRNEDALPVFLDTVHRLARLKPLFAAVTCGAGGGGATGTL
RTARDLCEEKGFTVMPHMTCVRNDPESIAEQVREIRSCGIRNVLAVRGDFPDGVDSAPKG
LRHATDLVRTVRQQDPDLCVGVAAYPDAHPESESIEQDIEHLRQKFEAGADFAVTQLFFD
NRKYFDMVERLADKGCTKLVIPSVLPIRSFGQVRRLMGLCSTPIPGKLLAALEAAHASGG
DGAVRDVGADYAAAQVRGLVDAGAPGVHLYPFNRAGLCLDVVERAGLMPA
>A0A1F9MG38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYD12_FULL_50_9|TrEMBL
MKSGSRLERILTAGQFAVTGELGPPKSADPEVVRAKARILKGHVDAVNITDCQTAIVRMS
SIAAGLLVLNEGVEPVIQMTCRDRNRIGMQSDVLGAAALGLKNLLCLTGDHQKFGNHPGA
KGVFDMDSIQLLGMIKGMRDNRKFQCGEDIKSAEPHLFLGAAANPFAGPFEFRAARLGKK
VSNGADFIQTQIVYNVEKFARFMEMVRDLGLDQKVFLLAGVTPPKSLGMARYMKQFVPGL
EVSDDVLKRMKDAKDKEDEGINICVDIINQVKEIKGVAGVHIMAIEWESAVPEIVKRAKL
GPRPLFDDEQNRLEISQSAIIIREEGRAEGTESPIAKADAILTAARLEAEKIVKAARQQA
SLNLGQAVGETTAYDAGEDEMNERERQMALEAVRQGLNSLKKAFGLSDEQMDALAKFAGA
EAILAREAAKTTQPISTTTPVPVAAPAALAPTKSADEEKKTLELKAAQDAKMAAEVKAQA
EAKAAEEAKKLADVKAADDAKKAAQVKADEEAKKAAEAKSAAEAKKITAPKAVTQPAPTA
KAAGIAATELKAESTPLQQRCSKIPADHYTTPYNGKIREIALGSGDQAVTVGGATTLPFQ
LFEGASLRKPLIAMDVLDVNPDEWPVSLSRYFEGVLDNPAAWAKKCVNEYAADAICLSLI
STDPNGLNRPAAEAAKMAAQVVKDIDVPIIVWGCGNAEKDTETLRELTAIIGDKKICLAP
LSDANYRSLGATGMAFGHSMVASSPIDVNLAKQLNILLENLGVPLSSVMIDPSIGALGYG
IEYSYSVMERIRLAALTQKDEKLQVPFICNLGREVWKTKETRLPSDGILGDQENRGVLME
AVTATCMLVAGGEVLVMRHPRSIALVKSLIDGLTK
>A0A1Y4R7L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilimicrobiota sp. An142|TrEMBL
MKISEILKKKATISFEVFPPKNKEGDISSIYYTIEELSQLNPDFISVTYGAGGSTKGKTV
EIASTIKNQYNIEAVAHLTCISSTESEILDICQQLKDNHIENILSLRGDYPQDGLQHELS
FHYAKELNTFISQHFPGDFCLSGACYPEVHQEASCLEDDLKALKEKVDAGAQYLITQIFF
DNHYYYRLVKEARKRGINVPILAGIMPVTHSKSLLRTAKLCGCSIPYELSTMIESYYHYP
EAMKEIGINYATHQIIDLITNGVDGIHIYTMNKPEIAKAIFQSIPTVLKELNHE
>A0A6N6MUB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. YIM 132548|TrEMBL
MPASTYRASREGCRPIRVSFEFFPPKTEEMEKTLWSSIERLAPLHPSFVSVTYGAGGSTR
ERTHNTVARMVRETNLKPAAHLTCVNATKDEVDEVVRAYWEAGVRHIVALRGDPAEGVGN
AYAPHPGGYQQTCDLVAGIKRIGDFQVSVSGYPEKHPEATSLDADIDALKAKVDAGADRA
ITQFFFENDVYLRYVDRVRARGIDIPVVPGILPVQNFKQASNFARRTGASVPEWLAHRFE
GLDDDVDTRRLIAGAVAAEQVLDLVDRGIHDFHFYSMNRADLVYAICHLLGLRAEKPAVA
AERVAA
>A0A1R7QFH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MCRREKPYDSSSRHLVISSSRHLVISSSRHLVISSSRHLVISSSIFDLYYNSSFLILWII
SPVMSLLAQYFAQQQFCVLVEYLSAHQAQWSVKTQFAGFPACMTLADRVHADDDEAPLQV
AKQYPQEIEKVIHFSGKARDIQDFEQFLRDAKTRGQKNLLLLTGDKLKQHCYSHDLEPRT
RYLESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDM
AALQDAHAFLARHQYAQKMLACVMPLTLARAKFMLKHKVAGIVITPHMLQVLQQEKEQGL
SDRVYVRCALQILMCRHLGFAGVHLSACHQPEEQVLLESYIEEYRHLSFAECEQLWNTLW
QVQTSTEFHPKLAYYSRPATSSQIIKYQHLHLMHDVLFESKLAKGVGRFIFNFNVWDRSR
AKQALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDR
ECIHSVKARLAKAVGQTKILKEKLIPTVSIAVRGTSSWKNWYVEAAG
>A0A6I2USE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas montiformis|TrEMBL
MKRVSVELVPRDEESLRGELKLLQRHQDRIDVINIPDLLRFEIRSWQGAAMAEDYFPQVM
PHIRAMDIDLSQELPMKEYLRMHDIREVLVIEGDPPQRMNHAVYPTESTDVIRKFREEMP
EVTVYAGIDQYRSSMRDELYRIHRKVQAGAAGFFTQPFYDMRFLEIYADMMAGMDVYWGV
SPVMNTASQSYWERKNNVVFPSSFRPDLSWSIAFSHQVMEWAEQRDASVYLMPIRTNLEA
YLEGVFGGSGQSHEEAAGR
>A0A7S8XIU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MSLLAQYFAQQQFCVLVEYLSSHQAQWLVKTQFAGFPAAMTLADRVHADDDEAPLLVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDTKTQGQKNLLLLTGDKLKQHHHSHDLEPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMTAL
QDAHAFLARHQYAQKILACVMPLTLARAKFMLKHKVAGIVITPHMLQVLQQEKEQSLSDH
VYMRCALQILMCRHLGFAGVHLSACHQPEEQSLLERYIEEYRHLSFAECERLWNTLWQVQ
TGTEFHPKLTYYSRPATSSQIIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDRSRAKQ
ALLKTEHLSKHVVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTKILKEKLIPTVSIAVRGTSSWKNWYVEATG
>A0A6N6N7C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio senegalensis|TrEMBL
MRIVDLIKQESPFLSLEFFPPKNEEAWPSFFGVVEKLKELNPLFASVTYGAGGGTQSNSL
EIARRLKQDYDLEPLAHLTSVGATSSGLTEFVSKLEEAGIENILALRGDAPKDVENFDFS
AQEFQYATDLVTFLRSKFKKMCVGVACYPEAHPESPSVSFDLAMSKLKCEMGGEFMVTQL
FFDNRIYFDFVDRMKSMGVNVPVIPGVLPIMSIKSAKFILSLCGASIPGSFLSALEKAHD
EGGDDKVYEVGMAYAIRQAQDLLDKGAPGVHLYTLNRAKACLEIGNSLKF
>C5BTQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Teredinibacter turnerae (strain ATCC 39867 / T7901)|TrEMBL
MTDTNNDISLSFEFFPPKSDAGREKLQAVRTELNQLKPDFFSVTYGAGGSTRENTKGVIK
AMRAEGLSVAPHLSFGGDDEDTMIAMIEEYKAAGVDRIVALRGDMPSGMGAAMQLVYANE
LVAFIRKHFGSHFELCVAAYPEIHPEAKSYLQDIRYLKGKFDAGANCALTQYFYNPDSYF
YFVEECAKEGIEGPIIPGIMPITNYQNIARFSDACGAEIPRWIRKRLNDFGDNQESLQAF
TTDLVTELCATLLENGAPGLHFYTMNQVEPTRTILTNLGLVD
>A0A2N7TGE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas heilongjiangensis|TrEMBL
MQRLVTVEAVGRIREVLAAPRYELLPLKGMQEVARHLPAGAVVTVTCSPRHGLERTLEAA
EWLAVAGFQVVPHIAARLVRDPAHLRRLVARMLAAGIDDCFVVGGDAERPAGEYAGGAEL
LEAMAAMSSRPSRLGVPAYPEGHHRLDDATLQRVLDAKAALADYAVTQMCFEASTVLAWL
ERQRRSGMTLPVYAGIPGVLERTRLLSVAMRLGLGTSTRVLSRRTGLVGRLLQPAVYRPD
DLLQGLLPAVGDGGIAGLHVYSFNQVGATRAWLDAHHAAHCRGLGLATLATPEPAPAGPP
G
>A0A435IYW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.001.04.1.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQAPTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYIDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAEQSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A6WZN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella anthropi (strain ATCC 49188 / DSM 6882 / CCUG 24695 / JCM 21032 / LMG 3331 / NBRC 15819 / NCTC 12168 / Alc 37)|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKSEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDVKPAAHLTCVDATREEVDRVVREFAALGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPSWLAERFE
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTEAAL
EVA
>R0B425|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] clostridioforme 90A6|TrEMBL
MKTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTREDVLLILEQLKEQKIENILALRGDRVPDREPAGDF
RYASDLVEFIKLHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFRERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFISVMERYGDNPIAM
RDAGIAYAVDQIVDLVAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>I4CD85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1)|TrEMBL
MKITELFAGGTYVITSEVGPVKGCMRDLGDGKVPRCLEEADILKNHVHAINVTDNQSAVM
RLGSLAASVRLKERGVEPIYQITCRDRNRIALQSELLNACSLGIDNVLVITGDHTTLGDH
RSAKPVFDLDSVQLLRIATQMKNGYDMAGNQLTQATDFALGAVVNPNFEPLDLQLIKMEK
KIAAGAQFFQTQTVYDAALFEKFIRKTEGFGVPIQIGIVLIKSAKMAEFMNRNIAGITVP
DRWVKRLGDVPTEKAKDLCVEMTSEFFKEVAPMTQGVHFMPLGWSDVVPRIIDASLVGKA
S
>A0A4Q2TXJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciceribacter sp. F8825|TrEMBL
MSPDINPIDPGLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPHDVYERASIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRTMRDEAKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIAAGAQFVQSQYCYDVPMLRDYMQKVRDLGLDEKCFILVGVG
PLASAKTAKWIRSNVPGVHIPDHVIARLEGAQDQKKEGKQLCIDIINEVKEIAGVSGIHV
MAYRQEEYVAEIVHESGVLKGRRPWKREPNPVDALVAERLEAIREEKVEDQQELAGIAAQ
HPH
>A0A0F4NIG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio galatheae|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELIQIADDYWANGIQSIVALRGD
IPPGGGKPDMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMVKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A0L0T1R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allomyces macrogynus (strain ATCC 38327)|TrEMBL
MKVIDKLRRAHEQGRQAWSFEYFPPKTQQGVLNLYDRLERMYALAPEFIDVTWGAGGTTA
DLTMDICHVAQAVYGLETCMHLTCTNMPRDKIDAALKQARDIGIQNILALRGDPPRGQAE
WTACDNGFAYAVDLVKYIREVHGDWFCIGVAGYPEGHLENPDKEADLRHLKAKIDAGADY
IVTQMFYDVDLFLNWVRRCRAIVCRGKISALPWSDQPLAPESRTIASLLAQLNARGCLTI
NSQPPVNGAPSTDAVHGWGPRGGYVYQKAYLEVFVSPQVLDALANRLATTPDAEFVSFHA
INRAGDLRTNEADPNSPNAVTWGVFPGKEIVQPTIVDLTSFMAWKDEAFELWTQWRNVYP
ASSPAYTNIDRVASDWYLVTIVHNDFHQPESVLVNLLLAAAADVDGVPVEKTPSIVEDLL
ASEPASVPEVASSTPSSPPAANGIKKSASGAPAETAVAPAIEPASRPATAASKATTNGVA
TKLSTVSACSPAAPAVTAVSS
>A0A1X0UF64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 1163|TrEMBL
MVDRLRASTESKIPFSVEFSPPRDEAAEARLWRAVREFEQMQPAFVSMTYGAGGSTRDRT
VRVTGEISENTTLLPVAHLTAVSHSIDELRSMVGAYADRGISNILVLRGDPPGDPLGDWT
KHPQGVEYAEELVTLVRELGDFHVGVASFPEGHYRAVDLEQDTLVLVNKLRAGAEYSITQ
MFFDVEDYLRLRDRVAAFDPEQACKPIIPEIMPITSLRTVRRALSLSGSALPSDIDDRFT
RAAGTGAEEDRAAVREVGIELATSMCERLIAEGAPALHFITLNFARATREVLTNLGLCAA
RV
>A0A3D1H0U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp|TrEMBL
MNIADFLNKEGQKRGFSFEVLPPLKGNGTAALFRTIDSLKEFDPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTIAIAGAIQNKYDIPVIPHIICSGASKEDIEYELLDLQFLGISN
VLVLRGDKAKEDRQFTPTLNGHAHATDLLKQINQFNEGFFMDGTPIKHPGEKFYCGVACY
PEKHEEAPNLEQDLQHLKEKQDLGASYAVTQLFYDNQKFYDFVERARKMGITMPIIPAIK
PFAKLSQLTMVPKTFHCDIPEELAQEVLKCKTDDDAKTLGIEWTTTQVKDLFEHGYSHVH
FFTVSAVESVKQIAKILF
>A0A6M4JF47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis (strain 168)|TrEMBL
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTRAKEFIS
VHHERTEPGLDEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMAHAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>A0A7J9E5L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium trilobum|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILALGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DALVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KGEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A6J2ENT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zalophus californianus|TrEMBL
MDHPTPKVLPARPRGPSLGMWALETGRVRFSVPPSISRNPAMVNEPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQEQITG
YLHKAKRLGLKNILALRGGVEAALYSLGSCFLEGLFCPYPVGDQWEEEEGGFSYAADLVR
HIRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFV
KACSEIGVTCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIE
QAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKM
WGEELTSEESVFEVFARYLSGEPNQHGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGIL
TINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHI
VDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYE
EESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPTPERGEEALGSCTV
VSLP
>C0BT82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudocatenulatum DSM 20438 = JCM 1200 = LMG 10505|TrEMBL
MFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVSEYGI
PSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFEHASDLAVYIRQ
QRPDMKIYGACYPEKHPQSATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLDKARA
AGIDVPIEAGIMPVMNAKSVLNMSNKCQSKVPEKLGIMLDKWGGDKALLKEAGIAYASEQ
ICELVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>I2Q3H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp. U5L|TrEMBL
MRIGELIEAKRPFVSLEFFPPKEREAWAGFFDVVERLLPVHPLFVSVTYGAGGSTHAHTL
EIVSRLKTVYGLEPMAHLTCVGASKEKIRGFLDGLAAAGVDNVLALRGDPPKGQEQFVPD
SEDFQHASDLVAFIRREYPALAIGVAGYPECHPEAPSARADLDFLRRKIALGGDFTVTQL
FFDNDCYFAFVDKVRGMGVTVPIVPGVLPVMSLASVKRLSSLCGASLPPAYLAALEAADA
AGGPAAVAEVGIAHARKQAQDLIDRGAPGVHLYTLNKAEAVLSIVSGLTM
>A0A4R3JNA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Primorskyibacter sedentarius|TrEMBL
MTRPAISFEFFPPQNLEASFRLWDTVQVLAPLGPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLPVAAHLTCVNATREETLGIARDFAAAGVSDIVALRGDPPKGADRFEQHPGGFADSC
ELIAALKETGDFTIRVGAYPDKHPEAADNAADVAWLKRKFEAGASEALTQFFFDVDSFHR
FRDDCAAAGIDTTKIVPGILPIENWKGAVRFAKRCGTPVPNWVVDAFETAERDNREDLLA
TAICTELCSNLLDAGVDKLHFYTMNRPELTRDVCHALGVTPAVRLENVA
>A0A416WC22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. AF15-50|TrEMBL
MNIADLFKKKTVFSFEVFPPKKESGVETIYKTLEELKQLNPDFISVTYGAGGVGVANATT
VDLCSKIKNEYGIETIAHLTCLYNTKEDIDSILEELKEKGIDNILALRGDVNPNFELKHD
FRYASELTEYIMSKNMGFNVSGGCYPEVHQEAESMIADIKNLKKKIDAGADHLISQLFFD
NNAFYDFIEKVRIAGIDVPIEAGIMPVTNKKQIERMVSMCGASIPAKLSKVLQRFGDNPE
AMRDAGISYAIDQIIDLVANGVEGIHIYTMNDPYIAGKITKSVESIIKN
>A0A0Q9MK20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Soil736|TrEMBL
MSPPSLIDTHPNLSDTAPVALSYELFPPRSPAAAETLWTTIRELETTDPDYVSVTYGASG
SNRDTAVELINRLVLETTLRPLAHLTCVGNTPLELAEIIGELLDAGVRGILALRGDQPKD
SGEPVSGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFRTEQYADLITRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAPELIERLAAADTDADRLRIGVSATVDLANAALEAGAPGLHLYTFNEHQSALEVLDKLS
LARPARSASRLNAIARRQLAS
>A0A4Q3N5T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagaceae bacterium|TrEMBL
LSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSGPKGFHFYTLNLEKA
VAHIVERCKLIGAVNNVTVEDHDTPVANGNGDKKAKARRRSSIANSAPQNRVVIDKTSRS
ASSGSATFEAFDDAAGVPGEDPPSRKDALAISEGEGALGREATWDDFPNGRWGDARSPAY
GEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAQAYDAEIALVRDTLSA
SQAAHWVQYLAAWDAASA
>J0XEF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schaalia georgiae F0490|TrEMBL
MMPTRRSELAAPFWETAAELLCVRPDFMSVTYGAGGKDRDNAREVVHRLVRDTPIQPIAH
LTCVGNSTADVVATVYDYFDCGVRTFLALRGDPPADQPDWQPSPDGVRSATELIHLIRTV
ERRRCDAHPGEMLRGAFKPLTIAVAAFPAGNPAAGTTPD
>B9L912|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nautilia profundicola (strain ATCC BAA-1463 / DSM 18972 / AmH)|TrEMBL
MLKEKLKDKYITLETTPPKLPTVDLMIEKIEKSEAYKYIDGFSTTDCPLSKLKYNSIIAA
YKLQEKFKKPVIATMSMRDRNKIALQSDLLGANDLGVTHILALTGDPANMSDQPKAKAVV
EGSSILLLEIIRAFNNGMDYAGKEFKIKPKPITPFAVSNSYAKNFSSIERRIFKKVQNYA
VGIITQPVYDINIVEKLLEIKEKVISEFNDERKEAEIILGFFPITKLKTAQFLHAHVPGI
YVPEEWIEKLIKAHKISEDEEYKVGMELSRNLFQQLLKKHPKIHIMTANRFEIVKEFF
>A0A374WYB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. OM04-5|TrEMBL
MRVDEVFKQAASQGTAPISFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRSHADIAAKIDEYRSAGMENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDVGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A1H0VDP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus singaporensis|TrEMBL
MKLSEKLGNKFVITTELGPVKGVLTDESLEKAESYLPLDGINVHDCPMGNLRINSVAMAG
LIQNKLDIEGIPHFTCRDRSLLGTQADLLGAHGLGIRNILVTTGDPPKHGPYPSKPVYDY
NTLELLDLIGKMNSGVDFNGKEFGGRTDFTIACTARPTARNPERELERMSRKIAAGADFF
QTQVVYDSEKTVSFLKEARKLGKPVLIGLMPLKSVKMAKFMNNNVEGIDVPEDVISRMEN
DGATGIDITCDLIREIAEYADGIHIMAMGDVAGTNLIIEFTNALVDNRR
>A0A6G6QCT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia sp. 1709051003|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSEEMEQTLWKSIDRLKNLKPQFVSVTY
GANSGERDRTHSIIKDIKDKTGLIAAPHLTCIDASPEELKAIARDYWNNGIRHIVALRGD
LPDNSRKPDMYAVDLVELLKGEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPAWMSKMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A396NZ99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM30-24|TrEMBL
MNLREYLKTTNLITDGAFGTYFAAKYQTQDIPELANITAPEKVKKIHEEYLNAGAKFIRT
NTFASNTETLQEDFAEVEKNIQATVEIARDAVNGRDAWIAGDIGPIPVNGAEDAAAAADE
YYQIAKTFAERGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIAAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIREMSSWDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLSVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTEEDAARLRRIKEETGAKILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>A0A1F3LM04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWF2_40_14|TrEMBL
MSVIEKIKNAKGPLFTFELLPPLKGHSIDKIYAAIDRLVEFNPAYINFTSHRNETSYRER
PDGLVERRLTRVRPGTIALAAAVKYKYNITVVPHVLCGGFSKEETENALIEMNFLGIDDV
LALRGDPVRGTRSFIPEKDGHSYASDLITQIVNMNNGQYLEPSLVNVTPSSFCIGVAGYP
EKHFEAPNLQIDMDNLKKKIDAGANYIVTQMFFDNQKFFSFRDECKKAGINVPVIAGIKP
ISALNDINLLPQTFHIDFPSDLVAAVRKCKTDQEAREVGIEWTTMQSKELIQEGVPGIHY
YTLGRSDNIARIVKASF
>A0A0H3LLF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)|TrEMBL
MTQSTAPAFSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRT
LRNLGCDAAPHLSCIGATRDQLRDILAAYREQGVRRLVALRGDLPSGMGGDAGELRYASD
LVAFIRQETGDWFHIEVAAYPEMHPQAESPSADLAHFVNKVQAGADAAITQYFFNPDAYF
DFVERAQAKGVAIPIVPGIMPITNHTQLVRFSEMCGAEIPRWIRLRLAEYGDDKASIRAF
GLDVVSELCQTLLENGAPGVHFYTLNHAEATLGIWKALNA
>A0A3E4P092|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. 20_3|TrEMBL
MKVIDLIRDSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIVHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A2S4Q6P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1A6KUN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. UCD-FRSSP16_10|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTNLIAAPHLTCIDASRDELFNIAEDYWRNGIKSIVALRGD
IPPNGGQPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQASRFAAMNHVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQAVAI
>A0A5C8G151|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira aalborgi|TrEMBL
MNSVENFINKLENEKEFTFTLEVTPQAKFDLGYLVEKIKSSNIEKYIDAFIIPDSPFANL
KISPILSSLQLSQRLKTEKPFIITQTMRDKNSIALQNDLIGANYFDIRMVLALTGDPVVN
GNQKQAKGVFEGNSELLIRIIKNLNEGKSAGNFIFKEPLKKIYPFCSINSYSKNDEMLKV
RLSKKTASGVKAIFTQPIYEVETLKKFLNWIDEMPLKEMKLKEKPILFPGFFPVLSYKTA
YFIYYKLPGAYIPEEWLNKLKDASEKSAEEEKKVAFELSSNLFKDMLIVCKKMHIMSMNN
YDFVADLLKHIC
>A0A063BES7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. lig30|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLMPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQAKSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGVDV
VTGLCRRLVDAGVPGLHFYTLNSAAATRAICEGLGL
>A0A2S6R2F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha10_Bin2|TrEMBL
MAESDSLFEPPQAVPGDRLGAAVCAPALSDISVSFEFFPPTSDKIAEQLWNAIVRLAPLK
PEFVSVTYGAGGSTRERTFDTVERIMKDTDLTPAAHLTCVGDSRGAVDDAARRYWDAGVR
HVVALRGDPPEGTDKFEAVKDGYSYAADLVEGLQRVADFEISVAAYPEIHPEAKSAEADL
>A0A659V9B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.158.01.1.1|TrEMBL
MSIRHQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQIF
LGAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>A0A3N4I3H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ascobolus immersus RN42|TrEMBL
MHISQKLLQAQESGKPIFSFEYFVPKTAQGLQNLYDRIDRMHSMGPSFIDVTWNAGGRLS
NLTCEMVNMTQSVYGLETCMHLTCTGMPKSKVDDALKEAYKSGCQNILALRGDPPREKEK
WEAVDGGFRYAKDLVRHIKNEYGDYFDIAVAGYPEGCDDQPDADLLLEHLKEKVDAGATF
IITQMFYDVDNFLEWVKKCRAIGITVPIVPGIMPIQTYASFMRRATWTKCKIPERWMELL
EPVKNDDVAVREIGKDLIAEMCQTMIDNGIMHLHFYTMNLATATSMVLEKLQLLPSVVKS
PPSLPWRQSLGFNRKEENVRPIFWKNRTKSYVARTQEWDEFPNGRWGDSRSPAYGELDQY
GIGLRGSNEQCITLWGEPKKLSDVTSLFTKYVQGKLNSLPWSDQPITAEADTIRDALISL
NERGFLTINSQPAVNGIKSSHEVYGWGPKNGYVYQKAYLELLVSPEALAELITRIEREEQ
LTYYAVDKSGNLHTNSPEGPNAVTWGVFPGKEIVQPTVVETISFLAWKDEAYRLGEDWAK
VYPAGSESRVLIETMMDTWSLVNIVNNDFHDTHSIFRLFDGLEVSSVSADGITNGVEHLN
IAEDVHPTPVTTNGV
>A0A2K4II81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MPR-ANC1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A840D0W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dysgonomonas hofstadii|TrEMBL
MRTVTELINNKDKTAFSFEILPPLKGNDIEKVYGIIDKLIEFDPKYINITTHHSEYMDKV
MPDGSVKRVNIRKRPGSVAIAASIQHRYNVMAVPHMICKGFSKQETEYALIDLNFLRVHN
LLLLQGDTKRLAPEQIYPNRNEYATDLQLQVNDFNEGISEDGSTFEKNLTPFAYGMACYP
EVHEDAESAESDIYYMKKKAENGAEYFVTQMFFDNQKYFSFVEQCRKAGITQPIIPGVKP
IVLMSQLEVLPKIFRSSIPEELAIELRKCKTDEESKEVGVEWGIKQCKELIAHGVPSLHF
YSLMATESVARIAREVY
>A0A1S6IXS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforamulus ferrireducens|TrEMBL
MKISALFKEKKPVISFEIFPPKTTTPIETIFNTLEEMVKLKPDFISVTYGAGGSSRDRTR
EIASRIKNQYKVEALAHLTCVGHTTAEIDKILKDLESENIENVLALRGDPPADQPDYDFS
ACDFQYASDLVRHIKNCSNMSVGAAAYPEGHVHCKRLSEDMHWLKYKVDQGVDFLVTQIY
FDNRIFYNFIENARRIGINCPVSPGIMPVLNAKQIKRMITLCGASMPAKLLILVDKYGDS
PEDMEKAGIEYASRQVQDLLDNGVDGIHLYTMNKYQQITEILRNVGKA
>A0A6M7UJ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium erdmanii|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILNETSLTPAAHMTCVDAARHEVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPEGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFIQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A835YII2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tribonema minus|TrEMBL
MKIIEKIKHAEAQKQVFYSFEFFPPKTAAGVENLHLRMERMAALEPLFIDVTWGAGGSTS
ELTLAISAAAQKYLGVQVLMHLTCTGMTVEQVKEALIKAREAGIQNILALRGDPSKGSAA
WEAVTGGLANAAELVKLIREEHGDYFGIAVAGHPEGHIDSTSTEQELLHLKDKLAAGADF
VITQFFYDPAAFLTYVEHCRAVGITAPIIPGIMPIQSYTAFKLMTDYCKTKVPLAIREAL
EPIKDNDEAVRAYGVTLGADMCRALVRAGVPGLHFYTLNLEVAVTNILKATGYSESAALR
RAYPWRPSSDARRASEDVRPIHWANRPHSYIARTEVWDEFPNGRWGDGRSPAFGQLSDSH
FYRFAAGSREDRRGLWGEAPIEESEIYEVFAAYVEGKIPALPWSESPLHLESALIRARLA
RINRAGYLTINSQPRANGEKSDDAAFGWGGPGGRVYQKAYVEFFTSPEGLERVLSVCEGR
PHLSYYAVDAEGDCRSRGGRGTTALTWGVFPDKEVLQPTIFDVETFLVWRNEAFNLWTHL
WATAYLEDSRSAALLHDVHDTYYLVAIIDNDFFQDDLWEGFIDDLLAIPAAANGT
>A0A0M2NCV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Christensenella hongkongensis|TrEMBL
MNLFGKSGILLFDGAMGTYLAAKYEGSVARCELENIKNPQRVIDAHREYVDAGADAIKTN
TFAANTFSMAADMETVLQVIDAGCDCAKKAAGPHTHIFASMGPILHADQQRCDSERRAII
DRFVENGVKCFLFETFDQAPVLADAARYVKSVAPDSYVITECSVAPDLYTQSGVSAQGII
DDLHEVGEIDAYGFNCICGPLHMVNVVRSTDFYGKTISIMPNAGYPTVVGGRTVFKSTPD
YFAEQLKKIRREGVQILGGCCGTTPEHIRAVKQALKSMEGQAYPYKPKKKGETVHAERKS
YTQKPIAVELDSPLDADHSFFVQAAKDLHAAGADYITIADCPIGRARADSSMLAAMLKMQ
YGIEALPHLTCRDRNLNASKALLLGLSMQKVRNLLVVTGDPIPSNRRDEIKSVFQFNSVL
YADFIRDLNQTVFADKPFTIMGALNVNAQNFDAELAKAKKKEKAGMTCLLTQPVYDQRAA
DNLARAKRELSVDIWAGIMPVVSYRNACFINNELAGIEIPQSVCERFRDADREQAAGLAV
QTALDAAKLVCGVADGYYLITPLKRADIVCEIIKELRK
>A0A1J5HRY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium CG2_30_65_12|TrEMBL
MVAPRISFEFFPPKDIAGAFRLSDTVRDLAPLDPSFVSVTYGAGGTTRALTHDAVTTIHQ
RYGLNMAAHLTCVDASRAETLEIANAYAEAGITEIVALRGDPPKGQGGFVPHPEGFANSI
ELVEALAATDKFNIRVGAYPDPHPEAASDGADVDWLKRKIDAGASSAITQFFFEAETFFR
FRDKAEKAGITAPIIPGILPIENWNGVKKFAAGCGAQIPAWLGETFEKAQRDGREELLSV
ALAAELCSDLIDGGVQDLHFYTLNKPHLTRDVAHALGVTPRAVLQKVA
>A0A0Q6N2C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. Root318D1|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPEFCSVTYGAGGSTHQGTFGAVREILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFLYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDE
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TELCARLRDGGAPALHFYTMNQSTATLAVLERLG
>Q75G11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)|TrEMBL
MAEDKSKFFFVFNNREFMKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLN
PDFVTVTYGAGGSTRDKTVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGIL
NLMALRGDPPKGEGEFKKVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEED
VENLKLKVDAGTDFLVSQLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRS
MAGCEFPSSLIQDLQEVEHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYD
IVRELKGESA
>A0A157ZCE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia calidae|TrEMBL
MKPIELSFEFFPPKTQDGVNKLRASRAELRKLSPKFVSVTFGAGGSTQQGTLDNVLEMAA
DGFEAAPHLSCIGSSKDNLRAILSNYREHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQEHGDWFNIEVAAYPEFHPQSKSPKADLENFARKVKAGANSAITQYFFNADSYFKFVE
EARKLGVDVPIVPGIMPITNFTQLMRFSDMCGAEVPKWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDEGAPGLHFYTLNGSWASKTICERLGFKSL
>A0A429N6K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC00469|TrEMBL
MSVDEKPPTVRAGLTQALRTMGYEVLPFKSTFDKVTSSVPTCVPLSVTASPGKTIGTTVD
LAIALADKGYSVTPHLAARMVTSRTELKEIGARLADSPVTSIFVVGGDAQQAGPYGDALS
LLRDIREGGFEFDAVGIGGYPEGHALIDDGTLSRALAEKAAYADYIVTQICFSPGAISRW
ADALARSGITLPVRVGVPGAVSREKLLRITADIGIGNSARFLRKQRDLLYRFFVPGGYRP
DRIIDGLRRDIDAPTSPLSTFHVFTFNEVEKTEAWRQETLRRLGASGS
>A0A7K6W8Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steatornis caripensis|TrEMBL
MVNETPHTCSATSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPVVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A1E1J8F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania guyanensis|TrEMBL
MSGLISDAIAAEDANKWYTSYEFYPPRSEKAEENFMKVQIPNFMRQSPVFLDLTWGAGGR
TSETTMRLCKDLQNAYPDTPINMHITCTNMSHDLIKETLDFAKEHGIRNILALRGDPPRG
DEFQANPEGFTCARDLVRYIHITYGDYFCVSVAGYPEGHPSRIPEDGTISDEDHQKELEY
LKEKVDAGASVVITQLFYDASLYVKFVKDCREMGITVPIIAGLLPITTYAGFTRMVSLCK
TRVPGDVKKRVEELKENPEALKEYGVEQCVQMIERIRASGLDYHHLHFYTLNSSAQTFQV
LKRLNALVE
>A0A7Y9FGH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas oligotrophica|TrEMBL
MTAVVGVEPLAGNPGAPPVDAAPAGRTRGGRFGALDRPTVSFELFPPRNPDAAPRLWSTV
RELEAAEPDFVSVTYGASGHTRATTRGLVRRLLHESALTPIAHLTCVGTSREEVTAIVEE
FLDEGVRSFLALRGDPPAGQADWQPHPDGLQTAAELVELLREIEHRRCAGSPSQAVRARV
RPLSVAVAAFPRGNAATGGTRAQDVEALLRKQEAGADFAITQVFYEADAYLGLVAEAREA
GVTIPVVPGILPTTDPARLLRVQELTGVPVPRDLLALLDGTDDPAERHRRGIRASIDLVN
GVLDGGAPGVHVYTFNQHGAALDLLDGADLRGRGAEQP
>A0A2H5V890|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon HR04|TrEMBL
MRMKITYEMNPPRIMASLSNSNYNDPNTPKRERFDLQSLSSDLERFYYRVRMLHGLAYMI
HVTDSVLGIPRLSSISIGREIVQKHKLSARCSIRVRDRNTNAILQLVTDAIIAGIDGLLV
IKGDEPRHSSIDSALKPSSVVKFLNEHGFSKHIRLYLSIDAENYSEDELNRKISAEPHGL
ITQSISSLEPLVSLADRVKANNMCIVPCIMVPSPKNKVSASSINLDWSRYEHDVESFVLE
AYSLCGEVMITSPNSFNDGINILKRVMYGKAYQRGTVQRGSDTIGVEYRGKEDENGG
>A0A7W0J119|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MKLTELFEAKKFVLTSEVGPPKGWQTDKMLEEIECVRGKVTALNVTDLQAAAMRLGSLVT
CRILQDKGYEPILQVTTRDRNRISLESELLGAAAFGVKNILCLTGDHPVMGDHPDTMPVF
DLDSVSLLHAASVLMSGKDLAGNELEGDAPDFCLGCVVNPGADPLEPQLLKLEKKIKAGA
RFVQTQAVYEPGKFASFIDRVRKEVGDIPIMAGIVLLKSAGMAKFMNKNVAGVHVPDEFI
EEMTFPKGTPVEEKKAKSVEIGIRLVKELRPLCQGIHFMPLGWDDCVSEIIKQT
>A0A259Y3V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 06-621-2|TrEMBL
MDRLRSDGAARIPFSVEFSPPRDEAGEARLWRAVREFEQLQPAFVSMTYGAGGSTRDRTV
RVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRGISNILVLRGDPPGDPLGDWEK
HPDGVEYADELVTLVRELGDFHVGVASFPEGHYRALNLEQDTQVLVNKLRAGAEYSITQM
FFDVDDYLRLRDRVAAFDPEQGAKPIVPEIMPITSLRTVRRALALSGSALPKALDDRFTA
AAGTGREEDRAAVREVGIELATQIGERLIAEGAPALHFITLNFAKATREVLTNLGLCAAR
V
>A0A176YMY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium neotropicale|TrEMBL
MTEPTTTVQDNGQNGHLAKRPAISFEFFPPKTEEMERNLWETINRLAPLEPKFVSVTYGA
GGSTRERTHATISRILKETSLLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPP
GGIGTPYSTHPDGYQSSPELIAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKAKVD
AGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTSVPDW
LAEKFDGLDDDPDTRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRA
KSAQKAA
>A0A285ZRU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWB16|TrEMBL
MKIIDILKQDKMSLSFEVFPPKKETSFENVKAATEAIAKLNPAFMSVTYGAGGGVSQYTL
EIAKNLKYNFNIPMLAHLTCISSTKETIHQRIEDMKAAGIKNVMALRGDLTPELIANGRG
DCDYHHAVELIRELKAADADFCIGAACYPEKHPESPNQAEDIKHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYATDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFAG
>A0A3S9NMZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter sp. MJ134|TrEMBL
MKVTDHIKKAKGETLFSFEIIPPVKGRNIQELYNNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMREEKYFEATKGGHPYATSLVKQIQDLNCGKYLHEVIETDDCADFCIGVAGYP
EKHLEAPSLKTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVAAAKNMGIDVPIVPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVEDCGTNKEVRQVGIEWAIQQSKELKEAGVPVLHY
YSMGKSDNIKAIAKTIF
>A0A0P0S945|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. EC080619-01|TrEMBL
MVTSVTTTSASTVTERISVDRPFFAVEFFPPKDDQGEADLWRAIRRLEVLDPAYVSVTYG
AGGSSRDRTVRTVERIASDTTLCSMAHLTAVSHSTEELRHVIGSLAAAGVRNIMALRGDP
PGDPLGEWVKHPEGLEYADELVSLIKRSGPFCVGVAAFPYGHPRSADVESDTEKLVGKFR
AGAEFAVTQLFLEPDGFLRLRDRVAAAGFDQPIIPGIMPLTSEKTFHKGPELSGSPLPEA
LVERLSKYSGDAKAFREAGMEVTGELCERLIAEGVSGIHFYSLNRSTATTELVERLGLAA
QPAGADRAESEAVLPV
>A0A0P0SFJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. EC080619-01|TrEMBL
MRQTGEDGRVGDVRLDPCPKRMEFGPCGGVRADLTCELGTVPCPFADGAAVPWTGPPGRS
AAPAAFGHKGPVVLTDLTSPPYDPAALGRIVRTIAGSCDALLIGQHHDEPDFPPTMLAVL
AREAGGHPWVTLTCRDRNRVVLEQDVAGLAAAGAEAVFCVTGDARGPSVRPDVSQVFDLD
GTRLASLAAAAGLPAVVPEAPDAPPTGLRPARLAEKQRAGAGAVVLNHAASPGRVAEFVT
AARGHGATLPVVAGVAVFTDEPGARRLEAFPGLEIDPAAVERVLTASDPVEAGIEAAVDE
AVALLAVDGVAGVNLSGRGSSGDDDTAAAIKAEIGHRIRSRAGTRG
>A0A0T6DRL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter piscatorii|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALSA
RSETEIAPHMSCIGDDKAQIAELLEFYKSLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFEFDVDNLVNKYRAGANASITQFFYNADSYLYLR
DTLEKRGIDTIAQPLVAGIMPITNSSNLIRFADSCGADIPRYVRKRLADFGDDSKSIREF
GFDVVYRLCERLMSEGVPAMHFYSMNKVEPNKRLVEALGLTV
>A0A6N3T396|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter indonesiensis|TrEMBL
MSLSRLSVELIPRTNEALLDDVARVKTLLPAADTLNIPDLMRFPLRSWDAAALVRPHFPS
VVPHVRAIDIAPDATLPGADQDGLKDVLVVHGDPPADLSHRTYPNSTESIIRRYKKEAPH
LRVYAAFDPYRRAPWRELEDVARKKEAGAEGFFTQPVFDLKLFDLCQEWLQNETVFWGLS
PVIGPKSRSYWETTNHVVFPKNFEPTLDANIHFAQTVLRTLSNQKGSVYLMPLRVKLDQY
LPPLLEALE
>A0A3N6QLR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica cretica|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRANGIQNVLALRGDPPHGHDK
FVKVEGGFGCALDLVNHVRGKYGDYFGITVAGYPEAHPDVIGENGLASDEAYQSDLEYLK
RK
>A0A3A3HQR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. DCY119|TrEMBL
MSNYGFSRRSDIGDKIRVSFEFFPPKTDEMEARLWDTVKRLEPLQPNFVSVTYGAGGSTR
ERTGRTIKRILGETSIPAAAHLTCVGASKDEVNAVIAEFVSYGIKRFVALRGDPASGVGG
TYRPHPEGYQNGADLVAGLKSFGDFDISVAAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFASRAGAHVPAWLAERFE
GLDRDPQTHALVAAAVAAEQVLDLVERGVGDFHFYTMNRSDLVVAICHMIGIRAPAVSVV
DTAGSAAA
>A0A0M3GIH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium phaseoli Ch24-10|TrEMBL
MALKNEAQARNIGISFEFFPPKSEEMEGQLWNTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRRAGISIPIVPGIMPIQNLTQLKRFAGACGAVIPGFLDERFAGFDD
KPEERAKVAADVAAEQIENLVRRGIRDFHLYTMNRSPLVSAVLDNLGLSRRPAKNAGAAA
>A0A2A3VMH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium NML93-0792|TrEMBL
MIPISFEFYPPKTDDQRVQLDRTAKKLAAHAPDYVSCTFGAGGSTLSHTPETVRRLKQQH
GFSSAPHLSCVGGSREEIRALLELYRGLGCERIVALRGDLPSGMGRPGDLRYASDLVGFI
RAEFGDAFHIEVGCYPEVHPQADDAHVDMRHFKTKVDAGADAAITQYFYNADAYFHFVDS
ARRAGVDIPIVPGIMPIANFGQLRRFSEACGAEIPRWMQRQMAAHGDDVDAVRELGADIV
ARLCERLIAGGAPALHFYTLNLARPTQTVLARLA
>A0A556MUA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter corticis|TrEMBL
MKITEHIANAKGKPLFSFELLPPIKGQGIQGIYNAIDPLMEFKPPFIDVTSSREEPVYKE
HANGLLEKVSYRKRPGTVALCAAIMNKYGVDAVPHLICGGFTREETEYALIDLQFLGIEN
VLVLRGDARKTESSFVPTPGGHSYATDLLEQVTNMNKGKYLHEDHEAVKSDFCIGVAGYP
EKHFEAPNLKTDFKYLKQKIDNGADFIVTQMFYDNSKYIEFVKNCRDNGINVPIIPGLKP
ITSSKQLINLPKIFHIDIPDALSDAVHACKSEADVKEVGIEWMISQCKELIQAGAPVMHF
YTMGNPGPTKRIAEAIF
>A0A1H1P981|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Friedmanniella luteola|TrEMBL
MAELLATAGRPLFSFELFPPRDEAGSRQLWQTVRELEALGADFVSVTYGASGSTRERTIG
ATEQIALTTTLRTVAHLTCASQSREQLRRVVGAYAAAGVRHVLAIRGDMPGGPREPWVKH
PDGLDNATELVRLVRELGDFCVGVGAFPDPHPSSCDADLDARILVEKARAGASYAITQLF
FRPEDYFALVARVRALGCDLPIIPGIMPITNVRQVARFAELSGAALPEAVVDRVEAVAGD
DDAVRRVGTAIGTELSEALLDGGAPGLHFYTQNRSRATREIYANLASRLLPRRG
>A0A1I4M1Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shimia aestuarii|TrEMBL
MTAPHISFEFFPPQNLEASFRLWDTVQALAPLDPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNATREETLKIADDFAAAGVSEIVALRGDPPKGSAGFEPHPEGFANSV
DLIAALADTGRFTIRVGAYPEKHPEAADQKADIDWLKRKIDAGASEALTQFFFEAETFLR
FRDACAKAGIDAPIVPGILPIENWKGARNFARRCGTDVPAWLDDAFEKAVRDGREDLLAT
AICTELCSDLLDEGVEALHFYTLNRPELTRDVCHALGVVPQVRLENVA
>A0A2W6VJY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
MTAEELAAGAPLYADLPGDIEISFEFFPPKTEKMAETLWNSVQTLAPLKPRFVSVTYGAG
GTTRERTHATVARIVAETDIPAAAHLTCVDASKDEIAAVADAYWEAGVRHIVALRGDPPV
KDGKFQHFVAHPDGYRDAADLVAGLAARHPFELSVGAYPETHPEAASAEADLAHLKRKLD
AGAGRAISQFFFEPEAFFRFRDRAAAAGISADLVPGILPVSSFANVQRMAGQCGTRIPDW
MGRLFEGLDDKPEARQLVAATVAAEMVRRLYAGGVRHFHFYTLNRAELAYAICHLLGVRP
S
>A0A2N6AM38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
QPVFDLDIFHSFMKRIEHLRIPLIAGLWPLASLRNAEFMNNEVPGCHVPDHLMDRMRAHA
DAKEAGRAEGIAIAHETLEQMKESIAGVQISAPFGRIDTVMNILDGVRLR
>A0A2E7Z0H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pelagibacter sp|TrEMBL
MNRNQKEFNIKKLLNNYSIETTPNVYEKYGKFSDLISTDNAVYVTYLPDENSSRVINTAK
KLTNEGFDVIPHLPARTIKDNNELEKYIGDLSEKAGCNKILVIGGGSNQKGNITSSLDIL
KTDLLSKYQFKEVGLAGHPDGNPDISEEELDKAIIEKNEFVKNVDYKAYLATQFFFEVSS
LEIWEQKLNLHNNKLEIHAGIPGPATLKTLIAYAKSCGIGNSIRFLSKQAINITKIMKTR
TPDKLIADLADYKEERPNSKLAKLHFYAFGGIKTTSEWLYDVINSNLEINXKNEFXIIXK
L
>A0A3D0LBQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MIDNALFASRPAFSFEVFPPKKDDGIEKVYDTLDELSDLHPDFISVTYGAGGSENCGKTL
DIAKRIKNVCHVESVIHLPCLHLTKQEAEKMLLEFSDNGIDNLLILRGDKIEGREPS
>A0A1Z5T7B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii EXF-2000|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGVRNILALRGDPPRSDE
YNDPNNPLSEQDDSNRDFTWAVDLVRYIKKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLVEKTAAGADFIMTQLFFDVEAYNNYEKRLRSHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLSRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTL
NLEKVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSS
NRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPINSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSRDDICTIFRRHLKGEIEA
MPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSTDPIYGWGPKNGFVFQKPF
VELFLPSADWQRLKPILQSDDQVTYYAGNAAGEFQSSDENSVNPVTWGTFAGKEIITPTI
IEADSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDA
LIAA
>A0A252AR20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter indonesiensis|TrEMBL
MTDGQSNGLSEKHIDGLLLRNFEAPIPILSFEFVPARTDAMEQRLWHCIRRLAPLAPRFV
SVTYGAGGTTQTGTLSTVLRLKRETDLIPAAHLTCVGATHEDVDDLARCYRDAGVNHIVA
LRGDPPAGAADYSPRPGGYAYASDLVAGLRRIADFDISVAAYPETHPAASSPDADLDNLK
RKLDAGATRAITQYFFDSEIYLRFLDRCLAAGITAPIIPGIMPVSNYEQIVRFSAVCGVT
VPAWLRHLFDGTAENPELRRIIASMVAVEQIRTLQTYGLNEFHVSTLNRSDLTYAIAHIL
GVRPTQTNASRNVTDLLETTEVPDDRETPADFDPTKGTQEGAPPFMLRTLFG
>A0A0Q7EN41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. Root1280|TrEMBL
MSQLSQYFAQNQFCCLVEYLPSMQEVLPVATQLAGFPVCMTLSDRVRSDEDIAPLIAAQS
YPQQIEKVLHYAGKGRDIHDFNLFLTQAKQHGQQNLLLLTGDKLKQHHDGQGSHARTRYL
ESVNAVIAAKQQGGFHIGVALNPFKYSQAEKQAQYLKLHKKLQAGADYIITQLGFDLVAL
KQAHEFLIEENYTQKILACVMPLTLARAKFMLKHNVAGIVITPHMLEVLAQEHDSDQTEN
TYLRCALQILICQHIGYAGVHLSACHKADEQAILTSYIEQYRHLDLKQCEQLWTQLWQLK
TGNELRPAAVEKSKLSNLHQKVKYQFLDTIHSTMFNSSLVKGLGAYIFSANFWNKALAAK
LLLQAEYLSKHFIVGCESCGQCRLAETLYICPETCPKGLANGPCGGTHLDRCEFGDRECI
HSIKARLAEEVDQIQILKKQLIPTVPIEVRGTSSWKNWYVKQ
>A0A2R6APR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marsarchaeota G1 archaeon OSP_C|TrEMBL
MRGSRSEESMKILYEVTPPSKRATRHELDYVVKNASSCGANEVDVTDSPTGESHSSSVAA
CVYIKTKYSLPVMCHIRTRDITLNALRAMVRACAVWEIEHILLVMGEGGENTGLTPTHAL
RVIREEKLLEGSTTKVGFVLQKGKSVEKKIRAKPDFLYTSPLTSVEELEWAVELSRSQNF
ELFPSLIVPSKKNEVILKRIGLQALSAERALTLATHALRLTSNLVVISPADPDEGFSFLK
RLNRNGL
>A0A6G8JG73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mannheimia granulomatis|TrEMBL
MNYATQIDALNQHIADINHKINVSFEFFPPKNEKMETMLWESIDRLSPLKPKFVSVTYGA
NSGERDRTHSIVKSIQDKTGIISAPHLTGIDASPEELKVIAKDYWDSGIRRIVALRGDVP
QGYNKELFYASDLVALLKSVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVAIGIDCEIVPGILPVTNFKQLQKMAKVTNVKIPSWMGKMYEGL
DDDQTTRNLVAASIAMDMVKVLSREGVDDFHFYTLNRSELTYAICHTLGVRP
>A0A703AEU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEAHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2N0LHT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G5|TrEMBL
MKIKDILTKTRPVSFEFFPPRQAEGIPAVLETLDELKQYRPDFASVTYGAGGSTRAFTEE
ITLEIKRNTNVEVMAHLTCVGQNKEELDEVLSRLQEEGVENIIALRGDPPKGTTEFVPVE
GGFKHATDLLHHVVSNYKFGVAAACYPEGHTESVDLDADLRYVKMKVDNGADFLVTQLFY
DNRFYFDFVERARAEGIEVPIIPGVLPVLNSAQVRRFTTLSGSKIPPDLDKLLDKYADSD
HSARDMGVEYATAQVRELWDFGVPGVHFYVLNRSYSVSRILDNLQIAGHQRQD
>A0A842Y0N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon|TrEMBL
MLACTSRNCSRAKRPCREIQGENVNFMETLASGKFIVTAEVSPPKGTDTRQMLKNAALVG
GIADAINVTDNQRAVMRMSPLAACSILKSKGYETIMHVTCRDRNRLSLQSELLGSSSIGI
NNILVMSGDHPVKGDHRGAKPVYDLDSVQLLGLVQQLNSGFDFSGNTLEGKTRILPGAVA
NTELSEAALIKLGKKISSGIRFVQTQAVFDTNSFSGFMEQVNSIRSKYNPDMKIIAGIIP
LKSVKSADFLNSNIAGIRVPQHVIDRMKSAKNPEKEGMEIAAGLIGKLQGMCDGVHIMPI
GNHENTGKILEMAGI
>A0A2S7KAF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinicaulis flavus|TrEMBL
MSQPAFSFEMFPPKSADGAEKVLDAARTLAELGPQFISVTYGAGGSSKDRTLGVVRALSE
EDAAPAAGHITCAGASRAEVDGVLRDYWAAGVRRIVALRGDPEGGMGAQYSPHEEGYPYA
SDLIAGAKKIADFDISVGCYPETHPDARGLQDELETLKHKLDAGADRAITQFFFEPEIFL
RYRDAAADFGIDKPIVPGIMLQSNYQGLTKIARLCGAFVPFKVMRAYETCGEERSARDRA
TVEIAASICERLKREGVEAFHFYTMNRSALASALCQGLGLCKDRRAA
>A0A8J3AHC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gottfriedia solisilvae|TrEMBL
MGLLEKLNNGIVLGDGAMGTLLYSGGLHSCFEELNITERDRIIHIHEQYINAGAEVIQTN
SYGANAGKLRQHGLEKLVKQINQMAVRNAREASKGRALILGGIGGMKYIGSTFATPLERE
IMLLEQASALLEEGVDGIMLETFYDEHELYDAVTLLRERTDIPIIAQVTLQEIGVMQSGQ
YIEKILPKLVDLGADVVGINCHLGPLHMIESLNTVALPKKGFLSAFPNSGLPLYEEGKYV
YKSNPEYFEDMAKPFIEQGVRLIGGCCGTTPAHIAALRNKIDNLEPVTKKEVNNRTITIK
IPKQPEQKNVTLAEKAKQRTTIIAELDPPKTLQTRRFFEGAKALNNAGADAITLADNPLA
SPRISNVAIASMLQRLNIPVLTHLTCRDRNMIGLQSHLMGLSTLGLNEVLAITGDPARVG
DFPGATSVYDVASFELIRMIKEMNEGRLYSGKSLGNGTRFSVAAAFNPNVRKMDAAIKRL
EKKVEAGADYFLTQPVYDLETIDRLYESTRHINQPIFIGIMPLISKKNADFIHYEVPGIT
LTDEVRNRIDINDPLLAIEEGKNIAKEIVDYAIDKFNGIYLITPFLKYEITEELIQYTKT
RKKEEIQL
>A0A7L5DLP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma sp. CJU-R4|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPIKGDTLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAILHRFGVDPVPHVLCGGFSRDETEDFLIDLQYIGID
NVLVLRGDPAKPFSTFKAKENGYSYASELVAQVADMNRGQYLHEEDTAMTPSDFCVGVAA
YPEKHFEALDHDIDFHHLKQKIDKGADYIVTQMFFDNQKYFDFVDRCRQADITVPIIPGL
KPLATRKQLQILPKLFHLEMPADLIKAVEACENDQQARQVGVEWGIQQCRELIAAGAPVM
HFYTMGKADNVMKIAKALF
>A0A158C5L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia glebae|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRASRAELKTLSPKFVSVTFGAGGSTQQGTLDTVLEMAA
EGFEAAPHLSCIGSSRDNLRAILLQYREHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQEHGDWFNIEVAAYPEFHPQSRSPRADLENFARKVKAGANSAITQYFFNADSYFRFVE
EARKLGVDVPIVPGIMPITNFSQLMRFSDMCGAEVPRWIARRLESFGDDRESIRAFGVDV
VTGLCRRLLDEGAPGLHFYTLNGSWASKMVCERLGFKSV
>A0A3D2NS05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionella sp|TrEMBL
MNQSPISFEFFPPQTAEGVEKLTVVRARLATLKPEFFSVTFGAGGSTQERTVDTIRQIHA
EGYQAAPHLSCVGSTRDNIRAMLLAYRQMGIRRIVALRGDLPSGMAGIGEFQYANELVSF
IRAETGEHFHIEVAAYPEFHPQAQSAQADLLNFKRKVEAGADAAITQYFYNADAYFNFVE
AASKLGVTVPIVPGIMPIMRFSQLARFSDACGAEIPRWMRKTMEGYNDDTEAVQAFGLDV
ITALCEKLIAGGAPGLHFYTLNQAAPCLAIIERLGLSK
>A0A1H3A4J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Albimonas donghaensis|TrEMBL
MTDPSGRSLSISFEFFPPATPNGAMRLWRSVERLAPLAPSFVSVTYGAGGTTRDRTRNAI
KAILERARLQVAGHLTCVGATREETLEEADGYRKLGARRVVALRGDPPKGADRFEPHPDG
FRNAAELVTGLRAAGHDRISVAAYPERHPDSADLAEDLDNLKRKLDAGADSALTQFFFDN
DLFLRFRDAAAKAGITAPIHPGILPIENFGKMRRFAAGCGATIPDWLVTAYGNADEQGMT
ETLSRAICAEQCDGLLAEGVEHIHFYTLNNPDLPYDVCRAIGVEPQPLGAAAAGGA
>H2CGK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptonema illini DSM 21528|TrEMBL
MNKILLEVIPREVNTLLNEVSYVKNSYSQISGINIPDLLRFETRSWEAAVAVKSVFSNVI
PHIRAIDFDINNCDPIITFLRENQISSVVVIKGDPPADMSKKVFPTTSIKLIKKLKKEIP
SLKVYAAVDQYRAGIRDEFDYIEMKKDAGADGFLTQPFFDLRLIDIFTEKLHGTEVYIGV
SPVITEKSQSYWESRNRAYFPKDFKLTMDWNTSFAKDVIGYCKKNGLNTYLMPIRIDIEE
YLGSLFGRDTSVIRHV
>A0A2S2G3Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SM18|TrEMBL
MALGTPSTWTDHAPTVRELLATGKTSYSFEFWAPKTAKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTREGTVRATQQIAADSTLTPVAHLTAVDHSVAQLRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSDDWDSDIRHFVD
KCRAGADYAITQMFFHPESYLRMRDRVVAAGCDTPVIPEVMPITSIRQLERFAQLSNASL
PSSLKERLLAAKDDPAAVRSIGIEFATEFCAELVSEGVPGLHFITLNNSTATLEIYENLG
LHRQS
>A0A5C7S918|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera aminoaromatica|TrEMBL
MSTKTPISIEFFPPQTTEGADKLKVVRSKLAVLKPEFFSVTFGAGGSTQERTFEAVSEIQ
HEGHQAAPHLSCIGSTRAHIREILQRYQSSGIRRIVALRGDLPSGVGFAGELRFANELVE
FIRAETGDHFHIEVAAYPEYHPQARSPRDDLLAFKRKVEAGANSAITQYFYNLDAYLHFR
DECTAQGITVPIVPGIMPIVSFSKLARFSDACGAEIPRWMRRKFEAFGDDSDAIKAFGLD
VVSELCERLIAEGAPGLHFYSMNQAGPTLALCQRLGLAA
>A0A846BY33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symploca sp. SIO1B1|TrEMBL
MTKPTHNSFRAAAQSGEFLITAEIAPPKGGNPDHMVKMAQALKGRVHAVNITDGSRAVMR
MSPLAASVILLQYGIEPICQVACRDRNRIGLQGDLLGAQALGIHNILALTGDPVKAGDHP
DAKSVFDLESVRLLKIITQLNQGLAANDKPLTDGATDLFAGAAVDPQLKSWSGLQSRFER
KIEAGAQFFQSQLITDFERLEKFMDKIAAGTDKPILAGIFLLKSAKNAQFINKYVPGVNI
PQAIIEQLANAANPLQEGIKIAAEQVKTAGQICHGVHLMAVKREDLIPQILDLAGIVPLN
EAN
>A0A0J1FF58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium CEB3|TrEMBL
MENRFKASLLDKNRLSVTWELVPGRGAREKAQESALAAAEQAAKGGKVDALTITDNPGGN
PAISADYLGMEILKQGIEPLVHFTCKDKNRNQMESQLYALDRAGVRNLLVMTGDYTVSGF
QGRPKPVFDLDPTHALELITDMNKGLEIPGPKGPSYHQASDFFAGAAVSPFKATEAELMV
QYYKLKKKIASGAQFIVTQLGYDARKFHEVLQFLKVNNLEIPLVGNIYILPFGAARIMNQ
NQLPGCVVTDKLLAELEREKAAEDKGVGARLLRAAKMYAIMKGMGFAGVHIGGHNIKYAQ
VEYVIEQGEELSRNWQDLVHEFDYPMPNGFYYFEKDEKTGLNTDRPVNRQGLPLDAPAGA
AYSMMRLLHAMIFTPGKAFFPVMRKIYAGKSNPRHHFIEHVTKVITNDCKDCGDCALLDM
AYLCPMSQCPKNQRNGACGGSYNGWCEVYPNEKKCVWVRAYARLKKYGQETQIDKNHLPP
ANWDLYQTSSWYNFYTGLDHSAALLGIPKVEKKETRA
>A0A7V6TV17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKIIDIIKSKKPVLGFEIFPPKQNTPIETIYNSLEKFKALNPDYISVTYGAGGSTKRNTI
DVASKIKSEYGIESMAHFTCVCHQEEEIDNLLEIMSEEGLENILALRGDPPRDKPDYDFT
GCAYRYASDLVRHIHSKNKFCIAAAAYTEGHVESARILDDIKHLKIKVDHGVDFLITQLF
FDNRLYFDFVERISDHGISCPVMPGIMPVFAADQIKTMCLRSGCSIPAKLVLLMDKYSGN
PDDMLKAGIEYAAEQISELIENGAPGIHLYTMNRPVSTRKILRAANLLS
>A0A7X8M2X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKIIDMFNKKRPVISFEIFPPRPDVPLDRIYDQLESFEALSPDYISVTYGAGGSRKGRTL
EIASRIKKLHNIESMAHFTCVGHTKEEIDNMLKAMHESGLENILALRGDPPADQPDFDFG
RSAYKYAYELIQHIRRVNDFCVAAAAYVEGHVDSRRLSEDLAHLKEKVDTGVDFLITQLF
FDNRLFFDFIEKARAKGIECPVAAGIMPIFKADQIKSIALKSGCSIPARVVLMMDKYQND
PEDMRKAGIEYASYQIRELIGEGVDGIHLYTMNRPKSTREIMDNISDLL
>D0MDE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10)|TrEMBL
MKVVEILEQATGPLISYEIIPPRRGGSLDEVLAVVEELMPFDPPFIDVTSHAAEVEYEQL
PDGTLRPRVKRKRPGTIGICAAIKSRFGVETVPHLLCRGFTREETEDALIELHYLGIQNV
MALRGDSPNYQKPIPPDRTVNEYAVDLVRQIANMNRGIYLEPLEDAVPTDFCIGVAGYPE
KHFEAPNLTWDIMNLKRKIEAGAHYVTTQMFFDNRHYFRFVERCREVGINVPIIPGLKIL
TSKRHLQLLPSRFHIEIPEELVAEVEAAKLEHVPEIGIAWARRQAEELLEAGVPCIHFYI
MLRADYVREVVAYLRKIA
>A0A1Q7CI79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_2_20CM_2_66_6|TrEMBL
MARIVDLLATGQTFSFEFFPPKDKEEEQLLSRTIADLQPLKPSFVSVTYRGGRISRERTT
RVVVNLLKTTDLTPMPHLTCVAHPRFELGEIIGGFRAAGLENLLALGGDPLPEEESYREL
AYASELVELGRRLGFDSIGVAAHPAGHPRSPDLRSDREHLAFKMKLADFAITQFFFKVEE
YERLRDEMAALGISKPILAGIMPITSLVSVQRMAQLSGYAVPDDVVRRIEAGGDDRAEIR
KRGIEVATELCRDLLAAGVPGLHFYTLNFSKATREIYTNLGLIESRD
>A0A0T9LQ24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia nurmii|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKDIKERTGLDAAPHLTCIDASAGELREIAQDYWRNGIRHIVALRGD
LPEGSGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMTSVFE
GLDNDPETRKMLGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRP
>A0A3N9UQY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
EVGIEVIAHVTCRDRNLLGLQSALMGASLLGIRQVLAVTGAHTRLGEEAGASSVFDLNSF
GLIKLMADLNTGQNALGNPIGGSAGFLIGCAFNPNTPRMEVQVERLEKKVVNGARFAQSQ
PVYDAARLREMMERIAHLGIPVLPGVLPLVSERNCEYLHNEVPGIMIPEQVRRRMRGKEK
DAGVREGLDIAREFIEEVGELVGGFYIIPPFSKYHIAVELLTFIKGKIPGKARQ
>A0A2E9ITI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceicoccaceae bacterium|TrEMBL
MPKLSLQQRLQTGAPLFSIEFFPPKTDASAEQLLRTAEALKLYSPDFASITYGAGGSTRS
RTLKYARHLREDYGYEVMPHLTCVGHSRDELRGIIAEFRAAGLGQIMALRGDPPKGESNF
QPHPDGLHYANELVSLIHESYPECTVGVAGYPEIHPEAPSSEDDLSNLKRKVDSGAHFVT
TQLFFDNNKYFDFVDRARQAQIEIPILPGLMCITSREQALRFCDMCGTTIPAELDEQLSA
AGDDSAAVEAVGTNWVFQQARELLERGAPGIHLYILNRKGPAVELMEKLKEAGFYQG
>A0A1Q4XYX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB03578|TrEMBL
MALGTASTWSDRAHTVRDLLASGSSYSFEFWAPKTEKGERNLWEALRRVEAVAPSFVSVT
YGAGGSTRGGTVRATEQIAADTTLTPVAHLTAVDHSVAELRHVIGQFADAGIRNMLALRG
DPPGDPMAPWVKHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVDK
CRAGADYAITQMFFHPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
DAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A2T6CB46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter mediterraneus|TrEMBL
MRITAMPTPAVSFEVFPPRNVDAAFKLWDTAQALAPLAPRFFSVTYGAGGTTRDLTHDAA
HVLARTSGLPVAGHLTCVGASRADTLAVAKGYAEIGVTDIVALRGDPEGGAETFTPHPDG
FQDSCELITALAETGTFNIRVGAYPDVHPEASDAQANVNWLKRKFEAGADEAITQFFFDA
DSFLRFRDACAKAGIDKPVTPGILPIVNWKSARSFAQRCGTPIPDWLDQAFDAAIRDDRH
DLLATALCTEMCSKLVDEGVDALHFYTLNRPDLTRNVCRALGVMPQIALSDVA
>A0A423GYX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas brassicacearum|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKSAGIKRIVALRGDLPSGMGMASGEMRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>M9M1W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudozyma antarctica (strain T-34)|TrEMBL
MANGIDTPPLPPKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMAD
LGPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPRDKIDTALKEAKEFG
CRNILALRGDPPAGQSEWEPHAAGFTQAQELVEYIRQQYGDYFAIAVAGFPEGHPEAVDG
PEKELERLKSKIDAGADFIFTQMFYDFDIFAKWVKDVRAAGITCPIIPGVMPIQTYGGFQ
RATARFGTLVPQYFHDALDPVKDDDQKVREIGTRLVGDMCKKIVGTGLGISGLHIYTMNL
EKGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRRDEKIRPIFWANRAKSYVNRTETWDEF
PNGRWGDARSPAYGDVDAYGVKLRYSNDEAKEMWGTPQSLDDVKALFQRFCAGQIKALPW
SETPVARETSVISEKLTKMNQLGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEF
FVSPEDLDALIARIEADVQITYHAVNAQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVE
SISFLAWKDEAYEIGRNWAKVYEPSSPSRKFLEAMFDNYFLVNVVHNDFKASDAIFEPFL
SAAKGADVSGALSGLGASVSDAADKVSKAISSLANGGAANGHAATQTPAPAA
>A0A7S7AHE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter piscicola|TrEMBL
MSRLSHYLAQNQFCVLLEYLTSTQEILPVPQQLAGFPVCMTLADRVHSDTDLSPLDAANL
YAKDIEKVLHFAGKGRDISDFENFLTAAKNSGQHNLLLLTGDKLKHHNFGEGQQPRTRYL
ESVNAVMAAKKQGGFLIGVAFNPFKYAEAEQDAQYFKLRKKLTAGADFIITQLGYDIAAL
QQVKSFLTEQHDAQKILACVMPLTLARAHFMVKHQVAGIVITTHMLKVLQEEKTLGLTEP
VYQRCALQILLCQHLGFAGVHLSACHQAEEQLRLQRYIETYRALDFDACLSLWNDLWQVQ
TGKEFHPELRSYSSPISSAQILKYQHLSFIHDAFFESKMAKGVGRFIFKSHFWDQTPMAH
ALLKTEWVSKHAIVGCESCGQCRLGETLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKTELIPTVPLHIRDSSSWKNWFRDI
>U9TH89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus irregularis (strain DAOM 181602 / DAOM 197198 / MUCL 43194)|TrEMBL
MKITDKINNNLETSQPFYSFEYFPPKTDEGLNNLYDRLKRMSHLDPLFASFTWGAGGSTI
DRTTEMCATAQSLYGLESCMHLTCTNVVRGTIEKAMKEAKSAGIQNILALRGDPPRGQEY
WTSCDSDFTHAIDLVRFIRKEYGDYFCIGVAGYPEGNPDSENKEQDLKFLKEKVDAGADF
IITQLFYDVNTFVEWRDECRKNGINVPIIPGIMPIQGYNSFRRITNLCKIHIPAEILNVL
EPIKHDDQAVKDYGVTLAVSMISKLRNEHNTRGFHLCTMNLEKSVRLILEILGFVQTEEE
RNLRRLSRRRSSAGFGPNDIIRQEPDGSLPTAKPVIWKERSVDYLGRPEDWDNFPNGRWG
DARSPAFGELDGYGVSLRIPPEQALGYWQRPMTLDDLKQVFKSYILGEIPALPWYEEPLY
AETEAIRSKLVHLNELGFLTVSSQPAVNGARSDDPIYGWGPRGGYVYQKAFVEFFVRNPW
VTYCASNRNGDFRSNTKDDSPSAVTWGVFPGKEIVQPTIIAKVSFNTWKDEAYALWTEWE
HLYPKDSPSQRLLKDIGDNWWLVNLVYHNYVNSEEIWEIFFKS
>J3UU33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis HD-771|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7W8Z862|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerisporangium krabiense|TrEMBL
MPTVRDLLAAGGRSFSFEFMPPKTDEGERQLWRAIRELEALRPTFVSVTYGAGGSSRDRT
VDAVERIAHETTLTPVAHFTAVNHSVRELRHLIGRFAGAGVRNILAVRGDPPGTDPLAEW
TKHPDGVEYAEDLVRLIRQAGDFCVGVAAFPYRHPRSPSIEADTEYFVRKCRAGADYAIT
QMFFRAEDYLRLRDRVAARGCDTPIIPGIMPVTQMSTIARSEKLSGAPFPPEVAARFERV
ADDPAEVRRVGIEHAAELCQTLLDEGAPGIHFITFNKSSATREVFQALSPEPAVAKAG
>A0A7X5XTH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis italica|TrEMBL
MTSNLNSLAEARRAAASPLFADLAGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIAAESRVPPAAHLTCVEASRAEIDEVARAYWEAGVRHIVA
LRGDVPGGEPYRAHPDGYANAIELVAGLKAIAPFDISVAAYPETHPDATCPQSDLDNLKR
KLDAGATRAITQFFFSPDSFLRFRDAAAAAGIEAPIIPGILPVSNVSQTRRIADMCGTAI
PAWMVSLFDGLDDHPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVSTAKDQAA
>A0A2H9U404|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas cavernicola|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIIPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKPSA
>M4RJL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bibersteinia trehalosi USDA-ARS-USMARC-192|TrEMBL
MSYARTTDLLNQNLAELNGKVNVSFEFFPPKTEKMESLFWDSIQRLATLKPKFISVTYGA
NSGERDRTASLVKKIQQDTGIISAPHLTGIDATPDELRQIAKDYWENGIRSIVALRGDLP
AGYNKAPFYASDLVKLLKEVADFDISVAAYPEVHPEAKSAQSDLIYLKQKVDAGANRAIT
QFFFDIESYLRFRDRCVTTGIDVEIVPGILPILNYRQLEKMAKITNVKIPAWLHHAYQGI
REEDKNTAQIVGANIAMEMVKVLAKEGVKDFHFYTLNRADLSYALCHSLGVRAD
>A0A395ZUV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM43-1|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFNTPSVAHLTCVGRSHADIAAKIDEYRSAGVENILALRGDLPTGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A2I1QDL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNATGVFNHASDL
VSYIRSQRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A291TKZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. CU5|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A2N6RXE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MAYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFSNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VSYIRSKHPDLPILGACYPEKHPEAESLQADIENLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVQRMTSLCSSRITSQVSAMMDRWGSNAECLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A133NPL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLQGLDPDFISVTYGTGKLQDRTATARIANTI
RSEYGIKAVAHLTARYLDYDAVDEALEMFSNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VSYIRSQRPDLPILGACYPEKHPEAESLQADIENLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGIDVPIEAGVMPVANASQVQRMTSLCSSRITSQVSAMMDRWGSNAECLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>C4B1X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia mallei GB8 horse 4|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A2N1QLE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistetes bacterium HGW-Synergistetes-2|TrEMBL
MLIRDLLSRTRPAISFEIFPPKPETPIETVFKTVAGLKELSPNFISVTYGAGGSSRDRTV
EIASAVQNRWGLVSLAHLTCMGSSPAEVEKVMEDLEQEGVCNILAMRGDPRPDGGENHFH
HASDLIRHIRRGHFRDFSLGAAAYPEGHPESPSLEEDLLHLKEKVDAGADFLITQLFFDN
EIFFRFMDRIRALGIAVPVLAGIMPVLNARQIGRIVSLCGASIPPRFARIMSRYEHSPEA
LSEAG
>A0A6G5RCU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces hawaiiensis|TrEMBL
MALGTASVRSDHARTVRDMLAAGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWETDVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLDRIGSLTNAAF
PAALKERILTAKDDPAAVRSIGIEFATEFCAQLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSPQA
>A0A7C2VGG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenobacter sp|TrEMBL
MKIGQYLKEGNFSISFEFFPPKTPEGEEDLFQTIKSLRAINPSFVSVTYGAGGSTRDRTR
RVVERIHKETDLTVMAHLTCIAHSREELLQIIGEYKEIGIENLLALRGDRPANMPDFRPP
EDGCTHADQLVRLIMENYGDWFSIGVASYPEGHPESPNMEWEIKYFKKKVEAGADFSITQ
MFFDNSYYYEFVDLCQKAYIDIPIIPGIMPITNFRQVQKFASMCGATIPQRLIERLEPYA
DSPEETLKIGVEFAIEQCLDLLENNVPGLHFYTLNKSKATLMVYEGIKEALKV
>R6VRX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:91|TrEMBL
MGNTKHTKEQIRERIQQKKILFDGAFGTYYGGKYDTRQLPELANLEAPERVKEIHREYLE
AGAQILRTNTFAANSFCMDIPREQIGETLRSGLRLAREAVAEWRETTGETKEIYIAADIG
QIPGEAMAQKDALSREYEEICNIFLEEGADFFVFETFSEMEELLPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGEAKEIDAVGFNCGVGPSHMHRILQILEKPEGKLLTALP
NAGYPQMVTGRMLFTGDNKDYFVDRMQQMTALGVDMAGGCCGTTPEYIAELAGKLDLTQY
PQAKKDTEPEKKQAPKEDRSFYHTKEAEGRNRKLIAVELAPPMGIDDEKLMDAAHLLQKS
GVDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGI
QNFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFTQAPANYGGAINQSRRNL
EVEIGRVKKKMAAGATFFLTQPISTQESADRVRRIKEETGARILCGIMPFVSLKNATFMK
NEMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVIVMTEDFADGYYFSFPFNRVTMLE
KILN
>A0A369L123|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. DQ26W|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGKFAITSEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGANCHMSSAGVCSLLTRVGYATILQISCRDRNRIAMQGEILGGAAMGAC
NLLCLTGDGVQAGDHPQAKPVFDLDSISLLQIARGMRDEQRFESGRRIETPPRIFLGAAE
NPFVPPLDWRPLRLAKKVAAGAQFIQTQYCFDIERLRNFMLKVNDLGLLEGPDRVFILPG
IGPLASARSARWIREHVPGVHIPDAVIARLEGAENQKEEGKRLCMDLLHEIREIPGVSGA
HIMAYRQEHSVAEIIETTGVLDGRVPWYPGRDDPKELNPESLLR
>A0A2R6FTT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QH_9_66_26|TrEMBL
MSVARSAATVDGATGLLTDLRFELMPFDSFAGQMDHLPDGATIAITTSPQLGLDATIEWA
EKAANRGFEVSPHIAARYVRDEEHLEAIASRLTDAGVTDIFVPGGDREEPAGEFDSAYDL
LTALDDLDYEFEEVGITGYPEGHEFLDEATLAESMERKAPYATYIVTQLCYDPDAVVSWI
EEVRDRGVDLPVEIGIPGVMKYQRLLKISQKVGVGDSVRFLKKTTGILGFVRQLVGSRGK
YTPDDLIDGLAPYADDPHYDIQGLHIYTFNQTSDTESWRYGRLEE
>A0A1I0PJY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter sp. 329MFSha|TrEMBL
MPAISFEFFPPKTDEQRQQLDSAVGRLKGHAPDYVSVTFGAGGSTLSYTDETVRRLRSEH
ALSVAPHLSCMGGTRAEIGALLDAYKASGCRRIVALRGDLPSGMATPGDFRYAAELVAFI
REHSGDHFHIEVAAYPEMHPQAENALADLRHFKAKVDAGADGAITQYFFNADAYFRFVDD
VTKLGVNIPIVPGIMPIANFSQLRRFSDQCGAEIPRWIVKRMQAHGDDAGAVRELGADVV
AELCQRLLDGGAPGLHFYTINRARATTSVLERLAAR
>B1TB42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia ambifaria MEX-5|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRADLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFTQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNAASATRTICERLAL
>A0A163TKZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labrenzia sp. OB1|TrEMBL
MSDQRPSATGRLAASTEMSPRQVVEKTELLAYIPAGTQVYVTDLGNAPEDMIVAAARTLS
ENNLIAVPHMAARRYPSFEAFETRIKRLTREAGVTEVLAIAGEAETPGPLTSSVDLLESG
LFDRLGIRKIAVAGHPEGAPDISPEVIRSFLSRKHEIAANSDAEFRIVTQFGFDPHRVSL
WLDELRAWGNRFPIHVGVAGPAKMTTLLKYAAFAGVENSLNFLKKRGGAVVSMLAGYDPE
TMVDPLETRLISQPECQLAQIHVYPFGGIEKTSNWLCDRKSWSFQTPSSSLTATESA
>A0A0Q8QKR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Root710|TrEMBL
MTTPLIHPGWAQPATNMVTGYSLEMTAKDIGSLRAAAPAIRPTAPVAVTFLPNEDPAARI
AAVKAVRDLGFEPMPHFSARRIGSAGAFEDYLAAAVAEAGVKRCFVIAGDPSTPEGPFTD
SMALIASGAFERHGIAAIGVGGHPEGHPNMSEEQGFAILEAKCAEIVARGMAPLVVTQFA
FDAGRVLSWLAALRARGTDAPVRIGIPGPAGIKTLLRFAARCGVGASTAVLAKYGISVGK
LFGSAGPDRLVDELDRGLGPEHGPVRLHFYPFGGLEKTVAWINGYDRAHRSRAPERTV
>A0A239BJV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Humidesulfovibrio mexicanus|TrEMBL
MQIAELIPTRKPFFSLEFFPPKERETWPRFFAEVEKLKAVNPLFVSVTYGAGGGTQANTL
DVVTHLKRELDLEPMAHLTCVGASSAALRGFLEAISRAGIDNVLALRGDPPKNNPDFRFE
GQEFQHASDLVRFIRTEFPAMGIGVAGIPTMHPESASLDDDLKWVRHKVDAGGQFVVSQL
FFENELFLTYVKRLRERGVTVPVLPGVMPILSMKSAEFIATLNGRAVFGGFYEELERAFA
AGGDEAVRALGLARAVAQVQGLIDAGVPGVHLYTLNRAEACLAIVDKITFP
>A0A0A0DK95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sinensis|TrEMBL
MVRHHTPSLSFEVFPPNPAVGNEKIIQALREMQDIAPHFISVTASNNKFNIEETTVRLAD
FIYNDLKIPTIAHLPAVYLTKEMVSDTLQALDKVGVHNILALRGDIFPDVAPKNDFTYAT
DLIEYIKAEAPHFDIIGACYPEGHPDSPNQISDIQHLKRKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFKAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQPSIELA
>A0A1F4DZJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_62_58|TrEMBL
MLSQKKFPRIFSFEFFPPNTPEGTEKLRATTRQLAQLKPEFFSVTFGAGGSTRDRTLGTV
LDIRAQGYAAAPHISCVASTKESIRDMLQRYKDSGIKHLVALRGDLPSGLAAAGEFRYAN
ELVEFIRKEFGNQFVIEVAAYPEYHPQAKSAQDDLLNFKRKIEAGADSAITQYFYNADSY
YHFVDECEAMGVDIPIVPGIMPIGRFAQLARFSDACGAEIPRWIRKKLEGYGDDTASIRA
LGLDVVTALCDNLLRNGAPGLHFYTLNQAGLTTTIWQRLGL
>A0A254QNN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter sp. 22II1-1F12B|TrEMBL
MTAPTVSFEFFPPQTLAASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRDLTREAVGTLHK
SSGLNVAAHLTCVNATKEETLAIADGFAEAGVSEIVALRGDPPKGTGAFKVHPGGFANSV
ELIEALSARNKFTIRVGAYPDKHPEAADQQADIDWLKAKLDAGADEALTQFFFEAETFLR
FRDACVKAGIDKPIVPGILPIENWKGASKFARACGTVIPEWVEAAFETAIRDGREDLLAT
ALCTELCSDLLEEGVDSLHFYTLNRPELTRDVCHAIGVTPKVVLENVA
>A0A2N2JWR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-15|TrEMBL
MKAGSNLEKVLRAGHFAFTGELGPPRGANVEHVKKKAAFLKGNVDSVNITDNQTAMVRMS
SWAASLLLIQEGLEPNFQMVCRDRNRLAMQSDVLGAYALGIRNMLCLSGDHPKFGDHPTS
KGVFDIDSIQLIDMVKRMRDDGKFLSGGDLDISPKMFIGAAANPFAEPHEWRVFRLAKKI
KAGADFIQTQCIYNMDRFREFMKKAVDMGLHEQCYILAGVTPMKSVGMAQYMAKSVPGMD
VPEALIKRLRDAGKGKAAEEGIKIAVEQIQEFKEMKGVAGVHLMAIEWEHMVPEIAEKAG
VLPRPKV
>A0A0W7XCA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces silvensis|TrEMBL
MTNGKPVFPWGPGPSFSFEFFPPADDKGHRVLWRALREVEALSPAFVSVTYGAGGSSRDG
TIGLSARIAAGTTMRPVTHLAAVGHSKDELRHVLSRLADAGVRDILALRGDPPADPRGPW
TRHPEGVEYAAELVSLIKEWGDFTVGVAAFPERHPRSPDWDSDVRHFVAKCRAGADYAIT
QMFFHVEDYLRLRDRVAAAGCETPIIPEIMPATDVRQISRFAELSNAAFPEDLAHRLEAA
RDDPAEGRRIGVGFATAMAARLLAEGAPGLHYCTLNRPRAALDIHRDVLGSATRAVPSRR
L
>A0A506U8T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Martelella alba|TrEMBL
MSPNATATDDLPRISFEFFPPKNPDAEEQLFKAVKVLAAYQPDFVSVTYGAGASSRTPTF
ATVKRMLAETDLVVASHLTVVKSTRAEVDEVIGQFRDMGVTRFEGLDDDPPGGIGTAYTP
FPGGYANAAALVEGLRGIDDFDISVSAYPEKHPESADRAADIAMLKLKADNGANRALTQF
FFDNDVFENYLNAVRAAGVSIPVVPGIMPIQNIKQLKNFAALCGASIPAAVEARFEGLDD
DPAGRFEVAADIAAEQVLDLKRRGLTDFHFYTMNRSKLMSAVLERIGFAALSAVS
>A0A0A6QK52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio caribbeanicus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDANREELIQIADDYWNNGIQSIVALRGD
IPPGGGKPEMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPSAL
>A0A6A0BAI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus hodotermopsidis|TrEMBL
MKITDIYKEKNAQHQSVISLEIFPPKTNVGVETIYKTVAGLTKKPDFISVTYGAMGSFGR
ENKTLEIAEKIKKDDGIETMHHLTSINNNPEQITEILADIKAKNVKNILALRGDVPANAC
RADFPDVYHYAHELIADIKKAGDFDIGAAIYPEGHVDSPFERENIDHVKAKHDAGANFFV
SQLFFDNDKFLRLNDAVKNAAIEVPIAAGIMPVLQKSQAERMIFFGASLPTRLIKIINKY
KDSPEDLQKAGMAYACQQIDELLSQGVDGVHIYTMNKPFVANGIMAKYL
>A0A410MCY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacillus litoralis|TrEMBL
MNLRDALQQKTLIGDGAMGTLLYSYGIDRCFEDLNLSHSEEVLNVHRAYVNAGADVIQTN
TYGANYIKLTRYGLQNQVKEINTQAVRLAKQAAGPEQYVVGTMGGVRGIQKQAVPLEEIK
RSFREQLYCLLFEEVDGLLLETFYDLEEVTTVLEIVRKETDLPVIAQVSMHEAGVLQDGT
PLTEALELLEKKGADVVGVNCRLGPYHMIQSLEEVPLPDKAVLSAYPNASLPAFQDGRLV
YPTDPSYFQKSAQSLYEQGVHLIGGCCGTTPEHIEAIAARVKGKKPIKEKKVPLKKKTDV
NVAKKEKQTPHLHELARKGRSIIVELDPPKKLNTERFLKGAKALQEAGIDSITLADNSLA
TPRISNSTMASIIKSKYNVDPLVHIACRDRNLIGLQSHLLGLHTLGIHQVLAVTGDPTKI
GDFPGATSVYDLSSFDLIHYIKQLNKGISFSGKPLGENTSFSVAAAFNPNVRNLNRAVGR
MEKKISYGADYFISQPVFNEKQLVEVYEATKHVDAPIYIGIMPLTSVRNAEFLHNEVPGM
TLSADILERMEQAGDNKAQAQAEGISIAKSLIDTAMDLFNGIYLITPFLRYEMTVELTNY
IHEKSASKERKLSDGIHIV
>A0A2S9K8P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malikia granosa|TrEMBL
MGLPLSFEFFPPKTPEGAAKLHVVRQQLYVAKPEFCSVTYGAGGSTQDGTLQTVQAILDE
GQQGASHFTCVGASRESVREKLALFKSMGLRRLVALRGDLPSGYGAMGEFRYAADLVAFI
RAETGDHFHLEVAAYPETHPQAKSPDADLQAYAAKVKAGASSAITQFFFNSDAYFRFVDD
AYKLGAEVPVVPGIMPITNSAGLLRFADSCGAEIPRWIRLRLQAYGDDTESIKAFGLDVV
TDLCDQLRNAGVPGLHFYTMNQSAPVLEILRRLDLG
>A0A147FCS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium testaceum|TrEMBL
MSSLPLIDACPKRMEYGPCGGVGFDGACEIDAAHRCAFLDRPTVPWTGVDRTTPMSPGPR
TAAAADTLTSLDTRPWVVADLPARALSVASIDACAAVLSGEVDAVLAGDAGSARVQFPPA
YRAHLLQRRGLRVWTGLNMRDRNRVAIEGELAALAVEGVAGVHCVTGDHTRTGHRPDAAP
VFDLDSTEATALARAAGHVVSVAGSPAAPPVERRAARLREKLRAGADVCFVNHAGGVEPV
RRFIDEVAEPVRYIPCVPVVVDHASAALLESFTTLVLPDGFLARVRSAREPRAEGIALAV
ALAEEMLALPGVVGVNLSGGREGAEESFAEAMAEVARRLR
>A0A2G9VFC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pediococcus damnosus|TrEMBL
MKLTEIFKHKTVFSFEVFPPHGEAPVDKIRKTLTNLEHIHPDFISVTLGAGGIGAQNQTV
GIANFIQNDLNIPAVAHIPGLYQSKEDVRKLLAELSGHHISNILALRGDKIAGRTPVGDF
NHANELVSFIKEQPGDFQLMGACYPQCHQEAANLTEDIANLKRKVDAGADHLISQLFYEN
QCFYDFMDQTRSAGISVPIEAGIMPVTNKSQIERMAKISGKPLPEKFAAILNHYADNKEA
LRDAGIAYAIDQIVDLVAHGVDGIHLYTMNHSKVAQRIWDATASLFKDSEEKPSVHL
>D8GVK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus var. anthracis (strain CI)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHDAGTTQNGN
DVNEILEQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A286YF17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Homo sapiens|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKANHSG
>A0A3D1Q875|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas sp|TrEMBL
MNSRFAESLLNKNSFCVTWELVPGRGAHEKSQQDAVKAARLAAADGRIHAVTITDNPGGR
PALSASCLGIEIQKLGIEALIHFTCKDKNRNQIESELYALERAGVENLLVMSGDYPSSGF
KGRPKPVFDLDPVQLLDLINSLNNGASEPSAGANPCQPTRFFAGCVVSPFKASEAELMAQ
YYKLKKKIDHGARFVITQLGFDARKFHEALQFVKLYRPELPVIGNIYVLPFGAAKMMNAN
QLPGSVVTDRLLEQIDQERNDEDKGSGARLLRAAKMYAFMKGMGFDGVHLGGHNLKYEQV
AYITEKGEELSSDWMKLIPEFDYPQTGGFYYYEPDHANGLNTKTPVNRTGLVPEYPVSAN
HRLMRWFHQVFFQPGGHLFPLMAKYYKGNKNPEKYRLEHLLKVIGNGCQDCGDCALLDIA
YLCPMAQCPKNQRNGACGGSMNGWCEVYP
>A0A0F2JD81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp. I2|TrEMBL
MVNKFKESILDKNTLSVTWELVPGRGATEKAQESAIASAEQAAKGGRVHALTITDNPGGN
PAILADYLGMEILKMGIEPLVHFTCKDKNRNQMESQLYALDRAKVRNLLVMTGDYTYSGF
KGRPKPVFDLDPSNTLQLITEMNKGLEVPGIKGPIYHAPSDFFAGAAVSPFKSTEAELMV
QYYKLKKKIQGGAQFVVTQLGYDARKCHEVIQFLKVNNLDIPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNEEKSAPDKGVGQRMLRAAKLYAILKGIGCAGVHIGGHNLKYEQ
LEYILDKGEELSPNWQDLVKEFDYPQTNGFYYFEKDEKTGLNTDRPSNRSSRPLDAPAGA
MYSMMRGMHGLLFTPDKKLFPVMRSMYHAAEGKKKTEKRLHAVEHLAKVVMLDCKDCGDC
AMLDLAYLCPMSQCPKNQRNGACGGSLDGWCEVYPKEKKCVWVRAYARLKKYGEEASLDV
PPVPPANWDFYQTSSWSNFFLGKDHSAPILGIKRPESKIKK
>A0A2S9IXX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium phragmitis|TrEMBL
MSHIGASIELAPKQVIESQDLPGLFPTGSRVYITDIGTDTVDTLTAAAKRVSDLGYKPVP
HFACRRLTTRTALETRIRRSAQEAGVTDVLVIGGGLDRPAGDFNSTMQVLETGFFDRYGI
TEMGVAGHPEGSPEFSEAVAMEALRLKKNFGERTGAKLRVVTQFGFDAERFIAWAEGLRE
AGVDLPVHLGVAGPAKITTLIKYAAMCGVGNSITFLKKNAFALTALATTHSPEGVVGPIE
RHVLDNPPSNIKQVHVFPFGGIKKASEWLVERGSWPSSEPSSGNVNASVTAPVAAVQ
>A0A1E4FC12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterium sp. SCN 63-23|TrEMBL
MIDDNLRASRKTADQRPELQLSFEFFPPKTDAMEERFWDSIQKLAPLHPRFVSVTYGAGG
STRERTLRMVSRITSDTGVKAAAHLTCVGASRDEVDDVVRLYACAGVGSIVALRGDPPEG
VGQPFTPHPEGYRNAADLVAGIRRIGDFDISVAAYPEKHPQSADWGEDIDNLKRKLDAGA
SRAITQMFFSNADYLRYVERARKAGITAPIVPGIQPIHSFKQISGFAARCGASIPGWLAE
RFEGLEDDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRANLVLALARLLGRRP
>A0A1M6QEK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWB12|TrEMBL
MKIIDILKQDKMSLSFEVFPPKKETSFENVKAATEAIAKLNPAFMSVTYGAGGGVSQYTL
EIAKNLKYNFNIPMLAHLTCISSTKETIHQRIEDMKAAGIKNVMALRGDLTPELIANGRS
DCDYHHAVELIRELKAADADFCIGAACYPEKHPESPNQAEDIKHLKEKVEAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPDAMKQAGIIYATDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFAG
>A0A139AU08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gonapodya prolifera (strain JEL478)|TrEMBL
MKISKKLEKAFKEDRCFWSFEYFPPKTPQGVMNLYDRLERMYQLGPEFIDVTWGAGGSTS
DVTLEICATAQAVYGLETCMHLTCTNMGRDKVDEALKAAKLAGIQNILALRGDPPRGQLE
WTAVDSGFSNAIDLVKYIRSRYGDYFCIGVAGYPEGHIDNPDKEADFDNFVRKCKAGADY
IVTQLFYDCDVFLEWERKIRAAGVDIPILPGIMPIQSYNGFARMTSLCKTLVPQKIYDDL
EPIKEDDAAVKEYGVQQAIEMCNYLKERGMRGFHFYTLNLEKSVRLILEGLGFVAPVEIA
KPLPWNPSLAEKRKDESVRPIFWKNRARSYILRTESWDDFPNGRWGDSRSPAYGNLDGYG
VSLKYTKKEALEMWKDPTKVSDICDLFARYVSNQLPALPWSDAPLAHESDAIRDKLAQVN
HQGFLTINSQPAVDGVRSDDAMFGWGPRNGYVYQKAYLEFFVCPKVLDALIRRIKNVDGI
TYYAVNKDGDLRTNTISEGANAVTWGVFPGREVLQPTIVESQSFLAWKDEAYDLWLKWRD
IYPKGAEAQRVIQHVYDTWFLVNIVDNDYKRKDGIFELLDGLQCAEQ
>R5U379|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides caccae CAG:21|TrEMBL
MKVIDLINNSKKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEEAPNIESDLYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAERVGIEWCVTQCKELMSHGAPSIHF
YSIGAVDSIKEVAKIIY
>A0A5K7S8A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquipluma nitroreducens|TrEMBL
MKVIDIINQSDKTVFSFELLPPLKGNDASKIYKTVETLVDFDPKYINITTHRDEMMYIEM
PDGRIEKRTVRKRPGTVAIAASIQYKYGIPVIPHILCGGFSKSETEHVLIDLNFMGIKNV
LALRGDGNKGEHVFRPDPNGHSNANQLVEQIVNLRSGKYLEADLKNTAPMDFCIGVAGYP
EKHFEAPNAETDLQYLKQKVDAGADYIVTQMFFDNQKYYDFVDKCRAIGITVPIIPGIKP
INLKNQLTVLPKLFSIDIPQDLAVELGKCKTDDDAKVVGTEWAILQSKDLVAHQAPSLHI
YTYGVSDNTRKIVESVF
>A0A134C8R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonellaceae bacterium DNF00626|TrEMBL
MSTLKNKNAHHQFAITVELDPPKSASSSKTEKDIQKIASVVDAVNIADCPMAKLRMSPIA
LASIIQQRYCVESIFHLTCRDRNIIGLQAELLGAAALGVHNILTLTGDPTDIGDHPHAQG
VFEIDSNGLIEIAHTLNHGYDMNGHELDSSTDFYIGTTANPGADDLDKELKRLESKKLKG
AQFVQTQPIYEIKKAEEFLSGAKEIGLPVLFGIVPLKSIKMALYFNNNVPGVHVPQSILD
IMEKGNRDTGLAIAKDLVNSLRDIHSDGAHIMPVNDIDAVPYIIG
>D0SWS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii SH145|TrEMBL
MNMSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTIND
FNGKGAPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAADL
VRFIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVEKVQAGANAALTQFFFNPDAYFY
FVDRIQKAGIDIPVAPGIMPITNSSNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFG
HEVVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A2S7DLW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas melonis|TrEMBL
MTHLSFEFYPPKTDEQRAQLDRTAARLRGYTPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGNRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGTAFRIEVGAYPETHPQAVDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
AERMGVAIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDAEAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A7C2TVD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MALLDRLRAKADAGEKTFTVEISPPANYKTMVKTDEMVRALKDFDIAGIAVTNSTGGSFR
MNPLAVVETIRAWRPETPIVIHLTARDEGSVRSVYSRADEMNRKAVSDVLVLRGDPTPQR
SREVDAFKFSTVELVRLLREYRDQQGYAIDIFVAGHPEYPSHALSKHMLYQRRKIEAGAQ
GIIANIVTDPTNYVRYVDAALAHGIAVPILPSVIPLTSVRRGLFLQTSLHIPVPRRIMER
LTEAGSKEDAARIGLEITIGIVEHLLREGAPGVNFNLIFPQDIASVADVLRAVRGHATIW
EKYKIEDPEEIEYYNQLRGRLS
>A0A5C1QH55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiospirochaeta perfilievii|TrEMBL
MIKDFIEKNIIISDGAMGTYYSELTKDSVNRVEEANLFNRDLITSIHKEYIESGASLIRT
NTFAANTICLNISREKLKNIIENACLASKDAKGDKNLFIAGNIGPIPEFEDDGSKLLYKD
ILDEYKFIIDCFLNCGVNIFNFETFATDKYLKDVFEYIKLKDKDSFIMVQYSISKSGLTR
VGISIDQLIQDSYPVDVLGFNCGTGPTHLINNIRDKSLKYPLSLYPNAGYPELVNNRTVF
NSDPKYFAKVVLEGVDFGAKIIGGCCGTTPKYIKSINDLLNGNRAETPVVEVKKVETKES
IPNSDKKHIIAVELDPPFKPNLDKLLESARELKDIGVDFITVADSPSGRMRLNSISVAAR
IKRDVNIDVMPHICCRDRNLIALKSDILAAHSEDIRKILVITGDPVPLEERDVVKKVFNC
NSVSLMESISGFNKGVVSDSPFIIGGALNLNSKNLDVQLKKLEDKVEAGATLFLTQPIYD
NRAIEFLSKIKKKPGVKILAGILPLVTYKNAQFLNNEFPGITIPDELIQRFNQDMSREEA
QKIGINISIETVNRLKSFVDGFYFITPFFRTSMIREIISKALMNNR
>A0A6N8X462|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
GNAQGNRRSAGARPGLTARLTQPGPMAAVELRPPRRGLDTARSMDFWIDMYHAVQRFARQ
GTFVLLTDDAAGDAEEESLAHLAANLGDGSDFGTVVPFLTCKHPLEYCRMFARRAAALGT
AGVAVVGGDHSVGPERCVPHGKDLRAVLREDQPGFPLGGWANPHRDPVEQARFVAADDFG
ADFVLTQIVSHHSLGRVARFRAELDRLGVDLPVVYGVFLYRSANPRTLRYLDRYFPVPAR
EVTAEFAAGLSADEICARSVRRLGEAGAEKVYVSNLRSRDAARRLGEVVGG
>A0A2V7SA30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MASFRDLLADGRVHVFDGAMGTMLYTKGFFLNVCYDELNLKQPRLVQEVHAEYVRAGAEI
LETNTFGANPVKLSGWGLADQTEAVNRTAAELARAAAGARASVTGAIGPLGIRIEPFGPT
ARDEAVAYFTRQARGLLDGGVDGFILETFSDLEELHAAYRAVRELCDLPIVAQMTIAEDG
KTSYGTDVEKIARTLTEWGADVVGLNCSVGPAIMLDAIERMAQATDRPLSAQPNAGLPRA
VGDRRIYLSSPDYMANYAQRLIAAGARFVGGCCGTTPQHIREIRACVASMQPRPAVAVKR
DAAAGPAGVEPAPLAARSHWGKKLAAGEFVRSVELLPPKGVQPSKMVEQARALQRAGVDA
VSILDGPRAQSRMGAIPSAIILEREVGIETVIHYTCRDRNMLGMMSDLLGAAAAGLRNIL
IVTGDPPRMGTYPEATAVFDIDSIGLTNVVDRLNRGLDPGGNPIDEPTRYVIGVAVNPGA
SDLERELRRFYWKVDAGAEFAVTQPVFDPGQLEAFLKRAGEFRIPIVAGIWPLLSLRNAE
FLANEVPGVHVPDPILERMREAQAVGDDAALAEGMRIAREVVERVKGLVQGIQVSAPFGR
VDAALQVLG
>A0A561DN53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Brevibacterium] frigoritolerans|TrEMBL
MNFRKELKERMLVGEGAMGTLLYSNGIDQCYEELNCTNPDQIESIHRAYLEAGADILQSN
TYGANFNKLKRYGLEDEVSRINRQGVILAKKAAKGKAYVFGTIGAQRSIRKSDLSMEEIK
RAFREQLYSLLMENPDGILLETFYDLEELETVLQIVKNETGLPIIANVSMHELGNLQNGI
HLNEAFQKLEQLGADVVGVNCRLGPHHMIRALEEVSLPKQASIAIYPNASLPDYVDGRLV
YKAVPEYFGSSALELREQGAAIIGGCCGTTPLHIQAVKHAIGSLAPVKEKFTKSREIEVI
EVNDRELELPLYEKAKTERTILVELDPPKKLGIESFMTGAEVLKKAGVDSITLADNSLAS
PRISNDALANLLKNQLNINPMVHITCRDRNLIGLQSHLMGLQTVGLNEILIITGDPSKIG
DFPGATSVYDLSSFDLISMVKQFNEGLSYSGQSLGQRANFKIAAAFNPNVKYLDKAVLRM
EKKIACGAQSFLTQPIYSVEQIEEVYEATKHLETPIFIGIMPLTSTRNAEFIHNEIPGIK
LPDNVRRAMALAGDDPVKSRIEGVNIARELVDAAREKFKGIYLITPFLRYEMTAELTKYI
RKVDSKQTSEVAVHE
>A0A7G9FWM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium sunii NSJ-8|TrEMBL
MKIRDILSQDTATISFEVFPPKKSTDFENVEKAALGIAALQPAYMSVTYGAGGSTKGHTI
ALASEIQRKHNVPTVAHLTCVCAEKDSIRAALDEMKTAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKENGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITEPIIPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNISEILKA
>A0A2V7NXI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
DGRVHVLDGAMGTMLYGKGFFLNVCYDELNLKQPKLVQEVHEAYVRAGAELIETNTFGAN
PKKLASYGLADDTEKINTAAARLARAAAGDRVSVLGAVGPLGVRIEPFGPTSREEAFTLF
RRQVDGLLAGGVDGFILETFSDLDEIHAALRAVRSACDLPVITQMTIGTDGLTHYGTDPE
TFAKQLAEWGADVIGVNCSVGPAGVLDAVERMVKATDRPISAVPNAGLPKDVGDRKIYLA
SPEYMASYARRMIEAGARLVGGCCGTTPEHIKKIRDYIASVVPRHPTVVVSRAAVAAPAG
VAAVPLAERSNWGRRLACGEFVTSVEIVPPKGVDPTPMLEQCRALKAAGVAAVNVPDGPR
AQSRMGVLPSAILIQRDVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRNILIITGDPPK
MGPYPEATAVFDIDSIGLTNLVYRLNHGLDPGSNPIGAPTRWVIGVGVNPGAIDLDRELS
RFAWKVDAGAEFAVTQPVFDVRQLELFLQRVEQFKIPVVAGIWPLLSLRNAEFLANEVPG
VSVPEEVLARMRKASDRGKEAALAEGVAIAREMFRQVKGAVQGVQVSAPFGRVEVALEVF
A
>A0A7V9AIA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MADFRELLQDGRPHVFDGAMGTMLYARGVYINRSYDELNLREPELVREVHLAYLRAGAEV
LETNSYGANRLKLARYGLEEELRSINARAAEIARSVAGERVCVAGAIGPLGVRIEPYGPT
SAADAQALFREQAEGLLEGGVDLFLFETFSDLLEIQQAILAVRALCGHPIVAQMVMREDG
STPFGTDIALCAERLGEWGADVVGINCSVGPHAMLGAIERMTAATSRPLSFQPNAGLPRE
VDGRKIYMASPEYMAKYAARLIRKGARFVGGCCGTTPEHIAKIAGAVRALVPGSKPVLVQ
TADPATPVREPVPLGERSQWGAKLARGEFLTTVEIVPPRGTDPEAMLEGVQLLKEAGIDG
VNVPDGPRAQSRMGVLATSLLIQNRVGIEPVIHYCCRDRNLLGMLSDLLGAQALGLRNLL
LITGDPPKMGPYPDATAVFDIDAIGLTNLVSRLNRGLDPGGNAIGDPTSFVVGVGVNPGA
TDLEHELRRFYWKVDAGAEYAITQPVFDVAQLVRFIEHIEKEGIRIPIVAGIWPLVSARN
AEFLANEVPGVVVPDEVLDRMRRASALGKEHGVEEGIRIAQEMLTAALPEIQGVQVSAPF
GKVPLALRVFEALPGRTPAGTREAVVA
>A0A8D5Y0I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. (strain Tol 5)|TrEMBL
MSKRIPISFEFFPTKTDAGAEKLKIVHQELQQFNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGDHFKIEVAAYPEMHPQAESYDADIQHFIEKVNAGANAAITQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVIKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A800K4T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
IGPLGVRIEPWGPTARSEAVVFFRRQVAGLLEGGVDGFVLETFSDLSEIACAIGAVRGLT
DLPIIAQMTVGQGGKTAYGNDATQIARELSELAVDVIGLNCSVGPAVMLDALEEMAEVTH
LPLVAQPNAGLPRTVRDRKMYLASPEYMAQYARRMIDAGVRFVGGCCGTTPDHVKHLRNA
VVSMRPKQHAVAGPAAAAGPAPDVEPVPLEARSAWGRKLARGEPVVSVEILPPRGWDRSA
LVEPARRLKVAGVDTLAIVDNPRSLSRMGALAAALIVEREVGIEALVHYTCRDRNMLGMI
SDLLGAAAGGIRNVMAVSGDPPSQGPYPDATEVFDIDSIGLTNVLNGLNRGVDPGGSSIG
PPTEFVQGVAVNPGAVDQEREVERYRYKVEAGADFVVTQPVFDPEALERFLERTRDVRVP
IIAGIWPFLNVRNAEFLSNEVPGVVVPDTFVERMRVAETGGPDAALEEGVLIALEMIEAV
RPHVQGFHLSAPSRRVDVALRVLREARVSATA
>A0A2E9WXC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MDGAMGTELYASGVFVNVSYDGLNLETPDVVETVHRNYVNAGAEVIETNTFGANPVKLSS
YSLADRTEEINHAAVXLARRSAQGRXXVVGAIGPXGIRIEPLGPTSREEAQEFYKRQVDG
LVEGGVDGFVLETFSDLNEMEQAFKAVRSRSPLPVICQXTVGDDACTSYGTSPEDVATEV
ASWGASVIGLNCSVGPAVMLEAVERMAEVTDLPLSAQPNAGLPRAVGDRKIYLAXPKYMA
QYARRMIEAGARFVGGCCGTSPEHIRSIRALVGGVRPPSTRARPGSHAESHDTPIQPEVP
LGERSVWGRQIAEGTFVTSVEVTPPKGWNAEILLGQCRRIQAXEANTVNVLDHPHAHTRM
SALPAAMLIEREVXIETIVHYPCRDRNMTRMISDLLGAAAAGLHNLLLVTGRPPAMGPYP
DSTASLDIDSIGLTNVVHGLNRGVDPGGNAIGVPTRFVIGVRVSQVAVDQDREAGRLNWK
VDAGADFVITRPVFDAEXLHSFLXRVPELSVPIIASLRPLTSLRXAEFLHNEIPGIQIPD
RVLARIANAEAHGEXAARXEGXSIAMXXFXAVRDSIAGVXIHVADGNLDGALELLSEIRD
SA
>A0A3M2GBI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MADSFLEALEKSILIADGGMGTMLYSRGIFINRSFDELNVSMPGLVREIHREYIQAGADI
IETNTFAANSFKLEPHGLEGKVYEINLEGAHLARKEAEKAHRRVFVAGAMGPLKLPPEPF
GHISPEDVRRSFREQAEGLIDGGVDLFVLESFSSLNEIHQAIIAIREASEHLGYTPPIIA
QMTFGDDGNTLYGAKPEKVARVLEGWEVDVIGANCSIGPQPMLDSISAMATVTNRPLSAM
PNAGLPKLVDERYIYMTSPEYLGKYAKRFIKAGCRIVGGCCGTTPEHIKAVATELAALRP
AVSRLFHIPKPEHITVEDTQPVVEPVPKAQKSELARKLSEGKFVSSVELLPPRGTNYDRV
IKAATRLKEHGVDCINIPDGARAVARMSPQAMALLIRQQVEIEPIIHYCCRDRNLLGMQS
DLIGAHALNIRNILVITGDPPKMGDYPDATAVYDVDSIGLTRIITNLNHGCDLVGNPVGE
PTAIHVGVGANPGAINFEEEVRRFELKAEAGAEYAMTQPVFDVRILEKFIKRVEHLNIPI
LVGILPLTSYKRAEFFHNEVPGMSVPENIREKLAAAKREKEAKEIGIQLAQEALLAAKPM
VQGVYVMPVAGGSRLAVRVLEVLT
>A0A2V7KRX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYGKGFFLNVCYDELNLKQPRLVQEVHAEYVRAGAEILETNTFGANPLKLNSYGLA
DETEKINRTAAELARAAAGGKASVVGAIGPLGIRIEPFGPTSTLEAQALFARQVQGLLGG
GVDGFILETFSDMDEMHAALLAVRAASDLPVVCQMTVGTDGLTYYGTDPDTFTKQLAAWG
ADVIGVNCSVGPAGVLEAVEKMVKATEKPVSGQPNAGLPKDVGDRKIYLASPEYMASYAR
RMIEAGARFVGGCCGSTPEHIKKIRDYVASVVPRQPSVVVSRAQVQAPAGVSPTPLAEKS
RWGAKLARGELVTSVEIVPPKGVDPKPMLEQVRALKAAGVDAVNVPDGPRAQSRMGVLPS
ALLIEREVGMETVIHYCCRDRNLLGMLSDIIGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLTNLVYRLNQGLDPGNNPLGGATRWAIGVGVNPGASDLDRELSRFAWKVDAGA
EFAVTQPVFDVRQLEAFLKRVEQFKTPIVAGIWPLISLRNAEFLANEVPGVSVPEDVLQR
MRKAQERGKEAMLAEGVTIAREMFTRVKQMVQGVQVSAPFGRVEVALQVFT
>A0A7X4FIM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MRFLDYFTGNQPVISFEIYPPQTQGGMRALKARVIPNLLKLNPSYMTVTYGAGGSTRAKT
LEIASLIQNEFGLTAACHLTCVGSSRTDIDDILKAIRTEGIRNIVALRGDPPRGEDTFVP
AKDGFAYGNELVAHIRSTEPKDDGFGLAVAGYPEKHLEAPDFDTDIENLKRKVESGGDII
ITQLFYNNEYFFRFVDRVRAANITAPVVPGLMPILAAGQIQRIASLCGSEIPEDLQDQLK
GAVDDEDKAMRIGIDQCIGQATELLEQGVPGIHFYVLNKSTHMRRIISALPL
>A0A6A0B542|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus insecticola|TrEMBL
MKITDIYKEKNKANKSVVSLEIFPPKTDAGIETIYNTVAGLTRKPDFISVTYGAMGSYGR
ENKTLEIAEKIKKEYAIETMHHLTSINNNPEQITEILQEIKSKNVENILALRGDVPVGAH
REDFPDAYHYAYELISDIKKAGDFDVAAAIYPEGHVDSPLEVENIEHVKRKYDAGANFFV
SQLFFDNDKFLRLNDYVKNSGIKAPIAAGIMPVLQKSQAERMIFFGASLPTRLIKIINKY
KESPDDLRKAGMDYAFEQIDDLLSRGVDGVHIYTMNKPFVANQMMDKYL
>A0A7V4NM00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MPPRLPALPDDRPFRVSFEFFPPKTPEMEEGLWRAITRLAPLAPQFVSVTYGAGGGTRER
THRTVKRLLEETALQPAAHLTCVGATREEVDAVARDYWAAGVRHLVALRGDPPAGEGPYV
PHPGGYAYAADLVAGLRRVAPFELTVAAYPEVHPQATSAAADLDNLKRKVDAGATRAITQ
FFFYNDVYFRFLDRAAAAGIGIPIIPGIMPVTNFAQMTRFAAACGAMVPRAMGRLFEGLD
ADPETRKLVAATICAEQCLRLADQGVREFHFYTLNRADLSYAICHVLGLRPAAEGARA
>A0A1F4GM79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium GWA2_64_37|TrEMBL
MIAANAQGTGFPVSFEFFPPKTPEGADKLRAARQQLYALRPDFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPEADLNAYIAKVQAGADSAITQYFYNSD
AYFRFVEDTQRLGANVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A1S1H2C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC34B10|TrEMBL
MSRQTPSLSFEVFPPNPAVGNEKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETISDLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPNFDIIGACYPEGHPDSPNQISDIQNLKRKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDSESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAQYIHQATHALFNHQSLG
>A0A3A5JJ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buttiauxella izardii|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATREELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNYKQAHKFATMTNVRVPHWMAQMFE
GLDNDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A3D2SYH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
RPVMVRVTDVDQEGSEILDPVPLEACSTWGRKLSRGEPVVSIEVLPPRGWDRNAIVGPAH
ELKDAGVDSLAIVDGPRSRSRMGALSAAVIVEQEVGIEAMVHYTCRDRNMLGMISDLLGA
AAAGIRNLLVVSGDPSV
>F4TMY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli M718|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2S7A7T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. guizotiae|TrEMBL
MTPLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWISKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A2E8WAH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MRFRDYFKDPAQQIISFELYPPKTAKGMLTLKEQVIPNLVKLGPSYITVTYGAGGSTQGM
TLEIASTIRNQFDLESACHLTCVGASKADIEQIVRKISAEGIENIVALRGDTPKGQDRFT
THEDGFGHANELVSHIRSMEGIGEGTGLAVAGYPEKHQEAPSLDEDIENLKRKVDAGADV
IITQLFYDNDTFYAYRDKVAAAGIDVPLVPGLMPIQSSHQIQRIASLCGAHLPDPLLEKL
EDAGEDDKLATEIGTEQCIEQSNALLASGVTGIHYYVLNRSSQIHRVIRGIDRQNR
>A0A2M7VR80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium CG_4_10_14_0_2_um_filter_35_18|TrEMBL
MKVTEHIAKANGKTLFSFEIIPPKKGHNIQQLYDNIDPLMEFKPPFIDVTTSREEYIYIE
RNGLLDRKVTRMRPGTVGICASLRYKYNVDTIPHILCGGFSKEETEYVLVDCQYLGIDNL
MALRGDAMKHQRFFEPTKGGHEYAVDLVKQIGDLNKGIYLHDLMETPTKADFCIGVAGYP
EKHMESPSLPSDLKRLKEKVDAGANYVVTQMFFDNQKYFKFVKAAREMGITVPIIPGIKP
LAVSKHLQILPHVFSLDIPQELIDSVSHCKDDKAVRALGIEWAIHQTKELLKAKVPVIHY
YSMGKSDNIKSIAKQFF
>A0A366X976|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter gallaeciensis|TrEMBL
MTTPEISFEFFPPQNLAASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRDLTRDAVSTLHS
SSGLNVAAHLTCVQATKEETLSIARDFAKAGVKDIVALRGDPPKNAGQFHPHPQGFANSV
ELIEALANTGEFNIRVGAYPDIHPEAADGRADVDWLKAKLDAGASEALTQFFFEAETFFR
FRDACEKAGIDAPITPGILPIENWKGARNFAKRCGTAIPAWVEDAFEKATRDGREDLLAT
AMCTELCSDLIDGGVDKLHFYTLNRPELTRDVCHALGVTPKVDLQNVA
>A0A2W4SH02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MTLYDLLTDDRPHLFDGAMGTMLYQKGIFINRCYDELNLREPELVSDVHRSYVKAGAELI
ETNTFGANRFKLAQFGLEERVREINARAAEIAREAAGGRALVGGAIGPLGIRIEPYGPTS
LEEARAAFREQAEGLAEGGVDFFVLETFSDLMEVHQALLAVREVGDFPVIAQMTVQETGA
TAYGTPPEVCAARLDEWGADAIGLNCSVGPHGILTAIEAMASATQKRLSAQPNAGLPREV
HGRQIYMASPDYFGKYAQRLIRAGAKFIGGCCGTTPEHIRRMADALHAIAPRRVIVHVTT
PEPETTPPAQTKPLAERSNWGRKLAAGELVTSVEIVPPRGTNPAKMLAGVRLLKRAGVDA
VNVPDGPRAQMRMGALATSVLIEQKVGIEAVVHYSCRDRNLLGMLSDLLGAHALGLRNLL
LITGDPPKMGPYPEATAVFDIDSIGLTNLVRRLNQGLDPGGNAIGEPTSFVIGVGANPAS
SDRDYELNRFYWKVEAGAEFAITQPVFDPEQLLAFIEELKTRGIWIPIVAGIWPLVSARN
AEFLANEVPGVVVPREIVERMRRASEKGKDAALEEGILIAREMFERVRAHVQGIQVSAPF
GRIPLALRVFEGIPGIDAAVAQGGEEEESAADAGFVPPGTTSPGTHAAGRR
>A0A6L9MGD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantimonas aggregata|TrEMBL
MSLSLPQTRDVIDASIEVAPKQAMRSTDLPGLFPAGTRVYLTDVGIDSVRDFVAATRRIA
DLGYVPVPHIPARRIRSREELLTRIRAYAEEAGVTDVLVIGGGLDRPAGPYTSSMEILES
GLLDRHGISEIGVAGHPEGSPEFSLATAEAALRLKRDFCERTGARMRIVTQFGFDADVYI
DWAMAVRDSGIGLPIHIGVAGPASITTLIRYAALCGVGSSVTFLKKRTGALAALAAHHSP
ESVVGPIEQHWRQTPESPVRQIHVFPFGGLAQSAAWLRERGSWPGSAAERALG
>A0A7V3HMM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MEFLGLEAPLIADGGVGEYLYSLGFPREYLASEATVRNPDLVARIHAEYVSAGAQLVTTN
TFDANVEKLDKHGLAHRCREINALSARLARESGAPRVAGSVGPPDPGLSYSFAPRDPSRL
DEFYLPQIEGLLEGGVDLILLETQVDPKHAQYLFGLVRSLSSDVPVAVSFTFGADLLTPA
GFSIEDIVAQMSGIPLACLGANHGVSPLQFLDIYKHLLALSPFPIILEPNSGLARFHDGS
FVYPSNPAHFARCMASCAGPKTAVLGGCCGTTPEFIRALKDLLSSRNVEPLTLEWASEDS
PIPSAAIASPPRLAEAISERNALIVEILPPKDADPSSFLEKAEDIKRYAPVAVSVPDSPM
GRVRVSPSLMGMLLRERAGIEPLIHFALRDRGLTRVQSDLLGLSAAGLHAIFIIAGDPPE
LGDYPHASVIHDLSTEDTLSLIANLSVGKDLVGRSIGRGAYFFPGTALSFADPKAKEKLV
RRWELGSRFFITQPVYSAEDLESWVYQLEEYPVIVSLMPMRSKANALYLASEVPGIRVPE
DVLKKVESLEDRDVLAFSVEILSKIMEALKGIASGIYISGPARGVEELTRVWRGL
>A0A520VTH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MRIKDKIKRPRRPVVAYEILPPREKDGTLNSYAAKISSLLSQTHIDAINIPEVRDEAARG
ERPVKNQLRAEPREFGRLLQDIVGVEAIVNRVVVHQKLNEELKWLEETNKKYEIENLIIV
GGESRSIDYPGPSVNEALAAIKKNENINLLCGGISIPSREEESLKLVEKSENGCEFFTTQ
VLYDSSKIIKMISHYQKRCDEKKTFPRRLLLSFAPVSSEKNIKFLKWLGVEIPVEIEKLL
IEDLSKMTEKSMEIAVNVLQETLNHLNENNIIVPIGLNVEHIMSYNFQASIEMLQELSRI
YREFCIKTDIY
>A0A8J2ZVW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pullulanibacillus pueri|TrEMBL
MSKERRTQFLEQLKTDYIIGDGAMATLLHQSGVPARTCFEALVLNQPELVQEAHMAYLSA
GATLIQTNTFSGHRMGLGRYGLEDRVWEINHSAVKAARQAIQLHQDHLQINNVTHSEAFV
FGTIGSTADIKVPNFNSQGARMSLKFLFEEQLTALLEASVDGLLLETFSDLTELQLAVET
ARQFTNLPIIANLSPEAIGVTRDGFPIDEAFSILEDAGADVVGLNCRLGLSGILRSYESL
ELNPHSHYAAVPNGGLLHMVDGEYSYTGNANYFAKIGLQLVQKGVKFIGGCCGTTPDHIR
ALAKQLKDFSHSKATAEPTLSHVSIQKPIQVRSRTLEPKMPTDKWDQESLNVIPQQSLVQ
KAKHEPTIIVELDPPKVLDVTKYINAAEKLHQAGADAITIADNSLGTVRVSNMAIASQLK
NRGIEPLVHIACRDRNLIGQQSHLMGLHVLGIHHILLVTGDPSRFGDLPGATSVYDMSST
DLSKMVKKLNHGVAFSGQPLKQSATFVIGTSFNPHVRNFNKAIDRLKRKLDAGADYVMTQ
PIFDIQLFEKLARAVEPFNVPVFVGIMPLTSSRNAQFLHNEVPGIQIPDSILERMDKDSN
KEAALEGLSISETLINEALNYFNGIYLVTPFLRYDLTSHLTRYIHGLKKTVKG
>A0A7Y5JND0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MSQRRSQEVLDRLRSEVMIVDGAIGTALYSQGFSHRTCFDELNETHPRIVEDLHRSYIAA
GAQIIETNTFGANPFRLLDHGFAEKTKLLNRLGAEHARRAAGDSVYVAGSIGPLDRVLEP
IGPITLAQARSAFKEQVEGLLEGGIDLFIIETISNLLEMREAIAAVRELSDLPVVATMTF
TEDGKTLVGDKPAQVVRALIEYGADVVGANCSVGPQAMLEVLERMSGSTVPLCAQPNAGN
ARVVGGRFIYLASPQYFAEYAVKFADAGVALIGGCCGTTPEHIKAVADAVKGRQPGKTPF
VVGADIDEDGKVEGPHRGLPFSEFRANLGKTFQISVEIDPPRSYDPGPFIRHAQRLKAAG
VDLINVADSPLARARMSAVSMAHLIRRDAGVDVLLHVSCRDRNAIGLQSELLGAHTLGVL
NILAVTGDPTSVGDYPFAKGVFELDSIGLSRMVTQLNKGRDLTGRDLDEPTHFLLGVAVN
PTSPNLDLEYDRFKQKLDAGAQFAFTQPLFDPHTLDEFLNRISAFSNIPIFVGIMPLRSS
KHAEFIHNEIPDMFVPQGIRDRMKSAGTEGAKVGVEIAQKFLLDTKEMVQGCYLMPPFNK
FDMAIEVMKVLDRESISN
>A0A7X2NFN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoramibacter porci|TrEMBL
MKLSEQLKIDRPMLSFEVFPPKTEARFEPIMEAVKGIAKLNPAYMSVTYGAGGGTSQYTV
DIAKKIKAMNVTPLAHLTCVSSDQATIHSQLSALKAAGIENILALRGDLPKDYVPGEYRH
ASELIDEIHHFDADFCIGGACYPEGHPESARQKDDIGHLKEKVDRGCEFLTTQMFFDNDL
FYNFMYKIREAGINVPIVAGIMPVTNAAQISRIVDLSGAFMPQSFLNIVDHFRDDPASIY
EAGIAYATEQIVDLFANGINHVHVYSMNKPDVAAAIQNNLKSILKK
>A0A846S150|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter pigmenti|TrEMBL
MNTSTELPVRIEIIPGSNIVARLRQCVPDDSTITVTCLPHHGPAETVRQSVELAERGYRA
VPHLAARSIESRQQLREFTQRLSEAGVKDIFVIAGDARTPVGPYAWSLPLMEEIAGLGLF
ELGVAAYPEGHPSVQEPELTQLLLKKQELAGWAVTQMCFSGPVLGEYLDRLRSDGVTLPV
WAGIPGRVRRTRLVSLAGRIGVGPSLKFAQRSGSLLRNVLAPSSYNPARLVRSIDEGGGF
AGLHVYSFNDVERLGV
>A0A523ARI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hadesarchaea archaeon|TrEMBL
MKPFSHLMKAISEGKFVYTGELEPHRSLDLSEVESWARTLKEAGILAANVTDNPRSDSAI
SSLVASYLIQRNTGLETIYQLRTADRNRLALLSDVLGAAALGLKNILALTGDHTRTGTTP
SSKPVFDLDSTGLIALIHRMVHEGKDLDGNEIKGPRPEINVGGAANPNMDPLEIEVLKLE
RKAEAGAEFFQTQVVFDVEVARRFLREIEHLKVPTLIGIFPPRSYGQAEFFDKYVPGVRV
PRPFMEAFARFKEIGDKQKRSEKINEYNVEYFSSFIREVKREKACAGIHIMAVGYPEVIR
PLMESVK
>A0A7Z0N094|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MSQKKAISLEFFPPRDIAAQEKLVRSAKQLLALHPSYVSVTFGAGGSTRSGTAETVRLLQ
NLGCDAAPHLSCIGSTRAVLADILDTYRQQGIRRIVALRGDLPSGMGGDQGELHYASDLV
AFIRQHSGDWFHIEVAGYPEMHPQASSAEADLEHFGNKVKAGANSAITQYFFNADAYFDF
VGRVRAKGIDIPIVPGIMPITNYAQLARFSNMCGAEIPRWLRLRLVDYGDDKASIRAFGV
DVITKLSQDLLDNGAPGLHFYTLNNAEATMAVGQQLRLD
>A0A661B2H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MIENIFEYIKEHILVADGAMGTELYTRGVPRGHCYDELNLSRPDIVERVHRDYIAAGAKM
IETNTFGANRHILGTYYDLAEKTFAINEKGARIARAATLGKDILVAGSVGPITRPFETEN
RPGVSELNGIFSEQIDALIEGGVDLIILETFADIEEILIALHAVKRNKPGIPVICSMSFV
EGGRTITGIDPQTAAEKLLSQRVKIIGANCGTGPRGLLEALKSLAISKDTILSAMPNAGL
PTFTDGRFEYTAEPDYLAYYAKKYAMAGVAIIGGCCGTGPEHTKAIAEAVGNLKPKPPKK
IAVGVIKEPGEAPIREREKTSFEKKIEKRFVYSMEIDPPRGTGTAETIEAARRFRELGGD
AINVSDIPMARLRMAALPLASAIRCGADIDVVLHATARDRNLIAIQSDLLGAHALGIDNI
LALRGDPPSVGDYPYATGVYDVTSPGIVSILSAFSQGYDRLGVEIDNPADFFIGVALNQN
ATHWEREVAHLDDKINAGAKFIQTQPVFDIKKLETVIKAVDGRAKIIASLLILASERHTE
FLHNEVPGISIPKSIREAMRGLSGAKGRERGLEIARETLDALREKADGVCLMPPFGRYKL
AEELIS
>A0A6L9MCS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantimonas aggregata|TrEMBL
MSRTSPLSPSGINVSFEFFPPKSEKMEENLWRSIERLAPLGPRFVSVTYGAGGSTRERTH
STIERILKETSLTPAAHLTCVDASREDVDAVVRQYWETGVRHFVALRGDSQAGVGGEYVA
RPDGYRNAVELVAGLKAFADFEISVSAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNDVYERFVERVRKAGIYIPIVPGIAPIHDFTKIARFSSACGTKIPSWLAERFDGLEN
DEQTRSHVAAAVCAEQVLDLTSRGISDFHFYTMNRADLVYSICHILGLRAGTAGGAQAEG
KAEAA
>A0A2E0D5W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MINSNLYKNTFKTSFEVVPPKYEINNIFLKKLVRHSNKFDLLDLTCCPMANLRITPISLA
HSLISQGISPKKIIINFSTRDRNTLALQSEILGALAMKIDKILVVKGDRIIKGNSKKSKE
VFEINTGKLIKILSDLRQGYDYSKNRTNTSLNYEIFSTLNLNKSYKELIRIINQRLKQGS
NFFITQPIFSEKDFELMSKLSLKTDYKILCGILPITNIKVLHNVLKKLGGIDVESEHLKK
IQKMDENDIFNHSKEYLKNLIKVYKEHLDGIHIMTSGDISKALKLIENL
>A0A533SEJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
RTMRDEGKFLGGEEIKGKPMLFIGAAENPFADPFEIRAARLGKKVRAGVEFIQTQCIYNV
ERFERWMGMVRDRGLHERCAILAGVTPFKSVGMARYMKNSVPGMDVPDEMIERMKGVPKE
KQSEEGIKICVETIQRLREVPGVRGIHIMAIEWEEKVVEIAKAAGLLPRPQPT
>G0VCN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naumovozyma castellii (strain ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC 1992 / NRRL Y-12630)|TrEMBL
MSIRQIYATRNEPSVSLEFFPPKTESGTRNLMERMGRMSALDPLFITVTWGAGGTTADKT
MELAVLASKELHLPVCLHLTCTNMERHIIDDALEKCLNNGIQNILALRGDPPVGEDWTEN
DADTGSGFNHAVDLVKYIRQQYGDRFCIGVAAYPEGHYQSDVDGVVQDPIRDLAYLKEKV
EAGADFVITQLFYDVEKFIKFEQMFRDIISNDLPLIPGLMPINSYSLFQRAAKLSHASIP
QQILNKFPLEIQADDHMVKSIGVEIIIDIIEEIYRRTSGRVKCFHFYTLNLEKAIAQIVS
QSPLLSHILEETESKENNDAAFVTPQDNELIEPDEDGDIVLDDADMDDFHEGKKRRRHSS
NVSAEFMLNRALVTQRGSSGLSDRLLDQNNSGNMPSKKFVISISKGSGALGRDATWDEFP
NGRFGDSRSPAYGEIDGYGPTIKVSSKKAYELWGQPTSMKDLKSIFIKYLEGSIDALPWC
DLGLSAETGLIQEELIQLNYRGYLTLASQPSTNGSSSTDKIFGWGPKKGLVYQKAFVEMF
IPKQQWENVLKPKIKQYGIGKFSYYAGDATGTFDTNLEPKSSNVVTWGVFPNSQVIQTTI
IEEESFKAWRDEAFSIWSEWAKLFPRNTPTNLFLRQVYSDYCLVSIVHHDFVEPDELWEV
LFD
>A0A0B4CYM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tateyamaria sp. ANG-S1|TrEMBL
MPTPDVALSFETFPPKSLDASFHLWDTVQALAPLNPRFVSVTYGAGGTTQSLTQEAAQTL
RKTSGLPVAAHLTCTGQSRDDVLATAQRYAKSGVKDIVALRGDAPGGGAFEAHPDGFANS
IDLIRALADLNQFTIRVGAYPDSHPDAASPQQNIDWLKAKLDAGASEAITQFFFEPDSFL
RFRDACAAAGITAPITPGIFPVANWARARKFAETCGTPIPAATSTAFDRAEREDRAHLFA
LTHCADLCDTLISEGVDKLHFYTLNRPDLTLKVCRALGLVRPTQMRNVA
>A0A0N0Z947|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moellerella wisconsensis ATCC 35017|TrEMBL
MSFFHANQREALNQSLAELDGQINVSFEFFPPRTEEMELTLWKSIDRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKDRTGLIAAPHLTCIDASQDELREIARDYWKNGIRHIVALRGD
LPDNSQRPNLYAANLVELLKSEADFDISVAAYPEVHPEAKSAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLDKFSKITNVRIPTWMRKMYE
GLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPE
>A0A522UAW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MRIAEMLARSRPSISFEFMAPRDETEVDILERTIAALAGHAPDWVSVTYRLRTGEKTLEL
VTRIKRQYHIEAMAHLTCANSVDRTRRVLNWMEKEGVANVLALRGDAQSPDQPFKAADPQ
LTHGSDLVAFVRGNGYRFGIGAACSAEKHPESPDLEHEFRYLKLKVESGADFLITQLFFD
NRFYFDLVARARAAGITVPIVPGLMPVPSRRSLAFMTAMSGATVPPALQAEIDAQPDDDA
IRLVGVRHCIAQCVELLEAGVPGLHFYTFNRARGPMAILAALRGQQLLAS
>A0A660ZMD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
DGFNHGVDPTGKRLDDTTNFHTATGVEPGALDYDRELRRLERKVAAGADFVMTQPVFDPR
TMERFLKDTSDLDIPILLGLLPLASSRNAEFLHENVPGMNIPEDVRKRMASAGSGEKARA
TGVQIAREALLDLKGRVQGAYIMPPFGRYEMAVQILDGIER
>A0A7L1XL54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thinocorus orbignyianus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAIDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A1G9PXW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium mycetoides|TrEMBL
MRIYRFFSQRQTVSAEPGQATRVRKKGILVPERFPSTRLSASAPLDRLDEDPATTPVVGP
RAARTALSFELIPPRHDADTALLDTLIAGLAEYNPDYVSVTSSRRSDWLEGTAGLISRIA
ETTDLKPIAHLACTAGTRGELAGWIRALIDAGVRGFLALRGDLPDGVAQLPEGYLQHATD
LLNLIVEVQEEQAFRLAAGKLALSVACYPSGHAESKNADMDLDVLLAKQRLGADFAITQL
FFEAEDYLSFVEKSRLAGVRIPLIPGIMPMTSLRRVERMGVLSGIKVPECVTRRLSAASS
PEEEYEIGMEMTADLTRAVLEAGTGGLHIYTHNNLAVTRDLLSRINI
>A0A497P3C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MSYISSLEKSLATSKFTITGELTPPKSASIEDLLDGAKLIKDDVVATNVTDNPTSRVVMS
TLATCHLIEKQTGLETIYQITCRDRNRLALQSDILAANALGIKNILVLTGDYITMGDHPE
AKPVFDLDSVQLLWAIKRMQEEGVDLAGKQLKTPPKLFVGAAVNPGIDPLEPEIIRLEKK
VAMGAKFAQTQCLYDPAVLEKFMDQISHLDVKILVGITPLLSAGMAKWMVKNCPGVIIHD
EMIKRLKGAEDKVKEGIKMIVEVVSEIASMGVAGIHVMVPERADLVAETVKAIKASGVV
>A0A537HGP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MRLSDRARHHNLVTVELIPDRVVPSDLSLLRGRVDAITVPALRNGHDDPSYPKSFSITPQ
RRSLASASIINRAGITAVPSLTCRDCNTSDLSAIANHVVQGLRNVLIVYGDPFPQPHPGS
YQFAKTNELIREISSLNGGNDPCIGAVTNQHADNRESEISRTISRVDAGADFIVTNVAFD
SESVLEHRDALLEAGLNVPLFIQVSIPLSLDNVLFVSQKFDIPVPVHIRKKLLDDPTGGS
LAVAAEAYEALRGEANGIHFSYLFRRRNPIPTYCHLLETIGIEGPTLAPLATSAVKTYPV
A
>A0A7J3L0F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
SLEITPPKRDVEKVVNIVKQVRDSVDAVNITDTPLGQPRIPGFIFAIILRERLGVEPIVH
YKTINMNLTNLKSVLYGCVATGVKKFLFMRGDNPIEGSPISDISPEELSMWAKKELNVET
GLAVSWPISMDKLISKLSARPDYVFTQIFLSIEDAKRFRSMFDEAANKVGWFPPVYCTHL
VFCEENLSTLKEVARLMGLEMPSFKLDVETNVNFITELERFFEGFMISSPGGYDHAIQLI
KTLKEA
>A0A497LF96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MFRELIKEKDVPITYELWSPRGCMVNQHFEAVSRFKDKLDAVNIPDNPLATLRVSSIAYS
KIVMDHLKIDVIPHINCRDRNSLALQSDILGAHLLGIRNLFIVGGDKPAGKTVKTKGVWA
VTSTELCKIVKHLNEGFARSNDDLVEIHGKTDFFVGGAIVFDRKNEVEIISRKIEAGFDF
FQSQIVFSHEKVLNFFREAEERGVTINKPVLVGLSPQPSEKALNKLVRFLRVEMPKSSAD
RLRRSGDFASEMLSVCLEIADELKSALSPKYKIGFHIMPLGYDDLGRKLVEELRE
>A0A3B9Z830|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MQISKLFDGDKTVLSYEIFPPKRNDSIDKIYDTIEKLSDLNPDFISVTYGAGGNIADSKT
ADIAQLIKDKYNIESVAHLTCINTGKEELDYILNDLENKGIENILALRGDINPDIKPKKE
FKYASELATYIIKRGGFYVSGACYPEVHVEAEDSIADIKNLKKKVDCGVSHLISQLFFDN
EVFYAFKDRARAADINVPIEAGIMPVTNKKQIERMVTLCGASLPAKFVKVLQKYEDKPEA
LVDAGIAYAVNQIVDLVANGVDGIHLYTMNNPYVARKITESVKNIL
>A0A378TM62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium tokaiense|TrEMBL
MCCPKRMDFGPCGGVHPDGSCEMRPGPCAFPEVVPWSGPVADGVPVTAPLVLTDFSAAPF
DPADLVATAELLAPACDAVLVGEHQNRPDFPPTLAGRMLLDSGVSPWITLSCRDRNRIVL
EQELRGLRQVGVQTVFCVTGDGRGYDVRPDVTQTFDLDGPRLLSLAAALGVTAAAPETPT
APPVTGRPARLVQKQRAGARIAVLNHVPYPAQVAAFMAEARALGLSIPVLAAVAVFTDPW
SAAILEGLPGLELDQEVVAQVINARDPVEAGIAAAVAEARALLAIDGVDGVNLSGSASSA
GTRVGAQIKAEVGQRIRTEFA
>M5ERR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium metallidurans STM 2683|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIITRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHDDITETQVDMVK
TAH
>A0A231MUR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zobellella denitrificans|TrEMBL
MAFHSARHVEALNQSLAELNGDINVSFEFFPPNSEQMEQTLWHSIERLKTLAPKFVSVTY
GANSGTRDRTHKVIKDIQDKTGLVAAPHLTCIDASRDELRGIARDYWNNGIRQIVALRGD
LPQGMEKPDMYATDLVSLLKEEADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTIGIDVEIVPGILPVSNYQTLIKFAGFSNVKIPGWMHQRFQ
GLEDDQNTRNLVGASIAIDQVRVLSREGVKDFHFYTLNRSELTYAICHTLGVRPQAAK
>A0A2T0U3X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcticibacter pallidicorallinus|TrEMBL
MFLDQIKNGKPGILTYGITPPKAGTPPARIAEIAERTMARLVGLDIDALIVYDVQDESAR
TSEERPFPFLNALDPFTFASEYLGGLNVPKVIYRPAGKFSKAELTAWLDQLGRHNCYPVF
VGVPSPGFPVKTTLPEAYQLWSKRVSTSVIGAVTIPERHSVLKDEDQRILDKAASGVSYF
VSQCVFNVDFAKKLVEDLCQACREQQISPPSILFTLTACGSFKTLQFMEWLGIHIPEALK
EELRQTENMLERSVEVCLAIAAELTAFCADRCVPFGFNVESVAIKKDEIEASIYMVNQIG
KMLSEKGLRNAPRPFLASL
>A0A554S9I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Inquilinus sp. KBS0705|TrEMBL
MKITEHIANANGKTLFSFELIPPLKGQSIQGIYDAIDPLMEFKPPFIDVTSLREDYIYKE
QDNGLLEKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLVDLQFLGIEN
VLVLRGDARRGDSSFVPTPNGHCYATDLLQQVVNMNNGIYLHENYEDIMKTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGANFIVTQMFFDNQKYFDFVNNCRANGINVPIIPGLK
PITTSKQLVNLSKTFHIDIPEDLSDAIHDCKVEKNVKDIGIEWMINQCKELVKFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A3B8UR01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKVTEILKQDKPTISFEVFPPKKDTDFADVEAAATSIAELNPSYMSVTYGAGGSTKGLTI
KLAEGIQNKYNVPTIAHLTCVCADKTGISQALEDMKAAGIKNILALRGDIPKDYAGEIFT
EFAHASELVKLIKASGDFCVGGACYPEVHPDSTDKKADIEGLRKKVEAGCEYFTTQMFFD
NNIFYNFMYRIREAGIMVPVVPGIMPITKRAQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMRQAGVLYATDQIIDLIANGVNHIHIYSMNKPEIARAIYDNLSHIII
>A0A1G3KZ48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium GWB1_36_13|TrEMBL
MNIQEVLSQKFSFSMEVFPPKKEGDVKELFQVIKDLKILNPDFISVTYGAGGSTQSMTRE
IASEIKNKIGIESMAHLTCVGNTKEEISAIINDLRESNIKNILALRGDPPAGMKEFQVKQ
GGFAYASELVDFIRQNQNHFSIGVAGYPEKHPEAGSLEKDIENLKKKIDAGADFIVTQLF
FENEAFNRFMDKIEKAGIRIPVLPGIFLVSGYNQLKRITELSNAEIPKKFHDNLLKYQDK
PEDLKKIGIEHALMQSEDLIKSKRIGGLHFYIMNRKDMILPIYEELKGFF
>A0A348SAM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNQYHVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAGNKVEDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>A0A173Z6F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor plautii|TrEMBL
MMDIRTYLSQGKPLLFDGAMGTYFAAHPGRAEERCERANLTRPEEILRIHRAYLQAGCRA
IKTNTFAISGDLSDGNDETACDIVNAACHLARQAAQPYGAYVFADLGPAPRDHSRAPADL
YQTQAQWFLEQGVTHFLVETLSGDEGLPELAGWLKEKNPDAFLMVSFAVDHSGMTSAGRL
GSELYRFASELAGVDAVGFNCVSGPRHLLKYIQTLELSDKPLTVMPNAGYPTVLGRRTVF
GGQPDYFAGQIAQIVQAGASIVGGCCGTTPEHIAQTAQALKEPLPKCTVSAPKKLLKPAA
NASNSLWEKLEAGKRVIAVELDPPVDDDSAGFWEGVQALRGSGADAVTIADCPIGRPRAD
SSLLACKIKRDIGIEPLPHMTCRDRNLNATKALLLGLSMEGVHNVLVVTGDPIPTEDRNE
VKSVFNFNSRKLARFVHMLNENTLRTPFRIYGALNLNARNFDVELRRAQEKEACGVSGFL
TQPVLSAEALDNLKLAHKTLRGKILGGIFPVVSHRNACFLNNEISGMRVCDEIIHLYEGK
DRDAAEALAVTVSTAIAKEIFPYTDGYYLMTPFRRVALMEHIIQNIQQSHIS
>N9XJ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] clostridioforme 90A7|TrEMBL
MKTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTRDDVLLILEQLKEQKIENILALRGDRTADREPAGDF
RYAADLVEFIKNHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFRERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFISMMERYGDNPIAM
RDAGIAYAVDQIVDLAAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>W1EN87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae IS53|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A5C4PJK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurellaceae bacterium USgator41|TrEMBL
MSYAKEIDHLNHSLANLNGEINVSFEFFPAKNEKMETLLWDSIHRLAPLKPKFVSVTYGA
NSGERDRTHGIVKRIQQDTGLIAAPHLTGIDATPDQLRVIAQDYWDSGIRNIVALRGDEP
PGYAKQPFYASDLVKLLKEVADFDISVAAYPEVHPEAKSAQADLLHLKEKVAAGANRAIT
QFFFDVDSYLRFRDRCVAVGIDVEIVPGILPVTNFKQLQKMATLTNVKVPSWMPKMYQGL
EDDQTTRNLVAASIAIDMVKVLSNEGVKDFHFYTLNRSELTYAICHMLGVRATV
>A0A522LF19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MSQSSPLPVSFEFFPPKTPEGVQKLRVVRQALYAQKPEFCSVTYGAGGSTQEGTFAAVRE
ILAEGVAAASHFSCIGATRASVREQLGQLKAMKVRRLVALRGDLPSGYGTGSEFHHASDL
VAFIRAETGDHFHIEVAAYPEVHPQARSPQADLQAFAAKVKAGADSAITQYFYSVPAYLR
FVDETRKLGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDDSAAIRAFG
LDVVTELCALLRGAGAPGLHFYTMNQSTATLAICHGLGL
>A0A351J5Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MARLLNRLTQGQFVVTVEIDPPRGPDAAKTLEKVRGFADRVDAVNVADCPMANVRMSPIT
LAHLIQRDAGVEAIFHLTCRDRNTIGLQAELLGAAGLGVRNILALRGDEPTRGDHPSATG
VFEIGSSRLIKLAS
>A0A1B0VKS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium islandicum|TrEMBL
MKVSEIVKEKRIISIEIIPPKRGENVENIYKSLDKLMKYDISFINITRHPVAVDYIEHED
RIIKVQKVKRPGTIGLTAALMNRYKIDVVPHLVCVGMNKFEMEDTLIDLDIMGVDNVFVI
RGETDQNNGSYTKGDYRYAVDLVQQIRDLNSGKYLYTKAKPTNFCIGVAGYPEKHYESPN
AETDLKFLKQKVDAGADYIITQMVFDAEVYRSFVERCRMVGIDVPIIPGIKPVVSKSSVF
NIPKKFFVNIPQKLVEAIDNAKTKEEEFRIGISFTVELVEKLIEYGAPGIHVFTMGRGEE
SCEVIKFAQSIIK
>A0A3M0IV05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hirundo rustica rustica|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLNSATQQ
>A0A7W9EZH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loktanella ponticola|TrEMBL
MALLNFRKKPVETDMVSPNVSAFLNGYSIEVMPRTAEKVIDFQSLLPAGTRVYIAHIDGT
PIDDMVATAKRLAADGMNVMPHFPARIIKDHAMLADWIARYQGEAGVDQALLLAGGVAEP
HGDFHSSMQLLESGLFDKAGFQRLHVAGHPEGNKDIDPDGSDANVMDALRWKQKFNETTD
ADMALATQFAFEADPIIAWADALRDAGITIPIHIGIAGPAKLQTLIKFAIACGVGPSLKV
LQKRAMDVTKLLLHYEPTDIVTKLADHKAANPDFNIDSVHFFPLGGIKTNANWAIAQGGD
STIPANPNKTPE
>A0A2V2ER55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MKISELFQKKKAVYSFEIFPPKPSAELSAVQGTIEELSALHPDYISVTCSAGGSGNSRTG
EIAKLVRGLGVEPLAHVTCINSDKTSVRAALDLLQADGIENVLALRGDRIAGAEDSKDFA
HACDLVRFIRENGYDFDIAGACYPECHPECSDILTDIRNLKKKVDAGVTHLNTQLFFDNE
DFYRFRDMLSLAGIDVPVQAGIMPLVKKGHVDRIISLSGAKIPAKISRMISHFYDKPDSL
MEAGIAYAVDQIVDLLSAGVRGIHLYVMNNPYVARRISESVSHILGEINAD
>U6FBU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus CIRM-BIA 104|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKLSAILDRYQNSEEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHRS
>A0A345YNE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium saurashtrense|TrEMBL
MPPRSSRRPTSRPWPARPPPVPEPAERAAAAPEPASTPLPAPAPRRAQFEVIPLPGVLEQ
VLEHLGPGTRVTVTASPAQGLEATVETAIALAGAGRVAIPHLAARMLTGERELETILERL
AGAGIEELFVIAGDADPPAGPYDGALALLEALRPARRGLAVGVGAHPEGHPFARPDEALE
LLRRKAEHASYLATQMLFAPVPLVDWVRQLRAAGIDLPVRPGLAAPASRARLLRIGARIG
VGRSLRMLSAEGSGVRRLLSPGSWDPEPLRVAIAAAEVPGIAAPHVFTFNSLAETAAWWH
GRAQRS
>A0A3N4HA97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclobacteriaceae bacterium YHN15|TrEMBL
MKISEYIQQADKPLFSFEILPPLKGQSLKDLCEGIEPLMEFRPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFKIDAVPHLLCGGFSKEETENALIDLNFIGVQNI
LALRGDAPKSENKFVPEPNGHAYTKDLVLQIVGMNHGRYLHEETETGFHTDFCVGVAGYP
EKHFEAPSMKFDLKHLKEKVDAGAEYIVTQMFFDNQKFFEFVRKVREMGISVPIIPGIKP
ITTLGQITMLPRTFYLDLPDALMDELEKCKTNADVRDVGVEWAIHQSKELIANGVPVLHY
YTMSKAEATYRIAKEVF
>A0A1G5TRY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. UNC378MF|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTDEMEKILWNSIERLAPLQPSFVSVTYGAGGSTR
ERTHNTVARMVRETGLKPAAHLTCVDASREEIDAVVQSYWDAGVRHIVALRGDPAEGVGH
AYRPHPEGYASTAELVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQA
ITQFFFENEIYLRYLDKVRAAGITIPIIPGILPVQNFKQAANFARRTGASVPYWLAARFE
GLDDDKETRRLVAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AAKAAA
>A0A8H7A1D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pleurotus ostreatus|TrEMBL
MKLSEKIASYTSSRPFYTFEFFPPRTDQGFENLVPRITRMAGLNPLAVSVTWGAGGSTKD
RSLELAGIVQREHCVDTILHLTCTNMEKGLVDEALRAAKDRGIQNILALRGDPPRGEEDW
IATDDRFTNGKNLVSYIRSTPEFASDFAIGVAAYPDGHPESSLTEEEEIANLKDKVDSGA
DFIITQLFYDVDGFLRWLQKVRDAGITVPVIPGIMPIQTYASFQRLIKLCGSRVPPSIMA
ELEPISNDDQRVKNYGVSLAVSMLRKLSASGIKGFHFCTLNLEKSIQRVLETLKWTGPST
LEQNKLIVDSELTVSPHNATGSAKMHLMNLPEVEGEAGKGELNNAATWDDFPNGRFGDFK
SPAYGDQGPWGGLLISRNEALIQWGRPKSVQDLTKLFVDHLHGRRASTPFSRGPLIPESQ
MILPQLERLNEREWWTVGSQPAVDGIDSGDPVIGWGPRSGYVFQKGFVEFFCETKDVDEL
EKRLDIHGKGWVHLIASNYKGEIRTNIPEGARNAVTWGVFPGQEIVQSTIIEQASFLNWK
EEAFAIWSEWSSFYRPGSEERKLLENIRDTRWLVSIVHHDYKKADALWQFLFDGQ
>A0A0N8NTW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxobacter pfennigii|TrEMBL
METKINKFKESLLDKDTLSVTWELVPGRGAHEKAQEEAIEYAEQAAKGGRVHALTLTDMP
GGNPAIAAESLAAEIVKLGIEPLVHFTCKDKNRNQIEGLLYALDRAEARNLLIMTGDYVY
TGYTGRPKPVFDLDPMHVLSLVNEMNDGLEYKGMRGTIKHKPSDFFAGAVSSPFKKTEAE
QMAQYYKLKMKVASGAQFIISQIGFDARKIHELIHFIKSNGWDIPVVGNIYVLSYGTAKL
MNNNKIPGCVVTDKMLKELEEESKAPDKGKAARMLRAAKMYALFKGIGYAGVQIGGHGIK
YEDVEYIIDKGEELSKDWMSLIPEFNYPIPDGFYYYEKDEKTGLNIDKFTERKGRPLDTK
VELVYPLSTFTHALMLEPGTPLWGPMKFVCKNIEGTKLEKAFHFVEHMAKTALYDCKDCG
DCALPDVGYVCPMSQCPKNQRNGACGGSYDGWCEVYPGKKKCAYVRAYSRLKKKGHEHEL
DHDVNTPLNYDTYQHSSWINMYLGRDHNAAKYGVERIEKKK
>A0A2E9PGE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp|TrEMBL
MVSYAQGVDALNQSLSELRDIDVSFEFFPPKSEKMEQTLWKSVERLAPLNPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVQKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTSVFLRFRDRAAAAGIDLDLVPGILPVTNYQTLVKFAGFTNVHVPGFLHKMFDGL
DDDDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRGNAAK
>A0A1V6UA70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium coprophilum|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKVLGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRQTHGDYFCVGVAAYPEGHPADTFQDVQDPVRDIPY
LVEKTLAGADFIMTQLTYDIEAYKKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIAKRMEELKHDDDAVKRAGVDIVSEIVGGIRDIPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPSFSDAGDLAIEDDPASIPLDFPGRALRRRRASSLNSQPHNRVIVDKL
SAHDSSHASDHEARADSAGMPAPPPNRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHMTANSARRLWGHPVDDKDMSALFRRHVSGELHMVPWSEGGAEEDGDG
LNAETELIRPELLKLIEGRGWWTLASQPAVNGVRNDHPIFGWGPQREGFVFQKPFVEFFC
SNNDYTKILKPTFAKHGHDKLTWFATNIKGDFASSLPTQPADMELDDLGDNPDSVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTETYLDTTKNDAWLVCVV
GQQFGAGTKRGSKEEEDEVKWMWRVLAGEDV
>A0A4V3KAS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1D.F.Ca.ET.234.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAPRDQVDAVIREFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A1F9MXG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca sp. RBG_16_58_9|TrEMBL
MRLQEKLASGEFVILAEMEPPKGTDVSAMVANAANVKRMVDAFMVPEMSNAVMRMSSLGG
ALLLQSKGLETVMQVCCRDRNRLALQGDLLAAQALGVPTVMAVAGEEITHGDHHQAKAVN
DLDLLELLGAIQSLQSGRDLAGVDLKGAPQFLVGSTVKVPGGGAALEAELAEMDKKIAAG
ARFFTTPPVYDLAALETFRQKVGQRQAAIIPTVLLLKSVGMARYINRHLDQMKIPEDFIN
RINKAADRVRECVQIAAEIVAALKDKGYHGVLLSTIGWEDKLPAILAAAGV
>A0A1M4ZWP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dysgonomonas macrotermitis|TrEMBL
MKVTDLIAKNKGKTAFSFEILPPLKGNSIEKVYNIIDKLIEFDPKYINITTHHSENIYKD
MPDGNVRKVNVRKRPGTVAIAAAIQAKYKVTAIPHMICKGFTREETEYALIDLNFLGVHN
LLLLRGDANKLDADQMIGNFNAHATDLQMQVEQFNKGVSADGTTFDKFTTPFSYGMACYP
EKHEEAPNFESDIYYLKLKQEQGAEYLVTQMFFDNKKYFSFVDKCRAEGITIPIIPGVKP
ICLQNQLTVLPRIFRSDIPEELASELRKCKNDADAKEIGVEWGIQQTRELIAAGVPSIHF
YSLMATESVRRIAKEVY
>A0A1F2HMZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC10E12|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKDQAPQFDIIGACYPEGHPDSANQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHEATHSLFKHHSQVGAL
>A0A436WDC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M4A.F.Ca.ET.020.02.1.1|TrEMBL
MTIRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>R2T2C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus pallens ATCC BAA-351|TrEMBL
MQSAKTSLSFEVFPPTSKATNDSLFTSLKQMEGLSPDFISVTCSNRQTSLEDSTVKIAEH
IQQQHQVDSIVHLTAAYLNEEEVDTILTSLQQKGLQHILALRGDLYPDVQRNNDFLYASD
LIAYIKHWDPSFSISAACYPQGHPESSDTVEDIHYLKQKVEAGADQLITQMFFDNQHFYQ
FQENCWLAGINVPILAGIMPIINKRQAERILRTANVQLPKKFMAILDKYADNPVALRDAG
MAYAVDQIVDLVTQGASGIHLYTMNNASIARTIYKATHSLFDLETITAVGSA
>A0A177M2J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas methanica|TrEMBL
MNISFEIVPRSLEAFDQQYGFVQTLDKGINIINVPDIQRFDTRSWELATRVDRSKYRFIP
HFRAIDFKIESGDLYRIIEEYALDSVLLVSGDPPEGLKRSFYNTDVVDLIRAVRQRFPSL
HIYAGFDPHRSGVQDECDYIQRKVDAGAGGFFSQPFYDSRMIDIYAEHMQDLETYIGISP
ITSKASMNYWEVKNKVKFPKSFRPDYDWNVQFANDVIASAAANGLNVYFMPIRIDLARYF
GEIELGG
>A0A4R6J2Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sediminibacterium goheungense|TrEMBL
MKITEHIQQAKDTLISFEVLPPLKGKTIFSLYDHLDPLMEFKPSWINVTYHRSETMFKKK
ADGTFEKVEVRKRPGTVGICAAIMNHYQVDAVPHIICGGFTKRETEDALIDLDFLGIDNV
LALRGDAAKNESAFEPEPGGNHYALDLIRQVNNMNNGLYIDEDIKNGGKTKFCIGVAGYP
EKHFEAPNLEIDLAKLKEKVDAGAEYIMTQMFFDNQKFFDFVKSCKDMGIHVPIIPGLKP
ITNKKQLSVLPRIFHVDIPTDLSNAIMKSKTDAECEQVGTEWLTQQSRELKAFGVPVLHY
YTLGKPKVIWNVVKELV
>A0A209AVE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia frederiksenii|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTELRDIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLKRFATMTNVRVPNWMNTIFD
GLDDDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A0D0B2J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Suillus luteus UH-Slu-Lm8-n1|TrEMBL
MRISKKIEQSNKEGKIWWSFEYFPPRTAQGLQNLLDRIKRMTALGPEFIDITWNAGGRTS
DLTSHMVKTCQGSVGIETCMHLTCTNMPKEKVDIALREAKKAGCRNVLALRGDPPQGKDE
WEAVEGGFVHGIDLVKHIHNEYGDYFDIAVAGFPQFQLLPPAERDLEMKYLKEKIDAGVN
FIFTQMFYDVDVFIDWVNAVRAAGITIPIVPGIAPIQTWNGFLKATSLANTKIPQSFLDA
LEPYKNDDEKVREIGTKLVAEMCRKILAAGLGIQGLHFYTMNLEKGTKMLLEELNLMPRV
ETIKPLPWRQSLTPNRRQENIRPIFWANRTESYLSRTEDWDEFPNGRFGDSRSPAYGELD
GYGIWLKQTKEEALKLWGEPKTFAEVALLFSRFCLGQLKALPWSNQAASSETSAIALQLA
KMNELGFLTINSQPAVNGMRSDDPQFGWGPSNGYVYQKAYLEFFVSPRLLELLLAHVERD
SSMTYYVINKQGDLRTNTHSEGPNAVTWGVFPGKEIVQPTVVEALSFMAWKDEAYELGVK
WANVYEAESPSRKLMMEIFESSYLVNVVHNDFKDPQAIFEPFFKAGAEYAAQHTNGSAAP
QALPN
>A0A0A3IXI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus boronitolerans JCM 21713 = 10a = NBRC 103108|TrEMBL
MGLLERLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLDEI
LATIEEQASVLLAGNPDGLLLETYYDFEELTATLKMLREKTNLPIIAQVSMHEPGVLQNG
MSLNNALHELEALGADIVGVNCRLGPHHTILAFEGVELPNKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVQEKHAKPEKIEI
VREAEPPKYEPLHEKVKRERSVIVELDTPRHLEIDGFLEGAKQLYDAGADVVMMADNSLA
SPRISNIAMGALLKSTHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDVLAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVTR
LEKKIEHGADYFISQPVYTKEKIVEIYEATKHLQAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSEDALARMKVCGEDKERAKLEGIAIAKELVEVAAQYFNGIYLITPFLRYDVTLELMKY
IEQLDEQKKGVSIHG
>A0A8I2ZHR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium longisporum|TrEMBL
MVTTPYSEALPTFWNGLLPLPPLLHLEMLADAERDGQPSFSFEYFPPKTAQGVQNLYDRM
DRMYNFGPKFIDITWGAGGRIAELTCEMVTQAQSVYGLETCMHLTCTDMGLDKVNDALRK
AYKAGCTNILALRGDPPREKEKWVAADGGFEYARDLVKHIRATYHDHFDIGVAGYPEGCD
DNKDEESLLDHLKEKVDMGATFIVTQMFYDADNFVRWVGKVRERGITIPIVPGIMPIATY
ASFMRRAKHMNCSVPQEFMDALEPVKNDDNAVREVGKVLVAGMCRKILAAGIHHLHFYTM
NLAQATRMVLEELNWMPTSERPLKQALPWKQSLGLGRREEDVRPIFWKGRNKSYILRTQD
WDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEQNIKKWGEPQTVQDIATLFVRYLRNEID
CLPWSESPLTNEADPIREDLIALNKRGIITINSQPAVNGVKSSHAVHGWGPKNGYVYQKS
YLEMLVHPDLYPEIISRIEKHPDMTYYAVTKSGNLKYNAPSDGPNAVTWGVFPGKEIVQP
TIVEGISFVAWKDEAFRLGLDWAHCFEQSSPSLNNDFHQQREIFDLFEGLSVKEYDDIKP
VAKDVAPDAVSAPTNGTTNGIAVPAA
>A0A839T8E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azomonas macrocytogenes|TrEMBL
MTISNRPNISFEFFPTKTDAGHQKLLANARQLAGYNPDFFSCTYGAGGSTRDRTLTTVLQ
LDSEIKVPTAPHISCVGDSKAELRELLNLYKNAGIRRIVALRGDLPSGMGQASGELRYAN
ELVEFIRSETQDHFHIEIAAYPEMHPQARNFEDDVANFARKVRAGANSAITQYFFSADCY
FHFVERATGAGVEIPIVPGIMPITNYSKLARFSDACGADIPRWIRKQLEAYGDDSESIRK
FGEQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLGLGS
>A0A841A066|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum rhodesianum|TrEMBL
MPSASRHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVNATREEIDAVVQSYWDAGVRHIVALRGDPAEGVG
HSYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFDNEIYLRYLDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLDNDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
PAAKAA
>A0A1W9U3A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterium sp. 4572_20|TrEMBL
MNTKTPSKLEKILAAGHLAVTSECGPPRGSDGDVITKKAEMIKDYVDAINITDNQTAVTR
LCSLAAVIRLKLMGLEPILQMVTRDRNRIALQSDILGAASFDIYNILCLSGDHQSFGDNP
QGQNVFDLDSMQLAQTVRHMRDEGKFLGGDDIDRPPQMFVGAAANPFADPFEIRVRRLAK
KVAAGVEFIQTQCIYNLDKFELWMKQVRDTGLHEKVYILAGVTPFKSAGMAKYMKKRVPG
MDVPDEVVERMSGVPKEKQPEEGINICVESIQRLKEVEGVRGFHIMAIEWEEMVPEIVKR
GGLYPRPKIE
>A0A1F5V2M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fraserbacteria sp. (strain RBG_16_55_9)|TrEMBL
MTGESNLKRILESAGFAVTAELGPPKGADRHVIENGAKLLGDWVDAINITDNQTAVTRMS
SLSACAIVKSMGLDPVLQITARDRNALAIQSDILGASALGIRNVLCLTGDHISMGNHPKS
KGVHDIDSIQMVQMVRKMRDEGVFLSGDRITGEKPAVFIGAAENPLAPPPEFRVVRLGKK
ANAGADFIQTQVIFDVERFRVFMAQVRERKLHEKLAILPGVMPVKSAKVMNYMNTKVPGV
RVPDELIQRMQASPDAKAEGVTICVQLIQALKEIEGVRGVHIMAVQWEEVVPEIVERACV
RKKQPVGKFA
>W4P8F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides pyogenes JCM 6292|TrEMBL
MRVIDLIHNNTKTAFSFEILPPLKGTGIEKLYEDIDTLREFDPKYINITTHRSEYVYKDL
GNGLYQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFSREETEYVLLDLQFLNITDL
LVLRGDKAKHESSFTPEKDGYYHAIELQEQINRFNQGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMEADLYWLKKKMEAGAEYAVTQLFYDNKKYFDFVKQAKAAGIHIPIIPGIKP
FRRTSQLSMIPKTFKVDLPEDLVKEVLKCKNESEVEQIGIEWSVNQCKELMSFGVPSIHF
YSIGAVESIKEVAKLIY
>A0A316HMD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fulvimonas soli|TrEMBL
MPSISFEFFPPKTEEQRAQLDRTTALLKPHAPDYVSVTFGAGGSTLSYTGETVARLHREH
GLEVAPHLSCMGGTRQEIAALLDGYRAAGYRRLVALRGDLPSGMASPGDFRYAAELVRFI
RAHSGDHFHVEVAAYPEIHPQAEDALADLKHFKAKVEAGADGAITQYFFNPDAYFRFVDD
ARRLGVAVPIVPGIMPIANFGQLKRFSDACGAEIPRWIAKRMQAHGDDAEAIRELGADVV
AQLCRRLLDGGAPGLHFYTLNRARPTLAILDRLH
>A0A1F9LB96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYC2_FULL_48_10|TrEMBL
MKTESKLERILASGNLAVTSECGPPRGARPEKVREKAALLKDHVDAVNVTDNQTAMVRMS
SWAAGVIIKQMGMDPILQMVTRDRNRLAMQSDIIGAYSLGINTMLCLSGDHPKFGDHAAA
KSVYDLDSVQLVRMVQKMRDEGKFQGGADIDCPPKMFVGAASNPFAEPFDLRVSRLAKKI
KAGADFVQTQCIFNLDKFEKFMEMVCDRGLNEKVYLLAGITPMKSAGMAKYMKNKVPGMD
VPDEVIKRLEGVSKAEQPEEGIKIAVESIQRLKEVKGVHGFHIMAIEWEEKVPQIVEKAG
LFPRPAVENL
>A0A5B5VRP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes finegoldii|TrEMBL
MNVLDIINTAIAEHRTRFAFELLPPLKGDGMGGVFAAIDRLIGFDPAYINVTFHREGIKQ
SVRPDGGIDWHVVRRRPGTVGISAAIQKKYGVEVVPHLICGGQSKYDIEDALIDLDFLGL
HNVLALRGDKSQNEKFFMPHPQGHSHAVDLVRQIAAMNRGEFVDGEVEECHHSKFSIGVA
GYPEGHEESPSPEADIAALKAKIDAGAGYIVTQLFYDNARFFDFVRRCREAGIAVPIIPG
IKPLSTLRHLTLLPQTFGCRIPEELEREVLRHREDPKAIREVGTEWAVAQSRELKQAGVP
VLHYYPMGKADNIIKIAKAIF
>A0A5C5Y5J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crateriforma conspicua|TrEMBL
MKLTSAYQSADCTISFELFPPKTTAGLDKLCQNVDRLTDFGPKFMTCTYGAGGSSQGMTL
DVLRQVKSRTNLPVASHLTCVGATVPQLCDFLQQATDAGVDYIVALRGDPPQGSDRFVQT
EGGLQYANELVELIRERFNHFGILVAGYPEVHQEAPDAQTDLTNLKRKVDAGADVVVTQL
FYDNADFYRFRDDCDRAGITVPIVPGILPVTNFAQAKRIATMCKSAIPASLEDAFAKCQN
ADQEFEIGVEHARRQTIDLMENGVPGIHYYVLNKTEAAERLLQGLSFAV
>A0A1I7KYG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. INlla21|TrEMBL
MKVSEIYKSGKKTLSFEIFPPKKDEALKNIDATLEVLTELKPDFISVTFGAGGSSNRNKT
IDIAKKIKHEYHVEPVVHLTGLQYDKNEIDEFARVMKDEGIENVLALRGDRNPQLVEKDD
FKHASDVIKYLKEKYDFCLLGACYPECHPESESRVSELKNLKKKADSGASALLSQLFFDN
DKFFNFYDECRIADINIPIIPGVMPVINAAQIKRMITMCNASFPERFQKIINRYEDNKEA
LFDAGMSYALSQIIDLLVSDIQGIHLYTMNNPLVARRICEGIKNIV
>A0A2A5W571|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceicoccaceae bacterium MED-G30|TrEMBL
MALITEQLTEGIAQGPIFSFEFFPPKTESAAAQLLHTAEKLRHSQPDFVSITYGAGGSTR
ERTLHYASTLQDKFGYEIMPHLTCVGHSKEELRSTIEEFKDAGFKRIMALRGDPPKGEHN
FTPHPKGLRHANELVELIRQVHPECAVAVAGYPEKHPEADSPEADLIHLKRKVDAGASFI
TTQLFFDNSVYYRFVENCRDVGIHVPILPGLLSIASREQAMRFCRMCEATFPEALDKNLL
AAGEDPHLLRLAGDQWILEQASDLLQNGAPGIHLYILNQADAALTLHQKLQSSGILPKK
>A0A1V4SDE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4484_190.3|TrEMBL
MKLKESLEKKKFVVTSEVQGAVDEAPEQLVKSLELVRGRVDGVTVPEVEIEGVVGDSIKT
CEVLNKNRFEAIYQTTTRDKNRIQLQKDLLQAHDSGVENLLVFTEDYRITGDSLQEMMFF
HVDAGKLESVLQHMREGRTVDGGELGKGADFVVGSGVESGWGKNIPDLEMKEMEAMAKIG
AGYFLSTPVFDVDGFEKFLKQVNTFGIPVIAEVMILRTAGMASFLNRHIKSGMVPEWVIK
KLAKAIDKEKASIEIFADTVKGLKDLCQGVHIITIGGEEKLRHYLDAAKLK
>A0A1G8QHR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliiruegeria lutimaris|TrEMBL
MPAPHVSFEFFPPRSVEASFRLHETVKALAPLKPEFVSVTYGAGGTTRRLTHEAVSAIHR
TTDLRVAAHLTCVDATREETLEIARTYAAEGVTDIVALRGDPPKGATRFEPHPEGFADTC
ELISALRDSGDFTIRVGAYPDRHPEATSDLADVEWLKRKIDAGAHEAITQFFFEAETFFR
FRDACEKAGIDAPILPGILPIEHWGNTKRFAQRCGANVPAWLDEAFANAERDGREELLAI
AVATELCSDLIEGGAGHLHFYTLNKPHLTHDICHAIGIVQDATLQDVA
>C9YE70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Curvibacter symbiont subsp. Hydra magnipapillata|TrEMBL
MLYLCPQGGLNPVPAMQARETEMTMSTNQRIPLSLEFFPPKTPEGAEKLRTVRQQLYGLK
PEFCSVTFGAGGSTQEGTFNTVRDILSEGVSAASHFSCVGATKSTVREQLATLKAMGVKR
LVALRGDLPSGYGAGGEFHYASDLVAFIRAETGDDFHIEVAAYPEVHPQAKSPASDLQAF
ATKVKAGANSAITQYFYNSDAYFRFLEEVDALGITVPVVPGIMPITSSTQLMRFSDACGA
EIPRWIRLRLQSYGDEVASIKAFGLEVVTDLCEQLRAGGAPALHFYTMNQSAPTLALCKN
LGLDA
>A0A1F3JUT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWF2_33_38|TrEMBL
MNNKKVTDYINESKNPLFTFEILPPLKGHNIDTIYQAIEPLLEFGPSFINVTYHQQEEEF
KTREDGLIEKKTVSKRPGTVAISAAIKYKYKIPVVPHLICGGFSQEETEDALLDLHFLEM
RNLLVLRGDPQKNQRRFTPEKGGHEHSLGLIEQIMNLNKGIYLDNEMKNKTTTNFCVGVA
GYPEKHAESPNMEEDLKYLKQKIDAGAEYIVTQMFFDNKKYFDFVKLCRSKGINVPIIPG
LKPIANFNDVKVIPQIFSIDIPNELIKEVSKCKTNDEVCKVGTEWTIQQSKELIKFGVPS
LHYFTIGKSKNIKKIAKEIF
>A0A6I6AF55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia benthica|TrEMBL
MRISEIYRSGTFGLSVEIFPPKNESGDAELFRTLEELVRYKPAFVSCTYGAGGSTSKRTI
ELCNTIQKDLHSTATAHFTCVGSTREQLVDWLKEASEAGIGNIMALRGDPPKGEETFIPA
DGGLKYASELVTLIRENFPEMGIGVAGYPEVHPEALTPQADLENLKRKVDAGADAIYTQL
FFNNQHFYRFRERCAQAGIDRPIIPGIMPITEYRRIQRIMSMCSSEFPAELVGRLEAAQD
DLEAQFEIGVEYAIAQCQELIDAGVPGMHFYVLNRSQACKRIFDALGWHESEA
>A0A6Y4CWG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLICIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAKADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2E3TN25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiritimatiellaceae bacterium|TrEMBL
MKLIDKIKIKPMIIDGAMGTVIYERGVFINSCYEHLSITDPELILNIHKEYVNAGVDIIE
ANTFGANRIKLEAFGLHDQLEKINKKAVQLAKEAVAEKDVSVVASIGPCLKSNQQFNQKH
TQQLREVFDEQMKVIANEGIEAFFLETFTHSKEIIIAAEIAKKYDVSVFASVTVGKDGET
RGGERIENIITDLDKSEFIDALGINCGIGPAAALSIAERSLPLTSKPFTVMANAGLPQEV
DGRLIYMTTPEYFTEYAKKLIEIGVQGVGGCCGTTPEHIKTMSKQIKSLSGVKTHIXVKT
YHEKNEFTSEITKVEDKCNFAKKLISGXKVSXXEITPPRSIXLTPMLXKCSECKKANIDA
INIPDGPRASARISPMVAALAIEKEVGIETILHYCCRDRNLIGMQSDLLGGYAGGLRNYL
IITGDPPKLGDYPDSTAVFDVDAVGLTQMVNNLNHGVDIGGNIINPPTGILIGVGANPCA
IDSKRELNHYLNKINAGAEYSITQPIFDAQALLKFLDDVEKNINPIPVVAGIWPLVSLRN
AEFLKNEVPGVEVPDSILKRMSKAKTKEEGRALGIEIAREIRDEISDRVAGFQVSAPFGI
IDLALQVIKE
>A0A368LKL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio casei|TrEMBL
MSYSHAGHIDALNHNVADLAGKINVSFEFFPPSSEKMEETLWSSIYRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASRDELKEIAKDYWNNGIRDIVALRGD
LPVGGGKPDMYASDLVELLKGVADFDISVAAYPEVHPEAKNAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVNAGIDVEIIPGILPVSNYKQAKRFADMTNVRIPSWMAKQYE
GLDEDPVTRQMVGASQAIDMVRTLSREGVKDFHFYTLNRSEMTYALCHTLGVRPR
>A0A7L4TEU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. IR1|TrEMBL
MKVTEHIENAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
VMALRGDAMKDEQYFMPKAGGNDYAIDLVKQISLLNQGKYLHEVMDADNRANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFNFVERAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVGQCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASSVF
>A0A0S3KFA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus silesiacus|TrEMBL
MRTDTLFKEKTVFSYEIFPPRRTAPVDTIYHTLDRLKGQQPDFISVTLGAGGIGANLSTV
DIAQKIQDEQFLPSVAHLPAVNFSKDEIVVILEELKQKKVENVLALRGDLLPDKEPKKDF
SYANDLVAFIQEQGDFNIIGACYPETHSDAANSVEDIRNLKRKVESGTNQLISQLFFDNN
YFYTFKEKCDIATIEVPIQAGIMPVVNKKQIERMVKMSNVTLPTKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVAQGVDGIHLYTMNNPYVAQKIREATRSLFDA
>A0A3D2ENB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTDTKAAVMKLFGDFTVETTPNSAAKIPDYNVRLRNDTPIYVTFLPGSDVYETVTLAKRL
RGEGFSPIPHIAARSIQSVDMLRDILDRYVGEAGVEHVLTIAGGVDNPLGPYDSSMAVLE
SGLIDKAGIRQVSVAGHPEGSPDITDELIKDALAWKNGFAERTGAALDIVTQFAFEAEPI
IAWDKRINAEGNRLPIRIGLPGLATIKTLLGFSRAAGVGNSIKFLVKRAADVTKLMSINA
PDKQVIDLARYAAEDPKAGISGVHMYAIGGLKRTSAWSYALRDGLFAVTGKDQLKVSVDL
G
>A0ZJ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nodularia spumigena CCY9414|TrEMBL
MQDTQNPTVLNSFRRAAQAGEFLVTAEVAPPKGVDVTHMISMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQNGIEPICQMACRDRNRIGLQADLMGAHALGIRNILALTGDPVKV
GDHPHAKAVFDLESVRLLQLIRKLNQGVDDNEKPLPDGETDLFAGAAVDPQSDSWSGLQK
RFERKIEAGAQFFQSQMITDFERLEKFMDTVAVNYEKPILAGIFLLKSAKNAQFINRYVP
GVNIPQHIIDRLAQAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIAPILDLAGV
TPVTNVN
>A0A0C2AXL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. AcH 505|TrEMBL
MRALLAGGGRSYSFEFFPPKTEAGERTLWNAIRRIEPLAPSFVSVTYGAGGSSRDRTIEV
TKRIAAETTLRPVAHLTAVGHSVAELRHIVGQYADAGIRDVLALRGDPPGDPRAEWVRHP
EGFAQASELVTLIRELGDFTVGVAAFPERHPRSPDWDSDVRHFVAKCRAGADYAITQMFF
DVDDYLRLRDRIAATGCTTPIIPEIMPATDARQIKRFAELSDARFPAELAERLEAARGDA
EAGHRIGVEYATAMAERLLAEGAPGLHYITLNRSTATLEIHQNLGVSAPRGNAQVLAPR
>A0A2D6TRH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MQQTTISFEFFPPKNATGEVRLSKALQQLTALNPEFITMTSGAGGSGHDNAFDTLTNIQA
NYPHLSTAAHITFITETKDSIRQTADYLWQNNIRALVALRGDIPPNEDINTYIDENHYRY
TNEFIAGLKELHDFDIMVGTYPEKHPDSPDLSQDLMALKRKQDAGASRALTQFFFDNSVY
YDFIEHAEKSGITIPICPGILPVRNYERLLNFAKNCQATIPSNIIDGFEKYKSAPDDLRR
FAEEILNAQVSDLMHNKVPHIHFYALNSAEMLDESLFKNVSD
>A0A381DGU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sputorum biovar sputorum|TrEMBL
MTLSFEIFPPRKNDNVEKIYDTLEALKDLDPDFISVTFGAAGSKNSTNTLDIATLVKDKY
KTKSIVHLPCIHKNKDEILQILQECKKRGLNDILALRGDEVENEKVSEDFSYASDLVKFI
KQNGNFTIYGACYPEKHKNSKDFVEDIKNLKIKVDAGVSTLLTQLFFDNEDFYKFRQNCD
LANINAKICAGIMPVTNKRQILKITSLCGAKIPPKFVRILDKYQDDEKAMFDAGIAYAID
QIVDLVTYGVDGIHLYTMNNAKVAIKIYDAIKSLFQREIK
>A0A523FMP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MNTQTSIAEATAFSLLDWQPDDLRISFEFFPPKTAEMEEQLWQVIRRLEPLQPDFVSVTY
GAGGTTRERTHRTVTRILKETSLTPAAHLTCVGADRDEIDAIAQQYWDDGVKHIVALRGD
PPEGQTHYEPYPGGYDYAEDLVKGLGNIGNFDISVAAYPDVHPEASNSASDLDFLKRKVD
AGANRVITQYFFEPETYLRFRDKAAAAGINVPIVAGIMPVTNFKQVQRFSAGCGAVVPDW
LEHHFDGLDDDMATRRLVASAIVAEQCRQLIAADVQDFHFYTLNRAELTAGICHLLGIRP
QTGHNLNEGQGQ
>A0A537SHP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTAEPRASRFVRPRGDGEARRIRVSFEFFPPKTEEMEKTLWESITRLAPLEPNFVSVTYG
AGGSTRERTHSTVKRILAETALAPAAHLTCVAATREEIDTVIRSYCGAGVRHIVALRGDP
IGGIDERYAPHPGGYRNAADLVAGIKRLSEVEVSVSAYPEKHPDSPTVEADLDMLAAKVD
AGAARAITQFFFENDLYFRYLDRVRARGIDVPVVPGILAVQNFKQTKAFAARCGASVPDW
LAERFDGLDDDAATRKLIAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAVCHLLGLRP
SQAAGNGLGLLPLPGGERVGVRGVG
>A0A2K4FHN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MPBD7-1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLAQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGEHFHVEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A537RJ59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MQNSARGLLGADPVSDFDAGPPRISFEFFPPKTQEMEERLWASIKRLEPLRPRFVSVTYG
AGGSTRERTHSTVRRIRQETALEPAAHLTCVAAAREEIDAVARDYWEVGIRHIVALRGDP
PGGIGAGYAPHPGGYAYAADLVAGLKKVADFEISVAAYPETHPSARSPGHDLDNLKAKLD
AGASRAITQFFFDADVFLRFRDRARAAGIEIPIVPGILPVTNFAQLKRMAAACGASIARR
ARPQTRRGGCLVPSRFAFTPHPSFPRKREPRAAGFQADAPCSSQGQALDPRFRGGDKYKK
SHAYTRQ
>A0A170WZN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. F-3|TrEMBL
MRDILATGKPTYSFEFSAPRTPKGQRNLWNALRRVEAVAPDFVSVTYGAGGSTREGTVKE
TEQIAADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLALRGDPPGDPMGEWVPHP
QGLMYAAELVRLIKESGDFCVGVAAFPEMHPRSADWETDVRHFVDKCRAGADYAITQMFF
QPESYLRLRDRVAAAGCDTPIIPEVMPVTSVRMLERLPLLSNATIPDGLKERILTAKDDP
AAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHTPQA
>A0A1I7I3V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. 174MFSha1.1|TrEMBL
MYPTAFRPSRESRRPIRVSFEFFPPKSPEMEATLWSSIERLAPLGPSFVSVTYGAGGSTR
ERTHNTVSRLVRETDLKPAAHLTCVAATKGEVDDVVRAYHEAGVRHIVALRGDPAEGVGT
AYTAHPGGYERSCDLVAGIKRIGDFEVSVSAYPERHPEAVSLDQDLDALKAKVDCGADRA
ITQFFFDNDLFFRYLDRVQSRGIDIPIIPGILPVQNFKQAANFARRTGASVPDWLAARFE
GLEDDVATRKLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRAAPVAAE
KAAA
>I9T4R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides salyersiae CL02T12C01|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLCRDIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESIFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDSDIYWLKKKVEAGAEYAVTQLFYDNQRYFEFVERVRKEGIDIPIIPGIKP
FKKASQLSMIPKTFKVDLPDDLVKETLKCKNDAEVQQVGVEWCIKQCRELMAHGVPSIHF
YSIGAVDSIKEVAKEIY
>A0A6C8G327|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Infantis str. SARB27|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7Y4M1I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium archetypum|TrEMBL
MTEVTPPAFGGHRTLHSPKISFEFFPPKTEEMERSLWETINRLAPLAPNFVSVTYGAGGS
TRERTHSTIARILKETSLVPAAHLTCVGAPKGEIDEVVARYHEIGVRHIVALRGDPTTGI
GTAYHAHPEGYQSSPDLIEGIKKHYPDIEISVSAYPEKHPESPTIDADIDTLKAKVDAGA
ARAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARGFVTRAGTTVPGWLAD
KFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A6G2X478|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8375|TrEMBL
MALGTASTRTDRAHTVRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVRHPDGVGYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVA
KCRAGADFAITQMFFYPEDYFRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A4VXA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis (strain 05ZYH33)|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINKNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A2D7W8T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MDVASLYRNAPGGLPFSLEILPPNXGLGLNXIHDFFNNLHXWLPAFVSVTYHQAHKIDII
DDNGQMEQIWNRKKPGTLGVCAMLKFQYGLNVIPHVICGGFSKFXSEDFLVDLDYLGLKH
ILALRGDPNKTETQFNPHPQGYAYAXELVEQIVDMNAGKYVEDVKEARPTXFQXGVAGYP
EVHAEAMNLHDDVTNLKRKITSGASFVITQMFFDNTCFFXFDKICREMDIHVPLIPGIKV
ITSKRQLEVLPEIFGTKLPKKLVDDVMACETDEEVCQVGIAHAVNQTKELLEYGXVGVHF
FTMNNSQVFNXVLQQFQE
>A0A7T1MP13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. CBW1108|TrEMBL
MISISRSEISGRTGPRGPAVERSESIRPGRRLPPSVGRAKTNNGCCDERTGLQLQKALAS
GASALTAEVMPPRGGDPARVLAAAESLRGWVHAVNVTDGSRAVMRMSSLAVCRLLLDAGI
EPVLQLACRDRNRIALQADLLGAQALGIRNLLCLTGDPVRAGDQPDARPVNELEAVRLLQ
LVRQFNAGQDPVQGQLPDGPTDLFAGAAADPQSSSWSGLKSRLVRKKEAGARFVQTQMVM
DGEALKRFVGEIAAPLQLPVLAGVFLLKSARNAAFINRVVPGAQIPQVVIDRLAAAADPA
AEGVAIAADQVAAYLQIAQGVHLMAIKAEERIPEILRQAGLTASL
>A0A534JP23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MRRPFRTSLASTPLVLEIVPPSRRASEKAISTLVDRVRDAVASLGNLDGLNLPQVLDENH
QGQPFLRNMDPRDFVQRLGSDLGVDPIVNNVVAHVPSANAFRRWARESLDKSGLRSFVLV
GGTSSRVRYPGPTVLEANRILRSAAEGHNEVALGNITIPDRENEVDRLIEKTRAGCDFFT
TQVLFEAEPMATVVRAYGKRCAAQGMKPATVLLSFAPVSDYQDLEFLAWLGASVTPRTEE
ALSGSEEKALGRSSIELARTLWSHLLAAALQSRPAVPLGVNIEEVSLHNFDLAVQMAREF
PSWRDAKSPRADHV
>A0A0F8XWW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lokiarchaeum sp. (strain GC14_75)|TrEMBL
MVKRPAYSNLIKAIQDGHFVFTGELEPKKILNLDKIIHSAKEMKKTGRIIAANVTDGPQG
DAYMSSMVPSYMVQEKANIEAVWQVTVRDRNRIALFGDVIAGAVLGLKNILTLTGDHTAL
GDHKKSRPVYDIDSTQFAEMLSMMIDDGTDYEGNEIKGGKIEMNFGCVANPNSDPREPEI
LKVGRKVEQGIDFIQTQTAFDIDQAKEFLKELEQFNVPVLLGVFPLKSHGIAWYFDNYIP
GVSVPKDLLKSLKTAEKENKGNKPGKYAAIDKINIEFFKPFIEEIKKTTKAAGIHCMAVE
YERLFESLLGGFPEYVK
>A0A7C5FER3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MTGQARELNNLEKKLCENRFVVTAELGPPKGADPEYVREHARILKGYADAVNVTDNQRAV
VRLSSLASSLIMMQEGLEPIMQMTCRDRNRIALQSDLLGACSLGIKNVLCLTGDHQSMGD
HKGAKNVYDLDSIQLLSIIKKMRDEKKDFGGKELTKPPNVFIGAAANPFADPFEFRVIRL
EKKANAGAQFIQTQAVFDIPRFEKFMELVRSRKLDNRLHIIAGVLPIKGPKMLRNMKENV
AGVSIPDSLIQRMEMASDKKEEGIKIALETIETIRKIKGVKGIHIMAVAWEDVIPRIVKE
SGLIDVISQ
>A0A1H1LSV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sandarakinum|TrEMBL
MEASTATNVLDDFSLEMTGKDVPGLQQAAHAIPQGTRVNITFLGNENLEMRLEAAKEVLE
LGFVPVPHISARRLKSETELREFLDALQQAGASDHVFVVGGDPATPEGPYPDSLSVIRTG
ILQEYGVAEVGIAGYPEGHPDISTQTLWEHMSAKSASLAEQGLGQVVLTQFAFDAEAVVA
WVHEVRGHGVEADIRIGTPGPAGIKRLLGYARRFGVGTSAGIAKKYGFSLTNLLGTAGPD
RFLTDLSSYDSITSATSGVKTHFYTFGGLAATAEWVQDFTAQA
>A0A4S4AKY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium composti|TrEMBL
MTSARPPQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
GAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNGKFLSGRKLTTPPQ
VFLGAAINPFAPPYDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQRVRDLGYTEKVF
ILCGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAEDQKKEGKQLCIDIINEVKEIPG
VSGVHVMAYRQEEYVAEIVDESGVLKGRRPWIREVRADDALVAERLGRLLHDDITETQVD
MVKSAH
>A0A1V9GRW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas phaseoli pv. syngonii LMG 9055|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRLLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A2U3C2Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ICBB 8177|TrEMBL
MALGTPSTRTDRAVTIRELLASGERSYSFEFAAPKTEKGERTLWNAIRRIEMVGPTFVSV
TYGAGGSSREGTVRATDRIVSDTTLTPCAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWIPHPQGLTYAAELVRLIKESGDFCVGVAAFTETHPRSTDPATDARHFVD
KCRAGADFAITQMFFDPEAYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFSQLGNAPF
PPELAERILAVRDDPVAVREIGVEFATEMCRRLMAEDIPGLHFITLNHSTASLEIYENLG
LHQRS
>A0A2M8WYV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. 69|TrEMBL
MNAANAQGTGFPVSFEFFPPKTPEGADKLRVARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVGAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPESDLKAYVAKVQAGADSAITQYFYNSD
AYFRFVEDAQRLGAGVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSTATLEICRRLGI
>A0A162JLB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium rileyi (strain RCEF 4871)|TrEMBL
MHIKDMLVEAEKGGQPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLDKVNDALQRAYKAGCTNILALRGDPPRAQEK
WTAAEGGFQYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGKVRERGINVPILPGIMPIATYASFLRRAKHMQCKVPDHWMTAL
EPVKNDDVAVREIGKSLVAEMCRKLLASGIHHLHFYTMNLAQATRMVLEELTWAPCAERP
LQHALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPNTVQDIANIFVKYLNQELDSLPWSEAPLTGEANAIKANLVE
LNKRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPGSIFTEMVKRVEDKP
TLTYYAVTKDGDLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
AHCFESETPSRILLDHIVNEWYLMNVVNNDFHDNQAIFDLFEGLEVRGLDTPLTT
>A0A451DDW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MIYIIKDSNKPYNYESYHLKNKIRVSFEVFPPQNSKLEEKLLRSICVLNQIHPDFFSVTN
SIHAKNRDKTFFVVQKIRALTKVNVFAHFTTIGLNKSEIQNIARKYWDYGIKHIIALRGD
LPDQYSQKIIYANDLIKLLQSIHDFEILVAAYPELHPESCNIQEDLINLKNKADLGIKKA
ITQFFFSVEKFLRFRDNCINMGLPITIIPGILPILNINQLKRFSCLTNVYIPKWIFSAFD
EYKDDLNQCMDLSVRIAVNLIISLYNEGVTNFHLYTLNQSTLSFKICHQLGLI
>A0A136PJK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora rosaria|TrEMBL
MALGLPSVLPPQPAIGELIRAGQTFSFEFFPPKTAEGERLLWQAIRELESLRPSFVSITY
GAGGSTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVRGD
PPGDPAGEWVRHPEGVGYAEDLVRVVREAGDFSVGVAAFPYKHPRSPDVHSDTEHFVRKC
RAGAEFAITQMFFDADEYLRLRDRVAAAGCDTPILAGVMPVTQMRTIERSVQLSGAPFPT
ALAEQFDRVRDDPEAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLRVG
ARV
>A0A2R7Q4I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. HMWF015|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A062MXD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 796380-1375|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A6L8ZAP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPN
>A0A7C1JJB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilinea aerophila|TrEMBL
MNDHPFLQRLAERPLLIDGAMGTMLYARGASSEQCLEHLVVSRPTWVREIHQAYANAGAD
ILKTHTFGANRVRLADYGLAERVRDLNFRAVKLVRDVREVSGRAIFIAGDVGPLGKRLQP
EGPLSAAEAEEAFREQISVLWEAGADLLLFETFIDLQELELAVRTARKVCDLPIVASMTF
AEDGLTLVGHTPEEAVRRLHAAGADVVGVNCSVGPAAMAQTLEQMHTAAPDARLIIMPNA
GFPERVEGRFYYPASPEYFARQTALFLTQGARIVGGCCGTTPMHIRAMRAALDEHLTVQV
GTPRPTLVVQEEPPPAVKADYGVTDEVEPTELLRKLRAGKFVISVEVDPPRSFSAEKQIE
GARHAMKMGADAVNVADSPMARVRMSALALCVQIQQQVGIETIVHFTTRDRSLMGLQADL
IGARALGVRNILALTGDPPTLGDNKQSTAVYDVDSIGLVRIISRFNEGVDVGGQDMGQKG
GFTIAVACDPTRADLVQEVDRFHQKVIGGAHFTMTQPIFDPQLWLNFVRLYEERHGKFPV
PVLIGVLPLQGHKHATFLHNEVPGITLSEEALERMRKAGPNGRQEGVKMAQELLLELKEL
PYVQGVYLMPSFGRYETACQVLEVL
>A0A7X8MTL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium pollutisoli|TrEMBL
MNAAAPHHSAKRRFSASAPLDTFDPEESRQVRVPERTSLSFEVMPPRHDADEASIDALLA
TLQSYNPDYISVTSSRNSGWLEGTARFIEKITASTRIPTLAHLACTAGTREELIGWINRL
MDSGVRGLLALRGDLAEGQTEMPAGYLPHATDLINLIQSIEDDQVARFGAGRLAIGVAAY
PSGHEESANMDEDIDVLLTKQRLGADFAITQLFFDAEDYLRFAERARLAGVRIPLIPGIM
PMTSVARLHRMGQLSGLTVPDRLIRRLEAAGPESEYQTGLDLTAELAQTILAAGAGGMHV
YTFNRPDTTTELLDRIGIVPPTTG
>A0A7V4G8Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans|TrEMBL
MEPKTPSKLEKIMAAGHFGVTSEVGPPRGCDGAEIEHKGHLIKDYVDAVNVTDNQTSVVR
LCSLASCIRLKQMGIEPILQMTTRDRNRIAMQSDILGAASFGIHNMLCLTGDHQTFGDHP
MSANVFDLDSVQLIQTVKLMRDEGKLLSGFEMKVRPQIFIGAAENPFAGPNVELRALRLG
KKIAAGVEFIQTQCIYNMATFKEFMKQAVDRGLTEKVAILAGITPMKNVGMARYMQKRVP
GIDVPEEIVKRIGGVPKDKQAEEGLALAIEQIQELKEVPGIRGFHIMAIEWEEQVPGIVE
RAGLYPRPSLN
>A0A8G8PLK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLKAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6G4JZH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
IAKRLEGFGDDRESIRAFGLDVVTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A826SNL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFANMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A2H0QES3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium CG11_big_fil_rev_8_21_14_0_20_44_7|TrEMBL
MGDNLPNKSPKFSFEFFPPKSDEMEKKLWEAITKLESLNPEFVSVTYGAGGSTRERTHAT
VKRIGSETSLKAAAHLTCVNASRAEIDEIAQQYWDSGIRHIVALRGDMPDAGGAYIPHPE
GYKYAADLVEGLKKIADFEISVAGYPESHPEAISAEDDFIHLKEKVDAGATRVITQFFFN
ADDYFRFLERARKIGISVPIIPGILPIANFAQATKFSKMCGAKIPERLMKLYEGADENPQ
YRNMISVITTTELCHKLMEGGVEQFHFYTLNRYELVQAVCGYLKS
>A0A4Y4M7J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. ON_d1|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEEQVSDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>C4FKN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurihydrogenibium yellowstonense SS-5|TrEMBL
MKIIDKLKNTKISISFEFFPPKTEEAEKTLFETISNLQPLNPTFVSVTYGAGGSTREKTR
DIVKKIHEETNLTVMAHLTCIGHSKQEILSILDDYKKIGIENILALRGDMPLNFEKTDIP
SDGCKHASELVSLIRENYKDYFCIAVASYPEGHPESSNLEREILYFKKKVEAGADFSITQ
MFFDNSYFYEFLEKCEKAGINIPIIPGIMPITNFNQIKKFASLCGATIPEEVVQKFEKYA
DNPEETKKIGIEFATLQCIDLIKHGAKGLHFYTLNKSDATIKIYENIKDYLA
>A0A7W9XAK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. X5P1|TrEMBL
MKITEHITKAAGKTLFSFELLPPVKGRSIQEIYDAIDPLMEFNPPFIDVTYHREDYIYKK
HESGLLEKVSYRKRPGTVAICAAIINRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADPSFVPTPGGHAYACELLEQVTNMNKGKYLYEDHDVVNADFCIGIAGYP
EKHFESPNLKTDFRYLKKKVDMGANFIVTQMFYDNNKYKEFVKLCRENGINVPIIPGLKP
ITSSKQLINLPKIFHIDIPEDLADAVQACKSEKDVKDVGIEWMINQCKELIEFGAPVLHF
YTMSNPGPTKRIAEAIF
>A0A839Z0V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomicrobium lutaoense|TrEMBL
MNLTSTPAPAPLFERCHGDIDVSFEFFPPRSEAMQERLWQSIGRLAPLEPRFVSVTYGAG
GSTRERTHSTVKRILEETDLTPAAHLTCVDASREEVQEVARDYWDAGVRHIVALRGDPPD
GQPFSAHPDGYANAAELVAGLKEVADFDISVAAYPEGHPEARSADADLDHLLRKIDAGAE
RAITQFFFSADAFFRLRDALAARGRNIELVPGVLPVTNVERTREFARKCGSAIPDWLDQK
FEGLDALPDARRLVAATVATEMCGRLYAGGVRHFHFYTLNRASLSWTICHMLGVKG
>A0A6J4XHW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius sp. associated proteobacterium Delta 1|TrEMBL
MTEDNFTVTIEVVPPTGPDAAPLLAALEPLVDLAFDGFSVATNPVAKPHMSAMALCALLQ
KKTGKPAVLHCTTRDHNRLSLQGMLWGARALGIETVLIATGDFIALGDRAHTTSVRDLDV
FDLVRMAREAELRTGVVFDTHPESNGLEKAVRRLASKVEAGAHFAVTQPVYDEASATQLI
EATQHLKIPIILGILPLRTPRHAEFLHRKVAGIAVPEQVRNRMQGADDPVAEGVANAGEM
LAIARKHFAGACLMPPFDHYEVLFDILAD
>A0A8I0W2M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSAERFAAMETILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQMQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSRQAAPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAKSK
AFALARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVYASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPMWATRLGAQVLHKVEHAVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAMRQTELLTERLIPCIELETRHRSSWPQWFQAQTP
RQFSSQPAPRTQPES
>A0A7T1AZT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus lloydii|TrEMBL
MTQQLLDKLKNNILVADGAMGTILYSEGLDTCPEAYNLSHPERVERIHRTYIEAGADVIQ
TNTYGANFEKLKAFGLEHKVKDIHQAAVKIAKKAASKDTFILGTVGGFRGVRQEELSLSA
ILYHTEIQVDTLIEEGVDGLLFETYYDLEELTNIIQATRNKYDIPIIAQLTASNTNYLRD
GSKINDALQQVIDSGADVVGLNCHHGPHHMQQTFSHIELPEHAYLSCYPNASLLDLNNSE
FKYSDNAEYFGKVAQKLINEGVRLIGGCCGTTPEHIHYIKSSIKDLTPIHNKKVVPITKQ
NAAAKSTTSKENLTTKVKRGATIIVELDTPKHLDTEKFFDNIQKLDDAEIDAVTLADNSL
ATVRISNVAAASIIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLLGVNEILTITGDPSK
VGNLPGAMNVFDVNSKGLTEIAKRFNQGMNTDGDALKKKTNFNIAGAFDPNVRKLDGAIR
RLEKKIDSGMDYFITQPVYSKDKIKTVYEATKHLDVPFFIGIMPITSYNNALFLHNEVPG
IKLSEDILTRFEAVKDDRDKTRELSIEICKELIDTVHEYFNGLYLITPFQRADLSLELAA
YSKSITSNSQEAIL
>A0A2D1TCU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKEELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEIDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLAIWNNLKLPR
>N8Y5N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter schindleri NIPH 900|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQRNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHKIAGIVITPHMLRVLAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVET
KKELVPQLAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A1W9QXP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium 4484_65|TrEMBL
MFEKFCDILCLEKRFITVEINPPHGASIDGLIEDIKKHNLQDKVTGFSCTDNPLAKLKMS
GVLSAIKVQQEFGKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKFSDQPD
VKGVLERDSTLLLSIIHHLNKGVDYSNKALIPAPKP
>A0A2S3XAZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKDELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGNHFHLEVAAYPEMHPQARNFEADLGNFVHKVKAGADSAITQYFFNADSYFY
FVERAQKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLAIWNNLKLPR
>A0A1H2HDP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula phenolica|TrEMBL
MNALNTESRLEKVLKAGHIGVTSECGPPRGSDAQEVKKKGLLIKDYVDAVNVTDNQTAMT
RMSSLAACIHLKLMGIEPVLQMVTRDKNRVALQSDILGAASFDIPNMLCLSGDHQSFGDC
AQGQNVHDLDSMQLVQTVRYMRDEGKFLGGDKIKRPPKMFVGAAANPFADPFEIRVPRLA
KKIACGAEFIQTQCIYNLDKFKEWIRLAVERGLTEKTFIMAGMTPMKSVGMAKYMKNRVP
GMDVPDEIIKRLAGVAKDKQAQEGIDICVEHIQELKEVTGVSGFHIMAIEWEEKVPEIVE
RAGLYPRPEL
>A0A1V1W920|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. PD653|TrEMBL
MSITPRGGASSAVGLLHDFSLEITGKDAGALRSAGAAIPAGTRVHVTYLAQEDLSLRLAA
ARTVREVGLVAVPHVSARRLRSRAEVDEFVGALRADGNAEHLFLVAGDPRTPEGPYADTL
AVIESGVLEDNDVRQVGVTGYPEGHPYIPDDVLWRSLEQKMSALAERAIGASVTTQFGFD
ADQVLSWVEKVRQRGVTVPVGVGVPGPAGARRLLAYAARCGVGTSASIAKKYGLSLSNLM
GSAGPDRFLDALAARYDERRHGDLRLHFYTFGGVDATAAWTRRFANSAP
>A0A532U383|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium B3_Chlor|TrEMBL
MKLTQLFADGRFVITSEAGPPKGVDTTKMLEEVALLRGRVDAFNVTDQQSSVMRLGSLAA
SHLLKQQGAEPIFQLTCRDRNRIALQSDLLSAYALGIENVLCLTGDYVSLGDHPGAKPVF
DLDSVSLIHTIKTLCEGHDLAGNELMGKPDFCIGAVVSPGADPIEPQIIKMENKIEAGAQ
FFQTQAVYDLDQFSDFMKQVKHLRVPILGGIILLKSAGMARFMNRNVAGVYVPDNLIDKM
DESTDKVATSIEIAAELIKAIKDVCQGVHIMALGWEKWVPDLLREAGLWDRLSSS
>A0A4D4IZQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agarivorans sp. Toyoura001|TrEMBL
MGFHNAQQIETLNQSLSELNRDINVSFEFFPPTTETMEQTLWSSIERLQTLKPKFVSVTY
GANSGTRDRTHKVIKAIKDRTGLAAAPHLTCIDSTPDELRQIARDYWNSGIKDIVALRGD
LPEGSAKPQMYASDLVALLKEEADFDISVAAYPEVHPEAKSAQADLLALKRKMDAGANRA
ITQFFFDVESYLRFRDRCAAIGIEGEIVPGILPVSNYKTLKKFASFANVKVPSWLHGQFA
GLDNDQTTRNLVGASVAIEMVKVLSREGVKDFHFYTLNRSELSYAICHTLGVRPAEAIPA
>A0A3G2RZP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malassezia restricta CBS 7877|TrEMBL
MCEEGQRRMAARVDEKLAGNDAYLWSLEFFPPRTALGLANLLARIWRMSTALQPGWVHVT
WGTGGSTCHASLELAARVQNGVYDPAEDYTKVTEPRSGACDVCLHLTCTNVERSCLDATL
DDAKRFGIRNILALRGDPPRNEEYWVATDQRLQNATDLVKYIRERHGDYFCIGVAGHPEG
LKQGIDCDIPHDLRVLKAKQDAGARFILTQFFYDVDKFVRWVQACRDAGITIPIIPGVMP
IQNYTIFRRMSNLCGVHAPEHVLAQLESIKLDDAKVKDEGIQLSIDMIRAVRKQTGLKTF
HIYTLNLEKSATCVIKELSEVAQAGQAAQSLSNSMTWDEFPNGRYTDTRSPAYGEIDGYG
ASLKVPPEEAVRLWGVPVDEDDIASIFTRFIEGQLPCMPWCDIPVWNETMEVLPSLVRLN
APRSKGGKNWWTVGSQPAVDGCDSTDPTYGFGPQGGYIFQKAFVELFLTPEDKDALVRHI
EASPSPVTYFAGKWDPDSFQTNLERDGLNTVTWGVFPGKEVAQSTIIEEPSFRAWCDEAF
AIWREWELLFPPKSATRSLLRKIHDERWLVTVVHHDYKHPDALWKLLDQV
>A0A560D8R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium stylosanthis|TrEMBL
MTDLTTPATADRHDGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRAEIDEIVDRYHEVGVRHIVGLRGDPAG
GIGTPYSSHPDGYQSSAELVAGIKKRHADIEVSVSAYPEKHPEARDFDDDIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A6H0Y5E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peltaster fructicola|TrEMBL
MVKITDKIAALPQDANYFSLEFFPPKTQQGFSNLHARLSRMAQTLRPLFVNITWGAGGST
SEKSLALAELTQRLGLTTCLHLTCTNMSRKLVDQALEQAKSLGVRNILALRGDPPRSDEY
RDDSDPNAAEDDSNKDFTWAVDLVKYIRQRYGDYFCVGVAGYPEGHADQSHPEHQSVEHD
LSYLVDKTQAGADFIMTQLFYDMEAYQKYEKTLREHESGAFKTITIVPGLMPVQSYQILK
RTTKLSHAKLPAHVLARFDAVKGDDEAVKRVGVDVLCEYVETLRKTPSPGPRGFHFYTLN
LEKAVAQILERTRLVPSHATNGVAVNHDAVVAEAEADGFVLIDGSQKSTRSPSSNVPRNK
IIVPRNRRASSSSERTSVYETTEEDIKALREQSKRTHSQALAVSEGEGNLGREATWDDFP
NGRWGDARSPAYGEIDGYGVSLHVSIAEALRLWGSPVTIADISAIFVRHLEGEIQSVPWS
EEGLSSETLVIKEQLLTLTKKGWWTIASQPAVSGVPSTDKTFGWGPKNGFVFQKPFVEFF
LPAADWKRLQPALDADEQITYFGGNAAGDFASSDEESVNPVTWGAFAGKEIVTPTIIEAE
SFKSWLEEAFGIWSEWQRVYRPGSDTSKLLEKVRKDYWLVNVIHHGFLEDGALWKQLVLS
>A0A7Y7TFM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium|TrEMBL
MNILERLKHEILTGDGAVGTMLYARGVSLDSNFEHLNLVRPALVRELADEYVSAGAQVIE
TNTFGANYTKLAAIGLGHKVVEINLTGARIARQAADRGRDVLVAGSVGPLVRIKGEEREP
GEAEMVEIFRLQCQALAEGGVDLFLLETFSSLPQLVAAVRAARSTGLEVCASMAFLEGGR
SSDGSTVERFCAAVELAGADLVGANCGAGPLELLKVVQRLSAVTDKPIVAYANSGFPEYR
GGRYIYRATPDYFASMAQEMVAAGAGLVGGCCGTTPEHIAAVARALAGCKPVVRSRPAGV
SVSEPEQPWRPDSGSFLDDWGRRTVITVELDPPKGLDCSRIIEGCRRLKLAGADAINLAE
NPLARPRMGNIALGSLIQQQVGIRVIIHITGRDRNLIGMQSDLLGASLLGIRSVLAVTGD
PASMGDHAGATSVFDLHSLTLIKLLSDLNRGVNAVGNPIGGGAGFTIGAAFNPNTKDMVH
QAGRLRKKVANGAVFAQTQPIYDPALFFEALKQTADCRIPLIPGIMPLVSERNAEYLHNE
VPGISIPESIRARMRGLEKEAGVREGLAIAREFIDATFTSAGGYYLMPPFGKVELALELI
NHIHTKEREHLCTESLS
>A0A840XWB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas pecuniae|TrEMBL
MNEMSPPAKTLQSWLSGPRVDALPSLTAMPAPLLSFEFFPPRTEALENQLWACVKRLEPL
RPRFVSVTYGAGGTTQARTHATVTRILRETSLTPAAHLTCVGATREEVDEVARGYWEAGV
RHIVALRGDPPAGQSGYEPHPGGYAYAADLVAGLKRIADFEISVAAYPEVHPTATSPDED
LDNLKRKIDAGATRAITQYFFDAPTFLRFIDRAHAAGITVPIVPGILPVTNFAQVAKFSA
MCGAKVPDWMGTLFDGLDEDAETRRMVAAVVAAEQVRLLQANGVDEFHFYTLNRPDLTYA
IAHILGARPQG
>A0A7K7IN96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loxia curvirostra|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDHMGAGGPLFVDVTWHPAGDPGSDKETSSMIIAYTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVHGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVYAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVRALLKVLKKYELRVNY
HIVNVKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6H0Y173|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peltaster fructicola|TrEMBL
MHISKKLAAAHSKGQQTYSFEYFPPKTAQGVQNLYDRIDRMHGLGPAFIDITWGAGGRLS
QLTCEMVKVAQSAYGLETCMHLTCTDMEKSKIDDALADAFNAGCSNILALRGDPPREKEK
WEAVEGGFRYAEDLIKYIKSKYNDHFDIGVAGYPEGCDDGTTAEDHIPHLKAKVDAGGTF
IVTQMCYDADIFIDWVKKVRAAGVPEDVLIIPGIMPIHTHASFLRRANWTKCNVPQSWHD
RLEPVKNDDEAVREVGKDLVAEFCRRLLDIGIMHLHFYTMNLATASRMVLEELNLTPATD
AHNPDLKPLPWRQSLGRNRREENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFG
ELDAYGIGLKGTNEANRKIWGEPKTIKELSELFKGYMSGKVESLPWSENPINTEASVLVQ
DLIDLNGRGLLTINSQPPVDGAKSTHPDYGWGPRNGYVYQKAYLEVLVHPALIDQLVARL
EKDADATYYAVNKSGELRTNAPEDGSPNAVTWGVFPGKEIVQPTIVEMVSFLAWRDEFYY
LGSQWAKCYEENSESKRLIQGVMDGWYLVNIVHNDFRNNRAIFPFFEGLSALELESKQTN
GVAHVNGDVQVNGVH
>A0A2U3MPL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc carnosum|TrEMBL
MTKISEIYHTKPAPVLSFEIFPPKKEGDIESLYQTLNDVDPLALGVDYISVTYGAGGSGN
NIKTRDLAQYIQEHFGVTALHHLTGINQTPEVLQDQLADIKQAGIENILALRGDLPDADY
VNTYYPYAKDLIHDIKQFNQFNIGAAIYPEGHVDNPVTGISVAGVKEKVVSGTDFLISQF
FFENDVYYNMQDALKSNYIKVPVSAGVMPIINKAQVERMTYMIGSSLPSRLVKIIHKYEN
QPDSLKQAGIEYALEQIHDLLNHGVDGIHLYAMNRPSVLKSMLPVINQDIQSKSLDFP
>A0A346N5W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solimonas sp. K1W22B-7|TrEMBL
MAQEIHFSFELFPPRTPEGWQKLPNLVQKLASVRPAFFSVTHGAGGSDQHGTYEAIMQVV
EHSGIEAAPHLTCVGSTRANVAALLARYREAGVRRIVALRGDLPPGHDSAGAPGEFHYAN
ELVSFIREQHGEHFRIEVAAYPEMHPQGASPAADFENFRRKAEAGAHAAITQYFFNADAY
FDFVNRCEQAGLNIPVIAGIMPITNFAQLARFSAVCGAEIPRWIRLRLEQLQDDKPALLD
FGLDVITQLSRTLLDNGAPGLHFYTLNQSEPTLRLWKNLALPVPLAA
>A0A4Y9NN44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. CT_GayMR20|TrEMBL
MSVNATVRELLATDQPTWSFEFFPTKTPQGEAQLWMALRELERLQPSFVSVTYGAGGSTR
EGTLAVTERIAHETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNMLALRGDPPGADPQ
AEWVPHPEGLEFASELVELIKTMGDFCVGVAAFPERHPRSPDFETDVEMFVNKCRSGADF
AITQMFFRAEDYLRLRDRVAEHGCDVPILAGVMPVTNARQITRIVELSGQAFPTELADRF
AELDGETPEAKAAVHAYGVEVATELCRTLLDEGVPGIHFITMNRSTATREVHANLAQLPA
TS
>W0IFC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii WSM1689|TrEMBL
MALKNKARGRNEIRVSFEFFPPKSEEMEGQLWHAVGQLQDWDPDFVSVTYGAGGTTKAPT
LSTVTRLLSQTPLATASHLTCVGATQEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQ
PHPGGYANAAELVAGLKEVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQ
FFFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFD
DKPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRRQTKSAGAA
A
>A0A3S1QQZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.005.03.2.1|TrEMBL
QFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILVGVGPLASAKTAKWIRSNVPGIHIPDS
VIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSGVHVMAYRQEEYVAEIVDESGVLKGRQ
PWKREIRRDDQLVADRLDSILHDDITETQVDMVKTAH
>A0A8G0PPU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MRKQTFSVEIEANPGDLRQMKHYLHKWKPDFVSISNLSRYSYEEMVQCARYIQTDLHIPV
VIHLTGLTHTKEQIKKSFNELMGLNIRNFLLVRGNIHHNMHIEDDFNYASDLIKYVNQLD
KDSQIHVIAGCYPDIHALANSLTEDIKYLKEKVDSGVDSLISLMCFDNNRIYKFLDKSRE
YDIDVPIRIGIMPITDPFKRHYLAHNNIKMPAFSEEEDNLLENGINYAVNQINDLYEHNV
NGIHLYTHNDWMVSDRVFENIKKNL
>A0A8I1X158|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecochloris sp|TrEMBL
MLVKEILSSATEPVFSFEFFPPKKHEDWDKLFHTISELIPFKPSYVSVTYGAGGSTRTRT
HDLVTRIQKETGLTVVSHLTCICSDKEEVGKVLSTYEEHGITNVLALRGDLPPDASSYEE
ATKDFPHAIDLVRFIRNNFPSMGIGVAGFPEGHPQTPNRLAEIRYLKEKVDAGADYIVTQ
LFFDNRDYFDFVERCALEGINIPIIPGIMPVTTRKGLIRMSELALGARIPASLLKQVMEA
PDDETVAEIGIEWATRQVQELIDNHIKGIHFYTLNHAEATRQIFHNISQAINE
>A0A7X9EL42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDANRDELRQIAQDYWQSGIRHIVALRGD
LPAGSGKPEMYATDLVHLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPHWMNSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEIAVPV
RA
>A0A7J5TNR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIANTIH
GEYGIPAVAHLTALYSDEAKIDEALDMFEAAGVSAVLALRGDYIDGEEPVGRFNHASDLA
AYIHDRKPDLKVFGACYPEGHYSAASLDEDIENLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGGKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGII
YASDQIADLVAHGVDGVHLYSMNHPATTRRIWHNVEPLFTVE
>A0A318YSN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus neoniger (strain CBS 115656)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDVQDPARDLPYL
IEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPQVLSKLEEVKHDDDAVKRIGVDIITDLVYGIRDLVSPGLRGFHFYTLNLEKT
VSFILERCELIPPYTEIDDSDALVDGGNLSAMDSSSYIAPNGAPIRTLASRRSSVSSIPH
NRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEEDSNGLNAETAVIQPELLTLIDKKGWWTLASQPALNGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNTDDPDPIDIN
PANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDETK
NDVWLVCVVGQEFGAGTEAGSEEEEDEKKWMWRELANSQ
>A0A266NGX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas lundensis|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLMNTARHLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVHVPAAPHLSCVGDSKSDLRGLLEQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDINNFVRKAHAGADSAITQYFFNADSYFR
FVERVQAAGVTIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EQVISEMCERLLVGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A1V6FGP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium ADurb.Bin100|TrEMBL
MAMSEAGMPQGEKDTTGVRLPLSFEFFPPKTPEGVEKLRGVRQKLYALSPQFCSVTYGAG
GSTQEGTFSAVGAILAEGVAAASHFSCVGATRTSVREQLQTLKGMGVKRLVALRGDLPSG
YGAGGEFAYASDLVAFIRAETGGDFHIEVAAYPEIHPQSRSAEADLRAYATKVRAGANSA
ITQYFYNADAYVRFVDEAARMGVDAPVVPGIMPIISSTQLMRFSDACGAEIPRWIRLRLQ
GFGDDTASIRAFGLDVVTALCEQLVRAGAPGLHFYTMNQSAATTEIVRRLGLA
>A0A520LPS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. MED-G133|TrEMBL
MATALQRAIESGQQAITAEVMPPRGGDPSHALAMAEHLRGRVHGINVTDGSRAVMRMSSL
AVCRLLLDRGLEPVLQMACRDRNRLALQADLLGAHALGIHNLLCLTGDPVRAGDQADARP
VNEFESVKLLRQVKAFNQGKDPVKAELPDGPTTLFAGCAADPHSRSWSGLQRRLQRKQEA
GARFVQTQMVMDPAALERFQVELAGPMNLPVLAGVFLLKSAKNARFINRVVPGACIPETL
IERLESADNPALEGVAIAAEQVKRYLGIVQGVHLMAIKAEERIPLVLDQAGVSSLPG
>A0A372GDE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. LHW52907|TrEMBL
MGFEVVCEVEPPTRPDLTRVRHQIGVLSPVADSFLIPDNHIGRATVSSVAVAHEVQAMGA
RGIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVYGDKPSVGGRTSELTVRAMMDEARDA
VFPGCEPFQVGVAAGLRKVPEWKRAADFMFVQVSYSVEKLLRWRESVGVDGPVYAGVMVL
ASAGMARRLAGAIPDIEIPEELVDAVERDRAAGVAAACEQVLAIRDSGAFDGVHLVPVSR
YREVAAVLERELA
>A0A162YF79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimarina aggregata|TrEMBL
MKVTEHIEKAKGKTLFSFELIPPQKGRSIQELYDNIDPLMEFNPPFIDVTTSREEFIYID
REGLLDKKLTRMRPGTLGICASITHKYNVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFIPTKGGHKYANELVTQIANMNKGQYLHEVIETNNKSNFCVGVAGYP
EKHMEAPSMDSDIRRLKEKVDAGADYVVTQMFFDNKKYFSFVEKARAAGINIPIIPGIKP
AAVKRHLQLLPQVFKLDMPDDLVRAIEGCKNNVEVREVGIEFAIQQSKELMDFGVPVLHY
YSMGKSDNIKKIASAIF
>A0A1L8CH97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MSLKDTFKNKTVFSLEVYPPKTPEGTKKLVNALTGIKRIKPDFISITLGAGGSQNNNALE
LSSMIQNDLNIPAMAHISGIYRSKKEVADFLKQLKQHNINNVLALRGDINPYETPVGDFN
HASELAEFIKTQGDFDITGACYPQKHPESIDLVDDTLHLKEKVGNGVGHLITQMVFDNQA
FYDFRQRLKLAGINVPVEVGIMPCTNCNQIKHITELSGLEMPKKFVDIMNKYANNKEAMR
DAGIAYAVDQIVDLVANGVDGIHLYTMNNTYVAKKIWEATHSLFEATSYQLQHPSLSGSD
NQ
>A0A5Q0RSH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter nosocomialis|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGIHIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A4V2LJY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 5045|TrEMBL
MTKQVPISFEFFPSKTDVGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLSTISDFN
GKGTPIAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYASDLVR
FIREHSGDHFHIEVAAYPEMHPQADHFDQDIKNFVTKVNAGANAAITQFFFNPDAYFYFV
ERIQKQGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIIKLCERLIAGGAPSLHFYTMNNTEPTRQLVTDLGLA
>R4Y9Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae subsp. rhinoscleromatis SB3432|TrEMBL
MSFFHANQREALNQCLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7X8NXU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. ERW19|TrEMBL
MNASYDQLREARTALDTPLFAGLPGDIAVSFEFFPPKTDALMAQLWDVVETLGPLQPKFV
SVTYGAGGSTRDRTHGTVARIIKEARLPAAAHLTCVDASKAEIREVAESYWEAGVRHIVA
LRGDMGAPGVPFTPHPDGYANAAELVAGLKQIAPFEISVAAYPESHPDSPSSQADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAAACGAA
IPAWMDGLFEGLDTHPASRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPKAPALEKAA
>A0A7Z0BIC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis sinuspersici|TrEMBL
MLSAPTRPVAPRNPAPRPRHIRELLDAGEPMFSFEFFPPRTPRAQERLWRAIREIEALGP
SFVSVTYGAGGSTRGMTVETTERIATDTTLLPVAHMTLVDHSVAELRHLVGRLADAGVSN
MLAVRGDPPGDPNGEWVTHPEGLTYAEELVRLIKDSGDFCVGVAAFPFKHPRSADVETDT
DYFVRKCEAGADYAITQMFFDPEDYLRLRDRVAARGCEVPIIPEVFPVVRTSFIPRSEQL
SGAPFPRDLAERFESFGDDAEAVRAFGIEYAQRMCERLLAEGAPGIHFITSNQSTATRQI
YREIAGHRSRPEAAGRP
>A0A7V8VIP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIDEILTAKGEPVFSFEFFPPRTPEGVENLWKAVEVLRGLEPDFVSVTYGAGGATRDGT
LEISSRLKNELGVETMAHLSCVGETAEGIEEMLRRIEAAGIENVLALRGDPPKGESEFIR
AEGGYSSATELARLASERFDFSLGGSCFPEVHPEAASAEADLDYLKTKVDAGARFLITQL
FFDNRVYFEFVAAARGAGIDVPIIPGVIPIGSFGQVRRICALCDATIPDELEAAMAALGG
DPEAEAMLGIAYAARQCDELLARGAPGIHFYALNRAPGTRAVLSALRAARPWELGRGAAI
EEARA
>A0A494Y615|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella endophytica|TrEMBL
MKPDLRTALALKPRVGDGAMATYLYQLGLPVGVSFEEFNLLKPDVIADVHRRYANAGAEI
IETNTYSAQHNKLSRYGLEKKTEEINAAGVAIARRAVGQEAYVVGSIGAVRGGAGKNVRT
ATVKRDFEEQVGALLAAGVDGLLLETFFDLEELSLALSIIRKKSDISVICQFAVEDAERT
HDGIPLPEAFRRLKGEGADVVGFNCRSGPNGILRAVETLPRDLGLPLSVFPNAGIPDYVD
GKVVYSATPEYFASSAIRFADAGARLIGGCCGTTPEHIAAIAKALQNYSPVQIAKAPAEA
PEVRQSIDVASDLSEPQSDIPPTELEPSIVDLVRERHTVIVELDPPRDLDIAKFMAGAQA
LKEANADALTMADNSLAVTRMSNMALAALLKERVGIRPLAHIACRDRNLIGTQSHMMGFD
ALGIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKAKFIV
GAAFNPNVKHLDKAIQRLERKISAGADYIMTQPVYDPELIVRIAEMTKHLSVPIFLGIFP
LASGRNAEYLHNEVPGIQLSDSVRERMSGLEGPVGRAEGVKIAEELLDVAMEHFNGIYLM
TPFMAYEMTVSLTEYVKKKSAHLTSVN
>A0A2V5KS37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus flagellatus|TrEMBL
MKADLRQALREGVVIGDGAMGTFLYQLGFPVGVSYEEYNIEKPDVIADVHRQYYAAGARL
IETNTFSANREKLSKFGLENDVRAINQAGVAIARQAVGNDAYVVGAVGSIRAARRLNVTA
EQLELAYGEQMEALLEGGVDGLLLETFYDLEEMSIALRIARRLTKLPVIGQFATDGGTIT
NDGAAYQDAFERLAAEGADVLGFNCHSGPNGILRTLEKLAPVDGVPFSVFPNAGLPSYVD
GKYAFGSKPDYFAENAIKFADLGARLLGGCCGTTPDHIAAMSKALQGYVPKSAAVAAHEP
SAEARAAAPVVIGPATEAPPAAEAVEPSLIELVKRRHTVIVEWDTPKDLDIGKFMEGAKA
LKEARVDSITMADNALAITRMSNLPMGFLVKERLGVRPLLHIACRDRNLIGTQSHLMGMH
AIGLDHTLVITGDPSRFGDLPGSSSVYDMTSFEMIRLIKQLNEGIAFSGKPLKHKANFIV
AAAFNPNVKYLDKAVQRLEKKIEAGADFIMTQPVYDAKLIENVYESTKHLNVPIFIGFMP
IVSEGNATFLHNEVPGIQLSDEVRGRMAGLSGAAGREMGVQITKELLDVAMPKFNGIYIM
TPMHFYDMSVQLTRYVWDKNGR
>A0A834ADH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllostomus discolor|TrEMBL
MDNKDSAMVNEPRGNSGPGAHWEGSSCGIENSKDSLKGSSPGLDPERRERLREKMKRKME
SGDKWFSLEFFPPRMAQGAVNLIAMFDQMGAGGPLFIDVTWRPTQDPGSDKETSSMTIAS
TAVNYCGLETMLHMTCLCQSREAVTGHLRKARRLGLKNILALRGDPPGEQWEEEEGEFSH
ATDLVKHIRSEFGDYFDICVAGYPKGHPDAVSFEDDLKHLKEKVTAGADFIITQLFFEAD
TFFLFVDACSKIGITCPILPGIFLIQSYHSLRQLMKLSKLEVPQSIRDVIEPIKDNDDAI
CNYGIDQAVSLCRKLLASGLVPGLHFYTLNRLKATTEVLKRLGMWTEEPRRPLPWALSAH
PKRREEDVRPIFWASRPKSYIYRTRDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKAPR
EELLKMWGEQLSSEKSVFDVFVRYLSGEPNQNGHPVTCLPWNDEPLAAETSLMKEELLRV
NRRGILTINSQPRVNGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLRVLKKYEL
RVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWVER
WGKLYDEKSPSRRIIQHIHDNYFLVNLVDNEFPLDSCLWQVLEDTLELLNRPMSE
>A0A6I4UW41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontixanthobacter luteolus|TrEMBL
MTDTLDPIHEAQTAADTPLFSGLPGDIEASFEFFPPKTEKMEIKLWDAVQDLAPLEPSFV
SVTYGAGGSTRERTHNTVARIIREAHLPAAAHLTCVAASKDEIREVAEQYWEAGVRHIVA
LRGDAGEPGAPFEPHPEGYRNAAELVAGLKGIADFEISVAAYPETHPDADCPQADLDNLK
RKLDAGATRAISQFFFSADTFFRFRDEAAKNGIDAPILPGILPVTNVAQARKFAGACGAE
IPQWMDGLFEGLDERPAARQLVAATVAAELCRRLYAGGVRNFHFYTLNRADLAYAICHML
GMRPKGDVR
>A0A4U2Y688|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus antibioticus|TrEMBL
MTTRKKDLRAYLKDHLLVGDGAMATQLHGVGVPVGVSFEELCLSNPRLVHEVHTSYYQAG
ARFLETNTYSANRDALSRYGLEHKVARINRLAVAIAREAAQDDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGVDGLILETFVDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYALTDAFSELKAAGADVIGLNCRLGPAELLRSFENTMIPEDALLSVFPNAGRLG
MTDGEYAFKSSPEYFGQSALRLREQGVRLIGGCCGTTPAHVKAIADALESLEPQARVNPT
IVAGDRPSITVQNTREREKPSIVERVKTATTIIVEFDPPRDLDADQFLHGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKSRHGIDPLLHIACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMDAAVARLEKKVEAGADYIMTQPVYDAESIRNVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSTEALERMKKVQGEAARQEGIAIAKELVDTAVRYFNGIYLITPFNYYE
MAAELIQYTRQQSSLVRMAQT
>A0A8J4RLM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Castanea mollissima|TrEMBL
MKVIEKIREAGEEKVVFSFEFFPPKTEDAVDNLFERMERMVAHNPAFCDITWGAGGSTAD
LTLDIANRMQNMICVESMMHLTCTNMPVEKIDHALQTIKVNGLQNVLALRGDPPKGQDKF
VQIQGGFACALDLVKHIRAQYGDYFGITVAGYPEAHPDAIGENGLATLEAYHKDLVYLKQ
KVDAGADVIITQLFYDTDIYLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKI
PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALAILMNLG
LIEETKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPRGRWGDSCNPS
YGALSDYQFMRPRARDKKLLEEWVTPLTNVDDIQEKFKKYCLGKLRSSPWSELDGLQPET
RIINEQLGKIITKGFLTVNSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSREKLDA
LVDKSKAFPSLTYMAVNKEGKLISNVHQTAVNAVTWGVFPAKEIIQPTVVDPASFMVWKD
EAFEIWSRGWASLFPEGDPSRKLLEEVQSSYYLVSLVDNDYIHGDLFAVFAEF
>A0A829RDG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 83444|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KKAKSFLIKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQVGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEITRFSCQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A3P6RDB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gongylonema pulchrum|TrEMBL
MYRFRALDMIRWIKEEYGDYFTIACSGYPTGHPEAPSYRADLLYLKSKVEAGADFIITQL
FFDSEVYEKFLRDCREIGITVPIIPGILPIQSYGSIRRITEMSQLVIPDWIRSALEPIKN
DDEAVRNFGIRHAVDLCRALFRSGSAPSVHLYTLNREASCR
>R5IBW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:124|TrEMBL
MSMLKEAFEAGKFGVTAEMAPPKGYDFSEQLEAAKLLNGKVHGVNVTDMQSASLKASSLG
LCVALKNAGIEPILQMTGRDRNRMAIMGDILSAAAFGIDTMLALTGDHPVVGDCPESKPV
YDLDSVGILKMLTKMEQTNCDCGGNEIAGGAPKFYKGASVTPVYDPIELQINKLRQKVEN
GAEYIQTQGIFDLETFKRFLDKVDAAGIKTHIMAGIIPLKAAGMARYMNENVPGIAVPQD
MIDKLAAAAAEGKEKGVKGLPMQLGIEMAAEMIAKIKDEHLCDGVHIMAIGAEKNVPAIL
EKAGVTI
>A0A4R2L3T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinisporobacter balticus|TrEMBL
MQIKNLYKNKKPVISFEIFPPKKDGPIDTIYHTIDALKDLKPDFISVTYGAGGNTVNKTV
EIASIIKNIYHIESLAHLTCVTSTKEEIENILSQLKHMNVENILALRGDFPKDPNFKFPD
PLHYQYAKDLVTHIQSKNNFSIGAACYPEGHIGCDCLDKDLFHLNTKINTGADFLISQLF
FDNEIFYSFKEKLNVQNSHIPISAGILPVINKKQIDHIVSLCGCHMPKKFIRIIEKYADK
PEALKEAGIAYAVEQIIDLLSWGVDGIHIYTMNRPKTTRKIVESISTIRNVLTEA
>A0A2W6BV73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MNLQRRIADRTGEFLLFAVTPPRLTTGPEQTKQIAEVTLERLRPVGIDGLVLYDIDDESD
RNPDERPFPFLPTMDPAVYLARDLVALDVPAIVYRAVSKYAEDGLRSWLYDQDAAQALSV
FVGASSRGKAVETSLTRAYELRAEARPDLLLGGVAIPERHSRTRNEHLRLVAKQTAGCSF
FVTQVVYDVNAAKDLVSDYRYECVAHGLEAVPIVFTFSVCGSVKTLEFLQWLGVDVPRWI
ENDLRHADDTLDASYNQAVDTAVELIAFCRRVGVPLGLNVESVSIRKVEIEASVRLAARL
RAELGR
>A0A2T7MQ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CS147|TrEMBL
MALGTASTRTDHARTVREMLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A415PPJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospira eligens|TrEMBL
MKYTGTAGILYDRLKSEILVADGAFGTYYAKKYDTGSLPELANLQASDRVLAIHKEYIEA
GAKIIRTNTFASNTVCLGAGFDEVRNNIKNAVDMAREAVKGTDVLVAADIGPIPGENMNE
KEHIEKEYVDIVNVFKECGVDIFVFETFPELGFIDKAIENAGENGFVITQFAINQFGYSS
AGFSARKLIEEAGKNSYIDACGFNCGVGPGHMKKLVQSLINRNDKYFAVLPNAGYPQVVS
GRMVFDDNNAEYFSQIMRDLAEDGADIIGGCCGTTPEYIRQMVLKTADVVHKKNASIEEE
ISEKKTANDVSFYKGKEGRKLIAVELAPPLGIDDEKIMDAAFLMKESGVDVLTFPDSPSG
RTRADSILMAEKVSRETGMCVMPHICCRDKNAIAMRSQLLGAHINDINNFLVITGDPIPS
VVRASVKSVFNFDSVGLMNIISDMNQEQFAGKPVIYGGAINQGRVNFKVELERVKKKMEA
GATFFMTQPVFSDEDIDRLRQIKEQTGARILCGIMPFVSLRNATFMKNEMTGINVTDEIL
SRYRADMSKEEGEETGIQIAREIIAKTTDFVDGYYFSFPFNRVHMLKKIIGKNNQ
>A0A8J2I340|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria atra|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSDE
YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCIGVAAYPEGHSDQSHPQHQDPQFDL
PSLIEKTKAGADFIMTQLFYDVEAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHAKLPSDMLARLDAVKSDDELVKQVGVKIMDEMLEHIKSRPDTCRRGFHFYTLNL
EKAVSHIVEDTHLIPSTLNDDDDDDEVIVETTPAINLEPPPNGFVPQRRRSSAVNSGPRN
RVIVSHSSAAKSSNHSYEATDEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGR
WGDARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKDDVSKLFRRHIEGDLEAIPWSEQS
LSPETLTISKQLLALNAKGWWTVASQPAVNGVKSTDPVFGWGPKNGYVFQKPFVEFFIPA
SEFAALKPKLDAHEQVTYFAGNAAGEFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFR
SWLDEAFSIFREWQRIYPPRSASSTLLGALRQDYWLVNVIWGDFVNGEGLWEFLEQ
>A0A851HQS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter adhaerens|TrEMBL
MESQKQFKRRFSFEFFPPKTDRGWEKLQGVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSKGISTAPHLSCIGGTRADIAELLDAYKDNGINRIVALRGDMPSGMGAGGEMRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKLGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDTASIRK
FGEEVVTRMCEKLLQAGAPGLHFYTLNQAEPSISIWNNLGISEREKIAF
>A0A6A7B7Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plenodomus tracheiphilus IPT5|TrEMBL
MHISQKLTQAREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDDALRDAYQSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKERYGNHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGATF
VVTQMFYDTDIFLEWVRKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTRCNIPKHWTEAL
EPVKNDDVEVREVGKGLVAEMCRKLIDAGILHLHFYTMNLAQATRMVLEELELLPDQRSP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPTSVRDLSDLFVRYMEGKLDSLPWSEQPITNEAGSIQYDLID
LNRRGFLTINSQPAVNGAKSSDPIFGWGPRNGYVYQKAYLEVLVSPDYISEIVGRIERDD
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAAVSPARHAIQGVVDTWYLLNIVHNDFHVTRGIFPIFDGLKVKDMDQPLQSLSGEV
ATSNGHEATNGSNGTSGTNGTEAAKGTNGTNGPNGTSGTLPEYSTKEDSSLIDAAKSAAI
EVEVTTGVKELAISN
>A0A1F6PVD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Melainabacteria bacterium GWA2_34_9|TrEMBL
MKLKEIYNSNKPIISFEIFPPKAQNIDELNQKINDLFEELRILSEFNPAFISVTYGAGGS
TRETTLDIVTKIKNNINIQPMPHFTCVGSSRGDILEYLKKIESAGIENILALRGDPPKGE
TKFVKPEDGFGYANELVEFIKLNTNLGIAVAAYPECHLECNSLDKDIENLKRKIDCGADV
VITQLFYDNSCYFEFLEKAQKQGINIPIIPGILPITSYSQIERISTLSGCKLPDELSQKL
AENKDDSEAIKQIGIEFAVKQANELLKSGVSGIHFYPLNKAFAVKTVLENIKTEQKV
>A0A839FBT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium sp. P30BS-XVII|TrEMBL
MSFFRQSRRADLGTNIKVSFEFFPPKTEVMEERLWETVTRLAPLNPEFVSVTYGAGGSTR
ERTARTIKRILTETDVNAAAHLTCVDATKEEVDTVVREFAAMGVKRFVALRGDPAGGVGA
HYKPTPGGYENGADLVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVEKVRRAGIYIPILPGILPIHNFTQVTNFCSKAGTHIPSWLAERFE
GLDNDPQTHALVSSAVAAEQVLDLVERGVQDFHFYTMNRADLAFAICHLIGIRPASGTLE
PALAGAA
>A0A4Q2EK51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevilactibacter flavus|TrEMBL
MPAQTIAERLAVADRPTFSFEYFPPADDAATQQLIGTVDALSPLRPDWVSVTYGATGAVR
YKTFSAVGAIRGQTAARTMGHLTVAGQSRDEVRRAIESYARLGVTQILALRGDPPGGGAF
ERHPGGLGNATELVRLIASMGEFSIGVAAFPDGHPDGDLDLDARILLDKQEAGAEFAVTQ
LFFDADAYFSLVERFRALGGTMPIVAGIMPVTVPSQIERFASLSGSRMPAAFETELRAVA
DDKQRFRQVGIDLVTGLCDQVLRGGAPGLQFFTLNRSTATAEILGRLRAMP
>A0A4Z0LZQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haliea sp. SAOS-164|TrEMBL
MAKQQPRISFEFFPPKTAEGKKKLLEETVPALNALDPGFFSVTYGAGGTTRDSTLGVVSS
IREAGIDVAPHLSFGGDDEEAVGALLDTYRERGIRHLVALRGDMPSGMGAATQLVYANQL
VEFVRERTGDHFEIAVAAYPEIHPESRSYDSDVHYLKQKLDAGANFAITQYFYNVEAYFY
YLDQCAAAGIDKPIYAGIMPITNFTNLARFSRNCGAEIPRWICQRMEGYGDDQESVRKFG
LEVVTQLCQTLVDSGAPGIHFYTMNQVEPTRTIHSNLGL
>W1DRD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae IS43|TrEMBL
MSKMFEGLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRP
A
>A0A0M9EKB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shimia sp. SK013|TrEMBL
MTTPQVSFEFFPPQSLEASFRLWDTVQALAPLDPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNASKAETLQIARDFADAGVNEIVALRGDPPKGSDGFQPHPEGFANSV
ELIEALSGTGDFTIRVGAYPEKHPEATDMQADIDWLKRKLDAGADEALTQFFFEAEGFLR
FRDACAKAGITAPIVPGILPIENWKGVRNFARRCGTTVPTWLEDAFEKATRDDREDLLAT
AVCTELCSDLLDEGVDALHFYTLNRPELTRDVCHALGVTPQVRLENVA
>A0A7S9LJ30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fulva|TrEMBL
MSVLKTALQEQQFACVMEFVPKPSAERFAAMDAIMARGQVCGWPMTLAIGDRVSSPLDMS
PLDALACFEHPVPALPHFSGKDRERHHLLAQMRRMDAAGQHQLLMLTGDRLPGHTPGERP
VRYLESVAALQIARQAYPHWWLGAALNPFKYREEEGAAQYLKAEKKLAGGADFFILQLGF
DAAKHQEAMHWMRRQRAPKPLLACLMSLTQGRAGMLDHVAGVTVTPSMRQMLEAETAQSK
AFAQARSIDRLALQVIGVKLMGYAGVHLSGIHEPSQLLALEARLEHWQAHVTTLEQWAPA
WQASWQMPGLPAVTFHPPQAAWREGESRVVATFAQKARYHAMHGMHGLLFSRSNPVSQLF
GWAVRQPMWTTGLGAQVLHSLERAVKRPLLGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTTLNRCEFGDRECIHSAKYRTAKAVRQTDVLAQRLIPCVEQHTRHRSSWPGWFGAQAQ
PVTRPSAPRSRPES
>A0A7H8YS24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 902|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVESCKNNNEVKQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A8C0IWQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chelonoidis abingdonii|TrEMBL
MVNEPHSASSGSASSRSDGSSSGSEGSKDSSRCSTPVLDAERHERLREKMRRRYDSGDKW
FSLEFFPPRTANGAVNLISRFDRMGMGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETVLHMTCCNQTKEEITGHLQKAKHLGLKNIMALRGDPIGEEWEEEVEGFNYAVDLV
KHIRCEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVSAGADFIITQLFFRSETFLTF
MKDCQAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKEVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVSGLHFYTLNREVATTEILKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIHRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELMSEESLFEVFTCYISGKPNRKGHKVTCLPWNDDPLAAETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEITTALLKVLKTKKYELRVN
YHIVNVWGENITNAPDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENFTAARSVHPPAHCRQHNCHGARGARLA
GQGARHSAQGSQPLCSRLLIEPHSLSCSARGTRLSLPERDSIRASQRPICYKLTL
>A0A7K2KCQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4937|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRIESVRPSFVSV
TYGAGGSTRSGTVRATQQIAADSTLTPVAHLTAVSHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A7C9RJI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Afipia apatlaquensis|TrEMBL
MTSEATAPAGSQGQKRPAISFEFFPPKTEEMERNLWEVINRLAPLTPDFVSVTYGAGGST
RERTHSTIARILTETKLTPAAHLTCVDATKADIDDVVARYHDVGVRHIVALRGDPVSGIG
NAYTAHPEGYQSSADLVASIKRHHPDMEVSVSAYPEKHPESATLDADIDALKAKVDAGAT
RAITQFFFDNDLYFRYLDRVRAAGITIPIVPGILPVQNFKMASNFAKRAGASMPEWLSAK
FEGLDDDADTRRLVAATVAAGQVQKLAKHGVENFHFYTMNRADLVFAISHLLGIRPNGAQ
KAA
>A0A1V5N4Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium ADurb.Bin412|TrEMBL
MADKKRLKGLVRRSERFLVLAEFVPLPGHNIANFEKFLQEYASAKDRIPGEFELAGITIP
QSPGGVASMSPADIYSILDKKGLWADLDVVPHVTTKDHNKDGIISYLTGLQKLGIESVLA
LTGDKPADSKGVFELDSTDLIALLKEMNCDSLAKAKPGSFDKAHQFYIAAAVSQYKYTEA
SQMQQYFKMGKKLMAGADCLITQLGWDWRKCEELFRYLKEQSLDTPVFGNVYVLTTMTPA
PRLMHTGKLPGCVVTKELFEKLGSETPEQHMDRAAQQVAMFREMGAVGIDLGGLLDFGMM
IEILEKAQKIGKNWREYQNNLDFGVKGGFYLYKGENQRRTLSKPSPGFHKRSFDMFHNVF
LAPGKGLHGGLKKLFGASKGLREGRGLLYKMFFDGFEKPVKSMMFDCEECGDCFLVENFG
ICSMGKCEKGLTNAPCGDANPDGTCGNNPDITCVGELIYKAAASEGEQGLKRLAETLNRK
RDAQLAGTSSILNYLFEKDHMKKVKLIQIGESVHASIPKPGAAMRELLGKGADAYEKPSG
ALDYMVSLITSQVAYHADYIAINVDAFGEDDPKLAAELMRQYVHLVKKHGKGVPPCVDSS
DDNVLQAGLEEYYRELPKNSPKPLINSVKTYTIDRILPLGKKYPFKVIGLLVSDKEAGSD
GAYSTDQLYRMAQEIFEAAVGKYGFTPDDLFFDSTVFPLAIDMPMSPDTPGYTYRAFETI
RKIMTDPKMKGVHTSLGISNSVKDLPGRKIGVCRAYVAKAMEYGLDAGIVNVTHEYGLKP
VDAELLELVDAFARQDGSAERSMKAMELMGGFCRANRKTSR
>A0A5R9LWF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. So13.3|TrEMBL
MALGTASTRTDHAVTIRELLASGERSYSFEFAAPKTEKGERTLWNAIRRIEAVGPTFVSV
TYGAGGSSREGTVRATDRIVSDTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNILAVR
GDPPGDPLGEWVKHPQGLLYAADLVRLIKESGDFCVGVAAFTEMHPRSSDWESDTRNFVD
KCRAGADFAITQMFFDADDYFRLRDRVAAAGCTTPIIPEVMPVTNVRQIERFAQLGNAPF
PPELADRILAVKDDPAAVRAIGIEFTTEMCRRLMAEDIPGLHFITLNHSTASLEIYENLG
LHQRS
>A0A2M9L6Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora sp. CB02891|TrEMBL
MALGIPSTRSDRAQTVRDLLAAGDRSFSFEFMPPRSEEGERKLWDAIRRVEALDPNFVCM
TYGAGGSSRGRTVNLVGRIATETTLTPVAHLTAVDHSVAELRNIIGQYADEGVRNVLAVR
GDPPGDPMGEWVRHPDGVSYAYELVELIKGIGDFCVGVAAFPQMHPRSTEWDEDIKHFVA
KCRAGADYAITQMFFEVEDYLRLRDRVAAAGCETPIIPEIMPVTNIRQLVRFPQLSGSDF
PPEFRRRLEAAAENPAEVRAVGLEHATAMAERLLAEGAPGLHFITLNHSTSTLEIYQNLG
LNKR
>A0A5F2GZI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.220.01.1.1|TrEMBL
MTIRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A1C3V7M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium yuanmingense|TrEMBL
MTDLTTPATADRQDRHLKRPAISFEFFPPKTEEMERNLWETINRLAPLEPKFVSVTYGAG
GSTRERTHSTITRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPVG
GIGTPYSSHPEGYQSSAALVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDA
GATRAITQVFFDNDLYFRYLDRVRAHGIDIPVVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>C7N1R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Slackia heliotrinireducens (strain ATCC 29202 / DSM 20476 / NCTC 11029 / RHS 1)|TrEMBL
MHIAKVYEPGKIPVSFETFPPKGEMPVEEARGLMAGLAPLNPAFVSVTYSAGGAGNSERT
VDVAKMGQDEFGLTCMAHLTCMGATKESVAREFERMREAGIENVLALRGDKVPGRDADVF
HYAKDLIPLAREAGFCVGAAAYPEGHVDCLDFDASIRHLKEKQDAGAEFFVTQLFFENDV
ALRFLDAARSAGITVPITFGIMPFMSKAQLTRMIFMCGASLPSPIIKLLNHYEDDEESLR
QAGIEYACNQFVELGREGVDGLHVYTMNRADIASAVMEALRGAGIV
>A0A2R6NF96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hermanssonia centrifuga|TrEMBL
MKISKKIEQAEKENRTWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
DLTSELVKTCQGLIGIETCMHLTCTNMPAEKVDAALKDAKANGCRNVLALRGDPPLGKDE
WEAVEGGFVHGVDLVKHIRKNHGDYFDIAVAGFPQQQLLPAEELAQEIQWLKEKIDAGAN
FIFTQMFYDVDLFIAWVNTVRAAGIKVPIVPGIAPIQTWNGFMKSTTLSRTTIPQSLLDQ
LEPHKNNDEKVRELGTKLVADMCRRILDEDIGIRGLHFYTMNLEKGTRMLLEELKLVPRI
EVVKPLPWRQSLTPNRRTENIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQSKEEAYKLWGHPTSTFDITTLFARFCLGQVPALPWSDTAPASETSVISSQLA
KLNELGFLTINSQPAVDGVRSDDKVHGWGPSNGYVYQKAYLEFFVSPELLAALLPYIERD
PNITYYVINKRGDLRTNNHSDGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGRQ
WAKYYEPDSPSRKFIDELMENQLLMNVVHNDFKRPDAIFEPFFKAGSELAAAQQTPAAAT
NGAPNGNANGHAR
>A0A1W9TS44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_19|TrEMBL
MNLKEALKKKRFVVTSEVQAPLGDDTPEEMVEHLNKVRGRVDGVAISEVELEGVVGDSIK
TCEILNENKFNAIYQTTTRDKNRYQLQKDLTLAHETGVENLLVFTEDYRISGDSLQESMF
FHVDSGKIASVLDHMKEGQTIDGKELPSKMEFVLGSGVETPLGKNVPKRGMEEMEDMMNV
GTGYFLTTPIFDVDQFAKFMKQVDTFNVPVIAEVMILRTAGMGKFLNRHFKPGLVPDWAI
KKLLQAPDQSKASIELFADTIKSLKDLCQGVHIITIGGEDKLANYLNAAKLK
>A0A0Q4XVI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. Leaf99|TrEMBL
MPTASQHRASRDGYRPIRVSIEFFPPKTDEMEQILWKSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETGLKPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPQDGVG
TTYRPHPGGYAQTADLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFENDIYLRYVDKVRAAGIDIPIIPGILPVQNFKQSANFARRTGASVPYWLAARF
EGLENDPDTRRLVAAAVAAEQVLDLVDQGVNDFHFYSMNRSDLVYAICHLLGLRAPAPKV
EAAKAAA
>A0A657B1P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleiphilus sp. HI0066|TrEMBL
METQKQFKRRFSFEFFPPKTEEGKAKLQVVRDELARRKPDFFSVTYGAGGSTQERTIDAV
LNFQDQGISTAPHLSCVGSSTQEIASLLDLYKERGVNRIVALRGDLPSGMGGSAGELKYA
NELVEFIREHSGNHFNIEVAAYPEFHPQAPSAEEDLINFKRKVDAGANSAITQYFYNVDS
YFYFIDRVEAMGVNIPVVPGIMPITNYTNLVRFSDMCGAEIPRWIRKQLE
>A0A2V9AVS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIHDFNERLKDAILIADGAMGSMLHEAVGPQRCFDELNATEPEAVFRIHQAYIEAGAQI
IETNTFGANRFKLAPLGLGDKVQRLNSRGVKIAREARESAAREVLIAGSLGPLGLGVQAR
HPDDKEILDVFYEQALALEERGVDFYILETFSYIEEILLAVDAIRSFSGLPIVAELTYSE
EGTTHGDIRPSDAASRLKNKNVQVIGANCTLGPQALLPILQELSAVDDIRISAMPNAGFP
KREGDRIVYPKSSPEYFALFAREAAALGVRILGGCCGTTPAHIRAMAEAVKSLRPAQTHA
VGPTVEAVAKPTPIPISQREPESNFWKKLNKKEFAVCVEIDPPKGLSLDRIFEQVDKVMA
SGKVDVIDINSGAMARVGMDALVVAGALEGRGVETIPHLTTRDQNIIGLQAGLLGAWTVG
GVRNVLAITGDPPSVGDYPETSGVYEVDSVGLVKVLGRLNQGTDWAGKTLGGATNFAIGV
ALNPVADDVDNEIARFHAKVEAGAHFAMTQPLFDPEHWRAFLKKLGGGQPRIPILIGVWP
LNSYKQALRLNNEVPGIVIPESLLRSMERAGASARDCGFQVARQMLAWARTELAGAYLIP
PFKRYEEILEIL
>A0A2V3JDF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanophagales archaeon|TrEMBL
MAEEVYSDLMREIKSGRFVWTGELEPAKDIGEAIEAARELKGLVTACNVTDNPQSFAAIN
SLAAAYKIQQETGMECIYQLRCADRNRLALCSDVMAAGILGLKNILALTGDYVSLGDTPR
AKPVYDLDSTTLTRMIHTLVHEGKDISGTEIPNPPKLHVGAAAGPGVDPLEPELYKMKRK
ALAGAEFFQTQVVYLPEVLDRFFKGVKELNIETPILVGIFPAKSYGAAKFFDEYVTGVDV
PPDFLKELEATKQIKDKEKRKEEVDRVNIEYFTGFLEHLKDTPAVGCHIMAVGYPRIIPE
LKKVME
>A0A2V7Y2K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MQDFIQAIADEHVYLFDGAMGTMLYSKGVFINKCYDELNLRSPEIVLEVHKQYVRSGAEV
LETNTYGANRVKLRTFGIEDDTREINVKAVEIARKAAGDSVYVAGAIGPLGIRIEPYGPT
ALDEAREYFREQAEALRDAGVDLFILETMSNIAEVEQGILAIRDVCSLPIIAQMTIGNDS
RTIYGDSPRLIAERLDRAGADVIGLNCSVGPDVMLDAIEEMSTVTAKKLSCQPNAGLPRE
VAGRQMYMASPEYMGKYAKRLIHKGVKFLGGCCGTTPEHIKVMADAVRPLSPRRSFVIIE
RDIEAKKPQGFQPVPLETRSNWGRKIAAGEFVTTIEIVPPKGPNPEAMVKSVQSIKGAGV
DAVNVPDGPRAQNRMGAIAVAVLLQQRVGIETVLHYCCRDRNLLGMHSDLLGCAALGLRN
MLLITGDPPKMGSYPDATAVFDIDAIGLTNMVSLMNRGLDLGGNPFGEATKFTIGVGVNP
GHLDLDYELRRLDWKVKAGAEYAITQPVFDVDVLEKFLKRIELMRLPIVAGIWPLLSYRN
AQFMNNEVPGVSVSDEVMERMRIASEKSKEHALHEGVTIARETLERVRGQVAGVQVSAPL
GRVDLALQVFSQGPLPGERVARSAG
>R6YU60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:309|TrEMBL
MIDSLVEKLKKKVVLADGAMGTYFSQKYMTEMEAEEANIATPERIIAIHKEYIEAGAELI
RTNTFAVNHGLFEEAEKRKEVIEAAVANAREAVRQSRKEVVVAASVGPIRQSAEEEDGKI
WKEYTQMLDVFYDLGIRVFLFETFSELRWLPKLAEYCKNREEQTIVIAELALNPMGYTQH
GFGITEILQELTADDNLDIVGFNCGVGALHMKKLLERQYFPKECLLSVFPNAGYQQEMQG
RTQVFHDTAYYAGQMKAILALGANLVGGCCGTTPGHIRALKKVVQKQEQVQPKKVAEESE
NVDEIKDNPTPFVRKLREGKKVFVVELDAPFDASSDKFRKGVCALQENGVDIITVSDSPM
ARSRADASLLAVYAKKCADVEIMPHVAMRDRNLIGLRSEILGAHVNGIRDFLVITGDPVG
SNDRGKITGVFDVNSIRFMEYLKHMNEEVFQEEPVYYGGALNYAGINPAAIAGRMKKKME
AGCRYFLTQPVFTEEDIERIRELKKMTGAKILCGIMPLVSYRNAMFMKNEMPGIHVSDEI
VSQYQPDMTKKDAEETAVKISLEVAEKLLEVADGFYLMTPFHRVALVNRIIDGIRRLLG
>A0A7K5UK25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cephalopterus ornatus|TrEMBL
MVNETQQSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEIDGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFFK
FLKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
EEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGHKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7G2S5M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp|TrEMBL
MSKRISFEFFPPKTDAGKEKLLATQQKLLAKNPEFFSCTFGAGGSTRDNTRDMVNQLRNQ
HGDTAPHLSCIGQSREEILELVNGYKAAGVTRIVALRGDLPSGMGYAQSEIKYADELVQL
IREETGDHFTLEVAGYPEMHPQARSFEDDIAHFKRKIDAGANSGLTQYFYNADAYGYYLD
ALQKIGCDAPVYPGIMPILNVANLVRFSSTCGADIPRWLHSKLNDIKDDDAAVKAFGEEV
VTRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGL
>A0A7V9CIP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MDQSCLDALRDRVLICDGAMGTQLYARGVFLNRAFEDLNLSQADLVVAVHQDYLRAGADI
VETNTFGANRLKLASFGLADKVAAINVAGARIARHAARDSAWVAGSIGPLGIRVEPWGKT
GLDEAEEVFAEQAGGLADGGVDLYILETFRDVNELGAAIRAIRGVSARPVVAMLTTGEDG
NTLDGTPVEQFGPQLVGFGADVLGVNCSVGPAAMLDTVERLAQAVPGALLAAMPNAGKPR
DVDGRNLYLCSPDYMASYARRFAAAGVRLIGGCCGTTPDHIRQIRTAVHALSAPAPAAAR
STGLVPATRDPVTPVPVESRSRLANALRRRQFVTGIALVPPPGFGHDAVVEQARQARIRG
LDVVLVGDGSGSRARMSALATAVTVEQSVGVETILQYCCRDHSLHAMQADLLGAHALGLR
NLLLVTGRPLRRSEYPDATAVFDVDSIGLTNVAARFNRGEDVGGQPIGSPTAFHIGVAAN
PTAVMPDRELSRYTYKVEAGAEFVVVGPIYDVAALEQFLDVTRAQRVPVLATVKAFDSAR
QAEQLANEEPGVSVPDALVRRMLDADRDGRVAAESLAIARELVVAIQPLVAGLIVAAAGG
RVDAALDVLAALGADRPAAIDADRAQPA
>A0A840RXT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciimonas immobilis|TrEMBL
MSSANFSIEFFPPKTPDGAEKLRVTRAKLAELHPKYFSVTFGAGGSTQKGTLDTVLEIRG
EGHEAAPHLSCLGSSPESLRAILAQYKANGIKRLVALRGDAPSGYGGVGLMSGEFRYANE
LVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDVKRFADKVKAGANGAITQYFYNADAYF
EFVEQAHKLGATVPVVAGIMPITNYSQLMRFSDMCGTEIPRWVRLKLAAYGDDADSIRAF
GLDVVTHLCERLLAGGAPGIHFYTLNNAAATTAILQRLK
>A0A7Y2XFM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MSSENAGIMAGLLEQAYMEIIPTKTIAERLVHVPRHSYVSITCSPTRGIEPTLDLTERLR
ALPEERRLKLVPHVAARVVRDKGHLREILARLDELEVESVFVPGGDAPTPAGDYDNSLDL
LRDMADIGHRVGDVGIASHPEGHPLVDDAELLRLLAEKQPLATYLVTQMCFDPDVLIRWL
RRIRGAGIRLPAWIGLPGVAEIPKLIALSMRIGVGQSVSVLKKQKGLVRKMLSAKPYAPD
ELLAGLQPQLDDPALDIPGFHLFSFNNVEATERWRSETLRHLNGGLQ
>A0A7W9Q171|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces echinatus|TrEMBL
MALGTPSTRTDRARTVRDMLATGKATYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLAYAAELVRLIKESGDFCVGVAAFPEMHPRSEDWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCATPVIPEVLPVTSVKMLERLPKLSNAHF
PDALKERILTAKDDPATVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A2V8NWC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRDFLSELRNRVLICDGAMGTMLYSKGIFISRCFDELNLSKPELVREVHLDYVKAGVDII
ETNTFGSNRTKLMSHGLEAQMREINVQGARIAREAAGDDIFVAGAIGPLGIRIEPWGKTS
IDDARAIFRQQAEALLEGGAGIFILETFSDLNEVFAAIRGVRDVSDRPLVAQMSIEEDGN
SLEGTPPEVFTRRLEEWGADVLGLNCSVGPHTMLESIERIASVTAKKLSVQPNAGKPKNI
EGRNIYLCSPEYMASYAKKFVEYGVSIVGGCCGTTPQHIKAIRSAVRSVSPPFQPSPAAS
RLSSASGAMAAYLERGRGESSDAIPLEQRSRLGYKIARGEFVRMVEMIPPMGHDFSQAIE
RAKYLQAHNVDAINVTDAPRSSARMSAISLAILLKESTEIESLAHYTCRDRNLLGMQADL
LGAYALGLRNLLLITGDPRLTGDYIDATTVFDVDSIGLTNMVHRLNRGIDVGGKSIGKPT
GFVIGVGANPGAIKDDDELKRFHYKVEAGAQFVLTQPVFDQGVLEQFLRRIEDCKIPVIA
GILPLANHRAAEFLNYEVPGCSVPDSILERMRRADNPEPARAEGIRIAQDILERIQGMVQ
GVQVRGPFDEYETPVEVLSVLNLKGASR
>A0A2V9V3Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MAGNFLERLAKSPVLCDGAMGTLLYSKGIFINRCYDELNLSQPELIRGIHHEYLQAGAEI
IETNTFGANSFRLARHSLTDRVRDFNLTGAKVDVWVAGSVGPLGVRIEPLGKTSFEEARA
AFREQIAALVEGGVDLLMLETFGYVEELHQAVLASRDVSPNIPVVAHVTIDEDGNCLDGS
DPEAFTARLTEWKVDVLGINCSVGPVAMLEAIERVRAATDLPLATQPNAGMPRSVEGRNI
YLCSPEYMASYTRKFVAAGVSLIGGCCGTTPEHIRAMKSGLRVREARQKIAVSSISHEHA
TAPPPAAVPLAERSRVGGKIARGEFLTMVEIVPPKGIAIQKEIEGAKFVKSVGVDAINIP
DSPRASARMSNQALALLMQQEVGIEAILHYTCRDRNVLGIQSDLLGAAATGIRNLICITG
DPPKMGNYPDATAVFDVDAIGLVNIVRNLNCGLDLGGNTIGQGTGFVIGVGANPGLPSLD
EEIRRFEYKVEAGAEYVVTQPVFDLNLLENFLKRIEHFRIPVIAGIWPLVSARNAEFMKN
ELRVSVPDNIMQRMTGASTPEAAREEGVAIAREMLRAVRHRVQGAQISAPQGRYTSAVDV
LEALGYVSDATAESFFQEICTRNF
>A0A368TG37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanophagales archaeon|TrEMBL
MGDEVYSDLMRELKEGKYVFTGELEPEKAGDVNEPIEMAKELVGMVVACNVTDNPQSFAY
VNSMAASYLIQKEAGMECVYQLRCSDRNRMALLSDVLGAGALGLKNILALAGDHVSLGDT
KDAKPVFDLDSTTLIKLIRTMVDEGKDLGGNEIHNPPKLHVGGAAAPGAAHLKAEVGKVK
RKINAGVEYLQTQVVYYTDVLDKFFNELGKVDVPILVGIFPARTFGQADFFDKYVAGVDV
PPDYLEAMRATKAIKDKEKKKEEVDRVNIEFFTGFLEHLKGTPAAGCHMMAVGYPRIIPP
LKKLME
>A0A839K464|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variimorphobacter saccharofermentans|TrEMBL
MHIASLFQKKRTVLSFEVFPPKKTSSIDTIYSTLDDLQGLKPDFISVTYGAGGNAGDSAT
AEIASAIKHKYHIEPVAHLTCVNYTKPEIEQILERLEQNNIENILALRGDISPDRMPKKE
FNYASELIAYIKERGGFHLSGACYPEGHIESENLISDILNLKKKVDAGAEHLISQLLFDN
NYFYSFLEKARIAGISVPIQAGIMPVVNKAQIERMVTLCGASLPPKFTKMLQRFEHSPEA
LRDAGIAYAVDQIVDLISQGVDGIHLYTMNNAYIAKKIMNSISGLIED
>A0A2V9MZU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPREFLARLKTSPMLCDGAMGTLLYSKGIFINRCYDELNISQPDLIRAIHHEYLQAGAEI
IETNTFGGNAVRLERHGLQDKVHDVNFQGARLAKEAAKSFDSWVAGAVGPLGIRIEPLGK
TSFQEARDIFREQIAALIEGGVDLLMLETFGYIDELHQAIHAARELDPRFPIVAQVTLDE
DSNCLDGSTPEIFAPRIEEWGADVIGCNCSVGPVSMLDSIERIRAATTLPLSAQPNAGIP
RSVEGRNIYLCSPEYMASYARKFVTAGVRLVGGCCGSTPEHIRVMKSALRVTQARARTGE
TAAKTQTAAPVVASIPMEQRSRLGAKIAHGEFLTMVEIVPPKGTNIQKELEGAKFLKSVG
VDAINIPDSPRASARMSNQALSLLLQQQAGIEAILHYTCRDRNVLCIQSDLLGAAAIGIR
NLICITGDPPKMGGYPDATAVFDVDAIGLVNIVHNLNRGLDIGGNPVGAGTGFVIGVGAN
PGVPNIDEEIGRFEYKVEAGAEYAVTQPVFDLSLLEKFLRRIQHFKIPVVAGIWPLVSAR
NAEFMKNELRVSVPESIMERMTRATSPEAAKEEGIAIAREMLIAVRHMVQGAQISAPQGK
YSAAVDVLEALGSSGAKAG
>A0A7W1VCM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRNFRELLGGDGIYVFDGAVGTRFYDKGVYINRSYDELNLTAPDLVREVHTEYVKAGADI
IETNTFGATHHRLLQYSLENKLREINVAGARLARHAAGENVFVAGAVGPLDLRIEPYGPT
SFDEAREMFKEQIAALLEGSVDLFVLETFSDLSEIQQAIKAVRELCDLPIVAQMTIATDG
KTIFGADTEILAGRLDEYGADVIGLNCGVGPTHILTALEKMRAVTTKKLTAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRFIKAGASFIGGCCGTTPQHIKLISDAVRAVSPRQSKAVKP
TTETVKVIDLKPVDVEIIPPEMRSKWSRKIALGEFVTSVEVLPPKGCDAAKTLESIKLLK
TAGVDAVNIPDGPRAQTRMSAQATAILVEREIGIEAVLHYCCRDRNLLGMMSDLLGAAAL
GVHNLLIITGDPPKMGPFPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGRPTAFSIGV
GVNPGAINLEEEIRRFEWKVEAGAEYAITQPVYDTKQLRDFLKRIEQVRIPIVAGVFPLV
SIRNAEFMHNEVPGVVVTQEILKRMRVASDKSKEDARDEGIKIARESLTEVRDLIQGVQV
SAPFGNVKYALQVFDVLDELKSIGEAATIS
>A0A2V8IKQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MQDLLTRLENHVLVCDGAMGTMLYSKGVFISRCFDELNISNPELVREVHLDYIKAGADII
ETNTFGANRTKLMTHGLADQIRHINIQGARIACDIAGDNILVAGAIGPLGIRIEPWGKTA
IEEAQVTFREQAKALVDGGVHALILETFFDLNEVYAAIRGVRDVTDQPLIVQMSIEEDGN
SLEGTPPEVFAKRLEEWGADVLGLNCSVGPQIMLDAIERIANVTSKKLSVQPNAGKPRNV
EGRNIYLGSPEYMASYAKKFVQYGVRIVGGCCGTTPQHIKAIRAAVKSVGVAVLGHSPGA
SRRPLSAGEGTEGESSIPLESRSRLGRKLATKEFIKIVEMIPPIGHDFAKAIEKAKYLQA
QDVDAINVPDAPPSSARMSAISLAVLLEKSTEIESLAHYTCRDKNLLGMQSDLLGAYALG
LRNLLLITGDPHQIGEHSDATAIYEVDSIGLTNMVSRLNGGVDVGGKSIGKPTGFVIGVG
ANPGAMSDLELKRFFYKVEAGAEFVLTQPVFDATVLERFLDRAGNSKIPVIAAIVPLPNY
KTAEFLNYEIPGCSIPDSILERMREAQSKSPEHARNEGILIAQEILERIHAMVQGVQIRG
PFDRYETPVEVLSVMMKGATV
>A0A7W1L2C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
SNWAHRLVNGEFVTTVEVLPPKGCDAAKTLDQIRLLKTAGVNAVNIPDGPRAQTRMSAQA
TALLVEREIGLEAVLHYCCRDRNLLGMMSDLLGAAALGLRNLLLITGDPPKMGPYPDATA
VFDIDSIGLTNMVNKLNHGLDLGNNPIGCPTSFCIGVGVNPGAINLEEEIKRFEYKVEAG
AEYAITQPVFDVAQLRDFLKLIEHVRIPVIAGIWPLVSYRNAEFLHNEVPGVRVTSAIME
RMRRASDIGKEAARDEGLQIARESLLEVRDLIQGVQVSAPFNNVRYALEVFEALPEFNSS
RTADATRATG
>A0A8I0M7F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. ENS10|TrEMBL
MSPDINPFDPGAPLEPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGVG
PMASAKTARWIRSNVPGIHIPDSVITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGIHV
MAYRQEEYVAEIVHESGVLKGRRPWKHETLPEDALVAERLEHIREGKEENQQEMAEAAAH
HPH
>A0A662E220|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKVTEHLDRATRPVISFEIIPPVRGGNLRDLTSLIEDLVKYEPPFIDITSHAAEAIYEET
SDGIKKKIKRKRPGTLGICALIQNKYNVDAVPHILCHGFTREETEDVLIEFRYLGIDNVL
AVRGDALDYKKTIEGHRTVNRWAGDLVQQIADMNRGIYLEDDLLDADASEFCVGVSGYPE
KHLEAPNLKTDLDRTKAKIDAGAEYVVTQMFFDNRHFFEYEKRCREIGIDVPIIPGLKIL
TSKSQLTTIPGTFHIDIPADLSDEVMAAKNESVAEIGLEWTMRQAEELLSRGVPALHFFV
MQNSRAITKLLDRLQP
>A0A2H0DP27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG22_combo_CG10-13_8_21_14_all_63_91|TrEMBL
MRIPSLYGRGTPVFSFEFFLPKAPSDMDRFRKTVVALKALAPDFVSLTYGAGGSARTQTI
ETAEMIKREIGIETACHLTCVAHTKAEIDEILDRIERSGIENIVALRGDMPQDREPIPAA
RRELPFAADLVRRIRVRGGFAMGVAGYPETHPEAVSPEADLARLKEKVDAGGEWVITQLF
FDNAVYFDFVDRARKIGIQCPIVPGIMPVASIKQTKRFTEMCGTSLPKELRDGLDAVADD
PEGITRFGIDYATRQCRGLLAGGAPGVHFYTLNKSRATATILAKLRDS
>A0A2E8FZL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp|TrEMBL
MKRISFEFFPPKTEQGKEKLLATQNKLLVKKPAFFSCTFGAGGSTRDNTRDMVKKLREQH
DDTAPHLSCIGQSKEEILELVNGYKDAGVTRIVALRGDLPSGMGYAQSEIKYADELVQLI
RQETGDHFTLEVAAYPEMHPQARSFEDDIAHFKRKVDAGANSGLSQYFYNADAYGYYMDA
LHKAGCDAPVYPGIMPILNVANLLRFSNTCGADVPRWLQSKLNDIKDDDGAVKAFGEEVV
TRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGM
>A0A2W0BHI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
EEIDAILLRYAKSVIGNILALGGDRPAGMAYDKSRDSFQHAIDLVKFVRLFNESGVHRDR
RGFGIGVAGFPEGHPATPNRLVEMDHFKAKVDAGADYIVTQLFFDNRDFFDFRERCGLAG
VHIPIIAGIMPITSITGLKRMAELAGGARFPAKLLRALQPCQNDPDMVRHVGIQYALEQC
HDLLTNDVAGIHFYTLNQSGATRMIFDSLGIPRNRNLQASNV
>A0A399XXC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTEKSNLQLVLESGAFAVTAELGPPKGADAEPVRRKSRILKGYCDAANITDNQAAVVRMA
SWAGALIAIEEGVEPIMQMTTRDRNVMALQSDLIGASALGIRNILALSGDPIKIGNHPDA
QAVSEIDSTALTAMISAMKGEGIFANGEKIPTPPSFFVASAANPTMDTAEKIESKISAGT
DFFQSNIIYDIAAFRAWFEPLRDSGAFGTAPFLAGVTPPKSEQILRHMHDKIPGVTVPDE
TFQRMAGKEGKAAEEAGMAIAVDVIEAVRQIDGVAGVHLMAVAWEEAIPEIVETAGLR
>A0A1G6R247|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurella multipotens|TrEMBL
MSIASLIAKKKLLTIEFNPPKNTDIQKHILKLEPFKNIVDAINVTDSPMAKPRMNSIVSA
NFIKDISEPIFNLTCRDKNKIAIQSDLLAASALGLKNILAITGDPAKDNDSVYKINVFEL
IKLIKNLNEQFNTGFFIGCASDIPKTNNISSIESRLKRKSEIGAEFVITQPIFSKNDLER
FLEASNNIKIHKIIGIMPIVSYQSALYLNNNVKGINIPKFILSKFENASIEDFKLITFEL
HNKLLNDIKNLLPYIDGLHIMKLDYEIAQLTKKFLEV
>A0A257CZF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. PGPPP3|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GDIKVPTAPHLSCVGDSVEELRSLLKLYQDAGIKRIVALRGDLPSGMGIASGELRYANDL
VEFIRRETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKARAGADSAITQYFFNADSYFY
FVERVRSLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIDSIQAFG
EQVITQMCEQLLAGGAPGLHFYTLNQAEPSLAIWHNLKLPR
>A0A1Y0N0W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. SA4-12|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPKKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYLD
KGNGLLDKRITRMRPGTVGICASIMHKYKVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKDEPYFKPVKGGNAFATELVDQISNLNRGKYLHDDVNVEHHSDFCIGVAGY
PEKHMEAPSLVSDLRRLKEKVDAGADYVVTQMFFDNNKYFEFVKAAKEIGINVPIIPGIK
PIAVKRHLQILPQVFKIDLPQDLIDAVDGCKDNKAVRQVGIEFAIQQSKELKAAGVPVLH
YYSMGKSDNVQAIASELF
>A0A1F4EJW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_65_14|TrEMBL
MSFPASATDLGLHARLTELLIGGSLEISPRELHRAPHVAALLPANTCVYIPSLPGLPLAR
TLQAVAAIRDAGLDPVPHVSARRIRERDEFRDFLKRATAEHGVHRVLLIGGDEPRPLGPY
NDSVQVLEEGVLSECGVREFGVGGYPEGHPRISLAALEAALRRKVDIAAEQGLGIYMVTQ
FSFAPARVVDFCAGLARSMPDLPIYVGIAGPTDPVALARYAQRCGVSVSLRALRNLGTGI
AKLVTHTDPREHVMAIARYARNREPSNVVGVHLYSFGGAERTAAWMRELIA
>A0A177L3G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Domibacillus aminovorans|TrEMBL
MTLLDRLKTDVLTADGAMGTLLYSHGIDFCYEELNTEKPEIIEKIHKDYIAAGADVIQTN
TYGANAIKLARYGIENRSRELNTAAIEIAKKAAAPGGQFVLGTIGGIRGIRKSTATNAEI
IASVREQAESLLSGDPDGILFETYYDFDELSDSVKLLRTMSDVPIIAQVSMHEPGVLQNG
LSLNEALHRLEGIGADVVGVNCRLGPFHTLQAFEDVTLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGRAAVLLRNEGVRLIGGCCGTTPKHIEAAKKRLVGLPPLTEKKVKTKKPIV
IQEAKPSTDVSICEKAKTARTVIVELDTPKTLLTEKFIEGANKLYDAGVDAVTMADNSLA
SPRISNMAMGATLKLQHDVRSLVHITCRDHNLIGLQSHLMGLDALGLHDVLAITGDPTKI
GDFPGATDVYDVSSPELIQLIKQLNDGISFSGKPLKKKANFSVAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVFTKEKIVDVYEATKHLSTPIFIGIMPLTSMRNAEFLHHEVPGI
KLSDETLERMRACGDDQERAAKEGIQIAKELLDTAAQIFNGIYIITPFLRYDMSMELIHY
INELDALKERGIVHADSSN
>A0A7G1LAB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas hydrophila|TrEMBL
MGFHSARQVEALNQSLADLSGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLERPEMYATDLVALLKAEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDDDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQP
>A0A847IN46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetomicrobium flavidum|TrEMBL
MKIKELFEKKRFVFSFEIFPPKPTTPLERIYNTLDELKGLKPDFISVTYGAGGSTRDRTP
QIAIDVKNNYGIESLAHLTCIEATREETCDLINFLIGNGVHNILALRGDLPQGQSAPKGD
FRHAVDLVSFLREKYGQAISIGGAAYPEGHIECEDPIKDLRYLKQKVDAGVDFLITQLFF
DNELFYRFMERADIAGINVPISAGIMPVVNKNQIERIVTLCGASLPQKFVRILHRYADEP
RSLEEAGIAYATDQIVDLIAFGVRGIHLYTMNKAHVARRIVSNVSTLRETMHGPKGEEAL
YEGR
>A0A846KYQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. NCIB 9042|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNAEMETQLWETVAELKKWDPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLSTAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYQ
PHPEGYENAAALVKGLRDIGDFEISVSAYPEKHPESASDAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIAVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A846LDG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. NCIB 9042|TrEMBL
MIIKRIMHKLPDISAASIIPASIEASPAQVLGASDLAGLFPQGVRVYLTDTGAASQERLV
DAAGHLRDLGYEPVPHLAARRIASRTGFEEQVRRLAGEAGVTDVLVVGGGVDRPAGPFAS
SMDMLSSGIFDRCGIRQIAIAGHPEGSPDFNDDTAMAALRLKRDFAERSDAAMRIVTQFG
FDPARFIAWAEGLKASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESIVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGGADRSAS
QDSIAG
>J9E866|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wuchereria bancrofti|TrEMBL
VVIPQACSKKWGESRTDWVANGTYVPLRDRIKKRVAKGIPFFSLEFFPPKTTNSVANFFA
RLDRFREGNPMFVDIAWHFGSDPGNISSETSSSSVAAGCLDYCGMDTMLHITCCPYTKEQ
SIRHLEQSKALGLKNILALRGDLPRQVSLAENF
>A0A6A8TLY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKDQAPQFDIIGACYPEGHPDSANQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLETCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARQIHEATHSLFKHHSQVGAL
>A0A6P2D0U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmata massiliana|TrEMBL
MHIQDIFAQHRTTFSFEFFPPKTDEASEELFRTIAALQSLQPSFVSVTYGAGGSTRDRTH
DLVVRIERDTNLTAVSHLTCVCHSLPEMTAILDRYATSGIENVLALSGDPPKNLANYDRT
KDAFHYAEELVKFLRNRPGANGRGFGIGVAGFPEGHPGCPNRLQEMDNLKRKVDAGADYI
CTQLFFENRDFYDFRERCDLAGIKVPIIAGIMPITSKSGMVRMAELAAGAHFPAKLIRAV
GRCADDDAVARVGISWATEQCADLLHNNVRGIHFYTLNKSDATRQIYQNLGVESSAALRA
G
>A0A5J5J6G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium rhizomatis|TrEMBL
MSVHDGARAPRVPVSFELYPPRSAESAAALHATIDALAAVSPRFLSVTFGAGGSSGGSSL
ELLRHIRSYTSVEPLAHLTCVGNTYAGATALIREFLDAGITSFLALRGDPPLSGDSGIGD
LESAAQLVQLIDRVQAERAPYRESTIPGLPGAARVDSRPRVQIAVAAFPNGHPRSRHPLE
HIDALLAKEAAGATFAITQLFFHADDYFCFVERARTAGVTIPILPGFMPITSPQRLRRVL
ELSGEALPSDLAIDLDVEPTAEGRREVGIRHASRLAAELVAGGAPGIHLYAFNNHDTVLA
VLREAEIIPSIPEQEFAR
>A0A154C622|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp. KX64203|TrEMBL
MKRISFEFFPPKTDEGRTKLLTTQQKLLAKKPAFFSCTFGAGGSTRDNTREMVGKLREQH
ADTAPHLSCIGQSREEILELVRGYRDSGVRRIVALRGDLPSGMGYAQSEVKYADDLVRLI
REETGDHFTLEVAAYPEMHPQARSFEDDIAHFKRKIDAGANSGLTQYFYNADAYGYYMDA
LRRTGCDAPVYPGIMPILNVANLIRFSGVCGADIPRWLRSKLDDIKDDEQAVKAFGEEVV
TRLCERLLAMGAPGLHFYTMNQAQASLRILDNLGL
>A0A1J5EF92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacteres bacterium CG2_30_45_31|TrEMBL
MNFKLPSSIALELVPHSLQGIVDEACSNIAANPLISSINVPEIRSLPIKSYEPTIELLRN
KVRTTPHFRMIDRTSADLLNKLEALIELGLKEVLLIGGDSPKDNPDFCPSGLTTLHAVRS
VKTQFPGLKVYTGLDPFRSSFREELDYAFRKIDAGSDGFYTQPFFSVGMLELWLEQLPKT
EVWYGIAPVYSQKSRQYWERVNKVVFPPDFSYEKNANAELARQLLDKIAEAKQRAYLMPI
AVSAKEYLNSIFE
>V1E3T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella decolorationis S12|TrEMBL
MERRTWAVEEIHMAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRL
EPLNPKFVSVTYGANSGVRDRTHGVIERIQKETNLVAAPHLTLVDASDEELLDLAKHYWK
SGIRDIVALRGDLPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDAANAQADLIN
LKRKIDAGASRAITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTN
VSLPSWLHKQFDGLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICH
TLGVRPKAV
>A0A125WDE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis NM2795|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A419S6Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelobium manganitolerans|TrEMBL
MKITDHIKNAKGKTLFSFELLPPIKGQSIQGIYDAIDPLMEFKPPFIDVTSSREDYIYKE
KENGLLEKVSYRKRPGTIAICAAIMNKYKVDAVPHLLCGGFTKEETENALIDLQFLGIDN
VLALRGDARRTDASFVPTPGGHCYATDLVQHIKDHNSGKFLHEDVSSEHNSDFCIGVAGY
PEKHFESPNLKTDFSYLKKKVDLGAEFIVTQMFFDNQKYFDFVNKCRENGIDVPIIPGLK
PISAMGQLVALPKSFHIDLPEELSEAVHACKNQKEVKKVGTEFMIQQCKELVEFGVPVLH
FYTMGKPEQTYEIAKAIF
>A0A2N4WR00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyrobacter sp. TH134|TrEMBL
MTPTLNQLHEYRTATDTPLFSGLPGDVAVSFEFFPPKSEKMEDQLWDAVTRLKPLDPSFV
SVTYGAGGSTRERTHATVARIIGEAKLPAAAHLTCVAASKAEIREVAEQYWEAGVRHIVA
LRGDAGEPGAPFTPHPEGYASAADLVSGLKAIAPFEISVAAYPETHPDAVSPQADIDNLK
RKLDAGATRAISQFFFSAETFFRFRDACAAAGIDAPILPGILPVTNVAQARKFASACGAE
IPAWMDGLFEGLDEQPAARQLIAATIAAELCRRLYAGGVRDFHFYTLNRPELAYAICHLL
GKRPHNVALAGEAA
>A0A5D3I8X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorella thermoacetica|TrEMBL
MVESKMAKILSQGQFLVSGEIGPPKHADPTEIKKHAALLKDYVDAMNLTDNQTAIVRLSS
IAAGVHVLQAGGEPIIQMTVRDRNRIALQSDLLGAYSLGMRNVLCLSGDHQSFGNHPTAK
NVHDVDSLQLIRIVKDLRDEKKFACGEEIKGQEPRFFIGAAANPFADPFEFRVMRLEKKI
NAGADFIQTQCIFDMERFERFMALVRERGLHKRAKIIAGVMPLKSARAAKYMQQSVAGMI
VPDEIVNRMEKASDPKAEGVAICVELIKHLQSIEGVAGVHIMAVMWEDIIPTIVKEAGLY
PRPKVE
>A0A336NA79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aggregatibacter aphrophilus|TrEMBL
MSYAKEIDNLNQHLANLNGKINVSFEFFPPKNEKMENLLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLEAAPHLTGIDATPDELREIAKDYWDSGIRRIVALRGDEP
PGYSKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDVGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMASVTNVSIPAWMAKMYEGL
DDDQTTRNLVAASIAIDMVRVLSREGVKDFHFYTLNRSELTYAICPILGIRPTL
>A0A0Q7SHH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Root52|TrEMBL
MKADLRSVMQERVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
FETNTYSANYDKLSKFGLESKVESVNRAGVRIAKEVAGSQGYVLGAVGSIRGGKRTNVST
SELKRFYEQQIFALLDEGVDGILLETFYDIEEMDIALLQTRKLSDLPVIGQFAVEHVGHT
LDGYTMPEAFRIMREQGADVIGFNCRTGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GEFRYGATPEYFGQTAVQFADLGARIIGGCCGTTPDHIAAMAGALADYQAAPIVQPDLTD
PKPRIVLHEHVDERAGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAEVLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPIYDPQLIVAMHEATKHLEIPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATMYFKGIYLMTPFMFY
NMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A6J5FHA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia caffeinitolerans|TrEMBL
MKPIELSFEFFPPKTPDGVEKLRATRAQLLTLKPRFVSVTFGAGGSTQQGTLDTIVEIAK
EGVDAAPHLSCIGSSKESLREILRQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IREETGDAFHIEVAGYPEYHPQSRSPRHDLEAFAKKVKAGADSAITQYFFNGDAYFRFVE
DAKKLGVDVPIVPGIMPITNYTQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTDLCRRLVEGGAPGLHFYTLNAAGATKAICERLDL
>A0A6A6NK78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hevea brasiliensis|TrEMBL
MQMAEENPTTTGSFSPSNSSLPRPRMVSTTSLRGWTEWSLTTHLSCDITWGAGGSTADLT
LDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQ
VEGGFACALDLVKHIRSKYGNYFGITVAGYPEAHPDMIGSDGVATPENYQKDLEYLKRKV
DAGADLIITQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKVCI
PPYRYQLRLVLQEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAIL
MNLGLIDESKITRSLPWRRPTNVFRAKEDVRPIFWANRPKSYISRTLSWEQYPHGRWEDS
CNPSYFMRARARDKKLHDEWATPLNSIEDILEKFKKHCLGKLKSSPWSELDGLQPETKII
NEQLGKINLKGFLTINSQPAVNGERSDSPSVGKLGGPGGYVYQKAYLEFFCSTDKLQVLV
DKCKSFPLITYMAVNKGGTLVSNVGTNDVNVVTWGVFPAKQIIQPTVVDPASFNVWKDEA
FEIWSRGWASLYPEDDPSRKLLEEVQSGYFLVSLVDNDYIHGDIFAVFADL
>A0A1Q7G4T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_40CM_56_16|TrEMBL
MQDLLTRLENHVLVCDGAMGTMLYSKGVFISRCFDELNISNPELVREVHLDYIKAGADII
ETNTFGANRTKLMTHGLADQIRHINIQGARIACDIAGDNILVAGAIGPLGIRIEPWGKTA
IEEAQVTFREQAKALVDGGVHALILETFFDLNEVYAAIRGVRDVTDQPLIVQMSIEEDGN
SLEGTPPEVFAKRLEEWGADVLGLNCSVGPQIMLDAIERIANVTSKKLSVQPNAGKPRNV
EGRNIYLGSPEYMASYAKKFVQYGVRIVGGCCGTTPQHIKAIRAAVKSVGVAVLGPSPGA
SRRPLPAGEGTEGESSIPLESRSRLGRKLATKEFIKIVEMIPPIGHDFAKAIEKAKYLQA
QDVDAINVPDAPPSSARMSAISLAVLLEKSTEIESLAHYTCRDKNLLGMQSDLLGAYALG
LRNLLLITGDPHQIGEHSDATAIYEVDSIGLTNMVSRLNGGVDVGGKSIGKPTGFVIGVG
ANPGAMSDLELKRFFYKVEAGAEFVLTQPVFDATVLERFLDRAGNSKIPVIAAIVPLPNY
KTAEFLNYEIPGCSIPDSILERMREAQSKSPEHARNEGILIAQEILERIHGTVQGVQIRG
PFDRYETPVEVLSVPMKGATR
>A0A6L7KJH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boseongicola sp. SB0667_bin_21|TrEMBL
MPLPNLSFEFFPPKGIRASCRLWEAVSELAPLDPDFISVTFGAGGAQCDLTLDTVMTIME
QFDLAVAAHLTCCNATREETLAVAESYSAAGVREIVALRGDPPSGTDTFRPHPDGFKDSC
ELISALGGLNRFRIRASAYPDPHPEAPSPHADVEWLKRKVDAGASSAITQFFFEAESYFR
FRDACDAARIDVPIIPGILPIEDWTRMKNFAKRCGAHVPAWLADAFETALRDDRHDLLAI
SVCTELCSDLMEGGVENLHFYTLNKPYLTREVIRALRTARTTASLRHVA
>A0A143BAH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp. DDH964|TrEMBL
MSLLQQQLAAGSFVVTAEIAPPKGCDVGEALAKAQQLSGVTAINVTDNQGANMRLSPLAL
AGMLVREGFEPILQLTCRDRNRMALQADLLGAAALGIENLLLLSGDHARFGDHPQARAVF
DLDSVQLLQVADGLARGSDMAGKALRGTPRFFAGAAVTPEAEPFELMFQKFDKKIKNGAR
FFQTQAVFDTYRLKTFMAAARPLGVPVLLGVLLLKSARMARFLNDHIPGVRVPERLIARL
EGAADPRAEGVAIARELVAAARAECQGVHLMTLGGEELIPEILG
>K5ZYK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides johnsonii CL02T12C29|TrEMBL
MKVIDLINSSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQKTDIYHEHATDLQQQVNDFNKGIAIDGSAFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDDEAKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVYKVAKEVY
>A0A2D5Y441|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micavibrio sp|TrEMBL
MTKPTISFEYFPPKSEKAETALWDAMDKLAMLDPAYMTVTYGAGGSTRDGTLATLKKARD
RFGIPLASHLTFINTTKDDMYALVDELWDENIKHIVALRGDMPGDLQWPLENDENYFQYT
SDFVAGLVARHPFEISVGCYPEKHPDAPSMDDDLRALKLKCDAGATRAITQFFFDNDLFY
RFRDQCEKIGIETPIVPGLLPIHDFKSMCNFAGKCQASVPDWLHGRFEDVSDEDAHKIAL
DLLVGQSEDLAANGVEHIHYYTLNKADMTTEACVALGYKAKAAA
>A0A1C9WR27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. U41|TrEMBL
MGNEAVARVRLEVVPSADLLTALPLVFDPPGSVSVTCLPHHGPERTVEASTCLARLGYHA
VPHLAARSITSKAQLHSLLLELQEAGVSELFVVAGDRRTPAGPYCWSGQLLEAVKAYSAD
FSVGIAGYPEGHPHLGQDKLLSSLEIKAPMASSLVTQMCFSAEAISNYLRTIRKNGVELP
VWVGVPGPVSVKKLVSMGARLGVGRSLKLARSSGMAGALWQRGDFMNYDSGRLIREVHQE
LAGDPLFAGFHVYTFNGLGRLPGLLDSLPKLQEAATKPPSKSGPLFPAQI
>A0A031FNZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium oleivorans|TrEMBL
MSIIQTPSVTSVPVSFEVYPPRDDAADAALHETIAKLAAVDPSFISVTYGAGGSTGGRSL
EVLTHILRETRVEPLAHLTCVGSSYREAASLIREFLDAGVRSFLALRGDPPEGGGAEARG
DLESAAQLVQLIDRVQAECSPYTEEPIPGVPGAARVERRRHVDIAVAAFPNGHPRSRYPA
EHLDALLAKQAAGATLAITQLFFHADDYHAFVARARAAGVEIPILPGIMPITSPSRLRRV
VELTGEPVPGTLAVDLDVEPTVEGRREVGIRYAGELCRAVLEGGAPGIHLYAFNHHRTVL
ATLAEAGVIPPIEETT
>A0A3E4SHS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHTHATDLLKQVNQFNEGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDDDAKQLGIEWTTAQVQDLFEHGYNNVH
FFTVSAVDSVKQIAKILF
>A0A1V4BRG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa KW|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQIACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGSLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFDRLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A3M5JL70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. mori|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A385SZE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseolinea soli|TrEMBL
MFLDKIKKRKSGILLYGITPPKAQTPVEKLPSIAEKSLKTLCGLDIDALIVYDVQDESTR
TNEERPFPFSSALDPFTYTSQYLQALTVPKIIYRPASMFSKAELTEWLNALKSNGFYPVF
VGLPSPDFVPKTTLTEAYEIWRQDHEAHSVIGAVTIPERHAILKDEDVRMMDKVNCGVSY
FISQCIFNVQYAKQTLDALVNTCQARNRELPTIIFTLTICGSLKTLDFMEWLGIHVPEDI
KQELKVCSNPAGRSVEIATEIAKDLIQYCQERAIPFGFNIESVAVRKEEVDASLELLETV
NRLLKVNGLRNESTLRVNSNLS
>A0A067DZ70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrus sinensis|TrEMBL
MAWRTCSSGWTAWWPTTRHSATSRWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMP
VEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGI
TVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDC
RQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGA
EMCKKILAHGIKTLHLYTLNMEKSALAILLNLGLIEESKISRSLPWRPPTNVFRVKEDVR
PIFWANRPKSYLSRTVGWDQYPRGRWGDSRNPSYGALSDHQFMRPRSRDKKLHEEWAVPL
KSVEDIYEKFKNYCLGKLRSSPWSELDGLQPETKIINEQLGKINVKGFLTINSQPAVNGE
RSDSSSVGWGGPGGYVYQKAYLEFFCSPEKLTALVDKSKALPFITFMAVNKEGNWKANVN
QTDVNAVTWGVFPAKEIIQPTVVDPASFKVWKDEAFEIWSRSWASLYPEGDSSRKLLEEV
QSSYYLVSLVDNDYINGDLFAVFADL
>A0A6M7VPJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. NZP2234|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILNETSLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A0C2RDA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jeotgalibacillus soli|TrEMBL
MKLIDALQERILIADGAMGTLLYSYGTDQCFEELNLSAAEHIQQIHTAYIQAGANVIQTN
TYAGNYHKLERYGLEDYVKEINRAGVKNARQAALADTFVVGTIGGIRSLNPQTVKLEEIK
RSFREQLYCLLLEGVDGILLETYYDLEELSTVVSIARKETDIPIIAQASLQEVGVLQDGT
PITEAFKQLEDLGADLVGLNCRLGPYHMLRTLEGVPLPKHAFLSSYPNASLPSYSDGALQ
YNNNAEYFREVAHSFQTQGVRLLGGCCGTTPDHIRAFSEALKGAVPVLEKDVYIQQPKIE
VSSRRIYVPEPLQNIVTKRSSIIVELDPPKKLNIDAFMKGAKALKEAGADAVTLADNSLA
SPRVSNESLGHLIKAEHDVRPLVHITCRDRNLIGLQSHLMGLHTLGLHDVLAVTGDPTKV
GDFPGATSVYDVSSFELIEMIQQLNRGVSMSGKDLGESTSFSIGAAFNPNVRSVERAVLR
MEKKIKAGADYFMSQPVFSEEKLLEVYEYVKDINAPLYIGLMPLTNSRNADFLHHEVPGI
KLSDQVRERMATVAGDKERSSQEGLAIAKSLIDTALELFNGIYLITPFMRYDLTVELTKY
AKQQAAKRAGGVNHVSNIIH
>A0A424KVC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillales bacterium TMED33|TrEMBL
MKTFDPKGKPKSWSIEITPKESKTISCFSTFLDCDTKVNVTNLPKTSVTDIFATVEKLKH
DGMNPVPHITARTVIDEDDLARIVEKYATLEVSEVLIIAGNKFQPAGSFSSSSDLISSGV
FEHFGIINLGVAGHPEGSPDITQQQLEDAIDQKNHLAASRGLNIFLETQFCFDAQRIIDW
EKAIRDRGNSLPIRVGVAGPTKLLSLINFAIKAGVGPSLKFLIKERDKLTKLVHSYDPTD
LILSLAPQFSPEANTCLESIHFYAFGGFRKTAEYAQELFK
>A0A3N9XZ35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora ureilytica|TrEMBL
MALGLPSTLPNPQPAIGELIRERQPTFSFEFFPPKTEAGEQLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVVGRLAGVGVRNVLAVR
GDPPGNPGGEWIRHPEGVDYAEDLVRLVRNAGDFSVGVAAFPYKHPRSPDVASDTAQFVR
KCRAGAEFAVTQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQFSTIERSVQLSGAPF
PRVLAARFERVADDPDAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARV
>A0A1Q3V413|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium 69-11|TrEMBL
MSDATLEDPKPILRRWLSGERVGPLPVRSAEQAPPKLSFEFFPPRTEALEQQLWTCIRRL
EPLAPRFVSVTYGAGGSTQARTHATVARLVQETSLVPAAHLTCVGATREEVDDVARAYWD
AGVRHIVALRGDPPPGTEYAPHPGGYPYAADLVAGLKRIADFEISVAAYPETHPSAQSPD
ADLDNLKRKLDAGATRAITQYFFDTSVYLRFLERCLAAGISAPIVPGIMPVSNFAQAAKF
SAMCGASIPPWLGQMFEGTEDDAEIRRMVAAVVAAEQVRVLQANGVDEFHFYTLNRPDLT
YAIAHILGVRPLRKLA
>F2PWP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton equinum (strain ATCC MYA-4606 / CBS 127.97)|TrEMBL
MHIKDKLALAEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMSREKVDDALQSAFKAGCTNILALRGDPPREKEA
WEQTEGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFLDWVKKCRQAGIKVPIIPGIMPISTYAAFIRRTNWVKCAVPKGWMEAL
EPVKNDDAAVKQIGKALVSEMCRKLLENGINHLHFYTMNLAQSTTMVLEELNLKPSTETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSVRDLSDIFVRFLEHKLDRLPWSESAITQESEIIKDDLID
LNNRGFLTINSQPAINGAKSSHPIYGWGPRNGYVYQKAYLELLISPALIDEVIRRIESNA
DLTYHCINKDGELKTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSASRKLIQNTMDTWYLVNIVNNDFHKTHDIFDLFKGLVLKDIDTEVSGTQQATE
LAENGTHSEAPASKSEKQAVSAN
>A0A4S1HAE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.168.01.1.1|TrEMBL
MRSETARRDGDIRLSFEFFPPKNAEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPTL
DAVRRMIGDSHLATAAHLTCVDASRDEVHQVVDEFRNAGVRHFVALRGDPSTGIGTAYQP
HPQGYENAAALVKGLKELGDFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQF
FFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPAFLDERFEGYDE
DLEGRARVAAEVAAEQIADLQRRGVSEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A4R5N7V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc fallax|TrEMBL
MKISAYYQLTTRPLISVELSPQSNSQNHMSASMVLSALDLNQLPIDYVSITNHMGTSDDG
VAQLAHHIQMQYHMPVLQHLPAVGQTPHTLPDQLSHLVQQGIQNLLVIRGDGEAESGSFT
SSVALIETIKATHDICVGAAIHPQHILDNPKKGLENVEAKIAAGTDFFISQMFFDNRDFL
RVVELLRQHDIQVPIVAGIMPITNAEQLKWVPKMTGQPVPDQLMTLMSKHQSASQLEMAG
IDYAAQQIKALIAHDVDGIHIFSMNQANHLQKLLTAIV
>Q3ARK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium chlorochromatii (strain CaD3)|TrEMBL
MLVKEILSAANNPVFSFEFFPPKKDEEWDTLFKTIAALSPLHPSYVSVTYGAGGSTRSRT
HNLVTRIQQETGLTVVSHLTCISSEESDTEAILRNYQENGINNVLALRGDKPTGVATLQE
AIKDFPHAIDLVRFIKRNFPDFGVGVAGFPEGHPETPNRMQEIEYLKAKVDAGADYIVTQ
LFFDNRDYFDFVERCQLAGITVPVIPGIMPIATKKGMIRMSELALGSRIPAPLIKQVLAA
ENDSDVAAIGIEWATAQVQELINQHIRGIHFYTLNMADATLKIFRNLSA
>A0A561VAI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora dendranthemae|TrEMBL
MASELRRSLDRMRYEVLPVGDAHVEELEPGSTVTVTASPAKGIGPTLDTAERLAARGLHA
VPHLAARSIRDRAHLAWVLDRLDAAGVSEVFTIAGDSTRPLGEFADSLSLLRAMERMGRL
PSRIGVAGYPERHALITDECAIRALSDKSVYADYVVSQITFDPRTIADWARDVRLRGVRA
PVYVGAPGVVDARRLLRIAMRIGLGESTRFLRKQYDAVSKMLARYTPEDLFDELSTQLTD
PDSPIAGWHLFTFNEVTKTVRWRDDLAARLSGYADRPA
>A0A2U8E2K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ereboglobus luteus|TrEMBL
MTANRPISELFAQKRPLRSLEFFPPRDDAGVENLRAAAEALRRINPDFVSVTYGAGGSTR
ERTTQVSAMLKTDFGLTVMPHLTCVGHSRDELNELADRIYENGFRNIMALRGDPPKGSVE
FKPAPNGLRYANELVALLKARHADLCLGVGGYPEKHPEASNEDVDLDNLKRKVDAGASFI
TTQLFFDNTVYYRFVEKCHARGITVPVIPGIMPVLSLKQVRRITQLSSAYLPPALIKRLE
AAHDDADTSEMIGIDWALTQIRGLLANNAHGYHLYILNRARSALALAAGLAA
>A0A1H5S855|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospira multipara|TrEMBL
MNLKSFLKDNRLMIDGAFGTYYNNLFDTNELPEFANITNKDRVINIHKEYIEAGAKLIRT
NTFACNSISLDTSNDRVKDYIRAAISNARTAIKLAKKEANKEDELGDSDTFLAASIGPIP
FSDLMDREMLTKEYLEIVSAFIEEGVEIFDFETFDSLDYIMEAIKLASKHGEVLVSFSVN
QYGYSNAGLSARHLLEDANNCEEIFATGFNCGVGPSHMEAIIKKLSYMITKPLITVPNVG
YPSNVSGRMVFLNQNVDYFKERIDNLLDCGVDIIGGCCGTNPKHIKAIAKDFDFKGKVRN
NDNKVKETRKEAVTDAAFYNKPNQASGKLIAVELAPPLNGDDEKLISSALYLKNKGVDVL
TFPDSPSGRTRADSILVANKVNIETGMCVMPHICCRDKNAIAIRSQLLGAYVNDIKNFLV
ITGDPIPSIVRSSVKSVFNFDSVGLMNIIKDMNCDQFNQSQMVFGGAINQGRSNFKVELN
RVLKKLEAGATFFFTQPIFSKEDIDRLRTIKEAVGDRAKILAGIMPLVSLKNASFMKNEM
AGINVTDEIISMYREDMTKEEGEEVGIKVAKSVISQTKDFVDGYYFSFPFNRVYLLDRIV
SDEL
>A0A3M9L7Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus euhalobius|TrEMBL
MPSAFKEKLLSDEFIVTSEISPPKGVDVSSVFEEAGLVRDYVDAFNVTDNQRAVMRMSPL
AMGHLLKEQGLDIIMQFTCRDRNRLALQSDLLGAYAMGMENVCIMSGDYPTKGDNPGAKP
VYDLDSVQLLGTINRLEKGFDIAGNPLESVPSFTKGAVCNTEPDLPLQLMKLEKKARMGI
DFFQTQAVYDIGHFETFMDSISHMEVPVLAGLIPLKSAHMARFMNEKIPGIQVGDELIAR
MESSTDPAEEGLLICAEQVRELKKVCRGIHLMPIGHYRQITALFEMAGLYEKD
>A0A8J6QJW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aestuariibaculum suncheonense|TrEMBL
MKVTDHIKKANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVD
KGNGLLDKRITRMRPGTVGICASIMHKYNVDAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VVALRGDSRKDESYFVPTKGGHAYASELVQQITNLNEGKYLHDEIEVEHNYDFCVGVAGY
PEKHMEAPSLNTDLKRLKEKVDAGADYVVTQMFFDNKKYFDFVEKARAIGINVPIIPGIK
PIAVKRHLQILPQVFKIDLPEDLIDAVEACKDNNAVRQVGIEFAIQQSKELKEAGVPFLH
YYSMGKSDNIKAIASELF
>A0A8J6MCK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flintibacter sp. NSJ-23|TrEMBL
MKLAELFGKGRTVFSCEVFPPKKTSPVDSIYKTLDGLRDIHPDFISVTFGAGGSQVNQST
REIAGLIQNQYHIPAMAHLTCVAAGREDVDRLLEELKAEGVENILALRGDVNPDIPPKTD
FAHASDLVSYIRAHSDFGVSAACYPEGHLESPDLVSDIRHLKEKVDAGAQHLVSQLFFDN
EDFFRFLERARIAGIDVPIEAGIMPVLSRSSIQRMVSMCGASLPSKLTRILARYGDHPAA
LREAGIAYAIDQISDLIAGGVEGIHLYTMNDPAVAQQIAGSLTSIRSV
>A0A8B9DZZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anser cygnoid|TrEMBL
QLKNASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDRWFSLEF
FPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLET
ILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVKHIRN
EFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFLKFMKDCQ
AIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVS
MCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVEDVRP
IFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEE
LTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINS
QPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNYHIVNVK
GQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESP
SRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPAQQ
>A0A2U3CJT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heimdallarchaeota archaeon (strain B3-JM-08)|TrEMBL
MIEREKFQPSLSVEIEPPHIHSNELEHSEISKFSYLIRQMASSIDFISVTNRATFRLSSI
STMKLISTVLRNSNHAAITYPVQHLTTRLSLHDTFNELLDARRLGIEYLLPVLGDPRGPK
VSGFFNNSLELLTFIKGVTNPDLYSSLSNQIPSMKTVDVPYIDDGNFIVGSVIDPNEFKE
SANGSKRRIRKQQIELFNKRRDLGADFFITQGLFDPLQFLNFKDEIDCKDIPIGVGVIPP
SFTIANVTGIPLSQEIKTRLKQKTSKKQQFQVALQIAHENYCTLRENGVPWIHVYGLGRY
DVFKMITEGTPTVKE
>A0A2K4FB51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus argensis|TrEMBL
MTKLLHKLQTQVLVGDGAMGTILFTEGLDTCPEAYNLTHPEKIEAIHRSYIEAGADVIQT
NTYGANFEKLKAFGLEHKVKHIHQAAVAIAQRAAQPETIILGTVGGFRSVTQEDLSLSTI
LYHTELQIETLIQSGVDALLFETYYDLEELTAVVKLAREMTDRPIIAQLTASNTHYLKDS
TEINRAIQHVVECGTNIVGLNCHHGPHHMQQSFSHIDLPQDAYLSCYPNASLLDIENQEI
RYSDNAAYFGKMAQKLINEGVRLIGGCCGTTPEHVRYIKQAVKDLSPVTRKNVIPIKKRE
RNQLAPTRKKNLTSIVKQRPSIIVELDTPKHLDTSTFFDNVEQLDQLGIDAITLADNSLA
TVRISNIAAASIIKQQYNLEPLVHIACRDRNLIGLQSHLLGLSLLDITEILTITGDPARI
GNLPGATNVYDVNSRGLTEMALRFNQGINTDGAELKQRTHFNIAGAFDPNVRRLDHAVKR
AEQKIKHGTHYFITQPVYSSAKIQEIYEATQHLETPFYIGIMPITSYNNALFLHNEVPGI
TLSDDILEQFEAVKDDAAQTKALSLKLSKALIETVHRYFNGLYLITPFQRVDLTIELAHY
SQTITSTKQEALS
>A0A2A5BTT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrionales bacterium|TrEMBL
MTKDWLLSFEFFPPKTQPGAEKLARTRETLAQLAPEYFSVTYGAGGSTRDNTRDVVLETR
AAGLDVMPHLSFAFGDDDANAIKALLETYSEAGVSRLLALRGDLPSDPENTRKPIHANEL
VAFIREHFGQQFALQVAAYPEIHPDAKSYNDDIYWLGEKFKAGADGAITQYFFNIDAYWH
FLEQATKAGIDKPIVPGIMPITNFTNLARFSANCGAEIPRWMAKKLEQYGDDQASIIAFG
ADVVTQLCERLLEGGAPGLHFYTMNQAEPSVDILSRLGISPEQS
>A0A3D1ZPP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrionales bacterium|TrEMBL
MISANARSISFEFFPPKTKQGHAKLAETRLALAALEPEYFSVTYGAGGSTRDNNKNVVLD
GLNAGFNTAPHLSFGGDEADTIIALLQEYAAAGVNRLVALRGDLPSGFGGGARLVHANEL
VGFIRQHCGEQFHIAVAAYPEIHPEATSYDTDIGFLKKKFDAGASSAITQYFFNPDAYAY
FIDQCQASGIEQPIYPGIMPITNFDNLLRFSKNCGAEIPRWLCYRAEALQHKPAELNAFY
LEFVSQLCEKLIALGAPGIHFYTMNQAEPSIAICQNLGLQ
>U2EPH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinisphaera shabanensis E1L3A|TrEMBL
MTHVSQNSFSIEFFPPKGPKGAARLDKARTRLATLGPDFFSVTFGAGGTTRSGTLETVNR
TMETTGIPTAPHLSCIEGTHDSINELLDSYKAAGVERIVALRGDMPEGMEKPGVFSYANE
LVAHIKQRHGNDFHIEVGCYPEYHPQANSPADDIDNFVRKVQAGADSAMTQYFYNADAYF
NFVEEVAAQNIDIPIVPGIMPIVDFGQVSRFSAMCGADIPRWIRQKMEGYGDDKASVQAF
GREVVARMCEQLLAGGAPGLHFYSLNKAQPTMDLWQDLGLPTPSSRTAEAG
>A0A090FRZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. SOD10|TrEMBL
MSVRHQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVF
LGCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKIFLL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVA
GIHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAQRLDHILHDEITETQVDMV
KTAH
>A0A0C2QD18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolypothrix campylonemoides VB511288|TrEMBL
MLDTINPTALTSFRTAAKTGQFLITAEVAPPKGGNPEHMVRMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQNGIEPICQLACRDRNRIGLQADLMGAHALGIYNILALTGDPVKA
GDHPDAKGVFDLEAVRLLQLIQKLNHGVDCNEKPLTDGALDLFPGAAVDPQCASWSGLQS
RFERKLAAGAQFFQSQLITDFDRLEKFMDTIAAGCNKPILAGIFLLKSAKNAQFINRCVP
GVNIPDHIIDRLAQAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIVPILDMAGV
APVNLVVTK
>A0A7Y0EWW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium sp. DSM 109959|TrEMBL
MHTPMFSLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHTDRTATARIAHTIR
NEYGIPAVAHLTALYSDKAKVDEALDMFEQAGVEAVLALRGDYIEGEETVGVFEHASDLV
AYIRERKPELKVFGACYPEGHYQAESLDQDIEYLKVKVDAGVTHLISQLFYDNDDFYRFI
DKARAAGIDVPIEAGIMPVRGAKSVRRMAERNASRIPEHLAVMLDKWEGDGEALRAAGIA
YASQQIADLVAHGVDGIHLYSMNHPASTRRIWHNVQPLFGE
>A0A7X9TED0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flammeovirga yaeyamensis|TrEMBL
MKVIDRLIQAEREKKTLFSFELLPPVRGKSIQSLFDAIDPLMEFNPAFVDVTYHREEYVY
KELPNGLFEKSVQRHRPGTVAVCAAIMHKYNVDTVPHIICGGFSKEETENILIELNFLGI
ENILALRGDAAKGEAAFTPHPKGYKYASELVEHVDQLNKGEFMYAESGFKGGFCMGVAGY
PEKHMDASNLDTDIKYLKQKVDLGAEYIVTQMFFDNQKYFDFVKRCREAGITVPIIPGLK
PLTTKRQLTLLPNIFKLDFPQELIKEAEKCKDNKAIKQLGIEFGIQQAKELMEFGVPSMH
YYSMGRSTSVKDIAEAIF
>A0A4Y8PHE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylacidiphilum sp. Phi|TrEMBL
MATLIERLNESLLIGDGALGTYLYSLGVPRNYCIEELNLSQPYLVEKALKDYIDAGSQII
RTNTAEANLYYLSFFKLENKIKEIIGKSIELARRALGSREGWIAGTVSPIWIKPADPPID
LSTRRHLYEEQISLLLEGGCDLLFFETFTDLSDLLLALELARNKGARLIFAFVASFEEGK
LASGESVGEAFSKLREAGASLVGINGATGVQASIHLLEEIEKKENELLGVYPNAGKPEFY
EGKLTYSASPSYFGQNVLRFVEEGVCLLGGDYGTEPVHIAAMAQAAVGLKPVKRKAPKLR
LRYEVSEKETLPQVEESLLERLNKKPIFLVEYDSPKTLTMGKFIEGVKAIERAGADAITL
ADNSLAILRVSNFAAAIHVRRVSNLIPVLHVACRDRNLLGLQSELMGLGTLGFRHVLALT
GDPAKSGDHPGATSVYDLNSIGLIRLLSGLNRGVNAAGKDLKGKTDFIIGCAFNPNTAQF
DVQVRKLEAKLAAGASFVMTQPVFDFELVKKIFSYLKPLGIPVFVGLMPILNYRNAEFLH
NEVPGISIPEEIRNRLRKLEGEKATETGVEFAKALGEQILSHFNALYLITPFFRYDISVR
LLESLHAKAPV
>A0A6G3TTP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rubrogriseus|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTHFVD
KCRAGADYAITQMFFQPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A848ZAQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Inquilinus sp|TrEMBL
MSHEQPDPGSAPVRVSVEFFPPRSPQMETTLRDCATALQGLAPAFASVTDGALASDSEMT
PAIVLGLAEETSLDLAAHMTCVARDRAATEALARTYWRAGIRRIVALRGDRADAGPYRPD
SAHYAYAVDLVDGLRRVADFEISVAAYPEVHPDAPSAAYDLDNLKRKLDAGATRAITQFF
FDNSAFLRFRDRARTAGIEAPIVPGILPVTNFERAAEFARRCGTRVPDDLAGRFAGVADS
KEARRQAAVDFAVDQGESLRAHGVDAFHFYTLNRAEPTVTICRHLGIAPASRAVRAVASA
R
>A0A355VTN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Holosporales bacterium|TrEMBL
MQATFNNKKEPVFFSIPSLRSNPLELRSLDKFDKSSLIPHIRCKNYSQEQTIEKANLAKE
MGFKKIFLVSGDTPYPHQNGLTSCQAIPYYHRLDLEVGSSLDIYAPCLRTEIEKALEKIK
SGASYLVTQVVFFSNETEKRLLKIQHALQDTGVKIYPCLSLLGDFEKDRHLLKKICPSLP
QEIFSGKQKIENNNKKAVDIFQRLFNSDTTYLFQVKTS
>A0A0S8DLY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira bacterium SG8_35_1|TrEMBL
MNLKTESKLEKILAAGHLAVTSECGPPRGSDPEVIIKKGDLLKDYVDAINVTDNQTSVTR
LCSMAACIHLKLMGVEPVLQMVTRDRNRIALQSDILGAASFDINNILCLSGDHQVFGDCP
EGQNVFDLDSMQLLQTVRHMRDNGKFLSGDEIKRPPGMFVGAAANPFAEPFKIRVPRLAK
KIAAGAEFIQTQCIFNLKKFEEWMSGVRERGLHEKVYILAGVTPMKSLGMARYMKKNVPG
MDVPDEIINRLAGVPKEKQADEGINICLETIARLKEVKGVSGFHIMAIEWEEKVPEIVER
AGLYPRPDK
>A0A540VR22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spiribacter salinus|TrEMBL
MLPSNEATLAETPDRRAEIAQAALGFSIESMPRDAARITDFRDHLPVGTEVYIAWPPRAD
LDEMIQAATKLHEQGMIPIPHVAARRVESQAVLRDFVQRLTEEAGVKRLLLLGGDPDTPV
GPYPDASSLLTSGVLSAFGIEAVDIAGHPEGHPVMQGDEPAQVLQEKIALARQAGIAVRV
VSQFVLEPDAVVDWHTQTYREAAGDTALQIGVPGVVSTRRLLQLASSCGLSGSLGMLRKS
GRRLAKTAMGHDTTEVLVASLAHLVNAEKSVAGFHFYSFGNFEKTAAWACSVTRGDFDIK
GDAIQLN
>A0A540VUP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spiribacter salinus|TrEMBL
MRLLPRRRAIARWRHASRWWRTRATARRLQGADMARPPLASSPTATPVRRSERHTMATTT
GYEALATPRFELIPIRGMLDAAGHLPVGSVINVTCSPKHGLERTLDAAQALAALGHRPIP
HIAARLVRDQAHLDRLLDQLAQAGMDEVFVVGGDAAKPAGDFDGAAPLLERMANAPQRPS
TIGLPAYPEGHAIISDDALATALAAKREFGDYLVTQICFDPARIRTWLGEIAAGGTHLPV
YIGLPGVMDPKQLLSISLRIGIGTSLRVLRRNQGMTDQMLGGAYVPDALVKNLLPLFEVT
GEVPLAGFHLNTFNLVPPLLSWQARMLDELTVTEAG
>A0A2G9YNQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG23_combo_of_CG06-09_8_20_14_all_40_11|TrEMBL
MTFKEKIQAGKFLVTSEIGPPKGIETKIILEDAELIRGRVDGINVTDLQSSVMRLGSLAV
CSLLKQKGFEPIFQVTCRDRNRLALQSDILSAAALGIENLLILTGDYTTLGDHPEAKPVF
DLDSVQLLQVVCKLQEGFDMNGNKLEGALPKFCVGAVVNPGADPIEPQIMKMEKKIEAGA
EFFQTQAVYDIKVFENFLSKIKHLKTTILAGIVLLKSAGMARYMNKNVAGVTVPQDLIDE
MESVSKEDRQKKSIEIAAGLIKQLKPMCQGVHIMPIGWNKEVPLLLDAAELGGRFSPTIC
AT
>F4T6H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli M605|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2S5QYY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp|TrEMBL
MKQNLPLSFEFFPPKTADGISNLRETRAQLAQYNPEFFSVTFGAGGSTTDRTKETVFEIQ
AEGYQAAPHISCMSSSKEEIRELLSAYKAKGIKRLVTLRGDVPSGEVSVGDFKYANELVS
FIREYSGDWFHLEVAAYPEFHPEALSAAKDMANFKRKVESGADSAITQYFYNADAYFRFV
DSCEADGITIPIVPGIMPIYNYTQLARFSGVCGAEIPRWLRLRLEAYADDLPSLRALGVD
VVSELCETLLAWGVPSLHFYTLNQAGTISKIIDNLELK
>A0A0M4HI22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MSFLKSTYYQDIMNQKLNNLNKKIQCSFEFFPVKSIDLENKLFSSVVKLSQLKPFFFSVT
YGANSGERKKTYEIVKKIHEKTGVITAPHLTCVDSTSNEIEKIAKFYWSNGIRSIFALRG
DSHNTNYLHTMYAYDLVVLLKKIADFDISVAAYPEKHPESKSTRSDILNLKKKVHAGANR
AITQFFFDTETYLRFRDNCLKNNINVEIIPGILPIYNFEQLKRFAKMTNVSIPSWMFEIF
HGLTNDLITQRLIGASIVIDMIKNLSIEGVKNFHFYTLNQSDIVYSICHLFGFGSD
>A0A7Y0AF41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter polaris|TrEMBL
MKVTEHLARAHGKTLFSFEVLPPRKGENIHSLYANIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRKRPGTVGICAAIKNRFDVDTVPHLICGGFAKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFQPHPDGHRYACDLIGQISELNHGRYHDHDEQYQPQGAEPVLCTDF
CIGTAGYPEKHFEAPNLGSDIRFLKDKIDRGADYIVTQMFFDNEEFFKFERRCREAGITV
PIIPGLKPLTTKAQLTALPRAFFLSIPEALAEAIHQAKDNAAAREVGIEWCLHQSRELMA
HGVPCLHYYSMGKAEAIRRIAAGLF
>A0A8C9C2C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocoena sinus|TrEMBL
MTCCHQSREEITGHLHKAKRLGLKNILALRGDPTGDQWEEEDGGFNYAVDLVKHIRSEFG
DYFDVCVAGYPKGHPDAESFEAGLKHLKEKVAAGADFVITQLFFEADTFFRFVRACSEIG
ITCPILPGIFPIQGYRSLRQLVKLSKLEVPQQIKDPVPGASGKRLGAGPALLHPQPRGGA
TTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGR
WGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFKVSAAGWDPWPLA
AETSLMKGGAAAAWNRRGILTINSQPNINGKPSSDPVVGWGPGGGYVFQKAYLEFFTSRE
TVEALLQVLKKYELRVNYHIVDVKGDNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSF
MFWKDEAFALWIEQWGKLYEEESPSRTIIQHIHDSYFLVNLVDNEFPLDSCLWQVVEDTF
ELLSGPPQGKRETEAP
>A0A7C3I4Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meiothermus ruber|TrEMBL
TRQAQELLEAGVPGLHLYTLNKSPATRRVMQNLQIVLR
>A0A7Y7TNR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium|TrEMBL
DCSKVLIGAAALKAAGADAINLAENPLARVRMGNIALARIIQDETGIEVIPHITCRDRNL
LGLQSDLMGASLLGIRSILAVTGDPARLGDQSGASSVFDLNSFGLIKLLADLNSGVNGLG
QPISGSTGFTIGCAFNPNTPKIEVQVARLEKKIAAGAQFAQTQPVYDASLARRMAELTAH
LGIPVLLGIMPLTGERNCEYLHNEVPGIVIPDEVRGRMRGKEKTEGAAEGVKIALELIES
VKDIIGGYYIIAPFGRFEVASELIRAIRG
>A0A2D3HH42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataeibacter xylinus|TrEMBL
MGLTAVELIPRDRETLLRDAGEVSQHFPDAQLINIPDLLRFPLRSWEAARLIRPIFPRVV
PHVRAIDIAPDAPLPGADDPGLREVLVVEGDPPTDLRHRTYPNTSESVIARYRREAPHLD
VYAAFDPYRRAPYKEMQAIERKKEAGAMGFFTQPIFDMRMLDLCMNWLEGETVFWGISPV
IGPRSRSYWETTNHVIFPHDFDPTLEANIAFARQMMDTVAQAGGNTYLMPLRVKLERYLI
PLRRA
>Q5P6B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aromatoleum aromaticum (strain EbN1)|TrEMBL
MHRPELSIEFFPPQTPEGEEKLRATRTALAALKPTFFSVTYGAGGSTRERTFSTVREIAA
DGFEAAPHLSCIGSTRAGIREILDDYASAGIRRIVALRGDLPSGVGDPGEFRYANELVEF
IRTETGDRFRIEVAAYPEWHPQAKNPKDDLTAFRRKAEAGADSAITQYFYNFDAYLHFVD
QVRAMGVEIPIVPGIMPIASFSKLARFSDACGAELPRWMRRKFEGYGDDADSIRAFGLDV
VTSLCERLLAAGAPGLHFYSMNQAGLTTAICERLKLG
>A0A0Q9ZZJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. P11F6|TrEMBL
MSKPAFSFEFFPVKTEQGHEKLLNTYDELNKLSPSYFSVTYGAGGSTRNRTLDIVQALNA
RGDTEIAPHISCIGDDKNEIAELLEFYKTLGIKRLVALRGDLPSGQVGMGELPFSVDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFDLDIENLVNKYQAGADAAITQFFYNADSYLYLR
DRIEKRGIDTVTQPLIAGIMPITNSSNLMRFADSCGADIPRYVRKQLGDFGDDRKAIREF
GFEVVYRLCERLINEGVPAMHFYSMNKIEPNKRLVEELGLTT
>A0A1S8BNH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diplodia seriata|TrEMBL
MHISQKLYEGQKNGKPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPTFVDVTWGAGGRNS
TLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALREAYNAGCKNILALRGDPPREKEK
WEATAGGFRYAKDLVKYIRENYGDHFDIGVAGYSEGCEDQDDPNLLLDHLKEKIDAGGTF
IVTQMFYDVDIFLDWAKKVRAKGITVPIVPGIMPINTYAAFMRRANWTKCHVPPDWLEAL
EPVKNDDAEVREIGKHLIANMCRRLMEAGIIHLHFYTMNLAQSTRMVLEELGLTPDMYSP
LEKPLPWRQSLAPGRREENVRPIFWRNRNRSYVVRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNIKLWGMPKTVRDISNLFVKYMEGKLDSLPWSEQPITSEADVLRDNLVS
LNKRGLLTINSQPAVNSAKSTHPVHGWGPNNGYVYQKAYLEVLVSPELIAELITRIERDP
EMTYYAVNKAGDLKTNAPSDGPNAVTWGVFPGKEIIQPTIVETISFLAWKDEFYRLGEDW
AKCYTSVSPSRYIIEDLMDTWYLVNIVHNDFHIDNGIFALFDGLEVKDLDKEPHGTAESE
VNGHSATNGEAHTNGETKIPDTVVNGNSSSAVQNGTAN
>A0A1W2G7X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reichenbachiella faecimaris|TrEMBL
MKVTEHIANAKGNTLFSLEIIPPKKGENIQNIFDHLDPLMEFNPPFIDVTYHREEYVYKK
HPNGLLEKKTTRKRPGTVGICAALKHRYDVDPVPHIICGGFTKEETENALIDLNFLGIDN
VLVLRGDAIKSEPKFTPEPGGNDYAIDLLHQVKGMNEGKYLDDEMENANPTDFCIGVAGY
PEKHFEAPSLNSDLKFLKQKVDAGAKYIVTQMFFDNQKFFDFEKKCKEIGIDVPIIPGLK
PFKTKSQLSVLPSFFKIDLPDALVDAVEKCKDNKEVQEVGIEWGIQQSQELKAHGVPVLH
YYSMGKSSSVQKIAKEVF
>A0A495FKH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. 93|TrEMBL
MIAANAQGTGFPVSFEFFPPKTPEGADKLRAARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRHSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPEADLNAYIAKVQAGADSAITQYFYNSD
AYFRFVEDSQRLGANVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A2U1UQX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brenneria nigrifluens DSM 30175 = ATCC 13028|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASRDHLREIAQDYWRSGIRHIVALRGD
LPAGGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRVPNWMTAMFD
GLDNDPETRKMVGAAIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAVV
>A0A8E0QLX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus udagawae|TrEMBL
MHVHDMLAENDAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEA
WEATEGGLRYAKDLVKYIREKYGDHFNIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
VITQMFYDTDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEAL
EPVKNDDAAVKEIGKRLIADMCRRLLAAGIKHLHFYTMNLAQATQAVLDELKLIPSEETP
LQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSIRDVTQIFVRYLEGKLDRLPWSDSPISSEANVIKENLVQ
LNSRGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDGLIARIEKNP
DLTYHAVGKKGELRTNTRDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQDMMDNWYLVNIVNNDFHNTYDLFDLFNGLEVKDFDVEVVPDTVETK
SQPNGAAPEEVAVKN
>A0A832JER6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
ALELSQAGADVIGGNCGSGPGYLLKVLRVMAEVTDCPISAFPNLSFPQYMEGRFVYRSEP
EYFAQRAEEIYRAGATLIGGCCGTTPEHIRQLAQRLKGLLPAPRKLVSIRLPEREAPPPR
RRAPFLDRAGKEPILIVELETPRGTLYERVLTGARMMADEGVHAISVAENPLASIRMSSL
VLSYLIQREVGLTAICHITCRDRNLLGLHSELLGADALGVHTILALTGDPISVGGVAGVS
AVFDVNSFGLIQLLRSLNEGQNALGRSIERPTNFTIGVAFDPNRTRLEAEVHRLEKKVAL
GADFAMSQMLYDASRIRQMYRSTRHIPIPIFAGFMPLVSARNAEFLHNEVPGFKIPEAVR
RRMHEAPPGTAWQEGIRIAKELIEVALESGAPGIYLVTPFQRVGMILELVRHVQRVWAS
>A0A7U3LZG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter roggenkampii|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRSIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7C5BMI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
RNRLAMQSDILGAYALGVRNLLCLTGDYQCFGNHPQAKGVFDLDSTQLIQMVKKMRDEKV
FMSGDEMKHEPRMFIGGAANPFGEPFEFRVLNLAKKIEAGADFIQTQPVFDVPAFERWMS
AVRDEGMDKQVYIIAGVMPVRSIKALLYMKESVPGMRIAQDYIKRMESITDKEAAMEEGI
KIAVEVMQQVSKIPGVAGLHIMPVMWESVTPRLVEEAGLLPRPEVPADESFGVSDAAEPV
GGEMEK
>A0A7Y6XWI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKITDHINQAKDTLFSFEIVPPVKGKGIQELFNNIDPLMEFKPPFIDVTTSREQAIYIQK
EGGLEKQITRTRPGTVGICASIMNKYKIDAVPHVICGGFTKEETEYMLVDCQYLGIENVM
ALRGDARREEAFFTPTKGGHTYASELVTQIKNLNKGKFLYESTEDGIFSDFCVGVAGYPE
KHMEAPSLKTDLQRLQHKVDQGADYVVTQMFFDNQKYFEFVEAARAMGITIPIIPGIKPI
AVKRHLNILPQVFKIDLPQDLVDAVDAAKDNKAVREVGTEWAIQQSRELKEAGVPVLHYY
SMGKSDNIYNIAKALF
>A0A7H5FM15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia sp. MM1IDA2H-1|TrEMBL
MTSRLTIPDSSQLPPAERDGNVGRLERVLRSGQFAVTAELAPPDSADPQEVHARAQLFAG
HVDAMNATDGSGANCHMSSVAMCALLAREGHETVMQISCRDRNRIAIQGDVLGAAALGIP
NLLCLTGDGVQVGDHPEAKPVFDLDSLSLLEIVAGLRDKHAFASGRTLTSAPQVFLGAAA
NPFAPPFAFRPHRLAKKIAAGAQFIQTQYCFDLPRFQDFMHRARDLGLLEKCFILPGVGP
LASARTADWMRRHVPGVHIPDDVLARLKGARDQKAEGRDLCIEMIQQLREIEGVSGVHIM
AHRQEAFVPEIIQRAGILGARMPWTPEPRPTPSP
>A0A7Y2Y3F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIERAKGETLFSFEIIPPVKGRSIKELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYDVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNI
MALRGDAMKGEQYFEPTKGGHKYASELVSQIRNLNSGQYLHEVIETDNCSDFCIGVAGYP
EKHMEAPSMKTDLKWLKKKVDLGAQYIVTQMFFDNQKYFDFVTAAREAGIDVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIEEVEKCRNNTAIRQVGIEWAIAQSKELKDAGAPVLHY
YSMGKSDNIREIAKAIF
>A0A6L3VLV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura montaniterrae|TrEMBL
MVVDGFEVICEIEPPVRPDLTRVRHQIGVLSPVADSFLIPDNHIGRATVSSVAVAHEVQA
MGASGIACLNSRDRNLLGFRRDLLTAAAYGVDRFLFVYGDKPTAGGRTSELTVRAMIEET
RAAAEDAAFAGHAPFRVGVASGLRPVPAWKTQADFMFVQVSYSLDALLRWRDGVRLDVPV
YAGVMVLASAGMARNLAAAIPDIAIPDDLVAAVERDRDAGVDAACEHVLAIRDSGAFDGV
HLVPVSRYRQVAARLEHHF
>A0A7C6TB61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MDLHQLLAEGVLVSDGAMGTLLEERGIPQGRAYDLANLTHPALVQSVHEEYIDAGARLIE
TNTYGANRFKLAPHGLGDQVAEINRAGVEIARRAAGDRALVAGAMGPIGRHLVPVGKITH
AEAFRAFTEQAQALLDAGIDLFVLETFADLEELHLAVDAVRSLCSHPIIAQKTFIEDGET
LAGGLPRRVIEEVSRWDIVAFGANCTVGPQRMLSIIQEMAEHSPLPISAIPTAGLPHLIG
GRVAYDATPEYFARYGRQMVEAGARIVGGCCGTTPAHIRALAQAVRGVEPGSRRVAVSVR
TRSDETKATRQAQASRLAEKLGRKFVVTVELDVPRGLDMSSLIQAAEALRDQGCDCINIS
DGARARLRMNPMVVGRLVQEIVGIEVIQHFACRDRNLLAIQADLLGAHALGLRNILAVTG
DPTQVGDYPTATSVFDVDAVGLVRILRAFNNGVDLSGTPIGEKTAFLIAVAYNPLARNPE
EEIDRLRRKADEGAHFIFTQPIYEMSVLEIAIREAERVGLPLMLGVLPLRSSRHAEFFHN
EVPGIQIPEEMRRVLAELEGDDAKRYGIEQAQQFLRQAKGMTSGVYIMPPALSPHVAGQV
MEALH
>A0A831TYU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MRIIDCFRRGRPVFSFEFFPPKSEEAVRELYRTIAELRELGPDYVSVTYGAGGSTRTLTV
DLVTRIKREIGIEAMAHLTCVGHHRDEIAAILDQLAAAGIENVLPLRGDPPRGEAHFVRP
EGGFGYASELVAFIREHWDFCLAGACYPEGHQECPDPETDLRNLKRKVDAGVDFLITQLF
FEPHLYFDFVRRARAIGIDRPIVPGIW
>A0A849ZEK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polyangiaceae bacterium|TrEMBL
MVSSDHPPASGKDLQLPFLEAVERSLLVSDGAMGSLLYERGIFVSQNFEQLNVARPDVVK
RIHADYLEAGAQIIQTNTFGANRFRLERHGLVGEVRRFNLEGAKIAREVVGKRAYVAGSI
GPTGLVPGADRARELNEAKATFADQAAALAEGGCDLLVLETFRHLDEICIAIEAARVAAP
GVPIVAAVTFDSEGTVADGTAPEEVAKILASFGPDVIGVNCGDGPQLSLTMAERMRGAAL
PIAVQPNAGLPRNVDGRLLYMATPEYFDVFARRMIQAGARIVGGCCGTTPDHIKWMARSV
RMLAGLHGEEATRTAAVEVRGPNVQAVEPTPLAERSDFAAKLAAGKFVVSVEVNPEPGVS
PESALTASKMLIDAGVDIVNVADGPRATARMSNLAFCALLVARHNIQPIVHVCGRDRNML
GQMAHFLGAHALGLRNLVIITGDPPKVGDYPEATAVYDLDSVGLLHMASQMNRGLDPAGK
PLRGGKTSFLCATGFEPGAQDLDKEIERLEAKVAAGADLVMTQPVFYRDLLEKVLRRIEH
LKVPVMVGVLPLVSYKNAEFLHNEVPGMQIPEEIRERMRRSPPGAEARQEGVRIAREMLF
SVRERVQGAYLMPPLGKYELALEVLDGLSR
>A0A2D8JCE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKITDHIERFKGETQFTFEILPPLKGQNISALMEVIEVLMDFKPPFIDVTYHREEHVFKK
LENGLHEKKIIRKRPGTVGICAAIQNKFNIDAVPHILCGGFNKEDTENFLIDLDFLGIDN
LVALRGDAVKSETYFKPSKDGHQHASDLVKQISNLNKGIYLDEELLNSHPTNFCIGVSGY
PEKHMEAPSLESDLHFLKKKVESGADYIVTQMFFDNKKFFEFVELARKXGIEVPIIPGLK
PLSTIKQLNLIPHRFHVDLPEILIKEIIKCKDNSSVXKVGIDWCIEQSRELKKAGVPFLH
YYSMGKSDNIKXIAEQVFXXVKLLKSCSKF
>A0A2G8RS33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ganoderma sinense ZZ0214-1|TrEMBL
MRLVDRIAQHDPKKLFYTFEFFPPKTDQGFENLVVRIARMVSLNPLAVSVTWGAGGSTKD
RSLDLAGLTQLEHGIDTTLHLTCTNMVQGTVDAALREAKDRGIENILALRGDPPRGSEHW
IPTDSRFQHGVDLVRYIKSTPEFAHFCVGVAAYPDGHPDRETDEDGELNHLKAKVDAGAE
FIITQLFYDVDGFLQWIKKVRAKGITVPIIPGIMPIQTYATFLRMTKLCATRVPPKMMSE
LVPIRHDDSKVKDYGVKLAVDMIRQLQAADVHGVHFCTLNLEKSVTRVLETIGVAGDVSH
TANMLIADKAELPERTLTPHAAADRATKELAASVPEPDASKGEVNSAADWDDFPNGRFGD
FKSPAYGETDRWGSSALQSKATTAVSHWGNPKTVDELTALFLRYLHSKITTTPFSSTPLS
PESLMIFPHLERLTSKSWWTVGSQPAINGALSTDEVVGWGPRGGYVYQKCFVEFFVEQKD
VERIAKKVETDGAGWISYFAGNAKGELLTNVPDGGRNAVTWGVFPGQEIAQTTIIERESF
LSWKAEAFSIWDEWASFYAPQSQERSLLEGVRDKRWLVSLVHHDFLDPNALWTFVFKGER
PLL
>A0A358A079|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
VLPGIMPVTNAAQVVRFAELAGAAFPPHLAARFDAIADDPDAVRALGVELASELCQGLLD
EGAPGLHFYTLNRSTATREIAANLGLGDASSTGA
>D8KA86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosococcus watsoni (strain C-113)|TrEMBL
MQHQQNSPLIFSCEFFPPKDKESASKLRRVRQKLARIHPHYYSVTFGAGGSTRDRTFETI
SDIQADAKETGIEAAPHLSCVGSSRTSIREVLQAYQHQGVKRLVTLRGDLPSGMVDPGDF
HYASQLIEFIRAETGDHFHIEVAAYPEVHPQAHSAQADLINFKRKVEAGADGAITQYFYN
VDAYLRFMERCKNVGIDLPIVPGIMPINNYVQLARFSDVCGAEIPRWLRKRLEDFPDPAT
MSAFAIDVVSDLCYRLLEAGAPGLHFYTLNRADPTLAIWDNLGLETQPANLSAVTKI
>C8ND13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cardiobacterium hominis (strain ATCC 15826 / DSM 8339 / NCTC 10426 / 6573)|TrEMBL
MCKVPLSCEFFPTATPEGAEKLAAVRRELAYLQCEYYSVTYGAGGSTRDRTMNLVARLVA
ENGPPVMPHLTCVASSEADIRSLLDDYRALGIYRLMALRGDMPSGALENAGFTTAQQLVA
YVRELWGNNARIFVAAYPEVHPRAHTPAADLQAFRDKVAAGATDAVTQYFYNVEAFLRFR
DEALALGIDVPIVPGIMPISNFNQLSRFSDACGAEIPRWLRKRLEALQDDLPALCDYGAD
VVAGICERLIAEGVPALHFYSMNRADLIGELCKRLGWC
>A0A286FVW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ag109_G2-15|TrEMBL
MALGTASTRTDRARTVRDILATGKKTYSFEFYAPKTPQGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRATTVKETQQIVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPSGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSAEWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVEAAGCDTPVIPEVLPVTSVKMLERLPKLSNAHF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A2G2M0V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robiginitomaculum sp|TrEMBL
MSLAISSLGDARDIEVSFEFFPPKTEQAEANLKKAVRKLAPLAPDFVSVTYGAGGTTRER
THRTVVSMAKTTGLKVAAHLTCVGASKADVDTVARAYHEAGITAIVALRGDPPDGAGAQY
EPHPGGYAYASDLIAGLKRIADFDISAAGYPEMHPESPDWAAEIENLKRKVDAGASRIIT
QFCFNPDTLIAYIERVRAAGINLPIIPGIMLQPNFTGLKRMAALCKTQVPDGMHAMFEGL
EDDEPTRRLLAASIAANYCTRLQQEGLRTFHFYTLNRADLAYATCRVLGLRPRKAGEPS
>A0A2E0F410|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVIDHIKNSKGETQFTFEILPPVKGYHINSIFDNVDPLMEFNPPFIDVTYHREEYMFNE
KENGLLEKKIVRKRPGTVGICAALQNKYNVDAVPHILCGGFSREVTENFLIDLDFLGIDN
VVALRGDAIKSETYFTPHNDGHKYASELVNQITNLNKGVYLEDLEVATKTNFCIGVAGYP
EKHMEAPSMKSDLHFLKEKIKLGADYIITQMFFDNKKYFEFVDLCKKKGINVPIIPGLKP
ISTLKQLNLIPHRFHCDLPEPLIKEIIKCKDNSQVRQVGIEWCIEQSKELKSKNVPFLHY
YSMGRSSNIKKVAEAIF
>A0A3A1XSM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium WP022|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VYYIRSKRPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGVNVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNADCLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A3D4ZWD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MRAERGFDSVSMREAIDSGKFIITTEVGPPKGHHLEEMVEEAEACRGMVDGVNVTDIQSA
VMRASSLVGCLKIQQVGMHPIMQMVCRDRNRLALQSELLSAATMGITDVLCLTGDYTTLG
DHPDAKPVFDIDSVQLIQAAKGLMEGHDMAGNELDGEPPTFCLGCVVNPGAEPLEPQIMK
LRKKIDAGADFVQTQAVYDPAVLANFMEQAGDLGVPVLAGIVMLKSAGMANYMNKFVAGV
SVPKDLISRMKETESKVQTSIEITVELVNGFKDLCQGIHMMPLGWNKHVATVLKECGLA
>A7M0N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153)|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEIAKIIY
>A0A0D8BN02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia torreyi|TrEMBL
MSAKPATMGEFLASGRPSFSFEFFPPRTPEGERHLWTALRRIEALRPSFVSVTYGAGGST
REGTIRVTERIATDTTLTPIAHLTAVNHSVAELRQVIGNYAGAGVRNVIALRGDPPGDPQ
GTWTAHPQGLEHADELVRLVKSVGDFCVGVAAFPDKHPRSPDFDTDARYLVGKFDAGADY
AITQFFFGADDYFRLVERVRALGCDKPIIPGIMPVTNVAQIVRMAQLSGAAFPPVLAARL
QAVADDPAAVRAVGLEVATELSRRLLDGGAPGLHFITLNRSSVTREIFEAVR
>A0A351MHC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MHIRDVLAAGRVTSSFEFFPPRSAEAAETLYATIAELEPLAPSFVSVTYGAGGATRELTH
ALVERIGAETTLDAIPHLTCVGHSAGELEEIVGRYAAAGVSAVLALGGDPPRDQPDYDRG
ADAFRHAAQLVTFLREYRHPGEPRGFGVGVAGFPEGHPDTPNRLREMDYLKAKVDAGADY
IVTQMFFDNRDFYDFRDRCLLAGITVPILAGIMPVASMSGLRRMAELAAGARFPAPLLRA
LARVEDDPEAVTSVGLHWATEQCRDLLDHNVRGLHFYTLNRSNATREIYRTLGLRNAAVW
ER
>A0A7G5ZJ74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. Dwa41.01b|TrEMBL
MDTHNFSIEFFPPKTPEGADKLRATRRQLAELNPKYFSVTFGAGGSTQQGTLDTVLDIMA
DGHLAAPHLSCIGATRDSIRTILKQFQDKGIRRLVALRGDLPSGYGGAGELRYANELVEF
IRGETGDWFHIEVAAYPEMHPQARSPQDDLQNFARKIGAGANGAITQYFYNADAYFQFVD
NARKLGIDVPVVAGIMPITNYMQLSRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTNLCERLMAGGAPGLHFYSMNQAAATTAIWQRLASR
>A0A3B0VST5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
RFKTFMNQARDMGLHEKAFYLVGVGPLRSEKTAEFMRSKVPGVHIPDEIVERLRKTPKAK
KREEGKKICVEIIQQVREIEGVSGVHVMAYRQEELVAEIIEEAGLLPRPMQVGFDSGQEK
ARRRKRKSNQ
>A0A1C7EDM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus plakortidis|TrEMBL
MMLLDELKKRMLTADGAMGTLLYSYGIEYCNEELNIQRPEVIEKIHRDYIAAGADIIQTN
TYGANAHKLARYGLEEQTEAINKAAIAIANKAAKDGGQFVVGTIGGIRGIRKSDATLDEI
VAMVDQQAKHLLSGDPDGLLLETYYDFEELAATVTHLKKLTDAPLIAQLSMHEPGILQNG
MSLNEGLKRLDALGAEIVGVNCRLGPHHTIQAFEGVELPEKAFLSAYPNASLLDIEDGRI
VYESEADYFGRAALLLREEGVRLIGGCCGTTPKHIEAVKKRIGHLQPITEKKVEEKKPIV
IREAEALKDKPLHEKAKTERTIIVELDTPRHLDIEKFLEGSKALDAEGIDAITMADNSLA
SPRISNMAMGSIIKHKQDVRPLAHITCRDRNLIGLQSHIMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVVERAVQR
LEKKIEAGADYFISQPVYTKEKIIEIHEATKHLDTPIFLGVMPLTSIRSADFLHNEVPGI
KLSEEALDRMRACGEDKEKATAEGIQIAKELIDTAAELFNGIYLITPFVRYDMTVELIRH
IRQLDLKKASDRAYA
>A0A7K2P541|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5926|TrEMBL
PDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASFPAELKERILTAKDDPA
AVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPRA
>A0A7X0AQT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. A1T4|TrEMBL
MPAISFEFFPPKTDEQRAQMDRAAQLLKAHQPEYASVTFGAGGSTLSYTSETVQHLNKVH
GLSVAPHLSCVGGTRAELGALLDEYRAAGYRRIVALRGDLPSGMATPGDFRYAVELVAFI
RQHSGDHFHIEVAAYPETHPQADNALKDLQHFKAKVDAGADGAITQYFFNADAYFRFIDD
AGKLGVNVPIVPGIMPIANYSQLRRFSEMCGAEIPRWIAKRMQAHGDDAESVRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRAKATQSVLHQLV
>A0A1W1CUC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MFDTLIEKLNNGTYITLETTPGHSPIFAPIVEKIAELELDKYVDGFSTTDNPLAKLKYNA
LFAAKMLQDRFNKPVIATMGMRDRNKIALQSDLLGANEVDIRAILALTGDPATMSDQPRT
KGVFEGDSSLLLDIISAFNAGMDYAGKPLKHQPKHISAFAVVNAYAKNPKTLQKKIQKKI
KHGAIGIITQPVYDLESAKLLLELRDNANAECCPDKKKAELIFGVFPITKLRTAQFLSAH
VPGINVPDIWLEKLRMAHEKGPEEEYKVAFDLSKTLFDDLKALHPKIHLMTANQFEVARD
ILC
>A0A848WGB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Silicimonas sp|TrEMBL
MSPSISFEFFPPKSLAASFRLWDTIEALRPCDPQFVSVTYGAGGTTRKLTHEAVETIGKH
TGLNVAAHLTCVDATKAETLEIANRYADAGVKHIVALRGDPSGGAKTFTALEDGFASSIE
LIEALAKTGQFDITVGAYPDRHPEATSETADIDWLKRKVDAGATRAITQFFFKSETFLRF
RDRCVAAGIDIPILPGILPIQTWKGARAFAERCGTAVPTDLAQAFETAERDGRTDLLATA
VCTELCSNLLESDVDHLHFYTLNDPKLTREVVHALGLAPPVALEKVA
>A0A413AQ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus asini|TrEMBL
MKIRELFQENKTVMSLEVFPPKKESGLETIYDTLQALGSLAPDFVSITYGAGGSGGCNQT
LELAATIKERYGIEPLHHLTCVNNGTEDLSELLAGMKAADVKNILALRGDLPETGAPRED
FCYAKDLVAAIKRDPDFCVGAACYPEGHISQAEDQENYQHLLEKEQAGADFFISQLFFDN
DCFYRMVEEARKAGVTKPLVAGIMPILSKAQVQKMIFMCGSSLPSKLIKLIHRYGDNPQD
LQKASLEYAWQQLGDLVAHGVDGVHLYTMNRPEIALQTFDYLRGESL
>A0A1Q5C9T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TSRI0395|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVRA
TQQIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKDRILAAKDDP
AAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A4P2QCT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
MTTRSKMERLLEERRFLVSAELTPPRHHDPTRLLQHARAMAGCVDVVQINDHLLSQARCA
NMAVGHLVRQEGVEPVLQFSLRHRNKIALQGDLLGMAALGLSNLIILGGYPCSIGSDPDA
KEVSDVDSLTAIRLTSRMTREGKLFNGDGLSPAPYFHVGTIDFPCPEQAIAGAMERLAAK
IEAGARFIQVQAVFELAPMRRWMAAVVERGLHERARFVAAIFPFAGVDRLSFLQKVPGLV
VPEHLIERVRKSGDAEGESYRITLELLQGLRDVPGLAGLHMRSIGAEDWVPRLVEDAGLR
RAA
>B6APU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospirillum sp. Group II '5-way CG'|TrEMBL
MTFREALNAREFLVTAECSPPKGTRIDGLLDRLTPLKNRIHGINVTDNQTGVMRMCPMAM
GLHLKGIGLDPIIQITLRDRNRLAIQSDLLGMSSLGLSQVLCLTGDPPKLGDHPEAKPVF
DIPTQELIRAITLLNGGTDLSGKDLNGKTDILPGAACSPEGDQEAEFRKFEEKFDAGARF
FQTQAVFSAEKMEEFMRFASPFSVPVIAGIILLKSAKMARYLNDHVPGITVPAPLIERLD
KCPPGQTLESGIAIAAETIRAIRPLVHGVHIMTVGAEETIPRILDQAFG
>A0A3B0S6A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MYAVRLFCTRHARVFESVYQGLEKVFLSLHPLLKKIGYNRLERPVALVEKISKGLLFDCK
MCGQCVLSSTGMSCPMNCPKNIRNGPCGGVRDGGFCEVSPKMRCVWVEAWTGAEKMKDGL
ARIRVVQPPVNRELKGSSSWLRVVREKGVMKDASKRQLDPDKSELAQAFAKARKLEPAAV
PLAREPVAALAEQAVKEQTSVLTDDGVAD
>M0QLK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia soli NBRC 108243|TrEMBL
MTSAAHSPSIVDRLSAPHRGPVPFSVEFFPPRDDEGEMRLWRAVRVFERLGPAFVSMTYG
AGGSTRDRTVRITGELAEQTTLLPVAHLTAVNHSIDELRALVGSYADRGITNILALRGDP
PGDPLGEWHAHPEGVEYAQELVRLIDELGDFHVGVASFPEGHHRARDLDHDTETLVGKLR
AGAEYSITQMFFDVEHYLRLRDRLAAADPEQAAKPLIPGIMPITSLASVRRMVELSNSVI
PPSVDARLAAAAGPGDEEDRAAVRAVGIDLATEMAERLIAEGAPCLHFCSLNFAKATSEV
LQRLGVDVSAAVPVATPS
>A0A429DPC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. WAC 04197|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTPRTLHTSIKLSGAPAPRRLLDRLEPLA
DDPKAFRAAGIDAVTELGERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A1T0C5V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>D4VMU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides xylanisolvens SD CC 1b|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAADINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A517QSL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassoglobus polymorphus|TrEMBL
MRIKEIYAAKSFGLSFEIFPPKTEKGDQLLIDHLSRLATHSPDFISCTYGAGGTTQDRTI
ELCEMIQSKFDLPATAHFTCVGSTQEQLRDWLTKANSRGIQNIMALRGDAPAGTDSFEAV
EGGLRYANELVSLIREHHPGLGIGVAGYPEKHPEAPDAETDLVNLVRKVDAGADAIFTQL
FFNNANFFRFRDEIEKRNVSVPLVAGIMPITEFARIKRITSMCGAVIPEELAAKLEAVQD
DQEAQFEIGVEFAIQQCQELVDSGVRGIHFYVLNKSEACERILDSLQLPQTV
>A0A3B0ZDQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MNTQKKYQKSFSCEFFPPKTEKGAENLRKTLSELATLNPAYFSVTFGAGGSTQEGTFDTV
KAIQEKGYAAAPHLSCIGSTKESIRELLNGYVALGVKRIVALRGDMPSGMRETGEFRYAN
ELVEFIRRETGDHFHIEVAAYPEFHPQAPNAQVDMENFARKVKAGANAAITQYFYNTDGY
FRFVDDCEKLGVDIPIIPGIMPITNYSNLKRFSDMCGAEIPRWIAKRLDGYGDDKVSLIA
FGEEVVSEMCQKLLDNGAPGFHFYTMNQAGPTQKLWHNLGIASKQ
>A0A3Q9BPE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Undibacterium parvum|TrEMBL
MTAHNFSIEFFPPKTAEGTEKLSITRAKLAALQPKYFSVTFGAGGTTQQGTLDTVVEIRK
EGYDAAPHLSCVGGTRESIREILQQYKAHDIRRLVALRGDLPSGYGMGGEFRYANELVEF
IRAETGDWFHIEVAAYPEMHPQARSPQDDLNSFVRKMQAGANAAITQYFYNADAYFQFVE
LAQKAGVTAPIVAGIMPITNSNQLLRFSEMCGAEIPRWVRLKLASYGDDTASIKAFGLDV
VTHLCERLLAGGAPGLHFYSLNQAAATTAIWQRLV
>A0A4V6L9C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRSQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1D7Y6I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces fodineus|TrEMBL
MNPAVTVTPAVGAALLDDFSLEMTGKDVPRLEEAQGSIPRGTRINITFLAGEDLGTRLAA
ARAVKRLGFVPVPHISARRLPSRAALEEFLSGLAADGTAENVFVVGGDPARPEGPYEDAL
AVLRTGLLQHYGVRHIGISGYPEGHPAIADRALWSALTDKAGVIGAHRFGGDVITQFGFD
VDPVLTWLEAARARGVHLPVRIGVPGPAGIRRLLGYATRFGVATSASVARKYGFSLTNLM
GTTGPDRFLHTLARRYDPERHGAVKVHFYTFGGLGATSEWVADFRRGDRQG
>A0A3B1DK22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MHIRDIFKKQRTTFSFEFFPPKGPEAAEALFATIADLERLRPTFVSVTYGAGGSTRELTN
DLVVRLQDQTHLDPMPHLTCVGHDEGEIHAILERYARHGISNILALRGDHPAGEAAYDHS
RDAFARAAELVACIRRFNDSGAHPNPAGFGIGIAGFPEGHPETPNRLHEMDHLKAKVEAG
ADFIITQMFFENRDFYDFRDRCRLAGITIPILAGIMPITTIGGMRKMAELALGSRFPASL
IRAINRTGGDPEAVKRVGVHWATEQSRDLLDHEVAGIHFYTLNRSKATQSIYDTLGVRDS
TDLLGA
>A0A1W1E411|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKTSFEFFPPRTNKGQQTLTQVRQELSVVNPDYFSVTFGAGGTTQDATLETVLNIQKNDN
ISAAPHLSCIDSKKDNIITLLDQYKSAGINRIVALRGDIPSGVRDIGDFHYANELVEFIK
THYNDHFHIEVAAYPEMHPQAKNIQTDLAHFVNKVKAGADGAITQYFYNADAYFRFVDEV
QKLGINIPITPGIMPITNHAQLVRFSNMCGAEIPKWILERLKLYENDLNALSTFGTEVVT
ELCQTLKNQGVNNFHFYSMNRTQPSLDIAKMLV
>A0A354GCA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetia bacterium|TrEMBL
MHLLTMNNLKEKQLKNNNKPLLLYGITPPRKDIDENKLQEINAKRIDRIKKLPIDGLIVY
DVQDESLRNNEKRPFPYIATIDAFSYVNLYLNSLSCDKIIYKPVSNQDAGEFKKWLNSPG
ILNNNYVFVGSPSTKLKPQMSLDDAYKIIAVEKPEITFGAIMIPERHQVKNNEHERVINK
SNQGASFFISQCVYNIELTKNYLSDYYYFCINNSIAIQRQVFTFTPCGSVNTLNFMKWLG
ISIPKWLENELYNSANILEKSIEENLKNIAEIIKFCKEKNIPYGINIESVSIKKEEIDAS
IYMIETASAMLKR
>A0A8F7G5B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. D749|TrEMBL
MKITDHIKNAKGKTLFSFELLPPVKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QANGLLQKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHCYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMSTDFKYLKKKVEAGAEFIVTQMFFDNQKYFDFVKKCRENDINIPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNNEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKKIAKAIF
>A0A8C8B918|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Otus sunia|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAADL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPVIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>R9GT12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcticibacter svalbardensis MN12-7|TrEMBL
MKIVDHITNAKGKTLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDNAFIPTPNGYAFASELVQHVADMNKGKYVHDDMESAEKTDFCIGVAGY
PEKHFESPNLDTDFKYIKLKVDLGAEFIVTQMFFDNSKYKAFVDKCRANGIHVPIIPGLK
PITNSKQLISLPKTFHLDIPLDLTEAIQACNNEKEVKEVGIEWMINQCKELKEMGAPVLH
FYTMGNAEPTKKIAQAVF
>A0A1Y5CWF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bermanella sp. 47_1433_sub80_T6|TrEMBL
NPDFFSVTYGAGGSTRDNTIDIVTNINNLGIAGAPHLSCVGESRDSIKELLNHYASNDID
RIVALRGDLPSGMAASTGELKYANELVELIKQEHGDRFQLEVAAYPEMHPQAGNFEQDLI
NFKRKVDAGADSAITQYFFNIDSYLYFVDRCLDMGIDTPIYPGIMPITNYTKLARFSDAC
GTEIPRWIRKQLEAYGDDSESIQKFGEEVITMMCEDLVENGVPGLHFYTLNQADPCLKVW
NNLALW
>A0A318RII4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia limnetica|TrEMBL
MPAFDRKTLEEVTTILGECSDAVLVGEHQNRPDFPPTVMAQIIRGAGGCPWVTLTCRDRN
RVVLEQELMGLGLAGADGVFCVTGDGRAQGVRQDVTQVFDLDGTRLAALAAQADLAVGVP
EAPEAVPMGIRPARLLEKQKAGAQMAVLNHVSTVGAAAMFVDRAQRLGVTMPIIAGVAVY
TDERSARVLAAFPGLHLDDGQIERVLASPDPVEEGIETAVREAVQLLEIPGIVGVNLSGL
ASGAGEVAAARVKAEIALRLRERLTHTTGLVGRQRG
>A0A0P9WPY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. phaseolicola|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGTPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A417HWQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. AM28-25|TrEMBL
MKVSQLLNQDKATLSFEVFPPKTSSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>A0A1V0NGD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNLIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTF
>A0A7V0PNF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MESQKRHNPVYSFEFFPPKTPEGVEKLRRVRARLAVLGPRFFSVTFGAGGSTRERTFETV
AEIQRESGIEAAPHLSCIEATREGVRAILSRYRDEGIRHIVALRGDLPSGSGTGGPREFR
YAADLVAFIRAETGRHFFIEVAAYPEVHPQARGARADLLNFQRKVEAGADGAITQYFYNA
DAYLRFVDECEARGLDLPIVPGIMPITNHNRLAHFSDACGAEIPRWIRKRLEDFGDDRDS
IRAFGTEVVGDLCRRLLEAGAPGLHFYTLNQAAPRLAIWENLGLGRIDTAGSPSAHRP
>A0A845A1R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantiacibacter arachoides|TrEMBL
MTSPAFPAQSDHFATQPLFAGLPGDVTVSFEVFPSKTEKAEDSMLKAVHALATLGPSFVS
VTYGAGGSTRDRSLATATRIAREVHVPVAAHLTCVGASREQTLAMADKFWDAGITRIVAL
RGDMPNDAGKLDHPFEAHPQGYSCAAELVAGLLERHPFDVSVSAYPEMHPEAKCADEELA
YLKRKLDAGASRAITQFFFSSDAFLRFRDRAAAIGIDKPIVPGILPVHNLARTKAMAAEC
GATLPDWIVDLFEGLDDHPQARELVSATVNAEFCRRLYAEGVREFHFYTLNKSELAYATC
HLLGLRPVRENLLEQAA
>A0A7X6S830|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacteriaceae bacterium|TrEMBL
MSAVATPSQPAPIARRTRVPVSFELCPPRTDAGRASLERTIDHLAAIDPGFISVTYGAGG
TSGGRSLEVLRSIRTRTSVEPLAHLTCVGNTYAGATALIREFLDAGILSFLALRGDPPEG
SEEGDDFLGDLGSAAELVQLIHRVQAERAQYSETSVSGVPGAAVVGAPGRARIAVAAFPN
GHPRSRGVGQDIDTLLSKQAAGATLAITQLFFHADQYLAFVARAQAAGVTIPILPGIMPI
TNPARLRRVLELSGEEVPAELEIALQVEPDDEGRTRIGIEYAAELSRQVLAGGAPGIHLY
AFNEHTTVLAVLEAAGLIADLPFHSIPRVLRPASDRRTVFQTPSTRREQP
>A0A6P5PPM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mus caroli|TrEMBL
MNRQKAKVLPAGHCYPSLGMWAPEAGCVRLSVPPSISRNPAMVNEARGSGSPNPRSEGSS
SGGESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRF
DRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCQQRPEEITG
HLHRAKQLGLKNIMALRGDPVGDHWEAEEGGFSYATDLVKHIRTEFGDYFDICVAGYPRG
HPDAESFEDDLKHLKEKVSAGADFIITQLFFEASTFFSFVKACTEIGISCPVLPGIFPIQ
GYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHF
YTLNREVATMEVLKQLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQD
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLS
GEPNRHGYRVTCLPWNDEPLAAETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDSCLWQVVEDTFELLNRHPTERETQAS
>A0A4R1GHW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phorcysia thermohydrogeniphila|TrEMBL
MTFGEKLKAGKFLITAEVAPPRGTDWKSVVKGIEPLRGKVDAFNVTDCQRSMVRMSALAM
SKLLLDSGFDPILQLTCRDRNRIALQSDLLGAAAFGIKNICLMTGDFTTLGDQKDAKPVF
DVDSVGLIETAKRLTEGYLLNGKELKGVPEFCIGAVFNPFAGPFELQIMKLEKKIRAGAL
FIQTQPVYDVKVAEEVNSLISELGAVPIIGLLPIKSLRMANFMKKLNPTSIPDSLVEGLE
KANDPAKYGWDYIIDLAHAIAEFGRGIHFMLVGKTEELASFIDYLRNHERYNHKF
>A0A3S4HTG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Avibacterium volantium|TrEMBL
MSYAKEIDTLNNHLSGINGDINVSFEFFPPKNENMEKILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKHIKQETGLEAAPHLTGIDATPEELKKIAQDYWDSGIRRIVALRGDEP
AGYDKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPAWMAKMYEGL
ENDQTTRNLVAASIAMDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGVRPE
>A0A2N5WG40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVVNRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>A0A1E8EYW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium acetireducens DSM 10703|TrEMBL
MSLKNLFSSKKPVISFEIFPPNKASSINTIYKTIDNLAVLNPDYISVTYGAGGSLVDNKT
IEIASIIKNQYNIEPLAHLTCVTSTKKDINYVLEKLQENNVENILALRGDLPEDDSFEFP
NPLHFTYASDLINHIKNNKDFCIAAACYPEAHIDCKDLNTDLKNLKNKVDIGVDFLITQL
FFDNKFYYDFEKRARALDIKTPIEVGIMPVVNKKQIERIVKLCGASLPEKFIKIMNKYEN
NPEALKDAGIAYAVEQIVDLLSSGVSGIHIYTMNKPDIAKRIVDSIYSIVKAIERSN
>A0A1C4DL66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kosakonia oryzendophytica|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAVPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCAATGIDVEIVPGILPVSNFKQAKKFADMTNVRIPAWMSQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A4R5XNZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter nitrophenolicus|TrEMBL
MSPPSLIETHPNLSDAAPVALSYELFPPRSPAAAETLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIIGQLLDTGVRGILALRGDLPND
GQVTDGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPARHPESPSEEHDVEVLLA
KQRSGADFAITQVFFHADQYADLLTRARRAGVTIPIIPGVMPLTSLRRLNRLGELTGVEP
APELMARLAAADSDLERLHIGVDATVDLSNAALDAGAPGIHIYTFNEHQSALEVLDKLAL
PRRGRAGVRPASTVRPQLAS
>H7FMV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium frigoris (strain PS1)|TrEMBL
MKVTEHIQDAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMDFNPPFIDVTTSREEFIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGINN
VMALRGDAMKDEQSFVPKVGGNNFAVDLVQQINLLNEGKYLHDVMHIDNKADFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNSKYFEFVAKAREMGITVPIIPGIK
PLAVQRHLQILPQIFRIDLPEDLIDAVDKCKTNADVKEVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIKQIASKVF
>A0A2A2Q2F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiae bacterium Tous-C2TDCM|TrEMBL
MHIQDILAKGGPTLSFEFFPPKTVEASEALYETISELEAYDPSFVSVTYGAGGSTRELTH
DLVVRLKTTTSLDPIPHLTCVCHEESDISSILGRYAEEGVGNILALGGDPPRDLKNYVKA
NDAFQQAADLVRYIKRFSETGTHPDQRGFGIGVAGFPEGHPATPNRLKEMDFLKAKVDAG
ADYIVTQLFFHNDDFHDFRDRCALAGINVPIIAGIMPVTSTKGMERMADLAAGARFPAKL
IRALNRAGDDAAAVEKVGIHYATEQCSDLLVHDVAGIHFYTLNKSHATREIYASLGLRVA
RPTGA
>A0A370KPB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium grahamii|TrEMBL
MALNSDARRKIGISFEFFPPKSEEMEGQLWNAVNELQDWNPDFVSVTYGAGGTTKAPTLA
TVSRFLAETPLATASHLTCVGATKDETHSVIDSFRKVGVKHFVALRGDAPGGVGAPYQPH
PGGYANAAALVAGLREIGDFEISVSAYPEKHPESRDTAADIDMLKQKADNGATRALTQFF
FDNDNFERYLEKVRAAGVSIPIVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFDDK
PEERAKVAAEVAAEQIEDLARRGLTDFHLYTMNRSPLVSAVLTNLGFTREGARKAGAAA
>R2RE26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus raffinosus ATCC 49464|TrEMBL
MSSALSFEVFPPNTQIGTEKLFKTLKELQQLEPDFISVTCSNNRQTIEETTLKVADYIHR
KLKVPTIAHLPAAYLSQSQLAELVKRLDQIGINQILALRGDILPDLPPKKDFVYASDLIQ
YVKREAPHLHISGACYPESHPESLNRIEDIKQLKHKVAVGCEQLITQLFFDNDLFYQFQE
SCYLADIKVPILAGIMPIVNRNQALRLIKTTNTKLPRKFLAILEKYEHDPVALREAGLAY
AIDQIVDLTTQDVSGIHLYTMNNAEVAKHIYHNTKNVLNGQWKAG
>A0A8H6NSB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum plurivorum|TrEMBL
MDKITDKIAALPADANYFSLEFFPPKTTMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
SQKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALEDAKALGIRNILALRGDPPRKDE
YRDAEDSDVDDVDDFVYAIDLVKYIRKKYDDYFCIGVAAYPEGHADESHPLGQSFEHDLP
YLVEKVQAGADFIMTQLFFDIKAYDNFERILREHPSGAFKTIPLLPGLMPIQSYQMIKRT
TKLSHAKIPDNVMARLEAVKGDDEKVKRVGVDILSELIEQVREVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDHEEEDEVAVVDDVPGAPVPTFQLNGVSPVPAGTPRALSGRRQS
SIGSDPHNRVIVSSASNPAYETTAASLTAEPVNTRANTLAISEGEGVLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVTQAVGLWGTPKTVQDINQLFVRHIKGQLSAIPWSEE
ELLPESNIIQQELLELNSRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKSFVEFFLP
SADWAGLVARLNEVKDGSICFYAANASGDFVSSDASGGLVLEGAESSTNAVTWGVFPGKE
IITPTIIEEVSFRAWAEEAFNIWGEWAKVYGKGSESEALLERVRSEYWLVNIIHHDFVDR
DALWKLLRGEKEN
>A0A084AAZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris GE214|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYLDKTQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGADKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>A0A1J8QJE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopogon vesiculosus|TrEMBL
EAKQHGCRNVLALRGDPPQGKDEWEAVEGGFVHGIDLVKHIHNEYGDYFDIAVAGFPQYQ
LLPPEERELEMKYLKEKIDAGVDFIFTQMFYDVEVFIAWVKAVRAAGITIPIVPGIAPIQ
TWNGFMKATSLANTKIPQYFLDALEPHKNNDEKVREIGTKLVAEMCRKILAADLGIKGLH
FYTMNLEKGTTMLLEELNLMPRVETIKPLPWRQSLTPNRRQENIRPIFWANRAESYLSRT
ENWDEFPNGRFGDSRSPAYGELDGYGIWLKQTAKALKLWGEPKSFEEVASLFSRFCSGGL
KALPWSDQPASSETSAIASQLAKVNELGFLTINSQPAINGVRSDDPQFGWGPSNGYLYQK
AYMEFFVGPQLLELLLAHIDRDSNMTYYVINKQGDLRTNTHSEGPNAVTWGVFPGKEIIQ
PTVVEALSFMAWKDEAYELGVKWANIYEAGSPSRQLMMEIMGSSYLVNVVHNDFKDPEAI
FEPFFKAGAEYQSQHLNGSAAPNGLAN
>A0A1F9PDH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium RIFOXYA12_FULL_46_15|TrEMBL
MSELYTQSRLEKVLKAGHLGVTSECGPPRGSDAEEVKKKGLLIKDYVDAVNVTDNQTAMT
RMSSLAACIHLKLLGIEPVLQMVTRDRNRVALQSDILGAASFDIPNMLCLSGDHQSFGDC
KSGQNVHDLDSMQLVQTVRYMRDEGKFLGGDAIKRPPRIFVGAAANPFADPFEIRVPRLA
KKIACGAEFIQTQCIYNIDKFKEWMRQAVERGLHEKAFIMAGMTPMKSVGMAKYMKNRVP
GMDVPDEIIARLAGVPKDKQAEEGINICVEHILELKEVKGVAGFHIMAIEWEEKVPEIIK
RAGLYPRPQV
>A0A511MHF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia ninae NBRC 108245|TrEMBL
MTFDNARGRSTPGRPPRTHPNVSGTPSVVQSLRAHSGAAVPFSVEFNPPRDAAAEARLWR
AVRQFERMHPAFVSMTYGAGGSTRDRTVRVTGELAQETTLLPVAHLTAVEHSLGELRSLV
GSYADSGIRNILVLRGDPPGDPLGEWQQHPEGVAYAEELVRIVRDLGDFHVGVASFPQGH
HRSPDLDSDTAFLAAKLRAGAEYSITQMFFDVEHYLRLRDRIAKFDPIEGAKPIIPELMP
ITSLRTVARAEELCGRALPAAVLDRLNKAAGDAPDDNQAAVREVGIEIATEMAQRLIDEG
APCLHFITLNFAKATTEVLTNLGYGVTAAPISA
>A0A511MXC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus cellulosilyticus NBRC 106333 = KACC 11606|TrEMBL
MWMSIELVPRSPEHLQEELAFIRDEFPTVNAVNIPDLMRMPIRSWDACTQVRGELPRVSP
IPHFRAIDLDLRKPLPFAEKLRVSGVKEVIVVTGDPPTDMSRKVYPTSCIDAIRKFKREL
PEVKVYAALDPYRSSLRGELEYLERKQEAGAEGFFTQPYFDLRLMEVFAEMFEASECRDL
PIVWGITSVVGERSRNYWETRNRAIFPREFQPTLEWNREFARQAIDWARVHGGHLYFMPI
RVRVKDYLQGVLPSGV
>A0A0T1Q2M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Root431|TrEMBL
MSPTYSFEFFPPKTDKGERTLWDAIRRVEALSPDFVSVTYGAGGSSRDRTIDVTKRIATE
TTLRPVAHLTAVGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRGAWTPHPQGFAYAY
ELVELVRSLGEFRIGVAAFPEGHPRSPDPASDLAHFVAKCRAGADYAITQMFFDPEDYLR
LRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAKDDPAAAYRIG
VEHATQMGLRLLDEGAPGLHYITLNKSTAALEIHRTIMSARSVVHV
>A0A1F9P8D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium RIFOXYA12_FULL_46_15|TrEMBL
MNLKESLEKKRFVVTSEVQVPLGDEEPEAVAESLNKVKGRVDGLSVAEIEFEGVVSDTIK
TCGILKQNNLNAIYQTTTRDKNRYQLQKDLTLAHETGVENLLVFTEDYRIAGDTLQESMF
FHVDSGKLASVMDHLRQGVTIEGKQLDGKIDFVLGSGVETPWGKNMPKRGMEEMEDMMNV
GAGYFLTTPIFDVDQFARFMKQVEPFKVPVIAEVMILRTAGMGKFLNRHFKSGLVPEWVI
QKLMSAPNKAKASMELFADTVNSLKDICQGVHIITIGGVDNLVQYLNAAKLR
>A0A318I2Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenibacter sp. ARW7G5Y1|TrEMBL
MKVTEHIKKADGKTLFSFEIIPPVKGRSIQELYNNIDPLMEFKPPFIDVTTSREEYVYID
RNGLLDKRLTRMRPGTVGICASIQHKYGVDTVPHVLCGGFTKEETEYVLVDCQYLGIQNV
MALRGDARKEEQYFNPTQGGHAYASELVKQIHALNHGNYLHDKVETVHSADFCIGVAGYP
EKHLEAPSLTTDLRRLQEKVEAGADYVVTQMFFDNQKFFEFVEAAKKMGINVPIIPGIKP
IAVKRHLQLLPQVFKIDLPQDLIDAVDDCSNNADVRQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIEAIAKELF
>S5XT76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus aminophilus JCM 7686|TrEMBL
MTQIPDFRARPYSIELTPAVLAKTPDLSASLPPGTRVYLAHLGGGPIAEMVAAARRIAEA
GFPVMPHFPAREIADARTLADWIARYQGEADVREALLIAGGRAAPVGDYHSSLQLLESGA
FQKAGFRRLHIAGHPEGNTDIDPKGGFAQTDAALRLKSAFAGGGTEMAIVTQFVFEAVPV
MDWVRRLRGQGIDLPIHLGVPGPAKLQSLLRFALSCGIGPSVRVLRRRARDLTRLLLPYE
ANELIEDLSQLDLGAAQGIAQLHLFPFGGVKPAADWAARVLR
>A0A838G9E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MTDRPSADSPEAKRRRALAALLDRPRYEVLPVPGTAEQVGAHVPTTVPVTVTVSPRRGLE
PTLELTEELVRGGYSAVPHLAARLVYDETHLAEILVRLETTGVREAFVVAGDGKRPVGGF
SDSFQLLTAVARLQRSGLGRKLRSMGVSGYPEGHPLVTADELDRALGAKQHLSSYVVTQM
CFDPGAVLGWIGHARELGVRLPVHVG
>A0A0C4US03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria heterophylla|TrEMBL
AYGIHLGTEMCKKILAHGIKTVHLYTLNLEKSALAILANLGLIDMTKIKRPLPWRPPANV
>A0A382I8L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
RDYVDAILITDNQSGRIHMSTLAAGALLIAAGVDPIVQLSCRNRNRISLLSDLLGCSALG
ITSISLVRGDRVPDDFQPRPKAIMDVNATELIRIANIMRKDENIASEGNFFLGGVVTAHA
PKPGWPAKNITEKVDAGAQFVFTHSCLDMDLLRTYMQRLGETKLLWRCHVVAGIVLLSSA
EDAQWVIKNRPNVIIPNDIITRLSNAKDPEKEGIQICVEQLQELSKMPAIAGAHIIASEK
LTNIPMAIRKSGLNKKNAN
>A0A8G0MIW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus velezensis|TrEMBL
MGLLQDLKERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIADLGADITGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTDKEVKIRREEEVI
SVRNERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKQRQKTEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A381UQH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MQKLNDLQDNVMQKMTWSMEILPQNVTDIRFIPDFVQEVYITMIPGKGFSDIILAAQKIQ
ASGKQPVPHLTARTFPGVEELRASLSGLQAAGIERVLLIGGGVPKPAGIFSSVMDMLKTE
LFAEYGIKSFDFAGHPEGNPDDPDSDYHLLEKLRWTEKRKIPTRIVTQWSLDAEKTNNWI
DSLRKNGVQNPIHLGIPGPSTLNTLLRFAKVCGVKASTQVLRKQGFNISKLMLVNKPDKI
VSELRGYDQLHLYPFGGVAKSSEWLIEWQKKF
>A0A1Y4LD48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus pullicaecorum|TrEMBL
MELREYLKHKTLLFDGAMGTYFRSVHPEYPGKCELANCNAPAKVAEVHKNYLESGARAIK
TNTFAANTHALECKFDEVRTVIRQGWKIATKVAEPYRAFVFADIGPITDPNGEYEQIVDE
FLALGAKNFLFETWSDDDDLYALAAYIKARCPDAFLIASFAVSPDGFTRQGLSARAVLER
VTNCPVIDAAGFNCVSGPNHLLAQARANADLFGKERPAADPAMLSVMPNAGYPTIVDGRT
FFENRAGYFASRMVEIVAAGAKIIGGCCGTTPEHIRLTAEALNEEEIKPEPAAAQVEVKP
RKVKNRLADKFAAKKRVIAVELDPPADDNLEKFMAGAKALKEAGVDAVTIADCPIARARA
DSSLLAAKLRRELDIDPIPHMTCRDRNINATKALLLGLSAEEVRNVLVVTGDPIPSAERD
EVKGVFSFNSAVLAGYIRELGEQGVTAPFRVFGALNVNAANFEVELRKAKRKVEQGVAGF
LTQPVFTSRAFENLIHAHEELDADILGGVIPIVSHRNALYMNNEVAGIEISQGVINRYEG
LDREAAEDLAVDLSVQLAQRMEPYTAGWYFITPFQRVSLITRILRELNKSTETDHS
>A0A381X7X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKIIDVLKQDKPAFSFEFFPPKDNDGFDKLFETIDNLKPLNPAFVSVTYGAGGSTRSKTI
DLVGRIKKEIGLESMAHLTCVGHNSDEILNVLESIKKQNVDNVLALRGDPPAGEINFTKP
NNGFGYAVELVQFICERFSFCIGVAGYPEGHPESSNREEDLFHLKKKVLAGASFIVTQLF
FDNKYYFDFVASLRKIGVDVPVIPGIMPIVNLKQIKRFTKMCGATIPHDLMVRLEEVQDD
PESVCQIGIDHAANQCRKLLMQGAPGIHFYTLNRSRATLSVLERLV
>A0A382ILH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKIKDILAKTRPVSFEFFPPRSADGIAAVLQTLDELKPYCPNFVSVTYGAGGSTRAFTEE
ITIQAKRTATVEVMAHLTCVGQTVEEINSVLDRLESEGVENIIALRGDPPRGETE
>A0A840UHX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectinatus brassicae|TrEMBL
MAISVELIPRDKEILANELQQIKDNTFPIDLINIPELLRFETHSWEGAKLAQEHGFKAMP
HIRALDINLNDKLPMQEYLHSHKINDVLVITGDPPQSMAHKVYPTISTDIIRKFHDEMPE
INVYAGIDQYRSSMRQELYHIRRKIQAGACGFFTQPFFDLRYMEMYAEMLEGSNIYWGIS
PVLSERSVSYWETKNNVVFPKDFEPTLEWNIEFARKVRDFVTKHNSNMYIMPIRADLVEY
MQGIFA
>A0A8I3AGK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boletus reticuloceps|TrEMBL
MKISKKIEQSTKEGKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWRVSFPSV
WNAGGRTSELTSEMVKTCQGLLGIETCMHLTCTNMPQEKVDIALQEARQHGCRNVLALRG
DPPAGKDEWEAVEGGFIHGIDLVRHIHKGHGDYFDIAVAGFPQNMLLPPEERDLEIEYLK
EKVDGGVDFIFTQMFYDVNIFFDWVKAVRAAGITVPIVPGIAPIQTWNGFLKATTLAKIK
IPQLYMDTLEPHKNNDEKVREIGTRLVADMCRKILDAGLGIKGLHFYTMNLEKGTKMLLE
ELNLVPRIETIKPLPWRQSLTPSRRQENIRPIFWANRTKSYLSRTEDWDEFPNGRFGDSR
SPAYGELDGYGVSLKQTKEEALKLWGEPKSFSDIAEIFARFCEKQLRALPWSDQPASSET
VVISSHLAKMNRLGFLTINSQPAVNGARSDDPRFGWGPSNGYVYQKAYLEFFVNGDLLDL
LVAQIELDPNMTYYVINKQGDLRTNTHSDGPNAVTWGVFPNKEIIQPTIVEAISFMAWKD
EAFELGCKWAYVYDAGSLSRKLIMMMNDFYLVNVVHNDFKDPNAIFVPFYKVGEEYATSH
PQQNHVAKTNGFVN
>A0A7V9PRZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MRAALLRARYELLPTASVEAAVVAALPTDVRLTITASPAKGLDATLDCAERLVGHGYQVT
PHLAARMVRDRAHLAELAQRLVALGVTDVFVPAGDAEPAAGDYHGSLDLLRDLTELGRPF
PEVGITGYPESHPTITDDVTVQAMWDKREHATYVVSNLCFDPAMIRRWVTRMRGRGVTLP
VLVGMPGPVERAKLLTMATRIGVGESTRFLAKNVSIFTRIAAPGGWRPARLLDQLAPMLT
DPAAAVVGLHLYTFNQVAETERWRHELLGTSVPAAR
>A0A382XJN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
TKEEISEILTEYSKKDLNRLVVLRGDLPSGMASSGDFPYAVDLIKFIKETQNDKFHIEVA
AYPETHPEAPNPEADFKNFVNKVSVGADGAITQFFFEPEPFFNFVENCEKKNISIPVVPG
VMPIHNAEALLRMAKNCGTKIPLWLKDGLKRHSNEEDLVKYGIDIVTNLCEKLLNFGVPG
IHFYTINRDEPTNSIIKNLNLKFDA
>A0A381PF10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
VVVYEILSPREKDGTLNSYAENISSLLAQTHIDAINIPEVRDESGRGERPVKNQLRAEPR
EFGKLLQDIVGIESIVNRVVVHQTLEKEMVWFEETYNKYEIENLITVGGESRNITYPGPS
VNEALEAIKQNLTLDVLCGGISIPSREKESRKLIEKSKNGSEFFTTQVLYDSSKIIKMIS
HYQKRCDEQNTFPRRLLLSFAPVSSKKNIKFLKWLGVDIPTDTEKYLNENDQIMTERSME
IAINVLNETLTFLNENKIVVPIGLNVEHIMSYNFQASIEMLQELARIYREFCIKTDIY
>A0A6H3B522|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus velezensis|TrEMBL
MGLLQDLEERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIADLGADITGINCRLGPYHMIEALTEVPIFHDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTDKEVKIRREEEVI
SVRNERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A3M0ZDQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MFIADLFASERPVFSFEFFPPKTPEGRQALKRTVRLLSDLQPGFVSVTYGAGGSTREQTI
ELVAAIKQETGIETMAHLT
>A0A158J4G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia humi|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRASRAQLAKLSPKFVSVTFGAGGSTQQGTLDTVLEMQK
EGFEAAPHLSCIGSSKDSLRAILGAYREHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFNIEVAAYPEYHPQARSPKSDLDNFVRKVQAGANSAITQYFYNGDAYFRFVD
EARKQGVDVPIVPGVMPITNFTQLMRFSEMCGAEVPKWIARRLESYGDDREAIRAFGLDV
VTNLCRRLVDEGAPGLHFYTLNGAAATKTICERLNLKSV
>A0A2E4IRX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MKKFSIEILPKQKSKISELNSDFFEDVYITHIPGSSLNDLIDTAKEVSVYGLNPVPHIPA
RSITDENLLNETLESLKEVGVKDILAIGGSVKDKIGKFDSTLDMFSTGVLNNIGFKSVRI
AGHPEGNPDDKNSIQSLKNKLIWLKENKFSAYIVTQFCLSPEITNDWIMETKKLIKDFGE
DGTKIIIGVAGPSKITTLIKYAKVCGVSSSANFLMKQGLDVTKLIKHSPTDLIEKLDGFD
SLHFFPFGGIKELDDWLSKQK
>A0A2F0A608|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MHIRDIINKEQPSFSFEFFPPRSDEASTELLKTIKELECLNPSYVSITYGAGGTTRERTH
DLVEKILDSTNLIPIPHITCVQHNEEEISTILKRYISKGVSNILALRGDPPEGNINYDRS
QDSFQYASDLV
>A0A1Q6USI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. 40_7|TrEMBL
MKLSQILGKDKITLSFEVFPPKTEANYEAVKKAALDVAALNPSYMSVTYGAGGSTRANTV
QIASAIQQQYGITVISHLTCVGATKEDIDHTLDSMKEAGIENVLALRGDRPKDFEGEPFT
DFHYASELVEHIKARGDFCVGGACYPEGHVDAHNKKEDITYLKKKVDAGCDYLTTQMFFD
NNIYYNFLYRVREKGITVPIIPGIMPITRASQVKTACTLAGTNMPERFRNLVDCFGDNPK
AMQQAGIAYATDQIIDLIANGIHNIHVYSMNKPEVAEGIQKNLSEIIHD
>A0A662DHT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium|TrEMBL
MKLSDLFKKGKFVITSEIGPPKGTNIQPLLEEVELLRGKVDAINVTDLQSSVMRLGSMAV
CRLLKERNFEPVFQMTCRDRNRLALQSDLISAYVLGIRNVLCLTGDYITLGDHPQAKPVF
DLDSVNLLKAAKTLMEGKDMVGNKLDGAPDFCLGAVANPGADPLEPQIMKMELKVEAGAE
FFQTQAVYDPKKFENFIKATEHLKVPIMVGIVLLKSAGMARFMNANVSGVFVPENLIKIM
ASASKQDRPKKSVEIAASLIKQLKGMCQGVHIMPLGWDRYVPDVLEKAGLI
>A0A0R1Q5P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus manihotivorans DSM 13343 = JCM 12514|TrEMBL
MKVNQLFNKHQVISFEVFPPRQKSPSIDFSRIYGTMDALSQLDPDFVSVTFGAGGSKRQA
GTLEIASLIKSEYGIEPVAHLPASQLTGAEVDELLDQFATHGIQNILALRGDIPKSGRVA
NDFVHANDLVAHICASGHDFNVIGACYPECHPEASDLNADIAHLKLKVDAGANQLISQLF
FDNQVFYDFVAKCRAAGITVPIEAGIMPVLNQHQIQRMAEMSGVSLPEKFTAMMARYEGN
PIAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVAARIVQATRSLVRA
>A0A0R3M745|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium retamae|TrEMBL
MIVSDQASARLAALLPKASVEISSRGHQIAELTDHFAGGTDVTITFLPGDNYRRNIETAA
ALRRAGYNPVPHIAVREMVSREALDDFLARARGEADVSRILLIAGDVAAARGPFKSTRDV
AASGLLEVHAIASVSVAGHPEGHPYLDLPDALNSLKAWRYWGRRTGTRVDVVTQFCFEST
PILEWIAAIDRAGIDLPVIVGLAGPATPATLTKFALRCGIGNSMRALRAQIGRFGRLLTD
TGPDDVVRGLRAAPAAATVPIAGFHLFPFGGLRKAGDWLRNYDRDLFGQQRAAMSSAGLQ
NP
>A0A255EBQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parenemella sanctibonifatiensis|TrEMBL
MITKQPPHQPTIADLLATATRPLFSFEFFPPRSPEGEETLWRAIRELESIRPDFVSVTYG
ANGSTRERTIRATERIATGTNLRTMGHLTCVSQSRADLRRTIGAYASVGLQHILAIRGDP
PGGPTAPWQAHPEGLRNATELVEMIASLGDFCIGVAAFPDVHPEQRDPDLDARLLVAKAR
AGAKFAITQFFFDPRSYVDLVARVRALDCDIPIIPGIQPVTSVKQIERFAELSGAALPAD
LVAKLHAVQDDPEQVTEVGIATAVDLCRDLLAAGAPGLHYYTQNRSLATRRIHQQLIDEL
GIDTSVPAAASEAALPVRRLGSAVARPERHEPPVVPARPGVAAVAHGAGPLERPLTLTDI
WPPYGLRVTAGDLELRPVRESDAPELLGLVAEGVHPRDRMPFLFPWTQAPAAELPANYLQ
WIARTVTETSRSRLNLQLVVRLGGRVVGVQGLEGADVDTLRTAETGSWLGQRFHGQGIGT
RMRQAVCELAFDHLGLTEVTSGAFVDNPASLSVSRKVGYADNGTERFNRADGPTLQRKLV
LTPDAFVRGEPITVEGADALRAFHGLD
>A0A6P1EZX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. VKM Ac-2760|TrEMBL
MTRARFEIIPSDGIGEDAERAFPDPAAVTLTVTSLPKHGTERTVDSAVDLARRGFRVVPH
LAARNVDGRGALDRALGRMRDAGIDEAFVISGDARSAAGSYSTSLELIRDAVELRPELAI
DVAGYPEGHPHLSDESIAKHLRERAPYLRGIVTQMCFDVNAVVRYADGLRTSGIGAELWA
GVPGPVERARLLTLGARIGVGSSLGFLARSSSVAGGLLRGRRFDPTAFVARLEAAAGERL
AGLHVYTFNELDGLRAF
>A0A818UT42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adineta steineri|TrEMBL
MYNNEIDPDAGHHPHVFKRAESDSGLQAKGCCLQTVKYVSLTEKIEKRIASNDRWYSLEF
FPPRTPSGAANLIGCFDRMAVGQPLFCDITWHPAGDPASNKETSSMMIANTMLNYCGIDT
MLHITCYGAKKEHMLEYLYKAKEFGIRSLLALRGDPPVGEKWDPKKSDFRYGVDLVKFIR
QHFGDYFVICVAGYPQGHPDSTSYEDDLGYLKEKIDCGADFIITQLFFKPETFIKFESDC
RAIGITCPIIPGIFPIQGYASLRNIVRLAKLDVPKEILACIEPIKENDEAIRNFGVQTCL
DLCSALLDTGKVHGLHFYTLNREFATIEVLKKLGLWLEEHPLRALPWKKTSNSHTRSKEN
VRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGMLTDYHLFYMKIDATRDELLDEW
GRELTCEEDVWRMFACYIGGEKNTSNKVVRHFPWTDEELSLETTLIQNNLIEFNRRGILT
INSQPAVNGKPSSDPIVGWGTSNGYVYQKAYLEFFTSADNIPALRDVLKNFPSVNYHFVN
KSGESNETNTVDEQPIAVTWGVFTGREIVQPTVVDPVSFMIWKDEAFSLWTERWGKLYEP
ESRSHAIIEQIANTYFLVNLVDNDYVEGSCLWTILDSMFEYQKVSKTNGNI
>A0A8J3LUN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planotetraspora kaengkrachanensis|TrEMBL
MALGLPSRLPERVPTVRELLAAGERSFSFEFFPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLIGRFADAGVRNILAVR
GDPRGADPLSDWIKHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSATIESDTEYFV
QKCRAGADYAITQMFFRAEDYLRLRDRVAAAGCDTPIIPGIMPVTQMSTIARSEQLSGAP
FPAKVAARFEAVADDPVAVRRLGIEHAAELCRTLLDEGAPGIHFITFNRSSATREVFQAL
SPAGAAVRH
>A0A806JCI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaesserella parasuis ZJ0906|TrEMBL
MSYAKEIDLLNQSVADLNGKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERNRTHSIVKTIQQETGIVAAPHLTGIDATPDELRAIAKDYWDSGIRHIVALRGDEP
AGYAKKPFYASDLVKLLKEVADFEISVAAYPEVHPEAKSAQSDLLYLKQKIDAGASRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMAKMYQGL
DDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGVRPE
>A0A1I6NTS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marininema halotolerans|TrEMBL
MKEKPDLRKALSQSILVGDGAMSTYLYQQGIPVGVSVEELCLSRPDWVEEVHRSYYEAGA
QVIETNTYGANRERLTRYGMEGKITRINREAVRIARNSVGEDAYVIGTIGSINAGRVPNY
DPREYRDMYEEQATALLYSDVDGITLETFLDLEELLLSLEEIRTLTSTPIFANLALIEVG
QTRDGYPLTEAFAALEKAGADGVGLNCRLGPLEIQRALERTIVPEDVWLTAYPNAGRLGQ
TDGQFQYKSTPAYFGERALSFREQGVRLIGGCCGTTPEHVHEIRNRLRGLSPLSRVNPST
VPTIQERSHEQIQVRNPPTVVDKARKGTTIIIEFDPPKDLEIADFLAGARELDKAGADAI
TLADNSMATVRMSNMALGSIMKEKTGAEPLVHITCRDRNLIGQQSHLMGLHALGMDQILV
ITGDPTRIGDLPGSSSIYDVNSFDLIRMVKQLNEGISFSGKPLKQKARFTVGAAFNPNVS
KMDAAIRRLERKVEAGADFIMTQPVYDAASIRHVAEATKGVDIPIFLGIMPLTSYRNALF
LHNELPGVKIPTHVLEEMTEQKGEEARRIGIAQAKELLDEATRYFNGIYLITPFNYWEMT
AELTRYIRQKTNSLQVAY
>A0A653NC97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea brenneri|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEATLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATREELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPEMYGCDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMNAMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVAAA
>A0A1Q4BY45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 62-47|TrEMBL
MTKARGNGSTAPKLPNISFEFFPPKTEEMERNLWDVIERLAPLTPSFVSVTYGAGGSTRE
RTHATIARILSETDLIPAAHLTCVNAPRADIDDVVARYHEVGVRHIVALRGDPTTGIGTP
YIAHPDGYQTSAELVASIKKRYPDIDVTVSAYPEKHPESRDFDADLDVLQAKVDAGATRA
ITQVFFDNDLYFRYLDRVRARGIDIPILPGIMPMHNFKQARGFVTRAGTTVPSWLEEKFD
GLDDDAETRKLVAAAVVAGQVQKLAKHGVENFHFYTMNRADLVFAISHLLGIRPSARKAA
>A0A1A2TUF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium mantenii|TrEMBL
MPAGAGCPKRMQFGPCGGVRPDGQCEMLPSPCVFDDVVPWSGQHPAPRPARAPRVLADFS
AAPFDPDDIVATAAVLAPGCDAVLVGEHQNKPDFPPTLMASLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSIDVDTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGMVAAVP
ETPTAPPVHRRPARLVEKQRAGASLAVLNHVPFPDIIADFMKTARSAGLTIPVIAAVAVF
TDSISAAVLEGLPGLELDPVVTQRVLSAPDPVAAGIAAAVSEARALLAIEGVEGVNVSGL
ASASGPRIGAEIKAEVGRRIREEATGGRDEEERRR
>A0A1X0G0N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium mantenii|TrEMBL
MPADAGCPKRMQFGPCGGVRPDGQCEMLPSPCVFDDVVPWSGQRPAPRPARAPRVLADFS
AAPFDPDDIAATAAVLAPGCDAVLVGEHQNKPDFPPTLMASLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSIDVDTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGMVAAVP
ETPTAPPVHRRPARLVEKQRAGASLAVLNHVPFPDMVADFMKTARSAGLTIPVIAAVAVF
TDSISAAVLEGLPGLELDPAVTQRVLSAPDPVAAGIAAAVSEARALLAIEGVEGVNVSGL
ASASGPRVGAEIKAEVGRRIREETMPRSGR
>A0A2M8J0P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudooceanicola lipolyticus|TrEMBL
MSAPTISFEFFPPQTLQASFRLWDTVQSLAPLGPRFVSVTYGAGGTTRDLTREAVATLHK
SSGLNVAAHLTCVSATKEETLEIARGFAEAGVKELVALRGDPPKGTGAFKQHPGGFANSV
ELISALAETGDFTIRVGAYPDVHPEAASGQADIDWLKAKLDAGADEALTQFFFEADTFLR
FRDACAKAGIDKAVTPGILPIENWKGASKFARSCGTKIPAWLSEAFEKATRDGREDLLAT
AVCTELCSTLIDEGVDRLHFYTLNRPELTRDVCHALGVTPKTTLQNVA
>A0A8G0KYU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium columnare|TrEMBL
MKVTEHIEKANGKTQFSFEILPPLKGQNIQCIFDGIDPLMEFNPPFIDVTYHREEYEFKE
LANGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGNAYATELVTQINNLNKGIYLDADLQNTNATDFCIGVAGY
PEKHMEAPSMDSDIYFMKQKIKNGADYIITQMFFDNQKFFEYVEKCRNAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNEAVKQIGIEWCIQQSKELVKAGIPVLH
YYSMGKAENIKAIAKEVF
>R0C4N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster bolteae 90A9|TrEMBL
MKIRDILAEGKPTLSFEVFPPKTEDAYDSVEKAAAEIAKLKPSFMSVTYGAGGGTSDYTV
GIASAIKEEYGVTPLAHLTCVSSTREKVHHVLGELKERGIENVLALRGDIPQDGSTPREY
HYASELIWEIKKAGDFCIGAACYPEGHVESSNKSVDIDYLKQKVEAGCDFVTTQMFFDNS
ILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTYLPSRFMSIVDRFGDNPAAM
KQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A829MKZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens BBc6R8|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYHPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNAESYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1W1YYQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Papillibacter cinnamivorans DSM 12816|TrEMBL
MDIRDAIRQGTLLFDGAMGTYYAEGKEDPPEYCELANLQDPETILSIHREYIDAGSRAVK
TNTFQANQAALGDWETAEKVIRRGYELACRASEERGVFVFADIGPVSGMEEETGAEYLRI
ADLFLSLGARQFLFETFSSGDFIRETAEHIKGKAPDAFILASFAVSPEGYTRQGISGEQL
YSNFTADPNIDAVGFNCMSGPYHLLQFIRKLKRGDKPLSVMPNASYPTVLNNRTFYGNNA
SYFSTQMAEIVRQGAEIIGGCCGTTPEYIAKTAKRLQNGIRPDRETVTAEPAEIKVEEKI
LPPNRLLEKLRKGQTVIAVELDPPMDANIGPFMEGARQLKDAGADAITIADCPIARARVD
SSMLACKLKRELGIEPLPHMTCRDRNINATKALLLGLSIEGIRNVLVVTGDPIPTASRDE
IKSVYNFNSVLLAGYITTLGKEGTFAAPFHISGALNVNAVHFDSQLDRAKRKMDSGIAMF
LTQPVLTKQALENLQQAREALPGAKILGGIIPIVSHRNALFMNSEISGIVVSDGIIRLYE
DADRERGSQLAVALSTAIAEKIRSHVDGYYLITPFKRVDIIGSIIGDIRSGAKAAVDIDA
IW
>A0A7C9JZZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agarivorans sp. B2Z047|TrEMBL
MGFHNAQQIETLNQSLSELNRDINVSFEFFPPTTETMEQTLWSSIERLQTLKPKFVSVTY
GANSGTRDRTHKVIKAIKDRTGLAAAPHLTCIDSTPDELRQIARDYWNSGIKDIVALRGD
LPEGSAKPQMYASDLVALLKEEADFDISVAAYPEIHPEAKSAQADLLALKRKMDAGANRA
ITQFFFDVESYLRFRDRCAAIGIEGEIVPGILPVSNYNTLKKFASFANVKVPKWLHNQFA
GLEHDQTTRNLVGASVAIEMVKVLSREGVKDFHFYTLNRSELSYAICHTLGVRPAEAVPA
>A0A514LBY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosopumilus sp. SW|TrEMBL
MTIRYEANPPKILPDVDTNESIKKFIERIKIISKKCDAIHLTENVLGYQRVSPLDVGKII
KNEIPDLPITVSLRVRDKSEAEIFEFAEKCIEIGFAGILILMGDPSQTGKADSGQIPSLT
VKKLREKSIDSKIDLYLSVSNNPNFSKLGKKIDAKPKGFMTQVIQNIQQVQALSENLSKF
SVIPIILFPSQKNEKSAKFLDLDLESYSKEFEELLKQTHKITGDVLLTSPNDFTGLNEFL
DKTTI
>A0A7X4L560|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. BIOML-A1|TrEMBL
MKIRDIIGQEKATLSFEVFPPKKDTDFASVEAAALGIAALRPSYMSVTYGAGGSTKGHTI
KLANEIQEKYGVPTIAHLTCVCANKDSIRTALSEMKNAGIENILALRGDIPKNYDGQVFT
DFAHASELVKLIKESGDFCVGGACYPEVHPDSANKQDDIANLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRIREAGITVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEVAAGIQANLSDILLV
>W8WUE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Castellaniella defragrans 65Phen|TrEMBL
MELQAAPSQVLEEAASGLSDYSLEVTAGGVDQAQAAVRALRPGTAFSITFLPGEDYPARL
RAAQVLRSLGFVPVPHLSARRMAGVREAESFIEALAVSAAVDRVFVVGGDPDRPLGPFRD
ALDLIETGLLERHGIREVGIGGYPEGHPAIPSDRLWAALQAKCEAIEARGMRPFIVTQFG
FEPGVIVEWLTEVRRRGIRCPVRVGVAGPAKIATLMRYAARCGVSASARAMSRYGLSLTR
MIRSAGPGGLIADLAAGLHAAGIRDVGLHYYTFGGFQQTIDWIRSFHEAQHG
>A0A3B8MJZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MRFRDYFKYPAQQIISFELYPPKTAKGMLTLKEQVIPNLVKLGPSYITVTYGAGGSTQGM
TLEIASTIRNQFDLESACHLTCVGASKADIEQIVRKISAEGIENIVALRGDTPKGQDRFT
AHEDGFGHANELVSHIRSMEGIGEGTGLAVAGYPEKHQEAPSLDEDIENLKRKVDAGADV
IITQLFYDNDTFYAYRDKVAAAGIDVPLVPGLMPIQSSHQIQRIASLCGAHLPDPLLEKL
EDAGEDDKLATEIGTEQCIEQSNALLASGAPGIHYYVLNRSSQLHRVIRGIDR
>R6VTZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. CAG:474|TrEMBL
MKVVELINIHKDKKNFSFEVLPPLKGTGTGKLFATIDKLKEFDPLYINITTHHSEYVYRK
LDNGQFERMRIRRRPGTVAIAAAIQQKYGIPVIPHVICSGATIEHIEYELLDLQFLGIEN
LLLLRGDKAKDDRVFTPVAGGHAHTTDLIEQVNRFNSGYFADGSAIKVPGTPFGYGVACY
PEKHDEAPNMEMDMGYLKMKQDMGAEYAVTQLFYDNSKYFDFVDKARAMGITIPIIPGIK
PLAKLSQLTVVPKTFHCDLPQELAAEVKRCKTDDDAKQLGIEWATHQCQELYAHGINNIH
FYTVSAVDSVAEVTRRLI
>A0A377R4I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingella potus|TrEMBL
MTAGKTLSFEFFPTRTPEGREKQTAVRALLRGFNPGFFSCTSGAGGSTREGTLQTIADIL
AEGTAAAPHLPCIGMNEEEIASLLDTYRDMGVRRIVALRGDMPSGMGASGSGLRYASELV
ELVRNRYGSLFRIEIAAYPEYHPQARSAQEDIAHFVAKARAGADAAITQYFYNADAYFRF
VDDVRALGCTIPVIPGIMPVSSFSKLVRFSDSCGAEIPRWLRLKLQSYADDTAAIEAFAL
DVVSDMCARLLEQGAPGLHFYTMNQGVLPSEICRRLGFGA
>A0A3A8N8U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus sicarius|TrEMBL
MKIRNCLNPSQPCFSFEFFPPKTDAGVASLLRTVEELAPLNPGFVSVTYGAGGSTRDRTV
ELVTHIKQHTGIEAMAHLTCVGHTRDELRDVLRRLAAARIENVLILRGDPPQGQQTFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLRHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVSALRARS
>A0A1W9LF36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium A6|TrEMBL
MKPESQSNLQSILSDGKFAVTAECGPPRGADPEIIRKKGGLLRGRVDAVNVTDNQTAIVR
MSSIAACVHLSAMGLEPVMQMVTRDRNRIALQSDILGAFSLGIRNILCLSGDHQTFGSQP
DAMNVFDIDSVNLVRMVKVMKTDGKDMSGFDLISSPRMFIGAAANPFADPFEYRVIRLAK
KIDAGADFIQTQCVYNLERFREWMRLAREEGLTEKTHILAGITPLKSEGMAKYMAKRVAG
MDVPESVIKRIGGVPKGKAAEEGFDICLETIAALREIKGVHGIHIMAIEWEEIVGRIVEA
AGLSPRPKAA
>A0A4P5WSZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetia bacterium|TrEMBL
MRLTDLFNSRRFVLSIEMFPPKTAETSEALKRSLLSLNRYNPAFVSCTYGAGGSTRGQTL
DWCQWIQQTLQRPAMAHFTCVSSTVNELSDWLHQAWQSGVRNIMSLRGDPPAGQQVFTAA
EGGLNHASELTALIRRLYPEMGIGVAGYPEKHVEAPSLDADLENLKIKVDAGADAVFTQL
FFINRSFFEFRDQCAARGITVPIVPGIMPITDFARIRRITSMCGSVIPLELATQLEAVRD
DAAAQFEIGTEHAIRQCRELQAEGVPGIHFYALNKSDACERILNALSLPLA
>A0A172UE55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas sp. DH-1|TrEMBL
MNISFEIVPRSLAAFDEQYAFVQTLSGGINIINVPDIQRFDTRSWQLATRIDRDKYRFIP
HFRAIDFKIESGELFRIIEEYGLDSVLLVTGDPPEGLKRAFYNTDVVDLIRAVRSRFPEL
NIYAGFDPHRQGLQDECDYIWRKADAGATGFFSQPFYDPRMAEIYAEHMQGLETYIGISP
ITTQASQNYWEVKNRVKFPKSFRPDYDWNVEFANNLIATAAETGLHVYFMPIRIDLAKYF
QRIRFDTAQ
>A0A075HMB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured marine thaumarchaeote KM3_70_E10|TrEMBL
MAIRYEINPPKISDTGERLERLHSRIKQISDVCDGIHLTDSVLGIERISPIIIATESKQK
IPDLRITISLRVIDKSLEQITNVTQASIEANLDGVLVLMGDPSQNSNHNSGIFPSQAVQH
LNNLEYNKKTEIFLSLPSNPNFEKISKKINSKPYGFVTQVIHNISQVQRITDHLSPKGFK
IIPCVLFPSEKNLKSAEFLKLDWSNYKDNFSDFINKIEKITGDVLLTSPNDFKGALDFLT
RLQN
>A0A7W0H4M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MRGVAEAVGDGRVLTTSLGTLPRPDATELRRRLHLIRDAFAFVKFADNPRARARVSPWAA
ATLALSEGVEPIVHVGCRDRNRLALQADLLGGRLLDIRNVLCLRGDEIEVSDQPEARAVQ
DLHVVDLISVAAEHFCVIAACDPRAGTGDAHLTRLRAKVAAGAQLLETQPVFELDRFARW
LRWLREGGIDIPLLVDVSVVATSADVELLERIPFVAAPTGLTARLRRVPSAGVEVAAELA
AGLLELDGVAGCHLDLLGGDPTPALTVAERLK
>A0A6L3V2R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus depressus|TrEMBL
MNFLEKMKNEIVIADGAMGTLLYSYGTDSCFENLNITHAEQIQQIHEAYIQAGANLIQTN
TYAANYIKLQRYGLEDHVKEMNTYAVRNARKAAKQDTFVVGTIGGIRGIKPKMIPLEEIK
RSFREQLYCLLLEGVDGILLETYYDLEELEEVLSIARKETDLPIIAQVSLHEANVLQDQT
SVPEALLHLENLGADIVGLNCRLGPYHMLRALENVPLPKHAFLSVYPNASIPAYTDGKFH
YEGDSEYFRQSARDFRNQGVRLLGGCCGTTPDHIRAFASELNGLPPVYEKTVKKRNQIKI
NTHAAANREEPPLHEIVQERPSIIVELDPPKKLITSSFFEGAKALKEAGIDAITLADNSL
ASPRVCNTALGYRVKKEVGIRPLVHITCRDRNIIGLQSHLMGLHTLGLHDVLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNDGLSISGKDLGENAAFSVGAAFNPNVRSLEKSVQ
RLEKKITFGADYFVSQPVFSEQKLVDVHEATKHLNRPIYIGLMPLISHRNAEFLHNEVPG
IKISDEIRNRMAECKDDPIRASREGLAITKSLIDTAAELFNGIYLITPFMRYDLTVELSK
YTQEASAKIARRKQHAEIITN
>A0A847FF86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MTKTSLLEALKERVLICDGAAGTMFHSRGIAPESCYESLNIVDPVHVSRLHEEYIAAGAD
IIETNTFGANAAKLEAFGREKEAGRINLSGARLAVEAAAGKGVFVAGSIGPLSRNPPEVE
LSAGRIYDIYKVQAQALAEGGVDCFILETFSSLEHIRIALSACRDTAAGIPVICQMVFLH
GLRTGFGNSISSVVSVLSAAGADVIGANCGQGPAAMLEAVKRLAQLTGKYISAQPNAGYP
QIVDGRTMYFDSAEYFASYALKLAQSGANIVGGCCGTTPEYIRLAAQRLKGVKPAPRAKS
VQESRPAEPLRERPVIDKQITVIVEVLPPKGADAEKLIDTALMLKSRGAKLLSFPENPLA
QVRMSSIAAAGLVKKQADIDTIFHYTCRDRNLIGLQSDLLGACALGLDKVLAVTGDPASL
GSNPAASSVFDLNSIKLVSLIDNMRKEMGLRISVGVAFNPNFDSISGQLERLKRKIEAGA
DFVLTQPVFDKDKAVSTARDIMKLGVPVYFGILPLLSRKSAEFLHNEVPGMSVPLNIRER
MEISDKERAIEEGKKILLELTEVLKGKVSGFYLISPAGKYGISAEIVECIK
>A0A8G2CNV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiphilium rubrum|TrEMBL
MSHEPPRAALQRWLSGPRIAPLPGSIQAVPEISFEFFPPKTEALEAQLWACIRRLEPLAP
QFVSVTYGAGGSTQERTHATVLRLVRETSLIPAAHLTCVGATRGAVDDVARRYWDAGVCH
IVALRGDVPGGAPYQAHPDGYAFASDLVAGLKRVADFDISVAAYPETHPQAASPAADLDN
LKRKLDAGANRAITQVFFDTSHYLDFLDRALAAGITAPIIPGIMPVSNFAQAKRIGEMGG
TSVPAWMAEMFDGLDDDAETRKMVAAAVAAEQVRILQANGIDEFHFYTLNRADLTYAIAR
ILGVKGK
>A0A1S3GGF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dipodomys ordii|TrEMBL
MDHRKARVLSAGHCCPSLRKWASQAGSVGLSVPPCISRSSAMVNEVGRSDGPNPRSEGSS
SSGSESSRNSSRCSTPGLDPDRYEKLRDKMKRRMDSGDKWFSLEFFPPRTAQGAVNLVSR
FDRMATGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRQEEIT
RHLHKAKQLGLKNILALRGDPIGDRWEAEEGGFNCAADLVRHIRSEFGDYFDICVAGYPT
GHPEAASFEDDLKHLKEKVSAGADFIITQLFFEADTFFRFIKACTDMGITCPILPGIFPI
QVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVF
QKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGRE
IIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSRAIIQHIHDNYFLVNLVDNEFPL
DNCLWQVVEDTFELLTRPPKRDGDVEAP
>A0A542DAC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella jejuensis|TrEMBL
MANGLPSTLPGGAPTIRELLAAGERSFSFEFFPPKTPEAEEVLWRSIREIEQLHPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWVAHPEGLNHAIELVELIRSLGDFCVGVAAFPDKHPEAASLEADAQVLAA
KAQAGADYAITQMFFGADDYFRLVDRAAALGCDIPVLPGIMPVTNIKQIQRMAELTGMAL
PAEVTDRLLAVEDEPAAVREVGIEIATELCERLLTGGAPGIHFITLNRSTATRQVFRNLQ
AANVS
>A0A1I0W716|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas ruminantium|TrEMBL
MKRVSVELIPRDEETLRGELQLLKQYEGKIDVINIPDLLRFDTRSWEGSAIAQEYFAMSM
PHIRAMDIDLDKELPMKDYLREKGIKEVLVVQGDPPQRMTHEVFPTESTDVIRKFREEMP
EVKVYAGIDQYRSSMRHELYRTRRKVQAGAAGFFTQPFFDMRLLEIYMDMLDGLDVYWGV
SPVVTAASQSYWERKNNVIFPKSFNPTLEWSVDFSRQVMEMADKKDANVYLMPIKTNLEE
YLAGVFA
>A0A536TU36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MDLATKEQSSSSAISELQRHLQDGSFVVTAELSPPVSTDPAEFIDHALALRGLVTAINVT
DGAGSRAHMSSLAAAHFLVRSGVEPVLQITCRDRNRIALQAELLGAAALGIRNILAVRGD
DPKLGDQPDTKPVFDLNTTALLATAQQMRSEHRLPSGTEIKGAVKFVLGAAELPVDPPAG
WRPNGLVSKMEAGAEFIQTQFCMDPDAVRRYAARLLELGVAQKLPILIGIAPIPSARSAR
WMKEKLFGAMIPDRIVDRLERAADPKAEGRRICVELLQQLAETPGVAGAHVMAPAFHSAI
GPVIEASRVAGTKRAGARRG
>A0A1B7TG70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hanseniaspora valbyensis NRRL Y-1626|TrEMBL
MKVDEKIENYQKDNSYEIPSFSYEYFVPKTLQGSYNLYERIDKMNMDSNPLFIDVTWNAG
GVISPNIPIPKTNDIIETSQQALQLDSCMHMTCTNMTMKEIDSALKKAYESGCENILALR
GDPPRSVEQNGKENVDASVDKYPFKYAKDLVRYIKEKYGDHFCIGVAAYPEGHPEEANSD
VLIKYLKEKVDLGATFIITQMFYNTDIFIAWCEKVRAAGIPENVHIIPGIMPITSYDSFL
RRCNWCQINVPQDLNEVLKPVQQDDEALRNLATNYVAKMCLKLFKSGHVKHLHFYTMNLE
KGSYVILKELERLLGKRLLPLAAGLNSNANKEKEMKPIFWKSRPFSYVERKKKSKILKAR
TKSTGNEFPNGRFGDSSSPAFGNLDLSLTQLIRQAESKSLSVWGTPTSIKELGDLIIGYL
KGDLRSLPWCDTPVALEAKQLLRLLISINQGGILTVNSQPKANGVPSSDQVLGWGPSMGY
VYQKQYIEFLLPKRKLKQFFELVDQKNSSTFTFMISDADDEVFIYKGDDAVTWGCFPGRE
IVTTTIVEKNSFLMWRDELFAIIKEWKNNFDTITENAAKSVEVMTEILDDYLLVSLIDND
YVNPGDLLLFTLLQLTD
>A0A4P6U1K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces seoulensis|TrEMBL
MSGTLLDGVSLEMTGKDVPRLEEARDALDGGTRINVTYLAGEDAGMRLAAARAVRGHGFV
PVPHLSARRLPSRAELERFLAGLAEADAIENVFVVGGDPARPEGPYEDALSVIRSGLLQR
HGTRHVGICGYPEGHPAIGDDALWSALTGKAAALAEAGLGGEVITQFGFDADAVLSWLEA
LRARGVHLPVRVGVPGPAGVRRLLGYATRFGVGTGATVARKYGLSLTNLMGTAGPERLLD
DLAGGYDPARHGTVRLHFYTFGGLRTTAEWITRYRTGRS
>A0A6A8W039|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoduganella danionis|TrEMBL
MANHNFSIEFFPPKTAEGAEKLRVTRAKLSELHPKYFSVTFGAGGTTQRGTLDTVVEILA
AGEDAAPHLSCVGGTRESIRQILNEYKSHNIRRLVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQARSPQDDLLAFERKVKAGANSAITQYFYNADAYFQFVE
QTQKLGIDVPVVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VSALCERLLAGGAPGLHFYSMNQAAATTALWQRLVK
>A0A3C0A1B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MRISEKLKKQKRVFSFEFYPPKKEEDIPFLKAAVAELKGLSPDFVSITQSPSSLSGLSFA
SLSNTLALSGVLKHEFSLEVMAHLTCITLKDRETLDEAVKLMRILGLENVLALRGDRAGG
GLEKPFFSRAWELAAELNGRGIFDIAAACYPEKHPEAQSLEADIDNLKRKMDCGAAFAIT
QLFLDNISYFSFREKCLSRGVTIPLIPGIMPVTGVSQLANFAERIKVKIPAGLSAALEKL
SPGGAEPGPDARAAIREFGVSYAAAQCLELLKNGAPGIHFYTLNRSKATAAVLNLVKRGL
GII
>A0A523BQ56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MSEPKTESKLERLLNEGRFVVTGEIGPPKHAGGDGIKHHVELLKNHVDAMNLTDNQTAIV
RLSSIAAAAHVLAAGGEPVIQMTVRDRNRIALQSDLLGAYSLGVRNVLCLSGDHQSFGNH
PTAKNVYDIDSIQLVQTVKGLRDEKKFLCGEEIKEHEPRFFIGAVANPFGDPFAYRVLRL
EKKVNAGADFIQTQAIFDMDRFEKFMAMVRERGLHKRVKILAGVMPLKSVGAARYMQKSV
SGMIVPDPIIDRMKGAGDPKAEGVEICVEQIKHLQTIEGVAGVHIMAVMWEDIIPTIVEK
AGLYPRPK
>A0A536TGW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MSGLEGRAPEPGAAGKAPERSAAVEQQEVAALARAASVEMTWRDVDQLESCRASLPPGAA
VFASHLPRQTWQQTLETCVAIRDRGFEPVPHVPVRLLPDVATFEHLIADLVARAHVSRVL
LIAGDSPESIGPFSATLDALRSGVLAAHGIRRIFVAGHPEGHPRLTDADLRRAERDKLAF
AAANGLELSFLTQFFFDAAPFLAWARMLRAQGVDARLVAGLAGPARLTTLFKYAVRCGVG
PSIRALGARPEAHGGTRSGADHSRNRPRPRRAGRRRHSPVFVRRARAHVRVAACARG
>A0A536WM09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MQTGSTAGPIAAPALLGASPEDERRNIQAFLLGASLELSSRDPVEINACADLLEPGTAVY
ISMPPGQTYHGIVALATRLKRAGLRPVPHVAARRIASRDALDEYLARAAGEAGVDSALVI
AGDSDRTSGPFESSLRLLETGLFQRHGIAHVGVAGYPEGHPKIAETALATALAAKKVLAR
RASLDLQIVTQFCFESEPILVWATKMIEHELPVRIGLSGPASLPRLLRFAMLCGIGNSVR
ALKARPQAITRLLVEAGPEVVVRDIARPGGAPIAGVHFFCFGGLMRTARWLRAVREGRFE
LTPDGGFRVGAA
>A0A537C6Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MAASGSSTNPMSFPASEIDVSARAGSVAELVAAGSIEISPRELHRAAEVAALVPAGTCAY
VPSLPGLPVSRVLETVAAIRRAGLDPVPHLAARRSAGREQLREFLRRAAGEHGVHRVLLV
GGDQPRASGPYSDTLQVLEEGVLADTGIREIGIAGYPEGHPRIAPAALEEAFARKQRLAA
EQGLGVYVVTQFCFAPARVVECCAALARSAPSVSIYVGVAGPTDPAALLRYAQRCGVSAS
LRALRNLGTGIAQLVTHTDPHEQVVALARYSRSRTPSNVIGVHLYSFGGAVRTARWMRER
IAG
>A0A536W8L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTGSADRIFSFEFFPPATPEGVAKLRATREQLERLGPKFFSVTFGAGGSTRDRTLAAVLE
IQAAGQRAAPHISCIGSTRESIRATLAAYREHGIEHLVALRGDLPSGTADVGEFRYANEL
VEFIRVATGDWFHVEVAAYPEYHPQSASPREDLASFKRKIDAGADSAITQYFFNADSYYH
FVDEAVAAGIEAPIVPGIMPILSFSKLARFSDACGAEIPRWIRRKLESFGDDTASIRAFG
LDVVTDLCDDLLAHGAPGLHFYTLNQASLTTIIWQRLGLS
>A0A536V5V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTGGEDRIFSFEFFPPATPEGAAKLKATREQLAQLRPKFFSVTYGAGGSTRDRTLSAVLE
IQSSGQRAAPHISCIGSTRVSIRDTLATYRQHRIGHLVALRGDLPSGTADAGEFRFANEL
VEFIRETTGDAFHIDVACYPEYHPQAKSPAEDLASFKRKIDAGADSAITQYFFSPESYYH
FVESAAALGVDVPIVPGIMPIASFSKLARFSDACGAEIPRWIRRKLESFGDDAASIRSFG
LDVVTDLCANLLEHGAPGLHFYTLNQAGLTTTIWQRLGLS
>A0A6L4AVL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobaculia bacterium|TrEMBL
MKVTEHLERATGPLISFEIIPPLRGGNVRSLMDLVDDLARFRPPFIDITSHAAEVVFEET
PQGLQRRVKRKRPGTLGVCALIQNKWGIDAVPHVLCQGFTREETEDFLIELRYLGIDNVL
AVRGDESGYQKPLLHGKTANDFAIDLVRQVADMNRGRYLQADLLDASPTDFCVGVGGYPE
KHFEAPNLATDIRRTGEKLEAGGDYVVTQMFFDNRGYFDYVERCRAAGITAPIIPGIKIL
TSRAQLASIPRTFHVDIPADLSDAVSAAPPERVTDVGVEWAERQVRELLDRGVPSVHFYV
MQSAAAVSAVLDRLQLGGKVKG
>A0A3A0W3I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus gallinarum|TrEMBL
MSQLLKALQNNILVADGAIGTIFYSEGLDTCPEAYNLTYPEKVQRIHQSYIDAGADIIQT
NTYGANFEKLKVFGLEHKVKEIHQAAVRIAKNAATENTFILGTVGGFRGIKQEDLELTAI
QYHTEIQVETLIEEGVDGLLFETYYDLDELTNIITATKRKYNIPIIAQLTALNTNYLRDG
TEINEALKTLIASGADIVGLNCHHGPHHMKESFSHIELPEEAYLSCYPNASLLDIDNSEF
KYSDNAVYFGKVAQQLINEGVRLIGGCCGTTPEHIKFIKSSVDGLSPVTDKNVVPITKKV
KKNNNQSTIKQNLTDKVKSRPTVIVELDTPKHLDTDKFFRNIKKLDEANIDAVTLADNSL
ATVRVSNIAAASIIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILTITGDPSK
IGHLPGASNVYDVNSKGLTEIALRFNQGINTDGDALKVNTNFNIAGAFDPNVRKLDGAVR
RLERKLESGMNYFITQPVYSAEKIKEVYEATKHLDAPFFIGIMPVTSYKNALFLHNEVPG
IKLSEEILSQFEAVKDDKEKTKALSLQLSKELIDTVHQYFNGLYLITPFQSVDYTLELAS
YSKTITSNKQEAIL
>J3A4B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus sp. BC25|TrEMBL
MTTRKKDLRAYLKDHLLVGDGAMATQLHGLGVPVGVSFEELCLSNPRLVHEVHTSYYQAG
ARFLETNTYSANRDALSRYGLEHKVARINRLAVAIAREAAQDDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGVDGLILETFVDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYALTDAFSELKAAGADVIGLNCRLGPAELLRSFENTVIPEDALLSVFPNAGRLG
MTDGEYAFKSSPEYFGQSALRLREQGVRLIGGCCGTTPAHVKAIADALESLEPQARVNPT
IVAGDRPTISVQNNREREKPSIVERVKTATTIIVEFDPPRDLDADQFLHGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKSRHGIDPLLHIACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMDAAVARLEKKVEAGADYIMTQPVYDAESIRNVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSTEALERMKKVQGEAARQEGIAIAKELVDTAVRYFNGIYLITPFNYYE
MAAELIQYTRQQSSLVKLAQT
>A0A7C5IZA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiolapillus brandeum|TrEMBL
CAKRNITIPIVPGIMPITNYVNLARFSDACGAEIPRWLRKRLEAFGDDTEGLFEFGLDVV
TGLCRNLLDGGAPGLHFYTMNQSAATLAICERLGLAGSAPAA
>A0A8G0RUC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis sp. MT53|TrEMBL
MLAAPTRPVAPRTPAPRARHLRDLLHTGEPLFSFEFFPPRTPEAQEKLWLAIRQLEALGP
DFVSVTYGAGGSTRGMTVETTERISADTTLLPVAHMTLVDHSVAELRHLIGRLADAGVSN
MLAVRGDPPGDPSGPWNSHPEGLTYSEELVRLIKESGDFCVGVAAFPYKHPRSADVETDT
DHFVRKCEAGADYAITQMFFDPEDYLRLRDRVAARGCDIPIIPEVFPVVRTSFIPRSEKL
SGAPFPADLAEKFASYGDDAAAVRAFGIEYAKKMCERLLDEGAPGIHFITSNQSTATREI
YREVSGRLSR
>A0A674NTN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Takifugu rubripes|TrEMBL
APSAFAFILPLGDLCRSMAIMVNQVQSVDSSWQSSKADSSGASNSSGESSKESSRCSTPV
LDADRSDRLRDKMRRRIESGDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWH
PAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQTKDKITGYLGKAKHLGLKNIMAL
RGDPVGADWEEEEGGFNYAVDLVKHIRSEFDDYFDICVAGYPTGHPEAESYQQDLRHLKE
KVDAGADFVITQLFFRAETFLKFLDDCRTIGITCPILPGIFPIQGYQSLRQLVKLSKLEV
PEEITSILEPIKDNDAAIRNYGIQLAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQL
GLWTEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPA
FGELNDYYLFYLKSKSSKEALLQMWGEELLSEESVFEVFTFYITAQSNRCGQKVLCLPWN
DEPLAQETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFF
TSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVD
PVSFMSWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWQVI
DDMFELLDSPAAPPCEDATP
>A0A1S9DSA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus oryzae|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNRDFTFAVDLVRYIRQKHGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYL
VEKTQAGADFIMTQLTYDIEAYTRFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVQIPPQILAKLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLRGFHFYTLNLEKT
VSFILERCDLIPPYSEDFDAIEEGGDISAMDGAHLRSLTRRRASSINSLPHNRVIVDKLH
ASEVSSKASVSHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSS
GLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRSDDPVYGWGPPREGFVFQKPFVEFF
CPSKDYHSILKPLLQKHGHEKLAWFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWG
VFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNDIKDDVWLVCVVG
QDFGAGTEMGSEEEEDEKKFMWRVLLNAKK
>A0A0Q5EEP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Leaf127|TrEMBL
MSQKHVYSFEFFPTKTDAGQEKLLSVARQFRACSPEFFSCTYGAGGSTRDRTLNTVLQLQ
NEVKVPAAPHLSCVGDSKDDLRGLLAEYKAAGIKRIVALRGDLPSGMGLVSGDLRHANDL
VSFIREESGDHFYIEVAAYPEMHPQARNLEDDIANFVRKVKAGASSAITQYFFNADSYFY
FVERVRKAGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYNDDSASIQAFG
EQVITEMCEKLLQGGAPSLHFYTLNQAEPSLAIWKNLESSR
>A0A5N6TUS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus avenaceus|TrEMBL
MEKITDKIAALPPDSNYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGTT
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIREKYGDYFCIGVAAYPEGHPVDTYQDVQDPKRDIPYL
VEKTQAGADFIMTQLTYDIDAYTKFETMLRDHESGVFKTIPIIPGLMPIHSYKILTRVTK
LSHVKVPPHILSKLEAIRHDDDAVKRAGVDIISDIVDGIRDIICPGIRGFHFYTINLEKT
VSFILERCDLIPPYTECDAVEDDTSLSVMDGPQMRSLTRRRASSISSLPHNRVIVDKLQA
SDVSSKDSVSHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVPPSIAHRIWGYPVTHDDISKLFRRHVSGELHMVPWSEGGAEEGTPA
LNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRSDDPTFGWGPPREGFVFQKPFVEFFC
PNSDYQSLKAILQGHGHEKLAWFAANAKGDFESSLPAQTSDADPIEMNPDNVNAVTWGVF
RGKEIVTPTIIEEVSFRAWGDEAFRIWEEWRRIYPRNSATERFLQEVQNDVWLVCVVGQD
FGAGTEMGSQEEEDERKFMWRVLANAKQTA
>A0A0B4GS82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium guizhouense (strain ARSEF 977)|TrEMBL
MHIKDMLAEAEKGGQPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLEKVNAALQKAYKAGCTNILALRGDPPRAQEK
WTAAEGGFHYARDLVKHIRATYGDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGKVRERGINIPILPGIMPIATYASFLRRAKHMQCKVPDHWMTAL
EPVKNDDVAVREIGKTLVAEMCRKLLANGIYHLHFYTMNLAQATRMLLEELTWAPCAERP
LQQALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTTVQDIASIFVKYLNREIESLPWSEAPLTGEANAIKDNLIQ
LNKRGLLTINSQPAVDGVKSSHPIHGWGPSNGYVYQKAYLELLVPASIFTEMVKRVEDKP
TLTYYAVTKDGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGTDW
AHCFESETPSRVLLDQIMNEWYLVNVVNNDFHENQTIFDLFEGLEVKGLDTPVAV
>A0A371DV81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polyporus brumalis|TrEMBL
MKLSDKIAQRDARSLFYTFEFFPPKTDQGFENLVARIARMIALHPLAVSVTWGAGGTTKD
RTLDLAGLTQIEYGADTILHLTCTNMVQGTVDEALREAKERGIENILALRGDPPRGAEHW
IPTDSRFQHGVDLVRYIKSTPEFADFCVGVAAYPDGHPDRETDEDGELEHLKEKVDAGAD
FIITQLFYDVDVFLQWIQKVRAKGITVPIIPGIMPIQTYASFLRMTKLCGTRVPPKMMHD
LVPIRHDDQKVKEYGVKLAVDMIRQLQAGGIQGVHFCTLNLEKSVIRVLETLGLAGNVSQ
ATNKLIADVATLPERTMTPHAAADRATKELTSVPAPESDAGKGEINNAADWDDFPNGRFG
DFKSPAYGETDRWGSSAFQSKATTAPVSHWGNPKTVDDLTSLFLRYLHSKVTTTPFSSTP
LSPESLMIFPHLERLTSKGWWTVGSQPPINGAPSTDEVVGWGPRGGYVYQKCFVEFFVEQ
KDVERIVKKVEEEGAGWISYFAGNAKGELLTNVPEGGRNAVTWGVFPGQEIAQTTIIEKE
SFLSWKDEAFSIWSEWASFYPPGSQERSLLEGISNDRWLVSLIHHDFLDPSALWTFLYKG
NKPLL
>A0A3S1HA14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.T.Ca.TU.009.01.3.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETAIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGG
PYRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVER
>B2VI95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)|TrEMBL
MSFFHANQREALNQSLAEISGQINVSFEFFPPRTGEMEDILWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAGDYWNNGIRHIVALRGD
LPPGGGRPEMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMTSMFA
GLDDDPETRKMVGANVAMDMVKILSREGVRDFHFYTLNRAELSYAICHTLGVRPAPAPML
EAS
>A0A371DEF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polyporus brumalis|TrEMBL
MKITQKIDQAAKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
DLTSELVKTCQKLIGIETCMHLTCTGMPKEKVDIALREAKQHGCRNVLALRGDPPVGKEW
EAVEGGFQYGVDLVRHIRKHYGDYFDIAVAGYPQTHRLPPEEAAREMQYLKDKVDAGANF
IFTQMFYDIDMFVEWVRAARAAGITIPIVPGIMPIQTWNGFQKATSLAKITVPRAFLDEL
EPHKNNDEKVRELGTKLVANMCRQILAADIGIKGLHFYTMNLEKGCRMLLEELNLVPRVE
VVKPLPWRQSLTPNRRTETIRPIFWANRTRSYLSRTENWDEYPNGRFGDSRSPAYGELDG
YGVWLKQSKEDALKLWDTPTSIDDIHALFAKFCVGQLQALPWSDTAPSSETTVIAQQLAK
LNELGFLTINSQPAVDGARSDDRIHGWGPANGYVYQKAYLEFFVPPELLEMLIPHIERDI
NITYYVINNRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGRQW
AKVYDPESPTRKLIDEIMDTYYLVNVVHNDFKKPEAIFEPFFKAGAEYAAKRGAPTANGT
ATNGHAH
>A0A0D0MWK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax paradoxus|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYVRKPQFCSVTYGAGGSTHQGTFGAVQEILGE
GVDAASHFSCIGATKATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFHYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
VRKLGIDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLCDGGAPAIHFYTMNQSAATLAVLERLD
>A0A679JQR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax paradoxus|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAARQQLYARKPQFCSVTYGAGGSTHQGTFDAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFVYASDLVAFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFATKVKAGADSAITQYFFSPEAYFRFVDE
ARKLGLDAPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVV
TELCTRLQEGGAPALHFYTMNQSAATLAVLERLD
>Q3J7R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 / C-107)|TrEMBL
MQPQQNNPLIFSCEFFPPKGEENASKLRRVRRKLARIHPRYYSVTFGAGGSTRDRTFETI
LEIQAAAKETGIEAAPHLSCVGSSRKSIREVLQAYQHQGVKRLVTLRGDLPSGMVDPGDF
HYASQLVEFIRAETGDYFHIEVAAYPEVHPQARSAQADLINFKHKVEAGADSAITQYFYN
VDAYLRFVERCKSVGIDLPIVPGIMPINNYVQLARFSDACGAEIPRWLRKRLEDFPDPAT
MSAFAIDVVSDLCYRLLEAGAPGLHFYTLNRADPTLAIWDNLGLETQPANLSAVTKI
>A0A6N6P839|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MTATGSLLDSLKESILCGDGAMGTLLAERGIPAGSCFEELCLSRPELISEIHREYLDAGA
RIITTNSFGANSLKLAPFGHESRVTEINREAAALARKAVDDSGARAWVAGSVGPIGLRGN
EAAGRGLRWEDLFREQIAALLLGGSDLILLETFQDPEELTLALSIAKSLGREFGDRPVVT
LIASPESGRLPGGAWIGDLLESLEEQGADLVGLNCVNGPQAMLRLVEKIAPTRPLAVFPN
AGRPSYQEGRISYGTSPEYFADLGRRMAEAGATLIGGCCGTSPRHIAALASALTGLSPVA
GKSHGTVSLNEESVAPLLQETSILDLIAAGKTVIVTELDPPKTLPLERFFAAAEALAKAG
SDAITLADNSLAILRVSNFAVASMLKQRGITPLLHLSCRDSNVIGLQSELLGMAAMGMRH
VLALTGDPAKGGDHPEATSVYDVNSVGLLEIISRLNQGYTQAGTDLQAKPCLVAGCTFNP
NAKNLDTQVQRLERKIRAGATYVMTQPVFETSLVEETARRTAHFGVPVFVGVWPLLNGRQ
AKFLHNEVPGILIPERVMRRMEGLEGPEGRKEGVEIAKEVTRSVLDHFPGVYFMTPFLAY
QTTEELSAFVRSR
>N9FT85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii ATCC 9957 = CIP 70.31|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHNVAGIVITPHMLRALAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVKT
KNELVPELAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDLCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A8D9ZFF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus Btn1260|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A7X2P4W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oliverpabstia intestinalis|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMFGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLEEGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMVKFMNNNVAGIHVPDEMIEE
LKADKERTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A2V5MZG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHGMNLLEELQEHVVCGDGAMGTLLLDQGLPMEACLEEISVSDPERVCAIHRDYIAAGAR
VIETNSFGANAARLARFGLEDRVAELNKAAARIAVEAAHGHDVCVAGSVGPLGLSALDAE
ERGIDRAKCFREQIEALLDGGVDLIFLETFMDDAEMQIALRAKKSVSDCATICSFACEPE
GRLASGVSIVEAFSKLRAAGVQITGVNCMNGPHATVQLLQRIPIEGLLAAYPNAGYPRYT
EGRFIYHAAPDYFARAAREMVGEGARLIGGCCGTNARTIAAIAKSIENLTPVKSKPVRVI
APLPTPTKKIVSAEEESLLDKIAAGKRVIICEFDPPKTLALEKFFQGAQELVQAGCDAIT
LADNSLAILRVSNLAIGAMLKERFGITPLLHLSCRDRNVLGLQSELLGMAALGMRHVLPL
TGDPARVGDHPGASSVYDVNSIELISIIKKLNEGFTHAGKSLKTQTRFIIGCTFNPNAKN
LDSQVNRLERKVAAGAQYVMTQPVFDVELVAETKRRTAHLSIPIFIGVWPLMSSRQAEFL
HNEVPGIIVPEEVRKRLANVPAEDARTVGIKIAREITENVLTHFPGVYLITPFLNFESTC
ELAQFARKV
>A0A7Y4N3N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus coralloides|TrEMBL
SAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFEGLDNDAETRQLVGANIAMD
MVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A7K0E9E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kriegella sp. EG-1|TrEMBL
MKVTEHIEKAKGKTLFSFEIIPPVKGRNIQELYNNIDPLMEFKPPFIDVTTSREEYIYID
RAGLLDKKLTRMRPGTVGICASIKHKYDVDTVPHVLCGGFTKEETEYVLVDCHYLGIDNV
MALRGDAMREQQYFEPTKGGHKYALGLVEQIQNLNCGKYLHEVIETDDCADFCVGVAGYP
EKHMEAPSLQTDLKRLKEKVEAGADYVVTQMFFDNKKYFQFVEAAKNAGINVPIIPGIKP
IAVKRHLNILPQVFKIDLPQDLIDAVDDCKDNKAVRQVGIEWAIQQSKELKKAGVPSLHY
YSMGKSDNVHAIAKALF
>A0A496PZP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MGTLQSKLLETSDFLYGVELVSTRGSMSDTTAIATRNYANELIACDQLDWVSITDNAGGN
PMLAPVALAKPILYAGKEVVIHLSCKDFNRNGLESEAWFLASEGFNNVLVLTGDAPISGN
EGVAKPVFDIDSIGLLTLLGKMNEGMAIPLGRSKRTKRLERTNFLLGAVTTNFKLHENEV
IPQHLKLEKKIEHGAQFIINQVGYDSRKIHELTAYMERKGIGNVPLIGNVFVLNRGVARV
FNAMRIPGVVVSDALLETCEKQARSPDKGKSFFLELAAKQIAVYRGLGYRGAYLGGVHRF
EDLDRIFAIERTFGAEDWVTFAREIRFSRPGEFFTFAENPDTGLADPDRLEPNYEASLKR
RQKTRNVTLNYRVSKWAHGAIFESGTFFAKVGGRLCEKSRDPKNGPKWLRAIEHLSKAAL
YQCMDCGDCSLPDVAYLCPESQCAKNQRNGPCGGTRDGKCEVHDFECIWARAYDRMKYEG
QDQKLLDHVPVIQDQGLRGTSGWANNWLGRDHFAPKEPDNAPDKELTTKRKIEKKEEKTN
GD
>A0A2V5SAC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
HDQIEALLDGGVDLVFLETFMDDAEMEIALRAKNSVSDCPTICSFACEPEGRLASGVSIV
EAFTKLRAEGVQVTGVNCMNGPHATVQLLQRIPIEGLLAAYPNAGYPRYAEGRFIYHAAP
DYFARAAREMVAEGARLIGGCCGTNARTIAAIAKAIQNLTPVRSKPVRVITPLPAPAKKI
VSAEEESLLDRIAAGKRVIICEFDPPKTLALEKFFRGAQELVQAGCDAITLADNSLAILR
VSNLAVGAMLKERFDITPLLHLSCRDRNVLGLQSELLGMAALGMRHVLPLTGDPARVGDH
PGASSVYDVNSIELISITKKLNEGFTHAGKSLKAQTRFIIGCTFNPNAKNLDSQVNRLER
KVAAGAQYVMTQPVFDVGLVAETKRRTAHLSIPVFIGVWPLMSSRQAEFLHNEVPGIIVP
EGVRKRLAHVPAEDARAVGVEIAREITSEVLAQFSGVYLITPFLNFESTCDLAQFARNV
>A0A2T5JE20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter yixingensis|TrEMBL
MKITEHIANANGKTLFSFELIPPLKGHSIQGIYNAIDPLMEFNPPFIDVTSLREDYIYKQ
HNNGLLEKLTYRKRPGTIAICAAIMNKYKVDTVPHMLCGGFTKDETENALIDLQFLGIEN
VLVLRGDARRGDATFVPNNNGHCFATDLLQQVVDMNNGVYLHEDSDSHIMHTDFCIGVAG
YPEKHFEAPNLKTDFKYLKQKVEMGANFIVTQMFFDNQAYFDFVKKCRENDINVSIIPGL
KPITNSKQLVSLSKTFHIDIPEELSDAIHGCKSEKDVKEIGIEWMINQCKELVKFGAPVL
HFYTMGNPEPTKRIASAVF
>A0A2V6MRG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMLRESPTFSFEFFPPRTPEAAEILYHTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIEAILIRYTKSAIGNILALGGDRPRGIDYDKAR
DSFQHAIDLVKFIRKFNESGAHPDRRGFGIGVAGFPEGHPATPNRLLEMDHLKAKVGAGA
DYIVTQLFFDNRDFYDFRERCALADIHVPIIAGIMPITSVSGLKRIAELAGGARFPARLL
RALQRCENDPEMVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRIIFDSLGIPRRR
SAQAQTV
>A0A3E1EPZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHILDIFAKQATTFSFEFFPPKTAEGAQALFETIRQLEAFRPDFVSVTYGAGGSTREVTH
ELVVRLRKETSLDPVPHLTCVCHGEEDITAILERYAEEGVGNILALRGDPPKGRGDHDWS
RDAFRYAAELVAHIRRFNERGYHPDRRGFGIGVAGFPEGHPLTPNRLVEMDYLKAKVDAG
ADYICTQLFFDNHQFYDFRERCELAGIRVPIIAGIMPVTTTQGMRRMAELSGGSVFPARM
LKMLARAGDDAEAVRRVGLHYAAEQCADLLHHGVSGLHFYTLNQSSATREIYASLGLRGN
>A0A0Q6F9G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmoricola sp. Leaf446|TrEMBL
MSGTPARIGDLLGSGQRSFSFEFFPPKDEAGEDVLWRSISELEPLQPSFVSVTYGAGGTT
RDRTLAITARIAQETSLLPMAHLTCVGHTTAELLDILAALRGSGVGNVLALRGDPPGGPG
TPFEPTPGGVDYASELVGLVRRSSDLCIGVAAFPEGHRDAATLDDDVAVLRAKQDAGAEF
AVTEMVLRASDYLGLVERAGAAGVTIPIVPGIMPILGVTSMTKMVELSGRDIPAEVRSRI
EPLAEDPAAVRAEGIAIATELCDDLLAGGAPGLHFYTLNRSKATREIWSALSLSA
>A0A3S9KR21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira mayottensis 200901116|TrEMBL
MKKVSEIYSSAKGPVYSFEFFPPKTLDGDLKLMETVKELAHLDPDFVTVTYGAGGSTRDK
TAQILSEISKNYSFPTVSHFTCVGANQEQIFKALKEIRSSGIVNLMALRGDPPKGEGKFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPNAKSLEEDVENLKRKVDAGTDFLVS
QLFFMNSIFENFLNLVRKAGIHVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A397YA56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica campestris|TrEMBL
MKVVDKIKSATEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNVICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGEDK
FVQVEGGFACALDLVNHVRSKYGDYFGITVAGYPEAHPDVIEADGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRKIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAFGIHFATEMCKKILAHGITTLHLYTLNMDKSAIGILMNL
GLIDESKITRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYGTLSDYQFMRPRARDKKLQQEWVVPLKSIEDVQEKFKELCLGSLKSSPWSELDGLQPE
TKIINEKLGKINSNGFLTINSQPSVNAAKSDSRAIGWGGPGGYVYQKAYLEFFCSRDKLD
TIVEKSKAFPSITYMAVNKAGNWVSNVGEADVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYFLVSLVDNDYINGDIFSVFA
>A0A2V5V4F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
TQLFFDNRDFFDFRERCVLANIHIPIIAGIMPVTSIKGFKRIAELAGGTRFPAKLLRALQ
RCENDPEMVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRVIFDNLGIPRRRKVQA
PTVPSSDEVRKRLAN
>A0A2V5NCH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHISDIIQTGSPTFSFEFFPPKTPEAAESLYQTIRELEEHMPHFVSVTYGSGGSTISPIS
DKSSARLAS
>A0A368B9K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIKDIINKGQPSFSFEFFPPKSDKSSDELLKTIKDLEPLDPSYVSITYGAGGTTRERTH
ELVEKILDLTNLVPIPHLTCVQHDDEEILRILNRYCDKGVSNILALRGDPPKGNNNYDRS
HDTFQYACDLVKFIRGFAKNTKSLGIGVAGFPEGHPETPNRLKEMDYLKAKIDSGADYIC
TQLFFDNHDFFDFRERCILAGIDVPIIAGIMPISSMQGLERMANLAGGSRFPAKLLKSLR
RCDSNPASIEKVGIQYATEQCSELLNNEVEGIHFYTLNKSEATKGIFESLGINKTSK
>A0A1X1IG70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLQTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1G3CA60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RIFCSPLOWO2_12_FULL_40_19|TrEMBL
MSENNDTNNFKAGSNLEKLLRRGEFVVTSELGPPRGASREAVEKKAEILKGYADAFNITD
CQTAMVRLSSIASGAILLNMGMEPVIQMTCRDRNRIAIQSDILGAAGLGMKNLLCLTGDH
QCFGDHPDAKGVFDVDSIQLLDIVRQMRDEKRFQSGEELKVEPRLFLGAAANPFADPFQF
RAIRLAKKIKAGADFIQTQIIYNVEKFEKWMGIVQDMGLHKKVFILAGVTPIRSLGMAKY
MKKSVPGMDVPDEIIKRLEGAENKQSEGINICLEIIGRVRKIEGVSGVHIMAVEWEEIVP
EITERAGLLPRPTP
>A0A5E4KB58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon|TrEMBL
MSFREKLTSGKFTVTAEISPPKGTDITGMMKEAGMIKDVVDAVCVTDNQRALMRMNPLAA
CSALSHEGFETIMHMTCRDRNRLALQSDLLGAANLGIKNVLVMSGDYPTKGDHAGAMPVY
DLDPVQLLGMISRLNSGFDLSGNSLLGKTDFFAGAVSNTELTEAAFIKLGKKVKAGARFI
ITQAVFDAGKFSGFMDKFQSAGGKQIRVIAGIIPLRSEKNAQFLNSNIAGVKVPDGVIRR
LKSASSPGDAGIEMAADLIKELRGVCDGVHIMPVGTHENTRKLLEMAGI
>A0A8B3LIT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.07.2.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGG
PYRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A5E4HPQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon|TrEMBL
MTLRKKLAAQQFVVTAELTPPKGTDIKPTLEKLEHLKDADAINITDNNRSIVNMSGLAFS
ALLVSRGKEPVYQITARDRNRMAIQSDLMGAHALGIHNILALHGDDPSKGDNPQSKAVFD
LDTLAILSAVSALNEGSDLAGNKLNAPTDLFPGAACDPNKKIEEELARMQAKRNAGARFF
QTQIFYEADKFSKFAAETSSLEVPILAGITPLKSEKMANFLNEKVKGVHVPKELIQEIKE
SANPEETGIEQAARLIKDIKDDCAGIHVMTIGGEKNLPKLLKLAKI
>A0A8B3LMV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.07.2.1|TrEMBL
MIGRQIDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRSYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
T
>A0A271VU07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio metoecus|TrEMBL
MGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWNSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWNNGIQNIVALRGDI
PAGGGKPDMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPNWMVKQFEG
LDEDPVTRQLVGASQAIDMVRILCREGVKDFHFYTLNRAEMTYALCHTLGVRPQV
>A0A5N8YGK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium AC-409-J13_OGT_754m|TrEMBL
MGPRPTLSFEFYPPKLQEGIPSVFKSIDKLKEFSPDFVSVTYGAGGSTQSLSEQISIRIK
EQTDLVVMAHLTCVSQTKTDVHNVLTRLADAGIQNIIALRGDPPLGQNEFIANKDGFSHA
NELIDHIRTNFEFGIAAACYPEGHSESTNLELDLEYTKRKVDAGAQFLVTQLFFDNAYFI
NFLNRARQIGINVPILAGVLPILRTEQIRRFTAFCGATIPDSLGQQLNNLSHDAAAVREL
GIEQSTNQVMDLMEKGIDGIHFYALNRSYSISRILSNIGWVKSANISR
>A0A2N3FSJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium HGW-Actinobacteria-5|TrEMBL
MPGPEPTIADVLAAQDHPTMSFEFFPPKDDAGQTQLLDAITALEPLRPDFISVTYGANGS
SRARTLAATRLVQERTTAITMGHLTCVSQSTEELRAAIAAYAEAGVRHVLAVRGDPPGGP
TAPWQRHPDGLDNATQLVELVKASGDFCVGVGAFPDGHPEHFDVDLDARILAAKEQAGAE
FAITQLFFDADAYFRLVDRVRALGCTLPIVAGIMPVTNLGQIERFATLSGADLPAPVVTR
LHAVADDPSAVRAVGLEIATQLSDRLLAGGAPGLHFYTQNRSKATAEILARLREIPPHLD
QLGDGS
>A0A5F0EDY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT1-3|TrEMBL
MTATGISACNDRPAFSFEVYPPKSVAAASALTRTIDHLAAAGPEFISVTYGANGSSRTSS
LDVLRYIKDHTTADAMAHLTCVGSSHAEASRLIREFLDAGIRSFLAIRGDAPQGAAEGDT
TFLGDLHSAGELVQLIHRVQAERVPYIETVIPGLPAARGLKTERSRVRIGVAAFPNGHPN
SRSVAQDIDTLLAKQAAGANLAITQLFFHADDYLSFIQKARSAGVLFPILPGIMPVTSPN
RLRRILQLSGEKLPAALSIALEVEPTEEGQRQIGIDYAVRLGQDVLAGGAPGLHLYAFNQ
HETVLSVLEGCGALPVPATMP
>A0A7W3KXN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter ciceronei|TrEMBL
MPEPKHRLSPENSPNLVAEGVSLELAPAQAAGFLPLETAFPEGSRVFLTHLEGKPLALQV
EAARQLRQAGFVPVPHFGARHFASPKEFVDLVGAHSRNGVTEALFVGGNPLAANGPLEDA
ADLLAHPVIADSTIRTAFIGGYPEGHPAIGRSALAHALLRKIAICHDRDLAPRIVSQFAF
DGAMMAAWTNDLHRAYPGIPVHLGVAGVTSLTKLIKFAMMCGVGPSLAALRRSGVGLFNV
LADKDPGDLVEAIETGLASNCGAQTFLHIFPFGGWEKSLSWLEEFRRRRAN
>A0A0L8INA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. aceris|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHLYTLNQAEPSLAVWNNLQLPR
>A0A3B9EPI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
TDGAEDRLWNSIQRLAPLNPKYVSVTYGAGGSTRERTHSTVKRLLNETDLLPAAHLTCVD
ATTSEIDKVAQDYWDMGVRHIVALRGDPQDTSGVYKPHPGGYAFACDLVSGLRQIGDFNI
SVGAYPEVHPEARSAKADMDNLKRKIDAGADQAITQYFFDTDVYLRFVDQARAAGIWVPI
IPGIMPIHNFKKVANFSKRCGATIPRWLIDLFDGLENDPETHKLVAASLVAEQCRTLHAF
GDKQFHFYTLNQADLTYAICHMLGVRPKPTAGDDDRAEPDNQQSKKQKAI
>A0A3N5J8N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MPTRSREFIERLRGEVLVADGAMGTALYARGFSYRSCFEELNEAHPEVVEALHREYIAAG
AQVIETNSFGANPYRLAEHGFESRVREINRAAARIARRAAGDAVFVAGSVGPLNRMLEPI
GTLTLSEARAAFRIQVTGLLEGGVDLFIVETMSSLAEICEALTAIRELCDLPIVASMTFT
EEGKTLVGDKPGEVKRVLLDAGANVVGANCSVGPQPMLDVIERMGGDVLLAAQPNAGLPR
LVGGRYVYLTSPQYFADYALKFAEAGVCLVGGCCGTTPDHIRAIAKAVKGQKPNVAREIV
ISDLEVEVPVETTAGGVAASDFRADLGKRFLISVEIDPPRSINPEPFIRHAQMLKANGVD
LINVADSPLARSRLSALAMSHLIRREAGMEVILHLSCRDRNALALQSELLGAHALGVTSV
LAVTGDPPAVGDYPFAKAVFELDSISLCRLVSQLNLGKDLTGRNMEEPTRFLLGVGVNPT
ATDRVLEFERFHKKIDAGAQFAFTQPLFDRDTLDKFLNDVASFCTIPIFVGIMPLRSAKH
AEFIHNEIPDMFVPEDIRERMRNSGTEGAKVGVEIAQKFLLDVKPIVQGAYLMPPFNKFE
MAVEVIRVLEERMKDKG
>A0A7Y5K6N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MLTPFLQRLQEDLLVADGAMGTMIYSHGIPLSQSFDQLNLTQPDLIRNIHRAYVEAGAEA
LETNTFTTNRHRLARFGLEDKVRELNHAAVRLAREAAEGRAYVLASIGPLRDRASEDLEL
AACREIFAEQISALAEAEPDALIFETFMAVDELELALEQVRRLTNLPIIAQVVVDDAGYT
RDGLHLTVGFRHLREAGAHVVGINCAKGPNGIIAALREVPLADGLILSAFPNAGLPAYVD
GRYIYLSTPEYFAESSRKLREQGVRLIGGCCGTTPEHIRAMAEALRGLKPVTAKHVTPHI
TPTPPRAEKITTPEFLQNVKKRPTIIVELDPPRDLGYEAILTGARELKRAGVDALTMADS
SLGITRMSNLALGHLVEEQAGIPVIIHLACRDRNLVGTQSELMGMHALGLHTVLALTGDP
AKFGDQPGATSVYDLNSFSLIEMIKRMNQGIAFSGRAMQERSRFTVGVAFNPNVERIDTQ
VRRLRRKVEAGADFVMTQPIFDWRQAREVYEATREFEIPIFVGIMPLTSGRNADFLHNEV
PGIQIPERVRQRLFRFEGERARREGVTIAAEILESVLDYFNGLYLVTPFVRYEMCVELVE
VCRRLVRRKM
>A0A7S4K123|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odontella aurita|TrEMBL
KPETMDEPPLSSRLSNPSRPVFLLGDVPPMEGTPPGKAQLICNKFMHRSRALASDGFVVY
DIQDEAGRSDAERPFPFRRLMDSSGYAALLSRSSGKQCLVYKCVADRKFEGWLDRAASDH
GHSAINLVGRATSEGEYQGPTLSEAMEMVSERASGPRSIKFGCVCIAERHTMEAAASRGK
PYPTEHQNMLRKQKAGAEWFISQAVYDPEPTIRLLRDYAALCREQGVMPRKVVLTFAPVS
RKKTMNFIKWLGVTVPPEAESKILEAERPVDASVDLLCDILGTILRECAGIGVPLGVSCE
SVSIYKAEIDGVHELFRRLQEILLDGRGSPWKVQWVEVMPPAGVSREERALAKQERQLMG
AASGGSEYAIATAGLVGVLLGGLLVSAGVVLDGRRRL
>A0A6N7M699|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaeta sp|TrEMBL
MSFSENLASGKFLVTTDVIPPKGVSFSEALARLDCVAGKVDAVNVVDLPSSAMRVSPLPV
AVVLKKRGFEPILQMTCRDRNRLALQADLLGACMLGIKNILALTGDEMDLGDDPAAKPVF
DLDSIGLLKAAAQLEEGRDLAGNALTGSPAFCAGAAVDPFGSPVGREITRMRQKVEAGAK
FFQTQPVFDAEEFGAFMEKIGKPGAPVLGGILLLKSARMARFMNENIPGVEVPRHLIQKM
ENTKYPVETSVEIAGRLINEIKGICSGVHIMNINWEDKIPLVLEAAGLT
>A0A1N6A8C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus subsp. bolletii|TrEMBL
MTTNPLDRDGPVAELQDPGSIADRLTAVQPGEIAFSVEFMPPRDEAAEARLWRAARVFER
YRPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEERLLRAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTARG
>A0A7V8A2U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus agalactiae|TrEMBL
MSKFLEKLKTDILVADGAMGTLLYTYGLDTCHESYNVTHPEKVLAIHQAYIEAGADVIQT
NTYGAQRHRLKNYGLEDQVVSINQAAVNLAHQATLGKETFILGTVGGFRSQRQCDLTLDN
IVEETLEQVEVLLATGQLDGLLFETYYDIEEITTVLKIVREMTDLPVITNISLHEAGVTS
NGKPIVEALSQLVMLGADVIGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASQLSLDGE
NSQYQFSQNSEYFGKSAELLVAEGVRLIGGCCGTTPDHIRAVKRSIRGLKPIERKVVTPI
IPVKDFVRRIRRTDTLVDKVKKEVTVIAELDPPKHLDIVQFQKAIRAIDQKGIAAITLAD
NSLSNTRICNLSIASLLKDEISTPFLLHIACRDHNLIGLQSRLLGMELLGFNHILAITGD
PTKLGDFPGATSVYDVTSFKLLSLIKQLNQGLSYSGASLRRPTDFTVAAAFNPNVKNLTR
TVKLIEKKVASGADYFMTQPIFDHSVLKELADLTKTVEQPFFIGIMPITSYNNAVFLHNE
VPGIKLSESFLSALEKVKDDKEACLTLALNESKSLIDEALNHFNGIYLITPFLRYDLTLE
LIDYIQKKQVRKSS
>A0A2Z7A1S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorcoceras hygrometricum|TrEMBL
MGGTRAEIRALLDGYKAAGYRRIVALRGDLPSGMASAGDFRYAAELVSFIREHSGDHFHI
EVAAYPEIHPQADDAHADLHHFKAKVDAGANGAITQYFFNPDAYFRFVDDVHRLGVRVPI
VPGIMPIANYTQLKRFSDACGAEIPRWIAKRMQAHGDDAASVRVLGAEVVAQLCRRLLDG
GAPGLHFYTLNRARATRAVLEQLD
>A0A7L0D090|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rostratula benghalensis|TrEMBL
MVNETQHTCSASSSSKSDCGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFVITQLFFRSKTFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYEFRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVMDDTFELLN
>A0A0H2ME99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiloniella spongiae|TrEMBL
MSTEFNPEVVKQQIIDFMTGFTIETTPGSASKTPDYRVHLRPGTEIAVTFLPGSDFADTV
STSKRLKDEGFIPLPHFAARSIRSRNDFEEYLKTLQGEVGIEHAVALGGAVDKPLGEFES
SMQLMETGLFDKYGIKSIGVAGHPEGSPDINEAGLREAIAWKNAFKEQTDAYMYIATQFC
FEAEPIIAWDKKIQAEGNKLPIHLGVPGLATLKTLMNHAKACGIGSSMRVLTRQAKNIAK
LMTVNAPDKLVMDLARYHAEDPTCGIKKVHMYPLGGMKKSAAWSYAVTDGDFTVDPKGKG
FKINRDIG
>A0A2E7F4K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MGFTADVRVSFEFFPPKSEKMERALWLSVERLAPLGPSFMSVTYGAGGNTREKTHEIVSR
LQAETGIPTAAHLTCVGASTDEIHDIARRYWDAGIRHIVALRGDPPDGHPVYQPDPDGYL
YAADLVRGLRSIADFEISVAAYPETHPEARSPGADLDNLKRKVDEGARRAITQFFFEPDV
YLKFRDRAAASGITIPIVPGILPVTNFSQVMSFSKLCGTSVPVWMADWFDGLDEDPGTRQ
LVAASVAIELSRFLVSEGVEDIHFYTLNRADLSYAICHVLGLRPNQPKNE
>U6ZUI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aestus|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASCNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKVPSAPHLSCVGDSKDDLRGLLQQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VNFIREETGSHFHIEVAAYPEMHPQAHNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVQKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
TQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2A5EUF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MSSLGDRFRGRDDVRVSFEFSPPKSDEAEEKLWKAIKRLAPLNPAFVSVTYGAGGSTRER
THSTVKRLVNETAMKPAAHLTCVGASRSEIDGVIQGYWDAGVRHIVAIRGDMPNMEGAYR
GHDQGYGSTAELVRGIKSIGDFEVTVSVYPERHPESRDFDHDMDLLKEKIDAGATRAIAQ
FAFETEHYERLLERLAKAGTTIPIIPGIMPTTNFKGVVRMAERCGATVPGWLSSYYEGLD
EDLATRRLIAATVSAEQVHDLERLGFRDFHLYTLNQADLTYAICHILGFKPAAAS
>D5UFR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas flavigena (strain ATCC 482 / DSM 20109 / BCRC 11376 / JCM 18109 / NBRC 3775 / NCIMB 8073 / NRS 134)|TrEMBL
MSVVAETGTVPAAPSAPGRARAARRRAEQAGALDRPTVSFEFFPPRNPDAAPRLWETVRA
VETVEPDFVSVTYGASGKTRETTRAFVRRLLRETSLNPIAHLTCVGTSRTEVSTIVEEFL
DEGVRSFLALRGDPPVGQPDWRPHPEGVHTAAELVELLRDLEQRRCGRSPAQAVRARVRP
LSVAVAAFPRGNHATGGTRAQDVQALLAKQEAGADFAISQLFYDAEAYLGLVAEARQAGV
TIPIVPGIIPTTDPARLLRVQELSGVPVPRHLLDLLGSTDDPVERHRRGTQAGVDLVNAV
LDGGAPGVHVYTFNKHEAALDLLDGADLLDGRRCAVTPHDPSGGTPAGATATTPRGNLS
>A0A1G9UMR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus siccatus|TrEMBL
MQGGPDSGGSVSSLSMTRTVRELLAESRPTWSFEFFPPKSPEGATQLWTALRELERLQPS
FVSVTYGAGGSTREGTVSVTERIATETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNL
LALRGDPPGADPQAEWVAHPEGLTYAAELVELIRSMGDFSVGVAAFPERHPRSPDFETDV
EMFVRKCRAGADFAITQMFFRPEDYLRMRDRVAATGCEVPIIAGVMPVTNARQITRIVQL
SGQAFPEHLAARFAELDGDTPEARAAVRAYGVEVATELCRTLLDEGVPGIHFITMNRSTA
TREVHANLVAVPAPH
>A0A1A3MMY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. 1245852.3|TrEMBL
MPADSGCPKRMEFGPCGGVRPDGQCEMRPGPCVFDDVVPWSGHSPAPRPARTPRVLTDFS
ATPFDPDDIAATATVLAPGCDAVLVGEHQNKPDFPPTLMASLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSIDVETVLCVTGDGRGYDVRPDVSQAFDLDGPRLVSLAASVGIVAAVP
ETPTAPPVQRRPARLVEKQRAGASLAVLNHVPFPDMVADFMKSARAAGLAIPVIAAVAVF
TDTVSAAVLEGLPGLELDPTVTQRVLGASDPVEAGIAAAVDEARALLSIEGVEGVNVSGL
ASASGPRIGAEIKAEVGRRIREQGGGAP
>A0A660YLY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MSLKNLIKSDKFIVTAELGPPQSANRGVIERKAGYFKGFVHAVNITDNQTAIVRFSSIAA
AKILIDSGLEPVIQMTCRDRNRIAIQSDLLGAFGLGIENVLCLTGDYTTSGTQPEARPVY
DMDSIQLIASVSRMNRGTLLSGDPIKTPTGFCIGGAANPFAPPFEMRIIRLQKKIAAGAQ
FIQTQPVFDLEIFKKWMERVNGLGLSKKTAILAGVMPVKSVKALEYMKSQVPGMRIHPSF
IKRMAESEDPKAEGVNIAVELIEQIREIPGIRGIHLMPLMWESITPEIIKKSGITIDK
>A0A496T5W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MKIIDMLLKDQFTLSFEVFPPVREGNFDSLYSTIEELIKINPHFISVTYGAGGSTRDKTV
EIASRIKNEFRQEVLAHLTCDQATAEDTAKILDTFKAENIENVLALRGDPPKEEKAFLKP
EGGFGHANELVEFIKMKDNFSIGVAGYPEGHIEAPNLDADITNLKRKVDAGADFIITQLF
FNNDDFYRFRDLSIAKGIRVPIIPAIFPIFNYKQISKIASLCGAKLPSKLHDKLCKVSDK
SEEVEKYGIEYATSQSEKLLNNNIPGLHFYSMNRSRHVIQIIRELHLPIQKPAPISE
>A0A413PW27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum hallii|TrEMBL
MNTMQTNPQDILKTLSLSFEVFPPKKWEDFPGLYETLDELKGLHPEFISCTYGAGGSNSK
KTAEIASHIENELGIRSIAHLTCAALTEDKLLSTIENFKNAGIHSVLALRGDKPFDMSEE
DFANRQYKHPSEIIPILKKAGFRVAAACYPEKHYEAPSMEEDLHWLKHKVEQGADALISQ
LFFDNDAFYRFMDAADQKGITVPVHAGIMPITSAKMINTTINLSGASIPKALSDLIATYG
ENPSDMRKAGIEYAARQINDLAEQGMHYVHIYTMNHSETAKEICGLIK
>A0A7V4HHJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MNSESRLKRVLKENGFAVTAECGPPKGADPEVIRKKGLVLKGFVDSVNVTDNQTAVVRMS
SLAACSILRGEGLDPVLQMVTRDRNRIALQSDVLGASAMGIRNILCLTGDHPSFGNQPQA
KGVFDLDSVQLVQIVRAMRDEGKVIGGDDLSSRPDLFIGAVENPFADPVSYRAARLAKKA
AAGAEFIQTQCIYNLARFQEWMAQVRDRGLDEKVCILGGVTPLKSAKMAEYMAKNVAGMD
VPDDLIRRMASVPAKEQRQEGIRICVETISALREIKGVRGVHIMAIEWEEAVPQIVEQAG
LLPRPKA
>A0A7X6ZQ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
DYVAAGADVIETNTFGANRIKLAEFGLAEKTGEINFRAVEIARKEAGNDVLVAASCGPCI
SDSTVQTEFSSAILNEVRDAFNEQISALAKAGVDLIFLETFTDFDELLVAAKISKQYSLP
VLASISPVVFETSPVDEIVKKMDDCSDIDVIGLNCYFGPAEMFDIARKIRTLAKKPLVIM
PNAGRPHEIGGRTLYLNSPEYFTEFAKKYIEIGANGIGGCCGTTPAHIRMASRAVHVMSG
VKQHIEIADSGSAADTIQPPEALPLSEKSPFGKKIASGKPVTSVEIIPPRNHDGIEAFIE
KCRMCERAGIDAINLPDGPRASARMSVIATAATMLRSNLEIEPVPHCCCRDRNLIGMQSD
IIGGFSLGLKTWLFITGDPPKLGNYPDAAGVFDIDAVGATQLATNLNRGLDAAGQSLGAQ
IPITVGVGLNPVTVDFNREAQRFRAKVEAGAEFAITQPVFDTEVLLRFLDLLAEYSPMIP
VVIGIYPLLSAKNADFMNRYVPGVHVPEKVVRRMEQCKDRETAISTGIEIARTTRSEIES
AGFKNFQVSAPLGRTDIAIKVLA
>A0A5N6KDA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monilinia laxa|TrEMBL
MLREVADRWARKSLLEKSIFSRKAAKRLYISDNMLAEAERSGNPSFSFEFFPPKTAQGVQ
NLYDRMDRMHGLGPSFIDITWGAGGRLAQLTCEMVGVAQSQYGLETCMHLTCTDMGKEKV
DEALRNAYKAGCTNILALRGDPPREKEKWEATEGGFQYAKDLVHYIRQSYGNHFDIGVAG
YPEGCDDQDDEDLLLDHLKEKVDAGATFIVTQMFYDVDNFIDWLGKVKARGVSVPVIPGI
MPINTYASFLRRCNHMGCKIPPKWSKALEEVKNDDAAVRNIGKDLVAEMCRRIIEAGVHH
LHFYTMNLAQATRMVLEELRLTPSTHRPLKHALPWRQSLGLGRREEDVRPIFWKNRNKSY
VARTQDWDEFPNGRWGDSRSPAFGELDAYGIGLKGSNEQNIKLWGQPKSIKDIAELFVSY
LESGIESLPWSEAPISSEADIIKSDLIELNRRGFLTINSQPAVDGAKSSDPVYGWGPNNG
YVYQKAYLELLVAPDMMPELVRRIQHDPDLTYYAVKKTGDVQTNAQGDGPNAVTWGVFPG
KEIVQPTIVETISFLAWKDEAFRLGTDWAHCHSPLSPSRALIESIMDSWYLVNIVHNDFH
KSHGLFPLFDGLTVKNLSEPFEISESGDRTGRPMVTNTFNMIILSTRLYFQHDYTFNTIL
RFNMHEDGSLWFYGI
>A0A7X8XCN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MSQPAKQIDMSFSGDDRLASSMLKGEFQYYLECDTPLACQSFNASMTLIEDLGKEIRPVK
RLFGWLLTDRLLSENCHDPVLLAAALSESSGKPVIMGLSGRGSNMDRIKGMLADAKAKGL
RNFLAVTGNLTDLQQEQENLRSPFTDSVEILQAAHTFGKDIRIGATVNPFKYTPQDQCLQ
YAKMLRKIHTGAQFLITQAGWDMKKAQELQWFLQKLNLTLLVIARVCVLSQEETLRLADG
FQTGVILPVPMGSRFQQDARKSAEEYQQMQLLRAAWQITGYRKLGYGAVLISGIRNAKTL
ETLFEQIDQIEEQCPDYDSWLELWNEQYGDFNLTPTLDPHYLYWDLLQKGRRDFDPEEYP
VKGSPLPAPSLPDRCKYLLGRLLDDPGKKAWPWRTLRYITRLPEEKLAHLAPCFYLNNAQ
CPKGLRWGPCGSSQSDGTCENGKQPCFFHRVLHLAAQSNNYQVLETACWKRPPTHD
>A0A3C0KVL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophus sp.|TrEMBL
MADLIMRELGGNVLISSGAIGTCLRQASGTGDEPVELLNLRQPETVRSLHAAYRSAGSRI
LVTNTFAANTLVFGEAGVAELCEETSRAGVALAREAGGSECMVWASMGPLGLGLRLDDYT
ADTLLDVYRNQCKTLGEADALLLETFMDVREARVALQAATETGLPVIFQIGNTGGGSQRW
NRVDQLLQEAHRAGAIAVGTNCYHPDEIVRVASYIVAHTDLPVTASPNAGHPRIERGVVT
YKFTPDDFAAAAVSLSAAGVAVIGGXTDHIRRIAEVLGRRAVMSRPRIQISAKLTPALPE
RPDIADNAVRSMMKSTRFIISVEIRADRMQSLDEIVQGASKVAAAGADMFDVPDNPGATV
GRDAIITASRLQNVLKIPSICHFSVTQSNLMRLHSTLIGGWDSGLRGLLAITGDAPSMGH
MGNLAHRVVDMRSSVELLRLIRELRDGKIINGEGLADPPDFCAGCAVGRPIPAQIRWLKT
KIDAGAEFVFSQPVFTLDDYRKLRDALAGLTISLFPGIMPLVSHRSAALLANGRIPGIVV
PEDIVASFTRYDSPADQRRFGLDQACELAAAIAADASGLYLIMPFGKLCYEDSAQIVRHV
REQRG
>A0A5J5HXC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niallia endozanthoxylica|TrEMBL
MNFLKRLENEILIADGAMGTLLYSYGKDSCIEQLNLSHSEQIMDIHKAYLDAGAQIIQTN
TYAANYLKLSRYGLEDSVKEINSKAVQLAKQAVQSKAYIVGSMGGNRGINPQAISIEEIK
RSFREQLYCLLLEGVDGILLETYYDLEELETVLAIARKETDIPIIAQVSMQEVGILQDHT
TIGEALNRLESLGADVVGLNCRFGPHHMLMALEQIAIPSKAYLSAYPNAGLPAYTDGVFH
YDGDPDYFRKSAQSFREQGVRLLGGCCGTTPEHIRAFALELKDTEPVQEKALKIKEEKIV
ISTPTIEREYLPLQNIVKERPSVIVELDPPKKLDTTKYFRGVQALKEKGIDAITMADNSL
ASPRISNSALGHLVKQQTGVRPLIHITCRDRNVIGLQSHLMGLHTLGLHDLLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKQFNEGLSFSGKDLGQKTSFSVAAAFNPNVRQLDKAVQ
RLEKKITYGADYFITQPVYSEEKIISIYEETKHLDTPIYIGLMPLTSSKNAEFLHHEVPG
IKIADSIRNSMAAYKDDPIKASQEGINITKALIDTAAELFNGIYLITPFLRYEMTVELSE
YANQTSERLRRKHRV
>A0A8C1WEA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
DWEEVEGNGGKAFLCYYSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRWFSL
EFFPPRTAPGAVNLISRTNITPTLHRSGICFLNEWTFCSLCVRFDRMGSGGPLFIDVTWH
PAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMAL
RGDPIGKDWVEEDGGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKE
KVDAGAHFIITQLFFRAETFLKFVKDCRAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEV
PEEIMQVIEPIKDNDAAIRNYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQL
GLWAEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPA
FGELTDYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWN
DDPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFF
TSSENVTALLQVLKKYEPRVNYHIVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVD
PVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVI
EDMFTLLDSPQETQEEGSES
>A0A7J7IM18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanidiococcus yangmingshanensis|TrEMBL
MEPQRDPVNGSLENGCATSPISRSETPPYRDLNLREVPKVKDKVAACVEEGKRFYSFEFF
PPKTEQGVLNLYDRVARLSRLEPLFVDVTWGAGGSTSELTLELSGNIQRFFGLDVAMHLT
CTNMEEGRVDKALEDAKRRGIRNIVGLRGDPPVGQEWRQCKDGFAHASDLVRHIRRVYGD
HFCVIVAGYPEGHPAGLLDGKLTYEEELQYLKEKVDAGGDLIITQMFYDVDLFLRFVTDC
KAIGINVPILPGILPIQTYTGFKRMTGFCRTHVPPAVAEAVERIKDDEDAVKNFGIEYGT
DMCRRILKSNLVPGLHFYTLNLEKATVSILENLGLIPKFESVRSLPWRPATIDGRRFEDV
RPIFWANRPTSYLLRTEGWDEYPNGRWGDYRSPAYGDLSEHHLLGGGGLYTSEQRERIRK
ALGTPQNMNDIAAVFVKYVRGEANAPFPWAAEPLAEETKWISAGLERLNWQGFFTINSQP
RVNCAPSTDVTVGWGGPGGYVYQKAYIEFFCSKERMEQLFEVVRQNSNEFGSLSVYAINV
NGETRTNVKRPRTNAVTWGIFPDREVLQPTVVCPESFKAWSKEAFALWKQNWASVYDAQS
GTPGEKRTMALIEHIHDTYWLVNVVDNNFVSGDIFKVFARVG
>A0A5Q5EAL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. CRENT-193|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMFAADLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A2U4GFP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio campbellii|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDATRDELIDIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVVAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A1M6TS17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda antarctica|TrEMBL
MKITDHIKKANGRTLFSFEIVPPVKGKSIQELYNNIDPLMEFKPPFIDVTTSREEYIYKE
KDGLLDKKLTRTRPGTLGICASLKHKYNVDTVPHVLCGGFTKEETEYLLVDCQYLEIENV
MALRGDARKEEKYFTPTQGGHQYATELVKQIQDINEGNYLHDTIETSDLSSFCIGVAGYP
EKHMEAPSLQSDLKRLKEKVDLGADYVVTQMFFDNQKFFAFVEAAREMGINVPIIPGIKP
IAVKQHLQLLPQVFRVDIPQDLIDAVEACKTNQDVRQVGVEWAIQQSRELREYGVPVLHY
YSMGKSDNVEAIAKELF
>A0A1F9BVQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_49_23|TrEMBL
MKTKSNIERILESGQLVVTSECGPPRGADAEVIKKKGKLLQGVVDAVNVTDNQTSVVRMS
SLSACLILKEMGFDPILQMVCRDRNRIAIQSDILGAAALGINNILCLTGDHQKFGDHPKA
KNVFDMDSIQMIHTVKTMRDEGKFLGGEEIKGKPILFIGAAENPFADPFEIRAARLGKKA
KAGVQFLQTQCIYNMARFEKWMEMVRDRGLHERVGILAGVTPFKSVGMARYMKNSVPGMD
VPDEMIERLKGVAKEKQSEEGIRICVETIQKLKQIPGVRGIHIMAIEWEEKVREIAEAAG
LLPRPELA
>A0A2N9IL40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fagus sylvatica|TrEMBL
MKVIEKIREADEGKVVFSFEFFPPKTEDAVDNLFERMERMVAHNPSFCDITWGAGGSTAD
LTLDIANRMQNMICVESMMHLTCTNMPVDKIDHALQTIKANGLQNVLALRGDPPKGQDKF
VQIQGGFACALDLVKHIRAQYGDYFGITVAGYPEAHPEVIGENGLATLEDYHNELVYLKK
KVDAGADVIITQLFYDTDIYLKFVNDCRQMGITCPIVPGIMPINNYKGFIRMTGFCKTRI
PAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKQVHLYTLNMEKSALAILMNLG
LIEETKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCNPS
YGALSDHQFMRPRARDKKLLEEWATPLKNVEDIHEKFKKYCLGKLRSSPWSELDGLQPET
RIINEQLGKINIKGWGGPGGYVYQKAYVEFFCSREKLDALVDKCKASPSLTYMAVNKEGN
WISNVRQTAVNAVTWGVFPAKEIIQPTVVDPASFMVWKDEAFEIWSRGWASLFPEGDPSR
KLLEEVQSSYYLVSLVDNDYVHGDLFAVFTDF
>A0A2N0LU55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G7|TrEMBL
MAKVTEKCFEATGRNCIICDFSPPRSGDDSVLRNASIDAEFISVAYNPGRAVRVNSAMLA
AAINGQLGKDVVFTLATRDMNKLALQSLMLGAQLLGLENVVVVQGDPFSERDLALIKETG
DTRPTQFIAGVCELNQGVDFRGSQLRSPTAFCIGATVDLGRGIEEEAHLALRKVEAGAEF
IMSQPIFDVIDADRFRQAYQCDSGKELSLPVFFGLQILEKDGVIFSSVPEKIRQELDQGR
PGVEIALELYWKFQESGLHNIYLMPPIRRGGARNYEAAQQFIAATKS
>A0A258MWP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. 35-46-11|TrEMBL
MELSVEFFPPKTPEGEGKLHLVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AVVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
AETGDWFHIDVAAYPECHPQAKSPATDVDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YDLGVTQPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDTASIRAFGEEVVT
DLCDQLLVAGAPGLHFYSLNQADAVLAIADNLSLNK
>A0A2R4NVK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia massiliensis|TrEMBL
MSFYHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIAADYWNSGIRHIVALRGD
LPPESGKPEMYASDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A512DUR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Skermanella aerolata|TrEMBL
MSLAALGLAPDSSTIARTGLRLGTPLPADLAVSFEFFPPKTEKMEQTLWQAVHKLAPLQP
EFVSVTYGAGGSTRERTHATVCRLQKETGLRAAAHLTCVGATRDEIDAIARTYWDSGIRH
IVALRGDPPTGVGTAYEPYPGGYAYAADLVEGLKRVADFEISVAAYPESHPQATSPQHDL
DNLKRKIDAGATRAISQFFFDSEAYLRFVERAAAAGITVPIVPGILPITNFTRAIEFSAS
CGASIPAWMAELFSGLDSDPDTRHLVAATVAVEQCRQLHAEGVKNFHFYTLNRAELTVGI
CHMLGVRPKQPAEATAG
>A0A365USQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora chalcea|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTQAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWIAHPEGVRYAEDLVRLVRDSGDFSVGVAAFPYKHPRSLDVDSDTAHFVR
KCRAGAEFAITQMFFDADEYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFERVADDPEAVRRLGVEQASEMCEKLLDEGVPGIHFITLNRSTATREVWQRLR
AAARV
>A0A1J3E122|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noccaea caerulescens|TrEMBL
PPLLFSHIPFRIWFLSSLRRMKVVDKIKSVIEEGKTAFSFEFFPPKTEEGVENLFERIDR
LVSYGPTFCDITWGAGGTTADLTLDIASEMQNVICVETMMHLTCTNMPVEKIDHALETIR
SNGIQNVLALRGDPPHGQDKFVQVEGGFDCALDLVNHIRSKYGDYFGITVAGYPEAHPDV
IEANGLATPESYQSDLAYLKKKVDAGADLIVTQLFYDTDIFLKFLNDCRQIGINCPIVPG
IMPISNYKGFLRMAGFCKTKIPAELTAALEPIKDNEEAVKAFGIHFATEMCKKILAHGIT
TLHLYTLNVDKSATAILMNLGLIDESKIYRSLPWRRPANVFRTKEDVRPIFWANRPKSYI
SRTKAWNDFPQGRWGDSRSASYGTLSDYQFMRKRSRDKKLQQEWVVPLKSIQDVQEKFKE
LCLGSLKSSPWSELNGLQPETKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGP
GGYVYQKAYLEFFCSKDKLDTLVEKSKAFPCITYMAANKAEKWISNMSQSDVNAVTWGVF
PAKEILQPTTVDPASFKVWKEEAFEIWSRGWANLYPEDDPSRKLLEEVKNSYYLVSLVDN
DYINGDIFSVFA
>A0A7C5YT56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MKAGSHLERVLAAGHFAVTGELGPPQSADAEVILRKARLLKGYVDAVNITDNQTAVVRMS
SIASAVLVLREGLEPVIQMTCRDRNRIAMQSDLLGAYALGIRNLLCLTGDHQSFGNHPTS
KNVFDLDSIQLLQMVAGLRDQKRFLCGEEIKGQEPRFFIGAAANPFADPFDFRPYRLAKK
VAAGADFIQTQLIYDVPRFAEYMERVRRLGLHERVYILAGVGPIKTAGAARYMRDKVPGM
DVPNEIVERMERAVADIPKEDKKARAEAWKREGIQICVDIIQQVRQIPGVAGIHIMSIEW
EEAVPEIVQAAGLYPRPAVE
>A0A0C4USH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria columnaris|TrEMBL
AYGIHLGTEMCKKILAHGIKTVHLYTLNLEKSALAILANLG
>A0A1G6DJH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus henryi|TrEMBL
MSDLLERLKTEILVADGAMGTLLYANGLDNCYESYNLSNPQEVSRIHQAYINAGADIIQT
NTYSAKRHRLKAYGYENNIKEINQAGVKIAREAAGDEIFVLGTVGGSRGLKQCDLTLEEI
IDQTIEQVTYLLDGKLIDGLLFETYYDVEELLAVLEAVRPITDIPIITNLTLLEPGITQN
GQPLVEVLSNLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSFLAVYPNASLLEYSVDG
NSNRFGFSQNAEYFGKSAELLVAEGARIIGGCCGTTPEHIRAVKRVVRGLKPIERKLVTP
LVAEEELIAASKQNETLVDKVKRDITVIAELDPPKTLDITKFVEGIKALDQAGLAAITLA
DNSLARTRICNVSLAAYLKNDLTTPLVLHLACRDYNLIGLQSRLLGMDVLGFDHILAVTG
DPSKMGDFPGATSVYDVTSLKLLSLIKQLNSGKGYSGGSIKKATDFTVAAAFNPNVKNLS
RCGRLLDKKISSGADYFITQPIFNIETIDALSQLTVPYETPFFIGIMPITSYNNAVFLHN
EVPGIQLSEDFLARLEEVKEDKKTCEKLGLEESKRLIDKALEYYNGIYLITPFLRYDLTI
ELANYVNEKREQTDLLLLDKTS
>A0A841GPG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Longimicrobium terrae|TrEMBL
MRDFRQLLADGRPHLFDGAMGTMLYSRGVYINRCYDELSLTQPDLVRDIHRAYVKAGAEI
LETNTYGANRPKLARHGLDGQLYEINAAAAGIARAAAGERVYVAGAMGPLGVRIEPYGPT
AREEARGFFREQAAALADGGVDLFVLETFADLEEIHQAILGVRDASDLPIVAQMVIREDG
TTAFGSDVALLAERLGEWGAEVVGLNCSVGPNTMLNAAERIVGATERPISMQPNAGLPRE
VDGRTMYMASPEYMASYAARLIRKGVRFIGGCCGTTPEHVAAMAGAVRMLAPDAEPRITV
AHSEESATAKEPVPLAERSNWGRKLAAGEFLTTVEIVPPRGSNPEPMLEGVRLLKAAGVD
GVNVPDGPRAQSRMGALATAILLQQRVGMEAVVHYCCRDRNLLGMLSDLLGAQALGLRNM
LLITGDPPKMGPYPDATAVFDIDAIGLTNLVSRLNRGLDPGGNALGEPTSFVVGVGVNPG
AEDFEHEMRRFYWKVEAGAEYAITQPVFDLRQLEKFVERIDRDGLKIPIIAGIWPLVSAR
NAEFLANEVPGVVVPEEVMERMRVASAIGKEAGTDEGTAIAREMLAAAMPMIQGVQVSAP
FGKVPLALRVFEAIPGWSGVVMPEAIPA
>A0A2D5BV88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MAESESRPTFLETLAVRPVVFDGAMGTMLYEQGYFINRAFDEANLVKPDTVRKIHEAHKN
AGAEVIETNTFSANRFLLARYGVDDKVVEINRAGARLAREAAGSDAWVAGAVGPTGEGLG
VMPEYKQRDVRLAYEEQVTALVEEGVDILLLETFQHLREMRIAVEVARGLFKGPLMAQMS
FQEDGHLLDGTAPLRVADLLVAWGADVIGVNCCEGPAIVHDVAAEMVKAGHPVSAMPNAG
RPRRLDQRTLYMATAEYFGVFAKRMLKSGVRVVGGCCGTRPEHVAAVAAAVRMVGGGPAR
VQVSGARSQPATISVEGVTPVPTEEKSQLASKVMRVWQERLGCGARAQAPSGPDDFVVSV
EVNPAPGLSTAKPMKAARMLKAAGIDVINIADGPRAAVRMSNTALALTMQKELDTEVILH
VCCRDRNLLGLQSEILGAHVLGLKNLVVITGDPPKMGDYPKATAVFDLDSIELLKLVEGL
NHGIDPAGKMVGEATSFFLATGAEPGAFDYEREVNRLEMKVKAGAEMVMTQPVYDAAVVE
RFLDSTRSLGVPVLLGICPLVSHRNAEFLHNEVPGMSVPEGIRSRMERAGAGASGVAEGV
AIAREMVAAFSDRVVGCYVMPQLGRYGTAVDVLQPVGYEPGGAP
>A0A7C0U0W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrososphaeria archaeon|TrEMBL
MKADSKLERILESGEFAVTAEIGPPKSADAEVIRRKARTLKGYIDAFNVTDGQTAVVRMA
SWAACLIGKEEGLEPIVQMTCRDRNRIALQMDILGVAALGIKNILCLTGDHVSMGNHPSA
KPVYDLDSIQLIKIVKDMRDEKRFQCGEKITVEPRLYIGAVTNPFAGYPLELDVLRLEKK
VKAGADFIQTQCVYDIEKFEKWMKLVRERKLHEKVHIIAGVTPLKSYRMAKYMKENVPGI
EIPDKILERMRNAPKEKAREEGVEICVEIIERLKEIEGVHGIHVMAIGWENIVPVLVERA
RLLPRPNI
>A0A800MC28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHITDIIGEDKPTISFEFFPPKTEQSSQALFQCIKELEELKPSFVSITYGAGGSTRELTH
ELVIRIKDSTSLTPVPHLTCVNHTEEEIFSILERYAEHEISNVLALRGDPPTGDTPHDRS
AEAFKYASELVGYIQKFKGSGKCKDQRGFGIGVAGFPEGHPETPNRILEMDYLKQKVDSG
ADYICTQLFFDNHDFYDFQERCRLSGINVPIIAGIMPVTSAKGLLRMAELAVGARIPGKL
LKAIDRCNGDTESIKRVGIQYATEQCSDLLNNSADGIHFYTLNRSDATKGIFQSLGLQR
>A0A7C4P5Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MSDFLKTLSNGILIADGAMGTLLHSRGIAFDQCFDALNLSNPGLVADVHRAYIEAGAQII
LTNTFGANRFKLAKHGLEDKVAEINRAGVELARRIVAASFKDVFIAGDVGPLGIRLAPFG
RVQPEEAQVAFAEQISALAEAGADLLVFETISDLYEMQAAVAAARQVCTLPVVASITFTR
DDRTLLGDSPEKVARTLSASGADVIGVNCSGGPAQLLRLLKSMRQAEPKARFWVKPNAGW
PEQVGGRIMYPADPEYFGDYALAFCQAGASVVGGCCGTTPQHIAAMRSALDANPQGCGPQ
YLETSEAVEIAEAWAETEPPSQLAQKLSAGKFVIAVEMDPPRGLSTHKLIAGASLLAEAG
ADVINVADSPMARMRMSAWAVCDVVQRRVGVETTLHFPTRGRNLLRVQGDLLAAHALGIR
NVFVVMGDPTSIGDYPDAMDNYDLVPSGLIKLIKQGFNAGVDHSGASIGQPTNFFVGAAL
NLTPQDRAAEFKNLKRKLKNGADFFLTQPIYEPHVGAEFIQAYEAENGPIGKPILVGILP
LVSVRHANFLHHEVPGVFIPEGTRQRMEAAGEEGAREGIQIAVELIRQIKTWAAGVYIMP
QFNRFDLVAEIIEAVRDDG
>A0A7K1IDL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitriliruptoraceae bacterium ZYF776|TrEMBL
MEERGVARIDELLGGAPTTSFEFFPPKTLAGEQALRQAIKELEPLAPSYVSVTYGAGGST
RQRTHDLVVDLLRTTDLTPMAHLTSVGHRRDELTEILARYRDAGVQNILALRGDPPRGED
GWWELEHAVELVHLAREVGEGRFAVGVAAHPEVHPLATDRGSDRRHLAAKLQAADFGVTQ
FFFRCEDYLAMVEDLAALGCDTPVVPGIMPVTAVGQIVRMAEMSGAAFPDDLAERLYAVE
DDQAAVRAIGVEVATQLCQDLLDAGAPGLHFYTLNRSTATREIHANLALGPVSGGDPEEA
IATD
>A0A7V3GU89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MQFKDIYQQAQAPVLSVELFPPKTEKGWANLEKELAQIMKHQVGFVSVTYGAGGSTRNNT
LELVKYVRETYGVTTVSHFTCVGATKESVIEYVDRAMAAGSENLVALRGDPPKGQIEFTP
TPGGFHYAYQLVAFLKEHYGDRLSLAVAGYPEGHVETRDLATSIEHLKMKVDAGADLVIT
QLFYDNADFFRFRDMAVKAGIDVP
>A0A829I190|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum CFSAN002367|TrEMBL
MAHLTCINSTKDDIDLIIKELKENNIKNILALRGDIPKDKDIIGEYNYAFELIEKIKASN
NFGISGACYPEGHIECKSLDQDIRELKRKVDAGAEHLISQLFFDNNIFYEFLNKTQEKSI
NVPIQAGIMPVVNKKQIERIVKISGATLPKKFMKILDKYEYDKKAMEDAGIAYAVEQIVD
LVSSGVKGIHLYTMNNPYIARKITEVQNQYLIL
>A0A3D1CA36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MKNYPFLQQLSTRPLLSDGAMGTMLHGRGVSFEQCFDELNLTDPDLIADIHKEYVLAGAD
ILQTNTFGANRFKLARHGLEDRVANINQAGVEQARRAIAASQVDRPILVAGDVGPLGVRI
APYGRVQPEQARQAFSEQITALAAAGVDLLMIETISDLYEIVAAIQAAREVRKRKNAPLP
ICASMTFTRDDRTLLGDDPAKVARSLAEAGADVIGVNCSGGPAQLLRLLKAMRQAVPQAF
LLVQPNAGWPEQMGGRIMYPADPEYFGNYALAFCEAGASIVGGCCGTTPQHITAMRVALD
ENPQGCGSLENVLALPDESGEVPETTPETSRLAQRLSQGKFCIAVEMDPPRGISTHKLVA
GASLLAEAGADVINVADSPMARMRMSAWAVCDVVQRQVGVDSTLHFPTRGRNLLRVQGDL
LAAHALGIRNVFVVMGDPTAIGDYPEAMDNYDLVPSGLIKLIKQGFNTGVDHSGTSIGQP
TAFFVGSALNLNPPEPEKEIKNLHRKVKSGADFFLTQPIYRPEEGPVFLEKYEQEYGKLN
KPILAGILPLVSLKHATFLNNEVPGISIPAEILARLEQAGDQAARVGVETTVELVRQIKT
WAQGIYLMPQFHRYDLVAEIIEAVKEK
>A0A7C1JS23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MASFAEALQSKPFVVTAEVGPPKGTDVSRLLHHIDLLKDKVDGLNVTDNQSSVMRISSLA
VCRLILDRGGEPILQLTCRDRNRLGLQSELLSAWVLGVRNVLCLTGDYVSVGDHPQAKPV
FDLDSVQLLQTVELLNNNKDLAGHDMQGATGFLAGAVVTPEADPIEPQLIKFEKKVAAGA
KFFQTQAVYDLEKFKRFMDYARRFPVKVLAGIVLLVSAGMARYMNNNVPGIFVPERLIEE
LAKAEKGKAIEVGIGIAGRMIRQLRQEQICDGVHIMAIGKEERVPDILAAAQ
>A0A7Y3U7L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MKFTDIISSQRPTVSFEFFPPKSDQAASDLYDAADHLRALRPSFITVTYGAGGGTRERTR
KLVMRLNSETGLTTVPHLTCVGATRDELAAIVQEYVDHGIENLLALRGDPPEEHCGPYEP
TPGGFRYANELVAFLKAEFPNLGIGVAGYPEGHPETRDKLLDIENLKRKVDAGADLVITQ
LFFDNRDFYDFVARCELEKIAVPIIAGIMPIQSLAGARKMSGMCGARLPASLLRGIDRAQ
GDKQAVRHVGTHWAAEQCRDLLDHNVAGIHLYTLNKSSATRRIYENLGVKHSDALSQ
>A0A2H3T4W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDDVKGDDERVKMVGVDIVSELIDKIKTIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A7C3LC01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
FLGAAGAPFASRPEFQAIREHKKINAGAQFFQTNLVYDPDGMEVWLNELAKRNILDKVYI
LIGITPLKSLKIAQYMNDQVPGVFIPDSIMQRMENAGDGAAEEGVQITLELIEAIKGKEG
VNGIHLMAVGWESIVPRIVEEAGLLPPDFAPEPEPEKNGRAQLAPA
>A0A3D4TF94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
VNLNHGIYLDDDIRNGGKTDFCIGTAGYPEKHFEAPNLEIDLQRLKDKVDA
>A0A522YJD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
LLQQVVNLNHGTYLEEELKGNNGTTFCIGVAGYPEKHFEAPNMEIDLMHLKKKVDAGSDY
IVTQMFFDNKKFFAFEKACRDAGITVPIIPGLKPITSKKQLSVIPRTFHVDIPSDLSAAV
LKCKDDAAVEIVGAEWLLTQSKELKEASVPVLHYYTLGKPTVIAAVVKAL
>A0A5C4S1K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecochloris vibrioformis|TrEMBL
MLVKDILTSATSPAFSFEFFPPKKDQDWDALFQTISQLIPCNPSYVSVTYGAGGSTRERT
HDLVIRIQKETGLTVVSHLTCIGSEKQEIHDILSTYQEHGIDNVLALRGDLPKGMSSYAE
ATRDFEHAIDLVRFIRKEFPSMGIGVAGFPEGHPQTPNRMTELNYLREKVDAGADYIVTQ
LFFDNRDYFDFVERCELEGITIPIIPGIMPVGTKKGLVRMSELALGARVPAPLLRKVMEA
PDDKAVAEIGIEWAAGQVEELLAADIKGIHFYTLNHAEAAREILVRRCGMAAS
>A0A1I0CJA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas marina|TrEMBL
MESQKKFSPTYSFELFPPQSELGVEKLRVARKKLAQHKPKFFSVTFGAGGSTRERTLETV
LEMQSEGYSVAPHISCIGSTRKNIFSILETYQAAGVQQLVALRGDIPSGMAQAGEFRYAS
ELVKYIREAFGQGFHIEVAAYPECHPQARSYKADLENFQRKIEAGADSAITQYFYNADAY
FYFVESCESMGLSVPIVPGIMPINKFSQLVRFSDACGAEIPRWIRKKLEGYGDDTASIHA
FGLDVVTDMCERLLKEGAPGLHFYTMNSAELTSKIWQRLGI
>A0A0W0IWA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. syringae PD2766|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLELE
NEVKVPAAPHLSCVGDSKEELRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VNFIREETGSHFHIEVAAYPEMHPQARNFEDDLQHFVNKANAGADSAITQYFFNADSYFN
FVERVEKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLQLPR
>A0A2D6W0Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTREEIGELLDVYKENGINRIVALRGDMPSGMGASGELRYAN
ELVEFIRQHSGDHFNLEVAAYPEFHPQARNAEDDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEQMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCQKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A3D5Q3V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp|TrEMBL
SAITQYFFNADSYFYFIDRLEKMNITIPVVPGIMPIVNFTNLVRFSDMCGAEIPRWIRKQ
LEAYGDDSESIRKFGEEVVTRMCEKLLSAGAPGLHFYTLNQAEASLAIWKNLGLDDQKKI
AF
>A0A3L7N036|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MHISDILDQNQPSFSFEFFPPKTEAASEELFATIARLQELQPAFVSVTYGAGGSTRERTH
DLIVRIQKETRLTAVSHLTSVCHNLQELEQIVERYIESGIENILALRGDTPKNLPDYNRN
DDAFQYAEELVRFLKQSSTKAGGRGFGIGVAGFPEGHPEMPNRLKEMDYLKRKVDAGADY
ICTQLFFDNHDFYDFRDRCDLAGIKVPIVAGVMPIATRSGLARMAELALGSRFPAKLLRA
VARSEDDAGTTRVGIHWATEQCRDLLDHQVRGIHFYTLNKSDATRQVFDNLGVSTAKAFQ
ENPLNP
>A0A3A0CJJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRIRERLSTGRPCFSFEFFPPKTDAGLEQLRDSIRALRDLAPSYVSVTYGAGGSTRDRTI
ELVGEIQRHYGFEAMAHLTCVGSTREEIAQVVDRLRSAGVDNILALRGDPPKGESAFTAV
EGGFRHASELAAFIKQAHPGICIGGACYPEGHLECVGPDGRRDLDRDLKNLQQKIDAGAE
FLITQLFFDNNAYFNFVARARSAGIGVPIIPGIMPITNVDQVRRFTQMCGASIPESLLRE
LDRLKDNEDAVLSQGVAYAAAQCFDLMNRGAPGIHFYTLNKSAATRTILTALRTIWPPAA
RPA
>A0A1Y5HV05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleispira antarctica|TrEMBL
IRVFNKIAQGCNFFISQGVYDVNASKNFLSDYYYYGLENNIPLVPILFTLTPCGSQKTLE
FMKWLGISIPKWLENELLHSKDILQKSVEVSEQNYLELKRFADEKGIPIGCNIESVAIRK
VEVEASIELLRRVSQ
>A0A656Y7D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus kefiranofaciens subsp. kefiranofaciens DSM 5016 = JCM 6985|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSKEAMRDAGIAFAVDQIIDLVSEG
VDGIHLYTMNHADIAERIWNATKSVFDAANARTWTTIA
>A0A1F3BZR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeromyxobacter sp. RBG_16_69_14|TrEMBL
MKVADILRFARERGEPVFSFEFFPPKTDDGVRQLFETVEALRPLGPAFVSVTYGAGGSTR
QRTVELVTKLKRETEVEAVAHVTCAGASRQELGHVLDEIAAAGVQNVLALRGDPPRGQTA
FEPSPEGFRYASELVAFIRGEKRWSFCIGAAAYPEGHVETRDLARDLANLKTKVEAGADF
LVTQLFFSNAHYFRFVERARAAGIAVPILPGIMPFTNVDQIERFTAMCGAQIPPALRAAM
EVRRVDSEGALQLGVAYASLQCADLLRRGAPGVHFYTLNRSPSTRAIVAALRSSQPWRDG
>A0A434EHK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M6A.T.Ca.TU.002.02.2.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQIRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDQIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A523NCI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MHIRDIFGRDSMTLSFEFFPPRTDQGWEALFRRISDFEALGPSFVSVTYGAGGSTRQQTH
DLVMRLKDGTDLDPVPHLTCVCHTEQEVGHILEQYARRGISNIMALHGDPPASVPDYNRS
DDAFRYAIDLVKFTRRFGQDGGHTDPRGFGIGVAGFPEGHPDTPNRLVEMDHLKAKVDAG
ADYVCTQMFFDNQMYYDWCERCELAGIRVPLVAGLMPITSARTLHRMAELSGGTRFPAPL
LKLIERCGDDAEAVKRVGMHWATEQCRDLIDHGVSGIHFYTLNQSDATKHIYQTLGAKDS
ASLR
>A0A354TC23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHIADILAARHPSFSFVFFPPKTTEAAGKLFESIAQLEPYAPAFVSVTYGAGGSTREMTH
DLVLRLKTTTSLDPIPHLTCVCHQEAEVVDILERYAAAGVGNILALGGDPPRDLKSYNKA
EDAFQHAADLVAFIKKFNDSGAHPDKRGFGIGVAGFPEGHPTTPNRVLEMDHLKAKVDAG
ADYICTQLFFDNHDFFDFRERCQLAGIKIPIIAGIMPITSASGMRRMAELAAGARYPAKL
LRAIQRCGNDEDAVQKVGIHYATEQCHDLLDHGVDGIHFYTLNKSHATREIYASLGIRDS
AAVRPQS
>A0A0M0JFE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chrysochromulina tobinii|TrEMBL
MALTGGTLRSLSLEIFTPRSTKGIDDLLASGGRLAAYAALGPSLVSVNGPGLQILEHVRA
THSIRPQMQISRPEVTLDSIESMLDSAMGVGVRDVLILGGQPGQRTAPGAFSSVLDLVRC
IKERCGERMRVSVCGYPRGACGELGEYDADLQALALQVAAGAELVVSLPCFDAETHSEFA
ADARAAGVRCPIVPGLLPVGSVAADFRRICRAIAVEVPKWLDDQLLATSTSELLASLSDT
LLIKQLRQLRLQGAEPPHVYTLNAAEILRPLASAGFGPLKHRI
>D7GEV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium freudenreichii subsp. shermanii (strain ATCC 9614 / DSM 4902 / CIP 103027 / NCIMB 8099 / CIRM-BIA1)|TrEMBL
MLDNYRPADLAPARRSNTDTTQTIAELLARAERPTFSVEFFPPKTDEGARVLHEAIEKLE
PWNPDFVSVTYGANGSLRDRTLAAVRDMVASTKLRVVGHLTCTGQSVDELKSVIDAYGDL
GVHHILAVRGDMPGGPRQPWEPHPQGLKNATELVELVKSRGDYCVGVGAFPDIHPGSTPE
QDVRVLHDKQDAGAEFAITQLFFRPSAYYDLIDRMRADGCTLPVIAGMMPVTAISQLDKF
AELSGVPLPASVTERLMAVANDPLAVRATGAQICAELASDLLERGAPGLQFFTRNRSAAT
REILAILLARRPW
>A0A524FZE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAEKKVYSRLGEALAKGDFVLTGELEPEKTCDLSHLVEEAKEMAPYVVAANVTDSPLGIV
TINSLAASYIVQRDAGLECIWQLTVRDVNKLGIAGMIMGAQALGIHNVLSLTGDHPNMGD
MPESKPVFDLDSATLVKLVREMVDTGAINGKEIEHPPKLHVGAAANPNSDPMEAEVLKIG
RKAVAGAEFIQTQVVYDLDRTIEFLREINKYKVPVLLGLFPMKSYAIAKGFDMFVPGVDV
PKDILAKWKGIKTDVTDKKAQKEAYDQANYEFFKPFVTELKAKKLLAGIHCMAVHYPRIF
PKLVEVIKG
>A0A6G7A8U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. BIOMIG1BAC|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASCNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKVPSAPHLSCVGDSKDDLRGLLQQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVDRVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQAISEMCERLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A7K4H061|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MPQRPAYSNLVKTIREGKFVFTGELEPEKDFDLKHVLHSAEEMKKTGKIVAANVTDGPQG
DAYTCSMVPCYLVQEKVGLETIWQMTVRDRNRIALFGDLLGGAILGLKNLLALTGDHSAL
GDHSNARAVYDLDSTQLIELVSKMVDEGTDLEGNEIEGGKPQINVGCAANPNSNPREPEI
LKVGRKVEVGVDFIQTQTSFDVDDAKEFLKELEKYNIPVLLGLFPIKNYGIAWYFNEYIP
GVSVPNDFLNALKATKKIKDKKEKYAAIDKINLEFFEPFIKEIKKTTKAAGIHCMAVHYE
RLFGPLLKDF
>A0A8H9CM87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. OF001|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLTVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLATYKDAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGEHFHIEVAAYPEVHPQARSFEDDLRNFVRKAQAGADSAITQYFFNADCYFY
FVERVRKLGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDLASIQAFG
EQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7K4H149|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAEKKVYSKLGEMLANGEFILTGELEPEKTCDLSHTIQEAKEIAPYVVAANVTDSPLGIV
TINSMAASHIIQKEAGLEVIWQLTVRDVNKLGIAGMIMGGHALGLRNVLSLTGDHTALGD
MPESKPVFDLDSATLIRLVKEMVDKGTINGHEIEHPPTFHVGAAANPNSDPMGAEILKIG
RKAEVGCEFIQTQVVYDLDRTIEFLSEIKKYNVPVLLGIFPMKSYAMAKGFDTFVPGVDV
PKDILAKWKNIKTEFKHDKKEQKRLYDQANYEFFKPFISELKKKGLLSGVHCMAVHYPRI
FPKLMEVIKA
>A0A379FA43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus vulgaris|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTEEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASREELQHIAQDYWQSGIRHIVALRGD
LPDNTQKPEMYATDLVHLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGADRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMNKMFD
GLDNDPETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPELVRA
>A0A4Q3QDT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MGLPLSFEFFPTKTPEGAVKLRAVRQQLYVRKPEFCSVTYGAGGSTHDGTFGAVREILQE
GCDAASHFSCIGATRATVRDQLAELKAMGVKRLVALRGDLPSGYGIGGEFHYASDLVAFI
RAETGRDFHIEVACYPEVHPQARSPEADLQAYAAKVRAGADSAITQYFFSAEAYFRFVDE
SRKLGLDIPIVPGVMPITSSNQLMRFSDACGAEIPRWIRLRLQAYGDDLDSIRAFGLDVV
AGLCERLRAGGAPALHFYTMNQSQATLGVLERLG
>A0A1B5L7K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ustilaginoidea virens|TrEMBL
MDKITDKIAALPADRDYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
AAKSLELAELCQCQLGLTTCLHLTCTNMSKHLIDKALDDAKVIGIRNILALRGDPPRKEE
YRDANGHGPEDDGSADFTWAIDLVKYIRKRHGDYFCIGVASYPEGHSDESHPQGQSLEKD
LPYLVDKVRAGADFIMTQLFFDRTAYDHFEKTLREHPSGALETIPIIPGLMPIQSYQMIK
RTTKLSHARIPPAIMSRLDAVKGDDEKVKLVGVDIISELIEQIRTIKNRSPGRKGFHFYT
LNLEKAVSLITERSGLIPDAADQDEAVTDDYPRAPLALRVNGTARTSRTSSHSRASRRRS
SVGSDPYNRVIVGGRPATHPEWEATGQEAGVPAEGINSRANTLAISEGEGVLGREATWDD
FPNGRFGDSRSPAYGEIDGYGVSLHVSITRAVTLWGHPKTREDVDDVFVRHIKGEIEAIP
WSEEGLSAESSTIQPRLVEMNTKGWLTVASQPAVNGIPSSDRTFGWGPENGFVFQKAFAE
FFLPSADWRALAGKLAGPDCSGSVCFYAANARGDFASSDATGGASARTVAASTNAVTWGV
FPGKEIITPTIIEEVSFKAWSEEAFGLWGEWAKVYARGSESEAVLSAIRSDYWLVNIIHH
DYMDKDALWRLLLG
>A0A4Q3PFL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
ASIRAFGTDVVGQMCQDLLDEGVPGLHFYTLNQSDAIMGIYRQLDLSHS
>A0A5A7ZKU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFHALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A0E3YWN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium IMCC26134|TrEMBL
MPARADRPISALFSENRPLRSLEFFPPKDDAGVAALRATAVMLQRIPWDFVSVTYGAGGT
TRDRTAQVSTFLKDELGFTVMPHLTCVGHNRAELIELADRLHADGFRNIMTLRGDAPKGA
STFTPAPDGLRYANELVTLLKNRHPDFCLGVGGYPEKHPEAVSLDADLDALKRKVDAGAA
FVTTQLFFDNAIYHRFVEKCRAAGITVPIVPGIMPVLSFKQIQRIATLSGSVLPATLMRR
LEVASEDGDVVEFIGVDWALDQIRDLLAHGAPGYHLYILNRARSALALAAGLAA
>A0A5D4GVK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium microcysteis|TrEMBL
MTTRPPQPDENPHGPDLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYER
AKVFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPVYQISCRDRNRIAIQGDVLGA
AAMGVANVLCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDEQKFLSGRKLTTPPAV
FLGAAINPFAPPVEFRPLRLAKKIAAGAQFVQSQYCFDVPMFRDYMKRVRDLGLTDKCFI
LVGVGPLASAKTARWIRSNVPGIHIPDAVIARLEGAADQKKEGKQLAIDIINEVKEIEGV
SGIHVMAYRQEEYVAEIVHESGVLKGRRPWKREPRADDALVAERLEHILHDTPTENPQQI
VSDVAH
>A0A7W2BS22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSIDINPKDLGGPLDPLPGHASRGRLERILRRGEFAVTAELNPPDSADPQDVYDRAAIFE
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDEAKFLSGRKLTSPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFRDYMAKVRDLGLHEKCFILVGVG
PLASAKTARWIRSNVPGIHIPDSVIARLEGAKDQKKEGKQLCIDIINEVKEIEGVAGIHV
MAYRQEEYVAEIVHESGVLKGRRPWKHEANPTDTVVAERLEEIRQGKEENQQQLADIAAH
KPH
>A0A662B2T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MSLFTPGRRWQPPFFPFKKEPFGKRVLRSIERWTKGPMFGCRMCGNCLLQETAFICPMEC
PKGMRNGPCGGSTPEKCYVDETRPCIWYKIYERSFKMGREHMLLEVLPPLDWDKVGTETW
GDVARSVRKYGTGSFIRKRFSGNKEKKQQSWEAVFQPVRQPHWWAGDSLYHAPAYDLPFS
RLEKELKSGNFVITAEVSPPLSTATGKLKRDITMVKELVAAVNFTDSASASPRMSSMACS
KIAAELGADPVLQIAARDKTRSGLQSDIMGANVMGVHNVLCITGDNARIGPTPTSNTNIL
DMDAVQMLWILRRMRDEGIYLDGRKMKSPPRLFLGAAASPFASEQRFQALREEKKINAGA
QFFQTNLIYDPEGLDLWLEALDKRNILDKVYILAGVTPIRSKRMAQYLHHNIPGVRVPQP
ILDRFDEAKEDDYEELGVEIALEIIEKIKDKQGINGLHLMSVGWEAIVPRILSDAGLSQF
QGNQ
>A0A7V2SLX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MTILSQNAFNVSRDPGNFTVSFEAFPPMSPKGQEKLLEVAHDLEEFAPEFFSVTYGAGGG
TQQRTLDTLSDIAEKTSHNLAGHLTCVGATRQQTNAVAEKYRSMGVNRIVALRGDAPEGQ
DHYQPHPGGYKNAADLVAGLKELGGFDISVGAYPESHPDSPSRAADLDNLQAKFAAGADR
AITQFFFDNHVFYDFMDEAEDHGITGPIVPGILLIHDFWKVKRFAKLCQTDVPDWLEARF
AGLEDDPAAQQLVSVSIAVEQVLDMAANGVRHFHFYTMNKSDLAVAVCRSLGLKPSKELR
SVA
>H0PRP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azoarcus sp. KH32C|TrEMBL
MAKPELSIEFFPPQTPEGAQKLRDTCRKLATLKPSFFSVTYGAGGSTRERTFATVREIAA
DGFEAAPHLSCIGSTRASIREILAEYAAAGIRRIVALRGDLPSGVGDPGEFRYANELVEF
IRNETGDRFHLEVAAYPEWHPQAKSPKDDLLAFKRKADAGANSAITQYFYNFDAYAHFVE
SVRAMGVELPIVPGIMPIVSFSKLARFSDACGAELPRWMRKKFEAFGDDAESIRAFGLDV
VTELCERLIAAGAPGLHFYSMNQAGLTTAICERLKLGC
>A0A3S8URM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas entomophila|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLAEYQAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFENDLANFVHKVKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A4Y1N2S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas mucosa|TrEMBL
MNHVATPGAGASGASPGHDPGIHPGANPLGRWLTGPRFGALPAPAALPAPALSFEFFPPR
TEALENQLWACIRRLEPLAPRFVSVTYGAGGTTQARTHATVSRLVRETALTPAAHLTCVG
ASCGEVDDVARQYWDAGVRHIVALRGDPPAGAPDYVPHPQGYAYAADLVEGLRRVAPFEI
SVAAYPETHPSARSAEADLDNLKRKIDAGATRAITQYFFDTETFLRFIDRALAAGISVPI
VPGIMPVSNFNQMRNFSARIGASVPDWMAALFEGLDDDAETRRMVAAVVAAEQVRLLQAN
GVDEFHFYTLNRPDLTYAIAHILGVRPSRPADPASESGVEEEGKAEAASRQAGQAGA
>A0A2S7YZT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. S13053-19|TrEMBL
MTLREKHQQGKFTITVELDPPKSSSAEKVFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDAPTSFYIGATGNPGAPDLEIERQKLAAKIQNGA
HFVQTQPIYDLEQAKRYIDTMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A2N2SXI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-18|TrEMBL
MTSIVHWPVSIEFFPPKTPEGVEKLRTVRQQLYTLNPEFCSVTFGAGGSTQEGTFSTVRE
ILSEGVSAASHFSCIGATRERVREQLGTLQAMGVKRLVALRGDLPSGYGTGGEFHYASDL
VAFIRTEMGGDFHIEVAAYPETHPQAKSPESDLQAFATKVQAGANSAITQYFYNSDAYFR
FVEDADALGVQVPVVPGIMPIASSSQLMRFSDACGAEIPRWIRLRLQGFGDDTTSIKAFG
LDVVTDLCEQLRAGGAPGLHFYSMNQSAATLEICNRLGL
>A0A0M8VAK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL WC-3618|TrEMBL
MLGRVRYEVLPAKATEDKVLAHVPRDIVVTVTASPVKGLEPTLDLTGRLAAHGYRVVPHV
PARLLRDDAHLKDVVDRLRETGVDDVFVPAGDADPPAGSYEGALPVLRRLGELGSPFTHI
GVTGYPESHPLIHDDVTIQAMWDKREHATYIVSNLCFDARVLGEWVGRVRRRDVALPVYV
GVAGPVQRAKLLSMATKIGVGESTRFLTRHPLWFLRFAAPGGYSPERLLTAAEGALTAPG
AGVAGLHLFTFNQVEETERWRQGLLERVGG
>A0A3C1WPJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHIANAKSTLISFEILPPLKGAGIQSIYNTLDPLMDFKPPFINVTYHRSEFIFKKT
AEGLFEKKIVRKRPGTAGICTAIHTKYKVDTVPHLICGGFSVDETEDLLIELNFLGINNV
LLLRGDKMKSEEVFSSEKNGHQNAIDLVHQTVRMNKGIYLEEDLNNAVPTDFCIGVAGYP
EKHYEAANMESDLNYLKAKVDAGANYIVTQMFFDNKKFFQFVKLCREKGITVPIIPGLKP
ITNKKQIANLPRIFNVDIPSELLIEFDKCNSDEDVKQVGIDWCINQCRELMKEKIPVIHF
YTMSNSGPVKKIVENIYS
>A0A349QEB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MMNHNTERSGRRSQDADKLKISFEFFPPKSEKMEENLWASVERLAPLSPSFISVTYGAGG
STRERTHDIVARMVEETKVKPAAHLTCVGATKQEVNDVIRSYADCGVNHIVALRGDPVDG
VGSRYEPHTGGYVNAADLVSGIREIGDFEVTVSAYPEKHPESPDFAMDIEMLRQKVDAGA
TRAITQFFFDNDLYEAYVERVRRAGIFIPIVPGILPIHNFKQMANFASRTGASVPQWLAN
RFEGLDDDPETHRLVAAAIAAEQVQDLLERGIDDFHFYTMNRANLSYAICHLLGLRPDGA
>A0A1D8FZ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rubrolavendulae|TrEMBL
MALGTPSTRTDRARTVRDLLANGTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVT
YGAGGSTRTGTVRATEQIAADTTLTPVAHLTAVGHSVAELRNMVGQFADVGIRNILALRG
DPPGDPMAEWVAHPQGLDYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDTDVRHFVDK
CRAGADYAITQMFFEPESYLRLRDRVAAAGCDTPIIPEVMPVTAVRQLDRLPQLSNAHFP
AAVRDRILAVKDDATAVRSLGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQQS
>A0A2N6B2L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MLVQTPNKARLDEDTRGVSVSFEFFPPHDDKMDAALWTAIRELEPLSPAFVSVTYGAGGS
TRERTHATVERLLRETTLKPAAHLTCVAATRAEIDEVISGYKEIGVRHIVALRGDPPGGI
GEAYTPFPGGYENAADLVGGIRRIGDFEVSVSAYPEKHPESPDIETDFDMLKAKIDAGAT
RAITQFFFDNRVYYDYVEAARKRGITIPIVPGILPVLNFKSASGFATKCGAGIPPALARA
FEGLDNDAETRRLVAAAIMAEQVSDLHDHGVRDFHFYTMNRARFVYTICHLLGLRPGA
>A0A432KGK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHINNAKNTVFSFEILPPLKGQNIKALFENIEPLMEFKPPFIDVTYHREEYVYRDK
GNGLLEKRTTRKRPGTVGICAAIKNRFDIDTVPHIICGGFSKEETENALIDLDFLGIDSV
LVLRGDPIKSENKFVPDPNGHAYAIDLMEQVVNMNQGKYIDEELQSATPTDFCIGVAGYP
EKHFEAPSMKSDLKILKQKVEKGAEYVVTQMFFDNQKYFDFVKLCRAEGINVPIIPGLKP
ITSLKQMSALPRTFYLDLPDDLVDELEKCKDNAAAKEVGIEWCIQQSKELIEFGAPCLHY
YSMGKSDPIYRIAEGVF
>A0A2P5I1J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diaporthe helianthi|TrEMBL
MHIKEMVADAEKTAAPSFSFEYFPPKTLTGVQNLYDRMERMYNFGPKFIDITWGAGGRIA
ELTCEMVSQAQAYFGLETCMHLTCTDMGLEKINDALRKAYKAGCTNILALRGDPPRDKEK
WEAADDGFRYAKDLVVHIRKTYHDHFDIGVAGYPEGCDDNKNEELLLDHLKEKVDAGATF
IVTQMFYDVDNFLRWVDKVRGRGITIPIIPGIMPIATYSSFLRRVNHMKCKVPQEFMDAL
EPVKNDDSAAREVGKTLVANMCRKILAAGIPHLHFYTMNLAQATRMVLEELDWMPSERSP
VKQALPWKQSLALGRRDEDVRPIFWRNRNKSYISRTMDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEENRKKWGEPKSVKDVATIFLKYLNTELDQLPWSESPLTTEADTIKEDLIE
LNKRGLVTINSQPAVNGVKSTHPVYGWGPPNGFVYQKAYIEMFVSPDVYPELISRIHRHP
DLTYYAVTKAGNLATNTPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGTDW
ANCFEAGTPSRILLDRMMRDWYLVNIVNNDFHQPRTIFEVMKGLQVKDIDVEIQSDGHTA
N
>A0A537KKY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MTVIEHINQAKDTVISFEILPPLKGKGISAIYDHLDPLMEFKPAFINVTYHRSETMFKKK
PDGTFEKVEVRKRPGTVAICAAIMNHYKVDAVPHLICGGFSKNETENALIDLNFLGVDNV
LILRGDAPSNETFFEPEPDGHRYAIDLMKQVANMNNGIYLEDDLKGVVKTKFCMGVAGYP
EKHFEAPNMETDLRFLKAKVDSGAEYIITQMFFDNQRYFDFVKRCREIGITVPIIPGLKP
ITTKKQLAVIPRTFYVDIPSELANEIIKCKMDEEVAQVGTEWLIQQSKELKNFGVPVLHY
YTLGKASVIAKVVKAI
>A0A420ZJT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacinutrix venerupis|TrEMBL
MKVTEHIKNAKGKTLFSFEIIPPKKGKSIQDLYDNIDPLMEFNPPFIDVTTSREEYIYIE
KQGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFSKEETEYLLVDCHYLGINNV
MALRGDAMSHQKYFEACKGGHQYASQLVSQIQNLNCGNYLHDVVEVDDTSDFCIGVAGYP
EKHIEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVDAAKKAGIHVPIIPGIKP
IAIKKHLQLLPQVFKIDLPQDLITSIEQCDTNKQVRQVGIEWAIQQSKELQAAGVPVLHY
YSMGKSDNVKAIAEAVF
>A0A351C6Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVVDLLKTDGAPSISYEIVPPRRGGSIQDILEIVEGLKEYDPPFVDVTSHSAQVYYEEQ
QDGSWRRHIKRKRPGTLGLCAAIQGKFGIQTVPHLLCKGFTREESEDALIELNYLGIQNV
MALRGDDSG
>A0A351C3K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVVDHLTKATKPLISFEILPLPRGGDINVLFNSIEKLMKYEPPFIDVTSHSSQVYYVET
PKGISKKVMRKRPGTIGISVAIKNKFNIDTVPHILCNGFTKEETEDALIELNYLGIENIL
AIRGDELSFKKPVPEGRTCNIYSTELVKQIVNMNAGHYLEEDLLDASPTNFCIGISGYPE
KHFEAPNLNSDIKIAKEKIDTGAHYIVTQMFFRNKYYLDYVDKCRAAGINVPIIPGLKIL
TTKNHLNSIPKNFFVEIPDELSNEIQEAKPEHVIDIGVEWAFKQSEELLNKGAPSLHFYI
MQSSKPIEKLMKKLNI
>A0A3M1UAJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MRVIEHLSTCKNPTVSIEIIPPKRGGSIQKLKQAIESILPFDPPFIDVTSHAAEAVWEEM
PDGSYKRKVKRKSPGTFGLCAMIKYKYNLEPVPHLLCSGFTREETEDALIELNYLGIENV
LAIRGDKQNPRPIPQDRSINNFAVDLVQQIANMNRGIYIDDLIDADKSNFCIGVACYPEK
HFESPNLTYDLNILKQKVEAGAHYAVSQMFFDSQKFIDFVQAARQAGIDIPIVPGMKILT
SKRQLNVLPSIFHVDIPEELTDRMLATKTRKEAIEVGVEWAFRQSIQLLEAGFPYLHFYI
MQNTTPFVKLMDKLRMKV
>A0A4Q3JG50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
RTLRMVSRIKSDTGVDAAAHLTCVGATRDEVDAVVRGYREAGISRIVALRGDPPEGIGQP
FTPHPQGYQNAADLVAGIRGIGDFDISVAAYPERHPQSPDWDTDIENLKRKLGAGAARAI
TQMFFDNDDYFRFVDRARKAGITAPIVPGIQPIHSFKQISGFAARCGASVPDWLAQRFEG
LEEDPETHALVASAVAAEQVLELVDHGITEFHFYTLNRSNLVLALARLLGVRPS
>A0A1D8S810|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio mimicus|TrEMBL
MGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKNLKPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQNIVALRGDI
PPGGGKPDMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPNWMVKQFEG
LEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A243C0T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar yosoo|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGSLLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEERSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>M0MQ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halococcus saccharolyticus DSM 5350|TrEMBL
MSVARSAAASDGATDLLTDLRFELMPFDSFEGQMDHLPDGATIAITTSPQLGLDATIEWA
EKAAEQGFEVSPHIAARYVRDEEHLAEIARRLTDAGITDIFVPGGDREDPIGEFESAYDL
LTTLDELDYAFEEVGITGYPEGHEFLDEATLAEAMEKKAPYATYIVTQLCYDPDAVVAWI
EEIREQGIDLPVEVGIPGVMKYQRLLNISQKVGVGDSVRFLKKTTGIVGFVRQLVGSRGK
YTPDDLIDGLAPYAGDSHYDIRGLHLYTFNQTSDTESWRYGRLEE
>A0A1E7N4C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora aureofaciens|TrEMBL
MALGIASTRPDRALTVRELLAAGKRSFSFEFMPPRTEVGEQKLWDAIRRLEPLDPNFVCM
TYGAGGSSRERTVNMVGRIATETTLTPVAHLTAVDHSIAELRNIIGQYADQGVRNVLAVR
GDPPGDPMGEWVRHPEGVTYAYELVELIKGIGDFCVGVAASPNMHPRSTDWDEDIRHFTA
KIRSGADYAITQMFFEVDDYLRFRDRVTAAGCETPIIPEIMPVTNAKQLERFPQLSGSAF
PANLEARLRAVVDDPAALRAIGMEHATAMAERLLAEGAPGLHFITLNHSTATLEIYQNLG
LHQRP
>A0A7M2RKG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia liquoris|TrEMBL
MKLTDIMKKRTMFSFEVFPPKTDEAMVKLGKTLEHLYEFKPDYISCTYGAGGSNVGRNLE
VCKKIKEADNDTIPVTHFTCVGNTKEGVKEQLQNYLDNGINHMLALRGDLPYGWTGTNGD
FAYATDLLAYVRKEFGDQFEIAVSGSPEGHITCGTLEADIAHLKQKQDEGADYIMTQLTY
DMEQFKYWFDTIRKAGITLPVDVGVMPVVNKDSVINMCLSRNGSAIPRKLAEIISHHWFD
KDPDGNPLPEVKEAFREEGINYTVNQLHEYMAIGVDGIHLYAMNTWKNSTEILNRAGIRT
LVN
>A0A7D6IIV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium IMCC25003|TrEMBL
MRSVKSDGTKALTYSFEFFPPKDVEGEERLWAAMSQLESIAPDFISVTYGAGGSTRDRTI
RITSEITARTHIPTVAHLTCVGSTRDELIDILSKYRDAGIKSILALRGDPTGGPRAPWSA
TEGGLNHADELVTLAAEFGGFTIGVAAFPDGHPSSNGDLDKDVQVLLEKEKRGATFATTQ
FFFEADRWKNLVDKLAAQGSSLPIIPGILPVTNVKQLNRMAELSGVPIPASISDAFAKVE
SNPEDVRKLGVEIATKLCEDLLEAGAPGLHFYTMNTSSATREIYSQIKDER
>A0A259ULB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa silvacetica DSM 10669|TrEMBL
MSEAVAIDKQAVLKTDSKLEKLYSLGHFVVTGELGPPQHSEGHELEHHAAELKDIVDGFN
LTDNQTAIVRLSSIAAGVHVLKGGGVPIIQMTCRDRNRIAMQSDLLGAYSLGIRDVLCLS
GDHQSFGNHPTCKNVYDVDSVQLIAMVKKMRDEKKLLSDAAIKTNEPRFFIGAVENPFGD
PFEFRAIRLEKKVNAGADFIQTQAIFDIEKFARFMEMVVARGIHERTKITAGILPVRSVK
ALQYMKKDVAGMEIPDSLIERMKNAEDPKKEGIQVAIELCNQLKKIPGVAGIHIMPVGWE
AALPEIVKGAGFLPRPKV
>A0A1E2VCN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terasakiispira papahanaumokuakeensis|TrEMBL
MTQTTPISFEFFPPKTDAGRAKLVGVRDTLATLAPEFFSVTYGAGGSTQEGTLNTVLTLR
ESGIDAAPHLSCVGATKAELSALLNDYRDQGIRRLVALRGDLPSGMGMGGELRYANELVE
FIRAEHGDHFSIEVAAYPEAHPQANSFETDLNNFIRKANAGANSAITQYFFNADAYFYFV
DRVRAAGVEIPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAFGDDQDSIRAFGED
VITRLCQQLTEGGAPGLHFYTLNQADSCANIVKRLR
>A0A2S9J8Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium haloxyli|TrEMBL
MKIIDHIKNANGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYLYKQ
HTSGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDPDFVPTPGGHAYATELLQQVIDMNSGKYLHEDIESTAKTDFCIGVAGY
PEKHFESPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PMTTKRQLIMLPKIFHLDIPEELSEAVETCKTNAEVRQVGEEWLVEQCKELIKFEAPVLH
FYTMSNPGPTKKIVERLA
>A0A1X7IV86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus rhodochrous J3|TrEMBL
MGELLGRQVIGAGRQDETSRSMGDGTSAAGEPEAPRPAYPHTRVVAGSDRPGGATYAGPV
TSDFVRATEDDGISRTPSIVDRLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERLG
PAFVSMTYGAGGSTRDRTVRITGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGIT
NILALRGDPPGNPLGEWEKHPEGLEYADELVRLVRDLGDFHVGVASFPEGHHRSPDLDHD
TRYLVQKLRAGAEYSITQMFFDVEHYLRLRDRVVACDAEQGLKPIIPEIMPITSLRSARR
SLELSGSHLPPVLEERLRRAAGDGPEENRAAVREVGIEVATEMCERLISEGAPCLHFITL
NFARATGEVLDRLGYELEAPAAVQPA
>A0A4Q7YMG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fluviicoccus keumensis|TrEMBL
MSRNIPISFEFFPPKTPEGAEKLLTVHQQLSALNPQYFSVTYGAGGSTRERTLSTVFDLQ
AIGPAPIAPHLSCIGDSKAALAGLLDGYKAKGINRLVALRGDLPSGQMTLGELPYARDLV
AFVREHSGDHFHIEVAAYPEMHPQADSYEADLRNFIAKAQAGADSAITQFFFNADAYWHF
MDRLARAGVTIPVIPGIMPITNASNLIRFSDSCGADIPRWLRKQLLAYGDDSASIKALGE
TVVARLIEELIQGGAPAFHFYTMNQSEATTRLVKLSGLA
>A0A351NTM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MPRSMVEEKQALVDMMLKTTLEVTPGGAAKVADFVPILRPGCTVYVTFLPGSDFADTLAT
VRRLKSDGYNPVPHFAARSIVSSAILEENLAALQHEGVSEGLLIGGGVDKPLGEFEASID
VLHTGLFEKYNFTKLGLAGHPEGSPDISDADCSLAIEQKNHYAKNSSMELYLATQFIFEA
EPLLAWEKRIRQQGNKLPVHVGIPGLATIKTLLRHAQHCGVGPSMRFLTRSPMNMLRLSL
KDSFLGSYVNAPASEPSELVRDLVVGMDNDADCLIKQFHLYPLGGLAKSAQWMYKIQDGH
FQLTGNGFKTL
>A0A4S4ZZF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp|TrEMBL
MRNTDRPAVLRLLTHARYEILPTATIEAKVLDAVPTSVPLTVTASPSMGLERTIATAERL
AAQGYTVVPHLAARMVSGRSELEELVGRLQAAGVTNVFVPGGDAEAVGDYVDALSMLEDL
TEIGRPFAQVGVTGYPESHPMIHDDLTVQSMWDKRRHATYIVSNLTFDPAVIKDWIHRLR
LRGVTLPVLLGIPGPVDRAKLLGMATKIGVGDSTRFLAKQKGLMARLVAPGGFTGESFLS
KCAATVGEAEANVTGLHLYTFNQVAETEAWRQDWLSRLQG
>A0A351Q6U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
KVFILPGVGPLASAKSAEWIRNNVAGVHIPDAIIKRLAGAQDQKQEGVNICIDMINEIRE
IEGASGVHIMAYRQEERIAEIVEKTKVLGNRTPWHPQS
>A0A1C3F740|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp. BG|TrEMBL
MKNAVDLKSKFATGDFIYTTELGAIDGTLLEDRLTLAQDYEGLDAINVHDCPNANLRMNS
VMAASILKQQLGIETIPHFTCRDRSLLGTQADLLGAHALGIRSILATTGDAPNHGPYKGS
KGVYNYNSFELIKLITNLNSGKDANEVEIKGCTDFTIAATATPGTTNLTVEIERMKKKIE
MGADFFQTQPIYDVAKTREFLAEAKMLGKPILLGVMPLINLKLVKFINNKMAGVTVPDEI
IKQMEEGKSGLEIAFEFVAEFSRDIQGIHIYGMGDVQMTNKIIAFAKNLR
>A0A6N8IHN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonibacter urolithinfaciens|TrEMBL
MRSVSDIYAAARAAGRQPVSFEIFPPKGDLTLETAHEVAAELADLLPDFVSVTYSAGGSG
NRQATADVAAMIHDDFDIPTVAHLTCLGATEESISRAIDDLKRKGIASVLALRGDRTADA
SEAEGPFRFAKDLVMRLADEGFCVGAAAYPEGHIECTDFRASVAHLKQKQDAGACFFVTQ
LFFDNAYFYRFREAADAAGIAVPIACGVMPFLGKAQIQRMVFMCGASLPSPIIKLLAKYE
DDAAALRAAGIEYACAQLVDLQEHGADGLHVYTMNQPDIARACAGALRATWRPAGEAAVR
GAGEPVGGRA
>A0A3N5V804|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPGFTPGRRWQPAYSPFKKANFGDRALQVLEYSVKGPLFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGSTSEHCYVDETRPCIGYKIYERAFQLGRQELLLEILPPLDWEKVGQDTW
RDVFRSVAKTGLKKVVRGFLSGSVETRKGTWDEVFRPVRQPDWWQGDSLYHPPAYTEPAS
ELERRLVAGEFVVTSEITPPLSSKTDKLIHHIEATKPYVAALNFTDNASATPRMTSWACG
QIAVEHGAEPVLQISARNRSRSNLQSEVIGAAALGIRNILCVTGDSAKLSPSPREKMEIN
DLDAIQMLWILRRMRDEGKYLDGRAIKYPPKFFLGAAASPFASEPRFQALREQKKVNAGA
QFFQTNLVFDINRMEIWLNELAKRSVLDKVYILIGIAPIKSLKMAVMLSEVPGVYMPENI
IRRMDVANVAGKAQEEGVQIALELISKIKTYRGQGIHGIHLMPVGWDEVVPRLVMEAGLM
SKEVMRNYALGGVHAAEDGGVSNLR
>A0A7C5VVT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MDDPRMLPSQVVTAALAFREKLAAGHFVVGVEIDPPHGLDPRRGLRMAALMKEAGADVIH
VGDNPTARVRMSPWAFSLLLQREVGIETVMHYTTRDRNAMAIHSDMVGAHALGLRNVLCL
RGDPPEVGGYRDVIGVWDVSAVGLIRILSLLNEGIDWTGRPIGRPASFFIGAACNPNADP
LGPELRLMRRKVEAGAHFFVTQNVFEPERLSQFLGKAKAFGRPIIVGILPLNSLEHVERL
RQIPGMWLPEKVWERMRRAGPEGRLEGKAIAREMIEACRGQAAGVYLVPTQGNYDLVAEL
VAEAKG
>A0A2E9TDL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTQPASSPTSGSFRHLLEETDRFIVAVELETTRGLAMEESSSRTLSLARRLAGSNPVDLI
CITDNPGGNPHIRPEVMGYELLARGQEVVINFSCKDYNRNGIESRLWSLGSLGFDNVLAV
TGDYPITGHAGGPQPVFDIDSVGLLEVMRKMNGGLEIPSRRPGGDPSRLRQTSFFPGVAI
NPFKSTEAELLPQLFKFGYKIRTGAAWAVTQIGYDSRKLDELKKYAAVNDMDIPILGSVY
VLNAPAARVFHHGGIPGITVPDELFELVQKHADSEDRGRAFFEEFAAKQIAVLRGIGYRG
VYLSGRLPLTRIRRILDLEASFGPDDWREFSKEIQFQKPGEFNYYERDQNTGLASDQVNR
EYLESKTAKGMKRARGHVSPAYKAGRTAHGLVFDSAAPASGLARKLYWFADKRRKVGDLL
HLAEQAVKIPMYGCRDCGDCSLPDIAYLCPESQCAKNQRNGPCGGSHDGICEVGDKRCIW
VKAYERTKAYGEEETILDRPVVFKNGALRGTSAWGNTFLKRDHNAPVAIEGNGSENLANP
DAGGSANGSD
>A0A6J2TZW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila lebanonensis|TrEMBL
MLGVGACRILRVVSYQNPILMKQRHVGSAQLVERTQGVKRREWSTADSNVYALETNSSRN
SLKPYQVPDDPNYEPCVTFTPNQTERCQKPIGALLADLTAQSKFFYGIEIIPRLGGKPLP
IDFNDFLPVLPTFVSVVWLATQYWNIDPIEAVDTVQLVKHLEPRIPTLPHLTVYRMSEQR
LDDFLALNLKNLLAVRGDKVHESQPYKDSEQLVRRAQCVRGESLSIGVAGYPEGYTNEPH
GAENPLASVEAGAEFVIMQFCYRPEKIVQFILDCCAANINVPIIMGIVVPESFKTYLLME
KFVGVRLPNELRARAEELQHCPAELAKFFEELALNNIQYVLDANVGVCGVQFYTLNHLRS
TIHILKKLHEMEILK
>A0A536P3U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAAGSIPTDRRAHPFLERLRRGPLLGDGAMGTQLHARGVSFERCFDELNLTEPRIVEEIH
RAYISAGAELIETNTFGANRIKLARHGLETRVRDINFRAVKLAREAREISGEPVFIAGSV
GPIGQQLEPIGRITIAQATVAFEEQIAALLEGGADLLVLETFTNLPELLAAVSAARKTAD
LPIVAQMTFAEDGLTLSAEEPSQVVQALERAGVDVIGVNCGVGPQVALQVLEAMRQQTRL
PLSGQPNAGLPARVEGRFFYFATPEYFATFARQAADLGVAYIGGCCGTTPAHIAAMRAAL
RPIGATTPIRKPIASTAIPVDLNPAEQLPPTPFAQRLADHKFVVSVEIDPPRGLNPSKCI
AGAQLVKEAGADAINIGDSPMARVRMSALSLALMIQSQVGIDTLIHFTSRDKNLMALQAE
LIGAHALGIRNIIALTGDPPRIGDYPSATGVWDVDSIGLIKILQRLNDGYDWLGTSIGRP
ASFTIACAVNPSAEDLDHEIDRFRQKIDAGAQVAMSQPLYDLSTLERFFERTGPLPIPFL
LGVLPLQSFRHAEFMHNEVPGIVVPQPLRERMRQAGENGIAEGLQQSRELLDDTRHLIQG
VYLMPSFGRYEVVAELVRWLRQQRVATGAGSPGPAN
>A0A3D1TR40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MDKFKEALRSRILIADGAMGTMLHAAGVSLDCVLPELNLSAPDLVADVHARYVAAGADII
LTNTFRASIPRLADAGLERQARDINAAGVRLAREAAAAADREIFVAGSIGPVHTGRQRAH
MPVSERAEALREQAVFMAEAGVDLLLFETFAELDELVAGIEACAGLGLPMVGQLTFMEDE
RTLAGDEPETVAGALNTSALTVLGINCTLGPRGILSVLRRLSSCTTIPLSAQPNAGLPRM
IGRRRFQYTLHNDYFARHARLYAELGAAIIGGCCGTTPEHIHAICEAVGNLPPGRASHVA
ATGGATAVESGKRPPTLRGLLEAKRFVIGAEFHPPQGSDPAMAVQIATELTHEGADFISV
VPPSTARAQMSALSLACVLKLQTPHEIAVTITTWDRSTISLQADLLGVQACGIANVVCRT
GNPPLQGDYPNLGGIWEVDSIGLIELLRSLNQGLDSNGVPVGTPSTFFIGARVNPGASDL
EGELRRTKAKLAAGVDFLVTWPVYDLDRLSALLEGLGPERVPVLLSVQPIRDLDEAEFLR
NEVPDVQIPDELLSRLGRVQGHQPDIGKQIALELISSARDLVEGVILVNRDESPLSWGRL
INNVREVTRRAVTPDSMTG
>A0A7D6DNS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni subsp. jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEDFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A535W1X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLPAVAGGNVWRASVRSPPSAALVDPPRRCPDLASGSPWRHLAIPSARGGRVMARGSGSA
SALDAGTESAALARVLSDPTFELIPLKNALEQTSRMPTGRTVSVTASPGKTIEATVELAI
ELEGAGLRAIPHLSARMIRDRAHLATILDRLADAGIDRAFVVGGDADEPGEFLDGLSLLR
AMADLGRLPSDLGCPSYPQGHPDIPDDVLLQALHDKAELVQYMTTQLCFDPKAIGAFIAA
RRAEGITLPVKLGIPGVAEIPKLLSISARTGVKDASRFVLKNARFVGALLRSGGIYRPTQ
LLRRLALLIADPAANVLGLHVYTFNNVPATEAWRRDAEAAAIG
>A0A1A0HIM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993|TrEMBL
MATVTERIKELKPNERFCLFEFFPPKTDTGFRNLLARLHRMMALNPLFFTVTWGAGGSTS
EKSLDLAATCQKELGVTTVLHLTCTNTNKEVIDNALERAKEAGVRNILALRGDPPRTQEY
WTPNCDFKNAIDLVKYIKEQYGDYFCIGVAGYPEGHVDGANETQQNPRKDLPYLIEKVKA
GADFIVTQLFFDVDKFVAYENLLQSVPELANAILIPGLMPITTHKVFVRATKLSHALVPQ
EITDKLEAPGNDDNMVKSIGIDVLTKIISEVDRKTEGRVRGYHFYTLNLEKAVAFIIERS
PLLNLVDHNEVVDHEDAVGSDSDTEEPVRVTTRKARRSLTAEDGRLALISDALLKDRRTL
IDISTGKGVLGKDATWDEFPNGRFGDSNSPAYGEIDGYGPNLKLHTAEQIVQTWGTPETT
KEISKLFMEYLSGKIDILPWVDTEMSSETALIQEELFELNQRGWFTLASQPAVNGCPSAD
RILGWGPSNGFLFQKAFVEFFIPKKEWDEKLSSKLSQQIQDKTVTFFRGDSSGNITSNLP
IGGNNQNSKTAITWGVFPSTEVLQPTIIDYESFKAWNEEAFLLWVEWARCYKRDTKAYEL
LQSIYENYYLISMIYHDFTDELGLWTLLLTE
>A0A399Z6Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MITAPLTLNGHKVGSNLERVIRSGQFVVTGELGPPKSHDAEVIRSKAKLLKGYVDAVNLT
DNQTAIVRMSSIAAGAILVQEGLEPVIQMTCRDRNRLAIQSDLLGAAA
>A0A3L7VQI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
TGEIAPPRGASPATLLRVASNLAPAVDALNLTDNQRGLGRMSAMTAAIMLRQHGYEVIAQ
MTCQHRNRIALQSDALAGATCGVTNILAMTGDHPKIGDHPEAKNVLDVNSFQLIKMLRTM
RDEGTLQAGTPLSDAPKYFVGGVANPNIEKATRLERKITFGAEFVQTQIIFDVARFAEWM
HDVRTLGLHQQAGIMAGIMVIKSAQSARFLRDHLPGSRVPESIIERMEAAADPEAEGITI
AAELCQQLLAIEGVRGVHLMTVGWSKAIPLVVAQAGLRK
>A0A2E9A5P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MDSQKKYSPTFSFECYSPKTPEAIANLQKAQLELAKLNPDFFSVTYGAGGSTRNMTFETV
MDIREKTGIESVPHISCVGNWNDEIKTMLQNYIDNNIRRIVVLRGDLPSGSVGYGQFQHA
NELVEFIKEQTGDHFHIEVAAYPEFHPQATSAKADIDNFKRKIDAGANSAITQYFYNPFS
YYRFVDYCEKLDINIPIVAGVMPITNCTQLVRFSEGCGAEIPRWILKQLQGYGDDLESIF
KFGVDVVTELCDELLSNGAPGLHFFTMNKSFASCAIWKNLGLDKRNT
>A0A2E7B8N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp|TrEMBL
MDCRKARKRAGIRGMSTSTPHVSFEFFPPKTDAMANRLWDTVQRLEPMAPDFVSVTYGAG
GSTRERTHETVKRIAQETSLKPAGHLTCVSATKAEVLAVAEEYWQAGVKHIVALRGDPPA
GMGAKFEAHPGGFRDAVDLIKGLREHRPELGKCFEISVACYPELHPESRGWEAEIAYLKA
KQDAGADRAITQFFFEPETYLSFLDKARAGGVTMPVVPGIMLQANFRGLQRISGLCGATI
PDWLADLYDGLDDDEETRELVTANVAADLCRKLAEQGVENFHFYTLNRAGLALSTCRLLG
LKPQSAEAA
>B5IKM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp. PCC 7001|TrEMBL
MLLQQVLTRGLPAITAEVTPPRGADPQRTLAAAASLRPWVHAVNVTDGSRAVMRMSSLAM
CRLLLDGGIEPVLQMACRDRNRIALQADLLGAHALGLRNLLCLTGDPVRAGDQPDARPVN
ELESVRLLQLVASLNAGQDPVKGSLPDGGTAFFAGAAADPQSPSWSGLKARMRRKREAGA
RFVQTQMVTDAEALRRFVEEIAAPLGLPVLAGVFLLKSAKNALFINRVVPGANIPQSLID
RLAAAPDPAAEGVAIAAEQVASYLEIAQGVHMMAIKAEERIPMILARAGLTPRAAETSSP
PLAARAPQLL
>A0A3C0XFD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MASLASLLRQGEFVLTAELNPPKSAAASVVRRRADVLKGVVDAVNVTDSNRANVAMAAIP
AAVLVRDAGVEPIVQVTGRDRNRIAIQADLLGAAALGLPNFLFMSGDDPKEGNHPDAVNV
QDLSGVELVRTAASLRDGKFLNGDEVKPPPRYFIGATASPAAPQDLERTLEKIGAGAQFL
QTQPVFDIAPFSQWLTELRRREKDVAILAGVLVLRSADQAERLAAVPGITLPDAVRARMR
DAADGEAEGIAIAVETVRALHALPGVNGLHLYAIEWPEAIALVVRAAGLLPRPTVKEVVT
A
>A0A2M7PH09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_10_14_3_um_filter_51_14|TrEMBL
MNQTRAVKTDSKLEKILAAGHLAVTSECGPPRGSDSDLIKKKAELIKNHVDAINITDNQT
SVTRLCSLASCIHLKLMGLEPVLQMVVRDRNRIAIQSDVLGAASFDIRNMLCLSGDHQRF
GDSSQGQNVFDLDSMQLIQTVRRMRDEGKFLGGDEIKRPPKLFVGAAANPFADPFEIRVR
RLAKKAAAGAEFIQTQCIYNLDRFEEWMKQVRDRGLHEKVYILAGLTPLKSAGMAKYMKN
RVPGMDVPDDVVKRMAGVPKEKQPEEGIKICVESVQRLKELEGVAGFHIMAIEWEEKVPE
IVEMGGLYPRPNPDAI
>A0A359EIJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MECPKGARNGPCGGSTEEFCYVDNTRPCIWYKIYERSFKMGREEMLLEVLPPLDWDKTGT
ETWGDVVRQVKKVGTGTVAKGMLTRDAASRTATWDSVFRPVRQPEWWEGDSQYHAPAYDE
PVSELERRLKAGEFVVTSEVAPPMSTATGALCRNTDNIKPYVAAVNFTDCPSATPRMSSI
ACSKIALDRGAEPVLQIAARDRTRTGLQAEVIGAYSLGIRNILCLSGDNARMGPSPIGRS
DIIDIDSIQMLWILRRMRDEGKYXLPLPLNPNSRPSASTKKSTPGRNSSRPTWFTMPMAW
KSGSMS
>A0A3N5ME23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
KLSDGKFVVSVEMDPPRGLSAHKLLAGASLLAEAGVDVINVADSPMARMRMSPWAVCSLI
QREFGVETTLHFPTRGRNLLRVQGDLLAAHAMDIRNVFVVMGDPTAIGDYPDAMDNYDLV
PSGLIKLIKQSFNAGMDHSGATIGQPTSFFVGCALNLTPQDPQTEIKNFRRKIEAGADFA
LTQPVYQPEAAQALLKRYEDQYGPVPVPVLVGVLPLFGPRHAAFLDNEVPGISISETIHK
RLRDAGDQSPKEGVRITLELVEQMRPWASGIYLMPAFNRFDLAAEVVDGVSAATR
>A0A372RT48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus sp. MUCL 43196|TrEMBL
MKITDKINNNLETSQPFYSFEYFPPKTDEGLNNLYDRLKRMSHLDPLFASFTWGAGGSTI
DRTTEMCATAQSLYGLESCMHLTCTNVVRGTIEKAMKEAKSAGIQNILALRGDPPRGQEY
WTSCDSDFTHAIDLVRFIRKEYGDYFCIGVAGYPEGNPDSENKKQDLKFLKEKVDAGADF
IITQLFYDVNTFVEWRDECRKNGINVPIIPGIMPIQGYNSFRRITNLCKIQIPAEILNVL
EPIKHDDQAVKDYGVTLAVSMISKLRNEHNTRGFHLCTMNLEKSVRLILEKLGFVQTEEE
RNLRRLSRRRSSAGFGPNDIIRQEPDGSLPTAKPVIWKERSVDYLGRPEDWDNFPNGRWG
DARSPAFGELDGYGVSLRIPPEQALGYWQRPTTLDDLKQVFKSYILGEIPALPWYEEPLY
AETEAIRSKLVHLNELGFLTVSSQPAVNGARSDDPIYGWGPRGGYVYQKAFVEFFVSPEN
FEELVEKIKGNPWVTYCASNRNGDFRSNTKDDSPSAVTWGVFPGKEIVQPTIIAKVSFNT
WKDEAYALWTEWEHLYPKDSPSQRLLKDIGDNWWLVNLVYHNYVNSEEIWEIFFKS
>A0A1C4GAL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kosakonia oryziphila|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAVPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGGGKPEMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCAATGIDVEIVPGILPVSNFRQAKKFADMTNVRIPAWMSKMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGA
>A0A536B1L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARITDLLAAGRTVSFEFFPPKDNEEQRLLTRTIADLQPLRPSFVSVTYRGGRISRERTT
RVVVDLLRTTDLTPMPHLTCVAHPRFELGEIIGGFRAAGLENLLALGGDPLPEEESYKEL
AYASELVELGRRLGFESIGVAAHPAGHPRSPDLVSDRRYLAVKMRLADFAITQFFFKVEE
YKRLRDEMAALGITKPIIAGIMPITSLASVQRMAELSGYAVPDDIVKRVEAGGEDRDEIR
KRGIAVATELCRDLLDAGVPGLHFYTLNFSKATREIYTNLGLTV
>A0A1F5B5K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium RBG_19FT_COMBO_65_30|TrEMBL
MDKIFHVELQTPKRSSEDIEKDLRVFEEKYRKVVEAGWIVCITDNPMGLLSYGAMETIDL
LGLPVHPDQLMVHLNTFHPKKELDEILGAVKAAGGKYLLIVSGDGSQKLHRLEPAEIGVE
AVTVTSVELLRYIDREYPGRFICGVAFNPYEPQDSELEKMKRKADAGASFIITQPIIGRD
ERLSGLAPFRLPVTLDAWMSKKLHLLSECVGHEIPEGTPYDPMENLKELRRNYPDYGLYL
AILGFKTQYPLLPEIWK
>A0A535BVD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVRPLGAQSVGQALAGLLRTPRYEIFPTDGVVELVAAHVPKEVTLTVTASPRRGLPATVV
LAARLSRLGYRAVPHLSARLIRDRVELGQILDALKAAGIRNVFVVAGDAREPAGQFPDSM
SLLAALPPDHGLTEIGVTGYPESHPFIHDDVTIQSMWDKRRLATYIVSNLSFDPATIKRW
VERVRRRGVQLPIYIGMAGVADPARLLRLSTRIGMAESARFLRGHPSWLARMFRPGGYAP
GRFVSALLPDLAQPDRRVAGLHVFTFNEIEPTERWRQEMLARYAQEVV
>A0A535GY34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
RVAAYVPRDVTVTVTASPRRGMPATVHLAVRLANLGYHAVPHLSARMIRDSVELGQIIDA
LKAAGITEVFVVAGDAREPAGRFHDSVSLLSALPPDHGLTEIGVTGYPESHPFIHDDMTI
QAMWDKRRLATYIVSNMSFDPATVAAWVERVRRRGVQLPIYVGMAGVADPARLLRLSTKI
GVADAARFLRGHPSWVARMFRPGGYEPGRFVQAMAPIMARPELRIAGLHVFTFNEIEPTE
RWRREMLANVA
>A0A2D8LDY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLSKSTRLNQNKFIYTSELTPPKGIDLSKLINTASDLNMIDAFNITDNHNSKMTMAPIGL
ARKLIENNIEPIYQITCRDRNSMAIQSDLLAAYSLGINNVLCMSGESVKYGDHPNAKDVF
EISSEELIETITKLNNGYDYADNKLDSVTNFNIGAVVNPGSNTIEKELKKFENKIKNGAT
FFQTQAIYDPKTLNNIIQIKQNKNIKILAGYIPIKSVKMANFLNNKVPGIQVPENIINLM
KKTNDPQKTCIEISKETISEIKAIKGIDGVHIMALGWEHLIPKMI
>A0A535GQJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLARSKPTVSFEFMAPRDESEVDVLEHTVATLAGHAPDWVSVTYRVRTGDKTLEL
VTRIKRHYHIEAMAHLTCANTADRTRQILNWMEREGVANVLALRGDSPASGEPFTPADPL
LAHGSDLIGLVKRSGYRFGIGAACSAEKHPESPDLEHEFRYMRFKVEQGADFLITQLFFD
NRFYFDLVARARAAGIKVPIVPGLMPIPSRRSLGVMMSMSGASVPSSLQAAIDEAADDDA
VRALGVRHCIAQCAELLEAGVPGLHFYTFNRARAPIEILGALRGQQLLAS
>A0A5K1J4P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens|TrEMBL
MRVDEVFKQTAAQGTTPVSFEMFPPKGELTLDTARKVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNVSIEHLKQKQDAGASFFV
TQLFFDNEYFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A2E2ZKX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSIFPSQSKLIEDLSNSRRNCFIACDFSPPKLDNPQGLRLATSLNPDMFSVSYNPGQSVK
LNPIFASFWIQNETKISSIFTLATGNMNPKCLEKLLLNAHVLGLTNAVFVMGDSSSKTIS
ATKALELTARMNFGLDVGNNQLDTPTNFCIGSTIDISKNWDHEISLTKKKIDSGAEFFLA
QAQFDISKVVQFLESYRDKIGTHIEVPILWGVQMITKGSSSFTSIPDYMKRDLDLGRSGL
DIALEIFDQYFAYGIDSFYLLPPFFRTGKRDYDLAEELISALTSN
>A0A2E7VU27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIINIINKKKTLSFEFFPPKTESNLGNLNKTISDLSEFNPDFVSFTYGAGGSTRKLTLE
ISQKTKESEITEVMSHLTCLTHSKSEIIEMLSAYKKSNIENIIALRGDIPNNSNDLKKEI
HHATDLIEIIKNYSDDFCIAAACYPESHPESISKNDDLKFTKLKQSKGADFFITQLFFNN
SDFFSFREKAIKLGITIPIIPAIMPITSTXQIRKFTNLCGASIPDSLNKKLENSINNDEE
TTKFGIEFATMQXNELLNNDIPGIHFYSLNKSRSVKEVLNNINI
>A0A661WFN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIMMVINNNSPCSKLEEILRAGYFAVTAELNPPDSADPEDVYKAAGILANVCDGINAVD
ASGANCHISSVAMCALLTRAGYEPVYQVTCRDRNRIAIQGDMLGAAAMGVLNVLCLTGDD
VTAGDQPEAKRVFDFDSIQLLRTARTMRDEATFLSGRKITSPPCFFLGAAANPFVPPYDW
RPQRLAKKIAAGAQFIQTQYCFDLPRFKEYMTQVRDLGLDKQAFILAGVGPLKSAGAAEF
MRTKVPGVVIPDQYVDRLKKTPKEKQQEEGKKICIELIEQIREIDGVAGIHIMAYRQEEL
VAEIVEQAGLMPRPTSNDQNKG
>A0A847MYZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MQVIDILNEAKKPLFTFELVPPLKGSDAQSLLGSVRELAQFEPAYINVTNHQQEVVYLER
EDGLLERRTVRKRPGTIALSALIQYTFNIPVVAHLICGGMDSDQLEDALVELNFLGIENI
LALRGDPPNGEKRFVPMKGGYAHSSDLVKQITNLNEGRYLDSTLQDGRKTHFCTGVAGYP
EKHAEAPNLEEDIQMLKYKVECGAQYIVTQMFFDNAVFYRFVDDCRKAGITVPIIPGLKP
IGSKRDLATIPQTFHVDFPSELVQLLNKAQKLSEIREIGVYWCTKQAKDLLEHGVPGVHF
YTLGKAESVSRIVREVF
>A0A7X8EEA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MRVTEIIQAAKKPLFTFELVPPLKGRTLEPILETIRTLMEFDPSYINVTNHQAEVVYLER
EDGLLQRKTVRKRPGTTALAALIQHTFNVPTVAHVICGGMSREQIEDTLIELHFLGIDNI
LALRGDPPSGEKRFIPMSDGHTYSSQLVKQIADLNHGRYLDDQYQDGEATHFSIGVAGYP
EKHAEAMNMAVDLANLKKKVDAGAEYVVTQMFFDNEKYFAFVKACRAIGITVPIIPGLKP
LASKRDLSLIPQTFGVDLPEELTAELEGGASNAEIAEIGVRWCIAQSKELYASGVPSIHY
YTLGKAQNVARIVRAVY
>A0A432QM02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp|TrEMBL
MKPDFVDYIQEHVVLADGALGSYLFERGVERGRNLDLLNLQAEETIFSAHEEYIRAGSQL
IETNTFGAGRFKLREAGAEDQVREINRAGARIAAKAAGHQVYVAGSIGPTGETFPLDEGE
VTEEEIRASFTEQVLGLAEGGADVLILETFSQLQEILLAIEIARREAPELPVIAQMVFPA
RSMTVHGEDALTCGRRMRAAGAVVVGTNCGRGIDAMVTAVARMSPLAGEGTPLSAFPNAG
MPEMVGGRTIYPAQPGYMAARAREMIKSGVHLIGGCCGTTPAHIQEFRSALRIKPVRVRG
ERVAAVDREADGVEKPFKTGGFLESLDNKRLPIIVELDPPTHLDVDSVLHGAEELTRAGV
DAVSLGESPLAILRTGNLGMAARIRQRCGVQTIIHQTGRDLNGLGLQSRMMEAHLLGIEA
VLAVSGDSAAGTDQPGVTGVFDLRSEGLIRMLAGLNRGMNLAGRSIKKETNFSIGAAFSF
RPAKPGLQISRLEKKNALGARFAMTQPLFSREVVEQMMEAVNHIDILIFPGIFPLISARN
AEFLHNEVPGISVPADLRARLASYDQVADQRKAALEYTGRLIEDILPSIHGLYLISPLNK
WDIVLDFVHQVRGTA
>A0A812SXV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiodinium microadriaticum|TrEMBL
MAISEYATKYFGVEVLMHLTCSGQTRDQIRQTLLEAKEAGIHNILALRGDPPKGALTWTP
SRNGFERALDLVRFIRQEFGDFFGIAVAGFPEGYPQSSISMTEQIGFLKEKVDAGADFVL
TQFFYDPAVFLSFVERCRAAGVTCPIVPGMMPIQNYSSFQRMTSFCRTSVPQCIYESISP
IADNDEAVKAYGVQLCVSMCQELMRQGIRGFHFYTLNLENSVLSVLSSLNVVESTGMTED
VRPINWANRPKSYIARTMGWDEYPNGRWGDSRSPAFGELSNSHFFGTTVCSKEDRLTMWG
EAPLSAEELGGKIPILPWCESALQTETGTIAPFLLELNRKGFFTINSQPSVNALRSDHSV
YGWGGPGGRVYQKSYVEFFTRPAYLKCLIAALPHFPSLTLHAVDCNGQINSHTSHGGARG
VTALTWGVFPDKEILQPTIFDPNTFAVWSKEAFQLWIEAWAVLYDDETDSAALIHEVHDT
YFLVAIIDNEFIDSDMYAIFKHVLKRIEEVKIFDDLSDDSAADDDTGLVV
>A0A7S1XAA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Compsopogon caeruleus|TrEMBL
MAMVGSVVEVELSPRVDFNLRDTAKISDKIRRREEEGKLFFSFEYFPPKTATGVDNLYER
VERMAQVEPLFCDMTWGAGGTTSDLTLDLSGNIQRYLGLDVMMHLTCTNMPQGAVQVALE
SAKARGIRNILALRGDPPAGQEWKACEDGFAHAEDLVRYIRKHYGDFFSICVACYPEGHP
AGFLDGKLTFAEEMAHLKAKVDAGADFLITQMFYDVEEFLEFVGKCREIGITVPILPGIL
PIQNYAGFKRMTGFCRTKIPPEVAEALDPIKDDDAAVRRFGINLGVDMCRKIIRSGLVPG
IHFYSLNLEKSVMAIIEELGLVSRTESIRSLPWRPATWDKRRLETVRPIFWANRPRSYLD
RTAEWDEFPNGRWGDSRSPAFGDLSDYHLMGGAGFLSPELKARYMEQLGTISSVEDVTRI
FVDFCKGEISRLPWVEGENFAPETKAILGPILWLNQHGLLTINSQPRVNGAPSGDITVGW
GGPGGYVYQKAYIEFFCDRAMMERLLEESKKFGSLTILAVRCESSEILSNVKKPRTNAVT
WGVFPNQEVIQPTVVDPVSLLAWKQEAFDLWMSAWGNLYPEDSKSREVLKEIQHSYFLVT
VVDDDFVAGDIFKIFSAVIKSQ
>I1BPZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)|TrEMBL
MKVIDKIKRAEQEGRSFWSFEYFPPKTPQGVQNLYDRMERMQRYGPEFVDVTWGAGGTSA
DLTTEIVATAQSVYGLETMMHLTCTNMPVQQIDDALEAAKKCGCQNILALRGDPPKGQAN
WESCESGFEHAVDLVRYIRQKYGDYFCIAVAGHPEGHIDNPDKEDDLLRLKEKVDAGADL
VVTQLFFDIEAFITFYHKARAIGIECPILPGVFPIQNYSGLKRVIAFNDNFVPQKIWDEL
ESIKEDDTAVKEYGINLTVDFIKRFRQEGINGFHLYTFNLERSSRLVLERLELVAPIENI
KPLPWSPSLNNKRAKENVRPIFWKNRTKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
INLRYPVEQCIKMWGTPKSADDIASTFARYCKGEIAGIPWSSQQLDAETEIIRQRLSAIN
LLGYLTINSQPAVNGVKSSHSVYGWGPKNGYVYQKAYLEFFVSPDKLPELIAKIDKDPQV
TYYAVNKQGDLRTNTQSDEPNAVTWGVFPGKEIIQPTIVEAIAFMAWKDEAFELWSRWAR
IYERESESAELILDVTNNYYLINIVHNDFQDENGIWRLFDLEIDGEISRKLLQSSVAR
>A0A347UE88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Profundibacter amoris|TrEMBL
MATPRISFEFFPPQSLEASFRLWDTVQVLAPMNPNFVSVTYGAGGTTRDLTHEAVTTIQN
NYGLKVAAHLTCINSTRDEILAIADKYAKAGVTDIVALRGDAPKGADGFKPVEGGFTSSI
ELVETLAETGKFNIRVGAYPEPHPESPDTAADVEWLKRKIDAGASSAITQFFFEAETFFR
FRDACEKAGIDAPIIPGIMPITSWTGIKKFAAGCGASIPTWLDDAFTKAIRDGRTDLLST
AVCTELCSDLIDGGVEDLHFYTLNRPALTRDICHALGVTPAVSLENVA
>A0A5C6YYZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aequorivita antarctica|TrEMBL
MKVTEHIKNGNGKTQFSFEILPPLKGENIHSIFNNIDPLMEFEPPYINVTYHREEYVFKE
LKDGLIEKKIVRKRPGTVGICAAIQNRYQVDAVPHILCGGFTKEETENFLIDLQFLGIDN
VMALRGDAVKSETYFTPEKNGHKYACDLVSQINALNKGTYLDDELQNTFPTDFCVGVAGY
SEKHMEAPSSESDIHFLKKKIKNGAQYIVTQMFFDNDKFFQFEKKCRAEGITVPIIPGLK
PIAVKSHLNLIPHRFKVDLPDALVMEIVKAKDNKAVRQIGIDWCVKQSQELVKAGVPFLH
YYSMGKSSNIREIASQVF
>A0A2T4CGN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma longibrachiatum ATCC 18648|TrEMBL
MHIRDLVADTEKSGAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLEKVNDALQKAYKAGCTNILALRGDPPRDQAS
WKAADGNFQYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGAGF
IVTQMFYDADNFIRWVGRVRERGITVPILPGIMPIATYASFLRRAKHMQCRIPPDWMAKL
EPVKNDDVAVREIGKTLVADLCRKLLANGIHHLHFYTMNLAQATRMVLDELNWTPSPERP
LKQALPWKQSKGFGRRDEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKKWGEPKSVQDIATTFVQYLEKKIETLPWSESALSAEADPIKDDLVA
LNKRGLLTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLMPPYLLEEMIRRLDDFP
NLTYYAVTKNGELKSNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGVDW
AHCFDAGTPSRALIEDIMNNWYLVNIVNNDFRENNTIFALLEGLEVKDLAVPAGTTSVSD
TA
>A0A428TI42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sp. AF-4|TrEMBL
MHIKEMLTDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRDQDK
WTAADGGFQYARDLVKHIRSTYGNHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKKVRERGVNVPILPGIMPIATYASFLRRANHMKAKVPQAWLDAL
EPVKNDDVAVRDIGKSLVAEMCRKLLANGIHHLHFYTMNLAQATRMVLEELNWAPSAERP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTVQDIAQLFVRYLRNEIDSLPWSESPLTSEADEIRDDLVE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPSNGYVYQKSYLELLVHPDVFNDMIGRIEGHP
DLTFYAVTKDGELRSNAPSDCPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDASSPSRALIDEVMNEWYLVNIVNNDFHQNGTIFELLKGLEVKDLTTPATPKSEPE
ANGTEPLANGAAAA
>A0A2W2EXG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spongiactinospora gelatinilytica|TrEMBL
MSLGRPSVRPDRVPTVRELLASGDRSFSFEFFPPKSEEGERQLWRAIRELEALSPTFVSV
TYGAGGGNRDRTVGIVERVAHETTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVR
GDPPGDPMGEWVQHPEGVLYAEELVRLIRQSGDFCVGVAAFPYKHPRSATIESDTDFFVR
KCRAGADYAITQMFFRADDYLRLRDRVAANGCDTPIIPGIMPVTRMSTIARSEQLSGAPF
PEEVAARFEEVKDDPEAVRRLGIEHAAELCRRLLDEGAPGIHFITFNRSSATREVFQRIA
PVPAAASVSV
>A0A653XHU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plantibacter sp. T3|TrEMBL
MTTTEPACPRRTPFSFELYPPKTLDGGVALARTVEHLAAAGPEFISVTFGAGGSSRTASL
DVLRSIRTSTSVDPMAHLTCVGSTHAQASRLIKDFLDAGVHSFLALRGDPPAGAVEGDAF
LGDLGSAAELVQLIGRVSAEHEPYAEGSLAGLPGAVQLGRRRRPRIAVAAFPNGHPRSRS
TTQDLDTLLAKQAAGATLAITQLFFHADDYLAFAERARRHGVTMPILPGVMPITSPARLH
RVLELSGEALPSDLAIALEVEPDEAGRIDIGTEYSARLIRDVVAGGAPGVHLYAFNQHRT
VLDVLHRAGIPMQGDRPVRHPIPDPLTSKDAR
>A0A3A8ERX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter tianfuensis|TrEMBL
MSLLSSYLQSGQFCILVEYLTSLNEVFPVRNQFAGYPAVMTLADRVHSDHDVSPLEASKK
YPKDAEKVLHFAGKGRDIQDFERFLAQAKIANIQNLLLLTGDKLKEHQNGNNAVERSRYL
ESVNAVMAAKKAGGFCIGTAFNPFKYAEAERDAQYLKLHKKIKAGADFIITQLGYDIAAL
KQARAFLKQHHYAQNILACVMPLSWARAKFMLKHKVAGIVITPHMFKVLADEKEAGLSEQ
VYLRCALQILICKQLGFAGVDLSACHKPEEQMLLERYIEQYSHLDLDALERLWNQLWKIQ
SGHEFQPELNYFSRPPSSSQLIKYHHLHLMHDALFDSKVARGLGRFIFKASFWERASAAK
TLLKTEYISKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVQQTQVLKEKLIPAVPIAVRGSSSWKNWYLAEEA
>A0A845H971|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp. TS35|TrEMBL
MSSKQTVSLEFFPPRDIAAQEKLVRSAKQLLAVRPEYVSVTFGAGGSTRSGTADTVRMMQ
NLGCDAAPHLSCIGATRAVLGEILDAYRQHGVRRLVALRGDLPSGMGGDAGELHYASELV
AFIRQHSGDWFHIEVAAYPETHPQAASGQADLAHFVHKVNAGANSAITQYFFNADAYFDF
VDRARAKGVTVPIVPGIMPITNHTQLARFSTMCGAEIPRWVRQRLIDFGDDKASIKAFGV
DFITRMCQQLLDGGAPGLHFYTLNSAEATLAICQHLRLN
>A0A7K0ERK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Larkinella terrae|TrEMBL
MAKVSDHIRQANGKTIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PEPDGTIKKIITRKRPGTVGICSAILHKFGVDPVPHVLCGGFTKEETEDFLIDLHYLGID
NVLVLRGDPAKPFSTFKPKANGYSYASELVAQVTNMNRGIYLHEGENAMAPSNFCIGVAA
YPEKHFEAIDHDTDFKYLKLKVENGADYIVTQMFFDNRKYFDFVKRCRQEGITVPIIPGL
KPLSTRKQLQVLPRLFHLEMPPDFVKAVEVCENDTQARQVGIEWCVQQCRELTQAGAPGL
HFYTMGKSDNIVKIAREIF
>A0A6N7Y980|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. McC-251-APC-3A2|TrEMBL
MSQLINKLKQNILVADGAMGTILYSDGLDTCPEAYNLTHPDKIERIHRSYIESGADIIQT
NTYGANFEKLKVFGLEHKVKEIHKAAVQIAKKAANDETFILGTVGGFRGVKQEDLGLEAI
QYHTEIQVDTLVEEGVDGLLFETYYDLEELTNIIKATKRKHHIPIIAQLTALNTNYLRDG
TEINTALQRVVDSGADIVGLNCHHGPHHMQQSFSHIELPDNAYLSCYPNASLLDIENSRF
KYSDNAEYFGKVAEQLIKEGVRIIGGCCGTTPEHIQYIKSSVANLKPVSSKNVIPIKKYN
SPSYANTQQQNLTTKVKAQPTIIVELDTPKHLDTETFFRNIKKLDDAQIDAVTLADNSLA
TVRISNVAAASIIKQQYNIEPLVHITCRDRNLIGLQSHLLGLSLLNVNEILAITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNEGINTDGDALKTKTNFNIAGAFDPNVRKLEGSVKR
AEKKIESGTHYFITQPVYSTEKIEEIYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEDILEQFEAVKDDKEKTKALSLKLSKELIDTVHKYFNGLYLITPFQKVDYTLALASY
SQSITSSKQEAIL
>V8BP45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella oralis CC98A|TrEMBL
MKIIDIINKNTDKRRFSFEVLPPIKGNGTGSLFSTIDKLKEYDPLFINITTHHSEFVYKE
LPNGQFERQRIRRRPGTVAIASAIQTKYNIPMIPHVICSGVTTEEIEYELLDLQFLNIEN
VLLLRGDKAKEDNHFVPTHGGHAHTTDLIKQVNRFNEGFFMDGTPMKHPGMPFNYGVACY
PEKHEEAPNIEMDMEYLKKKQDLGAQYAVTQLFYDNKKYFDFVEKARTMGITIPIIPGIK
PFAKLSQLSIVPETFHCDLPQELANEVVKCKTDEDAKTLGIEWSTHQCKELYAKGVGIIH
FYTVSATDAVKEIVSKIM
>A0A220VCA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraphotobacterium marinum|TrEMBL
MKYHYNNYLDSLNNNLLDISHKVDISFEFFPPKTEEMKTQLWESLNKLVPLNPSFVSVTY
GANNGERANTHKIIEEIVRNTDLIVAPHLTCIDTSRNQLRDIAKNYWSLGIKHIVALRGD
YENTNSIMMYAADLVQLLKEVADFDVTVAAYPEVHPEAKNAQADLVNLKKKIDMGASRAI
TQFFFDIDSYLRFRDRCVSIGIDAEIIPGILPISNYNQAYKFAKMTNVHIPKWIKKQFEG
LEEDPLTRKLIGASVAIEMVKSLSKEGVNNFHFYTLNRSDLTFAICKVLGVIKAS
>A0A1C5PCF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKIRDILAQGRPTLSFEVFPPKTEDAYDTVERAAAKIATLKPDFMSVTYGAGGGTSDYTV
GIASDIQKSGVTPLAHLTCVSSTRDKVHSVLEELKNHGIENVLALRGDIPADGRTPREYH
YASELIHEIKQSGDFCIGAACYPEGHVESANKSVDMDYLKEKVEAGCDFVTTQMFFDNSI
LYSYLYRIREKGITVPVIAGIMPVTSAKQIKRITQMSGTYLPSRFLAIVDKFGDNPAAMK
QAGIAYATDQIIDLIANGVRGIHVYSMNKPDVAMKIRENLSEIL
>A0A0S8GPA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium SM23_30|TrEMBL
MSKLQEALTANKFVVTSEVGPPKGVAVERYLEEAAALKERVTAFNVTDLQSAVMRFGSMA
TCRLLLDRGMEPVLQMTCRDRNRLALQSDLLSAYGLGVENVLCLTGDHQKLGDHPQAKGE
PQEAHLFKMEKKIDAGAQFFQTQAVYDTEKFKAFMKKGSHLKAPILAGIVILKSVGMARF
MNANVAGINVPEELIEELKKDKEKTKSGRTGVEIAARIIKEIKDYCQGIHLMPLGWDDKV
PAILDGAGL
>A0A430EL14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. ABOLE|TrEMBL
MAPPLFADVAGDVAVSFEFFPPKTEKMEETLWASIETLSPLGPRFVSVTYGAGGTTRERT
HATVSKIARETPLAAAAHLTCVEATREEIDQIAEEYWAAGVRHIVALRGDPPRAGEKYRT
HPGGYENAADLVAGLRRLHPFEISVSAYPECHPDSPSPEADLDNLKRKIDAGANRAITQF
FFEAETFLRFRDRAAAAGIDAEIVPGIMPVMNYASVVKMSAMCGTDVPAWMEKLFEGLDE
HPGARQLVAATLAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGLRPRQQAAVAAA
>A0A1L3STA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquibium oceanicum|TrEMBL
MSVSDQNPAGLDLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANAQDVYDRAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGFAPIMQISCRDKNRIAIQGDVLGAAAMG
VGNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRIMRDERKFLSGRKLTTPPEVFLGA
AINPFAPPFDFRPHRLAKKVAAGAQFVQSQYCYDVPMFREYMKRVRDLGLVENCFILCGV
GPLASARTAKWMRTNVPGVHIPDAVIARLEGAADRKKEGKRICVDIINEVKEIEGVSGIH
VMAYRQEEFVAEIVDESGVLKGRRPWRREAGADDARVAEKLDRILHEEDAQSPGDLVRQA
AG
>A0A257JBN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium PA3|TrEMBL
MTMSLASLQEARRALDTPLFADLAGDAQVSFEFFPPKTERMEEQLWETFQTLEPFNPRFV
SVTYGAGGSTRERTHGTVARIAKDSNVPAAAHLTCVAATK
>A0A0X7B9H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. TAB 87|TrEMBL
MKVTEHITEAKGKTLFSFEIIPPQKGKNIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFIPKAGGNCFATDLVKQIDDLNKGRYLHEMMDIDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNSKYFEFVNKAREIGITIPIIPGIK
PIAVHRHLQVLPQIFRIDLPEDLIDAVEKCKNNADIRQVGIEWAIQQSKELKEAGVPVLH
YYSMGKSENIRQIASTIF
>A0A1V2YHB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epulopiscium sp. Nuni2H_MBin001|TrEMBL
MKINLTKPIFSFEIFPPKKEGVWLQEIYNTIDALAPLNPDFISVTYGASGSSQDNTVEIA
SLLQKKYKIPSVAHLTCVCDDNENIERVLDRFKEEGVENILALRGDLPDGATLGKFKYAS
ELTEFIKSYGDFFVAGACYPEKHLEAYTPEEDIKNLKIKADSGAQLFISQLFFDNAKFYS
WIEKVRDAGITTPIMAGILPITSAKQLERMVTLCGATIPEGIQSIIKAYNHNAFALKEAG
IAYASMQIIDLLAHGVDGIHLYTMNKPGVAQRIVDNIKGPLYSLKQS
>A0A6J7MUC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MNSKLRGTTFSLEFFPPKDEAGESRLWLALSQLQPLAPDFVSVTYGAGGSTRDRTIRVTS
EITKRTSIPTVAHLTCVGATRDELVEILNQFKNSGIDSILALRGDPTGGPTAPWQMIPNG
LNYARELVELAVGMGFKAGVGAYPDGHPASNHDLAKDIEVLLAKEKAGATFATTQFFFEI
DKWQAIVDKLAKAGSKLPVLAGILPITNVKQLNRMVELSGMKVPTAIADQFSKYADDLEA
TKEIGIEIATNLGAQLLKRGVPGLHFYTMNSAQSTVAIAKNLGLIK
>A0A6J7D900|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MKTTYSFEFFPPKDVDGEARLWKAMAALETIAPDFISVTYGAGGSTRDRTIKITSEITSR
TNIPTVAHLTCVGSTKSELLEILGRYQSSGIKSILALRGDPTGGPRAPWTSTPDGLNHAD
ELVKLAADFGGFEIGVAAFPDGHPASNGNLDIDIDVLIRKESLGASFATTQFFFEADKWK
SLVDKLAAKGSKLPIIAGILPVTNVKQLNRMSELTGTPIPSRLSGAFEKVQDNPEDVYKL
GVEVATKLSQDLLNAGVPGLHFYTMNTSNATREIYANLKVGDR
>A0A6J6HD47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MAIRATKYSFEFFPPKDQAGEERLWAAMEALEPMAPDFISVTYGAGGSTRDRTIRITSQI
TERTSIPTVAHLTCVGSTRGELIEILQKYKEAGIRSILALRGDPAGGPSAPWAPTIGGFN
HADQLVELAMEVGGFEVGVAAFPDGHPASNGDLAKDVDVLIRKEALGASFATTQFFFAAD
KYQRLVEALAAKGSSLPIIPGILPVTNVKQLVRMSELSGTDIPAEILVKFSAVENDHEAV
RRLGIEIATELCEQLLELGVPGLHFYTMNTSSATLEIYQKLVAK
>A0A7Y1V3K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospiraceae bacterium|TrEMBL
MKVTKYFEEAKGKSLISFEVLPPLKGGSMQSIFDVLDPLMEFKPPFIDVTYHREEYVYQK
SGNGYYEKASIRKRPGTVGICAALMHRYGVDAVPHLICGGFTKEDTENALIDLNFLDICN
VLAIRGDARKFDGRFLPEEGGHSYALDLVRQIVEMNEGRYLDSNIENGARTNFCIGIAGY
PEKHFEAPNFQSDLKYTKNKIDAGADYIVTQMFFDNKNYFDYVDACREKGIDVPIVPGLK
PLTKMYQLKSLPRMFYVNMPEALVKEIEKVKKPEHAKEVGIEWCITQSLELKEYGVPCLH
YYTMGDVDTIKRIAKAVF
>A0A7S6N255|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriales bacterium|TrEMBL
MKVTEHLDRAKEPFISFEIIPPKRGGDIKSLLAVIEEISKFKPPFIDITSHSAEIEYVET
KTGIEKHVKRKRPGTLGICALIQNKYNIDAVPHILCKNFTREETEDFLIELSYLGIDNVL
AIRGDDNGFQKPVPAGRSANNYAIDLVAQIAAMNSGKFLEDGLLDAKPTSFCIGISGYPE
KHFEAPNLKTDILYTRKKISTGADYIVTQMFFDNAVYFQYRDACAAEGVNVPIIPGLKII
TAKSHLTNIPRNFFINLPPDLTGEVMEAKNNEHVMEIGVNWAAKQVIDLLDKGVPSIHFY
IMQNAKPINLLMQKLKLHKQYYFIAG
>A0A6J6JGZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRLEKRMYSFEFFPPKDLAGEERLWQALSSLATLSPDFVAVTYGAGGGTRDRTIRITSEI
TARTKIPTVAHLTCVGSTRDELIDILARYKESGIKSILALRGDPVGGPRAPWTPVDGGLT
HADELISLAREHGDFTIGVAAFPDGHPNSGGDFNKDVEVLLRKESLGASFATTQFFFEVD
KWKRLVDALEKRGSTMPIFAGVLPVTNVKLLTKMAELGGTPIPESIAARFAAVEDNPDDV
RKLGVEIALNLCNELIDAGVPGIHFYTMNSSTATSEIFASLKDRR
>A0A6J6ZG10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MKKIGEGVTYSFEFFPPKDPEGEERLWSAMGALEPIAPDFISVTYGAGGTTRDRTIRITS
EITQRTHIPTVAHLTCVGSTRDELIEILGRYKQAGIHNILALRGDPTGGPRAPWTPTPGG
LNHADELVTLAAEVGGFTIGVAAFPDGHPASGLDFAEDIEVLLRKEEAGASFATTQFFFE
ADKWKALVDRLAARGSKLPIIAGILPVSNVNQLNRMAELSGVPIPTSIADRFAALKESPE
DVKKLGVELATQLCEDLLTAGVPGLHFYTMNTSSATREIFEQIKDKKRG
>A0A1E5GWB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus quebecensis|TrEMBL
MRTDDLFKEKTVFSYEIFPPRRTAPIDTIYHTLDRLKGQQPDFISVTLGAGGSGDNLSTA
DIAQKIQDEQFLPSVAHLPAVNFSKEEIITILEELKQKKVENILALRGDILPDKKPKKDF
KHANDLVTFIHEQGEFNIIGACYPETHGDAENSVEDIKNLKRKVDSGTNQLITQLFFDNN
YFYTFKEKCDIANIDVPIQAGIMPVVNKKQIERMLKMSNVTLPHKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVAQGADGIHLYTMNNPYVAQKIREATRSLFEVESKLSLILK
>A0A2X4WC91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lederbergia lenta|TrEMBL
MTLLSSLQEQILIGDGAMGTLLYSHGIDRCFEELNLTHPEEVARVHRAYLDAGSDVIQTN
TYGANYIKLSRYGLEENVKRINSEAVRIARETVGNDAYVLGTIGGIHGSGIRFGKTEEIK
RSFREQLYCLLLGGVDGLLLETYYDLEELTTVLKIAREETDLPIITNVSMHEPGVLENGI
HLSDAIVSLEDLGANIIGVNCRLGPYHMVKALESIPIPQKAYLSVYPNASSPEYRDGKLL
YKTEPDYFKKFARNFRDEGVRLIGGCCGTTPEHIRALSEGIKGLKPLKEKEVKKQRTIEV
AKITQQDGQTLFEKVKTKRSIIVELDTPKHLDTKKFFEGARALKEVGIDGLTLADNSLAS
PRICNMTMASIVNREIDLPALVHITCRDRNLIGLQSHLMGLHTLGIRDLLAITGDPTKIG
DFPGATSVYDVTSFELIKLIKQFNEGISLSGKSLKEKTNFHIATAFNPNVRNVGRAVERL
EKKIGYGADYVVTQPVFSEEKLIEVSEATKHITAPIYIGIMPLVSTRNAEYLHNEVPGIK
LPDEIRLRMAATAQSSDRAIQEGLSIAKELIDTAMEHFNGIYLITPFIRYDLTVELTKYI
QRKEKELAKSKKSQFVI
>A0A6J6TPU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRASSWPSCRRTEETTDWTRERNSAGSRTDSATPQSLWGFDDSGFSSTLGYDRRMREEGA
GAGSDASRRSLGEVLSTGSRSFSFELFPPKTDDGERALWQTIRDLQGLSPSLISVTYGAG
GSTRDRTVRIVGGIAAEPALTPLAHLTCVGASREEVRAVVDEFAAAGVRAILALRGDPPG
GPGSAWVQHQDGFAHADELVEFIASMGNFSIGVAAFPEGHPESANLADDAVVLARKQDAG
AEFAITQFFFDARDYERLVRDAAGHGCTMPILPGLLPVTNVAQIERFAALSGAAFPADLA
ARFALVKDDPDAVHSLGVEVAAELGQKLLEMGAPGLHFYTLNRSASTLEVCEALGLGAR
>A0A2D6QA37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon|TrEMBL
MRIIDLYGQGRPIFSFEFFPPKTDAGENKLMETMADLKSAVEPDFVSVTYGAGGSTRDRT
HGVVTRIQNELGITGMAHQTCVAASRTDVLENVKRLVASGVQNVLALRGDPPDTDGDWQP
PADGFSHANELLEFLTAEFDLSLGAACYPEVHPEAASAEDDLAWTREKVKSGAGFLTTQL
FFQSDCYVQFVEHAREAGISVPIVPGIMPITNLGQIERFTKMCGAELPAELRMRLQRCGD
DAAAVMATGIEHAITQCRELLEAGAPGLHFYTLNKSHATRSILAAMRQL
>N9PL00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 102136|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHNVAGIVITPHMLRALAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVKT
KNELVPELAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDLCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A842SER6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon|TrEMBL
MGMTFKQKLTENRFVKTLEIAPPKGSDLSKVVNIAKKLRNYVDAFNITDNQRAMLRMSPL
ALSSIFIKNGMEPVMQMTCRDRNRLALKSDLLGAYALGIRNILALTGDSIKAGNHKDAKQ
VFDIDSVHLLKIISDMKNSDKGKTNIEFLAGAAINPNSDLLDGQIFKMKKKIDAGASFFQ
TQPVFSKKVFFNFINLLESEKIQTKILAGIFVLRSAKIAEFMNIKIPGITIPDNIIKKLK
ASSNPEKTGIEIAVKTINKIRDECEGIHIMAMGKYDSLPYLFKKI
>A0A443RZH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrombidium deliense|TrEMBL
MKISGSLKEKLIQHIASSDLPFFSTEFFPPQTVEGIKNVISRIENVKEGNPMFCDITWHG
TGNPEGKGNTSSLSIAEMALNICGLETMSHITCVSVNKQELDAYLKKLKQVG
>A0A7Y2HE42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospiraceae bacterium|TrEMBL
VLPPLKGGTMQDIFNLLDPLMEYKPPFIDVTYHREEYIYKQQPSGYYEKFAIRKRPGTVG
ICASIIHRYGVDAVPHLICGGFSKEETENALIDLHFLGINNVLALRGDARRFEDKFIPDP
EGHKYAVDLVKQITKMNKGIYLDSNIEGGASTDFCIGVAGYPEKHFESPNLDLDLNYLKD
KVDAGASYIVTQMFFDNSKYFEFVDACRSKGIKVPIIPGLKPLTRKYQVNSIPRKFYVNM
PDDLINAVMKTKSKEEVVEVGIEWAVAQSKELKEAGVPCLHYYTMGDAATTKKIVDQII
>A0A094Q589|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSTLEHKLTKTTETVFTAEFHTLDGNGLEKAKKYADRFRGWFDGVNATDNTAAHAHVSNV
ASAIAMKQLGLEPILQVVCRDKNRLAQQADIMGASMFGVENFLALTGDDVTAGDETEARR
VFDLDGPQLVRLMSTIKRGEYMSGRKIDPAPHMFIGAVENPGAPPFEYRVQRVAKKYASG
AKFLQLQICYHQDRLEKFCAGVRDAGLAGKIAIIPTIVLIKGARPLNFMHNSVPGIDIPA
DQIARVEKATDPSEEAYLQTLEFAQHALAQPAVRGLHITDFRNDETLERLMTDLGRVRQS
ITSEVKDNHAYSA
>A0A6J6LJ82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTQSAAGANLAQLLATGGRSFSFELFPPKTDEGEQALWRTVRDLERLNPTFVSVTYGAGG
SSRDRTVRITAEIAEQTSMIPVAHLTCVGASREELRGVIGEYAAAGIHTILALRGDPPGG
PTAKWTPHEDGLQHADELVELIKALGNFTVGVAAFPEGHPSSPDLDTDARVLAAKQDAGA
QFAVTQFFFRSRDYADLLERATAHGVTMPIIPGLMPVTNVAQIARFADLSGAAFPPELAA
RFELVKDDDDAVRKLGVEIAVEMSNELLAMGAPGLHFYTLNRSTSTVQVYEALGLGSR
>A0A1V4E4N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. GKU 895|TrEMBL
MALGTASTRTDRARTVRDILATGKTAYSFEFWAPKTEKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRATEQIAADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDTDVEHFVD
KCRAGADYAITQMFFKPESYLRLRDRVTAAGCATPVIPEVMPVTSVKMLERLPQLSNASI
PSVLKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A2N1L152|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma harzianum|TrEMBL
MHIKSLVAETEKSKAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLEKVNDALQKAYKAGCTNILALRGDPPRDQES
WTAADGNFQYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGAGF
IVTQMFYDADNFIRWVGKVRERGITIPILPGIMPIATYASFLRRAKHMQCRVPPDWMAKL
EPVKNDDVAVREIGKTLVAELCKKLLANGIHHLHFYTMNLAQATRMVLDELNWTPSAENP
LKQALPWKQSKGFGRRDEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPASIQDIANTFVQYLEKKLETLPWSESGLAAEADPIKDDLVA
LNKRGLLTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLMPPYLLEEMISRLDDFP
NLTYYAVTKNGQLKSNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGVDW
AHCFDANTPSRALIEGIMNEWYLVNIVNNDFRENSTIFGFLEGLEVKDLAVPVTPTA
>A0A0M5LQZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. AL041005-10|TrEMBL
MTTSSASTVTERINVDRPFFAVEFFPPKDDRGEAELWRAIRRLEVLDPAYVSVTYGAGGS
SRDRTVRTVERIATDTTLCSMAHLTAVSHSTDELRHVIGSLAAAGVRNIMALRGDPPGDP
LGEWVAHPEGLEYADQLVALIKRSGPFCVGVAAFPYGHPRSADLDADTERLVGKFRAGAE
FAVTQLFLEPDGFLRLRDRVAAAGFDQPIIPGIMPLTSEKTFHKGPELSGSPLPAALVER
LAPYSGDTAAFRAAGMEVTGELCERLLAEGVPGIHFYCLNRSTATTELVERLGLAPRHEG
TRLSTPA
>A0A1Z9YG26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium TMED5|TrEMBL
MSLQHAPKNIHVSFEFFPPKTEKAEDKLWESVRRLEPVHPEFVSVTYGAGGSTRDRTHRT
VKRMVEETNLVPAAHLTCVSASKAEVMGVVDDYLDAGVQHIVALRGDPPEGMGAKFEAHP
EGFSGSIELIEAIRNYKPALGKRFEISVAAYPEAHPDSHGLKRDLEILKAKQDAGADRAI
TQFFFEPDHYLSFLDAARDAGIHIPIVPGIMLQPNFNGLKRISALCGATLPNWLHELYEG
LDDDAEQRELITANVAADLTMKLADKGVKDFHFYTLNKAGLSLSTCRLLGIKPTAKAA
>A0A2A9GSU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriaceae bacterium ES.041|TrEMBL
MPATENSKQTRISDKQTMIDPATAHTPGLLEGFSVEITGKDVPALIEAAPLLPRGTAVNI
TYLANEDAASRLRAAESVLSLGLHPVPHLSARRIRSAAELTETLAAYQQAGAADEVFLIG
GDPPSPEGPFPDALSLIETGVLEQHGVRSVGIAGYPEGHPKIADADLAEAMGLKLDAIAE
RGMAASIITQFGFDAEPVLNWIRGLRGRGIGAPVRVGVPGPAGIKRLLGYARRFGVASSA
GIAQKYGLSLTSLIGTAGPEKFLHALDDGLEPDIHGQVLLHFYTFGGVPATARWVHDHSE
EF
>A0A1X7KEK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia susongensis|TrEMBL
MNPIELSFEFFPPKTQDGVDKLRATRAQLVPLKPKFVSVTFGAGGSTQQGTLDTVIDMAK
EGLEAAPHLSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQARSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARQLESFGDDRESIRAFGLDV
VTDLCRRLIDAKVPGLHFYTLNAATATKAICERLGV
>A0A4U0VBE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Friedmanniomyces endolithicus|TrEMBL
MDKITDKLAALPPDSNYFSLEFFPPKTQHGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRRLVDDALEQAKALGVRNILALRGDPPRSDE
YRDDSGDQEALEADDSNKDFMWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSV
GHDMPYLVEKAAAGADFIMTQLFYDVEAYTRYERRLREHESGLFKTIPIIPGLMPVQSYQ
ILRRTTKLSHAALPPDILKRLEAVKGDDEAVKRVGVDIITEAVETMKSIPNPGPRGFHFY
TLNLEKVVTQILERSSLIPPATPIITMPYSNGGPDHAIAEEESDGFLIVERSKQNGNHRR
GSSVKNSQPRNRVVVSRDRASSTSSTHTSAFEAPEDEAGVPRDQINSRANTLAISQGEGT
VGREATWDDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPGSIGDISTIFRNH
LEGKIDAIPWSEEALQAETLTIKQHLLALVEKGWWSVASQPAVNGKRSNDPVFGWGPKNG
FVFQKPFVELFLPALDWEGLRVKLDADEQVTYFAGNAAGDFVSTDEHSVNPVTWGTFTGK
EIITPTIIEAVSFRSWVEEAFGIWAEWQRVYKPGSESSRLLERVRKDYWLVNIIHHGYLE
EHALWERLLGA
>A0A1T4WIF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecobacter debontii|TrEMBL
MHIRDIFARARRPTLSFEFFPPRSSEAVKDLQDSLLQLAPWRPDFVSVTYGAGGSTRDRT
QSWVKELGQSDVFDPIPHLTAVGHTEAEMMGILETYAAAGVSNLLALRGDPSPQVTQSGD
FQTAADLVRFIRRFNDRGLHPDPRGFGIGVACFPEGHPATPNRMLEMDYLKAKVDVGADW
MCTQVFFDNHDFHDFRARCELADIRIPILAGILPLTQKNSLSRMAELAAGSRYPAKLLRA
FQRAGDDTDCFQQVGIHHAVMQCTDLLDHNVAGIHFYTLNKAAFTLQVLRGLGSR
>A0A4S0RY91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M8A.F.Ca.ET.213.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHEVDAVIQEFTDMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEGEVA
GSAAA
>A0A7M3NSW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. uw30|TrEMBL
MALGTASIRPDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVGPDFVSV
TYGAGGXTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGEWVPHPQGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAAGCDTPIIPEIMPIASARTLERIPSLTNAGF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHPPQA
>A0A439QY52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGHKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVRRILTESTLTPAAHMTCVDADRDQVDTVIQEFAEMGVTRFVALRGDPAAGVGT
AYRPHRDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFSQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A8J8TFB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanomassiliicoccus intestinalis|TrEMBL
MSHLKDVLESGKFAVTAEISPPKSASCETIRKKAAMLKDCVDAVNLTDNQTAIVRISSFA
SSLACLQEGVEPILQMTCRDRNRIAMQSDVLGASAFGIHNVMCLSGDHQSFGNQKEAKNV
YDIDSIQQLMIFNKMRCEGRVWGGDELKEKPELFLGAAANPFADPFEFRVQRLAKKITAG
ADFIQTQAVFDVERFRDFMSSVCDRGLDKKVHILAGVMPLKSYNMAEHMKNNVSGISLPD
EMVSRMKSAADPKEEGLAICHETIEEIKKIKGVHGVHIMAISWESVVPRIIEDAELRD
>A0A1E3QHV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lipomyces starkeyi NRRL Y-11557|TrEMBL
GVQNLYDRIDRMKDLHPLFADVTWNAGGTSRQGVATTTEMIAKVNKAYGLPTCMHLTCTG
MSREAIDQALLEAYNGGCRCILALRGDPPLENEKWEATVGGFLYARDLVTYIREQYNDYF
EVGVAGYPEGHPEEHDHEVLIDHLKEKLDAGASFVITQMFYDVDHFLDWVDKCREKGITA
PIVPGIMPISNYASFVRRAKWCEINVPPEFMLALERVKDDDAAVREVGAELVSDMCKAII
EKGRIYHLHFYTMNLEKSTRVILERLGLLRN
>A0A1Q6X7P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_2_20CM_57_7|TrEMBL
MKIFDFNERLKDSILIADGAMGSMLHEAVGTQRCFDELNSTEPEAVFRVHQAYIEAGAQI
IETNTFGANRFKLAPLGLADEVQRLNSRGVKIAREARESAAREVLIAGSIGPLGLGVQSR
HPADHEILDIFHEQALALEERGVDFYILETFSYIEELLLAIDAIRSFSGLPIVAQLTYAE
EGTTYGDLRPANAAEQLKNKNVQVIGANCTLGPQALLPILQELAAVDGLRVSGMPNAGFP
KREGDRIVYPKSSPEYFALFAREAAALGVRILGGCCGTTPAHIRAMAEAVKSLRPAKAHA
VVHSVATMAKPASLSEREPESKFWKKLQAKQFALCVEIDPPKGLSLDRIFEQVGKVMASK
KVDAIDINSGAMARVGMDALIVAGALEARGVETVPHLTTRDQNIIGLQAALLGAWTVGGV
RNILAITGDPPSVGDYPEISGVYEVDSVGLVKVLHRLNQGTDWAGKTLGGETNFTIGVAL
NPVADDLDNEIERFHAKVEAGAHFAMTQPLFDPEHWHAFLKKLGGKPSIPVCIGIWPLNS
YKQALRLNNEVPGIVIPERLLKSMEAAGASARDCGFKVARDMLAWSRTELAGAYLIPPFK
RYEEILEIL
>A0A2H5X607|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR16|TrEMBL
MLQEGVLVADGAMGTMLQRLGVQAPYELANLMQPDAVRQVHRSYIEAGARLIETNTFGAN
RVKLATHGAGHLVREINLAAVRLAREAAGELPVIVAGAVGPVGKPLAPIGQIAPQEAGEA
FREQIEVLLEAGVDVILLETFTHLDELKIALEQLRTLDSEIPVIAQKAFIEDGETLASGL
PAQVARTLEEWGVDVIGANCVVGPQRMVGILQAMASATSLPLSVMPTPGLPQYQRGEVAF
EAQPDYFAQYGEQFARIGVNIIGGCCGTTPAHIRAVAERLQGVKPRVRRAPARVVEAVKP
EELPRAEPSQLAGKLGKKYVIAVELDLPRGLDVAKVLEGARSLKEHGVDAIDISDGARAR
LRMNPIAISHLIQEQVGIEVMMHFACRDRNLLAIQADLLGAHALGIRNILAVTGDPALIG
DYPTATSVFDIDSIGLVRILRRFNEGVDLAGNSIGVRTAFTIAVAYNPLAYDQHTEDERL
KRKAAEGAHLVYTQPIFDIAVLERAVEAVGKVGLPLLVGVLPLRSSRHAEFMHHEVPGVQ
IPDAIRKRLAELDDADARKYGLDVAREFALRAQKMTQGIYLMPPFGNHKVAEAVIDVLTG
>A0A5Q2VAL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia proteamaculans|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGGGKPDMYATDLVALLKDVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAA
>A0A836FKW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania martiniquensis|TrEMBL
MPALIVDAIAAEDANKWYTSYEFYPPRSEKAEDEFMKVQIPKFIRQSPVFLDLTWGAGGR
TSETTMRLCKDLQHAYPDIPINMHITCTNMPQGLIKETLDFAKTHGIRNILALRGDPPQG
EEYQANPDGFACAKDLVHYIRTRYGDYFCISVAGYPEGHPSRIAENGIISDEDSEKELEY
LKEKVDAGANVIITQLFYDASLYVKFVKRCREIGITVPILAGLLPIMTYAGFTRMVSLCK
TNVPRDVRKRVEELKENPEGLKEYGVEQCVQMIEHIRASGLDYHHLHFYTLNNSAQTFKI
LKRLNALVE
>A0A4Y7ZJ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychromonas sp. RZ5|TrEMBL
MNTEADYFTAKHLSQLNQNIGDIKHPIDVSFEFFPPASKKMENTLWDSIERLKTLKPKFV
SVTYGANSGTRDTTYEIIKDIKTKTGLVAAPHLTCIDASKEELREIAKEYWNNDIRSIVA
LRGDIPEGGARPHMYSTDLVKLLKEEADFDISVAAYPEKHPEASSAQFDLDVLKAKFDAG
ANRAITQFFFDAETYLRFRDKCVKQGIEGEIVAGILPVSNYKTLVKFAGMTNVHVPDWMH
KLYQGTENDEATRLLIGANQSMEMVKALTIEGVKDFHFYTLNRSDLSYAVCHSLGLRADN
AS
>W2T3U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Necator americanus|TrEMBL
IGHENKYVPLHERIDRRIKDKTPFFSLEFFPPKTANGVANFFTRLDRFNEGGPLFVDVTW
HLGSDPANMNKETSSSSIAAGCLDYCRVDTMLHMTCAQYSKEQTIKHLEQSKSVGLRNIL
ALRGDLPQIEIDGAPIYKYRALDMIRWIREEFGDYFTIACSGEEISVLFKLLRNLKFTDL
YLKLFPPYIADLLYLKSKCDAGAQFIITQLFFEAEVFEQFVRDCREIGITVPIIPGIMPI
MGYDSIRRIATLSQLTIPESILSDLEPIKHDDDAVRKYGTIKAIEMCRRILTNGSASSIH
LYTMNREGTCREILQELGLWHKRPMRALPWEPHGSNHPLRCKEDVRPIFWSARPKSYIYR
TRDWDDFPNGRWGNSSSPAFGDLQDYYLFHLKAQTKKEDLLKMYGEELLSFDDVKKVFVN
FISQSVNENGVKVTTLPWNEQEVGVQAETKLINEQLLWCNENGILTVNSQPSVNGAPSTD
PLVGWGKPGGYCYQKGTFDRMNGEATTPIAVTWGVFPGAEIAQPTVVDPLAFRAWKDEAY
DTWIKNWANIYPKDSVSRNVIQKVHDDFCLLNVVDNDFQKPVIIYEILKKVLKRTEERAA
SA
>A0A6M0CLK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spongiivirga citrea|TrEMBL
MKVTEHIKEAKGKTLFSFELIPPQKGRSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
RDGLLDKKLTRMRPGSVGICASITHKYDVDTIPHVLCGGFTKEETEYLLVDCHYLGIENV
MALRGDAMKEEKYFKPTNGGHCYASDLVEQIVNMNNGQFLHEVVETDNKSDFCIGVAGYP
EKHMEAPSMDADIRRLKQKVDAGADYVVTQMFFDNKRYFNFVENARKAGVTVPIIPGIKP
LAVKRHLQLLPQVFKLDMPDALVKEVEKCKTNTDARQVGVEFAIEQSKELMAAGVPVLHY
YSMGKSSNIQAIAKEVF
>A0A440GXH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MTGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDHGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHDEITETQVDMVK
TAH
>A0A433QQQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jimgerdemannia flammicorona|TrEMBL
MKVIDKIHKAEEEGRNFWSFEYFPPKTQQFREHSFEKLVRRRCGGAIAISVVALKKIGSG
PSPGVQNLYDRIERMYRLGPEFVDITWNAGGVTSQLSVEIVATAQSVYGLETMMHLTCTN
MPKEKIDVALKYRVVAWPQDEICGLIAACYVNRKPRIAGAKISLPSVVTPRGVLPTGRLW
KTASPTQSIWSSTSANSTATTLELPSPASILNTISSSHALTGHPEGHVDNRNLDEDIQFL
KQKVDAGADLIVTQLFYDIDIFLEYVRKCRAAGITVPILPGIFPIQSYNGLKRVISFDNN
VIPQKIWDDLEPIKDDDAAVKEYGIKLAIEHIQIMMDNGINGFHFYTFNLERSTRLILEG
LGFVPAPENVKPLPWNPSLSKKRAKENVRPIFWKNRIKSYIQRTESWDEFPNGRWGDSRS
PAFGELDGYGITLKYTPAECLAMWGTPATSDDISLLFAKFCRGEVAALPWSAQQLDPETD
AIRQRLAAINLLGYLTINSQPAVNGTKSADKLHGWGPKNGYVYQKAYLEFFVSPDKLDEL
IRKIERDPEVTYYAVNKQGDLRTNTKTDGPNAVTWGVFPGKEIIQPTVVEAVSFMAWKEE
AFELWAEWARIYPAADSVSAQLIKGIENSYYLINIVHNDFQDDHAIWRMFDLEIDGAISR
KLREHSIGAL
>A0A529H513|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
PFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILCGVGPLASAK
TAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAGVHVMAYRQE
EYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVKTAH
>A0A553BUH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium gawalongense|TrEMBL
MKVTQHIEDAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGIDN
VMALRGDAMKHEQSFVPKEGGNDFAVDLVKQINQLNCGKYLHDVMDIDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A2S1JXN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbulbifer sp. A4B17|TrEMBL
MKDSIRISFEFFPPKTPEGREKLYKTREALQAFNPEFFSVTYGAGGTTRETTSSIVTNMR
RDGISIAPHLSFGGDNEETILGLLNEYKEAGINRIVALRGDMPSGMGAVAQLVYANELVA
FIRRHTGDQFHLEVAAYPEIHPESNSYDDDIRYLKGKFEAGANSALTQYFYNPDSYFYFI
DQCEKAGIDAPIYPGIMPIANFANLVRFSRNCGAEIPRWLVKRMESFRNPEDIRKLGLEV
VTDLCETLLEGGAPGLHFYTMNQDAIVTKILKSLKL
>A0A529YBW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
VKRILNETTLTPAAHMTCVDAARDQVDAVVREFADMGVTRFVALRGDPAAGVGTAYRPHP
DGYANGAELVGAMKSAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRAITQFFF
DNDLYERYVERARRAGIYIPIVPGVLPVHNFTQVANFSARCGALVPAWLAERFEGLQNDP
QTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHEAEATGSAAA
>A0A4V6CRC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nakamurella flava|TrEMBL
MKTVKAFTQGLPDAGAAPIVPAATISANPLVTALRNASYEVLPFRGTADAVIACVPRDLP
VSITMTASKGIDATVELAVTLASAGYTVTPHLAARMFEDADQVSRTVDRLIAARATGAFV
VAGDLPTARGPFADSVSLIEHLDGLGRPFARIGVGGYPEGHARIEQAAIDTALQAKAAHA
TEVVTQLCFTPGTVVDWAREVHADGLTAPIRVGLPGAVTRQKLVRISAGLGLGQSARFLS
KQQNLLWRFLLPGGYRPDRLIRGLAPHLGTDGHGLSGFHFFTFNEIARTELWRAAWLRRV
EG
>A0A440HN40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MTGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHDEITETQVDMVK
TAH
>A0A442WX17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKREGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDKSGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A529XW69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MSARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRRPWKREIRRDDQIVAERLDHILYDEITETQVDMVK
TAH
>A0A530ZFQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A4Q1U0G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus chiayiensis|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNVALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDLEPVAHLPAAQLTRAQVDAELRGFQETGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQRGDFNVVAACYPEKHPESPDVVSDIQHLKEKVDAGASQLISQLFF
DNQVFYRFRERTELAGIHVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSDNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIATATKTIRNA
>A0A529LB34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
AAGAQFVQSQYCFDVPMFRSYMQKVRDLGYTEKCFILVGVGPLASAKTAKWIRSNVPGIH
IPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSGVHVMAYRQEEYVAEIVDESGVL
KGRQPWKREIRR
>A0A529MBB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
PPQVFLGCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTE
KLFLLCGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKE
IPGVAGIHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITET
QVDMVKTAH
>A0A5J5GKL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Histidinibacterium aquaticum|TrEMBL
MPAPTVSFEFFPPKSLEASFRLWDTVQTLSPLDPRFVSVTYGAGGTTRKLTHEAVTTIHK
TSGLPVAAHLTCVDATREETLEIARGYAVAGVTRVVALRGDPPKGSGGFRAHPGGFGSSV
ELIEALSGLGFEEIHVGAYPEAHPEAADSAACVDYLKRKIDAGATGAITQFFFEAETFLR
FRDACAAAGIEAPVVPGILPVENWTGVRKFAASCGTAIPPMLREAFDHAVRDGHADLLAR
AQATELCDELLEEGVEHLHFYTLNKPELTRDICHALGLSPKVALQEVA
>A0A0B5BB26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter pickeringii|TrEMBL
MTSPMTSPLHELLAADRFAVTAEISPPKGSDCGEFLEKARALRGTVDAINVTDNQGANMR
ISPLAPAALLVREGIEPILQLTCRDRNRLALQSELLAAAAFGVTNVLALTGDYITFGDHA
AAKPVFDLDAVQLLQAITTLNAGRDLAGTALHGVPRFYPGAAAAPEAEPFELTLAKLRKK
AAAGARFFQTQALFSPEKLIRFGEAVRPLGVKVIAGVILIKSAGMARYMNARIPGLTVPQ
ELVAELDDAPRPLETGTAIARRLVATLRPHCDGIHIMAMGKEELIPEILADLHRGD
>A0A3M4E5C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. atrofaciens|TrEMBL
MEASSPMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLN
TVLQLENEIKIPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGEL
RHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFN
ADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQ
SIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A7Z9SEL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIRDKVKKPQRPVVAYEILPPREKDGTLNSYAEIISSLLSQTHIDAINIPEVRDESGRG
DRPVTNQKRGEPREFGRLLQDIVGVEAIVNRVVVHEPFDAQMRWIEETNRDYEIENLIIV
GGESSKVEYPGPTVNEVLRSVSREYISNGGDIFCGGIAIPSREIESKNLIKKSEHGSEFF
TTQVLYDSSNIVKMIDHYQERCDDLNTFPRRLLLSFAPVSSQKNIDFLKWLGVEIPPETE
RYLQGRPGSMIERSLDVAIEVLNDTLNFITEKNLKVPIGLNVEHIMSYNFQSSVEMLQEL
ARIYREFCIKSVQYS
>W4GLI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces astaci|TrEMBL
MGKIIDRLTELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPREQLREILKNVRAAGIRNILALRGDPPIGSE
RWKAIPGGFQNAVELIRFIREEHGDWFCIAAAGYAEVHTEAWNNPNLPPSDQVRRVDMLR
LKEKQDAGADFIITQFFFDVDKLLQWIRDCRQVGITIPILPGYLPIQTYNSFLKFTNWCK
TSVPPQVEDALVTIKNDDSAVKKYGIQLAVDTCRKLLANNLSLHFYTMNLATTVRTVLEG
LHLIERERGLPWGAPITRSKDGTLEKSIEQVRPIFWSNRASSYIARTSEWDDFPNGRWGD
RTSPAYGELSEYYLAYKRPKVARDALWGRPQTEQDVWNVFVKFIEGSVKQLPWCEQGLSG
ESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPHLM
QRLVVALADYPNLSYHAFSANGTEYTNSPGPSVTAVTWGVFPGKEIIQPTVVDTASFAAW
KDEAFELWLSQWASAYETDSPSHQLIKRIFDSYVLVNVVDNDYTNEDSDIFKIFARVITE
SMTKDDLRQRVLELEGKNEKLHETVAKLKIIQAEANRELKDLHGDLSTSREENSRLKAQV
RELRSRLAMAEL
>A0A2E5U8Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISDKIKEYKKQKKVFYSFEYFPPKTDFGMDNLYSRIDRMSSLGPAYIDITWGAGGSTA
ERTLDMSKTIQKYFGLDVMMHLTCTNMSIKLIDEVLSEAKKSNISNILALRGDPAEGSNE
WRKENQAFNYGVDLVHYIRKNFGDTFFLAVGAYPETHQEQSDPDLDINYLKEKVDAGVDI
IVTQLFYDIDKFLLFRDKCLSKGIDIPIIPGIMPIHNYSRFRKFTQFCKVNIPENILKKL
EPIRNDDASVINFGIEQGADMCEKLVKEGVPGLHFYTLNLEHSVKEILNSIGLISDNKAN
RELPWRQSSDEIRKLSEDVRPIFWSNRPISYLTRTENWDDFPNGRWGDISSPTFGELNQY
HAIRAGSKSSEIRDKRKKIWGQPQSIKDISNVFMSFCKGDINTLPWCETKLAIESKQISN
ALIKLNESGYFTINSQPNVNGAPSDDAHFGWGAEGGRVYQKAYLEFFTSKENLDRLITKI
KKNNNISYQAVNLSEDLISNVRKDNVNVVTWGVFPGEKIKQPTIVDTRSFMIWKNEAFSL
WMNDWASIYEKDSISYSLLRNIYENYYLVNIVDNDFIKSNMIKQIIK
>A0A3A6CX13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium AF15-26LB|TrEMBL
MITEYIKKQGYFLFDGAFGTYYAQKYEDDQEPCELANLYHPQRVANIHREYIEAGADAVK
TNTFSANEQHLECSWDIIRRLLQEGYRIAKNAAQDQALVFADIGPIMEQKNVSLFTQYKR
IIDVFLEEGADCFLFETLLNTHALHEVSAYIKKRCPNATIVVSFAVTADGYSRQGIAMSK
LLQDCFADDDVDACGLNCVCGPMHMKRLLDTIDKTKKPILIMPNAGYPTILANRTYFRDS
STYFAKEMKQILEKGAALLGGCCGTTPVYIRKLKDALQERKEQMEAVIQSVPAQKKVNRR
DCNPLRRKLQKKQPVIAVEFDPPANCEIERFLNNAEFLKEAGVDAITIADCPIARARVDS
SLLACKLHRELDLEVIPHMTCRDRNINATKALLFGLQIEGIRNVLVVTGDPIPSEDRQEV
KGVFNFNSQILAGYIRDLNKTMFSEPFMIFAALNLNAVNFEAELMKAKRKVEQGVEGFLT
QPIHSHQALANLRRANAELDAYLLGGVLPIVSHRNAVYMNNEISGIEVDEEIVSLYEGTT
REEAQRLAVTISCQSVDEMRPYVDGYYLITPFNRVEIIADIVAHLHRQEEDASKKQ
>A0A7C7CM50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEKIANYKAQGKTFYSFEFFPPKTDYGLDNLYSRIDRMASFQPAYIDITWGAGGSTA
DKTLGMCKTIQKYFGLEVMMHLTCTNMPVSSIKKVLTEAKENGLSNILALRGDPPDGSSS
WKQHGFRCGADLVRYIRKGFGNYFFLGVGGYPDGHHEQSDLDIDISFLKEKVDAGSDIVV
TQLFYDVDKFLFFRDKCIKSNIKVPIIPGIMPIHNYARFLKFTQFCQVSIPDSVSTQLES
IKNDDSSVINYGIDQAAEMCQKLIENGVPGLHFYTLNLEHSVSAILKSLGFVSSRIRELP
WRQSASDDRKTSEDVRPIYWSNRPVSYLTRTENWDDFPNGRWGDIASPSFGELNQYHAIR
AGSKSDKVKARRKKMWGEPKSIKDITDVFVSFCKGKINSLPWCEIPLAIESQQISSDLIN
FNELGFFTINSQPKVNGAPSEDVEVGWGGPGGRVYQKAYLEFFTSRDKLDGLLKSMESTD
NISYQAINVDGDLITNLLENSVMAVTWGIFPGKEVIQPTIVDVRSFLIWKDEAFSLWIDD
WASIYKAKSESYV
>A0A1C9BYP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis Bt18247|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A3E5FS09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] spiroforme|TrEMBL
MKIIDLLHKRPTLSFEIFPPKNYDGDISSIYQTIDELSKLKPDFISVTYGAGGSTTKNTV
EIASKIKNDYNIEAVAHLSCIDASPKQLIKIIDALKENKIENILSLRGDYPKDYDPKNTY
HYFKYASELNEFITKNYPDTFCLSGACYPEVHQEATSLENDLDALKKKVDAGAQYLITQI
FFDNNYYYRLLREARIKGINVPIIAGIMPATNSKSLLKIAKLSGSNIPYNLSAMIERFKN
NPKAMKEVGINYAVYQIIDLITNGVEGIHIYTMNRPEIAKEIIARIDNILKEFIND
>A0A7Y9E839|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides panaciterrulae|TrEMBL
MDLQRRIRERRGEFLLFALTPPRRATSPEKSQEIADVTLERLQELDLDGLVLYDIDDESD
RNSEERPFPFLPTLDPAEYLSRHLNHWNTPVVVYRAVGKYDEAQLGSWLEAQEPDRVLSV
FVGPSSRDKPVATTLTRAQALGTKIKPDLLLGGVAIPERHTRNGDEHLRLLAKQAAGCAF
FVTQVVYDLNAAKNLVSDYRYECAARGQDPVPMVFTFSVCGSMKTLEFLRWLGVDVPRWI
QNDLRHADDTLDASFEQALATALELIAYCRRLGVPFGLNVESVSIRRTEIESSVNLAARL
QAELRRSE
>A0A8D0AK11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sander lucioperca|TrEMBL
MVNQVQRGDGSWQSCKSDSSGASNSSESSKESSRSSTPVLDVDRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGTGGPLFIDITWHPAGDPGSDKETSSLMIASTAV
NYCGLESILHLTCCNQTKEKISGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATD
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNY
GIKQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LKMWGDELMSEESVYEVFTCYITAQPNRSGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIAGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVN
YHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWKVIDDMFELLDATPEPKD
>A0A1C0BWT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium MTC7|TrEMBL
MHIDQILKKKKTLSFEIFPPKNKTGDISSIYHTVEALKDLHPDFISVTYGSGGSTIGKTL
EIADVIKNTYGIEPMAHLTSIVSTKEDVDAFCTCLKESHVDNILALRGDMPLDDSVVCPK
QFSYATDLITHIKKQFADDFCLAGACYPEVHQEADCFENDLKALKAKVDAGATFVITQIF
YDNNYYYRLVREARKMGIDVPILAGIMPALNAKQLLRTTRMCGCTVPFELSTRIEKYYYN
DEAMQEVGISYAVNQIIDLIANGVDGLHIYTMNKPEIAKNIFAQIPHILKDFYNYD
>H1VQF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum higginsianum (strain IMI 349063)|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTAMGLSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKDE
YRDTEDSDVDDIEDFVWAVDLVKYIRKNYGDYFCIGVAAYPEGHADESHPQGQSFEHDLP
YLVEKVQAGADFIMTQLFFDIKAYDKFENILREHPSGAFKDIILLPGLMPIQSYQMIKRT
TKLSHAKIPDNLMARLDAAKGDDEKVKQVGVDILSELVEQVKEVKNRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDPQLDNEEAVIDDGPGVPVSIPAVQLNGLSPITPAARALSGRRH
SSMGSSDPHNRIIVSSASNPAYEMTTAGLMASEPVNTRANTLAISEGVGAVGREATWDDF
PNGRWGDARSPAYGEIDGYGVSLHMSVTQAIRLWGTPKTIQDINNIFIRHIKGQLNAIPW
SEEELLPESNMIQQELLELNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVEL
FIPSSDWAGLVARLNEVTDNTICFYAANAAGDFVSSDSSGGLVLEGTEASTNAVTWGVFP
GKEIITPTIIEEVSFRAWAEEAFKIWGEWSKVYGKGSESEALLERIRTEYWLVNIIHHDY
VERDALWKLLSGXEGXYGDVWIA
>A0A423KVS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDAQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A252EDJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. T09|TrEMBL
MSDTQSTTVLNAFRRAAQAGEFLVTAEVAPPKGGDPTHMLQMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQHGIEPICQIACRDRNRIGLQSDLMGAHALGIRNILALTGDPVKA
GDHPDAKAVFDLEAVRLLQLIRKMNQGFDCNEKPLTDGSLDLFTGAAVDPQCASLSGLQS
RFERKIEAGAQFFQSQLITDFERLEKFMDTIAAGYKKPILAGIFLFKSAKNAQFINKCVP
GVNIPQHIIDRLAKAKHPLEEGVKIAAEQVQIARQLCHGVHMMAVKREDLIPEILDLAGV
APVNLVLTK
>A0A438MIV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea polychroma|TrEMBL
MTFELICEIEPPTKPDLKRVRHQIGTLSTIAHSFLIPDNHIGRATVSSVAVAHEVQAMGG
RGIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTSGNRTSDLTVRSMLEEARKF
SPDFRLGAAAGLRPLPAWKRTADFLFAQVSFSLEAQLRWREAHPVDKPVYAGVMVLASER
HARTLAAAIPDIAIPEDLVERVAADRMAGVEAACEQVLALRESGAFAGVHLIPVTRYRDV
ESRLATAL
>A0A450SC83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. FW|TrEMBL
MDDQGSKDRVFSFEFFPPRTPEGRDKLRATWQRLSELNPHFFSVTFGASGSDQSGTLETV
REIQRHSGIDTAPHLTCIGSSRVRIREILERYLATNIRRIVALRGDFPPDMTEMGEFRYA
NELVAFIRAETGNDFHIEVAAYPEFHPAAPSASMDLENFKRKVEAGADSAITQYFYNQDA
YLRFVDSCNRIGVRIPIVPGIMPITNYVSLARFSERCGAEIPRWLAKRLEGFGDNMDALQ
AFGIDVVTELCHRLLEAGAPGLHFYVLNRAEPVATIWKNLGLSKIP
>A0A4V3IRJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Hh14|TrEMBL
MAPTDPACIASAPPRVPFSFELYPPKTDAGATALHATIDRLAAAGPEFISVTYGANGSSR
GSSLEVLKYILHETHVDPMAHLTCVGSSHAEASALIREFLDAGVHSFLALRGDPPQGTRE
GDSFLGDLGSAAELVQLIHRVQAEKVPYRETVIPGLPRARRLRTDREKVRIGVAAFPNGH
PQSRSTSQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPVTS
PNRLRRILELSGEELPSELSIQLEIEPTDAGQREIGIDHAVRLGQELLAGGAPGLHLYAF
NQHDTVLSVLEGCGALPNGRTPTPQPHPTTAPTILRVASHPVKESA
>A0A564S7J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia obeum|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGIDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSVGMVRFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A7Y2SG85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PKU-MA01144|TrEMBL
MALGTASTRTDRARTVRELLATDKTSYSFEFWAPKTEKGERNLWNALRRVEAVQPSFVSV
TYGAGGSTRAGTVKATQQIAADTTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPDGVRYAAELVRLIKESGDFCVGVAAFPEMHPRSRDREADIGHFVD
KCRAGADYAITQMFFHVEDYLRLRDSVADAGCETPIIPEIMPVTSVKQIERFARLSNASF
PAALEERIRAVADDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQQS
>A0A7J6MQR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perkinsus chesapeaki|TrEMBL
MAKLIDKIEARWEHDRENGANGRLPFFSFEYFPPKTDMGVQNLYERLDRMAELGPMWIDV
TWGAGGAGSVANKTFEICKNALTYHGLDVMMHLTCTDQSAEEIDSVLERCKAAGIRNILA
LRGDAPTHSKEWRACQGGFAHAVDLVRHIRDSYGDYFCIAVAGYPEGHLEAESIDKDLMH
LKEKVDAGADLIITQLFYDTEVFFKFVEAVRNLGVTVPIFPGIMPIQSYSGFKKMTEFCK
TKVPRAIADQLEEVKGDDQKVKDLGVEICVAMCRIHELEVDLRYPCSQIMSYGVDHSHSS
GGLHFYTLNLESSVSRIIERLMMVDSHVATRALPWRPSKASSRQEENVRPIFWSNRQKSF
IQRTSSWDEFPNGRLGNQASAAYGDFELNFRSYSKETQDKVAADRRRMWGDRVPNGDHVR
RVFTSFIKGDVKRLPWCTESPTEETLFIQKQLIRLNQCNMLTINSQPRVNGALSTDPYVG
WGPAGGFVYQKAYVEFFCPEAQLEQIMQGLEREKYDSISYMAVTADGTQVKSNIPPQGRV
NAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWNEWMEVYPEDDHQSRQAGLVLSFIR
DHYFLCTVVDNDFVAGDLFSKLTKICTPVPWETLKIENPSESDGHEVPEVGSIHQLVPDY
IRVAGITGSDCRSVFATQQEEQCHYFVRPILTWSIPATIGYFHMSFKESQKDQCFVRKYS
DSVSAIMEGVGTDVAPSIQQLAPRSMLVCRIMDLNQIAHWLSESPMIPIVSDALHRIQDC
SEKPSPGYPH
>A0A854ZWK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pseudomycoides|TrEMBL
MKILDLVSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADIIQTN
TYGANEAKLRMYGLENQVTQINKAAVKLAKAAVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEKVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQLALHEAGATQNGN
DVNGILTQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPAHIEGMKRVIANVTPVTEKQIVQRQQVVH
IQTKRASTHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIEEIYEATKHLEKPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMDGHETQESAIEEGIRISQELINAAMKYFNGIYLITPFLKYEITENLVKYVK
EKQDVKEGIN
>H3AKG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Latimeria chalumnae|TrEMBL
MMVNPTHRSDSPAPTYKSDYGSGSGSSSMDDSSSRCSTPILDLDRLRDKMRRRMDSGDKW
FSLEFFPPRTVPGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSLMIASTALNY
CGLETVLHITCCNQTKEEISQHLNKASRLGLKNLMALRGDPVGEEWQEEEGGFNFASDLV
KHIRSEFDDYFDICVAGYPTGHPEAASYEEDLKHLKEKVDAGADFVVTQLFFRPETFLKF
VKDCRNIGITCPVLPGIFPIQGYHSLRQLAKLSKLQVPQEIVDVIEPIKDNDAAIRNYGI
ELAVEMCKVLLESGMVPGLHFYTLNREVATIEVLRCLGLWNEDPRRPLPWAVSAHPKRKE
EDVRPIFWSSRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKDQLLK
MWGEELTSEESVFEVFTHYISGEPNGAGHKVTCLPWNDDPLAPETNLLKEQLERVNKRGI
LTINSQPNINGSASTDPVVGWGPSGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVRDKNITNSTDLQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EEETPSRMIIQYIHDNYYLVNLVDNDFLLENCLWQVIEDMFELLAIPVEL
>A0A838UTG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ktedonobacterales bacterium|TrEMBL
TAAMHNVVTTSEPNHLYAIPMVSTEAHPRPDDAALLPAAGTPTRWQQRLDAGEFAVSVEL
DPPKGLSPAKVLAGAELLRGRGVEFINIADSPTARVRMSCIALARMLRDLLDIEPILHFT
TRDRNVMALQSDLLGAHVLGIRNILALTGDPLRAGEYPNLTGVWNTDSIGLVQVLRGMNE
GHDSGGSSLGGKASFYIGAALDVNVGDAPIDLAIEQARNKVATSVAGDPMTEQDLEFSRF
QAKIDAGAQYIMTQFIYDLEPLRQFHARFGQPSVPVVLGLSPLYSYKHAEFLHNEVRGIT
IPQAVRERMRAAGNRGREVGLEMAYELLTTARDEGLIQGCYLMAPYNRYDMVADLAASLL
GK
>A0A172YTU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NCu2D-2|TrEMBL
MSQLSQYLNQGQFCVLVEYLCTNNSLPVAQELAGFPALMTLADRVHADDDISPLEASRCY
SKSIDKILHFAGKDRDIQDFEKFLAQAQNEKIENLLLLTGDKLKNHHTGHDKYPRTRYLE
SVNAVLAAKQKGHFYIGVAFNPFKYAEAERDAQYLKLHKKLKVGADFIITQLGYDLTALK
KAVSFLKENHYSQHILACVMPLNLARANYMVKHKVAGIVITPHMLKILSQEKELGLKERS
YQRCALQILICKKMGFSGIHLSACHKPEDQALLAQFIEQYRSYDLPSLEKLWASLWQLKT
GKEFIPELSYFSKPAPSSQIIKYQQLHLLHDTLFDSKLGKGIGQIIFKAPFWNQKLAQKT
LMATEYLSKHSVVGCESCGECRLSDTLYICPETCPKGLANGPCGGTQLDRCEFGERECIH
SIKARLAKSVDQTEILKTKIIPTVSIEIRGTSSWQRWFTDDYEESKNIN
>A0A8J2JBV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium scirpi|TrEMBL
MHIKDMLSDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WIAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVADMCRKLLANGIHHLHFYTMNLAQATRMLLEELEWAPSAERP
LQHALPWKQSKGLRRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKTIQDIAELFVSYLENKVESLPWSEAPLTDEADEIRDGLIE
LNKRGLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPSVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPI
ANGAVDTEPIANGTTATAVAN
>A0A8J2JBV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium equiseti|TrEMBL
MHIKDMLSDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WIAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVADMCRKLLANGIHHLHFYTMNLAQATRMLLEELEWAPSAERP
LQHALPWKQSKGLRRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKTIQDIAELFVSYLENKVESLPWSEAPLTDEADEIRDGLIE
LNKRGLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPSVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPI
ANGAVDTEPIANGTTATAVAN
>A0A072DC13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ETR1|TrEMBL
MSQLSQYFAQNQFCCLVEYLPSKQEMLPVATQLAGFPVCMTLSDRVRSDDDIAPLIAAQS
YPQQIEKVVHYAGKGRDIHDFNLFLTQAKQHGQQNLLLLTGDKLKQHHDGRGSHARTRYL
ESVNAVIAAKQQGGFHIGVALNPFKYSQAEKQAQYLKLHKKLQAGADYIITQLGFDLVAL
KQAHEFLIEENYTQKILACVMPLTLARAKFMLKHNVAGIVITPHMLEVLAQEHDSDQTEN
TYLRCALQILICQHIGYAGVHLSACHKADEQAILTGYIEQYRHLDLKQCQQLWAQLWQLK
TGNELRPAVVEKSKLRNLQQKVKYQFLDTIHSTMFNSSLVKGLGAYIFSANFWNKALAAK
LLLQAEYLSKHFIVGCESCGQCRLAETLYICPETCPKGLANGPCGGTHLDRCEFGDRECI
HSVKARLAEEVDQIQVLKKQLIPTVPIEVRGTSSWKNWYVKQ
>A0A1C5ZKY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MRISELFGKGKCVFSFEVFPPKKNMPCDTIYSTLDSLKKLDPAFISVTYGAGGSDGNNIT
GKIAAHIKNDLGIESAAHLTCVSNTKQDIDIILEGLKADGIENILALRGDINPERPPKND
FRYASDLIRYIKSKGDFHISAACYPECHVEAPDMITDIKYLKEKVDAGAEHLMSQLFFDN
SHFYNFLEKARIADINVPIEAGIMPVVNKKQIERMVSMCGASLPVKFTRMMARYENNPEA
LRDAGIAYAIDQIVDLISSGADGIHLYTMNNPYVAEKISSAVSGLL
>A0A316W254|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceraceosorus guamensis|TrEMBL
MSAGTSSATGSQTIPAHVGSSNGALHSDSGTSSATKSIPSPHPSHIPSILSHHSSTRPAI
SLEFFPPKTSSGLQNLYARILRMKTQCGPSWMQVTWGAGGSTQNISMVLAGRVHKGLLRP
ADLDWTRWESPSSEAESRNRTLEEREIQAIIEAPANDELATECCLHLTCTNVSREALDVT
LKQARAIGIRNLLALRGDPPRGSEYWTPSDNRFQHAEDLVRYIRSGHGDWFSIGVAGYPE
GHTDSLTPSGEAEIPVLLSKQRAGASFIVTQLFYDVFLYHSWLAKARAAGITIPIIPGVM
PIQNYTSFRRITGLCKIQVPQELRRRLEDPTPEEIASAQSSGAAAFQGKEQRDKINVRND
DARVKEVGIEWSREMCRQMWRESVKSREERGAVEETLNPNHTAFHMCTLNLEKSVTRILH
DLSWAGPSQTTNKASTQEAAFAEDTSGTNGTNAADSGSATSVPKLHATLNDSLSVSAPAA
LWDEFTNGRYGDSRSPAFGEIDGYGVSLKVPPADALRVWRTPVTEGDISALFVAYLSGEI
QAIPWCDIPILNETQAIREELLGLNRAPSASLGEGDHSTIGKGWWTVGSQPAIDGVDSLE
PTFGFGPKGGYIFQKAFVEFFVDEEHMLALCRRVEEESDGLVGLLAGNKKGNFKTTLEAN
AVNAVTWGVFPGQEIAQSTIIEEESFKAWRDEAFEIWAEWELLFPQGSPTQRLLKSIGDN
KWLVTVIHHDFKDPGALWKFLGCGRSEHLE
>A0A017HQM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubellimicrobium mesophilum DSM 19309|TrEMBL
MSLLPFLRRKPEAPTTPSEATSRFLSGWSIEVMPRTAEKVEDFRAILPPGTRVYIAHIDG
TAIEDMVATAKRIAGQGFEVMPHFPARSIADRAMLADWIARYKGEAGVKEGLILAGGRAD
PAGEFTSSMELIETGLFDGFTRLHFAGHPEGNKDIDPDGSDRMVMEAMRWKQAFAARTDA
KVALATQFSFDAKPVIAWVDRLQAEGIDLPVHIGIAGPAKLQTLIKFAIACGVGPSLQVL
QKRALDVTKLLLPYEPDDVVDQLAAHKAENPAFGIEQVHIFPLGGISTAATWANTRTGQT
PALAANG
>A0A532DCJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MPEPKQRLRDVLERGEFAVTVEYNPPKGTNVSGLLDHARKLLGRVHGVNVTDCTAAVMRA
SSLSVCRLLYEMGHDPVMQMTCRDRNRIGMQSDLLGAHLLGIRNILCLTGDYPTVGDHKD
AKPVYDLDSVQVMQLAGGLNRGADYAGNTLDGTTEFHIGGAVTPEADPVGPMLVKLETKV
RAGARFTQTQGIYQPETFVTFMQAVRKLNVKLLAGILLLRSAKMAEFMNANIPGVAVPDE
MIAELRAAGPKHELDAGVEIAVRTIKTVRPHCDGVHIMAIKAVDRLPDILTKAGLS
>A0A410V132|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium guangdongense|TrEMBL
MSGAMTDLTTSATADGQNGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLEPKFVSVT
YGAGGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEIGVRHIVALRG
DPAGGIGTPYSSHPDGYQSSADLVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKA
KVDAGATRAITQVFFDNDFYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRNGTSV
PDWLAAKFEGLDNDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLG
IRANSAQKAA
>A0A2Z6AYL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio ferrophilus|TrEMBL
MRQNLITELSKRVILADGAMGSRLFDKGADPTTCFDLLNLDNPALVNAVHTEYLDAGAEV
LETNTFGANAIKLEAYGLAHKVSELNIRGAELARKAADTATGHVWVAGSMGPLGRMDEPL
PDHRVTEVYTEQAKALAEGGADVLIIETFPRLEMLLLALAAAKEATNLPVVTQMVFTGQG
GSLSGQSPQDSFAAMIQAGADVVGINCGMGPQGALKVLRRSGTPEKPLSVMPNAGFPEQS
GDRLLYNSSPEYFATAVMRCVSLGARLVGGCCGTGPAHIAALRKLLDERDASAPLRTLQT
TTATPSQAMPLADLPPSEFSRKLGTKKMVLVEIDPPKHLDITPALQGAEALANAGVDAIT
VAENPLAVPRLSNITLAGMIRRRTGAEVVVHLTGRDRNLVGTQSTVMGLAAQGLQNVLAV
TGDPPPAGSDDVIKGVFDLRSFELIELLERFNQGENRHGDPMRMRAGFAIGAAFNPNTKN
PALQVKRMERKIECGARYFLTQPVYTRGKVDEVVALTRHIDTPIHLGIMPLASARNAEFL
HNEFPGITIPDDIRARMHDAGDNGAQVGADIAWELIEYAWDHFAGIYIMPPFNRTAVALD
LVNRLRDKGLWTP
>R8NXH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VDM053|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTLKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKSHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6N9R6C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aromatoleum sp|TrEMBL
MTPQTSRLCSLEFFPPRTPEGIEKLRATRCQLAQLKPAFCSVTFGAGGSTREGTLATVLE
FRDGGLEAAPHLSCIGSSRESIREVLNEYRSHGIRHLIALRGDLPSGSADVGDLRYASDL
VAFIRQETGDWFHIDVAAYPEYHPQARSPGDDLAAFKRKIDAGANSAITQYFYNPQSYWH
FVDACAAQGIDVPIVPGIMPIGSFTKLARFSDACGAEIPRWMRKKLESYGDDTASIRAFG
LDVVTELADGLLARGAPGLHFYTLNQAALTTAIWQRLGL
>A0A849F0A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter sp|TrEMBL
MKVTDHILNAKGETLFSFELIPPVKGRNIKELYNNIDPLMEFNPPFIDVTTSREEYIYID
REGLLDKKLTRMRPGTVGICASIKHKYNVDTVPHVLCGGFTKEETEYLLIDCHYLGIENV
MALRGDARREEKYFEPTKGGHPYAVNLVKQIKDLNCGKYLHEVIETNDCANFCIGVAGYP
EKHLEAPSLQSDLKRLKQKIDAGADYVVTQMFFDNTKFFEFVKAARKIGISVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVDECKDNKAVRQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIQAIARGVF
>A0A839RRP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoyosella altamirensis|TrEMBL
MRPGRTPSIVERITADPRSTPFSVEFYPPRNEKEEQRLWRAVRTFEQLHPAFVSLTYGAG
GSTRDRTVRIAGQIATETTLLPVAHLTAVDHSISELRGLVGSYADRGIVNLLALRGDPPG
NPLGDWVMHPEGVEYAEELVRLIRELGDFHVGVASFPEGHYRAKDLDHDTYYLLNKLRAG
AEYSITQMFFEVEDYLRLRDRVSAADPVHGEKPIIPGLLPITSLRQVRKIVELSGSQIPS
HLEDRLARAAGSGPEEDRVEVRKVGIELATKMSERLIAEGAPCLHFCTLNFSRATQEVLT
NLGLAPVPA
>A0A0M8PSP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. FJAT-14222|TrEMBL
MGLLEKLKTHVLTADGAIGTVLYGYGLEYCHEEMNVHRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESRVQQFNEAAMTIAKRAAADGGQFVLGTIGGIRGIRKSDATLEEI
LATVEEQATVLLAGVPDGLLLETYYDFEELTATLTMLRAKTTLPIIAQVSMHEPGVLQNG
MSLNNALHELEALGADIVGVNCRLGPHHTIQAFEGVELPEKAFMSTYPNASLLDLEDGRV
VYESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVEEKHAKPEKVEV
VREAEPPNYEPLHVKVKRERSVIVELDTPRHLEIEGFIEGAQKLYEAGADVVMMADNSLA
SPRISNVAMGALLKETHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYSKEKIVEIYEATKHLETPIYLGIMPVTSYKSAEFLHHEVPGI
KLSDDALARMKACGDDKERATLEGIAIAKELVEVAAEYFNGIYLITPFLRYDMTLELMEF
IEQLDEQKKGVSING
>A0A7C4QTG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schlesneria paludicola|TrEMBL
MRIRDIYAAGRFGLSIEIFPPKTPDGDEALRETLTELAPYRPAFVSCTYGAGGSTSKRTV
EWCEEIQRRYRLTATAHFTCVGSSREQLLEWLHFAANAGIRNIMALRGDPPAGASQFQPP
VGGLNHAQELVALIRSHFPDMGIGVAGYPEKHPEAPSLEVDLAYLRQKVEAGADAVFTQL
FYENAHFFRFRELAHRAGIRVPIIPGIMPITEFARIQRITSLCGAFIPPELASRLESVRD
DKSAQFSLGVDYAIAQCRELLDQGVPGIHFYVLNKSAACRLILDALGMCPPGEP
>A0A1H1S552|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopseudomonas sabulinigri|TrEMBL
MNQTNNIPVSFEFFPTKTDAGHEKLIAAGHVLAAENPEFFSVTYGAGGSTRDRTRKTVLQ
LDSEVKVPTAPHLSCVGDSLDDLRNLLGEYREAGIKRIVALRGDLPSGMGQASGELRYAN
ELVEFIRRETGDHFTIEVAAYPEAHPQAAHFESDLKNFVRKAQAGADSAITQYFFNADCY
FHFVDRVRKAGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSDSICA
FGTEVISQMCERLVEGGAPSLHFYTLNQAEPSLDILRNLQGR
>A0A3A6MZ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulforudis sp|TrEMBL
MSIGPAAKVIEARTGSRLEKVLRAGHFAVTAEIGPPKGADGRRIQQLAALVKDYSDAQNL
TDNQTAVVRLCSLAAAVHVLNSGGEPVLQMTTRDRNRIALQSDLLGAASLGVRNVLCLSG
DHQRFGNHPEAKGVFDLDSVQLTATVRQMREERLFICGEEIKAPPRVFVGAVENPFAGPV
ELRVLRLGKKVMAGAEFIQTQVVYDVEGFARWMDTVCAAGWHKKTFILAGVTPPRSAGAL
RYMSRIPGMKVPEELIRRMEKASDKLREGQRIALEIINQVRAIAGVSGVHIMAINWEEAV
PEIVSMAGLYPRP
>A0A2A2CYP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albireticuli|TrEMBL
MALGTASTRTDHARTVRELLASGERSYSFEFAAPKSEKGERTLWNAIRRIEAVGPTFVSV
TYGAGGSSREGTVRVTERMATDTTLTPVAHLTAVNHSTAELRNIIGQYADVGIRNMLALR
GDPPGDPMGEWVRHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSDDWETDVRYFVD
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEDIPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A8I0P591|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces stelliscabiei|TrEMBL
MRDMLATGRTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSVTYGAGGSTRAGTVKA
TEQIAADTTLTPVAHLTAVSHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWIAHP
QGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSPDWDSDVARFVDKCRAGADYAITQMFF
QPESYLRLRDAVAKAGCETPVIPEVMPVTSVKMLERLPQLSNAAIPNALKERIVTAKDDP
AAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGPHHPSRA
>A0A0Q4R0H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Leaf72|TrEMBL
MNNKPDLRSAIAERILTGDGAMGTFLYQMGFPVGVSYEEFNILRPDVIENVHRRYYEAGA
QVIETNTFSANLEKLSIYGLEAEMEAINRAGVRIARAASGPDAYVVGAVGSIRAGKLKNT
RTVRVSDAYERQMAALLTEGVDGFMLETFYDLDEMLLALRIARKLTDIPVICQFAVEDVG
RTQDGVSLRQAFDQLTDEGADVVGFNCRSGPNGIMRAMKAIEGEATWPLSIFPNAGIPDY
VDGKYTYAATPEYFAASAREFADYGARIVGGCCGTTPEHVAAMAAALNHYSPQSGSQAAG
ETAVAEVETIVINEQPPVKLEIPDVRMPSEPNIVDTVRERHTVIVELDPPRDLDISKFMA
GAAALKACGTDAVTMADNSLAVTRMSNLALAALVQEKVGLRPLVHIACRDRNLIGTQSHL
MGLDALGIDHVLAVTGDPARFGDLPDSSSVYDFTSFEMIRMTKQLNEGIAFSGKPLKQKA
NFIVGAAFNPNVKHLDKAVQRLERKIKSGADYIMTQPVYDPALIKQVAEATKHLPIPVFI
GIMPLASGRNAEYLHNEVPGIQLSDEVRQRMAGLEGEAGRAEGVRIAKELLDEAVLHFKG
IYLITPFMFYDMAVQLTEYVWEKTGVHR
>A0A7C9F4Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagaceae bacterium SJW1-29|TrEMBL
MTKVTEYIQQAAGKPLFSIEIIPPLKGQNINQLLDSIDPLMEFKPPFVDVTYHREELIDK
HNSDGSVLRIPIRKRPGTVGICARLMERFRVDAVPHVICGGFTREETEDMLFDLHYLGID
NVLVLRGDPEKSAGVFTAKKGGHAYASDLIRQVCGMNQGVLLHEETQASPTNFCIGVAGY
PEKHFEATDYDTDFGYLKKKVEAGADYIVTQMFFDNQRYFKFVERCRAEGITVPIIPGLK
PLATKKQLTVLPRIFHLDMPEDLVRAAEQCETDQQVRQVGVEWGIQQCRELIEYGIPVLH
FYTMGKSDNVLQIARGVF
>A0A563E352|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leekyejoonella antrihumi|TrEMBL
MTVPRPQAIGPRGRSIPQMLEEDGPSFSFEFFPPKSDRAEALLWESIRRVEQLRPTFVSV
TYGAGGSTRDRTVRITGRIERETTLTTMAHLTCVGSSVSELRQVVGAYADAGIRNVLALR
GDPAGGLGAPWTPHRDGLDHADQLVSMVRSLGSFTVGVAAFPDTHPESADLAEDADAIVR
KADAGAQFAITQMVTDVDAYLRLRDLVAGRGRSIPIIPGLMPVTAYGQLERMTKLNGQPL
ATDVLDRIGAVKDDPDAVRETGVQICTEHATRLLQEGAPGLHFITMNRSTASQEVFDNLR
AVSTRH
>A0A2N0MPU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium MP-NPac-SRR3961935-G1|TrEMBL
MKITEGSFEATGHTSVICDFSPPRSGDAAVVGQAQIDADFISVAYNPGRAVRTNSAMLAA
AIQNSGKDAVFTLATRDMNKLALQTQLLGAQLLGVQNVVVVQGDPFGERDQTRVASVNDY
TPSGLIAAIAQMNQGQDFKESKLGQPTDFCIGATMDLGRGIEEEAQLAVRKVEAGAEFLI
TQPIFNVDHVARYRESFGYHAGKAGTVPIYLGLQILEKDGVLFSSVPESVRSELEDGRTG
VDIALELYRKFQKARLNNIYLMPPIKRGGARNYEAAKEFLGKIKKA
>A0A2G7GHV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroococcales cyanobacterium IPPAS B-1203|TrEMBL
MIAANRLQTLLNAGHFVVSAELTPPRHYKIKPLISKAEKIAAYVDVVHINDNALSQARLS
NVVAAHLIQQIGIEPVVQLTLRHKNRIALQSDLLGLAALGIRNVMILGGYPCSIGSDPDA
KEVNDISAIDAIAATHNLTTYGKMFNGDAIAPAPDFYIGTIAVPSTAPDKLDESMALLAA
KINRGARYIQLQATFDLTTMQQWMAEVVKRGWHKRVHFIGAVFPVSSWKGLEFLQTIPSF
IIPNDVVERIRSSDRKSESLKVTLELIQGIQAIEGIRGIHLRLIGSSDCSQIVELAGLRQ
AQRSTIT
>A0A248W7G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. 11515TR|TrEMBL
MSSRSESRSDGIRISFEFFPPKSEEAEQQLWNTVEELSDWDTEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLAAGVRRFVALRGDPPGGVGAAYQP
HPGGYANAAELVQALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRAAGIKIPVVPGIMPIQNLTQLKRFAGACGTNIPTWLDERFDGLDE
DVEERAKVAAEVAADQIQDLVRRGIHEFHLYTMNRSALVSAVLERLGLERKVDARAGAAA
>A0A0Q8X5F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root240|TrEMBL
MVTGAGRSLGELIREGGRSYSFEFFPPKDEAGEAQLWEAIRALEPYRPTFVSVTYGAGGS
TRDKTVAITGRIARETSLIPMAHLTCVGHTRDELESILDAYDAEGVAHVLALRGDPQEGP
RADWTPTDGGLNYAVELVELARARGSFRVGVAAFPEGHPSAESLDHDADVLVAKARAGAE
FAVTQMFFRASDYFGLVERVRARGVDMPILPGIMPILNLSAIRRQGELIGTSVPEEIVER
ISAHDGDAAAVRAEGIRIAAELCDELLAGGAPGLHFYTLNRSKATLEIFEALQITV
>A0A553CKS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium franklandianum|TrEMBL
MKVTQHIENANGKPLFSFEIVPPQKGSNIKDLYENIDPLMEFKPPFIDVTTSREEYVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGVDAIPHVLCGGFTKEETEYLLVDCHYLGIDNL
VALRGDPMKGEKYFEPTKGGNNYAVDLVKQIKAMNSGRFLHDTLPMQNAPDFCIGVAGYP
EKHIEAPSLEADLKRLKEKVDAGADYIVTQMFFDNQRYFKFVEAARAIGINVPIIPGIKP
VAVKRHLQLLPQVFWLDMPQDLIHSIEQAKDNTAVRQIGVEFAVQQSKELIEFGVPFVHY
YSMGKSDNIHQIASQVF
>A0A1I5IXM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohaesibacter marisflavi|TrEMBL
MSHNAEPSGRRSKETHKLNVSFEFFPPKTPKMEESLWASVERLAPLQPEFVSVTYGAGGS
TRERTHATVKRIIKEAGIPAAAHLTCVSATREEVDAVVRSYAEVGVTHIVALRGDPAAGV
GEKYVPHEGGYINAADLVAGIKRVGDFEVSVSAYPEKHPESPDFATDIEMLRQKVEAGAT
RAITQFFFDNDHYEAYVERVRRAGIFIPIVPGILPIHNFVQMAGFASRTGASVPQWLANR
FEGLEDDPETHRLVAAAVAAEQVENLRSRGVDDFHFYTMNRANLSYAICHMLGMRPVKA
>A0A2X2SM82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga ochracea|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
IMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPENLIKAVESCKNNNEVKQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>Q1N770|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. (strain SKA58)|TrEMBL
MTIDDRVPLYADLAGDARVSFEFFPPKTEKMEAQLWSAIETLAPLAPRFVSVTYGAGGST
RERTHNTVARIARETPLAAAAHLTCVAASTDEIDEIADAYWQAGVRHIVALRGDPPEQGG
RFEAHANGYAGAADLVEGLMKRHPFEISVSAYPEVHPDARDPQSDLDNLKSKLDAGATRA
ITQFFFEPDTYFRFMDKVRAAGIDAEIVPGIMPVGNFAAVQRMAAMCNTDVPAWMGRLFE
GLDDRPAARQLISATLAAELCRKLYEGGVRDFHFYTLNRAEHSYAICHLLGLRPKVTVEA
>A0A5M8P209|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Ordinivivax streblomastigis|TrEMBL
MSVIELLKNSTKTAFSFEILPPLKGNNFSKVCSIIDKLREFEPKYINITTHHSETVCREN
ADGSQQKINVRKRPGTVAIAGAIQNRYKIPAVPHIISKGFTKEETEYALIDLQYLGVTDL
LLLRGDAKKLEHDHVPPGKGHEHATDLIRQVAAFNQGVDLEGNTFDKPDTPFSFGVACYP
EKHEEAPSIESDMAFLKQKIATGAEYAVTQMFFNNQKYFDFVNRCREEGITVPIIPGIKP
IVFLNQLTVLPQIFGSDIPEAFAQALMKCKNDDEAKQVGIEWSIFQCKELIRKGVPSLHF
YTLMATDSVCQIAKSIY
>A0A7Z3YH21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas veronii Hm21|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A1M5VXX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium intestinale DSM 6191|TrEMBL
MKTKKKPLIFDGAMGTYYSIVSKNPSTKCELGNLYDRQTVLDIHKEYIDAGCGAIRTNTF
GANKEALESDFDVVKRVIKEGYEVAKEATKGTSVSVFADIGPIKELEGHELFKEYQEIVD
VFLDLGADNFIFETFSQEECLVDICKYIKSKNHKAFILVEFAVSPEGYTRLGNSGKKLID
KLSKITEIDALGFNCFSGPYHLLQYIKEFNIEDKTISIMPNSGYPTIINNRTFFDNSKEY
FASQMFEIAKLGVSILGGCCGTTPEYIKAMVLKLKELSLDDIVYDKISKPSEIKKSEVKN
KLIEKLDKGEKIIAVELDPPIDTEIDFFMSSAKKLKDQGVDAITIADCPIARARVDSSIL
ACKLKRELDITPIPHMTCRDRNINATKALLLGLNIEGVNNVLVVTGDPIPSAERDEVKGV
FSFNSSILANYITNLNETTFKSPFNVCGALNINARNFNAQMVQAKKKIENGITMFLTQPV
LTKEALENLKLARKELDVKILGGIIPVVSYRNACFMNNEISGINVSEEIIEMYKDISKEE
GTELAVKLSTQIAEEISEYVDGYYLITPFKRIDIISRIIENIKNK
>A0A6I6N6L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces broussonetiae|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVAHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSANWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCRTPVIPEVLPVTSVKMLERLPKLSNAVF
PDALKERILTAQDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A059LID2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicosporidium sp. ATCC 50920|TrEMBL
MAKIIDVLNERLKQDERFFSFEYFPPRTDDGLANLKPRLKRMQSYGPLFCDITWGAGGTT
SDLTMDIATYMQQEVGMRTMMHLTCTNMPVEKLSAALSAAKAAGIRNILALRGDPPAGQS
SFEAVEGGFASGLDLVRHIRQEHGDWFCIAVAGYPEAHPDVIVEDEAGMATNYESDLDYL
KRKVEAGADLIVTQLFYDVDQFLRWRDDVRSKGVTVPILPGIMPIVSAAGFKRMTSFCKT
RIPEEVRAALDACGDDEAAVKAFGVKLGSDMCRRLLAAEVPGLHMYTLNQETACKAILVE
LGLLREGEEGR
>A0A4S3MBT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Youngimonas vesicularis|TrEMBL
MTAPTVSFEFFPPQNLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRDLTRDAVATIHK
HSGLNVAAHLTCVNATKAETLAIADQFAAAGVNEIVALRGDPPKGTGAFQPHPEGFASSV
ELIEALAETGKFKLRVGAYPEKHPEAGSATADVEYLKRKFDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIIPGILPIENWKGARNFARRCGTDVPAWLDDAFEKAERDGRQDLLAT
ALATELCSDLIDGGVDSLHFYTLNRPELTRDVCHALGVAPKVSLENVA
>V8QT35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Advenella kashmirensis W13003|TrEMBL
MSSFSDEAFSLEFFPPRDQVSRERLVGTAKQLLAMHPRYVSVTFGAGGSTRDGTAETVSM
FSQLGCEAAPHLSCIGASRESLVQLLDQYKARGIRRIVALRGDLPSGMGNNDSDYRYASD
LVRLIREHAGDWFHIEVGAYPEMHPQADSPEQDLDHFVTKVSAGANSAITQYFFNADAYF
DFVDRAVQRGVTIPIVPGIMPITNSTQLLRFSQMCGAEVPRWIRLRLAQFGDDKASIRAF
GAEVVTQLCQKLIDGGVPGIHFYTLNNAEATLSVWKNLRY
>A0A3Q8CZ43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus nagelii|TrEMBL
MTNLAEKSSFSFEVFPPKTAVNNQKIFQTLDELHDLQPNFISVTSSNRTLNFENSTLKLA
DYVQNKLKVPGVVHLTARYFDRKQIDRILVELKFLGIKNILVIRGDLAPGRPPKKDFQHA
SDLMAYIKSKDANFRILGACYPESHPESSNKISDIHHLKEKVAAGCDCLLTQMFFSNETF
YQFQENCALADINVPLIAGIMPIVNRAQALHVLKQSECCLPKKFTQMLDRYQTDPTALKA
AGLAYAINQITDLVTNRVAGVHLYTMNQANVARYIYQATKSLFTIKNPV
>A0A544W3Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium hodleri|TrEMBL
MSCPSTTLPTRTRSSRRSRTTPSRSCSSRDVTARPTVESCPKRMEFGPCGGVRSDGQCEM
LPAPCVFDDAVPWSGAVAEPGPVSAPLILGDFSCSPFDAADVVATAAILARSCDAVLVGE
HQNRPDFPPTIMGGLLLETGVTPWITLSCRDRNRIVLEQELRGLAHVGVRTVFCVTGDGR
GYDVRPDVTQTFDLDGPRLVALADSLGMLAAVPETPTAPPVAARPLRLVYKQHAGARLAV
LNHVPSPSVAQEFVAAARAAGLTMPVVAGVAVFTDVVSAAVLQGLPGLELEQGVVDDVLA
ADDPVEAGIEAAVTEARNLLSIDGVEGINLSGSATARGTRFGAEVKAEVGARIRRELGR
>A0A3B9W9Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria sp|TrEMBL
MSAPLTAVHQDLTAAGAAPSGTSWLVRRPRRSTLVSFEVFPPRPTTDPDTVWRSIDAMAQ
AGPDFFSVTHGHSGGRGVSREALRHLRRTTRTPVMAHFTCGGTDRAGLERSVEHLLDDGV
RDLLALRGDPPLGAGEWVTPPGGIGRASELVRLIRDVERRRFGDGFRPGTRPLSVSVACY
PSPARGRDFEADLASLWEKQEAGADYAITQVLYEPEDYAAFLERARSEGIHIPVVAGLMP
LTNPKRLQRMTEITGVPVPERLTRFLTAGSPDELRHRGTAATLTLIDDLLDLGCAGFHLY
TFNRPDAALTILEHLRVRDAAREYRGRSPAA
>A0A4R2MXM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bisgaardia hudsonensis|TrEMBL
MSYAKEIDLLNQNIADLEGKINVSFEFFPPKNENMEVLLKDSIQRLKVLKPKFVSVTYGA
NSGERNRTHNIVKNIQSETGIIAAPHLTGIDATTDELRQIAQDYWESGIRHIVALRGDEP
AGYAKKPFYASDLVKLLKDVADFDISVAAYPEVHPEAKSAQADLLYLKKKIEAGANRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIIPGILPVSNFKQLDKMAKITNVKIPSWMRKMYEGL
DDDQTTRNLVGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGIRP
>A0A5E3ZZ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lawsonella clevelandensis|TrEMBL
MIWSCQFAGSSGEFVAGDEDTVPRFITMLSMLTTSASSVLDRIEESTSERIPFSVEFFPA
RTDEALEKLWASVRMFEQWGACFASMTYGAGGSNRDRMVDITARMRRETSLLPLAHLTAV
NHSRVELEQVLQAFVDNDIHNVLALRGDPPGDPLGVWRKHPEGVEFASELVEIIREKGGV
EIGVAAFPNGHFRAPTLDADTQFTLQKLRAGASFAVTQIFFEADAYLRLRDRLVEADKEI
GSRPLIPSIMPITSLKSAHRMVQLSGSRLPRSVEQRLDKAAGSGPEENVQAVSDLGIQMS
LEICERLIAEGVPALHFDTLNKVFPIADVLRGLGIISDAELEIAKNTR
>A0A836M000|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 1499986|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFELFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVK
TGEEFTPEIARFSRQPTSKQIIKYRQLHVMHETLFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKKTEILKEKLIPTVPIETRGTSSWKNWYLATEA
>A0A7X7HPP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MALFTPLRRWQPAFRPFSRQPAGRRLLALTERVVKGPLFGCRMCGNCLLQETAFICHMAC
PKGLRNGPCGGVNNGYCYVDPTRRCAWYLIYERSRRMHREHKLLEVLPPVDWDRAGTETW
GEVVRVARKAGFRKIFIPSAREGKKLGEVLEEKIFRPIRQPDWWQGDSEYHPPAVTEPQS
ALERELRSGRFVITAEVTPPLSAATGRLKEKIMLVKPWVAAVNFTDGSSAVPRMSSAACS
SVAASLGVDPVLQISARDNNRNSLQSLAIGANAMGAYNILCLSGDSPRVGPAPRSNMNIN
DLDSVQMLWILRRMRDEGIYLDGRQIKNRPRIFLGAAAAPYAMDPAMQAIRIRKKINAGA
QFLQTNLVFDPDSLDPWLEQMDKEGLLDKVFILAGVCPLKSLRLARYLNDNIPGVNVPEE
VMRRLADAGDHFAEESISITVENVEKLRGKRGVSGVHIMPLGWEEAIAQVIDRAGLMPGL
ITP
>A0A7C2ILB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacteraceae bacterium|TrEMBL
MAEQLPPSRAAEFRRSLERRALVADGAMGTMLYSRGVFINRCYDELNLSQPALIKEIHGE
YVRAGAEILETNTFGANRMRLAGYGLADKLEAINEAGVRLAREAAQGAAFVAGAIGPLGV
LIEPLGPTSFEEARQIFREQAEALVRAGVDLLILETFSDINELRQAILAAREAAGSEPVI
IAQVTIDDFGNLRDGTDTETYTRILEESPADVIGCNCSVGPKATLETIEKMLRHSRKPLS
AMPNAGLPARVEGRNIYLCSPEYMAQYARRFLWAGVKVIGGCCGTTPEHIRQVRAEVRSL
APVHRRIEAAVAEPEVKSRAREKVPLEKRSELGAKLASGRFVVFVEILPPRGVDASKEIA
GARLCARHGVDCINVPDGPRASARMSAQVTCHLIQQQAGIEAVLHFCCRDRNILGIQSEL
LGAYGLGIRNLICITGDPPRMGSYPEATAVFDVDSIGLTNIVNNLNQGLDIGGNPMGSQT
ALVIGVGANPGALNLEEELRRFEWKVQAGAEYVVTQPVFDLRLLEGFLRSIEGYRIPVIA
GIWPLTSYRNAEFMVNELRVPVPDAFLERMRRAESAEAARREGVAIAQEMVRLVRPMVQG
IQLSAPFGRYEMAVEVAEAVGAR
>A0A7J6UDX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perkinsus olseni|TrEMBL
MPIQSYSGFKKMTEFCKTKVPRAIADQLEQVKGDDQKVKDLGVEICVAMCSQIMSYGVDH
CHSSGGLHFYTLNLESSVSRIIERLMMVDSHVATRALPWRPSKASSRQEENVRPIFWSNR
QKSFIQRTSCWDEFPNGRLGNQASAAYGDFELNFRSYSKETQDKVAADRRRMWGDHVPNG
DHVRRVFTAFIKGEVKRLPWCTESPTEETLFIQKQLIRLNQCNMLTINSQPRVNGALSTD
PYVGWGPGGGFVYQKAYVEFFCPESQLEQLIRGIEGEKYESISYMAVTADGSK
>A0A6L8UDX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSVIEIIRKAKGTLFTFELLPPLKGHSIEKIYSTIDQLIEFGPAYINFTSHRNETVYHER
PDGLLEKRVVRKRPGTFALAAAVKYKYNIPVVPHVLCGGFTREETENVLIEMNFLGINDV
LALRGDPPRGSRSFIPEKNGHTYTWELVQQIVNMNNGKYLEATLEDTTPTSFCIGVAGYP
EKHFEAPNREADMDNLKHKVGMGASYIVTQMFFDNKKFFRFRDECRKAGIEVPIIAGLKP
VSALNDINLLPQTFHIDMPNELVKELQKCKTDRDAREVGIEWAAMQSKELIREGVPGIHY
YTLGRSDNVARIVRQSF
>A0A847IR28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MFKVSEKTFSFEFYPPRDEIAAVDFGLNIGQLIKLSPSFVSVTYGAGGSTQSRTFDLVDY
LKNRVGLNTVAHYTCVGSTRSRTLEDLKTLRKLGLQNFMLLRGDPEVGSKYGFIPCYDGF
ANATELITFAREFIDDCCIGGGAYPEVHPESPSAEIDMKNLKKKVDAGCDFLITQFFFDN
KRYFDFVARARKAGIKCRIIPGIIPLTKYAQLERFVNLSRASVPPAFLEQLESNRYNPDA
VYKAGMDFAIRQCRDLLMLGAPGLHFYTLNKSRATVEIYQTLMVR
>A0A328X216|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium lacus|TrEMBL
MKVTQHIENAQGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPSGLLQKKIVKKRPGTVGICAGIQNKYEVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKNEIYFRPEKEGNEYATELVTQIHNLNKGIYLDEDLQNSSCTNFCIGVSGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNQKFFDFVKKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSIELPDDLIMAVVKAKDNDEVKQIGIEWCTAQSKELVAAGIPVLH
YYSMGKAENIKAIAKEIF
>A0A2S4PR87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysiphe pulchra|TrEMBL
MEKITDKIAALPHGSNYFSLEFFPPKTSMGVSNLRTRLDRMSRALRPLFVTVTWGAGGST
ATNSLELAELCQRELGLTTCLHLTCTNSSLSVVDETLEKAYALGIRNILALRGDPPRKEY
MSTDMGIKETVKLEWAIDLVKYIKKKYGDYFCIGVAAYPEGHADGNDPDSQSLEHDLPYL
VEKVKAGADFIMTQLFFNTEAYDIFEKRLREHESGCFKMMPIIPGLMPIQSYQMIKRTVK
LTHVKMPPQILARLEATKGDDELSKKVGVDIVSEIISHIQHYPLPLLGRRGFHLYTLNLE
KAVSLILERTSLISPIHNNTPNYKSESEYVIVDNPITPSQASDKYSQSLKQIHCQNLDPF
ITDVDATIISSNSLGEVLPSDINFLSNDLTNRASTLAISEGAGSMGREATWDDFPNGRWG
DVRSPAYGEIDGYGVSLHVSIKQAIQLWGYPQSKDNITSMFVKHVNGSLVVIPWSDEGLY
RESDIIKDKLLMLNSRGWWTIASQPAINGIRSSDNVFGWGPRNGFVFQKAFVEFFIHSKD
WEPLKTKLETSSIAQDISWYASDAKGNFLSSDINKNLGSKSKDYSRNINAVTWGVFPGKE
IITPTIIEEVSFRTWAEEAFDVWDEWAKVYINGGPYPNDAIQEAAQRSHLLIKSLKEDVW
LVNIIHHGFIEKDLLWNFLLE
>A0A221R4R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinomonas sp. R1AF57|TrEMBL
MCIGKVEGGAPPRRRKESGTVSRTAPARNRSASLQLVNGFSLEMTGKDVPALLEAKDRIP
EGTRINVTFLGNEDLEMRVAAAKAVRDSGFIPIPHISARRLASQAQLEEFLGRLQEVGAS
EHVFAVGGDPATPEGPYEDSLSVIESGILPRYGVKEVGIGGYPEGHPDIPKPVLASALED
KAAALKQQGLGAVIITQFAFDIDPVVAWIDAVRSRGIDAPVRVGTPGPAGIKRLLGFARR
FGVGANAMIVKKYGFSLTNLMGDAGPDRFVDDLAAALAAPPQGEPAQENEAERLGGVGLH
FYTFGGLGATADWVRSFTAERS
>A0A270R375|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Alain-F2R5|TrEMBL
MALGTASTRTDRARTVRDILAAGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVELIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVGAAGCDTPVIPEIMPVTSVKMLERLPKLSNASF
PAELKERILAAKDDPAAVRSIGIDFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A3S4MS53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium gleum|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDIGRGKYLHNEEQVSDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYMEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAITQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A4P8G0Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio neocaledonicus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSAKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKATTGLVAAPHLTCIDATREELINIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFD
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRAVVGA
>A0A428J3K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. HMF5848|TrEMBL
MGFLEDLQSRILIGDGAMGTLLYSHGISSCFEERNLTNPDEVQRIHEAYINAGANVIQTN
TYGASYHKLARYGLEDKVYAINQTAVQLANAARANHDQDDTAHPLYVLGTIGGLRTLNKN
AINIEEIKRCVLQQLNALTSEPLDGILLETYYDWEEITTVLKLIRKQTDLPIVANISLHE
PGTLQNGLHVADALDQLTHLGANVVGLNCRLGPYYMIKSFEEVPLPTQPHTYLSVYPNAS
LPDYKDGQLVYETNEDYFAKSAIQLRAQGARLIGGCCGTTPKHIAALAQALHDLPPIQTK
NTKPRRIEIAVVEPIKTQQQPPLHEKAKTSKSIIVELDPPKKLNSTHKFMQGAKALQQAG
VDAITLADNSLASPRISNVAMATKLKQELNVNPLVHITCRDRNLIGLQSHIMGLHTLGIT
EVLAVTGDPSKIGDFPGATSVYDVSSFDLISLIKQFNEGLSYSGKPLGEKTNFSVAAAFN
PNVRYLDKAVQRLEKKIECGADYFITQPLYSETQIAQVHEATKHLDTPIYIGIMPLTSSR
NAEFIHHEVPGITLSDSIRAQMAAADDAEQEGIAIAKSLIDTAYEYFKGIYLITPFLKYN
MTVELTNYIHQKKEASIRG
>A0A4R8GMR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus oceanisediminis|TrEMBL
MSFLKKLKNEIIIADGAMGTLLYSYGTDSCFEELNLSQSEQIQHIHEAYIGAGAELIQTN
TYAANYLKLQRYGLEDSVKEINSAAARIAKKAAKGRAYVAGTIGGIRGFKPNMITLEEIK
RSFREQLYCLLLENVDGILLETYYDLEELETVLAIARKETDLPIIAQVSLQEAGVLQNQT
SIGDALTRLEGIGADVVGLNCRLGPHHMLKTLESVPLPKHAYLSAYPNASIPAYTDGKFH
YEGDAEYFRQSAIEFRNQGVRLLGGCCGTTPDHIKAFSDELKGLAPIEEKETRAINKVIV
SEKPSSSRELPPLHDIVRERPSVIVELDPPRKLDTSRFFEGAKALKEAGIDSITLADNSL
ASPRVCNSALGYLVKQQTGLRPLVHVTCRDRNIIGLQSHLMGLHALGLNDILAVTGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSFSGKDLGQKAAFSVAGAFNPNVRSLEKAVG
RLEKKIEHGADYFISQPVFSEEKLLEVHEAVKDLKAPVYIGLMPLTGSRNAEFLHNEVPG
IKISDSIRNRMASLKDDPAQAGAEGIAIAKSLIDAAAELFNGIYLITPFMRYEMTVELSN
YARETTERLSRRKQHA
>A0A662XKL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothophytophthora sp. Chile5|TrEMBL
MQLLLWHEALGSDDEQASEEELTARVLYSLDSSDELLPVGGGGWEAAASAERLLQSLHFV
QGLLAFVRLLRRSRAAAQAPPAWTQEWISVTLSRRRFFVLEVEPLIFLALKDHRHAYEAL
LRDVYRLFRLFHGSIDRNLRLLPSVSSRSVATATSDEKETESVPPHMKTHVDGMELLLDI
QTTRKRLRKLRLAIDAHTQNRPLDSSFQDDERRDAVVGRLEVEQQAVEAELQALIAQSPA
PHLHKKCANFFPTLLQALDVGGASSFSELQGLGYFPMDQPLFLALQSFVNNLHTELKSTE
AGAEIAETSALFFKGNLLWSSMEISMMHLLYKFLRLREERGMELGGCGNQQRERAGVRPP
AATERNNALWMEDAYEDTFLPVWSSKLSYTECAAVSQAENGRLHPRRAARSLHKQSPVSL
STFLAESTSSLGGIAKAGSSARVAAAVSTAAGSSPSVSAADSAFSSGSQRIATGGDHARS
KGAIKARASSVSFRNAGLLLQNGCFAKPSQLHQARTSSSASRGADGVWSPLVFPLGDVDA
SSEARATAATTEAGARRRVVVWHEADLTMVLILWSASTHQDLTGSAPEGPTMAILQRLEA
HLDKQQQFLMLAQRIFTRYHATFAPDMRYVGALHPLPPFLYLNRVNLAFKMQHVPRLLKS
KEDELFPLPTRLLPHYLPASTLALVNELHAELQAAASAGNRELCVRTRHAGWALAKKSQT
SRRELYVLFEPKVSSVQDLSGVRLFLSLRTPNAIRNLYHVLSSPIAFVKRSPPSIRSIRR
PPLAAAALSAAAPPAALPAAALPAMGKIIDSVLSAYRAPEDGRPTISFEFFPAKTNAGVF
NLLTRVEEMGLALQPTFVTLTWRSAFTDEQLWLRIGAHIQNEFQLDVLLHLTCHLPTQQL
KQILHKARAAGIRNILALRGDPPIGADRWTPVEGGLSNAVDLIRLIRQEHGDYFCVACAG
YAEVHTEAWNHPELPPSNEARALDLQRLRAKQDAGADFIITQFFFDVDNMIQWIADCKAA
GISIPILPGYLPIQNYSSFCKFTSWCKTRVPADVLSALDAIKNDDAAVRRYGTQLAVDTC
RRLVAAGVRSLHFYTMNLAATVTQVMEGLELLPARNQRDLPWQSTLQRSAAEGEQVRPIF
WSNRQASYIARTAAWDEFPNGRWGDRTSPAYGDLSEYYLAFKRPKLKRADLWGTPQSEQD
VWDVFVRFIDGHVKQLPWCEQALSLESAAIRENLQWLNANGFLTINSQPRVNGAPSSDPS
VGWGGADGVVFQKAYVELFVAPEKLAHLVTVMRRDYPQLSFHALNRRGDEHRNTPLHSVT
AVTWGVFPGTEIVQPTVVDSDSFAAWKDEAFELWQTQWASAYPADSQAREVIQHIHDSYF
LVNIVDNDYANDDADIFSIFTRIVTEAMDKEHLRARVLQLEARREKMFETLASFQALQEE
LGGELRAAHSELASARSTNLQLKEKVRQLQAQLALATL
>A0A497PIJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MGEAFSELMKKIKAGEFVYTGELEPHNLSTEIGDVVEWAKTLKGIGKITAANVTDNPQSF
SAMSSLAASFIIQRDSGLEMVYQLRTADKNRLALASDILAAAAFGLKNILALTGDHTHMG
NTPDAKPVFDLDSAQLVDLIHHMVYEGTDLSGNEVQGPRPEINIGVAGNPNQEPLEIEVL
KMERKAEVGADFIQTQVVFDVDIALTYLESIEHIGIPSFIGIFPPRSYGQAEFFDKFVSG
VTVPPEFLKTFKEFKAISDKAERKKKIDEFNIDYFVNFVKEIRKKKNCAGCHIMAVGYPD
VIAPIIEGAEK
>A0A7T1AN22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atribacter laminatus|TrEMBL
MSWLKQVLQSGHFAVTAEVGPPKGSDPQVIRKKCNLLKGFVDAVNITDNQTAIVRMSSFA
SSLVAQEQGIEPVMQMVTRDRNRIALQSDFLGACALGISNLLCLTGDHQSMGNHPQSKNV
YDIDSIQLLQIFKNIRDQKIFQNGEEVKGEMNIFLGAGESPYADPLEFRALRLAKKIAAG
AEFIQTQAIFDVEIFTRWMEEVCRLGLHKKSFILAGVIPVKSAKALRYMKNEVPGVVIPD
SLIERMEAATDQKAEGVEVCIETIQKVAKIEGVSGVHIMAIAWESIVPEIVQRSGLLPRP
AKGEITSS
>A0A8C6UYB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neogobius melanostomus|TrEMBL
MVNQVQRGDGTLSSRSDSSAASASGGDSSKESSRCSTPVLDADRTDRLRYKMRRRMESGD
HWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPSGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQSKDNISRHLSKAKHLGLKNIMALRGDPVGSDWEEEEEGFNYAVD
LVKHIRSEFDDYFDICVAGYPTGHPEAHSYKEDLIYLKEKVAAGADFVITQLFFRAETFL
KGVYAYLDQQCVCVQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIHQALEM
CRVLLDSGRVPGLHFYTLNREVATMEVLRQLGMWQEDPRRPMPWAVSAHPKRKVEDVRPI
FWGSRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLVFEVFTC
YIAAQPNRKGHKVMCLPWNDEPLAPETNMLKDELEKVNTRGVLTINSQPNINGKPSTDPI
VGWGPPGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPN
AVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYF
LVNLVDNDFPLDSCLWQVIEDMFELLQTGLDTGDVLGALNTGDGGASGGR
>G2PKI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda ruestringensis (strain DSM 13258 / CIP 107369 / LMG 19739 / B1)|TrEMBL
MKITDYIKRANGETLFSFEIVPPIKGKSIQELYKNIDPLMEFKPPFIDVTTSREEYIYKE
KDGLLDKKLTRTRPGTLGICASLKHKYNVDTVPHVLCGGFTKEETEYLLVDCQYLEIENV
MALRGDARKEEKYFTPTEGGHQYATELVKQIQDINEGNYLHDTIESTDLSSFCIGVAGYP
EKHMEAPSLQSDLKRLKQKVDLGADYVVTQMFFDNQKFFDFVKAAREMGIDVPIIPGIKP
IAVKRHLQLLPQVFSIDLPQDLIDAVEACNNNKEVRQVGVEWAIQQSKELREAGVPVLHY
YSMGKSDNVKAIAKEIF
>A0A519Y3L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKITEHIKNAKGKTLFSFELLPPVKGQSIDWIYKGIEPLLEFEPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADSSFVPTPGGHCYATDLIQHIKNHNAGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNTDFKYLKQKVDMGAGFIVTQMFFDNQKYFDFVNKCRENGINVPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNAEAKEIGTQAMIKQCQELIEFGAPVLHF
YTMGKPDQTKEIAKAVF
>A0A377JW18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter cinaedi|TrEMBL
MLEQLITKLKSNEPFLSVEVSPSLSSTIGQSVIDELESLRIADCFVCTDSPLARLKPSSI
LSSIKLQNALQKPLICTLSMRDRNSIALCGDILGANEFGLRSFLSLSGDGVKNGDCTGAK
GVFEESSLKLGRIIDDLNQGIAANGKTLKDSVETIYNFSVINSYANNTESLKKKMLKKLS
NSAVQGLFTQPVFSLEAARFLLESMESINKDLGQNCVMILGFFPVLSYKVALFLRDKLPG
VYIPDEWVQKLEKASIKGKEVERKIGLELSRELFKDLQALHNKFHFMSANKPSLLREFV
>A0A5K7XFC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacipirellula parvula|TrEMBL
MTIRDAYGSDRFGLSFELFPPKTAEGMTSLFQHVDALVKFEPSYITCTYGAGGSTQDRTL
DVISGVREKFGLPVATHLTCVGLTEPEIGAYLARALERGVENVVALRGDPPKGETEFKPT
AGGFSYANELVDFIRRDFPQMGIAVGGYPEKHQEAVSLAVDLENLKRKVDAGADAIITQL
FYNNDDYFRFRDACRNLGIEIPIVPGILPVTNLAQIQRIASLCGAKLPPRFVAALEQHAD
DPAGQFSAGVDFAIEQALGLLEGDIPGIHFYVLNKSEATSRVLSALPQFAED
>A0A519VXZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
FIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKPISTLSQLNVLPKIFHIDLPDNLADA
LSHAKSNAEAKEIGTEAMIKQCKELIEFGAPVLHFYTMGRPEQTKQIAKAIF
>A0A6I0CJY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia endophytica|TrEMBL
MGLLEDLQSKILIGDGAMGTLLHAHGIDNCFEELNITKPEDIFNIHKAYQKAGASVIQTN
TYGANFPKLKRYGAEEKVKDINIEGVRLAKKAVGDSGYVLGTIGGIRSFQKSIISLEEIK
RSFREQLFWLLSEDVDGLLFETFYDLEELKTVLEIARRETDKPIVTNVSLHEKGVLQDGI
PIVKALKILEELGADVVGTNCRQGPYHMLEILEEVPLLDKSFLSAYPNASLPQYVDGRLI
YETDPDYFYKTALAFKDQGVRLLGGCCGTTPSHIEAMAKALTNAVPITEKTVKEAPPIEV
LSQEIQAQPHLHEIVQENHSIIVELDPPKKLGVDKFLKGAHALQAAGIDALTLADNSLAS
PRISNLAMASLLKDQLKTRPLIHLTCRDRNLIGLQSHLMGMHTLGFNQILALTGDPSKIG
DFPGATSVYDLSSFDLIRLIKQFNEGVSFSGKPLGQKTNFSIAGAFNPNVRHLDRAVQRL
EKKVDCGADYFISQPIYSIEQLEDVYKATKSLKAPIYIGIMPLTGAKNARFLHHEVPGIK
LSENILTRMERIEHDKEQSAKEGILLAKELIDRAYELFNGLYLITPFMRYEMTVELANYI
KAKEIVSIERKI
>A0A7J9XEN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangiales bacterium|TrEMBL
MANDTATSTDRTDRHPKLGDVFASGGKSYSFEFFPPKTDKGELNLFHAIRELERLRPSFV
SVTYGAGGSSRDRTVSVTEKIATETTLTPLAHLTLVNHSVAELRQVIGQYANVGVRNVLA
LRGDPPGDPQAEWTKHPEGYAYAAELVRLVRASGDFSVGVAAFPEKHPRSPDMETDARFL
VDKFEAGAEFAITQMFFHVEDYLRLRDRVAAMGCDKPIVPGIMPVTNVAQIEKFAILSNA
VFPPDLAARLHEVEDDADAVRKIGVEYASDMCEQLLREDVPGLHFITLNKSTATREIYDE
LGLGSGAR
>A0A286RBG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermogutta terrifontis|TrEMBL
MADKQPFAEYLAQGVVVFDGAMGTEIYRHHVFTNRCFDELNLSDPKLIRKIHQSYCDAGA
EVLTTNTFGANRETLAKYGLAEQVRAINQAGAQIARQVADAADRPVYVAGSIGPLPTLPQ
NEEALWQMIWEQVDALLEGGVDFIIFETQPSRQALELCAAAMRERPGVPFILSAAVYEDG
ETASGETVQRLFAPLPEGCPEPLAWGLNCGSGPHGLLGAVEQAVRILRKPLVVQPNAGIP
KEVEHRRIYLCSPEYLAEYAKRFVNLGAAGVGGCCGTTPDHIRAICDAVKPLVRARIKPV
FVTPAETVELKTPVPLAERSRFAWRLVHKQWVTSVELVPPRGYDLRDIIEKSKMLHRHGV
DAVNIPDGPRASSRISPLITADRIQREAMIEVILHFCCRDRNLIGMQADLLACAACDIRN
ILFVTGDPPKLGNYPHATGVFDTDSIGMVGVQKRLNQGVDLGGQPIDPPTAAVIGVGLDP
TAIDQNRELDRFRRKVEAGAEFAITQPVFDPDALLRFLDKVQHYGIPIIAGIWPLASLRN
ATFLKNEVPGVVIPDWVMEKMASVTSREDQLKMGIEIARQAIERIRDRVAGVQVSAPFGK
IQVALEVIGA
>A0A258SCN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. 28-62-20|TrEMBL
MTISVSQLEEARRALEAPLFADLAGDANVSFEFFPPKTEKMEEALWETVKTLEPFGPRFV
SVTYGAGGSTRERTHATVARIQRDTSMGAAAHLTCVEASRDEIDAIADAYWQAGIRHIVA
LRGDAPGTTGFVPHPQGYTNAADLVAGLKRLHPFEISVAAYPENHPDSRDSADDLDNLKR
KLDAGATRGITQFFFEPETFFRFRDRLSAAGISAEMVPGIMPVTNFASIVRMSAMCGTAV
PAWLGRLFDGLDDHPTSRQLIAATLAAELCRKLYAGGVRDLHFYTLNRAELSFAICHLLG
LRARVGDRAAAA
>A0A167GFF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calocera viscosa (strain TUFC12733)|TrEMBL
MKLTEGISRHVASTSTPYYTLEFFPPRTDSGFENLLARLSRLSVVNPVGLSITWGAGGST
KQRSLDLAEATQRENPVTILHLTCTNMERAMLDDALDSAKARGVRNILALRGDPPRGEEY
WIPCDPQFQHASDLVKYIRQRHGDEFCIGVAAYPDGHSFDEDAELANLKTKVEAGADFII
TQLFYDADGFLIWLRKVREIGIEVPVLAGVMPIQSYASFLRMTKLCASRVPPSLIASLEP
IRHDDEAVKDFGVDFATDMIRTITSKKHNGPIVQGVHFCTLNLEKSTWRILDKLGWIGTT
SHVLDEGKNRLIQPDANAPPSSSSLLITPQDAASAVAPKDANDTGSIAPTTTTLPALPAN
QAATWDDFPNGRFGSADSAAFGVRDPYKNELGMTTSEVHRLWGQPETIADLNALFLKHLR
GHSPFSTTPWSPNPIAAETMLILPRLIEITSRGNWTVASQPAVDCVRSDDEVFGWGPKDG
FVFQKAFCEFFCEPNTLEQLKEKATIVDTVKFFAGNAKGEIVTNMALGESNAVTWGVFPG
KEVMQPTVIERAAFQAWAEEAFGIWSEWALFFPPASTTRQLLERVRDERWLVSVCHHDFK
NPESLWDFLLET
>A0A240EMR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio thalassae|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSTPTMEDTLWKSVHRLKTLNPKFVSVTY
GANSGERDRTHSIIKEIKSETGLVAAPHLTCIDASRDEIIDIAEDYWRNGIKNIVALRGD
IPAGGGQPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAGMNKVKVPGWMQKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQV
>A0A543VJR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cavourensis|TrEMBL
MLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSVTYGAGGSTRAGTVRATQQ
IAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWIEHPQGV
KYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFFRPE
DYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATVPEPLKERILAVKDDPAAV
RSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLGLHRQS
>H8GPB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomicrobium album BG8|TrEMBL
MNISFEIVPRTLEAFEKQYDFVQSLDKAINIINVPDIQHFDIRSWELATRIDPCKYRFIP
HFRAIDFKIESGELYRIIEQYELDNVLLVTGDPPEGLKRHYSNTNVIDLIRAVRRHFPKL
NIYAGFDPHRQGLQNECNYIQRKADAGVNGFFSQPFYDVRLIEIFAEHMDGLETYIGISP
VITEASQNYWEVKNHVKFPKNFSPEYDWNIEFANNVIASAAEKGLNVYFMPIKADLNKYF
QRINLFK
>A0A2T3MY43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium lipolyticum|TrEMBL
MGYSHASHLDSLNQNIADLNGDINVSFEFFPPSSEKMEETLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASRDELRTIARDYWNNGIRDIVALRGD
LPQQGVRPDMYAAELVELLRKEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNMTQAKRFALANNVKIPGWLEKQYQ
GLDDDLLSRQMVGASNAIDMVRILSREGVKDFHFYTLNRAELTYAICHTLGVKPGVEA
>A0A1Z9K118|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED183|TrEMBL
MAIRNDNNELLAVLSVRPVGGPLCLEIVMTDLKDAIAAAGQHWSIEVTPPGATKIDSFAE
ILAPDTTVNVTFLPGTDPMDTVDVAVRLRDDGMNPVPHIAARSVQSRDQLGSIVKEMASR
ANVDEVLVIGGGVDNPVGDFASSMEILETGVLQENGISRIGVSGHPEGSPDINDDQLAEA
LEWKNDFARREGLELYIETQFCFEADPVIAWENRIRARGNDLPIRIGIPGPATIKTLLRF
AQISGIGPSMRMITKQARNVTRLLTVQSPHTLITGLAEAMANDPESRLSHFHYYPFGGFA
RTEKWATAVAAGDFDLLPKGGFSVKEN
>A0A016A6L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis str. 2-F-2 #4|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A1Q2Z332|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces acidiscabies|TrEMBL
MNRLHSRHDVIVRADLVRAVRGLGYEVIPFAKTEQAVRDHVPTDVPLTVTASPAKGQDAT
IDLAVALAGHGYAVSPHLSAQQVRGHQHLAGLVGRCRDAGITGVFVVGGDRTATTTAFAD
ALALLRAVHELDHGFTDIGIGGHPEGHPDVSEQVLMQALADKAPLATHITTQIVFDPRAI
LAWIHRVRAYDIKLPIHVGLPGAVHRQKLLRVAGGLGLGESATFLKKQQTLLRRFFLPGG
YRPDALLSGLAPHLGEADDAVAGFHVFTFNDLAPTEAWRRRLLSDLT
>R6Z6I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:299|TrEMBL
MKIKDILAQGKPTLSFEVFPPKVQDNYDSVETAALKIAGLKPSFMSVTYGAGGGTSRYTV
DIASSIKAQGVNALAHLTCVSSTREEVQSVLRGLKERGIENVLALRGDIPEGGPLAHDYR
YASELIRDIREFDEDFCIGAACYPEGHVESANKTADIEHLREKVEAGCEFVTTQMFFDNN
ILYNYLYRIRERGITVPVIAGIMPVTNAKQIKRICQMSGTYLPARFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAEQIKTSLSEIL
>F2NGS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2)|TrEMBL
MRPMNKFQDALKSGKFAVTAGLTPPKGVNLAPFRQQVDALKDRVDAITISDNRGAHLAMS
SLAASALARQQGSEVICTLNCRDRNRLALAADLLGAYALGIENILPVSGDYLSFGDSPHA
MPVFDLDSVQVLEMARSLENGTAPGGQDLNGAPVFFLGGVANPEAKPLPPQVMKCLKKIR
ARADFLITLDVYDLQKLEAFAAQIDLVEARLIAGVRLIGPGDVARQASGNPPGNLIPPEI
MSEFQSLEESRAFDLGKRRAVEMIRCIKTRNLAHGVYLRADLHPEMIPEVIAAAEM
>A0A1G9CIH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas gudaonensis|TrEMBL
MSTQAHPLGISFEFFPPGTEAGRDKLLRTRDALAERRPRFFSVTYGAGGSTQARTRQIVQ
QVSEAGITTAPHLSCIGSEKSALRDLLHQYRDEGIDSLVALRGDLPSGMGGVGELRYANE
LVEFIRAETGDHFEIAVAAYPESHPQAPSFERDLENFARKMRAGANLAITQYFFTADAYF
HFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAF
GEEVVSRLCQRLLDGGAPGLHFYTLNQAEPALAILDNITV
>H8GMC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomicrobium album BG8|TrEMBL
MKSRYTHPKVLSFEFYPPKTEEGAASLKIVHEKLARLNPGFFSVTFGAGGSTREKTFETV
VEIQSKGIAAAPHLSCVASTRNGIRTILNDYRDKGIRKIVALRGDLPSGMLSAGEFRYAN
ELVEFIRKETGDAFEIHVAAYPEVHPQAPNADADFNNFKRKVEAGADAAITQYFYNAEAY
FYFRDRCERNGITIPIVPGIMPITQYSQLFRFSEMCGADIPRWLRKRLECLGDDRAAIQV
FGRDVVTELCRKLLEQEAPGLHFYTMNQSGPTLAILENLQFWPSAA
>A0A662K4B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MKYKSNLERVLVENNFAVTAEVGPPKGADADKVRVKGEILKGYADAFNVTDNQTAVVRLS
SLAGSVILLNMGLEPIMQVACRDRNRIAIQSDVLGAASLGIRNILFITGDHQSFGNHPGA
KGVYDLDSIQLIKVVKEMRDNGVFQSGDKILSGKPDVFIGGVANPFAEPYEFR
>A0A843A4D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MSSMNLIDIDSVQMLWLLRRMRDEGIYLDGRKMKNPPKLFLGAASSPFASDPCLQAIRDH
KKVNAGAQFFQTNLVFDANRLDTWLEQLDKRNILDKVYILIGIAPLKSFKVAEYLHTKVP
GVNLPDNILSRMEKAGEGAPEEGTQIALELIESIKNKKGVNGIHIMSLGWESVVRRIVTD
SGLRCY
>A0A2A4KIU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WZ.A104|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGQWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPADYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFPQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A484UTD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|plant metagenome|TrEMBL
MDVAVARRPPLHDCYSMEVSAKDIPALTAVAPRLPPASTISIPYLAGEGNAARLAAARAV
RELGFEPMPHISARRVASLAELQAFVARAAAEAGVERCFVIAGDPSTPKGPFPDSFSLID
TGVFERAGIKALGVGGHPEGHPVMSVADRWEVLERKCRGIEERGMAPSIVTQFVFDADVV
LTWLEALRARGIAHPVRVGVPGPAGVAVLARYAAMCGVGACASMLAKYGISIGKLLGTAG
PDRFVDRLAAGRTPAHGTVSLHFFPFGGIAQSVGWIEQYRATRKQNTR
>A0A7J4PBA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MEVIRQFKEILKEKEIPITYEIYSPRGYKVNPFIDSLSSFKDKIDAITVPDNPLATLKIS
PIAYAHLIKRSLKIDVIPHLTCRDRNSLALQSEILGAHLLEIRNLFVTTGDRAAESKGKK
EVREVNSIGLCKIIKLMNEGLSPSGEKFESSERTDFLVGGAIIFGRKNETNVLSKKVDAG
FDFFLSQIIYSAEEVINFFNQIEAQGFELNKPILFGLSPISSRKTLENILKMPSFKISAE
IREKLVKSTDIAETSRELCLEVAGQLKNELTPKYKIGFHLMPFGDDLLGERIIKEIR
>A0A2K3QCZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolypocladium capitatum|TrEMBL
MHIADMLTEAEQGRPSFSFEYFPPKTAQGVQNLYDRIDRMYNLGPKFIDITWGAGGRIAE
LTCEMVLQAQSVYGLETCMHLTCTDMGVDGVDDALNKAYKAGCTNILALRGDPPRDQEKW
TATDGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDVGATFI
VTQMFYDADNFVRWVGKVRERGITVPVIPGIMPIATYASFLRRANHMQCKVPGYWMDALE
PVKNDDVAVREIGKTLVADMCRKLLANGIFHLHFYTMNLAQATRMVLEELGWAPSAERPL
LPALPWKQSKGLGRRDEDVRPVFWRNRNKSYVLRTQDWDEFPNGRWGDARSPAFGELDAY
GIGLTGTNEANRKKWGEPTTVRDIANTFVRYLDQKIDSLPWSESPLTGEADAIRRDLVAL
NQRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPPPIFTDIIGRIESQPG
LSYYAVTKDGDLKTNAASDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDWA
HCFDSNTPSRALIEKIMNEWYLVNVVNNDFHDNRTLFELFKEIEVPDLDAPQAV
>A0A1F0S0L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC059E07|TrEMBL
MSPRLSASAPLDQISEDTPKRPQRTALSFEVIPPRHDADAKKIDRLLDTLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTEEELVGWIDTLVDAGVRGLLALR
GDLPEGGMPEGHLPHADSLVRLIRRWESARVARLAAGRLAVGVACYPNGHAESATADEDI
DVLLAKQRLGADFAITQLFFDAEEYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPPHVLDQLAAATSPEEEKEIGMQLTASLAKSVMNAGADGLHIYTHNNPDITTDLL
HRIGVTP
>G2J4N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogulbenkiania sp. (strain NH8B)|TrEMBL
MSIPFSLELYPPTSPQSARQLERALPRLAALGPEYFSVTYGAGGCTRERTLDLVGQLHEA
GHTVAPHLSGVGAERAEVAALCAHYRRLGVRRLFALRGDTPSGMGSRGDFAYASDLVRFI
REHSGDDFRIEVAAYPEVHPQAKSPAADLAALRVKQEAGANAAVTQYFFNTDAFLYLRDS
CHAAGITLPLVPGVLPLTRFRSTAQRAEARGIEMPRWIYRKMESLADDTAAVRAFGLDVT
ARQCERLVAEGVPALHFFSLNQIDAIEALHARLGLAGSAGTTAAPPN
>A0A3N9NKC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MQVIEAIKQSKDLMISLEITPPNKGQSIEELFQVIDPLTRYNPAFISVTYHQPQVVYEEK
NGLIYRIPKRKKPGTVGICAAVTNRYKVDTVPHFILGGFSKFETEDALIDLHFLGIENIF
AVRGDPPPGEKIFIPEKDGHKYASELVEQIHNMNEGFYLEQLENAQPTKFCIGVAGYPEK
HYESPNFEKDLYFLKQKVDKGAHYIITQMFFQFNVYRDFVEKARSAGIKVPILPGIKPIT
TLGQLSSLPRDFHITLPSELVESMEQARTPAESRKAGIAYVKKLCEQLIDFGVPGIHIYT
MGKGTATQDLLSLLFK
>F7JI89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 1_4_56FAA|TrEMBL
MKIIDRLLEDKIHISFEVFPPKTDAGYEKVRSATEQIAGLHPSYISVTYGAGGGTSKNTA
KIASYIRDELGVESLAHLTCASSTKAEVQTVIENLKALGIENILALRGDIPEGMVFPSED
RYHYAYELVEAIRRSGDFCIGAACYPEGHVENEHKEDDIKFLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAMLDRFGDHPK
AMEQAGIAYATDQIIDLLANGVKNIHIYSMNKPHIAAKIMENLSEVIQC
>A0A2E5GPW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leeuwenhoekiella sp|TrEMBL
MKITDHIKNANGKTLFSFELIPPRKGKSIQELYXXXDPLMXXKPPFIDVTTSREEFVYIE
KDGLLDKKVTRMRPGTIGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIHNL
MALRGDAMREEQYFKPTPGGHEYALGLVEQIAEMNKGRYLNGMVETSDCSDFCIGVAGYP
EKHLEAPSLKTDLKRLKQKVEAGAEYVVTQMFFDNKKYFEFVDLVRAEGIDIPIIPGIKP
IAVKRHLQLLPQVFKIDLPQELIDAVEACKTNTDVRQVGIEWAIQQSKELMDGGAPVLHY
YSMGKSDNIKAIASELF
>A0A3N5JKQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MLVKEILAQTTTTFSFEFFPPKTIAGWDGLFNNIRELRPLNPSWVSVTYGAGGSTRENTH
DLVLRISHETDLTVVPHLTCVNSTRNEIESIVDRYVNSGISNILALRGDAPRGETMWKPA
PDGFYFAADLIYFIKKHFPQMCIGVAGFPEGHPETLNRLLEMDYLKAKVDSGADYIVTQL
FFDNRDFYDFRERCELAGISVPVIAGIMPILSRQGMYRMVELAAGSRLPARLLKLILRAD
EEEYVAKAGIHWASEQVRDLIDSGARGIHFYTLNKSKATIQIYETLGVRHSQQFLRGR
>A0A3N9NMV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MTLKDKIASDRFIVCAEIGPPQSCDGDVIREKSKHFKGYVDAVNITDNQTAVVRLSSIAS
AKILLDEGLEPIMQMTCRDRNRLAIQSDLLGAAALGIHNVLCLTGDYPTFGDQPEAKGVF
DLDSIQLIATVAKMNSGFLLSDHEMNKAPEFLIGAAANPFAPPFEMRIIRLYKKVEAGAH
FIQTQPVFDLEIFTRWMERITYLGLHKKTAILAGVMAVKSAKTLILMQKKVPGVKIDKQY
IERMKAASDPEEEGVKIALEIIKILKEIKGVRGIHLMPYLWESITPTIVREAGLSIIS
>A0A373HQQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catenibacterium sp. AM22-15|TrEMBL
MKIIDLLNEDKVTLSFEVFPPKTSSKYENVLKAAEKIASLNPSFMSVTYGAGGGTSAHTV
ALAKDIHEKYDVEVMAHLTCVSSTREHVESMVEQFKENGIENIMALRGDIPKDGQVGEDY
QYACQLIKELKEKGDFCIGAACYPEGHVESPSIKEDIQHLKEKVEAGADFLTTQMFFDNN
VFYNFLYKIKEAGINVPVVAGIMPITNAKQVSRAVQMSGTSIIPYHFKMMVDAFGDNPEI
MKQAGIIYASEQIIDLIANGVKHIHVYTMNKPDIAEGIMNNISEILK
>A0A2N9DCI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. fragariae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWISKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A2N5M8K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peribacillus deserti|TrEMBL
MNFREEIQKRILVGEGAMGTQLYSHGIDACYEELNLLNPAQIESIHAAYVKAGADILQSN
TYGANYFKLKRYGLEDEVSRINRKGIQITRKAAAENTFVFGTIGATRSFRKSDLSLDEIK
RGFREQLYSLLIENPDGILLETYYDFEELTAVLAIAKRETSLPIISNVSLHEIGYLQNGM
HLAEALLRLEDAGADVVGVNCRLGPHHMVRSLEEVPIPNRSYLAVYPNASLPDLEDGRLV
YQANPEYFGQKALELRREGARIIGGCCGTTPHHIESVKKAIEGLEPILNKEIKSRKIEIN
VLQDPKPGKSLSRQAVEKRTILVELDPPKKLGIAKFIEGAEALRQAGADSVTLADNSLAT
PRISNISLGSLLKEKSNINPMIHITCRDRNLIGLQSHLMGLSTLGLNEVLVVTGDPSKIG
DFPGATSVYDLSSFDLIALINQFNEGLSYSGKPLGQKTNFNISAAFNPNVRYLHKAVERM
EKKISFGAQSFLTQPIYSEDQIDEVYEAVKHVKTPIFIGIMPLTSSRNAEFIHHEVPGIS
LPDSVRKAMASAGNDPVQAAKEGIAIAKALTEKAMEKFNGIYLITPFLRYELTAELTRHV
HRLDASRRVGVTVND
>A0A7K1FXF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nakamurella sp. YIM 132087|TrEMBL
MVTVRDRLAAPGPHFSVEFMPPRSDEEEASLWLAVRRLEPLQPAFVSVTYGAGGSRRDRT
IRITERIATETTLLPVAHLTAVGHSVAELRHVIGSYASVGVRNILALRGDPPGEDVTAEW
VKHPEGVEYAEELVALIKRLGPFSVGVAAYPDMHPRSPDPQSDIEFFAAKVRAGADYAIT
QMLFSAQDWVGLRDRAASVDVDIPLLPGIMPVTSYQRLMRICELSGQKVPDDLAARLLEV
KGDAAAGRAIGMEHAIDMARKLLDEGAPGLHFYTFNRSKATVEVLEALGWAPTPART
>A0A7W6YIV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MALKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTRAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKKIGDFEISVSAYPEKHPESHDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRPGRETKSAGA
AA
>A0A544X7I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus ottowii|TrEMBL
MKPDLRTVLNREIIIGDGAMGTFLYQLGFPVNTSYEELNITSPDVISDVHGQYLNAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIAKAAAGPEHYVVGAVGSICGGKRLNISK
LELSRNYEQQIDALLSEGVDGILCETFYSLDEMRIALHSVRKYSDIPVICQFAVDQVGRT
QDGFLMAEAFSTLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSMPLSVYPNAGLADYVD
GHYVYGASPEYFGECATSFVDLGTRLIGGCCGTTPDHIAAISKALNNVQPPPLASIEALS
TESIHVVEQTANEGGRGNGRHASDPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHVLK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYIMTQPVYDPELITAIAQETRHLEVPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGSEGRAMGVSIAKELLDTAMEHFNGIYLMTP
FMFYEMTAELTSYVWQKSGRALAPLFRL
>A0A3Q0E813|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carlito syrichta|TrEMBL
MDRQKARAFPAGHLCPSLGIWTRETGSVRLSVPPSISRSPAMVNEARGEGSISGGESSQD
SSRCSTPSPDPERHERLREKMRRRMEAGDKWFSLEFFPPRTGEGAVNLISRFDRMAAGGP
LFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRQEDITGHLYKAKQL
GLKNILALRGDPIGDQWEEEEGGFSYALDLVKHIRSEFGDYFDICVAGYPKGHPDAQSFE
ADLKHLKEKVSAGANFIITQLFFEAETFFHFVKACTAMGITCPILPGIFPIQGYNSLRQL
VKLSKLEVPQKIKDVIEPIKDNDDAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREVA
TTEVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGR
WGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFKVFVHYLSGESNQNGC
KVTCLPWNDEPLAAETSLMKEELLQVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVF
QKAYLEFFTARETVGALLHALKKYELRVNYHIVDVKGENITNAPALQPNAVTWGIFPGRE
IIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRKLIQHIHDNYFLVNLVDNEFPL
DNCLWQVLTDTLELLNKPAQNQTETEAP
>A0A6P7WLP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcaecilia unicolor|TrEMBL
MVNEAQSSDATSCSSADNSKESSRCSTPILDAERHERLRDKMRRRIDSGDKWFSLEFFPP
RTANGAVNLISRFDQMGAGGPLFIDVTWHPAGDPASDKETSSMIIANTAVNFCGLETVLH
ITCCNQSKDEITRHLHKAKRLGLKNLMALRGDPAGEEWEEEKEGFNYATDLVKHIRCEFD
DYFDICVAGYPKGHPDAESYEDDLRHLKEKVDAGADFIITQLFFRPETFLKFLKDCRAIG
ITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIKDVIEPIKDNDAAIRNYGIDLAVAMCQ
KIMESGMVHGLHFYTLNREVATVEVLRRLGIWKEDPRRPLPWAVSAHPKRRVEDVRPIFW
ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREVLLKMWGEELMS
EESVFEVFTHYISGEPNRNGYKVTCLPWNDDPLAPETNLMKDELQKVNRRGILTINSQPN
INGRPSADPVVGWGPSGGYVFQKAYLEFFTASENVSALLKILKKYGPRVNYQIVNVHGKN
ITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEEESPSRM
IIQYIHDNYYLVNLVDNDFPLENCLWQVLDDIFEELNCPTEQ
>F3PRK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fluxus YIT 12057|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGNGYHHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIHTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKEGITIPIIPGIKP
FKKLSQLSMLPKTFKVDLPEELTKEALKCKSDAEARQVGIEWCVQQCKELMAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A0F7D1F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia fonticola|TrEMBL
MSFYHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGGGKPEMYATDLVTLLKDVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPSAVVG
>A0A1B1CKH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MSQAIHLRDQSDVLDDFSVEVTTKDTAQLAAMSGAIPKGTIISIPFLSTESDADRIRAAK
MVRQAGYVPLPHIAARRLGSESMLSAMLSALVNDAQVSRLLLVAGDADPPKGPFLDTATI
LRSGILEQHGISNVSIAGHPEGHPVQNAAMLTSALLEKRLIMEAANIEWSIFTQFAFASE
PVLAWIGELRRLGIEVPIHIGIPGPASVRTLLKFAAVCGVSASTSVLKKYGLSITQLLSS
AGPDALVNEYATGLSNAEYGDVRLHFYPFGGLHKTVDWLQEYRTRHS
>K9AK79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei S18|TrEMBL
MSTTLTHADPTLDSTFRDVAQRPPIGPSLTGRPRLRTSASAPENALETDLDAERPRRLAL
SFEVIPPRSQAQAATLPALLAELDTLAPDYLAVTSSAKSGWLHGTADFIRLVTATTHLRP
LAHLACTAGTRAELTTWIHHLLGVGVRGFLAIRGDFPDGATAVPDGHLPHADALVHLLRE
IESANTARLAAGRLGIGVAAYPSGHPESSGSDEDLDVLAAKQRLGADFAITQLFFDPRAY
ADLRRRAELAGITIPLIPGVLPVTDPRRLHTMSRLSGLAVPDDLLRRFDGAADPATARRI
GLEMTAEHIAAILAGGADGLHIYTFNDQATTLDLLEMLDRLGIRLDSAPAPVPASAPQPS
>A0A4Q1UHQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MMIAPQSESREKAPLADLLSHYSIEMTSRDLQSLESITATLPRGCEVFVAHLPKEDIGLL
VRASAALRDAGFVPVPHIVARNVRNRLELDTMLARLSKEAGVRHALVLGGDRDDAAGAFG
SSLDLIETGLFQTYGIDRIAIACYPEGHPRIAGAVLDWALTAKVDAAARAGLDVLLVSQF
LFDPKPLLNFAGRLRERGVTAPLRVGIAGPASRTKLLKYALRCGVGASLRALRERSEIAR
NVLSGETPEELLMEIAAAQAAEPDLGISGVHFFTFGDPAQSIRWAEQQVDR
>I4L8L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas synxantha BG33R|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQSEPSLAVWNNLKLPR
>A0A1V6EMF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin090|TrEMBL
MKIPDILRNKKTLSFEIFPPKRQEDTFVLIENTIKELSDLGPDFISVTYGALGNTLSNSV
AIAKHIKQHTRSEALAHLTCVSSDKAQVDEICRELREANIKNILALRGDLPADPGMHHHD
FRHASDLTAYISQRYGADFAFAGACYPEKHPEAISMKEDIRHLKIKQDAGMDFFITQLFF
DNEAFYRFLLEARKAGITIPIIPGIMPVSNYKQLDGMIRVTGAAIPLQLRNYFDRYRYDK
QALEEIGIIFTSHQILDLIANDVDGIHLYSMNKSSFIKKLMANIAYVRSGFFAQE
>A0A1L3ZQ69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MDISGLKSEHRYRDVLERFSLEVTVKDASQLSDLSPDIPKGTLISVPYLSSDSGNVRISA
AKTIRQLGFEPMPHIAARRFGTEAELSDALSDFVREAQVTRLLILAGDLDPPKGAFRDTA
AILRSGVLQQHAIRHVAIAGHPEGHSSQSAGMLTEAISEKRRILEALDLEWSIFTQFTFS
AVPVLDWIIGVRSRGITVPIHVGIPGPASIRTLMRFASVCGVSASTAVLKKYGLSITQLL
SSAGPDVLVDDYAAAMIDGVYGDIRLHFYPFGGVRKSVEWIRGYRR
>A0A8B3JN18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. WCHEn090032|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A2N2D4A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-15|TrEMBL
MNNKFKESLLDKNTFSVTWELVPGRGAHEKLQENAILSAEQAAKDGRIHAITITDNPGGK
PALSAVYLGLEILKLGIEPLVHFTCKDKNRNQIESELYAMDRAGIRNLLVMTGDYPTNGF
KGRPKPVFDLDSIHVLDLIANMNKGLEIQESKGIAHQPSDFFAGSVVSPFKATEAELLVQ
YYKLKKKIANEAGFIVTQLGFDARKFHEVLQIIRNYNANIPVIGNIYILPFGAGKMMNSN
QLPGSVVTNKLLSELDQERTTEDKGVSARLLRAAKMYAFMKGMGFDGIHLGGHNIKYEQV
KYIIDKGEELSTEWMKLIPEFDYPQPNGFYFFEKDSNTGLNTNIAFNRTSLPVDLPVGLN
YRLMRFIHHLFFTPDKNLFPLMSRLYNGAKSPRKYTFEHILKVIGNGCKDCGDCALLDIA
YLCPMSGCPKNQRNGACGGSYDGWCEVFPNEKKCIWVKAYSILKAYNEEEQLENLYIPPV
NWDLYQTSAWYNYYTGRDHSAAIRKCK
>A0A6G2TR81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8366|TrEMBL
MALGTASTRTDRARTVRDMLAGGKTTYSFEFSAPKTPKGERNLWTALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNILAVR
GDPPGDPMGAWVAHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVEAGCDTPVIPEILPVTSVRMLERLPKLSNARF
PDVLKERILAAKDDPAAVRSIGIDFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHHPPRA
>A0A7G8G8B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. ROS8604|TrEMBL
MRSALQSSLEAGAVTITAEVMPPRGGDPSHALKMARALKGFVHAVNVTDGSRAVMRMSSL
AVARLLLDEGIEPVLQMACRDRNRIAIQSDLLGAHALGIRNLLCLTGDPVRAGDQPKARP
VNELESVRLLQQVTAFNRGDDPVKGDLADGPTDIFAGAAADPQCASWSGLVRRMERKKAA
GARFVQTQMVMDASVLERFCREIAEPMELPVLAGVFLLKSARNAGFINRMVPGACIPDTL
ITRLEAAADPAVEGIQIAAEQVQRYLGVAQGVHLMAIKAEERIPAILKQAGVSLPG
>A0A8F2UXX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Bovismorbificans str. Sal610|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0Q8LMZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. Root179|TrEMBL
MPSISFEFFPPKTDEQRAQLDRAAQLLKAHQPEYASVTFGAGGSTLSYTGDTVARLHAQH
GLPVAPHLSCMGGTKAEIAALLDGYRAAGYRRLVALRGDMPSGMATAGDFRYAAELVAFI
RAHCGDHFHIEVAAYPETHPQADDALRDLQHFKAKVDAGANGAITQYFFNPDAYFRFVDD
VRKLGVEVPIVPGIMPITNFSQLRRFSEMCGAEIPRWISKRMQAHGDDADAVRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRARATQAVLQQLS
>A0A367K0P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus azygosporus|TrEMBL
MKITTKIKKAEDEGRMFYSFEYFPPKTAMGVQNLYDRIERMQRFGPEFIDITWGAGGSSA
DLTTEIVATTQSVYGLETMMHLTCTNMPIEKIDKALEAAKRCGCQNILALRGDPPKGQLN
WESCENGFNYAIDLVRYIRDKYGDYFCIAVAGHPEGHVDNPDKDDDLLRLKQKVDAGADL
IVTQLFFDVDIFVDFVKRCRNIGIQCPIVPGLFPIQSYSSLSRVISFNKNHVPQKIWDDL
ETVKDDDQAVKDYGIDLTIQFIKRIKQETGISGFHIYTFNLERSSRLILEKLGLVPEQEY
VKPLPWNPSLTPTRGKENVRPIFWKHRTQSYIQRTESWDEFPNGRWGDARSPAFGEFDRW
GVSIKYPPEKQLAMWGTPESVDDIALLFAKYCKGKLEALPWSAQKLDPETDIIKQRLAAI
NFLGYLTINSQPAVNGARSSDPVYGWGPRNGYVYQKAYIEFFVSPEQLQVLIDKMSHEPE
ITYFAVNYKGELKTNTIYKEPNAVTWGVFPGKEIIQPTIVEETAFMAWKDEAFELWNEWA
RIYDRKSPSAEVILDIHDHWYLVNIVHNDFQDEDGIWRLFNLEIDGDLSRRLRRG
>A0A0D1DPP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ustilago maydis (strain 521 / FGSC 9021)|TrEMBL
MASDSAALSASLHGATASPSDPAHIATKIQAALTRDAPFWSFEFFPPKTSQGLANLYNRI
ARMHVNLEPSWIHVTWGAGGTTGGKSLELAGRIQKGKLDPDVELVQTEINHIGSGTQQHI
ENVKGGQEWEQERADPCDVCLHLTCTNVEKSSLDQTLDTAKRLGIKNILALRGDPPRGEE
YWIAADKRFQHATDLVRYIRQRHGNYFCIGVAGYPEGHADYVDRDVNRDLRYLKDKQDAG
AQYIITQLFYDVDRFLEWYRDCREIGITIPILPGIMPIQNYSSFRRMTNLCKVQVPQLIL
DALEPIKSDDAAVKEYGVSLSIHMVGRIFLETDVRGFHLCSLNLEKSIERILEGLGWKTD
VGAQQESDARLRGIPAHLHLENTKNQMLSDRTGTNTPKDFKVTTQEALARTLARTSSSYQ
VPETSTWDEFPNGRYGDSRSPAFGEMDGYGVSLKVPPQDALRIWGHPVSLTDISRIFGFY
LEEKISCIPWCDAPLMNETLQIRDHLLTLNRLAENASQSAGKGWWSVGSQPAVDGAPSTD
PIVGFGPPGGFVFQKSFVELFVSSSDKDRLVARIDALGASAPITYFAGNAKGDFQSNLGD
EEANTVTWAVFPGKEIVQSTIIERQSFEAWREEAFEIWAEWSLLFPKKSASRQLIDEIRE
ARWLVTVVHHDYKDKEALWQFLAE
>A0A258FHU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas subvibrioides|TrEMBL
MAATSLAPTLAQARALLLSPLGPVARAGGNANPVRVSFEFFPPKSDEAEANLWKAVRRLE
PLNPAFVSVTYGAGGSTRERTHRTVQRILTETTMKPAAHLTCVEASRDEVDQVIGEYKAI
GVDHIVALRGDPPGSAVSGGSGIGGVYEPRADGYANATELAQAIQRVGGFQTSVGVYPEK
HPESPSIEHDIDVLKAKVDAGATRALSQFFFDIDAFLRFRDRVRAAGVTIPLIPGIMPVS
NFAGLQRMSASCGASVPAWLAAHFEGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFY
TLNRADLVYAICRVLGVREQTAAA
>A0A0R1R5F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Levilactobacillus spicheri DSM 15429|TrEMBL
MSSIQPPTLSFEVFPPQSPADRAALLTTLDQLRGCHPAFVSVTYTNHQLDYEQATLGLAQ
TVQARVGCPVMVHLLAAYTSKTQVSRILADLESLGVTQILGLRGDLDPGQTPGADFPHAS
DLIRFIKARNPQFRLAGAGYPAGHPESPTREADLAHLQEKVAAGCDRVMTQVFYDNQQFD
RFRADCAARDITVPILAGILPILSRQQALRVETDFGARLPQPLRTRLDRVWDDPVAFRAV
GLDYAVEQINDLVAHGVAGIHLFTLNQASTVAAIYARTAALFEK
>A0A2N3LBV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira lohafexi|TrEMBL
MTAQKNTAAKNDLRVSFEFFPPKTEKMEETMWRSIHRLAPLSPSFVSVTYGAGGTTRDRT
HSSVTRIQGETGIPAAAHLTCVGHTKQEIEQIARKYWDEGIRSIVALRGDLPDAGDTYVP
TPGGYDYAADLVAGLKEIADFDISVSAYPEMHPDAPSADFEIDYLKRKLDAGANRAITQF
FFDNETYLRFRDKCQAAGITAPIVPGILPVTNFGSLLRFAKMCGADVPKRFHWRFDGLDD
DPDTRRMVAFHEAISQVEGLMKEGVTDFHFYTLNRAELTYAICHALGIRGTEQAVA
>A0A1B2UHA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. p52|TrEMBL
MDRLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERLGPAFVSMTYGAGGSTRDRTV
RVTGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWEK
HPEGLEYADELVRLVRELGDFHVGVASFPEGHHRSPDLDHDTRYLVQKLRAGAEYSITQM
FFDVEHYLRLRDRVVACDAEQGLKPIIPEIMPITSLRSARRSLELSGSHLPPVLEERLRR
AAGDGPEENRAAVREVGIEVATEMCERLISEGAPCLHFITLNFARATGEVLDRLGYELEA
PAAVQPA
>A0A1Q8ZIH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. 'hensonii'|TrEMBL
MPESAAPSPLSSFRSAVQSGQFLITAEACPPKGGDPTHMLEMARLLQGRVHAINITDGSR
AVLRMSSLAACVILQQHGIESICQVACRDRNRIGLQSDLMGAHALGIRNILALTGDPVKA
GDHPDAKAVFDLESVRLLQMIRQLNHGLDWNQKPLTDGATDLFVGAAIDPQLASWSSLQS
RFERKIEAGAQFFQSQLICDFDRLEKFMTQLATPAGKPVLAGIFLLKSAKNAQFINRCVP
GVNIPQPIIDRLEQAADPLQEGIAIAAEQVLMARQLCQGVHMMAVKREDLIPKILDLAGI
TL
>A0A1Y5RRU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudooctadecabacter jejudonensis|TrEMBL
MPAPSVSFEFFPPKSLPASFRLWDCVQTLAPLQPRFVSVTYGAGGTTRQLTHEAVEALTK
NADLPVAAHLTCVDATRAETLAIADTYKQAGVSHIVALRGDPPKGATSFQPNPDGFAGSI
ELTRALADRGFDVTVGAYPETHPDATSQQACIDHLKAKIDAGATRAITQFFFEADTFLRF
RDICVAAGIAAPIVPGILPVESWTGVQKFAALCGATIPALLHDAFDNAQGTDSADLMATA
HATELCDTLCSEGVEDLHFYTLNKPELTRDVCHALGVLPKMDLQNVA
>A0A085G3Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ewingella americana ATCC 33852|TrEMBL
MSFFHANQREALNQNLSELQGQFNVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERERTHSIIKGIKDRTGLEAAPHLTCVDASREELTQIAQDYWDSGIRHIVALRGD
LPPGGGIPELYATDLVQLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPHWMTRQFE
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGLATPL
SAAV
>A0A5C8KSJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. Alg18-2.2|TrEMBL
MRVSFEFFPPKTPDQHAQLARSAKRLAAHRPEFVSVTFGAGGSTLSYTPETVRRLKQEHG
LEAAPHLSCMGGSRAEIAQLLNEYRQQGCRRIVALRGDMPSGMARAGDFRYASDLVAFIR
AEHGDHFHVEVACYPETHPQADDALADLRHFKAKVDAGADGAITQYFYNADAYFRFVDEA
RALGVEVPIIPGIMPIANFSQLRRFSEQCGAEIPRWLAKRLQAHGDDRDAARELASDAVA
ALCRRLLDGGAPELHFYTLNLSRPTEAVLTRL
>A0A419T1S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacrimispora algidixylanolytica|TrEMBL
MKIKDILSQGKPTLSFEVFPPKTEDKYESVERAAAEIAKLDPAFMSVTYGAGGGTSKYTV
DIASALHHNHHVTALAHLTCVSSTKEKVREVLHELKEAGIDNVLALRGDIPVDGAVSKEY
SYASELIREIKEAGDFCIGAACYPEGHVESASKTIDMDYLKEKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVVAGIMPVTNVRQIIRSCQLSGTYLPSRFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANGVNAIHVYSMNNPEIAYKIKENLSEIL
>A0A0S4KPW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrospira inopinata|TrEMBL
MTREPRRLKDVLDQGRFAITVEYNPPKGTNITGILENAKQLLGRIHGVNVTDNTAAVVRA
GSLPVCRLLYEMGHDPVMQLTCRDRNRIAMQSDLLGAHMLGIRNVLCLTGDYPTVGDHKD
AKPVYDLDSVQVMQMVRGLNEGHDLVGNKLDGTTSFAIGAAVTPEAELVGPVLAKFEVKV
KAGAEFFQTQAIYNPEVFAGFMKAVRPYKVKVLAGILLLRNAKMAEYMNANIPGMSVPQD
MIDALRHAGDKSEEVGVEIAVETIKAVRPHCDGVHIMALKGVHRIGEILTKAQIG
>A0A852TUD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spinactinospora alkalitolerans|TrEMBL
MPGLAELLGAATASRPVITAELPAVDGGGPDAVRAHVTRLAPHVDAINATDNPAAHAHAA
NLAIAIAVRELGVEPVLQVVCRDKNRLALQADIVGAALHGITSICCLTGDDVTAGDEPEA
KRVFDLDAPQLIRTAATLARGSYLSGRPLTPAPPLFIGAVENPAAPPFEYRVRRGLKKAA
AGARFLQLQICYRPERLADFAELAERTGLTRKVALLPTICLVRGAQALRFMDANVPGVYV
PADLIERVERASDQREAAYRIALEQARHALAQPGVRGLHIADFRRDDTLARLRADLGLPA
VRPLPDGSSLAV
>A0A7K2AJG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MNGVGPATRSAIAGVLDNARFEIIPLKNAVAQAAHLPSGSVITVTASPNKGMEATMDLAA
ELAETGFDAIPHLSARLHRDRAHLEATLDRAAELGLRRAFVVGGDHLHPGEFFDGISLLR
AMEEIGHPFDEVGIPAYPEGHPLIPDAKLDQALSEKQPYAHHLATQMCFDAQAILSFLSG
ARRRRVELPVLLGVPGVGGRLKLLEISARIGVGDSVRFLTKNARVVTRLLGPGGYDPGEL
LEDLGDSLVDPLLRIEGLHIYTFNRCEATEAWRQEYLEALR
>A0A7V7CRG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTGSQLKRVLENGEFAVTAECGPPKGADPEIVRKKGELLRGNVDAVNVTDNQTAIVRMS
SLAACALLKQAGLEPVLQMVVRDRNRIALQSDVLGASALGIRNLLCLSGDHQVFGNQPDA
IGVFDLDSMQFLQVVKGMRDKGVILGNDALQTSPDLFIGAAANPFADPKEFRVVRLAKKI
KAGADFIQTQCIYNLDRFEAWLS
>A0A831NE54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGFKEDLRSGKFVITAEICPPRGTEAAPFIEKARLLKGRISAANVTDNQRAVMRLSSLAC
SILLMKEGLEPVFQMTCRDRNRLAMQSDLLGAWVLGVRNVLALTGDHVSAGDHREAKAVF
DLDSVQLVSMITTLNSGKNMNGVELRGGTDFFIGAVVAPEASPWEPEEIKFEKKVEAGAR
FFQTQAIFDMDKFKRFFDGAAKTEASILGGILLLKSAKMANYLNANVPGVHVPQGLIDEL
EGAPDQLEKGIEIASRQVRELKKFCHGAHIMAIGQEESVVRIIEEA
>A0A2E2NNT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
METFREALASRIILFDGAMGTEIYKRGVFINRSYDEVNLTAPDIVQDIHSAYITAGADVV
TANSFGANRLRLLPFGLEDKHDEINATAVRLARAAAKGNAFVAGSIGPIGTQLTPIGRVS
PGEAYQAFKEQAEVLEAEGVDLYILETFAHLPELWQAVRAVRSISTKPIVACLTFPHTGV
DGSALGDVLPEQAIQTMQSWNVDAIGTNCSNGPRGVLDIVERIIHHSALPIAAMPNAGLP
QMVEGRTLYLTGPEYMAEYARRLAQTGVRIIGGCCGTDPETIKEIRNFLRSIEPMGTATT
VVTETHTTAEVDQGEEPVPAAERSEFARRLLGGKFCISVELDPPKGVSAERAVNGAAMLY
EAGIDVVNIADGPRAVARMGPSALSHLVQRKTPELETVVHYCCRDRNLLGMQMDLMGSHA
VGLRNVLAVTGDPPKMGTYPDATAVFDIDSIGLINFIQHMNRGIDFSGKPIGGQTSLFVG
AGCNPGAIDVDFEAERYGRKVEAGAEFFFSQPCFDLELLETFLEKTKAWSHIPFMVGIMP
LVSARNADFLHNEVPGMQIPEPIRKAIHAAPSKEEQRKTGVEIAHKTLKALRHHPRVQGA
YIFPPFGSYKAVLKVVDGLLDDWVAPKS
>A0A7V5IFI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSNLEKILNKGIFAVTGELGPPRGADINAIREKAKHLKGMVDAVNITDNQTAVVRMA
SWAASLIALQEGLEPNYQMVCRDRNRIAMQSDILGAYTLGIRNILCLSGDHPVFGDHPFT
RKVFDIDSMQLIAMVKKMRDEGKFLNGEEITHPPRMFIGAAANPFGDPHEFRVLRLAKKI
AAGADFIQTQSIYNMKRFREWLNQANDMGLTEKVYILAGVTPMKSLGMARYMQKNVPGMD
VPDEVIKRLEGVEKKKQAAEGIKMCCEQIEELKTMKGVAGVHLMAIEWEHRVPEIVEQAK
LLPRPNPQDLD
>A0A7C1W6B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga aminisulfidivorans|TrEMBL
MSKKLTVSCEFFPPKTDKGAANLRRVRDALLPLKPEFYSVTFGAGGSTQDNTFDAVTDIQ
RHAQTTHVDAAPHLSCVGSTAEKLRALLNAYQENNIHRIVALRGDLPSGMRDPGDFRYAN
ELVEFIRKETGDYFTIEVAAYPEVHPQAQSAEVDLENFKRKVDAGANSAITQYFYNIDAY
RYFVDNCQSNGIDIPIIPGIMPINNYAQLARFSSGCGAEIPRWLRKRLESFYDDTESMKA
FTLDFLTDFTQQLIDCGVPGLHFYSMNKVEPTLTICERLGLTQHT
>A0A7Y9MSR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. JAI131|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKTYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQASDALSDLRHFKAKVDAGADGAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQALGDDAEAIREFGADLV
AALCERLLAGGAPSLHFYTLNLAKPTVGVLSRLA
>A0A7C3EFZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRICHLLQQKRPVFSFEFFPPKTPQGEAALFRTIEALRPLAPGFVSVTYGAGGSTREKTL
DWVARIKHELGIEAMAHLTCVGSNRDEMRAMLQRIDDLGIENVLALRGDPPRDQPGFQPI
PDGFAHASDLVRFIRTEGFSFCLGGAAYPEGHIEAPDLETDLTYLGEKVAAGVDFLITQL
FFDNRFFFDFVERARSRGIHVPIIPGIMPITNVAQIERFTRLCGASIPPALQARLDAVRH
NEDAVRSIGIEHAAAQCRDLLAHGVPGIHFYTLNQSPATRAIVEQLQRGPVACPAS
>A0A1A9JPP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas koreensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETADHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A7G8X7X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. resist|TrEMBL
MNLLDTMKERILIGDGAMGTLLYSHGVDLCFEELNLTHPDQVLRIHQAYIEAGADIIQTN
TYGANYIKLARHGLEDSVKKINKAAVQIAKNAAGKNTFVLGTIGGIHGSRTSIGTKDEIK
RSFREQLYCLLLEGVDGLLLETYYDFDELTTVLKIAREETDIPIITNVSMHEAGVLQNGI
ELIDALQQLEDLGADIVGINCRLGPHHMLKSLETVPLMKRALLSVYPNASYPGYKDGKLF
YENEPEYFEKFALSFRKAGVSLIGGCCGTTPEHIRALVKGLTIREPIQEKLVKKKEVKTE
VVESELKESQPPTLLETVRKRHSIIVELDAPKHLNTGKFFEGAQALKDAGVDAITLADNS
LATPRICNASMASLVKQKIGATPLVHITCRDRNLIGLQSHLMGLHTLGITELLAITGDPT
KIGDFPGATSVFDVTSFELIQLIKQFNEGISKSGKSLQQKTSFTVAAAFNPNVRHLDRAV
ERLEKKIEAGADYFITQPIYSTEKIIEVYEATKHIETPIYIGIMPLTSSQNAEFLHNEVP
GIKLTDQVRARMALSDGNREQSTKEGLEVSKELIDVALEHFHGIYLITPFMRYDMTVNLT
EYIHGKVDVIVAREVVQTESIVY
>A0A8H4B845|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor circinelloides f. lusitanicus|TrEMBL
MKVVDKITKAENEGRTYWSFEYFPPKTEMGVQNLYDRMERMQRFGPEFVDVTWGAGGTSA
DLTMDIVATSQSVYGLETMMHLTCTNMPVESIDTALKAAKACGCQNILALRGDPPKGQLN
WESCENGFNHAVDLVRYIRKNYGDYFCIAVAGHPEGHIDNEDKEDDLLRLKEKVDAGADL
IVTQLFFDVDVFVQFVKRCRDIGITCPILPGIFPIQSYAGLKRVISFNNNTVPQKIWDDL
ESIKDDDQAVKDYGIDLAVEYVHQIKQQTGINGFHIYTFNLERSSRLILEKLGLVPEQEH
VKPLPWNPSLGPNRTKETVRPIFWKNRAQSYIQRTESWDEFPNGRWGDARSPAFGEFDRW
GVSIKYPVEKRLAMWGEPQSPDDIALLFAKYCKGRLEGLPWSAQKLEPETDTIKQRLAAI
NLLGYLTINSQPAVNGAKSNHPVYGWGPKNGYVYQKAYIEFFIPPSKLDELVQKIGADPE
VTYFAVNKNGDLRTNTVDDEPNAVTWGVFPGKEIVQPTIVEPTAFMAWKDEAFGLWNEWA
HTYDRQSLAAEVILDIYENWYLVNIVHNDFQDENGIWRLFDLEIDGDLSKKLRRGSGSL
>A0A7C3XUT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKPKTPSKLEKILASGQMAVTSECGPPRGSDPEVIIRKAEKIRHHVDAINITDNQTAMTR
MCSLAACIRLKLMGLEPILQMVTRDRNRIALQSDILGAASFDIYNILCLSGDHQKFGDCA
LGQNVYDLDSLQLIQLVRHMRDEGKFLGGDPIERPPRMFVGAAENPFADPYEIRVPRLAK
KIAAGVEFIQTQCIYNLDKFEDWLNKARDRGLTEKVYILAGVTPLKSIGMARYMKNRVPG
MDVPDEVIKRLAGTPKEKQPEEGIKICVESIQRLKEAKGLAGFHIMAIEWEEMVPEIVER
AGLYPRPQVE
>A0A7V5U390|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfatator atlanticus|TrEMBL
MSNEKYRSHLERVLREGHFAVTCEIGPPKSADGDVVRQKARLIRGFVDAANITDCQTAIV
RMSSIASGVLVMQEGVEPVIQMTCRDRNRIAIQADLLGAAALGIKNLLCLTGDHQKFGNH
PEAKGVFDLDSIQLLDMVRRMRDEKKFQCGEEIKGKTVEFFLGAAANPFADPFEFRVHRL
AKKVAAGAQFIQTQIVYNLERFRKFMEMARDLGLTEKVYILAGITPPKSFGMARYMKYFV
PGLDVPDEILKRLKDAKDKREEGIQIAVEIIEQVREIPGIAGVHIMAIEWEEAVPEIVKR
AGLHPRPLAEEVKVEVPRPAPEIVPEKPEVEEEVPEAPPKVEVPAEALKEIFGSLRSSME
ALRDGINLLHEGLASLERALLGGPAERPAPPEIRPEERPEVKPEAPVVSKEEEERAQKVA
DLLSAAKAAREAGELAKAEALYRQVLELEAENEIAKSALAEIEKERLVEELLKEAEKKLK
EEDLDGAEAAYQKVLEIYPQKTEAVKGLEKVKELKAARVEKKPEEKPPVEERPAVEAKAP
EVADILVFAELSKEYRPVSERAAGIPEDVYKEPGTAYIREVTIGEGEKAITIGGTNVLPF
HLFEGEMKNPPHVAMEVLDVKPEDWPEALAKYFADVFDDPGAWAKKCVEVYGAEAINVYL
VGTDPNFLDLGPEHAAKVVEKVAQAVDVPLVIWGSGSAEKDVDVLREVANVLGAKNVMIG
PVVDTNHRALGATAMGYGYSLIASSPIDVNLAKQLNILLENVGVPLDKIAMDPSVGALGY
GLEYTYSVMERIRLAALYAQDEKLQVPFVINVGREVWKTKEAGLPSDDMLGDQEVRGIAL
EAITALALLLAGGDFLIMRHPKAIEVTKRVIDGLMAQ
>A0A8J2XUF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puia dinghuensis|TrEMBL
MKVIDHINSAKDTLVSFEILPPLKGKTISSIYEHLDPLMAFNPSFINVTYHRSETMFKKK
ADGTFEKVEVRKRPGTVGICAAIMNHYKVDAVPHLICGGFAKRETEDALIDLHFLGIDNV
LVLRGDAAKNESSFEPEPDGHRYAIDLLKQVVCLNQGVYLEEDIKNGGKTNFCIGIAGYP
EKHFEAPNLETDLMYLKAKVESGAEYITTQMFFDNQKYFDFVKICRDQGITVPIIPGLKP
ITTKKQMSMLPKVFHVDLPTDLSKAILQCKTDADVEQVGTEWLIQQSRELKKAGVPVLHY
YTLGKPKVIEATVKATF
>A0A7V4ZS13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKAGSNLEKILSKGLFAVTGELGPPKGNDVSVVKRKADLLRGYVDAVNITDNQTAIVRMS
SIATSTLLLQMGIEPVMQMTTRDRNRIAIQSDIFGATALGIKNILCLTGDHHTFGNQVDS
KNVHDIDSIQLIDCVKTMRDQGTLMGGEEKIEGKIELFIGAAENPFADPFEFRVIRLAKK
IKAGVDFIQTQCIYDMKRFKEWMKMVRDRGLHEKVHILAGVTPLKSGGMARYMAKNVSGI
IIPEEIIDRIVKAKKPAEEGIKLCVEQIQELKEIEGIHGVHIMAIEWEQMVSQITEMAGL
LPRPKIE
>A0A7V5U4Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
QDEGAEFAITQLFFINENFFRFRDMAVKSGVNIPIIAGIMPVIDLSQLERFRNMCGCIIP
DHLREQLTKNPDRVIEIGIEYSFSQCEELLRNGVAGIHFFTLNRSQSVVRIVNDLRESGY
F
>A0A7X8GGW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSQDNGMKSGSNLEKVFRAGHLAVTCECGPPKGADVEHLKKKIQMIKGYVDAANVTDNQT
AVVRMSSIGASAILAQNGVEPVMQMVTRDRNRIAAQSDLFGAYALGIRNMLCLTGDHQKF
GNHPFAKNVFDMDSIQLLNMVRTIRDEGKVNSGDPVEGGVSMFFGAAANPFADPFEFRVI
RMAKKIHAGADFIQTQCIYDMVRFKEFMKMARDMGLHEKAFIMAGLTPLKSVGMARYMNR
NVSGITIPEAIIKRLAGVPKERQAEEGIRICLEQIEELKEERGIRGFHIMAIEWEEKIPE
IVERAGLYPRPAVA
>A0A7V3RZ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNYRSGSRLEKVLAGGKFALTVEVGPPRSADPEVMRQKAGLLKGYADGYNVTDNQTAVVR
MSSLAGAKLLLEAGCEPVLQMTCRDRNRIALQSDLLGASALGIRNCLCLSGDHQKAGASG
KLKGHPGAKNVYDVDSIQLVSILKGLRDQGRQEGGDTVDGPVPFFIGAAWTPLAPPEEFR
VLRLAKKIAAGADFIQTQAVYDVRRFASQLKKAREMGLTERAAILAGVIVPRSAAMLKYM
NKNVPGVEVPEELVKRMEKAGEPQAEGVKITLELLDALRGLPGLAGVHLQAIEAEQLLPE
IIRAAGLYPRPEV
>A0A661NB37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRITDMFGKAEPVVSFEFFPPKTDAGMEALYRTIAALKPCGPSFVSITYGTGGGSRNLTI
DLVERVKAELGIETLAHLTCADATKGDIAIICRRL
>A0A496YNG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNSSHSLKQILGQGHFAVTAECGPPKGADPEIILKKAEYLKDKVDAINVTDNQTAIVRMS
SLAACALLKSAGLEPVLQMVVRDRNRIALQSDILGAAALGIQNVLCLSGDHQSFGNQPQA
VGVFDLDSIQFIQTVKAMRDEGVILGGESLSKAPDIFIGAAANPFADPLSFRVTRLAKKV
KAGADFIQTQCIYNLDRFRSWMKQVADRGLAEQTYILGGVTPLKSAGMAKYMKNRVAGMD
VPDEIIKRMEGVPKDKQREEGIRICVETIEQLKEIPGVKGVHIMAIEWEEAVGEIAERAG
LLPRPAVE
>A0A661ISY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
LAGIVLLASVGMARYMNANVPGIFVPEEMIQELASAPKGKAIEKGIEIAARLIRTIRDEG
ICDGVHIMAIGREERVLDILDAAGM
>A0A257KEW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. BFFFF2|TrEMBL
MKVTEHIHTAAGKTLFSFEILPPLKGHNINELFDEIHPLIDFNPSFINVTYHREEFTFKE
VGDGLLQKKVVRKRPGTVGICAAIQARYGVDAIPHVLCGSFSREDTENLLIDLDFLGIDN
VMALRGDALKSEVYFTPEKDGNVYASELVTQINNLNKGIYLDEEQQDSSPTSFCIGVSGY
PEKHLEAPSFESDLQYLKQKVDCGADFLVTQLFFDNQSYFDFVKRCREAGILIPIIPGLK
PLTHLNQLRMLPQRFNIDLPHELVKEAKKAPHAKAVKELGIEWCIAQSQELKDAGVPVLH
YYSMGKSASIEAVVRTVF
>A0A661IVK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKEGFKSNSRLERILKAGHFAVTGECGPPRGADPEAIRKKGELLKGCVDAVNVTDCQTAV
VRMSSLSSCLILKEMGFDPILQMVTRDRNRIAIQSDILGAAALGINNILCLTGDHQKAGD
HPQAKNVFDIDSIQMVAAVKAMRDEGKFMNGEELTVRPRLFIGAAENPFADPFEIRHLRL
AKKVKAGADFIQTQCIFNVKRFKEWMKRVVDMGLHEKVFILAGITPLKSVGMARYMKNMV
PGMDVPDEVIERLKGVPKEKQGEEGVRIAIETIQELKEVEGVHGVHIMAIEWEEKVREIV
EGAGLFPRPEI
>A0A495I0W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. 94|TrEMBL
MIAANAQGTGFPVSFEFFPPKTPEGADKLRAARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPEADLNAYIAKVQAGADSAITQYFYNSD
AYFRFVEDTQRLGANVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A2N2H6X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-21|TrEMBL
MKTQSVLERVLEAGLPAVTSECGPPRGAVPEKVKEKAEKLRGYVDAINVTDNQTAMVRMS
SFAACLIIKQMGLHPILQMVTRDRNRLAMQSDIIGAYSHGIDTMLCLSGDHPCFGDHPMA
ANVYDLDSIQFVQMVRKMRDEGKFQGGDDILNAPRMYIGAAANPFADPFELRVARLAKKA
RAGADFVQTQCIYNLERFGKWMEGIRERRLHEKIHILAGVTPMKSAGMAKYMKNKVPGMD
VPDGLIKRMSGIPKEKQAEEGIKICVETIQELKEMKGVAGFHIMAIEWEDRVPEIVERAG
LYPRPL
>A0A1C6C8M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Flavonifractor sp|TrEMBL
MKIIDILSQDKVTLSFEVFPPKTSDSYESVAKATQEIAALKPDFMSVTYGAGGGTSDYTV
GIAAGIRDKYGVEPLAHLTCASSTREHVHQVLGKLKESGISNVLALRGDIPEGGAPAHDY
HHAAELVREIKASGDFCVGGACYPEGHPESPTKASDIDYLKAKVEAGCEFLTTQMFFDNN
ILYNFLYRIREKGITVPVVAGIMPVTNGKQIARICKLSGTYLPEKFKAIVDKFGENPAAM
RQAGVAYAAGQIIDLIANGVNHIHIYSMNKPEIAAGIQASLSEVLK
>A0A5B0ENK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paeniglutamicibacter gangotriensis|TrEMBL
MSIGTTAAPPSLSYELYPPVNRDATEGVFTSIQALESTDPDYVSVTYSGSPARRNASLEL
IEHLIQNTRLRPLAHLTCVGESRETLQNLIRHFISLGVRGVLALRGDLPTDPEQWRGEYP
FARYLIELIRAVEADHSAALAGGRLGVGVAAYPIRHPESPSFEHDVEVLLAKERSGANYA
ITQVYFRADEYTNLVESARRAGVSIPIIPGVIPLNSVRRLNRLCAMAGIAPDPILAHALE
TASSDSERHRVGVDAAVNLARRAFDDGAPGVHLYTFNDHRGSLDVVEQLELPRTRARASN
AWATRAAV
>A0A2D5SG48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MHLIELYKKQNFVFSIEIFPPKTEKGMDKLKMTLEKFNGYTPDYFSVTYGAGGTSRANTH
EMAAHIRHDLGVPVMAHLTCVSHSAKEIDDVLTKLKNSNIENLMALRGDPTLGTEHFILP
EGGYHNAGELISAVRKHSDFGIGAAGYPEGHVDNPDKDDDRKHLHGKIAAGAEFIVTQFF
LDNTYFLRWRDKLREEGANVPLVAGILPPSNWKATKRMSEMCGVSIPQDLAEALLKHEND
PGASKEIGFVHVEKQIEGLLREGVEGVHLYALNNLDTVKRLGPKLREAAGTSPACSAD
>A0A357FA09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEILTTISDSFESDRFMEPADDLQENIEQNTTWSMEILPHNIAEVSLIPEFINEIYITMI
PGATCLETIEAAQKIQAVGKQAVPHIAARSFTGAEDLEECLSGLEAAGIERALLIGGGHS
ELAGKISCVMDMLKTGLFAKYGINAFDFAGHPEGNPDDPNSAVHMLEKLRWAEEQGASAR
IVTQWSLDTECTNAWISGLREKGVNNPIHLGIPGPSTLKTLMRFAKICGVKASTTVLRKQ
GLNLSKLMFVNKPDKIIEELRGYDQLHLFPFGGIERSSAWLTEWQTKSYI
>A0A286IRT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagales bacterium TFI 002|TrEMBL
MAKVTDHINNANGKPIFSIEIIPPAKGSKIEDLLSSIEPMMELNPPFIDVTYHREEYFMQ
KMPDGSMKEIRTRKRPGTVGICSAIMHKFDVDPVPHILCGGMTKSDTEDLLIDLNYLGVQ
NVMALRGDVAKPHNTFKAKKDGHCYASELVVQIADMNKGKYLHEEEPYFNNSDFCIGAAG
YPEKHFEAESLDADLKYVKEKVDNGAEYLVTQMFFDNQKYFDFVKKCRAIGINVPIIPGL
KVLATKRQLSILPDLFFLDMPAELRKEVEKAKDNEAAKQIGVDWCIQQCKELVDFGVPAL
HFYTMSKSSTTMAVAKAIF
>A0A318BJG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. 3335mG|TrEMBL
MTTTISDLEEARRALDAPLFADLAGDCAVSFEFFPPKTEKMEAALWETVRALEPLAPKFV
SVTYGAGGSTRERTHATVARIARETSMPAAAHLTCVEASKAEIDQVAEQYWRAGVRHIVA
LRGDPPTLGQKFVAHPDGYANAADLVAGLQKLHPFEISVAAYPECHPDSEHQAADLDNLK
RKIDAGATRAITQFFFTPEAFFRFRDAAAAAGITADIVPGILPVSNVGQVRKFAGLCGAS
IPPWMDRLFEGLDDHPGARQLVAATVAAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPKTTPVAAAA
>A0A3P4M1W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gulo gulo|TrEMBL
MDHPTPKVFPSRSHGPSLGLWALEAGRVRFSVPPSISRNLAMVNEPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQGQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYLS
GEPNQHGYKVTCLPWNDEPLAAETSLMKAELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAFLAGS
>V7DBF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas taiwanensis SJ9|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVAPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3R7LQC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylarcula marina|TrEMBL
MSRTTPSISFEFFPPKTLDASFRLWETARGLAPFAPDFVSVTYGAGGTTRKLTHEAVTTI
NRHYGLKVAAHLTCVEATRVETMKIVQDYADAGIREIVALRGDAPKGQDRFTPHEGGFAN
SIELIEAIAERGDMTIRVGAYPEPHPDSNGTDADVAWLKRKVEAGATSAMTQFFFDPETF
FRFRDKCEAAGIDAPVIPGILPIQSWGGTKRFAAACGTSVPQWAEDAFAETDGNPEAERE
LATRICIELCEKLIAGGVDRLHFYTLNRPELTRDVCLALGIKPTRKLEEVA
>A0A353QQK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEVNLRLRDELESGRFVITAEICPPRGTDVASFIEKARLLRGKVAAANVTDNQRAVMRLS
SLACSVLLLNEGIDPVFQVTCRDRNRLAIQSDILGAWVLGVKNVLALTGDHVAFGDHREA
KAVFDIDSVQLVGVINTLNQGRNMKETELRGKTGFYIGAVVAPEADPWEPEEIKFEKKLA
SGATFFQTQAIFDMDRFKRFFEKAEKTGAKVLGGILLLKSAKMAHYLNNNVPGVTVPQGL
IDEIEAAPDQLKKGIEIASRQVRELKGFSHGAHIMAIGQEESVVNIIEGA
>A0A661RC05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSELKSGSNLEKVLTAGYFAFTGECGPPKGANVAHLKEKFQYLKGNVDAVNVTDNQTAVV
RMSSLAASRLMVEEGLEPNFQMVCRDRNRLAMMSDILGAHALGIRNMLCLSGDHQTFGNH
PQAKNVHDIDSMQLIALVKKMRDQGKFMNDDDIDVAPKLFVGAACNPFADPYEFRVHRLA
NKIEAGADFIQTQCIFNMDRFKDFMKKVVDMGLDKRCHILAGVTPMKNAGMANFMKKFVP
GMDIPDALINRLKGVDKRDQPEEGICFALEQIEEFKQMQGVAGVHLMAIEWEHKVPEIAQ
RAKVLPRPAV
>A0A1E3QX95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Babjeviella inositovora NRRL Y-12698|TrEMBL
MSVLNPLFVTVTWGAGGSTSAKTLDLVAMCQRELGFTTCMHLTCTNTTRATIDDALARAK
AAGVRNILALRGDPPRGEELGWDNSLSDFQYAVDLVRYIKKQHGDFFCIGVAAYPEGHVE
GSDSSGQSPAKDMPFLVEKIKAGADFVITQMIYDVEKFLAFEHTIRENDDIKDVIVLPGL
MPINNFSVFHRASKLSHASIPTSILAQFPPEIQADDNLVKQVGVDVMCDVIQQMYTRTDK
RVRGFHFYTLNLEKSLAQIVEKSPLLQRIFDTASFNETLHVDGSSDLNKLVREKRSDSGS
FKNTVVFDDAPNARPGSHKPSSSYHQRVLTISSGQGTLGRDATWDDFPNGRFGDSRSPAY
GEIDGYGPSLKVSVEAAVALWGRPENPKDLAKIFVDFLTNKISNLPWAASADGGLNPETA
LIQEHLIELNERGWFSLASQPATDCTKSQDKIFGWGPRGGYVYQKSFVELFITKAEWECT
LKPKLEQDEMASYYVADNGSFFESNLPPKSVNAVTWGVFPDREIAQTTIVEEESFKAWKS
EAFSLWQEWARCYLPGSRSNTLLASVLEDYYLVSIVHHDYKNETALWDLLLL
>A0A644W971|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MFIRDILGRTRPAVSFEIFPPKPETPLETIFDTIAALRKLSPDFISVTYGAGGSSRERTG
EIASATRGYPEGDVRRFEELLKKFRTGEKGDGEGFSALFGKGPEDFRDRLRRRE
>A0A838P3S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MLTLRDLLSDSRVHVADGAMGTMLYGRGVFLNVCYDELNLKQPDLVRDIHREYVRAGAEL
LETNTFGANPVKLATHGLAGDTERVNSAAAGLAREAAGERAAVAGAIGPLGVRIEPYGEM
SVDEARHAFARQVRGLLAGGVDGFILETFSDIAELGAALQAVRGQCDLPVIAQMTVGTDG
RTHYGTDPEVFGPELEALGSDVIGVNCSVGPHGVLEAIEKLARVVSVPLSAQPNAGLPRE
VGDRKIYMASPEYMASYARRIVEAGARFVGGCCGTTPEHIRAIRGFVQSVSPRHVHVVAA
APQHSAGVEPVPLAARSRLGSKLAEGRFITTVEIVPPKGVDPAPMFTQVRQLKAAGVDAV
NVPDGPRAQSRMGALLSALMIEREVGLEAVVHYACRDRNLLGMLSDLLGASAAGIRNLLI
VTGDPPKMGPYPEATAVFDIDSIGLTNLVSRLNRGLD
>A0A838NF51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MATLRDLITDSRVHLLDGAMGTMLYNRGVFVNVCYDELTLKQPGLVQEVHEAYVRAGAGI
IETNTFGANPVKLSAFGLEEQTEEINRAAAGLAHRAARGRAQVVGAIGPLGIRIEPWGPT
AKSEALAHFTRQTRGLAEGGVDGFILETFSDLEEIHAALEAARAAAPELPVIAQMTVGED
GNTSYGTPVETIAARLVEWGADVVGLNCSVGPAPMLEAIERMAEVTATPLSAQPNAGLPR
AVGDRRIYLASPDYMAQYARRLIAGGTRFIGGCCGTTPEHIRRIRECIADARPRRVVVGT
PPIPPSQATGARPVSLAARSEWGRKLATGAFLRSVEIVPPRGWQPTTMLEQCRALRAAGV
DAVNLVDGPRAQSRMGVVPAALLVEREVGLETVFHYTCRDRNMLGMLSDLLGAAGGGLRN
VLIVTGDPPTAGPYPDSTAVFDIDSIGLTNVVCRLNQGLDPGGTSIGEPTRFVIGVAANH
GAVDRERELERFRWKVEAGAEFAVTQPVFDPDELAGFLERIAPWRIPVIAGIWPLTSLRN
AEFLANEVPGAQVPESVLERMRRAEAAGAGAAHAEGIRIAQEVLQAVRGMVQGVQVSAPG
GRPEVALEALGQPTA
>A0A8D6H9Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. TY59|TrEMBL
MPADSGCPKRMEFGPCGGVRPDGRCEMLPKPCAFDDVVLWSGHRPAPRRVPAPLVLTDFS
ATPFNPDDIAMTANILAPGCDAVLVGEHQNKPDFPPTLMASLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSIDVDTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGMTAAVP
ETPTAPPVQRRPARLVEKQHAGASLAVLNHVPSPDMVADFMTTARSVGLTIPVIAAVAVF
TDSISAAVLEGLPGLELDPVVMQQVLSAPDPVTAGIAAAVSEARALLAIEGVEGVNVSGL
ASASGPRIGAEIKAEVGRRVRAEAAP
>A0A7Z3BW38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSAPTSLRVQAFLDAFSLEVSARAMPALGAEATRIPRGTTISIPWLASDDDDARLAAARR
VRELGFEPMPHLSARRIGSRAVLERFLQHAANEAGVAQCLVIAGDLATPAGPFADSASII
ESGLLERAGIKVVAIGGHPDGHPVLGSDACWQVLEHKCQSIEARGMAPMIITQFAFDADI
VLAWLHALRARGVHVPVLVGVPGPASIARLVRYAAMCGVGASALMLSRYGISIGRLLGSA
GPEVFVDRLAGGLTDAHGLVSPHFFPFGGIAQSLDWIKQHRALPSVARR
>A0A4V3RJH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTASRLKAFAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYAAELISFI
RAEHGDAFRIEVGAYPETHPQANDALLDLKHFKAKIDAGADAAITQYFFNADAYFHFVDA
VRRLGVSVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAESVRAFGAEVV
ASLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLRG
>A0A2U8G2L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium fredii CCBAU 45436|TrEMBL
MSPDINPFDPSAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDTIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHEATPTETLVAERLGHLREGIEENQQQLAEAAAH
HPH
>A0A5C8QRA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. IB2014 016-6|TrEMBL
MALGTASTRTDHARTVRDLLATGKLSYSFEFWAPKTEKGERNLWNALRRVEAVAPNFVSV
TYGAGGSTRAGTVKATQQIASDTTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVKHPEGVTYAADLVRLIKESGDFCVGVAAFPEMHPRSPDWESDIRHFVA
KCRAGADYAITQMFFDPEDYLRLRDKVAAAGCDTPIIPEIMPVTNVRQIERFSQLSNASL
PPALKERILSAAEDPAAVRSIGIEYATEFCATLRAEGVPGLHFITLNNSTATLEIYENLG
LHEQS
>A0A256B8P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudanabaena sp. SR411|TrEMBL
MIEPPQSVFEQSESPFTKFRKAIASKEFLITAEVSPPKGSDPTHMLEQTRSLKGRVHAVN
ITDSSRAVMSMSPVAASVLIQQQIGIETVCQLACRDRNRIALQGDLFGAAALGITNILAL
TGDPVKAGDSPDARSVFDYESVRLLQLIQKLNQGLDANGKALPHQGTDFLAGAAVDPQSP
SWSGLQKRFERKVNAGAQFFQSQLITDFDRLDKFVNQIASQSDKPILAGIFLIKSAKNAL
FLNKFVPGVQIPEHIIDRLAKAKSPLQEGMAIAAEQIQTARQICQGVHIMAIKAEHLIPE
ILDRAGVAVL
>A0A644SIR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MKVTEHIQNANGKTLFSFEILPPLKGQNIQSIFDAIDPLMEFNPAFIDVTYHREEYEYVE
REDGLLEKRVVKKRPGTVGICAAIQNKYGVDAVPHILCGGFSKEDTENFLIDIDFLGIHN
VVALRGDAVKTETYFKPEKNGHTFAKDLVEQIVKMNHGTYLDESLENSACTDFNIGVAGY
PEKHMEAASLEQDIYHLKKKVEAGADYIVTQMFFDNQKYYDFVEKCRTSGINVPIIPGLK
PITTKSQLSMIPHRFKVDLPNELVIAIAKAKDNKEVKEIGINWCIQQSKDLMKNGAPVLH
YYSMGKSEVVKRIASEVFKD
>F8F2E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema caldarium (strain ATCC 51460 / DSM 7334 / H1)|TrEMBL
MNISLELVPRDTQAVTEGLAVVSRYPDISLINIPDLLRFPIRSWQACTLIPPQYHTIPHL
RAIDFNLEEPFPLTAYFKEHHIDTVLVVAGDPPQDMKHRVYPTHTTDFIKKLKLEMPQLT
IYAAFDPYRSNIRYELDYLNAKEDSGADGFMSQPFFDVRLLEIYAEYLEGRRVFWGVSPV
LSEKSRNYWEARNRAIFPRSFRPDLHWNISFGRQVLQFCKTHHFDLYLMPIKVDLDTYLQ
GLFS
>A0A366I9P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalibaculum bacchi|TrEMBL
MNVAQIMKERMSFSFEVFPPKQDKPVEPLLDTLDHLYKFKPDFVSCTYGAGGTNAGRNVE
ICKAIKDSGKTIPVTHFTCIGNSKEKIKRELQNYLDIGVDHILALRGDYPKGWEGTRGDF
NYANELVEFIKVHFPQFTIAIAGDPEKHVECHSFDEDISHLRVKQDCGGDYIMTQLCHDV
DQFQWWRDRLIESGITLPIDVGVMPVLAKDPTIRMAVSNGSGIPRDLAEVIGRYGENPED
FKKAGIEYTVKQIYKYMNAGIDGLHIYSLNKWEDVAKIVNKSGIRKMHN
>A0A4Q7HAB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas moorei|TrEMBL
MKAMYWESSMSAIRPELFQSYSLETTAKDAAGFVHTRALMPEGVPVNIAFIGSETFDDRL
TAIGTLRSCGASPRPIISARRLTSSDVLGSFLERAVAIGKVREIFLVGGDPSTPKGPFND
SMDIIRGGFLDPRIIETVGIAGYPEGHPRVDDDVLWGYLKLKVETLMRNGFNVEITTQLS
FDPDAVVSWVERVRREGIHVPIRIGIPGPSTVGGILHFARQCRVGTSIQLLRRFGWQITS
LLTEVGPDRFLASLIQETAQRDLGAMRLHIFPLGDLSRSINWFHEYEASHYS
>A0A4R1BD09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasulfuritortus cantonensis|TrEMBL
MSERIYSMEFFPPKTAEGAAKLRETRRQLAQLKPKFFSVTFGAGGSTRDRTLETVLEIQA
EGQAAAPHLSCIGSTRENIRDILETYKANGIRHIVALRGDQPSGVADPGEFRYANELVAF
IRAETGDWFDIEVAAYPEVHPQARNHDDDLRNFKRKVDAGANAAITQYFFNADAYLYFRD
ECEAAGIAIPIVPGIMPISNYGQLARFSAMCGAEIPRWLAKKLENYYDDNAAIKAFGLDF
VTGMCERLLAAGAPGLHFYTLNQAGLTSTLWQRLGL
>A0A286H2P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter rathayi NCPPB 2980 = VKM Ac-1601|TrEMBL
MSRARFEIIPAEDIGERAMRAFPDPSAVTLTVTSLPKHGTGRTADCAVELAGRGFRVVPH
LAARNVEGRGALERVLRRMDAAGIDEAFVISGDATSAAGSYSTSLELIRDAREIAPGLAL
DIAGYPEGHPRLSDESIERHLRERAPFIRSIVTQMCFDVDAVVRYADRLRAQGITADLWA
GVPGPVERSRLLTLGARIGVGSSLGFLRRSTSVAGGLLRGRRFDPSAFVARLESAAGERL
AGLHVYTFNELGSLAAFA
>A0A1I5GL52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerocolumna aminovalerica|TrEMBL
MKIKDYLLQHKLVMDGAMGTYYSRLVNNNNEISEYANLNAPDTIINIHKSYIEAGAKLIR
TNSFAANREALSITSGEQEKLIKASYDIAKKAVEESGKEVYIACDIGPISESSKTEEELL
EEYKFICDVFLKEKPEVILFETFSSFKYIRELVPYIKEKLPDTFIITNFCLDKNGYTAAG
ISITSLLEELAKTNEIDAGGFNCGIGSGHMYHILKKVPLPDNKYIVITPNAGYPEQFQNR
MVFMDNEGYFTENMKRIAGLGVDIMGGCCGTTPNYIKNINQHINMQDLNRGNRITYSQQV
TLSLKHENSSEENKENRSADGVIHKNNLYELFQPGKKVVAVELDPPFDAKDEKILECANK
LKNSTVDVITLADSPMGRSRVDSILMSVKIARETGMEVMPHLCCRDKNMIAMRSGILGAY
VNGIRNILVVTGDPIPSENRQSATGVFDYNSIQLMDFVKEMNREHFSEEPIYYGGALNYG
RGDINKIVERMQRKIDAGVKYFLTQPIFSKEDVDRIQSIKEKIDTKILCGIMPLVSYRNA
NFIKNEITGIHVPDEIVKRYHPDMSKEEAEWTGAEIANEIIEKLSPFADGYYFMLPFNRV
SLMDKIRII
>A0A5K7ZJK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina ovata subsp. sediminis|TrEMBL
MHVGNLYATQQKPAISFEFFPPRDEKAAEKFGAVVDTLAELSPDYMSITFGAGGSTRDGS
YQAVNQLLVEKKIPTVAYIAGFGLAPDEMTHELDRYRDLGVETIFVIRGDKPQDPDFKPH
PESFSYASEMIAFIKSRYDFCLGCAGYPEGHIQAQSLEADIGFLKQKQDNGAEYVVTQYC
YDNDTFFRYVEKCRSAGVSIPIIPGIMPVYTLKLTQMLSKICGTTITDEMQRGLDQLDAT
DKDAVLDFGVDFAVEQCRGLLKKGVTGLHFYTMDRSRSTRAILTRLREENLV
>A0A7G8PRL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Constantimarinum furrinae|TrEMBL
MTVLEHIENGNGKTQFSFEILPPLKGQNIQSIFDGIDPLMEFKPPFIDVTYHREEYVFAE
RENGLLEKKIVRKRPGTVGICAAIQNKYQVDAIPHILCGGFTREDTENFLIDLDFLGIDN
VMALRGDAVKTETYFRPEKGGNNYACDLVAQITQLNSGQYLDEDLANKTPTNFCIGVAGY
PEKHMEAPNMDSDIHFLKQKIKRGASYVVTQMFFDNRKFFNFVEKCRASGITVPIIPGLK
PLATKKQLNLIPHRFNAELPEELIKEVLKCKDNEAIKQLGIDWCTAQSKELMAHNIPFLH
YYSMGKSDNIKAIASNLF
>A0A1H8YS12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. TB|TrEMBL
MTFENYLNNKIMLADGAFGTYFASKYGTGALPECANITDPSKVIDIHSDYIKAGANLIRT
NTFACNTLNLGPDMKKLGDHISAGCRLAFMASSLYSDTSDIQDSNTGIPNTGISYTDKSG
SDENSDARINDTNAANQGKRQIFVAGDVGPIPFIPGQDDEKISEEYFFMVQTMYNSGIKI
FLFETFAGIDNILKSLNWLKEKKENEPDLFVWVQLCSNQHGYTNEGIHVRNIIKELSAKK
LVDAAGLNCGIGPASMRNILDEIDFTGIKYVSAFPNASFPQGMLSRPIFSGNEKYFASKM
EEILSLGADIVGGCCGTSPDYTSKIAELDLSTKKSHAFKGESDLSIKVREKDSSFWVGKT
SKKLIAVELAPPFGADDKKLMDSANALTKYNVDAITLPDSPSGRTRADSILAGLKVTTET
GIATIPHICCRDRNIISLRSGLLGAYMNGIRNVLAITGDPVPTLMRQEAKSVFNFDSVGL
MKVLAELNREEFYKDPITYGGALSYNRPNTHVELSRMIKKIEAGASFFLTQPVFSDEDIE
KLSFFKDKMKEVNSDVKLFCGLMPLVSYKNALFIQNEMSGINVPDEVIARYKPDMSREEG
EMVGVSVVRDVIAKTKDFSDGYYFSIPFNRVYLLDKILD
>A0A076MY08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis methanolica 239|TrEMBL
MRGRFAEQLSERVLVFDGAMGTVLHVAGNSLDRALPELTLSNPELVSTIHESYVAAGADV
LLTNTFGANRLRLAEHGCSVSARDINLAAVRLARQARRGVHRTIFVAGSVSPAVSSSARA
GVRADERAEVVREQVQALVDGGVDLLVLETFGHLDELVEAITVAAEVTDLPIVAQATFTS
DGLTPAGETPREVVKALTGLPVTAVGANCTVGPQRMLAILDGLRDAGDLPVGVHPNAGMP
RRTGRRFTYPAARAHFGRYARRFAEHGAAMIGGCCGTTPGHIREVVARLSDLRPRQANPV
TAVPKPRPAPPQSPLARRLARPGFVLATQVTPHGEPEDVERVRGAGLALVRGNFGEALRL
EREAGVDTITTVTAWDRSLAALQADLLGAHAFGLRTVVCETGTPVPLGDYPGADGIWEVD
SVGLIGLLAGLNSGRDHAGLTLATRTAFHIGARVNPGAEDPDAELSRTKAKIAAGAQFLI
TRPVYELEGLSRMVTELSGVDIPVLVAIAPLSGFAEAEYLAYEVPDVTIPPRALSELEAA
GKREAEVGLALAAELLDGARDLVRGAVVVADEHPGKIESLLRQEKSVLQL
>A0A850K0R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrionaceae bacterium|TrEMBL
MGYTHAGHIDALNQNIADFSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLIAAPHLTCIDANRDELIQIADDYWRNGIENIVALRGD
IPPGGGKPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVRVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRPTGA
>A0A8C5U071|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malurus cyaneus samueli|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDSDRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFEDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLESGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLERVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLRKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLNSPSQQ
>A5Z3D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium ventriosum ATCC 27560|TrEMBL
MNIADLFKKEHTVFSFEVFPPKKESGIETIYSTLNELKNLNPDFISVTYGAGGKGVANAT
TIDLCSYIKNELGTETIAHLSCLYNTKESIDRILDELDEKGVKNILALRGDVNPDFAIEK
DFKYASDLTEYIMSKNRGFNISGACYPEVHQEAANMIEDIQNLKKKVDSGADHLISQLFF
DDQVFFDFQEKARIAGINVPIEAGIMPVTNKKQIERMVSMCGASIPAKLSKVLQRFGDNH
EAMRDAGISYAIDQIIELAAHGVDGVHIYTMNDPYVARRISEGVKNILKSGK
>A0A2V3Y0U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella effluvii|TrEMBL
MKIKDILGQGKPTLSFEVFPPKTEDKYESVEKAAAEIAKLNPAFMSVTYGAGGGTSQYTV
DIASTLHHEYQVTALAHLTCVSSTREKVHEVLEELKAAGIENVLALRGDIPKEGPVASDY
RFASELIREIKACGDFCIGAACYPEGHVESVSKTIDMDYLKQKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVVAGIMPVTNVKQIIRSCQLSGTYLPSRFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANGVDAIHVYSMNKPDVAAKIKENLSEIL
>A0A419GDI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MSDKDLKSGSKLEKLLSKGNFAVTAEIGPPKHASSEGIRHHALMLRDHVDATNITDCQTA
IVRLSSIAAGVHIMDCGIEPIVQMTCRDRNRIAMQSDLLGAYSLGMRNVLCLSGDHQKFG
NHPTSKNVYDIDSMQLIYSLRQMRDEKKFFCGEEIKEHEPRFFIGAVANPFADPFEFRVA
RLEKKVNAGADFIQTQCIFDMERFERFMEMVRERGIHEKVHILAGLTPLKSWRAAKYMQT
SVSGMIVPDEIIERLKKAEDPKKEGVEICVEQIKHVRNIPGVHGVHIMAIAWEEIVPEIV
EKAGLYPRPEAEKDK
>A0A2N6MDT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fischerella thermalis CCMEE 5330|TrEMBL
MLIFMLDTQNPTSLTSFRTAAKAGQFLITAEVAPPKGGNPEHMLKMAATLKGRVHAVNIT
DGSRAVLRMSPVVASAILLQHGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALTGD
PVKAGDHADCKGVFDLESVRLLQVIQKLNHGVDYNDKPLNDGALDLFPGAAVDPQCPSWS
GLQKRFERKLEAGAQFFQSQLITDFEILEKFMDKIAADCGKPILAGIFLLKSAKNALFIN
RCVPGVNIPQHIIDRLAQAKDPLEEGMKIAAEQVQIAQQLCQGVHMMAVKREDLIPQILE
MAGVTPVNQMVSL
>A0A562V8U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter argillaceus|TrEMBL
MGNRFREKLTTGQLVVTTEVCPPKGCDCGQFLATARTLAPLVDAINVTDNQGANMRISPL
AAAALLVREGIEPIYQITCRDRNRLALQSDLLGAAALGITNILALTGDHISFGDHPEGKP
VFDLDSVQLLDTIARLNNGQDLSGRALDSTPAFFPGAAAAPEAEPFEPTRYKLAKKVASG
AAFLQTQAIFDLSKFARFRELVQPLGVKVIAGIIVLKSAGMARYINRNIPGLTVPDELVA
ELEGSADQLGTGVAIATRLARGLTPLCDGIHLMAMGREDVIPQIVNDLEIN
>A0A542SAL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. SLBN-35|TrEMBL
MDVATRIEEGRGGFVLFAITPPRQSTPAERLPEIARATVERLEHLDLDGLVLYDIDDESS
RNPAERPFPFSPTVDPAEYRSAYLSSWRTPVIVYRAVGKYQREDLRGWLAEQDHRRTLTV
MVGASSSGTTAPVTLTDAQALRAEANPRLLLGGVAIPERHSRREDEHLRLIAKQEAGCRF
FVTQVVYDLNATKNLVSDYRYACEERGLAPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLRHSTNPLTASFEQAAATATELADFCRRLDVPFGLNVESVSIRREEIEASVELAARL
SAQLRSC
>G2NDP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. (strain SirexAA-E / ActE)|TrEMBL
MRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTREGTVRA
TQQIAADSTLTPVAHLTAVDHSVAQLRNMVGQYADAGIRNILAVRGDPPGDPMAEWVEHP
EGVRYAADLVRLIKESGDFCVGVAAFPERHPRSADWDSDIRHFVDKCRAGADYAITQMFF
HPESYLRMRDRVVAAGCDTPVIPEVMPLTSVRQLERFPQLSNASLPSALKDRILAVKDDA
AAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A7V5SJU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobi bacterium|TrEMBL
MRLPIQERLQQGVLVTDGSVAAELWRRGLREYPPEVYNLKQPTVVEEIHRAFVHAGAELL
QTNTVRANRYALERYGLSDKVYELNRKGVWLARCAALRRAYVAGVVGPTGRFLAPVGSLE
PEEARNAFVEQIVALVDGGAELLILKGFLEVQELCLAIEAAQVVSPGIPIIALKAFAEDG
AVLAGTLPQRVVQELERYPILALGAAGTVGPQRMVSLSRALVAVARKPVCALPDVSVPKL
TEEGWQYEPDPEYLARAAVQMYAAGVRILGADGGATVECIRAIAEGLRNAPPPEPVVPPS
PRPLQLEESPPPEPTEFARKLGRKLCITVEIDLPRGDAVAEALAAAQRLRRYGVDAVNIA
DGARARLRISPIALAHLVQERTGMECIAHLSCRDRNMVALQAELLGAHALGVRNILAVTG
DPTHIGDYPYATSVFDVDSIGLVRILQQMNSGKDLMGNPLGVRTNFTIACACDPAAEQWE
RELERLQRKVAEGARVVFTQPLFDVELWERFRSAVAGLPVYVFVGVLPLRSLRHAEFLHY
EVPGIRIPAWVRQRMARAETPEAALNEGVALAVEFLQAILPSVDGIYLMPPFRRYDVVGR
ILHELGLLLEPVSPPADAP
>A0A496QPA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MDAEEYITISADGTQSISRAIESAGLIDAIGSRLKSKANLLKEAILDPEIFCVTWEQIPG
RGAFEIQQETVIENVNHAAKGGMVHAISVTDNPGGNPALSTEMLCAQIKKTNMEPLVHLA
SRDKNRNEIESMLYGLAAEGVRNILVLTGDYPSKDAFEGMPKPVFDIDPVNVLRLVKIMN
RGLEHQVMGKSITLAPTEFFAGVCVSPFKKLEAEVITQYAKLKKKIVAGADFIITQVGYD
IRKVHELLQWLKLKGFDVPVLANIYILPYGVAKAMNANRIPGCVVTDKLVQDIALEREEK
DKGKSARLLRAAKQYAMARGIGCSGAHIGGHGITYEMVEYIVKKGDELSRNWRDLIMEFQ
YPQENGFYFFEEDDVKGLNRETPSPRIEKMPVPISYRFSRLAHVIMFNEKIWYFKLVQRF
LNFIDRKPKLKKIFGYLEHLAKTALFGCMNCGDCALFDAAYLCPMTQCPKQQRNGPCGGS
YGGWCEVFPGERKCIWVRAYHRLKAFGEEGKIEEHIVPPCNWALFETPSWLNFYLGRDHT
AKRLGIKAP
>A0A847YAW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermogutta sp|TrEMBL
MSARPPFAEFLQKGVVVFDGPMGTEIYRHHVFTNRCFDELSLSEPKLIRQIHQDYCDAGA
EVLTTNTFGANRPRLEKYGLGERLEAIIRAGVRLAREAADQADRPVYVAGSIGPLGAAAR
DEDAQQRLILEQVDVMAEAGVDFILFETQPNREALELCARAMQERPSVPYVLSAAVYEDG
ESASGETVERLLAPLAEELPQPVAWGLNCGSGPHGMLGAVDQALKFVRRPLIVQPNAGTP
KEVENRRIYYCSPEYFAEYGKRYVQLGAAAVGGCCGTTPEHIRALCETIKPLTRARTKPI
LVSPAGQAELKTPVPVADRSRFASRLARGRWVASVELVPPRGYNLEDIVTKSRLLHRHGV
DAVNIPDGPRASSRISPLITADRIQREAMIEVILHFCCRDRNLIGMQADLLACAACGVHN
ILFVTGDPPKLGNYPHATGVFDTDSIGMVQVQKRLNQGVDLGGQSIDPPTAAFIGVGLDP
TALDQERELDRFRQKVEAGAEFAITQPVFDPDALLRFLDRVQQYNIPIIAGIWPLASLRN
ATFMKNEVPGVIIPDWVMDKMASVSSRDDQWKMGVEIARQAVERVRDRVAGIQVSAPFGK
SEIALAVIEGSSP
>A0A7Y0HPC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium muellerianum|TrEMBL
MFIKDAFLKKETTLSFEIFPPKNLDNIFNTIQELKKFNPDFISITYGAGGSSKDRTVEIA
STIKNNYGIEALAHLTCAASTKEEIEEIINKLKQSKIENILALRGDIPEGFIQGKEYPYR
YAKDLIWKLKEDANLCIAAAAYPEGHNECKNLDNGVRYLKEKVDEGADLLITQLFFDNNN
FFEFKEKLYQYNIKVPVVTGIMPAVNKALIEKIQKLSGFVLPDKVKSFMSKYEYNEDDLK
KAGIEYASYQMEELLKNKVEGIHLYTMNKHDIVKNILDNVSFK
>A0A0W1S930|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloferax profundi|TrEMBL
MSPKFRSSTTSDGVQQLLTTPRYELMPFSSLGEQLEHLPDGAQIAITTSPQLGLDATVEW
TEKASARGYEIIPHIAARYVEDKQQLESVVHRLEEAGVTDIFVPGGDREEPEGSFESAYE
LLVALDELDHSFNDIGITGYPEGHDFIDDGTLADAMAKKEPYATYIVTQLCYDSDAVLEW
IDEVRSRGVDLPVEVGIPGVMKYNRLLSISQKVGVGDSVRFLRKTTGVVGFVRQLVGSRG
KYTPDDLVSGLAPYTDDEEYKLRGVHLYTFNQVPDLESWRKEKIEV
>A0A1M6WP41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium contaminans|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A1F2M053|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella sp. HMSC16C06|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A660STK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MLIKEILSEGKTAVSYEFFPPKNPPGWERLYQTITDLNHLNPAYISVTYGAGGATREHTH
ELVTQLVRETDAEIVAHLTCVGHSRDEMKSILDRYAESGVHNILALKGDTPSDRIVGRSK
PPGAFPHASDLVFFIKDNYPGMGIGVSGFPEGHPSSVNRLEELVFLKEKVDAGADYIVTQ
LFFDNRDYYDFVDRCIIAGITVPVIAGIMPVTGLSNMNHMAKLAPRTRFPSGLIRAVNRA
ETDEGVEMAGTHWATEQMRDLLDRGAPGIHLYTLNNSASTIRMGESLGLVGFHNLR
>A0A660UEK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MKSESKLERILEKGIFAVTSECGPPKGANYEVIHKKGEFLKGYVDAVNVTDCQTSIVRMS
SIASCAILVQMGIEAIMQMVTRDRKRIAIQSDIFGAYALGIKNILCLTGDHQKFGNHPTS
KGVFDLDSIQLIQTVKLLRDEGRVLGGDKIDGIPKMFIGAAENPFADPFEFRAIRLAKKV
AAGANFIQTQCIYDLTKFERWMEMVRQMGLHEKVFILAGVTPLKSFGMAKYMKNQVSGID
IPDDVMKRMKDAPKDKKAEEGINICVESIQRIRDIEGVHGIHLMAIEWEETVPTIIERAG
LLPRPEI
>A0A550HYL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. IB201691-2A2|TrEMBL
MALGSASTRTDRARTVRDMLATGKATYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSIAELRNIIGQFADAGIRNMLAVR
GDPPGDPMADWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDRDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDSAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A3D1FYN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
PLMEFKPPFIDVTYHREETIYKRLDNGLLQEKVVRKRPGTVGICAAIMHRYDTETVPHVL
CGGFSREETENLLIDLNFLGIENVVALRGDQAKHESYFTPHKEGNSFALDLVRQIKDLNQ
GRYLDEELQNTTATNFCIGVAGYPEKHFEAPSLNTDIEHLKAKVEAGADYIVTQLFFDNS
KYFAFVDKCRAAGITVPIIPGLKPLSTKRQLSILPQIFHVDIPDELVIQAIKCKDNAQVK
QLGIEWCIQQSKELRDAGVPVLHYYSMG
>A0A368E313|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|PS1 clade bacterium|TrEMBL
MTSISFEFFPPKSAEAEVKLWDVINELAAIKPDFVSITYGAGGSTRDRTHQCVKHLVTKT
DLKPAAHLTCVAASKSEVDEVIEDYASAGVKHIVALRGDMPDMEAFSPHPDGYNGSVELV
DALAQRGGFDITVSAYPEKHPESGDMQTDIDLLKAKIDAGATRAITQFVFDTEQHYRFRD
VLADNQINIPVIPGIMPTTNFKGVLRMSEACGASVPIWMKSKFDGLDDDLESRRALAIKL
ATNQCRDLINSGFENLHFYTLNQVTVTKAVCKTLSLEKVGV
>A0A651H1X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
MKITQHLQEAKGTLFSFEILPPLKGRGIESLYEGIDPLMEFEPKFINVTYHREEHMYKKM
PNGLLKRVSLRRRPGTVGICAALMNKYKIDTVPHLICGGFSREETESALIDLSFLGIDNV
LALRGDPIKSESSFVPEPEGNAYAIDLICQISELNEGKYLHQESAANGTAFCIGTAGYPE
KHFEALNMKTDLGHLKAKIDGGAEYIVTQMFFDNDKFFAFVDKCRAAGITVPIIPGIKPI
TTLKHIQFLPKTFHIDFPDELADELVRCKSDEEVKEAGISWAIRQSKELMERKAPVIHYY
TMGKSDTVQRIAREVF
>A0A6I7WF81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium HT1|TrEMBL
MTIKNKADLFSFEFYPPKTEQGDLNLEQVHRDLAKLNPDFFSVTFGAGGSTRDKTYDTVV
KIQKNGVSAAPHLSCVASTKENIREILANYREHGVSKIVALRGDLPSGMMSAGEFRFANE
LVDFIRVETGDHFQIHVAGYPEVHPQAGNATEDFNNFKRKVDAGADAVITQYFYNAEAYF
YFLDKCEKSGINIPIVPGIMPITNYAQLFRFSDMCGADIPRWMRKTLECFGDDKASIMAF
GEDVVSKLCQELLDNGAPGLHFYTMNQSKPTLAVWDNLSFA
>A0A498CXL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerotruncus sp. 22A2-44|TrEMBL
MSTRYWKFPAGYATIYWNHILIRKVGTSMPLDPSRPLLFDGAFGTYYYSLTGDEAPCELA
NLTSPDTVLRIHREYLAAGARAVKTNTFAANPVSLPDPEQLSRVIEAGWSLAERAAKETG
ARVFADIGGNNAETAPGDYLAVAERFLELGAREFLFETLASFDEVLPALGLIRERVPGAT
VFVSFAVSQDGYSRRGHYCRVLLEAAENCPLVDAAGFNCACGPSHMANLLRNLGPCRKPL
IAMPNSGYPSSINGRVLFEDNAGYFAQKLAALYEAGAEILGGCCGTTPRHITLAAEALAA
AARPAGTGLPGPSVPGPGAAAPGGGRPGARRKTIAVELDPPFDYDCSFILSASAELRRGG
VDFITVTDSPLSRTRADSLMTAAKIRREAGIEVLPHISCRDKNHIALRAGLLGAAFEGIS
HVLVVTGDPPTQTESRGRDGVFHLSSFDLISYIHSMNTEVFAKNPFVVGGALNVNAVNFP
RELERAKKKLSLGASALFTQPIFSDAAVENFLTARRELDCRLFAGILPVAGYKNALFLIN
EVSGIEIPPQVVEALRDKTLEEAAKISIAYSAGIARRVYDAADGFYIMTPLRKIAIVHGL
IEEIRREET
>A0A6N3A9Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLTKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKIDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQPNFEVN
>A0A259N6Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrovum sp. 34-44-207|TrEMBL
MESQKGFAKLFSFEFFPPKTAEGVEKLRHTQRQLSQLHPAFFSVTFGAGGSTREGTLGAV
LDILKAGDSAAPHISCIGSTKAMLKDTLDQYLEHGIRHVVALRGDLPSGTYGGGDFRYAS
ELVRFIREEVSQELIIEVAAYPETHPQARSAQEDLIHFKEKVVAGANAAITQYFYNPDAY
FDFIERCEQQHITIPIVPGIMPIGNFSQLSRFSEACGAEIPRWIRQKMLGYGDDSASIRA
FGLDVVTHLCDTLLSAGAPGLHFYTMNSAGLTSVIWDRLHLSSYR
>A0A5C6U2J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piscinibacter aquaticus|TrEMBL
MDEIRTPIPVSFEFFPPNTPVGSEKLRGVVAELGATNPEFFSVTYGAGGSTREKTLATVS
EIAAMGHEAAAHLSCIGATRESIREILATYRERGIRRLVALRGDLPSGTATAGEFRYAAD
LVRFIRDTEANHWHIEVAAYPEVHPQQRYAKRDLQHFAEKMGAGANAAITQFFFNADAYF
HFVSEARALGVSAPIVPGIMPFHNYARIAQFAQRDGIEIPRWVAMKMEGFMDDAASIRAF
GLDVVTQLCERLIAGGAPSIHFYTLNQSALALEICRRLARLV
>A0A433WCQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga solisilvae|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMAFNPAFINVTYHRSEHMFKKK
ADGAFEKVEIRKRPGTVGICAAIMNHYNVDAVPHLICGGFSREETENALIDLNFLGIDNV
LVLRGDAPKNETFFEPDPHGHSYASELLDQVVSMNNGVYLEDDLQSGVKTNFCIGVAGYP
EKHFEAPNMQTDMSHLKRKVENGADYIVTQMFFDNQKFFDFVNKCREMGITVPIIPGLKP
LTSKKQMTILPRIFHVDLPTDLSNEIMKCKTDKDVELVGTEWLINQSKELKAFGVPVLHY
YTLGKPQVIRKAVEAIV
>A0A512CDP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclobacterium qasimii|TrEMBL
MKVTEYLKNTDKTHFSFEILPPLKGQSLTNLLEGITPLMEFNPPFIDVTYHREEYMYKKH
ANGLLEKISTRKRPGTVGICAAIMNKFKVDAVPHLLCGGFSKEETENALIDLYFIGVENV
LALRGDAPKLEPNFVANKDGHQFASELVAQITGMNQGKYLHDETEIGFQTDFCIGVAGYP
EKHFEAPSLNFDLKKLKAKIDAGATYIVTQMFFDNQKYFDFVEKVRAAGINVPIIPGLKP
ITTLSQMVNLPKMFFLDLPDDLMVELEKCKNNADVKEVGIEWAIQQSKELVKYGVPTLHY
YTMSKADTTYKVAKEVF
>A0A1S7NK17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium tumefaciens str. Kerr 14|TrEMBL
MHKLPDISAASIIPASIEASPAQVLGASDLAGLFPQGVRVYLTDTGAASQERLVDAAGHL
RDLGYEPVPHLAARRIASRTGFEEQVRRLAGEAGVTDVLVVGGGVDRPAGPFASSMDMLS
SGIFDRCGIRQIAIAGHPEGSPDFNDDTAMAALRLKRDFAERSDAAMRIVTQFGFDPARF
IAWAEGLKASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTTLAKGHS
PESIVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGGADRSASQDSIAG
>R6NP89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:45|TrEMBL
MRGKTIYSNNASYYAEKMKDIAALGTDILGGCCGTTPEYIALLSGELQDVPKAAKKIENV
VTQEVTRTPSIFEEKLSRGEKAYIVELDPPFSGDASKVMKGAEDLRKCNVDLITLSDSPM
ARARMDAGQLAVKIQQKTGVAVMPHISCRDRNVIALRAGLLGMHMNDVRHFLIVTGDPVS
RADRERVTSVFDFNSIKLMQYVKEMNLEVFAQEPVYYGGALNYHGANPDAIIERMKRKAE
AGCGYFLTQPVYTEEDVERLTYIKEHIDTKIMCGIMPLVSYKNATFVKNEMPGIHVSDEI
VNRYREDMTREEAEEVAIELSVEIAAKLYDIADGFYFMTPFNRTGLIARIIEAIRQEEER
R
>A0A1F3NET4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium RBG_13_43_22|TrEMBL
MSVIDKIRNAKGPLFTFELLPPLKGHSIEKVYTAIDRLIEFQPAYINFTTHRNEITYKER
SDGLLEKRVTRLRPGTIALAAAVKYKYNITVVPHILCGGFTREETENVLIEMNFLGIDDV
LALRGDPQRGSRTFIPEKDGHTHTFELVRQIINMNSGKYLEESLEDTIATNFCVGVAGYP
EKHVEAPNSETDMENLKYKVESGASYIVTQMFFDNSRFFRFRDECKRIGINVPVIAGLKP
VSALNDIKLLPQTFHIDVPPDLVSAIKKCTTDREAREVGIEWATMQSRELIKEGAPGIHY
YTLGRSDNVARIVKASF
>G8PAR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pediococcus claussenii (strain ATCC BAA-344 / DSM 14800 / JCM 18046 / KCTC 3811 / P06)|TrEMBL
MKLVEVFKHKTVFSIEVFPPKTEKGSLKLHQALSELKGIEPDFISVTLGAGGSTNRGGTV
GVASEIQNHFDVPAVAHVPGLYRTKADVDELLDELEGQGITNILALRGDQIEGLKPVGDF
KYASDLVAYINQRGGFEIAGACYPETHQEAANSVNDIRNLKVKVDAGVDHLITQAFFDNQ
CFYEFREKTDLAGINVPIEAGIMPCLNKKQVLNMAKMAGIPVSQKHLAMMEHYDGNVEAT
RDAGIAYAIDQIVDLVAQGVDGIHLYTMNNGDTAQRIWKATRSLFAASVR
>A0A7J9RA39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilaceae archaeon|TrEMBL
MTIRYEANPPKILPGVDIDESISKFIDKIKLISTKCDAIHLTENVLGFKRVSPITVGKII
RKEIPDLPVTVSLRVRDKTKEEIESFVAEVIQAGFSGILILMGDPPQDGQKDSGLFPSQV
VNSLKEKQIDSKIDLYLSISNKANFSKIEKKLNAKPKGFMTQVIQNIDQVKNLAENLKGY
SVIPIVLFPSDKNEKSAKFLNLNLEQFRENFPEFLSQVHQITGDVLITSPSDFSGLNEFL
EKNQV
>A0A5E7RYG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A328KN20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dolosigranulum pigrum|TrEMBL
MTIIDKYQQKQVFSFEMFPPKGKHNMEKLHETIDLFSTLKPDFISVTMGAGGVGNSKGTV
DITDDIQQRYQIDSVVHLPSIHLSKPEVSDILADLKRRNISNILALRGDEHPGTSRSQDF
NYASDLIEFIKESGDFNILAACYPEGHTQSASIVEDVKHLKRKADAGVDAFVTQLFLDNE
YFYRFRERADIVGIDQPISAGIMPVTSKKQIERMIQLTGANLPKKFVSIIDRFGDNPKAL
LDAGIAYAVDQIIDLLAQDVNGIHLYTMNNSYIAKNIYRAIKNIV
>A0A0A8TIS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bereziniae|TrEMBL
MSKRIPISFEFFPTKTDAGAEKLKIVHQELQQFNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGDHFKIEVAAYPEMHPQAESYDADIQHFIEKVNAGANAAITQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVIKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A0C4UTR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria scopulorum|TrEMBL
AYGIHLGTEMCKKILAHGIKTLHLYTLNLEKSALAILANLGLIDMTKIKRPLPWRPPANV
>A0A4Y8KTB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium psychrophilum|TrEMBL
MTETTTSTPRTTHVPFSFELYPPKTDAAVSALHTTIDHLAAAGPEFLSVTYGANGSSRSS
SLEVLRYILEHTTVDPMAHLTCVGSSNVEASVLIREFLDAGVRSFLALRGDPPQGVAEGE
TFLGDLHSAAELVQLIHRVQAERVPYRETVIPGLPGARGVKTERDKVRIAVAGFPNGHPR
SRATSQDIDTLLAKQAAGANLGITQLFFHADDYLTFIERARRAGVEFPILPGIMPVTSPG
RLRRILELSGEELPSDLAIQLEVEPTPEGQREIGIAHATQLAQQVLDGGAPGLHLYAFNQ
HPTVLEVLHRCGALDTRKLHPASTRSASSYPAFSVAYPVRKSA
>A0A3B8T4B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciecola sp|TrEMBL
MVSYAQGVDSLNQTLSELRDINVSFEFFPPSNDKMENMLWKSVERLAPLKPAYMSVTYGA
NSGERDKTHNVVKRIQHDLGVPAVPHLTCVDASREELIDIAKEYWANGIRRIVALRGDLP
PGMEKPDMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGANEAIT
QFFFDTSHYLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTDVHVPNWLHKMYDGL
DDGDQTTRNLLAANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGLRA
>A0A3D5KXU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MSSPNKTTFSFEIFPPKPTSEPSVIYGTLDALQDLKPDFISVTYGAGGGANCKNTVGIAS
YIQNTCQTESVAHLPCLYLSESDLNGILEQLQENGIHNILALRGDRSETATPNGRFSHAN
ELISYIHDYDPSFHIMAACYPEGHPEQHSPAEELETLKRKVDAGASQFITQLFLDNDAFD
TYRNKVAQAGVSVPIEAGIMPVTNKKQIERMVKLCGATLPKKFLHILNKYEDNPEALRDA
GVAYAIEQIVDLIAQDVDGIHLYTMNRADVARDIDHAVHRLLQ
>A0A5N9H6X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MLIKDILKTSRTISCEFFPPKDSEGINNVLEVAGRLKPYNPSFVSVTYGAGGSTQAFSEE
ITLRLKRELNFEVMAHLTCVSQTQSEIDEVLERLVSAGIENIIALRGDPPAGDSNFVPVE
GGFAHASDLIKHIDHKFSFGIAAACYPEGHTESIDLYSDIQYAKLKVDNGADFLVTQLFY
NNQDFYDFVERAQKSGITVPIIPGILPILSAPQIRRFTSMCGASIPVQLDTQLDKHHDDD
KTVRQIGIDHAINQVQDLWANGVQGIHFYVLNRSYSVSKILDSLQIPDHTGLSKTTT
>A0A2W6ZL54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp|TrEMBL
MLLQQALKRGQFALTAEVMPPRGGDPGRTLAVAATLKGLVHAVNVTDGSRAVMRMSSLAL
CRLLLDIGLEPVLQLSCRDRNRIALQAELLGAHALGIPNLLCLTGDPVRAGDQPSARPVN
ELEAVRLLQMVSRFNAGEDPVQGALPDGPTSLFVGAAADPQSASWSGLQSRVRRKHAAGA
RFIQTQMVMNTDALKRFCGEVAAPLDLPVLAGVFLLKSARNAAFVNRVVPGAMIPQSLID
RLAAAADPAAEGIRIAAEQVQAYAGIAQGVHLMAVKAEERIPMILEQAGFGQLQPCCD
>A0A5T0IX12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHT
>A0A7C4RY15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium pennivorans|TrEMBL
MKVTEMVKERRIISIEIIPPKRGEDVENIYRTLDKLMNYDISFISITRHPVEVDYIEYED
KIVKVHKAKRPGTLGLTAALMNRYRIDVVPHLICVGMSKFEMEDMLIDLDIMGVDNVFVI
RGETDSSVENYNKGDYKYAVELVRQIKDLNMGKYLYTSAKPTNFCVGVAGYPEKHYESPN
LETDLKFLKQKVDAGAGYIITQMVFDAQVYKDFVERCRSIGINVPIIPGVKPVVSKSSVF
NIPKKFFVTIPQRFVEAIDNAKTKEEEFKVGIRFTVELVEKLIEYGAPGIHIFTMGRGEE
SCEVIKHTQSILK
>A0A1C6J7Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Blautia sp|TrEMBL
MKMKELFDRGEFAVSAEVGPPKGIHVDELVEEAKTYLTGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMFGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A6B5HCM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAATKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A2V4AJ40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella muralis|TrEMBL
MTSVLERLRGERPVFSVEFFPPRDAADEAALWHAIRELEQLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPLGDPYGEWV
PHPDGLSYAEELVTLVRSLGDFCVGVSAFPYGHPRSPDLATDTAHLVRKFDAGADFGIAQ
LFFEAEDFLRLRDRVAAAGCAAPLIPGIMPLTTPRTLAKTIELSGVHAPRRLLDRLEPLA
GDAKAFRAEGLDAVTELCERLLAEGVPALHFYTFNRSKATRELVGRLGLVPARA
>A0A243G601|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>L7P8G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Homo sapiens|TrEMBL
MGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSL
CQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPI
FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEEL
TSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQ
PNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKG
ENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPS
RTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNARETEAP
>A0A482KE01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Homo sapiens|TrEMBL
YPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEVDTFFRFVKACTDMGITCPIVPGI
FPIQ
>A0A3E4Z5F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola plebeius|TrEMBL
MKVIDLIKNSKEPVFSFEILPPLKGNSIQKVYHIIDKLREFDPKYINITSHHSEIVYLPQ
PDGNLKKTTVRKRPGTVAIAAAIQNKYGIQAVPHIICKGFTKEETEYALLDLNFLGINNL
LLLRGDSKPLDIAEKDLCLYHEHATDLQEQVNRFNQGIGLDGSKIEGIETPFSYGMACYP
EKHEEAPNMESDLFYLKEKVRNGADYVVTQMFFDNEKYYAFVERCRQEGIDVPIIPGIKP
VVFKNQLNVLPKVFRTDIPEAFASELRKCTTDEEVKAVGVEWCKAQCKDLLAHGVPGLHF
YTFMASDSVYKVAKEVY
>A0A0Q0R4J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A641A9G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIHEGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDNAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A2C9P8R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio mediterranei|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSTPTMEETLWKSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSETGLVAAPHLTCIDASRDELIDIAEDYWSNGIKNIVALRGD
IPAGGGQPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAGMNKVKVPGWMQKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQV
>A0A357WTT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MSIAELFKKKQTVYSFEIFPPKKTGSIETIYSTLDQLGGLSPDFISVTYGAGGNPADRST
CEIASIVKNKYHIEPMAHLTCVNDSREDIVEILRQLKENGIKNILALRGDKRPDIPPKSD
FHYASELVEFIRSQGEFHISGACYPHGHPESDNMIDDILNLRKKVDAGADHLISQLFFDN
SVFYSFLERARIAGINVPIEAGIMPVLNKNQIERMISLSAASLPAKFTKMISKYEHNPVA
LRDAGIAYAVDQIVDLISNGVQGIHLYTMNNPLVARKISQSISSLIS
>A0A084EUI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium yanoikuyae|TrEMBL
MTQTDRARHDAEGPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFVSVTY
GAGGSTRERTHNTVARIAKETPLAAAAHLTCVAASKAEIDEVADAYWEAGVRHIVALRGD
PPEAGTAFQPHPDGYKGAAELVEGLRKRHDFEISVAAYPETHPDALSAQSDIDNLKRKID
AGATRAITQFFFEADTFFRFRDTVAAAGIDADVIPGIMPVSNFAAVQRMSAMCNTDVPAW
MGRLFDGLDQHPAARQLVSATLAAELCRNLYMGGVRDFHFYTLNRAELSYAICHLLGLRP
QVTVDA
>A0A4S8ZWY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDGALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSIANS
APQNRVVIDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVE
FFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLL
EA
>A0A6B1CWV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MSLTALHPPARYSGAWQKKPLRHLLETTDTFVHIVELVTSRGLITERDGRKVLALARRLA
EHPQFHALSITDNPGGNAMINPDTLGTDLISRGQDVIIHLSCKDWNRNALQGRAWQLASE
GFNNILALSGDYPISGYQGTAGGVFDLDSVGLLEMFAAMNAGLKIKKGKRTQRMEATDFY
LGAVVNNHKRYEREVMPQYFKLAKKIHVGAAFVISQIGYDARKQDELLKYMALCGLDVPV
IANVYVLSRPAARFFHKGHIPGVEVTDELMAVVEKQAQANDKGRAFFLELAAKQCAIAKG
LGYRGAYLGGHLQYGDYEKILALAATYSEDDWRDFAVELCFSFADEFYFFEPQGDTGLSS
TTINRAYLASKEQAALRQARGHLPLSYKLNRRIHDQVFAPESAGFRTGAHLARALTEHPK
AAKLFHAAEHALKIAAFDCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTRQGKCEVGD
KDCIWARAYDRLKAYGEEEQMLGDAAVIKDAALQGTSAWTNAFLQKDHRSKKKDSQ
>A0A364USI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus warneri|TrEMBL
MSQFLNKLQNNVLVADGAIGTIFYSEGLDTCPEAYNLTHPEKVEHIHRSYIEAGADVIQT
NTYGANFEKLKAFGLEHKVKEIHKAAVQIAKKAANEDTFILGTVGGFRGVKQDDLSLSSI
QYHTEHQIDTLVDEGVDALLFETYYDLEELKGIVISTKRKHHIPIIAQLTASNTNYLVDG
TPINDALKQLVECGADIVGLNCHHGPHHMQRSFSHIELPDKAFLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIRYIKTSVKNLRPVTHKNVIPINKKV
NRKKDLNFKQSLTSKVKQGPTVIVELDTPKHLDTDQFFNNIGKLDDADIDAVTLADNSLA
TVRVSNIAAASIIKQRFNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEATKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITTHKEAIL
>A0A3B9MK16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MEPFRNILESDSIHVFDGAMGTMLYAKGIYINRCYDELNLTNPDLVQEIHAEYVSAGADI
IETNTFGATAHNLHQYGLEGSLRDINIAAARIAREAAGDRAYVAGAIGPLSLRIEPYGPT
SFDEAKEMFKDQAAALLEGGVDLFVLETFSDISAIRQALSAVRELCDLPVIAQMTILTDG
NTSYGTTPELFTARLDEWGADVIGLNCGVGPAIILSALEKMRGVTKKKLSAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRFIQSGAKFIGGCCGTTPAHIKLISDAVRAASPRAQRVVLS
SGPLGVVTEVPPADLKIVPPEERSNWSRKIVNGEFVTSVEVLPPKGVDAQKTLDSIRLLK
EAGVDGVNIPDGARAQSRMSAMATAVLVEQQIGIESVLHYCCRDRNLLGMMSDLLGASAL
GLRNLLLITGDPPKMGPYPDATAVFDIDAIGLTNMVNKLNHGLDIGNNPIGQPTAFCIGV
GVNPGAINLDEEIRRFEYKVEAGAQYAITQPVFDTEQLRDFIKRIEHVKIPIVAGIWPLV
SYRNAEFLHNEVPGVRVTPSIMERMRAASAISKEAGRDEGLKIARESLLEVRDVIHGVQV
SAPFGNVKYALEVFEALDGFASRQATQK
>A0A380G4E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus petrasii|TrEMBL
MSRLLNQLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADIIQT
NTYGANFEKLKTFGLEHKVKDIHKAAVQIAKRAANPTTFILGTVGGFRGLKQEELPLSTI
QYHAENQIDTLVEEGVDGLLFETYYDLEELTNIVTSTRRKYDIPIIAQLTASNTNYLVDG
TEINEALKQLVECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRIIGGCCGTTPKHIAYIKSSVKDLKPVTSKKVVPINRKT
NHAVTHTYKHNLTTKVKNGPTVIVELDTPKHLDTDLFFENIRKLDEANIDAVTLADNSLA
TVRISNIAAASIIRQRYDIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGASNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKIAAGMSYFITQPVYSKEKIKEVYEATKYLNTPLFIGIMPIVSYNNALFLHNEVPGI
KMSEDILNQFKAVKDNKEKTKALSLRLSKELIDTVHEYFNGLYIITPFQRIDYSLELAAY
SKAITQNKEAIS
>A0A2V5RTS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRANSPTFSFEFFPPKTPEAAEVLYQTIRDLESYTPHFVSVTYGAGGSTRDLTH
DLVERIQQTTKLDPIPHLTCVCHNEEEIEAILLRYAKSAIGNILALGGDRPAGIAYDKSR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDYFKAKVDAGA
EYIVTQLFFDNRDFLDFRDRCALDDIHIPIIAGVMPITSVSGFKRIAELAGGARFPARLL
RALQRCQNDPEIVRRAGIQYALEQCQDLLDNDVAGIHFYTLNRSDATRVIFDSLALPRHR
NAQASGG
>A0A8D1YU06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MDRPKAKCLPAGQCCPSLGVWALEAGISRSSVPPAIRSSAMVNEPRGNGGPGPRCEGSSS
GSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRFD
RMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEVTGY
LHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKGH
PDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACSEMGITCPILPGIFPIQG
YHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFY
TLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQELTSEESVFEVFAHYLSG
EPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGWG
PSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKVGASLGHRVRGRHIYAT
IRQSRSAPPIQALCQTDTQTEPGPCPLRAPSLAREAIRG
>A0A2V6LFM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMREDSPTFSFEFFPPRTPDAAEILYHTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIEAILLRYAKSAIGNILALGGDRPRGIEYDKSR
DSFQHAIDLVKFIRRFNEAGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVGAGA
DYIVTQLFFDNRDFYDFRERCALADIHIPIIAGIMPITSMGGFKRIAELAGGARFPARLL
RALQRCENDPEMVRRVGVHFALEQCHDLLDNNVAGVHFYTLNRSDATRIIFDSLGIPRRR
NAQAQTV
>A0A2D9DD60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zunongwangia sp|TrEMBL
MKVTEHIENAKGKTLFSFEIVPPQKGKNIQELYDNIDPLMEFNPPFIDVTTSREEHIYIK
REDGLLERKITRMRPGTVGICAAIKQKYDVDTIPHVLCGGFTKEETEYVLVDCHYLGIEN
VMALRGDAMKHQRYFEPTTGGHCYANELVGQIKDLSKGKYLNEVIDSDNHADFCVGVAGY
PEKHLESPSLETDLKKLKAKVDAGADYVVTQMFFNNQAYFEFVEKAKQMGINVPIIPGIK
PIAVKKHLQLLPHVFSIDLPQDLIDNVEACKNNKEVREVGIEWAIQQTKELKEAGVPVLH
FYSMGKSSNIKKIAEAVF
>A0A1H6QCP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yarrowia lipolytica|TrEMBL
MKISHKLEKAHAADSTPTFSFEFFVPKTSQGVNNLYDRMDRMYQLGPQFIDITWNAGGRL
SNLTNEMVATAQSALGLETCMHLTCTGMPKQLVENALQSAFDGGCQNILALRGDPPVESE
KWEAVDGGFRYAKDLVKYIKSKYGDYFDIGVAAYPEGTPEEPDVDILIDHLKEKVDAGGT
FIVTQMFYDTDNFLKWVDKCRAKGINVPIIPGIMPISTYASFMRRANWCQIQIPQDFLDQ
LEPVKDDDMRVRELGTQLVADMCQKMLDSGKIKHLHFYTMNLEKATVMVLERLNLPAQDS
AVAPLPWRPSLALGRQDETVRPIFWKNRKQSYVARTQDWDEFPNGRWGDSRSPAFGELET
YGVLLRQSPQKVLELWGEPKTVDDLKTLLVNYLNGKLASLPWSDVPISNEIETIKPQILE
LNNRGILTINSQPAVNGAKSTHPVHGWGPKNGYVYQKAYLELLVTPEVAEKLVKKLENQS
EITFYAVNKTGNLQTNAPGGPNAVTWGIYPGKEVIQPTIVEKISFLAWKEEAFRLGSEWA
KCYPAESESRKFLDDIFNNWYLVNIVHNDFHDSTGIFDLFSDL
>A0A3R6CAA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHAHATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDEDAKQLGIEWTTAQVQDLFEHGYNNVH
FFTVSAVDSVKQIAKILF
>D7VEJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum subsp. plantarum ATCC 14917 = JCM 1149 = CGMCC 1.2437|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHVDHPVYILGTIGGLAGDTDATVQR
ATPATIAANVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSASVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFIGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A024UTY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces invadans|TrEMBL
MGKIIDRLMELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPRDQLREILKNVRAAGIRNILALRGDPPIGSE
RWKPVPGGFHNAVELIRFIREEHGDWFCIAAAGYSEVHSEAWNNPNLPPSDQARQLDMIR
LKEKQDAGADFIITQFFFDVDKLLQWIRDCRQLGISIPILPGYLPIQTHNSFLKFTNWCK
TSVPPQVQEALVSIKNDDAAVKKYGIQLAVDTCKKLIANKLSLHFYTMNLARTVRAVLEG
LHLIERERGLPWGAPIMRNKDGSLEKSIEQVRPIFWSNRASSYIARTSEWDDFPNGRWGD
RTSPAYGELSEYYLAYKRPKVARDQLWGRPQTEEDVWNVFVKFIEGSVKQLPWCEQGLSG
ESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPRLM
QRLVVALADYPNLSYHAFSANGTEYTNSPGPSVTAVTWGVFPGKEIIQPTVVDTASFAAW
KDEAFELWLSQV
>A0A444GUJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. (strain K172)|TrEMBL
MLATRVEIIPTDGIVDVVNSALPAGSTVSITCLPHHGVESTVRTAIKLSELGFVAVPHIA
AKCVESREHLSGILDDCAAAGITEMFAIGGDAPRAAGAYSTGVELVRDIAELSGGSMSVG
VAGYPEGHPTINGLQLMDALLEKQEFAGKIVTQMCFSAETIHNYVALLRKEGVTLPVHAG
VAGAVPKAKLISLASRIGVGASLKFLSRKGPLARKLILGERYAPDALIQELAARPGVEGI
QLYTFNSLEALPQ
>A0A357FV85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MKTLSIKQRLATNDPLFSVEFFPPKSDATAQQLLHTAERIQAYCPDFVSITYGAGGSTRS
RTLNYARKLHKDYGYAVMPHLTCVGHSRVELKQTIAEFRSAGLKQIMALRGDPPKGETNF
TPHPDGLRYASELVQLIREVYPECELGVAGYPEKHPEAPSLEIDLLNLKRKVDAGATFVT
TQLFFDNNAYFEFVDNCRRAGITVPILPGLMSVTSYKQALRFCEMCGACIPTTLNEQLIA
AGDDKAAVEAIGIEWSYQQALELLKRGAPGIHLYILNRSGPAIALIKKLQHAGFYQ
>A0A8H4M365|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus fumigatiaffinis|TrEMBL
MEKITDKIAALPPDENYFSLEFFPPKTQMGFSNLTARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCLGVAAYPEGHPVDSYQDVQDPVRDLPYL
VEKTLAGADFIMTQLTYDIDAYTKFEQMLRNHESGAFKTIPIIPGLMPIHSYKILTRTTK
LSHVKVPPQIMSKLEAVKHDDDAVKRIGVDVLSGLVEAIKEIPCPGFRGFHFYTLNLEKT
VSFIIERCGLIPDYPEDTNAVVDDDYTTAPTGAQNRSLSRRRASSVNSLPHNRVIVDRLQ
VPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQISEGQGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVSGAVARRIWGYPVSREDISTLFRRHVSGDLYIVPWSEGGAEENSS
GLNAETEVIRPELLKLIDSKGWWTLASQPAVNGVRSDDATFGWGPPGEGFVFQKPFVEFF
CPSKDFQTVLKPLFAKHGHEKLAWFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWG
VFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRVYPRGTPTERLLEEVKNDVWLVCVVG
QDFGAGTENGSEEEQQETKWMWNVLINTQ
>A0A2E7NLQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MRTLPEIYCDTSSVSRLPVSVEIFPPKTSDGDQALFDTLDLLVTYRPAFVSCTYGAGGST
RDRTLELCQEIESRYDTVAMAHLTCVGSTRDELLEWISRVRDIGICNIMALRGDPPRGTD
SFAAVSGGLEHANQLVDLIRSQGDRLGVGVAAYPEVHPEAVNAAVDLENFKRKIDAGADA
AFTQLFYINENFLRFRDRCQAEGISVPLIPGIMPITGYSRIQRIASLCGAQIPVELAKRL
EAVQDDREAELAVGVDYAIEQCRELISEGVPGIHFYALNRSQACARILDALGHGASPELS
GEH
>A0A291E4J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cedecea neteri|TrEMBL
MSFFHANQREALNQSLAEVAGHIHVSFEFFPPRSSEMEQTLWKSIDRLSILKPTFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGSGKPDMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLLSLRRKIEAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFRQAKKFADMTNVRIPSWMAQMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPKL
>A0A009SU20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 99063|TrEMBL
MSHISPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEHFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KKAKSFLIKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQVGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVK
TGKEFTPEITRFSCQPTSKQLIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENSAVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILREKLIPTVPLETRGTSSWKNWYLATEA
>A0A3W0FJ42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Litchfield|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A174LG20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum hallii|TrEMBL
MNTMQTNPQDILKTLSLSFEVFPPKKWEDFPGLYETLDELKGLHPEFISCTYGAGGSNSK
KTAEIASHIENELGIRSIAHLTCAALTEDKLLSTIENFKNAGIHSVLALRGDKPFDMSEE
DFANRQYKHPSEIIPILKKAGFRVAAACYPEKHYEAPSMEEDLHWLKHKVEQGADALISQ
LFFDNDAFYRFMDAADQKGITVPIHAGIMPITSAKMINTTINLSGASIPKALSDLIATYG
ENPSDMRKAGIEYAARQINDLAEQGMHYVHIYTMNHSETAKEICGLIK
>A0A553DK57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium aurimucosum|TrEMBL
MSPRLSASAPLDQISEDTPKRPQRTALSFEVIPPRHDADAKKIDRLLDTLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTEEELVGWIDTLVDAGVRGLLALR
GDLPEGGMPEGHLPHADSLVRLIRRWESARVARLAAGRLAVGVACYPNGHAESATADEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPPHVLDQLAAATSPEEEKEIGMQLTASLAKSVMNAGADGLHIYTHNNPDITTDLL
HRIGVTP
>F0L812|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium fabacearum (strain H13-3)|TrEMBL
MLRSETARHNGEIRGDIRLSFEFFPPKNPEMENQLWETVAELKKWDPDFVSVTYGAGGST
KAPTLDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIG
TDYRPHPQGYENAAALVKGLRDISDFEVSVSAYPEKHPESASDAVDIDMLKRKADNGATR
ALTQFFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPSFLDERF
AGYDDDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSA
A
>A0A1J3GZ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noccaea caerulescens|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFGCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIADNGLASNEAYQSDLEYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTK
IPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANIFRTKEDVRPIFWANRPKSYISRTKAWEDFPQGRWGDSRSA
SYGALSDHQFSRPKARDKKLQQEWVVPLKSVEDIQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLVKINSKGFLTINSQPSVNAEKSDSSTVGWGGPGGYVYQKAYLEFFCSKEKLD
AVVGKCKTLPSITYIAVNKGDNWVSNTAQSDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFETWSRSWGNLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIFGVFADL
>A0A1X7EZI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia filamentosa|TrEMBL
MGLLEDLQSKILIGDGAMGTLLHAHGIDNCFEELNITKPEDIFNIHKAYQKAGASVIQTN
TYGANFPKLKRYGAEEKVKDINIEGVRLAKKAVGDSGYVLGTIGGIRSFQKSIISLEEIK
RSFREQLFWLLSEDVDGLLFETFYDLEELKTVLEIARHETDKPIVTNVSLHEKGVLQDGT
PIVKALKILEELGADVVGTNCRQGPYHMLEILEEVPLLDKSFLSAYPNASLPQYVDGRLI
YETDPDYFYKTALAFKDQGVRLLGGCCGTTPSHIEAMAKALKNAVPITEKTVKEAPPIEV
LSQEIQAQPHLHEIVQEKHSIIVELDPPKKLGVDKFLKGAHALQAAGIDALTLADNSLAS
PRISNLAMASLLKDQLKTRPLIHLTCRDHNLIGLQSHLMGMHTLGFNQVLALTGDPSKIG
DFPGATSVYDLSSFDLIRLIKQFNEGVSFSGKPLGQKTNFSIAGAFNPNVRHLDRAVQRL
EKKVDCGADYFISQPIYSIEQLEDVYEATKSLKAPIYIGIMPLTGAKNARFLHHEVPGIK
LSENILTRMEKIEHDKEQSAKEGILLAKELIDRAYELFNGLYLITPFMRYEMTVELANYI
KAKELVSIERKI
>A0A7Z7QRK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus schleiferi|TrEMBL
MSRLLKALQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVEHIHRSYIEAGADVIQT
NTYGANFEKLQPFGLEHKVKAIHQAAVAIAKRAARPETFILGTVGGFRGVKQGELSLSAI
QYHTEIQVDTLIESGVDGLLFETYYDLTELIRVITQTRQNYDIPIIAQLTASNTNYLRDG
TEINDALQQIVAAGADVVGLNCHHGPHHMKHSFSHIALPDKAYLSCYPNASLLDLDQHTF
QYSDNAQYFGDTAQQLIQEGVRLIGGCCGTTPEHIRHIKSAVKGLKPIQNKKVIPIDKKR
ETLAQNQHQLNLADRVRQKPTIIVELDTPKHLDTTKFFNNVKALDEANIDAVTLADNSLA
TVRISNIAAASLIKQRFGIEPLVHITCRDRNLIGLQSHLLGLSLLGIHEILAITGDPSKI
GHLPGATNVYDVNSKGLTELALKFNKGINTDGDALKTTTQFNIAGGFDPHVRNINAAVRK
METKIESGMSYFITQPVFSKEKIIEIYEATKHLNVPIFIGVMPITSYNNALFLHNEVPGI
KMSEEILEQFKAVAGDKEATYQFSISLCKSLIDTVHTYFNGLYLITPFERVDYSLELAAY
SKSITQTHQEAIL
>A0A2E9P746|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTFDAKASLKGWSIEITPKESNTISCFSAFLEKGTKVNVTSLPKTSVRDTLTAVEKLKR
DGMNPIPHITARTTADEGDLARVVEKYADLEISEVLIIAGTKDQPAGRFSSSADLISSGV
FEHFGIINIGVAGHPEGSPDITEQQLQDALDQKNHLAVSRNLNIFLETQFCFDAQRIINW
EKVIRDRGNMLPIRVGVAGPTKFLSLINFAIKAGVGPSLKFLINERDKLTKLVNSYDPTE
LICSLAPQFSPEANTCFESVHFYAFGGFRKTAEFAQELFK
>A0A0Z8C8C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPATYLTKEKVRSVLHSLDEIDVHQILALRGDIIEGLLPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARTIHQATHSLFKHYS
>A0A1V0DUB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria lactamica|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A081LNA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas caviae|TrEMBL
MGFHSARQVEALNQSLADLGGDISVSFEFFPPNSEGMENTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLENDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQA
>A0A5C4WC01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea phyllanthi|TrEMBL
MALGRPSVLPDRVPTVRDLLAAGGRSFSFEFFPPKTDEGARQLWKAIRELESLRPTFVSV
TYGAGGSTRDRTVGIVERIAHDTTLTPVAHFTAVNHSIRELRHLVGRFADAGVRNILAVR
GDPPGDPMAEWVQHPDGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIDADTEYFVQ
KCRAGADYAITQMFFRAEDYLRLRDRVAARGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPEVAARFEEVADDPEAVRRLGIEHGAELCRRLLDEGAPGIHFITFNRSSASREVFQRLN
VPSSVTAGPAGRHPLPVAGGLQGDAR
>A0A2E5UUU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSEKYQQLRDVLESGRFAITAEIPAPVSASSVEMEEKIKILKGSVHAINVTDNPGATAHM
SSLAGSAIVRNQGIDPILQITCRDRNRLAIQSDLMGASALDINNVLTLAGDPVKNGDQKD
AKAVFDINSKTILSIMDVMNVEGKTMSGKELQTKSNFFPGGAAILHEPEENWDPKALNEK
ASFGARFIQTQFCYDVELVKKYMQRIVETGLSEKLYFIIGIGPLRSDKSAKWMRDKLFGT
VIPDSIVTRIESAGDQIQEGINICAELIESFQEIEGVHGAHLMAPRNLSAIPETVKRSGI
SI
>A0A497DWY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MSGFKEFFAEADFVLFDGAVGTQIYARGVPKGHCYDELNLSLPETIQEIHREYVEAGAQV
ITTNTFGANAFILEEYFALGDKTREINYYGARLARQAVRGRAYVAGSIGPVTRPLDTDKK
IDFQDLRAIFQEQIEALLEGGVDLLVLETFADLDELLLAIQVARQVAPDIFILAETSFPN
NGLTLFGKNPYEVGFALEKSEADALGSNCGTGPQSVLETIKKMARVTRKPLSAMPNAGLA
QFVNGKFYYPFNPEYFVRYGQKLLQAGVKILGGCCGTTPEHIRRMAAELKGLKPRSRSLS
LIGPVTTTAPKVYKERIETQYKTQVEKGWAVSVELDPPKDPNIDKFLKKIERIAPYIQAY
NISDCPMARARMSSIATGNIIQQQLQKEVVIHYTCRDRNILGIQSDLLGAAALGLNNILT
LGGDPPAVGDYPFATGVYDLTTEGLVQLCSALNHGRDLLGNPLGRPTHFYIGVGYNINDQ
SLPAFNSLVKKINQGAHFVVTQPVFNLASCWPRLEELKKKNIPVIVGALPLTSFKQAEYF
HYEVPGIIIPEKFLARLEKLKAKEAEKEGVKITIELINELKPAINGILLMISFNKLYLLE
EIMAKI
>A0A2H3T9Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A420PDW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDRIKAIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASSELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A0N0VBU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARTIHQATHSLFKHYS
>A0A411GMR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A2J8USM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pongo abelii|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYE
EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNAREMEAP
>A0A023Y6K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas rhizophila|TrEMBL
MTAISFEFYPPKTDDQRAQLDRTAAKLKAFAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASDLISFI
RAEHGDAFRIEVGAYPETHPQANDALLDLKHFKTKIDAGADAAITQYFFNADAYFHFVDA
VRALGVTVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDAESVRAFGAEVV
AGLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLKG
>A0A364LP53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus flavus|TrEMBL
MHIKEKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAAEGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLLPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIKDLSRLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLIE
LNNRGILTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDSWYLVNIVNNDFHNTYDLFELFKDLNVRDFDVEVAADNADLK
SQENETAETTAN
>A0A6I3ANJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNSKLRGTTFSLEFFPPKDEAGESRLWLALSQLQPLAPDFVSVTYGAGGSTRDRTIRVTS
EITKRTSIPTVAHLTCVGATRDELVEILNQFKNSGIDSILALRGDPTGGPTAPWQMIPNG
LNYAKELVELAVGMGFKAGVGAYPDGHPASNHDLAKDIEVLLAKEKAGATFATTQFFFEI
DKWQAIVDKLAKAGSKLPVLAGILPITNVKQLNRMAELSGMKVPTAIADQFNKYADDLEA
TKEIGIEIATNLGAQLLKRGVPGLHFYTMNSAQSTVAIAKNLGLIK
>A0A6A6YA74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mytilinidion resinicola|TrEMBL
MHISQMLEQSRRKNKATFSFEFFPPKTAQGVQNLYDRMDRMHSFGPAFIDITWGAGGRMA
RLTSDMVKVAQSAYGLETCMHLTCTDMEKSKIDEALKEAYKAGCTNILALRGDPPREKEK
WEATAGGFRYAKDLVKYIRDTYGNHFDIGVAGYSEGCEDQDDHELLLDHLKEKVDAGATF
IVTQMFYDVDIFLDWVDKVRAKGVTIPIIPGIMPIHTHAAFMRRATWTKCNIPTAWTKAL
EPIKNDDAQVREVGKTLIAEMCRRLLEAGILHLHFYTMNLAQTTRMVLEELDLMPDMESP
IEKPLPWRPSLGLNRREENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDARSPAFGELDA
YGVGLKGTNEQNIKLWGSPTSVKDIANLFVRYMSGKLDSLPWSEAPISKEAESIQDDLVN
LNTRGFLTINSQPAADGVKSSDPVLGWGPHNGYVYQKAYLEVFVSPEYIAEVITRIERDP
DITYYAVNKSGDLKTNAPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFFRLGQDW
ANCYSSVSPSRYVVEDLMDTWYLVNIVHNDFHVPHGIFPLFNGLEVEDMEKPLHSTGIVN
GDEKPTESSKPTTNGAAAHTNGVNGHEQKN
>A0A484ULC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|plant metagenome|TrEMBL
MGVAVVRKPALHACYSMEVSAKDIPALTEVAPRLPPASTIAIPYLAGEGNEARLAAARAV
RELGFAPMPHISARRVASLAELHAFVERAAAEAGVERCFVIAGDPSTPKGPFPDSFSLID
TGVFERAGIKAIGVGGHPEGHPVMSVADRWEVLERKCRSIERRGMAPSIVTQFVFDADVV
LTWLEALRARGIAHPVRVGVPGPAGVAVLARYAAMCGVGACASMLSKYGISLGKLLGTAG
PDRFVDRLAAGLTQAHGTVSLHFFPFGGIAQSVRWIEQYRAR
>A0A2S7SIC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia fergusonii|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0B0HCE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solemya velum gill symbiont|TrEMBL
MTAQDNTKQFSFELFPPKTEKGIEKMRQTVTQLNLLKPAYFSVTYGAGGSTQSTTFAAVD
WLRSEEIETAPHISCIGASKDEIDSLLQRYIGQGITRLVALRGDLPSGAGLGEIHDFSHA
DELVAYIRETTGDHFHIEVAAYPEFHPQATDPFKDIEYFANKVSAGANAAITQYFYNADA
YFRFVDACEALNVTVPIVPGIMPITNYSSLARFSDSCGAEIPRWIRRRLEAFGDDTNSIR
SFGADVVSDMCERLIANGAPGLHFYTMNQAGATQILCDRLGITG
>A0A6A8MQ54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSDLLSQGTSVSFEFFPPQTDEAEEVLSRTIGELESLHPSFVSVTYGAGGATRERTHDLV
VEINQKTSMTAMAHLTCAAHSRTELVDIISRYRDAGVENILALGGDLPNDSDLSAGELEH
ALDLVRLIRATGDFSVGVAAHPEPHPRSPSLAQDRDRGAEKLGEADFAITQFFFETRHYF
DLVEDFRARGVTTPVIPGIMPVLSIAGTKRMTELQGSEFPQWFLDRLRLVEDDPAAVRAT
GIEEATRLCQELLDGGAPGLHFFTLNRSTATREIAANLGLPN
>A0A6M4Z500|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas media|TrEMBL
MGFHSARQVEALNQSLADLGNNISVSFEFFPPNSEGMENTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNFQTLNKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQA
>A0A078BEG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomonas sp. CB2|TrEMBL
MRMASAQSVSPRVNLSFEFFPPKTPEGADKLRAVRQRLYARQPEFCSVTFGAGGSTQEGT
LQTVRGILAEGVDAAPHLSCIGASRDSVRGHLRDFQAAGVKRLVALRGDLPSGYGIGGEF
HHASDLVAFIRDEMGSAFHIEVAAYPEMHPQARSPLDDLQHFADKVRAGANSAITQYFYS
AAAYRRFVDDVRALGLDVPVVPGIMPITNSSQLLRFSEVCGAEIPRWIRLRLQSYGDDRE
SIRAFGREVVSSLCEELIASGAPGLHFYTLNQAEATLAVLDDLGR
>U5H328|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbotryum lychnidis-dioicae (strain p1A1 Lamole / MvSl-1064)|TrEMBL
MSRRITDKISSLGPDEPFYTFEVFPPKTSPGVSNLISRLSRMSSLNPSWIHVTWGAGGST
HSTSLQLAEAIVSKTNGLGLDACLHLTCTNMERSVLDEALKRAKELGVVNLLALRGDPPR
GEEYWVASDGEFQHATDLITYIKEHHENDFCIGVAGYPEGHADSADKSADIDYLYAKQQA
GAEFVVTQLFYCVETFLKWHKACRDKGITIPILPGIMPIQNYQSFRRMTNLCKSHIPPQI
VKDLELIQHDDQSVKDYGVRLAVSMMREIWHAGIRGYHLCTLNLEKSVSRVLEQLDWVGH
PLASPLIKESRANGVDASKSSSLLPSQVELLRGKGSKGGVDGQGARKDSPTSWDEFPNGR
FGDARSPAYGDLDGYGVGLKLTPAEALRQWGSPTTLADVSKIFSSYLSGKQASIPWSEEA
LRAETKTITQHLIRLNDERHWWTVGSQPAVDGAPSGDPVYGFGAKGGYVYQKAFVEFFLT
EAELDQLERRAEEDAKARKEKDEGEGLIKWYAGNRAGKLRSNMKKDNVNAVTWGVFNAQD
IVTTTLIEEMSFKAWSEEAFAIWLEWSHLYPANSASRQFIRELADTRWLVSVAHHDYKQI
DGLWQWLLAAPKI
>H9FUQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macaca mulatta|TrEMBL
MVNEARGNDSLNPCLEGSASSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDLCVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYE
EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDALELLNRPTQNERETEAP
>A0A231VN52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterium thermosaccharolyticum|TrEMBL
MLNSKNLCQKLNNREFVVTVEMSTPKGADISNSIEEARKLYGIVDALNITDCPMANMRMS
PIALAHLLQNHLNIETIFHLTCRDRNLIGLQAELLGAYALGVRNILALTGDDPKRGDVPQ
ATGVYDVDSIGLIKIAKSLNNGFDYSGNRLESSTSFCIGTTANPNDLSKESIEKLKIKIE
NGASFIQTQPVYDEKILYRFLDAISKFGIPVLVGVLPLKSYKMAVNLNAKVPGIEIPDYI
LERLKNNGKGEGLKIAVEFINKIKNLVSGVHIMPLGRTDIVVDIINNVKNIKTDIKKEVL
>A0A3E4Q2D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea formicigenerans|TrEMBL
MTCKIRDILKDQTPQVSFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKN
TVSIASHIKDDFGVTSLAHLTCVSSTREEVHRVIDKLKEKNIDNILALRGDIPKDNAFPL
PNQYRYACELIEDIKQQGDFCIGAACYPEGHVETEHKKDDISNLKTKVDCGVDFLTTQMF
FDNNIFYNFLYRIREKGILVPVLPGIMPITNKKQLRRSMELSGTAVPQRFLAIIDRFGDD
PEAMKQAGIAYATDQIIDLIANGINHIHVYSMNKPDVAAAIMNNLSAILKVED
>A0A170GFF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A3M6W8P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMNYDAEIFIEWAKKVRAAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAELFVKYMSGKVETLPWSEQPISPESNVL
TNDLVNLNSRGLLTINSQPAVDGMKSSHPVYGWGPNNGYVYQKAYLEVLIPPSLIAEIIR
RMDANPDITYYAVNNSGELKTNAPQDGGPNAVTWGVFPGKEIVQPTIVETISFLAWRDEF
YHLGSEWAKCYDEGSRSKNLIKEITESWYLVNIVDNDFRNMRGIFPLFDGLKVEGVEPVA
AVNGVAGVNGDAKGDVEKKEESRKPEVNGVPDGNNAVNCADGAAVNGQVKN
>A0A534JTM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MPAEVASRAIRAGSRLERILASGEFAVTAEIAPPASVDASEIRRHASLYRGTVDACNLTD
GQRALVRISSMAAATIALQEGVEPIMQMVSRDRNRIGLQSDLLGAAALGIRNVLCLWGDP
PTAGNEKEAKAVYDLSTEEMISTFRALRDTGVLRGGEMVEQAPKVFIGAAADPFRGSKED
SFGKLRGKVTAGADFVQTQGVFDVDAFEEWMRLVRKEWLHDKVFILAGVIPLKSVKMARF
MVEKLGAVVPKHIVDRMERAPNPRSEGVSIAVRTIKALKKIEGVHGVHVMPIGWEEIVPE
IVKDAGLFPRPELAA
>A0A150TUV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
MVSKSKMERLLSERQFLVSAELTPPRHYDLEKLLKHARNMAGCVDVVQINDHLLSQARCA
NMAVGHFVKQEGLEPVLQFSLRHKNRIALQGDLLGMAALGLSNIIILGGYPCAIGSDPEA
KEVSDVDSYAAIELTRRMTREGRLYNGDVISPAPYFHVGTIDFPCGEQAIAGAMDRLSAK
IDAGASFIQVQAVFELAPMRRWMAAVVERGLHERAHFIAAIFPFAGVDRLSFLQKVPGLV
VPEHLIERVRQSGDAEGESYRITLELVRGLRDVPGLSGIHMRSIGAEDWVPRLVEEAGLR
RAA
>A0A0V7ZQX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mastigocoleus testarum BC008|TrEMBL
MPNTHNQIPLTCFRKAVEAGEFLVTAEVAPPKGGNPQHMINMAATLKGRVHAVNITDGSR
AVMRMSSLTASVILLQHGIEPICQVACRDRNKIGLQADLMGAHALGIRNILALTGDPVKV
GDHPDAKGVFDVESTRLLQIIGKLNKGIDYNEKPLPDGATDLFAGAAVDPQCRSWSGLQS
RFERKLKSGAQFFQSQLITDFERLDKFMTQIAAGSNKPILAGIFLLKSAKNARFINRAVP
GVNIPEHIIDRLERAKEPLEEGMKIAAEQVVIARQLCQGVHMMAVKREDLISPILDMAGV
KPVNNEIVAA
>A0A3A3KR87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella montevideo|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1B9DN38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium glycines|TrEMBL
MKVTEHLEKAKGKPLFSFEIVPPQKGSNIKDLYANIDPLMEFKPPFIDVTTSREEYVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGVDAIPHVLCGGFTREETEYLLVDCHYLGIDNL
VALRGDPMKGEKYFEPTVGGNHYAVDLVRQIKAMNNGKFLHGELPLENAPDFCVGVAGYP
EKHIEAPSLEADLKRLKEKVDAGADYIVTQMFFDNQRYFRFVEAARAIGINVPIIPGIKP
VAVKRHLQLLPQVFWLDMPEELIHAIENAKDNAAVRQIGVEFAIQQSKELIEFGVPCVHY
YSMGKSDNIQQIASQVF
>A0A536L621|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIAEMLTRSKPTISFEFMAPRNESEVDVLEQTVSTLAGHAPDWVSVTYRVRTGDKTLEL
VTRIKRQYHIEAMAHLTCANSADRTRQILNWMEREGVANVLALRGDDPAAGQRFVPADPQ
LAHASDLITLVKRSGYRFGVGAACSAEKHPESPTLDHEMRYMRLKVECGADFLITQLFMD
NAFYFDLVRRARDEGITVPIVPGLMPIASRRSLGVMTAMSGASVPAALQAAIDEAPDDEA
IRALGVRHCIAQCAELLEAGVPGLHFYTFNRARAPIEILEALRGQQLLAS
>A0A536QX48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSSLASLLRSGEFVVTAELNPPKSAAAGVVRRRAEALKGVVDAVNVTDSNRAMVAMAAIP
AATIVRSVGLEPIVQMTGRDRNRIALQADVLGAAAIGIENFVFMSGDDPKQGNHPDAVFV
KDLDGVGLVKMAVGMRDGGQFLSGDEIKQPPKMLVGTTASPFTKPMEADVTKTLEKIAAG
ADFLQTQPVFDLATFSRWLVEVRRSASREVPMLAGVLILRSPDQAERLARVPGLAIGPEV
LDRLKKAADAEAEGIAIAVQMVKALKALPGVRGVHLYAIEWPEAVARVVEAAGLLPRPDA
RVPA
>A0A5V7UH54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella newport|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKESTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A074PT96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A535LR76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MIGFLQAPRYEVLPTEEVENLVTAHVPREVTITITASPRRGIESTIGLAERLAANGYQVV
PHLSARLIRDQAHLREILARVTALGRGEVFVVAGDAKEPAGDFPDSVSVLTAISAEPHGL
REIGVTGYPERHSFIEDDLTIQAMWDKRRIATYIVSNLCFDPRLVKKWVARVRRRGVELP
VHVGLAGVADPAKLLRVSTRIGLADSARFLRGHSNWFMRMLQPGGYDPERFATGLLPDLA
APERKVAGLHFFTFNEIEATEHWRQETMARLLAA
>A0A661IBB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSSSRLERILRAGHFAVTSECGPPRGADPEAIRKKGELLKGVVDAVNVTDCQTAVVRMS
SLASCLILKEMGFEPILQMVTRDRNRIAIQSDILGAAALGINNILCLTGDHQRAGDHPQA
KNVFDLDSIQLIAAVKTMRDEGKFINGEELTVRPRLFIGAAANPFADPFEIRALRLAKKV
AAGADFIQTQCIYNLERFREWMRQVVDMGLHEKVYILAGVTPLKSVGMARYMKNMVPGMD
VPDEIIARLKGVPKEKQASEGIKIAIETIEQLKEIEGVRGVHIMAIEWEEKVREIAEGAG
LLPRPQVQ
>A0A1B2I1Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cloacibacillus porcorum|TrEMBL
MKNFFKLDKPTFSFEIFPPKGAGDLSQIFSTVDALASLDPDLISVTYGAGGTSRENTAEI
ASRIQRDYAIPALAHLTCVGSTREEMRATLDKLKEKGIQNILAMRGDINNEGTKDFKYAS
ELIKFINDNYDFRVFAACYPEKHLEAYSMQEDLEHLKAKCECGVSVLISQLFFDNASFYS
FRERARKLGVTTPIEAGIMPITSPTQINRMVSMCGASVPEGVQKIIRAYGHNSMAMREAG
IAYATNQIIDLLAEGVDGIHLYTMNQPDIAKRICENIRGVLYSLRVKRG
>A0A3T3D7U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella newport|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A661SDL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTFREALESGKFVVTAEVGPGKGTDVEHLLKDAAIIKDRVDAINVTDLQSSVMRLGSMAF
CHLLTDMGIDPVFQLTCRDRNRLALQSDLLSAWVLGIRNVLALTGDHPVLGDHPGAKPVF
DLDSVSLLEVIGKLNSGFDMAGNALKGAPDFLAGAVVNPGADNDAALDLQIMKMEKKIEA
GAKFFQTQGIYDLDMFEKFMKRVEGFGTKVLGGVILLKSVGMARFMNRNVAGVFVPEPVI
QELKKAEDKSEASINIAVRLVKGMKDLCHGVHIMALGWESKIPPVLDAAGL
>A0A1U8C7Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesocricetus auratus|TrEMBL
MVNEGSSSGSESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGA
VNLISRFDRMAAGGPLFLDVTWHPAGDPGSDKETSSMMIASTAVNYCGVETILHMTCCQQ
RQEEITGHLHKAKQLGLKNIMALRGDPVGDHWETEEGGFDYATDLVKHIRSEFGDYFDIC
VAGYPKGHPEAESFEEDLKHLKEKVSAGADFIITQLFFEANTFLSFVKACTEIGISCPIL
PGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSG
LVPGLHFYTLNREVATMEVLKQLGMWTEDPRRPLPWAVSAHPKRREEYVRPIFWASRPKS
YIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELSSEESVFK
VFEHYLSGEPNQHGYTVTCLPWNDDPLAAETSLMKEELLRVNRLGILTINSQPNINGKPS
SDPVVGWGPSGGYVFQKAYLEFFTSREIVEALLQVLKKYELRVNFHIVDVQGKNITNAPE
LQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIH
DNYFLVNLVDNEFLLDNCLWQVVEDTFELLNGHSTRGEAQAP
>A0A104NZI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia territorii|TrEMBL
MKSIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDNLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAAAATRTICERLTM
>A0A1Z1SRZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus mirabilis|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTQEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHAIIKDIKERTGLEAAPHLTCIDACREELQHIAQDYWQSGIRHIVALRGD
LPDNSQKPDMYAVDLVHLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKKKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMFD
GLDNDPETRALVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPQLAKV
>A0A0S3ALH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas ureae|TrEMBL
MDSQKKFSPTFSFELFPPQTPQGIEKLRLTRQQLAQFNPKFFSVTFGAGGSTRERTFETV
LEIQSEKHVVAPHLSCIGSTQENIRIILEKYYEIGIRRIVALRGDLPSGMAQAGEFRYAS
ELVAFIRKEFGSSFHIEVAAYPEYHPQARSAQADFENFKRKIETGANSAITQYFYNTEAY
FHFVDSCEAAGLSIPIVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLEGYSDDSASIQA
FGLDVVTDLCERLLKAGAPGLHFYTLNSANLTSIIWQRLNLKEYVQ
>A0A379KGI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAGCNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKDELRALLAQYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFETDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLAIWNNLKLPR
>A0A2E9CVC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp|TrEMBL
MSLPSIHPNWDLPPKGMTDGYSLEITAKDIDALREAAPAMAPETPVAVTFLPGESLEARI
EAARTVRALGFEPMPHFSARRLESGDDFEAYLAAVVREAGVTRCFIIAGDPPEAAGPYSD
SMSLIRTGAFERAGIKAIGVGGHPEGHPNMTPDQCFDILIAKCAEIEARGMAPLIVTQFS
FDAAPVLSWLEELRGRGIDAPVRVGIPGPAGIKTLMRFAARCGVGASASVLTKYGISITK
LIGTAGPDKLVDALGKGLGSQHGKVRLHFYPFGGLARTVEWINNYTKSR
>A0A6B8IZF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDHGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGAEVV
AKLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQG
>A0A6P7R6F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mus caroli|TrEMBL
MVNEARGSGSPNPRSEGSSSGGESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFS
LEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPVGDHWEAEEGGFSYATDLVKH
IRTEFGDYFDICVAGYPRGHPDAESFEDDLKHLKEKVSAGADFIITQLFFEASTFFSFVK
ACTEIGISCPVLPGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIEL
AVSLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWNDEPLAAETSLMKEELLRVNRLGILT
INSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLNRHPTERETQAS
>A0A7X3PFI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MSDRLREWIEGDGIHLIDGAMGTVLYESGVFVNQCYDELNLTEPDRVLGVHADYVRAGAQ
LIETNTFGANPVKLEPFGLEPSAHEINVAAARLARQAAGGRAAVLGAMGPLGIRIEPWGP
TSVDEAADLFGRQVAGLAEGGVDGFMLETFSDLDELLQAVRAVREVAGAAPVFAQMTFGD
AGHTEYGATIEAAAAALERAGADVIGLNCSVGPSSMLFGVERMVAATSRPVSALPNAGLP
RDIGDRKIYLASPEYMARYARRMAAAGARFLGGCCGTSPDHTRLTATLLGTNGPGPARVS
VARPGEADGRAATEPPPLAGRSALGRRLASGEFVGAVELTPPHGWDPGELLAGAGRLRDA
GVHTVHIVDGPAHRSRIAALPAAIVIERELGMETVPHYSCRDRNMLGMLSDLLGAAAAGL
RNVFLITGDPPRGGPYDTGGVYDIDSIGLTNVVRQLNLGLDPGGSSIGAPTSFVKGVAVN
PGAVDPEEEVRRFAWKAEAGADFAVTQPIFDREKFLAFAREIEDFGVPLLVGLWPPLSLE
NAEFLAHEVPGVDVPLDVLERMAGAQARGAEAAAREGVAVAREVLEAVRPHVAGALISTP
GNDVDRAAAVLEG
>A0A0H2WU94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella paratyphi A (strain ATCC 9150 / SARB42)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>I7KJD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium otitidis ATCC 51513|TrEMBL
MSTAFHYTDYRAGRRSSHPTVSFELYPPRNPKRSSSIWAGVERLIAQAPHYVSVTYGAAG
STVDTRDRSVQVLMHVHDKHPELPAVAHLTCYGTSQGELVLIVRLLLRAGVRDFLAIRGD
PPADGSEKLADNGLTRAVQLVRLIRAVAADELPDGVGTGPNGSGPSTAKNPRDYVSVAVA
AYPASRGMERQNDIDALLDKQAAGADYAITQVFYDPDDYSTLVKDYTAQGGTLPIVPGIL
PLHDLKRLRAMERLAGIPVPERLLRIFEDNPPGPARVRASLQATTHLIADCLKAGAPGVH
LYTFNRPRPTLDILEYLKAAGFLTPAEETYRQLDPGAYHKLDLDTELAALSMHHMPPGV
>A0A412TAY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides stercoris|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEKNGYHHAVELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFNFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTNEILKCKNDAEAQQVGIEWCVQQCKELMKHHIPSIHF
YSIGAVDSIKEVAKQIY
>A0A3E2WF20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster aldenensis|TrEMBL
MKIRDILAQGNPTLSFEVFPPKTEDNYHTVEKAAKEIAKLKPAFMSVTYGAGGGTSDYTV
GIASDIKGYGVTPLAHLTCVSSTREKVQGVLKELKGHGIENVLALRGDIPENGQTPRVYH
YASELIREIKQSGDFCIGAACYPEGHVESANKSVDMDYLKQKVEAGCDFVTTQMFFDNSI
LYSYLYRIREKGITVPVIAGIMPVTNAKQIKRITQMSGTYLPSRFMSIVDRFGDNPAAMK
QAGIAYATDQIIDLIANGVGGIHVYSMNKPDVAGKIKENLSEILGNGCVCAP
>A0A6J6LY32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSVLREKLENTNDLVFTAEFPSVDGGGMASVVQHAARLAPWFDAVNATDNPAAHAHTSNT
TTAIAMKMHGLEPIMQIVCRDKNRLAIQSDMAGAALHGITNISLLTGDDVTAGDEPEARR
VFDVDSAQAINIARIMTTGKYLSGRTISPAPDFYIGAVENAAAPPFEYRIQRALKKHRAG
ASFLQLQICYHPDRLEAFCKGVAEVAPDLKLIPTLVLVKGSRGLAFMNDKVPGIDVPAST
LARVQNASDPSVEVNKLTLELAKHALSLPGVRGLHITDFRHDDSLNTFMNDLGRTPNR
>A0A6J6RCM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSVLREKLENTSELVFTAEFPSIDGGGMESVVKNVARLAPWFDAVNATDNPAAHAHASNT
TTAIAMKMHGLEPIMQIVCRDKNRLAIQSDMMGASLHGISNISLLTGDDVTAGDEPEARR
VFDIDSAQAINIARIMASGTYLSGRKINPAPDFYIGAVENAAAPPFDYRIQRALKKHRAG
AQFLQLQICYHPDRLEAFCKGVAQVAPDLKLIPTVVLMKGARGLAFMNDKVPGIDVPADT
LSRVQNASDPSVEVNKLTLELAQHALSLPGVRGLHVTDFRHDETLDTFMSDLGRTPKRQG
>A0A6J1FQ74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cucurbita moschata|TrEMBL
MKVIDKIRAATTGDDARVVFSFEYFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGS
TADLTLDIANKMQNMICVETMMHLTCTNMPIEKIDHALQTIKSNGIQNVLALRGDPPHGQ
DKFVQIEGGFACALDLVKHIREKYGDYFGITVAGYPEAHPDVIGSNGVATLEGYQSDLAY
LKRKFDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTEFCK
TKVPDEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILM
SLGLIEESKISRSLPWRRPTNIFRVHEDVRPIFWANRPKSYISRTIGWDQYPHGRWTDSR
NPSYGALTDYQFMRPRARGKKLLEEWALPLNSIEDVYEKFMKYCLGKLRSSPWSELDGLQ
AETRIISERLGKINMKGLLTINSQPSVNGERSDSPSVGWGGSGGYVYQKAYIEFFCSKEK
LDAVVDKCRALPSLTYMAVNKEGVWVSNITQKDVNAVTWGVFPAKEIIQPTVVDPASFHV
WKDEAFELWSRGWASLYPEGDPSRKLLEEIQSSYYLVSLVDNDYVNSNIFAALEDF
>A0A087EM56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia acidovorans|TrEMBL
MSFPISFEFFPTKTPEGAAKHVQVRKNLYARKPQFCSVTYGAGGSTQAGTFNMVRDIQSE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPHSDLEAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>R1DH75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emiliania huxleyi|TrEMBL
MSSTDTAGNPTDCRGQLPAVKNGKIIDMVNAWTAATDQPFISFEYFPPKTPEGVVKLHKV
IDEMCKQKPLFVDFTWGAGGSSADLTLELSKTSQQKHNVMVNMHLTCTNQSKEVCDAGLA
GAKEAGICNIVALRGDPPKGQDKWEVTEGGFACALDLVKYMRTNYGDYFSIQVAGYPEGH
PDRITKAGGEWSVVSEMSRPLSDREKMRLVDVDGERMTGFCKTRIPPAMAKRVAELSGDD
KKAEFAEYGIDYLTDLCKQLVASKLVPGLHFYALNQSERTFQILKRLGYYAPTD
>A0A6J6W308|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVVRTSYSLEFFPPKDGEGEARLWDALESLKRINPTFVSVTYGAGGSTRNRTIGVTEEVT
HRTNFPTVAHLTCVGSSRQELISILHMYKAAGIKGILALRGDPVGGPRAPWTPTSDGFTH
ADELVQLIHEFGGFDIGVAAFPDGHPGSDGDSKKDIDVLLRKEFLGAQFATTQFFFEVSK
YEQLVDGLQARGSSLPIIPGILPITNVKQLQRMAELGGTPIPSDVAKSFGAVENDPIAVH
QLGIELASQLCEDLLTAGAPSLHFYTMNNATATLEIYGNLNSAN
>A0A6J6BX87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MAKRTSYSFEFFPPKDAEGEARLWAAMTGLEALHPDFISVTYGAGGSTRDRTIAITSHIT
ERTKIPTVAHLTCVGSTKTELIEILGKYREAGITSILALRGDPVGGPSAPWSTTPGGFDH
ADQLVELASELGGFSIGVAAFPDGHPASGGDFEKDIDVLIRKESLGATFATTQFFFEAQR
WRALVDRLSARGSNLPVIAGILPVTNVKQLSRMSELGGTAIPEAMMKRFLAVESDPEAVR
ALGVEIATELCQKLLAEGVPGIHFYTMNSSTATREIYENLGVSR
>A0A379QTF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1U7DG35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevirhabdus pacifica|TrEMBL
MPSAPSVSFEFFPPQSLDASFRLWETVQALAPLSPEFVSVTYGAGGTTRKLTHEAVETIH
KNYGLRVAAHLTCVDATREETMEIVRGYKEAGVTDIVALRGDPPKGAARFTPHPEGFASS
VELIEALAAEGGLTLHVGAYPDPHPEATNPVADVEYLKRKIDAGASTAITQFFFEKETFL
RFRDRCVAAGIDAPIVPGILPIDNWKRVRNFAARCGAFIPDWVDEAFDKADRDDRSELFA
TAMCTELCSDLIDEGVDTLHFYTLNRPYLTRQVCNALGVHSTQGLEKVA
>A0A5H8WT13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar London|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3S3FYU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFAEMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFD
GLQKDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A439Y7N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVVREFADMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKSAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHEAEAA
GSAAA
>A0A2V4DSB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNQKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHAVKHTYGIESVAHLPGINFDKAEMLKILHDLKCAGIDNVLALRGDISPNVTPKDDF
RFASELVTFIKENGDFNVIGACYPEGHLEATTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKAHDMDINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKSA
>A0A1Q5T7L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus proteiniphilus|TrEMBL
MGLLDELKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPLIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPERAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIEAMAKALSDRTPVTEKTVKRRAVSVS
VQAERPAPSPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKERLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVYEATKHLDTPIYIGIMPLVSARNAEFLHHEVPGIT
LSDEIRARMAACGDDPVQAAREGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A8B5S8G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bereziniae|TrEMBL
MAGFPACMTLSDRVRSDEDIAPLIAAQAYPDHIEKVLHYAGKGRDIDDFKLFLKQADSVG
LRDILLLTGDKLKQHHDGQGQHARTRYLESVNAVMAAHQYGGFHIGVAFNPFKYTPAEQQ
AQYLKLHKKLNAGADYIITQLGFDLSALKQLQTFLAQEKYIQKTLACVMPLTLARAQFMV
KHKVAGIVITQHMLEILTQDQVNHCPENVYKRCALQILICQHLGYAGVHLSACHKADEQM
LLEQYIEQYRDLNLSQCEILWNQLWQLAEGEQLRPKVAAKRIKSALNNKVKYQFLDLIHR
AMFQSSFMKGVGTFIFNASFWNRKTAAKVLLQTEYLSKHYLLGCESCGQCRLAETLYICP
ETCPKGLANGPCGGTDLDRCEFGDRECIHSVKSRLAHDVDQIQLLKEQLIPTVPIEVRGT
SSWKNWYKAE
>A0A816JSB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria magnacalcarata|TrEMBL
MPENGINIKTICNSSNDSVDLKRSESENGIGTTKGSSPQPVKYVSLAEKIQERISNHERW
FSLEFFPPTTSNAAANLIGCVERMAMAQPLFCDITWRSTGDPAGNKETSSMMIANTMLNY
CNIDTMLHITCCGTKKPQMVQYLNRAKEVGIRNLLALRGDPPVGEQWDPDQTDFRYATDL
VKFIREKFGDYFVICVAGYPQGHPDTESYEEDLGYLKQKVDAGADFIITQLFFQAETFIK
FEADCRAIGITCPIIPGIFPIQGHASFRSVIRLAKLDVPQEMLDSIESMRDNDEAIRDYG
VQACVDLCQKLLDSGKVLGIHFYTLNREYATTEILKTLSFWLEETPLRALPWKKTSQSHT
RSQENVRPIFWSLRPKSYIHRTTDWNEFPNGRWGFSFAPSFGALTDYHLFYMKMDASHDA
LLDEWGHSLTSEEDVWKMFACYISGEKNVLGKSVRHFPWKDEEVSLETNLIQSQLVEYNR
KGILTINSQPPVNGKPSSDPIVGWGVPNGYVYQKAYLEFFTSASNIPALRAVLKNFPNIN
YHFVNKSGEVNETNADGEQATALTWGVFPGKEIIQPTVVDPVSFMIWKDEAFSLWMERWG
KLYEPGSPSYSIIDEVSNTYFLVNLVDNDYPQGSCLWKVLDAMLEYQKSTSQDVKS
>A0A1M7THX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfitobacterium chlororespirans DSM 11544|TrEMBL
MENRFKQSLLDPNTLSVTWELVPGRGAREKAQESALLAAEQAAKGGKVHALTITDNPGGN
PAILADYLGQEILKLGIEPLVHFTCKDKNRNQMESQLYALDRAEVRSLLVMTGDYTVSGF
KGRPKPVFDLDPTHALELIAQMNEGLGIPGPKGMSYHQPSDFFAGAAVSPFKGTEAEQMV
QYYKLKKKVASGAQFIVTQLGYDARKIHEVLQFMKLNDLNVPLVGNIYILPFGAARIMNQ
NQLPGCVVTDKLLAEIDKERTAEDKGVSARLLRAAKMYALMKGMGFAGVHIGGHNIKYEQ
VEYVIEKGEELSKDWMALVPEFDYPMPNGFYYYEKDPKTGLNSTTPVNRKNLPLDAPVGV
AYSGMRLMHSMLFTPGKNFFPVMRKIYKGRKDHRKHGLEHLAKVITNDCKDCGDCAMFEL
AYLCPMSQCPKNQRNGACGGSYQGWCEVYPNQKQCIYVRAYARLKKYDEEGDLDSHHIPP
ADWDLYQTSSWSNFFLGRDHSGKILGIPTPEEEAAKVKGAESAK
>A0A8E6N4H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Typhimurium str. CFSAN000648|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1G3DX71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium RIFCSPHIGHO2_12_FULL_40_16|TrEMBL
MSLLAQYFAQQQFCVLVEYLSAHQAQWSVKTEFVGFPAAMTLADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDAKTQGQKNLLLLTGDKLKQHRHSHDLEPRTRYL
ESVNAVMEAKRQGSFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMTAL
QDAHAFLARHQYALKILACVMPLTLARAKFMLKHKVAGIVITPHMLQVLQQEKEQGLSDR
VYVRCALQILMCRHLGFAGVHLSACHQPEEQSLLESYIEEYRHLSFAECERLWNSLWQVQ
TGTEFHPKLTYYSRPATSSQIIKYQHLHLMHDALFESKLAKGMGRFIFNFNVWDRSRAKQ
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTKILQEKLIPTVSIAVRGTSSWKNWYVEAAG
>A0A7C7XY30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MDITDLYAHEGQTDPVISFEFFPPKTDVGYRSLFRTIEELKGLSPGFVSVTMGAGGSTRA
KTVDLTIEITRDLGLETMCHLPCTGFRPHEVGKILDQLAEGGVLNVLALRGDPPRDDPDF
EPPSDGFKFANELVEYIADRGVFSIGAACDPEVHPEAPDAAADLINLKRKVDSGTDFLVS
QLFLDNSKFFSFLEDARGAGIHVPIIPGIMPIATVAGIRRMTAMNRTIIPAELEAELQRV
DGDDAATYELGVRWATMQCRELLDRGAKGIHFYTLNRSPATRDITQSLFS
>A0A8C4UV22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falco tinnunculus|TrEMBL
MSSPRAQEQRANKKTCAPDAHGCHCLLGCSEDKSDVDSFEKLTMVNETQHTCTAGSSSKS
DGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDAGDKWFSLEFFPPRTANAAVN
LISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTK
DDITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDICVA
GYPKGHPEAESYEADLRHLKEKVLAGADFIITQLFFRSETFLKFMKDCQAIGITCPIIPG
IFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMV
HGLHFYTLNREVATTDVLKRLGIWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYI
YRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVF
TCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNINGKPSTD
PIVGWGPSGGYVFQKAYLEFFTSSEIVMALLKVLKKYELRVNYHIVNVKGQNITNAPDLQ
PNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDN
YYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQE
>A0A6L5DZK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinifilum sp. N1E240|TrEMBL
MKVIEHLNQAIENKTTHFSFELLPPLRGNSIYKVFNTIEKLKEFDPKYINITAHRDEVVF
VESGNGGFEKKITRKRPGTVAVAAAIQNKYKLTVVPHVICSGFTPEETENALLDLNFLGI
YDLLLLKGDSSPRHDFIPTEGEHKYALDLIGQVNDINRGQFLDGTHVDPFETPFSFGTAG
YPEKHEEAPNMDSDIYWLKQKVDAGAEYIVTQMFFDNQKYFEFEKRVRDAGITVPVVPGI
KPISALSQLTVLPQIFKTDIPEALAAEVRKCKSNKEVKQVGVEWGIQQSKELIQHGVPSL
HFYTLMASNCVRDIAKAVY
>A0A3M1IIZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MTFPHYDVKSVVEILNENDFSLSAEIIPPRNGTDFHEVFSILEKLKEAGFDFISVTHGAG
GSLRGGTLPISYHAQTHFGLTAIAHLTCRNMTKEDLENVLIDHHYFGVRNILALRGDPPD
GIGAEFHPVEGGFQYAYELIELIQRLNEGKYLPRKNFDEGDFRPGIKTQFCIGAACYPED
PKEVRLKY
>A0A431PLY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobiaceae bacterium|TrEMBL
MTSEATAPAGSQGQKRPAISFEFFPPKTEEMERNLWEVINRLAPLTPNFVSVTYGAGGST
RERTHSTIARILSETKLTPAAHLTCVDATKADIDEVVARYHDVGVRHIVALRGDPVSGIG
NAYTAHPEGYQSSADLVASIKRHHPDMEVSVSAYPEKHPESATLEADIDALKAKVDAGAT
RAITQFFFDNDLYFRYLDRVRAAGITIPIVPGILPVQNFKMASNFAKRAGATMPEWLSAK
FEGLDDDADTRRLVAATVAAGQVQKLAKHGVENFHFYTMNRADLVFAISHLLGIRPNGAQ
KAA
>A0A0H3B7Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pseudotuberculosis serotype O:3 (strain YPIII)|TrEMBL
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIAIDYWNSGIRHIVALRGD
LPPNSGKPEMYACDLVGLLKDVGDFDISVAAYPEIHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFD
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A1H2C0U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes derwentensis|TrEMBL
MSLGLPSRLPGAPTVGDLIRGPAPTFSFEFFPPKTPAGEQALWQAIRELESLRPSFVSIT
YGAGGTTRDTTVAVTERVATETTLLPMAHLTAVDHSVAELRNVIGRLAGAGISNILAVRG
DPPGDPTAEWVRHPDGVLYAEDLVRLIREAGDFCVGVAAFPYKHPRSSDVESDTRNFVAK
CRAGADFAITQMFFDADDYLRLRDRVTAAGCDTPILPGVMPVTRTATIERSVQLSGAPFP
PALLRRFEELAGDDEAVRALGIESCAEMCARLLAEGVPGIHFITLNRSTATREVWQQLTP
TAVTA
>J9FEL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gut metagenome|TrEMBL
MYKTIDTLREFDPKYINITTHRSEYVYKELGNGLFQRNRLRRRPGTVAVAAAIQNKYNIT
VVPHILCSGFSREDTEYVLLDLQFLNITDLLVLRGDKAKHESEFIPEPNGYNHAIELQEQ
INHFNQGIFVDGSEMRITQTPFSYGVACYPEKHEEAPNMETDLYWLKKKMETGAEYAVTQ
LFYDNQKYFKFVERARQAGITIPIIPGIKPFKKLSQITMIPKTFKVDLPEELTHEVLKCK
NDEEARQVGIDWCIKQCKELIASGVPSLHFYSVGAEDSIREVAKEIY
>A0A353NBZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MQKAGTCGCWPVCEAEQGGCSVIRNFNDDISTPEKFVVTLELVPGRESSGRTTDMIKGIS
KDAAQDGRLTAVSITDNPGGNPALSPDMLGYEILDSGMDVIVHFTCRDTNRVGMESRALQ
LARMGMKNILALTGDYSGKGFGGKGTPVFDFDSVVLTSMFKDLNRRLIKTGHSSIFVTGC
AVSPFKYTEAETYVQYRKLERKIEAGASFTITQLGYDVDKYEELLHFKKDKGIDIPVIAS
LYLLDKRSAKPMNAGRVPGVVVTEKLFNKVMQEWEDPVEGRNHAIERTARLGVVLKGIGY
NGIHLGGIHDSFDTVGRILDRMEAIEHNWRDYVEEFREDEPARFYIYKKQESARDAAQKE
KIKMKITDNCHYMFLKTAHDLFFDKGASLAPVYKRISSSLDRNKKSWVLKRFLEDPFKKL
LLSCQSCGDCGIQHVGFLCPESGCPKHTRNGACGGSNNGYCEVNKDTLCVWVRAYERMRK
HGETQKLTGEFVPPRLWELKDTSSWINFHLDRDHQKPKEEPKAKAL
>A0A1N6S7H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus macquariensis|TrEMBL
MKPDLRKAWENNVLIGDGAMGTFLYQMGFPVGISYEELNLTAPEVIKDVHRRYVEVGAQV
LESNTFSANFDKLSKYGLESKVEEINRAGVRIARDAAGPDGYVLGAVGSIRGGKRTNVST
KKLKLYFEQQITALLAEGVDGILLESFYDVEELSIALSRVRKLSDLPVVCQFAIEDVART
LDGYTMTEALHILQQEGADVIGFNCRTGPNGMMRAVESLGNQLSVPVSVFPNAGVADYVD
GEVRYTATPEYFGTMALRFADLGVRIIGGCCGTTPEHIKEISKALTGYVPSPIDKNHVVA
TPVARIVHEHTNDTVEDDREPTIVDLVKQRHTVIVELDPPRDLDINKFMLGAEALKKSGC
DALTLADNSLAVTRMSNMALGYLIQDQTGMRPLIHIACRDRNLIGTQSHLMGFDALGIDH
VLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKANFVVGAAFNP
NVKHLDKAVQRLEKKIAAGADYIMTQPVYDPKLIGAIKEATAHLDTPIFLGIMPLASGRN
AEYLHNEVPGIQLSDEVRARMVGLEGEEGRAMGVTIAKELIDEAMKHFNGIYIMTPFMFY
GMSVELTEYVWKRSGREVTPLFRS
>A0A0P1FRL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobius gelatinovorus|TrEMBL
MTVPAVSFEFFPPQNLEASFRLWDTVQALAPLGPRFVSVTYGAGGTTRDLTRDAVATIHK
HSGLKVAAHLTCVDATRAETLSIADGFAEAGVSDIVALRGDPPKGTGAFQAHEDGFASSV
ELIEALAAKDKFTIRVGAYPEKHPESADHQADIEWLKRKFDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIIPGILPIENFKGTRNFAKRCGTLVPDWVTDAFEKAERDGRHDLLAT
ALCTELCSDLIEGGVDSLHFYTLNRPELTRDVCHALGVTPQARLENVA
>A0A518GY65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tautonia plasticadhaerens|TrEMBL
MHILDILDRDRTTFSFEFFPPKTAQASEDLFMTISQLQELQPSFVSVTYGAGGTTRDRTH
ELILRIQGETNLTAVSHLTSVCHTREELSAILDRYAASGVENILALRGDPPRDLDGYDRA
NDAFQYAEELVRFIASHPRSPHARGFGIGVAGFPEGHPNTPNRLNELDHLKAKVDAGAQY
ICTQLFFDNRDFYDFRERCELAGIAVPIIAGIMPVTSKTGMVRMADLALGARFPARLIKA
IDRCAPDFTAEQVAKVGIHWATEQCRDLLDNHVRGIHFYTLNKSDATRRVFENLGVKDSV
ALRTA
>A0A3N5EIN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKSGSNLEKVLAAGHFAVTAECGPPRGADPEVVRRKAAYVKGNIDACNVTDNQTSVVRMS
SIAGCMILKEMGIEPLLQMVVRDRNRIALQADLLGASALGVRNLLCLSGDHQKFGDDPQA
KNVFDIDSMQLIHLTRTMRDDGVFPSGQKLDGAPKFFIGCAVNPFADPFEIRVPRLKMKI
NAGADFVQTQCIYNMEKFKVYLEDAMRQGLHEKVKILAGVTPLKSAGMAKFMKKMVAGMD
IPDAVIKRIADEPKEKQAAKGIEMCIELIHELKEMEGIAGVHVMAIEWEEKLNEIIGGAG
LLPRPVVE
>A0A1D8YBQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. LM091|TrEMBL
MTAISFEFYPPKTDDQRAQLDRTAAKLKAFAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASELISFI
RAEHGDAFRIEVGAYPETHPQASDALLDLKHFKTKIDAGADAAITQYFFNADAYFHFVDA
VRALGVTVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAESVRAFGAEVV
ASLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLRS
>A0A417W9G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OF10-22XD|TrEMBL
MKIRDIIGQEKATLSFEVFPPKKDTDFASVEAAALGIAALRPSYMSVTYGAGGSTKGHTI
KLANEIQEKYGVPTIAHLTCVCANKDSIRTALSEMKNAGIENILALRGDIPKNYDGQVFT
DFAHASELVKLIKESGDFCVGGACYPEVHPDSANKQDDIANLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRIREAGIAVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEVAAGIQANLSDILLA
>A0A0F6U2I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa NIES-2549|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILHQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFDCLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A2A6F616|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sanjuanii|TrEMBL
MHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAKIFDGWVDAINAV
DASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAAMGVANMLCLTGD
GVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFLGAAINPFAPPID
FRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILCGVGPLASAKTAK
WIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSGVHVMAYRQEEYV
AEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHDDITETQVDMVKTAH
>A0A522WQQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum sp|TrEMBL
MSLPLSELPIAAAIRRPVSVSFEFFPPKTDKMQASLWECIQRLEPLAPQFVSVTYGAGGT
TRERTHETVVRIARETRLKPAAHLTCVGHAKGEVDDIARLYWDEGIRHIVALRGDMPDGQ
PYAAHPEGYAYAVDLVAGLKRVADFEISVAAYPEMHPDAPDAGFDLDNLKRKLDAGATRA
VSQFFFDPAVFLRFQERCAKAGITAPVIPGILPVTNFAQVRKFSAACGASVPDWMAHLFE
GLDDDPETRRLVAATLAAEQCRMLAANGVEQFHVYTLNRADLAYAISHILGVRPKTAASA
EVAPTSRTPS
>A0A7Y0H246|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp|TrEMBL
MELNNDPLGTVSVHPVRGLAVTATPEASVGARAQAVRSRWSTPAPIDRPTVSFELFPPRN
PDAAPKLWATIEALSAARPDFVSVTYGASGKTRDTTRGLVRRLLRETSLNPIAHLTCVGT
SRDEVTAVVEEFLDEGVRSFLALRGDPPVDDPDWHPHPQGLSTAAELVELLREIEARRCS
TSPAQQVRATVRPLSIAVAAFPRGNAGTGSTRAQDVAALLAKQHAGADFAITQVFYEASA
YLELVAEARRAGVTIPIIPGIIPATDPARLLRVEGLTGVPVPRDLLALLGSVDDDVERHR
VGIRASVDLVNGVLDGGAPGVHIYTFNTHHAALDLLEGAHLGGGGPTAPDQASEPQVTAP
QTDHSPRG
>A0A671KP33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus anshuiensis|TrEMBL
FASTFSGSNLPNGLPKSRGVSNSGESSKESSRCSTPVLDTDRLQDKMKRRIESGDHWFSL
EFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVNYCGL
ESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLVKHI
RCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDSGAHFIVTQLFFRAETFLKFVKD
CRAVGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRSYGIQQA
VEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKVEDV
RPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWG
EELMNEESVYEVFTNYITAQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGVLTI
NSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVN
VQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDE
SPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFALLDSPRETQEGSQS
>A0A2N5GAY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. V3-13|TrEMBL
MSFLKKMENQILIADGAMGTLLYSYGTDCCFEELNLSEPEQILNIHKAYINAGADLIQTN
TYAANYLKLQRYGLEDSVKEINSAAVKIARNAAQDNAYVLGTIGGNRGIKPHSISIEEIK
RSFREQLYCLLLAGVDGLLLETYYDLKELETVLAIARKETALPIIAQVSLQETGILQDRT
PIDEAFAKLEQTGADIIGLNCRLGPHHMLLTLEQVPLPKHAYLSAYPNASLPAYVDGKFH
YEGDAEYFRKSAQPFREQGVRLLGGCCGTTPEHIRAFAAELKDKAPVTNKIVKLKDKKII
VETATVKRAEPPLDQVVKQRRSVIVELDPPRKLNTGKFFEGAKALQDAGIDAITLADNSL
ATPRIANEALGHLVKSKLGLRPLIHITCRDRNIIGLQSHLMGLHTLGLHDVLAVTGDPAR
VGDFPGASSVYDMSSFELIQMIKQLNEGLSISGKELGQKTTFSVGGAFNPHVRSLDKAVK
RLEKKIDCGADYFISQPVFSEEKMIEIHEATTHIEAPIYIGVMPLISSKNAEYLHNEVPG
IKISESIRERMARFKDDPAEACREGLEISKSLIDAALDLFNGIYLITPFLRYELTVELTN
YARRYDNVLTGGNHHDQTKIL
>A0A8F6C730|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella sp. HaHa_3_26|TrEMBL
MKVTDHIKNANGKTLFSFEIIPPRKGNSIQQLYNNIDPLMEFKPPFIDVTTSREEYLYIE
KQGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGLNNV
MALRGDAMKHQQYFEACDGGHQFAKGLVSQIQNLNNGHYLHDVLEADDKSDFCIGVAGYP
EKHLESPSLKTDLKRLKEKVDAGADYVVTQMFFDNNKYFEFVKAAKAEGINVPIIPGIKP
LAVKRHLQLLPQVFKIDLPEDLIDAVDGCKSNEQVRQVGVEWAIQQSKELQQAGVPVLHY
YSMGKSDNVKAIASELF
>A0A6V7VPZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meloidogyne enterolobii|TrEMBL
MNKIQYNNSLLNKLNFINSTDGPFFCIEVSPPKEINKINNFISSINKLINNTTTNNSFLF
LSIVAHAENNPTNFSLPNSSTSIASKILNEDILPKNSHLILHITGKSFINFPHSFVDFYF
TKLKQLGINNYFVLSGDLPKRENYNYLNYNLEISPKSPQLDSLHLIKRIKSNKLSTNNNN
NLLTFAVAGYPECHPFAYNRNSDILFLKRKIFEGNANFVICQFSFDRGAEKFFQFVADCR
QAGINVHFIPGILLFQSFSSLLKFSSLTKIKIPQEMFNLLSSHRYNDNLIKYYSLWLAYN
ICQKLLTKSLLNNIRAIHLFNSNQWEMTRYL
>A0A7U4SDW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzicola|TrEMBL
MISIDMPSHTRAITDAYSLEVSVKDIGALTKAAPRLLPGSSMFIPYLPGQHDAARLAAAQ
LVRSLGFEPMPHLSARRIGAPEELQAFVARLVDEAGVTRCFVIAGDPSTPKGPFADSLSL
IETGVFERSGIRTIGVAGHPEGHPIMRTAEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
MVVTWVEALRARGIPHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLASRLTDAHGDIRLHVFPFGGIAQSVAWVAQYRSRASSQDRMSSVRADQA
>Q4T956|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetraodon nigroviridis|TrEMBL
MVNQVQSVDSGWQSSKTDSSGASNSSGESSKESSRCSTPGLDGDHSNRLRDKMRRRIESG
DCWFSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKDKITGYLGKAKRLGLKNIMALRGDPVGADWEEEEDGFNYAI
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEQDLRHLKEKVDAGADFVITQLFFRAETF
LKFLEDCRRVGITCPVLPGIFPIQGYQSLRQLVKLSKLELPEEITSIIEPIKDNDAAIRN
YGIQLAVQMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWSSRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELLSEESVFEVFTCYITAQTNRSGQKVLCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWA
KLYEDESPSRMIIQYIHGQRLSSGQLSVAGPGRHAGPAGRSGGGAGPGGGPAPGCVRVGW
REAAPGGRSSLQAVVQPCDSTDEEGPKSPGPQDAHTGAGGPWLLGGEEPAAEPAPKAPPP
GRRPHSGLRTGPLGSAPPRAPLLRFWFCLRAKPRLGCRSSTPATPSWAAESWDCPTPCPT
QASFSSSQELWVRRQVRRPWQSPAHVHHTPVSFRYSGLRAAWPQSLRTPGEDFSCCGHNF
AQHRR
>A0A5N8XRD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces spongiae|TrEMBL
MALGTASTRTDRATTVRDMLVDGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVKATEQIASDTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDADVRHFVD
KCRAGADYAITQMFFHAESYLRLRDRVAVAGCTTPVIPEVMPVTSVKMLERLPQLSNASF
PPALKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPQV
>A0A1L7VG18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium proliferatum (strain ET1)|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAMYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A1H3WE72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiothrix caldifontis|TrEMBL
MTDDHQHDHVNHDDLIFSFEFFPPKTDKGAENLRAVRTQLAALKPRFFSVTYGAGGSTQA
NTLNTVLEIQRDSGIEAAPHLSCVGSSAEQIREILDTYRNNGIKHIVALRGDLPSGSRDL
GQFRYANELVEFIRKETGDHFNIEVAAYPEMHPQAPNLKVDIDNFVRKVNAGANSAITQY
FFNADAYWHFVDECVKKGVEIPIVPGIMPITNYSQLARFSDMCGAEIPRWLRKQLETYAD
DVEAITQFGEEFISLLCENLLETGAPGLHFYTMNRVEPTMSIWKNIGLAD
>A0A2K8LQR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. AA4|TrEMBL
MTSVIERLRGDGPAFSVEFFPPRDEADEAVLWKAIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLCPMAHLTAVDHSVSELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPEGLTYAAELVALVRSLGDFCVGVSAFPYGHPRSADLESDTKHLVRKFRAGADFAIAQ
LFFEAEDFLRLRDRVAAAGCDALVLPGIMPLTTLRTLHTTIKLSGAPASQRLLDRLEPFS
DDPKAFRAAGLDWVTELCEKLIAEGVPDLHFYTFNRSKATREVVTRLGLVPARTY
>A0A2S7TV67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnobacter sp. SAORIC-690|TrEMBL
MMNISFEFFPAKTDEGAEKLRATREKLSERKPEFFSVTFGAGGTTQDGTLSTVLEIKAAG
EEAAPHLSCVGSSKEKVAALLKQYKEHGIKRIVALRGDLPSGMLETGSFRYASELVEFIR
QETGDHFFIEVAAYPETHPQAKSPAADVDAFVHKVNCGANSAITQYFFNLDAFLYFRDQV
QHRISIPLIPGIMPVTNFSQLARFSDACGAEIPRWMRNRLQHFGDDRESIRAFGLEVVSN
LCEQLIREGAPGLHFYTMNNAQPTLSILDQIGY
>A0A4R3N8L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomonas haemolytica|TrEMBL
MLPISFEFYPPKTDEQREQFDRSVRKLKAYAPEFMSVTFGAGGSTLGQTPETVQRLRQQH
ALDGVPHLTCVGGSREEILALLARYRALGCTRIVALRGDLPSGMARSGDLRHASELVQLI
REEHGEHFHIEVAAYPEVHPQAPDAQVDLRHFKAKVEAGASGAITQYFYNADAYFRFVED
AKRAGVDIPIVPGIMPIANYAQLRRFSEACGAEIPRWIDRRMRAFGDDGAAIREFAADVV
AALCRRLLDGGAPGLHFYTLNLARPVQAVLQRLE
>A0A5C2EXL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzicola|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPGYVSCTFGAGGSTLNYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVKVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
AALCERLMAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A7V1AKW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MNFKEALNSGKFAVTAEVGPPKGTDIKEMLHDAEALKGKLDAVNVTDNQSAVMRINSLSI
CKILLDMGHEPILQMTCRDRNRIGLQSDLLGASVLGIRNVLCMTGDHPNAGDHKEAKSVY
DIESVQLLRVVDSLNNGKDMMGNDMKGATDFFQGAVVTPEADPVEPQLMKFEKKVAAGAN
FFQTQAIYDIGKFKEFMTYAKKFPVKILAGLVLLKSAGMANYMNKFVPGIKVPGDLIDEL
KAAGKGNALDTGINIAARHIRQLKEEEICDGVHIMAIGAEDKVPLIMERAGLL
>A0A8J3BA20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditerricola satsumensis|TrEMBL
MAYHVHRLREKLRLGKFVITAEVEPPKGADPTPTLEKASLLRHVVDALNVADCPMANLRM
SPIALAHILQDDLGIEAIFHLTCRDRNVLGLQAELLGAAALGVRNILTLTGDAPERGDHP
TATGVFDVDAVGLIRLAATLNAGRDVNGNRLEAPPEFFIGAAANPGAEDLAREVRRLEEK
VAAGAAFIQTQPIYDVETAERFLEATQHLDVPILFGLMPLKSYKMACYLNEKVPGITIRA
DVLRRVERGGAGGRGGRGARAV
>A0A662RUG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon|TrEMBL
MKKMAEEVYSDLMREIQSGRFVWTGELEPAKDIGEAIEAASELKGLVTACNVTDNPQSFA
AINSLAAAYKIQQETGMECIYQLRCADRNRLALFSDVMAAGVLGLKNILALTGDYVSLGD
TPRAKPVYDLDSTTLTRMIHTLVHEGKDISRTEIPNPPKLHVGTAAGPGVDPLEPELYKM
KRKALAGAEFFQTQVVYLPEVLDQFFKGVKELNIETPILVGIFPAKSYGAAKFFDEYVTG
VDVPPDFLKELEATKQIKDKEKRKEEVDRVNVEYFTGFLEHLKDTPAVGCHIMAVGYPRI
IPELKKVME
>A0A2N5BBK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FFUP_PS_41|TrEMBL
MSLLKTALREKTFVCVMEFVPKPSTERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEDEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMNRQAAPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPMWATRLGAQVLHKVEHAVKHPLVGCETCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTALLTERLIPCIELETRHRSSWPQWFQAQTP
RQLSPQPAPRTQPES
>A0A7C4MQT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MRDKNDGILHYVPGFVLCIVLGWMALQWDQSIHKWQKNFQESEKILKASQGDGGVFPSYT
QYREEKEKKYQEELSAFERGDMKEKPKKPYLLLEKDYAFIAATKEIPFKFRFGERMIQFQ
LTYVAVLLLGGMLIRNVIGLPKIFQPGAVIARPVIKPGIILLGGYYLWSNLLKVGIFALL
LVLVFILGTTILVSVLGKRLKQDDGLMGVMAAGTGICGVSAAVAVAPVVNAKPRDFFYAV
GTILLFGTVALFTFPYIGKALGMTEPVFGAWVGTAILNTAQLVAAATWYGHDSLLTANII
NIVRVGFIPFVVIFCIWFYVIKQATSGDEKGKIHTWQVIKEKFPLFILGFFTMVTLNEFG
VFTEDHRTIFGKQFLQIFFAIGFAGVGLNIAFEDLKKAGIVLWEMGVAVVGGCCGTTPDH
IRALAQAIGGRPVAPRRAPAVTARKSAPGAAAGPRAGNPVRELMKSDRFLVSVEIRADRR
SALEGIIAGASSIAAAGADLFDVPDNPAATVGRDAMVVAARLQSALGRPAFPHKSVVQAN
LLQLHSSLIGCWDLGLRAVLAVTGDPPSLGHLAGMARLVTDIKSSVELLRLIRELRNGRM
INGEEIGDPPDLCAGCAVGQPTPQQLSWLKKKVEAGAEFAFSQPIFDVDTFLRLKDGTDG
LGLRVFPGLMPLTSRRGAESLASGRVPGVRVPEQVVEQFRRYDAPADQRKLGLDLARDLA
ARMIEDGASGIYLIMPFGRGCYEETASLVSHIRKVASSKTASPR
>A0A6J4RS79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Rubrobacteraceae bacterium|TrEMBL
MQDRRSGLVEALRRPRYEVIPLPGVEDAVAEHVPKNVKLTVTASPKKGLGPTLELAERLS
GEGFEVAPHLSARLIRDRAQLGEILARLREADVRDVFVVAGDAPEPAGEFEGSAALLGAM
DEIGHGLEEVGITGYPESHPLISDEDTIQAMFRKEPHATYITSQICFDTDTINDWVLRVR
RRGVGLPIYVGMPGAVGMAKLVRISSNIGLGESARFLQKYGNWFWRMFMPGGYSPDALVE
GMSASLGDPHRKVHGFHIYTFNEVEKTEAWRLGALERAGATPQERHKEPTA
>A0A521RSA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reyranella sp|TrEMBL
MSPDTGPIGNPLSSTGSTTATEFPARAPQRLAVSFEFSPPRTDAAEQTLWETVKRLTPLH
PSFFSVTYGAGGSTRQRTHDTVARLKNETGIDAAAHLTCVAATQGEIDDIARAYWDAGIR
HIVALRGDPPGGMGGQYTPHPGGYANAAALVTGLKKIGNFQISVAGYPEKHPASADEKAD
LENLKAKVDAGADRCITQFFFEAEDFLRFRDRAAAMGINVPIVPGIMPVSNFQAVNRIAG
LCGSKVPSWFASMFDGLDDDLETRRMIAATVAGDLCRRLRDEGVEQFHFYTLNRADLTFA
ICHLLGVRPQ
>F6EPJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoyosella subflava (strain DSM 45089 / JCM 17490 / NBRC 109087 / DQS3-9A1)|TrEMBL
MTRQQARTEVLVSLLTRVRYEVLPTEKVLDEVYATLPPGATVTVTASPAKGQQATLHIAE
RLAALGFDVVPHLAARMISGPGELAEITSRLQSARITKVFVPAGDDDTQGRAYSSALELL
EDLSNMGNPFSEVGITGYPESHPHIHDDLTIQAMWDKRQHATQIVSNLTFDPGVLSDWVT
RVRARNVNLPIFVGLPGPVERTKLLRMAAKIGVGESARFLAKNGGLFARIATPGGYDPAR
FLGRAATALGRNGMNIAGLHLFTFNQVAETEAWRTAQLARLLGHRKSYGHIQATELPLAG
TP
>A0A0N8PSX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kouleothrix aurantiaca|TrEMBL
MPANSDFQRRLDAGQLVVTGELAPPKGASRATLERLAVAMRDHVDALNLTDNQRGIGRMS
ALGAGIVVQQLGIETIVQMTCQHRNRIALQADVLSGSVCGINNFLCMTGDHPKIGDHPET
KNVLDLNSFQLIRALRTMRDDATFQSGTPLSDAPRFFVGGVANPNIERIARLEKKVQSGA
EFIQTQIIFDIERFRQWMADARALGLHKHIHIMAGVMVIRSAQSAHFLRDHLPGSRVPDW
VVERMAAAPDAEREGVQIAAELTQEMLAIEGVRGVHIMSVGWTKAIPLVVEAAGLLPRPP
APPAE
>B7J554|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455)|TrEMBL
MAHSVEFFPPKNAAGEERLREAITALLPLGPEYASVTFGAGGSTRERTFATVTMIGQDYG
LEAVPHLSCIGSTEAGIREILEDYRKQGIRRIVALRGDLPEGMENPGHFQHAADLVAFIR
HFGGFEVYVAGYPDIHPRATSARDDVMHLAAKVRAGADAIITQYFFNPDAYLQLRDELRR
EGIEVPLVVGVMPITNFEQISRFSAMCGADIPQYLRRRMDAYAADPQSQYQLGIELLSRQ
CQLLLREGAPSLHFYTLNQAEATAAIWRNLGF
>A0A5N8YC21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium AC-647-N09_OGT_505m|TrEMBL
MSRLSEVLESDQFAVTAEINPPKGVDIQDTLSKAKALRGFVDAVNLTDQQSAVMSMSPLA
LASLLMQLGPEVTIQVTCRDRNRIAIQGDLLGASALGMENILCMTGDPVGTGDHPDAKAV
FDMDSIGLLRTASALMKGKDMGDNDLKGSPSFYLGAVVNPAASELADEIIRMEDKVEAGA
RFFQTQAIFDPTELEEFMSMVKPLGVPVLAGLIVLKSGDMARSLNLRLPGVHVPDTIIEE
LDTAEDKAQKGIEIAGRTIRDVKGFCNGVHIMAIGWERRIPQVLEAAGILAREGALGT
>A0A1M6GH93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geosporobacter subterraneus DSM 17957|TrEMBL
MSLLKETLDRGGFAVTAEMAPPKGTDFAHLLECAKAIKGRVHGVNVTDFQSAVMRATSLV
TCKLLKDEGLEPVLQITGRDRNRIAIQGELLSASVFGIKNVLSLTGDHTVVGDHPQAKPV
YDLDCIGILQAATILAGGKDMVGNELKGTPEFYLGASVTPRFDPLDVQIFKMEKKVKAGA
RFFQTQAVYDLETMRVFREKTKGMDAKVLAGIIPLKSVGMARFMNNNVPGIHVPEDVIAR
IKAAEDKVKEGIQIAGEFIRQLREENLCDGVHIMAIGAEENVPAILDAAGL
>A0A1J5B320|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium CG2_30_32_10|TrEMBL
MKVIDIINNSKKTLFSFELLPPLKGNSIVPIYKAIDPLMQFSPSHINITYHQEEVVYKKL
KNGLLEKKTVRKRPGTVAISAAIKYKYPNVEVVPHIICGGFTKEETEYALIDFHFLGIDN
ILVLRGDPPKTSRTFITEKNGHSHASELISQIIDMNQGKYLDNELENSTSTDFCIGVAGY
PEKHIEAPNLKSDLRYLKEKINNGAEYIVTQMFFDNQKYFDFVKLCREEGINVPIIPGIK
PITTLNDIKLLPQIFNIDIPEDLEKEIKKCSSNEQAFQVGIEWGIKQSKELVKFGVPALH
YFTIGISENIKKIAETIF
>A0A5M8H8J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces parvus|TrEMBL
MALGTASTRTDHARTVREMLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLERFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A1E7GHW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium S5133MH15|TrEMBL
MKTESNLEKVLAAGHLAVTSECGPPRGAVAKELTDKAKYLEGVVDAVNVTDNQTAMVRMS
SLAGSVLIKQQGMHPLLQVVTRDRNRLAIQADILGAYSLGIDTMLCLSGDHTKFGDHPMA
ANVHDIDSIQLIQMVKGMRDESKFQGGSDIKGAPKMFIGAAANPFADPFELRVMRLAKKI
AAGVDFIQTQCIFNIEKFELWMEGVRKMGLHKKCYILAGVTPMKSVGAARYMKNRVPGMD
VPADVVERMASVPKEKQPDEGVDICIETIERLKKVEGVAGFHIMAIEWEEKVE
>A0A416JZT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium AM48-27BH|TrEMBL
MKIRDMIGQGKPTLSFEVFPPKTEANYESVEKAALEIGKLHPSFMSVTYGAGGGTSKYTV
SIADKIQRECGVPTLAHLTCVSSTREHVHKVVEELKEYNIENIMALRGDIPKDGNIQNDY
RYASELIREIRESGDFCIGAACYPEGHVESVNKTEDIQHLKEKVEAGCDFITTQMFFDNN
TLYNFLYRIREKDIKVPVVAGIMPITNAAQVARSIQMSGCYIPARFKALVDRFGDNPAAM
KQAGIAYATDQIIDLIANGVNAIHVYSMNKPDVAAQIQANLSEIL
>A0A451DAT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MINMIQDHNEKYNYESYHLKNKIKISFEVFPPKDVFLEKKLFHNIKLLNKCHPDFFSVTN
SINSENRDSTFFIVKKIHSLTRKTVFAHFTTVGYDELDIQTIATNYWKNGIKHILALRGD
LPAQYTKKIIYANNLIKLLKSINDFEILVAAYPELHPESSNLQEDLNNLKNKIDLGVKKA
VTQFFFNIDKFLKFRDNCTDMGLSVSLIPGILPILNINQLKKFSNMTNVDIPQWIFNDFY
KYEGDFDKCTSLSVSIAVNLIIRLYKEGIKNFHFYTLNQSYLSLKICHQLGLI
>A0A2W6ESR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MALGSASTLPRTVAISDLLAAGGRSVSFEFFPPKTDEGERLLWQTLRDLERLQPTFVSVT
YGAGGGTRDRTVGITERIATETTLTPVAHLTAVNHSVAELRRIIGLYASVGVRNVLALRG
DPPGDPQADWQAHPEGLAYAEDLVRLIRTSGDFCVGVAAFPEKHPRSPDIDTDIRYFVQK
CRAGADYAITQMFFRAGDYLRLRDRVAAAGCDIAILPGIMPVTNVKQIERFAVLSGAAFP
ADLAERLHAVEENPEAVRAIGVEVATELCGTLLAEGAPGLHFITLNRSTATREVWARLAL
SERTLPAND
>A0A6J0XR77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odocoileus virginianus texanus|TrEMBL
MDRPKPKVFPVGHCCPSLGMRASEAGSRRFSVPPSISRNSAMVNEPRGNGGPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEAESFEADLKHLKEKVAAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGAELTSEESVFQVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKPWPPPSDTMMAARLV
>A0A6J0XKW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odocoileus virginianus texanus|TrEMBL
MDRPKPKVFPVGHCCPSLGMRASEAGSRRFSVPPSISRNSAMVNEPRGNGGPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEAESFEADLKHLKEKVAAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGAELTSEESVFQVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLSRPPQDERETEAP
>A0A7K3NAC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda sp. TY007|TrEMBL
MKITDHIKKANGKTLFSFEIVPPVKGKSIQELYKNIDPLMEFKPPFIDVTTSREEYIYKE
KDGLLDKKLTRTRPGTLGICASLKHKYNVDTVPHVLCGGFTKEETEYLLVDCQYLEIENV
MALRGDARKEEKYFTPTEGGHQYATELVKQIQDINEGKYLHDTIESSDLNSFCIGVAGYP
EKHMEAPSLQSDLKRLKEKVDLGADYVVTQMFFDNQKFFAFVKAAREMGIDVPIIPGIKP
IAVKRHLQLLPHVFSIDLPQDLIDAVEACNNNKEVRQVGVEWAIQQSKELREAGVPVLHY
YSMGKSDNVKAIAKELF
>A0A2D6V6R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MLIYRHAYIAQYKRGGWKMIRKITDILKEKDRTYSFEFFPPKTPKGREKLTEVASAFVDL
EPDWFSVTYGAGGSTREATMDIVCDFQKRFEVPTMHHFTCVGHSKAELETMINKMKENNI
CNILALKGDIPQSEDGWKSAADALEYCYQLIELIRAHDSFFSIGVAGFPEGHIDCPDQEM
DSKYLKIKIDAGGEFVMTQLFFDNKDYFEYVARMRKIGVKVRIIPGILPIINYQKLLKFC
ATCGANIPQRVHDIFKPLDGDEEEATYSAGVKFAVEQCSELLEGGAPGLHFYTLNKLDPT
REILDKIKC
>A0A2N3JLH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. BGI2013|TrEMBL
MKADLRKVMQERVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQISALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GEFRYGATPEYFGQTAVQFAELGARIIGGCCGTTPDHITAMKEALADYVPSPILEPDPSE
SKPRIVLHENVDERSGRGGQPTIVDLVKHRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALSINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLEKAVQRLEKKITSGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A533UBQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MDVKVIYEMNPPKVLYNNYFDHDTINKNIDLFMSRAKKISEFVDGIHLTDNVLGVPRVSS
LMLVSMLKRLGISKPISCTCRLYDKNLISIFQFVSEAIFCGVYSILILRGDEPIIGNKIF
DIPPTKIVRILSSHSFNNYIKFDLSVPSKISDTAKIKNKLEARPRAFVTQSISSIHNLQE
IIKMSAPYGIDVIPCIMCPSKRNEISAQKIGLDWRSYRDEPENFVREAATLTEKILLCSP
NSFEDGLDLVMKLKEN
>A0A2E8Q287|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
LKEEAGKRPVFSFEFFPPKKPEGEQTLMNTIQRLKSLDPDFVSVTYGAGGSTREKTRQWV
RDIQDKHDITAMAHYTCVGHGKDEILSNLKDLYSDGIRNIMALRGDPPKGEKNFTPPEDG
FAYGSELIEYIKSTGMDFSLGGGGYPETHQEAASPEQDLQNLKKKVDAGAEFIVTQLFFR
NDHYFRYVKQCREVGITVPIIPGIMPITSFGQIQKFTEMAGCEIPNELTEDIKACGEDRG
RLLEVSLGYSIRQCRDLLKGGAPGIHFYTLNQSQATSTILKAIN
>A0A1H2VEB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas communis|TrEMBL
MKSQKAFSPTFSFELFPPQTPEGVEKLRAARHQLSQFKPKFFSVTFGAGGSTRDRTFDTV
SEMLAEGHPVAPHLSCIGSTRENIYSILRKYQESGIRHIVALRGDLPSGMAQPGEFRYAN
ELVTFIRKEFGNTFEMDVAAYPEYHPQSRSAQEDFRNFRNKIEAGADSAITQFFYNADAY
FHFVDMCETVNLNVPIVPGIMPINKFSQLVRFADNCGAEIPRWIRKKLEGYGDDIASIHA
FGLDVVTDLCERLLKAGAPGLHFYTLNSAVLTTKIWQRLGL
>K6VU41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia rhizosphera NBRC 16068|TrEMBL
MISSATPAPTIVDRLSAPHHGPVPFSVEFFPPKDAEAEARLWRAVRTFERLGPAFVSMTY
GAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSVDELRALVGAYADQGITNLLALRGD
PPGNPLGEWIKHPDGVEYAEDLVRLIRELGDFHVGVASFPEGHHRAPDLEHDTRALVNKL
RAGAEYSITQMFFDVEHYLRLRDRLVAADPEQGAKPLIPGLMPITSLATVRRMAELSGSV
IPDDVQQRFAVAAGDGPQENREAVRAVGIDFATEMAQRLVAEGVPCLHFCSLNFAKATSE
VLERLGVDVRSAMPAATATPAS
>A0A4P6ESB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus protaetiae|TrEMBL
MLRESILNKKTGIITYGMTPPKASYNAEKIAEIAQKQVERLRGLDIDAIILYDVQEESDR
MDEERPFPYMAMLDPEHYSEQYLHELGIPKIIYRCVGKYSEAELADWLKKDNGKDRFSVF
VGASSRQQQRSLELADAYKLSRRHNSGLTFGGVMIPERHMKKNDEHMRVVAKMNQGCSFF
VSQATYNIEASKNFLSDYYHYCNEQEIEMVPILFNLAPCGSVKTLEFMKWLGISIPRWLE
NDLKYSADVLDKSMQLTNKIFEELMEYGLEKGIPVGCSIESVSTRKVEIEASIQMVNDIK
ALIENKLLVETAR
>A0A2N2FTT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-4|TrEMBL
MPRLCVELVPRDSLALERELEIIHELCPAVQTINIPDLLQFPLRSWEGCALAQRWFPATI
PHLRAIDFDLEKPLAIAETLRQHKISEVLVISGDKPLDMSRRSYRTTSCELIRALKKALP
ALKVYAGIDPYRSAIREELDYVRLKCEAGADGFFTQPFFDLRYMEIYYDLLAGLDLYWGV
CPVLSEKSRDYWENRNQAFFPPDFRHELTWNRDFARKSLDFSARTGANLYFMPIRANLQA
YLGDLLR
>A0A1I5MC13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenimonas thermophila|TrEMBL
MFEQFIEKLQDPKKSYITLETTPKHDANFIPVIDTIEKLGIADKVDGFSTTDNPLAKLKF
NSIIAAMLLQQRFKKPVLATMSMRDRNKIALQSDLLGANNIDVRTILALTGDPAKISDQP
AAKGVFESDSTMLLDIIKCFNAGIDFAGREFNIKPRPIYPFAVSNAFAKNPKTLLKKFTK
KLEHGAIGIITQPVFDKENAQMLLELFEEAKHLSNANKGTLIIGLFPITRLKTAQFLASH
VPGIHVPKRWLDILYTANQKGESEEEKRGLELSQKIYEEIKELHPKIHLMTANRFKLAKQ
LLDE
>A0A1W9PXX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfococcus sp. 4484_241|TrEMBL
MSEKTPSKLEKILRQGHLAVTSECGPPRGSDPEVIREKAEMIKDYVDAINITDNQTAMTR
MCSLASCIHLKLMGLEPVLQMVTRDRNRIAMQSDILGAASFDIYNILCLSGDHQSFGDCP
TGQNVHDIDSMQLIQTVRLMRDEGKFLGGDEIARPPRMFVGAAANPFADPFEIRVPRLAK
KVAAGVEFIQTQCIYNLDRFEEWMKRIRDRGLHEKVFILAGLTPMKSAGMARYMKNRVPG
MDVPDEIVKRLSDTPKEKQAEEGIKICIESIQRLKEVEGVSGFHIMAIEWEEKVPEIVRQ
AGLYPRPSL
>A0A242B4H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus sp. 7E2_DIV0204|TrEMBL
MRTDTLFKEKTVFSYEIFPPRRTAPIDTIYHTLDRLKGQQPDFISVTLGAGGTAANLSTA
DIAQKIQDEQFLPSVAHLPAVNFSKDEIVVILEELKQKKVENILALRGDLLPDREPKKDF
CYANDLVSFIQEQGAFNIIGACYPETHGDSENSVTDIRNLKRKVDAGTNQLITQLFFDNN
YFYTFKEKCDIAAIEVPIQAGIMPVVNKKQIERMVKMSNVTLPTKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVAQGADGIHLYTMNNPYVAQKIREATRSLFDA
>N9DE26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter ursingii ANC 3649|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKIVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTAVAPHLSCIGDDKSRIAKLLDLYQSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAETFDADIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERLEKEGITIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A229T5G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. KNN50.9b|TrEMBL
MTSVIERLRGESPAFSIEFFPPRDAADEAVLWRSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGEWV
PHPQGLSYAEELVALVRSLGDFCVGVSAFPYGHPRSLDLDTDTKYLVRKFRAGADFGIAQ
LFFEAEDFLRLRDRVAAAGCDALLIPGVMPLTTPRTLHTTIRLSGAPAPRRLLDRLEPLA
GDPKAFRAEGLDVVTELCERLIAEGVPDLHFYTFNRSKATREVVRRLGLVPARA
>A0A564IC52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella huaxiensis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRAIAQDYWDSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1Q5JDP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02460|TrEMBL
MGPVMDRPTFSFEFFPPRTAQGERTLWQAIRRLEPLRPDFVSVTYGAGGSSRDRTIEVTK
RLVTETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPKGEWTAHPDG
FHHAYQLVELVRSLGDFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFDV
EDYLRLRDRVAAAGCTTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAQHRPDI
AYEIGVAHATLMADRLLAEGAPGLHYITLNKSTATLDIHRNVMSTRSLHAS
>A0A4U2Z576|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas crateris|TrEMBL
MFDELINKLKNDTYITLETTPGHSPIFSPIIETIAELGLDKLVDAFTTTDNPLAKLKYNS
LFAAKMLQERFNKPVIATMSMRDRNKIALQSDLLGANEVDVRAILALTGDPASISDQPHT
KGVFEADSTLLLEIISCFNSGIDYAGKPLLHKSKEIYPFAVVNSYAKNPKTLQKKMQKKI
KHGALGIITQPAYDIQSAKLLLELKDAANEACCNENRSAELILGIFPITKLRTAQFLSAH
VPGINVPASWIEALRDAHEKGADEEYRVGFELSKNLFLELKALHPKIHLMTANQFGLAKN
ILA
>A0A4R6DVI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azoarcus indigens|TrEMBL
MHKTELSIEFFPPQTAEGAEKLRAVRARLAELKPAFFSVTYGAGGSTRERTFATVKEIAA
GGAEAAPHLSCIGSTREGIREILQEYADAGIRRIVALRGDLPSGVGDPGEFRYANELVEF
IRAETGDRFHLEVAAYPEWHPQARTPADDLAAFKRKADAGADSAITQYFYNLDAYLHFVD
AVRAQGVSIPIIPGIMPIASFSKLARFSDACGAEIPRWMRKKFESFGDDAESIRAFGLDV
VTELCAKLIAAGAPGLHFYSMNQAALTTEICQRLKLA
>A0A7Y6K5A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia youngii|TrEMBL
MNPIELSFEFFPPKTQEGIDKLRATRAQLVSLKPKFVSVTFGAGGSTQQGTLDTVIDMAK
EGLEAAPHLSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARQLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCQRLVDAKVPGLHFYTLNAATSTKAICERLAV
>A0A6N7NX65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. MY15|TrEMBL
MPAGTSAHAEAFINAFSLEVSAKAMPALRAEADRIPRGTVISIPWLASEDDDARLAAVRT
VRALGFEPMPHLSARRIRSAASLARFLERAAGDAGVARCLLIAGDLATPAGPFADSASII
QTGLLEHSGIKVVGIGGHPEGHPVMSSDERWQALERKCQSIEARGMAPLIVTQFAFDADA
VLAWLDALRARGISVPVLVGVPGPASVSRLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVKGLTRAHGQVSPHFFPFGGVAPSLEWVAQYRRRISGTDG
>A0A5B9EFM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terriglobus albidus|TrEMBL
MVETSESLLETLLAPGRTVLCDGAMGTMLYARGVFINRCYDELNLSQPDLIRSIHEEYLH
AGAEMIETNTFGANAIRLARYGLADKVSAINHAGVALARKAAQHSEEKTATHAYVAGAIG
PLGARLAPAGTITAQQAHDAFAEQIAALAAAGADLLIAETFPSVAEAEIVVRAARDIAPH
LPLFVMVTVDDNGNTLDGTTAEETATRLTIAGADVVGCNCSSGPHAVLDVIERMRAVTHL
PLAAMPNAGLPRAVDGRNIYLTSPEYMASFARKFAKAGATFIGGCCGTTPNHIKAMRSAL
RAIDAQVTAKAEVTDETQAAVQPPAFGERSKLAGLLANRQFVSMVEIVPPLGVNCQKELD
GAKKLADLGVHVINVPDSPRASARMSAQSLCVQIQHKIGIETLIHVTCRDRNLLALQSDM
LGASSIGLKNVLCLTGDPPKLGNYPDATAVFDVDAIGLVNVLRNLNHGLDLGKNPIGESA
AFAIGVAANPGVPDVDNEVHRFALKVEAGAEYAITQPVFDMRLLETFLRRVEQFRIPVIA
GIWPLTSLRNAEFMKNDLRVAVPDEIMFRMHKAGEVSADHARAEGIKIAQEMLAHTRPQV
EGVQVSAPFGKYTAAAQVLELLN
>A0A0E1R8H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes serotype 4b str. LL195|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDDVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A8F6D984|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas indicatrix|TrEMBL
MSAGVGRMEPLAQTFVNAFSLEVSAKAMPALRAEAARIARGTTISIPYLPSEDDAARLAA
ARRVHELGFEPMPHLSARRIGSRAALEHFIERAVIDAGIERCFVIAGDLATPAGPFADST
SIIESGILERAGIKVVGVGGHPQGHPVMTSAERWRVLENKCQRIEERGMAPLVITQFAFD
ADIVLAWLNELRARGITHPVLVGVPGPASIARLVRYAAMCGVAASTSMLSRYGISIGRLL
GRAGPDVFVDRLAEGLTEAHGQVSPHLFPFGGIAPTMEWVEHYRMRAGDAHTTRSPVADE
PS
>A0A520Y9X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium|TrEMBL
MTVQHPSPLFEHTAGDVEVSFEFFPPKTDKAQEKLWSVIGELAPLGPRFVSVTYGAGGST
RERTHETVKRIVEETPLTPAAHLTCVNASRDEVQDIARAYWDAGVRHIVALRGDPPDGER
FTPHPDGYANAAELVAGLKEVADFDISVAAYPETHPEAQSSDSDIDHLLRKIDAGANRAI
TQFFFRPDAFFDLQEKVAARGRQVELVPGILPVTNVARTRQFAQQCGTAIPDWMDKKFEG
LDDVPRARDLIAATAAAELCGRLYAGGVRHFHFYTLNRAALSWAICHMLGVKR
>R5GQD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium adolescentis CAG:119|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVDEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREKRPDLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCESRVPEKLAVLLDKWGSDTALLKEAGIAY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A2G0YP10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas viridiflava|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKADLRGLLSQYKEAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFY
FVERVQKLGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQSFG
EEVITEMCERLLQGGAPGLHFYTLNQADPSLAVWNNLKLPR
>A0A397GGI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus thermomutatus|TrEMBL
MEKITDKIAALPPDENYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRGLIDKALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCLGVAAYPEGHPVDSYQDVQDPVRDLPYL
VEKTQAGADFIMTQLTYDIDAYTKFEKMLRNHESGAFKTIPIIPGLMPIHSYKILTRTTK
LSHVRIPPPIMSKLEAVKHDDDAVKRIGVDALSDLVEAIRKIPCPGFRGFHFYTLNLEKT
VSFIIERCGLIPDDPEDSDAVADDDYATAPTGVQIRSLYRRRASSINSQPHNRVIVDRLQ
MPSDNSSRASTTHEAPATSAGMPAMPPDRNTTLQISEGLGALGREATWDDFPNGRWGDAR
SPAFGEIDGYGPSLHVSATVARRIWGYPMSREDISTLFRRHVSGDLYIVPWSEGGAEENS
SGLNAETAVIRPELLKLIDGKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEF
FCPTKDFQTVLKPLFAKHGHEKLAWFATNAKGEFDSSLPANPADADTIEMNPNNVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAYRIWDEWRRIYPRGTPSERFLDEVKNDVWLVCVV
GQDFGAGTENGSEEEQHETKWMWDVLINSQ
>X7EJ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivivax halodurans JCM 10272|TrEMBL
MPRPDISLEFFPPKSLEASFRLWDTVQTLSPLGPRFVSVTYGAGGTTRELTRDAVKAIHK
QSGLRTAAHLTCVNATREETLEIARGFWDVGVRDIVALRGDPPKGEDRFTPTDGGFQDSC
ELIEGLKAERDFTIRVGAYPDVHPNAGTQQDDVDYLKRKFDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGIFPVENWKGARRFAEACGTKIPQWVIDAFETAERDGRSDLLAT
SLCTELCSDLIEGGVDKLHFYTLNKPELTRDVCHAIGVTPETRLENVA
>A0A077M5P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetrasphaera japonica T1-X7|TrEMBL
MSNAYPSTELHRLLSNPRYEVLPTPSIEEQIRAHIPTGLTVTVTASPAKPIDTTIELATT
LAAAGYDAVPHLAARMIGGRGQLSEIVERLTAAGVSKVFVPAGDAKEPAGEYVQSLDLLR
DLDFLGRPFEQVAITGYPESHPSIDDDVTIQSMWDKRTYATHIISNMTFDDARLATWVER
IRRRGIALPLYVGVPGPVERTKLLGMATKIGVGESMRFLKKQKSIFARIAAPGFGTDSFV
HRVAALAANDALGIAGLHLFTFNQVEATENWRQRLLRA
>A0A1N6SGJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter lappiensis|TrEMBL
MKITEHIANAAGKTLFSFELIPPLKGQSIQGIYNAIDPLMEFKPPFIDVTSLREDYIYKQ
HSNGLLEKLSYRKRPGTIAICAAIMNRYKVDTVPHLLCGGFTRDETENALIELEFLGIEN
VLVLRGDARNSDSSFVPTPNGHAYATDLLQQVVNMNNGVYLHEDYDNIAKTNFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGASFIVTQMFFDNQKYFDFVNNCRANGINVPIIPGLK
PITTSKQLVNLSKTFHIDMPEDLCDAIHACKSEKDVKDMGIEWMINQCKELVKFGVPVLH
FYTMSNAGPTKRIAEAIF
>A0A3T0N474|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasedimentitalea marina|TrEMBL
MTTPEISFEFFPPKNLEGSFRLWDTMQVLSPLEPRFISVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVDATRAETLEIADQFAAAGVKDIVALRGDPPKGAGGFTPHPDGFASSV
ELIEALAVSGRFNIRVGAYPDRHPEAASSTADVDWLKRKIDAGAGEALTQFFFEAETFFR
FRDKCAKAGIDHLLTPGILPIENWKGARNFANRCGTVIPAWVDDAFNKAIRDNREDLLAT
AICTELCSELLDGGVEKLHFYTMNRPELTRDVCHALGVVPKVSLENVA
>A0A1G8DHE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter terrae|TrEMBL
MKITDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QANGLLQKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHCYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMSTDFKYLKKKVEAGAEFIVTQMFFDNQKYFDFVKKCRENDINIPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNNEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKQIAKAIF
>A0A397H029|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus thermomutatus|TrEMBL
MHVKDKLAENEAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALSAAYKAGCTNILALRGDPPRDKEA
WEATEGGLRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSSF
VITQMFYDTDIFIEWVKKCRAKGITVPIIPGIMPISTYAAFIRRANWTKATIPPDWLEAL
EPVKNDDAAVKEIGKRLIADMCRRLLAAGINHLHFYTMNLAQATQSVLDELKLIPSEETP
LQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQIWDEFPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSIRDVTQIFVRYLEGELDRLPWSDSPISSEANVIKNSLVQ
LNSRGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNE
DLTYHAVGKKGELRTNTRDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRLGEDWA
KCHDAGSPSRKLIQDMMDNWYLVNIVNNDFHNTYDLFELFNDLDVKDLDLEVVPDKVESK
PQPNGAAHEEVAAKN
>A0A3S2WCR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. CNPSo 2736|TrEMBL
MIIKRITHKLPDISTASIIPASIEASPAQVLGSTDLAGLFPQGVRVYLTDTGAASQERVV
EAAGHLRDLGYEPVPHLAARRIPSRAAFEEQVKRLAGEAGVTDVLVVGGGVDRPAGSFAS
SMDMLSTGIFDRCGIRQIAIAGHPEGSPDFNDETAMAALRLKRDFAERSDAAMRIVTQFG
FDPARFIAWAEGLAASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESIVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGAVDRSAS
PDSMAG
>A0A5D4RCY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus infantis|TrEMBL
MNLLDKMEKEIIIADGAMGTLLYSYGTDFCFEELNVSQPEHIQNIHQAYIDAGATLIQTN
TYAANYLKLQRYGLEDHVKEINSAAVAVARKAAGKNAFVAGTIGGSRGIKPHSISIEEIK
RSFREQLYCLLMEGVDAILLETYYDLKELETVLSIARKETALPLIAQVSLQETGIMQDHT
PIREALSRLDTLGADIVGLNCRLGPHHMLLTLEEVPLPQKAYLSAYPNASLPAYTDGKFH
YEGDAEYFRQSAKAFRNQGVRLLGGCCGTTPAHIRAFSQELVGSPPLEKKKVREPKAKIK
ILPKEAQRDFPPLQDFVKERQSVIVELDPPRKLDTDKFFAGAKALQDAGIDAITLADNSL
ASPRISNEALGYLAKNRLGLRPLIHLTCRDRNVIGLQSHLMGLHTLGLHDILAITGDPAR
VGDFPGASSVYDMSSFELIQMIKQLNEGRSISGKDLGQKAAFSVAAAFNPNVRSLEKAVQ
RLEKKASYGADYFITQPVFSEEKLMEIYEATKHLEQPIYIGLMPLTSSRNADFLHNEVPG
IKISDKIRERMNSLKDDPLLSVREGISISKELIDAAAELFNGIYLITPFMKYELTAELAE
YARSEKLKTARRSRNAKDLSI
>A0A0M4UN43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus schleiferi|TrEMBL
MSRLLKALQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVEHIHRSYIEAGADVIQT
NTYGANFEKLKPFGLEHKVKAIHQAAVAIAKRAARPDTFILGTVGGFRGVKQGELSLSAI
QYHTEIQVDTLIESGVDGLLFETYYDLTELIRVITQTRQNYNIPIIAQLTASNTNYLRDG
TEINDALQQIVAAGANVVGLNCHHGPHHMKHSFSHIALPDKAYLSCYPNASLLDLDQHTF
KYSDNAQYFGDTAQQLIQEGVRLIGGCCGTTPEHIRHIKSAVKGLKPIQNKKVIPIDKKR
ETLAQNQHQLNLADRVRQKPTIIVELDTPKHLDTTKFFNNVKALDEANIDAVTLADNSLA
TVRISNIAAASLIKQRFDIEPLVHITCRDRNLIGLQSHLLGLSLLGIHEILAITGDPSKI
GHLPGATNVYDVNSKGLTELALKFNKGINTDGDALKTTTQFNIAGGFDPHVRNIKAAVRK
METKIESGMSYFITQPVFSKEKIIEIYEATKHLNVPIFIGVMPITSYNNALFLHNEVPGI
KMSEEILEQFKAVASDKEATYQLSISLCKSIIDTVHTYFNGLYLITPFERVDYSLELAAY
SKSITQTHQEAIL
>A0A6N0Z860|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter sp|TrEMBL
MTKTVPTFSLELFPPQTREGAEKLRAARAQMALLKPRFFSVTFGAGGSTRDRTLETVLEI
QHEGHQAAPHLSCIGSTRASIRSILEQYRVHGIRHLVALRGDLPSGMARPGSFRYANELV
EFIRSETGSWFHIEVAAYPEYHPQAKSPVDDLLAFKRKIDAGADSAITQYFYNFDAYSHF
IDECGAIGINVPVVPGIMPISSFSSLARFSDNCGAEIPRWIRKRLESYGDDRASIHAFGL
DVVTRLCERLLAAGAPGLHFYTLNQVDLTRTLWQRLRLAPAGEA
>A0A7Y7M399|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. SDTb3-6|TrEMBL
MSPPPPALAPPGASAPIALSYELFPPRNPTASASLWDTIRELEGTRPDYVSVTYGANGSN
RDTAVELLNRLLTESTLRPLAHLTCVGNTAAELAGIISELLDHGVRGILALRGDLPRDPA
GIPQAGSPRYAQDLVELIRRVEQGRSALLCAGRVAIGVAAYPAKHPESPSVEHDLEVLLA
KQRSGADFAITQVFFHAEQYRDLVVRARRAGVTIPLIPGVMPLTSLRRLKRLAELTGVEP
APGLLDALGRAADATAARRIGVAATVDLARAALDAGAPGIHLYTFNEHAAALDVLDKLQL
PRPAPLRRPAQPELVRA
>A0A0T2ZFE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp. Root209|TrEMBL
MGLPVSLEFFPPKTPEGVDKLRAVRQQLYGLKPEFCSVTYGAGGSTQEGTFNTVRDILAE
SVPAASHFSCIGATRASVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLVSFI
RSETGDDFHIEVAAYPEVHPQAKSPESDLQAYATKVRAGAHSAITQYFYNSDAYFRFVDD
AFKLGADVPVVPGIMPITSSTQLMRFSDASGAEIPRWIRLRLQAFGDDTASIKAFGLDVV
TDLCDQLRNGGVPALHFYTMNQSVATLEIAKRLQLS
>A0A1V3H270|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinivibrio sharmensis|TrEMBL
MSYTHAGHIDALNQNIADLDGDINVSFEFFPPSTPSMEETLWNSVHRLKALKPKFMSVTY
GANSGERDRTHDIVKSIHDQTGIAAAPHLTCIDATEDELRHIARDYWQNGIRDIVALRGD
LPSPEKKPDMYAVDLVRLLKEEHDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAKMTNVRVPQWMHKQYQ
GLEDDPVTRQMVGASIALDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPLAVAP
>A0A2C5YW68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps camponoti-rufipedis|TrEMBL
MAPLPTNGHKALPHRQRDDSRLSVQPPVMAVDKITHKIAALPDGVDYFSLEFFPPKTAMG
FANLRHRLQRMEQALRPLFVNVTWGAGGATAIKSLELAELCQRELGLTTCLHLTCTNMSR
RLIDKTLEDAKVLGIRNILALRGDPPRKEEYREAMADDYNQDDNSVDFEWAIDLVRYIRS
KHGDYFCIGVAAYPEGHAIGSHPEVQSLEHDLPYLVDKVRAGADFIMTQLFFDADAYEKF
ERTLREHPSGAFATLPIIPGLMPIQSYQMIKRTTKLSHARVPDAFMARLDAVQGDDERVK
KIGVDIICELIEQIRAMGGGRSGRRGFHFYTLNLEKSVSLIVEQTGLIQEDSSDEAVSDA
LLSPPPTLHVNGNGPLRPGGGHSRSSRRQSSVGSDPHNRVIVGDRPLTNPEWETTGQEAG
VPASSVNSRANTLAISEGEGVLGREATWDDFPNGRFGDARSPAYGEIDGYGVSLHMSVTQ
AERLWGHPTTREDIDGIFVRHIRGELAAIPWSEEGLMAESSTIKDQLVELNSRGWWTVAS
QPAANGAPSSDRTVGWGPTNGFVFQKAFVELFLPASEWRTLWERLQRPGTRDSICFYAAN
ARGDFASSDESGGSKDAGSAPSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWGE
WARVYGRGSASEKLLRGIRDDYWLVNVIHHEFVERDGLWDLLLGRE
>A0A1D2SGA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lautropia sp. SCN 69-89|TrEMBL
MDLGHATAGIVRLARNASIETSTRNVAEVNGYARMLPPGSDVYITFLPGTPYHHILSTAT
RLRQVGLNPVPHLAARRFASAAAVADFLARLRDEAGVTRVLLVAGDSDAAAGPFDSSLQV
LETGVFEACGIRSIGVAGYPEGHRRIPQQALDDALERKIRYAEAHRLELFVVSQFCFEPQ
RVLDWLGRLRARGVTLPVRVGVAGPATVRTLLAYALRCGIGASMKALGSQPVSLNRMLAR
HGPDDFTRAIAPRAAELGVTGLHLFAFGNFADCAQWIRDAAAGRIGPEKDSTESAARG
>A0A0F7LJ40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus thracensis|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSIGRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWNNGIRHIVALRGD
LPDNSEKPKMYGADLVELLKKEADFDISVAAYPEVHPEAKNSQADLICLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQLKRFATMTNVRIPSWMTRMFE
GLDDDPESSNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A0F2N9T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium BRH_c16a|TrEMBL
MSFQKRLAAKEFAVLAEMHTPKGINISRLVNDARRLKGRVDAVVIPDMDNGIMRMSALAG
GVLLQQQGLETIMHTYCRDRNRMALQGDALAAYVLGIQNLIVAGSEDMSESDHSDAKTVN
DLDEVRLIEVLMTLQKGKDMSGFDLDGAPDFTIGCTISPCADEKACNTALAAAKKKIAAG
AAYLITPPVFDLAAHTVFLGKVKELGVPVIATVFLIKSLAIAQYIANSDPSARITDDLIR
RIRKSSDRELEGIKIAGETILAMKDLTQGVLIQTLGWEHKLPEILDVAKV
>A0A533R0I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter sp|TrEMBL
MTKTVPTFSLELFPPQTPEGAEKLRAARAQMALLKPRFFSVTFGAGGSTRDRTLETVLEI
QHEGHQAAPHLSCIGSTRASIRSILEQYRVHGIRHLVALRGDLPSGMARPGSFRYANELV
EFIRSETGSWFHIEVAAYPEYHPQAKSPVDDLLAFKRKIDAGADSAITQYFYNFDAYSHF
IDECGAIGINVPVVPGIMPISSFSSLARFSDNCGAEIPRWIRKRLESYGDDRASIHAFGL
DVVTQLCERLLAAGAPGLHFYTLNQVDLTRTLWQRLRLAPAGEA
>X6IFF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L2C066B000|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>R5NF76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraprevotella clara CAG:116|TrEMBL
MNVIDLIQNHKGTAFSFEVLPPLKGAGIDRLFHTIDTLREFNPAYINITNHRSEYVYKDL
GGGIMQRLRIRRRPGTIAVAAAIQRHYDIHVVPHILCSGYTREDTEYMLLDLQFLDISDL
LVLRGDKAKEDPAFRPTGDGYSHATELIEHINRFNEGFFVDGSPIKSPGTSFSYGVACYP
EKHEEAPNPEADLAVLKQKADMGAAYAVTQLFYDNAKYFDFVDRARRAGITIPIIPGIKP
FAKLSQLNVVPKTFHCDLPQALALEIGKCKTDEEAKQVGIEWTVEQCRELIGHGVPSIHF
YTVSAVDSIREIARQIY
>G8JM58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582)|TrEMBL
MYRIIDLYDEIEGPAISLEFFPPKTEPGKNNLLARMARMSAMHPLFVTVTWGAGGTTSEK
TLELAEFAQRDMNLTVCMHLTCTNMDNSILDAALRRAKEAGIKNILALRGDAPVEENFDS
TGAGLVQFRYAVDLVRYIKTNHGNDFCVGVAAYPEGHCEGEADGREQSPLRDLPFLKEKV
EAGADFVITQLFYDVEKFLAFEELFRKEVSATLPLFPGLMPVNSFLLFNRAAKLSHASIP
DSVLDRFPHHVRGDDMQVKEIGVQVMVDIVEQIWTRTNGRVKCFHFYTLNLEKSVANIFA
SSKILSTIAEDESASEIDVEADGDLTIEDGKTESSENLKKRRRQSSMNSERPYNRVILTE
GHNFDLKCNGAPPRKVVLSISQGSGSLGRDATWDEFTNGRFGDSRSPAYGEIDGYGPSMK
VSVKRAYNLWGSPKCLQDIITIFTRYLESSIDTLPWCDLGLSPETALIQEELIELNNRGY
LTLSSQPSTNSSSSSDKIFGWGPADGVVYQKAFVELFVQKHAWENDLKPRIETSSGSFSY
YLGDSSGHFDSNMEPQSANVVTWGVFPNSQILQTTIIEEESFKAWRDEAFSIWLKWSQLF
PRNTPENTFLRQMHQDCYIISIVYHDFTDFDGLWSTLLD
>A0A0X8P0J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MSSLKQALDEGRFACVLEVIPQQSPARLAALEPIVQRGRLAGWPLLPAFADRVGLHSDLS
PLEGAAALDDPPACLLHFSGKDRERADLLRQMAAMQARGLKQLLMLSGDRLPGHQPGQAP
VRYLESVPALQIAREHGPDWLLGAALNPFKYREEEGAAQYLKAQKKLLAGADFLTLQLGF
DAAKHLEAQAWMRAQGRGKPMLACVMQLTARRAAVLQDVPGIVITDAMRELLHKEQQLSP
AHASARSLDRLALQIVGLQWMGYAGVHLSGVHTLDELLSLEQAIARQRDAVTSLSDWVER
WQASWRMPGMPEVCFAPDTDTWALGQSDVAATPGERLRYALLSTVHEQLFNRTGWLGSAF
GWSVTRPFWKTGVAAQALHAVERTLKRPLVGCDTCGTCRLQDTLYVCPETCPKGLANGPC
GGTRLNRCEFGDRECVHSVKYRIAKSADQLPALAQTLIPGIEAGDRHRSSWPAWFKPEDP
TPGNDCRSLPKSG
>A0A7V0I8J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Acetothermia bacterium|TrEMBL
TLGDHPGARPVFDLDSVQLLATIEALNGGKDLAGNELQGAPDFFAGAVVNPGVEPLGPHI
LKMRLKVKMGAKFFQTQAVYDPDAFLKFVREVEDLKVPVLVGIIPLKSARMARFMNENIA
GINVPEGVIAEMERAKTKEERKEVSAEICARIIRKVKPYCRGIHLMPMGWEDLVPNILEL
AGINP
>A7TAZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nematostella vectensis|TrEMBL
GKSLFSFEILPPLKGQNIQSIFDGIDPLMEFNPPFIDVTYHREEYEFKEKGNGLLEKKIV
KKRPGTVGICAAIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDNVVALRGDAVKS
EIYFKPDKDGHSYASELVTQIRNLNNGIYLDEDLQNSTKTDFCIGVAGYPEKHMEAPSID
SDIHFLKQKIKNGADYIVTQMFFDNKRFFEFVTKCRVAGITVPIIPGLKPIATKK
>A0A1R4A7D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cuniculiplasma divulgatum|TrEMBL
MISMVNFKESLNNLPLIFTVIPLRDSKTGDPEHDNRIVKNIEARIMDISKTLSDFPGLTA
INVPELVEENHEGKPRYNSIFTRKLARGIADQLGKEAIINKVVAHMESYDEFANWILETE
SQGIRNIVLVGGNTRHHRYTGPNVSEANLITKHLMKTKNLNDITIGNICLPERGGEARRM
LYKTISGADFFTTQMLFEGDHITHLLKEYGELCSKAQVNPATVILSFAPLKSVADLNLLD
FLGVDLPDETKDYILENEQVSKAYKRSIKNALDVLKAIMNDKIDNYPEINIGINVEQLTK
SNMPYSIEMLKEFHIMTQKK
>A0A0M5JL76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus gobiensis|TrEMBL
MGLIEDLQKKILIADGAMGTLLYSYGIDRCFEELNISQPEAVRGVHQAYVNAGADIIQTN
TYGANHIKLSRYGLEDDIKKINAAAVQLAKAAAEQAYVLGTIGGIRTFNKSAHTLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAQEVLKIARKETDLPIIVNVSMHEQGVLQDGTS
LADALASLEGLGADSVGMNCSLGPYHMIQSLEEVPLPKHSYLAVYPNSSLPALEEGRLVY
ETDTDYFGESALKFRNQGARIIGGCCGTTPAHIKAMSEAVKQLHPVTEKSVKVKKTDPVH
VQDIREEPSLDELAKQKRTIIVELDPPKKLNFEKFLHAASELQAAGIDALTLADNSLATP
RISNVACGALLKQKLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLQDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGVSYSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIECGADYFISQPVYSEEQLYKIYEETKHLTTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDEIREAMAFAGEDKQKQAEEGLSIAKSLLDTACELFNGIYLITPFLRSDLTSELTTYIH
QKKKEIHHVHDHQ
>A0A1N5UNL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cuniculiplasma divulgatum|TrEMBL
MISMVNFKESLNNLPLIFTVIPLRDSKTGDPEHDNRIVKNIEARIMDISKTLSDFPGLTA
INVPELVEENHEGKPRYNSIFTRKLARGIAYQLGKEAIINKVVAHMESFDEFANWIVETE
SQGIRNIVLVGGNTRHHRYTGPNVSEANLITKHLMKTKNLNDITIGNICLPERGGEARRM
LYKTISGADFFTTQMLFEGDHITHLLKEYGELCSKAQVNPATVILSFAPLKSVADLNLLD
FLGVDLPDETKDYILENEQVSKAYKRSIKNALDVLTAIMSDKIHNYPEINIGINVEQLTK
SNMPYSIEMLKEFHIMTQKK
>A0A1P8EC16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. B29|TrEMBL
MKIIDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTEGGHAFATDLLEQVTDMNKGKYLHEDIITSEKTDFCIGVAGY
PEKHFESPNFNTDFKYLKQKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVSACKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLA
>V4I168|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PVA_94-07|TrEMBL
MRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSVTYGAGGSTRSGTVRA
TRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVRHP
EGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVDKCRAGADYAITQMFF
DPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVFPRKLEERMRAAADDP
AAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLGLHDDKG
>N8YME8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter venetianus (strain ATCC 31012 / DSM 23050 / BCRC 14357 / CCUG 45561 / CIP 110063 / KCTC 2702 / LMG 19082 / RAG-1)|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIKRFVEKVQAGANAGITQFFFNPDAYFYFI
DRLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A659K8E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E4208|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A494WVR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofundulus salinum|TrEMBL
MKTESKLQKLLDSGHFAVTAEIGPPKHASAHGIRHHAHMLKDYVDATNITDCQTAIVRLS
SIASAVHILDCGLEPIVQMTCRDRNRIAIQSDLLGAYSLGVRNLLCLSGDHQKFGNEPSA
KNVYDIDSIQLIYLMRRMRDEKLFFSGEPIKEHEPRFFIGAVANPFADPFEFRVARLEKK
VEAGAEFIQTQCIFDMERFERFMEMVRERGIHERVHILAGVTPLKSWRAAKYLQTSVSGM
IVPDDVVERLKKAEDPKREGIEICIEQIKHIRNIPGVHGVHIMAIAWEEVVPEIVERSGL
FPRPKVE
>A0A7K0YAV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPVCPLLRKTSAGPFETVTEALGTRSGRQEPSLSFEFFPPRNQEEAADQLWRSFDALMEV
SPDFISVTYGAGGSNRETSLAVVERMARDVMTIGHLTCVGGSRASTAETISRFEDAGVHS
ILALRGDAPQDNPDALKTGELKSALELVHLVRQTSNLEVGVAAFPEVHPESPHMEHDSMV
LEMKQSAGATYAMTQLFFTVDAYTDLVSSAKIAGATMPIIPGLMPVGNAAKVLRMAEMSG
AAIPVELLKELENAGSDAEARVIGMEYSIKLARDLVDAGAPGLHIFSMNLSKAALEVARG
AGLCR
>A0A7V1RIT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTSRLERLVRAGTFVVTAEVVPPRSADGGAVRAQARELVGYADAVNVTDNPRASAHMSPV
AGAAFVAAAGLEPTMQIACRDRNRLGLAADLLGGWALGARNLFCLTGDPLAVGDEPGAAA
VHDLAVEDLVRMAAELRERGRLPSGAEIDPAPRYFIGVADVPLAPGYDPARLERKLDAGA
GFVMTQIAYDLEALRVWLELARARGITERAALVVGVAPLASAKQARFLHEKVPGVSVPAE
SLAELEDAGERAPEVGVARCVELVRALRDTPGVAGVHVMGLGREAAVRAVIEGAGLLPRP
PAPG
>A0A8I1S868|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVTVREQLATAGPHFSVEFYPPRSNDEEAILWTAIRQLEARRPAFVSVTYGAGGSHRDRT
IRVTEQIAARTTLIPVAHLTAVGHTVAELRQILGAYADAGVRNILALRGDPPGSDPFAPW
VATPGGLTHADELVRLTRSLGDFCVGVAAYPTKHPQSPDAASDIRYLAGKVAAGADFVIT
QMLFSAEDYADLVRRARAAGVRVPIIPGIMPVTSLARLNRICQLSGQQVPANLAQTLADV
ADDPAAARSFGFNHALAMCRDLIAMGAPSLHFYTFNRATMTLALLDRLRIGATGDDATAV
DHALDRSVDHSVTPVR
>A0A6I3CBW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVVTSTTVQGITPRAPGAVATMSIFRSRQRSGTVDEQPSAPGIVDRVTHAHLELIPTPKA
HLQFPELPEASTVSVTCSPAKDIQATLDMAAQLQDLGHTVIPHLAARMVEGPEQVATIAQ
WLNAHDVRDVFVIGGDAPDPHGPYLDAGALIEALLNSNANLANVGFGGYPEGHATIPLNK
LADAVATKQQLLDTAGVGGWVSTQMCFDTKAVSKWIQHSRSQGLHLPIHLGIPGVIDTTK
LLTMGAKLGIGASLRYLRKNRAVVSK
>A0A7J9WUI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGDRKVPSPPEPPPSFLQREDFSILCEIEPSRKPNIDHVRTQIDVLNPVVNAFLIPDNHL
GRATVSSVAVAHEVAYMGGHSIACINARDRNLLGFRRDLLTAAAYGVDHFLFVYGDAPKE
GRRTDDLSVRGMISEVRNFGTGALFEGYADFKIGTVAKTGRPITWRAAADFLFVQITYAP
HRLMEWRNELNFNGGVYAGVLVLASARMARRINATIPDIRIPRRIIDKLESDPDYGIDFA
LEQIETVRDSGLFDGVHLVPVTRFRQIAERLRSFDRRRPA
>A0A7W0UFU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSHRFVERLRSGTPLVADGGMGTLISGAVPRLRCPEEANLRAPESVVALHASFIRAGADL
IETNTFGANRRKLSALYLEDELEQINSAGVRLAREAREVCGGEVFIAGAIGPLGDAELFS
PADGAPLVVEQAQVLEGRGVDLIMLETYYDLDEIVAAIEAVRSVSKLPLVALMTFDADGQ
TLGGVSAAAAAEQLDKLELAAIGANHSAGPAAALNALAEMRRDGLVLAALPNVGLASLAG
SRVVFPHATPEYFGEFAAQARNLGARLIGGCCGTTPAQIAAIRAAVDEGREPTQQLVARE
RELFVPTESAAEETQLARMFREGTFVVSVQLDPPLGASNKALLETARVLKGHEGVHLVDV
NDNPRARARMSGVMASVAIERNCGLETIPHLTPRDMAIAGLESLLLGAHAEGVRNVLAVT
GDPPEEGDYPGTRGVYELEAIGLTRLIAGLNRGEDYHGRSIDAPTSFFTGVAVNPSADDL
ETELDRFEQKLAAGAQFAMTQVLFDLTFLEAFLAHHGGRSPIPLLVGIWPLRSHQLAVRI
HNEVPGIVVPEPVQERLRVAGPDAVDVGLELARELMDEARERAAGVYLVAPFRQPLGILD
LLT
>A0A7V6GLZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MHLKKKPLIFDGAMGTYYVSAGKSKSLKCELANIYDSETILGIHREYVKAGAQAIRTNTF
AANEYYLECDWKTTKEVIEKGYRLAHEAAKDTDIIVFADIGPISVPDLSDLFEEYKREID
LFIELGASSFIFETFSNDTAVLKLSKYIKEINPNSFILASYAISPEGFTRDGASGSALIK
RASESPDIDACGFNCYSGPYHLMKYIKNLDISNKSISIMPNSGYPEILSRRTFFNGNKEY
FSDIMMEIIKSGVSIIGGCCGTTPEFIKEIVGKLQDINENLSAAETGRKAESKRKKISSN
LILKKINDGKKVIAVELDPPSDTNIDSFFENAKILKKHNVDAITIADCPIARARVDSSLL
ACKLKREYGINSIPHMTCRDRNINATKALLLGLSIEGVNNVLLVTGDPIPSNQREEIKGM
TGFNSARLAEYVTNLNETVFSPPFNICGALNINSNNFAGQISHARKKIESGISMFLTQPV
LTEQAVKNIEIARNELKSKILGGIMPVVSYKNACFMNNEIPGIKVSEEIIEIYRHADKGE
AFRLAVDISVKYAERIYPHVDGFYIITPFNRADIIVEIIKKLDDLIASS
>A0A0A3I3F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ureibacillus sinduriensis BLB-1 = JCM 15800|TrEMBL
MGFLEALKTQVLTADGAMGTLLYAYGLDNCHEEMNIIKPDLIEKIHLEYITAGADVIQTN
TYGANAIKLARYGLQDRVTEINEVAVSLAKKAVGTGNQFVLGSIGAVRGVRKSDVTLDEI
LTAIKEQAKVIIDGKVDGLLLETYYDFEELTETVKMLREETSLPIVAQVSMHDPGILING
MSLNDALKQLEKLGADIVGVNCRLGPHHTIQAFEGVELPENAFLSAYPNASLLDIEEGRV
IYESEIDYFARAAVQLRNQGARLIGGCCGTTPKHIEAAKKRLQYMQPISVKKAKVQKEIF
IQEADPTILEPLHEKVKRERSVIVELDTPRHLEIEAFVEGAKTLYSEGADIIMMADNSLA
SPRVSNIAMGSILKLQHGIRTMPHITCRDRNLIGLQSHLMGLNALGLHDILTVTGDPTKV
GDFPGATSVYDVSSLELISLIKQLNDGISFSGKPLRKKSNFSIAAAFNPNVRVLERAVAR
LEKKIEHGADYFISQPVYTSEKIIEIHEATKHLSAPIYIGIMPLTSFRSAEFLHHEVPGI
KLSEEVLNRMESCGGDSEKETAEGIAIAKELLNTAAKYFNGIYLITPFIRYEMTIKLMQY
INQLDEQNKGVKANV
>A0A7K0YAE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MLNKQVRVSFEVYPPRDQNSGESLESSIIELAKMDPTFISVTFGAGGSSTKNSLEVLKYI
LQNTQAAALAHLTCVGHSFLETKALVNQFMDEGISDFLALRGDPQPGMPVEPKGELKTSS
ELVQLISQVHKDRGNSRSALNVAVATFPNGHPDSDSIAQDIQALLAKQNAGADYAITQLF
FFASDYVAFVKLAREAGVTIPILPGIMPVTSMQRLNRVIELTGEKYPEALAKQLSVTSKE
EAKQAGIDWAANLVAELVEQGAPGVHLYAFNQHESVTQVLQRAGIR
>A5D3I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI)|TrEMBL
MNAGSRLEQVLKSGRLAVTAEISPPKHSSPEGIINLARILKDWVDAANITDCQAAVVRMS
SISAGIHILQNGLEPVIQVTCRDRNRIAIQSDLLGAYSLGMRNLLCLSGDHQSFGNHPAA
KNVYDVDSVQLIQLVRRMRDERKFFSGEEIKKCEPRFFIGAVANPFADPFELQVDRLEKK
IEAGAEFIQTQCIYDMERFARFMEVCVRRGLHERAYILAGLTPIKGLRSVSYMRTIPGIT
VPDEIVSRVKNARDQKAEGINICIEQINYIRKNIKGISGIHLMAIAWEEIVPEIVKRAGL
RRE
>B5ED55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrifermentans bemidjiense (strain ATCC BAA-1014 / DSM 16622 / JCM 12645 / Bem)|TrEMBL
MGGSFLERVAHEVLIGDGAIGTMLYAKGVALDANFEHLNLVRPQLVLDLHAEYLAAGAQV
IETNTFGANYAKLSAIGIGGKVADINRQGAILARRAAKVRDVFVAGSMGPMGRGKQEMSA
DQVRDSFRLQAAALAEGGVDLLILETFSELDELETALSAARETGLPVVANLAFGEGSRLA
GGIEAEDAALRLAAAGASLVGANCGAGPLELLATLKRIAAVTDLPLAAYPNSGFPEYVDG
RYIYRTTPDYFAARAEEMVAAGAVLVGGCCGTTPEHIRVMAQRLKGARPAARVAVGAVSR
TPASEKAKTAASGFLDLWGKEMVVTVELDPPKGLDCSRILAGSRALKEAGADAINLAENP
LARVRMGNLALASLIRRDVGIEVIAHITCRDRNLIGLQSDLMGASLLGVSSILAVTGDPA
SLGEEAGASSVFDLNSFTLIKLLSDLNRGVNALGNPIGAGTGFTIGAAFNPNTQKMEVQV
ARLAKKVANGACFAQTQPIYDLERFEQMMEQTAHLGIPILPGVLPLVSGRNAEFLHNEVP
GITIPDGIRARMAGKTGEEGVREGLAIAREFIEATMGRVGGFYLIPPFGKYEIAVELVKF
IKSRAEHRGH
>A0A6I3GMH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPRIADILTQASGPTLSVEFFPPKTPVGDANLQQTIEDLRAVPLSFVSVTYGAGGSTRDR
TRDLVVDINEHESYPAMAHLTCIGHTKPELEALLDDYDRAGVHNILALAGDPPADGSPAD
GDFTYALELVELVRARGDHFSVSVAAHPELHPRSQDTKGDRLHLAQKLSVADFGITQFFF
SAPDYFQMVEELSALGCDTPILPGIMPLTNPEGVRRMAKMSGATIPEDLAVRVEGAGSVD
EAQAIAVEAALELSQELLDGGAPGLHLYGLNKSEIVLRLVDQLNLL
>O58818|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)|TrEMBL
MRILSCPKKLLNGPCGDVFNGTCRVSKKPCPWVYVLEKLDTLDGAPLLVEHPIVARFTLE
DDVEIKKSKFIKDLEKGRAISVEFPIRVFESGFKDFKDNGYLFTVPDNPLGYPHVSSVAL
ATWLKSKGFEVMPHVTGKDRNALAITSELRTAVEFNFEGVLLTTGDWPGLMLHAKPVFDL
DSTNMIKLARLVFSGILPTGEKIEVKERPFVAGTMNPNYQEKLEGKRLARKIIAGVDVVF
TQVVANVKVARKIPEIVKHSLKYSSREVPIVVSLLYPIKKELENALRSMGVEVGSKFEEV
LEEVSSLEFAGINLIVFADDWMEKVEEALELVKEVV
>A0A7K0ZKB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MREEGSGAGSDASRRSLGEVLSTGSRSFSFELFPPKTDDGERALWQTIRDLQGLSPSLIS
VTYGAGGSTRDRTVRIVGGIAAEPALTPLAHLTCVGASRDEVRAVVDEFAAAGVRAILAL
RGDPPGGPGSAWVQHQDGFAHADELVEFIASMGNFSIGVAAFPEGHPESANLADDAVVLA
RKQDAGAEFAITQFFFDARDYERLVRDAAGHGCTMPILPGLLPVTNVAQIERFAALSGAA
FPADLAARFALVKDDPDAVHALGVEVAAELGRELLEMGAPGLHF
>A0A6I2W461|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MIAELMTKSEPTLSFEFFPPKDESGEAALWSSFDSLLELSPDFVSVTYGAGGSNQAKSLA
VLTKMAARIPTIGHLTCVGATFPSTRATIGAFEDAGVAAILAIRGDAPRDNPDALSQGEL
KTALELVEQVTAHSEMEVGVAAFPELHPESPSLAHDVKVLKLKQEAGAKYAFTQLFFHVE
AYTALVAAARAADVTIPIIPGVMPIGNVKGVLRMAELSGASVPQELLIRLEGATDDENAK
DIGMAFSIEFAKALLAAGAPGLHIFSLNHHRAAEELARGAFSRLSR
>A0A1W4W6U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila ficusphila|TrEMBL
MAVSFRRSAIARVCLSMHTYSVTYEGSPNNTPGSSSYVPCLTFAPGQNESNQTVEQRIGP
LVAERTSRRRFFYGIEVTANEMGGGPPVCLNFNHFLPLLPTFVSVVWLNQRYWDVEPIGQ
VRSLQMAKHLATHIPVLPHLTAFRLSERRLNQFLDLNFSSILAVRGDQVHEDQRFRLALP
MIEHLRQQRENISICVGGYPEGYTNLGDFPPAFTKNIAFLKKKVIAGADCIITQICYDSE
AIVQFIKDCRAAGITVPILVGLTPHESFRSYLMMENVANVRLPTDLRRLLDDQRGIPIRD
TLTEEDPVKKFFINLTVKIVRDVLDADLGIWGFHFFTLNQFKLVQEVLQELRNLNVIEDG
DQNGKQD
>A0A285YTN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. LAIL14HWK12:I8|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKEELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEIDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLAIWNNLKLPR
>A0A538I5F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTNLNRAEDFNGRPIDAPTSFFPGVAVNPTPDDIGVEIEHFHRKVEAGAKFAITQIVFDL
EPLDRFAERLGGEWPIPVIVEVFPLTSHRLALRLHNEVPGIVVPEPLQHALQDAGSDAAR
LGFDHARRLVEEASRFAGVCLVAPFRRPLRVLELLA
>A0A4Y9PL56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. CT_GayMR19|TrEMBL
MTRTVRELLASERPTWSFEFFPPKTPDAEPQLWTALRELERLRPSFVSVTYGAGGSTREG
TVSVTERIATDTTMTPLAHLTAVDHSVAELRHLVSRLAAAGVRNLLALRGDPPGADPQAE
WIAHPEGLNYAAELVELIRSMGDFSVGVAAFPERHPRSPDFDSDVEMFIAKCRAGADFAI
TQMFFRPEDYLRMRDRVASRGCEVPIIAGVMPVTSARQITRIVQLSGQAFPPDLADRFAE
LDGDRPEDRAAVRAFGVEVATELCRTLLDEGVPGIHFITMNRSTATREVYANLAADPAVE
PDVLPASDSAIAAPIR
>A0A1H6JCV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epilithonimonas hominis|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFKPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEPSVGGHKYASDLVKQIHDLGIGEYLHGKIESDTDNSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKFFDFVKQAREIGIDVPIIPGIK
PIATKTHLQMLPQVFKIDLPEALINEVLKCKTNNDVREVGIEWAINQSKELLDFGIPVLH
FYSMGKSDNILKIGREVF
>A0A5C4XG13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium smilacinae|TrEMBL
MMNENTTHPRFEISFEFFPPKSEEMEAQLFETVERLALWQPEFVTVTYGAGGSTKEPTLA
AVTTIIKDTNLPTAAHLTCVDASKDDVHAIVEEYRAAGVRRIVALRGDPSAGIGTVYAPH
PQGFQQTADLVGALAAYGDFDISVSAYPEKHPESPDMSADIAVLKSKADAGATRALTQFF
FNNDVFFRYMDAVAAAGITLPVIPGIMPIQNLTQLKRFSKRCGATVPGFLDDRFDGFDDK
PEERAKVAADVAAEQIEELGKHGFKHIHLYTMNRAPLVSAVLENIGYKPGAARAAA
>A0A3N5LTZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
ALRLQKKIEAGADFVQTQCIFNVPKFKKWMEEVRALGLHKEIKILAGITPLKGVGGARYM
QKFVPGIDVPQDIVDRMAGVEKGPPSQAEGKKIAVEMIKEFTEIEGVAGVHIMAIEWEPA
VPEIVEAAGLLPRPAVA
>M1WGQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Claviceps purpurea (strain 20.1)|TrEMBL
MLIKDMLLEAEQNGQPSFSFEYFPPKTAQGVQNLYERIDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLDKVNDALQRAYKAGCTNILALRGDPPRAQEQ
WTATEDGFQYARDLVKHIRATYGAHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGASF
IVTQMFYDADNFIRWLRKVRERGITIPVLPGIMPIATYASFLRRAKHMQCKVPEAWMAAL
EPVKNDDVAVREIGTTLVAEMCRKLLANGIYHLHFYTMNLAQATRMVLDELNWAPCAERP
LKHALPWKQSKALGRRDEDVRPIFWRNRNRSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRNKWGEPTTVQEIADIFVRYLNQEIDSLPWSEAPLTSEADAIKDRLIA
LNKRGLLTINSQPAVDGVRSSHPVHGWGPSNGFVYQKAYLELLVPASIFTEVAKRLQTKP
TLTYYAVTKDGELHTNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
AHCFESNTASRVLLDKVMDEWYLINVVNNDFHENDTIFDLFEGLEVTELDTPTAS
>A0A538FM31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAPGPVELVCEVEPPTRPGLMHVRHQIGVLSKVASSFLIPDNHLGRATVSSVAVAHEVER
MGGRSIACVNARDRNLLGFRRDLLTAAAYGVDQFLLVYGDEPASGGRTGELTVRSMLDEL
RTFSATPAFEGGRPFRAGVTSRLRPLPPWKAEADFVFAQVSFSLDELLRWRDALDFDGPV
YAGVIVLASAPMARKLDSAIAEIAVPQEWVEAVERDPSAGVELACGLARDVMDSGAFAGV
HLIPGARYREVAARLEAGLRRP
>A0A538M7Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
TADLLGAWALGARNVFCLSGDPAHVGDHPDAAVVGDLTVGEVIGLARRMRDDGTTLANTE
LADPPRYLIGVADVPFAEPYDPSRLESKLDAGADFVTTQIVYDAERLAGWAEAMRPRGLF
ERAKVIIGVTPLRNAKQARFMDEKLPGVRVPSPTIAALEAAGEDAGAVGMDLTVQLVEAI
RTIPDIAGIHVMAMGHDAVTRDLVERTGLFPRPTV
>A0A523V4J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MQASLKPGLEEVLKQGKFAVTCEVGPPKGAETGEIEESVAYLKDVADGINVTDLQSSVMR
LGSLTTSSLLKEMGLDPIFQITCRDKNRLSIQSELLSAYVMGIRNVLALTADHTTMGDHP
DARPVFDLDSVQLLWTIKRLEEGYDLAGNELTEKPSFFKGAVVNPGADSEAAYELQILKL
KKKIEQGAQFIQTQAIFDAEVFKKFMDRMEKEKITIPILAGIILLKSDRMANFMNKNVAG
VFVPDPVIDRMKKTDNKVETCKEIASELIEDVKPYCAGVHIQALGWEKHVAPILEGIK
>A0A538AJP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MANRFVERLRDGPVIVADGGMGVLVSSTAPRLRCPEEANLRAPETVVKLHAGFIQAGADL
IETNTFGANRRKLAAHFLEDDVQAINSTAVKLARDAREMSGRDVFIGGSIGPLGELERIT
HDERAEIFAEQASILEGRGVDLFSVETFFDLEELETAIEAVRSVSSLPILAMLTFDEQAE
TLSGVSAREAVDRLRELNVDAVGANHGAGIQAALRALSAMKGDGVPLAAMPNIGLASIAG
NRIIYPHATPEYFAEFAAHARSLGARVIGGCCGTTPTEIAAIASAVKEEREPAAPLVFAE
REVVVKLAEEKRETELARKFREGEWVVSVQVDPPLGGSYAGMLEVAHTLKDSSKAHLIDI
NDNATARAAASALMLSVEIERGVGMETIPHLTTRDATIMGLESQLLGAHACGIRNVLAVT
GDPPEVGDYPGSRGVYEIDSIGLTQLMARLNQGEDYNGRAIDAATSFYIGVAVNPSADDL
DEELDRFQRKVEGGADFAMTQIVFDLEYLDRFLDRIGGEWPIPVLVGIFPVWSHQLALRL
HNEVPGIVVPDGVLDALRDAGPNANEVGMELGRTLLAEAREKADGAYVVAPFRRPLGILD
ALD
>A0A533RNS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSLSDAFGSGRFVVTSEVGPPKGTDVAEMLATAEMLRAHVDALNVTDNQAAVMRLCTLSA
CAHLATAGHEVVYQVTCRDRNRLALQSDLLGAASFGITNVLALTGDHTRVGDHPGAKAVF
DLESVQLLRVIQTLNAGADMADKALHGTPGFFAGAVVTPDSVPLAPQLARFEKKVAAGAR
YFQTQAVYDLASFERFMEVARRFDVKVLAGIVVLRSARMASFMNANLPGITVPERIVAEL
AASEDAAATGVEIAARFIRGARDMCDGVHIMAIGAEHLAPRVLAEAGLARKVPA
>A0A380P2Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weissella viridescens|TrEMBL
MTQVVMDNHRLYQFQQALKTAQVSMPLIIGVMPYVQRERVIKMIQLTQVTPSPVVQGLLT
QTDVNAFKSEGLALTIKQIVDLRKHGYSHIHLFCQNDIAVVSELFQGL
>A0A538LDD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARISDLLEGGRTFSIELWPPRSETAERRLETALAELQLLRPAFTSITYGAGGSTRERTH
DLVVRLQHQSSMTAMAHLTCAAHRREQLEDVLVRYRDAGVENILALHGDPPLDADSGLPD
GDLRYALDLVELARSVSPFCVAVAAHPEGHPQAPDRATDRRHTALKLEVADFAITQFFFH
LEDYLDLVESLSALGVDKPVIPGIMPITSVRTVTRMCELSGTEVPRSVTDRLEPVADQPD
EVRRIGVEVATELGQKLLAEGVPGLHFYTMNQAAATREIYNNLGLGPAV
>A0A537VLF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
FVLTQPFYSIDPLLALRETYEKVAGEPLTVPVIAGVLPLMMSRHAEFLHNEVPGIEIPEA
ARDRMRSAGDDDDRAWEEGAAMAIELIAALREEGVAGVYVMPQFGRYDRAAEVVEAARGP
ATM
>Q0A6D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1)|TrEMBL
MEQSQTMESQKQHPPVYSCEFFPPRTEQGVEKLRTTRERLARLNPAYFSVTFGAGGSTRD
RTYETVTEIQRSGLEAAPHISCIGSTRESIRELLHGYREQGIRRIVALRGDMPSGTRDVG
EFRYANELVAFIRAETGDHFHIEVACYPEFHPQARDAEADMDNFARKVEAGADAAITQYF
FNADAYFHFVGQAEKRGVTLPIVPGIMPIINFTQLARFSDACGAEIPRWLRKRLEAYGDD
KAAIQALGHEVVRDLCQRLLDGGAPGLHFYSMNQARPVERLWADLQLPR
>A0A1G7HSG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. cl6col|TrEMBL
MRDRMKNFREALHEQIIIGDGAMGTYLYQLGYPVGISYEILNVTDPDVIRNIHKQYVDAG
SGLLETNTFTANREKLYRHGKEHLVKDINRAAVRLAREAAGNQAYVIGALGSIRAGKREN
VHTNQVIRDYHEQMSAMLEEGVDGIMFETFYDLEEMRLALQVVRELDQDVPVICQFAVEE
SRRTKDGKSLLEAFRVLRDDGADVVGLNCHMGPNGVLRALEGVQGRIDLPLSAFPNAGLP
DYVDGRYNFVASAEYMAQSAVKFVQMGARIVGGCCGTTPEHVAAIVEALRDVEVPELPVQ
PVESIIIEEESESMLWHDGAACYDGCDHGHDAEESIVDMVRSRHTVIVELDPPRDLDVSK
FMKGAQVLKEAGVDALTLADNSLAVTRMSNLALGYMALDKVGIRPLVHIACRDRNLIGTQ
SHMMGLHALGIDHVLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNSGLAFSGKPLK
QKAKFVVGGAFNPNVKHLDKAIARLERKIEAGADYIMTQPVYDKELIVRIAEATKHLNVP
VFIGIMPLASGRNAEYLHNEVPGIQLSDEVRSRMSGLEGEAGRKEGVAIAKELLDVALTH
FKGIYFMTPFMFYEMTAELTQYVWEKAERQADPLYRLT
>A0A858UB95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYLAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGK
ARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQ
QILACVMPLTLGRANFMIKHKVAGIVITPHMLKVLAGEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVTTGKEFTPEIARFSR
QPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAKALLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKKT
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A6N6SZT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiaceae bacterium|TrEMBL
MENVKERRSRLVGDGDINVSFEFFPPKTDRMEEALWTSIRRLEPLRPRFVSVTYGAGGST
RERTHATVARLARETKLVPAAHLTCVQATKAEVDEVARDYRAAGVHHVVALRGDPPAGVG
TPYSPHLGGYANAAELVAGLKRIGDFDVSVAGYPEKHPDSPTVADDLDNLKAKVDAGASR
VITQFFFDNAHYVRFLEQARARGIWVPIIPGIVPIHNFKQVAGFAARCGATIPSWLARRF
DGLDADPQTTHLVAAAMAAEQVMDLVDQGIRQFHFYTLNRADLVYAICHLLGLRAEPAPE
KKVVNA
>A0A6S6U1L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Sulfurovum sp|TrEMBL
MFKEFCDFLCSDTDKFITVEVNPPHGASIDGLIDDIRKHNLHEKISGFSCTDNPLAKLKM
SGVLSAIKIQQEFGKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKFSDQP
EVKGVVERDSSLLLSIIYHLNNGVDYSNKVLTPRPKPIYPFAVANSYARDNKKLQKRMIK
KLNYGARAIITQPVYDLEGAKELLEIFDEARELSIRDTAKEAQLVLGQFPIVSTRTANFI
NDKVPGIHVPKEIIDDMNLAAMDGVEKEKEVGYNISKAIFDDIMTEHGKVHLMTHNRFDL
CAKLIG
>A0A7Y3JB35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MNLSHLSFEFFPPKTPEGAVKLRAARQRLYAHDPEFCSVTFGAGGSTQDGTLHAVKEIAE
EGVAAAPHLSCVGASRDSVRGLLQRYRAAGIRRIVALRGDLPSGYGLGGEFHHARDLVEC
IRAETGDWFHIEVAAYPEVHPQARSPQDDLRHFVDKMQAGANSAITQYFFNSDAYFRFAD
DVLAAGVGAPVVPGVMPITNASQLLRFSEVCGAEVPRWIRLRLLSFGDDRASILAFGREV
VADLCDQLVSGGAPGLHIYTLNQAEPTLGLLADLGMR
>A0A1F8MBK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_51_36|TrEMBL
MAKSFREILKTKDFVVTAECGPVKGSSVSKAVEHIELLKDKVDGLNVTDNQSSVMRYPSL
GVCLLIKEHGGEPILQVTCRDRNRLALQADLLFAHSRGIGNILCLTGDSIDVGDHKEAKQ
VFDLDSVQLIQLVHTMNSGKDMAGNELDGGIDFCIGTTATPSADPLEPQLIKVEKKLKAG
VSFIQTQAVYELDELRRFMEFVRNIDGKVKVLAGIVPVIGAKMAAYMNENVPGVFIPQRI
IDELAQAPKGTGVAKGIEIAARMIRQMKEEKICDGVHIMFIGREEKVPDILGAAGLL
>A0A2T0XBJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|beta proteobacterium MWH-P2sevCIIIb|TrEMBL
MSSRSDSVFSLEFFPPRDDAAQERLLAGAQKMLVMQPHYCSVTFGAGGSTKDGTLETVRT
LRGMGCEAAPHLSCIGASHSELRSLLHRYREEGIKRIVALRGDLPSGMGLNEGALRYASD
LVGFIRKETGDWFHIEVGAYPEMHPQASGPERDLDHFVRKVEAGADSAITQYFFNADAYF
DFVDRALARGIDIPIVPGIMPITNHNQLMRFSDMCGAEVPRWIRLRLAEMGDDKASIKAF
GAEVVTQLCQTLLENDVPGLHFYTLNNADATLAIWRGLTQ
>A0A2H0ISK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagales bacterium CG12_big_fil_rev_8_21_14_0_65_40_12|TrEMBL
MKVTQHIKRAKGKTLFSFEILPPRKGENVNGIFEAIDPLMEFNPPFIDVTYHREEYIYKQ
RENGLLEKVTTRKRPGTVGICSAIMNKYGVDAVPHIICGGFSKEETENALIDLDFLGIDN
VLVLRGDAIKSEGKFVPDPHGHAYAVELMQQVLDLNKGKYLHEEIESGATNFSIGVAGYP
EKHFEAPSLKSDMKYLKQKIDLGAEYVVTQMFFDNKKYFDFVDKCREAGINVPIIPGLKP
ITTLNHSTILPSIFHVDLPDDLVDALDKCKNNNDVKEVGVEWCIQQSKELMAAKVPCLHY
YTMSKSSVIKRIASELF
>A0A3S0NFF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHKELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDYFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A2T6BL18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoreibacter ponti|TrEMBL
MPAVSFEFFPPKTLEASFRLWDTIQTLAPLGPDFVSVTYGAGGTTRELTHEAVAALTKTT
DLKVAAHLTCVNATRAETLQIAREYTAAGVTDIVALRGDAPKGQELRAAPDGFISSIDLI
AALKAETTATIRVGAYPDSHPEAASMDANIKYLKEKFDAGADAAITQFFFEADTFFRFRD
ACEKAGIDKPILPGILPIEDWSKARSFAKRCGTTVPAWLDEAFEAAIRDDRHDLLAQAVI
TELCSDLVEGGVNHLHFYTLNRPELTRDICAALGITPKMELAQVA
>W7UU54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus flavefaciens 007c|TrEMBL
MYIKELFKNKTVFSFEVFPPKKTSPVEVIYDTLEELQGLSPDFISVTFGAGGSGNSRYAL
EIASKINESGIIPMLHLPCINFTKAEIDAALDEAKSRGIENILALRGDINPEIEPVNDFR
YASDLISYIKTNGDFDIAAACYPECHPDAENLVEDITNLRKKVDAGADHLITQLFFDNDN
FYSFREKAAIAGINVPIEAGIMPVVNKKQIERMVTTCGASLPAKFVRIMTKYEHNPEALR
DAGIAYAVNQIIDLVASGVDGIHLYTMNNPYVARKISEAVSGVIGV
>A0A432QVD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurobacterium sp|TrEMBL
MSFSEKLRNGKFIITAEVAPPRGTDWKSVIEGIEPLKGKVDAFNVTDNQRSMVRMSSLAM
SKLLLNSGFEPIFQLTCRDRNRIALQSELLGAAALGIRNICLMTGDFTTLGDQPDAKPVF
DVDSVQLIELAKKLESGKLLNGKEIKGSVEFTVGAVYNPFAGPKTLQEWKLRKKVEAGAE
FIQTQPVYDIRVAEEVNDLIGALGAVPIIGLLPVKSLKMANFMKKLNPTSVPDKLIEGLE
KANDPAQYGWDYVIDIAHAIAEFGRGIHFMLVGKTAELAAFIDYLRNDSPYNHKF
>D6Z1V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurivibrio alkaliphilus (strain DSM 19089 / UNIQEM U267 / AHT2)|TrEMBL
METAMKAGSRLERVLKSGAFAVTGELGPPKSADPEVVRKKARLLKGRVDAVNITDCQTAI
VRMSSIGAGLLVQAEGVEPVIQMTCRDRNRLAMQSDILGASALGLKNLLCLTGDHQKFGN
HPGAKGVFDMDSIQLLGMMRDMRDEQKFQCGEAIKAHEPRLFLGCAANPFAGPSEAARAA
RLGKKVSNGADFVQTQIIYNMERFAAFMAAVRDLGLDEKVYILAGVTPPRSVGMARYMKN
FVPGLDVPDEVIKRLQGAKDKEEEGINICVDIIQQCREIKGVAGVHVMAIEWEEAVAEIV
QRAGLEQRPEVPEAEVASTIAAQPKAVPETVTVAAEAAPAGAGEAELAAARLEAEKIVAA
AREEASRLRAQAPAAVATDTSDQIHAQSAEAGEDEMNERERQMALESVRHGLAALKKAFN
LSDDQFDALAQFAGAEAILKREPAAAPPVPAAPAAAAPAAPAASAAPAADQAAEAKKAEE
ARKAEEAKKAAEAKAAEEAKKAAEAKAQAEAKAAEEAKKAAEAKAQAEAKAAEEAKKAEA
AKAASKPAPAPAEAPAAPAKSAAPADLAVGELAVEESTLAQRGGKVPAANYTQDYSGAIR
EVALGNGDKIVTVGGTNSLPFHLFEGKLEHPPLIAMDILDIKPEEWPASLSRHFADVMDN
PVAWAQKCVNDYQAEAICISLVGTDPNGMNRPASEAAKIAAQVVDAVDVPIIVWGCGNAE
KDTETLREVTSIIGDKKVCLAPLDDSNYRSLGATAMAFGHPMVASSPIDVNLAKQLNILL
ENLGVSLNSVLIDPSIGALGYGIEYTYSVMERIRLAALTQKDEKLQLPFICNLGREVWKA
KECRLPSDEMLGDAENRGVLMEAITASCMLMAGGETLIMRHPRAIALTKSLIKGLMG
>A0A1Q7XE14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon 13_1_20CM_2_39_20|TrEMBL
MTVTYELNPPKVIQDTVLSHQQLQESVNKLKTKALEVSKVCNSIHVTDSVLGIPRISPIT
IGVFIRNSNDGIELSASVRVRDRNLTSLTQTICDAILLDLNAVLILKGDPPPAGPKDSKL
VPSEVVKQFNEQGFGKKIDLFLSLPSNPNFEKIHKKIEAQPKGFVTQVISSFDQIIKIVD
KLKPQGFRIIPCILLPSEKNLQSAKRLNLDWSNYSNDVVGFIKDAHKISGNVLISSPNDF
KRALEILKKLT
>D6Z060|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurivibrio alkaliphilus (strain DSM 19089 / UNIQEM U267 / AHT2)|TrEMBL
MTLSPFFRALSDPDNFTLTLELVPGRSGRGTGHDRALAVARQAVADGRLTAVSITENAGG
QVALSPEVLGVEICALGLEVIVHLSCKDKNRNQMESQLFAWDRLGISDLLVITGDYPKPG
YRGLSKPVFDLDSVQALDLIGVMNRGGWPSGGEKARPNPLLQTTGFVKGVALSPFKHSEP
ELVMQYVKLRRKLAAGADYIITQIGYDARKFQEVLLFLERQGQGRVPVLGNVFIPSLKVA
ELMYRGEIPGCVIPEKLYTTMQQEARSPDRGKKARLMRAAALLAVLRGLGYAGAHIGGPG
LTYDDIALVLDRAEELAADWRALLPELAFWPEDSCFLFRRDPETGLNLPEEEPLTEPGGE
KWSYYLSHLAHEAAFVPRGPFYRPMKRLCLAWDDSRLSRALIHFEHLLKFLAFGCKNCGD
CTLVELAYLCPQAACAKYILNGPCGGSRDGWCEVYPGRRRCIYVRAYQRLKSVGRQAEMK
DDLVPPRDWSLNNTSSWVNYFRGLDHQGGPDQD
>A0A384IAB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. AC1-42W|TrEMBL
MDLVMDRPTFSFEFFPPRTAQGERTLWQAIRRLEPLGPDFVSVTYGAGGSSRDRTIDVTK
RLVTETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPKGEWTAHPDG
FHHAYQLVELVRSLGDFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFDV
EDYLRLRDRVAAAGCTTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAQHRPDI
AYEIGVAHATLMADRLLAEGAPGLHYITLNKSTATLDIHRNVMSTRSLHAS
>A0A4Y6R305|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. NIBRBAC000502772|TrEMBL
MSPPSLIETHPNLTETAPVALSYELFPPRSPAAAESLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPEELAEIIGDLLDTGVRGILALRGDQPKD
GAPLAAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPTEAHDVEVLL
AKQRSGADFAITQVFFHTEQYANLISRARRAGVTIPIIPGVMPLTSLRRVTRLGELTGVE
PAPELLARLAAADTDSERLRIGVRATVDLANAALEAGAPGIHIYTFNEHQSALEVLDKLA
LPRQSRSAGRRSATLRRQLAS
>A0A366GKW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter pelagius|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQTVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LSLHKQGISTAPHLSCVGGTREEIGELLDVYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIERLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCERLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A4S4LJ72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phellinidium pouzarii|TrEMBL
MSELGPIAVSVTWGAGGSTRERSLDLAEIAQTEYGIDTLLHLTCTNMEQGLVDGALRKAK
ELGIENILALRGDPPRGEEYWIPTDPRFTHAIDLVKYIKSSPEFSSSFCVGVAAYSDGHD
TDVDEDTELNCLKAKVDAGAEFIITQLFLRWITVPVIPGIMPLQSYASFLRLTKLCGTKV
PPELHLQLEPLRHDDQKMKDFGVTLAADMIKRLIDDGDVKGVHFCTLNLERSVRKVLENL
DWAGGSPRTSNKLIIDSADTNARESAPNDLTIRPADANQTATDKLATKPLPEIQAQGKGE
INNASTWDEFPNGRFASEMVWEFRSVDETQYLANKERQLNDKGNLKRTEAISRWGSPKSV
TDLTELFLSHLHSVITSTPFSPSPLSPESLLILSHLERLTRRGWWTVFSQPAVDGVDSAD
EVFGWGPANGYVFQKGFVEFFAEKEDVDRLEEKIRSKGDGWVDFFAANEKVGRVDG
>A0A377XII8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae|TrEMBL
MSFFHANQREALNQCLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDLISLSPRIRKCIRRRKARRRIY
>A0A1T5CX33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides chartae|TrEMBL
MKVIDLIQGSGKTAFSFEILPPLKGNSIQKVYNVIDKLREFDPKYINITSHHSEYIYKTL
PDGKMEKVNIRKRPGSVAIASAIQNKYNITAVPHIICKGFTKEETEYALIDLNFLGVYDL
LLLRGDIKTLEAADANSKLYHNHATDLQEQINNFNKGIAVDGSTFEANETPFSYGMACYP
EKHEEAPNMDSDIHYLKQKVANGADYLVTQMFFDNQKYYDFVERCRAEGIQVPIIPGIKP
VVFKNQLTVLPKIFRSDIPEPFASELRKCNTDEEAREVGVEWCINQCKDLVAHGVPSLHF
YTMMATDSVYRVAKEIY
>A0A5C6EJL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubripirellula tenax|TrEMBL
MSLLSHYNESRPAISFELFPPKTEEGMEVLCDNVRQLCEFKPSYFTCTYGAGGSTRGTTL
SVLQRVREITNLPVASHLTCVGSTVAELESYLAEAVAQGVDYIVALRGDPPKGTDKFVAV
EGGLNYANELVEVIQGKFSNLGIAVAGYPEVHQEAPDAKTDLENLKRKVDAGADIVVTQL
FYDNIDYFRFRDRCVAAGINVPIVPGILPVTNFKQAQRIASMCKAGIPYDLEKAMNATDD
PQSQFEIGVEHARQQTINLIENGVPGIHYYVLNKSDAAKALLDGIQMVG
>K5X1L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC 10392)|TrEMBL
MKISQKIQQQSKENKLWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
ELTSQMVKTCQSLIGIETCMHLTCTNMPIEKVDIALREAKASGCRNVLALRGDPPAGKEE
WEAIEGGFVHGIDLVRHIRKLYGDYFDIAIAGFPQQMLLPPEELEQEMMWLKEKIDAGCS
FIFTQMFYDVEIFIKWVHCVREHGITIPIIPGIAPIQTWNGFMRATSLAKTIIPQSFMDV
LEPIKNNDEQVRKLGIKLVADMCRRILAEPLGIQGLHFYTMNLEKGTKMLLEELNLVPRV
ETIKPLPWRQSLTPSRRAETIRPIFWANRAQSYVSRTENWDEYPNGRFGDSRSPAYGELD
GYGVSLKHTKDDALKLWGEPKTFADVTSLFTRFCTGELTALPWSDQKLETETSVIAKQLA
QMNDLGFLTINSQPAVNGARSDDKVFGWGPANGYVYQKAYLEFFVTPSLLDLLIPHIERD
SNITYYVINKAGDLRTNTHSDGPNAVTWGVFAGKEIIQPTIVEAISFMAWKDEAFELGKQ
WAALYEADSPSHKLIHELMETCLLVNVVHNDFHDTEAIFKPFLKAGAEFFAKTKPLTNGH
>A0A2Z5BL52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. PM5|TrEMBL
MSVMTPTPAALASRVAGCPKSMAYGPCGGVNADGTCEVHPTPCVFLARELPVRWTGAAAR
ATDPEAGSGDPSTASTLAGRELVAIAARRPLVFTGFPVRALRADAVGATAEALLGSVDAV
LSGDAGRSRVQFPPSYRAALIGATGLRLWMGFNTRDRNRTALERELLSLRALGVAGVHCV
TGDHTQTGDRPDARPVFDLESTTTLPRAAALGLLTSFAESPAAPPIAERGARVAEKQRAG
GRMCLTQYAGDAEEVAAFVALCRAAGSDVPVLPGVPLVVDREGAELLASFHAAKLPSGFI
DRLFAARDVRAEGIRLAVAYGQALIATGEVGGVVIAGGARPGDEAAYAADLATVARELGG
GS
>A0A2Z5BJV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. PM5|TrEMBL
MTASLRLHEATRRCPKRMVHGPCGGVTVDGGCEVPGIRCSFVDDAAVLRHLEFSTAEVDA
PVAARDSGDALPVLPRGEASTAFAALVEAGAVITADLPVRSVDPAVITEAGVRLRELTAV
IAGEPPGLREALSPTHKALLLAAAGSRVVAGLTCRDRNRVAIEGELAALADLGVSGVLAV
TGDHPASTALPQAQPVFDLDATRLAALARRAGLFVAVAEQPSAPPVDYRPTRLARKAHAG
AELGILNLCGDLAEIRRFTAALATTATPVPVLVSVPVLTSAATTRRLAALPGVGLPDELV
RAVAGADDPVESGIAAAVAWAHRALAIPGVVGVHLSAIAAGATEPPDRADAAELAAVDAL
ASAAARLRAVIAADAIVAETAGDA
>A0A0S9R412|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. Leaf111|TrEMBL
MPSASHHRASRDSYRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVKETSLQPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPQDGIG
TAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEASSLDADIDALKAKVDAGADQ
AITQFFFENDIYLRYVDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLDNDVETRRLVAAAVAAEQVLDLVDHGVNDFHFYSMNRSDLVYAICHVLGLRAQAPKV
AAKAA
>A0A1M7GH23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium pectinovorum|TrEMBL
MKVTEHIENAKGNTLFSFELIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKVGGNSFAIDLVRQINDLNCGKYLHEVMDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFTFVEKAREMGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQIF
>A0A8H0BXV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus mirabilis|TrEMBL
YGANSGERDRTHAIIKDIKERTGLEAAPHLTCIDACREELQHIAQDYWQSGIRHIVALRG
DLPDNSQKPDMYAVDLVHLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKKKVDAGANR
AITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMF
DGLDNDPETRALVGASIAIDMVKILSREGVKDFHFYTLNRSELAYAICHTLGVRPQLAKV
>A0A7L5AXA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 604F|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRAAADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A7G5E8B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium multivorum|TrEMBL
MKIIDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPSDGGHAFATDLLEQVTDMNKGKYLHEDIITSEKTDFCIGVAGY
PEKHFESPNFNTDFKYLKQKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVSACKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLA
>A0A445MVG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MKYVSRLKSVLEKGGFAVTSECGPPKGADPQAILKKAELLRGKVDSVNVTDNQTGVVRLS
SMAAGVLIRQAGLDPVLQMVVRDRNRIALQSDILGASAIGIRNVLCLSGDHQSFGNQPDA
VGVFDLDSIQFVQVVKNMRDERVVIGGDTLGQPPDMFIGAAANPFADPLDFRVVRLAKKI
NAGADFIQTQCIFNFERFDKWLSAARDRGLTEKACILGGVTPLKSAGMARYMKTKVSGID
VPDELIRRMECVSKDRQREEGIRICVETIERLKQTPGIRGVHIMAIEWEEAVGEIAQRAG
LLPRPVPDDQ
>A0A2A3JN59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ag82_O1-15|TrEMBL
MDSVSTASASAVAPLLDDFSLEMTGKDVPKLEEARGTIPRGTRINVTFLGNEDLGMRLAA
ARAVKRLGFVPVPHISARRLSSRAALEEFLAALEADGLADNVFVVGGDPVEPHGPYDDAL
ALIRSGLLQKHGVRHVGVSGYPEGHPAIADPVLWSAMEHKSAALEEHGLPGAVITQFGFD
VDAVLAWVEAVRARGIGLPVRIGVPGPAGIRRLMTYAARFGVGTSTSIAKKYGFSLTNLM
GTAGPDRFIRALANGYDARRHGELKLHFYTFGGLKTTSEWVADFRDKEN
>A0A1G9G1U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maridesulfovibrio ferrireducens|TrEMBL
MNVASSIKESNQFFSFEFFPPKEKQAWGNFTEKAERLANLKPLFASVTYGAGGSSHDNSL
DVCGVIKKEMGVDILAHLTCVGASETSIDDFVGRLNDAGVSDILALGGDGRKDDVNNESR
FFHAADLVEYVDDKFSDVGIAVAGYPGGHPDASTIAQDIRYHCDKLSRGSDFTITQLFFD
NRQYFDYVSRLEISGFEQPVIPGVLPIQSLGSLRRIMGLCGASIPGDLYCGVEKAFEAGG
DKAVMEFGFNFAQQQIAGLLDGGAPGVHIYTLNRASMCERLIGSLKSDGYFI
>A0A2N1NVI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus irregularis|TrEMBL
MKITDKINNNLETSQPFYSFEYFPPKTDEGLNNLYDRLKRMSHLDPLFASFTWGAGGSTI
DRTTEMCATAQSLYGLESCMHLTCTNVVRGTIEKAMKEAKSAGIQNILALRGDPPRGQEY
WTSCDSDFTHAIDLVRFIRKEYGDYFCIGVAGYPEGNPDSENKEQDLKFLKEKVDAGADF
IITQLFYDVNTFVEWRDECRKNGINVPIIPGIMPIQGYNSFRRITNLCKIHIPAEILNVL
EPIKHDDQAVKDYGVTLAVSMISKLRNEHNTRGFHLCTMNLEKSVRLILEILGFVQTEEE
RNLRRLSRRRSSAGFGPNDIIRQEPDGSLPTAKPVIWKERSVDYLGRPEDWDNFPNGRWG
DARSPAFGELDGYGVSLRIPPEQALGYWQRPTTLDDLKQVFKSYILGEIPALPWYEEPLY
AETEAIRSKLVHLNELGFLTVSSQPAVNGARSDDPIYGWGPRGGYVYQKAFVEFFVSPEN
FEELVEKIKGNPWVTYCASNRNGDFRCNTKDDSPSAVTWGVFPGKEIVQPTIIAKVSFNT
WKDEAYALWTEWEHLYPKDSPSQRLLKDIGDNWWLVNLVYHNYVNSEEIWEIFFKL
>A0A1G1LGS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica bacterium RIFCSPLOWO2_12_FULL_50_11|TrEMBL
MTLREKLSKGQFVFTAEIGPPKGVDVTRTLNEVRAMGNHIDAINVTDLQGGLMKMSSLAL
SHLLVDEGREPIFQLTASARNRLAIQSELLSAYALGIRNVLLLGGDPPSVGDHKDAKPVY
DLDTMGMFQAVKALKSGTDLAGHSLEGAPDLFVAGAANPGAKDLEVECQKIEKKVEHGCE
FFQTQAVYEAASFETFRRMTKNVRAPFLVGIILVKSAKMARYMNEHIPGIHVPDEIIQEV
DDARDKEKKAVEIAVRLIRELKPMAEGVHLMPIGWGHLLPEVIEQAKQEAKV
>A0A3P6GPS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica oleracea|TrEMBL
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNAICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEADGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPVVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAFGIHFATEMCKKILAHGISTLHIYTLNMDKSAIGILMNL
GLIDESKITRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYGTLSDYQFMRPRARDKKLQQEWVVPLKGIEDVQEKFKELCLGSLKSSPWSELDGLQPE
TKIINEKLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TFMEKSKAFPSITYMAVNKAGNWVSNVGEADVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPCRKLLEEVKNSYFLVSLVDNDYINGDIFSIFA
>K7HSL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis japonica|TrEMBL
MVVFSQNGIETEENGIVDEKPTQEAQRSWSPKHYELLHERIERLIEEKQQFFSLEFFPPR
FVNGVPNFLERVERLSEGGSVFVDMTWHMGSDPANVDKVTSSSSIAASMLDYCGVDTMLH
MTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPGTELQDTHQFRALDIIRWIREEYGD
YFSIACAGYPLGHPQAPSYKADLQYLKAKCDAGANFVITQLFYEAETFENFVRDCREIGI
TKPIIPGIMPIMAYESTIRIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTEKCIEMCKR
LLGNGSAPSVHMYTMNREGSIREILKALGLWKLEGDRVFPWKNRSQHPIRCLESVRPIYW
SFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTVRNPDDRLGMFGAAIES
FEDVKQVFINYITQTPNSSGIKVTVLPWTEAETGVQPETALIRDQLVWCNENGILTVNSQ
PSVNGAPSTDPLVVLHDRRMSEKLIQVIERDFPIRVNYHAIDKDSTFDKTNSEETTPIAV
TWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQ
>A0A1J4VYS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG1_02_49_16|TrEMBL
MNILEIYHKKKFVITAELGPPKGTNLRPFFRQAGYLKGRVDAVNVTDQQSALMKLGSLAC
CHLLKDFGLEPVMQITCRDKNRLALQSEILSGSVLGIRNVLVLTGDPIAIGDHPQAKCVF
DLDAAELMAVIKTMESGVDMTGHPLDGVPQFSIGAALNPCAEDMEIEISKIRNKIKKGAD
FFQTQGVFDVERFKKFADRYQKEGFRAPLLAGIILLKSPKMANFMNEKIPGVHIPGALIA
RLEKAEDPKARSVAMACETIQSIRSCIQGVHLMAIGWEELIPEIVSKTS
>A1K2Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azoarcus sp. (strain BH72)|TrEMBL
MHKTELSIEFFPPQTAEGAEKLRAVQARLAELKPTFFSVTYGAGGSTRERTFATVKEIAA
SGSEAAPHLSCIGSTRDSIRAILAEYADAGVKRIVALRGDLPSGVVDPGEFRYANELVEF
IRAETGSRFRIEVAAYPEWHPQAKTPADDLAAFKRKMDAGADSAITQYFYNLDAYLHFVD
AVRKLGIDKPVVPGIMPIGSFSKLARFSDACGAEIPRWMRRKFESYGDDADAIRAFGLDV
VTELCEKLLAAGVPGLHFYSMNQSALTTEICKRLGLA
>A0A417QUD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. OM07-19|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSVGMVRFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A3B7D0T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. dhg|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSNEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKSETGLVAAPHLTCIDATREELIEIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVVAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAV
>A0A8J6YHX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Quinella sp. 1Q5|TrEMBL
MGRIAVEIIPRDEASLQADIDVIKKYPQVDCVNIPDLMSFDLRPWQAAKVTQPALPTIPH
VRAMDIDLSKPLPMRDDFIKFGIKEVLIIVGDPPKDLTRTVYPTETIDVIRKFREELPDV
KVYAGIDQYRSSIRDELYRVERKAQAGAVGFFTQPFFDMRFLEMYADLLDGHEVYWGVSP
VFSNRSKGYWERKDKAVFPNDFKPTMDWNIDFAKRVIEFVKTSSGGLYFMPITIDIADLL
PRVFD
>A0A091AML7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuricurvum sp. MLSB|TrEMBL
MFGTFIEKLRSGTYITLETTPSRSAAFAPTIDKIEALGLHTLVDGFSTTDNPLAKLKYNA
LFAAVALQNRFGLPVLATMSMRDRNRIALQSDLLGANEADVRAILALTGDSAHYSDQPHA
KGVFEGNSKLLLDIISTFNRGVDLADQKLIVPPRPIYPFAVIDSYAKNSVALEKKMAKKV
SHGAIGIISQPVYDLDNARKLLEMMERANAEHNAECTLILGFFPITKLRTARFLDENVPG
IHVPDRWVEALEAASGIGPEEEYRVGFELSKNLFEELKA
>A0A804RV78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zea mays|TrEMBL
MAGRRSRSSTSLPRRRRGVENLFERMDRMVAHGPSFCDITWGAGGSTADLTLEIANRMQN
MVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDKFVQVEGGFACAL
DLVQHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLKRKVDAGADLIVT
QLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPSEITAALDPI
KDNEEAVRQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIGILMNLGLIEESKVSRPL
PWRPATNVFRVKEDVRPIFWANRPKSYL
>A0A1D6L978|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zea mays|TrEMBL
MKVIEKILEAAGDGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIGILMNL
GLIEESKVSRPLPWRPATNVFRVKEDVRPIFWANRPKSYLKRTLGWDQYPHGRWGDSRNP
SYGALTDHQFTRPRGRGKKLQEEWAVPLKSVEDISERFTNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVNINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLD
QLIEKIKAFPSLTYIAVNKDGETFSNISPNAVNAVTWGVFPGKEIIQPTVVDHASFMVWK
DEAFEIWTRGWGCMFPEGDSSRELLEKIPWLLTFRFRRPTTWSASLTTTTSRGTCLLPSR
SDYALMVCIVVWLDPTIFLHPRLQV
>A0A2M9TYG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Advenella sp. S44|TrEMBL
MSSFSDEAFSLEFFPPRDQVSRERLVGTAKQLMAMHPRYVSVTFGAGGSTRDGTAETVSL
FSQLGCEAAPHLSCIGASRESLVQLLDQYKAKGIRRIVALRGDLPSGMGGNDSDFRYASE
LVKLIREHSGDWFHVEVAAYPEMHPQADSPEQDLDNFVTKVNEGANSAITQYFFNADAYF
DFADRAVQRGVSIPIVPGIMPITNHTQLLRFSQTCGAEVPRWIRLRLAQFGDDKASIRAF
GTEVITQLCQRLIDGGVPGIHFYTLNNAEATLSVWKNLRY
>A0A0D6AHW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geminocystis sp. NIES-3708|TrEMBL
MNHFQKAIANKEFLITAEVTPPKGGNPQRMLEVAELLKNRVHAVNITDGSRAVLRMSSIA
ACYLLLQRGIEPICQVTGRDRNAIALQADLMGAYALGIRNILALTGDPLKAGDHPKSKAV
FELESVRLLQLIEQLNKGFDINNKPLTDGNLDLFAGAAVDPQSNSWSGLQRRFEAKLLAG
AKFFQSQLITDFDKLDLFMNQVAIGCDRPILAGIFLLKSAKNALFINKNVPGVNIPETII
KRLEKAEKPLEEGIKIAAEQIKLAKNICQGVHLMAVKKEDLIPEILDLAQIKAISNS
>E3HDJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ilyobacter polytropus (strain ATCC 51220 / DSM 2926 / LMG 16218 / CuHBu1)|TrEMBL
MFIKDIYESKKPVISFEIFPPNERYPVEKVYDTIDELVKLSPDFISVTYGAGGTTRGRTV
EIASRIKKVNNVEVLAHLTCIGADKVEIDGILDELKENGINNVLALRGDYPNDGSIPEGD
FKYAHQLVKQIKERGGFSIGGAFYPEGHQESNDLMDLFHLKRKAEEGTDFLISQIFFDNS
YFYDFKEKAKKLEIDVPLVAGIMPVTDARQIKRITALCGSSIPPKFQRILDRYENNPEAL
KDAGIAYAVEQIVDLISSGVDGIHLYTMNKVDTTQKIMDAIANLRIAL
>A0A502CGM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter glycinis|TrEMBL
MPAISFEFFPPKTDEQRTQLDRAAQVLKAHQPDYASVTFGAGGSTLSYTGDTVARLHTHH
GLHVAPHLSCVGGTRAELADLLDGYRAAGYRRIVALRGDMPSGMATAGDFRYAAELVQFI
REHSGDHFHIEVAAYPETHPQADDALRDLQHFKAKVDAGANGAITQYFFNPDAYFRFVDD
VRKLGVNVPIVPGIMPISNYSQLKRFSDMCGAEIPRWIAKRMQAHGDDAESVRALGAEVV
AQMCRRLLDGGAPGLHFYTLNRARATQLVLQQLS
>A0A2E3PVC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MPSTDKFRRFELGSGADVSVSFEFFPPKTEKMEASLWRAVERLQPLSPNFVSVTYGAGGS
TRERTHRTVERILRETDLSPAAHLTCVGSSREEVDAIVRDYQALGVKHIVALRGDPMEGI
GAIYKPQPDGYAYSCDLVEGIRRIGDFEVSVSAYPERHPESPDWATEIDNLKRKVDAGAT
RAITQYFFDNDLFETFMEKVRAAGIDIPIVPGILPIVNFETTMVFSAKCGTSIPDWLVRR
FAGLDQDVETRKLVASAVACEQVLDLVDRGVSDFHFYTMNRAELTYAICHTLGLRPAPEE
KQAA
>A0A2N1WFQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium HGW-Gammaproteobacteria-9|TrEMBL
MSTSPRPSISFEFFPTKTDAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDTKAELRELLNIYKDAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEVAAYPEMHPQARNFEDDLANFVRKAKAGANSAITQYFFNADCY
FYFVERVRKLGVDTPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCEKLLAGDAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A6L5GUN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pseudoramibacter fermentans|TrEMBL
MKLSEQFKVDRPMLSFEVFPPKTEARFEPIMSAVEEIAKLDPAYMSVTYGAGGGRSQYTV
DIAKSIKAMNVTPLAHLTCVSSDKTTIQTQLTALKAAGIENILALRGDLPKDYVPGEYRH
ASELIDEIHRFDGEFCIGGACYPEGHPESARQKDDIQHLKEKVDCGCEFLTTQMFFDNDL
FYNFMYKIREAGINVPIIAGIMPVTNAAQISRIVDLSGAFMPQSFLNIVDHFRDDPASIY
EAGIAYATEQIVDLFANGINHVHVYSMNKPDVAADIQNNLKSILDK
>A0A6N3S6C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella pertussis STO1-CHOC-0019|TrEMBL
MTQSTAPAFSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRT
LRNLGCDAAPHLSCIGATRDQLRDILAAYREQGVRRLVALRGDLPSGMGGDAGELRYASD
LVAFIRQETGDWFHIEVAAYPEMHPQAESPSADLAHFVNKVQAGADAAITQYFFNPDAYF
DFVERAQAKGVAIPIVPGIMPITNHTQLVRFSEMCGAEIPRWIRLRLAEYGDDKASIRAF
GLDVVSELCQTLLENGAPGVHFYTLNHAEATLGIWKALNA
>A0A0H2UP04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A7S4V191|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Guillardia theta|TrEMBL
MESGKRAIETLVAAKAVCSLDVQMHMSCTGITKKMADDLLVEAMDADIRSILVLRGDPAP
GKSDWEPVADGFKNASELVSYIRHKYGDFFSLSVAGHPGKHPASSSKEEDLEHLKQKVGC
GADFIITQMTFKASEYQEFVGSCRRVGIDCPIIPGVLMIPPSLEKLRAVCNHCSVEVPED
LVELLETCGSDKEKVREAGRVYMQRVCSEMLSSGAPGLYMYTLNLEKSAQEIVTNLNLKV
LDAGMSDSAVRPLPFPRPREKETVRPIFWASNAISYLTRTRNWSADFPSQWGQVNNEKSK
AGDHSFVYDPLPSGDEDNILYSHHSIVGRRLGSMAERRNMWGESPSTEEDVFDVFERFVR
GFVPRLPWCDRLEKETLASGILKPLATLNHYGYLTINSQPRVNGAPSEDEQFGWGPRGGH
VYQKAYLEFFCSPGNLDRLLEALGSHPSISLEAFNVNGGRRCVWTDSLGQRNKTDEANVV
RCSPSATLLSPSPLLIRQNL
>A0A0E1NMU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pestis bv. Antiqua (strain Antiqua)|TrEMBL
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIAIDYWNSGIRHIVALRGD
LPPNSGKPEMYACDLVGLLKDVGDFDISVAAYPEIHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFD
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A2I6BPH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSEEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNHADIAERIWNATKSVFDAANARTQTTIKHRS
>A0A355VFJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia sp|TrEMBL
MHLRERLQSGAGPSLSFEFFPPKNEQAASALYQTIRELEPYRPSFVSVTYGAGGSTRELT
REVVLRIQHESRIPTVPHLTCVGHSREEVWNILD
>A0A318V354|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinomonas alcarazii|TrEMBL
MKSELATKFQDPTRGIYFIGTTPPKSSLEEEQLAQVSQKLLERLDNIDIDGLVVYDIQDE
TSRIDKPRPFPFMETHDPRAWSKRLHQQSGKPVITYKSVSSRSSEEFSGWLSEAWEQYGI
RDLVLVGSPSSSGDIKLPLPQAYETLKASEHSFNLGGVTIAERHAKKGDEHLRLSKKTEA
GCEFFISQAVYNHQATADLISRYARTCKEKGEAPKRIILTFTPCGSAKTLEFMEWLGISV
PEATKHRILDAEAPLDESIKICRNALEQIIEIALPLGVPLGLNIESLTNRKEEIDASIQL
YKLLKATLDLKLAEQSLIK
>A0A4R2QQL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tamaricihabitans halophyticus|TrEMBL
MNTQTKQLQQYLATARFEVLPLRGVLDKVADLPPGTTVTVTSSPAKGIEATLATAAALRE
RGFAAVPHVAARLVADRRHLTDLLDRMAETGLSEMFVVAGDSPEPAGEFADSLALLRGLA
ELGRKPDRVGITGYPERHALISDGATIAAMSAKAPYADYIASQICFDPHTIANWVKSVRA
RGVRLPIHLGIPGVVDATKLLRISMKIGLGDSMRFLRKQHGVVGKLLTRFTPEDLCYQLA
PYLVDSEYGIAGWHFFTFNEVRKTDQFRTELATRLHEVPA
>A0A2A5LXV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. ANT_B65|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQVVRDQLAGVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTREEISELLDLYKENGINRIVALRGDMPSGMGASGEMRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVEAGANSAITQYFFNPESY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGSEIPRWIRKQLEAYGDDSVSIRK
FGEEVITRMCEKLLEAGAPGLHFYTLNQAEPSISIWKNLGISEREKIAF
>A0A7I7AH50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella planticola|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAEDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A3P4B8G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pigmentiphaga humi|TrEMBL
MPALSTGNQVSMDSRTARPDLDAIKRLAAVATIETSTREESEIRIQARRVAPGSDVYIPW
LPDSSWRDIVAVAAELRACGVNPVPHVAARRLLSREDAQQYLSALRGQAGVTRALLIGGE
HSAKRMGFAHSIELLESGLIETHGIRSLGFAGHPEGHPAVASEVMDAALQRKIAYADEHD
LEPFIVTQFAFDHRSVLSWLEHVRAIGIRAPVRLGVTGPASVRTLLRYALRCGIGTSLKT
VAARGPALMRLIEKGGAEDVVRAVAPRAAELGVIGLHLFPFGGFELSAGWIAKVAAEGL
>A0A0L7BQE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium breve MCC 1340|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGSHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQAVGEFNHASDLV
SYIRSVKPDLKVFGACYPEGHYQADTIDQDIENLKVKVDAGTTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A346NSR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinimonas sediminis|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPNSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRINQQTGIAAAPHLTCVDASKAELQQIAEDYWNSGIRRIVALRGDLP
AGVDKTDMYASDLVALLKDVADFDISVAAYPEKHPEAANAQSDLLNLKRKAEAGASEAIS
QFFFDTSTFLRFRDRTAAAGIDIDLVPGILPVTNYQTLLKFAGFTNVHVPGWMHKMFDGL
DKDDQTTRNLLGASIAMEQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRGNG
>I2BEC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shimwellia blattae (strain ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-74)|TrEMBL
MSFFHASQRDALNQSLAEAGPINVSFEFFPPRTSEMEQTLWHSIDRLSSLKPKFVSVTYG
ANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIARDYWENGIRHIVALRGDL
PPNSGKPEMYAADLVSLLREVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNYKQLQKFATMTNVRVPSWMSNMFEG
LDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A1L7D0E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium phocae|TrEMBL
MTPRLSASVPLDYFDAQPTVPLQRTALSFEVIPPRHDADAAKVDRLIDTLAAYNPDYIAV
TSSKRSGWLEGTAAFIEKISQRTTMRPLAHLACTAGNPQELTYWINRLVDSGVRGLLALR
GDLPAEGMPAGYLPHATDLINLIRDVERGQAARFAAGRLAVGVACYPCGHEESASPDEDF
DVLLAKQRLGADLAISQLFFDAEDFLRFKQRAQLAGVRMPLIPGIMPFSTPAKLERMAKF
SGLPTPVHLLERLGNDPDSGLELTAQLARTCLGGGAGALHIYTHNNPDLTVNLLNRIGIA
QP
>A0A0Q5BYZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. Leaf299|TrEMBL
MTRARFEIIPTADIAERARRAFPDPSAVVLTVTSLPKHGLERTLDAAVELAALGFGVVPH
LAARTVEGRPALERALGRLGDSGIGEAFVVSGDAKKASGTYSTSLELLRDAVEIMPALAV
GIAGYPEGHPHLSDESILKHLRERAPYIRSVVTQMCFDVDAVARYADSLRAEGIDAELWA
GIPGPVERATLLSLGAKIGVGSSLGFLTRSSSVAGGLLRGRRFDPTAFVGRLEAAAGDRL
HGLHVYTFNELDGLASFGS
>A0A4R7LVN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. AG258|TrEMBL
MSPPSLIEAHPNLSDTAPVALSYELFPPRSPAAAETLWTTIRELETTAPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIIGELLDIGVRGILALRGDLPKD
GVRPSDGALRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPSRHPESPSEEHDVEVLL
AKQRSGADFAITQVFFETEQYANLLTRARRAGVTIPIIPGVMPLTSLRRLTRLGELAGVE
PAPALMERLAAADSDLERLHIGVDATVNLANAALDAGAPGIHLYTFNEHQSALEVLDKLA
LPRHSRLGTRRDSAARPQLAS
>A0A2Z6CTU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. HK-01|TrEMBL
MCMYHTHSPTVSLFQKAAQAGEFLVTAEVAPPKGGNPAHTIEMAATLKGRVHAVNITDGS
RAVLRMSSLVASAILLQNGIEPVCQMACRDRNRIALQADLMGAHALGIRNILALTGDPVK
AGDHPDAKSVFDLESVRLLQLIQKMNQGVDCNDKPLTDGATDLFVGAAVDPQCGSWSGLQ
SRFERKVAAGAQFFQSQLITDFERLEKFMDKIASVHNKPILAGIFLLKSAKNAQFINRCV
PGVNIPEHIIDRLAKAKDPLEEGVKIAAEQVQIARQLCHGVHIMAVKREDLIPKILDLAG
VAPVNQVLVK
>A0A0D8L4I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella planticola|TrEMBL
LAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTYGANSGERDRTHSIIK
GIKERTGLEAAPHLTCIDASRDELRTIAEDYWNNGIRHIVALRGDLPPGSGKPDMYAADL
VTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFR
DRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFEGLDNDAETRQLVG
>W6MNN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kuraishia capsulata CBS 1993|TrEMBL
MKITQKLENSHREPGAPATFSFEFFTPKTSQGVQNLYDRMDRMYGLSPQFIDITWNAGGR
LSSLTTEMIHTAQTVLGLESCMHLTCTNMSVEVIDNALKDAYDAGCENILALRGDPPIDG
TESTGDFAYAKDLIAHIRKRYGDHFCIGVAAYPEGHPEEHDVVKTIEYLKEKQDVGGDFI
VTQMFYDVDRFIAWCEKCREAGITIPIIPGIMPISSYASFLRRAKWSEINIPAEFLERLE
PFKDDDELVRDEGTKLVVEMCSKLLASGYVNHLHFYTMNLEKASMMILEQLNLIELNVST
QDQPWRKSLNPNRLNEGLRPIFWQNRKFTYITRTSNWDEFPNGRWGDSRSPAFGEVDMCD
GELIRHSPKKALSLWGSPESLEELSHLFIDYLQGKIISLPWSDGSISDEVNMIKDALLDL
NSRGFLTINSQPCVNGLPSNDRVHGWGPKNGYVYKKQYLEFFVPAELLRTLQDRIADANS
ERGGLYNILSFYAVNSKGDMVTNTKDSDINAVTWGVFPGREVVQATIVERVSFLAWKDEA
FRILKEWSTLFKSDTADQFANTKKLLSRIHEDFYLVNIVDNDFVTLQNQRIFKLFDGLQV
N
>A0A7Z0DLN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides panzhihuensis|TrEMBL
MATDQPTTSSEVDGRLLQMLTDATMEVIPLKGGPEQILATSPGATVAVTCSPKFGLSRTL
EQCEVAASAGRRVVPHIAARMVEDRAALRDAVRRVADLGVTDLYVIGGDAAAPIGRYGEA
GQLLDDLAEIEHPFTRIGVGCYPEGHPHIDDDRLWEALLRKQSSATYMVSQMCFDAEALT
TWLAQARARGVTLPLRVGIAGPLKLAKLTELSLRIGVGQSLRYLSKQHGLVGNVLLGRTY
DPVPLIRSVVSDKPGTDIEGLHAFTFNQVPVFRAWAKTYGAMS
>A0A7C7CU13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinaceae bacterium|TrEMBL
MIDILKQDKPAFSFEFFPPKDDVGFDQLFETIDNLKSWDPAFVSVTYGAGGSTRSKTIDL
VGRIKKEIGLESMAHLTCVGHSSDEILKVLESIKEQNVDNVLALRGDPPTGETNFTKPDN
GFGYAEELVQFAREHFSFCIGVAGYPEGHPESSNLKEDLFRLKKKVLAGASFIVTQLFFD
NKYYFDFVASLRKIGVDVPVIPGIMPIVNLKQIKRFTKMCGATVPPDLMVRLEKVKDDPE
SVCQIGIDHATNQCEKLLMQRAPGIHFYTLNRSRATLSVLERLV
>A0A8G1P5L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prolixibacteraceae bacterium|TrEMBL
MKIIEKINQSNKTLFSFELLPPLKGQDASRLYHTIEELLEFNPQYINLTTHRDEIEYKEI
KTGVFEKKTVRKRPGTVAIAAAIQHKYGVPVVPHVLCAGYSKEETENMLLDLHFLGIKNI
LALRGDSLRTENLFKPQEDGHKYAVDLVHQISDISTGKYIDPDIKNKTCLDFCVGVAGYP
EKHFEAPNLNFDLDNVKRKVDAGADYIVTQMFFDNQKYFDFVDKCRAIGITVPIIPGIKP
LSKKVHFSLIPRIFSLDLPEPLAKELQRCKTNDDALRVGTEWAILQAKELVKNNVPSLHL
YTYGLADNTKEILKSIF
>A0A7Z7FNS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium fabrum|TrEMBL
MLRSETARCDGDIRLSFEFFPPKNAEMEAQLWETVAELKKWDPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYQ
PHPEGYENAAALVKGLREIGDFEISVSAYPEKHPESASETVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTVAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFEGYD
EDLEGRARVAAEVAAEQIADLQRRGFNEFHLYTMNRAPLVDAVLENLGLQRLRRSAA
>A0A8F9QT29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri|TrEMBL
MPADMPSGASTITDTYSLEVSVKDIGALTNAAPRILPGSDMFIPYLPGQTEAARLAAAQR
VRRLGFEPVPHLSARRIGSLEELQAVIARLVGEADVTRCLVIAGDPSTPKGPFADSVSLI
ETGVFERSGIRTIGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDADI
VMTWLEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGNA
GPDRFVDRLVSRLTEAHGDVRLHFFPFGGIAQSVEWVAHYRSCEASQDRVSSVAAD
>Q1D7X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcus xanthus (strain DK1622)|TrEMBL
MKIRNRLNPSDPCFSFEFFPPRTDEGEANLLKALEDLATLQPGFVSVTEGAGGSTRAKTV
ELVLRIKQEAGIEAMAHLTCGGHSPAELRTVLERLSAAKVDNVLVLRGDPPKGQTVFEPA
PGGFRYASEMVRFIREEDFNFCLGGACYPEGHVETPSRDDDLRHLKAKVDAGLDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQIQRFTRLCGATVPMRLALQLERVKD
NPEAMAQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRARS
>A0A1Y3CLX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4999|TrEMBL
MTKRIPVSFEFFPTKTDVGAEKLRVVHQELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYASDLVA
FIRQHSGDHFHIEVAAYPEMHPQAESFDKDIQNFITKARAGANSALTQFFFNPDAYFYFV
DRLQKEGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHVEPNRQLVLDLGLA
>R8HIG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus BAG1O-1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTLKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKSHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEVAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1H6HKG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium culicis|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVGQINNLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIDFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNDAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKIAGELF
>A0A2S0MLL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pukyongiella litopenaei|TrEMBL
MTPPKISFEFFPPQSLEASFRLWDTVQVLAPLGPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNASREETLAIARDYAEAGVTEIVALRGDPPKGSGQFVPHPEGFGSSV
ELIGALAAMGRFDIRVGAYPDIHPEASSAGADVEWLKAKLDAGATEALTQFFFEAETFFR
FRDACDKAGIDASRITPGILPIENWKGARNFARRCGTHIPTWLEAAFETAQRDNREDLLS
VAVCTELCSDLIDGGVDTLHFYTLNRPDLTRDVCHALGVTPNAELRNVA
>A0A397NI65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas oleovorans|TrEMBL
MSNPCSNFIPYTLEVTGKGIHEVEQARAVIPAGTPINIAFLGNEDHAQRIQAAKVIRACG
GEPVPIISSRRLRSEEDRDELIGALIEQAAPKRFMFVGGDPATPAGPYQDSLVLLASGVL
ERHGIDQVVITGYPEGHPKIDSGELMRALKWKLDFLREAGCRVEITTQFGFDAEAVVRWI
ERLRQQGIDTPVRIGVPGPADVGKLLRFARQFGVATSASILRRYGLSMTNLMQRVGAERY
WDQLQAGLGDRRLGSIGWHLYPFGGVEDGVTWINARLSVAASPQASSR
>A0A3S9N2B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cenocepacia|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLMPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAATATRTICERLAM
>U4Q5R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium pusense|TrEMBL
MWRKRRFYFAPGGHDMLRSETARRDGDIRLSFEFFPPKNAEMETQLWETVAELKKWNPDF
VSVTYGAGGSTKAPTLDAVRRMIGDSHLATAAHLTCVDASRDEVHQVVDEFRNAGVRHFV
ALRGDPSTGIGTAYQPHPQGYENAAALVKGLKELGDFEISVSAYPEKHPESASEAVDIDM
LKRKADNGATRALTQFFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCG
TSIPAFLDERFEGYDEDLEGRARVAAEVAAEQIADLQRRGVSEFHLYTMNRAPLVDAVLE
NLGLERLRRSAA
>A0A263DKX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. MH-G8|TrEMBL
MTSEADRAAPDAVAHPPRPGVSPRQLLARALRGASYEVLPFRSTEEAVVTHVPREVALTV
TTTEAKGLERTLDLAESLSRHGYGVAPHLAARLVRDKAHLTDVVARLGEAGVTSAFVIAG
DAPEPAGPFPDALSLLEALDALGRPFRSVGIAGYPEGHARIDDHLIEKALHRKAPHATHV
LTQLCFDAATTAGWARSVRERGVTLPLRVGVPGVVSRQKLVRISAGLGLGQSARFLAKQQ
SMFWRFFLPGGYRPDRLVDRLAPALGGPLHGLHVFTFNELEKTEAWRRDRIARLAAEAS
>A0A430H4U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. 679|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPQFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIKSFGLDVV
TDLCARLQEGGAPALHFYTMNQSVATLAVLERLD
>G6YCQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium amorphae CCNWGS0123|TrEMBL
MIARQLDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRNNVPGIHIPDAIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLGHILHDEITETQVDMVK
TAH
>A0A210W0P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia sp. K82|TrEMBL
MSFPISFEFFPTKTPEGAAKHVQVRKNLYARKPQFCSVTYGAGGSTQAGTFNMVRDIQSE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPHSDLEAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A1F4K787|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFCSPLOWO2_12_FULL_61_40|TrEMBL
MTELSRIPVSLEFFPPKTPEGADKLRLVRQQLYALQPEFCSVTFGAGGSTQEGTFNAVRD
ILAEGVSAASHFSCVGATKVTVRAQLGVLKAMGVRRLVALRGDLPSGYGAGGEFHYASDL
VEFIRAETGDDFHIEVAAYPEIHPQAKSPASDLQAFAAKVRAGANSAITQYFYNADAYFR
FVEDVDGLGLDVPVVPGIMPITSSTQLMRFSDASGAEIPRWIRLRLQSFGDDMASIKSFG
LDVVTDLCEQLRAGGAPALHFYTMNQSVATLALCDRLGLAPRLQ
>A0A5J4S9G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
MKVTDLLYDSKQTAFSFEILPPLKGNGIEKLYRTIDVLKEFSPKYINITTHRSEYVYTDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLIDLQFLGIMNL
LVLRGDKAKHESVFTPEENGYTHAVELQEQINNFNRGIFIDNSKAQEITVPFSYGVACYP
EKHEESPNIDTDIYWLKKKVEAGAEYAVTQLFYDNRKYFDFVEKARKAGINIPIIPGIKP
FKSLSQLTMIPKTFKVDLPKELSHEIQKCKNDNEACRVGIEWCTVQCKELIAHNVPSIHF
YSIAAADSIKEVAKRIY
>A0A2M9Q5U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus xylanilyticus|TrEMBL
MGLLERLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQKPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLEQI
LATVDEQATVLLAGNPDGLLLETYYDFEELTATLSMLRAKTKLPIIAQVSMHEPGILQNG
MSLNNALHELESLGADIVGVNCRLGPHHTIQAFEGVELPEKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVEEKHAKPEKIEV
VREAEPANYEPLHIKVKRERSIIVELDTPRHLEIEGFIEGAKKIYGAGADVVMMADNSLA
SPRISNVAMGALLKETHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVSR
LEKKIEHGADYFISQPVYTKEKIVEIYEATKHLETPIYIGIMPVTSYKSAEFLHHEVPGI
KLSDDALSRMKACGDDKERATLEGIAIAKELVEVAAEYFNGIYLITPFLRYDMTLELMQF
IEQLDEQKKGVSING
>A0A836SS39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiritimatiellae bacterium|TrEMBL
DGFLLSFEFFPPKDHRGFAVLEKTVSQLRILEPDFVTVTYGAGGRTRARTLALAELLREI
GFRPVMPHLTCISTAARDLSRIVDEIAARGFRNIMALRGDPPAEGGPRPEGLPHAINLVR
LIRSRHPDICIGVAGYPETHPEAPDPDTDVRHLKEKLEAGADFVITQLFFDNRFYLQFVE
RCRRHGISQPIIPGLLPAVSLPQVERIMQLCRSTTFPPDLRSALEKVRDDPVQSERIGLE
WTRNQMAGLFESGAPGVHLYILNRTRTALAPLLRDFLAAHRRA
>A0A059DC08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eucalyptus grandis|TrEMBL
MKAIEKIREALDGRGDEGEPVFSFEFFTPRKKADVNALLDLIGRLVVHGPAFCDLTWRTG
SLATDDITLDMVGKMQNAVGVETMMHLTCTNMPVQRIDRALDRIKSDGIRNVLALRGDPP
TGQLKFVPVPDGYGSGLDLVKHIRDKYGDYFGITVAGYPEGHPDVIGSNGVASDEDYKNE
LAYLKRKVDAGADLIITQLFFDTDIFLKFVNDCRQVGITCPIVPGIMPIATYKGFARMTS
ICRTKIPAEVSAALEPIKDNDEAVRNYGIHLGTEMCKKILASGIKTLHIYTFNKEASAVA
VLMNLGLIGEAKVSRSLPRRHPAKVLPVEEDQHPNSNTTEAEKKF
>A0A2H5VWD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR10|TrEMBL
MSATFLDRLHREVLLADGAMGTLLLARGIEPKALMEQNLTRPELIREIHLEYIRAGAQVI
ETNTFLANRLRLAEYGLESELEAINRAAVRIAREAVRMSGEEVFVAGSVGPLGALVKPYG
NLTLADLSAAYVEQIGILVDEGVDVIIIETHPSLLEALEAVRAARTVSPTTPIIAQMTFL
EDGKSKFGDDLRRSLEALAAADADVVGVNCSGPQMTYDIIVDFLTTTELPISIMPNAGVP
QFIGGRTIYLSSPEYLREYARRFVEAGANILGGCCGTTPEHIRAMSAVVRGQVPRRVRQR
LVVSVSGEAASGAPSTASLPARFRERLGREFVVTVEVHPPRGVDYRAEIAMIRQLARCGV
DAVSIHDPPGARVSLSGLVFAHVVQTQAGVEAIWHLSCRDRTLAMVHSELLGAAVLGVRN
ILALTGEAASVGELPRAPSAHDVSATGLVKIIEGLNRGRTLMGNDIGTPTDFRVGVLVQV
GADDLEAELRKLEERVQAGAHFIVTTPVFDLERFDVFLKRIAGFRLPILVGVLPLKSARH
AEFLHHEVPGITIPEALRRRLHRAQGDEATEGLRIARELIAALRPHVAGLHVIPPVERWD
ALPEFLRTCLPQERMAESLGA
>A0A8J8BNY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeota archaeon|TrEMBL
MSKLSENFGKTFIVTGEIAPPRGPKLDEFNHELEEIKKLMPKLHGVNVVDIPGSLLLMSS
LAASIMLKQNGVEPIYQLVCRDRNMLALQADLIGAAAFGIENVLALAGDHPACKSSDHPT
AKPVFDLDSTTLTMAMKAMNQGKDITGRELNRATNFFVGAALAPGATPLDGEIYKAKRKL
NAGADFFQTQTVFEPSLMENFLDSYEKLISEDLRDKVLVGLVPLYDYDMVQFLRTIPGII
ISDETANKIKNASDPVEEGVNLVAGYIDMAKEIGLAGVHLMPAGKVEALVRLVEGL
>A0A7Z8QNA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium CS1|TrEMBL
MTIKNKADLFSFEFYPPKTEQGDLNLEQVHRDLAKLNPDFFSVTFGAGGSTRDKTYDTVV
KIQKNGVSAAPHLSCVASTKENIREILANYREHGVSKIVALRGDLPSGMMSAGEFRFANE
LVDFIRAETGDHFQIHVAGYPEVHPQAGNATEDFNNFKRKVDAGADAVITQYFYNAEAYF
YFLDKCEKSGINIPIVPGIMPITNYAQLFRFSDMCGADIPRWMRKTLECFGDDKASIMAF
GEDVVSKLCQELLDNGAPGLHFYTMNQSKPTLAVWDNLSFA
>A0A5P2D6Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces venezuelae|TrEMBL
MALGTASTWTDRARTVHELLVSGRPTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGTTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALR
GDPPGDPMGEWVPHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSSDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVF
PRDVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQRA
>A0A4R7FK22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp. JUb58|TrEMBL
MSFPISFEFFPPKTPEGAEKLRVVRQALYARKPQFCSVTYGAGGSTQEGTFGVVKAILDE
GVDAASHFSCVGATKQTVRAQLQQLKDMGVKRLVALRGDLPSGYGLGGEFHYASDLVTFI
RDEFGQDFHIEVAAYPEMHPQARSPEADLQAFLAKVKAGADSAITQYFFNADAFCRFQED
LQKRGVDLPVIPGIMPITGSTQLMRFSDACGAEIPRWIRLRLQGYGDDVASIRAFGLDVV
TQMCEDLRRRGAVGLHFYTMNQSAATLAICDRLGL
>A0A3E0HZ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kutzneria buriramensis|TrEMBL
MTSVVERLRGPRPVFSVEFFPPRDAADEQRLWLAIRQLEGCEPAFVSVTYGAGGSSRDRT
IRTTGRVVQETSLLPMAHLTAVNHSVAELRNVIGWYAAVGVHNVLAVRGDPPGDPNGEWV
RHPKGLTYAEELVTLIRQLGDFCVGVAAFPYGHPRSTDLDADTENLVRKFRAGASFAIAQ
LFFEAEDFLRLRDRVAARGCDAPLLPGILPLTTVRTLHKTAELAGAPVPPSVASRLDRFA
DDPKAFRAAGIDVVTELSQRLIDEGVPGVHFYTFNMSKATTEVVARLGLLPARA
>A0A1X4HZ82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 13-12-16|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHTVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVHAAGCETPVIPEVMPVTSVKMLERLPKLSNAVF
PEALKERILAAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A2U1R320|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. HTF|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMDFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
IMALRGDAMKDEQYFIPKAGGNDYAIDLVRQINLLNQGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVKKHLQVLPQIFRIDLPEDLIHAVDQCKDNAAIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASHIF
>A0A3B9IYH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKIRDLFEKKTVFSFEVFPPKKTSTIDVIYDTIDELRELNPDFISVTFSAGGSSNNALAL
DLASKVKEYGITPMIHLPCINYTKDEISATLSEIQERGIENILALRGDINPEIPPKKDFL
HASDLIEYINSKGEFDIAAACYPEGHPDAESLERDIDNLKIKVNAGADHLISQLFFDNSY
FYYFREKAVCSGINVPIEAGIMPVVNKRQIERMVTTCGASLPHKFVKIMQKYEHNPEALR
DAGIAYAIDQIVDLLAGGAEGIHLYTMNNPYVARKISDAVKGIINV
>A0A1I8JJU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
MESQQNGHAYESDAPKILCRVSSGDSSSSASNATEMNDCHDSRPHSPVLPIAQYRPLISR
INRRIEKGKRWFSCEFFPPRTASGAVNLLSKFDRFAKGRPLFCDVTWHPAGNPMSDAPTS
SIMVASAMLNYSGIDTMLHVTCVGLPEERMTAALERAKGLGLKNILALRGDLPEAPEDGA
GGSGDVNNGDLLGDFKYAVDLVRFIRKRYGSFFNICVAGYPTGHPEASSYADDLLRLKEK
PDTFLKFQSDCRQLGIRCPIIPGVLPIQAYQSLRHIVKLSKLAVPDEIIRTIEPIKENDE
AIRNYGIFQCTQLCRKLLESGEVHGIHFYTLNREVATIEILRNIVGLWHEDLPRPLPWKH
SANHERCGELVRPVFWSNRPTSYVHRTLHWEEFPNGRWGRPDAPAFGELKDYYLFYLTVR
ATKKDRLNMWGEQLASERDVWRVFVNFVSGEPNANGFRVTRLPWSDEELQQESRAIRDQL
VALNSRGVLTINSQPNVNGLPSGDSTYGWGGPGGYVYQKAYLEFFLPGQFLAALEQVLDR
FSPRVNYQIVNREGTVNRLNFSQQEPIALTWGVFPASEIIQPTVCDNGAFMAWKDEAFGL
WTQEWANLYPEGSDSRRIIQGIAEDYLLVTLVDNEFPAENCLWSVVEQVLTTQSQQGALV
>A0A1E7JAB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium C00003063|TrEMBL
MDAADQNSNSTNSYSLIAEIDPPKGANLAGFLDTALKVRGRVDSVRVTDSEHAIMRMSPI
APCLALLDKTIDPIMIITGRDRNRISFQADLLSAAALGIKKIVIKEGHDPAEGDQPVART
SGDLDLVSMLQCAAALNSGKDLAGESLDGGTDFEIGVSVELSDDVNFNRERAEFFMQLGD
YGVTSVTLGPTYDINIVEQFVPFAEKTGIKLYSSLMFLKSVTMIRYLNNLTGAPSIPQEF
LKKMMQAPVKKDAGMQVAADFMEELSTLGDGIVLLAIGWKGRLPEFLDLIDR
>A0A401XLZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermaurantimonas aggregans|TrEMBL
MKVIDIIRNAKETLFSFEILPPLKGDNIYDVYTNIDPLMEFKPPFINVTYHREETVLRPL
PNGLYEQKVVRKRPGTVGLCAAIMHRYKVEAVPHLLCGGFSKEETENVLIELDFLGIQNV
LALRGDSQKGQRYFIPEPDGHHYAYQLVEQIQNLNRGIYLDEEIENNTPTNFCIGVAGYP
EKHFEAPNLSIDIQNLKRKVDAGADYVVTQLFFDNRVYFDFVDKCRQAGITVPIIPGIKP
LATKKQLSLIPHMFHVDIPDDLSIEILKAKDNTAVRQIGIEWAIQQSLELKKAGVPVIHY
YSMGKSDNIYKVAAAVF
>A0A1J0TXC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 2G|TrEMBL
MDRLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERLGPAFVSMTYGAGGSTRDRTV
RVTGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWEK
HPEGLEYADELVRLVRELGDFHVGVASFPEGHHRSPDLDHDTRYLVQKLRAGAEYSITQM
FFDVEHYLRLRDRVVACDAEQGLKPIIPEIMPITSLRSARRSLELSGSHLPPVLEERLRR
AAGDGPEENRAAVREVGIEVATEMCERLISEGAPCLHFITLNFARATGEVLDRLGYELEA
PAAVQPA
>A0A0Q7Q1H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root140|TrEMBL
MRNKLDVGGKTRNQTMRRLLEQARYEVLPTESTEQKVVENVPLDRMITVTASPSKGLGAT
FDLAERLTGHGYAVVPHLAARMVSGRSELAEICERLTSGGITRVFVPGGDAEPAGDYPDA
LSLLEDLVALGRPFAHVGITGYPESHPQISDDMTVQAMWDKRRHATHIVSNLTFDPAVIK
VWLERMRKRGITMPLLLGMPGPVDRTKLLGMATRIGVGESTRFLAKHKGTFARLAAPGGF
TGERFLARCAPALGAPTAFVEGLHVFTFNQIAETEAWRTDLLQRL
>A0A4V1Y5T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum subsp. globosum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLTEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAF
IRERRPDMNIYGACYPEKHPQADTLDHDIDNLKRKVDAGVTHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDHWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWTNVQDLFA
>A0A1W2BWM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter africanus|TrEMBL
MKITDHIINAKGKTLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDNAFIPTPNGHAYASELLQHVVDMNNGKYLHDDMESPEKTDFCIGVAGY
PEKHFESPNLDTDFRYLKHKVDTGADFIVTQMFFDNQKYKAFVDKCRENGINVPIIPGLK
PITSSKQLISLPKIFHLDIPVELSEAIQTCKSEKEVKEVGIEWMINQCNELKAMGAPVLH
FYTMGNPEPTKRIARAIF
>A0A495S5I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium limicola|TrEMBL
MKVTQHIEAAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNNLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKQGGNQFAVDLVKQINQLNCGKYLHDVMDVDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDQCKNNAEIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A2M7CD54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG03_land_8_20_14_0_80_45_14|TrEMBL
ARLGKKVKAGCEFIQTQCIYNIEKFARWMEMVRERGLHERCAILAGVTPFKSVGMAKYMK
NSVPGMDVPDAMIERMRGVPKERQSEEGIKMCVETIQKLREIPGVRGIHIMAIEWEEKVA
EIAKAAGLLPR
>A0A4V1Y6U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum subsp. globosum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLTEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAF
IRERRPDMKVYGACYPEKHPQADTLDHDIDNLKRKVDAGVTHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDHWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWTNVQDLFA
>A0A3M5N4U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. nerii|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>A0A433KMC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas andesensis|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLMHVRDELAARHPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSVGELRYANE
LVEFIREETGDYFEIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVEKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSDAIAAF
GTEVVSRLCERLLDGGAPGLHFYTLNQAAPVLEIVDNLRG
>A0A1H9LSW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gallolyticus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADIIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAREAAGDDAFVLGTVGALRGLKQCDLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEAELIKAAKQLETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKETNFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDGLADLIRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALEHFKGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A243J6X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar pirenaica|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>C1DIB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azotobacter vinelandii (strain DJ / ATCC BAA-1303)|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARRLAGCDPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSRAELRSLLNTYKDAGIRRIVALRGDLPSGMGLANGELRHASDL
VEFIRAETGGHFHIEVAAYPEMHPQARNLEDDLARFAAKMKAGADSAITQYFFNADSYFH
FVERVRKLGVEQPIVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFG
EQVVTAMCEKLLEGGAPGLHFYTLNQAEPSLAIWNNLGLPR
>A0A8I0E3Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alloprevotella sp. Lung230|TrEMBL
MTIPELIAGNGTAFSYEVLPPLKGNGIDGLRKTIDRLREFEPKYINITNHRAEYVYRKVE
GGLMERLHTRRRPGTVAVAAVLQRECGIPLVPHVLCSGYTREDIEYRLLDMQILGIENLL
LLRGDKAREDAVFHPTEGGHAHTTDLQMQVNEFNAGRFVDGTPIRQPGQPFSYGVACYPE
KHEEAPNLESDFQMFKRKVELGADYGVTQLFYDNAAYYRFVDRCRKAGITVPIIPGIKPL
SKLSQLTLVPKTFRCDLPEPLAHELFRCTTDEAVKQVGIEWAVEQCRDLIAHGVPSIHFY
TVSAVDSIAQIAPQVY
>F0Q3G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax avenae (strain ATCC 19860 / DSM 7227 / CCUG 15838 / JCM 20985 / LMG 2117 / NCPPB 1011)|TrEMBL
MSLSTHRAALPVSFEFFPPKTPEGADKLRAVRQQLYARRPEFCSVTYGAGGSTQEGTFGT
VREILSEGVQAASHFSCIGATREGVREQLAQLKAMGVSRLVALRGDLPSGYGAGGEFHYA
SDLVAFIRAEAGDDFHIEVAAYPEVHPQARSPEADLQAFATKVRAGAHSAITQYFFNADA
YWRFVDDVRALGLDVPVVPGIMPIMGSTQLMRFSDACGAEIPRWIRLRLQGFGDDSASIR
AFGLDVVTELCERLRAGGVPALHFYTMNQSAATLEICRRLGL
>A0A835X524|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon|TrEMBL
MTIRYELNPPKVKEESLLSHEDLENALQKLKERVLKIEKLCNGIHITDSVLGIPRISPIT
TGTLIRNHNSKMEITVSLRVRDRNLTSLVQSISDAILLGLNGILILKGDPPPEGPKDSKL
VPSQVVKYFKQLNLGEKIDLFLSLPSNPNFDKIHNKIEAKPTGFVTQVIHSVEQVSRIVD
YLKPQGFKIIPCILLPSKENAPSAKYLNLDWSSYSDNPIDFIKEIHKIAGDVLITSPNDF
NGAYETFTKLAS
>A0A3N5S3V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon|TrEMBL
MVDIKVIYEMNPPKVLYNNYFDNKTINKNIDLFLSRTKRISEFVDGIHLTDNVLGIPRVS
SLIIVSMLKKMGIAKPISCTCRLYDKNLISVLQFVTDSIIAGVYSILILRGDEPVIGNKI
IDIPPTKIIKTLSEHNFNNFIKLDLSFPNRIENSTKIKNKLEARPRAFVTQSISSIENLK
AIVDVSRPFGIDVIPCIMCPSKRNEVSAKNIGLDWSSYV
>A0A2A2R8N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium Tous-C9LFEB|TrEMBL
MANLIDALEDRILIGDGATGTYLYSLGIGSDHCLEEANLHQPELVTRVYNEYIGAGAHII
ETNSFGANKFRLSRFGLEDKVNEINWRAARLAVDAAKGKNVFVGGSVGPLSLRPTDPPLS
ESDRKAFFREQIGALLDGGVNYISLETFTDLSELLLALDVFQNLSNVPVCTALAVSEEGR
LASGQDLATAWKKLREAGADIVGINGTVGIQASLYLLSGIEVGIDDRIAVYPNAGKPAFY
EGRFNYEASPEYFAENLPRFVAEGANLIGGDYGTTPAHIAALAEAAKELKPVRQKAARTK
SRVTVTGKTATPATVESEEESLLDQVKHKVVSIVELDSPKTLSMDKFLTGAQALKDAGAA
AVTLADNSLAILRVSNFAAAVLLREKVGITPLLHLACRDRNLLGIQSELMGIGILGFRHI
LAISGDPAKVGDHPGATSVYDVNSVGLIKLIAGMNRGVNAVGKGLNGQTKFVIGCAFNPN
ALNFDSQVKKLEMKIAAGAQYVMTQPVFDPALAKMTAQRLKPLGVPVFIGVMPLLHSRNA
EFLHNEVPGIKIPENVRERLRAADEKDGAAIGLELAREIRQTVLEHFNGIYLITPFLRYE
LSLELLG
>A0A2A3T1R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon|TrEMBL
MLLIYRSKVLIMYNQKPPMTVRYEINPPKISGDGQDVRNVLFERIETISSVCNGIHLTDS
VLGIPRVSPFEIAKQIRESNKNIKLTCSLRVRDKNLNDIEKIVQESIGTVDGILVLMGDK
SDTMPNKDNLIPSQVVKALNDNGLDKKIELFLSLPSNPNFAKIQKKIDAKPVGFVTQVIH
SKDQVEKIVNYLRPNGFKIIPCLLLPSKNNLKSAEFLKIDWSNYEENIIEFINEIHSIDS
EILVTSPNDFKRAHETLTKLAT
>W9G587|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Intrasporangium oryzae NRRL B-24470|TrEMBL
MAHGTASSMVRAERFTRSIPAMVEADAPSFSFEFFPPRDDAAEAQLWEAIRRLEKLSPSF
VSITYGAGGGTRDRTVRVTERILEATSLTPMAHLTCVGHSVAELRHVVGHYASVGVRNIL
ALRGDPQGGLGQPWTRHPEGLDHADELVALIRTLGDFTVGVAAFPDGHPESHGFAEDAET
LVRKEAAGAEFAITQMVFDVDHYLRLRDEVARRGSSLPIVPAIMPITNARQVVRMAELAG
QPMPTAVTDRLARHGDDPAGVREEGLAIATEASRRLLEEGAPGIHFITMNRSSATLEVFG
NL
>A0A3P1SJQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amphritea balenae|TrEMBL
MIFHDEPNAGDPFPHLPDHSSQGRLERVLRAGHFAVTSELAPPDSANPEDVYDRARVFDG
YVDGMNATDGSGANCHMSSVGMCALLTRVGYSPVMQISCRDKNRIAIQGDVLGGAAMGVT
NMLCLTGDGVQAGDHPEAKPVFDLDCMSLLETVRGMRDKHEFLSGRTITDAPKVFLGAAS
NPFAPPYDFRPHRMAKKIAAGAQFIQTNYCFDIPRFKEFMARSRDLGLLEKVFVLPGVGP
MASARTATWIRNNVPGIHIPDEVINRLAGAKDQKKEGQQICIDLIQELREIEGVSGVHVM
AYRQEEAVAEIIDRSGVLDGRVPWYPGRDEELLKERA
>A0A0S8GIH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillales bacterium SM23_46|TrEMBL
MDSQAKFSRTFSCEYFPPKDEDARAKLDETTRELATLSPAYFSVTYGAGGSTRQGTYETV
RALHEKGLTAAPHISCVGASRESIRDQLLGYKALGIKRLVALGGDLPSGMASPGEFRYAY
QLVELIRAETGDWFHIEVAAYPEVHPRATNAEDDLAHFRHKIDSGANGALTQYFYNADAY
FCFVDECERIGVDTPIVPGIMPITNYKQLARFSDGCGAEIPRWIRKRLEGFGDDLEALRA
FGLDVTTELCRRLLDGGAPGLHFYTMNRAGPTRAIWQRLGL
>R6LGB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides clarus CAG:160|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESAFTPEGNGYHHAIELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTKEVLKCKNDAEAQQVGIEWCVQQCRELMEHRIPSIHF
YSIGAVDSIREVAKQIY
>A9HNY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / CCUG 37298 / CIP 103539 / LMG 7603 / PAl5)|TrEMBL
MPLAPRFMSVTYGAGGSTRDRTLDIVASLVRETTVPVAGHLTCVDASRDQVDAVARAYWD
AGVRHIVALRGDPAEAGAAYVPHPDGYANAAALVAGLHRIAPFEISVAAYPETHPAAVSA
AADLDNLKAKIDAGATRAITQFFFESETFLRFRDHAASAGITAEIVPGILPVGNIAQAYR
FADMCGARVPDWMRRLFDGLDDQPGARAIVTTTVATELCRRLREEGVDHFHIYTLNRADA
SLALCRLLGR
>A0A1H1TLU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microlunatus soli|TrEMBL
MERSGPTVVGEVADRPRRRRTRPSGIARRQPRHPALQSVLSRPRFEVLPTPGVEAQVITE
LPTDATVTVTASPRQGITATVDLAIGLAGRGVHAVPHLSARLIPDTSVLRRIIGDLEDAG
IDEVFVIGGDPTEPVGEFGSALDLLSAMRTIGHRFTIGIAGYPEPHPRIADDLTIQAMWD
KRREASYIVSQLCFDPKLLTSWIRRVRRRGVQLPILIGVAGPADVAKLLRIGRRIGVGGS
ARLLSHHTGLLRVARPGSWRPDGLLGDLEPAFADPSHGLTGVHIYTFNALRAAERWRREM
LQQNGADPP
>A0A7W9ULW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia transvalensis|TrEMBL
MSFDNVGGRPTSGRTPRVSGTPSVVGQLVKRADGTIPFSVEFNPPRDEAAEARLWRAARE
FERMHPAFVSMTYGAGGSTRDRTARVTGQLARETTLLTVAHLTAVEHSVAELRSIVGTYA
DAGIRNLLVLRGDPPGDPLGEWRRHPEGVEYAEELVRMVCGLGDFHVGVASFPQGHHRSP
DLDHDTAYLCAKLRAGAEYSITQMFFDVEHYLRLRDRVAACDPVEGAKPIIPELMPITSL
RTVQRAEELSGRPVPRRLMERLERAAGNDPEANRAAVREVGIEIATEIGRRLIEEGAPCL
HFITLNFAKATTEVLTNLGYTVTAAPARA
>A0A6N8AY94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MTALSFEFYPPKTDDQRAQLDRTASRLKAHAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLQAAPHLSCVGGTREEIRELLKLYRAIGVRRIVALRGDLPSGMGFPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLRHFKAKIDAGADAAITQYFYNADAYFQFVDA
TRRLGVDVPIIPGVMPISNFSQLRRFSEQCGAEIPRWIAKRMQAYGDDVDSVRAFGADVV
AALCERLIAGGAPALHFYTLNLARPTNAVLQRLGRG
>A0A8I0GUG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTASRLKAFAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYAAELISFI
RAEHGDAFRIEVGAYPETHPQANDALLDLKHFKAKIDAGADAAITQYFFNADAYFHFVDA
VRRLGVSVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAESVRAFGAEVV
ASLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLRG
>A0A2Y9KAX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enhydra lutris kenyoni|TrEMBL
MVNEPRGDGGPPPRSEGSSSGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSQGQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRH
IRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSRLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFAHYLSGEPNQHGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKVTVDGVWIIGPGKTRITEALVSSQVARGSLAGQTHSNRSTDP
>A0A8E2BFI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter lissarensis|TrEMBL
MRLSVTRSDLDEAIGALVGNFSIEALPKDTQKFDDLRDHLPAGTRVYVAYTSGSTAEIVD
AAEKLRHQGMEPVPHIPARRFASHDELKGFLGKLAARAAVKQVLLVGGDVARPEGPYAAS
LDVLRTGMLEGHGIEAIGLAGHPEGHPGVAREALRNALIDKCEYAAKVGLDVSLVTQFLF
DTDKLFAWHADFVENAAPGIAVDVGLPGLAKMTTLMRFAKDCGVGASFGMLTRHAGRAFK
LATSFSPEDTLLELADGVRKSGRPIFRSVHFYPFGSFEKTAEWLRGLQSQRPARGQPHLA
EAL
>A0A380BBD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium spiritivorum|TrEMBL
MKIIDHIQNAKGKTLFSFELLPPAKGQSIQSIYKTMDELMEFKPPFIDVTYHREDYLYKE
HANGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARRGDADFIPTEGGHSFATDLLEQVANMNQGRYLHEDIETSEKTNFCIGVAGY
PEKHFESPNFNTDFKFLKKKIEMGAEFIVTQMFFNVQKYKDFVTKCREHDINVPIIPGLK
PITSKKQLVTLPRVFHLDIPEELSDAIADCHTNADVRQVGQEWLVQQCRELIEFGAPVLH
FYTMSNPGPTKKIVEQLF
>A0A151XXF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pragensis|TrEMBL
MSKNIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKERIAELLDLYQSQGINRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGDHFKIEVAAYPEMHPQADSFDLDIKRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLV
>A0A1I3MS93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Celeribacter halophilus|TrEMBL
MTKAPNISFEFFPPKNIAACFSLFETVQALRDMQPGFVSVTYGAGGTTRELTHDAVALLT
RKYGWNVAAHLTCVNATEEETLAIANSYKEVGVNEIVALRGDPPKDAGKFTPAEGGFANS
VELIAALKETGDFKIRVGAYPDPHPDAEDETSDITWLKQKFEAGADSAITQFFFEPENFF
RFRDRCARAGIKGEIIPGILPITSWKGIQRFASACGTPIPISYEAAFEHSQDHHKLSVDL
CTKLCEKLIKEGVENLHFYTLNRPTLTRAVCANLGVV
>A0A1R4GWN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter rhombi|TrEMBL
MPHDSNGAAPPALSFELYPPLDNSAVPKVVKTIGELAQARPDYVAVTYSGAPQRREATLE
LVGHLASNTRLRPLAHLTCVGESRASLTSLIERLIGSGVRGVLALRGDLPVDRATSRGDL
PFARHLIELIRDVESRHSAALCAGRLSVGVAAYPQRHPESPSFEHDVEVLLAKERSGADF
AISQVYFRPSDYARLLQSARDAGVRIPIVPGLIAFDSVRRLTRLSGLAGIEPDPVLAHRL
ETARDADERRRIGVEAAVDLGRNALNDGAPGLHLYTFNDHRGPLDVVGRLGLTGRFGDPA
PRPGRLTAVPA
>A0A133YAL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium KA00344|TrEMBL
MSLRSFLKDNKDTAFSIEILPPLRGKGIQGIFRNIDKLMEFSPAYINITTHRTEQVFREI
EDGIFTSDTIQKRPGSVAVASALKGRYKVPTVPHIICSGFTKQEIENQLIDLNYLGIEDI
LVLRGDRERGFNQFRAVNKGHLHAIDLCKQVNDFNEGKMTDGTETDPLSNKFCYGVAGYP
EKHEEAMNLETDLTYLKEKVAQGASYIITQMFFDNQKYFDFVRRCRNIGITVPIIPGIKP
LTSFSQLSLLPKVFHIDFPNDLSEELIKCRNNDEVKALGIEWGISQARELKEHHVPSIHF
YTVNATASVQQIAKRVF
>R6DMI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:242|TrEMBL
MKLNTLFEQKKIVFSFEVFPPKKTSSIQTIYDTLDALSDLNPDFISVTYGAGGNPADHST
VEIASTIKHKYHIEPLAHLTCLNSTKEHIGQVLDELRANEIENILALRGDRNPDVPPKTD
YRYARDLIEELNHHGEFDIAAACYPEVHPECPDMEEDILHLKEKVDAGASHLISQLFFDN
NDFYNFLYRVREAGIMVPVEAGIMPVTNRKQIERMVSLCGASLPKKFVKIMHRYGDDPAA
MQDAGIAYAVEQIVDLISNGVQGIHLYTMNNPLIARRISQSVASLIRCSNRAE
>A0A1H4IZZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor aquibiodomus|TrEMBL
MTRRPPQIDENPDGVDLPLEPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANAQDVYER
AAIFDGWVDGINAVDASGANCHMSSMGICALLTRMGYATIMQIACRDRNRIAIQGDVLGA
AAMGVGNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDEEKFLSGRRLTTPPAV
FLGAAINPFAPPFDFRPHRLAKKIAAGAQFVQSQYCYDVPMLKEYMKRVRDMGLDEKCFI
LVGVGPLASAKTARWIRSNVPGVHIPDAVIKRLEGAEKQKEEGKRLCIDIINEVKEIEGV
SGIHVMAYRQEEFVAEIVHESGVLKSRKPWKREPGLDDALVAERLDHILHDDPSEKPVEM
VRDASATSSE
>A0A354CFB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium|TrEMBL
MSLQHAPKDIHVSFEFFPPKSEKAEDTLWESVRRLEPVHPKFVSVTYGAGGSTRDRTHRT
VKRMVEETDLTPAAHLTCVSASKDEVMGVVDDYLDAGVRHIVALRGDPPEGMGAKFTPHP
DGFQSSVDLISAIRHYRPELGKRFEISVAAYPEPHPDSLGLAKDLEILKAKQDAGADRAI
TQFFFEPDHYFEFLDAARGYGIDIPIVPGIMLQPNFNGLKRIATLCGASLPAWLHELYEG
LEGDAEQRELITANVAADLTMKLADRGVKDFHFYTLNKAGLSLATCRLLGIKPDKQAA
>A0A8H8V0D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orbilia oligospora|TrEMBL
MERMGSFGPQFIDITWNAGGRLSNLTTEMVNVAQTVYGLETCMHLTCTGMEKEKVDNALQ
EAYNGGCTNILALRGDPPRENEKWSAVPGGFRYAKDLVKHIREKYGDYFDIGVAGYPEGC
DDEVDPDILLDHLKEKIDAGGTFIITQMFYDVDIFLDWVNKVRAKGITVPIIPGIMPIHT
YAAFIRRATWTKIHVPEKWLEVLEPVKNDDVAVRDIGRDLVVELCKKILAAGINQLHFYT
MNLATATRMVLEGLDLMPSLEARELPALPFKSSLGLGRREENVRPIFWKNRHKSYVARTQ
EWDEFPNGRWGDSRSPAFGELDTYGIALKGTTEQNIKLWGRPETVAEIADLFVRYIDGKL
ETIPWSDSPIDASAEPIKAQLSELNKRGFLTTNSQCALNAVKSSHPIHGWGPKNGYVYQK
MYVELLVSPDVLSELITRIERSPDLTYYAVNKAGVLHHNAPAGGSPNAVTWGVFPGKEIV
QPTIVELISFLAWKDELYRLGEDWAACYPQSSASRHIISSVMENWFLVNIVNNNFLDNDS
IFELFKDLKIDNLNEKIPVDEYLQNLKMTDGTNGTAHEATNGAPAA
>I3E8N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus methanolicus (strain MGA3 / ATCC 53907)|TrEMBL
MSFLEKLKNQILIADGAMGTLLYSYGTDCCFEELNLSQAEQITNIHRAYIDAGADVIQTN
TYAANYLKLKRYGLEDFVKEINSAAVKNAKKAAQNRAYILGTIGGNRGIKPNTIPIEEIK
RSFREQLYCLLLEGVDGILLETYYDLQELETVLQIARKETDLPIIAQVSLQEVGIMQDRT
PITEAFNRLEGLGADVIGLNCRLGPHHMLVTLEEVPLPKSAYLSAYPNASLPAYTDGKFH
YEGDADYFRKSARSFREQGVRLLGGCCGTTPEHIRAFAAELHDTPPVTEKAVKQKPKKII
IQPAEAIREYPPLQDIVKERKSIIVELDPPKKLDTTKFFQGAKALKETGIDAITLADNSL
ASPRISNSALGYLTKTQIGMRSIIHITCRDRNIIGLQSHLMGLHTLGLHDILAVTGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNEGLSISGKELGQKAAFSVAAAFNPNVRSLEKAVN
RLEKKMKFGADYFISQPIFSEEKLVEVYEATKHIKAPIYIGIMPLISSKNAEFLHHEVPG
IKITDAIRDRMAKFKDNPHQAILEGLDIAKSLIDAALDLFNGIYLITPFLRYELTVELAE
YARSQSANLVRRNNHVQSIIH
>A0A836NNB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum|TrEMBL
MKFKQAHQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHADHPVYILGTIGGLAGDTDATVQR
ATPATIAASVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFVGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A6L6JQ43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp|TrEMBL
MSKNLTLSCEFFPPKTEKGVANLRRVREALIPLAPEFYSVTFGAGGSTQDNTMEAVLEIQ
EQQPSTGIDAAPHLSCVGSSADRLREMLDIYQQNGIHRIVALRGDLPSGMRDPGDFRYAS
ELVEFIRRETGDYFDIEVAAYPEVHPQAQTAEFDLDNFKRKVDAGANSAITQYFYNIDAY
RFFLDRCVQKGIDIPIIPGIMPINNFAQLARFSASCGAEIPRWLRKRLEEFYDDTESMKA
FSLDFLTEFTRQLIELDVPGLHFYTMNKTEPTLTICQRLNLIKQ
>A0A854QR94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus neoformans var. grubii Tu259-1|TrEMBL
MPHLTSLIAAHNGPFHNYEFFPPLTDPGFVNLLDRIRRLTSPPFQAPLAVSVTWGAGGST
AEKSLELAQQVVGMGVEVILHLTCTNMPKDKVDFALRRCKDLGISNILALRGDPPREEEY
AINPTSTPDFFKHADDLVRYIRQTHGDYFCIGVAGYPNPHPDSESEEEDFKWFKAKCDAG
ADFIVTQLFYDVDVFLEWVKTCRAKGINQPIIPGIMPIQNYASFRRLVNLTKCPVPDSIT
SDLQPISSDDATVKRYGAELATKMVNQIIGSGLVPGVHFCTLNLEKSVRKILDNLGWSAA
SKASENEGVVKNKLIEDDSRAVNGIPINGKADTAQSPAKNLSISPSEANQLAQLGLTSTT
LPPAPKTGLGAQGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKEWGVP
ISTSDLSALFTAYLHSDPKHLTTPFCDLPLSPESHMILPHLLALNSAKVQHWTVGSQPAV
DAARSEDEIVGWGPRGGYVFQKAFVEFFVTENEVNRLKEKVKKEGKGLITMYAANRKGDF
KSNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWTEWSLLYPRNTPSRKL
LEGIANEWWLVSLIHHDYKDQDALWRFLLEDLQ
>A0A0V0PXV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. MKU1|TrEMBL
MTQQRDENPAGAHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYERAAI
FDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIYQISCRDRNRIAIQGDVLGAAAM
GVQNVLCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRSMRDEGTFLSGRKLTTPPAMFLG
AAINPFAPPYDFRPLRLAKKIAAGAQFVQSQYCFDVPMFRGYMARVRDLGLHERCFILCG
VGPLTSARTARWMRANVPGVHIPDAVIARLEGAADQKREGKRLCIDIIDEVKEIAGVAGI
HVMAYRQEEYVAEIVHESGILKGRKPWRPEPRADDALVVGRLDRILHDPRPETPQQILRE
AQAAPQPAKTIP
>A0A1N6M2K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio spartinae|TrEMBL
MGYSYAGHIDALNQNISELSGDLNVSFEFFPPSSPKMEETLWNSVQRLKTLQPKFVSVTY
GANSGERERTHAIIKEIKSRTGLVAAPHLTCIDASREALSQIADDYWNNGIKNIVALRGD
IPPGGGKPEMYAADLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ISQFFFDVECYLRFRDRCVSAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPGWMNQQFD
GLDDDPVTRQLVGASQAIDMVRILCREGVKDFHFYTLNRAEMTYALCHTLGIRP
>S6GUM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CFII64|TrEMBL
MSLDRRYSFEFFPTKTDAGHEKLLNVARQLASYTPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRALLTQYKEAGIKRIVALRGDLPSGMGMASGELRYASDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDIKNFVHKAQAGADSAITQYFFNADSYFY
FVERVRKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EQVITQMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A1H8EY27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmobacter aquatilis|TrEMBL
MTAPRISFEFFPPQTLEASFKLWETVQMLAPLKPTFASVTYGAGGTTRKLTHEAVTTIGK
NYGLNVAAHLTCVDATKSETLSIAEAYADAGVTEIVALRGDAPKSAVRFVPHPLGFANSV
ELIEALAATGKFTLRVGAYPEPHPDAADTLQDVRWLKRKIDAGATSAITQFFFEAETFLR
FRDLCAKEGITAPIIPGILPIDNFVGVKKFATRCGSHVPQWLDEAYTAAKRDGREELLSV
ALCTELCDTLISEGVEDLHFYTLNRPHLTRDVCHALGITPEVALEKVA
>A0A4Y9RP85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas intermedia|TrEMBL
MASLADARALLLSPLGPVARAGSNRDDVRVSFEFFPPKTDEAEANLWKAIRRLEPLNPAF
VSVTYGAGGSTRERTHRTVQRIIAETSLRPAAHLTCVEASREEVDEVIAGYKTIGVDHIV
ALRGDPPGGSGIGGVYQPRSDGYANATELTQAISRAGGFDVTVGAYPERHPESPSIDHDI
DVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLTRMCGA
CGASIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRADLVYAI
CRVLGVREASQ
>A0A3B8MUB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter sp|TrEMBL
MLKNENLCTKLKKRKFVVTAEISTPKGVDITKTIEEARKLKGIVDALNITDCPMANMRMS
PIAVAHLLQDHLNIEAIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDDPSRGDTPQ
AKGVYDVDSIGLLKIISAFNRGYDYNGNKLDSPTEFCAGTTANPNDLRDEALEKLKVKIE
AGAEFIQTQPVYDEEILFKFIEKIKNFNVPLLIGILPLKSYKMAVNLNEKVPGIDIPEKV
LERLKDGGREEGINIAVEFIKRIRSEVAGIHIMPLGSTNVVLEIISRVDDLVCDFAENNV
QMN
>A0A4V5NHP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomyces minteri|TrEMBL
MEKITDKIAALPKDANYFSLEFFPPKTQQGFSNLQARLERMSRGLRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRSLVDDALQQAKALGIRNILALRGDPPRSEE
YRERDDDGVKGEGVSNEEFTWAVDLVRYIRKQYGDHFCIGVAAYPEGHSDQSHPETQDSS
HDLPYLVEKTKAGADFIMTQLFFDVKAYEEYEAMLRNHQSGAFDDIAIIPGLMPIQSYQI
LRRTTKLSHAKLPPDILARLDAVKGDDEAVKRVGVEIISEMVEDIKMTTTRTPRGFHFYT
LNLEKAVAHVIERCQLIPPSSPTINGSDDDTIAVEETGDYLLVDGVAKPKDHRRRMSSAN
NSNPRNRVVVERPSTSSQASFEAPENEAGVPRDKINSRANTLAISEGEGSLGREATWDDF
PNGRWGDARSPAFGEIDGYGVSLHVSIAQAIKLWDHPTTTADISSIFRRHLNGELEAIPW
SEEGLNPETNTIRNELIKLIEKGWWTVASQPAVNGVRSSDSVFGWGPRNGFVFQKPFVEL
FLPSADWERLQRKLADHEEVSYFAGNAAGDFAASNEESVNPVTWGSFAGKEIITPTIIES
VSFLAWRDEAFSTWSEWQRVYPPRSHTARLLDDIKRDYWLVNIIHHGFVEPGALWDLLLE
G
>A0A432RUE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Persephonella sp|TrEMBL
MKIIDKLKETKTSISFEFFPPKTKEGENSLFNTIKELQKLNPTFVSITYGAGGSTRNRTR
NIVKRVFEETNLTVMAHLTCIGHTNSELKDILDDYQKIGIQNILALRGDIPVDKEEDILK
GCKYASELVSFIRKNYKDWFSIGVAVYPEGHPESPNLERDIYYFRKKVEAGADFGITQMF
FDNSYFYRYMELLEKEGVNIPIIPGIMPITNFKQIRKFALMCGATIPESLVKRLEKYEDN
PNDLENVGIEFAIEQCRDLLKNGVKGLHFYTLNKSKATLRIYEAIKDLIS
>A0A354EWB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MASLAEARALLLSPLGPVARAGSNRDSVRVSFEFFPPKSDEAEANLWKAIRRLEPLNPAF
VSVTYGAGGSTRERTHRTVQRIITETRLRPAAHLTCVNASREEVDEVIQGYKTIGVDHIV
ALRGDPPGASGIGGAYQPRADGYANATELTAAISRIGGFDVTVGAYPERHPESPSIDHDI
EVLKAKIDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFNGLRRMCGS
CGASVPDWLAGHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRADLVYAI
CRVLGVRETKVAA
>A0A1Z8LB07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacteraceae bacterium TMED13|TrEMBL
MNNINVSFEFFPPXNXVSIDSLWSNIRRXEPLQPKFISVTYGAGGSTRENTHKLVKEIKK
ETSLTPAAHLTCXXTSVKEIERIADDYWXNNIXHXVALRGDXPKVKQGXNELXFATDLXK
VLKKKFDFEITVSAYPEKHPDSRSIEQEYDILKMKIDLGAXKAITQFFFDINSYFDFLDG
AIKRGISIPIIPGILPVTNCKRTMEFAKKMNCKVPRSXVEMFKGLDSDIETRXLVATTIV
YDXCMKLISSGIKDFXFYTLNRADLSFAICHILGIXILKDDX
>A0A4V3AAR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dankookia rubra|TrEMBL
MDQTFTEPADRRRPEATRGTLQRWLTGPRVDGLPQLAALPAPALSFEFFPPKTDALESQL
WSCIRRLEPLAPRFVSVTYGAGGTTQARTHATLSRIVQETSLTPAAHLTCVGASRGEVDD
VARAYWTAGVRHIVALRGDPPAGAERYEAHPEGYAYAADLVAGLTRVAPFEISVAAYPEV
HPTALSADHDLDNLKRKIDAGATRAITQYFFDSDVFLRFLDRCLAAGITMPIVPGIMPVS
NFTQMKKFSAMCGAGVPDWMGRLFEGLEDDVETRRMVAAVVAAEQVRLLQANGVDEFHFY
TLNRPDLVFAIAHILGARPRAAASPA
>A0A5S3PNI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sabulilitoris|TrEMBL
MTTPAVSFEVFPPQSINASFKLWETAQALAPLAPRFFSVTYGAGGSTRDLTHDAAYTLHQ
SSGLPVAAHLTCVGASRAETLATAQRFAKAGVTDIVALRGDPAKGADSFQPHPDGFANSC
DLIEALARTGQFTLRVGAYPDKHPEAATQADNIDWLKRKIDAGADEAITQFFFEAETFLR
FRDACADAGISAPITPGILPITNWTSARKFAVKCGTDVPLWLDQAFDAAIRDDRHDLLAR
ALCAELCSDLVDEGVENLHFYTLNRPDLTREICHALGVTPQTARIQNVA
>G4QJN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciecola nitratireducens (strain JCM 12485 / KCTC 12276 / FR1064)|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPNSEAMEKTLWKSVERLAPLKPKYMSVTYGA
NSGERDRTHAVVKRIYKETGVSTAPHLTCVDATPTELRQIAKDYWDSGIRRIVALRGDLP
PGVEKTDMYASDLVTLLKDVADFDISVAAYPEKHPEAPNTQFDLLNLKRKAEAGANEAIT
QFFFDTSVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLQRFAGFTNVHVPNWLHKMYDGL
DADDQATRNLMGANIAMDMVKVLAKEGVKHFHFYTLNRCELSYAICHMLGLRSQK
>A0A7X9Q9R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Christensenellaceae bacterium|TrEMBL
MFISDMFKQKSLVYSLEVFPPKKDYSFDQISSVLADICSLKPDYISVTYGAGGSIADNKT
LELCDIVKNGNGVEALAHLTCVSTKKEDIDTLLNQLEAKNIDNILALRGDINPNLPISKD
FKYASDLAAYIKNRGGFGISGACYPEGHFEAPSLVKDIKNLKKKVEAGVSHLNSQMFFDN
EDFYNMLELFELADINVPVQAGIMPVTRKNQITRIIELSGSKLPKKFTRLIARYENDPVS
LMKAGIAYAVEQIIDLIAGGVKGIHLYTMNNPHVAAEITKNIKPFLNNEN
>A0A7X6N220|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Periweissella fabalis|TrEMBL
MGLTELFDKKLVFSLEVFPPHTAVGIEHLQKTLVDLEQIKPDFISVTLGASGITKSEDTI
KVADFIQNDLKIPAVAHVPGLYQSKDEVRRLLDALVAHDVKNVLVLRGDAIKDQIPIGEF
KHADDLAAFIKEYGTFDIAGACYPQVHLESTSTVSDIRYLKRKVAAGVSHLITQVFFDNK
HFYNFKERLELADIDVPVEAGIMPCTNKKQMERIAQITGIKLPKKFVSILSRYENKPLAM
RDAGIAFAVDQIVDLISSGVDGIHLYTMNNADNAKLIWQATHTLFEDATEMKTMS
>A0A365UDB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosalinus halophilus|TrEMBL
MRAETIPAAALVEQPTDALLRRLVESRGAVPLSFEFFPPRSEARRDALRETVDRLAPVAS
EGFSVTMGAGGTTRTGTHDTAVEVARRTGRPVMAHLTALGLSREEALEAADRLWRSGVRR
VLALRGDRPRAVQGPLPPGFAHATDLVAALRARHDWTIAVAAYPEKHPEAGSLDEDIGHL
KEKLDAGASVAFCQFVLDPAAYGRFLEACARRGIEAPIVPGLMPLDGWTRLRGFARANGT
TVPDWLERLFRQGEETPELMPALAATATLEQARRLIAYGAPALHVYSMNRWPLPLALARL
LGHSES
>A0A8E1UHK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae FA6140|TrEMBL
MNYAKEMNALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRSVVDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A7Z2PSU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. CCBAU 051011|TrEMBL
MTDFTPPAFDGHRTLHSPRISFEFFPPKTEEMERSLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTIARILKETSLVPAAHLTCVGAPKGEIDDVVARYHEIGVRHIVALRGDPTTGI
GTAYHAHPDGYQSSPDLIEGIKKRYPDIEISVSAYPEKHPESPTIDADIDTLKAKVDAGA
ARAITQVFFDNDLYFRYLDRVRARGIDIPVVPGIMPMHNFKQARSFVTRAGTTVPDWLAD
KFEGLDDDADTRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A1I1TX50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sp. CF118|TrEMBL
MNSSLRSKILEGNAGLVFYSLTPPKITTEEAKVLTIANNQIERLKNLNIDALILYDIQDE
TLRTEKERTFSFIPTITPELYGRNFISELSIPKIIYKSIANQTREEFENWLKQNEDLEYT
VFVGASSHQQIEATNFSLSDAYNLKKKYSPNTLLGGITIPERHSKKKDEHLRIFNKIEYG
CSFFVSQCVYNINDTKNLLSDYFYNSLERECNIAPIIFTLAPCGSLKTLQFMEWLGIEVP
GWLYNDLKHSKDILEASINTSTNIAIEILNYANKKNIPVGFNVESISIKKEEINAAQEIL
NNILNLLKPGKQLL
>A0A1D7TGB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurospirillum halorespirans DSM 13726|TrEMBL
MIENFIEKLKYDTFLTLETTPMHEPTFEPIIEKIAAFGLDKIVDGFSTTDNPLARLKFNA
LFGALKLQTQFHKPVIATMSMRDRNKVALQSDLLGANGFDLRTILALTGDPASASDQPAV
KGVFEGNSTLLLEIIQCFNAGIDYSGKPFKTQPKPIYSFAVCNAHANTPKNLMKKMATKI
KHGAVGIITQPVYSVENAKMLLDLLKDAKAEINKEQSQAQLILGFFPIIKLRTAQFLSAH
VPGIHVPSIWMDKLAHAKKISEEEEKKVGFELSLNAFLELKKIHPKIHMMSANNFELVAD
LVKY
>A0A2G5L262|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reichenbachiella sp. 5M10|TrEMBL
MKVTEHIKNANGKTLFSLEIIPPKKGENVQTIFNHLDPLMEFNPPFIDVTYHREEYVYKK
HPSGLLEKKTTRKRPGTVGICAAIRHRYDVDPVPHIICGGFSKEETENALIDLDFLGIDN
VLLLRGDAIKSEGKFIPQADGNNYAIDLLHQVDGLNKGVYLDDSLDDPTPTDFCIGVAGY
PEKHFEAPNLQMDLDYLKQKVQAGAEYIVTQMFFDNDKYFDFVASCRAMGINIPIIPGLK
PIATKAQSTILPSIFHIDLPVELSEALQRCKNNQEAKQIGIEWGIKQSKELMERGVPVLH
YYSMGKSTSVQKIAEAVF
>A0A2A6FNJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lumbricidophila eiseniae|TrEMBL
MSESGSTPTTSPTTRAHPHPVKISFELFPPRTDAAALALGRTIDRLSDTDPDFISVTFGA
GGTSRERSLTVLRYILEHTRIDPMAHLTCVGSSRAEATELVQQFLDAGIRSFLALRGDPP
AEHPNGFSLGDLASAAELVHLIRTTHGGELDRLAVAAFPTGHAKSRTVQQDIETLLVKQS
AGATLAITQLFWRADDYHGFVAQAREAGVRIPILPGVMPVTSAARLARLAELTGVEPPVE
LARTLESEPDASRQTEYGVAFSTELVRDVLAGGAPGIHLYTFNRHEAVLDVITRLGLRAG
SLASVT
>A0A1I2CRF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sp. CF118|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYEHLDPLMEFKPAYINVTYHRSEHMFKKK
SDGSFEKVEIRKRPGTVAICAAVMNHYNVDAVPHLICGGFSREETENALIDLNFLGVDNV
LVLRGDAPKNEASFEPEPNGHRYADELLQQVVHMNNGIYLEEDLQGGVKTKFCIGVAGYP
EKHFEAPNMQTDLNYLKRKVENGADYIVTQMFFDNQKFFDFVAKCREAGITVPIIPGLKP
ITTRKQMNILPRTFHVDIPADFSNEILKCKSDKDVEELGAQWLIQQSKELKAFGVPIIHY
YTLGKPNVILKAIQAIS
>A0A6H2DNB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasphingorhabdus halotolerans|TrEMBL
MNAQNKPLGFSELEEAKRALDVPLFAGLSGDADVSFEFFPPKSEKMEQTLWDSVITLEPL
NPRFVSVTYGAGGSTRERTHATVARIAKETNIPAAAHLTCVDASKDEIKEVATAYWEAGV
RHIVALRGDPPSEGQAFEPHPQGYASAAELVAGLKDIAPFEISVAAYPETHPEANCPQTD
LDNLKRKLDAGASRAITQFFFTAEAFFRFRDAAGAAGIDAELVPGILPVSNVAQTRKFAG
MCGAEIPAWMNDLFDGLDDHPSARQLIAATVAAELCRKLYAGGVRQFHFYTLNRAELSYA
ICHLLGKRPEAQSKELSA
>A0A807DQ86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella bronchiseptica|TrEMBL
MTQSTAPAFSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRT
LRNLGCDAAPHLSCIGATRDQLRDILAAYREQGVRRLVALRGDLPSGMGGDAGELRYASD
LVAFIRQETGDWFHIEVAAYPEMHPQAESPSADLAHFVNKVQAGADAAITQYFFNPDAYF
DFVERAQAKGVTIPIVPGIMPITNHTQLVRFSEMCGAEIPRWIRLRLAEYGDDKASIRAF
GLDVVSELCQTLLDNGAPGVHFYTLNHAEATLGIWKALNA
>A0A7R6XRF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 131-2-1|TrEMBL
MSARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDTIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A8B6XIP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydra vulgaris|TrEMBL
MSQGGPLFCDITWHPAGDPSGDKETSSCTIASTASNYCGIETMLHMTCANISCDLVLKNL
KKAKNLGIRNILALRGDPPKGEVWMASDENLRFGADMVKFIRKHFQNYFTICVAGYPQGH
PDCTSYEDDLIHLKEKVDAGADFIITQLFFEPNIFFKFLADCRRIGIDVPIIPGVMPIQA
YASLLQLVKLSKLEVPQYIIDDLEPIKNDDEAIREYGVKLAVSMCRELLSSDDVPGIHVY
TLNREVATTELLQQLGLWRPYQSHRLLPWKPSANLKRLQEDVRPIFWSSRPKSYIHRTSN
WDEFPNGRWGNSSAPSFAELSDHHLFYLKSKESEEERLKMWGEKLDCIEDVYHVFQCYLS
GKKNKWGYKVKSLPLNDDELQPETSLLSDQLYRINGHGFLTTNSQPAVNAALSTDERFGW
GGAGGYIYQKAYLEFFMHKKNVDFLLEVLNDNPRVNYHIIDSHGCYDKTNADRYSPIAVT
WGVFPGKEIIQPTVVDPISFNFWKDEAFSLWIEKWQSLYEPESFSAKIIQSIYNDFYLVN
LVDNDYIKGNCLFDIIDCVIAKSSLE
>A0A3E2V0M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MMNIRELLQTRPLLFDGAMGTYYKAAPGVECEQANLTDPAGVLAVHREYLAAGADAVKTN
TFSLPRLAAAHAPGWEQLAQAGWQLAVQAAEETGAAVFADLGPAPDTEAVPAGQVYTAVA
KQFAALGARNFLFETLSSDAGLLDAVGAIKAEVPDAFVLVSFAVLPDGYTREGMYCKDLA
RRMQESGIVDAVGLNCVSAPGAMRTLAKQLGGTLPLSVMPNAGYPIVTRTQVKYQGRPEY
FARELGRLAAEGTVQILGGCCGTTPAHIAALRAELDSLPVVEKTAPAEEFSTVKEQTVEN
EDAFLRKLNAGEKVIAIELDSPRTADLTGYLEGAKKLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGLCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPGPMTVFGALNLNARNFDVELRRAKEKLENGMSGFL
TQPVLSAQAVENLKKSRETLGVDAKILAGIMPVVSQRNAIFMENEINGIHVEDWIIEKFA
GLDRAQGEELGLAISLEMAKAALPYADGFYLMTPFNRVALMERLIGRLKQEVLGAY
>A0A4Q3BGS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium|TrEMBL
MKITEHIKNAKGKALFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADHSFVPTKGGHCYATDLIEHIKNHNDGKFLHEDIETFKSDFCIGVAGYP
EKHFEAPNLNADFKFLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPDELTDALSHAKSNAEAKEIGTAAMIKQCKELIDFGAPVLHF
YTMGRPEQTKQIAKAIF
>A0A4Q3B3P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium|TrEMBL
MKVTEYLNHRKKTLFSFEILPPLKGKSIQSIYQSIDPLLEFEPAFIDVTYHRQEYIYKKH
DNGLLEKVSVRKRPGTVGICAAIMNKYKIDAVP
>A0A4S4N3T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Antrodiella citrinella|TrEMBL
MKISKKIEQAVKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
DLTSELVRTCQSLIGIETCMHLTCTNMPAEKVDLALKEAKEHGCRNILALRGDPPMGKDE
WEAVEGGFIHGIDLIRHITKNYGDYFDIAVAGFPQQQLLPPDELAQEIQWLKEKIDAGAT
FIFTQMFYDVDVFIAWVKTVRAAGITAPIVPGIAPIQTFNGFIKSTALARTTIPKALMDA
LEPHKNNDEKVREIGTKVVADMCRRILSEDIGIRGLHFYTMNLEKGTRMLLEELNLVPRV
EVVKPLPWRQSLTPNRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWLKQTKEEANKLWGQPTSFAEINALFSRFCRGDLPALPWSDSAPASETTVISESLA
KLNDLGFLTINSQPAVDGCKSEDRVHGWGPAHGYAYLEFFVQPDLLALLLPHVERDPNIT
YYVINKQGDLRTNTLSDGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGRQWGNL
YDSDSPSRKLILDLMENALLVNIVYNDYKQPNAIFEPFLKAGAELSSQRGLKEHTAPTPN
GAAH
>A0A1T0CUH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella pluranimalium|TrEMBL
MPFSFEFFPAKTDEGQDKLLSVFDELNALNPKYFSVTYGAGGSTRERTLGIVEALIKKGD
TPIAPHMSCIGDTKAQIGELLDFYKTLGVDRVVALRGDLPSGQVGYGELPYALDLVKYIR
EHSGEHFAIKVAAYPEMHPQAKNFEADIDNLVAKYHAGANEAITQFFYNPDSYLFLRDRL
AKKGVHQDDFPIIAGIMPITNASNLIRFADGCGADVPRYIRKQLADYGDDKKSIRQFGFD
IVHQLCERLISEGVPSLHFYSMNQTEPNKALVESLGLI
>A0A1V1PFZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Magnetoglobus multicellularis str. Araruama|TrEMBL
MKSGSNLEKILSSGSFAFTGELGPPRGANVEAVRQKAAPLKGMVDSVNITDNQTAMVRMS
SWAASLIAIQEGLEPNYQMVCRDRNRLAMQADILGAYAHGIRNILCLSGDHQQFGDHPNA
KGVFDIDSIQLVNMIKNMRDDGKFMGGADIDTPPGMFIGAAANPFADPFEWRVYRLAKKV
QAGADFVQTQCIYNMKKMREWVKQANDMGLTEKIYILAGVTPMKSLGMARYMKSKVPGMD
VPDEIINRIKGVKKKGQADEGIKIACEQIEEFKEMKGVAGVHLMAIEWEHKVPEIAERAK
VLPRPVFDD
>A0A2E7M0T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacteraceae bacterium|TrEMBL
MSPTMDQMREAQRALEAPLFSGLPGDIDVSFEFFPPKNAAMNETLWQSVETLAPLGPRFA
SVTYGAGGSTRERTHQQVVRIQNEARIPAAAHLTCVEATREEVDEVARHYWDEGIRHIVA
LRGDAPDGQSQYAPHPGGYANAVELIAGLKRVADFEISVAAYPEVHPDSPDRQADLDNLK
AKFDAGATRAITQFFFDPQCFFDFRDRAAAAGIDGEIVPGIMPVLSFAAVRRMSGLCGTA
IPPWMEGLFDGLDDRPAARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRAKAGR
>A0A356B1L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MGSNDMGNKNQISAFKAIVKDHILLTDGAMGTYYVMHHNGKNTPETENIENPGLVRNIHR
EYIKSGAKLLRTNTFAANCRTLDIDHTTLRKIIKAGYKIAVEAAKEKDVFIAADIGPIPE
SVSETPGKAYEKNRLDEYIELLDAFIEEGARIFWFETFGRTEDVEFCAAHLKNVCPDSFV
IAQYAFDDTGFTREGISLSTVCSKMIENRDIHAWGFNCAMGPLHMLSLIEHLPVEKKFCL
SALPNAGYPQIENQRTVYPGNPEYFADLVMKMVEAGARIVGGCCGTTPEHIQAISHRLFE
AKYKISPKTKEKKKTVGWMPAVANPFKEQMDKGKKAIMVELDPPFSSDTVQILQSVEYIK
DCADVITIADSPLGKVRADSLVIAAQIKRKTEVETLPHLCCRDKNIIGLKAGILGAHAEG
IRNILVVTGDPLPGNERTSAKSVFNLNSKGLIGLINDLNKEIFVNSEINIGAAINPNVPN
FDAQLKRTEEKVKAGASFFLSQPVYSEWAVKNLSRIKKELGVKVIAGIMPLASYNNAIFL
NNEVPGIVIPDEYVNRFHKDMDKEEAYRTGVAIALECMEIAKDLDGYYFMPPFNRVTMIA
EIIKEMKNNEQR
>A0A846F175|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO1H5|TrEMBL
MNRFRNAVKSGEFLVTAEVAPPKGADPAHMIEMASTLKGRVHAVNVTDGSRAVLRMSSLA
ASIILKNNGIDPICQVACRDRNRIGLQADLMGASALGLHNILALTGDPVKAGDHKDARSV
FDMESVRLLQMIAKLNQGIDWNEKTLPDGATDLFVGAAVDPQSPSWSGLKKRFERKLLAG
CQFFQSQLISDFDKLEKFMNQIAVESNKPILAGIFLLKSAKNAAFINKYVPGVDIPEHII
NRLAKAEKPLEEGIKIAAEQVQIASKICHGVHLMAIKREDLIPRILDMAEISPIEQ
>A0A8H6EYT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dekkera bruxellensis|TrEMBL
MKVTQKLEGAHNDERSPASFSFEFFTPKTSQGVQNLYDRMDRMYNLNPLFIDITWNAGGR
LGTLTAEMVNVTTTVLGLETCMHLTCTNMGLEKIDAALDSAYKCGCENILALRGDPPLDG
SESTGVFRYAKDLIKHIKSKYGDHFCIGIAAYPEGHPEEHDISKTIKYLKEKQDAGGDFI
MTQMFYDVDIFIEWCKKCRASGITIPIIPGIMPISTYASFLRRAQWCEIHVPDHFLKRLE
PIKEDDSKVREEGVKLVAEMCRKLLESGYINHLHFYTMNLEKSTVMLLKQLGLVSKQQVV
GMDTKPWRRSLNPTRSDENVRPIFWQNRKFSYIQRTADWDEFPNGRWGDSRSPAFGSIEL
CDHELIRHSELSSLIIKYLQGKLSCLPWSDGKVTSEIDLIKDALIDLNSRGVITINSQPS
INCCPSADKVHGWGPKNGFVYQKQYLEFLVPTTSVNFITNKINETNRDAGYSVLSYYSIN
SRGLLCSNVQSSSAINAVTWGCFPGEEITQPTIVEKISFIAWKDEFFSILKKWISLFKKD
HDVEGGKSIALIEMLIRDYTLMNIVDNDYVAEPNTRIFFCPQGHFPTKAIIKGNLLEC
>A0A0H4PDZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus smithii|TrEMBL
MGFLDRLKTEILTADGAMGTLLYSYGIDYCYEELNIAKPEIISKIHEEYILAGADVIQTN
TYSANAVKLRRYGLEENVKQINKAAVRLAKQAAADHGTFVFGTIGGIRGFRKDTCSLADI
KEAFLEQAESLLNENPDGLLLETYYDFEELTTVLKIARKLTNIPIIAQVSMHEPGVLQNG
LSLNEALHRLEDHGADLVGVNCRLGPYHMIQALEKATLPKKAYLSAYPNASLLDVKDGRV
IYESEAEYFGRAAVKLRNQGVRLIGGCCGTTPKHIEAVKKALSGLSPIHQKSVKPEKPII
VKEPPAPLDPPLHELAKKKRTIIVELDTPKHLDTFQYFQGTQVLKEVGIDAITMADNSLA
SPRISNMAMAALVKANQRIRPLVHITCRDRNLIGLQSHLMGLHTLGIHDILVITGDPTKV
GDFPGATSVYDVSSLELISLIKQLNNGISFSGKPLKQKTHFSVSAAFNTNVRVLEKAVKR
MERKIECGADSFITQPVFTKEKIKEIYEATKHLNVPIFIGIMPLTSLKNAEFLHNEVPGI
KLSDEIIERMRAFDGDKEKSQQTGIEIAKELIDTALRYFNGIYLITPFLRYEMTADLARY
IREQDAKKGETVHAEITTSN
>A0A358QTZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotomaculum sp|TrEMBL
MKYLSKLHKILDSGQFAVTAEIGPPKHASVEGVKHHAHMMKDYVDATNITDCQTAIVRIS
SIATGVHVLGAGIEPIVQMTCRDRNRIAMQADILGAYCLGMRNMLCLSGDHQKFGNHPTS
KNVYDVDSMQLIQALRRMRDDKVFFSGEEIKECEPRFFIGAVANPFADPFEYRIDRLEKK
VEAGAQFIQTQCIFDMERFERFMEKVRERGIDQRVHILAGLTPLKSWRGAKYMQSNVSGM
IVPDSIVERLKSAEDPKKEGVDLCIEQIKYVREKIKGVHGVHVMAIAWEEIVPEIVERSG
LYPRPQVDPSELE
>A0A4V2HS97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda hymeniacidonis|TrEMBL
MKVTEHIKNAKGETLFSFEIIPPVKGKSIQELYDNIDPLMEFEPPFIDVTTSREEYVYID
RDGLFDKRLTRMRPGTLGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEQYFEPTNGGHKYASDLVKQIQGLNRGEYLHEVIETDNCADFCVGVAGYP
EKHMEAPSLNSDLKRLKEKVDLGAEYVVTQMFFDNKKYFDFVQAARDMGIKVPIIPGIKP
IAVKRHLQLLPQVFRVDIPEELIEAVEGCKNNKEVRQVGIEWCIEQSKELKAGGVPVLHY
YSMGKSDNIKAIAKEVF
>A0A3R9QPU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Korarchaeum cryptofilum|TrEMBL
MEIGIEIVPSNLPKFLRSLSSVIGHANFISLPECPFGRPLPSPLILSVVAKGLGLEVIPN
YRVMDRSELGFISEIMALSEVGIRRVVIVRGDLPSIGMPTSLNPVRAIELIKEHGIDIEV
GVATYTKPNEALRAKIEAGADFVVTQPIQDVGELSELLDFLGDIPLYTMIMPGMEDLDLN
VLREMGLNEVRNVDYKALLQDISRTKVRGVIISSPKGVSKALEILR
>A0A358UB96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp|TrEMBL
MLNKFKESILDKNTLSVTWELVPGRGANEKAQESAIASAEQAAKGGRVHALTITDNPGGN
PAILADYLGMEILKMGIEPLVHFTCKDKNRNQMESQLYALDRAKVRNLLVMTGDYTYSGF
KGRPKPVFDLDPSNTLQLIAEMNKGLEVQGMKGPTYHAPSDFFAGAAVSPFKSTEAELMV
QYYKLKKKIEGGAQFVVTQLGYDARKCHEVIQFLKVNKLDIPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNEEKGAADKGVGQRMLRAAKLYAILKGIGCAGVHIGGHNLKYEQ
LEYILDKGEELYPNWQDLVKEFDYPQTNGFYYFEKDEKTGLNTDRPTNRANLPLDAPAGA
MYSLMRGMHGLMFTPDKKLFPMMRSMYRAAEGKKKTEKRLHAVEHLAKVVMLDCKDCGDC
AMLDLAYLCPMSQCPKNQRNGACGGSLDGWCEVYPKEKKCVWVRAYARLKKYGEEASLDV
PPVPPANWDFYQTSSWSNFFLGKDHSAPILGIKRPESKLKK
>A0A6I2JM91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. RIT698|TrEMBL
MSQLSQYFAQNQFCCLVEYLPSKQEVLPVATQLAGFPVCMTLSDRVRSDEDIAPLIAAQS
YPQQIEKVLHYAGKGRDIHDFNLFLTQAKQHGQQNLLLLTGDKLKQHHDGQGSHARTRYL
ESVNAVIAAKQQGGFHIGVALNPFKYSQAEKQAQYLKLHKKLQAGADYIITQLGFDLVAL
KQAHEFLIEENYTQKILACVMPLTLARAKFMLKHNVAGIVITPHMLEVLAQEHDSDQTEN
TYLRCALQILICQHIGYAGVHLSACHKADEQAILTSYIEQYRHLDLKQCEQLWTQLWQLK
TGNELRPAAVEKSKLRNLHQKVKYQFLDTIHSTMFNSSLVKGLGAYIFSANFWNKALAAK
LLLQAEYLSKHFIVGCESCGQCRLAETLYICPETCPKGLANGPCGGTHLDRCEFGDRECI
HSIKARLAEEVDQIQILKKQLIPTVPIEVRGTSSWKNWYVKQ
>A0A356PDC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp|TrEMBL
MENKFKESLLNKNTLSVTWELVPGRGATEKAQETAIASAQQAANGGRVHALTITDNPGGN
PAILADYLGMEILKMGIEPLVHFTCKDKNRNQMESQLYALDRAKVRNLLVMTGDYTVSGF
QGRPKPVFDLDPSNTLQLIEAMNKGLEIPGFKASTFNAPSDFFAGCAVSPFKSTEAELMV
QYYKLKKKIQGGAKFVVTQLGYDVRKCHEVLQFLKINKLDIPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNLEKSAPDKGVGQRLLRAAKLYAILKGIGVAGVHIGGHNLKYEQ
LEYILDKGEELFPKWKDLVKEFDYPQTNGFYYFEKDERTGLNTDQPTNRDNLPLDAPAGA
MNSLMRGMHGLLFTPNKKLFPMMRGMYRATEGKKKTGKALHAVEHLAKVIMLDCKDCGDC
AMLDLAYLCPMSQCPKNQRNGACGGSLDGWCEVYPKEKKCVWVRAYARLKKYGEETALDV
PPVPPANWDFYQTSSWSNFFLGKDHSAPILGIKRPESKIPKS
>A0A3D0Z2P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MSAERSRLERLLEQGHFAVTGEVGPPQGAGAEGIRHHTALLKGVTDGQNLTDNQTAIVRL
SSIAAAVHVLAAGGEPIIQMTCRDRNRIAIQSDLLGAYSLGARNLLCLTGDHQSFGNHAA
ARNVFDLDSVQLVKLARDLGEPGVFQNGEAIAVEHRARFFVGAAENPFAEPFAFRVRRLA
KKVAAGARFIQTQAIFDLPRFARWMEMVRDAGLDRETYILGGICPAKSFGALRHMSTVPG
MVVPEPLLARMKGVERKKQAEEGVKIAVEAIQELRRTPGVAGVHIMAIMWEEMVPRIVEE
AGLLPRPA
>A0A3D4LGT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
FEIFPPKPDYPIDTIFNTIDELYSLEPDFMSVTYGAGGSTKDRTVEISSYIQNKYNLTSN
AHVTCISSSKEEVQNISKSLKEKNIQNVMALRGDYPKDNLSGLPVDRYNNSVELIEYFKQ
NTDFCIGAACYPEKHPDAKDLNADIDFLKRKMDAGADYLVTQLFFDNGMFYDFYDKAIKK
GIYLPISVGIMPILNKRQITSIVRLTGNSIPNKFRRLLDKYENNPEALKEAGMSYAVSQI
IDLLSWGVDGIHIYTMNKPSTARKILENISAIR
>A0A3D1LEM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MSRLKEALETGKFGVTAEMAPPKGYDFTEQLEAGKLLAPKVHAVNVTDMQSASLKASSLG
LCIALKNAGVEPILQMTGRDRNRMAIMADVLSAASFGIDSVLALTGDHPVVGDCKDAKPV
YDLDSVGILNMLSKMEQTNCDCGGNEIAGGAPKLYKGASVTPVYEPVFLQINKLRQKVEA
GASFVQTQGIFDLDAFKRFLEQVDAAGIKTHVMAGIIPLKSAGMARYMNENVPGIAVPQE
MIDRLAAAAEEGKAKGVKGLPMKLGMEMAAEMIAKIKDEHLCDGVHIMAIGAEKNVPAIL
DLAGITI
>A0A0T6A5F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division NC10 bacterium CSP1-5|TrEMBL
MKRIRDLFHHQEKTYSFELFPPKTDKGFENLLKTIAQLCELKPDYISCTYGAGGGNREKT
FDVVQHIEARHQVIGMAHLTCVLNTKDDIGAIVENIKSRGIRNILALRGDPPKDQPDWQP
TEDNFKYSSELAAFIRAQYGDYFGITVAGFPEGHLLCPDRDKDAEFLKLKIDAGADFVIT
QLFFDNRDYFAYIERLRKIGVEVRVIPGILPITDYKALQRFCAVCGATVTDEVKRMFEPL
QDDQDATVQAGTEFAIRQCQELLRGGAPGIHFYCLNKVHPTADILEAVR
>A0A2V2DW60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKLSDFLKKENLALSFEVFPPKTDTAFESVKAAIEEIAALRPAFMSVTYGAGGGTSKYTL
EIAEDVKKRFGVPSLAHLTCVSSTKDTVRSRIENIKRAGIQNVMALRGDLTPELASADRS
NWPYRYAVDLVRELKASEADFCIGGACYPEIHLESRNQEEDIRHLKEKVDAGCDFLVTQM
FFDNNLLYNFLYKIREAGITVPVIPGIMPITNAKQVAQAIKLSGSFMPQRFKSLVDKFGG
SPAAMKQAGIAYATDQIIDLYANGIKNVHVYTMNKPDVAGKIKSNLSDILSRP
>A0A0S8K0L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. SM23_62|TrEMBL
MKVIDRIRNTKETLFSFELLPPVKGHSIERLYNAIDPLMPFNPLNINITYHQQEVVYKKI
DHKLMEKKVVRKRPGTVAISAAIKYRYKITVVPHLICGGFTREDTEDALIDLHFLGMNNL
LVLRGDPPRGEKRFIPEEDGHAHAIDLVRQIMNMNKGIYLEEGLKNATPTDFSVGVAGYP
EKHFEAPNMQTDLHYLKAKVNAGADYIVTQMFFDNQKFFDFVAACRNIGITVPIIPGIKP
ITYLNDLNLLPQTFSVDIPQDLVCEVKKCKTNAEARQVGVEWTAEQSRELKAAGVPVIHY
YTIGVSDNIQQIAKRVF
>A0A1J5EP35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium CG2_30_60_27|TrEMBL
MLVRDILKQEKLSFSFEFFPPKEEAQWEKLFQAIADLMPLKPSYVSVTYGAGGSTRDRTH
NLVVRIQQETDITVVSHLTCVGSSREEMLAILRKYDASGVHNILALRGDPPRGVTNFQQP
ADGFGHAAELVAFIKQHFPHFCVGVAGFPEGHPETPNRLREIDHLKAKVEAGADFIVSQL
FFDNRDFHDFRARCELADIKAPIIAGIMPITSRNGMMRMADLAAGARVPARLLRAIERAG
SDELIQKVGVHWATEQVRDLIDHGVRGIHFYTLNNSRETLKIYEALGVRDSRQLSA
>A0A356WEA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobium sp|TrEMBL
MSIFSRLKKSSVKVTPAVKELVGNMRYELIPMKSIEQGILDLPNGAPVSVTCSPAKGIAA
TQEISARLIAAGHEVVPHFAARLVESREHVTKLASWVREQGIKEVFLIAGDAEKPAGPYK
DGVELLRDFLDSNSGVDRVGFGSYPDGHAFISREDLSTALHHKQKLLEEAGVQGLASTQM
CFDIALIRSWLEQERNNGFKMPIQLGVPGVVDRTRLMTLGVRVGVGQSMRYLSKNKTSII
KMLSPGGYDPTELVAGLAKDAKRLNIIGLHSFTFNSVADTAVWQREVMGS
>A0A524PI24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidia bacterium|TrEMBL
MRVIDKINSAKRPLFTFELLPPLKGHSIDRIYVAIDRLIEFEPAYINFTSHRNEVEYRER
PDGLAERYTVRKRPGTIALAAAVKYKYNITVVPHLLVGGFTKEETENAMIEMNFLGIHDL
LALRGDPPRGSRMFMPEEGGHMYASDLVGQIAG
>A0A1G4M9R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea fermentati|TrEMBL
MRISHKLQRHRESEDSTKPTFSFEFFVPKTSQGVQNLYDRMDRMYQTHPQFIDITWNAGG
RLSQLSTDLVSTSQSVLGLETCMHLTCTNMPVELIDEALEKAYVSGCQNILALRGDAPIN
AGEWKPCDGGFSYAKDLVRYIRKKYGDHFDIGVAAYPEGHPEESGDDMLIEYLKEKIDCG
ADFIVTQMFYDADIFIDWCRRVREAGINVPIIPGIMPITSFASFMRRADWCQIHIPEEFL
AKLEPVKDDDQLVRDIGTELISGMCQKLLDSGYVTHLHLYTMNLEKASIMILDRLGLLPD
ESDNVQDNVMPLPWRKSLHPKRRNETVRPIFWQRRPYSYVARTSQWSADEFPNGRFGDSS
SPAFGDLDLCGSTLIRQSGKRSLELWSTPTSLKDISNLVIDYLHGKLKCLPWSDVPLNHE
VDPILPDLIELNENLIITVNSQPRINGAKSSDRVIGWGPSNGYIYQKQYLEFLLPKSKLD
QFLSIVGDGTTLTYFAVDSANKVFSNHPDDAAANAVTWGIFPGREILQPTIVEKVSFLAW
KEEFYHILDEWKLNFAENGKPESVKLLQTLIDDYLLVNIVDNDYVSPDNTIHDLLRKLY
>A0A315Z7E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sediminitomix flava|TrEMBL
MFKEIIKTKKTGFITYGITPPKQRNAPEKLTEISQNQIRRIKELDIDALVIYDIQDESDR
TSEERPFPFLPSLDSMEYSDSYLDELDVPKIVYRCVGKYSQEELANELSNKDSNSCMVFV
GAASSKQQVMMTLGDAYSLYQNTPNNTKLGGVCIPERHQTKKDEHLRMIEKAKKGCSFFI
TQTVYDVSAAKDFLSDYYYHCQKENIEMQPIIFTLAPCGSLKTMEFMKWLGVSFPTWIEN
ELANSVDILHHSVDYCVDIFKDLYSYAHLKHIPVGFNIESVSIRKKEIDASVELLKRIRE
EL
>A0A317VLK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus eucalypticola (strain CBS 122712 / IBT 29274)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDVQDPARDLPYL
IEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPQVLSKLEEVKHDDDAVKRIGVDIITDLVHGIRDLVSPGLRGFHFYTLNLEKT
VSFILERCELIPPYTEIDDSDALVDGGNLSAMDSSSYIAPNGTPIRTLASRRSSVSSIPH
NRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEEDSNGLNAETAVIQPELLTLIDKKGWWTLASQPALNGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPSKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNPDDPDPIDIN
PANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDETK
NDVWLVCVVGQEFGAGTEAGSEEEEDEKKWMWRELANSQ
>I0TC95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. oral taxon 306 str. F0472|TrEMBL
MHNQFIDIEQLLRDQSGEKHFSFEVLPPLKGNGTESLFSNIAKLKEFNPSFINITTHHSE
YVYHEREDGLIERQRIRRRPGTVAIAAAIQQRYEIPVIPHVICSGATKEDIEYELLDLQF
LGVNHLLLLRGDKAREDRMFTPTENGHSHTTELIEQVNLFNKGVFIDGSEMKNPGAPFTY
GVACYPEKHEEAPNIEEDLRYLKQKQELGATFAVTQLFYDNKKFFDFVERARSIGITIPI
VPGIKPFAKLSQLTMVPKTFHCDIPEELASLAKECKTDEEARQLGIEWATQQVKELYAHG
FNNVHFYTVSAVKSVHEVVSRLL
>A0A5C5WYH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubripirellula amarantea|TrEMBL
MIPYDETENHRMSLASHYQDGSCAISFELFPPRTEKGMEALCENVRRLTQFMPAYFTCTY
GAGGSSQGTTLEVLRKVREITGLPVASHLTCVGATAEDLEDYLAQATQTGVEYIVALRGD
PPKGESAFKMTDGGFRYANELVEMIRSKFSNLGIAVAGYPEVHQEAVDAQTDLDNLKRKV
DAGGDIIITQLFYDNADFYRFRDKCVAAGINVPIVPGILPVTNFAQADRIASMCKARIPN
ELREAMTESEDDKFQFEVGVQHARMQTADLLENDVPGIHYYVLNKSDAAEALLDGMQLGS
A
>A0A6I6S388|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. GS7|TrEMBL
MALGTASTRTDHARTVRELLASGKRSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWIKHPEGVSYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVA
KCRAGADFAITQMFFYPEDYLRLRDRVGAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAARILAVKDDPAAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQRP
>C2X2K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus Rock4-18|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTNRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQVALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6P1M624|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tichowtungia aerotolerans|TrEMBL
MNIAQQLNASARPLISVEFFPPKTGTGLAGFDLAAQELTGLNPDFVSVTCGAGGSAAGPT
LDICRQLDGLGYKSVVPHCTCVGMSRADLEQTSDAIVAQGLTHIMALRGDPPKGQTHFTP
AADGFRYASELVAFLKERHPGLCLGVAGYPEKHPEAPSIEEDIRHLKEKVDAGADFITTQ
LFLDNDVYFDFVARCRAEGITIPILPGLLPVTSLEQINRMRAFCDFHVPEKLKHDLDAAQ
DRPAKAERIGLYWAIEQISELIEGGAPGIHLYLLNKSRTAFYPELFACLSRVRGQ
>A0A6B1FP09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MASDETPSTRTRAALRELALGASVEILPGQLPSPEVLASHLPRATSVYIPYPPKGRWPDT
VAACEQALAAGMKPVPHLPARSVRSAGELDDWLASVVETGVDAVMLMAGDRATPAGPYPD
TPALLNSGLLAEHGLRRLGVTSYPEGHPLIARADLDEALRRKREYARATGSELWIVTQFV
FSPSPVLAWLARMRDAGCTVPVRIGMPGPVALRALIGYAVRSGVVASARALKRKPGIARL
AGRWSPTPIALALARHLADREDTASLDIHLFTFGGFADAAEWLSNLRKPDELAVCPPETS
>A0A5S9U889|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum maritimum|TrEMBL
MKVTDHIKKANGKTLFSFEIVPPVKGKNIQELYQNIDPLMEFSPPFIDVTTSREEYIYIK
KKELFDRKTTRMRPGTLGICAAIKHKYDVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMNHQKYFEATHGGHLYAKNLVDQIQNLNQGNYLHGITEADHKSDFCIGVAGYP
EKHIEAPSLNSDLKRLKEKVDAGANYVVTQMFFDNKKYFNFISAAKKAGINIPIIPGIKP
IAVKRHLQLLPQVFKIDLPETLIDAVEKCKNNKEVRQIGIEWAIHQSKELLKSNVPVLHY
YSMGKSTNIKAIAKEIF
>A0A151YUR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lactucae|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHELAGFPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFECFLKQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGAAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKNHYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHIGFAGIHLSACHKPEEQMLLESYVEQYRHLELKVLEELWNSLWQVT
TGKEFSPEITRFSRQPTSKQIIKYRQLHVMHEAMFGSKIAKGLGRFIFKASFWENAVVAK
VLIKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVAQTEILKEKLIPTVQLETRGTSSWKNWYLATEA
>A0A1V6DG52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium ADurb.Bin120|TrEMBL
MANPKYGNIFTIMPILTPSRRWQPPFYPFKKRSFSERLEEALERSFKGLIWGCRMCGNCL
LQETAFICPMACPKGYRNGPCGGSTPESCCVDESRPCIWHAIYVRAEKMNRLEKLLEVFP
PLDWDKAGTSALRDVYNKINSHGKLRTISTIFRSSTTERKSKWERFFKDIRQPAWWDGDA
YPHPPKPHEPVSSLEKLLSEGKFVLTCEIVPPAEDNFPVLDAKLAELSGLVDAVNITDNA
SAIPRLSAFACAQQALTSGIEPVLQMTTRDRNRLSLQASLIGASAAGIRNLLLVTGDHPI
KAIAPFSHMDAWDLDSIQAVWIARKLRDEGVFLDGRTMDHPPSYFLGSAAAPFASEPRFQ
ALRAEKKINAGTQFIQTNLIFDLPRFEAYLEELEKRNLLSRVHLIAGVAPIKSLAAAKYL
RQLPGVVIPDDIMQRLADAKNTSTEALKICLELIEKLRALPGIRGLHFMAVPNTDHLKKV
LIESGLRE
>A0A2A7WR86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS002410|TrEMBL
MGLLEKLSNGIVLGDGAMGTLLYSGGLHSCFEELNITERDRIIHIHEQYIDAGAEVIQTN
SYGANAGKLRQYGLEKLVKQINQMAVRNARAASKGRALVIGGIGGMKYVGSTFTTPLERE
MMLLEQASALLEEGVDGIMLETFYDENELYDAVNLLRGRTDLPIISQVTLQEIGIMQSGQ
YIEKILPRLVDLGADVVGINCHLGPLHMLESLNTVSLPTNGYLSAFPNSGLPLYAEGKYE
YKSNPEYFEDMAKPFIEQGVRLIGGCCGTTPAHIAALRKKIDTLQPVTKKEVKSRTIKIT
IPKQVEQKDETLPEKAKQKTTIIAELDPPKTLQTRKFFEGARALHSAGADAITLADNPLA
SPRISNVAMASLLQRLDVPVLTHLTCRDRNMIGLQSHLMGLSTLGLNEILAITGDPARVG
DFPGATSVYDVASLDLIRMIKEMNEGRLYSGKSLGNGTRFSVAAAFNPNIRKFDAAIKRL
EKKVEAGADYFLTQPIYDFETIDKLYEATRHIKQPIFIGIMPLVSKRNADFIHYEVPGIT
LSDEVRNRISSVEPEKAIDEGKKIAKELINYAKDKFNGIYLITPFLKYEITEDLIHFTKS
SNKEGIQL
>A0A2E6PFU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MELNPTPIFSIEFYPPRTNADESKLNAVHQQLAKLRPDFFSVTYGAGGSTKEGTKQIVLR
YQQFGSNMAPHLSFGGTDQDEIKILLAAYKAAGINRLVALRGDSPSGGSAITHHRYASEL
VEFIRLETGEYFHIDVACYPEPHPDSKNYQSNVRYFKQKIDAGANSAITQYFYNADAYFY
FVEYCYKAGISIPIVPGIMPITNYANLARFSAKCGAEIPYWLQKRLEGFGNDVAGLREFG
IEVVTVMCERLLAGGAPGLHFYSMNLAKSVTQIWTNLALSDRH
>A0A3D5FGF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MHLDDQAVPSTALSVQPGYSSSGRLERVLRAGSFAVTTEIAPPDSADSAEVYRRAGIFDG
WVDAINATDGSGANCHMSSVGVCSLLTRKGYATVMQVSCRDRNRIAIQGDVLGAAAMGVS
SILCLTGDGVQAGDQPDAKPVFDFDCMSLLQTVAAMRDRS
>A0A2D5T9X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSHANDTATRPSLSFEFFPPKDDAGIDRLMSGTASRLSAFDPEYFSVTSGAGGSTREGTQ
ALVEKLVRSGANAVPHLSVGGSTDAEVGRLVEHYRNLGIQRILCLRGDQPSDGNQHTVFA
RDLVERLHQRFPGQFELSVAAYPEIHPDSASAEEDMRYFAAKVHAGASSAITQYFYSPDA
YEYFMERCEKAGVHIPVHVGVMPITNIDSLQRFSAKAGADIPRWLSKSMAGYADDEKGLV
SFGVEVVTNLCEKLLTMGAPGLHFYTLNRWGASSQICRNLGFPEH
>A0A127QRJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas pratensis|TrEMBL
MESMKARGLEQLLLLSGDRLPGHHPDQAPVRYLESVPALQIAREHCPDWLLGAALNPFKY
REEEGGAQYLKGQKKLLAGADFFTLQLGFDTAKHIEAQTWMRAQVRMKPMLACVMRLSDK
RAAVLQTVPGIVITESMRELLGREQQVSQAYASARSLERLALQIVGLQLMGYAGVHVCGV
HTLDELLSLEQAIAEQRESMSSLTDWIERWHASWQMLGAPEVCFVPAIGAWEMGQSNVAA
TPRERLRYALLSTVHGQFFSRTGWLSRTLGWSMRRPIWKVGVAADALHAVERTVKRPLVG
CDTCGSCRLQETLYVCPETCPKGLANGPCGGTQLNRCEFADRECVHSVKYRIAKSANQLP
VLAQTLIPCIEAGNRHRSSWPEWFEPKDSTPGR
>A0A523LN35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MRLSFEFFPPRTREGENSLGKVAAKLNEFKPDFFSCTYGAGGSTRVGTHEVVARLGALGI
SCAPHLSIGGDTQTEINHLLDDYGTLGVRRIVALRGDLPSGMARTRVTNNAETLVGWIRE
HSGNQFHLEVAAYPEVHPDAKSPKEDLVYFKRKVDAGANSAITQYFYNVHAYFDFVDRCE
RANLSIPIIPGIMPLTNYEGIVRFSQNCGADIPRWIEKQLEAWRDDVKSLREFGVDVVTR
LCEDLLAANVPGLHFYTLNRWGISSKICRNLGLGNLDSPGA
>A0A3D0ZV48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MRWIRQTYSFRLSSASLLSTDLFLLPVLLVQRFREALSQETFVLTAELPLSPKLNRHAIV
SMAEKLSLSVTAIQIPDHTNARPHISNLTASALLLQAGIDPIMHMNSRDRNRISLQSDLL
SAQALGITSILLMRGMDLPSDHRPRATSIFDVGAIDFITTASAIRDGEALSSARDEHVSP
FQIGAIAQVFDPAPDWTPEKLKAKTDAGANFIQLPLCMNLEILTRYMQKLISARLLWKAS
VMVTIAPFADREAAEKTKASLPDSLIPQSILNQLEQSANPRQTGIDICAEMLTAISKIPG
ISGANILVDEDVSAAAEVVTAFQAAQPS
>A0A432EYD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
SSSFVVTSELTPPKGTDLDELFAKADLLRDLVTAFNLTESHAARMAMDPVAVGHLLIDRG
IEPIVQMTSRDKNRLAIQASILGAAALGVSNVVFMGGDPPKNGDHPDAKPVFDLFASQLL
EAACALNNGTDLSGNALKGTPQLTIGAVANPGASDLALEIDNMKRKADAGAEFFQTQAIY
DVAAFDRFMTKAKPEKPVLAGIIPIKSVKMAQYMNDKIPGVDIPQDLIDKIDAAGDDKAK
VADISIVIASNTVRELRDMTRGVHVMAIGWEDKIPAILDRASA
>A0A2E7U621|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGPQFNTPVSFEFFPPRDESGRDKLAAGTAEKLAALQPRYFSVTYGAGGSTKEGTKXTVT
DLTKRGWQAVPHLSVGAADQAEVLDLVNYYKTLGVKKILCLRGDQTESESQNPQYAEDLV
RLIRQHFGDHFEVVVGAYPEVHPDSSSSQEDLAFFKRKVDAGADVAITQYFXNIEAYEYF
VQQCQNLGIDIPIIPGVMPITNYASLCRFSEKAGADIPRWLDRAMAQHQDSEHDLSKFGV
EVVTRLCERLIDLGAPALHFYTLNRWGAATKICANLGLTAS
>A0A356QZE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MHSVASDPGQALPILEGHVSAGRLERVLRSGKFAVTAEIAPPDAADAGAVYQRASVFDGC
VDAINATDGSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVTN
ILCLTGDGVQAGDQPDAKPVFDFDCISLLQTVTAMRDQGEFLSGRKLTTPPRVFLGAAAN
PFGPPLDYRPIRLEKKINAGAQFVQTQYCFDLVRLREYMSRVRDMGLTERCYILTGVGPM
PSARTAAWIRDNVPGVHIPDAVIKRLLGAENQKEEGVRICVEMIQAVREIEGVHGVHIMA
YKQEERVRDIVEESGVLEGRIPWYPGVSNDQQGQQN
>A0A3C0CL34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTPVSFEFFPPRDTAGREKLTTGTATKLAALGPEYFSVTYGAGGSTKEGTKQTVTDLINR
GWNAVPHLSVGGTDQQSTLDLVAFYKELGVKKILCLRGDQAESDAHNPQYAEDLVRLIRQ
HFGDRFEIVVGAYPEVHPDSASSQDDLMFFKRKVDAGADVAITQYFYNIEAYEHFVNQCQ
SLGIDIPIVPGVMPITNYASLRRFSEKAGADIPRWLDKAMAQHQDSDEELGKFGVEVVTR
LCERLIELGAPALHFYTLNRWGATTKVCTNLGLNVS
>A0A2E2WUA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKVIEHINKSADTQFSYEIIPPLRGKGIQIIIDMIEDLKKFNPPFIDVTSHSSSTQKFGN
GQTVLKRKRPGTISICGIIQNRFNIDTVAHLVCNGFTKEETEDALIELSFLGIKNILAIS
GDGNPKKVIQDGKSINNNSLDLIHQINNLSNGKYLHEIANSSAIDMCVGIGCYPEKHAFS
NNFDHEIDLLKQKIAAGASYAVTQMFFDNSKYFAFVERCRKENITIPIIPGIKILDKPRQ
IDILPKLFNIELPDELHGEAIENIEHIQEIGTSWAIRQSEELINAGAPIIHYYLMNDTSC
MLNILNHLHK
>A0A3D0STA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPSGMRDPGEFRYANELVSFIRSEFGDHFHLEVAAYPEYHPQAPNPNQDLENFQRKVDAG
ANSAITQYF
>A0A525C2Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNLQDNAQNISFEFFPPRTAEGAEKLVEVRNELSALMPEYFSVTFGAGGTTRDNTFDTVI
SIQKDSGFDAAPHLSCIGATADSILQILNEYRDNGVNRVVALRGDLPSGMRDIGEFQYAN
ELVEFIRKETGDYFHIEVACYPEFHPQARSAKDDLLNFKNKVDAGADAAITQYFFNIDSY
SSFVEDTEKLGVSIPIVPGIMPITNYAQLARFSDACGAEIPRWIRKRLEAYGDDLESIRA
FGIEVITLMCDKLLSEEVPGLHFYTMNQSHIVLEILENLGLTPIE
>A0A3M1RVG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAEPHLPNVSFEFFPPRTPEMEAVLWASVQRLAPLAPRFVSVTYGADGSTRDRTHRIVAR
VLRETDLVCAPHLTCVGASRDEIDAIARRYWDEGVRHIVALRGDPPQGCDRYEPYPGGYA
YAADLVAGLRRVADFDISVAAYPEVHPEAPSPEFDLDNLKRKLDAGASRAITQFFFDAEL
FLRFRDRCVAAGIDAPIVPGILPITRFKQTLRFAQMCGASVPPWLHERFAGLDDDDDTRR
LIAANTAIELVTTLQRHGVQDFHFYTLNRAELSYAICHSLGLRPRAAA
>A0A2D5T7S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNKLKKNLEDGVFTVTAEITPPRGADFTSLTAAAEILKPAVSAINLTDGAGAKVRLSSLA
AAIHLKNINIEPILQITCRDRNRIAIQADLLGAAAFGINNVLALAGDSIEVGDDKDAKSV
FDLNSKHLLEVMKKMNEEKTTLSGAKLSKATNFFSAAADTPFDPDNKWRPDRLIEKYSSG
ARFIQTQYCYDIEILNRYMQRLVDYGLTEKLYFIIGLGPLRSAKGASWMRDNLFGTIMPD
SIIKRMNSSKSPRNEGIQICAELMQQVSEIDGVSGAHLMAPGLYEETVSAVKLAGFIK
>A0A1G7QLC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium KHT7|TrEMBL
MTVTEILRNTDKTLFSFEVLPPLRGKSIEQIYKTIDRLIDFNPAFIEITTHRNDYVYKEV
KKDIYKRVEERLRPGTVAIAYAIKQKYNIPVVPHIICSGYSQQETENELFDLSFLDILDL
LVLRGDKSKQDSRFIPKEGGLQYASELCQQINDFNNGKLVYGGQHELPHQFSYGVAGYPE
KHEEAMNMTVDIQALKKKVELGAGYIVTQMFFDNQKYFDFVNRCREVGINVPIVPGLKPL
STINHLTMLPRTFHIDFPEKLSQKLAKCQNNDDVKEVGIEWCIEQCRELREQDVPSLHFY
TMNAAAQIETIMNNL
>A0A8H0XEK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E4694|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6G2VQ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID161|TrEMBL
MALGTASTRTDRARTVRDILATGRRTYSFEFSAPKTAKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCDTPVIPEILPVTSVKMLERLPKLSNAVF
PDALKERILTAKDDPATVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHHPPRA
>A0A7W2I1R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium aroidearum|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWQSGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTAMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A1F6CCR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Handelsmanbacteria sp. (strain RIFCSPLOWO2_12_FULL_64_10)|TrEMBL
MICQLAFADRLRTMGGAGAVEALVELERLGADVIGGNCGSGPAGLLRVIERAGAATEGLL
SAFPNASFPEYVDGRYMYVAEPAYLVESAERLVGAGANLIGGCCGTTPGHIRLIVERLGR
RRPARRVLVPYVPPRRKRRVERAASPPAADFLGRVGKGPLTVVELKPPRGTGYEPILRWA
RRIAEAGTDAFSLVENSLAVVRMSPFALGHIVQEETGTPVIIHCTCRDRNLMGQQSELLG
AHALGIRAILALTGDPASMGDEMGSSSVYDTNSLGLIELVAAMNRGVNRAGNPTQGATSF
VIGGAFNPNASRLEPQVRRLEKKVAKGAQFAMTQPVFDGAILREMYAKTAHIEAPIFAGV
MPLVSGRNAEFLHNEVPGIRIPDGVRRRMAEAGDRGAEEGLAVAAELIDGARDFAPGFYI
MPQLGKYEMALELVRHVKAVAKR
>C6JIG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium varium ATCC 27725|TrEMBL
MKISELFKRKKTIVSFEVFPPNSIYSLEDVYSSIDELAKLQPDFISVTYGAGGATRGNTV
EIASKIKNNNKIEALAHLTCLGAKKNEIDDILKQLRANNIENILALRGDKPKDSTPIGEG
DFKYAQDLISYVKEKREFSIGGAYYPEGHLETNDLLDLFNLKRKVDSGTDFLISQIFFDN
ESFYRFRDKLNKLQINIPLVAGIMPVTNAKQIRKITSMCGCSIPEKFQKILNKYENNTQA
LKEAGTAYATEQIIDLITSDIDGIHLYTMNKVDTAKKIMANIAHIREISGGNR
>B8FJ30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatibacillum aliphaticivorans|TrEMBL
MQLRDKSEAGQFIVLAEMEPPKGVDVTDFTANAIRVKDQVDAFVVPEMNSAVMRMSSLGA
SLILQSKGLPTVMQVNCRDRNRLGLQADLLAAGAIGVRNVMAVTGEDPSFGDHHQASAVY
DIDLIELLKAVRGMTEGKDMAGVDLAGAPSFYCGSTVNAGVRGKALQLEIDEMKRKMDAG
ARFFITPPVFNMNDLSDFMEKASRAEVKVLPTVLLLKSVGMARYIDRHSDHVSVGDALIK
RIMSASDKARECAQIAADTIQAAKNAGLDGVMIATLGWEHMLPQVLNLKPTEAQDAEHDD
PNTSWGKHAGGK
>A0A3A9C9N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium C-53|TrEMBL
MIKDIYAKKRPLFSFEVFPPKKDGEFEAVYSVLDRLAALNPDFISVTYGAGGSNSKKNRE
IAAYIQGNCHIEALAHLTSVGLNKEQLRETVDSLKASGVHNILALRGDRPKTMTDEQFHN
RSFTYAAEMTAFLKEDPALCVAGACYPEKHFEAPDMQTDLTHLKEKADAGADFLITQLFF
DNDSFYRLRENAGKLGIHVPISAGIMPVTSVNQLGTTVSLSGSSVPKQLSDVLAKYADSP
ADMKKAGIDFAISQIEGLLSNGVDGIHIYTMNKPEISEIILKAVK
>A0A0L8MXL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseoflavus|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLAELRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVQHPEGVLYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATQLCARLMAEGSPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A2N9Y138|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snodgrassella alvi|TrEMBL
MSFTPLSFEFFPPRTEEGRRKLAITRKQLSQYQPEYFSCTYGAGGTTRAGTLQTITDILN
DGVAAAPHLACIGASRAEMTGLLQTYKNMGIRHIVALRGDVPSGVGFGHQGLRYANELVG
LIREEFGDWFHIEIAAYPEFHPQSRSAEDDINHFVRKCQAGADSAITQYFFNADSYFWFV
DEVQSRGVNIPIIPGIMPIASFSKLARFSETCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCDHLLQQGAPSLHFYTLNQAGLVSTICQRLGY
>A0A5Q8CQ09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1A.F.Ca.IN.022.07.1.1|TrEMBL
MEKAAIRPSSIDASIEMAPSQVIDSPDLPGLFPSGVRVYITDIGLADTPTLVKAARRVAD
LGYTAVPHMAARRLTTRQALETRVKALAEEAGVRDLLIIGGDVATPAGSFSSSFEVLETG
FVDKYGITEVGVAGHPEGSRDFGDEAAIAALRMKSAWAERTGAKMRVVTQFGFDADKFIA
WADGLAVSGVDLPIHLGVAGPAKITTLLKYAALCGVGNSLNFLKKRSASLAALATSHSPE
SFVGPIEHHLRAKPESAIAQLHVFPFGGIKNTAKWLYERGSWQCLEADDRSSIA
>B8FJ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatibacillum aliphaticivorans|TrEMBL
MSLNTESKLEKILKAGHLAVTSECGPPRGTSLDKIEEKANLIKDCVDAINVTDNQTSVTR
MCSLAACIKIKLMGLEPVLQMVTRDRNRIAMQSDILGAAGFGVNNMLCLSGDHQSFGDCA
TGQNVHDLDSMQLVQTVRHMRDEGKFLGGGDIAGPPKIFVGAAANPFADPFEVRVPRLAK
KIAAGAEFIQTQCIYNVEKFEKWLGIARDRGLTEKVFILAGVTPMKSAGMARYMKNRVPG
MDVPDEIVKRLSDTPKEKQADEGIKICIETMQRLKEVKGVAGFHVMAIEWEEKVPELVEG
AGLYPRPEVD
>A0A4S2J4X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S816|TrEMBL
MTTFSFEFFPPKTPAGERTLWQTIRRVESLRPDFVSVTYGAGGSSRDRTIEVTRRIAAET
TLRSVAHLTAVGHSVAELRHIIGSYAAAGIRDVLALRGDPPGDPRGPWVPHPDGFTHAVQ
LVELVRSLGDFRIGVAAFPERHPRSPDWDSEIRHFVAKCKAGADYAITQMFFHADDYLRL
RDRAAAAGCDIPIIPEIMPATDVRQIRRFAELSGAAFPEDLAHRLEAARDDPAAAHRIGV
DHATAMADRLLTEGAPGLHYITLNRSTAALDIHRALHVSRSTSVR
>A0A2Z4IQ10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Echinicola strongylocentroti|TrEMBL
MKVTEHIKQAKSTLFSFEILPPLKGQSLNDMLDGISPLMDFNPPFIDVTYHREEYIYKKH
SNGLLEKVSTRKRPGTVGICAALMNRFNVDTVPHILCGGFNKEETENVLIDLNFIGVENV
LALRGDAPKSEGRFVPEEGGHHYSNELVEQIVGMNHGRYLHEETETGFQTDFCVGVAGYP
EKHFEAPSFKFDLKYLKAKVDAGAEYIVTQMFFDNQKYFEFVKQVREAGITIPIIPGLKP
ITTLRQITVLPSIFFLDLPDQLMDELEKCKDNAAVRQVGIEWAIQQSKELVEFGVPCLHY
YTMSKASTVHKVASAVF
>A0A2Z5SDN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sulfurreducens|TrEMBL
MTGTPSSLSAGLAAGRFIVTTEICPPKGSDCTEFLRKARALRPAIDAVNVTDNQGANMRI
SPLAPAALLVREGIEPILQLTCRDRNRMALQSELLAASALGITNVLALTGDFITFGDHRE
AKPVFDLDSVQLLRIITGLNEGRDLSGTALTGATSFFAGAAAAPEAEPFALTLSKLAKKA
TAGARFLQTQAVFSPERFARFADATRPLGMKIIAGILLLKSPGMARYVTERVPGLKVPPE
LVAELESAGDPLAAGVEIARRTVAAVRPFCDGVHIMAMGREDLVPAIVAGVERDSQEHTT
I
>A0A433RWX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kurthia sp. 3B1D|TrEMBL
MGLLNDLKTKVLTADGAMGTLLYSYGIDYCYEELNVSKPEIIEDIHKRYIESGADIIQTN
TYTANAIKLARYGIEDQVVAINEGAVAIAKRAAAPGGQYVLGTIGGIRGIRKTDETLEEI
LEALHTQATILIEGGVDGLLLETFYDFEELSALVKLLRAHTALPIIAQVSMHEPGVLQNG
VSLNEALHTLESLGANIVGVNCRLGPHHTIQAFENVELPETAFLSAYPNASLLDVEDGKV
VYESEADYFGRAAVLLRDEGVRLIGGCCGTTPAHIAEVKKRLADLPPIKAKIVEKKKSLI
IKDADEAAHEPLHVQAKKQRTIIVELDTPRHLETDAFVDGARILQDAGADAVTMADNSLA
SPRVSNMAMGARLKYEKNVRALAHITCRDRNLIGLQSHLMGLDALGITDILAVTGDPTKV
GDFPGATSVYDVSSIELLELIKKLNEGISFSGKPLRKKANFSVAGAFNPNVRNVARAVPR
LEKKIAAGADYFISQPVYTKEKIIEVYEATKHIEEPIFLGIMPLTSLRNSEFLHNEVPGI
KLSEDVLTRMRDCEEDKERARAEGLKIAKELIDVAAPLFKGIYLITPFMRYDMTVELIDY
IKQLDAQTEGEQVNVETTH
>A0A2J8KXB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pan troglodytes|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKANHSG
>A0A1R3JPJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corchorus capsularis|TrEMBL
MKVIDKIKSLQGGEGDNGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAG
GSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPH
GQDKFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDAIGSNGVATPEAYQNDL
EYLKRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGF
CKTKIPAEVTAALEPIKDNEEAVKSYGIHLGTEMCRKILAHGIKTVHLYTLNMEKSALAI
LMNLGLIEESKISRNLPWRRPANIFRVKEDVRPIFWANRPKSYITRTLGWDQYPHGRWGD
SRNPSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNYCLGKLRSSPWSELDG
LQPETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCPE
EKLDALVDKCKAFSFITYIAVNKTGNLLSNIGVADVNAVTWGVFPAKEVIQPTVVDPASF
MVWKDEAFEIWSRTWAALYPDGDPSKKLLEEVQSNCYLVSLVDNDYVGGDIFAAFEDL
>A0A3D3IFR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagales bacterium|TrEMBL
MKVTEHLKNANGKTLFSIEILPPLKGENIRRLFDHMDPLMEFKPPFVDVTYHREEYVYKK
KENGLLEKQSTRKRPGTVGICAAIQNHYKVDTVPHIICGGFSKEETENALIDLQFLGIDN
VLVLQGDAIKNEGRFVPEPDGHHYASELLEQVIKMNHGIYLDEELQNMTPTNFCVGVAGY
PEKHFWAPNLKTDMKYLKAKVDMGAEYIVTQMFFDNKKYFDFVENCRAIGIEVPIIPGLK
PITTKAQSNILPTIFHIDLPEELADEVEKCKDNNAVKEVGVEWAINQSRELMKQGVPTLH
YYSMGKSDPIYRIAKELF
>A0A2G6RMT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. 13|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVNRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A2G9SV33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium sp. 445|TrEMBL
MLVKDILRSNKAAFSFEFFPPKQEADWDKLFHTIADLMTLKPSYVSVTYGAGGTTRERTH
NLVVRIQQETSLTVVSHLTTVGSSKEEIYQILKRYDENGVHNILALRGDPPKNMPNWTPE
HQDFKFAAELVSFIKMHFPHMGIGVAGFPEGHPATPNRLKEMDYLKMKVDAGADYIVTQL
FFDNHYFYDFCERCELAGIRVPIIAGIMPITTRSGMNRMAELSPGTCFPAKLLRAINRVK
DEADVEKVGVHWATEQVADLMHNGVKGIHFYTLNSSRATLKIYETLGVQDSEQLAAV
>A0A521G7P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagales bacterium|TrEMBL
MTKITDHIRNANGKPIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYMER
PMPDGTIKKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFSRDETEDFLIDLHYLGID
NVLVLRGDPAKPFNTFKAKENGYSYASELVEQVANMNRGQYLHEEDAELAPSNFCVGVAA
YPEKHFEAIDHDTDFDFLKQKIDKGADYIVTQMFFDNSKFFDFVKRCREHGITIPIIPGL
KPLSTRKQLEILPRIFHLHMPDDLVKAVQACENDTQARQVGIEWGIQQSRELMAAGAPVL
HYYTMGKADNVAKIAQEVF
>A0A417DCA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM42-10AC|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>K9UWZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix sp. PCC 6303|TrEMBL
MVMLNTRNFTALSSFRTAAKAGEFLVTAEVAPPKGGNTEHMLAMTATLKGRVHAINITDG
SRAVLRMSSLVASLILQENGIEPICQMACRDRNRIGLQADLMGAHAVGIRNILALTGDPV
KAGDHPTCKGVFDLESVRLLQVIQKLNIGLDANDKPLTDGSLDLFPGAAIDPQCPSFSGL
QSRFEKKLAAGAQFFQSQLITDFEKLEKFMDAIACGTNKPILAGIFLLKSAKNAEFINRV
VPGVTIPQHIIERLRAAKDPLEEGMKIAAEQVQIAKQLCQGVHMMSVKREDLIAPILDMA
GVKPVNLVTK
>A0A1H8C3E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. OV219|TrEMBL
MEQMLRDKLLAKKPGIISYGMTPPKATNTTEKIAEIAQKQCERLRDLELDALILYDVQEE
ADRIEQERPFPYLQTVSPDTYSKQYLSGLDVPKIIYKCVGNYSEAEFTDWATSDADQDKY
SVFVGSSSNRQHVHLGLKDAYQLSKQHNRNLTFGGVIIPERHMTKQDEHLRVVSKMKNGC
DFFVTQAIYNVEASKNFLSDYYYYCNENGIDMVPILFNLAPCGSTKTLEFMKWLGISIPK
WLENDLKYSSDVLDQSIRHCQKIFEEIFEYGLEKGIPIGCSIESVSTRKVEIDASVQLVK
NIKSVLNKKLNHTAVK
>A0A2G8MUN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 382|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKDELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEADLGNFVHKVKAGADSAITQYFFNADSYFY
FVERAQKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLAIWNNLKLPR
>A0A374J7N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. OM08-9BH|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVQLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAEI
>A0A1A9CY21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. OspMP-M45|TrEMBL
MHPLDTASASVGTPLLEDFSLEMTGKDVPELEAADGTLPRGTRVNVTFLGNEDPRMRLDA
ARAVKRLGLLPVPHISARRLTSRTDFEQFLAGLRDDGTATHVFTVGGDPALPQGPYDSAL
ALIDSGLLQEHGVRHVGIAGYPEGHPALTDDTLRAALRDKAASLTAHGLTGHVTTQFGFD
PDPVLSWLEDVRDQGITLPVRIGVPGPAGVRRLLSYATRFGVGTSASIARKYGLSLTNLM
GTTGPDAFLRTLAERYDPARHGEVKIHFYTFGGLRATAEWIARFRQDNLV
>A0A0B7N7D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasitella parasitica|TrEMBL
MARVKFFQNQGILSLLLIAMVLFSMVPKVKAWTEADFEIFDIVDALEKAEGKDVNFYNWI
GVAPSATQNEISKAYRKLSLKWHPDKNKGDPKAKERFTRLGVIVSILRDPRSRERYNFFY
KNGVPRWRGTGYLYSRFRPGLGTVTVVLLLIAAGMQHIAGQINYHQEKRKISQFVAEARS
HMIHDAPKGRAATLGRSYIEVGQRNMRCEVKGDNYIVVYPDERTGEPIHLNTEWVTKPAV
NNLFIIAWPKRLIYKVLGKKEEFEDEYEEEIAEGDQAVEEEQKANADSSSTKKKSLRKRG
GGEKGFANLIDRLGRMAKLEPEFISCTWGAGGSTHDRTLELCTIAQSLYGLDTLMHLTCT
NMEKAKIDEALEQAKKAGIRNILALRGDPPRGHEYWTPVDNQFQHAIDLVKYIRQHYGDT
FCIGVAGYPEGHIDCPDKEQDMQYLREKVDAGADFILTQLFYDVEACVTWMQKCRAHGIQ
VPIVPGIMPIPTYQSFRRMINLCNVKVPANVMSDLDAIKGDDQKVKEYGVNLAVEMIQAL
HKEAGICNFHISTLNLERSTRLILEALHLHKETGLQAKKVSPWAPIHDPAKAELWDEFPN
GRYGDSRSPAYGENTYSAGQILPTSQAISKWGQPETEQDITELFVDYINGQVKSLPWCEE
ALHTESEAIRQRLTDINQRGYWTVSSQPAVNGASSQDEVYGWGPKNGYVYQKAFIEFFVS
DQQVGELLCRLAKDDSITYYATNQKGDFSTNVSDADAQNAVTWGVFPGKEIIQPTIIEKA
SFEAWKEEAFSLWTEWEEQYAPGSTSKKILHDIRDRYWLVNVVHNDFQKSNLLFDVMLS
>A0A538TPZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium|TrEMBL
MTHPFLTRLERGPVLADGAMGTYLYERGIPFDRSFDLLNLTDAPLVQAVHRDYIRAGAEL
VETNTFGANRFRLAAHGATESARVVNRAGAQLARNAREEVGEAVFVAGAIGPLGKPVAPL
GTITREEALEAYREQVEGLVEGGVDLLIIETQTDLAEAAIAIEAARSVTDHHPLVLQMTF
TEDGRTLYGAYPEDVARDVDGKQVDVLGANCSVGPQKLLEIVERLRRRTKLPISVMPNAG
LPRFVDGRFVYVSSPEYMAEYATRFAAAGARLIGGCCGTTPIHTRKMREALRASAKSGVA
PAPVDGPPAPSVTVTTYEDTAPAADPADRTRLSRKLADKEFVVSVEVDPPRGARPKKMIE
GAQFLKRAGVDVINVADSPMARVRMSSIALASMITNHVGIETILHFTCRDRNLMGIQSDL
MGSHALGIRNILALTGDPPRAGDYPNATAVFDVDSVGLIRVLKQLNAGTDLGGNSIGEPT
AFLIGCAVNPTAENFDQEMERFEKKIEAGAEFAMTQPLYELDTLVRFLNRLGKARIPVLL
GLLPLQSHRHAEFLHNEVPGINIPDYARAAMRDAGEKGIEVGVEMCRKLLLEARDLVEGA
YLMPSFGRYEVVARVAEAVLSGARQSS
>A0A837JHS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter butzleri L354|TrEMBL
MFKTLIQKLQEDKYLTLETTPQHEPSMHNIIEKIKKFNLQDKIDGFSCTDNPLAKLRYNS
LFAALKLQQEFEKPVIATMTMRDRNKIALQSDLLGANDFDVRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGHPFKIEPKQIFPFAVVNSYAKNFSSLEKKMHLKI
QNGAIGIITQPIFDIENAQKLLESFDIAKENVEGDKRKSQLIFGIFPVTKLRTALFLSAQ
VPGIHVPQFWIDALEKAHSIGEEEEYKVGMELSSNLFKELNKLHPKIHLMTANRFDVANE
IIS
>A0A3N6EH40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus xylanexedens|TrEMBL
MKADLRKVMQERVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQISALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFAELGARIIGGCCGTTPDHITAMKEALADYIPSPILEPDPSE
SKPRIVLHEHVDERSGRGGQSTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLEKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFIGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>H5XCL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora cyanea NA-134|TrEMBL
MRRRDHARRPFEVPAALAPWLPEARFEVLPLPGVLDQTARLAEGTTVTVTASPSRGLDAT
VELCEKLAAQRLHAVAHLAARQLHDAVHLRDVLDRLAGSGLDEVFVIAGDARTPVGPFGD
GLSLLRAIEESGRRPRRVGVPCYPEGHPTIPEDALWTALTAKQSHADYAVSQLCFDATVV
CRFLRAARERGVTLPVRIGLAGVVDPGTLLRIGSRIGVGDSLSFLRKNRSVLAGLARPNR
HDPGRFLTALAGELAGGDCAPAGLHFYTFNRVTATAEWLDAVRPPRAE
>A0A1V2ART8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MIRKRTKFKLHDISTSPAIAASIEASPAQVLGPASLAGIFPQGVRVYLTDTGQASQDRLV
DAAKHLRDLGYTPVPHLAARRISSRVEFEEQVKRLAGEAGVSDVLVVGGGVATPAGPFAS
SMDMLSTGIFDRCGINQIAIAGHPEGSPDFSDETATAALKLKCDFAERSDAAMRIVTQFG
FDPTRFIAWAEGLAASGIDLPVHIGVSGPARITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESVVGPIERHWQANPAGPIRQIHVFPFGGLQNSADWLAGRGSWQTGDADFSTK
RGTVAI
>A0A1Z8UVT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacteraceae bacterium TMED65|TrEMBL
MTYSQINVSFEFFPPKNEDSIASLWNNIKRLEPLKPRFISVTYGAGGSTRENTHSLVKEI
KEKTSLNPAAHLTCIGTSKSEIERIADEYWSSGIKHIVALRGDERENGHGSVKDFKYATD
LIKVLKDRFDFEITVSAYPEMHPDSKSMDQEYDVLKKKIDLGASKAITQFFFDIDCYFEF
VDGALKRGIKIPIIPGILPVTNCKRTFEFAKKMNCKMPKSLIEMFDGLDSDPETRKLVAT
TVVHDQCKKLLEGKVNDFHFYTLNRADLSFAICHILGIRS
>A0A1E3I4J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus amylolentus CBS 6039|TrEMBL
MPPLTSLIAAHDGPFHNYEFFPPRTDAGLVNLLERIRRLTSAPLQRPLAVSITWGAGGST
AEKSLELAEQVVKMGVEVVLHLTCTNMAKEKVDLALQKCKALGIQNILALRGDPPRSEEY
AVTPNVPDFFQHADDLVRYIRAEHGAYFCIGVAGYPTAHPDSETDEDEMKWLKVKCDAGA
DFIVTQLFYDVDGFLAWVKECRAQGIKQTIIPGIMPIQSFGSFRRLVNLTKCPVPSSITS
DLQPISSDDAAVKQYGATLATKMVKQILDSGEIHGVHFCTLNLEKSVRTILDNLNWVERD
QRDSVSSLDRNRFIESDEDARPSGIPINGKTRSYSNSASLSISPSDASHLAQLGLTSALP
PKSQAHSTATGAPSGAGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKE
WGVPTTSSDLSTLFTSYLQNSPATPTTPFCDLPLSPESQTILPHLLKLNSADKCFWTVGS
QPAVDAAKSEDSVVGWGPRGGYVFQKAFVEFFVRPEEVEGLVRKVDELGKSMITLYASNK
KGDFKTNTDSSAVNAVTWGVFPGQEIVQSTIIEQESFLAWKEEAFDIWTEWAELYPRQSA
ARKLLEGVSGEWWLVSLIHHDYKKEDALWKFLLDV
>A0A2U0SRV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. 78|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRIKLSELQPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRASIRAVLADFKAAGVSRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLQAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A0X3Y8L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rheinheimera sp. EpRS3|TrEMBL
MAFANAQYLDAINRNLQDVEGKVNVSFEFFPPKTPQMEQTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDATKDDLIAIAKDYWQNGIRHIVALRGD
LPPGNTSKPDLYAADLVEILRSVADFDISVAAYPEMHPEAPNTQFDLLNLKRKVDAGASR
AITQFFFDAEKFLRYRDRCAAIGIDVDIVPGILPVTNFQQLKKFAALTNVAVPNWMHKAY
EGLENDATTRNLVAANIAMEMVKVLSREGVDHFHFYTLNRSELSYAICHLLGVRPQAAV
>A0A4P7SNS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. PAMC25564|TrEMBL
MMFPTRIEIIPSEGIVEQVQAVVPLTTTLTVTCLPHHGIERTMRAAVQLSMLGYRVIPHL
AARSLHSRAELTGIMRDCNVAGIGEVFVIGGDRKQPAGPYQSALPLLEDIAQHSGGAMRA
GIAGYPEGHPAVGPLDLLDALLAKQHLATHVVTQMCFSAPTVLDYAALLRREGVQLPVWA
GVAGSVPRTKLVSLATQIGVGSSLKFLSRKGPLARKLLSGDRYSPHNLVAGLEIQPGSIA
GIHLYSFNNLDSVSDEPFPASTPAALQPALIRGAASVI
>W8I2S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer adhaerens OV14|TrEMBL
MSPDYNPYDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNVMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHETLPTDALVASRMEHIREGKEENQQEMAEAAAH
HPH
>C1CUZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus deserti (strain DSM 17065 / CIP 109153 / LMG 22923 / VCD115)|TrEMBL
MTRVSIELVPRSRSALRAELQAVAEHLPGVDTVNIPDLTRFSTRSWHGCAFARPHYRAIP
HIRAVDLNPHEPLPMAAHLDEHGLDEVLIVSGDAPADMSARVYDVDAITAIRRFARELPH
VRVYAGLDPYRQSLAREQDYLERKLEAGAVGFFTQPFFDLRLMETYADLIPQQAEVWWGA
TSVTEEGSLNYWRTRNHAVFPRSFQPTLEWNRQFAAQMLAFAQERNQHAYFMPVRADTLA
YLGGLL
>A0A5Q0DHR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes faecalis|TrEMBL
MSNQQTLSLEFFPPRDIAAQEKLVRTAKSLMGLNPAYVSMTFGAGGSTRAGTVDAVALLQ
KLGFDVAPHLSCIGTAPAQLSEMLDNYRDQGIRRIVALRGDLPSGMGGDAGELRYASDLV
AFIRENYGEQFHIEVAAYPEMHPQATGFGDDLDHFVNKVNAGAHGAITQYFFNPDSYFSF
VERAQAQGVTIPITPGIMPITNSSQLLRFSTMCGAEVPRWIRLRLADFGDDRASIRAFGI
DVVARLCQDLLDGGAPGIHMYTLNGADASMAILPNLTWR
>A0A7W8ISF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus tepidamans|TrEMBL
MGLLEDLKERIVIADGAMGTLLYSHGVDRCFEELNLSKPDEIVHIHEAYIAAGAEVIQTN
TYGANYVKLARYGLQDDVQAINRAAVQLAKQAAMGRAYVLGTIGGLRSINKSAITLEEVK
RTFREQLYVLLHEDVDGLLLETYYDLEELKTVLAIARKETDKPIIAHVTLHDAGVLQDGT
PLADALTQLEQLGADVVGLNCHLGPYHMIRSLEEVPLPTNAFLSAYPNASLPDYRDGRLV
YETNADYFKETALAFRDQGVRLIGGCCGTTPKHIEAMAKALTDRTPIEQKCVKQRAVNIS
VQSPDQKTEPPLQDIVCQRRSVIVELDPPKKLGITKFLEGAKALKEANIDALTLADNSLA
TPRISNVALGTIVKQQIGVRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLAVTGDPSKI
GDFPGATSVYDLSSFDLIQLIRQFNEGLSYSGQPLGQKTNFSIAAAFNPNVRYLDKAVQR
LEKKIQCGAHYFISQPLYSERQIEEVYEATKHLKTPIYIGIMPLTSARNADFLHHEVPGI
TLSDDIRARMAACANDPIQSAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYEMTVELVHY
IHEKERSAKERKVLHG
>A0A7C2H961|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenobaculum sp|TrEMBL
MKIIELLKNKKGISFEFFPPKSQKDKETLLETARELKVFEPNFVSVTHGASGNSTSQK
>A0A7Y5RHF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriaceae bacterium|TrEMBL
MVETSESLLETLIAPGRTVLCDGAMGTMLYARGVFINRCYDELNLSQPDLIRSIHEEYLH
AGAEMIETNTFGANAIRLARYGLADKVSAINHAGVALARKAAQHSEEKTGAHAYVAGAIG
PLGARLAPAGTITVQQAHDAFAEQIAALAAAGADLLIAETFPSVAEAEIVVRAARDIAPH
LPLFVMVTVDDNGNTLDGTTAEETATRLTIAGANAVGCNCSSGPHAVLDVIERMRAVTHL
PLAAMPNAGLPRAVDGRNIYLTSPEYMASFARKFAKAGATFIGGCCGTTPNHIKAMRSAL
RAIDAQVTAKAEVTDETQAAVQPPPFGERSKLAGLLANRQFVSMVEIVPPLGVNCQKELD
GAKKLADLGVHVINVPDSPRASARMSAQSLCVQIQHTIGIETLIHVTCRDRNLLAIQSDM
LGASSIGLKNVLCLTGDPPKLGNYPDATAVFDVDAIGLVNILRNLNHGLDLGKNPIGQSA
AFAIGVAANPGVPDVDNEVRRFALKVEAGAEYAITQPVFDMRLLETFLRRVEEFRIPVIA
GIWPLTSLRNAEFMKNDLRVAVPDEIMFRMHKAGEVSADHARAEGIKIAQEMLAHTRPQV
EGVQVSAPFGKYTAAAQVLELLG
>A0A7X6DUE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Manganitrophus noduliformans|TrEMBL
MKIPAYFESGRPIFSFEFFPPKTEEGVEHLFRTIGELKALAPAFVSVTYGAGGSNRQRTV
EVVKRIKGEHGVEAMAHLTCVGSDRDEIDRVLGQLKEAGIENVLALRGDPPKGEATFTRT
ADGFSYAYELVAYIRKRHHFSIGGACYPEGHVECRDLDKDLGHLKTKVDTGLDFIITQLF
FDNRCYFDFVKRARAIGIGVPILPGIMPITNVGQVKRFTEMCGASIPASLLCELEAVQDD
PAAVMALGIGHAATQCRELLSNGAPGIHFYTLNKSPATRAILRSLSDLR
>A0A5E5PW35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Gammaproteobacteria bacterium|TrEMBL
RQELSSLNPEYFSVTFGALGTTQEATLETVLDIQKNDTVAAAPHLSCIGSKKEIIITLLD
QYKAANINRLVALRGDIPSGVRDIGDFHYANELVEFVKSQYNNHFHIEVAAYPEVHPESK
NRLTDLQHFADKVSAGADGAITQYFYDADAYFKFVDATEKLGINIPIVPGIMPITNYTQL
VRFSNMCGAKIPSWILKKLELYQDDLDSLSAFGLEVVTNLCQTLKAQGVDNFHFYSMNHS
QPSLEIAKHL
>A0A5E5PTT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Gammaproteobacteria bacterium|TrEMBL
MNPISSFNTNLIRTSLLSIVLTHTAIAGGPIDGRSLMDDYLQNKASASTDPATPSTAINI
SNISLNSANYYNEFQSDVNTNDNTANGNKKSLSTIISNKLSALNLSNYNAKMIRNHAEVM
SCGGCHQNSNEVEIAQNVNWPKSGTFVHVDKQGVLSSALTEQFLPAQSALLKVYWQTIVE
KWHFSEMDYSSARNYFGGFNNVPSYPNASAFATLQADGSIKAWGNSESGGTNAPTDKGYT
KIYSTIDAFAALKADGSIKAWGNSDSGGSGAPDGSGYTKIYSTDRAFAALKTDGSITAWG
APGLGGLDAPAGTDYTKIYSTASAFAALKADGSITAWGDSDSGGIDAPAGTDYTKIYSTA
SAFAALKADGSITAWGDSDSGGIDAPAGTDYTKIYSTASAFAALKADGSITAWGNPGSGG
IDAPAGSGYTKIYSNGAAFAALKADGSIT
>A0A161X5A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Daucus carota subsp. sativus|TrEMBL
MESFSSEPLATESFSYSWLVQQTPQFHGLEEYLTSTSSPRDTNFNFDTSISRSSSFNFVH
ADEIFSNGHIIPFYLDRTKSNVEAFNTLSSLPDPIPISSSDRMKFYYFFKNLRTSSKRLI
RGWLRMLRPLCHKVGCSRKSIRVDDIDRKKWEIRSLENLNISIEAAPSMSKKSEYRRLKK
ARSWSSKAQESVPTSPCWFDNESSIYEAVLHCKRSIGCWGSGEHSRLEGIILGQLWYLAE
SFWVVISSGTALVDCGADVIVTQLFYDTDISLKSVNDCRQIGITIPIVTSNAGIMPINNY
KGFLRMTGFCKTKNKAYSGVFDKYECDCAAAKLRGRGPGVNNMGNSQQPVLAHHKDPLVA
PRRRGRRPGVEKRLAQRFGEESGNTIKNQTSAEDAKKCGNNDKSRVKGMSVANSGSIGDR
KFFTLICSFFLTTCMPWQFSQYLAIAAAACQILIWIKRQPLRTLDINARVLERPVSVHKF
IDEEIENHPSVTENSASGGAGSDSMLVDQAKQKKDIQVNVTMWSVDNILGDKVKEYEFSG
SKLHPEELTIMEQRIEEREKCEASAEQIDLCRKGVHVRA
>S2J0V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor circinelloides f. circinelloides (strain 1006PhL)|TrEMBL
MKIIDKIEQAQKSNHIAYSFEYFPPKTELGFANLIDRLGRMAQLEPEFVSCTWGAGGSTH
DRTLELCTTAQSLYGLDTLMHLTCTNMEKVKIDEALEQAKEAGIRNILALRGDPPRGHEY
WTPVDSEFQHAIDLVKYIRKHYGDTFCIGVAGYPEGHIDCPDKEQDMQYLKEKVDAGADF
VMTQLFYDVDACVTWMQKCRAHGIQVPIVPGIMPIPTYQSFRRMINLCNVKVPDNVMSDL
DAIKGDDQKVKEYGVNLAVNMIQRLHKEAGICNFHISTLNLERSTRLILEALHLHKENGL
QVNKVSPWAPIHDPAKAELWDEFPNGRYGDSRSPAYGENTYSSGQILPTSQAILKWGEPE
TEQDIAQLFINYINGQVKSLPWCEEALHTESETIRQRLTDINQRGYWTVSSQPAVNGASS
QDKIYGWGPKNGYVYQKAFIEFFVSDQQVAALLSRLGKDESITYYATNRKGDFSTNVSDA
EAQNAVTWGVFPGKEIIQPTIIEKASFEAWKDEAFSLWTEWEEQYAPNSSSQKILKEIGD
RYWLVNVVHNDFQKPDLLFDVMLS
>A0A5R9A9V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas nitroreducens|TrEMBL
MSQKERRFSFEFFPAKTEAGHEKLLATASQLAAKKPDFFSCTYGAGGSTRDRTLTTVLQL
DGEVKVPTAPHLSCVGDTKPELRALLAHYKDAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRAETGDHFHIEVAAYPEVHPQARNFEDDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAEKLGVSIPVVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDIASIQAF
GEQVITEMCERLLEGGAPGLHFYTLNQAEPSLALWNNLKLPR
>A0A4D6YNH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MITKQKIKKIYYNGFSNLSEKIYFSFEFFPPKNIENDIQLEVIAKKLSEYEPSFFSITYS
PIHKNRYRTQNMALKIQKITNIPTAAHLTCTEISQEDLITIIKNYWKNGIHNIVALRGDI
INKNFNQNQMYAIDLVKLLKNIANFDITVAAYPEMHPEAISKKQDLLFLKQKIEAGANRA
ITQFFFDVDKYLYFREQCIKIGITKNIIPGILPIKNLLQLKKFSKLTNVHIPKDIHEIFN
TKNNNNNEYNNIIGSIFTFCIIKKLYQEGVRHFHFYTLNDFITITAMCNLLKNINAIN
>A0A0D2GMI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dethiosulfatarculus sandiegensis|TrEMBL
MALADILRSKDFLVLAEMETPKGVNLSDFVENARHIKGRVDAVLIPDMAYAIMRLSAMAG
AVVLKEQGLEAIVQFSCRDRNRLALQGDLLGAQVLGLGAVMAVEGRPIEMGDHLKAKPVH
DLDVPGFMEAVAALNQGQDLGGKELNGTPRILAGVRLEPWVDKAQAKVRLAEAKQAVDKG
AAFVITPPVFDPGDFASFMEEAKELGVPVFASVMLLKSVGMARYMNQNLPGVNISEDVIR
RIRMASDRTGECVKIAGETVAELRKACQGVLLVTTGWENRMPEILSSAGM
>A0A5B0R7T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia graminis f. sp. tritici|TrEMBL
MAKKVVQLIESLKDDQVYFTFEYFPPKTIDGLSNLYARIQRMANLKPSCAHVTWGASGST
SDTSLEIAAMVQDQLAIPACLHLTCTNIQRTHLDQTLAQAKESGIVNILALRGDPPRGTE
HWIPTDHEFQHAIDLVKYIRKEHQDHFCIGVAAYPEGTTEFDQDQELNYLKQKVDAGADF
IVTQLFYDVDIFLNWVKACRNLGINVPIIPGIMPIQSYDGFRRLTALCKTNIPESIHSKL
IPIKGDDQAVRDYGVELSTQMIKRLQVNGFKSFHLCTLNLERSITRLVNQLGWSPGGIKH
CQPLLGPSVKIGTAEIVQGGLSVGWDEFPNGRFGDQRSPAFGLREGYSSSLTSAFSHLTT
DVHALWGTPTSLKDITQIFCAFTQGKLPSTPWSEEPLALETSSITPFLLKLNQNGWWTVG
SQPAIDGADSLDSVVGFGPQGGRVYQKSFVEFFVPHAHLEGLLSAVDDYNKEHSDGVAQL
RYYAGNCNQDQIRSNMAPGETNAVTWGVFRGAEVVTTTLIEAQSFKTWKKQAFEIWNDWA
ESFEPNSANQRLLNQIEDSYWLCSLIDHDFKQPEHLWSFLIAHQQRLLSHQSL
>A0A2E6KQ68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Legionellales bacterium|TrEMBL
MELSFEFFPPRNNKEYKSLEETYKVLSKFEPTFVSFTDGAGASKNRDIIKSVKILRKYSE
TEVVAHITSCDKEKIDVDVLIDEYQKXDITSFLVIRGDCPTNEFLIDPDEIDFSGENEFR
HASDLIEYLKSKGIXNIGFGAFPTGHPEDKSFEQTVEXFKIKSNLGGNFSATQLFFDSXE
YKIFFNKMKESNNEVPIYAGIMPLLSLDQAKRFAQICDVELPSKLEQGFEKCSSKEEERE
YGIKYITKMCNELIDFGADGLHFYTLNRSKAFVDIXNNLEFKKXN
>Q9ACM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus thermophilus|TrEMBL
AGCSSLVTQLFFDNERFYDFQDKCTLAGIDVPIYAGIMPILNRNQALRLLKTCENIHLPR
KFRAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNAETARHIYEATHSL
FKHHSQVGAL
>V5F456|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium leiognathi lrivu.4.1|TrEMBL
MSDQYLSSQESELRVRYNDITRGVYFIGTTPPKTSTPLEDVEGIADRLVDRICDLAIDGL
IVYDIQDEASRTNKPRPFPFKSTHDPRHYSSLLNKKTDKPVITYKSVVQSETEEFDAWLN
EAWDEYRVRDMVLVGSPSAKNEVSLPLSAAYQTLADNRNNFFTGGIMIAERHAKKGNEHE
RLIEKYKQGCNFFISQAIYDTQATIDILTRYAIECKEQGLKPQRIILTFSPCGSAKTLEF
IEWLGVSVPEATSLRILNAENPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRKE
EIDGSILLYKLLRSSMDSHLAKHEFRVLKRKARANKQASV
>A0A4R2NG61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scopulibacillus darangshiensis|TrEMBL
MSLLQALKERILIGDGAMGTLLYSYGIDRCFEELNFSHEEEVLHVHQAYVEAGADIIQTN
TYGANYIKLSRYGLEDEVKKINSQAVRIAKKAKKDGTFVVGTIGGIRGFKRQAVSAEEIK
RSFREQLYCLLLEGVDGLLLETYYDFEELTEVLKIAREETGLPVLTHVSMHEPGILQNGK
SLDSALQELEGLGADVVGVNCRLGPYHMVQALETVPIPSKAFLSAYPNASLPEYRDGKLF
YQTETDYFKKCAAAFRDQGVRLLGGCCGTTPEHIKAFAEGIKFLTPLQEKEITRKAEHIE
ISQPAVKREPPLFEKAKTERSVIVEFDAPKHLDTKKFFEGAKALKASGIDAITLADNSLA
TPRISNAAIASILKQNVDLTPLVHITCRDRNLIGLQSHLMGLHVLGIHEVLAVTGDPTKI
GDFPGASSVYDVSSFDLIQLIKQFNQGLSFSGKTLKQQTVFSVAAAFNPNVHSLDRAVKR
MEKKIAYGADYFITQPIFDHERILALKEATKHLDVPIYIGIMPLTSSKNAEFLHNEVPGM
RLTDDVRNRIAAASIHPETATKEGIAIAKELIDTAMEHFNGIYLITPFTRYDMTVQLTHY
IREKAPKQREGLGISEHTFT
>A0A7D5VAC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinibacter fontanus|TrEMBL
MPTNLHTKITQRQPGIILYGITPPKANNTPEKIAEIAALQVERIAPLNVDGLVLYDIQDE
ADRTDAARPFPFLATLDPLTYSRDYLAALDIPKINYRCVGKYSPEQFRADLSALGNGVSV
FVGAASREQQVSLSVAQAYALRRETNPDLLVGGVAIPERHLVKNDEHIRVAHKVAEGCSF
FVTQCVYNVEAAKNFLSDYYYACQASGTAMVPIIFTITPCGSVKTLEFMKWLGISIPKWL
ENDLIHSGDILAKSLDVCKRIFSELLQYANEKGIPVGCNVESVAIRKDEIEASLQLVRDV
QAMFSRV
>A0A7C7E378|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterales bacterium|TrEMBL
MQIKELFNKGPVISLEIFPPKPESPIDTVMDTIKALSDLKPDFISVTYGAGGSGKAYTFE
IADIIKNKYGIESLAHLTCINSKKEDIDCVLRKLNSADIENILALRGDIPEDK
>A0A1Q8VHU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MRDNEPTEPTATAGSRGDGLSNAETGAVRPLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPAGGISGAGHEESPSEPAAGQREAVPRVRVVQEQTNPSESVLAH
VLECSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRADDVAGELRH
ADDLVRVIREVEADFFGDGRRHVTIAVAAYPATSDHIEAIEVLAAKQAAGADMAITQVFY
DAADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPESLRSSLGSASGAT
LVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDA
VDRGYLQATPGRGPSFLRCGSPGAALSSRHPVQPHTTITKENA
>A0A8G1UIV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora cineracea|TrEMBL
MALGIPSTRSDRAQTVRDLLAAGDRSFSFEFMPPRNEEGERKLWDAIRRVECLEPNFVCM
TYGAGGSSRGRTVDLVGRIATETTLTPVAHLTAVDHSVAELRNIIGQYADQNVRNVLAVR
GDPPGDPMGEWVRHPEGVSYAAELVGLIKDIGDFCVGVAAFPQMHPRSENWDEDIRHFVA
KCRAGADYAITQMFFEVEDYLRLRDRVAAAGCDTPIIPEIMPVTNIRQLVRFPQLSGSDF
PPDFRRKLESVADDPVAVRAAGLEHATAMAERLLAEGAPGLHFITLNHSTSTLEIYQNLG
LHTR
>A0A2E9WA62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira sp|TrEMBL
MTAQNNTAAKNDLRVSFEFFPPKTEKMEETMWRSIHRLAPLSPSFVSVTYGAGGTTRDRT
HSSVTRIQGETGIPAAAHLTCVGHTKQEIEQIARKYWDEGIRSIVALRGDLPDAGDTYVP
TPGGYDYAADLVAGLKEIADFDISVSAYPEMHPDAPSADFEIDYLKRKLDAGANRAITQF
FFDNETYLRFRDKCQAAGITAPIVPGILPVTNFGSLLRFAKMCGADVPKRFHWRFDGLDD
DPDTRRMVAFHEAISQVEGLMKEGVTDFHFYTLNRAELTYAICHALGIRGTEQAVA
>A0A255ZZ22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium aurantiibacter|TrEMBL
MKITEHIQNAKETLFSFEILPPLKGENIDSIFQSIEPLMEFKPPFIDVTYHREEVAYTEL
PGGLLKKRIVKKRPGTVGICAAIQNKYGVDAVPHILCGGFSKEDTENFLIDIDFLGIENV
VALRGDAVKNEIYFRPEPDGHKYASELVTQIVALNNGIYLDEELENKSKTNFCIGVAGYP
EKHMEAPNLDTDIAFLKQKIDAGAHYVVTQMFFDNQKFFAFVEKCRAAGITVPIIPGLKP
LTSLKQLSMIPQRFRVDLPDELISELYKTKSADAAKQAGIEWCISQSLELKKAGVEVLHY
YSMGKSESISKIAKAVF
>A0A414ZAG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AM16-24|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELACEAMKCKTDEEAKQVGIEWCVKQCKELMEHGVPSIHF
YSIGAVDSIKEVAKLVY
>E0DG42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium matruchotii ATCC 14266|TrEMBL
MTQQPLPEPTPARYQRSITDVISSPAPGRIPFSVEFMPPRNDEAETRLRTAAEIFHDLGV
AFVSVTYGAGGSSRDRTMRIAQDLARMPLTTLVHLTLVGHTEAELVEILSDYASLGLSNL
LALRGDPPGADPLGEWTPVPGGYRYAEELIWLTKRLEATKHFQVGIAAFPEGHHQSESLA
ADTKYTLAKLRAGAEFSITQMFFDVDYYLRLRDRLASADAELGSRPIIPGIMPITSLKSV
RRQLQLSGAKLPARLEERLVAAAAGDEEANRDEIRKVGIEESTLMAERLIAEGVPDLHFM
TMNFARATQEVLHNLGMAPAWGREHGHDAVR
>A0A1V5RIJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium ADurb.Bin314|TrEMBL
MRISSIYRAGQPVISFEFFPPKTPEGERKLYESAAELKELHPAFVSVTYGAMGNTQANTL
RVVSEIRNRIGIETAAHLTCVAHSRGEISGILEKLAAARIENIVALRGDPPQGETEFRPV
ADGFRHASELVKFIRSCSRFGEAFDLIVAGYPEGHPECRDLRKDLEHLKIKVDAGANAVN
TQLFFENGFYFDFVERARKAGITVPIVPGIMPVTHGPQIEKFSKMCGTKIPGEIRRAIER
FGDDQDSIIRFGIDYATRQCRGLLDGGAPGLHFYTLNQSRATRKIYSNLGLAD
>A0A2W6VE77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MTSPTPISFEIYPPRSDDGLAALYDTIGELASADPQFISVTFGAGGSTRGRSLDVLTHIL
RETNVPPVAHLTCVGSSYAEATAIIREFLDAGITRFLALRGDPPAGVSEDDVFLGDLGSA
AELVQLIGRVQAEREPYAEEPVPGVPGAARVGRRERVQVAVAAFPNGHPRSAREGDDLDA
LLAKQAAGATSAITQLFFHPDDYLGFVDRARAAGVIIPILPGIMPITSPSRLRRVLELTG
DPVPTELAAALDSAPTPDAQREVGIAHAAALATEVRAGGAPGIHLYAFNNHATVLAVLRR
AGLIDARTTSTQGAPA
>A0A6I6VIV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. S34|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAIYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A7S7Q0H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. CCBAU 51765|TrEMBL
MTDVTTPATADGHLKRPAISFEFFPPKTEEMERNLWETIKRLAPLEPKFVSVTYGAGGST
RERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPVGGIG
TPYASHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDAGAT
RAITQVFFDNELYFRYRDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWFAAK
FEGLDDDAETRKLVAATVAAGQVQKLSKHGVDTFHFYTMNRADLVFAISHLLGIRAKSVQ
KAA
>A0A7X8EJK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistaceae bacterium|TrEMBL
MFIRDILGRTRPAISFEIFPPKPETPLETIFDTIGALRDLNPDFISVTYGAGGSSRDRTT
DIASAVQNRWGLTSLAHLTCMGSTPPEVEGVLEVLEQEGVKNILALRGDPRPEDEGNDGP
FQYASDLIKYIRRGHFSDFSIGAAAYPEGHAECSSPVDDLRYLKEKTDAGADFLITQLFF
DNEIFFSFMEKVRRAGIKVPVLAGIMPVLNARQIGRIVSLCGASIPPKFARIMSRYEHSP
QALAEAGVAYAAEQIIDLLSWGVDGIHLYTMNRPDVSGRIMGSLLSVRDTLTTE
>A0A1Q7PAQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium 13_1_40CM_2_62_10|TrEMBL
AVNVTDNTAAVMRAGSLSVCRLLYEMGHDPVMQITCRDRNRLGIQSDLLGAHLLGIRNIL
CLTGDYPTVGDHKDAKPVYDLDSVQIMQLVQGLNNGRDLAGNKLDGSTDFVIGAAVTPEA
DPVGPMLVKFETKVNAGAQFFQTQAIFHPELFNSFMRAVRKFKVRVLAGILLLRSAKMAE
FLNANIPGVAVPEEMIAELRAAGDRHALDVGVEIAVRTIKAVRPHCDGVHIMAIKAIDRL
PEILTKAVLG
>A0A078LU53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas saudiphocaensis|TrEMBL
MTSANRPSISFEFFPTKTEAGHEKLLTTARRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKTELRELLNIYKDAGIHRIVALRGDLPSGMGMASGELRYAN
ELVEFIRNETGDHFHIEIAAYPEMHPQARNFEDDLSNFVRKAQAGADSAITQYFFNADCY
FYFVERVRKLGVDTPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMDSIQA
FGTQVISEMCEKLLAGGAPGLHFYTLNQAEPSLAIWENLNLNR
>A0A4Q8UMY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. S39|TrEMBL
MTVSPTTSDGRRSGPTRIEIIPTEGIVERVASRVPLTTPITVTCLPHHGIERTLRAAVQL
SVLGYKAIPHLAARSLQSRAELTGILRDCDAAGIGEVFVIGGDRKRPAGIYESALPVLED
IAQYTGGRMRAGVAGYPEGHPSVGPVDVLDALLAKQHLASHVVTQMCFSASTILDFAALL
RREGVALPVWAGVAGSVPRAKLVSLGTQIGVGSSLKFLSRKGPLALKLLGGDRYSPDSLI
AGLESRPGSIAGVHLYSFNSLDSVPGGPDLAPVPSAALIPGAARED
>T1A5H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MTGLNDAMQVPPASGSRFPIPVSFEFYPPKTPEQHEQLERTVTRLRVHAPQFVSVTFGAG
GSTLSYTPDTVRALREVHGLEAVPHLSCMGGTRSEIAALLEQYRDIGCTRVVALRGDLPS
GMATSGDFRYAADLVRFIRSEHDRHFHITVAAYPETHPQAEDAHADVRHFVAKIEAGADN
AITQYFFNTDAYFHFVEDARRAGVSAPIVPGIMPVSNFAQLRRFSEQCGAEIPRWIVRRM
QAYGDDTASIRSFSADVVAAMCRRLLDDGAPELHFYTLNLAKPTEAVLERLR
>A0A2N7U9N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas endophytica|TrEMBL
MSTQEHPLGISFEFFPPNTDAGREKLVGVRDALACRNPRFFSVTYGAGGSTQSRTLDTVR
VVRESGITTAPHLSCIGSEKSQLRDLLRQYREEGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFEKDLENFVRKMRAGANLAVTQYFFTADAYF
HFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLETYGDDSHAIADF
GEEVISRLCERLLEGGAPGLHFYTLNQAEPSLKVLDNLS
>A0A495IXX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter gracilis|TrEMBL
MKITEHIANANGKTLFSFELLPPIKGQSIQGIYNAIDPLMELKPPFIDVTSLREDHIYKE
HENGLLEKLITRKRPGTVAVCAAIMNKYKVDAVPHLICGGFTKEETEYALIDLQFLGIDN
VLVLRGDARKAESGFVPTVGGHAYATDLLGQVVNMNNGMYLHDTGPTSYKTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGAGFIVTQMFFDNQKYFDFVNNCRANGITVPIIPGLK
PITVSKQLISLSKIFHIDIPEALSEAITDCKSEKDVKEVGIEWMIKQCKELVQFGVPVLH
FYTMGNPEPTKRIAQAVF
>A0A0M9ZHF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. AS58|TrEMBL
MTTFSFEFFPPGTDAGERTLWEAVRRVEALCPDFVSVTYGAGGSSRDRTVAVTRRIAAET
TLRPVAHLTAVGHSVAELRHTVGRYADAGIRDVLVLRGDPPGDPGGPWTPHPDGFTYACE
LVELVRSLGDFTIGVAAFPERHPRSPDWESDIRHFVAKCRAGADYAITQMFFHVEDYLRL
RDRVAAAGCAIPIIPEIMPATDVRQIRRFAELSGAAFPEDLAHRLEQARDDPDTAHRVGV
EHGTAMAERLLAEGAPGLHYITLNRSSAALDIHRNVRAAAGPSRVPSTSGMA
>A0A2M7WCA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium CG_4_10_14_0_2_um_filter_63_37|TrEMBL
MSSRALTPSHTPLPGLQGPVRIPDLLAHRRVVTVEVKPPKGCDVGSALAEVAPIADRVDA
VNITDSTLARMKISSIALAAIIQERFGVNTVFNFTARDRNLIGLQSELLGGWALGCRNLL
ALTGDAVAIGDHPEAKPVFEFNSVGLVKTVRTLNEGTDATGHPLEGKPHYGIGVAANPTA
PKLESEIKRLAKKVEAGAEFVMTQPVYEPQSLHRFLDLVAPLGIPVLLGILPLKSFKLAR
FLDEKVPGVHIPTDLLARMNKGDPEAELAQGTQEAMAMLDAARDRVAGFHIMPAGHTGVV
LALVDHLDRVGFRALPPPQ
>R4UL23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus subsp. bolletii 50594|TrEMBL
MTTNPLDRDGPVAELRDPGSIADRLTAVQPGEIAFSVEFMPPRDEAAEARLWRAARVFER
YRPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEERLLRAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTARG
>A0A2H9QWC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon CG_4_9_14_3_um_filter_38_12|TrEMBL
MDSFRCSLINTKFPITYEPDSPKGVLVENLPENIPEKVSAICVYNNPRGEPKLDPFVYGL
KLKEKCGKDIIVNIRVQDYSIPLFQSVLWGGHVLGIRNLLMVTGDCCSRSPFLIDVTEGI
TAVTEYLNNGYIMPGLSGKTKIHHNRYKENTSLTDNQQQMFEKFEGKTDFFVGAALLPAR
RKEPEIYQKKIDAGAQFFMTQLTYDSKNIIDFMEKVNPAKPVL
>A0A4P8SJ13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. SGAir0095|TrEMBL
MGLLEALKSKVLTADGAMGTLLYAYGLDNCHEEMNIIRPDLIEKIHHEYITAGADVIQTN
TYGANAIKLARYGLEDKVIEINEAALSIAKNAVGTGNQFILGSIGAIRGVRKSDVTLEEI
LAAIKEQAKILIEGKVDGLLLETYYDFEELSETIKLLRKETSLPIIAQVSMHEPGILVNG
MNLNDALKVLQDLGADIVGVNCRLGPHHTIQAFEGVELPDKAFLSAYPNASLLDIEEGRV
IYESEIDYFARAAVRLRNQGVRLIGGCCGTTPKHIEAAKKLLKSLDPIKVKDAVVQKEIF
IQEAEPSILEPLHEKVKRERSVIVELDTPRHLEIEAFVEGAKLLYSEGADIIMMADNSLA
SPRISNIAMGSILKLQHGIRVMPHITCRDRNLIGLQSHLMGLNALGFHDILAVTGDPTKV
GDFPGATSVYDVSSMELISLIKQLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTIEKIEEIYEATKHLSAPIYIGIMPLTSYRSAEFLHHEVPGI
KLSEEVLERMKACDGDKVKEAAEGIAIAKELLDTAAKYFNGIYLITPFIRYEMTIQLMQY
INQLDEQNKGVKANV
>F3AQN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 3_1_46FAA|TrEMBL
MKIIDRLKEDKIHISFEVFPPKTDAGFEKVIAATDAMAKLNPAFISVTYGAGGGTSKNTA
KIASHIKDDLGVVSLAHLTCASSTIEEVRDVIENLKENGIENILALRGDIPEGMPFPNGN
RFRYAYELIEEIRKHGDFCIGAACYPEGHVENEHKAEDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGINVPVLPGIMPMTSEKQMKRSQELSGTVFPRRFLALLDRFGSSAA
AMEQAGIAYATDQIIDLLSNGVNNIHIYTMNKPHVAAAIMNNLSEIIKA
>A0A1Q2MBA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limihaloglobus sulfuriphilus|TrEMBL
MSGKRLSQALKTRDKFVIVTELCSGPNCNLAPINKFMEAFRNSNGLDIPDEFDYVGITNP
QSPGGVANIDPDVILAHLRQNDLLGELDFIPHLSCKDYNSDALVSRLYGYRASGIESILA
LTGDKPTVAQGVFDLESIGLLNKMRELNNESYIKAKPDGLEKVNTFFAGAAVSPFKYTEA
SQMQQYFKMEKKIRAGAEFLITQVGWDWRKSAELMRYLKDENLDTPVLGNVYFLSTLTPA
PRLMHDRKLPGCFVSDEFFKKIISESVEDHIERAAQQVAMYKSIGAAGIDLGGVEDYQTF
IKILKRAAEIGESWEAYKDNLCWPAKKSWYLYYETGEKVQLSKPKRKFRQKNFDFMHEHI
INPESTVGKCLKSTMQVCGMDKAKGFCYSAFNGIEKPIKYWLFECEECGDCYLPENFSYC
TIGGCEKGLDNAPCGDSTEDGYCCNNLDRICIGEYIYKAAAATEGGLEKLRARSNKPRMP
ELEHSASIVNYILSKDHTVKCPIINIGEMVHASIPNTGEVMKALHKLDNWDTANSRELEY
IHSLIDQQARDGADYIAINLDAFGEDDPQLTAELMKKYVRLVRKWSHGVPACIDSSDDNV
LKAGLAEWYNTKQKVGVPLINSIKEHTIDEIMPLKKDYKFKFIGLLVADEKQVTSDDPIG
ELFKIAEKIFDAAVNRYGFKPDDIFFDTTVFPLAIDMPMMPGQSGFTYRAFETIKRIKTH
PQMKDCHCSLGVTNSVRDLPGRKIGVARAYVEVAMRYGLDAGIVNPSHKFGLKPADPELV
KLVEAFAKIDGDSENLNEAMKLMGEFCSNNRKAVK
>A0A1F8PBU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_50_9|TrEMBL
MSLQSKLESGKFVITCEVGPLKGTDITEVEENIEILKNKVDAANVTDQQSSVMRLGSLAV
SSILVNKGLEPIFQMTCRDRNRIALQSDLLSAWMMGIKNVLSITGDLPALGDHPQARAVY
DLDSVTLLHTIGRLNGGRDLAGNELKGKPSFFPGAVVKVESNTEASMELQLIKMERKVAA
GARFFQTQAVYDADHFAKFMKRAEKFKVPVLAGIIPLKTPGMAKFMNKNVAGVFVPDALI
QKMADAQDKAATGIQIAVDLIRQLKSLCQGVHIMAIGWEKRVPQIIQAAGL
>A0A6L6J602|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus aestuariivivens|TrEMBL
MTTPAVSFEFFPPRNLDQSFRLWDTARALAPLQPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETMQIVADYAAAGVHEIVALRGDAPQGQDRFTAHPQGFANSV
DLIEAIAARGDMTIRCGAYPEPHPESPDTAADVAWLKRKSDAGATSAITQFFFDADTFFR
FRDQCDAAGVTATILPGILPIQSWAGARRFAERCGTSVPAWAEEAFAHAGKEGEARLALD
VCVKLCEDLVAGGVDKLHFYTLNKPELVLKVCAALGVMPKDALPEVA
>A0A832WZD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp|TrEMBL
MLFNFREKLNSSKFLVTAEVSPPKGTRFSVPLEDARQLKGIADAINVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICVMTGDFPSCGDHPGSKP
VYDLDSVQLLQLVRKLDSSINFAGNRLDGGTSFCAGAVSGIDPEKPLQLIKLEKKVRCGA
DFIQTQAVYDVGMFEEFMEAISHLEVPVIAGLIPLKSLGMAEFMNRNISGIHVPEEIMLR
IKGAPDPVEEGLSIASETIKELMKLSRGVHIMPVGSHKNTPRLLSMAGISGK
>A0A4Y9ZA45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dentipellis fragilis|TrEMBL
MKLAEKFASSERPFYTLEFFPPRTDQGFGNLISRISRLAELKPIGVSITWGAGGSTRARS
LELAAVTQKDLGLDTIVHVTCTNMEMGVVDETLRAVKDIGVQTILALRGDPPRGKESWIP
IDPRFSHAIDLVTYIRTHPEFSDWFSIGVAAYPDGHSDHVLTEDEELGYLKDKVDAGADF
IITQLFYDVDNFLRWEGKVRERGIKVPIIPGIMPIQTYASFRRLTKLCGASIPESLEKDL
DAIKHDDSKVKEYGVSLAISMVKRLANEGGIRGFHFCTLNLEKSVQRIIESLDWARASSI
NQTPNRLIADTPGVVEFATNDQEHTVTPATATTSATSGLAMHAAREGEIGKGEVNSAATW
DEFPNGRFGDVNSPAFGSQDLWGGFSSLYSSTLSQWPRPKTVSDVTDICMRFLSSETTSY
PFSPSPLSTESQRILLQLKRLARLGWWSVGSQPAVDGEPSEDPVIGWGPAGGYVFQKPFI
EFFAGEDVVERLEKKVNENGKGWVDYLAANFEEEAFSIWTEWASLYPPKSQERELLEGIR
NSRWLINVTHHDYKDPEGLWNFLFEDTPEVSVATPTVLPRPQIFPRLLPKPPQPHPIPLD
RSGRWAERVYPRRDLAQEMDDLSDEENELEDITLDIKNRGYNSMIPIGKMFTQYEEKNDA
DDGSEGDDSHSSHPDSQASASDEEGDESEEEEEGGDLDADMEDLDEEPGNMTAETDPDDM
DDGEADFYDS
>A0A085VRD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLLTVARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALLTQYKDAGIKRIVALRGDLPSGMGMASGELRYASDL
VSFIREETGSHFHIEVAAYPEMHPQARNFDDDVKNFVHKAQAGADSAITQYFFNADSYFH
FLERVQKKGVTLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A7C9PI68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ideonella livida|TrEMBL
MNTATHPGAGLPVSLEFFPPKTPEGTAKLAAVRQDLYALRPTFCSVTYGAGGSTQDGTLQ
TVQAILAEGCEGASHFTCVGATRDSVRTRLAEFQAMGLKRLVALRGDLPSGYGAMGEFRY
AADLIAFIRAETGQHFHLEVAAYPEMHPQARSPQADVQAFAAKVKAGADSAITQFFFNSD
AYFRFVDEAHALGADVPVVPGIMPITNASGILRFADGCGAEVPRWIRLRLQSFGDDTASI
KAFGLDVVTDLCDQLRCAGVPGLHFYTMNQSVPVLEICRRLGL
>A0A2N8T4L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MKQSKELLMTSANRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRD
RTLNTVLQLDSEVKVPTAPHLSCVGDSKQELRELLNIYRDAGIKRIVALRGDLPSGMGLA
NGELRHASDLVEFIRAETGDHFHIEVAAYPEMHPQARSFEDDLTNFVHKAKAGASSAITQ
YFFNADCYFYFVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYG
DDIDSIQAFGEQVISEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1E4J919|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. SCN 67-85|TrEMBL
MSRIVGDITDAYSLEVSAKDIPALTAAAPRILRASTISIPYLAGQNNDARLAAARAVRGL
GFEPMPHLSARRVASLAELDSFIQRAVAEAGVERCFVIAGDPSTPTGPFADSSSLIETGV
FERAGIKVVGVGGHPEGHPIMSASDRWDVLARKCRSIEQRGMAPWIVTQFGFDADIVLAW
LKALRERGIEHPVRVGVPGPAGIAVLARYAALCGVSACASMWSKYGVSIGKLLGTAGPDL
FVDRLAAGLTQAHGKVSLHFFPFGGIAQSVRWIEQYRSRATVISR
>A0A378XQ86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oligella urethralis|TrEMBL
MNRIETEGSRFFSLEYFPPREQSARERLIDTTKQLLEIDPDYISVTYGAGGSTREGTEDT
VQMVSNLGCEAVPHLACVGSQPAAIREILDSYQAKGIRRIVALRGDLPSGMGLADSPLRN
AVDLVRLIREHSGDWFSIKVAAYPEMHPQAESFDEDLEHFVAKVNAGANMAITQYFYNAD
AYWDFVDRAQAKGVTIPIVAGIMPITNYSKLARFSKMCGAEIPRWIAKRLESYGDDVQSI
RDFGHEVVSRLCDDLRRGGAPGIHFYTLNQAEPVLKICRALQAQ
>A0A2G9VJF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loigolactobacillus backii|TrEMBL
MSLTDLFQKKTVFSFEVFPPKATTPAEKLQATLHNLQAIHPDFISVTLGAGGTGRYGATV
DIADMIQNQLGITAVSHIPGLYLSEDDVLNLLQKLAERNVHNVLALRGDRVSGREPLGVF
KHADQLTTFIKQNSDFDVMGACYPYTHKDATSGVADIQHLANKVAAGADHLISQIFFDNN
QFYNFREKAELAGINVPIEAGIMPVTNKRQIENITSVAGVPLPEKFTCMMERYADNKEAL
RDAGIAYAIDQIVDLVAQGVDGVHLYTMNNSYVAQRIWDATASLFQASATTTK
>A0A0V8ITN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter enclensis|TrEMBL
MSSPRRSDASPNLSDAAPVALSYELFPPRSPAAAETLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELIDRLLVETTLRPLAHLTCIGNTPQELAGIIGQLLDTGVRGILALRGDLPKD
GDRPVDGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPARHPESPSEEHDVEVLL
AKQRSGADFAITQVFFHPSQYEDLLARARRAGVAIPIIPGVMPLTSLRRVKRLGELAGLQ
PDTKLTDRLAAADTDLERLRIGVDATVDLANAALDAGAPGIHLFTFNEHQSALEVLDKLS
LPRHSRAGSRNAARAQLAG
>A0A0J5PAJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructobacillus sp. EFB-N1|TrEMBL
MIYLRKKHFFPLEVFPPRKNTSKESILPTLSSLNDISPDFISVTLGAGGTAQGNETIEVA
NLIQNQLHVPAVAHIPSLYRNQDQVDELLDQLAADNIQNVLALRGDPVDGLSPNGTFYHA
SDLVAYIDREYPNFDVAAACYPEVHQESPSVVADIEGLRRKVDAGADHLISQLFFDNQHF
YEFQERLALAGITVPVEAGIMPCTNKKQIERITKFSGVPVPKKYQKMLDRYADNPLALKD
AGIAYAIEQIVDLVSQGVDGIHLYTMNKPEIAEKIWDATKTIFEANQTKDRGAIELVH
>A0A3N2QRZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. R17|TrEMBL
MQLVHEQMTDPDADTACGEELDFLARSASIELTPRQILTTDDLSRWLAPGTAVYVPFLPK
ARYDDTVDACCQLRAAGLDPVPHFPARAVASAGQGQEWLERLGAAGVDKLMVIAGDNGDP
VGPFKDTLALLESGLLTRYPFALGVAGHPEGHPSADHPSLMQALQIKRDYAATTQTRMWV
TTQFAFEADSFTDWLQTAGDHLAPLPVYFGIAGPTKLRTLMAYAAQCGVGVSARALMRHP
ETARLLRSWTPDGLVEALAQYRVAHPLTLFKGIHLFPFGGLKRASRWLEDLRSETPDCAA
SPGRA
>A0A448RD70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sputigena|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYQNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVEACKNNADVKQVGIEWAIQQSKELKAAGAPVLHY
YSMGKSDNIVKVISEVF
>A0A0E2HCZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] clostridioforme 90A8|TrEMBL
MKTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTREDVLLILEQLKEQKIENILALRGDRVPDREPAGDF
RYASDLVEFIKLHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFKERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFISVMERYGDNPIAM
RDAGIAYAVDQIVDLVAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>A0A2G6MU02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacter postgatei|TrEMBL
MKTESRLEKVLASGQLAVTSEVGPPRGCNIDIVKEKANLIKDHVDGINITDNQTAMVRMS
SIAAGIAIKQMGLDPIIQMVARDRNRLAMQSDILGAYALGCNTMLCLSGDHPQFGDHPMA
KPVYDIDSTNMIKMVKDMRDEGIFQGGAEIKGAPRMFIGAAANPFADPFELRVMRLAKKV
AAGVDFIQTQCIFNTAKFEKWMKQVVDRGLDQKVAILAGITPMKSLGMAKYMKNKVPGMD
IPDEVIDRLSGVEKDKQAQEGIKMAIEQMQRLKECKGVKGFHIMAIEWEEKVPELVEGAG
LSPRPQV
>A0A3N2QVG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. R17|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQVVRDKLAEVNPDFFSVTFGAGGSTRDRTIDTV
LSLHKQGISTAPHLSCVGGSRESIAELLDLYKDNGINRIVALRGDLPSGMGAAGELRYAN
ELVSFIREHSGDTFNIEVAAYPEFHPQARSAEEDLKNFARKVDAGANSAITQYFFNADSY
FYFIDRLEKMGITIPVVPGIMPIVNYTNLARFSEMCGAEIPRWIRKQLEAYGDDSESIRQ
FGEEIVTRMCEKLLDAGAPGLHFYTLNQANASVSIWHNLGLAQRDKIAF
>I8RAM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus pentosus KCA1|TrEMBL
MNLRQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHQSYIQAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVRIAVTAREHADHPVYILGTIGGLAGDTDATVQR
ATQAEIAANVTEQLTALLATEQLDGILLETYYDLSELLAALKIVKGHTDLPVITNVSMLA
AGVLRNGTSFTDAIVQLHAAGADVIGTNCRLGPYYLAQSFDNLAIPAEVKLAVYPNSGLP
GTDQDGAIVYDGEPSYFEEYAERFRQLGLSIIGGCCGTTPLHTAATVRGLSSRNLVPHNA
PSHVAQAPTLVTTKSQHRFLHKVATKKTVLVELDPPRDFDTRKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTAIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAV
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TNVSTKSISRKLSYGCDYIITQPVYDLANVDALADALAADQIDVPVFVGVMPLVSRRNAE
FLHHEVHGIRLPKSVLERMQQAELDGNERAVGITIAKELIDGICARFNGVHIVTPFNRFK
TVLELVNYVQQKNLTKVQ
>A0A6B1G0H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineaceae bacterium SB0675_bin_29|TrEMBL
MANSDQTSAAGEWELHGGASRLRQVLEAGHFAVTAELNAPDSADPKDVYANVAELGDVCD
GINATDGSGANCHMSSVACCALMARAGYEPVLQMGCRDRNRIAIQGDLLGAAALGVRNVL
CLTGDDVSAGDQPEARRVFDFDALHLLRTAQIMRDHGVLLSGRKLTTPPEFFLGAAANPF
VPPQDLRHLRLAKKIEAGAQFIQTQYCYDVPVFEAFMRRARDMGLHEKVHLLVGVGPLRS
ERAAEFMRSRVPGVHIPDAVVDRLAKTPRKGKREEGIRICVEIIEEVKRIEGVHGVHIMA
YRQEEAVPEIVERAGILREKPKE
>A0A848ZLE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
LGGALLVKEMGGEPILQMTCRDRNRLALQADLLFAHSRGINNVLCLTGDSVILGDHKEAK
GVFDLDSSQLLATIRVMEKGNDLGDNKLDGAISFCAGAIVTPEANPIEPQLIKFEKKIDA
GAEFIQTQAVYDLDNFKSFMDYARQFPVKILAGIILLTSAPMARFMNKNVAGVFVPQDLI
DEMDAAPKGRKLEKGVEIAGRMIKRIHGEKMCHGVHIMAIGKEELVPDIMSAAGLI
>A0A7C5HC63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobaculum parvum|TrEMBL
MLVKEILDAKTEPVFSLEFFPPKKQDDWDKLFATISNLSPLDPSYVSVTYGAGGSTRERT
HNLVTRIQQQTGLTVVSHLTCIGAEKSEIESVLKLYREHGITNVLALRGDKPADVATLAE
ATKDFPHAIDLVRFIKANFPEMGIGVAGFPEGHPETPNRMQELEYLKEKIDAGADYIVTQ
LFFDNRDYFDYVERCELAGISVPIIPGIMPIMNKKGMARMCELALGSRIPSALLRKVNEA
KDDKEVAEIGIEWATNQVQELLDHKVKGVHFYTLNLSEATLKIFRNLKRG
>A0A7X1L6M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MTAKTPSKLEKVLAAGHFAVTSECGPPRGSDPTEIVEKAEIIKDHVDAINITDNQTSVCR
TCSLAVCIRLKTMGLEPVLQMVTRDRNRIALQSDILGAAHWDINNILCLSGDHQSFGDSS
KGQNVHDLDSMQLLQTVRLMCDEGKFLGGDDIKRPPQMFAGAAANPFADPFEIRVARLAK
KVAAGAQFIQTQCIYNLDKFEEWMKGVRDRGLHEKTAIMAGLTPMKSAGMARYMKNRVPG
MDVPDEVVKRLADTPKEKQAEEGIKMCIESIQRLKEVEGVRGFHIMAIEWEEKVPGIVEA
AGLYPRPEV
>A0A831VJS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSEYKSGSNLERVLKGGHFAFTGECGPPQGANVEKLREKARHLKGMVDAVNVTDNQTAVV
RMSSWAASLILLKEGLEPNFQMVCRDRNRLAMQSDILGVYAHGIRNMLCLSGDHQKFGNH
PQAKNVYDIDSMQLIHAVKTMRDEGKFLNGEQIDEPPKLFIGAACNPFADPFEFRVYRLA
KKIEAGADFIQTQCIYNMDKFREFMKRVVDMGLHEKCYILAGVTPMKSVGMARYMAKQVP
GMDVPDSLIKRLQGAGKGKVAEEGIKFAVEQIEEFKEMEGVAGVHLMAIEWEHRVPEIAE
RAGMLPRPKV
>A0A3S8W778|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC 01529|TrEMBL
MALGTASTRTDRARTVRDMLATGKKTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGEWVAHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSPDWESDTRHFID
KCRAGADYAITQMFFDPEEYLRLRDRVEAAGCATPIIPEMMPVTNVRQLDRLPQLSNAVF
PAELKDRILAAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHRQA
>A0A7C0Z3A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKITKLFDRGEFVITGEVGPIKGAVSRDWRVSPSCAQEAWHLQDFVHAVNVTDNQSAVMR
LGSLAASVGLKQRGIEPIFQLTCRDRNRIALQSDLLTAYSLGVDNVLLLTGDHIQLGDHK
SAKPVFDLDSVQLIRMAKGLQEGHDITGHEIENPPDMALGAVVNPNFEPL
>A0A7Z2QRS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. R84|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVERLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A0N8HIJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia sp. UCD-24C|TrEMBL
MSASEHPSGISFEFFPPNTEAGREKLKGVSDQLAALEPEFFSVTYGAGGSTRERTFNTVQ
SVSASGICTAPHLSCVGSDRGELREILAQYREQGVKRLVALRGDLPSGMGSRSELRYANE
LVEFVREETGDHFEIAVAAYPECHPQADNYHSDLENFARKMQAGADIAITQYFFNADAYF
HFVERARAAGIQQLIIPGIMPITNYTRLARFSDSCGADIPRWLRQQLESYGDDSESLQAF
GTEVISRMSQRLLDGGAPGLHFYTLNQAEPCLKVLENLGISSR
>A0A2C9ZT74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium kefirresidentii|TrEMBL
MSPRLSASAPLDYESEEESHVPERLALSFEVIPPRHDADAAKIDRLLEVLESYHPDYIAV
TSSQRSGWLEGTAAFIEKISQNTSMRPLAHLACTAGSRDELIGWINRLVDAGVRGLLALR
GDLPEGGMPEHYLQHADELVRLIRELESHQAARFAAGRLAVSVACYPSGHAESKNEDEDF
DVLLNKQRLGADFAITQLFFDAEDFLRFAQRAELAGVKIPLIPGIMPMTSLRRLERMGQL
SGLALPERVRTRLAAAKTPEEEYEIGMELTAQLARTIVAGGAEGLHIYTHNNPDITQDLL
SRIGVSNDEH
>A0A1F8MZ78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_53_26|TrEMBL
MTGQSFKEVLNSGKFVVTSEIGPPKGTNIEKMCHHIDILKDKVDAINVTDHQSSVMRFPS
IGGCLHVKEQGGEPILQMTCRDRNQMALQGELLLAYTRGIRNVLCLTGDSIVVGDHKQAA
DVFEFDSVQLLRAVHHMESGKDLGGNDLDGAVKFCAGAIVTPEAHPLEPQLIKFEKKVEA
GAEFFQTQAVYDLDNFSKFMKHARQFRVKVLAGIVLLVSARMAKYMNENVPGIFVPKNLI
DELASVPKGGALNKGIEIAGRMIAELKNSSVCDGVHIMAIGKEEVVPDILAAAGLSVDNT
THVPGSGGR
>A0A1Q8YL58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax antarcticus ANT.BR|TrEMBL
MTASSVIPVSIEFFPPKTPEGVEKLRVVRQALYALKPEFCSVTFGAGGSTQEGTFNTVRE
ILAEGVAAASHLSCVGATREGVRGQLALLQAIGVKRLVALRGDLPSGYGAGGEFQYASDL
VTFIRTETGNDFHIEVAAYPEIHPQAKSAESDLKAFATKARAGADSAITQYFYNSDAYFR
FVEDADALGVQIPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIKAFG
LDVVTDLCEQLRAGGAPGLHFYSMNQNTATLEICSRLGLQK
>A0A3A4SW18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSTLEKILTAGHFAFTGELGPPRGSNIEAIRKKAEPLKGMVDAVNITDNQTAVVRMS
SWAASLFAISEGLEPNYQMVCRDRNRLAMQGDILGASAHGIRNMLCLSGDHQQFGDHPQS
KGVFDIDSTQLIQMVKKMRDEGQFLNGQEIDGPPKIFIGAAANPFAEPFEWRIYRLAKKI
QAGADFVQTQCVFNMEKMREWVKRANDMGLTEKVYILAGVTPMKSLGMARYMKSKVPGMD
VPDHVIDRLKGVEKGKQAEEGIKMACEQIAEFKEMKGIAGVHLMPIEWEHKVPEIAERAN
MLPRPNV
>A0A3A4RX83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSFQKRLSSDEFVVLAEMDTPKGVDISNLVTNARRIKGRVDAVIIPDMDNGVMRMSSMGG
GVLMHQQGMESIIHVYCRDRNRMALQGDILAAHVLGIQNLIVVHSEGMDKGDHRDAKTVN
DLDEVELIKGIKSLQDGVDMAGFELNGSPKMTIGCTISPYADDSALEKELELARKKVQAG
AQFIISPSVFDIDHFSRFMGKAKTLGVPIIPTVFLLKSVGIARYMATYEPGAHISEDLIK
RIRKAPDRELECIRIAGETIKELKRFAQGVKIQTLGWEHRLPAILDQAGM
>A0A523QUS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MQLKRKFDAGEFAILAEIEPPKGVEISTMVTNAMRVKGKIDAFLVPEMSNAVMRMSSLGG
AMILKGKGVETVIQFNCRDRNRIALQADLLAAYGCGITNVMAVTGEDPSFGDHHQARSVY
DINLLELLQAITGLQNGKDMAGIELSGSPEFLVGSTVYAGAPGKSPELEFEGMNKKIEAG
AQFFITPPLFDLSAIQPFLKRVDLNQTKIIPTVLLLKSLGMVRYMARNVDHVFIPDSLIQ
RIQKAPEKVRECVRIASEMVTTLKQEGFGGVLLATIGWEHKLPEILEKT
>A0A3A4S6Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSLKSKLNAGKFVILAEMEPPKGVDVSQMVQKATKVKGAVDAFVVPEMSNAVMRMSSLGG
AMVLRNKGMETVMQANCRDRNRIALQADLLAAQACGIQNVMAVAGEDPSFGDHHEAKAVY
DINLPEMLKMIQSLQAGKDMAGIELAGSTDFTVGSTVNAFLSGEDLDREIHEMEQKIEAG
AEFFITPPVFHMDALHPFMEKASKFDVKIIPTVLLLKSLGMVRYMARNVKSVMITDDLIN
RIQNAGDKVRECITIASELVKDLRLNQFNGVHIVTIGWEDRLPEILGGMGV
>A0A3C1S8N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLEKVLKAGHFAFTGELGPPRGADAHEVKHKAAFLKGNVDSVNITDNQTAMVRMA
SWAACLILIQEGLEPNFQMVCRDRNRLAMQADILGAYAHGIRNMLCLSGDHPKFGDHPTS
MGVFDIDSMQLIQMVKKMRDEGKFLGGADLHGAPKMFIGAA
>A0A3A5AUV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MDFQKCLSTGEFAVLAQMNTPKGVNVSEMVNNARRIKGRIHAVVIPDMDNGVMRMSALAG
GAIMRQQGLEPIIHVYARDRNRMAIQGDLLAAHVLGIQTLVIVRGEEMAQGDHVNAKCVD
DLDEIGICGAIKCLQNGVDLAGSELDGNPGFLVGCTIKPWADERALDAEIDSARKMVDAG
ARFVLCPPVFDVDRFSTFADKTKGLGAALIPTVFLLKTVGIARYMATYEPGAFIPEHLIK
RMRQSKNREMEGFVIAGETIKSLKSLAGGVQIVTLGWEHRLSSILDYAEI
>A0A241WKI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4654|TrEMBL
MSKRIPVSFEFFPTKTDVGAEKLRVVHQELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYASDLVA
FIREHSGDHFHIEVAAYPEMHPQAESFDQDIQNFITKARAGANSALTQFFFNPDAYFYFV
DRLQKEGIDLPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNQTEPNRQLVLDLGLA
>A0A353H7Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSKLEKILSGGQFSVTAECGPPKGTSAKVIRKKGELLKSHCDALNVTDNQTAIVRMS
SLSGSVILKQIDVEPVMQMVVRDRNRLAIQSDILGAVALGIRNVLCLSGDHQKFGNHPTA
KGVYDIDSMQLLQTLKHMRDEKKFLSGDDISGEVPLFLGAAANPFADPFEFRVTRLAKKI
KAGADFIQTQAIFDVPKFIRWMDMVRDRGLDQKVHILAGVIPVKSVGMARYMKNNVSGLS
VPGELVDRMADAKDAKEEGVKICLEIIEQIKEIKGIHGVHIMAVAWEDIVPGIVEKAGLM
PRLAGEV
>A0A3B4BGP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Periophthalmus magnuspinnatus|TrEMBL
MVNQVQRSDGSWGSRSDSSAASNSGGDSSKESSRCSTPVLDGTRADRLRDKMRRRMESGD
NWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSIMIASTAV
NYCGLESVLHLTCCNQSKANITAHLAKAKHLGLKNIMALRGDPVGEDWEEEEEGFNYAID
LVKLIRSEFDDYFDICVAGYPTGHPEADSYEDDLRHLQEKVAAGADFVITQLFFRAETFL
KFEEDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRNY
GIHQAVEMCRVLLDSGRVPGLHFYTLNREVATMEVLRQLGLWQEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSRDAL
LQMWGEELHNEQSVFEVFTNYIAALPNCKGHKVLCLPWNDEPLAPETNLLKNELEKINQR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVN
YHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLNSCLWQVLEDMFELLRLDLGPLDTKESEE
PQDPALNQEAVPE
>A0A1Y6C1W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobacteriovorax antillogorgiicola|TrEMBL
MSARLSFTEVLSQKIALLFDGATGTELYNRGLFINRCFEEANLSNPNLIRELHEDYVKAG
AQVLSTNSWGANSFKLRTHNLHDKTYEINKKAASIAREAIGPDGYVAGSVGPLGVRIEPW
GPTSFEEAKNSFKEQIKGLVDGGVDVISLETFGDISELQQAILASRELNPKMPVIAMITI
NPEGQMPVGTPAEWAIKKITEWGVDALGFNCSVGPQPIMSAVKKIQNTTRCPIVVQPNAG
LPKQVDGRTIYMCTPEYMAEFTKHFLEAGVQFVGGCCGTSPQHIKSMAQAFRHQKAMRHS
EGDLSPEFSSIEHTSSGDICAEGCERVPLEKKSKWAQKIANGQMVSSVELLPPSSVLPDK
ILERSKQLKDAGVDAINIPDGPRASARMSAILTSVMIEQKVGIETVLHYTCRDRNLLGMQ
SDMMGAHAIGLRNMLLVTGDPPKLGNYPDATGVFDIDAIGLTNMVHRLNGGLDLGGRPIG
EPTALTIGVGVNPVHRDFDYEMKRFKYKVEAGAEWAITQPVFDLRALYKFIDHIEKENIK
IPIIAGIWPLLSFRNAQFMNNEVPGVVIPDEIMKRMAEPQSPEDAKKVGVEIAHTMVEEL
GDSVQGIQVSAPFGRADLALKVLGK
>A0A6L9L3Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma terrae|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFTREETEDFLIDLHYLGID
NALVLRGDPAKPFTTFKAKENGYTYASELVEQVANMNQGIYLHEEDTPLAPSNFCIGVAA
YPEKHFEAIDHETDFQYLKLKIDKGADYIVTQMFFDNQKYFDFVKRCREAGITVPIIPGL
KPISTRKQLQILPKIFHLDIPQDLAKSIEACENDQQARQVGVEWSIQQCRELISQGAPVL
HFYTMGKADNIMKIAREVF
>A0A850EXL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus agri|TrEMBL
MKPDLRSAWGNKVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEEVHRSYIQAGAVL
LESNTYSANYDKLSKFGLESKVEEINRTGVRIARRAAGEAGYVVGAVGSIRAGKRANLSS
SELKKYFTQQITALLEEDVDGIMLETFYDVEEMHLALKTIRKHSSVPVICQFAMDDTART
LDGLTLPEAFRILEQDGADIIGFNCRTGPMGIKRALGTLQGSLTLPVSIYPNAGIADYVD
GQYKYGASPEYFGQMAMTFAEMGSRIIGGCCGTTPQHIAEISKALAGYEPEALPEPTVKP
VERITIAEHLSDETGLGGGEPTLVDLVKERHTVIVELDPPRDLDINKFMKGAEALRRAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGVNH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKANFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDPELIANIGKATAHLSVPVFLGIMPLASGRN
AEYLHNEVPGIQLSEEVRNRMSGLEGEAGRAEGVAIAKELLDAATEHFNGIYLMTPFMFY
DMSVQLLEYVWQKSGRKLSPLFR
>A0A7X6D5M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lonarensis|TrEMBL
MALGIPSVRHDHARTVRELLAAGERSYSFEFNAPRTEKGERTLWEAIRRVEAVAPTFVAV
TYGAGGSSREGTIRATERITTDTTLTPVAHLTAVEHSVAELRNIIGRYADAGIRNMLALR
GDPPGDPMGEWVRHPEGVSYAAELVELIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVN
KCRAGADYAITQMFFDADDYLRLRDRVAAAGCDTPIIPEIMPVTSVRQIERLSQLSNATF
PADLADRVHAVREDPGAVRSVGIEHATRLCERLMDEDIPGLHFITLNRSTATLDIYRNLG
LHRRPVTTGDGGPAH
>A0A0D7WXV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus terrae|TrEMBL
MKPDLRTVLDREIIVGDGAMGTFLYQLGFPVNTSYEELNITSPDVISDVHRQYVQAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
VELARNYDQQIDALLSEGVDGILCETFYSLDEVRIALRGVRKYSNIPVICQFAVDQVGRT
QDGFSVAEAFTVLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAASFVELGTRIIGGCCGTTPEHITAISKALNGLQPPPLAPREIRT
DAPVIVAEPEQIAREGERGNGRNASEPNIVELVKERHTVIVELDPPRDLDITRFMQGAQA
LKAAGADALTLADNSLAVTRMSNMALGHLVSLETGLRPLIHIACRDRNLIGTQSHMMGFD
ALGIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKANFVV
GAAFNPNVKHLGKAVQRLEKKIASGADYIMTQPVYDRELIISMAEQTRHLEVPIFIGIMP
LASGRNAEYLHNEVPGIQLSDEVRARMSGLEGAEGRAMGVTIAKELLDTAMEHFNGIYLM
TPFMFYEMTAELTSYVWQKSGRVQAPLFRL
>A0A6N3QF17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella flexneri CDC 796-83|TrEMBL
MSFFHASQRDALNQRLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A803VXI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ficedula albicollis|TrEMBL
MLGLDIGFFNHLLPTPAVPALCRDPCTDHTPSAPLCRALTMVNETQHTCSASSSSRSDGG
SSSGSESSKDNSRCSTPVLDLDRHERLREKMRRRQDAGDRWFSLEFFPPRTANAAVNLIS
RFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDI
TGHLQKAKRLGLKNIMALRGGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQPET
FLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIR
NYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHP
KRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRE
ELLKMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDELERVN
RRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELR
VNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQW
AKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLNSPTQQ
>A0A7W3J0F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides ginsengisegetis|TrEMBL
MGTGRGRSMAELIGGGERSFSFEFFPPKDAEGEERLWRAIAALEPYQPTFVSVTYGAGGS
TRDSTVRITSRIAHETSLTPMAHLTCVGHTREELECILDTYAEAGVHHVMALRGDPEGGP
RGEWTPTPGGLTHADELVALAHRRGDFRIGVAAFPEGHPSAKSLDHDADVLVAKARAGAE
FAVTQMFFRAADYFALVERVRDRGVDIPIVPGIMPILNLSAIRRQGELIGAEVPAEVVER
ISAHDGDAAAVRAEGIAVAAELCEELLEGGAPGLHFYTLNFSKATLEIFAALNVTC
>A0A7J9QIE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilaceae archaeon|TrEMBL
MTIRYEANPPKILPDGDIDKSIKKFIERIKDISKKCDAIHLTENVLGFHRVSPLEVGKII
KKEIPDLPITVSLRVRDKSEEEISEFVDNCIEIGFSGILILMGDPSQTGKVDSGEIPSLT
VKKLKEKNIDSKIDLYLSVSNKPNFSKLGKKTDAGPRGFMTQVVQNVEQVQALADNLKEF
SVIPIILFPSEKNEKSAKFLDLDLELYSQEFEELLKKSHEITGDVLLTSPNDFTGLNEFL
GKTSF
>A0A6J4GKD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium bizetiae|TrEMBL
MKVTEHIENAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
VMALRGDAMKDEQYFMPKAGGNDYAIDLVKQISLLNQGKYLHEVMDADNRANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFKFVEKAREIGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDQCKSNAEIRQIGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASHLF
>A0A2W6SYA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citromicrobium sp|TrEMBL
MMSPTLEQMRAAQTALEAPLFAGLPGDVEVSFEFFPPKNESMAESLWQSVQTLAPLGPRF
VSVTYGAGGTTRQRTHDAVIRIERDTDIPVAAHLTCIEASREEVDAIARDYWAHGVRHIV
ALRGDPPQAGTRYTPHADGYANAAELVAGLKAIAPFDISVAAYPETHPDSPDLAADLDNL
KRKLDAGANRAITQFFFEPDCFFRFRDAAAGAGIDAEIVPGIMPVLSFASVERMSGLCGT
AIPAWMADLFTGLDERPAARQLVSATIAAELCRKLYAGGVRQFHFYTLNRAELSYAICHM
LGLRPKEMP
>A0A1G0CRN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium GWA2_60_18|TrEMBL
MNKPLFSFEFFPPQTPEGAEKLAAARRQLALLRPEFMSVTFGAGGSTQERTLETIRQMKA
EGHNAAPHLSCIGATRESIRELLFAYRDMGISRIVALRGDLPSGMAGSGEFQYANELVSF
IRAQTGEHFHIEVAAYPEFHPQARSPREDLVNFKRKVTAGANSAITQYFYNADAYFRFVE
EARRMGVTVPIVPGIMPIVKFSQLARFSDGCGAEIPRWMRKTLESYGDDSASIQAFGLDV
VTQLCERLLAGGAPGLHFYTLNQAGPTLEIWKRLGL
>N1MQE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium japonicum BiD32|TrEMBL
MTLNDPVAPLYADLAGDCHVSFEFFPPKTEKMEAQLWSAIETLTPLNPKFVSVTYGAGGS
TRERTHNTVARIARETSLAAAAHLTCVGASKAEIAEIADAYWEAGVRHIVALRGDPPEAG
GTFEPHPDGYKGAAELVEGLMQRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFTPDAYFRFLDKTLAAGITADIVPGIMPVSNFAATQRMAAMCNTQVPSWMGRLF
EGLDDHPASRQLVSATIAAELCRSLYGGGVRDFHFYTLNRAELSFAICHLLGLRANISLE
TAA
>A0A4R6K1K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2527|TrEMBL
MTGFQVICEVEPPTRPDLKKVRHQIGVMSPIADAFLIPDNHIGRATVSSVAVANEVQLMG
ARGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDDPREGGRTSQLTVRTMIEETRA
TGFPGCGPFEVGATARLGRVPRWKAEADFLYLQVSFDVDELLRWRDSVALDIPVYAGVMV
LASAKMAHNLASVPQLAIPDRLVEAVERDRDAGVEAACEQVLRIRDSGAFDGVHLIPVSR
YRQVAARLEPEL
>A0A2A2I3E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tamilnaduibacter salinus|TrEMBL
MESQKQFKRRFSFEFFPPKTDKGEEKLQKTRDRLAELNPDFFSVTFGAGGSTRDRTLETV
TRLHSQGISTAPHLSCVGATRESIAELLDLYRENGVERIVALRGDMPSGMGGAGELRYAN
ELVEFIREHSGDYFNLEVAAYPEFHPQAPTAEADLQNFVRKVKAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNYSKLVQFSDMCGAEIPRWIRKQLDAYGDDTESIKQ
FGEDVVTRLCEQLLDAGAPGLHFYTLNQANASTHIWRNLGLDQSKRIAF
>A0A0G3LSZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas translucens pv. undulosa|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKTYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQASDALSDLRHFKAKVEAGADGAITQYFYNADAYFHFVDA
VRKLGVQVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQALGDDGDAIREFGADLV
AALCQRLLAGGAPALHFYTLNLAKPTISVLSRLE
>A0A249MU10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium xenophagum|TrEMBL
MTLNDPAAPLYADLAGDCHVSFEFFPPKTEKMEAQLWSAIETLTPLQPKFVSVTYGAGGS
TRERTHNTVARIARETPLAAAAHLTCVGASKAEIGEIADAYWEAGVRHIVALRGDPPEVG
GTFEPHPEGYKGAAELVEGLMQRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFTPDAYFRFLDKTLAAGIKADIVPGIMPVSNFAATQRMAAMCNTQVPSWMGRLF
EGLDDHPASRQLVSATIAAELCRSLYGGGVRDFHFYTLNRAELSFAICHLLGLRAAASNG
GTA
>A0A7G9S4S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter denitrificans|TrEMBL
MSATLLTGSAPTRARFSFEVFPARSGAAALALGNSVQHLSAVGPDFISVTYGANGSNRDA
SIDLLTYLRNHTDALPLAHFTTVSETREQLKTQIHRIMDAGVHDFLALRGDPPHGLDEQS
PEITGSLTSVELTELIAEVRAERPAFTSVGRTAVAAYPNGHPLSRSRSADIDWLIAKQEA
GAQLAITQLFFRAEEYLSYVDEARRAGLTIPILPGLMPVSTSAQLRKVASLAGRPAPVEL
ERAMEEAGGFAPELGVEHTIQLARELLAGGAPSIHLYTFNRHEQVLAVLEELKLLEA
>A0A7X7IQL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pirellulaceae bacterium|TrEMBL
MPEHAPLIFRDIVTDDRFHYGAEVVTTRGLSPADSPSSVVGLAEDLLADPRIGWISVTDN
PGGGPMLPPDWLAGRLSAHRHRMVLHLTCKDMNRSGIEAAAWRYASEGFDNLLAITGDYP
TGGFGGTAEPVFDLDSLGLIHLLHLMNEGLQVPGRRGALETLPATNFFIGCVVSPFKRHE
RELMPQYFKLIRKIAAGAEWVLPQLGYDMRKFHEIKLLLASRRLEVPVVGNVYVLSGFVA
KLFHSGKLAGCVVSDELLETCQKQAASPDKGQKFFHEFAAKQLAVVKGLGFTAGYLGGMA
KAETFGKVIDLAESFGENDWRDFLPEICYSQ
>A0A7Y5YIQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. C1C7|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLSQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGANSAITQYFFNADSYFY
FVDRVQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQNIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQADASLAVWNNLKLPR
>A0A2E4V8Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MSDFLHQIERRILVGDGGLGTQLRLRLPSNIPCLDACNIDPIFRNFVYEIHADYGRAGAD
IIQTXTYGANQLKLDLQGYGNQLESINLAGVQLASQAATEISSSQNRQVFVAGSVGPLET
NPLEDELSITEVRQAFTAQMEVLVSAGVDLLILETFTDLRQTKIATKLAVKFGLPVMVQI
SGISKGVVSDGTDVRVFAQTLSQLGASVIGLNCRGPHDLLLAAEKIARVTDIPLSVQPNA
GTPRIDQGKISTTYSVSPDHFSGFIKKFLSLGINVIGGCCGTTSEYISVIRENTDGYVPA
RRQTXIFVFPDNQKXSKSKISPNPIKQIFETNDRIVSVEMRANTFPQLRAMIKVSKNLAD
LEVDLFDVPDNAGATVNIGAIGTAFKLQQXSNIPTLIHWTTRQRNLISIQSHLLEAWALG
IKGVIALSGDHPKVGRFETAKIVTDVRGSVQLMELLKRLNQGTLIDGTSLGEPCXFYVGG
GFTITKNLKPQLKHLRRKVERGAKFIYTQPVYDLSTAEDVYQSIKNEGLDTKILLGILPI
TSLRSISFLQDNLGMYIPSIVVKQFQDIDDPKDQLLYGLSIARDLVSRLSEQNHFSVDGI
YIIPPSRMNWANKQVAITQLVQSFRKRKTEER
>A0A807EIE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. NRF60-BP8|TrEMBL
MKPIELSFEFFPPKTADGVDKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPAADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAAAATRTICERLAV
>A0A6G3YU08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. SIO1D8|TrEMBL
MVANVPSQKSLTGSQFQAAIRAGDFLVTAEVMPPKGGDPDHMVTMAQKLHGHVHAVNITD
GSRAVMRMSSLAAAVILHQQGIEPICQMACRDRNRIALQADLLGAHALGIRNILALTGDP
VKAGDHPQARSVFDLESVRLLKLIRQLNNGFDLHDRPLTSQPTTLFAGAAVDPQSPSWSG
LQRRFAKKIEAGAQFFQSQLIDDFERFEKFMDQIAAGCDRPILAGIFLLKSAKNAQFINR
NVPGVSIPDHIIERLAQASEPLQEGIRIAAEQVRAAKELCQGVHMMAVRREDLIPEILDL
AGVELISGKANDSPIGIGLTSIKYS
>A0A496AF83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MHNNAESIGNMTSQPKDKQNFMDAIHQRVLVCDGAIGTELRKRISAHLPCIDACNIVEEH
ADRVLGIHQAYVAAGADVIQTNTYQANREALTQQGYESELEEINRIGVQLARRAASTECF
VAGSVGQIPFQIEEVSESTVPPSSNTIRRHFQEQMDTLVDEGVDLLILETFVLQKQAEIA
TQQALTYGIPVIVEISGVSGGTLGTGVDVRVFAQEIEQLGAHAVGINCRGPHDLVQAMEL
LAPVIKCPLVVQPNAGNPRVEQGEIAVSYTVDSDNFSDYVKKLINLGANMIGGCCGTTPE
YTAKINAVVAGSPPIRRQHRVFILPKSSPSHQSLRDNPVEEVFKTREKIVSVETRANTFP
QLRALLKEAQVMAATGVDLFDVTDNSGAAVNIGAVATAFRLQQSTNIPTLIHWTTRSRNL
ISMQSHLLEAEALGIRGIVALSGDHPKAGPYEAASLVPDVRGAVQLMKLIGRLNQGELAD
GSSIGEPCGFYYGGGFTIAENLEPHVKHLTNKVAEGAKFAYTQPVWTFEDIERTHRATNH
LGIKVLYGILPLTSYRSASYLRDNLGLYIPQLIVDKYRDLGDTAGNDLGMQLTLDLVKEI
RNQDNIPIDGIYLIPPARLNWKNRRAVISTIVETYR
>A0A126RJ34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. TKS|TrEMBL
MTLSFPSVEEARRALDAPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIQTLTPLAPKFV
SVTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKAEIDEVVDAYWEAGVRHIVA
LRGDPPEAGTKFEPHPDGYKGAAELVEGLVKRHPFEISVAAYPETHPDALSAQSDIDNLK
RKLDAGATRAITQFFFEPDTFFRFRDTVAAAGIDAEIIPGIMPVSNFAAVQRMSAMCNTD
VPGWMGKLFEGLDDLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPATLEKTA
>A0A3S9MT32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus periodonticum|TrEMBL
MSSQSPPLSFEVFPPNPAVGNEKIMAVLKEMQDLAPHFISVTASNRKFNIEETTVRLADF
IYNDLQIPTIAHLPAVYLTKEMVSDTLEALDRVGVHKVLALRGDIVPNMEPKKDFTYATD
LIEYIKEQAPHFEIIGACYPEGHPDSLDRVSDIKNLKKKVDAGCSSLVTQLFFDNERFYD
FQERCTLAGIEIPIHAGIMPILNRNQALRLLKTCENIHLPRKFKTILDKYEYNPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSNTAHQIYQATHTFFNK
>A0A2D6CZN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MKSGSNLEKMLAAGHFAVTAELGPPKSADAKAVSKKCRYLKGIVEAANITDNQTAIVRMS
SIAGGVLALKRGVEPVVQMTCRDRNRLAMQSDILGAHALGVRNLLCLSGDHQKFGNHPTA
KNVFDIDSIQLIQMVKEMRDDRLFMCGEEIRNTPKAPIVEPRMFIGAAANPFADPFAFRV
VRLAKKVEAGADFIQTQCIYDMDRFREWMRQVVDRGLHERTAILAGVTPLKSAGMARYMR
DNVPGLSVPDSVVERIAGAKKGSDEGIAFCVEQIEELKEMEGIAGVHLMAIEWEQKVEQI
LEATGLLPRPKVEADEAPEEG
>A0A1V5MYC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin408|TrEMBL
MKVTEHLKNNSKTLFSFEILPPLKGKSINELYSQIEPLLEFKPAFVDVTYHREEYIYKKR
DNGLLERKSIRKRPGTVAICAAIQHKYHIDAIPHIICGGFSAEETENALIELNFLGIENI
MALRGDPVKSEKKYVPEEGGHHYASDLIEQIKKLSRGEYIDDELLNQTPLDFCIGVAAYP
EKHFEAPNMNTDLKYLKHKIDMGADYIVTQMFFDNSAYFKLREMCKENGIDVPLIPGIKP
ITSKSQIYEIPKTFHIDIPEELFNAVEACKDNNEAQQIGIEWAIEQSKDLIKNKVPSIHF
FTMSKSMAVRKIAQAIY
>A0A260AJV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 06-412-2C|TrEMBL
MSEESVRGRASRGFVTNTPSIVDRLRTEPNARIPFSVEFSPPRDAAAEARLWRAVREFEQ
LAPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRG
ITNILVLRGDPPGDPLGDWEKHPDGVEYAEELVRLVRDLGDFHVGVASFPEGHHRADDLE
QDTRCLVGKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDAEQGAKPIIPEIMPITSLRSV
RRMLELSGTTLPSSLDEKFTRAAGSGPEEDRAAVREVGIELATNIGERLISEGAPGLHFI
TLNFARATREVLCNLGLAPARV
>A0A415YEM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium AM10-38|TrEMBL
MKISEILKNKSTISFEVFPPKNKEGNISSIYSTIEGLAKLSPDFISVTYGAGGSTKGKTV
EIASVIKHEYGIESVAHLSCISSTKEDIKYECERLKEAGIDNILALRGDYPADAADFDPE
NLEFHYASELNKFIGEHFKGQFCLSGACYPETHQEADGFKKDLEALKKKVDAGAEYLVTQ
IFFDNDYYYRLVREARKIGITVPILAGIMPITNAKSLIRTTKMCGCTIPYQLSTMIEAHY
DNPEAMKEIGINYAAQQIIDLITNGVDGIHIYTMNRAETAQRVFESIPAVLKELN
>A0A147HBG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudacidovorax intermedius|TrEMBL
MRLPISFEFFPPKTPEGAVKLRAVRAQLRERAPQFCSVTYGAGGSTQAGTFATVLEILEE
GNDAASHFSCIGATRDTVREQLQQLKAMGVRRLVALRGDLPSGYGIGGEFQYASDLVAFI
RAETGRDFHLEVACYPEVHPQARSPQADLQAFVTKVRAGADSAITQYFFTPEAYFRFVDE
ARRAGAEVPIVPGIMPITSSTQLMRFSDACGAEIPRWVRLRLQSFGDDTASIKAFGLDVV
GALCERLVVGGAPALHFYTMNQAAPTLALLDRLGGAA
>A0A2T4TZJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methylomirabilis limnetica|TrEMBL
MKIVDVYGTGKVGLSFEIFPPKTEAGEILLFAAIEALMAYRPSFVSCTYGAVGSTRENTL
ELTARISKTFGVTTAAHRTCVGSTIEEILRWLEEAADLGLENIVALRGDPPKGQAEFEKP
EGGLAYANELVTLIRQEFRHFSIAVAGYPETHQEAPSPAVDLANLARKVKAGADAVITQL
FYDNRDFFDFRRRYEEAGIAVPLIPGILPVLNLGQVQRITSMCGAKMPASFLTELEAHRD
DPDGQIGVGVRYAIQQCRELLDAGIPGLHFYLLNKSEATFQILQALKLSG
>V5FR84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Byssochlamys spectabilis (strain No. 5 / NBRC 109023)|TrEMBL
MEKITDKIAALPPDANFFSLEFFPPKTQMGSANLQARLERMAQALRPLFVTVTWGAGGTT
AAKSLELAEICQRQLQLTTCLHLTCTNMDRKLVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKEFKYAVDLVRYIRKVHGDYFCVGVAAYPEGHPGESVQDPQSPEHDLPYL
IEKTTAGADFIMTQLTYDIDAYRKFEDLLRNHESGVFKTIPIIPGLMPIQSYNILTRVTK
LSHVKVPDDVMSRIDKVKTDDDAVKRTGVDIVSEIVDKMKDLPCSGPRGFHFYTLNLEKS
VSFILERCDLIPPSTDAADDDGDADGVVIVEAPKDATETEIKTRSFTRRRASSINSQPHN
RLIVDKPSIPSDGSSRGSITHETAALSAGLPALNPPPRSTTLQISEGLGSLGREATWDDF
PNGRWGDARSPAFGEIDGYGPSLHVSAAVARRLWGYPVSRDDISTLFRRHVSGELHMVPW
SEGGAEEDSGGLNAETLTIRSELLKLIEKRGWWTVASQPAVNGVRSDDPTYGWGPQKEGF
VFQKPFVEFFCPNKDYQTVIKPLLQKYGDEEFAWFATNAAGEFESYVSSQSNGDVSERDQ
LNNGVNAVTWGVFRGKEIITPTIIEEVSFHAWGEEAFRIWDEWRRIYPRGSPTERFIDET
KNDVWLVCVIGQRYGAGTEPGSKEEEDETKMLWRVLAGEQ
>A0A2N1QYK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetae bacterium HGW-Spirochaetae-9|TrEMBL
DIATVPHIVGGLAERLDVEDLLIDLHYANFRDIFVVMGDDRYAPASIGGQAAHTTASHEG
YEHAGDIVKHISQLNAGKYTPPAEGKPTDFTIGVAAYPQKHFAAPNPETDFQHLVEKIQA
GAKFAITQMVFEAQPYIQLVRRLRELGLDLPVLPGIKPILKASSLDMIPRTFFVDLPQGL
VEALRDARSPEEERRVGIDWTTRLCGELLDAGAPGLHFFTMGRGAGTGWILDALFGPKGG
VA
>A0A4Q0QKR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium vignae|TrEMBL
MSGAMTDATTPGQANGQDGHLKRPAISFEFFPPKTEEMERNLWETIKRLAPLEPKFVSVT
YGAGGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDAIVDRYHEVGVRHIVALRG
DPVGGIGTPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKA
KVDAGATRAITQVFFDNDFYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRNGTTV
PDWLAAKFEGLDDDAETRKLVAATVVAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLG
IRAKTAQKAA
>A0A2B0U113|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKSHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDTAMKYFNGVYLITPFLKYEITEHLVKYVR
EKQDVKEGIN
>A0A7X2P7D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bilifractor porci|TrEMBL
MKITDLFERGEFAVSAEVGPPKGIHIEEMIEDAKKYLGGVDAINVTDCQSSVMRVGSLAV
CKELKDAGMNPIFQLACRDRNRIALESDLLSAAMFGIDNVLALTGDHTKMGDHPQAKPVF
DLDSVSLLHTMCVLESGKDLGGNDLVGEPPKFAKGAVVSPCSDSVDAQLVKMEKKIEAGA
EFFQTQAVFDSEKFIRFMERAKQFGKPVMLGIIIPKSAGMCKFMNNNVAGISVPDSVLEE
LKADKEKTKAGITGVEIAARIIRECKPYCQGVHIMSLGWESKIPSLLEQSGLAR
>A0A2A7HQG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVIEINRAAVKLAKASVTEKNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIASMKRAIANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKTKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISEELIDTALKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0V1IAU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella pseudospiralis|TrEMBL
MAIILQSALLVCISVYCLMIFFYSNNYVVFFPILCYPTGHPDASSYEEDLLNLKAKVDAG
ADFIITQLFFDEMHYFKFVNDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSKIVIPDSVL
TTLESIKENAEAVRNFGISFAVELCRKLLNAERHVVPGLHFYTLNQEKSTRSILEQIGLW
KESPVRMLPWKKHPVHSVRCREAVRPIYWNTRPKSYLCRTRDWKQFPHGRWGDLGNPAFG
DLKHYLFSCIDQMNDSCALDMWDKELSSFEHVRDIFCNFIARTPNRHGHTVRRLPWNENH
SDPAVDVLKDELIYYNSNGILTINCQVAVNGLPSNDPIFGWGEANGYIYQKVDDAQCILI
SLVYCINIIV
>A0A841QD85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter lovaniensis|TrEMBL
MVSTDNYDLRHIAFKHGREFEKCINGLPSRRFDTPMPVMSFEFVPPGTRMMAQRLWRCIR
YLAPLSPRFVSVTYGAGGTTRTGTVSTVLRLKRETDLVPAAHLTCTGATRRDVDDLARRY
WAAGVRHIVALRGDPPTGSADDPPQSGGYAYASDLVAGLRRIADFEISVAAYPETHPAAL
SPQADLDNLKRKLDAGATRAITQYFFDAETYLRFFDRCLAAGITAPIIPGIMPVSDYGQI
ARFSALCGVTVPDWLTHLFEGTVENPELRRIIASIVAVEQIRTLQAYGINEFHISTLNRS
DLTYAIAHILGARPTEQHAADNRLQCSETAEITDGQNAPTDCDTTGQTQEDAPPFMLRTQ
FG
>A0A7S4GH31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eutreptiella gymnastica|TrEMBL
IFFREMPSTSDLATAVRGPPRCVSAVKVGDIIWTEDATEGQLVKYITEFSGSLVELTLEN
AAGVESKVTYNATLEVGCQEAPTVAELLKNKDPNQITVSFEYFPPKTEKGVENLMNRIGL
MRKADPIFCDVTWGAGGGTSDLTLELCTNAQIKWGVNANMHLTCTNMEKEKIDMALEGCK
KVGIRNIVALRGDPPVGQTEWKAIDTGFSCALDLVKYIREKHGDYFCLSIAGYPEGHPTV
IADDGKCPPEAFAGEMAYLKEKVVAGGDLIITQLFFDVDIFLSFCAECKKLGIEVPILPG
IMIITSYGGFKKMAGFCKTWIPADLASKMEEIKDDEAAVKEFGVQYAVDMCKKLIDAGHK
HLHFYCLNVEGPTFAVMERLGLPVPGQ
>A0A164F3M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIHISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7S4FYJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eutreptiella gymnastica|TrEMBL
ATMPRIIDKIKELTADTKLFFSVEFFPPKTEPGVINLYDRMERMALLRPAFVTVTWGTNC
STKDLSLDIGTAAQNLMGLETLLHLTCTNTPTETLLEILNSARANGIQNIFALRGDPDKS
SKKNTGELKYAIDLIKLIRQHHGDYFGIAVAGYPEGHEESSSYEEDLENLRKKVEAGASL
VITQLFYDINVFLKFVQDCRAIGIKCPIIPGLMPIHSYSAFVRCLPLMKTVPHDVLDALE
PIKYNDEAVKDYGVRLLVDMVRKLSKHGVRGFHFFSLNLERSITRIVDELDLLDEQVQRE
LPWRKSANPRRYAAEEVRPIFWANRPKSYLAKTMAWDDFPNGRWGDSRSPAFGECDHHHT
RLLLGSRVGKTVWANVNSVAEVISIFRKYIRGEIKSLPWFESSLAAESKLITEKLDKINS
LGFLTINSQPSVHGVPSTEQSVGWGPVGGYVYQKEYVEFFCSPWDLSILLEVLNKDEFKF
VSYMAVNSKGDDSRMNVTSVNAVTWGVFPGKEILQPTVVDPISFGVWKDEAFALWLAAFT
DRAVVTLQDDPPPAVFQEIHDTWYLVNLVENDFVKGDLWTVFERVQQHPDFRPPKLEDEP
DQKGKFDKKKLINRYFSDEKVPILDDPDDDLDDDPDDGD
>A0A2C1S0R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEMKEGIN
>A0A1S9TTI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVTPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7X0ETV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea muscovyensis|TrEMBL
MALGRPSVLPDRVPTVRELLAAGGRSFSFEFFPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERLAHGTTLTPVAHFTAVDHSVRELRHLVGRFADAGVRNILAVR
GDPPGDPAGEWVRHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTEYFVR
KCRAGADFAITQMFFQAEDYLRLRDRVAAEGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPGVAARFEAVADDPAAVRALGIDHGAELCQRLLDEGAPGIHFITFNRSSASREVFQRLS
HAPAVTV
>A0A436MWF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.002.02.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A0F5R7F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. D9|TrEMBL
MSTPTLKDKLLSRQSGIITYGMTPPKNTHPAEKVREIADKQIERLQGIGLDGLVLYDVQD
EAQRTDKDRPFPYLASLDPTAYYRDYLQQELGLPAVIYHCVAGGSRSELEEWIHQNRDEQ
RYSVFVGASSSRQQVQVKLPEAYRLGTSLNEKLMLGGVVIPERHRGKGDEHLRALHKQES
GCAFFISQATYDVEASKSFLSDYYYHCRDNGIGMAPILFNLAPCGSAKTLEFMKWLGISI
PKWLENELIHSHDILDKSVQLSRETFRELYQFGLEKGIPIGCSIESVSTRKVEIEASIQL
VKDIKSDMRR
>A0A524A649|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MTNTLKAGSNLEKILTAGHFAATGELGPPQSADPEVIREKANYLKGYVDSVNITDNQTAV
VRMSSMSVAVMLLEMGIEPNMQMTCRDRNRIAIQSDLLGASALGIKNLLCLTGDHQTFGN
HPTAKNVFDLDSMQLLRMVKDLRDEKKFMCGDPVKGVEPRFFIGAAANPFADPFDFRPYR
LAKKIAAGADFIQTQIVFNVPKFREFVKRCGDMGLLDEVYLLAGVSPIRTFGAARYMANF
VPGMDVPQEYVDRMKSAVEGIPKEEKARRREASEREGVQICVEVIQQVREMPGVAGVHIM
AIEWEEAVDEITKQAGLQPRPTMD
>A0A2N4XWE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Baumannia cicadellinicola|TrEMBL
MSLFHIHHREILNHNLAERQGHINVSFEFFPPRTSEMEEYFWHSIHRLSKLKPKFVSVTY
GANSGDKKRTYSIIKEIKERTGLEAAPHLTCIDTSPTALQEIVQEYWRSGIRHIVALRGD
LPIGSSRQDMYGLDLVVLLKKVGDFEISVAAYPEVHPEARNAQSDLINLKKKIDAGASRA
ITQFFFDIESYLRFRDRCLVAGIDTEIVPGILPVFNFRQLQRFAAMTNVKIPHWMSVMFD
GLDQDIETSKMVGASIAIDMVKILIREGVKDFHFYTLNRDELTYAICHTLGIRSESRNTP
VIS
>S7U0Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp. X2|TrEMBL
MRICDLIEQKTPFVSLEFYPPKEREQWGSFFEEAEKLKAVAPLFVSVTYGAGGSTQDNTL
EIAARLKNQIGYEPLVHLTTVGATEERIAAFLDALTNSGIENILALRGDPPRGCDFAPDN
ERFQHASDLVTFARERFPGLCVGVAGYPQPHPQSPTVAEDLRWTKFKVEKGADFIVTQLF
FDVRQYFDFVERLRSMGITVPVIPGILPIMSLASIRFILSLCGASIPGSFYLELEAADKK
GGSEAVREIGMRFAIDQCRRLIDGGAPGVHLYTLNKADACLHIAGELNI
>A0A4R0S546|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKCGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A800A2L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
EPVFQMTCRDRNRIALQSDLLNAYVMGIENVLCLTGDYVTLGDHPEAKPVFDLDSVSLLQ
AARGLEQGKDLAGKELKGAPKFFLGACVTPGADPVEPQLIKMEKKVKAGAQFFQTQAIYE
PKKFEAFMKEARKFGMPVLAGIVLLRSAAMARFMNRNVAGIHVPDELIEEMDQAENKLQK
GVEIAARLIKEMKDMCQGVHIMAIGLESKVPAILDAAGL
>A0A7Z9K9Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAKIPDLANNGSSSLKIICDFSPPRGGTPSLIGDLDGLNPDIVSVAYNPGKSVRVNPVAA
AAWIKANTKQDVVFTLATRDMNKVAIQSLLLGAQLLGLQNIVIVEGDGLSNRDRERFKAV
YDFQPTSLIESVRDMNQGKDFRGLKLRVATDFSVGATIDMGRPSDSEIPLAVRKAQTGAQ
FFLAQAEFDPSVIARFRADFESHFDKGHAPPVFYGVQILAEDGIIFGNVPQGTRSELESG
RSGEEIALELIQNLMDQGVRTVYLVPPIFRGGRRDYDSARRVIESARRLAS
>A0A6H9IAA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTKPSDPALSFEFFPPNTPEGAARLREVRARLAAFAPEFLSVTYGAGGATRDKTLATVLE
ILAEKHTVAPHLSCVGATRESVRELLALYRGHGIRRLVALRGDVPSGMREPGDFRHASDL
VAFVRAETADWFHLEVAAYPEMHPQARSPRDDLEAFAVKVRAGADSAITQYFFNADAYLR
FRDDARRIGIDVPIVPGIMPIANFTQLARFSDACGAEIPRWIRLRLASFGDDIEAIREFG
VEVVAAMCRRLLAEGVPGLHFYTLNQSAAAVRVLEAIGLARG
>A0A7C3AYC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MDAENYIAISGQESIPVARLLDPVRIRERVNGRLKERVNTLSQAILDPSTFCVTWEQIPG
RGALETQQGELIDNARKAAKSGKIHGMSVTDNPGGNPALSTEMLCTEIKKLGIEPLVHLA
CRDKNRNEIESMLHGLTAAQVRNLLILTGDFPANEAFGGKSKPVFDLDPIHVLQLIEKMN
AGLEHEVMRRTMTLTPTEFFAGACVSPFKKTEAELMGQYYKLKKKIEAGAKFIIIQVGYD
ARKFHEILQWLKVNGYDIPVLANIYILPLGTARLMNSNGIPGCVVTDKLVAELAEEAKAD
DKGRASRLLRAAKMYAIAKGMGFAGAHIGGHGVTYKMVEYIIDKGEELAPHWQELVAEFD
FPQENGFYFFERDPRTGLNTNNPAMRPLKPSKPLMYRFSRLAHKLLFNPKSIILKAFQRI
APRIDSSPRMKRTFGYFEHLAKVALFGCMNCGDCALTDVAYLCPMSQCPKNQRNAPCGGS
YDGWCEVYPNERKCVWVKAYERLKAYREEDEIGDHIVPPCNWELFETPSWLNFALGKDHS
SKSVGIKPPEKKSLKKKTTTD
>A0A6I1ZP92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKTKSNLERILEAGYFAVTAQIGPPRNTEPEAIRGKANLIKGYVDAFNVPDGESAVVAMA
SWAACLIGKQEGLDPIVQMTCRDRNRIALQMDILGISTFGVNNILCLSGDPVSFGNCSEA
KSVFDLDSIQLIRMVKGLRDEKKFENGEPIAGREPRLFIGAVTNPFAEPTEHEVIRLGEK
VAAGADFIQTQSVYHIKKFERWMEMVRERELPKKVKILAGITPLKSVAIARYMKTKLSGV
DVPDELVERLRKATTREQVRKEGIKIAVETINSLKEIEGVAGIHIMAIEWEEVVPEICEA
SGLYPRTSLEELGRQ
>A0A7X4AHB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSFREAMARGEFPVSLEITPPRASKPAVLLRRARLLEACTVTVNVIQRPDRQSSLEAALE
LQREGLEPIWHLATGGRPIEEVTADIARAQRARLGHVLCLRGDHAADTPGTRVTDAIAVV
REQAPGMAIGAALDQYRTDERTDRILAGKLRAGARSIWTQPVFELAPLLRSAGFVKAIEP
EAHVVAMAMPLLTPESLDAISERLGIPAPAELRRRIEAGEEEAWGAFEETLATLARVDLV
DAVAIMTYRADPPPGTAERIVAALQRAGIGEAAGAATDR
>A0A7C3BRY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTNLEKVLESGRFTVTAEVGPPKGASPTVVRRRGELIRNYVDXVNVTDNQTAVVRMS
SWAGCSILRTLGIDPVMQIVCRDRNRIAIQSDVLGAIGLGIGNILCLSGDHQRFGNHPSA
KGVFDIDSIQLVQTLKNMRDEKKFICGEDVSGEVRIYIGAAANPFADPFEFRVARLAKKV
KAGADFIQTQAVYDVSRFRKWMDMVCERGLDEEVHILAGIIPIRSVGMARYMRDYVAGVT
VPDEIITRLEQAENTKEEGLVIPLEIIEELKEIPGVHGIHIMAVGWEDIVPEIVERAGLL
PRPVL
>A0A8C8CED3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
MVNQVQRVEDTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGFVFQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRN
YGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVNR
RGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAESLE
PPRLFLGLGVWPN
>A0A7V2W3J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSLKSKLESGKFAITCEVGPLKGTDITEVEENATLLRDKVDAANITDQQSSVMRLGSLIT
AYIVLQKGLEPIYQCVCRDRNRIALQSDLLSAWVLGIKNVLSITGDLPQLGDHPEAKPVY
DLDSVTLLRAIKGLNDGHDMNGNELRGKPDFYAGAVVKVDSDTDASMELQIAKLEKKVAA
GAKFIQTQAVYSADSFARFMKRIEKLNVPVLAGVIPLKSAGMAKYMNRSVSGVMVPDDLI
QKMTDAEDKKATGIKLCADLIKQLKPLCQGVHIMAIGWEKNVPQIIQEAGL
>A0A7V2QLB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MINSLFEEKLSSGEFVVTTEVGPAKGADTADLVHHIDLLKDRVDAINVTDHQSSVMRFPS
LGGCLLVKEHGGEPILQMTCRDRNRLALQADLLLAYSRGITNVLCLTGDSIDVGDHKEAK
PVFDLDSVQLLKMIRTLESGTDIEGNELKGVPRFYIGASVHPEADFVEPQLIKFEKKVSA
GAQFFQTQGIFDLASLRRFMQYAAQFNVKILAGIIVLASARMARYMNDNVPGIIVSQAII
DELADVEKGKGLQKGIEIAARLIKTIKDENLCHGVHIMAVGNEGVVPDILEAAELVSVSP
>A0A179SRH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metabacillus litoralis|TrEMBL
MSFLEDLKSKILIGDGAMGTMLYSHGVDRCFEELNLSKPDDVKRVHQAYIQAGANLIQTN
TYGANDIKLSRYGLEDEIRQINKTAVEIAKRAATSSTYVFGTIGGVRSFKKSAHTLEEIK
RNFREQLFILLNEDVDGLLLETYYDLEEMKTVLQIAKKETNKPIIANVSLHEAGVLQDGT
ALTDAFSTLEELGANVIGLNCRLGPYHMIQSLEEVPLLESAYLSVFPNSSLPALNEGRLV
YESDEGYFKESALKFRDQGVRLIGGCCGTTPKHIQAIAEAVGHLAPVTDKKVRVPKQVQV
NITSSNTDTLPPLQEIVKEKRSVIVELDPPKKLGMNKFLEGAQALHHAGIDALTLADNSL
ASPRVSNLAAGILAKEKTGGRALIHITCRDRNLIGLQSHLMGLHSLGLSDVLAITGDPSK
IGDFPGATSVYDVSSFDLISLIKQFNEGVSYSGKPLGEKTNFSVAAAFNPNVRHLDKAVV
RLEKKIAHGADYFISQPLYSSQQIVDVYEETRNLKAPIYIGIMPLTSSRNAEFIHNEIPG
IKLSDSIREKMAAAGTDKEQARQEGLAIAKDLIDTAFDLFNGIYLITPFLQYDLTVELTN
YIHEKEKQLAERKITHV
>J6F727|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichosporon asahii var. asahii (strain ATCC 90039 / CBS 2479 / JCM 2466 / KCTC 7840 / NBRC 103889/ NCYC 2677 / UAMH 7654)|TrEMBL
MKITDKLAKAEREGRPFWSFEYFPPRTAQGLQNLYDRIERMRNLGPEFIDITWGAGGKNA
DLTSSLVQVCQETIGIETCMHLTCTEMPKEKVEWALAQAKQFGCQNILALRGDPPAGSST
WKPTPGGFVHAVDLVKYIHKEYPGDFCVAVAGFPDGHPETPPTPEGHHQEMLWLKEKVDA
GADFIFTQMFYDVDILFNWVKEVRSYGITVPIVPGIMPIQNWQKFQTWVQRENIKVPEHW
YEALNPVKGDDEQVRAVGTKLVGEMCRAILANEECGIKGLHVYTLNLEKGARMLLEELGM
NPNREQVAPLPWRPSLAANRRQESIRPIFWANRVESYLSRTSDWDEFPNGRWGDSRSPAY
GDLDGYPVAINVQPADAENLWGQPKSEADVRELFARFCRGELKKLPWSSQPPASETSIIS
ENLIKMNERGYLTINSQPAVDGAPSDDKVHGWGPAGGYVYQKAYLEFFVRPELLSQLIKR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGNQWANLYPEGSESNKLIHKIMDESYLVNIVANDFKDGLAIFEPFLLDQPVEA
>A0A1Q3XF56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium 67-32|TrEMBL
MSSSLSPDAAPADAAPVFSLEFFPPRDIAAQERLVRTAKQLQGLHPHFASVTFGAGGSTR
DGTMLAVSMLQKLGYEAAPHLSCIGSTPESLRDILYTYRQAGIRRLVALRGDMPSGMGDM
GELRYARDLVDFIRKETGDWFHIEVAAYPEMHPQAQGPEADLDRFVEKMRAGADSAITQY
FFNADAYFDFVDRATAKGVLAPIVPGIMPITNYTQLARFSDMCGAEIPRWIRLRLASYGD
DRASIRAFGHEVVVELCQTLLDGGAPGLHFYTMNQADATQAVWKELER
>R5UCX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ruminococcus] gnavus CAG:126|TrEMBL
MKIIDRLREDGIHISFEIFPPKTDAGYDKVIRAAEEMAGLKPEFISVTYGAGGGTSKNTA
KIASYIKHDLHVESLAHLTCASSTKDEVRSVIASLKEQGIENILALRGDISEDMVFPSED
RFHYAYQLVEEIRRHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSARQMKRSCELSGTVFPRRFQAILDRFGDSPK
AMEQAGIAYATDQIIDLLANGVKNIHIYSMNRPEVAAAIMHNISEIIQC
>A0A1X1W7A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium iranicum|TrEMBL
MQFGPCGGVRPDGQCEMRAGPCVFPDVVPWEGLIPEPRAVSAPLVLTDFSSLPFDLDDMT
ATAAALSGTCDAVLVGEHQNRPDFPPVLTASTLLDSGVEPWITLSCRDRNRVVLEQELRG
LQLVGVQTVLCVTGDGRAYDVRPDVTQTFDLDGPRLVSLAASLAMTTAVPETPTAPPVSQ
RPQRLVHKQRAGAGVAVLNHVSTPAMVAQFMAAAREAGLTIPVLAAVAVLTDEASAAALQ
GLPGLALDDAVVRSILTAPDPREAGISAAVDEARALLGIDGVVGVNISGLASGAGTRVGA
EIKAEVGQRIREWVRSNG
>A0A3D3WSA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIIEILKKTRPISYEFSPPRTADGIPAVLEALDELKVYRPDFVSVTYGAGGSTRAFTEE
ITVQAKKVAGVEVMAHLTCVGQTKEEIHGVLERLDAAGVENVIALRGDPPRGETEFVPVA
GGFPHATDLLSHIKANFKFGVAAACYPEGHTESVDLDADLDYIKLKVEKGADFLVTQLFY
DNRYYFDFVERAKAAGIDVPIVPGVLPVLSSAQVRRFTTLCGSTIPSDLGKLLDKYADDD
SSARDMGVEYATAQVRELWDQGVPGVHFYVLNRSYSVSRILDNLALPGHQRED
>A0A556QEE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium godavarianum|TrEMBL
MRGTFAPTRLSASAPIDRVGEDTTQQRRRTRTALSFELIPPRHGADEGKLDELIAGLAAY
RPDYVSVTSSRRSDWLTGTAALIARVAETTNLRPIAHLACTAGTREELVTWIRTLIDAGV
RGFLALRGDLPETGMPADHLQHATDLLNLIQDVEDEEAFRLAAGKLALSVACYPSGHAES
KNFDEDLDVLLSKQRLGADFAITQLFFNAQDYLDFVEVARLAGVRIPLIPGIMPMTSLKR
VQRMGELSGIEVPECVARTLAQATTPEEEYELGMQMSARLANTILDAGTGGLHVYTHNNL
AVTQDLLSRIGIPQRADHSPQ
>A0A2G6DDW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MLKDKIKNKQSGILLYGLTPPKLSYGKERIGQISQKQIKRINALDIDGVILYDVQDEISR
SGKERPFSFLQSLAPEVYAKEYLHVDKPKIIYRVVGKYKRENFCDFLANKDVNFSVFVGT
ASKDQKVNLSMDEAYKLRHEIRKDLILGGVAIAERHKIKKDEPKRIFNKMQNGCEFFVTQ
AVYDRDNGREFLDDYVSFMKKKNHPLAPIILTLTPCGTLKTLEFMKWLGISIPKDFEEDL
KNSSDFLGKSVKFCQENFKFLYDYGKKIGVPIGCNVESVAVTRFEIETSVELLRSIKKIM
NENK
>A0A2E7SB78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MVKVTASLSKAIREPFFICDYSPPKSGVMAVNVIYPDTADFVLVNSSPGLSVRASSSMVA
AYIQSNAIADTIFTIVTRDMNKLALDSLILGGSIMGLRNVVVVAGDRFRMDRNQRPSQIN
DYRSTDLIRSIVHLNQGIDCRGVKLDSPADICVGSVLDLSTGLDKEVSLVHKKIVAGAEY
FIAQPVYEMETIDKFYELYRNRYLEDIEVPILWGIQIPDVNSISLTMFPDWVEDALNDGE
DPVPVALQMYESFRRRGLTDMYIVPTIYKGGHRNYSSANMFMSAAKQI
>A0A3A4VNG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTTRLEQILLSGQFAVTAECGPPRGANAEVIKKKGAALKGYTDAVNVTDNQTAIVRMSSV
AACAHLLQMGIEPVMQMVTRDRNRIALQSDIMGAYSLGIRNILCLSGDHQTFGSQPDARN
VYDIDSMHLLNTVKKMSDEGTDMSGYKLNVAPEMFIGAAENPFADPFEYRVIRLAKKIAA
GARFIQTQCVYDLPRFKEWLKMAEERGLLEKVYILAGVTPMKSTRMAKYMANKVAGMSVP
EAVIKRMAGVPEDRAAEEGIKICTETVAELRETKGVAGIHLMAIEWESVVPEIVEKSKLY
PRPA
>A0A2G6CZF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MNTQKQFKHRFSFEFFPPKTPVGMEKLQAVRDKMAEKSPDFFSVTYGAGGSTQERTIETA
LSLHKQCIDTAPHLSCIGVTKESLTELLDLYKENNINRIVALRGDLPSGMGAHGELRYAN
ELVAFIREHSGDYFNIEVAAYPEFHPQAPSAEQDLLNFKLKVDAGASSAITQYFYNADAY
FYFIDRIEKLGLNLPVVPGIMPITNYSSLVRFSDMCGAEIPRWIRKQLESYGDDSTSIRK
FGEQVVTEMCETLLDAGCPGLHFYTLNQAEPSLTIWDNLNIDRMLDKKVF
>A0A3G2HRL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes aquatilis|TrEMBL
MSNKQTLSLEFFPPRDIAAQEKLVRTAKTLMGLNPAYVSMTFGAGGSTRAGTVDAVALLQ
KLGFDVAPHLSCIGTAPAQLSEMLDNYRDQGIRRIVALRGDLPSGMGGDAGELRYASDLV
AFIRENYGEHFHIEVAAYPEMHPQATGFGDDLAHFVNKVKAGAHGAITQYFFNPDSYFSF
VERVQAQGVTIPITPGIMPITNSSQLLRFSTMCGAEVPRWIRLRLADFGDDRASIRAFGI
DVVARLCQDLLDGGAPGIHMYTLNGADASMAILPNLTWR
>A0A1F9QUZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium GWA2_61_42|TrEMBL
MKFTERLKAGTKVYSFEFYPPKTAEDTARLFNTALELKALSPDFVSVTNSSSGVTPYRTV
ALCGVLKAQFGLDVVAHLTCLAHTRAEIAEICDGLKKMDITNILALRGDAHNVASGALRR
DYDHASQLIADLKQTGGFSIGGACYPEKHPEAASLEADISRVKEKVDAGAEYLITQLFFD
NAFYFRFLEKAAAAGVSVPVLPGLMPITGYKQMQNFTKLMQVSVPAALRAGIERWDGDKD
GMFKFSVEYASAQAQELLKGGAPGLHLYTLNRSRAAIAILKNVKAAL
>A0A2G6DDH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKQYIEAFFSSFTLETTPGTAKKIDDYRKLVRQGEKIYVTFLPGSDFNDTIDVATRLRRE
GFDPIPHIAARSVPDQKYLENIIQRCVEEAGVDRFLLIGGAVDNPVGDYHCTAQILETGL
MDKYGVKSIGLAGHPEGSPDMPDKDIQEALDFKNAFAERTDAECYLVTQFCFEAGPIIAW
DKALQASGNKLPIHIGVPGLASIKSLIAHSKACGVGASMRFLTKQAKNISKLLLVSAPDK
LCTDLAEYKATDPNCGIAGMHLYPLGGLQKTADWAYAVRDGKFTMHADQRGFDV
>A0A3N5XYN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKISDLIKTRGKSLSFEFFPPRTPMGEDQLLKRINTLKTHSPSFISVSQHAGPNTLERTK
HTIGILRKETDLTIMPHITCADPARAELIEVMEYYKNIGIENILALRGDPAEYGANVFDG
VNHYCHASDLVKFIASHQNFCIGVGVYPEGHPESDNLGIDTSRVKNKIEQGADFCISQMF
FENFYYYQMLDRFIQDGINIPVIAGIMPITDFQKVEYYAEQGGVEIPVPVVAKFEELDDP
NDVLKAGIDFATEQCLDLWENGVRCFHFYTLNRDEVISRILGNLALTFSQTP
>H9MZH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Danio rerio|TrEMBL
MVNQRADVGWHSKSDSSGASNSGESSRESSRCSTPVPDADRTDRLRDKMKRRIESGDHWF
SLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYC
GLESVLHLTCCNQTKEKITDHLNKAKRLGLKNIMALRGDPVGEDWVEEDGGFNFATDLVK
HIRHEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIVTQLFFRAETFLKFV
KDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIKQVIEPIKDNDAAIRNYGIQ
QAVEMCKVLLASGEVSGLHFYPLNREVATMEVLRQLGLWAEDPRRPLPWAISAHPKRKVE
DVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQM
WGEELMSEESVYEVFTNYITGQTNRSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGVL
TINSQPNINGKASSDAIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYQI
VNVQGRNITNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYE
DESPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFALLDSSQVPQQEANEL
>A0A7M4G0Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocodylus porosus|TrEMBL
MVNESPSSGSSGSRSDGGSSSGGESSKDSSRCSTPVLDAERHERLREKMRRRQEAGDRWF
SLEFFPPRTANAAVNLISRFDRMAVGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYC
GLETILHMTCCNQTKEELTAYLHKAKHLGLKNIMALRGDPIGEEWEEEVEGFNYAVDLVK
HIRCEFDDYFDICVAGYPKGHPDAESYEADLRYLKEKVCAGADFIITQLFFRSRTFLQFL
KDCQAIGITCPVVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVE
LAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKM
WGEELTSEESVFEVFTCYISGEHNKNGHKVTCLPWNDDPLATETNLLKKELEKVNRRGIL
TINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLRVLRKYELRVNYHI
VNARDENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKGEAFALWIEQWAKLYE
EESPSRMIIQYIHDNYYLVNLVDNDFPLDSCLWQVLDDTFELLSAPTQC
>A0A6G7GXH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kuenenia stuttgartiensis|TrEMBL
MKSGSNLEKLLRDGKFAVTAELGPPRGADRTVIEKKAVMLKGYGDAFNITDCQTAVVRMS
SIAAGRIVLDSGVEPIVQMTCRDRNRIAIQSDLLGAAALGAKNVLCLTGDHQKFGDHPMA
KGVFDIDSIQLIQIVKALRDERLFQCGQELKAGGPAFFIGAAENPFADPFKYRAARLGKK
IKAGADFIQTQIIYNVNKFKEWMKMVTDMGLHEKTYILAGVAPLKSKGMAKHMKYNVPGM
DVPDEVMERMDAAAEAKRGKEEGIKICLEVIEQVREIKGVAGIHIMAVEWEEAVPEIVRQ
AGLYPRPSV
>A0A511Y2I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium rhizosphaerae|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINNLGRGKYLHDEDQICDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELITAVENAKNNEAVKQIGVEWAIAQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A1L1P8W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga intermedia|TrEMBL
MNLPISFEFFPPKTPEGAEKLRAVRQQLYARQPLFCSVTYGAGGSTQEGTFGAVREILAE
GVDAASHFSCIGATRASVREQLAQLKGMGVKRLVALRGDLPSGYGLGGEFHYASDLVAFI
RAETGEDFHLEVAAYPEVHPQAKSPEADLKAYATKVKAGAHSAITQYFYSADAYFRFVDD
ARRLGADIPVVPGIMPIISSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIKSFGLDVV
TSLCEQLLRGGAPGLHFYTMNQSAATLEILRRLDTD
>A0A5X7K239|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Strasbourg|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTNEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>S8B6K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium oxalicum (strain 114-2 / CGMCC 5302)|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRALVDMALEEAKVLGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCVGVAAYPEGHPADSFQDVQDPARDLPY
LIEKTVAGADFIMTQLTYDIEAYQKFESMLRNHESGVFKTIPIIPGLMPIHSYKILTRVT
KLSHVHLPDPIAKRMEELKHDDDAVKRAGVDIVSEIVGGMQELKSPGPRGFHFYTLNLEK
TVSFILERCDLIPAFTDADDDYALVEADGIVPMGAPARLRRRASSINSQPHNRVIVDKYS
ENVSSHDSVHEALANSAGQPAMLPGRSTTLQISEGLGALGREATWDDFPNGRWGDARSPA
FGEIDGYGPSLHVTSAVARRIWGHPVERSDISTLFRRHVSGELYMVPWSEGGADEGAGLN
AETELIRPELLKLIDGRGWWTLASQPAVNGVRSDHPIFGWGPQREGFVFQKPFVEFFCST
NDYTKILKPLFEKHGHDKLVWFATNNTGAFESSLPTQSADVDLDNLESNPESVNAVTWGV
FRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTERFLDELKNDTWLVCVVGQ
QFGAGTPQGSKEEEDEVKWMWRVLAGETH
>A0A1K2HW38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia enhydra|TrEMBL
MSVTLLDEARMSRQSPAQRPPLSVSFEFFPPKTDAMEARFWESINRLAPLNPRFVSVTYG
AGGSTRERTLRMVSRIEATTGVPSAAHLTCVGASREEVDAVVEGYRAAGVNRIVALRGDP
PEGVGQPFTPHPEGYRNAADLVAGIRRLGDFDISVAAYPEKHPQSADWQADIDNLKRKID
AGANRAITQMFFSNADYLRLVDRARRAGITAPIVPGIQPIHSFRQIAGFAARCGATIPSW
LAERFEGLEEDPETHALVAAAVAAEQVLELVDAGVTEFHFYTLNRANLVMALARLLGIRP
EAQATA
>A0A3A1NHE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda lutimaris|TrEMBL
MKITEHIKKAKGETLFSFEIVPPVKGKSIQELYNNIDPLMEFKPPFIDVTTSREEYVYKE
KDGLLDKKLTRTRPGTLGICASLKHKYDVDTVPHVICGGFTKEETEYLLVDCQYLEIENV
MALRGDARKEEKYFTPTKGGHQYATELVEQIQNINEGNYLHDTIESSDLSSFCIGVAGYP
EKHMEAPSLQSDLKRLKQKVDLGADYVVTQMFFDNQKFFEFVEAAREMGINVPIIPGIKP
IAVKRHLHLLPQVFRVDLPQDLIDAVEACKTNKEVRQVGVKWAIQQSKELRDAGVPVLHY
YSMGKSDNVKAIAKELF
>A0A2G1DH38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malaciobacter molluscorum LMG 25693|TrEMBL
MFKNFIQKLQEDKYLTLETTPQHEPTMHNIIERIKKFDLQHRVDGFSTTDNPLAKLKYNA
LFASMKLQQEFNKPVIATMSMRDRNKIALQSDLLGANEFDVRTILALTGDPAKMSDQPHS
KGVFESNSSMLLKIIKSFNYGMDIAGHPFKIEPKQIYPFAVTNAYARSFSSLQKKMHNKI
QNGAIGIITQPIFEIDNAKKLLEIFNEAKEDVIGNKKKAQLIFGIFPITKLRTALFLSAQ
VPGIHVPQEWIDKLELANQISSEEEYKVGMQLSKDLFTSIKKLHPKIHLMTANKFDLADE
ILS
>A0A2W5DLZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseateles depolymerans|TrEMBL
MSTPVSFEFFPPNTPVGVEKLKTVVQELGALAPQYFSVTYGAGGSTRDKTLFAVMDIAGA
GFEAAPHLSCVGSTRENIAEILATYRARNIRRVVALRGDLPSGTATAGEFRYASELVSFI
RETQGADWHIEVAAYPEVHPQQRYAAQDLRHFADKMAAGADGAITQFFFNADAYFHFVDE
ARKLGVTQPIVPGIMPFHNYGRIAQFAQRDGIDIPRWVQMKMEGFMDDTAAIRAFGLDVI
TRLCERLIVGGAPGLHFYTLNQSPLVLELCKRLGLNARV
>A0A3D5IG93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp|TrEMBL
MRSETARQNGEIRGDIRLSFEFFPPKNPEMENQLWETVAELKKWDPDFVSVTYGAGGSTK
APTLDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIGT
DYRPHPQGYENAAALVKGLRDISDFEVSVSAYPEKHPESASDAVDIDMLKRKADNGATRA
LTQFFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPSFLDERFA
GYDDDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A2S8S9Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Defluviimonas denitrificans|TrEMBL
MATPRISFEFFPPSSLDASFRLWDTVQTLQPLKPDYVSVTYGAGGTTRELTHEAVTTIGK
NYGLRVAAHLTCVDASRAETLEIAEAYAEAGVTDIVALRGDAPKGADRFVPHPDGFANSV
ELVEALAATGKFNIAVGAYPEPHPEAAHQQADVDWLKRKIDAGASRAITQFFFEAETFLR
FRDACAAAGIDAPIVPGILPIISWDGARRFAERCNAYVPPRLEEAFATAIRDGREDLLAL
TQCTVLCERLIQEGVEDLHFYTLNRPTMTRDVCFALGIVPEVSLQNVA
>A0A2H0LKB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG11_big_fil_rev_8_21_14_0_20_63_9|TrEMBL
MTPPALQRFETKLGKKFVVTMEVNPPKGTDLSEIVTAVERVRPLVDAINVTDGSGAMMRA
CSLAVAKVVLDAGVDPILQMTCRDRNRLALQADLLGAAILGIQNVLLLTGDDPKAGDHPD
AKPVFDINSAALMQVTRGLTQGVDMAGKTLSGVPHFCIGAAADPGAKDLEVETQKFKAKI
DGGAAFFQTQAVFDAEPLRRFMERVRPLGKPVLAGILLVKSAKMARYMNEHVWGIHVPEP
LIARFEQAQDKRAECVAATAELIRAVRDVADGIHLYALGWEDLIPDILKEADVVRA
>A0A1A7R7D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter gandensis|TrEMBL
MSLFSEHLTRGQFCISFEYLTTAKPQHVVNHFAGFPAFMTLADRVQTDTDPTPLEVANDY
PQQVEKILHFSGKGRDISDFEVFLDEAQEQSIENLLLLTGDKLKQHNDGVHNPALRSRYL
ESVNQVMAAKQQGGFYLGVAFNPFKYAQAERDAQYFKLEKKIKAGADYVITQLGFDTQVL
ADYQQYMQQHFAQIPVLACIMPLTFARARFMVKQKVAGIVLTPYMLSFLQQEQLADAQQA
EKNVYARCALQILMCQKMGYAGVHLSACHKAQEQNKLALALAEYAKLSLQECQNLWTTLW
QSNSVEDFQPISAHDHAAPLEQVLKYKSMHLMHEVFFSSKMAKGVGGLIFAAKLWNKPKA
DDALLKTEFISKHGIVGCESCGQCRLGETLYICPETCPKGLANGPCGGTTLDRCEFEDRE
CIHSVKARLAQSVGQTEVLKQSLIPTVAIEARQTSSWKNWFYPQKSELS
>A0A318EVR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnotalea glycerini|TrEMBL
MKIREYIKDKPLIFDGAMGTYYSEQQEGKCELANINNRERIIEIHRKYIAAGCVAIKTNT
FAANTISLEKDLELVKRVIAAGAQNAIQATDGREIFIFGDMGPIPYAGEGASPLCEYKEI
VDVFIENGIKNFLFETLGSDEYLSELSQYIKNKNKDSFIITQFAVTPDGFTRIGLSGKNI
VKRVEEIEEIDAIGFNCVSGAHHLYEYIKQFKTVQKYISIMPNAGYPTVRNNRTIFENSS
DYFAETLYKMAQLGVNILGGCCGTTPEYMRKTVDLMTGFKKPRRIEYKKQEIEENAETDK
ENGLIKKIGLGQKIIAVELDPPSKAEIAGFMEGAKRLKYNGVDAITIADCPLARARVDSS
LLACKLKRELDITPIPHMTCRDRNINATKALLLGLSIEGVENVLVVTGDPVPSPMRDEIK
TIFNFNSAILAKHISELNETVFDAPFGISGALNVNSRNFDSQLKHAQKKIDNGVSMLFTQ
PILTEEAFENLKRAREVLSAKLFGGIIPIVSHRNACFMNNEISGIKVSQEIINRYEGKTR
EESSELAVQISTDIAEKISNYVDGYYIITPFNRVEIVEKIVKKIKSL
>A0A2A2HWA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina spelaei|TrEMBL
MLFNFREKLNSSKFLVTAEVSPPKGTRFSVPLEDARQLKGIADAINVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICVMTGDFPSCGDHPGSKP
VYDLDSVHLLQLVRKLDSGINFAGNRLDGGTSFCAGAVSGIDPDKPLQLIKLEKKVRSGA
DFIQTQAVYDVGMFEEFMEAISYLEVPVIAGLIPLKSLGMAEFMNKNISGVNVPEEIMFR
IKDSPDPVEEGLSIASETIKELMKLSRGVHIMPVGSHNNTSRLLSMAGLSGK
>J8E5C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus HuA4-10|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEVLKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPNFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRVHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQKMDGHETKETAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7R7GGT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. KC14|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEKTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASREELKQIAQDYWDSGIRRIVALRGDLP
PGVDKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIS
QFFFDTSVFLRFRDRAAAAGVDLDLVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DEDDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRGNG
>A0A7G1G4W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepiditoga spiralis|TrEMBL
MYIKDIFKEKKPVISFEIFPPKKESNIKTIYKTIDELAQLNPDYISVTYGASGSIKNNKT
VEISSFIKREYKIEPLSHLTCINSSKKEIDEILNQLIENNISNVLALRGDIPNDKNIKKE
FNYAEDLIRYISKKKKFSIGAACYPEGHIEARNKSLDLYYLNKKVNAGTDFLITQLFFDN
KYFYDFREKLKNRNINIPLQAGIMPVVNKKQVEKIVSMCGVNIPEKFIKIMNKYENNKEA
LIDAGVTYACDQIIDLLTTGVDGIHLYVMNKSKIAKEIVKRITSILKINIKMEE
>A0A7W5ESW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas stenophila|TrEMBL
MSAHEHPLGISFEFFPPNTDAGRDKLMRTRDALAPRQPRFFSVTYGAGGSTQHRTLNTVQ
AVRESGITTAPHLSCIGSEKAVLRDLLAQYREQGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSLDRDVENFARKMKAGANLAITQYFFTADAYF
HFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAF
GEEVISRLCQRLLDGGAPGLHFYTLNQAEPTLKVLDNISA
>A0A367B9F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. TF02-8|TrEMBL
MNRALTVRDPSTRASLRQTFQTLGYEVIPFKKTQEQVLQHVPTDVRLTVTASPAKGQDAT
IDLTVALAGHGYTVAPHLSAQQVRDRSHLADIVARCREAGVTDVFVIGGDPTETPTEFKD
AHALLVALHELDHGFTDIGIGGHPEGHPSVGEDVLFQALEAKAALAHHITTQIVFDPAVI
LRWARELKRRGIDLPVHVGVPGAVSRQKLLRVSGGLGIGESAKFLKKQQTLLWRFFVPGG
YDPSKIIRGLAPHLGKPDNGLAGFHVFTFNDLEPTEEWRTRTLRNLA
>S5V4P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces collinus (strain DSM 40733 / Tue 365)|TrEMBL
MNPALSAPPAAGTALLDDFSLEMTGKDVPKLEEARDTIPRGTRINVTFLAGEDPGTRLAA
ARAVKRLGFVPVPHISARRLPSRRHLEEFLAGLAADGTADNVFVVGGDPARPEGPYEDAL
SVIRSGLLQRHGVRHVGISGYPEGHPAIADHSLWSALSDKTAALGADRLAGDVITQFGFD
AEAVLRWVAAVRDRGVRLPVRVGVPGPAGARRLVSYATRFGVGTSASIVRKYGFSLTNLV
GTAGPDRFLHTLARDYDPARHGELKVHFYTFGGLRTTSEWIARFRHGDRH
>A0A413FYY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF02-46-1|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFNTPSVAHLTCVGRSHADIVAKIDEYRSAGVENILALRGDLPTGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A4R6VQI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora succinea|TrEMBL
MDDDDAVRRLLADFSIEVTPRETAALDEAATVLAPGTRVYVTDLAGVDLQRALDAAARIR
ERGLRPVVHLAVRAIPDLAALDRALGRLVDAGVEDLLLIAGSREPAGELENTSQVLESEV
FARRAFASIGVAGHPEGNPGVDEGAVDLALASKDKLAREDGLPLYVVTQFGFAADPVLGW
ERRMRDAGITLPVRVGLPGLTSPARLVKFGLSCGVGPSLAVLRKQTGSVLKLATATYRPT
DTVRGLARAVAADPESLIAAVHFFPFGAVVPTARWATTGQKDGLGAERT
>A0A379J0Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mendocina|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGDHFHIEVAAYPEMHPQARNFESDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSDSIRAFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLDLKR
>A0A501S1P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea vagans|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWTSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMNAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAAA
>A0A1S1SXI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. LCM 4579|TrEMBL
MSPDINPHDPGAPLEPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLKTVRTMRDNSKFLSGRKLTTPPHVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFRAYMNKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHDSGVLKGRRPWQREAAPTDRLVAERLDHIREGIEENQQQMAEAAAH
HPH
>A0A6P0TM53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanothece sp. SIO2G6|TrEMBL
RNLNTGLDANDQPLPDDSTDLFAGAAVDPQSKSWSGLQRRFEQKVEAGAQFFQSQLISDF
GKLEKFMDGIAAGSNRPILAGIFLLKSAKNARFINRCVPGVDIPETLIHRLETAEKPLQE
GMKIAAEQVQIARQLCQGVHMMAVRREDLIPEILDLAGVAPVQSEDYAVDSDPKAEVDSD
SKVSEPKPSDHKASAPKTDDQGVSASSKTSSPLVGLSH
>A0A6P1HUM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. WAY2|TrEMBL
MTRTPSIVDRIRSCRDGRVPFSVEFSPPRDEAAEARLWRAVREFERLGPAFVSMTYGAGG
STRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRGISNILVLRGDPPGD
PLGEWKKHPEGVEYAEELVRLVRELGDFHVGVASFPEGHYRAPDLDHDTRYLVAKLRAGA
EYSITQMFFDIDDYLRLRDRVAAFDAEQGEKPIIPEIMPITSLRSVQRVMELSGSRLPVA
LERRLSRAAGDGPEENRAAVREIGIDVATEMAERLIAEGAPGLHFITLNFARATSEVLAR
LGDKVGSRTDPRPVTPARVS
>A0A2W4I800|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Melainabacteria bacterium|TrEMBL
MPKKATRRHMTHPFLKELAKRPLLADGGIGTLLYARGASPEASFEHLNLTKQDEIQKVHI
DYINAGADVIETNSFSANRYRLASFGLEEETHKINLWAAKVARNAREVGGQPVFVAGSVG
PTGKLMAPIGDVTANDLKDAFTEQMEALLAGGVDLFMIETMSSLEETAIAVRAARAVSKL
PVVAQMSFSPDGHTLLGVTPEDVVKLFVELGEDAPDVIGINCGAGPGPVFDSLLRMSHAL
KERGVDPLKLNYSCLPNAGQPSLSGGRYQFMSGPDYCASYVEPYVRAGARLIGGCCGTTP
HHIKAMRAELDKYILSQKTASAATAQDLPAMKPEALISLSGKTRPAEVKKEAPKAGNELP
ALAARLTAAKANPKNGDFYVSVELDPPKGAIARKILQAAETLKDAGADAINVGDSPMARV
RMSSLATCQLISTKVGIETIIHFTTRDRNLMGIQADLLGCQALGIHNVIALTGDPPALGN
YVHATAVYDVDSVGLIKIISQLNQGLDIAGNSIGTPTSLSIACALNPTHENRAQELDRFG
KKIEAGAHFAMTQPLYQLSDLTNFLDEFGECKIPILVGIMPLHSFKHAEYLHNEVPGITI
PDKVRKAMEKAGDQGAAVGLELAEELLEQLRPLCQGTYVVPSFGRYDDMCQFVKRIKSKS
QAKAGAKS
>G2HSS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp. L|TrEMBL
MFETLIQKLQEDRFLTLETTPQHEPSMHNIIERIKKFKLQDRVDGFSCTDNPLAKLKYNA
LFASLKLQTEFNKPVIATMSMRDRNKIALQSDLMGANDFDVRAILALTGDPAKMSDQPHA
KGVFEANSLMLLKIIKSFNYGMDMSGHPFKIEPKQIFPFAVTNSYAKNFSTLEKKMNLKI
QNGAVGIISQPVFDIENAKKLLESFNIAKEGVEGDKKKAQLIFGVFPVTKLRTALFLSAQ
VPGIHVPQFWIDALETAHNISEEEEYKVGMQLSQDLFRDLNKLHPKIHLMTANRFDVANE
IIS
>A0A2T7Q5Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrimonas sp. NS-102|TrEMBL
MKVTDHIKQAKKTLVSFEILPPLKGKTINSIYDHLDPLMEFKPSFINVTYHRAEHIFKKK
ADGNFEKVEIRKRPGTVGICAAIMNHYKVDAVPHLICGGFTIRETEDALIDLYFLGIDNV
LLLRGDAAKNEAFFEPEPEGHRYAIDLLKQTANLNNGIYLEDNIRNGFRTNFCMGVAGYP
EKHFEAPNLATDLSYLKAKVDAGAEYIVTQMFFDNKKFFDFVDNCRANSINVPIIPGLKP
ISSKKQLSVIPRTFNVDIPTDLSIEILKCKTDADVELVGTEWLKQQSVELKKSGVPILHY
YTLGKPKMVENVVKEIV
>A0A2H0CCT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG22_combo_CG10-13_8_21_14_all_43_16|TrEMBL
MALCDKIKSGKFIITSEIAPPKGIDVEEILKDAELVKGRVDAINVTDLQSSVMRTGSLAI
CKLLIERGLEPVFQITCRDRNRLALQSDLLSAAVFGIENVLALTGDHPALGDHPGAKPVF
DLDSMQLLEAIRDLQAGKDMAGKELKGSPKFCVGAVVNPGADPIEPEIMKMEKKIQSGAQ
FFQTQAIYEMHLFEKFLKASEHLHTTIIAGIVLLKSAGMARYMNKNVAGVFVPDNLIEEI
DKAKDKSAKSIEIAARLIKELKPMCQGVHVMPIGWDKKVPLVLDAAGL
>H0GUP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae x Saccharomyces kudriavzevii (strain VIN7)|TrEMBL
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRD
ADSWTPVEGGFLYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDAKLDLEYLKQKID
AGGDFIITQMFYDVDNFISWCSEVRAAGMAVPIIPGIMPITTYAAFLRRAQWGQISIPQA
FLSQLEPIKDDDELVRDIGTNLIVQMCQKLLNSGYISHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANRCLELWSTPASINDIAFLVINYLNGNLKCLPWSDVPIN
DEINPIKAHLTELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDILKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKNTPS
>A0A1E3K7K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus amylolentus CBS 6273|TrEMBL
MKITDKLQKAEKEGRPFWSFEYFPPRTAQGLQNLFDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVEICQSTIGIETCMHLCCTEMPKEKVEWALKQAKQNGCQNILALRGDPVAGTST
WEPTPGGFMNAIDLVKYIHKNYPGDFCVAVAGFPQGHPESPLTPEGKEQEMKWLKEKVDA
GADFIFTQMFYDTDIFFDWVKRVRAAGITVPIIPGIMPIQNWEKFDKWVQRENIIVPQHF
YDALNPVKGDDEKVRQVGTKLVAEMCRKILDNKEAGIKGLHVYTLNLEKGARMLLQELGF
EGRREQIAPLPWRPSLTPNRRDETIRPIFWANRTRSYISRTEDWDEFPNGRWGDSRSPAY
GDLDGYPVSIGISATEAYNLWGNPTTTTEIYNLFAHFCRGELTKLPWSTQPPASETSVIT
DQLTKMNELGYLTINSQPAVDGVASDDKVHGWGPSGGYVYQKAYLEFFVSPELLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIIQPTIVEAVSFVAWKDEAFE
LGLQWANLYPAGSPSRELITKVMNDSYLVNIVANDFRDGLSIFEPFLLDQTPVGKVVEGV
KGVVEGVVEGVKSVVAE
>A0A4V1BED4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides euryhalodurans|TrEMBL
MPPKDEAGEEQLWRAISELEPYRPTFVSVTYGAGGSSRDTTVRVTGRIARETSMVPMGHL
TCVGHTREELTDILASYAAAGVHNVLALRGDPREGPRAEWTPTAGGLTHADELVSLARGI
GGFTVGVAAFPGGHPGAESIERDVEVLLQKQRAGAEFAITDMVFRVGDYVDLVERARAIG
ADLPILPGIMPILNLGQVTRMAELSGREIPAEVRARVEQHASDPAALRAEGIRMAAELCE
QLLDAGAPGLHFYTLNRSRATREIFAALRITV
>A0A3D4UCH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxellaceae bacterium|TrEMBL
MSKHFSFEFFPPKTDAGAVKLRDVTKTLATLQPEYFSVTYGAGGSTRDRSLGTVLEIQHN
SGRPAAPHLSCIGDSREELAELLATYKANGIRHIVALRGDLPSGMGGAHGELAYAADLVK
FIRETTGDHFHIEVAAYPECHPQAANLSTDITNFVNKVKQGASSAITQYFFNADSYFHFV
DEVRKQGVDIPVIPGIMPITNFANLVRFSDACGAEIPRWIRKQMASYGDDTVSTQKFGED
VVTQLCEQLLEGGAPGLHFYTMNQTEPTMALWRRLGLPGA
>A0A519Z720|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp|TrEMBL
MKVTEHLRRAEGKTLFSFEVLPPRKGENIHSLFSNIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRKRPGTVGICAAIKNRFDVDTVPHLICGGFAKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFQPHPDGHTYACDLIGQVADLNHGRYHDHDEQYQPLGSEPVLCTDF
CIGTAGYPEKHFEAPNHGSDIRFLKQKIDRGADYIVTQMFFDNEEFFKFEKRCREAGITA
PIIPGLKPLTTKNQLIALPRAFFLSIPEALAEAIHHAKDNAAAREVGIEWCLNQSRELMA
HGVPCLHYYSMGKSESIRRVAASLF
>A0A412C2V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AF27-33|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEIAKIIY
>A0A1F9MIX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYD12_FULL_53_23|TrEMBL
MLVKDILEKNRISFSFEFFPPKDESGWEYLFATISDLMPLKPAYVSVTYGAGGSTRDRTH
KLLVRIQQETSLTVVSHLTCVGSNREETGAILRNYAASGVKNILALRGDPPKGQTDFVQP
PDGFAYAADLVAFIKNNFPQMGVGVAGFPEGHPATPNRLLEMDYLKAKVDAGADYIVTQL
FFDNRDFYDFRDRCALAGITVPIIAGLMPITTKSGMVRMAELAAGARIPASLLRGLDRAR
SDEQVEKVGVHWTTEQVRDLIDNEVRGIHFYTLNHSRQALDIYQTLGVEDSIQLGA
>A0A1B4NNG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia latens|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAQHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSDMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAASATRTICERLSM
>A0A505I4Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus niger|TrEMBL
MGSAVRHGAFSGGSIGGRKSCSSPPPSFTPSFLAFHSLSSVRHRVAVSAAAETGLIMEKI
TDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGSTAARS
LELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMH
GEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDGQDPARDLPYLIEKT
QAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTKLSHV
KIPPHVLSKLEEVKHDDDAVKRIGVDIITDLVHGIRDLVSPGLRGFHFYTLNLEKTVSFI
LERCELIPPYTEIDDSDALADGGNLSALDSSSYIAPNGAPIRTLASRRSSVSSIPHNRVI
VDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWSEGGA
EEDSNGLNAETAIIQPELLTLIDKKGWWTLASQPAINGVRSDDPVFGWGPPGEGFVFQKP
FVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNTDDPDPIDINPANV
NAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDDTKNDVW
LVCVVGQEFGAGTEPGSEEEEDEKKWMWRELANSQ
>A0A519ZJ32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp|TrEMBL
HEAAGITVPIIPGLKPLTTKNQLIGLPRSFFLSIPEALSEAIHQAKDNAAAREVGIEWCL
NQSRELMAHGVPCLHYYSMGKSESIRRVASGLF
>A0A848IIA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia polaris|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFANKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTDLCQRLIDAKVPGLHFYTLNGAAATKAICERLGA
>A0A256IEU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halorubrum sp. Ea1|TrEMBL
MSAGTQAIKRSDGVGALLTDARFELMPFESFEDEIRHLPDDATIAVTTSPQLGIDTTVER
TEQAAALGYDVSPHIAARYVEDRDHLDEIAERLTDAGVTDIFVPGGDREEPAGEFESAHD
LLVALDELGHSFDEVGITGYPEGHDFLDAEALSDAMAKKSPYATYLVTQLCYDPDAVLEW
IDDIRDDGVDLPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVRQLVGSRG
VYKPDDLIDGLAPYADDDHYKIRGIHIYTFNQTPDTESWRTERLGR
>A0A8H5MM85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium mexicanum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLASDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>F7AQ98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monodelphis domestica|TrEMBL
MAEAAAARDWRQPESCRNPAMVNEARGSCSEGSSSGSEGSKDSSRCPTPILDAERHERLR
EKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKE
TSSMIIANTAVDYCGLETVLHMTCSQQNRDEITSHLHKAKRLGLKNILALRGDPIGDEWE
EEENCFSHAVDLVKHIRSEFGDYFDICVAGYPKGHPEATSFEEDVQYLKEKVSAGADFII
TQLFFQADTFFNFVKACTAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEP
IKDNDAAIRNYGIELAVTMCKELLASGLVPGLHFYTLNREVATMEVLKRLGMWNEDPRRP
LPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQAWDEFPNGRWGNSSSPAFGELKDYYLF
CLKSKTPRTELLKMWGEELTSEESVFEVFTYYLSGEPNQNGYKVTCLPWNDEPLAAETSL
MKEELLKVNQRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSETVEALL
QVLKKYELRVNYHIVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDE
AFALWIEQWGKLYEEESPSRMIIQYIHDNYHLVNLVDNEFPLDNCLWQVLEDTFELLSSP
VQ
>F7AQ98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gray short-tailed opossum|TrEMBL
MAEAAAARDWRQPESCRNPAMVNEARGSCSEGSSSGSEGSKDSSRCPTPILDAERHERLR
EKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKE
TSSMIIANTAVDYCGLETVLHMTCSQQNRDEITSHLHKAKRLGLKNILALRGDPIGDEWE
EEENCFSHAVDLVKHIRSEFGDYFDICVAGYPKGHPEATSFEEDVQYLKEKVSAGADFII
TQLFFQADTFFNFVKACTAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEP
IKDNDAAIRNYGIELAVTMCKELLASGLVPGLHFYTLNREVATMEVLKRLGMWNEDPRRP
LPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQAWDEFPNGRWGNSSSPAFGELKDYYLF
CLKSKTPRTELLKMWGEELTSEESVFEVFTYYLSGEPNQNGYKVTCLPWNDEPLAAETSL
MKEELLKVNQRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSETVEALL
QVLKKYELRVNYHIVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDE
AFALWIEQWGKLYEEESPSRMIIQYIHDNYHLVNLVDNEFPLDNCLWQVLEDTFELLSSP
VQ
>A3U1X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudooceanicola batsensis (strain ATCC BAA-863 / DSM 15984 / KCTC 12145 / HTCC2597)|TrEMBL
MTAPAVSFEFFPPQSLEASFRLWDTVQVLSPLNPRFVSVTYGAGGTTRDLTRDAVATLHK
HSGLNVAAHLTCVKATRDETLAIAEGFADAGVKEIVALRGDPPKDEGRFSVHPGGFANSV
ELIEALAGTGKFTIRVGAYPEKHPEAATDAADVEYLKRKFDAGADEAITQFFFDKAHFLR
FRDACAKAGIDKPVVPGIMPIENWKGIRRFALNTGTSVPAWLDDAFDKAARDGRQDLLAT
ALCTEMCTELMAEGVDKFHFYTLNRPELTRDVCHAIGVTPSVRLENVA
>A0A4P8C8Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O145:NM|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPLGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A660RW10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteria bacterium|TrEMBL
MEEKSHLQKVLENGYFAVTAEISPPRSADSEAVREKAKLLKGYVDAVNITDCQTASVKMS
SLSSAVIVMQEGLEPVMQMTCRDRNRIGIQSDLLGASALGIKNLLCLTGDHPKFGNHPQA
KPVFDLDSIQLLSLVKGLCEGKFLNGEEIKGKKPWFFRGAVENPFADPLEFRPIRLAKKI
KAGAQFIQTQIVYNIERFKKFMEMCEEQELLDKVYILAGVTPPKSLGMLKYIKYNVPGLD
VPNELIKRMKSAKDKKEEGINIAVEVIEKVKKISGVRGVHIMAIGWESIVPEIVKRAKLY
PRPEIS
>A0A2N7FCX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio splendidus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A165EZ00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calocera cornea HHB12733|TrEMBL
MQNLLDRIERMREFGPEFIDITWNAGGRTSELTSELVRCCQRDLGIETCMHLTCTNMPAE
KVDIALKEAKQWGCRNVLALRGDPPFGQEQWTKTEGGFEHGIDLVKHIREDHGDYFDIAV
AGFPEAQNRPDRDIEMKYLKEKVDAGVNFIFTQMFWDVDLFITWVKAVRAAGITIPIVPG
IMPIQTWNGFQRATSLAKITIPDSLLAKLEPYKNDDEKVREIGTQIVADMCRKILAADIG
IRGLHFYTMNLERGTRMLLEALNFVPHIEVVRPLPWRQALTPTRRGENIRPIFWANRVKS
YIHRTENWDEYPNGRFGDSRSPAYGELDGYGIWIKQTPEEGRKIWGEPKTFDDVCKLFSK
FCNGELKSLPWSDTAPASETTVISTELARLNELGYLTINSQPAVNGAKSTDPVHGWGPRN
GYVYQKAYLEFFVDKKKFEELVLRIERDPMITYYAIDKHGNLRTNNHSDGPNAVTWGVFA
GKEIIQPTIVEAVSFLAWKDEAFELGMQWSRIYEPGSVSRKLLESIMETFYLVNIVHNDF
QDPQAVFAAFGLETKKANGTANGGAH
>A0A1Y6FWJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis terrae subsp. ummariensis|TrEMBL
MTTSLDALAEARRAAASPLFANLEGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLAPRFV
SVTYGAGGSTRERTHATVARIASESAVPPAAHLTCVEASRAEIDEVARAYWDAGVRHIVA
LRGDVPGGGAYRAHPDGFANAVELVAGLKRIAPFDISVAAYPEVHPDADCPQADLDNLKR
KLDAGATRAITQFFFSPEAFLRFRDAAAAAGIDAPIVPGILPVSNVSQTRRMADMCGTAI
PAWMIALFEGLDDLPAARQLVAATVAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHMLG
LRPVAPAKDKAA
>A0A4P8KTW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. RG1|TrEMBL
MTGKDIPGLEEAREVIPAGTKINVTFLGNEDLDMRVAAAKAVKDAGFVPVPHVSARRLAS
AAQLEEFLDRLQQVGATEHVFAVGGDPAEPEGPYPDSLSVIRSGILQKYGVREVSIAGYP
EGHPDIPTDVLWRHLEDKSSALADAGLGQVILTQFAFDTDPVIDWIDGVRERGITSEIRI
GTPGPAGIKRLITFARRFGVGANAMIVKKYGFSLTNLMGTAGPDRFIGDLGALVAQKESR
GPVKIHFYTFGGLRATSDWARDYIAAQS
>A0A1A8M379|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius pienaari|TrEMBL
GYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIHQAVEMCRVLLDSGKVPGLHF
YTLNREVAPTEVLRQLGLWIEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQD
WDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEELKREESVFEVFTCYIT
GQLNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTDAVVGW
GPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAHEMQPNAVT
WGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVN
LVDNDFPLESCLWRVLDDMFELLDAPLETLADGMSGDGSHGNGTLAE
>A0A496QHH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteria bacterium|TrEMBL
MISGSNLEQVLTSGQFTVTGELGPPQNGNFDIVRDKARILKGHVDAVNITDCQTAIVRMS
SLTAGLIALAEGVEPVMQMTCRDRNRIGIQSDILGASALGIKNLLCLTGDHQKFGNHPQA
KGVFDMDSIQLLGMVKAMRDDKKFQCGDEIKSHEPRLLLGAAANPFADPFEYRPIRVAKK
VDAGASFIQTQ
>A0A5P9C3L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. THAF187a|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLTLYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRNETGDHFHIEIAAYPEMHPQARNFESDIANFVRKAKAGANSAITQYFFNADSYFH
FVERVQKLGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVESIQAFG
QQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A2N7JLQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio splendidus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVKLLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A426FZX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYD
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARAIHQAIHSLFKHYS
>A0A1Q5D1X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02414|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPEGLTYAAELVELIKESGDFCVGVAAFPEMHPRSADWDADVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEIMPVTSVKMLERLPKLSNASF
PAELKERILAAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A6A5VWY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bimuria novae-zelandiae CBS 107.79|TrEMBL
MHISKMLAQSKEEGKATFSFEFFPPKTAQGVQNLYDRMDRMHGLGPKFIDVTWGAGGSLS
HLTCEMVKVAQSVYGLETCMHLTCTDMERSKIDDALKTAYDAGCTNILALRGDPPRESEK
WQQVQGGFKYAKDLVKYIREQYGDHFDVGVAGYSEGCDDNDDVDELIDHLKEKVDAGGTF
IVTQMFYDTDIFIDWVHKVRAKGIDVPIIPGIMPISTHAAFLRRAKWSKIKIPGSWTRAL
EPIKNDDSEVREVGKGLVADMCRKLMDAGILHLHFYTMNLAQSSRMVLEELDLLPDVESP
LQKPLPWRPSLGLKRREENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDARSPAFGEFDA
YGIGLKGSNEQNIKLWGKPTSVKDISNIFVKYMSGDLESLPWSESAISKEADTLQQNLID
LNRRGFFTINSQPAVNGAKSTHPVYGWGPAHGYVYQKAYLEILVSPEYIAELITRIERDP
EITYYAVNKDGDLKTNSPEGPNAVTWGVFPGKEIVQPTIVEAVSFLAWKDEFYRLGQQWA
NCHPSVSPSRYVIEDVMDTWYLINIVHNNFQENNGIFPLFDGLEVAEMEKELHSTGLSNG
ETTNGDSEANGNGRPTPTTRKSTLNDLVEAAKSAASTVTNGITA
>A0A6Q2X454|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Esox lucius|TrEMBL
MVNQVQTVDDTWRRCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESVLHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPIGTDWEEEEGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAQSYDEDLKHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKENDAAIR
NYGIEHAVGMCRMLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEKSVYEVFTSYIMAEPNQAGHKVMCLPWNDEPLAPETNLLKDELAKVN
RRGVLTINSQPSINGKPSSDSIVGWGPPGGYVFQKAYLEFFTSSENVTALLQVLKKYEPR
VNYHIVNVQGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDSFYQYANTPTA
LM
>A0A0M0LAI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Viridibacillus arvi|TrEMBL
MGLLEKLQTQVLTADGAMGTLLYSYGIDYCYEELNITKPEVIENIHQQYIKAGADIIQTN
TYTANAIKLERYGLESSVKEFNESAIAIAKRAAAPGGQFVLGTIGGIRGIRKSEATLEAI
IAALDEQAGYLLAGNPDGLLLETYYDFEELSSVVKHLRKLTDLPIISQVSMHEPGILQNG
LLLNDALHQLEALGADIVGVNCRLGPHHTIQAFEDVELPSKAFLSAYPNASLLDVEDGKI
VYESEADYFGRAGVLLRDQGVRLIGGCCGTTPKHIEAVKKRIADLPPIENKIVKKKKVIE
IKEATPDHHEPLHEKAKRERTIIVELDTPRHLDTTSFIEGAQILNSTGVDAVTMADNSLA
SPRISNMAMGSILKTQNNIRSLAHITCRDRNLIGLQSHLMGLDALGINEILAVTGDPTKV
GDFPGATSVYDVSSLELLQLIKQLNEGISFSGKPLRKKANFSIAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVYTKEKIIEIYEATKHLETPIFIGIMPLTGIRNSEFLHHEVPGI
KLSDEVLERMRATGDDKNLATAEGIAIAKELIDTAAELFNGIYIITPFTRYDMSVELIHY
IQELDQQKVGDHNYVKTTN
>A0A8J3T4V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planobispora takensis|TrEMBL
MPTVRELLAAGGRSFSFEFFPPKTDEGERQLWRAIRELEALRPTFVSVTYGAGGGTRDRT
VEIVERLAHETTLTPVAHFTAVNHSIRELRHLVGRFAGAGVRNILAVRGDPPGDPMGEWV
RHPEGVLYAEELVRLIRQSGDFCVGVAAFPYKHPRSASVESDTEYFVRKCRAGADYAITQ
MFFRAEDYLRLRDRVAAKGCDTPIIPGIMPVTQMSTIARSEQLSGAPFPPEVAARFEAVA
DDPVAVRRLGVEHAAELCQTLLDEGAPGIHFITFNRSSATREVFQALDAARETAPVTA
>A0A8J3WQZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planobispora takensis|TrEMBL
MRFDELVRSGGPVVTAEFPAVDTDMAALVRHADRLRGWADAVNVTDNTAAHAHASNVAVA
VALRGLGLEPIMQVACRDKNRLALQADIVGAALHDVRAVCCLTGDDVTAGDEPQARRVFD
LDGPQLIRVACALAEGRYLSGRVIDPAPELLVGAVENPGAPPYSHRVDRAAEKIRAGARF
LQLQICYHPDRLAAFMAGAARAGLTSRAAFLATICLVRGAGGLRFMNEKVPGISVPAETV
DRVERAADPSRAAYELALAQARHALGLPGVRGLHLVDFRGGDAVARLLSDLRISRRLTA
>A0A8E2LIQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioclava marina|TrEMBL
MTTPKVSFEFFPPQTLDASFRLWETAQVLAPLQPEFVSVTYGAGGTTRKLTHEAVGTIHK
NYGLNVAAHLTCVEATRAETMEIVNSYAEVGVTEIVALRGDPPKGAKGFVPHPEGFASSV
ELIEALAEDGRFTIRAGAYPEPHPEAADPLADVRWLKRKVEAGATSAITQFFFEAETFFR
FRDACEREGINAKIIPGILPIQSWKGAKNFAQRCGTSIPAWVEEAFEAAIRDDREQLLAT
ALCTELCDKLIEGGVEDLHFYTLNRPGLTRDVCHALGVTPEAVLENVA
>Q6FBE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)|TrEMBL
MMSSLSECLDQKQFCILVEYLCSVKSPLAVRKTLANFPAMMTLADRVHADNDPAPLDLAT
KYPDTVDKLIHFSGKARDIKDLERFLNDLENTTIRNLLLVTGDKLKSHDFGYEVAAQRTR
YLESVSAIMAAKQRQIFKIGVAFNPFKYTEAESDAQYLKLHKKIKAGADFLITQLGFDVE
CLQQTQVFLQKNYPNFSALACVMPLTLKRAQFMVKNRVAGIVISDHVLQTLEKEYQSDPI
QAEINVYARCALQILICKHFGYAGVHLSACHKEDEQKKLEQALKVFENFSLNECQQAWKD
LWQADAQGDFKPNVKISSKPVTQTQILKYKKMHTMHRMFFESKMARTIGHFVFKPSFWNR
SNAQNILLKIEHSSKHRLVGCESCGECRLGDTLYICPETCPKGLANGPCGGTSLDRCEFE
DRECIHSVKARLAKKIHQTEILKTKLIPAISITTRHTSSWKSWFTDTK
>A0A8B7YDE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acanthaster planci|TrEMBL
MNQSHPPTGTMSSAVNGSARPKKRHSDSSSSGSESSTTPLSVSRSPSPSNTPLIDRIAQR
IACKDKWFSLEFFPPRTANGAVNLLARLERMHVGGPLFCDITWHPAGNPGGETETSSITI
ATSAINYCGIETMLHMTCVNQTRIDITKYLNRAKDCGIRNILALRGDVPGDLEWQKSDSE
DTFNYALDLVRYIKKMFGDHFSICVAGYPGGHPEAESYEEDLKYLKRKVDAGADFIITQL
FFKAKEFLQFYKDCRAIGITVPIIPGVMPIQGYSSLRNLVKLSKLDIPEDILKVIEPIKD
NDAAIRNYGIHQAVTMCKEMFDSGDVHGLHIYTLNREVATIEILKRLGLWNEDPIRPRPL
PWKTTANHMRTKEDVRPIFWAARPKSYIHRTKDWDDFPNGRWGDSSSPAFGDLKDYHLFY
LKSKSSKEELQQMWGEELACEEDVFEVFKCYLDGEPNRYGHKVKRMPWNDDELASETSRL
RDRLISINKRGILTINSQPAVNGAPSTDPVVGWGAPNGYVYQKAYLEFFTSRENAAALLD
VLRDYPSVTYHVVNHNGKEDITNTDRQQPIAVTWGAFPGAEIIQPTVVDPISFMVWKDEA
FGLWKHQWGHIYSEGSPSRQIINHIHDTFYLVNLVNNDYVQDDYRLFEVLEKMLARKEER
RREEIEGPDLDEEICSKKLKIDSQSAASTEGIPSSVVIP
>A0A2N2KMK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-12|TrEMBL
MSDQQPLQEYLREHLVIGDGAMASWLFQKGVPIGLCCAELNLSRPDLIVDTHREYYAAGA
RLLETNTFGANRDALSRHGLEDRVYRINWKAAGLARDAAGRDAWVMGSMTAISSGRVRHE
ILPGHREMFIEQAEALLAGGVDGLILETFLDLAELLLALKAVRPLTTLPIIAQLACMEVG
KTRDGFSVSDSFRRLSDSGADILGLNCRLGPGEILRTIEQASVPEGMVLSVFPNAGRPGL
MEGEFGYTSSPAYFAERALRFREQGVRIIGGCCGTTPEHIRAVADALTGLLPINRLNPEP
PPEPMPRTAVFVSSISDTLLERVKQRPTVLVEFDPPKDLDIEQYMIGAASLQDAGADVIT
MADNSLAQTRMSNLALGAIVKMRLGIDPLVHIACRDRNLIGQQSHLMGLHALGIHQILVI
TGDPARFGDLPGASSVFDVSSFDLIRMVKQLNNGISFSGQTLRERGRFIVGAAFNPHVTN
LASAFNRLERKIEAGADFILTQPVYDRATMEMIAEGTRHLPAPIFIGIMPITSARNAEFL
NNEVPGIRLTKEAMMRMGKYPAAGPDARKEGLDIARELVDAARKYFQGFYLMTPFAYHDM
TAELTRYVKNKRPPLK
>I2JP22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium BDW918|TrEMBL
MANRYSFEFFPPKTEVGRAKLKDTRSQLAALNPEFFSVTYGAGGSTRDNTRDIVLETKKA
GLSVAPHLSFGGDEESEILTLLNDYKAAGIDRIVALRGDIPSGMGATRQVYAKELVEFIR
KHTGDHFQLEVAAYPETHPDAKSHQADIQFLKAKLDAGANSAITQYFFNADAYFYFLEDC
EKAGIDKPIYPGIMPITNFSNLARFSRNCGAEIPRWLAQKLEGYGDDQQSIIEFGAEFVS
ELCHILMEGGAPGIHFYSMNQVEPIKSIAEAVMSSHPAG
>A0A3E4UEG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi|TrEMBL
MKTTDIFAKKPVLSFEVFPPKRTNPVETIYETLDSLRKLNPDFISVTYGAGGSENCKATT
EIASRIKNEYGIESVAHLPCIGLKRDDVISLLGGFKRAGIDNILALRGDIPEGGRPDGDF
EHASDLISFIKEHDEFREFNVLAACYPEGHTESENILTDIRSLKTKVDAGADHLITQLFF
DNDCFYRFLERASLAGIHVPVEAGIMPVTNKKQIERMVSLCGVSLPSKFTAMMERYEHNP
EAMRDAGIAYAVDQIVDLIARGVDGIHLYTMNNPYVAAKIHEAVYRLLAA
>A0A2E6E8F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia sp|TrEMBL
MGNLQDKMAAGFVVTSELVPPKGTDIQALLDTAGMLQGYVDGFNITDSHSARMRLAPVAA
AHMLIDHGVEPILQMVTRDRNRIAIQSDMLGADVLGITNLVCMGGDPPHIGDHPDAKPVY
DLSSDEVISVANALNNGSDYAGNKLNQSTNLHIGAVVNPGATDLDTEIAKMEKKANAGAR
FFQTQAVYDVEAFQNFMSAIAHLDVTVIAGIMPIKSVKMAEYANEKIPGICIPQSMIQEI
ADADDVAECSIRIASDIISALQSVCGGVHIMALGAEDRIPRILDRVRA
>A0A2G5P6X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium brumae|TrEMBL
MTSEHSERPSVSVVDRIAEIAKGRTPFSVEFFPPRDEAGEAQLWRAARAFEPMGPAFVSV
TYGAGGTTRDRTARIVGELASTTSLLPVAHLTAVGHSVDELRGLIDSFAAVGVRNLLALR
GDPQGGVRQEWVKHPEGLEYAVELVELIGAAGDFHVGVASFPEGHPRAVDLDADTANLVA
KLRAGAEYSISQMFFDVDDYLRLRDRVCAADPEQGAKPLIPGLMPITSLRSVRRMVELMD
SEIPATVLDRLTRAAGDGPEEDRDAVRREGIALATEMGQRLIDEGAPSLHFCTLNFARAT
SEVLANLGMIEQASPAPSIRR
>A0A2E0WCZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micrococcales bacterium|TrEMBL
MTAVQPSLKEVLASGQQVYSFEFFPPKTDEGEQRLWQAIWDLETFHPTFVSVTYGAGGST
RDRTVRVTQRIGQETTMRPVAHLTCVGADEEQLRSVVAEYASVGVANILALRGDPPTGPG
QEWQPHPGGLDYAVELVELVAGLGSFTIGVAAFPEGHPEAKDIDFDVSVLRAKQEAGADF
AVTQFFFDTDDYLRLRDRAAAAGVTIPIIPGIMPVTNVGQIKRFAELSGAVFPKSLAERF
DAIVEDPTSVAELGVSLATAMCQTLLSEGAPGLHFYTLNRSQATKSIYTALGLPQAE
>A0A109HEG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. translucens|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKTYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQASDALSDLRHFKAKVEAGADGAITQYFYNADAYFHFVDA
VRKLGVQVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQALGDDGDAIREFGADLV
AALCQRLLAGGAPALHFYTLNLAKPTISVLSRLE
>A0A1X3CTC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria canis|TrEMBL
MSLPKLSFEFFPTRTPEGRAKQVITRKQLSQYAPDFFSCTSGAGGSTKEGTMQTIQDILS
EGIAAAPHLPCIGMQPQEVVDLLNEYKALGIRHIVALRGDIPSGMGAGMDGLFYANELVS
LIKNEFGNHFHIEVAAYPEFHPQARSAEDDLNNFVRKVKAGADSAITQYFYNTDAYFRFV
DDVQGRGVNIPIIPGIMPIASFSKLTRFSDTCGAEIPRWLRLKLQSYADDTAAIKSLALD
VVTEMCERLLREGAPGLHFYTLNQAGLVSTICQRLGY
>A0A094D333|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4515|TrEMBL
MADSPTTDKLTDKIAALPQDASYFSLEFFPPKTAMGSTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSKELVDDALRAAKEAGIQNILALRGD
EPRGEYKDALEEGKEGEDEFVWAIDLVRYIRKKYGDYFCVGVAAYPEGHADGSHPAEQSL
EHDLPYLVDKVQAGADFIMTQLFYDVDAYDNFEKVLRDHSSGAFKAIPIIPGLMPIQSYQ
ILRRTTKLSNAKLPQSIVDRLDAVRTDDEMVKRVGVDILAEIVESVKATKSRTKGPKGFH
FYTLNLEKAVAFILERANLIPSFTPVLTSDVFAVDDITDTIPLPQLLINGERKNRRQSSV
GSGPHNFVIIDREEASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRPDITSIFVQYINGTLSALPWSDE
PITAETNLIKDELVKLNQKGWWTIASQPAVNGARSQDEVVGWGPKGGWVFQKAFVELFVP
TSDWARLKQLLDGNAEVSFLAQSASGEFLKSKLDLGPGEEGSETNAVTWGVFPGKEIVSP
TIVEEVSFRAWADEAWQMWEEWAAVFGKSGEESRRFLDGVAKDGWLVNVIWHDFVGMCKA
KEGRSEEEGYKGLWDMLIEA
>M1YW24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospina gracilis (strain 3/211)|TrEMBL
MKISKLIETIRPAFSFEFFPPKDDEGFNQLFTAIENLKPCQPVYVSVTYGAMGNTRTKTL
DLVKRIKRDLDLESMAHLTCVGSNSDEIAEVLDALQDAGIENVLALRGDPPKDQEYFVRP
KDGFGFANELVEFIKKRGYDFCIGVAGYPEKHIECSDMNTDLDNLKRKVDAGADFVVTQL
FFDNDYYFDFVDRAIARGINVPIIPGIMPIQNLKQVKRFTKMCGSTIPDPLLLRMEAYSE
DTDAIKEIGVEHATEQCEGLINGGAPGIHFYTLNRSRATLNIFENLKKLVDITPNP
>A0A1F8SJS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_19FT_COMBO_48_23|TrEMBL
MATRFKEALKSSEFVITSEIGPPKGTNIEKMYHHIDLLKDKVVAMNVTDHQSSVMRFPSI
GGCLAIVEHGGEPILQMTCRDRNRLALQAELLFAYTRGVRNVLCLTGDAVPIGDHKEAKG
VFDLDSAQLLRTIRQLESGKDLGGNDLDGAVEFCAGAIVTPEANPIAPQLLKFEKKIESG
AEFFQTQAIYDLDNFAKFMAYARKFPVKILAGIVLLTSARMAKYMTENVPGIFVPQNLID
ELAAAPKGEALNKGIEIAGRMIAALKRDSICDGVHVMAIGREELVPNILTAAGL
>A0A2N0KQE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Ae2-Chloro-G1|TrEMBL
MTKIVDSAFEKTGLPCFICDYSPPRSGVLNGENQPNIEAHFLSIAHSPGQSVRASSSMVA
SKVKSLLNQDVVFTIATRDKNHMALQSELLGAQLLGLENVIVVRGDPAKHENSTVANRTG
GLPTTQVISGISNMNKGRDYRGIALDVPSDFCVGATIDLGRRFSSECNLVLRKIESGAHF
FITQPVFDVPKALKLWEHIESQVITRNHTPIFFGLQILEPDSISFSKVPTSLLDQLQKGK
SHLELAVELYETFRKAGLNNVYLVPPIKKGGTRNYQAAIEVLAKLKSA
>A0A3R8M728|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. 602-1|TrEMBL
MTLPPTRRVIGPVARAGERTYRPRVSFEFFPPKTPAMEESLWQAITRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILDETTLKPAAHLTCVGASRDEVDEVIREYWETGVRHIVSLRGD
PPPGEGGIGGVYVPRADGYANATELTKAVRGIAPFEVLVGVYPEKHPESPSLEHDIDVLK
QKVDAGATLGISQFFFDLDAFLRYVDKVRDAGITIPIVPGIMPVTNFAGLKKMAAACQTA
IPSWLGNLFDGLEHDAETRRLIACSVAAEMCAKLQEQGFEDFHFYTLNRADLVYAICRVL
GVREVSPAPAEAAA
>A0A7C4BMA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldimicrobium sp|TrEMBL
MGRFQRDIKEKDFIFTFELVPGRSIRTKHFTSILRFIEKAPEHDFFSAFSITDNAGGHPA
LSPVALGRTIKNLGLSAIIHITCKDKNRNQLESELLALDRENLHNLLVLTGDYPFYGYLG
RAKPVFDFDSVLLLQMITEMERGIEIPKGAPGGGTKLPPIPFFKGCAVSPFKLTVEELWL
QYLKLYRKLKAGARFIITQVGFSPSAVYQLKLILKNGLTRYFSERLKDENIHKPEEDGQF
KQIPILPSILYLQEGIAKALLKKKVPGILLGKRVWERLKTNSFSEDAVLEVCAKLAVIYK
KMGFKGVHLCGFPANWEVVKHFFKLYNHFSQQIQERENLYYELLNEFDDYVVYEDNGKFV
ERPLANLDTPLPKSRFSISYFVNNIAHQVFFSKVSPLYQVLSKIFTWISRKRSFETLLTS
FEYFVKRPLFHCQECGDCTLWDFNYLCPQSQCAKYLLNGACGGSINSFCEVYPYKKVCLY
VRVLKQGNPRETIRRYLVKDPPYLPPRDWSLYRTSSWLNFYLKRGHFSYED
>A0A7W0CBH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosalsimonas propionicica|TrEMBL
MRVTDFYAGKAPVVSMEFFPPRDEAAAEKFDNIVDTLADRNPDYMSVTFGAGGSNRDGSY
QTVKKLIKDKQLPTVAYIAGYGLGPDEITEVLDNYKALGVETIFVIRGDKPKDENFTPHP
ESFAHASDLIGFIKNRYDFTLGCAGYPEGHLECQSLDKDIEYLKLKQDQGAEYVVAQYCY
DNQFFFDYADKCRAAGVTIPIIPGIMPVYTVKLTNILCRVCGATITDALQKTLDEVADKD
KETVLQAGIDFAVDQCRDLLKHNPAGLHFYTMNRSKSTSAIIDRLREENLL
>A0A7W8EF18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea endophytica|TrEMBL
MALGRPSILPDRVPTVRELLASGGRSFSFEFFPPKTDEGERQLWRAIRELESLRPTFVSV
TYGAGGTTRDRTVDIVERVAHETTLTPVAHFTAVNHSIRELRHLVGRFADAGVRNILAVR
GDPPGDPTAEWVQHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTDYFVQ
KCRAGADYAITQMFFQAEDYLRLRDRVAAKGCTTPIIPCIMPVTQMSTIARSEQLSGAPF
PPDVAARFEAVADDPVAVRRLGIDHGAELCQRLLDEGAPGIHFITFNRSSASAEVFQRLN
HSAVAV
>A0A7V6V516|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MKIKELFDRGMGPLISLEVFPPKANYSLATVFDTLDRLQVLKPDYISVTYGAGGGKQGRT
VEIASRIRSQYGVESLAHLTCVGHN
>A0A7C6P9P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MKEIKPENLKSGSNLEKVLASGQFACTGEIGPLTYATFDNIDKHAEEMRGLVDSVNFTDN
QTAVVRLSSWAASLRLLQLGMEPNLQMVCRDRNRLAMQSDFLGAYAHGIRNVLCLTGDHQ
AFGNHPGCKGVFDLDSVQLIHMLKRLRDELPCIPDGCQRPDGHQLNRERCECHG
>A0A2D9M2V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MRLIRDIYADRQSVDRPVISIEFFTPKTSKGDQVLCESTLPALIRLRPDYCSVTYGAGGS
TKSKTLSVVDMIQRQFGLTAMAHLTCVESSKNDIGAVLDEAKELNIRNILALRGDPPGGS
GEFVKADDGFEYSYELVRFIKANGDFCVGTAGFPEGHIACTEGKHVDWGYLKNKVDCGAD
FVLTQLFFDNDDFLQFRDYIVKKLGVTVPICPGVLPILSTKQISKFTQLCGARIPRALAA
RLKSLGDDDEATTAFGIEYATKQCEELIREGVVGLHMYSLNKAHSTCAIIKNLGLS
>A0A1J0VF14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas aestuarii|TrEMBL
MSTQEHPLGISFEFFPPNTDAGREKLVGVRDALASRSPRFFSVTYGAGGSTQDRTLNTVR
MVRESGVTTAPHLSCIGSDKGELRELLSRYREDGIDSLVALRGDLPSGMGGGGVGQLRYA
NELVEFIREETGNHFEIAVAAYPESHPQAPNFERDLENFARKMKAGADIAITQYFFSAEA
YFHFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIA
AFGEEVISRLCQRLLDGGAPGLHFYTLNQSAPCLRILDNITG
>A0A3P5WYR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium THAF1|TrEMBL
MTRISYEFFPPKSLQASFKLWDTIHTLAATAPDFVSVTYGAGGTTRKLTHEAVTTINKET
GLRVAAHLTCVDASKAETMEIAESYAAAGITDIVALRGDMPGGGAFVPHAEGFASSVELI
EALAADGRFNIRVGAYPDRHPEAASDDADVEFLKRKIDAGATEALTQFFFEAETFLRFRD
RCAAAGIDAPIVPGILPIENWKGVKKFATGCGTTIPAWLEEAFTAAERDGRADLLATALC
TEMCTELLENGVEQLHFYTLNKPHLTRDVVHAMGLAPEPALEKVA
>A0A3Q3K487|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monopterus albus|TrEMBL
MVNQRGGCSRQSCKSDSSGASCSGGESSKESSRCSTPVLDADRCDRLRDKMRRRMESGDR
WFSLEFFPPRTAGGAVNLISRFDRMGSGGPLYIDITWHPAGDPGSDKETSSMMIASTAVN
YCGLETILHLTCCNQTKQKITGHLAKAKHLGLKNIMALRGDPMGADWEEEEGGFNYAVNL
VKYIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVDAGADFVITQLFFRAETFLK
FLDDCRANGIACPIVPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRNYG
IQQAVEMCRALLDSGKVPGLHFYTLNREVATVEVLRQLGLWTEDPRRPLPWAVSAHPKRK
VEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALL
QMWGKELMNEESVYEVFTCYITGQSNRHGHKVTCLPWNDDHLAPETNLLKDELEKVNRRG
VLTINSQPNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSSESVTALLKVLKKYEPRVNY
HIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKL
YEDESPSRMIIKYIHDNYFLVNLVDNDFPLRSCLWQVLDDMLELLDAPPEPLTAMEQSE
>A0A435W410|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.001.02.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A329BDZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirgula sp. AG722|TrEMBL
MSSVKPTISFEFFPPKTEEGHARLATARKQLAHFKPAFFSVTFGAGGTTREGTLRAVLDI
RDAGYAAAPHLSCIGSTRDNIRSILDEYREKGIRHVVALRGDIPSGMGEVGEFRYANELV
SFIRDTHGDHFHIEVAAYPDYHPQAVNARADLDAFAGKVRAGANSAITQYFFNADAYFAF
VDEASARGVDIPIVPGIMPIYNFSQLARFSDLCGAEIPRWLRLKLQAYGDDVASIRALGL
DVVTELCDRLLSNGAPGLHFYTLNAAGSVSTLCQRLGL
>A0A4V1BHF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia sp. CS682|TrEMBL
MTFDNARGRSTPGRPPRTHPNVSGTPSVVQSLRAHAGAAVPFSVEFNPPRDAAAEARLWR
AVRQFERMHPAFVSMTYGAGGSTRDRTVRVTGELAQETTLLPVAHLTAVEHSLGELRSLV
GSYADSGIRNILVLRGDPPGDPLGEWQQHPEGVAYAEELVRIVRDLGDFHVGVASFPQGH
HRSPDLDSDTAFLAAKLRAGAEYSITQMFFDVEHYLRLRDRIAKFDPIEGAKPIIPELMP
ITSLRTVARAEELCGRALPAAVLDRLNKAAGDAPDDNQAAVREVGIEIATEMAQRLIDEG
APCLHFITLNFAKATTEVLTNLGYGVTAAPISA
>A0A1H0ZR54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. 374|TrEMBL
MASSASLNLADARALLLSPLGPVARAGSNRDAVRISFEFFPPKTDEAEANLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIITETSLRPAAHLTCVEASRDEVDEVIEGYKAIG
VDHIVALRGDPPGGAGIGGVYQPRADGYANATELTAAISRIGGFDVTVGAYPERHPESPS
IDHDIEVLKTKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLQ
RMCGACGASIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETAADQ
>A0A2A7U910|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia sp. FDAARGOS_372|TrEMBL
MTFDPAPPHAAGTPSVVQSLRAHAGRSVPFSVEFNPPRDAAGEARLWRAVREFERMHPAF
VSMTYGAGGSTKDRTVRVTGQLAQETTLLPVAHLTAVGHSVAELRSLVGAYADSGIRNIL
VLRGDPPGDPLGEWHKHPEGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLATDTAF
LAAKLRAGAEYSITQMFFEVEHYLRLRDRLAALDPVEGAKPIIPELMPITSLRTVTRAEE
LCGRPLPAAVLDRLRRAAGDGPEEDRAAVREVGIEIATEMAQRLIDEGAPCLHFITLNFA
KATSEVLTNLGYGVTAAPVRA
>A0A0F9HBB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MNLAEKLKSGKFLITAEIGPGKGTDIDEYLEEMEILRGKVDAINVTDLQSSVMRLGSLVV
CHLLAERDLEPVFQITCRDRNRLALQSDLLSASVLGIRNVLVLTGDHTVLGDHPEAKPVF
DLDSVSLLKVASTLAEGKDMKGNDLKGTPEFCLGAVVSPGADPLEPQLIKMEKKIEAGAK
FFQTQAVYDRESFEKFIKKAEKFGVPIMVGIVLLKSAGMARFMNANVAGVSVPDKFIKIM
AEASKEERPPKSIEIAASLIKEMKGMCQGVHIMSLGWDKYVPSVLEAAELI
>X1L2H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKKKKESEGKKMGDEVYSDLMRELKEGEYVFTGELEPEKAGDVNEPIEMAKELVGLVVAC
NVTDNPQSMAYVNSMAASYLIQKETGMECVYQLRCSDRNRMALLSDVLGAGALGLKNILA
LAGDHVSLGDTPDAKPVFDLDSTTLIAMIRKIVDEGKDLGGNEIHNPPKLHVGGAAAPGA
AHLKAEVAKVKRKINVGVEYLQTQVVYYTDVLDKFFNELGKVDVPILVGIFPARTFGQAD
FFD
>X1PAU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
STFGVNNILCLSGDPVSFGNCPEAKSVFDLDSIQLIRMVKGLRDEKKFENGEPIAGREPR
LFIGAVTNPFADPTEHEVIRLGEKVAAGADFMQTQSVYHIKKFERWMEMVRERELPKKVK
ILAGITPLKSVAIARYMKTKLSGVDVPDELIERLRKATTREQVRKEGIKIAVETINSLKE
IEGVAGVHIMAIEWEEVIPEICEASGLYPRFSLEEVGRQ
>A0A7G2LTA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp|TrEMBL
MTTPAVSFEVFPPRTVGAAFKLWDAAQALAPLAPRFFSVTYGAGGTTRDLTHDSAHVLHR
TSGLPVAGHLTCVGASRAETMDVADKFAEAGIKDIVALRGDPQAGTDKFTPHPEGFADSC
ELIEALAKTGKFTIRVGAYPDPHPEAADQQANIDWLKRKFDAGADEALTQFFFEAETFLR
FRDACVKAGIDKPITPGILPVVNWTSARKFAVKCGTPIPEWVDQAYEAAIRDDRHDLLAQ
AMCTELCSDLIDEGVDALHFYTLNRAELTRDVCRAIGVTPQVDLSDVA
>A0A859QFP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer mexicanus|TrEMBL
MTTRTLYPAERGNLRLSFEYFPPKTDEMEVQLFQTVADLSVFDPAFVTVTYGAGGSTKAR
SLTTVRRMIGEMGIGNTAAHLTCVGAPKAEVDAVIEEFLAFGVRHFVALRGDPQGGIGSA
YQPFPGGYENAAALVKALRARGDFEISVSAYPEKHPESPDVAADIDMLKRKVDNGATRAI
TQFFFDNDDFERYLEQVRRAGVQVPIVPGILPINNLAQVQRFAGLCGARVPEAVISRLSH
LEDQPTERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLVTAVCDLVGFERMPVQETA
VELPIRASA
>A0A7Y3HV00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceitalea sp|TrEMBL
MKVTDHIKKAKGETLFTFEIIPPVKGKSIQELYNNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTLGICASITHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMREQKYFEATKGGHPYASSLVAQIKQLNDGKYLHEVIETDNCANFCIGVAGYP
EKHMEAPSMKSDLKRLKEKVDLGADYVVTQMFFDNEKYFEFVDAAKFYGIDVPIIPGIKP
IAVKRHLQLLPQVFRVDLPQDLIDAVEGCKTNKEVRQVGVEWCIQQSKELKRAGVPVLHY
YSMGKSDNIKAIAKEVF
>A0A0F9BXS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MTTPAVSFEVFPPRTVGAAFKLWDAAQALAPLAPRFFSVTYGAGGTTRDLTHDSAHVLHR
TS
>X1VIG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
VDNELKGKPNFFPGAVVNPGADTEAAFELQLIKMEKKIAAGARFFQTQAIYDFDAFARFM
KRAEGFNIPILAGIIPLKSAGMARFMNKNVAGVFVPEELIDKMAKTEDKARTGIDIAANL
IKELKGMCQGVHIMAIGWEKRIPAILDAAGL
>A0A6N7IZ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Weimeria bifida|TrEMBL
MSKISDLAQQQIILADGAMGTYYQSLYPDDENIVEMAVLDNPDRIKNIHKSYIDAGAVLI
RTDSFACVGPFIESDELKAEIASKSYELAREAAKESGRDVIVAADIGTLFDPAMEGHILS
DIKPVLDAFLAAGADVFDFETQTQTEGLSEIFSYIKEKNPKAQIIVTFSVNKNGMTTGGL
SADNIMQFGASEENIDAFGFNCGVGASHMADIIKKVSFYTDKPFMVLPNAGYPYNLRGRQ
IFSGDSSFFTEKMKDIVSSGADIIGGCCGTTPEFIKKLGETFSGKKSGERKIVEAFDKKT
RTFSSFYKKLVNDEKPIVVELDPPFGSDITKVMNSARTLSKADVDIITLSDSPMGRSRMD
PMLLGAMMQKETGTDVMPHVACRDRNLIGLRGCLLGSYAAGLRHFLMITGDPVPAADRSQ
VTSVFDYNSIRFMNMAKLLNEDDFSADRIVYGGALNYHGRNAEAIARRMKLKMEQGCSFF
LTQPVYGDDDIERLSLLKKMTGAKIIAGIMPLVSYKNATFMANEMPGIHVPESIVNLYSP
DMSREEAEKVAVSVSLDIADKMREMTDGYYFMVPFNRVKLICDIIKQIRK
>A0A679FAM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylosinus sp. C49|TrEMBL
MSDNRSLWPPGHFDISYEFFPPKTPEMEAQLWDSIARLAPLKPKFVSVTYGAGGSTRERT
HNIVARLAAETDILPAAHLTCVSAARAEIDEIVRDYWNAGVRHIVALRGDPPTGVGTRFE
PHQQGYRSSTELVRGIRAIGDFEISVSTYPEGHPESRTIDDDLDALEAKIDAGATRAITQ
FFFENDVYFRFLDKARARGIKIPIVPGIMPVQNFKQTANFARKAGASVPDWLAHRFEGLD
DDPVTRRLIAAAVAAEQVLGLAENGVREFHFYTNNRADLVFAICHLLGVRPVTEKAAA
>A0A0F8XI37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MNAPSNSPLGNRADGREDLLATALATELCSELVENGVEDLHFYTLNKPHLTRDIAHALGI
TPETVLEKVA
>A0A8H4VHT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrocybe pediades|TrEMBL
MKISQKIQQSSKDDKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPKEKVDIALKDAKQHGCRNVLALRGDPPMGKDE
WEAVDGGFVHGIDLVKHIRKNYGDYFDIAVAGFPQHMSLPPEDLANEIRWLKEKIDAGVN
FIFTQMFYDVDLFINWVKAIRAAGITIPIVPGIAPIQTWNGFQRATSLAKITIPQSFRDA
LEPVQNNDEKVREIGTKLVADMCRKILDADIGVRGLHFYTMNLEKGTKMLLEELNLVPRI
ETIKPLPWRQSLTPNRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGHPETMADLSALFVKFCMSELKALPWSDQAPSIETSVIAKQLA
QINELGFLTINSQPAVNGARSDDKVFGWGPSNGYVYQKAYLEFFVNPTLLSLLITQIERD
SNITYYVINRRGDLRTNNHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGAQ
WAKLYEHDSPSQKLISDFVETSYLVNVVHNDFHDPDAIFKPFYKAGAEYLALKSKTTAVN
GH
>X0ZX65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MHQVHRSEVQFYSDLYKSSAVGIKNILCLTGDHQSFGNHPGAKGVFDIDSIQLIQIIKNM
RDEGIFQNGDEILARNPDVFIGAAANPYADPFELRVDRLRKKIKAGADFIQTQSVYNLDK
FNRWMDEIHSNGLDKKIHILAGVTPLKSLRMTERMKFHVPGVDIPDTIYSRMKNAADPKS
EGYEIAIELIKELKKINGLHGIHITALFWEDIVPSLVKETGLYPRSSF
>X1MEF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
DVPDELIERLRKATTREQVRKEGIKIAVETINSLKEIEGVAGIHIMAIEWEEVVPEICEA
SGLYPRTSLEELGRQ
>A0RPC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter fetus subsp. fetus (strain 82-40)|TrEMBL
MLKKKIKDNTPGILLYGLTPPKLNLTHEEAIIVAKKQLERLENRGIDGLVIYDLQDESNR
NKSERTFEFCGTIKPEIYHKEFLKLAYPAVIYKAVGNYTQDEFCRFLNDSGENLSVFVGA
SSKKDSPKLSLDMAYKLKKEQGRDITLGGICIPERHEKKGDEDLRVAGKTIKGCEFFITQ
AVYNLENAKRFLDDYSNLNIKKVPIIFTFTPCGSLKTLEFMRWLGISVPKQFENRLFKSD
DPLKASISLSLDMFEFLFKYGKAKGISIGANVESISTRKVEIEASVELVNGIKSIIS
>A0A4Y1RWA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prunus dulcis|TrEMBL
MGVIEKIQEALLEEKKVLFSFEFFPPKTEDGVENLLERMERMVAHNPAFCDITWGAGGST
ADLTLDIANKMQNIICVESMMHLTCTNMPVDKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQIQGGFACALDLVTHIRAKYGDYFGVTVAGYPEAHPDAIGTDGLASPEAYQSDLAYL
KRKVDAGADLIITQLFYDTDVFLKFVHDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPAEVTAALEPIKDNEEAVKSYGIHLGTEMCKKILAHGIRTLHLYTLNMEKSALAILMN
LGLIEETKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDLYPHGRWGDSRN
PSYGALTDYQFMRPRARDKKLVEEWVVPLRSVEDIHEKFKKFCLGKLRSSPWSELDGLQP
ETKIINELLGKINTKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKL
NALVEKCKALPSLTYMAVNKDGRWISNIGQTDVNAVTWGVFPAREIIQPTVVDPASFMVW
KDEAFEIWSRGWACLYPEGDSSRKLLEEVQNSYFLASLVDNDYIQGDVFAVFADF
>I4JZM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens Q8r1-96|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDASSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1F7SXA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Tectomicrobia bacterium RIFCSPLOWO2_02_FULL_70_19|TrEMBL
MSLVTESIRSPGLTASIELFPPKGEKAAGRVLREVEEIQAGMEVAFTSVTYGAGGSTQDG
TLELVLALAQRHPGRVVAHLTCVGAGEGDLGALLALYLKSGMRDILALRGDLPEGMTPEQ
AAAGGFRHAVDLVRYLRKLGGFASVGVACFPEGHPETPDLAAHLAHFAEKAEAGGDYAVS
QFFFEAHLWERFLEACERRRIGIPLAPGIMPVRDLEQLLRFAARCGATVPKSVVNALARY
KDDPESFKERSADLAAGQVERLKALGVRHVHIYSLNKSDIILKIADRLGWRKKAPAK
>A0A504LBN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B1-1-5|TrEMBL
MTVRQIDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFRTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHLLHDEITETQVDMVK
TAH
>A0A6N8A389|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium sp. RKSG952|TrEMBL
MTTTIPFAARRSRQTAVAPITASFEFFPPKSDKMAANLWETVQRLEPLAPSFVSVTYGAG
GSTRERTHTTVERILNETGLAPAAHLTCVGSPKSEVDAIVRDYWDLGVRHLVALRGDPLE
GIGARYKPHDEGYAYASDLVAGIKNIANFDISVSGYPEKHPESGNWQIEIDNLKRKVDAG
ADRIITQYFFDNDLFDDYLDRIAAAGINIPVVPGILPIHNFEQTMVFSAKCGTSIPDWLA
RRFAGLKNDAETRKLVGVSIACEQVMDLVDRGISDFHFYTMNRADLTYAICHMLGMGHQA
PEKVAA
>A0A7Y3I5Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHVNEIFERDSTTFSFEFFPPKSDEAWGLLFERIRVFKRLAPSFVSVTYGAGGSTREQTH
DLVVRLHEEAGLDAVPHLTCVCHREAEIDGVLRRYADAGISNILALHGDPPRGMVGYDRS
QDDFKYAADLVRHIRVFNERGEHPHPKGFGVGVAGFPEGHPETLNRLREMEYLKAKVDAG
ADYVCTQMFFDNNEFYDWRERCELAG
>A0A809EAX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia solanacearum|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNARAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRSILDTYREHGIRRLVALRGDLPSGMGEIGEFRFANELVEF
IRKEMNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>A0A7C2FKP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MKSGSRLEKVLTAGKFAVTAELGPPQNANPDAVKKKAEYCKGNCEGANVTDNQTAIVRMS
SMAASVIALSCGVEPIMQMVCRDRNRIAMQSDILGAAALGIKNLLCLSGDHQGFGNQPEA
KGVYDIDSTQLIAMVKQMRDDKQLISGDEIKEYEPRLFIGAVANPFADPFEYRVLRLAKK
IEAGADFIQTQCIFDMERFEKWMELVVAEGLHEKVYILAGLTPVRSHKALIYMKNNVAGI
SVPDELIARMEAAEDKKQEGIDICVEMIEKIKTIKGVAGIHLMPIGWESITPTILEKAGL
LPRPEV
>A0A7C1Y4U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MKSAGRLEKVLTAGEFAVTAELGPPQNANPEAIKKKAQHCIGNVEGANITDNQTAIVRMS
SIAAGAIALSCGVEPIIQMVCRDRNRLAMQADILGAAALGIQNLLCLSGDHQTFGNHPDA
KNVYDIDSMQLIAMVKKMRDDKQFLCGDDIKEHEPKLFIGAVANPFADPFEFRVMRLAKK
INAGADFIQTQCIFDMKRFGDWMKMVVDEGLHEKAYILAGLTPVRSHRALKYMKNNVAGM
SIPDELITRMESAEDPKEEGVKICVEMIEQIKSMEGVSGIHLMPIGWESITPTILERAGL
LPRPKV
>A0A7C6XL18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp|TrEMBL
MSQSTLRRLLSTARYEVLPTAGIVERVEEYVAPGREITVTASTGLTLEATLSTAEQLQAL
GFRAVPHLAARMIHGRPELTEIVDRLAEAAVDRIFVPAGDATPPAGGYVGAHDLLVDLSS
MAAPFQHIGVSAYPESHPIIPDDVTVQAMWDKRDYATHLVSNLCFDPAAVASWVARVRAR
GIELPLVLGIAGKVELAKLARVATKIGVGESTRFLRKNTTTFTRMAKPGGYNPRKFLDKI
GP
>A0A419EIP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MTNKFLDLLSSQTLLADGAMGTMLHGRGIGFDKCFDELNLTNPAAVADIHREYIEAGAQL
VITNTFSANRFKLEKHGLEKRLVDINRAGVELARRAVSASFRDVLVAGDVGPLGVRIAPY
GRVQPDLARAAFAEQISALADAGADLIVIETMTDLYEIKEAIRAARDVGAQGLAPLPVVA
SVTFTRDDRTILGDDPAKVARTLAEAGADVIGVNCSGGPAQLLRILKAMVAAVVGRGDSL
SRPYMWVKPNAGWPEQVGGRIMYPADAEYFGEYALSFREAGANVVGGCCGTTPAHIASMR
RALDSAAAPAPMTVTPLPVEEEALEGAQPESELAQKLAAGKFVISIEMDPPRGLSTHKLI
AGASLLHDAGADVINVADSPMARMRMSAWAVCEVVQRQVGVETTLHFPTRGRNLLRVQGD
LLAAHALGIRNVFVVMGDPTAIGDYPEAMDNYDLVPSGLIKLIKQGFNAGVDHSGTSIGQ
PTNFFVGAALNLVPSDMATEFKNLTRKVKAGADYFLTQPIYRAEDGEGFLAKYELQHGAL
NKPVLVGILPLVSAKHANFLNHEVPGISIPEEAIARMEAAGEDAAKVGVELAVELIQKVK
PWAQGVYIMPQFHRYDLVAEVVERVKG
>A0A7C3Q1V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHIRDIFAQHSATFSFEFFPPKSAPGATDLFSSIQELESLRPTFVSVTYGAGGSTRDVTH
DLVVKLKTTTSLDPVPHLTCVCHDDRDMEAILTRYAQAGISNIMALRGDTPRDLPAGVEP
WRTFKYASQLVRFIKKFNEKGIHPDRRGFGIAVAGFPEGHPETPNRLLEIERLKAKVDEG
ADVIVTQLFFDNRDFYDFRSRCEMAGIRIPVIAGIMPIGSLAGMKRMADLALGARFPAPL
IRSINRTGGDEESVRRVGIHWATEQCRDLLDHDVAGIHFYTLNKSTATREIYATLGVKDS
RGLAG
>A0A7Z9PVK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MSNFLEELKKRVMVTDGALGTRLQALTGNSQSCIDGFNLDPSYSEIVSLVHRSYVDAGAD
IIFTNTYGANGIKLDRYARKNQVLAINEEGARLARKVAGDSVFVAGSIGPLERPGGMEAH
FEEKLEEVFQEQLQGLANGGVDLFVFETFQDIVEARAALSAAQNFDQPVVFSIGGVTNGR
TSLGTTVEEFVVMASGFGVDVIGVNCRGAFDILESVERISQTTSLPLIAMPNAGSPEIDR
GRVAYRAEPHFFKDYASRLFEAGVSIVGGCCGTGPEHIRQMAEVAVNTKPPAPRAVSNVR
VISHSTVIEPGPVKVSQVEQVFKEVPFVISVEMRAARAGAFSDFIDAGKALARQGVHLFD
VPDNAGAKVTMDAMVSAFRLQEETHIPTIMHLSASHRNLIATQSYLLGCHECGIQSVLAV
TGDHPNVGDHDKYASRVNDIKSSVNLLKLIGGLNRGKLFNGSECQRTSIFAGAGFNPMRN
LTPQLKWLEKKVDAGAKFIYTQPLYCEDDV
>E9UTY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium Broad-1|TrEMBL
MDLQQRISDRAGEILLFAVTPPRVTTDPERVQQIAEVTLERIRPLDVDGLILYDIDDESD
RNPEERPFPFVRTLDPAEFLERNLAGLDVPAVVYRATGKYDESTLRDWVKTQDPARALSV
FVGASSGEKRVSTSLRRAQEIRRETNPDLLLGAVAIPERHTAKGDEHLRLIAKQEAGCSY
FVSQVVYDVNAAKNLVSDYRYECETRGLQPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENELRHATDTLDASLEQAEATAIELMSFCRQLGVPFGINIESVSIRKVEIEASVRLAERL
RGKLER
>A0A349UKY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MQHHIDKKMFHIEILSPKQKSQKLEEDLASFADKYRRAFDAGHVICIPDNPMGNLAFQGV
ELIRELGLPVHPDQVSVHINTFHTKRDLDAMLTTACDLGISHMLVISGDGSPRLPKLTGK
ELGYDVEAVTSVELLRYIRREYPGKFHIGVAFNPYEPQDHEVEKMHRKVDAGAEFITTQP
VIESHPAVESLWQFGLPVVIECWMSKKIHLLSECVGYEIPEDTPYDPVANLQTLMAKYPK
CGFYLAILGFKTQFPILKDVWK
>A0A4Q9Z2K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium silvisoli|TrEMBL
MKVTQHIANANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEYKE
LPNGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKTETYFRPEKEGNEYATELVTQISNLNNGIYLDEDLKNSASTNFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGADYIITQMFFDNRKFFDFVDKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSVELPDDLIMAVVKAKDNDHVKQIGIEWCIQQSKELVAAGIPVLH
YYSMGKAGNIKSIASSIF
>A0A1I3Y783|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. UNC279MFTsu5.1|TrEMBL
MTLPPLRRVLGPVARAGERTDRPRVSFEFFPPKTEQMEENLWAAIKRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRAEVDEVIREYWETGVRHVVSLRGD
PPPGEGGIGGVYVPREDGYRNATELTSALTAIAPFNVLVGVYPEKHPESPSIEHDIEVLK
AKVDAGATLAISQFFFDTDAFLRFVDKVRKAGITIPIVPGIMPVTNFKGLVKMSAACQTA
VPGWLANLFDGLDEDADTRRLIACSVASEMCAKLQEQGFSDFHFYTLNRADLVYAICRVL
GVREAASAPSPVSAEAAA
>D4TBU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. aurantifolii str. ICPB 10535|TrEMBL
MSPNHHDKTARPVIPTDTPSGASTITDAYSLEVSVKDIGALTNAAPGILPGCAMFIPYLP
GQTEAARLAAAQMVRRLGFEPVPHLSARRIGSLEELQAFIARLVGEADVTGCLVIAGDPS
TPKGPFADSVSLIETGVFERSGIRTIGVAGHPEGHPIMRTTEQWDVLQRKCRSIQERGMA
PLIVTQFGFDADIVMTWLEALRARGMTHPVRVGVPGPASVGTLARYAASCGVGACASVLS
NYGVSIGKLFGNAGPDRFVDHLVGRLTEAHGDVRLHLYPFGGIAQSVEWVAHYRSCKASQ
DRVSSVAAD
>A0A5Q2N2D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heliorestis convoluta|TrEMBL
MTRIVVELVPRTEEVLRGELETIQNHFPIVEGINIPELLRFDIRSWDACAIVKDFYQKAI
PHIRSIDINPQEPLPMAERLVDLAIQEVLVVTGDPPADMRSKVYPCNSIDMIKKFKRELP
HIKVYAAIDPYRKSISKEADYIKRKIDAGADGFFTQPFFDLRLMEIYGELFQDTEVYWGL
SPVTSEKSVSYWETKNHVVFPRDFAPTLEWNVDFARKALQFARQQGGHVYFMPIRLDVKS
YLQGVFA
>A0A3N4E9F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella psychromarinicola|TrEMBL
MAFHHAQHAQSLNQSLSELNDINVSFEFFPPSTPAMEEILWNSIRRLEPLNPKFVSVTYG
ANSGVRDRTHSVIERIQKETNLVAAPHLTLVDASDEELVELAKHYWKSGIKDIVALRGDL
PDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDARNAQADLIHLKKKIDAGANRAI
TQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVTNFKQTKRFADMTNVAIPHWLHRQFEG
LDDDAATRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A059DUL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp. CY54-11-8|TrEMBL
MSTSTPHVSFEFFPPKSDAMANRLWDTVQRLEPMAPDFVSVTYGAGGSTRERTHETVKRI
AQETSLKPAGHLTCVSATKAEVLAVAEEYWQAGVKHIVALRGDPPSGMGAKFEVHPGGFR
DAVDLVKGLREHRPELGKCFEISVSCYPELHPESQGWEAEIAYLKAKQDAGADRAITQFF
FEPETYLNFLDKARAGGVTMPIVPGIMLQANFRGLQRISGLCGATIPDWLADLYDGLDDD
EETRELVTANVAADLCRKLAEQGVQNFHFYTLNRAGLALSTCRLLGLKPHPAEAA
>A0A543JBU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix saharensis|TrEMBL
MTSVVERLRTGSPVFSVEFFPPRDEAEETILWRAIRELEPFDPAFVSITYGAGGSSRDRT
IRTTGRVAQETTLLPMAHLTLVNHSVAELRNVIGWYAAVGVRNILAVRGDPPGDPNGEWV
AHPEGLTYAEELVRLCRELGDFCVGVAASPYGHPRSADLDTDTEYLVRKLRAGADFAIAQ
LFFQPEDFLRLRDRVAARGCDTVLIPGLMPLTTPRTLAKTIELSGSSVPDVVARRLDPYA
DDPTGFRKAGIDLMTEMGERLLAEGVPCLHFYTFNRSKATREIVGRLGLVPARAV
>A0A2T0R4A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineococcus rhizosphaerae|TrEMBL
MSLVADLRTARRRFSVEFSPAHDEATAARQWRAVERLAPLGPLFASVTYGAGGGDRDGTV
ELAGRLARETPLRPVAHLTAVGQPAVALGRVVDDLLARGVRDVLALRGDPDGDPRAPWTP
HPEGFQHADQLVRLALEHGVDSAGVAAFPLGHHESPDLETDLRHLLGKVRAGAGWAVAQL
TYDVEDFLRLRDRLVAAGCDVPLVPGLLPVTSPRVLEVTRRLTDGHEPSWLHRRLAPLLD
DRGAFREEGVRVAVEDGRRLLAEGVEVLHLYSLNAASNVETLVRELGLAAPSAPAPTSQG
TAEEGSCRTPVVP
>A0A4R8HT83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylosinus sp. sav-2|TrEMBL
MMSDNRSLWPPGHFDISYEFFPPKTPEMEAQLWDSIARLAPLKPKFVSVTYGAGGSTRER
THNIVARLAAETDILPAAHLTCVSAARAEIDEIVRGYWNVGVRHIVALRGDPPTGVGTRF
EPHPQGYRSSTELVRGIRAIRDFEISVSTYPEGHPESRTIEDDLDALEAKIDAGATRAIT
QFFFENDVYFRFLDKARARGIKIPIVPGIMPVQNFKQTANFARKAGASVPDWLAHRFEGL
DDDPVTRRLIAASVAAEQVLGLAEGGVKEFHFYTNNRADLVFAICHLLGVRPVTEKVAA
>A0A3Q7P8A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callorhinus ursinus|TrEMBL
MDHPTPKVLPARPRGPSLGMWALETGRVRFSVPPSISRNPAMVNEPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQEQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGVTCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYLS
GEPNQHGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPTPEQGEEAL
>A0A425WH12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MADGAMGTYYQSLYPDDENIVEMAVLDNPDRIKNIHKSYIDAGAVLIRTDSFACVGPFIE
SDELKAEIASKSYELAREAAKESGRDVIVAADIGTLFDPAMEGHILSDIKPVLDAFLAAG
ADVFDFETQTQTEGLSEIFSYIKEKNPKAQIIVTFSVNKNGMTTGGLSADNIMQFGASEE
NIDAFGFNCGVGASHMADIIKKVSFYTDKPFMVLPNAGYPYNLRGRQIFSGDSSFFTEKM
KDIVSSGADIIGGCCGTTPEFIKKLGETFSGKKSGERKIVEAFDKKTRTFSSFYKKLVND
EKPIVVELDPPFGSDITKVMNSARTLSKADVDIITLSDSPMGRSRMDPMLLGAMMQKETG
TDVMPHVACRDRNLIGLRGCLLGSYAAGLRHFLMITGDPVPAADRSQVTSVFDYNSIRFM
NMAKLLNEDDFSADRIVYGGALNYHGRNAEAIARRMKLKMEQGCSFFLTQPVYGDDDIER
LSLLKKMTGAKIIAGIMPLVSYKNATFMANEMPGIHVPESIVNLYSPDMSREEAEKVAVS
VSLDIADKMREMTDGYYFMVPFNRVKLICDIIKQIRK
>A0A7U9N8I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKVSEIFNVKKSQGKPVLSFEIFPPKKEEALKNIDATLERLCDLHPDFISVTFGAGGSAV
DNQTVEIAKKIKNNYGVEPIVHLTCLHYEKEEISALLGQLSEAGIENVLALRGDVNPNVP
MKHDFRYANELVEFIKKQGDFHISGACYPETHLEAPCAVTDIRNLKKKVDAGASHLVSQL
FFDNEAFYRFYEKTRIAGIDVPVEAGIMPVTNKAQIERMVNICGATLPKKFEKILHKYED
HKEALFDAGMAYAINQIVDLIANDVDGIHIFTMNNPKVAGRICDGIRNLI
>A0A351V8I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MIIKNLFKEKKPVISFEIFPPKKEAELENIDETLRTLARLHPDFISVTFGAGGSGANNKT
VELAKKIKENYGIEPLVHLTCISHSKEEIKKILGQMEEAKLKNVLALRGDVNPNVPIKDD
FKYASELVSFIKEQGDFHVSGACYPEVHLEAESEVSDLRNLRKKVDAGAEHLVSQLFFDN
DVFYDFLTKVRIAGIDTPVEAGIMPVTNKAQIKRMVTMCGASLPDKFERIMEKYGENKEA
LFDAGMVYAINQIVELISYGVDGIHIFTMNNPVVAGRICDGIKNLI
>A0A373CXV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium OF11-28|TrEMBL
MNLREYLKTTNLITDGAFGTYFAAKYQTQDIPELANITAPEKVKKIHEEYLNAGAKFIRT
NTFASNKETLQEDFAEVEKNIQAAVEIARDAVNGRDAWIAGDIGPIPVNGAEDAAAAADE
YYQIAKTFAERGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVSEIDAVGLNCGVGPAHMRQILEKAGRSGDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIGEISSRDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLSVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTEEDAARLRRIKEETGAKILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>A0A6G9RS03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyvera genomosp. 3|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A2R6CJU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QH_10_65_19|TrEMBL
MLTNRAKTELLADPRFELMPFDSIEKQVSHLPDDATITITASPSLGLEDTVTWAENLAED
GYEVIPHIAARYVESEDHLDEIANRLDAAGVTAMFVPGGDREEPVGEFDSAYQLLTSLDD
LGHEFDDIGITGYPEGHQFLDNEELAESMEQKAPYATYIATQICYDPEAIVDWIDLIRDE
RGIDLPVDVGIPGVMKYQRLIGISRKVGVGDSVRFLQKTTGILGFLREFIGSRGKYEPDD
LIDGLAPYTDDPHYNIRGLHIYTFNQVPDTEAWRTGRLEA
>A0A374DBR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM36-2AA|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPGTIEHLMKYKPEYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLEQYLAEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A085DU96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. SUBG004|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAARNPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIREETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GTDVVTRLCERLLDGGAPGLHFYTLNQAAPVLKVVDNLR
>A0A3D2JLV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
EEGIAYTVRLMEQYIAEGIDGIHLYTMDRSEDVREVLQRAGLR
>A0A1S2QCH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces monashensis|TrEMBL
MALGTASTRTDRARTVRDMLATGKATYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGQWVPHPKGLTYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCDTPVIPEVLPVTSVKMLERLPKLSNAVF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A355VZ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIRDILNKDTATISFEVFPPKKSTDFGNVEAAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGEIQKQHNVPTVAHLTCVCADRSSIGAALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKKNGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIIPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNLSEILKA
>A0A5P9KRT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. Bb-A|TrEMBL
MTGSSTNLAEARALLLSPLGPVARAGSNRETVRVSFEFFPPKTDEAEVNLWKAIRRLEPL
NPAFVSVTYGAGGSTRERTHRTVQRIIAETALRPAAHLTCVDASRDEVDEVIAGYKAIGV
DHIVALRGDPPGGGGIGGVYQPRADGYANATELTAAISRIGGFDVTVGAYPEKHPESPSI
DHDIEVLKAKVDAGATRAISQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLVR
MCGACGAGIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLHEEGFSDFHFYTLNRADL
VYAICRVLGVRETKAVA
>A0A2S7JBS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax sp. TS-BS-61-7|TrEMBL
MLTNDRIPLSLEFFPPKTPEGAEKLRGVRQQLYTLQPEFCSVTFGAGGSTQEGTFNAVRE
ILAEGVSAASHFSCIGATKDTVRAQLATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDL
VAFIRAETGDDFHIEVAAYPEVHPQAKSPAHDLQAFAAKVKAGANSAITQYFYNSDAYFR
FVEEVDALGLEVPVVPGIMPITSSTQLMRFSDASGAEIPRWIRLRLQSYGDDVASIKAFG
LEVVTDLCEQLRAGGAPALHFYTMNQSAATLALCKNLGLSA
>A0A3C1J541|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIRDILNKDTATISFEVFPPKKSTDFGNVEVAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGEIQKQHNVPTVAHLTCVCADRSSIGAALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKESGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIVPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNLSEILKA
>A0A3D3IZG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MIKDIFGSKPCVLSFEVFPPKKDDDFEGVFRTIDELAELKPDFISVTYGAGGSNSKKTLE
VASYIQNEKKIEALCHMTCVGYTKADLDKALDDFDSSSLNNMLALRGDRPLSMTDEVFNN
REFMYANEMVKYLRDKKGDSVTIGGACYPEKHPESSSLQEDIKHLKMKVDAGLDFMTTQM
CFSNDIFYRYFNLLETNGIDIPITCGIMPITKAGQLGRSVTLSGSSVPKELADIIALHGD
DPDEMFKYGTQYAAYQIRNLMTHGVQGIHIYAMNNAKTVKAILDLI
>A0A177RDJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomyces sp. SCGC AG-212-M04|TrEMBL
MTVLRQIFETKPFCLSIEIFPPKSADADASLWENLERLMPYGPSFVSCTYGAGGSTRNRT
VELCREIRSRFNVPATAHFTCVGSTVQELTDWLGDAKAAGIQNFMALRGDPPKGQEGFRP
VDGGLRYANELVSLIRKTAPQAGIGVAGYPEKHPEAANPDVDLTNLKRKVDAGADAVFTQ
LFFDNAAFLRFRDQCRAAGIKVPIVPGIMPITEFARIKRITQMCGSVIPASLASRLESVQ
DDLAAQFEIGVEFAIDQCRELCREEVQGIHFYALNRSSACERILDALDLPDGARTRAAV
>A0A4R6AUG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fluviibacterium aquatile|TrEMBL
MTTPRISFEFFPPKSLDASFKLSETVRMLAPLDPGFVSVTYGAGGTTRKLTHEAVVAIHK
NYGLNVAAHLTCVDASRAETLEIAESYAAAGVTELVALRGDPPKGSGGFVPHPQGFNNSI
ELIEALAETGKFKLRVGAYPDPHPEAVSANADVEYLKRKIDAGAHSAITQFFFGAETFFR
FRDRCAAAGITAPIIPGIVPIDNWKGVRKFAVACGTVIPPEVDAAYETAIRDGREADLSI
AMCTELCSDLMEGGVEDLHFYTLNKPNLTRDICHALGVTQAATLENVA
>A0A836UGV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTEHIKNAKKTLFSFEILPPLKGTSIESIYNSLDPLMEFNPPFIDVTYHREEYVYKKR
KDGLLERRSVRKRPGTVGICAAIMNKYNVDTVPHIICGGFNQEETENALIDLDFLGVDNV
LVLRGDPIKSETYFTPEEGGHSYASELLQQVDGMNKGIYLDEELKNSAPTDFCIGVAGYP
EKHFEAPNMRSDIHFLKKKVEAGADYIVTQMFFDNQQYFDFVNLCRENDINIPIIPGLKP
VSTNKQLTLLPQRFHLNMPNPLVDEVLKCKTNEQVRQVGVEWAIQQTKELIEFGAPCIHF
YTMGKSDNVQKIVGTFS
>A0A5Q2NFC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus pakistanensis|TrEMBL
MGLLEKLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESRVQQFNEAAMTIAKRAAADGGQFVLGTIGGIRGIRKSDATLEEI
LATVEEQATVLLAGNPDGLLLETYYDFEELTATLKMLRAKTKLPIIAQVSMHEPGVLQNG
KSLNSALHELEALGADIVGVNCRLGPYHSIQAFEGVELPEKAFMSAYPNASLLDLEDGRV
VYESETDYFGRAAVALRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVEEKLAKPEKVEI
VREAEPSRFEPLHIKVKRQRSVIVELDTPRHLEIDGFIKGAKKLYEAGADVVMMADNSLA
SPRISNVAMGALLKETHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRQKANFSVAAAFNPNVRVLDRAVSR
LEKKIEHGADYFISQPVYTKEKIVEIYEATKHLEAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSENALARMKACGEDKEHATLEGIAIAKELVEVAAEYFNGIYLITPFLRYDMTLELMKF
IEQLDEQKKGVSING
>A0A6N9SSG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrovum sp|TrEMBL
MNHVHHERVFSFEFFPPKTSEGAEKLRHTRRQLAQLNPTFFSVTYGAGGTTQDRTLETVV
EIQQEGHPAAPHLSCIGATRDSLRQVLAQYRRHGIRHLVALRGDLPSGTLGGGEFRYASD
LVRFVREETGDHFFIEVAAYPEVHPQARSAQEGIRHFREKVEAGADSAITQYFYNPDAYF
SFVEDCDAAGITVPIVPGIMPIANFSQLSRFSEACGAEIPRWIRQKMQGYGDDSASIKAF
GLEVVTHLCDRLLEGGAPGLHFYTMNSAGLTAVIWERLHLT
>S7X1Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella psychrotolerans RS-3|TrEMBL
MKVTDHIKNANGKTLFSFEIIPPKKEIAFSNSIIILSL
>S7VKK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella psychrotolerans RS-3|TrEMBL
MEFKPPFIDVTTSREEYLYIEKDGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGG
FTKEETEYLLVDCHYLGINNVMALRGDAMKHQQYFEACDGGHQFAKGLVSQIQNLNKGHY
LHDVLEADDKSDFCIGVAGYPEKHIESPSLRTDLKRLKEKVDAGADYVVTQMFFDNQKYF
EFVEAAKAEGINVPIIPGIKPIAVKRHLQLLPQVFKIDLPEDLIEAVERCKTNEQVRQVG
VEWAITQSKELQQAGVPVLHYYSMGKSDNVKAIASELF
>A0A1Q4A7G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 65-26|TrEMBL
MNRAVLSGTDGRVDQRLPASIEMLPRHISDLSSLAHRVPTGTRIYIPDLGTDTDDALVAA
ARIVRERGFAAVPHVAARRLSSHGQLVTRICRLATEAGVEDILVIGGSPREPQGPFGSAF
DVLDTGLLVDHGIRRLGVAGHPEGSPDISRDDQALALRRKLDYARQTGSELRIVTQFGFD
GDAFGQWAKTLREDGIDVPVHIGVAGPARFATLVKYAMACGVGNSLDMLRKRGGGLMSLA
RSQSPEMFAEPLERYILQAQTGISHLHVYPFGGIEASIDWLRARGSWV
>A0A2M6ZQW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG07_land_8_20_14_0_80_51_10|TrEMBL
MAKQSFKKALDSGKFVVTAEVGPPKGTNIEEMLHHIDLLKDRVDGINTTDNQSSVMRISS
LAVCRLVREKGGEPILQMTCRDRNRMALESDLLAANVLGINNVLCLTGDYISVGDHVDAK
PVFDLDSVQLIQVVRMMEQGKDLGGNDLDGPVKFCCGAIVTPEADPIEPQLLKFEKKIKA
GIEFVQTQAIYDIDNFKKFMQYARKFDVKILAGIVLLTGAGMAKYMNANVPGIFVPQNLI
GELASAPKGEALKTGIAIAGRMIKQLKDEEICDGVHIMAIGREGLVPDILTAAGL
>A0A3D6CZ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter sp|TrEMBL
MSAPRISFEFFPPQSLDASFRLWETVQALAPMAPNFVSVTYGAGGTTRKVTHEAVSAIHR
NYGLNVAAHLTCVDATRVETLEIAAAYAEAGVTEIVALRGDAPKGATRFTPHADGFANSV
ELVEALAKTGKFKLRVGAYPEPHPDAADSFADVAWLKRKIDAGATSAITQFFFDADTFFR
FRDACVKAGIDAPIIPGILPIQSWDGAKRFAARCGTKVPVKLDEAFTTAARDGRENLLAL
TQCTSLCDRLIQGGVQDLHFYTLNRPNLTREVVRALGIAPEVALEKVA
>A0A223S4U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis gilva YIM 90087|TrEMBL
MRTRRSRTIRKEPRVPNFADLLTSPEPSRPVITAEFPVMDGGGLPEIAAKLACLTPYVDA
VNATDNASAHAHVSNVALAIAIQQYGVEPVLQLVCRDKNRLALEADIMGAALHGITAVSC
MTGDDVTAGDEPEARRVFDLDAVQLIRVAAGLAKGHYLSGRPIDPAPKLLIGAVENPAAP
PHAYRVRRALKKAAAGARFLQLQICYHPDRLAEFTRIGAATGLTPKVALLPSIVLVKGAR
SLRYMNKRVPGIHVPDELIDRLAAAPDQREAAYQLALEQATHALSLEGVRGLHFIDFRHD
DALGRLCSDLGLPTVRSAPEGNALAV
>A0A2K8LA35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariprofundus ferrinatatus|TrEMBL
MKLSEILSSANKPLFSCEFFPPKTDKGEENLWNCLRELQAVNPAYVSVTYGAGGTTQDRT
KGIVTRIKDETGLSPVAHLTCVGATKEQLGELLADYQAAGIQNILALRGDAPEGMDRFEA
VAGGFSHATDLIAFLREQGDFSIACATYPEGHPESKGGVRDDIRYLKMKQDNGADCAITQ
YFFDNEAFFRFRDSCDAAGITMPIIPGIMPIGNFDQIVRFSSMCGATIPAWLHEQMSPIS
DNPDAVAGLGIELAVKQCAELLENGAPGLHIYTLNKSAASIAIHERIRGYL
>A0A3D9HLC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Seonamhaeicola aphaedonensis|TrEMBL
MKVTDHIKEAKGKTLFSFEVIPPKKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYID
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKDEPYFKPVKGGHAYACDLVEQIANLNRGKYLHDDVEVEHYSDFCIGVAGY
PEKHMEAPSLQTDLKRLKQKVDAGADYVVTQMFFDNQKYFEFVEKARNMGITIPIIPGIK
PIAVKRHLQLLPQVFKIDLPQDLIDSVEACKDNQAVRQVGIEFAIQQSKELKEAGVPVLH
YYSMGKSDNIKAIASALF
>K0EIT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas macleodii (strain Balearic Sea AD45)|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGA
>A0A7W5VGM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK591|TrEMBL
MALKNEARGRNIRISFEFFPPKSEEMEGQLWHTVSQLQDWDADFVSVTYGAGGTTKAPTL
STVTRFLSQTPFATASHLTCVGATKEETHQVVDTFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLREIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGANRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGVSRRETKSAGAAA
>A0A0W8G013|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrocarbon metagenome|TrEMBL
MKVIEHLDKAKNTVISFEIIPPKRGGDIKTLLAVLDEIIKYNPPFIDITSHAAEVIYEET
PNGGYKMKVKRKRPGTLGICALIQNKYNVDAVPHVICHGFTREETEDFLIELHYLGIDNV
LAIRGDDNGYHKPIKFGRSVNHYAVDLVKQIVDVNKGKYIEDTLLDAKPMNFCVGVGGYP
EKHFEAPNLAVDIKYTKEKVNAGAEYIVTQMFYDNKNYFNYIEKCKDAGITVPIIPGLKI
VTSKKQLQSVPKHFYIDLPDALTEEIEKAKPEHVVEIGVEWTAKQVEGLLNNNVPAIHFY
IMQDPKPINMLMNKLKL
>A0A7M7H3Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nasonia vitripennis|TrEMBL
MYLRRVCRLASVGRVSRRSLDSSRGMRHRVLGDEEPQVDESESVLASATTLDPGPPVNLA
GLIREKIERRESFCSYELFPTKCHGVYQGRRGRRRDACRFFRDTQICEPLFYALTWHEGW
ATGEERFPSLKSAEVFPRNTLLHCTAKGLKKTDAEMILTRALELGIANIFALQGDSGSDD
GDFDHASDLVKFIRERYGQQFSICVAGYPEMHPHSPSKELDIFYLKAKVDAGADFILTQF
FFESQLFIKFVNDCREVGISVPIIPGIYPFTDVKLLGKMIEICHTNIPDWIQEELRHIED
DDEAVRKFGIDLSVKLIKEIRESAHFCGYHVYTLNRSFSAIEVHRQLNTQHEIDQLVASN
S
>A0A6J4FF42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum sp. LM-5|TrEMBL
MNSPLPIAAASAQPVKVSFEFFPPKTEKMQETLWECVKRLEPLAPAFVSVTYGAGGTTRE
RTHDTVVRIARETSLKPAAHLTCVGHVQGEVDDIARRYWDEGIRHIVALRGDAPEGSGAY
VPTPGGYGYAVDLVRGLKRIADFEISVAAYPEMHPDAPSAAFDLDNLKAKVDAGATRAIS
QYFFDPAVFLRFRERAVAAGITVPIVPGILPVTNFAQVQKFSAACGASVPGWMATLFEGL
DNDPETRRLVAATVAAEQCRALAADGVSDFHFYTLNRADLAYAISHILGVRPR
>A0A852YWP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora biskrensis|TrEMBL
MNTNARQQLQHYLRNARYEVLPLRGALEQAQGLPPGTTVTVTSSPSKGTEATLDLAARLR
GSGMHVVPHLAARLVRDNAHLDELLARIEALGLTEVFVIAGDADDPAGRFTDALSLLRGM
EEIGNRPHRVGITGYPEPHSFISDQMTIQATDEKARYADYIVSQICYDPNTIASWVKTMR
ARGVTLPVYIGAPGSIDPSKLLRISMKIGLGQSMRFLRKQHGVVGKLLTRYTPENVFDEL
SPYLVDPDYNIAGCHLFTFNEITKTRQWAMETADRLQEVPA
>A0A7H2WJ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLESAGINLPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A4C1ZNU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eumeta variegata|TrEMBL
MPSECVKLTDLIKTCTSFSYSVEVTPEIDIEELNNVELQPLFCSITWHAKTHRCKSLDIP
PIKVAQKLKDKGINVLLHVSCDFLRKSYLDALLNKLKDIQICNLFIVLGESFDPATSDFK
NTKELISYIRDRTGDYFCIGVPGFPDYDDEKLKLLKDKVANGVDFILTQAFFESSVFLHY
VERCRDLEINIPILAGVYIFETLQQLRSFIKMCRVKVSECCLDLMKKQHDESESALISVH
DSIICDKQAFKVKLPPFSSLPLTIRVPPNPTTYIFFRVPFHTYFDAFRKFTAQRRTARDD
QLWKTVTVSLNVAEHHVRVPTAGDMSYGRFLKRSPRHRIPTRVGSICPTWYGSGPVEWND
MT
>A0A2A3JZE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yangia mangrovi|TrEMBL
MTRPDISFEFFPPRNIEATFRLWDTVQALSPLGPRFVSVTYGAGGTTRELTRDVVATLHK
NSGLKVAAHLTCVDATREETLAIARQFQEAGVNDIVALRGDPPKGASGFTPHPEGFGSSV
ELIEALRETGDFTIRVGAYPDKHPEAPSATADVEYLKRKFDAGASEALTQFFFEAESFFR
FRDECEKAGIDKPIVPGILPIENWKGARRFAEATGTKIPAWVIEAFEKAERDDRQDLLAT
AMCTELCNELLEGGVDKLHFYTLNRPELTRDVCFALGVTPDNKLENVA
>F9HAW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis SK1073|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISSLQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>C9N1D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia hofstadii F0254|TrEMBL
MKIKDMFEQKERLISFEIFPPNKNFSQEKLKEVTAELVECKPDFISVTYGAGGQTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEIHDYLQEAKSKNVKNILALRGDVPQGETEDIYN
KGDYKYASELISDLRKNSEFDDFSIGGAFYPETHYENNDLVDLFHLKNKVEAGTDFLTSQ
MFFDNDIFIKFKEQAEKLDIKVPLVAGIMPVTNAKQIKRIIELSKCSVPHKLDKLLEKYG
DNPESMKKAGIMYASEQIIELLAYGIKGIHIYTMNKPEIAKEIMKNIEFAR
>A0A522KRY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp|TrEMBL
MKPIELSFEFFPPKTHDGVEKLHATRVQLAALKPKFVSVTFGAGGSTQQGTLDTVIEIAK
DGIEAAPHLSCIGSSKEKLREILEQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQETGDTFHIEVAAYPEYHPQARSPRHDIEAFARKVKAGANSAITQYFFNADAYFRFVD
DVHKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDREAIRAFGLDV
VTDLCRRLTDAGAPGLHFYTLNGAAATKSICERLGL
>A0A167FEB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beauveria brongniartii RCEF 3172|TrEMBL
MERITDKIAALPADGEYFSLEFFPPKTAMGFSNLRDRLHRMEQGLRPLFVNVTWGAGGST
ADKSLELAELCQRELGMTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKDE
YRTTDDDESDSDGAADGQAFVWAIDLVKYIRRKHGDYFCVGVAAYPEGHADESHPLGQSL
AHDLPYLVDKVQAGADFIMTQLFFDIEAYDTFETTLRGHPSGAFQTIPILPGLMPIQSYS
MIKRTAKLSHAAMPPALLDRLNAVKGDDERVKAVGVDILSELVEQVRTVKTKTTPGRPRG
FHFYTLNLEKAVTFILERTRLIPDAPDEEEVVIVDAGPTSAPFLQVNGHAIPPPQRSHSR
SSRRHSSVGSDPHNRVIVGSGSGRRTNPEWEATGAEAAVPAVASQLNARANTLAISEGEG
ALGREATWDDFPNGRFGDSRSPAYGEIDGYGVSLHMSVAQAVRLWGHPASSRDIDDMFVR
HVRGELSALPWSEEELLAESSTITPHLAALNGRGWWTVASQPAVNSVRSTDPTFGWGPAN
GFVFQKAFVEFFLSSADWASLKDRLQAPGVREVVCFYAGNAKGDLVSSDNSGSAAAATAA
ASTNAVTWGVFPSKEIVTPTIIEEVSFRAWCEEAFGIWDEWSRVYAKGSPSATLLSGIRD
DYWLVNVIHHDFVDQQALWDLLLA
>A0A0V8SMD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. B6|TrEMBL
MTLVAEVDAPPPVRAATRRAEQAGALDRPTVSFELFPPRNPDAAPRLWRTVRELESVEPD
FVSVTYGASGRTRETTRALVRRLLRETSLTPIAHLTCVGTSREEVTTIVEEFLDEGVRSF
LALRGDPPAGEPDWRPHPDGVDTAAELVELLREIEGRRCGRSASQAVRARVRPLSVAVAA
FPRGNHATGGTRAQDVQALLAKQEAGADFAISQVFFDAEAYLGLVDEARAAGVTIPIVPG
IIPTTDPARLLRVQELTGVPVPQHLLDLLGGTDDPAERHRRGTRAGVDLVNGVLDGGAPG
VHVYTFNTHEAALDLLDGADLVGGRRTTVTDPAAPPTTAPTTTAAPTGAATTTPRGNLS
>A0A438NFS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala mesophila|TrEMBL
MHISKKLALAHEKKKPTYSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
TLTLEMVNAAQSQYGLETCMHLTCTDMEKTQIDQALEHAFKSGCTNILALRGDPPRDQEK
WEAKEGGFQYAKDLVKYIRSKYGDHFDIGVAGYAEGCDDHRDVDLLVQHLKEKVDAGATF
VVTQMFYDVDIFLQWTQKCRDSGINVPIIPGIMPISTYASFKRRADWTKCNVPPSWSEAL
DPVKNDDSAVREVGKDLVAAMCQKLLDAGILHLHFYTMNLAQSTRMILDELSLTPSMSGT
PLEKPLPWRQSLGLNRRDETVRPIFWRNRNTSYVARTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANIKLWGRPKSLRDVTVLFTKFVDGSLDRLPWSEGAISAEANSIKSDLL
KLNKHGLLTINSQPAIDGVSSSDPVHGWGPAGGWVYQKAYLELLAFPSIIDKVIERLEAH
PNLTYYAVNQKGRLLTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WSKCYAPGSGSRKLIETIMDECYLINIVNNNFRETHEIFKIFEGLEPQDIDKVFEDEVVD
VTNNAKEPVNGQASSDAVKGNAVNGDGPKVSSQLNGVTA
>A0A1T5BTF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parapedobacter luteus|TrEMBL
MKITEHIKNAKGKTLFSFEILPPVKGQSIQSIFNAIDPLMEFNPPFIDVTYLREDYIYKQ
HPNGLLEKVAYRKRPSTVATCAAIINKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARKSDSSFIPTPGGHAYASDLLQHVVNMNNGRYLHEDMENSERTDFCIGVAGY
PEKHFESPNLDTDFKYLKMKVDLGADFIVTQMFFDNSKYKAFVDRCRANGIHIPIIPGLK
PLTGSKQLVSLPKTFHLDIPLELSEAVQACRSEQEVRDVGIEWMIHQCKELIAMGAPVLH
FYTMGNPNPTKRIIQAVF
>A0A6P5V4M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila obscura|TrEMBL
MHAIETSSSSGLEPTSYVPCVRYTSGQNGTDLAEQRVGALVTELTARRQFFYGIEVVVLQ
GGKPTCLDFNSFLPVLPTFVSIVWLGLAYCHVNPIDQVKSLQLARSLESRIPVMPHISAY
CLSQERLDQFLALNFTNVLPIRGDAVHETQNFQYSWQVVDYLRRQRGENISICVAGYPEG
YTSLPERQDPVQAMKFLKKKIAAGADCIITQMCYRSATIIQFIRDCRSAGITVPIVVGQT
VADCFRTYRMSENIAGVHLPPDQRAELLQLKSHPQRVTQFFVQLSIRIIRDILDADLGVY
GIQFYTFNKFEPVYEVLKELRSLDILKDADGH
>A0A8H5CAX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tulosesus angulatus|TrEMBL
MRISQKIEQSAKDGKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPREKVDIALRDAKESGCRNILALRGDPPMGKEE
WEAVDDGFVHGIDLVRHIRKHYGDYFDIAVAGFPQHMNLPDAERDQEIQWLKEKVDAGVN
FIFTQMFYDVDLFISWVKAVRAAGITIPIVPGINPIQTWNGFIRATSLSQTVIPQALMDI
LEPVKNDDEKVRELGIKIVADLCRKILDSGLGIKGLHFYTMNLERGTKMLLEELNLVPRI
ETIKPLPWRQSLTPTRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKENALQLWGTPTSIEDVSSLFSKFCTGDLSALPWCDQAPSMETSVIAQQLA
KMNALGFLTINSQPAVNGARSDDKTFGWGPSNGYVYQKAYLEFFVHPELLQLLLKQIERD
NNITYYVINKRGDLQTNTHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAFELGSQ
WAKLYESDSPAHKLIDEIMETYSLVNVVQNDFHNTDAIFEPFWKAGAEWEALKAKSANGS
AHGANGKPVVNGVNGA
>A0A8I0KI34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium tamlense|TrEMBL
MPASPDAASHDPILQALASDRPAVSFEFFPPKDDEGEAQLWRTIDDLSPLEPTFVSVTYG
AGGTSQDRTVRITERIAREASMPPVGHLTLVGQSRGEIETVLKQYVAAGVQHVLALRGDP
AGGPRAPWEPHPDGMSHAIELVDLVREVGGLSVGVAAFPEGHPDCGGLDEDADVLVAKSR
AGASFAISQLFFRADDYFGLVRRVRDRGCDLPIVPGIMPILNFGQVARMAELSGADMPRE
VLDQIEPIADDRAAVRAKGIELATQLCRDLLAGGAPGLHFMTLNRSPATREIFEQLRADG
LV
>A0A731YUX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar London|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGRGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6I9YS51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thamnophis sirtalis|TrEMBL
MCRELLDSGMVHGLHFYTLNREVATMEILRRLGLWKEDPRRPLPWAVSAHPKRRVEDVRP
IFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEE
LTSEESVYEVFRCYIAGEANRNGHKVTCLPWNDDPLASETNLMKDELVKVNRRGILTINS
QPNINGKPSTDPIVGWGPEGGYVFQKAYLEFFTSTENIKALLTVLKKYGQRVNYHIVNVK
GENVTNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEEESP
SRMIVQYIHDNYYLVNLVDNDFPLESCLWQVLEDTYEQLNGPGEEVKSSGS
>A0A6A8HMS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ligilactobacillus ruminis|TrEMBL
MSQTTFSFEIFPPNKESAAEKLTETLDELVGLSPDFISVTCTNKNDDLARLTVKLAGYVK
NRLDVPSIAHLPAAYLDKQQVSEILNELETLGVTNLLALRGDRIEGRKPKDDFRHASDLI
AYVHENFPEFHISAACYPEIHPESDSRVDDIKHLKYKTDQGVDSLITQMFFDNESFYGFK
ECCELADINAPIVAGIMPIVRRNQALRILKTSSATLPKKFTAILNKYRDDPESLKAAGLA
YAIDQIVDLVTQGVAGIHLYTMNDAETAKYIWQATRSLFENGRKVHQV
>A0A1N6XF30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella morhuae|TrEMBL
MAFHHAQHSQSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLKPKFVSVTY
GANSGVRDRTHSVIERIQQETNLVAAPHLTLVDASDEELLELAKHYWKSGVRDIVALRGD
LPAGSAKPTRFAADLVRLLRSVADFDISVAAYPEVHPDANNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPGWLHKQFE
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRV
>A0A8H3ABN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKLSEKLANHTSDAPYFTFEFFPPRTDQGYSNLLTRISGLASLKPIAASVTWGAGGSTRD
RSLDLAGFCQRDNGLDIILHLTCTNMEKGTIDDTLATAMERGISTVLALRGDPPRGEEYW
IPADPRFQHAEDLVTYIKQHPTFGSHFCIGVAGYPDGHSEGGGEEEQLSHLKRKVDAGAE
FIITQLFYDVEKFKSWVRKVRNTGISIPVIPGVMPLQTYATFTRMTELCKATVPQHIQAN
LDAIKHDDQLVKEYGVSLAVSMIRSILVDGDIKGVHFCTLNLEKSVRKILDELGWTHESL
HYNQIITDASQSPRIRPAAADALHHPVAFTISPSEATQHAATSLTEHSRTGTLRTAAEAI
DSGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPPHVAVSQWGRPTTEQDLSDLFLAYLN
DKTSTTPFSPEPLSDESTPILPHLVSLTKRGLWTVSSQPAVDGALSSDPVVGWGPRDGRV
FQKSFVEFFATEADLNKVAKAVEDSGEGWVTFFAGNNDDGFLTNIPDSGSNAVTWGVFPG
QEIAQPTIIDRDSFLAWKDDAFMIWHDFGLCYPPDSPTRKLLEGITKTRWLVSIIHHDYK
DSNALWDFLAKHLD
>A0A242LF34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus sp. 7D2_DIV0200|TrEMBL
MRTDTLFKEKTVFSYEIFPPRRTAPIDTIYHTLDRLKGQQPDFISVTLGAGGTAANLSTA
DIAQKIQDEQFLPSVAHLPAVNFSKDEIVVILEELKQKKVENILALRGDLLPDREPKKDF
CYANDLVSFIQEQGAFNIIGACYPETHGDSENSVTDIRNLKRKVDAGTNQLITQLFFDNN
YFYTFKEKCDIAAIEVPIQAGIMPVVNKKQIERMVKMSNVTLPTKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVAQGADGIHLYTMNNPYVAQKIREATRSLFDA
>A0A0Q7Z7T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root151|TrEMBL
MDQQSPRGIGQLIREGERSFSFEFFPPKDEAGEAQLWQAIRELEPYRPTFVSVTYGAGGT
TRDTTVAITARIARETSMVPMAHLTCVGHTVDELREVLKSLTESGVRNVLALRGDPPGGP
GTAWEATEGGVNYASELISVIKEIADVSVGVAAFPEGHVDAASLDDDVAVLRAKQDAGAE
FAVTEMVLRAADYFGLVERARATGVEIPIIPGVMPILNINSMRRMVELSRRELPTEVVDR
LRPFEEDPAGLRAEGIRIATELCEAMLDGGAPGLHFYTLNRSKATREIFEGLRITV
>A0A1B9JJS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNQKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKTEMKKILHDLKCAGIDNVLALRGDINPNVKPKDDF
RFASELVSFIKENGDFNVIGACYPEGHLEAATIKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKARDMGIDVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKSI
>A0A1I2SXG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium spheniscorum|TrEMBL
MTTALLYRPDTAPDYPTVSFELYPPRSLEPASSVWVGVNRLIGAAPDYVSVTYGAAGNRA
DSRDRSVQVLLKVLKEHPHLPAVAHLTCLGSTRGELQMIVRLLLHAGIRDFLALRGDMPP
GGIDHIAPEHRLNRGVELVQLIREIAAEVCPEEVVSIAVAAYPATRGQARSNDIAALVEK
AQAGADYAITQVFYDPEDYASMVRELRLAGCRMPLVPGILPLNDLRRLQALEKLAGVKVP
EHLRTMLSQKDPRTRVADSLKATLDLISGVLDAGAPGVHIYSFNRPRPTLDLLEYLRAAG
YLARKPRAENAQRQRPQRGPVDAELVGLALRHLTPAS
>A0A1F8R7A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_60_22|TrEMBL
MKAGTNLEKILESGKFAVTAEAGPPKGTSAAVIQRKAEMLRHCCDAVNITDNQTAIVRMS
SLAGCVIARQAGVEPVMQMVVRDRNRLALQADILGAIALGVGNFLCLSGDHQKFGNHPQA
KGVFDIDSIQLIQMMKQMRDEKKFLNGDEISGDVPMYIGAAANPFADPFEYRVKRLAKKV
KAGVDFIQTQAVYDVPRFARYMKMACDMGLDKKVHVLAGVIPIRSLGMARYMRDYVSGVT
VPDEIITRLEKAEKAKEEGVKIILDIIEQLKEIPGVHGIHIMAVGWEDIVQEMVEKAGLM
PRPVL
>A0A3L8A2I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium J10(2018)|TrEMBL
MKITDFIAANGRTGFSFEVLPPLKGRGIAQLFRNIDSLKEFNPLYINITTHRSEMVYKNT
PDGLYQKVSERSRPGTVAVAAAIQQKYGIPAVPHIICSGFSKIETEYALIDLNFLGITNL
LILRGDKAKHDNRFIPNDNGYAHASELQMQVNEFNRGYFIDGTKMDIVTGEQFSYGVAGY
PEKHEEAPNPDIDLQYLKHKVDNGAEYIVTQMFFDNEKYYNFVDRCRRAGINVPVIPGLK
PITTKSQLTLLPKVFHVDLPMELAKELIACENDAQAKEIGIEWCKGQAADLIAHNVPSIH
FYSLNATKSVETVARAVY
>S3K2R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa SPC777|TrEMBL
MTTRLQRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPVHN
>A0A6N3R2D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella flexneri CCH060|TrEMBL
MSFFHASQRDALNQRLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7V4T7X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MTSLFLNNDEFTITIEVVPPTGNDPATILKKLTSISDLSFHGFSVASNPVAKPKMSAMVF
THLIQKATQKPAILHCTVRDHNRLGLQSELWGAKALGIDTVISVTGDPSAFRAEEPTSTV
GDLNVCQLISMARDSDLFTGAVLDFRPEFNGLEHETKRLAKKVASGCRFIVTQPIYDEET
AKEIHEAVKHLNVPVIMGILPLLSYKHAVFLHDKVAGIAVPEPLRKRMEEAQYPAKEGVS
QARQMLELAKKMFSGACIMPPFDRFEILPDILKS
>A0A7Y3AE92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MEVTNTSYSPRSTHLIAEIDPPKGTNLEPFLTSALSIRGRIETIRITDGEHAIMRMSPLA
PSLFLKEKGFEPSMVINGRDRNRISFQADLLCASALGIKEIVIKEGHDPKEGDQPVARTS
GDLDLATMLQCAAALNNGTDLGGEPLDGATDFNVGVYLELSDDVNFNRERAEYFKQLEQH
GVQSVTLSPTYDLNIIEQFLPFAEETGIKLYTSLLYLKSVTMIRYLNNLTGIPSIPQEFL
KKMMQAPDKKNAGMHVAVDFLEELAPLGDGVVLLALGWKEKLPEFLDLIGR
>A0A7Y3DP73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MPTPFKEALKSGKFVVTSEVAPPKGTNLEKFKHHIELLKDKVDAMNVTDHQSSVMRYPSL
GGCLMVKELGGEVILQMTCRDRNRLALQADLLFASSRGIDNVLCLTGDSVMLGDHKDAKS
VFDMDSSQLLEAVRILEGGKDLGGNELDGGVSFCAGAIVTPEADPLEPQLIKFEKKIDAG
AEFIQTQAVYDLDKFEEFMSYARKFNVKILAGIILLTSAPMARFMTKNIAGVFVPQNLID
EMASAPKGQAISKGIEIAGRMIKRIHEEKMCDGVHIMAIGKEELVPDIMAAAGLS
>A0A1K1Q826|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. UNCCL117|TrEMBL
MKPDLREALRRGVLVGDGAMGTYLYQMGFPVGISYEELNLLKPDVIRDVHRRYYEAGARL
IETNTFSANREKLSKFGLEGEVEAINRAGVALARQAVGDDAYVVGAVGSIRAGKRKNVRT
AKIKEDLRQQIEVLIDAGVDGLLLETFFDLEEMLLVLKLIRKLSPLPVICQFATEGAGAT
MDGVPLKEAFERLLAAGADVVGFNCRSGPNGLLRSLEHVSGLADSPPMSVFPNAGLADYV
DGRYTFAATPQYFGETARRFVDQGARIVGGCCGTTPEHIAAIAASLADYVPQPHAAADKK
TPAGGAEQPAALAALTSSAAALKPVQPNIVDLVKERVTVIVELDPPRDLDIAKFMAGAAA
LKAVGADALTMADNSLAVTRMSNMALGSLVQEQVGIRPLIHIACRDRNMIGTQSHMMGLH
ALDIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKALKKRAGFVV
GAAFNPNVKHLDKAVQRLERKIEAGADYIMTQPVYDAELIERIREQTRHLDVPIFIGIAP
LASGGNAEFLHNEVPGVQLSDEVRRRMSGLKGEEGRAMGVQIARELLDVALRHFNGIYLM
TPFMAYEMTVELTRYVWEKSGRSVSHLSPLAK
>C7JBE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter pasteurianus (strain NBRC 105184 / IFO 3283-01)|TrEMBL
MSLSRLSVELIPRSAEALAADVATVKAAFPAADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQPGLEEILVVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMQGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLDANIQFAQTVLKELAQEKGKAYLMPVRIKLEQY
LPALLDAVA
>A0A6N9EIA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. SB0675_bin_7|TrEMBL
MKSQVGPSAFQQALASGQPVITAEISPPRGGSVQHVLTTADRLRGRVHALNVTDGSRAVM
GMSSVAVCRLLLERNLEPVLQMGCRDRNRIALQADLLGAHALGLRNVLCLTGDPVKAGDQ
PKARPVFDYEAVRLLQDVKSLNRGLDALGRPLPDGPTALFPGCAADPQSPSWSGLKSRLQ
RKKEAGARFIQTQMVTDLAALRRFCRELAAPLGLPVLAGVFLLKSGKNARFINRMVPGAS
IPDAAIARLDAARTPRAEGLRMAAEQVAAVLEIAQGVHLMAIKAESAIPQILDLAGVPPL
APPMVDSVGPRSLAVEPR
>A0A7Y3DTV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKLKDALKKKKFVVTSEVQSPIDREPEDLVRSLASVSGRVDGVSLSEVELEGFVGDTIRT
CELLNKSQLEPIYQTTTRDKNRLQLQNDLVEAHNSGIDNLLVFTEDYRITGDSLQEMMFF
HVDAGKLKSVLEHMREGRTVEGDSLKSKADFLLGSGVESSWGKSVPDLEMKEMEEMTKLG
TSYFLTTPIFDVDQFEKFLKQTQTFGVPVIAEVMILRTVGMARFLNRHLKSGMVPDWIIQ
KLAREPDKQKASIEIFTDIVTGLKDLCQGVHIITIGGEEKLKLYLDSAKLK
>A0A2U3KGX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfosporosinus infrequens|TrEMBL
MENKFKDSILDKNVLSVTWELVPGRGANEKAQQSAMASSEQAAKGGRVHALTITDNPGGN
PAMLADYLGVEILGMGIEPLVHFTCKDKNRNQMESQLYALDRAKVRNLLVMTGDYTYSGF
QGRPKPVFDLDPCNALKLISDMNKGLEIPGMKGPTYHAPSDFFAGAAFSPFKATEAELMG
QYYKLKKKIEGGAKFIVCQLGYDARKFHEVIQFLKFNKLDIPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNTEKSAADKGAGVRMLRAAKLYAILKGIGCAGVHIGGHNLKYEQ
VEYILDEGEKLYPKWQELVKEFDYPQPDGFYLYEKDEKTGLNTDKLTNRKQRPLDAPAGA
GYSFMRGMHALLFTPNKKLFGMMRGIYNSAEGKPRLKRMHTLEHIAKVVMLDCKDCGDCA
MLDLAYLCPMSQCPKNQRNGPCGGSFNGWCEIYPNEKKCFWVRAYARLKKFGEEGSLDVP
MVPPANWDFYQTSSWSNFYLGKDHSAPVLGIKRPPSKVPASK
>A0A3M5Z9C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. coronafaciens|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDGKDDLRNLLAQYREAGIKRIVALRGDLPSGMGMASGELRHANDL
VTFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A3S1T9R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.13.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A249M212|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CLI2509|TrEMBL
MASGTASTWTSEHPTVAEVLASGKRSYSFEFWAPKTPKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRTGTVRATQAIAENTTLVPVAHLTAVEHSVAELRHMIGQYADGGVRNILAVR
GDPPGDPLGDWVAREDGLTYAAELVRLIKESGNFCVGVAAFPDMHPRSENWDSDVRYFVD
KCRAGADYAITQMFFDPASYLRLRDRLSAAGCETPVIPEVMPVTSVRQLERLSRLSTAVF
PETVKERMLAAKDDPAAVRSLGIEFATEFCARLLAEDVPGLHFITLNNSTATLEIHENLG
LPHHRP
>A0A1F3ZKE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_62_17|TrEMBL
MSTAQQPAATQLQQALRSGAFVVTTEVSPPVAADVADFIAKAMPLKGLATAVNVTDGAGA
KTHLSSLVAAHFMLQNGIEPILQMTCRDRNRLALQADLLGAMALGIRNLLLLSGDSPKLG
DQPDTKAAGDLDSKGLLAIAQRMRIEHRLPPGTEIKGNTALVLGAADVPIDPPPDWNPAS
LRAKIEAGADFVQTQFCMDMDIARRYAARLLDLGIAQRLPVLIGVCPIPSGKSARWMKEK
LFGTIIPDAIIARLDAAADAREEGKKICVELLRELAAIPGIAGAHIMAPVNPSVVPEVIA
GARVTALRRAPV
>A0A8E0GFJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia thailandensis MSMB43|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVE
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDKDSIRAFGADV
VTGLCRRLVDAGVPGLHFYTLNGAAATKIVCERLGL
>A0A7C2PT22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MRIRELLATGRPCISFEFFPPRDEAGFRQLGDTIASLRELKPTYVSVTYGAGGSTRRQTV
ELVTHIRRDHGIEAMAHLTCVAAARDEIRQVLQRLQDAGVENVLALRGDPPRGSATFEPH
PAGFRYACELAAFAKAGFRFCLGGACYPEKHPEAPSMEADLDALRRKVDAGVEFLITQLF
FDNRLYFDFVSRLRSLGIGVPVLPGIMPITNLAQVERFTKMCGASLPEPLLKELRRLQDD
PHDVLALGVAHATAQCLELLQRGAPGIHFYTLNRSHATRTILQAIRNVYPPARTPAGTF
>A0A7C5ZHI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MKFPQHYATGSPVISVEIGPPKTDQEYAELERRLPALAGLAAPLFHVAYAARPSSRRFAL
ELAGKLREVYGKDVASHVTCVAATAADIDALLDELARIGVENVVALRGKPPRGHSQFLAP
PGGFAHAEQLVAHIRRRGGFSIGVAGHVEKHPESPNAASDLEHLKNKIRAGADVIFTQFF
YDNQVFYRFVEQCRAGGIDLPIVPSLLPILDAAQGLALAEAFGVSVPPALRTDLQVAHKD
PTLVRRIGIEHAIRQARDLLAHGVCGIHFHSLNQPEPMMQILWRLTTPGA
>A0A7S4PGJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paramoeba aestuarina|TrEMBL
FFSFVSFLFFFFFPLLSQLFPFYFPSLNLPFLKFKTRNMSSCDVQEFNKVTSEQKEFISL
LDSGNPFMLDGAMGTSLYSRGYFINRAFDEANCTCPDKVFAVHEEHIASGADVIETNTFS
ANRCMLSKYGAADQLEAINRQGVKIARKAINESRRQVFLAGSIGPTGEAIGYMNDSTVET
ITKAFEEQIHILIDEGCDLLIFETFRHLQEMKICLKVARKCFPGGIIAQMSFEENGNLAD
GTPPCRVAELLHEWGANAVGPNCDGPAAIYDIAVKMVCKKVAPVVACPNAGHPRLLDSRM
LYMATPEYFCVYGKRMLKAGVRGVGGCCGTTGDHLEMLTGSIRMLAAGVDHGELSDDAPD
SPKRTERGCAGSVVANINKCEKTLEPVPASERSNFGAKVMRVWEERLKGGTQRKAPTSRE
DFVVSVEVNPAPGLDVTKRVEEARKLKAAGVDVINIADGPRAAVRVSNTALGLAMQRELG
TEVILHVCCRDRNLLGLQSDILGYHVLGLTNLVIITGDPPKMGDYPKATAVFDLDSVSLL
QLINGLNRGVDPAGKVSSGQTRFFLATGAEPGAVDYERELKRLRQKVAAGAQLIMTQPVY
DIAVANKFLDDIQDLHVPVLLGLCPLVSARNAEFLHNEVPGMQIPDPIRERMKKAGRGPE
AVAEGVKIAKEMLNGLQDRVVGCYIMPQLGKFAAAIDILADLGYGAPVENGDAKKENGLC
>A0A3R6NIC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF34-10BH|TrEMBL
MGNTKHTKEQIRERIQQKKILFDGAFGTYYGGKYDTKQLPELANLEAPERVREIHTEYLE
AGAQILRTNTFAANSFCMDRSKEQIEETLRSGVRLAREAVAAWRERTGETKEVYIAGDIG
QIPGDALAQKDTLCREYKEICRIFLEEGADFFVFETFSEMEELLPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGEAKEIDAVGFNCGVGPSHMHRILQILEKPEGKLLTALP
NAGYPQMVTGRMIFTGDNKDYFVDRMQQMTALGVDMAGGCCGTTPEYIAELAGKLDLTQY
PQAKKDTEPEKKQAPKEDRSFYHTKEAEGRNRKLIAVELAPPMGIDDEKLMDAAHLLQKS
GVDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGI
QNFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFTQAPASYGGAINQGRRNL
EVEIGRVKKKMAAGATFFLTQPISTQESADRVRRIKEETGARILCGIMPFVSLKNATFMK
NEMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVIVMTEDFADGYYFSFPFNRVTMLE
KILN
>A0A2D6LMU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MSQTSPPTRVPRFEPWYKPTLRQRLSQTGAFVTCVELVTSRGIITERSSRRVLELARRLA
EHPRIDALSITDNPGGNAMLGADTLGTDLIARGQEVIIHLSCKDWNRNALQSRGWELASG
GFENVLCLSGDCPTSGYEGQAPGVFDIDSVALLKMFTDMNAGLEMPLRNGGRSKPMQHTS
FLKGAVVNNFKLRENEVMPQYFKLAKKIDTGADFVINQLGYDARKQDELMKYMRHKGLDV
PVLYNVYVLSGPASRFFNSVKIPGCLVTDELFEVCQKHAQSLDKGKAFFLEFAAKQVAIG
KGLGYRGAYIGGHIQFDDYMRILDLAESFGEDDWVQFAKEIRYDRDNEFHYFEIDPDTGL
SSDVINQRYLASKTPSGKKRQRGFVPLTYKMNRVVHDRVFERDSAGYNVGRRVYDKLDGA
SAKVRRVAHKLENAVKMFGFDCRDCGDCSLPDIAYLCPESQCAKNQRNGPCGGTRDGKCE
VGEKDCIWARAYDRLKAYGEEEQMLDGKVIIKDAALQGTSAWANTFLGRDHHAGNEEKPE
DSNAQ
>A0A1E7NM01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRMDENIKNLHAILDDLGQLSPNFISVTFGAGGSVNSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYNNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELRA
>A0A7V2FZP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MRISALLASGKPTFSFEFFPPKDDAGFEQLYKTIASLKTLSPSFVSVTYGAGGSTRRKTV
DLVARIKNESGIEAMAHLTCVGATREELAGVLDELAAAGIENVLALRGDPPAGSDRFVPT
EGGFAHANQLVEFVRRGHAFCLGVAGYPEGHPETPDRTTDLGNLKRKVDAGADFVITQLF
FDNDDFLRFREAAVRAGIGVPIIAGIMPVLSVAQIKRFTTMCGARIPRDLLRRIEAVEDD
PEAVRHIGMYHATKQCEELLAEQVAGIHFYTLNRSTATRAICQYLLAEREG
>R9RAP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. animalis 4_8|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSLEKPDYISVTYGAGGNTKGRTV
EIADRIKRQNGLESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEKGD
FNYARELIEYIHKKKGDKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRHE
>A0A2G5LPW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 2822-15|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITQMCEQLLQGGAPGLHFYTLNQTEPSLAIWNNLKLPR
>A0A1E5T0D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivirga misakiensis|TrEMBL
MKVTDHIKKAKGETLFSFEILPPKKGESVQSIFNAIDPLMEFKPPFIDVTYHREEYVYKD
RGNDLLEKVSTRKRPGTVGICAAIINKYGVDAVPHIICGGFSKEETENALIDLDFLGIDN
VLVLRGDAIKSEGRFVPEPNGHSYASELLRQVTNLNNGEYLHEEVKQNETDFCVGVAGYP
EKHFEAPSLKSDLKYLKQKVDMGAEYIVTQMFFDNQKYFDFVEKCKNAGIDVPIIPGLKP
ITALKQMSVLPSVFHVDLPDDLVDALDDCKDNQSAREVGIEWAIQQSKELKAAGVPCLHY
YTMSKSQVTKRIAEALF
>A0A4R0BP60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae|TrEMBL
MALKNEARGRNDIRVSFEFFPPKSEEMEGQLWHAVSQLQDRDPDFVSVTYGAGGTTKAPT
LSTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQ
PHPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQ
FFFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFD
DKPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGFSRRQTKNAGAA
A
>A0A259NLY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halothiobacillus sp. 15-55-196|TrEMBL
MGSEAIMHTPLSCEFFPPKSDEGALKLRAVTEQLTAALKPEYFSVTYGAGGSTQDRSFAT
VQAIQTESGVPAAPHLSCIGSTRASIAAILDQYRALGIKRIVALRGDLPSGMRDPGDFRY
ASELVAFIREHSGDWFHIEVAAYPEFHPQSANARADLLHFKQKVEAGADGAITQYFYSIE
AYARFLDDCEKLQVTIPIVPGIMPISNYTQLARFSDACGADLPRWLRKRLEAFGDDMDGL
RAFGHDVVTRLTADLVQAGAPGLHFYTMNQAAPVINICRDAGLMSC
>A0A1Q3JVA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrobacter sp. 62-13|TrEMBL
MIDPSTPVHDAIAAQKRPTISFEFFPPKTEEMERNLWDTVTRLAPLDPSFVSVTYGAGGS
TRERTHSTIARILSETELRPAAHLTCVGAPRGEIDEIVSRYRDIGVRHIVALRGDPPGGI
GTAYSTHPEGYRSSTDLVAGIKRQHGDIEISVSAYPEKHPESPDIDADIDVLKAKIDAGA
TRAITQVFFDNDLYLRYVDRVRARGIDIPIVPGIMPMHNFRQARNFVTKAGTTVPSWLAE
KFEGLDDDPETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAICHLLGIRPDAT
RKAA
>A0A2G8QWU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceibacterium antarcticum|TrEMBL
MTRPEISFEFFPPKNIEATFRLWDTVQVLAPLAPRFVSVTYGAGGTTRDLTRDVVSTLHK
HSGLRTAAHLTCVDATRAETLQIARDFAAAGVTDIVALRGDPPKGANGFVPHPEGFHSSV
ELIEALKETGDFTIRVGAYPDKHPEAPSATADVDYLKRKLDAGADEALTQFFFEAETFFR
FRDACVKAGIDKPIVPGIFPVENWKGARRFAEGCGTHIPDWVIDAFETATRDGSQDLLAT
AMCTELCSELIEGGVDKLHFYTLNRPELTRDVCFALGVTPEAKLENVA
>A0A4V0XM91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHLVDVLARDSFTASFEFFPPKNEAGWDSLFTTITDFGKLRPSFVSVTYGAGGSTRQFTH
DLVVRIGKEAGLDAMPHLTCVNHSAQDIDQILSRYAEAGVSNILALRGDLPSATTALTSA
YSYATELVQAVRAFAQSGRHPDPRGFGIAVAGYPEGHPQTPNTLVQMDHLKAKCDAGADL
IISQLFFDNHAFYDWRERCELAGIKTPILAGIMPITTVTGLKRMAELAGGTTFPAALLRA
VRRAQDDADAVSRVGIHWATEQCRDLLDHGVRGIHFYTLNRSDATRKIYENLGVSSTDAL
RL
>A0A084QU99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stachybotrys chlorohalonata (strain IBT 40285)|TrEMBL
MDKITDKIAALPAGGSYFSLEFFPPKTAMGFSNLRVRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQRELSMTTCLHLTCTNMSPRLIDKALEDAKALGIRNILALRGDPPRNDE
YRDPDEDLDDGRERFTWAVDLVKYIRETHGDYFCIGVAAYPEGHAEENHPLGQSLEHDLP
YLVDKVQAGADFIMTQLFFDIEAYDKFEKVLREHPSGAFKTMPIIPGLMPIQSYQMIKRT
TKLSHAKVPESIMARLDAVKGDDEKVKEVGVDILSELVEQIKEVKSRSPGPQGFHFYTLN
LEKAVSFILERSNLIPDPADNEEALVDDETAGPRITVNGSEPPSKHTHSRTSRRHSSVGS
DPHDRVIVESRNPAHPEWEVSGQEAGIPAGGINSRANTLAISEGEGALGREATWDDFPNG
RFGDARSPAYGEIDGYGVSLHMSVTQATRIWGYPETPQDINQLFVKHIRGELTAIPWSEE
ELLAESSSIKPHLTNLNSKGWWTVASQPAVNGLPSSDQTFGWGPGNGFVFQKAFVEFFLP
SAEWAALQEKLRSPDVKDHVCFYAANAAGAFVSSDAGGDAGGDHAESSTNAVTWGVFPGK
EIVTPTIIEEVSFRAWAEEAFGIWGEWAKVYRRDSGSEKLLNGIKADYWLVNVIHHDFIE
KDALWDLLMQ
>A0A5T0I721|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
VLAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A2E0J7R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor sp|TrEMBL
MMPRPPQIDENPDGVDLPLEPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANAQDVFER
AAIFDGWVDGINAVDASGANCHMSSMGICALLTRMGYATIMQIACRDRNRIAIQGDVLGA
AAMGVGNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDEEKFLSGRTLTTPPAV
FLGAAINPFAPPFDFRPHRLAKKIAAGAQFVQSQYCYDVPMLRDYMKRVRDMGLDEKCFI
LVGVGPLASAKTARWIRSNVPGVHIPDAVITRLEGAEKQKEEGKRLCIDIINEVKEIEGV
SGIHVMAYRQEEFVAEIVHDSGVLKGRKPWKREPGADDAMVAERLDHILHDNPSETPVDM
VKDASEASSE
>Q4W2U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium 179|TrEMBL
MTDLNVIESASKAPDLLATDFSIELSPEMVQKFDPDPTSLPPGSKVFLTHITGKNPQTQI
DAAKQLLSMGYVPVVHMGARNFESDEEFVRLVQAHSDNGVTHGLFLGGNPLKHNGPLHEA
MDLLTHDVLPDTCMTHAFIGGYPEGHPDIDTAQLENARKQKLEACNAIGLKPEIISQFAF
DGDTMAAWATKMSQEEPDVPIRLGLAGVTSLHKLIKFAVMCGVGPSIAVLKKNAGGLMKV
MSDRDPGDIVEKIEHRYFGENSLNVHFFPFGGWKKTLDWVSIKRGD
>A0A844TFD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium cajani|TrEMBL
MSGAMTDLSTSAQANGQDGHLAAKRPAISFEFFPPKTEEMERNLWDTINRLAPLDPKFVS
VTYGAGGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGL
RGDPVGGIGTPYCSHPDGYQSSADLVAGIKKRHSDIEVSVSAYPEKHPEARDFDADIDTL
KAKVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGT
TVPDWFAAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHL
LGIRAKSAQKAA
>A0A060VZI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
MVNNVQRVDDTWRTCTKSNSSGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSNKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGGRATSSRVTLHIGTGLR
AVFIFS
>A0A8C7NZB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
MVNLVQRVEDTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRHRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIR
NYGIEQAVSMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVN
RRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEDT
>A0A1J4YTS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG1_02_37_114|TrEMBL
MKLKDLFKSGKFAVTSEIGPPKGCHIDNVLHEAETFLKGRVAAINVTDNQSSVMRFGSLA
TCHLLKDRGMEPVFQVVCRDRNRIALQSDILSAAGLGIENLLLLTGDHTKLGDHPGAKPV
FDLDAVSLIHTVKKLEQGEDLAGNKLEGEPPKFCIGAVVSPGSEPLDPQLFKMEKKIKAG
AEFFQTQLVFEVDKFVKFMEIVTQKFGKDIPVMAGITILKSVGMAKFMNANVAGVFVPDN
LIEELKKDKEKTKSGETGIEIAVRLVKGLKPYCHGIHIMPLGWDSKVPEILSQAGL
>A0A3D4ZN81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKVIDLIQAEKPCLSFEVFPPKTSDNYQSIQTATENIAALSPDFISVTYGAGGGTSDYTV
SISANLQEKYHVPTLAHLSCISSSHEGVQKQLAAMRAAGIENVLALRGDIAPNAPAAPNW
YYHYASELVREIKSYGGFCIGGACYPESHPESKSQAEDIAHLKEKVDAGCEFLTTQMFFD
NNIYYNFLYKVREAGITVPVVAGIMPVTNVKQIKRIVELSGTALPQRFRYLLDRFGSNPA
AMKQAGIIYASEQIIDLLANDVPAIHVYSMNNVSVAAQIQSNLSEILK
>A0A4S9SD18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSIANS
APQNRVVIDKTSRSASGGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVE
FFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLL
EA
>A0A2H5YNP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR25|TrEMBL
MDSTRIPDPPVAAQPSTLREKLASGRFIVSVEIDPPHGLSPRRALQAAALMKEAGADVIN
VGDSPTAHVRMSPWALCLLIQRELGMETVMHYTTRDRNAMAIHSDMVGCHALGIRNVLCL
RGDPPSLGGYRDVIGVWDVSAVGLIRTLRLLNEGLDWTGRSIGRPASFYIGASCNPNADP
LEPEIRLMRRKVEAGADFFLTQNVFDISRLERFLERASRFGKPIVVGVIPLHSYEHAERL
HHEVPGMLIPEEMRERLRRAGPDAPQEGRAIARDIISFCAGRTAGVYLVPTHGNYNLVAE
LVAEARR
>A0A5M6ZP05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalicaulis satelles|TrEMBL
MSAHATLRPGAPHVSFEFFPPKNEAMEARLWDSINRLQPLGPAFVSVTYGAGGSTRERTH
RTVKRIVEETDLLPAAHLTCVSATRAEIDDVIRSYWDAGVRHIVSLRGDPPEGIGERYIP
HPGGYENAADLSAGIRAIADFEISVGCYPEKHPESASLQADIDHLKRKIDNGATRAISQF
FFDADVFLRYLETVRAAGITIPIVPGIMLQPNFKGLKRMAKLCGASIPERLETVFDGMDE
DEKTRELITAHIAADLCDALKAGGVDQFHFYTLNRAELALAACALLGVKPEPAEAA
>A0A4Z1FMC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrytis paeoniae|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRAIDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDGFEQKLRDHPSGAFKNIPIIPGMMPIQSYQMI
KRTTKLSHAKLPSTIITRLDAVRGDDEMVKKVGVDILSEMVEHLKSTKSQYSGPRGFHFY
TLNLEKAVSFILERTELIPDAETVAALEPEYVPTIPDIADLMSIHSSSHKRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSVFGWGPKNGFVFQKAFVELFL
PTADWKTLHAKLTSPELRDTVSFYASNAKGDFISSDEAVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSQTRKIIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLN
>A0A679KCS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp. ghe19|TrEMBL
MEKSLWRSIDRLGPLRPTSLAVTSGTGGTTRERTRLTVERILRETTLAPAVHLTRVGNTR
EEIAATAAAYWSLGVRQLVALQGDSPAGEPYEPGPNDYEYTCDMVADLKGIANFEIAVAG
YPEKHPASATVAADIAALKNKVDAGADRIITQFFFDNKLFFRFEEQARTHGVAAPIIPGI
LPIHNFKQVAAVAARCGVSIPSWLARRFEGLENDPETHRLAAAAFAAEQVLGLVDRGVTE
FHFFTLNRADLVYGICHMLGLRAAEEA
>A0A2H0LWR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG11_big_fil_rev_8_21_14_0_20_42_13|TrEMBL
MSLRKKVESGKFILTSEIGPPKGIETKVILEDCELIRSRVDAINVTDLQSSVMRLGSLAV
SAILKQHGFDPVYQLTCRDRNRLALQSDILSAASLGIENLLLLTGDHQSLGDHPDAKGVF
DLDSVQLIEAVRGLESGVDMAGKKLQGELPRFLKGAVVNPGAEPVEPQILKMKKKIEAGA
EFFQTQAIYEVDKFAKFMEEVRDFKVPIFAGIVMLKSAGMARFMNKNVAGVGVPDNLINE
IDQAKDKQVKSVEIAARLIKELKPLCQGIHIMSIGWDKLVPKVLDAAGL
>A0A4Y4D8T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria varians|TrEMBL
MSAPSAAPQHTRLPVIESPTTTPPTGTSWLVRRPRRSTLVSFEVFPPRPTADPDTVWSHI
DTMAEAGPDFFSVTHGHSADTGVSREALRHLRRTTDTPVMAHFTCGGTDRAGLERSVEQL
LDDGVRDLLALRGDPPLGHGEWRTPPGGISRASELVALIRDVERRRFGDGFRPGTRPLSV
SVACYPSPARGRDFEADLASLWEKQEAGADYAITQVLYEPEDYARFLERARSEGIHIPVV
AGLVPLTSPQRLRRMTEITGVPVPGRLTDFLASGSAEELRCRGIAATLSLIDDLLDLGCA
GFHLYTFNRPDAALAILEHLRVRDAAREYRGRSPAA
>A0A399F4E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meiothermus granaticius NBRC 107808|TrEMBL
MKIGELLERKGPQPVFSFEFFPPKTPKEEARLFEAIAELRLLEPAFVSMTYGAGGAGARS
VEWVGRIQNEVGLTAMAHLTCMGHTREELGNILEQLRGVGIQNIMAIRGDPPKETGGLEA
TQGEFRYAWELVAFIRERFGPAFSVAGGAYPEGHIESESLEADLRHLKAKVERGLDFLVT
QLFFNNALYFGFLERARKVGIEVPILPGLMPITNLGQIRRFMDLCGASIPGPLLSRLERA
ATPAEVVEIRVEHATRQAIELLEAGVPGIHFYTLNKSPATRMILENLAGAVR
>A0A854D1N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium 13_1_40CM_4_54_4|TrEMBL
MKLADLYARPGLTLSVEFFPPKTDKGEENLFNEIEIIKRLNPAFCSVTYGAGGSTREKTV
ELVDRIHRESCLEVMCHLTVVGQSKDEARSILKKLKHKGIENLIALGGDPPQGMADWRPH
PDGFHHAVELVREAVALGGFSVAVAGFPEVHPRAVSRAADLKYMRDKIDAGAVAIITQLF
FDNDDYYRYVEDVRKLGITVPIVPGVLPILSAPQVRRFTALCCAKIPAPLERELAKVEND
DDAAVKLGIEYASRQCEALIKFGAPGIHFYSLNKSLSLRAICKNLCL
>A0A7S6YS33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. Ac-14|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGEHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A1V5T708|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium ADurb.Bin270|TrEMBL
MNDFMKRLREEGILADGALGTEIYKRGIFINRCFDELNISNPSLIKEIHDSYISAGALLI
ETNTFTGSRPALAAHGLDGKVAEINRAGVKIARESAGERAFVAGSIGPISWTRKNSGGMT
DSEMKSFFTEQIEALSDAGSDVILLETFIHLDELHIAYEAAREVSNKPVITQVSLKHLGE
GEFEGLLPEYAAAQMENWGADVIGVNCCDGPQGVFEAIKRMSIATKTPLSAMPNAGLPQM
VNGRLMYLASPEYFAEYARRYAMLGVALIGGCCGTTPEHIKEAKKYLKTMRPGQRSNTKS
IVESISKPVSPIPPEQKSLFGAVIGKKFAISVEVDPPLGTDPSSSIDAAKSLKQLGVDAI
NIADGPRAMARMSPIALASLIKGKVGIETIVHYCCRDRNILGMQMDLIGASALGLHNVLV
ITGDPPKMGHYPEASAVFDVDSIGLIRFISNLNLGLDFAGRPIKQATKFLIGCGVNPGAI
DIDTEVERFRSKIASGAEFAFSQPVYDQKMLARFLEKIKDLSHIPFFVGVLPLVSLRNAE
FLHNEVPGMQIPKHILDKMVSAKSGDAQKKYGLEIARDIVSAAKGSGKISGAYIFPPLGR
YETVEKILKGII
>A0A1A7PYS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallibacterium salpingitidis|TrEMBL
MSYAKEIDVLNRSIADLNGDINVSFEFFPPKNEKMENILWESIHRLKVLQPKFVSVTYGA
NSGERERTHGVVKAIKQQTGIEAAPHLTGIDATPEQLKQIAKEYWDSGIRRIVALRGDEP
PGYDKKPFYARDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLIFLKQKVEAGANRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFVQLQKMAKITNVKIPSWMYKLYDGL
EQDQTTRNLIGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGLRPHLAAA
>A0A2S6ATW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia nova|TrEMBL
MSFDNVRGRSTPGRPSRTPSGTPSVVGQLGRRPDGTIPFSVEFNPPRDAEAEARLWRAAR
EFERMHPAFVSMTYGAGGSTRDRTARITGQLARETTLLTVAHLTAVGHSVAELRSIVGSY
ADAGIRNMLVLRGDPPGDPLGEWRKHPDGVEYAEELVRMVCELGDFHVGVASFPQGHYRS
PDLDHDTRYLVSKLRAGAEYSITQMFFDVEHYLRLRDRVAAYDPEQGAKPIIPELMPITS
LRTVQRAEELSGRPLPPRVMQRLEQAAGNDPEANRTAVRAVGIEIATEIGQRLIDEGAPC
LHFITLNFAKATTEVLTNLGYTVTPAVVSA
>A0A5R8N786|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea sp. KC401|TrEMBL
MPFRGTEDAVLAYVPRTIPVTVTTTEAKGLAATVDLARRLAGHGYSVAPHLAARQVRDGR
QLTDLVTELREAGIDGIFVIAGDVARPAGGFPDALSLLEALDANGHHFRRIGIGGYPEGH
GSIRQELIDRAIELKARYATHVITQLCFDAATISGWARRLKERGVGLPIHVGLPGAVSRQ
KLIRISAGLGLGQSARFLNKQQSLLWRFFLPGGYSPDRLVERLAPRVCDPEGNLAGFHLF
TFNELEKTESWRRGMLLRAGYHT
>H5X1S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora marina XMU15|TrEMBL
MSLGRAFAAGRFAVTAELGPPRGADPGQVEARARVLRGRVDAVNVTDNPGATVRMSSLAA
AVLVLRAGVEPVMQLTGRDRNRMAVQADLLGAGALGIPNVLLLAGDPPGGQAVPVFDLDS
VQLLWTARTLRDRGRLLSGSRVDPPPHWRIGSVENPFVPTVRERAARLGTKIAAGAEFVQ
TQFVFDVAGFARWMAQVRALGLHERCRILAGVGYPRSPAMLHHLRTGLPGVRVPDEVADR
LLGVPPHRFRQEGLRLCTEIIDRVREIEGVAGVHVMAFGDEAAAVEIVERAGLTG
>A0A2I0F302|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moritella sp. Urea-trap-13|TrEMBL
MKYSIELVPRSWETLNTEVEEVSQFGQINTLNIPDLLRFDVRSWDACDRLQDKFDEVIPH
LRAIDFDLRNGFPLTDFFRHSKINSVLVVEGDPPQDISHRTYRNTSCELIRIIKKELPYM
KVYAAIDQYRTSMRKELDYIHDKIDAGVDGFFTQPFFDLKFLDVYMDMLQGTEVFWGMSP
IHSETSQSYWENKNDVVFPSDFEPTKEWNIKFGRAMIKKVQARDDNVYFMPIRANACEYL
GKLLAED
>A0A511CXI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia asaccharolytica DSM 44247 = NBRC 16224|TrEMBL
MIERISQDGPVFSVEFFPPKDEIGEAELWRAIRKLEPLDPAFVSVTYGAGGSSRERTIRT
TAGIATDTTLVPMAHLTAVAHSRSQLRHVIGAYAGAGIRNVLAVRGDPPGDPLGEWIPHP
EGLTYAEELVDLVRSLGDFCVGVAAFPYGHPRSPDAESDLRHLVAKIRAGADFAISQLFL
EPEGFLRLRDRFVAVGSDVADVPLLPGVMPLTTLRTLRRGPELSGAPLPPELVERLERYA
DDPVAFRAAGLDATAELCGKLLAEGVDGLHFYTLNRSSATVELVRRLGLVEHRR
>A0A285QHL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas guangdongensis|TrEMBL
MTTPTYTLSEAHRALAAPLFADLAGDVAVSFEFFPPKTDKLDGALWEAVSTLRPLDPRFV
SVTYGAGGSTRERTHATVARIVRETGIPAAAHLTCVEASRDEIAAVAEEYWASGVRHIVA
LRGDSPQPGERYHPPADGYENAAALVAGLRRLHPFEISVAAYPECHPDSEHAVADLDNLK
RKLDAGATRAITQFFFEPDTFFRFRDAAAAAGIGAEIVPGIMPVTNYASVARMSAMCGTA
VPAWLKRLFEGLDDQPQMRQLVAVTVAAELCRRLYAGGERAFHFYTLNRAELSYAICHLL
GVRPVREAAVAAA
>U1Q107|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobaculum sp. oral taxon 183 str. F0552|TrEMBL
MAGFWRTIDELRPARPDFISVTYGAAGKDRFSARDIVTRLCRDTPVSPIAHLTCVNTSVS
TVEAVIEDYLDADVRTFLALRGDPPIDDPDWSPPPGGVSSATELVALIRSVETRRCARHA
SAALRAAVNPLTIAVAAFPSGNPAAGTSPAQEVERLLLKQAAGANFAITQLFWDPEVYIS
FVDDAKRAGVTIPILAGLLVPTDIERLSRTAELTGIDPPQALSQTLRDAEGAEAAVQAGI
LATARVARAVLGSGAPGLHLYTYNKARPSLGLLARIGLFDPAA
>A0A1S2CDS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. AC-23|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQVVRDQLAGVNPDFFSVTFGAGGSTRDRTIETV
VNLHKQGISTAPHLSCVGGTRAEIAELLDVYKENGINRIVALRGDMPSGMGASGEMRYAN
ELVAFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVEAGANSAITQYFFNPESY
FYFIDRLEKLGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTVSIRK
FGEEVITEMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISERDKIAF
>R5QNV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:194|TrEMBL
MKQGILFDLDGTLWDSAQAVVDSWNEIIETLPDFHKLITNEDMCQLMGKTMDDIAYTYFN
TVSKERALEILQICMDHENAYIEQHGGVLFPGLEEVLKELSEKYDLFIVSNCQLGYIEAF
LSYHKLGKYFKDTECYGRTKRCKGDSIAILLGRQDLEQAVYVGDIEGDFISATQAGLPFI
HAAYGFGKVPQAVYAIRSVQELPAMAKKVFAKKDIRAFLHTQKLITDGAFGTYFSSICQN
GIFPERANTQAPALVKQVHEAYLSAGAQLIRTNTFAANTKTLDMGLDEVLETIEAGFTIA
KEAAEPYRQKHPVFLAGDIGPIPGGRQEQEEQITEEYLQIARKFVALGADLLVFETFPNP
DQILPVIRQIRKESPIFILVQFAVNQLGYSVAGISARSLLEEAGQVTEIDAAGLNCGVGP
GHMYNIIKQVSSLSGKYLSVLPNASYPKVVQDRLVFLENMDYFSDKMVEIADLGASIIGG
CCGTNPDYIRRLVKALGEKHLRAEKPSPVHITVKERTEQAEDHSFYAGKSGKLIAVELSP
PPSANDQKLLEAAHLLSAMHVDTVTFPDSPSGRTRADSILMAAKVARETDLCVMPHICCR
DKNAIAIRSQLLGAYLSDIRNALVITGDPVPSMAREDVRSVFNFDSVGLMKLVQEMNREE
FASDPFFVGGAINQNRLRLDVEINRVKRKMEHGATFFMTQPVFTKEEIDKIRRIKEETGA
RILCGIMPLVSRKNALFIKNEMTGMCVTDEIVARFADGMSRSEGEAAGCAIAREMMALAA
DFADGYYFSIPFNRVYLLHDMTGVINESGKEK
>A0A0C2CE87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylostoma duodenale|TrEMBL
MVDVLKESAISNGHSNHGHLKKIDSLSAIPYMGSVPNLHERSSSDEEHLSFEVGHGNKYV
PLHERINRRIKDKTPFFSLEFFPPKTANGVANFFTRLDRFNEGGPLFVDITWHLGSDPAN
MNKETSSSSIAAGCLDYCRVDTMLHMTCAQYSKEQTIKHLEQSKSVGLRNILALRGDLPN
IDTDGITIYKYRALDMIRWIREEFGDYFTIACSVCGNLAMLNSNDCVRPYLRLIAFSLLA
TAKVNLAAI
>A0A1Q7MEA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenarchaeota archaeon 13_1_40CM_3_52_10|TrEMBL
MRLSDRARHHNLVTVELIPDRVVPGDLALLRGRVDAITVPALRNGHDDPSYPKSFAVTPQ
RRSLASAAIINRAGITAVPSLTCRDCRRSDLSMISSQVEDGLGNVLIVYGDPYPEPRPGT
YEFTKTNELIREISSLNGGSDPCIGAVTNQHVSNRESEISRTISRVDAGADFIVTNVAFD
SESVLEHRDSLLEAGLNVPLLIQVSIPLSLDNVLFVSHKFDIPVPVHVRKKLLNDPAGGS
LAVAAEAYEALHGEANGIHFSYLFRQRNPIPTYRHLLETIGIEGPALAPLATSAVKTYSA
L
>A0A098RRM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. H41|TrEMBL
MIIKRIMHTLPDISATSVIPASIEASPAQVLGPASLAGLFPQGVRVYLTDTGAASQVKLV
DAAKHLRDLGYEPVPHLAARRIASRIDFEEQVKRLAGDAGVTDVLAVGGGVEKPEGPFTS
TIDMLSTGIFDRCGIKHIAIAGHPEGSPDFNDETATAALRLKRDFGERTDAAMRIVTQFG
FDSARFIAWAEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LARGHSPESIVGPIERHWRDNPQGPIRQIHVFPFGGLQASSDWLVSRGSWRTKNADHAAA
TGSVAI
>A0A2R4F8Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax avenae subsp. avenae|TrEMBL
MSLSTHKADLPVSFEFFPPKTPEGADKLRAVRQQLYALRPEFCSVTYGAGGSTQEGTFGT
VREILSEGVQAASHFSCIGATREGVREQLAQLKAMGVSRLVALRGDLPSGYGAGGEFHYA
SDLVAFIRAEAGDDFHIEVAAYPEVHPQARSPEADLQAFATKVRAGAHSAITQYFFNADA
YWRFVDDVRALGLDVPVVPGIMPIMGSTQLMRFSDACGAEIPRWIRLRLQGFGDDSASIR
AFGLDVVTELCERLRAGGVPALHFYTMNQSAATLEICRRLGL
>A0A0P6W0R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecomicrobium hirschii|TrEMBL
MTGAQFDHLLGSTAPIRVSFEFFPPKTEKMEETLWSCIERLAPLRPSFVSVTYGAGGSTR
ERTHATVARIIRETDLAPAAHLTCVDATREEVDQVVRSYKAAGVRHIVALRGDPADGMGR
KYQPHPGGYASTPDLIRGIRAIGDFEISVSAYPEKHPESPDLPADIQLLKRKVEAGATRA
ITQFFFDNDIFERYVDRVRAAGIDIPIVPGIIPVLDFERTAGFARRAGASVPAWLAHRFE
GLERDDKTRQLVAATVAAEQCFDLVKRGYRDFHFYTMNRADLVYAIGHLLGLRPAPDAKA
AAAASPVGAAA
>A0A2A3IEB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 2321.6|TrEMBL
MRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALRGDPPGDPMGEWVKHP
DGIGYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVAKCRAGADFAITQMFF
YPEDYLRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQQS
>A0A4V3L3E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.205.01.1.1|TrEMBL
VPGIHIPDAVIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSGIHVMAYRQEEYVAEIVD
ESGVLKGRQPWKREIRRDDQMVADRLDRILHEDITE
>E7G956|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprobacillus cateniformis|TrEMBL
MKNKATISFEVFPPKNKEGDISSIYRTIDELAKLNPDFISVTYGAGGSTKGKTVEIASKI
KNDYHIESVAHLTCISSTKEEVLAMCQQLKDNNIENILSLRGDYPRDDSFDKEKLEFHYA
KDLNTLITNEFPHDFCLSGACYPEVHTDAACFEDDLKALKEKVEAGAEYLITQIFFDNNY
YYRLVKEARKRGITVPILAGIMPITNSKSLLHTAKMCGCSIPYQLSTMIESYYNYPSAMK
EIGINYATHQIIDLITNGVDGIHIYTMNRPEIAQAIFRNIPTVLKELNHE
>A0A2E2EIX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovoraceae bacterium|TrEMBL
MAKVIDHIKQAKGKTLFSFEILPPMKGDGIQKLFNQIEPLMEFDPKFIDVTYHREEYMYK
KREGGLLEKVSLRKRPGTVGICAALMNRFHIDTVPHIICGGFTKQETESALIDLQFLGID
NVLALRGDAIKSEAHFVPTTGGHEFASDLIQQIQSMNSGVYLDHEVKNAFPTDFCIGVAG
YPEKHFEAPNFETDLKHLKNKVELGAEYIVTQMFFDNNKYFEFVDQCRSQGINVPIIPGL
KPLSTLKQLTILPSIFHIDLPSDLVQSAEKCQNNDQVRQVGIEWAIQQAKELKQHGAPCL
HFYSMGKSDNIVKIAKEIY
>A0A2S7L1T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter filamentus|TrEMBL
MKVTEHIKKANGKTLFSFEIIPPKKGNNIQDLYNNIDPLMEFKPPFIDVTTSREEYVYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDIDTVPHVLCGGFSKEETEYLLIDCHYLGIQN
VMALRGDAMSHQKYFEPSKNGNHFAKDLVAQINDLNCGKYLHDVMEADHKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNKKYFKFVEAAKKAGINIPIIPGIK
PIAVKRHLQLLPQVFKIDLPEALINSVESCKSNTDVRQVGIEWTIQQSKELLAAGVPVLH
YYSMGKSDNIEAIAKELF
>A0A2N6TDT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium kroppenstedtii|TrEMBL
MSSPNSAHTPTNRPPRPIYQQVPVSQAISLPTPGPVPFSVEFMPPRDDAAERRLSDAAAT
FHDLGASFVSVTYGAGGSSRSRTIRIGQELAHTPLTTLVHLTLVQHTVDELKEIIASYQE
CGLTNILALRGDPPGDPAGEWVSTPGGLEHAIDLIKLIQECDTQRQFEIGIASFPDKHYR
ATDLDSDTAYTIAKLRAGASYSITQMFFDVEYYLRLRDRLAAADPVHGAKPVIPGLMPIT
SLKSLRRQRELAGCRVPADLEERLEKATATGDPSDPRVRQEIRKIGIAHTTAMAERLISE
GAPDLHFMTLNFARATQEVLHNLGMAPAWGTDHGHDAVR
>A0A2W5SQC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium kroppenstedtii|TrEMBL
MSSPNSAHTPTNRPPRPIYQQVPVSQAISLPTPGPVPFSVEFMPPRDDAAERRLNDAAAT
FHDLGASFVSVTYGAGGSSRSRTIRIGQELAHTPLTTLVHLTLVQHMVDELKEIIASYQK
CGLTNILALRGDPPGDPTGEWVSTPGGLEHAIDLIKLIQECDTERQFEIGIASFPDKHYR
ATDLDSDTAYTIAKLRAGASYSITQMFFDVEYYLRLRDRLAAADPVHGAKPVIPGLMPIT
SLKSLRRQRELAGCRVPADLEERLEKATASGDPSDPRVRQDIRKIGIAHTTAMAERLISE
GAPDLHFMTLNFACSTQEVLHNLGMAPAWGTDHGHDAVR
>A0A1X7EBH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Amel2xC10|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFYAPKTPQGEKSLWNALRRVEAVAPDFVSV
TYGAGGSTRATTVRETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSTAWDTDVEHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPRLSNAHF
PGELKERILTAKEDPATVRSMGIEFATEFCARLLAEGVPGLHFITLNSSTATLEIYENLG
LHHPPRV
>A0A2R4EDV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax avenae subsp. avenae|TrEMBL
MSLSTHRAALPVSFEFFPPKTPEGADKLRAVRQQLYALRPEFCSVTYGAGGSTQEGTFGT
VREILSEGVQAASHFSCIGATREGVREQLAQLKAMGVSRLVALRGDLPSGYGAGGEFHYA
SDLVAFIRAEAGDDFHIEVAAYPEVHPQARSPEADLQAFATKVRAGAHSAITQYFFNADA
YWRFVDDVRALGLDVPVVPGIMPIMGSTQLMRFSDACGAEIPRWIRLRLQGFGDDSASIR
AFGLDVVTELCERLRAGGVPALHFYTMNQSAATLEICRRLGL
>A0A1I2BNV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes philippinensis|TrEMBL
MALGLPSRLPGAPSIGDLVRGPAPTFSFEFFPPKTPVGEQRLWQAIRELESLRPDFVSIT
YGSGGSTRDTTVAVTERVATETTLLPMAHLTAVDHSIAELRNVIGRLAGAGISNILAVRG
DPPGDPTGEWVKHPDGVLYAEELVRLIRDSGDFSVGVAAFPYKHPRSADVESDTRDFVRK
CRAGADFAITQMFFDVDDYLRLRDRVTAAGGDTPILPGLMPVTQMATIERATVLSGAPFP
AALLPRFERLAHDPEAVRALGIELCADMCARLLAEGVPGIHFITLNRSTATREVWQLLAP
AEAATAAA
>A0A352DYK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MSVTPLHDAYASGRFGLSFELFPPKTSESEAMMWRTVDELMAWEPALVTCTYGAGGSTRA
KTLDVIRGVRDRHDVAVASHLTCVGSTVSELRDYLQAAREHGVSAIVALRGDPPQGAAAF
TPVDGGLRYAAELVALIRETFPEFGILVAGYPETHQEAVSAEADLENLRRKCDAGGDVVI
TQLFYDNADFLRFRDACDRIGIRAPIVPGVMPVTNYAQIRRIASLCKARLPEAFTSSFEA
AGDDEAAQFEAGVTFATRQVRELIDEGVPGIHFYVLNRSPATVRVLEDVGLSRGVRG
>A0A561X0K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. C56-T2|TrEMBL
MGLLDELKQRVLIADGAMGTLLYSHGVDRCFEELNLSKPEDIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGRAYVLGTIGGLRTLNKSAVPLDEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYYMLQSLEEVPLPTRAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLLGGCCGTTPKHIEAMARALQDRTPVTEKTVKRRAVPVS
VQSDIPSSATPLPELVRARRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLA
TPRISNAAVATIIKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVER
MEKKIECGAHYFLTQPIYSEEKIVAVHEATKHLYAPIYIGIMPLVSARNAEFLHHEVPGI
TLSDEIRARMAACGDDPVRAAREGIAIAKALIDAAFDLFHGIYLITPFLRYDMTVELIRY
IHEKEAATKERKVVHG
>A0A1W2CNF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. URIL14HWK12:I5|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSTERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DGDKHQEAMHWMRRQATPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETVQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQARIHTLDQWAPA
WRASWQMPGLPAVTFHPPQAGWRQGESRVDASLKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQRLWSTPVGAQVLHKVERAVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFQAATP
RRLSPQPAPRSQPES
>A0A3A8G6K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter cumulans|TrEMBL
MSLLFSYFQQNQFCILVEYLTSLNEIFPVKKQFAGYPAVMTLADRVHSDHDTSPLEASKL
YPQDLEKVLHFAGKGRDIHDFENFLKQARKADIQNLLLLTGDKLKEHSNGENGTARSRYL
ESVNAVMAAKKTGGFCIGVAFNPFKYAEAELDAQYLKLHKKIKAGADFIITQLGYDIQAL
KQAKAFLTQHHYPQKILACVMPLSLARAKFMLKHQVAGIVITPSMLKVLEEEKQAGLSER
VYLRCALQILICKQLGFVGVDLSACHKPAEQALLESYIEQYRHLDLNALEKLWNELWQIH
TGAELQPELSYFSRPPSSKQLFKYHQLHLMHDALFDSKLGKGVGRFIFKAPIWERSTAAK
TLLKTEYISKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVQQTQVLKEKLIPTVPIEVRGTSSWKNWYLAAEA
>A0A6I1NHL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MWU12-2323|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLQQYKGAGIQRIVALRGDLPSGMGMASGELLHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEADLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQAFG
EQVISQMCDRLLEGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>K4RDJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces davaonensis (strain DSM 101723 / JCM 4913 / KCC S-0913 / 768)|TrEMBL
MGTAGLKALLHRVRYEVLPAKSTEDKVLAHVPRDVVVTVTASPVKGLEPTLDLTARLAAH
GYRVVPHVPARLLRDDRHLKEVAGRLREAGVDDVFVPAGDADPPAGGFEGALPVLRRLSE
LGSPFARVGVTGYPESHPLIHDDVTIQAMWDKRAYATYIVSNLCFDPRVLGEWLARIRRR
DVALPVHVGVAGPVQRTKLLAMATRIGVGESTRFLAKHPAWFARFAAPGGYAPERLLTRT
QEALTAPSAGVAGLHVFTFNQIAETERWRRALLDRLGG
>A0A259D3J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp. 17-45-7|TrEMBL
MKSHQEKLAFSFEFFPPKTAEGMDKLREARKELAKFNPEFFSVTFGAGGSTRDRTMETVL
EIQREGYQAAPHISCISSSKAEIRDLLHTYQSHGIKRLVALRGDVPSGEVSAGDFKYAAE
LVEFIRAETGDHFFIEVAAYPEFHPEAKTPTADLQNLKRKMDAGANSAITQYFYNSDAYF
RFVEQCDSFGITMPIVPGIMPINNITQLARFSNVCGAEIPRWLKMRLEEYGDDMASIRAL
GIDVVSELCETLMVWGVPSLHFYTLNQSATISTIINNIKD
>A0A1G6J5K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. LaPpAH-199|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PEALKERILAAKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>H3KAK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megamonas funiformis YIT 11815|TrEMBL
MTRISVELVPRDIEVLKEEVKTIKEKLSDVDFINIPDLLSCDTRSWDGANIAKAYFDDVV
PHLRAMDFDFTKELPIKDKLREYNIKKVLVIEGDPPQSMLYQVYPTISTDIIKKFSEEMP
EITVYAGIDQYRSSMKEEEYRIRRKQLAGAKGFFTQPFFDMRYLEMYADLLDGLDIYWGV
SPVLSERSVSYWRNKNNVIFPKDFEPTLEWNIEFARKVIDFARKHNHNVYLMPIKAKIMP
YLEGVFAK
>A0A5D0VM80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. BW6|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGVSTAPHLSCVGGTRQEIGELLDLYKEHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVHAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A1G3IME0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium RIFCSPLOWO2_12_FULL_67_15|TrEMBL
MIEALAPLAGDVRVSFEFFPPKTEGAELSLWTCIQRLAPARPAFVSVTYGAGGSTRERTH
ATVLRIRHETALEPAAHLTCVGATRAEVDAVARRYWNEGIRHIVALRGDPPNAPGPGLGV
YRPHPGGYAFAADLVAGLKRVADFEISVAAFPETHPEAQSPAADLDNLKRKIDAGASRAI
TQFFFDPDVYFRFVERARGAGIAVPIVPGILPVTNFARVREFAKACGASLPPWLANLFEG
LDEDAETRKLVAVSVAAEQCRLLFAGGVRAFHFYTLNRADLVYAICHILGVRPPKAEPAA
ALEPAR
>A0A261VD95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella genomosp. 12|TrEMBL
MTDSTSPAFSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTEDTVRT
LTNLGCDAAPHLSCIGASREQLREILNNYRQAGVHRVVALRGDLPSGMGGDAGELRYASE
LVRFIREETGDWFHIEVAAYPEMHPQATSPSVDLDHFVAKVQAGADAAITQYFFNADAYF
DFVDRAQARGVSIPIVPGIMPITNYSQLSRFSEMCGAELPRWIRLRLAEFGDDKASIRAF
GQDVVTELCQTLLDNGVPGLHFYTLNQSEAILGIWKNLQR
>A0A0L0LT78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium breve|TrEMBL
MHSPMFTLEVFPLKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQAVGEFNHASDLV
SYIRSVKPDLKVFGACYPEGHYQADTIDQDIENLKIKVDAGATHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A061B4M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyberlindnera fabianii|TrEMBL
MRISHKLQKAHEESDKATFSFEFFVPKTSQGVQNLYDRMDRMYNLNPEFIDVTWNAGGRL
SNLTTDIVSTAQSVLGLETCMHLTCTNMPIELIDNALKDAYDSGCQNILALRGDPPIEGG
EWTAVEGGFTYAKDLVKYIREKYGDHFDIGVAAYPEGHPEESNVDSLIDHLKEKCDAGAD
FIITQMFYDAENFIEWCKKIRSKGITIPIIPGIMPISSYAAFKRRATWCEINIPENFEAK
LQDIKDDDQLVRQAGTELVAEMCQKLLDSGYVNHVHFYTMNLEKSSIMILETLGLITANN
VDFLPWRKSLNPNRTNETVRPIFWKNRKYSYINRTKNWDEFPNGRWGDANSAAFGDVELF
TSGLLRQSPKRAMELWGEPTSVKDISNLVVSYLQGKIGSLPWSDTPVTSEVNSFKEQLID
LNNRGILTVNSQPRVNGATSNDPSYGWGPKNGFVYQKQYLEFLIPKTKLNNFIQKIDEIN
KPFNTSNNDKDNYNILTFFAIDVNDDLNSNTKDDSANAVTWGIFPGQEVLQPTIVEKVSF
LAWKDEFYRIIAEWSHIFEEGSISRQIIKSIIDDYALVNIVDNDYVGNDKIFSLLQDL
>A0A7Y1TGZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eudoraea sp|TrEMBL
MKVTEHIERAKGETLFSFEIIPPVKGRSIKELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYDVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNI
MALRGDAMKGEQYFEPTKGGHKYASELVSQIRNLNSGQYLHEVIETDNCSDFCIGVAGYP
EKHMEAPSMKTDLKWLKKKVDLGAQYIVTQMFFDNQKYFDFVTAAREAGIDVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIEEVEKCRNNTAIRQVGIEWAIAQSKELKDAGAPVLHY
YSMGKSDNIREIAKAIF
>A0A0B0Q9Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurospirillum sp. MES|TrEMBL
MVESFIEKLRSDTFLSLETTPMHEPTFEPIIEKIASLKLDQKVDGFSTTDNPLARLKYNA
LMGALKLQHRFHKPVIATMSMRDRNKLALQSDLLGANEHDLRTILCLTGDPAGASDQPQL
KGVFEGNSTLLMEIIQCFNASIDYSGKPFKTPPKPIYPFAVCNAHANTPKHLAKKMATKI
SHGAIGIITQPVYSEENARMLLELFDEAKTLSGKKESPCELILGFFPIVHLRTAQFLSAH
VPGVHVPDIWTEKLLHAKKIGENEEKKVGFELSLQTFQTLRRVHPKTHIMSANHFELIAD
ILNA
>A0A846RW87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium marinum|TrEMBL
MVANSATDVLHDFSLEMTGKDVSNLQQAASAIPPGTRVNVTFLGNENLEMRVEAAKEVLE
LGFVPVAHVSARRLASEADLREFLDALQQAGASEHVFIVGGDPATPEGPYPDSLTVIRTG
ILQEYGVREVGLAGYPEGHPDISSDTLWEHMAAKNSSLAEQGLDQVVLTQFGFDAEQVAD
WVHEVRARGIDSEIRIGTPGPAGIKRLLGYARRFGVGTSAGIAKKYGFSLTNLLGTAGPD
RFLTDLSAYDSIIGESSGVKAHFYTFGGLTTTAEWIRDFRVKT
>M3AA53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum caucaseum|TrEMBL
MTPARWHQALSLLRPLVSLIGRRRLEQPLAWAERALKRRLFGCRMCGQCALDATGMGCPM
RCPKGLRNGPCGGVRSNGTCELDASMACAWKDIWSRLDGELPPRQPLLDHRRAGRSAWLA
EILDPKPAAPDLPPDRAFAKGRLQARLEAGDFVVTAEIGPGTAADGSALLAQAGKLGPWV
DAINVTDGSAAHCALSSMAAAALLRRAGHDAVMQMTCRDRNRIALQNDLLGAAALGIENV
VCLTGDGVLNGDHPEAKPVFDLDAVALVATAKTLRDGGRFLSGRALTVPPGYFIGAVDNP
FAPPEPARVQRLAAKVAAGAQFVQTQYVFDIPAFTLYMERLRAAGLHRRCHVIAGVGMVA
SARTARWLTAKVPGVRIPDGVVRRLEQAADPVAEGAALAVELIGALRRIDGVAGVHLMFH
HHLEMIEGVITAAGLAGPRQRRRVA
>A0A7Z9K306|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MGVSFEFFPPKTPQLEKSLWCSVERLAPLNPVFVSVTYGAGGSTRKKTHKIVTRLQNKMG
IPAAAHLTCVAASKAEVNRVARRYWEAGIRHIVALRGDPPDGQGKYVAHPEGYNNASDLV
RGLKQIGDFEISVAAHPEGHPEAKSIEADIENLKRKVDEGATRGITQFFFQPEHFLRFRE
KTQKAGLSIPIIPGILPVTNFSQVRRFSKICGASIPHWMSTLFEGLDNDPDTRLRIAANI
AIDLCRILKAEDVTNFHFYTLNRADLTYAICHVLGNSRNTQPKIAL
>N6XYH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera sp. 63|TrEMBL
MSIDISIEFFPPNTAEGAEKLRTTRDKLAALKPAFFSVTYGAGGSTRERTFATVKEIAAA
GYEAAPHLSCIGSTRDSIREILQEYADAGIHRIVALRGDLPSGAGAAGEFRYANELVEFI
RAESGDRFLIEVAAYPEWHPQARSPKDDLLAFKRKAEAGANSAITQYFYNLDAYLYFVDA
VRKLGVDIPIVPGIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDADAIRAFGLDVV
TRLCEKLIAEGAPGLHFYSMNMAGPTTEICRRLGLQN
>A0A1Y5FB13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovorax marinus|TrEMBL
MKIIEHLDRAKNKELLCSYEIVPPPRGRSVQDIIDIVEAIQPYNPPWIDVTSHAAGAFYN
EKADGSIERKIFKKRPGTIGICGIIQNRFNIDTCVHLLSLGFTKEETEDALIELNFLGIH
NVLALRGDAPNYNKKIDKTRHTNKYAIELVEQISEIKRGEFLHDISGARPLDFCTGVAGY
PEKHFEAPNMSFDIKMLKAKVDAGADYITTQMFFDNEKYFSFVKDCRDAGITVPIIPGIK
IIKNLNQLASIPKHFYVDFPNEFVDEAMENQEHIKDIGLEWAMKQCQGLVDAGAPCLHFY
IMNDTKSVIEVVKKFR
>D0SAC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii SH046|TrEMBL
MSKKVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGADIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A517RPZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia alba|TrEMBL
MRISELYRSGTFDLSVEIFPPKNESGDAELFRTLEELIRYQPAFVSCTYGAGGSTSKRTI
ELCETIQNQLHTTATAHFTCVASTRDQLIEWLHSASEAGITNIMALRGDPPKGQETFVPA
DGGLKHANELVALIREHFPQMGIGVAGYPEVHPESPDAETDLTNLKRKVDAGADAVYTQL
FFSNTHFHNFRERCVQAGITCPIIPGIMPITEFRRIQRISSMCNSEFPVELTEKLEAVQD
DLKAQFEIGVEFAIRQCQELIDDGVPGIHFYALNRSLACKRIFEALGFHEA
>A0A1M6ZD92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWEL|TrEMBL
MKIIDILKQDKMSLSFEVFPPKKETSFDSVQAATESIAALGPAFMSVTYGAGGGVSQYTL
QIAKNIKKKFGVPMLAHLTCVSSSKETVQARIQDMKDAGITNVMALRGDLTPELIANGRS
DCDYHHAVELIHDLKASGADFCIGAACYPEKHPESPNQREDIQHLKEKVEAGADFLTTQM
VFDNNLFFNFLYKLREAGVTCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGIMRNVSAILGKNFIA
>A0A4U1HI20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trinickia sp. 7GSK02|TrEMBL
MKPIEISFEFFPPKTPEGIEKLRETRKQLALLKPKFVSVTFGAGGSTQQGTLDTVLEMAA
DGLEAAPHLSCIGSSKDSLRGILNQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFWIEVAGYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDREAIRAFGLDV
VTGLCQRLVDAGVPGLHFYTLNASAATKAICERLGV
>A0A1F4F806|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_68_20|TrEMBL
MEVAALYAEPKNWPVFSAETFPTENWRSIDPVLKAVEELLPHGIRVVTTTWGALGSPRAG
TPSISRIIRERFGIPTVVHLNIQGKTRQDLEGILRGLHLDGLHNILALGGDPPVGRKDYV
PAQLRHRYGSDLVNQIVNLNRGRWLGPDGEYTRDGVKTNFGIGVAGFPEVHPSDYRESDG
FEASLKRHIGHVKAKVDAGGQYVVTQMLFDAELYLRFRDAATRAGIGVPIVPGVIPFVSR
NQVARFVGPELRISVPRALEEALRGAGEAEQGRIADEHTGALVEKLLEAGAPGIHFYSMN
QSAPTIRVLKRLGD
>A0A8C4Q542|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eptatretus burgeri|TrEMBL
SGQMPVGETVESAGKEGRQSGGSQQAVSRRGRRTSGWTPAGLRLREAMEHRLTSGDPWFS
FEFFPPRTPNGATNLIARFLFTFNRNFRYLDLSRFQKILNKLLRLGLRSLNTTRSCFEEG
EGFHHAGDLVRHIRTEFGDYFDIGVAGYPCGHPEAKSYEEDVMYLKEKVDAGADFVITQL
FFSASSFLKFLTDCRRVGITVPIIPGIFPIQSYDSLRQLSRLSGLAVPEELHLAVERVKD
DDAAIRNLGVDLAVSLCLELLTAGVSSLHFYTLNREFATETILRRLGLWQQEPRRMLPWA
ISADARRHAEEVRPIFWATRPKSYVHRTQAWDEFPNGRWGNCASPAFGELKDYYLFYLKG
RASKEQLLMEWGPELTSEQDVWDVFTSYITGNPNRQGQKVTCTPWNDEPLSAETLDLRDW
LAKLNQRGVLTINSQPRVNGEPSTHPAFGWGPPGGFVYQKAYLEFFTCAENIKALLLVLK
RYELRVNYHIISSQGWAVTNLPDFQSVAVTWGVFPGSEVIQPTVVDPVSFTYWKDEAFAL
WTERWGKIYHEGSQSRSIVSTMRNSYHLVNLVDNNFPFTSCLESILEEMFAARADFHSVL
TGKVDEADNGQDGGKQIRKSCGDGNYEGITI
>A0A1V4Y0R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophus sp. PtaB.Bin001|TrEMBL
MSAMDNIISRMIRTPLIFDGAMGTMIYEKGIFIQTCYDELCLTNPGLIREIHEQYVQAGA
EVLETNSFGANRIKLRPYGLAEKVIEINRAAAKIARLAAGRTLYVAGSVGPCTQGGQVIT
GREIAEVETAFREQMAALTAEGVDLLLLETFSDLKELKLASRVAREMGVSVLASFAVDDE
GETASGTPAESIAAVLDADPNVDAIGLNCGTGPSGIYEALLKILPVTDKPVVVMPNAGMP
RAVGGRTLYLANPEYFTEYAKKFVELGVRGIGGCCGVHPAHISTMARAVRGLSGIKKHIE
VVARPPAPTQQHVIPTAAKSRLAAKLCSGEKVTSVEILPPRASDFGSMLAKVRRCREAGI
DAINIPDGPRASARVSPMITALVILKEVGIEPVVHYCCRDRNLIGMQSDLLGGYAVGLAN
YLIITGDPPKLGNCPEATGVFDVDAVGLTSVIHNLNSGWDIGGSPVDPPTGILIGVGANP
CAVDLEREIDRYFQKIEAGAEFAITQPIFDVDALFRFLDRVEKYSKRIPVLAGVWPLLSY
RNAEFMNNEVPGVVVPQDILDRMAECETGEESRQRGIEIARTICARIHDRVAGFQVSAPL
NNVEIALSVLGKIDCKDA
>A0A8B9TB14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anas platyrhynchos|TrEMBL
MDTVQGAAEKVCWHVQPKTTRSKMTSTDARGSSSKSDGGSSSGSESSKDSSRCSTPVLDA
ERHERLREKMRRRQDSGDRWFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAG
DPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGD
PAGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYESDLKHLKEKVL
AGFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRN
YGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREE
LLKMWGEELTCEESVFEVFTCYISGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNR
RGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYESRV
NYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWA
KLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A822IIH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ranitomeya imitator|TrEMBL
MMIASTALNYCGLETILHMTCCQQRQEEISGHLHRAKQLGLKNIMALREDPVGDHWEAEE
GGFSYATDLVKHIRNEFGDYFDICVAGYPKGHPDAESFEDDLKHLKEKVSAGADFIITQL
FFEASSFFSFVKACEDIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQTIKDVIEPIKD
NDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDPRRPLPW
AVSAHPKRREEDVRPIFWASRPKSYIYRTQGWDEFPNGRWGNSSSPAFGELKDYYLFYLK
SKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWNDEPLAAETSLMKE
ELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVL
KTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFA
LWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFLLDNCLWQVVEDTFELLNRHTTK
KEAQAP
>A0A838H8L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriales bacterium|TrEMBL
MCGRIEATGRSCVPYGRGVDLQRRIVEHQGEFLLFAVTPPRRATSPEKSQEIADVTVKRL
LALDLDGLVLYDIDDESDRNAEERPFPFLPTMDPAEYLSRHLNDWNLPAIIYRAVGRYAE
PQLRSWLGAQEPDRNLSVFVGASSRDKPVMTSLTRAQALRSEVKPDLLLGGVAIPERHTR
NGDEHLRLLAKQAAGCSFFITQVVYDVNAAKNLVSDYRYECAARGQDPVPIVFTFSVCGS
LKTLEFLRWLGVDVPRWIQNELRHADDTLDVSFEQAQATALELIAYCRRLGVPFGLNVES
VSMRRTEIESSVRLAARLQGELRRSD
>A0A7J9VVN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriales bacterium|TrEMBL
ADIVRRLESYGDDRAAVRAAGIELATGLCDELLAGGAPGLHFYTLNRSKATREIFANLSV
HA
>A0A7Z1WC19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MSLLAQYFAQQQFCVLVEYLSAHQAQWPVKTQFAGFPACMTLADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDAKTRGQKNLLLLTGDKLKQHCYSHDLEPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMAAL
QDAHAFLARHQYAQKMLACVMPLTLARAKFMLKHKVAGIVITPHMLQVLQQEKEQGLSDR
VYVRCALQILMCRHLGFAGVHLSACHQPEEQVLLESYIEEYRHLSFAECEQLWNTLWQVQ
TSTEFHPKLAYYSRPATSSQIIKYQHLHLMHDVLFESKLAKGVGRFIFNFNVWDRSRAKQ
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTKILKEKLIPTVSIAVRGTSSWKNWYVEAAG
>A0A670Z019|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonaja textilis|TrEMBL
MVNEFLPMSNGLGTRSDGGNSSSSGESSQNSSRCSTPILDTERHERLREKMRRRQESGDK
WFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMMATTALN
YCGLETILHMTCCNQSRETITAHLQKAKRLGLKNIMALRGDPVGEEWEEELDGFNHAVDL
VKHIRQEFDDYFDLCVAGYPGGHPEANSYIDDLKHLKEKVSAGANFVITQLFFRTETFLK
FLMDCQAIGISCPVVPGIFPIQGYHSLRQLVKLSKLVVPQEIKDVIEPIKDNDAAIRNYG
IELAVKMCRELLESGLVHGLHFYTLNREVATMEILRRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSAREELL
KMWGEELTCEQSVYEVFRCYIAGEANRNGHKVTCLPWNDDPLAAETNLMKDELVKVNRRG
ILTINSQPNINGKPSTDPIVGWGPEGGYVFQKAYLEFFTSAENIKALLTVLKKYGQRVNY
HIVNVKGENVTNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFTLWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLESCLWQVLEDTYEQLNSPGEEAKTSGF
>A0A7V8GAG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAARQQLYARKPEFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRETVRAQLSELKAMGVKRLVALRGDLPSGYGAGGEFQYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFVAKVKAGADSAITQYFFSADAYFRFVDE
ARALGIDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIKAFGLDVV
TDLCARLREGGVPALHFYTMNQSAATLAVLERLD
>I4CF25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1)|TrEMBL
MSVECKTNSKLEKILRSGQFAVTGECGPPRGADPEVIRKKCQLLKNNADAFNITDNQTSV
VRMSSIASAVIMMQEGMEPVMQMVCRDRNRIAMQSDILGGAALGINNMLCLSGDHQKFGD
HPSAKNVFDLDSIQLIQTVRGMRDNGKFLGGDEIKGVPKLFIGAAENPFADPFEIRVPRL
AKKVAAGVEFIQTQCIFNVKKFGEWMKGVVDRGLHEQVFVLGGVTPFKSFGMARYMANNV
PGMDVPDELLKRMKDTPKEKQAEEGITIAVETIQQLREMKGIAGVHIMAIEWEEKVGEIA
QKAGLLPRPVV
>A0A419EUV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Abyssubacteria bacterium SURF_17|TrEMBL
MKAGSNLERVLTEGNFAVTAELGPPKSADVETVHKKADILKGKVDAVNITDNQTAIVRMS
SIGAAKLVLDKGLEPVVQMVCRDRNRIAMQSDILGAYALGLKNLLCLTGDHQKFGNHPTA
KNVFDLDSLQLLQMFKRMRDDKVFQCGEEVRNSKKAPIVEPRLFLGAAENPFAHPYEFRA
IRLKKKVNAGADFIQTQLIFDVPRFKEWMKEVVGMGLHEKVFILAGVMPIKSPRVIEYMK
ANVAGLSIPDALIQRMKGASDPKEEGVTFVVEMINEVRQIEGVRGVHIMAVEWEEIVPTI
VERAGLLPRP
>A0A7S0LSY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccolithus braarudii|TrEMBL
ESFTTMPAPGPSLEIFVPRLPAGVDELLRERLPQLCMACPPVISVSGAEEHALQLALKLV
ASAFAPRVQLQLTSGLTREAAGSVLQRACDGGISDILLIPGARSHGSFDSVLELVQFVVA
HSGSMFVAVSGFPRGTKGELGMYTKDVSLASQHIAAGAQMIVCGPIFDVNHFVQYEGDIR
RAGVAKTVPVQPMLVPFNAFGGCAAMKRAARALQWSPPKDMQAELDKFGADPKGKAFSAF
ADSHFRSLYAEIAQRCPLVTPHVVTLNASVAVDALRTVGAISQANIATPTGGSSAVATPL
CIFCSAGEAGLQIARLVHERVCPAGSPPPASLNELTIEDLKQCAIPAVFVVEVEADFGAG
ADVRKLMRALKAQADVGPLIGVRVAVLTLAHSVCAFSSASAGKAKFAAGENLLRALTAAG
ATALAEVGGTEVELDDVDVSVVPWAQKVREAAGITEACQKIGGPSVV
>A0A5J4K8R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermogemmatispora aurantia|TrEMBL
MGTLLYARGIPYEQCFDLLNVTRPELIQGIHREYISAGAQIIETNTFGANRLRLAAYNLE
DRVREINFQGVRRAIEAREIVGLPVFIAGAVGPSGQPLQAPESGRLSEVRAAFREQIEAL
QEGGAELLILETFTSLAELRQAILAAQEVGGLPIVAQVSFYEDGRTLSGQSAASVARELY
ELGVDVMGANCCVGPAMTLEALQGMIGALDEEIQAAAQQGKRPPLFSAQPNAGLPTRLGN
RFFYVSTPDYFADYALRFAQAGVRLIGGCCGTTPRHIEAMRKALDAHYGRGVGAAGQKEK
EEAGQQNGLSASAQGQEGSRTASVVVPGRGGHRPVIGTLPEEEVILPQEGSKTRLQQKLE
AGEFVISVELDPPMGLNPSKILAGAAQLQRDGVDCINIADSPLARVRMSCIALARLIQDH
LGMETIIHFTTRDRNLMALQAELLGAHALGLRNILALTGDPLRVGDYPNTTGVWDVDSVG
LIRILRGMNEGHDAAGGSIGAKASFHIGAALNLNVSEEEAEREIEKYYRKLEAGAHFIMT
QPIYELAPLERFLKRVGKPPVPVILGCIPLHSWRHAEFLHNEVAGVTIPERVRERMRAAG
DQGTEEGLRLAQELLMEARDLVQGVYLLPSYRRYDIVGRLTRLLREAPANA
>A0A1Y6LUQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymoseptoria tritici ST99CH_1A5|TrEMBL
MDKITDKIAALPPNANYFSLEFFPPKTQQGFSNLNARLSRMAHSLRPLFVNVTWGAGGST
SAKSLALAEVTQRELGLTTCLHLTCTNMSRKLIDEALEQAKVLGVRNILALRGDPPRSDE
YRDNSLPNADEDDSNKDFTWAEDLVRYIRKQYGNYFCVGVAGYPEGHSDQSCPEHQSMEH
DLPFLVEKMKAGANFIMTQLFYDVEAYERFERRLREHESGAFKTVPLIPGLMPVQSYQIL
RRTTKLSHAALPEEMLKRLHAVKGDDEAVKRVGVDILSEMVEGMKSRKGNGPQGFHFYTL
NLEKVVAQIVERTGLIPPEEKKDENAVADDEVGDFVLVDKDVKQKQRRRKSSMANSQSRN
RVIVARTRASSNSSTRTSAAHEVPDDEAGIPREKINSRSNTLAISEGDGALGREATWDDF
PNGRFGDARSPAYGEIDGYGVSLHVSVPDAKRLWGEPKTIEDISTSFRRHLSGEIEAIPW
SEEPLQNETLTIKDQLQSLINRGWWTVASQPAVNGVRSTDPVHGWGPKNGFVFQKPFVEF
FIPASDWSALQGKLVEHPQITYFAGNAKGDFVSSGEDTVNPVTWGTFAGKEIITPTIIEA
VSFKAWCEEAFGIWAEWQRVYKPGSESSRLLERIRKEYWLVSVIHHGFLEEGALWKDLLE
A
>A0A2A4L5R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. 110|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
HKIPSIVHLPCIHSSKEKIISILQECKERQLDKFLALRGDVCNDLEKSKDFSYASDLISF
IRKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKKQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A4Y6AH72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcus xanthus|TrEMBL
MKIRNRLNPSDPCFSFEFFPPRTDEGEANLLKALEDLATLQPGFVSVTEGAGGSTRAKTV
ELVLRIKQETGIEAMAHLTCGGHSPAELRTVLERLSAAKVDNILVLRGDPPKGQTVFEPA
PGGFRYASEMARFIREEDFNFCLGGACYPEGHVETPSRDDDLRHLKAKVDAGLDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQIQRFTRLCGATVPMRLALQLERVKD
NPEAMAQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRARS
>E5VFN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. 4_1_36|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSIIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIREVAKQIY
>A0A0R2WHT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter sp. BACL10 MAG-120419-bin15|TrEMBL
MSIIPRVSFEFFPPKDIEASFRLWDTVQMLAPFQPGFVSVTYGAGGSTRALTHQAVTAIG
RKAGLNVAAHLTCVAAPREETLDIARAYHAAGVRDIVALRGDPPKGKSGFSPSNGGFASS
VELIKALAQTGDFNLRVAAYPEVHPDSQGAARDLDWLKAKIDAGATSAITQFFFKADTFL
RFRDRVLAAGIDFPIIPGILPVENWAGVKAFAKRAGSLIPPVLDAAFSVAARDGREELLS
LTHCTQLCDQLLSEGVEDLHFYTLNRPQLTRDTCLALGLKAKSTLQMVA
>A8G0M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sediminis (strain HAW-EB3)|TrEMBL
MGFHHAQHATSLNQSLAELNGDINVSFEFFPPATPEMEKILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETDLVAAPHLTLVDASDEELKELAKHYWNSGIRDIVALRGD
LPEGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDALNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFKQLKRFAGMTNVSIPGWLHKQFE
GLDDDPTTRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>M1C550|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solanum tuberosum|TrEMBL
MKVIEKIQESVKDDRVVFSFEFFPPKTEDGVDNLFERMERMVSHNPSFCDITWGAGGSTA
DLTLEISNRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPATGLATLETYENELAYLK
QKVDAGADLIVTQLFYDTDNFLKFIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKIMA
SGIKTLHLYTLNMEKSALAILMNLGLIEESKISRPLPWRRPTNVFRIKEDVRPIFWANRP
KSYISRTIGWDEFPHGRWGNAKNPSYGALSDYQFMRARSRDKKLQEEWAIALNSVEDIYE
RFMNYCLGKLRSCPWSELDGLQAETKIIDDHLGNINSKGFLTINSQPSVNGAKSDAPLVG
WGGPGGFVYQKAYLEFFCSREKLNAVIEKCMAFPFLTYMAVNKKGNWMSNVNQVDVNAVT
WGVFPAKEIVQPTVVDPASFMVWKDEAFEIWSRGWAQLYPENDPSRTLLEQVQNSYFLVS
LVDNDYINGDLFAIFKDMIWN
>A0A158LUE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii NIPH 190|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KKAKSFLIKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQVGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEITRFSCQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A8B5QIF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. wls712|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A2E4HI08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagaceae bacterium|TrEMBL
MTKVSDHITQAIAAEKTAFSFEILPPLKGQNIDTIFANIDPLMEFAPPFINVTYHREEYI
YKEHPDGLLEKKVVRKRPGTVGICAAIQNKYDVDAVPHVLCGGFTKEDTENFLIDMDFLG
IENVMALRGDAVKSEIYYKPNKDGNVYAQDLVAQIMDLNQGIYLDDDLQNSSATNFCVGV
AGYPEKHLEAPSVESDIHFLKKKVEAGACYVVTQMFFDNQKYFEFVDKARAAGITKPIIP
GIKPIATRKQLNMIPQRFNVDLPDELVREVIKCDTTQEIRQVGIEWAIAQSKELMAAGVP
VIHYYSMGKSDNIQKIASAIF
>A0A2S3XW48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ZL-24|TrEMBL
MALGTASTRTDHARTVRDMLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCANLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A1M7HNP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas subglaciescola|TrEMBL
MSSQEHPLGISFEFFPPATDVGRGKLLQARDALATRQPRFFSVTYGAGGSTQERTRAAVR
AVGERGITTAPHLSCIGSEKAQLRDLLAQYREEGIDSLVALRGDMPSGMASLGELRYGNE
LVEFIRDETGDHFDIAVAAYPESHPQAPNLDRDVENFARKMHAGANMAITQYFFTADAYF
RFVDKARALGVEKPIIPGIMPIINYTKLARFSDACGAEIPRWIRKQLESYGDDSDAISQF
GTEVVTNLCQRLLDGGAPGLHFYTLNQSTPVLKIVDNLTD
>A0A0V0ZIK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella patagoniensis|TrEMBL
MPALLMPSVPKGMSNIFVITYGLLNNMNKKGNFKVAKVGNPSQQTDFGVYFEEDSFLSLM
ASLEAVELKATRHDLNSAAKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTTEGLIN
LLKRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCILNFCLLDTMLHITSVQYDE
KTVLFNLERAKKIGIRNILALRGDISDDANVTTTDFQYACQLVRFIRSHYGDYFTICVAG
LYLLYAKVDAGADFIITQLFFNEMHYFKFVGDCRKIGIVVPIIPGILPIQSYQSIMKIVQ
LSKIVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRKLLNREHHVVPGLHFYTLNQEKS
ILEQIGFWKKAPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYLCRTRDWKQFPHSRWG
DVGIEAFGDLKHYLFSCIDQMDDSCALDMWDKELSTLEHVRDIFCNFIARTPNRHGHSVR
RLPWNENHLDPAADMLKNELIYYNSNGILTINCQAAVNGLPSSDPIFGWGEANGYIYQKG
YLEFFASSTCTTILLNHVQNFPSINYHAINFDGSFETFNYDEDATVALTWGVFVGQEIVQ
PTVANAASFRVWKDEAFDLWQRWAGLYESGSIGRKLLQRIHDDYRLITLIDNDYPQPCSL
SALLRAVISDYWGKKLDDG
>A0A4Q1JNU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylomarina salipaludis|TrEMBL
MKVIDHINQAIENKTTHFSFELLPPRKGNSIYKVFNTIDKLREFDPKYINITSHCDEVIF
AEAENGTFQKLLINKRPGTVAVAAAIKNKYKITVVPHVICQGFTPEETENALIDLNFLDI
QDLLLLRGDSSRRHEFSTRESGHNYAIDLIEQVNQVNRGEYLDGTHTEAFETPFSYGVAG
YPEKHEEAPNLDSDIYYLKKKVDAGAEYIVTQMFFDNQKFFDFEKKIRAAGITVPLIPGI
KPISALSQLNLLPQVFKVDIPEALAAEVRKCKTNEQVQALGTEWAIHQSRELVKHAVPSL
HFYSFMASNCVRDIAKAIF
>I7FNS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)|TrEMBL
MTPSGADPQVPVCPKRMTYGPCGGVRPDGRCEMRSGPCIFDDLVPWGGPVATRPPVRAPL
VLTDFSCAPFDEQDVVRTAGVLAGSCDAVLVGEHQNKPDFPPTLMGRLLLDALTGSGVTP
WITLSCRDRNRVVLEQELRGLRSIGADTVMCVTGDGRGYDVRPDVTQTFDLDGPRLVALA
ASLDMVAAVPETPTAPPVNARPRRLVEKQKAGAGIAVLNHVPYPHTVARFMESGRAAGLT
IPVIAAVAVFTDTASAAVLQGLPGLELDPAVTQRVLGAADPVEAGIEAAVEEARALLSID
GIEGVNISGSASASGGGAAIKAEVGRRVKNLCVDRTRGEAP
>A0A562YFA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Seonamhaeicola sp. W255|TrEMBL
MKVTDHIKEAKGKTLFSFEVIPPKKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYID
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKDEPYFKPVKGGHAYACELVEQIANLNRGQYLHDDVEVEHYSDFCIGVAGY
PEKHMEAPSLQTDLKRLKQKVDAGADYVVTQMFFDNQKYFDFVEKARDMGITIPIIPGIK
PIAVKRHLQLLPQVFKIDLPQDLIDAVETCKDNKAVRQVGIEFAIQQSKELKAAGVPVLH
YYSMGKSDNIKAIASALF
>A0A1E1G5L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas chlororaphis subsp. aurantiaca|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQTFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>E4URV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893)|TrEMBL
MEKISDKINALPQDAHYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEETKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFNYAVDLVRYIRKKYGDYFCIGVAGYPEGHADESHPEVQDPLKDLPYL
IEKTQAGADFIMTQLTYDIEAYKKYEALLRNHESGTFKTIPIIPGLMPIQSYHTLTRVTK
LSHAKIPPEVLAKVEACKADDEAVKQVGVDIVSELVEDIKKIATPGHRGFHFYTLNLEKS
VSFILERCKLIPPSSEASSDSELDFESAVYAASGASNGVVTPDGRSTNVSRMRACSMNSQ
PHNRVIVDRLTRASDRSERSSTVHETSAQTAGYPALNPPTRNTALQISEGLGSLGREATW
DDFPNGRWGDARSPAFGEIDGYGPSLHVTAQVARKLWGTPTSRDDISNIFKRLLSGELHA
VPWSEGGAGEEGGLNPETATIKTELLKLVERQGWWTLASQPAVNGVRNDHPVFGWGPKGE
GFVFQKAFVEFFCPGEDFHAKLKPLLQSYGHDEFAWFATNSKGDFESSTSTETSTPSPPD
PAEVPFDADPLTELDNGSVNAVTWGVFRNKEIVTPTIIEAVSFRAWGEEAFGIWEEWRRV
FPRGSASEKLIREVKDNVWLVCVVGQNFGAGGEVGKESNDEDGKLLWKVLAGEQTK
>A0A4D6Y4T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola subsp. Rhopalosiphum padi|TrEMBL
MNFLNQYHRDIIKKKLENLNDTIQCSFEFFPPKSLDAEKKLFSSVLKLSQLKPIFFSVTY
GANSGEREKTYNIVKTIHEQTGITTAPHLTCVDATLSELKEIAKFYWKNGIRSIVALRGD
ALKKSYQHKIYALDLVLLLKKIADFDISVAAYPEIHPEAKNAQSDILNLKKKVDAGANRA
ITQFFFNIESYLRFRDNCIKNNINIEIIPGILPIYNFAQLKKFSSMTNVSIPKWMFEMFN
GLDKDLVTQKIIGANIVIDMVKNLSYEGVKNFHFYTLNQADVIYSICHMFGFQN
>A0A1H0MUZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus singaporensis|TrEMBL
MSFQKRLASHEFAVLAEIHTPKGINISRLINDARRLKGRIDAVIVPDMENGIMRMSALAG
GVLLQQQGVETIMHMYCRDRNRMALQGDALAAHVLGIQNIIVADSADMSESDHSDAQAVS
DLNETDLIKALKTLQKGKDLSGFDLDGAPDFTIGCTLAPFSSDQELNQALEQARAKIEAG
ARYIITPPVFDIASCLPALEKIKTLGVPVIATVFLLKSLAIAQYIANSEPGANITDELIR
RIRKSSDREQEGIAIAGENIIALKDKVQGVVIQTLGWEHKLPEILDVAGI
>I3XUC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurospirillum barnesii (strain ATCC 700032 / DSM 10660 / SES-3)|TrEMBL
MLEPFIEKLKYESFLSLETTPIHEPTFEPMIEKIAHFGLDKHVDGFSTTDNPLARLKYNA
LFGALKLQNRFNKPVIATMSMRDRNKLALQSDLLGANENDLRAILCLTGDPSSASDQPSL
KGVFEGNSTLLMDIIQCFNAGMDYSGKPFKTQPHPIYPFAVCNAHSNTPRHLMKKIATKI
SHGAVGIISQPVYSVDNASMLLELLKEAKKELGKEDNEAQMILGFFPIVKLRTAQFLSAH
VPGVNVPNFWMEKLARAKKISEEEEKKVGFELSLQTFHALKKVHPKIHMMSANNFELVAD
LLKA
>A0A7U4DI96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A)|TrEMBL
MKNYSQYHQDIMNQKLENIRNNIQCSFEFFPPKNSFLEENLWSTVNRLSLLKPKFFSVTY
GANTGEREKTYDTVQKIYKKTGIITAAHLTCIDSTPHKLKEIAYNYWNSGIKSIVALRGD
TLEKDYRHTMYAVDLVLLLKKIADFDISVAAYPELHPESKNVKSDILNLKKKVDAGASRA
ITQFFFNIESYLRFRDNCIKNKINIDIIPGILPVCNFQKLKRFSSMTNVKVPKWMLDMFN
GLDDDIFTQKIIGSSIAIDMVKKLSCEGVKNFHFYTLNQSDITYSICHILGL
>A0A841XAA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEALTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVAEQIISQN
>A0A849QT85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinaceae archaeon|TrEMBL
MQSTFGEKLNSNKFIITAEISPPKGVNTSAALEDAQILKGLVDALNITDNQRAVMRMSPL
ALGKLLLNEGHEVIMQMTCRDRNRLAIQSDILGAAALGIQNICLMSGDYTTNGDHPGAKP
VYDLDSVQLLSIAQKMKNGFDFSGNELEGAPELVVGAVSNTDPSQPMQMMKLEKKVKMGA
QFIQTQAVYDIGQFEEFMDSVGHLAVPVLAGLIPLKSANAARFMNKNIPGVKVGDELIAR
MEHADDPVHEGLMICAETIGMLKKICRGVHIMPIGQHLNTPKLLEMAGLSVK
>A0A7X1DRN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVTEQIISQN
>A0A151ER28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon SG8-52-3|TrEMBL
MDFRSNLNKVLSEGKFAVTAEIGPPKGSDANVIIKKAENLIGCADAFNITDNQTAVVRLS
SLSGCSILLKMNLEPIMQISCRDRNRIALQSDVLGASAIGVRNILFITGDHQLFGNHPDA
KGVYDLDSIQLIQIVKNMRDEGIFQSGDRIISGNPEIYIGGVANPFADPFNYRVDRLEKK
IDAGSDFIQTQSVFNLDKFNIWMDEVRSRGLDTKVHILAGITPLKSIKMTERMKFNVPGV
DIPDHIYDKMKKAEDPKKEGYNIAYDLICEVKKIKGVHGIHITALFWEEIISKLVKETGL
YPRPI
>A0A7G6U7X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tardiphaga robiniae|TrEMBL
MTEINPATPTKLPNISFEFFPPKTEEMDRTLWDTIERLAPLNPSFVSVTYGAGGSTRERT
HATIVRLLKETALTPAAHLTCVGAPKNEIDDVVTRYHEAGVRHIVALRGDPTTGIGTEYI
PHPDGYKTSADLVASIRNRYPDIDVTVSAYPEKHPESADFDADIDTLKAKVDAGATRAIT
QVFFDNDLYFRYLDKVRSRGIDIPVLPGIMPMHNFKQARAFVTRAGTTVPDWLAAKFDGL
DNDAETRKLVATTVAAGQVQKLAKQGVSDFHFYTMNRADLVFAISHLLGFRPNGAQKAA
>A0A7J7HEQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Camellia sinensis|TrEMBL
MKVIEKMREAEKADKVVFSFEFFPPKTEDGVENLFERMERMVIHNPSFCDITWGAGGSTA
DLTLEISNRMQNMVCVETMMHLTCTNMPVEKIDHALDSIKSNGIQNVLALRGDPPHGQDK
FVQVQGGFACALDLVKHIRSKYGDYFGITVAGYPEGHPDVIQSDGLATPEAYQNDLEYLK
RKVDAGADLIITQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFIRMTGFCRTK
IPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKIMANGIKTLHIYTLNMEKSALAILMNL
GLIEETKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWEQYPHGRWGYSHNA
SYGALTDHQFMRPRARDKKLHDEWAVPLKNVEDIHEKFWKYCLGKLRSSPWSELDGLQPE
TKIINEQLVNMNSKGFLTINSQPAVNGAKSDSPSIGWGGAGGYVYQKAYVEFFCSKDKLN
ALVEKCNAFPYVTYMAVNKDGIWISNVSQTDVNAVTWGVFPGKEIIQPTVVDPSSFMVWK
DEAFEIWSRGWAQLYPEADPSRNLLEEVQSSYFLVSLVDNDYISGDLFAVFKDF
>A0A1F4DJG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_63_13|TrEMBL
MVEESTNTNNPPAERVPGALEQACKSGRFVVTAELSPPDSADPQDQLRRATAFRDMVDAV
NVTDGAGANCHMSSLAASSLLTAAGFDSVFQLACRDRNRIAMQGDILGAAALGVRNLLAV
TGDGVASGDHPQARPVFDLDSVSLLRIARGMRDRGEFASGRRLSVRPDLFLGATINPFAP
PFEERIINFAKKIAAGAQFVQTQYCFDLAMFETFMREVRSRGLNQRCHILAGVGPLPSLR
TARWMLAHVPGVHIPEQVLHRLEQAADQKREGVRICVELIRALRGIEGIAGVHIMAHRNE
HLVPDILRESGLTEERGESSAQRDAT
>A0A085BNF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. FH1|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFNPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEQSKGGHKYASDLVKQIHDLGTGKYLHEEIVQCEENSSFCIGVAG
YPEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKFFDFVKQAREIGIDVPIIPGI
KPIATKGHLQMLPQVFKIDLPENLISEVLKCKTNSDVREVGIEWAINQCKELLDFGIPVL
HFYSMGKSDNILKIGREVF
>A0A3N4IMI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ascobolus immersus RN42|TrEMBL
MGKITDHLAALGPNSTYFSLEVFPPKTDNVPPAHLLPVPPGTLNLHARLERMSHALHPLF
INVTWGAGGSTASKSLQLATTIQRDLHLTTCLHLTCTNMSRSILDDALAAAKEAGIRNIL
ALRGDPPRAEEYGVLPEEEAEFVWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEGTAPDIQ
DPLHDLPYLVTKVEAGADFIMTQLFYDVDKYIAFEKLLRSQDSLKDIPIIPGLMPIQSYQ
ILMRTTKLSHATIPDAVMDRIEAVKGDDEKVKEVGIDVVSGIVERLKSETGLARGPRGFH
FYTLNLEKAVALIVERTGLIPDVPKKVIVSDVTDPHATAVVEMNNRALVESGQPRIPEYE
AVDSEVIKGGKKAELRTQEIALAITEGQGTLGREAIWDDFPNGRFGDPNSPAFGQIDGYG
PSLHVTRTEATSLWGYPVDKTDITTLFTRNLLGTLRAIPWSEQELSAETKLIQPHLLKMN
EKGWWTVASQPDVPGVKSDHEVFGWGPKKGWVFQKAFVEFFIDREEWEEVRRVLDGLEDV
SYYAADAKGNFTQNASASPGSMNSVTWGCFPGKEIVSTTIIEEQSFQSWAEEAFGIWKEW
AYVFPPKSATREFLFKTVEETVLVNVICHDYMTPGRLWEILGV
>J3DPX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM78|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLSQYKAAGIQRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDINNFVRKANAGADSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1I7LKI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia namucuonensis|TrEMBL
METPNFSIEFFPPKTAEGAEKLRATRAKLSELHPKYFSVTFGAGGTTQRGTLDTVREILA
AGEDAAPHLSCVGGTRESLRAILAEFKASGIKRVVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQAKSPRDDLQAFVRKVNAGADAAITQYFYNADAYFQFVE
QARKAGVTVPIVPGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKEFGLDV
VTGLAQRLLAGGAPGLHFYSMNQAAPTTALWQRLV
>A0A5F1I7Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E4385|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGD
LPTGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2H3C294|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armillaria solidipes|TrEMBL
MKISQKIQQSTKEDKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTTEMVKTCQGIIGIETCMHLTCTNMPKEKVDIALREAKNSGCRNVLALRGDPPMGKED
WEAVEGGFVHGIDLVTHIRREYGDYFDVAVAGFPQHQLLPPEERDQELKYLKAKVDAGVS
FIFTQMFYDVEVFVAWVKAVRAAGITIPIVPGIAPIQTWNGFQRATSLAKTIIPQSFLEA
LEPYKNNDEKVREIGTKLVADMCRRILNEDIGIRGLHFYTMNLEKGTKMLLQELNLVPRV
ETIKPLPWRQCLTPSRRKETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDAIKLWGEPKSLEDVTTLFARFCKGTLSALPWSDQAPAIETSVIANQLA
QMNGLGFFTINSQPAVDGVRSDDKVFGWGPSNGYVYQKAYLEFFVQPALLSLLLSHIERD
SNITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGQQ
WAKVYDAESPSRKVISDLMDTCFLVNVVHNDFHDPDAIFKPFFRAGAEYKASLLNGNGNA
N
>A0A1L7GD27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TN58|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMADWVAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
SDVKERMLAVKHDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A550K965|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycocaulis profundi|TrEMBL
MSLSANTTGALPSISFEFFPPKNEAMEERLWDSISRLEPMDPGYVSVTYGAGGSTRDRTH
RTVRRILQETGLSPAAHLTCVNATRAEIDEVIADYKTAGIRHIVALRGDPPEGIGERYEP
HPGGYANAAELAEGISRIGGFEISVGCYPEKHPESASYDHDIDLLKRKIDNGATRAITQF
FFEPDVYFRYLDRVRAAGIDIPIVPGVMLQANFKGLKRMAGMCGSVIPEWMDELYEGLDD
DPRTRELITANVAAELCQKLSEGGADHFHFYTLNRAELALSTCRLLGVKPQEAAA
>A0A1F4S2B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-1 bacterium RIFOXYB2_FULL_36_35|TrEMBL
MKVVDIFEKDKLTLSFEFFPPKTEDQERNLFYVISELKNFNPDFVSVTYGAMGTTRDKTF
LWSKKIKHELKIEPVVHLTCVYADKDTVEKQVRELKKYGIENILALRGDPPIEDIYIPPK
NGFLYAKDLVSFVKEIACDFCVGVAGFPEGHCSISDLSVDTNYLKEKIESGAEYVITQMF
FDNRYFFDFKERCEKKEISVPIIPGIMPITNVGQIKKMTQICGATIPKELLNKIEKHSSD
YASVMEIGVEHAIKQTLELVKNNVLGLHFFVMNQSGPVSKVLSAL
>I4EU10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter marinus|TrEMBL
MSPLADDLTAPAGPREGCPKRMVFGPCGGVRDDGRCEVAEHACVFLAPPLPRWTGPTLPA
PAPRPGGLLDRARTRPVVLADLTVAPFDPASVRSVVGTLAPVSDGLLVGEHQGRPDLPPT
LMAQEVLAAGGRPWTTLACRDRNRLVLEQELAGLAAVGVDGVLCVTGDGRRAGARPEVTS
VFDLDGTRLTALATALGLSAAVAESPDAPPVPQRPARVAQKQRAGAQLCVLNHVGSAARL
TEFLAAARAAGATLPFVAAVAVYTDERSARVLQRFPGLHLDDDQVERVLTAPDTVAAGIE
AAVAEARALLAVPGVVGVNLSGLASAHGEETAAAVKAEVATRIREGVA
>A0A4Q2DFN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candolleomyces aberdarensis|TrEMBL
MQEGLIDEVLKSVKFRGIQNILALRGDPPRGKEEWIPSDPRFTHAIDLVRYIRSVPEYSS
HFCIGVAAYPDGHPDSTTDEDAELDVLKTKIDAGADFIVTQLFYDVDRFLNWVKKVRAKG
ELVLDSSITVPIIPGIMPIQTYGTFARLTKLCGTKVPAKLEDELAPLKHDDSLVKDYGVK
YAIEMLHRISTECEGEIKGFHFCTLNLEKSVQRVLEGLHWTGATSEIHNKLIADIPDPST
ERPQDTGLLITPTSASNEATSGLVSRTKSTTEAGKGELNNAASWDDFPNGRFGDFKSPAF
GNQDPWGGSGMMHSDVHPQWGLPRTVDDLTRMFLGYLRSEISTTPFSETPLCPESVTILP
HLEKLTKRGWWTVGSQPGVDGLPSADEIFGWGPKSGWVFQKAFVEFFCDGGDARAIEKLI
DEEGKGWVHYFMANSKGEVRSNVPQDGRNAVTWGIFPASEILQSTIIERESFLNWKEEAF
SIWTSWASFYRPDSPERQLLQQVADERWLVSIVHHDYKNTDALWTFLFDTTFHLPHLPAS
ALCLSLMTFVYRGLTRKLVIAFDLGTTFSGVSYRQAIDFEWFPAHEQVNSGSKIPSIIYY
NEDGRVKAVGAEAMQQEIIDIAKEEGWEKAECMKSAVDVCSDFFRYLFNCTREYIQEAHA
NGSDLWESVKSDIDFVISHPNGWGGFQQAQLRQALAQAGLIEADEEPGNSRVSFITEGEA
SLHFALRHGLPPAVSENGEGVIIVDGGGGTIDISTYRKPKLKNNYEEIAVSEYYLSESEH
FDDIDHIVSCFDKTTKVWFSDDQQPQYIRFGSTRDNDPSHNIRFGQLKLQGSDVATFFQP
SIDCITETVEDICKTSTYPITHVVFVGGFSASEWLYKRLAAAVEPRNLQILRPQVHPNKA
VSDGAVSSYLNGIVTARIARHSYGVLRNVEYDANDSDHLNRVDSLLYRPSGRKLVPNAFK
VMLAKGTKVSDETEVAVKMWKEVGSDQKSKLENVPFTLYCYKAKRNAQPPKFFDQDSNGF
TKLCSVQADLSNLPLEPLPKGNGIEGEFYRVKYSVVLLFNSAELKAHIRWEENGVQQRTQ
ASVVFFDDS
>A0A0E1GI76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter fetus subsp. fetus 04/554|TrEMBL
MLKKKIKDNTPGILLYGLTPPKLNLTHEEAIIVAKKQLERLENRGIDGLVIYDLQDESNR
NKSERTFEFCGTIKPEIYHKEFLKLAYPAVIYKAVGNYTQDEFCRFLNDSGENLSVFVGA
SSKKDSPKLSLDMAYKLKKEQGRDITLGGICIPERHEKKGDEDLRVAGKTIKGCEFFITQ
AVYNLENAKRFLDDYSNLNIKKVPIIFTFTPCGSLKTLEFMRWLGISVPKQFENRLFKSD
DPLKASISLSLDMFEFLFKYGKAKGISIGANVESISTRKVEIEASVELVNGIKSIIS
>A0A7D4QMN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter mali|TrEMBL
MKITEHIQNAKGKTLFSFELIPPLKGQSIQGIYDAIDPLMEFKPPFIDVTTLREDYLYKE
HENGLLEKLSYRKRPGTIAICAAIMNKYHVDTVPHLLCGGFTKDETENGLFDLQFLGIDN
VLVLRGDARRGDASFIPTPNGHNYATDLLQQVVDMNNGVYLHEYNEDNLKTNFCVGIAGY
PEKHFEAPNMKTDFKYLKQKIDMGAEFIVTQMFFDNQKYFDFVNNCRANGISVPIIPGLK
PLANTKQLAGLAKTFHIDMPEDLCDAVAACKSEKEVKELGIEWTINQCKELIKFGVPVLH
FYTMSNAGPTKRIAEAIF
>A0A0M8WX83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL B-1140|TrEMBL
MTTFSFEFFPPKTDNGTRALWDTIRRVEALRPDFVSVTYGAGGSSRERTIDVTRRIAAET
TLRPVAHLTAVGHSTAELRRIIGQYADAGIRDVLALRGDPPGNPNAPWVPHPQGVTHAVE
LVELVRSLGGFTIGVAAFPERHPRSPDWDSEIRHFVAKCRAGADYAITQMFFDVEDYLRL
RDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSGAAFPEHLAHRLEAARDRPADGHAIGV
EHATAMARRLLAEGAPGLHYITLNRSTATLEIHHNVLGSTADSVPNARSTRVLVHD
>A0A545U536|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliikangiella coralliicola|TrEMBL
MGFNHAQQVEILNQNLFDLSGKVNVSFEFFPPNSAEMEKTLWNSVKRLEGLSPKFVSVTY
GANNSTRERTHRIISRIQQETDLVAVPHLTCIGASREELVEIAQEYWNSGIRHIVALRGD
LPDSDKVGQQADMYALDLVKLLKSVADFEISVAAYPEIHPEAPNPQFDLINLKRKVDAGA
SRAISQFFFDTETYLRYRDRCLASGIDVEIVPGILPVTNFKQLLRFSKMTNVTVPGWMHR
LYQGLDEDATTRNLIAANVAIEQVKVLAKEGVRDFHFYTLNRSDLTYAICHSLGVREKAF
EPQAIAV
>A0A514EYC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella electrica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAEDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A437M419|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovarius crocodyli|TrEMBL
MEKTAAPKETGTLDRWLSGPRIAALPNPQAMPVPKLSFEFFPPKSEKMEEQLWECIRRLE
PLGPRFVSVTYGAGGTTRSRTHSTVARIVRETSLTPAAHLTTVGATREEVKEVAREYWEA
GVRHIVALRGDPPAGATKYEPHPGGYAQAEDLVRGLREVGDFEISVGAYPETHPEAISAD
ADLDFLKRKIDAGATRAITQYFFDTEVYLRFIERCAKAGIKVPIVPGILPVTNYQQVVKF
SAMCGASVPAWMGHLFEGVDDDLDTRRMVSAVVAAEQVRLLQANGVDEFHIYTLNRADLA
YAIAHILGARPKA
>A0A2M9TT95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. L7|TrEMBL
MSKPAFSFEFFPAKTEQGGQKLLNTYDELNKLAPSYFSVTYGAGGSTRSRTLDIVQTLCA
RGDTDIAPHMSCIGDDKVEIAGLLDHYKALGIKRLVALRGDLPSGQIGMGELPFALDLVK
FIREHSGEHFRIEVAAYPEMHPQARSFEFDVDNLVNKYQAGANAAITQFFYNADSYLYLR
DTLERRGIDTVAQPLIAGIMPITNSSNLVRFADSCGADIPRYVRKRLADFGDDSKSIREF
GFDVVYRLCERLMSEGVPAMHFYSMNKVEPNKRLVEALGLSA
>A0A255YX24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sandarakinorhabdus cyanobacteriorum|TrEMBL
MQEAARAIGGPLYADLPGDLAVSFEFFPPKTPAMQDSLWQAVETLVPLGPRFFSVTYGAG
GSTRERTHATVARIVAETPTPAAAHLTCVNATAAELDAIADDYWAAGVRHIVALRGDPPG
GQARFEPVPGGHASAADLVKALKRRHDFEVSVSCYPEVHPEAASPAADLEALKAKIDAGA
SRAISQFFFEPDTYFRFRDAVAAAGLKVELVPGILPVSNFANLQKMAASCGTHLPDWMGR
LFAGLDDKPAARQLVAATVSAEMARRLYAGGVRHFHFYTLNRAELSYAICHLLGVRPVLE
AQ
>A0A1W1VZ08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermanaeromonas toyohensis ToBE|TrEMBL
MSWKSGSKLEKLLSQGHFVVTGEVGPPKHASPDGILHHAELLKDYVDAINLTDNQTAIVR
MSSIAAGVHVLRAGCEPIIQMTVRDRNRIALQSDLLGAYSLGIRNVLCLSGDHQSFGNHP
TAKNVHDIDSIQLIRIVKDLRDEKRFACGEEIKEHEPRFFIGAAANPFADPFEFRILRLE
KKINAGADFIQTQCIFDMERFERFMAMVRERGLHKKAYILAGVTPLKSARAARYMQQSVA
GMIVPEEIVARMEKAKDPKAEGVAICVEQIKHLRTIEGVAGIHIMAIMWEDIIPTIVKEA
GLYPRPQVD
>B8BVS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassiosira pseudonana|TrEMBL
MNGHTERQPDPKIIDLLQRDTEIAHVSLEYFPPRTDQGVKNLHARMDRMLVNTNALYTDM
TWGAGGSTADLSLELALHAHKTGHVSNMHLTCTNMEKDGDPVKAVHDALQQAYDGGIRNI
VALRGDPPEGEKEWTATEGGFSCALDLVKYIRKTFGDKFGISVAGYPEGHPNRISQLSEE
EDEDYKKEMDYLKEKVDAGGDFIITQMFFDAEVFKTFVNDCRTWGITCPVVPGLMCINAY
PGFKKMTKFCKTRVPKSLEERMDAIKDDADAVKKFGVEFGAEISRNLLDSGVKILHFYTL
NLEKVVYGITDELGITSGLIEKSEESDAKDMVAVGSAWARAGDTVKFSTGQGVVKEIKSD
GTAVVELDGKDVEFAKGSYEKVF
>A0A3D4C3Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabaena sp. UBA12330|TrEMBL
MPDTQSYSAFNNFRKASLTGEFLITAEVAPPKGGDMTHTIKMAATLKGRVHAVNITDGSR
AVMRMSSLVASAILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDNPQAKAVFDLEAVRLLQLIRNMNQGIDFNEKPLTDGKLDLFAGAAVDPQSRSWSGLQS
RFEKKIAAGAQFFQSQLITDFEILEKFMDKIACGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEEGMKIAAEQVQMARGLCQGVHIMAVKREDLIAPILDLAGV
EKVS
>A0A1U9VHU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|blood disease bacterium A2-HR MARDI|TrEMBL
MQDRQFRFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILNTYRENGIRRIVALRGDLPSGMGEIGEFRFANELVEF
IRHETNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLLRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>A0A2P8AHU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 111WW2|TrEMBL
MRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVRE
TQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPNADWIAHP
EGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTNFVDKCRAGADYAITQMFF
QPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASFPAELKERILTAKDDP
AAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPRA
>A0A3B9ZJE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MTFKEKIQALLGGQAGKFLISSEVGPPKGIEFKTILEDVELVRGRVDVINVTDLQSSVMR
LGSLAVSIRLKEKGFEPIFQVTCRDRNRLALQSDLLSAASFGIENVLALTGDHPKLGDHP
HAKAVFDIDSVQLIEVIRQLEKGTDMAGKKLEGALPKFCVGAVVNPGSEPLEPQLFKMEK
KIEAGAEFFQTQAVYDIKSFENFLSKTKHCKIPIIAGIVLLKSAGMAKYMNENVAGIFVP
DNFIKEMQETKDKQAKSIEIAARLIKELKPMCQGIHIMPIGWDKLVPKVLDAAGL
>A0A0G4QFZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus penneri|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTEEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASREELQHIAQDYWQSGIRHIVALRGD
LPDNTQKPDMYATDLVHLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFADLTNVKIPGWMHKMFD
GLDNDPETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPELVQA
>A0A5Q2VXM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudactinotalea sp. HY158|TrEMBL
MSTAGLFSVPGTTPRVSFELYPPRSPAAQERLTRTVAELAAARPDFFSVTYGAAGRTHAT
SRGLIRQILAETDVTPIAHLTCVGASREELRVTVEELLEDGVRDVLALRGDPPTGGAPWE
PHPRGLTRAAELVGLLREIESERFELAEGQPRPLSISVAAYPARTFQAAQGSVLAAPRDL
EALHAKQEAGADFAITQLFYSAPEYAAHVEAARAAGIRLPIVPGVIPLTDLARLQRLTQL
TGVPVPEALELRLSAARDADEQYRIGLAASIELVEELLAVGAPGLHLYTFNTSRAALDLL
RGAGLREPAPSTSAAHR
>A0A3G8GXM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus pauculus|TrEMBL
MTDRYYSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSTRENIRAILDAYRQGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFHIEVAAYPEYHPQARSPRHDLDNFARKVKAGANSAITQYFFNADAYFRFVD
DARAVGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKKLESFGDDKESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNTAAATKAIWQRLKL
>A0A0K6IIJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinomonas fungiae|TrEMBL
MFSLPPFSLETTGKSAHELASVADLFAAHTPVNIAFLGNESHAQRIQAAATIKSLGLEPT
PIISSRRLQSKEDFYHYVDPLVKQSHIKRLMVVGGDPKQPQGPYNDSIGLLKSDLLKSCE
LETVVIAGYPEGHPHIRSQQLIESLKWKVAFLKQQNVKVEITTQLAFCTESIVKWIETIR
SSGIHEPIRIGVPSSTRVKTLSYFAQQFGVEISAASLEKYAMDTTDETLEAKTDALYQEL
TQTIKRHGYENIYFHLYTLDGMVKSKAWLENFLRP
>A0A3D2F011|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium|TrEMBL
MASKLLFGVSMQVSFEFFPPRDNAGQNSLDNAVQQLQVWQPQFASMTYGAGGTSQQASFA
GAQKLLAQELATASHITCVGADRETVQATAKQFVAQGVDHFVALRGDSPNGPYVPHPQGY
AYANDLVAGLRDWFTGTISVAAYPEIHPQALSGAKDLAFLKAKMDAGADQIITQYCYDTD
TLLAFAENLQKAGITQPLLVGIMPIHDIAAVQRFSARCGATVPQSFGDRFAGLEQAQDKV
KLAIEIAAEQCRQLIDNGLDQFHFYTLNRSTLTAGVLASLEQPPVNLALSA
>A0A2E2IAE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium|TrEMBL
MTTLSFEFFPTQTDEGTSKLLAVRDELAAFDPEFFSVTYGAGGSTRDRTFAMVEAIQQRG
IAAAPHLSCVGDSTADLRDLLQRYQALGIKRIVTLRGDLPSGSGLASSELRYANELVEFI
RKETGDHFTLEVAAYPEMHPQASSFEKDLQNFVRKVKAGADSAITQYFFNADSYFHFVDR
VRAMGVDIPIIPGIMPITNYSKLARFSDSCGAEIPRWIRKQLEAYGDDSDSIVKFGEEVV
TDMCRRLLDGGAPGLHFYTLNQAKPSLAVWKNLV
>A0A2N6F0H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MTEISIELVPRNEASLRRELELVRDRFSSIERINIPDILRFDMRSWDACKIAGEYFPKTI
PHLRAIDFDPNAPLDIDAEITAKGIEAVLVISGDPPQDMSHKIYRTGALEMIRRLKRELP
DLKVYAGMDPYRSGIKEEIDYLRAKRDAGADAFFTQPFFDLRLMDIYQGFLQDFTIFWGV
SPVLTENSRNYWENKNNAIFPPDFVPTMEWNREFARKALEFARENGGNLYFMPIRTNIGD
YLEGIL
>A0A0B5CP47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria elongata subsp. glycolytica ATCC 29315|TrEMBL
MTSPSKKLSFEFFPTRTPEGRAKQVITRKQLRQFSPEFFSCTSGAGGSTRDGTMQTIGDI
LAEGTAAAPHLPCIGMTAAEIRELLDTYKEMGVRHIVALRGDIPSGMGAGTSGLRYANEL
VELIKNEYGSHFHIEIAAYPEYHPQARSAEDDLNHFVRKAKAGADSAITQYFYNADAYFR
FLDDVRGRGVDIPIIPGIMPIASFSKLVRFSDTCGAEIPRWLRLKLQSYADDSAAIKALA
LDVVTEMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>N9R3P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 1867|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKTVHQELQQLNPEFFSITYGAGGSTRERTLAAISDFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERITKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A6B8QKI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. PA16-9|TrEMBL
MSSHEHPLGISFEFFPPSTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTREVVR
AVGESGINTAPHLSCIGSEKAQLRDLLAQYREEGVESLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLEGGAPGLHFYTLNQAAPVLRIVDNLAG
>K0JL64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira pilosicoli WesB|TrEMBL
MNNNVENFIKKLENNDEYTFTLEISPQAKYDLSYIEEKINNSQIQNYVDAFVVTDSPFAN
IKISPILAAIQFQQKLKNNKPFIATQTMRDKNSIALQNDLIGANYFDIRMILAVTGDAVA
NGNQKQAKGVFEGNSNLLIDIIKNLNKSKSLGEFTFKEPLKPIYPFCVINSYAKNDDSLK
VRLAKKANSGVKAIFTQPIYEVERLEFLLKCIDELPLKEKPILVPGFFPVLTYKTAYFIY
YKLSGSYIPEKWLSKLKKASDKSEEEEKKTATELSSKLFEDMLKIHKKMHIMSLNNYEFV
VDLLKNI
>A0A6C2UAG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontiella desulfatans|TrEMBL
MKTILERMADQPLIFDGAMGTMIYSKGVFINTCYEHLCITNPKLVGGIHQEYADAGADVI
ETNSFGANRLKLQGHGLADQLEDINRASVRLARAAAGDAALVAGSVGPLLKSGQVFLESQ
AGELAEIFREQLAILADEGVDFFMLETFTHIQEAQLAAKVAKTLGIPVFVSMTVGIEGTT
EKGRKVEQLVQTLENDGNVDGIGLNCGVGPAAAYSNAERALPLTSKPMVVMANAGYPQEV
DGRMIYMASPEYFTEYAKRMIELGVRGVGGCCGTTPADIATAAKSIKSMTGVKQHVAISS
HTDQEAPKVDVVPMAEKCGFAAKLARGEKVTSVEITPPRSIDLKPMLAQCQTCKDAGIDA
INIPDGPRASARISPMVAALFVEREVGIETVLHYCCRDRNLIGMQSDLLGGYAGGLRNYL
IITGDPPKLGDYPDSTPVFDVDAVGLTQVVNNLNHGVDVGGNPINPPTGILIGVGANPCA
VEPERELQHYMNKIHAGAEYSITQPIFDPEALLRFMDAAAARGGTIPVVAGVWPLVSLRN
AEFLANEVPGVEIPDAILERMSHAKTKEDGRKLGIEIAREICEAIADRVAGYQVSAPFGI
VDLALQVLEN
>V9V7S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas monteilii SB3101|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSTERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSRQATPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPMWATRLGSQVLHKVEHAVKHPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTALLTERLIPCIELETRHRSSWPQWFQAQTP
RQLSPQPAPRTQPES
>A0A1M6WX56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerocolumna jejuensis DSM 15929|TrEMBL
MELREYLKEHKLITDGAMGTYYSRLLNNDNAVSEFGNLTEEATITAIHKGYIKAGAELIR
TNTFAANRQTLNQTGKEQKELIKKAYRLAQRAVAESAEEGQAKSRRVYIACNIGPIPENG
TRTEEDILLEYQDICDAFLEEGGDIFLFETFSDFYYLKSLVKYIKAKKPEAFLITDFCLN
KNGFTTKGISARSILETIEETKEIEAGGFNCGIGSGHMYQILKKLPLPEGKFIFAMPNAG
YPEQFQNRLLFMDNEGYFRENIQRICDLGIDAVGGCCGTTPDYIKNMAERLSLKETFRGN
RIVLSGIKEANVEVRPNEFYQTFQEKKKVVAVELDPPFDASDEAVIACANKLKGTGTDII
TLADSPMGRSRVDSVLMALKLRNETGLPVMPHICCRDKNVIAMRSMILGAYVSGIRNILI
VTGDPIPSEHRQSTTGVFDYNSIQLMSYVKEMNREHFKEEPIYYGGALNYGRGPIEKVIE
RMEKKIEAGASYFLTQPVFTEEDIRRLEEIKSKVRTRILCGIMPLVSYRNANFIKNEISG
IHVPDWVVEKYRPDMDREEAEWVGADIASQIIKDISPFADGYYFMLPFNRVSLMNKIVIR
>A0A7X8IF57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MLNSSILTKKQVFSFEVFPPKKDDGIDKIYKTLDELSDLKPDFISVTYGAGGSENSGKTL
EIAKRIKETCHVESVVHLPCLHLSKKEALMLLREFADNGIENLLVLRGDKIEGREPAGDF
FYASDLASFIQKTMPGQFYLLGACYPENHPDSKDVFEEITHLKTKVECGVTHLLSQLFFD
NEKFLKFTENCRLANINVPIEAGIMPVTNKAQIERMTSRCGVELPQKYKSMMEKYGTNDN
AILEAGIAYAINQIVELLTYGVDGIHLYTMNKPYIARRISEAVTTLLTEKST
>A0A7R6XEL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 113-3-9|TrEMBL
MTARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A2R4FPF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plantactinospora sp. BB1|TrEMBL
MALGLPSVLPDSRPAIGDLVRGPSPTFSFEFFPPKTEKGERLLWQAIRELESLRPSFVSV
TYGAGGSSRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRNVIGRLAGAGVRNVLAVR
GDPPGDPMGEWVQHPTGVLYAEELVRLVREAGDFSVGVAAFPYKHPRSPDIATDTRYFIQ
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILPGVMPVTQLSTIERSQQLSGAPF
PPALAAQFDRIADDPEAVRQLGIQQASEMCRRLLDEGVPGIHFITLNRSTATREVWQSLQ
AGVGV
>A0A7V4CUS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MKVTEHLDRSTDTLISFEIIPPKRGGDIRQLLTVLDDIVKYNPPFIDITSHAAEVVYEET
KNGEMKMKVKRKRPGTLGICALIQNKYNIDAVPHVLCSGFTREETEDFLIEIHYLGIDNV
LAIRGDESSYQKPIKFGRSVNEYGIDLIKQISDLNNGKYLEDGLLDAYPMNFCIGTSGYP
EKHFEAPNLITDIKYTKAKIEAGASYIVTQMFYDNKFYFDYVDKCRQEGINVPIIPGLKI
ITSRAHAHSIPKNFYIDIPAALVEELDKAKPEHTMEIGVEWTYHQVEELLNKKVPAIHFY
VMQNSKPIKMLMKKLGI
>A0A2K9K1C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. NC201|TrEMBL
MALTLQEKIIDPNQGVYLIGTTPPKIGTDPEQLKSIAAKLLGRLHEIEYDGVIIYDIQDE
SSRTQVPRPFPFKHTVDPCEYSQLIRELSHLDVITYKSVAQRDSEAFGDWLSSTKQQYGL
NNLVLVGSPSSQGDIKLPLSEAYKVLKHHQDDFFLGGVTIAERHASKRNEHERLIDKTEQ
GCQFFVSQAVYDAQATIDLITSYARTCKQQGQTPKRIILTFTPCGGEKTLQFMEWLGISV
PEATKWRMLDSENTLSESIRICRENLDQILKSCSHLDISLGLNIESLTNRKEEIDASINL
YRLLKATMELCLAEKQIA
>F7K170|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 2_1_58FAA|TrEMBL
MENEHKEDDIKYLKQKVDSGVDFLTTQMFFDNDIHYNFLYRIREAGITVPVLPGIMPITS
ARQMKRSCELSGTVFPRRFQAILDRFGDSPKAMEQAGIAYATDQIIDLLANGVKNIHIYS
MNRPEVAAAIMHNISEIIQC
>A0A252ATQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter indonesiensis|TrEMBL
MSLSRLSVELIPRTNEALLDDVARVKTLLPAADTLNIPDLMRFPLRSWDAAALVRPHFPS
VVPHVRAIDIAPDATLPGADQDGLKDVLVVHGDPPADLSHRTYPNSTESIIRRYKKEAPH
LRVYAAFDPYRRAPWRELEDVARKKEAGAEGFFTQPVFDLKLFDLCQEWLQNETVFWGLS
PVIGPKSRSYWETTNHVVFPKNFEPTLDANIYFAQTVLRTLSNQKGSVYLMPLRVKLDQY
LPPLLEALE
>A0A3C1SIF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MKITDIASQKKLLVSMEVFPPKKQDALDSVVSAAQELTQLKPDFISITYGAGGTTKVNTL
EISQKILSFGTPALSHLTCVGNTKESISSAIEQMKLHNIQNVLALRGDIPQGSTAEASLS
PDLRHASDLIPLLKEAGFCVGAACYPEGHPESDDRLQDLENMKYKVDAGVDFLTTQMFFD
NNMLYSYLYRLQSAGIHVPVFAGIMPVTNASQVSRMIKLSSAYVPAKLLAICDRFEKQPE
AMYQAGIAYVTDQIIDLISNGIKGIHIYTMNKPKVARDILNNISAIREAVNASQEK
>A0A4Q4ST00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria arborescens|TrEMBL
MHISQKLLQAREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLPWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDDALRDAYNAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDDVDELIDHLKEKVDAGGTF
IVTQMFYDTDLFLEWVKKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTRCNIPKDWTEAL
EPVKNDDVEVREVGKHLVAEMCRKLIDAGITHLHFYTMNLAQATRMVLEELDLLPDPESP
LEKPLPWRPSLALNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPMSIRDLSELFVRYMEGKLESLPWSEQPITTEAGSIQDDLIN
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEHISEIITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVIHNDFHATRGIFPIFDGLEVKDMDKPLVNPSVDLPSANGEETTKVVNGGSHTN
GTNGEQAEPHKEENPSLIDAAKAAAVEVTNGMRSLAMSN
>D4KRZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia intestinalis M50/1|TrEMBL
MRLTELLNTENVTISCELFPPKQGAQLDNYKKIVGDMAALKPAYMSVTYGATGGTSDYTV
ELANEVRNVNHIPALAHLTCASSTKEKVASVIQELKEKQIENVLALRGDIPQNADFPLPN
QYKHASELIYDIKSQGDFCIGGACYPEGHPESQTLEEDLIHLKEKVDAGCEFLTTQMFFD
NNILYNFMYKALKHGIDVPVVAGIMPITNANQVKRSIALSGSLVPRRFLAIVDRFGSDPA
AMKQAGIAYATDQIIDLIANGVNHVHIYTMNKPDVAGAILENLSDIYVRD
>A0A6N3WX40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris|TrEMBL
MSPDPPSRAATITDAYSLEVGAHDMAALTAAAPQIMRGSSMFIPYLPSQNDEARLAAAQR
VRALGFAPMPHLSARRIASRDALQAFVGRAVEDAGVERCLVIAGDAPSAVGPFSDSVSLI
ETGVFERSGIKTIGVAGHPEGHPSMPASAQWDVLERKCRSIAERGMAPLIVTQFAFDADT
VLTWLEALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACTSMLSKYGISLGKLFGTA
GPDRFVDRLTAGLSEVHGDVSLHFYPFGGIAQSVAWVEQYRHRSARPLAD
>R5QU64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprobacillus sp. CAG:235|TrEMBL
MKINELLKKRPTLSFEIFPPKNNENDITSIYATIDELAKMNPDFISVTYGANGSTSKNTC
KIASTIKNKYGIESVAHLTCMNNTKDEIKEILEELKENGIENVLSLRGDYPKDSDGINHG
DFKYASELNEFIEENFPNDFCLSGGCYPETHYEAKNFEEDLLNLKKKVDAGAKYLVTQIF
YDNQYYYRLVREARKIGIHIPILAGIMPAHNPKQLKNIAKMSNCSVPFDLAAMIDRFAGN
PKAGREVGLHYATYQIIDLMTHGVDGIHIYTMNKPEIAKEILKRTEYIRDEFFKD
>F9HGI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. oral taxon 056 str. F0418|TrEMBL
MTRHTPSLSFEVFPPNPAAGNEKIVKALREMQDIAPHFISVTASNNKFNIEETTVRLADF
IYNDLRIPTIAHLPAVYLTKEMVSTILHALDKVGVHNILALRGDIFPDAAPKNDFKYATD
LIEYIKEEAPHFDIIGACYPEGHPNSPDCVSDIKNLKKKVDAGCSSLVTQLFFDNERFYN
FQEKCVLAGIDVPIHAGIMPVLNRNQALRLLKTCENIELPRKFRAILDKYEHDPESLRSA
GLAYAIDQIVDLVTQDVAGIHLYTMNNAATAHHIYQATHTFFAK
>A0A5H7LI86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella moscow|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5V3UWF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKLEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1G0I9H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_43_28|TrEMBL
MTTLPLTISFEFFPPKSPQGAEQLYMTASALALYRPDFFSVTFGAGGSTRKGTLDTVTVL
KELTGIPVAPHLSCIGSTREELIETIRYYKAIAVKRIIALRGDRPSGMGNAGEFKYASEL
VSLIREETGDYFYIEVAAYPEIHPQAKSAMDDVLNLRRKFEAGANSAITQYFFNPDAYFY
FLDECANQGISIPIVPGIMPISQVSSLVRFSDVCGAEIPRWIRKRLESYGDDTASIKQFG
LEVVYDLCQRLMMGGAPGLHFYTLNKLEATQALLDLLNLKQMMQQKPTEVVELVKMDKRE
>A0A3D2HAN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionella sp|TrEMBL
MSISHISFEFFPPQTVEGVEKLTIAREKLATLNPEFFSVTFGAGGSTRDRTLETVTQIKV
EGFDAAPHLSCVGSTRDNIRAILKTYRDAGIRRIVALRGDLPSGMATAGEFQYANELVEF
IRTETGDHFHLEVAAYPEVHPQAKSARDDLINFKRKIDAGADSAITQYFYNADSYFHFVD
ECQKLGITAPVVPGIMPIVRYSQLARFSDACGAEIPRWMRKTMEGFGDDNESVQAFGRDI
VTAMCEKLLAGGAPGLHFYTLNQAAPCLAIVERLK
>A0A3G3GZL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAAYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLVDAGVPGLHFYTLNAAAATKTVCERLV
>A0A3M3FRS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. glycinea|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGTPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1I6XVG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium XBD2001|TrEMBL
MTIKEIFRQNEVTLSFEIFPPKTDAGFAAVEDCAHKIAALEPSFMSITYGAGGGTSANTA
KLAAKLQNEYNTDVLAHLTCVSSDRAFVRARLEEYQQLGIENIMALRGDLPKDGIVSSDF
THAIQLIQEIKECYPAACIGGACYPEGHVECERQSDDIRYLKEKVDAGLDFLTTQMFFDN
NILYNFLYRIREQEIKVPVVAGIMPITNKKQVARSVALSGATIPQRFRTMVDRFGDDPAK
MTQAGVIYATEQIIDLISNGVTHIHVYSMNKPEIAAGIQKSLSYIIDK
>A0A5B9FCM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. WL3|TrEMBL
MTKTERPIAKTSDLRISFEFFPPKSPDMDEQLWQTVEALQAYQPDFVSVTYGAGGTTREP
TLSTVKRLITETPLSTASHLTCVGATREEVRAVVEEFQAVGVRHFVALRGDPQGGVGTRY
APHPGGYVNAADLVSGLRDMGDFEISVSAYPERHPESENDVVDLDMLKQKVDAGATRALT
QFFFDNDIFERYLERVRAAGITIPIVPGIMPIQNLTQLKRFAAMCGASIPSFLDARFEGS
EGDPRARAAIAAEIAAEQIADLSRRGLQDFHIYTMNRAPLTIATLERLGVSTQTGNVSGA
AA
>A0A5E3WWQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peniophora sp. CBMAI 1063|TrEMBL
MKISKKVEKATKEDKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
ELTSELVKTCQGYIGIETCMHLTCTNMPKEKVDIALKEAKEAGCRNILALRGDPPMGKEE
WTSVEGGFEHGIDLVRHIRAEYGDHFDIAVAGFPQHMLLPEAEREQEIQWFKQKIDAGVD
FIFTQMFYDIDIFISWVKAIRAAGITIPIVPGIMPIQTWNGFQRATSLAKTHIPQTFLDA
LEPHKNNDEKVREIGTRLVADMCRKILAAPLGIRGLHFYTMNLERGSRMLLEELNLVPRV
ETLKPLPWRQSLTPSRRSETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGDLD
GYGASIKQTREDALRLWGHPASFAEVASLFRRFCTSELPALPWSDQAPSLETSVISTPLA
RMNALGFLTINSQPAVDGARSDDAVFGWGPANGYVYQKAYLEFFVRPQLLDVLISYLEKD
PSITYYVINKRGDLRTNNTQEGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELWRQ
WSHIYEPESSSRALITGLMDELMLVNVVHNDYKSQEAIFKPFFLAGEQYAATHPNDAVVL
PNETEHLLHNGDAIAHESGTA
>A0A073AY63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora rectivirgula|TrEMBL
MTAVVDRLNTGRTSFSVEFFPPRNEDEERLLWRAVREVEPLDPAFVSVTYGAGGSTRDRT
IRTTGRIANETTLTPMAHLTAVNHSVAELRNVIGWYAASGVRNILAVRGDPPGDPNGEWV
PHPQGLTYAEELVRLIRQLGDFCVGVAAFPHGHPRSADLEVDADHVARKIRAGADFAIAQ
LFLEPEHFLRLRDRLAKRGCEVPLLPGIMPITTPKVLAKFQELAGVPVPDRVSDQLLPLA
EDRAAFRAAGIELTTALCERLISEGVPGLHFYTLNRSTATRQVVTQLGLAGIAVG
>A0A1V0RLF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius mucosus|TrEMBL
MTTPRISFEFFPPKTLEASFRLWETIHALAPLDPRFVSVTYGAGGTTRELTREAVGTLHK
ATGLNVAAHLTCVDASRAETLEIADQFAAAGVSEIVALRGDPPKGSNGFVQHPDGFANSC
ELISALADTGKFTIRVGAYPEKHPEAADQRADIDWLKRKIDAGASEAITQFFFEAETFFR
FRDACAAAGINAPIIPGILPIENWVGARKFALSCGTQVPAWLDEAFDKAIRDNRHDLLAT
ALATELCSDLLDGGVEDLHFYTLNRPELTRDVCHALGVTPKVTLRDVA
>A0A423JRC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas frederiksbergensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLKQYKSAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1E7GI51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium S3730MH5|TrEMBL
MARSLEQALASGKFVVTASVDPPKGTDLEGLARLIEKLKDAVDALGISDNHNAVMCMSPW
AAGRLAIEKGIEPILHVSCRDRNRLALQSDLLAAASMGIKNILCVSGDHVAFGDHEDAKP
VHDIDSVHLLQMARALEEGRDMAGNPLKGSPTFCLGAVANPEADPLEPQLIKIDKKIKAG
ASFLVTHPVFNMRHLKIFVKHIRQSEVKVLAGIRLLVPEDIPKYKEGSCPGLFVPDSLIE
EVSKADDMGKCVKIASDSIKEIQSAKLCDGIHISAPGHEKKILDILEAAGI
>A0A6N8E6H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allochromatium palmeri|TrEMBL
MTTSTTPKRVYSVELFPPKTAEGMDKLKQEIPKINALGPAYFSVTYGAGGSTREGTFETV
AWLRSQGIDTAPHLACIGSTRAQVREILAHYHEQGINRLVALRGDLPSGMGAGNSGDFRY
ANELVSFVHAEFGGAFVIEVAAYPEYHPQSGSPARDLENFKRKVEAGADAAITQYFYNAD
AYFGFVDSCQKAGITIPIVPGIMPITNYTQLARFSDACGTEIPRWIRRRLEGYGDDVESI
RAFGHEVVLGLCRRLIDGGAPGLHFYTMNQSGPVARLWRELGLSD
>A0A7J5C5B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. AMSO31t|TrEMBL
MALGLPSVLPNPQPAIGELIRDARPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRHVIGRLASVGVRNVLAVR
GDPPGNPGGEWIKHPEGVRYAEELVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQLGTIERSVQLSGAPF
PPALAERFAAVADDPEAVRRLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWQRLR
ADAWV
>A0A6N8BUY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MSLLKDAFERGEFAVTAEMAPPKGINFSHLIECAKAIKGRAHGVNVTDFQSATLKATSLA
TCKVLKDSGLEPVLQITGRDRNRIAIQGELLSAGVFGIENVLALTGDYTMTGDHPGAKPV
YDLDSVGILQVASTISSGKDMTGHELNGTPSFYLGACVTPRYNPVELQILKMEKKIQAGA
KFFQTQAVYDIDTLRDFREKTKHLDAKLMVGIIPLKSAGMAKYMNNNVPGIYVPDELIER
MKSAENKIQEGIKISGEFIRQAKEQGLCDGVHIMAIGAEENVPLILDEAGL
>A0A7X8VGZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKISELLKRNTSSLSFEVFPPKTSTAFESVRQATKKIATLRPSFISVTYGAGGGTSDYTL
DLAKRIKELYGVPSLAHLTCVSSTRETVRERINAIIAAGIQNVMALRGDIPEHMKGSDRS
NWDYHYAVELVHELKNSGYDFCIGAACYPEIHPESSTQKEDIRYLKEKVDAGCDFLTTQM
FFDNNLLYNFLYKIREAGITVPVIPGIMPITNANQVERAIMLSGSFMPQRFKSLVDRFGS
DPDAMKQAGIAYATDQIIDLYANGLTNVHVYSMNKPDVAKKIQSNLSDILGK
>A0A6P1RIN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. LCT2|TrEMBL
MSGAMTDLTKPATADGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYGA
GGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPP
GGIGTPYSSHPDGYQSSADLVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKAKVD
AGATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARAFVTRAGTSVPDW
LAEKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRA
KSAQKAA
>A0A7X5I2L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKIRDILAKGEPTLSFEVFPPKTEDKYESVEHAALEIGKLKPAFMSVTYGAGGGTSRYTV
DIASTLQNQGVTPLAHLTCVSSTREKVTSVLEELKSRKIENVLALRGDIPADGQVERDYH
YASELIGEIRRSGDFCIGAACYPEGHVESVNKACDIHYLKEKVEAGCDFVTTQMFFDNNV
LYNYLYRIREAGVTVPVIAGIMPVTSKVQIKRICSMSGTYLPARFKAIVDRFGDNPAAMK
QAGIAYATEQIIDLIANGVNGIHVYSMNKPDVAAKIRDSLSEILK
>A0A2W5MZS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Starkeya novella|TrEMBL
MDDKVITAPTGPSAPQVGAEGPSNALRSALRDRRFFWSLEFIPSSQKVLRDDFNKLEELA
SAVSLMPTLTGFSVTDRVISDHDPDPIAAASHLMAKTGKQPLVHFSGKGRETHHLEDTLR
RMQDNGLENILMLTGDRLHEEPVGSRPRYLESVPAIAMAKAFNPNIFVAGALNPFKYREE
DGMAQYLKLGKKINAGCDLIITQVGYDIIKHEEAMYWIDGRKYNTPIVANLMPMTAARAR
YIRANQLAGVTVTDSFLALLEADEALTSDRGVARSMRRLALQILGVRYLGYAGVQLTGIH
SLTKVKELQAIVRECAEICPDRITWRRAWEEACTLPSSDRASLAPRDTPWYLLKGTTQFA
SGKARAKYHVMKFVHDWAFERGPVSRLFGTAVRAIGRRTPAGKITERVERAIKNPIFGCE
TCGMCRLAATQYVCPETCPKGLANGPCGGTAKNLCEFRDRECIHSAKYRIAKSAGRLDEL
ERLIIPAVPAALRHTSSWPPHFRGQGPAIKVAQDGRLFPLNPRNAVDDGDQSTGSNPALT
S
>A0A8B3CN03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira stimsonii|TrEMBL
MKKVSEIYGSRKGPVYSFEFFPPKTPEGDVKLMETVKELSQVNPDFVTVTYGAGGSTRDK
TVEIVTEISKNYSVPTVSHFTCVGANRDQIREILQGIRSRGIVNLMALRGDPPRGEGEFR
KTPGGFENATELISFIRSEKMDFCIGGGCYPEKHPSAKSLEEDVRHLKLKVDAGTDFLVS
QLFFMNSAFENFLNLVRKVGIQIPVIPGIMPITSFSQIERFKTLAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFTVRQCRELLEMGVPGIQLYTLNQSHASYDIVRELKG
>A0A7C6HHP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MFFFDGSFGTYYKQITKQDTLPEHANINNPDIVFKIHKGYVNAGSNAITTNTFCANSLAF
STKEEIEDCIKRGYEIAKKAAGNNTMVFADIGYVYDNSNEIFDNPQEEYLFIADTFLKLG
AKNFLFETFAEYEVAKHAMKYIRQHDKDATIHITFAVSPDGLTSKGLNYIDLIKSVVKDN
LADGTGLNCICGPAHIKQLMAQLIQTENINLKLIAMPNSGYPSRVDNMYFYDNNSSYFAK
VMAEIADLGISILGGCCGTSPVHIERMIDYLTNKKASILNTNDIGKRKEKDNEEVKRSVF
SQKLEKGEKPIAVELDPPLDTDIGFLVSSAQELKKHGADVLTFADSPLARTRACSFLTAS
RIKREADVDVMPHMTCRDKNNIGISSTLIGGAIDGIGNILCVTGDPASHGTKGVFSFNSY
NLIEYVNRMNSEYFKSTPYFIGAALNTSAPNFKNELARALKKEEMGANFFMTQPIYSKEN
IKNLKEAKKSLNSYILAGILPFASYKNALFLNNEVSGIEIPKEVLDSLEGKSNEEVREIS
ISYALDITDKVYDICDGLYIMIPLKRTDIVIEVLEKVKSRRKI
>A0A0K9GTB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peribacillus loiseleuriae|TrEMBL
MDFRQELKNRILVGEGAMGTLLYSHGIDLCYEELNITNPNQIETIHQAYLNAGADIIQSN
TYGANFHKLKRYGLEDQVSQINRKGIVIAKKVAAQGNAFVFGTIGALRSIRKSDLSLEEI
KRIFREQLYSLLLEAPDGLLLETFYDLEELETVLQIARQETDLPIISNVSLHELGNLQNG
MSLNEAFQRLEQLGTDVVGVNCRLGPHHMIRALESVSLPKQAALAVYPNASLPDYVDGRL
VYDAVPEYFASSALELREQGASIIGGCCGTTPVHIEAIKNAVRLLAPVQDKEIKVRNIEI
IEVRNSDEGVAFHEKAKVERTILVELDPPKKLGIETFMNGALALKKAGVDSVTMADNSLA
SPRVSNVALGTLLKTQHEMKPLLHITCRDRNLIGLQSHLMGLQTLGLNEILVVTGDPSKI
GDFPGATSVYDLSSLDLISLVKQFNEGLSYSGQSLGQKTNFKVAAAFNPNVKYLDKAVKR
VEKKIVCGADSFLTQPIYSVKQLEDVYEATQHLDTPIFLGIMPLTSSRNAEFIHNEVPGI
VLPEEVRRAMASAGNDPIKGKNEGVAIAKELVDAAMDKFKGIYLITPFLYYEMTAELTKH
IRKVDSRQTSEVGAYE
>E1X3E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovorax marinus (strain ATCC BAA-682 / DSM 15412 / SJ)|TrEMBL
MKIIEHLDRAKNKELLCSYEIVPPPRGRSVQDIIDIVEALQPYNPPWIDVTSHAAGAFYN
EKADGSIERKVFKKRPGTIGICGIIQNRFNIDTCVHLLSLGFTKEETEDALIELNFLGIH
NVLALRGDAPNYNKKIDTGRHTNNYAIDLVRQIDGIKKGEYISDISGARPLDFCTGVAGY
PEKHFEAPNMKFDIQMLKAKVDAGAEYITTQMFFDNEKYFSFVKECRDAGITVPIIPGIK
IIKSVRQLASIPKHFYVDFPNEFVDEVMSNQDHVKDIGLEWAIKQCEGLADFGVPCLHFY
IMNDTESVIKVVKKFR
>A0A2D6WMK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceicoccaceae bacterium|TrEMBL
VGGYPEKHPEASTQSEDIQNLKKKIDAGADFITTQLFYRNEHYFSYVDACRKVGIDCPIV
PGLMIPTALEKVERFCQFCRAELPETLRKALSQALGDAEATRAVALDWTFEQIQSLIENG
APGVHLYIMNQSEYALALHQRLASAGILKR
>A0A399I1W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
MISQLQQKLAAGRFVITSEVCPPKGADCGEFLTTARSLNRQVDAINVTDNQGANMRIAPL
AVASLLVREGIEPVYQITCRDRNRMALQSDLLGAAALGVSNILALTGDHISFGDHRQGKP
VFDLDSVQLLQAISTLESGFDLAGNKLMGTPVFFAGAAAAPAAEPFELTLFKLQKKATAG
ARFFQTQAIFDPDRLARFTTAVSPLNVKVIAGIILLKSAGMARYMNRNVPGLKVPDHIVA
EMEEASDPVAKGVEIASRIASAVRSHCDGLHIMAMGREELIPEIIKEIR
>A0A015KG48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus irregularis (strain DAOM 197198w)|TrEMBL
MKVINKILKAHEEGRPSWSFEYFPPKTQQGVQNLYDRMERMYRLGPEFIDVTWNAGGTTS
QLTSEIVATAQSVYGLETIMHLTCTNMPKEKVDKALKDAKECGCQNILALRGDPPRGQEH
WEACENGFSHAIDLVRYIRQQYGDYFGIAVAGYCEGHVDNPDKDDDLYRLKEKVDAGADF
IITQVFYDVDIFLNWVKKCRAIGISCPIIPGILPIQNYSGFNRIITLSKTIVPQFVLEEL
EPIKDDDAAVKEYGIRLAVDMIRKMFADGIKCYHFYTMNLERSTRLILEALEFVPPIENV
KPLPWCPSLSAKRKKENVRPIFWRNRTKSYIARTEAWDEFPNGRWGDSRSPAFGELDGYG
VSLKHSKKGALELWGYPQKHSDIFDVFVQYCRGEVNSLPWSDQPLAEESNIIREQLAHIN
SLGYLTINSQPAVNGVRSDHKIFGWGPKNGYVYQKAYLEVFISPTQLDALIARIERDTNI
TYYAVNKQGDLKTNTQSDGPNAVTWGVFPGKEIIQPTIVEAVSFTAWKDEAFELWNEWTK
IYDTDSISAKLITDIADNWYLINIVHNDFHDSDGIFKIFEQISVTDYEADR
>A0A0C1QQR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter soli|TrEMBL
MTATSSALSAGLAAGRFIVTTEVCPPKGSDCTEFLRKARALRPVVDAVNVTDNQGANMRI
SPLAPAALLVREGIEPILQLTCRDRNRMALQSELLAASALGITNVLALTGDFITFGDHRE
AKPVFDLDSVQLLRIIAGLNTGRDLSGSTLTGATSFFAGAAAAPEAEPFALTLPKLAKKA
AAGARFIQTQAVFSPERFARFADAAHPLGMKVIAGILLLKSPGMARYVTERVPGLKVPPE
LVAELESAGDPLAAGIEIARRTVAAVRPFCDGVHIMAMGREDLVPAIVDGMERGNSEQTT
I
>A0A2T3VDF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. RP3T|TrEMBL
MALGLPSVLPHSQPAIGELIRDGQPTFSFEFFPPKTDAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSTAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWIAHPEGVRYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVDSDTAHFVR
KCRAGAEFAVTQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIARSVQLSGAPF
PPALAERFERVADDPEAVHRLGVEQAGEMCGKLLDEGVPGIHFITLNRSTATREVWQRLR
ADARV
>A0A4P9XDE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulochytrium protostelioides|TrEMBL
MKITEKIAKAEADDRDFWSFEYFPPKTEQGVLNLYDRMERMYALGPEFVDVTWGAGGGTS
DLTIQICQTAHTVYGLEACMHLTCTNMPREKIDIALREAKEAGIENILALRGDPPRGQSE
WTSCDTGFSYATDLVRYIREQYGDHFCIGVAAYPEGHIDTVNKADDLKYLKQKMDAGADY
IVTQLFYDTELYIHWYRQVREMGITAPILPGIMPIQSYGGFSRMTFLCKTVVPQAIHDAL
EPIKNDDKAVKEYGVQLAIEMVKRLREVGIRGFHFYTLNLEKSVRLILEGLEFVAPIEVA
KPLPWNPSLSRKREKEGVRPVFWKHRLRSYILRTEAWDEFPNGRWGDSRSPAFGEIGSGG
YGGVSFKHTRDECLAMWGTPLSKDDIAQVFQEYCRGTIGALPWSEMPLAPEASSIRGQLA
RINKLGYLTINSQPAVDGVSSQDAVFGWGPANGYVYQKAYLEFFVSAQGVDALVAQIKQS
HPTVTYYAVNRAGDLRTNTQSEGPNAVTWGVFPGQEIVQPTVVEATSFMAWKDEAFALWS
EWHALYPANSPSAQHLHEIQDTWFLMNIVENNFKAPESVFELFDKAPVMNGKTQCGTLA
>A0A226PD42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colinus virginianus|TrEMBL
MVNENQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVHGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETSLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPVVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPPQQ
>N8WTJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter guillouiae NIPH 991|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKLVHQELQLLNPEFFSITYGAGGSTRERTLAAIADFN
GKGTPVAPHLSCIGDDKVRIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDADIQHFAEKVKAGANAAITQFFFNPDAYFYFV
ERIQKQGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVIKLCERLIAGGAPSLHFYSMNHTEPNRQLVLDLGLA
>A0A2L0VL89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. MG|TrEMBL
MTSNLNSLAEARRAAASPLFANLDGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLGPRFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASREEIDAVARAYWEAGVRHIVA
LRGDVPGGAPYRAHAQGYANAAELVAGLKAVAPFDISVAAYPEVHPDADCAQTDLDNLKR
KLDAGATRAITQFFFSPEAFLRFRDAAAAAGIDAPIVPGILPVSNVSQTRRMADMCGAAI
PAWMVSLFEGLDDLPSARQLVAATIAAELCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPPAAPAAEKAA
>A0A1M6F9K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio xylanivorans DSM 14809|TrEMBL
MFKDMFERDSSLSFEVFPPKKDDEFENCYNVLDSLAEINPDFISVTYGAGGSRSKKTVDI
ASYIQNQLKIDAMAHMTCVGSSEEDILAVTRDLEAVGVNHVLALRGDKPRDMSDEQFEQR
IFPHATDLIHFINQNTNLIVSASCYPEKHPEAISMDSDIAFMKMKQDMGAEMFISQLFFD
NADFYRFIERTRRAEITVPIVAGIMPITSAKQIGSTVTLAGSSVPKKLADICARYGDSPD
DMRKAGIAYAIDQINDLKRCGMGHIHIYCMNKPKMTKEICDAI
>A0A423IX93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas brassicacearum|TrEMBL
MSEDRRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A8C2XYZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capra hircus|TrEMBL
MVNEPRGNGGPGPRWEGSSSGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKH
IRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKVRGPGAGLPCPPPEPWA
GGVARSWVGGWRPHSGAGSTLTLTHGVLPLAWGGGWYWQWAMLSPWNMSCWAAAEALGML
SMEPQRRGSSLNLAVVSVYLCLSVCGTVCTCVPASLCVCFCMCDCAYLCFPVCLPASPCV
CLCVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAFLYVCLRLRVSVSVCDCASLC
LSVRVCL
>B6HK87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKVLGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRQTHGDYFCVGVAAYPEGHPADNFQDVQDPARDIPS
LVEKTQAGADFIMTQLTYDIDAYQKFEEMLRNHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIAKRMEELKHDDDAVKRAGVDIVSEIVGGVRDIPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPSYSDAGDTAIADDPASIPLDFPGRALRRRRASSINSQPHNRVIVDKL
SVHESSQDSVHEALADSAGVPAPPPNRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTANTARRLWGHPVDSKDMSAIFRRHVSGELHMVPWSEGGAEEDGEG
LNAETELIRPELLKLIDGRGWWTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFC
SSNDYTNILKPLFAKHGHDKLTWFATNVKGDFESSLPAQPADMDLDDLGSNPESVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTETYLDTTKNDSWLVCVV
GQQFGAGTKQGSKEEEDEVKWMWRVLAGEEA
>A0A6G7XDA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter viscericola|TrEMBL
MNATLLTGSAPTRARFSFEVFPARSGAAALALGHAVQHLSAADPDFISVTYGANGSNRDA
SLDLLKYLRNNTTALPLAHLTTVGESREALRQTIHGIMDAGVHDFLALRGDPPRGASESD
PSVLGSPSSVELLEIIAQVRAERPPLTSVGRTVVAAYPNGHPQSRSRSEDIDWLIAKQGA
GAQFAITQLFFRADDYLSFVAEARDAGLHIPVLPGLMPVSTSAQLRKVASLAGQPAPAEL
EHEMEAEGGFAPELGVEYAVSLARELLEGGAPSIHLYTFNRHEQVLAVLRELNLLTPSPV
G
>A0A7K4KM53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crypturellus soui|TrEMBL
MVNENQHTCSASSSSKSDGGSSSGSEGSKDSSRCSTPVLDAERHERLREKMRRRQDSGDK
WFSLEFFPPRTASGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIASTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPAGEEWQEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAENYEADLRHLKEKVLAGADFIITQLFFRSETFLK
FLKDCQAIGITCPIVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWTEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYISGELNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYETRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A8D9SCT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei (strain 1106b)|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A1I1TU03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus catalpae|TrEMBL
MKPDLRTKLKQRILTGDGAMGTYLYQMGFPVGVSYEELNMTRPDVIESVHRRYYEAGARV
IETNTFSANLVKLSKYGLESEMEAINRAGVRIAKAAAGADAYVVGAVGSIRAGRLKDMRV
SEVSEAFERQLDALLAEEVDGILFETFYDFDEMRLALGLARKVSQVPVICQFAVEGVGRT
QDGTGLLDAFSLLKDEGADVVGFNCRSGPNGIMRAVDAIGGPVELPLSIFPNAGIPDYVD
GKYTYTAGPDYFAETALRFADRGARIIGGCCGTTPEHIAAMAKALKDYAPQSDIAVAAVA
DAPEAEVIDIAAEPTEVVKDASEERAGTPIISEPSLLDTVKVRHTVIVELDPPRDLDITR
FMEGAAALKACGADAITMADNSLAVTRMSNLALAALVKEKIGLRPLVHIACRDRNLIGTQ
SHMMGLDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNQGIAFSGKPLK
QKAKFVVGAAFNPNVKHLDKAVQRLERKIASGADYIMTQPVYEPVLIEKIAEATKHLSVP
VFIGIMPLASGRNAEYLHNEVPGIQLSDEVRKRMTGLEGAAGRAEGVKISQELLDIALVH
FKGIYFMTPFMFYDMAVQLTNYVWTKTGVQRS
>A0A4Z0GZ15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacillus salinus|TrEMBL
MKLREALQEKVLIGDGAMGTLLYSYGIDRCFEELNLSHSDEVLSVHKAYVEAGADVIQTN
TYGANYNKLSRYGLEDQVKTINTAAVKLAKQATTGDQYVVGTIGGLRGIQKQTVSLEEVK
RCFREQLYCFLFEEVDGLLLETYYDLEELVAVVEIARKETDLPIIAHVSTHEPGVLQDGT
ALADALHQVEQAGADVVGVNCRLGPYHMIQSLEEVPLPEKAVLSAYPNASLPGFQEGRLV
YSTAPEYFQKSAQELYEQGARLIGGCCGTTPEHIKAIADQVKGLSPITEKQVLRHPEPTI
VSERNEDEPPRLHEVVKKQRSVIVELDPPKKLNTDRFFEGAKALHEAGVDSITLADNSLA
SPRISNAAMGALLKQNHGIDPLIHIACRDRNLVGLQSHLMGLHTLGIQEVLAVTGDPTKI
GDFPGATSVYDLSSFDLIHYIKQMNKGLSLSGKPLGASTNFSVAAAFNPNVRNLNRAVGR
MEKKITYGADYFISQPVFNEAQMLEVYEATKHIEAPIYIGVMPLTGLKNAEFLHNEVPGM
SLNPSILARMAEVNGDREQSQTEGIAIAKSLIDAAMDLFNGIYLITPFLRYEMTLELTNY
INEKTELERKMTNGIHVT
>A0A371PJJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus paeoniae|TrEMBL
MGEQLRRPNLREALAERILVGDGAMGTYLYQMGFPVGVSYEEFNVLKPEVIESVHRNYYE
AGARLIETNTYSANLEKLSKHGLEDEMEAINRAGVRIARSAIGADAYVVGAIGSIRDGKR
KNLRTKRVINAYEGQMKVLIEEGVDGLLFETFYDLEEMKLAVRIARELTDIPVICQFAVE
DAGRTADGIELADAFNQLQELGADVVGFNCRSGPNGIMRSMDSINAPVALPFSIYPNAGI
PDYVDGKYTYSAGPEYFAECARKFADRGARIIGGCCGTTPEHVAAMAASLADYVPQPGAA
AAAKRQSTVVHEPASKAAEQASFGDIHQEPTLVDLVKERHTVIVELDPPRDLDIRKFMEG
AVALREARADAVTMADNSLAVTRMSNIALAALLQEKVDIRPLVHIAARDRNLIGTQSHMM
GLDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGVAFSGKPLKQKAK
FVVGAAFNPNVKHLDKAVQRLERKIASGADYIMTQPVYDTGLIERIAESTKHLSVPVFIG
IMPLANGRNAEYLHNEVPGIQLSDEVRARMAGLEGPEGRAEGVQIAKELLDCALQHFNGI
YLITPFMFYDMAVQLTQYVWEKTKQ
>A0A828YSB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. malvacearum str. GSPB2388|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A7C5TPZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon|TrEMBL
MSFRQKLEKGSFVVTGEVTPRKSGSAKGILKDVKALKDVVDAVNVTDNQRACVRASSVAV
SKTVLDLGVEPILQATCRDRNRIGLQSDLLGAYLLGLRNVLALTGDHPSNGDNPGAKPVF
DLDAVQLVKAIDGLNHGVDFEGNTFDDKTDFFIGAAANPGAEDLEVEILRVKNKIEAGAR
FFQTQVVYDVDAFKAFMKEVPSEAKILAGIVPLKSVKMANFMNEKVPGVNVPKALIDEIG
SSKNQVDAGISQAAEIIREVKSSCSGVHIMALGLEERVKDIMALAGLKGKV
>L2F6M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella macacae 0408225|TrEMBL
MTQYLTLINRLNDIENLVGALKTDLHEQATKQKTSKTFKKVPFSFEFFPVKTDEGQEKLM
TTFDELNALNPKYFSVTYGAGGTTRERTLGIVKALIERSNTPIAPHMSCIGDNKKQIGEL
LDFYKSLGITRLVALRGDLPSGQVGYGELPYALDLVKFIRHHSAEHFQIKVAAYPEMHPQ
AKSFAHDIEQLIAKYHAGASEAITQFFYNADSYLYLRDELAKKGIHQENFPITAGIMPIT
KASSLIRFADSCGADVPRFMRKKFADFGDDSRAVQAFGFDVVISLCERLIAEGVPALHFY
SMNHVKPNKSLVTELGLI
>R6XFD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. CAG:592|TrEMBL
MTTENKPYFSFEVLPPLRGKGIDSIYRTIDRLMPFDPAYINITTHRYDTLYSELANGTYK
KLSVLNRPGTVAIAAAIKERYKVRTVPHIICSGFTAAEIESELIDLSYLGITDLLLLRGD
KAKSDNRFIPTPEGHAHAIDLCQQINRFNNGQLLGGVQNEMLTEPFTYGVAGYPEKHDEA
MNMETDIENLKAKVNAGAQYIVTQMFFDNSKYFAFVKRLRKEGINVPVIPGLKPLTTLNH
LTMLPKTFHIDFPKRLSNELMKCKSNDDVKAVGVEWAKHQCRELRENGVPGIHFYTMNAS
QSVEKIMNGL
>A0A3S2B685|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.08.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A4S2RL53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. A1277|TrEMBL
MTTLRETLAGPDPSVSFEFFPPKTEAGMRGLWQAIRRIERVAPDFVSVTYGAGGSSRDRT
IEVTKRIVAETTLRPVAHLTAVGHSVAQLRHIVGQYADAGVRDVLVLRGDPPGDPNAPWV
PHPQGFLHAHELVSLVRELGDFSIGVAAFPERHPRSPDWESDIRHFVAKCRAGADYALTQ
MFFHVEDYLRLRDRVAAAGCDIPIIPEIMPATDARQISRFAELSGAAFPEDLAHRLNAAR
DDPAQGYRIGVEYATAMAERLLAEGAPGLHYITLNRSTAAPEIHRAVTGSRSVRRVEMAH
R
>D0IE87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. RC586|TrEMBL
MGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWNSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWNNGIQNIVALRGDI
PAGGGKPDMYASDLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPNWMVKQFEG
LDEDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A1I4D971|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium canum|TrEMBL
MWSPGPRPLKLIYMTDRSFELVCEVEPPTRPDLRHVRHQIGTLSKIAHSFLIPDNHIGRA
TVSSVAVAHEVQKMGGRSIACINSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTSGNR
TSDLTVRSMIEEVRSLGEDPAFAQTPAFRVGTAAGLRPLPAWKRTADFMFVQVSFSVEAL
LRWREANPVDLPVYAGVMVIASENHARRLADAIPDIDIPAGLVERVASDRLAGVEAACEQ
VLRIRDSGAFDGVHLIPVARYREVESRLSGIL
>A0A1I6ZSF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora righensis|TrEMBL
MTTNAQQQLQRYLRNARYEVLPLRGVVEQVRELPAGTTVTVTSSPAKGTEATLDTAARLR
DEGMHVVPHLAARLVRDSAHLSDLLARVSDLGLTEVFVIAGDAERPAGRFTDALSLLRGM
EEIGTRPYRLGITGYPEQHAFIPDRMTIQATDEKARYADYIVSQICYDPNTIASWVKSMR
ARGVELPVYIGAPGSIDPSKLLRISMKIGLGQSMRFLRKQHGVVTKLLTRYTPENVFDEL
SPCLVDPDYNIAGWHLFTFNEISKTRQWAIEMADRLQEVPA
>A0A3S2VD43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium umbonatum|TrEMBL
MIASYDALSEARKALDTPLFAGLPGDVAVSFEFFPPKSDAMMLQLWDVVQALAPLAPEFV
SVTYGAGGTTRDRTHGTVARIISEARLPAAAHLTCVDATKAEVNAVAEAYWEAGVRHIVA
LRGDMGEPGAPFVPHPEGYQNAADLVAGLKAIAPFDISVAAYPEMHPDSASPEADIDNLK
RKLDAGASRAISQFFFEPETFFRFRDRLAAAGIDAPVLPGILPVSNFAQTRKFAAACGAA
IPAWMEGLFAGLDTHPAARQLVAATVAAEFCRRLYAGGVRNFHFYTLNRAELSYAICHLL
GVRPKAAAAIQEKAA
>A0A2H3NRF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Longimonas halophila|TrEMBL
MKVTEHLDRASNPLISYEIIPPKRGGSAEQMLGVVEELMPYEPPFIDVTSHSAEVSYKPM
PDGTWKRCVKRKRPGTLGLCAAIEARYGIDTVPHILCKGFTREETEDALIELNYLGIDNV
LAIRGDDKGVEKDLSPDRSRNEYAVDLVSQITDMNQGAYLEDLMDAQPTNFCIGVGGYPE
KHFQAPNMAWDIMRLKQKIEAGADYVVTQMFFDNAYYFEFVEQCRSVGIDVPIIPGIKII
TRKRHLQSLPAHFHTDIPEALAAEIAAADSDEEVKHLGIEWALQQSEELLSANVPCLHFY
IMSSATTVKEVVEPLREMA
>A0A1Z9N0L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium TMED211|TrEMBL
MTNIKSDLKVSFEFFPPKNEQMEETLWKSLKRLEPLNPQFVSVTYGAMGNTRSRTHELVK
KIIRKTSIQPAAHLTCVGSSIDEINEIAENYWKDGVRHIVALRGDSPVDIKQNIFELEFA
TDLIKVLKKVNDFEITVSAYPECHPESKNTEQDIDYLKKKIDLGATRAITQFFFDNEVYL
NFLNKVRKKNIKIPIIPGILPITNCKRTLEFSKSMNCTIPYWLQNMFTGLDSDPETRKLV
AANIAADQCKELVKEGINEFHFYTLNRADLSFAICHILGIRTLKD
>A0A845L5W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heliomicrobium gestii|TrEMBL
MTRVTIELVPRSEDALISELEMVQQEFPQIMGINIPDLLRFPLRSWDACTCAKRYFSTAI
PHIRAIDLNPDAPLQMAEQLQRDGISEVLIVTGDPPHDMSRKVYPTTSIDVIRRFKRELP
AMKVYAAIDPYRYSLRQEYDYIKRKIDAGADGFFTQPFFDLRFIEIYGEMLEGQQVFWGI
SPVTTEKSACYWETKNHVVFPAGFQPTFEWNINFAREVLAYMAQTKTNVYFMPIRTNIRT
YLQGIFGV
>A0A0G3ABK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces incarnatus|TrEMBL
MNPALTVTPAVGAALLDDFSLEMTGKDVPRLEEAQGSIPRGTRINITFLAGEDLGMRLAA
ARAVKRLGFVPVPHISARRLPSRAALEEFLSGLAEDGTADNVFVVGGDPARPEGPYPDAL
AVLRTGLLQRHGVRHVGISGYPEGHPAIADGTLWTALTDKTAALGAHRFAGDVITQFGFD
VDPVLGWLEAARARGVHLPVRIGVPGPAGVRRLLGYATRFGVATSASVARKYGFSLTNLM
GTTGPDRFLHALAHRYDPERHGAVKVHFYTFGGLRRTADWIAGFRQAVRQVP
>A0A672HBU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salarias fasciatus|TrEMBL
MVNQKQRVEGAWQSSKSDSSNSTSGGESSKESSRCSTPVLDADRSDRLRDKMRRRIESGD
CWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQTREVITGHLAKAKHLGLKNIMALRGDPMGTDWEEEEEGFNYAVD
LVKHIRAEFDSYFDICVAGYPTGHPEAESYEEDLLHLKEKVEAGADFVISQLFFRADTFL
KFLDDCRRIGISCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITEVIEPIKDNDAAIRNY
GIHQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELMNEESVFEVFTSYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELDKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVSALLKVLKKYEPRVN
YHIVNVHGLNLTNAPELQPNAVTWGIFPGREIVQPTVVDPVSFVSWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELINENPTYITEAQTSS
PGPKPGNLEEDANTKIVNYKDINCNFSRFFNKLSPFLLFCLQLAS
>A0A6B3NKA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symploca sp. SIO1C4|TrEMBL
MSNAIQNSKSQIATETVSLSNYLQDTTPTKNSFRHAAESGKFLITAEVTPPKGGNPAQMV
KMAKTLKGRVHAVNITDGSRAVLRMSSLAASVILLQQGLEPICQLACRDRNRIALQADLM
GANALGIRNILALTGDPVKAGDHPEAKSVFDLESVRLLQLISKLNQGVDAHDKPLTDDVT
DLFAGAAVDPQLKSWSGLQRRFERKIEAGAQFFQSQLITDFERLEKFMDEIAAGSNKPIL
AGIFLLKSAKNARFINKYVPGVNIPEAIIERLAAAKEPLLEGMNIAAEQVQIAQQICQGV
HMMAVKREDLIPQILDLAGVEALHN
>A0A7S9M1Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. HF-162|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPKELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A1F3STN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionales bacterium RBG_16_40_8|TrEMBL
MATSLYERGFFINRSFEELSHVEPRAVQEVIRNFKKSGANILHTNTFNATRTKLTEHGLQ
DNLAIIVEKSASLALEVAGDDAFVLGLLGPLGVLVEPLGPTSLQEAEDMYAEIVCPLEKA
GVHGYAINALHDFNELECAIRTVKRMSEKPLFVNIGLHENLKTSYGHTLPQFAELAKKYK
IDVIGVCGEVGPSTMLTAIEQLRPLTDRPIMALPNAGLPRYVNDQYIYLCNPDYIGKFAK
RYIQAGALIVGGHSGVYDSHIRAIANSIKMVQHQTEIAFKQDLPSLIQPIVDKPTNVKPL
TERSKLGAALYNGEKVATVELVPPSLADFAKFESRCRELEEGGIKFVNIPDGARAMARVN
SLQLAAHVQRNFKLEAIPHLTCRDRNLIGLQSDILGAHIAGVRNILLITGDPPKLGNNPG
ATAVYDVDSIGLTHIVSRMNHGLDIGGSATNYPTAFVIGAAMNPTARNIELESRRFKYKV
EAGCDYAITQPIYNLETYKRYIEEIGDIKIPVIMGIWPLVSLRNAEFLKYEVPGVDVPDW
VVEEMKKAGDSKDEALKRGVDIAIRTMEQAKNIVSGFQVSAPFNRADVAIKVIKSIF
>A0A1S7U556|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium salinitolerans str. Hayward 0363|TrEMBL
MEWPDETDLVKPHVNELGGELRRRCKPVLPQQAQTSPQNRCMVIKRITHKLPDISAAPII
PASIEASPAQVLGASDLAGLFPQGVRVYLTDTGAASQDRLVEAAAHLRNLGYEPVPHLAA
RRIPSSAAFVEQVRRLAGEAGVTDVLVVGGGVERPVGPFASSMDMLSTGIFDRCGINQIA
IAGHPEGSPDFNDDTAMAALRLKRDFAERSDAAMRIVTQFGFDPARFIAWAEGLIASGIE
LPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTTLARGHSPESIVGPIERHWQ
ASPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGAADRAASPDSRAG
>M5CN21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia SKK35|TrEMBL
MSARAPARAAAFISRYSLEVSAKALPALRAEADRIAPGTIISIPYLASEDDNARLAAARI
VRQLGFEPMPHLSARRIESRAALERFMQRAASEAGVERCLLIAGDLAAPAGPFADSVAII
DTGILEGSGIKVVAIGGHPEGHPMMGSGERWEVLERKCQAIEARRMAPLIITQFAFDADI
VLAWLDDLRSRGIRVPVLVGVPGPASITRLARYAAMCGVGASASMLARYGISIGRLLGPA
GPEVFVDRLVQGLTDAHGAVSPHFFPFGGIAASLAWIERYQRHALASSPS
>A0A2N2JVG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-15|TrEMBL
MSEAKTPSKLEKTLRAGHLAVTSECGPPRGSDAKAITAKAEMIRDYVDAINITDNQTSVT
RLCSLASCIHLKLMGVEPILQMVTRDRNRIALQSDILGAASFDIHNILCLSGDHQSFGDN
PKGQNVFDLDSMQLIQTVRHMRDEGKFLGGDPIQRPPRMFVGAAANPFADPFEIRVPRLA
KKIAAGVEFIQTQCIYNLEKFELWMKLARDRGLHERVFILAGVTPLKSAGMAKYMKNRVP
GMDVPDEIVKRMSGVAKEKQAEEGLKICVESIQRLKEIEGVRGFHIMAIEWEEKVPEIVQ
KSGLYPRPKID
>A0A3S0DI70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseriaceae bacterium|TrEMBL
MRVIEHLNQAQKPLFSYEIVPPLRGSTTNINEIFNIIEQLLPYDPKWINVTTHASSLLYV
EKSDGSITRRIHKKRPGTLGICGVIQNKFGIDAVAHVLCQGFSQQETEDALIELNYLGVE
NILALKGDNLNYNRQLDVAESVNKHAVDLVKQVAKMRQGLFLGDTEYPAIDFCTGVATYP
EKHFEAANMELNIEYLKQKIAAGAEYVITQMFFDNQKYFSYVAACRAAGITVPIIPGIKV
LKSANQINSLPRLFHVDLPHELVAQILQAPQDAARIGKEWAAAQVAELLEAGVPCVHFFL
MNDVTSVLDIVRKYN
>A0A3N8GSI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Bp8998|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDNLRAILDQYRSHGIRHIVALRGDLPSGMGSVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAATATRTICERLSM
>A0A0A0DQ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquabacterium sp. NJ1|TrEMBL
MTTPQRLPISLEFFPPKTPEGVDKLAAVRQQLYPLKPEYCSVTYGAGGSTQDGTIQTVRA
ILREGFDAAPHFSCIGASKDSVRAQLAQFKADGIKRLVALRGDLPSGYGGFGEFRYASEL
VAFIREETGSHFHIEVGAYPEMHPQARNPQADLQAYVAKVKAGADVALTQYFFNADAYFR
FVDDATAAGATIPVIPGIMPITNSTQLMRFSDACGAEIPRWIRTRLEGFGDDKASIQAFG
LDVVTALCEQLRAAGVPGLHFYTMNQSATVLAICQRLGV
>A0A290WQS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium svalbardensis|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRIKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRASIRAVLADFKAAGVSRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLQAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A4U1HIS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polyangium aurulentum|TrEMBL
MSSDSSTPPPRPQRFLEALRRGVLVVDGGMGTQIYERGVLFNVNYEELVVSRPELVLRIH
DDYARAGAQVIETNTFGANCIRLARHGYADRVRELNVAAARLARKALGDRGHVAGAIGPT
GLVLAAFGEDDRCRMRDAFREQAEALAEGGVDALMIETMRQPEELFIAIEGVRQAVGDSL
PLVAEVSVDEQLTLADGSTIAEIGARLRDRGCDVIGVNCSDGPQLVLSAIEKLLPLGVPL
AAVPNAGLPRRVDDRFIYVSTPEYFGVFARRLCKLGVKLIGGCCGTTPEHIRRIAAAARM
EASAVASANEDAGPLWVGASESGYPAEADADEPPSVQGGCPVPQAEKSKLAAKVGQKFVI
SVEVNPPVGLDASAALKAAKMLTDGGVDVINIADGARAQARMSNVAMAVMMERELGIETL
VHVCGRDRNLLGQVAHLLGAHALGVRNLVVVTGDPPKMGDFPDATAVYDLDSIGILRLVS
KLNAGIDPGGKKLGCGTSFFCATGAEPAALNYEREIERLKRKKRAGAEMIMTQPVYDLAV
LERFLRDAEPLGLPILIGILPLASHKNAEFLHNEVPGMQIPKDVRDRMQKAGSGPLARKE
GVAIAREMLSAVRRRVAGAYIMPPLGRYELALEVMDGIV
>A0A7Y6DH43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas corrugata|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRTLLARYKAAGIQRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVNKANAGANSAITQYFFNADSYFY
FVERVRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EDVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLNLPR
>T0HIH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. HDIP04|TrEMBL
MTLGFPSVEAAQAWQAPLYADLAGDVNVSFEFFPPKSEKMEEQLWSAIQTLTPLGPKFVS
VTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASRAEIDEVADAYWEAGVRHIVAL
RGDPPEMGAKFEPHPDGYKGAAELVEGLRKRHPFEISVAAYPETHPDAQSAQSDIDNLKR
KLDAGATRAITQFFFEPDTFFRFRDTVAAAGIDADIIPGIMPVSNFAAVQRMSAMCNTDV
PGWMGKLFEGLDDHAAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVAANAV
>A0A7C9IJQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp. AETb1-6|TrEMBL
MTKATDNASRGPSRSDIRLSFEFFPPKTADAEKQLWETATQLSAYDPAFLSVTYGAGGST
KVPTLATVRHLLGMGLPAASHLTCVGATKEEVNAVVAEFQAIGVKHFVALRGDPPGGVGT
AYQPHPGGYANAAQLVAGLRGLADFEVSVSAYPEKHPQSADVAADIDMLKRKVDAGATRA
LTQFFFDNDQFEHYLERVRRAGITIPVVPGLLPVHNLAQVQKFAGMCGATVPAWLAERLS
PVDDKPQERTAVAVELAVRQLEDLISRGIDEFHFYTMNRANLVSAVCDGVGLAKVDRRPA
AGAAA
>Q5SNW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Homo sapiens|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLH
>A0A0D0IZ48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella pectinovora|TrEMBL
MTTENKPYFSFEVLPPLRGKGIDSIYRTIDRLMPFDPAYINITTHRYDTLYSELANGTYK
KLSVLNRPGTVAIAAAIKERYKVRTVPHIICSGFTAAEIESELIDLSYLGITDLLLLRGD
KAKSDNRFIPTPEGHAHAIDLCQQINRFNNGQLLGGVQNEMLTEPFTYGVAGYPEKHDEA
MNMETDIENLKAKVNAGAQYIVTQMFFDNSKYFAFVKRLRKEGINVPVIPGLKPLTTLNH
LTMLPKTFHIDFPKRLSNELMKCKSNDDVKAVGVEWAKHQCRELRENGVPGIHFYTMNAS
QSVEKIMNGL
>A0A4R8ZMU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT1-19|TrEMBL
MPHTSDPACRKIPFSFELYPPTSDAATSVLHATIERLAAAGPEFISVTYGANGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSNAEASQLIREFLDAGVRSFLALRGDPPEGIREGEAF
LGDLGSAAELVQLIHRVQAERVPYREAVIPGLPAARTIKREREKVRIAVAAFPNGHPRSR
SATQDIDALLAKQAAGANLAITQLFFHADHYLSFILRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRQATELARELIAGGAPGLHLYAFNQHE
TVLAVLDGCGLLTPTLPASAQPAPHPVKENR
>A0A084XVB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter sp. SK-01|TrEMBL
MTPQPPVFSLELFPPQTPEGAEKLRAARARLALLKPRFFSVTFGAGGSTRDRTLETVLEI
QREGHQAAPHLSCIGSTPASIRSILEQYQAHGIRHLVALRGDLPSGMARPGTFRYANELV
EFIRAETGDWFHIEVAAYPEYHPQAKSPMDDLLAFKRKLDAGADSAITQYFYNFDAYAHF
IDECQAAGIDVPIVPGIMPISSYSSLARFSDNCGAEIPRWVRKKLESYGDDTLSIHAFGL
DVVSSLCAKLLASGAPGLHFYTLNQVELTTTLWQRLGLSKAISM
>A0A1I6R5W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium wenxiniae|TrEMBL
MKIVDHIKNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYLYKQ
HASGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTPGGHAYATDLLQQVADMNQGKYLHEDIAISEKTDFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFYNVEKYKEFVTKCREHDIHVPIIPGLK
PLTTKKQLIALPKIFHLDIPEELSDAVSACKNNAEVQQISTEWMVNMCQELIEFGAPVLH
FYTMSNPGPTKKIVEQLA
>L2EN01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp. HMR-1|TrEMBL
MTDRYFSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSTRDSIRTILQTYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQARSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRAMGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDKEAIRAFGLDV
VTDLCARLLDAGVPGLHFYTLNAAGATKAVWQRLKL
>A0A0J9GS37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rhodobacter lobularis|TrEMBL
MALLNFRKKTAPATSTPDVEAFLRGYSIEVMPRTATKVEDFREILAPGTRVYIAHIEGTP
IEDMVETAKRIADEGFDVMPHFPARIIQDAATLADWIARYQGEAGVRQALLLAGGVAQPH
GDFDSSMQLLETGLFDKAGFTHLHVAGHPEGNKDIDPDGSDKNVMEALRWKQSFAERTDA
KMALATQFAFEAGPIIEWVDALQEAGITLPVHIGIAGPAKLQTLIKFAIACGVGPSLKVL
QKRAMDVTKLLLPYEPTEVIAELAAHKAANPGFGIEQVHFFPLGGIKTNATWAIENGGAS
TAPLAATA
>A0A4Q5IVC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides iriomotensis|TrEMBL
MRNRRHAELLARLVADARYEVLPTPSVEDTVLTHLPRERVITVTASPGKGLGATLDLAER
LAGHGYLVVPHLAARMVHGRGELAEICERLTGKGIARVFVPGGDAEADGTYPDALSLLED
LADLGRPFSHVGIAGYPESHPTIHDDLTVQSMWDKRRYATHVVSNLTFDPGTIRVWVRRM
RDRGITMPLLLGLPGPVERTKLLAMATKIGVGESTRFLVKHKGTLARLAAPGGFTGERFL
EQCAPALAMPDANVAGLHVFTFNQIEATETWRNDLLHQLTR
>A0A3R6V0X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium OM08-6BH|TrEMBL
MKISQALREKTLLSFELFPPKTEKGMENLPGTIDHLMKYKPAYISCTYGAGGGNVGANRE
VCQMIKKAGTTPVTHFTVIKNTKEGIKEQLDQYLAEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDTYGDKFEIAVAGSPEGHIACRSLDADIAVLKQKQDNGADYIMTQLCWDM
EQFRYWLDAIREAGITMPVDVGVMPILDMGATINMALSRNGCVMDSELCRMISRHWLFPN
PFAAKDADGKPFDMFYDKKVEEFKEEGIQYTIRQIDEYRAMGVNGIHLYALNKWKDVSRI
IDESGLCTLV
>A0A1Y0UW53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter ascendens|TrEMBL
MSLSRLSVELIPRSAEALAADVATVKAHFPAADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQPGLEEILVVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMQGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLDANIQFAQTVLKELAQEKGKAYLMPVRIKLEQY
LPALLDAVA
>A0A2A2GB94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliifodinibius sp. WN023|TrEMBL
MKVIEHYERATEPLISFEIIPPKRGGSVNKVFESLDKVMKYNPPFIDVTYHAAESYYEEL
PDGTIKRHIKRKRPGTIGLCAAIKHKYDVDPVPHLICEGFTKEETEDALIELNFLGIDNV
LAIRGDAPDDSTPRIKNGTYNKYAIDLVKQVKGMNQGEYLEDIVNAHETNFCVGVAGYPE
KHFEAPNLDFDVARLKEKVDAGGDYIVTQMFFNNDAYFRFVEKCRAAGIECPIVPGLKVL
TRERHLNFLPKFFHLNIPEALSNEVQANPGNAREIGVEWAAQQCTELLEGGAPGIHFYIM
GDPTPALDAVDKIPLGKTAKAGT
>A0A2T7WFN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium testaceum|TrEMBL
MSELPLIDTCPKSMEYGPCGGVGFDGSCEVDAGHLCAFLPRPTVPWTGLDRTTGVAPAAR
TAAAAQTLDALGTRPWVVADLPVRALSVASIDRGAAILAGEVDAVLAGDAGNARVQFPPA
YRAHLLQRRGLRVWTGLNMRDRNRVAIEGELAALAVEGVAGVHCVTGDHTRTGHRPDAAP
VFDLDSTEATALARAAGHVVSVAASPAAPPVDRRAARLREKIRAGADVCFVNHAGGAAPV
RRFVDEAGDGIRYIPCVPVVVDHASADLLESFTTLALPEGFVERVRRARDPRAEGIALAV
EMAQQMLAVPGVVGVNLSGGREGAEEPFAEALAEIARRLR
>A0A2V7RYG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYGKGFFLNVCYDELNLKQPKLVQEVHEAYVRAGAEILETNTFGANPVKLGSFGLA
EETEKINQAAAELARRAAAGRASVAGAIGPLGVRIEPFGPTSRDEAFAHFRRQVQGLLAG
GVDGFILETFSDLDEIHEALRAARSLCDLPVIAQMTIGTDGLTHYGTDPQTFAKRLTEWG
ADAVGVNCSVGPAGLLEAVEQMVKVTDRPISAVPNAGLPKDVGDRKIYLASPEYMASYAR
RMIETGARIVGGCCGTTPEHIKKIRDYVASVVPRHQPTVTSRETVSPPAGVAAATLAKRS
GWGAKLARGELVTSVEIVPPKGVDPTPMLQQSRALKGAGVDAVNVPDGPRAQSRMGVLPS
AILIQKEVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLTNLVYRLNHGLDPGNNPIGAPTQWVIGVGVNPGAVDLDRELSRFAWKVDAGA
DFAVTQPVFDLDQLEQFLKRVEPFHTPIVAGIWPLISLRNAEFLANEVPGVSVPESVLAR
MRQAQEKGKEAALAEGVAIARDMFEQVKGTVQGVQVSAPFGRVEVALEVFGA
>A0A7Y2B516|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MKIPFRERLLQGPVLFDGGMGTTLYERGVYINRSFDQVNLGDPELVRSVHEEFKAAGAEV
LTTNTFSANRAKLKRHGLADQVVDINRRGAEIAGQAAGDEAWVAGCVGPLGVQIEPLGPL
ALSEAREMFAEQVEALVAGGIDLFICETFIYHSELAEAVRACRQVAPDLPILAELTITDD
AGSLTGASPSQVLTDLLSVGADLVGVNCSVGPHVMLEWLETVRENTEVPLSVMPNAGKPR
DVEGRNIYLSTPEYLASFTKRFLQAGASVVGGCCGVSPAHLKAMARTFRAESAMSVAKRA
PIEAIEAPPEVEPRALYDKSRLGGKLATGRFVTLVELVAPRGTSAKKELEAARRMHVLGV
DCINIPDGPRAMARMSALSLAIQIQREVGIEAVLHYACRDRNVIGIQSDLLGAWALGVRN
ILAITGDPPKLGNYPDATAVFDIDSIGLTNILNRLNHGLDIAANPIGEPAAFCIGVGADP
GALNLEEELKRLYWKLEAGAEYIITQPVFDLDVLNRFLEKVARFDVPVIAGLWPLQSLRN
AEFMNNEVPGCSVPADVIERLRKCESREAAREEGLAVALETFRRMKSEIQGIQIAAPFGR
TEAAQRILDEIL
>A0A8F7XGG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. LJBS17|TrEMBL
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLVPITEKEVKTRAKEFIS
VHHERTEPGLDEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALIKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMAHAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>A0A7W1C9U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MIEVRRQGPTVAERIRAGRFVSFELWPPRSPESAAALEVALEELTALNPAFVAITYGAGG
ATRERTHDLVVRLAESSLLALAHLTCAAHTRAQLVELMQRYRRAGVGSLLALHGDPPLSA
TDELPQGDLRYALGLVRLAREVGLQCVGVALHPEGHPAAASREEDRRHQAAKLREADFGL
TQFFHRRDDYFALVEQMSSRGADAPIVPGVMPITNVRQVERMAAMSGTSVPIKLAARLHA
VADQPDEVRRIGVEQATLLCKELLEGGAPGIHFYTMNRAAATLEVCSNLGIGGAAHALGK
DRPRNDRP
>A0A6L8DPT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MNTSLLDHLRSSMLVADGASGTMLYARGVPMEVCFDEINLSRPDLIRKIHEEYVDAGAGL
IETNTFGANALSLSKYNLEDQAETLNARGVEIAREAAGSRAFVAGAVGPARGLPHWDYTK
ADHRRVHAEQIAALAGGGADAIILETFLRLDELKAALAVCQEICDLPTICQLAVDQYGQS
DDGFEVVEAFDQLRAAGADVVGVNCRSGPKGLLDALAPVPLSEGLVLSAFPNAGSPVYVD
GRFIYEATPEYFATSALRLRDQGVRLIGGCCGTLPEHVQAMARALEGREIVTRKKVLPVE
VRVPARPERIARPVPAPPAVEPSIVDLVKERVTVIVELDPPRDLDHGPIVRGALALKKAG
ADALTMADNSLAVTRISNMAVGQIVKEEAGIRPLLHITCRDRNLASLQSQVLGLHALGID
HVLAVTGDPVKFGDQPGASNVYDVSSFELIRLIKQMNDGVGFSGRTLNGRTAFTVAAAFD
PNGPNLDRRIRRLERKVEAGADMIMTQPLFDRRQAKQLYEATRDAGVPIFPGVMPLVSDG
NTEFLHNEVPGFVVPDDVRARMARVGRGRKARREGVAIARELIESVLANFNGLYLITPFN
RYPMTVELTEFALQATTRNSPE
>A0A2V7LW34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTTTLRDLLDDGKVHVLDGAMGTMLYSKGFFLNVCYDELNLKQPKLVQEVHEAYVRAGAE
ILETNTFGANPLKLGSYGLADDAEKINQAAAELARRAAAGRASVAGAIGPLGVRIEPFGP
TAREEAFAYFQRQARGLVAGGVDGFILETFSDVDEIHEALRAVRSVSDLPVIAQMTIGDD
GLTHYGTGPETFAKQLTAWGADAVGVNCSVGPAGVLEAVEKLVKATDRPISAVPNAGLPK
DVGDRKIYLASPEYMASYARRMIEAGARIVGGCCGTTPEHIKKIRDYVASVVPRHQPTVV
SRETIAAPAGVAEVPLATRSCWGAKLARGELVTSVEIVPPKGVDPTPMLEQCRALKAAGV
DAVNVPDGPRAQSRMGVLPSAILIQKEVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRN
ILIITGDPPKMGPYPEATAVFDIDSIGLTNLVYRLNHGLDPGNNPIGAPTQWAIGVGVNP
GAVDLDRELSRFAWKVDAGAEFAVTQPVFDPAQLEAFLARVEQFKIPIVAGIWPLLSLRN
AEFLANEVPGVSVPESVLTRMRRAQDKGKEAALAEGVKIAREMFQQVKRTVQGVQVSAPF
GKVEVALEVFG
>C6E085|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp. (strain M21)|TrEMBL
MGGSFLERVAHEVLIGDGAIGTMLYAKGVALDANFEHLNLVRPQLVLDLHAEYLAAGAQV
IETNTFGANYAKLSAIGIGGKVADINRQGAILARRAAKGCDVFVAGSMGPMGRGKKEMSD
DQVRDSFRLQAAALAEGGVDLLILETFSELDELETALAAARETGLPVVANLAFGEGSRLA
GGIEAEDAALRLAAAGASLVGANCGAGPLELLATLKRMAAVTDLPLAAYPNSGFPEYVDG
RYIYRTTPDYFAARAEEMVAAGAVLVGGCCGTTPEHIRVTARRLKGARPAARVAAGEVHR
PPVAEKAQSAASGFLDRWGKEMVVTVELDPPKGLDCSRILAGSRALKEAGADAINLAENP
LARVRMGNLALASLIRREVGIEVIAHITCRDRNLIGLQSDLMGASLLGVSSILAVTGDPA
SLGEEAGASSVFDLNSFTLIKLLSDLNRGVNALGNPIGAGTGFTIGAAFNPNTQKMEVQV
ARLAKKVENGACFAQTQPIYDLERFEQMMEQTAHLGIPILPGVLPLVSGRNAEFLHNEVP
GITIPDGIRARMAGKVGEEGVREGLAIAREFIEATLGRVGGFYLIPPFGKYEIAVELVKF
IKSKAEHRGL
>A0A8D5XZ98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. (strain Tol 5)|TrEMBL
MAGFPACMTLSDRVRSDEDIAPLIAAQAYPDHIEKVLHYAGKGRDIDDFKLFLKQADSVG
LRDILLLTGDKLKQHHDGQGQHARTRYLESVNAVMAAHQYGGFHIGVAFNPFKYTPAEQQ
AQYLKLHKKLNAGADYIITQLGFDLSALKQLQTFLAQEKYIQKTLACVMPLTLARAQFMV
KHKVAGIVITPHMLEILTQDQVNHCPENVYKRCALQILICQHLGYAGVHLSACHKADEQM
LLEQYIEQYRDLNLSQCEILWNQLWQLAEGEQLRPKVAAKRIKSALNNKVKYQFLDLIHR
AMFQSSFMKGVGTFIFNASFWNRKTAAKVLLQTEYLSKHYLLGCESCGQCRLAETLYICP
ETCPKGLANGPCGGTDLDRCEFGDRECIHSVKSRLAHDVDQIQLLKEQLIPTVPIEVRGT
SSWKNWYKAE
>A0A831T224|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MGEEAVRDFKEALHEDRVYLFDGAMGTMLYSKGVYINRSFEELNLVEPRLVQEIHRAYVK
SGAQILITNTFAANRVKLAARGLEEQIKEINYKGAKIAREAAGEDLYVAGDIGPLGIRIE
PWGPTSVDEAKEAFKEQAEALLDGGVDLFVLETFSDLNEIHQAIRAVRELCDLPIVAQMT
VADDGNSSYGTSPEIFTKRLDEWGADVIGINCSVGPRVTLETIEKMVPVTRKKLSAQPNA
GYPRNIDGRNIYLASPEYMAKYAKRFIQVGVKFVGGCCGTTPEHIKAIANEVKALSPSRK
ISVTMVPEDQRPQVQPIPRREKSSFARKICEGRFVASVEIVPPKGCDPSGVLQGVRLLKE
AGIDAVNIPDGPRAMSRMGAIPLAAIIEREVGIEAIFHYCCRDRNLLGMQSDLLGAYALG
LRNILIITGDPPKMGPYPDATAVFDVDSIGLTNMVRQMNQGMDIGGNPIGKPTGWHIGVG
VNPGAIDLDREIKRFEWKVDAGAEFAVTQPVFDVEVLKKFLKRIEHCRIPVIAGIWPLTS
LRNAEFMNNEVPGVSVPPPVMERMRKAEGKEKAREEGLAIAREALMEVMELVQGVQISAP
FGKVQYALDVVEGIER
>A0A2V7IJC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYSKGFFLNVCYDELNLKQPKLVQEVHEAYVRAGAEILETNTFGANPVKLGSYGLA
DDTEKINQAAAELARRATGGRASVAGAIGPLGVRLEPFGPTSREEAFAHFQRQARGLVAG
GVDGFILETFSDVDEIHEALRAVHSVSDLPVIAQMTIGDDGLTHYGTGPETFAKQLTAWG
ADAVGVNCSVGPAGVLEAVERLVKATDRPISAVPNAGLPKDVGDRKIYLASPEYMASYAR
RMIETGARIVGGCCGTTPEHIKKIRDYVASVVPRHQPVVVSRETIAVPAGVEEVPLAARS
CWGAKLARGELVTSVEIVPPKGVDPTPMLQQCRALKAAGVDAVNVPDGPRAQSRMGVLPS
AILIQKEVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLTNLVYRLNHGLDPGNNAIGAPTQWAIGVGVNPGAVDLDRELSRFAWKVDAGA
EFAVTQPVFDPEQLEAFLARVGQFKIPIVAGIWPLLSLRNAEFLANEVPGVSVPESVLAR
MRRAQDQGKEAALAEGVKIAREMFQQVKKTVQGVQVSAPFGRVEVALEVFG
>A0A7C2IBT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MSKKDFREALTDDRVLVFDGAMGTMLYSRGVYINKCYDELNLTTPDLVLGVHREYVKAGS
DIIETNTYGANRVKLAGYGLEDKIREINRTGARLAREAASDRAFVAGAIGPLGIRIEPYG
PTSIEEAQAFFREQAEGLLEGGVDLFILETFSDVAEIHQALIAVHSICDLSVIAQMTIQN
DGNTSYGTSPEIFTRRLDEWGADVIGLNCSVGPHAMFEAIEKMQQVTRRKLSAQPNNGLP
RQVDGRMFYMASPDYMAKYAKRLIQAGAKFIGGCCGTTPEHIRQIANAVTALSPGRSTVS
AFVIEEKPDVVVTPAEQKSRFANKICNGEFVTSVEIVPPKGCDPSKMLESVRLLKEDGVD
AVNVPDGPRAQSRMGVLAVSTLIEQQVGIETVVHYCCRDRNLLGMTSDLLGAAALGLRNL
LIITGDPPKMGPYPEATAVFDIDSIGLVNMVNRLNNGLDIGGNPIGGPTSFFIGVGVNPC
AVDLEYELRRFEYKVEAGAEFAITQPTFDVEQLRSFLKRIEGFRIPVIAGIWPLVSYRNA
EFLANEVPGVVVPERVLDRMHRIADKDAAREEGLAIARETLVEVRDLVQGVQVSAPFGRV
QYALDVFRV
>A0A849HI18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
LERELRAGGFVVTGEIAPPLGAAPDVISQKAEMLRGYVVAANFTDNASASARMSSLASSK
ICLEAGLEPVMQLQARDRSRVVLESDAIGAAGLGIPNILCLSGDHQRFGPGPVAKPDQFD
MDAIQLLWMLRRMRDEGMYLDGRKINQPPKFFLGAAASPYGALPEYEAIRAEKKINAGAQ
FIQTQPVFDYDRFLDWMEALDRRGLLGKVHILAGLIPLKSARAAEFMANEVPGVVIPDVT
VKRMTEADGKEAQQEAGFQIAAGILRKLMETPGLSGTHIMAVHWESIIPRLLEETGLRQD
VPAAHT
>A0A8D1C5Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MQRSSAMVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMES
GDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIAST
AVNYCGLETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYA
ADLVKHIRSEFGDYFDVSVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADT
FFRFLKACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIR
NYGIEQAVSLCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHP
KRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKE
ELLKMWGQELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVN
RRGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELR
VNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQW
GKLYEEESPSRMLIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEA
SDPAP
>A0A7X4DZS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MPDLRSLLSDGRVHVLDGAMGTMLYDRGVFVNVCYDELNATHPALVEEVHAEYVRAGAEI
IETNTFGANPVKLSSFRLEKRTEELNRLAAEIAARAANGRAAVAGAIGPLGIRIEPLGPT
SREEARDYFGRQVDGLLEGGVDGFILETFADLAELEQAFRAVRDRCGLPVVVHVTVGEDG
KTATGASARQAARAAEAWGADALGLNCSVGPAVVLDGLERMAEVTTLPLSAQPNAGLPRA
VGDRKMYLTRPDYTARYARPLIDAGARLLGGCCGTTPEHIRLISERVAAIQPRRTSVRVA
HAPAAAAAASPAPPLAERSELGRRLASGEFVVSVRVMPPRGWDTAALVRDCRTLAAAGAN
LIAVHEDRGAGRLDVLATAAIIARSCPGTEPLVHYTCRDRKLPRMMSDLLGAAATGLHNV
LLLTGDPPGPGPYPDYRSVVDLDSIGLANVVAGLNTGVDPSGNRIGGPAAFAAGVALNHT
ARDREGELRRLHWKVDAGADFAVTRPVFDPGQLRGFLAEVEHGIPVIAGVVPLETARQAE
FLQHEVPGVHVPEPVVERMRRAQARGTKRAATEGVEIAREITEALNGEVAGIQVAAERGP
AEALLAALDL
>A0A554R1F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. KBS0724|TrEMBL
MTFDAVRGRSSDGWASRTPSIVDRITSSTGSRIPFSVEFSPPRDAEAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSIDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPDGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
HDTKYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAFDPEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGSQENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTSDVSTDTQASV
>A0A512M7P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevifollis gellanilyticus|TrEMBL
MHIADILNQQRPTLSFEFFPPKTNEAFEALYQTIGELEAYKPSFVSVTYGAGGSTRELTH
DLVVRIKKTTTLDPVPHLTCVCHGESDIASILERYAEAGVSNILALGGDPPRNLEGYDRK
KDAFQQAADLVRFIKKFNESGAHPDKRGFGIGVAGFPEGHPNTPNRVLEMDYLKAKCDEG
ADYICTQLFFDNHDFLDFRDRCRLAGITIPIIAGIMPITSASGMKRMADLAAGARYPAKL
LRAIQRAGNDEAAVQRVGVHYATEQCRDLLENGVDGIHFYTLNKSHATREIYASLGIRDS
SAVRSA
>A0A509YJ71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas jandaei|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPEMYATDLVALLKAEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLENDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQP
>A0A1B0ZNA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter gallaeciensis|TrEMBL
MKTPDISFEFFPPQSLEASFRLWDTVQVLAPLDPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVQATKAETMEIADRFAEAGVSEIVALRGDPPKGEGKFTPHPDGFANSV
ELIEALADTGKFTVRVGAYPDQHPDAATAQADVDWLKRKLDAGADEALTQFFFEPETFFR
FRDACEKAGIDGSKLTPGILPIENWKGARNFARRCGTKIPAWVEDAFEKALRDDRADLLA
TAMCSELCTELLEGGVEKLHFYTLNRPELTRDVCFALGITPKVSLENVA
>A0A416SQN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF19-22AC|TrEMBL
MKIKELFKQKTVLSFEVFPPKRTGSIHTIYRTLDELKELRPDFISVTYGAGGSENCRTTL
DIASAIRNDYGIESAAHLPCMGLTKEDILTQLGQFKEAGIENILALRGDYVSGLESRGDF
QHADELISFIRENGDFHISAACYPEGHNESADIVADIRNLKRKVDAGASHLISQLFFHND
YFYKFRERCTLAGIDVPIEAGIMPVANKKQIERMVSLCGVHLPSKFVTMMERYEDNPEAM
RDAGIAYAINQIVDLISQGVDGIHLYTMNNPYIASRIYEAVHRLIAA
>A0A516X4A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tomitella fengzijianii|TrEMBL
MALQVTGMPSVVESIAAHDSGTTPFSVEFFPPRDEAAEARLWRTVRDFEQLRPAFVSITY
GAGGSTRDRTVRITGEIAEHTTLTPVAHLTAVDHSIDELRAMVGSYADKGIRNILALRGD
PPGNPLGEWCAHPEGVHYAEELVHLVRELGDFHLGVASFPEGHHRSPDLDHDTRYLVRKL
RAGAEYSITQVFFDVDDYLRLRDRIAAADPEQGAKPIIPEILPITSLRSVRRMVELSGSA
LPPLLEERLAAAAGSGPQEDRAAVREIGIEFATGMAERLIAEGVPALHFITLNFSRATRE
VLQNLGLVAAPAAG
>A0A2U1WCY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. TSA6c|TrEMBL
MTAPTSALPSISFEFFPPKSEKMEQSLWQSIRRLAPLSPSFVSVTYGAGGSTRERTHATV
CRIQDETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGQYEP
FPGGYAYAADLVAGMKRIANFEISVAAYPESHPEAPNAQFDLDNLKRKVDAGATRAITQF
FFDNDAYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPAKLAETFEGLDD
DPETRQLVAATVAAEQCQALQAQGVNDFHFYTLNRSDLTIAICRMLGVKAKAAPAAAAVA
G
>A0A368VNP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopolyspora algeriensis|TrEMBL
MTTNTQQQLQRYLSQARFEVLPLSGVLDQADTLPRDATVTVTSSPSKGTEATLDTAAQLR
SKGFHAVPHLSARLVTDRSHLAELYSRIDELGLSEVFVIAGDSPTPAGEFTDALSLLRAT
DELGLRPPRVGVTGYPEPHAFISDQTTIQALDEKSRYADYIVSQICYDPNTIVSWVKAVR
ERGVTLPIHIGAPGSVDPKKLLRISLKIGLGPSMRFLRKQQGVVTRLLTRYTPETIFDEL
SPYLLDPDYGIAGWHLFTFNEITKTRKWVDEMAARLQEVPA
>A0A3A9SLH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. X503|TrEMBL
MKIIDIIREKEVTLSFEVFPPKTDDGYAAVEEAAAEIAALKPDFMSVTYGAGGGTSKNTA
NISADLQNKYGVNVLSHLTCVSSTKEDVRAMISTYKEKGIENIMALRGDIPKDGRVCYDY
DHATQLIYDIKSVDDSFCIGGACYPEGHVECARQSEDILHLKEKVDAGCDFLTTQMFFDN
STLYQFLYRIREKGIEVPVLPGIMPITNAKQVARSVALSGSTIPQKMKIMVDRFADNPEK
MKEAGIIYACDQIIDLISNGVSHIHVYSMNKPDIAAGMMRNLASIIR
>A0A1N7PKB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Belliella pelovolcani|TrEMBL
MKITEYISQAEKTLFSFEILPPLKGQSLKDLCEGIEPLMEFQPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFQVEAVPHLLCGGFTKEETENALIDLNFIGVQNV
LALRGDAPKSENKFVPEPDGHAFTKDLVAQIIGMNQGKYLHEETETGFQTDFCVGVAGYP
EKHFEAPSLKFDLKHLKEKVDAGAEYIVTQMFFDNAKYFDFVKKVRDLGITVPIIPGLKP
ITTLGQITMLPRTFFLDLPDALMDELEKCKTNADVKQVGIEWAIQQSKELITAGTPCLHY
YTMSKADATYKIAKEVF
>A0A7V5KHV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MRLNEIYARHQPAISIEFFPPKNEEGDKVLAKRIEELRRFNPAFCSITYGAGGSTRERTL
AWARKLKHDFGLETMCHLTCVGHSRDELRRILEQLRDDGIENIMALRGDPPRGESTWKPH
PDGLAHAVELVRLARSIWDFGIGVAGFPEVHPEATSAEDDLRHLKEKVDAGAHVVITQLF
FDNEDYWRYVAAARAVGVNVPIVPGIMPFRSVAQLEKFTTVYARTKSGPARVPPRLRAEL
EKVAEDPEAVARLGIDYATRQCQDLLANGAPGIHFYCLNESDAVSSILSNL
>A0A7R7ZQ77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus chevalieri|TrEMBL
MEKLTEKIAALPPNSNYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AKRSLELAEVCQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNIHGEDDSNKDFMFAVDLVRYIRQQYGDYFCVGVAGYPEGHPADSFQDVQDPHQDLPYL
IEKTKAGADFIMTQLTYDLDAFKNYESLLRNHESGVFKTIPIIPGLMPVHSYKIMTRVTK
LSHVKVPPHITKKMEEVKHDDDAVKRVGMDVITDIVKGIKKVPSPGIRGFHFYTLNLEKT
VSFILERCNLIPDYDENAIEDEGEFNVTSSTLDVAPNGSRLGSKSRASSLNSQPRNRVIV
DRKQEKLEDATRDSASHEASAVSAGMPAMPPNPSTTLQISEGLGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVPAPAARRLWGHPVSRSDLNTLFRRHVSGELHMVPWSEGGA
EEESGGLNAETAVIRPELLKLIDGRGWWTLASQPAVNGVRSNDPVFGWGPHNEGFVFQKP
FVEFFCPDKDFQNSLKPVLEKHGHEKLAWFATNANGDFESSLPAHPAGSDNDDLVEMNPD
NVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPRGTATERFLEDTKND
VWLVCVVGQEFGAGTEVGSSEEEKEVKWMWRVLAGEE
>A0A5J4KZ72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hot springs metagenome|TrEMBL
MSFKDALNSGKFVVTAEVGPPKGTDIKEMIHHIELLKGKVDALNVTDNQSAVMRICSMAV
CKIALEHGVEPILQMTCRDRNRIGLQSDLLGASILGIKNVLCMTGDHVLAGDHKQAKPVY
DVESVQLLRIVDSLNNGKDMAGNELKGATDFFQGAVVTPEANPIEPQLIKFEKKVRAGAK
FFQTQAIYDINKFKEFMSYARKFPVKILAGIVVLKSAGMANFINNNVPGIRVPQELIDEL
KAAGKEKALDTGLNIAARHIRQLKQENICDGVHIMAIGMEDKVPIIMERAGLI
>A0A7Y6UQS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. HO-A22|TrEMBL
MSMTAFARHDLETALFRNYSLEITGKDIGQIEAARSAIPAGTPINIAFLGNETHAQRIEA
AARIRQWGFEPVPIISSRRLRSVEDRDELLAGLIGAARPTRFMFVGGDPSSPAGPYKDSL
DLIAGGIIADHGIVHVVIAGYPEGHPRIERARLWEALEQKIGLLKAHGCTMEITTQFGFD
ADAIVDWIAQVRARGIDVPIRIGVPGPADVKRLLRFAAQFGVASSAGIVGKYGFSLANLV
NKVGPDRFMTRLEDGMRGRDLGTVLLHLYPFGGIGETVAWATGAAGRKMTERAHVIGDCR
>A0A7C4L830|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKIIDILKNNKFSFSIEVFPPKPDTDIQIIYDTIEKLMDIKPDFISVTYGAGGSTRIRTV
EIADKIQNYYKITTLAHLTCIGSTKEEIAKILDDLKNKGIENIMALRGDIPKNQDTPFKD
FKYASDLVRFIKNNWDFCIGVAGYPEKHPEAKSMEEDLRYLKEKIDAGADFITTQLFLDN
NHFFRYLESVRSKGIKVPVIPGIMTATKLINIERMANLCKVEIPNSFKNALSGSNINNEV
CEETVKYTVGQINHLIKNNIKAIHLYTMNKVEQNKRIYYESKLSEIRK
>A0A7D8A869|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium esteraromaticum|TrEMBL
MSTTPFSFELYPPRTAESARALHDTIDRLAEVGPEFISVTYGAGGSTGGRSLEVLRYIRA
HTDTEPLAHLTCVGNTYAGAARLIREFLDAGVLSFLALRGDPPAGQDEDDVFLGDLESSA
QLVQLIDRVQAERAPYEESPVRGNPGAVRVAPRRKVNIAVAAFPNGHPRSAYSSQHVDAL
LAKQAAGATVAITQLFFHADHYLAFVERARRAGVTIPILPGIMPITSPARLTRVLELTGE
DLPGELAIDLEIEPTTEGRRQIGIRWASDLIRAVVDGGAPGVHLYAFNQHETVLDVLQSA
GIIPERQLSAASKGTS
>A0A7C1VLC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
AELGPPQSANGELIRKKSEHFKGYVDAVNITDNQTAIVRMSSIAAAAILMGEQLEPVIQM
TCRDRNRIAIQSDILGAAALNIKNILCLSGDHQKFGNHQGSKNVYDIDSIQLLSVVRGMR
DEARFASGDAIKTPPKMFIGAAANPFADPFEFRVIRLAKKIKAGAQFIQTQAVFDLPKFK
DYMKLVYDRGLHEEAAILAGIIPVKSVRALQYMRSEVAGMSVPDELIKRMEAAQDPKEEG
IAITLELIEQIKEIPGVKGIHLMPVMWESSIPVVCEKAGFLPRPPQN
>A0A415CCN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM12-1|TrEMBL
MRVDEVFKQAASQGTAPISFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRSHADIAAKIDEYRSAGMENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDVGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A4P7ZA91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. TSA2s|TrEMBL
MTAPISALPSISFEFFPPKSEKMEQSLWQSIRRLAPLSPSFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGRYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDAYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPKKLAETFEGLDD
DPETRQLVAATVAAEQCQALQAQGVNDFHFYTLNRSDLTIAICRMLGVKAKAVPAAAAVA
G
>A0A330L2Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira lenta|TrEMBL
MSKEPRRLSEVLSSGQFAVTIEYNPPKGTNISKVLESAKSLVGRVHGVNVTDNTAAVVRA
GSMPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGHDMAGNKLDGSTAFTIGAAVTPEADPVGPMLAKFDVKV
KAGAQFFQTQAIYNPDLFATFMTAVRPYKVKVLAGILLLRNHKMAEFMNANIPGVSVPQE
MIDELKAAGDKAEDVGVEIAVRTINAVRAHCDGVHIMAIKGTHRLADIITKAQLG
>G9P292|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypocrea atroviridis (strain ATCC 20476 / IMI 206040)|TrEMBL
MHIKNLVADTEKTKAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLEKVNDALQKAYKAGCTNILALRGDPPRDQTT
WTAADGNFRYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEDSLLDHLKEKVDMGAGF
IVTQMFYDADNFLRWVGRVRERGITVPILPGIMPIATYASFLRRAKHMQCRVPPEWMTLL
EPVKNDDVAVREIGKTLVAELCRKLLAGGIHHLHFYTMNLAQAVRMVLDELDWTPSAERP
LKQALPWKQSKGFGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTCVQDIADTFVQYLEKKIETLPWSESALAAEADPIKDDLVA
LNKRGILTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLVPPYLLDEMISRLDDFP
NLTYYAVTKNGELRSNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFDANTPSRALIEGIMNEWYLVNIVNNDFRENNTIFSFLQGLQVKDASVPANGTA
>A0A286TXL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Scalindua japonica|TrEMBL
MSEEHDTNNNNLKSGSNLEKLLKKGEFVVTSELGPPRGASREAVEEKAKFLKGYADAFNL
TDCQTAMVRLSSIASGAILLNMGMEPVVQLTCRDRNRIAMQSDILGAAALGMKNLLCLTG
DHQCFGDHPEAKGVFDLDSINQLDMFRQMRDEKKFQSGEELKTEEPKLFLGAAENPFSDP
FQYRAARLAKKVKAGADFIQTQIIYNVEKFEKWMSMVRNMGLHKKVFILAGVTPIRSLGM
AKYMKKNVPGMDVPDEIITRLEGAEKKKAEGINICLEVIERVRKIEGVSGVHIMAVEWEE
IVPEITERAGLLPRPTP
>G4TRD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serendipita indica (strain DSM 11827)|TrEMBL
MRLSEKIDNLDSFTPFYTFEFFPPRTEQGFENLVSRIGRLSTLNPLAVSITWGAGGSTKD
WSLKLADICRNDHSVDTIMHLTCTNMQPGMVEDALRTAMEKGIRNILALRGDPPRGADSW
IPSDPRFTSATDLVKFIKTTPEFRDYFCIGVAGYPDGHAETTASEEEQIQYLKKKVDAGA
DFIITQLFYDPESFLTWQENVRKAGIKIPVIPGIMPIQTYASFMRLIKLCGTKVPDSLMA
QITPIRNDDQLVKDLGVEVAVSMIRKLQQSGVQGFHFCTFNLEKSVQRVLEQLGWVGRHV
EQHNMVISESPSRNNQPGSLPPELVITASDIAASTSYSLKQAHPGNGPNNSAGKGELNAA
GTWDEFPNGRFGDFKSPAFGVKDLWDHGITALPRNAVELWGRPTHTADITTVFLRYLRGE
VPSTPWSDSPLSPESKSLVPLLTKLNERGWWTVGSQPAVDAVPSEDEVHGWGPRGGYVFQ
KAFVEFFCTRDDVAALEARAKEKGKGWVTFFAANMMDDYATNMTDEGSNAVTWGVFPGKE
INSPTIIERDSFLAWKDEAFGYWTEWGLFYPPDSAERKLLDSVRDERWLISLVHHNFKDP
DGLWNFLLD
>A0A1J5DR13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG2_30_43_15|TrEMBL
MVSSFKKALESGKFVVTSEVAPPKGTNLEKMVHHIELLKDKVDAINITDHQSSVMRFPSL
GGALLIKEMGGEPILQMTCRDRNRLALQADLLFASSRGIHNVLCLTGDSVLLGDHKEAKS
VFDLDSSQLLAAIRRLERGKDLAGNDLDGGISFCAGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVYDLDRFKQFMDYARQFPAKILAGIILLTSAPMARFMNKNVAGVNVPQEPID
EMASAPKGRAIEKGIEIAGRMIMRIQEERMCDGVHIMAIGREELVPDIMAAARLV
>A0A151FLP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium liaoningense|TrEMBL
MTDVTTPATADGHLKRPAISFEFFPPKTEEMERNLWDTIKRLAPLEPKFVSVTYGAGGST
RERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPVGGIG
TPYSSHPEGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDAGAT
RAITQVFFDNDLYFRYRDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWFAAK
FDGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAKSVQ
KAA
>M3BZI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces gancidicus BKS 13-15|TrEMBL
MRDMLAGGKTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSVTYGAGGSTRAGTVKA
TEQIAADTTLTPVAHLTAVEHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWVPHP
QGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFF
QPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNAVFPDALKERILTAKDDP
AAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>V6A8E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa MH27|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A520WDA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MDFISVLTEGNGLVAAELRPPRATLDPRAGMEAWIDTYHAVEGLARLGTYSFLTDGAVGE
QEEHNLRHLIANLGDDVPRKHIVPFLTTKHTLNYCLRYADRAWETGFRSLVVLGGDTTVG
LPRVVPHGADLRQLIRTRQPQLTLGGWANPHGDIDDQVDFLLKNNVTADFFLTQVVSHHD
RIAVETFVAAAHRRQLTLPGVFGVFFYRSASIDTFKFLARFLPIPAAHLTAEFEAGLTAI
QICARSIAMLRQLGVNNIYVSNLPVGSAAPTLKAILFEAEQMTGRIL
>A0A1J5D4I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG2_30_43_15|TrEMBL
MNNSSKLKRVLEGGGFAVTAECGPPKGANPDVVLKKAEMLRNKVDAVNVTDNQTAIVRMS
SIAACSLLKTAGLDPVLQMVVRDRNRIALQSDILGASALGIRNVLCLSGDHHIFGNQPQA
MGVFDLDSIQFVQVVRTMRDEGKILGGDGLSQPPDFFIGAAANPFADPFDFRVIRLAKKI
RAGADFIQTQCIYNLDRFERWIGMARDRGITDKAYILGGVTPLKSPGMAKYMKNKVSGMD
IPDEIIKRMEGVPKDKQREEGINICVETIQRLRGVPGIKGVHIMAIEWEEVVGEIVERAG
LLPRPVFD
>A0A368ES02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKITDYLKKSNKTLFSYEIIPPFRGGSIDKVFNLVEELMPFDPPFIDLTSRSAESYYQDD
GSGKLVEHIRRKRPGTIGISAAIKNKFNVETVPHVLCNGFSKEETEDALIELNYLGIDNI
LAVRGDELRKRKKNQDQISNKYASDLVKQIQDMNTGKYLEDLLDANKTNFCVGVGGYPEK
HFEATSLDADIETLKYKVDCGADYIVTQMFFDNNIYFQFVDLCRKNGIEIPIIPGVKILS
LERHLKALPKHFYLNIPPELVSSVEGKSKSEIKIAGIDWATNQVQELVDYGAPCIHFYIM
SSAKSATKVVSNFI
>A0A0K8PWV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces azureus|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSTDWDTDVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDRVSAAGCDTPIIPEVMPIASARSLERIPSLTNAAF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHRPQA
>A0A497LJG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MGRMIVVRPKPLDELLGYLRGRRKVLIVGCDGCTTPPRGLREAQTYANLLELAGKLKGEN
FSLKATTLPKTCDSHIVYSSLAGQLEDVEAMVSLACGIGVQVLNEVFPQIQTFPGNDTVF
NGMQPKEGGVFEERCLSCGSCLLGETGGICPVTMCAKGLLNGPCGGFFEGKCEVGNWVND
CGWVKIFDRLKELGKLDIFTKIRLPKDYRDMQNPRKLSIAEVATKKAIPEVIDEVKEPGK
RPAYSELMKKIRNGEFVVTGEVEPVKTTDLTEVLEAAESLKDYVTAINVTDNPTAFAYMN
ALIPSYIIQEKTGVEAVYQMVARDRNRLALVSDLLAAGALGIKNILALSGDTTTMGDNPE
AKKVWDLDVTQFIYMISKIVDEGVDLAGNKIQNPPKFNVGSSANPCATPLEPEIYKLVRK
QNAGAEFLQTNSLYDIEIIKHFLSECRSAGLKIPILIGITPFKSVKMMDWLVKYVPGVVV
PDEIQEKLRKAREKSKEAFVDKNIEIFSELCREIRKTTSAVGIHMMAIGFEWVVPKILEE
AGL
>A0A7J4P2V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MTYELLPPRGCETNGFEVVATIVDKLDAVTVTDNPMATLRASSIAYGSKAKEKLHLDVIP
NLSCRDRNLLALQSEIIGADMLGHNNLFIITGDAPRDREGFKPVWEVNSIELCGIVKGLN
EGTATVRGSEQAINGSTRFTVGGALVFDRPNEQDTLRKKVDAGFDYFISQISFDAGQALD
FFAEAEERGDRVDRHVQIGLAPTSTPRRLRAVSQMPGIKIRDTTLEKLEGNPDFLGGIVS
HLAEVADDLKSSLSTYSIGFHLMPIGSDEATHRLVEELT
>A0A5S4VPI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] rectale|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNQYNVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
EALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>A0A3D1NJY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKYTGTAGILYDRLKSEILVADGAFGTYYAKKYDTGSLPELANLQASDRVLAIHKEYIEA
GAKIIRTNTFASNTVCLGAGFDEVRNNIKNAVDIAREAVKGTDVLVAADIGPIPGENMIE
KEHIEKEYVDIVNVFKECGVDIFVFETFPELGFIDKAIENAGENGFVITQFAINQFGYSS
AGFSARKLIEEAEKNSYIDACGFNCGVGPGHMKKLVQSLINRNDKYFAVLPNAGYPQVVS
GRMVFDDNNAAYFSQIMHDLAEDGADIIGGCCGTTPEYIRQMVLKTADVVHKKNASIEEE
ITEKKTANDVSFYKGKEGRKLIAVELAPPLGIDDEKIMDAAFLMKESGVDVLTFPDSPSG
RTRADSILMAEKVSRETGMCVMPHICCRDKNAIAMRSQLLGAHINDINNFLVITGDPIPS
VVRASVKSVFNFDSVGLMNIISDMNQEQFAGKPVIYGGAINQGRVNFKVELERVKKKMEA
GATFFMTQPVFSDEDIDRLRQIKEQTGARILCGIMPFVSLRNATFMKNEMTGINVTDEIL
SRYRADMSKEEGEETGIQIAREIIAKTTDFVDGYYFSFPFNRVHMLKKIIGKNNQ
>A0A419KK81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MGLREGVKLSRRVYSELMSQIRSGKFVFTGELEPEKTTDLKEVIEATLRMKGYVTACNVT
DNPQSFAYISSLAAAYLIQEKTGVETIYQLTCRDRNRIALTSDLLGAGALGIKNVLALTG
DHSTLGDMPQAKPVFDLDSVQLISMIRRMVDEGVDISGNEIEKPPKFHVGAGANPNAKPL
EPEIIKFIKKVEAGAEFFQTQVVFDVETVKRFFNEIGNCNVPVLIGIFPLRSYGVAEYFD
KTVPGVKVPEELMTALAKAKKISDKKRRREKYNEINLEYFTNLLREIKKTTPAAGCHLMS
VGYEEIIPDLVKAVKP
>A0A550GNQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
LAMAYMNSLVPSYVVQRDVGLETVYQVVVRDRNRLALTSDILAAAYLGIKNVLAISGDHT
VLGDNKGGRAVYDLDSAQFVYLLKKMIDEGTDLQGNEIHGKVEINVGIAANPNANPLDPE
ILKIGRKVKIGADFIQTQTMFDIDLTKEFLKETERFSCPTLVGIFPLKSFGIADFFDKYI
PGVSVPRDLLEAMEKCKEEPDKEKRKDRYDEVNMEFFSPFIKEIRKTTSAAGIHVMAVLY
ERILDPLLRETM
>A0A2I2GG85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus steynii IBT 23096|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
ATRSLELAEICQRQLQLTTCLHLTCTNMSRALVDHALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDNSNKDFTFAVDLVRYIREQHGDYFCVGVAAYPEGHPADSFQDVQDPERDLPYL
VEKTQAGADFIMTQLTYDIDAYTKFENRLRTHESGAFKTIPIVPGLMPIHSYKILTRVTK
LSHVQVPPNVLAKLEEAKHDDDAVKRIGVDIISNIVDGMKDIPTPGHRGFHFYTLNLEKT
VSFILERCDLIPPYSEDSDALVDGGSLSALDSSSYVAPNGAPIRSLTRRRASSINSLPHN
RVIVDRVQTPGGSSKDSTSHEAPATSAGMPAMPPDRNTTLQISEGLGALGREATWDDFPN
GRWGDARSPAFGEIDGYGPSLHVPPSIAHRIWGHPASREDISTLFRRHVSGDLYIVPWSE
GGAEEGGNGLNAETDIIRPELLQLIDGKGWWTLASQPAVNGIRSSDPVFGWGPPGEGFVF
QKPFVEFFCPSADYHNVLKPILTRHGHEKLAWFAANAHGDFETSLPGPTSDADPLEMNPA
NVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPRDSPSERFLEETKND
VWLVCVVGQDFGAGTEIGSQEEEDEVKWMWRVLINSK
>A0A1G3TNG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp. RIFOXYB12_FULL_35_9|TrEMBL
MFDELINKLKNDTYITLETTPSHSPVFSPIIETIAELGLDKLVDGFTTTDNPLAKLKYNS
LFAAKMLQDRFHKPVIATMSMRDRNKIALQSDLLGANEVDVRAILALTGDPATISDQPHT
KGVFEADSTLLLDIISCFNSGIDYGGKPFTFKPKEIYPFAVINSYAKNPKTLQKKMQKKI
KHGAIGIITQPIYDIQSAKLLLELKEATEHSSSAELIFGIFPITKLRTAQFLSAHVPGIN
VPNYWIEALRVANEKGVEEEYRVGFELSKKLFEDLKALHPKIHLMTANQFQIAKDILK
>U7NUH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. C1S70|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTREEIGELLDVYKENGINRIVALRGDMPSGMGASGELRYAN
ELVEFIRQHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEQMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTDMCEKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A1E7I834|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp. S3730MH75|TrEMBL
DNSLEIVKQMKQNAGIEPLAHLTCVGASPENISGFVNSLREAGVENILALRGDAPSDVED
FDFSTQDFQQASDLVTYVKDNHAGMGIGVAGYPEAHLESPSIKEDFKWMKYKVDEGGQFI
ITQLFFDNRVYFDFCNRLAEMGINVPVVPGVLPIMSLKSAKFILSLCGAAIPGKFLSALE
KAHADGGDDAVYRLGIDYATKQAQGLLDGGAPGVHLYTLNRAKACLEIGQALKFK
>A0A0H5A9B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas trivialis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKSDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITHMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1E3LLW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea sp. ISTKB|TrEMBL
MTQPSFSFEFFPPKTADGAEKLRATREQLFPLGPKFVSVTFGAGGSTQQGTLDTVIEIQR
EGVEAAPHLSCVGSTKDNIREILNTYRGNGIRHIVALRGDLPSGMGEIGEFRYASELVEF
IRAETGDWFHIEVAAYPEYHPQAKSPRLDLEHFANKVKAGANAAITQYFFNADAYFRFVD
DASRLGVTVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTALCERLLKDGAPGLHFYTLNAASATKAMWQRLGL
>A0A5M9QYX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morganella psychrotolerans|TrEMBL
MSFLHVDQHEALNQNLAELAGRVEVSFEFFPPGTPEMENTLWQSIERLSVLKPKFVSVTY
GANSGERDRTHSVIKGIKEKTGLIAVPHLTCIDATRDELKTIAKDYWDNGIRHIVALRGD
LPDNSRKPDMYAADLVNLLKSVADFDISVAAYPEVHPEARSAQADLINLKKKIDAGADRA
ITQFFFDVSTYLRFRDRCAAAGIDVEIVPGILPVSNFKQLQRFAGMTNVRIPGWLGNMFE
GLDDDPESRKLVGASVAMEMVKILSREGVKDFHFYTLNRAELTYAICHTLGVRPAVACVA
>Q4QKH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae (strain 86-028NP)|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDSGANHVII
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A1T1H2S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 5600|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGDHFKIEVAAYPEMHPQADSFDLDIKRFCDKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGFA
>A0A4Q7NGW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Motilibacter rhizosphaerae|TrEMBL
MSATTVSECPKRMVHGPCGGVAGDGTCEIGPFPCPFVGRAVVPWSGPPTPHTSEPPLLAL
LRQRPVVIADLPAPPLSRSGLERSADALAGAVDAVLLGDAPTARVQLPPAHRAAVVQSRG
VAAWAGLTCRDRNRVALEGELAALADVGAAAVHCVTGDHTRTGDRPDAAPVFDLDSTRLA
AVAAQTGLLVSVAESAAAPPREQRAERLAEKVRAGAAVCFVNLCDGPAAVGEFVAAATDA
GAHVPFVACLAVAFDAGSAAALQRFPGSVRPAYGVAEAVRLAEAYLDVPGVRGVDLTAVP
APGRELETAGALAEIGRALR
>A0A2T0U6S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcticibacter pallidicorallinus|TrEMBL
MKITEHIENAAGKTLFSFELIPPVKGNGIKQIYDTIDPLMEFNPPFIDVTYHREDYIYKQ
HPTGLLEQVAYRKRPGTVAICASIMNRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARKADASFIPTPGGHAYATDLLEQVSNFNQGKYLHDNYDTNRTDFCIGVAGYP
EKHFEAPNLKTDFGYLKKKVEMGANFIVTQMFFDNQKYFDFVRTCRENDIHVPIIPGLKP
ITTAKQLINLPKIFHIDIPEDLSDAVSACANDKAVKECGIEWMIHQSKELMAFGAPVLHY
YTMSNAEPTRRIAEAIF
>A0A7C3PGB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
ARAARDEAQSEIWIAGSIGPLGRPLAPLGAVLPAEARQAFAEQAAALAEGGADVLILETF
TDLAELTEAVAAAREVTRLPIIAQMTFTHEGRTLWGHTPAEIVARLDDLGVAVIGANCSV
GSQGVLQVMEQMVLLTRTPLSAMPNAGFPSYVDGRIIYFSTPAYMADYARQMVDLGVTIV
GGCCGTTPAHIAAMHEALATATAPSPARRRAPAAVPARPAAPVPAPPTALGERLGRRFIL
TVEVAPPRGTQEGPELEACRLLRDAGIDAVNVPDNPMARLRMSPWAMSLRIQTEARLETI
LHFTTRDRNLMRVQSDLLALHALGIRNLLVLRGDPPQLGDYPTASAVSDVKPSGLIRAVK
QFNQGRDLAGNDLGHPTAFLVGAALNMGARDLDHELRVLEQKLRAGVDFLCTMPIFEVET
LDRVLNRVGTLPVPLLVGILPLHSLRHAEYLHNEVPGMSIPSALRAVLRGAPAETGVRLA
ADLVTSIRPRVQGAYLIPSFGRYDRLLPLVQMLRASPAPTEP
>A0A7Y0TI57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobiaceae bacterium|TrEMBL
MLVKEILNAAVNPVFSFEFFPPKKDEEWETLFATIAALSPLNPSYVSVTYGAGGSTRSRT
HNLVTRIQKETGLTVVSHLTCICSDRDETGSILENYQKNGINNVLALRGDKPAGVASIDD
AIKDFPHAIDLVGFIKTNYPAIGVGVAGFPEGHPETPNRLKEIEYLKEKIDAGADYIVTQ
LFFDNRDYFDFVERCAIAGITVPIIPGIMPISTKKGLIRMAELALGARVPAPLLSKVLNA
ENDTEVASIGIEWATNQVQELIDHHIKGIHFYTLNMADATLRIFNNLHQ
>A0A6L5YHP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Waltera intestinalis|TrEMBL
MKIRDILNKDTATISFEVFPPKKSTDFGNVEAAALGIAALQPAYMSVTYGAGGSTKGHTI
ALARAIQKQYNVPTVAHLTCVCADRSSIGAALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKENGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGIIVPIVPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNLSEILKA
>A0A6N8G5A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomonospora sp. PA3|TrEMBL
MVGSTTRNGSAPAAAPRPRDIRELLKTGEPTFSFEFFPPKTDEGLRKLWRVIRQIEALQP
SFISVTYGAGGGTRDLTVEITEQVATDTTLLPVAHMTAVNHSVRELRHLIGRFAGVGVGN
FLALRGDPPGDPLGEWVKHPEGLEYAEDLVRLLKETGDFSVGVAAFPYKHPRSPDIESDT
KYLVQKCRAGADYAVTQMFFDPEDYLRLRDRVAAAGCETPIIPEIMPVVKYSTIDMSEQL
SGAPFPRHLAAEFDKVKDDPEAVRKLGIEQAQRMCERLLDEGAPGIHFITFNQSTATREI
YEQVAADRLPAMAGARP
>A0A7C1I201|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
LETFTDVETLTAALIAVRKITSDMPVICEMAFSEYDRTGRATGDEAVRVMRQLSAHGADV
VGGNCGSGPTGLLPYIRRMAETSDMPISALPNASYPQYVDGRYVFRSTPEYIAERAEELV
EAGANIIGGCCGTGPEHIRLIAQRLNGRVPAIRRRVDRPSPLVELYERIERRPTGFFDDV
GDRSVILVEIDPPKGLDYAYVIEAAHALKRAGIDAMTSADNSLASIRMSTFVMSHLVQQE
TGLPVIVHCACRDRNLIGQQSELLGAAALGLRYILAITGDPASMANIGASSVYDTNSIGL
IKLIHTLNQGQNLAGAPTQRPTDFVVGCALDPSGHQMDGQLRRLAKKIEAGAQYVMTQPL
YDADRIRELYDRTRAEFPDTPVFCGVMPLASKRNAEFLHNEVPGIRIPDEIMERMRNAGD
EASKEEGITIAAELIETALEAGAPGIYLIPPFNKYEYALKLIPIIKAWDRKHRTATKR
>N9BUK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter soli NIPH 2899|TrEMBL
MSSLASYFQQRQFCVLVEYLTSLTPYHPLQTEIAGYPTVMALADRVHSDHDLAPLDASRT
YDSAVEKLLHFSGKDRDIQDFEAFLAQAKAANIQNLLLLSGDKLKSHSDGTDGRPRTRYL
ESVNAVAAAQHVGGFHIGVALNPFKYVEAERDAQYLKLHKKLKAGADFIITQLGYDIKAL
QQAKAFLTSHDYAQKIVACVMPLTLARANYMIKHKVAGIVITPHMLNVLKHEKQTGQTAH
VYARCALQILICEQLGFAGVHLSACHKPDEQARLAEYIEEYRHLDLAALEQHYNRLWHIQ
TGLELQPERLPSARKPSRLEMLKYRHLQFMHDALFMSKPAKNAGRFIFKAAFWNAHLMTK
MLLKTESFSKHRLVGCESCGQCRLADTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKVVEQTQILKDKLIPTVPIATRGSSSWKNWYLAVEA
>A0A6V8LLM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp. FSS-1|TrEMBL
MRIDDLLSRGKQFISLEFFPPKEKDAWPAFFYEAGRLSVLKPLFVSVTYGAGGSTQANTL
ELVTRFSRDLGQNPMAHLTCVGASEESLRSFMDALKAAGVDNVLALRGDPPQNQPDFTLE
GQAFQHGSDLAGFIRQAYPDLCIGVAGYPEKHPQAESLDADIDFLKLKIEKGGNFVITQL
FFDNDHYFRFVERCRARGIDAPVIPGVLPILNLASIKRILSMCGATLPPDYLARLEAANA
SGGAEAVRAEGVAYARAQCRDLLERGAPGVHLYTLNKAQACLDIAGDLKLG
>A0A0M2NLK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus pasteuri|TrEMBL
MSQFLKKLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVERIHRSYIEAGADVIQT
NTYGANFEKLKVFGLEHKVKEIHKAAVQIAKKAANNDTFILGTVGGFRGVKQDELSLSTI
QYHTENQIDTLVDEGVDALLFETYYDLEELTGIIVSTKRKYDIPIVAQLTASNTNYLVDG
TPINDALKHLVECGADIVGLNCHHGPHHMQRSFSHIELPNNAFLSCYPNASLLDIKNSEF
KYSDNAQYFGDIAQELIHEGVRLIGGCCGTTPEHINYIKTSVSNLKPVNHKNVIPIHKKV
NREKDISFKQSLTSKVKQGPTVIVELDTPKHLDTEQFFNNIGKLDDADIDAVTLADNSLA
TVRVSNIAAASIIKQRFNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEATKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITTHKEAIL
>A0A1C9V9T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp. PBC|TrEMBL
MNLPISFEFFPPKTPEGAEKLRAVRQQLYARQPLFCSVTYGAGGSTQEGTFGAVREILAE
GVDAASHFSCIGATRASVREQLAQLKGMGVKRLVALRGDLPSGYGLGGEFHYASDLVAFI
RAETGEDFHLEVAAYPEVHPQAKSPEADLKAYATKVKAGAHSAITQYFYSADAYFRFVDD
ARRLGADIPVVPGIMPIISSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIKSFGLDVV
TSLCEQLLRGGAPGLHFYTMNQSAATLEILRRLDTD
>E0Q6I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium dentium ATCC 27679|TrEMBL
MHSPLFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGRSSDRTLTARIAHTVS
EYGIPCVAHLTAQYLNKDDVDQALDMFDEAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREERPNLKIYGACYPEKHPQSATLEDDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KVRAVGIETPIEAGIMPVMNAKSVRRMAGICQSRVPEKLEVMLDKWGDDNAVLKEAGIAY
ASEQISDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A351M494|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides graminisolvens|TrEMBL
MKIIDLINSNEKTAFSFEILPPLKGTGIEKLYTTIDTLKEFDPKYINITTHRSEYIYKDL
GEGLYKRDRQRRRPGTVAVAAAIQNKYNIKTVPHILCSGFTREETEYVLIDLQFLGVTDL
LVLRGDKAKHESVFTPEGDGYNHAIQLQEQINNFNKGIFVDGTSMQNMEQPFSYGVACYP
EKHEESPNIEDDIYWLKKKVEAGAEYAVTQLFYDNKKYFDFVDRARQAGITVPIIPGIKP
FKKLSQLTMIPKTFKVDLPEDLTKEILKCKNDNEAQQVGIEWCIAQCKELIEYGVPSLHF
YTISAVDSIREVAQKIY
>A0A7I8MHY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis associated proteobacterium Delta 3|TrEMBL
MIVGDPKPIEEIAASIADFRKVLVFGCGSCVTVCRSGGDAEAHDLANQLSHPRYFISAPP
QLEVHTIERQCERDLLEAFLKLPDGIDAILSMACGVGVQVVSDMVDPMPVFPALNTTFMG
GADEPGVWREKCRGCGECLLAYTGSICPITRCAKSLLNGPCGGTGNGNCEVDPYMPCAWA
MIYYRLKRQGNLDLLKKIRTSQDWRAAGSQGPRVRKRPGIGK
>N9AFS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter soli NIPH 2899|TrEMBL
MTKRVPISFEFFPPKTDIGAEKLITVHQDLQQLQPEFFSITYGAGGSTRERTLAAIKEFN
GKGTPVAPHLSCIGDDKARIAELLDLYVAQGINKIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAETFDQDIQRFTEKVNAGANSAITQFFFNPDAYFYFL
DRLQKQGITIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSRSIRAFGHE
VILKLCERLIDGGAPSLHFYTMNTTEPTRQLVVDLGLN
>W4V4C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetivibrio thermocellus JCM 21531|TrEMBL
MLKQKIINRESGIITYGITPPKKNNTEEKIKEISQKHIERIKGLDIDGLVIYDLQDEKDR
IAEDRPFPFMETVDPQTYSENYLNALKIPKIIYRSVGKYTPDEFIHLIRPVPGQDAFSVF
VGAASRNQSVLLKLSDAYKISQDTNPDLVLGGVAIPERHMKNTDEHLRIIGKINKGCKYF
ITQAVYNVEAAKDFLSDYYYYSKNNNLAMVPIIFTLTPCGSTKTLEFMKWLGISIPRWLE
NDLMNSEDILNKSVSLSKSIFNELMEFCLEKGIPVGCNIESVSVRKVEIEAQLI
>A0A1V5PTX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium ADurb.Bin346|TrEMBL
MSEELKSTNGSNSAISRLPLKEAMANGDFAVTCEIGPPKGVDTAEIYEVGEILKGLVNGI
NVTDLQSSVMRLGSLAACHMLKDMGHDPIFQMTCRDRNRLALQSDLLSAYALGIRNVLSL
TGDHTTTGDHPQAKPVYDLDSVSLLYTMSKLEEGLDLVDNPLKGKPSFFKGAVVNPGADT
DASLNLQLMKMQKKIDAGAQFFQTQAVFDERVMEKFAIKIEKLGIKVPVMAGVILLKSEK
MANYMNKNVPGIFVPKNIIDRMAATTDKVSMCLEILTELITRLKPYCAGVHIQALGWEKH
VPALIENVGI
>A0A5M4D4X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium CYA|TrEMBL
MHIRDIFSKVRTTFSFEFFPPRDESAAGELFENIAELEQLKPTFVSVTYGAGGSTRELTR
NLVVRIREETGLDPVPHLTCVCQSQSDIEQILRRYAEHGISNILALRGDPPKDRGDYDPK
QDAFGYASGLVSFIRRFGEGGGHPDRRGFGIGVAGFPEGHPQTPNRLLEIEHLKAKIDAG
ADYIITQVFFENRDFYDFRDRCRLAGIHVPIIAGIMPITSMPGMKRMAELALGARYPAPL
LRALARTDGKPENVRRVGVHWATEQCRDLLDHDVAGIHLYTLNKSTATREIYRTLGVQDS
RALQQ
>A0A6P5D470|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos indicus|TrEMBL
MDRPKPKVFPVGHCCPSLGMRASEAGSGRFSVPPSISRNSAMVNEPRGNGSPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLS
GEPNQNGXKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>A0A7I6HB59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O9:H4 (strain HS)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0Q9NF38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Soil750|TrEMBL
MKLDLRAALQQEILTGDGAMGTYLYQMGFPVGISYEELNLLRPETVADVHRRYFEAGARL
IETNTFSANREKLSKYGLEGDVEAINRAGVELARNAVGDDAYVVGAIGSIRAGKRKNVRT
SEVEQSLREQIGILLDSPVDGLLLETFYDLEELQLALRIIRSMSGLPVICQFANEGTGST
QDGVPLQEAFLRLRDEGADVIGFNCRVGPNGILRSMEKIAPIPGIPFSAFPNAGLPDYVD
GHYTYTATPKYFAESALRFADLGARIIGGCCGTTPEHIAAVAKALQGYVPAAPGAAPVGA
AAIVIEPAPAKPAPPAGIPSLLDIVKQRKTVIVELDPPKDLDIEKFMQGSKALQDAHVDA
ITMADNSLAVTRMSNLALGYLVQERLGARPLIHIACRDRNMIGTQSHLMGLHALGIDHVL
AVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFVVGAAFNPNV
KHLDKAVQRLERKIEAGADYIMTQPVYDAKLIEDIYEATKHLQIPIFIGIAPLASGGNAE
YLHNEVPGIRLSDEVRARMDGLKGPEGRAMGVEIAKELLDTAMQYFNGIYLMTPFLAYEM
CVDLTNYVWEKSKRHDFHLYPLSK
>A0A4Q6FZ98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium|TrEMBL
MAGVPVSFEFYPPKTDEQRTQLDRTAEKLKAHSPEYVSCTFGAGGSTLSYTSETVRHLNQ
SHGFDAAPHLSCVGGSREEIRELLRLYRALGCKRIVALRGDLPSGMGHPGDLRYASELIE
FIRAEHGDAFHIEVGAYPETHPQSDDALVDLRHFKAKVDAGADGAITQYFYNADAYFHFV
DEVRRLGVGIPIIPGIMPISNYSQLRRFSEACGAEIPRWIGKRMQALGDDAEGIREFGAD
VVAGLCRRLIEGGAPALHFYTLNLAKPTNAVLARLP
>A0A4R2RH85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum bhavnagarense|TrEMBL
MSAPRVSFEFFPPQSLEASFRLWETVQALAPLKPGFVSVTYGAGGTTRQLTHEAVETIHT
HYGLNVAAHLTCVAASRDETMEIAAAYAKAGVTEIVALRGDPPKGQGQFTPHPDGFANSC
ELVAALAETGKFKLRVGAYPDPHPEAKAPGADVRWLKRKFEAGASSAITQFFFEADTFFR
FRDECEAEGIDGSKIIPGILPIEKWGGVRRFAERCGAHIPGWVDQAFETARRDGREEMLG
QAMATELCSQLMEGGVRDFHFYTLNKPHLTRDICHALGVQPDGHLEKVA
>W7PYU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. BC04|TrEMBL
VVPHLAARLVRDRGHLKRLLARLAELGVEDAFVVGGDAERPVGXFPHGLALLEAMAQLSM
RPERVGVPAYPEGHHHIEAASLQRDLEAKAALADYAVTQLCFDPGPLLAWRERQRRLGLR
LPIYAGIPGVMERKRLISIALRLGLGPSVRALRRQGGWMTRLFGPAVYRPDVLLRSLWPC
LGKGNTGFVGLHVYTFNQVGPTRAWLETLPSSRATTLTSRA
>A0A1J5HV96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium CG2_30_49_12|TrEMBL
MTISFKETLASGKFIVTSEVGPPKGTNLEKMIHHIALLKESVAAINLTDHQSSIMRYPSL
GAALLVKEQGGEPILQMTCRDRNRLALQADLLFAYSRGIKNVLCLTGDSLVVGDHKEARG
VFDLDSSQLLAAIRTLEKGKDMGGNDLDGTVSFCAGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVYDLDKFRDFMSYARQFPVKILAGIILLTSAPMARYMNKNVPGVRVPQELID
EMAAAPKGSTLSKGIEIAGRMIREIKDDRICDGVHVMAIGKEEVVPEILKEAGL
>A0A4Q6FSZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium|TrEMBL
MRPISFEFYPPKTDEQRAQLDRSVQKLKAHAPQFMSVTFGAGGSTLSHTPETVQRLRSEH
GVAGVPHITCVGGSREEIRSLLKLYRALGCDRVVALRGDTPSGMVRSGDLRYASELVELI
RAEHGEHFHVEVAAYPETHPQAEDAHVDLRNFKTKVDAGANGAITQYFYNTDAYFRFVDD
ARALGIHVPIVPGIMPISNFSQLKRFSEACGAEIPRWIGQRMRAYGDDAESIREFAADFV
AKLCERLIAGGAPALHFYTLNLAKPTLNVLARIG
>F3UV40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis SK49|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTFAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A3M0HP65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. SBT000017|TrEMBL
MSEESVRGRSSRGFVTRTPSIVDRLRTEPEARIPFSVEFSPPRDAAAEARLWRAVREFEQ
LQPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRG
ITNILVLRGDPPGDPLGDWEKHPDGVEYAEELVRLVRDLGDFHVGVASFPEGHHRAADLE
QDTRCLVGKLRAGAEYSITQMFFDVDDYLRLRDRVCAFDAEQGAKPIIPEIMPITSLRSV
RRMLELSGTTLPSHLDEKFTRAAGSGPEEDRAAVREVGIELATNIGERLISEGAPGLHFI
TLNFARATREVLSNLGLAAARV
>A0A7Y2REQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter terrae|TrEMBL
MLVEYLCSMKEILPVKTEFAGFPALMTLADRVHSDDDLAPIRAAQAYPKSVEKVLHFAGK
GRDIADFEHFLNEAQAVGQQNLLLLTGDKLKSHQYGQDDITKRTRYLESVNAVMAAKQRG
GFCIGVAFNPFKYTEAERDAQYFKLHKKMKAGADYIITQLGYDLSALKEAKAFLTQHGYP
QKLLACVMPLTLARANFMMKHQVAGIVITPHMLNVLREEKEAGLMDRVYLRCALQILICQ
HLGLAGIHLSACHKPEEQMLLESYIEEYRHLDLAELELLWNTLWQVKTGQEFYPELTYYS
RPASATQIFKYQHLHFMHDALFESKVAKGVGRFIFQSRFWNGTLAAQALLKTEFVSKHGV
VGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVNQ
TQVLKEKLIPTVPIEVRGSSSWKNWYLKKAV
>A0A256YY54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon ex4484_40|TrEMBL
ETIYQITCRDRNRIAITSDLLGAGALGIKNVLALTGDHTTLGDMPQAKPVFDLDSVQLIH
MARMMVDEGVDVSGNEIKDPPKFHVGGGPLNRNS
>A0A0G4NHI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium longisporum|TrEMBL
MDEFVDWDKAGDNVGMLLDDTGPLPPSPSEPIPTNIADQDIDLMLANVDDDDFSFWALQH
FSEAGQEGQDAPLGSASAASAFQMDLSAGPVPEPDQLPNPLPDFFWYRPAVPCTSCSRSG
LECKRIREGEYKGFCTSCVALWCPCSFAPSVPANNWSNDLSEDPVVTNDKDVPSSQSLLK
ASLSSAPLEMAPPPIVPPVHENTAAAAAGAAVPNKNSPPPKIGARFSRESVKILKTWLSG
HNRHPYPSDEEKEMLQRQTGLNKTQITNWLANARRRGKIQPPRSTSPATHTLYAGAVDIP
RRPGTPAFDKSIANKNPLERWVDSPPDNEPASVTAIARAVASNSDMSSGSGLNSPHSFAF
TDDGSGRSLVDYSSTSSVGTSSGGSFASVYSHASRGSFGSFSSMQIRGRRRRRRRAAPQR
GPDDKTNLAAPFKTFQCTFCTETFRTKHDWQRHEKSLHLSLERWVCAPNGPRALNPATNQ
VSCVYCGEVDPDNEHIESHNHTTCQERSLEERTFYRKDHLNQHLRLVHNVKFMDWCMKTW
KVATPEIRSRCGFCGIIMDNWSIRVDHLAEHFKTGNTMADWKGDWGFDAPVLDMVENSIP
PYLIDHERNTPFPYVAGGSPPESPRSAYELIKMELAFFMMNHEDKTGALPNDDEMLLEAC
RIIFASEVLSLQGIDSNFSWLRDLFMSSPEVARQAQFGPLRSAIENRLSILKINGKDNLF
EACPLEKQLRDFVSSRTLLGLTPIDDELQVEACCIVGRIEEASTTPSDFIANWLVRFINS
STGWLANFRQRAHLPRTEDIKNAYFRSTDTTKIDSTIHIYSRLETSLSEYMEDQRVLGIE
PTDEDLQRRARIIIYEFDDGWNQTAADSLVWLTAFRERHPPGGSSSQTQDSLMLNASEPA
LIVLGLQQQLHAPQADTQTATSPPQPSFSAASREFVSSPPRSKHMGGATCMNDSNRFRRL
ARELRRFVTQTTSPNNPNQHVPSDQELQHQARWIMYDDDDPWNQTPADNAEWLQRFKRDA
GLLAAASPLDPNQNVVPSRTMAEAAASSCPFNPKIDFSTPFSTSTTLAGTSPFMRRAKHM
NCSVPQEFMDALEPVKNDDNAVREVGKVLVAGMCRKILAAGIHHLHFYTMNLAQATRMVL
EELNWMPTSERPLKQALPWKQSLGLGRREEDVRPIFWKGRNKSYILRTQDWDEFPNGRWG
DSRSPAFGELDAYGIGLTGTNEQNIKKWGEPQTVQDIATLFVRYLQNEIDCLPWSESPLT
NEADPIREDLIALNKRGIITINSQPAVNGVKSSHAVHGWGPKNGYVYQKSYLEMLVHPDL
YPEIISRIEKHPDMTYYAEKWVAADGGFEYARDLVKHIRATYHDHFDIGVAGYPEGCDDN
KDEESLLDHLKEKVDMGATFIVTQMFYDADNFVRWVGKVRERGITIPIVPGIMPIATYAS
FMRRAKHMNCSV
>A0A7X2ZHU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus timonensis|TrEMBL
MKPDLRTTWEREILVGDGAMGTYLYQLGFPVGISYEEFNLLRPDVIGDIHRRYLDAGARL
LETNTFSANYYKLSKFGLEAKVEDINRAAVRIAKQAAGDRAYVAGAVGSIRGGKRANVTA
QELGSYFEQHIAALLTEGVDALLFETFYDLEEMRIALGRARKLTDIPVICQFAVDQIGRT
LDGFTIPEAFGALVQEGADVLGFNCHSGPKGIMAVMAGVGGPLEVPMSVFPNAGLADYVD
GEYVYGATPEYFGECARSFADLGARLIGGCCGTTPEHIAAMATALEGYAVAPLANETKLP
EPRSSVAVTLKERPTTATAGIDGEDRDLSSLTELVKQRHTVIVELDPPRDLDIGKFMEGA
AALKEAGVDALTLADNSLAVTRMSNMALGHLVQSQLGLRPLVHIACRDRNLIGTQSHMMG
FDALGIDHVLAVTGDPARFGDLPGASSVYDLTSFEIIRMIKQLNDGISFSGKPLKQKAKF
VVGAAFNPNVKHLHKAVERLEKKIASGADYIMTQPVYDRELIVAIKQATAHLDVPIFIGI
MPLASGKNAEYLHNEVPGIQLSDDVRKRMEGLQGEEGRAMGVEIAKELLDTAMEHFNGIY
LMTPFMFYEMNVALMNYVREKSKPSSAHLSRFT
>A0A1F2VJ21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium RIFCSPLOWO2_12_FULL_67_14b|TrEMBL
MTPFQPVKPFLEALDERVLVCDGAMGTMLYAKGVFINRCFESLNLSQPGLVVDVHQDYLR
AGADVIETNTFGANRMKLRAFGLGDQVRDINLAGAALARKAVEQSGQRAYVAGAMGPLGV
RIEPWGKTGVDEAEAMFREQAQALLDGKVDLFVLETFRDLNEIGAAIAAVRAVCDLPIVA
QMTTEEDGASLDGAPPEQFAPALIARGANVVGVNCSVGPAPMLETIDRISEVTDVWLSAQ
PNAGKPRDIEGRNLYLCSPEYMASYARRFIASGVRLVGGCCGTTPEHIRQISLAARSMAP
GLARHHGGTPEVRTPVASQPNARPALPREAKSTMARKLVNGGFIRAIELVPPRGHAPTAA
LADASRLKARGVDVVTIPDGPRSGARMSALSLAVLVQQHAQVEALLQYSCRDRNLLGIQS
DLLGAHAMGVRNLLGVTGDVRTLGDIPDATAVFDVDSIGLTNVITRLNHGLDIGGQSIGE
PTSFHTGVMVNPSRDLDQELRRLEFKVEAGAEFAVTRPVFDVSAFERFLARVSGLGIPII
VGIWPFESAINAEFMANEVPGVTVPDALVERMRRTSSAEQARAEGVKVAQELAEAMKDMA
AGVQIATPSGRLDAALDVLDVV
>A0A212QVB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoflexus hugenholtzii JAD2|TrEMBL
MISKPSLLERLARGPVLADGAMGTMLYARGFSFDRCYEALNLEAPDVVREIHRLYLEAGA
EILETNTFGANRYRLAEHGLEDQVARLNRAGVELARQAASAAGRPVWIAGSVGPLGVPLA
PLGRVKAVEAREAFREQIAALAEAGVDLLILETFSSLPELVEAVRAAQEVAPHLPLVAEM
TFAQDGHTLMGHTPEEVVDALMALGVPLIGANCSVGPAKLLPVIRRMAARVREAGGPPPD
LVVMPNAGWPEMAAGRLRYPATPDYFADYARRFLALGVRVIGGCCGTTPEHIAAIRRTLS
AHPEPAPEPQPVILMPPPPPAPMEQPPTELARRLRSGRLVISVEVDPPRGPDASGLLEVA
RSLKAGGVDVLNIADSPMARLRMSPWALAFLVQNHVGMETILHFPTRGRNLLRIQSDLLA
VHALGVRNLFIVMGDPPAQGDYPEASDAMDIVPSGLVRLIKERFNAGQDHAGEPIGRPTA
FFVGVALNFNAPDPAREIKALRRKVRAGADFIMTQPVYEPEALRAFLRRYEEEAGPLSIP
ILAGVLPLVSLRHAEFLHNEVPGIMVPEAVRERLRRAGEERARGEGLRIAQEVVAELAEF
VQGLYVMPPMGRYELVFSLMEAIPPHRRGGGRTGEPAMESEGPQVSGGRGELSDER
>A0A0G4L765|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium longisporum|TrEMBL
FDIRPSKYTRSTSRRVQIDMDEFVDWDKAGDNVGMLLDDTGPLPPSPSEPIPTNIADQDI
DLMLANVDDDDFSFWALQHFSEAGQEGQDAPLGSASAASAFQMDLSAGPVPEPDQLPNPL
PDFFWYRPAVPCTSCSRSGLECKRIREGEYKGFCTSCVALWCPCSFALSVPANNWSNDLS
EDPVVTNDKDVPSSQSLLKASLSSAPLEMAPPPIVPPVHENTAAAAAGAAVPNKNSPPPK
IGARFSRESITNWLANARRRGKIQPPRSTSPATHTLYAGAVDIPRRPGTPAFDKSIANKN
PLERWVDSPPDNEPASVTAIARAVASNSDMSSGSGLNSPHSFAFTDDGSGRSLVDYSSTS
SVGTSSGGSFASVYSHASRGSFGSFSSMQIRGRRRRRRRAAPQRGPDDKTNLAAPFKTFQ
CTFCTETFRTKHDWQRHEKSLHLSLERWVCAPNGPRALNPATNQVSCVYCGEVDPDNEHI
ESHNHTTCQERSLEERTFYRKDHLNQHLRLVHNVKFMDWCMKTWKVATPEIRSRCGFCGI
IMDNWSIRVDHLAEHFKTGNTMADWKGDWGFEAPVLDMVENSIPPYLIDHERNTPFPYVA
GGSPPESPRSAYELIKMELAFFMMNHEDKTGALPNDDEMLLEACRIIFASEVLSLQGIDS
NFSWLRDLFMSSPEVARQAQFGPLRSAIENRLSILKINGKDNLFEACPLEKQLRDFVSSR
TLLGLTPIDDELQVEACCIVGRIEEASTTPSDFIANWLVRFINSSTGWLANFRQRAHLPR
TEDIKNAYFRSTDTTKIDSTIHIYSRLETSLSEYMEDQRVLGIEPTDEDLQRRARIIIYE
FDDGWNQTAADSLVWLTAFRERHPPGGSSSQTQDSLMLNASEPALIVLGLQQQLHAPQAD
TQTATSPPQPSFSAASREFVSSPPRSKHMGGATCMNDSNRFRRLARELRRFVTQTTSPNN
PNQHVPSDQELQHQARWIMYDDDDPWNQTPADNAEWLQRFKPAQWPRRRHRAAPSTPRLI
SRHPSARDAFFATFDTRHARPGTIFCARELEDSLVGFVHSEAAAGREFPRDEALRAKARE
VMGAVRTAADDETLLGKFKAWVVAEIAGEGEQQRQAFTDAEIEGMLAEMEMEYGGEIGGG
ASLLVGTWRGGALGSPYHKVQRRTQQHLRVPKRAMGSTSVDTVAQSSNATYNRPKTRQRV
HKAPPVLDVPDIDEDAAERKRVLNVLAQRRYRERKREARTKSKDSKPRDDLSTVDGIRPA
SSSHPDGSASSVSPSDAPRTSVPPNDLLLTSDLDLDLEMPWDPVSLEPTSVSTLAETFPC
VPFETIMWDSLSPPSSSSPAGSSSGFSSNLISNSTAISSSNRSNLGTPATSSPGEPFAPP
VPVDDFTDRYLLPMADLTLLRAFLSIADRLGCASELWSPTSNSPFNKGGGTPAALLPPSF
RPTPTQVQLPHHPMLDFLPWPSVRDRIISIFNMPEAMRPPGARDALAPIKFAYDLEDEAE
GVRIWGGDPYDATGWEVGQTFFERLPIPPNPTATMHIKEMLADAERDGQPSFSFEYFPPK
TAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIAELTCEMVTQAQSVYGLETCMHLTCTD
MGLEKVNDALRKAYKAGCTNILALRGDPPREKEKWVAADGGFEYARDLVKHIRATYHDHF
DIGVAGYPEGCDDNKDEESLLDHLKEKVDMGATFIVTQMFYDADNFVRWVGKVRERGITI
PIVPGIMPIATYASFMRRAKHMNCSVPQEFMDALEPVKNDDNAVREVGKVLVAGMCRKIL
AAGIHHLHFYTMNLAQATRMVLEELNWMPTSERPLKQALPWKQSLGLGRREEDVRPIFWK
GRNKSYILRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEQNIKKWGEPQTVQDIA
TLFVRYLQNEIDCLPWSESPLTNEADPIREDLIALNKRGIITINSQPAVNGVKSSHAVHG
WGPKNGYVYQKSYLEMLVHPDLYPEIISRIEKHPDMTYYAVTKSGNLKYNAPSDGPNAVT
WGVFPGKEIVQPTIVEGISFVAWKDEAFRLGLDWAHCFEQSSPSLNNDFHQQREIFDLFE
GLSVKEYDDIKPVVKDVAPDAVSAPTNGTTNGIAVPAA
>J3FR37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM33|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLALYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A2N3Y1B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora spinosa|TrEMBL
MTSGQLSPRRAVTPPAAVPAQRTTRPRTVRDRLAAGTPVISLEFMPPRTTNDADRIRRNV
RKLESLRPGFVSVTYGAGGSTRDNTIDVAAWIAQDTTMLPVVHLTAVDHSVQELRSFAGA
LADAGVVNVLALRGDPPGDVTGEWVRHPDGLTYASELVTLLREHGDFCVGVAAFPHRHPR
SISVEGDTAHFVAKCRAGADYAITQMVFDADDYLRLRDRITAAGCDTPIIPALMPVTTMK
TIARSEQLSGAPFPPHLAERFAAVADDPAAVRALGIEQAILLSQRLLAEGVPGLHFITFN
FARATTEVVAELALATS
>A0A3A5M6K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter cheniae|TrEMBL
MSSPTYPALSYELYPPKNAEADDSLWTTIRRLEDTRPDFVSVTYGAAGSNRETAIDLLRR
LLTETTLKPLAHLTCVGSSRAELTDIIDRLIGGGVRGILALRGDAPDGVDTHSDDVEHAD
DLVRLIREVEARRTAQLAAGKVSVGVAAYATRHPDSPNLEQDIEVLLAKEEAGADFAITQ
VFFQPSDYARLVDRADRAGVTIPIIPGIMPLTSTRRLKKAGALAGIDVDQDLWARLEGAR
TDEERRTVGVSATVALARAALDDGAPGIHLYTFNEHAAALEVLDALDLERPPEAGLAASL
>A0A0M6ZQD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium album|TrEMBL
MSEFSNRRSHQAALSPITASFEFFPPKSDKMAETLWGTVKRLEPLSPSFVSVTYGAGGST
RERTHKTVERILGETDLSPAAHLTCVGASREEVDAIIEDYWKLGVRNLVALRGDPLEGIG
SRYVPREDGYAYASDLVAGIKKIADFDISVSGYPEKHPESGSWQSEIDNLKRKVDAGADR
IITQYFFDNDMFDDYLDRIAAAGINVPVIPGILPIHNFEQTMVFSAKCGTSIPSWLARRF
AGLHNDPETRKLVGVAIACEQVMDLVDRGINDFHFYTMNRADLTYAICHMLGMGQQAPEN
MAA
>A0A6N7F652|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTAATGPVEDMKHMLAEKMPAELPFPARRPADLRISFEFFPPKTEKMAETLWNSIKRLEP
LSPRFVSVTYGAGGSTRERTHATVTRILNETALKPAAHLTCVNATREEVDEVARSYWEGG
VRHIVALRGDAPDAAAGYRPTPGGYAYAADLVEGLKKVADFEISVAAYPETHPEAQSGEA
DLDNLKRKLDAGADRAITQYFFGAEVFLRFLDRARKAGITAPIVPGILPVQNFAQVCKFS
GMCGTEVPGWMGELFEGLDDDPETRSLVAATVAAEQCRQLHAHGIDEFHFYTLNRADLAY
AISHVLGLRPAAGGRTDTTVKES
>E0SGD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya dadantii (strain 3937)|TrEMBL
MSFFHANHQEALNQNLAELQGRINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRSELSYAICHTLGVRPVTAA
>A0A7C7J4P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTDSDAGTLDDSRSTHSQGRLERLLQAGAFVVTAETTPPVSTDPAALLEVTEDLRDWADA
VNVTDSAGAKSHMASLAAASLLMRAGIEPVLQFTVRDRNRIALQNDLLGAGALGISNILC
LTGDNILAGDQPDAKMVMDLDSRGLVSLARDMRDSRQLPTGRPIGKAPNLFIGATDAPQE
PDNEWSATALQSKVDAGAEFFQTQFCFDIDLVRRYMERLENEGVLERAYFLIGIGPIASA
KSARWMNQNLFGVDIPESIIGRLEQATNQQAEGRRVCLELIQQLREVAGVSGVHLMGPQA
ERSAAQVIADSGILNERPEVA
>N8V4J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 3789|TrEMBL
MSALSHYLQQQQFCLVLEQIVSKRTELPPISTLAGLPCVMAFADRVHADDDPSPITLAQS
VRTDQAKLLHFSGKTRDVKDLQQFVEQAKQQNMRDLLLLTGDKLKQHNFGKQDPRQRTRY
LESVSALMWVKAHAPDMSCGVAFNPFKYTESEEQAQYLKFEKKQRAGTDFVITQLGYDLN
KILKFKQFVDASIQPCPVLACVMPLTYRRAKFMVKQQVAGIEISPHLLQHLKAEQQQNAA
WAEQRVYARAALQIWIYRHWGLAGIHVSGCQNPEQQALLEQALAQYQTWTLEQCLMEWNH
LCKIVRGDEMQPDLSTAYPQQQPSVLKYQVLQVTHDWLFDSALAQKIGRFVFQLGFWQQG
LAAKSILAVEYVSKHAAVGCESCGQCRLAETLYICPETCPKGLANGPCGGTRLDRCEFTD
RECIHSQKYRLAKQVGQQDILRRELIPAVPVELRQTSSWVNWFNPKSH
>A0A4R5Z0T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus dendritiformis|TrEMBL
MKDLRQVLQGEIIVGDGAMGTYLYQLGYPVGISYESLNISEPERIRDIHREYVSAGARLL
ETNTFTANREKLSKHGMEKQVKAINRAAARLAREAAGGQAYVVGALGSIRAGKRENIETD
QVKRDYTEQLSALLEEGVDGIMFETFYDMEEMKLAVQIVRALDDRIPIICQFAVEESHRT
KDGLRLLDAFRLLREEGADVVGLNCRMGPNGLMRAMEDLTGRLALPMSAFPNAGLPDYVD
GRYNFVATADYMAESAVRFAELGARIIGGCCGTTPEHIQAIAQALANVQAPALPTLAEEE
AQAQAVPPLEIGERGAAPASGQGKAASGPSLVDTVRERHTVIVELDPPRDLDIAKFMLGA
QALKDAGADALTLADNSLAVTRMSNMALGYLALDKIGIRPLIHIACRDRNLIGTQSHMMG
LDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEIIRMIKQLNAGLAFSGKALKQRANF
VVGAAFNPNVKHLNKAIERLERKIEAGADYIMTQPVYDASLIERIAEGTKHLNVPVFLGI
MPLASGRNAEYLHNEVPGIHLSDEVRERMKGLEGESGRREGVAIAKELLDVAMKHFNGIY
FMTPFMFYEMTAELTEHVWQKAERLTDPLYRHT
>A0A8I3MEZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Canis lupus familiaris|TrEMBL
MVKEPRGDGDGGPTPRSEGSSSGSESSKDSSRCSTPGLDPERHERLREKMRRRMESGDRW
FSLEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLV
RHIRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHF
VKACSEIGITCPILPGIFPIQVLQLVLTISAPWEPLALMLTRLSVNTPRGGRAGMLWQLL
YSVEGKQQDKGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELL
TSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASR
PKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEES
VFEVFARYLSGEPNQHGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNING
KPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITN
APELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQ
YIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLKGPSPEREAEAV
>A0A6N7FC67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSSRAAAPEPPGTSIVTDDIAYPADSGLARAIRAGAFALTAELVPPVSGAPEPLRAAAAP
YKGILDAVNVTDGPRAQVHTSGLAVAGLMVRDGIEPILQVTCRDRNRIALQMDLLGASAL
GVRNVLLMSGDRPEEGEDAPKPVFDVGTEELIALAAAMREGGALPSGRRIAAPPRLFIGA
ADMPVDPRPGWKPDGLMRKIDAGARFVQTQLCYDIGVVRRYIAALNDAGVTGRAAILIGL
GPLASARSARWMRENLYGVIVPDALIDRMERAADQKAEGIAVCAELLAELAGIDGVAGAH
LMAPANPDCIPATVERARLGPAFR
>A0A3D1GTJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MAVSIDNLASAGQEWSIEVTPTGATKIDSFAACLPEGTTVNVTFLPGTDPLDTIAVARRL
ADDGMNAVPHIAARSLKDADQLDDLVSRMTSEANVSEVLVIGGGVDKPVGDFDSSMQVLQ
TGILQKYGITRIGVSGHPEGSPDIPDDALASAIAWKNDFAAKEGLSLYMETQFCFDAETV
LAWERKIRADGNKLPIRIGIPGPATIKTLFRFAQISGIGPSMRFVAKQARNVAKLMTVQA
PDLLLAGLAEGMASEKGCLLAHFHYYPFGGFAKTAAYAQAVATGQIDLTAKGGFDVRQAS
>B8M3Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MHIGQKLQEQETSGRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRS
ELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALESAYNAGCTNILALRGDPPREQEK
WEAAEGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
IVTQMFYDVDNFLDWVSKCRAKGIKAAIIPGIMPISTYDAFMRRSNWTKIRIPPDWLDKL
EPVKADDAKVREIGTKLVAEMCRKLLASGQIHHLHFYTMNLAQATRLILEELRLLPSEEA
PLHKPLPWRRSLGLRRRSEDVRPIFWRNRNASYIARTADWDEYPNGRWTDARSPAFGELN
AYGVRLKGTNEQNIKLWGAPKSIKDLSDIFVRYLNGKVERLPWSDSAVTPETSDIQNELL
DLNKRGFLTINSQPAVNGVKSTDPVHGWGPRNGYVYQKAYLELLVPPEHVDELLRRIEKN
PDLTYYCVNKTGELKARSDEGPNAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQLGEDW
AKCHPADSPSRKLIQRVMDEWYILNIVNNDFHKNDDIFRLFDGLVIKDFETEVPGSAPEV
VTNGTTN
>A0A3C0TWY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTLPPEPSGPAWILPQKEGAPARALNVSFEFFPPKTQEMEEVLWRSITRLAPFRPKFVSV
TYGAGGSTRQRTHDTVRRILQETDLTPAAHLTCVGATCDEVDQVISDYWEAGVRHIVALR
GDPPEGQSKYSPHPGGYAYASDLVAGIRRIGDFEISVAAYP
>D8A9M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli (strain MS 21-1)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1Y0Y5I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter pasteurianus subsp. pasteurianus|TrEMBL
MSLSRLSVELIPRSAEALATDVATVKATFSVADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQPGLEEILVVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMQGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLDANIQFAQTVLKELAQEKGKAYLMPVRIKLEQY
LPHLLDAVA
>A0A5C6ZVF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gillisia hiemivivida|TrEMBL
MKITEHIAAAKGKTLFSFEILPPLKGQNIQSIFDGIDPLMEFKPPFIDVTYHREEYVYIL
QANGFLEKKVVRKRPGTVGICAAIQNKYGIDAVPHILCGGFTKEDTENFLIDLDFLGIHN
VMALRGDAVKSETYFKPEPKGNNFASDLVNQISEINRGQYLDNHLEKNHTTDFCVGVAGY
PEKHMEAPSLDNDIEKLKAKVAAGAEYVVTQMFYDNSKFFEFVEKCRKSGITVPIIPGLK
PIATKKQLTNIPHRFHLNLPEELISSVNNCKTDLEVREVGVEWCTAQSKELISSGVEVLH
YYSMGKSTNIHKIASSVF
>A0A0B0D7G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria marina|TrEMBL
MPAPLAASEPAPVTGPPTGTSWLVRRPRRSTLVSFEVFPPRPTADPDTVWRNIDAMAQAG
PDFFSVTHGHAGHHGVSREALRHLRRTTKTPVMAHFTCGGTDRAGLERAVDQLLDDGVRD
LLALRGDPPLGTGEWRTPAGGLGRASQLVELIRDVERRRFGTGFRPGQRPLSVSVACYPS
PARGRDFEADLASLWDKQEAGADYAITQVLYEPEDYATFLERARSEGIHIPVVAGLMPLS
NPQRLQRMTEITGVRVPERLTRFLRADTPEELRHRGVAATLSLIDDLMDLGCAGFHLYTF
NRPEAALTILEHLRVRDAAREYRGRSPAA
>A0A1E4KTJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium SCN 69-123|TrEMBL
MPSLSFEFFPPKTDEQRSQLDRTAEKLKEYAPRFVSVTFGAGGSTLSYTADTVRGLHDQH
GLDAAPHLSCVGGTREEIRELLQRYREIGCRRIVALRGDLPSGMARPGDFRYASELVEFI
RTETGEHFHIEVAAYPEVHPQADDALADLKHFCTKVRAGANSAITQYFYNADAYFAFVDA
VRREGIDIPIVPGIMPISNYSQLRRFSEMCGAEIPRWMAKRMQAYGDDAAAVREFGADAV
AQLCRRLIEGGAPELHFYSLNLAKPTLAVLERLG
>A0A537RZ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MLPIPADDAPSPRAAADAQDIAATAAELVACGSLEMGADAPEDAQRIAALLPAGTPVYVN
HLPRRELAHTLPALVALSEAGLEPVPHVAARRIVSRAEVEAFLKQAVRLANVRKVLLIGG
DVAEPLGPYVDGAALMRDGLLPGCGVQQVGLPGYPEGHPRIASATLAAALAEKLALARAQ
GLGAYVVTQFSFAPNRIVEYCADLARRAADVPVYVGLPGPTSPRTLLRYAQRCGVGASLR
AL
>A0A4R9JMA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira kemamanensis|TrEMBL
MNKILLEVVPREIPVILQEVNFVKKNFSQISGINIPDLLRFENRSWSVASLIQPIYPNVI
PHLRAIDFDLDHCEEIIDTLKQSQISSVVVIKGDPPTDMSKRVYPTTSIKFIKKLKKEIH
HLKVYAAVDQYRVGIKDEFDYIEMKKDVGADGFLTQPFFDMRLVDIFTEKLKGMEVYIGV
SPVVTEKSQSYWESRNRAYFPKDFVPTIDWNVKFAKEVITFCSKNGMNTYLMPIRIHLEE
YLRRIFD
>A0A447TQI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MNCAPSPATTGITVSATLSLCAAILPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVH
PEAKSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSN
FKQAKKFADMTNVRIPSWMSLMFEGLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYT
LNRAEMSYAICHTLGVRPGL
>A0A7C6D1A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MTDCRSNLQRVLDSGNFAVTAEIGPPKSASGEAVQRRARLLKGHADAFNLTDNQTATVRL
SSMASAVLCMQEGVEPVLQMTCRDRNRIALQSDLLGAASLGIRNILCLSGDHPRFGNQKG
AKGVYDLDPVQELMVFRMMRDEGKVWGGDTLEQAPQVFLGAVANPFADPLDLRAVRLAKK
VDAGAEFVQTQAVFDLDRFERFMKQVRERHLDERAHILAGVIPLRSAGAARYMRDRVPGM
SVPDEVVDRMSKAADQRDEGIEICLETIERLRSIEGVHGIHIMAIGWEDIVPEIVDRSGL
SQRP
>A0A816QF46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica napus|TrEMBL
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNAICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAYGIHFATEMCKKILAHGITTLHIYTLNVDKSAIGILMNL
GLIDESKITRSLPWRPPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYSTLSDYQFMRPRARDKKLQQEWVVPLKGIEDVQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TLVEKSKAFPSITFMAVNKAENWVSNIGESDVNAVTWGVFPAKEVNQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNDYINGDIFSVFA
>A0A4R5XHR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jeotgalibacillus sp. S-D1|TrEMBL
MKLAEALQEKILIADGAMGTLLYSYGTDQCFEELNLSQAEHIQQIHSAYIKAGADVIQTN
TYGGNYHKLERYGLQDQVKEINSAAVRNAKLAAEKDTHILGTIGGIRSIRPQSIALDEIK
RSFREQLYCLLLEGVDGLLLETYYDLEELSTVVEIARKATDVPIIAQVSLQEIGVLQDGT
PIAEALGRLEDLGADVVGINCRQGPFHMLRSLESVPLPKHAFLSSYPNASLPSYSDGDLQ
YNNNAEYFAECAKSFIAQGVRLLGGCCGTTPEHIRAFSGALQNAVPITEKKIIAPEPKIE
VRSKKIHVPEPLPSIVSARPSVVVELDPPKKLNTDAFMKGAQVLKDAGADAITLADNSLA
SPRVSNESLGHLIKQEIGARPLVHITCRDRNLIGLQSHLMGLHTLGLHDLLAVTGDPTKV
GDFPGATSVYDVSSFELIEMIQQLNKGVSMSGKDLGESTSFSIGAAFNPHVRSVERAVLR
MEKKIAAGADYFMSQPVFSNEKLLDVYEHTKHIQKPMYIGLMPLTSSRNAEFLHHEVPGI
KLSDEVRERMAKVSGDKEKSAQEGIAITKSLIDAALELFNGIYLITPFMRYEVTAELTRY
ANEQAAKRAGGIHHVSNIIH
>A0A6N7K066|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. MYb238|TrEMBL
MTALSFEFYPPKTDDQRAQLDRTASRLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLQAAPHLSCVGGTREEIRELLKLYRAIGVRRIVALRGDLPSGMGFPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLRHFKAKIDAGADAAITQYFYNADAYFHFVDA
TRRLGVDVPIIPGVMPISNFSQLRRFSEQCGAEIPRWIARRMQAYGDDTESVRAFGADVV
AALCERLIAGGAPSLHFYTLNLAKPTSAVLQRIGRG
>A0A2M8QQS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. LB126|TrEMBL
MTLSFPSVEEASQAWQAPLYADLAGDVNVSFEFFPPKTEKMEEQLWSAIQTLTPLAPKFV
SVTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKAEIDEVVDAYWEAGVRHIVA
LRGDPPEAGSKFEPHPEGYKGAAELVEGLVKRHPFEISVAAYPETHPDALSAQSDIDNLK
RKLDAGASRAITQFFFEPDTFFRFRDTVAAAGIDAEIIPGIMPVSNFAAVQRMSAMCNTD
VPGWMGKLFEGLDDHAAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPATLEKTA
>A0A8I0W9U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus epidermidis|TrEMBL
MSRLLNHLKNNVLVADGAMGTILYSEGLDTCPEAYNLTHPNKVERIHRSYIEAGADVIQT
NTYGANFEKLKVFGLEHKVKEIHKAAVQIAKRAANKETFILGTVGGFRGIKQEDLSLSTI
QYHTDNQIDTLIEEGVDGLLFETYYDLDELTSVITATRQKYDIPIIAQLTASNTNYLVDG
TEINEALKHLIECGANVVGLNCHHGPHHMQRSFSHIELPEHAYLSCYPNASLLDIENSEF
KYSNNAKYFGDVAQELINEGVRLIGGCCGTTPEHISYIKESVKHLKPIKTKKVIPIHRTI
NTNAKRTLKQNLTSKVKQRPTVIVELDTPKHLDTELFFENIGKLDEANIDAVTLADNSLA
TVRVSNIAAASLIKQRYEIEPLVHITCRDRNLIGLQSHLLGLSLIGVSEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINVDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMSYFITQPVYSKEKIKEVYEATKHLDTPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYLITPFQRIDYSLELAAY
SKAITQNKEAIS
>L0M8M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium (strain FGI 57)|TrEMBL
MSFFHANQREALNQSLAEVQGHINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPHWMSTMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7R7C4D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L-8-3|TrEMBL
MIEKRPPQRDENPEGIHLPLEPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RARIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVGNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNGKFLSGRKLTTPPQ
LFLGAAINPFAPPYDFRPYRLGKKIAAGAQFVQSQYCFDVPMFREYMKRVRDLGYAEKCF
ILVGVGPLASARTARWIRSNVPGIHIPDAVVERLEGAQDQKKEGKKLAIDIINEVKEIQG
VSGIHVMAYRQEEYVAEIVDESGVLKGRRPWKREPRSDDHVVAQRLDHILHDNVTESQID
MVKTAH
>A0A534KT85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MRSGSRLERILASGAFAVTAEIAPPASADGTEIRKNASRYRGTVDACNVTDCTRARVHIS
SLAAAAIAIQEGVEPVMQMVLRDRNRIALQADLLGAAALGVRNVLCLWGDPPSAGNEPEA
KGVFDMRTEDMIEMFRNLRDAGTLRGGDAVETPPKVFIGAAADPFRGSKEESFGKLRAKV
MAGADFVQTQGVYDVDAFEEWMRLVRKEWLHEKVYILAGVIPLKSAKMARFMVEKLGAVV
PKHIMDRMENAPNAKAEGLSIAVRTIKALKKIDGVRGVHLMPVGWDGVVPKLVKDAGLAP
RPETAV
>A0A0R1W7Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limosilactobacillus oris DSM 4864|TrEMBL
MTSLSYEVFPPNSTVGINHLNQVLAALQDLAPSFISVTCSSQTASLAQETVRVADYVENC
CHVPAMAHLPAWYLSRSDVDRIMAQLRERHVGRVLVLRGDERPGLAKKNDFPHASDLIDY
IRQNYPDFQITGACYPEKHPESLDMVAELQHLKLKVEAGCDQIITQLFLDNRCYYRFREL
CAIAGIDVPIIAGIMPIINEQQANRILRTSAVAVPEKFKDILAKYHDHPEALKQAGISYA
IDQIVDLATNDVSGIHLYTMNQADTARQVEQNIGALLQVSC
>A0A193BW67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis orientalis|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPEGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTLRTLHTTIKLSGAPAPRRLLDRLEPLA
DDPKAFRAAGIDTVTELCERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A2K1PEP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrotoga miotherma DSM 10691|TrEMBL
MKIVDLIKQSNKPVLSFEIIPPNVGESIDSIFNVVDNLIEFYPKFINVTKHANEIEYVEE
NGKIMKIIQKKRPGTVGVSASIKHRYNIEVVPHLICTGFNKYQLEDILIDLNYLRIENIF
VVRGDKKRYTWKETDEYEHASQLVEQIANMNRGIYTFPTKEHNSTNFCVGVAGYPEKHFE
SPNFEKDLDYLKLKVDMGATFIITQMFFDIEYYKNFVNKVRDLGIEVPIIAGIKPLGSKK
TLYNIPKTFHVNIPKSIVEEFEDAKSSQDEYIIGVRHAIKLIEQLLELGVPGVHLFTMGK
GKIVKDVLSAFKGIF
>A0A3R9IM32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus cristatus|TrEMBL
MVNRQTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLAE
FISNDLEIPTIAHLPAVYLTKEMVSNILQALDRVGVNQILALRGDIFPDVAPKDDFRYAT
DLIEYIKTAAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRT
AGLAYAVDQIVDLVTHDVAGIHLYTMNNAATAYHIYKATHALFNHTPSVQSF
>R6IXA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:217|TrEMBL
MKIKAILEQKPTVSFEVFPPKQWDKIEGTKAVVKEMVKSHPAFMSVTYGAAGTTSGFTTE
IAREILDDGVTPLAHLTCLTSTRDKIHQVVAELQENCIENILALRGDIPRDFQFPAEQYF
EHAYQLVNEIRTLGDFCIGGACYPEVHPESKNRVEDLEHLKQKVDCGVDFLTTQMFFDNT
VFYNFREMCAIKGIDVPLIAGIMPITKASQLERTVKLSGCSLPTKFVKIVERFGDRDDAM
QQAGIVYAAEQIIDLMANGVDHIHIYTMNKPDVAGAIVRELGSIIHE
>A0A3C1PCI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktothrix sp. UBA8402|TrEMBL
MNRFRTACQTLDEFIITAEVAPPKGADPSHMIEMVRLLKNRVHAVNITDGSRAVLAMSSL
ASSIILLHHGVEPIYQVACRDRNRIGLQADLLGAQALGIRNVLALTGDPVKAGDHPDAKA
VFDLESVRLLQAINKLNQGKDWNNKALPDGATDLFPGAAVDPQSSSWSGLKSRFERKIEA
GAQFFQSQLITDFERLDKFMTEIAGESKKPILAGIFLLKSAKNARFINKYVPGVCIPDAI
INRLEKAKNPLEEGILIASEQVKTAHQLCHGVHIMAVKREDLIPEILDLAEIKPFL
>A0A4S4AJF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium composti|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKTDEMEARLWETVTRLEPLKPNFVSVTYGAGGSTR
ERTARTVKRILDQSALPPAAHLTCIDADKDSVDQVIRQFVDLGVTRFVALRGDPAAGVGT
RYQPHPGGYANGADMVAALKRHGDFDISVSAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDIYERYVERVRRAGIYIPIVPGILPVHNIRQVANFSARAGAHVPPWLSERFE
GLDDDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLAFAICHMIGIRSQPSERG
IGAAAGSAAA
>A0A7V6DQE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans|TrEMBL
MTMTAGSNLEKILKAGHKAVTCECGPPRGADAEHFRHKASFLKGYADAVNVTDNQTAVVR
FCSLAACRILLDMGIEPVMQMVTRDMNRIALQSNVLGAAALGIKNLLCLTGDHQSFGDHP
QSKNVFDLDSVQLLNTVRMMRDEGKMISGTEVQGRPAMFIGAAANPFADPFEFRVVRLAK
KINAGAQFIQTQCIYDMERFGKFMEMANDMGLTERAYILAGITPLKSLGMARYMQKFVPG
LLVPEEYITRLKGVPKDKQAEEGIKIAVEQIQQCLEMKGIAGIHLMAIEWEERAPEILKA
AGLHPRPKVD
>A0A765XAW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSCLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A844IEG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanizomenon sp. UHCC 0183|TrEMBL
MPDTYSFSAFNNFRTAAQRGDFLITAEVAPPKGGDPIHTIEMAATLKGRVHAVNITDGSR
AVMRMSSLVASVILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPQAKAVFDLEAVRLLQLIRNMNQGFDFNEKPLTDGALDLFAGAAVDPQSKSWSGLQS
RFEKKIAAGAQFFQSQLITDFEILEKFMNKIACGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPEHIVERLAKAKHPLEEGMKIAAEQVQTARGLCQGVHIMAVKREDLIAPILDLAGV
EKVN
>A0A6H1C750|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. DMU1|TrEMBL
MDRLRAPRGARIPFSVEFSPPRDADAEARLWRAVREFERLGPAFVSMTYGAGGSTRDRTV
RVTGQLAQETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWTR
HPEGLEYAEELVRLVRDLGDFHVGVASFPEGHHRSPDLEHDTRYLVHKLRAGAEYSITQM
FFDVEDYLRLRDRVVAYDPEQGAKPIIPEIMPITSLRTARRSLELSGSRLPAALEERLVR
AAGNGPEEDRAAVREVGIDVATEMAERLIAEGAPCLHFITLNFARATREVLARLGIAVPT
AV
>A0A7T7C1M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia sp. cqz5-12|TrEMBL
MSASEHPSGISFEFFPPNTEAGREKLKGVRDQLAALEPEFFSVTYGAGGSTRERTFNTVQ
SVSASGICTAPHLSCVGSDRGELREILAQYREQGVKRMVALRGDLPSGMGSRSELRYANE
LVEFVREETGDHFEIAVAAYPECHPQADNYHSDLANFARKMQAGADIAITQYFFTADAYF
HFVERARALGIEQPIIPGIMPITNYTRLARFSDSCGADIPRWLRRQLESYGDDSDSLQAF
GTEVISRMSQRLLDGGAPGLHFYTLNQAEPCLKVLENLGIASR
>A0A260UWZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 14-2483-1-2|TrEMBL
MNSESHSNGRASPGPTCSEHLSSGRPDGLRWGATYDLRVSEDSVRGRSSRGFVTRTPSIV
DRLRTEPEARIPFSVEFSPPRDEAAEARLWRAVREFEQLQPAFVSMTYGAGGSTRDRTVR
VTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRGITNILVLRGDPPGDPLGDWEKH
PDGVEYAEELVRLVRDLGDFHVGVASFPEGHHRAADLEQDTRCLVGKLRAGAEYSITQMF
FDVDDYLRLRDRVCAFDAEQGAKPIIPEIMPITSLRSVRRMLELSGTTLPSHLDEKFTRA
AGSGPEEDRAAVREVGIELATNIGERLISEGAPGLHFITLNFARATREVLSNLGLAAARV
>A0A0R0D3J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas ginsengisoli|TrEMBL
MTALSFEFYPPKTDDQRAQLDRAVRKLKGFAPTHASCTFGAGGSTLSYTSETVRRLRQDH
GLDAAPHLSCVGGTREEIRELLKLYRALGCTRIVTLRGDLPSGMGHAGDLRHAIELVEFI
RAEHDDHFRIEVAAYPETHPQASCALADLRHFRDKVAAGADAAITQYFYNADAYFHFVDQ
VRALGVQVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIARRMAAYGDDAESIRSFGADVV
AALCQRLIEAGVPGMHFYTLNLAKPTSAVLSRINPSAG
>A0A2G2C4R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moritella sp|TrEMBL
MKYSIELVPRSWETLNTEAEEVSQFSQINTLNIPDLLRFDVRSWDACDRLQDKFDEVIPH
LRAIDFDLRNGFPLTDFFRHSKINSVLVVEGDPPQDISHRTYRNTSCELIRIIKKELPYM
KVYAAIDQYRTSMRKELDYIHDKLDAGVDGFFTQPFFDLKFLDVYMDMLQGTEVFWGLSP
IHSETSKSYWENKNDVVFPSDFEPTKEWNIKFGRAMIKKVQAKDDNVYFMPIRANASEYL
DKLLAED
>A0A521DJZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus aquaeductus|TrEMBL
MQGRARSPHVPSVPVTPSVRELLASSRPTWSFEFFPAKTPEGDAQLWTALRQLERLQPSF
VSVTYGAGGSTREGTVAVTERIAAETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLL
ALRGDPPGADPQADWVKHPEGLEYASELVELIRSMGEFSVGVAAFPERHPRSPDLDTDVE
MFVRKCRAGADFAITQMFFRVEDYLRLRDRVAARGCDVPLIAGVMPVTNARQIARIVQLS
GQAFPEELAARFAELDGDAPEDKVAVRAYGVEVATAMCRRLQDEGVPGIHFITMNRSTAT
REVFTNLTDAGTGVSVPSTLAGAPGAR
>A0A6D0EP91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKEQTGLEAAPHLTCIDATREELSAIARDYWNNGIRHIVALRGD
LPPGSGKPEMYATDLVALLK
>A0A2G2IKB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moritella sp|TrEMBL
MSFHNAQNIEVLNQSVSELGRDINVSFEFFPPNSPAMTSTLWESINRLKALNPKFVSVTY
GANSGTRDRTHDIIKQIKHETGLIAAPHLTCIDANRQELKQIATDYWDNGIRNIVALRGD
LPPGLNQPDMYAADLVALLKEVNDFDISVAAYPEVHPEAKNAQADLLALKDKIDAGADRA
ISQFFFDTESFLRFRDRCAAVGIDKEIVPGILPVSNYKTLCKFSKLTNVKVPNWMHSQFE
GLDNDQATRNLVGASIAIDQVKILSREGVKDFHFYTLNRADLTYAICHTLGVRPR
>A0A444REP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSY
>A0A7J7QGG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scenedesmus sp. NREL 46B-D3|TrEMBL
MKIVDKINANIQEGKTFFSFEYFPPRTEEGVENLFERLDRMVAYGPTFCDITWGAGGSTA
DVTLGIATKMQNLFCVETMMHLTCTNMPVEALDNALTEVRKAGLQNILALRGDPPKGQEE
EKHGDYFGIGVAGYPEAHPDFIVDDPEQMKKNYWDSLAYLKRRIDAGGDFIITQLFYRVE
RFLQFVEDCRSIGITCPILPGVMPIMTYGGFKRMTTFCKTDVPQAITDALEAIKDNDEAV
KAYGIQQGAEMCKQLLDAGVPGLHMYTLNLERSAVGILETVGVLDTSKVPRSLPWRQVPS
TRPGESVRPIFWSNRPKAYLHRTLDWDSFPSGRWGNSRSPAYGTLSDYQFMRRHTSSDKR
KGAARAAWGAELAGPEDVADVFVRYCKGEITMLPWAELEGLHSETSLIKEQLLALNAAGY
LTINSQPALNGLPSSDAQFGWGGPGGYVYQKAYVELFCAPEKLQPLLDKLDTAPAITYIA
VNAQGDVRSNMKEDSVNAVTWGVFPGREIEQPTVVDLVSFMVWKDEAFELWGSEWGTLYA
EGSTSRQVLADIAGSWWLVSVVDNDHVKGNLLRCLDCDQQQNAVCTHGVASGACWQLVFD
QTFSVMDVCYSPLKMLGREFYPRGPCVYVVAVSKNKNAQD
>A0A855XEH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limosilactobacillus reuteri|TrEMBL
MTTLSYEIFPPKSQVGKDNLIRTIAELKKLDPKFISVTCSNKETNFIQKTIGVTDYVQNQ
CDISAMVHLPAWYLNKKDVDQILYDLCKRHINQVLVLRGDTRKNLKKKGYFEHASDLISY
IRQNYPDFHITGACYPEKHPESLNMVEEIQHLKFKVNSGCDQIITQFFLDNHHYYHFREL
CAIAKINIPIIAGIMPVTNTRQITRILKTSTVKIPEKFKKIWTKYHDNPSVLNEIGITYA
IDQIVDLVTNDVDKIHLYTMNRFKTAHKIKSNIGSLLK
>A0A7C4KZ63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanomethylicus sp|TrEMBL
MKIFSNFMKELYNGNFVFTSEIEPKKSVKIDYLIDKANFLKKYVIACNVTDNPRANAYLN
SIVASYIIQSHTGLETICHMTVRDRNRIALISDVLGASILGIKNVLVITGDHTTMGDNPN
AMPVYDIDSTQFIKMLRRMIDEGVDINGNPIDGEIKIHIGAVGNPNANPIEVELYKVERK
IKVGAEFIQTQITFDIEKIKNFIDYLKPSPPFILVGIFPCKSYRIAENVEKKLPGIKIPE
EYKNKLKKVEGNSEKIDEVNIEYFSNLIKEIKRNTKASGVHIMTIEYERIIGKIINSL
>A0A6P2C1L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trebonia kvetii|TrEMBL
MAGGIKFSHVKPYHEVTRTVSDCGNGHHVSTVLNDFSMEMTGKDVEKVENAAGVIPRGTR
INVTFLENEDLTMRVNAAAAVKRLGFTPVPHISARRLKSQEMLEEFLTALRAIDATESVF
SVGGDPAVPMGPYEDSLAVIESGVLQQYGVTDISVGGYPDGHPDIASEVLWSALEKKSAA
LSRLQIPGTVITQVDFDVDRVLSWVAEVREHGVEMPIRVGVPGPASVKLLLGFASRLGIS
TSATIAKKYGLSVTNLLGKAGPDRFIRDLAAGLDPGKHGTVKLHFYTFGGFKTTAEWISN
FSL
>A0A2M6YW85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriales bacterium CG07_land_8_20_14_0_80_59_12|TrEMBL
MKKPFRERLLDGPIVCDGAIGTLLDMRGFREMPHEAEILRRPEVIEEIHREYREAGAEII
EANTFGANAIRLSEYHLEDRVRVINLAAVAAAQRAAGDDAYVAGAVGPTGRLLEPIGSLK
LSEARAAFHEQIEALVEARVDLLMLETFVNLDELDEAITAAKELTDLPIVAQRAFPEDGA
LLATRFPSEVLERIRDRGVDVVGSNCTVGPQRMFSIMKSMHSSGVILSAQPAAGIPMLVE
GRAVYHATPEYLATYARELLKTGVTLIGACCGSTPDHIRAISKVVREFRDGAPSTVERVS
VRTAAEPEAEEGKMQSVSRSAFARNIGRKFLTSVELDVPRGFDISSVFEGAAYLKDQGID
AINITDGARARLRMSPVAISHLLQRRVGIEAMTHMTCRDRNLLGLQADLLAAHALGVLNL
LAITGDPANIGDYPQATSVFDVDSIGLIRAASAMNRGQDIMGNSLGGRASFLIACAVNPL
ADDLEREMDRLARKVEAGAEVAYTQPVYEVETLQKLILKAEPLHLPIMVGVLPLRGYRHA
EFLHNEVPGLVIPEKIRERLRKGGERTAAVGVEIAGEFLREARTMVQGVYLMPPFRKNQL
VIDILGFL
>A0A379L5Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVQVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRTETGDHFHLEVAAYPEMHPQARNFEADLGNFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLALWNNLKLPR
>A0A6H5KKX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectocarpus sp. CCAP 1310/34|TrEMBL
MKIIDKIQQAMEAKEPFYSFEFFPPKTSAGVENLSARMERMATLEPLFVDVTWGAGGSTS
DLTLAISANAQKYLGVEVLMHLTCTNLKVEEIKGALNKAREAGIQNILALRGDPAKGLGN
WEAAEGGLRHAIDLVRLIRQEHGDYFGVAVAGHPEGHVDGRTGAEEGEEDDDRRGEGWEA
LELKRLKEKVDAGADFVITQFFYDTEAFLSYVERCREVGITCPIIPGIMAIQNYNAFTRM
TDFCETRVPSEVREALKPIMSDDDAVKDYGVDLGIRMCKALTEAGAPGLHFYTLNLERSV
RLILDGLGYTETAATRRMYPWRASALSKRAAEDVRPINWANRPRSYLARTEVWDEYPNGR
WGDGRSPAFGELSDTHFFRPLVGTREDRKAMWGEAPIVPGEIFETFASYIEGKIPKLPWC
EVSLQQESSTIGKELAAINRRGFLTINSQPAVNGAPSDHPVFGWGGGGGRVYQKAYVEFF
TSEALLDEVLEACASRPELNYYAVDVKGRTRSRGVKGTTALSWGVFPNREVQQPTVFDPE
TYMVWKGEAFRLWVDLWASLYDEESKSAELLHDIHDSYYLVAVVDNNFIDGNLWEIFSQG
T
>A0A0F2QZ35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatitalea sp. BRH_c12|TrEMBL
MLRVFQNDLVDPDHFTITLELVPGREAMGLGVDTVMGIARDAFADGRVSAVSITDNPGGN
PSLSPDVLGHQIFQIGMDVIVHFTCRDMNRVGMESRALQLAMMGMKNILALNGDYSGKGF
GGQGAPVFDIDSVQLQILLGLLSERIQASGDPDVFFGGCAVSPFKQTEGECFAQYAKLCR
KVAAGAQFIITQLGYDARKFQELIQIKNYMQLETPTLGSVYVLTPRAAEIMHGGKVPGAV
VTDALLRRIKKESRDPQAGRQAAIERTARLAAVLKGLGYDGIHIGGIHKNFDTAGRILDR
LAQIENRWREFVEDFDFPQPNGFYVFDRDSGSSPSTARFGRRPITPYLLERWRYAFLKLT
HDIFFNRDNWLAPLFRKTSQYLDGRVGSRVLIDLIEHPAKAILLQCAMCGDCGIQHVGFL
CPESQCPKHIRNGACGGSTGGHCEVYPDRPCIWYRAHRRLAHVGQTGQMVKGCVPPRMWE
LNHTSSWLNFHLGRDHQSVSSQITLRCRASSCTF
>A0A2M8NK90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phototrophicales bacterium|TrEMBL
MVSTSRLERKLRAGDFAIVAEVYPPTSADLTAWLDHVEALRPYADTLQLTDMPLATPHTA
NLAAGALLVGRGFDVMINITCRDRNSIAQQGYLLGAAAVGIHNIFCLTGDHPRFGDHPSA
APVFEMDSFGWLALAKQMRDSGILANGRAIESPPRVFLGAAAAPDSPPVESRPENALRKV
DSGADFLATQPILDVDAFRVYMARLRDLGVTERAFVIAGIMAITSMNQVDALRATPDIT
>A0A7G8WGZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nakamurella sp. PAMC28650|TrEMBL
MVTVRERLAAPGPHFSVEFFPPRDDAEESTLWLAIRRLEPLRPAFVSVTYGAGGSRRDRT
IRITERIAAETTLLPVAHLTAVGHSVAELRHVIGSYASVGVRNILALRGDPPGEDPSAEW
IAHPQGLHHASDLVALTRSLGDFHVGVAAFPDMHPRSADLASDTRYFAEKVAAGADYAIT
QMLFSAQDYVGLRERSLQAGADIPILPGIMPVTSYTRLMRIIELSGQRVPEDLAGQLHGV
QGDAAAGREIGMRHAIAMCEQLLAEGAPGLHFYTFNRSKATLEVLTALGMTRSSGPTGRI
PALQT
>M5IRM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter showae CSUNSWCD|TrEMBL
MLKEKILNKEKGLVLYGLTPPKAEFDEAKLRDISDRWTGRIESINADGLVLYEVQDESER
NDSERTFEFSGTLSPEIYYRDYLNVATPSVFYRVASGYDEDAFRAAIAAQSSNLNVLVGA
TSSSQKVRLNLARAYEIAGEFENLAVGGVCIAERHAKKGDEPQRMREKIAAGAKFFISQA
IFDADMTRKFLEDCAAAKITEPIFLTFSTAGNPKTLEFIKWLGVSVPSAVDVRLNASEDY
LAQSCEIIKEIWRELKKFGDENGLNLSANIESVMAKRAEIEASLELAREFRQI
>A0A4R2Z012|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. JUb52|TrEMBL
MASPARQGGAAHERDAVKPSLSFEFFPCKTEAGHEKLIATARQLASHGPEFFSCTYGAGG
STRDGTYRTVRQLNDEVGVPTAPHLSCVGDSKAKLRELLQQYREAGINRIVALRGDLPSG
MGLSGGGELRYASDLVAFIREETGDHFHIEVAAYPETHPQARSFTDDVRNFVYKMQAGAD
RAVTQYFFNADCYFHFVERVRKLGVEAPVIPGIMPITNYSKLARFSDACGAELPRWLRKQ
LEAYGDDTQSIQAFGEEVMTALCERLLEGGAPGVHFYTLNQAEPCIAIWRNLGF
>A0A076PD75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas testosteroni TK102|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPEFCSVTYGAGGSTQAGTFTMVRDIQNE
GVGAASHFSCIGATHEKVRAELNELKAMGVKRIVALRGDLPSGYGLGGEFQYASDLVAFV
RQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VRALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A524BUN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRSLLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITHMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>K0NMZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula toluolica (strain DSM 7467 / Tol2)|TrEMBL
MKIYSQLHEKLSRGEFAITGECGPPRGANKEVIDKKIKLLKGFVDAVNVTDNQTAIVRMS
SIAASAHLVAAGLEPVMQMVVRDRNRIAIQSDIMGAYSLGIKNILCLSGDHQKFGSQPEA
RNVFDIDSVNLIRTVRNMRDTGKDMSGFDLDVAPQMFIGAAANPFADPFEYRVIRLGKKF
DAGADFVQTQCIYNMGRFKEWIRLANEEGLTQKGYILGGVTPLRSAGMARYMNKKVAGMD
VPEEIIKRMDGVEKKCQADEGIKICLETIQALKELTGVHGVHIMAIEWEDAVARIVEQAG
LN
>A0A349DQS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microscillaceae bacterium|TrEMBL
MTKIIEYIKNSEKTLFSFEIIPPLKGQSIQSLFSAIEPLMEFKPKFIDVTYHREEYVYRD
RGQGLLEKNVTRKRPGTVGICAAIMHHFQVDAVPHLICGGFNKEETENALIDLNFLGIDN
VLVLRGDAIKSEGRFHADPNGHKYASELLDQVVKMNNGVYMDEELKNPYPSNFCIGVAGY
PEKHFEAPNFTTDMKYLKMKVDMGAEYIVTQMFFDNQKYFDFVKQCRDSGIDVPIIPGLK
PLTSSKQLTILPSIFHIDLPQDLVDAVTKCKSNDEVRQVGIEWGIQQSKELIDFGVPVLH
YYSMSRSKAVKEIASALF
>A0A5X5NNI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Colindale|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A257G5U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. PASSN1|TrEMBL
MATPLIHPNWDKPPLGITDGFSLEMTAKDEASLRDAAHLIPADTPIAVTFLPGEDVAARV
KATVAVRELGFEPMPHFSARRITSEDDFEGYLKAVVGQAGVSRAFIVAGDPPEPVGPYFD
TSALIATGAFERSGIKAIGIGGHPDGHPNMTEQQCWDVLVKKVTEIEARGMAPLIVTQFG
FDPDAFLAWLLKLRALGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVTN
LLGSAGPDKLVDAFAKGLGPQHGRVRLHFYPFGGMVKTLEWVHAYNAKHGL
>A0A1H4RYP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides exalbidus|TrEMBL
MRNKQSAATLTRLLEHARYEVLPTATTEDKVLEHLPRDRTITVTASPAKGLDATFDLAER
LAGHGYTAVPHIAARMVTGRTELSEIVDRLTGKGITSVFVPGGDAEAAGDYPDALALLED
LKDLGSPFSHVGITGYPESHPTIHDDLTVQSMWDKRRYATHIVSNLTFDPAVVKDWVRRL
RTRGVAMPLLLGIPGPVERTKLLGMATKIGVGESTKFLAKNKGLFARLAAPGGFTGESFL
EKCAPALGEDGALVEGLHVFTFNQIGETEAWRTDMLERLRNG
>A0A1H2ED34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula phenolica|TrEMBL
MTLQNKLSQGDFVVLAEINTPKGVDISDLVTNVRHLKSRIDAVVIPGMDNGVMHMSALAG
GAIIRQQGMEPMIHIYGRDRNRMALQGDMLAAHILGVNNLLVVQGEAISHGDHQNAKPVD
DLNELDLLIMLNTLQRGTDLAGFELKGKPEFFTGCQVQPIRNDDHLEIEFQSAGEKVEAG
AQYIMVPPVFDIDGYVQILNKFKSLNVPVIATVYMLKNVGMARYISINDPASKLSEATIT
RIRKSKDRETECINIAGEMIKELQSQVQGVKISASGWEDRLPAILDCAGL
>A0A1H4ZRJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides exalbidus|TrEMBL
MTHSRDVDRDLSMRELLAQGGRSFSFEFFPPKDEAGEEQLWQAITELEPYGPTFVSVTYG
AGGTTRDRTVAITARIARETDLLPVAHLTCVGHTTHELDAILDDISEAGVRHVMALRGDP
PGGPGSPWTPTEGGLTYADELVALVRERHGLRVGVAAFPEGHVDAVDLEQDAKVLKSKQD
AGAEFAVTDMVLRASDYVGLVERARAVGADLPIIPGIMPILNLRSMERMVEFSRRELPEE
TVARLQPLADDPGALRAEGIAIATEQCEQLLDAGAPGLHFYTLNRSKATREIFANLSITV
>A0A2W4XTU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phormidesmis priestleyi|TrEMBL
MNTAPSGQSPSGLSNGTLSNGLANGLTQRSPGRLRQAIQAKEFIVTAEVMPPKGGDPSHM
LAMAAHLQNWVHAVNVTDGSRAVLRMSSLACSVLLKQAGIEPICQMTGRDRNAIALQADL
MGAHALGIRNVLALTGDPLKAGDHPKSKPVHELESIRLLQVIRQLNSGTDYNDSAMTDGC
LDIFPGAAIDPQSPSWSGLQSRFEKKLAAGAQFFQSQLISDFDKLEKFMDNLAVGCDRPI
LAGIFLLKSAKNAAFINRCVPGVTIPQHIIERLDKAPDPLQEGIKIAAEQVQSARDLCQG
VHMMAVRREDLIPQILELAGVAPQTEPKTKPKTEVLSAVG
>A0A1J0VPV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia mangyaensis|TrEMBL
MDFDNGRGRSTPDRPASARQIVSRTPSVVQSLRTHSGSGVPFSVEFNPPRDAAGEARLWR
AVRQFERMHPAFVSMTYGAGGSTSDRTVRITGELATETTLLPVAHLTAVGHSIAELRSLV
GSYADSGIRNLLVLRGDPPGDPLGEWHKHPSGVEYAEELVRIVRDLGDFHVGVASFPQGH
HRSPDLDHDTLHLAAKLRAGAEYSITQMFFDVEHYLRLRDRVVAMDPIEGAKPIIPELMP
ITSLRTVQRAEELCGRTLPKSVMTRLEKAAGTAPEEDRAAVRAEGIQIATEMAQRLIDEG
APCLHFITLNFAKATSEVLTNLGYGVTAAPISA
>A0A851GYJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sediminibacterium sp. Gen4|TrEMBL
MKITEHIEQAKDTLISFEVLPPLKGKTIVSLYDHLDPLMEFKPSWINVTYHRSETMFKKK
GDGTFEKVEVRKRPGTVGICAAIMNHYQVDAVPHIICGGFTKRETEDALIDLDFLGIDNV
LALRGDAAKNEASFEPEPEGNHYAIDLLQQINNMNNGIYLDDDIKNGGKTKFCIGVAGYP
EKHFEAPNLDIDLQKLKQKVDAGAEYIMTQMFFDNQKFIEFVKSCKAIGINVPIIPGLKP
LTNKKQLSVLPRIFHVDIPSDLSNAIMKCKTDVECEQVGTEWLIQQSKELKEFGVPVLHY
YTLGKPKVIWNVVKELV
>A0A717U947|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Typhi str. CT18|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFYFYTLNRAEMSYAICHTLGVRPGL
>A0A1I0CDN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronincola peptidivorans|TrEMBL
MLKEKILRRESGIITYGLTPPKQRNTLEKIQEISQKQIERIQNLEIDGLVIYDIQEEADR
IKDERPFPFLPTLDPGLYSNKYLEELNIPKIIYRCVSKYTQEELSEWMKVDTAQDKFSVF
VGAASRKQKVNLSLQQAYHLRNEVNPDLLLGAVTIPERHIIKHDEHMRVIKKMENGCKYF
ISQAVYNVEASKNFLSDYYYYCMKNQIEMVPIIFTITPCGSIKTLEFMRWLGISIPRWLE
NDLKSTENILEKSVDLSKEMYKELLDFALEKGIPFGCNIESLSVRKVEIEASIELVEAVQ
QINKRMLYQQVQA
>A0A2N0MBN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G9|TrEMBL
MKVTDRSYQATGQPCFICDFSPPRTGDVGLVDQANIDADFISVAYNPGRAVRVNSAMLAA
AIKQRNGKDVTFTLATRDMNQLALQSQLLGAQMLGLENLVLVQGDPFSPRDLTRTKAVDD
ISPTGMIAAVKSMNQGLDFRDSQLRMPTDFCIGATADLGRGLGPEAMLTHRKVMAGADFL
VTQPIFDLAEAEGFAEAYRATAGETLNLPVFYGLQILEQDGVIFSSVPQAVRDQLEGGRP
GVEIALELYQSFRANGLQNIYLVPPIRRGGARSYGAAREFLAQAKGA
>A0A3P1W8P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchananella hordeovulneris|TrEMBL
MSTKLLFTGPRPRPLVSFEFFPPRRSGNLSLTWAGIDKLLAAAPDFVTVTYGAGGSTRSQ
SVDVWRHIRHSTSVPAVAHLTCIGATRGQVADTVRGLLQLGVRSFLALRGDLPQGDTPAT
YTPRVDELNRAVQLVELIRDTAAACLPDPREVSIAVAAYPGPDSPRFANDLAALRDKVAA
GADYAITQVFLEASHYARLREHAAAVGVQVPLLPGFVPLTDARRVQRVAELADIEVPTHL
AAALCIANPRDRLRAGLRATLDLIGQTLAAGAPGVHLYTFNRPRPSLDILEYLHATRFLS
CPADRDVVEDLVEATLDTLTPVG
>A0A374UAH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. TF06-6AC|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A1F0R259|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC066G07|TrEMBL
MTTVHPALSFELFPPRSHASCESLLHTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHDLERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSNAE
LHRIGVEYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEF
A
>A0A5M6CXD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseiconus nitratireducens|TrEMBL
MTLPTKLADYFKGGRCAMSFELFPPKTDEGMALLEKNVERLQAFHPNFFTCTYGAGGSTQ
SRTLDVVEKVKAITGLPVASHLTCVGSTVDQLRDYLKEAKRRGADHIVALRGDPPKGSET
FQAVEGGLRYANELVELIRADFGQHFGIAVAGYPEVHQEAPDPQTDLDNLKRKVDAGADV
VVTQLFYENSDFYRFRDDCVKAGINVPIVPGILPVTNYKQACRIAAMCKARIPDEMAAAM
NESDDADFQFNVGVDHARRQTIDLIENDVPGIHYYVLNKSSAAAQMLDGLSLGADA
>A0A1D2VNE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ascoidea rubescens DSM 1968|TrEMBL
MSLIVDKINNLNLDDSFISLEFFPPKTEAGLKNLLARIERLSVLNPLFVNITWGAGGSTA
EKSLELAAYCQKVLKLTTCLHLTCTNTNKRIIDDALLKAKKAGIRNILALRGDPPRSDEH
LYKEDSEKYEFNYAIDLIKYIKEKYEDYFCIGVAAYPEGHVDGSYASDQDYHKDIPYLVD
KIKAGGDFIITQLFYDYNKYLEWEKEIIKIEEIKGIPIIPALMPINSFSSFNRASKLSHA
SIPKFYLNRFSKDIINDDNQVKKIGNEILIDIINNLYNSFSGNKIKSRGIHFYTLNLEKS
IAKIVTNCRYLTSSFIINFEDEDEEFISNNNNNIIDDNNNTADNSNVLKFRKHHENLINN
RKEIANDPRKSIFSYRLTPKTILEISAGSGTLGKEATWDEFPNGRFGDSRSPAYGEIDGY
GPSIKIPIGIKNPLIELWGFPQNIQELSKIFINYLLKKIKYLPFSDLEINPETLLIQEFL
IEINSKGWLSIASQPSINGCNSYDKIIGWGPRNGFVYQKSFIEILVSKDDWENVLKPKIT
TKEISQEELVGYYVTNHKGDFYETNLPEHNRSSAVTWGVFPNREIIQTTLLEEESFKVWK
DELYKILLEWSNLYLVSGKNSKSDQDKTRAMNSFKLIRSMYDSYYLVQIFHNDFSEENAL
WDLLLE
>A0A4Q0SPX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium zhanjiangense|TrEMBL
MTDVTTPGQDNRQDGHLKRPAISFEFFPPKTEEMERNLWDAINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPVG
GIGTPYFSHPDGYQSSAELVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A2A4I9K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas adhaesiva|TrEMBL
MTISVNQLEEARRALDAPLYADVGGDVEVSFEFSPPKTDKAEENLWQSIETLCPLGPRFL
SVTYGAGGSTRDRTHATVARIARETSVPAAAHLTCVEATREEIDAVASEYWAAGVRHIVA
LRGDPPAGAADYIPHPGGYENAAALVAGLRRLHPFEISVAAYPEMHPNSPDQAADLDNLK
RKLDAGANRAITQFFFEAETFFRYRDAAAAAGIDAEIVPGIMPIGSFAGVQRMAAMCNTA
VPGWLVRLFEGLDDHPGARQLVAATVAAELCRKLYAGGVEQLHFYTMNKAELSFAICHLL
GVRAAPVQATAAAA
>A0A315FLF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans parvus II-B4|TrEMBL
MSGSKLPISLEFFPPKTPDGAEKLRVVRQQLYGLKPEFCSVTYGAGGSTQEGTFATVGAI
LGEGVAAASHFSCIGATKASVRAELATLKAMGVKRLVALRGDLPSGYGAGGEFQYASDLV
AFIRAETGDDFHIEVAAYPEIHPQAKSPESDLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGADVPIVPGIMPITSSTQLLRFSDACGAEIPRWIRLRLLGFGDDIASIKAFGL
DVVADLCEQLVNGGVPALHFYTMNQSAATTDILRRL
>A0A316WU06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium oncorhynchi|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINNLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELITEVENAKNNEAVKQIGIEWSIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A8I2EY93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MSLKDTFKNKTVFSLEVYPPKTPEGTKKLVNALTGIKRIKPDFISITLGAGGSQNNNALE
LSSLIQNDLNIPAMAHIPGIYRSKKDVADFLKQLKQHNINNVLALRGDINPDETPVGDFN
HASELAEFIKTQGDFDITGACYPQKHPESIDLVDDTLHLKKKVDNGVGHLITQMVFDNQA
FYDFRQRLKLAGINVPVEVGIMPCTNCNQIKHITELSGLEMPRKFVDIMNKYANNKEAMR
DAGIAYAVDQIVDLVANGVDGIHLYTMNNTYVAKKIWEATHSLFEATSYQPQHPSLSGSD
DQ
>A0A7S0J3I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calcidiscus leptoporus|TrEMBL
HVIVVDLLLRPPPHQRVPTRAVSMSTEGCVDTRGELPKITKGKINEMIASWTAQTSEPFI
SFEYFPPKTDDGVAKLHKTIAQMATQEPLFMDFTWGAGGATSTLTLALSTESQKQHDVMV
NMHLTCTNQDKELCDAGLNGAKAGGIKNIVALRGDPPKGQERWEVTEGGFACALDLVKYI
KANHGDFFSIQVAGYPEGHPDRITKVADLGRPMSAAEAARVVDVDGELHVCSDEDFVKEM
AYLKEKCDAGGDVIITQLFYDFDVFKTFVAECRKLGIKADILPGIMPLNAYGGFKRMTGF
CKTRIPPAMAAKIESLKGDDQKADFLEFGLQYITTLCQQLVASKLVSGLHFYALNQAERT
YQILKRLGYLQDPTKPRLPAKVDTRGEQLDVVLELLAHIEAKGGNAADMGRVLQAATAAK
GM
>A0A2S9Y275|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. M21|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0S8CXE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium SG8_35_2|TrEMBL
MQVQVLFEAGQLETLVDTYSSKLRRSLRDPEEFTLTFELVPGRGGRTQEISRIVSLAKDI
AVDGRFQALSITENAGGQPALSPETLGTEILAMGSEVIIHLSCKDKNRNQMESLLFGWDR
HNLHNLLVIAGDYPKEGYCGFPKPVFDLDTIHVLDMLSSMNQKGQVLQDKKAGTEQEKSI
PFLKGVVVSPFKMLESELVMQYYKLHRKVTAGADFVITQLGYDARKFHELLQYMKQNQLN
IPVLGNVFIPSLKVVELMHEGKLPGCLIPDFLYEQIQWEARTADKGKKARLVRAAKLLAV
LKGLGYDGAHIGGPALSFEDLDFILTLADEMASDWQRLIPDLSFCPPEAFHYYEKDRATG
LNSERATIRPAKKPPWMSAYSFSHWVHEAAFEPEGRLYDFCKKICLQLDETRLRGPLATF
ELISKAALFGCLNCGDCTLEKLAFLCPQSRCAKYLLNGPCGGSHKGWCEVYPGKKRCLYV
LAYDRLKPYGLEEKFKSGFIPPRDWSLNNTSSWVNFYRNLDNFAKSENPSGSCTQK
>E8WWG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulicella tundricola (strain ATCC BAA-1859 / DSM 23138 / MP5ACTX9)|TrEMBL
MTEVETKTELRGAAARLFTGGTVLCDGAMGSMLYGRGIFINRCYDELNLSQPDLVRAVHT
EYLQAGATVIETNTFGGNRIRLERHGLEEKVREINRAGVRLARECVQQMAEKHASEAFVA
GAMGPLGIRIGDGNKVTEEEAYAAFAVQVKALVEGGPGVGADLLILETLMAMNEARLAIQ
AAKAEGQGLPVIAMVTVDVNGNCLDGTSAEEAARLMTEWGADAVGCNCSDGPATVLAVIE
RMRTATKLPLAAMPNAGNPRVIDGRHIYLTSPEYMASFARKFIKAGATFVGGCCGTTPQH
TRAMRGALRAIGAQETGVEVVENGGAAEAGAARAQSKVMPPDLKDRSRVGAKIATGEFVT
LVEIVPPKGIDSSKELEGAEELHKLGVDAINVPDSPRASARMSAMSLCVQIQQRVGIETV
LHYTCRDRNLLSIQSDLLGASSIGLRNILCLTGDPPKMGTYPDATAVFDVDAIGLTKIVR
DMNYGLDIGGHSIGQSCGFTIAVAANPGVVDIDNEVRRFAAKVEAGGEYGITQPVFDLRL
LEQFLKRIEQFRIPMIAGIWPLTSVKNAEFMRDQLKVRMPEEILARMGAMPSPEHAKAEG
IAIAQEMLEESRAMVQGVQVSAPFGKYKAAAQVLGVL
>A0A0M9D7E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MRKQTFSVEIEANPGDLRQMKHYLHKWQPDFVSISNLSRYSYEEMVQCARYIQTDLHIPV
IIHLTGLTHTKEQIKKAFNELMDLNIRNFLLVRGNIHHNMHIEDDFNYASDLIKYVNQLD
TDSKINVFAGCYPDIHVLADSLTEDIEYLKEKVNSGVDSLISLMCFDNKRIYKFLDKSRE
YGINIPIRIGIMPITDSFKRHYLAHNDVKMPELFEKDDNLLENGIDYAVNQINDLYQHDV
NGIHLYTHNDWMVSDRVFESIKQNL
>A0A7V8QY03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. WYCCWR 11146|TrEMBL
MALKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTRAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRRQTKSAGAAA
>A0A365QJP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia reimsis|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLMPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLVDAGVPGLHFYTLNTAAATRTICERLDV
>A0A1H1PGS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gramella sp. MAR_2010_147|TrEMBL
MKVTEHIEKANGKTLFSFEIIPPKKGKNIQELYNNIDPLMDFKPPFIDVTTSREEHVYVD
RDGLFDRKITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFSKEETEYLLVDCHYLGIENV
MALRGDAMSHQRYFEPSNGGHPYACDLVKQITNLNKGKYLHDVIETDDLADFCIGVAGYP
EKHIEAPSLSSDLKRLKEKVDAGADYVVTQMFFDNSKYFEFVEEAKKAGITVPIIPGLKP
IAISKHLQMLPQVFKIDLPEALISEVEKCKNNKEVRQVGIEWCIKQSKELMEGGAPVLHY
YSMGKSSNIEQIGRAIF
>G0G654|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis mediterranei (strain S699)|TrEMBL
MTSVIERLRGDGPKFSIEFFPPRDTADEAVLWKAIRELEPYDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYASVGVRNILALRGDPPGDVYGDWI
PHPEGLQYAEELVQLVRSLGDFCVGVSAYTYGHPRSPDLETDTKYLVRKLRAGADFAIAQ
LFHGAEDFLRLRDRVAATGCDVPVLPGVMPLTTWRTLQTTIKLSGAPAPRKLLDRLEPLA
EDPKAFRAAGIDVTTELCEKLIAEGVPNLHFYTFNRSKATREVIARLGLVPARA
>A0A1G0XLB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_45_14|TrEMBL
MNLNYKRYRLEVSPPKQAVNHLSERLTRFDEKYNKAVDAGHCVCVTDNAMGNLAFQGHEL
IQELKLPVRFGQVMIHLNTFHTLSDLHWILDSCGELGIKEILVVSGDGSVRLPKLKPSEI
DCDSASVTSVELLGYIRKIYGSAFILGAAFNQYEPEAHEILKFRRKIEAGAEFIVTQPMV
GRNELIEKVMSKTKIPFIIEAWMSPNIKLLSDCIGYSIASEDTFDPMACLESLRNAYPAN
GFYLALLDFKTQFNNFQIKA
>A0A521DIB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharicrinis carchari|TrEMBL
MTAAELVLKDKETKFSFELLPPLKGNNIDRVFRSIDILKEFNPQFINITSHREEYAFETN
GQGYVEKKVIRKRPGTVAVAAAIQNKYGIKVIPHIISRGFTKTETEYALIDLNFMGIHDI
LVLRGDDTHKEKYPPRHEECNQYAIELAQQVNNLNKGIYLDGTSNEPFETPFAYGVAGYP
EKHEEAPNMDSDLLYLKAKVDAGAEYVMTQMFFDNQKYYDFVKRCRSIGIEVPIIPGIKP
ITTANQLNVLPKIFSCDIPEDFARELRKCKDNVEVKKVSVEWTIQQALDLKKNGVPIIHF
YTMMATESVRQVAEAVY
>A0A238K2U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Octadecabacter ascidiaceicola|TrEMBL
MSSPAISFEFFPPKSVQASFRLRDCVQTLAPLDPTFVSVTYGAGGTTRTLTHEAVDALVK
TSDLNVAAHLTCVDATRDETLTIARDYKAAGVNHIVALRGDPPKGASSFHPHPEGFDGAI
DLTRALANEGFEVTVGAYPETHPTATSQQACIDHLKTKIDAGATRAITQFFFEADIFLRF
RDACADAGITAPIIPGILPIENWTGVQKFATSCGANIPQVLQDAFAKATDPETFDLLATA
QATELCDDLLTQGVDHLHFYTLNKPELTRDICHALGVTPKQTLQNVA
>W0SJU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuritalea hydrogenivorans sk43H|TrEMBL
MTFELSIEFFPPQTAEGMEKLRATRARLAVLKPEFFSVTYGAGGSTRERTLATVMEIAAE
GHNAAPHLSCIGSTREGIREMLNTFIERGIRRIVALRGDLPSGMADAGEFRYANELVAFI
RGETGDRFHIEVAAYPEWHPQARSPREDLLNFKRKVDAGANSAITQYFYNTDAYEHFVAE
ARTLGVEVPIVPGIMPIASFSKLARFSDACGAEIPRWMRRKFESFGDDTDSVRAFGLDVV
TELCQRLIERGAPGLHFYSMNQAGLTLELCRRLDR
>A0A0Q3BHB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loktanella sp. 3ANDIMAR09|TrEMBL
MTRPAISFEFFPPKNIAGSFRLWDCVNALSPLAPEFVSVTYGAGGTTRQLTHEAVTAIDK
TTGLKVAAHLTCVDATRAETLAIANEYAEAGITDLVALRGDAPKGSDGFQPHPEGFASSI
ELIEALADTGKFTLRVGAYPEKHPEARSQADDIAFLKRKIDAGASAAITQFFFEADTFFR
FRDACMAAGITAPIIPGILPVENWKGASKFAAATGTSIPPVIAQAFENATRDGSADLLAT
ALATELCDALLQGGVEHLHFYTLNKPQLTQDVCRALGIAPQTRLQNVA
>A0A1A9HMV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mitsuaria sp. 7|TrEMBL
MTTPVSIEFFPPNTPVGTEKLKTVVQELRAVNPQYFSVTYGAGGSTREKTLSTVADIASS
GFDAAPHLSCVGSTRENIAEILATYRDQNIRRVVALRGDLPSGTATAGEFRYAAELVRFI
RETQGADWDIEVAAYPEYHPQQRYAARDLQFFADKVRAGASGAITQFFYNPDAYFHFVDA
TRAMGVEVPIVPGIMPINNFARIAQFAQRDGIEIPRWVALKMEGYMDDAASVRAFGLDVV
TRLCERLIAGGVPGLHFYSLNQSALTLALCERLGLAAKV
>A0A2X0ZBA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQAVGEFNHASDLV
SYIRSVKPDLKVFGACYPEGHYQADTIDQDIENLKIKVDAGATHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A5D4Y1E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lelliottia nimipressuralis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWDNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCITAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A257P5A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomonas sp. 20-64-9|TrEMBL
MKLSAEFFPPRTTEGLDKLVEVAEGFRPFNLDYLSVTYGAGGSTQERTLATVKALRARGW
DVAPHLTCVDSERGKIADLLKIYMYLGVHRIVALRGDIPSGMRD
>A0A840H6W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. CIR18|TrEMBL
MTDLTIPARADGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTPYASHPDGYQSSPELIAGIKKRHGDIEVSVSAYPEKHPEARDFDDDIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARAFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A7W1RB34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIDQILSTSAPVFSFEFFPPKTEAGEHNLYTALSELKTLEPSFVSVTYGAGGSTRGKTL
EIVKRIKDEYGLEAMAHFTCVGADVAELRATLDEMRDAGIDNVLALRGDPPAGEEVWSKT
EGGLEYSRELVELISADYPFAIGAACFPETHIHAASPEEDLEHLAEKVSAGVDFLITQLF
FDNALYFDFVERARAAGVNVPIIPGVMPITKVGQVERMAKMCGSEISEPLHHELHARGED
PEAVLDFGVAYATLQCAELLAAGAPGIHFYTLNRSPATRAILSALKLAKPWEKAVYPGSI
SRPSATRGEPSAAS
>A0A7D7RD28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Conchiformibius steedae|TrEMBL
MKTYAPKLSFEFFPTRTPEGRAKQVVTRKQLSQFRPDFFSCTSGAGGSTREGTLQTVQDI
LNEGTPAAPHLPCIGMDAGEIKELLQQYKQMGVRHLVALRGDIPSGIGSGMGGLRYANEL
VELVKNEFGNDFHIEVAAYPEYHPQSRSAEDDINHFVRKVRAGADSAITQYFYNADAYFR
FVDDVQGRGVDIPIVPGIMPVASFSKLARFSDACGAEIPRWLRLKLQSYADDTAAIKALA
LDVVTEMCARLLREGAPGLHFYTLNQAGLSSTICQRLGY
>A0A2V4I5Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. LB-090624|TrEMBL
MSLLKTALREQNFVCVMEFVPKASAERFTAMQAIMARGHLCGWPMTVAIGDRVGSPLDMS
PLDALASFDTPVPALPHFSGKDRERHHLLAQLQHMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQAAPRPMLACLMSLTHGRAAMLDHVAGVTVTPSMREMLEAETAQSK
AFALARSVDRLALQIIGTKLMGYAGVHLSGIHGLQQLLALEERLEHWQAQVHTLEQWAPA
WHASWQMPGLPAVTFHPPQANWRDGESRVDASFKEKTRYHLMHGMHALLFSRRNSLSKAF
GWAVRQPVWATRVGAHVLHTLERSVKRPLAGCDTCGHCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVGQTAVLTERLIPCIEVETRHRSSWPQWFAAQTP
RRVSPQPAPRTQPES
>A0A4Y9MAE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. TF02A_35|TrEMBL
MTPTVRELLATERPTWSFEFFPAKTPEGDVQLWTALRELERLRPSFVSVTYGAGGSTREG
TLAVTERIATETTMTPLAHLTAVDHSVAELRHIVSRLAAAGVRNVLALRGDPPGADPQAD
WVAHPEGLQYAAELVELIRSIGDFSVGVAAFPERHPRSPDLDSDVDQFVAKCRAGADFAI
TQMFFRAEDYLRLRDRVAERGCDVPILAGVMPVTNVRQITRIVQLSGQAFPADLAERFAA
LDGDRPEDRAAVRALGVEVATDLCRTLLDEGVPGIHFITMNRSTATREVFTNLVDRSEAV
TP
>A0A3S0SJG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium chutanense|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWQTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKDETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGVSIPIVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIGDFHLYTMNRSPLVSAVLDNLGLSRRPAKSAGAAA
>A0A519BF80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Acididesulfobacter guangdongensis|TrEMBL
MTKNRFKDKLENNEFVYTSEVSPERGTDLSKIKIILKSLEDKITAFNVTDNQGANMKMSS
LAASVFIKSIGGEPIFQQTCRDRNRMALESDLLGASALGINNVLTLTGDYITFGDHKHAK
PVYDIDSVNLIEIIKGLNSGHDMNGNILNGKTDFYIGAAVNPESNPLEPQLMKFEKKIKA
GCNFFQTQAVFSVENFEKFYDYYKNYNDIKIIAGIFILKSAKVARFMNKNIPGIYIPQSI
IDELENSSSPLQTGIEISARIAKGLKNKVNGLHIMAFGVEDSIPDFLKSFKE
>A0A7C7PRF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquificaceae bacterium|TrEMBL
RDMPDFRPEGGCGHAFELVKLIRSKFGGHFSVGVASYPEGHPESPNMEWEIRFFKEKVDA
GADFSITQMFFDNRYYYEFIELCERAGIEIPIIPGIMPITNFKQVRKFASMCGATVPNYL
VEKMEPVEDKPQEVAKIGVEFAIKQCEDLLRNGVPGLHFYTLNRSKATLEIYDAIKDLCA
L
>A0A674CEM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmo trutta|TrEMBL
MVNQVQRVEDTWRTCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKAKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKMDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPDEIMRVIEPIKDNDAAIR
NYGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWNEDPRRTLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKNELDKVN
RRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPQEEQPSKNQ
AVRSTELSVEL
>A0A7C6MFD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium sp|TrEMBL
MPETIVDRLRETDRPTFSVEFFPPSDDAGVQQLIATIEALQPLEPDWVSVTYGATGASRY
KTFAAVGAIRGQTAVSLIGHLTIAGQSAAEVVRAIQAYQRLGVTHILALRGDPPAGGSFR
AHREGLRTATDLIRLVKSLGDFTVGVAAFPDGHPESDLELDARILLAKEQAGAEFAISQL
FFDAGSYAALVERFRALGGTMPIIAGIMPITVPGQIERFAGLSGSRMPAAFEAQLREVAD
DKAAFRARGIDLVTQLCRDVLAAGAPGLQFFTLNRSTATAEILGRLRAEAAVAAS
>A0A667WY58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myripristis murdjan|TrEMBL
MVNQVQRVDGNWQSGKSDSSGASNSGGESSKESSRCSTPVLDADRSDRLRDKMLRRMESG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLETILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAT
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRAETF
LKFVRDCRKIGIMCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIEQAVEMCRLLLESGEVPGLHFYTLNREVATIEVLRQLGMWIEDPRRPLPWAMSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLKMWGEELTSEDSVFEVFTCYITAQPNHSGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSSDPLVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRV
NYHIVNVQGHNLTNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDMPPEDLLCPF
>A0A2P6U1W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorella sorokiniana|TrEMBL
MARIIDKLNAKIDAGELFFSFEYFPPKTDEGVANLKERQTRMAALGPTFCDITWGAGGST
ADVTLDVARAMQQEVGVETMMHLTCTNMPVDKLKDALTKAKEYGICNILALRGDPPKGQD
HFEQVEGGFACALDLVKYIRAEHGDYFGIGVSGYPEAHPDVIVEDGEQMHKNYWADIEYL
KKKIDAGADFVATLSARRASLLTRLLYASIFVQIDAGADFVVTQLFYDVDRYQQFVKDCR
SVGISCPILPGVMPIMTYGGFKRMTSFCKTAVPQHVADTLEAIKDNEAAVKAYGISLGTM
MCQRLLAGGAPGLHMYTLNLERSAVAILENVGLVPKKEAAKADRQLAKSP
>A0A7S2VBK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amphiprora paludosa|TrEMBL
FTCALDLVKFIREELSFGKELGVSVAGYPEGHPNAISEIKDPSTLTDTEKLRASEFNGIT
YACLDADYQKELVYLKEKVDAGSDFIITQMFFDATVFLQFVQDCRAIGIACPIVPGIMCI
NAYAGFVKMTQFCKTRVPPALRSKMDELNALPKEDAANAIKQFGIDFGVEMCQQLLDGGA
PVLHFYTLNLEKVVYGVMDGLGLSQNAVAATDEADAALQAAKGSAWARVGDIVTSPQFEG
EGTVLEMDAATAQAKIEVSADKSVVTLEKGQYTKKF
>A0A7X7XP49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium sp|TrEMBL
MQRPTIAERLNETGRPTFSFEYFPPADAAGAFTLLDTVVSLKELRPDWVSVTYGATGATR
QRTFDAIRAIQRHGGVRTMGHLTVAGQSRDEVAAAVDTYAALGVEHILALRGDMPEGPTA
PFVPHPDGLRTATELVRLIRERGDQQIGVAAFPDGHPAQFDKDLDARILLEKEEAGATFA
VTQLFFRAESYVELVDRYRALGGTMPIVAGIMPVTHLGQIRRFQDLAGAGMPADLTAALQ
AAADDRERFREVGIAWMTRLCDDLLAAGAPGLQFFTLNRSKATSEILARLRRLPPRRA
>A0A2W2BPU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aestuariivirga litoralis|TrEMBL
MRLAIRSGSMADVTGIMVNSGTTTTAMCWGSCLGGSPNIGGGNSCFDPFCAKFGHCPPAS
CRRWKTTRRDGSGRIHHGGVANIRAGPFWLAQSPATSTEPVFPMNAPITAAGSSTASFLR
LSSIEITPKQVEKLALLKEKLVPGCRVFVALIDAGDLGAQIEAVKQLKAAGFQPVPHVPA
RFVKDEADLRARIKALAEAGSDTMLVLGGGAPEPIGQYDAAIQLLNTGVFQANGVKTIGI
AGHPEGNPDITKVHGEAVLVKALKEKQAYLKANGLDGFIATQFLFEAGPVTEWARGLRAE
GIELPIYVGIPGPATIKTLVKYAAMCGVGNSARFIRKQALNITKLLTVNTPDDFVAGLAQ
VHYGQPDLGIAGPHLYPFGGFDKLFDWLATVK
>A0A3R6MHM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF22-10|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPTLSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPALCIGAACYPEGHVESVNKTVDIDHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A2I0NCH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetae bacterium HGW-Spirochaetae-6|TrEMBL
FFNNEHYFRFYELLRKKNIQVPVIPGIFLISSYKQLQRIEELSGSDIPKKLAEDLSRHQD
DPDALRQIGVEYALSQSRSILEEGVAQGLHFYIMNRQDMIKELADSLPSF
>A0A543FLP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium kyungheense|TrEMBL
MSIDLSTPPVPVSFEVYPPRTEAGWPVLHETIRHLASVDPRFISVTYGAGGSTGGRSLEL
LTHIRRETTVEPLAHLTCVGSTWAGANALIREFLDAGITSFLALRGDPPDGATEDEAFLG
DLESAAQLVQLIDRVQAEREPYAEAPIPGVPGAARVDRRTDVDIAVAAFPSGHPRSRHAT
EHIDALLAKEAAGATLAITQLFFDADDYLGFVQRSREAGVTIPILPGIMPITSPARLRRT
LELTEVPRPDALAAALEAEETPEARSAVGIAHAAALAQAVLDGGAPGIHLYAFNNHETVL
AVLRDAGILSADARMRLAVS
>A0A0Q9TAA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Soil805|TrEMBL
MTQGRGRMRARLESGEPSFSFEFFPPKDAEGEEQLWRAITELEPYDPTFVSVTYGAGGSS
RDTTVRITGRIARETSLVPVGHLTCVGHTRDELEGILDSYAAAGVGTVLALRGDPEDGPR
AEWVPTAGGLAHASDLVELASRRGDFAVAVAAFSLGHPSAESLEHDARVLLAKQQAGAEF
AITDMVFSADDYAGLLERSSAVGVDIPVLPGIMPILNLRQVSRMAELSGHPVPEAVRRRL
APHEQDPAALRAEGIAMAAELCEALLAAGAPGLHFYTLNRSKATREIFTALRITV
>A0A349GJ77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter adhaerens|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYREHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>S9RU14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia sp. AU12-08|TrEMBL
MNDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILNTYRENGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGDAFHIEVAAYPEYHPQARSPKHDLDNFARKVKAGANSAITQYFFNADAYFQFVA
DAHKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWVAKRLESFGDDRESIRAFGLDV
VTALCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A178FFM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton violaceum|TrEMBL
MEKISDKINALPKDAHYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEETKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFNYAVDLVRYIRKKYGDYFCIGVAGYPEGHADESHPEVQDPLKDLPYL
IEKTQAGADFIMTQLTYDIEAYKKYEALLRNHESGTFKTIPIIPGLMPIQNYHTLTRVTK
LSHAKIPPQILAKVEACKADDEAVKRVGVDVVSDLVENIKKVATPGHRGFHFYTLNLEKS
VSFILERCNLIPPSSEAPSGSELDFESAVYAASGASNGVATPDGRSTNVNRLRASSMNSQ
PHNRVIVDRLTRASDRSERSSTVHETSAQTAGYPALNPPNRNTALQISEGLGSLGREATW
DDFPNGRWGDARSPAFGEIDGYGPSLHVTAQVARKLWGTPTSRDDISNIFKRLLSGELHV
VPWSEGGAGEEGGLNPETATIKAELLKLVEGRGWWTLASQPAVNGVRNDHPVFGWGPRGE
GFVFQKAFVEFFCSGDDFHSKLKPLLQSYGHDEFAWFATNAKGDFQSSTSPETSTQPPTD
PSEVPFDADPLTEMDNGSVNAVTWGVFRGKEIVTPTIIEAVSFRAWGEEAFGIWEEWRRV
FPRGSPSEKLIREIKDDAWLVCVVGQRFGAGGDVGKESNEEDGKLLWKVLAGE
>A0A259S160|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halothiobacillus sp. 13-55-115|TrEMBL
MGSEAIMHTPLSCEFFPPKSDEGALKLRAVTEQLTAALKPEYFSVTYGAGGSTQDRSFAT
VQAIQTESGVPAAPHLSCIGSTRASIAAILDQYRALGIKRIVALRGDLPSGMRDPGDFRY
ASELVAFIREHSGDWFHIEVAAYPEFHPQSANARADLLHFKQKVEAGADGAITQYFYSIE
AYARFLDDCEKLQVTIPIVPGIMPISNYTQLARFSDACGADLPRWLRKRLEAFGDDMDGL
RAFGHDVVTRLTADLVQAGAPGLHFYTMNQAAPVINICRDAGLMSC
>A0A651EXC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaeraceae bacterium|TrEMBL
MHIADIFTERGQTFSFEFFPPKTADSAASLFDNIAELIPLKPSHVSVTYGAGGGTRKVTH
DLVVRIKQQTPLEVMPHLTCVGHTEAEIYDILEGYASAGISNILALGGDPPRNAPNYDRS
LDAFRYASQLVQYIRKFKDRHAGTAIGDPRGFGIAVAGFPEGHPSTPNRVKEIEHLKAKV
DAGADCIITQLFFDNRDFYDFRERCELAGITVPIVAGIMPVTSSSGLMRMADLAAGARFP
ARLLRAISRCNGRADATRRVGIHWATEQCRDLLDNDVAGIHFYTLNKSTATREIYASLGV
ETSLDLAADIPAP
>A0A1Z5JYK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fistulifera solaris|TrEMBL
MTKIIDILTNHDGDKPLISLEYFPPRSDVGVQNLHSRMDRMKNVLSPAFTDMTWGAGGST
AELSLDLALHAQKTGHLANLHMTCTNLGNVDPKEAIYKALQTAKEGGIRNIVALRGDPPA
GETEWKAAEGGFHCALDLVKFIREKFGDDFGISVAGYPEGHPNAITEIADPSTLTPEELA
RSSHFDGKTYCCLEADYKKEMDYLKQKVDAGADFIITQMFFDVTIFTTFVADCRKWGIQC
PIVPGIMCINAYAGFRKMTQFCKTRVPQFLDEKMEAIKDDAEAVKEFGVTFGAEMCQGLI
DSKTTPVLHFYTLNLEKVVYGILDKMGVTQNALAAADEADAHSQVAKGSAWARVGDKVST
QYGEGVVVEQIASTGVAKIELDKWIMAGGQKPVAYLQKGQYTKIF
>K9TUU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroococcidiopsis thermalis (strain PCC 7203)|TrEMBL
MHNTTRLNSFRKAVKAREFLVTAEVAPPKGGDPSHMLQMAQALKGRVHAVNITDGSRAVV
RMSSFASSVILSQQGIEPICQVACRDRNRIGLEADLLGAHALGIHNILALTGDPVKAGDR
TDAKSVFDLESVRLLQLIGKMNQGLDCDDKPLTDGATDLFVGAAVDPQCKSWSGLQSRFE
RKLAAGAQFFQSQLITDFDRLEKFMTQIASGCNKPVLAGIFLLKSAKNAQFINRCVPGVN
IPEHIIDRLAQAKEPLAEGIKIAAEQVQIARQLCDGVHMMAVKREDLIPQILDLAGIPPV
VSYSLPSQVVSSLR
>A0A1B9Y834|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. CBo1|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEATKGGHASAMDLVHQINDLGRGKYLHNQDEECEEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVTKAREMGITVPIIPGI
KPIATKKHLKVLPQIFKIDLPEELINEVENAKNNEAVKQIGIEWAINQCRELLDLGVPVL
HFYSMGKSDNIKKVAGELF
>A0A2D6Y3Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. ARS1019|TrEMBL
MDLNLTSALQRAVESGGMVLTAEVMPPRGADPSHTLAMAEALRGRVHALNVTDGSRAVMR
MSSLAVCRLLLDAGLEPVWQLACRDRNRIALQADLLGANALGIRNLLCLTGDPVRAGDQA
DARPVNEFESVKLLQQVSALNRGEDPVKGALSDGATTLFQGCAADPHSRSWSGLQRRLTR
KCEAGARFVQTQMVMDPAVLERFQNELAKPLELPVLAGVFLLKSAKNALFINRMVPGACI
PDDLIQRLDQATDPAQEGIAIAAEQVKRYSGLVQGVHLMAIKAEERIPQILDRAGVSLPP
G
>A0A840EG20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinibacter ruber|TrEMBL
MNLTEQLTGDGSVASFYGTVPPREGTSDSEMRAIAGKLSSRLEDFSTSALLVYDVQNEDG
RNGKPRPFPFVPTVQSRRYAALLREVTGRPVICYKAAPAHAGDNFQKWLKETRRDFNLRY
LSLVGSSSSDGDAPGPTLEKATQMTATVEDPGFEAIGGVTIPERHMAKGNEGRRLLQKTE
QGMDFFVSQIIYRPGATVQMLQSYDRRCQEEGIDPSLLVLNFAPCGHRKTLQFMRWLGVD
VPDAAEERIFSADDPVSASVKLCQDNLAQILKRTADLSVPLGVAAESVSKRSAEIDASVE
LLGVLQETVSDVSSEVVSVST
>A0A6J1T7A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankliniella occidentalis|TrEMBL
MRELCVVPEAASHQDGGCDEARADTRTSAATASATSLPSGSSRSRTDFDIPKIIAEKIRS
KSFFWSAELIPGTSPHLQALLEQSLKDIANHAHNAPSFVSVTWHESHLKEIKVGGSTRLQ
HPALELSKYLQQKFGIPALLHLSAGNLKRTQVVRILEGCIDSGITNILALRGDQVRDVEA
EFHHASDLVHFIKQVFGSKFKIGVAGYPTGHPEATSLEQDLLYLKKKVDEGADFILTQMI
SSVDEYYTYLKHCFNLGVTVPIIPGLYLIQSFDSFKKFISTCQISVPARMYQDFKKIQDI
NKEKQYGLRLFQDLIRGLQKTSYCVGIHIFTLNRYVTALLQTRCHFLENFLE
>A0A7W7L0K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas euvesicatoria|TrEMBL
MDFGSFPLDQCVVAMPPNHHDKTARPVISTDTPNFASTVTEAYSLEVSAKDIGALTNAAP
RILPGCAMFIPYLPGQNEAVRLAAAQMVRRLGFEPVPHLSARRIGSLGELQACIARLVDE
AGVTRCLVIAGDPSTPKGPFPDSVSLIETGVFERSGIRTIAVAGHPEGHPILRTTEQWDV
LERKCRSIQERGMAPLIVTQFGFDADIVVTWLEALRARGMTHPVRVGVPGPASVAVLARY
AASCGVGACASVLSNYGISIGKLFGNAGPDRFVDRLASRLTKAHGDVRLHLFPFGGIAQS
VEWVAHYRSRASQQDRMRSVRADQA
>F6DRR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforamulus ruminis (strain ATCC 23193 / DSM 2154 / NCIMB 8452 / DL)|TrEMBL
MKLSTLYRQKKPVISFEIFPPKSTLPVESIFSTLEGLIQLNPDFISVTYGAGGSSRERTK
EIASKIKNQYKIETLHHLTCVGHSASELRQIIKDLQAENIENILALRGDPPAGVEDYDFS
QCQFEHAVDLVKYIKANSDFSVAAAAYPEGHAHCTRLSDDLNWLKYKVDQGVDFLITQLY
FDNRVFYNFLENARRIGIKCPVAAGVMPVINGKQIKRIISLCGASMPAKLLMLVDQYGDN
QEDMEKAGIEYASRQVEDLLRNGAEGIHLYTMNKPQQITEIVKNVGLA
>A0A444MT46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter gilvus|TrEMBL
MKITEHIQNAAGKTLFSFELIPPLKGESIQGIYNAIDPLMEFKPPFIDVTSLREDYIYKQ
HETGLLEKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLQFLGIEN
VLVLRGDARRGDASFVPTPNGHCYATDLLQQVTNMNKGIYLHENHEGILKSDFCVGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGAGFIVTQMFFDNQKYFDFVNSCRASGINVPIIPGLK
PITTSKQLVNLSKTFHIDIPEGLSDAIHDCKEEKNVKDIGIEWMINQCKELMKFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A7V9Z0Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus calidus|TrEMBL
MGFLDDLAQQILIADGAMGTLLYSHGVDSCFEELNLSRQEEILYIHKAYIEAGATVVQTN
TYGANYVKLSRYGLEDQVKEINQAAVRIAKQAAKGRAYVLGTIGGLRSIKKTAITLEEVK
RTFREQLYALLSEDVDGLLLETYYDLEELLTVLSIARKETDKPIVAHVTLHEVGVLQDGI
HLADAFDQLETFGADVIGLNCHLGPYHMIRSLEEVPLPKKAFLSVYPNASLPDYRDGRLV
YETNPSYFEETALAFREQGARLIGGCCGTTPKHIAAIAKALKGLKPVIEKKVKERNIVVS
VQASSPNKKPSLHEIVKQRRSVIVELDPPKKLGITKFLEGATALKESNIDALTLADNSLA
TPRISNVSLGMIVKEQLGLRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIQLISQFNEGLSYSGKPLGEKTNFSIAAAFNPNVRYLDKAVER
LEKKIRCGAHYFISQPLYSEKQIEEVYEATKHLSVPIYIGIMPLTSARNADFLHHEVPGI
ILSNEIRARMAACANDPIQSTREGIAIAKSLIDAAFELFNGIYLITPFLRYEMTVELANY
IHEKEKAGQERKIFNV
>W8BHT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceratitis capitata|TrEMBL
MHAPISSSSSSTTPTPSGAHILPTTPSQTFHPLLVRFSSKESTPQQGKLAELFRQKVAAK
EFFYGIELSARSYGKQPTVLDYDKFGALLPLFTSLVWLGREYANVEDVTAVESVSLGRQL
YEHVVVMPHFTCYRADSKRLDEFLTLNFSNVLALRGDQVAPQQQFPHAKDLVQYIRSKRG
DSISIGVGGYPEGHPESKTMEEDMLYLKEKVDAGADFIITQICFSPEAIISFVQKCRANG
ITVPIIVGVIVPDNMRILQFITNIIQVVIPEEQLSKYQALEDNPKALQAYAVENAVKMVK
LLLESNLDIYGFQFFTMNRLKNIRLVVHEIHEYFNTKNI
>A0A1G5SBS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas mobilis|TrEMBL
MQSQKKFPPTFSFEFFPPQTEEGQQKLRATRIQLAQFCPKFFSVTFGAGGSTRDRTLATV
LEIQAEGYPVAPHLSCIGSTRENIRNILETYRTHGVTHLVALRGDLPSGMAQAGEFRYAN
ELVAFIRKEFADIFQIEVAAYPEYHPHTRSAQEDFANFRRKVEAGASAAITQFFYNADAY
FHFIDMCERINLDIPVVPGIMPIGNFSQLTRFADSCGAEIPRWIRRKMEGFGDDTASIQA
FGLDVVTALCNRLLEAGAPGLHFYTLNSAVLSTKIWQRLSL
>A0A1I7I5U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter akesuensis|TrEMBL
MKVTDHFKNANGKTLFTFEILPPLKGENLQTLYSHIDPLMEFNPPFIDVTYHREEYIYKQ
RENGLLEKRSTRKRPGTVGICAALQNYYKVDTVPHLICGGFNREETENALIDLHFLGIDN
VLVLRGDCVKSEARFVPEQGGHHYASELIEQVVGMNNGIYLDDEQANTNGTDFCIGVAGY
PEKHFEAPNLRSDLRWLKRKIELGADYIVTQMFFDNQKYFDFVKLCREEGIEVPIIPGLK
PLTTKTQLSLLPSLFHIDIPCDLADAVEACTDNKGAAQVGVEWAIKQSKELMDFGVPCLH
YYSMGRSGSVRKVAEQLF
>A0A4S4KHD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hermanssonia centrifuga|TrEMBL
MEKGSIDVALKEAKDRGIRSLLCLRGDPTRGDETWLPTDARFQHGIDLVSYIRSQPEYTD
FDIGVAAYPDGHPESDVNEQDEIEYLKAKVDAGASYIVTQLFYDVDGFIRWEKKVRDKGI
TVPIIPGIMPIQTYASFLRLTKLCGTRVPPSLMEDLVPIRHDDQKVKDYGVKLAIKMIQR
LTTEAEVPGVHICTLNLEKSVQRVIEGLGWSGSSLKYTNKLIADVSGTATPASHPELELV
ITPHNATDSATTQLAVGPATETEAGKGELNNAATWDDFPNGRFGDFKSPAYGVSNPWGTS
NITRNQALSQWGYPKTVDDISKVFLRYLHSKSNSTPFSPEPLSPESLLIIRHLERLINKG
WWTVGSQPAIDGVNSSDEVVGWGPKGGYVYQKCFVEFFVEKEDIDKIEEKVRERGQGWVD
YFAGNLEGECRTNVSEGGRNAVTWGVFPGQEVAQSTIIEKESFLAWKEEAFSTWAEWASY
YPPDSAERKILEDVRQRRWLVSIIHHDYKDPDALWTFLFNED
>A0A2V1H991|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. S1B|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEQTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLDAAPHLTCIDATPSQLIDIATDYWNSGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMSSMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>Q72H39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)|TrEMBL
MKIRDLLKARRGPLFSFEFFPPKDPEGEEALFRTLEELKAFRPAFVSITYGAMGSTRERS
VAWAQRIQSLGLNPLAHLTVAGQSRKEVAEVLHRFVESGVENLLALRGDPPRGERVFRPH
PEGFRYAAELVALIRERYGDRVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIGIPILPGIMPVTSYRQLRRFTEVCGASIPGPLLAKLERHQ
DDPKAVLEIGVEHAVRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGLRPASGQP
>A0A3D0GNX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halieaceae bacterium|TrEMBL
MATQQLSYEFFPPKTDAGREKLLSLVIPTLITTNPAYVSVTYGAGGSTRDNTIGTVSAIH
ELGIEVAPHLSFGTDSEDRMGELLRHYQTMGIKRLVALRGDLPSGSGGSQQLVYASELVK
FIRAQTGDQFTIEVAAYPEIHPEAKSYSADIENLKRKFDAGADAAITQYFFSVDAYTSFV
DSCRQMGITKPIYPGIMPITNYDNLARFSRNCGADIPRWLDKKLANFGSDNAALTLFGQT
FITDLCQKLLASGAPGIHFYTMNQIEPIMSIVSELKRAGYFASQ
>A0A1R0G481|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ATCC PTA-122608|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKHAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNAESYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A174KJU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia wexlerae|TrEMBL
MLIPRFLTSWMPESDPVKYTVVSPCSDSVDAQLAKMERKVAAGAEYFQTQAVFAPEKFIK
FMEQAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEELKADKEKTKAGITGVE
IAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A2V8TDX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MGSQRKPFLEFLEQSIVLFDGGIGTELYRRGVFVNRCFDELSLSSPELVRQVHMAYADVG
ADVLETNTFGANRVKLTKYGFGEQTTAINFESARIAREAAGDSLYVAGAVGPLGIRIEPW
GPTSITEAEEFFREQAEALVRGGANLFVLETFSDLNEIAAAIRAARSVSDVPIIASMTIE
DDGNSLEGTAPEVFAAKLDAWGADVVGVNCSVGPAAMLTAVERMAEATRRKISAMPNAGR
PRNIDGRNLYLCSPEYVASYARRFIQAGARVVGGCCGTTPDHIRAIRRAIRTMQPAVRRT
VITVPSPGPGRAVEEVRRADKSGLARALVAGRFVVCVEVLPPKGCDASEVLEGVRYVSEQ
EVDAILIPERPSASARMTPQALAQLLMKQGGIESIVEYGCRERNLPGMQSDLLGAWVLGI
RNLLLITGDPAPAGQYPGANGVFEVDAIGLTNMVHRLNRAIDIGGNAIGAPTAFHIGVRA
KPGASDLDREISRFEWKVDAGAEYAVTQPVFDVGLLEQFSRRIAHVKVPLIASIVPLASF
RDAEFLNNEIPGVVVPEGVLERMRRAESEGHPQQEGIAIARELLGSLRGLVEGALVSVPH
GRYASAIEVLDGLVERRAAAPPRALES
>A0A7C2XLN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurivibrio alkaliphilus|TrEMBL
MKPNFNEYIRERVLLADGAIGTYLYSKGIEPDKNIERLNLADPELVYSTHEEYIRAGSRL
LETNTFGANRLKLEAAGLADKTRQINQAGAALALRAAGNDIYVAGSVGPSGYDFPLPDPD
GAEGEAVRAAFKEQLEALLDGGVDLLILETFSHLDELLLALKVGRELAAEIPIVANMVYP
QQGRTAAGLDALTCGQAALRAGADMVGSNCGRGARALLAAIEKLSGLGANTPLAAFPNAG
FPEIVDHRLIYPAEPAYMARVVGDMVKAGARLVGGCCGTTPAHIQEFGKHLRLKRRPLSR
LGGGAPSDSSPEGRIASVTKPGALLAGLPTDRLPILVELDPPTHLDISGVLLGAKALAAA
GADAVTLGENPLAVLRADNISLAHRIRSEVGIPTVAHLTCRDRNTLGLQSQIMGAHLLGL
DGILAVTGDPASTGDQPGASGVFDIQSFGLIRMLNQFNQGRNPAGREMKGECDFSIGAAF
SYRPCNPDLQIRRLERKAALGAVFAMTQPFFSATAVEEMLERTRHLDILIFPGIFPLISA
RNADFLHHEVPGISIPEELRRKLWGYETVEDQRKAADEFTRELLAAICPLIDGLYLISPL
NRWEVTAELTREVRQAGWTGSGRRFSP
>A0A7Y2VHW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MTAPRISFEFFPPRTEEQQLVLESTWQKLAPLRPEYLSVTFGAGGSTLEATRETVAALSA
STDVPVAPHLSCMANSKAMLRDILVAYRDMGVDRLVVLRGDRPEGQSGPGPFQYANQLVE
FVRGEFGDHFHIEVACYPEFHPESESAETEMFYFKQKVDAGADGAVTQYFYNADAYFSFV
DESRRQGIDIPITPGIMPITNYRQLSRFSAMCGAEIPQWIRRRLEAYGDDGASIRAFGLD
VVTALCERLLAGGAPGLHIYTLNRANASFLLWQRLNG
>A0A2V8RB85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MDDFKELIESDHIAVFDGAMGTMLYSKGVYINRSYDELNLTNPDLVRAVHEEYVRAGAEV
IETNTFTATAHKLQQYGLEGRLRDINVAAARIAREAACGRCYVAGAVGPLGLRIEPYGPT
SFDEAKEMFKEQAAALLEGGVDLFVLETFSDISEMREAIRAVRELSDLPVVAQMTISLDG
NTSFGTTPEVFTARLDEWGADVIGLNCGVGPATVLTAVEKMRPVTTKKLSAQPNAGLPRD
VQGRQFYMCSPEYMAKYARRLIQSGVRFIGGCCGTTPAHIKMISDAVRPLSPRHTGRTGK
LARAVLLEEQTPAETPVLPLEERSNWGRKIARGEFVTTVEVLPPKGCDASKTLESIRLLK
QAGVDAVNIPDGPRAQTRMSAQATAVLVEREIGLESVLHYTCRDRNLLGMMSDLLGAAAL
GLRNLLLITGDPPKMGPYPDATAVFDIDSIGLTNMVSKLNHGLDLGNNPVGSPTSFCIGV
GVNPGALNLEEEIKRFEWKVEAGAEFAITQPVFDVEQLLDFLRRIEHVRVPVVAGIWPLV
SYRNAEFLHNEVPGVVVTPSIMERMRAASEKGKEAGREEGLQIARELLLDVRGAIQGVQV
SAPFNNVRYALDVFEALPEFARRKEAEPAVSL
>A0A521TED9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRSLIKPFLSEIEARVLVCDGAMGTMLYSKGIFLNKCFDELNLTQPNLVLEVHQGYVRAG
ADVIETNTFGANRFKLSTFGLADQRRAINVEGARLAKRAARDAAWVAGSIGPLGVRIEPW
GKTGVTDAEAAFREQAEALVEGGVDLFMLETFRDVNELAAAVRAVRSVSQLPIVAQMTTE
DDGNSLDGTPPETFAPRLEAAGADVIGVNCSVGPAAMLETLERMGRATGKRLSAQPNAGR
PRDVDGRNLYLCSPDYMASYARRFIDAGARLVGGCCGTTPEHIRQIKQAVRQIADVGRSF
SSGPKAAGAEAPAYFPTVARGEKSALAKALAAGQFVTIAEVGTPRGMETGSALAAAKRYA
ALGATAINVPDYQRSAGHVSALALSQLIAASGIETVLHYSCRERSLIGMQSDLLGAHAMG
LRNVLLVTGEPPSQGTYADATAIDDVDSIGLTNMVASLNRGLDIGGQSLGRAAAFHIGVA
VNPNAPSLDTEWKRLDYKVEAGAEYILTPPILDVAAFQRVLPRLRATGLPVIAGLAALET
ARQVDFIASEVSDVAVSADVVARMRAATDPAAEGLAISLEIFNALRSSVHGVAIRGLHGS
PASVERFLEAVRG
>A0A2V9GJY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MGLGVQSRHPSPEEIQDIFHEQALALEERGVDFYILETFSYIEELLLAIDAIRSFSGLPI
VAQLTYAEEGTAYGDVRPADAAAQLKNKNVQVIGANCTLGPQALLPILEELAAVDGLRVS
GMPNAGFPKREGDRIVYPKSSPEYFALFAREAVALGVRLLGGCCGTTPAHIRAMAEAVKS
FRPSKTHPVTQSVETVLRPAPVAHREPESKFWRKLQARQFALCVEIDPPKGLSLDRIFEQ
VDKVMASKKVDAIDVNSGAMARVGMDALIVAGALEARGVETVPHLTTRDQNIIGLQAALL
GAWTVGGVRNVLAITGDPPSVGDYPETSGVYEVDSVGLVKVLSRLNQGTDWAGKTLGGST
NFTIGVALNPVADDLDNEIERFHAKVEAGAHFAMTQPLFDPEHWNAFLKKLGGKPVIPVL
IGIWPLNSYKQALRLNNEVPGMVIPEPLLKTMEAAGTGARDRGFKVAREMLAWARTELAG
AYLIPPFKRYEEILEIL
>A0A8G0T2R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp. SCSIO 43702|TrEMBL
MTTPAVSFEFFPPKSLEASFRLWDTVQSLAPLDPRFVSVTYGAGGTTRELTRDAVGTLHR
SAGLRVAAHLTCVDASREETLGIARDFATAGVKDIVALRGDPPKGTGAFRPHAQGFADSC
ELISALADTGDFNIRVGAYPERHPEARDEQADIDWLKRKIDAGASEAITQFFFEADTFLR
FRDACARAGIDAPIVPGILPIENWQNARRFALACGTSVPQWLDDAFSTAIRDDRHDLLAT
AVATEMCSKLLDEGVDTLHFYTLNRPDLTRDVCHALGVTPKVALREVA
>A0A6N8WGJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MNPLALNSSPSGGSWVKQPLAQLLQQTDSFVTCIELVTSRGIITERSGRRVLDLARGLAR
HPQVHALSITDNPGGNAMLSADTLGTDLIARGQEVIIHLSCKDWNRNALQSRGWKLASEG
FNNILALSGDCPTGGYAGQASGVFDIDSVGLLKMYSDMNAGLTEEGRGEATM
>A0A2W1BY62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicoverpa armigera|TrEMBL
MEAIKVTELIKNKGNFSYSFEVTPDVSEEDIDNLKVDPLFYSVTWHAKSHQCRDLDIDPI
KTASLLRSKQKQVLMHLSCDKMKSDYLTQVLTLCQEKNICNLFVVLGEGYEPDNSDFKST
SEMIKFIRQKTGQYFCIGIAGFPGCPEEKILEIKDKIAIGADFILTQAFFDVEAFKSFKD
RFTRMGIDAPIIPGVFPFETLKQLEGFIRMCRIKVSDDLLEAVNDNEKMDKPCTELIKQL
IENLRSKCTTSHFHFFTINKLENIQKLIEQIN
>A0A7X4E2N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRRIPDIYAAKRATGRPVVSVEFFPPKTPAGEDRLFDEVLPALGEAPPDYCSVTYGAGGG
TRGRTLQIVDRMQREHGLTAMAHVTCVSFTRGGMQTFLDEAATLGIENILALRGDPPADQ
PNFRRPEGGFDYASDLIGVIRRTRSDEFAVGCAGFPEGHPDCAEGKHADWGHLKTKVDAG
AEFVLTQLFFDNAYYFEMVDYVTGALGVTVPITPGILPILNTKQIKRFTALCGATLPPPL
LAELDRLGDDDASVTAFGIDYATRQCEALLAAGAPGLHLYGLNRAHSPLAILRNLGLAQQ
PASA
>A0A7X4D3S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRRSELAAFLRERPRVGDGALGTALYAGGIASRRSFEDLNRSDPDRVRAVHTAHLAAGAE
VISTNTFGANPWKLGRHGLASEVAKINAAGARVARSAVRPGSLVLGSVGPSGEVVGPFDE
EKAPEFAAGFREQIVALVESGVDAVLIETFTSLTEARLALSAAREVAPDIGVIVLMTFSE
QATTVFGVAADQAAGTLERDGADAVGSNCGVGPDTTLTALERMRNAVSLPLVAQPNAGIP
ERTEGRFLYPSSPDYVAHYAKRYLRLGVSLIGGCCGTGAEHIGAVAGVVRAASAGARADR
VKAPARPNTAAPAEEAPAEIPAVPVPERSGLARCLAEGRFAVSVEMDPPRGAEPGRFLAR
VGDLADAGIRFVNVADGPRATARMSAIAFAALLERSGEVETILHYQCRDRNLIGIQSDLL
GAHALGIRNLLAVTGDPPKLGDYPHATPVFDVDSIGLVRILRGLNHGLDLAGNPLGAALP
FHIGVGANPAAADLEGEMGKFERKVQAGAQYCLTQPVYETRLLERFVKDVRGYGIPVLAG
VLPLVSSRNAEFLHNEVPGMSVPQPVRERLAAAPTRQRAREVGVSVARDMVAAARDLVAG
VYVMPPFNRFDLAIRSVTGLV
>A0A2M7PKC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium CG_4_10_14_3_um_filter_34_13|TrEMBL
MNLREKLAAKKFVVTVELDPPKTLNLDKILREINSANFRKVVDAVNVTDCPLAKLRMSPI
ALSHIIQEKIGLESIFHITCRDRNLLGLQAELLGASALGVKNILALTGDPPEMGDYTKAT
GVYDLDSVGLVKMVNKLNNGYEYKGEELKSRTDFFIGVAVNPSAQDLKKEIKRFEEKVSA
GANFVQTQPIYDIEILERFLEFTAHLNIPKIIGIMPLKSYKMIEYLNNNLPEIFIPSVVK
ERMIGKDIGEGIKISQEFIDKIRKFKEVAGIHIFPLRDMDLVCRLLN
>A0A0H2QCD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moellerella wisconsensis|TrEMBL
MSFFHANQREALNQSLAELDGQINVSFEFFPPRTEEMELTLWKSIDRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKDRTGLIAAPHLTCIDASQDELREIARDYWKNGIRHIVALRGD
LPDNSQRPNLYAANLVGLLKSEADFDISVAAYPEVHPEAKSAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLDKFSKITNVRIPTWMRKMYE
GLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPE
>A0A414ZZ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM15-2|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSASGSGN
GATTAPIAHMITSEFNTPSVAHLTCVGRSHADIVAKIDEYRSAGVENILALRGDLPTGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNHPAIAATIMERLG
>A0A2V9QVU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
NIPDSPRASARMSNQALSALLQQQAGIEAILHYTCRDRNVLCIQSDLLGAAAIGIRNLIC
ITGDPPKMGGYPDATAVFDVDAIGLVNIVHNLNRGLDIGGNPIGNGTAFVIGVGANPGVP
NLDEEIRRFEYKVQAGAEYAVTQPVFDLSLLEKFLRRIESYKIPVVAGIWPLVSARNAEF
MKNELRVSVPDSILDRMGKAVNPEAARHEGVAIAREMLIAVRSMVQGAQISAPQSRYSSA
VDVLEALGTSGIGAGALQ
>D9SCR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionella capsiferriformans (strain ES-2)|TrEMBL
MSNSHISFEFFPPQTTEGVEKLTIARGKLAALNPEFFSVTFGAGGSTRDRTLETVTQIKA
EGFDAAPHLSCVGSTRDNIRAILQTYRDAGIRRIVALRGDLPSGMATAGEFQYANELVEF
IRTETGDHFHLEVAAYPEVHPQAKSARDDLINFKRKIDAGADSAITQYFYNADSYFHFVD
ECQKQGITAPIVPGIMPIVRYSQLARFSDACGAEIPRWMRKTMEGFGDDNESVQAFGRDI
VTAMCEKLLAGGAPGLHFYTLNQAAPCMAIVERLK
>A0A1V6CJ09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium ADurb.Bin135|TrEMBL
MSTQSNLERVLKSGTFAVTSECGPPRGADPEVVKKKGSYLLGYVDCVNVTDNQTSVVRMS
SFSACLVLKGVGLDPIMQMVCRDRNRIAMQSDILGAAALGINNLLCLSGDHQKFGDHPTA
KNVFDIDSIQLIQTVKGMRDEGRFISGQEVKGKPNIFIGCVENPFADPFEIRALRLAKKA
AAGAQFVQTQCVFNVEKFEKWMEMVRDLGIHEKIHILAGITPMKSIGMAQYMKNSVPGMD
VPEEQIERLKGVPKEKVTEEGIKIAVETIERVRAIKGVAGVHIMAIEWEEKVQEIVKAAG
LHPRP
>A2BZX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus (strain NATL1A)|TrEMBL
MKSKLQKRLESGLSAITAEIMPPRGGNTTSAISKAIKLKDLVHGFNVTDGSRAIMRMSSL
ALCKLLLEANLEPVLQLSCRDRNRIALQAELLGAHALGIKNILCLTGDPVRVGDQSQAKS
VQDLNSIELIRQVTSLNKGIDPVSDLLPDGPTNLFAGAAADPNCRGFDGLRRRIELKKNA
GANFLQTQMVMDPKVLERFCKEITEPMKIPVLAGVFLLKSAKNAQFINRVVPGACIPESI
ISRLESSSNPIDEGISIAADQVKSFLGIAQGVHLMAVKAEQQIPIILDRANIN
>A0A1H0HTA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. BP1-145|TrEMBL
MHPIMAVANLITKNSDEHQFSFEVLPPLKGTGTDKLFADIEKLCKLNPAFINITTHHSEY
VYKELSDGRFERQRMRRRPGTIAVAAAIQQRFQVPVQPHVICSGATIEDIEYELLDLQFL
GITDLLLLRGDKAKEDRVFTPTPGGHAHTTDLIRQVQRFNEGFFANGEAIKNPGAKFDIG
VACYPEKHEEAPNLEMDMQYLKEKQDLGAQYAVTQLFYDNEKYFAFVDKAREMGITIPII
PGIKPLAKLTQLSVVPRTFHCDIPEALAREIVKCKTDADARKLGVEWTVKQCQELYAHGV
NDIHFYTVGAVDSVVEIVKELRR
>A0A2E1W0E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTSTASTRLDRLPATAGAAAPPVRLIRDIYAEQRGLGQPVLSIELFPPKTLKGNVSLFEH
ALPALQDLEPDFYSVTYGAGGSTRDRTIAIVDRIQREHQTTTMAHLTCISTSRADIEHFL
LDAXKRGIRNILALRGDPPLDDIGPVEPGFEYSYQLVEFIKELGGFSIGTAGFPESHIAC
TEGKHVDWQRLKAKIDRGADFVLTQLFFDNDDYFVFRDYLAGTLGVSVPITPGILPILST
DQIKRFTSLCGATLPAAVSAKLDAYGNDAAAVGEFGVEFATRQCEALLAGGAPGLHFYSL
NKPHAPTRIIRNLGLRG
>M3I2V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter showae CC57C|TrEMBL
MPLLPLKFTARAALLAQILAGLENPLKFDAEQICRSRLIIYPAHAPSQRKFNRKRRGFLH
FKFGNFMLKEKILNKEKGLVLYGLTPPKAEFEESKLRDISDRWTGRIEGINADGLVLYEV
QDESERNDSERTFEFSGTLSPEIYYRDYLSVATPSVFYRVASGYNEDGFRAALAAQSSNL
NVLVGATSSSQKVRLNLARAYEIAGEFENLAVGGVCIAERHAKKGDEPQRVREKIAAGAK
FFISQAIFDAQMTRKFLEDCAAAKITEPIFLTFSTAGNPKTLEFIKWLGVSVPSSVEDRL
NASEDYLAQSCEIIKEIWRELKQFGDENGLNLSANIESVMAKRAEIEASLELAREFRLL
>A0A258ZH81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium 24-53-125|TrEMBL
MSKNLSISFEFFPPQTAEGIEKLNTTRKQLAPLKPEFFSVTFGAGGSTRDRTLETVQQIQ
ADGNSAAPHLSCVGSTRDNIRAILQTYKTLGIKRIVALRGDLPSGMATTGEFQYANELVS
FIRAETGDHFHIEVAAYPEFHPQAKSPRDDLLNFERKVKAGADSAITQYFYNADSYFYFV
EQCHKLGITIPIVPGIMPIGKFSQLARFSDACGAEIPRWIRKTLESYGDDSASIQAFGME
VVTQMGERLLEGGAPGLHFYTLNQAAPSLEIWKRLGL
>A0A563U0J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. MJ1a|TrEMBL
MKITEHIQNANGKTLFSFELIPPLKGHSIQGIYDAIDPLMEFKPPFIDVTSLREDFIYKE
QENGLLQKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLHFLGIEN
VLVLRGDARKGDSSFVPTPNGHCYATDLLQQVVNMNNGVYLHEHYDNMLRTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGAGFIVTQMFFDNQRYFDFVNGCRAAGINVPIIPGLK
PVTASKQLISLAKTFHIDIPEDLSDAIHDAKSEKDVKEIGIEWMINQCKELVKFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A1I1JPH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. 491mf|TrEMBL
MKLLDLLQRGIVIGDGAMGTFLYSHGLQSCFEELNISEPERIISIHKQYVAVGADVIQTN
TYGANEGKLRMYGLEDSVKEINRAAVRHAKAAVTEKNAIVGTIGGMKHIGAVTTTDMERE
FMLLEQADALLEEGVDGLLLETFYDEFELLHAVKVLRKQTNVPLIAQLALHEAGTTQNGN
SVDDVLKQIIEYGANVVGLNCQLGPLRMIESFKTIEIPKYGYLSAYPNAGLPKYVEGRYV
YEGSPAYFEEMVPEFIKQGVRLLGGCCGTTPAHIEAMKRALGNERPVTAKEVVKRAEVIT
AQRVNVADRITLAEKAKKETTVIVELDPPKTLDTQRFFEGAKVLKRAGADAITLADNSLA
SPRLSNMAMGALLRKYDIPILTHLTCRDHNVIGLQSHLLGLAALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNNGRSILGKTIGAATNFSIGGAFNPHVRHIDAAVKRM
EKKIAAGAEYFLTQPIYDAAVIRNVYEATKHIEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRRRMDAHKTSEEAVAEGICIAKELIDIAMELFNGIYLITPFLKYEVTEALVRYIQ
VKKGQKEGMNV
>A0A416JMM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM49-4BH|TrEMBL
MLYQGNIRDYLSKQPLLFDGAMGTYLADKYIQFGGESCEKWNLRYPERIKQIHKEYIDAG
AVAIKTNTFATNAGDHFTAEEVGKVIAAGTQIAREAIEESAGEQILFGDIGPVLIGDEND
AAERYRLPVDCFLEQGVRHFLFETLDNIEGLDEITEYIKQKQPEAFIIVSFAVSPEGLTR
SGCYGRSLYQKMMNVSSIDALGFNCISGPKHLLDLMYKLSREKNTKYISIMPNAGYPAVL
DNRTYYEAHHYYYAKEMYQIAKQGASIIGGCCGTDPSFISEIAKTLQQSPLPGRKTYSAD
GSGRSVHSVVENRQTEQSISVANDGQEVKNYAGKDNLRNTFAAKLACGEKVLVVELDPPV
TPEIDFFMEGAAKYQQAGVDAIDIADCPVAKARIDSSILACKVMRELGLTAIPHMTCRDR
NINATKALLLGLNVEGVNNVLTVTGDPVPAAERGLVKTMFSYNSAVLANHIRTLNEQIFQ
NNPFMISGALNVNAVNFDSQIIHAKRKISQGIDVLFTQPVLTERALNNLKRAREELDVKI
LGGIMPVVSYRNACFMNSEMAGIDVDPRIIEMYQDKDRAQGEELAEQISAQVAQEIAPYV
DGFYLITPFKRVELILRIIKQIRGLLDR
>A5W910|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQVARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQASPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALETRIEHWQSQVQSLEQWTPA
WHASWQMPGLPAVTFHPPQAGWRLGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPLWATRAGAHVLHTLERNVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A6M2ALS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mammaliicoccus sciuri|TrEMBL
MSLKEALKNQILLADGAIGTILYSEGLDTCPESYNLTHPNKIEQIHRSYIEAGADIIQTN
TYGANFEKLQDFNLEHRVKEIHREAVQIAKRASNDHTFILGTVGGFRNIKKSNLSIEAIQ
YHTEIQIETLVNEGVDGILFETYYDLEELLAVLKDTKARYDIPIIAQLTASNTNYLRNGT
PIPDALETLVKAGADVVGLNCHHGPYHMIKTFKHIDLPDRAYLSCYPNASLLDLEDNDLK
YNNNSDYFSDAAKELVNQGVRLIGGCCGTTPEHIKKIKNVVKDLKPIKHKNVIPIETKQY
KKQNKEEPSIKELVQQRPTVIVELDTPKHLDTNKFFDGIQVLEDAGVDAVTLADNSLASV
RISNIAAASVIKQKYKIRPLVHLACRDRNLIGLQSHLMGLSLLGINDILTITGDPSKVGN
FPGATSVFDVNSSGLAEIITQFNQGINADGDTLRSNTNFSVAGAFNPNVRRLEPAVKRLE
KKIESGMEYFITQPIYEPERVKEIYEATKHIEAPIFIGIMPITNYNNALFLHNEVPGIKL
SDTVLNAFEKVKDDREATRELSINLSKQLIDAVHQYFNGLYLVTPFLKYDLTVELANYSQ
LKTGTQTKEAIL
>A0A2U8W601|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium durans|TrEMBL
MPASTYRASREGCRPIRVSFEFFPPKTEEMERTLWSSIERLAPLHPSFVSVTYGAGGSTR
ERTHNTVARMVRETSLKPAAHLTCVNATKDEVDEVVRSYWDVGVRHIVALRGDPAEGVGT
AYAPHPGGYQHTCDLVAGIKRIGDFQVSVSGYPEKHPEAASLDADIDALKAKVDAGADRA
ITQFFFENDVYLRYVDRVRARGIDIPIVPGILPVQNFKQAANFARRTGASVPEWLAHRFE
GLDDDVDTRRLIAGAVAAEQVLDLVDRGIHDFHFYSMNRADLVYAICHLLGLRAERPVAA
ERAAA
>A0A4R9LCI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira vanthielii|TrEMBL
MHISQVLGKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEQTGLTIVSHLTCVGSTKDEIRDILKRYEKSGIHNIMALRGDPPKGQTEFQKT
ENGFNFAGELVGFIKKEFPQMGIGVAGFPEGHPSTPNRLKEIEFLKWKVDQGADYICTQM
FFNNNYFYDFVERCEIAGIKVPIIAGIMPVTSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDVYAENVGIHWATEQVRDLLDHKVAGIHMYTLNKSKATRKIYESLGIRNFDSIG
>A0A426UAG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. RP5T|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNILAVR
GDPPGDPMGDWLAHPQGLTYASELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVANFVD
KCRAGADYAITQMFFQPESYLRLRDRVHAAGCETPVIPEVMPVTSVRMLERLPQLSNASI
PSVLKERILTAKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A396MDB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. AF15-40|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTSSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>A0A1U6HT59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium mathurense|TrEMBL
MTTPIIHPNWARPPLNMVDGYSLEITAKDVESLRAAAPGILPDTPIALTFLPGEDFDARV
AAARTVRELGFEPMPHFSARRITSRDEFERYLAAVTREAGVKRSFVIAGDPSEPEGPFAD
SAALIATGEFERNGITAIGIGGHPEGHPNMSNEECWQVLEDKCKAIAARGMAPLIVTQFA
FDADAVLSWLKELRERGIEAPVRLGVPGPAGIKTLMRFAARCGVGASASVMAKYGISITR
LIGSAGPDKLVKALEQGLGKEHGPVRLHFYPFGGLEKTVAWINEFARKN
>A0A1F1QJE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. HMSC08G10|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMAVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKEELRALIAQYKAAGIKRIVALRGDLPSGMGMAYGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQARNFESDLTNFVHKVKAGANSAITQYFFNAESYFY
FVERVQKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7S2XSB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Attheya septentrionalis|TrEMBL
TEAGLDNLLTRMDRMSSRLDPLFVDVTWGAEGSTAAKSIAVASYAQRYCGVDVLLHLTCT
GATTTREQLARFLDQAKSCGVHNILALRGDPTPQKSQSGIIGWQPDDVS
>A0A4C2ESX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula mannanilytica|TrEMBL
MALGTRAVSDPQGVQTLLTSARFELMPFESFDEEITHLPDDATIAITTSPQLGIERTVEK
TEEAAAMGYDVVPHIAARYVEDRAQLEGIAERLKQAGITDIFVPGGDREEPAGEFESAHD
LLTVLADTEYSFEEVGITGYPEGHDFIDDETLAESMAQKAPYATYIVTQLCYDPDTVLEW
VEDIRARGIELPVEIGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDDLIDGLAPYVDDDEYKIRGVHIYTFNQTPDTEKWRHKRLES
>A0A243F6L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar kumamotoensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKHAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7K9BZ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psilopogon haemacephalus|TrEMBL
MVNETQHSSASSSSKSDGGSSSGSEGSKDSSRCSTPVLDADRHERLREKMRRRQDSGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDVCVAGYPTGHPEAESYEEDLKYLKEKVFAGADFVITQLFFRSETFFKF
VKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLQVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTCEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6A7BV23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piedraia hortae CBS 480.64|TrEMBL
MSQKITEKISSLPPNTPWTSLEFFPPKTAEGMSNLRARLIRMNKTLHPLFVNITWGAGGS
TCDKSLELAEFTQRELGITTCLHLTCTNLSRDVIDRVLSRAKEIGVKNILALRGDPPRDE
HPTTGEGTLPSPPKQKFNHAIDLVTHIRLHYGGYFCIGVAGYPEGHSDHTHPLTQSVSHD
LPFLESKLHAGADFIMTQLFYDVDAYTCFQNLVRGRFPDVVIIPGLMPVQSYQIFARTTK
LSHVKAPGWVTDALGEAKGDDERVKTVGVEILTKIVGTLRGNGVRGFHFYTLNLEKVVTQ
LLQQAELITERDEGRIASREATWDDFPNGRWGDVRSPAYGEIDGYGASLHADFPTALRLW
GRPASPADVSEVFERYLNGVIESMPWSEEPLQTETVMIRGVLLKMVEKGWWTVASQPHVV
GVESEDAVLGWGPKGGKVHQKAFVEFFLPPNDWRRLEGVLKRERGLTFFAGNKAGRLVCS
DGEEVNIVTWGDFPHRGRLTPTMIDKVSFKSWCEEAFDIWGEWKRVFMRGSESARLMDKI
REEYWLVNVIMDDVERGDELWEMLLKV
>A0A3Q9P1J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium linens|TrEMBL
MSQSTLRTLLSTARYEVLPTAGIVDRIEEYVAPGREITVTASTGLTLEATLSTAEQLQAL
GFRAVPHLAARMIHGRPELTEIVDRLAEAAVDRIFVPAGDATPPAGGYVGAHDLLVDLSS
MAAPFRHIGVSAYPESHPIIPDDVTVQAMWDKRDYATHLVSNLCFDPALVAAWVARVRSR
SIELPLVLGIAGKVELAKLARVATKIGVGESTRFLRKNTATFTRMAKPGGYNPRKFLDKI
GPVLDDPDMGIAGLHIYTFNQIKDTEVWRRKQLAALGGAEEVSTAW
>A0A651F651|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micavibrio sp|TrEMBL
MEKWKTGEIVSGFGTIPERTAEDILGHTALSLPFIPPGDSNIGVSFEFFPPKTEKMEAVL
WDSVQQLAPLGPRFFSVTYGAGGTTRERTHDAVIRIQKETAIPAAAHLTCVGATKEEIDE
IAREYWQEGIRHIVALRGDPPEGAEKYKPVAGGYAYASELIAGLKNVADFEISAAGYPEV
HPEARSPEDDLDNVKRKVDAGAARIITQFFMEPEFFLRYRDRLASAGVHVPVVPGILPVT
NFKSMKKFAAMCATHIPEWLALLFEGLDDEPKTRNLVAATVAAEQCRVLYKNGVTDFHFY
TLNRAELSRAICHMLGMREQSVQTA
>A0A6B8TLA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium xerosis|TrEMBL
MSDFPPPAVGRQVPVRHALTLPSPGPVPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFA
SVTYGAGGSSRDRTLRIAERVSREPLTTLVHLTLVGHTVPELREILRAYLDRGLTNLLVL
RGDPPGDPLGDWTPMEDGLSYASELIEFIRSEEEFADFEIGIASFPEGHFRAPDLESDTR
YTLAKLRAGAEYSITQMFFDVDHYLRLRDRLAAADPEHGAKPIIPGLMPITSMRSVRRQL
ELSGSVLPAALDERLTRAAAGDEEANRDEIRKVGIEVTTEMAERLISEGAPGIHFMTLNF
ARATQEVLNNLGMAPAWGTGQDMLRGGF
>A0A2E0Q8Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micavibrio sp|TrEMBL
MLDGYSYIAYKYLYMRFSAEFFCPHTADEKRELLKLTESLSTYNPSFFSITFSTKTQEFD
SSLKLAQTIQNHTDTPVALHMSCIGTPKDILKQRLDKALNAEIQHIVALRGDWPRSREDK
PPQGNEYCHYASDFVALIKSHAPAIKISVGAYPEKHKQAETLGQDIQHLKQKLDQGADQA
ITQFYFDQLYFDDFVKKTAQAGITKPIIAGLMAISDFELISRFAHGAEAKIPETITRRFA
DLSSEKMIEEGTIFLQEQIITAQKSGVEEIHLYPMNKPNPILKALDHFFA
>A0A1Z5IRM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Secundilactobacillus pentosiphilus|TrEMBL
MKVVDCFKERPVISFEIFPPRPSASEKAIERFYDNLDVLASLKPAYISVTYGAGGSGKNS
GTLDLCRYIKKTYGIEAVPHIPGIHFTKAAVKAYLAELKAANIDNILALRGDLPQDGVIK
GDFQYASDLVSEIKRDGDFNVLGACYPDVHPEAKDSVDDIKNLKCKVDAGVSQLITQLFF
ENEHYYRFLERCELADINVPVQAGIMSVVNERQIKRMATMNGVGLPQKFLKMMNHYQDNP
VAMRDAGTAYAIDQIVDLLSEGVDGVHLYTMDNPVVTKRICGAIETLI
>A0A2H0LFC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG11_big_fil_rev_8_21_14_0_20_64_10|TrEMBL
MRLEQLYRSGKPEISFEFFPPKTAEGTEKLFGDTIPRLKKFQPALVSMTYGAGGTTRELT
LELCDRLKRQADLETMCHLNIVGQSRTQIRENLQRLKELGIYNLLALRGDPPRDDPNFKP
HPEGLTSSVELIEEARRLNWFSIAVTGFPEVHPEAKDRAADIAYLKRKVGAGGCVIVTQL
FLDNAFFFEFMEEVKRAGITAPVIPGILPILSAPQIRRFAALCGSTIPPAVEKNLAKYEE
DDAATAQYGVELATRQCEELLKKARVPGLHFYCLNRPEAAEAILKNLGLSPAPQK
>A0A1Q4D816|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. 73-21|TrEMBL
MCADRFRVVCEIEPPTRPGLTHARHQIGVLTPVADAFLIPDNHIGRATVSSIAVANEVRA
MGGRSIACVNSRDRNLLGFRRDLLTAAAYGVESFLFVHGDKPTAGDRTSELTVRTMIDEA
RRATDQPTFEGTAPFRLGVTAGHRRPMAAWKQAADFVFLQVGYSVEAFLRWREQNPTDLP
VHAGVMVLASAGMARRLRASIPDIAIPDALVEQVTADPEAGVHAACDLVLALRDTGAFAG
VHLVPVSRYRSVAAQLERAL
>A0A3E1BGN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWDAVSKLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGNFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGINEFHLYTMNRAPLVSAVLDNLGFSRRAAKSAGAAA
>A0A080KIJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola SCGC AB-598-I20|TrEMBL
MKTNLLFNQKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHAVKHTYGIESVAHLPGINFDKAEMLKILHDLKCAGIDNVLALRGDINPNVPPKDDF
RFASELVSFIKENGDFNVIGACYPEGHLEASTIKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKAHDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRICEAVSTLLAVPKSA
>A0A4R6DCT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus haemolyticus|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIESYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPE
>U2YGN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus anginosus T5|TrEMBL
MAVLKEMQDLAPHFISVTASNNKFNIEETTVRLADFIRNDLHIPTIAHLPAVYLTKEMVT
ETLTVLDKIGVHKVLALRGDILRDVEPQKDFVYATDLIEYIKKEAPHFEIIGACYPEGHP
DSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYDFQDKCILAGIEVPIHAGIMPILNR
NQALRLLKTCENIYLPRKFCSILDKYEHDPESLRASGLAYAIDQIVDLVTQDVAGVHLYT
MNNSDTAHQIYQATHTFFDK
>A0A502LAS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus haemolyticus|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWNSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIESYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPS
>A0A643FNJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus basilensis|TrEMBL
MQDRYFSFEFFPPKTAEGAEKLRNTRAQLAPLQPKFISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRNILKTYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVAF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRAMGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWVAKRLEGFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNTASATKAIWQRLKL
>A0A844W3G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudooceanicola pacificus|TrEMBL
MTTPAISFEFFPPQSLEASFRLWDTVNVLSPLKPRFVSVTYGAGGTTRDLTRDAVATLHK
NMGLNVAAHLTCVNATKEETMTIADGFAEAGVKELVALRGDPPKGEGQFSVYPGGFANSV
ELIEALAATGKFTIRVGAYPEKHPEAADNAADVAWLKRKIDAGADEALTQFFFETDHFLR
FRDACAKAGIEAPIVPGIFPIGNWKGTRNFAKRCGTDVPAWLDDAFEKAARDGREDLLAT
TLCSEMCTKLMAEGVEHLHFYTLNRPELTRDVCHAIGVTPEVQLENVA
>A0A1R1BN60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus amylolyticus|TrEMBL
MKADLRKAMQERVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFADLGARIIGGCCGTTPDHITAMKEALADYVPLPILEPDPSE
TKARIVLHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDPQLIVAMHEATKHLDVPIFIGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A7Y6AFG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomycetaceae bacterium|TrEMBL
MSVGVASPRNAGGPPGPARAAAIRDLLASGKRTFSFEFFPPKTDTGERHLWDALRRVEAL
GPSFVSVTYGAGGSSRDRTVNITERIATETTLTPVGHFTAVGHSVSELRNIIGQYADAGV
RNVLALRGDPPGDPQGEWIAHPQGFSYAEELVRLLRESGDFCVGVAAFPEMHPRSSNWDD
DIRHFVRKCRAGADYAITQMFFHVDDYLRLRDRVAAAGCDVPIIPEIMPVTNVGQIERFA
QLSNAAFPAALADRVRAVADDPAAVQAIGVEYGTQMGERLLAEGAPGLHFITLNRSTATL
RIYENLGLRDRER
>A0A239K1Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas japonica|TrEMBL
MNPLKQALREQQFVCVMEFVPKPQRLAAFETLMQRGHLCGWPLLAGIADRVGGNLDLSPL
DAYTALSSPVPVMPHFSGKDRERQDLLAQLQRMDALGLEQLLLLTGDRLHGHEPGQRPVR
YLESVAALGIVRQARPHWLLGAALNPFKYREEEGGAQYFKAQKKLAAGADFLILQLGFDM
AKYREAMDWMRHQPTPRPMLACIMGLTHGRAKMLEHVAGVTVSPSIRVLLAAEEAVSKAH
AQARATRRLALQIIGLRLMGYAGINLSGVHEQEQLLALEQALDECHGTIRSEQEWASAWA
ESWRMPDVPAVSFHPPEADWKAGESQVEASTREKLRYHLLSAFHAQLFSRTTLLSRAFGW
AVRRPLWSSPTGARWLHRLERGAKRPLVGCDTCGSCRLEDTLYVCPETCPKGLANGPCGG
TRLNRCEFGDRECIHSFKYRTAKSVGQTTVLTERLIPCVEVGGRHRSSWPRWFPERE
>A0A4V3W964|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allorhizobium terrae|TrEMBL
MADNLQTQALKRPFKLSFEFFPPKSEDMEAQLWETVDDLAGWEPEFVSVTYGAGGTTKAP
TLAVVRRLIAQTPLATASHLTCVGATREEVANVVEEFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGYENAAALVAGLKDLGDFEISVSAYPEKHPESADLAMDIDMLKRKVDNGATRALT
QFFFDNDLFEQYLNRVRAAGITIPIVPGIMPILNLTQLKRFASMCGTSVPAWLDERFSGL
EDRPVVRAQVAAEIAAEQIADLQRRGVDEFHLYTMNRAPLVNATLQQLGLNKPQQQVKTT
APFAESATA
>A0A366R4Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium coffeatum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKSIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFENTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAVYPEWEATGLEAGVRAEAINSRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGNPKTRRDINDLFVKHIQGELSAIPWSE
EELLAESSTIKPHLLELNGKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PSNEWETLRAKLVSSELQDYVCFYASNARGDYVSSDIGGHVNGSTEGNPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNLIHHDY
VNKDALWEVLSS
>A0A5D3G218|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas synxantha|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQSEPSLAVWNNLKLPR
>A0A366RKM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium coffeatum|TrEMBL
MHIKDMLSDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WIAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVADMCRKLLANGIHHLHFYTMNLAQATRMLLEELEWAPSAERP
LQHALPWKQSKGLRRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKTIQDIAQLFVSYLENKVESLPWSEAPLTAEADEIRDGLIE
LNKRGLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPSVFDKMISRIENHP
DLTYYAVTKEGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPI
ANGAVDTEPIANGTTATAVAN
>A0A3G8CIJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. R4-34-07|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYQPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2S7C2K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. corylina|TrEMBL
MDPDTPSLASTITEAYSLEVSAKHIAGLAAAAPRIMRGATIAIPYLPNQDDDARLAAARM
VRTLGFQPMPHLSARRIASREQLHAFVSRAVDDAGVERCLVIAGDPPAPLGPFPDSLSLL
DTGVFERSGIRTIAVAGHPEGHPSMPAADRWEVLQRKCRSIAERGMAPLIVTQFAFDADI
VLRWLQALRAHGIAYPVRVGVPGPAGVAVLARYAASCGVSACASMLSKYGISLGKLLGTA
GPDRFVERLATGLTDAHGEVRMHFYPFGGIAQTVAWVEQYRSRSARV
>F3KU90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hylemonella gracilis ATCC 19624|TrEMBL
MSPQQFPLSIEFFPPKTPEGVEKLRAVRQQLYALKPEFCSVTYGAGGSTQEGTFAAVKEI
LAEGRDAASHISCIGATQATMRENLAALKAMGVKRLVTLRGDLPSGYGAGGEFHYASDLV
AFIRAEMGDHFHIEVAAYPEVHPQARSPEADLQAFVAKVKAGADSAITQYFYNADAYFRF
VEDADALGVTVPIVPGIMPITSSTQLMRFSDACGAEIPRWVRLRLQAYGDDTASIKAFGL
DVVTALCEQLRAGGAPALHFYSMNQSAATLEITQRLGLI
>A0A1S2W0M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. infantis|TrEMBL
MHSPMFSLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGERLVGDFNHASDLV
SYIRSMKPDLTVFGACYPEGHYQSESLDQDIENLKIKVDAGVTRLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLDALLNRWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFLGTQG
>D0W100|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria cinerea ATCC 14685|TrEMBL
MFGATLLCCLKYHIKDNKRYAAMNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETM
LWDSIHRLQTLHPKFVSVTYGANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELR
QIAKDYWDSGIRRVVALRGDEPAGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAK
SAQADLINLKRKIDAGANHVITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQL
GKMAQVTNVKIPKWLSQMYEGLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRS
ELTYAICHILGVRP
>A0A0F6RC95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kangiella geojedonensis|TrEMBL
MSNPVITSNKAKPSYEEARIAEFLNQQIADLDGKVNVSFEFFPPNTPEMQKTLWSSIKKL
EPLSPDFVSVTYGAAASTRSRTHDVITKIIRETELTAVPHLTCIGSTEAEIESIAEDYWS
KGVRHIVALRGDLGQEAEQGDFKYATDLVYKLKQLHDFEISVAAYPEVHPEAETAKADLD
NLKRKVDAGASRAISQFFFSAEKFLRFRDQCQNHDLQIDLTPGILPVTNFTQLQKFAKFT
QVDIPDWMYKVYDGLQNDPETSRLIASHIAIEQVKLLVKEGVSDFHFYTLNRADLTYAIC
HSLGKRCLTPAA
>A0A1E7FKZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fragilariopsis cylindrus CCMP1102|TrEMBL
MSKIIDLIKAKEEGSKPFISIEFFPPRTADGVKNLYARMDRMKESINPLFSDVTWGAGGS
TAELTLDIAEQLSTTGHVANMHMTCTNLEKGGDPKAAVRGALETAKKNGINNIVALRGDP
AAGQEEWKAADGGFTCALDLVEYMTENFGSEFGISVAGYPEGHPNAISEVEDPSSMSEAE
KARSSMEGGKVYTCRDADYKKEMDYLKKKIDAGADFIITQMFFDTKVFGTFVKDCKTWGI
NCPVVPGLMCINAYAGFVKMTGFCKTRVPAELRAKMDSIKDDPDAVKAFGIEFGIQMCQD
LTEIGVEVLHFYTLNLEKTTYGILKGLGYEVKGSAWARVGDQVKTANGVGVVKSIESDGS
ASIEFEGETPTATFKKEEYSKVF
>A0A6I4WWZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus rhodochrous|TrEMBL
MDRLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERLGPAFVSMTYGAGGSTRDRTV
RVTGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWEK
HPEGLEYADELVRLVRDLGDFHVGVASFPEGHHRSPDLDHDTRYLVQKLRAGAEYSITQM
FFDVEHYLRLRDRVVACDAEQGLKPIIPEIMPITSLRSARRSLELSGSHLPPVLEERLRR
AAGDGPEENRAAVREVGIEVATEMCERLISEGAPCLHFITLNFARATGEVLDRLGYELEA
PAVVQPA
>A0A315WR41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SDI|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARTLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRALLAQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIRQESGDHFHIEVAAYPEMHPQARNFEDDLLNFARKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EQVITQMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A850KKL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystaceae bacterium|TrEMBL
MSFEEEREAVLRGLPVAAPLPKDVSVSFEFFPPKTEKMEETLWASLKRLEPLGPKFVSVT
YGAGGTTRERTHNTVVGIQKETTMSAAAHLTCVGSSKAEIQEIADRYWEEGIRHIVALRG
DPEEGAKGYTPHPDGYAYAVDLVEGLKKRHDFEISVAGYPETHPDAPSAQFDIDYLKKKV
DAGADRVITQYFFEAETFLRYRDKAAAAGVNIPIVPGILPVTNFNQVLKFSAACNTKVPA
WMADLFAGLDDEPETRKMVAATVASELCRVLHANGINDFHFYTLNRADLTYAFCHILGVR
PKGLK
>A0A395CTT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystaceae bacterium|TrEMBL
MLDAAQKTSWPPGLFDISYEFFPPKTPEMETQLWESIERLAPLRPRFVSVTYGAGGSTRE
RTHNIVARLVAETDILPAAHLTCVSASRDEVDDIVRGYWSAGVRHIVALRGDPPGGVGSS
FEPHPEGYRTSTELVRGIRRIGDFEISVSTYPEGHPESSSIEDDLDALESKIDAGATRAI
TQFFFENDVYFRFLDKARARGIKIPIVPGIMPVQNFKQTASFARKAGASVPAWLAHRFEG
LDEDPVTRRLIAAAVAAEQVLGLAEAGVREFHFYTNNRADLVFAICHLLGVRPFSEKVAA
>A0A4Q0U840|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Amulumruptor caecigallinarius|TrEMBL
MAQHDILNEITSGHPGFSFEVLPPLKGKSIATLFDNVKRLMPFGPRYVNITTHRSELVYK
SVPGGLYERVSERSRPGTVAVAAAIQNRFNIPAVPHIICSGYSARETEYALIDLSFLGIN
NLLLLRGDKAKHDPRFIPDPAGYAHASELQQQVNTFNDGVMLDGTAFELEEGFKFSYGVA
GYPEKHEESPNTDIDLRWLKHKVDQGASYIVTQLFFDNEKFYRFVEACRNIGIEVPIIPG
IKPIVNLNQLTILPKTFKVDIPDELVAMLDCCSDNVEAKAAGVEWAIRQSQDLIDHGYTH
IHYYSHNAAASVEKIVASVFDRSENIP
>A0A319DFM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus ellipticus CBS 707.79|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMALSKVDDALRAAYKAGCTNILALRGDPPRDKEV
WEATDGGFRYAKDLVHYIRAKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDSDNFIAWVKKCRDKGVNVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLVADMCRKLIASGINHLHFYTMNLAQSTQLVLDDLKLMPSEETP
IQRALPWRPSLGLNRREEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLQDLTHIFVNFLEGKLARLPWSDTPITTEANAIKNSLVE
LNKKALFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLLDELIARIEKNG
DLTYHAVSKHGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDSWYLVNIVNNDFHNSSNLFELFKDMEVKDFDTEIPAENGESK
AHLNGSANGAANGVANGTTPEPAVQN
>A0A1F4NDM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFOXYC12_FULL_65_23|TrEMBL
MGLPLSFEFFPPKTPEGAAKLHAVRQQLYSAKPEFCSVTYGAGGSTQDGTLQTVQAILDE
GQQGASHFTCVGASRESVRDKLALFKSMGLRRLVALRGDLPSGYGGMGEFRYAADLVAFI
RAETGDHFHLEVAAYPETHPQAKSAQADLQAYAAKVKAGASSAITQFFFNTDAYFRFVDD
AYKLGAEVPVVPGIMPITNSAGLLRFADSCGAEIPRWIRLRLQGYGDDVESIKAFGLDVV
TDLCDQLRNAGVPGLHFYTMNQSAPVLEILRRLDLG
>A0A5C1YAF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Protaetiibacter larvae|TrEMBL
MTETVRDGARPTFSFELFPPRDAAAESALVGSTLPALVAAGPEFISVTYGASGSTRDVSL
DVLRRVLETEVRPMAHLTCVGSSYAEASRLIREFLDAGVTSFLALRGDPPAGVAEKDVFL
GDLGSAGELVQLIHRVQAERMPFRQLDVPGVPSAKRLASGEKVTIAVAAFPNGHPRSRSR
AQDLDTLLAKQAAGANLAITQLFFDADDYLGFVDAARAAGVTMRILPGIMPVLSVPRLRR
ILELTGEREPTELLRALEASDDPAAVGIEHATRLASTLLQGGAPGLHLYTFNRHEAPLAV
LAGVGLLPIPEPIGNPLA
>A0A1W1HSP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. ND1|TrEMBL
MSREPRRLKDVLAQGQFSVTVEYNPPKGTNLTHVVESAKALVGRVHGVNVTDNTAAIVRA
GSLPVCRVLYELGHDPVMQLTCRDRNRIAMQSDLMGAHILGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVTGLNNGKDYAGNKLDGSTAFTIGGAVTPEADPLGPMLVKFEVKV
RAGAEFFQTQAIYQPEQFKKFMEAVRPFKVKVLAGILLLRSAKMAEFMNANIPGVCVPQD
MIDEMRAAGDKRALDVGVEIAVRTIKAVRPYCDGVHIMAIKSTERLPEILTKAELG
>A0A1N6MS40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus innexi|TrEMBL
MSFFHANHQEALNQNLAELEGQIRVSFEFFPPKTTEMEQTLWKSIDRLSKLKPNFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDANREELCNIAHDYWSSGIRHIVALRGD
LPNGGSKPAMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATITNVRIPSWMTRMFE
GLDDDSESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A1Q3TJB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. 67-17|TrEMBL
MANTKSSTTTESAKRLVEGYSLEITGKEKDVVGLTEAAPLIPAGTKVNVTFLGNEDLPMR
VAAAKAVKELGFIPVPHISARRIASQAQLEEFLSALAEIGATEHVFAVGGDPATPEGPYP
DALTMIRSGVLQQYGVKEVSIAGYPEGHPDIPTDVLWRHLEDKSAALKDAGLESVILTQF
SFDTDPVMAWIAGVRDRGIDTQIRLGTPGPAGIKRLISFASRFGVGANAMIVKKYGFSLT
NLMGSAGPDKFVSDLAGLFDADPSVGAVKLHMYTFGGLEATATWARDFIAN
>A0A2E8KGK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrionales bacterium|TrEMBL
MISANARSISFEFFPPKTKQGHAKLAETRLALAALEPEYFSVTYGAGGSTRDNTKNVVLD
GLNAGFNTAPHLSFGGDEADTIIALLQEYAAAGVNRLVALRGDLPSGFGGGARLVHANEL
VGFIRQHCGEQFHIAVAAYPEIHPEASSYDTDIGFLKKKFDAGASSAITQYFFNPDAYAY
FIDQCQASGIEQPIYPGIMPITNFDNLLRFSKNCGAEIPRWLCYRAEALQHKPAELNAFY
LEFVSQLCEKLIALGAPGIHFYTMNQAEPSIAICQNLGLQ
>G5C506|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heterocephalus glaber|TrEMBL
MVNEARGSGGSSSGSEGSKDSSRCSTPGLDPERHERLREKMRRRMESGDKWFSLEFFPPR
TSEGAANLISMFDQMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETMLHM
TCCQQSPEAITGHLYKAKQLGIKSILALRGDPIGDQWEAEEGGFDHATDLVKHIRSEFGD
YFDICVAGYPKGHPEAGSFEEDLRHLKEKVSAGADFIISQLFFEANTFFHFVKACDDIGI
TCPILPGIFPIQSYSSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAICNYGIELAVSLSRE
LLVSGLVPGLHFYTLNRKMATTSVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWA
SRPKSYIYRTQDWNEFPNGRWGNSSSPAFGELKNYYLFYLKSKSPRQELLKMWGEELRSE
ESVFEVFAHYISGEPNWHGYKVTCLPWNDEPLAAETSLMKKQLLRVNRLGILTVNSQPNV
NGRPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVMKKYELRVNYHIVDVKGENI
TNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSRMI
IQYIHDNYFLVNLVDNEFPQDSCLWQVGEDAFELLNRPAGLKGEAEAQ
>A0A415BX24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEAQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A415BX24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides vulgatus|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEAQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A1G2K5H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sungbacteria bacterium RIFCSPHIGHO2_01_FULL_47_32|TrEMBL
MRQSGKRPGILKRIARREFLISVQLDPPSPGMFPKFNDSLKKLRRAGVKVFDVNSSRRIC
HDSIQLASELCGTSADVIAHITTRDSSVNGLLNQILAAYEWSDLKNFLVITGDPYESKQA
VFPSRGVFQTDSIGALKAIDWQFRKNLARPLNIVLAAAVNQNEHDRAKEGKRIEEKIAAG
TDIFMSQPVFDSVQADELFKFYGEHSARPLFVGVWPTLNLKTIENIRAGSVEGVRLPRKE
YSELISSFTDENELRRKSAERTIGLVRHIRSSGKATGIYIVAPSRNPLLLLPILKELL
>A0A7E6EP79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Octopus vulgaris|TrEMBL
MFCEKESHVPNSMRRDTEKTDECENLIRYITQKQIEHSIQARRTRYLDALSKTKICSSYE
VSCQKILKMGEINNKQECNGLRKSSMKNNFISLTDQMKLRMSSNDPWFSLEFFPPKTTNG
ARDLFDIMECFAESQPLFCDMTWHLKNDPQNLEKPTSSLCMASTMLNYFNLPTMLHITSG
SQSVSEIKNILNKAKDQGIRNILALRGDKFPGHVASTVDELPYAVDLVRLIRKEHGDHFV
IVVAGYPSGHPECASYEEDLKHLKEKVDAGADFIITQLFFEMDTFEKYVKDCREIGITCP
ILPGILPIQSYLSLRHVSKLTQLSVPEEILNSITPIKDNDEAVRNFGVHHAVELGKKLLN
SGLTKGMHFYTLNQRFATTAILKQLGLLNEEISKPLPWKPSVNYVRLEEEVRPIFWKGRR
KSYICRTADWNKFPNGRWGNSSHASFGNLTDYYMFYLNYSSNEEQLKSLGFQLETEQDVW
NVFYCFIKGHENQNGVKVTHIPWSDDALSPETSLIADQLAYLNKNGVLTINSQPAINGFS
STHPIFGWGNPDGYVYQKAYLEFFTSKENVEVLKKLLVNYPQVNYHIGNSQGDMDYTNCD
ETQPIAVTWGVFPGMEIIQPTVVDPIAFKIWKEEAFSLWKTNWRDLYDPNSKSHKLIDYF
YENYQLVNLVDNNFVQTTCLWEITTKMLSGETN
>A0A1F8KEJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium GWB2_49_20|TrEMBL
MKNYPFLQQLSTRPLLSDGAMGTMLHGRGVSFEQCFDELNLTDPDLIADIHKEYVLAGAD
ILQTNTFGANRFKLARHGLEDRVANINQAGVEQARRAIAASQVDRPILVAGDVGPLGVRI
APYGRVQPEQARQAFSEQITALAAAGVDLLMIETISDLYEIVAAIQAAREVRKRKNAPLP
ICASMTFTRDDRTLLGDDPAKVARSLAEAGADVIGVNCSGGPAQLLRLLKAMRQAVPQAF
LLVQPNAGWPEQMGGRIMYPADPEYFGNYALAFCEAGASIVGGCCGTTPQHITAMRVALD
ENPQGCGSLENVLALPDESGEVPETTPETSRLAQRLSQGKFCIAVEMDPPRGISTHKLVA
GASLLAEAGADVINVADSPMARMRMSAWAVCDVVQRQVGVDSTLHFPTRGRNLLRVQGDL
LAAHALGIRNVFVVMGDPTAIGDYPEAMDNYDLVPSGLIKLIKQGFNTGVDHSGTSIGQP
TAFFVGSALNLNPPEPEKEIKNLHRKVKSGADFFLTQPIYRPEEGPVFLEKYEQEYGKLN
KPILAGILPLVSLKHATFLNNEVPGISIPAEILARLEQAGDQAARVGVETTVELVRQIKT
WAQGIYLMPQFHRYDLVAEIIEAVKEK
>A0A7I6S5K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella sp. WP4-W18-ESBL-05|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A2H0Z369|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium CG08_land_8_20_14_0_20_37_9|TrEMBL
MKVIEHLLKAKEPLISFEIIPPKRGGDIKSLLHVVDDLSKYNPPFIDITSHGAEIVYEET
PQGIKKKIIRKRPGTLGICALIQNKYNIEAVPHILCKNFTREETEDFLIELNYLGIENVL
AIRGDDNGFVKPVPHGRSANEFAVDLVSQVNAMNNGKYLEENLLDAKATDFCVGVSGYPE
KHFESPNLKLDIKYAKQKIDAGAHYIVTQMFFDNNVYFDYVNACKEEGIDAPIIPGLKIL
SLKSHLTNIPRNFYINIPEALAEEVMSAKPEHVLEIGVNWAAKQAEELLNRDVPSLHFYI
LQNSKPINLLMKKLNLHFKKLVVKK
>A0A4P8A936|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum|TrEMBL
MHSPMFTLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPGLKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRAAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNAEPLFLDTQG
>A0A2S5MA70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp|TrEMBL
MKPTAKKFDLSFEFFPPKTTEGMDKLREARAKLAKFNPEFFSVTFGAGGSTRDRTMDTVL
EIQREGYQAAPHISCISSSKSEIRELLQAYQAQGIKRLVTLRGDIPSGEVSAGDFKYASE
LVAFIREETGDHFSIEVAAYPEFHPEARTPAADLLNLKRKVDAGANSAITQYFYNADAYF
RFVDQCDALGINVPIVPGIMPIYNITQLARFSSVCGAEIPRWLKMRLEEYGDDMVSLRAF
GIDVVSELCETLLAWGVPSLHFYTLNQSNIISNIIENVQD
>B0FYT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flammeovirga yaeyamensis|TrEMBL
RGDAAKGEAAFTPHPKGYKYASELVEHVDQLNKGEFMYAESGFKGGFCMGVAGYPEKHMD
ASNLDTDIKYLKQKVDLGAEYIVTQMFFDNQKYFDFVKRCREAGITVPIIPGLKPLTTKR
QLTLLPNIFKLDFPQELIKEAEKCKDNKAIKQLGIEFGIQQAKELMEFGVPSMHYYSMGR
STSVKDIAEAIF
>A0A1G2W415|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadaceae bacterium GWB2_53_15|TrEMBL
MNIIDRLKNEILTGDGAVGTMLYAKGVSLDSNFEHLNLVRPALVRELASEYIAAGAQVIE
TNTFGANYTKLAAIGLGHKVAEINRAGARIARQVAGSGGNILVAGSVGPLLRVKGDEQDL
LAAEVTDIFRVQCHALAEGGVDLLMLETFTSLGQLVAAVRAARETGLPVSASLAFMEGGR
SSDGTTVEAFCVAMEDVGADMIGANCGAGPLELVKVVTRLAALSDKPISAYANSGFPEYR
DGRYIYRATPDYFASMAREMAAAGANLIGGCCGTTPEHIAAIGRVLAGRRPVERTKAVSV
RVAETLDRERPESSSFLDAWGRRKVITVELDPPKGMDCSRIIAGSRCLKEAGADAINLAE
NPLARPRMGNIALGSIIQKEVGIEVIIHITGRDRNLIGMQSDLMGASLLGIRTILAVTGD
PASMGDHAGAKSVFDLHSFTLIKLLADLNSGVNAIANPIGRGTGFTIGAAFNPNTGSMAV
QAERLRKKVANGAVFAQTQPVYDPALFFEALELTRDSGIPLLPGIMPLVSERNAEYLHNE
VPGISIPAAIRSRMKGLEKEAGVREGLAIAKEFIDATIEAAGGYYLIPPFGRYELALELI
DYIHAGERECR
>A0A263NZ19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. IB20|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISQMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1A2DDL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. 852002-51152_SCH6134967|TrEMBL
MEFGPCGGVRPDGQCEMRPGPCTFADVVPWSRPRHEPRPVNPPLVLTDFSNAAFDAQDVA
ATAGLLAPSCDAVLVGEHQNKPDFPPTLMGSLLLDAGVAPWITLSCRDRNRVVLEQELRG
LLSIGVDTALCVTGDGRGYDVRPDVTQTFDLDGPRLVELAASIGMVAAVPETPTAPPVHG
RPARLVEKQRAGASLAVLNHVPFPAMIADFMQSARAAGLSIPVIAAVAVFTDSVSAAVLQ
GLPGLELDPSVTEHVLGAADPVAAGIEAAVAEAEALLSIDGVEGVNVSGLASASGARFGA
EIKAEVGRRIQEVAA
>A0A0C3IEF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. KHS3|TrEMBL
MSSHEHPLGISFEFFPPSTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTREVVR
AVGESGINTAPHLSCIGSEKAQLRDLLAQYREEGVESLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLEGGAPGLHFYTLNQAAPVLRIVDNLAG
>S4H6V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis JCP8070|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNAAGVFNHASDL
VSYIRSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A099ZU24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tinamus guttatus|TrEMBL
MVNENQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDK
WFSLEFFPPRTASGAVNLTSRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPAGEEWQEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAENYEADLRHLKEKVLAGADFIITQLFFRFFFLKF
MKDCQAIGITCPIVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWTEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTSEESVFEVFTCYITGELNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYETRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7Y2XU72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIKRAKGKTLFSFEIIPPVKGRSIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
KDGLYDKKLTRMRPGTVGICASIKHKYDVDTIPHVLCGGFTREETEYLLVDCHYLGIDNI
MALRGDAMKEEQYFEPTEGGHKYASDLVLQIKNLNMGQYLHEVIETDNCSDFCIGVAGYP
EKHMEAPSMKTDLKWLKKKVDLGAQYIVTQMFFDNQKYYDFVMAAREAGIDVPIIPGIKP
IAIKRHLQLLPQVFRIDLPQDLIDEVEKCKSNKEVRKVGIEWAIYQSKELKAAGAPVLHY
YSMGKSDNIREIAKAIF
>A0A7Y2ZQE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHINNAKGKTLFSFEIIPPKKGNSIQELYNNINPLMEFKPPFIDVTTSREQYVYIE
KGEGLLDRKITRMRPGTVGICAALKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMNHQKYFKASKGGHQYAIQLVEQIQNLNQGKYLHDVIEADDKADFCIGVAGY
PEKHIEAPSIQSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFINIARAAGITVPIIPGIK
PIAIKRHLQLLPQVFKIDLPQDLIHAVELCKDNKQVRQVGVEWAIQQSKELQNAGVPVIH
FYSMGKSDNIKAIAKELF
>A0A7Y3PI06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MAATRENHLEEVLRAGQFAVTAELSPPDSADPRGALRKASVLSEMVDAINITDGSGANCH
ISSMSVAALLVNEGITPVMQVTCRDRNRIAIQGDILGAAALGISNLLCLTGDAIGSGDHP
DAVAVCDLDSISLLDTARTMRDEGRFLSGRMLTSRPNLFLGAAANPFSPPYQIRALHLAK
KVSAGAQFIQTQYCFDLPMLERFMGQIRELELDQRCFILVGVGPLPSARTARWMRASVPG
IHIPDQVIDRLERAKDPKREGRQMCIELIQQICEVEGIAGIHVMAHRNEELIADVIRESA
VRGLQRKVSPGTKFAGETKS
>A0A7Z9ZYB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MSRLKEAFDSGRFAITSEIGPPKGTNVEKVLEEAERYLKGRVDAINVTDLQSSVMRLGSL
VTCYLLKQRGMEPVLQVTCRDRNRLALQSELLNAAVLGIENVLCLTGDHVSLGDHPEAKP
VFDLDSVQLLRAAKGLMEGRDLAGNELDGTPNFFLGAVVNPGYEPLDLQLLKMEKKIEAG
AQFFQTQTVYDPKVFERFMRRAERFGVPVMVGIVFLKSPAMARYMNENVAGVRVPDEIIK
ELASVSKEDRPKKSVEITARLIREMKDMCQGVHLMPMGWDRYVPDVLEAAGL
>A0A7S1CN74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bicosoecida sp. CB-2014|TrEMBL
VDAGADFIITQFFYDPDVFLRFQEECVDLGITVPILPGYMVVQNYNGYKKFTDWCRTTVP
EGMRADLAAIKDNDEAVKAYGVKAGAETCRYLLSKGSKFLHFYTLNLSLSVTKILETLGL
VAKRHERPLPWMPAATGEARAKEEVRPIFWAHRAASYLSRTAEWDEYPNGRWGDARSPAY
GEISEYYLGLKRPKVRRHEQWGVPRSPADVGAVFSKYISGDVDQLPWSETPLALESGQIK
ENLTWLNEHGFLTINSQPKVNCVPSNDVRVGWGGDGGYVFQKAYVEFFVSPDLFSRLLGL
LKTEAYAHLTYHAVKVDGEEETNADREHATAVTWGVFPGREVIQPTVVDPRSFLAWKDEA
FDLWLSQWASAYDEEREDEATARAVIEDIYESWWLVNVVDNAYAEPGSDIFGVFREAITD
AMGEEELRTYARRLQEDNVRLTEQLERMRDLQAAHAAETARYADALARSEADNMQLRTQL
RAAQAKAVMTPTERGVRSSAVSANGGAGGATAPGVGLPPRKPLVARKTPA
>A0A7Y1TM53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIKKAKGKTLFSFEILPPLKGQHIQSIFDTIDPLMEFKPPFIDVTYHREEYTYKE
LENGLLKKQVVKKRPGTVGICAAIQNRYQVDAIPHILCGGFTKEDTENFLIDLDFLGIHN
VMALRGDAVKSETYFRPEKEGHKYACELVSQIQELNRGNYLDDELQNTSKTDFCIGVAGY
PEKHLEAPSFDSDIHFLKKKIKKGADYIVTQMFFDNTKYFQFVDKCRSEGITVPIIPGLK
PIATKNHLNLIPHRFSANLPDELIMAIVKCRDNAEVRQVGVEWCIKQSKELMKAGVPLVH
YYSMGKSTNIKAIAQAVF
>A0A849IUQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MVAGEAPMGALFSNARIEVIPTKSVGDQVEQLISKDVTIAVTASPVKGLDSTFELAERLC
DAGFNVVPHLSARLVVDEKHLAEIVARLTERKISDVFVPAGDADPPAGKFDSSLSLLEAL
DQMGRPFDRVGITGYPESHPKISDDVTVQAMWDKRHYASYVISNLCFDPTIIRHWVERVR
KRGVKLPIYLGVAAPIDRTKLLDVASKIGVGESTKFLTKHAAWFLRMGTPGGYSPNRLLQ
RIGSTLTTESSLIEGLHIYSFNQIRQSEEWRVGQLEKFGGTIHEKALQSHPAN
>A0A853AT72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora hordei|TrEMBL
MAHLTAVDHSVAELRHAVGWYAASGVRNVLAVRGDPPGDPTGPWVRHPEGLEHAEELVRL
VRELGDFCVGVAAFPHGHPRSTDLETDADHLVRKVRAGADFAIAQLFLEPEHFLRLRDRM
AARGCHVPLLPGVMPITTPRVLAKFGELAGVPVPRAIADRLLPLVDDPAGFRQAGVDVVT
RLCERLIAEGVPALHFYTLNRSKATRQVVASLGL
>A0A7S0PJ14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cafeteria roenbergensis|TrEMBL
QESRHPKMAARIDELMAAHSGDAPWVAFEYYPPRTEDGVNNLKKKMPRFKAQKPLYIDMT
FGAGGSTSDLTLDLCKEAKAAGLEPNMHLTCTNMPQEKIYEALEGAKAAGIRNIVALRGD
PPLGQERWEAVEGGFTCALDLTKHIVKTYGKDQFCISTAGYPEGHPGAIKKVAEGQELSD
KEKRRVVSLEDGDYVCSDADFAKEMEYLKAKVDAGASLIITQMFFDVDVFADFLEACKEY
GITVPVIPGLMLVQNAGGFGRMTAFCKTRVPASIREGLEAVKEDDAAVKQFGIDLGAKMC
EQLMALGCKGLHFYTLNLEKVTFGVMRKLGLFDEDAAAAAAAAAEPAAAASAGAASA
>C2YWJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus AH1271|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVIRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7K1YTX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MLSKLRRAPLSGETLGARHYRLHLVRDLTFEVIPLKSLDAAIEALPAGSRVSVTASPVKG
QDATCEITERLMELGHEAIPHVSARMVTDRARVSELASWFRSAGVSTMFLVGGDVESPGA
YSDAASFLRDLLECDHGLSTIGVTAYPHGHPLIAEEVLHEALHTKQALLAEAGVEGYCST
QMCFDPARIEGWLRGERAAGLTLPVHLGISGVVDRAKLLTMGARLGVGPSLRYLRKNRAA
IMKLMTSPNYDPDHILMALSPSLDDLGVTGLHVFTFNQVATTVTWQSSHHG
>A0A1M3BPF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp. 65-6|TrEMBL
MKPATAIPARKDIRLSFEFFPPKTAEAEGQLWETAAELSAYAPRFMSVTYGAGGSTKAPT
LATVRQLLKMGLPAASHLTCVGATREEVHAVVAEFQAVGVKHFVALRGDPPGGVGAPYQP
HPGGYANAAELVAGLRGIADFEISVSAYPEKHPQSPDVAADIDMLKRKVDAGATRALTQF
FFENDDFERYLERVRKAGIAIPVLPGILPVHNLAQVRKFAGLCGATVPGWLADRLGPIDD
RPQERAAVAVELAIRQVEDLIARGIGEFHFYTMNRASLVSQVCDGVGFAKIDRSRAAGAA
A
>A0A372UMC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AM23-12|TrEMBL
MRVIDLIHNSEKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLFWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEALKCKNDKEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A351KAB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSTRNKADRAVQKRLLEGMTYELIPLKNLADQSMFLPAGSTVSVTCSPAKTVDDTLDLCA
HYGGQGFTVIPHLAARMVEDEEHVERIARRINELGIRTVFCIGGDAEPRGPFTDTAGFLR
SFLDRRPEIDTVGVGSYPDGHATIPDQALVDGLVEKQEMIREAGLGGYMATQMCFDATTI
ADWLKGRRDAGVDLPCHLGVPGAIDRTRLLTISIRLGIGHSARYLKKNSASVIRLLSPGG
YNPSKLIDPLSGVAEELDIVGIHCFTFNAVDTTEDWRQKALQKLG
>A0A2W4VDR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTQHIENANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPSGLLQKKIVKKRPGTVGICAGIQNKYDVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKNETYFRPEREGNEYATDLVLQIDNLNKGIYLDEDLQNSAKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNKKFFDYVAKVRAAGITVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMAVVKAKDNDAVKQIGIEWCTQQSKELVAAGIPVLH
YYSMGKAENIKAIAKEVF
>A0A381A8I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira pilosicoli|TrEMBL
MNNNVENFIKKLENNNEYCFTLEISPQAKYDLSYNNSQIQNYADAFVVTDSPFANIKISP
ILAAIQLQQRLNNNKPFIATQTMRDKNSLALQNDLIGANYFDIRMILAVTGDAIANGNQK
QAKGVFEGNSNLLIDIIKNLNKSKSLGEFTFKEPLKPIYPFCVINSYAKNDDSLKVRLAK
KANSGVKAIFTQPIYEVERLEFLLKCIDELPLKEKPILVPGFFPVLTYKTAYFIYYKLSG
SYIPEKWLSKLKKASDKSEEEERKTAIELSSKLFEDMLKIHKKMHIMSLNNYEFVVDLLK
NI
>R9N2H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 10-1|TrEMBL
MKVSKIVQAKREEGKPVLSFEIFPPKKEEALKNIDATLEKLCDLHPDFISITFGAGGSAV
DNQTVELAKKIKNNYGVEPIVHLTCLHYGKEEIGMILSQLKEEGIENILALRGDVNPNIP
VKNDFKYANELVAYIKTQGDFHISGACYPETHLEAKSAIDDIHNLKKKVDAGAEHLVSQL
FFDNEAFYQFYEKTRIAGIKTPVEAGIMPVTNRAQIERMVNICGAAMPAKLEKILHKYEH
NKEALFDAGLAYAVNQIVDLIANDVDGIHVFTMNNSKVAGRICDSIRNLI
>A0A1M3BRQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp. 65-6|TrEMBL
MAHIDENPLGAHLPLDPLPGHASLGRLERVLRRGEFAVTTELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNSKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPFRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGV
GPMASAKTAKWIRSNVPGIHIPDAIIRRLEGAEDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRRPWKREPNPVDQLVAERIEMARSGQEQDQQQMAEKAA
QHPH
>A0A2E1JDS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MKKISRQVSEIHTEFSFELFPPKSEIGEKNLLSQIHLVERIKTRAICVTSGAGGSGNDRT
LKTIKSLENNVSSNLTAHLTCIAATKNQTHQSLDRYAQEGIFNIVALRGDLNEDQNDLTT
LDSYGNAANLVRGIRNRNDGDQFHISVAGYPETHPKAKSRKSDLENLKEKVDEGADLILT
QFFFDPVTFFQFIEDTDRVGISVPIIPGLVIPSNFHRVFNFAEKCGTHIPDSLVKKFDGV
ESGSETANRIATEITLQQCSHLSENDIRSFHFYTLNRLDLVVPVCELLQEGISSSPKPVH
RKP
>A0A2E8LJP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
HVACKEGKLVDWQRLKAKIDHGADFVLTQLFFDNDDYFAFRDYLVGELGVEVPLTPGVLP
ILSTPQITRFAAICGATLPASLRSRLEALGDDQAAVADFGVEFASRQCEALLAGGAPGVH
LYSLNKAEAATAIFTHLGLAGQA
>Q01QP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solibacter usitatus (strain Ellin6076)|TrEMBL
MNTTTSSRAQEFRDQLARRVIVADGAMGTMLYSRGVFINRCFDELNLSAADMVRQIHQEY
VKAGAEILETNTFGATRQRLGAFGFAEKLQAINHAGVRLAREAANGSAYVAGAVGPLNVR
IEPLGPTSFAEARAAFREQIDALLEAGVDLLIFETFGNLDELREAVYAGYDASRGEVPMI
AQVTIDDFGHLPGGTDTETFTREMNNWPVDVIGLNCSVGPKATLETVERMMEFATKPLSA
MPNAGLPMRVEGRNIYLCSPEYMSQYARRLLWAGVKVIGGCCGTTPDHIKLIRSETRSLQ
PLQKQLAVTVEEPKVKAQALQPVPVAEKSQVGAKLAAGKFVTFVEILPPRGVDATREIAG
AKLCAEHGIDAINVPDGPRASARMSAQVTCQLIQAQAGIEAVNHFCCRDRNILGIQSELL
GTHGAGVRNLICITGDPPRMGAYPDATAVFDVDAIGLVNIVRNLNHGLDIGGNPMGSQTA
LLIGVGANPGALNMDEEIRRFEWKVEAGAEYVVTQPVFDLDLLEAFLKRIEHVKIPVLCG
IWPLTSYRNAEFMVNELRVPVPEMFMERMRRVDNAEKAREEGVAIAREMVARVSKMVQGA
QLSAPFGRYQMAIDVADAIESR
>A0A2S0JEZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter fetus subsp. testudinum|TrEMBL
MLKKKIKDNTPGILLYGLTPPKLNLTHEEAMVVAKKQLERLENRGIDGLVIYDLQDESNR
NESERTFEFCGTIKPEIYHKEFLKSAYPAVIYKAVGNYTQDEFCRFLNDSGENLSVFVGT
SSKKDSPKLSLDMAYKLKKEQGRDITLGGICIPERHEKKGDEDLRVAGKTIKGCEFFITQ
AVYNLEHAKRFLDDYSNLNIKKVPIIFTFTPCGSLKTLEFMRWLGISVPKQFENRLFESD
DPLKASVNLSLDMFEFLYKYGRAKGISVGANVESISTRKVEIEASVELVSGIKSIIS
>A0A7K2PBF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5926|TrEMBL
MAHSADPELSVDELVRNSSIEIVPLKGAQEKVDAVPAGTTVSVTCSPRFGLARTLDHVAA
ARRSGHRVVPHLAARMVEDRAALRDFVRGVADLGVEELFVIGGDGEKPVGRFSEAAEILE
ELVEFDHGLSRIGVGCYPEGHPKIADDVLFEALLRKQQHADYMVSQLCFDASALAGWLRS
ARERGVTLPLRMGVAAPLQIRKLIELSVKIGVGQSLRFLSKQHGMVGNLLLGRAYEPLDL
LLAVREEISFTDLSVEGLHLFSFNQVDTTLDWLYRASGVEKAG
>A0A6G0KR90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora fragariae|TrEMBL
MSTPTSPALASKGESEQQLHTQAAISGEELYLQELTEALVVPAVQITTRSLENSSSPVPS
TSSEDECSPDPESPVEHAEEELERGEIHDNRDPSNDTELVDDGEPTTDVVVKFSGVHKAE
ATEAQADETPAPPLQPPVVEISTSRTSQLPGEGQRCNRHMDPPQTLDTCDSRLLPNDSLA
TSVSAFIKWEEAAALEAFPLAVVPSNHPHTREKGSKMPRVSSIHVTKQKERHEEADELAA
TKFVLDDSTVWTGLSTEDVNEALTLHGKALAMAKLMNCRRERLERVKATRRGCCSGCTWC
RVQNEFQLDVLLHLTCHLPTEQLKRALGLQRLKAKQDAGADFIITQFFFDVDNMIHWIAD
CKDAGITILPGYLSIQNYSSLCKFTSWCKTRVPESVLAALDTIKNDDAAVRRYGTQLAAE
TCQRLLAAGVNSLHFYTMNLPRP
>A0A0J5GSC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. LL01|TrEMBL
MGILDSLQQDKILIADGAMGTLLYSFGSDCCFEELNLSHPSQIYNIHKAYLNAGANLIQT
NTYAANYHKLERYGLQDQVKEINSAAVRLAKKAVADHPDAHVVGTIGGIRAIKPEAIPLE
EIKRTFREQLYCLLLEGVDGILLETFYDLEELETVLQIARKETNLPIIAQVSLQEVGHLQ
NRVHITDALNRLESLGADIVGLNCRLGPYHMISTLEEVSIPKHAYLSAYPNSSLPSYVDG
KLEYESDAEYFKETALAFRDQGVRLLGGCCGTTPAHIQAFSEALRDVAPLKEKQVKRKER
KIIIPSQKKNVPTPIFEKAKKEQSIIVELDPPRKLNTEKFMSGAQALKDAGIDALTLADN
SLASPRVCNTALGSIVKSDIGLRPLIHITCRDRNLIGLQSHLMGLHQLGIHDVLAVTGDP
TKVGDFPGASSVYDVTSFGLINMIKQFNQGVSLSGKELGEQTNFSVGAAFNPNVRVIDKA
VERLEKKIEAGADYFISQPVFSEEKLLEVYHATKHIDAPIYIGIMPLISSRNANFLHHEV
PGIKLTPQVLEAMNRHQNDPQQASLEGLNIAKGLLDVALELFNGIYLITPFMRYELTVEL
ATYAKKYGPFHSSRRVQNV
>A0A8J5D7J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nymphon striatum|TrEMBL
MRGSVLSRTQGAASERNIRVSFEFFPPKNDAMEQTLADTITKLAPLSPDFISVTYGAGGS
TRDPSKRTLAKVLEQTGVPAAAHLTCVGSTKAEVDEVVRDFASMGINRFVALRGDPETGM
GTQYVPPVDGYETSADLVAGLKAYADFDVSVSAYPEKHPESPDFATDIDMLKRKIDNGAC
RAITQFFFDNDSYERYVERVRRAGIYVPIVPGIIPIHNFWSVANFAGRCQTHVPSWLEER
FAGLEKDPQTHALIASAIAAEQVMDLVDRGVEDFHFYTMNRPDLVFAICRLIGIKGDDDN
GVIAA
>A0A150PYS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
MSRTRPEAPLLEALQRSILVFDGAMGSLLYERGVFVTQNFEQLNVTRPDLVKKVHADYVA
AGANVIETNTFGANRFRLERYGLVNEVRNFNLAGARIAREIAGGDAYVAGSIGPTGLVPG
VATRDDLAAAAETFAEQAGALAEGGVDVLVLETFRHLDEIKLAVEAARKAAPGLPVLASM
TFDTSGVVADGSEPERVARTLRDWGVDLLGVNCGDGPQLSLAMAERMATAGLPLCVQPNA
GLPRTVDGRLLYMATPEYFDVFARRMIQAGAAMIGGCCGTTPEHVKWMAKSARMLRGGAA
PEVAARPHITMDAPTGSEPTPLGERSPLAAKLAAGKFVVSVEVNPAPGLNPDSALSAAKM
LIDSGVDVVNVADGPRATARMTNLAFCALLLQRYGIEPILHVCGRDRNLIGQMAHLLGAH
AIGIKNLVVITGDPPKVGDYPEATAVYDLDSIGLLHMASTMNRGLDPAGKPIPGGKTSFL
LATGLEPGAPDLDKEIARLERKRAAGADIIMTQPVFHQDLLAKVLKRIEHLGMPVLVGVL
PLVSYKNAEFLHNEVPGMQIPDEIRERMRKVPAGPEARKEGVKIAREMLFSVRDRVQGAY
LMPPLGKYELALEVLDGLKKG
>A0A7Y9ZK45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides aromaticivorans|TrEMBL
MTTGAGRSLGELIREGGRSFSFEFFPPKDEAGEAQLWDAIRALEPYQPTFVSVTYGAGGS
TRDKTVAITGRIARETSLIPLAHLTCVGHTREELEGILDAYDAEGVAHVLALRGDPHEGP
RADWTPTEGGLNYAIELVELARARGSFRVGVAAFPEGHPSAESLDHDADVLVAKARAGAE
FAVTQMFFRASDYFGLVERVRERGVDIPILPGIMPILNLSAIRRQGELIGTSVPDEIVER
ISAYDGDPAAVRAEGIRIAAELCDELLAGGAPGLHFYTLNRSKATLEIFEALQITV
>A0A0M4KGY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALQNMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIKFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A150RG26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
MVSKSKMESLLSERRFLVSAELTPPRHHDLEKLLRHARSMADCVDVVQINDHLLSQARCA
NMAVGHFVKQEGLEPVLQFSLRHKNRIALQGDLLGMAALGLSNIIILGGYPCAIGSDPDA
KEVSDVDSYAAIELTRRLTREGKLFNGDVISPAPYFHVGTIDFPCAEQAIAGAMDRLSAK
IDAGASFIQVQAVFELASMRRWMAAVVERGLHERAHFIAAIFPFAGVDRLNFLQKVPGLV
VPDHLIERVRQSGDAEGESYRITLELVRGLRGIPGLSGIHMRSIGAEDWVPRLVEDAGLR
RAA
>A0A170PTH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MSSLATPRQAGSPSVSFEFFPPKSEAMADRLWETVERLEPMTPNFVSVTYGAGGSTRERT
HDTVRRIAQQTHLRPAGHLTCVSATKDEVLSVAEDYWEAGVRHIVALRGDPPSGMGEKFE
QHPGGFRDSIDLIEGIRAHRPDLGRCFEISVSCYPELHPESQGWDAEIAFLKAKQDAGAD
RAITQFFFEPEIYLNFLEKARAGGVTMPIVPGIMLQPNFKGLKRISKLCGASLPTWLHEL
YEGLEEDQETRELVTANVAADLCRKLSDEGVSDFHFYTLNRAGLALSTCRLLGLKPKPVE
AA
>B0TCJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heliobacterium modesticaldum (strain ATCC 51547 / Ice1)|TrEMBL
MMRIYGGLPMTGITVELVPRSEEALISELEMIQQEFPQVMGINIPDLLRFPLRSWDACTC
AKRYFATAIPHIRAIDLNPDAPLQMAEQLQQNGIAEVLIVTGDPPQDMSRKVYPTTSIDV
IRRFKRELPDMKVYAAIDPYRNSLRKEYDYIKRKIDAGADGFFTQPFFDLRFMEIYGEML
EGQQVFWGISPVTTEKSACYWETKNHVLFPADFEPTLEWNIRFARKVLDFVAQSKANMYF
MPIRTDLRAYLRGIFCNP
>A0A3B0YM84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MESQKKHHRVYSFELFPPKTDEGAAKLRVTRDELAKLKPRFFSVTFGAGGSTRERTFDTV
HEIQQDSGIEAAPHLSCVGSTKESIREILDLYRNENIHHIVALRGDLPSGMGQPGEFRYA
NELVEFIRAETGDHFHIEVAAYPEFHPQAQNAQTDVDNFKRKVDAGADSAITQYFYNADA
YFGFVDLCEKRGIDIPIVPGIMPITNYTQLARFSDMCGAEIPRWIRKRLEACGDDRDAIR
TFGAEFITTMCRQLLDAGAPGLHFYTMNQAGPTRAIWEQLDLD
>A0A077L0Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter guillouiae|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKLVHQELQLLNPEFFSITYGAGGSTRERTLAAIADFN
GKGTPVAPHLSCIGDDKVRIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADNFDADIKHFAEKVKAGANAAITQFFFNPDAYFYFV
ERIQKQGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVIKLCERLIAGGAPSLHFYSMNHTEPNRQLVLDLGLA
>A0A1L3RV02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulibacter bethesdensis|TrEMBL
MNRLAGQEQQGESATLRRWLTGPRVTGLPAMDAEHPVPLLSFEFFPPKTEALERQLWSCI
RRLEPLGPRFVSVTYGAGGSTQARTHETVARIVRETSLTPAAHLTCVGATRDEVDEVARH
YWEAGVRHIVALRGDMPGGAPYQPHPGGYAYASDLVAGLKRIGDFEISVAAYPETHPAAP
DAGFDLDNLKRKLDAGATRAITQYFFDTDTFLRFLDRCLVAGITAPIVPGIMPVSNYAQA
VRFSTAIGTSVPDWLGRLFDGLEDDVETRRMVAAVVAAEQVRLLQANGIDEFHFYTLNRP
DLVYAIARILGVHPAVAPVPEQV
>A0A290RWJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas agarivorans DSM 14585|TrEMBL
MALSLQEKIEDTNQGVYLIGTTPPKIGTDKAQLKIIAEKLLARLHEIEYDGVIIYDIQDE
SSRTDKARPFPFKQTVDPREYSHLLRNLSAPDVITYKSVAQRGVEEFKGWLDETKNDYDL
KNVVLVGSPSSVGDIKLSLPDAYKTLAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGITPKRIILTFTPCGGDKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKQIA
>A0A4V3FPI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. CC22-02|TrEMBL
MSARAPAQAAAFIYRYSLEVSAKALPALRAEADRIAPGTIISIPYLASEDDNTRLAAARA
VRELGLEPMPHLSARRIESRAALERFMQRAASEAGVERCLLIAGDLAAPAGPFADSAAII
DTGILEGSGIKVVAIGGHPEGHPVMGSGESWQVLERKCQAIEGRRMAPLIITQFAFDADI
VLAWLDALRSRDIRVPVLVGVPGPASITRLARYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVRGLTDAHGAVSPHFFPFGGIAASLAWIERYRRHALASSPS
>A0A4R5F9L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium rhamnosiphilum|TrEMBL
MKVTQHIEDAKEKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYID
KGNGLLDKRLTRMRPGTLGICASIKHKYNVDTIPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQYFIPKQGGNDFAVDLVKQIYQLNNGKYLHDVMEVDNKSNFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIHAVDQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A1Q9MXL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lokiarchaeota archaeon (strain CR_4)|TrEMBL
MAQKPAYSELMRNIYAGKFVFTGEIEPLKTANMTPYIKEGKLLKDAGCVAGNVTHNPKAD
ATVSSMAASYTIQKESGLECVYQLTCRDMNRMALISDILGAAHLGLHNCLALTGDHPSVG
DTPESKPVFDLDGQQLAMLVREIVDKHTAFGKPLKEKLGQFPQMHVGCAGNPNGKDDGFW
AEIMKIQRKTGIAEFCQTQVAFNIDQSIAWCKEVAKSKIPILIGIFPMKNFPTAKGFNDF
VPGVNIPQAVLDDFKAVHKSNMSEEEKAKTYEKKNVDFWVPFLKELRSKNLVAGAHVMAV
QYASCVGAITREMAK
>F4S8A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7)|TrEMBL
MKRIDELIKSLNESNQVYFTFEFFPPKTIDGLQNLQTRIQRMIKLNPSMIHFTWGPNGST
FKTSLGLVSFVQIELGFPTCLHLTCTNLSIDLLNQALNEAKKLGIVNILALRGDPPRPNE
YTTDPTTTTTTTTEFNHAIDLVKYINLNYPKTFCLGVAGYPEGSSEYDSNQELNFLKEKV
NAGAEFIVSQLFYDTQTFLDWYHDCRRVGNVPIIPSIMPIQSYESFRRLTALTKIKVPQT
ILDSLSPIQTNDQAVKDFGLKLSLETIRTLRSHHINSFHLCTLNLEVTITRLLSSLNWTT
PSMSSTTTTTLLLPPNDSRILPIVQPGLEPNTWDEFPNGRFGDSRSPAYGKIDQYYGGIG
KLSCDSLTGLKQWGSPKSEAEITDLFVRYTKREIDSTPWSDTPLLEESDLISDTILKMNM
KGYWTISSQPACDGFPSDNQFVGFGPKGGYIYQKSFVEFFLNQTQLEILLMAIEMENSKA
EVGMLKYFAGKRNSDEIKSNVNVGETNVVTWGVFRSAEVVTTTIIELNSFKTWKDEAFEI
WSSWESLFHHQTDHQTKTLINSIGNEKWLCTIIDHDFKLEEKLWKFLEFNCI
>A0A0Q7F9G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium sp. Root1290|TrEMBL
MSPHETALGPVARAAAGNTRRPSVSFEFSPPKTPEAEVSLWEAIRRLEPLNPSFVSVTYG
AGGSTRDRTHRTVVRMLKETTLKPAAHLTCVEASKAEVDEVVQAYWDAGIRHIVALRGDP
PGNIGGVYAPRADGYLNATELTAGIKAVAPFEVSVSLYPQIHPESPSIDHDIEVLKAKID
AGATRAITQFFYDIDAYLFFMDKLRKAGVTIPVSPGIMPVSNYKGLKKMAGPVGIPLPAW
LGNLFDGLDKDPETRKLIAASVASEMCVRLAEEGYSDFHFYTLNRADLVYAICRVLGVRE
APTEPSEVAA
>A0A238J5W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boseongicola aestuarii|TrEMBL
MTRPTISFEFFPPQSLEASFRLWDTVNTLSHLDPAFVSVTYGAGGTTRKLTHEAVDTLGR
HMGLDVAAHLTCVDATREETLEIAANYAKSGVNRIVALRGDPPKGAHAFTPHPEGFADAT
ELVAALAETGQFEITVGAYPDAHPEAAYPGADIDWLKRKIDAGATNAITQFFFEAETFLR
FRDRCADAGITAEIIPGILPIENWKGTERFAKRCGAHIPPTFASMFETAERDGRSDLLST
AICTELCTELLEEGANHLHFYTLNKPGLTRDVVHALGLAPHISLEKVA
>A0A3S2TN55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rheinheimera sp. YQF-1|TrEMBL
MSFVSAQYVESMNRNLQDVAGKVNVSFEFFPPKTEQMENTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASRAELERIAKDYWDNGIRHIVALRGD
LPPGNKEKPALYAADLVEILRSVADFDISVAAYPEVHPESPNAQFDLLNLKRKVDAGASR
AITQFFFEPEKYLRYRDRCAAIGIDVEIVPGILPVTNFQQLTKFATMTNVAIPGWMNKAY
EGLEQDATTRNLVAANIAMEMVKVLSREGVNHFHFYTLNRCELSYAICHLLGVRPQSAIA
>A0A0A8DVU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sacchari|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTATRLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
RFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQAHDALSDLRHFKAKVDAGADAAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAEAIREFGADVV
ATLCQRLVDGGAPGLHFYTLNLAKPTTNVLARLRGDVAAG
>A0A373N4T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. AF32-4BH|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A7W9FDS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas variabilis|TrEMBL
MTAEIVYSAAPAQGPGPAATLAEARALLLSPLGPVARAGENANPVQVSFEFFPPKTDEAE
ANLWKAVRRLEPLNPAFVSVTYGAGGSTRERTHRTVQRMLAETTLKPAAHLTCVEASRDE
VDQVIADYKSIGVDHIVALRGDPPGGAGIGGAYRPREDGYANATELAQAIQRIGGFQTTV
GVYPEKHPESPSIEHDIDVLKAKVDAGATRALSQFFFDIDAFLRFRDRIQAAGVTIPLIP
GIMPVSNFGGLQRMSAACGASVPAWLASHFDGLDDDPETRKLLAASVAAETCARLQEEGF
SDFHFYTLNRADLVYAICRVLGVREQKVAA
>A0A6H1RHF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora sp. ASAGF58|TrEMBL
MTAVVDRLNTEKTTFSVEFFPPRSDDEERILWRAVRELEPLDPAFVSVTYGAGGSSRDRT
IRTTGRIAQETTLTPMAHLTAVDHSVAELRNVIGWYAASGVQNVLAVRGDPQGDPNGEWR
QHPEGLTYAEELVRLVRELGEFCVGVAAFPHGHPRSTDLDVDADHLVRKIRAGAGFAIAQ
LFLEPEYFLRLRDRMVARGCDVPLLPGVMPITTPRVLGKFGELAGVPVPAEVSEQLWPLA
EDPAGFRAAGVDLVTRLCERLIAEGVPALHFYTLNRSKATRQVVANLGL
>A0A8F2F2J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Christensenella sp. MSJ-20|TrEMBL
MSIPALFQKGRVLSLEVFPPKPDAPIEVIDGTLNLLAPIKPDYISVTYGAGGSGRSRSVE
IAKKILPICDCLSHLTCVGADAQEIDNVLDSLTAAGVENIMALRGDVPKDMDRESAFVHF
KHASDLIEHIKDRGGFHVAAACYPEGHPQSDYLEQDVDMVKRKVDAGAELLVTQLFFDNV
LFYRFMELLRKRGVTVPVTAGVMPVLNAAQIVRMTLLSGTSVPPDLAKLIARYGDNKEDF
KKAGLEFAMNQVSGLMANGVQGIHLYTMNKAEEIIQIIRETGLRSH
>A4J5C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforamulus reducens (strain ATCC BAA-1160 / DSM 100696 / MI-1)|TrEMBL
MIREYLKNNILITDGAMGTYYAQITGKYNVFPEFANINEPEIIERIHTEYINAGAKLIKT
NTFSANSRVLKIPKSEVKKIVLAGLDLANKVAQGKSIFIAASIGPIPEMFDKMETDQENS
LDEYKFIVDIFLNSDIKIFMFETFSDVSDLLEITKYIKVKDSSAFIVTQFATTPEGFTRK
GLSNKHIIAEVKKSKSIDAYGFNCGVGPTHLFNSLKKLNFADDMVAAAPNAGYPEIVHER
MVYIQNPNYFAEKMKDISGLGVKILGGCCGTTPIHIEKMSELIQSYLNAPIPKQQISAKP
KVIIDREKTDGFFEKMRKGKFVIAVELDPPFNADTDLILQNAWICKDHGVDAITIADSPM
ARARADSIMIAAKIKREVGIEVLPHLCCRDKNLNALKSALLAGYIENIRNVLAITGDPVA
IADKNDIKGVFNLNSMKLIQLISTMNKELFPEDPINVGGALNLNLLKPEAELAKMVKKIN
SGATFFLTQPIFEDYVINILRLINKNDGIKILGGIMPLVSYKNALFLNNEVAGIKIPERI
INKYNSNMGKDEAEIIGIEIAVEIANKIKESVDGFYFITPFNRVEMIMKIIKKLKCFH
>A0A8H4ZD35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium austroamericanum|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WEAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPSADRP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKAIQDIAELFVSYLNNKIESLPWSESPLTTEADEIRDDLIE
LNKRGLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPA
ANGAVDTEPIANGTAVTAAAN
>A0A2H5ZWL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR32|TrEMBL
MNPFLERLQRGVLVADGAMGTMLYARGVPFDQPFELLNVTNRDLVVAVHVEYLRSGAELI
ETNTFGGNRFKLGAKGLADRVRELNRAGAKLAKEARDVAGVPVFIAGSVGPLGKPLKPFG
LVTPEEAYQAFREQVEALVEGGVDLLLLETFSDLDELGVAVRAARDCTDLPVVAEVTFDE
EGRTLRGHVPAEVVQSLEPLGVAAVGANCSVGPLPMVDVVAAMVQVASVPVTAMPNAGYP
ARVEGRYVYSTPPRYFAEHARRMAELGARVVGGCCGTTPEHIAAVAEAVRGLRPAPEPRV
VVTLPRKPEPPRPPEEATELNRKLGRQFVISVEVDPPKGTGPTKDLLGARLVKERGADAV
NVGDSPLGRVRMSASALCVLIQQHVGIETIIHFTTRDRNLMALQADLIGLHALGVRNVLA
LTGDPPRAGDYPTATAVYDTDSVGLVRILKRLNQGVDLAGKPIGQPTRFCVGVAFDMHPD
TLDREMRRLDQKIEAGADFIMTQPIFEPETLDQYLRRVGSPPLPMLVGVLPLQSSRHAEF
LHHEVPGIHIPDWVRERMARAGNQGREEGLRLAAELLDAIADRVHGVYLMPSFGRYEVVA
ELVARVRARLGLSAQVGAPRPS
>A0A0C4USI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria schmidii|TrEMBL
AYGIHLGTEMCKKILAHGIKTLHLYTLNLEKSALAILANLGLIDMTKIKRPLPWRPPANV
>A0A1Z9XXQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp. TMED17|TrEMBL
MIPDNNSAGAARAAPLVSFEFFPPKNDKMAARLWESVSRLEAMAPDFVSVTYGAGGSTRD
RTHETVRRMARETSLSPAAHLTCVSATKQDVLNVADAYWQAGVKHIVALRGDAPEGMGQK
FEAHPNGFRDSIDLIEGLKENAANNSHKFEITVSCYPESHPDSRGPDADIAFLKAKQDAG
ASRAITQFFYDTDIYLNFLERARAGGVTMPIIPGIMLQPNFEGLKRIAKLCAASLPDWLH
KLYEGTENDSETRDLITANLAAELCQKLQEAGIQNFHFYTLNKAGLALSTCHLLGLKPQT
TGVAQ
>A0A0Q4UAN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. Leaf85|TrEMBL
MPTASHHRASRDGYRPIQVSIEFFPPKTDEMEKVLWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMIKETSLKPAAHLTCVDATREEIDEVVQSYWDAGVRHIVALRGDPQDGVG
TAYRPHPGGYARTSDLVAGIKRIGDFKVSVSAYPEKHPEAATLDADIDALKAKVDAGADQ
AITQFFFENDVYLRYVDKVRAAGIEIPIIPGILPVQNFKQSANFARRTGASVPYWLAARF
EGLDNDVDTRRLIAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKV
AAAKAA
>A0A524GTG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
DGEAFSGGRLPDAPELYIGAIGTAFRPVDEWKPEKLIVKADAGAQFIQLQVCMNADAIKD
YVAKIVAAKLTWRLQILAGLAIFPSAEAAIKMKKMRPEVAIPRAVIDRLEGAADPVQEGI
AICAEILAELAGTPGIAGANLMTTGGPELIIATVRKSGVRGE
>A0A0Q7DB19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylibium sp. Root1272|TrEMBL
MSDASSSLKLPVPVSFEFFPPNTEAGGEKLKNVVRELGSAAPEFFSVTYGAGGSTRDRTL
STVRDIAALGFEAAPHLSCVGSTRAGIAEILATYRAQNIRRLVALRGDLPSGTATAGEFR
YANELIAFVRETQGHELRIEVAAYPEYHPQQRYARRDLQHFANKVKAGADAAITQFFYNP
DAYFHFVDEVRALGVDVPIVPGIMPFHNYARIAQFAMRDGIEIPRWVALKMEGYMDDAAS
IRAFGIEVVSRLCERLIAGGAPAIHFYTLNQSALTLEVCRRLAATHG
>A0A4R8W0X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. RHLS22-1|TrEMBL
MTATPTSPPADPACRSSIPFSFELYPPKTAAATTALHATIDALASARPKFISVTYGASGS
SRTSSLDVLRYIRRATTVEPMAHLTCVGSSHAEASSLIREFLDAGVRSFLALRGDPPEGL
TENDAFLGDLHSAGELVQLIHRVQAERVPYQETPIPGLPRARAVKTERDHVRIAVAAFPN
GHPRSRSTAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVQFPILPGIMPV
TSPGRLRRILELSGEELPAELSIQLEVEPTLEGQREIGISHAAALAEKLIAGGAPGLHLY
AFNQHETVLAVLDRAGALAPAQPVVSAHIPSPTHPSTSPVGTRAGIHSTKDYH
>A0A1Q3LDP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. 69-7|TrEMBL
MTAPLRLREATRRCPKRMVHGPCGGVAIDGGCEVPGIRCSFVDDPAVLHDLEFSAAEVDA
PNAARASGDALPVSPRGEASTAFAALVDADAVITADLPVRSTDPAVITEAGVRLRELTAV
IAGEPPGLRDALSLTHKALLLAAAGSRVVAGLTCRDRNRVALEGELAALADLGVSGVLAV
TGDHPASTALPQAQPVFDLDATRLTALARRAGLFVAVAEQPSAPPVDYRPVRLARKAQAG
AELGILNLCGDLAEIRRFTAALATTAAPVPVLVSVPVLTSVATARRLAALPGVGLPDELV
TAVAGADDPVDAGIAAAVAWARRALAIPGVVGIHLSAIAAAASAPTAGAADAAELTAVDA
LASAAARLRTAIATDAIATETAGTA
>A0A7X5BEN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. V29_P1S30P107|TrEMBL
MGYTHASHIDALNQSISEVSDINVSFEFFPPSTPKMEETLWNSVHRLKNLNPKFVSVTYG
ANSGERDRTHSIIKAIKEQTGLIAAPHLTCIDASRDELITIADDYWHNGIQSIVALRGDI
PLGGGKPEMYAADLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPQWMAKQFDG
LDDDPVTRQLVGASQAIDMIRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPR
>A0A7J7X628|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhinolophus ferrumequinum|TrEMBL
MVNEPGGHGGPNPCLEGSSIGRESSKVRSRCSTRGLKPERHERLREKMRRRMESGDKWFS
LEFFPPRLAEGAADLISGFDQMRAGGPLFIDVTWHPAGDPGSDKETSSMTIAGIAVNYCG
LETVLHMTCCCQSQEKITCHLHKAKRLGLKNILALRGDPVGDQWKEEEGGFCYALDLVKH
IRSEFGDYFDIGVAGYPKGHPDAGSFESDLKFLKEKVSAGADFIITQLFFEADTFCHFVK
ACSEIGITCPILPGIFLIQNYHSLQQLVKLSKLEVPQQIKDKIEPIKDNDAAICNYGIDQ
AVSLCQTLLASGLVPGLHFYTLNRTMAAIQVLKRLGMWTEDPRRFLPWAVSAHPKRWEED
VRPIFWASRPKSYIYRTREWDEFPKGRWGNSSSPAFGELKDYYLFYLKSTSPKEEELLKM
WGEELNSEESVFEVFMHYLSGEPNRNGCKVTCLPWNDKPLATDPSLMKEKLLWMNRRGVL
TINSQPNINGQPSSHPVLGWGPSGGYVFQKAYLEFFTSPKTVKALLQVLKKYEFRVNYHI
VDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIKQWGKLYA
EASPSQEIIRYIHDNYFLVNLVDNDFPLDNCLWQVIEDTFELLDRPPQTDRDMEAT
>D2YE91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio mimicus VM603|TrEMBL
MGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKNLKPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQNIVALRGDI
PPGGGKPDMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPNWMVKQFEG
LEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A2S6HJ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacter tundripaludum|TrEMBL
MQSQKTHPKLFSFEFYPPKTEEGAASLQVVHSKLAKLNPDFFSVTFGAGGSTRDKTFTTV
VDIQSKGISAAPHLSCVASTKANIRAILKDYQDNGITKIVALRGDLPSGMMSAGEFRYAN
ELVEFIRQETGDHFQIHVAAYPEVHPQAASGVEDFKNFKRKVAAGANAVITQYFYNAEAY
FHFVDACEKNGITIPIVPGIMPITQYTQLFRFSEMCGADIPRWLRKRLESFGDDRESVQA
FGLDVVSNLCQRLLEGGAPGLHFYTMNQAAPTLAILENLQIRPQD
>A0A0S8AD17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium SG8_35|TrEMBL
MNYFKELSISTSFPLCYNLLPHFAAAEQEYGALRKCVDAAMEDGRIGAFFLSDHPARRQN
FSSLHLAKDILASGGEPIVSLSLACNDRNGALEKLQEYSQAGVRQFLFVSGDYPLETDKG
RENPLSDLDSVQLLMLLTDFRKKNTIAAGCAVSPFKTFESEQVWQFEKLRRKISVGADFV
ISQLGYDMRKFDELIRFCALHKITAPLVANIFITDMQTAGLIQARRVPGVKIPGPLLRTL
YGETSDCLGPQE
>D3HAE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis (strain B6)|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>W0FNR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium Contig234|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5M9ND38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio gigantis|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A1T4N5U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carboxydocella sporoproducens DSM 16521|TrEMBL
MSRLQQLLEAGRFVVTAEVGPPKGADASTIRHHAELLAPYVDALNVTDNQTAICRLSSIA
GAFHVQAAGVEGVVQMTVRDRNRIALQSDLLGAWSLGLKNVLCLSGDHQTFGNHPTAANV
YDIDSIQFIRGLQRLREGKFFNGEPLHGEPPQFFVGAVANPFADPFEYRVLRLEKKIRAG
ARFIQTQCIFDLERFDRFMQLVRQRGLHEQAFILAGVTPVKSVRMAEYMQKNVSGMIVPD
ALIQRLKQAENPKQEAVRVVVEQIQALRQIPGVRGVHIMAVAWEEVVPEIIIQSGLR
>A0A2N7Q323|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurella sp|TrEMBL
MSIASLIAKKKLLTIEFNPPKNTDIQKHILKLEPFKNIVDAINVTDSPMAKPRMNSIVSA
NFIKDISEPIFNLTCRDKNKIAIQSDLLAASALGLKNILAITGDPAKDNDSVYKINVFEL
IKLIKNLNEQFNTGFFIGCASDIPKTNNISSIESRLKRKSEIGAEFVITQPIFSKNDLER
FLEASNNIKIHKIIGIMPIVSYQSALYLNNNVKGINIPKFILSKFENASIEDFKLITFEL
HNKLLNDIKNLLPYIDGLHIMKLDYEIAQLTKKFLEV
>A0A0K2RYJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia mucilaginosa|TrEMBL
MTTVHPALSFELFPPRSHASCESLLRTIAELEGTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSARLAGVDIPIIPGIMPVTSLKRLRNLCQMAGMEVPTDLAYALETATSDAE
LHRIGVEYALNQCRTVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLHELEF
A
>A0A7V9MEW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MSCSLRNTDTSDETVRAALALARYEVLPTTKIEGAVLESVPKSVTLTVTASPAKGMESTL
ATAERFVGHGYPVVPHLAARMISGQTELAEIVARLTAVGVNNVFCPAGDADPPAGEYAGS
LGMLQHLTEMGRPFEHVGITGYPESHPSIEDDITIQSMWDKRSHATYVVSNLCFDPDAVR
VWLHRMRKRGVELPVLIGLPGPIERAKLLAMSTKIGVGQSVKFLKSHVGVFARIAAPGGY
SPEKFLQKSADYLGDPALKVDGLHLFTFNQVAETEAWRQSLLLQC
>A0A8H5B425|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psilocybe cf. subviscida|TrEMBL
MEIDVMLPPDFLFLPPYSSSPFFLSITRPYDVMKISQKIEQSSKEGKVWWSFEYFPPRTA
QGLQNLLDRIERMRQLGPEFIDITWNAGGRTSDLTSEMVKTCQGLIGIETCMHLTCTNMP
KEKVDIALKDAKAHGCRNVLALRGDPPQGKDEWEAVEGGFVHGIDLVKHIRKDYGDYFDI
AVAGFPEHMALPREELDKEIQWLKEKIDAGVDFIFTQMFYDVELFISWVKEIRAAGITIP
IVPGVAPIQTWNGFQRATSLAKITIPQWFLDELEPYKNNDEKVREVGTRLVAEMCRKILA
ADIGIRGLHFYTMNLEKGTKMLLEELNLVPRIETIKPLPWRQSLTPNRRQETIRPIFWAN
RTKSYISRTENWDEYPNGRFGDSRSPAYGELDGYGVWIKQTKEDALKLWGHPTTFADIAS
LFSRFCSADLKALPWSDQAPAVETSVISKQLATINELGFLTINSQPAVNGAKSDDKVFGW
GPSNGYVYQKAYLEFFVSPPLLSLLLTHIERDANITYYVINKQGDLRTNTHSDGPNAVTW
GVFPGKEIIQPTIVEAVSFMAWKDEAFELGTQWAKLYEHDSPSQKLISDFVDTSFLVNVV
HNDFHDADAIFRPFYKAGADYKASMQSKHLPS
>A0A411A4C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus velezensis|TrEMBL
MGLLQDLEERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIADLGADIAGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTDKEVKIRREEEVI
SVRNERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A8H5BX04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psilocybe cf. subviscida|TrEMBL
MKIADQIAAQDARAPFYTFEFFPPRTDQGFENLVSRISRLSTLNPLAVSVTWGAGGSTKD
RSLELASLTQANGVNTILHLTCTNMEMGLIDEVLKAVKAQGIQNILALRGDPPRGEEDWI
ASDPRFTRAIDLVTYIRSVPEYASWFCIGVAAYPDGQGDGVDEDIEIARLKDKVDAGADF
IMTQLFYDADHFVSWYEKVRAKGIRVPVIPGIMPIQTFSSFNRVTKLVGTRVPDSISQKL
ASIGHDDQEVKDFGVQLAVETIQTLQNRSDIRGFHFCTLNLEKSVQRVLANLQWTIGSAA
AVGQNRLIADPADAVTQPAQAEDNADLLITPANASTSATLGLTTISRTEGEAGPGELNNA
ATWDDFPNGRFGDFKSPAFGDQDLWGGSSLSRSEALEHWGNPKTIADLTQLFLDHLHFKR
PSTPFSPTPLSEESLTILPHLESLTKRGWWTVGSQPGVDSAGSTDAIYGWGPRSGYVFQK
CFVEFFCDGEDLEQLEKRIEKSGSGWVHYFACNYAGDCRSNVPDNGRNAVTWGVFPGKEI
VQTTIIERESFLSWKDEAFAIWSEWSSFYRPASEERRLLEGVRDNRWLVNVVHHDYKNTT
ALWTFLLE
>A0A737NV69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. houtenae serovar 44:z4,z24:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7Y5WFX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MTLGSPSLDPAGRPTIRERLTAGERSISFEFFPPKDEAGERQLWTTLRELEALQPTFVSV
TYGAGGSTRDRTVHITQGIAEHTTLSPMAHLTCVGHSREELRTVIGSYAGAGVRNVLALR
GDMPEGPTAPWHPHPGGLRNAVELVEMVKGLGDFSVGVAAFPDVHPAAESAESDARYLAA
KAKAGADFAITQLFFRVDEYFALVDRVAAAGADIPIIPGIMPITSLPQITRMAELCGAAL
PDEVVERVSRFDGDPAAVRAAGVALATEMCDELLSRGAPGLHFYTLNRSRATREIYAGLR
STVS
>A0A382DFM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKITEGCFEATGHTTIICDFSPPRSGNPEAVVEAQIDADFISVAYNPGRAVRTNSAMLAA
AIQSSGKNAVFTLATRDMNKLALQSQLLGAQMLGLQNVVVVQGDPFGQQDQGRVASVDDY
HTTGLVTAIAQMNQGQDFKDGQLRSPTDFCVGATVDLSRGIEEEARLAVRKVQAGAEFLI
TQPVFNVDHVARYRESYAYQAGKAGILPIYFGLQILEKDGVLFSSVPELVCRELERGRSG
IDIALELYQKFQEARLNNIYLMPPIKRGGARNYEAAKEFLGKIIKL
>A0A6I8U6F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aedes aegypti|TrEMBL
MSFKYSPFLLGPMRNARSRSLVFVALKLHQLLLTLMAQHDARDYLTSLVDGHRREANSSS
SSRTTSIIMHHLTVESDPPNSSTDYAKGRASPAEAMHSHENSRNLKQVIQQWTSSDRLSY
SIELIPKEDFVLDLSRLSPKPMFCSLPWISDNNLQYQRFVDTPMLKMTAKIVPHCSVMNH
ISCYNITETQVDKFVDMGNWNLFVVRGDTVSENQRFKHSSDLVEYLLSKNNPDITIATGG
YPYVHPESPSMDYDVKYLKQKVDLGVDFVLTQTLYDAASYLQYVDECRRAGITVPIVPGI
FLPSSYDQLETVLNLTRVNPPKDVLTMLHSHALDEPAVFEAFVVKHFVDLVRTLRQERPD
EVKLVHFFTFNRLGLLAKVLDKIADLF
>A0A7W0M0F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MTDSRTSRAASSSSGEHRRRDALAAALRRPRVEVLPLAGTAELVEQHVPHELPVTVTASP
RHGLEPTLVLTEALARVGFSAVPHLAARLVFDDAHLTEILHRLEVAGVGDVFVVAGDGER
PVGDFTDSLELLTAMQRLRESGVARGLDQVGVAGYPEGHPLISHEDLMRALHAKQPLSTY
VVTQMCFDAKAVSSWVTGARQSGMHLPVHVGVAGAVDQRKLLRIVGRIGIGQSARFLRKH
RHGLVRLLRPGGYRPDHVVLRLAADMAEPERRMAGLHLYTLGDVAATERWRQQMLWMLRE
NEIGHG
>A0A4Q2UA90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lichenibacterium minor|TrEMBL
MTAPDTLRPSRLPGAPIRVSFEFFPPKSADAEASLWRSIERLAPLDPDFVSVTYGAGGST
RERTHNTVARLVRDTRLKPAAHLTCVGATRGEIDDVVRGYWDAGVRHIVALRGDPAGGPG
TAYEAHAGGYDSSADLVRGIKALGDFDVTVSAYPEKHPESATYDADLDGLQAKVDAGATR
AITQFFFDNSLYERYVDRVRARNIHIPIIPGIAVIQNFKQTANFARKTGASVPDWLADRF
AGLENDPATHQLVAAGVAAEQVLDLVDAGVRDFHFYTMNRAELVYAICRLLGIKPDAERA
AA
>I2UBQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 4.0522|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A369LNL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Slackia isoflavoniconvertens|TrEMBL
MHIIDIFGGEKLPVSFEIFPPKGDLPVEEAREVIGGLAPLSPSFVSVTYSAGGSGNSSRT
IDVAKMAQDEYGLNMMAHLTCMNADRAGIDSVLASMKAAGIENVLSLRGDAVPGATPKDF
KFAKDLIPVAREAGFCVGAAAYPEGHIDCLDFDESIRHLKEKQDAGAQFFVTQLFFDNDL
ALRFLDAARKAGITVPITFGIMPFLSKAQIQRMVFMCGASLPSPIIKLLARYEDDPKALR
QAGIDYACQQFVGLSKEGVDGLHVYTMNRPDIAQAAVQALRDAGAIA
>A0A2E9AN63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinisphaera sp|TrEMBL
MTHVSQNSFSIEFFPPKGPKGAARLDKARARLATLGPDFFSVTFGAGGTTRSGTLETVAA
TMKATGIAAAPHLSCIEGTKESINELLDSYKAAGVDRIVALRGDLPKGMDEPGVFSYANE
LVAHIKQRHGDDFHIEVGCYPEYHPQAPSPAADIENFVRKVRAGADSAMTQYFYNADAYF
NFVEEVAAQGVDIPIVPGIMPITDFGQVSRFSAMCGADIPRWIRQKMEGYGDDQTAVQAF
GREVVARMCEQLLAGGAPGLHFYSLNKAQPTIDLWHDLGLPLPAGRIVETG
>A0A417E6B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM34-9LB|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A238VLF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloechinothrix alba|TrEMBL
MARTDSRPRRRRAVAGLLDQPRYEVMPLSNVFDEVGCLPRGAVVTVTSSPHKGADATIDL
AVRLAGHGVRPVPHLAARQVRDRVELAGFLHRLEAAGIDDVFVVGGDAREPAGEFGDGLA
LLEAMDSIGHRFDHIGIPSYPDGHHAIDDGRLWAALQAKQRYATYTVTQMCFDAAAISRF
TLALRRHGITLPIYAGIPGVVDMAKLLRVSLRIGVGDSLRFARGNKAASRRLLTPRGYRP
DALVRKLGAHVHDGKAELAGLHIYTFNHIDATVRWMQTARRKVAS
>A0A4V6NDM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylobacter aquaticus|TrEMBL
MSSDVERRSRRAGGRPISVSFEFFPPKTPDMEATLWNSITRLAPLAPKFVSVTYGAGGST
RERTHTTVERIVKETRLAPAAHLTCVSATKGEVDEVVRGYWDAGVRHIVALRGDPPGGVG
QAYDPHAEGYRTTADLVAGIRRSANFEVSVSAYPEKHPESPSFDTDLDILAAKVDAGATR
AITQCFFDNDLYFAFLDKARARGIDVPIVPGILPVSNFKQAKNFSTKTGTYMPDWLAARF
EGLDNDPETRKLIAAAVAAEQVFDLVDRGVTEFHFYTLNRADLVYAICHLLGIRPPQENG
ASGHGNGAAAA
>K9XNH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gloeocapsa sp. PCC 7428|TrEMBL
MIAVNKLQTLLNADHFVVSAELTPPRHYKIKPLISKAEKIAAYVDAVHLNDNALSQARLS
NVVAAHLIQQIGIEPVVQLTLRHKNRIALQSDLLGLAALGIRNIMILGGYPCSIGSDPEA
KEANDISAIDAIAAIHNLTTYGKMFNGDTIAPAPDFYIGTIALPYAAPDKLEESMALLEA
KIARGARYIQLQATFDLAAMQQWMAEVVKRGLHQRVHFIGAIFPFSSWKGLEFLQKMPGF
YIPHEVVERIRRGDCKSESLKITLELIQGMQAIEGIRGVHLRLIGSSDCSQIVELAGLRQ
FASNHFGEAFPLS
>A0A1C4PJV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DvalAA-14|TrEMBL
MAFGTPSTRTDRALTIRELLARGERSYSFEFAAPRTEKGERTLWNAIRRIEAVGPTFVSV
TYGAGGSSRDGTIRATDRIVSDTTLTPCAHLTAVNHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPLADWVPHPDGLTYAADLVRLIKESGDFCVGVAAFTEMHPRSTDPAADTRHFVD
KCRAGADFAITQMFFDAEHYLRLRDRVDAAGGTIPIIPEVMPVTNVKQIERFAQLGNAPF
PPDLAERLLAVADDPAAVRAIGIEFTTEMCRRLMAEDIPGLHFITLNHSTASLEIYENLG
LHQRAA
>A0A1G0AS47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium GWA2_54_124|TrEMBL
MSISHISFEFFPPQTVEGVEKLTIAREKLATLNPEFFSVTFGAGGSTRDRTLETVTQIKV
EGFDAAPHLSCVGSTRDNIRAILKTYRDAGIRRIVALRGDLPSGMATAGEFQYANELVEF
IRTETGDHFHLEVAAYPEVHPQAKSARDDLINFKRKIDAGADSAITQYFYNADSYFHFVD
ECQKLGITAPVVPGIMPIVRYSQLARFSDACGAEIPRWMRKTMEGFGDDNESVQAFGRDI
VTAMCEKLLAGGAPGLHFYTLNQAAPCLAIVERLK
>A0A662CHF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquificae bacterium|TrEMBL
MRVRDILKERDLAISFEFFPPKSHQEEEALFENLERLKKWNPAFVSITYGAGGSTHDKSL
EIAYTMKEQGLNVVAHLTCVGATKEDLARTLDWLAERGIENILALRGDPPQGEKTFRPVP
GGFQYAYQLVEFIKRGWDFCVGVAGYPEGHIENPDKEADLRYLKLKVDKGADFVVTQLFF
DNRFFFDFLKRAKAIGIKVPIIPGIMPITNLKQVMRFTQLCGATIPRALLEWLEEGSTPE
EVRRRGIEHAHLQCKELVERGIKALHFYTLNRSRATEEILTRLLGEPEV
>A0A3N0IHW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Slackia isoflavoniconvertens|TrEMBL
MHIIDVFGGEKLPVSFEIFPPKGDLPVEEAREVIGGLAPLSPSFVSVTYSAGGSGNSSRT
IDVAKMAQDEYGLNMMAHLTCMNADRAGIDSVLASMKAAGIENVLALRGDAVPGATPKDF
KFAKDLIPVAREAGFCVGAAAYPEGHIDCLDFDESIRHLKEKQDAGAQFFVTQLFFDNDV
ALQFLDAARKAGITVPITFGIMPFLSKAQIQRMVFMCGASLPSPIIKLLARYEDDPKALR
QAGIDYACQQFVGLSKEGVDGLHVYTMNRPDIAQAAVQALRDAGAIA
>A0A2T5KBZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cereibacter azotoformans|TrEMBL
MARPRISFEFFPPQTLEASFRLWETAQMLAPLKPDFVSVTYGAGGTTRKLTHDAVETIHN
HYKLNVAAHLTCVDATKAETLEIANSYAEAGVTEIVALRGDAPKGAERFTPHPEGFANSI
ELVEALAATGKFKLHVGAYPEPHPDSADTLADVRWLKRKIEAGASSAITQFFFEADTFLR
FRDLCVKEGIRAPIIPGILPIENWSGVKKFAARCGAQVPGWLDEAFANAKRDDREELFSV
ALCTELCDRLLSEGVEDLHFYTLNRPTLTREVCHALGILPEVALQNVA
>A0A436KSX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.04.1.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A2D5X6W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLTTFDELNQLSPTYFSVTYGAGGSTRDRTLSIVQALLE
RSDTPVAPHISCIGDDKAEVAELLDLYKALGITRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSADHFHIEVAAYPEMHPQAKSFLFDIDNLVNKYKAGADTAITQFFYNADSYLHLR
DALEQRGIDTVAQPLVAGIMPITNSSNLIRFADSCGADIPRYVRRQLADFGDDRKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLVSDELVSNDLSSKTLSSESA
SV
>A0A8H4INE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryosphaeria dothidea|TrEMBL
MSISAKLHEGRKTGKPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPTFIDITWGAGGRNS
HLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALREAYNAGCKNILALRGDPPREKEK
WEATAGGFRFAKDLVKYIKDNYGDHFDIGVAGYSEGCDDQDDPDLLLDHLKEKVDAGGTF
IVTQMFYDVDIFLNWVKKVRAKGIDVPIVPGIMPIHTYAAFMRRAQWTKCRVPPEWLEAL
EPVKNDDAEVREVGRHLIATMCRRLMEAGILHLHFYTMNLAQSTRMILEELGLTPDIQSP
LEKPLPWRQSLAPGRREENVRPIFWRNRNRSYVVRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNIKLWGKPKSVRDIANLFVRYMEGKLDNLPWSEQPITAEADVLKNDLVN
LNQRGLLTINSQPAVNSAKSSDPVHGWGPHNGYVYQKAYLEVLVSPELIAELLTRVERDP
EMTYYAVNKAGDLKTNAPSDGPNAVTWGVFPGKEIIQPTIVEIISFLAWKDEFFRLGEDW
AKCYTHASPSRYVIEDLMDTWYLVNIVHNDFHVSSGIFALFEGLEVKDIDKEPHGSAEVE
VNEKINGASHTNGVSKVPDTVVNGNSTSAVQNGTANH
>A0A7Z0RJY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium changzhiense|TrEMBL
MALKNEARGSNIRVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPIVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIDDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRRAAKSAGAAA
>A0A2N5G1B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. UMB0728|TrEMBL
MSLLDKMEKEIIIADGAMGTLLYSYGTDFCFEELNVSQPGHIQNIHQAYIDAGATLIQTN
TYAANYLKLQRYGLEDHVKEINSAAVTVARKAAGNHAFVAGTIGGNRGIKPHSISIEEIK
RSFREQLYCLLMEGVDAILLETYYDLKELETVLSIARKETALPLIAQVSLQETGIMQDHT
PISEALSRLDALGADIVGLNCRLGPHHMLLTLEEVPLPQKAYLSAYPNASLPAYTDGKFH
YEGDAEYFRQSAKAFRNQGVRLLGGCCGTTPAHIRAFSDELKGSPPLEKKEVREPKAKIR
IMPKEAQRDLPPLQDLVKKRQSVIVELDPPRKLETDKFFAGAKALQDAGIDAITLADNSL
ASPRISNEALGYLAKNRLGLRPLIHLTCRDRNIIGLQSHLMGLHTLGLHDILAITGDPAR
VGDFPGASSVYDMSSFELIQMIKQLNEGRSISGKDLGQKAAFSVAAAFNPNVRSLEKAVQ
RLEKKAECGADYFITQPVFSEEKLMEIYEATKHMEQPIYIGLMPLTSSRNADFLHNEVPG
IKISDKIRERMNSLKDDPLQSVREGISISKELIDAAAELFNGIYLITPFMKYELTAELAA
YARSEKLKTARRSRNAKDFSI
>A0A839UGM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium trifolii|TrEMBL
MSFFRQSRRSDIGSIIRVSFEFFPPKTEVMEERLWETVTRLAPLNPEFVSVTYGAGGTTR
ERTARTIKRILTETDVNAAAHLTCVDATKEEVDTVVREFAAMGVKRFVALRGDPAGGVGA
HYKPTPGGYENGAELVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVEKVRRAGIYIPILPGILPIHNFTQVTNFCSKAGTHIPAWLAERFD
GLDNDPQTHALVSSAVAAEQVLDLVERGIQDFHFYTMNRADLPFAICHLIGVRPGSSDTV
DASLAGAAA
>A0A1F8QW12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_56_8|TrEMBL
MTHPLLDRLARGPILCDGAMGTLLYARGISFERCFDELNLSNPALVLEIHGDYIHAGAEM
IETNTFGANRFKLAHHGLEKKVREINLRGVKLAREAREIAGEATFVLGAVGPIGQLLVPL
GQITYADAHAAFKEQIEALLEGGADAIILETFSDLNELKTAVTAAREVTRDLPLFAQMSF
TDDAHTLTGNTPEEIVAALCELPVDVIGANCSVGPAGTFHAVRRMTAALSKSEVGSGKFE
VKPYTSHLALPTSHFLSVMPNAGFPARIAERYMYLSSPQYFAEYTPKFVGELGATIIGGC
CGTTPAHIAAMRDALELIVPTTERRVTNVTSVVVVEKLQARPPEALTHELASVPRTLREK
LRAGKWVTSVELDPPRGLNPTKMLQGAAMLKELGVDAINIGDSPLAKIRMSCISLAIMIQ
QQFGLETIIHYTTRDRNLMAMQSDLIGAHALGIHNVIALTGDPPRLGDYPNATAVYDIDS
IGLIKILKRLNQGRDWAGTSIGTNADFFVACALDMMWANSDPNEIDRFHRKLEAGADFVM
TQPIYDAAILREFLQKYGDKYGAIAEPIILGVLPLMSAKHAEFLHNEVPGITLTDEARRR
MKGAGDRGVEEGIKLAQELLTQAKDLVAGTYLMPSFGRYEVCGELVKLVN
>A0A6G7JC45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus paralicheniformis|TrEMBL
MGFLEDIKSKTLIADGAMGTLLYSYGIDRCFEELNISKPEEVRRVHEAYVQAGADIIQTN
TYGANFIKLSRYGLEDETKQINEKAVRLARSAAGSAYVLGTLGGIRTFNKNSYSLEDIKR
SFREQLYLLLNEQPDGLLLETYYDLEEACEVLKIARKETELPIILNVSMHEEGVLQDGTP
LADGLKQLASLGADVVGINCRLGPYHMIRALEEVPLLEDAYLSVYPNSSLPSLVEGRLVY
ETDDEYFRESAAEFRNQGARIIGGCCGTTPNHIRAMAEAVKGLPPVTEKRVKIRKKAALA
VQNERTEPALDDLAKQKRSIIVELDPPKQLNFEKFLHAAEELQSAGIDALTLADNSLATP
RISNVACGALLKQRLDMRSLIHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRLE
KKIACGADYFISQPVYSEEQLIKIHEETKHLETPIYIGVMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGNDKQKQAEEGLAIARSLLDAACDLFNGIYLITPFLRSDLTVELTAYIH
QKEKEKTNV
>A0A6P9B4X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantherophis guttatus|TrEMBL
MELAEKTPLARAFTMVNESHGEFPPMSNGLSVTRSNGSNSSSSGESSQNSSRCSTPVLDT
ERHERLREKMRRRQESGDKWFSLEFFPPRTANGAVNLISRFDHMGAGGPLFIDVTWHPAG
DPGSDKETSSMMMATTALNYCGLETILHMTCCNQNRETITAHLQKAKRLGLKNIMALRGD
PIGEEWEEELEGFNHAVDLVKHIRQEFDDYFDICVAGYPGGHPEAESYIDDLKHLKEKVS
AGADFVITQLFFRTETFLKFLTDCQAIGISCPVVPGIFPIQGYHSLRQLVKLSKLVVPQE
IKDIIEPIKDNDAAIRNYGIELAVKMCRELLDSGLVHGLHFYTLNREVATMEVLRRLGLW
KEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGE
LKDYYLFYLKSKSPREELLKMWGEELISEESVYEVFRCYIAGEANRNGHKVTCLPWNDDP
LAAETNLMKDELVKVNRRGILTINSQPNINGKPSTDPIVGWGPEGGYVFQKAYLEFFTSA
ENIKALLAVLKKYGERVNYHIVNVKGENVTNAHEMQPNAVTWGIFPGREIIQPTVVDPVS
FMYWKDEAFALWIEQWAKLYEEESPSRMIVQYIHDNYYLVNLVDNDFPLDSCLWQVLEDT
YEQLNSPGKEEKTSGF
>A0A7Y6NIV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea brenneri|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEATLWTSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATREELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPEMYGCDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMNAMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVAAA
>A0A1C6V054|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora yangpuensis|TrEMBL
MALGLPSVLPPEPAIGELIRARRPTFSFEFFPPKTAQGERLLWQAIRELEPLRPSFVSIT
YGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVRG
DPPGDPGGEWICHPEGVRYAEDLVRLVRESGDFSVGVAAFPHKHPRSLDVTSDTEYFVRK
CRAGAEFAITQMFFDADEYLRLRDRVAAAGCDTPILAGVMPVTQMSTIERSAQLSGAPFP
AALAERFDRVRDDPEAVRRLGVEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLQV
GARV
>A0A2A5S169|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus plantarum|TrEMBL
MKITDIYKTKNKKDKAVISLEIFPPKTDAGVETIYKTVAGLTHKPDFISVTYGAMGSATQ
ENKTLKIAEKIKKDYGIETMHHLTSINNDPEEISKILSDIKAKNVNNILALRGDRPVGAE
ISKLPDDYHYAYELIEDIKKNGDFDVAAAIYPEGHVNSALEVENIEHVKRKYEAGANLFV
SQLFFDNEKFLRLNDYIRHSGIEAPIAAGIMPVLQKSQIERMIFFGASLPTRLIKIVNKY
KDSPDDLQKAGMEYACKQIDDLLARGVDGVHIYTMNKPFVANTMMEHYL
>A0A5C8ZQQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parahaliea maris|TrEMBL
MAKQKPRISFEYFPPKTAEGKSKLLEETTPALQALNPEFFSVTYGAGGTTRDSTRGVVSS
IRAAGIDVAPHLSFGGDDENAVGELLDTYVERGINRLVALRGDMPSGMGASTQLVYANEL
VEFVRKRTGDHFQIEVAAYPEIHPESESYDSDIHFLKQKLDAGANSAITQYFYNVESYFY
FLDQCAAAGIDKPIYAGIMPITNFANLARFSRNCGAEIPRWICQRVEGYGKDTDSVRKFG
IEVVTQLCQTLLESGAPGIHFYTMNQVEPTRTIHANLGL
>A0A415RSK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF33-16|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFNTPSVAHLTCVGRSHADIVAKIDEYRSAGVENILALRGDLPTGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A061JU55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri KOS6|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKTELRELLNLYQSAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLTNFVRKAQAGADSAITQYFFNADCY
FYFVERVRRLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLKLSG
>A0A345R2B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. SK025|TrEMBL
MTSPAVSFEVFPPKSVDASFRLWDTAQALAPLAPRFFSVTYGAGGSTRDLTHDSAHVLRR
TSGLPVAAHLTCVGASKAETLEVADSFAEIGVTDIVALRGDPENGASTFTPHADGFADSV
ELIEALAKTGKFTLRVGAYPEPHPESHDQAQNVEWLKRKFDAGADEAITQFFFETETFLR
FRDACAAAGITKTITPGIMPVTNWKSARNFATRCGASVPAALDEAYAAAIRDDRHDLLST
ALCTEMCSELVSEGVENLHFYTLNRPELTRAVCRALGVTAQTSLSDVA
>L1PFH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. oral taxon 181 str. F0379|TrEMBL
MPPRKESLVKPFWQTVERLLSVSPDFLSVTYGAAGQDRHSARGVVRKLVKDSPVQPIAHL
TCVGTTPSEVSEVVTDYLNAGVRTFLALRGDPPVGRPDWQPSPGGVSSATELVTLIRSIE
AARCAQYPGAALRAAFKPLTIAVATFPAGNPAAGTSPTQEVERLLVKQSAGASFAITQLF
WEADTYVNFLEKARSNGVTIPIVPGILPPTDIRRVNRMTELTGVVFPEYLRRKLESASSP
QEMYSMGVEIGGRLARDLHDSGAPGIHMYTFNKAAPALDVLDAAGLVSASQC
>A0A1M7KFI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWR3|TrEMBL
MKIIDILKQDKMSLSFEVFPPKKETSFENVKAATESIAALGPAFMSVTYGAGGGVSHFTL
DIAKNLKEKFNIPMLAHLTCVSSSKETVHQRIDDMKAAGIKNVMALRGDLTPELIEKGRD
NCDYHYAVELIRELKAADADFCIGAACYPEKHPESANQAEDIKHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKSF
>A0A143GA56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas yamanorum|TrEMBL
MTMSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGAGGSTRDRTINTVLQ
LESEVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYAN
DLVSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNAESY
FYFVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQA
FGEQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A533I7G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus denitrificans|TrEMBL
MNTPAVSFEFFPPRNLDASFRLWETARALAPLGPDFVSVTYGAGGTTRKLTHEAVTALSN
HYGLNVAAHLTCVDASRDETMQIVDEYAAAGVREIVALRGDAPQGQGEWVAHPDGFASSV
DLIEAIAKRGDITIRVGAYPEPHPESPDTAADVAFLKRKVDAGATSAITQFFFDADTFFR
FRDACVTAGIDVPILPGILPIQSWVGARKFAARCGTSVPDWAISAFEAAGKEGEAQLALD
LCVKLCGELAAGGVDHLHFYTLNKPDLTLAVCRQLGLRENGLAA
>C2SQ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus BDRD-ST196|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKDAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A3D4GR92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MANTFLQVLDERIIVADGGMGAMLGARGVPWNACFEATNLSQPELVKALHLEFVAAGSEL
IETNSFGANRNKLAALNQADQVKTINAAAVRLARSIVSDNVFVGGSVGPYGRLTDPEYDL
SDEERFDVFKEQLEVLLEEGVDLILLETFTQLEELKTALRATRSLDSDIPVVCQMAFSDS
VRPSVGAGAVQGLLELEALGASVVGGNCGSGPIGLIRVIEEISHLTEVKLSAQPNASFPQ
YVNGRYIYLSDPKYFAESAETLVGLGANMIGGCCGTTPDHIRLVAEQVKGWAPAQRVLRP
RIQLQENRRIKKGPSRKQIYSPIERVGTTNVTLVEVKPPRGLALGAVRRAAKLLSDSGVD
AFSLVENSLAQVRMSPIPLAHILQEEFGIASVVHVTCRDRNLMGQQSALTGAAALGIRTV
LALTGDPSTIGDSSESSSVYDTNSLGLIDLLSNLNKGINVAGNRISGSGNFMIGCAFNPN
VRRMEPEIKRLERKVARGACFAMTQPVFDAGLIEEMYDKTSHIGIPILLGVMPLTTYRNA
SFLHNEVPGIRISQEIMDRMRNASEDEASDQGLEIARELLDAATSIAPGFYIIPQLEKYE
VAVNLVQHLKQSESALAREAP
>A0A256Y5X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aenigmarchaeota archaeon ex4484_52|TrEMBL
MGNKKILWNYHVRCYYLTGQCNLVVKKNSEICGSFNLDLDAQIDKLKSVNIDFFSIVDSP
LSRPLMSPIALYHKIEENKKTAIMYFTCRDSNLVAIEGDILSTYALGIKNILALTGYLAK
NTKGVFEFSSCGLM
>A0A7W1EN76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
MSTTALRRLVDPDAVVLFDGAMGTMLYARGVFINQCYDELNLRAPDLIREVHKAYVKAGA
EVLETNSFGANRLKLAQFGLAPQTRELNKRAAELARESIPEGSDVLVAGAVGPLGVRLEP
YGSTSAEEAREIFQEQMEGLREGGAQLFVLETFSDLHEIGQAIAAARAVDPGMPIVAQMT
IGADGLTPYGASPEDVARALDRFGADVIGLNCSVGPQTILEAIERMAPVTSLKLVAQPNA
GMPRDVSGRQMYMASPEYMANYARHLVQAGAKVVGGCCGTTPEHVHAMCEGVRPLSPRFA
RAAASDVAGGATVAVREAPRTPDVEAIPLADRSRWGSKIASGTFVTSVEIVPPRGVDASR
MLADVALLKTAGVDAVNVPDGPRAQSRMGALLTSLLIEQQVGIETVTHYACRDRNLLGML
SDLLGAAAVGLRNLLLITGDPPKMGPYPSATAVFDIDAIGLTNLINKLNHGLDPGGNAIG
APTSFAIGVGVNPVAIDIEHELRRFTWKVEAGAEYAITQPVFDVEQLESFLAKLDSNRIP
IIAGIWPLVSLRNAEFLANEVPGVMVPPHIIDRMRRANEKSKEHGVQEGIAIAREMLERV
RPSVQGVQVSAPFGRVELALEVFADTLASAQL
>A0A496SSX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
KGIENIMALRGDPPQDVSDFDPTIGDFVYGRDLVDFIKREFGEYFCIGVAVYPEGHIESS
SIEEDMEYTKQKIDAGADFAVTQMFFDNRYFYQFIERAQKYGIRIPVLPGILPLTDVNKV
KEFASICRTTIPTKIEEEMLRFENNPEDMKKVGLDFTIRQCRDLIKNGFKRLHFFTLNKS
GVITKVLEAIK
>J7EQ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nicotiana sylvestris|TrEMBL
MKVIEKIQEAAKDENRVVFSFEFFPPKTEDGVENLFERMERMVAHNPSFCDITWGAGGST
ADLTLEISKRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKINGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDVIPANGIATQEIYENDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPEEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMKKSALSILMN
LGLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTLGWDEYPHGRWGNAQN
PSYGALSDYQFMRARSRDKKLQEEWVVALNSVEDTYEKFKDYCLGKLRSCPWSELDGLQP
ETKIINEKLGHVNTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSGEKL
NTLVEKCKAFPYLTYMAVNKEGNWISNISQTDVNAVTWGVFPAKEIVQPTVVDPASFMVW
KDEAFEIWSRGWAQLYPETDPSRKLLEQVQNSYYLVSLVDNDYINGDLFSIFQDI
>A0A1A9M7T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas floridensis|TrEMBL
MTDPDTPSLASTITEAYSLEVSAKHIAGLATAAPRIMRGSTIAIPYLPNQDDDARLAAAR
MVRALGFQPMPHLSARRIASRAELHTFVSRAAQEAGVERCLVIAGDPPAPVGPFADSLSL
IDTGIFERSGIQTIAVAGHPEGHPSMPAIDRWEVLDRKCRSIAERGMTPLIVTQFAFDAD
IVLTWLQALRTRGVAHPVRVGVPGPAGVAVLARYAASCGVGACASMLSKYGISLGKLFGT
AGPDRFVDRLANGLTEAHGDVSLHFYPFGGIAQTVAWVERYRSSAVRVRLD
>A0A1J5IN89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium CG2_30_58_14|TrEMBL
MKNEKPFHDQLKSGDFIVTAEYLPKAETAGTAIEAALQALAEVPSAVNVADNPFGVSMSS
LAASVILARSGIEPICQVVTRDRNRIAIQSDLLGAAALGIRNILCLSGYHQTLTDNPESA
NVYDLDSTQLVGLVKKMRDQGELLNGERINGPFPVIAGAGANPCLKPMDLGIIRLMQKVE
AGADFIQTHAVFDVEGFRLWLEAAKQAGITGKAAILAGVFPLESAEEAETLAKKYTEFQI
PAPVIERLKSAGDREAQKKEGLAICVETIDKLKSMNGLRGIHLLTGGKEETLPAILSASG
WSVKR
>A0A3S2EC82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.03.2.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A4Y3IPH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio comitans NBRC 102076|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASRDELITIADDYWKNGIESIVALRGD
IPPGGGHPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIVPGILPVSNFKQASRFAAMNHVKVPGWMAQQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQKAAV
>A0A0J0YN47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. ABG|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQDLYDNIDPLMEFNPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCHYLGINN
LMALRGDAMKDEQSFVPKAGGNSFAIDLVKQINELNQGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLRRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQKHLQILPQIFRIDLPEDLIHAVDQCKNNAEIKQVGVEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASHIF
>A0A652NE19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc litchii|TrEMBL
MTKIVEIYKTKPAPVLSFEVFPPKKEGGIESLYKTLGELDLKHVGVDYISVTYGAGGSDN
HEKTREIASYIQKNCDITALHNLTGVNQTPKLLKENLAEIKLAGIENIFALRGDLPSSDY
VNEYYPYAKDLIQEIKQDGRFSVGAAIYPEGHVDNPITGISVNGVKEKVIYGTEFLISQL
FFDNSVFYNMQEALKENYIKVPVSAGILPIISRAQVERITYMIGSSLPARLTKIVHKYGD
HPEALQEAGMEYALQQIYDLLDHGVDGIHLYAMNQPKVLKTMLPKINEYIQSKKLTR
>A3IQG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocosphaera chwakensis CCY0110|TrEMBL
MINQFRQAAQNKEFLITAEVTPPKGGNPSRMLNMAKQLKGRVHGVNITDGSRAVLRMSSM
AASALLLQYGIEPICQMTCRDRNVIALQGDLMGAYALGLRNILALTGDPVKAGDHKKARG
VFELESVRLLQMIDKLNRGIDFNDKPLPDEPLDLFPGAAVDPQCGSWSGLQRRFERKVAA
GAKFFQSQLITDFDRLDKFMHQIAANTDKPILAGIFLLKSAKNAQFINKNVPGVEIPESI
IKRLADAEEPLKEGVKIAAEQVKLAQQLCQGVHMMAIKREDLIPEILDQAGIAPIVSK
>A0A7W0LVB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MRIDEILAERRPVFSLEFFPPKTEEGHTNLRATLDTLRHDRPDFVSVTYGALGSTRDRTI
DIVKWIKQDLGIEAMAHFTCVGATAGQLRETLTEIEAAGVDNVLALRGDPPEGQGEWTQT
EGGLRYSTELIELLGEHFDFAVGAAAFPEVHPQAESPEADITFLKAKQDAGASFLITQLF
FDNEFYFDFVARAREAGVTVPIIPGIMPVTSVRNIKRITELCKSEIPDAFEHELQTRAED
SDAVHDLGIAYATLQCMDLLARGAPGIHFYTLNRSPATRA
>A0A7X8I3B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MEESNLERLLKEGHFVVTAEIGPPKNADARVLRNKAGLLKGFCDAANITDNQTAVVRLSS
FASSVHILHEGVEPILQMTVRDRNRIALQSDLLGAYSLGIKNVVCMSGDHQVIGNHPESK
GVYDIDSTQLIKAVWDMKCNKKFMNGEAIEDAAPNYFIGAVASPFLEPEELNLLRLEKKI
SEGAGFVQTQCIYDMKLFEQWMAKVRGLGLHEHCFILAGLMPLKSHKVARYMQSNVPGVK
VPETIIRRMERAEDPLKEGIRIVIEQVNWLKTIDGVSGVHIMAVNWEEVIQEIVTAAGLY
PRPD
>A0A7Y3KZA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MHPPVIDIPETYARAGRPVFSFEFFLPKAPEDLDAFVASVRALKDLAPDFVTLTYGAGGS
ARERTVEAAGRIQRETGLTTACHLTCVAHTRAELSAILDRLAALGIGHLVALRGDAPKDA
AAGPTELAHAVELVRLARARGGFKLAVAAYPEKHPESPSPQEDLKRFVEKAAAGGDWAIT
QLFFDAADYFAFVSRARAAGVLAPIVPGVMPVTGYAQLKRFTALCGARIPAELDARLSSV
QDDPAKVAAVGVDWAARQCRALLDGGAPGVHFYTLNRSSSTSQVLARLRRA
>W0FH04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium Contig19|TrEMBL
MVENRFKDALVNGEFCVTCEIIPGRGAREDGQEKEFAEAKRIYETGRVHAMSITDNPGGN
PALLADTLGKEFLDQGMVPLVHFTCKDRSRNQIIAQLYGLERQGVENLLLMTGDYQVSGW
DGRARPVYDLDPVHLNMLCTEMNKGLIVPGRKGDMQEKPTHFFNGAVVNPFKYLEGEVIP
QYLKMEKKLIAGANFLIIQLGYDSRKMDELIRYRNERGYNTPIIANIFLLTRGAAKLMRA
GGIAGAYISDELMAQLDEEAKAEDKGKGARIERAAQMIAIAKGLGYAGVHIGGFGITAEM
FCGILDRAAELEPEWKECYKKVNFGKKGGYYIYEEEKDADGKGTGFNTDKHAPKPEQARS
SKVFSKWGISRFAHHWMLTLGKRGNKVLTSRMDSLDRKKGVYRHHGLEHTGKSMIYGCMD
CGDCGLEATLYTCPMTQCPKCQRNGPCGGTYDGYCEVFPGGERFCIWYKAYHKAKKSNEM
ERITSYITPPNHWELFGSSPWSAYTHRRDNCEGRIPVKIGLETGVPGGVTPETDMLWKVK
VDVQSKPAQP
>A0A017TBA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chondromyces apiculatus DSM 436|TrEMBL
MTPARPAAPFLEALQRSILVFDGAMGSLLYERGVFVTQNFEQLNVTRPDIVKKIHGDYVD
AGAQVIETNTFGGNSFRLERYGLVNEVRSYNLAGARVAREAAGSAAYVAGSIGPTGIVPG
VATQEDLRAAASTFAEQAAALVEGGADLLMIETFRHMEELRIAIDAARRAAPGTPILASV
TFDAGGTVADGSQPEGVAAMLRDFGVDAIGINCGDGPQLALSMAERMRGTGLPLCAQPNA
GLPRTVDGRLLYMATPEYFDVFTRRIIQAGAQMVGGCCGTTPEHIRWMVKSARMLGGGAT
PAAAARPKAAPVEVIGLDPIPLAERSRLASKIAAGQFVVSVEVNPAPGLSPDSALAAAKM
LIDNGIDVVNVADGPRATARMSNLAFCALLIQRYGIEPILHVCGRDRNLIGQMAHLLGAS
AVGIQNLVVITGDPPKIGDYPEATAVYDLDSIGLLNMASTMNRGLDPAGKRIAGGQTSFL
LATGLEPGAQDLGKEIQRLERKHAAGAEIVMTQPIFQQELLDEVLRRIAHLNMPVLIGVL
PLVSYKNAEFLHNEVPGMQIPEAIRERMRKAPPGAEARKEGVRIAREMLFSVRDRVQGAY
LMPPLGKYELALEVLDGLK
>A0A665UIZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Echeneis naucrates|TrEMBL
MVNPGSCRSDSSGASNSSGDSSKDSSRCSTPVLDADRSDRLRDKMRRRMESGDRWFSLEF
FPPRTESAAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLES
ILHLTCCNQTKEKITSHLAKAKRLGLKNIMALRGDPIGETWEEEEEGFNFAVDLVKHIRS
EFDDYFDICVAGYPTGHPEAESYEKDLRHLKEKVDAGAGFVVTQLFFQAESFLKFLEDCR
AIGITCPILPGIFPIQGYQSLRHLVKLSKLEVPQEITQVIEPIKDNDAAIRNYGIQQTVK
MCRELLDSGKVPGLHFYTLNREVATIEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRP
IFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEDLLQMWGEE
LMNEESVFDVFTCYITAQPNRNGHKIMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINS
QPNINGKPSTDPIVGWGPPGGYVFQKAYMEFFTSSENVTALLKVLKKYEPRVNYHIVNVH
GRNLTNAPHLQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFGLWIEQWGKLYEDESP
SRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFKLLDAPPEPLQDIN
>A0A7U9FS41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus hominis subsp. hominis C80|TrEMBL
MSRLLNHLKNNVLVADGAMGTILYSEGLDTCPEAYNLTHPNKVERIHRSYIEAGADVIQT
NTYGANFEKLKVFGLEHKVKEIHKAAVQIAKRAANKETFILGTVGGFRGIKQEDLSLSTI
QYHTDNQIDTLIEEGVDGLLFETYYDLDELTSVITATRQKYDIPIIAQLTASNTNYLVDG
TEINEALKHLIECGANVVGLNCHHGPHHMQRSFSHIELPEHAYLSCYPNASLLDIENSEF
KYSNNAKYFGDVAQELINEGVRLIGGCCGTTPEHISYIKESVKHLKPIKTKKVIPIHRTI
NTNAKRTLKQNLTSKVKQRPTVIVELDTPKHLDTELFFENIGKLDEANIDAVTLADNSLA
TVRVSNIAAASLIKQRYEIEPLVHITCRDRNLIGLQSHLLGLSLIGVSEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINVDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMSYFITQPVYSKEKIKEVYEATKHLDTPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYLITPFQRIDYSLELAAY
SKAITQNKEAIS
>A0A316X2S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium phosphatilyticum|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIEN
IMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEDQACDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKRHLKLLPQVFKIDLPEELIVEVENAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>R7HP94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. CAG:279|TrEMBL
MPHIICSGFSKVETEYALIDLNFLGINNLLLLRGDKAKHENRFVPNENGHAHASELQEQV
NNFNNGYFIDGTKMDIMTDSRFSYGVAGYPEKHDEAPNMDIDLMFLKDKVDKGARYIVTQ
MFFDNQKYFDFVDRCRAIGITVPIIPGLKPIVIASQLTILPKVFHVDLPTDLATELLKCK
DNVEAKQIGVEWCTMQAKELMDRGVPSIHFYSLNATESVRQVAKSIY
>A0A536TSD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MESQKKHPRTFSFEFFPPKTPEGMEKLRATWKQLAQLKPRFFSCTYGAGGSTRDRTLETV
LEIQAAGHRAAPHISCIGATRADIAATLELYKSKGIGHIVALRGDLPSGAASAGEVRYAS
DLVALIRERNHFHIEVACYPEFHPQARSPREDLASFKRKIEAGADAAITQYFYNIDSYFR
FVDDCEALGIDLPIVPGIMPIGNFSQLARFSDNCGAEIPRWLRLKMQSLGDDVASIRSLG
LDVVTELCDRLLSAGAPGLHFYTMNQAGLTSTIWQRLDL
>A0A1Y2JL54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium japonicum|TrEMBL
MTDLTTPARAEGQDGHLQNGHLSSKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFV
SVTYGAGGSTRERTHSTITRILRETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVG
LRGDPAGGIGAPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDT
LKAKVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAG
TSVPDWLAEKFDGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISH
LLGIRAKSAQKAA
>A0A349PC09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MKVTQRLKTGAKVFSFEFYPPRTAEDTAKLFNTAVELKALSPDFVSVTNSSSGVAPYRTV
ALCAVLKAQFGLEVVAHLTCLAHTRGEIAEICDGLKKMDIASVLALRGDPHNVDSGARRR
DYDHAAQLIADLKKAGGFAVGGACYPEKHPEAATLEADIARLKEKVDAGAEYLITQLFFD
NAFYFRFLEKTAAAGISVPILPGLMPITGYKQMQNFTKLMQVSVPAALKAGIERWEGDKD
GMFKFSVEYASAQALELLKGGAPGLHLYTLNRSRAAMAILKNVKTTV
>A0A2S1QC67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dokdonia sp. Dokd-P16|TrEMBL
MTKVRDHIAKAIEEKRTDFSFEILPPLKGQNINTIFDNIDPLMEFKPPFIDVTYHREEYI
YKEREDGLLEKKVVRKRPGTVGICAAIQNRYQVDAVPHVLCGGFSKEDTENFLIDMDFLG
IENVMALRGDAVKSETYYKPNKNGNIYAQDLVEQIIDLNNGTYLDEDLQNSAKTDFCIGV
AGYPEKHLEAPSLESDIHFLKKKLEAGACYVVTQMFFDNQKYFDFVDKCRAAGITKPIIP
GLKPLATKKQLNLIPQRFSVDVPDALVMEVVNAKDAAAIRQVGIEWCIQQSKELKAAGVP
VLHYYSMGKSDNIRQIAAAVF
>A0A537CWC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
TQYFFNADSYYHFVDGAVAAGIEAPIVPGIMPILSFSKLARFSDACGAEIPRWIRRKLES
FGDDTASIRAFGLDVVTDLCDDLLAHGAPGLHFYTLNQASLTTIIWQRLGLS
>R6CTC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:530|TrEMBL
MKVADFIESGKNPTFSFEILPPLKGNSIQKVYNVVDKLREFDPKYINITSHHSETIYKTL
PDGTLRKENVRKRPGTVAVAAAIQYKYGIQAVPHIICKGFTKEETEYALLDLNFLGINNL
LLLRGDSKGLDIPKEKLSLYNEYASDLQAQVNRFNDGVALDGSKLEGIETPFSYGMACYP
EKHEEAPNMETDLYYAKEKVRNGADYLVTQMFFDNSKYYAFVDRCRAEGINVPIIPGIKP
VVLKNQLTVLPRVFRSDIPEPFASELYKCKTDEEAKEVGVEWCIAQCKDLIAHGVKGLHF
YTFLASDSVRRVAKEVF
>T5KBS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia MF89|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIAFI
RAEHGDAFHIEVGAYPETHPQASDSLADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQG
>J9VRV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)|TrEMBL
MKITEKLQKAEKEGRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALKEAKSHGCQNILALRGDPVAGTST
WEPTPGGFMNAVDLVRYIHKHYPGDFCVAVAGFPQGHPETPDTPEGRAQEMEWLKAKVDA
GAEFIFTQMFYDTSIFFDWVKRVREAGINAPIIPGIMPIQNWEKFEKWVQRENIIVPSHF
YEALNPVRGDDEKVRQVGTKLVADMCKTILANKEAGIKGLHIYTLNLEKGARMLLQELGF
EGRREQIAPLPWRPSLTPSRREETIRPIFWANRTRSYLSRTADWDEFPNGRWGDSRSPAY
GDLDGYPVSIGITAPDAYNLWGHPTTSFDLHALFARFCRGDLAKLPWSTRPPASETSLII
EQLAKMNELGYLTINSQPAVDGVRSDDKVHGWGPAGGYVYQKAYLEFFVSPDLLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWAHLYPADSPSRKLITDTMNTSYLVNIVANDFRDGMSIFEPFLLDQTAVGKVVEGV
KGTVEGIVEGVKGVVGA
>A0A2U1RUZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MESQRNRTKLFSFEFFPPKTPEGEEKLRKARAQLAQLEPAFMSCTFGAGGSTQEGTLKTI
LEIHREGHVAAPHISCIGSKRESIAALLDRYREAGIRRLVCLRGDLPSGMAVAGEFRYAA
DLVGFVRAHTGDWFHVEVAAYPEFHPQARRPADDLAHFKAKIDAGANSAITQYFYNADAY
AHFVESVEALGVDVPIVPGIMPINNFTQLARFSDACGAEIPRWIRLRLESFGDDTASIKA
FGLDVVTELCDRLLGLGAPGLHFYTLNQAGPTTTIWQRLGL
>A0A239QSK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruaniaceae bacterium KH17|TrEMBL
MDVVQSVREGRGGFLLFGITPPKAATPPDRLSQITEANLDRLRAANADGIALYDIAEEQD
RNPDARPFPFLPTHDPGEYLAHHLRDWHKSTVIYRAVGKYSEPELAQWLQNADADQVMTV
LVGASSSSNQGSTSLRRAYELRQELRPDLVTGAILIPERHTNRGDEHLRMLGKQESGAQF
FVSQILYDSNAAKDVLAAYADECEARGITPVPVVFTLSVCGSLKTLDFLEWLGVKVPGWM
RRDLRRAESTLAASLELSRSIAVDMVQYGRRLGVPVGLNVESVSSRRVEIDAAVALSLVL
RGTLAD
>A0A8D9L9T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus eutactus|TrEMBL
MKIRDLITQDKATLSFEVFPPKKDTDFADVEAAALGIAAFKPDYMSVTYGAGGSTKGHTI
QLAQEIQEKYDVPTIAHLTCVCASKEGIKTALADMKNAGIENILALRGDIPKNYDGQVFA
EFSHASELVELIKETGDFCVGGACYPEVHPDSANKHEDIIGLKKKVDAGCDYLTTQMFFD
NNIFFNFMYRIREAGISVPIIPGIMPITRRVQVKNAVKLSGCNVPERFKSIVDAFGDTEA
AMRQAGIAYATDQIIDLMANGVKHIHVYSMNKPEVAAGIQKNLSEILKI
>A0A2W4CLA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium tubonense|TrEMBL
MPSNSEDHRRDIRISFEFFPPKSEEMEAQLWSAVAELEKWEPEFVSVTYGAGGSTKAPTL
AAVRRMISETPLATAAHLTCVSATREDTHRVVDEFRAVGVRHFVALRGDPPDGVGSAYQP
QPGGYANAAELVAGLRELGDFEISVSAYPEKHPESRDVKADVEMLKRKADNGADRALTQF
FFDNDIFEAYLERVRAAGISIPVVPGIMPIQNLTQLKRFAGMCGATIPARLDTRFEGLDE
KPVERAKVAADVAAEQIEDLVRRGLNEFHLYTMNRAPLVGSVLECLGLSCGTKAKAAGAA
A
>A0A7J3T8Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aciduliprofundum boonei|TrEMBL
KCFEKKKAKGKTDFFVGAVLTPGRKGEKMVYRKKLESGAQFFVTQLVYDSEIIKKFLEEI
APEVPVLVGTAPITSFRRIKFLKKLGIAGLSDKIIKELKNARNMNERCIEICSEMYTELK
DFATSMGITIGAHIMSINNPEEAGKIIEKIEK
>A0A833G8T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bauldia sp|TrEMBL
MAPSDERHSRTIGDRGNLNVSFEFFPPKTEAMEETLWRSIERLAPLSPAFVSVTYGAGGS
TRERTHATVARILSETPLQPAAHLTCVAATRSEVDEVVRAYAAAGVRHIVALRGDPVAGA
GTRYEPHPGGYVNAADLVAGIRAAGDLEVSVAAYPEKHPESVSLAADIDMLKRKVDAGAT
RAITQFFFDNDVYAAYVE
>A0A7X9R0B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. WB01_FAA12|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2N7VSI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trinickia dabaoshanensis|TrEMBL
MNPIEISFEFFPPKTPDGVEKLRATRAQLALLKPKFVSVTFGAGGSTQQGTLDTVLDMAK
DGIEAAPHLSCIGSSKESLRAILERYRSNGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRAEYGDWFHIEVAAYPEYHPQARSPKHDLENFARKVKAGANAAITQYFYNADAYFRFVD
DARKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDREAIRAFGLDV
VTQLCERLVKEGAPGLHFYTLNAATATKAICERLA
>A0A1F0E362|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium sp. HMSC064B11|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHFTCIGSKKEEIDRVLEDLERNNIENILALRGDYPVDRELEPGD
FNYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVDAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A380EFM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MQESFTHIELPEHAFLSCYPNASLLDIENSEFKYSDNAQYFGQVAQNLIREGVRLIGGCC
GTTPEHIKFIKESIQTLKPVNDKKVIPIPTKALFNPSQNKVRQSLTSKVQERPTVIIELD
TPKHLDTDRFFENIAKLDKANVDAVTLADNSLATVRISNIAAASLIKQYYNIEPLVHITC
RDRNLIGLQSHLLGLSLIGVNEILAITGDPSKVGHLPGATNVYDVNSKGLTELALRFNQG
INTDGDALKKRTHFNIAGAFNPNVRKLYGAVKD
>A0A349H2J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MPQPTLPQYVFKTRGVMMTGKDFLTRLQDGFVAGDGDLSMRLLQLCPGAGRECLALLNLT
QTNEVRKAHVEFIEAGAELITTNTLDANAVVLGRHGKASQVEAINAKGVELAKADARGDV
CVAGAIGPLGLTLDDDWDLDTYRDAYRRQITALLNAGVSVLQFKFFTNLAALRLAIGEAR
TIGGNDVAIIAQAVFNDGGLLDSGQDAAQVAASLIERGADVVGAHCGRGTSGTVNAIKAM
VKAAGKTPLCAYPNAGFPESDRGEMVYLASADYMGQTANLLARLGVRLIGGCCGASAEAV
RAMSMALGTVRARPLDRTATVEVAPYVPTVASFKNGRLLAALPERLPIIAEIDPPPHLLM
ESMFADVRHVAEAGADAISMAENPLASLKVSNVATASLLMQQVSLPMICHVTCRDRNLLG
LQTDLLGAHLLGIHGILAITGDPVPRHGAAGKGVFDVHSPGLVNLLAQLNRGMTSAGKSL
KQETDFSVGVAFNSATRNMEGEIARYEKKLAEGARFVMTQPVFDREHALRILDATRRPGV
KVFLGFFPLISARTALYLHNEVPGIQIPEHVLQRLTSTEDPQKQQQHGEEQAMALIDALL
PDLDGVYLISPHSTNRAAVLSRLIQHIRQAPAHQQDRSPTR
>A0A841KU25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerosolibacter carboniphilus|TrEMBL
MTHSLKTKLMKKQFVVTVEMEPPRGADPWGVYEKIKPLSALVDAVNIADSPMAKMRMSPI
ALAYLVQKELNLETIFHLTCRDRNQLGLQSELLGAHALGVKNILTLTGDKPEQGDHPDAT
GVFDVDAIGLGRIASNLNNGQDMLGNPIEGKTDFFIGAVVNPTSEDLQAELEKLHRKIDS
GVGFFQTQPIFDMVQLEGFLKIADQINVPIIYGLMPLKSAKLAKYLNRQVPGVHVPDRLI
DRLETKGREAGQEIAEELFLEMKKSLSGVHIFPMGDIQLVETLLKENYENVGCKKAI
>A0A6B2VHA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID13666|TrEMBL
MRTLLQRVRYEVLPAGPTEDQVLAHVPRDVVITVTASPVKGLDPTLDLTVRLAGHGYRVV
PHVPARLLRDGAHVAEIADRLRASGVEDVFVPAGDANPSAGAYEGALPVLRQLSELGSPF
RHVGITGYPERHPLIDDDITIQAMWEKRVHATYIVSNLCFDPQVLGEWVGRIRRRGVALP
VHVGVAGPVERTKLLAMATKIGVGESTRFLARHASWFVRLSAPGGYSPERFLTRTAPALT
APSAVVAGLHVFTFNQIAETERWRRAMLERADN
>B0VPR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain SDF)|TrEMBL
MISALPMSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAP
LEASKSYPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQ
PRSRYLESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLG
YDIEALKQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQ
TGHTDRVYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKTLEELWN
SLWQVTTGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWE
NSVVAKALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEF
GDRECIHSVKARLAKAVKQSEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A841KVA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerosolibacter carboniphilus|TrEMBL
MSTRKLSFREALLDPEQMSVTWELVPGRGAREEAQESVAQMAELAARDSRINSITLTDNP
SGKPAILPYPLALEAKELGIETLIHFTCKDKNRNDIESELHALARSGLPNLLVMTGDYTT
EGFGGRPKPVFDLDAVQALRFIRKMNNGFEIPAHKGSKKLQNTDFFAGAVVSPFKSKEAE
LMAQYYKMHKKIAEGAQFIVTQLGYDARKFDELKRYMDWYNLKTPLVGNIFVLSLPVAKM
MNKNLIPGCVVTDKMVADLEAEKAKGNVKEQQLLRSAKLYAIFKGLKYNGVTIAGHGIGY
TDVKHIIEKGEELSANWLDYVAEFDYPQDNGFYFFEKDPVTGLNTNKIVDRSTTGARAKS
TMKDVMFSMVHHLALSEKAPLYPMIKKIAKKIDKSSMKKPFTKMEYWSKSIMLECRFCGD
CVMHELAYTCPMSQCAKHQRNGACGGSRDGWCEVYPEKQKCIYVTMYEKFKNAGKEGTMK
EGYIPPVNWDLYRTSSWLNFFAGRDYNYRKDVEEQEEAKSYAE
>A0A660Q8U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MKRLMKTLGTGGFAITAELTSGRGYSFAPIQKFLEAHKASGGSAIPDGFDFAGITFPQNP
GGISNLDPSDVLAQLAATDLLDGLDYIPHISCKDHNKSALNSMLIGYKQRGVQSVLALTG
DKPVSAKGVFELEAVGLLQMIGRMNRKELLGCKADTLDQAQQIFAGAAVSPFKYSEPSQL
QQYFKMEKKVACGARFLITQVGWDWKKSLELKFYMEEAKLKTPVLGNVYFLTTTNAAPRL
MHGGKLPGCYVSDRLLAKLKSETFEEHLERAAQQVAMYKTLGYAGIDLGGVHDYDTFCTI
LKRASEIGENWIEFQDNLCWPPDNGFYLYDQEGERTELEPGKQTLHQRWFNFMHKTLLDP
DHKGFHGLKKTMELAGAKKNPDGFAARSFFAMERIAKHAAFECEECGDCYLAENFGFCTM
GGCAKGLANAPCGDAKPDGTCGNEEGVVCRGEQIYLAAKAEEGGLARLRKTINNPRKAAL
EHSSSILNYLFGKDHTMKNALITIGEDIHASIPKHSAIMRELHALGEGAYENDSPQLDYV
RALIENQAEAGADYLAINVDAFGESDPQLSVDIMVEYVKLVRKWGGMVPACIDSSDDNVL
IAGLKEWYNTDDPVKPPLVNSIKTYSADRMMPLKKEYDFSFIGLLMSEEAATPGATQSVE
ELVALAKEIFEKAMRHGFEAEEIFFDSTVFPLAIDMPMQPDVPGYTYRAFETMK
>A0A6G7ZY72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomonas sp. HDW16|TrEMBL
MLPISFEFYPPKTDEQRAQLDRSVQKLKTHAPQFMSVTFGAGGSTLSHTPETVQRLRSEH
GVAGVPHITCVGGSREEIRQLLKLYRALGCDRVVALRGDTPSGMVRSGDLRYASELVALI
RAEHGDHFKIEVAAYPETHPQADDAHVDLRNFKTKVDAGADSAITQYFYNTDAYFRFVED
ARALGIDVPIIPGIMPISNFSQLKRFSEACGAEIPRWIGQRMRAYGDDAVSIREFAADFV
AKLCERLVAGGAPALHFYTLNLSKPTLSVLQRLR
>A0A6B2VS51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID13666|TrEMBL
MAPVVNAPTTSNNLRDVLAAGQRTFSFEFFPPKTDAGERVLWDAVRRIEAVGPTFVSVTY
GAGGSSRDRTVDVTRRIATETTLRPVAHLTAVGHTVAELRQIVGRYADAGIRDVLVLRGD
PPGDPRGPWQRHPGGLDHAADLVELVRSIGDFSIGVAAFPERHPRSLNWDDDIRHFVDKC
RAGADYAITQMFFDADDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDATFPP
ALAEQLAAAQDAPATAHRIGVDHATRLAQRLLDAGAPGLHYITLNRSTATLEIHQNTRSA
DAVPHRR
>A0A1Y2PCA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum holothuriorum|TrEMBL
MKVTEHIEKAKETIFSFEILPPLKGQNIQSIFENIDPLMEFNPPFIDVTYHREEYVYKEL
NGGLLKKQVVKKRPGTVGICAAIQNKYQVDAVPHILCGGFTKEDTENFLIDLDFLGIDNV
VALRGDAVKSETYFKAEKEGHRYASELVTQIQDLNEGAYLDEELQNSSETDFCIGVAGYP
EKHMEAPSLDSDIHFLKKKIANGADYIVTQMFFDNQKYFEFVDKCRKEGITVPIIPGLKP
LSTKKQLNLIPHRFHVDLPDALIKEVVKCKDNKEVRQVGIDWCIQQSKELKKAGIPVLHY
YSMGKSDNIQQIAKEVF
>A0A2V5Q0G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIMDIMRGDLPTFSFEFFPPRTPEAAENLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIKAILVRYARSAIGNILALGGDRPRDIPYDKSR
DSFQHAVDLVKFIRRFNESGEHPDSRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALAGIHIPIIAGIMPITSMSGFKRIAELAGGARFPAKVL
RALQRCENDPEMVRRVGVHFALEQCHDLLDNKVAGIHFYTLNRSDATRVIFDSLGIPHRR
SAQAPTV
>A0A4P5RAV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MLSAAAFAIWRPLIAFMIRFIHDIHESCRAAGRPSVSLEFFPTKTPEGETNLLEKTIPAL
MALKPDYCSVTYGAGGSTRDKTIGIVDRIQREHGLTTMMHLTCVNSTKAELASVLAEAKA
RGVKNILALRGDPPAGASEWTATEGGFMYSSQLVALLKEMGGFCIGTAGFPEGHIAQKGG
KVADWGFLCDKIAAGADFVITQLFFDNEDFFRFQEFLTKRGVKVPIMPGILPVSSAKQTK
KFTEMCGAKLPAPFLKRLDEIGDDDVAATQFGIEYATEQCRGLLKAGVTGLHFYTLNKAA
ATTAIVRNLGLAV
>A0A3S1VYG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.003.01.2.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A086A4J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium soli|TrEMBL
MKITDHIKNAKGKTLFSLEVVPPQKGIGIEDLYRNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLVERRITRMRPGTLGICSAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIEN
VMALRGDAMKGHQYFEPTSGGHASAMDLVHQINNLGRGKYLHDEDQVCDEHNKFCIGVAG
YPEKHIEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRYIEFVTKAREMGITIPIIPGI
KPIATKKHLKLLPQVFKIDLPEELINAVENAKNNEAVREIGIEWAISQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>V0SN70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 907672|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2V6MZ31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIADIMREDSPTFSFEFFPPKTPAAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
HLVERIQHTTKLDPIPHVTCVCHNEKEIEDILVRYAKSAIGNILALGGDRPNDIPYDKSR
DSFQHAIDLVKFIRRFNESGAHPDPRGFGVGVAGFPEGHPATPNRLIEMDHFKAKVDAGA
DYIVTQLFFDNRDFFDFRERCALADIHVPIIAGIMPVTSMSGFRRIAELAGGARFPAKLL
RALRRCENDPESVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRVIFDSLGIPRRR
NAQAPTV
>A0A1L9RDK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus wentii DTO 134E9|TrEMBL
MLPFPLIAGRSAIASTIAGFFRPFPPLTPRTTIHQPPIYSSFLAIGTQVTMEKITDKIAA
LPPDSNYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGSTATRSLELAEI
CQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEEYNIHGEDDSN
KDFTYAVDLVRYIRQQHGDYFCLGVAGYPEGHPPENSQEPQDPVHDLPYLVEKTKAGADF
IMTQLTYDLDVYTKYENMLRNHESGVFKTIPIIPGLMPIHSYKILTRVTKLSHVKVPPPI
LQKLEELKHDDDAVKRTGVDIINDIVEGIKKTACPGSRGFHFYTLNLEKTVSFIIERCKL
IPPPLDEETSAVDSGFLEVSLNDVPKRLARRRGSSMNSQPHNRVIVDRLNGVSDVSSKNS
ATHEVPATSAGMPALPPDRNTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGY
GPSLGVQASVARRIWGHPVQREDINTLFRRLVSGDLHMVPWSEGGAEEGSDGLNAETELI
RPELLKLIDGRGWWTLASQPAVNGVRSDDPIFGWGPQREGFVFQKPFVEFFCPDKDYQSI
LKPIFEKHGHDELAWFATNAKGTFESSLPAQTGDFDTIETNPENVNAVTWGVFKGKEIVT
PTIIEEVSFRAWSDEAYRIWEEWRRIYPRGSPTERFLDSTKNDVWLVCVIGQNFGAGTKV
GSQEEANEVKWMWNVLAGKE
>A0A2V6G3M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHISEIIRSDSPTFSFEFFPPKTAEAAETLYHTIRELESYEPNFVSVTYGAGGSTRDLTH
DLVERIQRTTKLEPIPHLTCVCHNEEQIGAILARYARAAIGNILALGGDQPRDLAYDELR
DSFQHAIDLVRFIRRFNESGAHPDRRGFGVGVAGFPEGHPATPNRLVEMDYLKAKVDAGA
DYMVTQLFFDNRDFFDFRERCTLAGIHIPIIAGIMPVTSINGLKRIAELAGGTRFPARLL
RALQRCESDPESVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRIIFDSLGIPRRR
KVPAPAV
>A0A2V6M3M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMQGDSPTFSFEFFPPKTPVAAEILYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQTTTKLDPIPHLTCVCHKEDEIESILIRYAKTCIGNILALGGDPPRGCSYDKSG
DTFQHAIDLVKFIRRFNESGGHPDRRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALAEIHIPIIAGIMPITSMSGFKRIAELAGGTRFPAKLL
RALQRCENDPEMVSRVGVHFASEQCHDLLDNNVAGIHFYTLNRSDATRIIFDTLGIPRRR
NAQAPTV
>A0A1G7F6Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria marina|TrEMBL
MSEDQQLEFEPRLPSYDEPPPGHVSGSRLERVLRSGHFAVTAELNPPDSADPADVFEAAR
PLAEVADAINATDASGANCHMSSIGICALLTRAGHGTIYQISCRDRNRIAIQGDVLGAAA
MGVRNVLCLTGDGVGVGDQPGAKPVFDFDSLSLLRTIRTMRDQGTFLSGRRITSPPRMFL
GAAENPCVEPLDWRPERLAKKVEAGAEFIQTNYIFDVPVFERFMARVRDMGLERRVFILA
GVGPLASARAARWMRSNVPGIHIPDAVIERIEKSAKPAEEGKRLCVELMQQIREIPGVAG
VHVMAYRREHEVSEIVAESGVLKGRVPERSRTPGTD
>A0A1I4ZX81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bizionia echini|TrEMBL
MKVTEHIKQAKGSTQFSFEILPPLKGQNVQSIFNNIDPLMEFNPPFIDVTYHREEYVYKE
LENGLLKKQVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKSDVYFKPEKEGHAYASELVAQIEALNKGQYLDEELLNVSKTDFCIGVGGY
PEKHMEAPSLDRDIQFLKHKIENGATYIVTQMFFDNQKYFDFVDKCRKAGITVPIIPGLK
PIATKKQLNIIPHRFHVDLPESLILEIIKCKTNEQVKQVGIEWCIQQSQVLKQANIPVLH
YYSMGKSDNIKTIASSVF
>A0A1M3QTR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium 40-81|TrEMBL
MKVTDHIKQAKKTLVSFEILPPLKGKTINSIYDHLDPLMEFKPSFINVTYHRAEHIFKKK
ADGNFEKVEIRKRPGTVGICAAIMNHYKVDAVPHLICGGFTIRETEDALIDLYFLGIDNV
LLLRGDAAKNEAFFEPEPEGHRYAIDLLKQTANLNNGIYLEDNIRNGFRTNFCMGVAGYP
EKHFEAPNLATDLSYLKAKVDAGAEYIVTQMFFDNKKFFDFVDNCRANSINVPIIPGLKP
ISSKKQLSVIPRTFNVDIPTDLSIEILKCKTDADVELVGTEWLKQQSVELKKSGVPILHY
YTLGKPKMVENVVKEIV
>A0A2K9H6N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella jejuni|TrEMBL
MDNNITYIKQILNDETGEKHFSFEVLPPLKGSGTASLFRNIDQLKEFNPSFINITTHHSE
FVYHEREDGLLERQSVRRRPGTVAIAAAIQQRYGIPVIPHVICSGATKEDIEYELLDLQF
LGIENLMLLRGDKAREDRFFTPTEGGHSHTTELIEQVNSFNEGIFTDGSTMKHPGKPFVY
GVACYPEKHEEAPNLEQDLRYLKQKQDLGATFAVTQLFYDNEKFYNFVDQARKMGVTIPI
IPGIKPFAKLSQLHVVPKTFHCDIPEELAGLALLCKTDEEARLLGIEWAVRQVKDLYAHG
FNNVHFYTVSAVSSVHEVMKRIVESGLLQQNSK
>A0A2V5XPZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITEIMRGDSPTFSFEFFPPKTPAAAESLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCICHNEEEIEAILLRYVRSAIGNILALGGDRPRDIPYDKSR
DSFQHAVDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYMVTQLFFDNRDFFDFRERCALTGVHIPIIAGIMPITSMSGFKRIAELAGGARFPARLL
RALQRCENDAEGVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRVIFDSLGIPRRR
TAQAPTVQSNDEIRSRVAN
>A0A1B9H8Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kwoniella heveanensis CBS 569|TrEMBL
MKITEKLQKAEKEGRTFWSFEFFPPRTAQGLQNLYDRIERMRNLGPEFIDITWGAGGKNA
DLTNSLVQVCQETIGIETCMHLCCTEMPKEKVEWALQQAKAHGCQNILALRGDPVAGTST
WKPTPGGFMNAVDLVRHIHKYYPGDFCVAVAGFPQGHPETPEGHDAQEQEMKWLKEKVDA
GAEFIFTQMFYDTDIFFDWVKRVRAAGITVPIVPGIMPIQNWEKFEKWVQRENIVVPDHF
YEALRPVKGDDEKVRQVGTKLVAGMCKTILANKEAGIKGLHIYTLNLEKGARMLLQELGF
EGRREQIAPLPWRPSLTPHRRAESIRPIFWANRVQSYLSRTDDWDEFPNGRWGDSRSPAY
GDLDGYPVSININATDAYNLWGHPSTFTEVCDLFARFCRGDLAKLPWSSQPPASETSVID
EQLAKMNELGYLSINSQPAVDGVRSDDKVHGWGPAGGYVYQKAYLEFFVSPELLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWANLYPEASPSRKLITDIMNTSYLVNIVANDFRDGMSIFEPFLLDQQQQQQALSSV
GKVGQVLGDGIQTVVDGVKNAVVGNSNVVNGHTAQAHAEEDVKLTNGVVINGNGH
>A0A0H5LWU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia intermedia|TrEMBL
MSFYHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASPTQLRDIAADYWKSGIRHIVALRGD
LPPDSGKPEMYASDLVTLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A1Q4F3P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium 44-15|TrEMBL
MKVTAHINQAKSTLVSFEILPPLKGKTINSIYDHLDPLMEFKPSFINVTYHRAEHIFKKK
ADSSFEKVEVRKRPGTVGICAAIMNHYKVDAVPHLICGGFTIRETEDALIDLYFLGIDNV
LVLRGDAAKNETFFEPEPEGHRYAIDLLKQTVNLNNGIYLEEDIRNGFRTNFCAGVAGYP
EKHFESPNLATDLQVVKAKVDAGAEYIVTQMFFDNDKYFSFVQNCRDLGITIPIIPGLKP
ISSKKQLSVIPRTFHVDIPTALSNEITRCKTDADVELVGTEWLKQQSLELKKAGVPVLHY
YTLGKPRIIENVVKAVL
>A0A2E1CST3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kordiimonas sp|TrEMBL
MRPSLFAAKAKGISASFEFFPPQTEKMEQTLWDSIRSLESLQPSFVSVTYGAGGSTRERT
HSTVTRILKETSLTPAAHLTCVAATRDEVDEVARQYWDEGVRHIVALRGDMPELGAAYQP
HPGGYENAAALVEGLKKIGDFDISVAAYPECHPDSSDVNADIDNLKRKIDAGANRAITQY
FFDVDVYFRFMDRVLAAGIDVPIVPGIMPVTNFKQAKKFSASCGTSVPDWLEDLFAGLDD
HPNTRQMVAATVAAEQCMRLYQGGVKEFHFYTLNRAALTYTICHILGIRPPAA
>A0A2V6MGA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
GAMLKERFGITPLLHLSCRDKNVLGLQSELLGMAALGMRHVLPLTGDPARVGDHPGASSV
YDVNSIELISIIGKLNEGFSHAGKSLKARTQFVIGCTFNPNAKNLDSQVNRLERKVAAGA
QFAMTQPVFDVRLVEET
>A0A7I9VDB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia spumicola|TrEMBL
MSERKETTASAHRGQSVVERLAAPHSGPVPFSVEFFPPRDEAAEARLWRAVRVFERMNPA
FVSMTYGAGGSTRDRTVRIAGELATETTLLTVAHLTAVNHSVDELRALVGAYADKGIVNL
LALRGDPPGDPLGEWIKHPEGVEYASELVELIGSLGEFNTGVAAFPEGHHRSPDLDADTA
NLVRKLRAGAEYSVTQMFFDVEDYFRLRDRVVAADAEQGAKPLIPGLMPITSLASARRMT
ELSGSTIPADVEKRLVAAAGDGPEEDKAAIREVGIDLCAEMAQRLIDDGAPCLHFCSLNF
TKATSEVLERIGVDTRGALVGA
>A0A6P4IEY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila kikkawai|TrEMBL
MAHCTPASSGSNPLAYVPCVTFAPEQHVVKEQRIGPLIAEQQAQQRLFYGLEIMPRSRGQ
PVCLDFNRFLPVLPIFVSLVWLGPNYWDVEPIDQVDSLQLAMHLASKIPVMPHLTLYRLN
DERLDQFLDLNFRNVLALRGDSVYSGQKYTISKSIVERAKRRSGDTISICVGGFPEGYNN
ITEGVEPDLTSHIQFLKEKISAGVDCIITQVCYRPEAIIRFVRQVRAAGITVPIMVGIMT
HQSFTKYTFMENLTGAKLSPDLRQELVQIQSESDLTKRFFIRLNVHIIRSILEADLNVFG
FQIFTMNNFEAVEALLKELHLQKLFGNKETELGNSN
>A0A7G8FXP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. PROS-7-1|TrEMBL
MSSALQRSLEAGSITITAEVMPPRGGDPAHTIAMAECLRGRVHAINVTDGSRAVMRMCGL
AVCRLLIDVGLEPVLQMAGRDRNRIAIQGDLLGAHALGIRNVLCLTGDPVRAGDQSSVRS
VHELESVRLLQQVSAFNRGEDPVKEKLADGPINLFAGAAADPHCASWSGLSRRLARKREA
GARFVQTQMVMDPRALERFCRDLADPLELPVLAGVFLLKSARNARFINRMVPGACIPDHL
ITRLDQADDPMAEGIAIAAEQVRQFTGIAQGVHLMAVKAEQRIPEVLERAGVSLPVL
>A0A1F8I3L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacterales bacterium RIFCSPHIGHO2_01_FULL_70_19|TrEMBL
MTGSALSLSEARTLLLSPLGPVARAGQDASRPRISFEFFPPKSEESEASLWQAVSRLAPL
RPEFVSVTYGAGGSTRERTHRTVQRILAETDLAPAAHVTCVEANRSDVDAVIDAYREAGV
RHVVALRGDPPGAAGIGGAYVPRADGYANATELTAAIARRGDFEISVGCYPEGHPESPSI
DHDIEVLKAKVDAGATRAISQFFFDIDAFLRFRDRVRAAGVTIPLIPGIMPVSNFAGLRR
MCGACGTSLPDWLAAHFEGLDEDPETRKLIAASVAAEICARLQEEGFADFHFYTLNRADL
VYAICRVLGVRETKATV
>A0A1V4SLU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminiclostridium hungatei|TrEMBL
MIKNIYDQKKTVFSLEVFPPKNDVDIPAIYEALDQFKQLNLDFISITYGAGGGTRKRTLD
IASYVQNRCNMDALAHLTCVSLDEELLSKLTEEFGKNNINNILALRGDRPKDMPDSVYLS
RPYKYASHLVSLLRANPHMCVGGACYPEIHPESGSQEADLHYLKAKVEAGTDFLITQLFF
DNTRFYRFFEKIRSTGISVPVSAGIMPITSINQIKTIVELSGANIPQDLSEIFVKYEDSP
EDFKKAGIEYAARQISQLLSYGVQGVHLYTLNKVDVSTAIFENLGLL
>A0A2A9EE57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavimobilis soli|TrEMBL
MSIADIVDSSVRPTVSFELMPPRNPDAAPKFWTTVRQLLTARPDFMSVTYGAAGTDRATT
RAVVTTLARQTPVLPIAHLTCVGATRPHVAEVIDEFLASGVRSFLALRGDPPRDQPDWRP
PSDGVHSSIELVALLREVEANRCDRSAASALRGAARPLTIAVATFPGGNRAAGTTPAQEV
EHLLAKQEAGASFAITQLFYEADTYLSFVESARAAGVTIPILAGVLPTTDPARLRRVEEL
TGVPAPSALVRELESLPDDEARHRRGIEASAGLVSAVLEAGAPGLHIYTFNKSRPALDLL
EGVHLGGGSTGPAPAGLAEPDLASGPWVGAAHAQLSSTSDTVAVD
>A0A4P8YFE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jejubacter calystegiae|TrEMBL
MSFFHAHQREALNQSLAELHGEINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDACRDELRTIARDYWENGIRHIVALRGD
LPEGNGRPEMYAADLVALLKEVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNYKQLQKFATLTNVRVPKWMDSMFD
GLDNDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAA
>H0IZC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. GFAJ-1|TrEMBL
MSSQEHPLGISFEFFPPNTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTRDIVR
SVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRAETGDHFEIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVEKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSDAIAAF
GTDVVSRLCERLLDGGAPGLHFYTLNQAAPVLKVVDNLS
>A0A415ZM76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. AM05-1|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTNSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>A0A1A5ZVP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kwoniella dejecticola CBS 10117|TrEMBL
MPQLISLLNDRTTPFHTFEFFPPRTEAGLVNLLDRIQRLASAPLPSPLTVSVTWGAGGST
ADKSLELAEQIVKLGLKVILHLTCTNMPKEKVDQALEKCKSLGVRNILALRGDAPRSEEY
STDPNPQPDYFQHADDLVRYIRKNYDDYFCIGVAGYPTPHPDSETAEKDLEYLKIKCDAG
ADFIVTQLFYDVEGFLEWVKICRRKGITQPIIPGIMPIQNFASFRRLVNLTKCPVPETIS
SDLLPISSDDSAVKRYGAELATKMVKQILESQLVPGIHFCTLNLEKSVRTILENLHWTNS
NVPSINKSPLIRHNRLIEDDQPQTNGAIAINGHTTANGLGSGHQISDLSVSPSEASQLAQ
WGLQHHSLPPVPKKGGIQGGATSNSGQGAEDSWDEYPNGRFTDVRSPAYGEIDGWGSGLK
ITAAQALKEWGTPTTVQELSAFFTSYLRASPETPTTPFCDLPLSPESQTILPHLLELNSE
KMKCWTVGSQPCVDAIKSEDPIHGWGPRGGYVFQKAFVEFFVKEEEVQKLKEKVELKGQG
KISMYAGNKSGSFRTNTEEDTVNAVTWGVFPGQEIVQSTIIETESFLAWKEEAFDIWTEW
SLLYPRHSPARKLLESIAGEWWLVSLIHHDYKDKEALWRFLLDE
>A0A3G6TXT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium balustinum|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICSAIQHKYGVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTLGGHASAMDLVNQINNLGRGKYLHDDEQICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVTKAREMGITVPIIPGI
KPIATKKHLKLLPQVFKIDLPEDLINAVEGAKNNEAVKQIGIEWAISQCQELLDFQVPVL
HFYSMGKSDNIKKVAGELF
>A0A496T3B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MAKSFREHLEQDEVLVCDGAMGTMLYSKGIYINRCFDELNLSNPAMVKDVHLDYLKSGAD
IIETNTFGANWFKLEPHGLEERLYEINFQGVKIAREAAGGKAFVAGSIGPLGRPIEPIGH
LSQEEARQAFYDQAKAQFEGGVDLFILETFKDINEIHQALLAVKDVCDLPVIAQMAFTDE
GKTAYGVSPEEVVRKLEGWGADVVGINCSTGPEGVWKAIQEMARVSDIPLSAQPNAGFPQ
LVQGRLLYLASPEYFAEYAKRFIQSGVRIVGGCCGTTPAHIRAIRTAVKALRPSRQLVEV
KVVEVEEKVLQVKKPAEKSKLGEKLGKKFVVSIEMNPPRGPDFSKVVEGARRIKVAGVDA
VNIPDGPRASARMSPLALATILESKVGIETILHYTCRDRNILGMQSDLLGAHALGLRNIL
IVTGDPPKLGDYPTATAVFDVDSIGLVRIANNLNNGTDLAGNPIGAATSFHIGVGANPGA
ISFEEEISRLKQKIEAGAEYILTQPVFDIKLLEKLLDGIKEYKIPVLAGILPLVSYRNAE
FLHNEVPGMSIPKTVRDRMQRADSGEEAKKVGVQIAQEVLQEVKNMVQGVYLMPPFGRYE
VALQVVEVLK
>A0A2E7QJ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MAVAHPLPKTMNVSFEFFPPNSEKMEQTLWQSVGRLAPLSPSFVSVTYGAGGSTRERTHT
IVNRIQNETGLTAAAHLTCIAASRDEVDEVARQYWANGVRHIVALRGDQPEGDAVYRPHP
DGYAYASDLVAGLKSVADFDISVAAYPEVHPEAKSADDDLDNLKRKIDAGANRAITQFFF
EAETFLRFRDKAAVAGITQPILPGILPVTNFQQVKKFSALCGASVPEWMEALFNGLDDDP
GTRKLIAATVAAEHCRSLQAEGVSDLHFYTLNRADLAYAICHILGLRPSTGAQSKAGNN
>A0A352GGA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MPKPPTDTLRQVAAFGRAAVAGGSVAAPLPDDVEVSFEFFPPSSEGAEANLWNSIQRLAP
LNPKYVSVTYGAGGSTRERTHATVKRLLGETDLLPAAHLTCVDATTQEIDTVAQDYWDMG
VRHIVALRGDPQDTSGHYTPHAGGYSFACDLVAGLRQIGDFNISVGAYPEVHPEARSAKA
DMDNLKRKIDAGADQAITQYFFDTDVYLRFVDQARAAGIWVPIIPGIMPIHNFTKVANFS
KRCGATIPRWLGDLFDGLENDPDTHKLVAASLVAEQCRTLHAFGDKQFHFYTLNQADLTY
AICHMLGVRPKHPVGSDAGDQANKKQAG
>A0A5S9X752|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabidopsis thaliana|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFDCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIGENGLASNEAYQSDLEYLK
KKIDAGADLIVTQLFYDTDIFLKFVSDCRQIGINCPIVPGIMPINNYRGFLRMTGFCKTK
IPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKMLAHGVKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGNLKSSPWSELDGLQPE
TRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLD
AVVEKCKALPSITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWK
DEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIFAVFADL
>A0A6N8XZV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MADNRGRRQGRPGRRRRDAGMTETAMNEAATAGGLKSGGKLERVLAAGGFAVTCETSPTA
TTDLAPLLERVAPLHGVADAVNVTDGATAKAHVSSLVLAGAMMQQGIQPVLQFTVRDRNL
IALQGDILGAGALGIPNILCLTGDDPKKGEEPDASPVFDLDSAGLMRLARRMRDEGVLNA
GREIKGPPRLLIGCADAPMVPKPGWEPKSLRAKIDAGADFAQTQYCFDLETAKAYFGRLA
DFGITERLAFLVGIGPLASLRQAKWMDENLFGVSIPEPILKRLESADDEREEGKKICAEL
IQQLREVPGVRGVHLMAPRQEAAMAEVIERSGVLNGRPAFSA
>A0A2E6C9P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MDISFEFFPPNSSEANKKLWSSIKLLEPLNPKFVSVTYGAGGSTRERTHDCVSKILRETS
LIPAAHLTCVSATKDETEKIIEDYKYVGVKHIVALRGDMPDMKKFRPHPEGYKSSIELIT
RLKKDNFDIIVSAYPEKHPDAESLDTDINFLKKKIDAGASSAITQFCFEIDHLLSFRDKL
EKADINIPIIPGIIPSTNFSGIKKMANKCGASIPIWLEEAYEGLENNLEERKKISEEIAI
DFSINLKKNGFEFLHFYTLNQSELALSVCKKLNIGYL
>A0A2V4DMM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apis|TrEMBL
MKTNLLFNQKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMLKILHDLKCAGIDNVLALRGDISPNVPPKDDF
RFASELVTFIKENGDFNVIGACYPEGHLEATTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKAHDMDINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKSA
>A0A2E9Y5Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MRAMTDRKSSGSLERVLSEGGFAITAETTPPLTADSAKVARRTAPLTGLVHAVNVTDGAG
AKAHLSSFAAAHFMQAENGLEAVMQFTTRDRNKLALERDLLGVSGFAIPNILCLSGDPLE
NGDEPDASAVHDMDASGLVQLATAMRDQGKLPSGREIKPAPRYFVGVADTPIDPTPDWQP
TRLLSKLETGADFAQTQFCFDCEILGRYIARLKEFDIPSRLPMLIGLAPLASARQARWMR
DNLFGTIIPDALIARLEAAGDPAAEGRRICVELIHALKAMPGVAGVHLMGHQAEAQIAET
LREGGFGA
>A0A0F4ZI79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thielaviopsis punctulata|TrEMBL
MHINDKIAEAERTGEPSFSFEYFPPKTAQGVQNLYERIERMNELGPQFIDITWGAGGRIA
ELTCDMVLQAQTIFGVETCMHLTCTDMGNVKIDDALSKAYKAGCGNILALRGDPPREKEN
WEPTDEQFRYAKDLVSYIRQKYGNHFSIGVAGYPEGCDDNKDEDLLLMHLKEKVDAGASF
IVTQMFYDVDNFLRWVRRVREIGITVPILPGIMPIATYASFLRRAKHMNCTIPADWLAVI
EPVKNDDVAVRERGRALVTEMCRKILASGLIHHLHFYTMNLAQSTRMIIEELNWLPSADR
PIKQALPWRQSLGLGRREEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELD
AYGIGLPGTSEQNRAKYGEPQSVYDIAQLFVRYLKKDLETLPWSESPLTGESNVIREKLI
DLNGRGLITINSQPAVSGVKSSDPVHGWGPKGGYVYQKAYLELLVHPDVYPKLIERIEKN
PDMTYYSVTNTGELKTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGKD
WAHCYEAGSPSRQLIDNIMDNWHLVNIVNNDFHENDAIFDLFDGLVVPGVNDIVPSSPSA
SAHSVQDADETKEKSISLSTHITATSTVSNSVPGAAAANGTQ
>A0A1Y5SSF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pacificibacter marinus|TrEMBL
MTKTPNISFEFFPPKNMAATFGLFETVNALHDLKPGFVSVTYGAGGTTRTLTHEAVELLH
KKFGLNVAAHLTCVDATKAETLAIADAYHAAGVSEIVALRGDPPKGAGGFTPHPDGFANS
IELIEALSETGKFKLRVGAYPDPHPEAADENADVKFLKRKFDAGADSAITQFFFDPDTFF
RFRDRAEAAGITGKILPGILPIGSWNGVKKFAQSCGTPVPTHLDDLYAKAGADAEQLSIN
LATDMCEKLIAGGVEDLHFYTLNKPHLSKAVCENLGVTGA
>A0A0V0RJ30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella nelsoni|TrEMBL
MNSSYNLQVKLKSPAYQRAVTVAKVGNPSQQNDFGVYFEEDSFLSLMASLEAVQLKATRH
DLNSAAKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTTEGLINLLKRVDIFANSQP
LFVDVTWVMRSDPASEKVTSSSSLADCILNFCLLDTMLHITSVQYDEKTVLFNLERAKKI
GIRNILALRGDISDDAHVTTTDFQYACQLVRFIRSHYGDYFTICVADAGADFIITQLFFN
EMHYFKFVSDCRKIGIVVPIIPGILPILSYQSIMKIVQLSKIVIPDSVLTTLESIKENAE
AVRNFGISFAVQLCRKLLNREYHVVPGLHFYTLNQEKSILEQLGFWKKAPVRMFPWKKHT
VHSLRCREAVRPIYWTGRPKSYLCRTRDWKQFPHSRWGDVGNPTFGDLKHYLFSCIDQMD
DSCALDMWDKELSTLEHVRDIFCNFIARTPNRHGHSVRRLPWNENHLDPAADILKNELIY
YNSNGILTINCQAAVNGLPSSDPIFGWGEANGYIYQKGYLEFFASSTCTTILLNHVQNFP
SINYHAINFDGSFETFNYDEDATVALTWGVFVGQEIVQPTVASAASFRVWKDEAFDLWQR
WAGLYESGSIGRKLLQKIHDDYRLITLIDNDYPQPCSLSALLRAVISDYWGKKLDDG
>A0A2E8R1S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MKDDQAAAPVSGGKLEAVLKAGQFALTAETAPPDSADATAVLARTGCLKGLADAVNVLDG
PGAQTHLSPLAAAAILEADGIEPVLQFTMRDRNRLALQADILGAGALGIHNILCLTGDSP
EAGDQPKTKPVFDLNSAQFMETVRDMRDASHYPGGRRIETPPRLFIGGADAPRKLDDDFT
PGTLEAKIAAGADFFQTQYCFDMDTLRDYLARISDFGILEKTHFIIGIGPIASARSARWM
NENLFGVNIPEEIVTRLEQAEDSKAEGRKVCVELIQRMREIEGVSGAHLMAPHGEEAAAQ
VIRECGVLEDRAA
>A0A1U9MI87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bartonella apis|TrEMBL
MPAPSLSRRPDLGDKLKVSFEFFPPKTEKMEEMLWQTVERLAPLKPDFVSVTYGAGGSTR
ERTGRTVERIIKETHLNAAAHLTCVDATREEVDSVARQFAAMGIRHFVALRGDPSNGIGG
RYHPTPGGYANAVELVAGLKAINPDFEITVSAYPEKHPESPDFATDIDLLKRKIDNGATK
AITQCFFDNHFYEDYIEKVRKAGIYIPILPGILPIHNFWQVKNFCARNGTHIPDWLAQRF
EGLENDQKTHDLVAAAVAAEQVLELVEHGVEDFHFYTLNRADLVYAICYLIGIRPKQQTA
NNK
>A0A1Y1V083|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piromyces finnis|TrEMBL
MKIIKKIEKAIQQKRTFCSFEYFPPKTPQGVNNLYDRFERMALLGPEFIDVTWNAGGVTS
DLTIEICSNAQTVYGLETNMHLTCTNMPVEKIDHALREAKKAGVQNIFALRGDPPRGVKD
WTQCENGFAFAIDLIRYIKKGYGDFFGIGVAGYPEVHPDSPSKEDDLKFLKEKVDAGADF
IISQYFYDVDLFLQWVKDCRDAGINCPILPGLLPIQTYDKFINMIRMNNTSVPEYILKDL
EPIKEDDQAVKDYGIKLLTEMSKKLIANGIPGIHIYTMNLERSARVILENLGLAQSQEIV
KPLPWNRSLKNNRLKEDVRPIFWRNRIKSYIQRTDSWDEFPNGRWGDSRSPAYGEINLHS
SSSFKYSNADCLAMWGNPEKPEEVFEVFSKYLKGEIKALPWCETALHKESSIIRERLINI
NKKGFLSINSQPSVNGAPSTDKVYGWGPKNGFVFQKAYLEFFIKEEKLQKLEEAIKEDGF
LSYYAINQKGDLKTNQKDETANAVTWGVFPGREILQPTIVELVSFLAWKDEAFTLWNIWK
DLYDKNSKSYEIINELSTNYYLINIVDNNFQRVDKIYDILEKL
>A0A2D6FVL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MDGWSIEATLPKKSEVENLAELVPAGTEVFLSTLPHVSLDQQIETAHIVRVNGFEPVLHV
AARYFASRTELVGYLARANRETHADNMLIIGGDAERPKGEFGSALSLIESGLLADYGIHR
IGIAGYPDGHPKISDQRLDHALDEKIEAAREAGMQAHIVTQFCFNAGPITAWLSEVRGRW
PEIDIKIGLAGPTGLKTLLKFAMRCGVKAPLNGIGQKLTLASQLAKSFSPGALIDELDAN
LIDTNDARNLSIHFFSFGGLEKTAGWVAERLAEYTATSATA
>A0A3D5UVX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MTKTQKKEREERTRVSFEFFPPKTPEMEETLWKSIRRLEPLQPEFVSVTYGAGGSTRERT
HQTVKRIHDETSLEPV
>A0A412HSM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF23-3LB|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAHEVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A428RBH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium floridanum|TrEMBL
MDRITDRIAALPADGSYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRREE
YRDPDDSEDDGGQDFNWAADLVKYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVEAGADFIMTQLFFDIKAYEHFENTLRDHPSGAFKTLPIIPGLMPIQSYQMIKRT
TKLSHAQIPEDILTRLNAVKGDDEKVKMVGVDIVSELVEKVKDIKSKTPGPKGFHFYTLN
LEKAVSFILERTNLIPEPPEDEEALVVDDAIPIPALQVNGSSNLRSGSHSRSRASRRHSS
VGSDPHNRVIVGDRPATHPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDF
PNGRFGDARSPAYGEIDGYGVSLHMSITQAVKFWGHPKTRQDINDLFVKHIQGELSAIPW
SEEELLAESSTIQPHLLRLNQKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEF
FIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVSSDKGGHVDGSSEAGPSTNAVTWGV
FPGKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSDSEKLLSGIKDEYWLVNLIHH
DFVEKDALWQVLSS
>A0A5C7NNB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MNKAVTFSIEVFPPRDAAGWDQFDQALARLGKLQPRFCSVTYGAGGSARQGSDIALAHVR
RRNSLTPAAHLTCVALSRGETLEIARHWWAEGIRHIVALRGDMAEPGTPFHPHPAGYGNA
AELVAALHELAGFEISVGCYPEIHPDSRDRLADLVNLKRKLNAGATRAISQFFFEPEVFL
RFRDAAAAIGIDHPLVPGILPILDFNKAAGFARRCCASVPGWLIDRFDGLENDPDARGQV
AASLAVSMCERLIAEGVQSFHFYTLNRPTLTLAICHALGIQPALERAA
>A0A367EW49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerisporangium album|TrEMBL
MTDHAFQIVCEIEPPTRPDLMHVRHQIGTLSKVADTFLVPDNHIGRATVSSVAVAHEVGA
MGGRSIACLNARDRNLLGFRRDLLTAAAYGVDRFLFVYGDKPAAGGRTGELSVRAMIDEV
RGLPDDPAFAGIAPFQAGAAAGLRTLPAWKRSADFLFVQVSYSLEALLRWREANPVDVPV
YAGVMVLASEAHARRLAAAIPDIDIPDDLVRKVAADRLAGVEATCEHILAIRDSGAFDGV
HLVPVSRYREVAARLEPLLA
>A0A3C2DXI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTNVSHHAPTPPVAPPQRDGIKVSFEFFPPKTEKMEQTLWAAIKRLEPLAPQFVSVTYGA
AGSTRKRTHATVVRIRRETNLEPAAHLTCVGADRDEIDAIARRYWKEGICHIVALRGDQP
EQEDTYTPHPGGYAYASDLVAGLKKIADFEISVAAYPEIHPESQSVQDDLDNLKRKIDAG
ASRAITQYFFDVDVFFRFLDRAAAAGIEVPIVPGILPVTNFARVTEFCRACGTSVPPWMA
SMFEGLDNDSETRRLVAATIAAEQCQILQARGIKEFHFYTLNRADLAYAICHILGLRPQE
GVGGAAAETTAHGATGAADGGAE
>A0A2I0SJ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces populi|TrEMBL
MALGSASTRTDRARTVRDMLATGKQTFSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVLDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSTEWDLDVSHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCGTPVIPEVMPVTSVKMLERLPKLSNASF
PDVLKERILTVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A2I0STP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces populi|TrEMBL
MDAEGLGVLLSGVRYEVLPAKATVDQVLAHVPRDVVVTVTASPVKGLEPTLGLVGRLAAH
GYRVVPHVPARLLRDDTHLKDVVDRLRETGVDDVFVPAGDADPPAGAFDGALPVLRRLSE
LGGPFARVGITGYPESHPLIHDDLTIQAMWDKRAHATYIVSNLCFDPRVLGDWVGRIRRR
GVVLPVHVGVAGPVQRAKLLAMAAKIGVGESTRFLTRHASWFLRFATPGGYAPDRLLARG
AKALTAPSAEVAGLHVFTFNQIAETERWRRALLARSGD
>A0A1T1HLJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MF6394|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMTTAKQLASFSPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2E1TVB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTDTKAAVMKLFGDFTVETTPNSAAKIPDYNARLRNDTPIYVTFLPGSDVYETVTLAKRL
RGEGFSPIPHIAARSIQSEDMLRDILDRYVGEAGVEHVLTIAGGVDNPLGPFDSSMAVLE
SGLIDKAGIRRVSVAGHPEGSPDITDELIKDALAWKNGFAERTGAALDIVTQFAFEAEPI
IAWDQRINAEGNRLPIRIGLPGLATIKTLLGFSRAAGVGNSIKFLVKRAADVTKLMSINA
PDKQVIDLARYAAEDPKAGISGVHMYAIGGLKRTSAWSYALRDGLFEVTGKDQLKVSVDL
G
>A0A419S142|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pseudopneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A374W2K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. OM06-18AC|TrEMBL
MRVDEVFKQAASQGTTPISFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENILALRGDLPAGAT
EDDKPASDYAYARELIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A8C1UHE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVQDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCECDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGAHFIVTQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNCRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQEEGTF
>A0A7C5AIL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MREKPGMQANLSEALKAGSFALTLELVPDEKGASRTADIAQSFAAAAAEAGRTIHAFSLT
DNAGGRQGASADAAALELLRRGLCPLVHVTCRDANRLAIMSRIRGLRDAEVRHFFIVTGD
YPADSPQGRPAAVFDLDSVQAIRLAKSVAPDIFAGAAVSPFKETEAELMGQFFKMERKAA
AGADFIICQLGYEMRRFLEAKAYLEARRLDIPLLGNIFVPTSASARAMNFGRVPGCVFPD
DLLLEFEKAAAAPDKGRSFRLELAASMLAVFQGAGFSGAHIGGFGLKPADLSHLLARAAE
IGRNWPEALEHLSR
>A0A7X7IY69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MAQQNRQLDMSFDGDQRLAEAFKLGHFITLLEVTTPAASQPIDSAAAVLQPLLKQASALD
EINGITLSDRLPDGQRHDPAEFAQILLSSFDKSAVLTISGKGSSLDRAKTICAAAHGRGL
RNVLAVTGDLPTQAADTTPAPPTPRPFLDSAEALRALYDFNRQLCLGAVVNPYKYTAQDQ
CLQYAKMLRKLRSGATFLVAQAGWDMKKSQELQWFMQMREMHEPIIARVIMFSREEALRL
GEWRQPGITLPVPLAAQIMREATLQPSDYITAQIHRCALQIIGYRVLGYSGVQIAGCRDP
KTLALLAAHCRELTAT
>A0A6N2S507|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium innocuum|TrEMBL
MNNAEFLKEAGVDAVTIADCPIARARVDSSLLACKLHRELALDIIPHMTCRDRNINATKA
LLFGLQIEGISNVLVVTGDPIPSEDRQEVKGVFNFNSQILAGYIRDLNETMFSNPFMVFG
ALNLNAVNFEAELAKAKRKAEQGMEGFLTQPVHSQQALINLKRARTALNAYLLGGVLPIV
SHRNAVYMNNEISGIEVDEEIVARYEGTSREEAQRLAVTISCQTIDAMRAYVDGYYLITP
FNRVEIIAELISHIHAH
>A0A8C1WAK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGKDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIITQLFFRAETFLKF
VKDCRAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPQETQEEGILWI
>A0A2V3J337|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gracilariopsis chorda|TrEMBL
MTVTANGTAKPFSIGSDPNLRQLPKIADKIRQRQSENRPFFSFEYFPPKTETGVCNLYQR
VERMTAIEPLFCDVTWGAGGSTSDLTLDLSGNIQKYLGVDVMMHLTCTNMPAGKVLEGLE
GAKNRGIRNILALRGDPPAGKEWTKCEDGFEHGTDLVRFIRANYGDYFGICVAGYPEGHP
AGFLEGKITYDKEMEYLKEKVDAGADFIITQMFYDVDTFLSFVRRCRDIGITVPILPGIL
PIQNYTGFKRMTGFCRTFVPQSILDAMEPIKDDDVAVKEFGIRLGIDMCRRILKSQLCPG
IHFYTLNLENSVMGIIDNLNLIPRTESIRSLPWRPATIDKRRNENVRPIFWANRPKSYLD
RTSTWDDFPNGRWSDNRSPAFGDLTDYHLLGGGGWASATRKADAAKRYGDIKDFDDVTDV
FTRFQKGELKRLPWAETEELATETSVISAPLLWLNRNGLLTINSQPRVNAAPSSDVTVGW
GSAGGYVYQKAYVEFFAKPEIVDALFEAAGHFPSLTIYATKANSDKLRTTAKHKSTCAVT
WGVFPDREIVQPTIVDPDSFLVWKNEAFNVWTNVWADLYNEGSPSRAVLNELKDSLYLVN
VVDNDYVGGDIFGIFKMVLAQSV
>A0A0F2L290|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum thiophilum|TrEMBL
MTAPISAPPSVSFEFFPPKSEKMEQSLWQSIRRLAPLAPGFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGQYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDVYFRFLDRCAAAGIHVPVVPGILPITNFARAVEFAGKCGASMPAKLAETFEGLDA
DPETRQLVAATVAAEQCQALQAQGVNDFHFYTLNRSDLTIAICRMLGVKAKPVPAAVAAP
AVAG
>A0A1R0XFB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus odorifer|TrEMBL
MTPPKASHAPEKVSEIARKQVERLKNLDLDALILYDVQEEVDRVDHERPYPYLPTIDPAV
YGDKYLRQVEVPKIIYRCVGNDTRAQFEDWVKADENEDRFSVYVGASSSKQEVKLNLPEA
YKLSKQLNNNLTFGGVVIPERHIKKNDEHIRVVEKTNNGCNFFITQATYNVEASKNLLSD
LYYYYTNNGFEMVPILFNLAPCGTAKTLQFMKWLGISIPGWLENELKYSNDILDKSIQLS
QKIFEELLDFGLEKGIPIGCSIESVSTSKLEIEASVQLVKDVKGILDKKLPSHESNIKQS
IM
>A0A2D6AW36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flammeovirgaceae bacterium|TrEMBL
MKVTEHIKAAEGKTLFSLEIIPPKKGDSIDSLFNHIDPLMEFKPPFIDVTYHREEYVYKN
RGNGLLEKKTIRKRPGTVGICAAIKNRYNVDPVPHIICGGFTKEETENALIDLNFLGIDN
VLVLRGDSIAEEKTFKPEPDGNAYAIDLVDQVVGMNEGQYLDEDLQNAVPTTFCIGVAGY
PEKHFEAPNLTSDLKYLKQKIDHGAEYIVTQMFFDNQKYFEFVDKCREAGINVPIIPGLK
PITAKSHMTILPSIFHIDIPDELYTEIEKCKDNKQVKEVGIEWGIKQSKELMAAGVPVLH
YYSMGKSDSVERIAKSLF
>A0A1R4FDL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas diminuta 3F5N|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRSAVNVSFEFFPPKSDVAEANLWKAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVHRIISETTLRPAAHLTCVEASRADVDEVIEGYKAIGVDH
IVALRGDPPGSTGIGGAYTPRADGYANATELTAAIGRVGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLKRMT
AACGAALPDWLAAHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAVA
>A0A4R5CHF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium cellulosilyticum|TrEMBL
MKVTQHIEDAKGKPLFSFEIVPPQKGSNIKDLYANIDPLMEFKPPFIDVTTSREEYVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGVDAIPHVLCGGFTKEETEYLLVDCHYLGIDNL
VALRGDPMKGEKYFEPMKGGNNYAVDLVKQIKAMNSGRFLHETLPMQSAPDFCIGVAGYP
EKHIEAPSLEADLKRLKEKVVAGADYVVTQMFFDNQRYFRFVEAARAIGITVPIIPGIKP
VAVKRHLQLLPQVFWLDMPESLITSIEQAKDNIEVRQIGVDFAVQQSKELIEFGVPCVHY
YSMGKSDNIYNIASRVF
>A0A373GE90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AF32-8BH|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEIAKIIY
>A0A1I6UGW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halolactibacillus miurensis|TrEMBL
MKTSELFQHKKVLSFEIFPPKQTENLAAIYQTVNALKELAPDFISVTFGALGTKNNQRTL
DIASTVKHTYGVESVAHLPSSQFTKRDVQALLTRFKQLGIDNILALRGDDITEHKEKKDF
HYASDLIEYIKSEGDFNIIGACYPEGHIESVSILDDVRHLKEKVDSGCDQLISQLFFDND
YFYTFKERTELIGIDVPIQAGIMPVVNKRQIEKMVKMCGVNVPKKFLKMMERYEYHPEAM
RDAGIAYAIDQIVDLITQGADGIHLYTMNNPYIAHRIYQAVNQLLIAS
>S7XEK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis 18/56|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISSLQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A7C1F8K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MRFRDRLCSGRFVVTMDSIPPKGTDLSRTLRALAPARERVDAINVPDMPSAVMRVSALAV
ARALKEQGFEPILQMTCRDRNRLALQADLLGAAVLGIENVLILGGDDVSLSDHPGARGVF
DLDSVALLEAARSLERGVDMAGHRLEGAPRFCLGAAANPNAASPDDELREMEAKVRAGAD
FFQTQPVFDLDAFAAFMKRAEGLGVPVLGGVFLLKSARMARYMNENVPEVHVPQWVIAAL
EGAKDPAAKSLEIALSILQGMRGLCAGVHLMTVNWEAQAIALLEAAGL
>A0A6A4L448|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhododendron williamsianum|TrEMBL
MKVIEKIREAESGGKVVFSFEFFPPKTEDGVDNLFDRMERMVAHNPTFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVDKIDHALHHIKSNGIQNVLALRGDPPHGQDK
FVQVQGGFACALDLVNHIRSTYGDYFGITVAGYPEAHPDVIQSDGGLATPEAYQSDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFIPSEITAALEPIKDNEEAVRAYGIHLGTEMCRKII
ANGIKTLHLYTLNMEKSALAILMNLGLIEEAKISRSLPWRRPTNVFRVKEDVRPIFWANR
PKSYISRTIGWEQYPQGRWGDSRNASYGALTDYQFVCGPSLILFDGIEIMLHLHMWEGGA
EDVKLVFMRARTRGRKLHDEWAVPLKDVEDIHERFLKYCLGNLRSSPWSELDGLQPETQI
INEQLGSINSKGFLTINSQPSVNGAKSDSPIVGWGGPDGYVYQKAYVEFFCSKEKLNTLV
EKCKSFPFLTYMAVNKEGSWISNVRSQSDVNAVTWGVFPAKEIIQPTVVDPTSFMVWKDE
AFEIWSRGWAQLYPDGDPSRKLLEQVQSSYFLVNLVENDYVNGDLFAVFRDF
>A0A7X9B0H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oligosphaeraceae bacterium|TrEMBL
MKKKNISELIREQLLIFDGAMGTELYKRHVFTNRSYDEICLSDPKLVMEVHMDYLRAGAD
VLTSNSYGANRSVLQKFGLADQVEAINSKAVELMRSSIERLSPERPIYLAGSIGPLEPGL
QQKMSREEAVQVLVEQAEVLAESGVDFLIFETMPDREAAMQASLAMAKLTQIVPFVLSHA
LPDGEDLPGILAHRLQPMQNDLPIPFALGLNCGLGPARMLEALEAARKLTELPIIVQPNA
GTPRKVENRQLYLCSPEYLSTYAQRYVNLGARGVGGCCGTSPEHISELARSLKRLSQSFS
SITVSASAKQEVVTAKETALAERSQLGRKLANGEWIKTVEITPPRGWNTERIVNNAKLCR
QHGVDAINIPDGPRAAPRLSALVTALKIQQEAGIEAVLHVCSRDRNYLALQADLLGGAAF
GLRNFLFITGDPPKLGGYGYASGVFDTDSIGLVALQKHLNQGVDLGGQQIQPPTAAVIGV
GADPNAIDFNREIERLKAKIDAGAEFIITQPVFDIEPFHKFMQVIEDWKVPVIAGVWPLA
SLRNALFMKNEVPGVLVPDSVVARIEKAQTREEQLACGIQIAREAIEQLRGMVAGVQVSA
PLGNVNAALAVME
>A0A8D4VVM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomagnum ishizawai|TrEMBL
MRSQQHYPQAYSLEFFPPKTPEAETSLNNALAKLAPLRPKFCSVTFGAAGSTREKTFETV
VGLQTTYGLEAAPHISCVASTRDNMREVLNAYQNQGIRHIVALRGDMPSGMMSAGEFRYA
NELVAFIRQETGDHFHIEVAAYPEMHPQAQGIEADLKNFKRKVEAGADSAITQYFFNPEA
YFRFIDDCEKLGLDLPITPGIMPITNYTQIARFSEMCGADIPRWVRKRLEALGDDRAAIR
AFGLEVVSDLCRRLLEQGAPGLHFYTLNQAEAVLGIWKNLGLESA
>A0A2U2SMW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPIFTPGRRWQPPFYPFKKEPFGARLLAGIEKMVKGPLFGCRMCGNCLLQETAFICPMEC
PKGIRNGPCGGSTPEHCYVDETRPCIWYKIYERAFRMGREEYLLEVLPPLDWNKVGTETW
GDVVNQVRKIGTKNVVTGLLSKDPVKRTVTWDSVFRPVRQPEWWQGDAEYHPPKYTEPIS
ELERRLKAGEFVVTSEVAPPMTVSTNKLLQNIELIKPYVTAINFTDSPSATPRMSSWACS
VMAVQAGAEPVMQIAARDRTRVGLQSEVLGANALGVRNILCLSGDSMRMAPDPRGRMDVV
DIDSVQMIWILRRMRDEGKYLDGRAIKFPPKIFIGAAASPYASEPRFQAIREHKKVNAGA
QFFQTNLVYDLDGLEIWLNELAKRNILDKVYILVGITPLKSYKVAQYMHNEVPGVFIPER
LMKRMEKAGDGASEEGVQIALELIEGVKKLQGVHGIHLMAVGWEEIVPRIVREAGLAPKE
MQQAETKSTEALLNS
>A0A7V8QFD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodospiraceae bacterium WFHF3C12|TrEMBL
MTSQSTVAETVDAWTPEFALTALAAGASLEIPASAHASEAPALRQLPADTRVYLPHTPRT
TVDETLAACRTIIAAGLRPVPHVAARAVPGEDWLGELLDRLQAAGTDELLLIAGDRKKPA
GPYGDTLQLLDSGILLRHGFRRVGVAGHPEGHAAANDEAAMAALEAKAAYARQTGSEVWI
ATQFVFEAEPVLAWLQRLQAAGIDLPVWVGIPGAGKLRTLWRYALHCGVGSSTRMLTRRP
DVALALGGGWRPDELVGELARQYATGMARPMAGIHLFPFGGVGPGIDWLTGLRNGQGLPE
TLGVEAPAEY
>A0A7C4ZU41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MRTGSRLERVLRSGRFAVTAELNAPDSADPNDVYKNALVLAEVCDAINATDGSGANCHMS
SMGCCALLTRAGYEAVLQISCRDRNRIAIQGDILGAAAMGVKNILCLTGDDVSNGDQPQA
KRVFDFDSIQLLRVARIMRDQGVFLSGRKLTTPPKLFLGAAENPFVPPLDWRPLRLGKKV
EAGADFIQTQYCFDVPRMQQFMQRVRDLGLHERVFILAGVGPIRNEKVAEFMRTKVPGVW
IPDAIVDRLTKTPKEQKVEEGMRICIEIIQQVREIEGVHGVHVMAYRQEEMVAEIIKRAG
LLPRRARRELPRATSTEILVPETPPV
>A0A0K1Q691|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labilithrix luteola|TrEMBL
MASFLEALAAGPLVVDGAAGTQLYERGVLYSTCFEELCVSKPELVKKMHEDYVRAGAQVL
ETNTFGANAMRLEKHGMTSRVREINLAAVKLAREAAAGKAFVAGAIGPSGYFLGNALPED
LAKVRSALSEQAQALVEAGVDVLLIETMRQTNELRIAVESAVAASGGKIPVIASASVDEA
SRMADGTSSGEIARLMREWGANVVGVNCCDGPMNVLEAIEPMLELGVPVWAVPNAGLPRR
VDERLVYVSTAEYFGVYARRMFKMGVKLVGGCCGTTPEHIKRIAAAARMVGSSEAKSAPP
DSEVVRASDSFQTWSAHPPAMPGAAKATPFSERSDFASKIARGKFVVSVEVNPPVGLDLS
KAITAAKMLKEGGVDVVNIADGARAQARMGNVAMAARVQQNVDMETILHVCGRDRNLLGT
IAHLLAAHELGVRNLVVVTGDPPKMGDFPDASAVYDLDSIGILKLAARLNHGIDPGGKPL
GCGTRFVLATGAEPAALNYDRELSRLRQKKDAGAELVMTQPVYDPAVLDRFLTDIAPLGL
PVLVGLLPLASYRNAEFLHNEVPGMQVPEGVRERMRKAGTGAAARKEGVAIAREMLAAVR
GRVAGAYIMPPLERYELALEVVDGFLDRDDRPAASANA
>A0A7Y5BH36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospiraceae bacterium|TrEMBL
MKKISDILKQSNTCLFSFEFFPPKTNEGEIKFFQTLKEISKLNPAFVSVTYGAGGSTKEK
TIELSEKINKENMFPAMCHFTCVSVNSEQIEKTLHEINSKGISNLMALRGDPPAGEGIFQ
KTTGGFSNATELIQFIKEKKFNFSIAGGCYPEKHPETKTMEEEIFFLSKKVEAGAEFLIT
QLFFSNPVFEKYRELAIRSNVEVPIIPGIMPITDFKQIERFKKMTGCNIPENFVSRLEKF
KENPDDFLKVSLDFTTHQCLELMKSGVKGLHFYTLNQSKTSYEIVKNLT
>A0A7C4Z6U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
PLSSSTDKLIRNIELVKNLVTAVNFTDNQSATPRMTSWACSQVAMNRGAEPVLQMSARNR
SRGSVQSEIIGATALGVRNVLCVTGDSAKMSPSPRDQMDINDLDAIQMLWVLRRMRDEGK
YLDGREIKNPPMFFLGAAASPFSSNVKFQALREQKKVNAGAQFFQTNLIFDVDGMENWLN
ELAKRNVLDKVFILAGVTPIKSLKMAQKLADVPGVYLPKEILHRIEVADRAGNAQEEGIQ
IALEIIGKIRGFEKQGIHGVHLMPVGWDEVIPRIVTESGLAPKHILFDNTARELIHAHDL
EK
>A0A831TKR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermorudis peleae|TrEMBL
MAHPFLERLSRGPILCDGAMGTQLYERGVPLDACFDEVNLSNPSLVVEIHRDYILAGAEI
IETNSFGANRFKLEPHGFSHLVRQINRQAARNAREAREITGQPVLIAGSIGPTGRTLAPI
GTTPPEVVRDAYREQISALLEGGVDLLIIETIFQLEEMRQAVLAAWDVCDLPIVAQMTFA
SDGRTIHGHTPEEVIHTLMELGVTVAGVNCSVGPRPTLEVLKHMLSESGGAIPLAGQPNA
GWPRHLGNRVIFTASPDYFADYAREAITLGVSVVGGCCGTTPAHIQAMRKALDVLEIPDI
RRPAVIEVRTRRPRELLAAEGPTRLAQKLGKEFVVSVEIDPPKGLNPHKALAGAQLLKGA
GVEFINVADSPMARVRMSALALCALIQQHVEVETILHFTTRDRNLMGLQSDLIGAHALGV
RNIIALTGDPPTLGNYPQATAVYDVDSIGLVKIIKQFNQGMDAGGASIGQMASFTVAVAC
DPTRPNLDEEIERLHRKIEAGADLVMTQPVFALSVWTDFLRSYEERYGPIPVPVLLGILP
LQSHRHAEFLHNEVPGITLTEEARERMRLAGPDGRREGVRMAQELLLEAREAVHGIYIMP
SFGRYEVAAEVLEILPDRRLLAAVPGGQPS
>A0A7V2XFK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSRLQQELEAGKFVVTGEIGPPKGIDTHEMEHELEHLRGKVVAVNVTDIQSAVMRLGSLI
VSEWLVRQGVEPVFQLTCRDRNRLALQTELLSAAWVGIENVLCLTGDHQVLGDHKGARGV
FDLDSVSLLHTVRTLMSGKDLAGNELAGAPKFFPGAVVAPGLEPMEPQVLKFENKVAAGA
RFFQTQAIYDPRQLEAFMRRVEHLKVPVLAGIVLLKNAGMAKFMNANVAGVFVPDHLIKE
MADCPKKKLKQKSAEIGGRLAKEMKGMCQGIHLMPLGWTDIVPDVLGHAGLI
>A0A0Q5WC39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter sp. Leaf380|TrEMBL
MTPSVDVDLQHATRACPKSMTYGPCGGVGDDGTCEVAPVPCSFLPLPTVRWSGARESRTV
PEPHLLALMRQRPVVVADLPAVALSRDSLERAADRVVGAVDAVLLGDHGAARVQFSPSYR
ASLVQARGVPVWQGLNCRDRNRVALEGELAGLADLGVGAVHCVTGDHTLTGDRPDAQPVF
DLDSTALAAAAKAAGVLVSVGETPHGPPAQRRAERLREKVRAGADVCFVNHAGSVEALRA
FVEEAGDLGVDVPFVACVAVATDPGSAAQLRRFTSLRLPAGYLAGIESAPDPRRAGIAAA
IALAQAYLSVPGVRGVDLSGVPTAGAELTTAAALAEIGCALT
>A0A1Q6G0A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. 58_9_plus|TrEMBL
MNVLDIINTAIAEHRTRFAFELLPPLKGDGMGGVFAAIDRLIGFDPAYINVTFHREGIKQ
SVRPDGGIDWHVVRRRPGTVGISAAIQKKYGVEVVPHLICGGQSKYDIEDALIDLDFLGL
HNVLALRGDKSQNEKFFMPHPQGHSHAVDLVRQIAAMNRGEFVDGEVEECHHSKFSIGVA
GYPEGHEESPSPEADIAALKAKIDAGAGYIVTQLFYDNARFFDFVRRCREAGIAVPIIPG
IKPLSTLRHLTLLPQTFGCRIPEELEREVLRHREDPKAIREVGTEWAVAQSRELKQAGVP
VLHYYPMGKADNIIKIAKAIF
>A0A542HK01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SLBN-115|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFYAPKTPKGERSLWNALRRVEAAAPDFVSV
TYGAGGSTRATTVRETQQIVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDTDVTHFVD
KCRAGADYAITQMFFEPESYLRLRDRVEAAGCVTPVIPEVLPVTSVKMLESLPKLSNAHF
PAALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A3D4EW68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
FPEGHPETQNRLTEMNYFKSKIDQGADYICTQLFFDNHDFFDYRERCNLVGIDLPIVAGI
MPITTISSMKRMADLAAGSRFPAKLLKRLSVADGD
>A0A1H7GI62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colwellia chukchiensis|TrEMBL
MKNGSELRARYNDVNRGVYFIGTTPPKSDTPIAQVSAIADKLLERVSDIDFDGLIVYDIQ
DEDSRTSKPRPFPFKSTHDPRLYSSLLNEKSKRPVITYKSVVQSNNADFNQWANDAWHKY
GVRDIVLVGSPSNKNTISLPLGDAYQALVANDNDFFIGGITIAERHANKRNEHAKLIEKH
QQGCNFFISQAIYNAQATIDMLTRYAIECQQQGIKPQRIILTFSPCGSEKTLEFIEWLGV
SVPEATSLRILNAKHPLYESIRICTNTLVQILDAVLPYQLPLGLNIESLTNRKEEIDGSI
LLYKLLRSTMDNYLAKQELGALANQD
>A0A522YJL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIEHINQSQGTLISFEILPPLKGKGIGAIYQHLDPLMEFNPSYINVTYHRSEHIFRKK
ADGSFEKIVVRKRPGTEAICASIMNRYNVDTVPHLICGGFNIQDTEDALLTLSYLGIDNV
LVLRGDAEKNETSFEPEPGGHKYAIDLLQQVVNLNHGTYLEEELKGNNGTTFCIGVAGYP
EKHFEA
>A0A4P5XEE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MKIASLFQRPSPVVSFEFFPPKTEEGVETLYRTVEELQSCRPSFVSVTYGAGGSTRGRTI
ELVSRIQRDLGIATMAHLTCVGSTRADIRETLLQLEGGGIQNVLALRGDPPKGETEFRPV
PGGFRFASELVAFIREQGFDLCVGAACYPENHVETKDANADLANLVNKVQQGVDFLISQL
FFDNDDFRAFVRRARSAGIAVPIVPGLMPVTNFAQTQRFTQMCGARIPQELHRRLAIVEK
DPAAVVATGVHWTAQQAQDLLRTGAPGLHFYTLNKSSATLAVHAALGI
>A0A3M2FI86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium|TrEMBL
MKWSDIYAQTDGPLISCEFFPPKTDKGEQNLWRCLNDLKAIKPAYVSVTYGAGGSTQDRT
QRIVTRIKDETGLSPIAHLTCVGSTQQQLRALLDAYRAAGIENILALRGDPPEGMSRFEV
VQGGFAHATDLIDFIRAQNGFCIGCATYPEGHPESPNGVADDIRYLKMKQDLGAEYAITQ
YFFDNERYFRFLDQAEKQGVHIPVIPGIMPITNFDQIERFSAMCGATIPDWLRNRMQPIR
GDLDEVKRLGIEIATRQCQQLLDAGVAGLHFYTLNKAEATIAIVNALTR
>A0A4Q1AKF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp. CECT 8989|TrEMBL
MLTDKIRNKENGILLYGITPPKVKHTEEEIKEIAKKHVERISSLNVDGLVLYDIQDESDR
TDEKRPFPFIKTINPCEYSKNYLQDLKTPRIVYRAVGNYTAKQFATWLESTKATQVHSVF
VGAASHEQQTNITLKEAYGIKKEVNDNLCLGGIAIPERHMKKHDEHLRVFSKQNSSCEYF
ITQCVYDVHAAKTFLTDYAKYAKENNIEPVPIIFTLTPCGSSKTLDFMKWLGINIPNYLE
EDLKESGDILSDSVKLSRDIFEDLFKYGKKRGIPVGCNIESVAIRKAEIDASVELLEEIR
QIIKDNK
>A0A4Q3V3Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
PEPGGHRYAIDLLKQVCNLNSGVYLEADLKNSAKTKFCIGVAGYPEKHFEAPNMDSDLQY
LKMKVDGGADYIVTQMFFDNEKYFSFVKACRNMGITVPIIPGLKPVYTRKQLNVLPKTFH
IDIPTELSTEMNKCQSDESVAQLGAEWLLHQSKQLKAAGVPVLHYYTIGRPELVADVVRK
LV
>A0A4Q3V853|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MTDSQPRLSFEFFPPKTSEGKEKLIKVRDQLNEFEPDFFSVTYGAGGSTRDNTKGVVSQF
KNDGINIAPHLSFGSDDKETVLKLLNEYKFLGVDRIVALRGDVPSGMGGQQQLVYANELV
AFIRQHFGNAFHLEVAAYPEIHPQAKSYADDIRYLKGKFDAGAGLWYESPKFYAGISANN
LFRSVYT
>A0A3M2BMP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MHIQDIYKQTHTTFSFEFFPPRDATAAGELFENIRELEQLRPTFVSVTYGAGGSTRELTR
NLVVRIREETTLDPVPHLTCVCQSERDIARILERYAEHGISNILALRGDPPQGVSNYDPD
ADTFRYASELVSFIRRFNESGAHPDRRGFGIGVAGFPEGHHQTPNRLLEIEYLKAKVDQG
ADFIITQLFFDNRDFYDFRDRCRLAGIKIPIIAGVMPITSMAGMKRMAELALGARYPAPL
LRALARTDGRAENVRRVGVHWATEQCRDLLDHDVAGIHLYTLNKSTATREIYRTLGVQDS
RALQQ
>A0A4Q5WVK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTEHLEAAQGRTLISFEILPPLKGKGINALWEHLDPLMAYKPAFINVTYHRSETMFKR
KADGTFDKVEVRKRPGTVGICAALQNRYAVDAVAHLICGGFSKQETEDALIDLNFLGIDN
VLVLRGDAPKNEATFEPEPGGHKYAIDLLEQVQRMNSGLYLEEDLKNAVKTNFCIGVAGY
PEKHFEAPNLKTDLQYLKAKVDAGACYVTTQMFFDNKKYFEYVEACRAAGINVPIIPGLK
PLTTRKQLSIIPRTFHVDIPEELSEAVLRCKTDADVELVGTEWMLMQSKELKAAGVPVLH
YYTLGKPHVVANVVKELV
>A0A356KY82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MASYARRFVKAGVRLVGGCCGTTPAHIRAMKEAVVAARPAARPPRLDAPRDESVELNTPE
RGAKSVLGQRLAERAFPVCVQIRSPKGCDPRPTLEHVRELHEAGVDLVSVFEGRGGARMS
AFALAQIIQREVGTETLLEIASRHRTLLRMQATVLGAHALGLHNLVAVTGPPLTLGEYPD
ATKDFEVDSIGLSNMIRRLNEGRDVAGQSIGTPTAIHLGVHLDPFAVDTEYEVRRFEWKV
DAGAEYALTPPVVDAKALVEFLPRIAHCRIPILATIPLIGRFRDVERLRQFGAGRAPQAL
LDRMMRAEREGREREEGLAIAVETARALREHVEGLQVVAQTARLSDVPPIVEAV
>A0A4Q5UYG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIDHINQSTKPLVSFEILPPLKGKGIQSLYNHLDPLMEFNPAFINVTYHRSEHVFKKK
TDGTFEKVVVRKRPGTESICAAIMNKYNVDTVPHLICGGFGINETEDALINLNYLGIDNV
LVLRGDAAKNEASFEPEPGGHKYALDLLKQVTNLNSGVYLEEELKNTTKTKFCIGVAGYP
EKHFEAPNMDTDLQYLKQKVDAGADYIVTQMFFDNSKYFAFVNACRSIGIEVPIIPGLKP
IYSKKQLTVLPKIFHIDLPTDLSNEIVKCKDDEAVEQVGTEWLLMQSKELYKAGVPVLHY
YTLGRPNLVASVVKDLV
>A0A358KH33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDIHAKKAAAGKPTISFEFFPFKTPEGEATFFGKTLPALMTARPDYASVTYGAGGS
TREKTLEIVEQIQNDFSLTTMAHLTCIKHTQAEIDAILDEANNRGIRNILALRGDPPPGE
DWSQTEGGFEFASELVTHIRGRGDFGVAVAGFPEGHIDCGEGREVDWQHLVRKVGCGADM
VITQMFFDNADYFQLADFLRGAGVEAPLFPGIIPVANAGQIKKFSAMCGAKLPEAFAARL
DELGDDAEAVREYGIEYATVQCRELLDRGAPGLHFYTLNKSKAVLQILGN
>A0A5C9ERT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAYSKLGEMLEKGEFILTGELEPEKTCDLSHTIHEAEEMAPYVVAANVTDSPLGIVTINS
MAASHIIQRETGLEVIWQLTVRDVNKLGIAGMIMGGHALGIRNVLSLTGDHPAMGDIPET
KPVFDLDSATLCKLVREMVDEGKINGAEIECPPTLHVGAAANPNADPMGAEVLKIGRKAK
AGAEFIQTQVVYDLDRTIEFLREIKKYNVPVLLGIFPMKSYGIAKGFDEFVPGVSVPKDI
LAKWKSIKKEISDKKEQKKAYDQANYEFFNPFITELRKKDLLEGIHCMAVHYPRIFPKLQ
KVIDDTS
>A0A7I7VDZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium fallax|TrEMBL
MVDRIAEIAVARTPFSVEFFPPRDEAGEAQLWRAARAFEPLDPAFVSVTYGAGGTTRDRT
ARIVGELAATTSLLPVAHLTAVGHSVAELRELIDHFAAVGVHNVLALRGDPQGGVRQEWV
QHPEGLAYAVELVELITAAGGFHVGVASFPEGHPRAINLAADTANLVNKLRAGAEYSISQ
MFFDVEDFLRLRDRVCAADPEQGAKPLIPGLMPITSLRSVSRMVELMDSQIPTSVLERLS
RAAGDGPAENRDAVRRAGIELATEMSRRLIDEGVPCLHFCTLNFAKATSEVLTNLGLTQS
RVGSGAVTRGD
>A0A6G2N6G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4945|TrEMBL
MASGTASTWTSEHPTVAEVLASGKRSYSFEFWAPKTPKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRTGTVRATQAIAENTTLVPVAHLTAVEHSVAELRHMIGQYADGGVRNILAVR
GDPPGDPLGDWVAREDGLTYAAELVRLIKESGNFCVGVAAFPDMHPRSENWDSDVRYFVD
KCRAGADYAITQMFFDPASYLRLRDRLSAAGCETPVIPEVMPVTSVRQLERLSRLSTAVF
PKTVKERMLAAKDDPAAVRSLGIEFATEFCARLLAEDVPGLHFITLNNSTATLEIHENLG
LPHHRP
>A0A524EY45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MESNHAYSKLGEALAKGDFILTGELEPEKTCDLSHLVQEAKEMAPYVIAANVTDSPLGIV
TINSLAASYIVQRDAGLEAIWQMTVRDVNKLGIAGMLMGAQALGIHNILSLTGDHPNMGD
MPESKPVFDLDSATLVKLVREMVDTGKINGHEIESPPKIHVGAAANPNAEPMEAEVLKIG
RKAEAGAEFIQTQVVYDLDRTIEFLTAIRKYRVPVLLGIFPMKSYGIAKGFDTFVPGVSV
PKDILGKWKGIKTDLKNDKKLQKEAYDQANYEFFKPFITELRKKNLLDGIHCMAVHYPRI
FPKLEEVIKSTN
>A0A7K4GP47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAKRPAYSNLVKTMREGKFLFTGELEPKKMVDLSSILHSAEEMKKTGKITAANVTDGPQG
DAYTCSLVPCHLVQEKVGLETIWQMTVRDRNRIALFGDILGGSILGLKNLLALTGDHSAL
GDNKNARAVYDLDSTQLIDLVSKMVDDGTDLEGKEIEGGKIEMNVGCAANPNSNPREPEI
LKVGRKVEVGADFVQTQTSFDIDDAKEFLKELEKFNVPVLLGLFPIKNYGIAWYFNEYIP
GVSVPKDLLKALKTVKKDYKEDKKKRNDAIDKINIEFFEPFIKEIQKTTKAAGIHCMAVH
YERLFEPLLKNF
>A0A6M8RBZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus vulgaris|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPQTEEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASREELQHIAQDYWQSGIRHIVALRGD
LPDNTQKPDMYATDLVHLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMFD
GLDNDPETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPELIKA
>M4KQ09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis XF-1|TrEMBL
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKTAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITDKEVKTRAKEFIS
VHHERTEPGLDEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADFFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMAHAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>A0A4V1U4H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MANSQLNLARTSDGVGQRAQREALTRALRGATYEVLPFKGTEDKVLAHVPNNIALTVTTT
ESKGLGPTVDLATRLCRQGYRAAPHLAARLVRDRAHLKDISDQLRDAGVSDVFVIGGDAA
EPVGEFHDALSLLENLEDLDQFDSVGIGGYPEGHGKISDELIEQALEAKAPHAAQMITQL
CFDPETTIKWARLVHSRGVHLPIRVGIPGAISRQKLIRVSAGLGLGQSARFLKKQQNMLW
RFFLPGGYSPNKLVERLTPAFEQNDNALQGFHVFTFNELESTEAWRQAWLGRLS
>A0A0C3HNF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oidiodendron maius Zn|TrEMBL
MEKITEKIAALPPDSNFFSLEFFPPKTAMGSSNLRTRLERMSRALRPLFVTVTWGAGGST
SAKSLELAELCQRELGLTTCLHLTCTNTNKALVDRALEQAKNLGIRNILALRGDPPRSEE
YTVSGDREGQNDEVEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADESDPQGQSLEHDL
PYLVDKTRAGADFIMTQLFFDVEAYDKFEKRLREHESGAFKTIPIIPGMMPIQSYQMIKR
TTKLSHARLPPEIMSRLDEVKGNDEMVKKVGVDIVSEIVEHLKIPQVASPSRRGFHFYTL
NLEKAVSFILERTHLITPILSRSSSAIIEIVPTSLHDLPVNGTSEHKKSNRRLSSVGSDR
HNRIIITAPETANPDFEATALEASVPAEEISTRANALAISEGEGALGREATWDDYPNGRW
GDARSPAYGEIDGYGVSLHMTFNQAVKLWAYPSSVQDITSLFLRHIEGSLSAIPWSEEGF
NEETNTIKDQLLELNKKGWWTVASQPAVNGVRSSDLVFGWGPRNGFVFQKAFVELFLPSK
DWKVLHAKLTAPGVAEDVGWYASNSKGDFLSGDANSGVDEEAEGTTHAVTWGAFPGKEII
TPTIIEEVSFRAWTEEAFAIWAEWARVYSLRGRPDPEIAERARSSKELIENVMEDVWLVN
VIHHRYIEKDALWSLLLN
>C8X270|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfohalobium retbaense (strain ATCC 49708 / DSM 5692 / JCM 16813 / HR100)|TrEMBL
MRIADLMQPGKKFISLEFFPPKDEGNWPGFFEEVHQLASMDPLFVSVTYGAGGSTQDNTL
RLVSRLKQMGLEPMAHLTCVGASAATLHDFMRSLQASDIDNVLALRGDPPQGQDTFVPDN
ADFQHASDLVRFLREHYPECGIGVAGYPEGHQEAPDFETDLDYLGLKFQTGGDFAITQMF
FDNAMYWRMLDQAQAKGITKPIVPGILPIMHLNTVKRISSLCGATLPPAFLQQLEEAEAE
GGPAAVKDVGIKYATEQVRDLLAGGAPGVHLYTLNKSEACLRIYRELNACLCE
>A0A101B4V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. GA-2829|TrEMBL
MTSTDLRCPKRMQFGPCGGVRPDGQCEMRSGPCAFPDVVPWSGVAPAPRPAQAPLVLTDF
SCAPFDEVDVAATAATLADSCDAVLVGEHQNRPDFPPTLMGRLLLESGVSPWITLSCRDR
NRVVLEQELRGLRTLGVGTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGMVAAV
PETPTAPPVHARPARLVEKQRAGASLAVLNHVPYPAAVADFMAAARAAGLTIPVVAAVAV
FTDVVSAAVLQGLPGLELDQAVVETVLGATDPVAAGIAAAVEEATALLAIEGVEGVNVSG
SATSAGTRAGAEIKAEVGRLIKAQEAA
>A0A023CVY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus sucicola DSM 21376 = JCM 15457|TrEMBL
MNVNHPSLSFEVFPPNTAAGTANIKETLDRLQALNPNFISVTCSNNKSNIEETTLKLAGY
INNTLKVPAIAHLPAAYLNTQQVTRILTELDSLHIHQLLALRGDIIPEVPRKDDFKYASD
LIRFVHAQKPGFKISGACYPEIHPESPDLVSDIRYLKQKVDAGCNQLITQLFFDNDRFFT
FKENCALAGIKVPIIAGIMPITNRKQALRLIKTTSAHLPKKFLAIFDKYEHDPASLRTAG
LAYAVDQIVDLITRGAAGIHLYTMNHAETAINIQNTIGSLFNSSAQLNN
>A0A1H6E747|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces yanglinensis|TrEMBL
MTPAPPAAGTGRDRTFSFEFFPPRTAEGERRLWSALRRIEAVRPDFVSITYGAGGSSRDR
TVELIRRITTETTLRPVAHLTAVGHSLAELRSVIGQYADAGVRDVLALRGDPPGDPAGPW
TPHPRGLTYAHQLVDLVRSLGGFRVGVAAFPERHPRSPDWESEVRHFVAKCRAGADYAIT
QMFFRVEHYLRLRDRVAASGCDIPIIPEIMPATDHQQISRFAALSGASFPPLLAERLLAA
GGDPAAGRRIGVDHASAMAERLLAEGAPGLHYITLNQAEVVTRIHRNVVPDPPALPAATA
VSTATAMPTGPVHVRTLRAAAAAAE
>A0A075P5N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas australica|TrEMBL
MVSYAQGVDALNQSLSELRDIDVSFEFFPPKSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVQKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTSVFLRFRDRAAAAGIDLDLVPGILPVTNYQTLVKFAGFTNVHVPGFLHKMFDGL
DDDDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRGNGTK
>A0A1V5Z2F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium ADurb.Bin170|TrEMBL
MTKFRTFYDTGQPVISFELFPPKTQEGLENLFLHLKELAACKPAYFTCTYGAGGSSRERT
LGVLREIHDTYPQIPLASHLTCVGSSVDELRAFLRQAQEIGITHIVALRGDLPQEDPEYT
PPADGLRYANELVSLIRSEFPAFGISVAGYPETHPEAPSTAADIENLKRKVDAGADFIVT
QIFFDNADYFRFRDRCSDAGITVPIIPGVLPVTNLTQTRRIVNMCGAHLTSKLVKRLEVY
EDDHEGQYAVGVYYAARQAEELIKQGAPGIHFYVLNKSRATVQICRALALFTPVD
>A0A8J6WZV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc muscorum FACHB-395|TrEMBL
MYHTHSHTAFRRAVQAGEFLVTAEVAPPKGGNPAHMIQMAATLKGRVHAVNVTDGSRAVL
RMSSLLASVILSQNGIEPICQIACRDRNRIALQADLMGAHALGIRNILALTGDPVKAGDH
PDAKAVFDLEAVRLLQLIRKMNQGVDYNEKPLTDGALDLFVGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFERLEKFMDTIASGYKKPILAGIFLLKSAKNAQFINRCVPGVN
IPQHIIDRLAKAKEPFEEGIKIAAEQVQIARQLCQGVHLMAVKREDAIAPILDLAGIAPV
NQLVSK
>A0A848Y6T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
VSVAVEQVLDLAAQGVRKFHFFTLNKSDLAVAVCRSLGLAPVQQTLKAA
>A0A8I1TFX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSQPLLSSSDAARIRLSFEFFPPKSEEMAGQLWSTVDELAAWQPEFVSVTYGAGGSTREP
TRSTVERLLRHTSLSTASHLTCVGATREEVAQVVDDFRRIGVRHFVALRGDPPDGAGAAY
RPHPGGYANAAELVAGLRAIDDFEISVSAYPEKHPESADVAADIDMLKRKVDAGATRALT
QFFFDNDQFERYLEKVRAADIRIPVVPGIMPIQNLQQLKRFAGACGAGIPAAIDARLAHL
DADPAARATVAAELAAEQMADLYRRGIHEFHIYTMNRAPLTNRALRMLGLRPASTAAGAA
A
>A0A800J5Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVIEHYERATEPLLSYEIIPPRRGGSVAQVLEIVEALAPYDPPFIDVTSHSAEASYEEM
PDGSIRRQVKRKRPGTLGLCAAIQHRFGIDAVPHVLCRGFTREETEDALIELNYLGIHNV
LAVRGDDTGTPKVERPERTVNDYACDLVGQIAAMNRGEYLDEGLLDATPTDFCIGVGGYP
EKHEEAPNMTWDVLHLKRKVDAGADYVVTQMFFETQHYIDFVERCRDVGITVPIVPGLKI
LTTRRHLRSLPRTFKVEIPESLAAEVEAARDEHIPSIGVEWARQQAEALMDAGAPGIHFY
IMSDPQHVLRVVEPLRA
>A0A848YDX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
AMGVHNMLVLHGDDPKSGDMPEAKGVYDLDSRGVMDLARMMRDEAKLPSGREINPAPDFF
IACADMPMDPKPDWTPNGLEAKIESGAQFAQTQFCFDTGVAERYFACLREHGVTDKLKFV
VGIGPLASAKQARFMDENLFGVTIPDHIIERLDAAEDQKAEGRKICVELMEAYQYIDGIA
GVHIMAPMQGGKAIAETIRMSGLR
>K7Z3F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Endolissoclinum faulkneri L2|TrEMBL
MFNTPNVSFEFFPPKDEEGEANLLHTVSRLEPYRPSFASVTYGAGGSTRERTNRIVKRLV
EESTLTPAAHLTCVGATREEINSIVRTWQAAGIKHIVALRGDAPAGAEKYEPHPNGYANA
AELTAGLRKMGDFEISVGAYPDVHPDSPSAAADLENLKRKIDEGANRAITQYFFEADTFL
RFRDVCTKAGIKVPIVPGILPVVKFKTVLHFSKSCGAVIPQWMADLFDGLDEDPEISQLV
AAATATELCMKLMTEGVEDFHFYTLNRSQLTSAICRRLGRKPNMKDTT
>A0A2D3WE84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurospirillum cavolei|TrEMBL
MVESFIEKLRSDTFLSLETTPMHEPTFEPIIEKIASLKLDQKVDGFSTTDNPLARLKYNA
LMGALKLQHRFHKPVIATMSMRDRNKLALQSDLLGANEHDLRTILCLTGDPAGASDQPQL
KGVFEGNSTLLMEIIQCFNASIDYSGKPFKTPPKPIYPFAVCNAHANTPKHLAKKMATKI
SHGAIGIITQPVYSEENARMLLELFDEAKTLSGKKESPCELILGFFPIVHLRTAQFLSAH
VPGVHVPDMWTEKLLHAKKIGENEEKKVGFELSLQTFQTLRRVHPKTHIMSANHFELIAD
ILNA
>A0A7J5F2A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MHIADVLAQPGPHFSFEFFPPKSEQASTALFDSITELTVLRPSYVSVTYGAGGSTRQLTQ
DLVLRLQRETQLTIVSHLTCVGSSRAELHDILTKYADSGIENIMALRGDPPKGSAGFTPH
PEGFRNAGELVAYIKKHFPSMGVGVAGFPEGHPDTPNRLKEMDHLKAKVDQGADYICTQL
FFDNRDYYDFLERCEIAGIRVPVIAGIMPVSTRKGLAKMAELALGARIPAKLLRAVSRAE
NDEFVEKVGVHWATQQVMELLDHKAAGIHFYTLNRSKQTVKIYESLGVQSSDALRKAPTP
L
>A0A8F4GAQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella sp. PL-2018|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAKDYWDSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFRQAKKFADMTNVRIPTWMAKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A2A3DBT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3860|TrEMBL
MSVRHQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVF
LGAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQTARDLGHTEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>A0A2T4WEM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKITDLLQEVKECQFTFEILPPLKGQKAMEIFDNLDPLMEFKPPFIDVTYHREETIYKRL
DNGLLQEKVVRKRPGTVGICAAIMNRYDTETVPHVLCGGFSREETENLLIDLNFLGIENV
VALRGDQAKHESYFTPHKEGNAFAIDLVHQIKDLNQGKYLDEELQNTTATNFCIGVAGYP
EKHFEAPSLNLDIEYLKAKVEAGADYIVTQLFFDNSKYFAFVEKCRAAGITVPIIPGLKP
LSTKRQLSILPQIFHVDIPDDLAIQAIKCKDNTQVRQLGIDWCIQQSKELRDAGVPVLHY
YSMGKSQNIYEIASAIF
>A0A2T4WNT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKITEHIEKAESTLFSFEILPPLKGQKIEDIYSVIDPLMEFKPPFINVTYHREEVVYKRL
PSGLLEQKVVKKRPGTVGICAALHSHYGVDTVPHILCGGFSKEDTENALIDLDFLGIKNV
LALRGDSMKNETLFAPEADGHTYASDLVKQIKAMNEGRYLEEELQNSNPSNFCIGVAGYP
EKHYEAPSLNNDIENLKAKVDAGADYIITQMFFDNQKYFDFVDRCRAAGINVPIIPGIKP
VATKKHLSFLPHFFKVDMPDDLVKAIINCKTNLEVRQVGIEWGIAQAKELKAAGAPAIHF
YSMGKPDNIEAIAKAVF
>A0A3M1LB32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVIEYFEKAKGQTLVSFEVLPPLKGGSMQAIFDVLDPLMEFKPPFIDVTYHREEYIYKR
RPSGYYEKIAIRKRPGTVGICAAIMHRYGVDAVPHLICGGFTKEETENALIDLNFLNINN
VLAIRGDARKFDGKFVPEPEGHAYAIDLVRQIVDMNHGKYLDDNIENGVRTDFCIGVAGY
PEKHFEAPNMETDLMYTKAKVDAGADYIVTQMFFDNRKYFDYVEACRKIGIEVPIVPGLK
PLTKRYQLNSLPRLFHVDIPTELVREMEKATTPEARQQVGIEWCAMQSRELKEKGVPCIH
YYTMGDSDTIRAVVEKTF
>A0A2Z5MEL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia caledonica|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLALLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHLSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCRRLISAKVPGLHFYTLNGAAATTAICERLGG
>A0A2D4ZUM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKITEYIKQAKGKALFSFEVLPPLKGQNIQTLFDHIDPLMEFKPPFIDVTYHREEYIYKK
RENGLLERKTVRKRPGTVGMCAAIQNHYKVDAVPHIICGGFTKEETENALIDLNFLGIDN
VLVLQGDVRKPDRQFIPEPDGHSYASELLAQVVDLNKGIYLDGEIENAMPSDFCIGVAGY
PEKHETAPNMESDLRYLKKKVDGGADYIVTQMFFDNQKYFDFVNRCREKGITIPIIPGIK
PVTTLKQITLLPQLFNIDLPEALTQELEKCTNNEAARVVGREWTIQQTKELVEFGVPSVH
FYSMGKSTSVYEVAKEIF
>A0A661Z2Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTDHIKQANETLFSFEILPPLKGEHFGHLENNISRLLEYNPAFIDVTYHQQEVEYREL
PDGNLEKKTVRKRPGTVGMSAAIQYKTQKDVVPHIICGGFTKEDTENALIDLHFLGIDNI
LIVRGDPVSNQRYFVPEKEGHSHALGLVKQVSDLNNGKYLDDELLNSHPTHFCIGVAGYP
EKHSEAANFQLDLKNLKDKVDAGADYIVTQMFFDNQKYFDFVDKCRAIGINVPIIPGLKA
LATKRQLQILPQTFHIDLPEELVKEALKCKDNTQVRQLGVEWAIAQSKELKAKGAPVLHY
YTMGKSDNIEKIVSEVF
>A0A5N5W5R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces mobaraensis|TrEMBL
MALGTASTRTDHARTVRDLLASGERSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSVAELRNVIGQYADVGIRNMLALR
GDPPGDPTGEWVRHPQGLHYAVELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFHADDYLRLRDRVHAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PADLAERIRAVEDDPAAVRSIGIEYATELCARLMAEETPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A1E3YJU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. SCN 61-19|TrEMBL
MAHIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMAKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDHVIARLEGAADQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGILKGRRPWKREHARADDIAAERMREIGADPVQDQQTLAGLAA
NTQTH
>T0NU29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Camelus ferus|TrEMBL
MRASEAGSARFSVPPCISRNSAMVNEPRGNGGPNPRSEGSSSGSESSKESSRCSTPGLDP
ERHEKLKEKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRPHEKVANGGAPPGAPLQKEI
PCRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSRE
EITGHLHKAKQLGLKNILALRGGDQWEEEEGGFNYAADLVKHIRGEFGDYFDICVAGYPK
GHPDAESFEADLMHLKEKVAAGADFIITQLFFEADTFFRFFKACSEMGITCPILPGIFPI
QGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCRELLESGLVPGLH
FYTLNREVATMEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGKELTSEESVFEVFVRYL
SGEPNQDGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPILD
WGLGPQWGLCLPEGLAWAYLEFFTSRETTEALLQVLKKYELRVNYHIVDVKGENITNAPE
LQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGKLYEEESPSRMIIQHIH
DNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRAPQNEREMEAP
>H9ZNR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus thermophilus JL-18|TrEMBL
MKIRDLLKARRGPLFSFEFFPPKDPEGEEALFRTLEELKAFRPAFVSITYGAMGSTRERS
VAWAQRIQSLGLNPLAHLTVAGQSRKEVAEVLHRFVESGVENLLALRGDPPKGERVFRPH
PEGFRYAAELVALIRERYGDRVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIEIPILPGIMPVTSYAQLRRFTEVCGASIPGPLLAKLEQHQ
DDPKAVLEIGVEHAVRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGLRSASGQP
>A0A4Z0FAN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Macondimonas diazotrophica|TrEMBL
MGGSQADTALSTLSFEFFPPKTPAGMSKLLDTASRLADLKPAYFSVTFGAGGSTRERTLD
TVLTLMQETGIEVAPHLSCIGATTDGLREILRRYQDAGIRRLVALRGDLPSGMGDPGALR
YARDLVRFIRSETGNHFHIEVAAYPEIHPQAQNARDDLANLCDKVRAGADGAITQYFYNL
DAYTQLIAEVRASELDVPVTPGIMPILNHAQLARFSDSCGAEIPRWIRKRLEGLESDEQA
LRAFGHQVVTDLCRRLLTHGAPGLHFYTLNQAEPTLHICRELQSLTIAN
>A0A4Q3GIR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSEMSGTEPAQGRKLPQISFEFFPPKTEEMERVLWETITRLAPLNPDFVSVTYGAGGSTR
ERTHSTISRILKETSLTPAAHLTCVAAPKSDIDDVVARYHDVGVRHIVALRGDPTTGIGT
QYHAHPDGYQTSAELVASIKKRYPDIDVTVSAYPEKHPESADFDADIDTLKAKVDAGASR
AITQVFFDNDLYHRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRA
>M7CVX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter santoriniensis NKSG1|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQVVRNTLAEVNPDFFSVTFGAGGSTRDRTIETV
LSLHKQGISTAPHLSCVGGTRQEIGELLDLYRENGINRIVALRGDLPSGMGASGELRYAN
ELVTFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVEAGANSAITQYFFNADSY
FYFIERLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCERLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A1T3MH57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia occulta|TrEMBL
MKVTEHIAQSKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGEKYFEPTKGGNRYASDLVTQINDLGKGKFLHGEISGNDLNNSFCIGVAG
YPEKHLEAPSMQYDLKMLKQKVELGADYVVTQMFLDNQKYFEFVKLAREAGIDVPIIPGI
KPLAVKKHLQLLPQVFKIDIPEDLVNAVSQCNNNEAVKQVGVEWCVQQCKELLDFGVPAL
HFYTMGKSDNIQKIVSEFF
>A0A0C3N1N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera sp. SWB20|TrEMBL
MKPEISIEFFPPTTAEGAEKLHATREKLAALEPAFFSVTYGAGGSTRERTFATVKEIAAA
GHEAAPHLSCVGSSRDSIREILQEYAAAGIRRIVALRGDLPSGAGAAGEFRYASELVEFI
RSETGDRFRIEVAAYPEWHPQAKSPKDDLAAFKRKVEAGADSAITQYFYNLDAYLNFVDA
VRRMGVDVPIVPGIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDSDAIRAFGLDVV
TRLCEKLLAAGAPGLHFYSMNMAGPTTEICRRLGLTA
>A0A662AEJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MRVVDQINKSEKTLFSIEIVPPLKGHDINRIYNIVDPLIEYNPSFINVTYHKDEVLYKNL
SDGSIEKRTIRKRPGTVALSAALKNKYNINVVSHLTCGGFTKNETENALIDLSFLGIDNL
FVIRGDAGPNEKSFTPEDGGHAHAIDLVKQIKNMNNGKYLYDELEDSMHTNFSIGVAGYP
EKHAEAPNIETDLEYLKQKVDAGADYIITQMFFDNEKYFQFVEFCRKKGINVPIIPGLKP
IALLNQVNVLPRIFHIELPEALVKEVNKCKSNKEVTQVGIEWTINQSKELIKHNVPVLHY
YTLGAGKGIQKIVKALF
>A0A485NTW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lynx pardinus|TrEMBL
MVIASTAVNYCGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDRVGEQWEEEE
GGFSYAADLVRHIRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQL
FFEADTFFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKD
NDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPW
AVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRW
>A0A485NZW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lynx pardinus|TrEMBL
MVNEPRGDGGPTSRSEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDGTGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDRVGEQWEEEEGGFSYAADLVRH
IRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRW
>D9QK43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas subvibrioides (strain ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81)|TrEMBL
MAATATSLADARALLLSPLGPVARAGNNGNPVRVSFEFFPPKSDDAEANLWKAVRRLEPL
NPEFVSVTYGAGGSTRERTHRTVQRMLTETTLKPAAHLTCVEASRDEVDQVIQDYKAIGV
DHIVALRGDPPGSAVSGGSGIGGVYQPRADGYANATELAQAIQRVGGFQTSIGVYPEKHP
ESPSIDHDIDVLKAKIDAGATRALSQFFFDIDAFLRFRDRIRAAGVTIPLIPGIMPVSNF
AGLQRMSASCGAAVPAWLAAHFDGLDDDPETRKLLAASVAAETCARLQEEGFADFHFYTL
NRADLVYAICRVLGVREQKVAA
>A0A8F7PNI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain ATCC 19606 / DSM 30007 / JCM 6841 / CCUG 19606 / CIP 70.34 / NBRC 109757 / NCIMB 12457 / NCTC 12156 / 81)|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLDKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A2E2SCV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MLDKISKQEKNIKEFMRGTSVEVTPGGARAIKDFSEILRPGTIVYVTFLPGSDFNATVET
VSRLKREGFYPIPHFAARSIESEKILEEGLERLKEEADTTEALLIGGGVDNPLGPFSASI
EVLRTGLFDKYGFKKIGVAGHPEGSPDITPQECAQAIQEKNDFSCHTDADLYLATQFLFE
AEPLFKWEKAIRSQGNKLPIHVGIPGLATIPTLIRHARQCGVGPSVRFLKKNPIDLFKMS
LSNTPLGKFINAPSSNPSKLIFDIVSGLTVDSDCLINKCHLYPLGGLKKSIDWLYQIQDG
NFSVANGDFIVH
>A0A485NP00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lynx pardinus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEASSRTFSVPPSISRNPAMVNEPRGDGGPTSRSEGSS
SGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DGTGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCCQSREQITG
YLHKAKRLGLKNILALRGGVEPAPCYLRSHFLEGLFCPRSGPLLFSGSRTERAQSPPCQ
>A0A7C9TPE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Galbitalea soli|TrEMBL
MCQRRRVCGAGSDRRARHPPRRDHLPEGAPVARFSFELYPPRSEAAERALHESLGLLVAT
RPEFISVTYGASGSTRDLSLGVLRHLLTTPVPPMAHLTCVGWTYDEASRIIREFLDAGLT
SFLALRGDPPQGFVEGEDFLGDLKSAGELVQLIHRVQAEKAQFHEEAIPGLPGAVRLRSG
RKVTIAVAAFPNGHPRSRSVEQDLDTLLAKEAAGANLAITQLFFEADDYLRFVEQARRAG
VTMRILPGIMPILSPQRLHRMVELTQERMPTALLRRLESVGSPEAQYDVGIQHAIELSRA
VLTGPDDGIHLYTFNKHEAVLDVLDGVGLLPDTVTTPIKENA
>A0A259UEW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa silvacetica DSM 10669|TrEMBL
MSPKCSFSEALADPEQLSITWELVPGRGMREKAQEHLLKMAELAAKDPKINAITITDNPG
GKAAILPYSMAVEAKRLGIDPLVHFTSKDKNRNALESELYALGRADIHNLLVMTGDYPTE
GYAGLAKPVFDFDAVHALRMITKMNEGAYTNLPATHFFAGAVVSPFKATEAETMAQYYKL
HKKIANGARFIITQLGYDARKFDELRKYADSNQFNVPLIGNIYVLSVPVAKLMNKNLIPG
CVVTDKLVKKLEAEQADAANKKEQQLLRAAKLYAVLKGLRYDGVNIGGHGLSYADVQYIM
EKGEEQSSNWQDIAVADFDYPQADGFYFFEKDVTTGLNTCQPFDRRQTGSGHSSLKQSVM
DLVHGVAFDHKAPLYPLNKAVAKFIDNSCLKKPFTIAEYTTKTMTNECRFCGDCAMHELG
FICPMSQCPKQQRNGACGGSRDGWCEVYPEQQKCIYVKMYEGFKGCGKEERMKAKYMPPC
NWELHRTSSWLNYFNDRDYNNNKG
>A0A7C1T891|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccus sp|TrEMBL
MTMTNHHLSFEFFPPKTPEGRKKLQDTHRQLAKFEPEFFSVTYGAGGSTREFTRDIVLEI
QRTGSIASPHLSISGDSHESVLALLQSYKDAGIKRIVTLRGDLPSGMGGAGQLVYANELV
SFIREHFGDTFELLVAAYPEIHPEAESYEKDIYWLGKKFEAGASRAITQYFYNPDSYFYY
LDQCGKAGIDQPIIPGIMPIINYQNLVRFSDSCGADIPRWIRQRLQQYGNDTESIKAFGL
EVVTNLCEKLLAGGAPGLHFYTMNQVEANTALCRNLGFTEELG
>A0A1X7L6K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. J56|TrEMBL
MTTPAVSFEFYPPRNLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYKLNVAAHLTCVDATREETMQIVQDYAVAGVHEIVALRGDAPQGQARFIPHAEGFANSV
ELISAIAERGDMTIRCGAYPEPHPESPDTAADVAWLKRKVEAGASSAMTQFFFEADTFFR
FRDACVSAGIEAPIIPGILPIQSWSGTRRFAERCGTSVPQWAEEAFAASGKEGEAALALD
LCVKLCERLVEGGVDRLHFYTLNKPELVLKVCAALGIKPKDEVPQVA
>A0A238W0I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sediminis|TrEMBL
MSRPKISFEFFPPKTLDASFRLWETARALAPLAPDFVSVTYGAGGTTRKLTHEAVTTIHR
HYGIPVAAHLTCVEATRAETMEIVQSYADAGIREIVALRGDAPKGQDRFTPHPDGFANTV
ELIEAIAARGDMTIRVGAYPEPHPDSSGTDADVAWLKRKIDAGATSAMTQFFFDADTFFR
FRDKCATAGIDAPIIPGILPIQGWAGARRFAATCGTTVPDWAEEAFSKAAAEGPEAERAL
SLRVCIDLCHHLMDGGADRLHFYTLNRPDLTLAVCSALGVRPVRDLGAVA
>A0A1M5GU73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cnuella takakiae|TrEMBL
MKVIDHLRQAKDTLVSFEVLPPLKGKGINALWDHLDPLMGFNPSFINVTYHRSESMFKRR
NDGVFEKVEVRKRPGTVGICAAIMNRYKVDAVPHLICGGFTRQETEDALIDLAFLGIDNV
LVLRGDAPKNETSFEPEPGGNRYATELMQQVIRMNNGHYLEEDLKNAVKTDFCIGVAAYP
EKHFEAPNLRTDIAHLKTKVDGGAEYAVTQMFFDNSKYFQYVQACKDAGVNVPIIPGLKP
ITSKKQLTIIPRTFHVDIPEDLASAIMACSTDAQVEQVGTEWLLQQSRELKQAGVPVLHY
YTLGKPQVVANVVKQVF
>A0A352Q7J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MTERNWQLSFEFFPPKTEQGVANLGHTRKQLAQYAPTFFSVTYGAGGSTRANTQSTVLDI
TAAALDVAPHLSFGGDTEQAVMTLLDSYREAGIRRLVALRGDLPSGMGGAMQLVHANELV
RFIRERFGDLFTLHVAAYPEIHPEARGYDDDVHWLAEKFKAGADQAITQYFYNVDAYWYF
LERCRAEGIEQPVVPGVMPITNYRNLARFSANCGAEIPRWLQRRLEQYGDDAESLRRFGC
EVVSQLCEKLLDGGAPGLHFYTMNQLEPTASILANLGEQPR
>A0A4S4ZUT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp|TrEMBL
MDLQRRIVERRGEFLLFALTPPRRATSPVKSQAIADATVERLQALDLDGLVLYDIDDESD
RNSEERPFPFLPTMDPAEYLSRHLHDWNIPVVVYRAVGKYDEPELRSWLVGQESDRVLSV
FVGTSSRDKPVATSLTRAHALRSEVRPDLLLGGVAIPERHTRKGDEHLRLLSKQAAGCAF
FVTQVVYDLNAAKNLVSDYRYECAARGQDPVPIVFTFSVCGSMRTLEFLTWLGVDVPRWI
QNELRHAVDTLDASFEQALATALELIAYCRRLGVPFGLNIESVSIRRAEIESSVHLAARL
QAELHRAD
>A0A3N6DZW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ADI91-18|TrEMBL
MALGTASTWSDRAHTVRDLLASGSSYSFEFWAPKTEKGERNLWEALRRVEAVAPSFVSVT
YGAGGSTRGGTVRATEQIAADTTLTPVAHLTAVDHSVAELRHVIGQFADAGIRNMLALRG
DPPGDPMAPWVKHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRYFVDK
CRAGADYAITQMFFHPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
DAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A562MJK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium tianshanense|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKTDEMEARLWDTVTRLEPLKPNFVSVTYGAGGSTR
ERTARTVKRILTETTLTPAAHMTCVDAARHEVDEVIQEFAGMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFD
GLQKDPQTHALVAAAVAAEQVLDLVERGVGDFHFYTMNRADLAFAICHMIGIRSHEAEAA
GSAAA
>A0A455W6Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter nauticus|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTRAEIGELLDLYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISDREKIAF
>A0A1G9KH46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea maritima|TrEMBL
MSFEVICEIEPPTKPDLKRVRHQIGTLTTIADAFLIPDNHIGRATVSSVAVAHEVEQMGG
RGIACLNSRDRNLLGFQRDLLTAAAYGVERFLFVYGDKPRSGNRTSDLTVRSMIEEAREF
SPGFRLGAATALRAVPAWKRTADFLFSQVSFSVEAQLRWREEHPVDLPVYAGVMVLASEN
HARGLAAAIPDIDIPDDLVRKVAADRMAGVQAACEQVLALRDSGAFAGVHLVPVARYRDV
ESRLAGVLQAG
>A0A6J4YDX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis Delta 1 endosymbiont|TrEMBL
MIVADKKPVEEIIEYLKEHKSILVLGCNECVTVCEAGGKKEVQVLASALRMNARNQGNEV
KIDEMTLERQCDQEYVEEIRDTIDQYDAVLSLACGVGVQFTAEQYPDTMIYPGVNTCFMG
ATEKRGLWTERCQGCGQCILATTGSICPVARCAKRLFNGPCGGSTTGKCEINAEVDCAWQ
LIVDRMQALDKLDQYETLCPIKDWSSDRAGGPRKVVREDVQQ
>A0A172WD22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola subsp. Schlechtendalia chinensis|TrEMBL
MNSFNMRYHEVLNEYLLNVRDKVQISFELFPPKNEISCENLLQLVDKLKLFNPIFFSVTC
GAFLGKKDNTYNISKKVYQRTGIETVPHLTCINLKREELINVAHKYWENGFRHILALRGD
VEDFNSKPNMYAVDLVKLLKSVANFNISVAAYPEIHPESFDAHSDLINLKKKIDVGANRA
ITQFFFNIDCFLRFRDLCVHNGITIDIIPGIFPIVNFRQLCNFVKTSNVTIPRWIFNMFD
GLDDNIEMREILGASITMDIVKVLYKEGIRNFHFYTMNKFKIVASACHILGMASNVL
>A0A395ST61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sporotrichioides|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WEAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPSAERP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKTIQDIAQLFVSYLNNKIESLPWSESPLTTEADEIREDLIE
LNKRGLLTINSQPAVDGVKSSHPIHGWGPDNGYVYQKSYLELLVHPSVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPV
ANGAVDTEPIANGTAAAAVAN
>A0A542YMH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ornithinicoccus hortensis|TrEMBL
MGTRQPARAGLGARLAAPGRPLLLFSMTPPRQNTPEADRARIAEVMTGRLRDLDLDALIL
YDIEDESDRNPQERPFPYLPTMDPADFRTHLTGWDGPVVVYRTVGKYEPTELKQWLTDQD
PDRVATVLVGASTGSTRVRTRLAEAQSLWRDSGAALPLGAVAIPERHAARGDEHDRMLRK
QAAGTSFFVTQVVYDIDAAKDLVSDYYYACVDRGVRPAPLVFTLSVCGSLKTLDFLQWLG
VNLPRWLLNQLERAEDPLAESLRQCAEIAAGLADFCTRLGMPFGFNIESVSIRRVEIDAS
VQLAAHVREALVGR
>A0A3L7XSY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKSINLQELLRRGTLLADGALGSELYARGVVHGSCLDALNLSDPAAVLGVHASYLQAGAD
LIETNTFGANPFRLASHGHGEQVAAINQAGVALARQAAAASGRAVAVAGSVGPLGVRLAP
FGRVKPEAAYTAFSAQIGALLAAGVDALVLETFSDLMELSEAVRAARDCAAAHSPVLLVA
SMTFTRDDRTQLGDSPAHVARTLAGLGVDVLGANCSIGPAQLLRVLQAMHAAAPQLALSI
MPNAGMPELSGGRVLYPAGPDYFAQLTPDWLATGARIVGGCCGTTPAHIAALRQALDTPR
KAAVHSVSHRPSTPAELLPATDAPTKLATQLQSKRFVITVEMSPPKGYTPHKVLAGAHML
AEAGADVINVADSPLARMRMSPWAVCHLIQQQVGIETVLHFPTRGRNLLRVQGDLLAAHA
LGVRNVFVVMGDPATIGDFPQAFDTFDVAPTALLQLVKQRFNAGVDQAGQEIGQPTSFVA
ACALSLSAPDPAREIKLLRKKLECGADFALTQPVFDAQVARDFFARYAAEHGPLQLPVLV
GVLPLYSERHAGFLHNEVPGIHIPDEIQRRIAGAADAPAEGVRIALELLAELRATTPIRG
AYLQPPFRRYELAAEIIEHTRAQD
>A0A5K1IH47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens|TrEMBL
MRVDEVFKQTASQGTTPVSFEMFPPKGELTLDTARKVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNVSIEHLKQKQDAGASFFV
TQLFFDNEYFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLR
>A0A3D0UP14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNRQEFKERVARGALLLDGAMGTLLHSRGIPIDQCFDAINRLDPAIVADIHRSYIEAGAD
IIETNSFGANRFKLAQHGLEDDVVALNQAAVSVARRVIEGSFRQVLLAGSVGPLGVRLAP
LGRVKTDEAQAAFAEQIEALVALPTDLPQSSGVDLIILETMPDLNELEAAVQAARSIAPD
HSIVGMMTFTRDDRTVLGDTPANVAARMVQMDLDAIGVNCSSGPVQVLRLIAILREVAPD
MPLVAAPNAGWPQQLEGGRVLYPATPKYFADYARAFVDSGASVIGGCCGTTADHIAAMRK
ALDSPADANHPLPHVSSTRQNDITTGATGQPTRLKQALVENRFVVTVEMSPPRGIAPQRL
VAGARMLKEAGANFIDVADSPLARMRMSAWAAAHLVQREVGLEAILHFPTRGRNLLRVQG
DLLAAHALGIRNLFVVMGDPTQIGDFPEAMDNYDIVPSGLIQLIKQRLNTGVDQAGQTID
QPTSFTVGCAVNLEPPDRSRELSLLRKKIRNGADFALTQPIFNPSVAKEFIEAYEKKYHE
PIIPIVAGIQPLYSIGNAEFLHNEVPGIDIPVSLRQRIQQAPDQQQEGVAIAQEILEEIR
PLVRGVYMIPVFGRYDLVADVLDMLGKEH
>A0A7C3FNE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAQILKIVGALAGFAVVVVYALRKILVPTRRYQAPFSPARKDQTSLPLQAFTTFEKGIKG
LFFDCRMCGNCILQETAFVCPMTCPKGLRNGLCGGATPEACEVDPSRPCTWYVIYERSEK
MGREHKLLEINAPIDGALAGHETWLDTIKTWQKREYKPKPLDFFANRAKFNEDWEGLFHE
IRQPKWWQGDSEYHPPAYEDPISLLEANLRTGNFVTTGEIAPPLGASGNIIHKKAGWLKD
YVAAANFTDNASASARMSSVASSRICLEDGLEPVMQLQARDRSRVVIESDVMGAAGLGIR
NILCLSGDHHRFGPGPVSKPDQFDMDAVQIIWMLRRMRDEGVYLDGRKIKRRPELFLGAA
ASPFGAPPKYEALRAHKKINAGAQFIQTQPIFEYNHFLEWLEALDKRNLLDKVYVLAGLI
PLKSARAAHFMADDVPGVYIPPEIVKRMDAAGDKEGQQEEGVAIALEMIEKLKNTPGLNG
MHIMAVHWEAIVPRLIDESGIPKPTFTDLSQISGAAPTT
>A0A3N5RRC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKVSFLDLLSSSSLPILGDGAMGTMLNARGIGFEQCFDELNMTNPGLVAEIHRAYIEAGS
QVIQTNTFGANRYKLAYHGLEGKVKEINQAGVHLLKQIVYALNKDVLIAGDAGPLGVRLA
PFGRVQPEEARSAFCEQIEAQVEAGVDLIILETFSDLHEAREAVAAARQVCDLPVVVSMT
FTRDDRTMLGDAPAQVARLLSESGANVVGVNCGGGPAQIMRILKAMRHAVPNEKLSAMPN
AGWPEQVGGRIMYPANPDYFGEYARSFCEAGAVLIGGCCGTTPSHIAAMRAALDKASDGC
AEPVIEGAGASEVDDRWETAEPPTRFAQKLNAGKFVVAVEMDPPRGLSAHKLIAGASLLT
EAGADVINVADSPMARMRMSPWAVCGIIQREFGIETVLHFPTRGRNMLRVQGDLLAAHAL
GIRNIFVVMGDPTAIGDYPEAMDNYDLVPSGLIKLIKRSFNAGVDHAGADIGQPTSFYAG
CALNLTPQDPEREMKNLRRKLQAGADFALTQPVFNPKDAGAFLKRYEDQYGPLSVPVLAG
LLPLYGPRHAAFLNNEVPGIDISEDYLDRLRRAGDAAPKEGVNIALELVQEMRSWANGVY
LMPAFNRFDIAAEVIEKAKSTRL
>A0A7C3LVB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKSGSKLERILASGHFAVTAELGPPKGPNLEVVERKMQLLTGVCDAINVTDNQTAIVRLS
SVATCAILAQRGLEPVMQMTCRDRNRLAIQADVFGAVALGVRNLLCLTGDHQCFGNHPTA
KNVYDLDSIQLIRMIARMRDEGRTEGGEEVDGAVPLFIGGAANPFGDPFEMRVIRLAKKV
AAGVDFIQTQCIFDMARFKEWMKRVVDQGLHEKVYILAGIMPLKSAGAARYINSNVAGIY
VPEPLVKRMAAAGRGKAAQAEGMKLAAETIQEVREIEGVRGVHIMAVEWEEAIRPIVEMA
GLLPRPVVE
>A0A2U3QIF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfobium mesophilum|TrEMBL
MKSGSNLERVILSGKPAVTAELGPPMSADGHEVTKKANILKGFCDAANITDCQTAVVRIS
SIAAAVLAHREGLEPVMQMTCRDRNRIGIQADLLGAAALGLKNCLCLAGDHQKFSAAGRL
KGHPGAKNVYDVDTCQLVGILKKMRDEGKQEGGDPLEVAPKFFIGASWTPMGDPIDFRPM
NLLKKVNAGADFIQTQGIYDIELFRSQMDKIRNMGLHERTAILGGIIVPKSAMMLKYMDS
SVAGVSVPKALIDRMNKAKEAAGDDKKKARELQEAEGIKLTVELIHQVLETPGIRGVHIQ
AIEWETAIEGIVKDAGLYPRPIFETE
>A0A2G6PDS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNRDEFVARLLERPLLLDGAMGAWIHAKGIPNDISLGTVNVQNPAIVAEIHQEYIEAGAD
ILETNSFAANRLKLAEHGLQKETVAINQAAVDVARRVIAKFPHKSVLLAGSVGPLGATLA
PLGRVSVSQAREAFREQIEALLSAEAGGVDLLILETMSDFKELKTAVTVARDLSADIPII
AQMTFTRDDRTLLGLRPDEVARKLAELDIDVMGVNCSTGPANVLRIVSMMHQAVPERPLS
AAPNAGWPEQLEGGGVRYPATSAYFGEYARSFVDAGARIVGGCCGTRAEHIQAMRAALDN
PSAPKRPLPTIQIVPQEAAAETTAADKPTQMAQDLAAGKFIITVEMSPPHGIATERLLAG
ARMLKEAGATMLNLADSPLARMHMSAWAAAHLVQQEVGVETVLHFPTRGRNLLRIQGDLL
AAHAMGIRNLFVVMGDPTRIGDFPEAMDSYDIVPTGLIQLIKQQLNQGVDKAGRSIDQAT
SFTVGCAVSLTPKDPEREMRLLHKKIKNGADFALTQPVFDPAAAKQFIETYENSYEEPML
PLVTGIKPLYNSRNAEFLHHEVPGMVIPAEQRERMKQAKKQRREGVLIAQETLAQVKDFS
HGTYLIPAFGRFDLIADIIDSLN
>A0A6N6KTR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MMGRGICPSLVSIFGKEVAMPGFTPGRRWQPPFYPFKKLPLGERALAATERLVKGPLFGC
RMCGNCLLQETAFICPMECPKGARNGPCGGSTEEHCYVDETRPCIWYKIYDRATVLGREE
MLLEVLPPLDWDKVGTETWGDVYNRVHQIGAFKVVKGLATRDHVQRTMVWDTIFRPVRQP
DWWEGDAEYHGPQYEEPVSELERRLKAGEFVVTAEVAPPMSTATGKLRENIDLVKPYVTS
INFTDNPSATPRMSSWACSQFAIEKGAEPVMQIAARDRTRTGLQSEVIGAAAMGVRNILC
LSGDSSRMGPPPLGRADVLDIDSIQMLWILRRMHDEGKYLDQRKIKFPPKYFLGAAASPY
ASRPDFQAIREHKKINAGAQFFQTNLVYDLDGFEVWLEALAQRNILDKVHILAGVTPLKS
LRMAQYMHNSVPGVSIPEPLLQRMEYAGEAAGEEGVNIALELIEGIQQFKGVSGIHIMAV
GWESIVPRIVTEAGLLPPDFVTQEEVNVSKEPVNQ
>A0A3M1M646|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
AFAEQVQALAEAGADLLILETFSDLAEMEVAVRAARSVCDLPIVAQMTFAEDRRTPLGYS
PEAVVERLRALEVPVIGANCSVGPARVFAVVQRMASLLYPEGKPLDHPPFLAVQPNAGWP
ERVGGRVVYPATPEYFGHYARRFIATGVRLIGGCCGTTPAHTRAMRLTLNALALTPRPAR
IQVLRPPKVISEEPVTPEAPTEMQEKLAQGRFVVSVEMSPPKGLNHSKVLAGALMLKEVG
ADVINVADSPMARMRMSPWAICHLIQSQVGIETVLHFPTRGRNLLRVQSDLLAIHALGIR
NLFVVMGDPPAVGDYPQASDHYDVVPSGLVRLIKQNFNQGRDHAGTPLGRPCAFHVGVAL
NLGTPKLKREMRVLKKKVDAGADFALTQPVYDVETVHRFLRRYAEAHGPLQLPLLVGILP
LYSARQAEFLHHEVPGLIIPDEVRRQMRLAGDRGREVGVKMAQDLLLALREVVHGVYIMP
PLGRYDMAAEVIGVLGREAEQQEE
>A0A6L7NJW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTTDEPRATGPDYRLRSMLERGEWVLSAEVDPPRGLSAEAGLRAAAALREAGADCVDVGD
SPMATVRMSAIAFAARVQQETGLEAVLHFASRDRNLMALQSDLMGAHMLGLRSAIALSGD
PPSLGQYAGASAVWDVKAEGLIELIATLNKGRDTAGNEIGGRTAFTIAAAANPNNSDQEA
EMARLRQKAEAGCDVFFTQPTFDFPAVERFAERAAGVGRPIVLGVMVLASARNARFMAEN
VPGIAVSDAIVERLEAAGDGAAEAAVDLAQEFVEQVRPLCAGVYLIPTLGRLAGTIEVVR
RLRAQSPGGTP
>A0A7C2JF39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MMSSAAPLAQGRGTAYCPSARQGLTYHPAMDDPLISTGPEAALATGPLTLREKLAVGQFV
VSVEIDPPVGLDARRAIRAAALMKEAGADAVNVGDSPTARVRMSPWALCLLIQREVGIET
VMHYTTRDRNAMAIHSDMVGCHALGVRNVLCLRGDPPELGGYKDVIGVWDVSAVGLVRIL
KLLNDGLDWTGRPIGRQASFFIGAACNPNADPLGPEIRLMRRKVEAGAHFFVSQNVFDPD
RLERFLEQAAPFKRPIIVGVLPLHSYEHAQRLHREVPGMYIPEDVRERLRRAGPDAPQEG
KAMAREVMELCRGRAAGVYLVPTHGNYDLVAELVAEGKG
>A0A7C2XC81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSGNGYLVGSNLERVLRAGHFAVTAELGPPQSADGEVIHKKAALLRGYCDAVNITDNQTA
IVRMSSIAAGAILVQEGLEPVIQMTCRDRNRLAIQSDLLGAYALGLRNLLCLTGDHQTFG
NHPGAKNVFDMDSIQLVQMVTEMRDSGVFQCGENFKGQEPRFFVGAAAAPFAAPVEFRPY
RLAKKVKAGANFIQTQLVYDLPAFENFMENVRELGLHKQTYILAGVGPLKSPAMARYMKT
QVPGILVPDALIERMESAGAPWAGKSKDELTKEDKKARTEAWKETGIQICIELIKGLQQI
KGVAGVHIMAIEWEEAVRPIVEGAGLFPRPAVQESA
>A0A7C1P114|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MMENNGYKAGSNLERVLRAGYFAVTAELGPPKSADAQIIRHKAAILRGYVDAANVTDNQT
AIVRMSSIAASALALQEGLEPVMQMTCRDRNRLAQQSDLLGAYALGIRNCLCLTGDHQSF
GNHPEAKNVFDLDSIGLIAMVKGLRDFHKFQCGEEIAEGAPAFFIGAAENPFAPPYEWRP
FRLSKKVQAGADFIQTQLVYNVPRFREFMARVCDLGLHEHVYILAGVGPIKSPAAARYMR
DQVPGLDVPDEIVARMEAAGRGIEDKKARTQAWRQTGIDICVEIIQQVRDIPGVAGVHIM
AIEWEEAVPIIVERAGLLPRPIVPAVMEGARSDGGPGTVA
>A0A2E6WQL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLKITELHKQRDTNSIFIVDFSPPKSVNTNFLKDAKELNADYISVAYNPSKSIKIFSMIV
AQQIKEKTNKKVVFSLATRDMNKLSTQSILKGAQLLGLNNLIVFKGDNFNEKDLSIQVDD
YTPTTLIKDIKKMNQEKDLKNDKISTDTDFCIGAAVNTSSISNNEIKLTKNKIDAGAHYL
ISQPSDKPDNFLRFHSKYIKKYKKKINIPIFHGILMVNQNSLHYDNISKSLTQDYTQKDS
DGIEKTVSIIETFLKNGINSFYLIPPIYKKGERDYKLANSVIAKIKNN
>A0A196NEV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. TDK1|TrEMBL
MAPPLFADVAGDVAVSFEFFPPKTEKMEETLWASIETLSPLGPRFVSVTYGAGGTTRERT
HATVSKIARETPLAAAAHLTCVEATREEIDQIAEEYWAAGVRHIVALRGDPPRAGEKYRT
HPGGYENAADLVAGLRRLHPFEISVSAYPECHPDSPSPEADLDNLKRKIDAGANRAITQF
FFEAETFLRFRDRAAAAGIDAEIVPGIMPVMNYASVVKMSAMCGTDVPAWMEKLFEGLDE
HPSARQLVTATLTAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGLRPRQQAAVAAA
>A0A536CWX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
RVFVVAGDSQEAAGEFPDSVSLLEAIAAGSPAMNEIGVTGYPERHSFIDDDLTIQAMWDK
RRLATYIVSNLCFDVRVVKRWVARVRKRGVKLPVYIGMAGVADPAKLLRVSTRIGLSDSA
RFLRGHSNWLLRMIQPGGYAPDRFATGLMPELARPDLKVAGIHVFTFNEVEPTEAWRRQM
LSRLRQQG
>A0A1X7S207|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymoseptoria tritici ST99CH_3D7|TrEMBL
MDKITDKIAALPPNANYFSLEFFPPKTQQGFSNLNARLSRMAHSLRPLFVNVTWGAGGST
SAKSLALAEVTQRELGLTTCLHLTCTNMSRKLIDEALEQAKVLGVRNILALRGDPPRSDE
YRDNSLPNADEDDSNKDFTWAEDLVRYIRKQYGNYFCVGVAGYPEGHSDQSCPEHQSMEH
DLPFLVEKMKAGADFIMTQLFYDVEAYERFERRLREHESGAFKTVPLIPGLMPVQSYQIL
RRTTKLSHAALPEEMLKRLHAVKGDDEAVKRVGVDILSEMVEGMKSRKGNGPQGFHFYTL
NLEKVVAQIVERTGLIPPEEKKDENAVADDEVGDFVLVDKDVKQKQRRRKSSMANSQSRN
RVIVARTRASSNSSTRTSAAHEVPDDEAGIPREKINSRSNTLAISEGDGALGREATWDDF
PNGRFGDARSPAYGEIDGYGVSLHVSVPDAKRLWGEPKTIEDISTSFRRHLSGEIEAIPW
SEEPLQNETLTIKDQLQSLINRGWWTVASQPAVNGVRSTDPVHGWGPKNGFVFQKPFVEF
FIPASDWSALQGKLVEHPQITYFAGNANGDFVSSGEDTVNPVTWGTFAGKEIITPTIIEA
VSFKAWCEEAFGIWAEWQRVYKPGSESSRLLERIRKEYWLVSVIHHGFLEEGALWKDLLE
A
>F0Z1Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. D5|TrEMBL
MKISELYQAKQNQGNPSKKTLSFEIFPPKKDSELKNIDKTLAVLCELNPDYISVTFGAGG
GANRNRTIELAKRIKQEYHVEPVVHLTCLHYDKAEIDEFARVLANAGLQNVLALRGDKNP
DMREKESFCHASDLIAYLKGKWDFCFLGACYPECHPESEDKVGEIRHLKAKVNAGAEVLL
SQLCFDNHAFFRFQEACRIADIQAPIIPGIMPVINAAQIKRMITMCGATFPVQFQKIIQK
YESNKEALFDAGMSYALSQIIDLLVSDVEGIHLYTMNNPLVARRICEGIRNIV
>A0A3M1J2S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTDATPMRAGSRLEKVLRSGRFAVTAELNAPDSADPEDVYRNALVLSEVCDGINATDGSG
ANCHMSSLGCCALLTRAGYDPVLQVACRDRNRIAIQGDLLGAAAMGVKNVMCLTGDDVSN
GDQPEAKRVFDFDSVQLLRVARMMRDEGVFLSGRELTTPPKFFLGAASNPFAPPFDWRPL
RLAKKIEAGADFIQTQYCFDIPRLQQFMQRVRDLGLHEKVFILVGVGPLRSDKVANFMRT
KVPGVWIPDEVVDRLAKTPRKKKKAEGIKICIELIQQIREIPGVHGIHLMAYRQEETVAQ
IVRESGVLEHRRLDFDEPHTRRAAKHPPAGSSHQDPTAF
>A0A504C0K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-1-3A|TrEMBL
MTARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A2E0S2F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSGQVEDQSKLERVLRSGQLAVTAELNSPDSHLPESVHRNALVLGSLCDGINATDAAGAS
VHLSSIAVSAILQKAGYEPVMQMSCRDRNRIAMQGELLGAAALNIKNVLCLTGDGVHTGD
HPQAKPVFDMDSINLLKTARTMEEEGRFLSGRKLESNPKFFLGAAANPFVPPYDFRPLRL
KKKINAGAKFIQTQYCFDVPRLKTYMDSVNDMGLSEKVFILIGVGPLKSAKSAQRMRSNV
PGVVIPDAIISRLKQAKDQVAEGKKICLEIVQQVIEMPGVKGIHIMAYGQEALVPEIIAE
SGILDNRNNNI
>A0A2W1AU69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSGQAEGQSRLERVLRSGRIAVTAELNPPDSASPDSVYENALVLATLCDAINTTDAAGAN
VHMSSFATSALLSKAGYEPVMQMSCRDRNRIAIQGDLLGASALGIKNILCLTGDGVQAGD
HPDAKPVFDLDSITLLKTAKRMKEKGTFLSGRKLDTNPQLFLGAAANPFVPPFDFRPLRL
KKKIDAGAQFIQTQYCFNVARLKAYMQEVNDMGLTDKVFVLIGVGPLKSAKSAEWIRSNV
PGVVIPDVVIKRLKGAQSQANEGKKICLEIIEEVLEIKGVSGVHVMAYRQEELVAELITE
SGILNSRTEKY
>A0A1J5CR27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium CG2_30_46_19|TrEMBL
MKAGTNLEKVLESGAFAVTAEAGPAKGAVTSVIERKGEMLKPCCDAVNVTDNQSAVVRMS
SWSSCVLLKRLGLDPVMQIVVRDRNRLAIQSDVLGAVAMGIQNILCLSGDHQAIGNHPDA
KGVYDIDSIQLIQMLKGMRDEKKFQCGEEISGEVPIFIGAAANPFAAPFEYRVLRLAKKV
KAGADFIQTQAIFDVAKFAKWMEMVRDRGLDKQTHILAGLVPIKSVGMARYMKDYVSGVY
VPDEVVTRLEGAKNAKEEGIKICLETIEQLKEIQGVHGIHIMAVAWEEMVPHIVEQAKLL
PRPVV
>A0A3B8XIF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
VAFVRGNGYRLGIGAACSAEKHPESPDLEHEFRYLRLKVEAGADFLITQMFFDNRFYFDL
VARARAAGITVPIVPGLMPVPSRRSLAFVTQMSGATVPDALQAEIDAAADDDAIRRLGVD
HCIKQCVQLLEAGVPGLHFYTFNRARAPIEILGTLRGQQLLAS
>A0A1U6HSQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. P2b|TrEMBL
MSPPSLIDAHPNLTDAAPVALSYELFPPRSAAAAETLWTTIRELETTAPDYVSVTYGASG
SNRDTAVELIHRLLLETTLRPIAHLTCVGNTPQELAGIIGELLDIGARGILALRGDQPKD
GGQPAEGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPSRHPESPSEEHDIEVLL
AKQRSGADFAITQVFFDAEQYVSLLTRARRAGVTIPIIPGVMPLTSLRRVTRLGELAGVE
PSPDLLERLAAADNDIERLRIGVRATVDLANAALDAGAPGIHLYTFNEHQSALEVLDKLA
LPRHQRAASRHSVAARPQLAS
>A0A448F7L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aggregatibacter aphrophilus ATCC 33389|TrEMBL
MSYAKEIDNLNQHLANLNGKINVSFEFFPPKNEKMENLLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLEAAPHLTGIDATPDELREIAKDYWDSGIRRIVALRGDEP
PGYSKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDVGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMASVTNVSIPAWMAKMYEGL
DDDQTTRNLVAASIAIDMVRVLSREGVKDFHFYTLNRSELTYAICPILGIRPTL
>A0A0B7HX34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga canis|TrEMBL
MFVVLPREYNFLLNTKMKVTEHIARSKGKTLFSFEIVPPKKGNSIEELYRNIEPLIEFKP
PFIDVTTSREEFFYKQHPNGLLEKKITRMRPGTVGICSAIQYKYGVDTVPHVLCGGFTKE
ETEYLLVDCFYLGIDNVMALRGDARKEERYFEPTKDGHTYAVDLVRQIKDLGRGKFLHDV
IETDYGTDFCVGVAGYPEKHIESPSMTFDLARLKEKVDAGADYIVTQMFFDNQKYFEFVE
KVRLMGIDIPIIPGIKPITTKKHLNLLPQVFKLDLPEILVSELEKCKTNEDVKQVGIEWA
IEQSKELKLWGVPTLHYYSMGKSDNIVDIVSKVF
>C3R4A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei 5_1_36/D4|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKNGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVVGYP
EKHEESPNIEQDLYWLKKKVEAGADYVVTQMFYDNQKYVAFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAIKCKDDKEARALGIEWCVNQCRELIAYGVPGIHF
YTVGAVENVKEVAAAVY
>A0A1J5J0V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium CG2_30_46_52|TrEMBL
MKLQDILARCKAEQTPSISFEFFPPKTDKGEENLWACIQELAPLNPAFVSVTYGAGGSTQ
SRTRRIVERIKHETALEPMAHLTCVGSTEEDLAALLSQYQASNIENILALRGDAPEGMDS
FEAIKGGFAYATALTAFIHARNDFSIAVATYPEGHPESAGGVADDLKYLKIKQDNGAIAA
ITQYFFDNDHYYRFRDAAEKMGITIPIIPGIMPIANYAQIVRFSAMCGATVPDWLHEKLD
AYADDEHATKQIGIEIATRQSQDLISNDAVGVHIYALNKSEASIAICRNL
>A0A536QZW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARIVDLLAAGRTISFEFFPPKDNEEQRLLTRTIADLQPLRPSFVSVTYRGGRISRERTT
RVVVDLLRTTDLTPMPHLTCVAHPRFELGEIIGGFRAAGLENLLALGGDPLPEEESYKEL
EYASQLVELGRRLGFESIGVAAHPAGHPRSPDLVSDRRYLAAKMTLADFAITQFFFKVEE
YQRLRDEMAALGMNKPIIAGIMPITSLTSVQRMAQLSGYAVPDDIVRLVEAGGDDRDEIR
KRGIAVATQLCRDLLDAGVPGLHFYTLNFSKATREIYTDLGLER
>A0A535IWG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSQSRLAGLLREGRFVVTAELSSSDSADPEATWRQAEVLRGSVDAINCTDNTGAHVHMS
SLAAAHLLVEKGIEPIMQLTVRDRNRLALQADLLGAAALGVRNLVLMSGDDVTAGDHPEA
RRIYDIDSMQLLEVAAAMRDRGTYLSGRKLEQAPTFFIGAVENPFAPPLEFRPLRLQKKV
RAGADFIQTQLVFDVRLFAHFMAMVADLGLVGKVFIIPSIGIPRSARSAHFMREKVPGLH
VPESLVARLERTPQARQAEEGVKIAVELVNAVREIPGVSGVHLIGIKWEEGVVQVAEAAG
LLPRPTLSPLVSAGGRG
>A0A536EDB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRVDSVLTGRRPIFSFEFFPPRSDDGVRQLFETIAQLRELEPTFVSVTYGAGGSVRTRTV
ELVTRIRHELDIEPVAHLTCAGATVAELHGIVDTLRESGIDNILALRGDPPDGAASFPVV
EGGLAHGNELMQLIRDRADVCVGGACYPEKHLESPSFDDELRYTRLKVEAGASYLITQLF
FDNRAYFDFVAKARASGVTVPIIPGIMPVTNVDQIRRFTSKIGATIPDALLEALHTRAED
HDAVLQLGVAWSTLQCAELLAGGAPGVHFYTLNRSPATRAILSALRAARPWERVR
>A0A535YML1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKARLKAAPRSRARSAVRHEHGPRRHAAPHSASIRWRCHHAMTKAAAIGGSPVAIGSRLR
RALDAGRSVITAELAVPATVAHELILERAKGLLRPQIVAMNITDGLRGRPALSPIAAAAI
LTHADLGVEPIVQVVARSRARNALIADLLGASALGVRNLLCMTGDVPESSGDIDDVDVFT
LIELARGFPAGLGTELLGTAEPFCVGAAWSPFAPDPAHEAERLVRKHAAGAVFVQTQPMF
DAHGFAAAIDRLPVSLTELPIIIGLAPIRSCDHAQRLGAIPGIVIPDRLLALLDRASDEA
DACERYWAYLDAELDWLTRNVPHRGFHLMPIGHSKRGIRQSSSFDRLYAAATRALDAAPP
NLAEVAAPVEVSGRVFGTSAV
>A0A536QNS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRGVDRTGRPLIEKERSFSLSALADRLRGSGFIVTAELNPPKSASATVVRRRAEALKGFV
DAVNVTDSNRAMVAMAAVAAAVIIRNAGVEPIVQMTGRDRNRIALQADVLGAAALGIENF
VFMSGDDPKQGSHPDAVNVKDLDGIGLVKMAAGLRDGRFLSGDEIKSGAPKLVIGATASP
FAKPMDADVVKTVDKISAGAEFFQTQPVFDLATFSQWLVEIRRHGSRDVPILAGVLVLRS
AEQADRLAKVPGLAIGREVLDRMNKATDAEAEGVAIAIEQTRSLKALPGVRGVHVYAIEW
PEAVGRVTEGAGLLPREEAKVPV
>A0A497B041|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTEQAPVSRLEKILTKGHFAVTGELGPPKGADRSVIERKAQHLKGNVDAVNITDNQTAVV
RMCSMAVAKMLIEMGLEPTMQMTCRDRNRIAIQSDLLGAYALGIRNLLALTGDHQSFGNH
PEAKGVFDIDSIHLLQIVHGMGEEGVFANGEEIEGGPVRFFLGAAANPFADPFDFRPYRL
AKKVKAGARFIQTQIVFNVPKFAEYMRRVRDLGLHEKVYILAGVAPIKSYGAARYMATKV
PGMDVPEEIVERMRKTPKEKRKEEGIKICVEVIQQLREIPGVAGVHIMAIEWEEAVPQIV
EMAGLLPRPEV
>A0A2W4NTV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPCYSELQRRLQAGQVVVTGEIAPPRGAARATLERLAAGLRDYVDAINLTDNQRGLGRMS
ALGAGIILRQMGIEPVVQMTCQHRNRIALQADVLSGAACGIGNFLAMTGDHPKIGDHPDA
KNVLDLNSFQLIRMLRTMRDEGRFDSGVALTEAPRFFLGGVANPNVERVARLERKIQFGA
EFIQTQIIFDIERFKQWMAEARAGGLHQQAYILAGVMVIKSAASARFLRDRLPGSRVPDW
VIERMERAADPEAEGIAIAAELTNELLAVEGVRGVHLMSVGWTKAIPQVEERAGLLPRPA
APPAAE
>A0A1S1ED41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC076C09|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEASHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQPNFEVN
>A0A2P7YL28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elsinoe australis|TrEMBL
MERISDKIAALPQDGTYFSLEFFPPKTQQGFDNLQSRLSRMSQALRPLFVNVTWGAGGST
STKSLALAELTQRQLGLTTCLHLTCTNMSRRLIDETLEQAKSLGVRNILALRGDPPRSEE
YKAENGDAPEIEDDDSNKEFTWAVDLVRYIKKKYGDLFCIGVAGYPEGHSDQSHPEHQSM
DFDIPYLVEKVQAGAEFIMTQLFYDQKAFDAWEKLLRSHSSGAFKDIHIIPGLMPVQSFQ
ILRRTTKLSHAKLPEPVLKRFEDVKGDDEAVKRVGVDVISEMVETMKISAQNRPKGFHFY
TLNLEKAVAQILQRCDLIPPSTPSIITTLDSAISEEDSDGYLHVKKDDAQERRRRASREA
NNRVIVDRSRRTSTHSSMYEQSEDEISRPSSLGPSRATALAISEGEGSLGREATWDDYPN
GRFGDARSPAYGEIDGYGTSLHVSIPQALRLWGRPASKSDITTIFAKHVRGELEAIPWSE
DSLNAETETIREELATLIQKGWWTIASQPAVNCVRSTDKIFGWGPNNGFVYQKAFVEFFL
PSSDWKRLKETLDQDEQCTYFAANDAGELEASNEDSVNPVTWGAFTGKEIVAPTIIEGMS
FKAWAEEAFAIWREWGLVYKPGSESSRLLKGVREDYWLVNVINHAYVEPKALWETLAKI
>A0A535R289|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSDLLQRGPTFSFEFFPPRTDEEKDRLSQTIQDLEPLHPSFVSVTYRGGRSSRERTTAVV
TDIIRSRAITAMPHLVCVAHSRGELEEIVGGFIEAGVENLLALGGDPVAEEGPGELKHAA
ELVELARALGGSSIGVAAHPAGHPRSPDRESDRRHLAAKLALADFGITQFFFHVEDYLRL
REELADLGLSKPVIPGIMPILSLASVKRMSELAGYQVPADVVDRLGPLEDDPQEFRRVGI
ELAGELCRQLLEAGAPGLHFYTLNFSKATLEIYRSLELRAQWGGPRAGRAEHGRQGGHPP
SERETIA
>A0A535G5R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLSPSRLAGLLRDGHFVVTAELSASNSADPEATWRRAEVLRGSVDAINCTDNTGAHVHIS
PLAAAHLLVEKGLEPIMQLTVRDRNRLALQADLLGAASLGVRNLVLMSGDDVTAGDHPEA
RRIYDIDSMQFLEVAAGMRDRGLYLSGRKLEQAPSFFIGAVENPFAPPLDFRPLRLQKKL
RAGADFIQTQLVFDVPIFARFMAMVADLGLLDKAFIIPSIGIPRSARGARYMKEKVPGLH
VPDALVDRLEKTAPARQADEGVQIAVELVRAVREIRGVAGVHLIGIKWEEGVVQVAEAAG
LLPRPTLSPLATVGGRG
>A0A7Y3LZA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S3(2020)|TrEMBL
MALGTASTRTDRARTVRDMLASGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNILAVR
GDPPGDPMGDWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSVDWDADVAHFVD
KCRAGADYAVTQMFFQPESYLRLRDRVAKASCETPVIPEIMPVTSVRMLERLPQLSNAAI
PSVLKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A7L2VCU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachypteracias leptosomus|TrEMBL
MVNETQHPCSTSSSSRSDAGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITAHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFEDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSENFLK
FMKDCQGIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A432QDG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp|TrEMBL
ARFMEMCRDMGLDKQVYILAGVTPPKSLGMARYMKKFVPGMDVTDEVIDRMKGAKDKQEE
GIDICVDIINQVREIDGVAGVHVMAIEWEEAVAEICERAGLLPRPTFEESAIDETVTAPV
RETIIVREEEAAVGVEENRAGEEILARAKEEAASIIAAARAEADLLKTQAAGGPEIERTG
EKIAGVEDDAGEHEMNEKERLMALESMKLGLEALKKAYGLNDDQFEALMKFASAEAILQK
EPPTGSGAPARGTVAPAPVAGDKPVTAPATPTDAVVQQAKESKAQQEVTSQAEEDAKAKE
AAKARAEAEAKAKAEAEAKAKAEAEAKAKAEAEAKAKAEAKAKQEAEAKARAEEEARAKA
AEQEKKKAKEEEKQAEPIAQSVPGGLEAPKLKAEETPLAERGSKVPPTSYKQEYSGVIRE
VVLGNGDSAVTVGGAEVLPFHLFEGNQPHKPLIAMEVQDIVPDNWPTTLTRYFDDVMDNP
VAWAKKCVNEYKADALNIYLIGTDPNGENRPSADAAKDAAAIIDAVDVPIIVWGCGNNEK
DTETLRDVTSLIGNKKVCLAPLEDANYRAIGATAMAFGHPMVAASPIDVNLAKQLNILLE
NLGVPLDTVLMDPSIGALGYGIEYTYSVMERIRIAALTQKDEKLQVPIICNLGREVWKTK
EVGLASDDLLGDQERRGIMMEAMTASCMMLAGGEVLIMRHPKAISMTKSLIDGLIG
>A0A524LZ16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
QTHELVRRVNAETWIHAVPHLTCVCHSQREIDQILDDYAQINIGAIMALGGDPPGNGAAD
CRPEFPHAIDLVRAISAFNASGRHPSPDGFGIGVAGFPEGHPATPNRKQEMDYLKEKVDA
GADYICTQLFFDNRDFLDFRDRCVLAGITIPIVAGVMPIANRGNYERIPSLALGARYPAA
LIRRFDGMEGDDEVENAGIEWAIDQCAGLVREGVNGIHLYTLNKFRVVKTIWDAIDPR
>A0A2J6WNX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfovibrio aggregans|TrEMBL
MSNLKKKLMNGDFVITVEITPPKGPEISQMVNKLQELKLLVDAVNFTDNPSGKMRMCSLA
ACKISLDLGFEPVLQMTCRDRNRIGIQSDLLGAHALGIRNLLVMTGDHPILGDHKEAKPV
YDIDSSILLKMVNNLNRGIALNGNELNGKTDFFYGAVVNPNADPLMPQLKRFEQKLKMGA
EFFQTQMIFELALLEKFMEHAGKFNTKVIAGIVIIRSKKMLHYLASKVPGVNVPKWLIDR
VEKLKEDDVEKFGLDFSAKLVLDIIDKKLCHGIHIMAFSKVEEVKNLLNFIKLK
>A0A0H3GGD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae subsp. pneumoniae (strain HS11286)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>B1MP24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)|TrEMBL
MTTNPLDRDGPVAELQDPGSIADRLTAVQPGEIAFSVEFMPPRDEAAEARLWRAARVFER
YRPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWVPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPTALEERLLRAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTARG
>A0A2R4TKU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WCHA45|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRIVHQELQRLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVDIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A5C5BDR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Miniimonas arenae|TrEMBL
MTTSELYRAPRPTISFELYPPRTPRGEEQVHETAARLAAGEADYFSVTYGASGTTSERSQ
ALVEHLLAETRVPVIAHLTCVGRSRSQLRDVVSGLLDAGVRDFLALRGDPPEGGEWSPGG
DGLARACDLVALIREVEAERFGLPPASPVERLVARRTRRDGVSIAVAAYPGYTVPGLSGE
FQVRDDELTALRAKQDAGADFAITQVFFDVEAYVALQRAARAAGIVLPLVPGVLPLTDPD
RIRRLCALNRIPEPAELLAELEAAGGPEEAYALGVRRTADLVRGVLAAGAPGLHLYTFNQ
HAAVTRLLDEVLAPA
>A0A0U9HRP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfovibrio aggregans|TrEMBL
MSNLKKKLVNGEFVVTAELTPPKGPEINQMIDKLKELKPLVDAVNFTDNPSGKMRMCSLA
ACKISLDLGFEPVLQMTCRDRNRIGIQSDLLGAHALGIRNLLLMTGDHPILGDQKEAKPV
YDIDSSILIRLINNLNNGLDINGNRLNGKTEFFYGGVVNPNAEPLIPQLKRFEQKLKMGA
EFFQTQMIFEIEKLEKFMDYAQRFNTKVIAGVVIIRSKKMLHYLNSKVPGVSVPKWLIDK
IEGFNDEDVEKFGIDFTAKLILNIMEKKICHGIHLMAFSKVEEVKNLLNYIKI
>A0A068MRM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechocystis sp. (strain PCC 6714)|TrEMBL
MELEPNLSPLDAMTISQFRRAAEAKKFLITAEVTPPKGGNPERMLAVAAKLRGRVHGVNV
TDGSRAVLRMSSIAACVLLQQQGIEAICQMTCRDRNLIGLQGDLMGAYALGLRNVLALTG
DPLKAGDHPKARPVYDLESVRLLSLIRSLNQGLDFNQAPLLDGRLDLFPGAAVDPQLKSW
SGLQSRFERKLTAGAQFFQSQLITDFERLDKFMSQVAAGCGKPILAGIFLFKSAKNAAFI
RRVVPGVNIPDALIDRLAQAEDPLMEGVAIAAEQVKLAKELCQGVHLMAIKKEELIPEIL
DRAGIKPFGESGNG
>A0A5E8TC71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. 3R-3a1|TrEMBL
MTQHNFSIEFFPPKTPEGTEKLRVTRAKLAELQPKYFSVTFGAGGSTQQGTLDTVLEIIR
EGHVAAPHLSCIGSSRDALRAILTEYKSHGIKKLVALRGDLPSGFGAADFSSGEFRYANE
LVEFIRAETGDWFHIEVGAYPEMHPQAKSPQDDVQNFARKIKAGADAAITQYFYNPDAYF
NFVDEAQKLGVNAPIVPGIMPITNYTQLMRFSDMCGTEIPRWIRLKLASYGDDADSIRAF
GLDVVTQLCEQLLEGGAPGLHFYTLNQPAATMAIWQRLVD
>A0A388LMJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chara braunii|TrEMBL
MKVSEKIHQSMKEGKVSFSFEFFPPKTQDGVENLFDRMDRLVSLHPIFCDITWGAGGSTA
ELTLDIATRMQTVVCVETMMHLTCTNMPVEKIDDALEKVKDVGITNILALRGDPPHGQDT
FVAVEGGFRCALDLVRHIRAKHGDYFGITVAGYPEAHPEKIADPSAGATAEAYHEDLLYL
KSKVDAGAEVIVTQLFYDVERFLKFYSDCREIGIDVPIVPGIMPISNYNGFKRMTTFCKT
AVPAEISAALEDIKDNDEAIRSYGINLATEMCKRILAAGVNHVHLYTLNLERSAMAILER
LGVIQDVNLARPLPWRPPVSGKRSSERVRPIHWANRPKSYLIRTREWEEFPKGRWGDCRS
AAYGSFNDHQFTRPKSRDNKLKKEWGSRSYGSVDDVKEMFVKYCKGELKSFPWSEAEGLL
PETKKINDNLVRINGQGFMTVNSQPAVNGEKSDAPLVGWGGRGGYVYQKAYVEFFCSPQK
LTSLVERIESSFPSISYMAVTADGDVKSNVSSEAVNAVTWGVFPAREVIQPTVVDPASFM
VWKDEAFAVWGNELGTVAVGGDVAAKEVMECIRSTFWLVCVVDNDYVNGDLFAIFQGL
>A0A432Q7J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp|TrEMBL
MKSGSNLERVLKSGEFAVTGELGPPKNSDPEVVRKKARILKGNVDAVNITDCQTAIVRMS
SIGAGLIAQSEGVEPVIQMTCRDRNRISMQSDLLAASAMGLKNLLCLTGDHQKFGNHPGS
KGVFDMDS
>A0A1C5E3E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DconLS|TrEMBL
MNPAVSAPAAVGTDLLDDFSLEMTGKDVPALEEARGSIPQGTRINVTFLAGEDHATRLAA
ARAVRGLGFVPVPHISARRLPSSAALEGFLAGLAEDGTADNVFVVGGDPARPEGPYEDAL
AVLRTGLLERYGVRHIGISGYPEGHPAISGPALWSALTDKARAIGAGPFTGDVITQFGFD
ADPVLDWLAAVRARGVDLPVRIGVPGPAGIRRLVGYATRFGVTTSASVARKYGFSLTNLL
GTAGPDRFLHALGERYDPARHGVVKVHFYTFGGLRTTAEWVGGFRERTR
>A0A1S2PV04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MUSC 14|TrEMBL
MPAVGAALLEDFSLEMTGKDVSRLEEACDSIPPGTRINITFLAGEDLGMRRAAARAVKRL
GFVPVPHISARRLPSRDALDAFLSALAEDGTAENVFVVGGDPARPEGPYEDSLAVLRTGL
LQHHGVRHVGISGYPEGHPAIADGTLWSALTDKAAAIGAQRFGGDVITQFGFDADPVLTW
LEATRARGIHLPVRIGVPGPAGVRRLLGYATRFGVATSASVARKYGFSLTNLMGTTGPDR
FLHTLARRYDPERHGTVKVHFYTFGGLRRTAEWIADFRHGEDTNHTS
>A0A6J4TBK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Sphingomonas sp|TrEMBL
MDQSFLGTLQRWLMAPRVGALPAPAAMPAPQLSFEFFPPKTEALEAQLWACVRRLAPLRP
RFVSVTYGAGGSTQARTHATVSRILRETTLTPAAHLTCVDASRAEVDRVAREYWDAGVRH
IVALRGDQPPGVERYEPHPDGYAYAADLVEGLRRIAPFEISVAAYPEAHPTALSADHDLD
NLKRKIDAGATRAITQYFFDTDVYLRFLDRCAAAGITVPIVPGIFPVNSIIQVKKFSAMC
GASVPDWMDHLFDGLENDAETRRMVSAVVAAEQVRLLQANGVDEFHFYTLNRPDLVYAIA
HILGARPASAEASAPASANGVAEERAAAAASTPP
>A0A1C5QGZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKINELLKKRPTLSFEIFPPKNNENDITSIYATIDELAKMNPDFISVTYGANGSTSKNTC
KIASTIKNKYGIESVAHLTCMNNTKEEIKDILTELKENSIENVLSLRGDYPKDGDGINHG
DFKYASELNSYIEENFPNDFCLSGGCYPETHYEARNFDEDLLNLKKKVDAGAKYLVTQIF
YDNQYYYRLVREARKIGINVPILAGIMPAHNPKQLRNIAKMSNCSVPFDLAAMIDRFAGN
PKAGKEVGLHYATYQIIDLMTHGVDGIHIYTMNKPEIAKEILKRTEYIRDEFFKD
>A0A1Z9E891|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrionales bacterium TMED122|TrEMBL
MNSGNSIRRIFEEKRPLFSVEFFPPKNEEGGKRMIRTAAALQPYKPDFVSITYGAGGGTR
ETTMRYATILKEEHGFEVMPHLTCVGHSTYELMEILEGFAEAGFRNVMALRGDPPQGENE
FRVTEGGFRYASDLVALIRENFPDFGIGVGGYPEKHPEAPDFETDMTNLKTKIDAGADFI
TTQLFFDNQAYFRFVENCKNAGIQIPILPGLLPALSLGQVQRFCKMCEAYLPAKLEESLQ
DSPTENHPDIGAKWALNQVSELLRENCPGFHLYALNKPESTLAILEGLSRNP
>B0N047|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes putredinis DSM 17216|TrEMBL
MNITDLIQGAVASRTTRFAFELLPPLKGDGTRSVFGAIDPLMDFNPAYINVTFHREALKE
DIRPDGSREWHIMRRRPGTVGISAAIRRKYDVEVVPHLICGGWSKYDIEDSLIDMDFLGL
HNVLALRGDKRQNEPRFVPYAQGHAHAADLVRQIQAMNRGEFIDGEVEECHHSKFSVGVA
GYPEKHFEAANAQSDLQYLKEKVDAGADYIVTQMFFDNSKYFDFVERCRKAGITVPIIPG
IKPISTPKHLEILPRTFSVSLPEELVKAVRACGEDTQAAREVGIEWAIHQAKELKAAEVP
IIHFYTMGRTDNIRKIARNVF
>N9QJX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 101966|TrEMBL
MSKQIPISFEFFPTKTDLGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAADLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVDKVNTGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A5N5DK63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lasiodiplodia theobromae|TrEMBL
MEKITDKLAALPPDGRYFSLEFFPPKTQMGFANLQNRLERMASALRPLFVTVTWGAGGST
ASKSLELAELTQRQLGLTTCLHLTCTNMSRSLVDEALEQAKALGVRNILALRGDPPRSEE
YREGEADKENDSNKDFTWAVDLVRYIRAKYDDYFCIGVAAYPEGHSDQSHPDKQDPKFDL
PYLIEKTKAGADFIMTQLFFDIKAYEEFEDMLRNDPSGVFKTIPIIPGLMPIQSYQILRR
TTKLSHAKLPPAMLARLDAVKGDDEAVKSVGVDILSEIVEELKTRSNPGPRGFHFYTLNL
EKAVAHIVERCHLITATSPNEDEEAVTIEDIPVNGGGPSDSLKVKNRRRLSSANSTPHNR
VVVDRPSTSSNKSYEALADEAGVPKDKIMTRANTLAISEGEGTLGREATWDDFPNGRWGD
ARSPAFGEIDGYGVSLHVSIPQAIRLWKYPTTVEDISDIFRRHIVGELEAIPWSEEGLNP
ETETIREQLLKLIAKGWWSVASQPAVNGIKSTDAIFGWGPKNGYVFQKPFVEFFLSSADW
EKLQAKLDELPDVTYFAGNHAGEFSSNDEDSVNPVTWGSFAGKEIVTPTIIESVSFRAWL
EEAFSIWSEWRHIYPPRSATANLLGQIRDDYWLVNIIHHDFVEKDALWRLLLDE
>A0A2D2D4G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylosinus trichosporium OB3b|TrEMBL
MADARTSWPPGHFDISYEFFPPKTPEMEIQLWDSIARLAPLKPKFVSVTYGAGGSTRERT
HNIVARLVAETDILPAAHLTCVSASRAEIDEIVRGYWNAGVRHIVALRGDPPTGVGTKFE
PHPIGYQSSTELVRGIREIGDFEISVSTYPEGHPESRSIDDDIDALASKIDAGATRAITQ
FFFENDVYFRFLDKARKRGIKIPIVPGIMPVQNFKQTANFARKAGASVPGWLADRFEGLD
DDPVTRRLIAAAVAAEQVLGLAENGVREFHFYTNNRADLVFAICHLLGVRPVTEKAAA
>A0A1C3VQF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium lusitanum|TrEMBL
MAHIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEEVYERAAIF
SGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPHDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLNEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDAVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEMVHESGVLKGRQPWKHEANQTDALIAERLEHIRGGKEENQQEMAEAAA
HHPPHKTH
>A2VU73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cenocepacia PC184|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGPHFYTLNAATATRTICERLAM
>A0A6J7VUD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSLLREKLEKTNDVVFTAEFPSVDGGGMASVEKNAARLAPWFDAVNATDNPAAHAHTSNT
TTAIAMKMHGLEPIMQIVCRDKNRLAIQSDMMGASLHGITNISLLTGDDVTAGDEPEARR
VFDVDSAQAINIARILATGKYLSGRKINPAPDFYLGAVENAAAPPFDYRIQRALKKYRAG
ASFLQLQICYHPERLEAFCKGVAEVAPDLKLIPTVVLIKGAKGLGFMNDKVPGIDVPDSM
LARVQNASDQSNEAYALTLELARHALSLPGVRGLHVTDFRHDDSLGNLMTDLGQTPRSSI
TNR
>A0A848P5W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia insidiosa|TrEMBL
MNDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILNTYRENGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGDAFHIEVAAYPEYHPQARSPKHDLDNFARKVKAGANSAITQYFFNADAYFQFVA
DAHKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWVAKRLESFGDDRESIRAFGLDV
VTALCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A6J7NWF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MDRGAGSVTSAPTRLAGLARSRNQLATLASSRNRPIVTAECPSADGGTIDDLAARLATIA
PFVDAVNVTDNPAAHAHASNVSMAIALAGLGIEPIMQIVCRDKNRLAIQADIAGAAMFGI
VNFSALTGDDVTAGDEPEARRVFDLDGPQLVSVLAGMKAGTYLSGRKFTPTGDFFIGAVE
NPGAPPLDYRADRALLKVNAGAQMLQLQISYRPDQLEAFMSACVANGVAQRAIVLPSVCL
TKGARALSFMNDKVPGISVPAETIDRVANADDQAEEAYLLVRDLTVYALQLPGVAGIHIT
DFRHDGSVQRLTEELRIGPRFDSAIAETGTNPEHEERHAHSS
>A0A6J6DLY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVLGTSYSFEFFPPKDAEGEERLWHAIEGLKSIAPDFVSVTYGAGGSTRDRSIRIAREIT
DRTGIPTVAHITCVGSTRDELLEILHSYQDAKITSILALRGDPVGGPLAPWIPTENGFAH
ADQLVELARDCGGFTIGVAAFPDGHPSSGGDFNKDIDVLVRKEQLGATFATTQFFFDVQA
YVNLVERLAKRGSSLTIIPGILPVTNVKLLHRMAELGGTPVPPDIAKAFADVESDTQAVR
NLGVEIATKLCQELLEAGAPGLHFYTMNSSTATVEIYRRITNAQ
>A0A7W5J7J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas sp. OG2|TrEMBL
MTALSFEFYPPKTDEQRAQLDRTAEKLKGYGPEYVSCTFGAGGSTLSYTSETVRHLNQQH
GFSAAPHLSCVGGSREEIRELLKLYRAIGCKRIVALRGDLPSGMGHPGDLRYASELIAFI
RSEHGDTFHIEVGAYPETHPQSDDALSDLKYFKAKVDAGADGAITQYFYNPDAYFHFVDA
ARKLGVDIPIVPGIMPISNYSQLKRFSEACGAEIPRWIAKRMQAYGDDVDSIREFGADVV
ANLCERLIAGGAPSLHFYTLNLAKPTQAVLSRLGR
>A0A1F5ESC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Campbellbacteria bacterium RIFCSPLOWO2_02_FULL_35_11|TrEMBL
MDFQNALNDKQFPIVLELSPVREPQNEENKRKIKEIIDVSGITAISITESPMGVSAMPPE
ELGSFIKNSSNLEVILHLSCKGRNRTQIKSRLESYYRKGLTNLLVVTGDYPKDSKPVFDL
DSVQVLDLIACLEQKNCGLNNKTISLFAGAVCSPLHPLQELQRQKLDLKIQAGARFIVTQ
VGYDFARLKLFKERFDKKKYDVPVLGNIFIPNLKLIDRIFRGEIPGCTISKGLYNFLSSS
SSENILKVYAWMMNEMRKMGFVGIHLGGPLVQNHQNLKKLLEYFQQLQKYPEEDFYRSIF
YSDDENSNYKIFPTTSFLEKTHYQLSSIAHKVLFNGGNKRTRILKKLSFMEHTVKAALYG
CKDCGECTLPDSAFLCPQSGCAKQLLNGPCGGTREGGWCEVYPTRLCFWVRVALRNPEFK
IKFTPPKQWGNIKGSWDTL
>A0A839NSM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. R2-1|TrEMBL
MPSDSRHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVNATREEIDAVVQSYWDAGVRHIVALRGDPAEGVG
YSYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFDNEIYLRYRDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLDNDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
VAAAKAAA
>A0A6N7D554|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylophilus sp|TrEMBL
MSASASAVESKALPVSVEFFPPKTPEGVVKLRGVRRQLYGAIAPQYCSVTYGAGGSTQRG
TFDAVAEILAEGVPAASHFSCIGATRESVREQLAQLQAMGARRLVALRGDLPSGYGAGGE
FQYASDLVAFIRAETGRAFHIEVAAYPEVHPQARSPESDLQAYAAKVRAGANGAITQYFY
NADAYFRFVDDARAAGADVPVVPGIMPITSSSQLMRFSDASGAEIPRWIRLRLQAYGDDV
ESIRAFGLDVVAALCERLRAGGAPGLHFYTMNQSTATLELCRRLNLGARLASA
>A0A1I1R4V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium phragmitis|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAIDLVKQIKDLNCGQYLHEVIDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAVQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A502G0R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas glacialis|TrEMBL
MTVSVAQMQEARLALATPLFADLAGDARVSFEFFPPKTEKMEETLWESVQTLAPLGPRFV
SVTYGAGGSTRERTHATVARIARETTIPAAAHLTCVDATREEIDAVAHEYWAAGVRHIVA
LRGDSPVAGQPFVSPVGGYENAAALVAGLRKLHPFEISVSAYPECHPDSPSEAADLDNLK
RKLDAGATRAITQFFHEAETFFRFRDAAAKAGIDAEIVPGIMPVMNFGAVQRMSAMCGTV
VPPWMGTLFDGLDDRPAARQLVSATIAAELCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GIRAQPALVAAQAA
>A0A3G2TA39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. 6424|TrEMBL
MKITEHLEKAQGKTLFSLEVVPPPKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERKITRMRPGTLGICSAIQHKYNVDTVPHVLCGGFSMEETEYLLVDCMYLGIEN
VMALRGDAMKGQQHFEPTPGGHKNAVDLVHQINNLGRGKYLHDDTICAENTKFCIGVAGY
PEKHIEAPSINYDLKWLKQKVEAGADYVVTQMFFDNRKFIEFVTKARAAGITVPIIPGLK
PIATKSHLQILPKIFKIDLPEDLISEVEKASDNTAVKQIGIEWTIQQCRELMDFGVPVLH
FYSMGKSDNIRRIASELF
>A0A0G0ARV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma harzianum|TrEMBL
MHIKSLVAETEKSKAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPRFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLDKVNDALQKAYKAGCTNILALRGDPPRDQES
WTAADGNFQYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEELLLDHLKEKVDMGAGF
IVTQMFYDADNFIRWVGKVRERGITIPILPGIMPIATYASFLRRAKHMQCRVPPDWMAKL
EPVKNDDVAVREIGKTLVAELCKKLLANGIHHLHFYTMNLAQATRMVLDELNWTPSAENP
LKQALPWKQSKGFGRRDEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPASIQDIANTFVQYLEKKLETLPWSESGLAAEADPIKDDLVA
LNKRGLLTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLMPPYLLEEMISRLDDFP
NLTYYAVTKNGQLKSNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGVDW
AHCFDANTPSRALIEGIMNEWYLVNIVNNDFRENSTIFAFLEGLEVKDLAVPVTGSA
>A0A517DUI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa termitida|TrEMBL
MLISKLGKSFVFTTELGGINGTDIGESIARVRQYQGLDAINIHDCPNARLRMNSIMAAAV
IKRETGIETIPHYTCRDRSLLGTQADLLGAHALGIRYLLPTTGDGPQHGPYQSKAVYDYN
TAGLIALINSLNQGQDANGAAFTGPTQFTVAATATPAAANMAAELANMEKKTNAGADFFQ
TQPVYDAGQAEKFINQAKTLRKPVLLGIMPLKSLKMGDFINKHVAGVTVPANILAELEQG
KSGFAIACEFIRQVYRQVDGFHIFGMGDVAVTNQLIDFTKKLRGES
>A0A0R1TE43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schleiferilactobacillus paracollinoides DSM 15502 = JCM 11969|TrEMBL
MISFEIFPPRANASEKATNRFYASLDTLASLEPAYISVTYGAGGNGNHASTLALCRYIKE
HYGIDAVAHIPAVAFDQQSLKTYLADLEDAHVENVLALRGDLPADGRPNNDFPFASDLVT
AIKRESDLNILGACYPDVHPEADNCVVDVQHLKEKVDAGVSQLITQLFFENGHYYNFLER
CELAGIKVPIQAGIMSVINERQIAKMATMGGVGLPPKFLKMMHHYQDNKIAMRDAGIAYA
VDQIVDLLSEGVDGIHLYTMDNPVVTQRICSAIKTLI
>A0A6M9Q2V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. MWH-UH21B|TrEMBL
MELSVEFFPPKTPEGENKLHLVRERFSEKLKPSFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
AETGDWFHIDVAAYPETHPQAKSPASDIDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YDLGVTQPIIAGIMPITNSSQLLRFSDACGAEIPRWIRLRLQSYGDDIASIRAFGEEVVT
DLCDQLLTAGVPGLHFYSLNQADAVLAIAENLELTN
>A0A243N3I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis subsp. medellin|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIEYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVEYVR
EKQEVKEGIN
>A0A2E9RC56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MKQNRVTHINRELQNSIHDTKRRLGQRPSPDFVSLRQHVSVSFEFFPPASIEMERKLWSC
VAQLAPLSPRFVSITYGAGGSTRQRTHATVERILAETSLTPAAHLTCVGTTRDDADEVVQ
RYWDSGVRHLVALRGDSADPGRPFAPHPQGYQTAVQLVAGIRKIADFEISVGAYPEIHPD
AKSQEADLDNLKRKLDAGANRAITQYFFDVDDFFRFLDRAQNVGISAPIVPGILPVTNFA
TVVEFSKKCGTTIPVWMQDLFAGLDDAPEIRQLIAATVAIEQCRLLLEQGVSEFHFYTLN
RAELTRAICHALGLRDYREDSLCELNVPGR
>A0A2E8MJ03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MVVMIAKLIARTEAFFKGMMFDCHACGQCVLSETGLVCPMSCPKGLRNGPCGGTLEGGCE
IYPDKECVWMRIHRRTSKGAFSLPELIPSPDSSLHFTSSYLNLITGKDKASRTPLPYLDL
PKNRVSLPQQTVSKLEAKLRSGRFVRTCEIRAPRGPDFARFREQAVIVRGQFDAVNATAY
LNGKPSLPSPVAAAELVRLGIEPISQATCRDHTKTSFISEIMENEMNGVHNMLCLTGDSY
AGNPKIKQVFDMDSTLMLYEARCFRETGVIHFLKEKADRPSKMFLGAAINPYSTPTNVPI
RRLKQKAAAGADFIQTQAILDTAGFRRFMELVVAEGLDKELFILAGIPVIVSRSALEMVS
HIPGVKLPPEVWRRLAGAEDLRHEGVTLAREILQDVRDFPGVAGVHLMLFGSDHSVLLDV
IEDLADRRIKNESECLSKN
>A0A5P3MP69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria animalis|TrEMBL
MSYAKEINALNHNLAELGSDINVSFEFFPPKNEQMAAMFWNSVDRLKVLNPKFVSVTYGA
NSGERARTHDIVKNIKRQTGIEAAPHLTGIDAAPEELRRIAQDYWNSGIRRIVALRGDEP
AGYQAKEPFYASDLVALLRDVADFEISVAAYPEVHPEAKSAQADLINLKRKVDAGASHVI
TQFFFDVESYLRFRDRCVAVGIDAEIVPGILPVTNFRQLGKMAKVTNVKIPSWLARMYDG
LDHDQGTRNLVAASVASDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRPQADAA
>A0A267TSW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldibacillus hisashii|TrEMBL
MGLIQDLEKQILIADGAMGTLLYSYGIDRCFEELNVSNPQEIERIHREYIEAGAKIIQTN
TYGANRIKLARYGLENEVQEINAKAVEIAKKTVKTSGKPVYVLGTIGGIRTFQKAIFSTN
DILQSFEEQLDILLKEQVDGILLETYYDLDELKAVLEVARKKTDLPIMANVSLHEKGVLQ
SGTPLAEGFNQLIDLGANIVGLNCRLGPYHMIQSFEEIPIPNGAFLSAYPNGSLPRMEDG
RLVYESDEQYFYEAAIQFVKEGVRLLGGCCGTRPEHIRAMAEAVKNLSPVTEKKVIKEKP
IIQLTQIQQVHEPSLVDIVKSRRSVIVEFDPPKTLPMSQFLSGVSALKNAKIDAITLADN
SLASPRISNVACAQIVKNRYHLRPIVHLTCRDRNLIGIQSHLMGLHALGIHDILALTGDP
TKIGDFPGASSVFDLTSFDLIRLIKQFNEGLSYSGTSLGEKTNFTVAAAFNPHVKIIEKS
VARLEKKIHSGADYFITQPVYSEELIINIYDATKHLDVPIYIGIMPLTSTRNAEFIHNEV
PGIKLPDSVREQMKKVGNDKEQGKREGIAIAKHLIDVAFDLFHGIYLITPFLNYQMSVEL
INYIHEKEQMKVEREITSV
>U2KTB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp. oral taxon 892 str. F0426|TrEMBL
MDMEQERVNIREHIKKEPLIFDGGMGTYYAQKTHTRGKGVELANIETPIVVEEIHTEYLR
AGAQAIKTNTFAANRIVYQGDTALVERILHTGFEIAARAAEPFGAYIFADIGPVTGLPPA
DIIEEYYFLADSFLAAGARHFLFETNSSAEGLVETAAHIKQVCPDAFVLTSFSAFPGGYT
RDGFFVEELVRVAVESGYIDAVGFNCVSGVQSMKELVHLLGTCSLPLSLMPNAGHPIVVD
GRTFYESAPDYFGKGLAAIVGDGVSIVGGCCGTTPDHIRALCGALRDEGSVTAEAEERAV
RTALAPSRSPFFDALRAGEIPIAVELDPPETGNADKFMAGALELQAAGIHAITIADNPIA
RARMDAAMLAGRVYRSLGLEPIPHMTCRDRNLNAIKSILLGLSAEGIHNMIAITGDPIPT
AERDEVKSVYQFNSRKLSAFITNLGERGDVVPFHIFGALNVNSQHFPSQLGLAKKKMEAG
MTGFFTQPVLSARAKENLRTARDTLPGALIIGGIMPVVSERNARFMESEISGIHVEERII
NAYHGLDREAAEELAVQLSLEIAKDIAPYIDGYYIITPFSRTSLVARIVKELTARRLAQ
>A0A4Z0EFZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum sp. Q1|TrEMBL
MPNASQHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVAATKEEIDGVVQSYWDAGVRHIVALRGDPAEGVG
HSYRPHPGGYAQTCDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFDNEIYLRYRDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLENDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
PAVKPEAKAA
>R7MYV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera elsdenii CAG:570|TrEMBL
MHTNELFAKKTVFSFEVFPPKRDIPVETVYPTLAELSKLHPDFISVTCGAGGTGGNRTVE
VAAHIKALGCETAAHMPCIYLTEESALQNLKELKEAGIENILALRGDEVPGRERAHAFEH
ASDLVAFIKEKEPDFNVIGACYPEGHTEAKTLAADIRNLKTKVDAGASELISQLFFDNAL
FYRFLERCEIAGINVPIEAGIMPVTNKAQIERMVTLCGATLPIKFQRAIAKYGDTPESMR
DIGIAYAVDQIADLLANGVDGIHVYTMNNPYIAKKIAEAVKTLL
>A0A443BW86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHESEAA
GSAAA
>A0A238Z7G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacillus rhizosphaerae|TrEMBL
MNAVPVISFEFFPPKTADGMEKLRNARTQLAAFAPQFFSVTFGAGGSTRDRTFETVVDIQ
QAGFEGAPHLSCISADKAEIRDLLAQYQAQGIKRLVALRGDIPSGEVSSGDFRYANELVE
FIRAETGDWFKIEVAAYPEFHPESSSPGADIQHFKHKVEAGADAAITQYFYNADAYFRFM
DQSRKLGIDIPIVPGIMPIYNFTQLARFSSVCGAEIPRWLRLRLQDYGDDLASLRAFGAE
VVRTLCEQLLAGGAPGLHFYTLNQAGTITSILEQLDLQQR
>S7YW19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis 29/42|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDMVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKHIHQATHALFNHQSLG
>A0A5N0L4Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas cyclobalanopsidis|TrEMBL
MTAISFEFYPPKTDEQRGQLDRAAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAPDALTDLKHFKAKVDAGADAAITQYFYNADAYFHFVDE
VQRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMLAYGDDSESVRAFGAEVV
AKLCERLVEGGAPGLHFYTLNLAKPTVSVLKLLNG
>F2RNV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton tonsurans (strain CBS 112818)|TrEMBL
MRTTSPWSSSPPKTQMVRLASSPAIAIRLTEYRLQGSSNLQARLERMSQALRPLFVTVTW
GAGGSTAARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEETKALGIRNILALRGD
PPRSEEYNIDGEDDSNKDFNYAVDLVKYIRKKYGDYFCIGVTGYPEGHADESHPEVQDPL
KDLPYLIEKTQAGADFIMTQLTYDIEAYKKYEALLRNHESGTFKNIPIIPGLMPIQSYHT
LTRVTKLSHAKIPPQILAKVEACKADDEAVKRVGVDIVSDLVESIKKIATPGHRGFHFYT
LNLEKSVSFILERCNLIPPSSEAPSDSELEFESAVYAASGASNGVATPDGRSTNVNRLRA
SSMNSQPHNRVIVDRLTRASDRSERSSTVHETSAQTAGYPALNPPNRNTALQISEGLGSL
GREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTAQVARKLWGTPTCRDDISNIFKRLL
SGELHAVPWSEGGAGEEGGLNPETAMIKAELLKLVEGRGWWTLASQPAVNGVRNDHPVFG
WGPRGEGFVFQKAFVEFFCSGDDFHSKLKPLLQSYGHDEFAWFATNAKGDFQSSTSPETP
TQPPTDPTEVPFDADPLTEMDNGSVNAVTWGVFRGKEIVTPTIIEAVSFRAWGEEAFGIW
EEWRRVFPRGSPSEKLIREIKDDVWLVCVVGQRFGAGGDVGKESNEEDGKLLWKVLAGEQ
TK
>A0A528A110|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDPIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A4Y3KCX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas uda|TrEMBL
MSERPAGVSAATVNPPAAQPRLDDARADGASSATRPGVPTGAHVAADPRPLGTLDRPTLS
FEFFPPRNPQAAPRLWETVRQLEAVHPDFVSVTYGASGKTRETSRAFVSRLLRETSLSPI
AHLTCVGTSRDEITTIVEEFLDEGVRSFLALRGDPPAGQADWQAHPDGLETASALVGLLR
DIESRRCGASPAQAVRARVRPLSVAVAAFPRGNAATGGTRAQDVASLLAKQEAGADFAIT
QVFYDAESYLGLVAEARAAGVVIPIIPGIIPLTDPARLLRTQELTGVPVPRDLLDALGSA
DDASAAHRIGTRAGVDLVKGVLDGGAPGVHLYTYNKHEAALDLLEGAQLDGSTR
>A0A4R2T782|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. PP-F2F-A104-K0414|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGLSFEFFPPKSEKMETQLWEAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPSEKVAAA
>A0A3A5RG10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidaminococcus sp. AM33-14BH|TrEMBL
MKIKELLDSPKVTISCELFPPKKGTELQNAMDIVHAIAIDGVDYMSVTYGAGGTAVGKSL
AIASEVERSGVPALAHLTCIGAKKDGIARVLRDMKAGGIDNVLALRGDRPQGMDELPESD
FPHASDLVRFIKETGDFCVGCATYPEGHPESRTLDEDLENMKRKVDAGCDFLVTQMFFDN
EMFYNFMYRLLAKGVRVPVVAGVMPITNAKQVERIFTLSGTPIPSKLRAVVERFGDHPEA
LRQAGMAYTTGQIMDLIANGFNHIHVYTMNKPEVIGGIRRTLSEVIKL
>A0A432FMK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEKIANYKAQGKTFYSFEFFPPKTDYGLDNLYSRIDRMASFQPAYIDITWGAGGSTA
DKTLGMCKTIQKYFGLEVMMHLTCTNMPVSSIKKVLTEAKENGLSNILALRGDPPDGSSS
WKQHENGFRCGADLVRYIRKGFGNYFFLGVGGYPDGHHEQSNLDIDISFLKEKVDAGSDI
VVTQLFYDVDKFLFFRDKCIKSNIKVPIIPGIMPIHNYARFLKFTQFCQVSIPDSVSTQL
ESIKNDDSSVINYGIDQAAEMCQKLIENGVPGLHFYTLNLEHSVSAILKSLGFVSSRSTL
RELPWRQSASDDRKTSEDVRPIYWSNRPVSYLTRTENWDDFPNGRWGDIASPSFGELNQY
HAIRAGSKSDKVKSRRKKMWGEPKSIRDITDIFVSFCKGKINSLPWCEMPLALESQQISS
DLITLNEMGFFTINS
>A0A3R6XJF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces astaci|TrEMBL
RNMGKIIDRLTELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSA
FKDEKLWLKIGSHIQNEFKIDVLMHLTCHLPREQLREILKNVRAAGIRNILALRGDPPIG
SERWKAIPGGFQNAVELIRFIREEHGDWFCIAAAGYAEVHTEAWNNPNLPPSDQARRVDM
LRLKEKQDAGADFIITQFFFDVDKLLQWIRDCRQVGITIPILPGYYYYVPPQVEDALVTI
KNDDSAVKKYGIQLAVDTCRKLLANNLSLHFYTMNLATTVRTVLEGLHLIERERGLPWGA
PITRTKDGTLEKSIEQVRPIFWSNRASSYIARTSEWDDFPNGRWGDRTSPAYGELSEYYL
AYKRPKVARDALPWCEQGLSGESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWG
GKDGFVFQKAYVEFFVPPHLMQRLVVRSYLCEYVTTFWFLLGGWHLGGARRLPQLYVWLL
LLINGEIGTEYTNSPGPSVTAVTWGVFPGKEIIQPTVVDTASFAAWKDEAFELWLSQLVL
MGSNNVEDSDIFKIFARVITESMTKDDLRQRVLELEGKNEKLHETVAKLKIIQADANREL
KDLHGDLSTSREENSRLKAQVRELRSRLAMAEL
>A0A5E6VHU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSEERRYSFEFFPTKTEAGHEKLMAVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLE
HEVKVAAAPHLSCVGDSKADLRGLLSEYQAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQAQNFEADLSNFVRKVKAGADSAITQYFFNADSYFY
FVERVQKMGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSASIQAFG
EEVISNMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2D9XW81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MNISTKLDEYNNQGKTFYSFEFFPPKTDFGLDNLYSRIDRMASLGPAYIDITWGAGGSTA
DKTFEMSKTIQKYFGLDVMMHLTCTNMPSDSIKKILSDAQKNNISNILALRGDPPDGSSA
WKKNDSGFNYGADLVKFIRKEHGNNFFLGVGAYPETHQEQKNADLDISYLKEKVDAGADI
IVTQLFYDVKNFLLFRDKCSQAGINIPIIPGIMPIHNYARFIKFTQFCKVSIPNSVSDAL
ELIKNDDSSVIDYGIEQASNMCEKLIEEGVPGLHFYTLNLEHSVTEILSTLDLVSTHKSN
RVLPWRQSTLDQRKLSEDVRPIFWSNRPVSYLTRTETWDDFPNGRWGDISSPTFGELNQY
HAIRAGSQSDKVKARRRKLWGEPISIKEISDVFVSFCKGKINSLPWCETPLAIESKQILD
DLVALNQEGYFTINSQPKVGGLPSEDPNFGWGAKGGKVFQKAYLEFFTSKDNLDRLVLRL
DELNDISYQALSFDGDLISNLSENNVNAVTWGVFPGQGILQPTIVDARSFLIWKDEAFGL
WINDWASIYKTNSDSYNLLHQIHDTHYLVNIVDNDFIDGNMIKHILEK
>A0A2D5UPQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEKIANYKTQGKTFYSFEFFPPKTDFGMDNLYSRIDRMASLQPAYIDITWGAGGSTS
NKTLEMCKTIQKYFGLEVMMHLTCTNMRVSSIKKVLIEAEKNDLSNILALRGDPPEGSSS
WEQHEDGFHHGIDLVRYIRKEFGDHFFLGVGGYPDGHQEQSDLDADISFLKEKVESGADI
VVTQLFYDVDKFLFFRDKCIKAGIKVPIIPGIMPIHNYARFLKFTQFCQVSVPDSVTVQL
EPIKYDDSSVINYGIDQASGMCQKLIENGVPGIHFYTLNLENSVSAILKSLGLVSSQGII
KELPWRQSTSGSRKTSEDVRPIYWSNRPVSYLTRTEIWDDFPNGRWGDIKSPTFGELNQY
HAIRAGSKSDKIRAKRKKIWGEPKTIKDITDVFVSFCKGKINSLPWCEMPLAQESKQISD
DLLKLNEMGYFTINSQPKINGLPSEDAEVGWGGSGGRIYQKAYLEFFTSKGKLDRLLKSI
GSKENISYEAINISGDLITNLPENNAMAVTWGVFPNKEIIQPTIVDTRSFLIWKDEAFSL
WMNDWASIYEPKSGSYKLIKEIYDTYYLVNIVDNDYVDGELIQQMLIF
>A0A6G3ULB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID9124|TrEMBL
MALGTPSTRTDHARTVREMLATGATSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVKATQDIAAESTLTPVAHLTAVDHSVAELRNMVGQFADAGIRNILALR
GDPPGDPMGPWVEHPQGVTYAADLVRLIKEAGDFCVGVAAFPERHPRSEDWDTDIRHFVD
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCDTPIIPEVMPVTNVRQLERFSQLSDAKL
PDDLKERILAAKDDPAAVRSIGIDFATRFSAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A1L9NG57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus tubingensis (strain CBS 134.48)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDVQDPARDLPYL
IEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPQVLSKLEEVKHDDDAVKRIGVDIITDLVYGIRDLVSPGLRGFHFYTLNLEKT
VSFILERCELIPPYTEIDDSDALVDGGNLSAMDSSSYIAPNGVPIRTLASRRSSVSSIPH
NRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEEDSNGLNAETAVIQPELLTLIDKKGWWTLASQPALNGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNPDDPDPIDIN
PANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDETK
NDVWLVCVVGQEFGAGTEAGSEEEEDEKKWMWRELANSQ
>A0A7Z9Q9R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISDKLEDFKTQGKTYYSFEFFPPKTDFGLDNLYSRIDRMASLQPAYIDITWGAGGSTA
DRTLEMSKTIQKYFGLEVMMHLTCTNMPVSSINKVLVDAQENGLSNILALRGDPPEGNVE
WEKHEQGFKYGIDLVRFIRKEFGDDFFLGVGGYPDSHQEQSDIDKDISYLKEKVDAGSDI
VVTQLFYDVDKFLVFRDKCSTIGIHVPIIPGIMPIHNYARFIKFTQFCKISIPNSVTKTI
ESLKNDDSSVINYGIDQATSMCEKLIAEGVPGLHFYTLNLEHSVSGILELLGLTSTQRSV
RELPWRQSTAENRKTTEDVRPIYWSNRPVSYLTRTETWDDFPNGRWGDITSPTFGELNQY
HAIRAGSKSDKVK
>A0A5E7JS04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A0N9W896|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLAQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGEHFHVEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A7X0FB65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter aganoensis|TrEMBL
MPHQNAALAPSNLRPPSLAFGDVSVELSPQQALKFTPDVKVLPLGTRIFLTHLSSAALPV
QVEAAARLQAMGYSPVPHLAARNFVSVAEFVEHLAAHGRNGISQALFLGGNPLISTGPLT
EAAMLLSHPAMAQSSIRTAFIGGYPEGHSAIAPDVLGDALKRKLARCAELGIKPHIVSQF
AFDGEVMAAWARRLQSEHPGLAVRIGLAGVTSLPQLIKFAAMCGVGPSLAALKRSGTGLF
NVLSDRDPADLIETIEAAYPKPAGPLDIHFFPFGGWQKTSDWLAGYRSR
>A0A4V6Y703|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. PJ-16|TrEMBL
METQKQFKRRFSFEFFPPKTDKGWEKLQGVRNTLAEVDPDFFSVTFGAGGSTRDRTVQTV
LDLHKRGVSTAPHLSCVGATRDSIAELLDVYRENGINRIVALRGDMPSGMGAAGELRYAN
ELVTFIREHSGDTFNIEVAAYPEFHPQARTAEDDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTRMCEKLLAAGAPGLHFYTLNQAEPSVSIWKNLGLGEREKIAF
>A0A2D9XS34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIEHINNSTDTQFSYEIIPPLRGKGIKIIIDMIEDLKKFNPPFIDVTSHSSSAQKFQN
GQTVLKRKRPGTISICGIIQNRFNIDTVAHLVCNGFTKEETEDALIELSFLGITNILAIS
GDGNPKKIIQAGKSINKNSLELIHQIKNLSKGDYLHEIANSSTIDMCMGVGCYPEQHAFS
SDFDQEIDLLKRKIAAGASYAVTQMFFDNSKYFAFVDRCRKENITIPIIPGIKILDKPRQ
IDILPKLFNIELPDELHSEALENIEHIQEIGTRWAIKQSEELINAGVPVIHYYLMNNTSC
MLNILNHLHK
>C6H337|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces capsulatus (strain H143)|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRVAGYPEGCDDQDDPDLLMQH
LKEKVDAGGTFIITQMFYDVDNFLAWVNKCRENGITVPIIPGIMPIHTYAAFIRRSNWTK
IRIPPDWLEALEPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQATKMVLG
ELELIPSHKTPLQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTD
SRSPAFGELDTYGIGLKGTNEQNIKLWGEPKSLKELSEIFVRFLNGNLDRLPWSEGAVTE
ETDVLKLDLLDLNRRGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVI
DDVISRIEQNPDLTYYCVNKIGELRTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWK
DEAYRLGDDWAKCHVASSPSRRIIQQVMDSWYLVNIVNNDFHKTHDIFNIFKDLKVENLN
VQVEPIAPAAELVDNTRENSQDPQKQVNGSSTELTESKQEIPSN
>A0A2E4L1E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIEFLEKANKTLFSFEIIPPTRGGSIDRVFNLVEALIPFDPPFIDLTSRSAEVYYEDA
GEGKMIRFIRRKRPGTIGISAAIKNKFNVETVPHILCRGFTREETEDALIELNYLGINNV
LAVRGDELRKDAPDSPGKTRHRYASNLVSQIKDMNDGKYVEELIDAAPTNFCIGVGAYPE
KHFEAPNMATDIKYLKAKVDAGADYIVTQMFYDNSAFFKFVDDCRSAGIDVPIIPGIKIL
STEKHLSVIPKIFYVDIPEVLSEKVIGQSKEDIVNIGVEWALEQVQELVEAKVPCVHFYI
MSSAKSAAKVVSQFK
>A0A2E0PKD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISDKIKEYKKHNKVFYSFEYFPPKTDFGMDNLYSRIDRMSALGPAYIDITWGAGGSTA
ERTLGMSKTIQKYFGLDVMMHLTCTNMNAKSINDVLLEAKESNLTNILALRGDPPDGSEE
WQKKNQPFNYGVDLVNYIRKNYNDTFFIAVGGYPETHQEQSDADLDIDYLKEKVDAGVDM
IVTQLFYDIDKFFIFRDKCLSKGIDIPIIPGIMPIHNYARFRKFTEFCNVSIPKNILKKL
EPIKNNDANVIQYGIEQGSIMCEKLIKEDVPGLHFYTLNLEHSVKEILHSIGLVTDQMQN
RDLPWRQSSDEDRKSSEDVRPIFWSNRPVSYLARTENW
>A0A5E7UVR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLSQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHVEVAAYPEMHPQARNFEDDIANFVRKANAGADSAITQYFFNADSYFY
FVDRVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>M3YY87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mustela putorius furo|TrEMBL
MVNEPRGDGGPPPRSEGSSSGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQNQGQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVKH
IRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDDAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFAHYLSGEPNQHGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPVVGWGPNGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPEPEQDTQAL
>A0A1I2C2T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax wautersii|TrEMBL
MSETTTPAAGAAAAAGRFPVSFEFFPPKTPEGAEKLRAVRQQLYARQPEFCSVTYGAGGS
TQEGTFGTVREILAEGFSAASHFSCIGATRESVRGQLAQLKAMGVQRLVALRGDLPSGYG
AGGEFHYASDLVAFIRAETGRDFHIEVAAYPETHPQARSPEADLQAYAAKVRAGADSAIT
QYFFNADAYFRFVDDTRRLGLDVPVVPGIMPIMGSTQLMRFSDACGAEIPRWIRLRLQAF
GDDVASIRAFGLDVVSELCAQLRARGAPALHFYTMNQSGPTLELCRRLGL
>A0A4Q5SJ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriaceae bacterium|TrEMBL
MKIIDHIKNANGKTLFSFELIPPLKGQSIQGIYNAIDPLMEFKPPFIDVTSLREDYLYKQ
HDNGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHMLCGGFTKDETENALIDLQFLGIDN
VLVLRGDARRGDATFIPTKGGHCYATDLLQQVVDMNNGKYLHENYDGIEKTNFCVGVAGY
PEKHFEAPNLKSDFQYLKQKVDMGAEFIVTQMFFDNQKYFDFVNKCRENGINVPIIPGLK
PITASKQLVSLSKTFFIDMPEDLCDAVEACKTEKDVKEAGIEWMINQCKELVNFGVPVLH
FYTMSNAGPTRRIAEAIF
>A0A5E7MYV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A5N6BYL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbispora catharanthi|TrEMBL
MALGLPSRLPDRVPTVRELLAAGERSFSFEFLPPKTDEGERQLWRAIRELEGLRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPRGGNPLDEWVKHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSATIESDTKYFV
QKCRAGADYAITQMFFRAEDYLRLRDRVAAQGCDTPIIPGIMPVTQMSTIARSEQLSGAP
FPPEVAERFEAVADDPAAVRRLGIEHAVELCQKLLDEGAPGIHFITFNRSSATREVFQAL
HSVPAAVAG
>A0A3P9DG59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maylandia zebra|TrEMBL
MVNQVQRGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMDPET
AGSRWSSSLHAHVPLCFFYRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY
CGLESILHLTCCNQSKEKITGYLAKAKHLGLKNIMALRGDPIGEDWEEEEDGFNYAIDLV
KHIRSEFDDYFDICVATPGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFLKFLD
DCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNYGIQQ
AVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSPSQTEGRRC
STIFWASRPKKSCFRPQGKFLVSSFWELNDYYLFYLRLQNEESVFEVFTCYITAQPNRCG
HKVMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPPGYFQ
YLQMGYSESAIVNMDGRNLTNAPEMQPNAVTWGIFAGREIVQPTVVDPVSFMYWKDEAFA
LWIEQWGKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPER
ETETQVLVL
>A0A8J3VER1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizocola hellebori|TrEMBL
MFELVCEIEPPTKPELRKVRHQIGVLSQVASSFLIPDNHIGRATVSSIAVAHEVAAMGGR
SIACLNSRDRNLLGFQRDMLTAAAYGVNEFLFVYGDKPMAGDRTSELTVRAMIEEARGLD
FASGFRLGVTSGLRKVPAFKKAADFAFAQICFSVPDLLRWREANPLSIPVYAGVMVLASS
TMALRLAGTIPDISIPQSLIDRVAQDPRAGVDFACSQIEEIRASGAFDGVHLVPVSRYRE
MALRLEN
>A0A7Y1A6F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas veronii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYHPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRALLTQYKGAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2A7E1F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS094611|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTEKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLEYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAALNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLKQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>C6J2A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. oral taxon 786 str. D14|TrEMBL
MKPDLRTTLEREIIVGDGAMGTYLYQLGFPVGISYEEFNLLRPDVIGDIHRRYLDAGARL
LETNTFSANYYKLSKFGLEAKVEDINRAAVRIAKQAAGERAYVAGAVGSIRGGKRANVTV
QELGKYFEQQIAALLSEGVDALLFETFYDLGEMRIALGQARKLTDVPVICQFAVDQIGRT
LDGFTIPQAFGALVEEGADVVGFNCHSGPKGIMGVMDDVEGPLNVPMSVFPNAGLADYID
GEYVYGATPDYFGECARAFADLGARLIGGCCGTTPEHIAAMAKALEGYAAQPLAKERKLP
EPHLSASVSLNEQPNAVPAGSSETGAVSGGGENRKLPSLTELVKERHTVIVELDPPRDLD
IGKFMEGAAALKEAGIDALTLADNSLAVTRMSNMALGHLVQSQLGLRPLVHIACRDRNLI
GTQSHMMGFDALGIDHVLAVTGDPARFGDLPGASSVYDLTSFEIIRMIKQLNEGISFSGK
PLKQKAKFVVGAAFNPNVKHLHKAVERLEKKIASGADYIMTQPVYDPELIVAIKQATAHL
DVPIFIGIMPLASGKNAEYLHNEVPGIQLSDEVRKRMEGLQGEEGRAMGVEIAKELLDTA
MEHFNGIYLMTPFMFYEMNVALTNYIREKSKRDSAHLSRLS
>A0A0S1X8T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermococcus barophilus|TrEMBL
MVELRIFGCPKSLLNGPCGGAFNGKCEVNENHCPWLGVLERVHYLDGAVLFNEHPILMEI
GKIPSRDVKPKNSNFWSQVEKGRALSVEFPIAAVKNEEDVAKIVSQITPELYTIPDNPLG
YPHFSPTAFATHLKHFGIEVMPHLTAKDRNLTALTAELKTAVLFNFEVVLLATGDWPSLA
LPSRPVFDLDSTNMIRLARFVFNGVLPTKETFEVKERPRVAGAMNPHYKPRVEAQRIARK
LMAGAELFFTQVVATKESVTRIKETFIELKKYINAEVPVMVSLLYPISDDIKPLLRRMGI
QTGDDTFEEVLEEVKALDVAGGVNLIILSRNLDVWLSLWREAYEKIKEVLR
>A0A7C7J0I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirales bacterium|TrEMBL
MTHNIPRLREALATKPFVTTIEFNPPKGTDASKVMTLAGKMVGMVDGVNVTDNTAAVLRA
GSISLCRLLYEIGHDPVMQITCRDRNRLAIQSDLLSAHLLGIRNLLCLTGDYPTVGDYKD
AKPVYDIDSIQMMQIIDGMNKGHDMNGKTLRGVTELYIGAAMSPDMEPSGLAKTKFETKV
NAGASFFQTQAIFDADRFKEFMTFARQFNVKVIAGIILLRSAKMALFLNDNIPGLTVPQD
MIDELEAAPDDKACDIGIDIAVRIINAIRDSCDGVHLMTVTAIDRLPDLIKRAELR
>A0A7C7W657|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MTRISIELVPRSSESLAGDLKILSEGFKSVQMVNIPDILRYELRSWEACRQAKSTVPCAI
PHLRAMDFDSDALDPLKELLSSGDLEEVLVVQGDPPQDLGHRVFPTKSVDLIRAIKSLSP
QVKVYAAIDPYRSSFRQEMAYIEAKVDAGADGFFTQPFFDQGLMEVWADLLGGAEVFWGI
SPVTSERAQRYWETKNNAIFPESFKSTLEWNRQFAKEALAWAKSRNTNIYFMPIRLDLIR
YLGGIL
>A0A7R8AR19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus puulaauensis|TrEMBL
MEKITDKIAALPPNANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRQKYGDYFCVGVAGYPEGHPADSFQDVQDPKVDLPWL
VEKTQAGADFIMTQLTYDIDAYTNFENLLRNHESGAFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPRILEKLEEVKHDDDAVKRLGVDLLAELVEGMRKLPTPGSRGFHFYTLNLEKT
VSFILERCNLIPDYTDDDALAISEEVSLLTADAAKAASSTRRRRASSLSSLPHNRVIVDK
ISEPSSKESVTHEATAASAGMPAQPPDRNTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVSPSVAHRIWGYPVSAEDISKLFRRHVSGDLHMVPWSEGGAEENTS
GLNAETETIRAELLALIDNKGWWTLASQPAVNGVRSDNPVFGWGPPGEGFVFQKPFVEFF
CPTSDFTNTLKPLLQKHGHEKLTWFATNANGDFESSLPAQTSDTEPIEMNPNNVNAVTWG
VFRGKEIITPTIIEEVSFRAWGDEAFGIWDEWRRIYPRSSPTERFLEKTKNDAWLVCVVG
QDFGAGTEIGSKEEDDERKWMWKALANC
>A0A5H6P4V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Adjame|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1Q7EDK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium 13_1_40CM_68_15|TrEMBL
MSAFASLLRSGEFVITAELNPPKSAAANVVRRRGEALKGVVDAVNVTDSNRAMVAMAAIP
AATIVRSSGVEPIVQITGRDRNRIALQADVLGAVAMGIENFVFMSGDDPKQGNHPDAVNV
KDLDGVGLVKMAVGMRDQARFLSGDEIKQPPKMLVGATASPFTKPMEADLTKTFEKIAAG
AEFLQTQPVFDLAIFSQWLVEVRRGGAREVPIIAGVLVLRSAEQAERMAKVPGLALGPDV
LERMKKAADAEAEGIAIAVEMVKALKALPGVRGVHLYAIEWPEAVARVVEAAGLLPRPQA
KVAVGT
>A0A354BG85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPQRLIDVLNRGTFAVTVEYNPPKGTNISAVLENAKQLVGRVHGVNITDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGKDMMGNKLDGSTAFTIGAAVTPEADLIGPVLAKFEVKV
KAGA
>A0A1C5LUS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MKIRELLRQEQTSLSFEVFPPKKDTDFANVETATLGIAKLQPSYMSVTYGAGGSTKGNTI
QLASEIQQKYNVPAISHLTCVCASKENIKAALNEMKSAGIENILALRGDLPNNFEGEVFT
DFAHASELVAFIKENGDFCVGGACYPEVHPDSPTKADDLEGLKRKVEAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIIPGIMPITRRAQVKNAVKLSGCNVPERFKNIVDRFGDNEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEIAAGIQANLSEILKV
>A0A1I1CDW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis marina|TrEMBL
MRKVADRLTREHRPTFSVEFFPPRDAADEQILWRSIRELEPLDPAYMSITYGAGGSSREG
TIRNIARVASDTTLVPMAHLTAVGHSVSELRTVIGHFASVGVRNILALRGDPPGDPLGPW
SPHPEGLNYAEELVRLVRELGDFCVGVAAFPYGHPRSAELDTDTAHLVRKLRAGADFAIA
QLFFEADDFLRLRDRISAAGCDSLLIPGIMPLTTMRTLRKTIELSGANPPQWLLDRLEPL
SDDPKAFRAEGLDIVTELCERLLAEGVPELHFYTFNRAKATRELVSRLGLRPPALLPAVE
PLARA
>A0A1V9HF01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas phaseoli pv. dieffenbachiae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A533B6Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPKRLKEVLDQGAFAVTIEYNPPKGTNISAVLDNAKQLVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYEIGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGRDMAGNKLDGSTAFSIGAAVTPEADPLGPMLAKFEVKV
KAGAQFFQTQAIYHPEQFTSFMKAVRPFKVKVLAGILVLRNYKMAEFLNANIPGVSVPKE
MIDELKAAGDKAEDVGVEIAVRTIKAVRPYCDGVHIMAIKATHRLADIITKAELG
>A0A2N0XPJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. vnigr-6D03|TrEMBL
MSYTHASHIDALNQNVAELSDDINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASRDELVNIANDYWSNGIESIVALRGD
IPPGGGAPDMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFADINNVKVPGWMAKQFE
GLDDDPMTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A134CNU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonellaceae bacterium DNF00751|TrEMBL
MRTTDLFTQKTVFSLEVFPPKRDMPLESIYPTLQELSRLHPDFISVTCGANGQGGNRTAE
VAATIKHTYHCETVAHLPCLYLTEDDVRHTLQELKVHGIENILALRGDETPGKTPIRVFE
HATDVIRFIKEEDPSFTILGACYPEGHTEAKTLGADIRYLKQKVDAGADELISQLFFDNE
LFYRFLERCEIAAINVPIEAGIMPVTNKNQIERMVSLCGATLPVKYQRLLAKYGHSPVAM
RDAGIACAVEQIIDLLANGVDGIHVYTMNNPYIAGKIAAAIKNLI
>R9HSB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides uniformis dnLKV2|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A1C6HPA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MRTNELFAKKTVFSFEVFPPKPDTPIETIYAALDELSQLYPDFISVTCGASGSGSGGNRT
VEVASAIKHTYGCETAAHMPCIYLTEDDALRTLDELKKAGIENILALRGDETPGRERAHV
FEHASDLVAFIKQNAPEFNVIGACYPEGHTEAQTMAADIRNLKTKVDAGASELISQLFFD
NATFYRFLERCEIAGISVPIEAGIMPVTNKKQIERMVSLCGATLPVKFQRAIAKYGDNAE
AMRDIGIAYAIDQIADLLANGVDGIHVYTMNNPYIAKKITEAVKNLL
>A0A5H6AJV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Offa|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>F6IZ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus pentosus MP-10|TrEMBL
MNLKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHQSYIQAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAVTAREHADHPVYILGTIGGLAGDTDAAVQR
ATQAEIAANVTEQLTALLATEQLDGILLETYYDLSELLAALKIVKAHTDLPVITNVSMLA
AGVLRNGTSFTDAIVQLHAAGADVIGTNCRLGPYYLAQSFENLAIPADVKLAVYPNSGLP
GTDQDGAIVYDGEPSYFEEYAERFRQLGLSIIGGCCGTTPLHTAATVRGLSSRSLVPHNA
PTHVAQAPTLVTTKSQHRFLHKVATEKTVLVELDPPRDFDTRKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTAIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGSHSLGIEDILAV
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TDVSTKSISRKLSYGCDYIITQPVYDLANVDALADALAANQIDVPVFVGVMPLVSRRNAE
FLHHEVHGIRLPKSVLERMQQAELDGNERAVGITIAKELIDGICARFNGVHIVTPFNRFK
TVLELVNYVQQKNLTKVQ
>A9W343|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum extorquens (strain PA1)|TrEMBL
MPNASQHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVDATKEEIDGVVQSYWDAGVRHIVALRGDPAEGVG
HSYRPHPGGYAQTCDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIEALKAKVDAGADQ
AITQFFFDNEIYLRYRDKVRAAGIEIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLENDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
PAVKPEAKAA
>A0A161PHN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus trypoxylicola|TrEMBL
MNLLEKLENSILVGDGAMGTLLYEQGIDTCFEAINLSNPSRITEAHKAYIDAGANVIQTN
TYAANRLKLEKYGMAHLVKEINRKGVEIANEVANDEIYVLGTVGGIRRYQMEEWSLAEIK
SAFFEQMTELLKEGVDGLLLETFYDIEEAIMATKLARKLTDQPIVVNVSLGEVGVLQGGV
LLEKAHQQLVEVGADVVGLNCRMGPFHMLKSIEGIPIPKDRYLAVYPNASLPDFRDGRYY
YQSNTDYFADMGKRFIEQGVRLIGGCCGTTPEQIRAFAKVAKSSKPVLEKVVKPRLEISH
QMPVEKIQETLPEIVKKRSSVIVELDPPKRLAVDRFLKGAKALKEAGVDAVTLADNSLAS
PRVDNMALGAMMKNNHSVRPLVHVTCRDRNLIGLQSHLMGLHALGIHDLLAITGDPTKIG
DFPGATSVYDMTSFQLISMIKQLNEGISFSGKDLGQKASFSVGAALNPNVRHLDKAVMRM
EKKITSGADYFMTQPIYNEKQIIQLYNETKHIEQPIYIGIMPLTNTRNAEFLHNEVPGIK
LTDQIREVMAKHGDHKEAAAKEGISIAQSLIDVALEHFNGIYLITPFLRYEMTVQLTNYI
RSKTIEKEKSFL
>A0A143XSL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium CHKCI001|TrEMBL
MKIKDILAQDKVTLSFEVFPPKTNLNYESVEKATTEIAQLKPDFMSVTYGAGGGTSEFTV
DIASNLYHNYGVNSLAHLTCVSSTKEQVHRVVERLKEEGLENILALRGDLPKDRTLLENA
EYQYASELIYDLKQLGDFCIGGACYPEGHTESANKEEDIKYLKEKVDAGCEFLTTQMFFD
NNILYNFLYRIREKGITVPVIAGIMPVTNGNQMKRICELSGTYLPTRFKAIVDKFGDTPD
AMKQAGIAYATDQIIDLVANGIRHIHVYSMNKPEVAAGIQANLSEIIK
>X5VQE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSHC422A00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A517ZGG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symmachiella dynata|TrEMBL
MRMRDIYSHGEFRLSIEIFPPKTEAGDAALFENLQRLVDYRPAFVSCTYGAGGSTRTRTI
DLCAEIQMRFALPATAHLTCVGATREELHQWLNEARQRGVKNIMALRGDAPAGAETFPHV
EGGLRHANELVELIRGELPDQGIGVAGYPEIHPEAPNADEDLVNLRRKVDAGADAVFTQL
FFANKHFFEFRRRYEQAGITVPLIPGIMPITNFERIKRITKMCGAAFPETLATKLEAAQD
DEQAQFDIGVEYAVGQCRELMDNGVPGIHFYALNKSKACEAILNALDYQTAT
>A0A2G6QUD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter sp|TrEMBL
MKITDHIKNAKGGTLFSFELIPPVKGRNIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIQHKYKVETVPHILCGGFTKEETEYVLIDCHYLGIENV
MALRGDARREQKYFEPTEGGHPYAVGLVEQINDLNHGKYLHEVIEKDEHADFCIGVAGYP
EKHLEAPSLQSDLKRLKEKVDAGADYIVTQMFFDNQRFFQFVEAARNMGITVPIIPGIKP
IAVKRHLQLLPQVFKIDLPQDLIDAVDACNNNKEVRQVGVEWAIQQSKELKEAGVPVLHY
YSMGKSDNIRAIAKNVF
>A0A3D5IWZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zunongwangia profunda|TrEMBL
MKVTEHIENAKGKTLFSFEIVPPQKGKNIQELYDNIDPLMEFNPPFIDVTTSREEHIYIK
REDGLLERKITRMRPGTVGICAAIKQKYDVDTIPHVLCGGFTKEETEYVLVDCHYLGIEN
VMALRGDAMKHQRYFEPTTGGHCYANELVGQIKDLSKGKYLNEVIDSDNHADFCVGVAGY
PEKHLESPSLETDLKKLKAKVDAGADYVVTQMFFNNQAYFEFVEKAKQMGINVPIIPGIK
PIAVKKHLQLLPHVFSIDLPQDLIDNVEACKNNKEVREVGIEWAIQQTKELKEAGVPVLH
FYSMGKSSNIKKIAEAVF
>S3UL28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira wolffii serovar Khorat str. Khorat-H2|TrEMBL
MKKILEIYKEARGPVYSFEFFPPKTEEGEEKLFEAVGELSKVDPGFITVTYGAGGSTRDK
TIRLTSELAKKYSLPAAAHFTCVGGNRDEIRTILAQIYDSGIRNLMALRGDPPKGEGQFR
KVEGGFGHANELISFIREEGFDFCIGGACYPEKHPEASSLEADVDRLKDKVEAGASYLVS
QLFFLNSSFGAFLDLVHKKGIHVPVIPGIMPITSFSQIERFKSMAACEFPPRLISDLEAV
KDNPSEFYKRSVDFSVAQCRELVETYRVPGVHLYTLNQSPASSDIVRKLKSS
>A0A0Q9QEU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Soil777|TrEMBL
MRNKRTAETMTRLLRHARYEVLPTASTEDKVLAHVPREVAVTVTASPGKGLEATLDLAER
LAGHGYAVVPHLAARMVAGRSELEEIVDRLTGKGISRVFVPGGDAEPAGDYLDALALLED
LALLGRPFSHVGITGYPESHPSIHDDLTVQSMWDKRRHATHIVSNLTFDASVVRDWLHRL
RARGVEMPLLLGVPGPVERTKLLTMATRIGVGESTKFLAKNKGLFARLAAPGGFTGETFL
EKCAPALGEPGALVEGLHVFTFNQIAETEAWRVELLDSLSR
>A0A4R1X4J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2568|TrEMBL
MGEGFELVCEVEPPTRPDLKKVRHQIGVLSPIADAFLIPDNHIGRATVSSVAVANEVQAM
GARGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVRGDEPTAGGRTSELTVRTMIEQAR
ATTFPGIKPFQVGAATGLRAVPRWKAEADFLYVQVSFSLENLLRWRESVELDIPVYAGVM
VLASAKMAQNLTAALPQIAIPDDLVAAVEADRDAGVDAACEQILGIRDSGAFDGVHLVPV
SRYRQVAARLERDL
>A0A0F2PXF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium BRH_c20a|TrEMBL
MENKFKDSLLDKDTMSVTWEVVPGRGAREKAQETALAQAESAAKGGKVHAVTITDNPGGN
PAILADYLGVEILKMGIEPLVHFTCKDKNRNQMESQLYSLDRAGVRNLLVMTGDYPVTGY
QGRPKPVFDLDPTHSLDLIREMNKGLEIQGPKGPSYNQNSDFYPGAAVSPFKATEAELVI
QYYKLKKKIKNGAQFIVTQLGYDARKFHEVLQFLKINNIDIPVVGNIYILPFGAARVMNG
NQIPGCVVPNKLLAEIDKERTAEDKGVGARLLRAAKMYAFMKGMGFAGVHIGGHGIKYEQ
VEYIIEKGEELSKNWQELISEFDYPQDNGFYYFEKDPTTGLNTDKPVNRKGRPLDAPVSM
AYSMMRMAHALAFEPGKPFFPLMQSIYKMRKDNKAHGLEHIIKVISNDCKDCGDCALLDL
AYLCPMSQCPKNQRNGACGGSYEGWCEAFPNEKQCVWVKAYARLKKHGEEEQLGSYCIPP
ANWNFYQTSSWYNFFLGLDHSAKRLGIKNPQPDNQGPNHNTKA
>A0A3M6QFN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Franklinella schreckenbergeri|TrEMBL
MPAPTPALPLSLEFFPPKTEAGALKLRQARQQLYALAPQFCSVTYGAGGSTQAGTFATVG
EILAEGQDAASHFSCIGAHAAKLRAELQELRDMGVKRLVALRGDLPSGYGISSGQAEQRF
QYASDLVAFVREETGAHFHIEVAAYPEMHPQAASPQKDLQAFAAKVRAGADSAITQYFFN
ADAYFRFVDEARALGVDVPIVPGIMPIMGASQLLRFSDACGAEVPRWIRTRLQALGDDVD
GIRAFGLDAVTALCERLIAGGAPGLHFYTMNQSPLVLEIAQRLGLHPSTPAAPTMPAA
>A0A2M7H5Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG15_BIG_FIL_POST_REV_8_21_14_020_46_15|TrEMBL
MSKLSEALQSGKFVVTGEVGPPKGVSVQEMLESAKLYKGRVAAVNVTDQQSAVMRLGSLA
VCHLLKEMGIEPIFQVTCRDRNRIAIQSDLLSAYVLGIENVLCLTGDYVTLGDHPKAKPV
FDLDSVSLLQAAVQLQQGKDLAGKELDGIPKFFLGATVTPGANPLEPQIIKMEKKVKAGA
QFFQTQAVFEPRKFEEFMQTVKHLNVPVLAGIILLKSAGMARFMNKNVAGVHVPDSLIEE
MEKAENRVDTSIEIAARLINELKGLCQGVHIMPIGWEKRVPAVLGAAGL
>A0A2N8TVT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cahuitamycinicus|TrEMBL
MALGTASIRSDHARTVRDMLAAGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSLDWDTDVRHFID
KCRAGADYAITQMFFQPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLERIGSLTNAAF
PAALKERILTAQDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSAQA
>A0A1X2I6I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Absidia repens|TrEMBL
MKVIDKINAAEKEGRLFWSFEYFPPKTAQGVQNLYDRMERMQRMGPEFIDVTWGAGGTSA
DLTTELVSTAQSVYGLETMMHLTCTNMPVEKIDNALKAAKECGCQNILALRGDPPKGQSN
WESCQNGFEHAVDLVKYIRQQYGDYFCIGVAGHPEGHSDCPDKEEDLLHLKEKVDAGADL
IVTQLFFDVDAFLDFVKRARAIGISCPILPGVFPIQNYTGLKRVISFSNNFVPQKIWDDL
EPLKEDDAAVKEYGINLTIEFIHKFQQAGINGFHIYTFNLERSTRLILERLNLVAPTESV
KPLPWLPALTQKRAKENVRPIFWKNRTKSYLQRTEFWDEFPNGRWGDSRSPAFGELDGWG
VSLKYSDEQCQEMWGQPETVDDIAVVFAKYCKGKIAGIPWSAQPLEAETETIRQRLAGIN
LLGYLSINSQPAVNGVKSSHSTYGWGPKNGYVYQKAYLEFFVSPAKLDDLIEKIGKDPNV
TYYAVNKQGDLRANTQSDHPNAVTWGVFPGKEVVQPTIVESTAFMAWKDEAFELWNEWAR
IYDRKTKSADLILDIANSWYLINIVHNDFQDEGGIWRLFDLEIDGEISRKIRQNGSDY
>A0A6B2ZQT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7909|TrEMBL
MALGTPSTRSDSAQSIRDLLSEGDRSYSFEFMPPRTPEAESGLWKAIRKLESLSPTFVSV
TYGAGGSTRGRTIKVTGRIAQETTLTPVAHLTAVDHSVAELRNILGHYADQGVRNILALR
GDPPGDPLGAWTRHPEGVCHAAELVALIKESGNFCVGVAAFPEMHPRSSDSASDLRHFID
KCRAGADYAITQMFFDVDAYLRFRDLVSAAGCDTPIIPEIMPVTTLRSLRRIPELSTAAF
PDELAGRMLAAESDPAAVRAIGIDHATEMCRRLIAEDAPGLHFMTMNFSTVTTEIYRNLG
LAP
>A0A5S5CDU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus methanolicus|TrEMBL
MFRESILNKKTGIITYGMTPPKASHTVEKIAEISQKQIERLRNVKLDALILYDVQEESDR
IEEERPFPYMAMLDPETYSEQYLQELDIPKIIYRCVGKYSEAELTHWLKRGEDKDRFSVF
VGASSSQQQVRLELADAYKLSRQHDGSLTFGGVIIPERHMKKNDEHLRVVNKIKQGCSFF
VSQATYNVEASKNFLSDYYHYCNDHELEMVPILFNLAPCGSTKTLEFMKWLGISIPRWLE
NELKYSTDVLDKSIRLTNKIFEELLEFGLEKGIPVGCSVESVSTRKVEIEASIQMVSDIK
AMIDKKSLVEMAG
>A0A2U1E343|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ezakiella coagulans|TrEMBL
MTKIQNIKFPLVFDGAMGTYYPDKSKRIMPECEMANLFDSEVIYEIHKEYVDAGAMAIKT
NTFQANTVSLGTDFSVVKNVIEAGLSLAKRAVKNTETLVFADIGPIPGHDENSIDEHKEI
IDIFLENGINDFLFETFSEIGTLKELAKYIKAKDENAFIITSFAVGADGLTRTGGVGEDL
LSEAAKSTDIDAVGFNCVSGPLRLREYIEKINLPEKIISIMPNGGYPTVIKNRTYYSANK
DYFSNATLQFLEYGVQIIGGCCGTRPEFIREITERISEYRYTKTRPEKKKHARLETPYTE
NLFRNKLEHGKKPIVVEFDPPKDLNMKRYMENVKALSNSGADGITIADCPVARVRVDASL
TAYKIKNEIGIEPIVHMTCRDRNVNASKALLLGLNLENILNIITITGDPVPTAEKDEVKS
VFQFNSTKFATLVSDMNEKVFTNKMNIGGALNLNANKFDLEIKRAQAKEKAGVNVFYTQP
VISKTAVENLKIARKELKSYIMGGVMPIVSYKNALFMNSEASGIRLDDEIIEQYKGLERE
EASRLAVEITSDFMRQIADYVDGYYIITPFSRVDIVGELIKLFKK
>A0A372ITN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidipila sp. 4G-K13|TrEMBL
MANRLHEVFGSRPVLCDGAMGTSLYARGIFINKCFDELNLSQPELVRSIHEEYLQAGAEV
IETNTFGANAFRLKRYGFQDQVEAINRAGARVARQAVEQLADKQAGTAYVAGAIGPLGIH
LEPLGKTSLEEARAAFTEQIRGLVAGGPGVGVDLLVIETMPALNEAEQALLAAKATAPDL
PVIVMVTVDEEANCLDGTTAELAAARLSALEPDAIGINCSVGPATVLTAVERMSEATTLP
LAVMPNAGMPRAVDGRNIYLCSPEYMASFARKFLKAGVQFIGGCCGTTPNHIRAMKSAVR
ALEAQKTSVQTTVKEAIVTETPPPPLAERSKIGRLIYEGTFVSMVEIVPPRGIDTRKELE
GAASLAALGVHAINVPDSPRASARMSAQSLCIQIQQHAGIETVLHYTCRDRNVLSIQSDL
LGASSIGLKNILCLTGDPPKLGNYPDATAVFDVDAIGLVNIVNRLNHGLDIGGNPIGAST
GFSIAVAANPGVPDIDNEIRRFAYKVEAGAEYAITQPVFDLRILEVFLKRIEEFRIPVVA
GIWPLTSLRNAEFMKNDLRVSVPDSILLRMQQASSPEQARAEGVRIAQEMIAAAKPMVQG
VQVSAPFGRYSAAAEVLVEVLAQKAKPVPVAANEGASVGQL
>A0A6A6PXR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neohortaea acidophila|TrEMBL
MHITKKLAAAHAEGRATYSFEYFPPKTAQGVQNLYDRMDRMHAFGPAFIDVTWGAGGRLS
NLTCEMIKVAQTTYGLETCMHLTCTDMEQSKLDDALTEAYNAGCTNILALRGDPPREKEK
WEQAEGGFRYARDLVKYIKQKYGDHFDVGVAGYPEGPDEDTNADEHIAYLKEKVDAGGTY
IITQMCYDADIFIEWAKKVRAAGIPDSVPIIPGIMPIQTHASFLRRANWTQCRVPPEWHE
KLEPVKNDDVAVREVGKDLIADFCRKLLDSGITMHLHFYTMNLAVSTRMVLEELAVTPSS
DSTDPTIKPLPWRQSLGRNRREENVRPIFWSGRKSSYVARTQDWDEFPNGRWGDSRSPAF
GGLDSYGIGLKGTNEHNRKLWGEPKTLRDISDLIENYMSGKVESLPWSEAPVSSETSELK
DDLIELNRRGFLTINSQPAVDGAKSSDPVFGWGPRNGYVYQKAYLELLITPKIIETVIER
MDADPDITYYAVNNSGVLRTNTSEDCGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFY
HLGSEWSKCYDENSEARHLIKDVTENWYLVNIVDNDFRRERGVFPLFDGLLVPELRADWV
QPKWTAPTTNGDVASTNGVQAETPHVNGVSSHDTGKPLTNGDLKN
>A0A077WW83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lichtheimia ramosa|TrEMBL
MKVIDKINKAESEGRLFYSFEYFPPKTPQGVQNLYDRMERMQRFGPEFIDITWGAGGTSA
DLTTELVATAQSVYGLETMMHLTCTNMPVEKIDAALKAAKDCGCQNILALRGDPPKGQKN
WESVENGFSHAVDLVRYIRKQYGDYFCIAVAGYPEGHIDNPDKEDDLRHLKEKVDAGADL
IVTQLFFDADVFINFVERCRAIGITCPILPGIFPIQNYNGLKRVISFSNNEVPQKIWDDL
EPIKDDDAAVKEYGINLTVEFVQKFRKAGVNGFHIYTFNLERSSRLILERLNLVPPLENV
KPLPWNPSLSSKRAKENVRPIFWKNRAKSYIRRTETWDEFPNGRWGDSRSPAFGELDGWG
VSLKYPQEECLKMWGEPKKADEIALLFAKYCKGDVAGIPWSAQQLEPETEIIRQRLAAIN
LLGFLTINSQPAVNGAKSSHKVYGWGPKNGYVFQKAYLEFFVSPDKLDELTAKISKDPQV
TYYAVNRQGDLRTNTQSDQPTAVTWGVFPGKEVIQPTIVEPMAFMAWKDEAYELWGEWAR
IYDRESESAKLILDIMNNWYLINIVHNDFQDENGIWRLFDLEVDQFADQSKHLLNGLVA
>M7NLU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paeniglutamicibacter gangotriensis Lz1y|TrEMBL
MSIGTTAAPPSLSYELYPPVNRDATEGVFTSIQALESTDPDYVSVTYSGSPARRNASLEL
IEHLIQNTRLRPLAHLTCVGESRETLQNLIRHFISLGVRGVLALRGDLPTDPEQWRGEYP
FARYLIELIRAVEADHSAALAGGRLGVGVAAYPIRHPESPSFEHDVEVLLAKERSGANYA
ITQVYFRADEYTNLVESARRAGVSIPIIPGVIPLNSVRRLNRLCAMAGIAPDPILAHALE
TASSDSERHRVGVDAAVNLARRAFDDGAPGVHLYTFNDHRGSLDVVEQLELPRTRARASN
AWATRAAV
>M7SPP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eutypa lata (strain UCR-EL1)|TrEMBL
MHIHDMIAEAEKSGQPSFSFEYFPPKTAQGVQNLYDRIERMYDFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYFGLETCMHLTCTDMGEEKVNDALAKAYKAGCTNILALRGDPPREKEK
WIATEDNFQYARDLVAHIRNKYGNHFGIGVAGYPEGCDDNKDEGQLLDHLKEKVDMGATF
IVTQMFYDADNFVRWMGKVRERGITVPILPGIMPIATYASFIRRANHMNCKVPDGWMEAL
EPIKNDDAAVRNVGKSLVADLCRKIMAAGIVHLHFYTMNLAQATRMVLEELDWMPTSNRP
RKQALPWKQSLSLGRREEDVRPIFWRNRNKSYISRTMDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKKWGEPQSVKDIANLFVRYIQEDLQTLPWSEAPLTAEADSIKEDLIK
LNQRGLLTVNSQPAVNGVKSSHSVHGWGPLNGYVYQKAYLELLVPPELFPEVLQRIHNHP
DLSYYAVTRTGTLKTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAYRLGKDW
AHCYDANTPSRVLIDKIMDEWYLVNIVNNDFHRPRTIFEVFEGLEVKDFDVAVQPGTNGV
RNGETNGEAHTNGSSVATTA
>A0A1M5WT33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium intestinale DSM 6191|TrEMBL
MFIKDIFKEKKVVFSFEIFPPKTTSSLDTIYKTIEDLKDLKPDFISVTYGAGGSTIDNKT
TLLSSLIKNKYGIESAAHLTCIGSSKSDIETILEDLKKNNIENILALRGDIPEDKTSNGE
FSYAYELISHIREHGDFGISAACYPEGHLECRDLDLDIVRLKQKVENGAEHLVSQLFFNN
NVFYDFLERCSKKSIDVPIEAGIMPVINKKQIERITALCGAELPEKFIKIMNKYEHNPEA
LRDAGIAYAVEQIVDLLSSGVRGIHLYTMNNPLVARRITESVGSIITSLNKDIIV
>A0A510KXW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia trevisanii|TrEMBL
MRIKDMFEKKEHLISFEIFPPNKNFSEEKLKNVTAELVECKPDFISVTYGAGGKTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEIHDYLQEAKNHNIKNILALRGDVPQGETEEIYN
KGDYKYASELISDLRKNSEFNDFSIGGAFYPETHYENNDLVDLFHLKNKVEAGTDFLTSQ
MFFDNDIFVKFKEQAEKLNIKVPLVAGIMPVTNAKQIKRIIELSKCSVPEKLDKLLQKYG
DSPESMKKAGILYASEQIIELLAYGIKGIHIYTMNKPEIAKEIMKNIEFAR
>A6EME3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|unidentified eubacterium SCB49|TrEMBL
MKVTDHIINAQGKTQFSFEILPPLKGQNISEIFNQMDPLMEFKPPFVDVTYHREEYVYKE
LENGLLQKKVVRKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLGFLGIDN
VMALRGDAVKTETYFAPEKNGHSYAGDLVRQISELNKGTYLDTEIENQAKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKQGATYIVTQMFFDNTKYFEFVKKCRDAGITVPIIPGLK
PLATKKQLNLIPHRFSLELPDPLISQVIKCKNNAAVRQVGVEWCIQQSKELIAAKVPVLH
YYSMGKSDNIKAIAADLF
>F0NRT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus (strain H10)|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSKEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTMNYTGTEVPGFWEH
>A0A0L6W639|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermincola ferriacetica|TrEMBL
MKAGSRLEKVLNAGHFAVTGEINPPQNAEGKVIAHHGEMLRDYCDAINLADNQTAVVRLS
SIASGIVLQQMGIEPNIHIVARDRNRIAIQSDVLGAAAFGIKNVLCLSGDHQTLGNHPTA
KNVYDIDSIQMLKMLDGMRKGYFANGEEIKGPRPELFLGCAANPFGDPFEYRVLRLAKKI
EAGADFVQTQSIFDMERFERWMEIVRAAGLHKKVKILAGVTPLRSWKAADFIKNKVAGMI
VDDRLIERLKAAKDPQEEGIKICVEQINYLKTMEGIAGVHIMAVAWEEIIPEIVKRANLY
PRPQIN
>A0A8I2AE64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVIDILTKSRSTLFSFELLPPLKGHTIDTVFDTIDRLKEFSPAYINITHHREDVVYMPN
TAGEPVPVKVRRRPGTISLAAAIHQRYGIDVVPHLICGGFDAHDIEDALIDLDFLGIQNI
LVLRGDADKISGRFEPKRGGHQHAVELVRQVQEFNRGIYLEKLIENPKESDFCIGVGGYP
EKHPEAPNIDVDIRHLKEKVDAGASYVVTQMFFDNAVYFKFVERCREAGIDVPIIPGIKP
ISAKEQLTNLPRVFNVNIPQALVQEVDRCADNRQVFDVGVEWAVAQSKELKAKGAPAIHF
YTMGRAENIARVAAKVF
>A0A5D4SJ47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sutcliffiella horikoshii|TrEMBL
MGILDSLAQDNILIADGAMGTLLYSYGSDCCFEELNLSQPNQIYNIHKAYLNAGANLIQT
NSYAANYHKLERYGLQDQVKEINSAAVRLAKKAVANHPDAHVVGTIGGIRAIKPEAIPLE
EIKRTFREQLYCLLLEGVDGILLETFYDLEELETVLKIARKETNLPIIAQVSLQEVGYLQ
NRVHITDALNRLELLGADIVGLNCRLGPYHMISTLEEVSIPKKAYLSAYPNASLPSYVDG
KLEYDSDAEYFKETALAFRDQGVRLLGGCCGTTPAHIQAFSRALQDVAPVKEKQVKRKER
TIIIPSKKKEVPTPLFEKAKKERSIIVELDPPRKLNTDKFMAGAKALKDAGIDALTLADN
SLASPRVCNTALGSIVKSDIGLRPLIHITCRDRNLIGLQSHLMGLHQLGIHDVLAVTGDP
TKVGDFPGASSVYDVTSFGLINMIKQFNQGVSLTGKELGEHTSFSVGAAFNPNVRVIDKA
VERLEKKIEAGADYFISQPVFSEEKLLEVHQATKHIDAPIYIGIMPLTSSRNANFLHHEV
PGIKLTPQVLEAMNRHQNDPQQASLEGLNIAKGLLDAALELFNGIYLITPFMRYELTVEL
ANYAKKYGRFHSSRRVQNV
>A0A7W2F5W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. LX47W|TrEMBL
MDNPNFSIEFFPPKTAEGADKLRVTRAKLSELHPKYFSVTFGAGGTTQRGTLDTVLEIMA
AGEQAAPHLSCVGGTRESIRAILAEFKANNIRRVVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPETHPQARSPQDDLLAFERKVKAGANAAITQYFYNADAYFQFMD
ECGKLGITVPVVPGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTALGQRLLAGGAPGLHFYSMNQAAPTTALWQRLV
>A0A1Q7KI90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon 13_1_40CM_3_50_5|TrEMBL
MKISFELNPPKIVKGDMFDLAQLNADMEAMADRALRLASLVSGIHLTDSVLGIPRVSSVT
AAGCIKNRVSTVKLSCSIRVRDRNFTSLCQAVSDAILIGIDSVLLLMGDDPADGLSDSGL
RPSAAVRMLRKEGYSSNIKLDLSFPAKVQDRAARSVRNKLEARPHSLVTQSISSVSDLGE
IVDLAKPHGIKVVAVVMVPVEKNRQSAAVIGLDWSQYERNPADFVRQAARIADTVLLTSP
NSFGSGLELLNELK
>A0A7X8GU98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVSELIDKAKKTAFSIELLPPLKGNSIQQIFRTIDRLKEFDPKFINITTHHSENIYKED
VQGVYRKMNVRRRPGSVAIAAAIQNRYGIRAIPHIISRGFTREETEYALIDLSFLGVTDL
LLLRGDIKKLDAEQRAMDSHPYATGLQEQVNNFNKGIGFDGSSFTPPEEPFSYGMACYPE
KHEESPNMESEIFYTKMKVDNGADYLVTQMFFDNRKYFEFVDRCRAAGITVPIIPGIKPI
HLRNQLTVLPKIFGSDIPEELAEALRECTSDEDAKEVGVEWCIQQCKELVQSGVPSIHFY
TLMATESVHRVAREIY
>A0A6L8TXG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSCIKPARRWQPRFYPFRRESFRKRFREKIEIMLKGPLWGCRMCGNCLLQETAFICCMEC
PKGLRNGPCGGVTPDGHCYVDPTRRCVWHAIYNRARKTGRTDTLIEVLPPLDWSRTGGET
WADVISQIGKVGSGKFFGSLFSHDREYRKQVWDSVFMTIRQPAWWNGDREYHPAAYTEPA
SELERSLREGRFVVATEITPPLSSDTEKLRKAIEEVRPYVQAINFTDASSAIPRMSALAC
CKVATDLNAEPVFQITARDSTRLSLQGDAIGAGQFGIRNILCITGDSPLVGNPPISDMNI
YDLDAVQMLWILRRMRDEGIYLDGRKMKHPPRYFLGAATTPGALDPELQAIRDQKKVNAG
AQFFQTNIIFDAEKLDPWLEQLDKRNVLGKVSILAGLAPLKSYKTALYLHEKVPGVYLPD
KILNRMEKAGDGAREEGIAIALELIASLKRKKGISGIHLMTLGGEDIIGRIVREAGLDR
>A0A7K3WR17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorpha ignava|TrEMBL
MKITEHLQNSKKTLFSFEILPPLKGKRIDDIFEGIDPLMEFNPPFINVTYHREEYVYKKF
PNDLLKKISIRKRPGTVGICAAIMNKYDIDAVPHLICGGFSVEETENALIDLQFLGIDNV
LALRGDAINGESTFKPEENGHRYAVDLITQISDMNKGKLLHEESQHSAKSLFCIGTAGYP
EKHYESMSMKTDLTYLKHKVDAGADYITTQMFFDNKKYFDFVDRCRAIGINVPIIPGLKP
ITKLRHIAFLPKTFYVDFPDELADALVKCKTDAEVNKVGIKWAIKQSQELVDANAPCIHF
YTMGKSESVKAIATEVFGK
>A0A7Y5LH47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacteraceae bacterium|TrEMBL
MTTSTSPAAKSRAIEFRKRLQEKALVADGAMGTMLYSRGVFINRCYDELNLSAPAMVKEI
HEQYVKAGAELLETNTFGANRMRLGAFGLAERLRAINEAGVRVAREAAGESAFVAGAIGP
LGARIEPLGPTSFSEARDIFAEHARALTEAGVDLLLLETFSDLNELREAALAAREAAGPD
MVIAAQVTIDDYGNLAGGTTTEQFTRRMDEFPVDTLGLNCSAGPRVMLETIEKMAKFSAK
PLSAMPNAGHPATVEGRKIYLCSPEYMAQYARRFLWAGVKIIGGCCGTTPEHIRAIRSEA
RSLQPAIRKIAVTVETPAENQKIFKNVPVAEKSKLGAKLAAGRFAAFVEILPPRGVDASK
EIAGAKACAEQGIDCINVPDGPRASARMSAQVTCQLIQQHAGIEAVLHFCCRDRNILGIQ
SELLGAHAVGIRNLICITGDPPRMGGYPDATAVFDVDAIGLTNIVSGLNRGLDIGGNPMG
SQTQLLIGVGANPGAFNLEEELRRFEWKVEAGAEYAVTQPVFDLNLLEQFLKKTEHLHIP
FIAGIWPLTSYRNAEFMVNELRVPVPEQFMERMRRVESAEQARQEGVLIAQEMVQKVRPM
VAGVQLSAPFGRYQMAIEVAQAIGAR
>A0A419FFW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium|TrEMBL
MEEKFLRKLAAGVVLGDGAMGTQLYERGVYINRNYDHLNLTDSHLIKAVHREYIEAGAEI
IETNTFGANPQKLAKFGFSEEAFAINQAGAEIARRCADEAAGVLVAGSMGPMGKPIAPVG
TISEEEACAAFGLQAQGLLAGKVDLFILETFVDLQEIRLAVRALRRLTELPIVACMTINE
TGQTIYGISPEEIARELSALPVQVIGLNCSTGPQTILEGIVRMRGETDLPLAAFPNAGEP
EMVESRILYLSTPEYFAEYTKRMIQNGVQFVGGCCGTTPRHIRFMASAVRALYPASEKQE
VLVSTARESKLEAVEVELAPRAQRSPLGQMLDDAAFPVSCELNPPRSSSVDKILQQVRLL
QKAGMNVVNIPDGPRASARMSPMILAHIITRETGMEAILHYACRDRNILGMQSDLLGAGA
LGLRNILAVTGDPPKLGDYPMATAVFDVDAIGLLRIADHLNHSRDLAGKPITHPTAFFLG
AGFNPGAIDLALEVDRLHQKIEAGAEYILTQPVFDSEKLLAALNKAGNIEVPVFVGILPL
ASYRNAEFFQNEVPGMDVPLAIRERMRAASEQSKEHGMAEGVAIARESLAAVKDYVQGAY
IMPPLSKVELAVETAAILPGHRDMAEVSRLLADEEPMKKGA
>A0A2N3CAP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HGW-Alphaproteobacteria-18|TrEMBL
MNRPAIQSQTARDPVRVSFEFFPPKSEAMNARLWETVQRLEPMSPAFVSVTYGAGGSTRE
RTHDTVRRIATETALRPAAHLTCVSATKEEVLAVAEEYWQAGVKHIVALRGDPPAGMGAK
FEAHPGGFADSVDLIRGLREHRPELGKCFEISVSCYPELHPESRGWDAEIAFLKAKQDAG
ADRAITQFFFEPDTYLAFLDKARAGGVTMPIVPGIMLQPNFNGLKRIAGLCGSSIPAWLH
TLYDGLDEDEETRDLVTANVAADLCRKLQAEGVQDFHFYTLNRAGLALSTCRLLGITPQS
AKAA
>A0A3A8FGX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WCHAc060007|TrEMBL
MSKNLPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIKRFCDKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A3C0QTS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MTIPELITRNNGHPRISFELLPPVKGSSISTIFSMLDQLMAFQPPFINITYHREEISYVK
QADGSLKPSVVRKRPGTVGIAAAIQARYKVDVVPHIICGGFSSQDTEDALIDLDFLGIRN
LLVVRGDADKITGRFNPNPQGHRYASGLIDQIMNMNRGIYHDQCIENPSRTNFSIGVAGY
PEKHPESPNAEEDLFYLKQKVDKGAEYIVSQMFYDNEVFFNFVKRCRDAGIQVPIIPGLK
PLSIREHFHLLPRTFHLTIPPALVKEVNQCKDNKMVRELGIEWTVQQIKELRDAGHPFVH
LYTMGKVDNIVKISEKVL
>A0A221R448|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinomonas sp. R1AF57|TrEMBL
MTRQTLTAPPRTSASTEPLRTRLEIVPTEEIVPAIATTVPQGTALTVTCLPHHGIEATAQ
AAVRLAGLGYSVVPHLAARSIVDRSRLAKTLRDFESAGIEEVFAISGDAVRPAGPYATSL
DLMEDIADLTGGRLAIGIAGYPEGHPQRTAVELLDSLLAKQHLAANVVTQMCFSAPAITA
FAALLRQEGLDLPVWAGVPGRVPRARLISLAAKIGVGPSLKFISRKGPLARRLLSGDAYS
SERLIGELSASRAGLAGIHLFTFNNLGLV
>A0A2E6DDY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium|TrEMBL
MKIQEILQEVRPXFSFEFFPPKDDDGFDQLFQTIDRLKSWNPAFVSVTYGAGGSTRSKTI
DLVGRIKNEIGLESMAHLTCVGHSSDEICSVLKSLQEQGIDNVLALRGDPPQGETNFVKP
ENGFGFASELVGFTRDKFPFCIGVAGYPEGXPECPDHRQGLXHVKNKIIAGGSFIVTQLF
FDNKVYFDFVKNLKDIEVDVPVIPGIMPILNLKQIKRFTKMCGATVPADLLARLESVQDD
PEAVREIGIDHATAQCENLLSQGAPGIHFYTLNRSRATLSVLERLKSISIGS
>A0A2W0C4W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus illinoisensis|TrEMBL
MGKNGKRVITILLAGCLIAVALPRAVDLDQLYAASDTSDISTTKDLRQTLLTAMSQRTEE
LVFTYKGDVKGLKKQLQSSIDEAMTSDPYIQYTVKSYAFNYKGSNVSAEVHVNLSYRETK
EQTDYVNRKVTHVLKEIITPGMTNHEKVKAIHDWIVLHLAYDTSLQKYTAYDGLVTGSTV
CQGYSLLAYRMLEQVGIENRIVEGTAGDQLHAWNIVKLDGKWYHMDTTWDDPTPDRKGKV
SHNYYLLSDDEMARDHIWTGKGKYPTAPAPYREALQTLIQSGGSKAPAYQKLYHALEYSL
YDEKDAVSGHSALETKVQSVLKEGGTTLTFRYKGTETSLVEDLQNLYQLGMKSISYYVSK
MEDTTDLRVKINWTL
>A0A0V1PDW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella sp. T8|TrEMBL
LASILKKILFLSLMASLEAVELKATRHDLNSAAKKSTDEIYRPLIDRIKENISNGRRFFS
LEFFPPHTTEGLINLLKRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCILNFCL
LDTMLHITSVQYDEKTVLFNLERAKKIGIRNILALRGDISDDANVTTTDFQYACQLVRFI
RSHYGDYFTICVAEDLLNLKAKVDAGADFIITQLFFNEMHYFKFVSDCRKIGIVVPIIPG
ILPIQSYQSIMKIVQLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRKLLNREHH
VVPGLHFYTLNQEKSILEQIGFWKKAPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYL
CRTRDWKQFPHSRWSDVGNPAFGDLKHYLFSCIDQMDDSCALDMWDKELSTLEHVRDIFC
NFIARTPNRHGHSVRRLPWNENHLDPATDVLKNELIYYNSNGILTINCQAAVNGLPSSDP
IFGWGEANGYIYQKGYLEFFASSTCTTILLNHVQNFPSINYHAINFDGSFETFNYDEDAT
VALTWGVFMGQEIVQPTVANAASFRVWKVVAQLSFIQSFLFVFEQDEAFDLWQRWAGLYE
SGSIGRKLLQRIHDDYRLITLIDNDYPQPCSLSALLRAVISDYIGGKNLTTDDDRLACRL
ALRASKHGITAEKEEEEEAIIE
>A0A561BX81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella amoyensis|TrEMBL
MVNGLPSTRPGSTPTIRELLGSGDRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGAGVRNVLALR
GDPPGGPTKPWVAHPEGLNHAIELVELVRELGDFCVGVAAFPDKHPEASDLDFDARMLAA
KAKAGADYAITQMFFGADDYFQLVDRAAAYGCDIPILPGVMPVTNIKQIKRMAELTGMAL
PTAVTDRLHAVEEDPAAVRAAGIEIASELCDRLLEGGAPGIHFITLNRSTATRQVYLNLQ
GTTV
>A0A8H9PLQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyvera intermedia|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRAIAKDYWDNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCASTGIDVEIIPGILPVTNFKQAKKFADMTNVRIPAWMSQMFE
GLDGDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A3L6JNZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MHVLESNDFVVTSEIGPPRGADKTLVLERTRLVMDYCDAINITDNIRGIPSMSSATCAHF
VLDAGAEPIMQMSTRDRNRISIQSELYSAYALGIRNILFITGDHTLLGSHPEAKTVYDID
SIQALGLASHLMGGTDLAGDKLEGTPEFFLGSTFNPYADPLELHVIRAEKKRDAGAKFFQ
TQAIFDTARLETFMDKAADLKLRVLAGITPLKGPIMANFMNKSVPGIKIPEEVIKRLEAA
GRGLKGEKKREATRAEGLLIATEVIRAVRRIKGIHGVHLMGIDWEESIPEIVKSAGLYPR
PEVR
>A0A1S1YH55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus oceanisediminis|TrEMBL
MNFLNKLKNEIIIADGAMGTLLYSYGTDSCFEELNLSQSEQIQHIHEAYIGAGAELIQTN
TYAANYLKLQRYGLEDSVKAINSAAARIAKKAAKERAYVAGTIGGIRGFKPNMITLEEIK
RSFREQLYCLLLENVDGILLETYYDLEELETVLAIARKETDLPIIAQVSLQEAGVLQNQT
SIADALAKLEGIGADVVGINCRLGPHHMLKTLESVPLSKHAYLSAYPNASIPAYTDGKFH
YEGDAEYFRQSAIEFRNQGVRLLGGCCGTTPDHIKAFSEVLKGLPPIEEKETKAINKVMV
SEKPSSSRELPPLQDIVRERPSVIVELDPPRKLDTSRFFEGAKALKEAGIDSITLADNSL
ASPRVCNSALGYLVKQQTGLRPLVHVTCRDRNIIGLQSHLMGLHALGLNDILAVTGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSFSGKDLGQKSAFSVAGAFNPNVRSLEKAVG
RLEKKIEHGADYFISQPVFSEEKLLEVHEAVKDLKAPVYIGLMPLTGSRNAEFLHNEVPG
IKISDSIRNRMASLKDDPAQAGAEGIAIAKSLIDAAAELFNGIYLITPFMRYEMTVELSN
YARETTERLSRRKQHA
>A0A1C2AUS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacteraceae bacterium GOM-A3|TrEMBL
MNFSLEIGPHTDLDTLPEVKDVYVTMLPGVDYKETADKSGDLVKKGFNPVPHFPARSINN
EEELKDYISRCKDLGVKQILAIGGSRDPVGKFDSSYQILETGLFDGIKIGIAGHPEGSPD
ISDSELEKAMIDKKPYADYIVTQWLLDSKPIVDFISKQTIPVHVGITGPMKISSLIKFAN
IVGAKNSINFLKSNFTKALDLLKPKDPNDLIGKVKSHTDYFHIYTFGGLKETNKWLKENN
YV
>F8MJ09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neurospora tetrasperma (strain FGSC 2508 / ATCC MYA-4615 / P0657)|TrEMBL
MHIREMLADAERTKAPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIA
ELTCEMVAQAQAYLGLETCMHLTCTDMGEEKVNNALQRAYKAGCTNILALRGDPPREKER
WEAAEGGFQYARDLVAHIRKLYGDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGASF
IVTQMFYDVDNFLRWVKRVRERGITIPIIPGIMPIATYASFIRRANHMNCKIPEEWMAKL
EPVKNDDVAVREIGKTLVAEMCRKIVDAGIRHLHFYTMNLAQATRMVLEELDWLPSPNRP
LKRALPWKQSLGSGRRDEDVRPIFWRNRNKSYITRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNELNRKKWGEPQTVKDIANLFVRYLNQELEYLPWSEAPISSEAELIKDDLIA
LNNRGLITINSQPAVNGVKSTHPVHGWGPANGYVYQKAYLELLVSPELFPEIKRRIEDHP
DITYYAVTKSGNLHTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGLEW
ARCYDADTPSRLLIEDIMNKWYLINIVNNDFHQPRTIFEILNDLSLPDLEKVYTPAHTNG
ATNGVSEASTVPQ
>A0A1Q4DJC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 64-17|TrEMBL
MRVSFEFFPPKTEDMERSLWEAIRRLAPLSPHFVSVTYGAGGSTRERTHSTVKRLINETA
LKPAAHLTCVDAVRGDVDQVVRDYHAAGVRHIVALRGDPAGGLGAAFTPHPGGYRNAADL
VSGIKRIADFEVSVSAYPEKHPESASVDADIDMLKAKVDAGATRAITQFFFENDLYFRYL
DRVRARGIDIPIVPGILPVQNFKAATTFATRAGASVPGWLAQRFDGLDDDPATRKLIAAA
VAAEQVLDLVERGVSDFHFYTMNRADLVYAICHLLGVRPPQPVKAKAEAA
>A0A1L9GNV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. MWH-Adler-W8|TrEMBL
MELSVEFFPPKTPEGETKLHLVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
SETGDWFHIDVAAYPETHPQAKSPASDIDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YELGVTQPIIAGIMPITNSSQLLRFSDACGAEIPRWIRLRLQSYGDDVASIRAFGEEVVT
DLCDQLLTAGAPGIHFYSLNQADAVLAIADNLDLTK
>A0A257NPW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidocella sp. 20-63-7|TrEMBL
MTQLSNRDTLERWASGERIAPLPARDGAAPPAVSFEFFPPKTPTLEAQLWACVERLATLA
PDFVSVTYGAGGSTQERTHATVLRLVRETSLTPAAHLTCVGASREEVDEVARRYWEAGVR
HIVALRGDMPNGAAYEAHPGGYAFAADLVAGLKRVADFEITVAAYPETHPQAISPEADLD
NLKRKLDAGATRAITQVFFDNDVYLRFLDRAIAAGIKAPIVPGIMPVSNFGQAARFCASC
GTSVPKWMESLFEGLDDDIETRRMVAAATTAEQVRILQANGVDEFHFYTLNRPDLVYAIA
RILGVKPRAIGA
>A0A4Q6XYI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas populi|TrEMBL
MTISVSQLEEARRALEGPLFADVAGDTAVSFEFFPPKTPKMEEALWETVKTLEPFGPRFV
SVTYGAGGSTRERTHATVARIQAETAMPAAAHLTCVEASKAEIDAIADAYWQAGVRHIVA
LRGDAPGADGFVPHPDGYTNAADLVAGLKRLHPFEISVAAYPECHPDSRGVSDDLDNLKR
KIDAGATRGITQFFFEPETFFRFRDRAVAAGITAEMVPGIMPVTNFASIVKMSALCGTEV
PAWLGRLFEGLEDHATARQLIAATLAAELCRKLYAGDVRTLHFYTLNRAELSFAICHMLG
LRAKVPAKVAVAA
>A0A4R6S7X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labedaea rhizosphaerae|TrEMBL
MTSVLERISVGRPVFSVEFFPPRDEADQQILGRAIRELESLDPAFVSVTYGAGGKSRRGT
IEATRLIAEETTMTPMAHLTAVDHSVAELRNMIGWYAAVGVRNILAVRGDPPGDPYGDWI
AHPQGLNYAEDLVRLVRSLGDFCVGVAAFPYGHPRSADLDTDTRHLIAKFRAGAHFAIAQ
LFFEPDDFLRLRDRVATVDPDALLLPSVMPLTTVRTLHKTAELAGVDVPAWIAERMDPLA
GDPAGFRAAGIDLVTNLCERLLAEGVPGLHFITMNRSKATREVVARLGLLPTRA
>A0A3N9X149|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora globispora|TrEMBL
MALGLPSVLPNPQPAIGALIRDGQPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVELTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVPHPEGVRYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCQAGAEFAITQMFFDADDYLRLRDRVASAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFERVADDPEAVRRLGIEQASEMCARLLDEGVPGIHFITLNRSTATREVWQHLR
ADARV
>A0A0L8PA46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces antibioticus|TrEMBL
MDPALLDDFSLEMTGKDVPGLEEACDSVPSGTRINITFLAGEDTRTRLAAARAVKRLGFV
PVPHISARRLPSRPALEEFLAGLAADGTAGNVFVVGGDPARPEGPYEDALAVLRTGLLRR
HGVRHVGIAGYPEGHPGIADRALWSALTDKAAAIGAGRFTGDVITQFGFDVDPVLAWLEA
LRARGVHLPVRVGVPGPAGVRRLLRYAGRFGVGTSASVARKYGFSLTNLMGTAGPDRFLT
ALADRYDPARHGTVKVHFYTFGGLRATADWITRFRHESERSDEVRQTARS
>A0A368TWI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas montanilacus|TrEMBL
MSTQAHPLGISYEFFPPNTDLGREKLMGVRDALAERNPRFFSVTYGAGGSTQARTISTVQ
AVRESGITTAPHISCIGSEKAQLRDLLHRYREQGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPECHPQAPSFEKDLENFVRKMKAGANLAVTQYFYTADAYF
HFVERTRALGVESPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSESIAAF
GEEVVSRLCQRLLDGGAPGLHFYTLNQAAPSLRILDNLS
>A0A520J4H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKITDHIKNAQGKTLFSFELLPPMKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVSYRKRPSTVATCAAIMNKYRVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDASFIPTPDGHAYASELLQHVVDMNNGKYLHEHIDNSEKTDFCIGIAGY
PEKHFEAPNLQTDFKYLKLKVDLGAEFIVTQMFFDVNAYKTFVEKCREHGINVPIIPGLK
PITSSKQLISLPKTFHLDIPMELSEAITACSTEAAVREVGIEWMIEQCKQLKAIGAPVLH
FYTMGKSGPTRQIAQAIF
>A0A1E4G7R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterium sp. SCN 64-44|TrEMBL
MLDDNLRASRKTADQRPELQLSFEFFPPKTDAMEERFWESIHKLAPLHPRFVSVTYGAGG
STRERTLRMVSRIKADTGVAAAAHLTCVGATRAEVDEVVRGYQAAGVSRIVALRGDPPEG
VGQPFTPHPEGYQNAADLVAGIRRLGDFDISVAAYPEKHPQSADWGADIDNLKRKLDAGA
DRAITQMFFSNADYLRYVERARKAGIAAPIVPGIQPIHSFRQISGFAARCGASIPAWLAE
RFEGLDEDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRP
>A0A239UJ28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus piscifermentans|TrEMBL
MNRFLQTLKENVLVADGAIGTILYSEGIDTCPEAYNLTHPHKIERIHRSYIQAGADVIQT
NTYGANFEKLQTFGLEHRVKDITRAGVRIAKKAADEDTFILGTVGGFKGVQQNELSLSTI
LYHTDIQIETLIDEGVDALLFETYYDLNELLQVIRATKKKYDIPVIAQLTASNTNYLQDG
TEINEALKQVEAEGADVIGLNCHHGPHHMQQSFTHIELPQHALLSCYPNASLLDFENSSI
KYSDNATYFGKVAKSLVKEGVHLIGGCCGTTPEHIHYIKEAVEGLKPINEKKVIPIRRKS
NHPSIPVQKDNLTTKVKAGPTVIVELDTPKHLDTTKFFANVTKLDKAKVDAITLADNSLA
TVRVSNIAAASIIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKV
GHLPGATNVYDVNSKGLTELAVRFNQGLNIDGGALKTTTNFNIAGAFNPNVRKMEAAVRR
LDKKVDSGMNYFITQPVYTVERIQEIAEKTAHLDAPFFIGIMPITSYRNAQFLHNEVPGI
TLPEEILEQFEAVQHDKQKTKELSLKICRELVDEVTKHFNGLYLITPFEQVDYSLELATY
FKSKTESNQEAII
>A0A7Z3CK38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SK|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKAELRTLLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A443XQ74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAKDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A2N8FWQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FW305-130|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFETDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A503LBF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-4-16|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDTVIREFADMGVKRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A4R8TTC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum sidae|TrEMBL
MDKITDKIAALPADANYFSLEFFPPKTQMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRTLIDKALEDAKALGIRNILALRGDPPRKDE
YRTADDSDVEDMDDFVWAIDLVRYIRKKYGDYFCIGVAAYPEGHADESHPLGQSFEHDLP
YLVDKVQAGADFIMTQLFFDIKAYDNFERVLREHPSGAFKTIPLLPGLMPIQSYQMIKRT
TKLSHAKVPADLMARLDAAKGDDERVKRVGVDILSELVQQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDADEDEEAVIDDAIGVPTVQLNGLSPIPPSTPRTFSGRRQSSIG
SDPHNRVIVSSASNPAYEITAASLSAEPVNTRANTLAISEGEGVLGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHMSVTQAVGLWGTPKTVQDVNNLFIRHIKGQLSAIPWSEEELL
PESNIIQQELLGLNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVEFFLPSAD
WASLVARLNEVTDNTICFYAANAAGDFVSSDASGGLVLEGTECSTNAVTWGVFPGKEIIT
PTIIEEVSFRAWADEAFKIWGEWAKVYGKGSESEALLERIQSDYWLVNVIHHDYVERDAL
WQLLNGEKET
>A0A330GDB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A3Q8ZEZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7D.F.Ca.US.005.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEGRLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETAIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFRQVANFSARAGAHVPGWLVERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
GSAAA
>A0A517TCM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calycomorphotria hydatis|TrEMBL
MLINELYQSGEFGLSIEIFPPKTEKGDASLHGTLERVAKFSPAFISCTYGAGGTTRDRTI
DWCRAIGQTYKLPATAHFTCVGSTREELLAWLERAREVGVRNIMALRGDAPEGQDEFVAV
EGGCRYANELVELIKGQYDDMGIGVAGYPEKHPEAPSAEVDLQNLKRKVDAGADAVFTQL
FFVNENFYRFRDAAANLGIEKPIIPGIMPVTSFERIKRITSLCGATFPKELAEPLEAAKD
DKDAQFEIGVSYAVKQCRQLIDAGVPGIHFYVLNQSQAAERILEDLGLMPQAVA
>A0A843A126|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MSYRSNLEKILSEGRFVVTAEIGPPKGSDAKKIRDKAEIVRGSANAFNITDNQTAVVRMS
SLAGCVILLQMDLEPIMQMTCRDRNRIGLQSDVLGAAALGVRNILCLTGDHQSFGNHPAA
KGVFDVDSIQLLQIIKNMRDAGVFQSGDPLLAERPSVFLGAAANPYADPFEIQVDRLRKK
IDAGAEFIQTQSVYNVEKFARWMDDVQSQGLDKKVHILAGITPLKSVRMAERMKFHVPGT
DVPDVVYQRMKNASDPAKEGYTIALETIRELKILPGIHGIHITALFWEEIIPALVKDAGL
FHQI
>A0A7J4P768|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MEVIRQFKEILKKKEIPITYEIYSPRGYKVNQFIDSLSSFKDKVDAITVPDNPLATLKIS
PIAYAHLIKRSLKIDVIPHLACRDRNSLALQSELLGAHLLEIRNLFVTTGDRAAESKGKK
EVREVNSIGLCKIIKLMNEGLSPSGEKFESSERTDFLVGGAIIFGRKNETNVLSKKVDAG
FDFFLSQIIYSAEEVINFFNQIEAQGXXILKMPSFKISAEIREKLVKSTDIAETSRELCL
EVAGQLKNELTPKYKIGFHLMPFGDDLLGERIIKEIR
>A0A1H9ILQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amphritea atlantica|TrEMBL
MHIVQPDNTAAIEKSPSAAAYTLEVTGKEIRQIEIAAPLIPPGTPINIAFLGNENPDQRV
NAARVIRECGFEPVPIISSRRLRSEEDLNSLITQLNRAACPSRYIFVGGDPATPAGPYTD
SLALLASGVLQRHDIHHVGIVGYPDGHPKISTDKLWHALEWKYQLLRDAHCTLEITTQFG
FDTEAIVRWIRQLRDRGIDAPVNIGVPGPASISQLLRYAKQFGVVASTEIAGRYGLSLAT
LLRKSVADHFWADLVRGLAEKELGDIGYHLYPFGGIKDGVRWMNSRVCNDQPLADSSGLE
V
>A0A258UJQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilales bacterium 16-45-7|TrEMBL
MTQPITYSFEFFPPKTVEGIANLREARLALAKYKPEFFSVTFGAGGSTRDRTMDTVFEIQ
AEGYAAAPHISCISSSKEEICELLNAY
>A0A0K9ND92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea sp. D27|TrEMBL
MDKITSRGEQMKIKEILKDEEPHISFEVFPPKTDAGYESVLSATEKIAALKPSFISVTYG
AGGGTSKNTVNIASHIQNDLGVVSLAHLTCASSTKDEVRQVIGKLKDEGIENVLGLRGDI
PEDVQFPVSNQYKYAFELIQDIKSQGSFCVGAACYPEGHVETEHKKDDIENLKNKVECGV
DFLTTQMFFDNNILYNFLYRIREKGITVPVLPGIMPVTNSKQMKRICSLSGTALPERFRA
IVDRFGDNPKAMQQAGIAYATDQIIDLIANGINNIHIYSMNKPEVAEAIMYNLSEIVKV
>A0A495QNN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura pelletieri DSM 43383|TrEMBL
MPRLRPARPPAVRELLASGAPSFSFEFFPPKTDKGARNLWRTIRELESLHPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVDHSQAELRNLIGRFAAVGVRNVLALRGDPP
GDPMGEWVKHPEGVEYASDLVRMIRSYGDFCVGVAAFPYKHPRSPDIESDTRFFIEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDVPILPGIMPVTQISTIERSEQLSGAPFPPEV
KARFDAVADDPDAVRRLGIEHAAELSRELLEQDAPGIHFITFNKSTATREVYGLLDGAGY
AASGSVPPMTA
>A0A1E5RGD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hanseniaspora osmophila|TrEMBL
MRISEKLQKHKEKYPDKPTFSYEYFVPKTSQGAQNLYDRMDRMYELTGPQFIDITWNAGG
KKVEKKPIVQNGXSTNGSSTKTNEXVSSFNGFRADAKPTTTDIIETCQTVLGLETCMHLT
CTNMPLSEIDEALQKAYDSGCQNILALRGDPPLNGGDNGDDFTGDGDDASCFQYAKDLVK
YIREKYGDHFDIGVAAYPEGHPEESNRELLLDFLYEKVECGADFMITQMFYDADIFIDWC
AKVRARGITIPIIPGIMPITSYDAFLRRAKWCQINIPKQFLKELDPYQEDDQMVREIGTK
LVVEMCMKLLQSKYVTHLHMYTMNLEKGSMVILQKIGALRKNQNTLSSNQLWRRSLNPQR
KNEAVRPIFWQRRPYSYVARTSQWGADEFPNGRFGDPNSPAFGGLDLAGAQLIRQTGKRC
LELWSQPTKVKDISDLIINYLNGDLKCLPWSDTPITGEVDSILHYLKNLNKKSIFTINSQ
PKVNGLPSSDKIFGWGPKNGFVYQKGYLEFLLPKDKINQFLELANNNEELTFFLLNNDNS
IFYHKDGENGTVNESVDYNSETSTNSTTAENGDVSPSSSSKSSSLSPIGQTENGNKKRKV
ERKKSCDTDNLSVSRANAVTWGIFPGREVLQPTIVEKESFVAWRDEFYQILQEWKLNFHK
FNAPESATLIGKIIDDYVLCNIVDNNFVSPENQIYSLLSELGE
>A0A0S8FZE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonas sp. SG8_38_2|TrEMBL
ILPSKGCDPTDVLEKVRQLREAGVDAVNVPDGPRAMMRMGVLASCSIIEREVGLETIPHY
CCRDRNLLGMMSDLLGAHALGLRNLLIITGDPPKMGPYPDASAVFDIDSVGLTNLVRKLN
QGLDPSDNSLGSQTSFFIGVGVNHASVDPEYEIHHFEWKVDAGAEFAVTQPIFDVKQFLE
FLERIEHVRIPTVAAIWPLVSYRNAEFLNNEVPGVVVPETVLERMRLASERSKEEGMAEG
LAVAREMVAELESHVQGVQVSAPFGKVDFALQVFDALSDWGGFQAEALP
>A3WED2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. NAP1|TrEMBL
MTPTLNQLHEAKTALDAPLFSDLPGDIDISFEFFPPKTEKMGETLWSSVATLSPLGPRFV
SVTYGAGGSTRERTHEQVVRIQNEAGIPAAAHLTCVNATKEEVNEVARHYWEEGIRHIVA
LRGDPPDGASAYTPHPGGYENAADLIAGLKKVADFEISVAAYPEVHPDSPDAQADIENLK
AKFGAGADRAITQFFFDPECFFRFRDEVAAAGIEAEVVPGIMPVMSFAAVQRMSAMCGTA
IPSWMEGLFDGLDERPAARQLVSATIAAELCRKLYAGGVRQFHFYTLNRAELSYAICHML
GKRPAGEAA
>G2IXB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogulbenkiania sp. (strain NH8B)|TrEMBL
MSTKPRTFSFEFFPPKTAESIAKLRTTRQQLAQFKPEFFSVTFGAGGTTREGTLGTVLEI
RNEGYAAAPHLSCIGSTRDNIRAILNEYRSHGIRHIVALRGDLPSGMGEAGEFRYANELV
AFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLNNFVRKVQAGANSAMTQYFFNADAYFRF
VDEVQARGVDIPIVPGIMPIANFGQLCRFSDMCGAEVPRWLRLRMQAYYDDTASIRALGL
DVVTELCDRLLTGGAPGLHFYTLNQAGIVSTIWQRLGL
>A0A444JBT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electrothrix marina|TrEMBL
MKSGSNLERVLRSGAFAVTGELGPPKNSDPDVVREKARILKGNVDAVNITDCQTAIVRMS
SIGAGLLAQAEGVEPVIQMTCRDRNRIGMQSDLLAASALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMVRDMRDGKKFQCGEEIKGKGTELFLGAAANPFAYPHEFRAVRMGKK
IANGADFIQTQIIYNLDRFAEFMKKACELGLHEKAYILAGVTPPKSVGMARYMKKFVPGM
DVTDEVIKRMQGAKDKKQEGINICVDIINQVKEIPGVAGVHVMAIEWEEAVPEICEKAGL
LPRPTFDVFGEPALAFEATGEKAAEAIEVRGADEDQDAADDILEQAKAEAEKIIAAARTQ
AAAFAGQTAQSGQATTENAAVSGQAADDAGEHAMNEKGRRAALESVNQGLNALKKAYGLS
DDQFDALMNFVDAASVLNKEPEGLTQQSVGATPAPVSAPAAPAVPAVEEKADDTAAKAEA
EAKAKAEAEAKAQAEAKAKAETAAKAEAEAQAKAETEAKAKAEAEKKAAAEAAAKAEAEK
KAAEAKAAPAAVPSDLDAPVLSTDETPFAERVTKVPASSYKAAYSGAIREVTMGNGDKAV
TVGGATSLPFHLFEGEIGNKPLIAMEIMDVRPDNWPDTLTQYFDDVMDSPVDWAKKCVDV
YKADALNIWLNGTDPNGANRPAADAAKDAAAVIAAVDVPIIVWGCGNSEKDTETLREVTS
LIGDKKVCLAPLEDANYRAIGATAMAFQHPMVAASPIDVNLAKQLNILLENLGVPLGTVM
MDPSVGALGYGIEYTYSVMERIRIAALTQKDEKLQVPIICNLGREVWKAKEVGLPTDEML
GDQESRGIMMEAITASCMLMAGGEVLIMRHPKAVNMTKA
>A0A6B2D860|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. SID8362|TrEMBL
MTSVIERLRGDGPKFSIEFFPPRDAADEAVLWKAVRELEPYDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYASVGVRNILALRGDPPGDVYGEWI
PHPDGLTYAEELVQLVRSLGEFCIGVSAYTYGHPRSPDLESDTKYLVSKLRAGADFAIAQ
LFHDAEDFLRLRDRVAATGCDVPVLPGVMPLTTMRTLQTTIKLSGAPAPRKLLDRLEPLA
DDPKAFRAAGIDVTTELCEKLIAEGVPNLHFYTFNRSKATREVIARLGLVPARA
>A0A5B0CNW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus sp. ANT_H30|TrEMBL
MGLLDELKTKILTADGGMGTLLYSYGIEYCNEELNLQRPEVIEKIHQDYIRAGADIIQTN
TYGANALKLARYGLDEQVADINKAAIEIAKRAAAPGGQFVFGTIGGIRGIRKSDATLQEI
IAMVDQQASQLLAGDPDGLLLETYYDFEELAATVKHLKGITDTPLIAQVSMHDPGILQNG
MSLNDALHQLESLGADIVGVNCRLGPHHTIQAFEEVTLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGRAALLLRQKGVRLIGGCCGTTPKHIEAVKKHLGKLPPIFYKEVTKRKPIV
IREAEALEVKPLHEKAKTQRTIIVELDTPRHLDVTKFLEGSVALHEEGVDAVTMADNSLA
SPRISNMAMGSILKHTEKIRPLAHITCRDRNLIGLQSHLMGLDALGMHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIESGADYFISQPVYTKEKIVEMYEATKHLNTPIFIGVMPLTSIRSAEFLHHEVPGI
KLSEDALERMRACGDNKDRATAEGIQIAKELIDTAAELFNGIYLITPFVRYDMTVELIRY
IRQLDQQKESDRSHVQTSY
>A0A7W0CEB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea soli|TrEMBL
MALGRPSVLPDRVPTVRELLATGRRTFSFEFFPPKDDAGERQLWRAIRQLEALRPTFVSV
TYGAGGSTRDRTVDVVERIAHETTLTPVAHFTAVNHSIRELRHLVGRFADAGVRNILAVR
GDPPGDPMGEWVQHPEGVLYAEELVRLIRQSGDFCVGVAAFPYKHPRSPSIESDVSYFVK
KCEAGADYAITQMFFDADDYLRLRDRVAAAGCDTPIIPCVMPVTAMGTIARSEQLTGAPF
PAALAARFEAIADDKAAVRSLGIDHCAEMSQRLLDEGVPGLHFITFNRSSATAEVFQRIQ
TAQALSA
>A0A8D2FUS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Theropithecus gelada|TrEMBL
MVNEARGNGSLNPCLEGSASSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDLCVAGYPKGHPEAGSLEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYE
EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDALELLNRPTQNERETEAP
>A0A1X7GL43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum oryzae|TrEMBL
MTAPISSLPSISFEFFPPKSEKMEQSLWQSIRRLAPLSPSFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGIGGRYEP
FPGGYAYAADLVEGMKRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDAYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCNASMPKKLAETFEGLDD
DPETRQLVAATVAAEQCQALQAQGVNDFHFYTLNRSDLTIAICRMLGVKAKAAPAAAAVA
G
>A0A444J1L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electrothrix marina|TrEMBL
MKSGSNLERVLRSGAFAVTGELGPPKNSDPDVVREKARILKGNVDAVNITDCQTAIVRMS
SIGAGLLAQAEGVEPVIQMTCRDRNRIGMQSDLLAASALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMVRDMRDGKKFQCGEEIKGKGTELFLGAAANPFAYPHEFRAVRMGKK
IANGADFIQTQIIYNLDRFAEFMKKACELGLHEKAYILAGVTPPKSVGMARYMKKFVPGM
DVTDEVIKRMH
>A0A0A0E045|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalispirochaeta odontotermitis|TrEMBL
MPTPFKEALDSGKFVVTSEVAPPKGTNLEKFKHHIDLLKDKVDAMNVTDHQSSVMRYPSL
GGCLLVKEQGGEVILQMTCRDRNRLALQADLMFASYMGVQNVLCLTGDSVMLGDHKQAKS
VFDLDSSQLLATVRTLEKGKDLGGNELDGKVDFCAGAIVTPEADPLEPQLIKFEKKIESG
AEFIQTQAVYDLDRFKEFMDYARQFKVKILAGIILLTSAPMARFMNKNIAGVFVPQDLID
EMASAPKGQALAKGIEIAGRMIKRIHDEKMCDGVHIMAIGKEEKVPDIMAAAGLI
>A0A0A0DZI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalispirochaeta odontotermitis|TrEMBL
MSLNTASKLEKILSEGHYAVTSECGPPRGSKPEPILEKAELIKDHVDVINITDNQTSMTR
LCSLAACIRLKLNGLEPVLQMVTRDRNRIALQSDILGAASFDINNILCLSGDHQSFGDNP
KGQNVHDIDSMQLIQMVRLMRDEAKFLGGDDLDQPVKMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNLDKFEKWMEGVRERGLHEKCYILAGLTPMKSVGMAKYMQKRVPG
MDVPDEVIKRLQGVEKGKQAAEGIKMCIESIERLKECEGVKGFHIMAIEWEEKVPEIVEA
AGLYPRPSVN
>A0A3Q8FLX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. SAU14A_NAIMI4_5|TrEMBL
MPAGTVQGARAFIDACSLEVSAKAMPALRAEAGRIAPGTTISIPYLASEDDEARLAAARI
VRELGLQPMLHLSARRIGSQAALEHFIARAVGEAGVEQCLLIAGDLATPAGPFADSAAII
ETGLLERAGIKVVAVGGHPEGHPVMDAAGRWKALERKCQAIEARGMAPKIITQFAFDADL
VLAWLDGLRARGIGHPVLVGVPGPASVTRLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPDVFVDRLVAGLTEAHGQVSPHLFPFGGIAPSLDWVAQYRRRAGSQQR
>A0A5K1I4E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas lysinitropha|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGKFAITSEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGAHCHMSSVGVCSLLTRVGYATILQMSCRDRNRIAMQGEILGAAAMGAC
NLLCLSGDGVQAGDHPQAKPVFDLDSMSLLEIARGMRDDCCFQSGRKINVPPRIFLGAAE
NPFVPPVEWRPHRLAKKASAGAQFIQTQYCFDIPRLRDFMLKVNDLGLLEGPDRVFILPG
IGPLASARSARWIREKVPGVHIPDAVIARLEGAENQKEEGKRLCMDLLHQIREIPGVSGA
HIMAYRQEHTVAEIIETTGVLEGRVPWYPGRDNPAELNPESPDARPEELEPVQG
>A0A4Q1INQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibacter sp. HS1-25|TrEMBL
MKVTEHIKNANGKTLFSFEIVPPQKGQNIQDLYNNVDPLMEFKPPFIDVTTSREEYVYIK
KENGLLEQKMTRMRPGTVGICAALKYKYDVDAIPHVLCGGFTKEETEYVLVDCHYLGLDN
IMALRGDAMKHEPYFVPTPGGNEYAVDLVDQIRELNQGKYLHNIIETTNRPDFCIGVAGY
PEKHLESPSMDADLRRLKEKVDAGADYVVTQMFFDNSKYFNFVEKARKIGITVPIIPGIK
PVAVKRHQQILPQIFRLDMPEDLISAIEGCKDNVQVRQVGIEWAIQQSKELMAHGAPVVH
FYSMGKSDNIKAIAKEIF
>A0A348HIC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymobacter palmae|TrEMBL
MSNALETSFEFFPPRTPVGQEKLASLCDRLVAYDPTFFSVTYGAGASVRERTLDAVIRAR
RGNVDAAPHLSCIGSDRENLAELLATYRREGVRRIVALRGDVPSGEISVGEFRYANELIE
FIREETGDAFELIAAAYPEMHPQAPNYETDLRYFVNKMQAGADKAITQYFYDAEAYFHFV
EKAQAQGIDKPIIPGIMPIVDADKLRRFSATCGASIPRWIDKQLDAYAMDPQSLQAFGQE
VVTRLCERLIEGGAPGLHFYTLNQAEPTLAVLDNLNVNRA
>A0A135LKY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium patulum|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKVLGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRQTHGDYFCVGVAAYPEGHPADTFQDVQDPARDMPY
LVEKTLAGADFIMTQLTYDIDAYQKFENMVRNHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIAKRMEELKHDDDAVKRAGVDIVSEIVGGMRDIPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPSFSDAGDLAIEDDPASIPLDFPGRALRRRRASSINSQPHNRVIVDKL
STHESSHASDHEARADSAGMLVPPPNRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHMTANSARRLWGHPVDDKDMSTLFRRHVSGDLHMVPWSEGGAEEDGAG
LNAETDLIRPELLKLIDGRGWWTLASQPAVNGVRNDHPIFGWGPQREGFVFQKPFVEFFC
SNNDYTNILKPIFAKHGHDKLTWFATNIKGDFESSLPTQPADMELDDLGDNPDSVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTETYLDTTKNDAWLVCVV
GQQFGAGTKRGSKEEEDEVKWMWRVLAGEDV
>A0A257QQA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidocella sp. 20-58-15|TrEMBL
MTHSPPRDALERWVTGERVMPLPGRSSTGAPAISFEFFPPKTPALETQLWACVERLATLQ
PRFVSVTYGAGGSTQERTHATVVRLVQETNLVPAAHLTCVGATREEVDDVARRYWEAGVR
HIVALRGDAPAGQTYTPHPGGYAYAADLVAGLKRVADFEITVAAYPEVHPQALSEAADMD
NLKRKLDAGATRAITQVFFENTTFLRFLDKAVAAGITAPIVPGIMPVSNFVQAAKFCTGC
GTSVPDWMADLFDGLEDDAETRRMVAAATAAEQVRFLQANGVDEFHFYTLNRPDLVYAIA
RILGVKPAAV
>A0A417ILG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. AM27-36|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTNSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>A0A126ZZI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinomonas atrocyanea|TrEMBL
MAKSAPAVNREASLQLIDNFSLEMTGKDVPGLLEAKDHIPAGTRINITFLGNEDLEMRVA
AARAVRENGFTPVPHISARRLKSQGELEEFLGRLQEVGATEHLFAVGGDPAAPEGPYEDS
LAVISSGVLQQYGVREVGIGGYPEGHPDISKETLARALEDKAAALKDQGLGAVILTQFAF
DTEPVAEWIAGVRAKGIEAPIRVGTPGPAGIKRLLGFARRFGVGANAMIVKKYGFSLTNL
LGEAGPEHFVDDLASALTDAWPHPGIPGKVGLHFYTFGGLKATADWVRTFTAERS
>A0A239CCP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura meyerae|TrEMBL
MRRVRPDRPPTVRELLAAGGRSFSFEFFPPKTDKGARNLWRTIRELESLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVDHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPDGVEYAADLVRMIRSYGDFCVGVAAFPYKHPRSPDVASDVRYFVEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDVPILPGIMPVTQLSTIERSEQLSGAPFPPEV
KARFDAVAHDPEAVRRLGVEHAAELCRELLEQDAPGIHFITFNKSTATREVYSLLGAEEY
CARGSRPPMTA
>A0A444JG65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electrothrix marina|TrEMBL
MLRTALNTPDEFTVTFELVPRQGFDRKQVDPLLDFAQQAKEDGRIKALSITDNPGGNAAL
APVAIGTELVRIGIEPLIHFSLKDKNRNQIGSHIYLYQRLRLRSLLVMGGDFPNPGYYGR
GKPVYDLDSIQVLRLLKDMENGRYPDRTGTRQKQYPAPDILKGCVVSPFKATEAEQVWQY
VKLLHKIRAGADFVVTQVGFDVRKFEELTEFLDEQGIKIPLLANVFIPTLPLARALSVGK
IPGILLSEKLAERMEAEAAAGADNARLDRAALMVSCLKKCGYRGVHLGGVNLLFQDIAYV
LDRVEQLDREGLPDNADYDFPVPGTWYYFQHRLSDNKEKKAVEPLAPGTVLGTTWMHKLG
HTLFFTDQYVTGRLFARFCLFCAKGRYRFNFLLRLEKTIKRQMYDCQMCGECTLSHSAFL
CPQWHCPKRLVNGPCGGSNQGRCEVHPDRLCFWVRVYNRLDNRTTLASLVGLPHLPPKDW
HREKTSSWVNFFSDQLNQLKEQDE
>A0A653KT83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 8I-beige|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLITGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A2N2D634|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-15|TrEMBL
MKNSIIGYPRISSQRPFIFDGAMGTYYASICENPLSPCELANLYDRNTILNIHREYINAG
CQAIKTNTFAANCISLESGIDTVKEVIQQAYNIAVEATAGTEVLIFADIGPIPVDDDTAD
LWSGYREIVDVFLTLGATNFIFETFSNDDHLLEISQYIKENQPQAYILVEFAVSPEGFTR
LGKSGRKLIENILQIPTIDACGFNCYSGPYHLLKYIKTFNTENKTISAMPNSGYPTIINN
RTFFDNTKEYFAAQMLEIARQGVAILGGCCGTTPEFIKETVAGLKGLSYGEIVSNIQIEK
THIKKTPDSNLLLEKISNGKKIIAVELDPPIDTDIDFFMDSAKSLKEQGVDAITIADCPI
AKARVDSSLMACKLKRELDITPIPHMTCRDRNINATKALLLGLNIEGINNVLVVTGDPIP
TAQRDEVKGVFSFNSAILANYISNLNETVFSSPFHICGALNVNARNINSQLQHAKKKMQN
GITMFLTQPILSKQAIDNLKKAREELDVRILGGILPIVSYKNACFINNEISGINVAEDII
ELYRDISKEEASKLAVNISTKMAEQIYPYVDGYYIIMPFKRIDIVSEIITNISSINNHQ
>A0A896TAH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYLDKTQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>A0A7C1Z4F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
MALFTPGRRWQPPFLPFKKEKFSKRLLRKIERWIKGPLFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGSTAEKCYVDETRPCIWYKIYERAYNMGREEILLEVLPPLDWDKVGTETW
GDVVRSIRKFGSRAFFKSLFTRNKEKKANAWEGVFKPVRQPEWWQGDSEYHAPAYDEPIS
ELERKLREGKFVVTAEVAPPLGTATGKLSRDIEMVRDHVAAVNFTDSASASPRMSSMACC
KVAAELNADPVLQIAARDKTRSGLQSDIIGANLMGVRNVLCITGDNARIGPTPTSNTNIL
DVDAIQMLWMLRRMRDDNIYLDGRKMKSSPRLFLGAAGSPFASEPKYQALREHKKINAGA
QFFQTNLIFDPEGLDRWLEALDARNILDKVYILAGVTPIRSKRMAHYLHDKIPGVRVPGQ
ILKRFDNASEDGYEELGIEIALDIIGSIKSKQGINGIHLMSVGWESVVPRIINEAGLN
>W6Q5U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium roqueforti (strain FM164)|TrEMBL
MHIREKLAKNEAEGKIGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEATDNGFCYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNTDVDQLIDHLKEKVDAGSSF
VVTQMFYDADNFIEWVKKCRAKGITVPIIPGIMPIQTYASFIRRSNWTKVKVPSEWMEAL
EPVKNDDSAVREIGKTLIANMCRQLVTAGIKHLHFYTMNLAQATQLVLKELDLCPSDDSP
IQRALPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISDIFVKFLTGKLDRLPWSDSPITTEAREIQEDLLN
LNQRGFLTINSQPAVNGVKSCHPVHGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKND
DLTYHATNKKGELRTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCYDAASPSRKLIHQVMDDWYLVNIVDNDFHRSNAVFELFNGLEVKDLNVELPGVPLDNG
NAEQNGVAAN
>A0A8J6TZD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aldersonia sp|TrEMBL
MDAADPVRGRASTGGVSTTPSVVSRLAPADSGRVPFSVEFSPPRDEAAEARLWRAVREFE
RLRPAFVSMTYGAGGSTRDRTVRVTGQIATETTLLPVAHLTAVEHTVDELRALVGAYADC
GVRNILALRGDPPGDPLGEWRKHPDGVEYAHELVTLVRDLGDFHVGVACFPEGHYRSPDL
DHDTEHLCKKLRAGAEYSITQMFFDVEHFLRLRDRVAACDSEQGAKPIIPELMPITSLRS
VRRMVELSGSHLPRDLERRLVQAAGDGPEENRAAVREVGIELASEMGERLIAEGAPCLHF
ITLNFARATSEVLANLGLGAAVV
>A0A7T0EQG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium versatile|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWESGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTTMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A735MZB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhisuis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8B3RCV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malaciobacter halophilus|TrEMBL
MFETLIQKLQEDKYLTLETTPQHEPIMHNIIEKVKKFDLQNRVDGFSATDNPLAKLKYNA
LFASLRLQQEFKKPVIATMSMRDRNKIALQSDLLGANEFDVRAILALTGDPAKMSDQPHS
KGVFESNSSMLLKMIKSFNYGMDIAGRPFKIEPKQIYPFAVTNSYARSFTSLEKKMHNKI
QNGAMGIITQPVFDVNNAKKLLEIFENAKEDVVGNKKKAQLIFGIFPITKLRTALFLSAQ
VPGIHVPQDWVDKLELANQISEEEEYKVGMQLSKDLFYEIKKLHPKIHLMTANKFDLADE
ILA
>A0A252A6B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter tropicalis|TrEMBL
MSLSRLSVELIPRSTEALLDDVASVKALFPAADTLNVPDLMRFPLRSWDAAALIRPHFAR
VVPHIRAIDVAPDAPLPGADQPGLEEVLVVHGDPPADLSHRTYPNSTESIIRRYKKEAPH
LRIYAAFDPYRRAPWQELEDVARKKEAGAEGFFTQPVFDLKLFDLCREWLRDETVFWGLS
PVIGPRSRSYWETTNHVVFPKDFEPTLEANIHFAQTVLRHLSQEKGRAYLMPLRVKLDQY
LPPLIEALA
>T2J8V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocosphaera watsonii WH 0401|TrEMBL
MINHFRQAVQNKEFLITAEVAPPKGGNPTRMLEMAKQLKGRVHGVNITDGSRAVLRMSSM
AASALLLQYGIEPICQMTCRDRNAIALQADLMGAYALGLRNVLALTGDPIKAGDHKRSKP
VFEVESVRLLKMIDKLNEGIDFNDKTLADEPLDLFPGAAVDPQSRSWSGLQKRFERKVAA
GAQFFQSQLITDFEKLDKFMHQIAANSDKPILAGIFLFKSAKNAQFINNNVPGVEIPESI
IKRLGEAEEPLKEGIKIAAEQVKQAQQLCQGVHLMAVKREDLIPEILDQAGIPPMVSQ
>A0A2S9JM82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium gobiense|TrEMBL
MKIIDHIKNANGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYMYKQ
HESGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDPDFVPTPGGHGYATELLQQVIDMNSGKYLHEDIESTAKTDFCIGVAGY
PEKHFESPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PMTTKRQLIMLPKIFHLDIPEELSEAVEACKTNAEVRQVGEEWLVEQCKELIKFGAPVLH
FYTMSNPGPTKKIVERLA
>A0A2E9M6I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidales bacterium|TrEMBL
MKAGTNLEKVLTXGQFAVTAEAGPPKGTSARVVQQKAEXLRPCCDAVNITDNQTAVVRMS
SLAGCVLLKQQDVEPVMQMVTRDRNRIALQSDVLGAIXLGINNILCLTGDHQGFGNHPAA
KGVFDMDSIQLIRVLKNMRDEKKFICGEDISGEVPLFIGAVENPFADPFEFRVNRLAKKI
KAGADFIQTQAVYDLXRFTKWMEMVTDRGLDKQVHILAGVLPIKAAGMARYMRDSVPGIS
VPQSITSRLGXAKNXKEEGLKITLEIIEHIRTLPGVHGIHIMAVGWEEIIPDIVSKAGLL
PRPVSGKVPE
>A0A1V4II32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium oryzae|TrEMBL
MLIKNIFKSKKTVISFEIFPPKKDNSIDTIYDTIDALKDLKPDFISVTYGAGGSTRDKTI
EIASIIKNKYYIESLAHLTCIALTEDRLKAFLNEVNRNNINNIMALRGDLPADTSENLLN
FSSYHYASDLVKYIKTNSNLGVGGACYPEGHFECKSVEDDVENLKIKVNNGADFLITQLF
FDTDRFYDFKDLAVKNGINVPVSAGIMPVTNAKQIQRMISLSGASVPSKLSRILAKYENN
PAALKEAGIAYATEQIIDLLSWGVDGIHIYTMNRPEICRKLIQNISSIRETLATAK
>E7GJH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] symbiosum WAL-14163|TrEMBL
MKIKDILAAGSPTLSFEVFPPKGEEAYESVEKAALEIAKLKPAFMSVTYGAGGGTSRYTV
GIASDIQRETGVNTLAHLTCVSSTRSEVKSVLKQLREKQIENVLALRGDIPADGPIATDY
RYASELIYDIKQFDENLCIGAACYPEGHVESVNKTADIEHLRDKVEAGCDFVTTQMFFDN
NILYNYLYRIRERGITVPVVAGIMPVTNVKQIKRICQMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAKIGDSLSEIL
>A0A059F7C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas jannaschiana VP2|TrEMBL
MANRLWDTVQRLEPMAPDFVSVTYGAGGSTRERTHETVKRIAQETSLKPAGHLTCVSATK
AEVLAVAEEYWQAGVKHIVALRGDPPAGMGAEFEVHPGGFRDAVDLVKGLREHRPELGKC
FEISVSCYPELHPESQGWEAEIAYLKAKQDAGADRAITQFFFEPETYLNFLDKARAGGVT
MPIVPGIMLQANFRGLQRISGLCGATIPDWLADLYDGLDDDEETRELVTANVAADLCRKL
AEQGVENFHFYTLNRAGLALSTCRLLGLKPHPAEAA
>A0A653V536|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 9AF|TrEMBL
MKVTQHIERAKGKTLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPSGLLQKKIVKKRPGTVGICAGIQNKYEVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKNEIYFKPEKEGNEYASDLVKQISNLNKGVYLDEDLQNSSCTNFCIGVAGY
PEKHMEAPSMDSDLHFLKQKIKNGADYIITQMFFDNQKFFDFVEKCKKAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMEVVKAKDNDAVKQIGIEWCLQQSKELIQAGIPVLH
YYSMGKAENIKAIASKIF
>A0A068D7Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium huakuii 7653R|TrEMBL
MSARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>R0JP43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium crenatum MT|TrEMBL
MSLTNIPASSQWAISDVLKRPSPGRIPFSVEFMPPRDDAAEERLYRAAEVFHDLGASFVS
VTYGAGGSTRERTSRIARRLAKQPLTTLVHLTLVNHTREEMKAILREYLELGLTNLLALR
GDPPGDPLGDWVSTDGGLNYASELIDLIKSTPEFREFDLGIASFPEGHFRAKTLEEDTKY
TLAKLRGGAEYSITQMFFDVEDYLRLRDRLVAADPIHGAKPIIPGIMLITSLRSVRRQVE
LSGAQLPSQLEESLVRAANGNEEANKDEIRKVGIEYSTNMAERLIAEGAEDLHFMTLNFT
RATQEVLYNLGMAPAWGAEHGQDAVR
>A0A0S8CJT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium SG8_51_3|TrEMBL
MNTFKEAVLDPDTFCVTWEQVAGRGAFEMQQEEIIENAMKAARRKKVHAVSVTDNPGGNP
AISTEMLCTEIRKLGIEPLVHLAFRDKNRNECESLLFGLAALGVRNILMLTGDYPSSAGF
KGQPRPVFDLDSVQGLQLVDLMNRGIDYEMAGRHVTLAPTDFFAGGCVSPFKQYESELMG
QYNKLRKKIDAGAQFIITQLGYDMRKFHEVLMWLKSTGNNVPVLANIYVLPYGAAKVMHA
NQIPGAVVTDKLLQDIDAERKAEDKGREARYLRAAKMYAVAKGMGFAGAHIGGHGLAYET
LEYIIEKGEELSARWREFVPEFEYPQKNGFYLFKKDEKTGLNAKEEAPRQEKPSRPGIVL
LSRIAHSLIFEPKSPLFKCLKPMAKLVDRSPRLKSSFTYFEHLAKVILFSCMNCGDCALF
DVGYLCPVSQCPKNQRNGPCGGSYQGWCEVYPDERLCIWVKAYRRLKAMGKEGDIEKNMV
PPCNWELWESSSWLNFYM
>A0A6N2DCM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGTELYQRGQFINNPFEGINLREPDLVRRIHREYVDAGAEVIETNTFAANRLKLRRVGLE
DEHDAINRTGVNLAREAAAGRAWVVGAIGPSGKRWVELTDRERDELCAVFVDQATVLLDA
GVDGLSLETFGTLEELRVALRSVRSLTDLPILASAAFLGNGVTADGAAPDVVARALASGG
ADLVGANCADGPMELHAIAEAMLPVGRPVAILPNAGYPKHVDGRMIYMATPEYFGVFARR
FLKLGVTAIGGCCGTSPAHIRAMSGAVRMMSGGTEPAIAPSMSVRERQDTPALTDEATAP
VPFAERSSLAGRIAGTEGFVVSVEVNPPTGLDPSRAIEGARMLQAAGVDVINIADGPRAS
VRMSNWALALEVQRAIGMEAIVHLCARDRNLLGLQSDLLAYHQLGLRNLVVITGDPPKLG
DYPHATAVFDLDSIGILRMVNQLNHGLNPVGRAIGATTAFAAACGVEPAALDYDRELRRL
EEKVEAGASWIMTQPVYDPTVLERFLDDIEDFEVPVLVGLMPLASHRNAEFLHNEVPGMQ
IPQHIRDRMERVGRGPAARAEGVRIAQEALLAVRARVRGAYIMPPFGRWEAAVEILECIG
YARPDAWRETWRD
>A0A2K9NMR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteriovorax stolpii|TrEMBL
MKVTEHLERAKNPLFSYEIVPPPRGRSVQDIIDIVEALKPVHPAWIDVTAHSSSAYYNEK
EDGTIERKIYKKRPGTIGICGIIQNRFQIDTVVHLLCLGFSKEETEDALLELNFLGIHNI
LALRGDGPNYKKEISKSRSANYYASDLVEQVKALNSGKFLDEIEGGSKFDFCVGVAGYPE
KHFEAPNLKLDLINLKRKVDAGADYVVTQMFFDNKHYFEFVKEARAAGITVPIIPGIKVL
KNTTQLVSIPKNFYIDLPDELVEAVTKDQKNVTHIGKEWATKQVQGLLEGGAPCVHFYIM
NDTNTVVDIVKKFQK
>A0A7V0JR99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLPGSLHSKLQKAMEERLAQRDSGYDVNGAKRSFVITFELVPARASKGKAIDEILQFAGE
AAAGGLISALSITDNAGGHPALTPRALGSEIMALGIDPIIHFSCKDKNRNLIESQLFVLD
RSGLKNLLVLTGDYPRYGFMGNAKPVFDLDSVQVLGMISDMNREFVLDSRAPFGGIKLAP
MSFHTGCVVSPFKRLESELIPQYLKLKRKVAAGASFVITQMGWDVRKFDELRRFMDRERL
RVPLIGTVFIPTTGLARTLCKGEIPGCILPDRLLERMEQEAISDDQEGGPRLERAARLVS
ILKGLGYEGVHLSGPGLKYSHIEWIIERAKEIGDRWKPFTCQFLFPEEWKFWYFKEDPET
WLNHDELTPESEVSLSLRDSLGLSLGRLFHELAFEPGRPLFNSLRRMAGWIDGSSSKRHF
TSFEYWLKEWLYDCRRCGDCALGEMGFLCPQSQCSKFLLNGPCGGSRDGWCEVWPGRQQC
FYVKVYERLQSLGKQESLGGPPLPPRDWALYNTSSWLNFYLGRDHHKDWVIS
>A0A7K1HFC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides merdae|TrEMBL
MKVIDLINSSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSFQKINIRKRPGSVAIASAIQNKYGITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQKTDIYHEHATDLQQQVNDFNKGIAIDGSAFEANETPFSYGMACYPE
KHEEAPNMDSDIFYLKEKVKNGADYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDDEAKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVYKVAKEVY
>A0A072NYF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schinkia azotoformans MEV2011|TrEMBL
MGFLQDLQNRILIADGAMGTLLYSYGVDFCFEELNLLQPDRITQIHETYIKAGADVIQTN
TYGANYIKLGRYGLEDQVKDINTAAVRLAKKAAKENTYVLGTFGGIRGIKKSAATIDEIK
RSFREQLYSILMEGVDGLLLETFYDFDEIKTVLEIARKETDLPIISQVSIHEVAVLQDGT
PLRIALKELEDLGADVVGLNCRLGPHHMTQALEEVPLPKKAFLSAYPNASLPDYVDGRLI
YESDAEYFGECAVNLRNQGVRLIGGCCGTTPKHIKAVSERLKGLAPVTHKDVKIKENENI
ITVTAKPTQPHLHEIVTKERSVIVELDTPKTLNTTAFIEGAKALKEVGIDALTMADNSLA
SPRISNMAMAAIVKNEVKIRPLVHITCRDRNLIGLQSHLMGLDALGIDQVLAVTGDPTKV
GDFPGATSVYDLSSFELISLIKQFNEGITFSGKPLQKKTSFSVAAAFNPNVRHLDKAVKR
LEKKIEHGADYFISQPIFNEQQFLQVYEETKHITKPIYIGIMPIVSSQNAEFLHNEVPGI
KLTDEIRRRMADCGTDREKAAIEGIAIAKSLIDMAFDLFKGIYLITPFMRYEISVELVQY
LKTKNSKNLLTRN
>A0A800LR79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MGGAKALPRKTRGDQTVQHRLLENMTYELIPLKNVRDQEAFLPANSTMSVTCSPAKTIDD
TLDLCAEFAAQGHTTIPHFAARMVESQEHVEHIVKRVNEQGIKKVFIIGGDADQRGPFYD
AASFMRAFFALSPNIDTVGIGCYPDGHQGIPDQALLDALREKQTLITEAGYHGYIATQMC
FDPNKIKSWLSEQRATGLTLPCHIGVPGAIDRTRLITISLRLGIGHSARYLKKNNSSVIR
LLSPGGYNPSKLLAQLSNHANKLNITNIHCFTFNAVDTTEDWRLKTLAKIKN
>A0A7V4PJL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTFKERLESHRFVVVAQLQPPKGIDLSEIYGHVERLKGRVDAIHVPDLQHAIMRLGSLSV
CSLLKGKGMEVIYHLSCSDRNRLALQSDLLNAAALGLQNILVRQGDHPSIGDHFEAKPVF
DLDVMGLLAAVKRLQEGYDLGGNDLQGKPQFYVGTEVNATAKGHALDLEVMDMEKKIRLG
VEFFFTNSIYDPRLLENFIKKVAHFKVPIIVGITLLKSVGMARYMNKHVEGTYIPDSLID
RLMKASDKQKESIEIASELIREMKPLVQGIQIIPLGWENLIPPLLDQVGL
>A0A6I1QW59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLADLYAQPGLTLSVEFFPPKTDKGEESLFSEIELIKSLRPAFCSVTYGAGGSTREKTV
ALVDRIHQDRGLEVMCHLTVVSQSKDEARNVLKTLQEKGLENVLALGGDPPQGMMDWKPH
PDGFRHAVELVREAVSFGCFSIAVAGFPEVHPRAESRTSDLRYLKDKIDAGAKAIITQLF
FDNEQYYRYVEDVRKLGVEVPIIPGVLPILSAPQIRRFTSLCCSRIPAQLEQALVKVEND
DDAATELGIEYATRQCEALIKFGVPGLHFYSLNKSYSVIAICQNLGI
>A0A7C3NXX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLCGRYPAFSLVAAPSADDAQQGLARVKLADLYAQSGLTLSVEFFPPKTDKGEESLFQEI
ETIKNLKPAFCSVTYGAGGSTREKTVELVERIHRECGLEVMCHLTVVGQSKEEARSILRK
LKEKGIENLLALGGDPPQGMSDWKPHPDGYHHAVELVREAVALGGFSIAVAGFPEVHPRA
ESRESDLRHLKEKVEAGAAAVITQLFFDNEDYYRFVEDVRKLGVTVPIVPGVLPILSVPQ
VRRFTALCRAKIPANLERKLAAVENDDETAVALGIEYATRQCEELMRFGVPGLHFYSLNK
ARSLKAICKNLGLH
>Q0SY49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella flexneri serotype 5b (strain 8401)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7C4SG15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MVAFKERLASGAFSFVVELQPPKGIDLSDFLEQAKGLKNHVEAVHVPDLPNGVMTLGSIA
TCAKLKEAGVETIFELSCGHRNRLVLQSDLLGASLLGLENVLLRQGESPAIGDHYEAKPV
FDLDGIGLLEVAKGLEEGHDLMGNALKGKPRFFVGSPIQIRSEPKDFDLELREMERKIGL
GAKFFVTTVIYDPRLFEAFVKRAASLHVPVLASLPLLKSAGMARYMNKHVEGAVIPEAVI
ERLMKAPDKQKASVEIARETIRELRALCQGIRLIPMGWESLIPLVLDRGGL
>A0A661TDR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNLKTPSKLEKIMAAGHMAVTSEVGPPRGSDPEAIITKAGLIRDHVDAINITDNQTSVTR
MCSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAASFDIYNMLCLSGDHQMFGDCA
QGQNVHDLDSIQLLQTLRRMRDEGKFLGGADIKRPPRIFAGAAANPFADPFEIRVPRLAK
KIAAGAEFIQTQCIYNLDKFEEWMRLARERGLTEKVYIMAGMTPMKSAGMACYMKNRVPG
MDVPDEVVKRMADTPKEKQAEEGIKICIEAIQRLKEVEGISGFHIMAIEWEEKVPEIVES
AGLYPRPDVN
>A0A661T0N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKRMSHLKQVLEQGNFAVTAECGPPKGADAETVLKKAAFLKDKVDAINVTDNQTAIVRMS
SLAACSLLKAHGYDPVLQMVVRDRNRIALQSDILGAAALGIGSVLCLSGDHQVFGNQPGA
VGVFDLDSIQFVQVVKTMRDEGTILDGDPLDTRPDMFVGAAANPFGDPLDFRAVRLAKKI
AAGADFIQTQCIYNLDRFGKWLQMARDRGLTEKTFILGGVTPLKSAGMAKYMKNKVSGMD
IPDEVIKRMAGVPKDKQREEGLRICVETIQALREMEGVKGVHVMAIEWEEAVGDIVERAG
LLPRPAVL
>A0A509LJH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSDLNTASNLEKVLKAGHIGVTSECGPPRGSDAEEVKKKGMLIKDHVDAINVTDNQTAMT
RMSSLAACVHLKLMGIEPVLQMVTRDRNRVALQSDILGAASFDIPNMLCLSGDHQSFGDC
AQGQNVHDLDSMQLIQTVRHMRDEGKFLGGDDIKRPPKIFVGAAANPFADPFEIRVPRLA
KKIACGAEFIQTQCIYNIDKFKEWIRRSVDRGLTEKTFIMAGMTPMKSVGMAKYMKNRVP
GMDVPDEIIARLAGAEKGKQAQEGIDICVEHIQELKEIKGVSGF
>A0A4R8UY68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. HLT2-23|TrEMBL
MSACNARPAFSFEVYPPKSVAAASALTRTIDHLAAAGPEFISVTYGANGSSRNSSLDVLR
YIKDHTTVDAMAHLTCVGSSHAEASRLIREFLDAGIRSFLAIRGDAPQGAVEGDTAFLGD
LHSAGELVQLIHRVQTERVPYIETVIPGLPAARGLKTERSRVRIGVAAFPNGHPNSRSVA
QDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLFPILPGIMPVTSPNRLRRI
LQLSGEKLPAELSIELEVEPTEEGQRQIGIDYAVRLGQDVLAGGAPGLHLYAFNQHETVL
SVLEGCGALPVPAAMP
>A0A534ZK50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKISQLYARGRPVISFEFFPPATAAGEEALMRTVDALRPLGPGFITVTRTGTKPREAPVE
LVTRIRALGLEGAAHVTCIEASRDEIATHCVLIARRGIENVVTIRGDRPKDPGFRPPANG
FRYALDMIRFIRERGHDFCLIGGGHPEGHPECRDRERNIEHLKMKVDAGLDVVITQLFYD
NTDYFGFVERARRAGIAVPLVPGIMPITNWPQIERITALSGNQVPLRLRAALERVREDEP
AAVAVGVEWATRQCAELLRGGAPGIHFYTLNRSPATRAIFENLRREGVIAR
>A0A496Y9Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRKTKTPSRLEKVLAAGHLAVTSECGPPRGSDPAVIIKKAEMIKDHVDAINVTDNQTAMT
RLCSLASVIHLKAMGLEPVLQMVVRDRNRIALQSDILGAASFDINNILCLSGDHQKFGDC
PDAQNVYDIDSMQLIRMARHMRDEGKFVGGDDINRPPRMFVGAAANPFADPFEIRVPRLA
KKIEAGAEFIQTQCIYNLDKFELWLKQARERGLHEKAFILAGITPMKSAGMARYMKNRVP
GMDVPDKLIKRMSSVPPKKQPEEGIHICVETIERLKEVEGVSGFHIMAIEWEERVPEIVE
RSGLYPRPKTG
>A0A661QZG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSKLKEKLESGEFVVTVGLYPPRGADTGEFLAILSKLAGKVDAINLPDSRGASIRLSALS
ASILAKEKGLEPILTVSCRDRNRIAISADLLGAHALGIDTVLCVSGDYVSLGDVPQAKPV
YDLDSVQLINMIRQMEAGQDIGGNELKGIPKFFVGCVANPIADPIEPHLLKLQKKLTAGV
DFIQTLDLYSLEATAEFLNFLEDKGVKALAGLRLVTIADIEQYERGRIVGNEIPSEVISE
IKSASTDVEALARAQEFLVAMIKDIRAENRWSGIHLTMNGHDELIPQILEQAGLGK
>A0A3D5WES7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLREALAKRKFLVTTEIQAPIDEEPEGIVKTFNLVRGRVDGVSVSEVEIEGIVGDTIKT
CEVLKQNRFEAIYQTSTRQKNRLQLQKDLILAHEAGVENLLVFTEDYRITGDSLQEIMFF
HVDSGKLASVLEHIREGRTVDGKELPYKAEFILGSGVESCWGKNVPELEMKEMEEMTRIG
TGYFLTTPVFDLDRFEKFVKTVGTFGVPVIAEVMILRTAGMGRFLNRHFKSGLVPEWIIQ
KLAKASDKQKASIYLFADIVTGIKDICQGIHIITIGGEEKLRYYLDAAKLR
>A0A4P8EW74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MNFFSEYHQDIMNQKLENIRNSIHCSFEFFPPKNSALEENLWSSVKRLSKLKPKFFSVTY
GANSGEREKTYDIVNKIYKKTGIITAAHLTCIDSTPAELKKIAENYWNNGIKSIVALRGD
TSKKDYKHKMYALDLVVLLKKIANFDISVAAYPELHPESKSSKLDILNLKKKIDAGANRA
ITQFFFNIESYLRFRENCIKNRINVEIIPGILPICNFKQLQRFSKMTNIKIPQWMFEMFN
GLDNDLVTQKIIGSSIAIDMVKKLSFEGVKNFHFYTLNQSDITYAICHILGL
>A0A661I013|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MIEQLIEKLHNGTYITLETTPTHSPKFLPIIEKIAALELDKKVDGFSTTDNPLAKLKYNA
LFAAKMLQDRFNKPVIATMSMRDRNRIALQSDMLGANEVNIRTILALTGDPAKISDQPHT
KGVFESDSTLLLDMISCFNSGIDFAGKPLLEKPETIYPFAVVNSYAKNPKTLQKKMQKKI
FHGVQGIITQPVYDIENAKVLLDLMENANKENSKRNDAQLILGLFPITKMRTAQFLASHV
PGINVPSLWIEQLRKANEISPEEEYKVGFELSKKLFDDIKALHPKIHLMTANQFGIAKDI
LS
>A0A2D5SRY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEPADDLQENIEQXTTWSMEILPHNIAEVSLIPEFINEIYITMIPGATCLETIEAAQKIQ
AVGKQAVPHIAARSFTGAEDLEXCLSGLEAAGIXRALLIGGGHSXXAGKISCVMDMLKTG
LFAKYGINAFDFAGHPEGNPDDPNSAVHMLEKLRWAEEQGASARIVTQWSLDTECTNAWI
SGLREKGVNNPIHLGIPGPSTXKTLMRFAKXCGVKASTTVLRKQGLNLSKLMFVNKPDKI
IEELRGYDQLHLFPFGGIERSSAWLTEWQTKSYI
>A0A661NH96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
METKSGGNLEAVLRAGHFAITGELGPPRGANVEAVHKKAAYLKDKVDAVNITDNQTAVVR
MSSWATSLLVIQDGLEPNYQMVCRDRNRLAMQADILGAYAHGIRNMLCLSGDHQKFGDHP
HSKGVFDIDSIQLIAMVRRMRDEGKFLSGEDIDTPPRIFIGAAANPFAEPFEWRITRLAK
KVAAGADFIQTQCIYNMEKFRRWIHLANEEGLTEKVFILAGVTPFKSLGMAKYMKNSVPG
MDVPDHLIKRLQGAKGKKGAIAAEGIKIACEQIQEFREMKGVAGVHLMAIEWEHKVPQIV
EQAGLLPRPRVDGGNGGAPAAGE
>A0A661TBB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLKEKIEGGKFAVLAEIEPPKGSDTTNMVKNAMRVKGEVDAFIVPEMSNAVMRMSALGG
AMILEERGMETVMQICCRDRNRLALQGDILAAGGCGIMNIMVVSGGDTGSGDHHQARAVY
DIGQTELLQAIQTLQAGRDMAGIELEGAPGFMVGSVVNAGATGRELDREMVEMDAGIKAG
CEFFIIPPVFDTGAVKPFLDRAKERRTRIIPTVLLLKSLGMARYIARNMDNIHIPDEIIR
RIQKAPDKARECVRLASEMVATVKKAGFPGVNLVTIGWEKKIPEILGGMGV
>A0A661JI64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
NNILCLTGDHQRAGDHPQAKNVFDLDSVQLIAAVKAMRDEGRFLNGEELTVPPKLFIGAA
ANPFADPFEIRVLRLAKKVAAGADFIQTQCIYNLERFREWMKQVVDMGLHEKVFILAGVT
PLKSVGMARYMKNMVPGMDVPDELIARLKGVPKEKQPEEGVKIAIETVQQLKEIEGVSGV
HIMAIEWEEKVREIAEGAGLLPRPEV
>A0A535BIP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLADLYARPGLTLSVEFFPPKTDKGEENLFNEIEIIKRLNPAFCSVTYGAGGSTREKTV
DLVDRIHRECCLEVMCHLTVVGQSKDEARSILKKLKHKGIENLIALGGDPPQGMADWRPH
PDGFHHAVELVREAVALGGFSVAVAGFPEVHPRAVSRAADLKYMRDKIDAGAVAIITQLF
FDNDDYYRYVEDVRKLGITVPIVPGVLPILSAPQVRRFTALCCAKIPAPLERELAKVEND
DDAAVKLGIEYASRQCEALIKFGAPGIHFYSLNKSLSLRAICKNLCL
>A0A3C1EH81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
DPPKLGEYPDVTGVFDVDSIGLVQVAANLNRGLDIGGNPIEPPTGLFIGVGANPCAVDME
REIDRYFRKIDAGAEFAITQPVFDPEALLRFLDRVGTYRRKIPVLAGVWPLLSFKNAEFM
NNEVPGVVVPKPILDRMARCKTREDGRKAGIEIARGIVERISDRVDGFQVSAPLGHVETA
LAVLAKSF
>Q0U6C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)|TrEMBL
MHISQKLAQAKAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQTVYGLETCMHLTCTDMEKTKLDEALRDAYQSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVKYIKEKYGNHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGATF
IVTQMFYDTDIFIDWVNKVRAKGVDAVIIPGIMPIHTHASFLRRAQWTRCNIPQHWTDAL
EPIKNDDVEVREVGKGLVADMCRRLIEAGITHLHFYTMNLAQATRMVLEELDLLPDPGSP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPLSIKDLSDLFVRYMEGKLESLPWSEQPITGEATSIRNDLID
LNRRGFLTINSQPAVNGAKSSDPTFGWGPRNGYVYQKAYLEVLVSPEYIAEIITRIERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHGGASPSRFVIQDVVDTWYLLNIVHNDFHATRGIFPIFDGLQVKDIDKKLHSVNIDL
PGAEETNGANGTNGANGKNSETKEAYGEEKQNPGLLAVAKAAAIEVTNGIKGLGVSN
>A0A661IYQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGLREAFASGKFVVTAEVGPLKGTDTTEIKEVAHLLKGKVDGTNVTDQQSAVMRLGSMVT
CYLLKQEGLDPILQVTCRDRNRLAIQSDLLSAYVLGIRNVLAITGDFPSLGDHPDAKAVY
DLDSVQLVWTINRMNQGYDIAGNELQGKTDFFIGAVVTPITDTEAAMELQLIKMEKKIEA
GARFFQTQAVYDVDAFAKFMKRAEKFGVPVLAGIIPLKSVGMARYMNKNVAGVFVPDHLI
EEMQKAEKPAQKGLEIAARLIRDVKDLCQGVHIMAIGWERKVPEILELAGLA
>A0A3M1KPU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MFISKLFEAGRAPVFSLEFFPPKNEDGWRSLRETVARLADLQPGFVSVTYGAGGSTREQT
LELVAEIKKTTGIETMAHLTCVGATREELDRILDRLEASGVKNVIALRGDPPAGGSTFVA
TAGGFEHAIDLVRLIRSRRRNLCVAVAGYP
>X0QTR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. JCM 18900|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALSA
RGTTEIAPHLSCIGDDKSEIAELLEYYKTLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
YIREHSGDHFHIEVAAYPEMHPQARSFEFDIDNLVNKYQAGANASITQFFYNADSYLYLR
DKLEKRGIDTVAQPLVAGIMPITNSSNLLRFADSCGADIPRYVRKQLTDFGDDRKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKIEPNKRLVEALGLTA
>A0A661LPA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSNLERLLERGEFVVTGELGPPKGPDANVVKEKAAMLKDHVDAVNITDNQSATVRMS
SIAACKILIDEGLEPTMQMVARDRNRIAMMADLFGATALGIKNMLCLSGDHQIFGNHPEA
KNVFDIDSIQMIHMVKTMRDEHKVICEDEIEGEFTMYIGAACNPFADPAWYRPHRLAKKV
EAGVDFIQTQCIYDMNRFRAFMKQVVDMGLHEKCKILAGVTPLKSIGMARYMAANVSGII
IPDDMINRLRDAGKGNVAAEGIKILCEQMQELKDIEGVAGIHLMAIEWEHRVPEIMKMAG
FLPRPTV
>G4MZ63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)|TrEMBL
MDKITDKIAALPPDASYFSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
AQKSLELAEICQRELALTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRPGE
YAIPDDSEGDVNEFTWAIDLVRYIKLNHGDYFCVGVAAYPEGHAEESHPTNQSLEHDLPY
LVEKTQAGADFIITQLFFDISAYEKFEKTLREHPSGAFKDIPIIPGLMPIQNYQMIKRTT
KLSHAKIPDPLMARLDAVKKDDEQVKKVGVDIISELVDQVKEVKNRSSGPKGFHFYTLNL
EKAVSFIVERTNLIPATTPDDDEVAVVDDVALPSIHLNGATPAKDHLSVSSLHPPTHTNS
RRPSTIGSDPRNRVIVSSGRPASHPDYEATGFEASVPAQAINSRANTLAISEGEGVLGRE
ATWDDYPNGRWGDARSPAYGEIDGYGVSLHMSGTQAVQLWGRPATVEDVSNIFMRHLRGA
LPAIPWSEEEFNAETETIRDTLLALNSRGWWTVASQPAVNGLRSNDRTFGWGPQNGFVFQ
KAFVEMFLPSKDWKALREKLLSEKDVVCFYASNAKGDFESSDGGGDAPDGAPTGNGFADE
QPLPSGSSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWAEWAKVYGKDSPSEKL
LESLRADLWLVNIIHHDYIEKEALWDLLLK
>A0A424LRF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED243|TrEMBL
MSHANDTATRPSLSFEFFPPKDDAGIDRLMSGTASRLSAFDPEYFSVTSGAGGSTREGTQ
ALVEKLVRSGANAVPHLSVGGSTDAEVGRLVEHYRNLGIQRILCLRGDQPSDGNQHAVFA
RDLVEQLHQRFPGQFELSVAAYPEIHPDSASAEEDMRYFAAKVHAGASSAITQYFYSPDA
YEYFMERCEKAGVHIPVHVGVMPITNIDSLQRFSAKAGADIPRWLSKSMAGYADDEKGLV
SFGVEVVTNLCEKLLTMGAPGLHFYTLNRWGASSQICRNLGFPEH
>A0A8I0Y7R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAPGSQRTETFIDAFSLEVSAKAMPALRAEADRIAPGTTISIPYLASEDDDARLAAACT
VRELGFEPMPHLSARRIGSRAALARFLERATSEAGVEKCLLIAGDLSAPAGPFADSTSII
ETGLLERYGIKVVAIGGHPEGHPVMTAEDRWHVLERKCQAIEARGMAPLIITQFAFDADI
VLAWLDALRARGITVPVLVGVPGPASIARLARYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFMDRLLSGLTDAHGPVSPHFFPFGGIAPSLGWIERYRRRTSTANV
>A0A366I8N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalibaculum bacchi|TrEMBL
MSVERVPFKDAVLDKDKFSVTWELVPGRGSHEKDQDAVALCAKAAVKDPRINAITLTDNP
SGTPAIHPAGLSKEVEDLGIDALIHFTCKDKNRNEIESELYALDRVGLKNLLVMTGDYVT
AGYNGRPKPVFDVDSVQAVRMIEKLNAGLEVPMRGKLKKFPETDFFAGAVVSPFKSLEAE
TMAQYAKLHQKVAAGAKYIITQVGWDARKFDELRKYVDKFELNVPIIGNIYILTLGVAKM
MNRGVIPGAVVTDEFLKDLEAEKKEFENNKERQLLRAAKLFAVLKGIGYDGVTIAGHGIK
YEDIKFILDKGEEFAPNWQALVKEFDYPEQNGFYFFEKDEKTGLNTTTPVDRSKTGEKST
SLFYWSFSMVHKLALSEQAPLYPMIKWFAKKIDKSALKKPFTYAEYYTKTLTNECKFCGD
CVMHELAFQCPMSQCAKHQRNGACGGGKDGWCEVYPGEKRCIYVNMYEKLKHDGKEYIMN
NRYAPPADWNLYQTSSWLNFFNERDYNHRNDD
>A0A7T3DZB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILTLRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQILDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1F5V5Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Fischerbacteria bacterium RBG_13_37_8|TrEMBL
MGTQLIVRGVPVHYCKEEQNLLNPSLVLSIHEDYIRAGAQIIETNTFAANHVQLRKYNLE
KKVKKINQEGVRLAKDAARRSDVYVAGSVGPLGALIKPYGPLSLQEVSQTYQEQISYLIE
AGVDIIIIETISSLIEAREAVKAAKSIASIPVICQLTIMADVKTKFGDDAEASLRTVAFD
GADVVGINCSLGPRETYDVLQALINKLPYYISVQPNAGYPAIEKGKPVYYSSPDYLKRYA
KLYAELGANIVGACCGSGPEHIQTMAEVILKKKPKRTITSPVSILEPEKKETAPLEIEYK
ACSLKEYMKKDFILTVEIDPPKGWDYAKLLDESMRFKRQGLDLVNIADNPMARVRMSSIV
MSYLVKERIGLEPILHFTCRDRNILGIQSELLGAAALGINVILALRGDPATIGDFPKATS
VFDVDSLGLVKIINSLNKGYNFSGAPIDSRTNFIIGIAGNPSSKNVDGDIERIAEKVTEG
ARFIQTQPVYDIEKLIAFKQKTDYLN
>A0A2T6G8F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus elgii|TrEMBL
MKPDLREALRRQVLVGDGAMGTYLYQMGFPVGISYEELNLLEPDVIMDVHRRYYEAGARL
IETNTFSANREKLSKYGLEQEMEAINRAGVELAKKAVGDDAYVIGAIGSIRAGKRKNVRT
AKVKEDFRDQIEVLVDTPVDGLLLESFYDLEEVLIALRLIRKVSELPVICQFATEGTGST
HDGILLTEAFRKLTAAGADVVGFNCRSGPNGLMRSLQRVAGMEGAPPFSVFPNAGIADYV
DGRYTYAATPEYFGETARKFVDLGARIVGGCCGTTPEHIAAMVQSLQNYAPDPGALRLLQ
EAGEGSGAGRIVTRLQPVPSPPAPEPNLAELAKERYTVIVELDPPRDLDIEKFMQGAQAL
KNAGVDALTMADNSLAVTRMSNLALGSLVKERVGMKPLIHIACRDRNMIGTQSHMMGLHA
LGIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKSLKKKANFVVG
AAFNPNVKHLDKAVQRLERKIESGADYIMTQPVYNAELIEKVYEATKHLDIPIFIGIMPL
ASGGNAEYLHNEVPGIQLSDEVRQRMNGLKGEEGRAMGVQIAKELLDAAMHYFKGIYLMT
PFLAYEMTVQLTEYVWEKAHRLDSHLYPLSK
>A0A7W9NFN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kutzneria kofuensis|TrEMBL
MTSRPFKVVCEIEPPTRPDLMHVRHQIGTLSKVADTFLIPDNHIGRATVSSVAVAHEVQA
MGGRSIACLNSRDRNMLGFRRDLLTAAAYGVEEFLFVYGDKPASGSRTGQLTVRSMIDEV
RSLSEDKAFAGVAPFRVGTAAGLRPVPAWKHAADFMFVQVSFSLDALLRWRDANPVDMPV
YAGVMVIASAAHANRLAAAIPDIDIPADLVDRLDGDRLAGVESTCEQVLRIRESGAFDGV
HLVPVARYREVAARLEQMLK
>A0A651HUJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MTGRRFVAEGPGDLRARLGDGRIHLLDGAMGTVLYERGVFVNVCYDELNLSRPELVEGIH
REYVEAGARILETNTFGANPVKLSSFGLEARTVEINRAAVERAREGAATARLPAGESCSD
VLVLGALGPLGIRIEPWGPTAEEEARGYFTRQVEGLLDGGVDGFVLETFQDVRELGQALR
AVKEMCDLPVMTQVTVEGGGRTSYGTDVEEAVRLLEEWGADAVGVNCSVGPAEILDALER
MTAVSAVPLSALPNAGLPRTVGDRKIYMASPEYMARYARRMAEVGARFIGGCCGTTPDHI
RAMGEALEGLEQAPVRRAPPSPVRIRTGSPRPPEPLGERSPLGRRLAEGQFTTSVELVPP
LGWDPGALLGEARRARLAGVDLVSIPDAPRARARMAALPAAMLVQRETGLDVLAHYACRD
RNMLGMISDLLGAAAAGVRNLLAVTGDLPPTGPYGDRASTLDIDSIGLTNVLHHLNRGVD
PGGSPVEVPTPFVIGVALNHGATDLEREHRRFRWKVEAGAEFAVTQPVFAPDALLRFLDQ
AFAGDGPEIPVLAGVWPLDSLRTAEFLHHEVPGIQVPEEVMERMREAEARGGDAAGEEGI
ELAVTAATALFPRIRGIHVAAPRGSVERALEVVRRVRARMAAPVGVDG
>A0A2J0TBQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRTQLDRAAAKLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIAFI
RAEHGDAFRIEVGAYPETHPQAQDALLDLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VQRLGVQVPITPGIMPISNFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGAEVV
AKLCQRLIDGGAPGLHFYTLNLAKPTVSVLTLLRG
>A0A1A6XWA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAATRLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFRIEVGAYPETHPQAADALSDLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPISNFSQLRRFSEQCGAEIPRWIGRKMLAYGDDAASVRAFGAEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTLSVLKLLQG
>A0A0M0NJ71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAGLSLRADAFINAFSLEVSAKAMPALRAEADRIPRGTVISIPYLASEDDDARLAAART
VRALGFEPMPHLSARRIGSAAALARFLERAVGEAGVARCLLIAGDLATPAGPFADSASII
QTGVLEQSGIKVVGIGGHPEGHPVMSSDERWQALERKCQAIEARGMAPWVVTQFAFDADT
VLAWLDALRARGITIPVLVGVPGPASIPRLLRYATMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVKGLTSAHGQVSPHFFPFGGVAPSLEWMAQYRRRTSSKGG
>A0A0C9URE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerobolus stellatus (strain SS14)|TrEMBL
MKLKQKLENRSRPFYTFEFFPPKTDQGFSNLLGRIERMAVFNPLAISVTWGASGSTKDRS
LELAGLTQAEYGIETILHLTCTNTEGGMIDEALKGAKAHGIQNILALRGDPPRGAEYWIP
TDPRFVHAKDLVAYIRSEPEYAEQFCVGVAGYPDGHPDHDVDEETELENLKAKVDAGADY
IVTQLFYDVDGFLDWVKKVRAKGIQVPIIPGIMPIQSYASFLRVTKLCGTRIPSEIIAAL
DPIKHDDQKIKDYGIKLCINMIRRLYQEGHIQGYHFCTLNLEKSVRKVLEGLQWIGDGQK
PAENKLIAESEEEREQAVNGESTLIITPHDATVSAMSSLAGKAPSEAGSVGRGELNHAAT
WDEFPNGRFGDFKSPAYGLQDLWDASSGLGVKPEQARAQWGYPKSVEDLTNFFLSYLHSK
DGTTPFSSGPLFAETQMIIPHLEKLTKRGWWTVGSQPTVDAAPSEDEVVGWGPRGGYVFQ
KAFVEFFADPEDLQWLKNVVNKRGGGKVSFLAANVEGEYESNLEDDATNAVTWGIFPGQE
VAQPTIIERENFLAWKDEAFGIWGAWAQIYPPDSAERKVLDHVRKTRWLVSVIHHDYKDT
DALWTFLLQD
>A0A2T1IC40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIEFI
RAEHCDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLLEGGAPGLHFYTLNLARPTTSVLKLLHG
>F0WFI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Albugo laibachii Nc14|TrEMBL
MSKIITSIQSTYQQHFDLTHASTAHPRPTISFEYFPAKTEDGIFNLLNRIEEMGFTLQPT
FVTLTWRSAFKDASLWLRIGAHVQKCFELNVLMHLTCHLSRDCIREILLQARAMGICNIL
ALRGDPPMGKDRWVPNPEGFNNAVDLIRFIRQEHGDYFCIACAGYPEVHTESWNQPEYLP
PSQEAKSLDLERLKMKQDAGADFIITQFFFDVDNLLCWIQQCRLAGITIPILPGYLPIQN
YNSFVKFTQWCKTRVPGTILETLKTLRNDDVAVKEYGTRLAIETCEKILKAGIPSLHFYT
MNLATTVTKILCGLDLIPSPSERELPWHTTILRRNGTEINHRKSSGELDDKAMRQSVNGH
RESNGHPRKSKDERVRPIFWSNRQASYIARTSGWDDFPNGRWGDRTSPAYGEISEYYLAF
KRPKVNRLEMWGKPSSESNVWNVFVRYLSGQVSQLPWCEQALSKESLVIREKLKWINQHG
FLTINSQPRVNGASSKDSNVGWGGADGFVFQKAYVEFFCSPLWTEKLLKAMEKYPTLSYH
ALDRQGKEYRNKPADSVTAVTWGVFPGREVLQPTIVDTSSFQAWKDEAFELWQTQWATLY
EKDSETFRVIQAICSSYFLVNIVDHDYTNENSDIFRIFTRLIADEMSEEALHDRMFELEH
TNERLHENVTQLIHLQDALMGDLKQAHSEMESLRRENNTLALRVRELESQLASPQLRWKN
T
>A0A345QNQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. SK012|TrEMBL
MRSTCCQVSHSTRCESSPPFAGHFSSSINASSGSNHQENFALDKEQSTTHPPLVDQPPAA
LLKRLFQSGGKVPLSFEFFPPQTASRRDHLYEVTDRLAPVAAEGFSVTMGAGGATRTGTH
ETAVAITERCARPVTAHLTTLGMSKTEALSCADGLWSSGVDRILALRGDQPKDMTETPSG
FEHACDLVKALSRQHPFEIAVAAYPEKHPDAADLDTDIDHLKEKIDAGASRAYCQFVLDP
AAYGRFLEKCDRHGIHAPIVPGLMPLDDWKRMRSFAVANGTSVPAWLDQLFTIGETTPEI
MPNLALAAMVEQARRLIAYGAPALHVYTMNRWPLSLTLARLLGH
>A0A4Q2FQ18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLQTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A7W6PQJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium rhizoryzae|TrEMBL
MTHPVRPAHDFRLSYEFFPPKSPEMEEQLWQTVDQLALFEPEFVSVTYGAGGTTKRPTFA
TVERLISKTNLPTASHLTCVDADRDETHDVINELRAMGVKHIVALRGDPSSGVGTAYVPH
PHGYENAAALVAALKAEGGFEISVSAYPEKHPESRDVNADIEMLKRKADAGADRALTQFF
FDNDVFERYMEQVRKAGILIPVVPGIMPIQNLTQLKRFASRCGAGIPAFLDARFEGLDDK
PEERAKVAAEVAAEQIQDLMRRGLDEFHLYTMNRAPLVSAVLTNLGRLPKEKAQTGAAA
>A0A839I189|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliivibrio sp. SR45-2|TrEMBL
MAYSHASHLESLNQNIAELNGCINVSFEFFPPSSEKMEETLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLIAAPHLTCIDASRSELIDIANDYWANGIKDIVALRGD
IPAGGGAPDMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQASRFAKMNNVRIPGWMAQQFE
GLDDDPVTRQMVGASHAIDMTRILSREGVKDFHFYTLNRAEHTYALCHTLGVRPDVNR
>A0A8J7NRY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atractosteus spatula|TrEMBL
MVNELPQTDSSGQPWRCDSSGASSSGGDSSKESSRCSTPILDTDRADRLRDKMRRRMDSG
DCWFSLEFFPPRTSNGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTA
VNYCGLETVLHLTCCNQTKQQITAHLSKAKHLGLKNIMALRGDPMGDEWEEEEGGFNYAT
DLVKHIRSEFGDYFDICVAGYPTGHPEAVTYEDDLKHLKEKVDVGADFIITQLFFRPETF
LKFVKDCRAMGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIKRVIEPIKDNDAAIRN
YGIDQAVGMCKVLLKSGVVPGLHFYTLNREVATMEVLKQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKCSKEA
LLKMWGEELMNEESVFEVFTNYITAKPNCAGNKVMCLPWNEDPLAPETNLLKDQLEKVNH
RGVLTINSQPNINGSPSSDPVVGWGPPGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRV
NYHIVNVKGKNITNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWA
KLYEEESPSRMIIQYIHDNYXNNSILATAGLPTASPLHSLNATLENLHSCIQ
>A0A1Q6PKI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. 41_20|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNQYNVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>A0A1E4T374|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] arabinofermentans NRRL YB-2248|TrEMBL
MKITDKLLEAHKEVSSPATFSFEFFTPKTTQGVQNLYDRMDRMYDLNPLFIDITWNAGGK
LSTLTSEMVHTTSTVLGLETCMHLTCTNMKLEVIDQALKSAYESGCQNILALRGDPPLDG
SDSTGDFKYAKDLIKHIRKQYGDHFNIGIAAYPEGQPEESDRKKTLQYLKEKQDAGGDFI
VTQMFYDVEHFINWAHECRELGITIPIVPGIMPISTYAAFLRRAGWSEINIPQHFHDRLS
PIKEDDAKVREEGTKLLIEMCQQLLDSQVVNHLHFYTMNLEKSTLMILQGLNLITKQQIN
DMKKQPWRKSLNPTRSSESVRPIFWKNRKFSYIQRTSNWDEFPNGRWGDSRSPAFGSIEL
CDSELIRHSPKKAIELWGKPTSLKQLADLTIQYLEGEMTCLPWSDGRISQEITSTKPQLI
ELNSANIVTINSQPSIDGLKSNDIIYGWGPKDGYIYQKQYLEFVIPSTKLDELISRIDKL
NATQGSSDYNILSYYAANIGSDSTLVTNTQSSDINAVTWGCFPGKEVVQPTIVEKISFLA
WKDEFFSILKKWQAIFRSEIKLQSDDEESKSAIEFLETLHDDFSLVNIVDNDYVNEPNTR
IFELLKGL
>A0A2N0WWK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychromonas sp. psych-6C06|TrEMBL
MTNETTQQSYFSAQYLAKLNQNIADIKTEVGVSFEFFPPATPAMEETLWGSIERLKTLKP
KFVSVTYGANSGTRDRTHDIIKDIKAKTGMVAAPHLTCIDASKEELRQIARDYWQNDIRS
IVALRGDIPEGETKPHMYSTDLVKLLKEEGDFDISVAAYPEKHPEASSAQFDLDVLKAKF
DAGANRAISQFFFDAETFLRFRDKCVKQGIDGDIVPGILPVSNYKTLVKFAGLTNVHVPD
WMHKLYQGTDNDAMTRNLIGATVAMDMVRVLSQEGVKDFHFYTLNRSDLSYAICHSLGLR
PE
>I4ZWJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. HA|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADNFDADIKRFCEKAHAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A357VE82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MTESRLERLLSQGHFVVSGEIGPPKHTSPEGILHHAELLKDYVDAANLTDNQTAIVRMSS
LAAAVHVLRAGVEPIMQMTVRDRNRIALQSDLLGAYSLGIRNVLCLTGDHQSFGNHPTAK
NVHDVDSIQLIKIVKDMRDDRKFACGEEIKEHEPRFFIGAAANPFADPFEFRVLRLEKKI
KAGADFIQTQCIFDMERFERFMALVRERGLHKKAYILAGVMPLKSAKAARYMQKSVAGMI
VPEEIVARIEKASDPREEGVAICVEQIKHLRNIEGVAGVHIMAVMWEEIIPTIVKEAGLY
PRPSVD
>A0A436BWF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.08.2.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A436CLZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.08.2.1|TrEMBL
MNDMRQELIQTRGSATFAFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLATAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLEICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWLRVNER
>A0A3B0MDL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibaca ekhonensis|TrEMBL
MSAPRISFEFFPPKSLEASFKLWDTVRMLAPLGPEFVSVTYGAGGTTRQLTHEAVTTIGK
QFDLNVAAHLTCVDATRAETLAIADSYAKAGVSEIVALRGDPPKGQGGFTAHPDGFANSI
ELIEELAATGNFNLRVGAYPEPHPEAADTLADVRWLKRKFEAGAHSAITQFFFEPETFLR
FRDTCAREGITGQIIPGIIPIENWSGIRKFALETGTTVPAWLDDAFDKATRDGREDLLAM
ALCTEMCDRLMREGVEDLHFYTLNRPHLTRDVCHALGVQHHVALENVA
>A0A5C4J8B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura soli|TrEMBL
MPRLRPDRPPAVRELLASGARSFSFEFFPPKTDKGARNLWRTIRELEPLHPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVNHSQAELRRLIGRFASVGVRNILAVRGDPP
GDPMGEWVKHPEGVEYAADLVRMIRSYGDFSVGVAAFPYKHPRSPDIESDTRYFVEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDVPILPGIMPVTQISTIERSEQLSGAPFPPEV
KARFDAVADDPEAVRRLGIEHAAELCQELLDQDAPGIHFITFNKSTATREVYGLLAPLEG
AGGYGAGGRVPPMTA
>A0A4P6VYN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rheinheimera sp. D18|TrEMBL
MAFANAQYLDAINRNLQDIAGKVNVSFEFFPPKTAQMEQTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASKDELVAIAKDYWQSGIRHIVALRGD
LPAGSIGKPDLYAVDLVHILRSVADFDISVAAYPEVHPEAPNGQFDLLNLKRKVDAGASR
AITQFFFDIEKFLRYRDRCAAIGIDVDIIPGILPVTNFTQLQKFAGLTNVAIPQWMYKAY
DGLEHDATTRNLVGVNIAMEMVKVLSREGVDHFHFYTLNRSELSYAICHLLGVRPAIAA
>A0A4Q9YDE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVVAKETIQRPKVVH
THEKRSRAHVTLAEKAKEQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A847Y7Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermogutta sp|TrEMBL
MTDEPTLPAGNPDHPQHEPASPETPPTAFRRSLEGGAFVYGAEIVSTRGLPAEAEKLPPA
VLARELAGDPRIAWVSITDNPGGSPMLPPDGLAALLPGAQGKVVIHLTCKDMNRSGLESY
AWRLAARGLWNVLALTGDYPVTGFGGRPTGVFDLDSVGLISLLAAMNRGLEIPGRKGGPE
RLRPTAFYLGCAVSPFKRHERELVPQYFKLVRKIAAGAQWVITQLGYDMRKFHEVKLFLQ
ARGIGNVPLIGNVYVLTKGIAKVFHSGRLPGCVVSDELLALCEKYGGGPDRGAQFFRELA
AKQLAVFKGLGFAAGYLGGLNSPDAFFRVIELAESFGPDDWRQFLPEIRFSLPGEFFFFE
HDPETGLSGPDRINREYLQSLERPRGNRAVTLGYRISRLVHRWAFTRDRGLWGLLRRLYA
RWDKRPSSLPAKAAYAVERFSKFAMYGCQDCGDCSLPDCAYICPKRWCSKCSRNGPCGGS
SDGQCELQDKECLWAKAYQRLMAYGETDRLLDGPPVIYNAELQHTSSWANTFLDRDHHAR
RAEPGGKD
>A0A4P5UV67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobi bacterium|TrEMBL
MSKTKVQFSDIVGVKPIVTSGSIEIELQSRGYKDFPVEVYNLKNPVIIEHIYRDFLIAGA
TLLLTNTFHANRITLEQAGLSDKVYEINRKAVWIARTVALQNAYVGGVIGPTEKFFVPIG
TLTEDEALQVFIEQAVALIDGGAELIMLKSFIDIDELEIAIKAVRSVHNDIPIIALKTFP
EDGSVLATSYPSDIAYRLEKYGVLAIGSSGTVGPQRMCDIIRALSVTSIPLCALPEIAIP
TLVDGRAVYNAEVDYVASVAVSLVQGGACIIGADGGASVQHIKAISDAVTNQIPGSSKYI
PKLIKEVNTLAIDSDKVSSFAEKIGKKFLTTVEVEIPRGLDISNVIQAASYLKEQGIDAI
NVFDGARARVRINPIAASYMISSATGMECITHIACRDRNMVGLQSDLIGAYALGVKNILA
VTGDPTSIGDYPFATSVYDVDSIGLVRAVNRMNHGMDLMGNPLGRSTRFLITCAANPAAD
DIEREIKRLEKKAQEGATMYFTQPIFDIKTLEYFLDATKHLSMQCILGIIPLRSIKHAEF
LHYEVPGMVVPDWVRKKLKDVNTDSGIEGMNIAIEFLKQAKGLVQGVYIMPPAKKYDMAI
NILHAADIL
>A0A6S4QHS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MKSIPAPTVPEVLAKAKATQSTYLSIEMIPPVRGEGITAVFNTLDVLMSAEPHFINVTHH
SAERVLILHEDQWIEKTISKRPGTVGICAALIQRYPKAVPIAHIICTGTTTEMIENNLID
LNYLGIRNVLALRGDLPKRIKAHTTTPTTNSVNAALPSPSRTGSSLADPQSPASLRHKYA
ADLIKQIKNLNQGIYLDPTLITTTPTHFSIGVAGYPEKHIEANDELVDINYLKQKIELGG
AYIVTQMFFDNAKFFAFRDRCLKAGITVPIIPGLKPIATRKHLDILPKVFNISIPQELSH
AVKTASSPEAVFNIGIEWCVNQCLELKKNGVPMLHFYTMNRSRNIEKIFKQVF
>C2Q0V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKRLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6C0TM59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. OIL-1|TrEMBL
MTTEQNNPISFEFFPTKTDAGHEKLIAAAHVIAAEKPEFFSVTYGAGGSTRDRTVNTVLQ
LDQEVKIPTAPHLSCVGDAKEDLRSLLNQYREAGIKRIVALRGDLPSGMGQASGELRYAN
ELVEFIRNETGDHFAIEVAAYPEAHPQARHFEADLENFIRKARAGADSAITQYFFNADCY
FHFVERVRKAGVDIPIIPGIMPITNYTKLARFSDSCGAEIPRWIRKQLEAYGDDSASIAG
FGTEVISHMCERLLDGGAPGLHFYTLNQAEPSLAVWRNLGRS
>B4D0K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacter flavus Ellin428|TrEMBL
MQFIRDIYAEARLAGRPVLSLEFFPTKTEEGERNLLEKTLPDLMSIKPAFCSVTYGAGGG
TRDKTLGIVDRIQRHHNLPAMMHLTCVNSTREELGHVLDEAKGRGIQNILALRGDPPSGG
DFVKTEGGFEFSRELVSFIRERSGFSIGTAGFPEGHIAQHAGKLVDWQYLADKIAAGADF
VVTQLFFDNADYYEFYDHLVGKLGVTVPIVPGIMPILTAGQTRRFVSLCGAKLPAQFLRR
LDELDGDDEAVAAYGIEYATEQCASLLEFGVPGLHFYTLNKARSTVQIVRNLGLLNA
>A0A368EIP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|PS1 clade bacterium|TrEMBL
MTSISLEFFPPKSAETEAKLWDVINELAVIRPDFVSITYGAGGSTRNRTHKCVKHLVTKT
DLKPAAHLTCVAASKSEVDEVIEDYAVAGVKHIVALRGDMPDMEAFSPHPDGYRGSVELV
DALSRRGGFDVTVSAYPEKHPESGDMQTDIDLLKAKIDAGATRAITQFVFDTEHHYRFRD
VLADNQINIPVIPGIMPTTNFKGVLRMSEACGASVPDWMKSKFEGLDDDLESRRALAIEV
ATEQCRDLIKSGFENLHFYTLNQATVTQAVCNALSLENVGVQ
>A0A316Z188|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tilletiopsis washingtonensis|TrEMBL
MVTATNTPPSPALASPGSGRQEADTDWRITTKIAKAEAEGRVWWSFEYFPPRTAQGLTNL
YDRIERMADLGPAFVDITWNAGGRTSDLTAQLVKTVHTYIGLETCMHLTCTNMPRSKVDV
ALREAKEFGCRNILALRGDPPADGGAWQRHEAGFEYAKELVEYIREHYGDYFAIAVAGFP
EGHPEAQEGRDLEMERLKEKIDAGADFIFTQMFYDYDIFERWVKSVRAAGITCPIVPGVM
PIQTYGGYQRATARFRTEVPQYFHDALDPIKDDDAKVREVGTKLVGDMCRKIVDPKNGLG
ISGLHIYTMNLERGSRMLLDYLGLSPSVQQTKTLPWTPSLTPKRRDEGIRPIFWANRAKS
YVDRTETWDEFPNGRWGDARSPAYGDVDAYGVKLRYSNTEAVELWGKPESLDNVRDLFTR
FCEGKVKALPWSETGIAKETSVIDEKLRAMNRRGYLTINSQPAVDGARSDDPVHGWGPKH
GYVYQKAYLEFFVAPDQVDALISRIERDPQMTYHVVNARGDMRTNTTSEAPCAVTWGCFP
HQEIVQPTIVESISFLAWKDEAYEIGRHWARVYEEGSATRQLLEQLFDGWFLVNVVHNDF
KNADAIFAPFLGDEAPAA
>A0A660U5S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MSKLQESLQEGKFTITGEIGPPKGVDLTHCWQEVEYIKDRVVAINVTDNQSSVMRISSQS
ICALLVQKGLEPILQITCRDRNRLAIQSDILGGYAQGIRNILALTGDHNTAGDHPESKPV
FDLDSVSLLTAISKLKSGRDLANQELEGTPSDIFAGATVTPGADPLEMQLIKFERKIEAG
AQFFQTQAIYEPKVFETFMNKVSKYGVPVLCGIVIIKSPGMAKYMNNFVPGVFVPDSMIK
PLAEASKEDRPKRSIELMAEFIREIRPMCQGIHIMAMGWEKYVPQLLDMCDL
>A0A4R5F190|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Antarcticimicrobium sediminis|TrEMBL
MTAPAISFEFFPPQNLQASFRLWDTVQVLAPLDPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLKVAAHLTCVNATKEETLEIADDFAKAGVTEIVALRGDPPKGEGKFTPYPGGFANSI
ELIEALAATGKFSIRVGAYPDVHPEATNAQADIDWLKAKIDAGADEALTQFFFEADTFFR
FRDACDKAGIDAAKITPGILPIENWKGARKFARSCGTTIPQWVEDAFEKAMRDGREDLLA
TAICTEMCSALIEGGVDRLHFYTLNRPELTRDVCHALGVTPKVSLENVA
>A0A660SVN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MLIKEILIEGKTAVSYEFFPPKNPLGWEKLYQTITDLNHLNPAYISVTYGAGGATREHTH
KLVTQLVRETDAEIVAHLTCVGHSRDEMKSILDRYAESGVHNILALKGDTPSDRIVGRSK
PPGAFPHASDLVFFIKDNYPGMGIGVSGFPEGHPSSVNRLEELVFLKEKVDAGADYIVTQ
LFFDNRDYYDFVDRCIIAGITVPVIAGIMPVTGLSNMNHMAKLAPRTRFPSGLIRAVNRA
ETDEGVEMAGTHWATEQMRDLLDRGAPGIHLYTLNNSASTIRMGESLGLVGFHNLR
>A0A6P2AW57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirulina sp. DLM2.Bin59|TrEMBL
MSRLRRAIAAQEFLITAEVMPPKGGDPHHMLAMAAGLKGRVHSVNVTDGSRAVLRMSSLA
ASMVLHQAGIEPICQMACRDRNLIGLQADLMGAHALGLHNILALTGDPVKAGDHPQARSV
FDLESVRLLKLIQQLNQGFDANGKPLTDGHLDLLVGAAVDPQLPSWSSLQRRFERKVEAG
AQFFQSQLICDFDRLEKFMTQIAAMGDRPILAGIFLLKSAKNANFINRYVPGANIPQTII
DRLAAAADPLTEGVKIAAEQVKLAQNLCQGVHMMAVRREDLIPEILDRAGIAPIEV
>A0A3P7IGJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strongylus vulgaris|TrEMBL
FFSGNASFGSPKFPFLQFFKVGHGNKYVPLHERINRRIKDGTPFFSLEFFPPKTANGVAN
FFTRHVYCFLKLFLKSLLRFRLDRFNEGGPLFVDITWHLGSDPGRNLGIHYMLRLEIQYH
FFLVVCEKSAKSVLKVPLSANMTKETSSSSIAAGCLDYCRVDTMLHMTCAQYSKEQTIKH
LEQSKSVGLRNILALRGDLPNIERDDAPIYKYRALDMIRWIREEFADYFTIGCSGEIICN
YFMRIVIFSLEFSFLFLCIIFF
>A0A6M4H3R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Usitatibacter rugosus|TrEMBL
MSEPVNRRDQRLLSFEYFPPKTPEGMEKLRAATRQLAQLKPDFFSVTYGAGGSTREGTLA
AVQTIRAEGHEAAPHVSCIASTRESIHEVIETYRANGIRRVVALRGDLPSGMAMAGDFRY
ASELVAFIREKTGDAFHIEVACYPEYHPQARKPQADLAAFKAKVDAGADSAITQYFFNPD
AYFHFVEQCRAMGIGIPIVPGIMPIQNFSQLARFSDACGAEIPRWMRLKLEGFGDDSASI
KAFGLDVVTDLCDRLLSQGAPGLHFYTMNQAGPTSTIWQRLGL
>A0A849UXW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloglobulus sp|TrEMBL
MQSQKKHPQLFSFEFYPPKTQEGAAGLQVVHSKLAALNPDFFSVTFGAGGSTRDLTFDTV
VDIQSKGIAAAPHLSCVASTKENIRAILKNYQDHDISRIVALRGDLPSGMMSAGEFRYAN
ELVEFIRQETSDSFQIHVAAYPEVHPQATSAAEDFKNFKRKVEAGANAVITQYFYNADAY
FYFVDTCEKNGITIPIVPGIMPITQYSQLFRFSEMCGADIPRWLRKRLEGFGDDRASVQA
FGLDLVSDLCRRLLDGGAPGLHFYTMNQSAPTLSILERLNP
>A0A1S9ZPE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella canis|TrEMBL
MTHTLDRLTAIEQLLGELKNDLQATPSHTSSQAKTTKVPFSFEFFPVKTDDGQVKLMKTF
DELNALNPTYFSVTYGAGGSTRARTLGIVEALIQQSNTPIAPHMSCIGDTKSEIAELLEF
YKSLGVDRVVALRGDLPSGQVGYGELPFALDLVKYIREHSGDYFSIKVAAYPEMHPQAKN
FEADIDNLVAKYHAGANEAITQFFYNPDSYLYLRDRLAKKGVHQDDFPIIAGIMPITNAS
NIIRFADACGADIPRYIRKQLADFGDDRKAIRAFGYDVVHHLCERLIQEGVPALHFYSMN
NTEPNKTLVTELGLI
>A0A2U3A309|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Act143|TrEMBL
MALGTASTRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVAHPQGLRYAAELVELIKNSGDFCVGVAAFPAMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVAAAGCETPIIPEIMPIASVKTLARVPSLTNAAF
PAALKERILTAKDDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A5K7YMZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina alkanivorans|TrEMBL
MHLKNKFDVGKFTIIAEMQPPKGVDISAMVNSATRVKKAVDAFLVPEMGNAVMRMSALGG
AMILQGKGLETILQVNCRDRNRIALQADLLAAYGAGIINMMGVSGEDPALGDHHQAKAVH
DIDLMTLFKAVATLQTGRDMAGNELSGAPAFLVGASVNARATGDELEKELDLMAEKADAG
VDFFIAPPVFDINAIAPFMEKADLKKNRVVPTVMLLKSVGMARYLARHLNMTISNDLIKR
IMRAPDKPLESLSIATEIISAAKEAGFAGVMISAMGWEDKLQKLLDMV
>A0A1F8R3C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_58_8|TrEMBL
MVSRFKEALDSGKFVITSEVAPPKGTNLEKMLHHIDILKDRVDAINVTDHQSSVMRFPSL
GGCLAIKERGGEAIMQMTCRDRNRMALEADLLFAYSRGVRNVLCLTGDAVPVGDHKEAKG
VFDLDSLQLLKAIRLLTAGQDLGGNKLEGAVEFCMGAIVTPEAKPIEPQLIKFEKKVEAG
AEFFQTQAIYDLDNFGKFMQYARRLNARVLAGIVLLSSARMARYMTENVPGIFVPQPLID
EMAGVPKEQMLAKGIEIAGRTIAVLKKGAICDGVHIMAIGKEEVVPDILAAAGL
>A0A5K7YX08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina alkanivorans|TrEMBL
MLNEPFTVTIEVVPPEGPDPAKVLAALESVARLPFFGFSVASNPVAKPRMSAMALCAMIQ
QRTMKPAILHLTTRDHNRLSLQGELWGARAMGIETVLVATGDFVALKDRGHTTTVRDADI
YSLVGMAREAGLHTGVVFDSHPESDGLNRAADHLKRKVDAGAQFAVTQPLYDEAGADEIA
GATRDIGIPVIMGILPLRTPRHAEFLHTRVAGIAVPELLRQRMHDAADPVAEGAANAREM
LAAARHRFAGACIMPPFDHYEVMFHIL
>A0A352TKW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKIAPLFSEKTVFSFEVFPPKKTSPIETVYQTLEELQDLHPDFISVTLGAGGSGNGENTI
AIARRLQEQYGITSMSHLPCIHCTKEKIDALLETFLESGIENILALRGDRVPELEPEHDF
AHASDLITYIREKHPNFDIAGACYPECHTEATSLEEDIANLKKKVDAGATHLISQLFFDN
EAFFHFQAEARKAGITVPIEAGIMPVTNSKQITRMVSMCGASLPRKFTRIIQKYEDNPTA
LQDAGIAYAIAQIIELLAAGVDGIHLYTMNNPYVARKISEAISGVLRATQR
>A0A2D9DVG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudohongiella sp|TrEMBL
MDIKNPDARFSFEFFPPRTDAGMEKLMIVHQELAALRPDFFSVTYGAGGSTRDGTRQAVT
KISQAGSAVAPHLSFGGSSKEDILALLESYREMGINRLVALRGDIPSGTGAASQYFYANE
LIEFVREKTGDHFHIEVACYPEIHPQSDSYDSDIHFFKKKVDAGANSAITQYFYNPDAYF
YFVDNCEKAGIEIPIVPGIMPITNFTSLQRFSVNCGAEIPRWIRQRLQSYGDDVESIRAF
GAEVVLHLCEDLLAGGAPGLHFYSMNQTEPVRQIWQQLDLR
>A0A222VTW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella marina|TrEMBL
MRRVVDRLGNAHRPTFSVEFFPPRDEQDEAVLWRSIRELEPLDPAYMSITYGAGGSSREG
TIRNIARVATDTTLVPMAHLTAVDHSVAELRNVIGHFAAVGVHNILALRGDPPGDPMGDW
VAHPQGLNYAEELVRLIRELGDFCVGVSAFPYGHPRSADLDIDTTYLVRKLRAGADFAIA
QLFFEAEDFLRLRDRVASAGSDALLLPGIMPLTTPKTLRKTIELSGATPPRWLTDRLEPL
SGDAKAFRAAGLDVVTELCERLLDEGVPELHFYTFNRSKATRELVDRLGLRSPAPPLAVS
APS
>A0A1S8ZY68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. KBS0721|TrEMBL
MKVTQHIENAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
VMALRGDAMKDEQYFIPKAGGNDYAVDLVKQINLLNQGKYLHEVMDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFTFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDQCKNNAEIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASHLF
>A0A174HNA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides caccae|TrEMBL
MKVIDLINNSKKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEEAPNIESDLYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAERVGIEWCVTQCKELMSHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A2N6S9V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIHSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKISEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A1C5MJD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MKLSEKMKEKQLLSFELFPPKTEKGMANLPGTIEHLMEFKPEYISCTYGAGGGNVGANRE
VCQMIKKAGSIPVTHFTVIKNTKEGIREQLDQYLEEGVDHMLALRGDFPMGETSTMGDFD
YATDLVKFVRDQYGDKFEIAVAGSPEGHISCRSLEADIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGVTMPVDVGVMPILDQAATINMALSRNGCVMDRELSRLISRHWLFPN
PFAAKDAEGKPFDLFYDKKIAEFKEEGIEYTIRQIDTYRALGVEGIHLYALNKWKDVSEI
INRSGLRTLV
>A0A173YYM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia wexlerae|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A7W1RRI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MRIDQILEERRPVFSFEFFPPKDDEGMERLFNAVAELKKDDPAFVSVTYGAGGSTRDRTI
AVVKRIRRELDVEAMAHFSVVGATREQLVTTLDEMQDAGIDNVLALRGDPPKGETEWRPE
PGGLVYSSELAALISESYPFCIGAACFPEVHPEAESMSADIDFLKEKVAAGARFLITQLF
FDNDFYFDFVEQARDAGVTVPIIPGIMPITNFKQIKRFTEMCGASIPEPLEQALAARAED
DGTGVSELGVAYATLQCTELLARGAPGIHFYTLNKSPATRAILGALRAARPWDRALSPA
>A0A4S8TAX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVNVTWGAGG
STSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILALRGDPPRS
DEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQSHPEHQHA
TYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGLMPIQSYQ
ILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSGPKGFHFY
TLNLEKAVAHIVERCKLIGAVNNVTVEDHDTPVANGNGDKKAKARRRSSIANSAPQNRVV
IDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIPWSEEGLN
PETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVEFFCSHED
WTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIEAVSFRAW
AEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLLEA
>A0A348SZT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MQISQMFKRKPCVFSIECFPPKQTANFGKMKDTLRTMRTLNPDFISVTYGAGGSTGGVST
VEVAEFLKNDLNVEPLAHMICMGSDKAKAAQLLDQLNAAGVRNVLTLRGDRTPTRPESPD
FAHASDLAQFVWQTQPEFDIHAACYPEGHPEAATLAQDVANLRFKQEAGATHLLTQLFFD
NMHFYRFLNLARRAGITLPVSAGVMPIVKRSQIERTVALSSASLPSEFTRMISRYQDDPE
SLYAAGIDYAVQQLRDLIEGGADGVHLYAMNDAKVAAAVYEGIKDLL
>A0A090GVC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium plurifarium|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDTVIREFADMGVKRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A0V1J3W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella pseudospiralis|TrEMBL
MAIILQSALLVCISVYCLMIFFYSNNYVVFFPILCYPTGHPDASSYEEDLLNLKAKVDAG
ADFIITQLFFDEMHYFKFVNDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSKIVIPDSVL
TTLESIKENAEAVRNFGISFAVELCRKLLNAERHVVPGLHFYTLNQEKSTRSILEQIGLW
KESPVRMLPWKKHPVHSVRCREAVRPIYWNTRPKSYLCRTRDWKQFPHGRWGDLGNPAFG
DLKHYLFSCIDQMNDSCALDMWDKELSSFEHVRDIFCNFIARTPNRHGHTVRRLPWNENH
SDPAVDVLKDELIYYNSNGILTINCQVAVNGLPSNDPIFGWGEANGYIYQKGYLEFFASS
KCTTILLNHVQNFPSINYHAINFDGSFETLNYDEDATMALTWGVFVGQEILQPIVANAAS
FRVWKDEAFDLWQRWARLYESGSIGRKLLQSIHDDHRLITLIDNDYPQPCSLSALLRAVI
DECCEEKKIDDE
>A0A2G1XNP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cinnamoneus|TrEMBL
MDSHTASPGGAAGLLLEDFSLEMTGKDGPALEEAGHLLPAGTRVNVTFLGNEEMSTRLTA
ARAVKALGFEPVPHLSARRMPSRAAFEEFLCRLRADGTSGQVFAVGGDPAVPEGPYEDSL
ALIRSGLLERYGVQQVGLCGYPEGHPAITGPRLWSALEQKAAALSERGMSGHVVTQFGFD
PDPVLRWIEEARDRGVHLPVRVGVPGPAGVRRLLGYAARFGVGTSAGIARKYGLSLTHLM
GTAGPDRFLRALSEGYDPQRHGTVKLHFYTFGGLRATAEWAAGFREASPSAS
>A0A8B7VZ90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Castor canadensis|TrEMBL
MAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRREEITSHL
QKAKQLGLKNILALRGDPTGDEWEAEEGGFNYAADLVKHIRSEFGDYFDICVAGYPKGHP
EAGSFEDDLKYLKEKVSAGADFIITQLFFEADTFFHFVKSCTEMGITCPILPGIFPIQGY
SSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGQVPGLHFYT
LNREMATTEVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQDWD
EFPNGRWGNSSSPAFGELKDYYLFYLKSKSPTEELLKMWGEELTSEESVFEVFASYLSGE
PNRQGYKVTCLPWNDDPLAPETNLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGP
SGGYVFQKAYLEFFTSRETVEALLQVLRKYELRVNYHIVDVKGENITNAPELQPNAVTWG
IFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGKLYEEESPSRMIIQYIHDNYFLVNLV
DNEFPLDNCLWQIVEDTFELLNRPARNEQETATP
>A0A2V5XN49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIIRGNSPTFSFEFFPPKTPKAAETVYQTIRDLELYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLEPIPHLTCVCHKEDEIEEILLRYAKSAIGNILALGGDRPAGIAYDKSR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFAEGHPATPNRVVEMDYFKTKVDAGA
DYIVTQLFFDNRDFLDFRERCALNEIHIPIIAGIMPITSISGLKRIAELAGGARFPAKLL
RALQHCQNDPEMVRRVGIQYALEQCRDLLDNNVAGIHFYTLNRSDATRVIVDRLGIPRRQ
NAQTASV
>A0A8D0MGC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MEKLESSAMVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRM
ESGDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIA
STAVNYCGLETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGDPVGDQWEAEEGGFS
YAADLVKHIRSEFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEA
DTFFRFLKACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAA
IRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSA
HPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSP
KEELLKMWGQELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLR
VNRRGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYE
LRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIE
QWGKLYEEESPSRMLIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEP
EASDPAP
>A0A2V6J140|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRGGSPTFSFEFFPPRTPQAAEILYHTIRDLESYMPHFVSVTYGAGGSTRELTH
HLVERIQHTTKLDPIPHLTCVCHNEEEIEAILIRYAKSAIGNILALGGDRPPEIEYDKWP
NSFQHAIDLVKFIRKFNESGAHPDQRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVGAGA
NYIVTQLFFDNRDFYDFRERCALAGIHVPIIAGIMPITSMSGLNRIAELAGGTRFPARLL
RALQRCANDPEMVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRIIFDSLGIPRRS
NAQAQSV
>A0A250Y3W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Castor canadensis|TrEMBL
MVNEARGSGGPHPRSEGSSSGSESSKDSSRCSTPGLDPERHEKLRDKMKRRMESGDKWFS
LEFFPPRTAHGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCRQRREEITSHLQKAKQLGLKNILALRGDPTGDEWEAEEGGFNYAADLVKH
IRSEFGDYFDICVAGYPKGHPEAGSFEDDLKYLKEKVSAGADFIITQLFFEADTFFHFVK
SCTEMGITCPILPGIFPIQGYSSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEL
AVSLCQELLASGQVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPTEELLKMW
GEELTSEESVFEVFASYLSGEPNRQGYKVTCLPWNDDPLAPETNLMKEELLRVNRQGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLRKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQIVEDTFELLNRPARNEQETATP
>A0A6H3ASK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus anthracis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A069Q923|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A8D1R6C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MDRPKAKGLPAGQCCPSLGVRALEAGISRSSVPPAISRSSAMVNEPRGNGGPGPRCEGSS
SGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEVTG
YLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACSEMGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMLIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>A0A821TSB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood1|TrEMBL
MTLTHTEKSTASNHCDVHQNGIDNRKMSNSSDYFGEFKHSQSEHTLLKTRANSLLPVKYI
SLTEKIQKRIANNDRWYSLEFFPPRTTNGAVNLIGCLERMAVSEPLFCDITWHTAGDPAG
TKETSTMMIANTMLNYCNIDTMLHITCYGAKKATMIEYLSKAKDFGIRNLLALRGDPPVG
EKWDPEKTDFRYASDLVKFIRENFGDYFVICVAGYPKGHPDSKTYEEDLHYLKEKINCGA
DFIITQLFFQAETFLKFQSDCQAVGITCPIIPGIFPIQAYASFKNIVRLTKLDVPDEITA
HMESIKDNDEAIRDFGVQTCVDLCKGLLDSGKVHGLHFYTLNREYATSEILKQLGFGFED
PPLRALPWKKTSKNHVRSKEDVRPIFWSTRPKSYIHRTSDWNEFPNGRWGISSAPSFGLL
TDYHLFYMKIDATRDELLDEWGHELTCEQDVWKMFVCYIGGKKNSSDKILRHFPWKDEEI
SPETNLIHNELVEYNRKGILTINSQPVVNGKPSTDPIFGWGERNGYVYQKAYLEFFTSAN
NIPALRAVLKNFPGVNYHFVNKSGEVNETNADDEQPIALTWGVFPGREIIQPTVVDPVSF
MIWKDEAFGLWMERWGKLYEPDSRSYSIIEQISNTYFLVNLVDNDYPQGSCLWAVLDAMF
EYQQKTNQDINR
>L1IVS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Guillardia theta (strain CCMP2712)|TrEMBL
MKIVDRLKERNGAPFYSFEFFPPKTPSGVSNLYERVERLGKLEPLFVDITWGAGGSTSDL
TLELSSNFQRQFNLETQMHLTCTNVTKETVTQALQQAREAGIQNILCLRGDPPAGQEKWE
ATEGGFANAVDLVRYVRQLHGDYFGISVAGYPEGHIDWFKDTPEISEEDYRRDLQYLKDK
VDAGADMIITQLFYDVDVFLKWVKDCREIGINVPIVPGIMPINAYAGFNRMTGFCKTKVP
KAIRDGLEAIKDNEDAVKEYGVQLVTDMCRRLLDNGIPGLHMYTLNLEKSTVAILNNLNL
LKNTTSRRALPWRPRIGQKTEDVRPIFWANRPRSYNSRTMHWDEYPNGRWGDSRSPAFGE
LTDYHLTQVHTVDEADRKAAYGSQLSGVADVNALFAKFLKGEINRLPWCTALDVETNALK
ESLAKLCDSGFLTINSQPRVNAASSTDEVHGWGGPGGVVYQKAYIEMFCSPAHLAAIKAA
LPEHKSIQYSAVNTKGQYETSAKNKVNAVTWGVFPDREIVQPTVVDEESFLVWKDEAFGL
WLSQWKKLYEEGSSSAKVVQDIYDQYMLVTIVDNDFINGNIFAFMDSAVAKLGK
>A0A6J5DLU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia paludis|TrEMBL
MASLLIHPENPGSAGNITDAYSLEVTAKDIPALTAAAPRLLPASTISIPYLPGEDNDARL
AAARAVRRLGFEPMPHFSARRIGSLAELDAFVTRAVAEAGVERCFVIAGDPSTPMGPFSD
SSSLIETGIFERSGIKVVGVGGHPDGHPVMSTADRWDVLERKCDSIARRGMTPLIVTQFA
FDADIVLTWLQALRERGIEHPVRVGVPGPAGIAVLARYAALCGVSACASMWSKYGVSIGK
LFGTAGPDRFVDRLATGLTPAHGKVSLHFFPFGGIAQSLKWIEQYRSRAEPPRA
>A0A3T2ZR70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Schwarzengrund|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1H2JEE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fragi|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETADHFHIEVAAYPEMHPQARNFEDDINNFVRKAHAGADSAITQYFFNADSYFR
FVERVEAAGVMIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A072VS77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Medicago truncatula|TrEMBL
MKVIDKIRSANADPNKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANKMQNIICVETMMHLTCTNMPVDKIDHALETIKSNGIQNVLALRGDPPHGQE
KFVQTEGGFACARDLVQHIRSKYGDYFGITIAGYPEAHPDVIGADGLATAEGYQSDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILTS
LGLIEESKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWEQYPHGRWSDSGN
PSYGALTDYQFMRPRAKDKKLIEEWAVPLKSIEDIYERFRLFCLGKLRTNPWSELDGLQP
ETKIINEHLEKINTKGFLTINSQPAVNGEKSDSPIVGWGGPGGYIYQKAYLEFFCSKEKL
DALIEKSKDRPFLTYMAVNKEGIWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFNVW
KDEAFEIWSRGWASLYPEADASRKLVEEVGSSYFLVSLVDNDYANGDLFGVLADF
>N6UGD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dendroctonus ponderosae|TrEMBL
MEHQKNERTEFIKALLQETAEARWSLEISPSSELGCEVFQQLSPLFVAVTWLGNMNLEKP
ISDIAGIALAKKITQCNFPVLFHLCGRNISRRKMMEILDYLKRCKVRNLLALQGDWAHVL
ETDDTKCDFPYASDLVLFIKTHYPDDFSVGVAGYPDCHPHSRSLEEDLKYLKLKVSNGAG
FIITQASFDYDCLEAFADNCKKHDINVPIVPGFLIIKSY
>A0A1Y0YLZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus licheniformis|TrEMBL
MGFLEDIKNKTLIADGAMGTLLYSYGIDRCFEELNISKPEEIRRVHEAYVQAGADIIQTN
TYGANFIKLSRYGLEDETKQINEKAVRLARAAAGSAYVLGTLGGIRTFNKNSYSLEDIKR
SFREQLYLLLNEQPDGLLLETYYDLEEAREVLKIARKETELPIILNVSMHEEGVLQDGTP
LADGLKQLASLGADVVGINCRLGPYHMIRALEEVPLLEDAYLSVYPNSSLPSLVEGRLVY
ETDDEYFRESAEEFRNQGARIIGGCCGTTPNHIRAMAEAVKGLPPVTEKRVKIRKKAALA
VQNERTEPALDDLAKQKRSIIVELDPPKQLNFEKFLHAAEELKSAGIDALTLADNSLATP
RISNVACGALLKQRLDMRSLIHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRLE
KKIACGADYFISQPVYSEEQLIKIHEETRHLETPIYIGVMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGNDKQKQAEEGLAIARSLLDAACDLFNGIYLITPFLRSDLTAELTAYIH
QKEKEKTNV
>A0A3V5USS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Eastbourne|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>W2NNH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora parasitica|TrEMBL
MKVIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMAEADIKKALDEAKDAGIQNILALRGDPVRGASS
FDECDRGFSHAVDLVRYIREKYGNHFCIGVAGYPEGHVEIKDKKADIQYLKEKVDAGADF
VITQLFYDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTSFCNTFVPDEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRASESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSNTSTPRERRAMWGEAPAAKEDVRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGALSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
PSIQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEPGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSPATSP
>A0A2E8AUY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MKLGDYYQSGRMGLSFELFPPKTPAGEAALMKHCGALMEFHPDVVTCTYGAGGSTREKTL
EIVRQVKQKFGVPVASHLTCVGSTKQQLRDYLDAANRQQVDYIVALRGDPPRGEKKFRPV
SDGLSHANELVSLIRSEYSHFGIAVGGYPEMHQEAPDPHIDLENLKRKVDAGADIVITQL
FYNNEAFFVFRDRCDKIGLEVPLIPGILPVTNYSQVHRLASLCGANLPRRFVQALADCED
DAEQQFQIGVDYAIAQVNDLIQQQVAGMHFYVLNKSQAASAVLAALGRSEKTT
>A0A3F3RJK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus niger|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVEQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDTSSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A222TLW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia rubripertincta|TrEMBL
MRIALYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFMPPRDAEGEARLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSIAELRALVGAYADQGIA
NILALRGDPPGDPLGEWIAHPEGVEYAEELVHLIDTLGDFHVGVASFPEGHHRAPDLEHD
TRNLVNKLRAGAEYSITQMFFDVEDYLRLRDRVQAADPEQGAKPIIPGIMPVTSLASIKR
MAELSGSVIPPKVVERFTKAAGDGPEEDRATVRAVGIDFATETAERLIAEGAPCLHFCSL
NFAKATSEVLGRLGVDVDAALHVPA
>A0A212FC88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Danaus plexippus plexippus|TrEMBL
MSKITELISNSEKLSYSYEVTPSITYEKIKDIDILPRFFSVTWHPQEQDLKSFNMGFAPL
KLATDLITAGHNVLLHVSCSFMMKKYLHDLLKFLQEMGICNLLIIRGENYDATKSDFTSH
ELIKYIRKLTGDYFCIGVAGFLADDEKLPHLKAKVESGANFILTQAFFQPIMFENFVLQC
HEIGINIPILPGLFVFETKVQLNKFISLCKIRVSENTLVSIKKHSGIGTVAKLILDLNKL
SGIKHFHFFTINKMDITSKIIECVNSNMITNMNEV
>A0A0F6TA78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium camporealensis|TrEMBL
MSPRLSASAPLDQISYDDFEMPTRTALSFEVIPPRHDADAAKIDRLLATLDAYNPDYIAV
TSSQRSGWLEGTAQFIERISAQTRMRPLAHLACTAGDRQQLISWINRLMDAGVRGLLALR
GDLPPEGLPAHYLQHADELVRLIRQLEHQQAARFAAGRLAVGVACYPNGHAESANYDEDL
DVLLAKQRSGADLAITQLFFDPEDYLRFLQKARLAGVHIPLIPGIMPMTSLARLRRMGEL
SGLEVPQRVIDKLAAANSPEEEHDIGMELTAQLARTILAGGAGSLHIYTHNNPDITVELL
DRIGITHD
>A0A2Y9B541|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jannaschia seohaensis|TrEMBL
MPTPTVSFEFFPPKSLQASFRLWECVRTLAPLGPDWVSVTYGAGGTTRDLTREAVATLGQ
EFNLRVAGHLTCVDATRAETMETARGFRKAGVEDIVALRGDPPKGADRFEPHPEGFSDSV
ELIGALAADGFRVRVGCYPDVHPEAASAEADIAWLKRKIDAGASEAITQFFFDAETFLRF
RDRCAAAGIDAPIVPGLLPIENWEKASRFARACGAVIPDDLAQAFEVATRDDRADLLAVA
QASELADRLVGEGVEHLHFYTLNKPELTRDVCLALGLAARPALSRVA
>A0A0H3J692|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium pasteurianum DSM 525 = ATCC 6013|TrEMBL
MLRNKVLNRDTGIITYAITPPRKVNSEEKIIEISQKHMERIKNIDIDGLIIYDIQDEADR
LKDERPFPFFETIDPAVYGNEYMQDLNVEKIIYRCVGKYDERELKDSVNSGIQKDKFSVF
VGASSKEQKVKLKLSDAYNIGEILKDNLTLGGVVIPERHTQNGDEHIRLISKMNKGCKFF
VSQVIYNVEASKNLLSDYFYYCQENNIEMVPILFTLAPCGSLKTLEFMKWLGINMPKWLE
NDLIHSKDILDKSIDLSKSIFEELLEFALDKGIPIGCNIESLSIRKVEIEASVQLAKDIK
LLIEGKRNSFNVTL
>A0A3R8XWU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEAPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A3C0IPB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTDHIALAKDTLISFEILPPLKGKSIQSIYDHLDPLMEFKPSWINVTYHRSETMFKKK
GDGTFEKVEVRKRPGTVGIVAAIMNHYQVDAVPHFICGGFNMRETEDALIDLNFLGVDNV
LALRGDAAKNETFFEPEPGGHRYAIDLLKQIMRLNDGLYLDDDIRDGGKTKFCAGVAGYP
EKHFEAPNLEIDLQHLKDKVDAGAGYIMTQMFFDNQKFYNFVEACRNAGINVPIIPGLKP
ITNKKQLSILPRIFHVDIPTELSNEIMKCKTDADCELVGTEWLIQQSKELKQFGVPVLHY
YTLGKPKVIWNAVKELI
>A0A6B1WTZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A0C4UTD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria columnaris|TrEMBL
AYGIHLGTEMCKKILAHGIKTVHLYTLNLEKSALAILANLGLIDMTKIKRPLPWRPPANV
>A0A0N4XFP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nippostrongylus brasiliensis|TrEMBL
MVGVAEESELCNGHLPASGEPLKKIDSLSAFPYIGSANSLHERSSSEDEHVSFDVTQGAK
YVPLHERIIRRVNDKTPFFSLEFFPPKTANGVANFFTRLDRFNEGGPLFVDITWHLGSDP
ANMNKETSSSSIAAGCLDYCRVDTMLHMTCAQYSKEQTIKHLEQSKSVGLRNILALRGDL
PNMESDGTPVYKYRALDMIRWIREEFGDYFSVCCSGMSRSHCFCVQLLNIVVV
>A0A3L7NNX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MEARVSFSTLYGTGKFGLSFELFPPKSAESEVAMWQTVEDLMAFSPSLVTCTYGAGGSTR
GKTLDIVEGVHRKYGLPVASHLTCVGSSVDELREYLAEALDRGVSGIVALRGDPPKGETE
FRPVVGGLSYASELVQLIHTECPSLDIAVAGYPETHQEAMSEEMDLENLKRKCDAGGQAV
ITQLFYENSDLFRFRDRCESLGIHTPIVPGVMPVVNFSQVRRIAKLCKAKLPAEFINAME
KAGESESAQFEAGVQFATQQVHELVRAGVPGLHFYVLNRSPATAQVLQQVGISGKN
>G8YAU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL Y-12695)|TrEMBL
MRISEKLEQAHSSSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSTLTNDMVYVAQSTLGLETCMHLTCTNMKIELIDEALEKAYESGCQNILALRGDPPLD
GSESTGDFKYAKDLILYIRKKYGDHFNIGVAAYPEGHPEEGDDGRLLEYLKEKCDCGANF
IITQMFYDADNFINWCSQVRKIGIDIPIIPGIMPISTYSAFMRRAKWSQVAIPQHFLDTL
EPVKDDDYLVREKGTQLVSDMCRKLVESGYVKHLHFYTMNLERATIMILENLNLISSIKS
HEIVGGTDLPWRKSLHPSRSKESIRPIFWQKRKYTYISRTATWDEFPNGRWGDSRSPAFG
DIDLFATDLLRQSPKKAFDLWGCPQDLKDFSEIIISYLKGDLKSLPWSDSAIGEDSSIIT
DKLVSLNKKGFFTLNSQPSLNAVPSSNPVYGWGPKNGYVYQKQYLEFFVHKDIISSLIDK
MNAYNGAQGDRSAAVLTYYVVDAKGSLTTNAGDDDINAVTWGVFPGEEILQPTIVEKVSF
LAWKDEVYRLLSEWVKIYKSDIVKEFEIGEEKIKNFVNFLSGFAGEFYLCNIVNNNFMDE
NRTIFQLIEDLGIPNLA
>A0A212IRJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Citrobacter sp|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A6L8F8J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MALGASAEILPGQLPSPEVLASHLPRATSVYIPYPPKSRWPDTIAACEQALAAGMKPVPH
LPARSVRSAGELDDWLAGVVETGADAVMLMAGDRATPAGPYPDTPALLDSGLLAEHGLRR
LGVTSYPEGHPLIARADLDEALRRKMEYARATGSELWIVTQFVFSPSPALAWLERMRNAG
CTLPVRIGMPGPVALGALIGYAVRSGVVASARALKRKPGIARLAGRWSPTPVALALARHL
AGREDTASLGIHLFTFGGLADTAEWLSNLRTTDEVAVCPPETS
>A0A2A5FJ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium|TrEMBL
MRLDAMLKKTDQALISCEFFPPKTDKGEVNLWRCLNELQVIQPAYISVTYGAGGSTQERT
KRIVLGIKEKTGLSPVAHLTCVGSTQEQLGDLLNDYANAGIENILALRGDAPDGHDTFKA
VDGGFSHATDLIEFIHGRGDFSIACATYPEGHPESKGGIADDIRYLKMKQDLGAICAVTQ
YFFDNELFFRFRDAADKAGVTIPLIPGVMPILNYEQIVRFSNMCGTSISDQVHQKMQPIS
GDLVAVADMGVDLAVAQCRELLNEGVAGLHFYTLNKSAATIAIVNALGIAQG
>A0A661GA28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MLSMKKTLSKAEHNTLLHTVREAYMEVFPTSSIESKLDVLEPGSYIAVTCSPSKGVEVTL
DMVERLAQRGFKVVPHVAARMVRDDAHLREILQRLDDLPIISLFVPGGDAAKPIGKFSCA
LDLLRAISEFDHKLSEIGVASHPEGHPTISRDVLMKDLLEKQKYSNYLVTQMCFDANVLA
NWLREIRDLGVTLPAWIGLPGVADRSTLVKTSLRIGVGDSLRYLKNRGKIAANLLRSKSY
RPDELLADLAPYIADPSYNIAGHHIYCFNQVESAEQWRHEFLDALQSQD
>A0A182EUY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Onchocerca ochengi|TrEMBL
MDTITDHVTADDEAGTSTTKNDNGCVIDSSEITNQAAISSQTDWVTHGTYVPLRDRIKKR
IADGVPFFSLEFFPPKTANSVANFFARLDRFREGNPLFVDIAWHFGSDPGSL
>A0A291SN27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces malaysiensis|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRAELRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWISHPDGLDYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIGHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATELCARLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>A0A662LFQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MKYKSNLERVLVENNFAVTAEVGPPKGADADKVRVKGEILKGYADAFNVTDNQTAVVRLS
SLAGSVILLNMGLEPIMQVACRDRNRIAIQSDVLGAASLGIRNILFITGDHQSFGNHPGA
KGVYDLDSIQLIKVVKDMRDNGVFQSGDKIVAGKPDVFIGGVANPFAEPYEFRVDRLEMK
INAGVDFIQTQSVFNLERFNIWMDEVRGRGLDKRVHILAGVTPLKSLKMTERMKFHVPGV
DVPDDVYFRMKKAEDPQIEGFKIALELIDEIKKIKGVHGVHITALFWEEVIPRLVKESNF
LPRP
>A0A6I3MTQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSILREKLENTSEQVFTAEFPSIDGGGMVSVEKNAARLAPWFDAVNATDNPAAHAHTSNT
TTAIAMQMHGLEAIMQIVCRDKNRLAIQSDMMGAALHGITNISLLTGDDVTAGDEPEARR
VFDVDSAQAINIARIMATGQYLSGRKINPAPDFYIGAVENAAAPPCDYRIQRALKKHRAG
ARFLQLQICYHPDRLEAFCRGVAEVAPDLKLIPTVVLMKGAKGLSFMNDKVPGIDVPVDT
LKRVQSASDPSVEVNKLTLELAQHALTLPGVRGLHITDFRHDDTLAIFMNDLGRTPKRQG
>A0A3T2YI06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Panama|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A059W974|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albulus|TrEMBL
MSTLRADVTGPAPSFSFEFFPPRTEAGTRTLWRTIRRVEALAPTFVSVTYGAGGSSRDHT
VALTERIAADTTLRPVAHLTAVGHSVAELRHIIGRYSDAGVRDVLALRGDPPGDPDGPWT
PHPAGLTHAHELVSLVKDTGSFSVGVAAFPEGHPRSSDPDTDVRHFIGKCRAGADYAITQ
MFFHVEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAQLSHAAFPEELAHRLEAAR
DSPADGHRIGVDHATRMALRLLDEGAPGLHYITLNRSSAALDIHGHVCRSRSLHAC
>A0A384JNK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryotinia fuckeliana (strain B05.10)|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHHIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAAL
EEVKNDDAAVRNIGKDLVAEMCRRIIEAGVHHLHFYTMNLAQATRMVLEELSLTPSNQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLESGIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHEP
DLTYYAVKKTGDVQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLNEPFETSESGD
VDGVRFIEPQTVPLTNGEANGH
>A0A174WF96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi|TrEMBL
MKTTDLFAKKPVLSFEVFPPKRTNPVETIYETLDSLRKLNPDFISVTYGAGGSENCKATT
EIASKIKNEYGIESVAHLPCIGLTKDDVISLLGGFKRAGIDNILALRGDIPEGGRPAGDF
EHASDLISFIKEKEEFKDFNVVAACYPEGHTESENILTDIRSLKTKVDAGADHLITQLFF
DNDCFYRFKERALLAGIHVPVEAGIMPVTNKKQIERMVSLCGVSLPSKFTAMMERYEHNP
EAMRDAGIAYAVDQIVDLIARGVDGIHLYTMNNPYVASKIHEAVYRLLAA
>A0A229XBD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus turcosus|TrEMBL
MHVKDKLAENEAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALSAAYKAGCTNILALRGDPPRDKEA
WEATDGGLRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
VITQMFYDTDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFMRRATWTKARIPPDWLEAL
EPVKNDDAAVKEIGKRLVADMCRRLLAAGIKHLHFYTMNLAQATQAVLDELKLIPSEPLQ
RPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDAYG
IGLKGTNEQNIKLWGEPKSIRDVTQIFVRYLEGKLERLPWSDSPISSEANVIKDNLVQLN
SRGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNEDL
TYHAVGKKGELRTNTHDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRLGEDWAKC
HDAGSPSRNLIQDIMDNWYLVNIVNNDFHNTYDLFELFNGLEVKDLDVEIVPETVETKPQ
PNGAAPEAVAVKN
>A0A413RBZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium ventriosum|TrEMBL
MNIADLFKKEHTVFSFEVFPPKKESGIETIYSTLNELKNLNPDFISVTYGAGGKGVANAT
TIDLCSYIKNELGTETIAHLSCLYNTKESIDRILDELDEKGVKNILALRGDVNPDFAIEK
DFKYASDLTEYIMSKNRGFNISGACYPEVHQEAANMIEDIQNLKKKVDSGADHLISQLFF
DNQVFFDFQEKARIAGINVPIEAGIMPVTNKKQIERMVSMCGASIPAKLSKVLQRFGDNH
EAMRDAGISYAIDQIIELAAHGVDGVHIYTMNDPYVARRISEGVKNILKSGK
>A0A6J3JN41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sapajus apella|TrEMBL
MVNEARGNGSLNPCLEGSASSGSESSKDSSRCSTPGLDPDRHERLLEKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCHQRLEEITGHLHKAKQLGLKNILALRGDPTGDQWEEEEGGFNHAVDLVK
HIRSEFGDYFDICVAGYPKGHPDAESFEADVKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVRLCRELLASGLVPGLHFYTLNREVATTEVLKHLGLWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKNYYLFYLKSKSPRDELLKM
WGEELASEESVFEVFVHYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGVL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPGLQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYE
EESPSRAIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQHEREAEAP
>A0A1X1FQM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. tigurinus|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3U6BG33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5A8EG81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cafeteria roenbergensis|TrEMBL
MASAAAEAAAPSGAGSRPAAPAGGVRMVEGTTIPCGPPGNKIIDRIREVHAAGGTTVSLE
FFPAKTSKGVDNLLARIEGMTFRLRPTFVTLTWRSAFTDELLWLRIGAHVQREFGIDVLL
HLTCHLPVEDLKRVLRRCREAGIRNILALRGDPPIGQDKWTPCEGGLRNAVELVRLIREE
HGDYFCVAVAAYPEAHTECWNNPDLPPSEKARDLDLRRLKDKVDAGSDFIITQFFYDVDR
YLEFDRRCKAAGITAEMLPGYMPIQNYRGFAKFTKWCKTAVPPELMEAVREVRDNDEAVK
DLGVDDAVAACRRILAAGGRCLHFYTMNLSASISAVLDQLDLVPKAHEREAPWAASGPAR
SKDEVRPIFWSNRAASYLARTSEWDEFPNGRWGDFRSPAYGEITDYYLAFKRPKVKREAI
WGCPKDEADVRRVFVDFVRGKVPQLPWCDTPLADEAGAIADNLRWMNSHGFLTINSQPRV
NGAPSTDPKVGWGGDDGVVFQKAYIEFFVSPEQWEHLRKAMPAFPSLTYHAMNLAGEEHI
NTDRTRATAVTWGVFPGREILQPTVVDPVSFRVWKDEAFELWRSQWASAYPGDDEASVRA
REVIERIRSTWLLVNVVDNDYAEPESDIFSVFKHAATKAMSTDQLRAAVLAAEAENRALR
ERAEALQSHVARQSKDLEFQAERAARAEGEVAALRRRVRELEMRTVLAGSVASSLQPAGL
AAPRYLAATAAPGAAGAASAAASGAAVATVKA
>L2FEI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum fructicola (strain Nara gc5)|TrEMBL
MHIKAMLDETRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREHEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEELLLDHLKEKVDMGASF
IVTQMFYDADNFIRWVGKVRERGITIPIIPGIMPIATYASFLRRAKHMNCRVPDDWMAAL
EPVKNDDVAVREIGKGLVADMCRKIIAAGIHHLHFYTMNLAQATRMVLEELDYMPSSERP
LKHALPWKQSLGLGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSIKDVANIFVRYLETEIDNLPWSEAPLTSEADGIREELIG
LNKRGLLTINSQPAVDGVKSSHPVHGWGPPNGYVYQKAYLELLVHPDLFPEIVTRIEKNP
DMTYYATTKNGALTYNASSDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGTDW
ARCFEAGTPSRVLIDRIMNEWYLINIVNNDFHQKTALFDLLDGLSVQEYTDIPSEPKANG
ETELQNGTTGAAVTA
>A0A547ERM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mannheimia haemolytica|TrEMBL
MLWDSIDRLSPLKPKFVSVTYGANSGERDRTHSIVKSIQEKTGIISAPHLTGIDATPEEL
KVIAKDYWDSGIRRIVALRGDIPKGYDKALFYASDLVALLKSVADFDISVAAYPEVHPEA
KSAQADLLNLKRKIDAGANHVITQFFFDVESYLRFRDRCVSIGIDCEIVPGILPVTNFKQ
LQKMAAVTNVKIPTWMGKMYEGLDDDQTTRNLVAASIAMDMVKVLSREGVNDFHFYTLNR
SELTYAMCHTLGVRPDLTTA
>A0A497D8S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MEERVIEHIAQAESTLFSFELLPPLKGQDFSSTANAIDPLMEFNPSFINITYHQEEVVYE
NLSNGLIKKHTVRKRPGTVGIAAAIKFRYGVNVVPHIICGGFTREETENALIDLQFLGVN
DVLVVRGDPQVGMKKFIPEPDGNKHAVELVEQINKLNNGLYLDEELLNTRSMNFCIGVAG
YPEKHAESPNMDSDIHFLKKKIEAGAHYIVTQMFYDNRKYYDFEKRCRDEGITVPIIPGL
KPITTMDQIISVPKTFNVDIPAGLVKEMLKCKDNSQVRELGVEWAIQQSKELMEYGVPVL
HFYTMGKSDNIQKIAKAVF
>A0A353YGR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MLAAPERKSRFLGGGDIDVSFEFFPPKTAAMEETLWRSIRRLEPLDPRYVSVTYGAGGST
RERTHATVARILRETKLKPAAHLTCVAATRGEVDEVIRDYWDLGVRHIVALRGDPPGGIG
ERYVPTPGGYINAADLVKGIRAIAPFDVSVACYPENHPESPTVDAEIDMLWAKIDAGAST
AISQFFFDNEVFFRYLDRVRARGITIPIVPGIIPIHNFKQVSGFALKSGASVPEWLGHRF
EGLDNDQETRYLVAAAVAAEQVMGLVDQGITEFHFYTLNRADLVYAICHLLGLRPAAATA
KVEAAQ
>A0A0D8MUD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium leiognathi|TrEMBL
MSDQYLSSQESELRVRYNDITRGVYFIGTTPPKTSTPLEDVEGIADRLVDRICDLAIDGL
IVYDIQDEASRTNKPRPFPFKSTHDPRHYSSLLNKKTDKPVITYKSVVQSETEEFDAWLN
EAWDEYRVRDMVLVGSPSAKNEVSLPLSAAYQTLADNRNNFFTGGIMIAERHAKKGNEHE
RLIEKYKQGCNFFISQAIYDTQATIDILTRYAIECKEQGLKPQRIILTFSPCGSAKTLEF
IEWLGVSVPEATSLRILNAENPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRKE
EIDGSILLYKLLRSSMDSHLAKHEFRVLKRKARANKQASV
>A0A4Q8YI73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MALKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSQLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFEGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRSAAKSAGAAA
>A0A060B5M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas campaniensis|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLMHVRDELAARHPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
HFVEKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GTDVVSRLCERLLDGGAPGLHFYTLNQAAPVLKIVDNLRG
>A0A1S3ME44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmo salar|TrEMBL
MVNQVQRVEDTWRTCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKMGAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPDEIMRVIEPIKDNDAAIR
NYGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWNEDPRRTLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKNELDKVN
RRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPQEEQPAEQP
NDEQSDKEQPGK
>A0A335K4A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQTGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQSEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A1C3K680|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orrella dioscoreae|TrEMBL
MSLDTEKAAISLEFFPPRDLAAQERLVRTAKQLLAVQPRYVSVTFGAGGSTRDGTSGTVR
TLRNLGCDAAPHLSCIGASRDELRQILQGYRDEGVRRVVALRGDLPSGMGGDAGELRYAA
DLVAFIRAEFGDAFHVEVAAYPEMHPQAESPSADLRHFADKVAAGADSAITQYFFNADAY
FDFLDRTQALGVSVPIVPGIMPITNNTQLTRFSQMCGAEIPRWIRLRLAEFGDDKASLRA
FGVDVVSELCQTLLDNGAPGLHFYTLNSADAPLAIWRQLGLERAAA
>A0A1I2BCM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sunxiuqinia elliptica|TrEMBL
MKVIDIINNSDKTVFSFELLPPLKGNDASTIYRTIESLIDYAPQYINITTHRDEMIYKEL
ADGSIEKRTVRKRPGTVAIAAAIQHKYGIPVVPHILCGGFSKSETEHVLIDLNFMGISNV
LALRGDGLKSDHVFRANPDGHANASELVEQIVNLREGKYLEPDLKNNSPLDFCVGVAGYP
EKHFEAPNFDTDMAYLKQKVDAGADYIVTQMFFDNQVYYNFVDKCREAGITVPIIPGIKP
INLKNQLTVLPKIFSIDLPQELATELAKCKNNDDAKVVGTEWAIYQSKDLVANKVPSLHL
YTYGVSDNARKIVEAVF
>A0A1E3V4X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer alkalisoli|TrEMBL
MERTTLHPSERAEISLSFEYFPPKNEEMEAQLFQTVADLSAFAPAFQTVTYGAGGSTKAR
SLTTVRRMIGEMGLSNTAAHLTCVGAPQPEVDAIIEEFVACGVRHFVALRGDPQGGVGSA
YQPFPGGYENAAALVKALRARGDFEISVSAYPEKHPESRDAAADIDMLKRKVDNGATRAI
TQFFFDNDDFERYLDQVRRAGIEVPVVPGILPINNLSQVMKFAGLCGSTVPDAITSRLAH
LDDQPEERFREASHIAAEQIVDLVRRGVRDFHIYTMNRSPLVIAVCELLGYVRSPVNARE
MAVGSIKTAAGAR
>A0A3R9K306|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A078FXH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica napus|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRANGIQNVLALRGDPPHGHDK
FVKVEGGFGCALDLVNHVRGKYGDYFGITVAGYPEAHPDVIGENGLASDEAYQSDLEYLK
RKVDAGADLIVTQLFYDTDVFLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEVMAALEPIQDNEEAVKAYGIHLGTEMCRKILAHGTKSLHLYTLNMEKSALAILVNL
GMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALTDHQFSRPRARDKKLQQEWVVPLKGVEDIQEKFKELCLGNLKSSPWSELDGLQPE
TNIINEQLVKIISKGFLTINSQPSVNAERSDSSTVGWGGPGGYVYQKAYLEFFCSKEKLD
AVVEKCKALPSITYIAVNKGENWVSNTAQSDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFETWSRSWADLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIFSVFADL
>A0A534LNG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MRAGSRVERILAGGSFAVTAEIAPPASADASEIRRHAAVYRGTVDACNVTDGQRALVRIS
SLAAAAIVLQEGVEPIMQMVSRDRNRIGLQSDLLGASALGIHNVLCLWGDPPTAGNEKDA
KAVFDLSTEEMIATFREMRDAGTLRGGDKVEQAPKVFIGAAADPFRGSKEESFGKLRGKV
TAGADFVQTQGVYDVDAFEEWMRLVRKEWLHEKVYILAGVIPLKSAKMAQFMIEKLGAVV
PKHILDRMERAPNPKAEGVSIAVRTIKALKKIEGVRGVHLMPIGWEEVVPDVVKQAGLLP
RPDPKP
>A0A078GAF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica napus|TrEMBL
MKVIDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGSTA
DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK
FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYQSDLEYLK
KKVDAGADLIVTQLFFDTDMLLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCKTK
IPAEVMAALEPIQDNEEAVKAYGIHLGTEMCKKILAHGIKSLHLYTLNMEKSALSILMNL
GMIEESKISRSLPWRRPANVFRIKEDVRPIFWANRPKSYISRTKAWENFPQGRWGDSRSA
SYGALTDHQFSRPRARDKKLQQEWVVPLKSVEDIHEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLVKVNSKGFLTINSQPSVNAERSDSSTVGWGGPGGYVYQKAYLEFFCSKDKLD
ALVEICKALPSITYIAMNKGETWVSNTSQSDVNAVTWGVFPAKEIIQPTIVDPSSFNVWK
DEAFETWSRNWANLYPEAADPSRNLLEEVKNSYYLVSLVENDYINGNIFKVFSDL
>A0A7I6WPQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A4V3U3Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella oranienberg|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A535AT88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIAERLKRREPVFSFEFFPPKTPEAVERLYDTARRLKALQPTFVSVTYGAGGSTRQMTV
DLVTRMKRELGLETMAHLTCVGHTKEELAEVLDELAAGGIENVLSLRGDPPKGQTHFVRP
AGGFGYAQELTRFIKGRYAFCVAGAAYPETHLEAPDAETDLRHLKEKVESGAEFLITQLF
FEPDLYFRFVERARATGIDVPIIPGIMPVTNVAQIHRFTSMCGATIPSSLRDLLDRAKDD
EAAVIAVGVEWGRDQARRLLEGGAPGIHFYTLNRSHSSQMILDALRGD
>A0A6B0ZPX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MRNDSASLSRWEDPQPAGPNPDVQELIRNSAFEIIPLNSASEAIDALPPKSRVSITASAA
KGQAATLELAEELVLRGHHAIPHFSARLIRDRGQVKDLAEWAKYVGVTTAFVIGGDATEP
GPYHDAHSFMRDLFEYDHGLDTVGVAAYPDGHPLIGEDERRHALFAKQGLLAEAGLRGYC
STQMCFDPAQIIAWLKAERGDGLTLPVHLGIPGAVERAKLLTIGARLGVGQSLRYLHKNR
RSMAKLLGSSAHDPSELLEALSSQLTPLGINGLHIFTFNQVKTTAAWRQALIHG
>A0A179HZ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Purpureocillium lilacinum|TrEMBL
MHIKDMLSEAEKGAQPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLEKVNDALSRAYKAGCTNILALRGDPPRDQDK
WTATEGGFQYARDLVKHIRATYGNHFDIGVAGYPEGCDDNKNEEELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVGKVRERGITIPILPGIMPIATYASFLRRANHMQCRVPPEWMRVL
EPVKNDDVAVREIGKSLVAEMCRKLLANGIHHLHFYTMNLAQATRMVLEELNWAPSAERP
LQHALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTTVRDIANTFVKYLDQEIDSLPWSESPLTGEADAIRADLVA
LNKRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPPAIIDQMISRIDSKP
TLSYYAVTKDGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
AHCFDSNTPSRALIDKIMNEWYLVNVVNNDFHENHTIFELFKDLEVQGLDEAQAA
>A0A4R9INX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira bourretii|TrEMBL
MHISQILGKKQTTISFEFFPPKNAEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEETGLTIVSHLTCVGSTKDEIREILKRYQKSGIHNIMALRGDPPKGQTEFHKT
ENGFEFAGELVGFIKKEFPEMGVGVAGFPEGHPSTPNRLKEIEYLKWKVDQGVDYICTQL
FFNNNDFYDFVERCEIAGIKVPIIAGIMPITSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDVYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRRIYESLGIRNFDSIG
>E3GDX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium callanderi|TrEMBL
MTIPEIMKNRMCFSFEVFPPKEGQPLEPLLDTLDHLYAFKPDFISCTYGAGGTNAGRNVE
ICKAIKDSGATIPITHFTCIGNSKDKIRDELRNYLSLGVDHILALRGDFPKGSASTGGDF
NYANELIAFIKEAFPEFSIAMAGDPEKHFEASSFDEDIAHLRIKQDAGADFIMTQLCHDV
AHYEWWVEKIRKAHITLPVDVGIMPVLAKDPTIRMAVSNGSSIPRDLAEIIARYGDNPED
FKKAGMEYTVKQIHRFISAGIDGLHIYSLNKWADISEIVRAAGIR
>A0A6S7H3T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paramuricea clavata|TrEMBL
MLVQDTFESGVLTKRKCPSPSSGTSTPLSLIEKIKQSIGLEKKFFSLEFFPPRTPAGAAN
LIGKLEKFSSGSPLFCDVTWHAAGDPGGDKETSSMHIAGTILDYCGVEIMLHITCANETR
ETITRHLYKAKSMGIRNILALRGDPPHGEDFEVVDEGLVYGTDLVKHIRQEFGDSFTICV
AGYPQGHPDCSSYEEDLIHLKEKVDAGADFVITQLFFETKTFLKFVDDCREIGIDVPIIP
GVMPIQSYDSLRHLVKLSKLSIPQDLLDAIQPIKDDDKAIRNYGVDYTVKMVNELFSNGV
PGIHFYTLNREVATTEILKQTSLWSLEPLYARSLPWKPSANVKRIKEEVRPIFWASRAKS
YVHRTSEWDEFPNSRWGDSAAASFGDLSDYHLFYLRNRTKKETLLKMWGEQLTSVQDVYD
VFVCYISGEKNVNGTKVTMLPWNEDELAPETSEVSEDLVELNRKGVLTINSQPHANAAKS
TDPVFGWGGAGGYVYQKAYLEFFTRKEVVDKLLEVLGTNYPSVSYHVVDHTGEVDTISED
LASPVAVTWGVFPGKEIIQPTVVDPVSFQIWKCRCCAASFKWLDRNIIADFREESSFQIS
HLVVARVYKATFFTLHRVTEAFFLQCPPLRWNKWAT
>A0A1G9MWJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus equinus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLIHPEKVSAIHKAYIEAGADVIQT
NTYAAKRHRLKGYGYEDKVKEINQAGVRIARQAAGKDIFVLGTVGALRGLKQCELSLDEI
IQETLEQVNYLLETNQIDGLLFETYYDEEEIIAVLKAVRPLTDLPIITNIALHEAGITEN
GKPLVEIFGKLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAIKGLKPVSRKFVTP
MVEEAELIKAVKQSETIVDKVKRQVTVIAEIDPPKTLDIEKFTEGVKALDDAGVSAITLA
DNSLAKTRICNVSIASLLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDILGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIKQLNKGKGYSGASIKKETTFTAAAAFNPNVKNLS
RCSRLIDKKIAAGADCFITQPIFNKEIIENLAELTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDDFLEKIEAVKDDKNKCQELALQESKALIDSALECFNGIYLITPFMRYDLTV
ELVNYIHQKVEEKKQKIS
>A0A735VX02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. diarizonae serovar 48:i:z|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATGDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDIYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2A5MER8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella quasipneumoniae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A8E4DSS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas euroxanthea|TrEMBL
MTPLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSFGDDAEAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A736HL43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar 4,[5],12:b:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A090LG84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strongyloides ratti|TrEMBL
MPPNLGDPKNTEVNFSIDDDNLELKRNPSSVYSFYDESEVNTYIPLIKRINNQIESGVPF
FSLEFFPPKTANGVANFINRLDRFRDGGTFFLDVTWHTSSDPANLDKDTSSTSIARCVLD
YCRIDTMLHMTCTQYTKEQTLSHIKQCKDIGLRNILALKGDLVIDPNIPSEERPQSKYYA
LDMIKWIKEEYGDYFTIACSGYPLGHPSGESYEKDLEYLKAKVDAGADFIVTQLFFEVET
FEKFVNDCREIGINVPILPGIMPIQGYASIKRIAELSNLLIPQNILDDLEGIKHNDEAVL
KYGIDSAVKMCRYILDNKIAPSLHMYTMNREGPTREILQMLGLWKQYQIKHLPWKPHGGH
HPLRCKEDVRPIFWSARPKSYIFRTREWDDFPNGRWGHSSSPAFNDLKEYYMFYLNVSNK
EKEIQMYGDKLYSLEDIQNVFINFLKQQENENGIKVTCLPWNEDEKGVSFETNLIKDQLI
WANNNGFLTINSQPNVNGATSSDPIVGWGKQGGYVYQRAYLEFFTKKENAQKLVDIINSR
YNERINYHAIDKTGNYEMFNYNGTNPIALTFGIFSGSEVAQPTVVDPLSFRVWKDEAFDV
FNIWSSIYPPESKCRETLKYLHDNYILMTLVDNDYVKPTIIYDLLKEIVST
>A0A139MA62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A6B0XRM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MGTVLYESGVFVNQCYDELNLTEPDRVLGVHADYVRAGAQLIETNTFGANPVKLEPFGLE
PSLHEINVAAARLARQAAGERAAVLGAMGPLGIRIEPWGPTSVDEAADLFGRQVAGLAEG
GVDGFMLETFSDLDELLQAVRAVREVAGEAPIFAQMTFGDAGHTEYGATIEAAAAALEDA
GADVIGLNCSVGPSSMLFGVERMAAATSRPVSALPNAGLPRDIGDRKIYLASPEYMARYA
RRMAAAGARFVGGCCGTSPEHTRLTATLLGTNGPGPARVAVSSPGEADGHAATEPPPLAG
RSALGRRLARGEFVGAVELTPPHGWDPGELLAAAGRLRDVGVHAVHIVDGPAHRSRIAAL
PAAIVIERELGMETVPHYSCRDRNMLGMLSDLLGAAAAGLRNVFLITGDPPRGGPYDTGG
VYDIDSIGLTNVVRQLNLGLDPGGSSIGAPTSFVKGVAANPGAVDPEEEIRRFAWKAEAG
ADFAVTQPIFDPEKFLAFACRIEEFGVPLLVGLWPPLSLENAEFLAHEVPGVDVPLEVVE
RMAAAQAQGAEAAAREGVAMAREVLNAVRSHAAGVLVSTPGNEVDRAAAVLRDP
>A0A3Q7TR34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vulpes vulpes|TrEMBL
MVKEPRGDGGPTPRSEGSSSGSESSKDSSRCSTPGLDPERHERLREKMRRRMESGDRWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRH
IRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFARYLSGEPNQQGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLKGPSPEREAEAL
>A0A1Q8XHF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MHDNEPTGPTAAAGSRGEALSSAETGTARRLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPAGGVTGGGRQGSAHEPEAGRCEAPRVRAVQEQTNPSECVLAHV
LDSSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRAEDVAGELRHA
DDLVRVIREVEADFFGDGRRHVTIAVAAYPATNDHIEAIEVLAAKQAAGADMAITQVFYD
AADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSSLGSASGATL
VERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDAV
DRGYLQATPGRGPSFLRRGSARATVSSHHPVQPLTTITKENA
>A0A2A5S9Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus raffinolactis|TrEMBL
MKITDIYREKNLQKKSVISLEVFPPKTDAGIETIYQTVAGLTHKPDYISVTYGAMGSLGR
ENKTLEIAEKIKKEYGIETMHHLTSINNNPEQITEILAEIKAKNVQNILALRGDLPKNTD
VTGCPDIYHYAHELITDIKKTGDFDIAAAIYPEGHVDSPLDVENIEHVKRKYDAGANFFI
SQLFFDNDKFLRLNDYVKNSGIEAPIAAGIMPVLQTSQLDRMLFFGASLPTRLIKIVNKY
KDSPEDLQKAGMDYACKQIDDLLARGVDGVHIYTMNKPFVANTMMDRYL
>A0A0F0YDE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter kobei|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A3E1UYC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3S0QUH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQG
>A0A1Q9H8R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio panuliri|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKSATGLVAAPHLTCIDASREELIQIADDYWSNGIQSIVALRGD
IPPGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPGWMAKQFE
GLDDDPTTRQLVGASQALDLVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A2X3DNQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyvera cryocrescens|TrEMBL
MSFFHANQREALNQSLAEVGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTYG
ANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDASRDELRAIAQDYWDNGIRHIVALRGDL
PPGSGKPDMYAADLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFNG
LDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A6M7V114|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. NZP2077|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILKETSLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHADGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A1T0ACI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaesserella parasuis|TrEMBL
MSYAKEIDLLNQSVADLNGKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERNRTHSIVKTIQQETGIVAAPHLTGIDATPDELRAIAKDYWDSGIRHIVALRGDEP
TGYAKKPFYASDLVKLLKEVADFEISVAAYPEVHPEAKSAQSDLLYLKQKIDAGASRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMAKMYQGL
DDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGVRPE
>A0A0Q0EXX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. spinaceae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A7U8KG47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella suis bv. 3 str. 686|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATCEDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMVGIRPKTQAAL
EVA
>A0A8B8Z005|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balaenoptera musculus|TrEMBL
MDRPKPKVLPAGHCCPSLGMRAWEAGSARLSVPPSISRSSAMVNEPRGHGGPSPRWEGSS
SGSESSKDSSRCSTPVLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAVDLVKHIRSEFGDYFDVCVAGYPKG
HPDSESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSRLEVPQQIKDVIEPIKDNDAAIRNYGIEQALSLCQELLASGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPSINGKPSSDPVVGW
GPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGDNITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDSCLWQVVEDTFELLNRPPQNKSETEAP
>A0A0G3XKY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceicoccus naphthovorans|TrEMBL
MTDPTPAAAPPAGPPLFADLPGDVKVSFEFFPPKTEKMDTQLWDAVEKLAPLNPSFVSVT
YGAGGSTRERTHATVERIIREAHLPAAAHLTCVEASKAEIRAVAEQYWEAGVRHIVALRG
DPTTEGGKFEPHPEGYASAAELVAGLKEIAPFEISVAAYPETHPEATCPQTDIDNLKRKI
DAGADRAITQFFFAPECFFDFKDKLAAAGITAPVVPGILPVSNVAQTRKFAAMCGAVIPD
WMDRLFEGLDERPGARKLVAATIAAEFCRSLYAGGVRDFHFYTLNRADLSYAICHMLGLR
PNGDKG
>A0A3V8I5F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEIQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J7BI25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSQRVNNFPSRLAERFSTSERVFTVEFPAIDGGNLSAVKSRVDHLLPWFDAANATDSPAA
HAHASNVAIAIALQQCGLEPILQVVCRDKNRIAIQSDIMGAALHGVRNIELLTGDDVTAG
DEPEARRVFDIDSAQAIKIAATLREGRYLSGRKFPDAPDLFIGAVENAAAPPLEYRAERV
SKKVSAGASFFQLQICFHGDRLEKFVSAVNATHPSLPLLPTIVLVKGAKALKFMNGNVAG
IDIPAEIIAQVEQASDPKEAAYQLARAQAEHALSLPGVRGIHFTDFCHDDSLVRLMRDLG
VTPRSIGKS
>R1BLH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emiliania huxleyi|TrEMBL
MSSTDTAGNPTDCRGQLPAVKNGKIIDMVNAWTAATDQPFISFEYFPPKTPEGVVKLHKV
IDEMCKQKPLFVDFTWGAGGSSADLTLELSKTSQQKHNVMVNMHLTCTNQSKEVCDAGLA
GAKEAGICNIVALRGDPPKGQDKWEVTEGGFACALDLVKYMRTNYGDYFSIQVAGYPEGH
PDRITKVSEMSRPLSDREKMRLVDVDGEEFVCTDENYAIELDYLKQKCDAGGDVIITQLF
YDFEVFKAWVQDLRDAGITAPIFPGIMPLNACGGFKRMTGFCKTRIPPAMAKRVAELSGD
DKKAEFAEYGIDYLTDLCKQLVASKLVPGLHFYALNQSERTFQILKRLGYYAPTD
>A0A0A5LFP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia marcescens|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLRDIATDYWNSGIRHIVALRGD
LPPGGGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A1R2SJX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enteritidis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A439HD84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSANPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQSARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPEAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQVVAERLDHILHDEITETQVDMVK
TAH
>A0A7H9VQX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MSIRHQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVF
LGAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHAEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>A0A2H1J9B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MSQEVLASLLKSARYEILPTAGVVDRVHEYVVPGRVITVTASTGLTLEATLSTAEQLQAL
GFTAVPHIAARMVQGRTELEEIVDRLTQAGIDRIFVPAGDATPPAGGYAGALDLIIDLAS
MAAPIQHLGVGAYPETHPLIPDDVTVQAMWDKRDYATHLVSNLCFDPGTIATWLARVRAR
GIDLPLILGIAGKVELAKLARVATKIGVGESTRFLRKNTVTFTKMAKPGGYNPRKFLDKL
APVLDNPTMGVAGLHIYTFNQIKDTEIWRRRQLAALGHSDEVPSTS
>A0A3S3KDG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVCG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A7I0JGP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M4B.F.Ca.ET.169.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVVREFADMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKSAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A6H0CKL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DSM 40868|TrEMBL
MALGTPSTRTDRARTVRDMLASGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSVDWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCDTPVIPEILPVTSVKMLERLPKLSNASF
PDALKERILAAKDDPAAVRSIGIESATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A7W2FRC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio marinisediminis|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKSSTGLIAAPHLTCIDASREELIQIADDYWSNGIESIVALRGD
IPPGGGAPEMYASDLVKLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNQVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPEE
>A0A7K2GUD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4934|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVTAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A820CIX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria magnacalcarata|TrEMBL
MPDNGINIKTICNSSNDSVDLKRSESENGIGTTKGSSPQPVKYVSLAEKIQERISNHERW
FSLEFFPPTTSNAAANLIGCVERMAMAQPLFCDITWRSTGDPAGNKETSSMMIANTMLNY
CNIDTMLHITCCGTKKPQMVQYLNRAKEVGIRNLLALRGDPPVGEQWDPDQTDFRYATDL
VKFIREKFGDYFVICVAGYPQGHPDTESYEEDLGYLKQKVDAGADFIITQLFFQAETFIK
FEADCRAIGITCPIIPGIFPIQGHASFRSVIRLAKLDVPQEMLDSIESMRDNDEAIRDYG
VQACVDLCQKLLDSGKVLGIHFYTLNREYATTEILKTLSFWLEETPLRALPWKKTSQSHT
RSQENVRPIFWSLRPKSYIHRTTDWNEFPNGRWGFSFAPSFGALTDYHLFYMKMDASHDA
LLDEWGHSLTSEEDVWKMFACYISGEKNVLGKSVRHFPWKDEEVSLETNLIQSQLVEYNR
KGILTINSQPPVNGKPSSDPIVGWGVPNGYVYQKAYLEFFTSASNIPALRAVLKNFPNIN
YHFVNKSGEVNETNADGEQATALTWGVFPGKEIIQPTVVDPVSFMIWKDEAFSLWMERWG
KLYEPGSPSYSIIDEVSNTYFLVNLVDNDYPQGSCLWKVLDAMLEYQKSTSQD
>A0A2N2B175|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-7|TrEMBL
MKNNAIKSYIEENILLIDGAMGTFYASQENDYSNSSEKANIHNPEAIKNIHNAYINAGAK
LIRTNTFLANRFDMACTIEEVNEVLKKGFDIATACAKNKDVFVACSIGPITEVSESSDIE
ILQEYFRIIDVFLSLGAKTFIFETFSHTDYIQKFLSYILDKNKNVEVIALFTINSHGYSK
KGIGHKRMVAELNTLEGLTAFGFNCGVGAGHLYNIYKNMDLDQKFYAAVPNAGYPEKIYD
RTLYMDNADYFADKIIDICKLGVKIVGGCCGTTPTHIQRISEQLKNLEIEAYTKRSHKES
RDLVFQKRENPFWDKLDKGEFVIAVEIDPPFGYDISKLMEAAHILKAEGVDILTIADSPL
GKMRLDSLMMSAKIYREVGIDVMPHICCRDKNVIALKSVISAAYVEGIRNYLLVTGDPLP
DILRNEIKSVFNMNSVKLMSLVKEMNEELTNDDVFIYGGALNPKGVNLEKIIEKVCRKKE
AGAKYLLTQPIYTNEDIQRVKEIKERTGIKILGGILPLVSYKNARFINNEFVGMNIPDNV
ISRFRPEMSREVAEEIGIDISVEVGKALKGVVDGLYLMTPFNRATMIGKILNRLR
>A0A5B8LRL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia ginsengisoli|TrEMBL
MLDDNLRASRQTAHDRPDLQISFEFFPPKTDVMEEKFWDTVHRLAPLKPRFVSVTYGAGG
STRERTLRMVRRIKAETGVDAAAHLTCVGASRAEVDDVVRGYREAGINRIVAVRGDPPEG
VGKPFVPHPEGYRNAIELVEGIRRIGDFDISVSAYPERHPQSPDWNNEIDNLKRKIDAGA
TRALTQMFFSNSDYLRYLDRARAAGITAPIVPGIQPIHSFRQIASFAARCGTAIPGWLAE
RFDGLDNDPETHALVAAAVAAEQVTELVDEGVTEFHIYTHNRSPLALALGRILGRRHEVA
AVDAA
>X5EAH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium glyciniphilum AJ 3170|TrEMBL
MVNEIHRPAPASLQVAVADTLKWGTPGRVPFSVEFMPPRNDAAEQRLWSAAEAFHDLGAS
FVSVTYGAGGSSRERTERVASRLAVKPLTTLLHLTLVDHREEELRDILREFASLGLTNLL
ALRGDPPGDPMGDWTPVDGGLNFAHELIELVRSMPECVDFDIGIASFPEGHYRAGSLEDD
TRYTLQKLQAGASYSITQMFFDVDHYLRLRDRLAAADPVHGAKPIIPGLMPITSLKSVRR
QLELSGASLPTDIDELLTRAAAGDEVKNAAGIREAGIEVTSRMAERLIAEGAPDLHFMTM
NNVRATQEVLHNLGMAPAWGPELGQDMVR
>A0A1H5HL66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum sp. MAR_2010_89|TrEMBL
MKVTDHIKKAKDKTLFSFEIVPPQKGQNIQELYNNIDPLMEFKPPFIDVTTSREEHVYIP
KENGLLEQKITRMRPGTVGICASLKYKYDVDAIPHVLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDARKDQQYFKASNGGNTYASDLVGQISDLNKGKYLHEIIETPYKADFCIGVAGY
PEKHLESPSLESDLKRLKEKVDAGADYVVTQMFFDNSKYFNFVKKAKEIGINVPIIPGIK
PLAVKRHLQILPQIFRLDLPQDLVNAVENCNTNKEVRQVGIEWAIQQSKELIKAGVPVVH
YYSMGKSSNIKAIASEVF
>A0A3S0GVC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobiaceae bacterium|TrEMBL
MTDLTIPARADGQDGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHATIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPAG
GIGTPYASHPDGYQSSAELVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAICHLLGIRAK
SAQKAA
>A0A0Q7TJB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Root53|TrEMBL
MSQAPHLPPPVSFEITPARRTEDAPEVERAASALAAAAPSFISVRTGAAGVCQERSLALL
RHVRDTAGARPVGHITGGGLARAELTERIEAHLAAGVRDFLAVRGDAPRAVRARPGIETP
AAIRLLRRIAAAQGLEVTVGVAAHPHGKAGVTDSHGDVAALLAKQAAGAAFALTQVVFDA
ASYACYVARARRAGVTIPVIPGIMPIASPARLRRITALTGVQAPVAQVLELENEQDPRRW
EEIAVARAVRLGRDLLDAGAPALHVYSLNRPETALAVAAGLRGETDAAIREAAIRDPRAA
LVA
>A0A2N7XC56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FW305-122|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARHLATYSPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A2V1ILH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duncaniella muris|TrEMBL
MRVIDHLQANPGRTAFSFEILPPLKGNSIEKVYNIIDKLRDFDPKYINITSHHSEMIFKE
MPDGSFRPQKMRKRPGSVAIASAIQNKYGITAVPHIICKGFTRDETEYALIDLNFLGVHD
LLLLRGDIKGPEKSDDPTKINRHATDLQAQVNDFNRGIYADGETFEPNATPFSYGMACYP
EKHEEAPNMDSDLYYAKQKVDGGADYLVTQMFFDNSKYFDFVERCRKAGITVPIVPGIKP
VVFANQLNVLPRVFRSDIPEAFASELRKCKDDAEVREVGIEWCIGQCRDLIAHGVPSIHF
YTLMASESVRRIAKEIY
>A0A1W9ISM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium HN_bin10|TrEMBL
MSNEPKRLKQVLDQGKFAVTIEYNPPKGTNISAVLESARKLVGRVDGVNVTDNTAAVVRA
GSLPVCRLLYEMGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGRDMAGNKLDGSTAFTIGAAVTPEADPIGPMLAKFEVKV
KAGAQFFQTQAVYNPEQFAAFMKAVRSFKVKVLAGILVLRNAKMAEFMNANIPGVSVPQA
MIEELKAAGDKAEDAGVDIAVRTIKAVRSHCDGVHIMAIKATHRLGDIITRAEIG
>A0A1K1NTF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. YE71|TrEMBL
MKTADIFNRKKVFSLEIFPPKPSADESVIYDTLDKLTDIEPDFISVTYGAGGGKNGSKTI
SIASDIVSKYSTTSVAHLPCIDLTKDEAAEILDSITENGIENVLALRGDIPEGAEVKGDF
RHADELVTFIRENYDLNIVGACYPEVHPESRNAVDDIRHLKHKVECGVDHLITQLFLDNR
HFYDFREKTQLAGINIPIEAGIMPVTNKRQIERMVKLCGVELPKKFVKVLDRYGDDRLAL
RDAGIAYAVDQINDLAAEGVDGIHLYTMNDPFIAHRIFDAVHNLI
>A0A1E8ZBA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC074A09|TrEMBL
MSPRLSASAPLDQISEDTPKELKRTALSFEVIPPRHDADAAKIDRLLATLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTEEELVGWIDTLVDAGVRGLLALR
GDLPEGGMPEGHLPHADSLVRLIRRWESDRVARLAAGRLAVGVACYPNGHAESATPDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTKVLDQLAAATSPEEEKEIGMQITASLAKSVMNAGADGLHIYTHNNPDITTDLL
HRIGAIP
>A0A6L4AJ99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKAGSNLEKVLAAGHFAVTAECGPPRGADPEVVRKKAAYVKGNVDACNVTDNQTSVVRMS
SVAGCMLLKELGIEPLLQMVVRDRNRIALQSDLLGASALGVRNMLCLSGDHQKFGDDPQA
KNVFDIDSMQLIHLVKTMRDEGTFPSGQKLEGAPKFFIGCAVNPFADPFEIRVPRLKLKM
MAGADFVQTQCIYNMEKFKAYLEEARRQGLHEKVKILAGVTPLKSAGMAKFMKKMVAGMD
IPDPVIKRIADEPKEKQAAKGIEMCIEQIQELKEMEGIAGVHVMAIEWEEKLQEIIGGAG
LLPRPVVE
>A0A5C1NBF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. Y2R2|TrEMBL
MNDVNRAALTAAFVPPARTAVRFELLPITGMQEAARALPEGAEVTVTCSPRHGLERTLEA
AEWLVEAGLQLQVVPHIAARLVRDHAHLERLLQRLETLGIDDVFVVGGDAPRPVGSYPHG
LALLEDMNRLSLRPTRVGVPAYPEGHHHIDASRLQQDLEAKVALANYAVTQLCFEARPLL
HWREWQKQLGLELPVHAGIPGVIERKRLLSIALRLGIGPSVRSLRSKSGRMSRLLGGSAY
HPDTLMEALGPSLGDSDGGFAGLHVYTFNHVAPTRAWLESLKDPRLSQYEDGQGDRR
>A0A1G0K6Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPLOWO2_02_FULL_61_13|TrEMBL
MPANKYSFEFFPPRTEEAASRLRETWSCLALLGPDFFSVTYGAGGGTRERTLETALAIQH
GTGIEGVPHISCTGADIAELETTLERYRSAGVRHVVALRGDLPSGSIGRGSLQHASELVQ
LIRHTTGDWFHIEVACYPEFHPQAKSPAADLANFQRKVDAGANSALTQYFYNPDAYFRFL
DSCGGLGIKVPIVPGVMPIINSTQLIRFSEACGAEIPRWIMKRLQEFGDDVQAIRAFGVD
VTTALCERLLAGGAPGLHLYTMNRSEAAERIWRNLDLPRR
>J2XIF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM84|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAVCNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEAKVPAAPHLSCVGDSKDELRALLTQYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQARNFEVDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQADASLAIWNNLKLPR
>X0NTS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. vasinfectum 25433|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDDVKGDDERVKMVGVDIVSELIDKIKTIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A1I5YH87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parafilimonas terrae|TrEMBL
MKITEHISNAKDTLISFEILPPLKGKSINSIYDHLDPLMEFKPSWINVTYHRSETAFKKK
ADGNFEKVEVRKRPGTVGICAAIMNYYKIDAVPHIICGGFSKRETEDALIDLNFLGIDNV
LVLRGDADKNSASFEPEPDGNPYAIDLLKQVVNLNSGIYLDDDIRDGGKTKFCIGVAGYP
EKHFESPNQQIDMQRLKEKVCNGAEFIMTQMFFDNQKFFDFVKKCRDNDINIPIIPGLKP
ITSRKQLSVLPRIFHVDIPAELSEEIMRCKTDEDSEKVGTEWLVQQSRELKKFGVPVLHY
YTLGKPRVIQNVMKKLV
>A0A1G0K8Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPLOWO2_02_FULL_61_13|TrEMBL
MSAGERDVQDPTRALKPGHSSAGHLEALLRSGEFAVTAELSPPDSSDPEEVFRRARFFDG
CVDAINATDGSGANCHMSSVAVCALLTRLGYSTVMQVSCRDRNRIAIQGDVLGGAAMGVA
NVLCLTGDGVQAGDHPQAMPVFDLESISLLQLLRGMRDEARFQSGRKLMLPPRVFLGAAE
NPFAPPLEYRPQRLAKKIAAGAQFIQTQYCYDIERLKTFMTVARDLGLPGCAFILVGVGP
LASARAAEWIRTHVPGVYIPDAVIARLAGSQDQKREGRQICIEIIQHIREIEGVSGIHVM
AYRQEEAVAEIIQQSNVLRGRVPWYPGLDAARAGTED
>A0A3N5ES14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MEAANQPYTGHRSDSTYSLAAELDPPKGTHLDGFLATALSIRGRIDTIRVTDSEHAIMRM
APVAPCLALKDKGIEPVMIINGRDRNRISFQADLLSAWALGIRSIVIREGHDPAEGDQPV
VRSSGDLDMLTMLKCVAALNDGRDLGGEPLDGAPAFTVGATLELFDDASRNREQAELLKQ
MAAFGVSSVTLGPTYDLNIIEQYLPAAEQAGIKLHASIMFLRSITMIRYLNNLKGVPSIP
QEFLKKMMQAPVKQDAGLSIGADFVGEISGLVDGIVLLALGWRERLPEFLTLIGR
>A0A238X1B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halorubrum vacuolatum|TrEMBL
MATGTSAATDVHGVQTLLTSARFELMPFKSFDEEIEHLPENATIAITTSPQLGIERTVEK
TELAKELGYDVVPHIAARYVEDTDQLEEIAERLEAAGVTDIFVPGGDREEPAGEFESAYD
MLVALEDLPYSFPEVGITGYPEGHAFIDDEELAASMERKAPYATYIVTQLCYDPNTVLEW
IETIRDRGIDLPVEIGIPGVMNYQRLLQISQKVGVGDSVKFLRKTTGILGFVKQLVGSRG
RYKPDDLIDGLSPHVGDETYNIRGVHIYTFNQTPDTESWRRGRLA
>A0A7T4E5Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter deleyi|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLRDILQTYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAASVSADMDHFVAKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHSQLLRFSEMCGAEVPRWIRLRLAELGDDKASIRAF
GVDVITELCQNLLDNGAPGLHFYTLNHAEAPLAVWKELSV
>S2XN98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenisporosarcina sp. HGH0030|TrEMBL
MSFLEKLKNQILIGDGAMGTLLYSYGTDCCFEELNLSHPEQIQNVHKAYIGAGADVIQTN
TYAANYLKLQRYGLEDSVKEINSAAVHNAKIAAKNDAYVFGTIGGNRGVKPNSISLEDLK
RSFREQLYCLLLEGVDGILLETFYDLQELEAVLTITRKETNLPIISQLALQEPGILQDQT
PVNEAFLRLENLGADVIGLNCRLGPHHTLLSLEQIEIPAHAFLSAYPNASLPAYTDGKFH
YEGDAEYFRKSALAFRNEGVGLLGGCCGTTPEHIRAIASELKNVVPITQKDVKIRPPKQV
VEVISIKRDFPPLEKIVKKKPSIIVELDPPRKLDTTKFFMGAKALKEVGIDAITLADNSL
ASVRISNESLGYLVKTQLAMRPLIHIACRDRNLIGLQSHLMGLHTLGMNDVLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTAFSIAAAFNPNVRYLDKAVQ
RLEKKVQLGADYFISQPVFSEEKLLEIYESTKHLNAPIYIGLMPLLSSKNAEFLHNEVPG
IKISKTIRDRMAKFNDNPVQAVQEGIEITKSLIDTALDLFNGIYLITPFLRYELTVELAL
YARQRASEVQRNKIAVSTIH
>A0A285RVY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ureibacillus xyleni|TrEMBL
MGLLEALNSKVLTADGAMGTLLYSYGLDHCHEEMNIVKPELIEKIHSEYILAGADVIQTN
TYGANAIKLARYGLESKVVEINEAAAKLAKNAASTGNQFVVGSIGGIRGVRKSEVTLDEI
LDAIREQAQTLIRADLDGLLLETYFDFEELTETLKMLRNMTDLPIIAQVSMHEPGVLQNG
LKLNDALQQLEALGADVVGVNCRLGPHHTIQALEGVELPKKAFLSAYPNASLLDIEEGRV
IYESETDYFARAAVQLRNQGVRLIGGCCGTTPKHIEAVKKQLELLKPLTEKQPVQQRDVY
IQDAEPTRLEPLHEKVKRERSVIVELDTPRHLEIDAFVDGAKALYNEGADIIMMADNSLA
SPRISNVAMGSILKLQHGIRVMPHLTCRDRNLIGLQSHLMGLNALGLHDILAVTGDPTKI
GDFPGATSVYDVSSMELISLIKQLNEGISFSGKALRKKANFSVAAAFNPNVRVLDRAVSR
LEKKIEHGADYFISQPVYSSEKIVEIYEATKHIEAPIYIGIMTLTSFRSAEFLHHEVPGI
KLSDEVLARMKACEGDKEREAQEGVAIAKELLDTATKYFNGIYLITPFLRYDLTLQLMQY
IKQLDEQNEGVEANV
>A0A8H5W0I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium tjaetaba|TrEMBL
MHIKDMLSDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIGESRGSKTDSEIMLTMVVNNDFHDNKTIFELLKG
LEVKDLTTPATPLTESVGNGAVDTEPIANGTAATAVAN
>A0A671QEY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus anshuiensis|TrEMBL
VKRPLSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHWFSLEFF
PPRTASGAVNLISRFDRMGSGGPLFIDVTWHPSGDPGSDKETSSMMIASTAVNYCGLESV
LHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLVKHIRCE
FDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAETFLRFVKDCRA
IGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGIQQAVEM
CKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKVEDVRPI
FWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEEL
MNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDALAPETNLLKDELEKVNRRGILTINSQ
PNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVQG
KNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWVKLYEDESPS
RMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFALLDSPRATQEEGSQS
>A0A1E5IFW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endomicrobium trichonymphae|TrEMBL
MKFREKLKSDKFLITAELFPPKGVEISSFLRRADCLYGLDAVNVTDNQRASMRVSSLAMS
RILIERAIEPILQLTTRDRNRISLQSELLGANVLGIENVLLLSGDHPSIGEYSSAKAVYD
LDTLQLIKTARLLETGMDLAGKKLQGSPKFCVGAVVNPSVRSVDLQALMLEKKVKAGTEF
FQTQAIFDVQTYKNFFDKVKYLKVKILPGMILIKSPKFLQFLQSMSGISIPDEIKDRINS
ASDPLAEGIKICSETIKKLRSFADGVHIMAIGTEEHIPEMIRDSL
>A0A4S4NJ32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lewinella litorea|TrEMBL
MRVTEHFERANGQTLLSFEVLPPLKGGSMQAIFDTLDPLMEFEPPFIDVTYHREEYVYKK
RPSGYYEKTAIRKRPGTVGICAAIMHRYGVDAVPHLLCGGFTKQDTENALIDLAFLDVQN
VLALRGDARKFEGKFVPEKEGHHYACELVGQIVDMNNGHYLDELIKDEHASKTNFCIGVA
GYPEKHFEAANLEHDLRYVKSKVEAGADYIVTQMFFDNQKYFDYVDACRKVGINVPIVPG
LKPITKLYQLNALPRMFHIDLPDDLVTAMTKAKDAEARVQVGIEWCTAQSKELKERGVPC
LHYYTMGDSSTIKAIAEQVA
>A0A447UP51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter koseri|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVSLTERGCRF
>A0A367YS05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desertihabitans brevis|TrEMBL
MPATPRPAARTPRQQPVADLLATADCPLTSFELFPWRSPEEERVFWQTTRELEALGPDFV
SVTYGASGSTRDRTVGATEAIASHTTLNTMAHLTCASQSRDELRRTIGAYAGVGIRNVLA
IRGDMPGGPTVPFEQHPDGLANATELVRMVRELGDFCVGVAAFPDLHPQAHDADLDARVL
VQKAEAGASFAITQLFFTFERYVDLVQRVRALGCDLPIIPGIMPVTRLTQISRMAELSGA
DLPDWVVRRLSEDESPATVRQVGIDIATELCERLLEHGVPGLHFITMNRSTATREIFGRV
LGTGSAARTPAS
>A0A6N7AM36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSFKDILNSGKFAVTAEVGPPKGTDIKEMIHHMELLKGKLDAVNVTDNQSAVMRICSLAV
CKVAMEHGLEPILQMTCRDRNRIGLQSDLLGASILGIKNVLCMTGDHVSAGDHKGAKPVY
DIESVQLLKAVDGLNKGKDISGNDLKGSTDFFQGAVVTPEANPLEPQLMKFDKKVRAGAN
FFQTQAIYDIEKFREFMKHARKFPVKILAGFVVLKSVGMANFLNNNVPGIRVPQALIDEL
KAAGKEKALDTGMNITARHIKQLKDEKICDGVHIMAIGMEDKVPMIMERAGLL
>A0A7C1FJZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MGFRESLDSGKFLITAEIGPIKGTEIDGLLEDARLIKEKVDAINVTDLQSSVMRLGSMAV
CHLLKDLGVDPILQMTCRDRNRLALQSDLLSAWVLGIRNVLVLTGDHPTLGDHPQAMPVF
DLDSVSLLKVIGRLNEGFDMAGNQLKGAPNFFPGAVVNPGANTETALEMQIIKMEKKIEA
GARFFQTQGIFDLDLFERFMKRIEGFKTKVLGGIILLKSAGMARFMNKNVAGVFVPETLI
KEMETTKDKVKTSVEIAARLIKGLKDLCQGVHIMAIGWEKRIPMLLEETGL
>A0A6J4PZZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Rubrobacteraceae bacterium|TrEMBL
MTDSEILSRPRFEILPTEGAEERAGHLPRDGKVAVTCSPGKGIENTLRFSERLLQRGFRV
VPHIAARLVGGRAHLEEILRWFDEHGLREIYVIGGDSKEPVGPYASALELLDAMSRLEHG
VEEVGIGGYPEGHPLIDDEELDRALLDKQPFASYVVTQLCFDADTILRWISGIRHKGIRL
PVYVGLPGAVDPKKLLRVSLKVGVGDSVRFLKKQTGLVGMLLKPGGYSPDELVERLAPYA
GDEHYDIVGLHLYTFNQVESTVQWRQRMLGPQKTSGTGAPR
>A0A662RLK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon|TrEMBL
MGDEVYSDLMKELVEGKYVFTGELEPEKAGDVHEPIEMARDLKGLVVACNVTDNPQSFAY
VNSMAASYLIQKETGMECVYQLRCADRNRMALLSDVLGAGALGLKNILALTGDHVSLGDT
PNAKPVFDLDSTTLIAMIRKVVDEGKDLEGNEIHNPPKLHVGGAAAPGAANLKAEVAKVK
RKIKVGAEYIQTQVVYYTEVLDRFFKELGKVDVPVLVGIFPARTFGQADFFDKYVAGVDV
PPDYLEAMRKTKEIKDKEKRKEEVDRVNVEFFTAFLEHLKDTPAAGCHMMAVGYPRIIAP
LKKVIE
>A0A7X8HV07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epulopiscium sp|TrEMBL
MKISKLFKTKTVYSFEIFPPKKTSPIDTIYTTLDELKGLSPDFISVTYGAGGSSNKDATI
EIASAIKNKYNLESVAHLPCIYLTKENVYEMLKEFNNKSIENILALRGDINPDIPPKKDF
KYASDLISFIKENGNFNTIAACYPEGHTESKSLKEDIKNLKYKVDSGANHLITQLFFDNN
CFYYFLELVRKEGIDVPIQAGIMPVTNKNQIDRIVKLSGATLPKKFTAMLDKYENKDLEL
KEAGIEYAIEQILDLISQGVDGIHLYTMNNPYVAKKVTEAISSKI
>A0A5C5RT85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tsukamurella sputi|TrEMBL
MTEQSRTVLDRLDAVRASGRMPFSVEFMPPRDADGEARLWRAVRTFERMDPAFVSMTYGA
GGSTRDRTVRVTGEIAASTTLLPVAHLTAVNHSISELRALMGAYADQDVRNVLVLRGDPP
GDPLGRWVRHPQGLKYACEVVELVRELGDFHVGVASFPEGHHRSPNRESDIRYFANKLRA
GADYSITQMFFDVDDYLRLRDDVAAFDPEQGAKPLIPGIMPITSLKSVSRMAELSNAKIP
DAMRNELRAAAGDGPEEDRAAVRAVGIEIATRMGERLIAEGAPALHFCTLNFAKATSEVL
ENLGMLPVGV
>W7HYD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drechslerella stenobrocha 248|TrEMBL
MQIKITDKIKALPKEAAYFSLEFFPPKTPAGLQNLHARLERMSKGLRPLFVNVTWGAGGS
TASKTLELAHICLTVGLTTVLHLTCTNMSRAVLDDALDNAKLMGIRSILALRGDEPRQRE
YFGHQQQGVEGGSSNEFTHAVDLVRYIRQRHGDFFAIGVAAYPEGYTESAYPVEQSPALD
LPYLREKTAAGADFIMTQFFYDVGAYLAFEKLLRDDPSGVFKTIPIIPGLMPIQSHQIFR
RTTKLCSVKVPSEISDAIDAVKADDEAVKELGIRIVTDMIERIKATRETAGGLARGFHFY
TLNLEKAVAFIVERCGLIPELPTTSFAAIAPIDEIAVMDDEGPGLLSVNGGSSAALEARR
RNRRASSIISDPHNRVIVDTVSSARSDLQAEAGEAGLPKILDTGSQEGNLAISEGEGALG
REATWDDFPNGRWGDARSPAFGEIDGYGVSLHRTPTESLRLWGHPTSVADISNLFVRNAK
GELAAMPWSEEDSLNPESKLITDYLATMNARGWWTVASQPAVNSARSDDPTFGWGPRNGF
VFQKAFVEFFIPKEEWEGLKPMLDYGGDDVSFYAGNKAGEFETSMPSDTATNAVTWGAFP
GKEIVTPTIIEEVSFKAWRDEAFDIWGEWQRIYPPSSPTAKLLGEMKERLWLVTDKDALW
KGVLGL
>A0A2C6J1F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasaccharibacter apium|TrEMBL
MAEVSFEFFPAKTDEKAAALLRVAQRLAAYEPRFMSVTYGAGGSSRERTLEALRQMVEAL
PIPLAGHLTCVNAAKGEVDDVARAYWDLGVKHIVALRGDAPVAKGEAPTPYRPHPEGYHY
AADLVAGLKKIAPFEISVAAYPETHPEAQSAQSDIEHLKEKFDAGADRAITQFFFDPECF
LRFRDRAVKAGINKPIVPGILPIGKAVQAWRFAKMCGASVPEELKTLFEGVDDLPPIRTR
LSAVVVDRLCQRLRAEGVEHFHFYTLNQSAPTSTLCTLLGRQRSHPLVELAS
>A0A427X392|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. FDAARGOS_559|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A354YSS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas wolfei|TrEMBL
MRIIELYRQKVPLLSLEIFPPRMAYPLESVFDTVQELKKLNPAYISVTYGAGGSNRERTV
EIAARVKKEYGIEAQAHLTCIGHRQEDIKNILARLNREGICNIMALRGDIPEDEPEFDSS
RQEYHYAFELIRDIRAAYGDSFGIAAAAHPEGHPECPRLKDDIFHLKNKADNGVDFLITQ
LFFDNRIFFDFWERCQATGINCPVIPGIMPVLNAGQIKRMIYLCGASMPARLLKLVDKYE
KEPADMEKAGIDYASQQIKELLENAVAGVHLYSMNKPRQISEIVYNIGLAYPGKD
>A0A1H0JK33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas arcis|TrEMBL
MSSQEHPLGISFEFFPPGTDAGREKLIHVRDELAARNPRFFSVTYGAGGSTQARTREIVR
KVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRHETGDHFDIAVAAYPESHPQAPNLDRDVENFARKMNAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKIVDNLTD
>A0A0R2CHY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructilactobacillus florum DSM 22689 = JCM 16035|TrEMBL
MNVSILQQQLNPAGRFALPVGFSPKNLIIEEQIVMAEHQPSFSLELTPLGENSEQQALLQ
SLPSWGALQPDFISITAHGGVERSYGADFELATAVQQDLQIPALVHIAGQTWSPTTLKPY
LEKLRAAELRHVLTIRGDEVFKNAEQQNFTTAANLAAFIRQVGGFDISGACYPHLYHMPP
TELPDDLHLLQAKLSSGMTRLITQLFFDNEVFFAWQRRVRSIGIGVPILAGIFPVTSLQQ
KSRLKQLAGGSLPDQLNDQLAGVANDPAAVQAVGIDYAVNQIKDLLARGVDGIHLYTMNN
LEVTQKIYQKTQAWFNKSK
>A0A5N8YBV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium AC-647-N09_OGT_505m|TrEMBL
MKFAELYKSGRPDISFELFPPRTDRTMAELEERLPKLIALDPSLITVTYGALGTTQSRTM
EITSKIMNQYGMESAHHLTCVGSSREEIGLILEDIRKHNIKNIVALRGDPPRGETEFTSP
KDGYNHGNELVEHISRVGGFSIAVAGYPEKHVEAPDFKTDIQNLKRKVDSGADVVITQLY
YDNRNFYDFVERCRAKGIHQPIIPGLMPILGMEQIKRITSMCGATIPRGLLRQLEDAGED
EELVHEISIIHTANQALDLLSQGVPGIHFYVLNRHSHIAEIMERIEPALRRIKGNVPAE
>A0A1V5CDU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdaceae bacterium PtaU1.Bin034|TrEMBL
MMIESRLKKVLNGGTFAVTAECGPPKGADPEVIRKKGSLLKGYVDSVNVTDNQTGVVRLS
SLASCAILREEGLDPVLQMVTRDRNRIALQSDVLGASALGIRNILCLSGDHQTLGNQPAA
KGVFDLDSMQLLQVVRQMRDKGIVLGGDQLSSMPELFIGAVENPFGDPRNYRVARLAKKV
RAGAEFIQTQCIYNLPAFKEFMKEVCDKGLDEKVFILGGITPIKSARMAEYMKNNVAGMD
VPEEVIARVKAVPAKEQRQEGIKIAVETIQALKEIKGVHGVHIMAIEWEEAVPELVEKAG
LFPRPAV
>A7HVS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)|TrEMBL
MGKPEKKEQRERTRVSFEFFPPKTPEMEETLWRSIRRLEPLQPEFVSVTYGAGGSTRERT
HATVKRILDETTLEPVAHLTCVGASRAEVDDVIRAYWDAGIRHIVALRGDMPELGAPYQP
HPDGYQSTPELIAAIRKIGDFNVIVSAYPEKHPESVSLEADIELLKRKVDAGATRAITQF
VFDTEKHVRFLEKATKAGIDVPIVPGIMPTTNFKGTKRMAERCGASIPQWLESYYAGLDD
ELETRKLIAAYVAAEQVNRLRAYGFDRFHFYTLNQADLTFAICHVLGLRPQAALTPAEPA
>A0A0Q4CCD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. Leaf2|TrEMBL
MTATTRPSEAPLFAGLPGDIAVSFEFFPPKSEKMETQLWDAITQLAPLDPAFVSVTYGAG
GSTRERTHATVSRIVRETDLVPAAHLTCVAASKAEIADVADQYWDAGVRHIVALRGDPPP
ADGGRFVPHPQGYASAADLVAGLKAQHDFEISVAAYPEIHPEATSSAADLDNLKRKIDAG
ATRAISQFFFSTEAYFRFLDKALAAGITAPILPGIMPVTSFAAIRRMSGNTLVPAWLETM
FQGLDERPGPRALVAAVAAADLCKRLYEGGVRDFHFYTLNRAEQAYAICQLLGLRPKENA
A
>A0A4Q0HY06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas azotoformans|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFSPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A6B2QXL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orrella amnicola|TrEMBL
MTSSTRPAFSLEFFPPRDAAAQARLVDGARQMSVINPHYVSVTFGAGGTTREGTLDTVRT
MRGMGWDAAPHLSCIGSSREDLRALLQTYRDEGVRRIVALRGDMPSGMGIESAGALRHAS
DLVELIRAETGDWFHIEVAAYPEMHPQASGPEKDLQHFVQKVRAGANSAITQYFFNADAY
FDFVDRVQSQGIDIPIIPGIMPITNYTQLMRFSEMCGAEVPRWVRLRLAEMGDDRESIRA
FGTEVVTDLCQTLLDNDVPGLHFYTLNNAEATLAIWKGLSN
>A0A2W6DZ57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MTAVIDRLGGDRPVFSVEFFPPRDDAGERQLWQALRDFEPLDPAFASVTYGAGGASRDRT
LRITGRITQQTTLVAMAHLTAVNHSVAELGQVIGNYAEAGIRNVLALRGDPPGDPLGEWV
AHPQGVHYAEDLVRLARSLGDFCVGVAAFPECHPRSSDAESDVRYLVAKLRAGAQFAVTQ
MFFRPEDYLRLRDQVAAAGADMATVPILAGIMPITTLRGVQKMADLSGCTIPVAVRDRLA
AVGDDPAAVRQVGVDVASELCERLLTEGVPGLHFYTLNRSGSTRAVLARLGMAPGRPAAV
AAH
>A0A1E7GHW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium S5133MH15|TrEMBL
MSFQKRLSANEFVVLAEMHTPKGVNISRLVNDARRMKGRIDAIVVPDMDNGIMRMSALAG
GVLMQQQGVEAIIHVYCRDRNRMALQGDMLAAYVLGVQNLLVTHSEDIEQSDHRDARQVY
DLDEVELVQVIATLNQGKDMGGFELDGVPEFTAGCTIAPYSDEKGLAGELEAAAKKIEAG
AGYIITPPVFDLDSFAGFMEKAKELNAPIIPTVFLLKSLAIAQYIARSEPGANISEDLIK
RIRKSSDRELEGIKIAGETVAALKDLSQGVMLQTLGWEHKLPEILDMAGL
>A0A1E7GKN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium S5133MH15|TrEMBL
MSSFKKSLDSGKFIVTCEVAPPKGINLEKTAHHIDLLKDKVDAMNLTDHQSSVMRYPSLG
GALMVKEMGGEPILQMTCRDRNRLALQGDLLFAASRGINNVLCLTGDSVMLGDHKTAKGV
FDLDSSQLLAAIRILEKGKDLGGNDLDGSPVFCAGAIVTPEANPIEPQLIKFEKKIEAGA
EFIQTQAVYDLVRLKTFMEYARQFPVKILAGILLLTSAPMARFMNKNIAGVNVPQTLIDE
ISQAPKGGAIVKGIEIAGRMIRTIHTEKICDGVHIMAIGKEELVPDIMAAADLTS
>A0A662PT54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MKTNSKLEKILESGKFAVTAEIGPPKSADAEVIKRKARALKGYIDAFNVTDGQTAVVRMA
SWAACLIGKEEGLDPIVQMTCRDRNRIALQMDILGIAALGINNILCLTGDYVSMGNHPSA
KPVYDLDSIQLIKTVKEMRDDKKFQCGEEMDVEPRLYIGAVANPFAGFPLELEVLRLEKK
VKAGADFIQTQCIYNIEKFERWMELVRERKLHEKVHILAGVTPLKSYRMARYMRENVPGI
DIPDEVLERMKNAPKGEA
>A0A3B5KZ85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xiphophorus couchianus|TrEMBL
MVNQVQQVDGSWQSCRGDSSGASNSSAESSKESSRCSTPLPDADRSDRLREKMRKRMDSG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGDDWEDEEGGFNFAV
DLVKHIRSEFDEYFDICVAGYPTGHPEAESYEQDLRHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAAGITCPILPGIFPIQGYQSLRQLVKMSKLEVPEEITKIIEPIKDNDAAIRN
YGIHQAVDMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWVEDPRRPLPWAVSANPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKNEQSVFEVFTCYITAQPNRNGQKVLCLPWNDEPLAPETNFLKDELEKVNR
RGVLTINSQPNINGKPSADPVVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVDVHGHNMTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWRVIDDMFELLDATPEPLNDEAAS
Q
>A0A417T6Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. OM04-5BH|TrEMBL
MSELLNILREHKIIADGAFGTYFQSKYGDNDNVAPERANLTDRSKVVAIHKDYIAAGARL
IRTNTFASNTISLGMNFMEVLANVRNAVAAARTAVRESFVRDKVFIAGDIGPIPKDSGAD
HSQIVNEYMTIADIFIEEKLDMILFETQAELSDILPVIHHIKEVSDMPVWVQFSVNQFGY
SNAGLSARKLWELAAADDDIDGIGLNCGIGPAHMEKILKTVNLDCGKFVSVLPNAGYPKL
FMNRLTFSNNIGYFSEKAGVFARMGADIIGGCCGTDPANIEDIRRTVSLQHNDKIKTVAG
QTHEAFDPCDTGLLSVRKNDPTHKIIAVELVPPVNADDEKLLDAANILKNAGADVVTFPD
SPSGRTRADAVLMAEKVKNETGLRVMPHICCRDKNAIAIRATILGARLNGIEDFLVITGD
PVPVMIRQTTKSVFNFDSIGMMNIISDMNEEILKSHRVSYGGAINHNRVNLNIEIERVKK
KMKAGATFFLSQPVFSARQAEILKGIKEQTGAVILVGIMPLVSRRNAMFMKSEMSGINIP
DEVINRYPEDGSREEGEAVGVALAKDIMAATEDFADGYYFSFPFNRVGMLKKIME
>A0A8B5X3M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MHIARVFEQYRPAFSFEFFPPKTPAGSERLFRTVEELVELAPNAVSVTYGAGGSTKNLTH
ELVARIRAETSLTVVSHLTCVGASRDETAQILDKYASAGIENIMALRGDPPGGGPAPGAR
KPAAVAETPIEGEFPYAADLVAFIKNRYPEMGIGVAGFPEGHPATPNRLIEIDHLKAKVD
AGADYICTQMFFDNRDFLDFRERCELAGINVPIVAGIMPITSRSGMARMAELAAGSRFPA
RLLKAVERAETDEYVENVGVHWATEQVMELIDADVAGVHFYTLNKSDATRRIYEYLGVTD
SRRLAAVPS
>A0A6V1V0A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heterosigma akashiwo|TrEMBL
MVEGKKISLMAEERAREGKPFVSLEFFPPKTAKGVENLVERIQRMKSIDPLFVDFTWGAG
GSTSELTLDLSLKAQQEIGVQANMHLTCTNMEAAKVDAALEGCKRGGIRNILALRGDPPE
GQEAWEATEGGFACALDLVKHIRKEHGDYFDIAVAGYPEGHPTKITLAKGGYYALSEAER
GRCRIDEKGDVWVCTDADFEGELAYLQAKVDAGASAVVTQMFFDAQVFLDFVAACRARGI
TVPILPGVICIEKYAGFVKMAEFCRSRVPEALRMSLYRVKDDERAVKRVGIQWGADLCRR
LLAAGTPGLHFYTLNMEHVCAGILEELGLAGEFCRKPAAKIASLLARSRDWLSFEYFPPR
TAEGLANLEKRFQKMKAYRPLFADITWGAGGSSADVTLGLAKKMQVDHGLVTNMHLTCTN
MPEALVHDALRACRRTGVRNIVALRGDPPEGQEAWEATEGGFSCALDLVRYIRATYGDFF
GISVAGYPEGHPSKIKEVPGGLAALSPSERRRCRVARGGDGEETVLVCSDDHFRGEMAYL
KAKVDAGADFIITQMFFDPEVYIDFVAECRKYGINCPVVPGIMCVNNYGGTRKMTDMCKT
RVPQQVWDALEPIKNDVAALKAWGVEFGERMSRRLMEGGAPGLHYYTLNLDKVTLGIVDA
LGKGPSALAEGPSKQAAVPPPAPAAVLA
>D5XEF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermincola potens (strain JR)|TrEMBL
MKAGSRLEKVLNAGHFAVTGEINPPQNAEGKVIAHHGEMLRDYCDAINLADNQTAVVRLS
SIASGIVLQQMGIEPNIHIVARDRNRIAIQSDVLGAAAFGIKNVLCLSGDHQTLGNHPTA
KNVYDIDSIQMLKMLDGMRKGYFANGEEIKGPRPELFLGCAANPFGDLFEYRVLRLAKKI
EAGADFVQTQSIFDMERFERWMEIVRAAGLHKKVKILAGVTPLKSWKAADFIKNKVAGMI
VDDRLIERLKAAKDPQEEGIKICVEQINYLKTMEGIAGVHIMAVAWEEIIPEIVKRANLY
PRPQIN
>F2F7E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solibacillus silvestris (strain StLB046)|TrEMBL
MGLLEELQTRVLTADGAIGTLLYSYGLDYCHEEMNIARPDIIEKIHSEYIAAGADIIQTN
TYGANRIKLARYGYENRVKEFNEAALKIAKRAASLDGQYVLATIGGIRGIRKSDATLDEI
LAAFQEQAEVLLAGEPDGFLLETYYDFEELSHCVHLLRSMTDLPIIAQVTMQEPGVLQNL
MTLNEAFQDLERLGADIVGSNCRLGPFHTIQAFEGVNLPNKAFLSAYPNASLLDIEDGRV
VYESETDYFARAAVELVNQGVRLIGGCCGTTPKHIAAVKKRLANMQPIETKEEKHRSTQF
VRIPEPRKQEPLHEKAKRERSVIVELDTPRHLEIDGFVEGAKQLSKAGADVIMMADNSLA
SPRISNIAMAAILKEQGIRSLPHLTCRDRNLIGLQSHLMGLDALELHDILVVTGDPTKVG
DFPGATSVYDVSSMELISLIKQLNKGGSFTGKSLRKQANFSVAAAFNPNVRVLDRAVARL
EKKIEHGADYFISQPVYTKEKIIEIYEATKHLETPIYIGIMPLTSSRSAEFLHHEVPGIK
LSDEVLARMAACGDDKEASTAEGIAIAKELLDTACEYFNGIYLITPFLRYDMTLELMDYV
KQYDVESKGVQSNV
>A0A1Q6EMU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. 56_sp_Nov_56_25|TrEMBL
MNVVEIINEAIASGRTRFAFELLPPLKGDGMQKIFAAVEPLMALDPAYVNITFHREGIKE
TEREDGSVEWHVVRRRPGTVGISAAIQNRYGVEVVPHLICGGLSKYDIEDTLIDMDFLGL
HNVLALRGDKSQNEKRFMPHPQGHAHAVDLVRQIADMNRGKFIDGEVEECHHSKFSIGVA
GYPEVHAEARDITSDIARLRDKVDAGAEYVITQMFFDNAKYFDFVRRCREAGITVPIIPG
IKPLSTLRHLEILPETFGVKLPEELVREVKAHPDGVREVGTEWAIAQSRELMAAGVPVLH
YYTMSRTTNIQKIVKAVF
>A0A318FH83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella oxytoca|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRTIAQDYWDSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1Y4V6G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. An11|TrEMBL
MKHSSIFQSDSNISFEIFPPKKWESFPNLYETLDALKELHPSFISCTYGAGGSNSKKTAE
IVSYIQNTLGIEGIAHLTCAALTEESFLSTIRTFQQKGIHNVLALRGDKPADMTDEAFQS
RVYQHPSELIPALKDAGFTVAAACYPEKHFESADMGEDLFFLKHKVGQGADFLISQLFFD
NDIFYRFLEMCEKAGIHVPVEAGIMPITSAKMIGTTINLSGASIPKSMSDLLARYQDSPD
DMRKAGIDYAIRQIQDLQSHDADGIHIYTMNHADVAKEICKAL
>A0A4S8PLQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium rosettiformans W3|TrEMBL
MAQIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKVF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGFHEKCFILVGV
GPLASAKTAKWIRSNVPGIHIPDHVIKRLEGAEDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGILKGRKPWKREHARADDMAAERMREIGSDPVQDQQEMAAKAA
HPQPH
>A0A1J5DVA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium CG2_30_51_40|TrEMBL
MNQTRAVKTDSKLEKILAAGHLAVTSECGPPRGSDSDLIKKKAELIKNHVDAINITDNQT
SVTRLCSLASCIHLKLMGLEPVLQMVVRDRNRIAIQSDVLGAASFDIRNMLCLSGDHQRF
GDSSQGQNVFDLDSMQLIQTVRRMRDEGKFLGGDEIKRPPKLFVGAAANPFADPFEIRVR
RLAKKAAAGAEFIQTQCIYNLDRFEEWMKQVRDRGLHEKVYILAGLTPLKSAGMAKYMKN
RVPGMDVPDDVVKRMSGVPKEKQPEEGIKICVESVQRLKELEGVAGFHIMAIEWEEKVPE
IVEMGGLYPRPNPDAI
>A0A8D5G089|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomarina profundi|TrEMBL
MNTESNLKKVLEAGHFSVTAECGPPRGADPEIVRKKAALVVGNVDACNVTDNQTAVVRMS
SLAGCMLIKEQGIDPLIQMVVRDRNRIALQSDLLGASALGVRNLLCLSGDHQKFGDDPQA
KNVFDIDSMQLIHLAKTMRDEGVFPSGDKLEGAPQFYIGCAVNPFADPFEIRVPRLKMKM
EAGADFVQTQCIYNMDKFKTYMEDAKKEGLHEKIKILAGVTPLKSAGMAKFMRRMVAGMD
IPDEVVNRIADEPKEKQAAKGIEMCIEQIQELKEMEGIAGVHVMAIEWEEKLEEIIGGAG
LLPRPKVD
>A0A7K1FYX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. LC2016-13|TrEMBL
MKVTEHIENAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
VMALRGDAMKDEQYFMPKAGGNDYAIDLVKQISLLNQGKYLHEVMDADNRANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFNFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLINAVDKCKNNVEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASHLF
>A0A7C5GM09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiothrix sp|TrEMBL
MDNKTYSFEFFPPKTEQGQRNLRETWETFARLKPEYFSVTYGAGGSTQARTLETVLDIQQ
SSGIHAAPHLSCVGSSKEQIRDILTTYHDNGIRHIVALRGDLPSGSRDLGDFKYANELVR
FIREETGDYFSLEVAAYPEMHPEAKSFQDDLENFVRKANAGSNQAITQYFYNADAYFRFV
DDCTALNVTIPIIPGIMPITNFKQLARFSDACGAEIPRWLRSRLAGYGDDLTSIQALGEE
VVSNMCETLLQNGAPGLHFYSMNRTEPSLAIWRNLGLPE
>A0A7Y9SJ28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. AK009|TrEMBL
MARTTSEHSAAARQLVQDYSLEMTGKDIPGLQEAQDSIPAGTKVNVTFLGNEDLEMRVAA
SKAVKDAGFIPVPHISARRLKSAEQLQEFLARLQEVGASEHVFSVGGDPAEPEGPYEDSL
SVIRSGILQQYGVREVSIAGYPEGHPDIADDILWRHLEDKIAALAEQGLDAVILTQFAFD
TDPVMAWIQEVRRRGITAEIRIGTPGPAGIKRLLGFARRFGIGANAMIVKKYGFSLTNLM
GTAGPDRFVTDLADLLAQNGTLGDVRLHFYTFGGLRATSEWVREFRAPQS
>A0A1H4DQB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. YR216|TrEMBL
MPFMPMANKEPAVRLPLSFEFFPPKTPEGAAKLRNVRQQLYAMEPEFCSVTYGAGGSTHD
GTFGTVREILGEGVSAACHFSCIGATKVTVRSQLAELKAMGVKRLVALRGDLPSGYGIGG
EFLYASDLVAFIRAETGRDFHIEVACYPEVHPQAKSPEADLQAFAAKVRAGADSAITQYF
FSPEAYWRFVDEVRALGIDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDD
TASIKSFGLDVVAALCERLRDGGAQSLHFYTMNQSVATLGVLERLGWSA
>A0A1Z4LSE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix parasitica NIES-267|TrEMBL
MLGTLNPTQLTTFRASAQAGEFLITAEVAPPKGGNPQHMVQMAATLKGRVHAVNITDGSR
AVLRMSSFAASIILQQQGIEPICQMACRDRNRIGLQSDLMGAHALGISNILALTGDPVKA
GDHPDAKSVFDLESIRLLQLISKLNNGFDSNDKALPDGATDLFVGAAVDPQCRSWSGLQK
RFERKLAAGAEFFQSQMITDFEIFEKFMNEIAAGCNKPILAGIFLLKSAKNARFINKCVP
GVEIPEHIIDRLEKAKSPLEEGMKIAAEQVQIAQELCQGVHMMAVKREDLIVPILDMAGV
KAVRR
>A0A522QSC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacteraceae bacterium|TrEMBL
MTSISLEFFPPKTDEQRAQLERALPKLKALAPEFVSVTFGAGGSTLTHTPRTVRELRERH
SFEVAPHVSCMGGSREEIGALLADYHELGCRRIVALRGDLPSGMASPGDFRYASDLVDFI
RREHDGWFHIEVACYPECHPQSDHAQADLEHFKAKVDAGADGAITQYFFNADAYFRFVDD
ARAAGVTIPIVPGIMPIANFAQLKRFSEMCGAEIPRWIGKRMLAYGDDAESVRAFGADVV
AAMCRRLLEGGAPGLHVYTLNRARATMAVLDRLDGSAV
>A0A1M6LE90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatibacillum alkenivorans DSM 16219|TrEMBL
MASKFKQALDQGKFVVTSEVAPPKGVNLEKMAHHIELLKDKVDAMNVTDHQSSVMRFPSL
GAALMVKEMGGEPILQMTCRDRNRLALQADLLFAHQRGINNVLCLTGDSVVLGDHKTAKG
VFDLDSSQLVAAVRKLEKGKDMAGNDLDGAVSFCAGAIVTPEANPIQPQLIKFEKKIEAG
AEFIQTQAVYDLENFKNFMEYARQFPVKVLAGIILLTSAPMARFMNKNVAGVTVPQEFID
EMASAPKGGAIQKGIQIAGRQIKQIVDENICDGVHIMAIGKEELVPDIMAAGGLL
>A0A1V3I5N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinivibrio sp. IB872|TrEMBL
MSYTHAGHIDALNQNIADLNGDINVSFEFFPPSTPTMEETLWNSVHRLKALKPKFMSVTY
GANSGERDRTHDIVKSIHEQTGIAAAPHLTCIDASENELRHIARDYWQNGIRDIVALRGD
LPSPEKKPDMYAVDLVRLLKEEHDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQASRFAKMTNVRVPQWMHKQYQ
GLEDDPVTRQMVGASIAIDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPLAAVS
>A0A2E6RVP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium|TrEMBL
MDRAPARRKQESXXVSPTIDQMREAQRALETPLFSGLSGDIXVSFXFFPPKNXXMNXTLW
XSVETLAPLGPRFASVTYGAGGSTRERTHQQVVRIQKEAHIPAAAHLTCVEATREQVDEV
ARHYWDEGIRHIVALRGDPPDGAXKYTPHPGGYANAVELIAGLKKVADFEISVAAYPEVH
PDSPDAQADIDNLKAKFDAGATRAITQFFFDPQCFFEFRDKAAAAGIAGEIVPGIMPVLS
FAAVQRMSGLCGTAIPHWMEGLFDGLDDRPEARKLVSATIAAELCRRLYAGGVRQFHFYT
LNRAELSYAICHMLGLRPKV
>A0A2G4HI32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MSSPSAPTPSDRPISDFFALGRPLRSLEFFPPKDDAGVEALRATATALRSISPDFVSVTY
GAGGTTRERTAQVSALLRQELGFTVMPHLTCVGHTRAELHDLADRIHAGGFRNIMTLRGD
PPKGATTFTAAADGLRYANELVALLKARHPDFCLGVGGYPEKHPEATTLEADLDALKRKV
DAGAAFVTTQLFFDNAVYYRFVEKCRAAGINVPIVPGLMPVLSLKQVQRFTAMCGAALPP
ALIKRLEVAAENTEVVEIIGLDWALTQIRDLLAQGAPGYHLYIMNRAKSALALAAGLAA
>A0A349WEA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MSKGESIGKILEKGKKLFSVEFFPPKDDAGGERMLKTAESFQPYDPDFVSITYGAGGGTR
VTTMRYAKLLQEEHGFEVMPHLTCVGHTRDELLTILEDFATAGFCNIMALRGDPPRGETQ
FRPIEGGFSYASDLVSLIRENFPHFGIGVGGYPEKHPEASNQVTDLKNLKTKVEAGADFI
TTQLFFDNQAFFKFVSDCKNAGISIPILPGLLPALSLGQVKRFCSMCEARLPPELEHHLQ
QSQESDQPGIGADWALDQVKELLNVGCPGFHLYALNKSKSTLKILEGLGRKRS
>A0A3D3BA65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp|TrEMBL
MARDDRSRDGKARLRISFEFFPPKTEEMEGQLWSTIKELSAWNPDFVSVTYGAGGTTRAP
TLTTVRRLVAETTLPTAAHITCVGATKDEVRHVAEEFLAAGVRRFVALRGDPQGGMGTAY
VPHPGGYANAAELVGGLREMGDFDISVSAYPEKHPESPDVAADIDMLKRKADNGATRALT
QFFFDNDVFERYLERVRAAGIDIPIVPGIMMIQNLMQLKRFASLCGAGIPVRLDERFAGL
DDQPQARAEVAADVAAEQIEDLARRGIADFHLYTMNRAPLVSATLERLGFARAGANLSGA
AA
>A0A077LZ84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetrasphaera japonica T1-X7|TrEMBL
MTRPSPSRRSVVGRHLVAERPDAQPSIPDLLRADGVAVSFEFFPPKDDAGEAALWDAIRM
LERMRPAFVSVTYGAGGTTQDRTVRVTERIARDTTLTPLAHLTCVGASRTALRHVVGQYA
AAGIRNVLALRGDPPGDARGTWVPHPEGLDHADALVRMLRSLGDFTVGVAAFPDVHPESG
DLDEDVETLVRKADAGATFAVTQMVFDADTYLRLRDRVAARRDLPITPGLMPVTNVRQIA
RMSYLMGTPLPPRIVERLDAVADDPTAVAAVGVEIATELGERMIAEGAPGLHFITMNRST
ATLEVHANLGLGPATERPVA
>A0A1M6DQE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatibacillum alkenivorans DSM 16219|TrEMBL
MSLNTESKLEKILKAGHLAVTSECGPPRGTSLDKIEEKANLIKDCVDAINVTDNQTSVTR
MCSLAACIKIKLMGLEPVLQMVTRDRNRIAMQSDILGAAAFGVNNMLCLSGDHQSFGDCA
TGQNVHDLDSMQLVQTVRHMRDEGKFLGGGDIAGPPKIFVGAAANPFADPFEVRVPRLAK
KIAAGAEFIQTQCIYNVEKFEKWLEIARDRGLTEKVFILAGVTPMKSAGMARYMKNRVPG
MDVPDEIVKRLSDTPKEKQADEGIKICIETMQRLKEVKGVAGFHVMAIEWEEKVPELVEG
AGLYPRPEVD
>A0A1I5L4R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. NFR06|TrEMBL
MTAHQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFIQTQYCFDVPMFRTFMQKARDLGHTERVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A8J5TWP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. rapae|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFEATLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLIARLDAVKGDDERVKMVGVDIVSELIEKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKARLTSPELQDSVCFYASNARGDYLSSDNSDHVNGSAEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A3D0E7J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp|TrEMBL
MNLLDSLKERILIGDGATGTLLYSYGVDRCFEELNLTHPDDIFHIHEEYIKAGAEVIQTN
TYSANYIKLARYGLEERVKEINSGAVKIAKSAAQKNAFVVGTIGGIHGARFHSELREEIK
RSFREQLYCLLIDDVDGLLLETYYDLDELTTVLEIARQVTDIPIITNVSMHEPGVLENGI
LLSDALKRLEDLGADVVGVNCRLGPYHALKALETVPIPGKAFLSAYPNSSLPEFRDGKLL
YKSEPEYFKKFAVHFRDEGVRLMGGCCGTTPDHIRAMKEGIKNLKPIKKKNVKKQERLEI
SETKKPDELTLFEKIKAKRSIIVELDTPKHLNTRKFFDGAKALKEAGIDGLTIADNSLAS
PRICNKTMASLVKRDVGLSSLVHITCRDRNLIGLQSHLMGLHTLGIRDILAITGDPTKIG
DFPGATSVFDVTSFDLIKLIKQCNEGISFSGKSLKQKTNFHVAAAFNPNVHNIEKSSERL
EKKIQSGADYVLTQPVFSQEKIIETWEATKHIEAPIYIGIMPLVSSKNAEFLHNEVPGIK
LTVETRKRMDIARDPEKAVLTGLDIAKELIDTAIQYFNGIYLITPFIRYELSVELAKYIQ
QKTTELDEKRSSQFVLS
>A0A3D5U4W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7Y8V0V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp|TrEMBL
IQTNTYSANYIKLAQYGLEEKVKDINKAAVQIAKEAANRDTFILGTVGGIRGQRKTEATL
AEIKRTFREQIFHLLDEGVDALLLETYFDAEELYTVVDIAKKEADVPVIAQFSLIEPGVL
QNGTPVRDAFKELENRGADVTGLNCRLGPHHMIQAFEEIPIPKRAFLSAYPNASLLDYEE
GRFTFTNNADYFKTCAEKLVEQGVRLIGGCCGTTPAHIKAIADGVQGLLPVTEKTVRPPK
IEIAAAPAQHEPPLHEIVKKRRSVIVELDTPKTLNTTRFFEGAKALHDAGIDALTMADNS
LASPRISNTAIASILKEKHGIRPLVHITCRDRNLIGLQSHLMGLAALGIDQVLAITGDPT
KIGDFPGATSVYDLSSMELIAMIKQFNDGISHSGKSLHRKTNFSVAAAFNPNVRNLDKTV
GRLERKIRYGADYFITQPVFSTEKIEQIHEATKHLDAPIYLGIMPLTSYRNAVFLHNEVP
GIKLTDEILAAMEKTNGDPAKAREESLAISRTLIDAALGYFNGIYLITPLERYELTVECT
RYIHEKTAVQGAGIV
>A0A0Q8VRP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces sp. Root81|TrEMBL
MASTATDAAGADCRPRLPLSFELFPPRTDAAALALGRTIDRLAEVDPAFISVTFGAGGSS
RERSLTVLRYMLEHTHVEPMAHLTCVGSSHAEANRLVREFLDAGITSFLALRGDPPADAD
PDAGIGDLGSAAELVQLIHRVQEEREPFGQVDVPGNPGASRIRARPRPERVAVATFPTGH
PRSRNLGHDVDTLLAKEIAGANLAITQLFWRADDYLGFVERARAGGVTIPILPGIMPVTT
PARLARLTELTGVEPPAELAIDLEIEPDAAAQTELGIAFATRLASDVIEGGAPGLHLYTF
NRHEAVLDVVDRLGLRAHRLADERNTAR
>A0A1F8PZ34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_54_18|TrEMBL
MAAPVIDSQKQNSNGYYSGSTLEKMLRQGHFAVTAELGPPQSADGDVIRKKAALLRGFCD
AVNITDNQTAIVRMSSIGAGVIAIQEGLEPVIQMVCRDRNRLAMQSDLLGAYALGARNLL
CLTGDHQTFGNHPESKNVFDLDSIQMVRMVTAMRDERIFQCGEAMKGQEPRFFVGAAESP
FAGPVEFRPYRLAKKVKAGANFIQTQLVFDVSAFAAFMEKVRELGLHDQVYILAGVGPLK
SPGMAKYMKEQVPGILVPDRLLKRMEDVGLPWAGKKGEELTKEDKKARSEAYKQEGIQVC
IELIQQLQQIKGVAGVHIMAIEWEEAVKTIVEGAGLYPRPQVD
>A0A2T4A6C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma harzianum CBS 226.95|TrEMBL
MDKITEKIAALPPDGEYFSLEFFPPKTAMGFSNLRVRLQRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREIGLTTCLHLTCTNMSQALIDQALEDARALGIRNILALRGDPPRAEY
RDADEPDQTASEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPY
LVEKVQAGADFIMTQLFFDIEAYEKFETTLRNHPSGAFKTIPILPGLMPIQSYAMIKRTA
KLSHAKIPEETMARLNAVKGDDEKVKMVGVDIVSELIGQIREIKSRTPGPKGFHFYTLNL
EKSISFILERTKLIPDVPDDEEAVVDEPVAAAAQLVVPKISVNGNVPPRSSSHARTGRRQ
SSVGSDPHNRVIVGRAATHPEWEATSTEAGIPAESVNTRANTLAISEGEGALGREATWDD
FPNGRFGDARSPAYGEIDGYGVSIHMSVTQAVRLWGHPKVASDINDIFVRHIRGEISAIP
WSEEDLLPESSIIKSKLEAMNRKGWWTVASQPAVNGLPSTDSTFGWGPASGFVFQKSFVE
FFIPSADWKILYDKLTSAEVEEVVCFYASNAKGDFISSDASGGSGRAVMSASTNAVTWGV
FPGKEIVTPTIIEEVSFRAWSEEAFDIWAEWAKVYGRGSDSQKLLDEIKEDRWLVNIIHH
DYVDTEALWRLLIE
>A0A087AFT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium choerinum|TrEMBL
MPIFSLEIFPPKRTAPVGTIYDTLDGLQGLSPAFISVTYGTGKSVDRTATARIANTVRAE
YGIPAVAHLTAQYLDEAGAEEALDLFDQAKVAGVLALRGDRNPEREPANVFHHASDLAAF
IRERRPDLPIYGACYPEKHPQAASLDEDIDNLKRKVDAGVTHLISQLFYDDEDFLRFRDK
ARAAGIDVPIEAGIMPVVNAGSVRHMADLCASRIPERLAVMLEMWGQDPASLKEAGIVYA
SEQIRDLVARGVDGIHLYTMNRPCAARRIWANTKAFFA
>A0A222WVP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomonas fulva|TrEMBL
MTLSLKQLAEAREALGTPLFAGLAGDVEVSFEFFPPKTEKMEETLWDTLTTLAPLKPKFV
SVTYGAGGSTRERTHATVARIAAETAIPAAAHLTCVDATRDEIDEIAQNYWNAGVRHIVA
LRGDPPRAGEKFSPHPGGYANAAELVTGLKKVAPFEISVAAYPETHPDADCADSDIDNLK
RKIDAGADQAISQFFFSPEAFFRFRDAYTKAGITKPILPGILPVSNVATTRKIAGMCGTA
IPQWMNDLFEGLDDHPTTRQLVAATVAAELCRRLYSGGVRHFHFYTLNRAELSFAICHLL
GLRANRHAQAAPVLQENAA
>A0A3D3KRK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp|TrEMBL
MFPTRIEIIPSTGIIDQVQALVPLTTTLTMTCLPHHGIERTMRTSVELSTLGYTVIPHLA
ARSINDRAELTRIMRECDVAGIGEVFVIGGDRKQPAGPYGSALPLLEDIAQYTGGRMRAG
VAGYPEGHPTVAALDLLDALQDK
>A0A396U2S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colwellia sp. RSH04|TrEMBL
MSYSHARQVESLNRSLSEISDDIQVSFEFFPPNSPEMETTLWNSVERLAPLKPSFVSVTY
GAGSGTRDRTHDIIKRIQKDTALLAAPHLTCIDAGRDELVQIAKDYWESGVRHIVALRGD
LPNSNEKPNMYASDLVELLRDVADFDISVAAYPEGHPEAPNPQFDLLNLKRKIDAGANRA
ISQFFFDIESYLRFRDRCVTVGIDVEIVPGILPVTNYKTLERFAGLTNVHVPSWMTKMYD
GLEDDEMTRRMVGANIAMEQVKVLNREGVKNFHFYTLNRAELTYALCHTLGIRPQK
>A0A6M5JJM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. AP4-R1|TrEMBL
MSAPLYADVAGDIGVSFEFFPPKTEKMEETLWSAIQTLAPLGPRFVSVTYGAGGSTRERT
HQTVARIVRETGIPAAAHLTCVEATKDEIDQIARDYWDAGVRHIVALRGDPPRAGEKFAS
HPGGYENAAALTAGLKAIAPFEISVAAYPECHPDSADPQADLDNLKRKIDAGADRAITQF
FFSPETFFRFRDAAAAAGIDAEIVPGIMPVSTFAATSRMAAMCNTDVPEWMARLFDGLED
HAAARQLVAATIAAELCRKLYAGGVRQFHFYTLNRAELAYAICHLLGKRPAKAGGTLEAA
A
>A0A6M6JQK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia broussonetiae|TrEMBL
MKITDRIGGDQPVFSVEFMPPKDDAGEAELWNAIRRLEPLDPAFASVTYGAGGSSRDRTV
RTTGRIASETTLVAMAHLTAVSHSVAELRHVIGEYAAAGIRNVLAVRGDPPGDPLGEWVA
HPEGLMYADELVSLVRSLGDFCVGVAAFPYGHPRSADEDSDLQRLVAKVRAGADFAITQL
FLEPEGFLRLRDRLSAAGCEVPLLPGIMPLTTLRTLHRGPELSGAPLPPGLAERLERYAG
DPAAFRRAGMDLTTELCARLLAEGVGGLHFYTFNRSTATTELVQRLGLGARRGVAVA
>A0A6H9WQU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoclavibacter endophyticus|TrEMBL
MTGKQKDIDDLREAAPLLPAGTRVNVTFLGNENLEMRIAASKAVLELGFTPVPHVSARRL
HSEAELTEFLAALQEIGASKHIFSVGGDPAEPMGPYGSSLEVIQSGLLPQYGVEDVSIAG
YPEGHPDIASDVLWRELEGKAVSLREQNLSGVILTQFGFDTDPVASWVNDVRGRGIDFPI
RIGTPGPAGIKRLINFAKRFGVGANAMIVKKYGFSLTNLIGTAGPDKFITELGDLLAAKE
SAGDVGLHFYTFGGMTATSKWAQEFTARQEAAK
>A0A2S6T3Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha5_Bin1|TrEMBL
MEYQSLLHKKLLDGNFVYTAETTPPDSADQEVILTKTKPLKYIADAVNLTDSPGAKVHMS
ALTAAIILAQNDIEPILQLTVRDRNRLALQGDLVGASALGVHNILCLSGDDPKIGDQPET
IAVNDIDSLTLVATADLMRRKGKFPSGRLIEPPPKLCIGGAEVPTEGKPNTEKILNKIKT
GINFFQTQYVFDKKILKEYMKVLDDVGILEKTFFIIGLGPFTSAKSAKWMNNNLFGVNVP
EKIIKRLEQSKDEKEESKKICLELIHHFKEINGVKGVHLMGHNKEEIIAEIIQESRKNNN
>B9XQY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedosphaera parvula (strain Ellin514)|TrEMBL
MHNRQLMQFIRDIYAAKADAHQPVISFEFFPPKTDEGDRALLEKTIPALLRLKPDFCSVT
YGAGGGTRDKTLMIVDRIQREHQLPTMLHLTCVNATREQLRDVIEQARSLGVKNILALRG
DPPGGNGEFKMTDGGFEYSHQLVALLRELGGFSIGTAGFPEGHIACKEGKHVDWEHLKKK
IDCGADFVVTQLFYNNADYFEFRDHLTKKLGASVPIFPGILPILSAGQIKRISALCGAKL
PSRLVSCLEKLADNDEAAAAYGIDYATEQCAELLREGAPGLHMYTLNKAPSTIQVLKNLA
LAH
>E0UPV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas autotrophica (strain ATCC BAA-671 / DSM 16294 / JCM 11897 / OK10)|TrEMBL
MFDTLIEKLKNDTYITLETTPGHSATFTPTIDKIEALGLAELIDGFSTTDNPLAKLKYNA
LFAAKLLQDRFNKPVIATMSMRDRNKIALQSDLLGANEFNIRAILALTGDPATISDQPNT
KGVFEADSSLLLDIIAALNSGMDYAAKPFSVAPKHIHPFAVVNSYAKNPKILQKKMQKKI
KHGAIGIITQPVYDLENAKQLLELKDNANKECCRENKNAELILGVFPITKLRTAQFLASH
VPGINVPPCWIDKLRQANIKGVEEEYKVGFELSKKLFEDLKQLHPKIHLMTANQFQIAKE
ILL
>A0A3G7HJE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas chlororaphis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLDNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>S0G244|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotignum phosphitoxidans DSM 13687|TrEMBL
MSKYVSSSRLERILKAGHLGVTSECGPPRGSDAEEVTKKGLLIKDYVDAVNVTDNQTAMT
RMSSLAACIHLKLLGIEPVLQMVTRDRNRVALQSDILGAASFDISNMLCLSGDHQSFGDC
ARGQNVHDLDSMQLVQTVRHMRDEGKFLGGDDIKRPPKIFVGAAANPFADPFEIRIPRLA
KKIACGAEFIQTQCIYNIDKFKEWMRRASDRGLTEKVFIMAGMTPMKSVGMAKYMKNKVP
GMDVPDEIIQRLAGVEKKHQAQEGIQICVEHIQELKEVPGIAGFHIMAIEWEEKVPEIVE
KSGLYPRPDM
>A0A0Q7GIG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. Root420|TrEMBL
MKVTEHIENAKGNTLFSFELIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKLGGNSFAIDLVRQINNLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQIF
>A0A1Q7W5B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_1_20CM_3_71_11|TrEMBL
MAHGLPSVMPGGQPSIGELIRGTAPTFSFEFFPPRDADMDRQLWRAIRELESLRPSFVSI
TYGAGGSTRDNTVAVTERVATETTLLPMAHLTAVNHSVAELRNVIGRFAGAGIRNVLAIR
GDPPGNPQGEWIRHPSGVLYAEDLVRLIKDAGDFCVGVAAFPYKHPRSASVEADTEHFVR
KCRAGADFAITQMFFDAEDYLRLRDRVAAAGCDTPIVAGIMPVTSMRTIERSEQLSGAPF
PPALAAQFERIADDPAAVRRLGIEQAGALCERLLAEGAPGIHFITLNRSTATREVWQQLA
LGARA
>A0A2H6K665|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Abin01|TrEMBL
MRSGSTLEKVLKAGAFAVTAELGPPKGADAQVIIDKANILKGHADAVNITDNQTAIARMC
SMAAARLVIDQGLEPIMQMTCRDRNRLAIQADILGAAALGVKNLLCLTGDHQSFGNHPQS
KGVFDLDSITLINMVKDMRDVPAFQCGEEITMAPELFIGAAANPYADPFPFRAIRLAKKV
DAGIDFVQTQIIYNVEKFEEFMAQCRELGVSERCHILAGVAPLKSAGMARYMKKRVAGMD
VPDQVVERLSSATDAQDEGIDVCVEVIERVREVEGVAGVHIMAVEWEESIPEIMKRAGLK
PGSASL
>A0A6I3B828|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSPTRTAPSLGAVLAGGGHSFSFELFPPKTDAGEQALWQTVRELEALKPTFVSVTYGAGG
STQDRTVRITKQIAEHTTLLPVAHLTCVDASVDDLRRVIAQYSDAGVNTIMALRGDPIAG
PESRWVQHPGGLQHADELVALVRSLGAFSVGVAAFPEGHPESGDFEEDARVLAAKQDAGA
EFAITQFFFRAEDYERLVTRAAAHGCTMPIVPGLMPVTNVAQIERFAVLSGAQFPSELAD
KFGKIKDDQGAVHELGVEVAADLGGKLLAMGAPGLHFYTLNRSTSTREVYEALGLNEV
>A0A7C3X8P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSPGAASRLAALHERGALSVTSDLHPPRGTDFSAFRRGAEALEGLVDAVFVTESPGAVVR
MGSLSGCIYLILETSLEPVLQMVCVRSNRIALQGELLGAAAWSVRNLLLLGGDSSRYGND
PRAQDVRCLDTPDLIRLACAMRDQGVLSDGAPFEGKAPFYIGAAVDPFGTPEERERTRRK
LESGAEFLVTQPVFDVDAFATWCEETGSELGKARLIAGVLVLGSARAASRLSGRLPGMRI
PEGILRRLEEAEDPVREGIEIAAETAAELSRIPRIAGIHFMNASGPENAAAAIRLSGLRT
>A0A6L6A8Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNEAKGRELTYSFEFFPPKDSEGEARLWSAIEGLESIAPDFISVTYGAGGSTRDRTIRIT
SEITARTNIPTVAHLTCVGSTREELIEILAKYRAAGISSILALRGDPVGGPRAPWQVTPG
GFNHADQLVALAREIGGFTIGVAAFPDGHPASADGLDDDIEVLLNKERAGASFATTQFFF
EAEKWSALVEKLAAKGSSMPIIPGILPVTNVKQLNRMSELSGTPIPTDIAEAFAAVEDNP
DDVRKLGVEIATKLCRDLIAAGAPGLHFYTMNTSSATREIFEAIK
>A0A7K1BM80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTYISDLLAAGRTCSFEFFPPKTDDAARALEQTIAELEPLDPSFVSVTYGAGGSTRERTR
DVVINIERNIGITAMAHLTCVGHTRAQLDSLLDEYKAAGVSNILALAGDPIVDDNGVVAE
SEFEFAMELVELIKEKSGFSIGVAAHPEGHPRSEDLYSDRRHL
>A0A7C3T0H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKSGSNLEKVLEAGHFAVTAEIGPPKSASARVIEAKGEQIGHAADAFNVTDHQTGVVRLC
SLAACAILRRMGLDAVMQMLCRDANRIRLQGDVLGAVALDIRNILCLSGDHVKFGNHPEA
KRVFDIDSVQLIKAVKDMRDERRFICGEEVGSEVPLFIGAVENPYADPFEFRTARLAKKV
EAGADFIQTQAVYDVPKFRRWMEEVCEAGLDKKVHILAGIIPVKSVGMARYMQRYVSGVE
VPDEMIKRLEGAKDVREEGIRIILEIIEEVKEIPGVHGIHVQAVGWEEVVPEIMERAGLL
PRPVL
>A0A2N5KM77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRRSVLHLISAPRHGSLYTQRGVCFLDLREKLDGRLLVGDGAMGTLLAERGVGYGHPYDR
ANLTHPHVVRAVHEEYVRAGARVIETNTFSANATKLALKNLGDQVREINVEGARLARSAV
ENALPNGDDAIVLGAVGPLGRPLAPIGPIRPEEARAAFMQQAEALLEGGADAILLETFVD
LAELKIAYDAVASLGVPVIAHKTFVEDGETLAEGLPARVARDISSWGSEGLLLAGSNCTV
GPQRMLGITEAMASEVGPVAAYPNPGLPQLVNGVVRYNRDVEHFAEYGLKLAQAGAHIVG
GCCGTTPSHVRALAEALRDFKPAARSARRVSASTPELETEKAAAEPETEFARKIKEGFAV
AVEVDLPRGHDISGVVEAAKALKERGVHAIDISDGARARLRMHPIAVARLVQEQAGIEVV
AHMSCRDRNIIGLQADLLSAAALGVKNILAVTGDPAQIGDYPEATSVFDTDAVGLVHVLS
KMNRGEDLAGNPIGEPPGFLIGASFNPTAEDLDAEVDKLWRKVGAGAHAFWTQPVFELGA
LERALEKIQDMDVTLLLGLMPLRSGRQAEFLHHEVPGINIPQSVRKKLAELAAEDAPKYG
VEVAQNLLAKAKPLVGGAYLMPPASMPHLAGDVIEAVG
>A0A6I2ZST2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MERMTVSVEFFPPKDDAGEARLWEASAALESIAPDFISVTYGAGGSTRDRTIKITKEITE
RTGRNTVAHLTCVGSTKEELVEILAQYRSAGIKSILALRGDPVGGPAANWVTTPGGFDHS
DQLVELAIAQGGFEVGVAAFPDGHPASNNNLDRDIKVLLRKEELGATFATTQFFFESSKW
ESLVEKLATRGSKLPIIAGILPVTNVKQLHRMAELGGTPIPEKISKLFSEISEDPDAVRK
AGVDLATKLCAELIAMKVPGLHFYTMNTASATLEIYKNLGLPSRG
>A0A6I3G5E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTVPVSFEVYPPRSPEKLPGLKESIRVLDSVSPDFISVTFGAGGSSTRDSLEVLRFIRDE
SSATPLAHLTCVGTTRQEASELVVSFLAEGITHFLALRGDLPEGALEHRGELHNAVDLVT
LMHELPDMPKPLERIAVAAFPNGHPESDSLDHDVETLLRKQEAGATLAITQLFFFTEDYL
TFVGKAHGAGITIPILPGLMPVVSPSRLNRVVELSGENRPAELSEALSSTEDAAAREAIG
VDWTAKMVRELVDAGAPGIHLYAFNQHRTVLSVLEQSGVR
>A0A7K0NL05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MLEVSSLSTAQRYSEAVDKSSVRSGVTYSFEFFPPKDVEGEERLWSAMSQLENISPDFIS
VTYGAGGSTRDRTIRITSEITARTHIPTVAHLTCVGSTRSELVEILGKYRDAGITSILAL
RGDPTGGPRAPWVPTQGGLNHADELVTMAAEFGGFTIGVAAFPDGHPSSHGDIDKDIEVL
LEKERRGATFATTQFFFEVDKWKALVDKLAAKGSSLPIIAGILPVTNVKQLNRMAELGGT
PIPASIAERFAAVENNPEDVSKLGVEIATNLCHQLLESGAPGLHFYTMNSSTATREIYSQ
IKDDR
>A0A7V3BWM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKVIEHLANATRPLVSVEIIPPRRGGDVQRIYDAVASIMPFDPPFIDITSHAAEVVWLEQ
PDGTWRRKVMRKAPGTFGLCAAIEHRFGVDPVPHVLANGFTREETEDALIELNYLGIENV
LVIRGDGDPRPPADGRSVNESGLDLVRQVAAMNRGVYLEELLESTPTDFCIGVAAYPEKH
VEAPNLEWDLGVLLEKQRAGAHYAVTQIFYDNEVYFRFVKAARNAGVTIPIIPGLKILTR
REQLRVVPKHFGVTVPEALVEQVMAVEPERAVDVGIAWALEQTRELFDRGVPSVHFYVMQ
NTAPLVRLMEQLERD
>A0A7K0PHS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDEIIETSADPTFSFEFFPPKTDEAEALLHDALETLRELSPSFVSVTYGAGGSSRDRT
IKVVRNLRVEHGLEAMAHLTCVGATKDEIRTVLGQMRDAGIDNVLALRGDPPGGEEKFSP
TPGGFASSPELTALVDEEFPFCVGGAAYPEPHPDARHDDDDVQTAKAKVEAGAKFLVTQI
FYDNSDYFSFVGRLRDEGIDVPVIPGLMPITSIGQSRGFLKKIGARIPEGYRAELDARED
DPDAIKSLGISYATLQAAELLAQGAPGIHFITMNRSPATRAILATLRLHRPWERTPESPA
STGGQPSLA
>A0A7V9P5F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MEERDALAFHLSQPRYEVVPAAGIEDEVAAHVPRGLKVTVTASPRRGIDATLDAAEELAR
RGYHVAPHLSARLVRDEAELREILARVREAGLTDAFVVAGDLDQPGGAYESAVDLLRAMD
ELGHGLAHVGITGYPESHPVIPDRTTIEAMDEKAPYATYIVSQVCFDPATIVSWVHAVRA
RSVALPIDIGIPGVASRVKLLRIARRIGVGDSLRFLGKRRGWLAQLLTRSGYDPAPIVEG
VASILPDPAARIAGFHVYTFNEVEATERWRREALARLDAV
>A0A7K0ZHI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MASAHHQFAALASSHHRLAALASSRHRPIVTAECPSADGGTIDDLAARLATIAPFVDAVN
VTDNPAAHAHASNVSMAIALAGLGIEPIMQIVCRDKNRLAIQADIAGAAMFGIVNFSALT
GDDVTAGDEPEARRVFDLDGPQLVSVLAGMKAGTYLSGRKFTPTGDFFIGAVENPGAPPL
DYRADRALLKVNAGAQMLQLQISYRPDQLEAFMSACVANGVAQRAIVLPSVCLTKGARAL
SFMNDKVPGISVPAETIDRVANADDQAEEAYHLVRDLTAHALQLPGVAGIHITDFRHDGS
VQRLTEELRIGPRFDSAIAETGTNPEHEERHAHSS
>A0A7K0R7C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDDILRSGTDPVFSFEFFPPRTPAGEEQLYEAIAKLAPMHPAYVSVTYGAGGSTRGKT
LEIVSTIRERHGIEAMAHFTCVGATVDDLRETLDEMLRLGFENILALRGDPPAGQDEWVR
TEGGLEYSRELVELIRAGYPMAIGAAAFPETHIHATSPQDDLRHLKEKVDAGVDFLITQL
FFDNAVYFDFVSRARAIGIDVPIIPGILPVTNIAQLDRITALCGSEVPAGLRAELDLRAE
ELEAVEDFGVAYATLQCAELLAGGAPGIHFYTLNRSPATRAILGALRLQRPWDPARA
>A0A7K1BH15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVLGTSYSFEFFPPKDVEGEERLWHAIEGLKSISPDFVSVTYGAGGSTRDRSIRIAREIT
DRTGISTVAHITCVGSTRAELLEILHSYKDAKITSILALRGDPVGGPLAPWIPTEDGLTH
ADELVELARDCGGFKIGVAAFPDGHPSSGGNFEKDIDVLIRKEQLGATFATTQFFFDVKA
YANLVERLAKRGSSLTIIPGILPVTNVKLLHRMAELGGTPIPSHIAKSFADVESDSQAVR
NVGVEIATKLCQELLEVGAPGLHFYTMNSSTATIEIYRRITDAQ
>A0A6I2X634|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGGSLQIPTLSFEFFPPKDADGSVALSNTLETLAAYNPAFASITYGAGGSAQERTFAAAT
IVKDQLKVPTVGHLTLVGATQTELESVLKQYEALGLSGVLALRGDPVGGPAAEWTPTPGG
FDYADQLVQLAKTSTNLDIGVAAFPDVHPGSNGNFMQDIKVLLRKEELGATFAITQFVFD
SGRFEALSDALVARGSKLRLYPGIMPVTNYTMILRMLELSGGYMPKATRLRFARYQNDVE
SLKALGIDIAVQICEDVIALGADGLHFYTLNQSGPTKAVLDQISHF
>A0A839PAN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. RMAD-H1|TrEMBL
MSVHELKSREAKTMTHIGASIELAPKQAIESQDLPGLFPAGSRVYITDIGTDSVDTMTAA
AKRVHDLGYKPVPHFACRRLTTRQALETRIRRAAEEAGVTDVLVIGGGLERPAGEFNSTM
QVLETGLFDRYGITEMGVAGHPEGSPDFSEAVAVEALRLKKNFGERTGAKLRIVTQFGFD
ADHFIAWAEGLREAGIDLPVHLGVAGPAKITTLIKYAAMCGVGNSITFLKKNALALTALA
TTHSPEGVVGPIERHVLENPTSNIKQIHVFPFGGIKKASEWLVERGTWNSNTSSPIAAAQ
QGNKHI
>A0A7K1E5T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVLGTSYSFEFFPPKDAEGEERLWHAIEGLKSIAPDFVSVTYGAGGSTRDRSIRIAREIT
DRTGIPTVAHITCVGSTRDELLEILHSYQDAKITSILALRGDPVGGPLAPWIPTENGFAH
ADQLVELARDCGGFTIGVAAFPDGHPSSGGDFNKDIDVLIRKEQLGATFATTQFFFDVQA
YVNLVERLAKRGSSLTIIPGILPVTNVKLLHRMAELGGTPVPPDIAKAFADVESDTQAVR
NLGVEIATKLCQELLEAGAPGLHFYTMNSSTATVEIYRRITNAQ
>A0A7K1DLC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARISDLIAAGRTYSFEFFPPQTQAAQMSLGRAIAELSPLAPSFVSVTYGAGGSTRERTR
EVVTWVRKETDITPMAHLTCQGHRRSEIKEILDNYADAGVENILALGGDVPLDGEVQPSD
YTFASDLLDDVLADGRFSVGVAAHPEHHPRSPDRATDRRYLAAKLGSSDFAITQFFFEVD
VYVRMVDELRALGVDKPVLPGIMPVTNKSQILRMAAMSGAAFPEWLAQRLEAFEDPEDIR
RVGVEAATELGQALLDAGAPGLHFYTLNRSTATREIYANLGLPIEQ
>A0A537YG88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MLKRSEFADLVAEQPLLADGGTGTTLVARGVRPDACFDALNVAARDLVREVHESFVEAGA
QVVETNTFGANRYKLAAHDFAFRVHEINVAGVARAREAGARYVAGSVGPLGVRLAPYGRV
PKDEAQEAFAEQIRGLVDGGADLLILETHSDVAELEQAVLAARAVTDLPVIASLTFTRDD
RTLLGESPEAAAARLAGLEVDMLGVNCSEGPEQVLRLITVMKPHAGGIPLVAQPNAGGPQ
RLGGRIMFSATPEYFGEYATAFVAAGVRLVGGCCGTQPAHIRAMASALAAPARPLDIEVE
EQPAEPADVRMPSERPTGLATKLASRALTIAVEMEPPRGFSAARLVAGADTLRAAGADVI
NVSDMPTARMRMSAWAACHLVQQEAGIETVLHFPTRGRNLLRVQGDLLAAYALGIRNIFA
VMGDSTSIGDFPEATDLSDVTPSGLIALVKGSLNAGLDRAGSSIGDPTSFVVACALNVTA
SDLEREARVLKRKIDAGADYAITQAIFDAERLDRFRALYEEQYGPLELPILGGVLPIASR
RHAEFLHNEVPGIDIPDAIRKRVGKAADERAEGLAVAVNLCDELRARVAGLYLIPPFRRY
DHAAELIELVRS
>A0A7V2VI93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoflexia bacterium|TrEMBL
MIAGSNLEKVLRAGHFAVTGELGPPTNADKSIIDEKAEHLRGVVDAVNITDNQTAVVRMS
SIAVAAMLIEKGLEPVVQMTARDRNRIAIQSDLLGAWALGAKNLLCLTGDHQIFGNHPEA
KGVFDMDSIQMLAMMRDMHEKGIIQSGDDIDVPPTFFLGAAANPFAPPYEYRPYRLAKKI
QAGAKFIQTQCIYNMPRFKEYMQRAGDMGLLDNVYVMGGVTPLKNVGMAKYMAKSVPGLD
VPEEYIDRMRGATSGIPKENKKARRQALREEGIAICVETIQQLQEIPGMHGVHIMAIEWE
SAVPIIVEKAGLFPRPSV
>A0A7Z8KZI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides zhangwenhongii|TrEMBL
MKVIDLIHNNKKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELVKEALKCKTDAEAEQVGIEWCVAQCKELMSHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A177PAM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylosinus sp. R-45379|TrEMBL
MMSDNRSLWPPGHFDISYEFFPPKTPEMEAQLWDSIARLAPLKPKFVSVTYGAGGSTRER
THNIVARLAAETDILPAAHLTCVSAARAEIDEIVRGYWNVGVRHIVALRGDPPTGVGTRF
EPHPQGYRSSTELVRGIRAIRDFEISVSTYPEGHPESRTIDDDLDALEAKIDAGATRAIT
QFFFENDVYFRFLDKARARGIKIPIVPGIMPVQNFKQTANFARKAGASVPDWLAHRFEGL
DDDPVTRRLIAAAVAAEQVLGLAEGGVKEFHFYTNNRADLVFAICHLLGVRPVTEKVAA
>A0A2W4NF22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSLGRASRLIGRAPTVRELLATGERSFSFEFFPPKTPEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVEIVERITHETTLTPVAHCTAVNHSVRELRHLIGRFAAAGVRNILALR
GDPPGDPTGEWVKHPEGVEYAEELVRLIRQSGDFCVGVAAFPYKHPRSPSIESDTEYFVR
KCRAGADFAITQMFFRAEDYLRLRDRVAAKGCDTPIIPGVMPVTQYSTIARSEQLSGAPF
PADLAERFARVAHDPAAVRALGIEHAVEMCRTLLDEGAPGIHFITFNRSSATREVFQALV
PAGVSVGA
>F1ZCK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium nitrogenifigens DSM 19370|TrEMBL
MSLVPPLSPPTHADEEPLFADMAGDINVSLEFFPPKSDAMEVQLWEAIEALAPLDPSFVS
VTYGAGGSTRERTHATVARLVRETSLVPAAHLTCVGASRGEIGEIADRYWDAGVRHLVAL
RGDPPPSAGGRFVPHPDGYANAAELVAGLAARHPFELSVAAYPEVHPEATSAQADLDNLK
RKVDAGASRAITQFFFSTDAYFRFLDRALAAGITVPILPGIMPVTNLSGIRRMGGNVQIP
DWLERMFAGLDDRPGSRALVAAVVAADMCRRLYNGGVRDFHFYTLNRADQAFAICQLLGV
RPKETV
>A0A2J7Z8T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces malaysiensis|TrEMBL
MRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSVTYGAGGSSREGTVRV
TERIATDTTLTPVAHLTAVNHSRAELRNIIGQYAGAGIRNMLALRGDPPGDPMGEWISHP
DGLDYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIGHFINKCRAGADFAITQMFF
YPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIDYATELCARLMAEEIPGLHFITLNHSPATLEIYENLGLHQRS
>A0A3C0LC15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MIHHIQNKIYHVEVLPPKQDSEKLEKDLEIFSNKYLRVMDSGYCACITDNAMGLLSFQGT
EMIEELDLPVIPEQVMIHLSTFHTKDDLDNILDICKTKGIRHLLIITGDGSERLPKLQPS
DVGATDVESVTSVDLLKYINHGYPDTFVLGVAFNPYEPEEHEFEKMERKMKAGATFIITQ
PLIERNEVVDRLLEKYPEIPVIVEAWMSRKLHLLSEAVGYEIPENTEFDPISTLKMLHKL
YPGCGVYLSLLGFKTQYDLIKDIWV
>A0A538B365|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPKIAELLAAGPTYSFEFMPPRTEEMLRTLEKTLLELEPLGPSFCSVTYGAGGSTRDNTL
EAVLYIHHDTSMLAMPHLTCVGQTRDEIEALLIRYRDEGLENVLALAGDPPADGPVTGDF
TYSCELIELARSIADFSICVAAFPEVHPRSPDRRSDRRYLAEKLRLADFAITQFFWTADH
YFRMVDELDALGVTTPVIPSVFPVINVATAKRFTSVNGAEFPASLAERFDPVADDDDEVR
KIGVEVASELGQQLLSQGVPGLHIYTLNRSASAKEIWRNLGLESTDA
>A0A4P5QYT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRVSDLLARGRTYSFEFFPPKTDEAQAQLATTINELTPLQPSFYSVTYGALGSTRNRTRD
VVVDLARNGTIPPVAHLTCVGQTRTEIDSLLGDYKAAGVVNILALGGDLPADSSQLGPSD
FRYALDLVEHLRANFDVCIGVAAHPEVHPRSVSREMDRQHLAEKMRLADFAMTQFFFDVE
HYRRLLDELAALGVTKPVIPGVMPVTNKGQIVKMAQMSGAALPTWLTDRLAPLEQPEDIR
KLGVEVATQLSSDLLAAGAPGLHLYTLNRSVAPREILSNLGLS
>A0A380N7H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella atypica|TrEMBL
MTLREKHQKGQFTITVELDPPKSSSAQKVFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNEGIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDHGDHPFAQSV
FEVDCMGLLNIAKTLNSGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNGA
HFVQTQPIYDLEQAKRYIDKMSEFNVPIMLGLIPLKSFKMATYLHEKVPGINLTQDILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A1V5FYT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium ADurb.BinA280|TrEMBL
MNLSCPVSFEFFPPKTDEQRQQLDRTAEKLRSYQPRFVSVTFGAGGSTLNYTPETVRHLR
DDFGLCAAPHLSCMGGTRAEIRDLLQRYKDMGCTRIVALRGDMPSGMARPGDLRYASELV
EFIRAESGAHFHIEVGAYPETHPQAEDALADIEHFCTKMRAGADVAITQYFYNADAYFAF
VDAVRARGIDAPIIPGIMPISNFSQLRRFSEMCGAEIPRWMTRRIQAYGDDTSSIREFAS
DVVAALCRRLLEGGAPELHFYTLNLAKPTVSVLERLQD
>A0A2K2ZCW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euhalothece sp. KZN 001|TrEMBL
MAVDAQAQADSPLARLLADARFELMPFQSFTGELEELPEMAEIAVTTSPQLGIETTVEQS
VAAAAAGYRVVPHIAARYVEGPQQLRWIIDALDEAGIDDIFVPGGDREEPDGPYESALDL
LEAMEDANHPFDEVGITGYPEGHAFIDDATLRSAMAAKAPYATYIVTQLCYDAETIVEWI
DSVRDAGIDLPVEVGIPGVMNYQKLLKISTKVGVGDSVRFLRKTTGIVDTIRQVIGSRGV
YTPDALVEGLADVADDDHYDLRGLHIYTFNNTEDLEAWRQQRLAAV
>A0A537WYK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSWRFWKRRRATSLTEEQRAALKSLVADARYELIPLKSALEHAAALPPGSQVTVTASPSH
GIEATFDLAEAVAALGHDVTPHVSAHMLRDRAHLAQLLERARVNGLRKVFVVGGDTRDRG
ELHDGLMLLRAMDELGHPFEEVGVPCYPEGHPDIADERLLEVLREKQRYANAMTSQMSFN
PAAVTQWVGEVRDAGIALPMHLGVPGVADLPKLMKVAARIGVSDSARYLMKNKRLIGHLV
RGGSFGPDAFLEQLAPMLADPVADVRVLHVFTFNQVEQTAAWQRRMLEELGG
>A0A1E3M780|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPESIDKVLHFSGKARDIQDFEHFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVT
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKSVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKDKLIPTVPLETRGTSSWKNWYLTTEA
>A0A8C7HVM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus kisutch|TrEMBL
MVNQVQRVEDTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIR
NYGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVN
RRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAESL
EPPRLFLGLGVWPN
>A0A4Q4GSG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVK
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTNLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A8G1RVN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus fijiensis CBS 313.89|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKHHGDYFCVGVAAYPEGHPADNFQDSQDPARDVPYL
VEKTQAGADFIMTQLTYDIDAYTKFENMLRNHESGAFKTIPIIPGLMPLHSYKILTRVTK
LSHVKIPPHILSKLEEIKHDDDAVKRAGVDIVCDLVDGIRSIPTPGLRGFHFYTLNLEKT
VSFLLERCDLIGPYTEYDEPIEDSAAYSAARLEKPALALASRRSSVSSMPHNRVIVDKLQ
PSDVSSRESVSHEATALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHIPPAVAHKVWGYPVTRDDISALFRRHVSGELYIVPWSEGGAEEGSG
TTLNAETEIIRPELLQLIDKRGWWTLASQPAINGVRSDDPIFGWGPPGEGFVFQKPFVEF
FCPSADYHTILKPLLERHGHEKLAWFATNVRGDFESSLPGSNAEDPDPIDINPANVNAVT
WGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDATKNDVWLVCV
VGQEFGAGTEVGSKEEEEETKWMWRELAGW
>A0A7C4XWC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MASSQPVSLSFEFFPPKTPEGADKLRAVRQRLYARRPEFCSVTFGAGGSTQEGTLQTVRD
ILAEDMDAAPHLSCIGASRESVRGHLQAFAAAGVRRIVALRGDLPSGYGIGGEFHHARDL
VAFIRAEMGSAIHIEVAAYPEMHPQARSPLDDLQHFADKVRAGADSAITQYFYNAAAYRR
FVDDVRALGLDVPVVPGIMPITNSSQLLRFSEVCGAEIPRWIRLRLQSYGDDRESIRAFG
REVVASLCEELIASGAPGLHFYTLNQAEATLAVLDDLGY
>A0A401SQN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chiloscyllium punctatum|TrEMBL
MVNTEQSDKGQVFKSDSSSSDGFPESSRSSTPGPDSDRLHEKMRRRIESGDKWFSLEFFP
PRTSSGAVNLISRFDHMAVGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETLL
HITCCNQTKDELSRHLHKARNLGLKNILALRGDPMGDEWKVEEKGFNYASDLVKHIRSEF
QDYFDICVAGYPTGHPECDSYKEDLRHLKAKVDAGADFVISQLFFKPETFITFFKDCRAI
GITCPILPGIFPIQGYHSLRQLVKLSKLQVPQEIKDVIEPIKDNDAAIRNYGIDLATDMC
KVLLESGLVPGLHFYTLNREVATVEILKRLRLWTEDPRRALPWITSANPKRKVEDVRPIF
WASRQKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKNNYSKDELLKMWGEELV
DEKSIFDVFTAYISGESNSHGEKVTCLPWNDEPLALETSLMKKELEKVNRMGILTINSQP
NINARPSTDPIVGWGPEGGFVFQKAYLEFFTSSENVPILLKVLKNYKTRVNYQIVNVKGE
NINNAFDLQPIAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIERWAKLYPAGSPSR
QIVQDIHDNYYLVNLVDNDFPFENCLWQVIDDLFKLKASENTCASMTCDVTVRP
>A0A6H3SH92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLDKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKTFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A7S0G5V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosorus marinus|TrEMBL
GKPFFSFEYFPPKTDVGVENLHARIDRMASLEPLFCDITWGAAGSTATLTMDIATNIQKY
QGLDCMMHLTCTNMPAGVAKEALKEAKENGIHNILALRGDPPAGEEWKAAVDGFEHAIDL
VKF
>A0A3R9P816|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter rigui|TrEMBL
MKVTDHITRADGRTLFSFEVLPPKKGENIQTLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFTKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFQPEPDGHSYACDLIGQVADLNKGAYLDEEQDDTWATDFCIGTAGY
PEKHFESPSHATDLRYLKHKVDRGAEYIVTQMFFDNEQFFSFERRCREAGITVPIIPGLK
PITTKAQLTALPRAFYLNLPDELVDAVHLAPDNAAAREVGIEWCINQSKELMAHGVPVLH
YYSMGKSESIRRVAAALF
>W7UUE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus flavefaciens 007c|TrEMBL
MKTAELFENMTIFSLEIFPPKPDADESVIYDTLDELTDIHPDFISVTYGAGGGKNGCKTI
QIASDIKNRYGVESVAHLPCIDLTKEQARGILDSMQEHGIENILALRGDCADGSSGSGDF
HHASELISFIADNYDFNIIAACYPEIHPESRNAVEDMKWLKHKVDCGADHLISQLFLDNG
YFYDFYEKARIAGINVPVEAGIMPVTNKRQIERMVKLCGVELPRKFVRILEKYEDNETAL
REAGIAYAIDQIIDLVADDVDGIHLYTMNNPYVAHRIYEAVQSLISAKRSLQAVR
>A0A4R4WVS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea diastatica|TrEMBL
MAFELICEIEPPTKPDLKHVRHQIGTMSKVAHAFLIPDNHIGRATVSSVAVAHEVEAMGG
RGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVYGDKPASGNRTSDLTVRSMIAEAREF
SPASRLGAAAGLRPLPAWKRAADFLFLQVSFSVEAQLRWREAHPLDVPVYAGVMVLASAN
HARGLAAAIPDIALPDALVERVAADRQAGVEAACEQVLALRDSGAFDGVHLIPVSRYRDV
ERLLASSLR
>A0A4R4WJT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea diastatica|TrEMBL
MALGRPSLFPERVPTVRDMLAGGGRSFSFEFFPPKTDEGERLLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERIAHDTTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVR
GDPPGDPTAEWVPHPEGVLYAEDLVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTDYFVR
KCRAGADYAITQMFFEADDYLRLRDRVAAQGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPRLAARFEAVKDDPAAVRRLGIEHGAELCQRLLDEGAPGIHFITFNRSSATREVFQRLS
GVRLSI
>A0A397UUG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gigaspora rosea|TrEMBL
MKVKAKIQKAQEEGRPYWSFEYFPPKTQQGVQNLYDRMERMYRLGPEFIDITWNAGGTSS
QLTSEIVSTAQSVYGLETVMHLTCTNMPKEKIDKALKDAKDCGCQNILALRGDPPRGQIE
WEACENGFSYAIDLVRYIRAQYGDYFGICVAGYCEGHVDNPDKDDDLRRLKDKVDAGADF
IVTQVFYDVDLFLDWVKKCRAIGITCPIIPGLLPIQNYNGFNRIVSLSKTIVPKFVCDAL
EPIKHDDAAVKEYGIKLAVEMIKKMYNNGISGFHFYTMNLERSTRLILEALQFVAPVEKV
KPLPWCPSLSVKRKKENVRPIFWRNRIKSYVTRTEAWDEFPNGRWGDSRSPAFGELDGYG
VSLKQTKQNALELWGCPNSLNDIYNIFVRYCRGELVSLPWSDQSLAEETDIIKDQLAFIN
SLGYLTINSQPAVNGVRSDHKIFGWGPKNGYVYQKAYLEVFVSPTQLDSLIAKIERDINI
TFYAVNKQGDLKTNTQSEGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELWNEWAK
IYDPDSLSAKLITQIADNWYLINIVHNDFHDGSGIFRIFEPDCVSELVEADR
>A0A540Q009|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces ipomoeae|TrEMBL
MGAAGLRTLLHSVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLTARLAGH
GYRVVPHVPARLLRDDAHLKEVVVRLAESGVEDVFVPAGDADPPAGAYDGALPVLRRLTE
LGSPFTRVGVTGYPESHPLIHDDITVQAMWDKREHATYIVSNLCFDPRVLGEWIARVRHR
DITLPVHVGVAGPVQRAKLLSMATKIGVGESTRFLTRHASWFLRFAAPGGYSPHKLLTRA
ESALTAPSAGVAGLHLFTFNQIAETERWRRALLDRLEG
>A0A1G7FUJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epilithonimonas hungarica|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFKPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEPSVGGHKYASDLVKQIHDLGIGEYLHGKIESDTDNSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVDAGADYIVTQMFFDNQKFFEFVNQAREIGIDVPIIPGIK
PIATKTHLQMLPQVFKIDLPEALINEVIKCKTNNDVREVGIEWAINQSKELLDFGIPVLH
FYSMGKSDNILKIGREIF
>A0A2G6X008|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. 54|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYVRKPQFCSVTYGAGGSTHQGTFGAVQEILAE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFATKMKAGADSAITQYFFSPEAYFRFVDD
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TELCARLQAGGAPAIHFYTMNQSAATLAILERLD
>A0A316EGZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter polysiphoniae|TrEMBL
MKITDHIKNAKGETLFSFELIPPVKGRNIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIQHKYQVETVPHILCGGFTKEETEYVLIDCHYLGIENV
MALRGDARREQKYFEPTKGGHSFAVDLVGQINDLNHGKYLHEVIEKDEHADFCIGVAGYP
EKHLEAPSLQSDLKRLKEKVDAGADYVVTQMFFDNQKFFQFVEAARKMGITVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQNLIDAVDACADNKSVRQVGVEWAIQQSKELKEYGVPVLHY
YSMGKSDNIHAIAKEVF
>A0A1S1D4R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC065C03|TrEMBL
MTTVHPALSFELFPPRSHASCESLLHTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLRNLCQMAGMEVPTDLAYALETATSNAE
LHRIGVDYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEY
A
>Q5GUN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)|TrEMBL
MPPHHHEKTARPVISIDMPSHTRAITDAYSLEVSVKDIGALTKAAPRLLPGSSMFIPYLP
GQHDAARLAAAQLVRSLGFEPMPHLSARRIGAPEELQAFVARLVDEAGVTRCFVIAGDPS
TPKGPFADSLSLIETGVFERSGIRTIGVAGHPEGHPIMRTAEQWDVLERKCRRIQERGMA
PLIVTQFGFDADMVVTWVEALRARGIPHPVRVGVPGPASVAVLARYAASCGVGACASVLS
NYGISIGKLFGNAGPDRFVDRLASRLTDAHGDIRLHVFPFGGIGQSVAWMAQYRSRASSQ
DRMSSVHADQA
>A0A1E3BIT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus cristatus|TrEMBL
MEKLTDKIAALPPNSNYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AKRSLELAEVCQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNIHGEDDSNKDFMFAVDLVRYIRQQYGDYFCVGVAGYPEGHPADSFQDVQDPHQDLPYL
IEKTKAGADFIMTQLTYDLDAFKNYESLLRNHESGVFKTIPIIPGLMPVHSYKILTRVTK
LSHVKVPPHIAKKMEEVKHDDDAVKRVGMDVITNIVKGIMKVPSPGIRGFHFYTLNLEKT
VSFILERCNLIPDYDENAIEDEGAFNVASSTLDVAPNGSRLGSKSRASSLNSQPRNRVIV
DRKQANLEDATRDSASHEASAVSAGMPALPPNPSTTLQISEGLGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVPAPAARRLWGHPVSRSDLNTLFRRHVSGELHMVPWSEGGA
EEESGGLNAETAVIRPELLKLIDGRGWWTLASQPAVNGVRSNDPVFGWGPHNEGFVFQKP
FVEFFCPDKDFQNSLKPILEKHGHEKLAWFATNAKGDFESSLPAHPAGSDNDDLVEMNPD
NVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRVYPRGTATERFLEDTKND
VWLVCVVGQEFGAGTEVGSSEEEKEVKWMWRVLAGEE
>A0A0E3K2Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium scatologenes|TrEMBL
MFIKDTFLKNETTLSFEIFPPKNNEILFNIIGELNKFNPGFISVTYGAGGSSKDRTVEIA
SIIKNKYSIEALAHLTCITSTKEEIEEVVENLKENKIENILALRGDIPEDFTIGKEHLYR
HAKDLIHKLKIDTNLCIGAAAYPEGHNECKDLDMNVKYLKEKVDAGADFLITQLFFDNNN
FFQFKEKIYKYNIKTPIAVGIMPAVNKTLIEKIQKLSGVIIPDKVENFMNKYENKEDDLR
KAGIEYASYQIEELIKNKVEGVHFYTMNKPDIIKSILDNISFK
>A0A7D5ZNI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NEAU-sy36|TrEMBL
MTTFSFEFFPPATAAGERALWRAVRKVEALRPDFVSVTYGAGGSSRDRTVALTRRIAAET
TLRPAAHLTAVGHSVAELRHIIGSYADAGIRDVLALRGDPPGDPRGPWVPHPDGFTHAYQ
LVELLRSLGDFTIGVAAFPEGHPRSPDARSDLRHFVAKCKAGADYAITQMFFRAEDYLRL
RDRVAAAGCETPIIPEIMPATDVRQIRRFAQLSSATFPEDLAHRLEAARHDPAVAHRIGV
DHAVAMADRLLAEGAPGLHYITLNRSTAALDIHRTIRASRSLSVR
>A0A1Y6CPV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tistlia consotensis USBA 355|TrEMBL
MTRSPVISFEFFPPPEGAAEERFWQTAERLNGLAPQFCSVTYGAGGTTRDRTFGIVQGLK
ARGIEAASHLTLVGAPRHEVDAVAERLTAAGIRRIVALRGDMPNMAGGFEPHPEGYRDTA
ELVARLKRIGGFDISVGAYPETHPNAASAEADLAHLKRKLDAGAERAITQYFFDAEVFLR
FRDRARAAGITQPIVAGVLPVTNFAKLLEFSRKCGANVPAWLHERFAGLDDDPETRALVA
AHTAADLCQKLMREGVEDFHFYTLNRANLSYAVCRLLGIRPPLEEAA
>A0A3Q1NGK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos taurus|TrEMBL
MDCPKPKVFPVGHCCPSLGMRASEAGSGRLSVPPSISRNSAMVNEPRGNGSPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>A9UZU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosiga brevicollis|TrEMBL
MATFKISDRLQELSAKGEKFVSFEFFPPRTDDGVTSLMSRIQRYNDQQPLFMDMTWGAGG
STSDLTLDLCTRMVKECGANANMHLTCTNMPSEKIDIALKGARDAGIRNIVALRGDPPAG
EEAWEAVEGGYSCALDLVKHIRKEHGDFFSIAVSGYPEGHPNAITKVQDEAELTESERER
VIEMEDGLYVCRDGDFQKEMEYLKAKVDAGADLIITQMVFDAPVYGAFLKACKAYGINIP
VVPGIMCIQNAGGFKRMTAFCKSRTPAALRAAVEAAGDDKEAIRKVAVEHGAQLCRDLQA
AGAPGLHFYTLNLEKVTLAILDALNLNKVPVE
>A0A1H2GQF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. Hel1_33_78|TrEMBL
MKITEHIKKANGKTLFSFEIIPPKKGKSIQELYDNIEPLMEFKPPFIDVTTSREEYVYVE
KGGLLDRKVTRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIQNV
MALRGDAMSHQKYFEASKGGHKYAKELVTQIQNLNSGNYLHEVIEVSNKADFCIGVAGYP
EKHLESPSLQTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVAAAKNAGIDIPIIPGIKP
IAVQRHLQLLPQVFRIDLPEALIAAVESCKTSKDVRNVGIEWAIQQSRELLAAGVPVLHY
YSMGKSDNIQTIASALF
>A0A1S2P7B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces colonosanans|TrEMBL
MTTTLREVPARAAPSFSFEFFPAKTDAGMRSLWQAIRQVERLAPDFVSVTYGAGGSSRER
TVEVTKRIVAETTLRPVAHLTAVGHSVAELRHIIGRYADAGVRDVLVLRGDPPGDPNGPW
VAHPDGFQYAHELVSLVRELGDFSIGVAALCECHPRSPDWDSDVRHFVAKCRRGADYAFT
QMFFHVEDYLRLRDRVAAAGCDIPIIPEIMPATDARQIGRFAEVSGAAFPEELAHRLEAA
RGDPPQGYRIGVEYATVMAERLLAEGAPGLHYITLNRSMAAPEIHRAVSAGSHARHVLTH
AR
>A0A1R3WI03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. RU33B|TrEMBL
MSNDSRVPSADGLVPFSFEIYPPRRAEGLPALHETIRHLAASGPRFISVTFGAGGSTGGR
SLEVLTHILRETDVPPLAHLTCVGSTYPAATALIREFLDAGITSFLALRGDPPAGVSEDD
VYLGDLESAAQLVQLIQRVQAEREPYTESSLPGVPGAARVDRRQKAEVAVAAFPNGHPRS
RHPREHIDALLAKQAAGATFAITQLFFHADDYLAFVAQARSAGVVIPILPGIMPITSPGR
LQRVLELSGESLPGELAVALEVEPTPEGRREIGIAYAAALTRDVVAGGAPGIHLYAFNNH
DTVLATLREAGITTALDKETAR
>C5ZXT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter canadensis MIT 98-5491|TrEMBL
MNKIETFIETLRSHKKCFTYEFSSPASFSLEALFETIKKENLPAKIDAFVCTDSPLAKLK
HNAILASLKLQNTFEIPSITTMSMRDRNTLALQSELIGMNSLDLRLILALTGDPIRHGNQ
PQAKGIFEGNSNVLLKTICQLNTAKDINNNPIQGDFKPFYPFSVLNSYSNKKQNLYKKMQ
EKIQNGALAIFTQPIYDLEIAEELLQWSNQINQECNTHCVLIFGFFPITSYKTALFLHNK
LPGVFVPQGYLESMEKASQKGMEFEIGLQKSQELFNHLCKIHNKIHLMSANKADIIGKIL
NG
>A0A8F6TCS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia dentocariosa|TrEMBL
MTTVHPALSYELYPPRSHASCDSLLKTIAELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLALRGDIPPENTRPLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAARLAGVEMPIIPGIMPVTSLARLTKLCELAGIEVPRELAHRLETASNP
RELHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>A0A7W5ZUC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium hassiacum|TrEMBL
MNASYDQLREARTALDTPLFAGLPGDISVSFEFFPPKSDALMTQLWDVVETLAPLEPRFV
SVTYGAGGSTRDRTHGTVARIIKEAKLPAAAHLTCVDATKAEIREVAEGYWEAGVRHIVA
LRGDMGAPGVPFTPHPEGYADAAELVAGLKTIAPFEISVAAYPESHPDSPSEQADLDNLK
RKLDAGATRAISQFFFEPEIFFRYRDKLAAAGIDAPVLPGILPVSNVAQTRKFAAACGAV
IPAWMDGLFEGLDTHPGSRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPTRPALEKAA
>A0A8B5EQH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. US51|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>W5QAT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ovis aries|TrEMBL
MDRPKPKVFPVGHCCPSLGMRALEAGSGRLSVPPSISLTPPALAPCSRISAMAGSQGPRW
EGSSSGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNL
ISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSRE
EITGHLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAG
YPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVKACSEIGITCPILPGI
FPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVP
GLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIY
RTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFA
HYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDP
IVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQP
NAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNY
FLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQDERETEAL
>G0EEF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrolobus fumarii (strain DSM 11204 / 1A)|TrEMBL
MKIIVEIEPTRNISKLESLVRTITEIPCIDMVAVPDAPLGKPKVLGVMLASFFEHAGIPT
IAHVRLRDMNMVLFEQVVWGAYIAGVTRLLFLRGDPPAKGRDVNEVTSEYAVEYVKRHDK
LSSRIKAGIYLSMRWGVEKALERVMKTRADFYTVNRLDPQLSEHVEFVKKAKTTGAQIFA
YLITARSSQLEKLRAILEGQPVRPLEKLDDYIRAFRDSGVDGVVLSSPLDIRALLQILKE
TCNDA
>A0A4U7JLV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminiclostridium herbifermentans|TrEMBL
MIKDIYSSKKNVFSLEVFPPKKDDDFPVLFNALDEIKKLKLDFISITYGAGGSTSKRTLD
IASYVQNKCNIEALAHLTCVSLDECSFCKYFGELKANQINNVLALRGDRPKDMTDEAFFN
RPYKYALDLVNLIKQKSDTCIGGACYPEVHPESCNQEEDLYFLKSKVDAGIEFLLTQLFF
DNTKFYNFYEQARNHGISVPISAGIMPITAPSQIHTIVELSGASIPEELKAIFTKYENNA
DDFKKAGIEYATKQISKLLEYGVQGIHLYTLNKADVSKAIFENLGLR
>A0A401WAW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces paromomycinus|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWIQHPDGVLYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCGTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEGSPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A7Y0BT04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium olei|TrEMBL
MTKDQVLDQPLFGGLPGDIAVSFEFFPPKSEAMAAQLWETVVTLAPLAPKFVSVTYGAGG
TTRERTHATVARLVKETDLVPAAHLTCVAASKAEIDEIADQYWDAGVRHIVALRGDPPPS
DGGRFAPHPEGYRNAAELVEGLKKRHDFEISVAAYPEGHPDAVSLEADLDNLKRKLDAGA
TRAISQFFFSTDAWFRFQDKALAAGITAPILPGIMPVTNFAAIRRMSGNTEIPAWMEAMF
EGLDERPGPRGLVSAVMAADLCRRLYAGGVRDFHFYTLNRADLSYATCHLLGLRPVTGKT
A
>A0A445MR80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MPSSFKKALESGKFIVTSEVAPPKGTNLEKMRHHIELLKDKVDAMNVTDHQSSVMRFPSL
GGAILVKEMGGEPILQMTCRDRNRLALQADLLFASSRGINNVLCLTGDSVILGDHKEAKG
VFDLDSSQLLLTIRRLEKGKDLGGNDLDGGVSFCAGAIVTPEANPIEPQLIKFEKKIEAG
AEFIQTQAVYDLDNFKKFMEYASQFPVKILAGIILLTSAPMARFMNKNVAGVNVPQELID
EMAAAPKGRALEKGIEIAGRMIKRIKEEKMCDGVHIMAIGKEEVVPDIMAAAGL
>A0A009G0W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 118362|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>M4CGR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica rapa subsp. pekinensis|TrEMBL
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNAICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAYGIHFATEMCKKILAHGITTLHIYTLNVDKSAIGILMNL
GLIDESKITRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYSTLSDYQFMRPRARDKKLQQEWVVPLKGIEDVQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TLVEKSKAFSSITFMAVNKAENWVSNIGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDNDYINGDIFSVFA
>A0A1I4SV09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter zhejiangensis|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQGVRDRLASVNPDFFSVTFGAGGSTRDRTVETV
LNLHKQGISTAPHLSCVGGTRESVAELLDLYKANGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDTFNIEVAAYPEFHPQARNAEDDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMNVTIPVVPGIMPIVNFSNLVRFSDMCGADIPRWIRKQLEAYGDDADSIRK
FGEEVVTDMCRKLLEAGAPGLHFYTLNQAEPSIDIWQNLGIGEREKIAF
>A0A1I6KBE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter stanieri|TrEMBL
MKVTDHITNAKGKTLFSFEIVPPVKGRNIQELYNNIDPLMEFNPPFIDVTTSREETIYIK
KEGLLDKKTTRMRPGTVGICASIQHKYNVDTVPHVICGGFTKEETEYMLVDCHYLGIQNV
MALRGDARSEQKYFEPTDGGHPFAINLVKQIQDLNCGKYLHESIESEHCSEFCIGVAGYP
EKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEAAKNIGITVPIIPGIKP
IAVKRHMQLLPQVFRIDMPQDLIEAVDSCATNKDVRAVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAEALF
>A3XKL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leeuwenhoekiella blandensis (strain CECT 7118 / CCUG 51940 / MED217)|TrEMBL
MKITDHIKNANGKTLFSFELIPPKKGKSIQELYNNIDPLMEFKPPFIDVTTSREEFVYIE
KDGLLDKKVTRMRPGTIGICASIKHKYNVDTVPHVLCGGFTKEETEYMLVDCHYLGIHNL
MALRGDAMREEQYFKPTPGGHEYALGLVEQVAEMNKGRYLNGMVETSDCSDFCIGVAGYP
EKHLEAPSLKTDLKRLKQKVEAGADYVVTQMFFDNKKYFEFVDLVRAEGIDIPIIPGIKP
IAVKRHLQLLPQVFKIDLPQDLIDSVEACKTNADVRQVGVEWAIQQSKELMEGGAPVLHY
YSMGKSDNVKAIASELF
>A0A2J9L6M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus mirabilis|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTEEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASREELQHIAQDYWQSGIRHIVALRGD
LPDNSQKPDMYATDLVHLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMFD
GLDNDPETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPELVQA
>K0PYU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium mesoamericanum STM3625|TrEMBL
MVLNSDARRKIGISFEFFPPKSEEMEGQLWNTVSELQDWNPDFVSVTYGAGGTTKAPTLA
TVSRFIAETPLATASHLTCVGATKDETHGVIDSFRKVGVKHFVALRGDAPGGVGAPYQPH
PGGYANAAALVAGLREIGDFEISVSAYPEKHPESRDTAADIDMLKQKADNGATRALTQFF
FDNDNFERYLEKVRAAGVNIPIVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFSGFDDK
PEERAKVAAEVAAEQIEDLARRGLTDFHLYTMNRAPLVSAVLTNLGFTREGAKKAGAAA
>B1IAA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae (strain Hungary19A-6)|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A2H2I9S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis japonica|TrEMBL
XGIETEENGIVDEKPTQEAQRSWSPKHYELLHERIERLIEEKQQFFSLEFFPPRFVNGVP
NFLERVERLSEGGSVFVDMTWHMGSDPANVDKVTSSSSIAASMLDYCGVDTMLHMTCVQY
NKADTLKHLEQAKAMGLRSILALRGDLPPGTELQDTHQFRALDIIRWIREEYGDYFSIAC
AGYPLGHPQAPSYKADLQYLKAKCDAGANFVITQLFYEAETFENFVRDCREIGITKPIIP
GIMPIMAYESTIRIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTEKCIEMCKRLLGNGS
APSVHMYTMNREGSIREILKALGLWKLEGDRVFPWKNRSQHPIRCLESVRPIYWSFRPRS
YITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTVRNPDDRLGMFGAAIESFEDVKQ
VFINYITQTPNSSGIKVTVLPWTEAETGVQPETTLIRDQLVWCNENGILTVNSQPSVNGA
PSTDPLVGWGKPGGYCYQKAYLECFMTAELSDKLIQVIERDFPIRVNYHAIDKDSTFDKT
NSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVI
KSIHDEFRLVTLVDNDFQKPSVLFDVLQRALDELGN
>E1YHP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MGRWVLKFNLQGVFMSLSEKLGKSFVITTELGPVPGVMTDDSLTKAQNYLALDGINIHDC
PMGNLRINSIAMGSLIQNKLGVEAIPHFTCRDRSLLGTQADLLGAHAIGIRNILVTTGDP
PKHGPYPSKAVYDYNTFELLQLIKKMNSGLDYNDKEFGGHTDFRIVCTAMPTSRDLDHEI
ERMSKKISAGADFFQTQAVYDAKRAISFLEKAKKLNKPILIGVMPLKSVKMARFMNKNVE
GIDVPEEVIARMENDGKTGIEITCDFIKQIVDYADGIHIMAMGDIKGTNSIIEFISTLLK
K
>A2W5Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia dolosa AU0158|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAAYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCRRLLDAGVPGLHFYTLNAAAATRTICERLDV
>A0A7J9YAS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola sp|TrEMBL
MIQPIPRRRRPIAPLLAEPRYEVLPLPAVLDQTAALPPGSVVTVTASPRQGTAATIDLAE
HLAAQGMRAVPHIAARQVSDRAELAAILDRLEAAAINEVFVVGGDQPAPAGAYADGLALL
RDMAELDRLPARIGVPSYPEGHWAIDGPALWDSLRSKQDFATYTVTQLCFDADAICRFTI
EARENGVTLPVVAGVPGAVDAARLLRISMRIGIGQSIRFVRGHRSVAGRLLRPGGYRPDG
LLRKLATRMGEGRCELGGLHFYTFNRVGATARWVGQAHRRAA
>A0A832J0M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTAPRISFEFFPPQSLEASFRLWDTVQVLAPLNPNFVSVTYGAGGTTRDLTHEAVTTIHK
NYGLNVAAHLTCINSTRAEILAIADKYAAAGVTEIVALRGDPPKGADGFEPVKGGFTSSI
ELVETLAETGKFNIRVGAYPEPHPESPDTTADVEWLK
>A0A846GEF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO2B3|TrEMBL
MNRFRNAVKSGEFLVTAEVAPPKGADPTHMIEMASTLKGRVHAVNVTDGSRAVLRMSSLA
ASIILKNNGIEPICQVACRDRNRIGLQADLMGASALGLNNILALTGDPVKAGDHKKARSV
FDMESVRLLQMIAKLNQGIDWNEKALPDGATDLFVGAAVDPQSPSWSGLKKRFERKLLAG
CQFFQSQLISDFDKLEKFMNQIAVDSNKPILAGIFLLKSAKNAAFINKYVPGVDIPEHII
NRLAKAEKPLEEGIKIAAEQVQIASKICHGVHLMAIKREDLIPRILDMAEISPI
>A0A8H5TL74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium heterosporum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGTT
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALADAKALGIRNILALRGDPPRREE
YRDAEDSEDDGGQDFNWAIDLVKYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLQEHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPSHLLERLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAITVDELAIPALQINGHSNMRSSSHSRSRQSRSRRHS
SVVSDPHNYVIVGDRPAIHPEWEATSQEAGGRAEAINTRANTLAISEGEGALGREATWDD
FPNGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGHPKTRQDINDLFVKHIEGELSAIP
WSEEELLAESSTIKPRLLQLNSKGWWTVASQPAVNGLRSSDSTFGWGPPNGFVFQKSFVE
FFIPESEWNILKAKLVSSELQGYVCFYASNARGDYITSDSSDHLDGSTEASSTNAVTWGV
FPGKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGVKDEYWLVNLIHH
DFVEKDALWEVLLS
>A0A3R9PMG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanodesulfokores washburnensis|TrEMBL
MISLELNPPSRPSLDEIYEKIRRYNSFDAFIITELAMRREEDRWMDTMYTAIKLKEATGK
RIIPVMTSRESTKRGILSRILMAIHGGIDELVIVRGDQSPYGGAFGMTTVEIIRTIRSLC
ERFSKRVTVYVAANPTRDLEGEIVRAAEKLSSGADAVITQPTLDTNLLRKFIAGLRERGF
DNPVIGSIMILNSRNSAEMMERRCGIRFPEWFKEELGRGNWRDSLLTSIREIADICDGVH
ISPIAEQDFSVLLAEEARKILRDRDEQLPIFLP
>A0A6A4UPQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MSAPRISFEFFPPQSLDASFKLWETVQVLAPMAPNFVSVTYGAGGTTRKLTHEAVGAIKR
NYGLNVAAHLTCVDASRAETLEIAEAYADVGVTEIVALRGDAPKGAERFTAHKDGFASSV
ELVEALAKTGKFKLRVGAYPEPHPDAADKFADVTWLKRKIDAGATSAITQFFFEADTFFR
FRDACVKAGITAPIIPGILPIQSWDGTKKFAARCGTSVPQRLDEGFAAAKRDGREDLLAL
TQCTTLCSRLLEGGVEDLHFYTLNRPELTRDVVRALGIAPEIAPEVVLEKVA
>A0A7G8GPC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. A15-127|TrEMBL
MTTALQRTLQAGNLAITAEVMPPRGGDASHTLAMADCLKGRVHAVNVTDGSRAVMRMSSL
AVCRLLLETGLEPVLQLACRDRNRIALQGDLLGAHALGIHNLLCLTGDPVRAGDQADARP
VNEFESVKLLRQVSAFNSGEDPVQGTLADGATQLFAGCAADPQSRSWSGLQRRLQRKHDA
GARFVQTQMVMDAAALERFQRELAGPLQLPVLAGVFLLKSAKNARFINRVVPGACIPDDL
IARLEAAADPAMEGVAIAAEQVKRYLGIVQGVHLMAIKAEQRIPLILDQAGISISSLPE
>A0A1E4YAN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. YK2|TrEMBL
MSHIDENPLGVHLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLHEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRTDALVAERLHQISEGREENQQAMAEIAA
HHTPPQAH
>A0A357FAV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTPLEISFEFFPPKNLEASFRLWDTVQVLAPLEPRFISVTYGAGGTTRDLTRDAVSALHK
SSGLRVAAHLTCVNSSRKETLAVAQSFAAAGISDIVALRGDPPKGEGSFTPHPEGFQSSL
ELISALAQSGDFTLRVAAYPEGHPEAESTSTDIDFLKRKIDAGASEALTQFFFEAETFLR
FRDACDKAGIKVPITPGILPIENWQGTRRFAKACNAKVPNWLTDAFSKAERDDREDLLAT
AVCTELCSQLIDEGVDALHFYTLNRPDLTRDICHALGITAAVKLEKIA
>A0A6C1T0T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
CAREGITGKIIPGIIPIENWSGIRKFALATGASVPQWLDDAFEKAARDGREDLLATALCT
EMCDRLVREGVEDLHFYTLNRAHLTRDVCHALGVVPQVALEKVA
>A0A1H4LV89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces melanosporofaciens|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRADLRNIIGQYADAGIRNMLALR
GDPPGDPTGEWVRHPDGLNYAVELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATEVCARLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>A0A2E8PBK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MKAGSAFASRAAGAAPKEPIRGVALVTDPSGRSLSISFEFFPPATPNGAMRLWRSVERLA
PLAPSFVSVTYGAGGTTRDRTRNAIKAILERARLQVAGHLTCVGATREETLEEADGYRKL
GARRVVALRGDPPKGADRFEPHPDGFRNAAELVTGLRAAGHDRISVAAYPERHPDSADLA
EDLDNLKRKLDAGADSALTQFFFDNDLFLRFRDAAAKAGITAPIHPGILPIENFGKMRRF
AAGCGATIPDWLVTAYGNADEQGMTETLSRAICAEQCDGLLAEGVEHIHFYTLNNPDLPY
DVCRAIGVEPQPLGAAAAGGA
>A0A1X7PGD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium australicum|TrEMBL
MSQFRLSRRPDIGDKVRVSFEFFPPKSDDMEARLWDTVKRLEPLRPSFVSVTYGAGGSTR
ERTARTVRRILTETSLSPAAHLTCVDASREQSDAVIADFLTMGVKRFVALRGDPAEGVGS
HYRPHPHGYSNGAELVAALAAQGAQDISVSAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDVYERYVERARRAGIYIPIVPGILPVHSFTAVANFASRCGAHVPAWLAERFD
GLQGDPQTHALVAAAVAAEQVLDLVERGVGDFHFYTMNRADLAFAICHMIGIRATEEVPM
VSASAA
>A0A3M8G562|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneola sp|TrEMBL
MKVTDYFNQANGETLFTFEVLPPLKGQNIRTLFDHIDPLMEFNPPFIDVTYHREEYSYKK
HSNGLLERKTVRKRPGTVGMCAAIQNHYNVDAVPHIICGGFTREETENALIDLNFLGIDN
VLVLQGDVRKPDREFIPEENGHAYASELLGQVVEMNNGIYLDDEIENAQPSNFCIGVAGY
PEKHTNAPNMESDLRYLKKKVEGGADYIVTQMFFDNQKYFDFVKSCRAIGIEVPIVPGLK
PITTLKQITLLPDLFHIDIPEPLTNELEKCKDNESAREVGIEWAIKQSKELIEFGVPTLH
YYSMGKSLSVYEVAKEVF
>A0A8J2ZKW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger pallidus|TrEMBL
MNRPEISFEFFPPRNIEATFRLWDTMQTLSPLAPRFVSVTYGAGGTTRELTRDVVATLHK
HSGLPVAAHLTCVNATREETLGIAKQFREAGVRDIVALRGDPPKGSDGFVPHEDGFKSSV
ELIEALRETGDFNIRVGAYPDIHPEAPSATSDVEYLKRKFDAGASEALTQFFFEADSFFR
FRDACEKAGIDKPIVPGILPIENWKGARRFAEATGTKIPAWVIEAFEAAERDGRTDLLAT
AICTELCTELLEGGVDKLHFYTLNRPELTRDVCHALGVTPEVSLENVA
>A0A1M7BZ35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga jiangningensis|TrEMBL
MQDLLKTKLVEGQSGIVLYSLTPPKITTEEERVTAIAYNQVERLKNLDIDGLILYDIQDE
SLRTEKERTFSFIPTIAPEQYSKQFLADLSVPKIIYKSIANQTKETFSNWLEQNEDLQYS
VFVGASSHQQVAATQFSLSDAYDLKKASGRDFILGGVTIPERHNKKGDEHLRIFNKMDQG
CNFFVSQCVYNLHDTKNLLSDYYYNSVESGKQIAPVIFTLAPCGSLKTLQFMEWLGIEVP
KWLYNDLKNSKDILKASLDTTTNIAAEILNYAQAKNMPVGFNIESVSIKKEEINAAQELL
HNILDLTKEIRKPKKAARPAPAY
>A0A0D7ARE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fistulina hepatica ATCC 64428|TrEMBL
MKISEKIQQSTQDDRVWWSFEYFPPRTAQGLQNLMDRIERMRNLGPEFIDITWNAGGRTS
ELSSEMVKTCQGLIGIETCMHLTCTNMPRDKVDIALRNAKAHGCMNILALRGDPPSGKEE
WEAVEGGFAHGIDLVRHIRKHYGDYFDIAVAGFPQHMLLPPEECAMEIRYLKEKIEAGVN
FIFTQMFYDVQLFIDWVREIRAAGITVPIIPGIAPIQTWNGFHRATSLAKTVIPRHFLEV
LGPYKNNDEKVRALGTKLVADMCRRILSEDIGIRGLHFYTMNLEKATKMLLEELQLVPRR
ETVKPLPWRQSLTPNRRSENIRPIFWSNRTKSYISRTENWDEYPNGRFGDARSPAYGELD
GYGVWIKQTKEDALRLWGQPKTFRDISSLFARFCVGNLDALPWSDEKANPETSVISQQLA
KLNELGFLTINSQPAVNGASSSDPLFGWGPSNGYVYQKAYLEFFVNPALLSLLLSYIELD
TQITYYVINKSGDLRTNTRSDGPNAVTWGVFPGKEVVQPTIVEAVSFMAWKDEAYELGEQ
WAKLYEAGSVSGKLIHDLMNSSYLVNVVHNDFHKRDAIFEPFYKAGAEFAAKTKATAAEH
>A0A2U3JVW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacter sp. SbD1|TrEMBL
MRMKEKLLSGEFVLLAEMDPPKGTDISEMVANAIRVKGKVDAFVIPEMSNAVMKMSSLGG
CMLLQGKGLDTVMQTCCRDRNRLALQADLLAANALGISIVIAITGEEPSFGDHHRARAVH
DVDLLELLDGIKKLKSGRDMAGVELKGTPSFCVGSVVNAGASGGALDIEIEDMERKIEAG
AEFFITPPVFDLQHLGRFMKRVAAHSPRIIPTVMLLKSVGMARYIQRHREHVHIPEDLIR
RIQQAPDKARECVRIAAELVSEIKEAGYSGVLVSTIGWEDKLPGILGE
>A0A0B1P9I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Uncinula necator|TrEMBL
MHISDKLAEAEKSGHPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGNIA
QLTVEMVGVAQSYYGLETCMHLTCTDMGKEKVDNALKGAYGAGCTNILALRGDPPRQQEK
WTAADGGFHYAKDLVKYIRQKYGDYFDIGVAGYPEGCDDQDDPELLLDHLKEKIDAGGTF
IVTQMFYDGSNFLEWVSKVRAKGISVPIIPGIMPINTYASFIRRANHMGCKIPPKWAKAL
QDVKNDDAAVRSIGTVLVAELCRNILASGLIHHLHFYTMNLAQATKMVLDELNLTPSEGR
PLKHPLPWRQSLSPRRREEDVRPIFWKNRNKSYIMRTQDWDEFPNGRWGDSRSPAFGELD
AYGIGLKGSSEQYRKLWGEPTSIKDIAEIFVKYLQGGVDSFPWGETPITCEADCIKSELI
DLNQRGFLTINSQPAIDGVKSSDPVFGWGPPNGYVYQKAYLEVLVPNELIHEIISRVCRE
PDLTYHAVNMAGNLMTNTPSDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEAYRLGLD
WARCFPASSLSSQLIENVMKNWYLVNIVHNDFHETLGLYRVFEGLKVSNFDNPFDATKSL
NPTTNGNSSIQNGKITNGYSIHNELKLNGCDNDNKN
>A0A1V0PT53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum sp. P5|TrEMBL
MSAPRVSFEFFPPKSIEASFNLWDAVRGLAPLKPEFVSVTYGAGGTTRKLTHDAVETIHK
HYGLNVAAHLTCVEASRAETMEIVESYAEVGVTEIVALRGDPPKGEGKFTPHAEGFQSSC
ELVAALAETGKFKIRVGAYPDPHPESKGAGDDVRWLKKKFEAGAHSAITQFFFEADTFFR
FRDACEKEGIDGSKIIPGILPIEKWGGVRKFAKNCGAHVPAWVDEAFEKAIRDDREGLLG
KAMATELCTELMKGGVEDFHFYTLNKSYLTRDICHALGVQSAAQLEEVA
>A0A3D0W7F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas bacterium|TrEMBL
MPAVVTDGYSLEMTAKDFDALHEAAPGIAPETPVAIAFLPGETIDARVAAAAAVRRLGFE
PMPHLSARRIGALGELDTMLGRAVDEAGARRAFIVAGDPPEPAGPFADTLSIIRTGLLEK
HGFRAVGVAGHPEGHPNMAGEALWDALVAKLDALEERGLGSLIVTQFGFDADPFIDWLTE
LRARGIMAPVRIGVPGPAGIKTLLRFAARCGVGASAAVMTKYGVSITQLLGKAGPDRLVD
ALVARLTPAHGPVRLHFYPFGGLVNTVEWINGYPARTR
>A0A0S2G2M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter gummosus|TrEMBL
MLPISFEFYPPKTDDQRSQLDKTAAKLKPYTPHYVSCTFGAGGSTLSYTPETIRRLRQKH
KLDAAPHLSCVGGTRVEIRELLALYRDIGCKRLVTLRGDLPSGMASAGDLRYANELVEFI
RAETGDHFHIEVAAYPETHPQARDAHSDLENFKRKVRAGANGAITQYFYNPDAYFRFVDD
VRASGIDIPIVPGIMPIANFSQLRRFSDMCGAEIPRWIAQRMHAYGDDADSIREFGADVV
AQLCSRLIEGGAPGLHFYTLNLAKPTLTVLSRIA
>A0A0D7AG35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fistulina hepatica ATCC 64428|TrEMBL
MKWAQKIRDHNGPQPFFTFEFFPPRTDQGFENLAPRVARLAALNPLGVSVTWGAGGSTKQ
RTLDLVGIAQEDYGLDTLMHLTCTNMKRGLVDEALAAAKQHGIQSILALRGDPPRGQEEW
MPTDSRFTHGIDLVTYIRESQWADDFCVGVAAYPDGHSDYTVDEETEIVLLKEKVDAGAE
FIVTQLFYDVNRFLSWVGKVRAAGISVPIIPSIMPIQTYSSFLRMTKLCGTRVPESVTVA
LKTIQHDDALVKDYGVKLAIETIRRVTTEGAIPGVHLCTLNLEKSVQRVLEGLQWTGAPP
SLKNKLIADAEQVSTNGTGLVVTPGTASTDATLGLVRVPSNKTGAAGHGELNNATSWDEF
PNGRFGDAKSPAYGDLGPWGSLPAGVQQDAHLGHPRTKADLTNIFLAYLEGRIPTTPFSP
LALSEESKLILPHLAALTRRGWWTVGSQPAVDCTPADDPVVGWGPRNGYVFQKAFVEFFC
EEADVRWLERHVRARAQGWIDWIAADVHGRFESNLVADARNAVTWGVFPGQEIVQTTIIE
RESFESWKTEAFSIWSEWASHYKPDSEERKLLEGVRDRRWLVSIVHHDYKKPNALWTFLL
SDTAQEQP
>H0QL93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter globiformis NBRC 12137|TrEMBL
MSPPSLIDTHPNLSDTAPVALSYELFPPRSPAAAETLWTTIRELEATDPDYVSVTYGASG
SNRDTAVELINRLVLETTLRPLAHLTCVGNTPTELAEIIGELLDAGVRGILALRGDLPKD
SGEPVSGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHRDQYADLLTRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAPELIERLAAADTDAERLQIGVSATVDLANAALDAGAPGLHIYTFNEHQSALEVLDKMS
LGRPARSSSRLTALARRQLAS
>A0A4Y8Z6Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 1R11|TrEMBL
MSEDSVRGRSSRGFVTRTPSIVDRLRTEPEARIPFSVEFSPPRDEAAEARLWRAVREFEQ
LQPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSVAELRSMVGSYADRG
ITNILVLRGDPPGDPLGEWEKHPEGVEYAEELVRMVRELGDFHVGVASFPEGHHRADDLE
QDTRCLVGKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSV
RRMLELSGTTLPSHLDEKFTRAAGSGAEEDKAAVREVGIELATNIGERLIAEGAPGLHFI
TLNFARATREVLSNLGLAAARV
>A0A101QXT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces longwoodensis|TrEMBL
MDVVAPLPRPAAGDLLDGYSLEMTGKDVAALEAARPAIPDGTRVNVTFLGTEDTELRLAA
VRAVRRLGLVPVPHLSARRLRSRAELEAFLSALRDAGAADHVFVVGGDPSVPLGPYDDAL
AVLRSGLLQEYGVRHVGVSGYPEGHPAISEPALWSAIEEKAAVLREEGLTGSVITQFGFD
PEPVLAWLEAVRDRGVDLPVRVGVPGPAGIRRLLRYAARFGVGTSAGIAKKYGFSLTNLM
GTAGPDRFVHALAERHDPGRHGELGLHFYTFGGIGATSDWAAAFRTGAQVPAPAPATA
>A0A1C7DL02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus antarcticus DSM 14505|TrEMBL
MGLLDELKTKILTADGGMGTLLYSYGIEYCNEELNLQRPEIIEKIHQDYITAGADIIQTN
TYGANAFKLARYGLEEQVADINKAAIEIAKRAAAPGGQFVFGTIGGIRGIRKSDATLQEI
IAMVDQQASHLLAGNPDGLLLETYYDFEELAATVKQLKGITDTPLIAQVSMHDPGILQNG
MSLNDALHQLEALGADIVGVNCRLGPHHTIQAFEEVTLPETAFLSAYPNASLLDVEDGRI
VYESEADYFGRAALLLREEGVRLIGGCCGTTPKHIEAVKKHLGNLPPIFHKEVTARKPIV
IREAEALEVKPLHEKAKTERTIIVELDTPRHLDITKFMEGSVALNEAGVDAVTMADNSLA
SPRISNMAMGSILKHTENIRPLAHITCRDRNLIGLQSHLMGLDALGMHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIESGADYFISQPVYTKEKIIEIHEATKHLETPIFIGVMPLTSIRSAEFLHNEVPGI
KLSDDALERMRTCGEDKDRATVEGIQIAKELIDTAAELFHGIYLITPFVRYDMTVELIRY
IRQLDQQKESDRSHAQTSY
>A0A2U3K0H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfotelmatobacter kueseliae|TrEMBL
MAADFLARLKQSTVLCDGAMGTLLYAKGVFINRCYDELNLSQPDLIRGVHHEYLQAGAEI
IETNTFGANVFRLARHSLADKVVDINRAGARLAREAAKSFDVWVAGSVGPLGTRIEPLGK
TSFQEARDAFRQQIEALVQGGVDLLILETFGYLEEIHQAMLAARDVNPALPIVAQVTIDE
DGNCLDGSDPGTFGPKLAEWGADVIGCNCSVGPVAMLDAIERVRAATSLPLSAQPNAGVP
RSVEGRNIYLCSPEYMASYARKFVAAGVRVVGGCCGTTPDHIRAMKSALRVGEARGKSTL
APAASGPAAAKAVPAVPLGNRSALGSKLARGEFATMVEIVPPKGTDIRKEVEGARFLKSV
GVDAVNIPDSPRASARMSNQALSLLIQREVGIEAVLHYTCRDRNVLGIQSDLLGAAAVGI
RNLICITGDPPKMGNYPDATAVFDVDAIGLVNIVHNLNRGLDIGGNPIGTGTGFVIGVGA
NPGLTDLDEEIRRFEYKVEAGAEYAVTQPVFDLRLLENFVRSIEHCRIPVVAGIWPLVSV
RNAEFMKNELRVSVPDSILERMARAQSPEAAREEGVAIAREMLIAVRQIVQGAQISAPLG
RYSSAVDVLEALGVRGPTASV
>A0A2M7NSS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG_4_10_14_3_um_filter_49_12_50_7|TrEMBL
IDYASAQCEDLLRNGVRFFHFFVMNRAESSACIIENAGIV
>A0A076F8Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter iguaniorum|TrEMBL
MLKDKIESNTPGILLYGITPPKINLSKEEAEEIANKQLERLKDSKFDGLVIYDLQDESNR
NSSERTFEFICTIKPEIYHKEFLHSAYPAVIYKAVGNYDEAEFREFLQSSSSDTLSVFVG
ASSKQDKQKLALNDAYKLKNECGQGVTLGGICIPERHIKKGDEDLRVAGKSIKGCKFFIT
QAVYNIENAKRFIDDYANLGVKKVPIIFTFTPCGSSKTLEFMKWLGIAVPEYFEDRLFSS
QNALESSVSLSLDMFEFLFKYAKAKGISVGANVESISTRKVEIEASINLLNGIQKIIEDE
KELSYREIWQSASKMTE
>A0A0C2YCC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum magnetotacticum MS-1|TrEMBL
MSLPRSELPIAAASRKPVSVSFEFFPPKTEKMQVSLWECVQRLAPLAPQFVSVTYGAGGT
TRERTHETVVRIARETNLKPAAHLTCVGHAKGEVDDIARRYWDEGIRHIVALRGDMPDGQ
AYAAHPQGYAYAADLVAGLKRIADFEISVAAYPEKHPDAPSADFDLDNLKRKIDAGANRA
ISQYFFDPAVFLSFRERAAKAGITVPILPGILPVTNFAQVQKFSAACGASIPGWMADLFE
GLDDDPETRRLVAATMAAEQCRILAAEGVEQFHFYTLNRADLAYAISHILGVRPKG
>R6SQC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus ruminis CAG:367|TrEMBL
MGQTTFSFEIFPPNKESAVEKLTETLDELVGLSPDFISVTCTNKNDDLARLTVKLAGYVK
NKLDVPSIAHLPAAYLDKQQVSEILNELETLGVTNLLALRGDRIEGRKPKDDFRHASDLI
AYVHENFPEFHISAACYPEIHPESNSRVDDIKHLKYKTDQGVDSLITQMFFDNESFYGFK
ECCELADINAPIVAGIMPIVKRNQALRILKTSSATLPKKFTAILNKYRDDPESLRAAGLA
YAIDQIVDLVTQGVAGIHLYTMNDAETAKYIWQATSSLFENGRKVHQV
>A0A1H5S5W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella ruminicola|TrEMBL
MSVTEFIHQDKSCRRFSIEVLPPLKGTGTEKLFADIDKMLELNPAYINITTHHSEYVYKE
LDNGQFERQRIRRRPGTVAIAAAIQQRYNIPVQPHVICSGSTIEEIEYELLDLQFLGISD
VLLLRGDKAKEDSRFVPTPGGHAHTTELMKQVKRFNEGFFADGTPIKRPGKPFAYGVACY
PEKHEEAPNLEMDMQYLKEKQELGAQYAVTQLFYDNEKYFAFVEKARQMGITIPIIPGIK
PFAKLAQLTVVPKTFHCDIPEALAKEVVKCKTDEDARQLGIEWTTAQCKELYGHGVNNIH
FYTVSAVDSVIEVAKRL
>A0A2U1RQ16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division NC10 bacterium|TrEMBL
MKIADLYGHGRFGLSFEIFPPKTEAGEVQLFSALNTLMVYRPSFVSCTYGAAGSTRDQTL
ELTVKIRERCGVTTAAHRTCVGSTVEEIRRWLKEATDRSVENIVALRGDPPKGEVGFTRP
EGGLGYANELVALIRQEFPYFSMAVAGYPETHQEAPSPAVDLANLKRKVNAGADAVITQL
FYDNRDFFDFRRRYREAGIAAPLIPGILPVINLGQIQRITSMCGAKIPAAFLAELDGCRD
DPAGQVSVGVQYAIRQCRELLDAGIPGLHFYLLNKAEATLQILQALDLPR
>A0A5R8V4R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glutamicibacter sp. V16R2B1|TrEMBL
MPGSVAPPSLSYELYPPVNREVAESVYHSIEQLADTSPDYVSVTYSGTPARRAQSLALIE
HLVTQTKLRPLAHLTCVGESAQSLRVLIRHFIALGVRGVLALRGDLPQDPQGWRGEFPFA
RYLIELIRQVEDEHAASLAGGRLGVGVAAYPHRHPESPSFEHDIEVLLGKQRSGADYAIT
QVYFQPEDYRGLLAAARRAGVCIPIIPGIIPLNSLRRLNRLAALTGVQPDPILAHALQSA
TSDAERHRIGVRWAVDLARAAFDDGAPGLHLYTFNDHRGSLDVIEQLQLPGARSTLAQSW
AAHSGA
>A0A6L4ZAK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prolixibacteraceae bacterium|TrEMBL
MKILDIIKNSKSTVFSFELLPPLKGNDAGKIYQTIESLTDFDPKYINITTHRDELEFKEM
PDGTIVKRTVRKRPGTVAIAAAIQQKYGIPVVPHILCGGFTKSETEHVLIDLNFLGINNV
LALRGDGVKNQHVFVPTPNGHSNANELVLQLKDLGKGKYLEEDLKNNTPLDFCIGVAGYP
EKHFEAPNMEQDLLYLKQKVDAGADYIVTQMFFDNKIYYDFVKRCREIGINIPIIPGIKP
ISLLNQLTVLPKLFSIDIPVELAKELGKCKTNHEAARVGTEWAIYQSKDLVANNVPSLHI
YTYGVADNVKEIVKAVF
>A0A8H4FLN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum gloeosporioides|TrEMBL
MHIKAMLDETRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREHEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDADNFIRWVGKVRERGITIPIIPGIMPIATYASFLRRAKHMNCRVPDDWMAAL
EPVKNDDVAVREIGKGLVANMCRKIIAAGIHHLHFYTMNLAQATRMVLEELDYMPSSERP
LKHALPWKQSLGLGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSIKDVANIFVRYLETEIDNLPWSEAPLTSEADGIREELIG
LNKRGLLTINSQPAVDGVKSSHPVHGWGPPNGYVYQKAYLELLVHPELFPEIVARIEKNP
DMTYYATTKNGALTYNASSDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGTDW
ARCFEAGTPSRVLIDRIMNEWYLINIVNNDFHQKTALFDLLDGLSVQEYTDIPSEPQANG
ETELQNGTTGAAVTA
>A0A374AWR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerostipes sp. AF04-45|TrEMBL
MKISELLKEKATISFEVFPPKNKEGDISSIYYTIEELAKLDPDFISVTYGAGGSSKGKTV
EIASAIKNKYQIESVAHLSCITSTKEDILTECRALKEHNVDNILSLRGDYPAGEEEKYRG
MDLEFHYASELNGFIRENFGDSFCLSGACYPEVHQEADCFRDDLEALKKKVDAGAEYLIT
QIFFDNSYYYRLVKEARKIGIDVPILAGIMPVTNAKSLLRTAKLCGCSIPFQLSTMIETY
YNYPEAMKEIGINYAAHQIIDLITNGVDGIHIYTMNKPEIAQRIFGNIPTVLKELNHD
>L1KL03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces ipomoeae 91-03|TrEMBL
MRDMLATGKTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSVTYGAGGSTRAGTVRA
TEQIAADTTLTPVAHLTAVSQSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVPHP
QGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSPDWDSDVARFVDKCRAGADYAITQMFF
HPESYLRLRDAVAAAGCETPVIPEVMPVTSVKMLERLPKLSNAAIPDDLKERIVTAKDNP
AAVRSIGIEFATEFCRRLLDEGVPGLHFITLNNSTATLEIYENLGLHDSPRA
>A0A2S7FIU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas oleovorans|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLAAYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEVAAYPEMHPQARNFESDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSDSIRAFG
EQVITEMCERLLQGGAPGLHFYSMNLAAPSLAIWNNLKLSR
>A0A080LTU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter sp. BA-91|TrEMBL
MTPQTPVFSLELFPPQTPEGVEKLRAARARLALLKPRFFSVTFGAGGSTRDRTLDTVLEI
QREGQQAAPHLSCIGSTRDSIRSILEQYRAHGIRHLVALRGDLPSGMARPGTFRYANELV
EFIRAETGAWFHIEVAAYPEYHPQAKSPMDDLLAFKRKLEAGADSAITQYFYNFDAYAHF
IDECQAVGIHVPIVPGIMPISSYSSLARFSDNCGAEIPRWVRKRLESYGDDTLSIRAFGL
DVVTALCEKLLAGGAPGLHFYTLNQVELTTTLWQRLGLSRAMSGS
>A0A3R6J172|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. AM08-6|TrEMBL
MKVIDLIRGSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEYIYKTL
PDGSFQKINIRKRPGSVAIASAIQNKYGITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQNTNLYHEHATDLQQQVNNFNNGIAVDGSVFDANETSFSYGMACYPE
KHEEAPNMESDIYYLKEKVKNGADYLVTQMFFDNEKYYSFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDEEAKAVGVEWCIQQCKDLIAHNVPSLHFY
TMMASDSVYKVAKEIY
>A0A2S9CT67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium culicis|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTHGGHASAMDLVNQINNLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELISEVENAKNNEAVKQIGIEWSIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A5C6C3M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium Poly21|TrEMBL
MTLADQYRSDGCAISFELFPPKTSDGIDSLCENVERLMQFQPRFFTCTYGAGGSSQGTTL
EVLQRVKQLTNLPVASHLTCVGSSTQQLCEYLRQATEMGIDYIVALRGDPPKGTTEFSVT
EGGLRYANELVDLIRQNFPNLGVAVAGYPEVHQEAIDAQTDLGNLKRKVDAGADIVITQL
FYENSDFYRFRDDCSRAGINVPIVPGILPVTNFKQAQKIAGMCKAAIPNQLAEAMMKNDS
AEHQFRVGVEHARQQTIDLMDNGVPGIHYYVLNRSAAAAELLDGLQMAGT
>B7UNR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O127:H6 (strain E2348/69 / EPEC)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPLGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3D0G988|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritimibacter sp|TrEMBL
MKPPRISFEFFPPKNVNSTFRLSDTVRDLAPLDPSFVSVTYGAGGTTRELTHDVVSTIHR
NYGLNVAAHLTCVNASRAETMDIVDRYVASGVTDIVALRGDAPKGTDRFAATPDGFANSV
ELVEALAKRGDVNIRVGAYPDRHPEARDENADVEWLKRKIDAGADSAITQFFFEAETFFR
FRDKCAAAGIDAPIIPGILPIETWSGVRKFAQSCGTPVPVWLDEAYERAERDGREDLLSI
SLATELCTELVEGGVEDLHFYTLNKPGLTRDVVHALGVTPRVALQNVA
>A0A2G6IR87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium|TrEMBL
MSAPTVSFEFFPPRNLQGAFRLWDTVQTLASQEPCFVSVTYGAGDTTRDMYHALGATPRI
QMENVA
>A0A1F8LRW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_46_14|TrEMBL
MANSLFEEKLNSGEFIITTEIGPPKGVDLTEMIHHIDLLKDKVDAINITDHQSSVMRYPS
LGGCLLVKEHGGEPIFQMTCRDRNRLALQADLMFAYSRNVVNVLCLTGDSVDVGDHKEAK
PVFDADSVQLLEIIKTLESGYDTAGNELNKAPQFFAGASVHPEADFIEPQLIKFDKKVSA
GARFFQTQGIFDLASFRRFMQYASRFNVKILAGIIVLSSAGAARYMNKNVPGILVAQEII
DELASVEKGKGLEKGMEIAARFIRKIREEKLCDGVHIMAVGNEHIVPEIIEASSAVSVPS
R
>A0A2A9YD34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia megaterium|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINVAGVKLAKQAAKDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLNEGVDGLLFETYYDFEELKTVLTLARKETDKPIITHVSLHDIGVLQDGR
PLADALKELEALGADVVGLNCRLGPYHMIQSLEEVPLPDCSFLSAYPNASLPAYVEGKLE
YETNEDYFVESARLFREQGVRLIGGCCGTTPAHVRAMSSALKDLPPITSKVVKMRPAVTV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRIRGEVEGLAIAKNLIDTAYELFDGIYLITPFMRYEMTEILTRYI
HDKQLVTSERKI
>A0A7L6Z8D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. RHB20-C15|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGSGKPDMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGI
>A0A8J6NKF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfolinea nitratireducens|TrEMBL
MKLTDIWKSRNEPTISFELFPARTEKAAANLEKAIEELAALEPDFVSVTFGAGGSTREGS
RQLVKKLKEEKGLEVIAYFAGFGLAPDKITAVIDDYQALGVENILVVRGDEPRDENFTPH
PESFSYASELMGYIRPRYDLCLGVAGYPESHIDAASQAKDMEYLKLKVERGAEYIICNYF
YDNQYFFDYLARCRAAGIDIPIIPGVMPIYNIKMMRMLAGMCGATITETIETGIAALPED
DAAALNDFGIDFAARQSAELIEAGVPGLHIYTMDRSKSTLGLVNRLREDGLL
>A0A4Q4U7P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus sp. GIB2|TrEMBL
MQIQEMIADAERTGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYFGLETCMHLTCTDMGEEKVNDALARAYKAGCTNILALRGDPPREKEK
WVATEEKFQYARDLVAHIRQKYGNHFGIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGATF
IVTQMFYDADNFIRWMTKVRERGINVPILPGIMPIATYASFLRRANHMNCKIPESWMTAL
EPVKNDDAAVRDVGKTLVAELCRKIMAAGIVHLHFYTMNLAQATRMVLEELDWLPTTTRP
RKQALPWKQSLGLRRREEDVRPIFWRNRNKSYVSRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKKWGEPKCIKDIATLFVRYIEKDLQTLPWSEAPLTAEADSIRDDLIK
LNQRGLLTINSQPAVNGIKSSHPVHGWGPPNGYVYQKAYLELLVPPELFPEIVSRIHNHP
DLTYYAVTRTGALKTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAYRLGKDW
AHCYDPNSPSRVLIDKIMDEWYLVNIVNNDFHQPRTIFELFEGLHVDNLDVYNTPDSNGV
HNESNGDTGLANGSGRAAAT
>A0A3B9T2W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKAISLFEKKPVLSFEVFPPKPDVPIESIYRTLDALKELHPDFISVTYGAGGSVPGASTA
EICETIQNRHGIPSIAHLPCINETKESVLEKLRIFQEKGIENILALRGDRNPHAAPKDDF
RYAVDLISFIRAHGDFDIAAACYPEGHPEAADLETDLAHLKEKVDAGASHLISQLFFYNP
DFYAFREKLVQKGIHVPAEAGIMPVTSKKSIERMVSLCGASIPKRLAKLMARYADDPASL
KAAGLEYAIMQITDLLENGADGIHIYTMNNPDVARYIMEQIAEDIPR
>A0A1Z5IAN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Secundilactobacillus mixtipabuli|TrEMBL
MKVVDCFKERPVISFEIFPPRPNASEKAIERFYDNLDVLASLKPAYISVTYGAGGSDNKS
GTLALCCYIKQHYGIEVVPHIPGINFTKSAVKAYLADLKAADIENILALRGDLPADGKSQ
GDFQYASDLVSEIKRDGDFNILGACYPDVHPEAKDSVEDIKNLKCKIHAGVSQLITQLFF
ENEHYYQFLERCELAGIDVPVQAGIMSVVNERQIRRMATMNGVGLPPKFLRMMNHYQDNP
IAMRDAGTAYAIDQIVDLLSEGVDGIHLYTMDNPVVTQRICGAIETLI
>A0A2M7DZ43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium CG02_land_8_20_14_3_00_31_25|TrEMBL
MKVAEILQNTKKTLISFEILPPLKGDSIEGIYKTIEPLLEFKPPFLNVTYHREEVVYKKH
SNGLLERRIVRKRPGTVAISAALHYKYGIEVVPHIICGGFSREETENALLELHFLGIRNV
LIIRGDPDKSLREFVPEEGGNAHAIDLVKQVMNLNKGIYLDDELLNSTKTCFSVGVAGYP
EKHPEAPNMKSDLAYLKNKIDAGAEYIVTQMFFDNKKFFDFVAQCRKIGITVPIVPGIKS
VSVLSHINILPKTFYIEIPEALEREAKKCKTNDEIKQVGIEWAVAQSKELIAAGVPVIHY
YTMGKSDNTRKIVEAVF
>A0A4Q9KGQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevilactibacter sinopodophylli|TrEMBL
MPETIVDRLRASDGPTFSVEFFPPSDDAGVQQLIGTVDALGGLRPDWLSVTYGATGASRY
KTFSAVGAIRGTTDTPLIGHLTVAGQPLGEIRRALDAYARLGVTHVLALRGDPPGGGAFV
PHPDGFINATELVRFIKGYGDFTVGVAAFANAHPEGSAELDARILLDKQEAGAEFAVSQM
FFDPQAYVSMLGRFRSLGGTMPVVAGIMPITVPSQIERFGAMSGAELPRDVVGPLLAVAD
SKEKFREVGVDLITQLCRDVLDAGAPGLQFFTLNRSTATVEILGRLRDPGVARAS
>A0A1E7JCL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium C00003063|TrEMBL
MKTESNLEKVLAAGHLAVTSECGPPRGAVAKELTDKAKYLEGVVDAVNVTDNQTAMVRMS
SLAGSVLIKQQGMHPLLQVVTRDRNRLAIQADILGAYSLGIDTMLCLSGDHTKFGDHPMA
ANVHDIDSIQLIQMVKGMRDESKFQGGSDIKGAPKMFIGAAANPFADPFELRVMRLAKKI
AAGVDFIQTQCIFNIEKFELWMEGVRKMGLHKKCYILAGVTPMKSVGAARYMKNRVPGMD
VPADVVERMASVPKEKQPDEGVDICIETIERLKKVEGVAGFHIMAIEWEEKVEEIVRRAG
LYPRPEIS
>A0A433KPF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas andesensis|TrEMBL
MINHDTGDGRRATLASAYSSNSRLERVLKAGYFAVTSELAPPDSANPEDVYARARVFDGY
VDSMNATDGSGANCHMSSVAMCALLSRVGYDTVMQISCRDRNRIAIQGDVLGAAALGVNN
ILCLTGDGVQVGDHPEAKPVFDLDSMSLLDVIVGLRDKKTFVSGRKISDPPRVFLGAAEN
PFVPPQDFRPYRLAKKIAAGAQFIQTQYCFDLPQFETFMARSRDLGLLEKCFILPGVGPL
ASARAANWMRSHVPGVHIPDAVIKRLEGAQDQKEEGRQICIEMIQQLREIQGVSGVHVMA
HRQESAVADIIKKSGVLDERRPWVPDSEQQRGEQQRGEQHKLAAGFGHE
>A0A7X2FUM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HT1-32|TrEMBL
MNASTPDRDLKNPVTWPFELSFQGTPEPPTVSFEFFPPKTDALEASLLTAARRLESLGPE
FVSVTYGAGGSTRDRTHSIVRRLVDETSLKPAAHLTCVAATREEVDAVARDYWDAGVRHI
VALRGDAPTIGKAYEPHPGGYPFAVDLVSGLKRVADFDITVAAYPEVHPEARDADSDLDN
LKRKIDAGASRAITQFFFDPEVFLRFRDRAAAAGITIPITPGILPVTNFGRLKSFAGACG
TAIPDWVHDLFEGIDDDPETCRLVAASLAAQTCQLLMANGVFEFHFYTLNRAELSYAICH
MLGVRPKTRSDSGGQAA
>A0A7V7VFR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. CH99b_3|TrEMBL
MTQLLQALKHNILIADGAMGTILYSEGLDTCPEAYNLSHPEKVEHIHRSYIDAGADIIQT
NTYGANFEKLKAYGLEHKVKDIHQAAVKIAQQAANDDTYILGTVGGFRGVRQEDLSLSAI
QYHTGIQVDTLVEAGVDGLLFETYYDLEELTNIIQATRRKYDIPIVAQLTASNTNYLRDG
SEINSALQQLKASGADVVGLNCHHGPHHMQQSFSHIELPDDGYLSCYPNASLLDIDNSEF
KYSDNAEYFGSVAQKLINEGVRLIGGCCGTTPEHIKFIKSSIKDLKPVTHKDIIPITKHQ
TKTTTTSSKVNLTTKVKQRPTIIVELDTPKHLDTSLFFRNIKKLDDADIDAVTLADNSLA
TVRISNIAAASLIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVDEILTITGDPSKI
GNLPGAMNVFDVNSKGLTEIAQRFNQGINTDGDALKQATNFNIAGAFDPNVRKLDGAIRR
LEKKIDSGMNYFITQPVYSKEKIKAVYEATKHLNVPFFIGIMPITSYNNALFLHNEVPGI
KLSEEILTQFEAVKNDKEKTRELSISICKELIDTVHEYFNGLYLITPFQRVDFSLELAAY
SKTITSTKQEAIL
>A0A8B3FMD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium parmentieri|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWQSGIRHIVALRGD
LPPEGGKPEMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTSVFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPEVAC
>A0A6G8TXT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. 1(2017)|TrEMBL
MTDVTTPVTANGQDGHLRRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPAG
GIGTPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKNGVDTFHFYTMNRADLVFAISHLLGIRVK
SAQKAA
>A0A8H2VGU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kazachstania barnettii|TrEMBL
MSLIETYYQKDEPSISLEFFPPKTSSGKANLLERIGRMNVLEPTFVTVTWGAGGTTAAKT
IDLAGIVAQSFDIPVCMHMTCTNMDVSIIDNALEQCRELGIKNILALRGDPSVIANEDGT
PDDQFRYAVDLVKYIKNKYKDEFCVGVAAYPEGHYSTEDDSSIEQDPIRDMEYLKEKIDA
GAEFVITQLFYDADKFLNFEKVFRETISTTIPIFPGLMPINSYLLFNRAAKLSHASIPQH
IMDKFPPEIQADDNMVKSIGVNILMEIIDKIYKGTDGRVKCFHFYTLNLEKSIAEIVSES
PTLSHIIDESEESDADISSTDNMNEDDENDITNKHLDKNGDITLDNLSLNHDGRKRRRSS
VLSADLLFNRAIINKDSTSARNGFNEYSYKNGMPSKKFLLSISRGSGALGRDATWDEFPN
GRFGDSRSPAYGEIDGYGPTIKVSVKKAHEMWGRPTNIKDLKKIFIKYLEGSIEALPWSD
LGLSPETALIQEELIQLNHRGYLTLASQPAANAAKSTDKIFGWGPANGLVYQKGFVEMFL
HKQQWESILKPKLDHYGRRKVSYYVGDASGSFNTNLDEGSSNVVTWGVFPNSQVIQTTIV
EEESFKAWTDEAFSIWSEWAKLFPRNTPTNSFLTHVHSEYCIVSIVHHDFIETDELWEIL
LD
>A0A849UC33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium|TrEMBL
MQSQKKHPQLYSFEFYPPKTPEGAASLQIVQDKLAALNPEFFSVTFGAGGSTRDLTFDAV
IDIQSKGITAAPHLSCVASTKDNIRAILENYRAHGINNIVALRGDLPSGMMSAGEFRYAN
ELVGFIRQETDDHFQIHVAAYPEVHPQCANGVEDFKNFKRKVDAGANAAITQYFYNAEAY
FYFVDACEKSGIDIPIVPGIMPITQYSQLFRFSEMCGADIPRWMRKRLESYGDDRESIQA
FGLEVVSTLCQRLLEAGAPGLHFYTMNQAAPTLAILANLQR
>A0A847SYP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccus sp|TrEMBL
MKSGSNLERVLESGTFAVTAEIAPPKSTSTEGMRKKVRALMGCAEAFNLTDNQTAIVRLS
SMASSVACLQEGAEPVMQMTCRDRNRIAMQSDLLGAASLGIKNVLCLSGDHQTFGNQKEA
RNVYDIDPIQQLMVFRQMRDQGLVWGGDTIEERPKVYLGAAANPFADPFEYRVARLAKKV
KAGADFVQTQAIFDLERFERFMTDVRARRLDEQVHILAGVVPLKSANAARYMKTKVSGMS
VPDEVLERMKSASDPKKEGIKICVETIDHLRTIPGVHGVHIMAIGWEEMVPTIAEQSGLL
PRP
>A0A6F9WVJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp. SVR|TrEMBL
MRIIDTIVPNRPFFSLEFFPPKEKAEWPAFFQAVERLAGLGPLFASVTYGAGGSTRDDTL
EIVTRLQRDHGLETMAHLTCIGAYRGALLKFLDALAAAGVTNILALRGDPPKEVPPLFSA
CGTLRYASDLVAFISKAHPGLGLAVAGYPEPHPEAESAESDLSHLKLKLDNGGDFAITQL
FFDNRLYFDFVARARARGITKPIVPGILPVVSLKVIKRIVSLCGAYIPPAFLAELEEADA
RGGAAAVQQAGIAHARRQVRELLADGVPGVHLYTLNRAEAVLELTEGLL
>A0A822TCZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella sonnei|TrEMBL
MPVSNFKQAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKD
FHFYTLNRAEMSYAICHTLGVRPGL
>A0A1H7TWV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gallolyticus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADIIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAREAAGDDAFVLGTVGALRGLKQCDLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEAELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKETNFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDGLADLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALEHFKGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A5N8ZFK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MTNSSLAERIIRGSLLSDGAMGTELYAAGVNIGPIELANLEKPDLVKSIHRSYLQSGSEL
IQTNTFGANASRLAIHGISSQTEELNRLGVALARDAIRLTGQQAWVAGAMGPLAADSFAA
EILGSATAHNVFAEQASILTESGVDVLVLETFTSLAQLRLALAAVRSVSNLPVMATLTFN
NDGLTPAGDAPEEIATSLSEENLIAIGANCSIGPDLLRSVIERMSQNTNLPLLAQPNAGL
PSYVDGQLQYTAESSYFAEVMKDIVSSGATILGGCCGTTPRHIAAVRDGIKGITPQRKFA
KPAQILQKPSKHEEENKKPTGLAEKIIKGEFVVTVELSPPRGFDISDTVDKLREIAGHID
AVNVADSPRAQGRMSALATGSLIQSKLGIESIMHAAIRHRNLLALHSDLLGAHALGIRNV
FTVMGDVPQSGDYPQATAVSDVTASGLIRLMSGFNNGVDANGREIDSPTSFFIGAAFNFN
APDIDRELKVLDRKVAAGANFLLTQPIYSIEQFDRVYSILGEFPIPIILGVLPLRNTRHA
LFLHNEVPGILVPDQVVNRLNQSGEKSASVGIEISRELLQELSGKVAGAYFMPPFERFNV
VKETLDGLDL
>A0A8C5E3H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gouania willdenowi|TrEMBL
WLRQTSKKSGVTFCSSGGDSSKESSRCSTPVLDADRSDRLRDKMRKRIESGDHWFSLEFF
PPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESI
LHLTCCNQSKEKITAYLNKAKHLGLKNIMALRGDPVGSEWEDEEGGFNYAIDLVKHIRSE
FDDYFDICVAGYPTGHPEAETYEADILHLKEKVDAGADFVISQLFFRADTFLKFVNDCRA
IGIKCPIVPGVFPVQGYQSLRQLAKLSKLEVPEEITRVIEPIKDNDAAIRNFGIHQAVEM
CRLLLDSGIVPGLHFYTLNREVATMEVLRQLGLWNEDPRRPLPWAMSAHPKRKVEDVRPI
FWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEEL
MNEQSVYEIFTCYITAQSNPCGHKVLCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQ
PNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKILKKYEPRVNYHIVNVNG
RNWTNANDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPS
RMIVKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFDYFYRRCSLQTF
>A0A8H2VI57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kazachstania barnettii|TrEMBL
MKITEKLQKHHESSPKATFSFEYFVPKTTQGVQNLYDRMDRMYQSSLPQFIDVTWNAGGQ
TSKLSQSSTELVSTAQSVLGLETCLHLTCTNMPISDIDNALKEAYDSGCQNILALRGDPP
SNEYKWEPCKGGFQYAKDLVAYIREKYDNHFDIGVAAYPEGHPEEKDSIKNLDYLKQKID
AGANFIITQMFYDVDNFIQWCHTVRQFGIEVPIVPGIMPITTYSAFVRRCQWGSISIPSS
FIESLNPIKDDDELVRAKGTELVVEMCQKLLDSGYINHLHLYTMNLEKAPLMILELLDLL
PTETEFINDPVSVLPWRKSLNPQRRNEEVRPIFWQRRPYSYVARTSQWTIDEFPNGRFGD
SSSPAFGDLDLVGYSLFRQSPQKALQLWSTPKTMLDISQLVINYLQGKLVCLPWSDTPLN
HEVDTLLTHLIMMNKNGIITINSQPRINGERSNDKIHGWGPKDGYVYQKQYLEFLLPRER
LPKLKEALKDNDIMTYFAIDVQDKLSTNHPDGSKANAVTWGIFPGREVLQPTIVEKVSFL
AWKEEFYRILEDWKSIFIKDNDNESIQLLNSLITDYVLVNIVDNDFVSTEDQIFTLLMTL
>A0A353RB17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rikenellaceae bacterium|TrEMBL
MKLTEIFKVSEKTFSFEFYPPRDEIAAVDFGLNIGQLIKLSPSFVSVTYGAGGSTQSRTF
DLVDYLKNRVGLNTVAHYTCVGSTRSRTLEDLKTLRKLGLQNFMLLRGDPEVGSKYGFIP
CYDGFPNATELISFAREYIDDCCIGGGAYPEVHPESPSAEIDMKNLKKKVDAGCDFLITQ
FFFDNKRYFDFVARARKAGIKCRIIPGIIPLTKYAQLERFVNLSRASVPPAFLEQLESNR
YNPDAVYKAGMDFAIRQCRDLLMLGAPGLHFYTLNKSRTTVEIYQTLMVR
>A0LN01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)|TrEMBL
MSTTTPSKLQKILAAGHFGVTTECGPPRSCDGGVVEEKAKHVAGHVDAINVTDNQTAVVR
MCSLASCIRLRIMGLEPVLQMVTRDRNRIGLQSDLLGAASFGINNVLCLTGDHQSFGDHP
EAANVFDLDSTQLIQTVKLMRDDAKLLSGAELKTCPQMFIGAAENPFADPFDVRVSRLAK
KVAAGAQFIQTQCIYNLDKFKKWMQGIVDRGLHEKVHILAGFTPMKGVGMAKYMKNRVPG
MDVPDDIIKRLQGVPKEKQPDEGINICIEHIQELKEVKGVAGFHIMAIEWEEKVPEIVER
AGLYPRPKVD
>A0A3D3K1F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MKITEHIKNSNGKTLFSIEVIPPTKGTGIEDLYKNIDPLMEFNPPFIDVTTSREEYVYIE
KGNGLMERKITRMRPGTLGICASIQHKYDVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IVALRGDAMKGENHFVPTEGGHKYAVDLVKHINDLGRGKYLSGDINCADDNRFCIGVAGY
PEKHIEAPSMKYDLQKLKEKVDAGADYVVTQMFFDNKKYIEFVKQAREIGINVPIIPGIK
PIAT
>A0A5N9A5C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MAKVTDMAFEATGKTSFICDFSPPRSGDPQIVDQAQIDVDLISVAYNPGRAVRTNSAMLA
AAIKRSGKESVFTLATRDMNKLAVQSQLLGAQMLGVQNVIVVQGDPFNEKDRTMVSPVND
YRPTGLISAIAELNAGRDFRGGQLRSPTDFCIGATIDLRRGIEEEAQLAVRKVQAGAEFL
ITQPIFNVDVVARYRESYGYHAGKAGTFPIYFGLQILEKDGVLFSSVPDSVREELEGGRS
GVDIALDLYQKFQEARFNNIYLMPPIKRGGARNYEAAKEFLKKARNL
>A0A5N6DZ84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus parasiticus|TrEMBL
MHIKEKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAAEGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLEAL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIKDLSRLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLIE
LNHRGILTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDSWYLVNIVNNDFHNTYDLFELFKDLNVRDFDVEVAADNADLK
SQENETAETAAN
>A0A5N9GS81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MLIRDLLNQGTPSFSFEFFPPKTDEAFDTLVETIRELQKLHPTFVSVTYGAGGSTRRRTV
DVVAKAKRELGQESMAHLTCVGSTEDELRDVLDELKAQGIENVLPLRGDPPAGTDVFEKT
PGGFGYANELVSFIKKNYDFCLGVAGYPEGHQEADDFDTDLANLKLKVDAGADFVVTQMF
FDNHFYFDFVEQARAIGIDVPLIPGIMPILNVEQIKRFTRMCGASIPEELLERLEAIKED
ADAVRQCGVEHAAKQCRELLEGGAPGIHFYTLNRSTSTRDIFENLKAVGALA
>A0A5N9ELA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MVAFHLYGQRTSPTEKLHRRNKSAGGDWIPGLKIKDILTKTRPISFEFFPPRNAEGIPAV
LETMDELKPYCPDFVSVTYGAGGSTRAFTEEITLQIKRETGVEVMAHLTCVGQNKEEIHE
VLQRLESEGVENIIALRGDPPRGSTEFAPVEGGFQHATDLLKHVQSNFRFGVAAACYPEG
HTESVDLDTDLDYIKMKVDNGADFLVTQLFYDNRHYFDFLERAHAGGIDVPIIPGVLPVL
NSAQVRRFTALSGSEIPPDLDKLLDKYADSENSARDMGVEYATAQVRELWDAGVPGVHFY
VLNRSYSVSRILDNLTISGHQRQD
>A0A259CU95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilaceae bacterium 17-44-8|TrEMBL
MTQPITYSFEFFPPKTVEGIANLREARLALAKYKPEFFSVTFGAGGSTRARLALAKYKPE
FFSVTFGAGGSTRDRTMDTVFEIQAEGYAAAPHISCISSSKEEIRELLNAYQAKGIKRLV
TLRGDVPSGEVSAGDFKYANELVTFIRQETGDWFHIEVAAYPEFHPESPSAAKDIINFKR
KVDAGANSAITQYFYNADAYYRFIETCEHEGIHVPIVPGVMPIYNYTQLARFSGVCGAEI
PRWLRLRLEAYGDDLASLRAYGADVVTEMCSRLIDSGVKSMHFYTLNQAGTISKIIQNLH
Q
>A0A1Q9B0J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium oryzae|TrEMBL
MTTPERMPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQEVYARAAIFEGWVDGINAVD
ASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGAAAMGVSNILCLTGDG
VQAGDQPGAKPVFDLDCMSLLETIRIMRDQAKFLSGRKLTCPPEVFLGAAINPFAPPYDF
RPYRLAKKIAAGAQFVQSQYCFDVPMLKRYMETVRALGLHEHCFILIGVGPMASARSARW
MRANVPGVHIPDSIIARLEGAEDQKAEGKRICIDIINEVKEIEGVAGIHVMAYRQEEYVA
EIVHESGVLNGRRPWRREPAPDEAALRERLGNLDEEVIEQPTDMAAEAAGDAPAT
>A0A3L9Y937|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ulvibacter antarcticus|TrEMBL
MKVLEHIEKANGKTQFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYIYEE
QQNGLLKKKIVRKRPGTVGICAAIQNKYNVDAIPHILCGGFNKEDTENFLIDLGFLGIDN
VMALRGDAVKNETYFTPEKEGHLYANGLVQQIAAMNNGTYLEEGLLNTTPTSFCIGVAGY
PEKHFEAPNMDSDIHFLKKKIEDGATYIVTQLFFDNKKYFNFVDKCRAAGITVPIIPGLK
PLSTKKQLNLIPQRFNAELPEELIKEVLKCTDNRGIRQVGVEWCVMQSKELKKANIPFLH
YYSMGKSDNIKEIAKNLF
>A0A357BE24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MKITDHIKNANGKTPFSFEIVPPQKGVGIADLYQNIDPLMEFKPPFIDVTTSREEYIFIE
RGNGLMERKITRMRPGTLGICAAIQHKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEPTKGGHKYASDLVKQIRDLGKGEYLHSKIKCGEENSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKYFDFVKQAREIGIDVPIIPGIK
PIATKKHLQLLPQVFKIDLPETLINAVLKCKTNTDVREVGIEWAIQQCKELLDFGVPVLH
FYSMGKSDNILKIGREVF
>A0A249NUY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. CCBAU 05631|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMEIQLFQTISDLSVFAPAFQTVTYGAGGSTKAR
SLTTVKRMIGEMGLNNTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGSA
YEPFPGGYESSASLVKALRARGDFEISVSAYPEKHPESADVAADIDMLKRKVDSGATRAI
TQFFFDNDDFERYLERVRRAGVQIPVVPGILPINNLTQVIRFAGLCGSKVPEAIISRLAH
LDDQPEERFKEASHIAAEQIVDLARRGLRDFHLYTMNRSPLIAAVCELVGYRRRPVRPAA
APSYPAVATA
>A0A7W0XZT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriaceae bacterium|TrEMBL
MSSAAGVSAPVPTTQHVGDRRANQTVRAPTIAELLRDGRRPLFSFELFPAKDEAMQRQLW
QTVRELEALGPDFVSVTYGANGSSRDRTIAATEAIARHTTLRSMAHLTCASQSKNQLRQV
IGSYAAAGIRHILAIRGDMPGGPTVPWERHPEGLANATELVAMVAELGDFCIGVAAFPDL
HPERHNADLDARVLVAKANAGANFAITQLFFTPSRYFELVERVRALGCDIPIIPGIMPVT
RFSQIKRFAELSGADLPTAVTDRLNEVADDEEQVRAVGVELATELSADLLAGGAPGLHFI
TMNRSRATREIFARLHPGLRRA
>A0A1E7H2Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium C00003096|TrEMBL
MGNAKPVFDLDSVQVLDMISHMNRGFVLDSKAPFGGIKLAPMSFHAGCVVSPFKRLESEL
IPQYLKLKRKVAAGASFVITQMGFDVRKFDELRRFMDREGLKVPLLGTVFIPTTGLARTL
CKGEIPGCILPDRLLERIEQEAISDDQEGGPRLERAARLVSILKGIGYEGVHLSGPGLKY
SHVEWVIERANDISERWKLFTCQFLFPEEWKFWYFKEDPETWLNHDEPNPGSEVSLSLRD
SLGLSLGRLFHELAFEPGKPLFNSLRRMAGWIDGSSSKRHFTSFEYWLKEWLYDCRRCGD
CALGEMGFLCPQSQCSKFLLNGPCGGSRDGWCEVWPGRQQCFYVKVYERLQSLGKQESLG
GPRIPPRDWTLDSTSSWLNFYLGRDHHRIG
>Q0CXY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus terreus (strain NIH 2624 / FGSC A1156)|TrEMBL
MHISEKLAQNEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALQSAYKAGCTNILALRGDPPREKEK
WEATDGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSSF
IVTQMFYDTDNFINWVKKCRAKGINVPIIPGIMPIQTYAAFMRRANWTKIRIPPEWLEAL
EPVKNDDAAVKEIGKGLIADMCRRLLAAGINHLHFYTMNLAQSTQLVLEELNLTPSEETP
LQKPLPWRPSLGLNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSIRDLAHIFVKFMQGELARLPWSDTPISGEANAIKDKLIE
LNKRGLFTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLVPPYLLDELIARIEKNE
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHEAGSPSRKLIQDVMDNWYLVNIVNNDFHNSFNLFELFDGLDVKDIDTEIAPEPKPQE
NGTLNEATNGAALEASVRN
>A0A2E4RZD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium|TrEMBL
MSHLSVATRQGEKGPNVSFEFFPPKNETMDERLWECVRRLEPMAPHFVSVTYGAGGSTRE
RTHDTVKRIVTDTRLTPAAHLTCVGAPREEVLQTAEDYYEAGVRHIVALRGDAPQDEDYD
KPEGRYTNVVDLVSDLRAHRPDLGKVFEISVACYPEPHPDSRGWEQDLAHLKRKQEAGAD
RAITQFFFEPEVYFEFVDKARAAGITMPLVPGIMLQPNFNGLKKFAKMCGASLPDWLHKL
YEGLDDDADTRDLITANVAAELCHKLADGGVEQFHFYTLNRANLALSTCHLLGLKPATAE
AA
>A0A3D4TPW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVEVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
AKLCQRLVEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A1Y5G0M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium 50_400_T64|TrEMBL
MTKDWLLSFEFFPPKTQPGAEKLARTRETLATLAPEYFSVTYGAGGSTRDNTRDIVLETR
AAGLDVMPHLSFAFGDDDANAIQALLETYRKAGVSRLLALRGDLPSDPENTRKPIHANEL
VAFIREHFGEQFTLQVAAYPEIHPDAKSYKDDIYWLGEKFKAGADGAITQYFFNIDAYWH
FLEQAAKAGIDKPIVPGIMPITNFTNLARFSASCGAEIPRWMAKKLEQYGDDQASIIAFG
ADVVTQLCERLLEGGAPGLHFYTMNQAEPSVDILSRLGVSPEQN
>A0A427PVH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. FDAARGOS_515|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKIVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTAVAPHLSCIGDDKARIAELLDLYQSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAETFDADIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERLEKEGITIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1Y3Y2Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Collinsella] massiliensis|TrEMBL
MRIDDIFAQAKEAGRTPVSFEMFPPKGELTLDRAREAAGALSALSPDFISVTCSAGGGGN
FGQTAAIAHMIEDEFGVSSVAHLTCMSLTREQLAARVEEYRAAGVHNVLALRGDRPTPES
PAFGAPSDYAYAAQIIPTLVEAGFCVGGAAYPEGHIECEDLATSVRHLKLKQDAGASFFV
TQLFFDNEVCYRFLDLAEKAGITIPITCGIMPFMSRAQISRMVFMCGASLPSPVIKLLAK
YEDDPESLVKAGIDYACRQLVDLRDHGVDGLHVYTMNRPSVARAAMGALS
>A0A090EA47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium plurifarium|TrEMBL
MTDTRVIEANGNAAGVDLHLGPLPGFSSLGRLERILRRGDFAVTAELNPPDSANAQDVYE
RAAVFDGWVDGINAVDASGANCHMSSVGICALLTQIGYAPIMQIACRDRNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDHPGAKPVFDLDCMSLLETVRTMRDESRLMSGRKLSKPPA
VFLGTAINPFAPPFDFRPHRLIKKIAAGAQFVQTQYCYDVPMLREYMKRVRDLGLVEKCY
ILCGVGPLASARAAKWMRTNVPGVHIPEAVIARMEGAADQKKEGKQICIDIINEVKEIEG
VSGIHVMAYRQEELVAEIVQQSGVLKGRQPWRHKAGANDREPRDAQHDPAHSLRVVGR
>A0A0T5ZRR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium CSP1-2|TrEMBL
MRFPEYFKDGGKPIISFEIFPPKTDKGMGPLLEIIPELVALGPDYITVTYGAMGSTQHRT
LEIASLIKNVYKMETACHLTCVGASRNELDEILRRISDSSIRNIVALRGDPPQGDKTFIP
PSDGYAHANQLVEHIRRLESEKGQEPFGIAVAGYPEKHIEAPSMEIDIANLKRKVEAGGD
IIITQLFFDNEFFFNFVERARTAGITVPIIPGLMPILSVKQIKRITSMCGSSIPHELQLE
LESAADDDEKASEIGIRQCIRQAKDLLSHGVSGIHFYVLNKSTHIRKIIEALRV
>A0A1B2EJA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga ossetica|TrEMBL
MSPLTLRPSRQVSCPIKVSFEFFPPKTPEMETTLWASIQRLAPLNPQFVSVTYGAGGSTR
ERTHATVSRLVQETQLKPAAHLTCVAATNEEVGDVVRSYWDAGVRHIVALRGDPAGGIGT
AYEPHPGGYRQTCDLVAGIKAIGDFEVSVSAYPEKHPEAASLEADIDVLQAKVDCGADRA
ITQFFFDNDHYFRYLDRVRARGIDIPVVPGIVPVQNFKQTANFASKTGASGPDWLAARFE
GLENDVETRKLVAAAVAAEQVIDLVDRGVNEFHFYTMNRADLVYAICHLLGLRDQSVKAA
A
>A0A453M855|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aegilops tauschii subsp. strangulata|TrEMBL
AANGRTVFSFEYFPPKTEEGVENLFERMDRMVAHGPNFCDITWGAGGSTADVTLDIANRM
QNMVCVETMMHLTCTNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDKFVQVAGGFSC
ALDLVEHIKAKYGDYFGITVAGYPEAHPEVILGEEGATEEAYSKDLAYLKRKVDAGADVI
VTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTKIPAEITAALD
PIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNLGLIEESKLSR
TLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWGDSRNPSYGALNDHQF
TRPRGRGKKLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPETTIIDDQLVK
INSKGFLTINSQPAVNAEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFP
SLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRG
WACLFPEGDSSRELLEQIQKSYYLVSLVDNDYISGDLFAAFKEI
>A0A3R6KVR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM54-37XD|TrEMBL
MKIRDIIGQEKATLSFEVFPPKKDTDFASVEAAALGIAALRPSYMSVTYGAGGSTKGHTI
KLANEIQEKYGVPTIAHLTCVCANKDSIRTALSEMKNAGIENILALRGDIPKNYDGQVFT
DFAHASELVKLIKESGDFCVGGACYPEVHPDSANKQDDIANLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRIREAGIAVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEVAAGIQANLSDILLV
>A0A2D8ZRT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium|TrEMBL
MSSLATPRQAGSPSVSFEFFPPKSEAMADRLWETVERLEPMTPNFVSVTYGAGGSTRERT
HDTVRRIAQQTHLRPAGHLTCVSATKDEVLSVAEDYWEAGVRHIVALRGDPPSGMGEKFE
QHPGGFRDSIDLIEGIRAHRPDLGRCFEISVSCYPELHPESQGWDAEIAFLKAKQDAGAD
RAITQFFFEPEIYLNFLEKARAGGVTMPIVPGIMLQPNFKGLKRISQLCGASLPTWLHEL
YEGLEDDQETRELVTANVAADLCRKLSDEGVSDFHFYTLNRAGLALSTCRLLGLKPKPVE
AA
>A0A850M954|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Helarchaeota archaeon|TrEMBL
MSERAFSDLMREIKAGKFVFTGELEPEKTTNLHELIEGAKVMKDSVVAANVTDNPQSMAY
MSSLVAAGTVQKESGLEMVYQLRCSDRNRIALFSDLLGAGHLGIKNILALTGDHTALGDM
PGAKPVFDLDSGQLCYLIRKMVDDGTDLNGKEIHDPPKFHVGVAGNPNCEPMEAEVLKLG
RKIEAGAEFVQTQVIYDVELAKKFLKEMERYNFPVLIGIFPMKSYGVADYFDKYIPGVSV
PKDLLTELKAVKKSGLEKPAKKQKYADVNFNFFVPFIKEIMKTTKAAGVHVMAVGWEPIV
VELIKRARGE
>A0A6P1Q4C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mixta intestinalis|TrEMBL
MSFFHANQREALNQSLAELNGRINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRAIAQDYWHNGIRHIVALRGD
LPPGGGRPEMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPGWMNSMFE
GLDDDAETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPATALVA
>A0A5C3EL56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ustilago trichophora|TrEMBL
MASTSTAAVPSVPDPAHITTKIQAASARDAPFWSFEFFPPKTTQGLANLYNRIARMRANL
DPSWIHVTWGAGGTTGGKSLELAGRIQKGKLNPDVQLVQSEVHQIGSGSQQHIERVKGGE
SWEGEGELDACDVCLHLTCTNVEKSSLDETLFTAKRLGIKNILALRGDPPRGEEYWVAAD
ERFQHATDLVRYIRESHGDYFCIGVAGYPEGHADYVDRDVKRDLRYLKEKQDAGAQYIVT
QLFYDVDQFLSWYKDCRDIGITIPILPGIMPIQNYQSFRRMTNLCKAQVPQLVLDALEPI
KSDDAAVKEYGVSLSIHMIGRIFLESDVRGFHLCSLNLEKSIERILDGLGWKVDLGAQAE
AEARLKGIPAHLHLERTKNQMLSDRTGANTPKDFKVTTQEALNRTLARTSSSYQVPETST
WDEFPNGRYGDSRSPAFGEMDGYGVSLKVPPQDALRIWGYPVTLSDISTIFASYLEEKIS
CIPWCDAPLMNETLQIRDHLLTLNRPGKSWWSVGSQPAVDGAPSTDPTVGFGPPGGFIFQ
KAFVELFMSSQDKDALISRIDALGPNSQVTYFAGNAKGEFASNLGENEANTVTWAVFPGK
EIVQSTIIERESFEAWREEAFEIWSEWSMLFPKGSASRKLVEGVKEERWLVTVVHHDYKD
GEGLWRFLAE
>A0A3S4X6L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trueperella bialowiezensis|TrEMBL
MPTDLASPEAFGWLPAPESTQLPAHITTSFEVMPPRNPAAAPKFWTTVKKLVDARPNFIS
VTYGAAGQDRRGAREVTEIFARHIPTPPIAHLTCVGTSINEITQIVTDYLDSGVRTFLAL
RGDPPVNKPDWSPADDALQRATDLIQLIREVDYKRATASSSFALQSALAPIRIAVATFLN
GNPASGTTREQEISRLLQKQLAGADFAITQLFWCARDYADFVAEARAAGVTIPIVPGILP
PVETRRVLRTQELTGVTPSPRILEALGNTNTPEEAEAVGVDIAADLALEVLAEGAPGIHL
YTFNRAEPALAVMAKVARQHRA
>B3PGF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrio japonicus (strain Ueda107)|TrEMBL
MIDSQPRLSFEFFPPKTAEGKEKLLRVRDQLAQFAPDFFSVTYGAGGSTRDNTKGLVTQC
KADGISVAPHLSFGGDDEATIKALLQDYQTTGVDRIVALRGDMPSGVGGAYQLVYANELV
AFIRQHFGDHFHLEVAAYPEIHPQAKSYSDDIRYLKGKFDAGANSAITQYFFNPDAYFYF
IEQCIKIGITQPIYPGIMPIINYKNLTRFSDTCGAEIPRWLRKALENYGDDEESLRAFGV
DLVTELCEVLLENEAPGLHFYTMNQTEPTAQIVRNLGLIPTE
>A0A6B3A9Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8014|TrEMBL
MALGTASTRTDHAPTVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSEDWDTDIRYFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LQDDKG
>A0A2G2EN09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp|TrEMBL
MSKQPVISCEFFPPKTEKGAQNLLLVQERLAVLKPEFYSVTFGAGGSTQDNTLEAVIAIQ
QRAAETGIGAAPHLSCVGSSKERIRTILQTYIDNGISRVVALRGDLPSGMRDPGDFRYAN
ELVQFIRKETGDHFTIEVAAYPEVHPQAQDAGVDLENFKRKVDAGADSAITQYFFNIDSY
LYFVERCQKKGIDIPIIPGIMPINNYTQLARFSAACGAEIPRWLKKRLEEFYDDSVSMQA
FTTDYLTEFTEKLIKLDVPGLHFYSMNKTQPVLTVCERLGLVR
>A0A519KIS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MSTPISLAEARALLLSPLGPVARAGQDASRPRVSFEFFPPKSDEAEANLWKAIQRLAPLN
PAFVSVTYGAGGSTRERTHRTVERLLAETALQPAAHLTCVDASREEVDAVIAGYKAAGVT
HIVALRGDPPGGAGIGGVYQPRADGYANATELTAAISRVGGFDITVGAYPEKHPESPSID
HDIDVLKAKVDAGATRAVSQFFFDMDAFLRFRDRVRAAGVTIPLIPGIMPVSNFAGLQRM
CGACGTAIP
>A0A841V215|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa BLCC-F158|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDYI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDMAGIPPIHN
>A0A7Y7RG61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. B6002|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLHNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A843RGX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiloniellaceae bacterium|TrEMBL
MVDTRRNTENLRPTTQGHNLLPRFSFEYFPPATPAAEERFRDTVVRLGDLAPDFVSVTYG
AGGTTQERTFKAIDWVRRETDLQPAAHLTCVGASRAQIDAVAEKYWESGVRRIVAIRGDA
PKGSSGYEPHPQGYAYAADLVAGLRRVADFDISVSAYPEVHPEARDAAADLDNLKRKFDA
GAKRAITQFFFDPDDYLRFIDRARAAGIEAPIVPGILLIVNFDRTRQMAESCKAAMPRWL
IDLYAELEEDNEVRFPVAVSVAAELCRYLMARGAEDFHIYTLNRADLTAALCRLLRNDRR
SREFPIEKPMLLAGGLS
>A0A807N813|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus sp. T2.5-30|TrEMBL
MPSTDPKPGTVAELFRSAHGPLFSFEFFPPRSEEEEPVLWAAVEALAPLQPAFVSVTYGA
NGSRRDRTIRATRRIAESGGPLTVGHLTCVAQSKAELAEALAEYLEAGVTNILAIRGDMP
GGGPWERHPEGLANATELVRFIKSEGDFCVGVAAFANPHETSNDPDLDARILLDKVEAGA
EFAITQLFFEAERYAELVERMRGLGCEIPIVPGIMPLTVITQIERFAALSGRALPDALVS
RLRACASKEEVREAGLAAAVQMSRDLLAAGAPGLQFFTQNRSKATREVLAEVLTTAR
>A0A8F9Z3L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Minnesota|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7G2JWZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae HK1212|TrEMBL
METLLWDSIHRLKVLKPKFVSVTYGANSGERDRTHGIVKAIKQETGLEAAPHLTGIDATP
EELKQIARDYWDSGIRRIVALRGDEPKGYAKKPFYASDLVELLRSVADFDISVAAYPEVH
PEAKSAQAD
>I7H648|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter cinaedi CCUG 18818 = ATCC BAA-847|TrEMBL
MFGIEFLPQEIYEDIECLKAMIQGARENLGQEVDFVLIPSNPVNKASISSLLGAYALRER
FSMIVDSGFSSVVEFVPTISGAGQDKLQIFSQILSVKYGGFSSVALIGGDNGELDGVKLI
ALAREILGGEVSLVSGSGVKIWKKEIEQRLTQKLQAGVDRIITQPIFSIESAKKCVEHFY
VLQERLGIQAQLSLGVFGIFSAESAYRINKSHLGFDIPRSYLRALEQGGVKEGFESLWQD
MQGLAREYNVSLYLSTPKHNDLRAYGNGLC
>A0A3R7IHE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicycliphilus denitrificans|TrEMBL
MSLPVSFEFFPPKTPEGADKLRAVRRQLYARAPQFCSVTYGAGGSTQEGTFATVRAIIEE
GVDAASHFSCIGATKAGVRQQLAELKAMGVKRLVALRGDLPSGYGLGGEFQYASDLVAFI
RQETGRDFHIEVAAYPEMHPQARSPEADLQAFATKVRAGADSAITQYFFNADAYSRFVDD
ARRLGVEIPIVPGIMPITGSSQLMRFSDACGAEIPRWIRLRLQGFGDDTASIRAFGQDVV
GRLCEQLVRAGAPGLHFYTMNQSAATLALCERIGC
>A0A238Y991|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura mexicana|TrEMBL
MRRVRPDRPPTVRELLASGERSFSFEFFPPKTDKGARNLWRTIRELESLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAVGVRNVLALRGDPP
GDPMGEWVKHPDGVEYAAELVRMIRSYGDFSVGVAAFPYKHPRSRDIESDTRHFVAKCRA
GADYAITQMFFRAEDYFRLRDRVDAAGCDVPILPGIMPVTRLSTIERSEQLSGAPFPPEV
RARFEAVADDPEAVRRLGIEHAAELCCELLEQGAPGIHFITFNQSTATREVYSLLDGAGY
GARGSVPPITA
>A0A3P6TQV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litomosoides sigmodontis|TrEMBL
MDPVTSDNGSRMNVVSNHDVLYVGSQKTTDQATISSDSIIPQACGKKRSELSTNWISGGT
YVPLRDRIKKRIAAGVPFFSLEFFPPKTENSVANFFARLDRFREGNPMFIDIAWHFGSDP
GNINSETSSSSVAAGCVDCGMDTMLHVTCCPYTKEQSIKHLEQSKALGLRNIFALRGDLP
RQLLKYATSCERKIAYVVSRLEGENPTVCKYRALDLIRWIKEKYNDYFTIVCSGHPAGHP
EAPSYRADLLYLKAKVDAGADFIISQIIFDGKIFKNFLRDCREIGIAVPIIPGILPIQSY
ESIRRVAELSQLMIPDSVLVSLESIKNNDDAVRNFGVWLAVELCRTLFTSGSTTSVHLFT
LNQEVSSRRILQQLGLWPLSPVRALPWRTFGDIYAIRCKEDMRSIVCSVRPESYVFRTCV
TIDWMNTESAVPVAVTWSVFPGSEIGQRTVVDPPLFRIWLLALGRNDLCDFLMRVDIIQ
>A0A7R6XSL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 131-2-1|TrEMBL
MEKIIGIQNVRPASIDASIEMAPSQALDSPDLPGLLPPDVRVYITDIGLADTPTLVKAAR
RVTDLGYAAVPHIAARRQTTREALETRLKAFAEEAGVRDVLIVGGDVAAPAGSFSSSIEV
LETGFIDKHGITEVGIAGHPEGSRDFGEEAAIAALRMKSAWAERSGARMRIVTQFGFDAD
KFITWADGLAACGLDLPVHLGVAGPAKIMTLLKYAALCGVGNSLNFLKKRSASLAALATS
HSPESFVGPIEDHLRAKPGSAIAQLHVFPFGGIKNTARWLYERGSWQSCDADDRSSIA
>A0A6I5YVY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. CAP-1|TrEMBL
MPVIHPNWERPPVNMVDGYSLEMTAKDVESLKSTATAIAPETPIAVTFLPGEEPAARIEA
TRLVRGLGFEPMPHFSARRIRSTDEFETYLAAAVAEAGVKRCFVVAGDPSEPEGPYFDSS
ALIASGAFERAGISAIGIGGHPEGHPNMSKDQCWAVLEEKCTQIDQRGMAPLIVTQFVFD
ADAVLDWLAELRARGIEAPVRIGVPGPAGIKTLMRFAARCGVGASASVLAKYGISIGKLL
GSAGPDRLVERFERGFGPEHGRVRLHFYPFGGLEKTVAWINNYARAH
>A0A3R6T7D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM54-14XD|TrEMBL
MKLKEYIQTKRIIADGAFGTYYISLYGDGSRAESGAGLSNLPELANIKAPERVIGIHTEY
IEAGTQFVRTNTFASNTKSLSADMEKVKENIRAAVMCAKMAAGKVDREIYLAGDIGPIPV
EGMLHSDRLTQEYIAIGETLLSQGIDILLFETFPELETILPAVTYLKENHDCTILVHFSV
NQFGYSNTGLSAKRLIAEANACPYIDGTGLNCGVGPGHMEKLVRKIAPDDTTFLSVFPNS
GYPKYLNNRLTFTDNAEYFTEKMEEIAALDVGIFGGCCGTTPEYIRRIAAGISADHPVRK
TETEEEKITVSEHPAYGFMERRVKEPAHKLIAVELVPPLNANDEKLLDAAHILKNAEVDV
VTFPDSPSGRTRADSVLMAEKIRLETGLCVMPHICCRDKNAIAIRSTILGSSLNHITNFL
LLTGDPVPVLFRQTTKSVFNFDSVGMMKIVQEMNSDTFTDHPVTYGGAINHNRMNTKAET
ERIRRKMAAGATFFMTQPIFSAEQADVIRQMKKETGATILVGLMPLVSRKNAVFMKNEMT
GIEIPDTIIERYREDMSREEGEACGVQIAREFMAVTDDFADGYYFSFPFNRVHMLKKILK
>A0A174D6W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MDDIRAFLSRKPLLFDGGMGTYYKAAPGTDCEQANLTDPAGVRKVHAEYLAAGADAIKTN
TFSLPRLAAGHVPGWEKLADAGWKLAAEAAAETGAAVFADLGPAPDTEAVPAAQVYTAVA
ERFAALGAKNFLFETLSSDVGILEAVRAVKAQVPEAFVLVSFAVLPDGYTREGVYCKDLV
RRMTESGCVDAVGLNCVSAPGAMRTLARGLAGGALPLSVMPNAGYPVVTRTQVRYQGKPE
YFARELSGLAAEGAVRILGGCCGTTPAHIAALRAALDALPERKLPAEPAKRSTTEVKPVE
NEDAFLRKLNAGEKVIAIELDSPRNADLTGYLEGARKLQAAGADLLTIADCPIARARMDS
SLVACRVHRELGMCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEV
KNVYQFNSRKLAQYIVSLAGEDREMPTPMTVFGALNLNARNFDVELRRAGEKLENGMSGF
LTQPVLSEQAVENLRRTRETLGSRAKILAGIMPVVSQRNAIFMENEINGIHVDEEIIQKF
AGLDRAGGEELGLAISLEMARKALPYADGFYLMTPFNRVALMERLIAQLRTEVLQES
>A0A1Q7VDD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_20CM_4_57_11|TrEMBL
MKIHDFNERLKDSILIADGAMGSMLHEAVGTQRCFDELNSTEPEAVFRVHQAYIEAGAQI
IETNTFGANRFKLAPLGLGEEVQRLNSRGGKIAREARESAAREVLIAGSIGPLGLGVQSR
HPADDEILDIFHEQALALEERGVDLYVLETFSYIEELLLAIDAIRSFSGLPIVAQLTYAE
EGTIYGDLRPSDAASQLKNKNVQVIGANCTLGPQALLPILQELAAVDGLRVSGMPNAGFP
KREGDRIVYPKSSPEYFALFAREAAGLGVRILGGCCGTTPAHIRAMAEAVKSFRPAKTHA
VAHSVATVAKPAPISEREPESKFWRKLQAKKFALCVEIDPPKGLSLDRIFEQVDKVMASK
KVDAIDINSGAMARVGMDALIVAGALEARGVGTVPHLTTRDQNIIGLQAALLGAWTVGGV
RNVLAITGDPPSVGDYPETSGVYEVDSVGLVKVLHRLNQGTDWAGKTLGGATNFTIGVAL
NPVADDLDNEIERFHAKVEAG
>A0A8C3UAA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catharus ustulatus|TrEMBL
RALTMVNETQQTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQD
AGDKWFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIAN
TAVNYCGLETILHMTCCNQTKDDITRHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNY
AVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPE
TFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAI
RNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAH
PKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPR
EELLKMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKEQLEKV
NRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYEL
RVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQ
WAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLNSPTQ
>A0A0M2U4X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium PH28_bin88|TrEMBL
MNLKTESKLEKLFAQGEFVVSGEIGPPKNANGAVVRHHAEEMKDYVDGMNLTDNQTAIVR
LSSIASAVHVLAAGGDPIIQMTCRDRNRIGMQSDLLGAYSLGVRNVLALSGDHQSFGNHP
TAKNVHDIDSIQLVKALKDMRDDKNFICGEEMKEHEPRFFIGAVANPFGDPFEWRVARLE
KKVNAGADFIQTQCILDMERFEKWMEMVRQRGLHQRVKIMAGIMPLKSWRAAKYMQESVS
GMLVPNEIIDRMKNASDPKAEGVAIAVEQIKHLRNMEGIAGVHIMAVAWEEIIPTIVKEA
GLYPRPKVS
>A0A0C9MNY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas paucimobilis NBRC 13935|TrEMBL
MTNTILTQAEAALAHEEPLFADVGGDIAVSFEFFPPKTEKMDAQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTLAAAAHLTCVEATREEIDQVAQEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPDSADQQADIDNLK
RKIDAGATRAITQFFFSPEAYFRFRDAAAAAGIAAEIVPGILPVSNVAQTRKFAGMCGAS
IPDWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKGFHFYTLNRAELAYAISHML
GVRGKKAETVAAA
>A0A1F8N934|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_57_8|TrEMBL
MSLQSKLESGRFAISCEFGPLKGTDTHEIKENIEILRGKVDAVNVTDQQSSVMRLCSLVT
STLCVQGGLDPIFQMTCRDRNRIALQSDLLGAWVMGIKNVLALTGDLPSLGDHPQAKGVF
DLDSVTLLMAIKRLNEGFDLAGGELKGKTEFFAGAVVKVDSNTEASGELQIAKFAKKIAA
GAKFFQTQAVYDAGTFGKFMKRIEKHKVPVMAGIIPLKNAGMAKYMNANVAGVHVPDDVI
QRMSAAAKEDREKVGIQIAADLIKKMKPMCQGVHIMAIGWEKKVPEIMAAAGL
>A0A316DUY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomarina spongicola|TrEMBL
MKVTEHIKNANGNTQFSFEILPPLKGQNVQSIFDNIDPLMEFKPPFIDVTYHREEYVYKE
LENGLLQKKVVKKRPGTVGICAAIQNKYRVDAIPHILCGGFTKEDTENFLIDLDFLGINN
VMALRGDAVKTETYFKAEKEGHNYASELVTQISELNKGNYLDEELLNSSATDFCVGVAAY
PEKHMEAPSLDSDIHFLKKKIKYGAEYIVTQMFFDNQKYFDFVDKCRKEGIKVPIIPGLK
PIATKKQLNLIPHRFHVDLPEELILEVVKCKDNEQVRQLGIEWCIKQSKELQKAGIPVLH
YYSMGKSDNIKAIASQVF
>A0A2J5HHW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus taichungensis|TrEMBL
MHIKDKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMGVEKVDAALQAAYKTGCTNILALRGDPPREKEH
WEAVDGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNSDVDQLIDHLKEKVDAGSSF
IVTQMFYDTDNFINWVKKCREKGIHVPIIPGIMPIQTYAAFLRRANWTKIHIPPSWLEAL
EPVKNDDAAVREIGKVLIADMCRKLMASGINHLHFYTMNLAQSTQQVLGELKLLPSEETP
LQRPLPWRPSLGLNRRGEDVRPIFWRNRNSSYVARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLSHLFTRYLEGKLDRLPWCDTPITSEASEIGGELLE
LNKRGLLTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLVPPYLLDELIARIEKNE
DLTYHAVSKSGELRTNTRDTPNALTWGIFAGREIVQPTVVETVSFLAWKDEAYRLGEDWS
KCHDAASPSRKLIQGIVDSWYLVNIGRFLIVKASDKLVTDYVRSEQRLPQHIQPLRAVQG
SGRKGSRRRSRRGREAPASCGC
>A0A1Q8DU75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. Cmf 22.2|TrEMBL
MSKPAFSFEFFPAKTELGHEKLLGTYDELNKLSPSYFSVTYGAGGSTRSRTLNIVQALCA
RGETDIAPHMSCIGDDKAEIAELLTHYKSLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFEFDVDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTAVQPLVAGIMPITNSSNLMRFADSCGADIPRYVRKQLADFGDDRTAIREF
GFEVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVEALGLVS
>A0A124I9W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces caeruleatus|TrEMBL
MALGTASIRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGDWVRHPQGLTYAAELVELIKASGDFCVGVAAFPAMHPRSADWETDVGHFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAAGCDTPIIPEIMPIASLRTLERIPSLTNASF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A2C9P5W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Macclesfield str. S-1643|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRAIAQDYWNNGISHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A098S9I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeodactylibacter xiamenensis|TrEMBL
MKVTEYFEKANGQTLISFEVLPPLKGGSMQAIFDTLDPLMEFKPPFIDVTYHREEFIYKM
RSSGYYEKTAIRKRPGTVGICAAIMHRYGVDAVPHLICGGFTKEDTENALIDLNFLNINN
VLALRGDARKFDGKFVAEEHGHAYAIDLVKQIAEMNEGKYLDSNIEKGAKSDFCIGIAGY
PEKHFEAPNMDADMEFTKAKIDAGADYIVTQMFFDNQKYFDYVDKCRANGINVPIVPGLK
PMTKKYQLNALPRIFHIDLPDDLVRGIRDAKDAEARRQVGIEWCIQQSKELKAAGAPCLH
YYTMGDSKTIQQIAEAVY
>A0A1H8WZQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis saalfeldensis|TrEMBL
MTSVIERLQGDAPAFSIEFFPPRDEADEAVLWKAVRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLCPMAHLTAVNHSVSELRNVIGWYAAVGVRNILAVRGDPPGDVYGDWV
PHPQGLKYAEELVELVRSLGDFCVGVSAFPYGHPRSPDLETDTKYLVRKFRAGADFAIAQ
LFFEAEDFLRLRDRVAAAGCDAPVLPGIMPLTTLRTLRTTIRLAGVPAPQRLLDRLEPLA
DDPKAFRAAGIDVVTDLCEKLIAEGVPDLHFYTFNRSKATREVVGRLGLVPARA
>A0A640TSN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces libani subsp. libani|TrEMBL
MALGTASTRTDRAHTVRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVRHPDGVGYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVA
KCRAGADFAITQMFFYPEDYFRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A1Q5AQ79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MJM1172|TrEMBL
MSGLRELLASGQRSFSFEFFPPKTDAGERVLWNAIRRIEAMAPSFVSVTYGAGGSSRDRT
VEVTKRMVAETTLLPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGNPNATWT
AHPQGLRHADELVSLVRASGDFSVGVAAFPEMHPRSPDWDTDIRHFVAKCRAGADYAITQ
MFFHVEDYLRLRDRVAAAGCDTPIIPEIMPATDARQIGRFAELSGAAFPEELAGRLEAAK
DNPADGHRIGVEYATAMADRLLAEGAPGLHYITLNRSTATLEIHQNIIESRSAHALAHG
>A0A6I2JKW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. RIT698|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKLVHQELQLLNPEFFSITYGAGGSTRERTLAAIADFN
GKGTPVAPHLSCIGDDKVRIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADNFDADIQHFAEKVKAGANAAITQFFFNPDAYFYFV
ERIQKQGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVIKLCERLIAGGAPSLHFYSMNHTEPNRQLVLDLGLA
>A0A358U7I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp|TrEMBL
MAEEKSKLQSLFEQGEFAVTCEIGPPKNAQGDGIRKHTEHLKPFVDAVNLTDNQTAIVRL
SSIGAGVHVLAAGGEPIIQMTTRDRNRIALQSDLLGAYSLGVRNVLCLSGDHQTFGNHQG
AKNVYDLDSIQLIQTVKDMREAKVFQSGEVIKQGEPRFFIGAVANPFADPFEFRVLRLEK
KIRAGAQFIQTQCIFDMERFEAFMDLARKRGLHQQAYIMAGVMPIKSAKVAKYMQKNVSG
MLVPDGIVERMSKAVDQPAEGVKLCIEQIKHLRTIPGVRGVHIMAVAWEEIVPEIVKGAG
LLPRP
>A0A806G6J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aggregatibacter actinomycetemcomitans ANH9381|TrEMBL
MSYAKEIDNLNQHLADLNGKINVSFEFFPPKSEKMENLLWESIHRLKVLKPKFVSVTYGA
NSGERERTHGVVKRIKQETGLEAAPHLTGIDATSDELRRIAKGYWDSGIRRIVALRGDEP
KGYEKKPFYAADLVALLRDVSDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPAWMSKMYEGL
DDDQTTRNLVAASIAMDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGIRPSL
>A0A015X7M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis str. 3998T(B)3|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A1G4MJJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea fermentati|TrEMBL
MSYIRERYEALKGPFISLEFFPPKTLPGKRNLLARMARMTALNPLFITVTWGAGGTTAEK
TLELASLAQRELSIPVCMHLTCTNTDKEIIDHALEKARLADIRNILALRGDPPVGEEWDS
NNGSGEFKHAVDLVQYIKQNYPDDFSVGVAAYPEGHCEGEADGLLQDPRRDLPYLKEKVD
AGADFVITQLFYDVEKFLAFEEMFRCEVSEDVPLFPGIMPINSFLLFNRASKLSHASIPK
RILDRFPPEIQADDSKVREIGVDILVEIIDEIYERTNGRIKGVHFYTLNLEKAIAQIVSK
SAVLSSILEEDQSDEEDAEGDIVLEDIDTTKEDENLRKRRRQSSHNSDVISNRVLVDQDG
NFTANRSASGAPSRKVVVSISQGSGTLGKDATWDEFPNGRFGDSRSPAFGEIDGYGPSLK
VSAKKAYHIWGKPENLRDLTSIFIRYLEGSLEALPWSDLGLSPETALIQEELIQLNERGF
LSLASQPATNSTPSTDKIFGWGPPGGYIYQKAFVELFVHKSRWESELKAKIEPHGSKFSY
YLGDSAGDFQTNLDPHGSSVVTWGVFPNSEVLQTTIIEEDSFKAWRDEAFSIWLEWSKLF
PRNSAANTFLRQLHRDFYLVSIVHHDFTDCDGLWNTLLS
>A0A0J1H1C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium ganghwense|TrEMBL
MGYSYAGHLDALNQNIADLNGNINVSFEFFPPSSEQMEQTLWQSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLIAAPHLTCIDASRDELRTIARDYWNNGIRHIVALRGD
LPEKGIKPDMYAVDLVELLRAEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNMKQAKRFASTNNVKIPGWLEKQYE
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAETA
>A0A0J6Y9H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccidioides immitis RMSCC 2394|TrEMBL
MEKISNKIAALPEDANYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT
ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPPRSDE
YNLDGEDDSNKEFTYAVDLVRYIRKKHSDYFCIGVAAYPEGHSDESHPGVQDPVRDLPYL
VEKTKAGADFIMTQLTYDLEAYKRFESMLRNHESGVFKTIPIIPGLMPIQSYPRLTRITK
LSHVRVPPEMLSRIEACKKDDEAVKKVGVDILSELVEGIKTIPGTGPRGLHFYTLNLEKS
VSFILERCNLIPPSSEASSDTDSDSVFASGNLQNGLGTAAGKPPLISRRRASSLNSQPHN
RVIVDRADISSQSSITHEASAQGAGMPALNPPHRNTALQISEGMGALGREATWDDFPNGR
WGDARSPAFGEIDGYGPSLHVTANVARRLWGYPTTREDINNIFRQHVSGGLHAVPWSEGG
AAEETGGLSPETITIRPYLLSLIEKRGWWTIASQPAVSGVRSDHPIFGWGPPGEGFVFQK
AFVEFFCSKDDYRSHLKPLLQRYGHDEFAWFATNAAGDFESSTSSSIPVPTGPVDAVFDD
MDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWDEWRRIFPRGSPT
EKLLNRVKEDTWLVCVIGQRFGAGGDPGKDAMEEGKILWKVLAGENVSLQS
>A0A2S4ZKJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ru62|TrEMBL
MDPALLDDFSLEMTGKDVPGLEEARDSVPPGTRINITFLAGEDTATRLTAARAVRRLGFV
PVPHISARRLPSRTALEEFLAGLAADGTAENVFVVGGDPARPEGPYEDALAVLRTGLLRR
HGVRHIGVAGYPEGHPGIADRVLWSALTDKAAAIGAGRFTGDVITQFGFDAAPVLAWLEA
LRARGVHLPVRVGVPGPAGVRRLLRYAGRFGVGTSASVARKYGFSLTNLVDTAGPDRFLH
ALADRYDPARHGTVKVHFYTFGGLRTTADWITRFRHGSERISEERQTARS
>A0A2N6ASF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKKEQNMKIRELYTKDEPVISFEIFPPKKDKPIDVVYDTIESLKDLRPGFISVTYGAGGS
TARTTIELASAIRNKYKVETLAHLTCAASSKDEITGILDTLGENGVQNILALRGDLPAEK
GFKFPDSRNFKHAGDLVSHIKSHGGFCVGGAVYPEGHIECENLALDLRHVKEKVDAGTDF
LISQLFFDNELYYDFLDKAAQTGIDVPISAGILPVISKNQMEHIVKLCGCNLPPKFTRIL
EKYANKPEALREAGIAYAIEQIIDLLSWG
>W8HH51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus opacus PD630|TrEMBL
MTRTPSIVDRIRSSSDGRVPFSVEFSPPRDEAAEARLWRAVREFERLGPAFVSMTYGAGG
STRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRGISNILVLRGDPPGD
PLGEWEKHPDGVEYAEDLVRLVRDLGDFHVGVASFPEGHYRAPDLAHDTRFLVSKLRAGA
EYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSVRRVLELSGSRLPAH
LEKRLATAAGDGPEENRAAVREIGIDVATEMSERLIAEGAPGLHFITLNFARATSEVLAR
LGDKVGSGVADPAPVTPARVS
>A0A3D5B3V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKISDVLQKGKGTLSFEIFPPKGDFDVQGVRSLLGALSPLSPAYISVTYSAGGSKNNRLT
EEIASMAQEENHIPSACHITVINSTNEEVENTIDSFHRRGIENVLALRGDKVDGAEGGSY
LHATDIIPSLVKKGFCVGASCYPEGHPLSPSLAEDYRYMKLKQDLGASFFVSQLCFDNRR
FFEFFKGAEKAGVTAPISAGIMPIMSKAQVNRMIFMC
>A0A061EKK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Theobroma cacao|TrEMBL
MKVIEKIRTLQEEQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGSDGVATPEAYQNDLEYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPADITNALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRFLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSQN
PSYGALTDYQFMRPRARGKKLHEEWATPLKSIDDIQEKFKSYCLGKLKSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSTSVGKYNLPEFAVVLRIGGNTQSLM
>A0A523K0L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNESTHDSAQFTPIKSRLSVSFEFFPPKTAAMEETLWASIKRLAPIGPRFVSVTYGAGGS
TRERTHATVKRVLDETPLTPAAHLTCVGATRDQVDAVARRYHDAGIRHIVALRGDPPNTQ
ARFTAHPDGYQNAAELVSGLKRVADFEITVGAHPEVHPDARSAEADLDNLKAKLDAGASR
AITQFFFDTDVYFRFLDQARGAGISAPIIPGILPVTNFAAVQRFAATCGASVPDWMAELF
QGLDDSPDTRQLVAATVAAEQCLRLARQGVTEFHFYTLNRAELTVAICHRLGLKGGATAG
GTQSFASGT
>A0A7U9BAL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli TA271|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8J7G080|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elainella sp. C42_A2020_010|TrEMBL
MSNSSPAELAFPISRFQQAVEAKEFLITAEVMPPKGGDPTHMLQMAQLLKGRVHAMNITD
GSRAVLRMSSLAAAVLLRQHGLEPVCQMACRDRNVIGLQADLMGAQALGIQNILALTGDP
IKAGDHPTARGVFELESVRLLKLIDKLNRGVDFNDKPLPDGATALFAGAAVDPQCPSWSG
LQRRFERKVEAGAKFFQSQLISDFDRLEKFMDQIAASCNKPILAGIFLLKSAKNAQFINR
NVPGVQIPQDLIDRLERATDPLDEGVQIAAEQVKLARQLCQGVHIMAVRREDLIPQILDR
AGVAAVAG
>A0A6L8EM55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MLFEDEPIAGENLPILPGHVSPGRLERVLRAGGFAVTTEIAPPDSADPVEVYERAAMFDG
YVDAINATDGSGANCHMSSVGICSLLTRRGYAMVMQVSCRDRNRIAIQGDVLGASAMGVT
NILCLTGDGVQSGDHPQAKPVFDLDSMSTLEMLRGMRDDGRFMSGRVITSPPRVFLGAAA
NPFAEPFDFRPSRLARKIMAGAQFIQTQYCFDMDVFSRYMARVRDLGLHEKVYILAGVGP
LASARSAAWIRANIAGIHIPDSVIRRLRGATDQAREGVNICMDMIHQVREIEGIHGVHIM
AYRQEHRVAEIVESTGILQGRTPWHPGIARRQEETRLREVG
>A0A2E0EXP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSDNIKTLEQTLNSDGFAITAEIPAPISASAIEMEEKIDLLKGHVHAVNVTDNPGATAHM
SSLAGCNIVRXKGIDPIFQVTCRDRNRLAIQSDLMGASALGINNVLTLAGDPIKNGDQAD
AKAVXDINSXKILSIMQSMNDDGQTMSGRELQTRSKFFPAGAAIIHEPEENWEPVALKEK
AELGAKFIQTQFCYDVDLLKTYMKYIVDSGLSEQLFFIVGIGPLRSDKSAKWMRDKLFGT
VIPDSMVQRMEQSENQIEEGIEICAELINQFQEIDGVHGAHLMAPRNLSAIAPTVKKAGI
KI
>A0A8H7DHV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycena sanguinolenta|TrEMBL
MKVIDKIKDHGPSNPFYTFEFFPPRTDQGFDNLVARIERLSDLNPLAVSITWGAGGSTKE
RSLDLAAVTQAEYGLDTILHLTCTNMEQGMVDDALKAAKERGIQSILALRGDPPRGEEEW
TPTDLRFTHGADLVSYIRSLPEYSSQFCIGVAAYPDGHTGQLHDERAEISFLKAKIDAGA
DFIVTQLFYDVDGFLQWVRKVREAGITVPIIPGIMPIQTYSSFLRLTKLCGTRVPDSVMD
ALEPIRNDDQLVKDYGVQLAVEMIKRLTTEGGIPGVHLCTLNLEKSVQRVLENLKWTGSS
EIAKNKLIEEAPTQNDLTITASSATSSAKLGLATLPTIEGEAGRGELNNAASWDDFPNGR
FGDFKSPAFGSTGLWGGPAIGHADIIAQCGHPRTLDDLTAIFLAYLHSKIPITPFSPAPL
SPESLMILPHLERLTRRGWWTVGSQPAIDGASSGDEVVGWGPRAGYVFQKGFVEFFCTKA
DVDATERRVRERGNGWVHWFAGNKNGECRGNVPEGGRNAVTWGVFPGQEIAQTTIIERAS
FLSWKEEAFSIWSEWASLYKPQSKERILLENVCDERWLVSIVHHDYRNTQALWTFLFDDS
PIAA
>A0A127PY89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas pratensis|TrEMBL
MRLIALEQIVQRGHLAGWPLLPAFADRVGLHSDLSPLEGAGALGDPASSLLHFSGKDRGR
ADLLLQMESMKARGLEQLLLLSGDRLPGHHPDQAPVRYLESVPALQIAREHCPDWLLGAA
LNPFKYREEEGGAQYLKGQKKLLAGADFFTLQLGFDTAKHIEAQTWMRAQVRMKPMLACV
MRLSDKRAAVLQTVPGIVITESTRELLGREQQVSQAYASARSLERLALQIVGLQLMGYAG
VHVCGVHTLDELLSLEQAIAEQRESMSSLTDWIERWHASWQMLGAPEVCFVPAIGAWEMG
QSNVAATPRERLRYALLSTVHGQFFSRTGWLSRTLGWSMRRPFWKVGVAADALHAVERTV
KRPLVGCDTCGSCRLQETLYVCPETCPKGLANGPCGGTQLNRCEFADRECVHSVKYRIAK
SANQLPVLAQTLIPCIEAGNRHRSSWPEWFEPKDSTPGR
>A0A6L7TH81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGGTNFHLSFEFFPPNTPDGWSKLLRSARRLQNENPDFFSVTYGAGGSTKHRTFQTVKDL
RAEGLNVNPHLSWGDVSREEISLTVQSFLELGIEGMVVLRGDSPSGSVPSVMHNASELVR
LVRHEIASDLQIYVAAYPEMHPDAQTPSKDLEFLLEKVQAGANACITQYFYNADAYLNFV
ERCRGFGINVPIIPGVMPIYNYDQLVRFSQNCGAEIPRWIERRMHEYRTNKKALEEFGVD
VVTELCERLRVQGAPGFHFYTLNRALIPRQILQNLNLQRATV
>A0A7S6MPX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MESQKKFSPTFSFELFPPQTPEGVEKLRLTRQQLARFNPKFFSVTFGAGGSTRERTLETV
LEIQTEGHVVAPHLSCIGSTQENIRAILEKYHQAGIRHIVALRGDLPSGMAQAGEFRYAS
ELVAFIRQEYGTSFHIEVAAYPEYHPQARSAQSDFENFKRKIETGASSAITQYFYNADAY
FHFVELCEAAGLNIPVVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLESFGDDSQSIQA
FGLDIVTDLCERLLQAGAPGLHFYTLNSANLTSIIWQRLNLQSNSN
>A0A7C7WIL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MLNRYHQAFAERDFIFSAELPLKPNMSAPDVIADAQLLYENVDGIILTDNQYGSTHMSTT
AAASLLLGSAIDPILQLSCRNRNRTALISELLGARALGVSSVMLIEGAKVPKGFEPRPKS
VLDMSTKDLIATAALINRDENLSGPKLNIISSGTVHSPQPGWQPEELTAKADAGATSVIS
QLCFDVDLLKRYMSNLVAKRMTHRMQFIISLATLPSARIAEFMRDNRRRALIPPEVIKRL
EQSADAESEGVAICSELLQQYEEIPGVRGVNITTLGSVDTIGAAIQASGIRREQE
>A0A7C3D6W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNTTNKAYSCEFFPPKTEKGANNLRTTLADLAELKPAYFSVTFGAGGSTQAGTFDTVKQI
QENGYNAAPHLSCIGGSRDSIRELLNQYIEIGVNRIVALRGDMPSGMQEMGDFRYANELV
EFIRTETGDHFHIEVAAYPEIHPQATSAEKDLQNFARKAKAGANAAITQYFYNPDAYYRF
VDDCNKLGVEIPIIPGIMPITNYSNLKRFSDMCGAEIPRWIAKRLEGFADDKASIVAFGE
EVVTELCNNLLDNGAPGLHFYTMNQAGPTRTLWQNLGLENN
>A0A1X3RYD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lonsdalea britannica|TrEMBL
MSFFHANHQEALNQSLAELQGHINVSFEFFPPRTSEMEGTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKAIKERIGVDAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPPEGGKPELYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRVPNWMTAMFD
GLDHDPETRKMVGASIAMDMVKILRREGVKDFHFYTLNRAELSYAICHTLGVRPAIAA
>A0A1C3ND36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora krabiensis|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVAHPEGVRYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCQAGAAFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQMGTIERSVQLSGAPF
PPALAERFAKVADDPEAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLS
VDVRA
>A0A3R6RRP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. TM07-1AC|TrEMBL
MKVIDLINGSKTTAFSFEILPPLKGNSIQKVYNVIDRLKEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQNTDLYHEHATDLQQQVNDFNKGIAIDGSTFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYFSFVDRCRAEGITVPIVPGIKPV
VFKSQLTVLPKIFRSDIPEPFAAELRKCKNDDEVKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMATDSVYKVAKEIY
>A0A370WTL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella monticola|TrEMBL
MPAISFEFFPPKTDEQRTQLDKTAKELKALKPEYVSVTFGAGGSTLSYTSETVARLHQQH
GLDVAPHLSCMGGTRKEIAELLDTYRAAGYKRIVALRGDLPSGMATPGDFRYAAELVRFI
RQHSGDHFHVEVAAYPEMHPQAEDVQADLRHFKAKIDAGANGAITQYFFNADAYFCFVDD
VRRMGVTVPIVPGIMPISNYAQLKRFSDACGAEIPRWIAKRMQAYYDDADSIRAMGAEVV
AQLCRRLLEGGAPALHFYTLNRAKATRAVLEQLH
>A0A2E3DBD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MFQSNGFLFTTETTPAVTTDLAESAGRIDSLVGIADAVNVTDSPNCKSSLSSLLVSSEIR
KKGLDVILQLTGRDINRIALESELLGALSIDVNKVLCLSGDQPPEDGPRPVNELNSAGLI
ELCHQIGQGFLADRVEIKNPLPLFPGAADDLYEQLSKPDSIEKLLLKKKQGAMFVQTQFC
FDFEVIQKYSEILDAHRSLDDCKILIGMGPLKSAKQADWMRKNLWGINIADEILSRLELS
DKPEETGENICRELIEKVMDLPRVDGVHLMGPSCEERSARIISSFR
>A0A5D2JLY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium tomentosum|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DALMKNCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGAFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSTLYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A5D2JLW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium tomentosum|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQVYKMFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELD
GLQPETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCS
LDKLDALMKNCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGAFPAKEIIQPTVVDPAS
FVVWKDEAFEIWSRSWSTLYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A2E2HA91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSFTDKNEKVSVSFEFFPPADLSKADNFWDSVENLAKLQPDFISLTYGAGGSTRERSLEI
LKRLVADTSLTPVAHLTCVAVSKDEANEMARQFHEIGIRRLVVLRGDPPEGDNLSTVHPD
GYANATEFMHGLNKIADFDMSVAAYPEIHPESPNMEHEIEVLKQKVDAGARRFITQFFFD
CDVYLRFVEKARAAGIDIPIIPGILPIVNFNRVRGFAESCGASIPPWLEKLFEGVEPSST
INNMLAASVLIDQCNTLYDAGVRNFHFYTLNKSELTRAVCKTLGIQEKDTK
>A0A523MKR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MATDIQVSFEFFPPATEKMEATLWRSIQRLAPLQPRFVSVTYGADGSTRDRTHRIVRRIQ
TETDLTCAPHLTCIGATREEVLATASGYWDEGIRHIVALRGDTPKGVTKYVPLTNGFAYA
TDLVDGLGSIGAFELSVAAYPEVHPEADSAESDLDNLKRKIDVGATRAITQFFFDTSAYL
HFRDRCAAAGIDVVIVPGILPITNFPRMLKFAASCGTNVPQTLHQRFGGLDDDPETRRMI
AASVAIEQVDELRRQGVDEFHFYTLNRAELTYAICHTLGLRPRADEQELAS
>A0A127QB83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas pratensis|TrEMBL
MAQKNFSIEFFPPKTPEGTEKLRVTRAKLAELHPRYFSVTFGAGGSTQKGTLDTVLDIRS
EGHEAAPHLSCLGSSRESLRAILAQYKDHGIKRLVALRGDLPSGYGAMDFSSGEFRYANE
LVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDVQRYVSKVKAGANGAITQYFYNADAYF
RFVDEAQKLGATVPVVAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTDSIRAF
GLDVVTQLCERLLVGGAPGLHFYTLNHSPATIAIWQRLKL
>A0A2D8ALA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDSTNASFSIEFYPPRTAEGESTLDAVHAELAALGPEYFSVTYGAGGSTRAGTSKLVLKY
RAAG
>A0A2E4KVZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MLPTKISAVPHLSIGVSSDATLDQLVEYYQDIGVARILCLRCDQPSGDASKPAYAQGLVE
RLQQRFPRQFELAVAAHPEVYTDASSAIDDLAHFVAKVNA
>A0A2E8L382|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDSANASLSIEFYPPRTAEGESKLDVVHAELAALGPEYFSVTYGAGGSTRAGTRKLVLKY
QTAGSEVAPHLSFAGTDELDVRDLLQSYRGAGIKRLVALRGDIPSGGGAPTHYRYANELV
EFIREETGDYFHIEVACYPETHPEARNFSRDVAYFKQKVDAGANAAITQYFYNVDAYFRF
VDYCQSQGIDIPIVPGVMPITNFDNLKRFSSKCGAEIPLWLGNRLEDFGNDTDGMRQFGI
DVVTELCFDLLEGGAPGIHFYSMNLAKSVSQIWNNLSLQLQQRDA
>A0A534BC65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MQTLADRLRSREFVVTTELTPPKGLDLSELFAKAQALKDCVDGFNLTESPRARMTIEPKA
VAHLLLDRGLEPIVQVTARDRNRIALQADLLGAAALGIRNFVFMAGDPPSSGDHPDAKPV
FDLNTNEMLRAAAGLARGRDLAGNELRGAPQLFLGATANPGAEDLSAEAVNTRRKIEAGA
QFLQTQALYDAGTLERFLEAVKPDGVAVLAGIIPLKSAKMAAWLNTNVPGIRVPDALMRA
MQGVADTEAETQTGIDIAAQTIRDVRQLCAGVHIMALGLESEIPAILAAAGVRGAGMRGA
RTP
>A0A2E8J0Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSNFYQACVSKELVLTAELPLKPDASASTVITDAKSLLTHVDSILLTDNQYGQVHMSTMA
AAGFLIDAGLDPIVQLSCRNRNRIALLGDLLGLRAMGVNSLMLIQGTKVPKNFQPRPAAV
IDMKPRELIATAKLINEDEGLGRHEFLIVASGTIHDRKAVPQQEELLAKANAGARLIITQ
ICFDIELLKRYIGDLVRRKLTHRLQIFVSLATPPSAAKAAFLRDNRRRALVPDAIIRRLE
QSVDAEAEGVAIASELIQQYAEIPGVTGINLVPVDSLETAKSAIELSGVLGN
>A0A534CDI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPILPGHTSPGRFERVLRAGTFAVTSELAPPDSADPEDVYRRARIFDG
HVDAINATDGSGANCHMSSLAVCALLTRMGYAPVMQISCRDRNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQALPVFDLDSLSLLEAARTLRDEHHFLSGRKISYAPRVLLGAAE
NPFAKPVEWRAQRLAKKVAAGAQFIQTQFCYDVPLLRAFMRQVEELGLLDKVFILVGVGP
LRSAKAAEWIRTHVPGVHIPDEIIRRLAGASDGALEGRKLCIELIQEIRTIKGVHGVHVM
AYRQEETVAEIIERSGVLSGRVPWYPGRDPQANTNRMAS
>A0A349TME6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDSENSPFSIEFYPPRNAEGESRLDAVHAELAKLNPDYFSVTYGAGGSTKTGTSKLVMKY
QAAGSQVAPHLSFGGTDEQEVLELLQTYKEAGIKRIVALRGDIPSGSGAPMHYRYANELV
KFIRKETGDYYHIEVACYPETHPEAKNFSDDVAFFKQKVDAGANSAITQYFYNVDAYFRF
VDYCDSQGINVPIVPGVMPITNFDNLKRFSAKCGAEIPLWLGKRLEDFGDDVTGLKQFGQ
DVVTELCYDLLQGGAPGLHFYSMNLSKSVSQIWSELGLQDRNT
>A0A1E8S278|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC065B04|TrEMBL
MATVHPALSFELFPPRSQASCESLLRTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSSAE
LHRIGVEYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEY
A
>A0A2E9KQ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKISYEFYPPKDLDYRKVVDEFSLIRDFGPRFISITYGALGGSQKKSIGLIKAFKENTDI
DIAAHLTLVGKSKDELSLIVDDFKSLGVNKIVAIRGDSPEGKFKSHPNGFVNTSDFVEFL
VNENMEVFVSANPEVHPDSESFEFDLNLLRQKTLAGSNQAISQFCFEMKAYKKLINAISK
NNIQNELIAGIMPIYNIQNLCNMAERCGTKIPKEIVRKFSNNPADNEKAAIEICIKQLED
LQTMGVNSFHFYTLNQSTLLRKIFDEIGVLS
>A0A534CKI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPILPGHTSPGRFERVLRSGAFAVTTELAPPDSADPEDVYKRARIFDG
YVDAINATDGSGANCHMSSIAVCALLTRVGYAPIMQISCRDRNRIAIQGDIVFDLDAVSL
LALGKTLRDEHHFQSGRKITFAPRVFFGAAENPFAEPLAWRHQRLAKKVEAGAQFIQTQY
CFDLERLELFVRGVEELGLLDKVFILPGVGPLPSAKTAEWMRRNVPGVHVPDTVIRRLAG
AERPKQEGVAI
>A0A1I2KGU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salegentibacter agarivorans|TrEMBL
MKVTEHINRAKGETLFSFEIVPPQKGRSIQDLYNNIDPLMEFNPPFIDVTTSREEHVYIK
KDDGLLERKITRMRPGTVGICAAIKQKYNVDTIPHVLCGGFTREETEYLLVDCHYLGIEN
VMALRGDAMKHQRYFEPTHGGNCFASELVTQIKDLGEGKYLNEVIESNNNADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKINAGADYVVTQMFFNNKAYFDFVEQAREAGITVPIIPGIK
PIAVKRHLQLLPQVFSIDIPEDLIKNVEACKDNKEVREVGIEWAIAQSKELKASGVPVLH
YYSMGKSTNIQKIAKAVF
>A0A1Q9YGP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium NYU-BL-F16|TrEMBL
MGTLFAQNTSKPSTKTEAANRMDPDTIVQIHKDYIQAGCKAIKTNTYSLADELAQNLSGQ
KEEYISDLIQAAVFNARQAIKESDCHEEIYVFADLGPISAEAKSDSLLIYQKLISIFLEQ
GVRNFLMETLPDTEWIDEIADWLKNTCSDSFLLVSIACAADGITRSGKSGIEQIKILDQM
ESVDAVGFNCMCGPSHLLNLVKDLPELHKPLSVMPNAGYPSILSRRTVYDGTPDYFASGM
ISLIHHGAVILGGCCGTTPEHISALFKELEQEKKKILEDVDHLNKCSAQETEKKVHSDED
PELGIPNPNSFKDGKEPGILLKNHAAKRKSYLVELDPPANDSISFFLEGVSRLKHSGADM
VTIADNPIGRPRADSSILACKIKREAGIEVLPHMTCRDRNLNAIKALLLGLSIEDVHHVL
LVTGDPLPSDLRQEVRAVYSFNSRMLAGFVKTLGESKTCTPFHMYGALDINARNFDVQIR
IAKEKEANGMEGFLTQPAFSDRAISNLKRARKELKGLIMGGLMPIVSYKNALFLANEISG
MDIPESIIEKYKVLSREEAEQLALSIVLKTADQMGDDVDGYYIMTPFKRVSLSQKIVEQI
RKMEEEKLN
>A0A7S6RDE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabaenopsis elenkinii CCIBt3563|TrEMBL
MQDTQNPTVFNSFRRAAQSGEFLVTAEVAPPKGVNVAHMISMAATLKGRVHAVNITDGSR
AVLRMSSLVASVILLQNGIEPICQVACRDRNRIGLQADLMGAHALGIRNILALTGDPVKV
GDHPHAKGVFDLESVRLLQLIRKMNQGVDCHDKPFPDGGTDLFAGAAVDPQSPSWSGLQK
RFERKVEAGAQFFQSQMITDFDVLEKFMDIIALSHNKPILAGIFLLKSAKNAEFINKCVP
GVNIPQHIIDRLATAKNPLEEGMKIAAEQVQMARQLCQGVHMMAVKREDLIPQILDLAGI
TPVSYVN
>A0A8E1UG37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae DGI18|TrEMBL
MNYAKEMNALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRSVVDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A257ADV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon ex4484_138|TrEMBL
MDFKRKIETGKFVVTTEVAPPRGTDTTLLIEEADLLSGCVDALNVSDNQRSIMRMSPLGV
AHVLQEQGHEVILHTTCRDRNRLALQSDLLGAWNLGVRNILAMTGDHPLLGDTMGTKPVY
DLDSTQLLQAIQNLNRGHDIMNRRLDGGTGFMAGAVVRPDPNDKMQLLRLKRKVSCGARF
IQTQPVYNTEEFKEFIEKVSHLNTHIIAGILPIFSLKTVKFINDKLPGIIIPQEVVERIK
NSTDPAEEGIELAAETIKKLQDVAGGVHIMPIITHQHTEAILKRAGMLH
>A0A7W5TAA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK619|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGVSIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGINEFHLYTMNRAPLVSAVLDNLGFSRRAAKSAGAAA
>A0A501VRJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus xiaochunlingii|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYTVDQIVDLVTQDVAGIHLYTMNNAEVAHQVYKATEALFHHKTKFEVS
>A0A1Z9U5X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium TMED284|TrEMBL
MKVTQYFENAGDSTLFSFEVLPPLKGQHIQTLFDHIDPLMEFNPPFIDVTYHREEFEYKK
LPNGLMERKTVRKRPGTVGICAALQNKYKIDAVPHIICGGFTKEETENALIDLNFLGIDN
IMVLQGDARKPDRDFXPEXGGHAYASELLEQVVELNRGIFLDDELEQAHHSDFCIGVSGY
PEKHMAAPNLELDMKYLKQKVDKGADYIVTQMFFDTQKYIDFVTKCREMDINIPIVPGLK
PITSLRQLTILPQIFHIDLPYDLSNALEKAKNNDQAKEIGIEWAIQQSKELIEFGVPTLH
YYSMGKSESVYKVAREVF
>A0A5C1YBA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces intestinalis|TrEMBL
MTAQGPDSHTAGRPPVSFELFPPRSDAAALALGRTIDRLAEARPAFISVTFGAGGSTRDR
SLTVLRYLLEHTDVEPMAHLTCVGSTHEEANRLVREFLDAGITSFLALRGDPPVGVDPHD
PDAGLGELRTAAELVQLIHRVQQEREPFGTATMSGVPGASRIADRPRPERVAVAAFPTGH
PRSRNLSQDIDALLAKEVAGANLAITQLFWHAEHYLDFVERARAAGVTIPILPGIMPVTS
PARLARLTELTGVVPPSELEIGLEVEPDLEAQTELGVAFAARLVSDVLAGSPPGVHLYTF
NRHEAVLDVLERVGITDERTASER
>A0A2U1V6K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas aestuarii|TrEMBL
MNHFADHAAPEAPQGAQLGSSQTGAPGTLQRWLTGPRVAGLPVPTELPPPALSFEFFPPR
TEALEQQLWTCVRRLEPLAPRFVSVTYGAGGTTQERTHATVARLVRETSLTPAAHLTCVG
ASRGEVDDVARRYWADGVRHIVALRGDAPAGEAGYVPHPDGYAYAADLVAGLRKVGDFEI
SVAAYPETHPTASSAQHDLDNLKRKIDAGATRAITQYFFDTEVFLRFLDRCLAAGITVPI
VPGILPVSNFNQVRKFSAMCGASVPGWMGKLFEGLDDDPDTRRMVAAALAAEQVRLLQAN
GVDEFHFYTLNRADLTYAIAHILGARPKVAAAL
>A0A3S1K7B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M5C.F.Cr.IN.023.01.1.1|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETVLTPAAHMTCVDAARHEVDEVIQEFAEMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFD
GLQKDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A4S2J6F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S816|TrEMBL
MLAGGKTTYSFEFSAPKTPKGERNLWTALRRVEAVAPDFVSVTYGAGGSTRAGTVKETQQ
IVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGAWVAHPKGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVVEAGCDTPVIPEILPVTSVRMLERLPKLSNAQFPDALKERILAAKDDPAAV
RSIGIDFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLGLHHPPQA
>A0A516V4Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter lycopersici|TrEMBL
MAARVPISFEFYPPKTDEQREQLDRTVEKLKAHAPQFMSVTFGAGGSTLSHTPETVQRLR
SEHRVAGVPHITCVGGNREEIRALLKLYRALGCDRVVALRGDTPSGMVRSGDLRYASELV
ELIRAEHGRHFHIEVAAYPETHPQAGDALVDLRNFKAKVDAGADGAITQYFYNTDAYFRF
VDDARALGIEVPIVPGIMPISNFSQLRRFSEACGAEIPRWIGQRMRAYGDDADAIREFAS
DFIARMCERLVAGGAPGLHFYTLNLARPTLAVLRRLGTDPA
>A0A0M2HCM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium trichothecenolyticum|TrEMBL
MSIDLSTPPVPISFEVYPPRSDAGVAALHETIRHLASVDPRFISVTYGAGGSTGGRSLEL
LTHILRETHVDPLAHLTCVGNTYAGANALIREFLDAGITSFLALRGDPPAGVSEDDVFLG
DLDSAAQLVQLIDRVQAEREPYSETPIPGVPGAVRLAERPRVDIAVAAFPNGHPRSRHPF
EDIDALLAKQAAGATLAITQLFFHADDYLAFVQRSREAGVTIPILPGIMPITSPTRLRRV
LELTGEQLPADLAVALDIEPTVEGQREVGVAHAARLAREVVDGGAPGVHLYAFNNHETVL
DVLSEAGVLDPATRMPDAVR
>D7J691|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. D22|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>R6T9W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea formicigenerans CAG:28|TrEMBL
MTCKIRDILKDQTPQVSFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKN
TVSIASHIKDDFGVTSLAHLTCVSSTREEVHRVIDKLKEKNIDNILALRGDIPKDNAFPL
PNQYRYACELIEDIKQQGDFCIGAACYPEGHVETEHKKDDISNLKTKVDCGVDFLTTQMF
FDNNIFYNFLYRIREKGILVPVLPGIMPITNKKQLRRSMELSGTAVPQRFLAIIDRFGDD
PEAMKQAGIAYATDQIIDLIANGINHIHVYSMNKPDVAAAIMNNLSAILKVED
>A0A369BGX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobacterium chartisolvens|TrEMBL
MKIIDLLKSKKPVIAFEIFPPKPDVPLENILSSLEKFKALNPDYISVTYGAGGSQKGRTI
EIASRAKKEYGIESMAHFTCVGHSYEEIDKMLDEMLDEGLENVLALRGDPPQNQPDFDFS
KNIYRHASELIRHIRGKNNFCIAAAAYLEGHPECRLLKEDLLNLKLKVDEGTDFLLTQFF
FDNRLFYDFLDKAESKGINCPIIPGIMPIFNSNIKVMTAKSGCSIPAKLVVMMDKYADNP
EDLRKAGIEYAAEQIRDLIAYGAPGIHLYTMNRPKSTKEILVSAGLA
>A0A518UAD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denitratisoma sp. DHT3|TrEMBL
MTKQISFEFFPPQTLEGMEKLRKTWEALESLNPTYFSVTFGAGGSTRDRTLETVLQIQRS
GLSAAPHLSCIGATRDSLGNMLEDYRSAGVSRIVALRGDLPSGFVAPGEFRHASELIQFI
RHETGDFFHLVVAGYPEVHPESKSNRDDIENFVRKVEAGADSVITQYFYNVDAYIQFVDQ
VRSRGVHIPIVPGIMPISNFEKIVRFSDACGAELPRWMRKRFDDFENDAESVKAYGLDLV
SDLCRRLLESGAPGLHFYTLNQSPLVAEICRRIGVA
>A0A261D214|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia sp. 1138|TrEMBL
MSSQLPQTSIVQRLAEPHPGPVPFSVEFYPPRDEQAEARLWRAVRIFERMGPAFVSMTYG
AGGSTRDRTLRIVGQLARETTLLPVAHLTAVGHSVEELRAMVGGFADQGITNILALRGDP
PGDPLGEWVKHPEGLEYAEQLVRLVQELGDFNVGVASFPEGHHRAPDLDHDTKYLVSKLR
AGAQYSITQMFFDVDDFLRLRDRVVAADPEQGAKPLIPGIMPITSLASVRRMVELSGSVL
PADIDRRLAAAAGGGPEEDREAVRAVGIDLATQMAQRLIAEGVPCLHFCSLNFAKATSEV
LERLGMNVMAA
>A0A1M7N546|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. KT 15|TrEMBL
MKITDHIKEANGKTLFSFEIIPPKKGNNIQELYNNIDPLMEFKPPFIDVTTSREEYVYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFSKEETEYVLVDCHYLGIDN
VMALRGDAMSHQKYFEPNKDGNHYAKDLVSQIQDLNCGKYLHEVVEASNKSDFCIGVAGY
PEKHLESPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVAAAKNAGINVPIIPGIK
PIAVKRHLQLLPQVFKIDLPEPLITAIEDCNNNKAVRQVGIEWAIQQSKELLAAGVPVLH
YYSMGKSDNVQAIATELF
>A0A848CEE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea formicigenerans|TrEMBL
MTCKIRDILKDQTPQVSFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKN
TVSIASHIKDDFGVTSLAHLTCVSSTREEVHQVIDKLKEKNIDNILALRGDIPKDNAFPL
PNQYRYACELIEDIKQQGDFCIGAACYPEGHVETEHKKDDISNLKTKVGCGVDFLTTQMF
FDNNIFYNFLYRIREKGILVPVLPGIMPITNKKQLRRSMELSGTAVPQRFLAIIDRFGDD
PEAMKQAGIAYATDQIIDLIANGINHIHVYSMNKPDVAAAIMNNLSAILKVED
>A0A6V7JMN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bracon brevicornis|TrEMBL
VDAGASFILTQILFSSQSFLQFVKNCRACGIKIPIIPGIYPITNYNSFLRLEKICQLTAP
KEIHRALEEIQDDKIKITNYGINLATNIAIEILSSGLAHGFHLYTFN
>A0A2J8KXB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pan troglodytes|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQL
>A0A0R2SDW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium BACL18 MAG-120924-bin36|TrEMBL
MKVTDHIAAANGKTIFSFEVLPPLKGNTIDSLFGTIERLMQFGPKFIDVTSHREEYIFKK
HESGLLQKVHTRKRPGTVGICAAIQNKFHIDTVPHIICGGFSREETEYALIDLHYLGIDN
VLVLRGDALKSEGSFVPEPHGHAYAIDLLRQVKNLNQGKYLYDEVQNSNPSNFCIGVSGY
PEKHFEAPSLKADLKHVKAKVDAGAEFVVTQMFFNNDHYFKFVDDCRALGITVPIIPGLK
PLTAKGQLQSIPRNFHLNLPDDLIEAVEAAKTPEAVKQVGVEWCIAQSKELMDKGVPVLH
YYTMSKADETEQIASALF
>A0A4S4CNS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus sp. KSM4-11|TrEMBL
MTARPETRISVELVPRSRSGLRAEIAQVVASLPGVDTVNVPDLTRYSLRSWLGCSYARPY
HRAVPHLRAVDFNPREALPFLSSLDEHGITEVLVVTGDAPADMSARVYDQDAVDLIRRVR
RDAPHLTVYAGLDPYRQSFARERDYLERKLDAGATGFFTQPFFDLRVMDAYSDLIPDGAQ
MWWGATSILTESSLNYWRARNHAVFPRTFTPTLECNRAFAADLLRFARERNQHAYFMPVK
VDVLAYLEGIL
>A0A1H9CAV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium urocaniciphilum|TrEMBL
MKVTEHIEKANGKPLFSFEILPPLKGQHIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LENGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGINN
VVALRGDAVKSEIYFKPEKEGHAFASELVSQINDLNNGIYLDSDLQNTNKTNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNQKFFDFVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMAVVKAKDNEAVKQIGIEWCTQQSKELIAKGIPVLH
YYSMGKAENIKAIASEVF
>A0A1X3DFX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria dentiae|TrEMBL
MLSSKQRKKLSFEFFPTRTPEGRAKQVITRKQLSQFDPEFFSCTSGAGGSTKEGTMQAIQ
DILSEGVAAAPHLPCVGMQPQEIINLLNEYKSLGVRHIVALRGDIPSGMGAGLGGLRYAN
ELVSLIKTEFGSDFHIEVAAYPEYHPQARSAEDDLNNFVRKAKAGADSAITQYFYNADAY
FRFVDDVHGRGVDIPIIPGIMPIASFSKLARFSDTCGAEIPRWLRLKLQSYADDTASIKA
LALDVVTDMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>A0A6C7E8M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ilumatobacter coccineus (strain NBRC 103263 / KCTC 29153 / YM16-304)|TrEMBL
MELGACPKSMRYGPCGGVRTGGGCEVVDEPCPFVGRPLVEWAGTELAPRAIELPRFLVDH
RPTGDDRVDRQVLDDYAASGVAVLLGDHLDDPPAVDRVAAAERTVDAGVPTIATITGRDR
STDERAEMIDGLLAAGVAAVLCVTGDHPSARFTAHPDVTFVSEGTLLAGEVRSRGGRVAV
AESPAAEPTRQRAARLVEKQRAGADIAVLNHSGPVADVIAFAEQASALGCRLPMYAPVPV
MTDLASMAALEQFPGLTIADDAVNAMHTSSDPFSTGLDLAVAMAGELLGSGSIAGVNLSG
VATSGGAVERGRVMRRVVDAVTA
>B1XSH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter necessarius subsp. necessarius (strain STIR1)|TrEMBL
MELSVEFFPPKTPEGESKLHLVRERFTEMLKPTFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVREMLKQYQGLGVKRIVALRGDLPSGMGQYGEFHHASELVEFIR
TETGDWFYIVVAAYPETHPQAKSPASDVDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YGLGVTQPIIAGIMPITNSSQLLRFSDACGAEIPRWIRLRLQSYGDDIASIRAFGEEVVT
DLCDQLLTAGAPGIHFYSLNQADAVLAIADNLDLTK
>A0A4S0Z4Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.163.01.1.1|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAARLKDYDPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIEFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLVEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A011PAM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter sp. BA-94|TrEMBL
MITTSPTFSLELFPPQTPEGAEKLRAARAQMALLRPKFFSVTFGAGGSTRDRTLETVLEI
QHEGHQAAPHLSCIGSTRASIRSILEQYRAHGIRHLVALRGDLPSGMARPGSFRYANELV
EFIRSETGSWFHIEVAAYPEYHPQAKSPLDDLLAFKRKIDAGADSAITQYFYNVDAYSHF
IDECQAVGIHAPIVPGIMPISSFSSLARFSDNCGAEIPRWIRKRLESYGDDKASIHAFGL
DVVTQLCERLLAAGAPGLHFYTLNQVGLTRTLWQRLGLASAAGD
>A0A374IKL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. TF08-4|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPD
AMKQAGIAYATDQIIDLLANGVNNIHIYSMNKPEIAVAIMNNLSEIIKC
>A0A517KZP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Venturia effusa|TrEMBL
MEKITDKLAALPKDGSYFSLEFFPPKTTAGFANLQARLERMSRALRPLFVNVTWGAGGST
ATKSLELAELVQRQLGLTTCLHLTCTNMSKSLIDSALERAKAIGVRNILALRGDPPRNEE
YFNKEDLDEESTEFVRAMDLVKYIRKQYGDYFCIGVAAYPEGHSDQSHPDHQDPKHDIPY
LVEKTKAGADFLMTQLFFDVKAYEKFEDMLRNDPSGVFKTIPIVPGLMPIQSYQILRRTT
KLSHARLPPDILERLDAVKGDDEAVKAAGVEIISEIIEELQARPHIGPRGFHFYTLNLEK
SVSQIVERCHLIRDMDAMDEDDSALEMSNDISIEINGQPRRQRLSSVHSDHRNKVITDRP
AGHLNPEYETMEKEAGLPTDGATRATTLQISEGEGSLGREATWDDFPNGRWGDARSPAFG
EIDGYGPSLHVSTAQALKLWGCPVTIDDVSNIFRRHIAGDLEAIPWSEDGLNPETATIRE
ELLRLNAKGWWSVASQPAVNGIKSADEIFGWGPRNGFVFQKPFVELFLPAADWEKLKRKF
EAYPDEITFFAANLAGDFESTDTKSVNPVTWGTFPGKEIVTPTIIEAVSFRAWAEEAFSI
WREWQRIYPPRSATAKLLGGIREGYWLVNIIHHAFVDQDGLWKLLLE
>A0A505H6R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. XM-20-01|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTQAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWIAHPEGVRYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVDSDTAYFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAATGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFERVADDPEAVRRLGVEQASEMCEKLLDEGVPGIHFITLNRSPATREVWQRLR
AAARV
>R6YN77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. CAG:732|TrEMBL
MNIAEFLDKEGDKKGFSFEVLPPLKGNGTAALFRTIDSLKEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQDKYDIPVIPHVICSGASKEDIEYELLDLQFLGISN
VLLLRGDKAKEDRQFAPTPNGHAHATDLLKQVAQFNEGFFADGTPIKHPGEKFCYGVACY
PEKHEEAPNLEMDMQHLLEKQQLGASYAVTQLFYDNEKFYQFVEKARQMGVTIPIIPALK
PFAKLSQLTVVPKTFHCDIPEALAQEVLKCKTDEDAKALGIEWTTAQVKDLFAHGYNNVH
FFTVSAVDSVKQIAKTLF
>A0A015LK38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus darwinianus|TrEMBL
EHVAAIAAALAGYSPQPAEAGQVTDGSSAAIIAPAAVAPAVPAGSAAPQTGAQPEARRAA
ADGGSPDGFGPSIVELVRERHTVIVELDPPRDLDIRKFMDGAAALKSAGVDAVTMADNSL
AVTRMSNLALAAIVKERTGLRPLVHIACRDRNLIGTQSHMMGLDALGIDHVLAVTGDPAR
FGDLPGSSSVYDLTSFEMIRMIKQLNDGTAFSGKPLKQKASFVVGAAFNPNVKYLDKAIQ
RLERKIESGADYIMTQPVYDTGLIARIAELTRHLPVPVFLGIMPLASGRNAEYLHNEVPG
IQLSDDVRKRMAGLEGEAGRAEGVRIAEELLDAAVEHFNGIYLITPFLFYDMSVQLTRYV
LDKTGRQATV
>A0A4S0Z046|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.163.01.1.1|TrEMBL
MNARQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPVHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWQREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A538SI60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium|TrEMBL
MSPGDGRTRSPGRTHLSHPFLRRLEKGVVLADGAMGTLLYDRGITFDRSFDLLNLQEPAL
VQSIHRDYIRAGAELIETNTFGASRIRLAAHGESTDARRVNRAGAQLARNAREEVGEAVF
VAGAIGPLGKPVAPLGTITREEALEVYVEQVEGLVEGGVDLLIIETQTDLEEMKLAIQAV
RKVTDLPLIAEMTFTEDERTLYGAYPEDVVRATQNLGVNVLGANCSVGPQKLLEIVQRLR
RRTELPISVMPNAGLPRFVSGRFLYLASPDYFADYAVRFQAAGANIVGGCCGTTPAHIRR
MRDALARPGAKAAEEIAADRAAAPPPLPTVHPEELPSADPASRSLLARKLANKEFVVSVE
VDPPRGARPKKMIEGAQFLKASGVDVINVADSPMARVRMSSLALASMISQQVGVETILHF
TCRDRNLMGIQSDLMGAHALGIRNVLALTGDPPRAGDYPNTTAVFDVDSVGLIRVLKQLN
AGSDLAGNSIGEPTRFLIGCAVNPASEDLETELERFQKKIEAGAEFT
>A0A847P3Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp|TrEMBL
MTSISIELVPRNHQEIKAQISEIKKLFPEVDTLNIPDLLRFPIRSCEACQYGLPVFKNVI
PHLRSIDFNLRERFELTETFINTGIKNVLVITGDKPQDMSKKVYRNTSLELIRVLKKEMP
ELKVFSGIDQYRSSLSKEIDYVKDKLEAGVDGFFTQPFFSAGDLILTEF
>A0A6V8QTT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma asperellum|TrEMBL
MDKITDKVAALPADAEYFSLEFFPPKTQMGFSNLRVRLQRMERALRPLFVNVTWGAGGST
AQKSIELAELCQRELGLTTCLHLTCTNMSQAMIDQALEDARALGIRNILALRGDPPRAEY
RDADEPTGSEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPYLV
DKVQAGADFIMTQLFFDIKAYEKFETTLRNHPSGAFKTIPILPGLMPIQSYAMIKRTAKL
SHAEMPEEIMARLNAVKGDDEKVKMVGVDILSELIEQIREIKSRTPGPKGFHFYTLNLEK
SISFILERTKLIPDVPEDEEAIVDESVPVAATGQRSIPRISVNGNVPPRQSRSHSRTARR
QSSVGSDPHNRVIVGRAATHPEWEATSTEAGVPAESINTRANTLAISEGEGALGREATWD
DFPNGRFGDARSPAYGEIDGYGVSIHMSVTQAVSLWGHPKTASDINDIFVRHIRGEISAI
PWSEEDLLPESFIIKSSLEAMNKKGWWTVASQPAVNGLPSNHATFGWGPASGFVFQKSFV
EFFIPSADWKILYDKLTSEENEELVCFYASNANGDFVSSDTTGGTGRATVNASTNAVTWG
VFPGKEIVTPTIIEEVSFRAWSEEAFDIWAEWAKVYGRGSDSEKLLNEIGQDRWLVNIIH
HDYVDTDALWRLLTN
>A0A321L5Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriia bacterium AA117|TrEMBL
MAQDLLSRLKQGPVLCDGAMGTLLYAKGVYINKCYDELNLIQPDLIRNIHQEYLNAGAEI
IETNTFGGNSIRLARHGLADKVREINVQGARLAREAADAFNFKKATSVLVAGSVGPLGIR
IEPLGKTSRDEARESFREQIIALVEGGVNLLILETFGYLEELHQAFLAARDVAPQLQVVA
QATIDEDGNCLDGATSETFAAKMTEWGADVIGCNCSVGPVAMLEAIERIRRVTPLPISAQ
PNAGIPRSIEGRNIYLCSPEYMASYARKFVNAGVSLVGGCCGTTPEHIKAMKAALRAADV
KGKTAGFPVVTERKHESSLTPPPLAQRSALGKKIAMGEFATMVEIVPPKGIDFRKEIAGA
RYLKEAGIDAINIPDSPRASARMSNLALCILVQQQVGIETILHFTCRDRNVLSMQSELLG
AFSTGIHNLICITGDPPKLGNYPDATAVFDVDAIGLVNIVRNLNSGLDIGGNPIGTGTGF
IIGVGANPGIVNIDEEVRRFEYKVEAGADFAVTQPVFDIGLLENFLRRIEHCRIPVLAGI
WPLVSVRNAEFMKNELRVSVPDAIIERMGRAPNAEAARAEGIQIAREMLNQVRGLVQGAQ
VSAPLGRYSSAIEVLEIESPASAGR
>A0A2H9P208|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon CG_4_10_14_0_8_um_filter_34_8|TrEMBL
MAIIYEVNPPKIPDNETPDDEIKSSIEKLMQRVSDISALCDGIHVTDSVLGTKRVSALTV
GRLLKKKHPDLQITISMRVRDKDMSLIKQLTQESIELKLDGILILKGDPSKENPTDSGLI
PSQVVKELNELGYGNKMNFFLSLPSNPNFEKIQKKIAASPKGFMTQVIHSAEQVQRISNK
LKPKGLRIIPCVLLPSEKNNNSAKFLELDWSNYKENPSNFIKQIHNIAGDVLVTSPNDFT
FAKETLKKI
>R8Y370|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus ANC 3811|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKYEFAGYPAAMTLADRVHSDHDITPLEASKS
YPDSIDKVLHFSGKARDIQDFEHFLEEAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHIYSQQILACVMPLTLGRANFMVKHKVAGIVITAHMLKVLADEKLAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLKLEALEELWNSLWQVT
TGKEFAPEIARFSRQPTSKQLIKYRQLHVMHEALFESKIAKGVGRFIFKAFFWENALVAK
VLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKALKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A3B9HP23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Riflebacteria bacterium|TrEMBL
MCPNLTTGEKQLQDFREFIEKNIVIFDGAMGTRLYEKGVYINRVYDELNLSQPALIQEVH
REYLAAGAMVLETNSFGANRFKLEPHGLADKLEVINFQAAKLAREAAGDNAWVAGSIGPL
GIRIEPWGKTSVEEAEEAFTEQARGLLAGGVDIFILETFFDINEIHQAIKAVRKLSDKPI
IASMTINEDGNALYGTTVDVFTPKLESWGADVIGLNCSVGPKTMYDAIEKMRALTRLNLI
AQPNAGLPRVVDGRMIYLCNPEYFGEYARRFFQLGVRMVGGCCGTTPEHIKWVANSAKAL
SPGGKGAILHQFRQVESVEEIVEVVPLSQKSALGKKLAENKFVVTAELTPPKGCDPEQVI
RRAQQLKEAGIDAINIPDGPRASARLSPLAMSLLIEQKVGIETILHYCCRDRNILGIQSD
LLGAYAIGLRNILAITGDPPKVGNYPQATAVFDIDAIGLVNVIHRLNHGRDLGNNAIGRP
TGFVCGVGANPGAIDLDLEVSRFEWKVDAGAEYVITQPVFDVELLERFLERISHVRIPVF
AGIWPLASLKNAEFMNNEVPGASVPEPLLQRMRKADTIEAQREEGILIAREALERVRKIV
NGVQVSVPFGRVESVLKVIEVLG
>A0A558CPL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis rhizosphaerae|TrEMBL
MDFAKSVRDRVLVCDGAMGTMLHTAGNSLDRALSELNLSNPELVSMVHEAYVAAGADILL
TNTFGANRLRLAGQGCSAAVRDVNLAGVRLARQARRGAGRPVFVGGSVSPAASVGQRGSV
RSGERAEVIGEQVRALVDGGVDLLVLETFGYLDELVEAVEVAASLADVPILAQATFTEAG
ETLGGETVGEVARALESMPVAALGANCTAGPQHMLAIVEDFRRHTVLPVGVQPNAGLPRR
RGTRFEYIVDGEYFGRYGRRYVEQGASIVGGCCGTTPAHLRALTRALADLRPVEPVRAQP
ARRTVAVPRHGVLARHLAEKDFVVAAEFTGETDDVTGLHEADLLFLGPAVSVNEALELAR
KAGIETVATVAAWDRAITTLQADLLGAHAAGLRTLVCETGAPPPRGEYPRGGWEVDSLGL
IELLAGLNAGRDHNGHTLAIRTSFHIGARFNPGAHDVDAELARTRAKIAAGAHFLVTRPV
YELDRLTGMLAELSEEDIPVLVTVSPLTGYAEAEYLTHEVPDVTIPRAALAALENTAHGP
ETGLALAADLVARARETVQGVVIRARGGMPRSLLRA
>A0A7X7NDH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp|TrEMBL
MIDLISKMTEQPLIFDGAMGTVIYDRGIFINTCFDELNLTNSKLIQKIHSEYVEAGAQVL
ETNTFGANRIKLAAFGLATKVDEINSAAVRCAREAAGDDIYVIGSVGPCTKSSEILQSAS
INEVQEAFREQIASLVKAGVDGIILETFSKLDELDLAIKAAESFDVPLIASFTVGHEGLT
ITGTPATAIVDFLDQNKRVQAIGINCGTGPAGAFSTLEKVISRSHKPFIVMPNAGMPRDV
GGRMLYLSSPEYFTTYAIRYIELGARGVGGCCGTTAAHIKMMSRSIKTMSGVKKYIEVKS
HKTDAAPVSMVKPSDKSRFAAKLLSGQKVTSVELLPPRSIDMSGVLEKAKLCAEKGIDVI
NIPDGPRASTRVSPMITAIAMLRDAKIEPVLHYCCRDRNLIGMQADLLGAYAAGIHNLLI
ITGDPPKLGDYPDATGVFDVDSVGLTQAVTNMNRGIDVGSNPVNPPTGFFTGVGANPCAV
DMDREMERFRRKVDAGAEFIITQPVFDVDALFRFLDKARNITQIPLVAGVWPLTSFKNAE
FMNNEVPGVVVPQSILERLKKVTTKEDGARMGTEIAMEIIDSISTRVSGFQISAPFGKVE
LALAALGK
>A0A6N8VNB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Holophagales bacterium|TrEMBL
MRFVVKLIDKLRSAIADERPFYSFEYFPPKTEAGIENLYARIERMGRLEPAFVDVTWGAG
GSTAELTFELANTIENVLGLETMMHLTCTNMPRRRIAAVLDDCRARGIGNILALRGDPPR
GRGAWSPIADGFSHASDLVRFIREEHGDHFGICVGGYPEGHPEAPSRGRDLDHLAAKVET
GADFVITQMFYEPELYFRFLEDCRDRGIDCPIVPGLAPINGYQSFLRITGFGASAPPEIV
SEIEARRFHDASVREYGQDLLTDICRRLLDGGAPGLHFYTLNLERSVQVILDRLGIVPER
VERVLPWRSATAVGRPKEDVRPIFWANRPKSYLARTQDWDEFPNGRWGDAGSPAFGDLGD
HHLAFRPISADLARERWGRELHSIDQVREVFAGFCRGDVDGIPWYDWPLDLESEPLRNAL
VRLNLAGLLTINSQPRVNGAPSDDPAVGWGGAGGRVYQKAYLEFFVAPEQVSPLLAALDR
KPSLTYHAIDRSGTAYSNCDTVNAVTWGVFPGEEVRQPTIVDPRSFEVWKDEAFDLWLSS
WAAVYEEGSESRRLLQRIHDTYFLVNVVDNDYIDGDLLAYLIEAAQADEPPSMTIVAPVT
>A0A7K9MWM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanodroma tethys|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPDAESYEADLRHLKEKVSAGADFIITQLFFRSETFLT
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEELEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A562TFH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga japonensis|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPAFINVTYHRSEHMFKKR
GDGSFEKVEIRKRPGTVGICAAIMNHYNVDAVPHLICGGFSREETENALIDLNFLGVDNV
LVLRGDAPKNETFFEPHPDGHRYALELLQQVVNMNNGVYLEEDLQEGVKTKFCIGVAGYP
EKHFEAPNMQTDIAHLKRKVEKGADYIVTQMFFDNQKFFDFVTKCRDMGITIPIIPGLKP
ITSKKQLTVLPRTFHVDIPDELSTEILKCKTDKEVEEVGTQWLIQQSRELKQFGVPVLHY
YTLGKPKVVKRVVEAVV
>A0A257SEM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium 21-71-4|TrEMBL
MGVNPAAADLEHEVKRFEWKVDAGAEYAITQPVFDVEQLERFLARIAHVRIPIIAGIWPL
VSVRNAEFLANEVPGVSVPEAVITRMRRANERSRDHAVAEGLAIAREMLDRVRDALQGAQ
VSAPFGKVDLALDVFGR
>A0A1T5FED8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizorhabdus histidinilytica|TrEMBL
MTSVPLSQLEEARRALDTPLFADLAGDAAVSFEFFPPKTEKMEETLWSAIQTLAPLRPRF
VSVTYGAGGSTRERTHHTVARIAGETAIPAAAHLTCVEASKAEIEEIAREYWAAGVRHIV
ALRGDPPTEGARFTPHPDGYRNAAELVAGLKAIHPFEISVAAYPECHPEAESFDSDIANL
KAKFDAGATRAITQFFFSPEAYFRFCDKARAAGIEGEIVPGILPVSNVAQTRKFAGLCGA
AIPAWMDRLFEGLDDHPAARQLVAATVAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHL
LGLRAKADRLENAA
>A0A520TA61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnobacter sp|TrEMBL
MLRQTNNSVNEKTMMNISFEFFPAKTDEGAEKLRATREKLSERKPEFFSVTFGAGGTTQD
GTLSTVLEIKAAGEEAAPHLSCVGSSKEKVAALLKQYKEHGIKRIVALRGDLPSGMLETG
SFRYASELVEFIRQETGDHFFIEVAAYPETHPQAKSPAADVDAFVHKVNCGANSAITQYF
FNLDAFLYFRDQVQHRISIPLIPGIMPVTNFSQLARFSDACGAEIPRWMRNRLQHFGDDR
ESIRAFGLEVVSNLCEQLIREGAPGLHFYTMNNAQPTLSILDQIGY
>E8XL62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium (strain 4/74)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A128F1R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grimontia marina|TrEMBL
MNFESGSVDRKPVLHDPAFAAAELIKNASLEATPKQIASLGDEKPDWLADGMRVYVPFLP
SAKFEDAFVACEILKKWGIEPVPHLPARAVPNEQALRLWLLALQALGVTQILLIAGDIDD
PKGPFTDTLQLMELGLFQEFGIDGIGVAGHPEGHPIVSEAVLVDALKRKRDYALQHGLSL
WVVTQFSFEQTVLEQWLEDHQTILEGIPVYLGLAGPTRLKNLLSYAAQCGVATSAKALTR
NLNAARLLRPWTPDSLLKAMAEFQSERPESVLKGIHLFPFGGLKQSSEWLVKKA
>A0A0G9LAH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. C8|TrEMBL
MNIKNLFNEKEVVFSFEIFPPKQESKIDIIYNTLEELKDLKPDFISVTYGAGGSLSKNMT
CEISSVVKKKYGIEALAHLTCINSTKTQVDYILNNLKESGIENILALRGDIPSNYDGISE
FNYASDLISHIKKRNDFNIVGACYPEGHLNTVDLDTEFKILKKKQDSGATHLISQLFFDN
EYFYNFLDKTNEYNIDIPIQAGIMPVINTKQIKRIVSLCGAKLPKKFIKIMNKYEYNPEA
LRDAGIAYAIEQIIDLISSGVDGVHLYTMNNAYVAKRISTNIFSILDTINNCEKVIN
>A0A3A6P249|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacter sp|TrEMBL
MSQAYFSIEFFPPKTPEGVEKLRTERAELAALGAKYYSVTVGAGGSAMYGNNDTVAEIQK
EGLEAAPHFLCIGSTRESVSKRLQEYKTQGIKHLVALRGDLQSGSDDVHGEFHYANELVA
FIRQETGDWFKIDVAAYPEMHPQAKSLPDDMNNFVRKVKAGADMAITQYFYNADAYFRFV
DDVRKAGVTIPIVPGIMPITNYAQLARFSSMCGAEIPRWIRLKLESYGEDLDAIRDFGLD
VVAELCQRLLAGGAPGFHFYTLNRAGPTAAIWQRLSLSDKV
>A0A401XA48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter pasteurianus NBRC 3299|TrEMBL
MSLSRLSVELIPRSAEALAADVATVKAHFPAADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQPGLEEILVVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMQGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLEANIQFAQTVLKELAQEKGKAYLMPVRIKLEQY
LPALLDAVA
>F3ZJ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Tu6071|TrEMBL
MASGTASTWTSEHPTVAEVLASGKRSYSFEFWAPKTPKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRTGTVRATQAIAENTTLVPVAHLTAVEHSVAELRHMIGQYADGGVRNILAVR
GDPPGDPLGDWVAREDGLTYAAELVRLIKESGNFCVGVAAFPDMHPRSENWDSDVRYFVD
KCRAGADYAITQMFFDPASYLRLRDRLSAAGCETPVIPEVMPVTSVRQLERLSRLSTAVF
PETVKERMLAAKDDPAAVRSLGIEFATEFCARLLAEDVPGLHFITLNNSTATLEIHENLG
LPHHRP
>A0A423Q1F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinisphaera japonica YTM-1|TrEMBL
MREDVSHNDFSIELFPPKGPKGAARLEDALAELGALNPAFFSVTFGAGGTTRSGTLDTVK
TAMRVTGRPAAPHLSCIEGTQASIGELLDNYKTAGVERIVALRGDLPEGMDKPGVFNYAN
ELVAFIKDRHGDDFHLEVGAYPEFHPTAPSPEADIDNFIGKIRAGADSAITQYFYNADAY
FNFVDEVSARGVDVPIVPGIMPITDFDQVSRFSAMCGADIPRWVRQKMEGYGDDKASVRA
FGRELVYNLCEQLLAGGAPGLHFYALNKSQPTATLWQDLKLPTGESDAA
>A0A0D0KZ38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MTNTNTDRHATESFKLSFEFFPPKSADMDVQLWETVEELSRWNPDFVSVTYGAGGTTKAP
TLQAVQRMISVAGLPTASHLTCVDASKQEVHDVVAEFRGAGVKHFVALRGDPSTGVGTDY
KPHPEGYENAAALVRGLRELGDFEISVSAYPEKHPESESDAVDIDMLKRKADNGATRALT
QFFFDNDIFERYMERVVKAGITIPVVPGIMPIQNLTQLKRFASRCGTSVPSFLDDRFAGY
DDDVVGRAKVSADVAAEQILDLQRRGINEFHLYTMNRAPLVNAVLDNVGYRPLRRSAA
>A0A3G6ITA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium pseudopelargi|TrEMBL
MPSIPARYQRPITDVIADTPPGLVPFSVEFMPPRDDAAEQRLWNAAVDFHDLGAAFVSVT
YGAGGSSRERTLRVAKKLAQHPLTTLVHLTLVNHTVEELQQILRDYADAGLSNLLALRGD
PPGADPLGPWQKTEGGLEYASDLIELVESLDATKHFEVGIATFPEGHFRCDSLEQDTEMT
VRKLRAGAEFSITQMFFDVDYFLRLRDRLVAYDPEQGAKPIIPGVMPITSIRSVKRQIEL
SGATLPDSLRRQLLEADERAKITGADEVRKVGIEITTQMVDRLIREGVPDVHFMTMNFAR
ATQEVLHNLGMAPAWGTELGHDALR
>A0A6N8CSR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrilactibacillus tamarindi|TrEMBL
MSNLLGALKERILIGDGAMGTFLYSFGIDRCFEELNLTHSEDVKHVHEAYIQSGSDLIQT
NTYGANYIKLSRYGLEDDVRKINTQAVKIARDAAKDKAFVIGTIGGVRGFKKQTLTLEDI
KRSFREQLYCLLLAGVDGLLLETYYDFEELKTVLDIARRETDLPIISHVTMHEPGTLQNG
MSLNEALHHLADHGANVVGTNCRLGPYHMIQALENVALPKNAYLSAYPNASLPDYEDGKL
VYQTEPDYFKKYAVDFRNEGVRLLGGCCGTTPEQIRAFKEGVQSLEPIQEKKVKVKVETI
ELEKSPSDTTLFSKIKNGRSLIVEFDAPRHLDTKVFFDGSRALKEAGADAVTLADNSLAS
PRISNAAIATKLQNEYDVPTLVHLTCRDRNLIGLQSHLMGLHILGLHDILAVTGDPTKIG
DFPGATSVYDVSSIQLIELIKQFNEGVSFSGKSLKGRTSFRVAAAFNPNVRNLDRAVARM
ERKIASGADYFITQPIFDPNRIVELSEATQHIKAPIFVGLMPLTSSRNAEFLHNEVPGIQ
LTDQAREIMAKVAGNKEQSAIEGVQIAKELIDVAMEHFKGTYLITPMMRYDMTVELTKYV
RTKESHQGGVSRANTFA
>A0A838Q1X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euzebyaceae bacterium|TrEMBL
MQATVRELLATGQPSFSFEFFPPKTDDGWNQLWRAIRELEPLQPTFVDVTYGAGGTTRDR
TVELVRRIAEETPLTVVAHLTCVSATVAEIRDVIDELGAAGIRNILALRGDMPGDPLAAF
RSTPGGLDYAEDLVRLLKESGDFCVGVAAFPEKHREAPDLDTDTKFLAQKCAAGADFAVT
QLFFDAVDYVALVQRLRRLGCDVPVIPGIMPVTNVRQILSISKLSGAAFPPDVERRLYAI
QDDPEAVRAIGVDVATQLCRQLLAAGAPGIHFYTLNRSTATRQIYESLQPHLA
>A0A2S0QA64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nodularia spumigena UHCC 0039|TrEMBL
MQDTQNPTVLNSFRRAAQAGEFLVTAEVAPPKGVDVTHMISMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQNGIEPICQMACRDRNRIGLQADLMGAHALGIRNILALTGDPVKV
GDHPHAKAVFDLESVRLLQLIRKLNQGVDDNEKPLPDGETDLFAGAAVDPQSDSWSGLQK
RFERKIEAGAQFFQSQMITDFERLEKFMDTVAVNYEKPILAGIFLLKSAKNAQFINRYVP
GVNIPQHIIDRLAQAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIAPILDLAGV
TPVTNVN
>S2JSN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor circinelloides f. circinelloides (strain 1006PhL)|TrEMBL
MKVVDKINKAENEGRTYWSFEYFPPKTDMGVQNLYDRMERMQRYGPEFVDVTWGAGGTSA
DLTMDIVATSQSVYGLETMMHLTCTNMPVESIDTALKAAKACGCQNILALRGDPPKGQLN
WESCENGFSHAVDLVRYIRKNYGDYFCIAVAGHPEGHIDNEDKEDDLLRLKEKVDAGADL
IVTQLFFDVDVFVQFVKRCRDIGITCPILPGIFPIQSYAGLKRVISFNNNAVPQKIWDDL
ESIKDDDQAVKDYGIDLAVQYVHQIKEQTGINGFHIYTFNLERSSRLILEKLGLVPEQEH
VKPLPWNPSLGPNRTKETVRPIFWKNRAQSYIQRTESWDEFPNGRWGDARSPAFGEFDRW
GVSIKYPVEKRLAMWGEPQSPDDIALLFAKYCKGKLEGLPWSAQKLEPETDTIKQRLAAI
NLLGYLTINSQPAVNGAKSNHPVYGWGPKNGYVYQKAYIEFFIPPSKLDELVQKIGKDPE
VTYFAVNKNGDLRTNTVDDEPNAVTWGVFPGKEIVQPTIVEPTAFMAWKDEAFGLWNEWA
HTYDRQSLAAEVILDIYENWYLVNIVHNDFQDENGIWRLFDLEIDGDLSKKLRRGSGSL
>A0A431NFG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MTTRPTDSRTAFADAVRRAGYEVLPFPSAHDKVLAHVPVEVPLTVTTTEAKGLEPTLDLA
VRLRAAGYRVAPHLAARLVRDKEHLTDIAARLGEAGVDRLFVIGGDAVEPVGVFPDALSL
LEALGDTGYSFGSVGIGGYPEGHGRIPDAALAQALRDKVPYATHVVTQLCFNAATTTRWA
ARAGLPVHVGVPGAVSRQKFIRVSAGLGLGQSARFLAKQQSMFWRFFLPGGYRPDRLLDC
LAPAFTGPLAGIHVFTFNDLEATEAWRQQLLARLS
>A0A2I2M646|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum dicentrarchi|TrEMBL
MKVTEHIKKSKGKTLFSFEIIPPKKGNNIQDLYNNIEPLMEFNPPFIDVTTSREEHLYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIEN
VMALRGDAMSHQRYFEANKDGHQYATELVGQIQNLNNGKYLHDVIEANHKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVEAGADYVVTQMFFDNQKYFEFVKHARKMGITVPIIPGIK
PIAIKRHLQLLPQVFKIDLPQNLITEIELCKNNQQIRELGIAWAIAQSQELLKAGVPVLH
YYSMGKSDNIKAIAKALF
>G9Z1U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yokenella regensburgei ATCC 43003|TrEMBL
MSFFHANQREALNQSLAEVEGRINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRAELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A2C5YUT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cordyceps sp. RAO-2017|TrEMBL
MHIKDMLAEAADGRQPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIA
QLTCDMVLQAQSVYGLETCMHLTCTDMGRDKVNDALNKAYKAGCTNILALRGDPPRDQEK
WTATEGGFQYARDLVKHIRSTYGNHFDVGVAGYPEGCDDNKNEDELLDHLEDKVSMGASF
IVTQMFYDVDNFIRWVGKVRERGIAIPILPGIMPIATYSSFLRRAKHMQCKVPKAWMDAL
NPVKNDDVAVREMGKTLVAEMCRKLLRNGIFHLHFYTMNLAQATRMVLEELSWAPSPERP
LHHALPWKQSKGLGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDARSPAFGELDA
YGIGLTGTNEANRKKWGEPITIHDIANLFVRYLHQEIDSLPWCESPLTGEADIIKQDLVA
LNQRGLLTINSQPAVDGVKSSHPVYGWGPSNGYVYQKAYLELLVPPETVDEMVRRIECRP
DLTFYAITKDGDLRTNATSDGPNAVTWGVFPGKEIVQPTVVESVSFLAWRDEAFRLGADW
AHCFDSSSPSRVLIEKLVSEWYLVNIVDNNFHENKAIFELLQDLEVKELNNPQTA
>A0A1M6DNJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dethiosulfatibacter aminovorans DSM 17477|TrEMBL
MNIIEKFNKKDKVISFEIFPPNKTMTLKQLLDVIDELALFRPDFISVTYGASGNANSNYT
IDIAQYIKEKYTIEAMPHLTCITSTKDKIDEILRSIEEKKLRNVLALRGDLPTDPNFKFP
DPLHFQYASDLIKYIKSSKYDISAAAACYPEGHMDCDSLDKDIDNLCKKVEMGADFLITQ
LFFDNEKYYTFKDKLSKKNLSVPITMGILPVTNAKQIKRITTLSGASIPAKLDTLLKKYE
NDNKSMMEAGIEYACRQMEELNEFGVDGFHLYVMNKPEVAKKIFKNMNW
>B2TWD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1V4PMX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. AT1|TrEMBL
MEFGPCGGVRLDGQCEMLPAPCVFDDAVPWSGAVAEPIPVPAPLILGDFSCSPFDAADVV
ATAGILARSCDAVLVGEHQNRPDFPPTIMGGLLLETGVTPWITLSCRDRNRIVLEQELRG
LAHVGVRTVFCVTGDGRGYDVRPDVTQTFDLDGPRLVALADSLGMVAAVPETPTAPPVSA
RPLRLVYKQRAGASLAVLNHVPSPSVAQEFVAAARAAGLTMPVVAGVAVFTDVVSAAVLQ
GLPGLELDERVVDDVLAADDPVEAGIEAAVTEARNLLSIDGVDGVNLSGSATARGTRFGA
EIKAEVGARIRRELGR
>A0A1Q8VC05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MRDNEPTDEPTSAAGSCGDGLSNAEPGTVRPLPTVSLELFPPRPGKAASATWGRIDRLLA
TGPDFVSVTYRPTFVSDPAGGNSDGGHEGSPSKPAAGRCDVAPRVRVAQERTNPSEYVLA
HVLESSTIPLMAHLTCIGYCKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRADDVAGELR
HADDLVRVIREVEADFFGDGRRHVTIAVAAYPAANDHIEAIEVLAAKQAAGADLAITQVF
YDAADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPESLRSSLGSASGA
TLVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRD
AVDRGYLQATPGRGPSFLRCGTPGAALSSRHPVQPHTTITKENA
>A0A1Q8HXY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MHDNEPTGPTAAAGSRGEALSSAETGTARRLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPAGGVTGGGRRGSEHEPEAGRYEAAPRVRAVQEQTNPSECVLAH
VLDSSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRAEDVAGELRH
ADDLVRVIREVEADFFGDGRRHVTIAVAAYPATNDHIEAIEVLAAKQAAGADMAITQVFY
DAADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPTGLRSSLGSASGAT
LVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDA
VDRGYLQATPGRGPSFLRRGSARAAVSSHHPVQPLITITKENA
>A0LTK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidothermus cellulolyticus (strain ATCC 43068 / DSM 8971 / 11B)|TrEMBL
MSTGRLIPAPGRSPTIRELLARGGSSFSFEFFPPKTADGERALFQTIRALEVLRPTFVSV
TYGAGGSTAAATVRITERIATETTLTPVGHLTIVNQSVAEIRRVIGQYAAAGVRNILALR
GDPPGNPNGEWIPHPHGFRYAVELVRLLKMVGDFCVGVAAFPRKHPRSPTLEDDTRYFVE
KCRAGADFAITQMFFRVEDYLRLRERIERAGCTVPIIPGVMPITSIGQIERFALLSGDEF
PPELADRILAVADQPAAVRAIGIEVATEMCRRLLDEGAPGLHFYTLNRSTATREIYQNLR
LSERADRHGKASVSGPGVAPSDVAGIAAGEA
>A0A850AC18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineales bacterium|TrEMBL
MTTDFRTRLESGLLLCDGAMGTEIYARGFSFDQSIEELNLTQPDAIKGIHRAYLSAGADV
IETNTFGANRIRQESFGLADQAAALAAAGVRLALEARAEAGKPQALVGASLGPLGRPLTP
YGNLSHESAAATYQEVIAAVAAAGADLLVFETFNDLAELTLAVRSARSLCDLPIVAHMTF
NEDGRTELGHTPEGVALALAELGVDAAGANCSVGPAVVLNVIERMHQAAPELALSALPNA
GFPSRSGGRLFYPSTPEYFASYVERLAAAGAQIVGGCCGTTAAHIAAMRGAVDGGARRVD
PIASFEIELDLPATRPETRPAATALAQQLGQTFIATVEMSPPRGYTPTRLLDQAQALRQA
GVTAINITDSPRARMRMSPWAAAFLVQSRLGMETILHFPTRGRNLLRVQGDLLAAHALNI
RNLFIVMGDPTAIGDFPDAYDTYDIPPSGLVQLIKQHLNQGVDQAGQPIGAATNFFVGAA
VNFGAEDLARESKVLERKLAGGADFLLSQPIYDPEVVTRFLAHWGGPLPVPVIAGLLPLV
SVRHAEFLHHEVPGILIPDRLRQRLQHAADPEQEGVVIARELLAFLRDWAAGVYFMPPFG
RFHLVGDILQGSLTAGGD
>A0A510CZK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rochei|TrEMBL
MNPAVSAPAAVGTDLLDDFSLEMTGKDVPALEEARGSIPQGTRINVTFLAGEDHATRLAA
ARAVRGLGFVPVPHVSARRLPSSAALEEFLAGLAEDGTADNVFVVGGDPARPEGPYEDAL
AVLRTGLLERYGVRHIGISGYPEGHPAISGPALWSALTDKARAIGAGPFTGDVITQFGFD
ADPVLDWLAAVRARGVDLPVRIGVPGPAGIRRLVGYATRFGVTTSASVARKYGFSLTNLL
GTAGPDRFLHALGERYDPARHGVVKVHFYTFGGLRTTAEWVGGFRERTR
>A0A1F6CVG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kaiserbacteria bacterium RIFCSPHIGHO2_01_FULL_53_29|TrEMBL
MKVTDLIKNSSVPFTSIEIIPPRKGTSMETLFAELEVLMRYKPAFMSVTSHAHERSVEEV
DGKKVERMKHKRLDTNAICIAAQSRLGVEPTPHLICRGFTKDETEDVLLTLHFHGIENVL
ALRGDGPLADAQTAASFVNEHASDLVEQIERMNDGVYLDPVERAEKTDFCIGVAGYPEKH
FEAPDMETDLAYLKKKVDAGAHFIITQMFFDNEAFYRFRDDVARLGIQVPVIPGIKPLYK
KQHLEVLPRIFYTKIPQSVQDSINRFDKEEDIHRAGIDSTIAQCKDLLAHGVPGIHFYSM
SVAKPTSEVLNGLMA
>A0A1V2IDJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia asymbiotica|TrEMBL
MRDFLAAGETSYSFEFFPPKTADGERALWQALREIEALHPSFVSVTYGAGGSTRDGTIRV
TEQIATDTTLTPIGHLTAVNHSVAELRQVIGNYAGAGVCNVMALRGDPPGNPQGEWVAHP
DGLQYSSELVELVKSLGDFCVGVAAFPDKHPRSPDLESDADFLVGKFNAGADYAITQFFF
GADNYFRLVERVRARGCEAPIIPGIMPVTNVAQIERMALLSGADLPADLVTRLRAAADDP
AAVRAIGIEVAVDLSERLLAGGAPGLHFITLNRSSATREVCQAVRRGVAAP
>A0A257ZX72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. 12-68-7|TrEMBL
MMNAFRPSRHGSRRPKVSFEFFPPKTAEMEVSLWESVRRLEPLAPSFVSVTYGAGGSTRI
RGYWEAGVRHVVALRGDPAGGLGTVYEPHPDGYHQTSDLVAGLKRIGDFEVTVSAYPEKH
PEAASLEADIDALKKKVDAGATRAITQFFFDNDVYFRYLDKVRAAGIDIPVLPGIVPVQN
FKQTANFARKTGASVPQWLADRFEGLEEDAATRRLVAAAVCAEQVLDLIDRGVGDLHFYT
MNKADLVYAICHLAGVKPERGEAQAAAAE
>A0A1J7I0Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lupinus angustifolius|TrEMBL
MKVIEKIRAASSDPDRVVFSFEFFPPKTEDGVDNLFERMDRMVSHNPSFCDITWGAGGTT
ADLTLEISNKMQNMICVETMMHLTCTNMPVDKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQAEGGFACARDLVKHIREKYGDYFGITVAGYPEAHPDVIASDGLAPLEGYQNDLAYL
KSKIDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KVPADIMAALEPIKDNEEAVKAYGIHQGTEMCKKILSHGIKYLHLYTLNMEKSALGILTN
LGLIEESKIYRSLPWRRPTNVFRIREDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSNS
PSYGALTDYQFMRPRARDKKLVEEWAIPLKSIEDIYERFKLYCLGKLRSSPWSELDGLQP
ETKVINEQLEKLNTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKL
DALVIKSKDRLSLTYMAVNKEGAWKSNVSPTEVNAVTWGVFPAKEITQPTIVDPVSFKVW
KDEAFEIWSRGWAALYPEGDISRKLVEEVGASYFLVSLVENDYVNGDLFGVFADF
>F3SJR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis SK1087|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A510DB33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rochei|TrEMBL
MLAGGKTTYSFEFSAPKTPKGERNLWTALRRVEAVAPDFVSVTYGAGGSTRAGTVRETQQ
IVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGAWVAHPKGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVVEAGCDTPVIPEILPVTSVRMLERLPKLSNAQFPDALKERILAAKDDPAAV
RSIGIDFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLGLHHPPQA
>A0A1T4QBW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pilibacter termitis|TrEMBL
MKIEEIYQQRKNEKKPVISLEIFPPKKDSGIETLYQMMDDLKEVKPDFISVTYGAGGSSL
VENKTLELASFIKENYNIETLHHLTCVNKTKEEIDQIVKEIQKKGIENILALRGDISGEL
TVSDFPFAKNLIREIHQLGDFSVGAACYPEGHIDELCSQENTAHLLAKEQAGVNFFISQL
FFENERFYRLLENARAARIYTPISAGIMPIMSRKQVERMIFLCGASLPTELIKIIHKYEN
DLDSLRKAGLEYALNQADDLIQQGVEGIHFYSMNQSYVATSVLQRYGGEH
>A0A3A2HXC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. PID23_8|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWSSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKATTGLVAAPHLTCIDATRDELIDIADDYWNNGIKNIVALRGD
IPLGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDIVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQAVVEA
>A0A1V5UV67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium ADurb.Bin236|TrEMBL
MKSNSNLEKVFASGQLAVTGELGPPKGTNIKVIEEKAKHLKGMVDAVNLTDNQTAIVRLS
SIASAKILLDIGLEPVMQMVCRDRNRLAMQSDLFGAVALGVRNMLCLSGDHQVFGNHPQA
KNVYDIDSVQMINMVKTMRDEGKLLSGDEVDGEFKMFIGAAENPFGDPFASRVPRLAKKI
AAGVDFIQTQCIYDMERFKKWMEGARARGLHEKCFIMAGVTPLKSAGMANYMNNKVSGIS
IPEDIIKRMKGVPKEQQAEEGIKIMVEQIDELRKVEGVKGIHLMAIEWEHRVPELVERAG
LLPRPKFD
>A0A2R6HIH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QS_4_66_20|TrEMBL
MAQQSFSRSDGADALLRDARFELMPFDSFDDELTYLPDGATIAITTSPQLGIERTVERSE
QAAADGYEPVPHIAARYVRDGDHLEEIARRLTEAGVTEIFVPGGDREEPVGEFESAYQLL
VALDETEYSFEEVGITGYPEGHEFLDEQTLRTEMDKKAPYATFIVTQLCYDPEAVIEWIE
KIRGRGVDLPVEVGIPGVMKYSRLLQISRKVGVGDSVKFLRKTTGVVDFVRQIVGSRGTY
KPDELVDGLGPYADDEEYRISGIHIYTFNQTKDTEDWRRGRLQG
>A0A7Y0LAF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassotalea algicola|TrEMBL
MSYTHARQVESLNQSLSEIASDINVSFEFFPPNSAEMETTLWNSIERLAPLKPSFVSVTY
GAGSGTRDRTHDVIKRIQKETALVAAPHLTCIDAGREELIQIAKDYWDSGVRHIVALRGD
LPDSSEKPSMYASDLVELLKSVADFDISVAAYPEGHPEAPNPQFDLLNLKRKVDAGANRA
ISQFFFDVESYLRFRDRCVTVGIDVEIIPGILPVTNYNTLKRFAGLTNVHVPSWMPKMYE
GLDDDETTRRLVGANIAMEQVKVLSREGVKDFHFYTLNRAELTYAICHTLGIRP
>A0A7D7VG36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boseongicola sp|TrEMBL
MSAPSISFEFFPPQSLEASFRLWDTVQALSYLDPSFVSVTYGAGGTTRKLTHEAVCALHQ
QAGLDVAAHLTCVDASKKETLEIAESYAAVGVKRIVALRGDPPKGQGQFRPHPDGFSDTT
ELVSALTDSGNFDIIVGAYPDRHPEAQDDNADVEWLKRKIDAGASGAITQFFFDIETYQR
FRDRCADAGIFAPIIPGILPIENWQGVQKFAKRCGAKIPTETVQMFETAERDGRTDLLAT
AVCTELCTDLLDDGVNHLHFYTLNKPTLTRDVVHALGLAPKIALEKVA
>A0A4V6I321|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter trogontum|TrEMBL
MLESLVAKLRGNESFLSVEVSPRLSATIGQNVIDELESLEQADCFVCTDSPLARLKPSSI
LSSIKLQNALNKPLICTLSMRDRNSIALCGDILAANEFGLRAFLSLSGDSVKNGDCAGAK
GVFEESSLKLGRIIEDLNQGVAANGKALKDGVKPIYNFSVINSHANNTESLKKKMLKKLS
NSKVEGLFTQPVFSLQSAQFLLESLEEINENLEQKCVMILGFFPVLNYKVALFLRDKLPG
VYIPNEWVERLEKASIRSKEEEQKVGLELSRDLFFGLQALHNKFHFMSANKPSLLKEFVR
G
>A0A7Y3FCN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boseongicola sp|TrEMBL
MSRPTISFEFFPPQSLEASFRLWDTVNTLSPLDPAFVSVTYGAGGTTRTLTHEAVETLGQ
SMGLDVAAHLTCVDATRSETLEIAQNYARAGVKRIVALRGDPPKGAGSFQPHSDGFSDAS
ELVSALAETGDFEITVGAYPDAHPDAAYDGADIDWLKRKIDAGATNAITQFFFEAETFLR
FRDRCAEAGIEAEIIPGILPIENWKGTKRFAKRCGARIPATLSAMFDTAERDGRTDLLST
AVCTELCTELLEEGVNHLHFYTLNKPGLTRDVVHALGLAPDISLSKVA
>A0A847KFY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MSAWSAETAGGAARPVAVALRTRPRISYELYPPRRPEHRDRVWRVVTELVQTQPRCLSIT
YPSTAEGRAESRHLVTRLLAETTVPPVAHLTVVGTPRAQLVARVRALFAAGVRDFLALRG
DPEPGKPWQPHPDGLNYATDLVKLIRAVERDARAGGDLTGPVTIGVAVYPHAHGENRYRE
LVAMRAKQEAGADFAITQVFYDVREYAALVREAPSAGVSIPILPGIIPLTDPARLARLST
LTGIDLPSDLRELLDASEPAERFTRAIVATADLAEGALVAGAPGVHVFTFNQSAPALALF
EELRRRALIAP
>A0A7X4XW98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium halotolerans|TrEMBL
MGYSYASHLDALNQNIADLNGAINVSFEFFPPSSPAMEETLWSSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKEQTGLLAAPHLTCIDATRDELRAIARDYWKSGIRNIVALRGD
LPPQGGKPDMYAVDLVELLRAEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVVNMKQAKRFAQANNVKIPNWLEKQYQ
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAEAEAIA
>A0A5X9F9T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Tamberma|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A258TFW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. 28-66-16|TrEMBL
MRPSSALHPDWAVPTPTMITDGYSLEITAKDIDALRAAAPAIAERTPVAITFLPGETMDA
RIAAAVAVRALGFEPMPHLSARRIGSLAELEQIVARTTAEAGAERMFLVAGDPPQPAGPF
ADTLSLLRTGLFERHGIKAIGIAGHPDGHPAMDTAGLWQALDDKRADIAARGMATLIVTQ
FGFDADPFLAWLRELRDRGIDAPVRIGVPGPAGIKTLLRFAMHCGVGASTSVMAKYGVSI
TQLLGTAGPDKLVDNLARGLGPDHGAVRLHFYPFGGLARTVEWIGNHRAANRR
>A0A415H1I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. AF42-16|TrEMBL
MTLREKHKQGKFTITVELDPPKSSSAQKVFDQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNEGIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNGA
HFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A1J5SLY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MGNPPTPISFEFYPPQTPEGIEKLSAARQRLAAMKPEFFSVTFGAGGSTQDRTLEAIRQI
HAEGHSATPHLSCVGSTRDNVRALLFAYKDMGIKRIVALRGDLPSGMASIGEFQYANELV
SFIRAQTGEHFHIEVAAYPEFHPQANSAREDMLNFKRKINAGANSAITQYFYNTDGYFRF
VDECRKLGVMVPIVPGIMPITRFSQLARFSDACGAEIPRWMRKTMEGYGDDVESVQNFGL
DVVTQLCEKLIAGGAPGLHFYTLNQASASLEILKRLGYR
>A0A1J5QR36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MGIGHLSFEFFPPKTPEGAAKLAATRQRLYAHRPEFCSVTFGAGGSTQEGTLATVREIVA
EGVVAAPHLSCVGASRDSVRRMLLQYRDEGIRRIVALRGDLPSGYGLGGEFHHASDLVAF
IREQTGDAFHIEVAAYPEVHPQARSPQDDLSHFAQKMRAGANSAITQYFFNADAYFRFRD
DAYAAGIDAPIVPGIMPITGASQLLRFSEVCGAEVPRWIRLRLLSFGDDRAAIVAFGREV
VAGLCERLLRGGAPGLHVYTLNQPDATLALLDDLGSV
>A0A1Q7Y3W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium 13_1_20CM_2_69_58|TrEMBL
MPSAFSQRLDAGPLLCDGAMGTMLYARGVSLDACFDVLNLNNPRLVQAIHAEYVAAGADL
IETNTFGANRFKLAAHGLESQVREVNRRGVRLARDVRESTGRDVLILGSVGPLGKYLAPL
GSVTAEDARAAFREQAEGLLEGGVDACIVETFSDLAEIALAIEAIRSVTDLPIVAQMAFT
DEGVTFTGRSPAEVGRTLRALGVQALGANCSVGSSTLYGVLEQMVPAAGSLPLAIQPNAG
LPSRVGERLIYLSSPAYMAEYAARMVEAGARIVGGCCGTTPQHIAAMREALDRQRPPRRD
AVRSTITVTAPVLRESAGLLTRRPATTLQRKLEAREFVVTVELDPPRGHTVEKLVQGAKV
LKERGVEIVDINDGSLGRVRMAVLPTALLVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALDVRNILALKGDPPRAGDYVSTTAVFDVNAIGLIEVLKRMNQGLDATGNSIGLPTSFCV
GAALNPGAENIKAEISRFHRKVHAGAQWLQTQPVYDLAELDRFLEQAGGPPVPVIVGVLP
LHSYRHAEFLHNEVPGITVPEQIRARLRDAGDGALRVGIEMAQRLVREIRSRYAGVYLMP
SFGRFEVVAEVLDALH
>A0A7K8M9E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ptilorrhoa leucosticta|TrEMBL
MVNETQYTCSASSSSRSDGGSSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGD
KWFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAV
NYCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVD
LVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFL
KFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNY
GVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKR
RVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREEL
LKMWGEELSGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRR
GILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVN
YHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAK
LYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7T3RCA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema peruense|TrEMBL
MKITNILKEKKVLLSFEIFPPKQQANFDNVVSAAKELSALNPDFMSITWGAGGTTKGNTV
EIASKLIDFGTPALAHLTCVGNTKNEVEKVIAKMKANKIENVLALRGDIPQNSDSGSVLT
EGLTHASDLVRILKDHGMCVGGACYPEGHPESANRQDDMDNLMYKVDSGVDFLTTQMFFD
NNMLYSYLYRLQSRGIHVPVFAGIMPITNSSQVSRMIKLSSAYVPAKLLSICDKFEYKPE
AMRQAGIAYATDQIIDLITNGVRGIHIYTMNKPSIAEDILKNIDSIIKASNEL
>A0A356D5I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia sp|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSEEMEQTLWKSIDRLKNLKPKFVSVTY
GANSGERDRTHSIIKDIKDKTGLIAAPHLTCIDASRDELRGIARDYWNSGIRHIVALRGD
LPDNSRKPDMYATDLVELLKAEADFDISVAAYPEVHPEAKSAQADLISLKKKIEAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLDRFAKMTNVRIPSWMSRMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>G4YYD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora sojae (strain P6497)|TrEMBL
MKIIEKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMAEADIKKALDQAKDAGIHNILALRGDPVRGATS
FDECDRGFSHAVDLVRYMREHYGDHFCIGVAGYPEGHMESSDKKADIQYLKEKVDAGADF
IITQLFYDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTSFCNTFVPEEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLLSLSSRVPR
RELPWQTSTLSKRAAETVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSSTSTPNERRAMWGEAPATKEDIRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGALSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
PSVQYHAVNLNGHSYSNASKSAIAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEDGSQSAKLLREVHDTYFLVSIVDNDFVNGNIWDLFEASVSPATSP
>A0A2U8SVI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MSTSPRPSISFEFFPTKTDAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDTKAELRELLNLYKDAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEVAAYPEMHPQARNFEDDLANFVRKARAGANSAITQYFFNADCY
FYFVERVRKLGVDTPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A1Q4NUR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia marcescens|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLRDIATDYWNSGIRHIVALRGD
LPPGGGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDVETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A1F8IDL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacterales bacterium RIFCSPHIGHO2_01_FULL_67_30|TrEMBL
MAASSTNLAEARALLLSPLGPVARAGSNHDAVRVSFEFFPPKTDEAEANLWTAIRRLEPL
NPAFVSVTYGAGGSTRERTHRTVQRIIAETSLRPAAHLTCVEASRDEVDEVIAGYKTIGV
DHIVALRGDPPGGGGIGGVYQPRADGYANATELTAAISRVGGFDVTVGAYPEKHPESPSI
DHDIDVLKAKVDAGATRAISQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLTR
MCGACGTSIPDWLKAHFDGLDDDPETRRLLAASVAAETCARLHEEGFSDFHFYTLNRADL
VYAICRVLGVREQKAAA
>I4IXB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa PCC 9701|TrEMBL
MTTRLQRAVQDREFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQIACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGRLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMRQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDMAGIPPIHN
>A0A0D7DZ37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MTALNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLTNFVRKARAGADSAITQYFFNADCY
FYFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQA
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A7C1DU54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
METRTPSKLEKILAASHLAVTSECGPPRGSDPEAITRKAAMIKDHVDAINVTDNQTSVTR
LCSLASCIHIKLMGLEPILQMVCRDRNRIALQSDILGAASFDIFNMLCLSGDHQRFGDCP
GGQNVFDIDSMQLLQTVRYMMDDGKFLGGDDIKRPPRMFVGAAANPFADPFEIRVPRLAK
KVAAGAEFIQTQCIYN
>A0A7V1UQI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MLVRDILDKTNISFSFEFFPPRSEKAWERLFQTIADLMPLKPSWVSVTYGAGGSTRENTH
NLVVRIKRETDLTVVSHLTCEGSDKKEIESILANYCDNGILNILALKGDPPADQRKNENV
CSDFVHAVDLVKFIRRYFPEMSVGVAGFPEGHPDTPNRLKEIEYLKAKVDAGADYIITQL
FFDNRDFYDFCERCELAGIRVPIIAGIMPVLTLNGMNRMAEIASGSRFPASLIKSVVRAD
IDKYVEKAGIHWATEQVRDLIDNSAKGIHFYTLN
>A0A857MDB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia amarae|TrEMBL
MPYDVPVTTNSTSLSIVDRLSAPHRGPIPFSVEFMPPRDAEGEERLWRTVRTFERLGPAF
VSMTYGAGGSTRDRTVRITGQLASQTTLLPVAHLTAVNHSIDELRSLVGAYAAQGITNIL
ALRGDPPGDPLGEWVRHPRGLTYAEELVRLIRDLGDFHVGVASFPEGHHRAPDLEQDTRA
LVDKLRAGAEYSITQVFFDVEHYLRLRDRLAAADSEQAAKPLIPGIMPITSLASVRKMVS
LSGSVIPVDVEARLAAAAGTGDQEDRAAVRAVGIDLATEWAQRLIAEGAPCLHFCSLNFA
KASTEVLARLGVDITSAVPVVAG
>A0A853GB31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Vesicomyosocius endoextente|TrEMBL
MKISFEFFPPKTEQGKEKLIQVRQSLSVVSPKYFSTTSGAGGKTQDTTLEAVLDIQKNNN
IPATPHLSCIGLKKSNIIELLDKYKAININHIIALRGDIPSSIRNMGDFHYANELVEFIR
SKYNDNFNIEVAAYPEMHPQAKNIESDLTHFVNKVKAGANGAITQYFYNADAYFRFQDDV
QKLGINIPITPGIMPITNYTKLLNFSNMCGAQIPKWILERLKFYENDLESLNDFGFDVVA
NLCQTLKNQGVNSFHFYSMNLVEPSLKLAKNII
>A0A6F9BLB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coregonus sp. 'balchen'|TrEMBL
MVNNVQRVDDTWRTCTKSDSSGASNSGGESSKESSRSSTPVLDADSMDRLRDKMRRRTES
GDHWFSLEFFPPRTANITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQTKE
KITGYLSKAKRLGLKNIMALRGDPMGADWEVEEGGFNYATDLVKHIRCEFDDYFDICVAG
YPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFGYQSLRQLVKLSKLEVP
EEIMRVIEPIKDNDAAIRNYGIEQTVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLG
LWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAF
GELNDYYLFYLKSKSSKDSLLKMWGEELTNEQSVYEVFTSYIKAQPNRAGHKVMCLPWND
EPLAPETNLLMDELDKVNRRGVLTINSQPSINGKPSDDPIVGWGPPGGYVFQKAYLEFFT
SSENVTVLLKVLKKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDP
VSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVID
NMFELLDNPPEEQPTEQPAEQPAEESPVEINPQSNCGDSQTD
>A0A7C4R1D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLEKILRAGHFAFTGELGPPRGAHAEEVRKKAAHLKGRVDAVNITDNQTAVVRMA
SWAASLILIQEGIEPNYQMVCRDRNRLAMQADILGAAALGIRNMLCLSGDHCLFGDHPTA
KGVFDLDSIQLIRMVKQLRDEGKFQSGADVDGRPAIFIGAASNPFADPFEWRVQRLAKKV
EAGVDFIQTQCIYNMAKFREFIRLANEEGLTEKVFILAGITPMKSLGMAKYMKTKVPGMD
VPDEIISRLQGVPRDKQAEEGIRIALEQIAELKAMKGVHGVHLMAIEWEHRVPEIAERAG
MLPRPLVG
>A0A7X1H393|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSVKTPSKLEKILSEGHLSVTSECGPPRGSDPDAIKEKAKLIKDYVDAVNITDNQTSVTR
MSSLAACIHLKLMGVEPVLQMVTRDRNRIAIQSDILGAASFDIFNMLCLSGDHQSFGDCP
QGQNVHDLDSMQLLQTVHLMRDESKFLGGADIKRPPRMFVGAAANPFADPFEIRTPRLAK
KVAAGAEFIQTQCIYNVDKFVEWMKLVCDRGLHEQTYILAGVTPLKSAGMAKFMKNRVPG
MDVPDDVVKRMADTPKEKQPEEGINICIETIERLKSVEGVKGFHIMAIEWEEKVPGIVER
AGLYPRPKID
>A0A367GLS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter hurinus|TrEMBL
MKITEHIENANGKTLFSFELIPPLKGQSIQGIYNAIDPLMEFKPPFIDVTSLREDYIYKE
HQNGLLEKLSYRKRPGTIAICAAIMNRYKVDTVPHLLCGGFTKGETENALIDLQFLGIEN
VLVLRGDARRGDATFIPTEGGHCYATELLQQVVNMNNGKYLHEDYEGIEKTNFCIGVAGY
PEKHFEAPNLKADFKYLKQKVDMGANFIVTQMFFDNQKYFDFVNGCRANGINVPIIPGLK
PITNSKQLSSLAKTFFIDMPEDLCDVINACKDEKAVREAGIEWMINQCKELIKFGVPVLH
FYTMSNAGPTRKIAEAIF
>A0A0R2PNQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium BACL15 MAG-120823-bin78|TrEMBL
MVSRTSYSFEFFPPKDVEGEDRLWAAIEGLKAIAPDFVSVTYGAGGSTRDRSIRIAREIT
QRTGISTVAHLTCVGSTRQELLTILQSYKDAGITSILALRGDPTGGPSAPWTATENGLNH
ADELVQMAAEFGGFTIGVAAFPDGHPASNGDFDKDVDVLIRKEQLGATFATTQFFFEADR
YTQLVNKLRARGSKLTIIPGILPVTNVKLLHRMAELGGTPIPRNIADAFAQIENDPQAVR
ALGVEIATSLCKELLAAGASGLHFYTMNSSTATQEIYRKLNDAQ
>A0A1F8MRV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_53_26|TrEMBL
MAKSLFEEKLYSREFLVTTEIGPAKGADVSEMIHHVDLLKDKVDAINITDHQSSVMRFPS
IGGCLLVKERGGEPILQVTCRDRNRLALQADLLFAHSRGIHNVLCLTGDSIDVGDHKEAK
PVFDLDSVQLLKMARTLESGTDFAGNQLKGAPQFCLGASVHPEADFIEPQLLKFDKKVAA
GAQFFQTQGIFDLSSLRRFMQYASQFNVKILAGIIVMASARMAKYMNENVPGITVPQAVI
DELATAEKGKGLQKGVEIAAKIMRTIGEEKLCHGVHIMAVGNERVVPDILEAADLVSVRA
>A0A1G5CKM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium XBB2008|TrEMBL
MIPLAATRQYSLRGTYKPPAINKDRREIMKIIDIIKQDKLSLSFEVFPPKKESSYESVRV
ATEEIAKLKPAFMSVTYGAGGGTSKYTLDIARNIKDRFNIPMLAHLTCVSSDRETVKERI
AQMQEAGIENVMALRGDLTPELENTDRSKWDYRYAYELIKDIKASGADFCIGAACYPEVH
PESATQWEDIDHLREKVECGVDFLTTQMIFDNSLFLNFMYKIREAGIHVPVLPGIMPITK
ANQVERAIKLSGSFMPHRFNSLVDKFGSDPEAMTQAGIIYATDQIIDLYANGITNVHVYS
MNKPEVAAGIMRNLSDILGKNFEGR
>A0A2A3ZKA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MSQEVLASLLKSARYEILPTAGVVDRVHEYVVPGRVITVTASTGLTLEATLSTAEQLQAL
GFTAVPHIAARMVQGRTELEEIVDRLTQAGIDRIFVPAGDATPPAGGYAGALDLIIDLAS
MAAPIQHLGVGAYPETHPLIPDDVTVQAMWDKRDYATHLVSNLCFDPGTIATWLARVRAR
GIDLPLVLGIAGKVELAKLARVATKIGVGESTRFLRKNTVTFTKMAKPGGYNPRKFLDKL
APVLDNPSMGVAGLHIYTFNQIKDTEIWRRRQLAALGHNDEVPSTS
>A0A317SMI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tuber magnatum|TrEMBL
MVHIAPKLVAEHKGNGKPTFSFEYFVPKTAQGVQNLYDRMDRMNQLGPQFIDITWNAGGR
LSNLTCEMVNVAQSVYGIETCMHLTCTGMPKSKVDNALKEAYKAGCTNILALRGDPPREN
EKWEADPHGFHYAKDLVKYIKANYGNHFDIHVAGYPEGCDDGTDPELLLEHLKEKVDAGA
SSIITQMFYDVDIFLDWVNKCRDIGITVPIIPGIMPIHTYAAFMRRATWTKCHIPEKWLH
LLEPVKNDDVAVRDIGRDLMVELCQKIIDAGILHLHFYTMNLATATRMCLEGLGIIPSLE
QRTKALPFRPSLGLNRKEENVRPIFWKNRHMSYVQRTQEWDEFPNGRWGDSRSPAFGELD
AYGIGLRGSNEANIKIYGYPKTIRDLGELVKQYLTGNLPSLPWSEGYINSEADTIRDELL
KLNERGFLTINSQPAVNGAKSTHPVYGWGPKNGYVYQKSYLELLVSPEHLAELITRIERD
PDLSYHAVDKNGTLKTNSSEGPNAVTWGVYPGKEIIQPTIVETISFLAWKDEAFRLGDDW
AKCYEAESVSRHLIQGVMDTWFLVNIVDNDFYRGEKIYRLFDGMEVPNMDESLADGLTSA
>A0A1L9QF34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium AO1-B|TrEMBL
MTDSSLLANGRLPASTEMSPKQVVEKTELLAAIPAGSQVYVTDLGNAPEDTIVAAAKTLT
DKGLTAVPHMAARRYASVTDFERRITRLTQEAGVKEVLAIAGEADKAGPLTSSVALLETG
LFDKLGIQKIAVAGHPEGAPDIKSDVIKSFLMRKHELAADSDAEFRIVTQFGFDPHQVSV
WLDEIRSWGNQFPVHIGVAGPAKMTTLLKFAAFAGVENSLNFLKKRGGAVVSMLAGYDPN
TMVEPLEARVTSQPDSQLAQIHVYPFGGVAKTAEWLTSRGSWSFQTSSTSLTANESA
>A0A1M5D5B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio gazogenes DSM 21264 = NBRC 103151|TrEMBL
MGYSYAGHIDALNQNISELSGDLNVSFEFFPPSTPQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLVTAPHLTCIDASREELSQIADDYWNNGIKNIVALRGD
IPPGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKADAGANRA
ITQFFFDVECYLRFRDRCVSAGIDVEIVPGILPVSNFNQAYRFAAQNHVKVPGWMSKQFD
GLDDDPVTRQLVGASQAIDMIRILCREGVKDFHFYTLNRAEMTYALCHTLGIRPQA
>A0A3D6BWX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MNETVTSQSRLERILTSGRLAVTSECGPPRGSDPSAVREKGRLIKDHVDAVNVTDNQTAM
TRMCSLAACIHLKQEGIEPVLQMVTRDRNRVALQSDILGAASFDIPNMLCLSGDHQSFGD
CAQGQNVHDLDSMQLVQTACHMRDQGKFLGGADIKRPPALFVGAAANPFADPFEIRIPRL
AKKIACGAQFIQTQCIYNIDKFKAWMHRAVDRGLTERAFIMAGMTPMKSVGMAKYMKTKV
PGMDVPDAIIKRLSGVEKKKQAQEGIDICVEHILELSEVPGVAGFHIM
>A0A3A4XAU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MRTECAGKLERVLSDGGFAVTAECGPPRGADSGIIRKKAELLKGFVDAVNVTDNQTAIVR
MSSIAACAHLTAMGIEPVMQMVTRDRNRIALQSDILGAYSLGIRNILCLSGDHQRFGSQP
DALNVFDIDSINLVRTVWTMREQGQDMSGFALKEAPRMFIGAAANPFADPFEYRVIRLAK
KIEAGADFIQTQCVYNMERFKAWMKMAREEGLTEKVHILAGVTPLKSEGMAKYMAKRVAG
MDVPESLIKRMGGVPKDKASEEGIQICLETIAELRNLQGVHGIHLMAIEWEEVVGRIVSE
SGLLPRPAAA
>A0A3A4RZJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MRVTDLYQGSKPVLSLEFFPPRNEKADKEFDGLIDKLSTLNPDYMSVTFGAGGSTRDGSY
QTVKKIMVDKHQPTVAYIAGYGLGPEEVTAVLDKYKDLGVETIFVIRGDKPKDDQFTPHP
DSFSYASEMIAFIRKHYDFTLGCAGYPEGHIEAKSLEEDINFLKNKVDHGAEYIVAQYFY
DNDYFFNYVKKCRAIGIDVPIIPGIMPVYSVKMTRMLSKVCGSRITDALQKRLDAVDADD
ANSVVQVGIDFAVEQCRGLLKEKVPGLHFYTMDRSESTMAIVQRLGQEKLLSCS
>C6BZ56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maridesulfovibrio salexigens (strain ATCC 14822 / DSM 2638 / NCIMB 8403 / VKM B-1763)|TrEMBL
MQVAQNINEAGQFFSFEFFPPKDKSTWPVFMERAARLAALKPLFASVTYGAGGTSHDNSL
EICSLLKKDMGIDILAHLTCVGASEQSIDEFVSRLCETGVSDILALGGDGVKDANGEGQS
RFFHASDLVEYVDDKFSEVGIAVAGYPGGHPESPSIAKDIEIHNSKLSKGADFTMTQLFF
DNRLYFDYVDRLAELGSTAPVIPGVLPIQSLSSLRRIMSLCGAGIPGDLYCGVEKAFEKG
GDEAVMEFGFDFARKQISDLLDRGAPGVHIYSLNRAAMCERLITDLKGDGYFN
>A0A8H4YCT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sp. NRRL 66182|TrEMBL
MHIKDMLNDAQKSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNEALLKAYKAGCTNILALRGDPPRAQDK
WIATDGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKVPQEWLDAL
EPVKNDDVAVRNIGKTLVADMCRKLLASGIHHLHFYTMNLAQATRMLLEELEWAPCAKRP
LKHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTVQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIRDELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPSNGYVYQKSYLELLVHPDVFDNMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYNTSSPSRALLEGIMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTEPV
SDDAVDIEPIASGTAVTAVAN
>A0A8H4V2L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sp. NRRL 66182|TrEMBL
MAQALRPLFVTVTWGAGGTTAAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQA
KALGIRNILALRGDPPRSEEYNVDGDDDSNKDFTWAIDLVRYIRKTYGDYFCIGVAAYPE
GHPGESQTDIQDPEKDLPYLVEKVQAGADFIMTQLTYDFEAYQKFEDKLRNHPSGAIKTI
PIIPGLMPIHGYKILTRVTKLSGAHIPPAIMSRIEQVRSDDERVNQVGVDIVSEIANQIK
ALPNPGHRGYHFYTLNLEKSVTLILERCNLIPPSSDDSAIEDGIAIEEVDSTNKDLKTWV
SRRRASSINSGPHNRVIVDKLHVPTDQQSEHSSRRSITYETLASSAGVPALNPPPRSTQL
QISEGIGSLGREATWDDFPNGRWGDSRSPAFGEIDGYGPSLHVNATVARKLWGFPVSRED
IGTLFRKHVSGELYIVPWSEGGAAEDANLNAETQIIKPQLLQIIEKKNWWTLASQPAVNG
>U3K671|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ficedula albicollis|TrEMBL
MLGLDIGFFNHLLPTPAVPALCRDPCTDHTPSAPLCRALTMVNETQHTCSASSSSRSDGG
SSSGSESSKDNSRCSTPVLDLDRHERLREKMRRRQDAGDRWFSLEFFPPRTANAAVNLIS
RFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDI
TGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDICVAGYP
KGHPEAESYEADLRHLKEKVFAGADFIITQLFFQPETFLKFMKDCQAIGITCPIIPGIFP
IQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGL
HFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRT
QEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFTCY
ITGEPNRNGYKVTCMPWNDDPLATETNLLKDELERVNRRGILTINSQPNINGKPSTDPIV
GWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNA
VTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYL
VNLVDNDFPLENCLWQVVEDTFELLNSPTQQ
>A0A851WVW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corvus moneduloides|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLRDKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFVITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7Z0DDY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium durum|TrEMBL
MHPHNIPANLQVPISRAISLRSPGQVPFSVEFMPPRDDAAEARLWAAATTFHDLGACFVS
VTYGAGGSTRERTSRVARRLAKQPLTTLVHLTLVDHTEDELRAILREYSELGLTNLLALR
GDPPGDPLGEWCTTNGGYSYANELIDLVHAMPECQHFDIGIASFPEGHHRARTLEDDTYY
TLAKLRAGAQYSITQMFFDVDHYLRLRDRLAAADPEHGTKPVIPGLMPITSLRSVRRQVE
LSGAALPSALEERLERAAAGDEEKNRDEIRKVGIEVTTAMAERLIEEGAPDLHFMTLNFA
RATQEVLHNLGMAPAWGTDAGQDAIR
>A0A8H6NRQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum musicola|TrEMBL
MDKITDKIAALPADANYFSLEFFPPKTTMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
SQKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALEDAKALGIRNILALRGDPPRKDE
YRDAEDSDVDDVDDFVYATDLVKYIRKKYDDYFCIGVAAYPEGHADESHPLGQSFEHDLP
YLVEKVQAGADFIMTQLFFDIKAYDNFEKILREHPSGAFKTIPLLPGLMPIQSYQMIKRT
TKLSHAKIPDNVMARLEAVKGDDEKVKQVGVDILSELIEQVREVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDHEEEDEVAVVDDAPGAPVPTFQLNGLSPVPAGTPRALSGRRQS
SIGSDPHNRVIVSSASNPAYETTAASLTAEPVNTRANTLAISEGEGVLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVTQAVGLWGTPKTVQDINQLFVRHIKGQLSAIPWSEE
ELLPESNIIQQELLELNSRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKSFVEFFLP
SADWAGLVARLNEVKDGSICFYAANASGDFVSSDASGGLVLEGAESSTNAVTWGVFPGKE
IITPTIIEEVSFRAWAEEAFNIWGEWAKVYGKGSESEALLERVRSEYWLVNIIHHDFVDR
DALWKLLRGEKEN
>A0A0Q9S6F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Soil796|TrEMBL
MRNKLDVGGKTRNQTMRRLLEQARYEVLPTESTEQKVVENVPLDRMITVTASPSKGLGAT
FDLAERLTGHGYAVVPHLAARMVSGRSELAEICERLTSGGITRVFVPGGDAEPAGDYPDA
LSLLEDLVALGRPFAHVGITGYPESHPQISDDMTVQAMWDKRRHATHIVSNLTFDPAVIK
VWLERMRKRGITMPLLLGMPGPVDRTKLLGMATRIGVGESTRFLAKHKGTFARLAAPGGF
TGERFLARCAPALGAPTAFVEGLHVFTFNQIAETEAWRTDLLQRL
>A0A3S5JDB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda sp. TMED12|TrEMBL
MKITDHIKKAKGETLFSFEIVPPVKGKSIQELYSNIDPLMEFKPPFIDVTTSREEYIYKE
KDGLLDKKLTRTRPGTLGICASLKHKYDVDTVPHVICGGFTKEETEYLLVDCQYLEIENV
MALRGDARKEEKYFTPTKGGHQYATELVEQIQNINQGNYLHDTIESSDLSSFCIGVAGYP
EKHMEAPSLQSDLKRLKQKVDLGADYVVTQMFFDNQKFFEFVETAREMGINVPIIPGIKP
IAVKRHLQLLPQVFRVDLPQDLIDAVEACKNNKEVRQVGVEWAIQQSKELREAGVPVLHY
YSMGKSDNIKAIAKELF
>A0A4R4VDW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora terrae|TrEMBL
MTSELRRSLDRMRYEVLPVGNARVEALDPGSTVTVTASPARGIGPTIDCTERLAAMGLRA
VPHLAARSIRDHAHLTGVLDRLDAAGVSEVFVIAGDAAKPLGEFTDSLALLRAMERMGRL
PARIGIAGYPERHAFIPDDSAVRAMSDKSHYADYVVSQITFDPGTIIDWAFDLRKRGVEA
PVYVGVPGVVDAHRLLRIALKIGLGESTRFLRKQYGAVSKMLARYTPEELLDELSPQLGD
PDSPIAGWHLFTFNEVTKTVQWRDDLAARLSGYADRPA
>A0A0G3GZ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium mustelae|TrEMBL
MAIIYKTMSAPIPARYQRSIVDVISATAPGRIPFSVEFMPPRNDEAEQRLWKAAEVFHDL
GAAFVSVTYGAGGSSRDRTMRIAHELARHPLTTLVHLTLVGHTESELIEILCDYANAGLS
NLLALRGDPPGADPLGEWQPVPGGYEYAEQLIKLTKRLDETSHFHIGIASFPEGHHRAPT
LEADTEFTLAKLRAGAEFSITQMFFDVEYYLRLRDRLARDPEQGLKPIIPGIMPITSLRS
VRRQLELSGAKLPAKLEERLLKAADGDESKNQEEIRKVGIEESTLMAERLIAEGAPDLHF
MTLNFARATQEVLHNLGMAPAWGPELGHDAVR
>A0A2G6KEW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB3 bacterium|TrEMBL
MRIKKLLDTQKTLLSFEFFPPKHDKGWDALFETVANLAPLNPSFVSVTYGAGGSTRQYTH
QLLNRLTRETDLTVSAHLTCVNSTQREIYEILEEYVKSGVDNIMALRGDPPQGEQAGTQF
TYASSDGFAHAADLVAFIKQHFPQLCVGVAGFPEGHPTTPNRLREIEHLQAKVDAGADYI
VTQLFFDNRDFYDFCDRCELAGIQVPIIAGIMPITSSNGMQRMAELAAGARFPAPLLRAV
ERVHAHQGKIAPIGIHWATEQ
>W2DZ54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FH1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKSAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQAHSFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITNMCEDLLNGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>J1LN16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. ICM47|TrEMBL
MPLPESFTVPFSDDDYACPCTHDHEPTLLSFEVMPPRKPSLEAPFWDTVDRLLQVRPDFM
SVTYGAGGKDRNNARSTVQRLVRDTPIQPIAHLTCVGNSTAEVVSTVHDYLESGVRTFLA
LRGDPPVGQEDWEPGPGGVASATELIHLIRTVERRRCNAHPGEALRSAFKPLTIAVAAFP
AGNPAAGTTPQQEVERLLVKQAAGASFAITQLFWDAEVYASFVERARRAGVTIPIVPGLL
PATDPARLRRVQDLTGIEVPEQLLTTLAGFEEQERRDEFGAAFGSCLIHSVLDAGAPGVH
LYTFNKAKPVLDILALMGVTPDPQWSPASHPFTHH
>A0A1N6XUE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. RU33A|TrEMBL
MTKPERPIAKTPDVRISFEFFPPKSPDMEDQLWQTVKALQPYQPDFVSVTYGAGGTTREP
TLATVKRLIDETPLATASHLTCVGATREEVRAVVEEFEAAGVRHFVALRGDPQGGMGSRY
APHPGGFLNAADLVSGLRDLGDFEISVSAYPERHPESENDDVDIDMLKQKVDAGATRALT
QFFFDNDIFERYLDRVRAAGITIPIVPGIMPIQNLTQLKRFASMCGSSTPSFLDERFEGT
EGDPKARAAVAADIAAEQIADLSRRGIEEFHIYTMNRAPLTIATLERLGISAKADKISNA
AA
>A0A0R1ZUP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus sharpeae JCM 1186 = DSM 20505|TrEMBL
MKTSELFKRDRPVFSFEVFPPRNFDRPNAEKRVCATMEVLREVNPDFVSVTYRGAGPDAP
KATIGIAKLIRDRYQTEAVVHLPAARLTKADVDDFLVRAEDAGIQNILALRGDIPEGGRV
SDDFHYASDLVTYIKSKGDFNVSGACYPEGHPESPDALSDIRALKTKVDAGTSELISQLF
FDNEAFFKFQDRCQFAGINVPIEAGIMPIMTASQAERMQAMAGVNLPAKLQGVLHRFADK
PDALRDAGIAYAVDQIVDLLAHGVDGIHLYTMDNPEVAARIIEATKNIIRA
>A0A8H9WYL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MRTWQKPSFRSLLQKTSIFVTCVELVNSRGVITERKGTRILKLARELSQNPQIHALCITN
NAGGNAMLSGDTLSTDLISRGQEVVIHLSCKDWNRNGLQSQAWKLASEGFNNVLALSGDY
PISGYQGQASAVFDIDSVGVLKMMSEMNAGLKISAGQKKKDRVLKQTSFFLGAVVNNHKQ
YEREVMPQYFKLKKKIENGASFIINQIGYDARKQDELLKYMDWSGLHVSVLANVYVLSLT
AARFFHANNIPGVTVTDDLLALIEKQAGSSDKGKTFFLEFAAKQCAIAKGLGFRGVYLGG
HLKSSDYERILEIADQFGEDDWKDFSKEICFHQTDEFYFFEPDTSTQLSSTEINREYLHS
KSLKALQVSKQNIPLSYKINRVVHDKAFEKGTLGFGLGKKTSQAIERTNKGVQKILHGLE
QTFKMAAFGCQDCGDCSLPDIAFLCPESQCAKNQRNGPCGGTYQGKCEVGEKECIWSLAY
DRLKAYGQEEQMLNGPAIFKDGSLKGTSAWINTFLERDHHGDGKKHGDGKKQMES
>A0A7W7GDD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerisporangium siamense|TrEMBL
MSLGRPSVRPDRVPTVRDLLAAGGRSFSFEFMPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSSRDRTVDAVERIAHETTLTPVAHFTAVDHSLRELRHLIGRFAGAGVRNILAVR
GDPPGTDPLAEWIKHPEGVAYAEDLVRLIRQAGDFCVGVAAFPYRHPRSPSIESDTEYFV
RKCRAGADYAITQMFFRAEDYLRLRDRVAARGCDTPIIPGIMPVTQMSTIARSEKLSGAP
FPPEVAARFEAVAGDPADVRRVGIEHAAELCQTLLDEGAPGIHFITFNKSSATREVYQAL
SPEPAVAKAG
>A0A7Y9L3Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. 1224|TrEMBL
MDNPNFSIEFFPPKTAEGAEKLRATRAKLAELNPKYFSVTFGAGGSTQRGTLDTVVEILA
AGHDAAPHLSCVGGTRESIRAILQEFKSHNIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGDWFHIEVAAYPEVHPQARSPQDDLLAFERKIKAGANSAITQYFYNADAYFQFVE
QVRKLGIDVPVVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTALCERLLQGGAPGLHFYSMNQAAATTALWQRLV
>A0A7W9B4K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis panaciterrulae|TrEMBL
MTSTLDSLAEARRAAASPLFADLAGDIGVSFEFFPPKTEKMEAQLWETFHTLEPLAPRFV
SVTYGAGGSTRERTHATVARIAKESPVPPAAHLTCVEASREEIDAVARAYWDAGVRHIVA
LRGDVPGGEPYRAHPDGYANAAELVAGLKAIAPFDISVAAYPETHPDSDCPQADLDNLKR
KFDAGATRAITQFFFSPDAFLRFRDAAAAAGIDAPILPGILPVSNVSQTRRMADMCGTSI
PAWMVSIFDGLDDHPAARQLVAATIAAELCRRLYAGGVRDFHFYTLNRAELSYAICHMLG
LRPTAPAKEKAA
>A0A7W6HWZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricimonas faecihominis|TrEMBL
MKVIDILNNTDKAVFSFELVPPLKGGDINKIYEAIEPLIALAPPFINITFHRDEVVYREY
PDGTIKKVTVTKRPGSVALAAAIMRRYNVDMVPHIVCGGATRHKIENELIDLNFLDIENV
MALRGDPIPGERFFTPEEGGHQYSCELVEQITRMNHGQYLDDTLTDAVPTNFCIGVAGYP
EKHYEAPNQACDIENLKKKVDAGANYIVTQMFFDNSKFFQFVDKCRAQGITVPIVPGLKP
ISTFKHLEMLPRTFSIDIPHELVKEIRSCKNNKEINQVGIEWCVAQSKELIAHGVPAVHY
YTMGKSENIQEIVKQVF
>A0A2E8RQ60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MSDFLHQIERRILIGDGGLGTQLRLRLPSNIRCLDACNIDPTFRNFVYEIHADYGRAGAD
IIQTNTYGANQLKLDLQGYGNQLESINHAGVQLASQAATEISSSQNRQVFVAGSVGPLES
NPLEDELSITEIRQAFTAQMEVLVSAGVDLLILETFTELRQTKIATKLAVKFGLPVIVQI
SGISKGIVSDGTDVRVFAQTLCQLGANVIGLNCRGPHDLLLAAEKIARVTDTPLSVQPNA
GTPRIDQGKIRTTYSVSPDHFSGFIKRFLSLGINIIGGCCGTTSEHISVIRENIADYVPT
RRQTQIFVFPDNQKSSKSNISPNPVRQIFETNDRIVSVEMRANTFPQLRAMVKASKNLAD
LGVDLFDVPDNAGATVNIGAIGTAFKLQQASNIPTLIHWTTRQRNLISIQSHLLEAWALG
IKGIIALSGDHPKVGRFETAKIVTDVRGSVQLMELLKRLNQGTLIDGTSLGEVCDFYVGG
GFTITKNLKPQLKHLRRKVERGAKFIYTQPVYDLSTAEDIYESVKNEGFETKILLGILPI
TSFRSISFLQDNLGMYIPSTVVKKFQDINNPEDQFLCGLSIATDLVSQLSEQNRFSVDGI
YIIPPSRINWAKKQATITQLVQSFRK
>A0A6L8F349|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MATTLRKKDNFMDALAHRILVCDGAIGTELRKRIPAYLQCVDACNISTEHAEKVTALHTA
YINAGADVIQTNTYQANREALAVHGLAEQVKEINTTGVLLAREAVSETSYIAGSVGQISF
HSLDTTVPSTKTIRQTFKEQMDALVDAGVDLLVLETFLSPKQAEVATKQALTYGVPVVVE
ISGVSGGTVGAGLDVRVFAQALEQLGANAVGINCRGPHDLVEAMELLAPVIKVPIAVQPN
AGNPRVEQGEVAVSYTVEAEVFSDYVGKLVELGANMIGGCCGTTPAYTAKIRQAIAGREP
VQRESRIFVLPKIRSVGARSSRPYDNPVQQVFETRKRIVSVEMRANTFPQLRAMLKEAKG
LAAIGVDLFDVTDNSGAAVNIGAVGTAYRLQQATQIPTLIHWTTRSRNLISMQSHLLEAE
ALGIRGIVALSGDHPKAGPYETASLVPDVRGAVQLMKLIARLNQGELADGSSIGEPCGFY
YGGGFTIAENLQPHVKHLANKVAQGANFAYTQPVWTYEDIAHAQQATEHLGLKMLYGILP
LTSFRSASYLRDNLGLYIPQFIVDKFRDLGDTAGQELGMRLCLELVRDIRNQDECEIDGI
YLIPPARMNWKNRARVISEIVKTYRE
>A0A1G3IK40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sideroxydans sp. GWF2_59_14|TrEMBL
MGNTTPISFEFYPPQTPEGVEKLAAVRQRLATVKPEFFSVTFGAGGSTQDRTLDTIRQIH
AEGHSAAPHLSCVGSTRDNVRAMLFAYKDMGIKRIVALRGDLPSGMASIGEFQYANELVS
YIRAQTGEHFHIEVAAYPEFHPQANSAREDMLNFKRKMNAGANSAITQYFYNADAYFRFV
EETRKLGVTAPIVPGIMPIVRFSQLARFSDTCGAEIPRWLRKTMEGYGDDNESVQNFGLD
VVTQLCEKLIAGGVPALHFYTLNQANASLEILKRLGYR
>A0A1H7HP41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas palmae|TrEMBL
MSTQAKEFRQVNEAVLAHDGPLYADVGGDVDVSFEFSPPKTDKAEENLWQSIATLQPLSP
RFLSVTYGAGGSTRDRTHATVARIARETDVPAAAHLTCVEATREELDAIAQEYWAAGVRH
IVALRGDAPAGADGYAPHPGGYENAAALVAGLRRLHPFEISVAAYPECHPDSIDAAADLD
NLKRKIDAGANRAITQFFFEPDTFFRYRDAAAAAGITAEIVPGIMPIASVAGVMRMAAMC
QTDVPAWLTRLFEGLDDRPAARQLVAATVAAELCRKLYAGGVKQFHFYTMNKAELSFAIC
HLLGVRAGGAAQAKVAA
>A4EZQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseobacter sp. SK209-2-6|TrEMBL
MAEFDMHLVVSLMLFLRIMKLSHNAARATSTEVNKYLDAVTQETRDMTPKISFEFFPPQS
LEASFRLWDTIQVLAPMDPRFVSVTYGAGGTTRDLTRDAVKTLHSSSGLNVAAHLTCVNA
SKAETLEIAENFADAGVKEIVALRGDPPKGAGKFTQHPEGFANSVELIEALAATGKFTLR
VGAYPDPHPEAPNAQADVDWLKRKIDAGADEALTQFFFEAETFFRFRDACAKAGIDGDKL
VPGILPIENWKGARNFAKRCGTHIPDWVENAFEKATRDDREDLLATAICTELCSDLLEGG
VNKLHFYTLNRPELTRDVCFALGITPKTVLENVA
>A0A5C6GJ08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium rileyi|TrEMBL
MDKITDKIAALPADREYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
ANKSLELAELCQRELGLTTCLHLTCTNMSKRLIDKALEDAKVLGIRNILALRGDPPRKQE
YHDAEDSEDDGTEDFIWAIDLVKYIRKKHGDFFCIGVAAYPEGHSDESHPQSQSSEHDLP
YLVDKVQAGADFIMTQLFFDIDSYDDFEKTLRQHPSGAFKDIPIMPGLMPIQSYQMIKRT
TKLSHARMPTAIMDRLDAAKGDDEKVKLVGVDIISDLIDQIRTIKSRTPGPRGFHFYTLN
LEKAVSFIVERTGLIPEDSDNEEALIIDDGTLAPPPIQVNGNRTSAHSRTSRRHSSVGSD
PYNRVIVAGQPPTHPEWEATAREAGVPADSINSRANTLAISEGEGVLGREATWDDFPNGR
FGDSRSPAYGEIDGYGVSLHMSVTQAVTHWGRPTSREDVIKVFVRHIQGEIPAIPWSEEG
LSPESSTIQSRLVGMNSKGWLTVASQPAVNGVSSSDRTFGWGPVNGFVFQKAFAEFFLPS
ADWHVLADKLKGSDYCDSVCFYAANVKGDLVSSDVGGGVSTRTVAASTNAVTWGVFPGKE
IVTPTIIEEVSFKAWCEEAFGLWEEWAKVYGRGSASEEVLRGIQSDYWLVNIIHHDFIDR
EALWTLLLG
>A0A374CB62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. AM42-24|TrEMBL
MNITEFLNNGAQEKGFSFEVLPPLKGNGTAALFRTIDALKEFNPRFINITTHHSEFVYKE
LDNGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHVICSGASKEDIEYELLDLQFLGISN
LLVLRGDKAKDDRQFTPTANGHMHATDLLKQVNQFNDGFFMDGTPIKHPGEKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNQKFYDFVEKARKMGITIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDEDAKELGIEWTTAQVKDLFEHGYNNVH
FFTVSAVESVKQIAKTLF
>A0A2N0KNA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Casp-Chloro-G2|TrEMBL
MAKVIERSFEATGHTSIMCDFSPPRSGDAAVVDQAQLDVDFISVSYNPGRAVRTDSAMLA
AAVQRSGRDALFTLATRDMNKLALQSQLLGAQMLGLNNVIVVQGDPFSEQDRTRVASVAD
YSTTGLIAAISQMNQGKDFRDGNLRTATDLCVGAAVDLGRGIEEEAQLAVRKVRAGAEFL
ITQPVFDVDQVARYRESYAYHAGKAGTLPIYFGLQILEQDGVLFSSVPDSVRNELEGGRP
GIDMALELYQRFQDARLNNIYLMPPIKRGGARDYAAAKELLAKINRL
>A0A222XG46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. PSBB021|TrEMBL
MNPPAAQPRLDDARADGASSAARPGVPTGAHVAADPRPLGTLDRPTLSFEFFPPRNPQAA
PRLWETVRQLEAVHPDFVSVTYGASGRTRETSRAFVSRLLRETSLSPIAHLTCVGTSRDE
ITTIVEEFLDEGVRSFLALRGDPPAGQADWQAHPDGLETASALVGLLRDIESRRCGASPA
QAVRARVRPLSVAVAAFPRGNAATGGTRAQDVASLLAKQEAGADFAITQVFYDAESYLGL
VAEARAAGVVIPIIPGIIPLTDPARLLRTQELTGVPVPRDLLDALGSADDASAAHRIGTR
AGVDLVKGVLDGGAPGVHLYTYNKHEAALDLLEGAQLDGSTR
>A0A2E3EY03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tistrella sp|TrEMBL
MMTVTTDGRVLTPRALWDAPAPVPGLKISLEFFPPRGAQAEARLWENVARLAAYAPDFVS
VTYGAGGSTRDKTRDTVLRMRRDYGLAAAAHLTCVDASRTDVMAVAEGYIADGIDHVVAL
RGDPPQGAGPYVPHPDGFPFAVDLVRALADLGRFEISVAAYPEVHPQAQSAGADLDNLKA
KLDAGATRAITQYFFDPAVFLRFRDRAAAAGITRPILPGLMPVLGFQQIKRFSAACGAGI
PDWMERLYDGADADEATHQAVSPMLLAEQARVLAAEGCADLHFYTLNKAELTISACHLLG
IRPRAEVAAARAAG
>A0A7U7IK86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia enterocolitica (type O:9) str. YE56/03|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEIYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A2B2RQD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FILLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8E1QT09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A2C1E0S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANIAPVIAKETVPWPKVVH
TQEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGMRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A669EMQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oreochromis niloticus|TrEMBL
MVNQVQRGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQSKEKITGYLAKAKHLGLKNIMALRGDPVGEDWEEEEDGFNYAID
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNY
GIQQAVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELQNEESVFEVFTSYITAQPNHCGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVNGRNLTNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWGK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPELHSEETV
>A0A2B9BPN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYAAAGADIIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPFHMTEAFKMISIPQDGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIAGMKRAIANIAPVIAKETIPRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQQLIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>B7KV73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum extorquens (strain CM4 / NCIMB 13688)|TrEMBL
MPNASQHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVDATKEEIDGVVQSYWDAGVRHIVALRGDPAEGVG
HSYRPHPGGYAQTCDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIEALKAKVDAGADQ
AITQFFFDNEIYLRYRDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLENDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
PAVKPEAKAA
>A0A6G3VW91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID9944|TrEMBL
MALGTASTRTDRARTVRDMLATGKSTFSFEFWAPKTEKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVTAAGCETPVIPEVMPVTSVKMLERLPQLSNAVI
PDALKERILAAKDDPTAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A7X2ZF00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus validus|TrEMBL
MKPDLREALRRGVLVGDGAMGTYLYQMGFPVGISYEELNLLKPDVIRDVHRRYYEAGARL
IETNTFSANREKLSKFGLEGEVEAINRAGVKLARQAVGDDAYVVGAVGSIRAGKRKNVRT
AKVKEDLRQQIEVLADAGVDGLLLETFFDLEEMMLALKLIRKVSSLPVICQFTTEGVGAT
MDGVPMPEAFSKLLAAGADVVGFNCRSGPNGLLRSLEQASGMDEKPPFSVFPNAGLADYV
DGRYTFAATPSYFGESARKFADLGARIVGGCCGTTPEHIAAIAAALEGYMPNESGAQQTR
GISGEAGVFATSEWQKVRGIAITEPPPAEPTIVDLVKERPTVIVELDPPRDLDIAKFMQG
AAALKEVGVDALTMADNSLAVTRMSNLALGSIVQERVGIRPLIHIACRDRNMIGTQSHMM
GLHALGIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGVAFSGKPLKKKAN
FIVGAAFNPNVKYLDKAVQRLERKIEAGADYIMTQPVYNAELIESIYQATRHLNIPIFLG
IMPLASGGNAEYLHNEVPGIQLSDDVRRRMNGLKGEEGRAMGVQIAKELLDVAISRFNGI
YLMTPFMAYEMTVELTQYVWEKAGRRDFHLSPLAK
>A0A7W9JQT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola|TrEMBL
MRARSAGPAAMTQLSFEFYPPKTDDQRAQLDRTAAKLKGCAPEYVSCTFGAGGSTLSYTS
ETVRHLKQKHGFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDL
RYASDLIAFIRAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYN
ADAYFHFRDTVQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDAD
AVRAFGAEVVASLCERLIAGDAPALHFYTLNLAKPTTQVLQLLGR
>A0A838MC74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiaceae bacterium|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYERASVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLSTPPHVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PLASAKTAKWIRSNVPGIHIPDSVIKRLEGAEDQKKEGKQLCIDIINEVKEIEGISGMHV
MAYRQEEYVAEIVHESGVLKGRKPWTREANPADAMVADRLESIRGHKVEDQQQLAGLAAQ
HQPKNPH
>A0A522SM99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiaceae bacterium|TrEMBL
MSQFRFSRRPDIGDKIRASFEFFPPKNVEMEAKLWETVQRLEPLDPAFVSVTYGAGGSTR
ERTARTVGRILAETALRPAAHLTCIDATREEVDAVVREFQAMGVTNFVALRGDPALGVGS
IYRPHPGGYANAAELVAGLGRIGAFDISVSAYPEKHPES
>A0A3N8D593|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Bp9012|TrEMBL
MKSIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAATATRTICERLAM
>A0A2S8SV47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Abditibacterium utsteinense|TrEMBL
MRIDELFSSALPTLSFEFFPPRGEEGETALLNTIEELRPLRPSFISVTRTGGGAPPTIDL
TARIQNELGFRSMSHLTCAGYTQEQIGELLDKAWNGGVRNILALRGDAAPGEQTFSVTEG
GFSAASDLVKFTRERHDFCIGVAGYPEGHPTALNLERDAKYFKLKVDNGAHFGVSQLFFD
NADFYRWRDRIQGMGVDVPLVAGIMPILNVAQIKRFVGMCGAKIPESLLVQLESLESDPA
SVHAAGVEYAIRQCEDLLANGVSGLHFYTLNRSKATFLISQALGMKHPS
>A0A518E0Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lignipirellula cremea|TrEMBL
MRTQLAACYQPGRLGLSFELFPPRTAKGDESLFEHVADLMQFSPDFLTCTYGAGGSTRNK
TLEIVEQVKDRFKAPVASHLTVVGGSIEELRDYLQEAGDRGVDYIVALRGDPPKGETEFR
QAPGGLRYANELVDLIRSEYDHFGVAVAGYPEVHQEAESAEVDLLNLKRKVESGADVVIT
QLFYDNADFWRFREQYQQAGITVPLVPGILPVTNLAQIQRITALCGAQLPESFVARLNEH
PTDDDWQFQVGVEFAVQQVQELIDGGAPGIHFYVLNKSQATSAVLQTVRRTAM
>A0A1U7N4G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena bouillonii PNG|TrEMBL
MTNPTKNSFRTAVESGEFLITAEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQQGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFER
KLEAGAQFFQSQLICDFDRLEKFMDQIAAGTDKPILAGIFLIKSAKNAKFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSAINDLVCK
>A0A3A6RDV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. LS-2|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARTLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
KEVNIPAAPHLSCVGDSKADLRGLLTQYKDAGITRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLKNFVRKANAGADSAITQYFFNADSYFH
FVERVQKMGVGIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>J2SMQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM48|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWKNLKLPR
>A0A1L9WH51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus aculeatus (strain ATCC 16872 / CBS 172.66 / WB 5094)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDKALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKHHGDYFCIGVAAYPEGHPADNFQDSQDPARDVPYL
VEKTQAGADFIMTQLTYDIDAYTKFENMLRNHESGAFKTIPIIPGLMPLHSYKILTRVTK
LSHVKIPPHILSKLEEIKHDDDAVKRAGVDIVCDLVDGIRSLPTPGLRGFHFYTLNLEKT
VSFLLERCDLIGPYTEYDEPIEDSAAYSAARLETPALALASRRSSVSSMPHNRVIVDKLQ
PSDVSSRESVSHEATALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHIPPAVAHKVWGYPVTRDDISALFRRHVSGELYIVPWSEGGAEEGSG
TTLNAETEIIRPELLQLIDKRGWWTLASQPAINGVRSDDPIFGWGPPGEGFVFQKPFVEF
FCPSADYHTILKPLLERHGHEKLAWFATNVRGDFESSLPSANAEDPDPIDINPANVNAVT
WGVFRGKEIVSPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDATKNDVWLVCV
VGQEFGAGTEVGSKEEEEETKWMWRELAGW
>A0A314XKD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prunus yedoensis var. nudiflora|TrEMBL
MKVIEKIQEALLEEKKVLFSFEFFPPKTEDGVENLLERMERMVAHNPAFCDITWGAGGST
ADLTLDIANKMQNIICVESMMHLTCTNMPVDKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQIQGGFACALDLVTHIRAKYGDYFGVTVAGYPEAHPDAIGTDGLASPKPIKLFYDTD
VFLKFVHDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPAEVTAALEPIKDNEEAV
KSYGIHLGTEMCKKILAHGIRTLHLYTLNMEKSALAILMNLGLIEETKISRPLPWRRPAN
VFRVKEDVRPIFWANRPKSYISRTIGWDLYPHGRWGDSRNPSYGALTDYQFMRPRARDKK
LVEEWVVPLRSVEDIHEKFKKFCLGKLRSSPWSELDGLQPETKIINELLGKINTKGFLTI
NSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDALVEKCKALPSLTYMAVNK
DGRWISNIGQIDVNAVTWGVFPAREIIQPTVVDPASFMVWKDEAFEIWSRGWARLYPEGD
SSRKLLEEVQNSYFLVSLVDNDYIQGDVFAVFADF
>Q1I3W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas entomophila (strain L48)|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGNHFHLEVAAYPEMHPQARNFEVDLANFAHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYNKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0Q4N6A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia sp. Leaf53|TrEMBL
MSFFHANQREALNQNLAEINGQINVSFEFFPPRTTEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRAIASDYWSNGIRHIVALRGD
LPPGAGKPEMYGADLVSLLKEVGDFDISVAAYPEVHPEARSAQADLINLRRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQLQRFAAMTNVRVPGWMTQMFE
GLDNDPETRKMVGANVAMDMVRILSREGVKDFHFYTLNRAELSYAICHTLGVRPNTAVAA
S
>A0A7V7MVG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MEAWRGAQRTRLGVIPKDPNPPVENNYIGKSSWLRVVRQEPWPEPLLTNAPHTSTSSAVS
RLEKLLREGLFVVTSECAPPDSADPDAVLNHVQYYEGCIDALNVTDAPGAHCHMSSMGVS
LLLEKAGWEPVMQMTCRDRNRIAIQGDLLSASALGIRNLLCLTGDGIENGDDPGAKPVFD
LDAVSLLDTARRMRDDGVYRSGRELATPPKIFLGAVDNPFVPPFDLRPMRLAKKIEAGAQ
FVQTQYCYDIEVLKRYMECIREEGLHNRCFILVGVGPLVSPRTARWMRANVPGVYIPDEI
IARLEKAQDSKKEGIKICIETIQEIHEIEGISGIHLMAPKREHLIQEIVHASGVLTGRPS
TLVSTGEFTCPSQG
>A0A4Q6FXG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
LLSFETFGDISELQQAIHAAKDVAPELAILAEITVGTDGNMPFGTPAEWAIHKIIEWGAD
VVGFNCSVGPQPLLTLIQKTISSVSVPFIVQPNAGMPKEVDGRTLYMCTPEYMATFTKHF
LQAGVLYVGGCCGTSPEHIRAMSQSFRHQRAMRSAEEMTLQHRIEVLKDETSKTSVTVET
CTPVPLAEKSAWSRKIANGEVVTSVELLPPASVVPTKILESSRRLKEAGVDAVNIPDGPR
ASARMSAILTAVMIEQQAEIETVLHYTCRDRNLLGMQSDMLGAHAIGLRNVLLVTGDPPK
MGSYPNATGVFDIDAIGLTNMVTRLNSGIDLGSRPIGEPTALSVGVGVNPVHADFEYEMK
RFMYKVEAGAEWAITQPVFDLAALYRFMEYIDKNNIKIPIVAGIWPLMSYRNAQFMHNEV
PGVSIPDDIMKRMHDAQTAEDARKVGVDIARGMVASLGRDVQGFQVSAPFGRVELALEVL
SGVTR
>A0A0B3RZN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mameliella alba|TrEMBL
MTGTYPDPTACVSFELFPPKTDAGETALARAVDQMASADPAYFSVTYGAGGSTRDRTARV
VDMVGGRTGRPVAHHLTCVGASRDEVDRLARGLHDKGITRIVALRGDLPEGQSLAPDGYG
DAAELVAGLRRVADFDISVAAYPEVHPEAANAEADLDHLKRKLDAGAARAITQYTFDTEI
ILRFVDRARAAGITAPIVPGIMPVANFAGLKRFSAMCGASVPDWLAQMFDGLDDDPATRA
MIATSVATEQCRLLMEAGLTEFHFYTLNRPEISLAVCRALGLTTGPAAESAA
>A0A1Q8BIQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenarchaeota archaeon 13_1_20CM_2_51_8|TrEMBL
ANSHRIVTVELIPNRVIPAHLPILQGRVDAITIPALRNGENDLSYPAGFRVTPQTRSLAS
AVIVRKTGAEAVPSLTCRDFRRSDLALVPSLFKKGLDNFLVVFGDPYPGNRIEDYDFKKT
EDLIRGVLSVFDGQRPCIGAVTNQYAEDQERETSRTLRKVDAGADYVVTNTAFDDHHVLD
HVDRLRSQGLKAPIFVQVSIPSGLKNLLFVSQKFGIPVPEKVRQTISRNSFGGGIRIAAE
AYAALRTEVNGIHFSYLHRSHNPIPAYTHLLDAIETDGQLTVSIQAALRH
>A0A7Z9M3P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
AADWIHSKTKIPAIFTISTRDMNKSAMQSLLLGAELMGLSNVLIVKGDKFSAEDLNLQSE
VNDFTPTELVSAVKAMNERRDFRGNELTYPTRFCIGAALDLSRDWEKESHLTKSKITRGC
NFIVSQPTFDPELPSKFLSFYEKTIGEKLKIPVIWGIQMVEKDTISFANVPRWVHQNLEE
GGSSYEITIDLVKRYLELGIDTFYLVPTIYKGGRRDYLSAQAVIEDIE
>A0A7V1W108|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSRPWSPSQPERSLDLGALLRTRVVVCDGAVGTMLHAAGASLDLPLPELSVSRPELVRAI
HGAYIEAGADIIETNTFGATRTRLARHGLGERVREINLAGVAVAREAVMAASRRVLVAGS
VGPATPPGSRRRLSPVILREAFREQIAALAEGGVDLLILETFGSLEELLEAIASAEEVAP
NLPIVAQMTFLDDGRTLAGETPAEVAARLDGLDLVAIGANCTLGPQGLLEVLREMGHHTA
LPLSAQPNAGPPTFVDGRFRYTADPAYFARHARRFVELGAAIVGGCCGTTPAHIEAVAGA
VRGMQPVPRHPIPSATPRTRSHGAEKPYSPPSRLLERLAARRFVKVGEIAPPAGGAAEQV
VQEAALLKAAGCDAVLIGPPSSVRAQVSPASLAVLVQQQVEGLEAILTVTTWEKSVMALQ
ADLLGAHAFGVRHVLCRTGTPPLVGDYPNAGGIWDVDSLGLIQLLRGLNEGRDHHGVALA
RPTGFVIGARINPSAEDPEREIADARRKIEAGVDFLITPPVYDLDAFDRLLDAIGVPEDL
PILLGVMILKDFRHAEYLQHEVPGMSIPEPILERMWLAREDGAEVGRAIARELICRARAQ
GRIRGVVLSSAVGSAEGVARLLRELPP
>A0A7C3AWP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MNPEPVSRLEQILKQGEFAVTAECGPPRGANADVIREKGELLKGFVDAVNVTDNQTAIVR
MSSIAACVHLEQMGLEPVMQMVTRDRNRIALQSDILGAYSLGIRNILCLSGDHQTFGSQP
EAMNVFDIDSMNLLHMVRTMGSEGTDMSGFELDEAPHMFIGAVANPFADPFEYRVIRLAK
KIEAGAEFIQTQCVYNTERFKEWLRMAREQGLTEQVHILAGITPLKSANATRYMATKVAG
MDIPDDIIKRIAGVPKSQAAAEGIKLCLETIQELRELEGIHGIHIMAIESEDKVGEIVEE
AGLLPRPVVEV
>A0A831PJM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geoalkalibacter subterraneus|TrEMBL
MSNYPSRSRRFLELCAERIVIGDGAMGTLLYERGVSLDANFEHLNLVRSTLVASVHEAYV
AAGADLLETNTFGANRTRLGAIGLQGRVAEINRAGAWLAREAAGSDRYVAGSVGPLIGPR
GGDAPLEESEKRQILREQMNALAEGGVDLFLLETFSSLADLRLALAVAGEIGLPAVAQLA
FLEGGRTRDGVDAETAVPVLESAGADLIGANCGSGPRDLLAAVKAMAGLTDRPLSAFANS
GFPQYHDGRYIYLATPEYFASMGREMVAAGATLVGGCCGTTPEHIRALSEAVRGSVPAPR
MLPRRTQAASPVEPSCPPCRPTGFLDGWGQRPVVTVEIDPPRGLDCDKVLAAARSLHEAG
VDAISLAENPLARIRLGNLALASRLQQEVGVPVIAHVTCRDRNLIGLHSDLMGAHLLGLR
NILAVTGDPVSLGGESGATSVFDLNSIGLLELLSALNRGTNLMGADLGGHAEFLLGAAFN
PNVRSMEGQILRLEKKIAAGACFVQTQPVYDAALLDEMLRLTKPLEIPVLVGILPLVSER
NAEFLHNEVPGIRLPEAVRQRMRGKSGPEGVAEGLAVARELIDAGRGQVGGWYLMPPFGK
VDIALELIRFIRRSS
>A0A7X3VW12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MFRRLFKEAPLETFSDTLSSGEFVVTTELNPPKGTDLGPLMRRAESLSGMVRAFNVTDSA
GANMTMAPIAAAHLMIDRGIEPILQVTGRDRNRIALEGEVLAAAALGIRNVLCMSGDPPG
RGDHPDAKGVFDLKAETLLEAVTAMNSGKDMYGNELKGTPALFAGAVANPGADDVDTELA
RMEDKVRCGASFFQTQAVYDAASFEKFMEGARGFGVPVLAGMIVLKSGGMARFLNDKLPG
VSVPQSIVDEMDGAKDRAAAGVRITARLIDEVRGMCDGTHIMAIGWESRIPAILEAAGLA
DAA
>A0A3M0IGH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces shenzhenensis|TrEMBL
MALGTASTRTDRARTVRDILRAGKTTYSFEFYAPKTPKGERSLWNALRRVEAVAPDFVSV
TYGAGGSTRATTVKETQQIVVDTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPQGLTYAAELVALIKESGDFCVGVAAFPEMHPRSRDWDTDVAHFVD
KCRAGADYAITQMFFEPESYLRLRDRVAAAGCETPVIPEILPVTSLRMLERLPQLSNARF
PEALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTAPLEIYENLG
LHHPPRA
>A0A2U8FXH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquabacterium olei|TrEMBL
MTTLTRSQPALPISMEFFPPKTPEGVDKLAAVRQQLYPLKPTYCSVTYGAGGSTQDGTLQ
TVCAILREGFDAAPHFSCIGASKDGVRAQLQQFKAEGIRRIVALRGDLPSGYGGFGEFRY
ASDLVAFIRAETGDHFHIEVAAYPEMHPQARNPQADLNAYVTKVKAGANAALTQYFYNSD
AYFRFVDEAAALGADIPVIPGIMPITNSSQLLRFSDACGAEIPRWIRSRLEGFGDDKASI
QAFGLDVVTDLCDQLRCAGVPGLHFYTMNQAGPVKAICERLGLTPSA
>A0A2H1JZD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. 239c|TrEMBL
MSQEVLSTLLKSARYEILPTAGVVDRVHEYVAPGRVITVTASTGLTLEATLSTAEQLQAL
GFNAVPHIAARMVQGRTELEEIVDRITQAGIDRIFVPAGDATPPAGGYAGALDLIVDLAS
MAAPIQHLGVSAYPETHPLIPDDVTIQAMWDKRDYATHLVSNLCFDPGVIATWLARVRAR
GIELPLILGIAGKVELTKLTRVASKIGVGESTRFLRKNTATFSRMAKPGGYNPRKFLDKL
APILDDPTMGVAGLHIYTFNQIKDTEIWRRKQLAALGHTDEVPSTS
>A0A351QRV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp|TrEMBL
MHIKELFKEKEVVFSFEIFPPKPTSSIETVYDTLEGLQGLNPDYISITYGAGGSVNNNRT
CELSSLVKNKYGIEALAHLTCIGSTKSEINEILENLNENGIENILALRGDVPEGNPSIGE
FNNSQELINHIKETKEFGIAAACYPEGHIESRDIEREIEILKLKENAGAEYLISQLFFDN
KYFYKFLNSVEKSNIEIPIQAGIMPVTNRKQVERIVSLCGANLPSKFIKIINRYEHDKDA
LRDAGIAYALEQIVDLVSTGVRGIHLYTMNNPYIAKRITSSIGSILNSINKRQVI
>A0A1F7RX51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Schekmanbacteria bacterium RBG_16_38_11|TrEMBL
MGIKNLCITSETIFDRKVKTEVSNPTEVTALQLIHLIHRLRKGKDFSNKKIKEKPNFTIG
TFLDLSKNDIESYHETIRQKIKAGIEFIITTPLHSPSQIENLTKNIEESGVKIIAGILPT
LSVEAAREVNRTNHKKPIAIETIERLEKAKNPEFEGIHIAAELIKQIKNKVSGIHLIASK
KFIPKISKLSNTNYTPSMTILKEEKDIQKLSHIFEGKLSLKDLEKAYIIRVLKNNRGNRC
TTAEVLGIHRNTLMRKCQEYNINT
>A0A521KIX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MPPMAKIADLLAQGRTLSFEFSAPRDPEGEQRLMRTLGRLAALKPAFMSVTYGAGGSSRG
PTPEVVRHILGLGVTGMPHLTCVSHTREEIRGLLDAYAEMGVQNLLALHGDLPEGTTEMP
AGHFTRAVDLVALARLRTDWSIGVAAHPEGHPKASSPADDIEHHAQKLAAADFAITQFFF
RAEYYERFVATMVARGVRTPVIAGIMPPTNIEGIGRMAALNGTEYPREILARLEAAGDDV
DARREIATEEATRLGEQLLAAGTPGLHIYTMNFSEPARTIARNLGLA
>A0A6C0Q097|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S4.7|TrEMBL
MRDLLATGKLSYSFEFWAPKTEKGERNLWNALRRVEAVAPNFVSVTYGAGGSTRAGTVKA
TQQIASDTTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVRGDPPGDPMGEWVKHP
EGVTYAADLVRLIKESGDFCVGVAAFPEMHPRSPDWESDIRHFVAKCRAGADYAITQMFF
DPEDYLRLRDKVAAAGCDTPIIPEIMPVTNVRQIERFSQLSNASLPPALKERILSAAEDP
AAVRSIGIEYATEFCATLRAEGVPGLHFITLNNSTATLEIYENLGRHEQS
>A0A2W4M5R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSRLADKLRAGEFVVTTELTPPKGTDLSELFAKADALKHLVDGINLTDSPRARMTVEPKS
VGRLLIERGVEPIVQITARDRNRIAIQADMLGAALLGVRNLVFMTGDHPQNGDHPEAKPV
FEMTASDMLRAACALREGRDLAGNALKGAPDLFVGATANPGSSDFDGEVVNTRRKIAAGA
QFLQTQALYESAALERFVAALEPERIALLVGIIPLKSARMARWLNANVPGIKVPEAFIEE
LDAVAGDSEAEVRTGIDIAARIIREVRPRAAGVHLMTMGWEEHIPAILAASGLR
>A0A443HUV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Byssochlamys spectabilis|TrEMBL
MHIKDKLAEEKASGRPGISFEFFPPKTAQGVQNLYDRMDRMHSWGPAFIDITWGAGGRLS
DLTCEMVNVAQSIYGLETCMHLTCTDMPREKIDAALQAAYRAGCTNILALRGDPPREKET
WEAADGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGCDDNRDVDLLIDHLKEKVDAGSSF
IITQMFYDVDHFLNWVEKCRAKGITVPIIPGIMPIQTYAAFIRRSNWTKSRIPPEWLEAL
EPVKNDDAAVREIGTKLVADMCRKLVASGIYHLHFYTMNLAQATRMILEELKLTPSEETP
LHKPLPWRQSLGLRRRGEDVRPIFWRNRNSSYVVRTQEWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSLKDVSETFIRYIEGNLDRLPWSEAPITAEADVIKSDLID
LNRRGFLTINSQPAVNGAKSSHPIYGWGPKNGYVYQKAYLELLVPPGLIDEVIERIEKNE
DLTYYCISKRGELRSNTSDSPNAVTWGIFASKEVIQPTIVETISFLAWKDEAYRLGEDWA
KCHQPSSPSRKLIQSIMDNWYIVNIVNNDFHKTHDIFDIFNGLSVKDIETEVPPSDDIPA
DAQADGAKAEEPKASN
>A0A352NVZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp|TrEMBL
MSLLKEAFEKGNFAVTAEMAPPKGTDLSHLIECANKVKGRVHAVNVTDFQSATLKATSLA
TCKILKDEGLEPVLQITGRDRNRIAIQGELLSAGIFGIENVLALTGDYTGVGDHPGAKPV
YDLDSVGILQVASTLAAGKDMSGNGLSGIPKFYLGACVTPKYEPLELQIIKMRKKIKAGA
KFFQTQAVYDIDTLKEFKEKTKDLDAKIMIGIVPLKSAGMARYMNKNVPGIFVPDELIDR
IKNAEDKTKEGIKIAGEFIRMIKEERLFDGVHIMAIGAEENVPLILDEAGL
>A0A072N5J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudocatenulatum IPLA36007|TrEMBL
MHSPMFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVS
EYGIPSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFEHASDLAV
YIRQQRPDMKIYGACYPEKHPQSATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KARAAGIDVPIEAGIMPVMNAKSVLNMSNKCQSKVPEKLGIMLDKWGGDKALLKEAGIAY
ASEQICELVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A4U1B884|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassotalea mangrovi|TrEMBL
MNYRSARQLDSLNRTVSELSADLQVSFEFFPPNSPEMETTLWNSIERLAPLSPKFVSVTY
GAGSGTRDRTHGVIKRIQKDTGLVAAPHLTCIDASPDELKQIAKDYWQSGVRHIVALRGD
LPESNQKPEMYAADLVSLLKGVQDFEISVAAYPETHPEAPNAQFDLLNLKRKVEAGANRA
ITQFFFDIDAYLRYRDRCVSVGIDVEIVPGILPVSNFNTLKRFAGLTNVHVPNWMYNMYQ
GLEDDPTTRNLVGASIAIDMVKILRSEGVENFHFYTLNRSELTYAICHTLGIRP
>A0A6N9K6L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. BIOML-A2|TrEMBL
MKIRDLITQDKATLSFEVFPPKKDTDFADVEAAALGIAAFKPDYMSVTYGAGGSTKGHTI
QLAREIQEKYDVPTIAHLTCVCASKEGIKTALADMKNAGIENILALRGDIPKNYDGQVFA
EFSHASELVELIKETGDFCVGGACYPEVHPDSANKHEDIIGLKKKVDAGCDYLTTQMFFD
NNIFFNFMYRIREVGISVPIIPGIMPITRRVQVKNAVKLSGCNVPERFKSIVDAFGDTEA
AMRQAGIAYATDQIIDLMANGVKHIHVYSMNKPEVAAGIQKNLSEILKI
>A0A6G9NC90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp|TrEMBL
MTPTLDQLHEHRTAVETPLFSGLPGDIDVSFEFFPPKTEKMEAQLWDAVQQLKVLGPQFV
SVTYGAGGSTRERTHATVSRIIKEAHLPAAAHLTCVGASKAEIREVAEQYWEAGVRHIVA
LRGDAGEPGAPFTPHPEGYAGAAELVKGLKEIADFDISVAAYPETHPDADCPQSCIDHLK
RKLDAGASRAITQFFFSAETFFRYRDALAASGIDKLVIPGILPVTNVAQARKFAGACGAI
IPDWMDGLFEGLDEKPAARQLVAATVAAELCRRLYAGGVRNFHFYTLNRPDLAYAICHML
GKRPVAEAAAVKQGEAA
>A0A8E0RBI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus sp|TrEMBL
MKITDIYREKNLQKKSVISLEVFPPKTDAGIETIYQTVAGLTHKPDYISVTYGAMGSLGR
ENKTLEIAEKIKKEYGIETMHHLTSINNNPEQITEILAEIKAKNVQNILALRGDLPKNTD
VTGCPDIYHYAHELITDIKKTGDFDIAAAIYPEGHVDSPLDVENIEHVKRKYDAGANFFI
SQLFFDNDKFLRLNDYVKNSGIEAPIAAGIMPVLQTSQLDRMLFFGASLPTRLIKIVNKY
KDSPEDLQKAGMDYACKQIDDLLARGVDGVHIYTMNKPFVANTMMDRYL
>A0A4R1ASE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium sp. IC_218|TrEMBL
MSEPVPSLVRLLRAPEPTFSFEFFPPKDDEGEALLWRTIAELEPLGPSFVSVTYGAGGAG
QSRTIRVTRRIAEETSLTPVGHLTVVGQSRGEIEDVLKQYAASGVRHVLALRGDPQGGPR
APWETHPDGMTHATELVELARDLGGFEIGVAAFPEGHPDCETLERDAEVLAAKHAAGASF
AITQLFFRAADYFQLVDRLHANGSDLPVVPGIMPVLNLNQVARMAELSGVAIPDEVLAEL
EPHRDDPAALRAAGIDLAVRLCRELLDGGAPGLHFYTLNRSKATREIFEQLRPLA
>Q3J4G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.)|TrEMBL
MARPRISFEFFPPQTLEASFRLWETAQMLAPLKPDFVSVTYGAGGTTRKLTHDAVETIHT
HYKLNVAAHLTCVDATKAETLEIAASYAEAGVTEIVALRGDAPKGVDRFTPHPEGFASSV
ELVEALAATGRFKLRVGAYPEPHPDAADTLADVRWLKRKIEAGATSAITQFFFEAETFLR
FRDLCAKEGITAPIIPGILPIENWSGVKKFAARCGAQVPGWLDDAFDHARRDGREELFSV
ALCTELCDRLLSEGVEDLHFYTLNRPTLTREVCHALGILPEVALQNVA
>A0A5X6EJB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Aqua|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A086TL80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Podila verticillata NRRL 6337|TrEMBL
MKIVDKIAEKAAEKNPFYSFEYFPPKTSQGLSNLYDRIGRMQSLSPTFVTCTWGAGGSTF
EKTTELSAVAQTVHGLETCMHLTCTNMDRGKVDDALAEAKRAGIQNILALRGDPPRGQEY
WTQVDDTFVHAIDLVRYIRQQYGDYFCIGVAGYPEGHMDSTETDSSVEIQYLKEKIDAGA
DFVLTQLFYDVDGFLAWEKQCRSQGILCPIIPGIMPIQSFNGFRRITKLAKIRVPTTVAE
SLEPIKNDDQKVKDYGVTLAADTIQRLLDAGITGFHICTLNLEKSVRLILERVGFVNPAT
TRRQQQHHQIINEPVHKDGRRDSVDGTLNPVIWNPTDDHLGRSESWDDFPNGRWGDARSP
AFGDLDGYGASLKVKPWKALELWGRPKNVEDISQLFVKFIQGTIPLLPWSEGAPLPETEA
IQARLVTCNQRGFLTVGSQPAVDGKPSTDPLVGWGPKGGYVYQKAFIELFVGPNEVVALV
EKLRTSSPWITFLAASRDGDVVTNLTGDVLEEQNKIAELKKICGKKQDKVKKDAVASPSS
SSSSSSTTTEEAPACETFSNKLEDELVEDSNAVTWGVFPGKEIIQPTVIEKVSFLAWRDE
AFEIWREWEHLYPKGSESRKLLHQIGHDYWLFNIVNNDFRDPDGLWDIVA
>I3TIS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tistrella mobilis (strain KA081020-065)|TrEMBL
MMTVTTDGRVLTPRALWDAPAPVPGLKISLEFFPPRGAQAEARLWETVARLAAYAPDFVS
VTYGAGGSTRDKTRDTVLRMRRDYGLAAAAHLTCVDASRADVMAVAEGYIADGIDHVVAL
RGDPPQGAGPYVPHPDGFPFAVDLVRALADLGRFEISVAAYPEVHPQAQSAGADLDNLKA
KLDAGATRAITQYFFDPAVFLRFRDRAAAAGITRPILPGLMPVLGFQQIKRFSAACGAGI
PDWMERLYDGADADEATHQAVSAMLLAEQARVLAAEGCADLHFYTLNKAELTISACHLLG
IRPRAEVAAARAAG
>A0A543AN38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enteractinococcus coprophilus|TrEMBL
MSQPTNTENVRALVQDASLEMTGKDVEALREAAPFIAPGTRINVTFLGNEDLEMRVTASK
AVKELGFIPVPHISARRLRSEDELKEFLQALADVDATECVFAVGGDPAEPMGPYGSSLEM
IESGIFADFGVKEVSIAGYPEGHPDISNEVLTRELNGKLDELAKQNLGARILTQFGFDTD
PIATWLNEVAADNVTAPIGIGVPGPAGIKRLLTYARRFGATTSAGIVKKYGFSLTNLMGS
AGPDKFIGNLADVVAASDYQGEVGVHFYTFGGMTRTAEWLQDFKNKL
>V2HNZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp. HPC(L)|TrEMBL
MQDRYYSFEFFPPKTPEGREKLRNTRAQLAPLGPKYISVTFGAGGTTQQGTLDAVLEIQR
DGIDAAPHLSCVGSTREGIREILRTYRDNGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFQIEVAAYPEYHPQARSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRALGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDREAIRAFGLDV
VTALCERLLAGGVPGLHFYTLNAAGATKAIWQRLKL
>A0A8E5U0N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella sp. SJTUF15034|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1R3GLX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corchorus olitorius|TrEMBL
MKVIDKIKSLQGGEGENGKVVFSFEFFPPKTEDAVDNLFERMDRMVAHNPSFCDITWGAG
GSTADLTLDIANKMQNIICVETIMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPH
G
>A0A438GY59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vitis vinifera|TrEMBL
MLMGDLCQLAKDMAQNLLASDLFNELDPEGYCCLEPIKDNDEAVKAYGIHLGTEMCKKIL
AHGIKTVHLYTLNMEKSALAILMALPMETPDNVFRVKEDVRPIFWANRPRSYISRTIGWT
NIHMDDGVILVSIIWRINRLSAMEALSCFMLKVVGGYSQGIKGFWLGSWLWRFAVDGVGL
WMKVIVGKVGKGHGVGSLENY
>D8JJQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter oleivorans (strain JCM 16667 / KCTC 23045 / DR1)|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFESFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLMKHAYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
TGKEFSPEISRFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENSLVAK
VLIKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKEKLIPTVPIETRGTSSWKNWYLVTEA
>A0A367B3Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. TF02-8|TrEMBL
MTPTVRELLATERPTWSFEFFPAKTPEGEVQLWQALRELERLQPSFVSVTYGAGGSTREG
TLAVTERIATETTMTPLAHLTAVDHSVAELRHIVSRLAAAGVRNVLALRGDPPGADPQAE
WIAHPEGLQYAAELVELIRSIGDFSVGVAAFPEQHPRSPDPDSDVEQFVAKCRAGADFAI
TQMFFRAEDYLRLRDRVAARGCEVPILAGVMPVTNVRQITRIVELSGQAFPADLVERFAA
LDGDRSEDKAAVRDLGVEVATDLCRTLLDEGVPGIHFITMNRSTATREVFTNLVGGGPSV
TP
>A0A1V5I8T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistetes bacterium ADurb.BinA166|TrEMBL
MHIHEILRQRRPSISFEIFPPKPEYPIETIYTTIAELKPLAPDFISVTYGAGGSSRERTV
EIASAAQNRWGLVSLAHLTCMGSTPAEVEGILEELEQEGVRNVLAMRGDPRPEGGASHFL
HASDLIRHIRRGHFSDFSLGAASYPEGHPECPSLEEDLVHLKEKVDAGADFLVTQLFFDN
EIFFRFVDTVRAAGIEVPVLAGVMPVLNSRQIGRIVSLCGASIPPRFARIMSRYEHSPDA
LAEAGMAYATEQIIDLLSWGADGVHLYTMNRPDVARRIMEGLSTVRRALNGSEGV
>A0A1Y2FFJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Protomyces lactucae-debilis|TrEMBL
MRISKKLKRNEEDNAPPSYSYEFFPPKTSTGMQNLYDRIERMANWGPPLFVDVTWGAGGR
LAELTTEMVSTTQELFGLDTCMHLICTGMPAEKVKEALKDAYDAGCQNILALRGDPPRDK
EKWEKTEGGFAYATDLVKYIRKEYGDYFDIGVAGYSEGHPECTDKEMGLHHLKEKCDAGA
DFIVTQMFYDVDAFLAWVQRCRDMGITVPIIPGVMPISGWDSFLRRAKWSNAHIPQHFMD
ELEPVKNDDAAVRDRGTKLVAEMCQTMLDNGIRHLHFYTMNLEKATHMIIERLGLLKDVK
PREMPWQRSLGLNRKDESVRPIFWANRHKSYIARTKEWDEFPNGRWGDSRSPAFGELENY
QIGLRVPASQVPELWGTPASVQDVADLFARYCLGEVPSLPWSESALAPEASIIQQNLASI
NRKGYLTINSQPAVNGAKSSDPLYGWGPANGYVYQKAYLEIFVHPDLLPQFIKRVEQDRA
NTYFAVNKQGDLKTNTNSDGPNAVTWGVFPGKEIIQPTIVEAISFLAWKDEAYRLGLDWA
TSYDADSPARKLLTGIMDTWYLCVLVSNDFQDDNALFTLFEDMRPVSSLSKA
>A0A550F379|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mendocina|TrEMBL
MSQQRRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTVNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGDHFHIEVAAYPEMHPQARNLEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRVFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSQAIWNNLDLKR
>A0A0L6WGH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Termitomyces sp. J132|TrEMBL
MKISQKIEKQQKEGKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPKEKVDIALREAKAHGCRNVLALRGDPPAGQEA
WEAVEGGFIHGIDLVRHIRKNYGDYFDIAVPGFPQFQLLPPAERDLEMKYLKEKIDAGVD
FIFTQMFYDVEIFIDWVKAVRAAGITIPIVPGIAPIQTWNGFMRATSLAKTVIPQFFMDA
LEPHRNDDEKVRAIGTKLVADMCRRILKEDLGILGLHFYTMNLEKATKMLLEELNLVPRV
ETLKPLPWRQSLTPNRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWFKQSKEDAIKLWGYPTSFSDISSLFARFCKKQLAALPWSDQAPSSETAVISSQLA
QMNDLGFLTINSQPAVNGARSDDKVHGWGPSNGYVYQKAYLEFFVNSALLDLLLKYIERD
SNITYYVINSRGDLKTNTHSDGPNAVTWGVFPGKEIVQPTIVEAISFMAWKASYELGQQW
AQIYDEDSPSRKLISDFMETSSLVNVVHNDFQDLEAIFKPFFLAGEEYRALNATSPIVNG
IIEH
>A0A318C4N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pokkaliibacter plantistimulans|TrEMBL
MSKPNFSLEVFPPKTAATTLSLWKASQELAPFKPEFISVTCGAGGNAPGDTTKEVALVMA
QQAHCPVAAHMTCVSGSREELLQLARDYWQSNIRHIVALRGDMPGQERYTPRADGFAYAD
ELVAALKEVADFDISVAGYPEGHPDSSSMDKELEYLKKKADAGANRIITQFFFDPEVFLR
YRDRVAAAGIKAEVVPGLLPVLNFKKMTAFAARCQTSVPEFLHKMFEGVEAEDIDHRLLA
MNILSHQITRLHTEGVNFFHLYTLNESMLTRHVCRWIRSAF
>A0A1W6ZSP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodoplanes sinuspersici|TrEMBL
MNIPVVNLFKTKTAADSEVSATIGHITGFLSGFSVEATRPKPGDVEAVAQNAPGGTHLYL
SAIPTRPSTELVEQAVLTRKAGIEPVPHIAVRNYASKDELSSLLQRLSEEAGVRRILVIS
GDRPDSAGAFTASIEVIESGVLQKYGIEEIGIAGHPDGHPVVADGVMQRALLAKIEAAEQ
GGLKADIVTQFGFDAMAMIRWVKKLRDLGVEAPVRIGMAGPTNLTTLLKYAQRCGVKASV
GGVAKHAGLVKHLFGVSAPDGIVRALADANATGSLGPVSAHFFSFGGIGATTRWASHAQK
GRMTLDSEGFTVEA
>A0A2W7NEX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Breznakibacter xylanolyticus|TrEMBL
MTVAQLINHTKSTAFSFELLPPLKGNSIDRVFNTIDALIEFNPLFINITSHRSEETFVSV
GNGLYERKIERKRPGTVAMAATIMQKYNVKVVPHIICSGFTRTQTQQALIELNNLGIHDI
LVLRGDKGGMDKFYKPAEGGNANAIDLAHQVTDLNAGKFIDGSMGNPLDTPFAFGVAGYP
EKHDEAPNLDADFYWLKKKVEAGAEYIVTQMFFDNQKYFDFVNRCRAEGITIPIIPGLKP
ITFMNQATVLPKIFHVDIPEDFAKEMRKCKTDEAVTRVGIDWCTMQAKDLIKNGVPIVHF
YTLMATQSVREVAKAVY
>A0A1G4RE54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium mongolense subsp. loessense|TrEMBL
MALNTGDRRNIGISFEFFPPKSEEMEGQLWKTVAELQDWDPDFVSVTYGAGGTTKAPTLT
AVTRFLNETPLATASHLTCVGATKEETHQVIDHFRKAGVKHFVALRGDAPGGAGVPYQPH
PGGYANAAELVAGLREIDDFEISVSAYPEKHPESRDVAADIDMLKRKADNGADRALTQFF
FDNDNFERYLEKVRTAGIKIPIVPGIMPIQNLTQLKRFASACGTVIPAFLDERFAGLDDK
VEERAKVAVDVAVEQIEDLVRRGLDEFHLYTMNRSPLVSAVLTNLGLRREGAKRAAGAAA
>A0A251ZTW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Commensalibacter intestini|TrEMBL
MTRISIELIPRDKQSLITDMQNIKEYFPVADTINIPDLMRFPLHSWESFDITYPLYPNTI
PHVRAIDIDPNAPLPGYNQKNLKEVLVIQGDPPADLHKITYPNTTETILRRYQKELPHLT
LYAAFDPYRRSPKEELEHIQSKEAAGAKGFFTQPIFDEKLLEVCMDWLHDKNVFWGLSPV
VGPRSKSYWEVTNNVIFPQQFEPTLEANIAFAKRALNLIKQTNSNTYLMPLRVKLEKYLP
PLLEVFL
>A0A252E3R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. 106C|TrEMBL
MSDTQSTTVLNAFRRAAQAGEFLVTAEVAPPKGGDPTHMLQMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQHGIEPICQIACRDRNRIGLQSDLMGAHALGIRNILALTGDPVKA
GDHPDAKSVFDLEAVRLLQLIRKMNQGFDSNEQSLTDGALDLFTGAAVDPQCASLSGLQS
RFERKIEAGAQFFQSQLITDFERLEKFMDTIAAGYKKPILAGIFLFKSAKNAQFINKCVP
GVNIPQHIIDRLAKAKHPLEEGVKIAAEQVQIARQLCHGVHMMAVKREDLIPEILDLAGV
APVNLVLTK
>A0A1A5D9H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. EGD-AKN5|TrEMBL
MTTSDRRFSFEFFPAKTEAGHEKLLATARQLAGYKPDFFSCTYGAGGSTRDRTLVTVLQL
DGEVNVPTAPHLSCVGDTKAELRALLAHYKDAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRAETGDHFHIEVAAYPEVHPQARNSEHDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAQKLGIDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIASIQSF
GEQVITEMCERLLDGGAPGLHFYTLNQADPSLALWKNLKLPR
>A0A087ACV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium callitrichos DSM 23973|TrEMBL
MHKPMFSLEVFPPKRDAPVGTIYDTLDGLQGLDPDFISVTYGHGTHADRTATARIANTIR
NEYRIPTVAHLTALYSDEAKIDEALDMFEHAGVSAVLALRGDYIDGEEPVGVFEHASDLV
RYIRSRKPDLKVFGACYPEGHIQSESLDEDIEHLKEKVDAGATHLISQLFYDNEDFYRFL
DKARAAGIDVPIEAGIMPINGAKSLRSMAAKNRTRVPKAVESLLDKWGSDVPTLREAGIN
YASAQITDLVAHGVDGVHLYTMNRPATTRRIWRNVRPLFQTAE
>A0A2N0BIL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira ellisii|TrEMBL
MCGRKFLNLVRKIGIGVPVIPGIMPITSFSQIERFRSIAGCEFPSSLIRDLQEVEHRPEE
FYRRSLNFTVKQCRELLDMGVPGIHLYTLNQSHASYDIVRELKDDSV
>A0A7H0T851|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas psychrotolerans|TrEMBL
MKPSLSFEFFPCKTEAGHEKLIATARQLASHGPEFFSCTYGAGGSTRDGTYRTVRQLNDE
VGVPTAPHLSCVGDSKAKLRELLQQYREAGINRIVALRGDLPSGMGLSGGGELRHASDLV
AFIREETGDHFHIEVAAYPETHPQARSFTDDVRNFVYKMQAGADRAVTQYFFNADCYFHF
VERVRKLGVEAPVIPGIMPITNYSKLARFSDACGAELPRWLRKQLEAYGDDTQSIQAFGE
EVMTDLCERLLEGGAPGVHFYTLNQAEPCIAIWRNLGF
>A3DBL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372)|TrEMBL
MNLVDLFKKKKPVISFEIFPPKLDTPIESIFGTLEQFKELKPDFISVTYGAGGSAKDRTI
EIASKIKNEYGIESMAHLTCVGHSKEEIDALLTSMREHNLENILALRGDPPANQPDFDFS
NNAFKYANELIAHVRKQNRNDFCIAAAAYVEGHVNSKRLKDDLLYLKQKVDTGVDFLVTQ
LFFDNRLFYDFLDKTASIGITCPITPGIMPIFKADQIKRITYLCGASIPAKLVIMMDKYG
DNDEDMRKAGIEYASNQIRDLIDNGVDGIHLLTMNRPKSTREILTNIGLLK
>E2X3E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella dysenteriae 1617|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVPAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1V3J966|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter genomosp. 1|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMETMLWESIHRLKVLEPKFVSVTYGA
NSGERDRTHSIVKSIKQETGLEAAPHLTGIDATPEELKQIAKDYWDSGIRHIVALRGDEP
QGYEKKPFYAADLVELLRTVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDNYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPTWLSKAYEGL
DDDPTTRNLVAASVAMDMVKILSSEGVNDFHFYTLNRSELTYAICHMLGVRPRG
>A0A1F6U6F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Muproteobacteria bacterium RIFCSPLOWO2_01_FULL_60_18|TrEMBL
METQKKRPRTFSFEFFPPRNEDGCARLRETVEQLAQLKPKFFSVTFGAGGSTREGTYETV
KNIQAQGQQAAPHISCIGTTRADIRALLDSYRQLGIRHLVALRGDLPKDAPKTGGDFHYA
NELVSFIRAETGDEFYLEVAAYPEFHPESPSPESDIRHFANKVRAGANSAMTQYFFNVDA
YWRFVEECSALGIDVPIVPGIMPITNYKQLAKFSDACGAEIPRWIRRRLEGYGDDLDSIR
AFGLDVT
>Q28TL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jannaschia sp. (strain CCS1)|TrEMBL
MPTPNVSFEFFPPKSLEGSFKLWETLGVLAPLDPTFVSVTYGAGGTTRKLTHEAVTAINA
NFGVPVAAHLTCVDATRAETLEIADQYAQAGITQIVALRGDPPKGTATFQAHPDGFGSSE
DLVAALAKTGKFDIRVGAYPDPHPEAASMQACVDYLKAKIDAGATSAITQFFFEADTFFR
FRDACAAAGITAPILPGILPIEDWSRARRFATACGAVIPTWLDDAYTSAIRDGREDLLST
AICTELCTDLIEGGVDDLHFYTLNRPELTRDVCAALGVAPNVALAEVA
>A0A380NFI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseus|TrEMBL
MALGTASTRTDHAPTVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSEDWDTDIRYFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LQDDKG
>A0A1X2GYQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hesseltinella vesiculosa|TrEMBL
MKIVDKLQLAEQARQISFSFEFFPPKTEQGVVNLFDRLGRMAQWEPTFMSCTWGAGMSTE
ERTMSICSTAQVVHGVETLLHLTCTNMDITHIDEVLKSAKEAGIQNILALRGDAPRGHEY
WTPAENGFHHAIDLVRYIRQQYGDYFCIGVAGYPEGHLDSTSPDDDLHHLKAKIDAGADF
IMTQLFYNVDVFLAWQASCRALGITVPIVPGMMPIPTYQNFRRMINLCNTQVPDTILQEL
DAIKADDQKVKEYGVQLAVQMIQQLLKQGIYNFHISTLNLERSTKRILQQLGRLAPDMTA
TTMPSHLTPLPLVQDLEHAENWDEFPNGRYGDARSPAFGEMTFGAGQRQSTWEASRKWGF
PTTPADITQLFEQYILGRVASLPWSDEALTTETDTIRQTLLDINRRGYWTVGSQPAVNGA
PSHDPAVGWGPRGGYVYQKAFLEFFVSQEQLTSLLAQCHRDPFVTYYAMNQKGEFLSNVQ
DPEAQNAVTWGVFPGKEIVQPTLIERANFEAWKEEAFELWMQWEQQYEPSSPTAQLLRQV
RESCWLVNVVHNDYQRQDALFNLMLS
>Q47R29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermobifida fusca (strain YX)|TrEMBL
MLGSPTPRPAPRPRRISELLARKEPTFSFEFFPPKTPEGERMLWRAIREIEALRPSFVSV
TYGAGGSTRDRTVNVTEKIATNTTLLPVAHITAVNHSVRELRHLIGRFAAAGVCNMLALR
GDPPGDPLGEWVKHPEGLTHAEELVRLIKESGDFCVGVAAFPYKHPRSPDVETDTDFFVR
KCRAGADYAITQMFFEAEDYLRLRDRVAARGCDVPIIPEIMPVTKFSTIARSEQLSGAPF
PRRLAEEFERVADDPEAVRALGIEHATRLCERLLAEGAPGIHFITFNRSTATREVYHRLV
GATQPAAVAALP
>A0A423NYT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas moraviensis|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETADHFHIEVAAYPEMHPQARNYEDDLANFVRKAKAGADSAITQYFFNADSYFY
FVDRLHALGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTRSIQSFG
EQVVSEMCERLLQDGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A2N3I9S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labilibaculum manganireducens|TrEMBL
MKVIELLNQAIENKTTHFSFELLPPLRGNSIYKVFNTIDKLKEFDPKYINITAHRDEVVF
TESESGLIEKKITRKRPGTVAVAAAIKNEYKITVVPHVICSGFTPEETENALLDLNFLGI
YDLLLLRGDSSSRHAFISSEGEHKYAIDLINQVNKINKGGFLDGTHVEPFATPFSFGTAG
YPEKHEEAPNIDSDIYWLKKKVDAGAEYIVTQMFFDNQKFFDFVKKVRDAGITVPVVPGI
KPISALSQLTVLPQIFKTDIPEALAAEVRKCKTNDEVKQVGIEWGIQQGKELIQHGVPSL
HFYTLMASDCVKEIAKAIY
>A0A0K2G846|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira moscoviensis|TrEMBL
MTREPQQRLKDALERGTFAVTIEYNPPKGTNIAPVLDNAKQLVGRVHGVNVTDNTAAVVR
AGSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHK
EAKPVYDLDSVQVMQLVQGLNAGRDMAGNKLDGSTDFLIGAAVTPEADPLGPMLAKFEVK
VKAGAQFFQTQAVYNPDQFAGFMKAVRPFKVKVLAGILVLRNAKMAEFMNANIPGVSVPQ
EMIEELKAAGDKAEEAGVEIAVRTIKAVRPHCDGVHIMAIKATHRLADIIAKAELG
>A0A151GEZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drechmeria coniospora|TrEMBL
MDKITEKIAALPADAEYFSLEFFPPKTAMGFANLRHRLERMEQALRPLFVNVTWGAGGST
STKSLELAELCQRELGLTTCLHLTCTNMSRRLIDKALEDAKVLGIRNILALRGDPPRRDE
YRDADADADSDGLSDEFNWAIDLVRYIRAKYGDYFCIGVAAYPEGHADESHPLGQSFEDD
IPSLLDKVRAGADFIMTQLFFDIEAYAKFETTLRDHLEGAFKDIPIIPGLMPIQSFQMIR
RTTKLSHAKMPEPILERLSAVKGDDEQVKLVGVDVITELIQQIRTIKRSPTCRRGFHFYT
LNLEKAVSFIVERTGLIPPCSESESESDEAVLDESKPPTPRIQVNGDVPPRTSSHSRTSR
RPSVGSDPHNRVIVGDRRPTLPEWETSSLEAAIPAGLFNSRSNTLAISEGEGVLGREATW
DDFPNGRFGDARSPAYGEIDGYGVSLHMSVTQAVRLWGHPKTREDIDAIFVKHINGELEA
IPWSEEELMAESSTIKTELHALNSKGLWTVASQPAVNGLPSNDSTFGWGPPRGFVFQKSF
VEFFIPSADWKALRDRLTRPSVADVVCFYAANASGDFVSSDTTGGVSNATEAGSSTNAVT
WGVFPGKEIMTPTIVEEVSFRAWAEEAFGIWGEWASVYGRGSESEKLLNDLRDDCWLVNV
IHHEFVEKEALWKLLID
>A0A2A5BXX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxellaceae bacterium|TrEMBL
MESQKKYTPRFSFEFFPPKTDVGINKLKQVSETLGQQNPAFFSVTYGAGGSTRDRTFETV
ASVKEITGIATAPHLSCVGDTREQLRELIHQYKDNGINRIVTLRGDLPSGMGASLGELKY
ASDLVAFIREETGDHFHLEVAAYPEMHPQATSMDADLKAFKAKVDAGASSAITQYFYNVD
AYKFFVDSCEKMGIDIPIVVGIMPITNHDKLMRFSNMCGAEVPRWIRTRIESHATDLDYI
TKFGEEVVTNLCEQLLELGAPGFHFYTLNQAEPSLSIWKNLNLSDI
>A0A496QKH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteria bacterium|TrEMBL
MLGAAANPFADPFEYRPIRVAKKVDAGASFIQTQIIYNVAKFTRFMKMVRDLGLHEKVYI
LAGVTPPKSVGMARYMKKFVPGLDVTDDVIERLKGAKDPKEEGINICVDIIKQVREIPGV
AGVHVMAIEWEQAVPEIVSLAGLSPRPGAQAVEPRLRSSEAIELIVSEAKENAKAEIEKA
LEQAKAEAQASRDLVVKEKERVTSEVSGLKRQAQEAKAIAGQKETEIERLNSELAKTKAG
QGHVQAVRGPAGKRESSALSSRERSALTSLRSGLEALSKGLGINEDQLEALRRFFEAEFL
LHPDTAEQVTVPSEEPSAPRKEIEKPRAETRHKEVVNLVAKGNILLHKNDAAKALDAFEK
ALAIEPKDQRAGEGLKKAREVLEIVASAKAAPAVPEGVPPCPEGLSPEEWQSKWMIRLVA
TGNVCLHKGDLGGAQKAFKQALELKPYDEKARAGLLKAESVEAAPVLVPAEPEVPEKTEV
PPTPEPKAAPVTEEIKAEAKKETPAATTPTGIEDLSVAEFPRETMSLSERAGSISGNQFT
ESCTSAIYEVSLGEGEKALTVGGSSTLPFHVFEGDMPHAPQVAFGILDSEPEDWPDVLSK
YYSDVFSDPVAWAGKCINDYGAEAICLSLVSTDPNGMNRPSDEAAKVAQSVIEGIDVPVI
LWGCGNAEKDTETLREVTNLVGNRKVCLGPLSDANYRSLGATAMAFQLPVVASTPIDVNL
AKQLNILLENLGLSLNQILMDPSIGAVGYGIEYSYSVMERIRLAALTQQDEKLQVPFICN
LGREVWKTKECRLPSDALLGDQERRGVLMEAVTASTLLLAGGELMVMMHPKAIALTEALI
RGMM
>A0A6I4PG52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. J1-007|TrEMBL
MGWTGERPGRPAPPSAPPRPPPSPPCPPPAPDRAPPPPPALPPAPVLPSAPAPPPAPAPP
PAPAPAPAPPPAPAPAPALASVLPPVPPPCPAPPPHPAPAPPPALPPAPALPPDRAPVWV
PGRSSEPLYRGSVGLAHATPAPGPGPHHPRSPRVRGRSFSFEFFPPKTDKGARNLWRTIR
ELESLQPTFVSVTYGAGGGTRDKTVDIVERIASDTTLTPVAHFTAVEHSQAELRHLIGRF
ASVGVRNILAVRGDPPGDPMGEWVKHPEGVEYAADLVRMIRSYGDFCVGVAAFPYKHPRS
PDIESDTRHFVAKCRAGADYAITQMFFRAEDYFRLRDRVAAAGCDVPIIPGIMPVTQMST
IERSEQLSGAPFPAEVRARFEAVADDPEAVRRLGVEHAAEVCRELLAQDAPGIHFITFNK
STATREVYDLLDAHAYSYSGGYGAKGSVPPMTA
>A0A7V4AA64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Calescamantes bacterium|TrEMBL
MANFREKIEKGDSFLITCEISPPRGPNTESFEERLKEVRGKVDAVNLTDNPMLSVRMTPV
VASLFAIKNGIEPIMQITCRDRNILGITSDLIGAWAIGVRNVLALWGDMPKEGKPKGVFE
VDTTELIKLITDLGKGLDFRGNEINSRCDFFVGAALNPFDEPEKLKENAEKKISAGARFF
QTQPVFDLNSITHFADFVYKNKINVLLGVIITPSEKTLENIKKFAKGMVIPEELEENLKK
YESKEDKEKVAVEFCSKLIEKIKQTKVFRGVHIYSPTKESLIGKLLEFLPV
>A0A6G8G342|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycicoccus sp. HDW14|TrEMBL
MHPCPAPGGAALDQLRVLPPKDDAAEALLWDAVRRLERVRPAFVSVTYGAGGTSQDRTVR
VTARIADETSLTPLAHLTCVGQSVRDLRQVVGHYAASGVRNVLALRGDPPGDVRAAWAPH
PDGLDHAEDLVRMVRALGDFTVGVAAFPDVHPDSPDLDHDVEVLVRKADAGASFAITQMV
FDADTYLRLRDRVAARRDLPVTPGLMPVTNVRQIQRMSELMGTPLPPGVVQRLEAVKDDP
AAVREVGVQIATELGRRMLDEGAPGLHFITMNRSTATLEVHENLGL
>A0A818V8C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MASYEEDLRYLKEKVDYGADFIITRLFFQPATFIKFESDCRSIGIQCRIIPGIFPIQAYA
SLKNIVRLAKLDVPEEILACIEPIKYNGEAIRNFGVQKCVDLCRTLLDSGKIHGLHFYTL
NREYATIEILRKLDRCVRPKSYVHRTSNCEEFPNGRWGLPFAPSFGVLTDYHLFYIKIDA
TRDALLDEWGHELADKQDVRRMFACYIADEKNGRVKIVHHFPWKDEAISPETNFIHDHLI
KYNRKGILTISSQPAVNGKSSTDSIFGRGIKKWLCLSKSLFRIFTSEKKIPALRAVLKKF
PGVNYHFVNKSGEVNETSTEGEQPIALIWGVFAENMSRTTFLNVDDTKAGMEDLDKEKIN
KLIQDASKNSKFFKQQQRREEDNRRRIEVKLSKIKSFTPFQIEQAEKSVDRYLAQLDKTR
DLSRTFCHIDMDAFYAAVEMRDNPALQHVPMAVGGESMLSTSNYLARQFGVRAAMPGFIA
RHLCPNLVIVRCDFEKYRADSVKVMKIISEYDENYGSCGLDEAFADLTNHLQIRTNFSEQ
QRTFPKEENSTETITFGMTAEEVVQEMRHRIHLATRLTASAGIACNMRLAKLCSDINKPN
GQYQLESNVEVILNFIRNMPIRKIKGIGKVTALHLESLEIQTVNDIYLKRGILKLIEYPT
TFDFLMRVSNGCGSTTIEHDDLQKSVGHETTFNSVRDSSQLISLCRDLAKKTVDELISHC
LLCKRVTLKIKTVNFENLTRSKTLSSYTDSLNVIADKAVALLKHELDQDIELPALRLMGV
RVADLKMKSSDLPILQFFSKKSTTTINENVHDVIEDIDNVDEDEEEEREKDENENEEFLS
MENSHLGGCDSKLTHQDDEDSNSSTTACPVCQKLLLGDNEKINKHIDLCLNGEMVRTTIK
EENRRTSPQTKMNKRIQLTQSKSTPPKKRQKRKSDATPQRAHGIDNYFFKTESK
>A0A829ZAF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] cocleatum|TrEMBL
MKIIDLLHQRPTLSFEIFPPKNHDGDISSIYSTIDELAKLKPDFISVTYGAGGSTTENTV
EIASKIKNDYNIEAVAHLSCIDATPEQLTRIINSLKANNIENILALRGDYPKGYDPVNAP
HYYKYASELNEFISKNYPDTFCLSGACYPEVHQDAVSLEEDLQALKKKVDSGAEYLITQI
FFDNNYYYRLVREARIRGINVPIIAGIMPATNSKSLLNIAKLSGCNIPYNLSAMIERFKN
NPYAMKEVGLNYATYQIIDLITNGVDGIHLYTMNKPEIAKEILLRTNNIFAEFIND
>A0A5K0XD79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nymphaea colorata|TrEMBL
AGAVGLRVFLFPSHWSRNSSLPLNPSLADLFFFFRNNKKVEMKVIEKIREAAKEDRVIFS
FEYFPPKTQDGVDNLFDRMERMVAHNPSFCDITWGAGGSTADLTLDISNRMQNV
>A0A851EZ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pitta sordida|TrEMBL
MVNETQQPCSASSSSRSDGSSSGSEGSKDSSRCSTPVLDGDRHERLREKMRRRQEAGDRW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTTDDITRHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFFKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWNEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6G9GSB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces liangshanensis|TrEMBL
MAAETADRPPYSPSGPRGLLSGWSEGRRSFSFEFFPPKTEAGERTLWNAIRRIEPLAPTF
VSVTYGAGGSSRDRTVEVTKRIAAETTLTPVAHLTAVGHSVAELRHIIGQYADAGIRDVL
ALRGDPPGDPRGEWVRHPEGFAQASELVSLIRDLGDFTVGVAAFPERHPRSADWDTDIRH
FVAKCRAGADYAITQMFFDVDDYLRLRDRLTAAGCTTPIIPEIMPATDVRQIRRFAELSD
ARFPDHLARRLEAARDSPADGHRIGVEHATAMAERLLAEGAPGLHYITLNRSTATLEIHQ
NLGVAAREPRVPAAAPR
>A0A7X1KLW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium flavum|TrEMBL
MIPLNQLFADYSIEATAKDAALLGALGKEPARPAEVFVPWLPEEGDAARIAACVAVRAQG
FEPVPHISARRIESLEALDRLLGALRAEAGATRLFLIAGDLSRPSGPFSDSLSVIETGLI
ERHGFTSVGIAGHPDDHPDVPDEVLWQAMADKLAALKARGLAAQVVTQFSFDAQRVVSWL
AEVRARGHHVPVRIGIPGPAGVRVLLRFATRCGVAASASAVAKYGLSLGRLLGDAGPDRF
LVDLGKGLAAGGLGAVRLHVFPFGGFAKFAGWLGAALQEPERA
>F9EC61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. oral taxon 448 str. F0400|TrEMBL
MSLELFPPRPDRHATQTWGALDRLLAARPDFASVTYRPSFIVADPDGSRPTRRDRDEPGA
VPAPGAPHAARPPVSGAV
>A0A497XQF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenivirga caldilitoris|TrEMBL
MKIGDILRKGVFSVSFEFFPPKNEEGEKQLFETIKELRELKPTFVSVTYGAGGSTRDRTR
NVVRRIHEEIGLNVMAHLTCIAHTREELLDILKDYKDIGIDNILALRGDVPHDRPDFRPP
EGACRYAVELVRLIRDRFKDYFSVGVASYPEGHPESPNMEWEIRYFKEKVEAGAEFSITQ
MFFENTYYYEFIELCHKADINIPVIPGIMPITNFKQIRKFASMCGATIPQFLIEKMEPVE
NDPEEVAKIGVEFAIRQCEDLLRNGAPGLHFYTLNRSKATLQIYSAIRELIPVKDLYA
>A0A3A8AGB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceaniradius stylonematis|TrEMBL
MNQPRIPASIEVAPKQAIESADLPGLFPPGTRVYITDVGSDPSPTLVRAARRVRELGYEP
VPHFASRRLTTRTALDERVRATVAEAGVTDILVIGGGLERPAGAFTSTMEVLETGIFDAN
GITDIGIAGHPEGSPDFNEQVALEALRLKKNFGERTGARMRIVTQFGFDGERFARWANGL
RDNGIDMPVHLGVAGPAKVTTLIKFAAMCGVGNSLSFFKRNTRSIATLATSHSPESVVGP
IERAWHDNPTGAIRQIHVFPFGGIKKAAEWLDQRGSWDIKTSLYPHVQSNGH
>U3B3Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio ezurae NBRC 102218|TrEMBL
MGYTHASHIDALNQNVAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKTQTNLIAAPHLTCIDASRDELITIADDYWKNGIESIVALRGD
IPPNGGTPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPMTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRP
>A0A395XGX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLTEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAF
IRERRPDMKIYGACYPEKHPQADTLDHDIDNLKRKVDAGVTHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDHWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWANVQDLFA
>A0A2G1B240|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio splendidus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQIAAL
>A0A369WS95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Motiliproteus coralliicola|TrEMBL
MTLASHSEFGNPKQGLYLFGTTPPKGSTDDMQMNEISDKLLERLAGVDYDGLIVYDIQDE
SARIDKPRPFPFIGTRDPREYSALLATKSQRPIITYKSVSQRDRASFEQWLDDAWNQYGV
RNLVLVGSPSADADIKLSLPEAYQAMTEHDYPFSLGGVTIAERHAVKGDEHQRLSGKVDN
GCEFFVSQAVYDADATIALLRQYGELCQSQGSSPKRIVLTFTPCGSAKTLEFMSWLGISV
PAEVASEILEADNPLMQSIRTCQRNLERILDACQDLDIPLGLNIESLTNRKDEIDASIRL
FKLLKGTLEERLHGVTHNL
>A0A0T8EHB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIKFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2U3RYI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPTPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIELIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDIAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>J7U0S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morganella morganii subsp. morganii KT|TrEMBL
MSFLHIDQHEALNQNLAELAGRVAVSFEFFPPGTPEMEKTLWQSIERLSVLKPKFVSVTY
GANSGERDRTHSVIKSIKEKTGLIAVPHLTCIDATRDELKTIARDYWDNGIRHIVALRGD
LPDSSSKPDMYAADLVGLLKSVADFDISVAAYPEVHPEARSAQSDLINLKKKIDAGADRA
ITQFFFDVSTYLRFRDRCAAAGIDVEIVPGILPVSNFKQLQRFAGMTNVRIPGWLGTMFE
GLDDDPESRKLVGASVAMEMVKLLSREGVKDFHFYTLNRAELTYAICHTLGVRPAACVA
>A0A420HKB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Golovinomyces cichoracearum|TrEMBL
MFISDKLAEAERSGQPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGNIA
QLTVEMVSIAQSHYGLETCMHLTCTDMGKEKVDDALSGAYKSGCTNILALRGDPPRQMEK
WTRTEGGFLYAKDLVKYIREKYGNHFDIGVAGYPEGCDDQDDPELLLDHLKEKVDAGGTF
IVTQMFYDVENFLEWVAKVRAKGISVPIIPGIMPINTYASFIRRANHMGCKIPPKWATAI
ESVKNDDSAVRSIGTGLVAEMCRKILASGLIHHLHFYTMNLAQATRMVLEELNLTPSEGR
PLKTPLPWRQSLSPRRRDEDVRPIFWKNRNRSYVMRTQDWDEFPNGRWGDARSPAFGELD
AYGIGLKGSNEKNRKLWGEPKCIKDVANIFVKYLEATIESFPWSETPITSESDMIKNELI
DLNQRGLLTINSQPAVNGVKSSDPVFGWGPPNGYVYQKAYLELLVPDYLIDEILERVSRD
TDLTYHAVNIDGNLKTNTPNDAPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEAYRLGLD
WAHCHSALSPSRQLIENMMKKWYLVNIVNNDFHKTYGIYKVFEGLMVKDLEKPYSACISY
DESIPRTNGHKPKDPLTNGHMSKDPLINGLGTNKPTTNGHKISAA
>A0A1E1KRL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhynchosporium commune|TrEMBL
MHIKDMLAGAERSGQPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVSVAQSHHGLETCMHLTCTDMGQDMVDAALRDAYKAGCTNILALRGDPPREKEK
WVATEGGFQYAKDLVKHIRETYGSHFDIGVAGYPEGCDDQDDPELLLEHLKQKVDAGATF
IVTQMFYDAENFIDWIHKVRAKGITIPIVPGIMPINTYASFLRRCNHMGCRIPPEWSEAL
EKVKNDDSAVRNIGTGLVAEMCRKLLAAGIHHLHFYTMNLAQATRMLLEELNLTPSDQRP
RKQALPWRQSLGLGRREEDVRPIFWKNRNKSYVTRTQNWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNRKLWGEPKSIKDIAEIFVKYLENGVESLPWSEEPISSEADSIKSDLIA
LNRRGMLTINSQPAVDGAKSSDPVYGWGPNNGYVYQKAYLELLVSPTLMAQLITRIELEP
DLTYYAVNRVGELKTNASGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AKCYSALSPSRQLIENLMDTWYLVNIVHNDFHQTHGLFPLFDGLELKDIDVPFSSSVNGG
DTNGADTNGVHTNGVHINGVNGIKPEGKENIHLTNGASVKVSAAN
>A0A2D1ILB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. LoGeW2-3|TrEMBL
MLNFFRHLEHHKFCILVEYLTSSKTHHVVQNIASFSAFIAIADRLHSDHDMAPLEASQHY
PESVDKVLHFAGKGRDIQDFELFLQQAKAANINNLLLLTGDKLKEHCHGQEGPPRTRYLE
SVNAVMVAKRHGGFHLGVAFNPFKYAEAERDAQYLKLHKKLKAGADFIITQLGYDMDALK
QAKAFLKHYHYPQKILACVMPLSLARANFMVKNKVAGIVITPHMLKVLADEKQVGLSDRV
YLRCALQILIFKHLGFAGVHLSACHKREEQMLLESYIEQYQHLDLVALEALWNSLWQVKT
GKEFVPELPYYSRQPTSSQLIKYQQLHFMHEALFESKIAKGVGHFIFKASFWEHTPAAKA
LLKTEFISKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIKVRGTSSWKNWYLATET
>A0A7M7NX90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strongylocentrotus purpuratus|TrEMBL
MAVVTRVDQNGVPLKQVQEESALGLQNLIQSLHQNGNLTPTSLSRSPSPEPVMPFMRLSE
KIANRIASKDRWFSLEFFPPRTASGAVNLVGRFDRMFHGGPLFCDITWHSAGNPGGRKET
SSMEIARTMLNYCGLDTMLHMCCVSQSAEVITRHLEWAKECGIRNILALRGDVPGHTDEW
EPTPGGFNYATDLVKHIRKVFGDDFVIAVAGYPSGHPDAISYEDDLKCLKEKVDAGADFI
ITQLFFEAKTFLKFVRDCRAIGITVPIIPGVMPIQGYHSLRSLVKLSKLDVPQEIMDVIE
PIKENDAAIRNYGVHQAVTMCKELFESGEVFGIHIYTLNREVATIEILSSLGLWCGEPKR
PLPWKTTANLKRKQEDVRPIFWASRPKSYVYRTQEWDEFPNGRWGDSSSPAFGELKDYHL
FYLASKSNQKQLQTMWGEEITCVEDVSEIFTCYLSGEPNRYGNKVTRFPWNDDEVSSETM
RVSSQLVSMNKRGVLTINSQPNVNGEPSSDPVVGWGAPNGYVYQKAYLEFFCSRENVAAL
LHILQDYPLVNYHVVNAKGTETITNTDRLKPNAVTWGVFPGAEVKQPTVVDPISFMSWKD
EAFGLWLESWRTLYKEGSPSWHVIQFIHDTYFLVNLVDNDYVKGNVLFEIIERMLERCGN
SKGDCRVGDIEDECIATKRLKVSEEEMSLSND
>A0A1Y5IBL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ostreococcus tauri|TrEMBL
MTLVDALMDPSRPVFLFGTTPPLDGSSADAEREAAENFANKARGLAADGYIVYDIQEEKG
RTEDARPFPFRKLADPGSFAKALKRATNGGESVVYKCVAETKSEEAFKEWLADATRATTA
YNLVGGASSSQEYAGPTIARAAEMLKEANKKCAFGGVTIAERHAKKGNEHETLCAKAAAG
AEWFISQAIYDADMTIKLVNDYGAECKKRNIKPKKIVLTFAPCGREKTMKFIKWLGCSVP
EAVEQEILTAQNPAQKSVEVLVAMCARIIEETKDSGVPLGVSVESVSIFKNEKEAAHDLF
RLTQAVMLDAYGLDWSMRYTIGGKPTTKTEKPSITERQLGDENVAKRVAIATAAFLAGVA
VRGVTSRR
>A0A6P0IPT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO3I7|TrEMBL
MTNPTKNSFRTAVESGEFLITAEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQQGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFEK
KLEAGAEFFQSQLICDFDRLEKFMDQIAAGTNKPILAGIFLLKSAKNAKFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSAINDLVCK
>H9GT71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anolis carolinensis|TrEMBL
LLSIGNGFTSLRPDGGGGGSGSSGGESSKESSRCSTPVLEPERHERLREKMRRRLESGDK
WFSLEFFPPRTASGAVNLISRYENASGIHA
>A0A2S2CQC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum thermophilum|TrEMBL
MTSAASSAAPAVSFEFFPPKTEKMEQSLWQAIERLAPLRPAFVSVTYGAGGSTRERTHAT
VCRIQKETGIPAAAHFTCVGATREEIDSIARTYWEAGIRHLVALRGDPPESAGGIGGRYE
PHPGGYAYAADLVAGMREVADFEISVAAYPETHPEAPSAQFDLDNLKRKVDAGATRAITQ
FFFDNDAYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCNASVPQKLADTFDGLD
SDPETRHLVAATVAAEQCQALQAQGVNDFHFYTLNRADLTVAICRMLGVKAKAAAPSPAP
AA
>A0A135SX92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum nymphaeae SA-01|TrEMBL
MHIKAMLDESRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREQEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGATF
IVTQMFYDGDNFVRWVGKVRERGITVPIIPGIMPIATYSSFLRRAKHMNCKVPEEWMAAL
EPIKNDDVAVREVGKGLVAEMCRKIVAAGIHHLHFYTMNLAQATRMVLEELEWMPTSDRP
VKHALPWKQSLAHGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSVKDIANIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSTHPVHGWGPANGYVYQKAYLELLVHPDVYHEIVARVEKNP
DMTYYATTKTGNLKYNASNDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGIDW
AHCFEAGSPSRTLVERIMNEWYLINIVNNDFHQKTALFDLLEGLEVKEYSDISAEPQTNG
AAKEQQTNGSAPAAAVAAN
>A0A2E9J1C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. NP17|TrEMBL
MVRLSSVLQSSLEAGAVTITAEVMPPRGGDASHALEMARSLRGRVHAVNVTDGSRAVMRM
SSLAVARLLLEEGIEPVLQMACRDRNRIAIQADLLGAHALGIRNLLCLTGDPVRAGDQPK
ARHVNELESVRLLEQVSALNRGEDPVKGDLVDGPTSLFAGAAADPQCLSWTGLARRMERK
KAAGACFVQTQMVMDAAALERFCREIAEPMQLPVLAGVFLLKSARNACFINRMVPGACIP
DNLIARLEAAEDPAAEGIRIAADQVKQYLGLAQGVHLMAIKAEERIPTILDQAGVSLIA
>R6QD72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:251|TrEMBL
MKIKDIINNKKVTVSFEVFPPKQWDKIANTKKIVEEMVKDKPSFMSVTYGAAGTTSGFTT
EIANAIKEGGVEPLSHLTCLTSTKEKIDSVLDELEANGIENVLALRGDIPKDFEMGENQY
FHHAFELVNEIKARGKFCVGAACYPETHPESKNRVEDIARLKEKVDCGVDFITTQMFFDN
DKFYNFREMCAIKEINVPIIAGIMPITNANQIKRSLELSNASLPAKFNKIMERFGENPDA
MKQAGIVYATEQIIDLMANGVNNIHIYTMNKPDVAHQIMEGLSAIINE
>A0A3Q8ZJN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M4B.F.Ca.ET.058.02.1.1|TrEMBL
MTIRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A376CQV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium minutissimum|TrEMBL
MSPRLSASAPLDQISEDTPKRLERTALSFEVIPPRHDADAAKIDRLLATLSAYKPDYIAV
TSSQRSGWLKGTAAFIEKISRDTAMRPLAHLACTAGTEEELIGWIDTLVDAGVRGLLALR
GDLPEEGMPEGHLPHADSLVRLIRRWESARVARLAAGRLAVGVACYPNGHAESATPDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTKVLDRLAAATSPEEEQEIGMQITASLAQSVLNAGADGLHIYTHNNPDITTDLL
NRIGVTP
>A0A851N098|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylorhamphus procurvoides|TrEMBL
MVNEAQQSCSGSSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDR
WFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCSNQTKEDITGHLQKAKRLGLKNIMALRGDPTGEEWQEEADGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAECYETDLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVVEPIKDNDAAIRNYG
VELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIHRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVMEDTFELLN
>A0A7L3BZ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelecanoides urinatrix|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKESSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPDAESYEADLRHLKEKVSAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKCLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A4P6JHW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ktedonosporobacter rubrisoli|TrEMBL
MNTTSPFLTHLRHGPLLCDGGMGTELHARGVPYEHCFEQLNLSSPELIKGIHLDYIAAGA
QIIETNTFGANRYRLAEHGLAHAVREINRAGAKIAREARELSDLPIFLAGNIGPLGSPLA
PLGSIKETEAYAAFLEQAEALLQAGVDLFLLETFSDITEMRAALSAVRNITDLPIVALMT
FTDDGRVASGEDPQVVARTLQEQGADIVGVNCALGPSSMFDVVAAMCHTTSEQLFIAAQP
NAGLPKRVGNRFMYIATPDYFATYARRFLDLGVRLIGGCCGTTPQHIAAMRKVLDESVPQ
EGRAQNVKIEPVPEALQEHKVHPPENDPGIVQTTHLADLLLKENFVVSVEMRPPRSVKYT
RFLQNAALLRDGGADIINIPDNAMARVRMNNIAAARLIQQYVGLETIVHFTPRDRNLMAV
QSDVIGAHATGIRNILAITGDPPGHGDFPHATGIWDVDSIGLIAMMHNLNQGLDAKGRRL
AAQSSFYIGCAANPTATDVALDLERLQQKIESGAMYVMTQPIFDANALLDYLEQYTQRYG
ALRMPLIVGLQPLHSYQQAEKFHNEVPGIVIPDHIRARLYQAGEAASRVGIEQTMEVFDA
LAPIVQGVYIMPLDRFELIHELLPYIRSRKAACAKSTV
>A0A8I0SR48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetococcales bacterium|TrEMBL
MRFRSWSLKVCGLAYEEIDVSADKNGSMISFELVPRDSATLTAELELIKNRFPEVDLINI
PDLPRFDKRSWEGCAVARQYFSVAIPHIRARDCDPQRPLAMAGFLRDHGIGQVLVVTGDT
HPDPFFPQFNVRAVDVIRKFRVEMPEVKVYAAIDPYRSGFQGEMAYVREKMNAGAAGFFT
QPFFDLRLMEVYGELLHGMEIFWGVSPVTTVQSQGYWEKRNLAIFPRAFKPTEEWNLDFA
HKAVTFAKRHGQHVYFMPINLDLPSYLNGLFPKVTEGIIG
>A0A2A3EME8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apis cerana cerana|TrEMBL
MKKTILKRKTYNQYIDNIKNGYQFKDTEYEIIDLRNKLKNVIDTNTIFCSFEFMHVENND
FYKSFFMEMNKYHPLFYALTWKHMKNEIKNYLSSDICNIFPNNILLHLTSNDLTRNDVKI
ILKKTLDRGIRNIFVLKGDSSNPNSEFPYAIDLVRFIRNQFGEIFCICVAGYPEMHPKSL
SKEMDLVYLKEKVDAGADFIITQMFFEANIFIKFVNDCKQIGINVPIIPGIFPIPNYICF
QKMAKICNVKIPQIILNDLQCIKDNDEEVRIYGIELLKTIIKDIIASKTTCGFHFFTLNK
PSLSSKICDKLGIFY
>A0A3A9Z292|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces hoynatensis|TrEMBL
MALGTPSTRKDRAHTVRELLAAGECSFSFEFTPPKTEQGERTLWNAIRRVEAVGPTFVSV
TYGAGGSSRERTVRATEQIATETTLTPVAHLTAVNHSVAELRNIVGQYAAAGIRNMLALR
GDPPGDPMGEWTRHPEGVTYAAELVSLIKEAGDFCVGVAAFPEMHPRSTDWETDLRHFVA
KCRAGADFAITQMFFDPADYLRLRDRVAAAGCETPIIPEIMPIANVRQIERFKQLSNSTF
PPELERRILAVKDDPLAVRSVGIDFATELCARLMDEDIPGLHFVTLNTTLHSTATLDVYK
NLGLHQRT
>A0A2N3RFS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas prunicola|TrEMBL
MISTDTPSLATTIADTVADAYSLEVSVNDIGALTKAAPRILPGSAIFIPYLPGQHDAERL
AAARMVRGLGFEPIPHLSARRMTSLAQLQALVARAVDEAGVRCCLVIAGDPSIQKGPFPD
SLSLIDTGVFERSGIRTIGVAGHPQGHPNMRTAEQWDVLERKCRSIQQRGMAPLIVTQFG
FDADSVVTWVEALRARGMTHPVRVGVPGPASVAVLARYAARCGVGACASVLSNYGISIGK
LFGNAGPDRFVDRLASRLTQAHGDIHLHLFPFGGIAQSVEWVAHYRSRNAPQDRTSAVRA
DRA
>A0A2N6PRG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. UMB0029|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLVIPTIAHLPAIYLNKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGVDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A2N3RKM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas prunicola|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAVDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCQRLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1V2RFQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MP131-18|TrEMBL
MSTVRDVLAAPGRCYSFEFFPPKTEAGERSLWRTIRRVEALAPAFVSVTYGAGGSSRSRT
VSVLHRIIGETTLRTVGHLTAVGHSVAELRNIIGQFADAGIRDILALRGDPPGDPRATWA
PHPRGFTHAHELVRLVRASGDFGVGVAAFPERHPRSPDWDSDIAHFVAKCRAGADFAVTQ
MFFHPEHYLRLRDRVAAAGCDTPIIPAIMPATHARQIRTFAELSNASFPAELARRLAEAG
DDADAAHRIGVDHATELAQRLLDEGAPGLHYLTLNKSAATVEIHRNLLGAGTLAAPAG
>A6DQ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaera araneosa HTCC2155|TrEMBL
MTKISIELVPHAAEEITCELKGIQEAFPKVNTVNIPDIVRLPTRSWEACGFCAPMLERDI
PHLRACDFDLSKAQLLHDIMAEYKFDEVLLVGGDFFEGREHFDTSTVDFIKFFKTNYPDV
KVYGAIDPYRADFETEMKYLKEKMAVGIDGFFTQPFFDLELLAKWIEALKDQVVYWGLSP
VLSAKSQAYWEKRNLVNFPKDFVPELEWNAQFAADAIELIDKYNSCLYFMPIRIPVVDYL
NAIIPKSKILGSLLR
>A0A2D9N7H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altibacter sp|TrEMBL
MKVLEHIAKANGKTQFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYVYKE
LENGLLEKKVVRKRPGTVGICAAIQNKYDVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKNETYFTPEKKGHAYAEELVKQIEALNRGTYLDAETLNQAQTNFCIGVAGY
PEKHAEAPNMESDIHFLKKKLKNGGAYVVTQMFFDNAKFFQFVKKCREAGIEAPIIPGLK
PLSSKKQLNLIPQRFNAELPDALIQEVLKCKDAEQVKNVGIEWCVMQSKELMAEGVPFLH
FYSMGKSDNIRTVASQLF
>A0A0M6YHB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jannaschia donghaensis|TrEMBL
MSAPKVSFEFFPPKSLAGSFRLWDCVSTLAPLAPEWVSVTYGAGGTTRDLTREAVGALGQ
AFDLRVAGHLTCVDASREETLNVARDFRKAGVRDIVALRGDPPKGADGFVPHPDGFRTSV
ELIGALADEGFTVRVGAYPDVHPEATDAGADIDWLRAKIDAGASEAITQFFFDADTFLRF
RDRCAAGGIDAPIVPGLMPIEDWAKASRFADACGAVIPDDLRAAFDVALRDDRADLLAIA
QAAELADALVGEGCEHLHFYTLNRPELTRDVCTALGLAPRPALRDVA
>A0A5F0JNA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. A11|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A2E8TQP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MCKGLPESFFFINFFQVIRSNFYYQLKSDNTIKTSIRKLNIFSQSLDTKDFTISSEIFLR
PDTDREAIKIQAELLKDHVDAILLTDNQSGQLHMSTLSAGIILKENGIDPIINLSCRNRN
RISLTSELLGCASLDMKNLLLTRGEKIPKEVEPRPKAIMDMNADALISLANKIKMDEKLP
TNNDFLIGGVVTPFVPKSGWPAKNLTEKVEAGVQFVITHTCLDMEIMKIYMERLIATKLL
RKMHLIVGIAILKSAXDAKWLRENRPNVIIPAEAVSRLENSKDPEKEGIKMCAEQLTALS
KLPGVSGAHVIASNSVLNIPEAIASFEAQK
>N1P5B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain CEN.PK113-7D)|TrEMBL
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRD
AENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDVKLDLEYLKQKID
AGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQH
FSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANKCLELWSTPTSINDVAFLVINYLNGNLKCLPWSDIPIN
DEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL
>A0A1H2CPF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas umsongensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLSQYKAAGIQRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A4P9EUN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus paranthracis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6I6FIH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces ficellus|TrEMBL
MALGTPSTRTDRARTVRDLLATGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATQEIAADTTLTPVAHLTAVNHTIAELRNMIGQYADADIRNILAVR
GDPPGDPMGEWVPNPRGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFLPEDYLRLRDRVAAQGCETPIIPEIMPVTSVKQIERFAQLSNAHF
PPELKERIHAVKDDPAAVRSIGIEYATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHEQS
>X0XI42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MNDLKSGSNLEKVLRAGHFAFTGECGPPKGANIDHLKEKIAHLKGMVDAVNITDNQTAVV
RMSSWAASTILIQEGIEPNFQMVCRDRNRLAMQSDILGAYAMGIRNILCLSGDHQRFGNH
PQAKNVFDIDSMQLIALAKKMRDEGKFLNEEELDVSPRLFIGAASNPFADPLEFRV
>A0A6V8IIV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter sp. Gdi|TrEMBL
MTVSVGRVRAELMKESSIELLPSRILELSGVLPDLACGSRVFVTWLPGVPFADVLAACDL
LKLCGYLPVPHVAVRSIRNKDHLQEICTALSERDIPRMLLIAGGAEKPAGIFADTVQVLE
TEIPVRTGIRTVYVAGHPEGHPQASEATLLEYMRRKQDLARAQGLNMQIVTQFCFDAAPV
LAWEKRLREEGITLPINLGVYGLTTPKTLVRYGLACGVGQSLRFMQRQRWKLHRWFMPCN
PLPLVDAVAREVAETPNTNFRGLHFYPFGAIARTLEWRRTLSLSTGDHS
>A0A2R5GQZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hondaea fermentalgiana|TrEMBL
MTSGSRLIERMKARIADGEVFHSFEYFPPAKESGRKSLQVRVDRMADMSPLFVDVTARAG
NLEDTLRLCSDIIRFCGVDVMMHVTSAGLARADLVDLLQRALEAGITNVLALGGDPAGKT
LRPSGDFAHALDMVRAIREDFGDAFTIAVGCYPEGLGPLSSNESWTENRARHIGYLKEKV
LAGADFAITQAVFDASLFVNFVRDCHQAGVSADFPILPGIMPIHNYKGLKSIVSDLNVSL
PETFESALAPIQNDTGAVMSKGIELIGDLCAELLSSDVTAGLHFYTFNLEYAVRQLVEKR
LALDAKQVLPWRQSANPRRLEEDVRPIFWANRPKSYLMRTEGWDQFPSGRWGSGQPGENF
AMLPDSEPMFSRETFFQRQDIMRKAWGEAPQTEQEIFEVFAGFLEGRVPFLPWCEESLHL
ETSQIRDKLVALNRAGYLTINSQPRVNAAPSSSPDFGWGPGGGYVYQKAYIEFFTSPRHL
RRLMDLLESPEFSGRSLVYHAVDHRGNTYSNDKQAKPCAVTWGVFPGKEVIQPTVVDPDT
FLVWKDEAFGLWVRGWASIYEEDSSSYNLLYDMHDGYFLVNIVDNDFIDGDIFDLFDRLV
AGREHGGHEETYHGYEYDQTSGNLTHYQLEDWASASQADVQGNESSTTHYYENNSFYPEQ
NRHYSEQDAQAFLRSSSSSSNNNNNNNNNNIDDDSASVATHEAYGYDAYSVASSYYDSQG
GELGHGYDAVPSSSASAYGGDYYEHKMAENGYSGYESATVYAHTPSHMGYSSRTDMSSRS
APPPPYYNDQHGSSIHSSYYDQGYAEYYRREQERQRLLQAQQEEALQSSSEVPNIFSLTR
HNRYDDVEALFDAGIAVDTRDALGNTVLCIACQNGLKRIAKLALRRGANINAQNYRGNSP
LHFCYMYQYGDTLGAYLLSKGADPMLVNSDGRRSHELE
>X0S835|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MALQAELLLAYTRDIRNVLCLTGDAIPVGDHKEAKGVFELDSVQLLRTIRQMESGKDLGG
NDLDGAVEFCAGAIVTPEANPIEPQLIKFEKKVEAGAEFIQTQAIYDLENFSKFMDYARQ
FHVKILAGIVLLVSARMAKYMNDNVPGIFVPQNLIDELASAPKGEALNKGIEIAGRMIAT
LKKDSICDGVHIMAIGREEVVPDILAAAGIDGHSK
>X1SA94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
FAAGAKFFQTQAIYDVGAFTKFMDRAQRFNVPILAGIIPLKSAGMARFMNRNVAGVFVPD
TLIDKMAKAEDKVQVGMEIAAGLIKELKDMCQGVHIMPIGWEKKVPAMLDAAGL
>A0A7V7QJ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Galacturonibacter soehngenii|TrEMBL
MNVSEYLEKKPLIFDGAMGTYYGERYTGKCEYANIEHPNRVLQIHKEYIEAGCMAIKTNT
FAANTVSLETDIEIVKKIVAAGSRIALEAAKERDIAVFADMGPIPYVGGSPIQEYKEIID
VFLENNITNFLFETLGSDEDLAELSRYIKRKKEDSFIIVQFAVTPDGFTRVGLSGKNIFK
RINEIKEIDAVGFNCISGAHHLYEYIKQLEPFQKNISIMPNAGFPTVRDNRTIFENSSDY
FAETLYKTINVGVNIVGGCCGTTPEYIRKTVEYVKGVKTAKRIEYKKAEVTKRESNQKEN
LLLHKINAGKKIIAVELDPPSKAEISNFMEGAKRLKYSGVDAITIADCPLARARVDSSLL
ACKLKRELDITPIPHMTCRDRNINATKALLLGLNIEGVENVLVVTGDPVPSPLRDEIKTM
FSFNSAILAKHISELNEEVFSSPFGICAALNVNARNFDAQLKHAQKKIDNGVTMLFTQPV
LTEEAFENLKKAKETLQAKILGGIIPIVSHRNACFMNNEISGINVSQDIINQYEGKEREE
ASKLAVKISTEIAEKISPYVDGYYIITPFNRVDIIEKIIQGIHTFQS
>A0A8F7L9A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus globerulus|TrEMBL
MTFDAVRGRSSDGWASRTPSIVDRITSSTGSRIPFSVEFSPPRDAEAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSIDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPDGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
HDTKYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAFDPEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGSQENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTSDVSTDSQASV
>X0VJF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
PKGADVSEMVHHIDLLKDNVDAINVTDHQSSVMRFPSLGGCLLVKERGGEPILQVTCRDR
NRLALQADLLLAYSRDICNVLCLTGDSIDVGDHKEAKPVFDADSVQLLRMIRTMESGKDM
SGEDLKGALKFCIGASVHPEADFIEPQLIKFEKKVAAGAQFFQTQGIFDLASLRRFMQYA
SQFDVRILAGIIVLASSRMARYMNDNVPGIIVSEAIIDELAGVEKGKGLEKGIEIAARLI
KTIKEENLCHGVHIMAVGNERIVPEILEQ
>X1KYE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
AIFHITCRDRNLLGLQAELLGASALGVKNILALTGDPPEVGDYIMATGVYDVDSIGLVKM
VNKLNNGYEYGGNEFKDKTDFFIGIAVNPTAQDLTKEIKRFEKKVSAGANFIQTQPIYDI
RLLERFLKLTAHINIPKIIGIMPLKSYKMVEYLNNNLPGIFVPPGVKERMWGKDVEEGVK
ISRELISEIRKFKEVAGIHIFPLRDMDLVCRLLN
>A0A847ZH57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp|TrEMBL
MPENRFKEALLDPSEFPVTWELVPGRGAKEAAQEKCLAQAEQAAGGHKACALTLTDNPGG
TPAMSADFMGAEILKLGIEPLVHFTGKDKNRNQCESQLYALDRAGVRNLLVMSGDYPVSG
FQGRPAPVFDLDPVHLLQLITSMNRGLTYPGIKGAVTHQPADFFPGAVVSPFKATEAEQM
GQYDKLKKKIAAGAQFIVTQLGYDARKFHEALLFMKQNYPQIPLVGNIYILPFGAAKMMN
RNDLPGSVVTDQLLADIDRERSDPDKGEGARILRAARMYAILKGMGYSGVHIGGHNIRYE
QVEEITRQGEMLVPSWTELVRYFHYPIDNGFYFFEANPATGLNRDTPVDRRSRPLETKVE
CAYGFSRFFHRLMYEPGKNLYGAMRALCKTVQGTRMEPLFHKLEHFTKVALFDCRDCGDC
ALPDIAYLCPMSQCPKNQRNGPCGGSFQGWCEIYPKQRLCVHVRAYARLKKHGEESRLAG
NIVPPCNWDLYQTSSWINYYLGKDHTSAKQGGTGSPGIP
>X1KJK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
ASAGMARYMNNNVPGIIVPQATIDELASTEKDKRLQKGIEIAAGLIKTVKEENLCHGVHI
MAVGNERIVPDILEAAQLTGVRH
>A0A0N9UTC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis macrogoltabida|TrEMBL
MTSNLDSLAEARRAAASPLFANLDGDIGVSFEFFPPKTEKMEAQLWDTFHALEPLAPRFV
SVTYGAGGSTRERTHATVARIAATSGVPPAAHLTCVEASRAEIDAVAEAYWEAGVRHIVA
LRGDVPSGGPYRPHAQGYANAIELVAGLKAVAPFDISVAAYPEVHPDADCAQSDLDNLKR
KLDAGATRAITQFFFSPDSFLRFRDTAAAAGITAPIIPGILPVSSVAQTRRMADMCGTAI
PAWMVSLFDGLDDHPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVATAKDQAA
>A0A3M7C8B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMSYDAEIFIEWAKKVRAAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAELFVKYMSGKVETLPWSEQPISPES
>A0A1G6CA16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcaceae bacterium FB2012|TrEMBL
MDLKQFFAPGRPCFSLEIFPPKDHQGGVETIYETLDGLREVHPEFISCTYGAGGNLADSS
TIEICSIIKEKYGILPISHLTCVNNSKENIGVIMDSLKEKGITNILALRGDLKPGQQPEK
DFAHASDLIFYIKERDPEFFISAACYPEGHPDSGDLITDVLDLKKKVDAGAEHLISQLFF
DNEDFYRFRDRCELAGIDVPIEAGIMPVTSKQSILRMVSMCGASIPAKLAKILNRFEDKP
KAFEEACIAYAIDQMIDLISNDVDGIHLYTMNKPYIAKRIFEVIDPMR
>A0A261UM20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella genomosp. 11|TrEMBL
MTDTSTPAYSLEFFPPRDIAAQERLLRAAKQMLAIHPRYVSVTFGAGGSTREGTAGTVRM
LRNLGVDAAPHLSCVGATRENLRAILASYRDEGVRQVVALRGDLPSGMGGDAGELKYARD
LVAFIRQETGDWFHIEVAAYPEMHPQADSPSSDLDHFIEKVRAGADSAITQYFFNPDAYF
DFIERVAAKGVSVPVVPGIMPITNHTQLARFSQMCGAEIPRWIRLRLAEFGDDKASIRAF
GVDVVTDLCRKLLEGGAPGLHFYTLNSAEAPMAIWKNLAGA
>V9DDB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cladophialophora carrionii CBS 160.54|TrEMBL
MAFGHDDRLPTLFSSLDPSSHYFSLEFFPPKTSSGFSNLQSRLARMATALHPLFVTVTWG
AGGSTATKSLELAELCQRQLGLTTVLHLTCTNMKKDMVDEALEAAKEIGIRNILALRGDP
PREEYKDATSLGETEGGSGGAGTGSNEEFTWAIDLVRYIRRKHGNYFAVGVAGYPEGHAD
ESHPEQGKQSVEHDLPYLVGKVSAGADFIMTQLTYDIDAYRRYEDRLRNYADPEGRRVFA
KIPIIPGLMPIQSYQIIKRITKLSHARLPEDISKRIEAVKSDDEAVKKVGVDVLSELVEQ
MKTLPQPDGVPRGFHFYTLNLEKSVAFILERTGLIPPVSSEGSTGDRDGDSSSDPDAVVD
DDKRDGTATITKEQADQDAHQARDSAFSRRRRSSINAQPHNRVIMDRPSRSPAQARPDGD
TDPPNGRSSSLTAQHSARDRGTGIPASSPTRRHNLLISEGQGSLGREATWDDYPNGRFGP
SHSPAFGEIDGYGPSLKVSPLMARKLWDHPKSAKDVTEIFRRHVSGELAGVPWSDDIDPS
GGNGTTLSKDTAGALRAETDVIRSELLSLISKQNYWTLASQPAVDGAPSSHPIFGWGPPG
EGFVFQKTFVEFFCSRDEWETRLKDRLQKYGSEVLSWMKTDVHGAFESAQHAPRPANGVK
RAATDETTNPISTMNINASAGVSDVDTVNAVTWGVFPSREILTPTIIEAESFRAWAQEAF
AIWSEWKRCFPRGSEEAAFLDRARGDVVLVNIVGQEFRGGHDGQGGRLWKILLGEDQKMG
ERSGLDDT
>A0A348W431|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp|TrEMBL
MRENLFKEALLNPSVFPVTWELVPGRGAKESAQEKTLSLAKQAAESGKICALTLTDNPGG
TPAMSADFMGGEIVKLGIEPLVHFTCKDRNRNQIESQLYALDRAGVRNILVMSGDYPVSG
YGGR
>A0A081CL87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudozyma antarctica|TrEMBL
MVCSRALGSSVAQPPSCVASLGTMPESSMAASSSNSTPGAHAAAAPNPAHITAKIQQANA
RDAPFWSFEFFPPKTTQGLANLYSRIARMRANLDPSWIHVTWGAGGTTVEKSLELAGRIQ
KGRLDPATPLLSPNGQNGSEAGEEWQHESADACDVCLHLTCTNVQKASLDETLLAAKRLG
IRNILALRGDPPRGEEYWVAADERFQHATDLVRYIRDSHGDHFCIGVAGYPEGHADYVDR
DVQRDLAFLKQKQDAGAQYIVTQLFYDVDRFLAWYKDARALGITIPILPGIMPIQNYQSF
RRMTNLCKVQIPPLVLEALEPIKADDAAVKEYGVALSIHMIGRIFLESDVRGFHLCSLNL
EKSIERILDGLGWKTDVGALGEADVRLSVVPAHLHLERTKNQMLSDRTGANTPRDFKVTT
QEALKRTLARTSSSYQVPETTTWDEFPNGRYGDSRSPAFGEMDGYGVSLKVPAADALRIW
GHPVTLSDISTIFASYLEEKIACIPWCDAPLMNETLQIRDHLLALNRLGATRDAGKGWWS
VGSQPAIDGAPSTDPVVGFGPAGGFIFQKAFVELFMSGSDKDALVEAIDAMGPHAQYTYF
AGNTRGDFVSNLAEGEANTVTWAVFPGKEIVQSTIIERDSFEAWREEAFGIWNEWAMLFL
KTSASRQLIDSITNDRWLMTIVHHDYKDAQALWKFLAQ
>A0A7Y3MRT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
LSGGTRFPAKLLKGIYKRQDDPEAVAQFGVLWATEQCRDLLDHDVRGIHFYTLNRSDATR
RIFETLGAKDSTALR
>N9M435|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 713|TrEMBL
MPQLSCYFQKNQFCILVEYLTSLNQVFPLKTEFAGYPAVMTLADRVHSDHDIAPLAASRY
YPDSVEKVLHFSGKGRDIQDFELFLQQAEAAKINNLLLLTGDKLKEHFHGQHGSARSRYL
ESVNAVMAAKRHGGFHLGVAFNPFKYAEAERDAQYLKLHKKLKAGADFIITQLGYDMDAL
KAARNFLKHYHYPQKILACVMPLSWARANFMVKHNVAGIVITPHMLQVLADEKQAGLSDR
VYLRCALQVLICKQLGFAGIHLSACYQPEEQMLLESYIEQYRHLALEELEALWNSLWQVK
TGKEFVPALAYYSRQPTSSQIIKYQQLHGIHEVLFDSTIAKGVGRFIFKVSLWENPAAAK
ALLKTEFISKHGIVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVGQTESLKEKLIPTVPLEVRGTSSWKNWYLATKA
>A0A2E0UVY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MPGFTPGRRWQPAYYPYHKESLFDRTLETVERAIKGLLFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGSTAEHCYVDPSRPCIWYKIYERSEKMGRTEKLMEVLPPLDWDMVGTDSW
KGLFLHMQENGGIKAIFERLRLPGDERADAWEKFFYDLRQPDWWQGDDQPHPAPAHKPVS
VLEEKLTNGEFVVTAEVAPPIAAETEHLIKKLEALREVLDAVNFTDNPSATPRMSSFASS
LLALQVGLEPVMQIAARERTRMGIQAEILGAAALGIRNVLCITGDHASMGPSPHGRLDIL
DLDSVQMIWMLRRMRDENHFLDGREIKSAPQLFLGAAGSPFASETRFQAVREKKKSNAGA
QFFQTNLIYDPRRFQDYLEALDKQGVLEQSYLLAGVAPIRSYKAAKMMQNIPGIEIPDSL
VTRMEKATDGKEEGIQICLEIVEQVKNLPGVNGIHFMAMGWESIIPRLVRDSGLAPQ
>A0A242U1P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MLVEYLTSLHEIYPVRREFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGK
ARDIQDFEFFLEQAKSANVQNLLLLTGDKLKEHHNGRDGQLRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKNNYSQ
QILACVMPLTLGRANYMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKH
SGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVKTGKEFTPEIARFSR
QPTSKQIIKYRQLHVMHEAMFGSKIAKGVGRFIFKAPFWENSVVAKALLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKQT
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A7C3KAB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHFSSLFQSRSTTFSFEFFPPKTEKSAAELFDAVTELQSLRPSFVSVTYGAGGSTRELTQ
DLVIRIREQTPIEVVPHLTCIWHTEAEIYDILERYAEAGIENILALAGDVPREKPDYDRS
RDAFRHASQLVRFIRQFKDRHGGRSIKDPRGFGIGVAGFPEGHPGCPNRLVEMDYLKAKV
DEGADVIITQLFFDNRDFYDFRDRCRLAGIKIPIIAGMMPITSVGGMRRMAEMAAGARIP
AALLKAVGRCGDDADAVRRVGVHWATEQCRDLLDHDVAGIHFYTLNKSTATREIYATLGV
KDSLALGGLGASGAR
>A0A7Z9LU97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lambdaproteobacteria bacterium|TrEMBL
MEIPFRESDTLENDMFMEPADDLQDYLKQKTTWSMEILPHNINDVSLIPEFVNEVYITMI
PGASCWETIQTAQQIKAVGKQAIPHIAARSFADVEELSACLSELQEAGIERALLIGGGNS
EPAGDFSCVMDMLKTGLLTKYGINSYDFAGHPEGNPDDPNSEFHLLEKLRWTEERGISTR
IVTQWCLDTDSANDWISGLREKGIRNPIHIGIPGPSTIKTLMRFAKVCGVKASTQVLRKQ
GLNLSKLMFVNKPDKIISELRGYDQLHLYPFGGIEKSAAWLTERQKAND
>A0A4V2DBZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium corticibacterium|TrEMBL
MKIVDHIKNANGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYLYKQ
HVSGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDPDFVPTPGGHAYATELLQQVVDMNSGKYLHEDIESSAKTDFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVTKCRDHGIHVPIIPGLK
PLTTKRQLITLPKIFHLDIPEELSEAVENCTTNADVRQVGEEWLVEQCKELIKFGAPVLH
FYTMSNPGPTKKIVERLA
>A0A6N7A7Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MPIFTPGRRWQPPYMPFKREKFGPRLLASVEKAVKGPLFGCRMCGNCLLQETAFICSMEC
PKGIRNGPCGGSTPEHCYVDETRPCMWYKIYERAFKMGRQEMLLEVLPPLDWDKVGTETW
GDVARQVKKVGMKNVTSGLLARDPVTRTATWDSIFRPVRQTEWWQGDSEYHAPKYSEPAS
KLEEQLKAGEFVVTAEVAPPLTVSINKLCSNVEMVKPYVTAINFTDNPSASSRMSSWACS
TLATQHGAEAVMQIAARDRTRIGLQSEALGANALGVRNILCLSGDSMRLAPTPRGRMDVV
DVDAVQMLWILRRMRDEGKYMDGRAIKFPPKYFLGAAAAPFASDPRFQALREHKKVNAGA
QFFQTNLVYDPDGMEIWLNELAKRDVLNKVYILIGITPLKSFKIAKYMDDEVPGVFVPEK
LLKRMEAAEAAGNAQEEGVQIALEIIEKIKARFGQGVHGIHIMAVGWEEIVPRIVRDAGL
LPKGFVEPAPAEKTAAPA
>A0A388NSA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MTSINLQEKLRRGTLLADGALGSELYARGIIHGSCLDALNLTDPAAVLGVHAGYLQAGAD
LIETNTFGANPFRLASHGHAEQVAAINQAGVVLARQAAAASGRAVAVAGSVGPLGVRLAP
FGRVKPEAAYAAFSAQIGALLAAGVDALVLETFSDLMELSEAVRAARDCAAAHPPVLLVA
SMTFTRDDRTQLGDSPAHVARTLAGLGVDVLGANCSIGPAQLLRVLKGMHAAAPQLPLSI
MPNAGMPELSGGRVVYPAGPDYFAQLTPDWLATGARIVGGCCGTTPAHIAALRQALDTPR
TASVRSVPARPSSPAESLPATDEPTKLATQLQSKRFVITVEMSPPKGYTPHKVLAGAHML
AEAGADVINVADSPLARMRMSPWAVCHLIQQQVGVETVLHFPTRGRNLLRVQGDLLAAHA
LGVRNVFVVMGDPANIGDFPQAFDTFDVAPTALLQLVKQRFNAGMDQAGQDIGQPTSFVA
ACALSLSAPDPAREIKLLRKKLECGADFALTQPVFDAQVARDFFARYAAEHGPLQLPVLV
GVLPLYSERHAGFLHNEVPGVHIPEAIQRRIAGAADAPAEGIRIALELLAELREITPIRG
AYLQPPFRRYELAAEIIEHLRAQD
>A0A3G6XY56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGK
ARDIQNFEHFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVTSGKEFSPEITYFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGIGRFIFKASFWENALVAKVLVKTEVLSKHSLV
GCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQT
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A3B0FQZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter phenanthrenivorans|TrEMBL
ELSDVGYTVVPHLAARSIRSRAELTGIVRGCDAAGIREVFVIGGDRKQAAGNYDSALPVL
EDIAQYTGGLMLAGVAGYPEGHPAVSPLDLLDGLLAKQHLATHVVTQMCFDAGKIHDYAA
LLRREGVNLPVWAGVAGSVPRTKLVALATQIGVGSSLKFLSRKGPLARKLLSGDRYSPAS
LVTGLETQPGSIAGIHLYSFNNLDAVPTDVAASSPSALQAVDSRSST
>A0A2N2ADC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium HGW-Gammaproteobacteria-1|TrEMBL
MESQKKYRQGFSFEFFPPKTPEGRQKLLVARDKFAALKPVYASVTYGAGGSTQQGTLETI
RDLIAGGLDAAPHLSCIGSGSDDIRALLQDYIALGVKRIVALRGDMPSGMRDTGEFHYAN
ELVEFIRSETGDHFHIEVAAYPEFHPQAPSAQKDLQNFKRKVEAGANAAITQYFYNLDAY
LRFVDECERMGLQLPIVPGIMPITNYKQLARFSDACGAEIPRWLGKRLEGMGEDLESIRA
YGLEVTADLCRRLLDAGAPGLHFYTMNQFEPTHAIWQALGLPR
>A0A0D6PDL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidocella aminolytica 101 = DSM 11237|TrEMBL
MTHSPDRHTLERWAAGERIAPLPARDGAAPPAISFEFFPPKTEGLEAQLWHCIERLATLR
PDFVSVTYGAGGSTQERTHATVLRIVKETALTPAAHLTCVGATKEDVNAVAERYWQAGVK
HIVALRGDMPGGAPYTPHPGGYAFAADLVEGLKKIAAFEISVAAYPETHPQAASPKADLD
NLKRKLDAGATRAITQVFFDNNIFLRFMDRALAAGIKAPIVPGILPVTNFNQARKFCEAC
GTSIPQWMAGMFEGLDDDVETRRMVAAAVAAEQVRLLQANGIDEFHFYTLNRPDLTYAIA
RILGVKPDPAA
>A0A165RX01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Daedalea quercina L-15889|TrEMBL
MKLTEKIAKYDRDRPWFSFEFFPPKTDEGFENLLSRIARMLTFDPLALSITWGAGGNTKD
RSLELAGITQSDHGVDTILHLTCTNMKKGMIEEALRDAKARGIETILALRGDPPRGQEHW
IPTDPRFTHAVDLVSFIKTTPEFASDFCVGVAAYPDGHPDRETDEEGELEYLKQKIDAGG
EFIITQLFYDVHSFLSWVKKVRQKGITVPIIPGIMPIQTYASFLRMTKLCGTRVPPELMA
DLVPIRHDDQKVKDYGVDLAVNMIKQMAASGDIRGLHFCTLNLEKSVVRILENLGWAGGS
LKLANKLIADTAIGPTERVITPHHAADSAAVSLAVAGPQPEGEAGKGELNNAASWDDFPN
GRFGDYKSPAYGETDLWGSSILSRNQALEQWGHPRTLDDLTTMFLGHLHSKIATTPFSPA
PLSPESIMIIEHLERLTRRGWWTVGSQPAINGVSSADEVVGWGPRGGYVYQKCFVECFIE
QKDLEKIERKVKEKGEGWIDLYAANLRGEFRTTAMEEARNAVTWGIFPGQEVAQTTIIEE
ESFLSWKDEAFAIWEEWASFYPPDSEERRLLNGVRNDRWLLTLIDHNYTNPSALWSFLFK
DDPVI
>E6KL60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis ATCC 49296|TrEMBL
MTMSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLA
DFIQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYA
TDLIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERF
YDFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLR
AAGLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A0D6PLL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidocella aminolytica 101 = DSM 11237|TrEMBL
MLSTPARPQPQTDLNEMHEEMTAAMQWNCLDGWSMEATARDIPNLAAMASRFAPGTIIAI
PYLASESDADRLDAAAAIRELGFTPMPHIAARRLSSCGALERLLEGWAARAKVERMLVLA
GDCARPAGPFEDALALLQTGLLRRHGVHTAVISGYPEGHPKIPDPRLARAMRDKLAAIAD
QGLTAEIATQFCFSATPLLDWLEELRAGGILVPVRLGVPGPANLRTLLRYAALCGVSASA
AVLARYGFSLTKLRSHAGPDQLVHALVSGLALERHGQVFAHFYPYGGMSSLGAWLERQRF
VHAPLVKVRIS
>A0A401G2R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfonema ishimotonii|TrEMBL
MRVTNLYENKKPVISMEFFPPRNEAAEKTFGATIDNLSTLQPDYMSITFGAGGSDRDGSY
QAVNQVMVEKKHPTVAYLAGYGLGPDEITEILDRYKALGVETIFVIRGDKPRGDDFSPHP
DSFPYASDIIAFIKDRYDFTLGCAGYPEGHIDAESLEKDIEYLKLKVDNGAEYVVAQYFY
DNAFFFEYVRKCRAMGINVPIIPGIMPVYTVKMTQMLSKVCGSSIPADLQGRLDAVDAED
KEAVLNLGIDFAAEQCRGLLKEGVDGLHFYTMDRSRSTTDILSRLKDENLL
>A0A1T5G923|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. 49Tsu3.1M3|TrEMBL
MSPPSLIDTHPNLAGAAPVALSYELFPPRSPAAAESLWTTIGELEATDPDYVSVTYGSNG
SNRSTAVDLVNRLVQETTLRPLAHLTCVGNSPQELAEIIGELLDVGVRGILALRGDRPKD
GEIPPPGSLRYAQDLIELIRRVEQRRSALLCAGRVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLLARARRAGVTIPIIPGVMPLTSLRRLARLGELTGVE
PAPELIERLAAADTDADRTRIGVSATVDLANAALDAGAPGIHLYTFNEHAAALDVLDKLA
LPRPRSGNKNSGNRQSGNRHGAGRINASRSAASGQLAS
>A0A1H8ZKV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium NE2001|TrEMBL
MKISEIYKKKKSLSFEIYPPKKDAELENIDETLDVLCELKPDFISVTFGAGGSSNNNRTI
ELAKKIKYQYGVEPVVHLTCLHYDKQEIEEFARVLEAEGIENVLALRGDRNDRVEEKNVF
KHSSDLITYMKQSHDFCFLGACYPEIHPESESRVTDIKDLKTKVDAGAEVLISQLFFDNS
SFFRFKEDCSLADINIPIIPGVMPVINAAQIRRMVSICNAAFPERFQKIINRYENNRDAL
FDAGMSYALSQIIDLLVSDIQGIHLYTMNNPVVARRICEGIRNII
>A0A3E2CU07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium NR017|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VSYIRSKRPDLPILGACYPEKHPEAE
>A0A3G2L3M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euzebyella marina|TrEMBL
MKITDHIKNAKGETLFSFEIVPPVKGRNIQELYNNIDPLMEFKPPFIDVTTSREEFVYRE
KDGLLEKQVTRMRPGTVGICASLQHKYGVDTVPHVLCGGFTKEETEYLLVDCQYLGIENL
MALRGDARKDQQYFEATKGGHAYATDLVGQIKDLNSGKYLHDDCQMDHLPDFCIGVAGYP
EKHLEAPSLKSDLKRLKEKVDAGAHYVVTQMFFDNQKYFEFVEAAKAMGINVPIIPGIKP
IAVKRHLQVLPQVFRIDLPQDLIDAVDDCATNKDVRQVGIEWAIQQSKELKEAGVPVLHY
YSMGKSDNIKAIAKELF
>A0A2M6Y8F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG08_land_8_20_14_0_20_45_12|TrEMBL
MKTKSNLERVLESKNFAATGELGPPQSADPEVIRRKARILKDHVDAFNVTDGQTAVVRMS
SWAACLIGKEQGLEPIVQMTCRDRNRIALQMDVLGVAALGINNILCLTGDHQKFGNHPTA
KGVYDIDSIQFVKMVKDMRDEKKFQCGEEMPVEPRLFIGAAANPFADPFEFRVIRLAKKV
AAGADFIQTQIVYNVDKFAEWMKMVCDKGLHEKVKILAGVAPIKSVGAARYMKTKVPGMD
VPDSVIERLRGVTKEQVPKEGIKLCVDIINQVRQIEGVAGIHLMAIEWEEAVPEIMEAAG
LLPRP
>A0A2A6JRB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. J15|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWETVSKLQDWDPDFVSVTYGAGGTTKAPTL
STVTRFLGQTPLATASHLTCVGATKEETHQVIDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGANRALTQF
FFDNDNFERYLERVRAAGVSIPIVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGYDD
KPEERAKVAAEVAAEQIEDLVRRGIDEFHLYTMNRAPLVSAVLDNLGFSRRPAKSAGAAA
>A0A6L9HG52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MQLKDYLKQGRLVADGAMGTYFEAKYPEEKGMAEACNLSCPDKIKAIHLEYIKSGARLIR
TNTFAANTMFFDTLDTVTQVVKAGWQIAEDAVKEAGQEVFIAADIGPVYDPQFLGKEQVL
KEYFAVCDTFLACGAQIFVLETQAEFAYVKEVAAYLKHKKDVFVGAFFSVDKNGYTRNGV
SMDKLIRQAVEAQELDAYGFNCGVGAAHLKRLLEGASFPGKKPLAALPNAGYPVELRGKT
IYQENKGYFVEMMRGIAALGVDILGGCCGTAPEYIFDMQKELKSVPVYPKKMAAAGQKPG
KAPYIMSPKKQWGSQKQILVELDPPFGIDISKVLHGAAELKEAGADMLTLADSPMARVRM
DAAKLAAHVQRKVGIPVMPHICCRDKNVIAMRSGILGDYMNGIRHFLVVTGDPVGRDDRG
VITPVFDFNSIRFMGYLAEMNADVFVENPVCYGGALNYHGANVDAIIRRMKQKMENGCSM
FLTQPVYSKEDMERVAYLKEQSGAAVLCGILPLVSYKNAVFLANEMPGIRIPEEVIARYS
PDMGRDEAERTGISLAVELAEKMQDAVDGYYFMTPFNRAGMMSQIVRKVKSFFV
>A0A3D3RLK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MDIREYLQNNILLMDGAMETYFDVLEDKKESIAERANEMDPNLIKRIHRSYIEKGAMLIR
TNTFAVNHVFFPKREEMRKCIHLAYEIATEAVEESQKDIWIGASIGPIPEDGELEDREQL
LKEYEFICDSFLEMGCKIFIFETFTVWEDVVKIAQYLKEKDENLFIMGHFHFNKMGYTKE
GLSIQRFVNLVGCQKELDAYGFNCGIGASHLYQLLEKVTFPSNKYLSCIPNSGYPYRMRG
KKIYSDSPLYFAEQMEKVVTLGANIIGACCGSRPSYIEKLKERIDLHRVYEKKIKKGREE
EIVFSNDQQNPFLAKLNRGKKVIAVELDPPFNQDAKKLLKGAELLAGEEVDILTLADSPL
ARARADSIQMAIRIQNETGITVMPHICCRDKNRIAMRSQVIGAHINGIRNLLVITGDPID
RGEEDRIKMVYNFNSIRLMDYIKDMNVELFQEEPMVYGGALNYSGANVKAIIERMEKKIE
AGCSYFLTQPVYSKEDMERIRYIKEKVNTKILCGIMPLVSYKNARFIRNEMPGIHVPDEI
FEQYHEEMTREESEEIAVNISVDIALKMKDIADGYYFMTPFNRVNLIARILKKLREELGE
>A0A838UD59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacteraceae bacterium|TrEMBL
MASLNALGPVARAGAREHRHRKVSFEFSPPKSPAAEESLWLAIRRLEPLNPEFVSVTYGA
GGTTRERTHRTVLRVLEETGLAPAAHLTCVGASRAEVDAVIADYWNAGIRHIVALRGDPP
GRIGGAYPARPDGYANATDLTRAIVAIAPFEVSVGLYPQVHPESPSVSHDIDVLKAKIDA
GATRAITQFFFDVDGFLRFIEQVRKAGISIPISAGIMPVTNFRGLGRMAAPCGIALPAWL
GNLFDGLDDDPETRRLIAAAVAAETCARLEEEGFDDFHFYTLNRADLVYAICRVLGVREA
AP
>A0A0D2JSU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fonsecaea multimorphosa CBS 102226|TrEMBL
MHVSKKLELAHQQNKPTFSFEFFPPKTAQGVQNLYDRMDRMHNLGPTFIDITWGAGGRHS
QLTSEMVNATQNYYGLETCMHLTCTDMERHQVDEALRRAYKAGCTNILALRGDPPRDQEK
WEAKEGGFRYAKDLVKYIKARYSDHFDIGVAGYPEGCDDHRDVDLLIDHLREKVDAGASF
IVTQMFYDVDIFLDWVKKCRDRGISVPILPGIMPIQTYAAFLRRANWTKCHIPPGWFEAL
EPVKNDDAAVRAIGKDLVADMCRKILDSGIQHLHFYTMNLAQATRMVLEELSLTPETSGM
PLEKPLPWRQSLGFNRRDETVRPIFWRNRNASYISRTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNDANIKLWGKPRSLRDVTGLFVRFLQGDLDRLPWSEGGISAEADIIKDDLL
QLNKHGFLTINSQPAVDGASSTHPVYGWGPAGGWVYQKAYLELLVFPSMFETVMERLNAD
KNLTYYAVNRKGELYTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WAKCYPAGSGSRKLIEKIMDECYLVNIVNNDFHQNKEIFKVFEGLETKDLDLVLEDTAPS
HLENGAKDVSNGDAPPAGVGKGLTNGDQHKVPSKASGEVVLN
>A0A330HSG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cereibacter johrii|TrEMBL
MARPRISFEFFPPQTLEASFRLWETAQMLAPLKPDFVSVTYGAGGTTRKLTHEAVETIHN
HYRLNVAAHLTCVDATKAETLEIAASYAEAGVTEIVALRGDAPKGADRFTPHAEGFASSV
ELVEALAATGRFKLRVGAYPEPHPDAADTLADVRWLKRKIEAGATSAITQFFFEAETFLR
FRDLCAKEGITAPIIPGILPIENWSGVKKFAARCGAQVPGWLDDAFDHAKRDGREELFSV
ALCTELCDRLLSEGVEDLHFYTLNRPTLTREVCHALGILPEVALQNVA
>A0A179YJ03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus rhamnosus|TrEMBL
MKISQCFKDHQVISFEVFPPRKNATNIAMRPILNTLDAVKAADPDFVSVTFGASGNKPHM
GTLEVAKLIKNEFNLEPVAHLPAAQLTRAQVDAELRGFQEAGIDNILALRGDIPKSGRVS
EDFPYACNLIEHIHQVGDFDVVGACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYRFRERAALAGINVPIEAGIMPVINEHQIERMATMAGVHLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A1F3Q9G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium RIFCSPLOWO2_12_FULL_35_15|TrEMBL
MKVTDHIKQSKSTLFSIEILPPLKGKSIQSIFDGIDPLMEFKPSFVDVTYHREEYLYKKR
DGGYLEKVSIRKRPGTVGICAAIMNKYHVDAVPHIICGGFSKEETENALIDLHFLGIDNV
LALRGDSIKSEPEFVPEPNGHAYAIDLVKQIGSMNKGHYMEDELADVAPTNFCIGVAGYP
EKHFEAPNLISDMKHLKTKIDAGSEYIVTQMFFDNIKYFEFLNKCKDMNITVPVIPGLKI
LTTKKQVNILAKIFKIDIPQPLLEQIEKCKTDAEVKEVGIEWCINQSKELIKAKVPCLHY
YTMGTSEATRRVASQVY
>A0A258RW60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. 28-63-12|TrEMBL
MTISIPQLEEARRALEAPLFADLAGDANVSFEFFPPKTEKMEEALWETVKTLEPFGPRFV
SVTYGAGGTTRERTHATVARIQRETSMGAAAHLTCVEASRDEIDAIADAYWLAGVRHIVA
LRGDAPAGKSFAPHPNGYTNAADLVAGLKRLHPFELSVAAYPECHPDSRDQADDLDNLKR
KLDAGATRGITQFFFEPETFFRFRDRAAAAGIDAEMVPGIMPVTNFASILKMSAMCGTEV
PAWLGRLFEGLDDHPTSRQLIAATLAAELCRKLYAGGVRDLHFYTLNRAELSFAICHLLG
LRAKAGERAEAA
>A0A2M9JA37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB01201|TrEMBL
MALGTASTRTDRARTVRDMLATGETTYSFEFYAPKTEKGERNLWNALRRVEAVAPDFVSV
TYGAGGTTRTGTVEATQQIAEDTTLTPVAHLTAVGHSVAELRHTVGQYADAGIRNILAVR
GDPKGDPMGEWVKHPEGVTYAAELVSLIRESGDFCVGVAAFPEMHPRSADWDSDIRNFVD
KCRAGADYAITQMFFEPENYSRLRDRVAAAGCETPIIPEVLPVTSVKQLGRLPQLSNAVF
PAELRDRMLAAKDDPAAVRSMGIEFATEFCSRLLADGVPGLHFITLNNSTATLEIYENLG
LHQQA
>A0A2T0PZN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allonocardiopsis opalescens|TrEMBL
MLAEPRGSARPHHRRHIRELLAEGRPTFSFEFFPPKSDDGERVLWRSIRDLEALRPSFIS
VTYGAGGGTRDRTVDTTERIATDTTLLPVAHLTAVNHSVRELRHLAGRFASVGVCNVLAV
RGDPPGDPQGEWVRHPEGVDYAEELVRLLRGSGDFCVGVAAFPYKHPRSPDIASDTEHFV
RKCRAGADYAITQMFFDADDYLRLRDRVAAAGCEVPILAGVMPVTRFGTIERSVQLSGAP
FPPALAAQFEAVADDPAAVREIGMDQATRMCQRLLDEGVPGIHFITMNRSTATREIYQRL
SAPEPASGSRAPITA
>W9WQ19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cladophialophora yegresii CBS 114405|TrEMBL
MASAHDDRLPTLFSSLDPSSYYFSLEFFPPKTSSGFSNLQSRLARMATALRPLFVTVTWG
AGGSTATKSLELAELCQRQLGLTTVLHLTCTNMKKDMVDEALEAAKEIGIRNILALRGDP
PREEYRDATSTGETEGGSGGAGTGSNEEFTWAIDLVRYIRRKHGDYFAVGVAGYPEGHAD
ESHPEQGKQSVEHDLPYLVDKVSAGADFIMTQLTYDIEAYRRYEDRLRNYADQEGRRVFD
KIPIIPGLMPIQSYQIIKRITKLSHAKLPEDISRRIEAVKSDDEAVKKVGVEVLGELVEQ
MKTLPQPNGVPRGFHFYTLNLEKSVAFILERTGLIPPVSSEGSTEDRDGDSSSDPDAVVD
DDKPNGAVTFTNRQADQDAHQAPVSAFSKRRRSSVNAQPHNRVILDRSSRSPAQARPDGD
TDPPNGRSSSLTAQHSARDRGTGIPASSPTRRHNLLISEGQGSLGREATWDDYPNGRFGP
SHSPAFGEIDGYGPSLKVSPLVARKLWGHPKSPKDVTEIFRQHVSGELAGVPWSDDIDPS
GNDGITSSSKDMTAGALRAETDVIRSALLSLISKQNYWTLASQPAVDGAHSSHPIFGWGP
PGEGFVFQKAFVEFFCSRDEWESRLKNRLQTYGSEVLSWMKTDVKGAFESAQHAQHAALP
TNGATKATNPISTMDINARAGASSEMDTVNAVTWGVFPSREILTPTIIEAESFRAWAQEA
YAIWSEWKRCFPRGSEEAAFLDRARGDVVLVNIVGQEFRGGHEGQGGRLWKILLGEDGEN
HN
>A0A127CIM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Martelella sp. AD-3|TrEMBL
MSESTETRGRKRAIDFSFEFFPPKTAEAEAGWWRSVEELAAYEPGFVSVTYGAGATSQAP
TYAAVKRLVDETRLQTASHLTVVKAGKGEVDDVIRRFRDAGIRRFVALRGDPPGGIGTAY
SPHPGGYANAAALVSALKAIDDFDISVSAYPEKHPESADRAADVAMLKAKAENGADRALT
QFFFDNDVFEDYLNDVRRAGIVIPVVPGIMPIQNLAQLKRFAAMCGASVPAFVERRFEGL
DDDPDGRFEAAADLAAEQVQDLVARGIADFHFYTMNKSKLMTAVLDRLGIKPGDTLSDAV
PERMRA
>A0A016ACT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis str. S36L11|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A1Q9J144|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. 831b|TrEMBL
MKISEKYKEKQGEGRLPKKSLSFEIFPPKKDSELKNIDETLAVLCELEPDYISVTFGAGG
SANCNRTIELAKKIKYEYHVEPVVHLTCLHYDKKEIDEFAKILTDVGLQNILALRGDRNP
NIPEKGDFRHASDLISYMKEKGDFCFLGACYPECHPESDDRVSEIKHLKAKVDAGAEVLL
SQLFFDNKVFFRFQEDCRIADIGTPIIPGIMPVINAAQIKRMITMCGATFPTRFQKIISK
YEENKEALFDAGMSYALSQIIDLLASDIDGIHLYTMNNPLVARRICEGIRNII
>A0A022W6G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton rubrum CBS 288.86|TrEMBL
MHIKDKLALAEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMPRERVDDALQSAFKAGCTNILALRGDPPREKEA
WEQTEGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFLDWVKKCRQAGIKVPIIPGIMPISTYAAFIRRTNWVKCAVPKGWMEAL
EPVKNDDAAVKQIGKALVSEMCRKLLENGINHLHFYTMNLAQSTTMVLEELNLKPSTETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSVRDLSDIFVRFLEHKLDRLPWSESAITQESEIIKDDLID
LNNRGFLTINSQPAINGAKSSHPIYGWGPRNGYVYQKAYLELLISPALIDEVVRRIESNA
DLTYHCINKDGELKTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSASRKLIQNTMDTWYLVNIGKAPSIPFVYFLTSMLTNCFSE
>A0A7U3Z6T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. AS13|TrEMBL
MSFFHANQREALNQSLAELSGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLDAAPHLTCIDASPAQLREIATDYWNNGIRHIVALRGD
LPPGGGKPDMYATDLVRLLKEVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAA
>A0A3B3E1Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzias melastigma|TrEMBL
MVNQRLEGGWQTCRSDSSGGSNSSGESSKDSSRCSTPLPDGDRTDRLRDKMRRRTESGDR
WFSLEFFPPRTGSGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVN
YCGLESVLHLTCCNQTREKITGYLAKAKHLGLKNIMALRGDPIGTDWEEEEEGFNFAVDL
VKHIRSEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTFLK
FLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEDITKVIEPIKDNDAAIRNYG
IHLAVEMCSVLLESGNVPGLHFYTLNREVATMEVLRQLGLWLEDPRRPLPWAVSANPKRK
VEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALL
QMWGEELKNEQSVFEVFTSYITAQPNQSGHKVMCLPWNDDPLAPETNLLKDQLEKVNRRG
VLTINSQPNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSSENVAALLKVLKKYEPRVNY
HIVNVHDQNLNNAADMRPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKL
YEDESPSRMIIQYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPEPLHSETV
>A0A812BLG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sepia pharaonis|TrEMBL
MNIFVPLIEQMKAQIASKDPWFSLEFFPPKTMEGAYDLFQRMKILAQGQPLFCDVTWHPS
NQPGNMEKPTSSMCVASTMLNYLNIQTMLHVTCCHQPKQNIKEHLITAKKQGIRNILALR
GDSLPGQEWNPKDNDLTHAKDFVKFIKDEHEDHFVIAVAGYPVGHPECPSYEDDLRYLKE
KVDAGADFVISQLFFDVKTFINFVADCRKFKITCPIIPGILPIQSYDSLRHISKLAKLEV
PKNIVDTIQPIKDNDEAIRNFGIFQAVEMCRALLNSDHAPGLHFYTLNRDYATNSILKQL
GLLTADIQRTLPWKPSANYARMDEEIRPIFWNLRPQSYIYRTSNWDNFPNGRWGNSSLAS
FGNLTDYYMFYLNQPPKTELLKMWGTRLEEEQDVWNVFKLYITGETNENGIKVSMIPWHD
DALSPETSLIAKELASLNSQGVLTINSQPAINGLPSSDPVFGWGNPNGYVYQKAYLEFFV
SKEKAEILNKILLKYPQVNYNIVNSQGDINYSNCDETQPIAVTWGVFPGQEILQPTVVDP
IAFNIWKQEAFDLWKTNWGNLYPPKSESQNIINYFHDNYLLVNLVDNEFTKPTCLWTITA
KMLAGEKN
>R6UPQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium CAG:64|TrEMBL
MIENYLNTQGYMLFDGAFGTYYAQRYAEDQKPCEMANLNHPKRVAAIHQEYIEAGADAIK
TNTFSANEQHLECSWEMIRRILQEGYRIAKKAAKDKVKVFADIGPIMEQKNVSLAQQYQR
IADVFLAEGADCFLFETLLNTQELHAVTSYIKEQCPQACIIVSFAVTADGYSRQGIAMSR
LLQDCLADEHVDACGLNCVCGPMHMKRLLDSIDRTQKPILIMPNAGYPTILANRTYFRDS
STYFAKEMREIWQKGARLLGGCCGTTPVYIQKTREALQEHKIIQKVQQPAQETERIPQED
HNPLRRKLQRKQPVIAVEFDPPANCEIERFMNHVEFLKEAGVDAVTIADCPIARARVDSS
LIACKLHRELGLDVIPHMTCRDRNINATKALLFGLQIEGIRNVLVVTGDPIPSEDRQEVK
GVFNFNSQILAGYIRDLNETMFTSPFMVFGALNLNAVNFEAELAKAKRKVTQGMEGFLTQ
PVHSRQALFNLKRARKELQAYILGGVLPIVSHRNAVYMNNEISGIEVDEEIVAMYEGTTR
KEAQKLAVDISCKTMDEMRPYIDGYYLITPFNRVEIIADMITYIHKQ
>A0A727TIN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. houtenae serovar 48:g,z51:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A136LJF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium OLB15|TrEMBL
MMTHLSFKTRLTQPAPILADGGMGTLLSDNGVPMEATNDSLNLSQPETVKALHRAYLEAG
AELIETNTFGANRYKLMEHGLEDRAQAINVAGAKIAREAVAESGGTAYVAGSIGPLGAGL
QPYGRIKPEDASAAFSEQITGLLAGGVDVLIFETFTDLAELRVAIDAAHKTAPALPIIAQ
MTFGRDDRTIYGYLPGRVARELNEAGVDVIGVNCSGGPAQITRVLIAMQDAVPDAKLSAM
PNAGYPQNVGGRMIYTASADYFGSYARTFRGLGAAVIGGCCGTTPAHIAALRRSLDLPEA
EGERITITRQREDDERAAQAPDRPSELSHRLATGQFVISVEMNPPRGHNFERLLNAARTL
VDAGATVLNITDSPTARMRSSPWAACHAIEQAVSIETILHFPTRGRNMLRVQGDLLGAHA
LGLRNIFVCMGDPTRIGDYPAAMDNYDIVPSGLIKLAKQRLNEGIDQAGNSIGQPTSFTI
GCALNMVADDLDKEIDVLRKKIANGADFALAQAVFDPAKAERFLRRYEQVEGHPLELPVL
IGILPLYSLRHARFLNNEVPGIEIPEAIFKRIETAGEGAAQEGVRIAQELLRDLKDLARG
AYIIPSFGHYDLAAQVVDAVGVAR
>S3AEM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. oral taxon 186 str. F0373|TrEMBL
MSVATATPAAAASRIAGCPKSMAYGPCGGVNADGTCEVHPTPCVFLARDLPVRWTSPATG
ETPPDAVSEDPSRPATTAGRELVEIAVRRPLVFTGFPVRALRADAVGPTAEALAGSVDAV
LSGDAGRSRVQFPPSYRAALIGATGLRVWMGFNARDRNRTALERELLSLRVLGVAGVHCV
TGDHTQTGDRPDARPVFDLESTTTLPRAASLGLLTSFAESPAAPPVAERGARVAEKQRAG
GRMCLTQYAGDAEEVAAFVALCRAAGADVPVLAGVPLVVDREGAELLASFHAAKLPSGFI
DRLFAARDVRAEGIRLAVAYGRALLATGAVGGVVIAGGARSGGEAAYAADLATVARELGG
GS
>A0A525JDB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp|TrEMBL
MTEITPAPQDRHAGQKLPAISFEFFPPKTEEMERSLWETIKRLAPLEPSFVSVTYGAGGS
TRERTHSTITRILSETSLLPAAHLTCVGASRGEIDDIVGRYYDAGVRHIVALRGDPSGGI
GTAYTTHPDGYRTSADLVAGIKRQHGDIEVSVSAYPEKHPESRDFDADIDMLKAKVDAGA
ARAITQVFFDNDLYFRYLDRVRARGIEIPIVPGIMPMHNFKQARAFVTRAGTTVPNWLAE
KFEGLDDDPETRKLVAATVAAGQVQKLAKHGIDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A077FHG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas alkylphenolica|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKEDLRSLLSQYKAAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHIEIAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVNSIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A5M3MJY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coniophora puteana (strain RWD-64-598)|TrEMBL
MKISQKVQHSQSQGKVWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFVDITWNAGGRTS
ELTSELVKTCQGTLGIETCMHLTCTNMPMEKVDIALREAKEHGCRNILALRGDPPAGKEE
WEAVEGGFVHGIDLVKHIRKNYGDYFDIAIAGFPQYHLLPPEERDAEMRYLKEKVDAGVN
FIMTQMFYDVDLFIDWVKAVRAAGITIPIVPGVAPVQTWNGFLKSTNLAKTQIPQSFMDV
LEPHKNNDEKVREIGTKLVAEMCRKILAADIGIRGIHFYTMNLEKATKMLLEELNLVPRV
ETVKPLPWRQSLTPSRRNETIRPIFWANRAKSYLSRTENWDEFPNGRFGDSRSPAYGELD
GYGVSLKHSVKEGLKLWGEPSTFGDVTKLFSRFCYKELNALPWSDQAAATETSIISNQLA
RINELGFLTINSQPAVNGARSDDPDVGWGPSNGYVYQKAYLEFFVGPKLLDLLISHIEQD
INITYYVINRQGDLRTNNHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGMK
WADIYQKDSQAHKTITGIMGTSYLVNVVHNDFKDPEAIFQPFFKAGEEYAKSHADGSPVH
DGVPN
>A0A0E0KKM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryza punctata|TrEMBL
MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLK
RKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNL
GLIEESKVSRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLD
QLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWSKGWACLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAFKEI
>A0A383UNR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blumeria hordei|TrEMBL
MEKISNKIKALPPGQNYFSLEFFPPKTSTGTANLRARLERMSRALCPLFVTVTWGAGGAT
ASKSLDLAAMCQRDLGLTTCLHLTCTNVTQEFVDGVLERAYNLGIRNILALRGDPPRQEF
IKNHSDTKDTVEFEWAIDLVSYIKAKYGDYFCIGVAAYPEGHADRENPDEQNLMHDLPYL
VDKVNAGADFIMTQLFFDVKAYDHFEKVLREHDSGCFKDLPIIPGIMPIQSYQTIKRTIK
LAHARIPPEFMARLDSVRSDDALVKQRGVDIVSEIVTHIKHTPSSAPGTRGFHFYTLNLE
KAVALILQRTSLIPSSQAIDELESNRNANSNECEANTNGTCPQDTRQATNSVDPDLFNRV
VITESKPSDPQIEATIFEASALSKPDYSRAATLAIIEGEGSLGRDATRDDFVNGRWGDSQ
SPAYGMIDGSCVILHMSRKQAIELWGYPSSIEEVTSIFLRHIEGSISAIPWSEDDLCHES
EAIKVPLRALNRKGWWTVASQPPVNGISSQHPIFGWGPPRGFVFQKAFIEFFLPSAAWSA
LRAKLESSSIAPDVSWYACNAHNVFKSSNPTINTSSEMGRTSRCTNAVAWGVFPGREIIT
PTIIEEVSLRSWAEEAFSIWSEWARICAESGSKSGKMSREFLEGVYEDLWLVNIIHHDYF
KEDALWDILLE
>A0A2M8B7T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_9_14_3_um_filter_63_12|TrEMBL
MNSEPNLTAVTRRDPSQRLGFHEALETGEFVVTAELMPPKGPDVESFKEKIDVLSGRVNA
INVTDCSRAVLRMSSMAASVIIQQRGVDAVYQLTCRDRNILALQSDLLGAAALNVRSVLA
LTGDGIRHGDHPDAKPVFEVESIGLLDIIRKLNRGKNSAGGTLNAPARILAGAVVNPNFL
PGRSHRKRFLKKVEAGARFFQTQMLTNMEAFESFMEYARPLGATVLGGILVIKSLKNAQF
LNEMVPGIRIEEEILKRFEANDSLDTGLDIAAEQVARCRELCGGVHIMSLGKEQLVLDVL
DRAGL
>A0A1Y5T3T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falsiruegeria litorea R37|TrEMBL
MTAPDISFEFFPPQNLEASFRLWDTVQTLAPMDPRFVSVTYGAGGTTRDLTREAVATLHK
SSGLNVAAHLTCVNATRAETLAIADQFAEAGVTDIVALRGDPPKGEGKFTPHPDGFANSV
ALIEALAATGKFTIRVGAYPDIHPEAAHAQADIDWLKRKLDAGADEALTQFFFEAETFFR
FRDACAKAGIEKQITPGILPIENWKGARNFARRCGTTIPQWVEEAFAKAVRDDREDLLAT
AICTELCSDLIEGGVDKLHFYTLNRPELTRDVCHALGVVPKADLQNVA
>A0A2D9ARM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVIEXIKNXNKTLFSFEILPPLKGESIXSLYKSLDPLMEFXPPFIDVTYHREEYVYKXK
DNGLLERRSVKKRPGTVGICAAXMNKYNVDTVPHIICGGFXREETENALIDLNFLGIDNL
LVLRGDPIKSEIYFSAENDGHSYASELLMQVSDMNKGIYLDNDLRXTVSTDFCIGVAGYP
EKHFESPNMFSDIHFLKKKVEAGAEYIVTQMFFDNQKYFDFVKLCRENDIHIPIIPGLKP
IATKKXLTLLPQRFHLNIPSELVNLIIKSKNNDEVRNIGIEWAINQTRELIEFGVPXIHF
YTMGKSDNIQKIVQKFI
>A0A1F3X0N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RBG_16_58_11|TrEMBL
MSDKRTFSFEFFPPKTPEGMEKLRATRQQLAQLKPKFFSVTYGAGGSTRDRTLEAVMEIQ
ASGSASAPHLSCIGSTQESIQEILDLFKAKGIRHIVALRGDLPSGMADPGEFRYANELVA
FIRKQTGDWFHIEVAAYPEFHPQAKNAQDDLANFKRKADAGASSAITQYFYNADAYFRFV
DDCVAMNVTIPIVPGIMPITNCAQLSRFSDACGAEIPRWIRKRLEAYGEDLDSIRAFGLD
VVTDLCDRLLQGGAPGLHFYTLNQAGPSSTIWQRLGL
>A0A498LZK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labeo rohita|TrEMBL
MVNQRADMGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITGHLHKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIVTQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIKQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRGNSSSPAFGELTDYY
LFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITGQTNHNGHKVMCLPWNDDPLAPET
NLLKDELEKVNRRGILTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTA
LLQVLKKYEPRVNYHIVNVQGRNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWK
DEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLDSCLWQHYSLVQFAF
>A0A829LYH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus MAB_091912_2446|TrEMBL
MAGAARVFERLRPVFRFRSPTVAGGSTRDRTVRVTGELAENTTLLPVPRT
>A0A383UP84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blumeria hordei|TrEMBL
MHIKDKLRQAESSGHPTFSFEFFPPKTTQGVQNLYDRMDRMHGLGPSFIDITWGAGGNIA
QLTVEMVSVAQSQYGLETCMHLTCTDMGLEKVDKALKDAYKAGCTNILALRGDPPREQEK
WTATDGGFHYAKDLVKHIRATYGDHFDIGVAGYPEGCDDQDDPELLLDHLKEKVEAGGTF
IVTQMFYDVENFLEWVGKVRAKGINVPIIPGIMPINTYASFLRRCNHMGCKIPPKWATAL
EGIKNDDAAVRSIGTGLVAEMCRKILASGLIHHLHFYTMNLAQATRMVLDQLGLTPSEER
PLKQALPWRQSLSLGRRDEDVRPIFWKNRNKSYVTRTQDWDEFPNGRWGDSRSPAFGELD
AYGIGLKGSNQQNRKLWGEPECIKDVAEIFVKYLDGKIESLPWSEAPISSEANKIKKELE
DLNRRGFLTINSQPAINGIKSSDSTYGWGPPNGYVYQKAYLELLVPAYLIDELLTRVSKD
AYLTYYAVNKAGDLKTNSTHEGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGID
WAQCHSATSPSRRLIEKIMDTWYLVNIVNNDIFENNKLFELFEGLQVNDIDKPLESPKIM
NGNSAHQNGHEPYENGKVTIENGNH
>Q1K3H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas acetoxidans (strain DSM 684 / 11070)|TrEMBL
MSTPPFMQRIQETVLIGDGAMGTQLYSRGVPADSCFERLNLTRPELVTSVHEAYVKAGAQ
LLETNTFTANGVRLGGVGLDGQVRQINEAGARLARKAIGSGRECFVAGSVGPLGSRDSEE
THSVDDQKSLFREQMTGLVNGGVDLLLLETFASLAELQLAASVAVEFGLPVIAQMAFFAE
GRTREGLDGGQFVAALKSDVDVVGANCGVGPHEMLQLVRQMVAATSGPVSAFANSGFPQY
VNGRHVYLATPDYFAARGLEMVEAGAGLVGGCCGTTPEHIAALTAQIQGVKPSRVAVPHP
VERRKPVAVEVGESRQTTVSPLLDPARKTVPITVELDPPRGLDCSLTIERAKLLAQNGVD
AINLAENPLARIRMGNLALAAKIQDATGIPVIAHVTCRDRNLIGLHSDLMGAHLLGLRHI
LAVTGDPVSVGETSGATSVFDLNSVGLLDLLSHLNQGRNMLGADLGEGTGFCLGAAFNPN
VTHLQGQVNKLKKKLAAGAQFFQTQPVYSSTVFQDMVQALQDVSAPVFLGLLPLVSERNA
EFLHNEVPGITLPDEVRKRMRGTVGDSGVVAGMGIASELVRSCAPQADGYYIMPPFGKVD
LALQLIEIIKATSA
>N8QSZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASIS
YPDSIDKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKAFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYVEQYRHLELKALEELWNSLWQVT
KGKEFSPEIARFSRQPTSKQIIKYRQLHVMHEAMFGSKIAKGIGRFIFKASFWENTLVAK
VLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKEKLIPTVPLEIRGTSSWKNWYLGVEA
>M9YGJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azotobacter vinelandii CA6|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARRLAGCDPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSRAELRSLLNTYKDAGIRRIVALRGDLPSGMGLANGELRHASDL
VEFIRAETGGHFHIEVAAYPEMHPQARNLEDDLARFAAKMKAGADSAITQYFFNADSYFH
FVERVRKLGVEQPIVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFG
EQVVTAMCEKLLEGGAPGLHFYTLNQAEPSLAIWNNLGLPR
>A0A3D4W267|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp|TrEMBL
MKDIRELLQTRPLLFDGAMGTYYKAAPGVECEQANLTDPAGVLAVHREYLAAGADAVKTN
TFSLPRLAAAHTPGWEQLAQAGWQLAVQAAGETGAAVFADLGPAPDTEAVPAGQVYTAVA
KQFAALGARNFLFETLSSDAGLLDAVGAIKAEVPDAFVLVSFAVLPDGYTREGMYCKDLA
RRMQESGIVDAVGLNCVSAPGAMRTLAKQLGGTLPLSVMPNAGYPVVTRTQVKYQGRPEY
FARELGRLAAEGTVQILGGCCGTTPAHIAALRAELDSLPVVEKTAPAEEFSTVKEQTVEN
EDAFLRKLNAGKKVIAIELDSPRNADLTGYLEGAKKLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGLCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPGPMTVFGALNLNARNFDVELRRAKEKLENGMSGFL
TQPVLSAQAVENLRKSRETLGADAKILAGIMPVVSQRNAIFMENEINGIHVEDWIIEKFA
GLDRAQGEELGLAISLEMAKAALPYADGLYLMTPFNRVALMERLIGRLKQEVLGAY
>A0A562GLK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa sp. KB1|TrEMBL
MMSPKCSFSEALADPEQLSITWELVPGRGMREKAQEHLLKMAELAAKDPKINAITITDNP
GGKAAILPYSMAVEAKRLGIDPLVHFTSKDKNRNALESELYALGRADIHNLLVMTGDYPT
EGYAGLAKPVFDFDAVHALRMITKMNEGAYTNLPATHFFAGAVVSPFKATEAETMAQYYK
LHKKIANGARFIITQLGFDARKFDELRKYADSNQFNVPLIGNIYVLSVPVAKLMNKNLIP
GCVVTDKLVKKLEAEQADAANKKEQQLLRAAKLYAVLKGLRYDGVNIGGHGLSYADVQYI
MEKGEEQSGNWQDIAVADFDYPQADGFYFFEKDVTTGLNTCQPFDRRQTGSGHSSLKQSV
MDLVHGVAFDHKAPLYPLNKAVAKFIDNSCLKKPFTIAEYTTKTMTNECRFCGDCAMHEL
GFICPMSQCPKQQRNGACGGSRDGWCEVYPEQQKCIYVKMYEGFKGGGKEERMKAKYMPP
CNWELHRTSSWLNYFNDRDYNNNKG
>A0A3N9UA72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus composti|TrEMBL
MGLLESLKTKVLTADGAMGTLLYSYGLDYCHEEMNVSKPEIIKKIHKEYIDAGADIIQTN
TYGANAIKLARYGHESRVAQFNKAAIQLAKEAVSQGGQFILGSIGGIRGVRKTDLTLDEI
LIAIREQVELLIEGELDGLLLETYYDFEELTETIKMIRTLTDMPIVAQVSMHEPGVLQNG
LSLNAALQELERLGADVVGVNCRLGPYHTIQAFEGVELPENSFMSAYPNASLLDIEEGRV
IYESEVDYFARAAVELRDQGVRLIGGCCGTTPKHIKEVKNRLSKLQPVEKKEAKLQEAIQ
IREPEPRNLEPLHEKVKRERSIIVELDTPRHLEIAAFVEGAKTLYDEGADIIMMADNSLA
SPRISNIAMGSILKLQYGIRTMPHITCRDRNLIGLQSHLMGLNALELHDILAVTGDPTKV
GDFPGATSVYDVSSMELISLIKQLNEGISFSGKTLRKKANFSVAGAFNPNVRVLDRAVSR
LEKKIEHGADYFISQPVYSKEKIKEIAEATKHLSAPIYIGIMPLTSFRSAEFLHHEVPGI
KLSDEVLERMKACEGDKAREAEEGVAIAKELLDTAAQHFNGIYLITPFLRYDMTVQLMQY
IKLLDEQNKGVNVNV
>A0A7M7IVR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nasonia vitripennis|TrEMBL
MEFIRGICYRRRGRRRDACRDTQICEPLFYALTWHEGWATGEERFPSLKSAEVFPRNTLL
HCTAKGLKKTDAEMILTRALELGIANIFALQGDSGSDDGDFDHASDLVKFIRERYGQQFS
ICVAGYPEMHPHSPSKELDIFYLKAKVDAGADFILTQFFFESQLFIKFVNDCREVGISVP
IIPGIYPFTDVKLLGKMIEICHTNIPDWIQEELRHIEDDDEAVRKFGIDLSVKLIKEIRE
SAHFCGYHVYTLNRSFSAIEVHRQLNTQHEIDQLVASNS
>A0A8J2UKB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalicibacterium flavum|TrEMBL
MTQQNFSIEFFPPKTPTGVEKLRATCARLGELNPRYFSVTFGAGGSTQHGTLDTVLDIRR
AGHDAAPHLSCLGSSRDSLRAILKEYQSHGIKRIVALRGDLPSGYGAMDMSSGEFRHANE
LVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDIANFVRKVKAGADSAITQYFYNPDAYF
RFVDEARKAGAEVPITAGIMPITNYTQLMRFSDMCGAEIPRWIRLQLASYGDDGDSIRAF
GLDVVTDLCERLLAGGAPGLHFYTLNQAAATHAIWSRLNLSQK
>A0A1B9GPM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kwoniella heveanensis BCC8398|TrEMBL
MKITEKLQKAEKEGRTFWSFEFFPPRTAQGLQNLYDRIERMRNLGPEFIDITWGAGGKNA
DLTNSLVQVCQETIGIETCMHLCCTEMPKEKVEWALQQAKAHGCQNILALRGDPVAGTST
WKPTPGGFMNAVDLVRHIHKYYPGDFCVAVAGFPQGHPETPEGHDAQEQEMKWLKEKVDT
GAEFIFTQMFYDTDIFFDWVKRVRAAGITVPIVPGIMPIQNWEKFEKWVQRENIVVPDHF
YEALRPVKGDDEKVRQVGTKLVAGMCKTILANKEAGIKGLHIYTLNLEKGARMLLQELGF
EGRREQIAPLPWRPSLTPHRRAESIRPIFWANRVQSYLSRTDDWDEFPNGRWGDSRSPAY
GDLDGYPVSININATDAYNLWGHPSTFTEVCDLFARFCRGDLAKLPWSSQPPASETSVID
EQLAKMNELGYLSINSQPAVDGVRSDDKVHGWGPAGGYVYQKAYLEFFVSPELLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWANLYPEASPSRKLITDIMNTSYLVNIVANDFRDGMSIFEPFLLDQQQQQQALSSV
GKVGQVLGDGIQTVVDGVKNAVVGNSNVVNGHTAQAHAEEDVKLTNGVVINGNGH
>A0A3D4VXQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp|TrEMBL
LGGCCGTTPAHIAALRAELDALPRQTEAAPAAKLSTVAAPEVEKDDTFLRKLDKGEKVIA
IELDSPRVADLSGYLDGARRLQAAGADLLTIADCPIAQARMDSSLVACRVHRELGMCALP
HMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVKNVYQFNSRKLAQYIVS
LAGEGREMPSPMTVFGALNLNARNFDVELRRAVEKLENGMAGFLTQPVLSAQAVENLRKA
RQTLGERAKILAGIMPVVSQRNAIFMENEINGIHVEEDIIQRFAGLDREQGEALGLEVSM
QMAREALPYADGFYLMTPFNRVALMERLIARLRTELLDAEG
>A0A1Z9XJP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. TMED35|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASKDELRQIAQDYWDSGIRRIVALRGDLP
PGMDNTEMYASDLVALLKEVADFDISVAAYPEKHPEARNAQFDLLNLKRKAEAGATEAIS
QFFFDTSVFLRFRDRAAAAGVDLDLVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRGDSK
>Q04NW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTQDGDLKLMGTVKELARLDPDFVTVTYGAGGSTRDK
TAQILSEISKNYSFPTVSHFTCVGANQDQIFKTLKEIRSSGIVNLMALRGDPPKGEGKFK
KTEGGFENATELISFIRSEKLDFCIGGGCYPEKHPNAKSLEEDVRNLKRKVDAGTDFLVS
QLFFVNSIFENFLNLVRKADIRAPVIPGIMPITSFSQIERFRSIAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSIKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A1I7CST4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. YR577|TrEMBL
MSNYGFSRRSDIGDKIRVSFEFFPPKTDEMEARLWDTVKRLEPLQPNFVSVTYGAGGSTR
ERTGRTIKRILGETSIPAAAHLTCVGASKDEVNAVIAEFVSYGIKRFVALRGDPASGVGG
TYRPHPEGYQNGADLVAGLKSFGDFDISVAAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFASRAGAHVPAWLAERFE
GLDRDPQTHALVAAAVAAEQVLDLVERGVGDFHFYTMNRSDLVVAICHMIGIRAPAVSVV
DTAGSAAA
>A0A1F7SJS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Schekmanbacteria bacterium RIFCSPLOWO2_12_FULL_38_15|TrEMBL
MQFSESIKRNDFLVTTHLESCCPDDAFDAIKTANFFSSFINGMLISDELQFNSKIGSIAI
CHLLKDSGIDPIVHIACSGKTKKLLEAFLMTSWMLGIKNLCITSEKVSIIKSKSETSETK
EVNALQLINFIHRLKEGKDFSNKNIREKPSFTVGTLLNLENGNSESCGETIKQKIEAGIE
FIITTPIYSIRQIENLIQYTEGKGVKIIAGVMPVLSVEAARRVNHSQHEKPITSEIIERL
GKAKNSIMEGIHIASELVKEIKNKVNGIHLVASEKIIPKVLKESSISQIPSLSLMKEEND
FQKLNQIFEGKLSIKELEKAYIIRVLKNNRGNRSAAAEVLGIHRNTLMRKCQEFEINI
>A0A6N9U443|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces halstedii|TrEMBL
MALGTPSTWTDHAPTVRELLATGKTSYSFEFWAPKTAKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTREGTVRATQQIAADSTLTPVAHLTAVDHSVAQLRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSDDWDSDIRHFVD
KCRAGADYAITQMFFHPESYLRMRDRVVAAGCDTPVIPEVMPITSIRQLERFAQLSNASL
PSSLKERLLAAKDDPAAVRSIGIEFATEFCAELVSEGVPGLHFITLNNSTATLEIYENLG
LHRQS
>W1YNI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|human gut metagenome|TrEMBL
VELDPPKSSSAQKVFDQAARLKGKVDAINIADSPMSKMRMSPISLSYLLQHNKDIETIFH
LTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDNGDHPF
>A0A8H7M098|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKLSEKLANHTSDAPYFTFEFFPPRTEQVCPVLTGHDSELTIFGIGILESSTRITGLASL
KPIAASVTWGAGGSTRDRSLDLAAFCQAENGLDTILHLTCTNMEKGTIDEALTTAMEKGV
STVLALRGDPPRGEEYWIPTDPRFQHAEDLVTYIKQHPKFGNHFCIGVAGYPDGHSEGGS
EEEQLTHLKRKVEAGAEFIITQLFYDVEKFKSWLRKVRNTGITVPVIPGMMPLQTYATFT
RMTDLCKATVPQHIQANLDAIKHDDQLVKEYGASLAVSMIRSILVDGDVKGVHFCTLNLE
KSVRKILDELGWTHGTHHPNQIITDASQSPHILPAPADAPHPVTFTISPSEATQHAATSL
AEHTRTGTLRTAAEAINSGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPPHVAISQWGR
PTTEQDLADLFLAYLNHKAPTTPFSPTPLSDESITILPHLISLTSKGLWTVASQPAVDGI
LSSDPVVGWGPKDGRVFQKSFVEFFATEEELVKIAKAIEDSGDGWVTFFAGNNDDGFLSN
IPDSGSNAVTWGVFPGQEIAQPTIIDRDSFLAWKASIYTWTMREIAIEYMEQDDAFMIWH
DFGLCYSPDSPTRKLLENVTKTRWL
>A0A8I1UEM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp|TrEMBL
MNLPISFEFFPPKTPEGAQKLRAVRQQLYARAPLFCSVTYGAGGSTQEGTFGTVREILAE
GVDAASHFSCIGATRAGVREQLAQLKAMGVKRLVALRGDLPSGYGLGGEFHYASDLVAFI
RAETGEDFHLEVAAYPEVHPQARSPEADLKAYATKVRAGAHSAITQYFYSADAYFRFVEE
ARALGADIPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIKSFGLDVV
TSLCEQLLRGGVPGLHFYTMNQSAATLEILRRLDTR
>K1RSJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|human gut metagenome|TrEMBL
DIEDTLIDMDFLGLHNVLALRGDKSQNERRFMPHPQGHAHAVDLVRQIAAMNRGEFVDGE
VEECHHSKFSIGVAGYPEVHFEARDITTDILHLKEKIDAGAEYVVTQMFFDNRKYFDFVR
RCREAGIRVPIIPGIKPISTLRHLEVLPETFGVELPGELVREAKAHPDSVREVGIEWAVA
QSRELMAAGVPVLHYYTMSRTNNIQQIVRTLF
>F6AR50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia sp. (strain Cs1-4)|TrEMBL
MSFPISFEFFPTKTPEGAAKHVQVRKNLYARKPQFCSVTYGAGGSTQAGTFNMVRDIQSE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPQSDLDAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A1Q4W699|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02056|TrEMBL
MTLGKPSTRTDRAATVRDLLATGKRSYSFEFMPPRNAEAEAGLWNAIRRLEALSPTFVSV
TYGAGGSTRERTVNVTGRIAQETTLTPAAHLTAVGHSVGELRNILGHYADQGVRNILALR
GDPPGDPLGAWVRHPGGVEYAADLVHLIKDSGDFCVGVAAFPEMHPRSPDWESEIRHFVT
KCRSGADYAITQMFFEVDGYLRFRDRLQKAGCDIPVIPEIMPVTSIRSLRRIPTLSTAAI
PTALSDRMLEHQNDPAAVRSIGIEHATAMCRRLLSEGVPGLHFMTMNFSTVTTEIYQNLG
LPRSG
>A0A374V2A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. OM08-14AT|TrEMBL
MRVDEVFKQAASQGTTSVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRSHADIAAKIDEYRSAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELANKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A2S7EBG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas euvesicatoria pv. citrumelonis|TrEMBL
MISTDTPNFASTVTEAYSLEVSAKDIGALTNAAPRILPGCAMFIPYLPGQNEAVRLAAAQ
RVRRLGFEPVPHLSARRIGSLEELQACVARLVDEAGVTRCLVIAGDPSTPKGPFPDSVSL
IETGVFERSGIGTIGVAGHPEGHPILRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
IVVTWLEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLASRLTQAHGDVRLHLFPFGGIAQSVQWVAHYHSRNASQDRTSAVRADRA
>A0A1S7HY04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygosaccharomyces parabailii|TrEMBL
MRISEKLQTQHSKSEKPTFSFEYFVPKTTQGVQNLYDRMDRMYQSTLPQFIDVTWNAGGG
VLSQLSTDLVETSQSVLGLETCMHLTCTNMPVSQIDEALESARLSGCQNILALRGDPPVN
QESWTPVEGGFRYAKDLVKYIRTKYGEHFDIGVAGYPEGHPENVNDKETLLDHLKEKVDA
GANFIITQMFYDADIFVKWCEDVRAMGIQVPIIPGIMPITTYAAFLRRAQWCDIHIPQEF
IDKLDPIKDDDQLVRDVGTDLVVSLCRRLLDSGHVRHLHIYTMNLEKAPQMILDRLGLLP
THDEPLDNHLAILPWRKSLNPQRRNEEVRPIFWQRRPYSYVARTSQWAVDEYPNGRFGDS
SSPAFGDLDLCGASLIRQSGKRSLELWSTPTSIEDIAQLVINYLRGELKCLPWSDTALNH
EVDDILPDLVALNQRLIITINSQPQLNGVKSSDPVYGWGPRDGYVYQKQYLEFLLPKDKL
PKLHEALANDVMLTYFAVDYEGNLTTNHRDGSRANAVTWGIFPGREVLQPTIVEKVSFLA
WKEEFYHICQEWKLNFENHQYNDSVNVLQRLINDYVLVNIVDNDFISPESRIFQLLSSI
>J7S3D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / KCTC 17520 / NBRC 10181 / NCYC 3082 / Yp74L-3)|TrEMBL
MSIKRLYDEKAGTSISLEFFPPKTESGRTNLLERIGRMSALEPTFITVTWGAGGTTADKT
LELAAVIAKAHPHIAVCMHLTCTNMEPHIIDAALERCKENGIRNILALRGDPPLELNHGD
AYGYFRHAIDLVRYIKQRHGDYFCIGVAGYPEGHYNVMDEDEQDPVRDLEYLKMKIDAGA
QFVITQLFYDVEKFLDFEKMFRDQVSQEVAVFPGLMPINSFMLFNRAAKLSHAEIPKHIL
DRFPEEIQLDDDLVKQVGVQVLIEIIDQIYERTEGRIRCFHLYTLNLEKAIAQIVSQSPI
LGHLIEDKSEGDINLEQEGANDGLVPKPGNDNAPIDTDRDVILVDDINDNMDLDSDVRKR
RRRSSVRSADVLMNRTTVDKYQTGSSLDTNDNNMPSKKFLISISKGSGTLGRDATWDEFP
NGRFGDSRSPAYGEIDGYGPTLKVSNKKAYELWGQPLSIKDLKDIFIKYLEGSIDALPWY
DQGLSPETALIQEELIMLNLRGYLTLASQPATNASRSSDKIFGWGPRQGVVYQKAFVEMF
VYKPQWENVLKPKLDHYGRRVVSYYVGDAAKHFDTNLDLGSSNVVTWGVFPNSQIIQTTR
IEEESFKAWRDEAFSIWSEWAKLFPRNTPTNSFLKQIHSDYCLVSIVHHEFIEPDELWEI
LLD
>A0A2E7NZB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp|TrEMBL
MSTHNFSIEFFPPKTAEGAEKLRATRARLAALAPKYFSVTFGAGGSTQQGTRDTVLEIIG
EGHEAAPHLSCIGSSRASLRAILEDYRSQGIKRLVALRGDLPSGYGAMDQASSEFRHANE
LVEFVRAETGDWFHIEVAAYPEMHPQARSPQDDVQNFARKVKAGANSAITQYFYNADAYF
RFVDEAARLGATVPVIAGIMPITNYTQLMRFSDMCGTEIPRWIRLKLASYGDDTESIRAF
GQDVVTQLCQRLLAGGAPGLHFYSLNQAGPTEAIWQQLVK
>A0A3Q9UXB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter festucae DSM 15932|TrEMBL
MTRARFEIIPSDGIGEKAERAFPDPAAVTLTVTSLPNHGTERTIDAAVELAGRGFRVVPH
LAARNVEGREALERALGRMRDAGIDEAFVISGDARSAAGSYSTSLELIRDARELRPELAV
DIAGYPEGHPHLSDESIATHLRERAPYIRGIVTQMCFDVDAVVRYADRLRADGIDAELWA
GVPGPVERTRLLSLGARIGVGSSLGFLKRSSSVAGGLLRGRRFDPAAFVGRLEAAAGDRL
AGLHVYTFNELDGLRAF
>A0A4Y9GI82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria sp. WF04|TrEMBL
MLNSKQRKKLSFEFFPTRTPEGRAKQVITRKQLSQFDPEFFSCTSGAGGSTKDGTMQAVQ
DILNEGVAAAPHLPCVGMQPHEITALLNGYKSLGVHHIVALRGDIPSGMGAGLDGLRYAN
ELVSLIKTEFGNDFHIEVAAYPEYHPQSRSAEDDLNNFVRKVKAGADSAITQYFYNADAY
FRFLDDVHGRGVDIPIIPGIMPIASFSKLARFSDTCGAEIPRWLRLKLQSYADDTASIKA
LALDVVTDMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>A0A1Q4WMG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02056|TrEMBL
MALGIASTRTDRALTVRELLAAGKRSFSFEFMPPRTEAGEQKLWDAIRRLEPLDPNFVCM
TYGAGGSSRERTVNMVGRIATETTLTPVAHLTAVDHSIAELRNIIGQYADQGVRNVLAVR
GDPPGDPMGEWVKHPEGVTYAYELVELIKGIGDFCVGVAASPNMHPRSTDWDEDIRHFVA
KIRSGADYAITQMFFEVDDYLRLRDRVAAAGCETPIIPEIMPVTNAKQLERFPQLSGSAF
PVDLEARLRAAIDDPAALRAIGMEHATAMAERLLAEGAPGLHFITLNHSTATLEIYQNLG
LHQR
>A0A368E8E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MNISFELFPPATSNGIGKVVEIARQLADFQPDMISVTYGAGGSGRERSSRLVAELNKPGF
PAITAHITLSGQSKQDVLQQMDEWQEHGVKRFVALRGDMPDMARPFKPHGDGFSSSLDLM
AHLASHGAEEIYGGAYPEGHPESPSQSAELDHLKAKQDAGATALITQYFFEVDCFLRFRD
RAESHGITLPIIPGILPVANFEKAKGFSKRCGASIPQFVHDRFAGLHNNPHESALMGASL
TAELVMELADEGVEHFHFYTLNRADLSLTACRMLGVRPT
>A0A350STS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp|TrEMBL
MALPVSFEFFPPKTPEGAEKLRAVRQQLYGQKPEFCSVTYGAGGSTQQGTFDTVGAILAE
GVDAASHFSCIGATKASVREQLTTLKAMGVKRLVALRGDLPSGYGIGGEFHYASDLVAFI
RAETGRDFHIEVAAYPEVHPQAKSPESDLQAFATKVRAGADSAITQYFYNSDAYFRFVDE
AHRLGVDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDIASIKAFGLDVV
TDLCDQLRNAGVPALHFYTMNQSVATLEIVKRLELG
>A0A435WRB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.002.01.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A853MHS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cylindrospermopsis raciborskii CS-505|TrEMBL
MQENHTTIHTSNSLTSFREAVQAGEFLITAEVAPPKGGDISHTIAMSATLKGRVHAVNIT
DGSRAVLGMSPLAVCAILCQHGIEPICQLACRDRNRIGLQADLMGAHALGIRNVLALTGD
PVKAGDHPDARAVFDLESVRLLQLITNMNQGLDFNHRTLVDGGLDLFAGAAVDPQSKSWS
GLQSRFERKVQAGAQFFQSQLITDFEKLEKFMDKIASSYNKPVLAGIFLLKSAKNAQFIN
KMVPGVNIPDHIIQRLAKAKYPLEEGMKIASEQVRMAKDLCQGVHIMAVKKEEAIAPILD
LAGVSR
>A0A8J6T402|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gorillibacterium sp|TrEMBL
SAASAAAISGNAARIAGRIAVQPVAPAAPAEPPAPAEPTLVDLVRQQHTVIVELDPPRDL
SIDRFMAAAALLKEAGVDALTMADNSLAMTRISNLPMGHLVQEKLGLRPLLHVACRDRNA
IGTQSHLMGMNAIGINHVLAITGDPARVGDLPDASSVFDMNAFDLIRMTKQLNEGIAFSG
KLLKQRANFVIGAALDPNVKYIEKAVQRMEKKIEAGAHYFMTQPVYDIEKIEKLYEATKH
LDVPIFLGIMPLMSGRNAEFMHNEVPGIRISDEVRRRMAGLNGEDGRQAGVGIAKELVDA
AISRFKGIYLMTPMLFAGMTAELTRYIKEKTGQ
>A0A4W5JMU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hucho hucho|TrEMBL
MVNQVQRVEDTWRTCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIR
NYGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVN
RRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPR
VNYHIVNVHVSSQLQVLHLHIL
>A0A2H5W5C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR11|TrEMBL
MKKSASFWDGLRERVLIVDGAMGTYLHMRGLPEGQCREALNLNNPSLVLSIHEEYLRAGA
DVLETNTFGANYVQLKRFGLEKRVRDINRAGVQLAREVATHGTGVFVAGSVGPLGALLQP
YGRLTLQDVQAIYEEQIGSLVESGVDLLFIETQSSTVEAQAAVRAARRVGRGIPIVCLMT
FDREGRSRMGNELPDALYELVEAGADVVGFNCGIGPGDAYDLVVRHLKDFPHPLCVMPNA
GYPTYVSGRLTYAATPAYFAEYARLFVEAGVVLIGSCCGTTPEHTAAMARVVKGAPPVRP
VVRPAPTSEQAPRPSLQLVEKPTPSEEVTFPTRLRDLFSKDVVVTVAVEPPRGWDYTRVV
EDVRYLRSLGVDAVNVGDNPLASLRMSPVALAAVLKREVGLEPIVHFTCRDRNVIALQSE
LLGAAALGLRVVLALTGEPVEVGEFPKATSVFDVDAVGLIRILRNLNEGRNLAGNPIDTR
THFIIGGSANPLAADMEREVERVRQKVENGASFLVTQPIYDPDVILRFQDALGDLAVDLI
VGICPPISERYARFLANEVPGISIPEAWIDRLRGRSREDAERAAVELCQALMERLRGVVQ
GFYVMLPMGRYDLVGALLGQASAHRPEARAERRRAE
>A0A7T8A3U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium diazoefficiens|TrEMBL
MTDLTTPAHTDGHFAVKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAGG
STRERTHSTITRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPAGG
IGTPYASHPDGYQSSADLVAGIKKRHADIEVSVSAYPEKHPEARDFDEDIDTLKAKVDAG
ATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARAFVTRAGTTVPDWFA
AKFEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAKS
AQKAA
>A0A7U7HFB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. JV274|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHPSAMDLVDQINNLGRGKYLHNEEQACDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREIGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A0S4RYN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter fetus subsp. fetus|TrEMBL
MLKDKIKENKPGILLYGITPPKINLSKDEAYQIAKKQLERLENTGIDGLVIYDLQDESAR
NDEKRTFEFCGTIKPEIYHKEFLKLSYPAVIYKAVGNYTKEEFANFLNTSNNDMLSVFVG
ASSKNDLLKFNLNEAYKLKKEQGGNVTVGGICIPERHEKKGDEDLRVASKIIKGCEFFIT
QAVYNIENAKRFLDDYANLGIKKVPIIFTFTPCGSPKTLEFMRWLGISVSKQFEDRLFES
DDPLSASVGLSLDMFEFLYKYGRAKGVSVGANVESISTRKVEIEASINLLRGIKNIIQNE
KECNLEELIQSASKFYE
>A0A6P0GII2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus normandii|TrEMBL
MKRTLTVRDPATRQSLRKAFDDLGYEVIPFKKTEQSVLSCVPKDVRLTVTASPAKGQDAT
IDLTVRLVGHGYTVAPHLSAQQIRDRAHLADVVARCREAGITDVFVVGGDPTDEPTEFRH
AHDLLVALHEIDHGFTEIGIGGHPEGHPTASTETLFQALKDKAPLATHIKTQIVFDPAVI
LRWARELKNRGIDLPVHVGVPGAVHRQKLLRVSGGLGIGESAKFLKKQQSLFWRFFIPGG
YSPNTIIKGLAPHIGKPDNGIEGFHVFTFNDLGPTEAWRQQMLRSLPDSGSADGPARPGP
ARRVP
>A0A2E8T895|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidaceae bacterium|TrEMBL
MKQISKILSKKQTISFEFFAPKELAAQDKLLEAIEKNNLNDLSFISVTYSVNKNSGPTDL
MVEKISKEIVVPVMPHLTCITHSKNEIATIIKRYQEKSINNILALRGDIPAGSQFFKNDF
DNALELVEFLRNKTKFDIAVAAHPEGHPDASDKKTDLLYQAKKINSSDFAITQFFFDPND
YFAFMDKLSKQGNDKPVIPGLMPPTNLSALIRMANMNGSHLPKSIIETLSSVNSKQEREE
FAKDIILKLVDQLISNGAPGVHIYTMNNVELSKQILNEITI
>A0A1V9V8I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. T|TrEMBL
MSQKERRFSFEFFPAKTEAGHEKLLATASQLAAKKPDFFSCTYGAGGSTRDRTLTTVLQL
DGEVKVPTAPHLSCVGDTKPELRALLAHYKDAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRAETGDHFHIEVAAYPEVHPQARNFEDDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAEKLGVSIPVVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDIASIQAF
GEQVITDMCERLLEGGAPGLHFYTLNQAEPSLALWNNLKLPR
>A0A430CVT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. S-NIH.Pt1_0416|TrEMBL
MTNTILTQAEAALAHEEPLFADVGGDIAVSFEFFPPKTEKMDAQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTLAAAAHLTCVEATREEIDQVAQEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPDSADQQADIDNLK
RKIDAGATRAITQFFFSPEAYFRFRDAAAAAGIAAEIVPGILPVSNVAQTRKFAGMCGAS
IPDWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKGFHFYTLNRAELAYAISHML
GVRGKKAETVAAA
>A0A0V7Z4I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. GXS13|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTDEMEKVLWSSIERLAPLQPKFVSVTYGAGGSTR
ERTHNTVARMIRETTLKPAAHLTCVDASREEIDAVVQAYWDVGVRHIVALRGDPADGVGH
AYKPHPEGYATTAELVEGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQA
ITQFFFENEVYLRYLEKVRAAGITIPIIPGILTVQNFKQSANFARRTGASVPYWLAARFE
GLDNDVETRRLVAAAVAAEQVLDLVDEGVQDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AEKAAA
>A0A4S2T230|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. A1136|TrEMBL
MALGTASTWSDRAHTVRDLLASGSSYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSVT
YGAGGSTRGGTVRATEQIAANTTLTPVAHLTAVDHSVAELRHVIGQFADAGIRNMLALRG
DPPGDPMGPWVKHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVQKAGCETPIIPEVMPVVGIKQLDRLPQLSNAVFP
EAVKDRMLAVKDDAAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A5B7YAB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinimonas iocasae|TrEMBL
MVSFAQGIDALNQSLSELRDIDVSFEFFPPKSQQMEETLWKSVERLAPLKPAYMSVTYGA
NSGERDRTHDVVKRIHQQTGVAAVPHLTCVDASKEELRQIAQDYWDTGIRRIVALRGDLP
KGVDKTEMYASDLVALLKDVADFDISVAAYPEKHPEARNAQFDLLNLKRKAEAGASEAIT
QFFFDPSVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKQFEGL
HEDDHTTRNLLGANIAMEQVKVLAQEGIKHFHFYTLNRSELSYAICHMLGARG
>A0A3N0E4L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinomicrobium pectinilyticum|TrEMBL
MKVTEHIEQARGKTLFSFEVVPPPKGGNIQELYNNIDPLMEFNPPFIDVTTSREEYIYIE
RDGLLDRKIVRMRPGTVGICASIKHKYQVDTVPHVLCGGFTREETEYMLVDCHYLGIENI
MALRGDAMKHQRYFEPTKGGHTYANELVRQIKDITRGKYLHDVVEASNRPDFCIGVAGYP
EKHLEAPSLDYDLKKLQDKIDAGADYIVTQMFFDNSKYFEFVEKAREMGINVPIIPGIKP
IAVKRHLQLLPQVFKIDLPEELIHAVESCKDNKEVRQVGIEWCIQQSRELKDAGVPVLHY
YSMGKSDNIKAVASSVF
>A0A351AZ17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MRPMNKFQDALKSGKFAVTAGLTPPKGVNLAPFRQQVDALKDRVDAITISDNRGAHLAMS
SLAASALARQQGSEVICTLNCRDRNRLALAADLLGAYALGIENILPVSGDYLSFGDSPHA
MPVFDLDSVQVLEMARSLENGTAPGGQDLNGAPVFFLGGVANPEAKPLPPQVMKCLKKIR
ARADFLITLDVYDLQKLEAFAAQIDLVEARLIAGVRLIGPGDVARQASGNPPGNLIPPEI
MSEFQSLEESRAFDLGKRRAVEMIRSIKTRKLAHGVYLRADLHPEMIPEVIAAAEM
>A0A824ZUV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLNKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A806GRR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium diphtheriae (strain ATCC 27012 / C7 (beta))|TrEMBL
MSAQPLPAAYQRTITDVISMPTPGQVPFSVEFMPPRDEAAEERLWKAAEAFHDLGASFVS
VTYGAGGSSRERTMRVAHKLSRHPLTTLVHLTLVEHTQEELEEILCTYASHGLSNLLALR
GDPPGTDPMAPWVPTAGGLDYAKDLIDLVRKTEQTSHFQVGIASFPEGHYRAPSIEADTQ
FTLEKLRAGAEFSITQMFFDVDHYLRLRDRLVKADPEHGSKPIIPGLMPITSLRSVRRQM
ELAGATLPKALEKRLLDAARGDEEAHRGDIRKVGIEVTTEMAQRLISEGIPDIHFMTMNY
VRATQEVLHNLGMAPAWGTQQGHDAIR
>A0A7Y0WDF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. WS 5503|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFSPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A6L8KNV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. CY15W|TrEMBL
MDNPNFSIEFFPPKTPEGAEKLRATRTKLSALKPKYFSVTFGAGGTTQRGTLDTVVEILA
AGEDAAPHLSCVGGTRESIRDILAEFKSHNIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGDHFHIEVAAYPEVHPQARSPQDDLQAFERKIKAGANSAITQYFYNADAYFQFVE
QTNKLGINVPIVPGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTALCERLLKGGAPGLHFYSMNQAAATTALWQRLV
>A0A825M4W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MLKNKIKDNTPGILLYGLTPPKLNLTHEEAIIVAKKQLERLENRGIDGLVIYDLQDESNR
NKSERTFEFCGTIKPEIYHKEFLKLAYPAVIYKAVGNYTQDEFCRFLNDSGENLSVFVGA
SSKKDSPKLSLDMAYKLKKEQGRDITLGGICIPERHEKKGDEDLRVAGKTIKGCEFFITQ
AVYNLENAKRFLDDYSNLNIKKVPIIFTFTPCGSLKTLEFMRWLGISVPKQFENRLFKSD
DPLKASISLSLDMFEFLFKYGKAKGISIGANVESISTRKVEIEASVELVNGIKSIIS
>A0A330M6M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella benthica|TrEMBL
MGFHHAQHSTSLNQSLAELNGDINVSFEFFPPASPEMEKILWNSIRRLEPLKPKFVSVTY
GANSGVRDRTHGVIERIQRETDLVAAPHLTLVDASDEELVELAKHYWNSGVRDIVALRGD
LPDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDATNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDAEIIPGILPVTNFKQLKRFAGMTNVSIPGWLHKQFE
GLDDDPATRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGA
>A0A7X7IL86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MNHGIDIAGNSFSPPVALTICVGANPVAADLEREIERFKKKVDAGAEYVITQPVFEPKML
LEFMEATKSHRIPIVAGIWPFTSFKNAEFMANEVPGVVVPEALLKRMSAGKTREAGIRIG
IEIAREMIETISPYVAGFAISAPFGNVKIALASLGKIGLDEVD
>A0A8I2GRL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae|TrEMBL
MMIAPQSESREEAPLADLLSHYSIEVTSRDLQSLESMTATLPQGCEVFIAHLPKEDIGLL
VRAAAGLRDAGFVPIPHIVARNIRNRLELDTMLARLSEEAGVRHALVLGGDRDDAAGAFG
SSLELIETGLFQAYGIDRIAIACYPEGHPRIAGAILDAALTAKIDAAARAGLDVLLVSQF
LFDPKPLLNFARRLRERGVTAPLSVGIAGPASRTKLLKYALRCGVGASLRALRERSEIAR
NVLSGETPEELLMEIAAAQATEPDLGISGVHFFTFGDPAQSIRWAEQQVDR
>A0A0T6ZQX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. GL28|TrEMBL
MSPDINPFDPGAPLEPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGIHV
MAYRQEEYVAEIVHESGVLKGRRPWKHETLPEDALVAERLEHIREGKEENQQQMAEAAAH
HPH
>A8HVP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)|TrEMBL
MMSGPVRASRELGKAPVSVSFEFFPPKTEEMERTLWASIDRLAPLCPNFVSVTYGAGGST
RERTHSTVARIVKETSLAPAAHLTCVAATRAEIDEVVRSYADAGVKHIVALRGDPTTGVG
TKYEPHPGGYAYAADLVAGIKKLGDFEVSVSAYPERHPESPDADADIDVLARKVDAGANR
AITQFFFDNDVYFRYLDKVRARGIDIPIVPGILPVTNFKQAARFAAATGASVPDWFAARF
EGLDDDPETRKLIAAAVAAEQVMDLVDRGATDIHFYTLNRADLVYAVCHLLGLRAQAAAA
PATAA
>W7P3Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. DC4|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKGVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A2E0J690|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor sp|TrEMBL
MPQQRFSRQPDVSGKLRVSFEFFPPKTDAMEARLWETVKRLEPLSPSFVSVTYGAGGSTR
ERTARTVKRILEETQLTPAAHMTCVDASREDVDQVVGEFVDMGVKRFVALRGDPSAGVGA
AYRPHPDGYANGAELVGAMKRQGDLDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGVLPIHNFTQVANFAGRCGASIPGWLAERFA
GLEDEPQIHALVASAVAAEQVLDLMERGIDDFHFYTMNRADLVYAVCHMIGIRPRSASKV
EQPAAA
>A0A5T1T6T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQKCKEKNLNQILALRGDVCNDLEKSKDFSYASDLISF
IQKQGEFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A1I4TPE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. Rc3b|TrEMBL
MTDLTIPARADGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTPYSSHPDGYQSSPELIAGIKKRHGDIEVSVSAYPEKHPEARDFDDDIDTLKAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARAFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A698FEH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIADILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IQKQGKFEIYAACYPEKHNESRNFIEDIHHLKNKVNAGTDKLITQLFYNNEDFYTFKQNC
ALANINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAV
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEEIRA
>A0A1G1K7A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica bacterium RIFCSPLOWO2_01_FULL_50_24|TrEMBL
MRVTELYKGKQPDISFEFFPPKTDEGEQKLLETATSFKALRPSFISVTYGAMGTTRDNTI
RIVEAIKNEIGIESAAHLTCVGHTKREIESVLEELHAKGIENIVALRGDPPKGEAEFRPV
RDGFRYGSELVHFIRSHPKYRDAFALAVAGYPEGHQECRDLKKDLKHLKHKADQGADVIV
TQLFFVNKDFFDFVDRARAIGITQPIIPGIMPVTHGPQIQRFAKMCGAKIPREMNEAIER
FGEDQHSVEAYGIDYATRQCGELLKGGARGFHFYTLNKSRATSQICRNLGLDRR
>A0A4R5C9A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiangella asiatica|TrEMBL
MALGLPSTMPGGARTIRDLLASGERSFSFEFFAPKTEQAEVSFWQTMRELERLRPTFVSV
TYGAGGTTRDSTVRVTEGIARDTTLTVVGHLAAVNHSVAELRNVLGQYADAGVRNFLAVR
GDPPGDPRGEWVAHPEGLEYSEQLVQLIRAHGDFCVGVAAFPEKHPRSPDLDTDVRFLVR
KFQSGADYAITQMFFHADDYLRLRDRVAAAGGEAPIIPGIMPVTNVKQIQRFSVLSGADF
PAPLAERLLAVEDDPEAVRSIGIEVATQLCERLLAEGAPGLHFITLNKSTATRRIYEELG
VSAFP
>A0A2D5E397|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MSDFPFAGPPSVSFEFFPPKTPRGWGLLDQRIDELFPLDPSFVSVTYGAGGTTQERTHEL
VERLAHETPLDPVPHLTCVGQSKVDIDRILERYVEAGVRSILALRGDPPIDGSPAPIGEF
THAADLVNHLRNFADRNRWELSIGVAGFPEGHPDTPDTLLAMEHLAAKVDAGADWICTQL
FFDNHAFHDWRDRCQLSGIRVPIIAGIMPIASRSGVKRMAQLAAGAVFPASLLRAVSRAE
EDDDDAVAQIGVHWATEQCRDLLDHAVDGLHFYTLNKSNATLQIHRALGVRTSRQLRSV
>A0A8F0CFS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. diarizonae serovar 60:r:e,n,x,z15|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATGDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDIYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2U4AZN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tursiops truncatus|TrEMBL
MDRPKPKVLPAGHCCPSLGMRAWEAGSARFSVTPSISRSSAMVNEPRGHGGPSPRWEGSS
SGSESSKDSSRCSTPVLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKRLGLKNILALRGDPIGDQWEEEDGGFNYAVDLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEAGLKHLKEKVAAGADFIITQLFFEADTFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDDAIRNYGIEQALSLCRELLASGSVPGLHF
YTLNREVATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPGGGYVFQKLLERLFHGTFPNWTKGWQTSLRPVQTEKPHVPAPLPLLMGSTPN
>A0A1F7WWD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Wallbacteria bacterium GWC2_49_35|TrEMBL
MSFEKPDFMNILNEDRIMIFDGAMGTMLYSKGIYINRCFDEMNLSAPNVISDIHAEYVGA
GAQVIETNTFGANRCKLAPHGFAEQLEAINYQGAKLAVQVAKAAQHTVYVAGSIGPLGIK
IEPWGKTSVDEACEFFREQAEALLAGGVDLFVLETFSDINEMHQAIRAVKSLCNLPILAQ
IKIGNDGNATYGTTPEVFTQNLDSWGADVIGLNCGVGPKIMLDTIELMSEFTKKKLMVRP
TAGLPTSVDGRTMYLSSPEYFAEYTKRFIQHGVRIIGGCCGTTPAHIKAMASAARMFTTG
ERKISVMVKDAPKKPLPQAEPIAKEKKSKFAASVCAKKFVVTVEISPPKGCDATRALESA
KFAKENNIDAINIPDGPRATARMSPQALAGIFERGAGIETILHYCCRDRNLLGMQSDLLG
AYASGLKNVLLITGDPPKLGDYPDATAVFDVDSIGLTNMVHRLNSGCDLGGNPIGKPTGF
FIGVGANPGAIDLNLEIKRFEYKVEAGAEFAITQPVFDIALLENFLKRIEHVRVPIIAGI
WPLASLKNAEFMNNEVPGMSIPEHLMKRMRTCDSAEKQREEGIKIAREALAALKDMVQGV
QISAPFGRVATVLEVIDGIVAH
>A0A1E5GB67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus termitis|TrEMBL
MRTDTLFKEKTVFSFEIFPPRRTAPVDTIYHTLERLKGQHPDFISVTLGAGGAGNNLSTA
DIAQKIQEEQFLPSVAHLPAVNFSKDEVIAILDELTQKKVENILALRGDILPDKEPKKDF
TYANDLIAFIHEQGKFNIIGACYPETHSDAASSVADIQNLKRKVDAGTNQLITQLFFDNH
YFYTFKEKCEIAGINVPIQAGIMPVVNKKQIERIVKMSNVTLPTKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVAQGVDGIHLYTMNNPYVAQKIREATRSLFEV
>A0A3A3Z808|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter chuandaensis|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A242LEP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus termitis|TrEMBL
MRTDTLFKEKTVFSYEIFPPRRTAPVDTIYHTLDRLKGQQPDFISVTLGAGGIGANLSTV
DIAQKIQEEQFLPSVAHLPAVNFSKEEVIVILEELKQKKVENILALRGDILPDKQPKKDF
MYANDLVAFIQEQGNFNIIGACYPETHGDAVNSVDDIKNLKRKVDSGTNQLITQLFFDNH
YFYTFKEKCEIADITVPIQAGIMPVVNKKQIERMVTMSNVTLPMKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVAQGVDGIHLYTMNNPYVAQKIREATRSLFDA
>A0A1H7MP51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimarina amphilecti|TrEMBL
MKVTDHIKNAKGKTLFSFELIPPQKGKSIQELYNNIDPLMEFKPPFIDVTTSREEFIYID
KEGLLDKKLTRMRPGTVGICASITHKYSVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFNPTKGGHCYANELVEQIVNMNNGRFLHEVIEGDNQSDFCVGVAGYP
EKHLEAPSMDSDIRRLKDKVDAGADYVVTQMFFDNKRYFDFVEKAREAGINVPIIPGIKP
VAVKRHLQLLPQVFKLDMPDELVRAVESCKTNKEVREVGIEFAIQQSKELMEYGVPVLHY
YSMGKSDNIRKIAANVF
>A0A516WEF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium SJ-26|TrEMBL
MTDAYSLEVNAKDMPALTAAAPRIAPASIVSIPYLPGQDNDTRLAAARAVHKLGFDAMPH
LSARRVTSLTELDLFIKRATIEAGVEHCLVVAGDPPSPMGPFPDSLSLIETGIFERSGIK
VIGVSGHPEGHPVMDPVHRWDALEKKCHSIAMRGMTPLIVTQFSFDADSVLTWLKALRER
GLDHPVRIGVPGPAGITVLMRYAALCGVSACTSMWSKYGFSMGKLLGTAGPDLFVDRLAA
GLTEAHGKVNLHFFPFGGIAQSAGWIEQYRSRRGKTAS
>A0A3B9VUE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKVIDLIQAEKPCLSFEVFPPKTSDNYQSIQTATENIAALSPDFISVTYGAGGGASDYTV
SISANLQEKYHVPTLAHLSCISSSHEGVQKQLAAMRAAGIENVLALRGDIAPNAPAAPNW
YYHYASELVREIKSYGGFCIGGACYPESHPESKSQAEDIAHLKEKVDAGCEFLTTQMFFD
NNIYYNFLYKVREAGITVPVVAGIMPVTNVKQIKRIVELSGTALPQRFRYLLDRFGSNPA
AMKQAGIIYASEQIIDLLANDVPAIHVYSMNNVSVAAQIQSNLSEILK
>A0A0Q7GCC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia sp. Root1293|TrEMBL
MAIELPSTEDAARLPVSFELYPPRTDAAAIALGRTIDRLTEVDPAFISVTFGAGGSTRDR
SLTVLSYILENTRVEPMAHLTCVGSSAAEANRLVRQFLDAGITSFLALRGDPPLDGTPLS
VGDLQSAAELVQLIHRVQQEREPFSQEAVRGTPGGTRLRARPRPERVAVAAFPNGHATSR
GPQQEIDALLAKQASGANLAITQLFYRADDYLAFVERARAGGVTIDILPGIMPAASAPRL
RRIAQLTEEEAPDDLLIALEIEPTEEGRSEIATSFFSDLAAEVIAEGAPGLHLYTHNRHT
PVLDVLERLDRLPRTARGHIKENA
>A0A261FE95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium myosotis|TrEMBL
MHTPMFSLEVFPPKRNAPVGTIYDTLDGLEGLEPDFISVTYGHGTHTDRTATARIANTIR
NEYGIPAVAHLTALYSDRDKVDEALDMFEQAGVQAVLALRGDYIEGEEPVGVFEHASDLV
AYIRERKPELKVFGACYPEGHYQSSSLDEDITNLKTKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGAKSVRRMAERNASRIPDHLAVMLDRWEGNADAMRAAGIA
YASEQITDLVAHGVDGIHLYSMNHPATTRRIWRNVEPLFAV
>A0A4S9MWK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MTKLAVTRAIMHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRM
AHSLRPLFVNVTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAK
ALGIRNILALRGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVA
AYPEGHSDQSHPEHQHATYDLPFLVEKVEAGADFLMTQLFYDLHAYQDYEKLLRQHESGA
FKTIPIIPGLMPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMV
ETLKKNSYSGPKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAK
ARRRSSIANSAPQNRVVIDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEG
ALGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPIDTKDITSIFAR
HVRGELDAIPWSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPN
GFVFQKPFVEFFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTG
KEIVTPTMIEAVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFT
ENNGLWKMLLEA
>G9WMJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oribacterium parvum ACB1|TrEMBL
MSIVDLFQDKTVFSFEVFPPQRNASIETIYDTLYDLRDLRPDFISVTYGAGGGKNNVSTV
PIAEHINDICHVPSVVHFPCVNQSKKDVLEKIEELKAAGIENILALRGDIPEGERNQGDF
RYASDLIAFLREHGDFNISAACYPEGHLESPDKVEDIRNLKNKVDAGVNHLISQLFFENK
HFYIFQERCALAGINVPIEAGIMPVINKRQVQKMASLCGVNVPKKFQRILEKYEDNPVAM
RDAGIAYAVDQIVDLVTHGVDGVHLYTMNNSYIARKIYKATHSLFESTNKGAKKASSSA
>A0A3R7RLM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium TMED72|TrEMBL
MHISDILAKGPTCSFEFFPPKTEKGAETLYETIQQLENLRPSFVSVTXGAGGSTRDLTHD
LVVRIKDSTSLDPIPHLTVVCHGEDEIRSILERYAQANVSNVLALAGDPPANKVDYNRKH
DAFQHAGDLVRFIRRFNEEGHHSSERGFGIGVAGFPEGHPTTPNRLVEMDHLKAKVDEGA
DYIATQLFFDNGAFLDFRERCALAGINVPIIAGIMPVTSIKGMHRMAELALGANLPAALQ
RAVARAGDDSEAVARVGTHWATEQCRALLDQDVAGIHFYTLNQSSATREIYRNLGLRDSE
GLQA
>A0A0F6B9U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium (strain 14028s / SGSC 2262)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6N7ZEP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulosimicrobium composti|TrEMBL
MPPRRPDAAPKFWETARRLVATHPDFVSVTYGAGGTDRATARQVVGRLLQGTPVLPIAHL
TCVGASREDVEEVISDFLDEGVRSFLALRGDPPRDQPDWQPAPDGVRSSTELVALLREVE
ASRCASDPAVALRGAARPLTIAVATFPDGNPAARTTRTQEVRRLWQKQQAGASFAITQLF
YDASSYTDFVAEARAAGVTIPILAGLLPTTEPARLRRVEELTGVRAPQRLLDALDALPDP
EAQHAYGIAYSVDLAQRVLDAGAPGLHVYTFNKHRAALDLLEGVHLGGGSRGTGGSTSAA
AAPLVPDLASGPWVTGTSLPTTGAATHGTPV
>A0A6G2V8T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID2563|TrEMBL
MGPVADRPTYSFEFFPPRTAQGERTLWQAIRRLEPLGPDFVSVTYGAGGSSRDRTIEVTK
RLVTETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPKGEWTAHPDG
FHHAYQLVELVRSLGDFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFDV
EDYLRLRDRVAAAGCTTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAQHRPDI
AYEIGVAHATLMADRLLAEGAPGLHYITLNKSTATLDIHRNVMSTRSLHAS
>A0A7Y3EAD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp|TrEMBL
MFDFPYIIELLTPKKTDDQYPERLLNRFGERFTRAIESGCAVSIPDNPMGNLRMGALETI
EMLNLTFDPERLVINLNTFHLKDELDEILEGALQTGIRSLLVIRGDGGPDLSRLEPAHIG
GKFNVASSTDLIDYINRAYPGKFMTGAAFNHYNPIEVELKRLDKKIGAGAQFIVTQPVIG
NDSRLNQLTARDIPLVVEAWMSNNIELFSQSVGDDTLSIADYDPIDNLNLLHDSFPDSCI
YLSMLNFNEKFEELLPAL
>A0A4R0FSZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter quasihormaechei|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATGDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMFAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A147EQF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter chromiiresistens|TrEMBL
MNSFLLPARAATRARFSFEVFPARSGAAALALGHAVQHLSAADPDFISVTYGANGSNRDA
SLDLVAYLRDHTDALPLAHLTTVGETHEAVRAAIHAIMDAGVHDFLALRGDPPRGLDEGD
ARVAGSMSSWELVRLISEARAERPPLTSVGRTAVAAYPNGHPLSRSRSEDVDWLVAKQEA
GANLAITQLFFRAEEYLSFVEEARAAGLTIPVLPGLMPVSTSAQLRKVASLAGRPAPAEL
TRALDAEGGYAPELGVEHTVSLARELLDGGAPSVHLYTFNRHEQVLAVLRELGLLTPDPV
>G0HEB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium variabile (strain DSM 44702 / CIP 107183 / JCM 12073 / NCIMB 30131)|TrEMBL
MSPAPSPESLSTTPPPPSLQVAVSDTLKRGTPGRVPFSVEFMPPRDDAAEARLWSAAEAF
HDLGASFVSVTYGAGGSSRSRTERVAGRLAVKPLTTLLHMTLVGHTEEELRGILREFASL
GLTNLLALRGDPPGDPTGEWQGIAGGLSHAVHLIELVRSMPECEDFDMGIASFPEGHYRA
ESIEADTRYTVEKLRAGANYSITQMFFNVDHYLRLRDRLAACDPVHGAKPVIPGLMPITS
LRSVRRQVELAGCELPRDMEELFTKVADGDERKNAAAIREVGIEVTTKMAERLIAEGAPD
LHFMTMNNVRATQEVLHNLGMAPAYGPKFGQDMVR
>G2P6N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces violaceusniger (strain Tu 4113)|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRAELRNIIGQYADAGIRNMLALR
GDPPGDPTGEWIRHPDGLDYAVELVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATEVCARLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>A0A2P8DIE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloactinopolyspora alba|TrEMBL
MSAVTVSMPKVRGSRARRVSSPLPGEPRYEILPLPGVLDALAELPAGAAVTVTASPRHGV
DATVELTERLAAQGLRAVPHLAARQIHDHTELALVVERLTAAGVLDVFVVGGDATEPAGE
FPDGLALLRGLDALGRPFEHVGVPSYPEGHPLIDDDTLWTALADKEPYATYIVTQMCFDA
DTICDHAAEIRRRGITLPIVAGVPGVVDTAKLLRVSLRIGIGDSVRFIRKNRSTTVRLLD
PRGFRPDALTRRLGEHVRAGRCDISGLHVYTFNHIGPTVRRMARLHSPETEVTGWSSPRT
SRSPAARSSSR
>A0A2P8E2H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloactinopolyspora alba|TrEMBL
MVLEQLPTSPDAAQSVGELLASGEQSFSFEFFAPKTEDGETTFWRTIRELERLSPTFVSV
TYGAGGTSRESTVRITDGLARETTLTTVGHLTAVNHSVAELRHVIGEYCDAGIRNVLALR
GDPPGDPGAEWVKHPEGFEYAEELVRLIREMGDICVGVAAFPEKHPRAPDVETDAKFLVR
KFRAGAEYAITQMFFHVEDYLRMRDRVAAAGGEAPIIPGIMPVTNVRQIERFATLSGADF
PADLAERLMAVEHDPEAVRSIGVEVATKLCERLLAEGVPGLHFITLNRSTAAREVYEALG
LANRTT
>C6VSJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / CIP 107007 / KCTC 52180 / NS114)|TrEMBL
MFLQKIKSRESGVVLYGITPPKADTTADRVAEIAHKTIERLSSLDIDALVVYDVQDESAR
TKEERPFPFLNALDPLVFASEFLGALNVPKIIYRPAGKFSPDELSDWLEQLHDQSFYPVF
VGVPAPDFPVKTSLPEAYQIWRKHEATSAIGAVTIPERHKVLQDEDVRILDKMECGVSYF
ISQCVFDLEYARQVIEDLAQRCERQQVSPPTIIFTLTACGSEKTLQFMEWLGIHVPDALK
DDFRKSEDILDKSVNVCLDIASALTSLCIERAIPFGFNIESVAIRKAEIEASVYMARQIS
EMLKEKGVRKPSAPELVRDQQ
>A0A6G7RSA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesoflavibacter sp. HG96|TrEMBL
MKVTEHIKNANGKTLFSFEIIPPKKGNSIQQLYNNIDPLMEFKPPFIDVTTSREEYVYIE
KEGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIENV
MALRGDAMKHQQYFEASKGGHQFAKDLVGQIQNLNKGKYLHDVIEVDDKADFCIGVAGYP
EKHIEAPSLKTDLKRLKEKVDVGADYVVTQMFFDNKKYFEFVDAAKQEGINVPIIPGIKP
IAVKRHLQLLPQVFKIDLPEDLIDAIDNCATNEQVRQVGVEWAIQQSKELQNAGVPVLHY
YSMGKSDNIKAIAKAVF
>A0A3B7LYW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter chinensis|TrEMBL
MSSLTHYLSQQQFCFLVEYLSSDTTHPVAQEIAGFPALMTLVDRVHSDEDPAPLNVAQRY
PSSIEKIIHFAGKDRDIADFEIFLNQAKQQGIQNLLLLTGDKLKQHQYGSAHLKRTRYLE
SINAVVHAKQKGGFCIGVAFNPFKYAEAERDAQYFKLHKKIKAGADFIITQLGYDLSALK
QVKLFLSQQQVQLPILACVMPLNLARARYMVKQQVAGIVITPHMLNILEREKQQGLTERV
YIRCALQILICQHLGLAGIHLSACYKKEEQEVLTRHIDQYRDLSLVECEYLWNSLWEIKT
GKELIPVLRYYSKPAPSTDILKYQHLHFMHEALFNSRLGSGMGKFIFQQPIWSNKFVART
LLKTEELSKHSVLGCESCGQCRLGETLYICPETCPKGLANGPCGGTILDRCEFGDRECIH
SVKARLAKAVEQTEILKNKLIPTVPVEVRGTSSWKNWYLSRQA
>A0A7X5L5A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium MD335|TrEMBL
MKTAELFKKKTVLSYEVFPPKTTDDAHTIYEALDGLQGLCPDFISVTYGAGGGTNCAKTL
DIAAAVKKQYKIESVAHLRGLDLSRDEVLQIIGELNEKGIENVLALRGDAVQDTVPAGDF
KHADELIAYIRAHSDLNILAACYPEGHPECKSLAQDIAYLKRKADAGASQLITQFFLDNE
DFYGFLEKVRAAGITLPIQAGIMPVTNRKSIERMVKMCGIKLPKKFMRIMDRYEHSPAAL
RDAGIAYAIDQVIDLLAHDVDGIHLYIMNKPYTAKRIFEAVQNIISA
>A0A7S0IBI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonas pusilla|TrEMBL
DVHGSVRPHRACTAAHRRSHATMDVGLVDALCDYSRPVFLFGLTPPLEGATQDELKETAR
KFVERSATLATDGFIVYDIQEEKGRTPEPRPFPFRKLDDPSHFAQVLKDVSGKESVVYKC
VAESDPGGFDGWLNKAIDDYGVNAYNLVGGASSANQYSGPTIPDVAAKLNKRKQCAHGGV
TIAERHIKKGNEHETLVKKGELGMQWFISQAIYDPEPMIKLLKEYGALCRQRNIEPKRVV
LTFAPCGREKTMRFIKWLGVTVPEDIEREILDAEDKVGKSVDLLCAMCKKILDETKGCGV
PLGISVESVSIFKNEINAAHELFRRTQSMLLDFLGEPWLVQYKLVSKGVKRTSFDYGSRK
PPASPGAALPPVKEPKAAKKEGGIGGLFEGLSEEEQKKLGIAGAVGVVVGFILGAVLGGS
KSKPVAPAPEPPKKKGWGK
>A0A5C4LJQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium terricola|TrEMBL
MYPTAFRPSRESRRPIRVSFEFFPPKTPEMEATLWSSIERLAPLGPSFVSVTYGAGGSTR
ERTHNTVSRLVRETDLKPAAHLTCVAATKAEVDDVVRSYHEAGVRHIVALRGDPAEGVGT
AYTAHPGGYERSCDLVAGIKRIGDFEVSVSAYPERHPEAGSLDQDLDALKAKVDCGADRA
ISQFFFDNDLFFRYLDRVQSRGINIPIIPGILPVQNFKQAANFARRTGASVPDWLAARFE
GLEDDVATRKLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRAAPAAAE
KAAA
>A0A0R2WF21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR92 bacterium BACL16 MAG-120619-bin48|TrEMBL
MNSSPLLSFEFFPPKTDQGKVNLATTRKELGKFSPEFFSVTYGAGGSTRSTTLDQVKAIL
ADGYDVAPHISFGGSSEDEVLTLLNDYKAMGVKNLVALRGDLPSGMGGAGQLVHANQLVA
FIRAKTGNHFNINVAAYPEIHPESESYSRDIFWLGEKFKAGANRAITQYFYNADGYFKFV
EECAKAGIGAPIIPGIMPLTNYANLVRFSESCGADIPRWLRWQLKERSSNQEDLISYGID
IISELSQKLIDGGAPGLHFYTMNQWQVTDILCRNLGFSETV
>A0A562LF93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas cucumeris|TrEMBL
MRIPVSFEFFPPKTVEQREQLDKVAVRLKKLQPEYVSCTFGAGGSTLDYTPETVHRLHHT
HGLDAAPHISCVGGTRAELGALLERYKGMGCKRIVALRGDLPSGMGHTGDFRYATELVEF
IRREHDGFFHIEVGCYPETHPQSEHALADLKHFKTKIDAGADGAISQYFYNADAYFRFVD
DARRMGITIPIVPGIMPISNFSQLRRFSETCGAEIPRWIGKRMLGYGDDVDSIREFAADF
VADLCRRLVEGGAPALHFYTLNLSKPTLSVLSRLDA
>A0A1F8MR71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_52_14|TrEMBL
MKQGFREALKSGEFIVTSEIGPPKGTKLEKMRHHIEILKDRVDGINVTDHQSSVMRFPSL
GGCLEIKEHGGEPILQMTCRDRNQMALQADLLLAYTRGIKNVLCLTGDAVPVGDHKQAKG
VFEFDSVQLLRAIRQMESGKDMGGNDLDGAVEFCAGAIVTPEAKPIEPQLIKFEKKIEAG
AEFIQTQAIYDLDNFAKFMKNARQYPVKILAGIVLLVSAKMAKYMNENVPGIFVPQNLID
ELAGAPKGGALQKGIEIAGRMIKTIKEEKLCDGVHIMAIGKEEVVPDILAAAGLNGHMK
>A0A1P8U9P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium aurum|TrEMBL
MRASAADRLTDPDPRATMTRATMFLPETSPDTPVPADAAAPFSFEIYPPRTAAGLPALYE
TIRVLADAGPRFISVTFGAGGSTTDRSLAVLTHILRETAVPPVAHLTCVGSTYADATAVI
REFLDAGITRFLALRGDPPAGTAEEDIYLGDLESAAQLVQLIDRVQAECSPYREQEIPGV
PGAARVQPASRVEIAVAAFPNGHPRSRHRFEDIDALLAKQAAGATSAITQLFFHADEYLA
FVERARAAGVRIPIVPGIMPITSPARLRRVLELTGDPRPDDLGEALETATEAAAQRAVGI
AHAADLARAVLDGGAPGIHLYAFNNHETVLAVLRAAGLIEQETLA
>A0A239D1W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tardiphaga sp. OK246|TrEMBL
MTEINPATPTKLPNISFEFFPPKTEEMDRTLWDTIERLAPLNPSFVSVTYGAGGSTRERT
HATIVRLLKETALTPAAHLTCVGAPKSEIDDVVTRYHEAGVRHIVALRGDPTTGIGTEYI
PHPDGYKTSADLVASIRNRYPDIDVTVSAYPEKHPESADFDADIDTLKAKVDAGATRAIT
QVFFDNDLYFRYLDKVRARGIDIPVLPGIMPMHNFKQARAFVTRAGTTVPDWLTAKFDGL
DNDAETRKLVATTVAAGQVQKLAKQGVSDFHFYTMNRADLVFAISHLLGFRPNGAQKAA
>A0A502MJ17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B4-1-3|TrEMBL
MNQFRFSRRRDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDSVIREFADMGVKRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSLRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>A0A1M6QZE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium johnsoniae|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAIDLVRQIKDLNCGQYLHEVIDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A243DAC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar subtoxicus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGTLLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRLIEQGMRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMQYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>C4Z117|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospira eligens (strain ATCC 27750 / DSM 3376 / VPI C15-48 / C15-B4)|TrEMBL
MKYTGTAGILYDRLKSEILVADGAFGTYYAKKYDTGSLPELANLQASDRVLAIHKEYIEA
GAKIIRTNTFASNTVCLGAGFDEVRNNIKNAVDIAREAVKGTDVLVAADIGPIPGENMIE
KEHIEKEYVDIVNVFKECGVDIFVFETFPELGFIDKAIENAGENGFVITQFAINQFGYSS
AGFSARKLIEEAGKNSYIDACGFNCGVGPGHMKKLVQSLINRNDKYFAVLPNAGYPQVVS
GRMVFDDNNAAYFSQIMHDLAEDGADIIGGCCGTTPEYIRQMVLKTADVVHMKNASIEEE
ISEKKTANDVSFYKGKEGRKLIAVELAPPLGIDDEKIMDAAFLMKESGVDVLTFPDSPSG
RTRADSILMAEKVSRETGMCVMPHICCRDKNAIAMRSQLLGAHINDINNFLVITGDPIPS
VVRASVKSVFNFDSVGLMNIISDMNQEQFAGKPVIYGGAINQGRVNFKVELERVKKKMEA
GATFFMTQPVFSDEDIDRLRQIKEQTGARILCGIMPFVSLRNATFMKNEMTGINVTDEIL
SRYRADMSKEEGEETGIQIAREIIAKTTDFVDGYYFSFPFNRVHMLKKIIGKNNQ
>A0A7Y5PWD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MHGRGKPVFSFEFFPPKSDEHVAPLLKTIAELKSALEPNFVSVTNGAGGSTRARTLQTVS
RVQLELGLTAMAHLTCSGVTQDDLCNEIGNLLGQGIENILALRGDPPKGDGAFKPVAGGF
AHASDLIEYLDSNYQVDIGAACYPEGHVESSNRDDDLRFTKLKVDSGALFLVTQLFFDNR
DYFAFVERARNARIRVPIVPGIMPITNVAQVERFTKMCGAKIPAELAERLRSAQDDPAAV
MAIGIEHAVLQCRTLLEGGAPGLHFYTLNKSFATRSVLAAVRRV
>A0A7C7R1Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MASNNGSAFRKAFETKDFVVTAEIGPPKGTDISRMVEHIEALKDVVDGLNVTDNQSSVMR
ISSLAVCRVILDHGGEPILQLTCRDRNRLALQSELLAAWILGVRNVLCLTGDYISVGDHP
QAKPVFDLDSVQLLQTVGMLNQGKDLAGNDLEGGTDFFAGAVVTPEADPIEPQMIKFQKK
IAAGARFFQTQAIYDVDNFKRFMERAEADGVKIMAGIVLLVSPGMAKYMNKNVPGIFVPD
ALIEEMAEAPKGKRLEAGIRIAGRMIRQLRDEKLCHGAHIMAIGKEECVPRILEAAE
>A0A3B8LV34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MLTLGEIYSGESTAISVEIFPPKTPDGDQALFDTLDRLAVFQPDFVSCTYGAGGSTRDRT
IELCREIQSRYRLAATAHLTCVGSTRDELVEWISRVQAAGIGNIMALRGDPPQGDETFAA
VAGGLEHANQLVELIRGVSSDLGVGVAGYPEVHPEAADATRDLENLKRKVDAGADAVFTQ
LFYVNDSFLWFRDRCRASGITVPVVPGIMPVTEFSRIQRIATLCGAKIPGELSDRLEAVQ
DDRDAQLAVGVEYAVEQCRELIDAGVPGIHFYALNRSQACARILEALGWNTSSESSGEW
>A0A2N7MT38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 10N.222.52.B12|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDATRDELIDIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A1I3JXK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. cf659|TrEMBL
MTDLTKPATADGQDGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYYEVGVRHIVALRGDPPG
GIGTPYSSHPDGYQSSADLVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARAFVTRAGTSVPDWL
AEKFEGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A3G8WJQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium breve|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQAVGEFNHASDLV
SYIRSVKPDLKVFGACYPEGHYQADTIDQDIENLKIKVDAGATHLISQLFYDNEDFYRFV
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A2D5M958|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MIEPDSSVSPTISFEFFPPSTPKGWANLDRRITELEPLEPSFVSVTYGAGGSMRERTHDL
VVRLLQETEIPAVPHLTCVGHTGAEIDGILDRYAMAGVETILALRGDAPRDGAGSERGEF
EFAADLVRHIQRFNDRNGSSFRIGVAGFPEGHPDTPNTLEGMAHLKAKVDAGADWICTQL
FFDNHAFLDWRDRCRLEGIDVPIIAGIMPISTRKSVVRMAGLAAGTVFPASLQRALGRAS
LDDEDAIAEVGLHWASEQCRDLLDHEVDGIHFYTLNKSDATLRIHRSLGVRTARSLRRAN
V
>A0A233HJ57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. V15_P4S5T153|TrEMBL
MGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSAQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASRDELIQIADDYWHNGIQNIVALRGD
IPAGGGKPEIYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQSDLVNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFN
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A3D2V2Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MPGLADLYKSDSAVLSFEVFPPKTEKGEAVLFQHMEKLVDHKPAYMTCTYGAGGTTQSKT
LEITSRIKQQFNIPVASHLTCVGATIDQLRQYLTDAERQQIDYIVALRGDPPQGSETFEA
VEGGFHHANELVSLINHEFPHYGVAVAGYPEKHREAPSMEVDLQNLKHKVECGADIVITQ
LFYKNENFFQFREACQRAGIDVPIIPGLLPVTNLAQIQRITSLCGAELPESFVQRL
>A0A1G8K6L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas panipatensis|TrEMBL
MSQERRYSFEFFPAKTEAGHEKLLATARQLASYKPDFFSCTYGAGGSTRDRTLSTVLQLD
GEVKVPTAPHLSCVGDSKADLRALLAQYKAAGIRRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGEHFHIEVAAYPEVHPQARNFEDDLANFARKAKAGANSAITQYFFNADSYFY
FVERAAKLGVEIPVVPGIMPITNYSKLARFSDACGADIPRWIRKQLEAYGDDISSIQAFG
EDVISDMCERLLAGGAPGLHFYTLNQAEPSLAIWKNLQLPR
>A0A2S6ISS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineococcus xinjiangensis|TrEMBL
MSVARLLTAGGRPTVSFELFPPRTPAATESLHRTVEALSGIGPDFLSVTYGASGSTRETS
RDLVRHVLSTTPVPVVAHLTCVGASRAQVIETATEFLDVGVRSFLALRGDPPAGRPDWQP
HPDGVARACDLVELLQVVERRHRAQRRPGRPVDDGPLSIAVAAFPAAAPAPSGPDDVEVL
LAKQRAGADFAITQVFYDARDYVRFADRARAAGVTIPLLPGIIPLTDPGRLLRLQGLTGV
PVPRELLARLESAADGGERAVHAEGIRASVELARRILDAGAPGLHVYTFNKHHAALDLLE
GVHLGGGAPTAPDLASRPWVSAPHHDMLRSAQH
>A0A4Q9R8H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas dryadis|TrEMBL
MSSPERRYSFEFFPTKTEAGHEKLLATARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDSKAELRELLNLYKDNGIQRIVALRGDLPSGMGMASGELRHANE
LVEFIRAETGEHFHIEIAAYPEMHPQARNFEDDIANFVRKARAGANSAITQYFFNADCYF
YFVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDVDSIQAY
GEQVISEMCERLLQGGAPGLHFYTLNQAAPSLAIWNNLQLPR
>A0A4R0NTS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacteraceae bacterium CFH 75059|TrEMBL
MLDRVREQRTAAEPSLFASLPGDISASFEFFPPKTERMEEQLWDAVLQVRDLRPAFVSVT
YGAGGSTRERTHNTVARIIAEAGLPAAAHLTCVDASRAETRAVAERYWSAGVRHIVALRG
DAGTPGAPFTPHPEGYASAEELVRGLLEVAPFEITVAAYPETHPDAVCARSDLDNLKRKI
DAGATRAITQFFFDAETFLRFRDKAEECCIGVPLIPGILPVTNVAQARRFAEQCGAHMPE
WLDGLFDGLDERPAARQLVAATVAAELCRKLYAGGVRQFHFYTLNRAELSYAICHMLGMR
PHGGRA
>A0A7S3PYI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetoceros debilis|TrEMBL
MPRIIDKINERRRKRHNRLHLQQQHDELHPNSTININDTSNNKNNNNNKNTKLNLPEGWY
YSFEFFPPKTEAGLDNLFTRIDRMSTRLDPLFVDVTWGESGSTSARSMAVASHAQHYCGV
DVLLHLTCTGMSVDQLEAVLRQAKSHGIQNILALRGDPPREKSSRGKGGRHWEPGDVSGG
ECPRAIDLVKLIRKLHGDYFCIAVAGHPEGHPSSNSVEEEMKHLRDKIDMDGDGGGADFI
ITQFFYDAKVFIHYVKCVRAAGITCPILPGILPIQSYNSFKRMTEFCGISVPRHVMERLE
PVKYDDEAVKKIGCEISKDIATEILTCCGKDDTGMDVDGIHFYTLNLERSVTRILLSMEA
VATRTVISPGSNSESNAFSNGTEDIEGQQRQQQNESNKEDTDAIATSPSRRQFPWRPSAM
ERRVKEDVRPINWANRPKSYVMRTDDWDEFPNGRWGDSTSPAFGELSELSHFYSFTLGSL
EDRLAMLGQNPKVSQDVYEVFAAYVEGKVPYLPWCETPLQPESFTIQKQLAALNRAGFLT
VNSQPPVNGVSSSHPIYGWGGSGGYVYQKAYCECFVSPENAQKLVSMVTDNQSMNLYAVN
NMGRELRVGLEEGGATALTWGVFPNREILQPTIFDPSTFLIWAEEAFSLWTNMWLNLYDY
GTDSHDLVESIRDTYYLVAIIDNDFVSQSSVGKLWEAFLKVGKVDV
>A0A6I7NC06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadaceae bacterium|TrEMBL
MTQNTHNAQVSFEFFPTKTDAGHAKLIAAAHVLAGENPEFFSVTYGAGGSTRDRTLNTVL
QLDQEVKVPTAPHLSCVGDSTDDLRSLLGQYREAGIKRIVALRGDLPSGMGQASGELRYA
NELVEFIRAETGDHFTIEVAAYPEAHPQARNFEQDLANFVRKAKAGADSAITQYFFNADC
YFHFVDRVRQAGVEIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSDSIA
AFGTEVITDMCQRLLDGGAPSLHFYTLNQAEPSLAVWRNLRG
>Q0FAR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium HTCC2255|TrEMBL
MSILNFSSNKVSEINPALEAFLKNFSIEVMPRTASKIENFKELLPQNTRVYIAHIEGTSI
NEMIDTAKRLTDEGYNVMPHFPARIIESKEVLVNWIDRYKNEAGVKDALLLAGGVNQPYG
EFHSSMDLLDTGEFDKAGFKNLHVAGHPEGNMDIDIDGKTKNVDSAISWKQEFSQKTDAN
MAITTQFCFESGPVIEWADRMASMGIDIPIHIGVAGPAKLQTMIKFSMACGVGASLRVLK
RRAKDVTKLLLPFKPDQFLTELAEYKALNPNFLITNVHFFPLGGIKTNAKWTIENGGISA
TPALQS
>A0A420HBM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysiphe neolycopersici|TrEMBL
MHISEKLAEAKKSGHPTISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGNVA
QLTVEMVGVAQSHYGLETCMHLTCTDMGKEKVDDALRGAFKAGCTNILALRGDPPRQQEK
WTATDSGFHYAKDLVTYIRQEYGDYFDIGVAGYPEGCDDQDDPELLLDHLKEKVDAGGTF
IVTQMFYDVDNFLEWVSKVRNKGISVPIIPGIMPINTYASFIRRANHMGCKIPPKWAKAL
EDIKNDDAAVRSIGTLLVAELCRKILASGLIHHLHFYTMNLAQATRMVLDELNLTPSEGR
PLKQPLPWRQSLSPRRRDEDVRPIFWKNRNKSYIMRTQDWDEFPNGRWGDSRSPAFGELD
AYGIGLKGSSEQYRKLWGQPTSIKDIAEIFVKYLQGDLDSFPWGDTPITSEADCIKTELI
DLNQRGFLTINSQPAIDGLKSSDLVFGWGPSNGYVYQKAYLEVLVPSELIDEIISRVSRD
SYLTYHAVNMSGNLKTNMPSDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEAYRLGLD
WARCYPASSPSCHLIENLMNNWYLVNIVHNDFHETLGLYRIFEGLKVSNFDHPFDASKFM
DKTINGHNFLNEQKTNGHSMQNGLKTNGNQNNNN
>A0A2R6AB59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marsarchaeota G1 archaeon OSP_D|TrEMBL
MRGSRSEESMKILYEVTPPSKRATRHELDYVVKNASSCGANEVDVTDSPTGESHSSSVAA
CVYIKTKYSLPVMCHIRTRDITLNALRAMVRACAVWEIEHILLVMGEGGENTGLTPTHAL
RVIREEKLLEGSTTKVGFVLQKGKSVEKKIRAKPDFLYTSPLTSVEELEWAVELSRSQNF
ELFPSLIVPSKKNEVILKRIGLQALSAERALTLATHALRLTSNLVVISPADPDEGFSFLK
RLNRNGL
>A0A839HQU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquariibacter albus|TrEMBL
MSSPPSEGRSLPLPVSFEFFPPNTEAGAEKLKTVVRELAPVSPEFFSVTYGAGGSTRERT
LSTVADIAALGYEAAPHLSCIGSTRENIAEILATYRKQGIRRIVALRGDLPSGTGTAGEF
RYASELIEFIRESEGPELKIEVAAYPEYHPQQRYARRDIDYFAQKVKAGATAAITQFFYN
ADAYFHFVEEARARGVDVPIVPGIMPFHNYARIAQFAQRDGIEIPRWVQLKMEGYMDDVA
SIRSFGLEVVTRLCERLLSHGVPALHFYTLNQSALSLEICKRLMR
>A0A800A416|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MNRNAPLAIASPLPNDVRVSFEFFPPNTEKANETLWNSIQRLSPLKPSYVSVTYGAGGST
RERTHAIVYRLRHETDLEPAAHLTCVGATTDEIDDIARSYWDAGVKHIVALRGDPTEGGG
PYQPHPGGYAYASDLVAGLKNIADFNISVAAYPETHPEATGAEADLDNLKR
>A0A519B9Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Acidulodesulfobacterium ferriphilum|TrEMBL
MMLTNFKSGNKLKESLNAGAFVYTSEISPERGTDLSKMKSIYELLKNRITAFNITDNQGA
NMKMSSLAGSIYIKQAGGEPIFQQTCRDRNRMALESDLLGAAAFQVKNVLALTGDHISFG
DHKHAKAVYDIDSANLIEIVKGLNAGADMNGNKLNDPTDFYIGAAVNPESVPLEPQLIKF
EKKITAGCDFFQTQAVFSVEKFNKFYDFYKNYKDIKIIAGIYILKSGKTARFMNQAIPGI
YIPETLIGELDNALNPVKKGVEIAARIARELKPLVHGIHIMAYGIEDKIPYFLDEFEKKG
SENS
>A0A2V7F8W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MRETLDRRIPSPRRVVARAPAPRPAPVEATGIARMLPPTPLARKLEAREFVVTVELDPPR
GHTVDKLVQGAKLLKEKGVEIVDINDGSLGRVRMSVLATALLIRDHTGLDINMHFTCRDR
NLMGIQADLLGAHALDIRNILAMTGDPPRTGDYANATAVFDVDGVGLIGILRRMNEGLDA
TGSSIGDPTAFCIGAALNPAAEDAEREIERMHRKIEAGARWLQTQPVYDLDALEGFLARA
GRIPVPVLVGILPLHSFRHAEFLHNEVPGITVPDAARARLRDAGDGALRAGIDMAQRLVA
EVRRRHAGAYLMPSFGRFEVVAEVLDALH
>A0A2V6U3N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MRVVLDRRRPGRPETKRPTLTVTPVAAGAEPGLRVAHPPTVLGRKLAAREFLVTVELDPP
RGHTVEKLVQGAKLLRERGVDIVDINDGSLGRVRMAVLPTALLVRDATGLDINMHFTCRD
RNLMGIQGDLLGAHALDVRNILAMTGDPPRAGDYSNATAVFDVDGVGLIEILRRMNEGQD
ATGSSIGEPTSFYVGAALNPAAEDVAREIDRFHRKVQAGARWVQTQPVYDLAELDRFLEQ
AGGSPVPVLVGILPLHSARHAEFLHNEVPGITIPEPIRRRLREAGDGALRAGIEMAQELV
RAVRQRYAGAYLMPSFGRFEVVAEVLDAIR
>A0A4R9BPF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Sr54|TrEMBL
MSACNARLAFSFEVYPPKTGAAASALTRTIDHLAAAGPEFISVTYGANGSSRNSSLDVLR
YIKDQTSADAMAHLTCVGSSHAEASRLIREFLDAGIRSFLAVRGDAPQGAAPDETTFLGD
LHSAGELVQLIHRVQTERVPYTETVIPGLPGARGVKTERSKVRIGVAAFPNGHPNSRSVS
QDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLFPILPGIMPVTSPNRLRRI
LQLSGEKLPAELSIELEVEPTEEGQRQIGIDYAVRLAQDVLAGGAPGLHLYAFNQHETVL
SILEGCGARSVPAAMP
>A0A3M8ELP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteiniphilum sp. X52|TrEMBL
MRVSELIKNTRNTAFSFELLPPLKGNSIQQVYNAIDRLKEFDPKYINITTHHSESIYKED
ENGAYRKVNVRRRPGSVAIAAAIQNKYGIRAVPHIISQGFSKEETEYALIDLSFLGVTDL
LLLRGDTKKLDAEQRKMDCHPYATGLQEQVNNFNKGVTFDGSSFTPPEESFSYGMACYPE
KHEESPNMESEIYYTKMKVDNGAEYLVTQMFFDNSKYFDFVKRCRDVGITVPIIPGIKPI
HMKNQLTVLPRIFRTDIPEELATALRKCKNDEDAKQVGVEWCVEQCKELIRNNVPSIHFY
SLMATESVRRVAGEIY
>A0A257IS34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagaceae bacterium BCCC1|TrEMBL
MPKVVEHLAKVNDKPVFSIEIIPPAKGGKIDELLNDIAPMMEIKPPFIDVTYHREEYISV
KSEDGSTKEIKTRKRPGTVGICSAIMHKFDVDAVPHVLCGGFTKDDTEDLLIDLNYLGIE
NVMALRGDHAKPFSTFKPKTDGHAFAAELITQIKDMNHGKYLHEDSEYLSKSNFCIGAAA
YPEKHFEAESHEIDFTHLKAKVDTGAEYLVTQMFFDNQKYFDFVNKCRENNIHIPIIPGL
KILSTKKQLDILPKLFYLEMPSEFDKAVRQAKDDKDARKIGIEWCITQCRELIKFGVPAL
HFYTMSKSTTTMAVAKEIF
>A0A2S3W2F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novacetimonas maltaceti|TrEMBL
MHVSVELIPRDTETLLRDAAEVRSCFPLADMINIPDLLRFPLRSWDAAALVRPHFPNVIP
HIRAIDIAPDAPLPGVGQEGLEAVLVVQGDPPSDLRHLTYPNTTESIIRRYRAEAPHLSV
YAAFDPYRRAPYEEMEAIARKKEAGAAGFFTQPIFDMRMLDLCMNWLHGENVFWGISPVV
GPRSRSYWETTNHVIFPHDFEPTMEANIAFARQMMHAVRAQGGNVYLMPLRVNLQRYLVP
LCDV
>A0A7Y0RAY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter orientalis|TrEMBL
METQKQFRRRFSFEFFPPKTDRGWEKLQGVRNTLAGVDPDFFSVTFGAGGSTRDRTVQTV
LDLHKRGVSTAPHLSCVGASRGSIAELLDVYRDNGINRIVALRGDMPSGMGAAGELRHAN
ELVSFIREHSGDTFNIEVAAYPEFHPQARTAEDDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLERMGVTIPVVPGIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSDSIRQ
FGEEMVTGMCEKLLAAGAPGLHFYTLNQAEPSLSIWKNLGLGERQKIAF
>A0A7K6VVH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Notiomystis cincta|TrEMBL
MVNETQHPCSASSSSRSDGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQEAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCSNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPR
>A0A8B9TWZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anas zonorhyncha|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYESDLKHLKEKVLAGADFIITQLFFRSETFIK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYISGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A7V9ZHA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriales bacterium|TrEMBL
MTIPCSFEFFPPKDQEGERKLWEAIRRLEPLKPNFVSVTYGAGGSTRDRTLRITAQIATD
TTLTPVAHLTCVGHTRGELRAIVAGYLESGVRHVLALRGDPPGRGEWVPTPQGVDRACDL
VRLVMEVGDFEVGVAAFPEGRPGVWDVKAEADLLVKKEEAGASFAVTQMFFRAADYFRLV
ERVRSRGSELNIIPGVMPITNAAQITKFAELSGCSIPDDIARRIANCSADDDVKREGVQI
ATDLCQQLIDGGASSLHFYTLNQSKATTQIYRLLTDA
>A0A813PYF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Didymodactylos carnosus|TrEMBL
MKPEGGNIQTGNMYGNGIDIDGCNNSDNGQLDITLRSPVSPKGSCSLQSHQYVRLTDQIR
KRISNNERWCSLEFFPPRTPSGAANLIGCFDRMAIGQPLFCDITWHPAGDPAGDKETSSM
MIANTMLNYCGIDTMLHITCYGARKESMMEYLKKAKDFGIRNILALRGDPPLGEEWDPKK
TDFRYGVDLVKFIRQHFQDYFVICVAGYPQGHPEGSYDDDLRYLKEKVECGADFVITQLF
FKAETFLKFEADCRAIGIKCPIIPGIFPIQGYSSLRNIVRLAKLDVPKEIVECMEPIKDN
DEAIRNFGVHACLQLCTSLLDSGIVNGLHFYTLNREYATIQVLKQLGLWMEEPPLRALPW
KKTTANYTRSKENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGVMTDYHLFYL
KIDATKDELLEEWGRELTSEQDVWKMFACYIGGEKNQNNKIIKHFPWTDEELSLETKLIQ
NNLVEYNRRGILTINSQPAVNGSPSTDPVVGWDKSAKWICAYLEFFTSAKNIPALREVLR
KFPSVNYHFVNKSGNDNEANADDEQPIAVTWGCFPGKEIIQPTVVDSISFMIWKDEAFGL
WNERWAKLYEPETKSHEIIETVANNYYLVNLVDNDYVKGSCLWAVLDAMFEYQKSEENLT
SSIVS
>A0A803M2V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chenopodium quinoa|TrEMBL
MKVIDMIKAAEAENNTMFSLEFYVPKNEDGVVNLSKSMENLVAHSPCFCDITWRATQGPL
TLEIANLMQNSVSVETMMHLTCINMPVQKIDDALDTIKSFGLQNVLALRGDPPRAQEQLR
GDGFSSALELVHHVRSKYGDYFGITVAGYPEAHPDVIGADGLVSPESYANDLAYLKTKVD
AGADLIITQLFYDTDVFLKFIPQAIIDALEPIKDNDEAVRAYGIHLGTEMCNKIVASGIK
QLHFYTMNVDKSALGILMNLGLIQMSIIQRPPWKCSAIASSTEEDVGHGRRADVHNAFYL
QVRQISVAILPKLAYMTCTY
>A0A6H3ASR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. A316|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A3E2XQN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus catus|TrEMBL
MDIREYLANNRLITDGAMGTWYDRLTGYKGKLAERANLDDLQQIRDIHRAYIEAGARLIR
TNTFAVNSMFFSADEIAAVLKAAWENACQAVSDSGRDVWIAADMGPIDENETKSAADVEN
EYIHLADCFLGLGAKIFVFETLSEFRSVKKAIAYIKAECPDAFIVTQFSFNRNGYTRSGL
SVRALLLEAAAMKELDAVGFNCGVGPLHLYELLKNQRFPEGKYMTVLPNAGYPTELRGRT
FYSENVPYYVDMMGRIAALGFDIIGGCCGTTPEHIRGLHDLLVNDVRPPKKLMPAVYSAD
GKENCAEEAVEEKTDFIQKLERGEKVFVVELDPPFDVNDTKLMEGAALLRDINVDMITLA
DSPLARPRADSIASAIKMRYTRQMEAMPHICCRDKNMIAHRSQLLGMQMNGLRHALIVTG
DPIARGDRESIKSVFNFNSIKLMKYIQTMNQEVFGSRPIYYGGALNHNNGSIDNIAARMC
QKMEAGAQWFLTQPVYGQEDIDRLKELKEKSGGRIIAGIMPLVSRKNALFIKNEMPGIHV
PDQVLERYEAGMSREAYEDVAEAISVDLMKRLEDVCDGYYMMTPFNRAALIKRIILQAKK
ELR
>A0A803KZ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chenopodium quinoa|TrEMBL
MKVIDKIKAAESENNTIFSFEFYVPKNEDGVVNLSKSMENLVVHSPSFCDITWRATQGPL
TLEIANLMQNLVSVETMMHLTCINMPLQNIDHALDTIKSFGLQNVLALRGDPPRAQEQLR
VDGFSSALELVHHVRSKYGDYFGITVAGYPEAHPDVIGADGLVSTESYANDLAYLKTKVD
AGADVIITQLFYDTDVYLKFVNNCRQIGITCPIVPGIMPILSYKRFLGTTRLCKTKIPQA
IIDALEPIKDNDEAVRAYGIHLGTEMCKKILASGIKQLHFYTMNVDKSALGILMNLGLIE
ESKIQRPPWKCSAIASSTEEDVGHGQRADAHNAFYLQVIIGPQIHHNQRVLEWGEGYYNG
HIKTRKSVHNKDVDNHKLGLERSEQLRKLYEALLEGESEQGAKKLSLALSLEDLSDLEWY
YLVSMSFTFKVGQSLPGRALATGQHIWLYDTQSADSKLFTRSLLAKTVVCFPHKGGVIEL
GVTDLVLEDISFIQHIKTALVQPIEPDCSPKASSVSQKEDSDKDHVIANITENEDEMVDI
LPFSSLHNSAEQIKFDEDIENGLYQSVLEEFIGSPGDCSNDSSHHAEESFYSCTSTFMPW
KKELTADNFRMQESQNTLKKVLFRVPLIKTNRSNSGRVNEDEMQDYPMSPQTYDVYKLDF
ALQETTANLLLSELEEKKDNPLYMVQESMIPSITEMDEAFILTDSTKYLAGVEELETSID
LEGTGTAKDLDMLEQNQQAYDIYSKSMASEINEIDPNSNKAIQTEILQPLDIDIEVSIEE
LEVLITMKCPWRECLLIRIMEVLSNLNLETHSVQSSTLNGILSVFLKSKV
>A0A009F8V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 348935|TrEMBL
MEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTFPSSVEKIIHYSGKGRD
ITDFETFLKLTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLESVNAVMAAKCYGGFHI
GVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALKQAKAFLNRHRYPQNIL
ACVMPLSLARASFMVKHKIAGIVITPHMLRVLAQEKQDGRTENAYKRCAIQILMCKYLGF
AGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVETKKEFVPELAYYSRQPS
SSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKALLKTEFISKQGVVGCE
SCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVGQTDVL
KEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A2T0CBQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pumilus|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVRRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYTIEEIKR
SFREQLYILLNEQPDGLLLETYYDMEEAKAVLQIARKETTLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPILENSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHIHAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELATKKRTIIVELDPPKKLNFEKFLVAANELKNAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMAKAGEDKEKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKESNTHVNYH
>A0A672ZJD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaeramia orbicularis|TrEMBL
MVNQVPRGDGSWQSFKSDSSGASTSGGDSSKDSSRCSTPVLEADRSDRLRDKMRRRTESG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTTHKITGYLEKAKRLGLKNIMALRGDPVGADWEEEEEGFNYAI
DLVKHIRSEFDDYFDICVAGYPTGHPEAGSYEEDLQHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIQQAVQMCRVLLDSGKVSGLHFYTLNREVATMEVLRQLGLWTEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSTKDA
LLQMWGDELMNEQSVYEVFTCYITAQPNHRGHKVMCLPWNDEPLAPETNLLKEELEKVNR
RGVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRV
NYHIVNVHGQNRTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWG
KLYEEESPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQVIDDMFELLDTPPDPLSDGTAS
E
>A0A7W5XI57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK650|TrEMBL
MTQKNDVRRRDIVFSFEFFPPKSEEMEGQLWNTVRDLQDWNPEFVSVTYGAGGTTKAPTL
STVTRFLTDTPLATASHLTCVSATKEETHQVVDSFRKAGVTHFVALRGDAPGGVGAPYQP
HPGGYANAAELVAGLKQIGDFEISVSAYPEKHPESRDQAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGVGIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGYDD
KPEERAKIAADVAAEQIEDLVRRGLHEFHLYTMNRAPLVSAVLENLGFSRHAARNAGAAA
>X2JVA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aggregatibacter actinomycetemcomitans HK1651|TrEMBL
MSYAKEIDNLNQHLADLNGKINVSFEFFPPKSEKMENLLWESIHRLKVLKPKFVSVTYGA
NSGERERTHGVVKRIKQETGLEAAPHLTGIDATSDELRRIAKGYWDSGIRRIVALRGDEP
KGYEKKPFYAADLVALLRDVSDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPAWMSKMYEGL
DDDQTTRNLVAASIAMDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGIRPSL
>A0A520D9G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp|TrEMBL
MRLPLSFEFFPTKTAEGAAKLRAVRRQLYALKPEFCSVTYGAGGSTHQGTFDAVREIVAE
DVPAASHYSCIGATRATVRAQLAELKAMGVHRLVALRGDLPSGYGIGGEFQYASDLVTFI
REETGRDFHVEVACYPEIHPQARSPEADLRAFALKMKAGADSAITQYFFSAEAYFRFVDD
ARKLGVDAPIVPGVMPITSSTQLLRFSDACGAEIPRWIRLRLQAYGDDLESIRAFGLDVV
TGLCEKLRDGGAPALHFYTMNQAAAPLAVLDRLGWNA
>A0A2T6ZAF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tuber borchii|TrEMBL
MVHIAPKLMAEHTKNGKPTFSFEYFVPKTAQGVQNLYDRMDRMNQLGPQFIDITWNAGGR
LSNLTCEMVNVAQSVYGIETCMHLTCTGMPRSKVDNALKEAYKAGCTNILALRGDPPREN
EKWEADPHGFRYAKDLVKYIKANYGDHFDIHVAGYPEGCDDGTDPELLLEHLKEKVDAGA
SSIITQMFYDVDIFLDWVKKCRDIGITVPIIPGIMPIHTYAAFMRRATWTKCHIPKKWLD
RLEPVKNDDVAVRDIGKELMVELCQKIIDAGILHLHFYTMNLATATRMCLEGLGIIPSLE
ERTKALPFRPSLGLNRKEENVRPIFWKNRHMSYVQRTQEWDEFPNGRWGDSRSPAFGELD
AYGIGLRGSNEANIKIYGYPETIRDLGELVKQYLTGNLPSLPWSEGYINSEADVIRDELL
KLNGRGFLTINSQPAVNGVKSTHPVYGWGPKNGYVYQKSYLELLVSPEHLTELVTRIERN
PDLSYHAVDKHGTLKTNAHEGPNAVTWGVYPGKEIIQPTIVETISFLAWKDEAFRLGDDW
AKCYEAGSASRHLIQEVMDTWFLVNIVDNDFHQSEKIYRLFDGMGVPDVDEKP
>A0A1C4GVC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter albensis|TrEMBL
MTKRVPFSFEFFPTKTDIGAEKLRVVHQELQLLKPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFKIEVAAYPEMHPQAETFDKDIQHFVEKVKAGANAAITQFFFNPDAYFYFI
DRLAKQAIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVLKLSERLIAGGAPSLHFYTMNHTEPNRQLILDLGLA
>A0A6C1N990|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonadaceae bacterium|TrEMBL
MKTQKAYPRRFSFEFFPPKTDRGEEKLQLTRDRLAEHDPHFFSVTFGAGGSTRDRTLKTV
LDLNSQGVSTAPHLSCIGASKADVAELLDIYRDNGVDRIVALRGDIPSGTGSSGGGELRY
ANELVSFIREHSGDHFHLEVAAYPEFHPQASNAEQDLRNFKRKVEAGADSAITQYFYNVE
SYFYFLDRMEKMGLDLPVVPGIMPIVNFSNLVRFSDMCGADIPRWIRKQLEAYGDDSSSI
QKFGEEVVTRMCQQLLDAGAPGLHFYTMNQADASLNIWHNLSR
>A0A2N3YFG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycicoccus duodecadis|TrEMBL
MVRMVAPQSLRRRGSRTLGAMAQYGGGGRPEHLVASIPARLRDERPSISFEFFPPKDDAS
EAQLWDALRRLERVRPAFVSVTYGAGGTTQDRTVRVTGRIADETSLTPLAHLTCVGASVR
QLRQVVGHYAASGVRNILALRGDPPGNVRGEWTAHPEGLDHAEDLVRLVRGLGDFTIGVA
AFPDVHPDSPDLDHDVEVLVRKADAGATFAITQMVFDADSYLRLRDRVAARRDLPVTPGL
MPVTSFPQIQRMSELMGTPLPPQVVERLEAVKDDKVAVRAVGVEIATEIGRRMLAEGAPG
LHFITMNRSTATLEVHEALGL
>A0A370BNJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus niger ATCC 13496|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDGQDPARDLPFL
IEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPHVLSKLEEVKHDDDAVKRIGVDIISDLVHGIRDLVSPGLRGFHFYTLNLEKT
VSFILERCELIPPYTEIDDSDALADGGNLSALDSSSYIAPNGAPIRTLASRRSSVSSIPH
NRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEEDSNGLNAETAIIQPELLTLIDKKGWWTLASQPAINGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNTDDPDPIDIN
PANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDDTK
NDVWLVCVVGQEFGAGTEPGSEEEEDEKKWMWRELANSQ
>A0A2Z3H6A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmata obscuriglobus|TrEMBL
MHIQDIFAQHRTTFSFEFFPPKTDAAGEELFTTIAALQTLHPSFVSVTYGAGGSTRDRTH
DLVVRIERETNLTAVSHLTCVCHSRDEMIAILDRYATSGIENILALGGDPPKNSAHDREK
DAFRYANELVDFIRSRPGPNGRGFGVGVAGFPEGHPGCPNRLQEMDHLKRKIDAGADYIC
TQLFFDNRDLYDFRERCDLAGIKVPIIAGIMPVTTKAGMVRMADLAAGARIPAKLLKAVS
RCADDTAVARVGISWATEQCADLLHNNIRGIHFYTLNKSDATRLIYQNLGVESSVALRAG
>A0A1H1T2B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas asplenii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASHNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKIPSAPHLSCVGDSKDDLRGLLTQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDIQHFVRKANAGADSAITQYFFNADSYFY
FVDRVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQAFG
EQVVTEMSERLLQGGAPGLHFYTLNLAEPSLAVWNNLKLPR
>A0A0A2B3G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus str. SB|TrEMBL
MKSKLQQTLEKRSKVITAELMPPRGGSPVRSLKIAQLLKDKVHAVNITDGSRAVMRMCSL
AMSKLLLENGIEPVMQISCRDRNKIALQSDILGANALGIRNILCITGDSIKAGDQQDAKA
VHEFESVRLLQQIQAFNKGIDPTLGELSDKKTFIFAGSAADPNCRNKRSLENRMKKKKEA
GAGFIQTQMVMEKENLIEFCEKISKPLEIPVIAGVFLLKSYKNALFINKYVPGAYIPENI
LNRLKDAKEPLQEGIKIAAEQAHDFMNIANGVHLMAVKAEHLIPEIIEKANLSLEY
>A0A2I0S506|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cercospora zeina|TrEMBL
MHITEKLQQAHGKGKATCSFEYFPPKTAQGVQNLYDRMDMMHGLGPAFIDITWGAGGRHS
SLTCEMVKVAQTAYGLETCMHLTCTDMERSKIDDALKEAYKAGCTNILALRGDPPREQEK
WEATEGGFRYAKDLITYIKKTYGNHFDIGVAGYPEGVDETCGADEHILYLKEKIEAGGTF
VVTQMCYDADIFIDWVKKCRAAGIPESVPIIPGIMPISTYAAFLRRANWTKAHIPEHWLE
KLEPIKNDDSAVRAVGCDLIVEFCQRLLDFGLMHLHFYTMNLAQAVKMVLEKLDMIPEAE
SPHPDIKPLPWRQSLGLNRREENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
GLDEYGIGLKGTNEHNRKIWGEPKSIQDIAQLFVGYMSGSVESLPWSEAPINDEANTLVN
DLVQLNSRGLLTINSQPAVDGVKSSHPTYGWGPRNGYVYQKQYLEVLVSPALIDIVIARM
DRDPEITYYAVNCNGELKTNAHPDGGPNAVTWGVFPGKEIVQPTIVEMVSFLAWRDEFYH
LGLEWSKCYEEGSESRKIIREVTQNWYLVNIVHNDFRQQQGIFPIFDGLKAPGLEPAEVN
GVNGHAETNGVPPETNGVLDGNNTVNGADKVASSNSAQTA
>A0A0F6AKL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga sp. (strain RQ2)|TrEMBL
MRKSLEIGKCVVLEVLTPRGTNLGRFMEFTEEAWKTGIDAFTVTDMPMGRVRMAPWAASH
LLVESGKDVLMHFTRNTRNMIRIQSDLLGCHALGVKNLLLLSGDNPSHGDYPETTSVNDI
DILDLIRLTKLMNEGTDLAGNKIYGKTDFFVGGALNPFSDKDIKRAKQKIEAGVDFLVTQ
PLFNSEVAKKIKEELNTKILASIVFFENAKQMSYFSNVPGIEIPDEIVNSAEKGDDYLKE
KSFESVLRFVEETKGVLDGFYIVAIVKDLEKIRKVVEIAKS
>A0A3S9A8R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus albus|TrEMBL
MKPDFREALAKRILTGDGAMGTYLYGMGFPVGVSYEEFNLIRPHVIEDVHRRYYEAGARV
IETNTFSANLASLSHYGLDSEVEAINRAGVRIARAAVGADAYVVGAVGSIRAGKRKNISE
AQLEQLFRQQMDALLQEGADGLLLETFYDLEEALLALRIARSLSDLPVITQFAVEKDAVT
QDGVPLASAFEQLKQAGADVVGFNCRSGPNGILRAIDAIVGDIPLPLSVFPNAGIPDYVD
GKYSFTASPEYFAESAKKFADRGARIIGGCCGTTPEHIAAIAAALNGYTPQQTTDTRETA
PAVQTETIQIKESFTPPAQTEPNIVDLVKERHTVIVELDPPRDLDIQKFMAGAKALAEVK
ADAVTMADNSLAVTRMSNIALAALVGQQAGIRPLVHIACRDRNLIGTQSHMMGLDALGID
HVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGIAFSGKPLKQKAKFVTGAAFN
PNVKYLDKAIQRLEKKIESGADYIMTQPVYDKELIIRVAEATKHLSVPVFIGIMPLASGR
NAEYLHNEVPGIQLSDEVRKRMAGLEGETGRAEGVRIAEELLDTALEHFNGIYLITPFMF
YEMTVKLTDYVWRKTSKLTR
>A0A832WL75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrococcus horikoshii|TrEMBL
MRILSCPKKLLNGPCGDVFNGTCRVSKKPCPWVYVLEKLDTLDGAPLLVEHPIVARFTLE
DDVEIKKSKFIKDLEKGRAISVEFPIRVFESGFKDFKDNGYLFTVPDNPLGYPHVSSVAL
ATWLKSKGFEVMPHVTGKDRNALAITSELRTAVEFNFEGVLLTTGDWPGLMLHAKPVFDL
DSTNMIKLARLVFSGILPTGEKIEVKERPFVAGTMNPNYQEKLEGKRLARKIIAGVDVVF
TQVVANVKVARKIPEIVKHSLKYSSREVPIVVSLLYPIKKELENALRSMGVEVGSKFEEV
LEEVSSLEFAGINLIVFADDWMEKVEEALELVKEVV
>A0A8J8HGK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoactinospora sp|TrEMBL
MALGRPSILPDRVPTVRELLAAGGRSFSFEFFPPKTDEGERQLWKAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVR
GDPPGDPGAEWVRHPEGVLYAEELVRLIRQAGEFCVGVAAFPYKHPRSPSIESDTEFFVR
KCRAGADYAITQMFFQADDYLRLRDRVAAQGCETPIIPCIMPVTQMSTIARSEQLSGAPF
PADVAARFEAVADDPAAVRALGIDHGAELCQRLLDEGAPGIHFITFNRSSASREVFQRLT
SVAATA
>A0A7W2UHW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. GMR22|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSRAELRNIIGQYAGAGIRNMLALR
GDPPGDPLGEWVQHPDGLTYAADLVQLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATKLCARLMAEEIPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A7Y4N896|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcus xanthus|TrEMBL
MKIRNRLNPSDPCFSFEFFPPRTDEGEANLLKALEDLATLQPGFVSVTEGAGGSTRAKTV
ELVLRIKQEAGIEAMAHLTCGGHSPAELRTVLERLSAAKVDNVLVLRGDPPKGQTLFEPA
PGGFRYASEMVRFIREEDFNFCLGGACYPEGHVETPSRDDDLRHLKAKVDAGLDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQIQRFTRLCGATVPMRLALQLERVKD
NPEAMAQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRARS
>A0A7Z6U986|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. actinidiae|TrEMBL
MGSMSQDRRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVL
QLENEVKVPAAPHLSCVGDSKEDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHA
NDLVKFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADS
YFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQ
AFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A854EJE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces naeslundii|TrEMBL
MLDNEPTESASVPGSSGDDAGSARREAGRSLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTEPVPGTGRRSGADQECLPRVRVVQEETNPSEGVLAHVLESSTIPL
MAHLTCIGYCKQEAVDIVTRFLRMGVRRFLALRGDPPAGARADEVAGELRHADDLVRVIR
EVEADFFGDGKRHVTIAVAAYPATNDHIEAIEVLAAKQAAGADLAITQVFYDPADYVALT
NAASYAGVSIPILPGVIPLTDLRRLARLEALTGVRVPDALRSSLGSASGATLVERGIGAT
LDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDAVDRGYLQAT
PGRGPSFLRSGSPGAAASPRHPVQPHNTITKENA
>A0A7U9QG35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O145:H28|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPLGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A845RSJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. 4CP|TrEMBL
MENAFRKAIQDNNEFIVTWELVPGRGSKEVSQEKALQLAEQAAKGKKIHAVSLTDNPGGS
VGINPEGIGREIKSLGIDAIIHVACKDKNRTQLESQLFSLERSGLHNLLVLTGDYDPGNF
FGRPKPVFDLDSTQLLAFITKMNDGLELPTVRGVNKLQPTHLFAGAAVSPFKATEAEQML
QYTKLKKKIENGAQFIIPQVGYDVRKYHELYQFVKHNNLPGCLMGNIYLLTYGAAKAMSM
NKVPGCVVTDKLVAELEQEKQSSDKGVAAMLDRAAKLFAILKGMGYKGVHLGGHNTTYEQ
VEYIIDRGNELTANWQDYIREFDYPQKNGFYVYAKDEKTGLNTAQKSNDYNNYEKSFDLN
YKMSRVVHKMMFEPNKGMFGFMRGFCHAIKDSALEKPFHGIEHLAKSCMYNCQDCGDCAL
IDVAYVCPMGNCPKNQRNGPCEGSYNGWCEVYPDKQKCIWVKAYYRLKGYSEEEKLNSYH
VSPYNWEKQHTSGWINFFEGQDHSAERLGIKPRTKSKEKE
>A0A7J9UYD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Georgenia ruanii|TrEMBL
MSVATHPTVSFELFPPRRPELDETVWQRVLRMAEAGPDFFSVTYSVSEAARAASAELLRR
LLVQTRIPPIAHLTCVAATREQIAARVRRLLDAGVRDFLALRGDPPPGETTWHPPPDGLS
RSSELVALIREVEAERREDGCLRAAAPSVVALDLGVAPADVVSVAVAAYPSGQSHTRTAE
LAALREKQDAGADFAITQVFYDAEAYASLCADAGTAGVHIPILPGILPLTDRRRLHRLDE
LSGVPVPVTLDALLDTPDDTERLRRGIDATLALIDRVLAVGAPGLHLYTFNQDRPALDVL
EHLRARGVRNPALETRPAVPPART
>E8LRY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio brasiliensis LMG 20546|TrEMBL
MGYTHASHIDALNQNVAELSDNINVSFEFFPPSNEKMEETLWNSVHRLKNLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDASREELIQIADDYWANGIQNIVALRGD
IPPGGGKPEMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNAVKVPGWMAKQFE
GLDDDPTTRQLVGASHAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQG
>A0A7Z6UJX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. actinidiae|TrEMBL
MGSMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVL
QLENEVKVPAAPHLSCVGDSKEDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHA
NDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADS
YFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQ
AFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A2N2PWX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-1|TrEMBL
MAVRRVGAPSTDSTVRPGGLRAERADHPASGGSGQEAGVQLPVVRAVHFTLLGAAANPFA
PPFDYRPLRLGKKVAAGARFVQTQLIYNLERFKTYMARVRDLGLHERVYILAGVGSLKSV
GAARSMADKAGGSGGNMLVKDQMTPHPVCGRPEMPVTEAQALMQEHSIRHLPILDADGAL
VGLITQRALTQAVPSDVKKFSPFVINYVLAKIKARNIMVKDVITIGEDMAIEEAARIMAD
RKIGCLPVMRDGELVGIISDNDLFNAMVNLLGARRAGLRVTVLQPDRAGEVARISTAIAE
KGGYLSGFVTYPTADPSIWASLFKVTNVPKEKLIETLNNLPDIRVQDVRDV
>A0A014BU34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_4|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A1Q8XL57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces naeslundii|TrEMBL
MLDNEPTESASVPGSSGDDSGSARREAERSLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTEPVPGTCRRDGVAQECLPRVRVVQEEANPSEGVLAHVLESSTIPL
MAHLTCIGYCKQEAVDIVTRFLRMGVRRFLALRGDPPAGARADEVAGELRHADDLVRVIR
EVEADFFGDGKRHVTIAVAAYPATNDHIEAIEVLAAKQTAGADLAITQVFYDPADYVALT
NAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVKVPDALRSSLGSASGATLVERGIGAT
LDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDAVDRGYLQAT
PGRGPSFLRSGFPGAAASPRHPVQPHNTITKENA
>A8YD20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa PCC 7806|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>A0A5D0XQB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter echini|TrEMBL
MTPRTYPALSYELYPPRNAKAVGPLWATIRRLEATRPDFVSVTYGAAGSNREAAIDLLRR
LLTETTLKPLAHLTSVGSSRAELVGIIERLLGGGVRGILALRGDAPDGVEPGSGDVEHAD
ELVRLIRDVEAQRTAQLAAGRVSIGVAAYATRHPDSPSIERDIEVLLAKEAVGADFAITQ
VFFHASDYSKLVSRAERAGVTIPIIPGVMPMTSSRRLTKLGSLAGIDVDDAFRARLDDAA
SDEERRSIGVAATVELARAALDEGAPGVHLYTFNEHAAALAVLDALELERPPEAGLAASM
>A0A0V0ILJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solanum chacoense|TrEMBL
MRAKYGDYFGITVAGYPEAHPDVIPSTGLATLETYENELAYLKQKVDAGADLIVTQLFYD
TDNFLKFVSDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTRIPAEITAALEPIKDNEE
AVKAYGIHLGTEMCKKIMASGIKTLHLYTLNMEKSALAILMNLGLIEESKISRPLPWRRP
TNVFRIKEDVRPIFWANRPKSYISRTIGWDEFPHGRWGNAKNPSYGALGDYQFMRARSRD
KKLQEEWAIALNSVEDIYERFMNYCLGKLRSCPWSELDGLQTETKIIDDHLGNINSKGFL
TINSQPAVNGAKSDAPLVGWGGPGGFVYQKAYLEFFCSREKLNAVIEKCTAFPFLTYMAV
NKKGNWMSNVNQIDVNAVTWGVFPAKEIVQPTVVDPASFMVWKDEAFEIWSRGWAQLYPE
NDPSRTLLEQVQNSYFLVSLVDNDYINGDLFAIFKDMIWN
>A0A014CU96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_3|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A347UMQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio alfacsensis|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLNPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDATRDELINIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAGA
>A0A0R1MKZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus hordei DSM 19519|TrEMBL
MTTFNYSLELLQNSSISELATLQKLDPEFISITYTNHALSFFETTFTTALTLRKTTHIKT
VIHLPATSFTKKELTTLLAELDCSPIDSVLVLSGDQKINKKSIYTSALELTRFLSNELPH
LNILCSCHPETITSKVDLQKEIDLMKAKESAGCKIFISQIFFDNTSFVKFVKYCRAAGIK
AQIRAGIMPIINKNQVSFVEKVLKIHLPHSFKNIENNTDLRKVGIQFALSQIKILKDKGI
ANFHFFTMNDLETIKILTDGVL
>C6XMD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hirschia baltica (strain ATCC 49814 / DSM 5838 / IFAM 1418)|TrEMBL
MSNLNISFEFFPPKSDAVENRLWDSVHRLSPLQPKFVSVTYGAGGSTRERTLDVVGKIAA
DTSHSIKAAGHITCVAASKAEVNEVLQSYWERGVTSIVALRGDPAEGIGAKYTPHEDGYA
YASDLIQGAREIADFDISVGCYPESHPEARSLQDELTNLKRKFDAGADRAITQFFFEPET
FLRFRDKAEAAGMDKPIVPGIMLQSNFKGLARMAEMCGAYLPPKYAELYEGLDDDLETRD
LVTAHLTAELCNKLVDEGVKDFHFYTMNRAGLSLATCRLLGVKPSKGISA
>A0A6J1DPD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Momordica charantia|TrEMBL
MKVIEKIRAATAGDGGRVVFSFEYFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGS
TADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQ
DKFVQIEGGFACALDLVKHIREKYGDYFGITVAGYPEAHPDVIGSNGVATPEGYQSDLAY
LKKKFDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCK
TKIPDEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHVYTLNMEKSALAILM
NLGLIEESKVARSLPWRRPTNVFRIREDVRPIFWANRPKSYISRTIGWDQYPHGRWSDSS
NPSYGALTDYQFMRPRARDKKLLEEWALPLKSIEDVYEKFMKYCLGKLRSSPWSELDGLQ
AETRIISEQLGKINMKGFLSINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSREN
LDALVDKCRVLPNLTYMAVNKEGIWVSNITQKDVNAVTWGVFPAKEIIQPTVVDPASFHV
WKDEAFEIWLRGWASLYPEGDLSRKLLEEVQSSYYLVSLVDNDYVHSNLFAILEDF
>A0A5M7CF39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora hirsuta|TrEMBL
MTKVIDRLRPGKTVFSVEFFPPKTDEEERHLWRAIRELEPLDPAYVSVTYGAGGSSRDRT
VRTTGRIASDTTLVPVAHLTGVNHSIAELRHVIGSYAAEGITNVLAIRGDPPGDPLGEWI
PHPEGITYADELVRLVRECGDFSVGVAAFPHMHPRSPDLESDIKHMVNKLRAGADFSVAQ
MFLEPEYFLRLRDRLAQRGCHQPLLPGIMPITTPKVLGMTTQLSNMTIPDEVSAVLDPLR
EDPAGFREAGLEITTRLCEKLIAEGVPALHFYSLNRAKATREVLANLGLIDGVLKAA
>S7IX12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera sp. NM10|TrEMBL
MHTNELFAKKTVFSFEVFPPKRDIPVETVYPTLDELSQLHPDFISVTCGAGGTGGNRTVE
VATYIKQLGCETAAHMPCIYLTEEAALQNLKELKEAGIENILALRGDEVPGRERAHVFEH
ASDLVAFIKEKEPDFNVIGACYPEGHTEAKTLAADIRNLKTKVDAGASELISQLFFDNAL
FYRFLERCEIAGINVPIEAGIMPVTNKAQIERMVTMCGATLPIKFQRAIAKYGDTPESMR
DIGIAYAVDQIADLLANGVDGIHVYTMNNPYIAKKIAEAVKTLL
>A0A377H689|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallibacterium anatis|TrEMBL
MSYAKEIDVLNRSIADLNGDINVSFEFFPPKNEKMETLLWDSIQRLKSLQPKFVSVTYGA
NSGERERTHSVVKTIKQQTGIEAAPHLTGIDASPEQLKAIAKDYWDSGIRNIVALRGDEP
PGYDKKPFYAKDLVKLLKEVADFDISVAAYPEVHPEAKSAQADLIFLKQKVEAGASRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFVQLQKMAKVTNVKIPSWMFKLYDGL
EKDQTTRNLIGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGVRPSLAA
>A0A174CA94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalicatena contorta|TrEMBL
MKTTEIFKEHTVLSFEVFPPKRTGAVDTIYSTLEELQKLHPDFISVTYGAGGSENCKATL
EIASAVKNNYHIESVAHLPCIGLSKKDVLSQIRHFKEAGIENILALRGDIPKDGEMSGDF
RYAGELIAFIREHCSLNVIAACYPEGHTESENIAADIRNLKTKVDAGADQLITQLFFDND
YFYRFRERCFLAGIHVPIQAGIMPVVNKKQIERMVSLCGVHLPRKFAAMMERYEHNPEAM
RDAGIAYAADQIIDLTAQGVDGIHLYTMNNPYIAAKIYEAVHRVLAA
>A0A1H3K553|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas sp. Nm58|TrEMBL
MRSQKNFSPTFSFELFPPQTPEGVEKLRAARQQLAQFKPKFFSVTFGAGGSTRDRTFETV
LEILAEGHPVAPHLSCIGSTRENIYSILSKYQENGIRHIVALRGDLPSGMAQSGEFRYAN
ELITFIRKEFGNTFHMEVAAYPEYHPQARSAQEDFRNFKNKIEAGADSVITQFFYNADAY
FHFVDMCEAANLNVPIVPGIMPINKFSQLVRFADTCGAEIPRWIRKKLEGYGDDIASIHA
FGLDVVTDLCERLLKAGAPGLHFYTLNSAVLTTKIWQRLGL
>A0A3R6FKT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella stercorea|TrEMBL
MNISDILTSGGGEKHFSFEVLPPLKGTGTERLFSTIEKFRDFDPAYINITTHHSEFVYRE
LDNGQYERLRVRRRPGTVAIAAAIQNKFGVPVIPHIICSGATADAIEYELIDLQFLGIEN
VLLLRGDKARDDSQFVPTPGGHAHTTDLIEQVNRFNDGFFNDGTPIKNPGKKFHYGVACY
PEKHEEALNIDLDLKYLKMKQDMGADYAVTQLFYDNQKYFSFVEKARQMGITIPIVPGIK
PLAKLSQLTVVPRVFRCDFPQELAVEALKCKTDDDARQLGIEWSTEQCRQLYKAGVNNIH
FYTVSAVDSVREVARRLL
>A0A290S035|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas arctica A 37-1-2|TrEMBL
MDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVIIYDIQDESSRTNQDRP
FAFKQTVDPREYSHLLRNLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDLQNVVLVGSP
SSIGDIKLSLPDAYKAMAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQGCQFFISQA
VYDAQATIELITSYARTCKAQGITPQRIILTFTPCGGEKTLEFMQWLGISVPEATKWRML
DADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINLYRLLKAIME
LNLAEKLIA
>A0A2I1CMS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus novofumigatus (strain IBT 16806)|TrEMBL
MHVKDKLADNETAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVNVALSAAYKAGCTNILALRGDPPRDKEA
WEATEGGLRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
VITQMFYDTDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEAL
EPVKNDDAAVKEIGKRLIADMCRRLLAAGIKHLHFYTMNLAQATQAVLEELKLIPSEETP
LQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSIRDVTQIFVRYLEGKLDRLPWSDSPISGEANAIKDNLVQ
LNGRGLLTVNSQPAVNGVRSSHPVYGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNP
DLTYHAVAKNRELRTNTRDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQDIMDNWYLVNIVNNDFHNTYDLFDLFNGLEVKDLDVPVGPDTVETK
SQPNGAAPKNLP
>A0A139HD37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudocercospora eumusae|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTHQGFSNLNARLSRMAHSLRPLFVNVTWGAGGST
STKSLALAELTQRELGLTTCLHLTCTNMSRKLIDEALEQAKVLGIRNILALRGDPPRSEE
YRDDHDTDAAEDDSNKDFTWAVDLVRYIRKQYGDYFCVGVAGYPEGHSDQSHPEHQSVEH
DLPYLVEKTKAGADFIMTQLFYDVDAYEKYEKTLREHESGVFKTVPIIPGLMPVQSYQIL
RRTAKLSHAAIPSDVSKKFEEVKGDDEAVKKVGVDVISNIVEKMKGIDKIPRARGFHFYT
LNLEKVVAQILERCNLIPPSTPGVIANGPFGDDQTVAVEESDDFVLVENAKKKDQRRKSS
MANSQPRNRIIVSHTRASSTSSNRASSTSAFEARDDEAGVPKEKINSRANTLAISEGEGA
LGREATWDDFPNGRWGDARSPAYGQIDGYGVSLHVSAPDAKRLWGEPVKPEDISTSFRRH
LEGEIDSMPWSEESLQPETLTIKNELLQLINKGWWTVASQPAVNGVRSTDPVFGWGPKNG
FVFQKPFVEFFIPAAEWKKLQFKLEEHPQITFFAGNAQGDFVSSDEDSVNPVTWGTFTGK
EIITPTIIEAVSFKAWCEEAFGIWAEWQRIYKPGSESSKLLERIRKDYWLVSVIHHGFLE
KGALWNDLLEG
>A0A5I6R957|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Glostrup|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A854C8E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. W12|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTGVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGA
>A0A6P0TQV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO3C4|TrEMBL
MNRFRNAVKSGEFLVTAEVAPPKGGDPTHMIEMLEGLKGRVHAVNVTDGSRAVLRMSSLA
ASIILKNNGIEPICQVACRDRNRIGLQADLMGASALGLHNILALTGDPVKAGDHKDARSV
FDMESVRLLQMIAKLNQGIDWNEKALPDGATDLFAGAAVDPQSPSWSGLKKRFERKLLAG
CQFFQSQLISDFDKLEKFMNQIAVESNKPILAGIFLLKSAKNAAFINKYVPGVDIPEHII
NRLAKAEKPLEEGMKIAAEQVQIASKICHGVHLMAIKREDLIPRILDMAEISPIGE
>A0A8H6RLS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudocercospora fuligena|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFSNLNARLSRMAHSLRPLFVNVTWGAGGST
STKSLALAELTQRELGLTTCLHLTCTNMSRKLIDEALEQAKVLGIRNILALRGDPPRSEE
YRDDHDTDAAEDDSNKDFTWAVDLVRYIRKQYGDYFCVGVAGYPEGHSDQSHPEHQSVEH
DLPYLVEKTKAGADFIMTQLFYDVDAYEKYENTLREHESGIFKTIPIIPGLMPVQSYQIL
RRTAKLSHAAIPSDVSKRFEAVKGDDEAVKKVGVDVISEIVEKMKGIGKIPRARGFHFYT
LNLEKVVAQILERCNLIPPSTPGVIANGSSGDDQAVAVEESDDFVLVENAKKKDHRRKSS
MANSQPRNRIIVSHTRASSTSSNRASSTSAFEARDDEAGVPKEKINSRANTLAISEGEGA
LGREATWDDFPNGRWGDARSPAYGQIDGYGVSLHVSAPDAKRLWGEPVKPEDISTSFRRH
LEGEIDSMPWSEESLQPETLTIKNELLQLINKGWWTVASQPAVNGVRSTDPVFGWGPKNG
FVFQKPFVEFFIPAAEWKNLQFKLEEHPQITFFAGNAQGDFVSSDEDSVNPVTWGTFTGK
EIITPTIIEAVSFKAWCEEAFGIWGEWQRIYKPGSESSKLLERIRKDYWLVSVIHHGFLE
KGALWDDLLEE
>C9Y4P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter turicensis (strain DSM 18703 / CCUG 55852 / LMG 23827 / z3032)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVALLREVADFDISVAAYPEVHPEAKSAQADLLNLRRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGLELKT
A
>A0A176TB33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter atrinae|TrEMBL
MKVTDHIKKANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVD
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VVALRGDARKDESYFKATQGGNAFASDLVQQISDLNKGKYLHDDIIVEHNYDFCVGVAGY
PEKHMESPSLNTDLKRLKQKVDAGADYVVTQMFFDNNKYFEFVKKAREIGITVPIIPGIK
PLAVKRHLQVLPQVFKIDLPEDLIDAVEGCKDNKAVRQVGIEFAIQQSKELKEAGVPFLH
YYSMGKSDNIQAIASKLF
>A0A4R1RD50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariniflexile fucanivorans|TrEMBL
MKVTDHIKKANGKTLFSFEVVPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYIYVD
KGNGLFDKRITRLRPGTVGICASIMHKYNVDAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VVALRGDSRKDEPYFTPTEGGNAYASELVQQITNLNNGKYLHDDIEVEHNYDFCIGVAGY
PEKHMEAPSFNTDLKRLKAKVDAGADYVVTQMFFDNKKYFDFVEKARAIGITVPIIPGIK
PLAVKRHLQILPQVFKIDLPEELIEAVEACKDNKAIRQVGIEFAIQQSKELKAAGVPFLH
YYSMGKSDNIQAIAKELF
>A0A1D8KAT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidihalobacter aeolianus|TrEMBL
MTSLSREPQVFSCELFPPKTDEAAARLREERCKLAELGPRFLSVTYGAGGSTQTRTLDTV
LEIQRDSGIDAAPHLSCVGSTREHIREILDTYRSNGIRHIVALRGDLPSGMRDIGDFRYA
NELVAFIREETGDHFFIEVAAYPEIHPQARSAEDDLRRFKHKIEAGADSAITQYFYNPDA
YFRFVDECAHIGIDVPVVPGIMPITNYTQLARFSDASGAEIPRWVRKRLEGFGDDRASIR
AFGLDVVTGVCEALLAGGAPGLHFYTMNQSEATVALWERLGLPKAND
>A0A6M0HQM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. BTF04|TrEMBL
MPTASQHRASRDGYQPIRVSIEFFPPKSDEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMIKDTSLKPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPQDGVG
TAYRPHPGGYAQTADLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFENDVYLRYVDKVRAAGIDIPIIPGILPVQNFKQSANFARRTGASVPYWLAARF
EGLDDDVDTRRLIAAAVAAEQVLDLVDRGVSDFHFYSMNRSDLVYAICHLLGLRSQAPKA
AAKAA
>Q818J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7W2QB74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas juntendi|TrEMBL
MSLLKTALREHHFVCVMEFVPKASAERFAAMQAIMDRAQLCGWPMTVAIGDRVGSPLDMS
PLDALASFDRPVPALPHFSGKDRERHHLLAQLQRMEAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQAAPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMREMLEAEMAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGIHDLKQLLALEARLAYWQTHVHTLEQWAPA
WQASWQMPGLPAVTFHPPQANWRQGESRVDASFKEKARYHLMHGMHGLLFSRRNSLSKAF
GWAVRQPLWTTRLGAQVLHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVGQTAVLRERLIPCIEEQTRHRSSWPQWFAPPSP
RRVSPQPAPRTQPES
>A0A096CN04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor plautii 1_3_50AFAA|TrEMBL
MMDIRTYLSQGKPLLFDGAMGTYFAAHPGRAEERCERANLTRPEEILRIHRAYLQADCRA
IKTNTFAISGDLSDGNDETACDIVNAACHLARQAAQPYGAYVFADLGPAPRDHSRAPADL
YQTQAQWFLEQGVTHFLVETLSGDEGLPELAGWLKEKNPDAFLMVSFAVDHSGMTSAGRL
GSELYRFASELAGVDAVGFNCVSGPRHLLKYIQTLELSDKPLTVMPNAGYPTVLGRRTVF
GGQPDYFAGQIAQIVQAGASIVGGCCGTTPEHIAQTAQALKEPLPKCTVSAPKKLLKPAA
NASNSLWEKLEAGKRVIAVELDPPVDDDSAGFWEGVQALRGSGADAVTIADCPIGRPRAD
SSLLACKIKRDIGIEPLPHMTCRDRNLNATKALLLGLSMEGVHNVLVVTGDPIPTEDRNE
VKSVFNFNSRKLARFVHMLNENTLRTPFRIYGALNLNARNFDVELRRAQEKEACGVSGFL
TQPVLSAEALDNLKLAHKTLRGKILGGIFPVVSHRNACFLNNEISGMRVCDEIIHLYEGK
DRDAAEALAVTVSTAIAKEIFPYTDGYYLMTPFRRVALMEHIIQNIQQSCIS
>D5RIQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas cervicalis ATCC 49957|TrEMBL
MNHLADHAASTALASDRQGTLHRWLTGPRVAGLPVPSEQPAPALSFEFFPPRTEALEQQL
WSCIRRLEPLAPRFVSVTYGAGGTTQERTHATVARLVAETSLTPAAHLTCVGASRAEVDE
VARRYWEAGVRHIVALRGDAPAGEAGYVPHPEGYAYAADLVAGLKRIGDFEISVAAYPET
HPTAVSAEQDLDNLKRKIDAGATRAITQYFFDTELYLRFLDRCLAAGITVPIVPGILPVS
NFTQVKKFSAMCGASVPPWMGKLFEGLEEDADTRRMVAAALAAEQVRLLQANGVDEFHFY
TLNRADLSYAIAHILGARPKA
>A0A4Q2DSW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candolleomyces aberdarensis|TrEMBL
MRISQKIEQSTKDGKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGMETCMHLTCTNMPREKVDIALTDAKASGCRNILALRGDPPMGQDN
WEAVEGGFIHGIDLVRHIRKNYGDYFDIAVAGFPQHMLLPEAERDQEIQWLKEKVDAGVN
FIFTQMFYDVEMFLSWVRAIRAAGITIPVVPGINPIQTWNGFQKATRLSQTTIPRSYLDV
LEPIKNDDEKVRELGTKLVADMCRKILDSDLGIKGLHFYTMNLEKGTKMLLEELNLVPRI
ETIKPLPWRQCLTPTRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVSIKQTKESALQLWGHPTTISDISALFANFCAGNLAALPWSDSVPSNETGVIANQLA
RMNKLGFLTINSQPAVNGARSDDKVFGWGPANGYVYQKAYLEFFVSPEHLKLLLKHIERD
SNITYYVINKRGDLQTNTHSEGPNAVTWGVFPGKEIIQPTIVEALSFMAWKDEAYELGSQ
WARLYDHDSPSQKLIESVMDSYSLVNVVHNDFHNSDSIFEPFWKAGAEWEASQKGVNGNG
HALVNGHAAVNGA
>R7CCG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:62|TrEMBL
MIKDLFHTNRPTYSLEVFPPKKDADVSVIYDALDEFKTLHPSFISVTYGAGGNTAENTFA
IASYIQNQCGIEALTHLTCAAIPDRLFLKNFLTNLYRNGIHNLLALRGDKPQWMSDEQFD
ARFYDHASDLVTDVKEMFDFSVAGACYPEVHQEAASLSEDIANLKIKVDKGVDFLITQLF
YDNETFFRFLDEARNAGITVPILPGLMPITSAGQVKNIIGMSGTKIPKELADAIEKYKDN
PADLKKAGLDYSKRQMENLLAHGVDGIHLYSMNKVEIARAIYE
>A0A1G9PSD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kriegella aquimaris|TrEMBL
MKVTDHITKANGKTLFSFEIIPPVKGRNIQELYDNIDPLMEFNPPFIDVTTSREEYVYID
RDGLLDKKVTRMRPGTVGICASIKHKYDVDTVPHVLCGGFTREETEYLLVDCHYLGIENV
MALRGDAMKEEKYFQPTKGGHPYACDLVKQIEALNCGRYLHETVERDNCGDFCIGVAGYP
EKHLEAPSLQSDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVAAAKNMGIDVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVDSCATNRDVRQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIRAIAKELF
>A0A519QVN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp|TrEMBL
MSTLPAVENYRAHATPLFADVAGDIDVSFEFFPPKTEKMEETLWESIETLSPLNPRFVSV
TYGAGGSTRERTHNTVARIARETAIPAAAHLTCVAATKDEIDRIADDYWNAGVRHIVALR
GDPPTAGEKYATHPGGYENAADLVAGLTRLHPFEISVAAYPECHPDSPHAAADLDNLKRK
IDNGATRAITQFFFEPDTFFRFRDDAAKAGIEAEIVPGIMPVMNYASVVRMSGMCGTDVP
GWMERLFEGLDDRPAARQLVSATLAAELSRRLYAGGVRQFHFYTLNRAELAYAICHLLGV
RPQEKSA
>A0A4Y9J3B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Barnesiella sp. WM24|TrEMBL
MKVTDLIASNGKTGFSFEVLPPLKGRGISQLFRNIDVLKEFNPLYINITTHRSEMVYKNT
PDGLYQKVSERSRPGTVAVAAAIQQKYGIPAVPHIICSGFSRIETEYALIDLNFLGITNI
LLLRGDKAKHENRFIPNDNGYSHATELQIQVNEFNRGYFIDGTKMDIVTGEPFSYGVAGY
PEKHEEAPNIDIDIQYARQKIDNGAEYIVTQMFFDNQKYYDFVDRCRKAGINVPIIAGLK
PITTMNQLNLLPKVFHVDLPMELATELMKCKSDADAKQVGVEWCKMQAADLIAHNIPSIH
FYSLNATKSVEQVARAVY
>A0A5N7D3M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus pseudonomiae|TrEMBL
MHIKEKLGQNEAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREQEK
WEAAEGGLRYAKDLVRYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFIDWVKKCRAKGINVPIIPGIMPIQTYSAFIRRATWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIRDLSHLFVSYLEGKLGRLPWSDTPISSEAKTIKPNLIE
LNNRGILTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELITRIESNE
DLTYHAVSKNGELRTNTQDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDNWYLVNIVNNDFHNTYDLFELFKDLNVKDFDVEVTADNADSK
SQEAEATAN
>A0A7X4CG83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boseongicola sp. SB0676_bin_33|TrEMBL
MHLPGLSFEFFPPQGVQASFRLWEAVSELSPLGPEFVSVTFGAGGAQHDLTLETVKAIMI
RFDLNVAAHLTCSGATRETTLAVADSYSDAGVREIVALRGDPPSGADAFRPHHDGFEDSC
ELISALAHLNQFSIRASAYPDPHPESPAPGADVEWLKRKVDAGASSAITQFFFEAESYFR
FRDACDAARIDVPIIPGILPIEDWRRMKRFAKRCGAHVPAWLADAFEVALRDDRHDLLAI
SVCTELCSDLLDGGVEHLHFYTLNKPHLTREVVRALRAAPTADLRYVA
>A0A7L8CX53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. CW239|TrEMBL
MTPISFEFYPPKTDEQRVQLDRTAARLKAHDPDYVSVTFGAGGSTLSHTPEAIQRLRSEH
AYDAAPHITCMGGSRAEIRNLLKLYRAMGARRLVTLRGDVPSGMVSPGDLRYASELVEFI
RAETGDHFHIEVAAYPEVHPQARDAHTDLAHFLAKARAGADGAITQYFYNADAYFRFVDD
VRAAGIDIPIVPGIMPISNFSQIRRFSDMCGAEIPRWVSQRMLAYADDVDSVRAFGAEVV
AQLCQRLIAGGAPGLHFYTLNLARPTLGVLSQLA
>A0A437PBU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium oryzihabitans|TrEMBL
MVTTAFRRSRESRRPIRVSFEFFPPKSAEMEQTLWSSIERLAPLQPDFVSVTYGAGGTTR
ERTHNTVARMVRETNLNPAAHLTCVAATTDEVDDVVRAYWDAGVRHIVALRGDPAEGVGH
AYRPHPGGYARSCDLVAGIKRVGDFEVSVSAYPERHPEAPSLDVDIDALKAKIDAGATRA
ITQFFFDNDLYFRYLDRVQARGIDIPIIPGILPVQNFKQAANFAKRTGASVPDWLAARFE
GLEDDVGTRKLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRGTVAGEE
KAAA
>A0A8J3WKZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planobispora siamensis|TrEMBL
MRFDELVRSGGPVVTAEFPVVDTDMAALVRHADRLRGWADAVNVTDNTAAHAHASNVAVA
VALRGLGLEPIMQVACRDKNRLALQADIVGAALHGVRAVCCLTGDDVTAGDEPQARRVFD
LDGPQLIRVACALAEGRYLSGRAIDPAPELLVGAVENPGAPPYSHRVDRAAKKIRAGARF
LQLQICYHPDRLAAFMAGAARAGLTSRAAFLPTICLVKGAGGLRFMNEKVPGISVPAETI
DRVEKAADPSRAAYELALAQAGHALSLPGVRGLHLVDFRGGDAVPRLLSDLRISRRLTA
>A0A7W5EIX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter sp. Sphag1AF|TrEMBL
MAAISFEFFPPKTDEQKAQLDTTVKKLKPHSPDYVSVTFGAGGSTLSYTGETVTRLRKSH
GLSVAPHLSCMGGTRAEIADLLDTYKESGCRRIVALRGDLPSGMASPGDFRYAAELVRFI
REHSGDYFHVEVAAYPEIHPQAENALDDIRHFKSKVDAGANGAITQYFFNADAYFRFVDD
ATKLGVNIPIVPGIMPIANFSQLRRFSEACGAEIPRWIVKRMQAHGDDAKAVRELGADVV
AELCQRLLDGGAPGLHFYTINRARSTTAVLERLS
>K2MJP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor pacificus pht-3B|TrEMBL
MTTRPPQIDENPAGIELPLEPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANAQDVYER
AAIFDGWVDGINAVDASGANCHMSSLGICALLTRMGYATIMQIACRDRNRIAIQGDVLGA
AAMGVANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDEEKFLSGRALTTPPAV
FLGAAINPFAPPFDFRPLRLAKKIAAGAQFVQSQYCYDVPMLEEYMKRVRDLGLTEKCFV
LVGVGPLASARTARWIRSNVPGVHIPDAVVARLEGAGNQKQEGKRLCIDIINEVKEIDGI
SGIHVMAYRQEEYVAEIVHESGVLKGRKPWRREPRADDALVAERLDHILHDNASETPVDM
VKDVVSE
>A0A344L7J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis albispora|TrEMBL
MTSVVERLRGNETVFSVEFFPPRDDADEAVLWRSIRELEGFDPAYMSITYGAGGTSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNVLALRGDPPGDPYGEWI
AHPEGLNYAEELVALVRSLGDFCVGVSAFPYGHPRSADLETDTRHLVRKFKAGADFAIAQ
LFFEAEDFLRLRDRVAAAGSDALMIPGIMPLTTPRTLRKTIELSGATAPKSLLDRLTPLE
DDPAAFRAEGLDVVTEMCERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A1H6FKB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilum album|TrEMBL
MRIDQILRERRPVFSFEFFPPRTDEGQRQLEETIAVLRDDRPDFVSVTYGAGGSTRERTV
EVTKWMKQDLGIEAMAHLSCVGEPVSRLREILDELQAAGIENILALRGDPPRGESEWRPH
PQGLRYSVELIRLITSNYDFCVGAACFPEVHPEAESLEEDLRYARQKVEAGASFLITQLF
FDNALYFDFVDEARAHGIDVPIIPGIMPITNYKQIKTITGMCGASIPRSLERELRARADD
PDSVLELGVAYATLQCSDLLARGAPGIHFYTLNRSTATRAILAALRAAHPWTRAGSVV
>A0A1S9AXE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp. CRA2|TrEMBL
MKVTEHLARAAGKTLFSFEVLPPKKGENIQTLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFTKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFVPEPDGHAYACDLIGQVADLNKGAYLDEEQDDTWATNFCIGTAGY
PEKHFEAPSHAADLRYLKHKVDRGAEYIVTQMFFDNEQFFSFEKRCRAAGIHVPIIPGLK
PITTKAQLTALPRSFFLNLPDELVDAIHLAPDNAAAREIGIEWCINQSRELMAHGVPVLH
YYSMGKAESVRKVAAALF
>A0A2G1ZWH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaera sp|TrEMBL
MHMQDVFKRHRTTFSFEFFPPKSEKGSGTLFKTIADLERLDPAFVSVTYGAGGSTRDLTN
DLVVRINKETPLNAMPHLTCVCHSAEDIESLLVRYAEQGISNILALRGDAPANACGHNHK
DDAYQYAAQLVAAIKRFNDKGTHPSGKGFGIGVAGFPAGHPSTPNRLQEMDHLRAKVDAG
ADFIITQLFFDNAMFLDFRDRCRLAGITVPILAGIMPVTTLSGMKRMADLALGTHFPAKL
MRALDRTNGHDESVRRVGVHWATQQCADLLDAGVDGIHLYTLNKSTATRDIYASLGVMSS
SQLSSD
>A0A5D0WLB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. BW1|TrEMBL
MSTPIIHPNWARPAINMVEGYSLEMTAKDIASLREAAPGIAPETPIAVTFLPGEAFEARI
AAARLVRELGFEPMPHFSARRIVSEDEFREYLKAVTKEAGVKRCFVIAGDPSEPEGPFAD
SSTLIATGAFEDAGITAIGIGGHPEGHPNMSDEECWSVLQTKCEEIEKRGMAPLIVTQFA
FDAGAVLSWLAELRKRGLAAPVRLGIPGPAGIKTLMRFAARCGVGASASVLTKYGISITK
LIGTAGPDKLVDQIEKGLTEEHGAVRLHFYPFGGLTKTVGWINDYAKSH
>A0A0J7JHS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Burkholderia pumila|TrEMBL
MKPIEFSFEFFPPKTEEGVQKLRASRAELRKLSPKFVSVTFGAGGSTQQGTLDTVLEMAS
EGFEAAPHLSCIGSSKQALRLILAQYRDHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQEHGDWFNIEVAAYPEFHPQSKSPLADLENFARKVKAGANSAITQYFYNADAYFEFVD
EARKLGVDVPIVPGVMPITNFSQLMRFSDMCGAEVPKWVAYRLERFGDDRESIREFGLDV
VTGLCRRLVDGGAPGLHFYTLNGAQASKSICERLGLKRAPEN
>A0A0W8C5I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora nicotianae|TrEMBL
MKVIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEILMHMTCTNMAEADIKKALDEAKDAGIQNILALRGDPVRGASS
FDECDRGFSHAVDLVRYIREKYGNHFCIGVAGYPEGHVEIKDKKADIQYLKEKVDAGADF
VITQLFYDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTSFCNTFVPDEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRASESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSNTSTPRERRAMWGEAPAAKEDVRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGALSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
PSIQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEPGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSPATSP
>A0A6A5B7E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea dispersa 625|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEATLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRAIARDYWNNGIRHIVALRGD
LPPGGGKPDMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNAMFD
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPTLAA
>A0A3G9J4G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides baekrokdamisoli|TrEMBL
MTGLPELLRSGRRSFSFEFFPPKDADGEAKLWEAIEALEPYQPTFVSVTYGAGGSTRDTT
VRITERIARETSLTPVAHFTLVGHTVEEIDRVLDAYSAAGVENVMVLRGDPSEGPRAEWT
PTKGGLTYAADLVERIDGRGGFGIGVAAFPEGHPSAESLDVDADVLVAKAKAGAGFAITQ
MFFRASDYFDLVERVRARGADIPIVPGIMPILNLAAIRRQGELIGTSVPDEIVDRISAHG
DDAAAIRAEGIAIAAELCEELLAGGAPGLHFYTLNRSTATLEIFEKLQITAS
>B7LUQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8J5E1L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradysia odoriphaga|TrEMBL
MHAINGESKPNKPSLIVINTQQDKSAQSIKVVDLIRTRTRTKERFYSIEVSHSSSLLLNF
NDFLVQPLFTSVTWFSDNVEVENYSVEPSVRLINAITSTPTLLHLTCYKLTEDKLAKILT
KKLTNVLALRGDAVTPNQIFRHAIDLVRRIKHSSSNTSLAVAGYPEQHPESISLDMDMKY
LREKVEAGADFIITQTCFSSAKMKEFIRNCRDVGIRVSILPGIFVPSTFSSLLAMCRICK
IRVPTEEFRMYKMLKDDPKAFQDYAVQRTVLLLNDLFYNNDDDAAVGVHFFTLNNFDMIH
RVIANFDFK
>A0A2X1C6Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella melitensis|TrEMBL
MGFYGLSCRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A2X0M9G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbotryum saponariae|TrEMBL
MPIASGGMTPLSCQTALGGFATRASDGFVIVVVAKLWIAGVILAERDGRPWWSFEFFPPR
TPDGWVNLYDRIERMKQLGPIFVDITWGAGGATSEATTTFVKHAHSELGLETCMHLTCTN
MPVSMVDAALKDAYDSGCRNILALRGDPPRGSEEWVQTEGGFNHAIDLIRHIRKHYGDYF
DIGVAGFPEGHPQAESAELEMKHFKAKIDAGANVIFTQMFYDANVFINWGRRVREAGITV
PIVPGIMPIQTFASFKRRTDFAKTIVPQELWDLLEPIKDDDLKVREVGTKFVADMCRKVL
TAGIGINGIHCYTMNLSRGTEMLLEEMNFVAQADIVKPLPWRVSLTQKRRTETTRPIFWS
NRTRSYLSRTADWDEFPNGRWGNQASPAFGDLDSLALSLPHKAQDATTLWGEPTSFEDVA
QLFARFCTGDLKALPWSDQPVARETTVISDPLKKINSAGFLTINSQPRVDGAGSSDPVHG
WGPRGGYVYQKVSCRCPAQLNIYLFETDMTRSVFVQAYLEFFASSAHLDDLLKVLQRYPS
MTYHAVNKAGDLQTNAAPGPNAVTWGVFPSAEVIQPTVVDGLAFLAWKDEAFELGTLWAE
LYSKTRQESAKVISEIFDTFYLVNLVQNDYRDEDELAIFKPFFEVIDGTKTATANGVNGS
H
>A0A351Q7U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MTISKILEQKKTLLSFEVFPPKQQANFENTVNAAKELCNLNPDFISVTYGAGGTTRENTV
EIASKILSFGTPALAHLTCVGNTIDEAKNIISQMKKNKIENVLALRGDIPQGISNPLSKE
LEHANVLAKILKDEGFCVGGACYPEGHPESHNRQEDIDNLKYKIDAGVDFLTTQMFFDNN
MLYSYLYQIQSKGIHVPVFAGIMPITNSNQVSKMVKLSSAYIPAKLLSICDRFSENPEAM
RQAGIAYATDQIIDLISNGVRGIHIYTMNKPSVAQEIYKNVDKIISATNS
>A0A1C9W4J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbulbifer aggregans|TrEMBL
MTNNTRISFEFFPPKTPEGREKLYKTRETLQEFQPAFFSVTYGAGGTTRETTADIVTNLR
RDGISIAPHLSFGGDDEETVLALLDRYQEAGVDRIVALRGDMPSGMGAVAQLVYANELVA
FIRRHTGDQFHLEVAAYPEIHPEAEHYDADIGYLKGKFDAGANSALTQYFYNPDAYFYFL
DQCEKAGIDAPIYPGIMPITNFTNLARFSKNCGAEIPRWLRRRMESFSNPEDTRKLGLEV
VTDLCETLLEGGAPGLHFYTMNQVDPTAEILRSLSLD
>A0A1B1FYP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flammeovirga sp. MY04|TrEMBL
MKVIDRLIQAEREKKTLFSFELLPPVRGKSIQSLFDAIDPLMEFNPAFVDVTYHREEYVY
KELPNGLFEKSVQRHRPGTVAVCAAIMHKYNVDTVPHIICGGFSKEETENILIELNFLGI
ENILALRGDAAKGEAAFTPHPKGYKYASELVEHVDQLNKGEFMYAESGFKGGFCMGVAGY
PEKHMDASNLDTDIKYLKQKVDLGAEYIVTQMFFDNQKYFDFVKRCREAGITVPIIPGLK
PLTTKRQLTLLPNIFKLDFPQELIKEAEKCKDNKAIKQLGIEFGIQQAKELMEFGVPSMH
YYSMGRSTSVKDIAEAIF
>A0A520HY70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
MTISVDQLAEARCALETPLYADVGGDLGVSFEFFPPKNEAMETQLWDAVRTLEPLGPRFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATKAEIDQIAEEYWAAGVRHIVA
LRGDPPTAGATYAQHPGGYENAADLVAGLKRLHPFEVSVSAYPECHPDSGDAAADLDNLK
RKLDAGANRAITQFFFEPETFFRYRDQLAAAGVDAEIVPGIMPVMNFASVKRMSAMCGTD
VPAWMARLFEGLDDHPAARQLVAATVAAELSRRLYAGGVRQLHFYTLNRAELAFAICHLL
GVRAKPAQAAASRAPPAGGR
>A0A2M9E0D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium NML91-0213|TrEMBL
MIPLSFEFYPPKTDDQREQLDRTARRLKTHAPEYVSCTFGAGGSTLSYTPETVRRLRQEH
GLEAAPHLSCVGGTRDEIRELLKLYRAIGCRRLVALRGDMPSGMGHAGELRYAADLVAFI
RDETGDHFHIEVACYPETHPQAEDAHLDLRNFKAKVDAGANGAITQYFYNADAYFQFVDD
ARRLGVDVPIVPGVMPIANFSQLRRFSESCGAEIPRWIARRMQGYGDDVDAIREFGADLV
ARLCQRLIDGGAPGLHFYALNLARPTQAVLARLG
>A0A1L3GL10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophotalea acetylenica|TrEMBL
MHIQDIFSHHATTFSFEFFPPKTDKAAQRLYETIRQLETLKPHFTSVTYGAGGSTRERTH
DLVMRIREDSSLDPIPHLTCVCSPEQEIRRILERYAAAGISNILALAGDPPPDMPGYDRS
QDAFPHAADLVRFIRRFNDEGLHPDRRGFGIGVAGFPEGHPATPNRLLEMDHLKAKIDEG
ADYICTQLFFDNRDFYDFRERCELGGIKVPIIAGIMPIASVEGMKRMAELAAGARFPAPL
LRAVERCQNDPEAVRRIGIHWATEQCRDLLDNAVRGIHFYTLNNSDATRQIFQCLGLNAN
TQ
>A0A6X8EN07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enteritidis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSACIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1G0LXS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium GWC2_55_20|TrEMBL
MNEKPYTIIDRLRREVLTGDGAIGTMLYAKGVGLDSNFEHLNLVRPALVRELAGEYAAAG
AQVIETNTFGANYTKLSAIGLGHKVVEINLAGAAIARQAAAGRDILVAGSVGPLVQIKGD
DRELSRDEMEAVFRVQCNALAEGGVDLLLLETFSSLEQLQAALRAARGCGLPVSASMAFM
EGGRSADGTSVERFCGAMEAAGADIIGANCGAGPLELLKVIKRLAMLTDKPISAYANSGF
PEYRDGRYIYRATPEYFAGMAAEMAAAGANLLGGCCGTTPEHIAAIAQRIGGATPATRSR
IPHITVSEPVEETRQAASFLDHWGARKVITVELDPPKGTDCSRIIAGSRRLKQAGAGAIN
LAENPLARPRMGNIALGSVIQREVGIEVIVHVTGRDRNLIGMQSDLMGANLLGIRSILAV
TGDPATMGDHAGAKSVFDLHSFTLIKLLSDMNRGVNAIGNPIGEGTGFTIGAAFNPNTRN
MAVQAERLRRKVANGARFTQTQPIYDPAILFEALEATRDCGIPFLPGIMPLVSERNAEYL
NNEVPGITVPDAVRARMKGLEKEAGAREGLAIAKEFIDATIGAVGGYYLIPPFGKHELAE
ELIRHIKQREREQQ
>A0A7G9S983|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas rhizophila|TrEMBL
MNRLSQDALGNHAPLFAKTRGDVAVSFEFFPPKTDAMAETLWRSIETLAPLKPRFVSVTY
GAGGSTRERTHATVSRIVRETELTPAAHLTCVGASRDEIDEVARSYWQAGVRHIVALRGD
PPEPGTPYAPHPDGYATAADLVAGLKKVADFDISVAAYPETHPEADCPDSDLENLIRKID
AGADRAITQFFFSADNFFRFRDKLAARRPDVELVPGILPVTNVATARRFAGQCGAAIPDW
MDGVFEGLDELPAARQLVAATIAGELCGQLYAGGVRHFHFYTLNRAELAFAICHLLGVRG
>A0A6P2V1W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MSDQLQLQGDFAPSKRGAALHPANPVLSLLDDFSLEMSGKDQPALQEARDVIPKGTLVNV
TFLGNENLDLRVSTAQSVRESGFLPVPHIAARRLQSEAQLREFLDRLREVGANERVFAVG
GDPRSPEGPYQDSLALIRSNLLPEYGVTHVSIAGYPDGHPDIEEDRLWAALAAKYVTLAE
QGIDVTILTQFGFDVEPVLRWIYKVRERGIEARIRIGVPGPAGVKRLLAFAARFGVSSSA
SVVKKYGLSLTNLFGTAGPDRFINSLAEQLDGKGLGQVSLHFYAFGGLQPTGAWIRDFRK
GA
>A0A011NDE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mannheimia granulomatis|TrEMBL
MNYATQIDALNQHIADINHKINVSFEFFPPKNEKMETMLWESIDRLSRLNPKFVSVTYGA
NSGERDRTHSIVKSIQDKTGIISAPHLTGIDASPEELKVIAKDYWASGIRRIVALRGDVP
QGYNKELFYASDLVALLKSVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVSIGIDCEIVPGILPVTNFKQLQKMAKVTNVKIPSWMGKMYEGL
DDDQTTRNLVAASIAMDMVKVLSREGVDDFHFYTLNRSELTYAICHTLGVRP
>A0A081B5Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. MR-S7|TrEMBL
MSLPVSFEFFPPKTPEGAAKLRTVRQQLYARAPQFCSVTYGAGGSTHEGTFSTVREILAE
GVDAASHFSCIGATRDSVRAQLAELQGMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
RAETGSAFHIEVAAYPEVHPQARSADADLQAFAAKVRAGADSAITQYFFNADAYLRFVDD
ARRLGLDVPVVPGIMPIMGATQLMRFSDACGAEIPRWIRLRLQGFCDDAASIRAFGLDVV
AQLCEQLRRAGAPGLHFYTMNQSAATLEICQRLGL
>C4LI37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium kroppenstedtii (strain DSM 44385 / JCM 11950 / CIP 105744 / CCUG 35717)|TrEMBL
MSSPNSAHTPTNRPPRPIYQQVPVSQAISLPTPGPVPFSVEFMPPRDDAAERRLNDAAAT
FHDLGASFVSVTYGAGGSSRSRTIRIGQELAHTPLTTLVHLTLVQHTVDELKEIIASYQE
CGLTNILALRGDPPGDPTGEWVSTPGGLEHAIDLIKLIQECDTQRQFEIGIASFPDKHYR
ATDLDSDTAYTIAKLRAGASYSITQMFFDVEYYLRLRDRLAAADPVHGAKPVIPGLMPIT
SLKSLRRQRELAGCRVPADLEERLEKATVTGDPSDPRVRQEIRKIGIAHTTAMAERLISE
GAPDLHFMTLNFARATQEVLHNLGMAPAWGTDHGHDAVR
>A0A0E0Y986|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O104:H4 (strain 2011C-3493)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEIYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>U5VTP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes friuliensis DSM 7358|TrEMBL
MSLGLPSRLPTSPAIGELIRRPDPTFSFEFMPPKSREGEQLLWQTIRELETLRPDFVSIT
YGAGGSTRDTTVAVTERVATETTLLPMAHLTAVGHSVAELRNVIGRLAGAGIRNVLAVRG
DPPGDPNAEWVRHPEGVLYAEDLVRLLRESGDFSVGVAAFPYKHPRSADIESDTLNFIRK
CRAGADFAITQMFFEADEYLRLRDRVAAAGCDTPIVPGVMPVLRMATIARAAQLSGAPFP
PGLLSRFERIADDADGVRRLGIDLCSEMCQRLIDEGVPGIHFITMNRSTATREVWQHLAA
NVAA
>A0A2E5H9B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVVDYIKNSNKTIFSFEIIPPLKGKGIEDICEGIDPLMEFNPPFINVTYHREEYDYKKM
GNGLLKKVSVRKRPGTVGICAALMNRYKVDAIPHIICGGFTKEDTESALIDLKFLGVDNI
LALRGDPMKNESAFVPTDGGNKFAIDLIKQINDMNNGQYLYEETKNSPSNFCIGGAGYPE
KHFEAMNLKSDLKHLKEKVDAGMEFIVTQLFYDNKKFLEFEKKCREIGITVPIIPGLKPI
TNLRHLTFIPKFFNTNFPEEFSNELEKCKTNDEVKKVGIEWSTIQSKELVKAGVPVLHFY
TMGKGESVKNIASKIF
>A0A2N0M0N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium MP-SAtl-SRR3965592-G1|TrEMBL
MKITEGSFEATGHTSVICDFSPPRSGDAAVVGQAQIDADFISVAYNPGRAVRTNSAMLAA
AIQNSGKDAVFTLATRDMNKLALQTQLLGAQLLGVQNVVVVQGDPFGERDQTRVASVNDY
TPTGLIAAIAQMNQGQDFKESKLGQPTDFCIGATMDLGRGIEEEAQLAVRKVEAGAEFLI
TQPIFNVDHVARYRESFGYHAGKAGTVPIYFGLQILEKNGVLFSSVPESVRSELEGGRTG
VDIALELYRKFQKARLNNIYLMPPIKRGGARNYEAAKEFLGKIKKA
>A0A291AAR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas frederiksbergensis|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKNDLRGLLTQYKAAGIQRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEIAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQSFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1F8MLL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_51_52|TrEMBL
MKAGTNLEKILESGRFAVTAEAGPPKGTSAAVIQRKAELLRHCCDAVNITDNQTAIVRMS
SLAGCVITKQAGVEPVMQMVVRDRNRLALQADILGAIALGIGNILCLSGDHQKFGNHPQA
KGVFDIDSIQLIQMMKKMRDEKKFLNGEEISGDVPIYIGAAANPFADPFEYRVKRLAKKV
KAGVDFIQTQAVYDVPRFAKYMKMACDMGLDKKVHILAGVIPIKSLGMARYMRDYVSGVT
VPDEIIDRLKGAEKAKEEGVNIILEIIEQIKEIPGIHGIHIMAVGWEDIVSEMVERAGLM
PRPVL
>A0A2H0Y6W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG08_land_8_20_14_0_20_41_16|TrEMBL
MTFKEKLQAGKFLVTSEIGPPKGIETKQLLEDAELIRTRVDAINVTDLQSSVMRLGSLAV
CSILKQHGFEPIFQMACRDRNRLALQSDLLSAAALGIENVLILTGDHTTLGDHPNAKPVF
DLDSVQLLQAARRLQEGSDMNENKLLGASPKFCLGAVVNPGADPLEPQIMKMEKKIAAGA
EFFQTQAVYDLKVFENFLNKTKHLKTKIMAGIVLLKSAGMAKYMNKNVAGVFVPDNLIKE
IEGAQDKVARSVEIASRLIKELKPICDGIHIMSIGWGKVVPRVLDASAL
>U1R5K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aggregatibacter sp. oral taxon 458 str. W10330|TrEMBL
MSYAKEIDNLNQHLASLDGKINVSFEFFPPKNEKMENLLWESIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLEAAPHLTGIDATPDELRAIAKDYWDNGIRRIVALRGDIP
PGYNKPPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMTSVTNVKIPAWMAKMYDGL
DDDQTTRNLVAASIAIDMVRVLSREGVNDFHFYTLNRSELTYAICHLLGVRASL
>A0A7X5I4U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKIKDIICAKRPTLSFEIFPPKPGADFEPVKKAAEEIAKLKPDFISVTYGAGGGTSSNTI
KIASYIQQLGVTALAHLTCASSTKYEVETVLQEIKQNNIENVLALRGDIPEGSDFPQPNQ
YRYASELVEHIKKSSDICVGGACYPEGHTESPTRAEDITHMKIKADMGCDFLTTQMFFDN
NILYNYLYHIREAGITTPVLAGIMPVTNGKQIARICQLSGTILPQRFRAIVDKFGDKPES
MKQAGIAYATDQIIDLIANGVKGIHVYSMNKPDVAAKIVENLSEIIR
>A0A836DB18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salix suchowensis|TrEMBL
MASLKRLFCRKAIFCVKKHASRAREDGVMEREISQKIQQSTKEGKVWCPLSIFHQERPRL
YQGLQNLLDRIERMRALGPEFIDITWFGLFTLFCKYVAESRARNAGGRTSDLTSEMVKTC
QSMIGVETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPQGKDEWEAIEDGFVH
GIDLVKHIRRIYGDYFDIAVAGFPQHMLLPPDELAFEMKCLKEKIEAGVNFIFTQMFYDV
EIFIDWVKAVRAAGITIPIVPGIAPIQTWNGFVRATSLAKTIIPQSFTEALEPYKNDDEK
VRAIGTRLVADMCRRILDEDLGIRGLHFYTMNLEKATKMLLEELNLVPRIETIKPLPWRQ
VRTRLLVRVIERQETIRPIFWANRAKSYISRTENWDEYPNGRFGDARSPAYGELDGYEDA
LKLWGQPETVADVSSFALPWSDQPVAGETTAIAQHLAKVNELGFLTINSQPAVNGARSDD
KLFGWGPSNGYAYLEFFVNPTLLNILLSHIERDSNITYHVINKRGDLRTNTQSEGPNAVT
WGVFPGKEIVQPTIVEAVSFMAWKVRSSRIIISTTYLLAPQDEAYELGQQWVVSDIMNTY
LLVNVVHNDFQDPEAIFRPFYQAGAEYITKIQSQARVATDH
>A0A7X5IPM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MMDIRDELNRGVLLFDGSMGTYYASLYPDGERVESANRQHPGRVRAIHTAYLEAGARALK
TNTFSPFDVEGETLAQTLEAGYTLACEAAKPYGAAVFADLGPSAQSIEDCLRAADCFLSL
GAENFLFETFSDFAALDRVASYIKSKRPSAFVLTSFASNPDGVTRHGLSAAALLRQADAC
AEIDAAGFNCMSGPSHLLRLTESLQTLPRLLSVMPNAGYPAIVRGRTVYEGTPGYFAERM
AALTAAGAKILGGCCGTTPEFIRETRKALDTQRPAPKSVIASVQSRITLTARKEGRNRLA
EKLDAGQRIAAVELDPPVDADVSGFLTGARRLVEAGADTITIADCPIARPRVDSCMLAAK
LRRELGIDPIPHMTCRDRNVNATRALLLGLSIEEVHNVLVVTGDPVPSAERDEVKSVFSF
HSAILADYIRKLGSENAVVPFRVFGALNVNAANFDAELKKALRKRDAGVCGFLTQPVMSG
QAFENLQRAHEEMPEMKLLGGVIPVVSERNALFMNNEVSGIEVPEDIVRRYHGLGREAAE
ALAVELSVGFARRMEPFTAGWYFMTPFQRVGLIERILHALRS
>A0A6J0P546|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raphanus sativus|TrEMBL
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSHGPSFCDITWGAGGSTA
DLTLEIASRMQNAICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEADGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAFGIHFATEMCKKILAHGITTLHLYTLNMDKSAIGILMNL
GLIDESKVTRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYGTLSDYQFMRPRARDKKLQQEWVVPLKGIEDVQEKFKELCLGSLKSSPWSELDGLQPE
TKIINEKLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSEDKLD
TLVEKSKAFPSITYMAVNKAGNWVSNVGEADVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKKSYFLVSLVDNDYINGDIFSVFA
>A0A7X7KU60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MILYDGAMGTYYRMLFPGDPLRLEEINLQYPERILAIHRAYLAAGATKIKSNTFALLPFV
MGLEISECQAMLRAAWKLATEAVRSSAVCEAAVVADIGPHPLGATADESGIVAADYHWIV
AELLQLGAREFLFETQDSLALILPACRLIQERLPEATVTVSFSANQAGFTKSGSKLANLL
QEAELETSITYTGLNCDLGPTLLSKLYLEHAHFEKLQYLSPNSGLPEREIGRGRTAKDAE
YFAQAFLPAWEKGATQLSGCCGTNPSDIEALAALFGGRETGRKPSAPAIETTVAPSEPVT
REISSWYSRLMAGEKIIAVEYDSPANEKVKKYLEGVQELARAGADLLTIADCPIGRARMD
SSLTASRIHTEYSLATLPHLTCRDRNLNATHALLLGLAAAGIHQVLIVTGDPVPLEDRAQ
IKGVFNTDSVHLIRYIHELNQELETPFILCAALNINARNFSVELARAAKKAEAGAAVFLT
QPIFTERAIENVCRARAELPPTVKILAGIMPLVSYKNASYMQHEMSGMDVPEEVVKRYEG
LDRTQGEELAVELSLELMAKLHACADGFYLMTPFQRSKLTARICQLWKNQHYK
>A0A1F0BXZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC070B10|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>H5SZC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis IO-1|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKHIKKILALRGDISDEPMKDDFRFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPEKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>A0A348WG84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius nubinhibens|TrEMBL
MTTPAISFEFFPPKTLEASFRLWDTVQTLAPLEPRFVSVTYGAGGTTRQLTREAVETLHK
SAGLKVAAHLTCVDASRSETLAIADDFARAGVTDIVALRGDPPKGSGGFRPHPDGFEDSC
ALISALADTGRFNIRVGAYPERHPEAADDAADVDWLKRKIDAGASEAITQFFFEAETFLR
FRDRCAKAGIDAPIVPGILPIENWSNTRRFATACGTGVPQWLDDAFDKATRDGREDLLAT
ALATELCSDLLEEGVETLHFYTLNRPELTRDICHALGVTPKVKLRDVA
>A0A0K8N264|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter frateurii NBRC 101659|TrEMBL
MIRSLDQVRADLMRESSIELLPSRILELSGVLPDLNRGSRVFVTWLPGIPFAEVLAACDL
LKLCGYLPVPHVAARSIKDAEHLRNICAALIERDIPRMLLIAGGADKPAGIFTDTVQVLE
TEIPAQAGIRTVYVAGHPEGHPQASKKQLEQYLLRKQELARTQGLNMQIVTQFCFDAAPV
LDWEKRLRAAGIRLPINLGVYGLTTPKTLVRYGLACGVGQSLRFMQKQRWKLHRWFTPCN
PRDLVDAIAGSIAETPDTLFHGLHFYPFGAIARTLEWRRNLSCSSTGEPS
>A0A136M7K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Brocadia sinica|TrEMBL
MSSIAAGRIVLDAGLEPIIQMTCRDRNRIAIQSDLLGAAALGAKNLLCLTGDHQKFGDHP
MAKGVFDMDSIQLIQMVKALRDEKKFQGGQELKASEPRFFIGAAENPFADPFKFRAIRLA
KKIAAGADFIQTQIIYNINKFKDWMKMVTDMGLHEKAFILAGVAPLKSAGMARHMKHNVP
GMDVPDEVINRMTAASAAKKGKEEGIKICLEVIEQVKEIKGIAGIHIMAVEWEEAVPEIV
KETRLYPRPLL
>A0A1Q7CPR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_2_20CM_2_66_6|TrEMBL
MRTPRYEVLPTDNAADLVAAYVPRDITLTVTASPRRGMPRTIHLAVALAKLGYHAVPHLS
ARLIRDKVELGQILDALKAAGITEVFVVAGDAREPAGPFPDALSLLAALPPDHNLTEIGV
TGYPESHPFIHDDMTIQAMWDKRRLATYIVSNMSFDPEGVKRWVERVRNRGVELPIYIGM
AGVADPARLLRLSTKIGVADSARFLRGHPSWVARMFRPGGYEPARFAGALLPDIALPERR
IAGLHIYTFNEIEPTERWRREMLAQIR
>A0A558DBG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azoarcus sp. PHD|TrEMBL
MNDTELSIEFFPPQTEEGAEKLRAVRARLAELRPSFFSVTYGAGGSTRERTFATVKEIAA
SGSEAAPHLSCIGSTRDSIRAILAEYAEAGIKRIVALRGDLPSGVGDAGEFRYANELVAF
IRAETGQRFRIEIAAYPEWHPQARSPKDDLLAFKRKAEAGADSAITQYFYNIDAYLHFVD
AVRGMGVDIPIIPGIMPIASFSKLARFSDACGTEIPRWMRKKFEAFGDDSESIRAFGLDV
VTAMCEKLIASGAPGLHFYSMNQSALTTEICQRLKLA
>A0A0Q4LYP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf42|TrEMBL
MTPTISDMEEARRALDAPLFADLAGDCSVSFEFFPPKNEKMEAALWETVRALEPLAPKFV
SVTYGAGGSTRERTHATVERIARETSMPAAAHLTCVEASRAEIDEVAQAYWAAGVRHIVA
LRGDPPTMGQKFTAHPDGYENAAALVTGLQKLHPFEISVAAYPECHPDSEHQAADLDNLK
RKIDAGATRAITQFFFTPEAFFRFRDAAAAAGINADLVPGILPVSNVGQVRKFAGMCGAA
IPPWMDRLFEGLDDHPGARALVAATVAAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLM
GLRPKAMAIAAAA
>A0A1I3ZS48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. KH9|TrEMBL
MSVVAEIPTTAVPTSAPPPSAAPAPTVPEHSRVARRRSEQAGALDRPTVSFELFPPRNPD
AAPRLWATVRELETVEPDFVSVTYGASGHTRQTTRALVRRLLRETSLNPIAHLTCVGTSR
EEVTTIVEEFLDEGVRAFLALRGDPPAGEPDWRPHPQGVHTAAELVELLRDIERRRCGRS
AAQAVRARVRPLSVAVAAFPRGNHATGGTRAQDVQALLAKQEAGADFAISQVFFDAEAYL
GLVAEARTAGVTIPIVPGIIPTTDPERLLRVQELTGVPVPGRLLDVLGSTDDPVERHRRG
TQAGVDLVNRVLDGGAPGVHVYTFNKHEAALDLLDGADLVGGRRSAVAPHDLTVPGGTPA
GTTTTTPRGTLS
>A0A846ZPE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleiagrimonas citrea|TrEMBL
MTAISLEFFPPKTDKQRAQFESALPQLRKLDPDYASVTFGAGGSTLSYTPQTVKALMNAG
LDGAPHLSCMGGTRAEIAALLDDYKAMGCRRLVALRGDTPSGMAGPGDFTYASELVAFIR
EYAGDHFHIEVACYPETHPQADDALADLRHFKHKVECGANGAITQYFFNPDAYFRFVDDA
RKAGIEVPIVPGIMPISNFTQLKRFSDTCGAEIPRWIVKRMQAYYDDVESVRALGADIVA
EMCRRLLDGGAPGLHMYTLNRAVATMAVVERLN
>A0A8C2RSE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capra hircus|TrEMBL
MFPGPNCSSRRVLQLPRTSVDLISTQTLRSAAPRPPPPIRLQGLVPQPSLSPGILCPPPR
AGPSHSFKLFLCHGSAQSGTPAGEVSSFLRNSEVRGLSLPPAEMDRPKPKVFPVGHCCPS
LGMRALEAGSGRLSVPPSISRISAMVNEPRGNGGPGPRWEGSSSGSESSKDSSRCSTPGL
DPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHP
AGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITGHLHKAKQLGLKNILALR
GDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEK
VAAGADFIITQLFFEADTFFRFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVP
QQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLG
LWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAF
GELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWND
EPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFT
SRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDP
VSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVE
DTFELLSRPPQDERETEAL
>A0A853CID5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus daqingensis|TrEMBL
MTRTVKDRATAARETMQRIRTNPALVERTTAARDAVQKAVHTAVQKVVTDRALVVRDPAT
RRTLQRVFGDLGYEVIPFKKTEQAVLDTVPTDVRLTVTASPAKGQDATVDLAVSLAAAGY
TVAPHLSAQQVRDRAHLAEIVARCREAGLTDVFVVGGDPTDTPTEFPDALALLTALHELD
HGFTDIGIGGHPEGHPAVSDDVLFQALKDKAALATHIKTQIVFDPKVILDWARELKNRGI
DLPVHIGVPGAVHRQKLLRVSGGLGIGESAKFLKKQQTMFWRFFIPGGYSPDKIIKGLAP
HIGKPDNHIEGFHVFTFNDLGPTEAWRRRTLENLA
>A0A7U9GW49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae subsp. pneumoniae KpQ3|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A853CME1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus daqingensis|TrEMBL
MTPTVRELLQEGRPTWSFEFFPPKSDDAERQLWTALRELERLQPSFVSVTYGAGGTTREG
TVHVTERIAHETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNIMALRGDPPGSDPQAD
WIPHPEGFSYAAELVELIRSMGDFSVGVAAFPERHPRSTDWATDVDMFVAKCRAGADFAI
TQMFFRPEDYLRLRDRVSARGCDVPIIAGVMPVTNVKMINRIVQLSGQAFPTDLAARFAA
VDGETPEARAAVRALGVEVATELCARLLAEGVPGIHFITMNRSTATREIYANLAALPITS
>A0A3E2BZ90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
HSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHFRDLA
RKAGINVPIEAGVMPVVNANQVKRMTKMCSSKISEPVLAMIER
>A0A432TUK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thioglobus sp|TrEMBL
MKTSFEFFPPRTDKGKQTLAQVRQELSTINPEYFSVTFGAGGSTQDATLETVLDIQANDS
VSVAPHLSCIDSEKAKIIELLDQYKAADINRLVALRGDIPSGVRDIGDFHYANELVEFIK
SEYNDHFHIEVAAYPEMHPQAKNIQTDLEHFANKVKAGADAAITQYFYNADAYFRFRDDA
QKLGIDVPITPGIMPITNHTQLLRFSNMCGAEIP
>A0A4Y1X8M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes onderdonkii subsp. vulgaris|TrEMBL
MNVVDIINKAISERRTRFAFELLPPLKGDGCCGVFGSIDRLIGFDPAYINVTFHREGIKQ
AVRPDGSVEWHVVRRRPGTVGISAAIQKKYDVEVVPHLICGGQSKYDIEDALIDLDFLGL
HNVLALRGDKSQNEKFFMPHPQGHTHAVDLVRQIAAMNRGQFVDGEVEECHHSKFSIGVA
GYPEMHEEAASPEADIACLKAKVDAGAEYVVTQLFYDNARFFDYVRRCREAGITVPIIPG
IKPLSTVRHLTLLPQTFGCHIPEELGREVLRHKDDPKAVREIGTEWAVAQSRELVEAGVP
VLHYYPMGKADNIIKIAKAIF
>C0S8C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccidioides brasiliensis (strain Pb03)|TrEMBL
MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKARLERMSQALRPLFVTVTWGAGGST
VSKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTHAVDLVRYIRRMYGDYFCIGVAAYPEGHSDESHPEVQDPARDLPYL
VEKRKAGADFIMTQLIYDLEAYKRFEEMLRNHESGVFKTIPIIAGLMPIQSYHILTRTTK
LSHAKVPPDIMARVEEVKADDEAVKQIGIDILCEIVNGIKNLPCPGPRGLHFYTLNLEKA
VAFIVERCNLIPTSSEPSSDSDTELDSAVFITPGMKNGVPLISKRRASSLNSQPHNRLIV
DHPASLSIGAPSSQTSTTHETQALGAGMLALNPPHQSTALQISEGMGALGREATWDDFPN
GRWGDARSPAFGEIDGYGPSLHVNANVARQLWGYPTSREDINKLFHCHVSGELHIVPWSE
GGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSDHPIFGWGPRGEGFVF
QKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGTTGLDDAVPDY
SGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFRIWDEWRRIFRRGSPTEQL
LDQLKKDAWLICVVGQKFGAGCGGKEASEAEKFLWRVLAGKEDTEANPTGLY
>A0A133NQ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
QSEYGIKAVAHLTARYLNYDDVDEALELFDKAGVSGILALRGDVIEGQDAAGVFNHASDL
VAYIRTQRPDLPIFGACYPEKHPESATLQEDIDNLKKKVDAGVTHLISQLFYNNDDFLRF
RDLARKSGINVPIEAGVMPVVNANQVKRMTKMCSSAITEPVLAMMERWGSNPEVLQDAGS
IFASQQINDLVAQGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A3E2CHD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
LALRGDVIENQNAAGVFNHASDLVSYIHSKRPDLPILGACYPEKHPEAATLQEDIDNLKR
KVDAGVTHLISQLFYNND
>A0A1P8J5F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIANTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQESAGVFEHASDL
VYYIRSKHPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVKRMTSLCSSRITSQVSAMMDRWGSNAECLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A5C6E2M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novipirellula aureliae|TrEMBL
MTLASHYQSSRCAISFELFPPKTESGIEAMLNNVERLRSFDPAFFTCTYGAGGSTQDSTL
DVVEKVKKLTGLPVASHLTCVGSTVDQLAAFLQEAHRRGVDYLVALRGDPPKGSAQFEAV
EGGLRYANELVAMIRENFNHFGIAVAGYPEVHQEAVDAKTDLDNLKRKVDAGADVIITQL
FYDNADFYRFRDDCVAAGITVPIIPGVLPVTNFKQAERIAAMCKAAIPKSLAESMNQNDD
ADYQFNVGVEHARLQTIDLISNQVPGIHYYVLNKSEAAEKLLDGLELAAH
>G3C900|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pinus pinaster|TrEMBL
MKVIEKLQNAEKEGKVVFSFEFFPPKTEGGVENLFDRMDQMVEHQPSFCDITWGAGGSTA
DLTLDISNKMQNMICVETMMHLTCTNMPVEKIDHALTTIKANGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDMIKNDMGATEEDYQKDLAYLK
SKVDAGADLIITQLFYDTDIYLKFVNDCRQIGIKCPIVPGIMPINTYGGFIRMVGFCKTK
IPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMDKSALAILGNL
GLIDMTKIRRSLPWRPATNVLRTKENVRPIFWANRPRSYISRTISWEQFPHGRWGDTRSP
AYGALNDYQFLRRRSRSKKILEEWVVPLSSIEDIQEKFANFCLGKLTSNPWSELDGLQPE
TVKINEKLEQLNRKGFLTINSQPAVNGEKSDSPSIGWGGPGGYVYQKAYVEFFCSPEKLN
ALVEKAKNSSVVTYIAVNKKGATAANIGPTDVNAVTWGVFPAKEVIQPTVVDPVSFMVWK
DEAFQAWDQEWASLYPDGDPSRKILEEVQNSYYLVSVVDNDYIHGDLFSVFEEL
>A0A1M4E6W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea gerenzanensis|TrEMBL
MALGRPSIRPDRVPTVREMLASGGRSFSFEFFPPKTDEGERQLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERIAHDTTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVR
GDPPGDPMGEWVQHPEGVLYAEELVRLIRLAGDFCVGVAAFPYKHPRSPSIESDTEYFVR
KCRAGADYAITQMFFQADDYLRLRDRVAAEGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPDVAARFEAVKDDPAAVRRLGIEHGAELCQRLLDEGAPGIHFITFNRSSASREVFQRLE
QVPASA
>A0A2K1STR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MHYRPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLKDRTATARIAYTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDKAGVSGVLALRGDAVAGQEDAGVFEHASDL
VSYIRSKRPDLPILGACYPEKHPEAKSLQEDIDNLKRKVDAGVTHLISQLFYDNQDFLRF
RDLARASGIDVPIEAGVMPVANASQVKRMTTMCSSRITAPVYAMMDHWSDNADCLQDAGT
IFASQQINDLVAEGVDGIHLYTMNRPGVARRIWSNVKPLFTKII
>A0A3E2BZC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRG
>C0RZ73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccidioides brasiliensis (strain Pb03)|TrEMBL
MHIKDKLAYAEATGHPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPSEKVDAALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCEDQDDPELLMQHLKEKVDAGGTF
IITQMFYDVDNFLAWVKKCRDNGIKVPIIPGIMPIHTYAAFIRRSNWTKIQIPPGWLEAL
EPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVLDELGLIPSHETP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIQLWGKPKSLKELSEIFIRFLNGKLDRLPWSEGAVTEETDIIKRDLLD
LNSRGFLTINSQPAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNA
DLTYYCVNKTGELRTNTSDSPNAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHPASSPSRRLIQQVMDTWYLVNIVNNDFHRTHDIFDLFKNLKVKDLDLEVEPTDPAAE
FVGNIDHNGQSPEKLANGSAESKLQTITH
>A0A7H8KNL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora sp. NA04385|TrEMBL
MTLGSSSIRTDRAATVAELLATGRRSYSFEFMPPRSAEAEAGLWAAIRRLEALAPTFVSV
TYGAGGSTRGRTVAVTGRIAQETTLTPAAHLTAVGHSVAELRNILGHYADQGVRNILALR
GDPPGDPLGPWHRHPGGVEYAADLVRLIKESGDFCVGVAAFPEQHPRSPDRAADLRHFIA
KCRAGADYAITQMFFETDGYLRFRDDLERAGCATPIIPEIMPVTTVRSLRRIPQLSTAVI
PSRLSDALERNEGDPAAVRAIGIEFATEMCRRLLAEGAPGIHFMTMNFSTVTTEIYRNLG
LPGSG
>A0A672HBJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salarias fasciatus|TrEMBL
MVNQKQRVEGAWQSSKSDSSNSTSGGESSKESSRCSTPVLDADRSDRLRDKMRRRIESGD
CWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQTREVITGHLAKAKHLGLKNIMALRGDPMGTDWEEEEEGFNYAVD
LVKHIRAEFDSYFDICVAGYPTGHPEAESYEEDLLHLKEKVEAGADFVISQLFFRADTFL
KFLDDCRRIGISCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITEVIEPIKDNDAAIRNY
GIHQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELMNEESVFEVFTSYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELDKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVSALLKVLKKYEPRVN
YHIVNVHGLNLTNAPELQPNAVTWGIFPGREIVQPTVVDPVSFVSWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELINERCTDDLTAGEAV
EMVSIFKCCGASLIKHGGGYILKANIVNRS
>A0A6S7AE44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter animicus|TrEMBL
MRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRTLRNLGCDAAPHLSCVGASRQDLRDI
LQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANELVSFIRKETGDWFHIEVAAYPEMHP
QAANPSADLDHFVTKVKAGADAAITQYFFNADAYFDFVDRARAKGVNVPIVPGIMPITNH
TQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAFGVDVVTELCQTLLDNGAPGLHFYTL
NNSEAPLAIWKELTV
>A0A1L4CZG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Silvanigrella aquatica|TrEMBL
MTEVAVSLTPKLCCRSFRESLNKGECILLGGSTGTLLYEKGIFINKSFEEVNLSQPDLVL
QIHSDFINAGAQIISTNTWGANTFKLKAFGLENKFKELNIAGAKIARKAAKDQCWVAGSM
GPLGVRIEPWGPTSLEESKESFRHQAEALIKGGVDLFILEGFPDLSEIHQAILAIKELGD
SPIIAMMSVNEDGHSLYGTEPEWFIRKLDEWGADVVGIDGGNGPAPMLEILKKLAKSTLK
PIILYPNAGQPRMVDGRLIYMASPEYMGEFARQALLKGARLLGGSSGTSPLHTKIMSGAI
RQAKAFDTGQSNKRNIADHNPIRAHISTVPRTLQSNWSQKIADGKFVISMELLPPKGLEI
EKILERSKICKENNIDAINIPDGPRASARMSSLATACIIEREIGIETILHYACRDRNLLG
IQSDLLGAAGLGIKNILCITGDPPKLGPYPNATAVFDIDAIGLVNMVSRLNSGYDLGGSS
IGRPTCMSVGVGANPVASDIEKEKSRFRYKVEAGAEWAITQPVFDSASLFRFLEFSSQFK
IPIIAGIWPLKSLRNAEFMANEVPGVYVPKSVVERIRKCKTSDEQMEEGILIAKELIEEI
KSSVQGLQISAPLGMVDFALKLL
>A0A2N2K3Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-15|TrEMBL
MKEMSRLKAVLEKGGFAVTAECGPPKGADPDTVLRKGQLLNGKVDAVNVTDNQTAIVRMS
SLAACTLLKSAGMDPVLQVVVRDRNRIALQSDILGASALGIRNVLCLSGDHQSFGNQPQA
MGVFDLDSIQFVQTVRSMRDQGLVLGGDKLSRGPDVFIGAAANPFADPMAFRAVRLAKKI
AAGAEFIQTQCIYNLERFETWMGLVRDRGLHEKAFILGGVTPLKSAKMAKYMRDKVSGMD
IPDQVIERMEKVPPGKQREEGIRICVETVERLKEMPGVKGVHIMAIEWEDAVGEIVEKAG
LLPRPS
>A0A2N3G386|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium HGW-Actinobacteria-4|TrEMBL
MTIRELLNAPAATLSYELFPPRTPAAELALWDTIAKLATTAPDFASITYGASGSTRGTSR
AVVKRLAEEHTIPPLAHLTCVDQSRAEVTAVIEEFMAEGVRDFLALRGDPPAGQVDWTPH
PDGLLYASDLVRLIRDVAAAHGIDNLSVGVTAFPAQHAQEQWRQQGLDVLKAKQDAGADF
AVTQVFYDGAQWEALATDARAEGIGLPILPGIIALPNAARAARLEQLTGVPAPASTVDAL
LAAGEDPDAARAVGVATAAALARDLLDRGAPGIHIYTFNKHQAALELVKAIGHR
>A0A395VF79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia hominis|TrEMBL
MRLTELLKTDQVTISCELFPPKQGAQLANYKNIVADMAALKPAYMSVTYGATGGTSDYTV
ELASEVEKHQIPALAHLTCASSTKEKVASVIEELKEKQISNILALRGDIPQNADFPLPNQ
YRHASELIADIKAQGDFCIGGACYPEGHPEADTIFEDLDHLKEKVDAGCEFLTTQMFFDN
HILYNFLYKALSRGIDVPVVAGIMPVTNKAQIKRIVSLSGNMVPPRFLAIVDRFGDNPAA
MRQAGIAYATDQIIDLIANGVNHVHIYTMNKPDVAGEILDSLSEIYVRA
>A0A3N2R7K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Histidinibacterium lentulum|TrEMBL
MPAPAVSFEFFPPKTLEASFRLWETVQTLAPLDPRFVSVTYGAGGTTRKLTHEAVSAIHK
TSGLPVAAHLTCVDASREETLEIARGYAEAGVKGIVALRGDPPKGSGGFTAHRDGFASSV
ELIEALAEMNAFDLHVGAYPEKHPEAADTTADVAWLKRKIDAGATSAITQFFFEADTFFR
FRDACVAAGIDAPIVPGILPVENWKGVQKFAASCGTSIPAELCDSFEKAARDGRTDLLAT
VVATELCDELIRGGVEQLHFYTLNKPELTRDVCHALGVTPKSQLQEVA
>A0A1Q4CR83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium 65-51|TrEMBL
MTTPRISFEFFPPQTLDASFKLWETVQMLAPLRPTFASVTYGAGGTTRKLTHEAVTTIGR
NYGLNVAAHLTCVEATKAETLEIAAAYADAGVREIVALRGDAPKGATRFTPHPEGFANSV
ELIEALAATGKFTLRVGAYPEPHPDAADTLADVRWLKRKLDAGATSAITQFFFEAETFLR
FRDLCAKEGITAPIIPGILPIENFAGVKKFASRCGAQVPQWLDDAYATAKRDGREELLSV
ALCTELCDELISEGVEDLHFYTLNRPHLTRDVCHALGISPEVALEKVA
>A0A1J5C686|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium CG2_30_59_20|TrEMBL
MTSSTNFAVSVEFFPPKTPEGVEKLRVVRQQLYALNPEFCSVTFGAGGSTQEGTFSTVRD
ILSEGVSAASHFSCIGATRERVREQLGTLKAMGVKRLVALRGDLPSGYGTGGEFHFASDL
VAFIRAEMPDDFHIEVAAYPETHPQARSPEADLKAFAVKVQAGADSAITQYFYNSDAYFR
FLEDADALGVSVPVVPGIMPIASSSQLLRFSDACGAEIPRWIRLRLQSFGDDGASIKAFG
LDVVTDLCEQLRAGGAPGLHFYSMNQSESTLEICKRLGL
>A0A4V5NRH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila sp. IMCC35006|TrEMBL
MEIKTNSRLEKVLKNGHMAVSSECGPPRSSDPSGIIKKGHLIKNHVDCINITDNQTSVTR
LCSLASCIHLKNEGLEPVLQMVVRDRNRIALQSDILGAASFGINSMLCLSGDHQSFGDHP
SAQNVFDLDSMQLLQTVRYMRDEGKFLGGDEIKVPPNLFVGAAANPFADPFHIRVPRLAK
KIAAGAEFIQTQCVYNLEKFELWMKGVVERGLHEKVFIMAGITPMRSVGMAKYMARAVPG
MDVPEDLVKRLSGVPKDKQAEEGITIAVEAIERLKECTGVSGFHIMAIEWEEKVPEIVER
SGLYPRPVVD
>A0A2S0XJV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter sp. MSH1|TrEMBL
MNQYPLSRRSDIGNKIRVSFEFFPPKNDEMEARLWETVTRLEPLKPQFVSVTYGAGGTTR
ERTARTVKRILQESTLTPAAHMTCVDATREEVDQVIAEFAAMGVKRFVALRGDPKEGVGA
AYQPHPGGYANGAELVGALKAQGDFDISVSAYPEKHPESPDFATDFDMLKRKVDNGATRA
VTQFFFDNDLYERYVERARKAGIYIPIVPGVLPIHSFAQVANFSARCGAHVPNWLAERFE
GLDKDPQTHALVAAAVAVEQVLDLVERGVSDFHFYTMNRSDLVVAVCHMIGIRPQPVVQG
AAAA
>A0A2T6DJ74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutaceae bacterium EW11|TrEMBL
MIPDRPISQLFAQNRPLRSIEFFPPKDDEGVANLRDAAVVLKRIQPDFVSVTYGAGGSTR
ERTAQVATLLRGDLGYTVMPHLTCVGSTRDEIGQHADRIYGNGFRNIMALRGDPPKGQTT
FEPFKDGLRYASDLVALLKARHPDFCLGVAGYPEKHPEASNADADLSNLKRKIDAGADFI
TTQLFFDNDLYYRFVERCRNAGIKVPIVPGIMPVLSLKQIQRFTQMCGASLPSRLVKRLE
TAGDYADAVEAVGIDWALTQIRDLISRGAPGYHLYILNRAKSAVALAAGLAA
>A0A5R1NH77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMB1-7|TrEMBL
MTATPTTPPADPDCRSSIPFSFELYPPKTDAATTALHATIDALAAARPKFISVTYGASGS
SRTSSLDVLRYIRRATIVDPMAHLTCVGSSHAEASSLIREFLDAGVSSFLALRGDPPEGL
TENDAFLGDLHSAGELVQLIHRVQAERVPYQETPIPGLPRARAVKTEREHVRIAVAAFPN
GHPRSRSTAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPV
TSPGRLLRILELSGEELPAELSIQLEVEPTLEGQREIGISHAAALAEKLIAGGAPGLHLY
AFNQHETVLAVLDRAGALAPAQPVVSAHNPPPTHPSTSPADTRAGIHSTKDHY
>A0A2N3AK08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium HGW-Atribacteria-1|TrEMBL
MNLREKLAANKFVVTVELDPPKTLNLERILTEVNSTNFRKLVDAVNITDCPLAKLRMSPI
ALSHIIQEKIGLEAIFHITCRDRNLLGLQAELLGASALGVR
>A0A0Q6B7A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilus sp. Leaf416|TrEMBL
MNNKTSFSFEFFPPKTAEGMANLRLARAELAKFSPEFFSVTFGAGGSTRDRTMETVLEIQ
AEGYGAAPHISCISSSKEEIRELLQTYQSKGIKRLVTLRGDIPSGEVSAGDFKYANELVS
FIRAETADWFHLEVAAYPEFHPEASSAQKDLDNFKRKIDAGADSAITQYFYNVDAYFRFV
ELAHKQGITAPIIPGVMPIYNYTQLARFSNVCGAEIPRWLRLRLEAYGDDIASLRAFGVD
VVTDICAKLSQAGVDKMHFYTLNQAGIIGQIIRQL
>A0A7W7YGM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecobacter dejongeii|TrEMBL
MHIKDILLAAKRPTLSFEFFPPRTPESVKELQDSLQQLAVWRPDFVSVTYGAGGSTRDRT
QALVGELSQSDVFDPIPHLTCVGHTRAQIRLLLENYAAAGVSNLLALRGDLPGQGAQEGE
FKTAADLVRFIRQFNELGLHPDPRGFGIGVACFPEGHPGTPNRMLEMDYLKAKVDAGADY
LCTQVFFDNHDFHDFRARCELAGILTPIFAGILPLTQLSSLRRMAELSAGSRYPARLLRC
FQRAGDDAESFRQVGIHHAITQSADLLDQGVSGIHYYTLNKASNTVQVLRGLGYSGHHSL
SKVIQK
>A0A2P7YHR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] pseudohaemulonii|TrEMBL
MSTVLSKIQALQPGERFCSFEFFPPKTDAGFRNLLARLSRMMALNPLFLTITWGAGGSTS
EKSLDLAATCQKELGVTTVLHLTCTNTNKEIIEDALKRAREAGIKNILALRGDPPRAEEY
WTPNCDFNSAVDLVRFIREQHGDYFCIGVAGYPEGHVEGADALDQDPRKDLPYLIEKVEA
GADYVVTQLFFDVDKFVAYEQLLQETPQLKNIVLIPGLMPITTYRVFIRSTRLSHASVPK
AILDDLDAHANDDDMVKVIGLDVLTKMILEIDARTNGRVRGYHFYTLNLEKAVASIINRL
PVLQNMIPHNQLVQHDDAIASDSDDDLPVVPQKNGRRKSSVNENLVAVPGVAEAKRALVS
KALSKDPKAIVDISTGKGALGKDATWDEFTNGRFGDSNSPAYGEIDGYGPNLKLHSNKEV
EETWGEPKSVSDITKIFVDYLSNKINVLPWADSELSPETALIQEELFELNERGWFTLASQ
PAVNSCSSRDKILGWGPPNGHIFQKSFVEFFIPKKQWHDDLLPRLASQVDDKTITYYCGD
ASGHISLNLPLSIGKNSNSKLAVTWGVFPLKEVLQPTIIDYESFKAWNEEAFLLWLEWAR
CYRKDSASFQLLNDIYSSYYLVSLVHHNFTDEFVLWTTLLSD
>A0A290HSK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurospirillum sp. JPD-1|TrEMBL
MIDSFIEKLKYDTFLTLETTPMHEPTFEPIIEKIAQFGLDKKVDGFSTTDNPLARLKFNA
FFGALKLQTRFTKPVITTMSMRDRNKVALQSDLLGANAYDLRTILCLTGDPASASDQPAV
KGVFEGNSTLLLEIIQCFNAGIDYSGKPFKTQPKPIYPFAVCNAHANTPKNLMKKMATKI
EHGAVGIITQPVYSVENATMLLELLKDAKSAANKEQSHTQLILGFFPIVKLRTAQFLAAH
VPGIYVPPLWMEKLAKAKKISEEEEKKVGFELSRNAFLALKKVHPKIHMMSANNFELVAD
LLQS
>A0A013VEF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. Ant17|TrEMBL
MTLNDPVAPLYADLAGDCHVSFEFFPPKSEKMEAQLWSAIETLTPLAPKFVSVTYGAGGS
TRERTHNTVARIARETPLAAAAHLTCVGASKAEIGEIADAYWDAGVRHIVALRGDPPEVG
GSFEPHPDGYKGAAELVEGLAQRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGAIR
AITQFFFTPDAYFRFLDKTLAAGITADIVPGIMPVSNFAATQRMAAMCNTQVPNWMARLF
EGLDDHPASRQLVSATIAAELCQKLYTGGVRDFHFYTLNRSELSFAICHLLGLRAKPAAN
A
>R6EI78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:65|TrEMBL
MKIRDILNKDTATISFEVFPPKKSTDFGNVEAAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGEIQKQHNVPTVAHLTCVCADRGSIGTALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKKNGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIVPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNLSEILKA
>A0A1L9TGC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus sydowii CBS 593.65|TrEMBL
MHVSEKLSQNEAAGKIGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDVTWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQERVDAALQAAYKAGCTNILALRGDPPREKET
WEATDGGFRYAKDLVKYIREKYGNHFCIGVGGYPEGADDNSDVDLLIDHLKEKVDAGSTF
VVTQMFYDTDNFVQWVQKCRAKGITVPIIPGIMPIQTYAAFIRRANWTKTRIPPDWLEAL
EPVKNDDAAVKQIGKRLIADMCRRLIDSGIKHLHFYTMNLAQSTQLVLEDLQLMPTAETP
IPRPLPWRPSLGLNRREEDVRPIFWRNRNSSYIARTQIWDEFPNGRWTDSRSPAFGELDA
YGVGIKGTNEQNIKLWGEPKSIRDLADVFVRFVEGQLDRLPWSDSPITSETNAIKDPLVE
LNKRGFLTINSQPAVNGVKSSHPIYGWGPKNGFVYQKAYLELLIPAYLIDELISRIEANE
DLTYHAVTKHGELRTNTRDSPNALTWGIFAGREVVQPTIVETVSFLAWKDEAYQLGEDWA
KCHDSASSSRKLLQSVMDSWYLVNIVNNDFHNTYDLFELFKDLNVKDIDAEFAGENPEPK
VQNGTTNGTTNGTTNGTIPEQPVKN
>A0A246K2N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis bauzanensis|TrEMBL
MTSNLNSLAEARRAAASPLFANLDGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLAPRFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASRAEINEVAEAYWEAGVRHIVA
LRGDVPGGAPYSAHPEGYANAVELVAGLKAVAPFEISVAAYPETHPDADCPQADLDNLKR
KLDAGATRAITQFFFSPDSFLRFRDKAAASGIDAPIIPGILPVSNVSQTRRIADMCGTAI
PAWMVSLFDGLDDHPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVSSAKDQAA
>R5GTE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. CAG:755|TrEMBL
MKITELIAANDRTAFSFEVLPPLKGTGIGTLTRTIDKLREFAPSYINITTHRSEYVYKDL
GDGLMQRSRLRRRPGTVAVAAAIQQKYGIPVVPHILCSGFTREETEYVLLDLQFLGISNL
LLLRGDKARDDASFKPTPGGYAHTTELQAQINRFNAGFFDDGTPIKVPGEPFSYGVACYP
EKHEEAPNMGTDLHWFKQKVDAGAEYSVTQLFYDNTKYFAFVAAARQAGITVPIIPGIKP
LTKRSQLTVVPKVFHCDLPEPLVNEALKCKTDEEVAQVGREWTIAQCRELMKAGVPSLHF
YTVSAVDSIAEIARAIY
>A0A2P5XFY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium barbadense|TrEMBL
MKVIEKIQSLQEGKAVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNELAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGVKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQYPYGRWGDSRNPS
YGALTDHQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSYCLGKLRSSPWSELDSLQPET
KIIHEQLGNINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGTTDVNAVTWGVFPAKEIVQPTVVDPASFMVWKD
EAFEIWSRAWAALYPEGDPSKKLLEEVQSSYYLVQSSYYLVSLVDNDYIGSDVFAVFGDL
>A0A2S9IXF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium phragmitis|TrEMBL
MSVFGLSRRPDIGQTTRVSFEFFPPKTEEMEKRLWETVTRLAPLKPEFVSVTYGAGGSTR
ERTARTVARILNETDVTPAAHLTCVDATKEEVDTVIREFAALGIKHFVALRGDPASGVGD
QYRPTPGGYLNGAELVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPILPGVLPIHNFKQVTNFCSRAGTHIPAWLTERFD
GLENDPQTHALVAAAVAAEQVLDLVERGVQDFHFYTMNRADLAFAICHLIGIRPQKQGAE
AGTGKSLSPDLAGAAA
>A0A831T192|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MKIKEMFGRGYPVFSFEFFPPKTEEGIPVLQQTIRDLVALRPSFCSVTYGAGGGTRERTV
DLVCFIKNNLRVEAMMHLTCVGHSRDELRRILDNARDRGIENVIALRGDPPKDQKVTGHN
REIMVADYQPKDALRGDPPKDQKVTGHNREIVVADYQPKDALRGDPPKDQKVTGHNREIV
VADYQPKEFKPHPDGFRYAAELVSLAHSYGCFCICVAGYPEGHVECPDKEEDLRHLKEKV
DAGGEVIITQLFFDNRDYFNFVERARALGIQTPIVPGILPILSVKQIKRFTQLCGAKIPA
DLEEKLRQVETDDEAAAQVGIEHATRQCRELLERGAPGIHFYVLNKARSVKAIFYNLGLA
RKAAT
>A0A2V7P070|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
FILETFSDVDELHEGLRAVRSLSDLPVIAQMTIGDDGLTHYGTAPEIFTKQLAEWGADVI
GVNCSVGPAGVLEAVEKMVKVTDRPISAVPNAGLPKDVGDRKIYLASPEYMASYARRMIE
AGARIVGGCCGTTPEHIKKIRDYVASVVPRHQPVVVSREVVAAPAGVAAVPLAQRSRFGT
KLARRELVTSVEIVPPKGVDPAPMFAQCRALKAAGVDAVNVPDGPRAQSRMGALLSSVII
EREVGIETVTHYSCRDRNLLGMLSDVLGASAAGLRNILIITGDPPKMGPYPDATAVFDID
AIGLTNLVYRLNHGLDPGGNPIGKPTQFAIGVGVNPAATDLDRELSRFAWKVDAGADFAV
TQPVFDIAQLESFLKRVEQFHIPIVAGIWPLLSLRNAEFLANEVPGVSVPDTVLARMRKA
SDGGKDSALAEGVKIAREMFALVKRDVQGIQVSAPFGKVEVALEVFK
>A0A7X3ZFA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MINPDTLGTDLISRGQDVIIHLSCKDWNRNALQGRAWQLASEGFNNILALSGDYPISGYQ
GTAGGVFDLDSVGLLEMFAAMNAGLKMKKGKRTQRMEATDFYLGAVVNNHKRYEREVMPQ
YFKLAKKIHVGAAFVISQIGYDARKQDELLKYMALCGLDVPVIANVYVLSRPAARFFHKG
HIPGVEVTDELMAVVEKQAQANDKGRAFFLELAAKQCAIAKGLGYRGAY
>A0A2E6CFH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MSSFLQYLQDAPLLCDGAMGSLLFERTGRLSEQNHLYETFNADNPDLIRDVHLEYLQAGA
TTLITNTFAANHTHLAIHDQADRVEELNRHGVLVAREAIEQYNPKRSRDDPFFVIGSIGP
TLEVRESPQEVRAVYKPQIXALVGAGVDALLFETFTSLLHVSAVLDVVHSLSKSVPVVVQ
MSLHQXXNDSWDLDPLLFAKTAVDLHADVLGVNCCAPWEAXXFLKTVSELESVKAGQIQL
SLMPNGGDFQRIGHRYLTGVNPEFMGRFARQSAQCGAHLLGGCCDVYPAHINEMHNYXRS
LHKTQIQSQIAWDHAGEPTPIEIKRDNGPFSQKIFNKEFAISVELLPSRGTGGIKARMQF
IQDLAASGLADALDLTDGSRGIPLMPPGDFIHLIRHRLGWKADDELELIPHFTLRDLNTM
GLQSRLIGYWANRIHNVLLITGDPPKMSPTYPRSSAVFDMDSATLIRYVQEFLNAGIDFG
GQKLGSHRDPRTRFTVGTGFEPEALDXESETEKLQRKLEARVDYIMTQPVFNHAALDTLA
PFREQSAVLIGVLILANAAHARRMAAVPGMVVPDEVLERLARFDKAEDQAAAGAELAAEQ
VQRIRREGWSGVYLMSPASHNRIINVLREGMG
>A0A1F5DH63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon RBG_13_38_9|TrEMBL
MIREAFSELTKAIQAGTFVYTGEIEPLKTTSLEETLETAKILKGHVIAANITDNPTAFAY
MNALIPSYFIQKEIGLEAVYQVTVRDRNRLAITADLLAASALGIKNVLALSGDHTTVGDD
PGTKPVYDLDSTALVDLLRKMVDDGTDIKGNKIDQPPKFNFGIAGNPNADPLDPEILKIE
RKIELGADFIQTQAVYDIDLMKEFVKQVSRLKVPVIVGIAPFKSRGMMDWMVKNVPGIVV
PEDIQKSLLAAREKSKQAFLDENLKIFGDLIKEIRNTPNVSGLHIMTIGFEWIVPKLIEK
ANQ
>A0A840TGZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhabdobacter roseus|TrEMBL
MTKVTEYVRQAGGRTLFSLEIIPPLKGQNINQLLDSIEPLMEFKPPFVDVTYHREEVIDK
QLPNGLIQRIPVRKRPGTVGICARLMERFKVDAVPHVICGGFTREETEDMLIDLHYLGID
NVLVLRGDAEKSVGVFMPKAGGHCYASELIEQVVSMNHGKLLHEETEGTPTNFCIGVAGY
PEKHLEAQDLDTDFRYLKKKVDAGAEYIVTQMFFDNQKYFRFVERCRAEGIQVPIIPGLK
PLSTKKQLSILPRIFHLDMPPELVAEVEKCDTDQQVRQVGIEWGIQQCRELLAYGVPVLH
FYTMGKSDNVLQIARGVF
>A0A3M1FXP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineae bacterium|TrEMBL
MHPFLQAISERPLLSDGAMGTMLFAKGASTDQCLEYLTVSRPQWVTEIHQAFAAAGADMI
KTHTFGSNRVRLAHYGLEHKVRDLNFRAVKLVRDVREVVGRALFIAGDVGPLGDRLAPYG
PVTLDEAQEAFQEQALALWEAGADLLLFETFSEIAELEIAVAAARSVCDLPIVASMTYNQ
DGLTGSGVTPAEAVHRLRQAGVDLVGVNCSVGPAPTLEVLRAMHAAEPDAPLSCMPNAGF
PERVEGRFSYPAGPEYFARHVGPFLDNGARLIGGCCGTTPMHIRAMRQALDERLGGQPTR
SRVAVTAEAELPAMHVALDTVAEDEERQETELLRKIRAGKFVISVEVDPPRGFNAQKQIE
GARHAKSMGADAINVADSPMARVRMSALALCVQIQQQVGIETIVHFTTRDRSLMGLQADL
IGAQALGVRNILALTGDPPSLGDSQNSTPVYDVDSIGLVRIISRFNEGFDLAGRKMGQPG
NFTIAVACDPTRPNLEEEADRFHQKVSGGAHFTMTQPIYDPEVWLRFLRVYEERHGEFPV
PVLIGVLPLQSHRHASFLHNEVPGITLSEEALERMRKAGADGREEGVKMAQELLLQLVEA
PHVQGVYLMPSFGRYEVACQVLEVLTPEQRGMGVR
>A0A2E5ULF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MNSPKDTLRSLFADGNVHVMDGAMGTEIYARGVFVNLSYDGLNLENPSLVHAIHKDYVNA
GAEIIETNTFGANPAKLSAYGLAEKTELINKTAAKIAGKAAGNNAHVLGAIGPLGVRIEP
FGPTAKEEAQELFTRQIVGLMEGGVNGFILETFSDLNELEQAFLAVRAKSDLPIFCQVTV
GEDGSTVYGTSPEAVATEVSDWGADVVGVNCSVGPAVMLDVIERMVKVTDRPISAQPNAG
LPRIVGDRKMYLTSPTYIGQYARNMTDAGARFLGGCCGTGPDHIHRIKESLGKMPPLSGI
QVERVSSITENESSFELATPLAEMSQFGRKISEGTFTTSIEISPPKGPDPSEMIDQCKLI
EAAGADSINILDSPYAPGRMSSLPAGIIVEKEVGIETVVHYPCRDRKMSRMISDLLGASA
SGISNLLLVTGRPPPTGPYQPALSGIDIDSIGLTNVVTGLNKGIDPGGNKLTHRTNFVIG
VRMNHLAMDQEKEISRLNWKVDAGVHFLTTHPIFSTEKLKQFLEGIPDFKIPVIGTLWPL
RSFREADYLHNEVPGIQIPKTIFDRMERAERKGDVEAKAEGSRIARELFDAMQPLVAGLQ
IKASEQNFGEALNLLNKVKNI
>A0A848XS76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTDFRALLEDGRVHVLDGAMGTMLYARGVFVNVCYDELNLSHPRLVADVHEQYIRAGAEV
IGTNTFGANPVKLASYGLEERAAEINERAAAIARDTGAGRAVVLGAIGPLGVRVEPLGPT
SLEEARDFFRVQAQGLASGGVHGFALETFSDLSEMEQAFLAIRQVSDLPVLAQVTVGDDG
LTSYGTSAEQAGARAESWGVDAVGLNCSVGPAVILEALERMAEATNLPLVAQPNAGLPRV
VGDRKMYLAGPEYMAQYARRLIQAGARFVGGCCGTTPEHVRQIRESVIALQPRTPAVRVT
RTVGSKEVRQEPVPLENRSRLGRKLKTGEWVTSVQIRPPRGWDAAGLVADCRRLATSGVD
AVTLYEDRGASRLGVMAAARLVLQSCAIEPLVHYTCQSRTLLDMISDLLGAAAGDVRNLL
VLSGDPPAGAPYREYASVIDVDSIGLINVISGLNAGIDPSGNEIGRPTEFVVGVAVNQGA
RDPAREAGRLYWKADAGAHYVVTQPVFDAEHLFGFLDGVEGVDLPILAGIWPLTSARQAE
YLQNEVPGVYVPPSVTERMRTADSQGPESAAAEGLALAREVASEVRARVQGLHVVAPDGR
LDPALAVLRSSR
>A0A7C3B949|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineae bacterium|TrEMBL
FERWLEELDKRNLLGRAYILAGVAPLRSAHAAHYLNDHVPGIIVPQAIIDRLERAADPAE
EGVQIALEIIDRLRHTPGISGVHIMAVGWESIVPRLIRDSGIERLTARLACEDEQTQELM
HITLEKENGDNGQRPFEL
>A0A0C5WAH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Siansivirga zeaxanthinifaciens CC-SAMT-1|TrEMBL
MKVTDHIKKANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYID
KGNGLLDKRITRMRPGTVGICASIMHKYKVDAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VMALRGDSRKDEPYFIPTKDGNAFASELVAQISDLNKGKYLHDNVEIEHKYDFCVGVAGY
PEKHMEAPSLQNDLKRLKAKVDAGADYVVTQMFFDNKKYFDFVEKAKEMGITVPIIPGIK
PIAVKRHLQILPQVFKIDLPEDLIDAVEACKDNNAVRQVGIEFAIQQSRELKEAGVPFLH
YYSMGKSDNIKAIASQLF
>A0A5N7ZQE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp|TrEMBL
MSDSISPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGSSRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVRKVRAGADAAITQYFFNADAYF
DFVDRAQAKGVAVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPMAVWKELSA
>A0A3D2SWV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
DPAGNSIGDPTKFVQGVVANPGALDLEREVTRFRYKVEAGASFVVTQPIFDPESLERFLD
KIHQWKIPVVAGIWPFLNLRNAEFLANEVPGATVPEKIVDRMRRAQISGDEEALNEGVEI
AAEMIDAVRPLVQGFHLSAPSRRVDVALRVLDEAGVSTNT
>A0A1Q7FFQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium 13_1_40CM_65_17|TrEMBL
MGLNDETSRQSLIGLLRAPRYEVLPTDDIEQLVLTHVPHDVTMTITASPRRGIDATISLA
ERLAKHGYHVVPHISARLIRDDAHLREVLARVDALGRGEVFVIAGDAKEPAGDFPDSVLL
LTAITAETHGLREIGVTGYPERHSFIEDDLTIQAMWDKRRIATYIVSNLCFDPRIVKKWV
ARVRRRGVQLPIHVGLAGVAEPAKLLRVSTRIGLADSARFLRGHSNWFMRMVQPGGYDPE
RFATGLLPDLAAPERRVVGLHFFTFNEIEATERWRQDALSRLLVA
>A0A2E0TCW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sandaracinus sp|TrEMBL
MKVTEHLERATRPLISFEIIPPKRGGNIHDLLGLVEELCHHEPPFIDITSHPAEVVYEET
PDGIQRHVKRKRPGTLGVCALIQNKFNVDAVPHVLCHGFTQQETEDFLIELRYLDIDNVL
AIRGDDKGYRKPLRDGRTRNVYAIDLIKQISAMNQGQWLDAHMDSSATDFCVGCSGYPEK
HFEAPNLAADVRRTKEKVEAGAEYIVTQMFFENRHYFDYVKACREAGITVPIIPGLKVLT
ARRHLRSIPSVFHCDIPEALSREIEAADKKHVFDVGVAWAVQQVRELLEGGAPSVHFYVM
QSAKAVNAVLAQIDI
>A0A2I1NAW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter ureolyticus|TrEMBL
MFFEKLKNNESGILLYGQTPPKQNHQNLENLLELRQKRLNTLDIDGIVIYDLQDEGDRND
EKRTFDFVKTINPYEYYKSLELKFPGIIYKSVGKYNQDEFIKGLKFDKNIANVFVGASSK
DQKIKLSLKKAYEIKKEFAKDIPLGGICIPERHEIKHNEHLKVANKTLNGCEFFITQAVF
NAINAKNFIDDYAKLNIKKVPIIFTFTPCGSLKTLEFMKWLGISIPPFLENRLKNSIDIL
QSSVSLSFEMFEFIYRYAKNKGVVVGANVESISTRKVEIEASIKLLKDIKRSIDRKV
>A0A522NA75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MPRRSLESRRRPTEHAATILEDLRNGLLLADGAMGTMLIAEGAAPHKCLEARNLEQPEAV
RAIHERYVEAGADLIETNTFGANALKLADFSLEYRLTEINAAGVRIAQLAARSAPRRVYV
AASVGPLGKALHPYGTLTEEHAFEIYREQCAALAAEHPDAFALETLTGISEARAAIRAAK
EAAPGIPRICTLAMLEGGQTQYGEDARETLHALVEAGADAIGLNCALGPAQTYEILAPIV
SEFSVPLVAAPNAGFPGRLHGRTVYFSSPDYFAEYAGSFAGLGINLIGGCCGTTPAHTAA
MRAALRAAVLGDRRATHVVSVQDYERPVPITPARRRNAFEERLGQTFVITAEIEPPRGID
FRAQLAGARVLEEAGVDAVDLTDNQRAQLRMSPIALASLLMQHTSLATILHFSCRDRNLL
ALQSELLGAAALGITAILALTGDPAAFGDYPVATGVYDVTSVGLVGILRALNEGKRHGGI
DIGPPAAFKIGVTVNPLARDLDVELARFRQKITGGAHFALTQPLYEIDALKRFVTELERA
EIPPIPILAGVLPLRSARSAEFLHNEVPGMFVPLPIRERMRRAGEDGAREGVRIAQEFLR
EARALIGGAYVIPMGRYQEAAEVIAPIAAMR
>A0A6L3AA21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MRFADRLRSGQFAVALEITPPQRPLQSVLLRRASALGHCADAVNVIQRPGRQSSLDASIS
LLRTGIEPVWHLVTRGASRGDIARDLVSAREAGIGQILVIRGDHATHDLPDTPAIREAIG
LAREALPGALIGATFNQYAPDPGAALRNLLPKLRAGADFIQTQPVFDPQ
>A0A341BS35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neophocaena asiaeorientalis asiaeorientalis|TrEMBL
MDRPKPRVLPAGHCCPSLGMRAWEAGSARFSVPPSISRSSAMVNEPRGHGGPSPRWESSS
SGSESSKDSSRCSTPVLDPERHERLREKMKRRVESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKRLGLKNILALRGDPTGDQWEEEDGGFNYAVDLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEAGLKHLKEKVAAGADFVITQLFFEADTFFRFVRACSEIGITCPILPGIFPIQ
GYRSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQALSLCRELLASGSVPGLHF
YTLNREVATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGW
GPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGDNITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRTIIQHIHDNYFLVN
LVDNEFPLDSCLWQVVEDTFELLSGPPQSKRETEAP
>A0A7V2HZK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MNCNKLEIIFTVIPPPLEWDISKIERKAFEVANITKILDIDFISLPEVIEERSRGQRIIP
YKMKFDNVEFGKMIKNFDNSVEIIVNKISVIMEKEEFETWIKENSKGFNYLLIVGGESSK
IKYPGYHPIPATLIAKNYFKNVYGITIFHRKDEPKKLLEKTKAGMKAFISQIVFELENAK
KVIYEYFKLCEEENIKTSKIYISFAPVSQRKDLEFLKWLGVYVPKEIENYLLEDEKKLEK
RSIEIIESLFQELCFLNIENIGINVEHVMYNNLQVAAYAVHRIKETWKWRN
>A0A7V4YRA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
SRFGELLKKKDHFIICVEVDPPFGISHEKELKAVTELLKGKIDAVNIADGPRAMARMSPI
ALGKLIAEKSDVEVIIHYTCRDRNLLGIQMDLIGANALGLRNILAITGDPPKMGDYPDAT
AVFDIDSIGLIHLIQNLNRGLDFTGKFIGEATSFVVGAGCNPGAVNFDYEIERFKKKIQA
GAEFIFTQPVYEPSLLEKFLDATKEFSHIPIIVGILPLASYRNAEFLHNEVPGMQIPPQI
MERMAKAPSKEAQREEGIKIAKEMLSYLRKVERVKGVYIFPPFGRYESVLRVLE
>A0A0F2SAZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium BRH_c23|TrEMBL
MLNKFKESILDKNTLSVTWELVPGRGANEKAQESAIASAEQAAKGGRVHALTITDNPGGN
PAILADYLGMEILKMGIEPLVHFTCKDKNRNQMESQLYALDRAKVRNLLVMTGDYTYSGF
KGRPKPVFDLDPSNTLQLIAEMNKGLEVQGMKGPTYHAPSDFFAGAAVSPFKSTEAELMV
QYYKLKKKIEGGAQFVVTQLGYDARKCHEVIQFLKVNKLDIPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNEEKGAADKGVGQRMLRAAKLYAILKGIGCAGVHIGGHNLKYEQ
LEYILDKGEELYPNWQDLVKEFDYPQTNGFYYFEKDEKTGLNTDRPTNRANLPLDAPAGA
MYSLMRGMHGLMFTPDKKLFPMMRSMYRAAEGKKKTEKRLHAVEHLAKVVMLDCKDCGDC
AMLDLAYLCPMSQCPKNQRNGACGGSLDGWCEVYPKEKKCVWVRAYARLKKYGEEASLDV
PPVPPANWDFYQTSSWSNFFLGKDHSAPILGIKRPESKLKK
>A0A4Q9VUG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Siculibacillus lacustris|TrEMBL
MTSPSPLPPRPRLSFEFFPPKTEKMEAGLWTAIEALAPLAPAFVSVTYGAGGTTRERTHD
TVARLVRETGLKPAAHLTCVGATREEVDAVVRAYAGVGVGHIVALRGDPPAGVGAAYAPH
PGGYAYASDLVAGIAAIGGFEISVGAYPERHPESASWEIEIDNLKRKVDAGASRAITQFF
FDNDLFEGFLERVTRAGITIPILPGIIPIHNFTAVAGFAAKTGASMPAAVAARFAGVGEE
ASARARAAIDFGRVQVADLRRRGIADFHFYTMNRADLVVGIVEALGITAGDRVG
>A0A090DH38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. ORS 3324|TrEMBL
MIAPQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>L8IXC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos mutus|TrEMBL
MDRPKPKVFPVGHCCPSLGMRASEAGSGRLSVPPSISRNSAMVNEPRGNGSPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>A0A4R6F1P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. BL10I2N1|TrEMBL
MNPIELSFEFFPPKTQEAVDKLRATRAQLTPLKPKFVSCTFGAGGSTQQGTLDTVLDIAK
DGIEAAPHLSCIGSSKESLRAILNEYRSHGIRHIVALRGDLPSGMGEVGELRYASDLVSF
IRSEFGDWFRIEVAAYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGLDV
VTNLCQRLVDAKVPGLHFYTLNGAAATKAICERLGV
>C7NEN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia buccalis (strain ATCC 14201 / DSM 1135 / JCM 12969 / NCTC 10249 / C-1013-b)|TrEMBL
MKIKDLFEKKERLISFEIFPPNKNFSEEKLKNVTAELVEYKPDFISVTYGAGGKTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEIHDYLQEAKSKNIKNILALRGDVPQGETEEIYD
KGDYKYASELISDLRKNSEFNDFSIGGAFYPETHYENNDLVDLFHLKNKVEAGTDFLASQ
MFFDNDVFVKFKEQAEKLDIKVPLIAGIMPVTNAKQIKRIIELSKCSVPEKLDKLLEKYG
DNPESMKKAGIMYASEQIIELLAYGIKGIHIYTMNKPEIAKEIMKNIEFAR
>A0A1N6UVX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter lucknowensis|TrEMBL
MKVTEHFQNANGKTLFTFEILPPLKGENMKTLFSHIDPLMEFKPPFIDVTYHREEYVYKQ
RENGLLEKRSTRKRPGTVGICAAIQNHYKVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLVLRGDCVKSEQRFVPEPDGHTYATELIGQVVNMNKGCYLDDEQAYHNGTDFCIGVAGY
PEKHFEAPNITSDLRWLKKKVELGAEYIVTQMFFDNQKYFDFVKRCREEGINVPIIPGLK
PMTTKTQLTLLPSLFHIEIPCALADAIEVCPDNKAAAQVGVEWAIQQSKELMEFGVPCLH
YYSMGKSESVRKVAEALF
>X5ZN40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNJC395A00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A399RID1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Henriciella algicola|TrEMBL
MSHLSVATRQAEERPRVSFEFFPPKNETMDERLWECVRRLEPMQPDFVSVTYGAGGSTRE
RTHDTVARIASETSLIPAAHLTCVSATKEDVLQTAEDYWEAGVRHIVALRGDSPDGMGAE
WKQAPGGFQNVIELIESLRAHRPDLGKVFEVSVACYPEPHPDTRGWEFDLAHLKAKQDAG
ADRAITQFFFEPDIYFEFLDRARNAGITMPIVPGIMLQPNFNGLKRIAGLCGASVPDWLH
KLYEGLDDDADTRDLITANIAAELCHKLADGGVTQFHFYTLNRANLALSTCHLLGLKPAT
AEAA
>A0A4R1ZUU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. BK033|TrEMBL
MLKDKILNRQAGIITYGMTPPKSSHTPEKLAEISEKQYERLKNLDIDGLILYDVQDEADR
TDEERPFPYLEALDPTSYSKNYLNYWKVPKIIYRVVGNNSEESFAEWLKQDAEEDRFSVF
VGTSSSKQQTTMKLPEAYELSKKLNDRLTLGGVVIPERHMKKNDEHLRIREKVDGGCKFF
ISQATFNVEASKNMLSDYYYYCQEQGIETVPILFNLAPCGSQKTLEFMKWLGISIPKWLE
NDLIKSTDILDKSVALSLKIFEELFEFGIEKGIPIGCSIESVSTRKVEIEASVQLVKDIK
TMIDRKLGVHAIV
>A0A1C5FWB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MnatMP-M27|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRAELRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWISHPDGLDYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIGHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATELCARLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>A0A0A2BKQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus sp. MIT 0601|TrEMBL
MPSYKPINFILGKLGCLISDSNYLIRKQLNSVLENALNSEGAAITAEIMPPRGGDASKAI
DIASNLAGRIHAFNVTDGSRAIMRMSSLAVCKLLLEAELEPVLQIACRDKNRIALQAELL
GANALGIKNVLCLTGDPVRVGDQLNARPVHDFESIQLLKQVSAFNKGKDPVKGELPDGQT
RLFAGAAADPNCKSLNSLMKRLERKKNAGAHFLQTQMVMDPRVLERFCKEVATPLELPVL
AGVFLLKSAKNAAFINKVVPGASIPETIIQRLNDSSNPLEEGIAIAAEQVKSFTGIAKGV
HIMAVKAERLIPNILDQANLKITTKQIQ
>A0A1C7NXZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararhizobium polonicum|TrEMBL
MAHIDENPLGRHLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VTNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNGKFLSGRKLTTPPQVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMNKVRDLGFDEKCFILVGV
GPLASAKTANWIRNNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIKGVSGVH
VMAYRQEEYVAEIVHESGVLKGRTPWTRESNPGDSRVAERLDAIRDGKQENQEEMADVAA
HRPH
>A0A1T1GRE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 5600|TrEMBL
MSLFSQYLLQRQFCISFEYLTTQKPHCVPTTFAGFPVCMTLADRVQSDTDIAPLEAMQDY
PQSIEKILHYSGKGRDISDFQAFLKDAQQHGVENLLLLSGDKLKQHQDGANDPSLRSRYL
ESVNQVMAAKDFGGFYLGVAFNPFKYAEAEKDAQYFKLNKKIQAGADYVITQLGFDMDVL
SSYQHYMQQYYPHVPVLACVMPLTFTRARFMAKQKVAGIVLSADVLNFLQQEQQTDAIQA
EQNVYARCALQILMCQHLGYAGVHLSACHKAEEQEKLQKAILQFATLTFEQCLAKWKMLW
RSSVEVNFQPTGANNHKAPVEQVLKYKSMHVMHELFFSSKLAKGAGSYIFSAKLWQKPKA
DAALLKTEFISKHGIVGCESCGQCRLGETLYICPETCPKGLANGPCGGSNLDRCEFEDRE
CIHSVKARLAKAVGQEKMLKQELIPTVAIETRHSSSWKNWFVPPTSPPTEH
>A0A7J4AYU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
AVNITDTPLGQPRIPGFIFAMMVKEKTGVEPIVHYKTVNMNLVNLKSVLYGCAAAGVRKF
LFMRGDNPTEGSPISDISPEELSVWARRELGVEVGLALSWPTSVEKITSKLSMKPDYVFT
QIFLSIEDAEKFHKTFEEAARRVGWSPPVYCTYLVYCEENLLTFKEVSKLMGLEMPSFKP
GIEANVDFVKELKRFFKGFMISSPGGYEHAIQLIKELRKL
>A0A7J8RR27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium davidsonii|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DALVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A427FZE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. p106|TrEMBL
MSLLKSALREKTFVCVMEFVPKPSAERFAAMEAIMARGHLCGWPMTVAIGDRVGSPLDLS
PLDALSSFSKPVPALPHFSGKDRERHDLLAQLKRMDAAGLDQLLLLTGDRLPGHQPGERP
VRYLESVAALQLARKACPHWLLGAALNPFKYREEEGGAQYFKAEKKLAAGADFLTLQLGF
DASKHQEAIQWMGRQAEPKPLLACLMSLSHGRAAMLEHVAGVTVSPSMRDMLEAEAGVSK
AYAQARSLDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEDWQARVHSQEQWTTA
WAGSWQMPGLPAVTFHPPQADWRQGQSRVSATAREKLRYHLLHGFHALLFSRNNWLSKTF
GWAVRQPLWASDSGARWLHGLERSVKRPLLGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVQQTAVLTERLIPCIEVQTRHRSSWPQWFAVQTP
ARFSPQPTLRNPPESSPQAVHRQ
>A0A7U4DLR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. (strain Y4.1MC1)|TrEMBL
MGLLQDLKERILIADGAMGTLLYSHGVDRCFEELNLSKPEDILHIHEAYIAAGAEVIQTN
TYGANYVKLARYGLEDEVPSINRAAVRLAKQAAKHKAYVLGTIGGLRSINKSAVSIDEIK
RTFREQLFVLLNEDIDGLLLETYYDLEELKTVLAIARKETDKPIIAHVSLHEVGVLQDGT
PLAEALAQLEQLGADVVGLNCRLGPYYMIRSLEEVPLPDHAFLSAYPNASLPDYRDGRLV
YETNTDYFKETALAFREQGVRLIGGCCGTTPKHIEAMANALVNRTPITEKAVKQRHVSIS
IQTNEPNAAPPLQDIVRERRSVIVELDPPKKLGIGKFLEGAKALKAANIDALTLADNSLA
TPRISNVALGTIIKEQLGVRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVER
LEKKIQCGAHYFITQPLYSEQKIEEVYEATKHLQTPIYIGIMPLVSARNADFLHHEVPGI
TLSDEIRARMAACANDPVQSAREGIAIAKSLIDAAFELFNGIYLITPFLRYEMTVELVRY
IHEKEQAAQEREVLHG
>A0A848J426|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flammeovirgaceae bacterium KN852|TrEMBL
MKVTEHFAKANKTLFSFEILPPLKGENIQKLYDHLDPLMEFNPPFIDVTYHREEFTYKKR
ENGLLERQVIRKRPGTVGICAAIKNKYNVDTVPHLICGGFTKEETENALIDLHFLGINNV
LVLRGDAMSSEARFVAEENGHNYASELLEQVSNMNAGKYLDDELTNAEHTDFCIGVAGYP
EKHFEAPNIANDLKYLKLKVDMGAQYIVTQMFFDNEKFFSFVKKCREIGINVPIIPGLKP
ITTLNHLSSLPRHFYIDLPDDLVNAVEKCKTNAEVREVGVEWAIHQSKELIDFGVPSLHF
YSMGKAEPVRRIASALF
>A0A832D3A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeropyrum sp|TrEMBL
MEILFELEPVKSRDSLRYRISSIAELVDWIDIPDSPMGTSRFSSPIVSCLVKSIAENTRV
IAHLRVIDVSRAALESIVGSLTLCGVERILFIRGDIVKGSTIIRDIEPEDAVGTVRSLKL
NIDPGLTLSLRKSIDEIMKRLRVGASFYLLLNLTSSNIDVLEYIVREAKTYNSKIYPYII
LMTEKNRDKLLRLLGRDKLCEPQEAIRLADTLKSLSLDPDGILLSSPLDFNSGLETLRVL
RRIF
>A0A7D4DXL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter pestifer|TrEMBL
MSDSTTPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLRDILQAYKNDGVRRVVALRGDMPSGMGGDAGELRHANE
LVSFIREETGDWFHIEVAAYPEMHPQATNPSADLDHFVNKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVNVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGVHFYTLNHAEAPLAVWKELAVQA
>A0A173SA62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] rectale|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNQYNVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENIPALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNNTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>A0A6S6ZN12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter pestifer|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LSNLGCDAAPHLSCVGATRQELRDILQTYKNDGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQATNPSADLDHFVTKVNAGADAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPLAVWKELAL
>A0A7S9WQY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter concisus|TrEMBL
MLKEKILNKEKGLVLYGLTPPKAEFEEAKLREISERWSWRINDIKADGLVLYEVQDESER
NDSERTFEFSGTLSPEIYYKKYLNVATPSIFYRVASGYGEDEFRAALKAQSSNLNVLVGA
TSSTQKVRLNLARAYEIASEFKELAVGGVCIAERHGKKGDEPQRMREKIAAGAKFFISQA
IFDAQLARKFLEDCAAVKISEPIFLTFSTAGNAKTLEFIKWLGVSVPSSVEERLNFSSDY
LASSCEIIKEIWCELKKFGDENGLNLSINIESVMAKRAEIEASLELTKSIRELV
>A0A2N2LKW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-9|TrEMBL
MAKITDLLRAGPTLSFEFSAPRDEDGVRRLNRTLDRLARLQPSFMSVTYGAGGSSRGPTA
EVVHHIHHDLGVTAMPHLTCVAHTREEIGVLVDHYREDGVENLLALHGDLPEGGADLRPG
QFTRAIDLVGFVRERAPFAIGVAAHPEGHPKASSMEADREHQAAKLRVADFGMTQFFFRV
EHYERFMTEMRARGVETPVIPGIMPPTNIEGIARMSAMNNTEFPAEIVARLEAAGEDVAA
RREVGVEVATRLCEGLLAAGAPGIHLYTMNFSDAPRAVVANLGLRPGLG
>A0A349AVC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKIRELMAQDKTTLSFEVFPPKKDTDFANVEKAAFGIAQLKPSYMSVTYGAGGSTKGHTI
RLAGDIQKKFSVPTIAHLTCVCATKESIEQALSQMKEAGIENILALRGDVPKDFEGNAFT
DFTHASELVKLIKENGDFCVGGACYPEIHPDSASKPADIEGLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIIPGIMPITRQVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLIANGVKHIHVYSMNKPEVAKGIQDNLSEIIRL
>A0A4Q7NGI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Motilibacter rhizosphaerae|TrEMBL
MGALLASGRPSYSFEFFPPKTDEGERQLFRAVRELEPLQPTFVSVTYGAGGSTRDRTVRI
TRRIAEDTTLLPVAHLTCVGASRAEVRSVIGQYADAGIRNVLALRGDPPAGAGTEWQPHP
EGLRYAVELVELVRSLGDFSVGVAAFPEKHPEAVDLAADAEVLVRKADAGAEYAVTQFFF
RAEDYFRLVDRLDALGCRLPVIPGLMPVTNVAQIQRMVQLSGAAFPDELAARLHAVDGDP
EGVRRVGVEIAVELGQRLLDGGAPGLHFYTLNRSTATREAYAALGLASR
>A0A5M4AR21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prolixibacter sp. SD074|TrEMBL
MKIIDIINQSDKTVFSFELLPPLKGQNADKLYRTIEELLDFDPKYINITTHRDEMEYRML
PNGLLEKRTIRKRPGTVAIAASIQNRYNVPVVPHVVCGGFTKEETENMLLDLNFMGINNV
LALRGDKLKSESIFKPEPGGHAYANELVKQIVDLRQGKYIDPDLKNNTPMDFCIGVAGYP
EKHSEATNPDVDLINLKRKVESGADYIVTQMFFDNQKYYDFIDRCRAAGINVPIIPGIKP
LSLKNQVSVLPGIFSIDIPEEFAKEVRKCKNNEDARQVGTEWAIAQAKDLVAHNVPCLHI
YTYGISDNTKQIAKAAF
>A0A2P2DHK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira ellinghausenii|TrEMBL
MNQILLEVVPRDVSVVLQEVSFVKNNFNQITGINIPDLLRFENRSWDVASVVRPIFPNVI
PHIRAIDFDLDNCEPLVKTLQQSQVPSVVVIKGDPPTDMSKQVYPTTSIKLIKKLKKEIQ
HLKVYAAVDQYRVGIKDEFDYIEMKKDAGADGFLTQPFFDMRLVDIFTEKLKGMEVYIGV
SPVVTDKSQSYWESRNRAYFPREFRPSLEWNVKFAKDVITYCSENGMNAYLMPIRINLEE
YLRRIFD
>A0A4Y9PYX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. dk485|TrEMBL
MTGKDIPGLEEARDTIPAGTKINVTFLGNEDLDMRVSAAKAVADMGFVPVPHISARRLSS
QGQLEEFLGRLQEVGATDHVFAVGGDPAEPEGPYPDSLSVIRSGVLQQYGVKEVSIAGYP
EGHPDIPSDVLWRHLEDKSAALKEQGLDAVILTQFAFDTDPVTAWIQAVRDRGIDTEIRI
GTPGPAGVKRLINFARRFGVGANAMIVKKYGFSLTNLMGTAGPDRFVTDLAALLAQNPAS
GNVRLHFYTFGGLLATSKWARDYAAARS
>A0A061A5S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces iranensis|TrEMBL
MRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSVTYGAGGSSREGTVRA
TERIATDTTLTPVAHLTAVNHSRAALRNIIGQYAGAGIRNMLALRGDPPGDPMGEWVQHP
DGLNYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFIDKCRAGADFAITQMFF
YPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIDYATKLCARLMAEEIPGLHFITLNHSTATLEIYENLGLHQRS
>A0A2J0LSE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG12_big_fil_rev_8_21_14_0_65_43_15|TrEMBL
MIKKITDIFKEKPRTYSFEFFSPKTDAGIARLYDTVGELVKLGPDFLSVTYGAGGSTRET
TTKIVDQLQKRFDVSVLHHLTCIGHTKDELTGIISNIKQAGVKNILALRGDPPVGVKEWK
KIPGGFEYSYQLVDMIRSLHKDYFSIGAAGFPECHMNCSSYELDTKYLKLKIDSGADFAL
TQLFFDNNDYFKYIDRLKKAGIKNRVIPGILPIVNYEKLVNFCSTCGASIPDKVRAIFEP
IKDNEKATHKTGVEFAVKQCQGLLDSGAPGLHFYTLNRIDPVREIIKNIKL
>A0A1A9B848|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sediminicola|TrEMBL
MALGLPSVLPNSQPAIGELIRDGRPTFSFEFFPPKTPAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWVPHPEGVHYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAVTQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PRALAERFERVADDPAAVHRLGVEQAGEMCARLLDEGVPGIHFITLNRSTATREVWQRLR
ADARV
>A0A7C1IIL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MQQMKINEIFNKKRFMFSMEVFPPKPEMDIRVVYDTIEGLKGLEPDFISVTYGAGGSTRA
RTVDIAATIQKNYNIPALAHLTCIGATKGSISAVLDELAAKGIKNVLALRGDMPKGENNP
LKDFSHAADLVAFIKKNWDFCVGVAGYPEKHPESVSTEEDIKRLKEKVDAGADFITTQLF
LDNNFYFDFVSRAQKAGIKVPVIPGIMTATSIKGIEKMAQMTGVNIPDRFRQATSSCAVD
NPVCEDTARYTVGQIDHLIKNNARAVHLYTMNKVEQNRRIYFESGLKEARKQP
>A0A355FNE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MRIKDLYQQKPVISLEVFPPKPEAPLDGVLDTIEALSDLRPDFISVTYGAAGGSKAHTVQ
IADTIKNKYGIEALAHLTCINSSKEEVDGILEELENSNIENIMALRGDRPADDSVLSPAQ
GDFAYASDLIVHLKTTGDFCIGAACYPEVHTEAENALADLGNLKRKVNAGVDFLITQLFL
DNRFFYAFREKLALMELKVPVSAGIMPVINKKQIERITSLCGASIPPKFRRILDRYENDP
EALK
>A0A6P1SMZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas albilineans|TrEMBL
MTAISFEFYPPKTDEQRVQLDRTAARLKSYAPEYVSCTFGAGGSTLSYTSETVRHLKQQH
GFETAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEYGDTFRLEVGAYPETHPQATDALSDLRHFKTKVEAGADAAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGRRMQAYGDDAESIREFGADVV
ATLCERLIAGGAPALHFYTLNLAKPTTSILARLAMEPAHD
>A0A7C2G400|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MNPFLERLQRGVLVADGAMGTMLYARGVPFDQPFELLNVTNRDLVVAVHVEYLRSGAELI
ETNTFGGNRFKLGAKGLADRVRELNRAGAKLAKEARDVAGVPVFIAGSVGPLGKPLKPFG
LVTPEEAYQAFREQVEALVEGGVDLLLLETFSDLEELGVAVRAARDCTDLPVVAEVTFDE
EGRTLRGHVPAEVVQSLEPLGVAAVGANCSVGPLPMVDVVAAMVQVASVPVTAMPNAGYP
ARVEGRYVYSTPPGYFAEHARRMAELGARVVGGCCGTTPEHIAAVAEAVRDLRPAPEPRV
VVTLPRKPEPPRPPEEATELNRKLGRQFVISVEVDPPKGTDPTKDLLGARLVKERGADAV
NVGDSPLGRVRMSASALCVLIQQHVGIETIIHFTTRDRNLMALQADLIGLHALGVRNVLA
LTGDPPRAGDYPTATAVYDTDSVGLVRILKRLNQGVDLAGKPIGQPTRFCVGVAFDMHPD
TLDREMRRLDQKIEAGADFIMTQPIFEPETLGQYLRRVGSPPLPMLVGVLPLQSSRHAEF
LHHEVPGIHIPDWVRERMARAGNQGREEGLRLAAELLDAIADRVHGVYLMPSFGRYEVVA
ELVARVRARLGLSAQVGAPRPS
>A0A7W0GKQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
DWYEIEVAAYPEYHPQSRSPADDLQSFVRKINAGADSAITQYFYNFDAYARFVDDVRALG
CTVPIVAGVMPIVSYTQLARFSDACGAEIPRWMRRRLESFGDDRESIREFGLDVVTHLCE
QLLAAGAPGLHFYTLNQAEASVELCRRLS
>A0A7Y0XXY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobiaceae bacterium|TrEMBL
MLVKEILNAATKPVFSFEFFPPKKDEEWDKLFETIAALSPLNPSYVSVTYGAGGSTRSRT
HSLVTRIQKETGLTVVSHLTCICSDKEETGTILQNYREHGINNVLALRGDKPAGSASMAE
SLKDFPHAIDLVRFIKTNYPDIGVGVAGFPEGHPETPNRLKEIEYLKEKVDAGADYIVTQ
LFFDNRDYFDFVERCIIAGITVPVIPGIMPITTQKGMIRMSELALGARIPASLITKVQNA
EKDTEVASIGIEWATNQVQELIDHHIRGIHFYTLNMADATLQIFNNIHQ
>A0A7Y5UMG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MNQTRGLPISIEFFPPNTPVGSEKLKAVVHELGALQPQFFSVTYGAGGSTRDKTLATVRE
IAAAGFEAAPHLSCVGSTRAGLAEILATYRTQGIRRIVALRGDLPSGTAVAGEFRHAAEL
VRYIREVQGPDWHIEVAAYPEYHPEQRYARRDLQHFADKMAAGANSAITQFFFNPDAYFH
FVDEVRRLGVTAPIVPGIMPFHNFARVAQFAARDGIEVPRWVMLKMEGYMDDTASIRAFG
LDVLTRLCERLIAGGVPGLHFYALNQSALVLEIARRLGLASAAG
>A0A6N8BAG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MKTESKLEKVLNSGKFAVTAEIGPPKHASGDGMKHHAEMLVDYVDAANITDSQTAIVRIS
SIAGGVHIKEKGVEPIVQMTCRDRNRIAMQADILGAYSLGMRNLLCLSGDHQKFGNHPTS
KNVYDVDSMQLIHLVRRMRDEKLFFSGEEIKENEPRFFVGAVANPFADPFEFRVDRLEKK
VEAGAEFIQTQCIFDMERFERFMEMVRERGIDERVHILAGITPMKSWRAAKYIGNNVSGM
IVPDELVERLKNAEDPKREGIEMAIEQINYIKENVKGVHGFHVMAIAWEEVVPEIVERCG
LYPRPNVD
>A0A547PCE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter insulae|TrEMBL
MTPTLDQLHEARTAIDTPLFSGLPGDVDVSFEFFPPKTQKMEDQLWDAVQQLKPLAPSFV
SVTYGAGGSTRERTHATVARIIAEAKMPAAAHLTCVGASKAEIREVAEQYWEAGVRHIVA
LRGDAGEPGAPFTPHPEGFASAAELVAGLKEIADFDISVAAYPETHPDADCPQSDIDNLK
RKLDAGASRAISQFFFSADKFFAFRDRLAASGIDQPVLPGILPVTNVAQARKFAGACGAE
IPPWMDGLFEGLDAKPDARKLVAATVAAELCRRLYAGGVRDFHFYTLNRSELAYAICHML
GKRPIGETA
>A0A3C1Q7Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
RRFSDRVDAVNVADCPMANVRMSPITLAHLIQRDVGVEAIFHLTCRDRNTIGLQAELLGA
SGLGVRNILALRGDPPTRGDHPEAHGVFEVDAVGLIDLAATLNSGQTVGGGNLDEGTDFA
IGCVANPNAEDLEAEISRLEQKIAAGAHFVQTQPIFDPRAYERWAEATDGRVRIPILYGI
LPIKDAAFAVHLKENVPGMAVPDWVIDRMRAGGDGEGYRLAAELLSEIGRDIAGIHIFPM
NSSKRVIGVLDALSERGFAVAPASSLPLASAGGLRKVVSNG
>A0A522SBJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MTLPISFEFFPPKTPAGVEKLRVTRQQLYALRPEYCSVTYGAGGSTRGGTFAAVAEILAE
GMEVACHFSCIGATRANVATQLDHLRRMGVKRLVALRGDLPSGYGGGGEFRYASDLIAFI
RAETGDHFRIYAACYPEVHPQAESLRTDLAALVAKVRAGADVAVTQMFFNADAYFHFVDE
VRGLGLGIPIVPGIMPITSNSGLLRFAANCGAEIPRWLRLRLQSLGDDVDAIRALGVDVM
ARLCTHLIEGGAPALHFYTVNQAAPTLALCERLHLPAQ
>N9Z470|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] clostridioforme 90A7|TrEMBL
MKIRDILAEGKPTLSFEVFPPKTEDAYDSVEKAAAEIAKLKPSFMSVTYGAGGGTSDYTV
GIASAIKEEYGVTPLAHLTCVSSTREKVHHVLGELKERGIENVLALRGDIPQDGSTPREY
HYASELIWEIKKAGDFCIGAACYPEGHVESANKSVDIDYLKQKVEAGCDFVTTQMFFDNS
ILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTYLPSRFMSIVDRFGDNPAAM
KQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A2H1ECK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum maritimum NCIMB 2154|TrEMBL
MKVTDHIKKANGKTLFSFEIVPPVKGKNIQELYQNIDPLMEFSPPFIDVTTSREEYIYIK
KKELFDRKTTRMRPGTLGICAAIKHKYDVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMNHQKYFEATHGGHLYAKNLVDQIQNLNQGKYLHGITEADHKSDFCIGVAGYP
EKHIEAPSLNSDLKRLKEKVDAGANYVVTQMFFDNKKYFNFISAAKKAGINIPIIPGIKP
IAVKRHLQLLPQVFKIDLPETLIDAVEKCKNNKEVRQIGIEWAIHQSKELLKSNVPVLHY
YSMGKSTNIKAIAKEIF
>B3JKI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola coprocola DSM 17136|TrEMBL
MRVIDLIKSPEKTAFSFEILPPLKGTGIEKLYETIDSLREFDPKYINITTHRSEYIYREL
GNGLYERKRIRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREDTEYVLLDLQFLGITDL
LILRGDKAKHEQVFTPEPGGYAHAIELEHQINDFNQGVFVDGSPIKAPVHPFSYGVACYP
EKHEEAPNMEQDIYWLKKKVEAGAEYAVTQLFYDNRKFFEFVDRVRQEGIDIPIIPGIKP
FSKLSQLSVVPKTFKVDLPQELALEALKCQTDEEARQLGVEWCINQCRELIAHGVPSIHF
YTVGATESVRRVAKEIY
>A0A1F9ARE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_49_15|TrEMBL
MKVKTPSKLEKILASGCLAVTSECGPPRGSDPEMITRKANLIKSHVDAINITDNQTSVTR
LCSLAACIHLKLMGLEPVLQMVTRDRNRIALQSDILGAASFDIHNILCLSGDHQSFGDCP
QGQNVYDIDSMQLIQTVRYMRDEGKFLGGDNLHRSPQMFVGAAANPFADPFEIRVPRLAK
KVAAGAEFIQTQCIYNLDKFELWMKMACDRGLHEKVHILAGLTPLKSAGMARYMKNRVPG
MDVPDEVVKRIAGTPKEKQPEEGIKICIESIERLKKVEGVHGFHIMAIEWEEMVPEIVEK
GGLYPRPKVE
>A0A2T8I079|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panicum hallii|TrEMBL
MKVIEKIQQAAADGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYTNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALAILMNL
GLIEESKVSRPLPWRPPTNVFRVKEDVRPIFWANRPKSYITRTLGWDQYPQGRWGDSRNP
SYGALTDHQFARPRGRGKKLQEEWAVPLKSVEDISERFTNFCEGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLELFCAKEKLD
QLVEKIKAFPSLTYIAVNKDGESFSNVPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWTRGWGCLFPEGDSSRELLEKVQKSYYLVSLVDNDYIHGDLFAAFKEI
>A0A353QGU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MARLLNRLTQGQFVVTVEIDPPRGPDAAKTLEKVRGFADRVDAVNVADCPMANVRMSPIT
LAHLIQRDAGVEAIFHLTCRDRNTIGLQAELLGAAGLGVRNILALRGDEPTRGDHPSATG
VFEIGSSRLIKLASTLNAGSTIGGSGLDCGTDFTIGCVANPNAEDLEAEVDCLEAKIAAG
AHFAQTQPVFDLRILEHWLMKAAGRVRIPILYGVMPLRNYEFAVHLNNDVPGITVPEWAV
ERMRVRGPQAGMEMVREFISSASAASEISGIHIFPMNNAARILKVVDIIDELGLRCQRKA
KPIRIGTRD
>C7DB10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobium sp. R2A62|TrEMBL
MPDPTVSFEFFPPSTLEGSFRLWDSIQTLGPLNPDFVSVTYGADGTTRERTHDAVATIHK
TTGLSVAAHLTCVNASREETMAIADNYAAAGVTQIVALRGDATKGETTFQPHADGFQSSC
DLISALAETEKFDIRVGAYPETHPEARSTIADIDYLKAKIDAGATSAITQFFFEAETFLR
FRDACAAAGITAPILPGILPVENWTGVQKFARSCGASIPAVLAQAFDNANRDSCHDLLAV
AHASGLCSELLDEGVDHLHFYTLNKPELTRDVCGALGLAPQTLLKNVA
>A0A350NM85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MARLLNRLTQGQFVVTVEIDPPRGPDAAKTLEKVRGFADRVDAVNVADCPMANVRMSPIT
LAHLIQRDAGVEAIFHLTCRDRNTIGLQAELLGAAGLGVRNILALRGDEPTRGDHPSATG
VFEIGSSRLIKLASTLNAGSTIGGSGLDCGTDFTIGCVANPNAEDLEAEVDRLEAKIAAG
AHFAQTQPVFDLRILEHWLMKVAGRVRIPILYGVMPLRNYEFAVHLNNDVPGITVPEWA
>A2SL02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1)|TrEMBL
MSDTPSLRLPVPVSFEFFPPNTEAGSEKLKTVVRELGSAAPEFFSVTYGAGGSTRDRTLS
TVRDIAALGFEAAPHLSCVGSTRVGIAEILGTYRAQNIRRLVALRGDLPSGTATAGEFRY
ANELIAFVRETQGTDLRIEVAAYPEYHPQQRYARRDLQHFANKMKAGADAAITQFFYNPD
AYFHFLDEVRALGVDAPIVPGIMPFHNYARIAQFAMRDGIEIPRWVALKMEGYMDDAASI
RAFGIEVVSRLCERLIAGGAPAIHFYTLNQSALTLEVCRRLASARA
>A0A6N8KZY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium humi|TrEMBL
MKIVDHIKNAKGKPLYSFELLPPNKGQGIQSIFRTMDELMEFKPPFIDVTYHREDYLYKQ
HANGLLERVSYRKRPGTVAICAAIMSKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDSDFIPTVGGHSYATELLEQVVDMNHGRYLHEDIESSEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVNKCRENDIHVPIIPGLK
PLTSKNQLITLPRIFHLDIPEDLSDAVEACKTNADVRQVGEEWLVQQCKELIDFGAPVLH
FYTMSNPGPTKKIVEKLV
>A0A7W6R0V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium esperanzae|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWQTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGISIPIVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIDEFHLYTMNRSPLVSAVLDNLGLSRRPAKSAGAAA
>A0A846HNL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halochromatium sp|TrEMBL
MTDLNDRTFSFELFPPKTDEGMDKLKTTVQRLNAVNPRYFSCTYGAGGSTRERTFATVDW
LREQDIDTAPHLACIGSEKDEIRDIVGHYIDKGINRLVALRGDMPSGMGRTGLGTFRYAN
ELVTFLREEYGDRFTIEVAAYPEFHPQARNAQADLENFKRKVEAGADAAITQYFYSAEAY
FWFVEECQRMQIEVPIVAGIMPISNYSQLARFSDACGAEIPRWIRKRLEGFGDDKESIRS
FGHDVVLELCQRLLDGGAPGLHFYTMNQSAPTLKLWRELGLPEAD
>A0A221MGT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Virgibacillus necropolis|TrEMBL
MDLLKTLKERILIGDGAMGTLLYSYGVDRCFEELNLTHEVQIAHVHQAYIDAGADLIQTN
TYGANYIKLARYGLEDQVKKINTAAINIAKQVASDHTFVLGTIGGIHGTQTSLGTKEEIK
RSFREQLYCLLLGNVDGLILETYYNLDELTTVLEIAREETNLPIIANVSMHEAGILENGI
HLSDALQRLEDTGADIVGINCRLGPHHMVESLKNVPLSRNSFLASYPNASLPAYHDGKLI
YENEPDYFENCARDFRNEGVRLIGGCCGTTPEHIHALARGVKGLKPLTEKKIIKRPSSIK
VKENQVRTETPLLDIVKKRHTVIVELDAPKHLDTTEYMEGVRALKEVGVDAITLADNSLA
TPRISNLAIATKIKREIGLRPLVHLTCRDRNLIGLQSHLMGLHTLDINEILAITGDPTKI
GDFPGATSVFDVTSFDLIKLIKQSNDGLSFSGKSLRQATSFHVGAAFNPNVARLDKAVER
LEKKIACGTDYFLTQPIYSPEKIIDLAVATKHIDTPIFVGIMPLTSTKNAEFLHNEVPGI
KLTESIRAKMRSASADKEQSVEQGITIAKGLIDVALENFHGIYLITPFMRYDISIRLVEY
IQKKVQSKRLGEVLSTARL
>A0A829GVU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei subsp. tolerans Lpl14|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDKFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A7W6XPD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium esperanzae|TrEMBL
MKLLVRRTGQVRRALTNYTKAILSEAKLEIRLRKCRRKGIGMVNLGLKSKLEYRDALERF
SLEVTAKDASQLSALSGDIPKGTIISVPYLPSDSEHDRIVAAKTVRQLGCEPMPHIAARR
IGTEAELSDVISNFVREAQVARLLILAGDLDPPKGAFQDTATILRSSVLEQHGIRHVAIA
GHPEGHPSQTSATLTNALLEKRQILEALNLEWSIFTQFTFSAEPVLDWIAGIRSKGITVP
IHVGIPGPASVRTLLRFAAVCGVSASTAVFRKYGLSITQLLTSAGPDVLVDDYANALVDE
AYGDVRLHFYPFGGVRKSVEWIRSYQT
>A0A537J854|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrabacteria group bacterium ANGP1|TrEMBL
MTSPRHPLLARLDGGPLLCDGAMGTLLYERGVPYDRCFDALNLTDRERVLNVHLDYLRAG
AEMIETNTFGANAVKLDAHDLGNRVRDVNWHGAKIAKEARDIIGRAIWVAGSVGPLGKPV
APFGRISAAEARDVFRAQIDALVEGGVDALVLETFTDLDELLEAVRAARASCDLPVIAQM
SFTDDGRTRYGHGPAEVVAGLEQAGVDVIGANCSVGPVPMLEVIQRMASLTRRPLSAQPN
AGFPALVDGRYLYLSSPTHLAAYARKMVEAGAVVIGGCCGTTPAHISAIGQAIADLRPAP
FRAVLPEAPGRAEPIAPPVDQPTQLAEKLGRTFVISVEVDPPKGLDATKDLDGARLLKEA
GADVIDVGDSPIGRIRMGALAMCYLIQQQVGIETIIHFTTRDRNLMGVQADLIGAHALGV
RNILALTGEPPRGDYPNVTAVFDVDSVGLVRIIRRFNEGQDLAGRSIGRPARFLIGCALD
MNPETLDREVPRLERKLEAGADFFMTQPVYEPETLDGFERRVGKLPVPVLLGILPLQSFR
HAEFLHNEVPGITIPRWVRDRMQAAGAEGREEGLRLGRELLGALLGRIDGAYFMPSFGRY
ELVATLVREVRTRVAGHAARTRG
>A0A537J9E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrabacteria group bacterium ANGP1|TrEMBL
MTPPQHPFLARLARGPLLCDGAMGTLLYERGVPYDRCFDALNLTDRERVLNVHLDYLRAG
AEMIETNTFGANAMKLEAHGLADRVRDINWHGAKVAKEARDIIGQAVWIAGSIGPIGKPL
VPYGRVTREEAGAAFRAQIDALVEGGADVLILETFTDLEELLEAVRAARATSDLPVIAQM
SFSEDGRTRYGHGPAEVASALEAAGVDVIGANCSVGPVPMLDLVQQMAAHTRTPLSAQPN
AGFPTLLEGRYLYMSSPEHMALYARKMVEAGAVIIGGCCGTTPVHIAAIGQAIQALRPAA
VRTPAAVPKGRAEPVAPSVDQPTQLAQKLGRAFVISVEVDPPKGLDATKDLEGARLLREA
GADVIDVGDSPIGRVRMGALAMCVLIQQEVGIETIIHFTTRDRNLMGVQA
>A0A6G6X8E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altererythrobacter sp. BO-6|TrEMBL
MSPTLDQMQEARTALDSPLFKGLPGDIEVSFEFFPPKTEKMGETLWQSVETLKPLDPRFV
SVTYGAGGSTRERTHQQVVRIQNEAGIPAAAHLTCVAATKEEVNEVARRYWEEGIRHIVA
LRGDPPDGSGKFTPHPGGYANAVELIAGLKEVADFEISVAAYPEVHPDSPDAQADLDNLK
AKFDAGATRAITQFFFNTRCFFEFRDKAAAAGINGEIVPGVMPVLSFAAVQRMSGLCGTA
IPAWMEGLFEGLDERPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GMRPKAGL
>A0A3S5YDZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. arizonae serovar 18:z4,z23:- str. CVM N26626|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A318T1T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium leguminum|TrEMBL
MSVFGLSRRPDIGQTTRVSFEFFPPKTEEMETRLWETVTRLAPLKPEFVSVTYGAGGSTR
ERTARTVARILKETDVTPAAHLTCVDATKEEVDAVVREFASLGIKRFVALRGDPAAGIGA
QYRPTPGGYHNGAELVAGLRAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPILPGILPIHNFKQVTNFCARSGTHVPAWLTERFD
GLENDPQTHMLVAAAVAAEQVLDLVERGVQDFHFYTMNRADLAFAICHMIGIRPQKQGTD
AVGASLAGAAA
>B1ZGE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)|TrEMBL
MPNSSRHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVNATREEIDAVVQSYWDAGVRHIVALRGDPAEGVG
HTYRPHPGGYAQTCDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFDNEIYLRYLEKVRAAGIDIPIIPGILPVQNFKQAASFARRTGASVPYWLAARF
EGLDNDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
PAAKPEAKAA
>A0A2M9XAL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira hartskeerlii|TrEMBL
MKKILEIYKTAKTPVYSFEFFPPKTPEGEVKLFEAVEELSKVDPGYITVTYGAGGSTRDK
TIRITSELAKKFSLPAAAHFTCVGGNKDEIRVILKQIRESGIENLMALRGDPPKGEEAFK
KVEGGFSHASELISFIKAEGFDFCMGAACYPEKHPEAASLESDVDNLKRKVDSGASYLVS
QLFFKNSNFESFLNLIRKKGINVPVIPGIMPITSFAQIERFKAMAACEFPEKLVSDLEEV
KDQPQEFYKRSTNFSVSQCRELVKMGAPGIHLYTLNQSPASLDIVRELKKLKE
>A0A380PWB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia frederiksenii|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRAIATDYWNSGIRHIVALRGD
LPPNSGKPEMYASDLVTLLRDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMSTIFE
GLDDDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A3R6VSC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. AF18-52|TrEMBL
MKVIDLINGSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFNPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQNTDLYHEHATGLQQQVNNFNKGIAIDGSTFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVDRCRAEGITVPIIPGIKPV
VFKTQLTVLPKIFRSDIPEPFAAELRKCKNDDEVKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMATDSVYKVAKEVY
>A0A4P6HMD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solidesulfovibrio carbinolicus|TrEMBL
MRIRELMEARRPFVSLEFFPPKEREAWDGFFGVVEKLIPVRPLFVSVTYGAGGSTHAHTL
EIVSRLKTAYGLEPMAHLTCVGASKDKIRGFLDALAEAGVDNVLALRGDPPKGQETFVPD
SEDFQHASDLVAFIRAEYPNLCLGVAGYPECHPEATSPEKDLEHLRHKLALGGSFAVTQL
FFDNDRYFDFVARARAAGIDAPMVPGVLPVLSLASIKRFAALCGASLPPAYMAELEAADA
AGGNAAVAEVGIAYARKQAQDLLRRGAPGVHLYTLNKAEAVLSIVSGLEY
>A0A2M9QW47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas lactitubi|TrEMBL
MSGGTGRLGQPSNGTADRAQRAQAFVSAVSLEVSAKAMPALRAEAARMARGTTISIPYLP
SEDDTARLAAARTVRELGFEPMPHLSARRIGSRAALEHFIDRAVIDAGVERCLLIAGDLS
TPAGPFADSASIIESGVLERAGIKVVAVGAHPQGHPVMTSADRWRVLERKCQRIEARGMA
PLVVTQFAFDADVVLTWLNELRARGITHPVLVGVPGPASIARLVRYAAMCGVAASTSMLS
RYGISMGRLLGRAGPDVFVDRLVDGLTEAHGQVSPHLFPFGGIAQSMEWVEHYRMRAGEL
MTQDERRSPHRPSPG
>A0A0B4EJ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leisingera sp. ANG1|TrEMBL
MTTPKISFEFFPPQNLEASFRLWDTVQVLAPMDPRFVSVTYGAGGTTRTLTRDAVSTLHK
SSGLNVAAHLTCVNASKAETLEIADQFAEAGVTEIVALRGDPPKGEGKFIPHPDGFANSV
ELIKGLKTRGNFNIKVGAYPDRHPDAADQAADVEWLKRKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDGSKLTPGILPIENWKGARNFAKRCGTIIPDWVENAFEKALRDDREELLA
TALCTELCSDLLEGGVDKLHFYTLNRPELTRDVCFALGVTPKVSLQNVA
>A0A087MFX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenimonas donghaensis DSM 18148 = HO3-R19|TrEMBL
MTAISLEFYPPKNDDQRAQLERTVRKLKPRSPEFVSVTFGAGGSTLSYTPETVRGLRAHH
GLDAVPHLSCVGGTRAELGELLDTYKAMGCTRIVALRGDLPSGMARAGEFRYAADLVAFI
RETHGDHFRIEVGCYPETHPQAECALSDLRNFKAKVAAGADSAITQYFFNADAYFRFVED
MRAGGIDIPIIPGIMPISNFSQLRRFSEACGAEIPRWMAKRMQAYGDDADSIREFAADAV
AAMCRRLVEGGAPELHFYTLNLARPTEAVLSRLG
>A0A7K6G0R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Daphoenositta chrysoptera|TrEMBL
MVNETQHPCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6N2C2S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solanum chilense|TrEMBL
MKVIEKIQESVKDDRVVFSFEFFPPKTEDGVDNLFERMERMVSHNPSFCDITWGAGGSTA
DLTLEISNRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGLATLETYENELAYLK
RKVDAGADLIVTQLFYDTDNFLKFISDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTR
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKIMASGIKTLHLYTLNMEKSALAILMNL
GLIEESKISRPLPWRRPTNVFRIKEDVRPIFWANRPKSYISRTIGWDEFPHGRWGNAKNP
SYGALSDYQFMRARSRDKKLQEEWAIALNSVEDIYERFMYYCLGKLRSCPWSELDGLQAE
TKIIDDHLGNINSKGFLTINSQPSVNGAKSDAPLVGWGGPGGYVYQKAYLEFFCSREKLN
AVIEKCTAYPFLTYMAVNKKGNWMSNVNQIDVNAVTWGVFPSKEIVQPTVVDPASFMVWK
DEAFEIWSRGWAQLYPENDPSRTLLEQVQNSYFLVSLVDNDYINGDLFAIFKDIWN
>A0A1F1ELC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. HMSC066A08|TrEMBL
MSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDRTLSTVLQL
DGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMASGELRYANE
LVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQYFFNADAYF
YFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSRSIQAF
GEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A0G4LS86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium longisporum|TrEMBL
EKWVAADGGFEYARDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGA
TFIVTQMFYDADNFVRWVGKVRERGITIPIVPGIMPIATYASFMRRAKHMNCSV
>A0A1V4SDJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4484_190.3|TrEMBL
MSEYKAESNLEKVLKAGHFAFTGECGPPQGANVEALKEKAKHLKGCVDAVNVTDNQTAVV
RMSSWAASLVLLQEGLEPNFQMVCRDRNRLAMQSDILGIYAHGIRNMLCLSGDHQKFGNH
PGSKNVFDIDSMQLINMVKLMRDEGKFLNGQDIDVSPRLFIGAASNPFGDPSEFRVYRLA
KKIAAGADFVQTQCIYNMKRFREFMKQVVDMGLHEKCAILAGVTPMKSVGMARYMAKQVP
GMDVPEELIKRLQGAGKGKVAEEGIRFAIEQIEEFKEMEGIAGVHLMAIEWEHRVPEIAE
RAGVLPRPEI
>A0A0G4MN19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium longisporum|TrEMBL
MDKITDKIAALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
AFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPPRKAE
YQDAVDEESDDGEDFVWATDLVKYIRKNHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVEKTQAGADFIMTQLFFDIDAYDHFEQVLREXPSGAFKTIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDALMARLDAVKGDDEKVKEVGVDIVSELVDQIRAVKSKRTTGPQGFHFYTL
NLEKAVSFILERTNLIPDKEQEDEEAVIDDATTPPVVPTVQINGLHPGSHHRPGRRQSSI
GSDPHNRVIVSSASNHAYETNPEGAGLPAEPINTRANTLAISEGEGVLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVTQAVRLWGHPKSSEDISTLFIKHIRGELSAIPWSEE
GLSPETNIIQEQLIELNTRGWWTVASQPAVNGVPSRDATFGWGPSHGFVFQKAFVELFLP
AADWKVLSERLTGPEVEGTVCFYACNGNGDFATSDDSGGLVRTAVPASTNAVTWGVFPGK
EIITPTIIEEVSFRAWSEEAFKIWGEWSRVYGRGHESENFLKTVKDEYWLVNIIHHDFVE
TNALWDLLRG
>A0A2H3HM20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. radicis-cucumerinum|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A0C1XH22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 150FB|TrEMBL
MRDLLASGPTYSFEFWAPKTEKGERNLWNALRRIESVPPSFVSVTYGAGGSTREGTVRAT
EQIAADTTLTPVAHLTAVGQSVADLRNMVGQYADAGIRNILAVRGDPPGDPMGEWTAHPE
GVRYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVRHFVDKCRAGADYAITQMFFD
PDGYLRLRDRLEAAGCATPIIPEIMPVTSVKQLERLGKLSTAVFPPELKERILSAKEDPA
AVRSIGIGFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGLHEQS
>V5GSE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kalmanozyma brasiliensis (strain GHG001)|TrEMBL
MSNGIDSSLPPKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADL
GPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGC
RNILALRGDPPTGQSEWEPHAAGFSRAKELVEYIREQYGDYFAIAVAGFPEGHPEAIDGS
DKELERLKEKIDAGADFIFTQMFYDFDIFAKWVKDVRAAGITCPIIPGVMPIQTYGGFQR
ATARFGTLVPQYFHDALDPVKDDDQKVRDIGTRLVGEMCKKIVGTGLGISGLHIYTMNLE
KGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRREEKIRPIFWANRAKSYVNRTEDWDEFP
NGRWGDARSPAYGDFDAYGVKLRYSNDEAKEMWGNPTSLDDVKALFQKFCAGDVKALPWS
ETGVARETSVISEKLTKMNELGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEFF
VSPEDLDALIARIEADPQITYHAVNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVES
ISFLAWKDEAYEIGRNWAKVYEPSSPSRKYLEDMFNSYFLVNVVHNDFKSSDAIFQPFLS
ASKANAGINGSLSNLGSAVSDAAGLVTDSISSLANGHSNGHASAHATAA
>A0A1B7V7H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabaena sp. LE011-02|TrEMBL
MPDTHSFSAFNNFRKAALAGEFLITAEVAPPKGGDPVHMISMAATLKGRVHAVNITDGSR
AVMRMSSLVASVILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPQAKAVFDLEAVRLLQLIRNMNQGFDFNEKPLTDGALDLFAGAAVDPQSQSWSGLQS
RFEKKIVAGAQFFQSQLITDFEILEKFMDKIAVGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEEGMKIAAEQVQIARGLCQGVHLMAVKREDLIAPILDLAGV
EKVS
>F4XT82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena producens 3L|TrEMBL
MTNPTNNSFRTAVESGEFLITAEVAPPKGGNAAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILHQQGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFER
KLEAGAQFFQSQLICDFDRLEKFMVQIAAGTNKPILAGIFLLKSAKNAKFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLARQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSPVNDLVFK
>A0A432JAS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MEYQSLLHKKLSEGIFVFTAETTPPDASNQEVLLKKTMPLKGVADAVNVTDSPGAKVHMS
SLTAAIILAQNDIEPILQLTVRDRNRLALQGDLVGASALGVHNILCLSGDDPKVGDQPET
KPVQDINSATLVTTANMMRKDKQFPSGRIIDPPPKLFIGAAEVPSKGKPNTKKILNKIKI
GVDFFQTQYIFEKKKLIDYMKVLDDVGILEKTYFLIGLGPFASAKSAKWMNDNLFGVDVP
DEIIKRLEQAKDQKEESKKICLELIQIFREIKGVKGIHLMGHKKEELIAEIIKESKIS
>A0A5U3RYE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGGGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7C7J5H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MAVSFEFFPPKTEKTVERLWRSVDRLAPLRPRFVSVTYGAGGSTRDRTHAIVAHLRRNTD
LEPAAHLTCVGASVEEVNAVVRDYYAAGVRHIVALRGDPPEGESKFTPHPEGYDGSVELI
SGLKTIADFEISVGAYPEPHPDSRGMQSELDYLKRKLDAGATRFITQFFFDNDCFLRFLD
KVRGAGIEAPIVPGILPVTNFQQVARFSSMCGASIPDWFGSRFDGLDDDPSTRQLVAAHT
AADQCFGLLESGINEFHFYTLNRADLVFAICHMLGVRAGPTAATGAD
>A0A1U7FUL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3Y4TD89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSQMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7C4ZIU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanithermus profundus|TrEMBL
MRLIDKLGHGFVLTAEVDPPRGPDPGPTLQQALILRGYVDAVNVSDAPMANLRMNSFMLA
HLIQHHTGVEVIPHLTARDRNRLALQADLLGAWALGVRNVLVLGGDPPERGDHPEAKPVY
EFGAVGLVQTVARLNRGENLSGGSLEGTTDLTPGVAVNPGASDLGAEAEKFWAKVEAGAR
FAQSQPVFCPETAAAFLDALGGRSPVPILWGVLPLRSVKMARNVARWTRVPEALLADLER
EGRAAGMRAAQHVLRELHAAGMDGAHLYPLGKVALLKEMLSPLGTRLR
>A0A7W8NU16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. SJZ102|TrEMBL
MNKHNFSIEFFPPKTPEGAEKLRATRARLAELQPKYFSVTFGAGGSTQQGTRDTVLEITA
EGHEAAPHLSCIGSSRASLRAILDDYKTNGVKRLVALRGDLPSGYGAMGQASSEFRYANE
LVEFVRAETGDWFHIEVAAYPEMHPQAKSPQDDVQNYARKVKAGANSAITQYFYNADAYF
RFVDDAAKLGAEVPVIAGIMPITNYSQLVRFSDMCGTEIPRWVRLKLASYGDDVDSIRAF
GLDVVSQLCERLLAGGAPGLHFYSLNQAGPTQAVWQRLVK
>A0A3N1Q392|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PanSC19|TrEMBL
MNPTYSFEFFPPKTDKGEQTLWDAIRRVEALKPDFVSVTYGAGGSSRDRTIEVTKRIVTE
TTMRPVAHLTAVGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRGAWTPHPQGFTYAY
ELVELVRSLGEFRIGVAAFPEGHPRSADAKTDLAHFVAKCRAGADYAITQMFFDPEDYLR
LRDRVAAAGCDTPIIPEIMPATDVRQVRRFAELSDAAFPEDLAHRLEAAKDDPAAAYRIG
VEHATRMGLRLLDEGAPGLHYITLNKSTAALEIHRTVMSARRVAAHV
>A0A3M1LSF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MMIPTAEAGRSILRETLRSGRFCITAELTPPVSTDPAVLLAAVRPLQGAVHAVNLTDGPG
ANPRMSSIAAAALLLRSGIEPVVQMACRDRNRLGLQGDAIGAAALGIRNVLVLRGDDPAR
GSQPGAKPVFDLDTRGLLATLAAIRDEGT
>A0A2R4N158|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carboxydocella thermautotrophica|TrEMBL
MKAGSKLEQLLRRGEFVVSGEIGPPKSCDANVIKKHGEHLRNAADAFNLTDNQTAIVRMS
SIAAGKILVDMGIEPIIQMTCRDRNRIGLQSDALGAAALGIKNILCLSGDHQRFGNHPMA
KNVWDLDSIQLLQTLDGMRKGYFQCGEQMKSEPPKFFLGCAANPFADPFEFRVTRLEKKI
NAGADFVQTQCILDMERFERWMELVRERGLHERAYILAGVMPIKSAKAARYMQKNVAGMM
VSEEICQRLEKAEDVKEEAVNLVVEQIKYLRNMKGIAGVHIMAVAWEEIIPTIVERAGLL
PRPTI
>A0A447TQJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MEQTLWNSIDRLSSLKPKFVSVTYGANSGERDRTHSVIKGIKERTGL
>A0A1Q8UDC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MNU77|TrEMBL
MALGTPSTRTDHALTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A0F2LXZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporothrix schenckii 1099-18|TrEMBL
MHIRDMIVEAEKDGLPSFSFEYFPPKTAQGVQNLYERMERMHLFGPKFIDITWGAGGHVA
ELTAEMVTQAQTYFGLETCMHLTCTDMGEAAVNDALRRAYRAGCTNILALRGDPPRDKET
WEATDGNFCYARDLVRHICKTYGNHFDIGVAGYPEGTDDNKDEDMLLDHLKEKVDAGASF
IVTQMFYDVENFLRWLARVRERGITVPVLPGIMPIATYASFMRRVNHMGCKVPARWVEKL
EPVKNNDDAVREIGKSLVAQLCRDILAGGDVKHLHFYTMNLAQATRMVLDELDWLPSADR
PRPPPALPWKQSLGLGRREEAVRPIFWRNRGKSYVSRTADWDEFPNGRWGDSRSPAFGDL
GNAYGVGLPGTNAQNRAKWGEPRSIADVASIFVRYLKGELQSLPWSESPLTGEADKIQQD
LIDLNKHGLLTINSQPAVDSAPSSDPVHGWGPPNGYVYQKAYLELLVPPALYAEVIQRVQ
AHPHLTYHAVTWKGKLETNAPGDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLG
ADWSRCFEAGSPSRTLIRGMMDEWHIVTIVNNDFHQPRTIFEVLAGLQLSDMDKEVEAEP
VEAPAAAEATPVKPVKDTVDAQAAAVPA
>A0A537S8Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTEVTPSAFDGHRAVHSPRISFEFFPPKTEEMERSLWETVNRLAPLTPNFVSVTYGAGGS
TRERTHSTIARILKETRLTPAAHLTCVGAPKGEIDDVVARYHEIGVRHIVALRGDPTTGI
GTAYRAHPDGYQSSPDLIEGIKKRYPDIEISVSAYPEKHPESPTIDADIDTLKAKVDAGA
TRAITQVFFDNDLYFRYLDRVRAHGIDIPVVPGIMPMHNFKQARNFVTRAGTTVPTWLAD
KFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRASGA
RKAA
>A0A3M2E8W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MVRAVAGHSRGSVSFEFFPPSTPEATLRLWRSVERLAPLGPRFVSVTYGAGGTTRDRTLA
AIMTIRDRARLDVAGHLTCVGATREETLEVARAYRRLGARAVVALRGDPPKGTARFQPHP
GGFRNAAELVAALKADGAGEIYVAAYPEVHPEAASAEADLDNLRAKVEAGATAAITQFFF
DTERFLRFRDRAAAAGIHAPILPGILPIENFEKMCGFAARCGTHVPEQLHRAFARAETAE
DRQLLATAIACEQCDRLRAEGVGHFHFYTLNNPDLTFNICRALGFEAVPLSIAAGGAA
>A0A1C6Z4K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hafnia alvei|TrEMBL
MSFFHANQREALNQSLAELHGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGGGKPDMYACDLVSLLKEVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEVHSPI
IA
>A0A1Q3VR48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter sp. 66-26|TrEMBL
MKHTELSIEFFPPQTPEGVDKLRIVRGKLAALKPEFFSVTFGAGGSTRERTFAAVKEIAA
EGYAAAPHLSCIGTTRAGIREILADYQAAGIRRIVTLRGDLPSGMAETGEFRYANELVEF
IRAETGDRFRLEVAAYPEWHPQARTPADDLAAFARKVKAGADSAITQYFFNADSYFHFVD
AARALGVDVPIVPGIMPIASFSKLARFSDACGAELPRWMRKQFESYGDDNDAIRAFGLDI
VTELCERLLAGGAPGLHFYSMNQSALTLEICRRLGLGQTAD
>A0A537NYZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTARQPASRLEALLRARQFAITAEITPPVSCEADDLLRKALPLAGLADAVNVTDGAGARA
HLSAPIAACLLARAGIEPVLQFTCRDRNRLALEADLMGAAACSVRNVLCLTGDDPRAGDQ
PQTKPVFDVDSVALTAIARELRDKGELPSGRKVAGHAAFFLGAADVPIDPPPSWRPDKLA
AKAAAGAEFAQTQFCMDTGVVRRYSAQLAKHAETRDLFLLIGVAPLRSARSARWMRERLY
GTIIPEAFIERLERATDAAAEGERIAVELIEELAAIPGVAGVHLMAPANQDALPRVIVEA
RKRLPSR
>A0A7J3AMF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MKPVSNLQKILDSGKFAVTAEIGPPRGADPSHMIELAGKLKGSADAFNLTDNQTAIVRLS
SIASAVILMREGLEPVIQMTCRDRNRIALQSDLLGASAIGIRNVLCLTGDHHTFGNEKSA
KGVFDLDSISLLNTFRNMRDFKRQLSGEELESPPIVYLGAAENPFATPYEFRALRLKKKV
DAGAQFIQTQAIFDLDWFERWMAEVRKLGLHERVHILGGVIPSKSLGAVRYMKNKVPGMK
VPDSIVTRMKNAKDKNQEKEEGLRICVEMIERLKSIEGVHGVHIMAVMWEEMVPYIVKEA
GLLPRPSL
>A0A6G7VCG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldichromatium japonicum|TrEMBL
MSSLSNQGPIYSVELFPPKTPEGMVRLKEEVGRIVDLGPAYFSVTYGAGGSTREGTFETV
SWLQAQGLIAAPHLACIGSSRAQIREILERYQQLGIRRLVALRGDLPSGMGWGNTGEFRY
ANELVSFVRAEFGEWFLIEVAAYPEYHPQASSPARDLENFKRKVEAGANGAITQYFYNAD
AYFHFVENCQRLGIEIPIVPGIMPITNYAQLARFSDICGAEIPRWIRRRLEAYGEDLDGL
REFGHEVVLRLCERLMGGGAPGLHFYSMNQAGPVLRLWRDLDLPRPRGEAAGAA
>A0A7J2KUY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MKHYSELMRSLKSSEFTISGEIDPPKDVNPDEVKEQVKHLKDTVVAANVTDNPIGDVIMN
TLAPCVIMQDLGLEAIYQQTCRDRNRIALQSDIIGAAALGIKNVLALTGDHPKMGNHPQA
KPVFDLDSVQLTGMLRKMREGSTLAGTELENPPEFHIGVGISPGIEPLEPEIIKLEKKVE
AGAEFAQTQVIYDVKILERLKDEAFHLDLPILPGFAPLKSVGMAKFMLKYVPGIRIPEET
MKKLEESKNRVETSIEIVAELIAAARDLNFPGVHIMPVGMDAHVREMVERAGEI
>A0A2E8U5L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MKIIEILKKTRPISYEFSPPRTADGIPAVLEALDELKVYRPDFVSVTYGAGGSTRAFTGE
ITVQAKKVAGVEVMAHLTCVGQTKEEIHGVLERLDAAGVENVIALRGDPPRGETEFVPVA
GGFPHATDLLSHIKANFKFGVAAACYPEGHTESVDVDADLDYIKLKVEKGADFLVTQLFY
DNRYYFDYVERAKAAGIDVPIVPGVLPVLSSAQVRRFTTLCGSTIPSDLGKLLDKYADDD
SSARDMGVEYATAQVRELWDQGVPGVHFYVLNRSYSVSRILDNLALPGHQRED
>G3RAX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gorilla gorilla gorilla|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKVGFPQSTRPFGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFAL
WIERWGKLYEEESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNA
RETEAP
>A0A534MCH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MRSGSRLERILASGGFAVTAEIAPPASADGIEIRENASRYRGAVDACNLTDCTRARVHIS
SLAAAAIAIQEGVEPVMQMVLRDRNRIALQADLLGAAALGVRNVLCLWGDPPSAGNERDA
KGVFDMKTEDMIEMFRNLRDAGTLRGGDKVKTPPKVFIGAAADPFRGSKEESFGKLRAKV
MAGADFVQTQGVYDVDAFEEWMRLVRKEWLHEKVYILAGVIPLKSAKMARFMVEKLGAVV
PTHIMDRMENAPNPRAEGLSIAVRTIKALKKVDGVRGVHLMPVGWDGVVPRLVKDAGLAP
RPETAV
>A0A3S9WEK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium lemovicicum|TrEMBL
MAHTTSTRNAAAERELVSGFSLEMTGKDVPGLIEAKDSIPQGTKINVTFLGNEDLEMRVA
ASKAVRDMGFIPVPHISARRLSSQAQLEEFLSRLQDVDATESVFVVGGDPAVPEGPYEGA
YDVIRTGILADYGVKEVSIAGYPEGHPDISDEVLWRSLDEKAVSLREQNIGTTVLTQFSF
DTDPVMTWIDQVRARGIDSTIRIGTPGPAGIKRLLGFARRFGIGANAMIVKKYGFSLTNL
MGTAGPDRFVSDLASLVSEDPAAGKVSLHFYTFGGLLATSEWARDYLGAQS
>B0KM01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida (strain GB-1)|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFETDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0D0VMK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus gattii CA1280|TrEMBL
MKITEKLQKAEKEGRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALKEAKSHGCQNILALRGDPVAGTST
WEPTPGGFMNAVDLVRYIHKHYPGEFCVAVAGFPQGHPETSDTPEGRAQEMEWLKAKVDA
GAEFIFTQMFYDTSIFFDWVKRVREAGINVPIVPGIMPIQNWEKFEKWVQRENIIVPSHF
YEALNPVRGDDEKVRQVGTKLVADMCKTILQNKEAGIKGLHIYTLNLEKGARMLLKELGF
EGRREQIAPLPWRPSLTPSRREETIRPIFWANRTRSYLSRTADWDEFPNGRWGDSRSPAY
GDLDGYPVSIGITAPDAYNLWGHPTTSFDLHTLFARFCRGDLAKLPWSTQPPASETSLII
EQLAKMNELGYLTINSQPAVDGVRSDDKVHGWGPAGGYVYQKAYLEFFVSPDLLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWAHLYPAGSPSRKLITDTMNTSYLVNIVANDFRDGMSIFEPFLLNQTTVGKVVEGV
KGTVEGIVEGVKGVVSA
>G7DSI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970)|TrEMBL
MVHAKISDKIRAAHNEGRNWWSFEYFPPRTEQGLINLYDRIGRMAALGPIFIDITWGAGG
TTSDATTQFVKTAHEQFGLETNMHLTCTNMEVGMVERALKEAYDSGCRNILALRGDPPRG
QEEWKATEGGFNHAIDLIKYIRKNYDDYFDIAVAGFPEGHPQASSRAEEIEHLKAKIDAG
ASIIITQMFYDIDTFINWAHDVRKAGINALIVPGIMPIQGWQSFQKCISFSKTIVPQHFF
DVLEPIKDDDAAVREAGTKLVADMCRQILDSPFDIHGLHFYTMNLEKATSMLLEELNFTA
SVEITNPLPWKPSLTTKRRSESIRPIFWANRAGSYRARTESWDEFPNGRWGDSRSPAFGK
FEGYGITLKPERGECLSMWGSPTTFADIASLFARFCRGEIAALPWSDEPAAKETSIIGEA
LAKMNLAGYLTINSQPVVDGAPSSDPVHGWGPRGGYVYQKAYLEFFCKAEQATALFKRFE
AEPSITYYAVNKQGDLRTNTATEGPNAVTWGVFPCREIAQPTIVEQTSFMAWKDEAFELG
SQWAKLYPAESASRELISSFFDNCYLINIVDNDYRNSSKTAIFRFFDEQKLSTSRTASTN
GTATNGVH
>A0A2K9N8N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niveispirillum cyanobacteriorum|TrEMBL
MSLSALMDAAANPAPLITAPGDLTVSFEFFPPKTEKMHENLWTAIRRLAPLNPAFMSVTY
GAGGSTRERTHATVTGIQAETGIPAAAHLTCVAATREEIDEIARNYWDAGIRHIVALRGD
PPPRADGTGGLGGRGYEPHPGGYAYAADLVAGLKRIGDFDISVACFPEVHPEAPSAQIDL
DNLKRKVDAGANRAISQFFFDVDAFLRFRDKAAASGIHVPMVPGILPILNFTKAAEMGEK
CNTAIPAWMRDLFDGLDEAPETRHLVAATVAIEQCRYLEKHGVKQFHFYTMNRADLTVAI
CHMLGVRAAKG
>A0A1R1IC38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azonexus hydrophilus|TrEMBL
MKPEISIEFFPPQTPEGIEKLRSTRAELAKLNPQFFSVTYGAGGSTRERTFSVVKEIAAE
GFDAAPHLSCIGSSRDSIREILGEYKAAGIRRTVALRGDLPSGMAETGEFRYANELVEFI
RAETGDWFSIEVAAYPEWHPQARSPKDDLDAFVRKVKAGANSAITQYFYNADAYFHFVDE
ARALGVDVPIVPGIMPIVGFTKLARFSDACGADIPRWMRKKFESYGDDTESIRAFGLDLV
TELCERLLKGGAPGLHFYSMNQSALTTEICKRLG
>A0A428HHL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus cristatus|TrEMBL
MVNRQTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLAE
FISNDLEIPTIAHLPAVYLTKEMVSNILQALDRVGVNQILALRGDIFPDVAPKDDFRYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRT
AGLAYAVDQIVDLVTHDVAGIHLYTMNNAATAYHIYKATHALFNHTPSIQSF
>A0A1A0UHS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. 852014-52144_SCH5372336|TrEMBL
MTSPPVLGCPKRMEFGPCGGVRPDGQCEMRAGPCTFADVVPWSGPRHEPRPVNPPLVLTD
FSNAAFDAQDVAATAGLLAPSCDAVLVGEHQNKPDFPPTLMGSLLLDAGVAPWITLSCRD
RNRVVLEQELRGLLSIGVDTALCVTGDGRGYDVRPDVTQTFDLDGPRLVELAASIGMVAA
VPETPTAPPVHGRPARLVEKQRAGASLAVLNHVPFPAMIADFMQSARAAGLSIPVIAAVA
VFTDSVSAAVLQGLPGLELDPSVTEYVLGAADPVAAGIEAAVAEAEALLSIDGVEGVNVS
GLASASGARVGAEIKAEVGRRIQEVAA
>A0A552ALF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa Ma_OC_H_19870700_S124|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A1Y4CN69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olsenella sp. An285|TrEMBL
MRIADKLAGHQTFSFEIFPPKGDMPLETAYAVASEMAADRPDWISVTYSAGGSGNSANTV
PIAGQIEHDLGVTALAHLTCLGSAREDVDAYVAELASAGVENVLALRGDRAPGREAKDFA
HASDLIAYLRSSGADLCIGAACYPEGHVESPSEEESFRSLYLKQEAGADYLVSQLFFDNE
DFYRFREKCLRHRVRLPIVAGIMPFTSVKQIQRMAFTCGASIPAKVVKCLVLAGDDPADQ
ARAGVEYACEQLCDLAANGVDGLHVYSMNKPSVAHAAHEALLACGYLEA
>A0A6A6JRI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Westerdykella ornata|TrEMBL
MHISQKLAQAQKDGKTTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFVDITWGAGGRLS
QLTCEMVKVAQTVYGLETCMHLTCTDMEKSKLDDALREAYQAGCTNILALRGDPPREKEK
WEATAGGFRYARDLVKYIREKYGNHFDIGVAGYSEGCEDNDNVDQLIDHLKEKVDAGATF
IVTQMFYDTDIFLDWVRKVRAKGITIPIIPGIMPIHTYAAFMRRANWTKCHIPPKWLEAL
EPIKNDDVEVREVGKVLVADMCRRLIAGGITHLHFYTMNLAQATRMVLEELDLLPDVESP
LERPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNIKLWGSPTSVKDISDVFVRYMSGKLESLPWSEQPITKEAESIQQDLID
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVLISPELIAEVITRIERDP
DLTYYAVNKNGELKTNSPAGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFFRLGQDWA
NCHSSVSPSRYVIEDLMDTWYLVNIVHNDFHVTHGIFHLFDGLQVPNMDKPLHSTGTVNG
QANGESKEEVNGANTEEKSKTQAAAEALKSAASALSNGLNGVTVSAN
>A0A6N3B2I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella dispar|TrEMBL
MTLREKHQQGKFTITVELDPPKSSSAQKVFDQASRLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNEGIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNGA
HFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A160MB26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus oceanisediminis 2691|TrEMBL
MSFLNKLKNEIIIADGAMGTLLYSYGTDSCFEELNLSQSEQIQHIHEAYIGAGAELIQTN
TYAANYLKLQRYGLEDSVKEINSAAARIAKKAAKERAYVAGTIGGIRGFKPNMITLEEIK
RSFREQLYCLLLENVDGILLETYYDLEELETVLAIARKETDLPIIAQVSLQEAGVLQNQT
SIADALAKLEGIGADVLGINCRLGPHHMLKTLESVPLPKHAYLSAYPNASIPAYTDGKFH
YEGDAEYFRQSAIEFRNQGVRLLGGCCGTTPDHIKAFSDVLKGLPPIEEKETKAINKVMV
SEKPSSSRELPPLQDIVRERPSVIVELDPPRKLDTSRFFEGAKALKEAGIDSITLADNSL
ASPRVCNSALGYLVKQQTGLRPLVHVTCRDRNIIGLQSHLMGLHALGLNDILAVTGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSFSGKDLGQKAAFSVAGAFNPNVRSLEKAVG
RLEKKIEHGADYFISQPVFSEEKLLEVHEAVKDLKAPVYIGLMPLTGSRNAEFLHNEVPG
IKISDSIRNRMASLKDDPAQAGAEGIAIAKSLIDAAAELFNGIYLITPFMRYEMTVELSN
YARETTERLSRRKQHA
>A0A366MMQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp. CECT 9188|TrEMBL
MFETLISKLQDDKYLTLETTPQHEPSMNSIIDKIKKFKIDTRVDGFTCTDNPLAKLKYNS
LFAALKIQNEFKKPVIATMTMRDKNKIALQSDLLGANDFDIRAILALTGDPAKMSDQPNT
KGVFEANSLMLLKMIKSFNYGMDFSGRPFKIEPKHIFPFAVVNAYAKNFGSLEKKMHLKI
QNGAVGVITQPVFDIENVKKLLESFEVAKENVEGDKKKAQLILGLFPITKLRTALFLSAQ
VPGIHVPQFWIDELEKAHSISEDEEYKVGMKLSKNLFDEINKIHPKIHLMTANNKFEVAS
EIIG
>A0A6M8N3X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter cloacae|TrEMBL
MFETLIQKLQEDKYLTLETTPQHEPSMHNIIERIKKFKLHEKVDGFSCTDNPLAKLKYNA
LFASLKLQQEFNKPVIATMSMRDRNKIALQSDLMGANDFDVRAILALTGDPAKMSDQPHA
KGVFEANSLMLLKIIKSFNYGMDFAGRPFKIEPKQIFPFAVVNSYAKNFSTLERKMNQKI
QNGAVGIISQPVFDIENAKKLLESFNIARQDVEGDKQKAQLIFGLFPVTKLRTALFLSAQ
VPGIHVPQFWIDALENAHNISEEEEYKVGMQLSSDLFKEINRLHPKVHLMTANRFDIANE
IIS
>A0A8E6NM85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Paratyphi B str. CFSAN000542|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1X3DHP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria dumasiana|TrEMBL
MSLHSKPRKKLSFEFFPTRTPEGRAKQVITRKQLSQFDPEFFSCTSGAGGSTKEGTMQAI
QDILSEGIAAAPHLPCVGMQPQEIIDLLNEYKALGVRHIVALRGDIPSGMGAGSDGLRYA
NELVSLIKTEFNNDFHIEVAAYPEYHPQSRSAEDDINNFVRKVKAGADSAITQYFYNADA
YFRFVDDVRGRGVDIPIIPGIMPIASFSKLSRFSDTCGAEIPRWLRLKLQSYADDTASIK
ALALDVVTEMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>C0AUB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus penneri ATCC 35198|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTEEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASREELQHIAQDYWQSGIRHIVALRGD
LPDNTQKPDMYATDLVHLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFADLTNVKKFRDGCIKCL
MG
>A0A0D2Q6R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypholoma sublateritium (strain FD-334 SS-4)|TrEMBL
MSRISRLSQLEPLAISVTWGAGGSTKDRSLELAGLTQSNGLNTILHLTCTNMEMGLIDEV
LKAVKAQGIQNILALRGDAPRGEEEWIASDPRFTRATDLISYIRSVPEYSSWFCVGVAGY
PDGYADNLIDEDVEIDRLKSKVDAGANFIITQLFYDADHFLRWYQKVRAKGITVPVIPGI
MPIQTYSSFTRITKLCGARIPEALADKLASISHDDQEVKDFGVKLAVEIITKLISQGGIQ
GFHFCTLNLEKSVQRVLENLRWAGVSSLTQNKLITDPIGNISQPSLEADQEYTISPSGAT
NSATLSLSTISMTEGEGGRGELNNAASWDDFPNGRFGDFKSPAFGNQDPWGGSGLSRNEA
LLQWGSPKKIEDLTQIFLDHLHAKISHTPFSQTPLSPESLMILPYLESLTKRGWWTVGSQ
PAVNGMISTDPVVGWGPRSGYVFQKCFVEFFCETQDLENFEEKVLSRGNNWVHYFACNYK
GECRSNVPANGRNAVTWGVFAGKEIVQSTIIERESFLSWKDEAFSIWSEWSTFYRPGSVE
RQLLENVRDDRWLVNVVHHDYKNPGALWTFLLE
>A0A3L9GEF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
ANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1W1ZNR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fulvimarina manganoxydans|TrEMBL
MNQPTNPAAPIRVSFEFFPPKTEKMEETLWASIQRLAPLSPSFVSVTYGAGGSTRERTHQ
TIKRLLTETDLIPAAHLTCVDASREDIDEVIREYRATGVKHFVALRGDSQAGVGKAWEGR
EDGYRNAAELTKGLKAIDDFEISVAAYPEKHPESPDFSTDIDFLKRKVDNGATRAITQFF
FDNDIFERYVERVRRAGIYIPIVPGIAPIHDFTKIARFAGACGTSIPAWLADRFEGLESD
PVTHSHVAAAVCSDQVLDLNKRGFSDFHFYTMNRADLVYSICHILGLRPKAKDEAVARSE
AA
>A0A167Y7Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ascosphaera apis ARSEF 7405|TrEMBL
MHISEKLQAAQVDHPGRPTISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGR
LSDLTSEMVKVAQSVFGLETCMHLTCTDMPRDKIDKALRDAHDAGCTNILALRGDPPRDK
DHWEAVKGGFCYAKDLVEYIKQQYGDYFDIGVAGYSEGCDEQESPEELMKHLKAKVDAGG
TFIITQMFYDADIFLDWVQKCRAAGINVPIIPGIMPISTYAAFMRRSTWTNCRIPPDWLE
KLEPVKNDDAAVRAIGKTLVADMCRKLVAGGITHLHFYTMNLAEATKMILKELNLLPTEQ
SPIHKPLPWRQSLAPGRKGEDVRPIFWRNRHKSYVARTQTWDEFPNGRWTDSRSPAYGEL
DMYGIGLRGSNDQIKKWWGEPKTLRDISNIIVQYVEGKIDRLPWSDTAITQEADAIRGDL
VALNKRGFLSINSQPAVNGVKSSHPVYGWGPANGYVYQKAYLELLVPPTLINEILARIKT
NADLTYYSVNKAGELSTNAVDSPNAVTWGIFAGKEIIQPTVVETVSFLAWKDEAYRLGDD
WATCFEAGSPSRKLIQSIMDSWFLVNIVNNDFHRNRDIFELFDGLTVDSLNYELAETNSE
VN
>A0A316AAZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Quadrisphaera granulorum|TrEMBL
MTVGVPPASLLDDLSLEMTGKDVEKLDEARSALPAGTRINVTYLANEDLPMRVAASKAVK
DWGFVPVPHVSARRLASQAQLEEFLTALEGVGATEEVFVVGGDPATPEGPYEDSLAVIRS
GLLQRHGVQRVSVSGYPEGHPDIGDPVLWQALEGKHAALREQGLPGTVITQFGFDADAVL
AYLAAVRRRGVDLPVRVGVPGPAGIKRLLGYAKRFGVGTSAGIAKKYGLSLTNLLGTAGP
DRFLGALAAQLDPAVHGEVKLHLYTFGGLRATAEWAQQFRATHA
>A0A401GI78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sparassis crispa|TrEMBL
MKLTKKIAEHKVNRPFYTLEFFPPKTEQGFENLLARISRLVSLDPLAISVTWGAGGTTKE
RSLDLAGVTQADHGVDTILHLTCTNMQQGMVDDALRDAKQRGIENILALRGDPPRGEEYW
IPTDRRFTHGADLVSYIKSSPEFSSGFCVGVAAYPDGHTDGDIDNDGELEFLKAKVDAGA
DFIVTQLFYDVDNFLRWVKKVRAKGIRVPIIPGIMPMQTYASFLRMTKLCGTRIPTSLMA
DLEPIRHDDQQVKDYGVKLAIGMIQKLTEDGDIRGVHFCTLNLERSVYRVLEGLGWTGTS
PKITNKLITDMPTAENPELIVTAHSATDSAANSLTTGVPLEVEAGKGELNNASAWDDFPN
GRFGDYKSPAYGETDLWGSSTMSRKQALAQWGHPKSLEDLTDIFVRHLHSEIATTPFSPS
PLNPESLMILTQLEKLTRMGWWTVGSQPAIDGASSADSVVGWGPRGGYVYQKSFVEFFVE
KTDLEKIKSKVETEGGGWVNYFAGNVQGECWTNMPDDGRNAVTWGVFPGQEVAQSTIIEK
ESFLSWKDEAFSIWVEWASFYPPDSAERKLLDSILDQRWLLSIVHHDYTNPDALWTFLFK
DSPDT
>A0A1V2GB78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
>A0A1X7BUX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius aestuarii|TrEMBL
MTVPNISFEFFPPKSLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRELTRDAVDTLHK
SSGLNVAAHLTCVDASREETLAIARDFATAGVSEIVALRGDPPKGSGAFEPHPDGFSDSC
ELISALAETGKFSIRVGAYPEKHPEASDQAADIEWLKRKIDAGASEAITQFFFEADTFFR
FRDACEKAGIDAPIIPGILPIENWTNARRFSLACGANVPHWMDDLFEVAIRDDRHDLLAT
ALATELCSKLLDGGVEDLHFYTLNRPELTRDICHALGVTPQIALRDVA
>A0A091U360|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phoenicopterus ruber ruber|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FVKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A3M8SBU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSTERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSRQATPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPMWATRLGAQVLHKVEHAVKHPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTALLTERLIPCIELETRHRSSWPQWFQAQTP
RQLSPQPAPRTQPES
>A0A1E1VKS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. NAIST15-1|TrEMBL
MKNFREALHEQIIIGDGAMGTYLYQLGYPVGISYEILNVTDPEVIRNIHKQYVDAGAGLL
ETNTFTANREKLYRHGKEHLVKDINRAAVRLAREAAGNQAYVIGALGSIRAGKRENVHTN
QVIRDYHEQMSAMLEEGVDGIMFETFYDLEEMRLALQVVRELDQDVPVICQFAVEESRRT
KDGKSLLEAFRVLRDDGADVVGLNCHMGPNGVLRALEGVQGRIDLPLSAFPNAGLPDYVD
GRYNFVASAEYMAQSAVKFVQMGARIVGGCCGTTPEHVAAIVEALRDVEVPELPVQPVES
IIIEEESESMLWHDGAACYDGCDHGHDAEESIVDMVRSRHTVIVELDPPRDLDVSKFMKG
AQVLKEAGVDALTLADNSLAVTRMSNLALGYMALDKVGIRPLVHIACRDRNLIGTQSHMM
GLHALGIDHVLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNSGLAFSGKPLKQKAK
FVVGGAFNPNVKHLDKAIARLERKIEAGADYIMTQPVYDKELIVRIAEGTKHLNVPVFIG
IMPLASGRNAEYLHNEVPGIELSDEVRSRMSGLEGEAGRKEGVAIAKELLDVALTHFKGI
YFMTPFMFYEMTAELTQYVWEKAERQADPLYRLT
>A0A897IF54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. SB1-57|TrEMBL
MSQFLNKLQNNVLVADGAIGTIFYSEGLDTCPEAYNLTHPEKVERIHRSYIDAGADVIQT
NTYGANFEKLKAFGLEHKVKEIHKAAVQIAKKAANEDTFILGTVGGFRGVKQDDLSLSTI
QYHTEHQIDTLVDEGVDALLFETYYDLEELKGIVVSTKRKHHIPIIAQLTASNTNYLVDG
TPINDALKQLVEYGADIVGLNCHHGPHHMQRSFSHIELPDKAFLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIRYIKTSVKNLRPVVHKNVIPINKKV
NRTKDLNSKQSLTSKVKQGPTVIVELDTPKHLDTDQFFNNIGKLDDADIDAVTLADNSLA
TVRVSNIAAASIIKQRFNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEATKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEEVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITTHKEAIL
>A0A2M8ND42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phototrophicales bacterium|TrEMBL
MRSWECKMAKLPLRDRLKQATPLLADGAMGTLLHQRGAAINACFDALNLTSPEIVKQIHL
DYIHAGSRLIETNTFGANRYKLEEYGLSGKVVEINQTAVQIAKDAIASSGVNEDIYIAGS
VGPIRVGMRPYGRLNKSDVRTAYVEQIRALIHAGVDCILLETFTDHQEIFIALDVIKAIR
LNDDLDIPVIAQMTFSDDNRTPLGYTPARVAHELQRAGADVIGVNCGIGPNQVATVLQAM
HQTLPGLRFSAMPNAGFPQTSGGRVMYPASADYFGDYALTFKAIGASIIGGCCGTTPQHI
AAMRAALNDASRQVPNIQIIETNGDDVEAVPDHPTMLAERLADGKFTITVEIAPPRSFDV
EKLVRSAKMLRDAGADILDVADTPAARMRMSPWAVAHVIHSQVGVETVLHFPTRGRNLLR
IQGDLLAAHALDLRNLFVTMGDPTKIGDYPDANDQYDIVPSKLIELIKHKMNYGEDMGGN
SIGRPTAFTVGCALNMFANDLDKEIKVLNNKLAAGADFALGQAVFEPHRIETFIRRYEEI
NARPFELPVLMGIMPLFSLRHALFLHHEVPGISIPDHIMKRMEDAGDDAPAEGVRIAQEL
LRAVRGMVAGAYIIPAFGKYELAAEVLDAVAVPG
>J0HB24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii WSM597|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGVSIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGINEFHLYTMNRAPLVSAVLDNLGFSRRAAKSAGAAA
>A0A6P2C8I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trebonia kvetii|TrEMBL
MPVAQLLSGERVLVCDGAMGTMLHAAGAALDRSLPELNLSDPSLVATIHDSYLSAGADII
QANTFGANRLWLADHGFPDKVAEINRAGVRLAREAADRSGRQVLVAASVSPAVTAPQRRR
VGAAERMEVLREQILALIADNAADLIILETFGYLDELVEAVSVAAAVTSLPLIAQATFAD
DAHTLGGETPREVASVLSALPVAMIGTNCTVGPQRMLVVAEDLVRYSAVPVSAQPNAGQP
RRTGPRSFEFAIDGGYFSRYLTRFADAGVTLVGGCCGTTPTHIRAAAEALRTQPAAQPRP
QVAPRGVAARIAEPMAGGPASGSLADHLASGRFVVSAAITPPAAGWAGDAERAAAEFADR
GIGLVFVQPRENARTHMDSLNMALALQQRVGVETIPTITTWDKSIMSLQADLLGAHALGV
RSVVSTTGSPPVFGDYPAVDGTWEVDSVGLTALLAGLNAGRDSNGLALTARTSFCIGARV
NPTARDHDAELARVRAKLRAGAQFLVCRPVYELDALIRLVEALDGTGVPLLLSVTPLASF
EDADYLAHEVPGVAIPSATLDVMERAGRSGGRAAGIDLAASLLAKARPLVSGVILTAPGD
DPAALAPLIDALG
>A0A316KWE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda koreensis|TrEMBL
MKVTDHIEKANGETLFSFEIIPPVKGKSIQELYDNIDPLMEFNPPFIDVTTSREEFVYID
RDGLLDKKLTRMRPGTLGICASITHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMREQKYFEATKGGHPYASSLVKQIQELNRGNYLHEVIETDNCSDFCIGVAGYP
EKHMESPSLKSDLKRLKDKVDLGADYVVTQMFFDNQKYFEFVDEARKMGITVPIIPGIKP
IAVKRHLQLLPQVFRVDIPQDLVDAVEICKTNKEVRQVGVEWCIQQSKELKEAGAPVLHY
YSMGKSDNIRAIANEVF
>A0A381LLN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas euroxanthea|TrEMBL
MTPLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWISKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A0S4XPU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp. enrichment culture clone C5|TrEMBL
MFDTFCTSLCSSKPFITIEITPPHGGSIDKIIENIASLGLDKKVTGFTTTDNPLAKLKMD
SILAAIKVQQKFNKPVIATMSMRDKNKLSLQSTLLGANDFDIRCILALTGDPAKLSDQPE
VKGVLERDSTLLLSIIYKLNKGLDYSNKVLNPAPKPIYPFAVSNSHAKDTKYLLKKMIKK
LDYGARAIITQPVFGIENAKMLLRIFEEAKEISIRDTAKEAELILGQFPLVATKTANFIN
EHVPGIDVPKEIIDEMNLASMDGKEKEHNVGFAISKRIYDEIIALHPKVHLMTHNRFDLC
SELIS
>A0A2T0LZK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella shujinwangii|TrEMBL
MTSVVERLTGRAPAFSVEFFPPRDTADEAVLWRSIRELEPYDPAYLSITYGAGGSSRDGT
IRNIARVATETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGEWV
PHPEGLRYAEELVELVRSLGDFCVGVSAFPYGHPRSPDLDTDTAYLVRKFRAGADFGIAQ
LFFEAEDFLRLRDRVAAAGCDALLLPGIMPLTTPRTLHKTIELSGAEAPRWLLDRLEPLA
HDPRAFRAEGLDVVTELAARLLAEGVPDLHFYTFNRSKATRELVRRLGLSPARAFTARET
GAPVEAARG
>A0A2Z4RL10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVDRVRALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQNIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQADASLAVWNNLKLPR
>A0A5C3MMK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crucibulum laeve|TrEMBL
MKLTQKIQSRNKLRPFYTFEFFPPRTDQGFENLISRISRLATLDPLAISVTWGAGGSTKE
RSLDLAGLAQAEYGLDTVLHLTCTNMEQGLVDDVLRTANERGIQNVLALRGDPPRGEEEW
IPSDPRFAHGIDLVSYIRSSSEFSSHFCIGVAAYPDGHTESTVDEATELDYLKAKVDAGA
DFIVTQLFYDVDRFLQWLEKARQKGINVPIIPGIMPIQTHSSFARLTKLCGTRVPEDVAA
ALNPISHDDQLVKDYGVKLAIDMIQRITADGKVPGVHFCTLNLEKSVQRVLEGLQWVGGV
ATTSPNKLIAETPDDIVHPPSDVDSSTLLVTPTTATAAATTNLTTVQITEEAGRGELNNA
ATWDDFPNGRFGDFKSPAFGNQDPWGGSGISRTEVLAQWGSPKTLENLTKIFVDHLHSRI
STTPFSPGPLSPESLMILPHLEKLTKKGWWTVGSQPAVDGASSSDPVVGWGPRSGYVFQK
GFVEFFCPKEDLNAIERRVEEKGNGWVHWFAGSDKGECRSNVPKDGRNAVTWGVFPGQEI
AQTTIIEKESFLSWKEEAFSIWSEWASFYRPDSEQRKLLEDVRDQRWLVSIVHHDYKDPQ
ALWTFLFDDDDDIKVNGA
>A0A1H2J2Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula phenolica|TrEMBL
MKSGSKLERILTAGHFAFTGELGPPRGSNIQVIKEKAAPLKGMVDMVNITDNQTAMVRMS
SWAGALILAAEGLEPNYQMVCRDRNRLAMQADILGAYALGLRNILCLSGDHQKFGDHPNA
KGVFDIDSIQLVAMVKKMRDEGKFLGGDDIDEPPKMFIGAAANPFAQPFEWRIHRLAKKV
AAGADFIQTQCVYNMERIREWIKMANDMGLTEKVYILPGVTPLKTLGMAKYMKNKVPGMD
VPDEIIKRLEGVDRKKVADEGIKIACEQIAEFKEMKGVAGVHLMAIEWEHKVPEIAERAK
VLPRPEV
>A0A4S0ZYQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.156.01.1.1|TrEMBL
MNQFRFSRRPDIGEKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVIREFVDFGVTRFVALRGDPAAGVGT
IYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLGNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
AGSAAA
>A0A3A4NSP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Abyssubacteria bacterium SURF_5|TrEMBL
MKAGSNLERILTEGKFAATAELGPPKSADAEAIRKKAAILKGKVDAVNITDNQTAIVRMS
SIGAAKLTLDTGLEPIMQMVCRDRNRIAMQSDILGAAALGLKNMLCLTGDHQKAGNHPTA
KNVFDIDSLQLLQIVKNMRDNKVFQNGEEIRNTKKAPIVEPKMFLGAAENPFAHPYEFRA
IRLAKKMKAGADFIQTQCIFDIPRFKEWMKEVVDRGTHEKLFILAGVMPIKSPRVIEYMK
NNVPGMSIPDELVKRMKGASDPKEEGVNFVVELINEVRQIEGIRGVHIMAVEWEEIVPSI
VERAGLLPRP
>A0A0M3CRG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLSQYKAAGIQRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDINNFVRKANAGADSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A371J944|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Romboutsia weinsteinii|TrEMBL
MSLLQEVLERGEFAITTEMAPPKGTDLSHLVECAKPLVGRVHAANVTDFQSAVMRTTSLA
TCKLLKDVGLDPVIQITGRDRNRIAIQGEMLSAGVFGINNMLALTGDHTVVGDHPQAKGV
FDLDCVGILQTAETLMSGEDMVGNKLKGSPDFFLGASVTPEYTPIEVQLLKMQKKINAGA
KFFQTQAVYDVEHMREFRKHTKDMNCKVLAGIVPLKSPGMAKFMTANVPGIFVPDEQIER
LRAAGKENWVTEGIKMAGELIRQLKEEDLCDGVHIMAIGAEENVPAILDAAGI
>A0A3M8ETJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium|TrEMBL
MNVIDRLKTEILVGDGAIGTMLYAKGIPLDANVEHLNLIRPALVTELHREYLAAGARLIE
TNTFGANWTKLSAIGLEKREREINLRGAQLAREAAAGADAFVAGSVGPLIRVKGDERELS
ETETTAIFRSQVSALAEGGVDLLVLETFTELTQMRCALAAARETGLPVVANMAFLENGRI
AGGLDVERVVLELAAAGADVVGANCGAGPLEILGTIRRMARVTALPLAAYPNSGFPEYVN
GRHVYRTTPDYFADRAMEMVEAGAALVGGCCGTTPEHVRRMVERLAGMRPVVRSVVVPDL
PVEARLEEATAPEGFLARWGKEPVVTVELDPPKGLDCAKIVEGSRALKAAGADAINIAEN
PLARIRMGNIALGSLIQREAGIEVIVHVTCRDRNLLGLQSDLMGASLLGIRSILAVTGDP
ARIGEQAGATSVYDLNSFTLIKLLADLNAGVNALGNPIGRGAGFTIGCAFNPNGQRMDVQ
ADRLAKKVANGARFVQTQPLYDLARLDDMLERTAHLGVPVLPGILPLVSERNCEFLHNEV
PGIVIPEEIRQRMRGKEKDAGAREGLAIAKEFIDAARHRVGGFYLIPPFGRYEIAVELTR
YIKTEHTPS
>A0A8H7GSE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metschnikowia persimmonesis|TrEMBL
MKIAEKLKQAHSCANPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSLLTNEMVYTAQLTLGLETCMHLTCTNMPVSYIDEALDKAYKAGCQNILALRGDPPLD
GSESTGDFRYAKDLIAYIRKNYGDHFNIGIAAYPEGHPEEENSANLMQYLKEKTDSGADF
IITQMFYDVENFINWCREIRAAGIHIPIIPGIMPILTYSAFVRRAKWSQVKVPQHFFDAL
DPVKDDDFVVREIGTQLVAEMCQKLIDSGFVNHLHFYTMNLERSTIMLLETLNLIECVKE
NEAVGDVLPWRKSLHPNRSKEAIRPIFWQNRKYSYISRTSGWDEFPNAFETVAKRALELW
GCPQEVKDLANIVVKYLKNDVKALPWSDGPIGSDTDILKESLIKLNENGFITLNSQPALS
AVRSNDKIHGWGPKNGFVYQKQYLEFLVHKDLALKLVDAVEDHNQRDPTGLITFYLVDKE
GRLTTNSKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYSLLDEWVTIFHLKAIG
ELVAPEKVEAFSKFLTGFGNDYVLCNLVNNDFTSDNNVMFDLLHGLGASH
>A0A8C4HDD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dicentrarchus labrax|TrEMBL
MVNQVQRGDGSWQSSKSDSSGASNSGGESSKDSSRCSTPVLDADRSDRLRDKMRKRMESG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGGYPTGHPEAESYEGDLRH
LKDKVDAGADFVITQLFFRADTFLKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSK
LEVPEEITKVIEPIKDNDAAIRNYGIQQAVDMCRLLLDSGKVPGLHFYTLNREVATMEVL
RQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSS
SPAFGELNDYYLFYLKSKSSKDALLQMWGEELINEESVYEVFTCYITAQPNSRGHKVMCL
PWNDEPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYL
EFFTSSENVTALLKVLKKYEPRVNYHIVDVHGRNLTNAPDMQPNAVTWGIFPGREIVQPT
VADPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIRDNYFLVNLVDNDFPLENCLW
QVIDDMFELLDASPEQLNDGTLSE
>A0A417Q3Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. OM08-7|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A1H6R9W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudospirillum japonicum|TrEMBL
MQQVAVSFEFFPPKTPAGETKLIQVRDALAQAQPEFFSVTYGAGGSTRERTLSTVASMRQ
AGVNTAPHLSCIGSSREELASLLDLYKAQGINRLVALRGDLPSGMGDPGELRYANELVQF
IREHSGDHFHIEVAAYPETHPQAVSFEKDLQNFCRKVEAGANSAITQYFFSADAYFYFVE
RCQEEGVQVPIIPGIMPMTNYSKLARFSDACGAEIPRWIRKQLEAYADDSDSIRAFGEEV
ITRLCETLIANGVPAIHFYTLNQAEPSLALVRNLGLMPNKSQ
>A0A4Y9PK62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. CT_GayMR20|TrEMBL
MVFGPCGGVRDDERCELGEHRCVFVGAPLVTWPGAPAPRPAAQPGGLLARAAAGPVVLVD
LSVRPFDTGSVRRVVGILRGVSDALLVGEHANRPDFPPTMVAAEVLDAGGRVWTTLTCRD
RNRLVLEQELVGLAALGVDGVLCVTGDGRGPGVRRGASQVFDLDGVRLAALAAGTGLPVA
VPESPEAPPVALRPARVAQKERAGAQLCVLNHVSSPARVGQFVAAARDAGATLPFVAGVA
VYTDEPSARVLQRFPGLHLDGDVVERVLAAPDPREAGIAAAVEEGRALLAVPGVAGVNLS
GTGSGRGEDDGAAIKAEVAGRLRGTA
>A0A657LSP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararhizobium antarcticum|TrEMBL
MPIHTLYPAERGNLTLSYEYFPPKTDEMETQLFKTVAELAVFSPAFVTVTYGAGGSTKAR
SLTTVRRMIRETGLANTAAHLTCVGATKSEVDAVVADFAACGVRHFVALRGDPQGGIGSA
YTPFPGGYENAAALVAGIRAAGDFEISVSAYPEKHPESPDVAADIDTLKRKVDNGATRAL
TQFFFDNDDFERYLERVRRAGITIPVVPGILPINNLAQVRKFAGLCGARVPDAVITRLIH
LDEMPEERIKEATHIAAEQIVDLARRGLRDFHLYTMNRSPLIEAVCDLVGFERQASAARD
NAAAGAAA
>A0A126V1L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falsihalocynthiibacter arcticus|TrEMBL
MTTTQTPRISFEFFPPQSLEASFRLWDTVRALAPLEPSFSSVTYGAGGTTRDLTHEAVAT
IHKNYGLNVAAHLTCVDATREETMQIAQSYSDAGVTEIVALRGDAPKGAESFTAHPDGFS
DACELIEALADTGKFKLRVGAYPEPHPDSPSSQADVDWLKRKIDAGAHSAITQFFFEADT
FFRFRDACVKAGIDAPIIPGILPIQSWKGAQRFAARCGTSVPTWVAEAFEKAERDDRTEL
LATSLCTELCSDLLEGGVEDLHFYTLNRPERTRDVCHALGITPSKVLQNVA
>A0A8H7PEJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mortierella isabellina|TrEMBL
MKIVDKIAKAQEEGKPFYSFEYFPPKTELGVANLYDRMGRMAQIQPAFISCTWGAGGSTA
DRTIELCATAQSSYGLETLMHLTCTNMGKDKVDLALAQAKNAGIQNILALRGDPPRGQEY
WAPCDNGFCHAIDLVRYIRQQYGDYFCIGVAAYPEGHVDSQDKTKDVLYLKEKIDAGADF
VVTQLFYDIDTYVKWQKQCRDAGISVPIITGVMPIQSHQAFRRIINLCNTNVPPKILEEL
NEIKADDQAVKDYGVKLAAKMVSELYHEHHITCFHFSTLNLEKSVRLVLQELNFLPKGVT
TASEQINPVNMNASSLLAEAHRAETWDEFPNGRYGDSRSPAFGDNTYGAGVVLPTSKASA
KWGYPKQAGDITQLFLAHINGTLQTLPWCDEPLQTETDAIRQSLAVLNKSGLWTVGSQPS
VNGAPSADPVFGWGPAGGYVYQKEFIEFFVSSDKLPSLLERLTQDPYITYYGANRKGESK
TNVHDRESQNAVTWGVFPGKEIVQTTIIEEAGFNAWRVEAFELWTEWEQQYPPESDSSKL
LKHLGDDVWLFNVVHNDFQNPGQLFEVILG
>A0A7X2M6L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. BIOML-A2|TrEMBL
MKIKDRLNENRIHISFEVFPPKTDAGYEKVQEATDRIAALNPDFISVTYGAGGGTSKNTA
KIAEHIKEDLGIESLAHLTCASSTKDEVRSVIGSLKELGIENILALRGDIPADMQFPSED
RFHYAYELVEEIRKHGDFCIGAACYPEGHVENEHKADDIKYLKQKVDSGVDFLTTQMFFE
NDIHYNFLYRIREAGITVPVLPGIMPITSAKQMKRSCELSGTVFPRRFQAILDRFGDCPD
AMEQAGIAYATDQIIDLLANGVRNIHIYSMNKPEVAEAIMSNLSEIIKC
>A0A1Y0I2K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulosimicrobium cellulans|TrEMBL
MPPRRPDAAPKFWETARRLVATHPDFVSVTYGAAGTDRATARQVVGRLLQGTPVLPIAHL
TCVGASREDVEEVISDFLDEGVRSFLALRGDPPRDQPDWQPAPDGVRSSTELVALLREVE
ASRCAADPAAALRGAARPLTIAVATFCDGNPAAGTTRTQEVRRLWQKQQAGASFAITQLF
YDASSYTDFVAEARAAGVTIPILAGLLPTTEPARLRRVEELTGVRAPQHLLDALDALPDP
EAQHAYGIAYSVDLAQRVLDAGAPGLHVYTFNKHRAALDLLEGVHLGGGSAGTGGSASAA
AAPLVPDLASGPWVTGTSLPTTSAATHGTPV
>A0A2N3UD94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter ramchanderi|TrEMBL
MKVTEHFQNANGKTLFTFEILPPLKGENMKTLFSHIDPLMEFKPPFIDVTYHREEYVYKQ
RENGLLEKITTRKRPGTVGICAAIQNNYKVDTVPHLICGGFNKEETENALIDLHFLGIDN
VLVLRGDCVKSEQRFVPEPGGHHYASELIQQVVDMNQGCYLDEEQVSNSCTDFCIGVAGY
PEKHFEAPNMRSDLRWLKKKVELGAEYIVTQMFFDNQKYFDFVKHCREEGINVPIIPGLK
PMTTKTQLTLLPSLFHIEIPCDLADAIEACPDNKAAAQIGVEWAIQQSKELMEFGVPCLH
YYSMGKSESVRKVAEALF
>A5PAW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. SD-21|TrEMBL
MSPTLDQMREAQRALEAPLFSGLPGDIDVSFEFFPPKTEKMAETLWSSVKTLEPLDPRFV
SVTYGAGGSTRERTHDAVRRIVAETGIPAAAHLTCVQATREEVDEVARQYWEEGVRHIVA
LRGDAPDAQAGYAPHPGGYENAADLIAGLTKIADFEISVAAYPEVHPDSPDRQSDLDNLK
RKFDAGATRAITQFFFEPECFFDFRDKAAAAGIDGEIVPGIMPVMSFAAVQKMSGLCGTA
IPDWMEGLFDGLDERPAARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRPKA
>A0A1T0AXX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Haemophilus] felis|TrEMBL
MSYAKQIETLNQHIADLNGELNISFEFFPPKNEKMETLLWDSIQRLKVLKPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLEAAPHLTGIDATPEELVEIAKDYWNSGIRRIVALRGDEP
KGYAKKPFYAKDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIESYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAVTNVKIPNWLEKYYDGL
DDDPTTRNLVAATVAMDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGIRPSL
>A0A0P7JUU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MRKQTFSVEIEANPGDLRQMKHYLHKWKPDFVSISNLSRYSYEEMVQCARYIQTDLHIPV
VIHLTGLTHTKEEVKKAFNQLMDLNIRNFLLVRGNIHHNMHIEDDFNYASDLIKYVNQLD
TDSKINVVAGCYPDIHVLADSLTEDIEYLKQKVNSGVDSLISLMCFDNKRIYKFLDKSRE
FGINVPIRIGIMPITDPFKKDYLAHNDVKMPEFSKEEDNLLEDGIDYAVNQINDLYEHNV
NGIHLYTHNDWMVSDRVFENIKQNL
>A0A0M9D2T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MPLQYSFEITPNIDLDNLDGLLKLNPEFISITDRNHDMDNLLQSIQIADYIHANSSVDVV
IHLTGIDKDEKRVQEMIDLMEEHGIHSLLALRGDKISQNDTAVTFPHADRLVEFIRQQYP
HVNIVGTCYLNSSDEEMKWLRQKVEKGCTKLISQFSFDVNDYVDYLNQIQIDTPIWLGIM
PVISKSQAQRMLNLTHSTAPDELNALMNQHEDEFGEDGVQYTAGMIDQIKQAGANHIHLY
SLNNASNTKKIINKI
>A0A0Q5G6E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. Leaf130|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLRIVHQELQPLNPDFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIRQHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>I1DT04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rheinheimera nanhaiensis E407-8|TrEMBL
MAFANAQYLEAINRNLQDVEGKVNVSFEFFPPKTAQMEQTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASKDDLIAIAKDYWQNGIRHIVALRGD
LPPGTQSKPDLYAADLVEILRSVADFDISVAAYPEVHPEAPNAQFDLLNLKRKVDAGASR
AITQFFFDIEKFLRFRDRCAAIGIDVDIIPGILPVTNFAQLQKFASLTNVAVPQWMHKAY
EGLENDATTRNLVGANIAMEMVKVLSREGVDHFHFYTLNRSELSYAICHLLGVRPQRAL
>A0A0H2P3J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIANTIH
GEYGIPAVAHLTALYSDEAKIDEALDMFEAAGVSAVLALRGDYIDGEEPVGRFNHASDLA
AYIHDRKPDLKVFGACYPEGHYSAASLDEDIGNLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGAKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGII
YASDQIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFTVE
>A0A3N6I199|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ADI96-02|TrEMBL
MDSLATAAGSAVAPLLEDFSLEMTGKDISGLDGARACIPPGTRINITFLGNEDPGTRLAA
ARAVRRSGCVPVPHISARRLRSRSELDAFLAALRSDGTADNVFVVGGDPATPHGPYDDSL
ALIRSGALRAHGVRHVGISGYPEGHPAIAHPVLWSAMEDKTAALAGDDLSGDIITQFGFD
ADPVLAWVEEVRGRGIDAPVRIGVPGPAGIRRLLTYAARFGVGTSASIARKYGFSITNLM
GTAGPDRFIRALAGGYDPTRHGVLKLHFYTFGGIENTSRWIADFRAAEGVPSTEGTGGLH
RSLP
>A0A0E4BI78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella forsythia KS16|TrEMBL
METVIDLIKNSQRTAFSFEILPPLKGNSIQSVYQVIDKLREFEPKYINITSHHSEVIQRV
EPDGSIRTVNLRKRPGSVAIASAIQNKYGITAVPHLVCKGFTKDETEYGLIDLNFLGVNN
LLLLRGDIKRLDLTKDPKRCHDHATDLQHQVNDFNRGIALDGSAIEDIETLFSYGMACYP
EIHEEAPSMESDIRYAKMKVENGAEYLVTQMFFDNDRYDAFVARMRAEGVTVPIIPGIKP
IVFKDQLTVIPKIFHCTFPEPLTQALRQCKNDDEAKAVGIEWCIAQCRDLMKRGVPSIHF
YSFMASDSVRQVAKIIY
>C2EUU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limosilactobacillus vaginalis DSM 5837 = ATCC 49540|TrEMBL
MTTLSYEVFPPNSTVGINHLNQVLTSLRDLSPDFISVTCNSNTKQLAHETVRVADYVEND
CQVPAMAHLPAWYLSREDVDRILEQLRVCHVDRVLVLRGDERPKLEKKTDFAHASDLIAY
IKQNYPDFQITGACYPEKHPESLSMVDEIQHLKLKVESGCDQIITQLFLDNHSYYRFREL
CAIGGIDVPIIAGIMPVVNERQANRILRTSAVTVPEKFKDILAKYHDHPQALKQAGITYA
IDQIVDLVTNDVSGIHLYTMNHSDTARQVKQNIGSLFRVCC
>A0A177H754|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium SB2|TrEMBL
MSTPEISFEFFPPASLKDSFRLWNTINALEGFQPKFISITYGTGNKPRALTQDLVETLLE
HKDLTVAAHLTCVDMSAESTLNLVRSLAAKGLKDIVALRGDPAPDHGGAFRPHPLGYQTS
CEMIAALKNLGGFKIRAAAYPQGHPESRSQAADLDWLKRKFEAGADEAITQFFFEADDFL
RFRDACVKSGIDAPIIPGILPIENWIKTRNFAKKCGVSVPLWLEEAFERATRDGRHDLLS
TAIGTELCDTLRSEGVDTLHFYTLNRPELTRDICLALGLTAKPSLKAVA
>A0A7Y9ESH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium pseudoresistens|TrEMBL
MPVDPPRIADAGRADSTVPFSFELYPPRTESSTQALHETVRTLAAAGPRFLSVTYGAGGS
TGGRSLEVLRFIREHTDVEPLAHLTCVGNTYAGATTLIREFLDAGILSFLALRGDPPFGS
DEPFLGDLESAAQLVQLIDRVQAERAPYEEQAVPGAPGAVRVSPRRRVSIAVAAFPKGHP
RSTHRTQDVESLLAKQAAGATQAITQLFFHADDYLAFVERARVAGVTIPILPGIMPITSP
ARLARVLELTGEDLPGELAVALEVEPTAEGRAEIGIAWAAELVRRVVEGGAPGVHLYAFN
QHTTVLRVLAEAGILQRTAVH
>A0A226QQA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parageobacillus galactosidasius|TrEMBL
MGLLQDLKERILIADGAMGTLLYSHGVDRCFEELNLSKPEDIIHIHEAYIAAGAEVIQTN
TYGANYVKLARYGLEDEVPSINRAAVRLAKKAAGNKAYVLGTIGGLRSINKSAVSIDEVK
RTFREQLFVLLNEDVDGLLLETYYDLEELQTVLAIARKETDKPIIAHVSLHEVGVLQDGT
PLSEALARLEQLGADVIGLNCRLGPYHMIRSLEEVPLPKKAFLSAYPNASLPDYRDGRLI
YETNTDYFKETALAFREQGVRLIGGCCGTTPKHIEAIANALTDRTPITEKVVKQRHVPIS
IQTNEPNAAPPLQDIVRKRRSVIVELDPPKKLGIAKFLEGAKALKEANIDALTLADNSLA
TPRISNMALGSIVKEQLGIRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKSLGQKTNFSIAAAFNPNVRHLDKAVER
LEKKIQCGAHYFITQPLYSERQIEEVYEATKHLETPIYIGIMPLVSARNADFLHHEVPGI
TLSDEIRSRMAACANDPVQSAREGIAIAKSLIDAAFDLFNGIYLITPFLRYEMTVELVRY
IHEKEQAAQERKVLHG
>A0A6A6UMC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microthyrium microscopicum|TrEMBL
MHISQKLAKSREEGRTTFSFEFFPPKTAQGIQNLYDRMDRMHSLGPSFIDITWGAGGRIA
SLTTEMVQTAQSAIGLETCMHLTCTDMPRSKIDGALDAAEKAGCRNILALRGDPPREKEK
WEATEGGFRYAKDLVTYIKKHHEDKFDIGVAGYAEGCEDNEDPDELIDHLKEKVDAGATF
VVTQMFYDVDIFIAWVRKCRAKGITVPIIPGIMPIHTYAAFLRRAQWTKCHVPDEWMEKL
DKVKNDDTEVREVGKLLLVKMCQKLIAEGISHLHFYTMNLAQATQMVLEGLDILPDLESP
TIKQLPWRQSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDARSPAFGELDA
YGIGLKGSNEHYQKIWGHPTSVKDIADLFVRYMQGKLSSLPWSEQGITNEADTIKANLVE
LNRRGILTINSQPAVNAAQSSDPTFGWGPKNGYVYQKAYLEVLISPELHSELITKMDRDA
NITYYSINKAGDLTTNASGDGPNAVTWGVFPGKEIVQPTIVERVSFLAWKDEFFRLGEDW
GECHPKNSPSRYVIEGLMETWFLVNIVDNDFHQSHSIFPLFDGMNLKDIDKPMYEI
>A0A6A6UMQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microthyrium microscopicum|TrEMBL
MEKITDKIAALADDTPFFSLEFFPPKTAAGLSNLQARLARMSQALRPLFVNITWGAGGST
SSKSLELAEFTQQQLGLTTCLHLTCTNMSQRLIDEALSRAKTLGIRNILALRGDPPRNAE
YGDPNEGAQQQFVWAVDLVKYIREQYGDYFCIGVAAYPDGHADTSHPERQDAEFDLPYLV
EKTKAGADFIMTQLFFDVEAYRKFEAMLRGDESGVFKGIPIIPGLMPIQSYQVVRRVAKL
SHAKVPAELMTRLDAVKSDDEEVKKVGVDILSEIIEGLKKMGTPGKQGFHFYTLNLEKAV
SQIVERNHLIKELTVEDLPSEVIVSPSSTLTPPELGSFDRRRLSSGPQNRVVVEKLTALS
NQDYEITQKDAGKRDDKPLAPKTALEISEGEGSLGREATWDDFPNGRWGDARSPAFGEID
GYGVSLHVSIPEAIKLWGFPVTTNDINTIFQKHVSGELRAIPWSEEGLNPETSTIKEHLL
ALNAKGWWTVASQPAVNGVKSSDPVFGWGPRSGFVFQKPFVEFFISNTSWKAFREVLDKH
PEVTYFASNSAGAFEASDSEAVNPVTWGTFAGKEIITPTIIEAESFRAWRDEAFSIWREW
QHIYPPRSPTAQLLKDIESDYWLLNIVHHNYLEANAIWDLLLNETK
>A0A101ECD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorella sp. 60_41|TrEMBL
MALMTESRLERLLSQGHFVVSGEIGPPKHTSPEGILHHAELLKDYVDAANLTDNQTAIVR
MSSLAAAVHVLRAGVEPIMQMTVRDRNRIALQSDLLGAYSLGIRNVLCLTGDHQSFGNHP
TAKNVHDVDSIQLIKIVKDMRDDRKFACGEEIKEHEPRFFIGAAANPFADPFEFRVLRLE
KKIKAGADFIQTQCIFDMERFERFMALVRERGLHKKAYILAGVMPLKSAKAARYMQKSVA
GMIVPEEIVARIEKASDPREEGVAICVEQIKHLRNIEGVAGVHIMAVMWEEIIPTIVKEA
GLYPRPSVD
>A0A524JCN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIPDLLKPDQPSFSFEFFPPKNADGNAELLRTVERLKVLEPDFVSVTYGAAGSTREGTV
EVTTRIKHELGIEAMAHLSCVGETVEGLETLLERLHEAGIENVLALRGDPPRGEPDFKPP
EGGLRGSAELAAFIRSRGDWGIGGSSFPEVHPEAASRPADIAYAKTKVDAGAEFLITQLF
FDNAVFFQWLADARAAGITVPIFAGILPIRSYAGL
>Q1GFY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria sp. (strain TM1040)|TrEMBL
MTTPEISFEFFPPKNLEASFRLWDTVQSLAPLAPRFVSVTYGAGGTTRELTRDAVTTLHK
NSGLKVAAHLTCVSATRQETLDIADQYAAAGITDIVALRGDPPKEEGRFTPTADGFNSSV
ELIEALAATGKFNLRVGAYPESHPEAASQAANVEWLKRKLDAGADEALTQFFFEAESFFR
FRDACAKAGIDTDKITPGILPIENWKGVRRFAEACGTTIPAWLDEAFEKADRDDRCDLLA
TALCSELCTELLDGGVKKLHFYTLNRPELTRDVCHALGVKSKARLQNVA
>A0A2K8WXA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olleya sp. Bg11-27|TrEMBL
MKVTEHITKGEGKTQFSFEILPPLKGQHIQSVFDNIDPLMEFKPPFIDVTYHREEYVYKD
LGDGLLKKQVVKKRPGTVGICAAIQNRYNVDAIPHILCGGFSKEDTENFLIDLDFLNIEN
VMALRGDAVKTETYFTPEKDGNAFASDLVKQVSELNHAKYLDESLLNCSATNFCIGVGAY
PEKHMEAPSLDSDIHFLKKKIKNGAEYVVTQMFFDNEKYFQFVDKCRAEGITVPIIPGLK
PISTRKQLNIIPHRFHVDLPEALIKAIIKCKTNAEVRQVGVEWCIQQSRELEKSGIPLLH
YYSMGKSDNIKAIAEAIF
>A0A554PIS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ATCC 13985|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQTFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A2J9HED4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia glumae|TrEMBL
MKPIELSLEFFPPKTAEGVDKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLLAAPHLSCIGASKDNLRAVLDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRLEVAAYPEYHPQSRSPKLDLLHFAEKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFTQLMRFSEMCGAEVPRWVARRLESFGDDKESIRAFGADV
VTAMCERLIREGAPGLHFYTLNAATATKVVCERLGF
>A0A2G2JEX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanobacter sp|TrEMBL
MTTLSFEFFPTKTDEGTEKLLKVRDELAAFNPEFFSVTYGAGGSTRDRTYAIVKAIQERG
IAAAPHLSCVGDSTADLRSILKEYQDLGIDRIVALRGDLPSGSGLANSELRFANELVEFI
RNETGDHFKLEVAAYPEMHPQATNFEQDLQNFVNKVKAGADSAITQYFFNADSYFYFVDR
VQAMGVDIPIIPGIMPITNYSKLARFSDSCGAEIPRWIRKQLEAYGDNSESIQQFGEDVI
TDMCRRLLDGGAPGIHFYTLNQSEASLRVWRNLV
>A0A4U0R9P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus hibiscisoli|TrEMBL
MSTPKISFEFFPPKTLEASFKLWEAARALAPLAPDFVSVTYGAGGTTRQLTHEAVTTINR
QFGLTVAAHLTCVEATRAETMEIVQSYADAGITEIVALRGDAPKGADRFTPHPDGFANSV
ELIEAIAARGDMTIRVGAYPEPHPDSRDGDADVTWLKRKLDAGATSAITQFFFEADTFFR
FRDKCAAAGIDAPIIPGLLPVQSWAGTKRFAATCNTTVPDWAEEAFQLAALDGPEATRQL
ATGLCVDLCEQLIAGGVDRLHFYTLNRPELTRDVCAALGVRPQPGLEAVA
>U2YJT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenibius tardaugens NBRC 16725|TrEMBL
MSQSSTPFDGERPLDTPLFAGLPGDIAVSFEFFPPKSEKMEAQLWEAITQLAPLEPSFVS
VTYGAGGSTRERTHATVSRIVNETALVPAAHLTCVAASKGEIAEIADQYWEAGVRHIVAL
RGDPPPSDGGRFIPHPDGYAGAADLVAGLRKHHDFEISVAAYPEMHPEASSLEADLDNLK
RKLDAGASRAITQFFFANDAYFRFLDKALAAGITAPILPGIMPVTNFDAIRRMSANTEIP
GWLEATFEGMDERPGPRALVAAVVAAEQCRRLYAGGVRDFHFYTLNRAEQAYAICQLLGL
RPRGAHGTHKETAA
>A0A4R6P127|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia ignorata|TrEMBL
MTFDSGRGRSTPDRPAKQQSIVSNTPSVVQSLRTHSGTGVPFSVEFNPPRDAAGEARLWR
AVREFERMHPAFVSMTYGAGGSTRDRTVRITGALAQETTLLPVAHLTAVGHSIAELRSLV
GSYADSGICNVLVLRGDPPGDPLGEWRKHPEGVEYAEELVRIVRDLGDFHVGVASFPQGH
HRSPDLDHDTRHLCAKLRAGAEYSITQMFFDVEHYLRLRDRVIAMDPVEGAKPIVPELMP
ITSLRTVARAEELSGRPVPADIVARLTRAAGTGPEEDRAAVRAEGIQIATEMAQRLIDED
APCLHFITLNFAKATSEVLANLGYGVTAAPLSA
>A0A174ZDZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospira eligens|TrEMBL
MKYTGTAGILYDRLKSEILVADGAFGTYYAKKYDTGSLPELANLQASDRVLAIHKEYIEA
GAKIIRTNTFASNTVCLGVGFDEVRNNIKNAVDIAREAVKGTDVLVAADIGPIPGENMIE
KEHIEKEYVDIVNVFKECGVDIFVFETFPELGFIDKAIENAGENGFVITQFAINQFGYSS
AGFSARKLIEEAGKNSYIDACGFNCGVGPGHMKKLVQSLINRNDKYFAVLPNAGYPQVVS
GRMVFDDNNAAYFSQIMHDLAEDGADIIGGCCGTTPEYIRQMVLKTADVVHKKNASIEEE
ITEKKTANDVSFYKGKEGRKLIAVELAPPLGIDDEKIMDAAFLMKESGVDVLTFPDSPSG
RTRADSILMAEKVSRETGMCVMPHICCRDKNAIAMRSQLLGAHINDINNFLVITGDPIPS
VVRASVKSVFNFDSVGLMNIISDMNQEQFAGEPVIYGGAINQGRVNFKVELERVKKKMEA
GATFFMTQPVFSDEDIDRLRQIKEQTGARILCGIMPFVSLRNATFMKNEMTGINVTDEIL
SRYRADMSKEEGEETGIQIAREIIAKTTDFVDGYYFSFPFNRVHMLKKIIGKNNQ
>A0A8E2VMR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum kholense|TrEMBL
MTAPRVSFEFFPPQSLEASFRLWEAAQALAPLKPAFVSVTYGAGGTTRKLTHEAVATIHN
HYKLNVAAHLTCVDATRAETLEIADSYAAAGVTEIVALRGDPPKDQGAFRPHPEGFANSC
ELIEALAATGKFRLRVGAYPDPHPEAGSADADVLWLKRKFEAGADSAITQFFFEAETFFR
FRDACEKQGIDGAKIIPGILPIEKWAGVRRFAERCGAHVPPGIDEAFQTAIRDGREELLG
KAMATELCTELMDGGVRDFHFYTLNKPYLTRDICHALGVLPEAHLEKVA
>A0A2E5G5L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaeraceae bacterium|TrEMBL
MARTTSIPKMISGKVDPWQKPTLRQILQRGEKFAVAVELVTSRGVIAERSGQRVLDLARS
LSSHPEIDAMSITDNPGGNAMLGADVLGTDLISRGQEVIIHLACKDWNRNAIQSRGWELA
SAGFHNVLALSGDCPVSGFEGQASGVFDIDSVGLLKMFDDMNKGLKYPSRISDKMLTMKR
TNFFLGTVVNNYKRYEREVMPQYFKLAKKLESGAGFVINQLGYDSRKLDELQRYMALKEM
DVPVLANVYILSGRAAQFFHDGGFPGCFVNDTLFDLSQKHARSPDKGKSFFFEFAAKQVA
IAKGLGFAGVYLGGHLNADEFARVLEIEKQFSADDWKTFARQIQYGHTDEFHYFEQDRKT
SLTSNQVNRYYLASKTADGQKQARQQISLDYKLNRLVHNQVFKKGTKGFNAGRRISLKIL
DSSVGMQKIAHRMEHALKILSFDCRDCGDCSLPDIAYLCPESQCAKNQRNGPCGGTRKGK
CEVGEKDCIWARAYDRLKAYGEEEQMLDRPVVYKNGALQGTSAWTNTFLERDHHSKNS
>A0A0H3D0I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis mediterranei (strain U-32)|TrEMBL
MTSVIERLRGDGPKFSIEFFPPRDTADEAVLWKAIRELEPYDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYASVGVRNILALRGDPPGDVYGDWI
PHPEGLQYAEELVQLVRSLGDFCVGVSAYTYGHPRSPDLETDTKYLVRKLRAGADFAIAQ
LFHGAEDFLRLRDRVAATGCDVPVLPGVMPLTTWRTLQTTIKLSGAPAPRKLLDRLEPLA
EDPKAFRAAGIDVTTELCEKLIAEGVPNLHFYTFNRSKATREVIARLGLVPARA
>A0A5C1C5S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter chengduensis|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A0A2HUY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp. Tol-SR|TrEMBL
MDLKTNSRLEKVLKSGQLAVTSECGPPRSSAPEGIIKKGELIKNHVDVINVTDNQTSVTR
LCSLAACVHLKLQGLDPVLQMVVRDRNRIALQSDILGAASFGINNVLCLSGDHQSFGDNP
QAQNVFDIDSMQLVQTVRRMRDEGRFLSGDEIKVPPNMFVGAAANPFADPFKIRVPRLAK
KVAAGAEFIQTQCIYNVDKFELWMQGVRDRGLHEKVFILAGITPMRSVGMAKYLRKSVPG
MDVPEELINRLAGVEKEKQAAEGITIAVETIQRLKEVKGVAGFHIMAIEWEEKVPEIVER
SGLFPRPVID
>A0A554RRN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. KBS0712|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPQFCSVTYGAGGSTHQGTFGAVQEILAE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFATKMKAGADSAITQYFFSPEAYFRFVDD
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLQAGGAPAIHFYTMNQSAATLAILERLD
>A0A3D8NKF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. IB2014 011-12|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A1R3TCH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium rosae|TrEMBL
MTKTEVDRQNSGNFKLSFEFFPPKNADMDVQLWETVEELSRWNPDFVSVTYGAGGTTKAP
TLVAVDRMISVAGLSTASHLTCVDASKQEVHDVVEELRGIGVKHFVALRGDPSTGPGTAY
KPHPDGYENAAALVRGLREIDDFQISVSAYPEKHPESESTDVDIDMLKRKADNGATRALT
QFFFDNAMFEQYMERVTKAGITIPVVPGIMPIQNLTQLKRFAGRCGTTIPAFLDERFAGY
DENPVERAKVAADVAAEQILDLQSKGINEFHLYTMNRAPLVNAVLENVGFRPLKQSAA
>A0A2K8K8R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobaca barguzinensis|TrEMBL
MPAPRVSFEFFPPKTLEASFRLWDTVRMLAPLSPSFVSVTYGAGGTTRQLTHEAVTTIGA
QFGLNVAAHLTCVDATRDETLAIADSYAQAGVREIVALRGDAPKGQARFTANADGFANSI
ELIEALSATGHFNLRVGAYPEPHPEAADTLADVRWLKRKFAAGADSAITQFFFEAETFLR
FRDTCAREGITGRIIPGIIPIENWSGIRKFAKATGASVPAWLDEAFEKATRDGREDLLAT
ALCTELCDKLVREGVEDLHFYTLNRPHLTRDVCHALGVVPQVSLEKVA
>A0A087PPU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter malorum|TrEMBL
MSLSRLSVELIPRSEDALAQDVTSVKTLFPAADTLNIPDLMRFPLRSWDAAAVTMPQFGT
VVPHVRAIDIAPGAPLPGSTLPGLKEVLVVHGDPPADLAHRTYPNSTESIIRRYRKEAPH
LRIYAAFDPYRRAPWRELEDIARKKDAGAEGFFTQPVFDLKLFDLCREWLQDEQVFWGLS
PVIGPRSRSYWETTNHVVFPKDFEPTLDANIQFAQSVLRQLSQDQGCAYLMPLRVKLDQY
LPPLVSALTA
>K9TZF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroococcidiopsis thermalis (strain PCC 7203)|TrEMBL
MTEQYITDRDSRNSFRTAVKSGKFLITAEVTPPKGSDPTRMIEVALALRNWVHAVNVTDG
SRAVLRMSPLAAATILSQHGIEPICQMTCRDRNLIAIQADLMGANALGINNILALTGDPV
KAGDHAQARSVFDLEAVRLLQTITKLNQGFDYNGKGLCDGATQIFPGAAVDPQLASWSGL
QRRFERKVAAGAQFFQSQMIVDFSRLEKFMSQIAAKFNKPILAGIFLLKSAKNAQFINQY
VPGVNIPQAIIARLEQATDPLHEGIVIAAEQVRLARQVCQGVHIMAVKREDLIPQILEMA
EISPQGQSVQNVATTRIALAEPLLRRNSHNTNNFHTRL
>A0A7T0NW92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas sp. LL1|TrEMBL
MNISFEIVPRSLEAFDEQYAFVEKLDDGINIINVPDIQRFDTRSWELATRIDRSKFRFIP
HFRAIDFKIDGGELFRIIEEYRLDSVLLVSGDPPEGLKRAYYNTDVVDLIRAVRQYFPKL
AIYAGFDPHRQGLQDECDYTQRKADAGATGFFSQPFYDKRLIEIYAEHMHGLETYIGISP
ITTQASKNYWEVKNKVRFPKSFRPDYDWNVEFANQVIASAAASGLNVYFMPIRIDLERYF
GGIRLGM
>A0A7H8R506|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces rugulosus|TrEMBL
MEKITDKIAALPPDGHYFSLEFFPPKTQMGSVNLQARLERMAQALRPLFVTVTWGAGGTT
ATKSLELAEICQRQLQLTTCLHLTCTNMNRKLIDDALEEAKALGIRNILALRGDPPRSGE
YNVEGDDDSNNDFTWAIDLVRYIRRTHRDYFCIGVAAYPEGHPGESQTDVQDPERDLPYL
VEKVQAGADFIMTQLTYDIEAYTKFENTLRTHPSGALKTIPIIPGLMPIQGYKILTRVTK
LSGAHIPPPIVSRIEAVKSDDEQVKQVGVDIVSEIVNDIKELACPGPRGYHFYTLNLEKA
VSFVLERCDLIPPYNEPDEVAIEDVAIEVTQMNGTDGAKPAFARRRASSINSGPHNRVIV
DKLHVPVDQQSEHSSRKSITYETLASSAGVPALNPPPRSTQLQISEGIGSLGREATWDDF
PNGRWGDARSPAFGEIDGYGPSLHVNANVARQLWGFPVSNSDISTLFKKHVSAQLYIVPW
SEGGAAEESNLNAETETIKPQLLKIIEKNWWTLASQPAVNGLRSDDPVFGWGPPGEGFVF
QKAFVEFFCPNADYKNKIKPTLLKNGSNEFAWFATNGAGDFESSFSIPENTTPDGSPTDA
PAEADEDYVEVSDSTGMAVTWGVFRGKEITTPTIIEDVSFRAWGEEAFRIWDEWRRIYPR
GSATERFLGEIKNDVWLVCVIGQRFGAGTEPGSEEEKAETHMLWDMLVNA
>A0A6J4JZL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Friedmanniella sp|TrEMBL
MVHGPCGGVSADGTCELGDRRCTFVDVPVVSRQPVLGAGTGTAEPTPTDLRGLLRRGRVV
VADFPGVALDAGSVAAVGEVLRGTVHAVLAGDSPRSRVQFPPAYRAALIRASGLHAWTGL
TCRDRNRVALEGELAALAHLGVDAVHCVTGDHPALGSRADAAAVFDLDSTQLAELAVRAG
MLTSVGESPTAPPLDQRAARLVEKLGAGAEVCFVNHCGGARPVRAFVAQVQDRGADPWFL
ACVPVVVDVASAELLASFPGFVLPPGFLDRILRSDDPEEAGIAAAVELGEELMTVPGVAG
VNLSGGSAPGAELPFARALAEIGRRLGVRAAPTSAR
>A0A426GYU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peribacillus simplex|TrEMBL
MNFRKEVKERMLVGEGAMGTLLYSNGIDQCYEELNCTNPDQIVSIHRAYLEAGADILQSN
TYGANFNKLKRHGLEDEVSRINRQGVILAKKAAKGKAYVFGTIGAQRSIRKSDLSIEEIK
RGFREQLYSLLMENPDGILLETFYDLEELETVLQIVKNETGLPIIANVSMHELGNLQNGI
HLNEAFQKLEQLGADVVGVNCRLGPHHMIRALEEVSLPKQASIAIYPNASLPDYVDGRLV
YKAVPEYFGSSALELREQGATIIGGCCGTTPLHIQAVKNAIGSLVPVKEKITKTREIEII
EVIDRELEIPLYEKAKTERTILVELDPPKKLGIESFMTGAEVLKKAGVDSITLADNSLAS
PRISNDALANLLKNQLNVTPMVHITCRDRNLIGLQSHLMGLQTVGLNELLIITGDPSKIG
DFPGATSVYDLSSFDLISMVKQFNEGLSYSGQSLGQRANFKIAAAFNPNVKYLDKAVQRM
EKKVACGAQSFLTQPIYSVEQIEEVYEATKHLETPIFIGIMPLTSTRNAEFIHNEIPGIK
LPDNVRRAMALAGDDPVKSRVEGVNIARELVDAAREKFKGIYLITPFLRYEMTAELTKYI
RKVDSKQTSEVAVHE
>R4JXI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium pasteurianum BC1|TrEMBL
MLKSKILNRDMGIVTYAITPPKKSNSQEKIIEISQRHVERIKNIDIDGLIIYDIQDEGDR
LQDKRPFPFLETINPAEYSRKYMQELTVEKIIYRCVGKYHENELRESIASDLQEDKFSVF
VGAASREQEVKLKLSEAYNIREKLEDKLTLGGVVIPERHTRNKDEHMRIINKTNKGCKFF
VSQVIYDIEVSKNLLSDYFYYCKDNHMEMVPILFTLTPCGSIKTLEFMKWLGINVPKWME
NELIHSNDILDKSINLAKNIFEELLDFALDKGIPIGCNVESLSIRKVEIEASIQLVRDIK
LIIENKLKGYKYEKLKIINMN
>A0A7X5YNP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas alba|TrEMBL
MSAAALSLAEARALLLSPLGPVARAGQDSSRPRVSFEFFPPKSDEAEAALWKAVTRLAPL
QPDFVSVTYGAGGSTRERTHRTVQRILDETDLTPAAHLTCVEASRDEVDAVIDGYRASGV
RHIVALRGDPPGGSGIGGAYVPRMDGYANATELTAAVAGRGGFEISVGCYPEGHPESPSL
AHDIDVLKAKVDAGATRTISQFFFDIDAFLRFRDRVRAAGVTIPIIPGVMPVTNFTGLKR
MSAGCGASVPDWLAAHFEGLDADPETRKLIAASVAAETCARLQEEGFADFHFYTLNRADL
VYAICRVLGVREQRAHA
>A0A1F2RS41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium RIFCSPLOWO2_12_FULL_54_10|TrEMBL
MNNLSRRFLEELQQRVLVCDGAMGTVLYAKGIPINRCFEELNLIMPSVVKEVHESYHKAG
AEIIETNTFSANPVRLESFGLREKCRDINAAGVRLARQVVGDKGWVAGAVGPLGVRLAPL
GPCSPNQARAAFQEQMLALAEAGADLLMLETFQDLEEVAQAIAAARAVCDLPIVAQITID
DEGHLPAGTPPEDFTPRLTALKPDVLGCNCSVGPSVMLETIQRMASLTALPLSAQPNAGL
PVNVSGRNIYLCSPDYMAGFIARFIQSGVKLAGGCCGTTADHVRAIAEAVRSVQPPRPKI
GWTSVASKESDRSLPPLPVSDRSPLAAKLAAKKFVVLAEVIPSTGCDPSQEIEGAQYLAG
NNVDAILVRDGSRSGARLSALVLAHLIQQRAGIETVLQYSCRDRNVIGIQSDLLGAHGLG
LHNLLLITGGHLVTDSYPDATAVFDVDSVGLTKIVSSLNRGVDLGGKFLGSQTGFWVAIS
ADPGAVNFEREMERITVKMQLGANCVITRPIFDIQNQERYLVAARELGIPVIAGVAPLTS
LRHAEFFANELQIPVPESIMNRMRKAASGEAARQEGLRIAAEIVAWLEDRVQGVLITAPL
GRYDSAIEVLSALRSRQKGSAAPEAAMQAAIQESAGRIKT
>A0A1G0NWM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium GWA2_54_16|TrEMBL
MKLDFRERLRRGPILCDGAMGTLLDLYEYSDRPHEINNIKNPDIVARVHQEYIDAGAEII
ETNTFSANRFRLSQFHLQDRLKEINKAAVEIARRVAGDRVYVAGSVGPTGKLLEPIGKIK
LLEARAAFKEQIEILLEGGVDLLILETFVSLNELDEAITAAKELTKLPIVAQKAFPEDGS
ILSGTFPLEVVEHLLSRGVDVVGANCTVGPQRMFSIIRTMYKDGVILSAQPAAGIPTLQD
GRSVYHTTPEYLATYARELIQSGVTMIGACCGSTPAHIRAMRKVMDELASQPVVSVAAPK
IGSPAGEKIAPVAQPEQAPDNRSNFARNVGKKFLVTAELDVPRGVDMSSVIEGARYLHRH
GIDAINITDGARARLRMSSVALSTMMQQEVGMEAMTHFTARDRNLIGLQSELLGAHALGL
RNVLCITGDPTSIGDYPHATSVFDVDSIGLIRAVRAMNEGRDLMGNTIIQKTSFLIACAA
NPKADDMDREVDRLEKKIEAGAEIVFTQPIYEMQTLEQFIKRCEQWRRPVMLGLLPLRSY
RHAEFLHNEIPGMVIPESIREALRRAGDKAAGVGVQLTQEFLKEARHLVAGAYLMPPFKR
YDVVPQVLEAVR
>A0A5R9PDI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomonas fusca|TrEMBL
MLPISFEFYPPKTDEQHAQFDRTVRKLKAHAPQFMSVTFGAGGSTLSHTPETVQRLRGEH
GVDGVPHLTCVGGSREEIRTLLKLYRALGCTRIVALRGDLPSGMARSGDLRYASELVRLI
RDEHGEHFHVEVAAYPETHPQSEDARIGLGHFKTKVEAGASGAITQYFYNADAYFRFVDD
ARAQGIDLPIVPGIMPIANFSQLRRFSEACGAQIPRWIDQRMRAFGDDAEAVREFAADVV
AGLCRRLVEGGAPALHFYTLNLAKPTQTVLQRLA
>A0A1H1W3D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiangella sp. DSM 45060|TrEMBL
MPGGARTIRELLAAGGRSFSFEFFAPKSEAAEVSFWQTMRDLERLQPTFVSVTYGAGGTT
REGTVRLTEGIARDTTLTVVGHLAAVGHSVAELRNVIGQYADAGVRNFLALRGDPPGNPQ
GEWVRHPEGFAYAEELVRLIRTHGDFCVGVAAFPDKHPRSPDLETDARFLARKFQAGADY
AITQMFFHADDYLRLRDRVAAAGGDAPIIPGIMPVTNVRQIQRFAQLTAADFPEPLARRL
LAVEDDPEAVRAIGVEVATELCERLLAEGVPGLHFITLNKSTATREIYQNLGVGALS
>A0A369ZL42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parahaemolyticus|TrEMBL
MSFATDIDHLNQNIADLNGKINVSFEFFPPKNEKMENLLWDSISRLAPLKPKFVSVTYGA
NSGERDRTHSIVKSIQQETGLIAAPHLTGIDATPDELRQIAKDYWDNGIRNIVALRGDEP
KGYAKKPFYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRAIS
QFFFDIDSYLRFRDRCVNVGIDVEIVPGILPVTNFKQLQKMAKITNVKIPNWMYRMYDGL
DDDPTTRNLVAASIAMDMVRVLSKEGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A2E1NRH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halieaceae bacterium|TrEMBL
MSALKQCMESLYYEVIPMKGYEAGLDHLNAGDKVGITCSPKQGIQYTLDTVAHIQPRGFQ
VTPHLAARQIKNRQHLADMVSFLTDQGVTSIFVPGGDVDVPMGDYDSSAAVLADLAEMDH
PFTKIGVASYPEGHPAIPDDVLFDALKAKQGIATHMVTQMCFDMXALLKWLKXMRDAGIT
TPVWIGLPGVMDRMKLFKTSLRIGVGQSAKYARKQKGLAGMLLRSSTYKPDALLKELKPA
MDDERMAVEGLYIFTFNQIDNTVQWSQEQLKRIK
>A0A5F2H072|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.220.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVVREFADMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKSAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A1E9ZUJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC070E08|TrEMBL
MSPRLSASAPLDQISEDTPKRPQRTALSFEVIPPRHDADAAKIDRLLATLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTEEELVGWIDTLVDAGVRGLLALR
GDLPEGGMPEGHLPHADSLVRLIRRWESDRVARLAAGRLAVGVACYPNGHAESATPDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTKVLDQLAAATSPEEEKEIGMQITASLAKSVMNAGADGLHIYTHNNPDITTDLL
HRIGVIP
>C7MUK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)|TrEMBL
MRRVVDRLSSTRCPTFSVEFFPPRNEAEETILWRSIRELEPLDPAYISITYGAGGSSRDG
TIQNIARVATDTTLVPMAHLTAVNHSVAELRNVIGHFAAVGVHNILALRGDPPGDPMGEW
VPHPEGLTYAEELVRLIRELGDFCVGVSAFPYGHPRSPDLETDTRYLLRKLDAGADFAIA
QLFFEAEDFLRLRDRVATGSDALVLPGIMPLTTPRTWRKTIELSGAMPPRWLADRLEPLS
DDPKAFRAEGLDVITELCERLLAEGVPELHFYTFNRSKATRELVDRLGLRSARTKPVLAA
QS
>A0A5R8WFR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. NamE2|TrEMBL
MSPPSLIDTHPNLSDAAPVALSYELFPPRSPAAAETLWNTIRELETTEPDYVSITYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIIGQLLDTGVRGILALRGDLPKD
GQTTDGSLRYAQDLIELIRRVEQRRSAMLCAGKIAVGVAAYPARHPESPSEAHDVEVLLA
KQRSGADFAITQVFFHADQYADLLTRARRAGVTIPIIPGVMPLTSLRRLNRLGELTGVEP
APELMSRLAAADSDLERLHIGVDATVDLANAALHAGAPGIHIYTFNEHQSALEVLDKLAL
PRHSRHSSRQHQGVQSQLAS
>A0A2R4TBG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lunaelactis|TrEMBL
MRTLRDVLAAGELSYSFEFFPPKNDTGEERLWDAVRRIESLSPAFVSVTYGAGGSSRDRT
VAVTKKIATQTTLRPVAHLTAVGHSVAELRHIIGQYADAGIRDVLALRGDPPGDPKGTWV
PHPQGLSYAAELVGLVRELGDFSVGVAAFPERHPRSPDWDSDIRHFAAKCRAGADYAITQ
MFFDVEYYLRLRDRAAAAGCHTPIIPEIMPATDYRQIRRFAELSDAAFPEELAGRLYAAR
DNPDEAHRIGVDHAITMAERLLDADAPGLHYITLNRSPATVEIHRGVRKTRSTHALSVRH
>A0A7W1FFT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRNFRELLGGDGIYVFDGAVGTRFYDKGVYINRSYDELNLTAPDLVREVHTEYVKAGADI
IETNTFGATHHRLLQYSLENKLREINVAGARLARHAAGENVFVAGAVGPLDLRIEPYGPT
SFDEAREMFKEQIAALLEGSVDLFVLETFSDLSEIQQAIKAVRELCDLPIVAQMTIATDG
KTIFGADTEILAGRLDEYGADVIGLNCGVGPTHILTALEKMRAVTTKKLAAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRFIKAGASFIGGCCGTTPQHIKLISDAVRAVSPRQSKAVKP
TTETVKVIDLKPVDVEIIPPEMRSKWSRKIALGEFVTSVEVLPPKGCDAAKTLESIKLLK
TAGVDAVNIPDGPRAQTRMSAQATAILVEREIGIEAVLHYCCRDRNLLGMMSDLLGAA
>A0A2V7U3Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MGETKAQASGVKPFLERLRDGVVVCDGAMGTMLYSRGVFVNRCFDELNLSNPGLVQGIHQ
EYVESGADVVETNTFGAHRFKLGPHGFEGQVVKINREGARIARAAAQGQALVAGSIGPLG
KPLEPFGNIAFDDAVAAYREQAQGLVEGGVDLFLLETMPSLDQARAAVTAVQTLSELPIV
VSLTFNEEGTTAYGEKPEDVVRTAEEWDVAVVGANCSQGPQQMLETVKRMAAAASRVKLS
AMPNAGAPALIDGRYVYLCTPEYMASYARRFIAAGVSVVGGCCGTTPPHIRNLVRSVRMG
QPAREVVTLEAPARAKEAPAPIPRDDKSPLARKLGKQFVVSVELDPPKGADPGRIIDRAQ
YCKENEIDAINVADGPRASARMSAQSLCVLLQNKVGIDTILHYTCRDRNLLGIQSDLLGA
YALGLRNILAITGDPPKLGDYPDATAVYDVDSIGLIRIMDHLNHGCDLAGNLIGPALGIH
IGCGADPSKPDWDKEIRRLEEKVKAGAEYVMTQPVYDPATVERFLSAVRHLQVPIMIGIL
PLYSHRNAEFLHNEVPGMRIPDDIRERMHKAGSGEKAQLEGVAIAQEALLAARELAQGTY
IMPPFNKVELAVRVIEPLG
>A0A7W0TN66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MLSEDSRSRLRRRFTEQIVVCDGAMGTMLHSTGVPLDRSLCELNVTQPRLVRDLHAAYVS
AGADIIQTNTFDANRLRLSRVGLEDSVVELNIAGARLAREAARDSDRTVLVAGSVGPANS
ATAVSRVPQRMRAEVLREQIAGLVDWVDLLMLETFGDLDSIVQAVEVALEETDLPIVAQM
TFGNDGATLRGEDPAGVLAVLDRLDLAALGANCTVGPAALQDVIAELAASSQLPISVQPN
AGTPQRLGRQVRYVHNTSYFAAAAAEFVGNGASIVGGCCGTTPAHTRAVAKAVAGLESTH
RPQPSPPVQPKPARTEPPVVENALAPPAWPQEAGFVVIAGLAAPQGPDVGDFVDQARELK
NAGATVLAITEPAPPAPRVGPVAAAVVLHERVDAEVLLPAETADRTLPALQADLLGAHAL
GLRMVVCRTGSPRIAGDYPDAAQPWDVDSVQLIAALRGLNDGQDWRGVATRERTHFVIGA
SISTTAADLDREVDRAEAKAHAGADFLVTDAIHDADEATLLLAALPARGIDIPVIASVAP
FEGFRALERLRNEVPETSIPPAIVRALPRAGAPPGDVIEASVELIEKLRGLISGVLVQVP
RSSQQSAVELLRRLAGLGERS
>A0A2V9M2C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MLKPFLEHLDKAFVICDGAMGTQLYSKGVFLNRCFDELNLSRAPLVREVHQEYLWAGAEI
LETNTFGANRIKLEPHGLADRVRDINISGVQIAQEVAQGSAYVGGSIGPLGIRLEPYGKL
GVEEARRIFAEQIAALVEGGVDLLCLETFTDLREIEAAILAAKELCDLPVMAQLTLEEDG
NSLDGTPPETFGPHLEKLGADIVGINCGVGPQVMLESIERMARVVTRKIAAQPNAGKPRN
FEGRNLYLSSPEYMASYAKRFVRAGVRVVGGCCGTTPAHIRAIRAAVVAAKSGASRIVAV
PAAEPTAPVEVTPVEERSHLGRLILAKKNITVVEMLPPRGVDATSALEAARHLKDAGVDT
LRISEAPRASARMGGIALAVLLERDAGVEPILHYTCSNRRLLAMQSELLGAYAIGIRNLL
LSDGEPIRVGDYMDATAVFDVDSAGVTRLAWGLNQGRDLGGKPIGKPAGFYVGVTVNPLS
LSTDEEIRRLEQKVEAGAEFVITEPIFVPDLLEAFIRRTQHCPVPVIAGIRLLTTARDTE
FLANEVPGVSVPDHVLNRMRAAGTPEREREEGIAIARELVRSMRGIAQGIDLSIWNLPYD
SALEVLAGS
>A0A2V7WKQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTFLADGRTAFGESADHALSTLAMAGADVVGMNCTLGPQETHDVFSRLPASIAAPLSVMP
NAGYPTVVHGRNVYLSSPDYLRGYAEAFVESGAAVIGGCCGTTPEHIRAMARAVSGKKRA
AATGRAAVRIEGPALKIGPPVIETSRLKRRLADRNAFVVTGEIEPPRGVDLSAAIEGARL
LKAHGADAANVTDNPMARLRMSSIAVAALIQREVGLDAVVQITTRDRNVLGLQSDLLGAA
GLGLKALLCLGGDPLKIGDYPQGKQVSEVDVLGLIRMAKGLNAGADLAGNAIGSATQFAI
GCAANPAASDLDVELSKLRAKIEAGASFAQTQPVYDAEALERFLACDEAQAIPVLIGLIP
LRSLKQTMFFANEVPGIVVPEAVQERMRRAAEKGTEHEKAEGLAIARELAVAIHQVARGV
HVMPMGKYKLATEILEAIPLESASSLRTRVSGA
>A0A7W0TMS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MSPPGEGRLRAALESGRFAVTAEIGPPRGADGDAIARKADLLRGWVDAANITDNQGSHTR
LASWAGSILAMRSGVEPVMQLTTRDRNRIALQSDLISAGAVGIPNVLMLSGDHPTFGDHP
DAMPVFDLDSVQLIWTARLMRDQGRLLSGKPVKPAPQWLIGAVENPFAPPLRFRAQRMGK
KIAAGAEFVQTQFVFDLDIFSRWMGEVTDLGLEQRCGVIAGVGPIQTVRGMEFMQTKVPG
IHIPDDVVRRLRSVPSDQVAAEGMSICVETMEALRETTGVAGVHVMAFGQEQVVPELLER
AGIPPRTANVLRT
>A0A7Y4SQT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKSFLEAIDERVLVCDGAMGTMLYAKGVFINQCFDALNLTAPGRVAEVHGEYVRAGADVI
ETNTFGANRIKLRGFGLADRLREINVEGARLARSAAGNHVYVAGAIGPLGIRIEPWGRTG
KDEAEAYFREQAEGLVAGGVDLFVLETFRDITELRAAIAAIRSICALPVVAQMTIEEDGN
SLDGTPPEQFTPELESYADVVGVNCSIGPAPMLETVERMAAVSRARLSAQPNAGRPRDVD
GRNIYLSSPEYMASYARRFMSRSVRLVGGCCGTTPEHIRQIKMAVKASMSDAPKSGRSAV
ASSPVVVRTPEASATVVPLAERSRLARALSEGRFATIVELRPPKGCVSDEVLAHARALKS
RGVDVVHIPDASRGARMSALSLAVLLQEHANVETVLQYSCRDRNLLNMQSDLLGAHAMGI
RNVMLVTGDVHTVADYPDATVVFDVDSVGLTNVVTRLNQGLDVGGQPIGRPTSFHVGVLV
NPAADDLDREIRRFEYKVEAGAEFAVTRPVFDPGLVERFLARVKATRLPIILGLWPFDSA
LNAEFMANEVPGTRVPEALLERMRRAEARSPEAAVEEGVVIAREIGRTLRGAVQGVHVAS
PSERIESVVEVLTGVSL
>A0A3M1SSZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRSFRSLLEDDGVHLFDGAIGTRLYEKGVYINRNYDEINLTAPELVLEIHEEYVRAGAEI
IETNTYGATRHKLQLFGLENKLREINIAAAQIARKAAGDKVFVAGAIGPLGLRIEPYGPT
SFDEAKDMFKEQAEALLEGGVDLFVIETFSDLSEIQQAIKAIKEVCDLPIVAQMTIQTDG
KTTFGADAKLIALRLEEYGADVVGLNCGVGPTHILSALEQMREVTDKKLSAQPNAGLPRD
IQGRQFYMCSPEYMSKFAKRFIKAGASFIGGCCGTTPKHIKMMCDVVRSLSPRVQKFYIK
RQETVRVEELTPPDVQVVPAEERSNWARKITRGEFVTSVEVLPPKGIDAGKTLESIKLLV
DAGVDAVNIPDGPRAQTRMSALATAVLVQQKVGIEAVLHYCCRDRNLLGMMSDLLGAAAL
GVNNLLIITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGKPTRFSIGV
GVNPGAINIDEEIRRFEWKVEAGAEYAITQPVYDTKQLRDFLKRIEHCRIPIIAGIFPLV
SYRNAEFMHNEVPGVNVTPEILERMRKASAISKEAAREEGLRIARESLLEIRDLIQGVQV
SAPFGNVKYALQVFEVLDEFKDRQKQAQTL
>A0A7Y2TQ63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MTAPRISFEFFPPRTEEQQLVLESTWQKLAPLRPEYLSVTFGAGGSTLEATRETVAALSA
STDVPVAPHLSCMANSKAMLRDILVAYRDMGVDRLVVLRGDRPEGQSGPGPFQYANQLVE
FVRGEFGDHFHIEVACYPEFHPESESAETEMFYFKQKVDAGADGAVTQYFYNADAYFSFV
DESRRQGIDIPITPGIMPITNYRQLSRFSAMCGAEIPQWIRRRLEAYGDDGASIRAFGLD
VVTALCERL
>A0A7K9AYJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dromaius novaehollandiae|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDK
WFSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVN
YCGLETILHMTCCNQTKDEITGHLQRAKRLGLKNIMALRGDPAGEEWEEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRIGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKDQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A4E0PT92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanolobus halotolerans|TrEMBL
MSQTFKNKLISDDFLITAEVSPPKGTDLSESIADADIIRNWADALNVTDNQRAVMRMSPV
AVSKNLLDAGHEVIMQLTCRDRNRLALQSELLGAFALGVRNMCVMTGDHTTKGDHPGARP
VYDMDSVQLLDIIRRMKEGHDLAGNVIDKPPAFTVGAVTNTDPSKNMQMMKLRKKSKMGL
DFIQTQAVYDIGQFEAFMEAIGDIEVPVIAGLIPLKSAKMAHFMNENVPGINVPAEVTQR
MANAEKPIEEGISICSEAINELKELCRGIHIMPIGKHVNTPKILEIAGIRKKNND
>A0A2V8DRK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MAKSFLEALDDRVLVCDGAMGTMLYAKGVFINKSFDALNLTRPDLVGQVHEEYVRAGADI
IETNTFAANRIKLGWFGLADKLHAINREGALIARDAAGDHAFVAGSIGPLGIRIEPWGKT
GVDEAREYFREQGQALIEGGVDVVIFETFRDVNEIGAALDAVRSISDLPIVAQMTTEEDG
NTLDGTPPERFAPELERRGATLIGVNCAVGPAPMLETIERMAAVTRLRLSAQPNAGKPRD
VEGRNIYLCSPEYMASYARRFILHNVRVVGGCCGTTPEHIRQIKLAVRALAPAAARPSTM
LGADRVEQPAAPRPAVAISAPPVPRERKSRLAHAMASGTFVVAVELLPPRGFQCEPAIER
ARSLKIRGVDVVPIPDGQRAGARTSALSLAVLIEQQAGIETLLHYSCRDRNLLGIQSDLL
GAHAMGLRNLLLITGDPGRVGDYPDATAVFDVDSIGLTNLVARLNRGCDVGGQPIGAPTG
FHIGVSVNTAASNIDEELRRFEYKLEAGAEFVVTRPVFDLRCFEQVLKRLEPSKLPVVAG
LFPFESARNAEFMANEVPGVRVPEALLDRMRAADGTEAAIHEGITIAREIAAQLRSSVQG
IQVSTGSGNIDAALAVVDGLR
>A0A7Y2XGD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MSRFQQAIRSGRLALSAELLPDPGREPGRELERARRLADRFDAVIVNPAAGEPATPPPAA
MAALLLREGIDPVCVLNCRDRNRIALYSELLGLRAAGVRSVVLERGEDTGLPKHAKPVYD
VDVRELSAIAQELNEDEAAPGQEFLVGARLPLIDPAADWNDQPLAALASAGTEVLLTRPC
QDQKRTRDMMARFVAERLTWRFSVVVTLAVPVSSEEARRLADSVPGSRVPASLFEELDTA
ADPRTEGIGLGARLIRETAELPGVSGINLLCLDEVEPLLSAVAGAGIQSSS
>A0A8G0TWL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella putrefaciens|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAADLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPNWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A7V0UD32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRLPNPLRESLTGGKFCHVVELVASRISREARHLDTAAQLARIPGVVAGSITSYAGGSPG
HDPIRVGTAARARGLTPNIHLTCVSRNRSELRRALEDLHALDIENVFALTGDYPQGAPSV
FDLDSVALVSLIQEMRQGGMPFWIAVAVSPFKYTEPDCVYQYIKLEKKFAAGADWAITQV
GWDVRKLRELQQYLRERGIQKPILGNVYVLNKRAAEKMAKSEPPGCWVSQELLERVQAES
KAADGGEAARLERAARMVAVLRGLGYAGAYIGGTHKAEHIRWIIKRGEALAPKWEEYAEE
LTYGMKGGFYMYESTPSPPQPLKGRARVIDYLGRTFTPTVVPKGSSLQRLFTRFFGWIDR
RPFLARSLERAEVALKAPMFGCKSCGNCVLIHMENVCPQTCPKQIRNGPCGGTNNGQCEV
IPDQKCIWVGVYERAKAANELEQLKVYIPPPDRSLQGTSAWINYFLNRDSRPEKPAPPPA
AQERPLSHQKSSVG
>A0A2V8NHL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MENFRNILEGDDVQVFDGAVGTMLYAKGVYINRSYDELNLTNPELVRNVHEEYMRAGADI
IETNTFGATAHKLQQYGLEGSLRLINIAAARIAREAAGERCYVAGAVGPLGLRIEPYGPT
SFDEAKEMFKDQIAALLEGGVDLFVLETFSDISQLRQAILAVQELCDLPIVAQMTIMPDG
NTTFGTTPEVFTTRLDEWGADVIGLNCGVGPAIVLNAIEKMRVVTNKKLSAQPNAGLPRD
VQGRQFYMCSPEYMAKFAKRLIQAGAKFIGGCCGTTPAHIKLIADAVQAASPRKQRIVIK
EAAAARVEELTPADIQVVPPEERSLWSRKITNGEFVTSVEVLPPKGCDPMKTLDSIRLLK
DAGVDGVNIPDGPRAQTRMGAQATAVLVEREIGIEAVLHYCCRDRNLLGMMSDILGAAAL
GIRNLLLITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGQPTAFCIGV
GCNPGAINLDEEIKRFEWKVEAGAQYAITQPVFDTDQLREFLERIEHVRVPIVAGIWPLV
SFRNAEFLHNEVPGVRVTPSIMERMRIASEKSKEAARDEGLKIARESLLEVRDLIQGVQV
SAPFGNVRYALEVFDVLDEFAARKELNVTV
>W0I0W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermococcus paralvinellae|TrEMBL
MVELRIFGCPKSLLNGPCGGAFNGKCEVNENHCPWLGVLERVHYLDGAVLFNEHPILMEI
EKIPSRDVKPKNSNFWSQVEKGKALSVEFPIAAVRDEVEIARVIAKTNSDLYTIPDNPLG
CPHFSSTAFATHLKHFGIEVMPHLTAKDRNLTALTAELKTAVLFNFEVVLLTTGDWPSLA
LPSRPVFDLDSANMIRLARLIFNGVLPTKETFEVEERPRVAGAMNPHYRPRVEAQRIARK
LIAGAELFFTQVVATKESVTRIKETFIELKKYINAEVPVMVSLLYPISDDIKPLLRKMGT
QTGDDTFEEVLEEVKALDVAGGVNLIILSRNLDVWLKPLERSV
>A0A1F4FHJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_65_14|TrEMBL
MLVMRRWAVRHAGLVERAYQALAAVLRALRPLARAIGFARLQKPMAGIERAIKGFLFDCS
MCGRCALSVSGMSCPMNCPKGVRNGPCGGVRADGSCESSPGMRCVWAEGWRGSLRMSAGQ
LPLAASPPAEWNLAGRSTWLDVIAAEAPLPRFVIDAPPQPSGSRLEAQMESGAFVVTAEF
SPPDSADPADVLARIAPFRGSVDALNVTDASGANCHMSSLSVAVLLTQAGGEAVMQVSCR
DRNRIAIQGDLLGAAALGVRNVLCLTGDHVTNGDQPGAKHVGDLDAISLLATARSMRDAG
RLLSGRKLAVAPRLFLGAADTPSAPPFDARIARLRRKLAAGAQFIQTQYCFDVPEFERYM
RAVCDAGLHERLRILVGVGPIGSAKTARWLRARVPGVHIPEAIVKRLEHAADPREEGRRI
CIEIVRQLRELPGIAGVHIMAPKQDHLIPSIVAESGILAGRTPLFGARQPRAALA
>A0A374EB08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM33-14|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPD
AMKQAGIAYATDQIIDLLANGVNNIHIYSMNKPEIAVAIMNNLSEIIKC
>E1M8U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus infantis SK1302|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQNMQDLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFIKEQVPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAQYIHQATHALFNHQSLG
>A0A1I3L6R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olleya namhaensis|TrEMBL
MKVTEHISRGEGKTQFSFEILPPLKGQHIQKIFDNIDPLMAFNPPFIDVTYHREEYVYKD
LGDGLLKKQVVKKRPGTVGICAAIQNKYNVDAIPHILCGGFTKEDTENFLIDLDFLNIDN
VMALRGDAVKTETYFTPEKEGHAYASDLVKQIAALNKANYLDDQLLNCSATDFCVGVGAY
PEKHMEAPSLDSDIHFLKKKIKNGAEYVVTQMFFDNEKYFQFVDKCRSEGITVPIIPGLK
PISTLKQLNVIPHRFHVDLPEALIKSIIKCKTNVEVRQVGIEWCIQQSLELKKAGLPMLH
YYSMGKSDNIKAIAEAVF
>A0A2V8U9Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MQIKDFLARGRPTFSFEFFPPRTEEAARQLEQTIAQLRELKPTFVSVTYGAGGSTRDRTI
EIVSRVKREAGIEAMAHLTCVGSRREDLAAVLERIGEAGIENVLALRGDPPKGQTEFKAV
EGGFRFASELVRFIRDRHNSALCLGGACYPEKHPECGNPAVDLMNLKRKVDEGLDFVVTQ
LFFNNRHYFEFVERARRAGIKVPIVAGIMPITNASQIERFMVGCGATIPFELAEELDRRR
DDPNAVMELGIAHATAQCIDLLKQGAPGIHFYTLNRSTATREIYAALQSAGFTPS
>A0A5M3VV20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acrocarpospora corrugata|TrEMBL
MSLGLPSRFPDRVPTVKDLLAAGERSFSFEFMPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGGTRDRTVDIVERIAHGTTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVR
GDPPGDPMGTWVRHPEGVLYAEELVRLIRQSGEFCVGVAAFPYKHPRSATIESDTEQFVR
KCRAGADYAITQMFFKADDYLRLRDRVAAKGCDTPIIPGIMPVTQISTIARSEQLSGAPF
PPEVAARFEAVAHDPESVRRLGIEHAAELCQTLLDEGAPGIHFITFNRSSATREVFQALT
PAVVV
>A0A399Y7G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MDRLRAPRGARIPFSVEFSPPRDADAEARLWRAVREFERLGPAFVSMTYGAGGSTRDRTV
RVTGQLAQETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWTR
HPQGLEYAEELVRLVRDLGDFHVGVASFPEAHHRSPDLEHDTRYLVHKLRAGAEYSITQM
FFDVEDYLRLRDRVVAYDPEQGAKPIIPEIMPITSLRTARRSLELSGSKLPATLEERLVR
AAGNGPEEDRAAVREVGIDVATEMAERLIAEGAPCLHFITLNFARATREVLARLGIAVPT
AV
>A0A2V8VRR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTRPIAPVLRLEEAFRSGLPVVTCEIATGDGADPDEVLRRVRLVSDHVDAVNVPDNTAGI
VHMAAWAAAALLAREGVDPIMHVTCRDRNRMALQSDLLGAAALGVRNILCLTGDHMVHGD
HPGAKPVFDLDSLQLVSLATVLRHGRYLSGREIRPAPALFPGATENPFAPPYDFRPLRLQ
KKVEAGARFIQTQITFNVKRFAAFMERVRDLGLDRTVPILAGVAPVRSARSARYMRERVP
GMEVPDAIVRRMEQAGSERARREDEGIRVCVEIIEQLREVRGLAGFHLLPIHWEEAVAEI
ASRARLTPARASLSAHVEATARDAGSADARRDDREGALLNRHREHRA
>A0A1C4ZUJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora echinospora|TrEMBL
MPDVLATARQRPLLLFGLTPPRRSATPEQAAEIARVTLARLAPLDVDALLLYDIDDESDR
NPDERPFPYLPTMDPAVFHATHLGNWHRPTIVYRCVGKYPEPELRDWLESTDPDRVAAVF
VGASSSTKEVHTPLPRAHALRREVRPDLAVGGVAIPERHSRGRDEHLRMLAKQEHGCAFF
VSQVIYDVDATKSLVSDYRYACRERGVAPQPIVFTLSVCGSLKTLSFLKWLGVAVPWWLE
NALRHAEDPLAESYEQCLANARELAGFCRRLGVPFGFHVESVSIRKVEIDAAVTLAARMR
ELLTD
>A0A0W0MXH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ICMP 19500|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0R1Z4R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus parabuchneri DSM 5707 = NBRC 107865|TrEMBL
MSLTELFKHKTVFSLEVFPPKKTSPTEAILPTLTRLQSLNPDFISVTLGAGGTDHCDGTV
EIANLIQNKLNIPAVSHVPGLYQTKEQVLALLDRLDSINVKNILALRGDRIAGKQPAGDF
THANELVKFVKEQRPDFTVASACYPNCHTEAAGFVDDLAHLKEKVDAGADHLISQLFFDN
QAFYDFKEKTEIAGINVPIEAGIMPCTNKNQIERITQISGVPIPKKFAAIMDRYQDSKEA
MLDAGIAFAVDQIIDLVSQGVDGIHLYTMNNSKIAKRIWDETESVFAASDLSKQKANS
>A0A523DJM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRLIRDIYADKQAMGLPVISVEFFPPKTPKGDETLFERTLPALQAVAPDFYSVTYGAGGS
TRDKTLAVVDRIQREHRTTTMAHLTCISTSRADIEHYLLEARAKGIRNVLALRGDLPQDS
GDLAQVECGFEYSYQLVAFIKQMGGFSIGTAGFPESHVACTDGKQVDWQRLKAKIDHGAD
VVLTQLFFDNDDYFTFRDYLVETLGVRVPITPGILPILNTEQIKRFTEICGSTLPAPLLA
KLEAFGDDAEAVTEFGIEFATRQCEALLAGGAPGLHLYSLNKAHAATRIIDNLGLRSTRS
PTPRA
>A0A1W1XQF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium acidisoli DSM 12555|TrEMBL
MCIYLLYLSLKRMLRQKILDKRPGIITYGITPPKKDTEIEKVKQISQKQIERISSIDIDG
LILYDIQDEEDRIKAERPFPFLETIDPQIYSEEYLNDLKISKIIYRCVGKYSEEEFDNWI
NIDSGEDRFSVFVGASAKTQKVRLNLPKAYELTKNLNPDLIIGGVMIPERHTKHNDEHLR
IINKIRNGCKFFVSQAVYNIESAKNFLSDYYYYCKSNEIEMVPIIINLTPCGSIKTLEFM
KWLGINIPKWLENDLMNSEDILHKSLELCKKTFEELLDFGLQKGIPIGCSIESVSTRKVE
IEASIELTRDIKAMIDKRLKKTFS
>A0A378VWB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae|TrEMBL
MNYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGMMHPTTKLRQIAKDYWDSGIRRIVALRGDEP
AGYEKNRFTPKTWLSYYAPSPTSTSL
>A0A134DIW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hominis|TrEMBL
MSLAAGTAPRVAGCPKSMAYGPCGGVNPDGTCEVDPTPCVFLRRDLPVRWDGNGDAPVDR
DPVDAVTTAARGEVAEIAQRRPLVFTGFPVRALRSDAVRPTADALSGSVDAVLSGDAGRS
RVQFPPSYRAALIAATGLRLWMGFNARDRNRTALERELLSLRALGVAGVHCVTGDHTQTG
DRADARPVFDLESTTMLPRARALGLLTSFAESPAAPPVAERGARVAQKQRAGGRLCLTQY
AGDAEEVADFVTQCRTAGATAPVLPGVPLVIDRDGAGLLASFHAAKLPRGFIDRLFAARD
VRTEGIRLAVEYGRALLDTGLVGGVVIAGGARLGEEVSYAADLATVARELGGGT
>A0A2I0CEB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas hunanensis|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3R7SR32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium TMED51|TrEMBL
MSTLSNALHSSEFVVTSELTPPKGLDLAPLLEKAGLLKPYVSAINLTESHAARMAMDPVA
VGHLMLDEGVEPIVQMTSRDKNRLAIQASILGACALGISNLVFMGGDSPKNGDHPDAKPV
FDLFASQLLEAVRALNNGADLNGNTLNQHTEIFAGAVVNPGATDPDAEIENLHRKINGGA
EFFQTQAVYDVNAFSAFLEKANSPKPILAGIIPIKSVKMAQYMNERIPGVDIPNHLIEKI
AAAGEDKDEIARISIEIAADTIRELRSVTKGIHVMAIGWEQHIPTMLEQSQS
>A0A068VTW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium freudenreichii subsp. freudenreichii|TrEMBL
MLDNYRPADLAPARRSNTDTTQTIAELLARAERPTFSVEFFPPKTDEGARVLHEAIEKLE
PWNPDFVSVTYGANGSLRDRTLAAVRDMVASTKLRVVGHLTCTGQSVDELKSVIDAYGDL
GVHHILAVRGDMPGGPRQPWEPHPQGLKNATELVELVKSRGDYCVGVGAFPDIHPGSTPE
QDVRVLHDKQDAGAEFAITQLFFRPSAYYDLIDRMRADGCTLPVIAGMMPVTAISQLDKF
AELSGVPLPASVTERLMAVANDPLAVRATGAQICAELASDLLERGAPGLQFFTRNRSAAT
REILAILLARRPW
>A0A1H6F1B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea solani|TrEMBL
MIMSFELICEIEPPTTPDLKHVRHQIGTMSKIAHSFLIPDNHIGRATVSSVAVAHEVEAM
GGRGIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVFGDKPSSGNRTSDLTVRSMIEEAR
AFTPGVRLGAAAGLRPLPSWKRAADFLFSQVSFSVEAQLRWRDEHPVDVPVYAGVMVLAS
ANHARTLSAAIPDIALPDDLVARVAADRMAGVEAACEQVLALRDSGAFAGVHLIPVSRYR
DIEPRLAAALR
>A0A6S6YCY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denitratisoma oestradiolicum|TrEMBL
MSKPELSIEFFPPQTPEGAIKLRDARARLAELKPAFFSVTFGAGGSTQERTLDVVLEIQQ
EGHQAAPHLSCVGSTKSKIRDILHRYQAAGIRRIVALRGDLPSGMAHPGELRYANELVEF
IRQETGDCFQIEVAAYPEWHPQARSAQDDLKNFKRKVEAGANAAITQFFYNADAYEHFVN
EVRALGITIPIVPGIMPIGSFSKLSRFADACGAEIPRWMRRKFEGYGDDAESIRAFGLDV
VTELCQRLLDRGAPGLHFYSLNQSELTTEIVRRLRI
>A0A7R9YL55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diacronema lutheri|TrEMBL
NIVALRGAPPKGQEKWEAVAGGFSCALDLVKYTRQQFGDWFGIQVSGYPEGHPDVIKPVA
ELGRPLSASEQKRLVTVGSGASAEQFVCSDADFDRELGYLKQKCDAGADCVITQMFFDFE
VFEAFVTQARAKGISAPILPGIMLITAYGGFTRMTGFCKSRVPAELVAKAEALKEDAEGF
KEMGLSWTVALCKQLVASQLVPGLHFYTLNQSANTQQILQRLGLLLEQPTEALDEGDTLK
GTHIA
>A0A369QBX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteripontixanthobacter maritimus|TrEMBL
MTQATPSAGRTVAPRFSEEQPLFAGLPGDIAMSFEFFPPKSEKMAEKLWDAVQELRPLAP
EFVSVTYGAGGSTRERTHNTVARIIAEAGIPAAAHLTCVDASKAETQAVAEQYWEAGVRH
IVALRGDAGEPGAPFKPHPEGYDSAADLVRGLKEVADFEISVAAYPETHPDADCPQSDLD
NLKRKIDAGATRGITQFFFSADTFFDFQNRVKDAGIEAPMVPGILPVTNVAQARKFAGQC
GAVIPEWMDGLFEGLDERPAARQLVAATLAAELCRRLYAGGVRDFHFYTLNRADLAYAIC
HMLGRRPVGELS
>A0A0Q7HMA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Root1295|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVRA
TQQIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A7C5LXT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliiroseovarius sp|TrEMBL
MSAPESAPRSAPRLSFEFFPPQNLDASFRLWDTVRTLAPLDPSFVSVTYGAGGTTRTLTH
EAVATIHKRYGLNVAAHLTCVDATRAETLEIARSYKEVGVREIVALRGDPPKGAGRFTPH
PEGFANSLELIEALADEGGFHIRVGAYPDPHPESTSMAQNVEWLKRKVDAGAGSAITQFF
FEADTFFRFRDACDAAGIDVPIIPGLLPIENWKGVRKFAARCGAHVPGWLDDAFDKAARD
GREDLLAVALATELASDLIEGGVRDLHFYTLNKPGLTRDIAHALGVTARGDLRDVA
>A0A192TDP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium phaseoli|TrEMBL
MALKNEAQARNIGISFEFFPPKSEEMEGQLWNTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRRAGISIPIVPGIMPIQNLTQLKRFAGACGAVIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIRDFHLYTMNRSPLVSAVLDNLGLSRRPAKNAGAAA
>A0A5J6MYK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypericibacter adhaerens|TrEMBL
MIGAPTHISDRIKVSFEFFPPKTRENEGALWHTIERLSALQPDFVSVTYGAGGSTQDRTL
ATLRRLAQRTDLAVAGHLTCVGKTRAEVDEVARDYAAAGIARIVALRGDPPVQDGRYQPH
PDGYRDAADLVAGLMRIEDFDISVAAYPEGHPESASLEADLDNLKRKLDAGARRAITQFF
FEPETYLRFMDRARAAGITAPIVPGILPVTNFKTVQEFARRCGASIPGWLARTFEGLDED
PATRELIAATVAVDLCLKLRAQGVTDFHIYTLNRAELTLAICHMLGLRSGAARRRHRCQG
EETASQTASTSA
>A0A6I5WZM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. Gsoil 351|TrEMBL
MTRLAPRPGPEPGAASEPSFAHLPGDIAVSFEFFPPKSEKMEQQLWDAITQLAPLNPSFV
SVTYGAGGSTRERTHATVARIVQETALVPAAHLTCVAASKAEIGDIAEQYWDAGVRHIVA
LRGDPPPGEGARFTPHPDGYSSAAELVAGLKARRDFELSVAAYPEVHPDAATAAADLDNL
KRKLDAGATRAITQFFFSADAYFRFLDQTLAAGITAPIVPGIMPVTSFSAIRRMSGNTTI
PASLEALFEGLDERPGPRALVAAVAAADLCRQLYAGGVRDFHFYTLNRAEQAYAICQLLG
LRPEPTP
>G8F4Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macaca fascicularis|TrEMBL
MCRGCGCLPPDAPCPTLCSRNLAMVNEARGNDSLNPCLEGSASSSSESSKDSSRCSTPGL
DPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHP
AGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALR
GDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPKGHPEAGSFEADLKHLKEK
VSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVP
QEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLG
MWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAF
GELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND
EPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFT
SRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDP
ISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVE
DALELLNRPTQNERETEAP
>A0A6G7EMG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas mediterranea|TrEMBL
MAASSTNLAEARALLLSPLGPVARAGSNHDAVRVSFEFFPPKTDEAEANLWTAIRRLEPL
NPAFVSVTYGAGGSTRERTHRTVQRIIAETSLRPAAHLTCVEASRDEVDEVIAGYKTIGV
DHIVALRGDPPGGGGIGGVYQPRADGYANATELTAAISRVGGFDVTVGAYPEKHPESPSI
DHDIDVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLTR
MCGACGTSIPDWLKAHFDGLDDDPETRRLLAASVAAETCARLHEEGFSDFHFYTLNRADL
VYAICRVLGVREQKAAA
>A0A5N7WEN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARRPEFCSVTYGAGGSTQAGTFTMVRDIQNE
GVGAASHFSCIGATHEKVRAELNELKAMGVKRIVALRGDLPSGYGLGGEFQYASDLVAFV
RQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VRALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A2P8QKK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroococcidiopsis sp. CCALA 051|TrEMBL
MTEQYITDRDSRNSFRTAVKSGEFLITAEVTPPKGSDPTRMIEVALALKNWVHAVNVTDG
SRAVLRMSPLAAATILLQHGIEPICQMTCRDRNQIAIQADLMGANALGINNILALTGDPV
KAGDHAQARSVFDLEAVRLLQTITKLNQGFDYNGKTLCDGATQIFPGAAVDPQLASWSGL
QRRFERKVAAGAQFFQSQMIVDFSRLEKFMSQIAAKFNKPILAGIFLLKSAKNAQFINQY
VPGVNIPQAIIARLEQATDPLHEGIVIAAEQVRLARQVCQGVHIMAVKREDLIPQILEMA
EISPQGQSVQNVATTKIALAEPLLRRNSHNINNFHTRL
>A0A1C0S7P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. LC14|TrEMBL
MSPDINPFDPGAPLEPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGVG
PMASAKTARWIRSNVPGIHIPDSVVARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGIHV
MAYRQEEYVAEIVHESGVLKGRKPWKHETLPEDAMVAERLEHIREGKEENQQQMAEAAAH
HPH
>A0A0M6VW88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limosilactobacillus vaginalis|TrEMBL
MTTLSYEVFPPNSTVGINHLNQVLTSLRDLSPDFISVTCNSNTKQLAHETVRVADYVEND
CQVPAMAHLPAWYLSREDVDRILEQLRVCHVDRVLVLRGDERPKLEKKTDFAHASDLIAY
IKQNYPDFQITGACYPEKHPESLSMVDEIQHLKLKVESGCDQIITQLFLDNHSYYRFREL
CAIGGIDVPIIAGIMPVVNERQANRILRTSAVTVPEKFKDILAKYHDHPQALKQAGITYA
IDQIVDLVTNDVSGIHLYTMNHSDTARQVKQNIGSLFRVCC
>A0A2D0IUZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus ehlersii|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERDRTHSIIKDIKEKTGLDAAPHLTCIDASRAELSNIAHDYWQNGIRHIVALRGD
LPANGCKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFASMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A144M917|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium linens|TrEMBL
MSQSTLRRLLSTARYEVLPTAGIVERVEEYVAPGREITVTASTGLTLEATLSTAEQLQAL
GFRAVPHLAARMIHGRPELTEIVDRLAEAAVDRIFVPAGDATPPAGGYVGAHDLLVDLSS
MAAPFQHIGVSAYPESHPIIPDDVTIQAMWDKRDYATHLVSNLCFDPALVASWVARVRSR
GIELPLVLGIAGKVELAKLARVATKIGVGESTRFLRKNTATFTRMAKPGGYNPRKFLDKL
GPVLDDPDMGVAGLHIYTFNQIKDTEVWRRKQLAALGGAEEVSNLT
>A0A069JRT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NTK 937|TrEMBL
MRELLATGKTSYSFEFWAPKTAKGERNLWNALRRVEAVRPSFVSVTYGAGGSTREGTVRA
TQQIAADSTLTPVAHLTAVDHSVAQLRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSDDWDSDIRHFVDKCRAGADYAITQMFF
HPESYLRMRDRVVAAGCDTPVIPEVMPITSIRQLERFAQLSNASLPSSLKERLLAAKDDP
AAVRSIGIEFATEFCAELVSEGVPGLHFITLNNSTATLEIYENLGLHRQS
>A0A502KJM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus haemolyticus|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWESGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPS
>A0A494RZP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium xerosis|TrEMBL
MSDFPPPAVGRQVPVRHALTLPSPGPVPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFA
SVTYGAGGSSRDRTLRIAERVSREPLTTLVHLTLVGHTVPELREILRAYLDRGLTNLLVL
RGDPPGDPLGDWTPMEDGLSYASELIEFIRSEEEFADFEIGIASFPQGHFRAPDLESDTR
YTLAKLRAGAEYSITQMFFDVDHYLRLRDRLAAADPEHGSKPIIPGLMPITSMRSVRRQL
ELSGSVLPPALDERLTRAAAGDEEANRDEIRKVGIEVTTEMAERLISEGVPGIHFMTLNF
ARAAQEVLHNLGMAPAWGTGQDMLRGGF
>A0A200HQD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus cecorum|TrEMBL
MHPDSKNRVEDILNLKRKVESGCQQLITQLFFDNDTFYRFQESCALSGINVPILAGIMPI
INRKQAIRLIQTCQTKVPRKFMAILEKYEYQPESLKEAGLAYALDQIVDLVTQDADGIHL
YTMNQADTTRYIYQATTAIFQNLSHAS
>S4GXG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis JCP7719|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNAAGVFNHASDL
VSYIRSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A3B8HKL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacteraceae bacterium|TrEMBL
MSLREKLASGEFVVLAEMEPPKGVDVSAMVAHAARVKNRVDAFVVPEMSNAVMRMSSLGG
CMVLAGKGLETVLQVCCRDRNRLALQADLLAAHALGIANIMAVTGDDPSFGDHHRTRGVY
DIDLLELLEGIQKLEGGRDMAGVELKGAPSFCVGSTVNAGASGGMLDLELQQLDKKIAAG
ATFFMTPPVFDLQTLGRFAKRLGDRPCRILPTVLLLKSAGMASYIDRHLDNVHVPSDIIR
RIQKAGDKIRECVQIARELVMGLRDAGYGGALIATIGWEDKLPSIVEG
>A0A3D0X6G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp|TrEMBL
MGIGEQAKTIFSFEVFPPKRDMPLDSIYEALGELSDLKPDFISVTCGAGGSASGGSSRTI
EVTSAIQDKYGREGVVHLPCIYFAKDEVIETLKQMEEKGIKKLLALRGDRVPGEEPKQDF
RYARDLVAFVREQVGDRIQIFAACYPEGHVEAPDLKTDIAYLKEKVDAGVDRLISQLFFN
NDYFYEFREKTAAAGINVPIEAGIMPVTSKKQIERMVTLCGATLPRKFQRVLAKYEAQPE
ALRDAGIAFAIDQIVDLLGHGVDGIHLYTMNNPYIARKISESVRSLL
>A0A2E2QAQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micavibrio sp|TrEMBL
MIMDFNVKFSAEFFPPRDPNDDDALLAEVKKIAVYKPRYLSVTYGPAGLWADRTAGLARR
ICEETGIETAAHMTCIGQTKDALFEQLDMYAAQGIKHIVALRGDIPRDKEKPAPDNTDYF
HYANEFVEGIKAHNSDFDISVGAYPETHRDAVCAAEDLRFLKQKIDAGARRAVTQFFFET
DVFAQFLEQARAAGIDCEIVAGLSAINDFERICRYAKGAKAHMPDALIKQFADQQEDHLS
LAAVFLENQIKSLMQGGTRHFHFYTLNTAEPLLTALERL
>A0A7W4CYB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus sp. MC1627|TrEMBL
MPVTETSLRSVGELIRSAHGPLYSFEFFPPRSEEEEPVLWAAVGALAPLEPSFVSVTYGA
NGSRRDRTIRATRRIAASGGPLTVGHLTCVAQSKAELAEALAEYREAGVTNILAIRGDMP
GGGPWTAHPDGLANATELVKFVKAEGDFCVGVAAFANPHETSNDPDLDAQILLDKVEAGA
EFAITQLFFEGERYGELVERMRGLGCEVPIIPGIMPLTVLSQIERFADLSGRELPASLVA
ELGACSSKEEVREAGLAAAVRLCRGLLDAGAPGLQFFTQNRSKATREVLAELKGATPAP
>A0A7J6EC32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cannabis sativa|TrEMBL
MKVIDKIRCEANNDNVVFSFEFFPPKTEEGVENLFERMERMVAHNPAFCDITWGAGGSTA
DLTLDIANRMQNTVCVESMMHLTCTNMPLDKIDHALSTIKSNGLQNVLALRGDPPHGQDK
FVQIQGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDAIGPDGLASPEAYQVDLAYLK
SKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFIRMTGFCKTR
IPSEVTAALEPIKDNDEAVRAYGIHLGTEMCKKILGSGIKTLHLYTLNMEKSALAILTNL
GLIEERKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTTGWDQYPQGRWGDSRNP
AYGALTDYQFMRPRSRDKKLVEEWSIPLKSVEDIHEQFKKLCLGKLKSSPWSELDGLQPE
TKIINEQLVKINGKGFLTVNSQPAVNGERSDSPVVGWGGPGGYVYQKAYLEFFCTKDLLD
ALVEKCSRGFSSFTYMAVNKQGHWLANVDQTFVNAVTWGVFPGKEIIQPTVVDPASFTVW
KDEAFEIWSRGWARLYPEVDPSRKVLEEVENSYFLVSLVDNDYIHGDLFAMSFGTSSPAA
IQKYGAVTVTADPKPISGDSIQSL
>A0A2T3GQH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. SEMIA4064|TrEMBL
MSSKTENGQRGIRISFEFFPPKSEEAETQLWNTVADLSEWEPDFVSVTYGAGGSTKAPTL
SAVRRMIHETPFTTASHLTCVGATREDTHRVIDDLLSTGVRRFVALRGDPPGGVGAAYQP
HPGGYANAAELVSALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGANRALTQF
FFDNDAFERYHDRVRAAGIKIPVVPGIMPIQNLTQLKRFAGACGTLIPSWLDERFDGLDE
DADKRADVAADVAAEQIEDLVRRGIHEFHLYTMNRSPLVSAVLDRLGIPRKTDARAGAAA
>A0A1Q7YCM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_20CM_3_53_8|TrEMBL
MEDIRNIIESDEVLVFDGAMGTMLYSKGVYINRSYDELNLTSPDLVREVHSEYVRAGADI
LETNTYGASAHKLQQYGLEGSLRLINVAAARLAREAAGEHAYVAGAIGPLGLRIEPYGPT
SFEEAKEMFKEQAGALLEGGVDLFILETFSDISQMRQAIRAVQELCDLPIIAQMTIHTDG
NTSFGTTPEVFTARLDEWGADVIGLNCGVGPAIVLSAIEKMRNATRKKLSAQPNAGLPRD
VQGRQFYMCSPEYMAKYAKRLIQSGAKFIGGCCGTTPAHIKLLSDAVRASSPRKQKNIFP
TSTAARTGELAPSDIQVVPPEERSNWSRKITRGEFVTTVEVLPPKGCDAAKTLDAIRLLK
EAGVDGVNIPDGPRAQSRMSAQATAVLVEREIGIESVLHYCCRDRNLLGMMSDLLGAAAL
GLRNLLLITGDPPKMGPYPESTAVFDIDSIGLTNMVNKLNHGLDLGNNPIGKPTSFCIGV
GVNPGAINMDEEIKRFEYKVEAGAQYAITQPVFDTEQLRDFLHRIEHVKIPIVAGIWPLV
SYRNAEFLHNEVPGVRVTPSIMERMRKASEQGKEAGREEGLQIARELLIDVRDLIQGVQV
SAPFNNVRYALDVFSALDEFAGQKEGESKKVKGKRDKDEESAITASL
>A0A6C6ZUN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella dublin (strain CT_02021853)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0F7Y037|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CCOS 191|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALLAEYQAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGNHFHLEVAAYPEMHPQARNFESDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0A8K213|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloceanibacter caenitepidi|TrEMBL
MSATQDTQGQQPPKRRFLGRGDIEVSFEFFPPKNQAMEETLWRAIRRLEPLRPKYVSVTY
GAGGSTRERTHATVARILSETTLIPAAHLTCVNATKEEVDEIIRDYWDLGVRNLVALRGD
PPEGVGERYVPTPGGYENAAALVAGIKSIAPFVTSVACYPEKHPESPSVEADIDMLKAKV
DAGADGAITQFFFDNEVYFRYLDRVRAAGIDIPIIPGLIPINNFKQAASFAKRSGASVPD
WVERRFEGLEEDSETRHLVAAAVAAEQVLGLVDQGITSFHFYTLNRADLVYATCHLLGLR
PAKAFSQKADEASEPAKIAKVAS
>A0A4R3K8D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricomes intestini|TrEMBL
MKIIDKLKEDRIHISFEVFPPKTNAGFDKVLRATNRIAELKPDFISVTYGAGGGTSKNTA
EIARHIKEDLGVESLAHLTCASSTKDEVINVIKNLKELGIENILALRGDIPENLSFPSED
RFRHASELVTEIHKNGDFCVGAACYPEGHPESQCSKEDIRFLKEKVDRGVDFLTTQMFFE
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQIKRSVELSGTVFPRRFLAIADRFGDCPE
AMQQAGIAYAVDQIIDLLANGVRNIHIYSMNKPEVAETIMSQLSEIVKC
>A0A0H5DIP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter italicus|TrEMBL
MTTPEISFEFFPPQTLEASFRLWDTVQTLAPLGPRFVSVTYGAGGTTRDLTREAVATLHK
SSGLNVAAHLTCVNATRNETMEIADQFAAAGVREIVALRGDPPKGSGGFVPHPDGFANSV
ELIAALAERDQFSIRVGAYPDRHPEAASDRADVEWLKRKLDAGADEALTQFFFEADTFFR
FRDDCAKAGIDTSRITPGILPIENWKGARNFAKRCGTKIPAWVEDAFDKAVRDNREDLLA
TALCSELCCDLMEGGVEKLHFYTLNRPELTRDVCFALGITPKVQLENVA
>A0A0F8CU08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceratocystis fimbriata f. sp. platani|TrEMBL
MDKITDKIAALPADASYFSLEFFPPKTDMGFSNLRNRLDRMEKALHPLFVNVTWGAGGST
AQKSLQLAETCQRELGLTTCLHLTCTNMSPRLIDKALEDAKALGIRNILALRGDPPRKAE
YADANASAETQGDASTEFNYAIDLVRYIRKNHGDYFCIGVAAYPEGHADGSHPNGHSFDN
DLPLLVEKVQAGADFIMTQLFFDVAAYADFETKLRAHPSGVFNTIPVIPGLMPIQSYQMI
KRTTKLSHAKMPQALMDRLNAVQADDEQVKSVGVDILSEIITEIKRLKSGTPSPQGFHFY
TLNLEKSVSLILEKTGLIPDTDENEEAVVADDHDVSAPMRANGLMPPSVAANTQASHTTA
RRLSSIGSDPRNRVIVSAGSVGNSEYVVSAQDASLLSKPINTRANTLAASEGEGILGREV
TWDDFPNGRWGDARSPAYGEIDGYGVSLHMTPSQALQHWGYPVTADDINTLFLRHIQGDL
SALPWSEEELRPESSAIQRHLEALDMRGWWTVASQPAVNGVKSSDTTFGWGPANGFVFQK
AFVEFFLPSSAWKVLLERLRDPAVKDQVCFYASNARGDFVSSDRLDAGAADTDPATQGTT
TARVSDGPMPAEIGPSTNAVTWGVFPGKEIVTPTIIEEVSFSAWSEEAFGIWGEWARVYP
PNSASAKLLEGIRHDYYLVNVIHHDFVEPNALWDLLLEQE
>A0A3Q9BKX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jeotgalibaca ciconiae|TrEMBL
MTDSQRGGGTSLSFEVFPANTQVGTKKLIQTLNELQDLQPHFISVTCSNNKANIEETTVK
IADYVTNTLRIPTIAHLPAAYLSKQQVSTILGQLEKLGIRHVLALRGDIVEGIPPKRDFS
YASDLVTFIQEQAPYFDISGACYPEIHPDSDNRISDIKHLRKKVEAGCSQLITQLFFDNE
QFYQFKEGCSLAEIDAPILAGIMPIINRKQALRLIKVSSSQLPKKFLAILEKYEHNPVAL
RDAGLAYAIDQIVDLVTQGVAGIHLYTMNQSDTARQIHQATKSLFQTTERLGV
>A0A4S5BJL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. infantis|TrEMBL
MHSPMFSLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGERLVGDFNHASDLV
SYIRSMKPDLTVFGACYPEGHYQSGSLDQDIENLKIKVDAGVTRLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLDALLNRWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A564VFP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. infantis|TrEMBL
MHSPMFSLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGERLVGDFSHASDLV
SYIRSMKPDLTVFGACYPEGHYQSGSLDQDIENLKIKVDAGVTRLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLDALLNRWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A7X6IMY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. BG5|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVTDMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A3P3UDL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus oralis|TrEMBL
MKPNLREALKNEVIVGDGAMGTYLYHLGFPVGISYEEFNLLRPDVIGDVHRRYIRAGARL
IETNTFSANYYKLSRFGLEEKVEEINRAAVRIAREAAGDEAYVAGAVGSIRGGKRANVTA
QELGAYYEQQIATLLSEGVDALLFETFYDLREMRIALGKARHLTDLPVICQFAVDQVGRT
LDGFAMPEAFGTLLREGADVLGFNCHSGPKGIMSVMAELNGPLDVPMSVFPNAGLADYVD
GEYVYGATPEYFGENAAAFADLGARLIGGCCGTTPEHTAATAKALLGYAAPPLEKERQLP
EARSSVTLNEPEAPETESGLSPGGGQVRRDRPSLVELAKERHTVIVELDPPRDLDIGKFM
EGAAALKAAGVDALTLADNSLAVTRMSNMALGHLVQSELGLRPLIHIACRDRNLIGTQSH
MMGFDALDIDHVLAVTGDPARFGDLPGASSVYDLTSFEIIRMIKQLNDGTSFSGKPLKQK
AKFVVGAAFNPNVKHLHKAVERLEKKIASGADYIMTQPVYDPELIVAIKEATAHLDIPIF
IGIMPLASGKNAAYLHNEVPGIQLPEEILKRMEGLQGPEGRKAGVEIAKELLDTAMEHFN
GIYLMTPFMFYEMNVALVNYVKEKSKQGASHLSRST
>A0A8B9DWZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anser cygnoid|TrEMBL
WPRELSGVGHPRPSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDRWFS
LEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCG
LETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVKH
IRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFLKFMK
DCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIEL
AVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILT
INSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNYHIV
NVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEE
ESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPQPEPSEVLR
>A0A5N1GLS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aerococcus sanguinicola|TrEMBL
MKTKELFKEKTVFSYEVFPPKKSSGPQTIYKTLEELKSLSPDCISVTYGAGGGANKEESF
KIAQTIKSYGIESIAHLPCIGMTKAELEEKLDELKALQVENILALRGDLPSEDYQPGDFS
YASDMVRFIKDKGDFNVVAACYPEGHVDCKDKVQDIKHLKTKVDAGVDQLITQLFLDNQD
FYAFRERCELADINVPIEAGIMPVVNKRQIERMTSLCGVKLPDKFVKMMDRYQDKPVAMR
DAGIAYAVNQIVDLISQGVDGIHLYTMNNPYIAKKIHEAVHNLL
>F7Q3S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinisphaera shabanensis E1L3A|TrEMBL
MVSQICFDADTIECWLVRTRDRGVALPVYIGLPGVIERHKLLGIALRIGLGDSTRVLSKN
TGFWRHLALEAQPGPKIMEIIWDAALPIETSCGGCCACATCHCYIDDAWMTCLEPADADE
VDMLDMAFDVGENHSRLTCQIAFSEPLDGLRVTLAPA
>A0A0Q9TID8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrabacter sp. Soil811|TrEMBL
MAHGTASSMARAERFTRSIPAMIEADTPTYSFEFFPPKDDASEAQLWDAIRRLEKVSPSF
VSITYGAGGGTRDRTVRLTQRVLEATSLTPMAHLTCVGHSVAELRGIVGSYAAAGVRNIL
ALRGDPQGGLGQPWVAHPEGLDHADELVALVRGLGDFTVGVAAFPDGHPESGDISEDAET
LIRKERAGAEFAITQMVFDVDHYLRLRDELARRGSRLPVVPAIMPITNARQVVRMAQLAG
QPMPTAVTDRLERHGDDAAGVRAEGMAIATESSRRLLDEGAPGIHFITMNRSSATLEVFG
NL
>A0A415BW95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus|TrEMBL
MGIAELINKKKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKDGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVEAGADYVVTQMFYDNQKYVDFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAMKCKDDKEARALGIEWCINQCRELIAYGVPGIHF
YTVGAVENVKEVATAVY
>A0A2G1VKD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter guineae|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHRQGISTAPHLSCVGGTRQEIGELLDVYKDNGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLRNFARKVKAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTDMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISDREKIAF
>A0A1V9K898|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. M41(2017)|TrEMBL
MALGSASTRTDRARTVRDMLATGKQTCSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVLDTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSTEWDLDVSHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAEAGCDTPVIPEIMPVTSVRMLERLPQLSNASL
PDALKERILTVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A2H0AC05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium CG23_combo_of_CG06-09_8_20_14_all_51_8|TrEMBL
MKLKEALTRKDFVVTSEVQAPMGQEPGDLIENLKKVRGRVDGIALSESEFEGVVGDTIKT
CEALKENRFEAIYQTTTRDKNRLQLQKDLIDAHDAGIDNLLVFTEDYRITGDSLQEMMFF
HVDAGKLESVLEHIRDGHAVEGGAIGKKAEFLLGSGVESSWGKNVPDLEMKEMEEMTKLG
TGYFLTTPIFDLERFEKFLSRTNTFGVPVIAEVMILRTAGMAQFLNRHLKSGLVPEWIVQ
KLLKAPDKEKASMELFADTVKGLQHLCQGIHIITIGGEEKLRHYLDAAGLK
>A0A2S7CFJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas codiaei|TrEMBL
MHPDISRPASARIDAYSLEVGANDIDALAAVAARIMPGSLIAIPSLPGQDNATRLAAARR
IRALGFAPMPHLVARRIASLEDLRAVVGRAVDDAGVERCLVIAGDPSTSIGPFQDSLSLI
ATGVFERAGIKCIGVAGHPEGHPALPASAQWDVLERKCRNIAERGMAPLIVTQFAFDADR
VLRWLEALRARGIDHPVRVGVPGPAGVAVLARYAARCGVGASAAMLSGYGASIGKLLGTA
GPDRFVDRLAAGLSNAHGDVRLHLFPFGGIARSIGWVEQYRSRSRLTHPIDQ
>A0A5B7ZZS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter jejuensis|TrEMBL
MKVTEHLERANGKTLFSFEVLPPRKGENIKNLFSNIEPLMEFKPPFIDVTYHREEYAYRK
RPGGLLEKVTVRKRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKTESHFVPDPNGHAYASDLIAQVACMNKGHYLDEEQEDSFATDFCIGTAGY
PEKHFEAPNYGADMRYLKQKVERGANYIVTQMFFDNEQFFAFEKKCRAAGINVPIIPGLK
PMTTKSQLTMLPRTFYLNIPEALAEAVHDAPDNAAARDIGIEWCINQSKELMAHGVPCLH
YYSMGKAESIRRVAAALF
>A0A1Z7WUC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp. 42_25_T18|TrEMBL
MTNKLTISCEFFPPKTEKGIANLRNVRQQLAPLKPEFFSVTFGAGGSTQDNTLDAVVEIQ
QDKKTTGIDAAPHLSCVGSTADGIRHLLNTYQSHDIRRLVALRGDLPSGMRDPGDFRYAN
ELVEFIRQETGDHFKIEVAAYPEIHPQAQSAQADLANFKRKVEAGADSAITQYFYNIDAY
LHFIDRCQQQNINIPIIPGIMPINNFTQLARFSDGCGAEIPRWLRKQLESFHDDVESLQA
FTLDFLTEFTQKLIDAGVPGLHFYSMNRTDTTLTICQRLSLIN
>A0A7K0CP56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces smaragdinus|TrEMBL
MAHGTASTRTDRAITVRELLASGNQSYSFEFYAPKTPKGERTLWDAVRRIESVGPTFVSV
TYGAGGSSREGTVRATERIAAETTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMFAVR
GDPPGDPTGEWIRHPQGVGFAADLVSLIKESGDFCVGVAAFTNMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFYYAEDYLRLRDRAAKAGCELPIIPEIMPVTNAGQIERFAQLTNDEF
PRELADRILAVKDDKAAVRSIGIEYATELGARLLAEGIPGLHFITLNHSTATLEIYENLG
LQQRSRQPA
>A0A259V266|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa acidovorans DSM 3132|TrEMBL
MTAKLSLKAALAEPTQLSVTWELVPGRGAREKAQEHLVRMAELAAKDARINAVTITDNPS
GKSAITAYAMAVEAKRLGIDPLVHFTTKDRNRNALESELYALDRADIENLLVMTGDYPVQ
GYAGNAKPVFDFDAVHALRLIAKMNDSTYSKLTPTHFFAGAVVSPFKSTEAETMAQYYKL
HKKVASSAGFIITQLGYDARKFDEVKKYVTLNNLAVPLIGNIFVLSLPVARLMNKNLIPG
CVVTDSLLARLEEEAVDSNKKELQLLRAARQYAVLKGLQYDGVNIGGHGLGYDDVRFIME
KGEELSANWQDIAAAEFNHPQADGFYFFEKDAATGLNTCQPVDRSRTTPGRSSLKQSLMD
KVHALAFDQKAPLHPVNRAIAGYIDKSWLKQPFTMAEYITKTMTNECRFCGDCAMHELGF
ICPMSQCPKQQRNGACGGSRDGWCEVYPGKRKCIYVRMYEGFKGTGREERMKEKYMPPCN
WELYRTSSWLNYFNDRDYNHNKD
>A0A8J3VX79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerimonospora thailandensis|TrEMBL
MALGLPSRLPDRVPTVRDLLAAGERSFSFEFFPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGGSRDRTVDIVERLTHETTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNMLALR
GDPPGRDPLDEWEKHPEGVGYAEDLVRLIRQAGDFCVGVAAFPYKHPRSATIESDTEFFV
QKCRAGADYAITQMFFRADDYFRLRDRVAAHGCDTPIIPGIMPVTQMSTIARSEQLSGAP
FPPEVAARFEAVADDPAAVRRLGIEHAVELCRKLLDEGAPGIHFITFNRSSATREVFQAL
QPVGAAGSGSRAPAMT
>A0A4Q1S603|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. PK12|TrEMBL
MGLLDELKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLFETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEEAAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTRRSVIVELDPPKQLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACSGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A2S5L9D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp|TrEMBL
MKTTTKKFDVSFEFFPPKTAEGMDKLRETRTQLAKFNPEFYSVTFGAGGSTRDRTMDAVL
EIQRDGFQAAPHISCISSSKSEIRELLQAYQSQGIKRLVALRGDIPSGEVSAGDFRYASE
LVAFIREETGEHFNIEVAAYPEFHPEARTPAADLQNLKRKVDAGANSAITQYFYNADAYF
HFVDQCDALGITVPIVPGVMPIYNITQLARFSSVCGAEIPRWLKMRLEEYGDDMASLRAF
GVDVVSELCETLLAWGAPSLHFYTLNQSNIISNIIENVQQ
>A0A5P9H3V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp. THAF27|TrEMBL
MSTPTVSFEFFPPKSLEASFRLWDTVQTLAPLDPSFVSVTYGAGGTTRELTRDAVATLHK
SSGLNVAAHLTCVEATREETLAIAQDFADAGVNEIVALRGDPPKGADGFTPHPEGFADSC
ELISALADMNRFKIRVGAYPEVHPEAADAQANIDYLKRKIDAGAAEAITQFFFDTEAFFR
FRDACADAGIDAPIIPGILPIENWGGTKRFAAACGTKIPAWLDEAFTKAARDDRETLLAT
ALATELCSELIEGGAEHLHFYTLNRPELTRDVCHALGVTPKVELRDVA
>A0A1G7AHT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter pineti|TrEMBL
MKITEHIANANGKTLFSFELIPPLKGQSIQGIYDAIDPLMEFKPPFIDVTSLREDFIYKE
HDNGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLVDLQFLGIEN
VLVLRGDARRGDASFVPTPNGHNYATDLLKQVVNMNNGIYLHEHNDESLKTDFCIGIAGY
PEKHFEAPNLKTDFKYLRQKVDMGANFIVTQMFFDNQKYFDFVNNCRANGITVPIIPGLK
PVTTSKQLINLAKTFHIDMPEDLCDAVNSCKTEKDVKDIGVEWMINQCRELIKFGVPVLH
FYTMSNAGPTKRIAEAIF
>A0A1X3IU38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli TA447|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2N0TK09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum|TrEMBL
MHSPMFTLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSNRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPGLKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRAAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFLGTQG
>A0A6I1KML1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium|TrEMBL
MNFLDRMKNEVLVGDGAIGTMLYNKGVGLDANFEHLNLVRPELVMELHGEYIAAGAQVIE
TNTFGANYTKLQAIGLDRKVRDINRRGAELARRAVAGVKNGHELFVAGSVGPLVRIKGEE
KELSATEIREIYREQCGALADGGVNLFILETFSDLEQVRIALTAARETGLPVLASMAFLE
GGRTAGGAEAERVAVELAAAGADVIGANCGAGPLEILRNIRRMAAVTEMPLAAFANSGFP
EYVEGRYIYRATPEYFAGMALEMAAAGATLIGGCCGTTPDHIRRMAERLKGMKPTSRLST
AQVTFPAERQEPAVDSRGFLSPWGREKIVTVELDPPRGLDCGKVLTGSRVLKEAGADAIN
LAENPLARVRMGNIALASLIQREVGIEVIVHITCRDRNLLGLQSDLMGASLLGIRSILAV
TGDPARLGEHADASSVFDLNSFGLIKLLASLNAGVNGLGNPIGAGTGFTIGCAFNPNTPR
MEAQISRLEKKVASGASFAQTQPIYDVARLEEMLAKTARLGIPVLPGILPVVSERNCEFL
HNEVPGIDIPEEIRQRMRGKEKEAGAREGVTIAKEFIAKTRDRVGGFYIIPPFGNYGIAA
ELVHFIKGEPCLLPD
>A0A8I0JZN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium sp. zg-636|TrEMBL
MPDTDDAARQDPILQALASDRPAVSFEFFPPKDDEGEAQLWRTIDDLAPLEPTFVSVTYG
AGGTSQDRTVRITERIAREAPMPPVGHLTLVGQSRGEIETVLKQYVAAGVRHVLALRGDP
AGGPRAPWEPHPDGMSHAIELVELVREVGGLAVGVAAFPEGHPDADGLDADADVLVAKAR
AGACFAISQLFFRADDYFGLVRRVRERGCDLPIVPGIMPILNLKQVARMAELSGADMPRE
VLDQIEPLADDPKAVRAKGIDLATQLCRDLIAGGAPGLHFMTLNRSPATREIFERLRADG
VV
>A0A2V1JNA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium ramulus|TrEMBL
MIREYLKEHILITDGAMGTYYDRKKTENGRIAEEANLLEPELISRIHEEYLEQGARLIRT
NTFAANHAMALSKGIHNRQEQDAYVKKIIQTGWKLAQDAAQKRQEEIFVAADIGPVAENL
FYEDEFNETEEYRFLADCFLECGAQIFNFETFSDIKAVAIAARYIKEKCPEAFVMISFAA
NRNGYTTRGISISRLFAEAAQTPEIDSYGCNCLLGAAHMYKLIKAQKLATEKYIQVLPNS
GYQQIVRGQAGHADGVNYFAEKMEQIADLGVNILGGCCGTTPKHIRVLCEKLAGKVPQKK
LAAEKGAEDTVSQTRNNPFMAKLQRGEKVIAVELDPPFDQNAQKLMEGAFLLKQSNVDII
TLADSPLARARADSVLLAAKVSSMVDIPVMPHIACRDRNRISMHSTLLGAHINGIRNLMI
ITGDPVPSGERDNTKSVFDFNSIRFMDYVKELNHDIFLQDAFSYGGALNQNQANTDKVIE
RMKKKIDAGASWFMTQPIYSDEEVEKLARMKRELNTKILCGIMPLVSYRNAMFIKNEMPG
IQVPDEIVEQYRPDMSRGEAEDVAVRISLSVMEKLENIADGFYFMTPFNRVSLICRIIDA
RK
>A0A834MEV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhynchophorus ferrugineus|TrEMBL
MVECRVKLVKVIRRLTFSHVQSRFNTLLVRMSGSTGNKNKPFWGNNILAVDKNQNPLSVE
VSTTKEFNIDQLACINPHFVSVTWLGNKYLELPNLEAPAILLAQKLIEADLPVVLHLPGR
NLSKDRLYEILSILKEKGIRYILAIQGDWAHTVEKEDSKCDFPYASDLVLFIKDNFADQF
CVGVAAYPNLHMRCQSLEEDLKYLKQKIDNGAEFIITQAVFDYESLEKYALACREAGIEV
PIFPGIFFIKSHKSLVNMAKWCEFKVPGEILSFVEANKDDAGLIRSYGFDLGNRLIRRIL
ARGDLFAGVHIFSMNDVNFVELVAQEYKTPENA
>A0A7V4Q4H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium|TrEMBL
MKIVDQIAMGKQFLSLEFFPPKDKNEWPAFFGTVGRLARLNPLFASVTYGAGGSTQGDTL
EIVTRLKKEYGLETMAHLTCVGAYRGELRQFLDNLALAGIDNVLALRGDPPVDAQPAFSA
CRTLLHASDLASFIRDTHPGMGIGVAGYPETHPEAASAEEDLRFLKLKLQEGSDFVITQL
FFDNSRYFDFVRRARAAGVEKPIIPGIIPVVSLKVIRRIVSMCGAALPAAYLAELEEADR
LGGARAVQQLGVAYARRQAQELLAAGVPGVHIYTLNRDEAVLNLVDGLLPC
>A0A0T9PWD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia kristensenii|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMTRIFD
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A1W5Z5K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S8|TrEMBL
MALGTASTRTDHARTVRDMLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVTYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A345CG56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leclercia sp. W17|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPHWMAKMYE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0G1I7A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microgenomates group bacterium GW2011_GWC1_44_23|TrEMBL
MLEKSAERLTPPEYLKQWITEANYEVLPTEKALDLINIIPETNTISVTCRPTGIEETVHF
AEMLGPEKMKRVWPHLAARRIYSQDHFDEVSLRLINAGMEKAFIVGGDGDPSFEDFKKTE
DVLNGLLIRGILPKKIRIGGYPEGNPVMDMDPIEVLLQKQEFAEKAGVQMEIVTQMFFDA
DTLFNWLMEIRQRGVYLPVELGLLGKLKWNSFVKVLETIGIKDAMAFLKSKPKLAMSLAT
GMITGFSPRYLLTELAEKNTPELGINGISIFTLGNITNSVKCLTDIASENI
>A0A354UY08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacteraceae bacterium|TrEMBL
MDTSTAPLQRWLTGPRFSALPMQSADNPAPKLSFEFFPPRTEALEQQLWACIERLAPLVP
RFVSVTYGAGGTTQARTHATVARIARETKLVPAAHLTCIGATRDEVNEVARSYWDAGVRH
IVALRGDPAPGEKYEPHPGGYHYASDLVAGLKGVADFEISVAAYPEIHPAASSPMADLEN
LKRKLDAGATRAITQYFFDTTTYLRFLDLCLAAGIKAPIVPGIMPVSNFAQAVKFSDMCG
ASVPAWMGRLFEGTENDPETRRMIGMVVAAEQVRLLQANGVDEFHFYTLNRPDLTYAIAH
VLGVRAAF
>A0A429HLV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC 05379|TrEMBL
MALGTASIRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGDWVCHPQGLTYAAELVELIKASGDFCVGVAAFPAMHPRSVDWDADVRHFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAAGCDTPIIPEIMPIASAKTLERIPSLTNAGF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A7V4ARE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MNFLETLQDRILVADGAMGTLLSERGITFEHSYDYACLTHPADVLAIHREYIAAGAELIE
TNTYGANRFKLSQFGLEDRVEDINRAAVRLAREAADGKAFVAGAVGPAGKPLAPIGRITR
EDADASLREQISALADEGVDVFLLETFADMNELELAIRAVRDIAPGIPLIAHKTFIEDGE
TLEEGLPARVAERMRELSVDVAGSNCTVGPQRMLGIVRQMASVDGLKICAMPTAGLPQLV
GGRIHYDLTPAYFGHYGRLLAEAGAVIIGGCCGTTPAHIRAVAEAVQGMKPAAASVTAVR
EAPREALREEIEIDERSSLAKKLGLKYVVTVELDLPRGADISKVLLGAQSLKNAGADCID
ISDGARARLRMNPMAVSHLIQERVGIDVMMHFCCRDRNLLAIQADLLGCHALGLRNILAI
TGDPAQIGDYPTASSVFDVDSIGLVRILNLFNQGQDLGGNTIVEKTHFLIAVAYNPLAPD
QELERERLARKVAEGAQCVYTQPIFDERTLEVAVRDVGQHGLPLLVGILPLRSSRHAEFM
QNEVPGISIPDDIRRTIAGLADEDARRYGIETAQNFLARAKEVTQGAYLMPPFGNHATAE
AVMQALH
>A0A7V4AQQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MDLNFYRAALQAGEFVCSAELVLGRDHTLQEVQDFVGEAAREPQGVKVISLTDLPGGNPA
LPPEAFVSAVLEHGLIPIAHVSGKDVNRSFLEGRFYALARLGVKNILALTGDAQKDGFLG
RGKPVHDLDSVQILWLARTMASGIQYQLGSRAASSTPYQFFLGAVVNPFKQREPDMMMQL
YKLELKIAAGARFIIPQLGFDIRKLYEVKQYLMRRGLGHIPVLANVYVPTATVARMMQNG
ELAGCSMPPDLLRRLESEKKPQRLERAALMVAAARGLGFAGAHIGGFGLAHKDFLKILDR
ALGIGPGWRGRLDELIHECPGQFYLFPAHPEGLSDGSGAFQVSTLRPRPALRQRASDHLH
SVLIAEGSPGARFFQKRLSGHDTGWPQTVCRALLAPSAWYRKAMFGCQSCGDCIQDHLSY
AGCSVQGCYKQLRNGPCGGSRPDGNCEARPQTPCLWSRVYHSSLALGRDPGRFAETLVPP
RDWRLDGTNALVNRFTNRDNLSRRRRVLQVEEGEKDVHHR
>A0A7X6D7Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vagococcus fluvialis|TrEMBL
MTQNKLSPTLSFEVFPPNSKVGTAKLIDTLDDFKELAPSFISVTCSNSALNVEETTVSLS
GYIKQELSIPSVAHLPATYLTKERVLSVLNQLDKLGVNHLLALRGDEQPTQKPCNDFKYA
SDLITFVKEYAPQFHISGACYPEVHPDSRNRVEDIQFLKRKTDAGCDTLISQLFFDNNIF
YRFQENCALANIEKPILAGVMPIVNRNQALRLFKTNGTHLPKKFLQILDRYEHHPEALRD
AGLAYAVDQIVEFVTQNVDGIHLYTMNNSATANYIYQTTSSLFKTQKELLTV
>A0A852QY45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter aridicollis|TrEMBL
MNATLLTGSAPTRARFSFEVFPARSGAAALALGNSVQHLSAVGPDFISVTYGANGSHRDA
SLDLLAYLREHTDALPLAHLTTVRESRETIRDTIHRIMDAGIHDFLALRGDPPRGLDESS
PEVAGSLSALELTELIAEARAERPAFTSVGRTAVAAYPNGHPLSRGQSADIDWLLAKEAA
GAQFAITQLFFGADEYLGFADAARDAGLQMPLLPGLMPVSTSGQLRKVASLAGRPAPAGL
ERAMEEAGGYAPELGVEHTINLARELLAGGAPSIHLYTFNRHEQVLAVLSELDLLPTP
>A0A853AKC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora hordei|TrEMBL
MTTNAGLLEQSLNHARFEVLPLRGALAQAELLPAGTTVTVTASSTKGLESTLDLAAQLQE
RGLHVVPHLAARMVGGRGHLTELLDRVEGLGITEVFVVAGDRTEPLGEFPDALALLRAMD
ELGRRPARVGITGYPERHAFISDASTVRAMAEKSRYSDYVVSQICYDPQTVAGWVRAVRA
RGVDLPIHIGVPGVVDAHRLLRISLKIGLGESMRFLRKQHGVVPKLLTRYTPEELFDELS
PHLADPSYGIAGWHFFTFNEIAKTVQWRHDLIARLREVPA
>A0A7C3KZF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
EVPESEPSELSRKLGKKFVITVELDLPRGLDTSRVLEGAVALKEKGADMIDISDGARARL
RMAPLAVCHLIQQQAGIEAMMHVACRDRNLLALQADLLAAHALGLRNVLPITGDPANIGD
FPAATSVFDIDSVGLVRVLSRFNEGIDLAGNTVRRKCAFTIAVAFNPLAPDFQQEADRLR
RKVEAGAHLIYTQPIFEESHLERAIQTARALERPILIGCLPLRSARHAEFMHNEVPGIEI
PEWLRKRMAEADEDAALDVGIEVAQEFCARLPGMADGLYLMPPFGKHQIAERVMEAVL
>A0A7L5SSJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Rer75|TrEMBL
MALGTASTRTDRALTVRDLLASGEQSYSFEFFAPKTDKGQHTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRATEQIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVRHPDGITYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADFAITQMFFYPEDYLRLRDRVAASGCTTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDAAAVRSIGIDYATELCARLMAEEIPGLHFITLNHSTATLEIYKNLG
LHQRS
>A0A3D9SBZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus taihuensis|TrEMBL
MKPDFREVLTKCILTGDGAMGTYLYGMGFPVGVSYEEFNLIRPHVIEDVHRRYYEAGARI
IETNTFSANLASLTHYGLDNEVEAINRAGVRIARAAVGSDAYVVGAVGSIRAGKRKNIAE
AQLEQLFRQQMDALLQEGADGLLLETFYDLEEALLALRIARSLSDVPVITQFAVEKDAVT
QDGVPLTAAFEQLKQAGADVVGFNCRSGPNGILRAIDCIVGEIPLPLSVFPNAGIPDYVD
GKYTFTASPEYFAESARKFADRGARIIGGCCGTTPEHIAAIAAALNGYEPQQPDAIRETA
PTTQAETIQIKEAFTPPAQLEPNIVDVVKERHTVIVELDPPRDLDIQKFMAGAKALAEVK
ADAVTMADNSLAVTRMSNIALAALVGQQAGIRPLVHIACRDRNLIGTQSHMMGLDALGID
HVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGVAFSGKPLKQKAKFVTGAAFN
PNVKYLDKAIQRLEKKIESGADYIMTQPVYDKELIIRVAEATKQLSVPVFIGIMPLASGR
NAEYLHNEVPGIQLSDEVRKRMAGLEGEEGRAEGVRIAEELLDTAIEHFKGIYLITPFMF
YDMTVKLTDYVWRKTSKITR
>A0A8H3S147|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus udagawae|TrEMBL
MRWLRSSSINFNYSRYFPHHRGEIRVKMEKITDKIAALPPNENYFSLEFFPPKTQMGFSN
LQARLERMSQALRPLFVTVTWGAGGSTAARSLELAEICQRQLQLTTCLHLTCTNMSRALI
DEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCL
GVAAYPEGHPVDSYQDVQDPVRDLPYLVEKTLAGADFIMTQLTYDIDAYTKFEKMLRNHE
SGAFKTIPIIPGLMPIHSYKILTRTTKLSHVQIPPQIMSKLEAVKHDDDAVKRIGVDVLS
DLVEAIRKIPCPGFRGFHFYTLNLEKTVSFIIERCGLIPDDPEDFDAVVDDDYTTAPTGA
QSRSLFRRRASSVNSLPHNRVIVDRLQVPSDGSSRASTTHEAPATSAGMPAMPPDRNTTL
QISEGQGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVSGTVARRIWGYPVSRED
ISALFRRHVSGDLYIVPWSEGGAEENGSGLNAETEVIRPELLKLIDGKGWWTLASQPAVN
GVRSDDPTFGWGPPGEGFVFQKPFVEFFCPSKDFQTVLKPLFAKHGHEKLAWFATNTKGE
FESSLPADPADADTIEMNPNNVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAYRIWDEW
RRVYPRGTPTERLLDEIKNDVWLVCVVGQDFGAGTEGGSEEEQQETKWMWNVLINSQ
>A0A022XW24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton soudanense CBS 452.61|TrEMBL
MHIKDKLALAEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMPRERVDDALQSAFKAGCTNILALRGDPPREKEA
WEQTEGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFLDWVKKCRQAGIKVPIIPGIMPISTYAAFIRRTNWVKCAVPKGWMEAL
EPVKNDDAAVKQIGKALVSEMCRKLLENGINHLHFYTMNLAQSTTMVLEELNLKPSTETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSVRDLSDIFVRFLEHKLDRLPWSESAITQESEIIKDDLID
LNNRGFLTINSQPAINGAKSSHPIYGWGPRNGYVYQKAYLELLISPALIDEVVRRIESNA
DLTYHCINKDGELKTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSASRKLIQNTMDTWYLVNIGKAPSIPFVYFLTSMLTNCFSE
>A0A418QKU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus sp. RM|TrEMBL
MTRVSVELVPRSRSGLRAEIAEVAGALGGVDTVNVPDLTRYSLRSWVGCGFARPGFAAIP
HLRAVDFNPREPLPFLPLLEEHSIREVLVVTGDAPIDMSAKVYDQDAVDLIRRLNRDAPH
LRVYAGLDPYRQSFVRERDYLERKLDAGASGFFTQPFFDLRLLDTWADLLPDGTDVWWGA
TSILTEASFNYWRARNHAVFPRTFTPTLDGNRTFARDLLTFARDRQQHAYFMPVKVNVLE
YLGGIL
>A0A2E2RST0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ahrensia sp|TrEMBL
MNTIGIDTADSRPKHIPASIEISPKQAVESPDLPGLFPQGVRVYITDIGTDPTETLVAAA
RRVTDLGYTAVPHFASRRLSTKAALEDRIKATTQEAGVHDILVIGGGLEKHAGDFSSSME
VLETGFLDKYGITHVGVAGHPEGSPDFSEDVAVEALRLKKGFGERTGAKVRIVTQFGFDG
EKFIKWAEGLRAHGIDMPVHLGVAGPAKITTLVKYAAMCGVGNSLDFFKKRTRSLATLAT
SHSPEGVVGPIEKHWQDNPQTAIRQVHVFPFGGIKKSAEWLEERGTWDIKTSLYPSMNSK
S
>A0A175RNZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas ureilytica|TrEMBL
MIQRRSQRSPFRVSFEFFPPKTPKMEEGLWDSIQRLAPLSPDFVSVTYGAGGSTRERTHH
TVKRILSETPLKPAAHLTCVDASRDEVDAVVRQYRETGVRHFVALRGDGQAGAGGAYEAH
PNGYRNAVDLTAGIKAIDPEIEISVSAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNDVFERYVERVRRAGIYVPIVPGIVPIHDFTKISRFSAATGASIPLWLAERFEGLEN
DPQTHSHVAAAVCAEQVLDLVERGIGDFHFYTMNRADLVYSICHILGLRPSAGGDDRTDR
IEQAA
>A0A521QAT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellaceae bacterium|TrEMBL
MVNKPIISFEFFPPQTPEGTEKLTATRRLLATLKPEFFSVTFGAGGSTQDRTLETIRKIH
AEGYQAAPHLSCVGSTRENIRALLHTYKDMGIKRIVALRGDLPSGMGSIGEFQYANELVS
FIRAETGEHFHIEVAAYPEFHPQANSARDDMLNFKRKMHAGANSAITQYFYNADAYFRFV
EETRKLGVTAPIVPGIMPIARYSQLARFSDTCGAEIPRWMRKTLEGYGDDVESVQRFGCD
VVTQLCEKLNAGGAPGLHFYTLNQANASLEILKQLGYHA
>A0A351EUV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MAVAGHLTCVGATQQQVGKVIDDYIAAGVRHIVALRGGAPDGSTGGSVAGGYRDAADLLL
VSAGSPNAAAPQSHIGYMSSSPSSKMRPKSTR
>L2FPG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum fructicola (strain Nara gc5)|TrEMBL
MDKITDKIAALPADANYFSLEFFPPKTVMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
SQKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKSE
YRTAEDSDVEDMDDFVWAIDLVKYIRKKYGDYFCIGVAAYPEGHADESHPLGQSFEHDLP
YLVDKVQAGADFIMTQLFFDIKAYDNFEKSYQMIKRTTKLSHAKVPDALMARLDAAKGDD
EKVKRVGVDILSELVEQVKEVKSRTPGPKGFHFYTLNLEKAVSFILERTGLIPEHADDDN
ESAIIDDAVVPTVQLNGLNPMSAVPRALSNSNRRASSIGSXXXXXXXXXXXXXPAYETTA
ASLSAEPVNTRANTLAISEGEGVLGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSV
TQAVGLWGTPKTHGFVFQKSFVEFFLPSADWAGLVARLNEVKDKSICFYAANAAGDFVSS
DSSGGLVLEGTETSTNAVTWGVFPGKEIITPTIIEEVSFRAWAEEAFKIWGEWAKVYGKG
SESEALLERIRSEYWLVNIIHHDFVERDALWKLLSGEKEI
>A0A3R6VY61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. TF08-15|TrEMBL
MNNTKHTKEQIRERIQQKKILFDGAFGTYYGGKHDTRQLPELANLEAPERVKEIHREYLE
AGAQILRTNTFAANSFCMDIPREQIGETLRSGLRLAREAVAEWREATGETKEIYIAADIG
QIPGEAMAQKDALSREYEEICNIFLEEGADFFVFETFSEMEELPPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGEVKEIDAVGFNCGVGPSHMHRILQILEKPEGKLLTALP
NAGYPQMVTGRMLFTGDNKDYFVDRMQQMTALGVDMAGGCCGTTPEYIAELAGKLDLTQY
PQAKKDTEPEKQQAPKEDRSFYHTKEAEGRNRKLIAVELAPPMGIDDEKLMDAAHLLQRS
GVDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGI
QNFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFTQAPASYGGAINQGRRNL
EVEIGRVKKKMAAGATFFLTQPISTQESADRVRRIKEETGARILCGIMPFVSLKNATFMK
NEMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVIVMTEDFADGYYFSFPFNRVTMLE
KILN
>A0A6I1UMN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPSQISDIQNLKKKVDAGCSSLVTQLFFDNERLYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A4P2QAY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
MSRTRPEAPFLDALRRSILVFDGAMGSLLYERGVFVTQNFEQLNVTRPDLVKRVHADYLT
AGANVIETNTFGANRFRLERYGLVNEVRNFNLAGARLAREAAGGDAYVGGSIGPTGIVPG
VATRDDLAAAAATFAEQAGALAEGGVDLLVLETFRHLDEMKIAIEAARSSAPGLPILASM
TFDTNGAVADGSAPERVAGALRDWGVELLGVNCGDGPQLSLAMAERMVTAGLPLCVQPNA
GLPRTVDGRLLYMATPEYFDVFARRMIQAGAVMIGGCCGTTPEHVRWMAKSARMLRGSAV
AEPAARPHVAMGAPAGLAPTPLAERSPLAAKIAAGKFVVSVEVNPAPGLSPDGALAAAKM
LIDSGVDVVNVADGPRATARMTNLAFCSLLVERHGIEPILHVCGRDRNLIGQMAHLLGAH
AIGLRNLVVITGDPPKVGDYPEATAVYDLDSIGLLHMASTMNRGLDPAGKPIPGGKTSFL
LATGLEPGAQDLDKEIARLERKRAAGADLIMTQPVFHQDLLEKVLRRIEHLGMPVLVGVL
PLVSYKNAEFLHNEVPGMQIPEEIRERMRKVPAGPEARKEGVKIAREMLFAVRDRVQGAY
LMPPLGKYELALEVLDGLKTG
>A0A8J2Z2C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cysteiniphilum litorale|TrEMBL
MPNNSHISFELFPSKAHLDNGKLYQAIDEIKPHAPKYVSVTFGAGGSESYANSLTLIRYL
RQQHIDVVPHITCFHLDKQAIFSLLQEYIKLGIDRLVVVRGDLPQDIQKQTKVSFNYAYQ
LIDYIRQISGEQFDITIAAYPEFYPGSKTLQEDIDNLKQKINAGANHAITQYFYSIDAFY
HFLQMCHDHQITIPITAGVMPIANYQGLKRFSQICHADIPQWLDKRLAAYQHDPVALQDF
ASDVVAKLCDDLIDLGVHGLHFYTLNQMSATNAVIAKSSKLQSILTQQKNQRNQQAPELA
SITQLASR
>A0A3B0T5A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKVTEHLANATGPLISFEIIPPKRGGDLASLLSLIEDLAGHHPTFIDITSHSAEVVYEDT
PEGIRRRRTRKRPGTLGICALIQNKLNIDAVPHVLCEGFTREETEDFLIELHYLGIDNVL
AVRGDSLGREKRPTEGRTCNEHASDLIDQIAAMNHGRFLDDLTDASPTGFSIGAAGYPEK
HFEAPNLTADILHVKQKVEAGAEYIVTQMFFDNRHYFAFVDECRAQGVDVPIIPGLRILT
NPNQLTSIPRSFHCEIPEALAHEIESTPHRAREIGVTWATDQARELLESGTPSIHFFVLA
SSRSVDAVLAGLDV
>A0A6I1UDL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETLADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A347ZVR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelolinea submarina|TrEMBL
MTKTTFQELLTAGKPALADGAMGTLLHEKGVSFNKCFDELNLTKPSLVADIHHAYIEAGS
QIILTNTFGANRYKLGRHGMLDQLEAINTAGVDLARRVVLASFKEVLIAGDVGPLGIPLA
PFGRVQPEDARRAFREQIEVLLNADVDLLVIETMTDLYELREALTAARELSNDISIVASM
TFTRDDRTLLGDSPRKVARNLAEFGADVIGINCSGGPNQLLRILKEMHRAFPEGKYWIKP
NAGWPEQNGGRIFYPATADYFSDYALSFWRAGASVMGGCCGTTPEHIAAMRQALDSTTIT
EINGQVEIEASVETEVPETQKPTLLAQKLAKGKFVFAVEMDPPRGLSTHKVLAGASLLAE
AGADVINVADSPMARMRMSPWAVCSLVQKKAKIETTLHFPTRGRNLLRVQGDLLAAHALD
VRNVFVVMGDPTAIGDYPDAMDNYDLAPSGLIKLIKQGFNTGVDHSGSDIGQPTSFFVGC
ALNLTSPDLAREVKVINRKIEGGADFVLTQPLYSKEPVEKFLEGYREIAGTDFPLPILAG
VLPLASARHAAFLQQEVPGIDIPQPVHELMQAAGENGAREGIRLAIELIAQLRTVSQGIY
LMPAFNHFDYAAEIIEASLKS
>A0A3R9M4E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPNVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A2I8TS36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii complex sp. CFNIH9|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A3B0WSJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MQTQQKLKPNFSCEFFPPKTDKGMENLFKTADILKQEMNPEFFSVTFGAGGSTRETTFNA
VTKIKQSTGCNVAPHLSCIGSSKQQLTEILDDYKQQGINRIVTLRGDMPSGTVSQSDFSH
ANELVGFIRENYDDQFFLEVAAYPETHPQSENATQDLQHFVSKVRAGANSAITQYFYNVD
SYFYFVENCEKAGLDIPIIPGIMPITNYTNLSRFSDMCGAEIPKWLRRKLEAYADDTDSI
KAFGAEFVSIMCQKLLDMGAPGLHFYSMNQTEATLKIWNNIKP
>A0A1X7RBG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kazachstania saulgeensis|TrEMBL
MSLIETYSLKDEPSISLEFFPPKTASGKANLLERIGRMNVLDPTFVTVTWGAGGTTAEKT
IDLAGIVAQSFDIPVCMHLTCTNMEIDIIDNALEQCRELGIKNILALRGDPSIISNEDGS
PDDKFRYAVDLVKYIKDKYKDEFCVGVAAYPEGHYSTEDDSSNEQDPIRDMQFLKEKIDA
GAEFVITQLFYDADKFLDFEKMFRETISTTIPIFPGLMPINSYLLFNRAAKLSHASIPQH
IMDKFPPEIQADDNMVKSIGVNILIEIIEKIYKRTNGRVKCFHFYTLNLEKSIAEIVSES
PTLAHIIDESEDSDVEISSNDAISDEDENDMSNRHLDKDGNITLDNLYLNHDGRKRRRSS
VLSADLLFNRAIINKDSTSTRNGFNEYSYKNGMPSKKFLLSISRGSGALGRDATWDEFPN
GRFGDSRSPAYGEIDGYGPTIKVSVKKANEMWGQPTNIKDLKRIFIKYLEGSIEALPWSD
LGLSPETALIQEELIQLNHRGYLTLASQPAANAAKSTDKIFGWGPANGLVYQKGFVEMFL
HKQQWESILKPKLDHYGRRKVSYYVGDASGSFTTNLDEGSSNVVTWGVFPNSQVIQTTIV
EEESFKAWTDEAFSIWSEWAKLFPRNTPTNSFLTHIHSEYCIVSIVHHDFIETDELWEIL
LD
>A0A3B0WEA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MSSNKKATLSCEFFPPRTEAGVEKLLTTQQSLSDAFQPAYYSVTFGAGGTTRDSTLEIVK
LLTKKNISVAPHISCIGSSKQQLNDLLEIYKSLGVTRLVTLRGDIPETGESTKELSHANE
LVSFIRKTTGDHFTIEVAAYPEYHPESESPQSDFKHFKNKVAAGANGAITQYFYNIDAYL
RFMDNCQKNNITIPVTPGIMPITNFANLTRFSDICGAEIPQWIKKQLEAYADDSGSLQAF
GLDVVSNLCNQLLEQGVPGLHFYTLNRADSVNAIRKNLSL
>F8LWN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus thermophilus JIM 8232|TrEMBL
MTSQTPSLSFEVFPPNPAVGNKKILLALDDMKGSAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRELDAVGVNRILALRGDIIPGVEPLKDFRYATD
LIEFIKAEAPNFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIYAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETARHIYEATHSLFKHHSQVGAL
>Q39WH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter metallireducens (strain ATCC 53774 / DSM 7210 / GS-15)|TrEMBL
MSSTLREKLESNRFVITAEVCPPKGCDCGEFMEKARNLKGLVDAINVTDNQGANVRISPL
APAALLTREGIEPILQLTCRDRNRMALQSELLAAAALGVTNILSLSGDYISFGDHAGAKP
VFDLDSVQLLQTIAALNAGRDFSGAPLEGAPSFFAGAAAAPEADPFDLTLPKLAKKVSAG
ARFFQTQAVFSPDRLARFSEAVRPLGVKIIAGIILLKSAGMARYITKNIPGLKVPPEIVA
ELEAAGRPLEVGVAIARRLATAARPFCDGVHIMAMGREELVPNIVAGLRNEDK
>A0A0Q0B6R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. ribicola|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKADLRGLLSQYQEAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQSFG
EEVITEMCERLLQGGAPGLHFYTLNQADPSLAVWNNLKLPR
>A0A081Q8N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFSYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRSQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGMHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3B0WJJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MNNNKHFGLSFEFFPPKTEEQKAVLLDTQAKLRKLNPDFFSVTFGAGGSTITATAETVLE
LKTHETPKVIPHLSCMGGTPQEIQDLLQKYIDNGITDILALRGDVPSGMGSVGYFRYANE
LIEFIHEKHPNTFDITVGCYPEIHPETESFESEIKYFKQKVDAGVNRAITQFFFNPDAYF
NYVDHCEKAGIDISITPGIMPITNFSNIKRFCGFCGTDMPRWLQYKLQSYGDDRKSIQQF
GTEFTIKLCQQLLDQGVPGIHFYTLNRAKATLDVVKALGNARIPI
>R6MTJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:202|TrEMBL
MNIREYLKKSKLIADGSFGTYYSQKYKTVDIPEYANITASQRISEIHTEYINSGAKLIRT
NTFASNTYSLDCSIEQVKENIKAAYKIAKEAVEQSGKEIFIAGNIGPVPAVFQPDFEAVE
EEYYQIAKTFIDEGADILCFETFTQSEHIMPAIKRIKEECNPFIIVQFCVNQYGYSEAGE
SAERLVSETAFSKCVDAVGLNCGVGPAHMQQILSRINLNNNCFVTAMPNAGYPLLVRNRV
KYADNPIYFASKVNDMALLGADIIGGCCGTTPDYIREVAKTVDLTPTEKSDETSANNENE
KPVIKKSFFRNADGTIKDKKLIAVELAPPFGADDKKLLEAAHMLKGLGVDVLTFPDSPSG
RTRIDSVLMAQKVKNVTGFEVMPHICCRDKNAIAVRSTFLGASINDINNFLIITGDPIPV
MARQVVKSVFNFDSVGLMRIADEMNSEALRDSPLTYGGAINQSRRRIESEIKRVQKKMEA
GAEFFLTQPVFTAEDAERLRIVKEETGARILCGIMPLVSRKNALFMKNEISGVNVTDEVI
ERYPENADREDGENVGVELAKEMIAATRDFADGYYFSFPFNRTYLLKRIIEEV
>A0A847MAM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WS1 bacterium|TrEMBL
MSLQQAINSGKFLVTSEVGPPKGIHLEGMVEDAQACHALVDGTNVTDIQSSVMRASSLVG
CIKLQQAGIHPIMQMVCRDRNRLSLQSELLSAAAMGITDVLCLTGDYTTMGDHPQAKPVF
DLDSVQLLAVARGLMEGHDMAGNELDGEPPQFCLGCVVNPGAEPLEPQIMKLHKKIRAGA
QFVQTQAVYDTELFANFMRQAGDLGVPVLAGIVMLKSAGMANYMNKFVAGVSVPAEMIAR
MKEAQDKVQTSIEITCELIRGIRDNCQGIHLMPLGWSKHAATVIRECALA
>A0A7K1WS81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. HBTb2-11-1|TrEMBL
MKVTEHIEKAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAIDLVKQIKDLNCGKYLHEVIDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>E6KYM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aggregatibacter segnis ATCC 33393|TrEMBL
MSYAKEIDNLNQHLADLNGKINVSFEFFPPKNEKMENILWESIHRLKVLKPKFVSVTYGA
NSGERERTHGVVKHIKQETGLEAAPHLTGIDATPDELRRIAKDYWDSGIRRIVALRGDEP
KGYEKKPFYAADLVTLLREVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPAWMAKMYDGL
DDDQTTRNLVAASIAMDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGIRPTL
>A0A285NID3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. URIL14HWK12:I9|TrEMBL
MTTSDNISFEFFPTKTEAGHEKLMGVARQLAAHKPAFFSCTYGAGGSTRDRTLGTVLQLE
REVSVPAAPHLSCVGDTKAELRELLAEYKNAGIKRIVALRGDLPSGMGMAAGELRHASDL
VEFIRTETGDHFHLEVAAYPEMHPQARNFEHDLAAFATKAKAGANSAITQYFFNADCYFY
FVERVRKLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSASIQAFG
EEVITRLCEQLLAGGAPGLHFYTLNQAEPSLAIWNNLQLPS
>A0A1I3WGP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces pini|TrEMBL
MALGTPSTRTDRAHTVRELLASGERSYSFEFYAPKTEKGERTLWNAIRRVEAVAPTFVSV
TYGAGGSSREGTVRATERIATETTLTPVAHLTAVDHSVAELRNVIGQYADAGIRNMFAVR
GDPPGDPTGEWVPHPRGITYAAELVRLIKESGDFCVGVAAFPEMHPRSPDWDSDIRHFVD
KCRAGADYAITQMFFYADDYLRLRDKVAAAGCDVPIIPEIMPVTSVRQIERFAKLSNATF
PPDLAERILAVEHDPAAVRSLGIEYATELCARLMSEDVPGLHFITLNHSTATLEIYENLG
LHRRG
>A0A4S4GNB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium|TrEMBL
MKITDLFTPGRTGFSFEVLPPLKGRGIAQLFRNIDLLRQFGPLYINITTHRSEIVFRNTP
DGLYRRVSERSRPGTVAVAAAIQQKYGLPAVPHIICSGFSKIETEYALIDLNFLGISNLL
LLRGDKAKHESRFTPNENGHSHATELQTQINEFNRGFFIDGTEKDIVTDEKFSYGVAGYP
EKHEESPNIDLDIAFLKQKIDNGAEYVVTQMFFDNKKYYEFVERCRNAGIKVPIIPGLKP
ITTCSQLTMLPKTFHVDIPMELANELMKCSNDDQAKAVGVEWCKMQAADLIANKVPSIHF
YSLNAVRSVEQIARQIY
>A0A1V5NP01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin373|TrEMBL
MTYLSKLHKTLEDGHFAVTAEIGPPKHASAQGLRRHARMLGSSVDAANITDCQTAIVRLS
SIAAGVHVLSCGVEPIAQMTCRDRNRIAIQADLLGAYSLGLRNLLCLSGDHQKFGNHPAA
RNVYDLDSVQLISLVRRMRDESKFFCGEEIKENQPAFYIGAVANPFADPFEFRVDRLEKK
IKAGAQFIQTQCVFDLERFERFMELVRARGLDQRAHILAGVTPLKSWRAARYLQTGVSGM
IVPEALVERLKKAADPKKEGAAVCVEQIRYIKENIKGVHGVHIMAIAWEEIVPEIVEQAG
LAPRPATGN
>A0A4S4GJZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium|TrEMBL
MKVTELIASHGKTGFSFEVLPPLKGKGIAQLFRNIDILKEFNPLFINITTHRSEMVYKNT
PDGLYQKVSERSRPGTVAVAAAIQQKYNIPAVPHIICSGFSKIETEYALIDLNFLGITNI
LILRGDKAKHESRFIPNENGYSHASELQLQINEFNRGYFIDGTKMDIITGETFSYGVAGY
PEKHDESPNLDMDIAYLKQKIDNGAEYVVTQMFFDNSKYYDFVDRCRKAGINVPIIPGLR
PITTIGQLNILPKIFHVDMPMQLVSELMKCKDDNDAKEVGVEWCKAQCLDLMAHGVPSIH
FYSLNSTRSVERVAASIY
>A0A433KTL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas nanhaiensis|TrEMBL
MSSQEHPLGISFEFFPPNTDAGRDKLMLVRDELAARNPRFFSVTYGAGGSTQARTRDTVR
TVSQSGITTAPHLSCIGSEKAQLRDLLSQYREEGIKSLVALRGDMPSGMGSIGELRYANE
LVEFIRTETGDHFDIAVAAYPEAHPQAANLDKDIENFARKMKAGANMAITQYFFTADAYF
NFVDKVRALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWMRKQLEGYGDDSEAIAEF
GTDVVTRLCQRLLDGGAPGLHFYTLNQAAPVLKVVDNLVG
>A0A0P7FLF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus australimaris|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEDAKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSIEEIKR
SFREQLYILLNEEPDGLLLETYYDIEEAKAVLQIARKETSLPIVLNVSMHEQGVLQDGTP
LKDGLTELSSLGADVVGINCRLGPYHMIQALEGVPILENSYLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHISAMAEAVKDLAPITEKEVKVFKEEIIS
IQDKRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKSAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMAKAGEDKEKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKESNVHVNYH
>A0A1F7PEX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium RIFCSPLOWO2_12_FULL_71_19|TrEMBL
MSDALAAALRAGRFVHVVELVASRLRREAQVLDVAGRLAGLPEVVAGSITSYAGGAIGHD
PIRVGTAARARGLTPNIHLTCVSQDRRGLRKTLEDLHALGIENVFALSGDYPQGSDPGQP
PPVFDLESVQLVRMIADMRRAGMPFHISVAVSPFKYVEADCVYQYLKLEKKIAAGADLAI
TQVGWDARKLRELTRYLDQRGLRTPVLGNVYVLGKRPAERMAGGQPPGCWVSPALLAAVR
EESAARDGGRRARLERAARTVAVLRGLGYAGAYIGGTHDAEEVGWIIRRGAELAPQWEEL
AAELSYGAPDGFYLYEAPRRPGGGAAASSSTTSAHPFVPRILDTLGRLFPVRRDTALRRM
LTRFFAWADRRPPVARALERAELLVKKPLFGCQACGNCVLGDLEYVCPQTCPKQMRNGPC
GGASLGRCEVLDRPCIWVGVYERARATGRVDDLRGYIPPPDRSLQGTSSWINYFLERDSR
PGR
>A0A7X3PL03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MQFEDEPLVPGERLPIRPGHSSFGRLERVLRAGGFAVTAEIAPPDSANSAEVYERAALYD
GYVDAMNATDGSGANCHMSSVGMCSLLCRRGYAMVMQVSARDRNRIAIQGDVLGASAMGV
ASILCLTGDGVDVGDHPQAKPVFDLDCMSMLSMIRHMRDESRFLSGRKLTEPPPVFLGAA
ANPFAPPLDYRPLRLAKKVEAGAQFVQTQYCFDIDAFKRYMAAVRDAGIHEKVFILAGVG
PLASARSAEWIRANVPGVHIPDAVLRRLRGAVKQQREGVNLCIEMIRRIREIEGVHGIHI
MAYRQEHWIAEIVERSGVLEGRRPWQPPLDWQNAAWDQVHPAMPNAQGRQAMEEIS
>A4J6K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforamulus reducens (strain ATCC BAA-1160 / DSM 100696 / MI-1)|TrEMBL
MKISTLYQSQNPVISFEIFPPKSTSPVETIYETLEGLIKLEPGFISVTYGAGGSSRDRTK
EIAATIKNRYKIEALAHLTCVGQAVNEIDQILNELQEENIENVLALRGDPPADAQNYDFS
DSDFKYASDLVRHIKNSSNVCVAAAAYPEGHAHCRRLSDDLNWLKYKVDQGVDFLISQLF
FDNRIFYNFLENALRVNIHCPVVAGILPVLNAKQIKRIISLCGASMPAKLLMLVDKYGDN
AEDMEKAGIEYASQQVRDLLESGVDGIHLYTMNKPQQVTEILKNVGKA
>A0A0Q5YTB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. Leaf399|TrEMBL
MPNASQHRASRDGYLPIRVSIEFFPPKTDEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVKETGLKPAAHLTCVDASREEIDAVVQSYWDAGVRHIVALRGDPQDGIG
TAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEASSLDADIDALKAKVDAGADQ
AITQFFFENDIYLRYVDKVRAAGIDIPIIPGILPVQNFKQSANFARRTGASVPYWLAARF
EGLEDDVETRRLVAAAVAAEQVLDLVDRGVSDFHFYSMNRSDLVYAICHLLGLRSQGPKV
AVQKAAA
>A0A259P2M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomonas sp. 15-66-11|TrEMBL
MDIPNLSFEFFPPKTPEGAVKLRAARQQLYAHRPQFCSVTFGAGGSTQDGTLHTVKEIAE
EGVAAAPHLSCIGASADSIRNLLRRYRAEGIRRIVALRGDLPSGYGIGGEFHHARDLVAF
IRAETGDWFHIEVAAYPETHPQARTPQDDLRHFAEKMRAGANSAITQYFFNSDAYFRFVD
EVAAIGVDAPVVPGIMPITNASQLLRFSEVCGAEVPRWIRLRLQSFGDDRASILAFGREV
VADLCDQLLAGGAPGLHVYTLNQAAPTLDLLRDLGGR
>A6ZU57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain YJM789)|TrEMBL
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRD
AENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDVKLDLEYLKQKID
AGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQH
FSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANKCLELWSTPTSINDVAFLVINYLNGNLKCLPWSDIPIN
DEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL
>A0A3N0AF65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Slackia faecicanis|TrEMBL
MQISQVFERDGLPVSFEIFPPKGELPVEAAHALAAELSMLDPAFVSVTYSAGGSGNSERT
IDVARMAKDDFDLAMMAHLTCMGATKNDVHQVLAAMRAAGIENVLALRGDSVEGVSTADF
HFAKDLIPVAREAGFCVGAAAYPEGHIECLDFDESIRHLRQKQDAGAQFFVTQLFFDNAC
ALRFLDAALNAGVTVPITFGIMPFLSKAQISRMVFMCGASLPSPIIKLLARYENDPASLR
AAGIEYACEQLEGLAAEGVDGLHIYTMNQPAIAAAAMEALRASGAVV
>A0A0V8E2D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNVSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>A0A5R1LGW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. US12a|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A341ER43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. HI0027|TrEMBL
MTTPAVSFEVFPPRTVGAAFKLWDAAQALAPLAPRFFSVTYGAGGTTRDLTHDSAHVLHR
TSGLPVAGHLTCVGASRAETMEVADKFAEAGIKDIVALRGDPQAGTDKFEPHPDGFADSC
ELIEALAKTGKFTIRVGAYPDPHPEAADQQANIDWLKRKFDAGADEALTQFFFEADTFLR
FRDACVKAGIDKPITPGILPVVNWTSARKFAVKCGTPIPEWVDQAYEAAIRDDRHDLLAQ
AMCTELCSELIDEGVDALHFYTLNRAELTRDVCRAIGVTPQVDLSDVA
>A0A6J2HWJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pipra filicauda|TrEMBL
MDTRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTK
DDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAADLVKHIRSEFDDYFDICVA
GYPKGHPEAESYETDLRHLKEKVFAGADFIITQLFFRPETFLKFMKDCQAIGITCPIIPG
IFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMV
HGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYI
YRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVF
TCYITGEPNRNGHRVTCMPWNDDPLATETNLLKDQLEKVNRRGILTINSQPNINGKPSTD
PIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQ
PNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDN
YYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>G5GPH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas infelix ATCC 43532|TrEMBL
MAQERMDIREYLKKEPLVFDGGMGTYYAQKTHTRGKGVELANIETPLVVENIHTEYLNAG
AHAIKTNTFAANRIVYQGEEALVQGIIRTGWKLAARAAEPFGAYVFADIGPVSGLPPTDI
IEEYRFLSDTFLTAGARHFLFETNSSADGLVETAAHIKQECPGAFILTSFSAFPGGYTRD
GFFVEELVRQVAESGYIDAVGFNCVSGVQSMKELVHLLGTCPLPFSLMPNAGHPIVVDGR
TFYESAPDYFGEELADLVHDGISIVGGCCGTTPEHIRALSRALADSGRVSEDRVEQAEHA
ALGPSRSAFFEALKTGGTPIAVELDPPEVGNADKFMAGARELMEAGVHAITIADNPIARA
RMDAGMLAGRVQRSLGLEPIPHMTCRDRNLNAIKSTLLGLSAEGIHNMIAITGDPVPTAE
RDEVKSVYQFNSRKLMSFIKSLGERGDVVPFHVFGALNVNAKHFPSQLGLAKKKLEAGMT
GFFTQPVLSSRAKENLRTARDTLPGALILGGIMPVVSERNARFMESEITGIHVEERIINA
YHGLSREEAEELAVQLSLEIAKDITPYIDGYYIITPFARTALVARIVKGLKGTI
>A0A0S8AM30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium SG8_35|TrEMBL
METHDSRLRRSLKDPDEFTLTFELVPGRGGRTQEINRIVNLAKDIAADGRFQALSITENA
GGQPALSPETLGTEILAMGSEVIIHLSCKDKNRNQMESLLFGWDRHNLHNLLVIAGDYPK
EGYCGYPKPVFDLDTIHVLDLLSSMNKRGQSIQENGASGKQEKSIPFLKGVVVSPFKILE
SELVMQYYKLHRKVAAGADFVITQLGYDARKFHELLQYMKQKQLNIPVLGNVFIPSLKVV
ELMHEGKLPGCLIPDSLYEQMQWEARTADKGKKARLERAAKLLAVLKGLGYDGAHIGGPA
LTFKDLDFVLTQADQLVSDWQSLIPDLSFCPPVTFHYYEKDEKTGLNTGRETVRPPAKPP
WLSAYSFSHWVHEAAFEPEGRLYDFCKKTCLRLDETRMRGPLSTFEHITKAALFGCLNCG
DCTLEKLAFLCPQSRCAKYLLNGPCGGSHKGWCEVYPGRKRCLYVLAYERLKPYGLEEKF
KAGFIPPRNWSLNNTSSWVNFYRGLDNFAKSEDPADSCTKK
>A0A7K8KNJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ardeotis kori|TrEMBL
MVNENQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6L5Z4G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halovulum marinum|TrEMBL
MTNSSREAGGTPATLSFEFFPPATTEATMQLWRSVERLAPLAPSFVSVTYGAGGTTRART
HAAIRTIQDRARLAVAGHLTCVGASRDETLEVAETYRANGVSRIVALRGDPPKGAERFEP
HPDGFRSAAELVEALAGRGFDITVAAYPETHPEAASPDSDIENLKRKLDAGADRAITQFF
FEIDHFRRFRDRAAAAGIAAPIVPGILPIENFTRMARFARACGTNVPQWMETAFGNAATE
QDALLLAASIATEQCDLLLREGVEHLHFYTLNKPDLTYDICRALGCEPKPLGMAAGTGAA
>A0A6J4JEP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Chloroflexia bacterium|TrEMBL
RVFRVLEAMHVAAPEARLSAMPNAGWPTERNHRIFYPSTPQYMADYAKRMIEELGVSLVG
GCCGTTPEHIAAMRESLRSLRPDAPVGHTHDAPPREMSRRPLPAAPPTELARALAAREFV
VSVEIDPPRGHNPQKCIDGARMLKEAGVRFINVADSPMARVRMGPLAMCALIQQAAGVET
IIHFTTRDRSLMGLQSDLLGAHALDVRNILTLKGDPPALGSHPGTAGVFDVDTLGLVKVV
AGMNQGKDTSGHDIGVPTSFTIGVPLNHNAANVEHEIEKFRLRVAAGARFAMTQIAYDVE
GLRDFLRRLGPSPIPIILGILPLQSFRQAEFLLNE
>A0A6N3DKK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium tertium|TrEMBL
MNINNLFNEKKVVFSFEIFPPKQESNIETIYNTLEELKGLKPDFISVTYGAGGSLTKNMT
CEISSIVKNKYRIEPLAHLTCINSTKDNVDKILDDLKREGIENVLALRGDIPVDYNGEGS
FKYASDLITHIKARNDFNIVAACYPEAHPDSKSIEDDLLNLKRKQEAGATHLVSQLFFDN
NYFYDFLDKKEKYNINIPIEAGIMPVINAKQIKRIVSLCGAKVPQKFLKIMNKYEFNPEA
LRDAGIAYANEQIIDLISSGVDGIHLYTMNNPYVAKKISEGVSSIINTINSCENVVN
>A0A6M9XFG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces coelicolor|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTNFVD
KCRAGADYAITQMFFQPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A482YY22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bathymodiolus heckerae thiotrophic gill symbiont|TrEMBL
MQLSFEFFPPRTDQGKQNLREVRQQLSIIKPHYFSTTFGAGGTTQDATLETVLDIQANDG
IPAAPHLSCIDSEKSKILTLLNQYKNAGINRIVALRGDIPSGVRDIGDFHYANELVEFIR
EEFNDHFHIEVAAYPEMHPQAKNMQTDITHFVNKINAGANSAITQYFYNTDAYFRFVDEV
QKQGIDVPITPGIMPITNYDQLLRFSNMCGAEIPRWIEKRLATYGDDMQSLREFGFDVVA
NLCDQLKTQGVESFHFYSMNKSQPSLKLAQSLI
>A0A0M8YC07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis sp. NRRL B-16309|TrEMBL
MLAAPTRPVALRNPTARPRHIRELLHAGEPLFSFEFFPPRSQQAQERLWRAIREIEALGP
SFVSVTYGAGGSTRGMTVETTERIATDTTLLPVAHMTLVDHSVAELRHLIGRFADAGVSN
MLAVRGDPPGDPDGEWVRHPQGLTYTEELVRLLKDSGDFCVGVAAFPYKHPRSADVETDT
DHFVRKCDAGADYAITQMFFDPEDYLRLRDRVAARGCEIPIIPEVFPVVRTSFIPRSEQL
SGAKFPADLAAKFESFGDDAESVRAFGIEYAQRMCQRLLAEGAPGIHFITSNRSTATRQI
YQEVSGRREGRSAGVARP
>A0A0P8CVR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter excellens HL-55|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRAEIGELLDLYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARSAEDDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLETMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRQ
FGEEVVTRMCEKLLQAGAPGLHFYTLNQVEPSLSIWKNLGITDREKIAF
>A0A315D418|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. MMS-10A-160|TrEMBL
MSALKLPISLEFFPPKTPEGAEKLRVVRQTLYGLKPEFCSVTYGAGGSTQEGTFATVGAI
LSEGVAAASHFSCIGATKASVRAELATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLV
AFIRAETGDDFHIEVAAYPEIHPQAKSPEADLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGVDVPIVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGYGDDIESIKAFGL
EVVSDLCEQLINGGVPAIHFYTMNQSAATLSVLSALKSR
>A0A2T3GI51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium callitrichos|TrEMBL
MHKPMFSLEVFPPKRDAPVGTIYDTLDGLQGLDPDFISVTYGHGTHADRTATARIANTIR
KEYRIPTVAHLTALYSDEAKIDEALEMFEHAGVFAVLALRGDYIDGETPVGVFEHASDLV
RYIRDRKPDLKVFGACYPEGHIQSASLDEDIEHLKEKVDAGATHLISQLFYDNEDFYRFL
DKARAAGIDVPIEAGIMPINGAKSLRSMASKNRTRIPAAVESLLERWGSDVPTLREAGIN
YASAQITDLVAHGVDGVHLYTMNRPASTRRIWRNVRPLFETAETAEPTE
>D6LPC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella sp. NVSL 07-0026|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A382HKW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
IMLIKSFKGIKNMSNKVGINVPNWVDKTIERETEETQKVIAEDFARTQSSVLESNGFEQL
HFYTLNESKIMKNIAKHLGFYKKSTI
>A0A382AT19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
AESAIRLRDQGVRLIGGCCGTTPDHILAIAQALEGLDVVTTKRPRVVVHEPQSEAQPATE
MPVEPTVIDLVKRRVTVIVELDPPRDLRYKNTIAGSTALKEAGADAVTMADNSLAETRIS
NMAIGHIVNQEVGIRPFLHVTCRDRNLVGMQSHLLGLHALGIDHVLAVTGDPVKFGDQPG
ASNVYDISSFELIQLIKQLNRGLGFSGKELNGNTNFTVAAAFEPKYDNLDRHIRRLEKKI
ESGADMVMTQPIFDPRRAKEVYDATKHLDFPIFLGVMPLASSGNAELLHNEVPGFSIPDE
VRTRMAKVGRGPKARREGVEIAKTVADAILEYFNGIYMMTPFNRYSMTVALTKHVTGK
>A0A8H6T0P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycena kentingensis|TrEMBL
MRITRKISEADKEGKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTAEMVKTCQGLIGIETCMHLTCTNMPAAKVDIALREAKISGCRNVLALRGDPPAGKEE
WEAVEGGYVHGIDLVKHIRREYGDYFDIAVAGFPQHQLLPPDERDLEMRYLKEKIDAGVD
FIFTQMFYDVDIFIEWVHSVRAAGITIPIVPGIAPIQTWNGFMRATSLAKTIIPQTFLNA
LEPHKNDDETVRAIGTKLVAEMCRKILDANLGIRGLHFYTMNLEKGTKMLLEELNLVPRI
ETIKPLPWRQSLTPNRRTETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGEPKSFDDIAALFARFCKKDLKALPWSDQAPAGETSIIASQLA
RMNEYGFLTINSQPAVNGAKSTDPVVGWGPKNGYVYQKAYLEFFVQPELLAILLTHIERD
SNITYYVINSRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAYELGQQ
WAKIYDSGSPSRQLISDLMDKSFLVNIVHNDFHDSEAIFQPFFKAGEEYVAKLKAPQMNG
H
>A0A7V9F3F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MRELIAGGGHSYSFEFFPPKDDEGEARLWQAIRELEALQPTFVSVTYGAGGSTRDRTVRI
TERIASETTLTPVAHLTCVGHTRDELRSIIGRYADAGVRNVLALRGDPEGGPGQPWTTTS
EGLDYGVELVELVRELGDFCVGVAAFPEGHPEAADLDADAKVLVAKGKAGADFAITQLFF
QADDYFQLVERVRALGSAIPIIPGIMPITSVAQIARFAELSGTA
>A0A411MDR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas tructae|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGEHFHIEVAAYPEMHPQARNFEDDLNNFVRKAKAGANSAITQYFFNADSYFY
FVERVQQMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQQFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWSNLKLPR
>A0A382VUE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
WAVPHFSNIAAASILIENNIEPIIQFSCRDRNRIATQADVIGAHAMGVRNIFCVTGDGVQ
TGDHPEAKAVFDLDSVTLLTTINHLKTTGKFLSGRELDSKPDLFLGAAVNPFVPPFEQRA
LRLLKKHRAGASFFQSQYCFDISRFESFLLLLLELTNGSPPPVLVGVGPLRSARFARWLR
ENVPGVAIPDHIIDQIEKYPEKEQQKAGIEACVKIVEGVKNLTGVAGIHIMAHDWESSVS
EIVEATGLTKTGRNN
>A0A381PNQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MTLFSNAGRMDRSTAAPLRRRLLSAARFEVIPLNNLSSQLAHLPLGASVSVTASPNKSLE
DTWRLTSDLLSRGLRPVPHLAARMVESHQQLKRLVQELADLGLSELFLVGGDAPAPFGPY
EDSVEVLQAILELDHQLDHIGVTAYPDGHSFIESPVLSSSLRKKQQLLEEAGMQGHAATQ
MCFDSDAIREWLKRERREGLKLPIHLGIPGAVQRAKLLSVGARLGVGASLRYLQKNSGAI
GRILLPGGYNSNKLLSPLAGSLEELNVTGLHIFTFNQIEATVAWRDNAVATLKI
>A0A4Q2XRD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MHIRDILSDSKPSLSFEFFPPRTSGAWEDLYQAIRELEPLQPSFVSVTYGAGGSTREMTH
DLVVRIKQTTSIPPVPHLTCVGHSEEEVLEILRRYAAAGVSNILALRGDPPKDRPDYDWS
EGGFRHAADLVRFIRKFNDSGEHPDPRGFGIGVAGFPEGHPTTPNRVDELDFLKAKVDEG
ADYICTQLFFDNHDFFDFRDRCAIAGINVPIIAGVMPVTSLSGMKRMAELAAGARYPAKL
LRALGRAQSTPEAVERVGIHYAAEQCAGLLNERVDGIHFYTLNKSHATREIYHSLGLASE
AAAS
>A0A167GL82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga crassostreae|TrEMBL
MAALPVSIEFFPPKTPEGAEKLRAVRQQLYGLKPQFCSVTYGAGGSTQQGTFDTVGAILA
EGVDAASHFSCIGATKATVREELATLKAMGVKRLVALRGDLPSGYGSGGEFHYASDLVAF
IREETGHDFHIEVAAYPEIHPQAKSPEADLKAYVEKVNAGADSAITQYFYSSDAYARFVD
EAARLGADVPVVPGIMPITGSTQLLRFSDACGAEIPRWIRLRLQAYGDDTASIKAFGLDV
VTGLCERLRAVGAPALHFYSMNQSVATLEIARRLQLL
>A0A2E9CX31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MKKKINVSFEFFPPKNQDSIKSLWINIRRLEPLKPKFISVTYGAGGSTRINTHNLVKEIK
QNTKLEPAAHLTCIDSSMEEIEKIADEYWDSGIKHIVALRGDKPQKKNNKKNKDFNYATD
LIKVLKKKHNFKITVSAYPEMHPDSISMEQEYDVLKKKIDLGASKAITQFFFDSNYFFDF
LDGAIKRNIKIPIIPGILPVTNCRRTIEFAKKMNCKMPDSLISMFRGLDSDNETRKLVAA
TIVSDQCNKLLNGGVHDFHFYTLNRADLSFAICHILGVRSLK
>A0A1S1RB31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. Cc1.17|TrEMBL
MTAVGNMTRATTRTVAECLASGRTSFSFEFFPPKTAEGERQLWTALREIEALHPTFVSVT
YGAGGSTRDGTIRVTERIATETTLTPIGHLTAVNHSVAELRRVIGSYAGAGVRNVLALRG
DPPGDPQADWVRHPEGLAYAEDLVRLVRSLGDFCVGVAAFPDKHPRSPDLDTDARYLVRK
LDAGADFAITQFFFGADDYFRLVERVRQLGCEVPIIPGVMPVTNVAQIKRMAQLSGADFP
AALAARLHAVADDPAAVRALGIEVATELSERLLAGGAPGLHFITLNRSSATREIYQAIRP
>A0A1C7G1E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp. YL32|TrEMBL
MKIREILAEGKPTLSFEVFPPKTEDAYDSVEKAAAKIAKLKPSFMSVTYGAGGGTSDYTV
GIASAIKEEYGVTPLAHLTCVSSTREKVHHVLGELKERGIENVLALRGDIPQDGSTPKEY
HYASELIREIKKAGDFCIGAACYPEGHVESANKSVDMDYLKQKVEAGCDFVTTQMFFDNS
ILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTCLPSRFMSIVDRFGDNPAAM
KQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A2E0V914|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MQISDIFGEKKTSISFEFFPPKSEEAAERLFSAIDELKQLNPSFVSVTYGAGGSTREFTQ
RLVTRIIQETTIPTVPHLTCVCHDRQEIEAMLDQYAKAGVGTILALRGDPPAGMPEYDRS
QDAFPYASDLVAFIRDFNERGAHPTGGFGIGVAGFPEGHPETQNRITEMDHLKRKVDEGA
DYICTQLFFDNHSFLDFRDRCELAGITVPVIAGIMPITSSSGMLRIAELAAGVQFPAKLQ
QALHGLADNPEAFATAGTEYATEQCRELIQEGVKGLHFYTLNKSKATRRIAENLGLDFPP
G
>A0A1H9T5G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedococcus cremeus|TrEMBL
MALGQPSRLRRPENITRSIPRMLAAQRPSISFEFFPPKDDASEAVLWEAIRRLERVRPDF
VSVTYGAGGTTQDRTVRVTERIARETTLTPLAHLTCVNASVAQLRQVVGQYAAAGVRSIL
ALRGDPPGNVRGPWVAHPEGLDHAEDLVRLVRGLGDFTVGVAAFPDVHPESPNLEHDVEV
LVRKHAAGASFAVTQMVFDADSYLRLRDAVAARCDLPITPGLMPVTNFKQIARMSELMGT
PLPPAVVSRLEAVADDPQAIREVGVQVATELAERMLAEGAPGLHFITMNRSTATLEVYGN
LDLPVASVENAG
>A0A232EH41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichomalopsis sarcophagae|TrEMBL
MYLRRVCRLASVGRVSRRSLDSSRGMRHRVLGGDEELQVDESESVLASATPLDPGAPVNL
AGLIREKIERRESFCSYELFPTKCHGVYQRRRARRRDACRHCNQINSDKIAKRFFRDTQI
CEPLFYALTWHEGWATEEERFPSLKSAEDFPRNTLLHCTAKGLKKPDAEMILTRALELGI
ANIFALQGDSGSDDGDFDHASDLVKFIRERYGQQFSICVAGYPEMHPHSPSKELDLFYLK
AKVDAGADFILTQFFFESQLFIKFINDCREVGISVPIIPGIYPFTDVKLLRKMIEICHTN
IPDWIQEELRHIEDDDEAVRKFGIDLSVKLIKEIRESGHFCGYHVYTLNRSFSAIEVHRQ
LNTQHEIDQLVASNS
>A0A7J7IS71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bugula neritina|TrEMBL
MCVFQWSHFHIKSSIQLGVIFPIFQGYESLRHIAKLGGLNVPQSILDVVEPIKDNDEAVR
AFGIDFATQMCRDILDSGVALGLHFYTLNREVASLSILKKVGLWHEEIFRPLPWKPTANA
SRFQEDVRPIFWASRPKSYVARTSEWEEFPNGRWGNSSAATFGDISEHHLFYLRSKFTKA
QRLSMWGNQLFGEEDVWKVFHNFISGTPAENGVMVGFTQWRIISCSAL
>A0A839WHX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atlantibacter sp. RC6|TrEMBL
MSFFHANQREALNQSLAEVAGRINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRIIARDYWENGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFS
GLDEDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>Q8CJA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mus musculus|TrEMBL
MVNEARGSGSPNPRSEGSSSGSESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFS
LEFFPPRTAEGAVNLISRFDRMAAGG
>F6Z4F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mus musculus|TrEMBL
GCVRLSVPPSISRNPAMVNEARGSGSPNPRSEGSSSGSESSKDSSRCSTPSLDPERHERL
REKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDK
ETSSMMIASTAVNYCGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPVGDHW
EAEEGGFSYATDLVKHIRTEFADYFDICVAGYPRGHPDAESFEDDLKHLKEKVSAGADFI
ITQLFFEASTFFSFVKACTEIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIE
PIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDPRR
PLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYL
FYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWNDEPLAAETS
LMKEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEAL
LQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKD
EAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLNR
HPTERETQAP
>A0A7Y8K396|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas yamanorum|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQIKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNAESYFY
FVERVQAMGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A0T2L0C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Root61|TrEMBL
MAHSTPAANKAAALELVSDYSLEMTGKDVPGLIEAKDSIPAGTRINVTFLGNEDLEMRVA
AAKAVRELGFVPVPHISARRLASQEQLEEFLAALQAVGATENVFVVGGDPSTPEGPYEDS
YDVIRTGLLPKYGVKHVSIAGYPEGHPDITDDQLWSALVNKSASLKEQGLDATILTQFAF
DTDPVMNWIDQVRAKGIDTQIRIGTPGPAGIKRLLGFARRFGVGANAMIVKKYGFSLTNL
LGTAGPDTFVTDLSALLAADPKTGSVKLHFYTFGGLKATADWADKYAAAQS
>A0A5C6BZH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novipirellula galeiformis|TrEMBL
MSLESHFNSSGCAISFELFPPKTEAGIETLMKNVKRLKEFNPTFFTCTYGAGGSTRGTTL
DVVEQVKQITGLPVASHLTCVGSTVAQLEDYLDEAQTRGIDYIVALRGDPPKGTETFQAV
EGGLRYANELVELIRSRFKNFGILVAGYPEVHQEAVDAKTDLDNLKRKVDAGADVVVTQL
FYDNADFYRFRDDCVTAGISVPIVPGILPVTNFKQALRIASMCKAAIPSVLCDAMNATDC
EDSQFKIGVDHAREQTIDLIKNDVPGIHYYVLNKSDAAEKLLDGVDLN
>A0A0H2YN82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pestis bv. Antiqua (strain Nepal516)|TrEMBL
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIAIDYWNSGIRHIVALRGD
LPPNSGKPEMYACDLVGLLKDVGDFDISVAAYPEIHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFD
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A4Q5AA33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum subsp. pseudolongum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLTEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAF
IRERRPDMKIYGACYPEKHPQADTLDHDIDNLKRKVDAGVTHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDHWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWTNVQDLFA
>A0A0H2YMC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pestis bv. Antiqua (strain Nepal516)|TrEMBL
MERKLSFEMNSAKNEKEMENIFKLIEFTDTLDPIYYTVNTEIGSSVWSDTYRTVIELREK
TDVPLIPHITINNKKEREIMQIIEKYINVGICEFFVIRGDKHVYDQDNPINYGVELIELI
RRSHKHIGIKTSLYPDFHKETTEVKEEIDWNERKYQLGVNEFISQLTLNTNALDFLSHWV
DKERPFTPSIMPLGNFSFIEKFTSSNSIDYPLWIKKFANSKSNSNEDKENIGIEIIRFLC
REYLNQRERLHVFTLNKVDVMKKIFQ
>A0A3D2CWB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ochrobactrum sp|TrEMBL
MEQRLWDTVTRLAPLQPEFVSVTYGAGGSTRARTARTVARILKETDVKPAAHLTCVDATR
EEVDRVVREFASLGVNRFVALRGDPAAGIGEKYVPTPGGYQNGAELVSGLRNIADFDISV
SAYPEKHPESPDFATDIDMLKRKVDNGATRAITQFFFENDLYERYVERVRRAGIYIPIVP
GVLPVHNFKQVKNFCARSATHIPAWLAERFDGLDNDPQTHQLVAAAIAAEQVMDLIERGV
QDFHFYTMNRADLPFAICHMIGIRPKAEAALEMA
>A0A246FWN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. K2I15|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNAESYFY
FVERVRGMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLEGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1G3K1F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium RIFCSPLOWO2_12_FULL_63_15|TrEMBL
MTLNDPAAPLYADLAGDCQVSFEFFPPKSEKMEAQLWSAIETLTPLAPKFVSVTYGAGGS
TRERTHNTVARIAKETPLAAAAHLTCVGASKDEIGEIADAYWDAGVRHIVALRGDPPEVG
GTFEPHPQGYKGAADLVEGLIKRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGAIR
AITQFFFTPDAYFRFLDKVLAAGITADIVPGIMPVSNFAATQRMAAMCNTQVPSWMARLF
EGLDDHPASRQLVSATIAAELCQKLYAGGVRDFHFYTLNRSELSFAICHLLGLRAKATAD
A
>A0A0C2ZRL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp. FS06-10|TrEMBL
MFDNFYKKLHSNKPFITVEITPPHGASIDAIIXKIESIKLHEKVAGFSVTDNPLAQLKMS
GVLSAIKVQQYFHKPAIATMSMRDKNKLSLQSTLLGANDFNLRCILALTGDPAKFSDQPE
VKGVLERDSTLLLSIIYHLNNGVDYSNKELNPKPKPIYPFAVSNSYAKDMRHIKKKMLKK
LNYGARGIITQPVYDLENAKELLEIFEEAKTQSVRETAKDAELILGQFPVVRARTANFIS
DKVPGITVPKEIIDEMNLAAMDGADKEQEIGFNISKTLFDGIMKLHPKVHLMTHNRFDLC
ADLIGDN
>A0A6I4ECT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium vitis|TrEMBL
MAHTSSKRDQARPFKLSFEFFPPKSEEMEAQLWATVDELTGWAPEFVSVTYGAGGTTKAP
TLAAVRRLLAETPLATASHLTCVGATREEIAQVVEDFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGFENAAALVKGLKELGDFEISVSAYPEKHPESADLAMDLDMLKRKVDNGATRALT
QFFFDNDIFERYLDKVRAAGISIPIVPGIMPILNLTQLKRFAGMCGTSVPAMLDQRFEGL
DDKPNERASVAAALAAEQIADLQRRGIDEFHIYTMNRAPLVHATLERLGLQRSDTAVADR
AGVVA
>A0A2E8H5Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
MSRFLDALRAGTVLADGAMGSYIFELTGRLSESNHVYEAFSVDRPEVIRETHRAYLNAGS
RCLTTNTFGANRSCLAAFGLEDRAAELSTAAVVLARESIDDFARQENAGEDFFVLGSVGP
TLNSDESGTSPEETYAAQLGALVDGGVDALLLETFRDLDLLRELLAGIARLDAGIPVIVH
MALDNDSGRWNVTPEKLVSLGVEGGAHAVGINCCPPWDAEAFVEAAALTDAVADGNILLS
AMPNVGGFQHIGNRSMTRVNPEFMGQLARTMSARGTRLIGGCCEIHPAHVWEMNNYLHSR
AAGGTAVSVTIELPKERLPADAETKRDNGSFSRKILDGDFAVSVEMLPSRGTAPKLQQAK
VAFVRELSASGLTDALDITDGSRGIPLMPPGDFIQLVRGSLDWTAQTGDALELIPHFTAR
DLNVMGVQARLIGYWANRIHNAIFVTGDPPKMAPTYPPSTGVFDLDSVDMIRLAHSHLNS
GVDFGGQPLGKHRDPRTRFTIGTGFEPEAIDTPRELAKLERKLEAGADYVMTQPAFGWEP
LDVLTPFRDRAPILVGVLILRGLEHALRMRDVPGVVVPDTIVERLGSTDDVGDQVRIGQQ
IAVEQIRQIRADGWSGLYLMSPASHGPILDVLRSGLG
>A0A7S2SEQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizochromulina marina|TrEMBL
VGGVTMAPKQERGLRVLLTALAATADRGLGGRRLLQTLPPRPCCRPAPALAGRRPLATLG
CGTPNWEGIREQLRRIRQSACVEVTPTTSSGAIDKHLPVSSTGVVYVNWVEESLEHGRAV
ASMAGLLHSRGIAAIPHLPICRFGSEQELFDCMQDLRGAGVDTVLLVGGNDQKERVESGA
VPEHFRSVVKFLESPLLAEMKSCGIRAVAIGGYPEGHPAVHGDLEASEEHLKRKATAVLA
QGIDLIITTQFSFDPRTVVAWATRTKTVLDTLCADLGLEPRFEGEPARIRFHIGAAGPTP
SAQMKRISSWCQVPDQFMGSLFRAVDQDGDGRVSLLELETARDWLGVPSSFKVEQLLQTY
QYADADHASLSPLEFASMIVDFCSASRGPSSAGASPWSGILGKGPSTSITPLEHIDASTP
QHTVDDLVAPSELVLCLACLRERWRQEGRTHPVSDLVLHIFPFGGVRRARSFLQNVESES
LGLKV
>A0A1E3GFL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 51m|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHNVAGIVITPHMLRALAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVKT
KNELVPELAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDLCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A1F0PIK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC076D04|TrEMBL
MTTVHPALSFELFPPRSHASCESLIRTIAELEGTNPDYVSVTYSGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDVQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSARLAGVDIPIIPGIMPVTSLKRLRNLCQMAGMSVPADLAYALETATSSAE
LHRIGVDYALNQCRTVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEF
A
>A0A4R7SRS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecobacter fusiformis|TrEMBL
MHIKDILLAAGRPTLSFEFFPPRTADAVAVLQESLHALAPWRPDFVSVTYGAGGSTRERT
GALVGELRQSDVFDPIPHVTCVGQTEAEMQTLLEKYAAAGVSNVLALRGDLPAGTDAGGD
FQTAADLVRFIRRFNERGLHPDARGFGIGVACFPEGHPGTPNRMVEMDHLKAKVDAGADW
MCTQVFFDNHDFHDFRARCELEGIQVPILAGILPLTQASSLRRMAELAAGARYPAKLLRA
LERTRGDEEGFRQVGIHHAVMQCADLLDHEVAGLHFYTLNQAAATVQVLRGLGYTGKNR
>A0A258XY49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. 16-62-11|TrEMBL
MATPQIHPNWDKVPDGITDGFSLEMTAKDEASLRDAAPLIPAETPIAITFLPGEDVAARV
AATVAVRELGFEPMPHFSARRITSEDDFEGYLRAVVQKAGVERCFIVAGDPPEPVGPYFD
TSALIATGAFERSGIKAIGIGGHPEGHPNMSEAECWAVLEKKVADITARGMAPLIVTQFG
FDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVTN
LLGTAGPDKLVDAFAKGLTAEHGKVRLHFYPFGGLTKTLEWLHGYNKKHGIGA
>A0A517WN04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia chilikensis|TrEMBL
MRISEIYRSGTFGLSVEIFPPKSESGDAELFRTLEELVRYKPAFVSCTYGAGGSTSKRTI
ELCDTIQKDLHSTATAHFTCVGSTREQLVDWLKEASEAGIGNIMALRGDPPKGEETFIPA
DGGLKYASELVTLIRENFPEMGIGVAGYPEVHPEALTPQADLENLKRKVDAGADAIYTQL
FFNNEHFYRFQERCAQAGIDRPIIPGIMPITEYRRIQRIMSMCSSEFPAELVDRLEAAQD
DLDAQFEIGVQYAIAQCQELIDAGVPGMHFYVLNRSQACKRIFDALGWHESAD
>A0A496SUH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MNQQKSFKAGSRLEKVLLSGHFAVTAELGPPKSADLELVRRKIGYLKSYVDAANITDNQT
AIVRLSSIATATVLCQNGLEPVIQMTCRDRNRIAIQSDILGAYALGIKNILCLTGDHQSL
GNHPGARGVFDLDSIQLVQMLKVMRDEKRFLCGEEIRNSPKAPVVEPRMFIGAAANPFGD
PFELRVVRLAKKIPAGADFIQTQCIYDMKRFRQWMQQVQDKGLHQKVHILAGLTPLRSVR
MAQYMKQSVAGVTIPDEIIQRMAQAKDPAEEGVKICVEQIEELKEIEGIAGIHLMAVAWE
KIVPVIVERAGLMPRPSV
>A0A1T1HKL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MF4836|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIRQETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVISEMCERLLQGDAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A497ZSC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria conchae|TrEMBL
MTKPEISFEFFPPQTLEASFRLWDTVQTLAPLNPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLPVAAHLTCVDASRQETLEIADTFARAGVQDIVALRGDPPKGQDRFQPHPEGFANSV
ELISALAETEMFSIRVGAYPDIHPEAQNARTDVDWLKAKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGILPIENWKGARNFAKRCGTRVPEWIENAFEKAIRDDREDLLAT
ALCTELCSDLIEGGVDKLHFYTLNRPELTRDVCFALGITPQTELQNVA
>A0A0W1DLY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. H050|TrEMBL
MTSNLNSLAEARRAAATPLFANLEGDIGVSFEFFPPKSEKMEAQLWDTFRTLEPLGPRFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASRAEIDEVARAYWDAGVRHIVA
LRGDVPGGEPYRAHPNGYANAIELVAGLKKVAPFDISVAAYPEVHPDASGAEADLDNLKR
KLDAGATRAITQFFFSPEAFLRFRDSAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMVSLFEGLDDLPAARQLVAATVAAEMSRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPQAAPATEKAA
>G8BYR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5)|TrEMBL
MRITEKLVRSNGDESNGNATTAATFSFEYFVPRTTQGVHNLYDRMDRMYQESLPQFIDVT
WNAGGVNNNLTNEIVFTAQSVLGLETCMHLTCTNMDITTIDKALQQAYESGCQNILALRG
DPPLTNVGDSVGKSGNGGVGGADITDGNADADTAASGVFHYAKDLVGYIRLKYGDYFDIG
VAGYPEGHEEEKDSQLLTKFLKEKIDCGANFIVTQMFYDVDNFLNWCKLLRENGINVPII
PGVMPISTYAAFLRRARWCKINIPDEFLRKLEPVKDDDEAVREVGTQLLVDMCRKILDSG
YVSHLHLYTMNLEKAPLMILDKLNLLPHFDLDKQIDSHMTNTETTAYFDQRNSNTNETTL
SMLPWRKSLNPKRKNEEVRPIFWQKRPYTYVARTSKWAVDEFPNGRFGDSSSPAFGDLDL
CGSTLIRQSPKKSFELWSTPKTMNDLALLVISYLKGDIKCLPWSDIPISNEIDVIFDHLI
ELNQRNIITINSQPQVNGVRSNVKDIGWGPKDGYVYQKQYLEFLLPKEKLSILEQELENN
DILTFFAIDCNGNLSSNHPDGSKANAVTWGIFPGREVLQPTIVEKISFIAWKEEFYRILE
DWRNIFINNENDDSVALLNHLINDYVLVNIVDNDYIDPEDKIFTLLKRI
>A0A7V9WPF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MRIDEILAEQRPVFSFEFFPPKTDEGQDNLQATLDTLRHDRPDFVSVTYGALGSTRDRTI
GIVKWIKQDLGLETMAHFTCVGATADELRETLGEIEAAGVENVLALRGDAPEGDETWTQT
EGGLRYSTELIELLDEHFSFAVGAAAFPEVHPEADSPEADIGFLKEKQDAGARFLITQLF
FDNEFYFDFVARAREGGVTVPIVPGIMPVTSVRNIKKITELCKSEIPEAFERELVRREDD
ADAVQDLGVAYATLQCVDLLARGAPGIHFYTLNRSPATRAILAALRAAQPWTRAQQPV
>A0A1E1LDI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhynchosporium agropyri|TrEMBL
MEKITDKIAALPPGSSYFSLEFFPPKTTMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELTQRELGLTTCLHLTCTNMSRELVDQALEDAKALGVRNILALRGDPPRSEE
YRDLGEKGTGEGNVDMEEEFEWAIDLVRYIRKQYGDYFCIGVAAYPEGHADESDPAGQSL
EHDLPYVVDKVRAGADFIMTQLFFDVDAYDAFERRLREHESGVFKTIPIIPGMMPIQSYQ
MIKRTTKLSHARMPRDIMERLDRVKGDDEMVKKVGVDIVSEIVTHIQKEHAPGPRGFHFY
TLNLEKAVAFILERTNLIPSSPTDSEFAILDVPSSLESLQINGSSHKRPSRRQSSIGSDP
HNRVIISGSKAFNPTRETTADEAGIPAEPVNTRANTLAISEGEGSLGREATWDDFPNGRW
GDARSPAYGEIDGYGVSLHMSVNQAIKLWGFPTSAEDITSLFIRHIEGSIPALPWSEEGL
NEETNTIKSQLLKLNQKGWWTVASQPAVNGVKSSDPIFGWGPKNGFVFQKAFVELFIPAA
GWTSLHAKLTSSTVAPTVSWYASNASGSFLSSSPNGPEEGDGNGGGSTNAVTWGAFPGKE
IITPTIIEEVSFRAWAEEAFGIWGEWGRVYGSRSVSKGVVDGCREGYWLVNVIHHGYIER
EGLWELLLS
>A0A7X8MQH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MLIKDIFNQKKPVISFEIFPPKKYSNIDVIYSTLEALKDLRPDFISVTYGAAGSTRDKTV
EIASIIKNKYDIEALAHLTCIGLDQEGLDKIIGELIKNNVRNVMALRGDLPEGMDKKELD
SSSFAHASDIIASIKKHEDFSTGGACYPEVHPECESLDKDIENLKLKVDSGADFLVTQLF
FDNDKFYNFMDKARKAGINVPISAGIMPVTNKKQVERMISLSNATLPSKFRRILDKYEND
GEALKEAGIVYATEQIIDLLSWGIDGIHLYTMNRPETCRKIINNITSIRESLERK
>A0A7X1ZLJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
GIIPVKSAGMVRYMRDYVSGISIPDEIVIRMENAKDARREGVDICLEIIEQLKEIPGLHG
IHIMAVAWETIVPIIMNEAGLVPRPIV
>A0A852WJ31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedococcus badiiscoriae|TrEMBL
MALGHTSGVDRLRQQPLSIPGMLAAPHPSISFEFFPPKDDAGESALWDAIRRLESVRPDF
VSVTYGAGGSNQDRTVRVTERIARETTLTPLAHLTCVGASVAALRQVVGLYAASGVHNIL
ALRGDPPGNVGGEWVAHPEGLNHATDLVALVRTLGDFTIGVAAFPDVHPASPSFEHDVEV
MVRKADAGASFAITQMVFDADSYLRLRDAVAARRDLPITPGLMPVTNFRQVARMSELMGT
ALPPAVVSRLEAVSDDPAATREVGVQIATELADRMLAEGAPGLHFITMNRSTATLEVYRN
LDLSPRGTAPGTARGA
>A0A7K2VKA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID1328|TrEMBL
MALGTASTRTDRARTVRDILATGKTAYSFEFYAPKTPQGERNLWNALRRVEAVAPDFVSV
TYGAGGTTRATTVKETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEILPVTSVKMLERLPKLSNALF
PPELKERILSAKDDPAAVRSLGIDFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A6H3K7R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT4-10|TrEMBL
MSTTSEPECGRIPFSFELYPPRSDAAATALHATIATMASAGPDFISVTYGANGSSRSSSL
EVLTHILKTTTVDPMAHLTCVGSSSLEASRLIREFLDAGVRSFLALRGDPPEGAGEGEAF
LGDLGSAAELVQLIHRVQAERVPYRETVIPGIPGARAVKTEREKVRIAVAAFPNGHPRSR
STSQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRARTAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIQLEVEPTREGQREIGTRHATDLARELIAGGAPGLHLYAFNQAD
TVLAVLAGAGLIKPVLG
>A0A7W0X651|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MLSAGDKLKLLRINSFVGEASLDFLSAAATAAVEQSFEKGQLVYAKDEAATAFYVLAEGT
VGHPEVQRSDASASQINTPGQMFGFAASQLDRRTLSARCEAPTRVLALDFESFLELCRGH
GYAELPSRLAFAHKGYERDVLGRSGWISVRNVCKSFEVGEGQAALLDDCSFEVRPGELWA
LFGPKGRGKTVLLNLIAGFERVNDGVILVDGEVTNRPGMRPLHGPEHVVGYRTAIHVLRT
TVAGYLQGGEEKSEKLRLLCEQLGFAPYMASRLRDVPRDVARRVEILRAFLRDPYVVLDE
PTRGLEGDDKAALTAFVLQAHSLLPKTMLFATEDIDEAIFIADQVLVMTPAGAKKLPVAV
DVRRPRGADQRELPEFTRAKQRVLDALEKAESVAPLREGFAIEVDEALPARRLPNVANAL
KEALHEGRFFWTIEFIPSVDKVLHDALHKLGGTAEIMRQEPELVGFSVTDRVVSDRDPEP
LAPASRLLEASCKQPLVHFSGKGRDISDLHSFLERMEEHKLENMLCLTGDRLREEKKGER
ARYLESVCAIQIAKQARPELQIAAALNPFKYREEDAMAQYLKLGKKVGAGADFIITQIGF
DMHKYEEALFWVGTRNYRVPLVANLLPMAAARARYLRAHQLAGVTITDSFLALLEAEERL
MPDKGASRVLRRLALQILGVRFYGYSGVQLTGIHSVEKLSALRNEVAMLSELCSDRITWN
RAWDEALTLPEGGRANPAPSNNPWYLVNRRTKHAQVRERIKYKVMDGVHDFVFDRGLAAR
MLKAAFVPIARHSKADRVVERVERGIKAPLFGCESCGMCRLAATQYVCPETCPKGLANGA
CGGTTDNLCEFRDRECIHSVKYRIANDMGVAEQLEKWLIPAVPANIRGTSSWPPHFKDEG
PKVEVIDFLHPEQRETKGW
>A0A7X7RTE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MKIKDIFAQKKPVLSFEIFPPKKEQAFKDIDCLLKELTKCSPDFISVTFGAGGTSALAEQ
AKNPTVEIAGKIKHRYGIESVAHLTCLSYDEAEVTSILSELKSEGIENILALRGDINPNI
KPKNDFAHASDLIGYIRKSGDFGISAACYPEGHPQCQDYNLGIDHLKEKVDAGATHLISQ
LFFDNDQFFYMRDKARQSGIEVPIEAGIMPVINRAQIERMVSMCGVAFPTKFRKILDKYA
DNEKALADAGIAYAINQIVELLSHDVDGIHLYVMNKPEIAEKICSAIASMR
>A0A7L4AN69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaetusa simplex|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A662HUF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoprotei archaeon|TrEMBL
MNLLIPSYVIQRDVSIETVYQLTCRDRNRLALTSDLLAAVALGIKNILVMTGDYVTLDDD
PGQNPFLT
>A0A7W1MYE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MRIDEILEERRPCFSFEFFPPKTDEGTESLFETVSELQHDDPAFVSVTYGALGSTRDRTL
GIVKRIKQETSIEAMAHFTCVGATTEELRSTLDEMREIGIDNVLALRGDPPQGETEWRQT
EGGLKYSTELIELVRGQYPFAVGAASFPEVHPEAVDLEHDLRFLKEKVEAGATFLITQLF
FDNDHYFGFVEAARERGIDVPIIPGIIPVTNFKQLKRITGMCGASIPADFERELAEREDD
ADAVKDLGVSYATLQCADLLSRGAPGIHFYTLNKSPATRAILAALRAARPWDRALEPV
>A0A662U4D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoprotei archaeon|TrEMBL
MVRVYSELMKALLSGKFVYTAEIEAGKTANLEGIIEKAKRLKGYVTAINITDNPGACAHM
NPLIPSYVIQRDVGIETVYQLTCRDRNRLALTSDLLAAAALGIKNILVMTGD
>A0A3B7E0D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. THN1|TrEMBL
MNASYDQLREARTALDTPLFAGLPGDIAVSFEFFPPKTDALMAQLWDVVETLGPLQPKFV
SVTYGAGGSTRDRTHGTVARIIKEARLPAAAHLTCVDASKAEIREVAESYWEAGVRHIVA
LRGDMGAPGVPFTPHPDGYANAAELVAGLKQIAPFEISVAAYPESHPDSPSSQADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAAACGAA
IPAWMDGLFEGLDTHPASRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPKAPALEKAA
>A0A537C182|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MESQKKHPRTFSFEFFPPKTPGGMEKLRATWRQLAQLKPRFFSCTYGAGGSTRERTLETV
LEIQAAGHRAAPHISCIGATRADVAATLELYKSKRIDHIVALRGDLPSGAASAGELRFAS
ELVAFIRERTGDHFHVEVACYPEFHPQARSPHEDLRNFKRKVDAGADAAITQYFYNIDSY
LRFVDDCEALGIDLPIVPGIMPIGNFSQLARFSDACGAEIPRWLRLKMQSLGDDVASIRS
LGLDVVTDLCDRLLSAGAPGLHFYTMNQAGLTSTIWQRLGI
>A0A536V9R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTLPISIEFFPPKTPEGVEKLRVVRQQLYALKPEFCSVTYGAGGSTQGGTMNTVREIIAE
GCEGAPHFSCIGASRQSIREQLAMFKSDGIRRLVALRGDLPSGYGGFGEFRYASDLVAFI
RAETGDHFHIEVAAYPEVHPQARTPDADLKAFLAKVRAGATSAITQYFFNADSYFRFVDD
ARKAGVELPIVPGVMPITNSSQLIRFSENCGAEIPRWIRLRLEGYGDDRASIQAFGLDVV
TDLCERLRAGGVPGIHFYAMNMATATTEICRRLGLGK
>A0A1F3NEG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium RBG_13_42_15|TrEMBL
MESRLRNGEFVIATEVTPPLSADSGKLIRNIEMVKPFVTAVNFTDASSAIPKMSAVACCK
VASDLQAEPVYQIAARDTTRTGLQSSVIGAGQLGIRNILCVTGDNPKVGPSPTSDLNYVD
VDSVQMLWILRRMRDDGIYLDGRKMKNPPAFFLGAATSPFASDPELQAIKDQKKVNAGAQ
FFQTNLIFEPERLDQWLEHLDKRNVLEKVYILVGLVPLKSYKAAIYLHEKVPGIVIPEYI
LRRIEKAGEKAPEEGIRIALELIDSIRKKRGVNGIHLMTLGWESVVERIVTESGLFKSGN
TGAQL
>A0A2N6UZP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinotignum urinale|TrEMBL
MRRPIFSLEVFPPRRNATVGTIYDTLDGLADLQPDFISVTYGHGSQSDRTITARIAHTIR
QEYRIPVVTHLTALYSSEERVDQTLDMFEAAGVRAVLALRGDQLEGYEPQGRFNYANELV
AYIREKHTDMLVFGACYPEGHSECPDMKQDVENLKRKVDAGATTLISQLFYDNEKFYRFR
DMLDAAGITVPVEAGIMPIMSMKSTINMAKRGGVTIPKTVYLLLDKWGDDTNILRSAGVV
YASQQISDLAANGVDGIHLYTMNHPGDIRRIWGNVQNLFEKDDGRRL
>S2FR65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. G5(2012)|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLSQYKAAGIQRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A5C6EV94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Brocadiaceae bacterium B188|TrEMBL
MVENSSVIKSGSNLEKILRSGQFAVTAELGPPRGADRSAIEKKTELLKGYGDAFNITDCQ
TAVVRMSSIAAGRIVLDAGLEPIIQMTCRDRNRIAIQSDLLGAAALGAKNLLCLTGDHQK
FGDHPMAKGVFDIDSIQLIHMVKTLRDESKFQSGQELKTAGPRFFIGAAENPFADPFKFR
AIRLAKKIAAGADFIQTQIIYNTKKFKEWMKMVADMGLHEKAFILAGVAPLKSVGMARHM
KHNVPGMDVSDEIINRMTTASAAKKGKEEGIRICLEVIEQVREVKGVAGVHIMAVEWEEA
VREIVQQAQLYPRPGQENL
>A0A565BY80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabis nemorensis|TrEMBL
MKVVDKIKSVTEQGKTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGSTA
DLTLEIASRMQNVICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
QKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKENDEAVKAYGIHFATEMCKKILAHGITTLHLYTLNVDKSAIGILMNL
GLIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYGTLSDYQFLRPKARDKKLQQEWVVPLKSIEDVQEKFKELCLGSLKSSPWSELDGLQPE
TKIINDQLGKINSSGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TLVEKSKAFPSITYMALNKAENWVSNIGESDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFEIWSRNWANLYPEDDPSSRKLLEEVKNSYYLVSLVDNDYINGDIFSVFA
>A0A536ZV64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MRKRTGIFSVEFFPPKTAEGVEKLRAARRTLAELKPAFYSVTFGAGGSTREGTLETVLEI
RSEGLAATPHISCIGTTTEGVRDVLARYKDHGIRHLVALRGDLPSGAVDAGDFHYACELV
EFIRRETGEWFHIDVAAYPEYHPQARSPQEDLANFQRKVAAGANSAITQYFFNGDAYWSF
VEACVALGIAIPIVPGIMPISSYTKLARFSDACGAEIPRWIRRKLESYGDDVASIRAFGI
DVVSRLCEDLLDAGAPGLHFYTLNQATLTTTIWRRLGV
>A0A850FVE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRCIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLYGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>W1SEG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neobacillus vireti LMG 21834|TrEMBL
MSFLEKLNNQILIADGAMGTLLYSYGTDCCFEELNISQPGQIQNIHKAYIDAGADVIQTN
TYAANYLKLQRYGLEDSVKEINSAAVRNAKKAAQNNAYVLGTVGGNRGVKPDSVSIEELK
RSFREQLYCLLLEGVDGLLLETFYDLEELETILTIARKETKLPIIAQVSLQEPGILQNQT
PVNEALTRLEGLGADVIGLNCRLGPHHMLLALEQIELPKHAFLSAYPNASLPAYTDGKFH
YEGDADYFRQSAQSFRTQGVRLLGGCCGTTPEHIRAFSEELKNSVPVTEKVVKLKPKKIV
VEPSAVKREFAPLQEIVKERPSVIVELDPPRKLDTSKFFEGAKALKEAGIDSITLADNSL
ATVRISNESLGYLVKQELAMRPLIHIACRDRNIIGLQSHLMGLHTLGLNDVLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTDFSIAAAFNPNVRSLEKAVK
RLEKKIHFGADYFISQPVFSEEKLIEIYENTKHLDAPIYIGLMPLLNSKNAEFLHNEVPG
IKIADSIRERMAVLNDNPIQAAREGIAITKSLIDAALDLFNGIYLITPFLRYELTAELAI
YARQRAEELRGNIIYAENTI
>A0A7U6JIF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiolapillus brandeum|TrEMBL
MQDSDNNTSISFELFPPKTEKGMDKLKTTVARLDELKPEYFSVTYGAGGSTQERTFATVD
WLRKQGIDTAPHLSCVGADREEIAEILEHYRHQGIRRIVALRGDLPSGSGLGGMGELNYA
NELVSFIRERFGDHFHIEVAAYPEFHPQAENARADLDNFARKVHSGANGAITQYFYNPDA
YWRFLDDCNARDIDVPIIPGIMPITNYHSLARFSDACGAEIPRWIRKRLEAWGDDLDTIR
DFGEEVVSQLCRNLLDGGAPGLHFYTMNQSGPVVNICNNLGLRASAT
>A0A2X2JSR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MIPIPTKALFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDA
VTLADNSLATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEIL
AITGDPSKVGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNV
RKLDGAVKRLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNAL
FLHNEVQESRCQMKFYNNLKQLKMIKPKLVN
>A0A1I2GV42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces alni|TrEMBL
MALGTPSTRTDRAITIRELLARGERSYSFEFAAPRTDKGERTLWNAIRRIEAVGPTFVSV
TYGAGGSSREGTVRATDRIVSDTTLTPCAHLTAVNHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPLAEWVPHPQGLTYAAELVELIKDSGDFCVGVAAFTEMHPRSTDPAADTRHFLD
KCRAGADFAITQMFFDADDYLRLRDRVDAAGCSTPIIPEIMPVTNVRQIERFSQLGNAPF
PPDLAERILAVQDDPAGVRAIGIEFATEMCRRLMAEDIPGLHFITLNHSTASLEIYQNLG
LHQRT
>A0A093D0E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tauraco erythrolophus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGEK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETVLHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAADL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAAFLKFMKDCQAIGITCPI
IPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDS
GMVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPK
SYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVF
EVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNINGKP
STDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAP
DLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKLYEEESPSRMIIQYI
HDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A0W8JKI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. MEBiC08052|TrEMBL
MGYSYAGHIDALNQNISELSGDINVSFEFFPPSSPQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLVAAPHLTCIDASRDELAQIADDYWNNGIENIVALRGD
IPPGGGKPDMYAADLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDIECYLRFRDRCVSAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPGWMNKQFD
GLDDDPVTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGIRPQV
>A0A3R9XIM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC05950|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMADWVAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVEKAGCDTPIIPEVMPVVGIKQLDRLPQLSTAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A380DLB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKSSN
>H2S3I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Takifugu rubripes|TrEMBL
LVQEQRGFRSSKADSSGASNSSGESSKESSRCSTPVLDADRSDRLRDKMRRRIESGDHWF
SLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYC
GLESILHLTCCNQTKDKITGYLGKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAVDLVK
HIRSEFDDYFDICVAGYPTGHPEAESYQQDLRHLKEKVDAGADFVITQLFFRAETFLKFL
DDCRTIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITSILEPIKDNDAAIRNYGIQ
LAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWTEDPRRPLPWAVSAHPKRKVE
DVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQM
WGEELLSEESVFEVFTFYITAQSNRCGQKVLCLPWNDEPLAQETNLLKDELEKVNRRGVL
TINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHI
VNVCRPCALHSPVCVCVCARVRVCVCVCV
>A0A1R1AL79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL A5-0031|TrEMBL
MRISLELVPRDEAQLKAELDLIKTQFPAINTINIPDLTRFELRSWEASCLCKSLYESSIP
HIRAMDFDCVEPLQFIERLDQHNITEVLVVTGDIPKNSEKVVYQTTCLDLIAKIKKDHPH
IKVYSAIDPYRSSMDEEYEYVQKKLEAGADGFFTQPFFDLSLMEQYSNMVKGSEIFWGVS
PVVSDKSQKYWETRNHVVFPADFQPTLEWNIEFAKQALAFTKKTNSHIYFMPIKVDLQAY
FDGIFSKVLV
>A0A8I1MQY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIEDTLRESETTFSFEFFPPKTPEASENLYQTIRELEAYRPDFVSVTYGAGGSTRDLTH
DLVLRIKRTTSLNPVPHLTCVCHSEAEIESILTRYAEEGVGNILALAGDPPVREGYDRSK
DAFQHAADLVSFISRFNASGKHADPRGFGIGVAGFPEGHPGTPNRLLEMDYLKAKVDAGA
NYIVTQLFFDNRDFLDFRDRCSLAGINIPIIAGIMPITSLGGMRRMAELAAGARFPAKLL
RALQRGQNDPAAVERIGVHYATEQCADLLENNVRGIHFYTLNRSDATRRIFDNLGLRSVK
A
>A0A8J7SMG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Persicirhabdus sediminis|TrEMBL
MHIQDIIQKGNPTFSFEFFPPKTSAGFEALYKTIAELSPMGPSFVSITYGAGGSTREMTH
DLVVRINETTTIPAIPHLTCVAHSKEEITQTLDRYAEAGIGNILALRGDPPASMPNYKRS
DDAFQYAADLVSFIREYNQSGKHPDARGFGIGVAGFPEGHPAMPNRMKEMDYLKAKVDAG
ADYICTQLFFDNNDFFDFRERCELAGIHVPIIAGIMPIQTIASMKRMAELAEGARFPAKL
LKALNRAKDDAAVERVGIQYASQQCAELLDGKVDGIHFYTLNKSHATREIYSSLGL
>A0A7Y2LU38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 5414|TrEMBL
MTKRVPISFEFFPTKTDVGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFIIEVAAYPEMHPQAENFDKDIQHFVEKANAGANAALTQFFFNPDAYFYFI
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTHQLVIDLGLA
>A0A1X1IHZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIRLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3P2A9B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides heparinolyticus|TrEMBL
MRVIDLINSHEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLYQRNRLRRRPGTVAVAAAIQNRYNITMVPHILCSGFTREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFTPEGNGYHHAIELQEQINNFNKGIFVDGSEMKITKTPFSYGVACYP
EKHEEAPNIHTDINWLKKKMETGAEYAVTQLFYDNRKFFDFVERARLEGITIPIIPGIKP
LKKLSQINMIPKTFKVDLPEELTKEVLKCKSDKEVQQVGIEWCVQQCKELIARGVPSLHF
YSVGATDSIKEVARQIY
>A0A3M1IMR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MRFIRDIYAEAAAQGRPVVSFEFFTPKTDAGEARFFGEVLPELAALKPDYCSVTYGAGGS
TQGRTFGMVRRIQEQFGIPAMAHLTCVGARRSEIRSLLEQARADGIRNILALRGDPPQGA
ERFEPPPDGFRYAAELVAEIRAMGGFCVGVAGFPEGHLENPEGKHADWRHLRDKIARGAD
FVLTQLFFDNGYYREFRDHLRNELGVRVPLVPGIIPIQSARQIQRFTALCGATVPEG
>A0A1S1LST0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides chelonae|TrEMBL
MTTNPLDHDASVAELQDPGSIADRLAGVQPGDVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDLE
RDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEEQLLRAAGDGPEEDRDEVRKVGVEVATSMAARLVAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A2V6K2U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
RDLESYVPHFVSVTYGAGGSTRDLTHDLVERIQHTTKLDPIPHLTCVCHNEEEIQAILLR
YAKSAIGNILALGGDRPAGIAYDKSRESFQHAIDLVKFIRRFNESGAHPERRGFGIGVAG
FPEGHPATPNRLVEMDNFKAKVDAGADYVVTQLFFDNRDFFDFRERCALSQIHVPIIAGI
MPITSITGCKRMAELAGGTRFPATLLRALQHCQNNPEMVRRVGIQYALEQCHDLLDNDVA
GIHFYTLNRSDATRIIFDSLGIPRHSNTQASTV
>A0A563TZ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. dk17|TrEMBL
MKITEHIANASGKTLFSFELIPPLKGHSIQGIYDAIDPLMEFKPPFIDVTSLREDYIYKQ
HDSGLLEKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLQFLGIEN
VLVLRGDALKGDSSFVPTPNGHCYATDLLQQVVNMNNGIYLHENHEGVMKTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKIDMGARFIVTQMFFDNKKYIDFVNNCRAVGINVPIIPGLK
PITNSKQLVSLSKTFSIDIPEDLSDAIHEAKSEKDVKEIGIEWMINQCKELVEFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A0M3BBN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. LC145|TrEMBL
MKSTGAREAFGVSFEFFPPKSDEMEAQLWDTVEKLVSWNPDFVSVTYGAGGSTKAPTIEA
VRRLIHETPLATAAHLTCVDASREEVRAVVDEYRATGVRRIVALRGDPTGGIGTAYAPHP
EGYSDTADLVRALVEFGDFDISVSAYPEKHPESPDLSADIETLRRKADAGADRALTQFFF
DNDIFERYLEKVAAAGITIPVVPGIMPIQNLTQLKRFARRCGSSVPSFLDDRFEGYDDKP
EERAEIAADIAAEQIEDLMGRGIRDFHIYTMNRAPLVSAVLERLGRRRMEEKAGAAA
>A0A3N8B5W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Bp9142|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAASATRTICERLTM
>C0NNE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNILALRGDPPREKEK
WEAIEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDDQDDPDLLMQHLKEKVDAGGTF
IITQMFYDVDNFLAWVNKCRENGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEAL
EPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQATKMVLGELELIPSHKTP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGVGLKGTNEQNIKLWGEPKSLKELSEIFVRFLNGNLDRLPWSEGAVTEETDVLKLDLLD
LNRRGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNP
DLTYYCVNKKGELRTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHVASSPSRRIIQQVMDSWYLVNIVNNDFHKTHDIFNIFKDLKVENLNVQVEPIAPAAE
LVDNTRENSQDPQKQVNGSSTELTESKQEIPSN
>A0A3M1GLL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MNVDPQIAELLRQGRPLRSLEFFPPKDAAGMEALHETARALTAIEPAFVSVTYGAGGSTR
ERTAQVSTMLHEAFGFAVMPHLTCV
>A0A2V6IH85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIIDIMRGDSPTFSFEFFPPKTAQAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
GLVERIQHTTKLDPIPHLTCVCHNEEEIEAILLRYAKSAIGNILALGGDRPVGIAYDKSR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLLEMDHFKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALVDINIPIIAGIMPITSLSGFKRIAELAGGARFPAKLL
RALHRCQNDPEMVRRVGLHFAIEQCHDLLDNDVAGIHFYTLNRSDATRMIFDSLGIPRRR
NAEPSSV
>A0A2V6PW77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
KEEIRGYLNEARSRGIKNILALRGDPPGGTGEFKKTEGGFEFSYQLVEFIRQAGGFSIGV
AGFPEGHIACQEGKHVDWQRLKNKIDHGADFVITQLFFSNRDYFEFRDFLTNLGVSVPLV
PGIIPILSTAQIKKFTALCGAKLPALLVAELEKRGDNDEAAAQYGIEYATRQCEELLREG
APGIHFYTLNKTRSATAILKNLRLPCIPIDG
>H0KCM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aggregatibacter actinomycetemcomitans RhAA1|TrEMBL
MSYAKEIDNLNQHLADLNGKINVSFEFFPPKNEKMENLLWESIHRLKALKPKFVSVTYGA
NSGERERTHGVVKRIKQETGLEAAPHLTGIDATSDELRRIAKGYWDSGIRRIVALRGDEP
KGYEKKPFYAADLVALLRDVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPAWMSKMYEGL
DDDQTTRNLVAASIAMDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGIRPGL
>N9RI42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 3623|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GQGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A5B8UM28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavisolibacter ginsenosidimutans|TrEMBL
MKVIDYINEANGKTLVSFEILPPLKGKGINALWEHLDPLMEFKPSFINVTYHRSESMFKK
KPDGTFDKVEVRKRPGTVGICAALMNRYKVDAVAHLICGGFSKQETEDALIDLHFLGVNN
VLVLRGDAPKNESSFEPEPGGHRYAIELMQQVNNMNNGIYLEEDLKNATKTNFCIGVAGY
PEKHFEAPNMQTDLAFLKAKVDAGAEYIVTQMFFDNQKYFAFVKSCRDAGINVPVIPGLK
PIYTKKQLSIIPRTFHVDIPEELSSDLLKCKTDAEVEVVGQEWLLKQSKELKAAGVPVLH
YYTLGKPNVVANVVREL
>Q210B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas palustris (strain BisB18)|TrEMBL
MTEVMPAMPTRPAISFEFFPPKTEEMERTLWQAISRLAPLAPDFVSVTYGAGGSTRERTH
ATIARLLAETSLTPAAHLTCVDAPKADVDEVVARYHEVGVRHIVALRGDPSSGHGGSYAP
HPQGYQHSYDLVAAIKRRYADIEVTVSAYPEKHPESPGFDADLDMLQAKIDAGATRAITQ
CFFDNALYLRYLDRVRARGITIPIVPGILPVQSFKQAANFAARTGTSIPPWFAEKFEGLD
DDPDTRKLVAAMVAAGQVQRLAKHGVDSFHFYTMNRADLVFAISHLLGFRPNGARKAA
>A0A7H1PUK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseofuscus|TrEMBL
MNPAVSAPAAVGTDLLDDFSLEMTGKDVPALEEARGSIPQGTRINVTFLAGEDHATRLAA
ARAVRGLGFVPVPHVSARRLPSSAALEEFLAGLAEDGTADNVFVVGGDPARPEGPYEDAL
AVLRTGLLERYGVRHIGISGYPEGHPAISGPALWSALTDKARAIGAGPFTGDVITQFGFD
ADPVLDWLAAVRARGVDLPVRIGVPGPAGIRRLVGYATRFGVTTSASVARKYGFSLTNLL
GTAGPDRFLHALGERYDPARHGVVKVHFYTFGGLRTTAEWVGGFRERTR
>A0A7X4F3X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. SB0670_bin_20|TrEMBL
MKSQVGPSAFQQALASGQPVITAEISPPRGGSVQHVLTTADRLRGRVHALNVTDGSRAVM
GMSSVAVCRLLLERNLEPVLQMGCRDRNRIALQADLLGAHALGLRNVLCLTGDPVKAGDQ
PGARPVFDYEAVRLLRDVKNLNQGLDALAQPLPDGPTALFPGCAADPQSPSWSGLKRRLQ
RKKEAGAQFIQTQMVTDLAALRRFCRELAAPLGLPVLAGVFLLKSGKNARFINRMVPGAS
IPDAAIARLDAARTPRAEGLRMAAEQVAAVLEIAQGVHLMAIKAESAIPQILDLAGVPPL
APPMVDSVGPRSLAVEPR
>A0A0D1R610|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis Sbt003|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1G9GXM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus jilunlii|TrEMBL
MKPDLRSAWKNNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYIEAGAVL
LESNTYSANYDKLSKFGLEAKVGDINRAGVRIARRAAGESGYVVGAVGSIRAGKRANLSG
AELKRFYTEQFSALLEEQPDGILLETFYDVEELHLALRSVRKLSDLPVICQLAVDETART
LDGLTLPEAFHILEQDGADIIGFNCRTGPNGIKRALKSLQGSLRLPASIYPNAGIADYVD
GQYRYGASPEYFGQMAPVFADMGARIIGGCCGTTPQHIAEISAALRDYTLQPLPEPTGQR
NPEHLAVQEHLAEDGERDGREPTLVDLVKERHTVIVELDPPRDLDIAKFMRGAEALRKAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIKQLNDGIAFSGKPLKQNANFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIVRIAKATEHLEIPIFIGIMPLASGR
NAEYLHNEVPGIQLSPEVRNRMQGLEGEAGRAEGVRIAKELLDAATAHFNGIYLMTPFMF
YDMSVQLLEYVWAKQGRKLSPLFR
>A0A7X6C6C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas grimontii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISNMCEKLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A5E4K2P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon|TrEMBL
MKIKDILAGKDFSLSFEVFPPKRDGDVEILYRTIGELKKLKPDFVSVTYGAGGSSKDKTL
EIAASIKKNFGLEVLAHITCVQTTKEDTAKILNEFEGEGIKNILALRGDPPKGTERFEKT
EDGFFYASELVSFIREHNHFCIGAACYPLGHIESPSLEEDVKNLRKKVDAGTDFLITQLF
FENSQFYKFLEMTNKEGINIPIIPGIMPITSYSQIKRMAELSGHEIPKTLKNKLERIADK
PEEVEKYGRDYAAMQVMDLKMNKVRGIHFYCMNRSDIVSEILRITEQ
>A0A221K1P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter pseudonitzschiae|TrEMBL
MTALSFEVFPPKSIDAGFRLWDTVQALTPLEPRFFSVTYGAGGSTQDLTHEAAQTLRRSS
GLPVAAHLTCVGATRGKVLQTADKFADAGITDIVALRGDPVDGTGFQQVEGGFANSIELV
EALADTGRFTIRVGAYPESHADAADTAQNIAWLKAKIDAGASEAITQFFFEAETFLRFRD
ACVKAGITAPIVPGILPVGNWKTIQRFAAQCGADVPVTLGQGFENAARDGNADLFALAHC
TEMCDALRTEGVDALHFYTLNRPDLTREACRALGLIPATAMRNVA
>A0A212JKZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Alphaproteobacteria bacterium|TrEMBL
MNHPETQQARRDPLAAAGRVRVSFEFFPPKTEKMAQSLWEAVERLAPLAPEFVSVTYGAG
GSTRERTHETVVRIARETPMKPAAHLTCVAATRDEIDAVAKAYWDAGIRHVVALRGDPPD
GQSAYAPHPGGYAYASDLVAGLRRIADFEISVAAYPECHPQSRSPEDDLDNLKRKIDAGA
TRAISQYFFDADVFRRFRDRVARAGISVPVVPGILPVTNFAQVVKFSAACGASVPQWMHH
AFEGLDDDPETRRLVAATVAAAQVRALADDGIQDFHFYTLNRADLTFAICHLLGVRPQP
>A0A2J6RFP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyaloscypha variabilis F|TrEMBL
MEKITAKIAALPPSTPYFSLEFFPPKTPMGSSNLRARLDRMSHSLRPLFVTVTWGAGGST
ADRSMELAELCQRELSLTTCLHLTCTNMKREMVDRALEDAKALGVRNILALRGDPPREDY
KDGEGEGGGEEEFEWAVDLVRYIRKGYGDYFCVGVAAYPEGHADESHPEGQSLEHDLPYL
VEKVKAGADFIMTQLFFDIEAYDRFEKTLRGHESGVFKTLPIIPGMMPIQSYQMIRRTTK
LSHAKIPKRIMDRLDAVKGDDEMVKKVGVDIVGEIVMHIKDSPSPQPRGFHFYTLNLEKA
VSFILERTKLIPGSSTDFESAITEEPLPLPLPLSLQSLSINGSQTNGSHPRRSRRQSSVG
SDPHNRIIITAPRTSNPSYEATGLEAGVPAEPVNTRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGYPTSRDDITALFTRHIEGSLSAIPWSE
EGLNEETHTIKSQLLKLNQKGWWTVASQPAVNGVRSSDHVFGWGPKNGFVFQKAFVELFI
PSSDWKTLQAKLTSDEISPLVSWYASNAAGDYLSSDSGSSVESGGSTNAVTWGAFPGKEI
ITPTIIEEVSFRAWAEEAFGIWGEWGRVYGPGEKGMRSRKLVEQTAADVWLVNVIHHGYV
EKEGLWEMLLG
>A0A3M5BUN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. aceris|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPMVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A364GQ63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. 28_3|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAATATRTICERLAV
>A0A0N0FWW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. maculicola|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A0B7F0C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14)|TrEMBL
MKLSEKLANHESDVPYFTFEFFPPRTEQGYSNLLTRITGLAGLKPIAASVTWGAGGSTRD
RSLDLAGFCQTENGLDTILHLTCTNMEQGTIDDALTTAMDKGISNVLALRGDPPRGEEYW
IPTDPRFRHAEDLVTYIRQHPKFGSHFCVGVAGYPDGHSEGGNEEEQLAHLKRKVDAGAE
FIITQLFYDVDKFKLWLRKVRNAGITIPIIPGMMPLQTYATFTRMTDLCNATVPQHIQAN
LDAIKHDDQLVKEYGASLAVSMIRSILSDGDVKGVHFCTLNLEKSVRKILDELGWTHGTH
HPNQIITDASHSPHILPAPTDAPNPVTFTISPSEATQHAAISLAEHTRTGTVRTAAEAIS
SGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPPHVAISQWGRPTTEKDLSDLFLAYLNN
KNSTTPFSPTPLSDESTTILPSLVSLTSKGLWTVASQPAVDGALSSDPVVGWGPRDGRVF
QKSFVEFFTTEEELVKIAKAIEDSGDGWVTFFAGNNDDGFVSNIPDSGSNAVTWGVFPGQ
EIAQPTIIDRDSFLAWKDDAFMIWHDFGLCYPPDSPARKLLEGVAKTRWLVSIVHHDYKD
PNALWDFLAKYLN
>A0A5C3NA97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heliocybe sulcata|TrEMBL
MKLTEKIAAYQLKRPFYTFEFFPPKTDEGFENLLSRVVRLASLSPLAVSVTWGAGGSTKD
RSLELAGLIQNEEKIDTILHLTCTNMEGGMVDDALIAAKERGIQNILALRGDPPRGEEYW
IPTDPRFTHGVDLVSYIRSSAEFSSSFSVGVAAYPDGHADHDTDEDGELDYLKAKVDAGA
DFIMTQLFYDCDNFLRWLKKVRDRGITVPVIPSIMPLQTYASFLRLTKLCGSRVPDAVAS
ALEPIRHDDAQVKEYGIALAIDMVQRLTASGDVAGLHFCTLNLEKSVRRVIEGLGWAGGS
PQIRNKLIADVPDSTGSADPESTMIITPTSASNSATKGLIDSTSLPPDAGRGEKNNASSW
DEYPNGRFGDFKSPAFGEQDQWGGPVITRGEALAKWGDPKTVEDLTEIFLRHLRGEIDST
PFSHGPLSPESILILKELEKLNKRGWWTVGSQPAVDGIRSTDEVFGWGPPSGYVYQKAFV
EFFATGEDVEKIEKKIAENGDGWVDYFAGNFEGECRSNVPDGGRNAVTWGVFPGQEVLQT
TIIERESFLSWKEEAFSILSEWASFYAPGSEQRKLLKDIRDQRWLVSIVHHDYKDASALW
TFLGGQNGLV
>A0A0B7FZM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14)|TrEMBL
MKVTEKIQQAEKDGRVWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSELVKTCQGVIGIETCMHLTCTNMHQEKVDIALREAKANGCRNILALRGDPPSGQEE
WTSVEGGFQHGVDLVRHIRREYDDYFDVSVAGFPQTIQLPEAEAKQEMQWLKEKCEAGAN
FIFTQMFYDADMFIRWVKAAREAGITVPIVPGINPIQTWNGFIRATSLSGTDIPQDLMDI
LEPHKNNDEKVRELGTKIVADLCRKILDADIGIRGLHFYTMNLEKGTKMLLEELNLVPRV
ETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQTPEEGRKIWGTPTTMDDIKDLFTKFCSQQIKALPWSDQPPTTEMLVIGQQLA
RMNELGYLTINSQPAVNGARSDDKAFGWGPKNGYVYQKAYLEFFVHPAQLQALIKRIERD
TNVTYYAINKQGDLKTNSTSEGPTAVTWGVFPGKEVVQPTIVEAVSFMAWKDEAFELGCQ
WAKIYESGSPSRKLIEGMMDEYFLVNFVHNDFHDREAIFRPFFADAGLKANGNSETPAVN
GVKHANGLVNGHSTAVHA
>A0A3N4RQW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora niigatensis|TrEMBL
MALGIPSTRSDRAQTVRDLLAAGDRSFSFEFMPPRNEEGERKLWDAIRRVECLEPNFVCM
TYGAGGSSRGRTVDLVGRIATETTLTPVAHLTAVDHSVAELRNIIGQYADQNVRNVLAVR
GDPPGDPMGEWVRHPEGVSYAAELVGLIKDIGDFCVGVAAFPQMHPRSENWDEDIRHFVA
KCRAGADYAITQMFFEVEDYLRLRDRVAAAGCDTPIIPEIMPVTNIRQLVRFPQLSGSDF
PPDFRRKLESVADDPVAVRAAGLEHATAMAERLLAEGAPGLHFITLNHSTSTLEIYQNLG
LHTR
>A0A841LRI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenochrobactrum gallinarii|TrEMBL
MRFNGLSRRSEVGKNLRVSFEFFPPKSEEMENRLWETVTRLAPLEPEFFSVTYGAGGSTR
ERTARTVQRILTETNVTPAAHLTCVDATRAEVDQVIRDFAAMGVKRFVALRGDPASGVGN
AYVPTPGGYNNGSELVAGLKTIDDFDIIVSAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIFPVHSFKQLVGFCARSGQHIPEWLAERFE
GLDNDPHTHQLVAAAIAAEQVMDLIERGLQDFHFYTMNRADLPYAICHMLGVRPKHAAEA
>A0A0E1VLA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus USA300_TCH959|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A7Y5FGQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MRIPFLQHLQHDLLIADGAMGTMIYSQGVALSQSFDQLNLTQPELILGIHRAYVQAGAQA
VETNSFTANRKRLARYGLEKSVREINLAAVRLARSAAGEQAYVLASLGPVRDRASEEMET
VEIRSLFAEQIAALVEGQPDALIFETFTVVSELEIAVEEARRLSAIPVIAQVVADEEGYT
SDGQHLTAIFKRLRALGAAVVGINCAKGPAGILKALREVPLEEGLLLSAFPNAGLPAYVD
GRYIYLSTPEYFGEAALKLRQQGVRLIGGCCGTTPEHIQAIAESLRGLPPVNDKIISVRP
APPPPSLQEIITPDFLTKVKTRPAIIVELDPPRDLDFEPILQGARELKRAGIDALTMADS
SLGITRMNNLALGALIKQKVDMPLIIHLACRDRNLVGLQSELMGLHALGLHTVLALTGDP
AKFGDQPGATSVFDLNSFGLVEMIKRMNQGIAFSGRAMKQGTRFVVGVAFNPNVDRLDTQ
VRRLHKKIQAGADFVMTQPIFDWRMAKELHTTTRDLDIPVFIGIMPLVSGRNADFLHNEV
PGIRVPEKTRKRLFRFEGERARREGVTIAAEVLESVLDYFNGIYLITPFVRYEMCLELIE
KCRALVRRSESAKTGRVKV
>A0A6I3K8K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium aurimucosum|TrEMBL
MSPRLSASAPLDQISEDTPKELKRTALSFEVIPPRHDADAAKIDRLLATLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTEEELVGWIDTLVDAGVRGLLALR
GDLPEGGMPEGHLPHADSLVRLIRRWESDRVARLAAGRLAVGVACYPNGHAESATPDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTKVLDQLAAATSPEEEKEIGMQITASLAKSVMNAGADGLHIYTHNNPDITTDLL
HRIGVTP
>A0A8C5AMH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gadus morhua|TrEMBL
AVKTARHKHNASPALSSGASNSGESSKESSRCSTPLLDADRSDRLREKMRKRMESGDPWF
SLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSNKETSSMMIASTAVNYC
GLESVLHLTCSNQSQETITGYLTKAKQLGLKNIMALRGDPLGTDWEDEEEGFNYATDLVK
HIRSEFDDYFDICVAGYPTGHPEAQSYAEDLQHLKEKVDAGADFIITQLFFRADTFLKFL
RDCRAIGITVPILPGVFPIQGYQSLRQLVKLSKLEVPEEIMEVIEPIKDNDAAIRSYGIH
QAVEMCRVLLDSGAVPGLHFYTLNREVATTEVLRQLGLWIEDPRRPLPWATSANPKRKVE
DVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKM
WGEELTSETSVFEVFTSYITAQVNRGGHKVMCLPWNDDALATETNLLKDELEKVNRRGVL
TINSQPNINGKPSSDPIAGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHI
VNVQGHNMTNAQDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYE
DESPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQVLDDMFELLDAVFYFERPNQATFSYL
FVFYVFLKDDSEEMLFR
>A0A7I9K8Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter hyointestinalis|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEIEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A7X0H3L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algisphaera agarilytica|TrEMBL
MHIQDLFAQHSTTFSFEFFPPKSAEASEALYSTIADLGSLKPAFVSVTYGAGGSTRELTH
DLVERIKTTTDTSAVPHLTCVCHSDSDIQEVLERYASIGVSNLLALGGDPPRNLENYSKA
DDYFQHAADLVKFIREFKGHPDPRGFGIGVAGFPEGHPGTPNRMLEMDYLKAKVDAGADY
ICTQLFFDNHDFYDFRERCELAGIHVPIIAGIMPITSAKGMKRMAELAAGSRYPASLLRA
IKRCGDDEEAVANVGVHWATEQCRDLLDNKVAGIHFYTLNKSDATRQIYRSLGAADSVAL
GQ
>A0A660YJ35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MEDFRKHVKKNIVLFDGGMGSLIYQRGIFLNKSYDELNLSNRDFILSIHKEYISAGADVI
ETNTFGANFYKLRKYNLQKKVEEINIKGAEIAVEAADSKVYVCGSIGPLGVKIEPWGEIS
YKEARQAFKDQISALIKGGVNILLFETFQEITELKQAIYAAREVTDIVVIAQMTIRDDGK
TIYGLSAEEVASELCKTDADIIGMNCAVGPKSMLENLEKFIPFSSKPVSVMPNAGRAQFI
EGRTIYMSTPEYFGVYARRFIDAGARIIGGCCGTTPDHIMKMADSVRQKQGRQSIRIGKV
KDLSGDYFSPEIVNPEEKSEFASKLYNGKFATMVEMVAPRGNDLTKHIRGAKLLKDSGID
VINIPDGPRASARMNGMALACKIQQNVGIETVLHYTCRDRNI
>A0A6A0HHJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MKVSFLEHLQQDLLVADGAMGTMIYSQGVALSQSFDQLNLTQPDLIRGIHQAYVQAGAQA
IETNSFTANRKRLARFGLENSVAEINLAAVRLAREAADEQAYVLASIGPVRDRASEEMES
ADIRQLFAEHISALAQGRPDALLFETFTVVSELEIAVEEARRLSSIPIIAQVVADEEGYT
SDGQHVTAIFKRLRELGAAVVGINCAKGPAGILKALRDVPLEESLLLSAFPNAGLPAFVD
GRYIYLSTPEYFGEAALKLRQQGVRLIGGCCGTTPEHVQMMANTLRGLKPVTEKTIVLRP
APAPPSLQKIIEPDFLQKVRTQPSIIVELDPPRDLDFEPIVEGARALKRAGVDALTMADC
SLGITRMNNLALGYLVKQKVDIPLIIHLACRDRNLVGLQSELMGLHALGIHTVLALTGDP
AKFGDQPGATSVFDLNSFGLVEMIKRMNQGIAFSGRAMKQGARFTIGVAFNPNVERLDTQ
IRRLRKKVEAGADFVMTQPIFDWRMTKEIYDATREFDIPIFIGIMPLVSGRNADFLHNEV
PGIRVPEKIRKRLFRFEGERARREGVTIAAEILESVLDYFNGIYLITPFVRYEMCLELVE
KCRGLVRRSK
>A0A836S721|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichales bacterium|TrEMBL
MESQKQHARVFSFEFFPPRTDAGVEKLRATRKQLVALKPRFFSVTFGAGGSTQERTLETV
LEIQKKSGIEAAPHLSCIGSSRENIRKILQTYQDNGVKHIVALRGDMPSGLGEPGAFHFA
NELVEFIRAETGDHFHIEVAAYPEFHPQAPDANTDLDNFKRKTEAGADSAITQYFFNPDA
YFRFIESCEQRGLSLPIVPGIMPITNYKNLARFSDACGAEIPRWIRKRLEVFGDDLASVE
ALGVDIVTTLCQRLLDEGAPGLHFYTMNRAEPTTTIWKNLGI
>A0A7G2C5W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Angomonas deanei|TrEMBL
MPKGLIMEGLEFAKAHDIRNILALRGDPPAGQEFKANPDGFTCALDLIKFIKEKYGDHFS
ISTAGYPEGHPGKLDDEGKITPEDYKKEIEYLKAKVDAGARIIITQLFYDADIFIKFVKD
CRAAGITVPILPGLLPVTRYASLQRMVNLCKTYMPPEMKKKVEEVKDDDEAIKAYGVSQC
VEMINKIRAADIGVNHFHFYTINDCAQSFRVLQELGVYNE
>A0A1G6QRT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides lianchengensis|TrEMBL
MSIEHGRSLADLIAEGGRSFSFEFFPPKDEAGEEQLWRAISDLEPYRPTFVSVTYGAGGA
TRGTTVRITGRIARETSMLPVAHLTCVGHTEAEIEHILDTYSAAGVTHVMALRGDPSEGP
RAPWTPTEGGLTYASELVELVRRRGDFRVAVAAFPEGHPTAESLDHDADVLVAKARAGAE
FAVTQMFFRASDYFALVERVRARGVDLPILPGIMPILNLNAIRRQGELIGADVPAEVVER
ISAYDGDPVALRAEGIKVAAELCEDLLAGGAPGLHFYTLNRSKATLEIFEALNVGV
>A0A180FMM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium Barb6|TrEMBL
MKVIDLISSGKQPAFSFEILPPLKGNTIKNVYSVIDKLHEFAPRYINITSHHSEHQYKTL
PDGSFQKVSIRKRPGSVAIASAIQNKYHIPAIPHIICKGFTKEETEYAMIDLNFLGVHDL
LLLRGDNKSQETQLSPDLYHSHATDLQQQVNNFNRGIALDGSAFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNAKYYAFVERCRAEGITVPIIPGIKPV
VFKNQLTVLPRIFRSDIPEPFAAELRKCKDDEAAKAAGIEWCVSQCKDLAAHGVPGLHFY
TFMASDSVYKVAKEVY
>A0A2G9V5Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Teladorsagia circumcincta|TrEMBL
MVVAAKQNSVSNGGDTHEQLKKIAIPYVLDRFNEGGPLFVDITWHLGSDPANMNKETSSS
SIAAGCLDYCRVDTMLHMTCAQYSKEQTIKHLEQSKSVGLRNILALRGDLPIMETDGVPV
YKYRALDMIRWIREEFGDYFTVCCSGYPLGHPEAPSYKADLLYLKSKCEAGAQFIITQLF
FEAEVFEEFVRDCREIGITVPIIPGIMPIMAIEMCRRILSNGSAPSIHLYTMNREGACRE
ILQELGLWHKRPMRTLPWKPHGSIHPLRCKEDVRPIFWSARPKSYIYRTRDWDDFPNGRW
GNSSSPAFGDLQDYYLFYLKAQTKKEDLLKMYGEEIACFDDVKKVFTNFISQSVNDQGVK
VCTGEYLGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKVNHFILVDGEH
>A3UVG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio splendidus (strain 12B01)|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A1A7WX38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Iconisemion striatum|TrEMBL
MVNQVQRVDGGWLSCKSDSSGASNSGGESSKESSRCSTPVLDADRSDRLRDKMRRRMESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEEEEGGFNYAV
DLVKHIRSEFEDYFDVCVAGYPTGHPEAGSYEDDLRHLKEKVDAGADFIITQLFFRADTF
FKFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKKEESVFEVFTCYIAAQPNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRV
NYHIVNVHGRNLTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWRVLDDMFELLDAPPEVLGDGMPG
DGSNGDAMPGDGSHGDGMPGDGSNGDAMPGDGSHGDGMPGDGSNGDGSHDNRTLHQ
>R3X106|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus caccae ATCC BAA-1240|TrEMBL
MRTDTLFKEKTVFSYEIFPPRRTAPIDTIYHTLDRLKGQQPDFISVTLGAGGAGANLSTA
DIAQKIQDEQFLPSVAHLPAVNFSKDEILVILEELKQKKVENILALRGDLLPEKEPKKDF
SYANDLVTFIQEQGDFNIIGACYPETHSDAASSVEDIRNLKRKVDCGTNQLITQLFFDNN
YFYTFKEKCDIAAIEVPIQAGIMPVVNKKQIERMVMMSNVTLPTKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVAQGADGIHLYTMNNPYVAQKIREATRSLFDAS
>A0A5Q3QN47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. SLB02|TrEMBL
MKVTEHIENAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
VMALRGDAMKDEQYFMPKAGGNDYAIDLVKQISLLNQGKYLHEVMDADNRANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFKFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDQCKNNAEIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASHLF
>A0A2E7HJF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MKSKGNLEARLTAGEFVITAETTPPDGASEESVMDKVGCLKGLVDAVNVTDGAGARAHMS
ALATCAIMAKNGIEPVLQFTVRDRNRLAIQGEMIGAPALGIHSILCLHGDSITNGDQPDA
KPVEDTDSRGLMAMAKHMRDTGTFPEPSNRKIDPAPGLLIGGAESPRDPDENFNTKGIEG
KLECGVDFFQTQFAYDIDVLKRYMAALDDRGITEKAHFIVGVGPVMSAKSARWMTENLFG
VNVPEHVIKRIEGADDERAEGRKVCAELVEQFKEIKGISGAHLMAPRGENAIAQTLSDYS
LRG
>A0A1I2Z2C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter insulae|TrEMBL
MKITDHIANSKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADSSFVPTKGGHCYATDLIEHIKNHNNGKFLHEDIDTFKSDFCIGVAGYP
EKHFEAPNLNADFKFLKKKVDMGAEFIVTQMFFDNQKYFDFVNKCRENGINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPDDLAEALSHAKNNAEAKEIGTAAMIKQCKELIEFGAPVLHF
YTMGRPEQTKQIARAIF
>S3II17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cedecea davisae DSM 4568|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWRSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELQTIAKDYWDNGIRHIVALRGD
LPPGSGKPELYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQSDLLNLKRKIEAGANRA
ITQFFFDVESYLRFRDRSVAAGIDVEIIPGILPVSNFRQAKKFADMTNVRIPAWMAQMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A2E6U3G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MTSISFEFFPPKSEAAAEKLWQSIGRLAPLRPDFVSVTYGAGGSTRDRTHQCVKRIIDET
DLKPAAHLTCVAASKAEVDSVVDDYAAAGVRHVVALRGDMPDMGSFQPHAEGYDGSVALV
AALAKRGGFDITVSAYPEKHPESASWDADIDLLKAKIDEGASRAITQFVFDTEAHLRFRD
RLSAAGITIPVIAGIMPTTNFAGTKRMAEACGAQVPQWLADAYEGLEGDADTRKHIAASV
AIDQCRKLIDEGFENFHFYTLNQADLTFAVCRILKLGAAAH
>A0A1F4QF71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division NC10 bacterium RBG_16_65_8|TrEMBL
MHIRDILKQNQPCFSFEFFPPRTREGAEQLYATMIDLVALQPSYVSVTYGAGGSTRELTH
GLIIRIHEHTGLTVVSHMTCVGAPKEEIGEILQEYQEHGIMNIMALRGDPPKGEDVFRQP
EGGFAHAADLVAFIKKRFPGMGVGVAGFPEGHPETPNRLMEMDHLKAKVDAGADYICTQL
FFDNRDFYDFCERCEIAGIAIPVIAGIMPVTSLKGMQRMAELALGARFPARLTKSLVRAK
DDEYVERVGIHWATEQVRDLIDQGVRGVHFYTLNRSKATLRIYETLGLKNVSRKAG
>A0A2E2CYK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTEVDQIVNFMSTCTLEVTPGGAAKIDDFRAVLRPDQIVYVTFLPGSNFRDTVVTVKKLK
DQGMRPVPHFAARSIPTKAFFEENLKMLTEETGVEEALLIGGGVDNPVGEFSESMEILRL
GLFEKYGIKHLGIAGHPEGSPDIKPAEVIRALLDKNAYAAQSPIDFYIATQFCFEAEPLI
QWDRQIRAEGNTLPIHIGIPGLATIKTLMKHAQACGIGNSMRFIAKQARNVAKLMSVSEP
DKLVRDLAHYKATDPSCGIIQAHLYPLGGLKKSSAWLHAIQDGKIELSKKGGFKTDYVVE
>A0A7L1LFN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Himantopus himantopus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVHGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKVLKGSYFLSPSPPLPAYLEFFTSSEIVT
ALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSW
KDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELL
N
>A0A4U0ZT88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus sp. IMCC35007|TrEMBL
MKRNFNDDISTPEKFVITLELVPGREFSGRTTDSIKEISNQAFVDGRISAVSITDNPGGN
PALSPDVLGRDILDKGMDVIVHFTCRDANRMGLESRALQLAHMGLKNILALTGDYSGQGF
GGRGTPVFDFDSVILTSMLNDLNRRLIKVGHDSVFVTGCAISPFKYTEAESWIQYKKLER
KIEEGASFAITQLGYDIDKYEELLFFMRDKELEVPTLASLYHLGRGAARVMNGGKVPGVH
VSSDLFNTIEKQWDIPEEGRAAAIERTARLGVVLKGIGYKGIHLGGIHGSFAVVERILDR
MEAIEHNWQEYRADFQEDKKDRFYLYHKDMDPKQKIPAKDPITLNLSESCHYLFLRAAHD
LFFDKAASLAPMYKKLSSSLDKTKRSWMLKRFVEDPFKKIVLSCEGCGDCGIQHVGFLCP
ESGCPKHTRNGACGGSKDGYCEVNTDKLCVWVRAYKRMKKYGETDKLTAEYVPPRLWELK
DTSSWVNFHLDRDHQRESK
>A0A7X7DG16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MTSPTIRELFAARRQPTLSLEFYPPKDARGFDLLGQSIERMRPVHPDFVTCTYGAGGSNR
EFSFAAWELLIRLGLTPVVAHLTCVGASRADLESQIHRIYDAGIRNIMALRGDPPRGETA
FTPAPDGLAHASDLVALIKSLHPDICCGVAGYPETHPEAVSPADDLRHLKEKIDAGADFV
NTQLFFHNDVYFQFMDAARAIGITAPILPGLMPVASPGQLDRAIGFSRATAPAALRDALQ
VPDPEAARTAGIQWMVNQINGLIAGGAPGIHLYILNQAHTVLDPRLTACLAHWRSPSTRH
ADL
>A0A7X6UVS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MATQQYKTGSQLEKLLVAGEFVVTAELGPPKSADLAALQAKIESLRGYADAVNVTDNQAA
TVRVASMAVARLLVEQGLEPVMQMTCRDRNRLALQADILGAYVLGIRNLLCLTGDHPRVG
NHPTAAAVYDLDALQLIQLTKNMRDRKIFANAEEIRNSAKEEILEPRMFIGAAANPFAEP
LELQIDILEKKIAAGADFIQTQCVYDIDRFQHWLEQVRARGLHQRVRILAGLTPLKSVGM
AKYMRDKVPGIILPPAFIARLERSSDPQAEGIQLCLEQIAQLRRVEGLAGIHLMAIGWEH
RVAEIIKPAGLWPRPAPR
>A0A7X8VPK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MISLWSIMAQQAKQIDMSFAGDERLGSAMMKGRFGYFLECDSPRSSQSFNASMALFKELG
LAFRQQEQLQGWLLSDRALSEQCHDPAPLAETLAKASDKPVIMAVSGRGSDLERCKSSLA
EGKATGRRDFLALSGDLSDLEDESGNKPYTDSVDILRSARSQGKDLRLGAVVNPFKYRPE
DQSLQYAKMLRKIHGGAQFLVAQAGWDMKKAQELQWFLQKMNLPIAVIARVCVFSQEEAK
ALAEGYKTGIHLPIPLACLIQQDAEKSREEFIEMQLLRAAWQILGYKKLGYAAVLLSGLH
KPKNWEKLLHYVEELEKLHPDYNTWLQLWSKQYGELNFVPGQDPHFLYHGLLQKNKRDFD
PEEDPVQGSALPKPAWQDRWRYWLGQKLDDPRKNAKAWDLLRRLCRLPKERLQELRPCFY
LNNQPCPKKLRWGACGNAGPDGLCENRRQPCFFHRVLHLAAHTNNYQDLESAAD
>A0A8C1WA87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MHSENMVVVIIKNIILFTKRNMVNQRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLD
ADRTDRLRDKMKRRIESGDRWFSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPA
GDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRG
DPIGKDWVEEDGGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKV
DAGAHFIITQLFFRAETFLKFVKDCRAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPE
EIMQVIEPIKDNDAAIRNYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGL
WAEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFG
ELTDYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDD
PLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTS
SENVTALLQVLKKYEPRVNYHIVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPV
SFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIED
MFTLLDSPQETQEEGSES
>A0A7X8VVA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MSDERKQINLSFSGDNRFASSMMQGRFLYFLEINSPLACQPAAAALALLKEKSRELAALP
QIFAFVVTDRLLSEDCHDPYLAAEAISAGSGKPVIISISGKGSNLSRVKGILADAKAQGL
RNFLAVSGDCQSQEQLAANPVHEHLDSLEILQAAGLFGPGLCLGATVNPFKYTPEDQCLQ
YTKMVRKLRAGASYLVTQAGWDMKKAQELQWFLQKREFAVMVAARVCLLSWEETQHLADG
YRPGIYFSVPLGSALMQDAQGTQEEFQERQLRRVAKQIVGYQKLGYGGVPLSGLR
>A0A7X7M0M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MMTEKELGDALRRALMVFDGAMGTEIYRRHVFTNRCYDELCLSEPGMIADIHRSYVAAGA
DVLTTNSFGANRLSLSAFGLGERVAAVNLAAARLAREAADQAGRPLLVAGSLGPLNTLGN
TSAERIQCLAEQAAALVAGGVDFLMFETLPSPEAAQEARAAVDSLKQPVAFVLSHSVPAD
GDVESAVRHRLTDWAAFPGPIPAAMGFNCCVGPDQMLSVVEVAVRCCELPLIIQPNAGTP
RNVDHRQLYLCSPEYITEYARRYVNLGARGVGGCCGTTPEHIREMARAIKPMTKSHVVAQ
RVDAEKTDAVPEMPLAERSRLGRKLAAKEWVTAVEMTPPRGWDTSQIVARARLCHDRGVD
TVNIPDGPRASPRMSPLITAAIILRQADIEPVLHVCCRDRNYLGLQADLLGSAAAGIRNL
LMVTGDPPKLGSYSFASGVFDTDSIGLVSLQKHLNRGLDLGGQKIIPPTAAVIGVGADPN
ALDFDREVRRLREKAAAGADYVTTQPVFDPEALFRFLDEIDDLGLPIIAGIWPLASLRNA
MFMKNEVPGVTVPDWVIERMTKASTSEEQLATGIAIAREAIDAIRDRVSGVQVSAPFGKV
EIALATLNAEC
>A0A8H8U6P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnellula subtilissima|TrEMBL
MHVSQMLSEAERSKQPKFSFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVNEALKETYKAGCTNILALRGDPPRENEK
WEATEGGFQYARILSSIFETQGCDDQDDLELLVDHLKEKVDAGATFIVTQMFYDVDNFLN
WVRKVRAKGITIPIVPGIMPINTYASFVRRCNHMNCSIPPKWMEALEEVKNDDAAVRNIG
TGLVAEMCRKILDSGLIHHLHFYTMNLAQATRMVLEDLKLTPSDERPLKQALPWRQSLGL
GRREEDVRPIFWKNRNKSYVARTQEWDEFPNGRWGDSRSPAFGELDAYGIGLKGTNEQNR
KLWGEPTSIKDVAEIFVRYLENGVDSLPWSEAPITSEADSIKADLIGLNKRGFLTVNSQP
AVDGVKSSDPVYGWGPANGYVYQKAYLELLVSPQLMNELIQRIERDPDLTFYAVNKAGEL
KTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDWAHCYSNLSPSRNL
IQNMMENWFLVNIVHNDFHQTHGLFRLFDELSVPSIDKPFEVEYKNGIDTNGVNGSKPGG
LEDITVTNGA
>A0A3R8UN46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. s199|TrEMBL
MTSANRPSISFEFFPTKTEAGHEKLLATARRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKQELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKARAGASSAITQYFFNADCY
FYFVERVRKLGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMDSIQA
FGTQVISEMCEKLLAGGAPGLHFYTLNQAEPSLAIWDNLGLSR
>A0A1G3ZKY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium GWF2_62_7|TrEMBL
MKLTDLAKSGKPLLTAEIFPPKGTNLARVLAKAKLLSPAIAAFNITDSQRAVMRLSALAI
SKVLRDAGYLPIYQLTCRDRNRIALQSDLLGAAALGIENVLLLSGDHPKHGDHPEAKPVF
DLDAAHLLDVARGLMAGKDMQGNALDGRPDFCLGAVVNPTAEPMEHQLFMLRKKVMLGAE
YFQTQVIYDVAVYRQFLAGVAALKLPAMPLVLPSVLLLKSAKMAERMAQVPGIRIPESVV
ARMQGAADPLAEGQKICAELIDELLGLAPGAHIMAINCEELIPDILARCKKL
>A0A515A0G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma sp. KCTC 42546|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFSREETEDFLIDLHYLGID
NALVLRGDPAKPFTTFKAKENGYTYASELVEQVANMNRGMYLHEEDTPLAPSNFCIGVAA
YPEKHFEAVNHDSDFHYLKQKIDKGADYIVTQMFFDNKKYLDFVDRCRQEGITVPIIPGL
KPLSTRKQIQILPKLFHLELPEDLVKMVEACENDQQARQVGVEWCIQQCRELVAAGAPVL
HFYTMGKADNVIKIAREIF
>A0A1F9BTQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_49_23|TrEMBL
MKLEESLKCKRFIVTSEIQPPIGTGIQDLVRNIDKIRGRIDALTVPELKIEGLVTDTMGT
CRALKDQRFDPILQTTCREKSRVDIQDHLIKACESGIENILTFTEDYRITGDSLQEIMFF
HVDSGKLFSVIENLHEGHDISGRELPVRPRFCVGSGIDSSWGKKVPDLELKEMEDLAGLG
TQYFLTTPIFDLDSFNQFMNRVGPIRIPVIAEIILVRSAEMGLFLNKHVKPGMVPNHIIE
KLAKAPDKEKASIEIVSDLVKGLKDLCQGVHFIPIGAEDRISKYLDAIKL
>A0A3N0D5D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. I6|TrEMBL
MALGTASTRTDRARTVREMLATDKTSYSFEFWAPKTEKGERNLWNALRRVEAVQPSFVSV
TYGAGGSTRAGTVKATQQIAADTTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPDGVRYAAELVRLIKESGDFCVGVAAFPETHPRSSDREADIGHFVD
KCRAGADYAITQMFFHVEDYLRLRDSVAEAGCETPIIPEIMPVTSVKQIERFARLSNASF
PAALEARIRAVADDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHEQS
>A0A1V3KRA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter heylii|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMENLLWESIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDASSEELKKIAQDYWDSGIRRIVALRGDEP
KGYDKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHIIT
QFFFDIDSYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPSWLTKAYDGL
DDDPTTRNLVAASVAMDMVKILSSEGVSDFHFYTLNRSELTYAICHMLGVRPSL
>A0A4R9LTT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira idonii|TrEMBL
MHISQVLGRKKTSISFEFFPPKNEEASEDLFKTIQDLSSMNPAYVSVTYGAGGSTRDLTH
DLVVKLQKQTGLTIVSHLTCVGATKDEIGEVLKRYNSSGIHNIMALRGDPPKGQTEFVKP
ENGFEYAGELVSYIKQNFPEMGIGVAGFPEGHPSTPNRLKEIEYLKWKVDQGADYICTQL
FFDNNDFYDFVERCEIAGIKIPIVAGVMPISSRKGMARMAELSLGSRFPAKLLRSLSRAE
DDSYAENVGIHWATEQVRGLLDHKVAGIHMYTLNKSKATRKIYESLGISNFELLN
>A0A1H6GLJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. NFR12|TrEMBL
MDTPAAKAPFKLSYEFFPPKSDEMQTQLWETVDALAAFKPEFVTMTYGAGGSTREPTLAA
VQRMINDAKLQTAAHLTCVDAAREEVKSVVEEYRAAGVRRIVALRGDSSAGVGAAYTPHP
DGFSDTADLVRMLVEYGDMDISVSAYPEMHPESPSMAADIDTLKRKADAGANRALTQFFF
DNEVFERYLEAVHAAGITIPIVPGIMPIQNLTQLKRFAGRCGATVPAFLDARFEGLDDKP
DDRAKVAADVAAEQIADLMRRGHDHFHLYTMNRVPLVSGVLERLGRHPDKDANVGNAA
>A0A4U0ZGF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus sp. IMCC35007|TrEMBL
MHISEIFNRNPIAYSYELFPPKSKEAAEQLFATISDLSPLELAYVSVTYGAGGSTRNLTH
DLVVRIQEETDLPVVSHLTCVGSTRDEIKSILDTYSASGIDNILALRGDPPQGQGPFEPV
DGGFRYAAELVEFIRKHQPQMGIGVAGFPEGHPETPNRLHEIDHLKAKVDAGADYICTQL
FFDNNEFYDFCERCELAGIRVPIVAGIAPITSVKLLKRMAEVSAGTRFPARLIKAMQRAE
NEEHQAKVGIHWATEQVRDLIDHNTKGIHLYTLNKSNATRQIYDSLGVTTTRGLV
>A0A318VUH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioalkalivibrio sp. ALE21|TrEMBL
MSNQERVFSVEFFPPKDEAGADRLAKARKRLGALKPEFYSVTFGAGGSTRDRTLETVKDI
INNDGIPAAPHVSCISSTKDELRDLLNAYRDIGVDRIVALRGDLPSGTKHSGGDFRYASE
LVEFVRAEFGNQFKIEVAAYPEFHPQAPSAEKDLDNFKTKVDAGADTAITQYFYNVDAYV
AFMERVQAMGITIPIIPGIMPITNYTQIVRFSEMCGAEIPRYIRKRMEAYGDDKDSIRKF
GIEQATRLTDDLLEKGAPGIHFYSMNQAGPTEQIWKDLDLDSRR
>A0A399Z905|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPIFTPGRRWQPAYSPFKKDAFANRVLENIEYAIKGPLFGCRMCGNCMLQETAFICPMEC
PKGLRNGPCGGSTPEHCYVDKTRPCIWYKIYERSFNMGREEKLLEVLPPLDWEKVGTETW
GDVFAEVRKMGVGKFFGGILFKSAQERYKTWDVVFTNIRQPDWWRGDAEYHAPAYSEPVS
DLERRLKAGEFVVACEIAPPLSMSTKKLIENINLVKPYVTAINFTDNASATPRMTSWACS
KIAIENGAEPVMQIAARDRTRASLQAEILGATALGVRNVLCVTGDSPVLAPHPRGRMDIN
DLDAVQMLWILRRMRDEGRYLDGREIKFPPRFFLGAAASPFASEPKFQALREHKKVNAGA
QFFQTNLVYDMERFEIWLNELAKRGILDKVYIMVGITPLKSLKMTQYMTQVPGVFIPPAI
LKRMEDADKAGAAQEEGAQIALELARKIKGYEAQGVHGLHIMPVGWEDIVPRIVKEAGLL
PDGIAEPAKVVV
>A0A7C5PYL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MKIRDLLDKNQPVFSFEFFPPKSDRGAETLFETIRELERLEPSFVSVTYGAGGSTRRKTL
EIVTRIKKETKVEVLAHLTGIGHTRDEIRHIVEKLVDAGIENVLALRGDLPREEGGPQGD
FPHASDLIRYIHELGAPLCVGAACYPEGHPEAEGRDQDLTHLKTKVHSGVDFLISQLFFD
NADFFVFEKRAREIGIELPILPGIMPITNYHQIQRFTQMCGAKIPPFLEEELEAVKDNLE
AVAGVGISYAIDQCRDLLRRKARGLHFYTLNKSPATRAILARLRREF
>A0A7C4IR49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSEFSESLARGVLVFDGAMGTELYRRHVFTNRCFDELCLSEPKLIAEIHQAYCDAGADVL
TTNTFGANRVALAQFGLAERQAEIIRAGVRLARQVAQAAPRRVFVVGSIGPLPQQPEYAS
QIDGMIAEQVSVLREEAVDAVIFETQPTRAALEQCARAMIRFPDVPYILSFVVDGEAESA
AGEPIERMLAPLAEGPQPVAWGINCGVGPDGLLLAVERAVKLTRLPLIVQPNAGMPKEVG
NRRIYLCSPEYLTTYALRYINLGVSAVGGCCGTTPDHIREMAKAVKPLSRAAVTRVALST
TDAPPPKQPAPLAERTQLGRRLVERQWITTVELVPPRGYDLKSTIEKSKLLQQRGVSAIN
IPDGPRASSRLSPIITAYRIQQEAGIEAILHFCCRDRNLIGMQADLLGCAACGVRNILFI
TGDPPKMGNYPNATGVFDTDSIGMAAVQRRLNCGLDLGSQPIDPPTQAVIGVGLDPSALD
LERELDRFRQKVEAGAEFAISQPVFDPDALLRFLDRVQHLGVPVIAGIWPLSSYRNALFM
RNEVPGVVVPDWVMERMASQETREGQLAMGIEIAREAVARVRDRVAGIQVSAPLGKVETA
LAVIEA
>A0A7J2HET4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrososphaeria archaeon|TrEMBL
MNVGRRRAGCPKRVLNGPCGGMRADGTCELGDARCVFADSQPSEIILDPGFKFRPKLKKR
KPFTRLLSKVWSEVVWVAEIPPSFEAAEKIQVLKDLSFSALSIPDNPLATLHLESSAFAA
YLKKALGCEVIVHLTCRDLNRLALKSRLLALQLSGVEHVLALTGDYPSIKSGSYSTPIFD
LDSIRLIYLARIMSDHGVDELGNPTSRSLRIQVGAGLNPYLPIEVEVSRALRKIEAGAEF
FITQLVFSLERIESLLKSLRREGVTIPVFLSFLLASGDRAQKVLKAIGVPAELPTNLNAL
TEAYLGILGRLRRLYGPVGAFISTLGKLEDLKIWDEAFKSLY
>A0A7C4ZRN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTYSFLQKLDARPLLCDGAMGTMIYSKGIPFEQCFDALNLTNPALIADIHRGYIDAGANV
IETNTFGANRLKLSEYGLAEQMADINRAGVHLARRVVDASFKEVFIAGSVGPLGPRLAPL
GRLSAAEARAAFEAQIAALVEAGVDLIVFDTFTDLFELVEAVQAARTVSADIPLVAQLTF
TDDGRTPLGHTPQKVAATLAGLPLDVIGVNCSVGPAGVLRVLQGLARALPAGMRLSAQPN
AGWPERVGGRIMYSSPPEYFGDYALAFVEAGARLVGGCCGTTPEHITHMRAALDDPARLA
PSLLRLPGDEPQAVHPADTLPPTRLARRLAEGQFVVSVEMSPPKGFSAERVLAGAATLQA
AGATVINVADSPRSRMRMSPWAVCHLIQTQLDMETVLHFPTRGRNILRVQGDLLAAHALD
VRNIFVVMGDPTTLGEYPQALDSYDVVPTGLIKLLKQGFNQGLDYGGEAIAQPTHFVIGC
AVNLNPPDPAREIKVLRQKIENGADFALTQPIYDAANLETFLARYEAEHGPLTLPLLAGV
LPLYNARHADFLHNEVPGINIPAGIRQRMRDAGEKGAQTGLAMARDLIRQLRPQVQGIYL
MPPFDRYDLAAEVIEGIEG
>A0A2E7RJP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MITPSESSDSGRQNLAQAITREVFVFDGAMGTQLNNRGLPFDRCFELASVENPEWVEAIH
KEFLDVGASGIHTNTFAANSFKLGRHGLEGRLQELLKAGVERAQVTATENTWVIGAVGPL
GVEIEPLGRLGRKEARAEFLKVIQVLVDSGVDGISFETFSSSTELVEAVSAAKEACSVPV
FAHLAVNREARTMYGTDLGAAVQRLESAGADVLGVNCSGGPRMILNAAREMIAATSLPVS
ARPNAGVPRQMDGRVFYENNPDYFARFARRFLQAGGRMLGGCCGTTAEHIRAMAQAARAV
GAQERGAPETPRVVSKEAERPQKPMPLRARSGFGRLLSDGACPVSVELVPPRTPNLDALR
QSARELKAAGADLINLPDGPRASARVSNMASATVLQKEAGVETLLHFCCRDRNLLGMQSD
LMGAEALGLRNLLVITGDPPYQGNYPDLTAVFDVDSIGLCNIIDNLNHGLDLGGNALDAQ
THFTVGAALNPTALDAERELERFAWKMEAGIDFAITQPIFDIESFESFLKALPENAPPIL
AGVWPLRSLRNAEFLASEVPGVEIPNSILEEMRRAHEAGTDQECGLEIARRTLESLHGKV
GGFQIAAPFNKVDAPISLLEALGEIR
>A0A7W6Q457|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter noctilucicola|TrEMBL
MALLNFRRKETPANEGADSPEVEAFLKDYSIEVMPRTAEKVEDFTALLPAGTRVYIAHIE
GTPIEDMVATAKRLNDDGFNVMPHFPARIIKDRATLTDWIARYQGEADVEQALLLAGGVV
TPHGDFSDSMQLMETGLFDKAGFKRLHVAGHPEGNRDIDTDGTRLKVDEALKWKNDFQTR
TDAEMAIATQFAFEAQPIIEWADSLKHAGITLPVHIGIAGPAKLQTLIKFAIACGVGPSL
KVLQKRAMDVTKLLLPYEPTDVVRELALHKAANPDFNVSHVHFFPLGGIKTNANWAIENG
GASAQPAKPAT
>A0A3G9JRI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Intestinibaculum porci|TrEMBL
MKIIDRLQEDKITLSFEVFPPKYSKNYDAVSQKALEIAKLHPDFMSVTYGAGGGTSEYTV
NIAKEIQQREGVDVLAHLTCVSSTKEKVHNMLEIFKANGIENIMALRGDLPDGETPHHYE
HASELIKEIKAFDPNFCIGGACYPEGHPEAHNKNVDIENLKKKIDAGCDFLTSQMFFDNA
IFYNFLFRAREAGIQVPIVAGIMPITRKEQVKRAIQLSGSSVPGRFVSMVDAFGDNEPAM
KQAGIIYATEQITDLIANGVKHIHVYTMNKPDVAKGIMDNLSEILK
>A0A3L7P1A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRLSQLFQKQPFVLSIEIFPPKTAEGDASLKRNLQTLTDYNPAFVSCTYGAGGSTRDRTA
YWCREILETFQRPAMAHFTCVGSTREELKDWLDTAAAAGIQNIMALRGDPPVGQESFRAV
EGGLKNANELVELIRETPPEMGIGVAGYPEKHVEASTMQEDLLNLKRKVDAGADAIFTQL
FFVNRNFLTFRDACEKSGITIPIVPGIMPVTDFARIKRITSMCGTEFPSDLATRLEAVQD
DAAAQFEIGVEHAIQQCEDLIKAGVPGVHFYALNKSEACQRILDAIQPSAVVH
>A0A3L7VJK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MPAIRAARLECLGSLRFPPRSFPELTPLRRHRNAVSIKDAYSSGRFGLSFELFPPKTPES
EQAMWQTVEELTTFDPAMITCTYGAGGSTRGTTLDVLKGVMARHALPVASHLTCVGSSVA
ELREYLREALQLGVAAIVALRGDPPKGETAFRPVDGGLRYASELVSLIRAEFPEFGIVVA
GYPETHQEAVSPEADLDNLKRKCDAGGDVIVTQLFYDNADFFRFRDECAARGIRAAIVPG
VMPVTNYTQVRRIASLCKARLPDSFTQSFEAAGADENAQFDAGVSFAARQVEELIEAGVP
GIHFYVLNKSPATIRVLDHVGMKRSVV
>A0A1B2N165|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas rhizophila|TrEMBL
MTALSFEFYPPKTDDQRAQLDRTAAKLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASELIAFI
RAEHGDAFHIEVGAYPETHPQSDDALRDLRYFKAKIDAGADAAITQYFFNADAYFHFVDA
VRKLGVQVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDADAVRAFGAEVV
AQLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLGR
>A0A2X4U5N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. arizonae|TrEMBL
MSFFHANQREALNQSLVEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3D3NPK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHIADILSQQKPTLSFEFFPPKTADASEALYQTIGELEALQPSFVSVTYGAGGSTRELTH
DLVVRIQKTTRLDPVPHLTCVCHSEGDIQAILERYAQAGVSNILALGGDPPRNLEGYERK
NDAFQHAADLVRFIKKFSDSGAHPDRRGFGIGVAGFPEGHPATPNRVLEMEHLKAKCDEG
ADYICTQLFFDNHDFLDFRDRCRLAGVHIPIIAGIMPITSAAGMRRMAELAAGARYPAKL
LRAIQRCGNDEEAVRRVGVHYATEQCLDLLGHGVDGIHFYTLNKSQATREIYASLGIRDS
ADVRKP
>A0A660V6W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MAEYLSRLHQLLARGEFVVTGECGPPKGADRSIVEKKASYLKGNVDAVNVTDCQTAVARM
SSLATCVILKELGLEPNLQMTCRDRNRIAITADIFGAYALGIRNILCLTGDHQKFGNHPE
AKGVYDLDSVGLIQLVRTLRDGKTINGEDVEGAPRMFIGAAENPFADPFEYRVTRLKKKI
NAGCQFVQTQCIYDIRRFREWMKRVVDAGLHEKCYILAGITPLKSVGMARYMQKMVPGMI
VPDELIERLKGVPKEKRADEGIRIAVEQIQQIREIEGVAGIHLMAIEWEERVPEIVKAAG
LLPRPQ
>A0A3S5Y8G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus hoagii (strain 103S)|TrEMBL
MTQTPSIVDRIRSSEASKSGRIPFSVEFSPPRDEAAEARLWRAVREFERLGPAFVSMTYG
AGGSTRDRTVRVTGQLADDTTLLPVAHLTAVGHSIDELRAMCGAYADRGISNILVLRGDP
PGDPLGDWVKHPDGVEYAEELVRLVRDMGDFHVGVASFPEGHYRAPDLDHDTKYLVQKLR
AGAEYSITQMFFDVEDYLRLRDRVVAYDREQGEKPIIPEIMPITSLRSARRSLELSGSSL
PPALEERLTRAAGDGPDENRAAVREIGIEVATEMSERLIAEGAPCLHFITLNFARATGEV
LANLGMSASASV
>A0A2D2DFC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia violaceinigra|TrEMBL
MATLDFSIEFYPPKTPDGADKLRVARAKLALLQPKYFSVTFGAGGSTQQGTLDTVVEILG
EGHDAAPHLSCVGASRESIRTILKQFQSHGIRRLVALRGDLPSGYGGAGELRYASELIEF
IRAETGDWFHIEVAAYPEVHPQARSPQDDLQNFARKVQAGANSAITQYFYNADAYFAFMD
QTRKLGIDIPVVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VSQLCERLLAGGAPGLHFYSMNQAVATTALWERLTAA
>A0A521ZAE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquabacterium sp|TrEMBL
MTTLTRLPISLEFFPPKTPEGVDKLAAVRQQLYPLKPEYCSVTYGAGGSTQDGTIQTVRA
ILSEGFDAAPHFSCIGATKASVREQLAQFKADGIKRLVALRGDLPSGYGGFGEFRYASEL
VAFIREETGQHFHIEVGVYPEMHPQARNPQADLQAYVTKVKAGADVALTQYFFNADAYFR
FVDDATKAGATIPVIPGIMPITNSTQLMRFSDACGAEIPRWIRTRLEGYGDDKASIQAFG
LDVVSELCEKLRQGGVPGLHFYTMNQSGPVLAIARRLGL
>A0A5C8DHP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIDHIKQAKETLISFEVLPPLKGKGIEALYKHLDPLMEFKPSFINVTYHRSEHIFKKR
ADGSFEKVVIRKRPGTESICAAIMNKYNVDTVPHLICGGFNINETEDALINLRYLGIDNV
LVLRGDAAKNETTFDAEPGGHRYASELLKQVTNLNAGIYLEEDLKSTQKTEFCIGVAGYP
EKHFEAPNMQTDLRYLKEKVDCGADYIVTQMFFDNEKFYAFVKSCREAGITVPIIPGLKP
IYNKKQLTVLPKTFHIDLPAELANEVLKCKTDLEVEEIGKEWLLAQSKDLKKNGVPVLHY
YTLGKPHMVADVVRQLL
>A0A2D5AVR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MQAARIDELYGQEKPVFSFEFFPPKDDDAAHRMMQTLDELGSMLEPDFVSVTYGAGGSTR
GRTVGLVKRIQEELGLTAMAHATCVGHSSDELGVVLDRLYEGGIRNVLALRGDPPAGETV
FRQAKGGFAHGSELVELVAQHGGFSVGGACYPESHPESVSAEADLKWTVHKVRSGARFLI
SQLFFDDAHYFRFVDRARSAGVEVPIVPGIMPITNVAQIERFTKMCGAGIPGELHERLTR
YQDDPSVVMAIGIEHAIRQCRRLLEGGAPGIHFYTLNKSHATRSILAAIKGV
>A0A1H2IB48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia westfalica|TrEMBL
MRIALYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFMPPRDAEGEARLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSIAELRALVGAYADQGIT
NILALRGDPPGDPLGEWIAHPEGVEYAEELVRLIGTLGDFHIGVASFPEGHHRAPDLEHD
TRNLVNKLRAGAEYSITQMFFDVEDYLRLRDRVQAADPEQGAKPIIPGIMPVTSLASIKR
MAELSGSVIPPNVVERFTKAAGDGPEEDRATVRAVGIDFATETAERLIAEGAPCLHFCSL
NFAKATSEVLGRLGVDVDAVLHVPA
>A0A3D3CVC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIDHIRQSTETAVSFEILPPLKGKTISSIYDHLDPLMEFRPAFINVTYHRSETMFKKK
SDGTFEKVEVRKRPGTVGICAAIMNHYKIDAVPHLICGGFGKRETEDALIDLHFLGVDNV
LVLRGDAPKNEAAFTPEPDGNQYALELLKQVVNLNHGIYLEEDIKNGSKTDFCIGVAGYP
EKHFESPNLATDLMYLKAKVDAGAEYVTTQMFFDNQKYFDFVKTCRENGIEVPIIPGLKP
ITNKKQLSLLPKVFHVDIPADLSNAVMKSKTDEDVEQIGTEWLLQQSRELKKAGVPVLHY
YTLGKPKVIWNVVKELV
>A0A0R1GRJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loigolactobacillus bifermentans DSM 20003|TrEMBL
MSLVDKFNEKTVFSFEVFPPRSTTSAEKLYQTLTDLQAIQPDFISVTLGAGGTDRYNDTV
GIADRIQNQLHIPAIAHIPGLYLNEQDVLSLLSELAAHGIHHVLALRGDAIPGKTPQGVF
QHADQLIQFIKANSDFEVLGACYPDTHKDAPDALHDIQNLKHKVDLGADHLISQLFFENQ
HFYNFREKALLAGVDVPIEAGIMPVTNKKQIERIAAVAGVPLPTKFARMLARYENNPEAL
RDAGIAYAIDQIADLVAQGVDGVHLYTMNNSEIANRIWSATASLFAASHKPATIK
>A0A3C0W0R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDIHAKKAAAGKPTISFEFFPFKTPEGEATFFGKTLPALMTARPDYASVTYGAGGS
TREKTLEIVEQIQNDFSLTTMAHLTCIKHTQAEIDAILEEANNRGIRNILALRGDPPPGE
DWSQTEGGFEFASELVTHIRGRGDFGVAVAGFPEGHIDCGERREVDWQHLVRKVGCGADM
VITQMFFDNADYFQLADFLRGAGVEAPLFPGIIPVANAGQIKKFSAMCGAKLPETFAARL
DELDDDAEAVREYGIEYATA
>A0A0Q0CBW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. porri|TrEMBL
MGSMSQDRRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVL
QLENEVKVPAAPHLSCVGDGKDDLRNLLAQYREAGIKRIVALRGDLPSGMGMASGELRHA
NDLVTFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADS
YFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQ
AFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A6I0EYW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heliorestis acidaminivorans|TrEMBL
MTRIVVELVPRSEEVLRLDLDTIKNHFPTVEGINIPELLRFEMRSWDACAIVKDYYQKAI
PHIRSIDINPQEPLPMAQRIRELEVKEVLVVTGDPPADMRSKVYPCNSIDMIKKFKQELP
DVKVYAAIDPYRKSIYKEADYIKRKIDAGADGFFTQPFFDLRLMEIYGELFQGTDVYWGL
SPVTSEKSVTYWETKNHVVFPRDFKPTLEWNVDFARKALQFARQQEGNIYFMPIRVDVKS
YLQGILD
>A0A6N7YZ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis pithecellobii|TrEMBL
MKSVVERLRGDTPVFSVEFFPPRDAADEAVLWRSIRELEMFDPAYMSITYGAGGSSRDGT
IRNIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGDWV
AHPQGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSPDLETDTRYLVRKFNAGADFGIAQ
LFFEAEDFLRLRDRVAAAGSDALLIPGVMPLTTPRTLKTTIKLSGARCPQWLLDRLEPLE
GDPKAFRAEGLDVVTELCERLIAEGVPDLHFYTFNRSKATREVVNRLGLVPART
>A0A8F8RMU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces anulatus|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A524E1F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MQPKKKKRGRKLKMAKRPAYSNLCKAVQEGQFVITGELEPKKILDLSEILHGAEEMKKTG
KIVAANVTDGPQGDAYMSSLVPSYLVQDKVGLEAVWQVTVRDRNRVALFGDVIAGAVLGL
KNILTLTGDHTALGDHKKGRAVYDIDSTQFCEMLSKMIDEGTDYEGNELEGGKIEMNYGC
VANPNSNPREPEILKVGRKVEQGIDFIQTQTAFDIDEAKAFLKDLEQFNVPVLLGIFPLK
SHGIAWYFDNFIPGVSVPKDLLKSLKTAEKENKGDKKGKYAAIDKINIEFFEPFIKEIKK
TTKAAGIHCMAVEYERLFDPLLKDF
>A0A847Y2H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolinea sp|TrEMBL
MPGFTPGRRWQPAYYAFHNDSLARKVLATLELMIKSPLFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGSTPEHCYVDNTRPCIWYKIYERSEKLGRSDRLLEVLPPLDWEKVGTEQW
WDLFELWKKKGGLKGTFKAIASKDRMAIYEQFFADYRQPDWWQGDNQPHPAPAHEPVSGL
EDKLVNGKFVVTAEVAPPISASAADLTKKVLMLKDYVDAVNFTDNPSATSRMSPLASSTI
CLQSGVEPVMQIAARDYNRMGIQSLILGAAALGIRNVLCLTGDHARLGPEPHSKMDIWDL
DSIQLIWLLRRMRDEGHFLDQREIKTPPPLFIGAASSPNASEQRFQVIRETKKANAGAQF
FQTNLIYDVDAFKTYLEMMDKAGILSRAFIMAGLTPIRSVKAAHMMNTVPGVKIPAALIE
RMEKSADAKEEGVQICLELIEKIKDLPINGIHFMAVGWESIVPRMVEEGGLQAKRQAA
>A0A7W9YIE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis mwathae|TrEMBL
MPTFADLIASSEPSRPVITAECPVPDGGGLADIAAHVARFAPYVDAVNATDNPAAHAHAS
SVAVAIALRQYGVEPVLQLVCRDKNRLALEADIVGAALHGVTTVSCLTGDDVTAGDEPEA
RRVFDLDAVQLIRMAAGLSRGRYLSGRTIDPAPPLLIGAVENPAAPPHAYRVRRALKKAA
AGARFLQLQICYHPDRLAEFTRIGAATGLTPKVALLPSVVLVKGARSLRYMNAHVPGVHV
PDEVIDRVAAASDPREAAYRLALDQSAHALSLPGVRGLHFIDFRHDDSLARICSDLGLPT
VRSAPEGNAMAV
>A0A8D0EWI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strix occidentalis caurina|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FIKDCQAIGITCPVIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCLPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A4Q9DUE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus thalictri|TrEMBL
MKPDLREALQSRILIGDGAMGTYLYQMGFPVGISYEELNLLKPEVIAEVHRRYYEAGARF
IETNTFSANREKLSKYGLENEVEAINRAGVELARKAVGDDAYVIGSIGSIRAGKRKNIRT
AKVKEDLKQQIDILIDAKVDGLLFESFYDLEELLLAVKIVRKTSMIPVICQFATEGTGTT
QDGFTLPDAFAKLQHAGADVIGFNCRSGPNGLLRSLEKVAGMQDIPFSIFPNAGIPDYVD
GQYRYAATPQYFAESALKFADLGARIIGGCCGTTPEHIAEMSKAIAGYVPSGTQAGDQPE
QAGFAPLRLIEKDAEHEQPVPAPKAEPTLVDLVKQRHTVIVELDPPRDLDIGKFMEGAKA
LKEVHVDALTMADNSLAVTRMSNLALGYLVKEQHDLRPLIHIACRDRNMIGTQSHMMGLH
ALGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKALKKKANFIV
GAAFNPNVKYLEKAVQRLERKVEAGADYIMTQPVYDPELIVKIHEATKHIDTPIFIGIMP
LASGNNAEYLHNEVPGIQLSDEVRARMAGLKGEEGRAMGVQIAKELLDVAMKYFNGIYFM
TPFLSYDMTVQLTRYVWEKANRRDFHLYPLTK
>A0A842VZ31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MSDDRVYSDLMRELKQGNFVITGELEPEVTTDIDPTVKEAVAMKPYVTAANVTDNPKATV
CLSSLAGSFLTQQKSGLEIVYQLTTRDMNRMALGAAVLGAGSLGLKNILALTGDHHQTGN
MPGAKPVYDYDSTHLIKLIREMVDNRSIEGIKFDDEAPDLKLHVGGAANPNTAMWGMGPE
IMHIRRKAAAGVEFLQTQVVYDIEVAAQFLKEVKDKTNVPVLLGIFPMKGYGIAKGFDEF
VPGVSVPKDLLSRFKEVKKGNWPNKKAKKDAYRKINIEFFTPMLKELKKRGLVAGCHIMA
VHYPKIFPPLVEALGLSPKE
>A0A8D9WE59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus M876|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A349W9V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MTAANAPSTGVPVSFEFFPPKTPEGAEKLRAVRQQLYALRPEFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREQLAQLRAMGVQRLVALRGDLPSGYGMGGEFHY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLKAYVTKVQAGADAAITQYFYSAD
AYFRFVEEARRLGAEVPVVPGIMPITSSTQLMRFSDASGAEIPRWIRLRLQAFGDDVASI
RAFGLDVVTGLCEQLLAAGVPALHFYTMNQSVATLEICRRLDLARAAT
>A0A1Y1RNA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia nasimurium|TrEMBL
MSTHIPALSYELFPPRSSASCESLLTTIDQLAPTNPDYVSVTYSGDRARKQKTLALLDHL
VHETRLTPLAHLTCVGHSAEELEAAVRRILAIGVRGFLALRGDLPPGSKQTPDIPFARSL
VDLIRRVETQDFAHLAAGRVAVGVAAYPSRHPESSSELQDIEILLSKERAGADFAITQVF
FETSRYESLVQRARAAGVTLPLIPGIMPVTSLRRLTTLCSLAGLPVPQRLAYDLETASGE
AERHHIGVEFGVRLLQESLDAGAPGIHFYTFNEHAAVLDVLEQVDLPRYKSRFENPLAEL
TYA
>A0A5C9CSI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MSPTHFPVSIEFYPPKTPEGVEKLRLVRQQLYALKPEFCSVTFGAGGSTQEGTFNTVRDI
LSEGMSAASHFSCIGATRERVRTQLATLKAMGVKRLVALRGDLPSGYGTGGEFQYASDLV
AFIRAEMPDDFHIEVAAYPETHPQAKSPESDLKAFAAKAQAGANSAITQYFYNSDAYFRF
VEEADALGVQIPVVPGIMPIGSSSQLMRFSDACGAEIPRWIRLRLQAFGDDIASIKAFGL
DVVTDLCEQLRAGGAPGLHFYSMNQSAATLEICKRLGI
>A0A562J035|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azomonas agilis|TrEMBL
MSTSERRYSFEFFPAKTEAGHEKLLATARQLAAYQPDFFSCTYGAGGSTRDRTLNTVLEL
DQQVKIPTAPHLSCIGDSKAELRSLLNTYQQGGIRRIVALRGDLPSGMGLASGELRFAND
LVAFIRAETGDHFHIEVAAYPEMHPQARHLEDDLVNFVRKAKAGADSAITQYFFNADCYF
YFVERVRKLGVEIPIVPGIMPITNYSKLARFSDSCGTEIPRWIRKQLEAYGDDMDSITAF
GEEVITRMCEQLLAGGAPGLHFYTLNQAEPSLALWRNLGLPR
>A0A421DAU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus turcosus|TrEMBL
MEKITDKIAALPPDENYFSLEFFPPKTQMGFANLTARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNRDFTFAVDLVRYIRKKYGDYFCLGVAAYPEGHPVDSYQDVQDPARDLPYL
VEKTQAGADFIMTQLTYDIDAYTKFEEMLRNHESGAFKTIPIIPGLMPIHSYKILTRTTK
LSHVRIPPQIMSKLDAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLNLEKT
VSFIIERCGLIPDDPEDSGAVADDDYATAPNGAQIRSLDRRRASSINSQPHNRVIVDRLQ
IPSDGSSRASTTHEVPATSAGMPAMPPDRNTTLQISEGNGALGREATWDDFPNGRWGDAR
SPAFGEIDGYGPSLHVSATVARRVWGYPVSREDISTLFRRHVSGDLYIVPWSEGGAEENS
SGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEF
FCPTKDFQTVLKPLFAKHGHEKLAWFATNAKGEFESSLPADPADADTIEMNPNNVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAYRIWDEWRRVYPRGTPTERFLDEAKNDVWLVCVV
GQDFGAGTENGSEEEQHETKWMWNVLINSQ
>A0A235ILW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. 'Peltigera membranacea cyanobiont' 213|TrEMBL
MHYTHSSTAFQRAVQAGEFLVTAEVAPPKGGDPTHMIQMAATLKGRVHAVNVTDGSRAVL
RMSSLMASVILSQNGIEPICQIACRDRNRISLQADLMGAHALGIRNILALTGDPVKAGDH
PDAKAVFDLEAVRLLQLIRKMNQGVDCNEKPLTDGALDLFVGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFDVLEKFMDTIAAGYKKPILAGIFLLKSAKNAQFINRCVPGVN
IPQHIIDRLAKAKDPFEEGIKIAAEQVQIARQLCQGVHMMAVKREDAIAPILDLAGIAPV
NQLVSM
>A0A146G6H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrimicrobium sacchariphilum|TrEMBL
MESLLETIVQLEAVAPDFVSVTCGAGGSTRELTYDLVVTLGRETTLNPVPHLTCVDHSRR
EIDGILERYARAGVGNILALRGDLPRDGRRSSGDFRHAADLVRAIREFQGHQDSRGFGIG
VAGFPEGHPDTPNRLLEMDYLKAKVDAGADYICTQLFFENRDFLDFRARCELSGIHVPVI
AGIMPVTSEVGLRRMAELAGGARFPARLLKDLSRANGDPDVVRRIGIHYATEQCVDLLHH
AVAGIHFYTLNQSAAIREILDNLGSLRSVAGV
>A0A7Y7PAJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTDHIANRKGRTLFTLELLPPLKGENIEAINQTIDPLVEFCPSFIDVTYHREEIIYKQ
REDGLLERKTIRKRPGTVGISAAIKYKYNIDVVPHIICGGFSREETENALIDLYFLGIDN
LLLLRGDNPAGEKTFKPEKDGNAFAIDLVKQVMDLNHGKYLEEEMINAIPTNFCIGVAGY
PEKHVEAPNMITDLAHLKEKVDAGANYIVTQMFFDNKKFFSFEKACRDAGITVPIIPGLK
PISVKSQLTALPKTFTIDLPEELVIEIEKCTDKEQIRQVGVEWAIHQSKELINFGVPVLH
FYTMGKSDNIRKIIKEVF
>A0A7X6HAW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter mobilis|TrEMBL
MTGKDVPALEEAAPVIPPGTRINVTFLGNEDLRMRVAAATAVRRLGFVPVPHISARRLAS
RQELEEFLDALATEAAPKDVFAVAGDPAKPLGPFEDSYALIRSGLLGNYGIEHVSISGYP
EGHPDISDATLWQALTDKYAALKDLGLESSIITQFGFDVDPVLSWLAELRQRGIWAPVRL
GVPGPAGVKRLLSYARRFGVASSAGIAHKYGFSLTNLLGTAGPDKFLHEFARRYEAAGHG
AVLLHFYTFGGLKATAEWVRDFRQAAAG
>A0A7K6DXA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grantiella picta|TrEMBL
MVNETQLSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITAHLQKAKRLGLKNIMALRGDPSGEEWEEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDELEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A350BLF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKQDFRQRLKKGPILCDGAMGTLLDLYEYAEQPREIHNATHPEIIERIHREYIEAGSEII
QTNTYGGNRYRLAEYHLADRVEELNRLGVEIARRAADDSVYVAGSVGPTGKLLQPIGKLK
LQEARDAFRQQIEVLLKAGVDLIMLETFVSLHELDEALAAAKELTKLPVVAQKTFPEDGA
ILSGSFPVEVAEHLLSRGADVVGANCTVGPQRMFSIITSMHKEGIYLSAQPAAGIPTLLD
GRALYHTSPEYLAQYARELLQAGVTIVGACCGSTPAHLREIKKVLDEFRSSPAGATRERT
PQIQVRERSGPADAADVAPDSRSRFARNLGTKFLTSVELDVPRGLDMSSVLDGARYLHRH
GIDAINITDGARARLRISSVALSHMLQRDVGIEAMMHMTTRDRNMIGVQAELLGAHALGI
RNVLFITGDPTNIGDYPQATSVFDIDSSGLIRSARAMNEGRDLMGNAIGQSTSFLIACAV
NAMADNMDAEMAKLEKKIEAGVHVIYTQPIYEMRTLESLLKRIDRWKVPIMLGVLPLRGF
KHAEFLHNEIPGMVIPERIREQFRSAGPKAQAVGIEISVKFLTEAKSLVAGAYIMPPFKK
YEIVPEILAASGVKPS
>A0A6A0QZA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MVLDKLKNNKNTLFSFEILPPLKGKSIQSIYDGIDPLIEFNPAFVNVTYHREEFVYKKRE
KGYLEKISIKKRPGTVGICAAIQNKYDLEAIPHLICGGFTKEETENALIDLNFLGINNVL
ALRGDPIKTEPHFIPEPGGNKYAVDLVKQIVELNHGKYMDENLEHASPTNFSIGVAGYPE
KHFEAPNMKADIKRLKEKIDAGADYIVTQLFYDNQKFFKFVEICRKEGINVPIIPGIKPI
ENLRHISFLPKFFNIDLPTDLTDELDKCQTNEAVFEVGTAWAKQQSKELIEFGAPCIHYY
TMGKSKAVKKIASQIF
>A0A5N7TWB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp|TrEMBL
MLVEYLTSLHEIYPVKYEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIDKVLHFSGK
ARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKNNYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDRVYLRCALQILICKH
LGYAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVTSGKEFSPEIARFSL
QPTSKQLIKYRQLHVMHEAMFGSKIAKGLGRFIFKASFWENALVAKVLLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVEQT
EILKDKLIPTVPLETRGTSSWKNWYLGAEA
>A0A7G8J0J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. MIT S9220|TrEMBL
MGSALQRSLEAGAVTVTAEVMPPRGGDPSHTLAMANLLRDWVQAINVTDGSRAVMRMSSL
AVCRLLLDAGLEPVLQMAGRDRNRIGIQADLLGAHALGIRNLLCLTGDSVKAGDQPSVRP
VHELESVRLLQQVSSFNRGEDPVKESLPDGPTALFAGAAADPHCASWSGLKRRLERKREA
GARFVQTQMVMDPQVLERFCRDMAAPMELPVLAGVFLLKSARNASFINQKVPGANIPDSL
IARLDAASDPAAEGIAIAAEQVRQFAGIAQGVHVMAVRAEERIPEVLERAGLSSQQL
>A0A839XR38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella sediminis|TrEMBL
MRRRRESGNAPVPTAAPAGVLARPRFEVLPLRGVLEETGTLPEHTVVTVTASPRRGTEAT
VELCEKLAAQRLRPVPHLAARQLTGRSELIDVLDRLAGAGVDDVFVVGGDTPEPAGPYPD
GAALLREMADLGRLPAEVGVPSYPEGHPSIDDATLWASLRSKQDLATYTVTQLCFDLAAI
REFLRQAGEHGITLPVVIGVAGAVDVTTLARVGSRIGVGDSLRFLTSHRSIVGRLLRPRR
GRDAVLRGVVDLAARPGEPTPAGVHCYTFNKVRATARMIADLSAATGGTGGPASGPGGEG
>A0A7D5SA98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHIRKAEGKPLFSFEILPPVKGKSMDSIFKVLDPXMEFNPAFINVTYHRSEQVYRK
RTDGSFDLIDMRKRPGTVGICAALMNHYKVDAVPHLICGGFSKDETENALIDLNFLGIDN
VLALRGDPPKNEKYYQPHPHGHHYAIDLVKQIEKLNKGIYLEEDITDGGKTDFCVGVAGY
PEKHYESPNPDXDLMYLKNKMEAGADYITTQMFXDNSKYHRFVESCRAMGIKAPVIPGLK
PITSKKQLSAIPSIXHVDIPSDLAVALMQCKNEQDAEKVGTEWLIHQAKDLIQSGAPVIH
FYTLGKPQVIYQVMKAIV
>A0A670JLT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Podarcis muralis|TrEMBL
GYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVTMCRELLDSGLVHGLHF
YTLNREVATVEVLKHLGLWKEDPRRSLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRDELLKMWGEELTSEESVFEVFRCYIA
GEPNKEGHKVTCLPWNDEPLAPETNLMKEELAKVNRRGILTINSQPNINGKPSTDPIVGW
GPDGGYVFQKAYLEFFTSSENVRALQTVLKNYGQRVNYHIVNVKGENITNAHEMQPNAVT
WGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEEESPSRMILQYMHDNYYLVN
LVDNDFPLDSCLWQVLEDMHTLLNC
>E4S7K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldicellulosiruptor kristjanssonii (strain ATCC 700853 / DSM 12137 / I77R1B)|TrEMBL
MKKNFREFLKEQSTVIFDGAMGTELLNRGFSLDFPLEWANVTRPELVKQIHTDYILAGAS
SIETNTFGANECKLKVFGFENEVERINRSAVRIAKETADDKVYVIGSVGPLGKPVGSGFE
IDDRRAKEVYKRQLYFLLDEGVDAIIFETAASTHEVQIAIEALKDLNDEIPYIIQFSFTK
DLSTIYGEDIYRVIEFLKSTDADVVGLNCGNGPQKTLEALKIFSQNLKGPFSVQPNAGYP
QLVQGRLVYSTSAKYFASFVPEYIKLGAKVVGGGCGTTPEHIKAIKEKVKEFLPSIEVEV
VERKEEQKAVLKDTPSELSQKLGKKFIFTVEISPPKGIELEKTKEGVKLLKEAGADTVNI
ADSPMARVRISPIALAHILKEELGMESILHFTCRDRNLISLQSELLGAAALGVKNVLALT
GDPPSIGDHPQAKPVFDVNSEGLVLILSRLNNGTDYMGNPIGKATNFTIGVALNLNADDL
GKEIEKLKHKIENGAHFIETQPIYEPETLERFFEKVDFKLPPILGGILPLRSSRHAEFLH
NEVPGITIPDKIRERMRSSKEPAKEGVEIACEIVEKIKHMVSGIYIMPPFEKYEMAAEII
KMFK
>A0A661Y561|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MSTRLIELLKNPEKTHFSFELLPPLKGQNIEAIYNAIDPLMEFKPPYINITYHQEEVVYR
NVGNNLLEKRIIWKRPGTVAISAAIKSKYKVAVIPHMICGGFTREETENALLDLNFLGIR
NILAVRGDPQSDSRNFIPEEGGHQHTMGLIEQINGLNKGIYLDEELEKKTPTDFTVGIAG
YPEKHPEAPNMRSDIHFLKKKIKAGAEFIVTQMFFDNEKFFKFVKLCRDADINVPIIPGI
KPLATYRQLNFLSKTFNIDIPEALVKEVIKCKDNTQVRQVGVEWTIQQSKELVSADIPAV
HYYTMGKPDNIQQIAKAVF
>A0A658BNQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonadales bacterium|TrEMBL
MNSSLLTPPSSPVLSFEFFPPKTPEGMEKLRATRQQLAQLKPEFFSVTFGAGGSTRDRTL
ETVIEIQHEGHKAAPHLSCIGSTRENIRAILDEYKSHGIRHIVALRGDLPSGTQDVGEFR
YANELVAFIRQETGDYFHIEVAAYPEYHPQAPSAQADLANFKRKVDAGANAAITQYFYNA
DAYFNFRDECDAMGIDIPIVPGIMPVSNFSQLARFSDACGAEIPRWLRLKMQGYGDDTAS
IRACGLDVVTAMCDRLLQGGAPGLHFYTLNQAGLITTIWQRLGL
>A0A0Q4KAT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf29|TrEMBL
MTPTISDLEEARRALDAPLFADLAGDCAVSFEFFPPKTEKMEAALWETVRALEPLAPKFV
SVTYGAGGSTRERTHATVARIARETSMPAAAHLTCVEASRAEIDQVAQEYWTAGVRHIVA
LRGDPPTMGQKFVAHPEGYENAAALVAGLQKLHPFEISVAAYPECHPDSEHQAADLDNLK
RKIDAGATRAITQFFFTPEAFFRFRDAAAAAGIHADLVPGILPVSNVAQVRKFAGLCGAS
IPAWMDRLFEGLDDHPGARALVAATVAAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPKAKPVAVAA
>A0A2T6E8N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharospirillum sp. MSK14-1|TrEMBL
MPSSVPVSFEFFPPRTEAGYEKLFSEHNALKAANPEFFSVTYGAGGSTQERTIQTVIDLN
QRGVPSAPHLSCIGTTEATVVELLDRYREAGIRRIVALRGDLPSGMGGTGGDFRHASDLV
QFIRTHYNDTFTLEVAAYPEMHPQAPNFDADIQNFITKAKAGADRAITQYFYNADAYRHF
VREVRARGCDIDIVPGIMPITNVSSLIRFSDACGADIPRWLRKQLEACGDDSKRIQAIGQ
TVVTNLCRELLDSGAPGLHFYTLNRAEPSLAILDRLG
>A0A366HSP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseimicrobium gellanilyticum|TrEMBL
MHICDIFNERKPTFSFEFFPPKTPEGAETLFEAIRELEVYKPAFVSVTYGAGGTTRDLTH
DLVVRIKQTTSLDPVPHLTCVCHNEEDIASILERYAQAGVSNILALGGDPPRNLPNYEKA
KDAFQHASDLVRFIRRFGSNGAHPDGRGFGIGVAGFPEGHPSTPNRLMEMDYLKAKVDAG
ADYICTQLFFDNRDFFDFRDRCRLAGIHVPILAGIMPITSAGGMKRMAELAGGARFPAKL
LRAIARCGNDEDAVQRVGVHYATEQCADLLDHQVDGIHFYTLNKSKATREIYAELGLKDS
HSFQSHPRPS
>A0A1G9QQW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium taihuense|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYVYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHGSAMELVHQINDLGRGKYLHNQDEVCDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVQKAREMGITVPIIPGI
KPIATKKHLKVLPQIFKIDLPEELISEVENAKNNEAVKQIGIEWAIAQCRELLKFEVPVL
HFYSMGKSDNIKKVAGALF
>A0A5P2M451|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter werkmanii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A0W1II18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. A083|TrEMBL
MTTSLDALAEARRAAASPLFANLEGDIGVSFEFFPPKSEKMEAQLWDTFRTLEPLAPRFV
SVTYGAGGSTRERTHATVARIASESAVPPAAHLTCVEASRAEIEEVARAYWDAGVRHIVA
LRGDVPGGGAYQAHPDGFANAVELVAGLKRIAPFDISVAAYPEVHPDADCPQADLDNLKR
KLDAGATRAITQFFFSPEAFLRFRDAAAAAGIDAPIVPGILPVSNVSQTRRMADMCGTAI
PAWMIALFEGLDDLPAARQLVAATVAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHMLG
LRPVAPAKDKAA
>A0A4P5T9D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTDYLKNAGNNTLISFEVLPPLKGSGMQDIFNLLDPLMEFKPPFIDVTYHREEYIYKK
QDSGYYEKTAIRKRPGTVGICAAIMHRYDVDAVPHLICGGFNREDTENALIDLNFLEINN
VLALRGDALQFDSKFVPEPGGNAYALDLVKQVDDMNHGRYLDENIENGQKTDFCIGIAGY
PEKHFEAPNMESDLAFIKKKVEAGADYIVTQMFFDNKKYFEYVESCRNAGINIPIVPGLK
PLTKMYQLSSIPRHFYINLPEDLVAAFLSAKTMEAKRQVGIEWCVAQSRELKAAGVPCLH
YYTMGDVDTIKKIAESVF
>W4K050|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heterobasidion irregulare (strain TC 32-1)|TrEMBL
MKISKKIEQAAKDDKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSELVKTCQSLIGIETCMHLTCTNMPKEKVDIALREAKQHGCENVLALRGDPPTGKDE
WEAVEGGFAHAIDLVRHIRQVYGDHFDIAVAGFPQTQILPAEERALEMKYLKEKVDAGVS
FIFTQMFYDVDIFIEWVKSVREAGITIPIVPGIMPIQTWNGFQRATSLAKTKIPQSFLDA
LEPYKNDDEKVREIGTKLVADLCRRILKEPIGIRGLHFYTMNLERGTKMLLEELNFVPRV
ETIKPLPWRQSLTPTRRQETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALALWGRPATFTDIAHLFELFCKKELSALPWSDQAVSTETSVIAEQLA
KINGHGFLTINSQPAVNGARSDDKVFGWGPSNGYVYQKAYLEFFVSPELLAVLLPHIERD
HSITYYVINKRGDLNTNTTSEGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGQQ
WAKLYETDSASRNLITNLMDKLLLVNVVHNDFTKPEAIFEPFLKAGAEFAAASAATSAAQ
PEGLPN
>A0A2D7XL76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MTSVSFEFFPPKSAETEAKLWDVVNDLSVIGPDFVSITYGAGGSTRDRTHKCVKHIVTKT
DLKPAAHLTCVAASKSEVDEVIEDYANAGVKHIVALRGDMPDMEAFSPHPNGYSGSVKLV
ESLAKRGGFDITVSAYPEKHPESDNMQTDIDLLKAKIDAGATRAITQFVFDTEQYYRFRD
LLAYNQITIPVIPGIMPTTNFKGVLRMSEACGASVPEWMKNKFDGLDEDLESRRALAIEI
AIDQCQDLINSGFGNLHFYTLNQATVTKAVCNALSLDKVVGHS
>A0A2A4R263|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MKEIQMTNKIAASIEVSPKQAVENADLPGLFPAKTRVYITDIGTDSAETLTAGAKRVSEL
GYTAVPHFASRRLTTKAALEERIKMMTGEAGITDVLVIGGGLEKQAGDFSSTMEVLETGF
FDKYGITHMGVAGHPEGSPDFSDEVALEALRLKKSFANRSDIELRIVTQFGFDASGFISW
ADSLAEHNIDLPVHLGVAGPAKITTLIKFAAMCGVGNSISFLKSRGSAIMSMVAGFDPNE
IVDPIEEHIKTHGEASPIKQIHVFPFGGVKKSAQWLEERGTWDIKTSLYANTNSD
>A0A1I5F077|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. OK281|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGISFEFFPPKSEKMDAQLWDAIRTLEPLQPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPVDKVAAA
>A0A2W5PDH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium zucineum|TrEMBL
MSPADTAPPTALGPVARAGAGQGPRPRVSFEFSPPKGPKSEESLWEAIRRLEPLNPEFVS
VTYGAGGSTRERTHRTVVRILKETTLKPAAHLTCVEASRGEVDEVIQDYWDAGIRHIVAL
RGDPPGSLGGAYTPRADGYQNATELTAGIKAIAPFDVSVGVYPQIHPESPSVDHDIEVLK
AKVDAGATRAISNFFFDIDGYLRFVERIRKAGITVPILPGIMPVSSFSGLANMAGRIGVE
IPGWLATHFEGLDEDPETRKLVAASVAAEMCARLAEEGFSDFHFYTLNRADLVYAICRVL
GIRETPPAQPKEAAA
>A0A7G8DSJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. BIOS-U3-1|TrEMBL
MGSALQRSLEAGAVTVTAEVMPPRGGDPSHTLAMANLLRHWVQAINVTDGSRAVMRMSSL
AVCRLLLDAGLEPVLQMAGRDRNRIGIQADLLGAHALGIRNLLCLTGDSVKAGDQPSARP
VHEMESVRLLQQVSAFNRGEDPVKENLPDGPTTLFAGAAADPHCASWSGLKRRLERKREA
GARFVQTQMVMDPGVLERFCRDMAAPMELPVLAGVFLLKSARNASFINQKVPGANIPDRL
IARLDEADDPAAEGIAIAAEQVRQFAGIAQGVHVMAVKAEERIPEVLERAGLSSRPS
>A0A485NTN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lynx pardinus|TrEMBL
MVNEPRGDGGPTSRSEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDGTGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDRVGEQWEEEEGGFSYAADLVRH
IRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPR
>A0A853CYF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia shinshuensis|TrEMBL
MSDTAVELSGEHVIAFLDDYSIEMTGKDVPGLDEARDALPHGTRVNVTYLGAEDLEQRVT
AARAVREHGLLPVPHIAARRLTSEQELARFLDRLAEVQAIDKVFVIGGDPSEAAGPYPDA
LTLIRSGVLERHGVREVGIAGYPEGHPDIPNSALWEHLEAKVETLRERGLQTVIVTQFGF
DTEPVVAWIRELRSRGIDAPVRVGVPGPAGVKRLLGFARRFGIGANAMIVKKYGFSLTNL
LGTAGPDRFVASLATQLTEQGLAKDVKMHLYAFGGLRATAEWAQRFTLEGARR
>A0A7W4J018|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconacetobacter asukensis|TrEMBL
MSLSQPPGPGLSFEFFPPKTPKMAEALRQTASVLAPLGPRFISVTYGAGGSTRDRTLQTV
AELVRETNVPVAGHLTCVDATRAEVDAVARAYWDAGVRHIVALRGDPSELGAPFVAHPDG
YAGAVELVAGLRRIAPFEISVAAYPETHPAAISPAADLDHLKAKIDAGATRALTQFFFEA
ETFLRFRDRATAAGITTEIVPGILPVANIAQAYRFAEMCGAHVPDWMRRLFDGLDDHPGA
RAMVTTTVTAELCRQLHDHGVTDLHVYTLNRPDAALALHRLLHAGSTP
>A0A8F7KAS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain ATCC 19606 / DSM 30007 / JCM 6841 / CCUG 19606 / CIP 70.34 / NBRC 109757 / NCIMB 12457 / NCTC 12156 / 81)|TrEMBL
MTLADRVHSDHDIAPLEASKSYPDSIDKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLL
TGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLH
KKIKAGADFIITQLGYDIEALKQTKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGI
VITPHMLKVLAGEKQAGHTDRVYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIE
QYRHLNLKALEELWSSLWQVKTGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKI
AKGVGRFIFKASFWENSVVAKALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGL
ANGPCGGTNLDRCEFGDRECIHSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWY
LATEA
>A0A026X227|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ooceraea biroi|TrEMBL
MRNLIVDEDTCRRSDVARRDSAGGSSSDNVRTARRRCEIVDLRRALQGKISSNEIFCGLE
IVSASRPSGFYQRLLEEMGKYSPLFYALTWHEEAPADTENYLPLNLLENFPSNTLLHLAA
KSFKRDEVIRISRKALALGTINVFALRGDSLSEDGDFKHAADLVAFIREQFGGTFCICVA
GYPQMHPESPSRELDLLYLKAKVDAGADFIITQICFESQAIIDFVNDCRKIGIRVPIVLG
IFVPMSYECLERMASICKLDVPVKIKDDLSRVRDNDEAVTKFAVDLAMQIMTDVIRSGVT
RGFHLFTLNRLPLVAEIYRRIEFLKTEFGN
>A0A1G9RXX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas muralis|TrEMBL
MNDINRAALTAALESSARLAIRFELLPISGLRKAARELPEGAVVTVTCSPRHGLERTLEA
TEWLVGEGFRVVPHLAARLVRNHGHLKRLLQRVEALGIEDVFVVGGDVPRAVGDYPHGLA
LLEAMAGLALRPVRIGVPAYPEGHHRIEAPCLQQDLEAKAALADYAVTQLCFEARPLLDW
RDWQARLGLRLPVHAGVPGVIERKRLLGIALRLGIGSSVQALRRQSGRMSRLLGPLAYRP
DALVDELGARLGDSVSGFAGLHVYTFNQVAATRNWLEELGDRQLTSSPEAKRVPCK
>A0A259U885|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa silvacetica DSM 10669|TrEMBL
MLKDKLGKSFVYTTELGGINGTDIETSIAKVKEYSGLDALNIHDCPNARLRMNSVMAAAV
ITKATGMETIPHFTCRDRSLLGTQADLLGAHALGIRYILPTTGDGPQHGPYQSTAVYDYN
SAKLIELIKSFNQGKDANGEVFQGQTQFTVAATATPGAVNLDAEMANMVKKANAGADFFQ
TQPVYDAEQTLCFLAKAKTLGKPILLGLMPLKSPKMAEFVNKNVAGITIPANILAEMQQG
KTGFEVACEFIRQIYQQIDGLHIMGMGDVAVTNKLITFTRELQSQR
>A0A522AC87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MRTRVPVSFEFFPPKTPEGAAKLQHTRAALTAFGPDFFSVTYGAGGSTRANTLATVLAIH
DAGCPVAPHLSFGGDDADGVLKLVDQYRAAGIHRLVALRGDLPSGMGGAAQLVHANELVA
LIRRHSGDHFRIHVAAYPEIHPEARGYGDDIHWLGQKFAAGADAAITQYFYNADAYFQLL
DACARAGIDRPIVPGIMPITHYQNLVRFSASCGAE
>R7J9L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium sp. CAG:439|TrEMBL
MKLREIYSSGKTVISFEVFPPKSDIDKLLQEIKILEKYNPAFISLTYGAGGSENKSFDLL
KHIKSTGVNVMPHFTCISSSKESIEADMKKLGDIGIENILALRGDIPENNELCRNDFRYA
NELVSFIKAKTNFSTGVAGYPEGHIESPDLKTDIENLKKKVDAGADAIFTQLFFDNDLFF
DYVNRVRNAGIEIPVIAGIMPVISEKQVNRMISMANISVPDKLKQNIQKFKGKDLIAFGI
EFASSQCSALIKEGVKGLHFFTLNKSYSANRILDNIKEEI
>A0A3D0RXB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp|TrEMBL
MVRLLSQTRYEVLPTASIEDQVLEHVDRAEAVTVTASPGKGLEATLDLTERLTKHGYTAV
PHLAARMVRDRIELEEICARLTSQGIDRIFVPGGDADPPGDYPDALSLLEELKAIGSPFG
HIGITGYPESHPTISDDLTIQSMWDKRRYATHVVSNLTFDPEVLTTWVGRMRKRGITMPL
LLGIPGPVDRTKLLSMATKIGVGESTRFLAKHKGTFARLAAPGGFTGEKFLEKVAPSLAP
AEMFVEGLHVFTFNQVAATVAWRRDLLDQLTAKA
>A0A4R7TEY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2575|TrEMBL
MGDGFEVVCEVEPPTRPDLRKVRHQIGVMSPIADAFLIPDNHIGRATVSSVAVANEVQAM
GARGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDEPTAGARTSQLTVRTMIEEAR
ATSFPGIAPFQVGAATRLRPIPAWKAEADFLYVQVSYSLDDLLRWRDTVTADIPIYAGVM
VLASAKMAHNLAALPQLTIPDHLIAAVEQDPDAGVEAACDHILQIKESGAFDGVHLVPVS
RYRQVAARLEREL
>A0A522A5P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
LIRRHSGDHFRIHVAAYPEIHPEARGYGDDIHWLGEKFAAGADAAITQYFYNADAYFQLL
DACARAGIDRPIVPGIMPITHYQNLVRFSASCGAEIPRWLQHSLADWGEDAAGLREFGVE
VVARLCERLIAGGAPGLHFYTLNQAEAAADILRSIGFAAAH
>A0A1F9ALS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_61_14|TrEMBL
MTERAGSRLERVLAAGHFAVTVEVGPPRGPNAAAVRRKAELLSGVADAYNVTDNQTAVVR
MSSIAGARLLLEAGLEPVMQMTVRDRNRIALQSDLLGASALGIKNCLCLSGDHQQASASG
KLNGHPGAKHVYDVDSIQLLAILKGLGEQVQESGDPIAEPARFFIGAAWSPLAPPEAFRV
LRLAKKVAAGADFIQTQAVYDVPRFAAQVAKAREMGLCDQIAILAGIIVPRSARMLQYLN
EKVPGVEVPEELIRRLRAAVNPASEGKMIAQELIEAVRVIPGIRGVHLQAIENEEVLPEI
ISAAELLPRPVLNIGA
>A0A832K1B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
YAAAPEYFRDYTLEFWKAGANVIGGCCGTTPEHIAAMRKTLDSAPAIAVEPVSRVAVSRS
DTEPAEAPSELAQKLAGGKFVFAVEMDPPRGLATQKLVAAASLLKEAGADVIDVADSPLA
RMRMSAWAVCEVVQRKVGIETTLHFPTRGRNLLRVQGDLLAAHALGIRNVFVVMGDPTSI
GDYPEAADNYDLVPSGLIKLIKQGFNTGVDHSGTSIGQPTSFFAGSALNLCSPEPETEIK
NLKRKLKAGADFFLTQPIYDPEKAKAFLDKFAEANGAPLEKPVLVGILPLVSVKHANFLH
NEVPGIMIPEEIRQRMADAGEQASREGVKIAVELIQQIKEWGQGVYIMPQFHRYDLVAEI
IESSK
>A0A2G7HDK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium combesii|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELEENNIENILALRGDMPNDKNIIGE
YNYAFELIEKIKENNNFGVSGACYPEGHIECESLKQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLSKTQQKNINVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A8J7P776|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Obscuribacter phosphatis|TrEMBL
MHPFLETLAKRPLLADGGIGTLLYSRGTSGEASFEHLNLTRQETVQQVHVDYINAGAEII
ETNSFSGNRFKLANHGLDAEVWKINVWSAKVARNAREIAGQPVFVAGSVGPTGKLLPPLG
DTDRDSICDAFKEQMEALLAGGVDLFLIETMSSLEETALAVKAARNVSKLPVIAQLSFSV
EGHTLLGAVPEDIVKLLQELGDDMPDVIGINCGAGPGPVFDSFLRLTTAIKSLKIAPNRL
TFSCLPNAGQPSLMGGRPMFMSKPKYCASYIEPYLRAGARIVGGCCGTTPDHIKAMRQAL
DQYIAQNEEHSSKDESKETKETETKSVGSLVTVLYNPEAIENTVEMASQKENAKISLAER
LRRIKQKTEQDFYISVELDPPKGAGTKKITQAAELLYAAGADAINVGDSPMARVRMSSLA
TCQLLSQRIGVDTIIHFTTRDRNLMGMQADLIGCQALGLHNILALTGDPPALGNYAHATA
VYDVDSIGLIKIIKQLNQGQDIAGNTIGAPLSLSIGCALNPTAQNRALELERIKRKIEAG
ADFIMTQPIYRKSDLADFIEDMGGCPVPLLVGIMPLHSSKHAEYLHNEVPGITIPKHIRE
EMAKAGDDGARVGLEQAEALLAEVTELIEGTYLVPSFGRYDDMAALVTRLKRSRTIASSN
>A0A841LLS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. AK013|TrEMBL
MKITDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QANGLLQKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHSYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMSTDFKYLKKKVEAGAEFIVTQMFFDNQKYFDFVKKCRENDINIPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNNEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKKIAKAIF
>A0A536P4M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
GQITLAQAQAAFQEQIEGLLEGGADLLILETFTNLPELLAAVRAARAATADLPIVAQMSF
AEDGLTLAAEEPSQVVAALQAEGVDVIGVNCGVGPQVALNVVETMRPLTRRPLSAQPNAG
LPARVEGRFFYFATPDYFADFAREAQQAGVAYIGGCCGTTPAHIAAMRDALKPKAASQAA
ARQQPAAAPIAIDLTPTDQLPRTPFAQKLHDKGFVISVEIDPPRGLNPAKHLAGAQLVKD
AGADAIDIGDSPMARVRMSALTLAIMIQQQVGIDTLIHFTSRDKNLMALQAELIGAHALG
VRNIIALTGDPPNVGDYPSATGVWDVDSIGLIKIITRLNQGFDWLGTSIGKPAAFTIACA
VNPTAEDLDHELDRFRQKIDAGAHLAMSQPLYDRETLERFFERTGPLPIPFLLGVLPLQS
SRHAEFMHNEVPGIVVPQQLRERMRKAGENGIQEGLEQSRELLEQTRGMVQGVYLMPSFG
RYEMVAELVRGLRARRTVG
>A0A7J8ZPV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium laxum|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGIATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFINDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DALVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A1G1CAD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium RIFOXYB12_FULL_65_16|TrEMBL
MLREALRDGSFAVTCEFVPGRGKGGPAVDAAAQFARDLGAAGVTVHAVSITDNPGGNPAI
SPDVLAAEIRQVGGEPLVHFSCRDRNRNAIESRAMALARMGIQNLLVITGDYPSNGCYEG
TSAGVFDLDAVQAVKYLKEMNAGIKVPGKKPGTTASLPATDFLLGVGVSPFKLTEEELML
QFFKLEKKVRAGADFIIPQLGYDMRKFLEIKRYLASRDLNVPVVGNVYVLSYGAAKVMQG
GGVPGCVVTDELVAKLKAESAEPDKGKGKRLERAAQMVAMFKGMGFGGVHIGGFGLKSDD
FVYIIRHGLELEPQWESFIPEVSFSRPNEFYAFPAPVTYRPTRQEKDPVATLSPGCTSVF
FSVWNLLHGLLFDRKALGYRILVAWYRFLEKHKLLGSITHTFEFAVKSVFLGCRDCGDCA
LPDTAYRCPMYRCAKQQRNGPCGGSRDGMCEVYPTEKPCAWIAIYQRLKGAGRIEELRQA
YVPPCRAELRYTSGWANFFLNRDHAAVPAETPAASGAGESAANAGPEPKANIH
>A0A536RJH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSALASLLRSGEFVVTAELNPPKSAAAAVVRRRAEALKGVVDAVNVTDSNRANVAMAAIP
AAAIVRSVGLEPIVQMTGRDRNRIALQADVLGATAIGIENFVFMSGDDPKQGNHPDAVYV
KDLDGVGLVKMAVGMRDQGQFLSGDEIKQPPKLLVGGTASPFTKPMEADLAKTFEKIAAG
VEFLQTQPVFELGTFSRWLVEVRRGAAHDVPIIAGVLVLRSPDQAERLAKVPGLAIGPGV
IERMKKAADAEAEGIAIAVEMVKALKALPGVRGVHLYSIEWPEAVGRVVESAGLLPRPDA
RVPA
>A0A1M7SL14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio litoralis DSM 11393|TrEMBL
MKIIDKITAQQGKPFYSLEFFPPKEKDNWGGFIQTVKELEKINPLFASVTYGAGGGTQEN
TLEITAKVKNECKMETMAHLTCVGADKKKISDFLSRLKQVGVTNILALRGDVPSGQTVDW
DKADFKHASDMVAFVKKEFPDFGISVAAYPAPHPEALSFKKDRLDTALKMRVGSDFAVTQ
LFFDVREYFSLVDDLKALGINMPIIPGVLPIQSLDSIRRILSLSGSNIPGKLYLSLEEAQ
NKGGVEAVKEAGLKFAIQQIRSLLDGGAPGIHLYTLNRSSMCLNIAEEVGALS
>I8A5G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus oryzae (strain 3.042)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNRDFTFAVDLVRYIRQKHGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYL
VEKTQAGADFIMTQLTYDIEAYTRFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVQIPPQILSKLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLRGFHFYTLNLEKT
VSFILERCDLIPPYSEDFDAIEEGGDISAMDGAHLRSLTRRRASSINSLPHNRVIVDKLH
ASEVSSKASVSHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSS
GLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFF
CPSKDYHSILKPLLQKHGHEKLAWFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWG
VFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNDIKDDVWLVCVVG
QDFGAGTEMGSEEEEDEKKFMWRVLLNAKK
>A0A364V5W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium heidelbergense|TrEMBL
MPDSPRPAPLPYRQVAVSDTLRFNTPGRVPFSVEFMPPRDDEAELRLFTAAEAFHDLGVS
FVSVTYGAGGSTRERTLRVARRLATKPLTTLVHTTLVEHTVPELIHMVRAYASLGLTNLL
ALRGDPPGDPTGQWVQTPGGLRYASELIELVTAMPEGRFFDIGIASFPEGHYRAKDLQQD
TEITLRKLRAGAQYSITQMFFDVDHYLRLRDRLAAADPTEGAKPIIPGLMPITSLRSVRK
QMELAGAQLPADIERELLSAAGGDERANRDRIREVGIGITTRMAERLIAEGAPDLHFMTM
NNVRATQEVLHNLGMAPAWGEEYGHDMVR
>A0A2E5JW03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSRVDTTYNDNNKSFVSIVDVSPPRDTNLKTLDNFQNLNPDFLSIAYNPGKIPRVDSLVY
AHMLKERYGIDVIFSTATRDMNKLALGTRMMSASMLGLENAIVLYGDHFSQKELDFVLPV
HNQKPSELIYDSNQLNYGLDNRGSKLPSLSSICIGATIDLNNDIDRELLLMRKKIQAGAG
FFISQPTFDFITFEKFFSRYQMEFDNDLQVPVFWGIQILVKNGLRLGEIPKNLEKAIESD
EDMLPYAINQVQSYLDFGVRGLYVVPPIYRGGRRDYDSAARLLDTIN
>A0A535VSX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLVGGRPTVSFEFMAPRDESEVDALEKTIAALAGHAPDWVSVTYRKATGDKTLEL
VTRIKRQYHIEAMAHLTCANTADETRRILNWMEREGVANVLALRGDPPGPGAPFQPTDPQ
LMHGSDLVSLIRGSGYRFGIGAACSAEKHPESPDLDHELRYMQLKVESGADFLITQLFFD
NRFYFDLVRRAAEAGVELPIVPGLMPVPSRRSLAFMTSMAGATVPAGLESEIAAAADDEA
VRAAGVRHCIAQCVELLEAGVPGLHFYTFNRARAPMEILAALRGQQLLTA
>A0A2E6WJ02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKKFSIEILPKQKSKIAELNPEFFEDVYITHIPGSSLEDLIDTSSEVINNGFNPVPHIPA
RSISDESSLNKTLLNLMNIGVKDLLAIGGSVKNKIGIFDSTLDMFKTGILNNIDFRNIRI
AGHPEGNPDDKNSKESLRDKLIWLKENDYTASIVTQFCLSPELTNIWIKETKNIIKEFGR
EDTKIIIGVAGPSKITTLIKYAKVCGVSSSANFLMKQGLDVTKLIKHSPSSLIEKINGYD
GLHFFPFGGIKELDDWISKYN
>A0A2E5SXF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MCDVSPPXLGMSDSISGLLELNPDMFSVSYNPGKSTIMNSVIAATWLQNQTGIETMFTLA
TRDMNKLALQSLMLGAQFNSLNNVVIVQGDKFSEEEALLACEINDFTPTEMIKATTNMNS
RKDFRGRYIHEPTDFLIGAVFDLNKPWEREXXLVGQKIKAGADFLIAQPFYDIENAXKFM
DYXXEVHDQPLDLPIFWGLQMLEKGSGSFCEVPTKISKNIDRGISTVELATQFIEKFQQL
GIGSFYLLPPFFKGGRRSYLAAQTLLEEFRN
>A0A535JIW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAALASLLRSDEFVVTAELNPPKSAAAGVVRRRAEALRGVVDAVNVTDSNRSMVAMAAIP
AATIVQTAGLEPIVQMTGRDRNRIALQADVLGAAAIGIENFVFMSGDDPKQGNHPDAVNV
QDLDGVGLVKMAVGMRDQARFLSGDEIKQPPKMLIGATASPFTKPVEADLTKTFEKIAAG
AEFLQTQPVFDLATFSRWLIEVRRGGSREVPILAGVLILRSAKQAERLAKVSGLAIGPEV
IARVKNATDAEAEGIAIAVEMVKALRSLPGVRGVHLYAIEWPEAVGRVVEAAGLLPRPEA
KVPA
>R5VH43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides plebeius CAG:211|TrEMBL
MKVIDLIKNSKEPVFSFEILPPLKGNSIQKVYHIIDKLREFDPKYINITSHHSEIVYLPQ
PDGNLKKTTVRKRPGTVAIAAAIQNKYGIQAVPHIICKGFTKEETEYALLDLNFLGINNL
LLLRGDSKPLDIAEKDLCLYHEHATDLQEQVNRFNQGIGLDGSKIEGIETPFSYGMACYP
EKHEEAPNMESDLFYLKEKVRNGADYVVTQMFFDNEKYYAFVERCRQEGIDVPIIPGIKP
VVFKNQLNVLPKVFRTDIPEAFASELRKCTTDEEVKAVGVEWCKAQCKDLLAHGAPGLHF
YTFMASDSVYKVAKEVY
>A0A3D4WM29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonosporaceae bacterium|TrEMBL
MPGPRPRISDLLRAGEPTFSFEFFPPKTPEGERQLWQAIRELEPLRPDFVSITYGAGGST
RDTTVSVTERIATETTLLPMAHLTAVNHSVAELRHVIGRYSDAGIRNMLLVRGDPPGDPQ
AEWIRHPQGVSHADELVSLVKASGDYCVAVAAFPEKHPRSPDFDSEVHYFVRKCRAGADF
AITQFFFNWEDWARLRDATAAQGCEVPIIPGVMPVTNVSQIERMAQLSGAQFPEKLAERL
RAVADDPIAVRAIGVEVATEFGAKLLSEGAPGLHFITLNRSTATREVWQQLRVGAIA
>A0A2E0MDZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKKFSIEILPKQKSKILELNSDFFEDVYITHIPGSSLNDLIDTAKEVSVYGLNPVPHIPA
RSITNENLLNETLXSLKEVGVKDILAIGGSVKEKVGKFDSTLDMFSTGALNNIGFKSVRI
AGHPEGNPDDKNSIQSLKNKLIWLKENKFSASIVTQFCLSPEITNDWIMETKKLIKDFGE
DGTKIIIGVAGPSKITTLIKYAKVCGVSSSANFLMKQGLDVTKLIKHSPTDLIEKLDGFD
SLHFFPFGGIKELDDWLSKQK
>A0A5J6ENA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces galilaeus|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFYAPKTSQGERSLWNALRRVEAVAPDFVSV
TYGAGGTTRATTVKETQQIVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVELIKESGDFCVGVAAFPEMHPRSSDWDTDVARFVD
KCRAGADYAITQMFFDPESYLRLRDRVSAAGCATPVIPEVLPVTSVKMLERLPQLSNAHF
PAALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>H2IXH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rahnella aquatilis (strain ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 / NCIMB 13365 / CIP 78.65)|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRQIARDYWESGIRHIVALRGD
LPAGGGKPEMYATDLVHLLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPHWMNSLFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPDIAVPV
RA
>A0A2E1BH74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSMHSLEIVPKQLDRLKFLPINKFEDVFVAFIPGDNYLNIINACKSLLESGYNPIPHIPA
RTXASKEQLEDFLFQLSSLGVKDILVIGGSPKKQEGPFSESMDLFQTGLFSKYVFTINIA
GHPEGNPDDSESDLNLIEKSKWLFENKLNFSIVTQWTLDVEKTNRWIHEIKNKLIQDIDQ
DIKIKIGIAGPAKLTTLINYAKICGVSATALIVRNKKFGLTKLVKHNPTEIINGLKNYDQ
LHFFPFGGIKELSGWMEK
>A0A3L7WY02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSRLQRVLRSGRFAVTAELNAPDSADPEDVYRNALVLSEVCDAINATDGSGANCHMSSMG
CCALLTRAGYEPVLQVSCRDRNRIAIQGDLLGAAAMGVQNVLCLTGDDVSAGDQPEAKRV
FDFDSLQLLRTAKIMRDEGVFLSGRKLTTPPRFFLGAAANPFVPPQEFRHLRLAKKVEAG
ADFIQTQYCYDVPVFQEYMRRVRELGLHERVYILVGVGPLRSEKAAEFMRTKVPGVWIPD
AVVDRLAKTPPKRKRDEGMQICVEIIEEVRHIAGVHGVHLMAYRQEETVAEIVERAKLFP
RDPLPEPRNRREKKPDPANQQNAL
>A0A290MGZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter vibrioides|TrEMBL
MTLPPTRRVIGPVARAGERTGRPRVSFEFFPPKTPQMEESLWAAITRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRDEVDEVIREYWETGVRHIVSLRGD
PPPGEGGIGGVYVPRADGYANATELTKAVRAIAPFEVLVGVYPEKHPESPSLEHDIDVLK
QKVDAGATLGISQFFFDLDAFLRFVDKVRAAGITIPIVPGIMPVTNFVGLKKMAAACQTA
IPSWLGNLFDGLEHDAETRRLIACSVAAEMCAKLQEQGFEDFHFYTLNRADLVYAICRVL
GVREVSPAASEVAA
>A0A223D683|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tumebacillus algifaecis|TrEMBL
MATWLYQQGHAVGSSTEELCLKNQEWVREAHLAYLHAGAQVIETNSYAANREALARYGLE
RKTTRINRAAVQLARQAVEMAEADAFVVGSIGSIAAARVMTSNVEEFRDIFEEQAVALLH
EGVDGLILETFFDLEELLLALDVVRPLVATSGVPIIAQCSLLDVERTRDGYLLSDAFYQL
KEAGADMVGLNCRLGPAEVLRAMEKAVVPAGLSLSAFPNAGRPAIIDGEFAYKPNYQYFG
DNAIKLWEQGVSLIGGCCGTTPEHIQAIAGAVAGLKRLPRINPEHTPRIEVFEREVVRFQ
QSEQPTIVELAEKRHTVIVEFDSPRDLNVERYVEGAHELYKAGADAITIADNSLATTRMS
NMALGSIIKRELGIEPVVHVACRDRNLIGQQSHLMGLHALGINQILVITGDPARVGDLPG
ASTVFDMSSFDLIRMVKQLNQGIAFSGRPMNNQARFVCGAAFNPHVRNLEAAVARLERKV
DAGADYIMTQPVYDVETMLAIREATAHLKVPIFIGIMPLTSTRNAEFLHNEVPGIKISQQ
SRERIKKFEGAAARAEGVEMCKELLDEAVKSYNGIYLITPFSYFEMTVELTKHVREITQV
SSRASNF
>A0A385T992|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus laterosporus|TrEMBL
MGKRDLRAYLTEHLLVGDGAMATQLYEQGVPIGVSYEELCLSNPQIIRNVHAAYYEAGAR
LIETNTFGANRDSLSRYGLENKVTRMNRAAVTIAREAVGDDAFVVGAMGSIIAGRVRDKQ
IDQFKDQFEEQATSLLHAGVDGILLETFLDVDELLLALEVIRPLTELPIIAQLATLEVGT
TRDGHSLTQAFQLIKGAGADVIGLNCRLGPAEILRSFEATVCPSDVYLSAFPNAGRLGLA
DGTLSYKSSPDYFAESALRLHEQGVRLIGGCCGTTPEHTRAIAEKLAGCAPVPRVNPPVS
VHSETIEVQAVQKRLEPSIIEEVKHHPTIIVEFDPPKDLHTEDFLQGCCALHAAGANAIT
LADNSLATVRMSNMALGAMMKRLGVEPLLHIACRDRNLIGQQSHLMGLHALGIDQVLVIT
GDPSRFGDLPGASSVYDVSSFDLIRMVKQLNQGYAFSGKQLKQHAQFIVGAAFNPHVRHL
DAAVARLEKKVEAGADYIMTQPVYDAETIVQIYEATKHIRVPIFIGIMPLTSSRNAEFLH
NEVPGIKLSTYALEQMKLFTGEAARQEGNRMAKELIDVTLQYFNGIYLITPFNYYQMTVE
LTQYIRQQEQVKAGFKEVSSS
>A0A7V1I3M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfofervidus auxilii|TrEMBL
LAPIVQITIRDKNRLAIQSDILGAVTLGVKAFFCLEDCHQRVGDNPGAKGVFDLDCVQLI
SIMKKIEHSLVGTRINPFAHPLELHLVNLSKKINAGVDFIQTMPVFDLERFKEFISLIKG
ENLYLLAGVRPIKSWQALQSMSQMVIPENIVQRIKNTPENKQAEEGIKICVEIIKALKQI
KGVNGIHIFAHDWEEAVPILVRQANLK
>A0A840J7H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGAAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCQRLIAGGAPALHFYTLNLAKPTTQVLQLLGC
>A0A840VUD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora parathelypteridis|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTEVGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATDTTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWIRHPEGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVATDTAQFVR
KCRAGAEFAITQMFFEADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARL
>A0A8B5XCH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerobacteraceae bacterium|TrEMBL
MAHPFVTRLSQGVMLCDGAMGTAIHDRGVPFDVCFDELNLTQPQMIVEIHREYIAAGAEI
IETNTFGGNRFRLSEHNLTDRVREINLRGAKLAREAREVSGQPVFVAGSIGPTGRTVEPI
GTARQGPVRDAFREQVEALLEGGVDLLMIETISSLDEMRLAVEAARAGSDLPIVAQMTFA
DDGRTIGGNTVADVVEMLSSFNVDVIGVNCSVGPRHTVDVLKELTVVGGPEIHYSGQPNA
GFPAQVGDRVMYPSSAEYFAGYAREAVGLGLSIVGGCCGTTPQHIRAMRTAIDQVEQEDA
SQSSTPAITVRDSSRAAAVYAYEGPTLLAQKLGKEFVISVEVDPPKGLNPTKTLAGARLL
KDAGVEFINVADSPMARVRMSALTLCYLIQHEVGVETILHFTTRDRNLMGLQSDLIGAHA
VGVRNIIALTGDPPSLGDYPDATPVYDVDSVGLVRVIKKFNAGTDSAGSSIGQEASFTVA
VAADPTRPDLEEEADRLSRKIGNGGDLVMTQPVFDFQTWIDFLQIYERKYGPIPVPVLLG
VLPLQSTRHAEFLHNEVPGIRLTDTARERMRLAGNKGRVEGVKLAQELILQARESVHGIY
IMPSFGRYEVAAETASIITDRQLASSLSNNS
>A0A2E3D3U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium|TrEMBL
MNSQRQHEKRFSFEFFPPKTDVGVEKLNLVQQELAEKKPSFFSVTYGAGGSTRDRTFDTV
MNVKAKTGIDAAPHLSCVGDTKAQLAELLNQYKDNGINRIVTLRGDLPSGMGASLGELKY
ASDLVAFIREQTGDHFHLEVAAYPEMHPQAKSMDADLQAFKTKVEAGANSAITQYFFNVD
AYKFFVDSCEKMGLDLPIYPGIMPIINYDNLVRFSGMCGAEIPRWVRMRMEGFRGDEQSI
KQLGEEIVTSLCEELLDMGAPGIHFYTMNQAAPTLAIWNNLNL
>A0A3N0VS80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium daecheongense|TrEMBL
MKITEHIKKADGKTLFSLEVVPPQKGIGIEDLYRNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVHQINNLGRGKYLHDEDQVCDEHNKFCIGVAG
YPEKHIEAPSMNYDLKWLKEKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGI
KPIATKKHLKLLPQVFKIDLPEELINEVEKAKNNEAVKEIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>L0MPG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. FGI94|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSSLKPKFLSVTY
GANSGERDRTHGVIKGIKDRTGLEAAPHLTCIDASREQLSEIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPSWMTSMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A0N0SLH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WM4235|TrEMBL
MALGTASTWSDRAHTVRELIASGRSYSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSVT
YGAGGSTRGGTVRATEAIAANTTLTPVAHLTAVDQSVAELRHVIGQFADAGIRNMLALRG
DPPGDPMADWVKHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSDDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVAKAGCDTPIIPEVMPVVGIKQLDRLPQLSTAVFP
SAVKDRMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A0D5A740|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. B7740|TrEMBL
MTRTPSIVDRLRTEPEARIPFSVEFSPPRDAAAEARLWRAVREFEQLQPAFVSMTYGAGG
STRDRTVRVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRGITNILVLRGDPPGD
PLGDWEKHPDGVEYAEELVRLVRDLGDFHVGVASFPEGHHRAGDLEQDTRCLVGKLRAGA
EYSITQMFFDVDDYLRLRDRVSAFDAEQGAKPIIPEIMPITSLRSVRRMLELSGTTLPSH
LDEKFTRAAGSGPEEDRAAVREVGIELATNIGERLISEGAPGLHFITLNFARATREVLSN
LGLAAARV
>A0A7K3EQX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5606|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPAADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVRHFVD
KCRAGADYAITQMFFQADSYLRLRDRVDTAGCETPVIPEVMPVTSVKMLERLPKLSNAAF
PPELKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A8J3W7L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planobispora longispora|TrEMBL
MTTRPFDIICEVEPPTRPDLKHVRHQIGTLSRIADSFLIPDNHIGRATVSSVAVAHEVQA
MGGRSIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVYGDKPTTGNRTSDLTVRSMIEEV
RSLDGDPAFAGIPAFQVGAAAGLRPLPAWKRAADFMFVQVSFSLDALLRWREANPVDVPV
YAGVMVVASENHARRMAAAIPDIDIPADLVERVADDRLAGVEAACEQVLRIRDSGAFDGV
HLVPVARYREVESRLSGIL
>R7PKU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium clostridioforme CAG:511|TrEMBL
MDDAEGRERLKMKIREILAEGKPTLSFEVFPPKTEDAYDSVEKAAAKIAKLKPSFMSVTY
GAGGGTSDYTVGIASAIKEEYAVTPLAHLTCVSSTREKVHHVLGELKERGIENVLALRGD
IPQDGSTPKEYHYASELIREIKKAGDFCIGAACYPEGHVESANKSVDMDYLKQKVEAGCD
FVTTQMFFDNSILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTCLPSRFMSI
VDRFGDNPAAMKQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A6N8GKN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria sediminis|TrEMBL
MELSQPPGSTPGRPAPSLGVTPGGSVRRPPDRTAPPPSLSYELYPPRCAASAETLLRTIE
ELEPTRPDHVAVTYSGDAPRRAGSLALLDHLLARTGLRPLAHLTCVGSTRAELEETVTSL
LHRGVRGVLALRGDLEPDAEPGELAHAGDLVELVREVEQRHTASLAGGRLAVGVAAYPTR
HPESPSFRHDIEVLLAKQRAGADFAITQVYFRPQRYERLVASARAAGVTIPIVPGIMPVT
EPRRLATLCRLAGLRPHPGLAAALEEAAGPAERHRAGVAFATRLARAALDAGAPGLHLYT
FNEHRAALDLLERVDLPRVPHQPAALPDLLPA
>A0A6S7FAV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter insolitus|TrEMBL
MSDSISPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCEAAPHLSCVGASRQDLRDILQAYKNDGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQALNPSADLDHFVNKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVNVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPMAVWKELSLQA
>A0A285CIH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cereibacter ovatus|TrEMBL
MARPRISFEFFPPQTLEASFRLWETAQMLAPLKPDFVSVTYGAGGTTRKLTHDAVATIHT
HYKLNVAAHLTCVDATKAETLEIANSYAEVGVTEIVALRGDAPKGAERFTPHPEGFASSI
ELVEALAATGKFKLRVGAYPEPHPDSADTLADVRWLKRKIEAGATSAITQFFFEAETFLR
FRDLCVKEGITAPIIPGILPIDNWNGVKKFAARCGSQVPGWLDEAFAHAKRDDREELFSV
ALCTELCDKLLGEGVEDLHFYTLNRPTLTREVCHALGILPDVALQNVA
>A0A1T3JNK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia anophelis|TrEMBL
MKVTDHIKEAKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGEKYFEPTKGGNRYASDLVTQINDLGKGKFLHGEISGNDTNNSFCIGVAG
YPEKHLEAPSMQYDLKMLKQKVELGADYVVTQMFLDNQKYFEFVKLAREAGIDVPIIPGI
KPLAVKKHLQLLPQVFKIDIPEDLVNAVSQCKNNEAVKQVGIEWCVQQCKELLDFGVPAL
HFYTMGKSDNIQKIVSEFF
>A0A1Y3DDL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4973|TrEMBL
MSKRIPVSFEFFPTKTDVGAEKLRVVHQELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYASDLVA
FIREHSGDHFHIEVAAYPEMHPQAESFDQDIQNFITKARAGANSALTQFFFNPDAYFYFV
DRLQKEGVDLPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNQTEPNRQLVLDLGLA
>A0A454VXY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC02707|TrEMBL
CRAGADYAITQMFFDPENYLRLRDSVVRAGCETPIIPEVMPVVNVKTLDRLPQLSNAAFP
ARVKERILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLGL
HQQS
>A0A0C1YIE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio owensii CAIM 1854 = LMG 25443|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDASRDELINIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>F2LHI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia gladioli (strain BSR3)|TrEMBL
MKPIELSLEFFPPKTAEGADKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLSAAPHLSCIGSSKDNLRAILDQYRSHGIRQIVALRGDLPSGMGEVGELRYACDLVRF
IRAEHGDWFHLEVAAYPEYHPQSRSPKQDLQHFADKVKAGANSAITQYFFNADAYFRFVD
DAARLGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGADV
ITAMCDRLIKQGVPGLHFYTLNLATPTRVVCERLGLSG
>A0A1F2XR79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium RBG_16_64_48|TrEMBL
MLASPERKSRFLGGGDIDVSFEFFPPKTAAMEETLWRSIRRLEPLDPRYVSVTYGAGGST
RERTHATVARILRETKLKPAAHLTCVAATRAEVDEVIRDYWDLGVRHIVALRGDPPGGVG
ERYQPTQGGYVNAADLCAGIKRIAPFEISVACYPEKHPESPSVEADIDMLKAKIDAGAST
AITQFFFDNEVFFRYLDRVRAAGITIPIVPGLIPIHNFKQISGFAAKSGASVPDWLGHRF
EGLDEDQETRHLVAGAVAAEQVLGLVDQGITEFHFYTLNRADLVYAICYLLGLRPVATTK
AEATS
>A0A5C7VSW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas oligotropha|TrEMBL
MESQKKFPPTFSFELFPPQTPEGVEKLRLTRQQLARFNPKFFSVTFGAGGSTRERTLETV
LEIQTEGHVVAPHLSCIGSTQQNIRAILEKYYEAGIRHIVALRGDLPSGMAQAGEFRYAS
ELVAFIRQEYGSSFHIEVAAYPEYHPQARSAQADFDNFKRKIEMGASSAITQYFYNADAY
FHFVELCEAAGLNIPVVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLEGYGDDSESIQA
FGLDVVTGLCEQLLQAGAPGLHFYTLNSANLTSAIWQRLNLHAR
>A0A2A3AZF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM4313|TrEMBL
MTIRQIDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFRTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHLLHDEITETQVDMVK
TAH
>A0A7Y0GYF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciimonas sp|TrEMBL
MSKENFSVEFFPPKTAEGTEKLRATRAKLTVLHPKYFSVTFGAGGSTQQGTLDTVLEIMG
EGLDAAPHLSCVGSSRESIRAILADYKAHGIRRLVALRGDLPSGYGGAGELRYASELVEF
IRSETGDWFHIEVAAYPEMHPQAKSPQDDLRNFARKVQAGANAAITQYFYNADAYFEFLD
NAHKQGVRVPVVPGIMPITNYSQLMRFSDMCGSEIPRWIRLKLASFGDDSDSIKAFGLDV
VTQLCERLLAGGAPGLHFYSMNQSAPTSAILQRLK
>A0A4U0VEC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Friedmanniomyces endolithicus|TrEMBL
MHITKKLAQAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGFGPAFIDVTWGAGGRMS
HLTCEMVKVAQSAYGLETCMHLTCTDMAQSKIDGALDEAYKAGCTNILALRGDPPREKEK
WEQSEGTAFRYAKDLIKYIKEKYGNHFDIGVAGYPEGCDAETDADAHIPYLKEKIDAGGT
FVLAQMSYDVDIFIDWVKKCRQAGIPENVPIIPGVMPIQTYDSFLRRAKWTQCRVPKHWL
EQLEPIKNDDAQVREVGKDLVAEFCRKLLDSGTTMHLHFYTMNLAASTRMVLDELSVAPA
ADSHNPDLKPLPWRQSLGFNRRDENVRPIFWRNRKQSYVARTQDWDEFPNGRWGDSRSPA
FGSLDAYGIGLKGTNEHNRKLWGEPKTAQQVAELFVGYMSGKVESLPWSEAPISSEADSL
RQDLIDLNSRGLLTINSQPAVDGAKSSHTTYGWGPKNGYVYQKAYLEVLIHPAILPKLIE
RMEEKEEITYYAVNHSGELKTNVSSDGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEF
YHLGLEWSKCYDEATESRRLIREIAESWYLVNIVDNDYRDSRGIFPLFDGLRVDGVDVKT
KPITNGDANGFVARTRDGTSIADTETGQNIAKNADHASEKLSEAANTAGAKVKEAANTAS
DKTKEVADSASAKAKETASSANAKANDAAGSAKAKANDTADSTKAKANDATSGTTTSTSG
STTEHSATSVDKVTEETETVADQTVAPAVEHDTIKREHETRDRDVVEKEIHKDHYHTTIQ
PLKDTEVQATEHEFEQAPTEYRSVEKDDGAAEAKVAKKLAGFHDSVKEEETKETHAQDET
VVGEHVHHHLHEIIQPVIEKGKEVIQRSVTHVTHPIKETVHEKSDDHGVTKAKPISVEEF
KHRLDGEAATEVNPDKPAP
>A0A6J6T4F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MGGRRGSGGAAPRTLDIMSIGRGRSLREVVEAGEKSFSFEFFPPKDEAGEAQLWDAVRAL
EPYRPTFVSVTYGAGGSSRGTTVRVTRRIAQETSMLPMAHLTCVGHTRTELEAVLDEYAA
AGVHHVMALRGDPEGGPRADWTPTEGGLTYATELVELVAARGEFRIGVAAFPERHPSSPS
LDHDADVLAAKARAGAEFAVTQMFFRAEDYVSLVERVRARGVDLPILPGIMPILNLAAIR
RQGELIGTDVPEEVVSRIAAHEGDAVSMRAEGIALAAELCQDLLDAGAPGLHFYTLNRSK
ATLEIFEKLDVRP
>A0A7Y5GMT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriaceae bacterium|TrEMBL
MKVTEHLQKAAGPLISFEIIPPKRGGDIKGLLAVIEDISKYNPPFIDITSHAAEVYYDET
DTGIKKIIKRKRPGTLGICALIQNKYNIEAVPHILCKGFTREETEDFLIELNYLGIENVL
AIRGDDSGYNKPLPAGRSANVYAGDLVQQIADMNKGKYLEEGLLDAKPSNFCVGISGYPE
KHFEAPNLETDILYAKKKVEAGAEYIVTQMFYDNKVFFDYVDKCRAAGINVPIIPGLKIL
AVKSHLTTLPRDFYINIPVELSEEVMKAKPDHVLDIGVDWAVRQVTGLLDRGVPAVHFYI
MQNSRPVTKLMDKLKLHKKIF
>A0A6J7A2T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTIPSVSFEFFPPKDSEGESRLWEAMMNLRSIAPDFVSVTYGAGGSTRDRTIEITTHITE
RTSIPTVAHLTCVGSTQEEIGEILMRYRDAGIKSILALRGDPPGGPSTPWTHTPGGLDHA
DELVALAAEFGDFTIGVAAFPDGHPASHGNFDQDVNVLLRKEELGASFATTQFFFDVNKW
ISLVNRLKERGSQLPIIPGILPISSVKQLVRMAELGGTPIPDDIHAKFLSIESDDAAVKA
LGIEIATKLCIELLDAGAPGLHFYTMNSSAATREIWENLGLKR
>A0A1J4NET2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. LCT-H3|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLAPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKSIQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHKVAGIVITPHMLRVLAQEEQDGRTENA
YKRCAIQILMCKYLSFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVKT
KNELVPELAYYSRQLSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASFWENAPAAKA
LLKTEFISKQGIVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A6J7AYL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVVRTSYSLEFFPPKDGEGEARLWDALESLKRINPTFVSVTYGAGGSTRNRTIGVTEEVT
HRTNFPTVAHLTCVGSSRQELISILHMYKAAGIKGILALRGDPVGGPRAPWTPTSDGFTH
ADELVQLIHEFGEFDIGVAAFPDGHPGSDGDSKKDIDVLLRKEFLGAQFATTQFFFEVSK
YEQLVDGLQARGSSLPIIPGILPITNVKQLQRMAELGGTPIPSDVAKSFGAVENDPIAVH
QLGIELASQLCEDLLTAGAPSLHFYTMNNATATLEIYGNLNSAN
>A0A6I7YFJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. me109|TrEMBL
MALGSASTRTDRARIVSDMLASGKKTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVAHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDSDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCGTPVIPEVMPVTSVKMLERLPQLSNASF
PDVLKERILTAKDDPAAVRSIGIEFATEFCAKLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPQQT
>A0A0E3R9N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina mazei SarPi|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRFSASLEDASQLKGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDYPTCGDHPGSKP
VYDVDSVQLIELVRKLDTGVDFAGNKLDGGTSFCAGAVSGIDPEKTMQLIKLQKKVKCGA
DFIQTQAVYDIGMFEEFMDAVNYLEVPVIAGLIPLKSLGMAEFMNKNISGIHVPEEIMLR
MKDASSPMEEGLLIASETIKELTKLSRGIHVMPIGSHRNTARLLSLAGISQK
>A0A6J5YS76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSQLESIAPDFISVTYGAGGSTRDRTIRITSEITARTHIPTVAHLTCVGSTREELIDILG
KYRDAGIKSILALRGDPTGGPRARWSPTAGGFNHADELVTLAAEFGGFTIGVAAFPDGHP
ASNGDFDKDVDVLIEKERRGATFATTQFFFEFDKWKKLVDKLEAKGSALPIIPGILPVTN
VKQLNRMAELSGTPIPAHISDSFSKVEGNTEDVRKLGVEIATKLCQELLDAGAPGLHFYT
MNTSSATREIYSHIKDER
>A0A544T0K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacillus soli|TrEMBL
MGLLDKLRTNMLTADGAMGTLLYSYGIDYCNEELNIERPEIIEKIHQDYIAAGADIIQTN
TYGANAIKLERYGLENSVKEINEAAIQIAKRAAAPGGQFVLGTIGAIRGIRKSDATIEEI
IQMVDGQAKHLLTGNPDGLLLETYYDFEELAATVTHLRKLTNTPIIAQVSMHDPGILQNG
LSLNDALNQLDALGADVVGVNCRLGPFHTIQALEEVALPKNAFLSAFPNASLLDMEDGRL
VYESEADYFGKAALLLREEGVRLIGGCCGTTPKHIEAAKKLIGHLPPLTAKVVTPKKPII
IREAEPNSHEPLHEKAQKERTIIVELDTPRHLDTTTFMEGATKLYDAGVDAVTMADNSLA
SPRISNMAMGSMLKLQNNIRPLAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSLELIQLIKQLNEGISFSGKSLRKKANFSIAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVYTKEKIQEIYEATKHLTTPIFIGVMPLTNIRNSEFLHNEVPGI
KLSEEVLARMRACGEDRARATAEGIQIAKELIDTAAELFNGIYIITPFFRYDMSLELIDH
IKEIDGKKVRENSYV
>A0A1Z8Q8J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium TMED29|TrEMBL
MTGISFEFXPPKSPEAEEKLWRSVGRLEPLAPDFVSVTYGAGGSTRDRTHTCVRRLVDET
GLQPAAHLTCVAASRAEVDSVVEAYAEAGVRHIVALRGDMPDMGGXAPHTDGYDGSVALV
EAISARGGFDXTVSAXPEKHPESRSLDDDIDLLKAKXDAGATRAITQFVFDTPAHMRXRD
AVAAAGVSIPIIPGIMPTTNFAGARRMAAACGTCVPDWLSAAYEGLEDDLDTRKHIAASI
ATDQCRTLIDEGFEYLHFYTLNQADLTFAVCRILGLGGDQQESDVV
>A0A5J6GMA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces kanamyceticus|TrEMBL
MALGTASTRTDRARTVRDMLATGKTMFSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGDWIAHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSPDWESDTRHFID
KCRAGADYAITQMFFDPEEYLRLRDRVEAAGCRTPIIPEMMPVTNVRQLERLPQLSNAVF
PAELKERILSVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHQA
>A0A5C6RLI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeodactylibacter luteus|TrEMBL
MKVTDYFEKANGQTLISFEVLPPLKGGSMQAIFDTLDPLMEFKPPFIDVTYHREEFIYKM
RPSGYYEKTAIRKRPGTVGICAAIMHRYGVDAVPHLICGGFTQEDTENALIDLNFLNINN
VLALRGDARKFDGRFVPEENGHAYAIDLVRQIEHMNQGKYLDANIDKGASTDFCIGIAGY
PEKHFESPNIDMDLAFTKAKIDAGADYIVTQMFFDNQKYFDYVERCRAIGINVPIVPGLK
PITKLYQLNALPRIFHIDLPDALVKSIQDAKGTEGRRQAGIEWCIQQSKELKAAGAPCLH
YYTMGDADTIRQIAEAVY
>A0A1N6VHJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. RU4X|TrEMBL
MSTPTLKDKLLSRQSGIITYGMTPPKNTHPAEKVREIADKQIERLQGIGIDGLVLYDVQD
EAQRTDKDRPFPYLASLDPTAYYRDYLQQELGLPAVIYRCVAGGSRSELEEWIHQNRDEQ
RYSVFVGASSSRQQVQVKLPEAYRLGTSLNEKLMLGGVVIPERHRGKGDEHLRALHKQES
GCAFFISQATYDVEASKSFLSDYYYHCRDNGIGMAPILFNLAPCGSAKTLEFMKWLGISI
PKWLENELVHSHDILDKSVQLSRETFRELYQFGLEKGMPIGCSIESVSTRKVEIEASIQL
VKDIKSDMSR
>L7F1F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces turgidiscabies Car8|TrEMBL
MGTSGLRGLRSLLERVRYEVLPAKTTEEKVLAHLPRDAVVTVTASPVKGLEPTLDLAGRL
ASHGYRVVPHVPARLLRDDAHLKDVVDRLRELGVEDVFVPAGDANPPAGSYEGALPVLRR
LSELGSPFTHVGVTGYPESHPLIHDDVTVQAMWDKREHATYIVSNLCFDARVLGEWVGRV
RRREVALPVYVGVAGPVQRAKLLSMATKIGVGESTRFLTRHPLWFLRFAAPGGYSPERLL
SRAEGALTAPGAGVAGLHLFTFNQVEETERWRRGVLERLGG
>A0A0R2CGJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus vini DSM 20605|TrEMBL
MQQNPPSLSFEVFPPKNLIANHPAFQQLLQQLADFNPAFISVANSNHWLNFKTSTLAIAD
TIQTDFQLPAMIHLTARYLSQAQVLQLLPELKANKVKNILVVRGDATPGLADQGDFNHAS
DLIKFIKKHDHSFQIFAACYPEKHPEAQSLATDIAHLRQKVAAGCDFLISQTFFSNELFY
NFQTACSQAGIKIPILAGIMLLDNRQQIIRFLQKSNLTLPPKLQAILATFRVNSAGFKQA
GVQFTIDQINDLLDHQVAGIHLYTLNHSKITRRVCQAIHARFLKSK
>A3P0L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei (strain 1106a)|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A7W9LMR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiangella mangrovi|TrEMBL
MALGLPSTMPGGARTIRELLASGGRSFSFEFFPPKDERAEAAFWQTMRELERLQPTFVSV
TYGAGGTTRDKTVRITESVARDTTLTVVGHLTAVNHSVAELRNIIGQYADAGVRNFLALR
GDPPGDPRGEWVKHPEGYEFSEDLVRLLGATGDFCVGVAAFPDKHPRSPDLETDARFLAR
KFQAGADYAITQMFFHADAYLRLRDRVAAGGGEAPIIPGIMPVTNVRQIQRFAVLTDADF
PAPLADRLLAVEDDPEAVRAIGVEVATELCERLLAEGVPGLHFITLNKSTATREIYQNLG
VGVPS
>C2FTE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium spiritivorum ATCC 33300|TrEMBL
MKIIDHIQNAKGKTLFSFELLPPAKGQSIQSIYKTMDELMEFKPPFIDVTYHREDYLYKE
HANGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARRGDADFIPTEGGHSFATDLLEQVANMNQGRYLHEDIETSEKTNFCIGVAGY
PEKHFESPNFNTDFKFLKKKIEMGAEFIVTQMFFNVQKYKDFVIKCREHDINVPIIPGLK
PITSKKQLVTLPRVFHLDIPEELSDAIADCHTNADVRQVGQEWLVQQCKELIEFGAPVLH
FYTMSNPGPTKKIVEQLF
>A0A433DMH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jimgerdemannia flammicorona|TrEMBL
MKVIDKINKAIKENQPCWSFEFFPPKTPQGVQNLYDRMERMYGMGPEFIDITWNAGGVTS
DLTAEIVTTAQSVYGLETMMHLTCTNMPKEKIDIALREAKACGCRNILALRGDPPRGQTE
WQACDNGFEHAIDLIKYIKEQYGDWFGIAVAGHPEGHVDNRDLEEDILFLKEKVDAGADL
IITQLFMDTDIFLQFVDRARRVGIMVPILPAMFAIQSYNFLKRVTSFDNNHVPQQIWDDL
EPIKHDDEAVKAYGVDLSVRMVRELYAKGFRAFHFLTFNLAKSTRLTLEKLGWVPSLEMV
KPLPWKPSLSTKRAKETVRPIFWKNRTHSYVQRTENWDEYPNGRWGDARSPAFGEIDGYG
VTLNFTPEECLTMWSRPTTISEICSLFARYCMGELKALPWSAQQLELESDSIRQRLTEVN
LAGYLTINSQPAVNGARSTNPVYGWGPVNGYVYQKAYLEFFVPKEMLTALEEKIAKDGDI
TYFAVNNKGDLKSNSGKEKSPTAVTWGVFPGKEIVQPTIVEEDSFMAWKVWFRCPIRFAV
MDEAFQLWTEWAHLYDSAAGEPDSDARRLIEHVRDTYYLVNIVHNDFQDGEAIWRLFESG
HIKSTSDSPCILFTRTLFLKLSTPHPDERANMKVIDKIHKAEEEGRNFWSFEYFPPKTQQ
FREHSFEKLVRRRCGGATAISVVALKKIGSGPSPGVQNLYDRIERMYRLGPEFVDITWNA
GGVTSQLSVEIVATAQSVYGLETMMHLTCTNMPKEKIDVALKVSRNCGFWKGTGLARGGI
YRSRRQQVLCTVYIEAKDCGCQNILALRGDPPRGASHWEAVENGFSYAIDLVKYIRQQYG
DYFGIAVAGHPEGHVDNRNLDEDIQFLKQKVDAGADLIVTQLFYDIDIFLEYVRKCRAAG
ITVPILPGIFPIQSYNGLKRVISFDNNVIPQKIWDDLEPIKDDDAAVKEYGIKLAIEHIQ
IMMDNGINGFHFYTFNLERSTRLILEGLGFVPAPENVKPLPWNPSLSKKRAKENVRPIFW
KNRIKSYIQRTESWDEFPNGRWGDSRSPAFGELDGYGITLKYTPAECLAMWGTPATSDDI
SLLFAKFCRGEVAALPWSAQQLDPETDAIRQRLAAINLLGYLTINSQPAVNGAKSADKLH
GWGPKNGYVYQKAYLEFFVSPDKLDELIRKIERDPEVTYYAVNKQGDLRTNTKSDGPNAV
TWGVFPGKEIIQPTVVEAVSFMAWKEEAFELWAEWARIYPAADSVSAQLIKGIENSYYLI
NIVHNDFQDDHAIWRMFDLEIDGAISRKLREHSIGAL
>A0A7D5V3C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium brunneum|TrEMBL
MDKITDKIAALPADREYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSKRLVDKALEDAKALGIRNILALRGDPPRKEE
YCDAEDSEDDGQQDFTWAIDLVKYIRRKHGDYFCIGVAAYPEGHSDESHPQDQSLEHDLP
YLVDKVQAGADFIMTQLFFDISAYDHFEKTLREHPSGAFKTIPILPGLMPIQSYQMIKRT
TKLSHAKMPPAIMDRLDAVRGDDEKVKLVGVDIVSELIDQIRKIKNRTPGRRGFHFYTLN
LEKAVSFIVERTGLIPRESENEEALIDDGTLAPPAIQVNGTRASTHSRTSRRHSSVGSDP
YNRVIVAGQPPSHPEWEATGQEAGVPAESINSRANTLAISEGEGVLGREATWDDFPNGRF
GDSRSPAYGEIDGYGVSLHMSVNQAVTLWGSPTSRQDVNNVFVRHIKGEISAIPWSEEGL
SPESSTIQSRLVEMNGKGWLTVASQPAVNGISSSDRTFGWGPVNGFVFQKAFAEFFLPSA
DWHTLAEKLKGSDYFDSVCFYAANAKGDFVSSYISGGRSTRTVAASTNAVTWGVFPGKEI
VTPTIIEEVSFKAWSEEAFGLWGEWAKVYGRGSESGKVLSGIRSDYWLVNIIHHDFIDRE
ALWKLLLE
>A0A7T1Y4D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas campisalis|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGKFAITSEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGAHCHMSSVGVCSLLTRVGYATILQISCRDRNRIAIQGEILGAAAMGAC
NLLCLSGDGVQAGDHPQAKPVFDLDSMSLLEIARGMRDECRFQSGRKIDVPPRIFLGAAE
NPFVPPLEWRPHRLAKKVAAGAQFIQTQYCFDIPRLRDFMLKVNDLGLLEGPDRVFILPG
VGPLASARSARWIRDNVPGVHIPDAVIARLEGAQNQKEEGKRLCMDLLHQIREIPGVSGA
HIMAYRQEHTVAEIIEGTGVLEGRVPWYPGRDNPAELNPESPDALAEEFEPVSG
>A0A1I2E1K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium xueshanense|TrEMBL
MKVTQHIEDAKKKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYID
KGNGLLDKRLTRMRPGTLGICASIKHKYNVDTIPHVLCGGFTKEETEYLLVDCHYLGLDN
VMALRGDAMKDEQYFIPKQGGNDFAVDLVKQINQLNQGKYLHDVMEVDNKSNFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGIMVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIQAIDQCKNNADIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKIF
>A0A2N6JBE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. BH-1|TrEMBL
MSTHNFSIEFFPPKTAEGAQKLRATRARLAQLQPRYFSVTFGAGGSTQQGTRDTVLEIIG
EGHQAAPHLSCIGSSRASLRAILDDYRANGIKRLVALRGDLPSGYGAMDQASSEFRHANE
LVEFVRAETGDWFHIEVAAYPEMHPQARSPQDDVQNFARKVKAGANAAITQYFYNADAYF
RFVDEAARLGATVPVIAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTESIRAF
GQDVVTQLCERLLAGGAPGLHFYSLNQAAPTEAIWQQLVK
>A0A3G4WB92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ADI95-16|TrEMBL
MSGLRELLASGQRSFSFEFFPPKTDAGERVLWNAIRRIEAMAPSFVSVTYGAGGSSRDRT
VEVTKRMVAETTLLPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGNPNATWT
AHPQGLRHADELVSLVRASGDFSVGVAAFPEMHPRSPDWDTDIRHFVAKCRAGADYAITQ
MFFHVEDYLRLRDRVAAAGCDTPIIPEIMPATDARQIGRFAELSGAAFPEELAGRLEAAK
DNPADGHRIGVEYATAMADRLLAEGAPGLHYITLNRSTATLEIHQNIIESRSAHALAHG
>A0A1J4QCW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanisphaera psychrotolerans|TrEMBL
MGFHSARHVEALNQSMAELNGDINVSFEFFPPNSEQMEQTLWSSIERLKTLAPKFVSVTY
GANSGTRDRTHKVIKDIQDKTGLIAAPHLTCIDASRDELRGIARDYWNNGIRQIVALRGD
LPKGIEKPDMYAADLVSLLKEEADFDISVAAYPEVHPEAKSAQADLLSLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTIGIDVEIVPGILPVSNYQTLIKFAGFSNVRIPNWMHQRYQ
GLEDDQNTRNLVGASIAMDQVRVLSREGVKDFHFYTLNRSELTYAICHSLGVRPPVAVAP
>A0A5K1JEE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AK_207A|TrEMBL
MRVDDIFKQAKQAGALPVSFEMFPPKGDLTMEKAREVAGSWAELHPDFISVTYSAGGSGN
KGATADIAHMITDELGIPSVAHLTCISLTREGLKEKIEDFRAHGIRNVLALRGDVPHDAS
NIPDTPDFHYAKDIIPQLVDAGFCVGAAAYTEGHIECDDLQTSIEHLKQKQDAGASFFVT
QLFFDNEYFYRFRERADKAGITVPVTAGIMPFMSKDQVARMVFMCGASLPSPVIKLLARY
ENDPDSLRAAGIEYACRQLENLRDHGAEGLHVYAMNRPSVARACMSAIRGA
>A0A441ZDY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFAEMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFIQVANFSSRCGALVPAWLAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A2D6KCP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MTQGQYSCEFFPIRANEGHQRARESRLALTELNPEFYSVTSGAGGSTREGTLQAIEEIAE
EGVTPAVPHLTGVGETRDSVSALLEHYRSIGVQRLVVLRGDRPSGMIEHGDFRYAIELIE
FIREISGSAFHIDVAAYPEAHPETPSFREDIGFFRDKVKAGADSAITQYFYNVDAYLRFR
DDIADLGITIPVVPGIMPITNYKQLARFSDTCGTEIPRWIRRRLEDYQDDLDSLRAFGAD
VVALLCNQLIEGDAPGLHFYTLNRSGPVLRVVKAMGSLA
>A0A530YTU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNDMRQELIQTRGSAAFAFDAEVSIELAPAQARTFAPQADCFPLGSRVFLTHLPGKPDAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHAAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFSDYREACWPRVNER
>A0A327WIN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PsTaAH-137|TrEMBL
MLATGKTVYSFEFSAPKTAKGERNLWNALRRVEAVAPDFVSVTYGAGGSTRAGTVKETEQ
IVADTTLTPVAHITAVEHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWISHPEGL
TYAAELVELIKESGDFCVGVAAFPAMHPRSADWDSDVRYFVDKCRAGADYAITQMFFYPE
EYLRLRDKVAAAGCDTPIIPECMPVTSVRMLERLPKLSNADFPPALKERILTAKDDPAAV
RSIGIEFATEFCAKLLDEGVPGLHFITLNNSTATLEIYENLGLHDQRA
>A0A1F3ZQC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_67_12|TrEMBL
MSVESGTRPAAADIATHAAELLACGSIEMGAHQPEMAQRIAALLPSGTPVYVNHLPRHSL
ADALASLIAVREAGLEPVPHLAARRIASRSELETFLRRAVGGAGVRKVLLIGGDESTPLG
PYADGAAPIRSGILTGCGVREVGIAGYPEGHPRIPAAALEKSLLEKLALAAAEGLGAFVV
TQFSFAPARVVEYCAGLARRAPGVPLYVGLAGPSSLATLLRFAQRCGVSASLRALRAQGF
GAVQLVTHTDPGEQLATIARYCTVHANCNVVGAHVFSFGGAAETAAWMNRFIASRAAH
>A0A543IZT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermopolyspora flexuosa|TrEMBL
MSPGGTPRQRGSLNPMSLGRSSRLIGRAPTVRELLAAGDRSFSFEFFPPKTPEGERQLWR
AIRELEALRPTFVSVTYGAGGSTRDRTVEIVERITHETTLTPVAHCTAVNHSVRELRHLI
GRFAAAGVRNILALRGDPPGDPTGEWVKHPEGVEYAEELVRLIRLSGDFCVGVAAFPYKH
PRSPSIESDTEYFVRKCRAGADFAITQMFFRAEDYLRLRDRVAAKGCDTPIIPGVMPVTQ
YSTIARSEQLSGAPFPAELAERFAKVAHDPAAVRALGIEHAVEMCRALLDEGAPGIHFIT
FNRSSATREVFQALTPAGVSVGA
>A0A3R7ZAD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces astaci|TrEMBL
MGKIIDRLTELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPREQLREILKNVRAAGIRNILALRGDPPIGSE
RWKAIPGGFQNAVELIRFIREEHGDWFCIAAAGYAEVHTEAWNNPNLPPSDQVRRVDMLR
LKEKQDAGADFIITQFFFDVDKLLQWIRDCRQVGITIPILPGYLPIQTYNSFLKFTNWCK
TSVPPQVEDALVTIKNDDSAVKKYGIQLAVDTCRKLLANNLSLHFYTMNLATTVRTVLEG
LHLIERERGLPWGAPITRSKDGTLEKSIEQTEQDVWNVFVKFIEGSVKQLPWCEQGLSGE
STIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPHLMQ
RLVVRWRSQITPTCRTMHSVPTVWLFVCILLLYVWLLLINGEIGTEYTNSPGPSVTAVTW
GVFPGKEIIQPTVVDTASFAAWKDEAFELWLSQLVLMDFNNVEDSDIFKIFARVITESMT
KDDLRQRVLELEGKNEKLHETVAKLKIIQAEANRELKDLHGDLSTSREENSRLKAQVREL
RSRLAMAEL
>A0A660X4S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRKISFLEYLKDNIVLFDGAMGTMLYSRGIFINQCFDEVNLKKPNLVKQIHLEYVQAGAD
VIETNTFGANRFKLGKFGLVDSLYEINRKGAEIAREIAGSEVWVAGSVGPLGVKIEPIGP
VSIQEAREAFTEQIKALVDGGVDIIILETFYDLHEIEQALLAAKEVASLPVVAQMTIDEE
GKTLFGTGAEYFTKKLDELGADIIGVNCSVGPQPMLDAIEKMVKVTNKPVSVQPNAGIPR
NVDGRNIYLVSPEYMAEYAKRYVMVGAKVIGGCCGTTPEHIKEMRKAIQSLVPRKRHFYV
KVEPEEHKGLEPIPQEKRSSFARKIKEGKFVVTIEMVPPHGTDVSKEIKKAKILKEHGID
AINIPDGPRAMSRMGAVYLAKILMDNVGIEPVLHYTCRDKNLLGIMSDLLGIEAVGIRNL
LIITGDPPKMGDYPDATAVFDVDSIGLVNIVKNLNQGVDIGGNPIGTQTKYFFGVGVNPG
AVSIEYELKRFEWKVKAGAEFAITQPVFDLDTFYNFYRKVEGFKIPIIAGIWPLVSYKNA
EFLNNEIPGISIPDRIMEKMRKARTKEEALQIGIDEAKFILRELRNLVNGVQISMPFGKV
DYPLRVLEAL
>A0A3L6VB61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces astaci|TrEMBL
MGKIIDRLTELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPREQLREILKNVRAAGIRNILALRGDPPIGSE
RWKAIPGGFQNAVELIRFIREEHGDWFCIAAAGYAEVHTEAWNNPNLPPSDQVRRVDMLR
LKEKQDAGADFIITQFFFDVDKLLQWIRDCRQVGITIPILPGYLPIQTYNSFLKFTNWCK
TSVPPQVEDALVTIKNDDSAVKKYGIQLAVDTCRKLLANNLSLHFYTMNLATTVRTVLEG
LHLIERERGLPWGAPITRSKDGTLEKSIEQLPWCEQGLSGESTIIRENLRWINSMGFLTI
NSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPHLMQRLVVRDIFKIFARVITESM
TKDDLRQRVLELEGKNEKLHETVAKLKIIQAEANRELKDLHGDLSTSREENSRLKAQVRE
LRSRLAMAEL
>A0A7C7NAZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
QGKTFYSFEFFPPKTDFGLDNLYSRIDRMASFQPAYIDITWGAGGSTADKTLGMCKTIQK
YFGLEVMMHLTCTNMPVSSIKKVLTEAKENGLSNILALRGDPPDGSSSWKQHENGFRCGA
DLVRYIRKGFGNYFFLGVGGYPDGHHEQSDLDIDISFLKEKVDAGSDIVVTQLFYDVDKF
LFFRDKCIKSNIKVPIIPGIMPIHNYARFLKFTQFCQVSIPDSVSTQLESIKNDDSSVIN
YGIDQAAAMCQKLIENGVPGLHFYTLNLEHSVSAILKSLGFVSSRSTIRELPWRQSASDD
RKTSEDVRPIYWSNRPVSYLTRTENWDDFPNGRWGDIASPSFGELNQYHAIRAGSKSDKV
KARRKKMWGEPKSIKDITDVFVSFCKGKINSLPWCEIPLAIESQQISSDLINFNELGFFT
INSQPKVNGAPSEDVEVGWGGPGGRVYQKAYLEFFTSRDKLDGLLKSMESTDNISYQAIN
VDGDLITNLLENSVMAVTWGIFPGKEVIQPTIVDARSFLIWKDEAFSLWMDDWASIYKAK
SESYEIIKEIYDTYYLVNVVDNDYVAGNMLQQILKS
>A0A7Z0KN53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. BI730|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLLPAYFSVTYGAGGSTRSRTLDIVQALSA
RGTTEIAPHMSCIGDDKSEIAELLEYYKTLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
YIREHSGDHFHIEVASYPEMHPQARSFEFDIDNLVNKYQAGANASITQFFYNADSYLYLR
DKLEKRGIDTVAQPLVAGIMPITNSSNLLRFADSCGADIPRYVRKQLTDFGDDSKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLTA
>A0A2E0PK97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISDKIKEYKKQNKVFYSFEFFPPKTDFGMDNLYSRIDRMSALGPAYIDITWGAGGSTA
ERTLSMSKTIQKYFGLDVMMHLTCTNMNAKSINDVLLEAKESNLTNILALRGDPPDGSEE
WQKKNQPFNYGVDLVNYIRKNFNDTFFIAVGGYPETHQEQSDADLDIDYLKEKVDAGVDM
IVTQLFYDTDKFFIFRDKCLSKGIDIPIIPGVMPIHNYARFRKFTEFCNVSIPKNILKKL
GPIKNNDANVIQYGIEQRSIMCEKLIKEDVPGLHFYTLNLEHSVKEILHSIGLTSDQMQN
RDLPWRQSSDEDRKSSEDVRPIFWSNRPVSYLARTENWDDFPNGRWGDISSPTFGELNQY
HAIRAGSKSDGVRNKRKKIWGNPKSIEDVSNVFVSFCKGKINALPWCESKLAIESDKIAN
ELISLNELGYFTINSQPNVNGAPSDDPNYGWGAEGGIVYQKTYLEFFTSKSNLNRLIKKI
KKNKNISYQAVNISDDLISNISKDNVNVVTWGVFPGEKIKQPTIVDARSFMIWKNEAFSL
WIDDWASIYXXNTXSXSLLKKIYESYYLVXIVDNDFINSXLLKLILKK
>A0A6L9M0M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio sp. JC047|TrEMBL
MRIIDLIHEREGKPFVSFEFFPPKEEAAMPGFYDTAKQLKALDPLFVSVTYGAGGGAQDN
TLGIVSGLQKDEGFETMSHLTCVQASEDRIAGYLDQLGAVGSSNVLALRGDPPKGGSSTF
VPDNERFKHASDLIEYIREIHPEICIGVACYPDPHPESPSVREDLNWTAHKLELADFATT
QLFFDNRVYFELVEKLADKGVNKPVIPAVLPIPSVQSAKFILGLCGAMIPGKFLLALEKA
DAEGGVEAAAAVGRDFARRQIEDLLAKGAPGVHLYTLNRAEHCLKVMEGLTF
>A0A2D9PIN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MNISTKLDEYNNQGKTFYSFEFFPPKTDFGLDNLYSRIDRMASLGPAYIDITWGAGGSTA
DKTFEMSKTIQKYFGLDVMMHLTCTNMPSDSIKKILSDAQKNNISNILALRGDPPDGSSA
WKKNDSGFNYGADLVKFIRKEHGNNFFLGVGAYPETHQEQKNADLDISYLKEKVDAGADI
IVTQLFYDVENFLLFRDKCSQAGINIPIIPGIMPIHNYARFIKFTQFCKVSIPNSVSDAL
ELIKNDDSSVIDYGIEQASNMCEKLIEEGVPGLHFYTLNLEHSVTEILSRLGLVSTHKSN
RVLPWRQSTIDQRKLSEDVRPIFWSNRPISYLTRTETWDDFPNGRWGDISSPTFGELNQY
HAIRAGSQNDKVKARRRKLWGEPISIKEISDVFVSFCKGKINSLPWCETPLAFESKQILD
DLVALNQEGYFTINSQPKVGGLPSEDPNYGWGAKGGKVFQKAYLEFFTSKDNLDRLVLRL
DELNDISYQALNFDGDLISNLSENNVNAVTWGVFPGQGILQPTIVDARSFLIWKDEAFGL
WINDWASIYKTNSDSYNLLHQIHDTHYLVNIVDNDFIDGNMIKHILKK
>A0A7Z9WAY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVNEHIEQSNSTRFSYEIIPPLRGRNIQIILDMVEDLKKFNPPFIDVTSHSSTPEPYTN
GKKVLKRKRPGTISICGIIQNRFNIDTVAHLICNGFTKEETEDALIELSFLGIQNIIAIS
GDGNPKKIVDDGKTINLNSLHLVQQIKDLSKGKYLNEISNSSSIDMCIGVGCYPENHSFS
NDFDKEINLLKQKIDSGATYAVTQMCFDNKKYFSFVDKCRKENINIPIIPGIKILDKPRQ
IESLPRMFNINLPSELEKEASENIQHIREIGTRWAIKQSEELINAGVPVIHYYLMNDTSC
MLDILHHLHK
>A0A2D7MFX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRFRDKIKKPQRPVVSYEILPPREKDGTLNTYAETISSLLSQTHIDAINIPEVREEEGRG
ERPVSNQNRGEPREFGRLLQDIVGIEAIINRVVVHNSYDNQLKWFEETHKVYEIENMIIV
GGESSKINYIGPTVNEVLKAVSYRYNSKGGDIFCGGIAIPSRDNESKNLIKKSSFGSEFF
TTQVLCDSENIIKMIDRYQSRCNEKNTFPRRILLSFAPISSMKNIEFLKWLGVEIPKDTE
KYLMGRPGSMAERSLDIAIEVMNQILNHIIEQKLKVPIGLNVEHIMSYNFQLSVEMLQEL
AKIYREFCIKSNHY
>A0A1C3TS56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas translucens pv. translucens DSM 18974|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKTYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQASDALSDLRHFKAKVEAGADGAITQYFYNADAYFHFVDA
VRKLGVQVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQALGDDGDAIREFGADLV
AALCQRLLAGGAPALHFYTLNLAKPTISVLSRLE
>A0A2T2Q7M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. MOS003|TrEMBL
MTDLTIPARADGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTPYSSHPDGYQNSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLQAKVDA
GAARAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDDDSETRKLVAATVAAGQVQKLAKNGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A5E7BVY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKADLRGLLSQYQEAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQSFG
EEVITEMCERLLQGGAPGLHFYTLNQADPSLAVWNNLKLPR
>A0A3N4JZ67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Choiromyces venosus 120613-1|TrEMBL
MDKVVDKIAALPPREPYHSLEFFPPKTSMGFQNLQARLERMARALRPLFVNVTWGAGGST
ATKSLQLAEICQRQLGLTTVLHLTCTNMSQAVLDETLETAKEIGVRNILALRGDPPRSDD
YHNTPCDGTSNGVGKEFEYAIDLVKYIREKYGDYFCIGVAAYPEGHVEGASPEKQDPLFD
LPFLVEKVKAGADFIMTQLFYDTDKYLWFEKLLREESSGVLSELPIIPGLMPIQNYSMLK
RITKLSGASLPADILRRLDDVKGDDEAVKRVGIDIVSEVIEKIKAANLSGPRGFHFYTLN
LEKAVSFIIERTDLIPPPDESVLEEIEGPVVNGVNRRDRRTSSVTSDPHNRVIVDDSSSL
QSSRLANALEAGFLKPPEQSRPPEVALAISEGEGALGREATWDDYPNGRFGDARSPAFGE
IDGYGPSLHLSQAQAIKLWSYPVTKQDVSDIFVRHIKGELEAIPWSEQGLSAESKIIADH
LVKLNQKGFWTVASQPAVNSAKSTDETFGWGPKGGFVFQKAFVEFFCSLEDWEILKTKLE
GVEDISYYAANKAGDYAASVPLDGDAMHAVTWGVFPGKEYKEFPHPS
>I3U8D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Advenella kashmirensis (strain DSM 17095 / LMG 22695 / WT001)|TrEMBL
MSSFSDEAFSLEFFPPRDQVSRERLVGTAKQLMAMHPRYISVTFGAGGSTRDGTAETVSM
FSQLGCEAAPHLSCIGASRASLIQLLDQYKAKGIHRIVALRGDLPSGMGGNDSELPYASE
LVRLIREHSGDWFHVEVAAYPEMHPQADSPEHDLDNFVTKVNAGANSAITQYFFNADAYF
DFVDRAVQRGVSIPIVPGIMPITNHTQLLRFSQMCGAEVPRWIRLRLAQYGDDKASIRAF
GADVVTQLCQKLIDGGVPGIHFYTLNNAEATLAIWKNLRY
>A0A367FU58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia obeum|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPGTIEHLMKYRPEYISCTYGAGGGNVGANRE
VCQMIRNAGTVPVTHFTVIKNTKEGIRQQLEQYLADGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A3M1JRM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIEFLEKANSTLFSYEIIPPQRGGDIRQVFRLVDELIQYEPPFIDLTSRSAEVYYEDL
PDGSVRRHIKRKRPGTIGLSAALKNRYSVETVPHILCSGFTQQETEDALIELAYLGIDNV
LAVRGDELRKRLPSQNKTYNTYAVDLVKQIVNMNQGIYLEDLVDAHPTDFCIGVGGYPEK
HFEAPNLETDLSNLKAKVDAGADYIVTQMCFDNSAYFRFVEACRGIGIDVPIIPGIKILT
RETHLTSIPRNFFVDIPNALVEKVRGQDRETVYREGLNWALNQVQELVDAKVPCVHFYIM
SSATEVAQVVSQFK
>A0A248KE41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella bongori serovar 66:z41:- str. SA19983605|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A317XIE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Testicularia cyperi|TrEMBL
MSTDSVPVKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADLGPE
FVDITWNAGGRTSDLTSSLVKTVHTYIGLETCMHLTCTNMPREKIDTALREAKEFGCRNI
LALRGDPPAGQSEWEPHAAGFTRAQELVEYIRAQYGDYFAIAVAGFPEGHPEATEGAEKE
LQHLKEKIDAGADFIFTQMFYDFDIFAQWVKDVRAAGITCPIIPGVMPIQTYGGFQRATD
RFRTIVPQYFHDALDPVKDDDQKVREVGLRLVGDMCKKIVGSGLGISGLHIYTMNLEKGS
RMLLDYLGLTPSVNQVSPLPWTPSLTPKRREEKIRPIFWANRAKSYVNRTETWDEFPNGR
WGDARSPAYGDFDAYGVKLRYSTDEAKEMWGTPASLEDVKDLFKRFCAGGVKALPWSETG
VARETSVISDKLYRMNELGFLTINSQPAVDGAPSDDKVHGWGPKNGYVYQKAYLEFFVSP
ADLDALIARIEADPQITYHAVNCQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVESISF
LAWKDEAYEIGRKWAKVYDPNSESRKLLDSIFGSYFLVNVVHNDFKAADAIFEPFLQSAN
GSAAAATANGILSGVKANVTETVKQATSAVSNLANGAANGASVSTI
>A0A327MWP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQERRYSFEFFPTKTDAGQEKLLATARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEEDVANFVRKANAGADSAITQYFFNADCYFY
FVERVQALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A5E7WP22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSEDRRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A0M7ARN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium alexandrii|TrEMBL
MTVLSSRLSRGVIKTPITASFEFFPPKSEKMGETLWETVQRLAPLNPSFVSVTYGAGGST
RERTHKTVERILNETDLAPAAHLTCVGSPKAEVDAIVKDYWDLGVRHLVALRGDPLAGIG
AVYEPHPEGYAYATDLVEGIKKIANFDVSVSGYPEKHPESGSWQKEIDNLKRKVDAGADR
IITQYFFDNDLFDDYLDRIAAAGINIPVIPGILPIHNFEQTMVFSAKCGTSIPEWVARRF
ACLQNDPETRKLVGVAIACEQVMDLVDRGLTDFHFYTMNRADLTYAICHMLGMGQQGTEK
VAA
>A0A7G8ZQ40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphobacterium sp. CCMP332|TrEMBL
MKVTEHIKNAKDTLFSFEILPPLKGQGVKSIFDAIDPLMEFNPPFIDVTYHREEIVYKKK
ANGLLEKTVVKKRPGTVGICAAIMHQYKIDTVPHIICGGFNKEETENALIDLNFLGVDNV
LVLRGDAPKSDRKFIPEENGHAYALDLLNQVKDMNEGKYLDEDLKHTWKTNFCVGVAGYP
EKHFEAPNMKLDINFLKQKVDQGADYIVTQMFFDNSKYFEFVDTCKSNGINVPIIPGLKP
ITALSQMTMLPSVFHIDLPDELVNELSKCKDNASAKEVGIEWAIQQSKELKEKGAPCLHY
YTMSKSEATRKIAEALF
>A0A838S954|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirales bacterium|TrEMBL
MHISEVLRTHNPAISFEFFPPKTERTFQELFEAISALMPLKPAYVSVTYGAGGSTRERTH
DLVVKLKRETDLTIVSHLTCVGSGRQEIHQILSKYQASGIHNIMALRGDPPKGCTDVQIP
EDGFQFASDLVWFIKQQFPEMGVGVAGFPEGHPGTPNRLQEMDNLKRKVDAGADYICTQL
FFDNRDFFDFCERCEVVGIKVPIIAGIMPIVSRKGMARMSELALGARIPAKLLRAMDRAE
NDVYAEGVGIHWATEQVVDLIDHKVKGIHFYTLNKSKATLKIYESLGIQSSESLQHPVE
>A0A7C5ZCC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldicellulosiruptor owensensis|TrEMBL
MKKSFREFLKEQSIIIFDGAMGTELLNRGFSVDFPLEWANIANPELVKQIYRDYILAGAQ
CIETNTFGANECKLKIFGFENEVERINRSAVRIAKEMADDKVFVIGSVGPLGKPVGSGFE
IDARRAKEAYKRQLYFLLDEGVDAIIFETAASTHEVQIAIEALKELNDKIPYIIQFSFTR
ELTTIYGEDIYRVIEFLKFTDADVVGLNCGNGPQKTLEALKIFSQHLKGPFSVQPNAGYP
QMIQGRPVFSTPAEYFAWFAPEYVKLGAKIVGGCCGTTPEHIKAIKDKVKEFLPSIEVEV
VERKEEQKTVLKDTPSEFSQKLGKKFIFTVEISPPKGIELEKTKEGVKLLKEAGADTVNI
ADSPMARVRISPIALAHILKEELDMESILHFTCRDRNLISLQSELLGAAALGVKNVLALT
GDPPSIGDHPQAKPVFDVNSEGLVLILSRLNSGTDYMGNPIGKATNFTIGVALNLNADDL
EKEIEKLKHKIENGAHFIETQPIYEPETLERFLEKVNFSLPPILGGILPLRSSRHAEFLH
NEVPGITIPDKIRERMRSSKEPAKEGVEIACEIVEKIKHMVSGIYIMPPFEKYEMAVEII
KNFKY
>A0A7H0KA57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium wankanglinii|TrEMBL
MFEASSSTRVSASAPLDREGAPLIRRPRPKRQRTALSFEIIPPRPTDDAAKLDQLIAGLA
EYNPDYVSVTSSRRSEWLEGTAGVISRIAETTDLRTIAHLACTAGTRDEMAEWVRVLMDA
GVRGFLALRGDLPETGLPADHLQYATDLLNLIQDVQEEEAFRLAAGKLALSVACYPKGHA
ESRNADHDLDVLLTKQRLGADFAITQLFFEAQDYLEFVEVARLAGVRIPLIPGIMPMTSL
KRVRRMGELSGLEVPEGVEKQLLDAEDEYEAGMQLTANLAREILDAGTGGLHVYTHNNLA
VTRDFLDRIGIDKGQQ
>A0A447Z1X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus delphini|TrEMBL
MSRLLNALKNNILVADGAMGTILYSEGLDTCPEAYNLTHPDKVEKIHRSYIQAGADVIQT
NTYGANFEKLQQFGLEHQVKAIHQAAVAIAKRAAGPDTFILGTVGGFRSTKQGELSLSAI
QYHTDIQVDTLVAEGVDGLLFETYYDDEELLNAIKQTRQKYDIPIIAQLTASNTHYLVNG
KEINSALQQLVKAGADIVGLNCHHGPHHMKRTFGHIELPNNAYLSCYPNASLLDIDQQTF
KYSDNAQYFGETAEQLIQEGVRLIGGCCGTTPDHIRKIKTAVQGLKPIQEKKVIPIHQKQ
TSEAPKPTRQNLATRVRERPTIIVELDTPKHLDTTKFFQNVKALDDAQIDAVTLADNSLA
TVRISNIAAASLIKQQYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVHEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGVNTDGDTLKVATQFNIAGGFDPHVSNIKAAVRK
METKIKSGMHYFITQPVFTKEKIVEIYEATKHLDVPIFIGIMPITSYKNALFLHHEVPGI
KMSDDVLAQFEAVADDRQATYELSLSLCKSLIDTVHTYFNGLYLITPFERIDYSLELAAY
SKSITTSHQEAIL
>A0A7G8ZHK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphobacterium sp. CCMP332|TrEMBL
MSHQPTPFTFGRTSAPTVSFEFFPPKTDAMEARLWETVEKLEPYQPDFVSVTYGAGGSTR
ERTRNTVKRILTDTRLKAAAHLTCVGATRSETTDIIRDYKAAGVDHIVALRGDAPEGVGE
AYTTHPGGFECTSELVRAARDAGVSQVSVGCYPERHPDSPSFEHDLDVLKRKIDAGATRA
VTQFFFDPDVFFRFRDQAVAAGVNVPVIPGLMLQSNFNGLQRMANLCGASVPESLPPLYD
GLDDDPETRDLVTANVVAKLARKLEKGGAEHFHFYTLNRASLAICLVRLLGVRALAEAA
>A8T8T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. AND4|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKTATGLVAAPHLTCIDASRDELIRIADDYWHNGIKNIVALRGD
IPAGGGAPDMYASDLVGLLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDEDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVSV
>A0A426V1B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycomyces terrestris|TrEMBL
MTLGTPSVMPVKAAKIGDLLRSGEPKFSFELFPPRDEQAEGVLWRTIRDLERLGADYVSV
TYGAGGSTRLKTVDTTDLVNAETTLLTMAHCTAVDHSVAELRNLIGHFANVGVRNILAVR
GDPPGNPRADWVRHPEGILHARELVELIKESGDFSVGVAAFPDGHPRDVDWETGVRYFVE
KCRAGADFAITQIFFDVEDYLRLRDAVAAAGCDVPIVPGIMPITNIKQIERFAVLTGMVF
PEALAERLRAVEDDRDAIRDIGVEVATEMGSRLLAEGAPGLHFTTLNHSRSTRRVWQNLR
G
>A0A1I3DHF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio sp. OR37|TrEMBL
MLKDMFDRDSSLSFEVFPPKKESDFSNCYSILDSLATLNPDFISVTYGAGGSNSKKTVEI
ASYIQNTLHTDAMAHLTCVGSSADDILAVTDELNKVGVNHVLALRGDKPRDMSEEQFSKR
IFPHATDLIHFLNTNTSLDISASCYPEKHPEAISMDSDIAFMKMKQDMGAKMFISQLFFD
NTDFYRFVERAKNAGITVPIVAGIMPITSAKQIGSTVTLAGSSVPKKLADICARYGETPD
DMRKAGIEYAINQINDLKRCGMGHIHIYCMNKPKMTAEICEAIK
>A0A3B9RTR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerochaeta sp|TrEMBL
MKVIDILNQAKKPLFTFELVPPLKGGNAEVLLDTVRSLSLFEPAYINVTNHQAEVVYVER
PDGLLERRTVRKRPGTIALSGLIQHTFNIPVVAHLICGGMRSEEIEDALLELNFLGINNV
LALRGDPPHGQKRFVPIKGGHEYSSDMVTQIANLNREIYLDESLVNGDKTNFCIGVAGYP
EKHAEAANRLSDLEHLKHKVACGAQYIVTQMFFDNSVFYRFVQECRQSGITVPIIPGIKP
IGSKRDLATIPQTFHVDFPPELVELLEKAKKLSEVKEVGIYWCKKQAKDLIEQGVPGVHF
YTLGKAEAVSQVVRDVY
>A0A532BWF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPRRLREVLDQGQFAVTIEYNPPKGTNISSVLENAKQLVGRVHGVNVTDNTAAVVRA
GSLSVCRLLYELGHDPVMQMTCRDRNRIGIQSDLMGASMLGIQNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGRDMAGNKLDGSTAFTIGAAVTPEADPLGPMLAKFEVKV
KAGAQFFQTQAIYHPEQFASFMKAVRPFKSKVLAGILVLRNAKMAEFMNANIPGVSVPQE
MIDELKAAGPERAEDVGVDIAVRTIKAVRPYCDGVHIMAIKATHRLADILTKSEVG
>V4J9G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp. PB-SRB1|TrEMBL
MSFAKRLAAREFVVLAEMHTPKGVNITRLVNDARRIKGRVDAVVIPDMDNGIMRMSSLAG
GVLMQQQGVEPIIHLYCRDRNRLALQGDILAAHVMGIQNLLVTHSEPMDQSDHREAREVY
DLDELALVQAIDGLTRGVDLGGFELDGAPAFTTGCTIGSYADEAALDNELTAARAKIEAG
ARFIIAPAVFDLAGFKSFMEKASALAVPIIPTVFLIKSLAIAQYIAASEPAGSISSPIFS
MRRPCRLPTYLLWKEDNHAKNR
>A0A437D871|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzias javanicus|TrEMBL
MNTEIPSSKQEREFLFPSVSERITVAGSVPAAFASVPVKGSPAARAARPAACLRCTGVHP
TVRVRGRSRGRSGRGASSAVMVNQRVEAGWQSCRSDSSGGSNSSGESSKDSSRCSTPLPD
GDRADRLRDKMRRRTESGDRWFSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPA
GDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTREKITGYLAKAKHLGLKNIMALRG
DPIGTDWEEEEEGFNFAVDLVKHIRSEFDDYFDICVAGYPTGHPEAESYRDDLRHLKEKV
DAGADFVITQLFFRADTFLKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLQVPE
DITKVIEPIKDNDAAIRNYGIHLAVEMCSVLLESGTVPGLHFYTLNREVATMEVLRQLGL
WLEDPRRPLPWAVSANPKRKVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFG
ELNDYYLFYLKSKSSKEALLQMWGEELKNEQSVFEVFTSYITAQPNQSGHKVMCLPWNDD
PLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTS
SENVTALLKVLKKYEPRVNYHIVNVHDQNLTNAADMRPNAVTWGIFPGREIVQPTVVDPV
SFMFWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWQVIDD
MFELLDAPPEPFHTETA
>A0A1I4UVM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pleomorphomonas diazotrophica|TrEMBL
MRFSHNIGALDLGVSFEFFPPKTEKMEEALWAAITRLAPLGPRFVSVTYGAGGSTRERTH
ATVARIVRETNLKPAAHLTCVGASRAEIDDVVRGYYDAGVRHIVALRGDPAGGLGTRYQP
HPDGYASTPDLIAGIKAIGDFEISVSAYPEQHPESPDVATDIAILKRKVEAGATRAISQF
FFDNDKFERYVDRVRAAGIDVPIVPGIVPVVNFEQSASFAKKAGTSVPAWLAHRFEGLEN
DPATRQLVAAAVCAEQVMDLIDRGFRNFHFYTMNRADLVYAICHMMGLRAKTEPAVAVPA
>A0A4V2T3T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serpentinicella alkaliphila|TrEMBL
MNRFKEKLLSKQFLVTVELEPPKGINTEKLIESVNQLKGIVDAVNITDGPMANMRTSAIA
LSYKIKKETDIDAIFHLTCRDRNVIALQSELLGAGVLGINNLLILTGDEPKRGDHPKATP
VFEVDSVGLVGIVNTLNKGYDMAGTSLNEKTNFAVGVAANPTALNLNLEIERLHEKIEKG
VDFIQTQPVYNPEDLAIFMDKIKYFKVPVLAGILPLKSYKMTQHVSNNIPGINIPEWTQK
RMESGGRAEGVKIAAELVKDLKNISKGIHIMPLGDTNMVIEIIEQSKLK
>A0A2A6KFL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium hidalgonense|TrEMBL
MALNNEERGRNIGISFEFFPPKSEEMEGQLWQTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAISDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGISIPIVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIDDLVRRGLHEFHLYTMNRSPLVSAVLDNLGLSRRAAKSAGAAA
>A0A4Q8MLY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp. JR1-6|TrEMBL
MAHIDENPLGPHLPLDPLPGHSSLGRLERVLRRGEFAVTTELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAAMG
VTNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGV
GPMASAKTAKWIRSNVPGIHIPDSVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEIVHDSGVLKGRRPWKREPNPVDQLVAERIERTREGVEQNQQQMAEIAA
HHPH
>A0A7Y9IEW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microlunatus parietis|TrEMBL
MDLARMISTGEREFLLFAITPPRASTSPERMAAIGEATLSRLRSVDPDGVVLYDIADEND
RNPDERPFPFLPTVDPADFLADQLSAWQKPAIVYRSVGKYAEPDLETWLATQPTDRILSV
LVGSSSSRNIGQTSLRSAYAMRETVRPELIIGGVVIPERHQARGDEHLRMLEKQSAGCSF
FVSQVLYDVNAAKNLVSDYRDVCEARAIRPRPIAFTLSVCGSIKTLEFLTWLGVQVPNWI
QRDLTRSEDTLAASYEHVRAAAFDMLTYCRRLEVPVGLNVESVSTRRVEIEAAVRLADEV
KAALRR
>A0A8D2KD28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Urocitellus parryii|TrEMBL
MWASEAGSMRWSVPPSISRRRAMETGGLGGPTAHSEGSSSGSESSRDGSRCSTPGLDPER
HERLREKMRRRMESGDKWFSLEFFPPRTAEGAANLIARFDQMAAGGPLFIDVTWHPAGDP
GSDKETSSMMIASTAVNYCGLETILHMTCCRQRREEITGHLHKAKQLGLKNILALRGDPI
GDQWETEEGGFSYAADLVKHIRSEFEDYFDICVAGYPKGHPDAESFEDDLKHLKEKVSAG
ADFIVTQLFFEADTFFHFVKACAAAGITCPILPGIFPIQGYSSLRQLMKLSKLEVPQEIK
DVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATTEVLKRLGLWTE
DPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELR
DYYLFYLKSKSPREELLKMWGEELCSEESVFEVFAHYLSGEPNRHGHKVTCLPWNDEPLA
TETSLMREELLRVNQQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRET
VEALLQVLKKYELRVHYHIVDVKGENVTNAPELRPNAVTWGIFPGREIIQPTVVDPVSFM
FWKDEAFALWIERWGKLYDEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFE
LLNRPAQSERESEGL
>A0A1W9W0X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium 4572_78|TrEMBL
MKFSEMYAQSYPILSVELFPPKTEKGWGNLYRRLSHLKGLPLQFVSVTYGAGGSIRDRTL
ELTQKVRESIGVTSVPHFTLIGAGKEQIRKFLHESIAQGAENIVALRGDIPKNTLDFPIP
SDGFQHANELVAFIRNETDALDIGVAGYPEGHTECRDLVTDMENLKRKVDAGATIVITQL
FYDNTDFFRFRERAVKTGVTVPIVAGIMPIVKFSQIKRITSMCGASIPKHLYDTLTKYDM
DSAEQRMAGIEYAINQARNLLENDVVGLHIYSLNKWRTVTKLLEGVQDLIEQEN
>A0A7W9JYM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. 3498|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
RFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQANDALSDLRHFKAKVDAGADAAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAEAIRDFGADVV
ATLCQRLIDGGAPGLHFYTLNLAKPTTSVLARLRGAIAAG
>A0A829J081|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli KOEGE 73|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>F8FC39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus mucilaginosus (strain KNP414)|TrEMBL
MKPGLREALRSQVLVGDGAMGTYLYQMGFPIGISYEELNLLKPDVIMDVHRRYYEAGARL
IETNTFSANREKLSKFGLEGEVEAINRAGVELARRAVGEDAYVVGAVGSIRAGKRKNVRT
NKVREDLREQISILCDTKVDGLLLESFLDLDEMLIALKEVRRISDLPVICQFATEGAGVT
QDGVPLKEAFAKLLEAGADVVGLNCRSGPNGLLRSLEGAAAAEADHPPYSVFPNAGLADY
VDGRYSFPATPQYFGETARRFADLGTRIIGGCCGTTPEHIAAVAGALAGYVPNPEAAKRA
AAAPAAEVAERAAAGAGAEVPTEPSIVDLVRQRHTVIVELDPPKDLDIGKFMEGTEALKK
AGVDALTMADNSLAVTRMSNLALGSIVKERTGIRPLIHIACRDRNLIGTQSHMMGLHALG
IDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKKQANFIIGAA
FNPNVKYLDKAVQRLERKVEAGADYIMTQPVYNAELIEQVYEATKHLSVPIFIGIMPLAS
GNNAEYLHNEVPGIQLSDDVRKRMSGLRGEEGRAMGVQIGRELLDAAMRRFNGIYLMTPF
LAYEMTVQLTEYVWEKAGRRHLSPLPK
>A0A850D3H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbellaceae bacterium|TrEMBL
MPGFELICEVEPPTRPDLKKVRHQIGVLSAVADGFLIPDNHIGRATVSSVAVANEVQLMG
ARGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDDPAEGARTSQLTVRRMIEQTRE
TTYPGCNPFKVGAATRLRPVPRWKAEADFLYVQVSYDLDELLRWRESVRLDIPVYAGVMV
LASARMARNLAGLSQLTIPDALVEAVEQDRDAGVDHACEQILKIRDSGAFEGVHLIPVSR
YRQVAARLEREL
>E3D9T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis (strain ATCC 14019 / 317)|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIHSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKISEPVLAMIER
>A0A317E0C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zavarzinia compransoris|TrEMBL
MTLDPLGPLNVSFEFFPPKTPEMEDALWRTVRRLEPLNPGFVSVTYGAGGSTRERTHATV
KRLVEETRLKPAAHLTCVAATRDEVDAVARDYWQAGVRHIVALRGDSQVPGAPYQPHPGG
YDYAVDLVAGLKRIADFEISVAAYPEVHPDAAGPGADLDNLKRKIDAGATRAITQFFFDN
DVYFRFLDRVLAAGITVPVLPGIIPVSNFRQIAKFAAATGATIPAAMARHFDGLDDDPET
RKLVAVAVAAEQVRGLAAAGIADFHFYTLNRADLCFALCHLLGLRAGA
>A0A402AD43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyobacter kobayashii|TrEMBL
MGLIQIIRGFTAGHDAAGSSIGAKASFHIGCALNLNMTDEETDREIEKYQRKIEAGADFI
MTQPIYELAPLERFLSRAGKPPVPMLLGYVMLHNSKHAEYLHNEVPGITIPEEVRNRLRA
AGEHGNEEGLRIAQELLAEAYTHIQGVYLLPSYRRYDIVSELIKTLRAQQLA
>A0A416H7E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. OF02-6|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVQLLESGVDLGGNPLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAEI
>A0A2E9I7L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mameliella sp|TrEMBL
MQRPEISFEFFPPKNIEATFRLWDAVQVLSPLAPRFVSVTYGAGGTTRDLTRDVVATLHK
HSGLRTAAHLTCVNATRAETLAIADGFAEAGVTDIVSLRGDPPKGSAGFEAHPDGFANSI
ELIEALAETGKFTQRVGAYPDPHPEADSQQASIEWLKRKLDAGATEALTQFFFEADTFFR
FRDDCAKAGIDTSKLVPGILPIENWNGARRFAESCGTYIPAWVSDAFEKAKRDGREDLLA
TAICSELCTDLIEGGVDKLHFYTLNRPELTRDVCFALGVTPEVNFEQVA
>A0A0S8BDW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonas sp. SG8_28|TrEMBL
MTATLRERIADDRVHVMDGAMGTVLYSRGMFVNVCYDELNLTHPDLVREVHTAYLRAGAE
ILETNTFGANPVKLSGFGLDGETEAINRAAAALASEAAGSSASIVGSIGPLGIRIEPFGP
TAREEAVAFFRRQVKGLLEGGVEGFILETFSDLEELHTAYVAVRSTCDLPIFALMTVDES
GSTTYGTDPEKIATTLAQWGADVIGLNCSVGPAVMLDALERMAEVTDRPLAAIPNAGLPR
LVGDRKIYLSSPEYMANYAVRMIRAGARFVGGCCGTTEDHIKRIRDEVATMQPRQPHVVV
ARQSIVAPEGVEPVALAERSTLGAKLAGGDFVHNVELPPARGWRAEALLAQARALHELGV
DCVSILDGARARSAIAAIPAAVVIERDVGLETMVHYTCRDRNMLGMLSDMLGAAAAGLRN
ALLITGDPPRFGPYPESTAVFDIDSIGLTNVVYRLNHGIDPGGNPIGEPTRFVIGVAANH
MAVDMGLELKRLYWKADAGADFIVTQPVFDVGTFDAFVRSTEEFRLPVLAGVWPLTSVRN
AEFLANEIPGQRVPPSVLARMRKAQERGADAALEEGLCIAREIVAAVRGMVRGVHLSLPR
GPPEVARAVLSDA
>A0A2N2BAB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-5|TrEMBL
MMIKDYIKDQVLLMDGAMGTYFAELTEGHYTLSEPANISKPGLILDIHRAYIEAGAKLIR
TNTFAANPYTLYRSFDEVKKIIIAGIDIANEAVKGTDCYVAYSIGPIGEPYDIEDYEIES
TYRKLIDIGLLKNVKIILLETFSRIDQVNQLVEYIHEHGPNIQIMTNFTVNQHGYTKVGV
NKEKIIQQTRQQDLVTTYGFNCGIGASHLLSLIKTLDFDPSKMAAVPNAGYPDQQLERTV
YQSNADYFADTMIKICEEGVRIVGGCCGTTPEHIRKIRERLNTLDFGEVKSISRMKRKSL
PLKPLHNSFREKLEKNEFVVAVELDPPFKMDMSLIISSAHLLKEVGVDIITFADSPLGRT
RADALLVAAKIKQLTGMEVLPHVCLRDKNLIALRGGLVGAHLSDIRNILIVTGDPIPSDD
RDEVKSVFNMNAISFMQYVTEVNSELDSDTFYIGGALNPYTQNMEVTLERVMKKKEAGAS
YLLTQPVYNEAGIEAIRKVRDRTGIKILGGIMPLVSLRNARFLHYEFPGIIIPDDVMSKF
DDTMTKEEAEKVGVELAVTLAKKMKPHVDGLYFMTPFNRATMIEKIIKKLDVR
>A0A7L8SDD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. 38R|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYVRKPQFCSVTYGAGGSTHQGTFGAVQEILAE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFATKMKAGADSAITQYFFSPEAYFRFVDD
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLQEGGAPAIHFYTMNQSAATLAILERLD
>A0A847PWX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Fermentibacteria bacterium|TrEMBL
MSSFRQMLADNRVLVFDGAMGTMLYEMGAAGGSCYDALNLTRPEIGSSVLRDYVEAGADV
ITTNTFGANPIVLQRYYGLGARAADINTEGARIARAVSGGRLVAGSVGPLTRPAEVFDDL
TDSEMTEAFRVQIGALVAGGVDLVVFETFNDPRELAIAVETLRGMSDTPCVAMLTFLEGG
QTLGGLHPLHAGHILDSLDADVVGVNCGTGPMDMLKVVQKLCQATGKPIIAMPNAGLARF
ERGRFIYPSNVEHMGLYAARLVSAGCICVGGCCGTTPDHIRAVSAAVRDLTPGRRKRVKV
TAQGIDPAPQSEVRVETTLSQMLNRRTVLSVEVDPPRGPDGSKTLARLRRLKGLGVDAVN
VSDGPMARLRMSPAAFSAMVQRELNLEVIIHATCRDKNILALQSDLLGFAAMGLRNVLAL
SGDPPSIGDYPFATAVYDVRSEGLIRIIDSLNHGRDLLGNRLNANAGLFCGTGAPSAPSD
PDSEARLVQRKAASGLRFVQTQPVFDLERFSKFLEILRPLGLPVIAGLMPVLSASGLEYL
ENEVPGIRIPPGMLELMRSAGGEEAQREAGLSQARSMLASLRGLGVHGICIMPALNGYDV
VEDILR
>A0A7K2RR63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8367|TrEMBL
MRPTFSFEFFPPKTAKGEQTLWQALRRIEPLAPDFVSVTYGAGGSSRERTVQVTQRIVAE
TTLRPVAHLTAVDHSVAELRHIIGQYADVGVRDVLVLRGDPPGDPRGPWRPHPDGFTYAY
QLVELVRSLGEFRVGVAAFPEMHPRSPDWDTDIRHFVAKCHAGADYAVTQMFFDVEDYLR
LRDRVAAAGCDTPIIPEIMPATDARQIGRFAELSGAAFPEDLAHRLEASRDRPHDAYEIG
VAHATAMAERLLAEGAPGLHYITLNKSTATLDIHRAVLNSSRSLHVS
>A0A7C1E815|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomicrobia archaeon|TrEMBL
MPDEIYSDLMRELSEGRFVFTGELEPEKAGECEEPIAAARDLIGLVTACNVTDNPQSFAY
VNSLAASYKIQSDTGMECVYQLRCADRNRMALLSDILGASTLGIKNILALAGDHVSLGDT
PDTKPVFDLDSTTLIHLIRQMVDEGKDLRGNKIHNPPKLHVGGAAAPGAAHLKAEVAKVK
RKINVGVEYIQTQVVYYQDILDKFFNELGKTDVPVLVGIFPAKSFGAADFFDKYVAGVDV
PPDYLANLKTTKEIADKEKRKAEVDRINVEFFTDFLEYLKGTPAAGCHMMAVGYPRIIGP
LKKVME
>A0A1Q7KNR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium 13_1_40CM_3_66_12|TrEMBL
MTTTFRSLLDDGRVHVFDGAMGTMLYGKGFFLNVCYDELNLKQPRLVQEVHAEYVRAGAE
ILETNTFGANPLKLNSYGLADETEKINRTAAELARAAGGGRVSVVGAIGPLGIRIEPFGP
TSQAEAEAVFARQVQGLLAGGVDGFILETFSDLDEMHAALRAVRAASDLPVVCQMTIGTD
GLTYYGTDPDTYTKQLAAWGADVIGVNCSVGPAGVLEAVEKMVKATDKPISAQPNAGLPK
DVGDRKIYLASPEYMASYARRMIETGARFVGGCCGSTPEHIKKIRDYVASVVPRQPSVVV
SRAQVHAPAGVTPIPLAEKSRWGAKLARGALVTSVEIVPPKGVDPKPMLEQCRALKAAGV
DAVNVPDGPRAQSRMGVLPSALLIEREVGIETVIHYCCRDRNLLGMLSDIIGAHAAGLRN
ILIITGDPPKMGPYPEATAVFDIDSIGLTNLVYRLNQGLDPGNNPLGGMTKWAIGVGVNP
GATDKDRELSRFAWKVDAGAEFAVTQPVFDARQLEAFLKQVEQFQTPIVAGIWPLISLRN
AEFLANEVPGVSVPDEVLQRMRKAQEKGKEAALAEGVAIAREMFTRVKQMVQGVQVSAPF
GRVEVALQVFQ
>A0A0F2P2C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium BRH_c54|TrEMBL
MKVIEHINKAKKPLFSFEILPPLKGKGIQSIYDSIDPLIDFNPSFINVTYHREEFIYKKR
EKGYLEKIAIKKRPGTVGICAAIVNKYKVDAVPHIICGGFTKEETENALIDLDFLGIDNV
LALRGDPIKTEPAFVPEKEGHQYAVNLVKQIVGLNKGVYMDEDLQNASPTNFCIGVAGYP
EKHFESPNIKSDLKRLKQKVDAGAEYIVTQLFYDTEKFIDFVNLCRKNDINVPIIPGIKP
ISNKNQLISLSKFFHIDLPDDLVDAVEKCKDDEAVKQVGIEWAIDQSKKLVEFGVPCIHY
YTMGKSVAVKEIAKAIY
>A0A6C8LM32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Lubbock|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0Q4W689|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Leaf262|TrEMBL
MTITEADRHTGGSFKLSFEFFPPKNADMDVQLWETVEELSRWNPDFVSVTYGAGGSTKAP
TLQAVQRMISVADLPTASHLTCVDASKQDVHDVVQEFTAAGVKHFVALRGDPSTGIGTDY
KPHPQGYENAAALVRGLRDIGDFEISVSAYPEKHPESESDAVDIDMLKRKADNGATRALT
QFFFDNEIFERYMERVTKAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPAFLDERFAGL
DDEPTARARVAAEVAAEQILDLQRRGINEFHLYTMNRAPLVNAVLENVGFRPLRRSAA
>A0A2T9ZB19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium megazygosporum|TrEMBL
MSFLKTDKDFSDSGNPSFSLEFFPPKTPQGLINLKDRLARIATWNPLFGAVTWGTGGSTF
NQSMDFAVMLKSEFNIEPLLHLTCTNMPISQIDHALLVAKEKGIRNILVLRGDEPLTQTD
ALDDTPKDVGGSRFQYASELVRYIRSKDAYKNFFNIGVAGHPEGYINSNFPTDKEQDHSS
ISTSCGQGSNIGKEKVSETHKKFDKELREIMCLKDKVNEGADFILSQIFYNTENFIKWYI
KCKSIGINVPIIPTLLPIQTYSSFQRIVKLTGIQVPEKLQERLSLVKHDDKLVKSIGVEY
CIEQVNTISSMLGVANFHFATLNLEMSVSKVLTKSGLLDLTDKENLNDNSDSVANILLGQ
GFGVASSSSQDGIDKRKAQILWDEYPNSRWGDARSPSFFNETLYGQYGSMVSELGSWGVP
KTEADINELFRGYVNKQKLSLPWTNDSIEVFDTKHKAVLEKMCLNGLWVLASQYGIDGVS
SSDKEYGWGPENGYVYQRSFVEFFVRKPLLLKLAKFLNIHKKEISFYAATFGDRSSQQNG
DAFAGVSGDGNALGTGEQEDQKVHIITSRSKGKELSDELFQEDLLPSEISQVVIESKEEK
ALNIAGGDEACGYAASENSNENEEIESTVLTWGVFPHKIVQAALIDRLNFGFWSKEAIQV
WHVWSKLMEYRNRTSSGFLGQVADDVWLVNVIGNDYKHPYELFELLEKFTL
>A0A2R6J6Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QS_7_68_65|TrEMBL
MSVARSAAAMDGATDLLTDLRFELMPFDSFEGQMDRLPDGATIAITTSPQLGLDATVEWA
EKAAKQGFEVSPHIAARYVRDEEHLEEIAQRLTDAGITDVFVPGGDREEPAGEFASAYEL
LVALDDLDYDFDEVGITGYPEGHEFLDDATLAEAMKKKAPHATYIVTQLCYDPDAVIAWI
EEVRDRGVDLPVEIGIPGVMKYQRLLSISQKVGVGDSVRFLKKTTGILGFVRQLVGSRGK
YTPDDLIDGLAPYANDPEYGIRGLHIYTFNQTSDTESWRYGRLEE
>A0A6H0J0A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquisalimonas sp. 2447|TrEMBL
MGQTATATHQDTLRGCDAVARPRYELIPISGMMEQARTLPTGATITVTCSPKHGIGTTLD
AAETLATEGYDAVPHVAARLIRDHGELREILDRLSGAGLREAFIVGGDAAEAAGPFRGGL
ELLRAIHDSGRRPPRIGVPGYPEPHASIPGKEMQAAFLAKGALADYAVTQICFDANAILG
WLGQQRELGMDLPVYVGLPGVIDRTRLLGLAVRIGLGASTRVLRRQGGLASRLFGSSVYQ
PDDLVRTLAPTFDTPQAPGLAGFHVNTFNQVEATRRWMEETAEELRQWSAPRPEKTAELT
GAIEGTY
>A0A327X7J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Larkinella arboricola|TrEMBL
MAKVSDHIRRANGKTIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PEPDGTIRKIITRKRPGTVGICSAILHRFGVDPVPHVLCGGFTRDETEDFLVDLNYLGID
NVLVLRGDPAKPFDTFKPKTNGYSYASELVEQVANMNRGLYLHESDHAMTPSDFCIGVAA
YPEKHFEAVDHETDFNYLKMKVDKGADYIVTQMFFDNQKFFDFVKKCREAGITVPIFPGL
KPLSTRKQLQVLPRLFHLEMPQDLIKAVEACENDVQARQVGVEWCIQQCRELTKAGVPGL
HFYTMGKSDNVIKIAREIF
>A0A6I9HXN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vicugna pacos|TrEMBL
MDRPKPRVPAVGPCCPSRGMRASEAGSARFSVPPCISRNSAMVNEPRGNGGPNPRSEGSS
SGSESSKESSRCSTPGLDPERHEKLKEKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETVLHMTCCHQSREEITG
HLHKAKRLGLKNILALRGDPIGDQWEEEEGGFNYAADLVKHIRGEFGDYFDVCVAGYPKG
HPDAESFEADLTHLKEKVAAGADFIITQLFFEADTFFRFFKACSEMGIACPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCRELLESGLVPGLHF
YTLNREVATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGKELTSEESVFEVFVRYLS
GEPNQDGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETTEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGKLYEEESPSRMIIQHIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRAPQNERETEAP
>A0A7I6TPJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella sp. WP7-S18-CRE-03|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A2H3J3E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wolfiporia cocos (strain MD-104)|TrEMBL
MKISQKIAQADKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQKLIGIETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPMGKDE
WEAVEGGFIHGIDLVQHIRSLYGDYFDIAVAGFPQHELLPPEEFALELQYLKEKIDAGAN
FIFTQMFYDVEIFIRWVHAVRAAGITVPIVPGIAPIQTWNGFQKATSLAKTKIPQSFRDA
LEPHKNNDEKVREIGTKLVAEMCRRILQEPIGIRGLHFYTMNLEKATRMLLEELNLVPRI
QTIKPLPWRQSLTPNRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDARSPAYGELD
GYGIWIKQTKEEALQLWGHPTSVAEIGKLFAKFCLGELPALPWSDSAPSSETSVIATQLA
KLNDIGFLTINSQPAVDGARSDDRIHGWGPPNGYVYQKAYLEFFVSPELLDKLLPHIERD
ANITYYVINKRGDLRTNTHSDGPNAVTWGVFPNKEIIQPTIVEAISFMAWKDEAYELGRQ
WSKYHEPGSTTDKLITDIMETYYLVNVVHNDFKKPHAIFEPFFKAGAEHATSQNGQPPVV
LNGH
>A0A5R8QEJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystis sp. B8|TrEMBL
MFNALHPTASQNQFAISYEFFPPKTPEMETQLWQSIKRLAALRPHFVSVTYGAGGTTRER
THSIVARIVRETDVKPAAHLTCVSSAREEIDEILRDYWEAGVRHIVALRGDPPTGVGTKF
EPHPKGYANSTDLVSGIRRIGDFEISVSTYPEGHPESASIEQDLDALQAKIDAGATRAIT
QFFFDNDIYFRFLDKARARGITIPIVPGIMPIRNFKQVAGFAQKAGASVPRWLAERFDGL
DEDPETRALIAATTAVEQVMSLARAGVNEFHFYTNNRADLVFAICHLLGVRPLREKALA
>A0A5C8NNS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium terrae|TrEMBL
MPDLDRSLAAHLRDGVPSFSFEFFPPKDDAGEEVLWNTIADLEPLEPTFVSVTYGAGGTS
QERTVRITARIAEQSGMRAIGHLTLVAQSKGEIEDVLKQYAAAGIDHVLALRGDPKGGPR
APWEPHPDGMTYAIDLVELAGDLGGFCIGVAAFPEGHPDAASLQADAEVLVAKERAGAEY
AITQLFFRASDYFDLVQRVRDLGGRIPIIPGIMPILNFAQVSRMAELSGAEIPREVLDQI
EPISDDKDAVRAKGIELATQLCRDLLAGGAPGLHFITLNRSKATREIFETLRSEGLV
>A0A2V3U0G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chelatococcus asaccharovorans|TrEMBL
MAPASFRPSRHSSRPVRVSFEFFPPKTPAMEETLWTSIERLAPLKPNFVSVTYGAGGSTR
ERTHATVKRIVDETALKPAAHLTCVSATREEVDAVARAYWAAGVRHVVALRGDPVAGIGT
AYEAHPGGYASSYDLVAGLKRIGDFEVTVSAYPEKHPESPSIDADIEILKRKVDAGADRA
VTQFFFDNDLYLRYIDKVRAAGINIPIVPGILPVQNFKQAANFAERAGASMPDWLAARFD
GLDEDVETRRLIAAAVAAEQVIDLVDRGVTDLHFYTMNRADLVYAICHLLGLRAEITAPA
KTTVPASAVAAA
>A0A316V549|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meira miltonrushii|TrEMBL
MISEIIANAIKSDKPVFSLEFFPPKTQQGLSNLYTRIARMVTDLDPAWIQITWGAGGSTQ
STSLDLAGRVQAGALGPKAILESSILDSTPSTPIEDGRHELLSRNVCLHLTCTNVEKASL
DETLDRALKSGIRNILALRGDPPRGQELWVAADDRFQHATDLVRYIRSRHGNAFCIGVAA
YPEMHPDAEANETPNSEIQHLLAKQEVGADFIVTQLFYDVDNFLAWYADCRANGITIPII
PGVMPIQSYQTFRRVTSLCKAKVPQAVWDAIEPVRFDDAAVRDVGVNLTKALIEKICQST
DIRAFHICTLNLEKSTKTILQALQWLSDPKSKQNPAKATSDATKIEKASLTSNTHSQTLK
PPTNPVTTMEEAAATWDEFPNGRYGDARSPAFGQIDGYGVSLKIPPQEALRQWGRPTTNA
EISDIFTLYLNGKLEVIPWCDCPILPETNSISNELLRLNADKGAKLEESFTGKGWWTVGS
QPSADGIDSSDPVFGFGPAHGYIFQKAFVEFFSTEKDMLDLEKRIEEYNTKKGGTWLSFF
AGNRAGQFRTNVDAEQGESCAVTWGCFVGKEIVQTTIIERESFDAWREEAFGIWSEWETL
FPAHSPTKSLLQEIGQQRWLVTVIHHDYKDEGALWSFLEVR
>A0A4Y8JRE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT2-15-1|TrEMBL
MPHTSDPACRKIPFSFELYPPTSDAATSVLHATIERLAAAGPEFIAVTYGANGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSNAEASQLIREFLDAGVRSFLALRGDPPEGIREGEAF
LGDLGSAAELVQLIHRVQAERVPYREAVIPGLPAARTIKREREKVRIAVAAFPNGHPRSR
SATQDIDTLLAKQAAGANLAITQLFFHADHYLSFILRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRQATELARELIAGGAPGLHLYAFNQHE
TVLAVLDGCGLLTPTLPSSALPAPHPVKENP
>A8S2A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster bolteae (strain ATCC BAA-613 / DSM 15670 / CCUG 46953 / JCM 12243 / WAL 16351)|TrEMBL
MKIRDILAEGKPTLSFEVFPPKTEDAYDSVEKAAAEIAKLKPSFMSVTYGAGGGTSEYTV
GIASAIKEEYGVTPLAHLTCVSSTREKVHHVLGELRERGIENVLALRGDIPQDGSTPKEY
HYASELIREIKKAGDFCIGAACYPEGHVESANKSVDIDYLKQKVEAGCDFVTTQMFFDNS
ILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTYLPSRFMSIVDRFGDNPAAM
KQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A558BXB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter setariae|TrEMBL
MKVTEHLRRAEGKTLFSFEVLPPRKGENIHTLFSNIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRKRPGTVGICAAIKNRFDVDTVPHLICGGFAKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFQPHPDGHRYACDLIGQISELNHGRYHDHDEQYQPAGAEPILSTDF
CIGTAGYPEKHFEAPNFGSDIRFLKEKVDRGADYIVTQMFFDNEEFFKFERRCRDAGITV
PIIPGLKPLTTKSQLTALPRAFFLNIPETLAEAIHGAKDNAAAREVGIEWCLNQSRELMA
HGVPCLHYYSMGKSEAIRRVAAGLF
>J9YGW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc gelidum (strain JB7)|TrEMBL
MTKISKIYHTKSAPVLSFEIFPPKKETDIELLYQTLDEVNPKKLGVDYISVTYGAGGSGD
NTRTRDLAQYIQMHFGVTALHHLTGVNQTPERLRDILSKIEQAGIENILALRGDLADKTY
VNVNYPYAKDLIYGIKQFSGFNVGAAIYPEGHIDNPITGISMAGIKEKIASGADFLMSQF
FFENDVYYNMQEALKNNYIKVPVSAGVLPIISKAQAERMAHMIGSPLPARLVKIVHKYED
NPEDLKKAGIDYALEQIQDLLNHGVDGIHLYAMNQPSVLKNMLPIINQEIKTKCFVEDGI
IDHA
>A0A0M4M046|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lawsonella clevelandensis|TrEMBL
MLTTSASSVLDRIEESTSERIPFSVEFFPARTDEALEKLWASVRMFEQWGACFASMTYGA
GGSNRDRMVDITARMRRETSLLPLAHLTAVNHSRVELEQVLQAFVDNDIHNVLALRGDPP
GDPLGVWRKHPEGVEFASELVEIIREKGGVEIGVAAFPNGHFRAPTLDADTQFTLQKLRA
GASFAVTQIFFEADAYLRLRDRLVEADKEIGSRPLIPSIMPITSLKSAHRMVQLSGSRLP
RSVEQRLDKAAGSGPEENVQAVSDLGIQMSLEICERLIAEGVPALHFDTLNKVFPIADVL
RGLGIISDAELEIAKNTR
>G8QYQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerochaeta pleomorpha (strain ATCC BAA-1885 / DSM 22778 / Grapes)|TrEMBL
MKVTDILSQAKKPLFTFELVPPLKGGNAETLLDTVRQLSVFEPAYINVTNHQREVVYIER
PDGLLQRKTVHKRPGTVALSALIQYTFNIPVVAHLICGGMNADEIEDTLVELNFLGIDNV
LALRGDPPVGQKRFVPVEGGYDHSDQMVSQIIALNNGIYLDHELKNPQKTNFCVGVAGYP
EKHGEAPNLSNDMANLKRKVDCGAGYIVTQMFFDNAVYYRFVDEARKAGITVPIIPGIKP
IGSKRDLLTIPQTFHVDFPSELVDLLSQAKTLQDVKEVGVYWCKKQATDLIANGVPGVHF
YTLGKAESVSRVVKDVY
>A0A7C9B5V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter senegalensis|TrEMBL
MSLSRLSVELIPRSTEALLDDVASVKALFPAADTLNVPDLMRFPLRSWDAAALIRPHFAR
VVPHIRAIDIAPDAPLPGADQPGLEEVLVVHGDPPADLSHRTYPNSTESIIRRYKKEAPH
LRIYAAFDPYRRAPWQELEDVARKKEAGAEGFFTQPVFDLKLFDLCREWLRDETVFWGLS
PVIGPRSRSYWETTNHVVFPKDFEPTLEANIHFAQTVLRHLSQEKGRAYLMPLRVKLDQY
LPPLIEALA
>A0A7X9PMY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSIIKPARRWQPAFYPFKKEKFSARLLGRIELAVKGPVFGCRMCGNCLLQETAFICPMEC
PKGMRNGPCGGITPEKNCYVDESRKCVWYAIYERSRKMGRQKMLLEVLPPLDWYKVGTET
WGVVVRQVRKTGIWTFIRSLFLKDKIKKSEVWDSVFKTIRQPAWWMGDSEYHKPAYEEPA
SLLEKKLRNGEFVIATEVSPPLGANPAKIIREIELVRPWVTAVNFTDASSASPKMSGIAC
CKVANDLNCEAVFQIAARDTTRTGLQSAVIGSGQMGVRNILCVTGDNPRVGPSPASDMNF
VDVDSVQMLWILRRMRDEGIYLDGRKIKYPPKFFLGAATTPFASDPELQAI
>A0A838KQQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacteraceae bacterium|TrEMBL
MSPNLRELLATRVLIGDGAVGTLLGERGVGFGHPYARANLSHPGMVNDIHVEYLRAGADV
IETNTFAANRFKLETHDLEERVREVNAEGASLARKAARAAAGTGDRALVLGAIGPLGRPL
APVGPVSPERAKSVFLEQAEALLEGGADAILLETFTDLVELRLAYEAVGALGAPVLAYKT
FVEDGETLAEGLPGRAAREISSWGADLTGANCTVGPQRMVEIIGQMADAAGPVAAFPNPG
LPQLVRGQIRFSKDVDHFAEYGVKLAEAGARLVGGCCGTTPAHVKALSEALRDFRVEGTG
ARRRAVMVEQPGQAYVLAEPVSEFAERLRTGFAVTVEVDLPRGNAIEQVVEAARRLKERG
VHAIDISDGARARLRMHPVAAARIVQDEAGIEVVAHISCRDRNIIGLQADLLGAAALGVK
NILAVTGDPAQIGDYPEATSVFDTDSVGLVHILSRMNRGEDLAGNPIGEPPGFLVGASFN
PTAEDLDEEVEKLRRKVEAGAHAFWTQPVFEIGALENALERVGDDGVCILLGLMPLRSAR
QAEFLHHEVPGINIPKHVREKLAALSPEDAPKYGVEVAQRLLVAARPLIGGAYIMPPASA
PDLAGDVLEAISLPAGRR
>A0A3D8VTD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacillus trueperi|TrEMBL
MDLREALQNRTLIGDGAMGTLLYSYGIDRCFEELNLSHSEEVLNVHRAYVNAGADVIQTN
TYGANYIKLERYGLQDQVKEINTAAVKLAKQAAGENQYVVGTIGGVRGARKQAISTEEIK
RSFREQLYCLLFEKVDGLLLETFYDLEELTTVLKIARKETDLPIIAQVSMHEAGVLQDGT
PLPDALKQLEGLGADVVGVNCRLGPYHTIQSLEDVPLPEQAVLSAYPNASLPAYQDGRLV
YPTDPAYFQKSAQSLFDQGARLIGGCCGTTPEHIEAIAARVKGKQPIQDKVVPIKARTEV
RVSETKDDRHHLHEKAKKGRSIIVELDPPKKLKTERFLEGAKALHEAGVDSVTLADNSLA
SPRISNTAMASIIKQQYDVDPLVHIACRDRNLLGLQSHLMGLHALGIRQLLAVTGDPTKI
GDFPGATSVYDLNSFDLIHYIKQMNKGISFSGKNLGESTSFSVAAAFNPNVRNLNRAVGR
LEKKMKYGADYFISQPVFNEEQIIEVYEATKHIDAPIYIGIMPLTSARNAEFLHNEVPGI
TLAPEVLEKMELAGSDKEQAQAEGLSISKSLIDTALDLFNGIYLITPFLRYEMTVELTNY
IKQQTAEGERKISNGIHIV
>A0A6L3AQG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Jettenia sp. AMX1|TrEMBL
MIENRSDIKSGSNLEKLLLSGQFAVTAELGPPRGADRSAIEKKAEILKGYGDAFNITDCQ
TAVVRMSSIASGRIVLDAGIEPIIQMTCRDRNRIAIQSDLLGAAALGLKNLLCLTGDHQK
FGDHPMAKGVFDIDSVQLIHMVKTLRDEKRFQSGQELKASEPKFFIGAAENPFADPFKFR
AVRLAKKIAAGADFIQTQIIYNVKKFHEWMNMVADMGLHEKVFILAGVAPLKSAGMAKHM
KHNVPGMDVPDEVMSRMTAASAAKKGKEEGIKICLEVIEQVREIKGVAGVHVMAVEWEEA
VPEIIQQARLFPRPTV
>A0A847ALR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
DLKYLKQKVDAGAEYIVTQMFFDNKVYYEFVEKCRAVGITVPIIPGIKPIHMKNQLTVLP
KIFNIKLPQELAAELSKCKNNDEARKIGTEWAIYQSKDLVAHNVPSLHIYTYGISDNVRE
IIKAVF
>A0A844MC61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scytonema sp. UIC 10036|TrEMBL
MDNILKTTPLSSFRAAAQAGEFLVTAEVAPPKGGDPTHMIEMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQNGIEPICQIACRDRNRIGLQADLMGAHALGILNILALTGDPVKA
GDHPEAKGVFDLEAVRLLQLIQKLNHGVDCNEQPLTDGALNLFPGAAVDPQCNSWSGLQS
RFDRKLEAGAQFFQSQLITDFERLEKFMHQIAGSCNKPILAGIFLLKSAKNAEFINRCVP
GVNIPQHIIDRLAKAKKPLEEGMKIAAEQVQIARQLCHGVHMMAVKREDLIPQILDLAGV
ASIHSSGLPR
>A0A847AMV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVIDIIKNSNKTIFSFELLPPLKGNDPESIYRTIENLIDFDPKYINITTHRDEVQFQKM
SDGTVKKNIRRKRPGTVAIAASIQYRYGIPVVPHILCGGFTKSETEYVLIDLYFLEIENV
LALRGDGIKSQNLFIPEKEGHSYANELVEQIVNLRKGSYLEKDLKNNTPLDFCIGVGGYP
EKHFEAP
>A0A3D3HEI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKGPNVIDLINSSKKPLFTFELLPPLKGHSIERIYHTIEGLLEYEPAYINFTSHRNEVVL
TERPDGLLEKRTTRKRPGTIALAAAVKYKYNVNVVPHILCGGFSKEETENALIEMNFLGI
NDVLALRGDPPKGSRVFIPDPGGHKNTNELVQQISDMNRGHYLDSDLKNTAPTSFCIGVA
GYPEKHFEAPNLKSDMVNLKRKVDAGACYIVTQMFFDNEKFYSFRDALRAMGVTVPLIPG
IKPVSAMTDVNLLPQTFHIDMPEELVHELSKCRTDDEAREVGIEWATAQSRDLLKNEVPG
IHYYTLGRSDNIARIVKASF
>A0A1H7ST03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus maanshanensis|TrEMBL
MTQTPSIVDRIGSSGGRIPFSVEFSPPRDADAEARLWRAVREFEQMQPAFVSMTYGAGGS
TRDRTVRVTGALAEETTLLPVAHLTAVGHSVDELRAMVGAYADRGISNILVLRGDPPGDP
LGEWVRHPEGVEYAEELVRLVRDLGDFHVGVASFPEGHFRAPDLDHDTRYLVSKLRAGAE
YSITQMFFDVEDYLRLRDRVSRYDAEQGAKPIIPEIMPITSLRSVKRMVELSGSQLPREL
AERLDRAAGHGPEENRAAVREIGIELATEMSERLIAEGAPCLHFITLNFARATREVLARL
GLASSVR
>A0A1Z9BBM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium TMED100|TrEMBL
MELSIEFFPPKTEEGFSRLKKAAKKLSCLQIEYASVTYGAGGSTQEGTHSAVLMLSDIFK
KAVPHISCIGSNKSNIENILNKYKKTGFDHLIVLRGDLPSGFGKGGEFSNAIDLVEFIRK
NFGEGFRIEVAAYPEIHPQASSPEKDIKYFSEKIKAGANGAITQYFFNSDAYFKFVDDVH
KLGVDVPIVPGIMPITNFTQLARFSDNCGAEIPRWIRQRLSAFGDDSESIYLFGIDVISD
LCDQLISGGVPGLHFYSMNRADAILKINENIGTFT
>A0A395LAP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. M14|TrEMBL
MSPDYNPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPHDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNVMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNTKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLNEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRQPWKRETLPTDALVASRMEHIREGKEENQQEMAEAAAH
HPH
>A0A552ZFE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium sp. 018/SC-01/001|TrEMBL
MRPMADCPKNMHYGPCGGVRPDGQCEMRAGACAFPDVVPWDGASAQPRPVVAPLVLTDFS
CLPFDRADLSATAAALAGSCDAVLVGEHQNRPDFPPTVMAPLLLDAGVSPWITLSCRDRN
RVVLEQELRGLSLLGVQTVLCVTGDGRAYDVRPDVTQTFDLDGPRLVALAASLGVTAAVP
ETPTAPPVSGRPARLVAKQRAGAALAVLNHMTTPDVVASFMAAARSAGLTIPVLGAVAVI
TDDVSAAVLQGLPGLAVDPAVVATILHAPDPVQAGIEAAVTEARALLAIDGVEGVNISGL
ASAAGTRAGAEIKAEVGRRVREEVDHGR
>A0A5D2T794|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium mustelinum|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFDRMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFIKFVNDCRQMGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQFPHGRWGDSRNPS
YSALTDHQFMRRRARDKKLQEEWATPLKSIDDIQEKFKSFCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSLSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGTTDVNAVTWGVFPAKEIIQPTVVDPASFMVWKD
EAFEIWSRAWAALYPEGDLSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>A0A1H0YXC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. UC 17F4|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHIEIAAYPEMHPQARNFEDDLKNFVRKANAGADSAITQYFFNADSYFY
FVERVQQLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EDVITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A1I5C752|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus ornithinivorans|TrEMBL
MKITEHLKNAKSTLFSFEILPPLKGQSLKELLEGIAPLMDFKPPFVDVTYHREEFIYKKH
PNGLLEKISTKKRPGTVGICAAIMNRFQVDAVPHLLCGGFTREETENALIDLNFIGVENV
LALRGDAPKTEGRFVPENDGHHFASELVDQIIRMNHGKYLHEETETSFHTDFCVGVAGYP
EKHFEAPSMKFDLKYLKEKVEKGAEYIVTQMFFDNEKYFKFVEDVRAAGITVPIIPGIKP
ITTIGQITMLPRTFFLDLPDALMDELEKCKTNGEVKEVGIEWAIQQCKELVAADAPSLHF
YTMSKADATYKIAKEVF
>A0A7G5M0D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mumia sp. ZJ1417|TrEMBL
MPTARRLSEDIAAPTASFSFEFFPPKSDAGERTLWTAIRELEPLRPTFVSVTYGAGGTTR
DRTVRITERIATETTLRPVGHLTCVGQSRDDLRTVLGQYAAAGVRNILALRGDPVGGPGA
PWTSHPDGLDHGDQLVSLVSGLGTFCVGAAAYPKGHREAPGLDADAEVVVSKARAGAEFA
VTDFFFLADDYLGLVERVRARGCDIPIVPGIMPVTNLAQITRMAELSGHPVPASVVSRLE
PWVDDPDGLRAEGTLIATELCNTLLEQGAPGLHFYTLNRSRATRQIYQNLAHAAVV
>A0A8C6V3S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neogobius melanostomus|TrEMBL
MVNQVQRGDGTLSSRSDSSAASASGGDSSKESSRCSTPVLDADRTDRLRYKMRRRMESGD
HWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPSGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQSKDNISRHLSKAKHLGLKNIMALRGDPVGSDWEEEEEGFNYAVD
LVKHIRSEFDDYFDICVAGYPTGHPEAHSYKEDLIYLKEKVAAGADFVITQLFFRAIGIT
CPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIHQALEMCRVL
LDSGRVPGLHFYTLNREVATMEVLRQLGMWQEDPRRPMPWAVSAHPKRKVEDVRPIFWGS
RPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLVFEVFTCYIAA
QPNRKGHKVMCLPWNDEPLAPETNMLKDELEKVNTRGVLTINSQPNINGKPSTDPIVGWG
PPGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTW
GIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNL
VDNDFPLDSCLWQVIEDMFELLVTQN
>A0A0D0TT78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus gattii VGII Ram5|TrEMBL
MKITEKLQKAEKEGRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALKEAKSHGCQNILALRGDPVAGTST
WEPTPGGFMNAVDLVRYIHKHYPGDFCVAVAGFPQGHPETPDTPEGRAQEMEWLKAKVDA
GAEFIFTQMFYDTSIFFDWVKRVREAGINVPIVPGIMPIQNWEKFEKWVQRENIIVPSHF
YEALNPVRGDDEKVRQVGTKLVADMCKTILQHKEAGIKGLHIYTLNLEKGARMLLKELGF
EGRREQIAPLPWRPSLTPSRREETIRPIFWANRTRSYLSRTADWDEFPNGRWGDSRSPAY
GDLDGYPVSIGITAPDAYNLWGHPTTSFDLHTLFARFCRGDLAKLPWSTQPPASETSLII
EQLAKMNELGYLTINSQPAVDGVRSDDKVHGWGPAGGYVYQKAYLEFFVSPDLLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWAHLYPAGSPSRKLITDTMNTSYLVNIVANDFRDGMSIFEPFLLNQTTVGKVVEGV
KGTVEGIVEGVKGVVSA
>A0A2U1WV05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. TSO22-1|TrEMBL
MTSSAPAVSFEFFPPKTEKMEQSLWQAIQRLAPLAPAFVSVTYGAGGSTRERTHNTVTRI
QKETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPEAAGGLGGRYEPYPG
GYAYAADLVAGMRTVADFEISVAAYPETHPEAPNAQFDLDNLKRKVDAGATRAITQFFFD
NEKYFRFRDRCAAAGIHVPIVPGILPITNYARAVEFAGKCNATIPARMAETFEGLDDDPE
TRQLVAATVAAEQCQDLQAQGVEHFHFYTLNRADLTVAICRMLGIKAKAAVPAAG
>A0A519Y8F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKITEHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFDPPFIDVTSLREDYIYKE
QDNGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADSAFIPTKGGHCYATDLIEHIKNHNDGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNTDFRFLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLSQLNVLPKIFHIDLPEDLTDALSHAKSNAEAKEIGTEAMIKQCKELMDFGVPVLHF
YTMGKPEQTKRIAKAIF
>A0A0E3Y9W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blochmannia endosymbiont of Camponotus (Colobopsis) obliquus|TrEMBL
MVFYAIQWEKLNRYLVELYGNINVSFEFFPPYNYEMETFFWKAINSLGKLNPVFVSVTYG
ANTGTRDRTYNIIQDIKHRTGLIAAPHLTCIDATQQQLKNIAQKYWNSGIRHIIALRGDR
DRSVNYKHSTMMHAVDLVTLLKKIGDFDISVAAYPEVHPEAKNARDDLINLKRKIDAGAS
RAITQFFFDIENYLRFRDLCVSIGINVKIIPGILPIFNFQQLRRFSNMTQVKIPNWIVSM
FEGLSNSDIDTCKMIGVAIAIDMVKVLFKEGVRDFHFYTLNRSDLTYTICHVLGIRPKL
>A0A0D6EUS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methylopumilus planktonicus|TrEMBL
MPKKISYSFEFFPPSSPEGIKNSKDTRQQLSAFKPEFYSVTFGAGGSTRDLTLETVLEIK
QEGFNAVPHISGISSTKAEIKTLLDLYQQHNIKHLVVLRGDVPHGAVSRGEFKHANELVS
FIRQETNDYFHIEVGAYPEYHPEAVSSQTDIQNFKNKVDAGANSAITQFFFNADAYFRFM
DECLIADINIPIVPGVMPIYNIKQLARFASNCGAEIPRWLRIKLESYGDDLLSLRSYGVD
VVSELCETLIEWDVPSLHFYTLNQAGIITRIIQNIEGT
>A0A2N5X920|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudohalioglobus lutimaris|TrEMBL
MAKPHISFEYFPPKTAAGKEKLLNETTPALNALGPEFFSVTYGAGGTTRDTTLGIVSAIR
DAGIDVAPHLSFGGDDENTVAELLETYKSRGINRLVGLRGDMPSGMGAAMQLVHANDLVR
FIRERTGDHFHIAVAAYPEIHPESRSYASDIEFLKKKMDAGANSAITQYFYNVEAYFYYL
DQCQAAGIDQPIYAGIMPITNYENLARFSRNCGAEIPRWICKRMESYGDDQESVRQFGLE
VVTQLCQTLIDSGCPGIHFYTMNQVEPTRTIYNNLGL
>A0A4Y9F918|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus tengchongensis|TrEMBL
MKIRDLLKARKGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRERS
VLWAKRILGLKLNALAHLTVAGQSRKEVAEVLGRFVEVGVENILALRGDPPQGERVFRPH
PEGFRYASELVAHIRARYGEGLSVGGAAYPEGHPESTSLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIEIPILPGIMPITSYTQLRRFTEVCGASIPGPLLSRLEKHQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGFRPWARTSEGV
>A0A0Q8X3H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp. Root83|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGATRQDLRDILQVYKSEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQASNPSADLDHFVAKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVNVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHSEAPLAVWKELSV
>A0A1T5KHR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium WCE2004|TrEMBL
MKPFPSLEIIPPLKGITKTELLDSIRPLMEFSPRFINVTCHRDEYEFRQEPDGGYTRHLL
RKRISQTAVCAAVQAAFPDVEVVPHLICGGATADQIESQLQDFKFMGIRNILVLRGDALP
GEKRFAPEPGGYGHADELVAAIRRFEAAQGGGRIFTLGVGGYPEKHFESPNLETDIKYLK
QKVDAGADQIITQMFFDNAVFYDFVKRCREAGITVPIVPGIKPLSSARQVDLLPESFSID
IPVELTAEVAAHPKDAYSIGEAWCKAQCRDLLAHGVEEIHFYTMGRSENIINVLKDCF
>B9BC62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia multivorans CGD1|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLDAAPHLSCIGSSRDSLRAILDQYRSCGIRHIVALRGDLPSGMGSVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATKAICERLDV
>A5UUW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseiflexus sp. (strain RS-1)|TrEMBL
MKSFSEFQRRLQAGHIVVTGEIAPPRGASRATVERLALGLRDAVDAINLTDNQRGLGRMS
ALGAGIIIRQLGLEPIVQMTCQHRNRIALQADVLSGAACGITNFLAMTGDHPKIGDHPDA
KNVLDLNSFQLLKMLRTMRDEGKFQSGVALTEAPRFFLGGVANPNIERVARLERKIQFGA
EFIQTQILFDLDRFRQWMADARAAGLHQKAYILAGIMVVKSAQSARFLRDHLPGSRVPEW
VIERMERAAHPEEEGIAIAAELAQELLAIEGVRGVHIMSVGWTKAIPQVVARAGLIPRPP
APPADDVQE
>A0A4P6Y4G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae complex sp|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7U8P6U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella suis bv. 4 str. 40|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATCEDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMVGIRPKTQAAL
EVA
>R4LZH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes sp. N902-109|TrEMBL
MLDRIGASHGGFSVEFFPPRDAAGEQRLRAAIRQVEALDPAFVSVTYGAGGSSRDRTVAT
SGWVTEQTSLRAVGHLAAVGHSVTELRAVVGQYAAAGVHDILAVRGDPPGDPLGPWEPHP
RGVTYAHELVALIRSIGAFSVGVAAFPYGHPRSADLAEDIRHLRQKVAAGADYAIAQLFF
SAADYLRLRDRMAAQGCAVPLLPGIMPLTTPKVLAKAIELSGVRAVPPIATELLRHAADP
ADFRAAGIDATTRLCAELLAEGVPLLHFYSLNFTTALLEVLNRLTPAHRRG
>A0A845T8B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus sp. G4468|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTQEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHAIIKDIKERTGLEAAPHLTCIDACREELQHIAQDYWQSGIRHIVALRGD
LPDNSQKPDMYAVDLVRLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKKKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMFD
GLDNDPETRALVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPQLAKV
>A0A809S746|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfobacillus denitrificans|TrEMBL
MTKPEISFEFFPPQTAEGAEKLRATRRQLAQLKPAFFSCTFGAGGSTRDRTLETVLEIQA
EGLPAAPHLSCIGSTRDNVRAILGRYRQAGIRRLVALRGDLPSGMADPGEFRHANELVEF
IRAETGDAFRIEVAAYPEYHPQAKSPREDLLNFKRKVAAGANAAITQYFYNADAYAHFVE
EARALGVAVPIVPGVMPIANFSKIARFSDACGAEIPRWMRKKFESLGDDAAAVRAFGLDV
VTELCERLLAQGAPGLHFYTLNQAGLTTTICQRLGL
>A0A7V3RNJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmataceae bacterium|TrEMBL
MRFAEFYNGSTGPHISFEVFPPQTDAAMESLRRVLPELIALGPSYMTVTYGALGSTRERT
LEIAALIKHEYHMESACHLTCVGSSRADLDGILDAIRRSGIENIVALRGDPPRGETAFVP
PPDGYSHGNELVAHIRRRYGAAFGIAVAGYPEKHLESPDRESDLRYFKNKIDAGADIAIT
QLFYDNADFFSFVEAARALGVTKPIIPGLLPILSAKQVRRITSLCGSKIPPTLQAELEAA
GDDDSRAEEVGIRQCVAQAAELLRHGVPGIHFYVLNKSSHMRRILAQLRPVLAEIRQN
>A0A1S5WDD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gallolyticus subsp. gallolyticus DSM 16831|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLETGADIIQT
NTYAAKRHRLKGYAYDDQVKKINQAGVKIAREAAGDDAFVLGTVGALRGLKQCDLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEAELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKETNFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDELADLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEVVKDDKETCQKLALEESKQLIDRALEHFNGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A2D3U6P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces peucetius subsp. caesius ATCC 27952|TrEMBL
MALGTASTRTDRARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVAPNFVSV
TYGAGGSTRAGTVKATQQIAADTTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVKHPEGVQYAADLVRLIKESGDFCVGVAAFPEMHPRSSGWDEDIRHFVD
KCRAGADYAITQMFFRPEDYLRLRDRVGAAGCETPIIPEIMPVTSVKQIERFATLSNAHF
PAELKMRILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHEQS
>A0A7J9ZV03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangiales bacterium|TrEMBL
MLRESLSAGRFVVTAELTPGRDPSPGALSRRAAALAPYADAVNLPDNPGARVSIASWAGS
LIALWADAEPVMQLTGRDRNRIALQSDLVSASAMGVRNVLLLTGDPPGAGDDPDAAPVFD
LDGPALIRAAAGLRDRGRLLSGREVSPAPDLFIGAAEDPFAGPPEVRAERLAVKAEAGAD
FVQTQFVFDVRAFEAWMSAVRARGLHERCAVLAGVGPLGSPRALRFLAEELPGVRIPDAV
VRRLGSVPEHRFAEEARRLAAETIAALRATPGVAGVHLMTMGRESEIPELLERAGLTPEV
NRRAG
>A0A7W4I7E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconacetobacter diazotrophicus|TrEMBL
MSFEFFPPRTDRMAETLRQTVASLVPLAPRFMSVTYGAGGSTRDRTLDIVASLVRETTVP
VAGHLTCVDASRDQVDAVARAYWDAGVRHIVALRGDPAEAGAAYVPHPDGYANAAALVAG
LHRIAPFEISVAAYPETHPAAVSAAADLDNLKAKIDAGATRAITQFFFESETFLRFRDHA
ASAGITAEIVPGILPVGNIAQAYRFADMCGARVPDWMRRLFDGLDDQPGARAIVTTTVAT
ELCRRLREEGVDHFHIYTLNRADASLALCRLLGR
>A0A543K7P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ornithinimicrobium humiphilum|TrEMBL
MTTPQPRTAETRISVELVPRSAESLTAEMAEIAQRLPGVTTINVPDLLKFPLRSWDACGV
VRGAPARADGTAYPVIPHVRAADVDPDAPLPMAEAIRAHGITEVLVVSGDDADYFTHHTY
PVDAVDVIRRFRAELPEVRVYAGLDPYRSGIATEMRYLERKLSAGAVGVFTQPFFDTSYM
ATWGRVLPSDIEVWWGATTVTTQASIGYWRRRNLVAFPRDFEPTLAWQRDYARRAIDAAG
EQGQNIYLMPVRTSVLDYLEGVI
>A0A1S6QHI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus curieae|TrEMBL
MNLTELSKTKTIFSLEVFPPKKTSPNSTVLDTISKFKAVNPDFISVTLGAGGSNHFEGTI
EVADIIQNQLGIEAVAHVPGLYQSKQDVLKLLDKLNSINVENVLALRGDHIPERKPVGDF
NHANELVEFIKENRPEFDVTGACYPNCHQDSKDFIDDIANLKRKVECGADHLITQLFFDN
NAFYDFYEKTRIAGINVPIEAGIMPCTNKNQIDRITAITGVPVPRKFRAILDRYADNKEA
MRDAGIAFAVDQIIDLVSQGVDGIHLYTMNRADIACRIYEDTKSVFKAAEVK
>A0A1Q4BG60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 62-17|TrEMBL
MSLDVVRPSRQSNRPLRVSFEFFPPKTAEMETSLWHAIERLAPIGPSFVSVTYGAGGSTR
ERTHSTVSRIIRETNLKPAAHLTCVAATKDEVDDVVRAYWDVGVRHVVALRGDPVGGIGT
TYAAHPGGYENSTALVAGLKRLGDFEISVSAYPEKHPESATLDDDIDVLKAKIDAGATRA
ITQFFFENDHYLRYVDRVRAAGIHIPIVPGIVPVENFRQTASFAKRTGAYVPQWLADRFD
GLDDDATTRRLVAAAVAAEQVFDLLDRGVQDFHFYTMNKSELVFAICHLLGLKPQPAREA
A
>A0A4P7RLM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. PAMC28705|TrEMBL
MTSDAVRGRSSEGWVTRTPSIVDRLRTSTESKIPFSVEFSPPRDEAAEARLWRAVREFEQ
MQPAFVSMTYGAGGSTRDRTVRVTGDISENTTLLPVAHLTAVSHSIDELRSMVGAYADRG
ISNILVLRGDPPGDPLGDWTKHPEGVEYAEELVSLVRELGDFHVGVASFPEGHYRAVDLE
QDTRVLVNKLRAGAEYSITQMFFDVEDYLRLRDRVAAFDPEQACKPIIPEIMPITSLRTV
RRALSLSGSALPSEIDERFTRAAGTGAEEDRAAVREVGIELATSTCERLIAEGAPALHFI
TLNFARATREVLTNLGMCAARV
>J7VDJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia Ab55555|TrEMBL
MSAPTSLRVQAFLDAFSLEVSARAMPALGAEATRIPRGTTISIPWLASEDDDARLAAARR
VRELGFEPMPHLSARRIGSRAVLERFLQRAANEAGVAQCLVIAGDLATPAGPFADSASII
ESGLLERAGIKVVAIGGHPDGHPVLGSDACWQVLEHKCQSIEARGMAPMIITQFAFDADI
VLAWLHALRARGIHVPVLVGVPGPASISRLVRYAAMCGVGASALMLSRYGISIGRLLGSA
GPEVFVDRLAGGLTDAHGLVSPHFFPFGGIAQSLDWIKQHRALPSVARR
>A0A3Q8ZEM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7D.F.Ca.US.005.01.1.1|TrEMBL
MIGRQRDENPAGIDLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIASGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A2L0LXD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. PONIH3|TrEMBL
MSLLKTTLDANAFACILEFVPKPSAERFATLDTLMARTQLCGWPLTVAIGDRVGSALDMS
PLDAFNSLAEPVPALLHFSGKDRERHELLAQLQCMDAAGLDQLLLLTGDRLPGHVPGERP
VRYLESVAALQIVRQARPHWLLAAALNPFKYQEAEGGAQYSKAEKKLTAGADLFILQLGF
DIDKHQEAFDWMQRQPRPKPLMACIMALTEGRAGMLGHVAGVTVTPSMRALLAAEAAVSK
TYAKERANQRLALQVIGLKLMGYAGVHLSGIHEVAQFEALEQTIEVLQPQFSSLRDWAPA
WEAAWQAPGLTPVTFHPPGHAWRLGQRQITASNKEKVRYHLLSAMHHQLFSRTTALSKAF
GWAVTRPLWANPTAAQWLHQLERRIKRPMVGCDTCGSCRLEDTLYICPETCPKGLANGPC
GGTSLDRCEFGDRECVHSAKYRLAVSVGRTEVLRERLIPCVQVENRQRSSWPGWFEGGTS
RSPSLQPDVAPEFNE
>A0A7S8EAA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phototrophicus methaneseepsis|TrEMBL
MSQQIATKLAFIDRLQQPKPLLVDGAMGTMLQQRGNLKISACFDELNLTQPELVQGVHMD
YLAAGADIIETNTFSANRVKLAEHSLADRVGDINQAAVAIARRALQAAGRENDAYIAGSI
GPLGAGIAPYGSLTEPEARKAFNEQLQALVDAGVDLLLFETFANDDELLLAVEEAQTIAP
EMPIVAHATFTPDSRTYLGRTPARVANALYKAGATVIGVNCGGGPAHISEMLQAMHNAVP
KARLSAMPNAGYPQAMGGRVMYPAQAEYFGDAALTLRAQGAVIVGGCCGTTPAHISAMRT
ALDDASRVALVGHVDVHDDEESSTEQLRPTEFAERLQDGRFTVTVEIAPPRSYTAEKLLT
NARLLRDAGADMLNVADTPAARMRMSAWAVAHLLQQKLGIETVLHFPTRGRNALRVQGDL
LAAHALGLRNLFITMGDPARIGDYPDATDSYDIAPSRLIGVVKQEMNEGRDMGGSSIGRP
TQFTVGCALNMAADDLDREMRVLEKKLSSGADYALGQAVFDPPRIDRFLEAYEKTFKEAF
KLPVLMGVMPLYSLKHAHFLNNEVPGIEIPEAIFKRLEDAGDGAAEEGVAIAVELMEQMR
DRVQGAYIIPAYGRYKLAAEVVAAVSG
>A0A836RU53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MKVTRHLAQANEPLISFEIIPPKRGGDIKSLLQVVDHIAQYNPPFIDITSHAAEVIYEET
PQGIQRKVKRKRPGTLGICALIQNKYDIDAVPHVLCQGFTREETEDFLIDLQYLQIENVL
AIRGDESNYKKPLLHGRSANVYANDLVEQIANMNKGKYLEDSLVDARPSDFCIGVGAYPE
KHFEAPNLETDIQYLKKKVEAGAEYIVTQMFFDNRVYFNFVDQCRQAGIRVPIIPGLKII
TSKNQLTNIPRNFFVNIPVELTNSFMEVSREDVLKTGVEWTYRQVKELLDKKVPAIHFYI
MQDSKPIRMLMERLGK
>A0A849ET09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatitalea sp|TrEMBL
MKLKDALGKKKFVVTSEVQTPLGDDSPEQLVDRLKRIRGRVDGVSVTDVDLEGVVGDSIH
TCELLEKSRFNAIYQTTTRDKNRIQLQKDLAQAHQVGIENLLVFTEDYRITGDSIQEQMF
FHVDSGKLGSVLQHVREGRTIEGEELPEPFDFTLGSGVESLWGKNIPKQGMQGMEALKLM
GAGFFLTTPIFDLEQFDKFMRQIRMLDVPVIAEVLLLRNAAMARFINRHFKPGLVPEWVI
QKLDKATDKRQASIELFGDLAKGLKEVCNGLHIITLGGEDKLQPYLDAANLR
>A0A498GXB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. MSH10X1|TrEMBL
MLFNFREKLNSSKFLVTAEVSPPKGTRFSAPLEDARQLKGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDFPSCGDHPGSKP
VYDLDSVQFLQLVRKLDSGIDFAGNRLDGGTSFCAGAVSGIDPEKTIQLIKLEKKVRCGA
DFIQTQAVYDVGMFEEFMEATSHLEVPVIAGLIPLKSLGMAEFMNKNISGINVPEEIMLR
IKDAPDPVEEGLSIASETIKELIKLSRGVHIMPVGSHKNTPKLLSLAGLSGK
>A0A852AW69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloropsis cyanopogon|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSRDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITRHLQKAKRLGLKNIMALRGDPAGAEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEADSYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A1S9A977|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. KIM|TrEMBL
METPNFSIEFFPPKTPEGAEKLRATRQKLAELQPKYFSVTFGAGGSTQAGTLQTVLEIKG
EGHEAAPHLSCIGGDRASIGAILKQFQEHGIRRLVALRGDLPSGYGGAGEFRYANELVEF
IRQETGDWFHIEVAAYPEMHPQARSPQDDLQNFARKVKAGANAAITQYFYNADAYFTFVD
NARKLGVDVPIVPGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTALAERLLAGGAPGLHFYSMNQALATTAIWQRLVK
>A0A4V1LC55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter defluvii|TrEMBL
MFETLIQKLQEDRFLTLETTPQHEPSMHNIIERIKKFKLQDRVDGFSCTDNPLAKLKYNA
LFASLKLQTEFNKPVIATMSMRDRNKIALQSDLMGANDFDVRAILALTGDPAKMSDQPHA
KGVFEANSLMLLKIIKSFNYGMDMSGHPFKIEPKQIFPFAVTNSYAKNFSTLEKKMNLKI
QNGAVGIISQPVFDIENAKKLLESFNIAKEGVEGDKKKAQLIFGVFPVTKLRTALFLSAQ
VPGIHVPQFWIDALETAHNISEEEEYKVGMQLSQDLFRDLNKLHPKIHLMTANRFDVANE
IIS
>A0A2D9CQD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp|TrEMBL
MTTPAISFEFFPPKTLEASXRLWDTVQTLAPLEPRFVSVTXGAGGTTRQLTREAVETLHK
SAGLXVAAHLTCVDASRXETLAIADDFARAGVTXIVALRGDPPKGSGGXRPHPDGFEDSC
ALISALADTGRFNIRVGAYPERHPEAADDAADVDWLKRKIDAGASEAITQFFFEAXTFLR
FRDRXAKAGIDAPIVPGILPIXNWSNTRRFATACGTGVPQWLDXAFDKXTRDGREDLLAT
ALATELCSDLLEEGVETLHFYTLNRPELTRDICHALGVTPKVKLRDVA
>A0A0M1K7Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae|TrEMBL
MISIDLPSHTRAITDAYSLEVSVKDIGALTKAAPRLPPGSSMFIPYLPGQHDAARLAAAQ
LVRSLGFEPMPHLSARRIGAPEELQAFVARLVDEAGVTRCFVIAGDPSTPKGPFADSLSL
IETGVFERSGIRTIGVAGHPQGHPIMRTAEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
MVVTWVEALRARGITHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLASRLTDAHGDIRLHVFPFGGIAQSVEWVAQYRSRAWS
>A0A1E7H8W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium S3730MH12|TrEMBL
MAVSSECGPPRSSDPAHIIEKGHLIKNHVDCINITDNQTSVTRLCSLAACIHLKQEGLEP
VLQMVVRDRNRIALQSDILGAASHGIHSMLCLSGDHQRFGDSPEGQNVFDIDSMQLLQTV
RYMRDEGKFLGGDAIKVPPNMFVGAAANPFADPFEIRVPRLAKKIAAGAEFIQTQCVYNL
DKFELWMKGVVERGLHEKVFIMPGITPMRSVGMAKYMARAVPGMDVPKELIDRLSGVPKD
KQSEEGITIAVEAMERLKECTGVAGFHIMAIEWEEKVPEMVERAGFYPRPEFD
>A0A1D2TST8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium sp. SCN 69-14|TrEMBL
MSPHETALGPVARAAAGNARRPSVSFEFSPPKTPEAEESLWEAIRRLEPLNPAFVSVTYG
AGGSTRDRTHRTVVRMLKETTLKPAAHLTCVEASRAEVDEVVQAYWDAGIRHIVALRGDP
PGNIGGAYAPRSDGYLNATELTAGIRAVAPFEVSVGLYPQIHPESPSLDHDIDVLKAKVD
AGATRAITQFFYDIDAFLFFMDRLRKAGVNIPVSPGIMPVSNYKGLKKMAGPVGIPLPAW
LGNLFDGLDRDAETRKLIAASVASEMCVRLVEEGYSDLHFYTLNRADLVYAICRVLGVRE
TPSEIAA
>A0A7X0DV01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MIAPQSESREKAPLADLLSHYSIEVTSRDLPSLQSMTATLPPGSEVFVAHLPKEDIGLLV
RAAAGLRDAGFVPVPHIVARNIRNRPELDTMLARLSEEAGVRHALVLGGDRDDAAGAFGS
ALDLIETGLFQTYGIGRIAIACYPEGHPRIAGAVLDSALTAKVDAAARAGLDLLLVSQFL
FDRKPLLSFARRLRERGVTVPLRVGIAGPASRTKLLKYALRCGVGASLRALRERSEIARN
VLSGETPEELLIDIAAAQAAEPHLGISGVHFFTFGDPAQSIRWAKQQQPSD
>A0A0M9AF59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus aquaticus|TrEMBL
MKIRDLLRAKGPHFSFEFFPPKTKEGEEALFRTMAELKAFRPAFVSITYGAMGSTRDRSV
AWAARIGELGLTPLAHLTVAGQSRKEVASVLERLWQVGVENILALRGDPPAGERVFRPHP
EGFRYASELVAFIRERYGEALSVGGAAYPEGHPESVSLEADLRHFKAKVEAGLDFAITQL
FFNNAHYFGFLERARRMGVEIPILPGIMPITNYQQLRRFTEVCGASIPGPLLSRLERHQD
DPGAILEIGVEHATRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGFRPEPLPPRSPGS
PPAP
>A0A154IHG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MAMSQAIHLRDQSDVLDDFSVEVTTKDTAQLAAMSGAIPKGTIISIPFLSTESDADRIRA
AKMVRQAGYVPLPHIAARRLGSESMLSAMLSALVNDAQVSRLLLVAGDADPPKGPFLDTA
TILRSGILEQHGISNVSIAGHPEGHPVQNAAMLTSALLEKRLIMEAANIEWSIFTQFAFA
SEPVLAWIGELRRLGIEVPIHIGIPGPASVRTLLKFAAVCGVSASTSVLKKYGLSITQLL
SSAGPDALVNEYATGLSNAEYGDVRLHFYPFGGLHKTVDWLQEYRTRHS
>A0A1H9PIT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium cyclohexanicum|TrEMBL
MDARHRDDHRREENFAGLLMRVTRPTFSVEFFPPRDDAGAVVLHRAIRELEPLHPDFVSV
TYGANGSSRERTLGAVRDIVESTGLRVVGHLTCTAQSVTQLEEVIDTYGELGVRHILALR
GDMPGGPLACWQPHPHGLRNATELVELVKSRGDFCVGVAAFPDIHPGSTPGDDVAALCAK
QAAGAEFAITQLFFRPGSYRELVSRMRAAGCTLPVLAGVMPVTTIRQLDKFAELSGAPLP
EHLRTRLGAVASDPERVRQVGSQICAELATELLGDGVPGLHFFTQNRSVATREILARLLA
SRH
>A0A543HXR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klugiella xanthotipulae|TrEMBL
MSAAARGGFVPFSFEVFPARSARAALSLGHTVQNLAAAGPDFISVTYGASGSSRDSSLDL
LRYIREHTTAKPLAHLTSIGSTRAEIEQLVAEFCAAGVYDFLALRGDPPAGVPEEEVELG
ELGDTAELVRLIRATVARRVAEHAPDVGLAGAGPAAGRVCIAAFPNGHIRSETKHQDVLA
LLAKQEAGAEFAITQLFFYADDYLDYVAAAREAGVSIPILPGLMPVSTEAQLRKVSELAG
QVAPADLLADFQAADGFAPEYGVAHTTRLATELIESGAPGIHLYTFNRHQSALSVLRELG
VITTHPFDKEIA
>A0A4U6CBF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquamicrobium sp. LC103|TrEMBL
MADPRLSRRSDLGDRIKVSFEFFPPKSDEMEGRLWDTVTKLEPLSPHYVSVTYGAGGSTR
ERTARTISRILTESSLRPAAHMTCVDATRGDVDEVIRQFADMGVTRFVALRGDPAAGVGA
KYRPHPDGYSNGADLVGAIRRAGDFEVSVSAYPEKHPESADFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYVPIVPGVLPIHNFKQVANFSSRCGAHIPAWIAERFD
GLDKDPQTHALVAAAIAAEQVHDLIERGLGEFHFYTMNRADLAYAICHMIGARPEIAVAA
TSAAA
>A0A369L5Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Senegalimassilia anaerobia|TrEMBL
MDTVENIFAQARQMGAQPVSFEIFPPKGELSMESARTIAQELAKLDPAFISVTYSAGGSG
NKQATAEIAAMIQDDHDVPAVAHLTCAGASQQSISTAVADMKDRGIRNVLALRGDLPEGY
EPGDFLYAKDLIPVLADAGFCVGAAAYPEGHIDCDSLRLNVEHLRQKQDAGASFLVTQLF
FDNDCFYRFREGAEAAGITVPITAGIMPFMSKAQIQRMVFMCGASLPSPIIKLLARYEDD
PASLRQAGIEYACRQLTDLQAHGVDGLHVYTMNNPEIARAASCALKVALVS
>A0A4R2SMM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PP-CC-2G-626|TrEMBL
MSTRTLYPAERGDLRLSFEYFPPKSEEMDTQLTRTAAILNAYAPEFVSVTYGAGGSTKAR
SLTTVRRLIDDCSIPGTAAHLTCVGATRAEVDAVVEEFAAAGVRHFVALRGDPQGGIGAQ
YQPFPDGYENAAALVAALSRSGRFQISVSAYPEKHPESSDVDADIDMLKRKVDNGATRAL
TQFFFDNNDFERYLERVRKAGISIPVVPGILPINQFGQVSKFAGLCGARIPEALSARLAH
LDESPEERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFKRTDEAVVE
GAAA
>A0A419AYG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium carotovorum|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLRDIAQDYWQSGIRHIVALRGD
LSPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTTMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A091ERD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corvus brachyrhynchos|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLRDKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A154R4I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. FW510-R10|TrEMBL
MPSISFEFFPPKTEEQRTQLDRAAQVLKAHQPEYASVTFGAGGSTLSYTGDTVARLYHEH
GLEVAPHLSCMGGTRAEIGALLDSYRAAGYRRLVALRGDMPSGMASAGDFRYAAELVGFI
REHCGNHFHIEVAAYPETHPQADDALRDLQHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VHRLGVSVPIVPGIMPIANYSQLKRFSDLCGAEIPRWIAKRMQAHGDDAESVRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRARATQAVLQQLS
>A0A3S8XVS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. KPB2|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPTADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>K9P9B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium gracile (strain ATCC 27147 / PCC 6307)|TrEMBL
MMPLSWRWPLQLRQALADGRFAVTAEVTPPRGGDAGRTLEAATALRGLVHAVNVTDGSRA
VMRMSSLAVCRLLLEAGIEPVLQMTCRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAG
DQPAVRAVNELEAVRLLQLVRGLNAGEDPVKGELPDGATALFPGAAADPQSPSWSGLLSR
VRRKQEAGARFLQTQMVMDAAALRRFVEEITGPLGLPVLAGVFLLKSARNAQFINRVVPG
ACIPQSLIDRLAGAADPAAEGVAIAAEQVATYRSIAQGVHLMAIKAEHRIPQILRLAGLV
GAAGGEVGAQQLGHGLLLR
>A0A1G5KGN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkaliphilus peptidifermentans DSM 18978|TrEMBL
MLIKDIFKEKTVISLEIFPPKPTSPLDTITNMLEEIKDLTPDFISITYGAGGSTKRHTVD
IASMVKNKYKIEALAHLTCINSTKDEINRIFQLLKENNIENILALRGDHPDNQPINIEEN
QDFNYAKDLASYAKSYGGFSLGGACYPEGHLECKNTVENLHHLKEKVDNGLDFLITQLFF
DNNLFYNFKEKMELLNIKVPVSAGIMPVINKKQVEKIISLTGASISPKFLKILDKYGDNP
SALKEAGIAYATEQIIDLMANEVDGIHLYAMNRPEIAKSIFSSIGSIRKYAANS
>A0A855IMQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio lentus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASRKELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQIAAL
>A0A7C1E1M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
MALFTPGRRWQPPFLPFKREPFGRRLLARIERWTKGPLWGCRMCGNCLLQETAFICPMEC
PKGMRNGPCGGSTPERCYVDETRPCIWYRIYDRAFRMGREEKLLEVLPPLDWDKAGTETW
GDVFRSVRKYGTGKFLKSFFSRDREIKTGAWEGVFRPVRQPGWWQGDSAYHPPASLEPVS
RLERELRAGKFVITTEVSPPLSTTTGKLKRDIEMVRNLVTAVNFTDSASASPRMSSMACC
KVAAELGADPVLQIAARDKTRSGLQADVVGANVMGVKNVLCITGDHARIGPTPTSNMNIL
DMDAVQMLWILRRMRDEGVYLDGRKMKSPPVLFLGAAASPFASEPHFQALREQKKVNAGA
QFFQTNVIFDPQGLETWLEALYKRDVLNKVYILAGVIPIRSKRMAHYLHDTIPGVRVPEW
ILNRFEETREDDCEELGVEIALDLIEKIRTKQGIHGLHLMSVGWEAIVPRIIGEAGLTPS
P
>A0A7Y9WB54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia bryophila|TrEMBL
MRRSSPSSCPSRSGAGGSTQQGTLDTVVDIAKEGIEAAPHVSCIGSSKDSLRAILNEYRA
HGIRHIVALRGDLPSGMGEVGELRYASELVSFIRAEFGDWFWIEVAGYPEYHPQSRSPRH
DMDNFVRKVKAGANSVITQYFFNADAYFRFVDDAQKLGVDVPIVPGIMPITNYSQLMRFS
EMCGAEVPRWVARRLESFGDDRESIRAFGLDVVTDLCERLLDAKVPGLHFYTLNGAAATK
AICERLNT
>A0A851G8G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. SECR19-1250|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDAIGDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A847EJ85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidales bacterium|TrEMBL
PLKSVGMARYMNKSVAGVFVPEDLIQKLKNSEDKTAMGIQIAADLIKGLKDLCQGVHIMA
IGWEKKVPQIIEASGLNK
>A0A0H2XJ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus (strain USA300)|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLYGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A1Z9WH45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillales bacterium TMED59|TrEMBL
MSEQIQFAMQNWSIEFTPSNKTKIDDFRRVLPIGTTVNVTAIPGTDPALMMATVEQLATQ
EMNPVPHIAARGIASISVLENXLASYREVDVTEILLIAGGYQSPVGDFKSAIEVLETGLL
QXVGIRKIGVAGHPEGSPDIPEXELKKALKQKNXFAEETGIAMYLETQFCFDAQAILRWE
SEIRADGNXLPIRVGXAGPAQXKTLLHFALISGVXPSLQFLKKQALHVTKLLSVQDPYDL
IADLAPHVNEHSPTQLQSLHFYSFGDFSQTARFAHELAMSGTR
>A0A2E9M8L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidales bacterium|TrEMBL
MTFKDSLATKEFVITAHVNLAQASNAESLNRQGEILRSVVDAVQLTETTQVHMSGLAAAA
ILIQQGIDPIIHMNCRDRNRIALQRDFLGAAALGVTSALVMRGKKIPDSDKVGVRNVFDT
PALEFMAYIQSLKQSANASLISDFRVGASAEIFNPNEDWTPNNLIRKCDAGANFIQMQLC
FDMDVVRNYMRHMISSKLTHRANFIMALSPLPSADVARWMRDNIKGALMPELIIERMERA
ADPEREGIEICGELLTELTTIPGVSGVNMLTMGNLETIPAAIDSSGVRHSQ
>A0A5C7YJP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTEHIQNANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LANGLLQKKVVKKRPGTVGICAGIQNKYEVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGHAYASELVTQISNLNKGIYLDEDLQNSTKTDFCIGVAGY
PEKHMEAPSLDSDIHFVKQKIKNGADYIITQMFFDNKKFFDFVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMAVVKAKDNDAVKQIGIEWCVQQSKELVAAGIPVLH
YYSMGKAENVKAIAREIF
>A0A354DCF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTQHIENANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPSGLLQKKIVKKRPGTVGICAGIQNKYDVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKNEIYFRPEKEGNEYASELVTQIHNLNKGIYLDEDLQNSSCTNFCIGVAGY
PEKHMEAPSVDSDIHFLKQKIKNGADYIITQMFFDNKRFFDFVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNDAVKQIGIEWCTAQSKELVAAGIPVLH
YYSMGKAENIKAIAKEIF
>A0A2E4PEX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTEHIERANGKALFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEYKE
QPSGLLEKRVVKKRPGTVGICAAIQNRYKVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VLALRGDAVKSEIYFKPEKEGHQYATELVTQIDNLNKGIYLDDHLQNTSATNFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGATYIVTQMFFDNKKFFEFVAKCRKEGITVPIIPGLK
PISTKKQLNQIPHRFKVDLPDELIMEVVRAKDNDAVRQVGIEWCISQSKELIAEGIPVLH
YYSMGKSDNIRAVAKAVF
>A0A2E4PJP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTQHIEKANGKTLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPSGLLQKKIVKKRPGTVGICAGIQNKYEVDAIPHVLCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKNEIYFKPEKEGNAYASDLVKQISNLNKGVYLDEDLQNSSCTNFCIGVAGY
PEKHMEAPSMDSDLHFLKQKIKNGADYIITQMFFDNKKFFDFVEKCKKAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMEVVKAKDNDAVKQIGIEWCLQQSKELIQAGIPVLH
YYSMGKAENIKAIASEIF
>A0A060TB28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastobotrys adeninivorans|TrEMBL
MSKITEVISGLRPDEPYFSYEFFPPKTAAGTANLNARLERMSKLGPAFINVTWGAGGSTA
QKSLSLAATCQKDLGLTTCLHLTCTNMDQTILDAALKQAKQLGIRNILALRGDPPRGQEY
GWTGASGEFQYAVDLVKYIRKHHGDWFCIGVAAYPEGHIESSAEGPVQDPGKDMPFLLEK
VKAGADFIITQFFYDADAFVRFENMMREYDPCLADIILVPGLMPINTYQQFMRASKLCNA
AIPDQIRQQLNAIANDDEKVKSLGVRILCDLISTIRIKTKNRVRGFHFYTLNLEKSVALT
LEHSGLLQPTPSTEEEAIASSDEEDGIVADNMSRAARRKSSVVSNRAIVEHSNRRYSDAE
VSPEEAGHESRENPRKRALAISSGEGDLGREATWDDFPNGRFGNSRSPAYGQIDGYGPSL
HVEPSRALKIWGYPVEPKDITKLFVRHITNELDALPWSEEPLSGETALIQEQLLQLNEAS
LWTVASQPAGNSIKSEDKIFGWGPRGGKIFQKAFVEFFVSDEDWKKIKAKVEENEWVTYY
EGNSSSENGFSTNLEPGSSNAVTWAVFPNREIVQSTIIEEESFLAWRDEAFSVWKEWQKL
YHPGSATAKLLQHIYDTYHLVSITHHDYFHDQALWDMLQAIVS
>A0A1T1J094|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. MF4642|TrEMBL
MSKKVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A519NU52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKITEHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QDNGLLQKVAYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADSSFIPTKGGHCYATDLIQHIKNHNDGKFLHEDVDTFKSDFCIGVAGYP
EKHFEAPNLNADFKFLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPDDLVDGLSQAKSNTEAKEIGTAAMIKQCKELIDFGAPVLHF
YTMGKPAQTKEIARAIF
>A0A2Z4JPU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter paneuropaeus|TrEMBL
MELSVEFFPPKTPEGENKLRLVRERLSEVLKPAFYSVTFGAGGSTQSGTLKVVSEIHAAG
AMVAPHLSCVGSSRESVCQMLKQYQALGIKRIVALRGDLPSGMGQYGEFHHANELVEFIR
SETGDWFHIDVAAYPETHPQAKSPASDIDFFVQKMKAGANSAVTQYFYNTDAYFRFVDEA
YEMGVTQPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDVASIRAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLSLGS
>A0A1I7T4S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis tropicalis|TrEMBL
MTNAGEAQVVENHDTIKKIDSLSTMPYCGVDTDDNAAVEDRAVFETGKSWSPKHYELLHE
RIERLIDEKQAFFSLEFFPPRFVNGVPNFLERVERLSEGGSVFVDMTWHMGSDPANIDKV
TSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPGTEL
EDTHQFRALDMIRWIREEYGNYFSIGCAGYPLGHPQAPSYKADLMYLKAKCDAGANFVIT
QLFFEAETFEKFVRDCREIGITKPIIPGIMPIMGYESIKRIAKLSQLEIPQHILDDLEPI
KHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNREGSIREILKSLGLWKLEGDRVF
PWKNRSQHPIRCLESVRPIYWSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLS
NLTTLRNGDDRLAMFGKTIESFEDVKQVFINYITQSPNASGVKVTVLPWTEAETGVQPET
SLITEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSEK
LIQIIERDFPVRVNYHAIDRNSTFDKTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRA
WRDEAYQMWMAQWGDFYPKESKSYGVIKSIHDEFRLVTLVDNDFQKPSVLFDVLQKALEE
LRK
>R4YZP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Microthrix parvicella RN1|TrEMBL
MAPGTPHSSVPSRPDRSTSAHQDARIDDLLAEGPTLSLEFFPPKTDRGVANLLDTVDELE
DLNPDFVSVTYGAGGSTRDRTRDLVVSANADRNYPVMAHLTCVGHTRSELAELLEDYAAS
GVRNILALAGDPPADGSPAGGDFTYATELVELIREVGDFSVGVAAHPETHPRSPDRASDR
RHLADKLEVADFAITQFFFSASDYFEMVDELTALGVTTPIVPGVIPVTNPVSVARFADMA
KAHRPHELWARYESVADDEAALMEVAVEAAANLAEELLAGGAPGVHLYALNRAEAPLGVG
ARLGWRIRPAVEATDG
>A0A260S820|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 15-2388-1-1a|TrEMBL
MNSESHSNGRASPGPTCSEHLSSGRPDGLRWGATYDLRVSEDSVRGRSSRGFVTRTPSIV
DRLRTEPEARIPFSVEFSPPRDEAAEARLWRAVREFEQLQPAFVSMTYGAGGSTRDRTVR
VTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRGITNILVLRGDPPGDPLGDWEKH
PDGVEYAEELVRLVRDLGDFHVGVASFPEGHHRAADLEQDTRCLVGKLRAGAEYSITQMF
FDVDDYLRLRDRVCAFDAEQGAKPIIPEIMPITSLRSVRRMLELSGTTLPSHLDEKFTRA
AGSGPEEDRAAVREVGIELATNIGERLISEGAPGLHFITLNFARATREVLSNLGLAAARV
>A0A0S8BDV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium SG8_19|TrEMBL
MSSNGYLAGSNLERVLRAGHFAVTGELGPPQSADGEVIREKANLLKGYCDGVNITDNQTA
IVRMSSIGAGTIVIQEGLEPVIQMTCRDRNRLAIQADLLGAYALGMRNLLCLTGDHQNFG
NHPTAKNVFDIDSLQLVRMVSDMRDECIFQCGDAFKGREPRFFVGAAAAPFADPIDFRPY
RLAKKVKAGANFIQTQLVYDIPAFERYMDKVRELGLHEQTFILAGVGPLKSPGMARYMKN
NVPGILVPDELIDRMSAASEPWAGKSKDELTSEDKLARTKAWRDEGIKICIELTQQLQEI
EGVAGVHIMAIEWEEAVKPIVEGAGLYPRPEV
>A0A7S4I2K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vannella sp. CB-2014|TrEMBL
MAAGDPLFIDVTWGAGGGDPSTTDCTGSLCVCSTALNYCGLPSMLHLTCVDSSRDSIRNV
LEKAKETGIRNILALRGDLPVDLTVRPKTSDFKYASDLVAFIREEYGDYFGICVAGYPNG
HPDCDDFETDLMYLKKKVDAGADFIITQLFFEAKTFIHFVKRCREIGIECPIIPGVLPIQ
SYASIRHLMKLSKLRPPAAILEEIEKHKDDDVAIRKYGVSISVKLCREILESKAANGFHF
YTLNREVAVKEILTELGMWNPKGVASKEMPWLTSANEKRSNEGIRPIFWSGRPKSYLMRT
KDWDEFPNGRWGDSSSPAFGNLSEYYLFRAPPSSDAAQRRAMWGDSLESFAEIGQIFCNF
IQGKITRLPWSEEASLSSETKHIETQLMFLNTHGIFTTNSQPAVNGVPSTDPVYGWGEEE
GYVYQKAYLEFFIAPDVFEKLMKIFANYRSIRYHALNRDGKMFTNDEGGSVNAVTWGAFP
SKEIIQPTVVDPESFPIWKDEAFELWGEWRELYEKGSTARALIKEIRDTYFLVNVVDNDY
VKGNIFAPFQKLFEGE
>A0A6M0GEF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symploca sp. SIO2E6|TrEMBL
PLAASVILLQHGIEPVCQVACRDRNRIGLQGDLLGAQSLGIRNILALTGDPVKAGDHPDA
KSVFDLESVRLLKIIAKLNQGLAANDKPLTDGATDLFAGAAVDPQLKSWSGLQSRFERKL
EAGAQFFQSQLVTDFERLEKFMDKIAAGTDKPILAGIFLLKSAKNAQFINKYVPGVDIPQ
TIIDRLAAAADPLEEGIKIAAEQVKIAGQICHGVHLMAVKREDLMPQILDLAGISPLNQA
DD
>A0A7W1CNU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MFYGPCGGVRAGGSCEVDDRACPFVDAPLVRWAGADIVASAPALPQRADGLIVTDLRVRP
FDRRSTHDVVTLLRESSDLLLVGDHHSRPDYPPSFMVEVILASGGTPWVTLSCRDRNRVV
LEAELAALAALGVAGVHCVTGDARAPSVRTDVTQVFDLDSLRLTAAVRHAGLCASVAATP
AAPPVARRPNRIVEKERAGAQLCFVNHAGGVGAVASFVAACRAAGATLGFVPCVSVFTDV
RSLTVLTQFPGLVVDGDVAELVLGAADPRQAGIDAGVAQARAMLAIDGVVGVNLSGAATT
GAEVESAAIMAEIAGRLRAGA
>A0A7W0K5I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MARIADLLSQGRSFSFEFFPPKTPEAEITLEITLAELEVLKPSFVSVTYGAGGSTRERTH
DLVVSINQNTTMTAMAHLTCAAHTRHDLLEIVGRYAEAGVENILALGGDPPADLDLPAGD
LTYAAELVNLVREVGPFCVGVAAHPELHPKSPDRPADRRQLADKLGLADFAITQFFFRPD
DYLTMVEELAGLGMDKPVIPGIMPVTNLSSIQRMAAMSGAAVPPEVVSRVEAVAGDAEAV
RRVGVEMATELCRDLLDAGAPGLHFYTLNRSTATREIYASLGLSA
>A0A7Y3B729|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MKVTEHLERATDPFITFEIIPPTRGGKLSNLLGLIEDLMAHRPPFIDITSHAAEVVYEEV
ATGYEKRIKRKRPGTLGVCALVQNKFNIDAVPHILCEGFTRQETEDFLIELRYLEIDNVL
AIRGDSSGYEKRLEHGRSRNVYASDLITQIAEMNKGVYLEELLDASPTEFCIGAAGYPEK
HFEAPNLKADIARVKQKVDAGAEYIVTQMFFDNGYYFDFVDECRRQGIVVPIIPGIKILA
SQSQVVSIPRTFHCEVPAELADEVMNADESFASDIGVEWATRQTRDLLERGVPSVHFYVM
QSARLVNGVLANLDV
>K9J856|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenopus tropicalis|TrEMBL
MESYGRLPKSCREGSKSESGLRMVNANSSDSGTASCSSAEDSKESSRCSTPVLDVERHER
LKDKMRRRVEAGDRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSD
KETSSMVIASAAVNFCGLETILHMTCCNQTKEDITKHLHKAKHLGLKNIMALRGDPTGEE
WEEEAEGFNYAVDLVTHIRHEFDDYFDICVAGYPRGHPEAEGYDQDLKHLKEKVDAGADF
IITQLFFRAETFLTFINDCRAIGITCPILPGIFPIQGYGSLRQLVKLSKLEVPQEIMDVI
EPIKDNDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDVLKRLGMWKEDPR
RPLPWAVSAHPKRRVEDVRPIFWASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGELKDYY
LFYLKSKSPREELLKMWGQELSSEESVFEVFTYYISGEPNPNGHKVTCLPWNDDPLAPET
NLLKSELQKVNKRGILTINSQPNVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVTA
LIKVLKRYEPRVNYHIVNVHGQNITNAADLQPSAVTWGIFPGREIIQPTVVDPVSFMYWK
DEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLFKPYYLPVRSTQIQPCTCGSAVQAEG
VPKAAAEWQSPIWQFSSILY
>A0A3N5TQ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
AIKVMAADAFADGRISAVSITDNPGGNPALSPDVIGHDIFKVGMDVIVHFACRDANRIGM
ESRALQLAMMGMKNILALTGDYIGKGFAGQGAPVFDLDSVTLLVMLRLLGRRVQQAGDPD
MFFAGCAVSPFKNRRGEASAQYAKLCRKVAAGARFAVTQLGYDATRFKELMDVLHGLELE
LPTLGSVYVLTPVSARIMNAGQVPGAVVSNELMEQVILEWQDRRRGRDFAIERAARLGAV
LKGMGYRGIHIAGVHRGFDLVGRILDRMAQIEDQWRDFLDDFSPKRSKDSCSEGKKTPTR
SAGCSHIANLSLPDKLHLRFLKGVHNQFFNFDGRLAPLLHLMARRLGQRAGGRLLVQLFE
DPFKKLLLDCRRCGDCAIQHVAFLCPETQCPKHIRNGACGGSRNGCCEVYPERKCVWFRA
WERWNDSEQPGEMIADCIPPRLWELDGTSSWLNFHLRQDHQSASGEILQACRVIECRIPS
LLHF
>A0A846YM59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia flavorosea|TrEMBL
MHFFPADRTPIGHAVRTVPPVPASRTVVESLRTHSTKQVPFSVEFNPPRDADGEARLWRT
VRQFERMHPAFVSMTYGAGGSTKDRTARITGQLAQQTTLLPVAHLTAIGHSVAELRALVG
SYADCGIRNILVLRGDPPGDPLGDWHSHPAGVTYAEELVRIVRELGDFNVGVASFPQGHH
RSPDLETDTAFLAAKLRAGADYSITQMFFDIEHYLRLRDRITAHDPVEGAKPIIPELMPI
TSLRTVRRAVELSGRELPAAVLDRLRKAAGDGPQENREAVRTAGIEIATEMAQRLIDEGA
PCLHFITLNFAKATTQVLTDLGYEVTAAPRPAPRSRSAAVGR
>A0A846YMR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia flavorosea|TrEMBL
MNPTTPQLSTTPSVVQSLDRHAGAGVPFSVEFSPPRDEAGEQRLWRAVRTFERMHPAFVS
MTYGAGGSTRDRTVRVTGQLAQETTLLPVGHLTAVGHSVAELRSIVGAYADSGISNILVL
RGDPPGDPLGEWQKHPDGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLDCDTAYLA
AKLRAGAEYSITQMFFDVDDYLRLRDRVAALDPVEGAKPIIPELMPITSLRTVERAEQLC
GRPLPEPVLERLRRAAGSGAEEDRAAVRAAGIEIATEMGERLIAEGAPCLHFITLNFAKA
TSEVLTNLGYGVTAAPLSA
>A0A7V7F2D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MIIKRVGSPMAKNNNYRFQQSLKNPDEFTLTFELVPGRGGCSKEYARILALAENIAKDGR
FQAVSITENAGGVAALSPEVLGLEIQKMGLDVIVHFSSKDKNRNQMESLLLAWNRLGIRD
LLVITGDYPQKGYQGLPKPVFDLESVHVLNLISKMNKGDFSNTQQSDCIRSTSFCNGVAF
SPFKRLEAELMMQYCKLHRKAAQGADYLITQVGYDARKFQEILFYLKENDLALPILGNVF
IPNLTVSELMHQGKIPGCIITDRLYEIIKQEGQGPDKGKKARLIRAAKLLAIQQGLGYSG
AHLGGPGLKYEDLNFLLEQAADFLPRWQELVPEMNFWHEDGFYLYEKDLQTGLNRMPPSP
SKPTPKTAFSLNYHFARLMHILAFEPDGALYQPLKKTCLAFDNSRLDGALTHIEHVIKFL
LFECQNCGDCTLGELAFVCPQSGCAKYLVNGPCGGSRDGWCEVYPGKKRCLYVRIYERLK
SQGLTQAMQQGFVPPRNWALNNTSSWVNFYRGLDHAGKDR
>A0A0F5YD97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnoraphis robusta CS-951|TrEMBL
MSYFRTACLTPGEFIVTAEIAPPKGANPTHMIEMANTLKGRVHAVNITDGSRAVLGMSSL
ASAIILKGHGIEPICQVACRDRNRIGLQADLLGADALGIRNILALTGDPVKAGDHPDARS
VFDFESVRLLKAIQKLNNGTDWNDKALTDGATDLFAGAAVDPQSPSWSGLKSRFERKLKA
GAQFFQSQLITDFDRLDKFMTEVAAGVEPPILAGIFLLKSAKNARFINKYVPGVNIPESI
IERLEKAPKPLEEGVMIAAEQVKIARQLCRGVHIMAVKREDLIPKILDVAGIPALY
>A0A363TM47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRNILERMKESPLLFDGAMGTMIYERGVFINTCYDELCLSNPKLISQIHREYVEAGADVI
ETNTFGANRFMLRPYGLSDKAEAINRQAVRLAREAAGDSVFVAAAVGPCLRPDQIIPEER
VAEVEGAFAEQLGALAAEGVDLVVFETFTHLRELQVGALIARRLGMPVLASFVLNERGET
AVGTRAETMARTLSTDPNVDLVGINCGVGPAGVFDALQAVLPVTTKPVVVMPNAGLPRDI
AGRMIYLTSPEYFTEYAKKYIEMGVRGVGGCCGTTPAHIRTASRAVKSLSGVKKHVKVRA
YARQEPLVHVVASEKKSRLAAKLFAGEKAASVEILPPRSWDMTEMLAKVRRCAEAGVDAI
NIPDGPRASARVSPMIAALTILREVGIEPILHYCCRDRNLIGMQSDLLGGYAAKLANFLI
ITGDPPKLGEYPDVTGVFDVDSIGLTQVATNLNRGYDIGGNPISPPTGIFIGVGANPCAV
DLEREIDRYFRKIDAGAEFAITQPVFDADALLRFLDRVEGHSRTIPVLAGVWPLVSFKNA
EFMNNEVPGVVVPREILERMSRCRSKEEGHRVGIEIARKIIERISPRVSGFQVSAPLGNV
ETALAVLGRTAKPGAGKES
>A0A2K4BYN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus croceilyticus|TrEMBL
MSRLLNQLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADIIQT
NTYGANFEKLKTFGLEHKVKEIHKAAVQIAKRAANPTTFILGTVGGFRGLKQEELPLSTI
QYHAENQIDTLVEEGVDGLLFETYYDLEELTNIVTSTRRKYDIPIIAQLTASNTNYLVDG
TEINTALKQLVECGANVVGLNCHHGPHHMQRSFSHIELPEKAYLSCYPNASLLDIENKEY
RYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIAYIKTSVKDLKPVTSKNVIPINRKT
NRAITHTYKHNLTTKVKNGPTVIVELDTPKHLDTDLFFENIAKLDEAKVDAVTLADNSLA
TVRVSNIAAASIIRQRYDIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGASNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKIAAGMSYFITQPVYSKEKIKEVYEATKYLNTPLFIGIMPIVSYNNALFLHNEVPGI
KMSEDILNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQRIDYSLELAAY
SKAITQNKEAIS
>A0A7W1TYD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MAKVHELLAAGRCISFEFFPPRTDEAQRALEKALVELEPLRPSFVSVTYGAGGSTRARTR
EIVLDILAATSMTPMAHLTCVGHRREELVEILDGYREAGVANILALAGDLPADAPADQHQ
GDFRYALELVELVRERGPFSVGVAAHPEGHPRSSVRAEDRRHLAAKLAVADFGVTQFFFR
AQDYLQMIEELAALGVETPVIPGVMPVTNVGQVERFAALSGAAFPAELAARLHAAGDPEE
VRRIGVEVATALCQELLDRGAPGLHFYTLNRSSATREIYANLGLGPGVGAR
>A0A7C4BKP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MALSLLEEKLEAGEFVVTAEVGPPKGTDLTEMIHNIDLLKDWVDAINVTDHQSSVMRFPS
LGGCLLVKERGGEPILQVTCRDRNRLALQADLLFAYTRGIRNVLCLTGDSVEVGDHRGAK
PVFDLDSVQLLRGIKEMEEGHDMGGNPLKGAPQFYLGASVHVEADEMEPQLMKFEKKVMA
GARFFQTQGIFRVESLRRFMPYASQFGVKVLAGIIVISSARMARYMNEKVPGITVPNEII
EELSGTEKGKALQKGIEIAARTIRTIKEEGLCSGVHIMAIGNEKVVPELIEAAGLNGRAR
>A0A7V6C891|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLIKDIICSTKTTFSFEFFPPKDPAAWENLFLTIADLRTLKPSWVSVTYGAGGSTRDNTH
NIVVRIKKETDLTVVSHLTCVESYRDDIMMILERYNDNGINNILALRGDPPADHTNQKAS
SDGFSHAVDLVRFIKKHFPHMSIGVAGFPEGHPATPNRLVEIEHLKAKVDAGADYIITQL
FFDNRDFYDFRERCEIAGIHVPIIAGIMPIITRSGMVRMAELAAGARFPAPLIRAVKRAN
TDEQVEKVGIHWATEQVRDLLHNNVRGVHFYT
>A0A7C3K3P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSFKERLDSGKFAVVVELQPPKGTDLSEIYGNADLLKGRVDAVNVPDLQNAIMRLGSLSL
CALLKAKGMEVIYNLSCSDRNRLALQSELLNASVLGLQNLLLLKGDHPSVGDHFEAQPVF
DLDVIGLLGAAKRLQEGYDLVGNDLQGKPQFCVGTMVNATAKGHVLDLEVMDMEKKIRMG
VDFFFTNSVYDATLFEAFVKKVAHFKVPIVVGITLLKSVGMARYVNKHVEGASIPDPLID
QLMRASDKRQASVEIAGNLVKAIKPLCRGVQIIPIGWENLVPSVLDYAGL
>A0A7V1EG73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTFKERLESHKFVVVAQLQPPKGIDLSEIYGHVERLKGRVDAIHVPDLQHAIMRLGSLSV
CSLLKGKGMEVIYHLSCSDRNRLALQSDLLNAAALGLQNILVRQGDHPSIGDHFEAKPVF
DLDVIGLLAAVKRLQEGYDLGGNDLQGKPQFYVGTEANATAKGHALDLEVMDMEKKIRLG
VEFFFTNSIYDPSLLENFIKKVAHFRVPIIVGITLLKSVGMARYMNKHVEGTYIPDSLID
RLMKASDKQKESIEIASELIREMKPLVQGIQIIPLGWENLIPPLLDQVGL
>A0A432HR39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEFKSGSNLEKVLRAGHFAFTGECGPPTGANVEALKKKAGHLKGMVDAVNITDNQTAVV
RMSSWAASLIVMQEGLEPNFQMVCRDRNRLAAQSDVLGVYVHGIRNMLCLSGDHQKFGNH
PESKNVYDIDSMQLIDAVRTMRDEGKFINGEEIDVPPKIFIGAASNPFAEPFEYRVYRLA
KKISAGADFVQTQCIYNMDRFREFMKQAVDMGLHEKCYILPGVTPMKSVGMALYMSRSVP
GMDVPDDLIKRLRGAGKGKVAEEGIKFALEQIEEFKEMEGVAGVHLMAIEWEHRVPEIAE
RAGMLPRPIV
>A0A3N5IWY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
ISDMNRGLEYPGIKSIIRHQPGDFFGGAVVSPFKATEAEQMVQYYKLKKKIDAGAQFIVT
QLGYDARKFHEVLLFMKQNGFNIPLMGNIYILPFGAAKMMNRNDLPGSVVTDKLLADLDR
ERNDPDKGEKTRILRAARMYAILKGMGYSGVHIGGHNIKYEQVEEIIRQGEALTRQWTSL
IRYFDYPIDNGFYYFEHDPTTGLNRERPTQRQNRPLDVEVECNYGFSRLFHKMMFEPGKK
LYDVMKGLCVKVQGTQMEGIFHKLEHLTKVLLFDCKDCGDCALIDLAYLCPMSQCPKNQR
NGACGGSFQGWCEVFPKKRQCIYVRAYARLKKHGEEAHLTKDIVPPCNWDLYQTSSWINY
YLGKDHTSKKQS
>A0A661M5K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSLKEKIETGQFVVLGELEPPKGTDFSHMVAHANRVRNRLDAFVVPEMANAVMKASSLGG
CACLNREGLEPVFQACCRDRNRLALQADILAAGGLGIDNIMVVPGEEIAFGDHPRARAVH
DLSLTQALEMIRGLCSGKDMSGIDLQGTPDFLVGSNLNAGVTGGALDLELEELSSKIDLG
VRFVITTPVFDLDRFEKLLKRLDRQKIAVIPTVLLLKSAGMARYIDRNIPHISIPSDMIQ
SIQKASDKLKRCVEIAGELIAGLKAMEVGGVMISTIGWEDKLPLVLDQARLG
>A0A1I1MNG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudooceanicola nitratireducens|TrEMBL
MTTPAVSFEFFPPQNLEASFRLWDTVQVLAPLNPRFVSVTYGAGGTTRDLTRDAVATLHK
NAGLNVAAHLTCVNATREETLAIADSFAAAGVTEIVALRGDPPKGEGKFTAHPDGFANSV
ELIEALAATGKFTIRVGAYPERHPDSPSSDADVEWLKRKLDAGASEGITQFFFETETFLR
FRDRCDKAGITAPIVPGILPIENWKGMRNFALRCGANVPAWMDEAFEKAGRDGREDLLAT
ALCTEMCTDLLAEGVDKLHFYTLNRPELTRDVCHALGVTPEARLENVA
>A0A495K2L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia muralis|TrEMBL
MQRLAEPHPGPVPFSVEFYPPRDEQAEARLWRTVRIFERMGPAFVSMTYGAGGSTRDRTL
RITGQLARETTLLPVAHLTAVGHSVAELRAMIGGYADKGITNILALRGDPPGDPLGEWVK
HPEGVEYAEQLVRLVQELGDFNVGVASFPEGHHRAPDLDHDTKYLVSKLRAGAQYSITQM
FFDVDDFLRLRDRVTAMDPEQGAKPLIPGIMPITSLASVRRMVELSGSVLPEAVDRRLAA
AAGDGSEENREAVRAVGIDLATEMAQRLIDEGVPCLHFCSLNFAKATSEVLERLGMNVMA
A
>A0A3N5T6G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLEESLRKKGFVVTSEIQPPIETNVTDLIKSVNRIRGKVDALTVPDLKIEGLVADTMGT
CRILKEQNFEPILQTACRERSRVDIQEQLLKASEAGIENLLTFTEDYRITGDSLQEIMYF
HVDSGKLFSVIDSLQVGHDISGKEIPFKPKFCIGSGVDSSWGKKVPDMELREMEALAHLG
THYFLTTPVFDLESFHQFMNRVGLIQVPVIAEVILVRSAGMGIFLNKYVRPGLVPNHIIE
KLAKASDKEATSIEIIKELVKGLREVCQGVHFIPVGSTDRLSKYLEAVEVSSLKSRLYNP
A
>A0A1V5MDJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin419|TrEMBL
MTQLFFENRNFYDFLDKTDAIGINCPITPGIMPVFKADQIKRIASLCGASIPAKLVLLMD
KYGANDDDMRKAGIDYASSQIRNLIDNGVDGIHLLTMNRPKSTREILQNVGILPSDCQ
>A0A432MFL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tautonia sociabilis|TrEMBL
MHILDILAQHKTTFSFEFFPPKTAQASEDLFATISQLQELQPSFVSVTYGAGGTTRDRTH
ELIVRIQTETNLTAVSHLTSVCHSREELSAILDRYASSGIENILALRGDPPRNSAGYDRA
NDAFQYAEQLVRFIAEHPNRPDPRGFGIGVAGFPEGHPVTPNRLQELDYLKRKVDAGAHY
ICTQLFFDNRDFYDFRERCELAGITVPIIAGIMPVTSKPGMVRMADLALGARFPARLLRA
IERCAPEYSPELVAKVGIHWATEQCRDLLDNHVRGIHFYTLNKSDATRQIYENLGVKDSV
ALRTD
>G4MV96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)|TrEMBL
MHIRDMLAETEKTGKPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVTQAQTYFGLETCMHLTCTDMGVEKVNDALSKAYKAGCTNILALRGDPPRDKEK
WEAAQDGFNYAKDLVSHIRKTYGDHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGRVRERGITVPIIPGIMPIATYASFLRRANHMQARIPEEWLQRL
EPIKTDDAAVRIVGRQLVVELCRKILAAGIHHLHFYTMNLAQSTALILEDLDWLPSPNKP
LKHALPWKQSLGLGRREEDVRPIFWRNRNKSYVMRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLLGTNEQNRKKFGEPKSVKDIATLFVRYVQKEVDTLPWSESPLDAEAEQIRDDLID
LNLRGLITINSQPAVNGVRSTHPIHGWGPPNGYVYQKAYLELLVHPAIFEQLKERIHDHP
DLTYYAVTKSGNLHTNATYEGPNAVTWGVFPGKEIVQPTVVENISFLAWKDEAFQLGMEW
ARCHDQNTPSRILIQSMMQEWYLVNIVNNDFHAPRTIFDTLKGLTVPDIDTEIVPPALPT
AVPEAAAINGERNGERNGAQANGATAAVTAS
>A0A318AY55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. 3335mG|TrEMBL
MSELEEARRALDAPLFADLAGDAQVSFEFFPPKSEKMEAQLWDAVQTLAPLAPRFVSVTY
GAGGSTRERTHATVARIAKETSIPAAAHLTCVEATKDEVDAIARAYWEAGVRHIVALRGD
PPELGAKYQEHPGGYRNAADLVAGLRRIAPFDISVAAYPECHPDSADPQADIDNLKAKID
AGAARAITQFFFSPEAFFRFRDRAASAGIDAEIVPGILPVSNVAQTRKFAGACGAAIPSW
MDQLFEGLDDHPAARQLVAATIAAEMCRKLYAGGVRHFHFYTLNRAELAFAICHLLGLRA
NAKALEKAA
>T0C0W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteriovorax sp. BAL6_X|TrEMBL
MKVIEHIDKATNPLFSFEIVPPPRGKNISAVTDIVKQLLPFNPAWIDVTAHSAGAYYNEK
NDGSVERKIYKKRPGTVGICGVIQNRFKIDTVTHLLTQGFTKEETEDALIELNYLGIHNV
LALRGDALNYNKKYDLSRQRNFYAKDLVEQIDNVKKGIYLDEISNSLPLDFSVGVAGYPE
KHFEAPNLATDIKYLKEKVDAGADYIVTQMFFDNSKYFEFVDKCREAGITCPIVPGIKVI
KSMGQLSNVPRHFYVDFPDEFVNEATENPEHIKEIGIKWARKQTEELLNANVPSVHFYVM
NDSANVTEVLKGLF
>A0A2Z3RYM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantimicrobium photophilum|TrEMBL
MSNAPATSSTELNIGVPFSFEVYPPRNPDLREALNKTILELAATGPDFISVTYGAGGSSR
DATLDCVKFILANTDVEPMAHLTCVAESYQGANELVRTFLDAGVRSFLALRGDPPEGTQE
GEDFLGDLGSAAELTQLIHRVQAEREPFVFEEEPRWHAGATRLSQKREFVRIGVAAFPNG
HPQSRSKTQDIDVLLAKEAAGANLAITQLFFHADDYLSFAQKAKEAGLTMPIIPGIMPVI
SPGRLRRMIEISGEEMPSDLEIALEIEPTTEGQREIGVEHAVSLAKELIAGGAPGIHLYA
FNQSGPVVDVLRRLQ
>A0A534PPX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIVDMLRFAGERGEPVFSFEFFPPRNDAGVAALFETLHSLRPLAPSFVSVTWGAGGSSR
GRTLEMVTRIKRETEIEAMAHLTCVGVSRKELEEQLAVICDAGITNVLALRGDPPRGQRE
FIVHPEGLGHASDLIALAREVSEKRGVRLCIGGACYPEGHPETRELVRDLRNCKIKVEAG
AEFLITQLFFENRKYFDFVGRARAAGIEVPILPGIMPITNVEQIQRFTALCGAHLPHGLD
AALRSRGDDHEAALQLGVAYAALQCADLLRQGAPGVHFYTLNRSSATRAILAALRASAPW
HDG
>A0A423PQF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinisphaera orenii MK-B5|TrEMBL
MTNASQSSYSIEFFPPKGPKGEARLDDARARLAELGPAFFSVTFGAGGTTRSGTLKTVKR
CMETTGIPAAPHLSCVEGTRESIGEFLDNYKAAGVDRIVALRGDLPEGMDRPAGEFAYAN
ELVEFIRERHGDDFHIEVGCYPEYHPQAPSPAADVDNFVRKVKAGADSAMTQYFYNADAY
FNFCDEAAAKGVDIPIVPGIMPITNFEQVSRFSAMCGADIPRWIRQKMESYGDDLESVQA
FGQDLVARLCERLLAGGAPGLHFYSLNKADPTCWLWRELGLPTQDTASAANG
>A0A2D7NSI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
GAELLVSQFFLVNEFFLKWRDRLHRGGVRVPIIPGLLLPSSAEALFRMSKLCGVSIPGSL
RAKLERFADDPGALKEIGWNHLEAQTESLLREGIEGVHLYALNRLETVRRFSQMIQPVSG
RHDTYPENPGKYSIAENSKIPMTA
>A0A2T4IQ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium helmanticense|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKNDEMEARLWDTVTRLEPLRPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVNAARHEVDAVVQEFADMGVKRFVALRGDPAEGVGA
AYQPHPDGYANGAELVGALKGIGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEVEAA
GSAAA
>A0A2M8AKQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium CG_4_9_14_3_um_filter_33_16|TrEMBL
PSLNTDLKRLKEKVDAGADYVVTQMFFDNAKFFEFVDKAKQAGINVPIIPGIKPIAVKRH
LQLLPQVFKIDIPETLIQEVETCKDNNQVREVGIEWAIKQSKELLEAGVPVLHYYSMGKS
YNIKAIASQLF
>A0A644T910|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MKRISVELVPRDAEFLLTELESIKGRFPADTVNIPDLLRFDMRSWEGCHLVRKAGKEAIP
HIRAIDIDVRKPLPMAEYIYENNITEIVVLTGDRPQDMSRKIYPSTSVDVIRKFKQEMPK
IKVYAAIDQYRSSIRNEIEYAMRKLYAGADGFFTQPFYDLRFMEIYAEQLRNTEVFWGVS
PVLSENSVNYWEVKNNVVFPIDFRPTFEWNVKFAQDALAFVANQNSNIYFMPIRMKVAEY
LAAIFNK
>A0A7W0JUM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
CYDDLNLRQPDLVRDIHREYVRAGAQLLETNTFGANPLKLATHGLAGETERINSAAAGLA
REAAGERAAVAGAIGPLGVRIEPFGETSVDEARLAFRRQVQGLLDGGVDSFILETFSDVA
ELGAALAAVRELCDLPVIAQMTVGTDGKTHYGTDPAVFGPAVQALGADVIGVNCSVGPHG
VLEAIEKLARVVTVPLSAQPNAGLPREVGDRKIYMASPEYMASYARRMVEAGARLVGGCC
GTTPDHIRAMVGFVQSVSPRHSTTVVAIPVPAATPEAVPLAERSRIGRKLAEGRFITTVE
IVPPKGVDPAPMFEQVRRLKAAGVDAVNVPDGPRAQSRMGALLSALMIEREVGLEAVVHY
ACRDRNLLGMLSDLLGAAAAGIRNLLIVTGDPPKMGPYPEATAVFDIDSIGLTNLVSRLN
RGLDPGGNPIGQPTKFVIGVGVNPAAPDFERELKRFAWKVEAGAEWAITQPVFDLDQLDR
FLSRVESFRVPIVAGIWPLVSLRNAEFLANEVPGVTVPDAVLDRMRRASALGKDAALAEG
VRISQEMLTAVADRLQGAQVSAPLGKVPVALQVLEAAPIEPVASSGYTHET
>A0A7G7PTB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSAPTSLRVQAFLDAFSLEVSARAMPALGAEATRIPRGTTISIPWLASEDDDARLAAARR
VRELGFEPMPHLSARRIGSRAVLERFLQRAANEAGVAQCLVIAGDLATPAGPFADSASII
ESGLLERAGIKVVAIGGHPDGHPVLGSDACWQVLEHKCQSIEARGMAPMIITQFAFDADI
VLAWLHALRARGIHVPVLVGVPGPASIARLVRYAAMCGVGASALMLSRYGISIGRLLGSA
GPEVFVDRLAGGLTDAHGLVSPHFFPFGGIAQSLDWINQHRALPSVARR
>A0A3D1PXX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosipho africanus|TrEMBL
KKTNFCIGVAGYPEKHYESPNLKTDIKYLKRKIEAGAQFVITQMFFDVEKYFNFVKLLRD
EEINVKVIPGLKPILSYKSALKIPGTFYVDIPEELIEKLDNARTPKEEFWTGVKYTIKLI
EKLKENNVPGIHFFTMSNTDAIVEILKHI
>A0A542F9B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. A202|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTDAGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATDTTLLPMAHLTAVDHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWIRHPEGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAQFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGVEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARV
>A0A4V2EDY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas moorei|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A436HK47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.06.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A0C9U220|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerobolus stellatus (strain SS14)|TrEMBL
MKISQKIEQARKENRIWWSFEYFPPRTAQGLQNLVDRIERMRALGPEFIDVTWNAGGRTS
DLTSEMVKTCQSSIGIETCMHLTCTNMPKEKVEIALRDAKQHGCRNILALRGDPPAGSDE
WQTVEGGFEHGIDLIRYIHDNYGDYFDIAVPGFPQHQLLPPDERDQEMRWLKEKIDEGVS
FIFTQMFYDVDIFVEWVKSVRAAGITIPIVPGIMPIQTWNGFVRATQLAKTVIPKSYMEA
LEPHKNNDEKVRAIGTKLVADLCRRIIREDIGIKGLHFYTMNLERGTKMLLQELNFVPRV
ETIKPLPWRQSLTPGRREETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEEAHKLWGHPTTIEQIASLFARFCLGTLTSLPWSDQAPAAETLTISEPLV
RMNYYGFFTINSQPAVNGARSDDRVFGWGPSNGYVYQKAYLEFFVSTELLQALLPEIERD
PQITYYAINKRGDLKTNNHSDGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAFELGYH
WSNLYESNSSSRALLRDLMDTYFLVNVVHNDFKDSEAIFQPFFRVGEAKGLPLPNGINGT
NGTATPATNGTSITKD
>A0A2W6HR25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIEFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
AKLCQRLVEGGAPGLHFYTLNLARPTTSVLKLLHG
>A0A2J6HGV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinilabiliales bacterium|TrEMBL
MELSVTEHIERSEKTLFSFELLPPLKGHDFESTREAIDALIEFDPSFVNITYHQQEVVYD
HMPNGYHKKRTVRKRPGTVGIAAAIKYRYNLVVVPHIICGGFTKEDTENALIDLQFLGIK
NVLLLRGDPLPNAKVFIPEPEGNTYALDLVNQVMDLNKGIYLEKDLENTRSMDFCIGVGG
YPEKHAESPNMDSDLFFLKKKIEAGASYIVTQMFFDNKKYFDFVKRCRQKGITVPIIPGL
KPVSIANHLTSIPKTFNVDMPVELVKEIIKCKDNKQVRELGVEWAINQSKELIAAGVPVL
HLYTMGKTDNIQKIAKAVF
>A0A651DFK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
TGLDVVAHYACRNRHMVGMISDLLGAASGGVRNVLIVTGDPSPAGPYPDRTAALDIDSIG
LTNVLHHLNRGVDPGGHPVSPPARFVLGVAVGQHAPDADQELRRFRWKVEAGAEFAVTQP
VFDPAAAHRFLDRAFDEEVADVPSVRRIPILAGLWPLDSVRTAEFLHHELPGVRIPDAVM
ERMSAAEARGAEAAREEGVQIAVEAARALLPRVQGIHVSSPRGQAELGLEVVRRVRLLRE
GAAALSSAHTATGDGAG
>A0A2M9WCD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea rodasii|TrEMBL
MSFFHANQREALNQSLAELHGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFLSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPEELRGIARDYWENGIRHIVALRGD
LPPGSGKPEMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDNGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNAMFD
GLDNDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPTLTA
>A0A2W6ITL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLRG
>A0A1L8Q4Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVCNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQASHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>R6PVR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium nexile CAG:348|TrEMBL
MKIKDRLSENRVNISFEVFPPKTDAGYGKVLEATEEIAALKPSFISVTYGAGGGTSKNTV
KIASHIQNDLGVASLAHLTCASSTKEEVRQVIEQLKEQGIQNILALRGDIPKDGAFPIPN
HYKYASELIADIKSQGDFCIGAACYPEGHVESEHKSEDIAHLKEKVDVGVDFLTTQMFFD
NSILYNFLYRIREKGITVPVLPGIMPVTNGKQIARICELSGTILPERFRAIVDRFGDDPK
AMQQAGIAYATDQIIDLIANGIQNIHIYSMNKPEIAAAIMTNLSEIIK
>A0A5K7ZWE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina ovata subsp. sediminis|TrEMBL
MLNEKFVITIEVVPPDGPDPSELLKALGKLADLAFYGFSVATNPVAKPRMSAMALCALIQ
RHTGKPAILHLTTRDHNRLSLQGELWGARALGLQTVMVATGDFVALKDRHHTTTVRDADV
YDLVGMAREAGFKTGVVFDTHPESNGLPQAVGHLKRKVDAGAQFAVTQPVYDDAGADAIA
KATADINIPMIMGILPLRTPRHAEFLHSRVAGIAVPETLRHRMHAAADPVVEGAANAREM
LAIARQRFAGACIMPPFDHYEVLDEIL
>A0A1V3GHM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinivibrio kushneri|TrEMBL
MSYTHAGHIDALNQNIADLDGDINVSFEFFPPSTPTMEETLWNSVHRLKALKPKFMSVTY
GANSGERDRTHDIVKSIHDQTGIAAAPHLTCIDATEDELRHIARDYWQNGIRDIVALRGD
LPSPEKKPDMYAVDLVRLLKEEHDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAKMTNVRVPQWMHKQYQ
GLEDDPVTRQMVGASIALDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPLAVTP
>A0A553AQY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. M683|TrEMBL
MTAETSTTAPKISFEFFPPKTLEASFALWETARALAPMDPDFVSVTYGAGGTTRQLTHEA
VTTIQKNYGVNVAAHLTCVDASRAETLAIVQSYADAGVREIVALRGDAPKGADRFTPHAE
GFANSIELIEAIAARGDMTIRVGAYPEPHPDSTGGTDADVAWLKRKIDAGATSAITQFFF
EAETFFRFRDKCEKAGIDAPIIPGILPIQSWAGAKRFAAMCGTSVPAWADDAFTAAARDG
EGRETLLATAICTELCDNLIRGGVDRLHFYTLNRPGLTRDVCAALGIQPVRELKAVA
>A0A7X8DF29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MLTSVGSNLERVLKSGRHVVTAELGPPKHSSPHNIIRHTKKLKGYIDAANVTDCQSAVVH
MSSISAAFHIMNNGIEPVVQVTCRDRNRIAIQSDLLGAYSMGLKNVLCLSGDHQMFGNHP
SAKNVYDIDSIQLIQLTKRMCDEKLFFSGAAIKEFEPKFFIGAVANPFADPFEYQVDRLE
KKINAGAEFIQTQCIYDVERFARFMEMCVERGLHERAHILAGVTPLKSSRAAKFMQNRVP
GISVPEEIVRRLMKAEDQKAEGISICIEQIKFMKENVKGLAGFHIMAISWEEIIPEIMKG
AGIYQCS
>A0A542S844|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. SLBN-35|TrEMBL
MPGPGALRAPTLRPMTTGAGRSLGEIIREGGHSFSFEFFPPKDEAGEAQLWDAIRALEPY
RPTFVSVTYGAGGSTRDKTVAITGRIARETSMVPMAHLTCVGHTRAELEGILDSYVAEGV
SHVMALRGDPQEGPRADWTPTEGGLNYAVELVELARSRGDFRVGIAAFPEGHPSADSLDA
DADVLVAKARAGAEFAVTQMFFRASDYFSLVERVRARGVDIPILPGIMPILNLAAIRRQG
ELIGTSVPEDVVERISAYDGDPAAVRAEGIRIAAELCDELLAGGAPGLHFYTLNRSKATL
EIFEALQITV
>A0A198A5Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus oryzisoli|TrEMBL
MLKDKILRREPGIITYGMTPPKETHSLEKMAEISQKQCERLQKLQIDGLILYDVQEESDR
IDQDRPFPYLQTVDPTTYSKTYLSKLNIPKIIYRCVGKYSEEQLAEWIQDDLDAERFSVF
VGASSSKQDVQMGLPEAYELSRKLNDKLTLGAVVIPERHMKKDDEHLRMINKIASGSQFF
ISQATYNVEASKNFLSDYYYHCKEHNLEMVPILMNIAPCGSTKTLEFMKWLGISIPKWLE
NDLKYSQDVLDKSVSVSQQIFEEIFEFGLEKGIPIGCSVESVSTRKVEIEASIELVHEIK
AMMEKKMRSSFVF
>A0A1H1ICQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudovibrio sp. Tun.PSC04-5.I4|TrEMBL
MSEHSIDRRFRLNGASDISVSFEFFPPKSEKMEQLLWSAVKRLEPLAPSFVSVTYGAGGS
TRERTHATVSRIVQETALKPAAHLTCVDASKEEVNEVIQAYWDAGVRHIVGLRGDPAAGL
GETYAPHDGGYQTTADLVASIRSIGDFEVSVSAYPEKHPESPSWDVELDVLKAKVDAGAT
RAITQFFFDNDHYFRYVDRVRAAGITIPIIPGIVPVTSFKGISSFAKKTGASVPGWLAHR
FDGLDNDPRTRELVAAAVAAEQVMSLADDGVEDFHFYTMNKADLVYAICHMLGLREKRAL
TESVAA
>A1AMZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelobacter propionicus (strain DSM 2379 / NBRC 103807 / OttBd1)|TrEMBL
MRIADLIATRSPFVSLEFFPPKERSEWPAFFQAVEQLAQVDPLFVSVTYGAGGSTQSDTL
EIVSRLTRNLGLEAMAHLTCVGATPEAILEFLNQLSAAGVRNVLALRGDPPKDAPDNFLS
CHSLQYASDLVAYIRSVHPELGLGVAGYPETHPQAKSPQSDLDFLRLKLDNGGDFVITQL
FFDNTSYFDFVRRARDQGIEKPIIPGIIPVVSLKVIQRIVSLCGATIPARFLAELEQADR
DGGAAAVREAGVAHARRQAEELLAGGAPGIHIYTLNRADVVLELTRGLIP
>A0A5K7ZPP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina ovata subsp. sediminis|TrEMBL
MKSGSNLEKILRAGHFAFTGELGPPRGSNVEAVREKAKPLVGNVDAVNITDNQTAMVRMS
SWAASLIAIEEGLEPNYQMVCRDRNRLAMQADILGASALGIRNMLCLSGDHQQFGDHPQS
KGVFDIDSTQLIGTVKKMRDEAKFLGGADIDGPPQLFIGGAANPFAEPHEWRVHRLAKKV
AAGVDFVQTQCIFNMERMRTWVKEAVDMGLTEKVYILAGVTPMKSIGMARYMQLKVPGMD
VPNEIIKRLQGVDKKKVADEGIKIACEQIEEFKEMKGVAGVHLMAIEWEHKVPEIAERAN
VLPRPVV
>E6WAE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. (strain At-9b)|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMETTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWDSGIRHIVALRGD
LPPGSGKPEMYGSDLVELLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNAMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPSVAV
>A0A7Y7XYC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas gingeri|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASHNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLTQYKAAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGAHFHIEVAAYPEMHPQARNFEDDIQHFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7C3TLL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
KVTEHIAQAKGKTLFSIEILPPLKGQDIKSIFDAIEPLMEFKPPFIDVTYHREDFQIKER
ADGTKEKITIRKRPGTVGICAAIMNRFKVDAVPHLICGGFNQQETEDALIDLQFLGIDNV
LALRGDPIKFEGSFIPKSGGYSYASELVSQIKRMNQGIYVEEDLLNATPTNFCVGVAAYP
EMHMDAESMEIDMKNLKHKVACGSDYIVTQMFFDNKKYLSFVDNCRKNGIDIPIIPGIKP
LTTKKQLQILPKIFHLVIPEELVKEVEKCKDDEQVRQVGIEWAIQQSKELMQAGTPVLHY
YSMGKSDTVKSIASKVF
>A0A364K2I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoflavimicrobium daqui|TrEMBL
MANRSLREHLADSLLVGDGAMATYMFQQGISLGQCQEELVLRNPAFVAQIHQAYYQAGAR
MIETNTFAANRERLTRYGLDSKVVRINREAVKVARDAVGDDAFIVGAIGSICAGRVIDYD
EEEYRDMYEEQATALLSAGVDGILLETFLDLKEILIAVKTIRSLTDLPIIAQMSMLEVGR
TRDAYTLTEAFQQLADQGVDGVGINCRLGPMEILRSLEKTVIPESLIISAFPNAGRLGID
DGKIRYKSFPEYFGETAPLLIEQGVRLIGGCCGTTPEHIRQISQALEGKKPVLRKNPEPK
QLEIIVPEITETKPPKSSVVEQVKKKRTIICELDPPKDLDIRQFLTGAHRLSQAGIDLLT
MADNSLATARMSNIALGAILKSQLGIEPLIHVACRDRNLLGQQSHLMGLHALGIDQILII
TGDPTRMGDLPGASSIYDVTSFELIRMVKRLNQGISFSGKHLKKKAHFVVGTAFNPHVQK
LEAAVNRLQKKIEAGADFVMTQPVYDEESIDNIYEATKDLGVPVFIGIMPLTGYRNAVFL
HNEVPGIKIPKAILNRMEKHTDKQLGRAEGVAIARGLLDIAMEKFQGIYLMTPFSYWRMT
EELTKYIREQDQSRLAVEA
>A0A1G4EST0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLDLLSKGVVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPNFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMDGHKTKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>B0CHN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella suis (strain ATCC 23445 / NCTC 10510)|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGEKYV
PTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRAIPQ
FFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFDGLD
NDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAALEVA
>A0A660U634|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MKLSKLFNKKEFVITGEVGPPKGTHMSEVLKEARFLRPCVDAINVTDNQSAVMRLGSLVV
SAKIKEQGVEPIYQLTCRDRNRIAIQSDLLSASAMGIENVLCLTGDHIQLGDHFDAKAVF
DLDSVQLINVVRGLNEGHDMMGNELAGKTDFYIGAVVNPGADPLELQVIKMEKKIEAGAQ
FFQTQAVYDVSLFEKFIRMVEGFNVPIMVGIIPLKSPGMARYMNQNVSGIQVPESMIKEI
GSVDSNSRKKKSLEMTIKLINELKDMCQGVHIMPLGWWDLIPYIVKEFKEESKCYEETRK
AIAS
>K1Y6X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MKSGSNLEKVLAAGHFSVTAECGPPRGADPEVVRKKAAYVKGNVDACNVTDNQTSVVRMS
SLAGCLLIKEEGIEPLIQMVVRDRNRIALQSDLLGASAMGVRNILCLSGDHQKFGDDPQA
KNVFDIDSMQFIHLVKSMRDEGTFPSGKKLDGAPKFFIGCAVNPFADPFEIRVPRLKLKV
EAGADFVQTQCIYNMKKFKEYLELAKKQGLHEKVKILAGVTPLKSAGMAKFMKKMVAGMD
IPDEVINRIAAEPKEKQAEKGIEMCIELIQELKEMEGIAGVHVMAIEWEEKLHEIIGGAG
LLPRPVVE
>A0A2T7B801|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter turicensis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGLELKT
A
>C9PTG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. oral taxon 472 str. F0295|TrEMBL
MKMKVSDFLNKKAAAKALSFEVLPPLKGNGTAQLFRTIDRLREFDPNYINITTHNSEFVY
RQLDNGQYERDRIRRRPGTIAIAAAIQQRYGIPVIPHIICSGATVESTEYELLDLQFLGI
QNLLLLRGDKAHDERMFTPTPNGHAHTTDLIEQVNRFNEGFFADGTPMKHPGESFEYGVA
CYPEKHEEAPNLDMDIDYLLLKQQLGAKYAVTQLFYDNQKFFDFVAKARQRGVTIPIVPG
IKPFAKLGQLSVIPRTFHCDLPTALAHEIVKCKTDDDAKALGVEWATQQCRELYAHGVPS
IHFYTVSAVDSICEVAKKLL
>A0A0T0MBE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. Leaf394|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEATPGGHSSAMDLVNQINNLGRGKYLHDDQACDEHNKFCIGVAGY
PEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVTKAREMGITVPIIPGIK
PIATKKHLKLLPQVFKIDLPEDLINAVESAKNNEAVKQIGVEWAISQCKELLDFGVPVLH
FYSMGKSDNIKKVAGELF
>A0A512IMZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium haplocladii|TrEMBL
MPNANSHRASRDGFRPIRVSIEFFPPKTDEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVKETSLKPAAHLTCVNATKPEIDEVVQSYWDAGVRHIVALRGDPADGVG
STYKPHPGGYAQSCDLVAGIKKIGDFKVAVSAYPEVHPEAASLEADIDALKAKVDAGADQ
AITQFFFDNDVYFRYLDKVRAAGITIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLDNDVDTRRLVAAAVAAEQVIDLVDQGVNDFHFYSMNRSDLVYAICHILGLRSQAPKV
AERKAAA
>A0A4D7Q894|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus kaustophilus NBRC 102445|TrEMBL
MGLLDKLKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIAAMAKALSDRTPVTEKTVKRRAVSVS
VQADRPAPSPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKEQLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACGGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A852SYF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia soli|TrEMBL
MSCTEARFSFELYPPRTDRAAAALPGTIDRLAAARPDFISVTYGAGGSSRTASLDVLRYI
LEHTDVSAMAHLTCVGSSHEEAHRLIREFLDAGVRRFLAVRGDPPEGLAEGEDGIGDIRT
TAELVQLIHRVQAERAPYGELAVPGLPAQAVLEHREHVQIAVAAFPNGHPSSHSVSQDID
ALLAKQAAGANLGITQLFFHAEDYFHFAQRAAEAGVTFPILPGIMPVTSPARLKRMLELS
GEDLPSDLAIELEVEPTDEGRREIGIAWAARLGERLIAGGAPGLHLYTFNQHEAVLSVLD
RIGALPATSGIASTTPANPATEKEPA
>Q194R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces argillaceus|TrEMBL
MSGHLFTSESVTEGHPDKIADRISGTIPDALLREDPRSRVAVETLITTGQVYVADKVTTG
AYVPIAQLVRDAVLTIGYDSSAKGFDGACCGVSVSIGPQSPDIAQGVDTAYESLVEGAAA
GADIDELDRQDAGDQGLMFGCATDESPNLMPLPIELAYRLARRLTDVRRNGLPPTFARTA
RPGSPEDRAGRARVLWDTIRRGEALRPDFVSVTYEAGGSPRDRTVALTRRIAAETTLRPV
AHLTAVGHSVAELRQIIGRYADVGIRDVFALRGDPPGDPRGPWSPHFEGFTYAHELVEPV
RSLGDFTIRMAAFPERHPRSPDWESDIRHFVAKCRAGADYAITQMFFGPDGYLRLRDPAA
AAGCHIPIIPEIMPAMDVRQIRRFAELSAVAFTEDLAHRLEQARGNPAVGHRIGVDHATA
MAERLLAEGVPGLHCITLNRSTAALDIHRNLRTSRSLSVR
>A0A2H9RR25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon CG_4_9_14_0_2_um_filter_34_16|TrEMBL
MTIRYEANPPKVLPDVDTNESIKKFVEKIKIISKKCDAIHLTENVLGYQRVSPIKIGQII
RNEIPNLPITVSLRVRDKSESEISEFVDKCISVGFSGILILMGDPSQTGAKDSGQIPSLT
VKKLKEQGTKIDLYLSISNKPDFSKIGKKIDANPKGFMTQVIQNIEQVQNLHDNLKGFSI
IPILLYPSPKNEKSAKFLNLDLDAYGQEFEELVNKTHEITGDVLITSPNDFNGLNEFLEK
LSN
>A0A843CNB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosotenuis sp|TrEMBL
MIRYEINPPRVIQEKILSHKEVQISLNKIKKRIFDISKYCNGIHLTDSVLGIPRISPITT
GALIRNDGLKINITASLRVRDRNLISLTQSVYDAVLLGLDGLLVLKGDEPPAGPKDSKLA
PSEVVKYFKDLGFGKNLDFYLSIPSNPNFDKIQKKIDVAPTGFVTQVIQSSDQVFRLVDK
LKPQGFKIIPVIMIPSEKNAKSFTMLGIDYTKYQDRLIDFISEIYKSAGDVLITSPNDFK
AASRTLAKLKELKRK
>A0A6H1S855|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya zeae|TrEMBL
MSFFHANHQEALNQNLAELQGRINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPLGGGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFANMTNVRVPNWMTAMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPIASA
>A0A1S9EYF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium salinitolerans|TrEMBL
MVIKRITHKLPDISAAPIIPASIEASPAQVLGATDLAGLFPQGVRVYLTDTGAASQQRLV
EAAAHLRDLGYEPVPHLAARRIPSSAAFVEQVRRLAGEAGVTDVLVVGGGVERPVGPFAS
SMDMLSTGIFDRCGINQIAIAGHPEGSPDFNDDTAMAALRLKRDFAERSDAAMRIVTQFG
FDPARFIAWAEGLIASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LARGHSPESIVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGAADRSAS
PDSRAG
>A0A328L2B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. SRB_8|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNISKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTSIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPNFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A846S8F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus hyicus|TrEMBL
MSRLLNTLKDTILVADGAMGTILYSEGLDTCPEAYNLTHPEKVEHIHRSYIQAGADIIQT
NTYGANFEKLKAFGLEHKVRDIHHAAIAIAKRAAKADTFILGTVGGFRGLKQGDFTLPAI
QYHTEIQIDCLVQGGVDGLLFETYYDLEELLAVIQATRQKYDIPIIAQLTASNTNYLRDG
TVINDALQQIIHAGANIVGLNCHHGPHHMKNSFSHIELPHQAYLSCYPNASLLDIENNNF
KYSNNASYFGEVAEQLIHEGVRIIGGCCGTTPEHIHHIKTSIRGLKPVTHKKVIPIHKKR
ESTTPHATKLNLKERVTQQPTIIVELDTPKHLDTDRFFKNIAALDRANIDAVTLADNSLA
TVRISNLAAASLIKQKYTIEPLVHITCRDRNLIGLQSHLLGLALLGINEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNEGINTDGDALKRRTNFNIAGAFDPHVRNIDAAVRK
LETKLTSGMHYFITQPVFTKEKIVEIYEATKHLNVPIFIGIMPITSYNNALFLHNEVPGI
KMTDDVLEGFKAVAGDKLATYELSISICKSLIETVHQYFNGLYLITPFERVDYALELAAY
SKSITSTNQEVIL
>A0A842CFQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria marthii|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGQKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDKAYLAVYPNASLPEMQE
GKVIYQSDTDYFAHYGEIFRQEGARIIGGCCGTTPDHIRALRAGLQSTKPILEKEVRPIL
ELVPEEVEDAESGERLLDKVKERLTILVELDPPRTFDTTKFFEGAKALDAAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNAGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKAKIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYVQNKQQVQIVSK
>A0A3N9QKA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium CH30|TrEMBL
MNKRNFSFEFFPPKTDEGMAKLRNTRAQLAQFKPEFFSVTFGAGGTTREGTLAAVQDIRN
AGLAAAPHLSCIGSTRDNIRAVLNEYREHGIRHIVALRGDMPSGMVEAGEFRYANELVSF
IRAEHGEHFHIEVAAYPEFHPQARSAEEDMANFVRKVEAGANSAMTQYFFNADAYFRFVD
EVQARGVTIPVVPGIMPISNFGQLVRFSDMCGAEVPRWLRLRMQAYMDDSASIRALGLDV
VTELCDRLLSNGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A349MYV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus sp|TrEMBL
MAVDAGQQTLTDSEQRLPHSENLQTEHHFLHPSVGHKSILVEMDPPTTFKTEAFYRGAER
LRDAGVDAITLADNSLAAVRVSNVAVAAKLKLQYGIHPIVHLTTRDHNLIGIQSEIMGLH
SLGIDDILAIAGDPAKSGDVTSVGDVNALGLIKLIKQYNTGISPSGKDLDDKPNFCVAAA
FSPKITDGVLATNGIKHKIDCGADYLITQPIFDIGKVNELADAFNRCGVKIPVFVGVQPL
MSKRNADFLNSHVAGMSLPQSVLVRMAQAEIDGNEHETGLQIAEEIADAICDRFGGVHVV
TPFNRYKLAAKLVTHIRERERATVDNQ
>N1UX45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter crystallopoietes BAB-32|TrEMBL
MTRTAETAVPPSLSYELYPPAKPSAEDALLRAIDELGATQPDYVSVTYSGTPSRRRASIE
LIEHLVGATRLRPLAHLTCVGETRASLRQLVRQFVGLGVRGVLAMRGDLPAGPEVSRGEL
PFARYLVELIREVEESHSATLAGGRIAVGVAAYPNPHPESPSFQHDVEVLVSKERSGADF
AISQVYFDPADYVRLVTAARGAGVTIPIIPGVIPMSSVRRLERLAVMTGVRPDARLLHRL
ETASSDAERRRIGVAAAADLARAAFDAGAPGLHLYTFNDAPASVEVVEALDLPAIRTLST
AVSA
>A0A1Q4EKG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus sp. 0-1251|TrEMBL
MTERTFSFEFFPPKTTEGAEKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETVCEIQA
SGSEAAPHLSCIGSTEASIRDILNAYKRQGIRHLVALRGDLPSGTMDAGEFNYANELVAF
IRKETGDWFEIEVAAYPEVHPQARSATEDLANFKRKVDAGANSAITQYFFNADAYFNFVE
DARALGVAIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLASIRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPSTTIWQRLGL
>A0A414PIB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDQVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQPNFEVN
>A7V495|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides uniformis (strain ATCC 8492 / DSM 6597 / CCUG 4942 / CIP 103695 / JCM 5828 / KCTC 5204 / NCTC 13054 / VPI 0061)|TrEMBL
MQDFCQSDKDNEREMRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYI
NITTHRSEYVYKDLGNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETE
YVLLDLQFLGITDLLVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMK
VTNTPFSYGVACYPEKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERAR
QAGVTIPIIPGIKPFKKLSQLSIIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQ
CKELIAHGVPSLHFYSVGATDSIREVAKQIY
>A0A2N8KCM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter pulmonis|TrEMBL
MSDSISPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLRDILQAYKSEGVRRVVALRGDLPSGMGGDAGELRYANE
LVTFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVRKVRAGANAAITQYFFNADAYF
DFVDRAQAKGVDVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPMAVWRELSLQG
>A0A1F8TJ42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_19FT_COMBO_62_14|TrEMBL
MKSGSRLERVLRSGRFAVTAELNPPDTADPQAVYDRALVLASVCDAINATDASGANVHMS
SVGMCALLTRAGYEPVMQVSCRDRNRIAIQGDLLGAAAMGVRNLLCLTGDGVQAGDQPES
KPVFDLDSISLLRTARVLRDEGRFLSGRQLEAAPKFFLGAAANPFAPPLEFRPLRLAKKV
EAGADFIQTQFCFDMKLMRRYMEAVRELGLHERVFILAGVGPLRSAKTAEWLRSRVPGVV
IPDEVIHRLRRVPLEKQREEGKRLCIEIIQELQEIDGVSGVHVMAYRQEELVAEIIEESG
LLPRRRSGRMPQALETEDASN
>A0A221KDL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vitreoscilla filiformis|TrEMBL
MRNLPLSLEFFPPKTPEGVTKLAAVRQALYVLKPQFCSVTYGAGGSTQDGTLSTVQAILD
EGHSGAPHFSCIGASADLIRDKLAQFKAMGVERIVALRGDLPSGYGSFGEFRYASDLVRF
IREETGDHFHLEVAAYPEMHPQARCPQSDLQAYATKVKAGANSAITQFFFNADAYFRFVD
DARRLGAEVPVIPGIMPITNSSGILRFADGCGAEVPRWVRLRLQSFGDDTASIRAFGLDV
VTMLCERLIAGGAPALHFYTMNQSATTLEISRRLGLLA
>A0A423MGU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A3P1C5U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pacificus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1T3A6F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTKYQQAGIQRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A432U163|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thioglobus sp|TrEMBL
MKTSFEFFPPRTDKGKQTLAQVRQELSTINPEYFSVTFGAGGSTQDATLETVLDIQANDS
VSAAPHLSCIDSEKAKIIELLDQYKAADINRLVALRGDIPSGVRDIGDFHYANELVEFIK
SEYNDHFHIEVAAYPEMHPQAKNIQTDLEHFANKVKAGADAAITQYFYNADAYFRFRDDA
QKLGIDVPITPGIMPITNHTQLLRFSNMCGAEIPKWILERLKLYENDLTSLTLFGTEVVS
NLCQTLKDQGVDSFHFYSMNRTEPSLSIAKHLL
>A0A2E4Q1S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia sp|TrEMBL
MSASEHPSGISFEFFPPNTEAGREKLKGVRDQLAALEPEFFSVTYGAGGSTRERTFNTVQ
SVSASGICTAPHLSCVGSDRGELREILAQYREQGVKRLVALRGDLPSGMGSRSELRYANE
LVEFVREETGDHFEIAVAAYPECHPQADNYHSDLENFARKMQAGADIAITQYFFNADAYF
HFVERARAAGIQQPIIPGIMPITNYTRLARFSDSCGADIPRWLRRQLESYGDDSESLQAF
GTEVISRMSQRLLDGGAPGLHFYTLNQAEPCLKVLENLGISSR
>R6ICZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phascolarctobacterium faecium|TrEMBL
MKIIDLLKNEKVCISCELFPPKAGTELQNALNIVSDIAEVGPHFMSVTYGAGGTSVGQTV
AIARAIEASGRPALAHLTCIDADEAKIDGVLAQMRAAGVQNVLALRGDAVNGNDGDFAHA
SDLMGKIKKAGDFCVGGACYPEGHPEAGSLDRDIVNTRRKIDSGCDFLVTQMVFDNNIIY
NYMYRLLRHGIDVPVVAGIMPVTNAKQINRICELSGTKLPANYRAIVEKFADDPEALKQA
GIAYATGQIVDLIANGLKNIHVYTMNRPEIIGGIMKNLSEIVK
>A0A833E8F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrodictium sp|TrEMBL
MRAPPPHFYNGLTCQKHHSNLQAIHMRTKRKFKASGYVVCWCVKLVEVWVELEPTTRKEK
LEKKLEKIKTYKVDALDIPDAPLGVPKAFAPLMACYIQAVYGVKVIPHIRLLDINTNALL
NIVGGLLFCGVDNFVILQGDQPKYGNPISELNTDDALQVIRSKYGDRVSVGCLVSLRKNV
SEIVKRIVKDYDFFLLMRAVNENLEKIKVLRQIRADAKLIAYVIVCESENCKRLRSMLEG
QPIVNVERVDEHLNNLVEYVDGILLSSPGSIDTIVKVLELLNEIGIL
>A0A0F4TXD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A4R8V1D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium flavum|TrEMBL
MTAPTPNACDARPAFSFEVYPPKSVAAASALTRTIDHLAAAGPEFISVTYGANGSSRNSS
LDVLRYIKDHTSVDAMAHLTCVGSSHTEASRLIREFLDAGIRSFLAIRGDAPQGADEGDT
TFLGDLHSAGELVQLIHRVQIERVPYIETVIPGLPGARGVKTERSKVRIGVAAFPNGHPN
SRSVTQDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLLPILPGIMPVTSPN
RLRRILQLSGEKLPAELSIQLEVEPTDEGQRQIGIDYAVRLGQDVLAGGAPGLHLYAFNQ
HDTVLKVLEGCGALPVPAAMP
>A0A2I1KQB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIHSKRPDLPILGACYPEKHPEAVTLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKISEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A2R4UNA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter junii|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIQRFVEKVQAGANAGITQFFFNPDAYFYFI
ERLAKSGINIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>W5FX66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Triticum aestivum|TrEMBL
MKVIEKIQEAAANGRTVFSFEYFPPKTEEGVENLFERMDRMVAHGPNFCDITWGAGGSTA
DVTLDIANRMQNMVCVETMMHLTCTNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFSCALDLVEHIKAKYGDYFGITVAGYPEAHPEVILGEEGATEEAYSKDLAYLK
RKVDAGADVIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNL
GLIEESKLSRTLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWGDSRNP
SYGALNDHQFTRPRGRGKKLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPE
TTIIDDQLVKINSKGFLTINSQPAVNAEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLG
QLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWSRGWACLFPEGDSSRELLEQIQKSYYLVSLVDNDYISGDLFAAFKEI
>A0A2S5DXI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia contaminans|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVM
>A0A6B1F2I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MATTSRKKDNFMESLAHRILVCDGAIGTELRKRIPAYLQCVDACNISTEHAEKVTAIHRA
YTDAGADVIQTNTYQANREALAVHGLAEQVKEINTTGVLLAREAVSETSYIAGSVGQISF
RSLDTTVPSTKIIRQTFKEQMDALVEAGVDLLVLETFVSPKQAEVATKQALTYGVPVIVE
ISGISGGTVGTGLDVRVFAQELEQLGAHAVGINCRGPHDLVEAMELLAPVIKVPIAVQPN
AGNPRVEQGEVAVSYTVEAEVFSDYVGKLVELGANMIGGCCGTTPAYTAKIRQAIAGREP
VQRESRIFVLPKIRSVGARSSRPYDNPVQQVFETRERIVSVETRANTFPQLRAMLKEAKG
LAAIGVDLFDVTDNSGAAVNIGAVGTAYRLQQATQIPTLIHWTTRSRNLISMQSHLLEAE
ALGIRGIVALSGDHPKAGPYETASLVPDVRGAVQLMKLIARLNQGELADGSSIGEPCGFY
YGGGFTIAENLQPHVKHLANKVAQGANFAYTQPVWTYEDILHTQQATEHLGIKMLYGILP
LTSFRSASYLRDNLGLYIPQFIVDKFRDLGDTAGQELGMQLCLELVRNIRNQDECEIDGI
YLIPPARMNWKNRARVISEIVKTYR
>A0A2D2LWV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella osloensis|TrEMBL
MTTPFSFEFFPTKTDDGQTKLLATFDELNALKPQYFSVTYGAGGSTRERTLGIVKALSEK
SDTPITPHLSCIGDDKAKIGELLDYYKSLGINRLVALRGDLPSGMVGLGELPFAVDLVKY
IREHSGDYFRIKVAAYPEMHPQAKSFDADIQNLLNKYHAGATEAITQFFYNADSYLYLRD
ALAKKGVTQDEFPIIAGIMPITNASNLIRFADGCGADIPRFIRKQLADYGDDKKAIRQFG
FEVMVNLCERLIAEGVPSMHFYSMNQVSPNKQLIEALGLV
>A0A2W6TRA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVHQINDLGRGKYLHNQDEVCDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVTKAREMGITVPIIPGI
KPIATKKHLKVLPQIFKIDLPEELINEVEKAKNNESVKQIGIEWAINQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A2C9JU61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Biomphalaria glabrata|TrEMBL
MPDIKNPEAIDGNSASEQNEHSINGTNHTSNSDHECAVTKPQNGANILSRKPSDSSSISS
SPGESRAASPVSSRKKYVSLIERIRKRIQGKTPFFSLEFFPPRTQSGAMNLISRFERLSE
GHPLFCDITWHPAGDPSNTEKPTSSTCMAGVMLNYCGIETMLHMTCVGMSTDTIKENLHK
AKDLGIRSILALRGDLPEGDDHWKETEGGINYATDLVKLIKEEFGDHFVICVAGYPAGHP
DCRSYHEDLQHLKEKVDAGADFIITQLFFKPETFLNYVKDCRKLGINVPILPGILPIQAY
QSLRHIVKLSKLEVPLEIITAISPIKDNDEAIRKFGIDHSVDMCRALLKSGIVPGLHFYT
LNREVAVKEVLKQLGLWNEKAPRTLPWKKSANHARCDEDVRPIFWRCRPNSYVYRTSEWD
EFPNGRWGDSRAASFNDLKYYHLFYLKSQSPKEELLQMWGEELTCEEDVWSVFVNYLTGQ
PNKQGVKVKRIPWDDDEIVAETSLIADKLACINKRGVLTINSQPRVNGASSTDPIVGWGS
PNGYIYQKAYLEFFTSKESVDALKHILPRYPLVNYHIINHTGAADYTNCDEHQPIAVTWG
VFPGKEILQPTVVDPEAFKTWKDEAFALWLETWGSLYPAESKSREVLQHIHDNYYLINLV
DNEYPKETVLWDIVEEMLKMAGRTGPEQVSCEAST
>A0A0K6BZJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A098Q3F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis pv. vasculorum|TrEMBL
MISTDTPRLASTMTDAYSLEVSIKDIGALTNAAPRILPGSAMFIPYLPSQNDAARLAAAQ
MVRGLGFEPVPHLSTRRIGSFEQVQAFIARLVDEADVTRCLVIAGDRSTPKGSFPDSVSL
IETGVFERAGIRTIGVAGHPEGHPIMRTADQWDVLERKCRSIQERGMAPLIVTQFGFDAD
LVVTWLEALRARGMSHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLVSRLTQAHGDIRLHLFPFGGIAQSAEWVAQYRSRTAPQDRTRAVRVDRA
>A0A4P8LKD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLYQRNRLRRRPGTVAVAAAIQNKYNMTVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGHHHALELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIHWLKKKVEAGAEYAVTQLFYDNKKYFDFVERVHQAGIHIPIIPGIKP
FKKLSQLSMVPKTFKVDLPEELTQEALKCKTDEEARKVGIEWCINQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A4S8UF13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVENVAVEDDDTPVANGNGDKKAKARRRSSLANS
APQNRVVVDKTSRSASSGSATFEAFDDGAGVPGEDPPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVE
FFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLL
EA
>A0A7S3GGD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Palpitomonas bilix|TrEMBL
GMKIHEAIKEKAQSGETFISFEFFPPRTDEGVKNLYARFGRMKEQHPVFVDVTWGAGGST
SDLTVEICEKAKHEYGLEPNMHLTCTNMVPQKVEDALKKCRESDIENIVALRGDPPAGHE
MWSVTEGGYACALDLVKFIKKEHGDEFCISVAGYPEGHPNAISFVPTDYQPASDAEAKRM
AKVEPCEEYPEGGWFVCKDENFAKEIAYLKEKVDAGGNVVLTQLFYDADLFIDFVKACRD
QGITVPILPGIMPIQAYPGFRKMTKFCKTKVPADLDAKVEELKDDVEGLKTFGVEYVANM
CQKIIDASEDGVKGLHFYTLNLEKATYAIMDKLGLKKSVPDSSQ
>A0A7H9W8H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae|TrEMBL
MNYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGF
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A7S3G8X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Palpitomonas bilix|TrEMBL
MKYFLSKQYSNAKKLHTIIEVFKPATREGENSLMERLNRLATLNPALFSISSQNHQHENN
TLSLTQLVREDVCAEVQVHLQCDEPLEILRANIASAKAFNVRHFLFFVLRQPQALVQEGG
EVSHDSVAIEEALKKMRQLLHLLGEEQSIGVMVPYCDTRDEQIWASVARLACPGIDYVVL
PMIATTQSYSARCNLLTKHGVRCPIVPAIVAAALNARSLESLINSTTAGRDEEWQCIVRQ
LLEIEEQIVLSGRTHRLNVHASEQGRDSSSLSAQKSEERASSTLRSFHSTTIHRIKKQKA
EAIQAFWLSRCVELVEGIQECGSPGVYLVSLNLESVVKKVAEACGLREGGTLPWRPRLEA
GQGEQIRPIHWANNPKSYMKRTRGSGNMSCGTWARAIREGDVVFSSHDAGASDQHKSERL
AMWGISLRTHDDVFATFLKYLQRRIRFLPWCDSIAPETDGEIKDTLLKMNSAGFLTINSQ
PAVDAAPSSHPVFGWGPRKGGFIFQKAYVEFFTAQDNLARIVKLCSERENLTYFAANAED
HFVTNCTSSRGTIAVTWGIFPGYEVVQPSIVDRGAFLLWKEEAFSKWTSEWGCLYQFGSP
SRKIIEDLHDSYYLVCIVDNQYSESTLMSDLVHLLPGK
>A0A1C5RNA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Blautia sp|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPGTIEHLMKYKPEYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLEQYLAEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A1L7CIV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium flavescens|TrEMBL
MSPRLSASVPLDHLNESEEFSSSASQPHSRVALSFEVIPPRHDADETKVTQLLRVLEAYN
PDYIAVTSSQRSGWLEGTAAFIARVAQETTMRPLAHLACTAGTAQELDGWIDKLVDSGVR
GLLALRGDVPPGGMPPGHLHHADELVRLIRRKEAEQAARFAAGRLAVGVACYPNGHAESA
SADEDFDVLLAKQRCGADLAISQLFFDAEDFLRFSQKARLAGVRIPLIPGIMPMTSMRRL
ERMGQLSGLKVPPRVSARLAAATSPEEEHEIGMELTAELARSVIDAGITGLHIYTHNNAE
VTQDLLERIGVTS
>A0A2T3RQ56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia albertii|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPESGKPEMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A6P7IEX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parambassis ranga|TrEMBL
MVNHFQRGGSSCQSCKSDSSGASNSGGESSKESSRCSTPVLDADRSDRLRDKMRRRTESG
DHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
INYCGLETVLHLTCCNQTKDKIIGHLAKAKHLGLKNIMALRGDPVEAEWEEEEGGFNYAV
DLVKCIRSDFDDYFDICVAGYPTGHPEAQSYDKDLRHLKEKVDAGADFVISQLFFRADTF
LKFLDDCREIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPLEIMEVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGKVPGLHFYTLNREVATIEVLRQLGLWTEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSPKEA
LLQMWSEELVNEESVFEIFTCYITGQPNRSGHKVMCLPWNDESLAPETNLLKDELEKVNR
RGVLTINSQPSINGKASTDPIVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRV
NYHIVNVHGHNLTNAPDFQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFTLWIEQWA
KLYEDESPSRMIIKYIYDNYFLVNLVDNDFPLENCLWQVIDDMFELRDAPPEPFNDTTVA
ENP
>A0A3G5LA35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pestis|TrEMBL
MERKLSFEMNSAKNEKEMENIFKLIEFTDTLDPIYYTVNTEIGSSVWSDTYRTVIELREK
TDVPLIPHITINNKKEREIMQIIEKYINVGICEFFVIRGDKHVYDQDNPINYGVELIELI
RRSHKHIGIKTSLYPDFHKETTEVKEEIDWNERKYQLGVNEFISQLTLNTNALDFLSHWV
DKERPFTPSIMPLGNFSFIEKFTSSNSIDYPLWIKKFANSKSNSNEDKENIGIEIIRFLC
REYLNQRERLHVFTLNKVDVMKKIFQ
>X5DEF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Draconibacterium orientale|TrEMBL
MKVIDTINQAKKTVFSFELLPPLKGNDVSRLHKTIESLTEFDPKYINITTHRDEIEFKEL
ADGSIVKQTVRKRPGTVAIAADIQHKYGIPVVPHILCGGFTKSETEHVLIDLNFLGINNV
LALRGDGLKNQHVFQPTENGHSNANELVKQIKDLGKGKYLDADLKNNKPLDFCIGVAGYP
EKHFEAPNMEQDMLYLKQKVDEGADYIVTQMFFDNQVYYDFVDKCRAMGITVPIIPGIKP
INLKNQLTVLPKIFSIDLPQELSKELTKCKNNDDARRVGTEWAIYQSKDLVARNVPSLHI
YTYGISDNVSEIVKAAF
>A0A8G6UAC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPNFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPVIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A104JIA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia gladioli|TrEMBL
MKPIELSLEFFPPKTAEGADKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLSAAPHLSCIGSSKDNLRAILDQYRSHGIRQIVALRGDLPSGMGEVGELRYACDLVRF
IRAEHGDWFHLEVAAYPEYHPQSRSPKQDLQHFADKVKAGANSAITQYFFNADAYFRFVD
DAARLGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGADV
ITAMCDRLIKQGVPGLHFYTLNLATPTRVVCERLGLSG
>A0A1X1H732|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2T3QJW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium damselae|TrEMBL
MQPITNYQALSLQDSELRVRYNDVTRGVYFIGTTPPKTSTDLSDVDGIADKLVDRIKDLA
FDGLIVYDIQDEGSRISKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSEPEVFN
QWLNEAWEQYQVRDIVLVGSPSTQNQVSLPLHEAYKTIADNEHPFFTGGIMIAERHAKKG
NEHQRLIEKYQQGCNFFISQAIYDTQATIDLLTRYAIECQEKGLKPQRIILTFSPCGSAK
TLEFIEWLGVSVPEATSLRILNADNPLHESIKMCCNSLNQILEAVVEYDLPLGLNIESLT
NRKEEIEGSILLYKLLRSTMDMYLAQHEFRKQQGLKKAF
>A0A2S6A8S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia nova|TrEMBL
MSFDNVRGRSTPGRPSRTPSGTPSVVGQLGRRPDGTIPFSVEFNPPRDAAAEARLWRAAR
EFERMHPAFVSMTYGAGGSTRDRTARITGQLARETTLLTVAHLTAVGHSVAELRSIVGSY
ADAGIRNMLVLRGDPPGDPLGEWRKHPDGVEYAEELVRMVCELGDFHVGVASFPQGHYRS
PDLEHDTRYLVSKLRAGAEYSITQMFFDVEHYLRLRDRVAAYDAEQGAKPIIPELMPITS
LRTVQRAEELSGRPLPARVMQRLEQAAGNDPEANRNAVRAVGIEIATEIGQRLIDEGAPC
LHFITLNFAKATTEVLTNLGYTVTPAAVSA
>A0A5N3YUU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVPPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A0A1DP69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides simplex|TrEMBL
MTTGAGRSLGEIIREGGRSFSFEFFPPKDEAGEAQLWDAIRALEPYQPTFVSVTYGAGGS
TRDKTVAITGRIARETSLVPMAHLTCVGHTREELGSILDAYVAEGVSHVMALRGDPQEGP
RADWTPTEGGLNYALDLVELARSRGDFRVGVAAFPEGHPSAGSLDADADVLAAKARAGAE
FAVTQMFFRASDYFGLVERVRARGVDIPILPGIMPILNLSAIRRQGELIGTSVPDDIVAR
ISAYDGDPAAVRAEGIKVAAELCDELLAGGAPGLHFYTLNRSKATLEIFEALQITV
>A0A821YBD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood1|TrEMBL
MEFTLDDNQTVPDTHKMYDNEINLESMHNANIFKRIESEGANLGARGCSLQPVKYVSLID
KILKRIADNDRWYSLEFFPPRTASGAANLIGCFDRMAAGQPLFCDITWHPAGDPASNKET
SSMMIANTMLNYCGIDTMLHLACHGATKAAMLEYLYKAKDFGIRNLLALRGDPPVGEDWD
PAKSDFRYAIDLVRFIRQHFGDYFIICVAGYPQGHPDSTSYEDDIAHLKEKVDCGADFII
TQLFFQPETFIKFESDCRAIGITCPIIPGILPIQGYASLRNIVRLAKLDVPKEILACIEP
IKENDEAIRNFGVQACLDLCRTLLDSGKVNGLHFYTLNREFATIEILKRLGLWLEDQPLR
ALPWKKTSYSHARSKENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGVLADYH
LFYMKIDATRDELLDEWGRELTCEQDVWQMFACYIGGEKNHQNKVVRHFPWTDEELSSET
TLIKNNLVDFNKRGILTINSQPAVNGKPSSDPIVGWGTPNGYVYQKAYLEFFTSADNIPA
LQAVLKKFPNVNYHFLNKSGGINETNADDEQPIAVTWGVFAGREIIQPTVVDPVSFMIWK
DEAFSLWTERWGKLYEPESRSHAIIDKIANTYFLVNLVDNDYPQGSCLWQVLDSMFEYQK
LSNQPIDS
>A0A0Q0HPW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. zizaniae|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDGKDDLRNLLAQYREAGIKRIVALRGDLPSGMGMASGELRHANDL
VTFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A7Y4P714|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium ulcerans|TrEMBL
MSASHIPAAYQRSITEVLKMPSPGRVPFSVEFMPPRDTSAEQRLWKAAEAFHDLGTAFVS
VTYGAGGSSRERTMRVAHKLSKLPLTTLVHLTLVEHTEAELVEILDDYAAHGLSNLLALR
GDPPGTNPMAEWVATPGGLEYASELIELTKKNPKTSHFQVGIASFPEGHYRAPSLDADTE
FTLQKLRAGADFSITQMFFDIEHFLRLRDRLAKADPEHGCKPIIPGLMPITSIRSVRRQM
ELAGASLPRELEKQLLDAAKRDEESHKEDIRKVGIELTTQMAEKLIAEGVPDIHFMTMNY
VRATQEVLHNLGMAPAWGTDHGHDAVR
>A0A330G480|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter hyointestinalis subsp. lawsonii|TrEMBL
MLKDKIKENKPGILLYGITPPKINLSKDEAYQIAKKQLERLENTGIDGLVIYDLQDESSR
NNKKRTFEFCGTIKPEIYHKEFLKLSYPAVIYKAVGNYTKEEFANFLNTYNNDMLSVFVG
ASSKNDLLKFNLNEAYQLKKEQGRNVTVGGICIPERHEKKGDEDLRVASKIVKGCEFFIT
QAVYNIENAKRFLDDYANLGIKKVPIIFTFTPCGSPKTLEFMRWLGISVSKQFEDRLFES
DDPLSASVELSLDMFEFLYKYGRAKGVSVGANVESISTRKVEIEASINLLCGIKNIIQNE
KECNLEELIQSASKFYE
>A0A4Z1AAL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira jelokensis|TrEMBL
MHISQVLQKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEQTGLTIVSHLTCVGSTKEEIREILKRYEKSGIHNIMALRGDPPKGQTEFQKT
ENGFGFAGELVGFIKKEFPNMGIGVAGFPEGHPSTPNRLKEIEFLKWKVDQGADYICTQM
FFDNNSFYDYVERCEIAGIKVPIIAGIMPITSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDSYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRKIYESLGIRNFDTIV
>C9LVY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sputigena (strain ATCC 35185 / DSM 20758 / VPI D19B-28)|TrEMBL
MSKVSLELVPRDEAALREELAQTKKYEGKIDLINVPDLLRLPVRSWEGAAIAGETFPAVP
HIRAMDIDITKPLPMADYLREHAIREVLVIEGDAPQNMAHTVYPTESIDVIRKFREEMPE
IRVFAGIDQYRGSMRQEDYRIRRKLQAGAVGFFTQPFFDRRFLAMYADMLEGIEVYWGLS
PVTSQRSESYWETKNQVVFPKDFEPTLAWSIAFARDVLAEARAKGEHVYLMPIRTGIDEY
LGGIFAEG
>A0A1Q2CD79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus flavus|TrEMBL
MPTPPPTPGSVRELLDAATGPLFSFEFFPPRTDDEEPVLWAAVEALAPLDPDFVSVTYGA
TGSRRDRTIHATRRIASSGGPLTVGHLTCVAQSKAEIAEALAAYRDVGVTNILAIRGDMP
GGGDWVRHPDGLANATELVSFIKEQGDFCVGVAAFANPHETTLDPELDAQILAAKVEAGA
EFAITQLFFEAERYAELVARMRAMDCEVPIIPGIMPLTVITQIERFAALSGCPLPERFVG
ELRALGSKEEVRAHGLAEAVRLCRELLDAGAPGLQFFTQNRSKATREVLAALKGRV
>A0A1V8QC06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium adolescentis|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVDEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREKRPNLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCQSRVPEKLSVLLDKWGGDTALLKEAGITY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A4V3V989|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria rosea|TrEMBL
MTPRPTARPAPPSLSYELYPPRSAASADMLLRTIEELEPTRPDHVSVTYSGDEQRRDSSL
ALLDHLLARTSLRPLAHLTCVGSTRAELEQTVAALVRRGVRGVLALRGDLDPGAEPGELR
HAGELVELVREVEQRHTAALAAGRLAVGVAAYPTRHPESPSFRHDVEVLLAKQRSGADFA
ITQVYFRPQRYERLVAAARAAGVTIPIVPGIMPVTDPRRLRTLCRLAGLAPHPGLAAALE
DAPGPAERHRAGVAFAARLARAALDAGAPGLHLYTFNEHRAALDLLEHVDLPRVPHVPVA
LEDLLLPA
>A0A3Q9LZ20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar 43:a:1,7|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A374NX93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum hallii|TrEMBL
MQTNPQDILKTLSLSFEVFPPKKWEDFPGLYETLDELKGLHPEFISCTYGAGGSNSKKTA
EIASHIENELGIRSIAHLTCAALTEDKLLSTIENFKNAGIHSVLALRGDKPFDMSEEDFA
NRQYKHPSEIIPILKKAGFRVAAACYPEKHYEAPSMEEDLHWLKHKVEQGADALISQLFF
DNDAFYRFMDAADQKGITVPIHAGIMPITSAKMINTTINLSGASIPKALSDLIATYGENP
SDMRKAGIEYAARQINDLAEQGMHYVHIYTMNHSETAKEICGLIK
>A0A061BBE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyberlindnera fabianii|TrEMBL
MATVKEKIAALGKDDVFLSLEFFPPKTEPGIRNLLARMERMSAMSPLFVTITWGAGGSTA
EKTLSLIQTASKEMDLTTCMHLTCTNIDKSIIDDALAKAKLAGVRNILALRGDPPRGEEY
FVPNNADFQHAVDLVRYIKEQYGDYFCIGVAAYPEGHCEGADCSEQSVEKDMPFLKEKVD
AGADFIITQLFYDVEKFLTFEQLVREQVSPDITILPGLMPINTYQLFHRAAKLSHASIPD
SIIAKFPENIQHDDDKVKSVGVEVLKDMIHELYSRTNGRIRGFHFYTLNLEKAIAQIVET
SSLLNTVIDRNDKDGDYIMDTDISFPPGVKKKERRSSSTNTTNKVLVDRVRKEAAFEDAA
SFKLSVPTKKEILAISTGEGTLGRGATWDDFPNGRFGDSRSPAYGEIDGYGPSLKIANKK
AYELWGYPVDTGDISKVFMNYLSGTVDALPWSELGLSPETAIIQEQLIALNKRGYFSLAS
QPACDGAKSDDKIFGWGPKGGYVYQKAFVELFVPREDWETKIKPTLDSNLGIVSYYVGDS
KGGFETSMGAQSSNAVTWGVFPDREILQTTIIEEESFKAWRDEAFSIWLEWGKLYKKDSA
SWKLIQNVHSSYCLVSVVCHDYRNENGLWELLLK
>A0A3C2BYC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp|TrEMBL
MSPPSLIETHPNLAETAPVALSYELFPPRSPAAAESLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPEELAEIIGDLLDTGVRGILALRGDRPKD
GAPPVAGSLHYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYANLISRARRAGVTIPIIPGVMPLTSLRRVTRLGELTGVE
PAPELLARLAAADSDAERLRIGVKATVDLAKAALDAGAPGIHLYTFNEHQSALEVLDKLA
LPRHSRSVGRRSAALRRQLAS
>A0A415S1J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides eggerthii|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESAFTPESNGYLHAIELQDQINQFNKGIFVDGSEMTVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMENGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTKEVLKCKNDAEAQQVGIEWCVQQCKELMKHHIPSIHF
YSIGAVNSIKEVARQIY
>A0A4B9HX09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes serotype 1/2b|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLGDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDDVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A2N0DS68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas baetica|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARSGADSAITQYFFNADSYFY
FVDRLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A6J0E5D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peromyscus maniculatus bairdii|TrEMBL
MVNEGSSSGSEGSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGA
VNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCQQ
RQEEITGHLHRARQLGLKNIMALRGDPVGDHWETEEGGFSCATDLVKHIRNEFGDYFDIC
VAGYPKGHPEAESFEDDLKHLKEKVSAGADFIITQLFFEASTFFHFVKACTEIGISCPIL
PGIFPIQAYSSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSG
LVPGLHFYTLNREVATMEVLKQLGMWTEDPRRPLPWAVSAHPKRREEYVRPIFWASRPKS
YIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFE
VFEHYLSGEPNQHGHTVTCLPWNDDPLAAETSLMKEELLRVNRLGILTINSQPNINGKPS
SDPVVGWGPSGGYVFQKAYLEFFTSPETVEALLQVLKKYELRVNYHIVDVQGKNITNAPE
LQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIH
DNYFLVNLVDNEFPLDSCLWQVVEDTFELLNRHTAKREAQAP
>A0A5D2NRQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium tomentosum|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPGNDGVATPEAYQNELAYLKRKVDAGAD
LIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKEMKAASFF
SKG
>A0A6B1HCU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSTDSAAAQTSAAPPIDGVADATRELALGASVELTPRQVTAADNLAKDLPLGTRVYVPFV
PGADWQDTVGACERIHASGMIAVPHLVARSVANRAELDDRLRGLAEAWVTEIMLVAGDRA
RPVGAFRDTLDVLDSGALVGHGMTRIGIAGYPEGHPAVDPAPLDAALAKKREYAAATGTE
MWMVSQFAFEPETVIDWLDAIWRADDTIPVRVGMAGPARLSTLMAFAVRCGVGASASALI
RRPGVLRLLNPHLAPDGMLNALGRHRVASPESPLSGIHLFTFGGLPQTSRWLRAMAGVGT
AHVVDFHDAKANGER
>A0A4J2FGQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A661FLV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDSQKQYKPVFSFEFFPPKSEEAAGKLAIVRDRLVELNPRFFSVTFGAGGSTQAKTFETV
LEIQKETSVRAAPHLSCVGSTRENIRSLLNQYKENDINQIVALRGDIPSGMRDAGEFCYA
NELVEFIREETGDHFHIEVAAYPEFHPQAANATADLQNFKRKVEAGADSAITQYFYNADS
YFQFVESCEKLGLDLPIVPGIMPVTNYTQLARFSDMCGAELPRWMRKRLEAYGDDRDSIR
AFGQEVVTRLCERLLEQGAPGLHFYTMNQSKPILAICENLDLGGSGDE
>A0A5J5JN01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium lushaniae|TrEMBL
MTGKDIPGLEEARDTIPAGTKINVTFLGNEDLDMRVAAAKAVADMGFVPVPHISARRLSS
QGQLEEFLGRLQEVGATDHVFAVGGDPAEPEGPYPDSLSVIRSGILQQYGVKEVSIAGYP
EGHPDIASDVLWRHLEDKSAALKEQGLDAVILTQFAFDTDPVTTWIQAVRDRGIDTEIRI
GTPGPAGVKRLIGFARRFGVGANAMIVKKYGFSLTNLMGTAGPDRFVTDLAALLAQNPAS
GNVRLHFYTFGGLLATSKWAGEYVAARS
>A0A0A6TX36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. phaseoli|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRLGVEIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A099F828|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus halophilus|TrEMBL
MSQFDQDPNAIRRYAPPPEGHVSGSKLELALRAGHFAVTAEMNPPDSADPQDVFKAAQPL
ADVADAINATDASGANCHMSSIGICALLTRAGHGTVYQISCRDRNRIAIQGDVLGAAAMG
VRNVLCLTGDDVGAGDQPGAKPVFDFDSLTLIRTIRTMRDQGVFLSGRKITSPPNLFIGA
AENPCVDPLEWRPDRLAKKVAAGAEFIQTNYIFDMPRFQAFMSRVRDLGLERKVFILAGV
GPLASAKAARWMRGNVPGIHIPDQVIARLEKAENPGEEGRRICVELIQQLREVAGVAGVH
IMAYRREHLVADIVREAGIAREQRPA
>A0A6P3QAW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pteropus vampyrus|TrEMBL
MDYPKPQVLPARHRCPSLGKQAWEAGSMRFSVPPSIRNSAMVNEPGGHGSLNPRSEGSGS
GGESSKDSSRCSTPGLDPERHERLKEKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRFD
RMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCHQSREEITGH
LHKAKRLGLKNILALRGDPIGDQWEEEEGGFRHAADLVKHIRSEFGDYFDICVAGYPTGH
PDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQG
YHSLRQLVKLSKLEVPQQMKDVIEPIKDNDAAIRNYGIEQAVSLCQKLLASGLVPGLHFY
TLNREMATTEVLKRLGMWTEDPRRLLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELASEESVFEVFVRYLSG
EPNQKGCKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNVNGLPSSDPVVGWG
PSGGYVFQKAYLEFFASRETVHALLRVLRKYALRVNYHIVDVKGENITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSRIIIQYIHDNYFLVNL
VDNDFPLDNCLWQVLEDTFELLNTPSSE
>A0A126UKE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A2E9ZJV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MATFPEKLATDEFVVTTELTPPKGIDLDKLLNKAEFLAPFIDAFNLTDSHSSRMSLSPIA
VASRLLDFGYEPILQITTRDRNRISLQSDMLGAAVLGIKNIVCMGGDPAHFGDHPDAKPV
FDLSTTELINAAYQLSQGQDLAGNALQGTPTFNIGAVVNPGADDLDREISLLEDKVAAGA
WFFQTQAIYDAGVFGDFMNRVSHLPIKIIAGILPIKSVKMAMYMNEKIPGIQIPNHLMAE
IDSSKDVKSTSADIAAKTIRAIKDSCAGVHMMAIGAESQIPIILQQAA
>A0A178TDC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus flavithermus|TrEMBL
MGLLDDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIDAGAEVIQTN
TYGANYVKLARYGLQDDVKQINEAAVRLAKQAAKGRAYVLGTIGGLRSTNKSTISLEEVK
RTFREQLYVLLNEGVDGLLLETYYDFEELQTVLSIARQETTLPIIAHVTLHDIGVLQHGM
PLADALCQLEQLGADVVGLNCHLGPYHMLRSLEEVPIPTRAFLSVYPNASLPQYRDGRFV
YETSEQYFEETARAFRDQGVRLIGGCCGTTPKHISAIARALSDRTPVYEKKVKQRHTIVV
QEAEQTSAPSLADIARTRRSIIVELDPPKKLGLTTFLEGAKALKEAHIDALTLADNSLAT
PRISNVAVGTIVKQQLNMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRL
EKKIECGAQYFLTQPLYSEKQIEDVYEATKHLATPIYIGIMPLTSARNADFLHHEVPGIT
LSDDIRARMAACANDPIQATKEGLAIAKSLIDAAFDLFQGIYLITPFLRYDMTVELVRYT
HEKERLKKERTVYHG
>A0A6B0ZA14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSPPAKISLEFFPPRTDELTAMLEASLKRLLPYGPLYCTVSYGAGGSTRAGTARWVRRIR
QDFGIDCAPHLTHVSHTRDEVREIVRGYVAQGVRRMIALRGDIPADGIPDEVRKRGYSST
VELIADLRAEGINEVMVGTHPEHGGGDSASLRRHLEFVKQKLDAGATLAITQFFLDNHRY
YRLRDVFAGAGMEHLLAPGIMPLHNYRQVFSFAGKTHVEVPAALRERFQQAGEDPDAVRQ
IAEGFSLDQVRDLAENGVERFHIYTMNRAPLTAAICEALGSSAPGPQS
>A0A0U2W2C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus naphthalenovorans|TrEMBL
MKADLREALRQQLIVGDGAMGTYLYQMGFPVGISYEELNLLKPDVIMDVHRRYYEAGARL
IETNTFSANREKLSKYGLEQEVEAINRAGVDLARRSVGSDAYVVGAIGSIRAGKRKNVRT
AKVKDDLKQQIEVLADTPVDGLLLESFYDLEELLIALKLIRKISSLPVICQFATEGTGST
HDGIPLDEAFRRLLAAGADVVGFNCRSGPNGLMRSLERIAGMEAAPPFSIFPNAGIADYV
DGRYTFAATPSYFGETARKFVDLGARIIGGCCGTTPEHIAAIASSLRGYVPDPAAIRKLT
ENVREPRPERIAEPVQVSDRPPAAPPVQSEPTIVDLVKERPTVIVELDPPRDLDIEKFMQ
GASALKKAGADALTMADNSLAVTRMSNLALGSLVQERIGIRPLIHIACRDRNMIGTQSHM
MGLHALGIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGVSFSGKPLKKKA
NFIVGAAFNPNVKYLDKAVRRLERKIESGADYIMTQPVYNAELIEKISEATRHLNVPIFL
GIMPLASGGNAEYLHNEVPGIQLSDEVRQRMSGLKGEEGRAMGVQIAKELLDVALSHFKG
IYLMTPFLAYEMTVELTKYVWQKAGRRDFHLYPLEK
>A0A848VCM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia sp|TrEMBL
MPDDSRSALRNCLQSGHFAVTAELTPPRAAELQSLSEAAALLKTAVTAVNLTDGAGARVR
MSSLAAAIHLRQQGIEPILQVTCRDRNRIAIQSDLLGAAAFGINNVLVISGDGIREGDDA
TPVFDFNSRTLLAAIKKPGMSGDADAASSPTTSGNFFCGTADMPCEPPTDWVPDALLAKQ
RAGADFVQTQYCFDIDLLRRYIGRLADHGLTEQLYFLVGLGPLRSADGARWMRDNLFGTV
MPDGIIRRMEAARDPREEGIEICAELMQEARDIPGVAGVHLMAPGNHTAIVAAVQLAGLI
>A4E8J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens (strain ATCC 25986 / DSM 3979 / JCM 10188 / KCTC 3647 / NCTC 11838 / VPI 1003)|TrEMBL
MRVDEVFKQAASQGTAPISFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GAATAPIAHMITSEFDTPSVAHLTCVGRSHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A7K0LZ86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MEQMTVSVEFFPPKDDAGETRLWEASSALETIAPDFISVTYGAGGSTRDRTIAITKEITK
RTGRGTVAHLTCVGSTKAELIEILNQYKSAGIKSILALRGDPVGGPTANWVTTAGGFDYA
DQLVELAVGQGGFDVGVAAFPDGHPASSGDFSRDIDVLIRKEQLGATFATTQFFFESSKW
ENLVSKLGARGSKLPVIAGILPITNVKQLQRMAELGGTPIPDKISKLFSEISEDPDAVRK
AGVELATKLCEEMIALKVPGLHFYTMNTAAPTLEICANLGITARG
>A0A6I3HU62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARIGDLLAAGRTFSFEFSPPKTTAGSMSLGRTIAELESLSPSFVSCTYGAGGSTRENTR
DTVLWIERETNIPAMAHLTCVGHTRHEIEDIIATYTAAGIQNVLALAGDPPKDPADARPS
DYMYALDLVEHLCEIADLSIGVAAHPEGHPRSPDLATDRRLLAEKLRVVDFATTQFFFDI
DHYLSLVNDLADLGVTKPVVPGIMPCTNIAQVERMAELSGAAFPQWLRERLESGTSPEDV
RRIGVEAATELCAQLLDAGAPGLHFYTLNKSTATREIYAQLGLPVA
>A0A202BBD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium violaceum|TrEMBL
MTQTPRTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGQAAAPHLSCIGSTRENIAAILNEYRGNGIRHLVALRGDIPSGMVAAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLANFVRKVRAGADSAMTQYFFNADSYFRF
VDEVRARGVDIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRLRMQSYYDDTASIRALGL
DVVTELCDRLLQGGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A0C7N8N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorella glycerini|TrEMBL
MKTESKLEKLLSQGHFVVSGEIGPPKHANPEGIKKHTAQLKDYVDAMNLTDNQTAIVRLS
SIAAGVHVLQAGGEPIIQMTVRDRNRIALQSDLLGAYSLGMRNVLCLSGDHQSFGNHPTA
KNVHDVDSLQLIKIVKDLRDEKKFACGEELKGNEPRFFIGAAANPFADPFEFRVLRLEKK
INAGADFIQTQCIFDMERFERFMAMVRERGLHKKAHIIAGVMPLKSAKAAKYMQQSVAGM
IVPDEIVNRMEKAADPKAEGVAICVEQIKHLKTIEGVAGVHIMAVMWEEIIPTIVQEAGL
YPRPKAE
>A0A537XLR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTEVASPSPDGHRAPKTPAISFEFFPPKTEEMERNLWDTINRLAPLAPNFVSVTYGAGGS
TRERTHSTIARILTETSLTPAAHLTCVDAPRADVDDVVARYHEVGVRHIVALRGDPAGGI
GSAYTPHAQGYRSSADLVASIKQAHSDIEVTVSAYPERHPESASFDADIDMLKAKVDAGA
GRAITQFFFDNDLYFRYLDRVRARGIEIPIVPGILPVQNFKQAANFAKRAGASMPDWLAQ
KFEGLDDDAETRKLVAAAVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPKSA
QKAA
>A0A7C2LI61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MKRERFLEILRGGVLIADGAMGTMLQRLGLQPPYELTNLVQPDAVRQVHRSYIEAGARLI
ETNTFGANRVKLATHGAGHLVREMNLAAVRLAREAAGDVPVIVAGAVGPVGKPLAPIGQI
APQEAGEAFREQIEVLLEAGVDLVMLETFTHLDELRIALEQLRALDSEIPVIAQKAFIED
GETLAAGLPAQVARTLEEWGVDVIGANCVVGPQRMVGILQGMASATSLPLSVMPTPGLPQ
YQRGEVTFEAQSDYFAQYGEQFARIGVNIIGGCCGTTPTHIRAVAERLQGVKPRPRRAPA
KVKEVVKPEDLPQAEPSQLAGKLGRKYVIAVELDLPRGLDVTKVLDGARSLKEHGVDVID
ISDGARARLRMNPIAISHLIQEQVGIEVMMHFACRDRNLLAIQADLLGAHALGIRNILAI
TGDPALIGDYPTATSVFDIDAIGLVRILRRFNEGVDLAGNSIGMRTAFTIAVAYNPLAYD
QKAEDERLQRKASEGAHLVYTQPIFDIAVLERASETVNRLGLPLLVGVLPLRSARHAEFM
HHEVPGVLIPDPIRKRLEGLDDADARKYGLDVAKEFALQARKLSQGIYLMPPFGNHKVAE
AVIDILAE
>A0A3E4MK71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea formicigenerans|TrEMBL
MTCKIRDILKDQTPQVSFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKN
TVSIASHIKDDFGVTSLAHLTCVSSTREEVHQVIDKLKEKNIDNILALRGDIPKDNAFPL
PNQYRYACELIEDIKQQGDFCIGAACYPEGHVETEHKKDDISNLKTKVDCGVDFLTTQMF
FDNNIFYNFLYRIREKGILVPVLPGIMPITNKKQLRRSMELSGTAVPQRFLAIIDRFGDD
PEAMKQAGIAYATDQIIDLIANGINHIHVYSMNKPDVATAIMNNLSAILKVED
>A0A412MGZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea formicigenerans|TrEMBL
MTCKIRDILKDQTPQVSFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKN
TVSIASHIKDDFGVTSLAHLTCVSSTREEVHQVIDKLKEKNIDNILALRGDIPKDNAFPL
PNQYRYACELIEDIKQQGDFCIGAACYPEGHVETEHKKDDISNLKTKVDCGVDFLTTQMF
FDNNIFYNFLYRIREKGILVPVLPGIMPITNKKQLRRSMELSGTAVPQRFLAIIDRFGDD
PEAMKQAGIAYATDQIIDLIANGINHIHVYSMNKPDVAAAIMNNLSAILKVED
>A0A7Y2X578|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTDHIKAAKGKTLFSFEIIPPVKGHNIRELYDNIDPLMEFNPPFIDVTTSREEYVYID
RNGLLDKKLTRMRPGTVGICASIKHKYNVDTIPHVLCGGFSKEETEYLLIDCHYLGIDNI
MALRGDAMKDEKYFEPSEGGHEYASDLVKQIDNLNHGIYLHEVIETEDCADFCIGVAGYP
EKHMEAPSLMSDLKWLKYKVDLGANYVVTQMFFDNKKYFDFVKAARDMGIDVPIIPGIKP
IAIKKHLQLLPQVFRIDLPQDLVDAVEACKNNKEVRQVGVDWAIAQSKELKAAGVPVLHY
YSMGKSSNIKAIAEAIF
>A0A1L3Q4W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus halophilus|TrEMBL
MPSAFKEKLLSDDFVITSEISPPKGVDVSSAFEEAGLIKDYVDAFNVTDNQRAVMRMSPL
AMGHLLKEQGLDVIMQFTCRDRNRLALQSDLLGAYAMGMENVCIMSGDYPTKGDNPGAKP
VYDLDSVQLLGAMNRLEEGYDIAGNPLESSPSFTKGAVCNTEPDQPLQLMKLEKKAHMGI
DFFQTQAVYDIGHFETFMDSISHMDVPVLAGLIPLKSAHMARFMNEKIPGIRVGDELIAR
MESSTDPAEEGLLICAEQIRELRKVCRGIHLMPIGHYSHITALFEMAGLHEKN
>A0A154DPX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKHHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KKAKSFLIKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
SGKEFSPEITHFSCQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKDKLIPTVPLETRGTSSWKNWYLATEA
>A0A3E4FA69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea formicigenerans|TrEMBL
MTCKIRDILKDQTPQVSFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKN
TVSIASHIKDDFGVTSLAHLTCVSSTREEVHQVIDKLKEKKIDNILALRGDIPKDNSFPL
PNQYRYACELIEDIKQQGDFCIGAACYPEGHVETEHKKDDISNLKTKVDCGVDFLTTQMF
FDNNIFYNFLYRIREKGILVPVLPGIMPITNKKQLRRSMELSGTAVPQRFLAIIDRFGDD
PEAMKQAGIAYATDQIIDLIANGINHIHVYSMNKPDVAAAIMNNLSAILKVED
>A0A3I7XGL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALADIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A078HWP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica napus|TrEMBL
MKVVDKIKSATEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNAICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGEDK
FVQVEGGFACALDLVNHVRSKYGDYFGITVAGYPEAHPDVIEADGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAFGIHFATEMCKKILAHGITTLHIYTLNMDKSAIGILMNL
GLIDESKITRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYGTLSDYQFMRPRARDKKLQQEWVVPLKGIEDVQEKFKELCLGSLKSSPWSELDGLQPE
TKIINEKLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSRDKLD
TIVEKSKAFPSITYMAVNKAGNWVSNVGEADVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYFLVSLVDNDYINGDIFSVFA
>A0A1C3JZ20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orrella dioscoreae|TrEMBL
MEVSAKDIPALTAVAPRLPPASTISIPYLAGEGNAARLAAARAVRELGFEPMPHISARRV
ASLAELQAFVARAAAEAGVERCFVIAGDPSTPKGPFPDSFSLIDTGVFERAGIKALGVGG
HPEGHPVMSVADRWEVLERKCRGIEGRGMAPSIVTQFVFDADVVLTWLEALRARGIAHPV
RVGVPGPAGVAVLARYAAMCGVGACASMLAKYGISIGKLLGTAGPDRFVDRLAAGLTPAH
GTVSLHFFPFGGIAQSVGWIEQYRATRKQNTR
>A0A1V0NUZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYLDKTQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSLISSLFKINT
>A0A693DU68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLNKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A1E8E547|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter towneri|TrEMBL
MTKQVPISFEFFPSKTDVGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLSTISDFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYASDLVR
FIREHSGDHFHIEVAAYPEMHPQADHFDQDIKNFVTKVNAGANAAITQFFFNPDAYFYFV
ERIQKQGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIIKLCERLIAGGAPSLHFYTMNNTEPTRQLVTDLGLA
>A0A2E4LEM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MSDVLAKKHAIQAFMQETSVEVTPAGARAVKNFSTILKPKMTVYVTFLPGSDFRDTLETV
CRLKNEGYCPIPHFAARSIESEKIFEESLAKLRQEANVNEALLIGGGVDIPVGPFTASIE
ILRTGLFDKYGFNRIGVAGHPEGSPDITPKECEQAIREKNEFNQHTDADLYLATQFLFEA
KPLFQWEKTIRDQGNKLPIHVGIPGLATIQTLIRHAKQCGVGPSVRFLKKNPVDMLKMSL
RNTPFSSLVKAPSSNPSKLIFDIVTGIASDQDCLIEKCHLYPLGGLQKSVDWLYQIQDGN
FSVSWDDFNVH
>A0A0F2DFD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALQNMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIKFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A6B0W1J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Holophagales bacterium|TrEMBL
MRSAIAEGRPFYSFEYFPPKTEAGIENLYARIERMGRLEPAFVDVTWGAGGSTAELTFEL
ANTIENVLGLETMMHLTCTNMPRRRIAAVLDDCRALGIGNILALRGDPPRGRGAWSPIAD
GFSHASDLVRFIREEHGDHFGICVGGYPEGHPEAPSRERDLDHLAAKVETGADFVITQMF
YEPELYFRFLDDCRDRGIDCPIVPGLAPINGYQSFLRITGFGASAPPQIVSEIEARRYHD
ASVREYGQDLLTGICRRLLDGGAPGLHFYTLNLERSVQVILDRLGIVPERVERVLPWRSA
TAVGRPKENVRPIFWANRPKSYLARTRDWDEFPNGRWGDAGSPAFGDLGDHHLAFRPIKA
DMARERWGRELPSIDQVREVFAGFCRGDVDGIPWYDWPLDLESEPLRNALVRLNLAGLLT
INSQPRVNGAPSDDPAVGWGGAGGRVYQKAYLEFFVAPEQVPPLLAALEANESLTYHAID
RSGTAYSNCDTVNAVTWGVFPGEEIRQPTIVDPRSFEVWKDEAFDLWLSSWAAVYDEGSE
SRRLLQRIHDTYFLVNVVDNDYVDGDLLAYLIEAAQADEPPSMTIVAPVT
>A0A828G0E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPSGSGKPEMYASDLVELLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A523K3D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSDRYTQATETHLPVFSFEFFPPRTEAGFASLYRTVQDLKLLDPDFVSVTWGAGGSTRQK
TVEIVVRIQQEIGLTAMAHLSCIGSTPDQITKTLGQLTAGGIENILALGGDHPPEYEPPP
GAFTYANELASFIRTQSDFCLGGACYPETHPLAPDSETDLRNLKRKVDAGVDFLITQLYF
DNADFFAFEKKAREIGIDVPIVPGIMPILSAKSIRRMTSLSGAGIPNELQAKLTEVENDD
AATCDVGVEWATLQCRELLDKGAPGIHFYTLNKSMATRAIFEKLRKG
>A0A496YUQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKEVKTPSKLEKILNAGHLAVTSECGPPRGSDPNVIINKAKMVKDHVDAINITDNQTSVT
RLCSIASCIHLKLMGLEPVLQMVTRDRNRIAIQSDILGAASFDINNILCISGDHQKFGDN
PKGQNVFDLDSMQLIQTVRYMRDEGKFLGGDDIDRPPRMFVGAAANPFADPFEIRVPRLA
KKIAAGAEFIQTQCIYNVEKFKLWMKLARDRGLHKKVYILAGVTPLKSAGMAKYMRNRVP
GMDVPEQVVKRMSGVPKDKQPEEGLEICIETIQQLKEEEGVAGFHIMAIEWEEKVPEIVE
KSGLYPRPRIN
>A0A534XXB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIDDLLRFGSERGEPLFSFEFFPPKTEAGVEALFEAVRALRPLGPSFVSVTWGAGGSTR
GRTLEMVTRIKQELEIEAMAHVTCVGATRDELSQAIEEILDAGIDNVLALRGDPPRGQPS
FVPVDGGLKYASELVRLVREVAERKKKPVCVGAACYPEGHVETRDLMKDLRNLIEKVHAG
ADFLITQLFFDNRCYFDFVGRARAAGVEVPIIPGIMPIQNIEQVQRFTAMCGAHVPGKLA
AAMKVRKDDLDAAIQLGVAYATLQCADLLRRGVPGVHFYTLNRSPATRAILATLRAAEPW
LEATG
>A0A3L7YBP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRSGSRLEKALRAGRFAVTAELNPPDSADPQAVYDRAIVLASVCDGINATDASGANVHMS
SVGVCALLTRAGYEPVLQVSCRDKNRIAIQGDLLGAAAMGVRNVLCLTGDGVGTGDHPEA
KPVFDIDSMQLLRMARMLRDEARFLSGRKLDAAPRLFLGAASNPFVPPYDYRALHLGKKV
EAGADFVQTQFCFDVPRLRQFMATVRSLGLHQKVFILAGVGPLRSAKAAEWMRTHVPGVV
IPDEIITRLRQAAPGKQAAEGKRLCIEIIQQVREIEGISGVHVMAYRQEELVAEIIEEAG
LLPAPTRSRRAAAPAAVRPRTAKPKLSQSTSQQQEHPN
>A0A376HRI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPLGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A535TUA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSPSRLAGLLREGRFVVTAELSSSNSADPEATWRRAEVLRGSVDAINCTDNTGAHVHIS
SLAAAHLLVEKGLEPIMQLTVRDRNRLALQADLLGAAALGVRNLVLMSGDDVTAGDHPDA
RRIYDIDSMQLLEVAASMRDRGTYLSGRKLEQAPSFFIGAVENPFAPPLEFRPLRLQKKV
RAGAEFIQTQLVFDVPVFKRFMDMVGDLDPQRKVFIIPSIGIPRSARGARFMQQKVPGLH
VPESLVTRLERTAPARQAEEGIRIAVELVNAVREIPGIAGVHLIGIKWEEGVVQVAERAG
LLPRPTVSPVATVGGRP
>A0A7Z9TXV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHMRKILERDKTVFGFEFFPPRTDREWDALTDRMQTFEALEPSIVSVTYGAGGSTRTKTH
ALVCHIAENTSLDPIPHITCVGHSKEEITTILQSYADAGIDNILSLRGDTPKNGIENSDF
EHAADLVSFIREFPGASFGIGVAGFPEGHPETPNRLLQMEHLKAKVDCGVDWICSQLFFD
NASFYDWIERCELAGITTPTFAGIMPITSIAGMRRMAELAGGANFPAKLQRRLYRFQEDA
DAVAKIGTSWAAEQCADLLDNQVRGIHFFTMNKSTATEDIYSSLGVSSGSKLRNSH
>A0A5F2BMG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira yasudae|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDVKLMETVKELSRLNPDFVTVTYGAGGSTRDK
TVQILSEISKNYSVPTVSHFTCVGANRDQIRETLKGIRSAGIVNLMALRGDPPKGEGEFK
KTEGGFANATELISFIRSEKMDFCIGGGCYPEKHPNAKTLEEDVRNLKLKVEAGTDFLVS
QLFFVNSIFENFLNLVRKVGITIPVIPGIMPITSFSQIERFRSLAGCEFPPSLIEDLQEV
EHRPEEFYRRSLNFTVKQCRELLAMGAPGIHLYTLNQSHASYDIVRELKG
>A0A125FXY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia ubonensis|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTGLCQRLLDAGVPGLHFYTLNSAAATKTICERLGV
>A0A102M068|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia ubonensis|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTGLCQRLLDAGVPGLHFYTLNSAAATKTICERLGV
>A0A352CLS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MGSIRDKYVSGKTLFSCEVFPPKKDQIIEPTLQKLKEFRDISPDFLSVTYGAGGSNAGHA
VEVASFIRKEIGVDVLSHITSVGFSREKLAAGLDVFRDNGIENVLALRGDRPKYMSDEEY
DSRDFEHASDMASYISEHHPEFTIAGACYPDKHFEAESYEEDILNLKKKTEAGCSFLISQ
LFFDNDKFYSMLERMKHTGINVPVSAGIMPVTSAKMLGTTVTLSGTSVPKALSDLIARYG
EDDEAMKKAGIEYAIGQIRDLLDHGVNGIHVYAMNKPDIARQIFEAVR
>A0A1U8BLL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nelumbo nucifera|TrEMBL
MKVIEKIRTGTEEGRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPAFCDITWGAGGSTA
DLTLEIANKMQNMVCVETMMHLTCTNMPVEKINHALDTIKANGIQNVLALRGDPPHGQSR
FIQIEGGFACAFDLVNHIRENYGNYFGITVAGYPEGHPDVISENGTVGLEAYLNELAYLK
SKVDAGADLIITQLFYDTDIFLKFVSDCRQTGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPSEITAALEPIKDNDEAVRSYGVHLGTEMCKKIIANGINTLHLYTLNMEKSALAILRNL
GLIDDNRISRSLPWRRPTNIYRIKEDVRPIFWANRPKSYISRTIGWEQYPSGRWGDSHNA
SYGALTDYQFMRPRSRDKKLQEEWVVPLKSIEDINERFMKFCLGKLRSSPWSDLDGTQPE
TKVINEQLGNINSKGFLTINSQPAVNGEKSDSPVVGWGGPGGYVYQKAYVEFFCPRNKLE
AIIEKCKNFPSITYMAVNKEAQWMSNIGQDYVNAVTWGVFPAKQIVQPTVVDLESFMVWK
DEAFEIWNRGWACLFPENDPSRTLLENVQRSYFLVSLVDNDYVHGDLFAVFKDF
>A0A2S9M683|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia multivorans|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLDAAPHLSCIGSSRDSLRAILDQYRSCGIRHIVALRGDLPSGMGSVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATKAICERLDV
>A0A432QDZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp|TrEMBL
MKPDFRDYIQNHVVLGDGALGSYLFERGVERGRNLDLLNVQAPDVVFSAHEEYIRAGSQL
IETNTFGAGRFKLREAGIEGQVFAINRAGAEIAAKAAGHQVYVAGSVGPSGITFPFEEEE
ITLDDIRESFREQVRGLAEGGADLLIIETFSNLDEILLAIEVAKSEAPALPVVSQMVFPA
RARTVRGDDALTCAQQMRDAGADLVGTNCGRGIDAMVLAIEKMSPLAGEGVALSAFPNAG
MPEMVGHRMIYPAQPGYMATRAREMIRKGVHLIGGCCGTTPAHVQEFRSALRIKPVRVRG
AEVAVPGGVEEQVGGESRTGGFLTGLVPGRLPIIVELDPPTHLDVQPVLRGAKKLAQAGV
DAISLGENPLAILRTGNLGVASIIRNRFGVQTIIHQTGRDINALGLQSRMMEAHLLGIEA
VLAVSGDSAAGTDQPGVSGVFDLRSNGLIRMLDGLNRGLNMAGRSVKEQTNFSIGAAFSF
RPANPGLQISRLEKKSALGARYAMTQPLFSRDEVEQMMERVAHLDMLIFPGIFPLISSRN
AEFLHNEVPGISVPDDLRKKLAEYEEVADQRKVALEYTARLIEDISAFADGLYLISPLNK
WDIVLDFVIQARNAGWKGSGRADKLCAA
>A0A357AT73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MEKRGILEVMMEDRGALSIREFLKKHRLVADGAMGTYYSTLKREGNLLSELDNDKDPEII
KTIHKNYIEAGANLIRINTFACYPDVLGVDEAESAKLCRNAVKIAKQAVIEAKNNAELLG
KEESPLEVERKEVFIAGDIGPCSVSNENAERDYKANIDIFIEEKLPVIIFETFTEEKEVL
SLAEYVKEKSPETFVIASFCINGNGTTGRGISLEQIVHHCLESKSIDAFGFNCGIGSSNM
YKVLLSANIKSFNKYFYVSPNAGYPEFLNSRMVFINNTSYYIDYMKQIASLGASIIGSCC
GTTPEYTRKISEFVRELPPVELAGEYKEKLEVSEILYASNEFDRKLCANKRVIVVELDPP
YYQDDEKMISRAKELMGYDIDMIDIADSPQGKSRVDSVLMSVKLQNMTSIPCMPHITCRD
RNMISVRSTMLGAYVNNIRNMLIVTGDPIPADIRSSATGVFDYNSEKMMQFLNEMNRAYF
SADPIVFGGAINQGRPNVDYEIKRIKKKMEAGARYFMTQPVYSDRDIEVLDRMKKETGAK
ILCGIMPLISYKNAFFVKNEIAGIVVPDEVLAMYSPDMNREEGEEAGRQISKEVIKKAEP
VVDGFYFMLPFNRINLLDGLVDKKKGMEL
>A0A357RMG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citreicella sp|TrEMBL
MTRPDISFEFFPPRNVEATFRLWDTVQALAPLKPRFVSVTYGAGGTTRELTRDVVAALHK
RSGLRVAAHLTCVDATREETLGIARQFQEAGVQDIVALRGDPPKGSSGFTAHPDGFASSL
DLIAALREAGDFTIRVGAYPDKHPEAADAQADVAWLKRKFEAGASEALTQFFFEPDSFFR
FRDACAAAGIDKPVVPGILPIENWKGARRFAEATGTKIPGWVIDLFESPQAEGRQDQIAT
ELCTRLCQDLMAGGVDKLHFYTLNRPELTRDVCAALGVTPETALENVA
>A0A0D9W0M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leersia perrieri|TrEMBL
MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDEALTTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVRHIKATYGDYFGITVAGYPEAHPDAIQGVEGATPEAYSSDLAYLK
QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILANGIKTLHLYTLNMEKSALGILMNL
GLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPLKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKVNLKGFLTINSQPSVNGERSDSPSVGWGGPGGYVYQKAYVEFFCSKEKLD
QLIEKSKAYPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWSRGWACLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAFKDI
>A0A2T9HYI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Agona|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1L3LN96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium americanum|TrEMBL
MSPDVNPFDPSAPLDALPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYDRAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHEATPTETLVAERLGHLREGIEENQQQMAEAAAH
HPH
>A0A4S2D038|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides caecimuris|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESAFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSNTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMVPKTFKVDLPEELVKEALKCKNDAEAEQVGIEWCVSQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A6J7GVM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVVRTSYSLEFFPPKDGEGEVRLWAALEALKPIAPEFVSVTYGAGGSTRNRTIGVTEEVT
HRTKIPTVAHLTCVGSSRQELISILHMYRSAGIRGVLALRGDPTGGPRAPWTPTSDGFTH
ADELVQLIHEFGGFDIGVAAFPDGHPSSEGDSVKDIDVLLRKEFLGASFATTQFFFEVSK
WEQLVYALAARGSSLPIIPGILPITNIKQLTRMAELGGTPIPPSISARFAAIDGDIQGTH
ELGIEIATQLCEDLLRAGAPSLHFYTMNSPTATLEIYGNLNHAH
>A0A1H4NYH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas frederiksbergensis|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARHLATYSPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A496QZM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MSGNYNMFHVEVLPPRQDAEDLEVRLERFATRYKRVLDAGYCACITDNAMGNMSFQGTEI
IEEYDLPVDAVNVMIHLNTFHSKNVLDDILKSCIDRGIKYLLVISGDGNVRFPKLRPADL
GIQGVSSVTAVELLQYINREYSGSFHNGVAFNPYEPEEEEHEKMMKKIDAGAEFVITQPI
IDSNPIVDKLISEIDIPVMVEAWMSKKLHLLSDCVGYDIPEDTEYDPIESLKNLQINYPS
GGVYLAMMNYKRQFNLLSEIGRA
>A0A6J6U708|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSPIRTAPSLGAVLAGGGHSFSFELFPPKTDAGEQALWQTVRELEALKPTFVSVTYGAGG
STQDRTVRITKQIAEHTTLLPVAHLTCVDASVEDLRRVIAQYSDAGVNTIMALRGDPIAG
PESRWVQHPGGLQHADELVALVRSLGAFSVGVAAFPEGHPESGDFEEDARVLAAKQDAGA
EFAITQFFFRAEDYERLVTRAAAHGCTMPIVPGLMPVTNVAQIERFAVLSGAQFPSELAD
KFGKIKDDQSAVHELGVEVAADLGGKLLAMGAPGLHFYTLNRSTSTREVYEALGLNEV
>A0A353A2A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotellaceae bacterium|TrEMBL
MSITEMIGSHQGTAFSFEVLPPLKGSGTAGLFHTIEQLREFDPLYINITSHRSEYVYREL
EGGLVQRQRVRRRPGTIAIAASIQHRYGIPVVPHVVCSGNCREDLEYMLIDLQFLGISDL
LVLRGDKAREESAFRPTGDGPAHATDLIEQVNRFNGGHFWDGTEMKCKGEPFHYGVACYP
EKHEEAANLEADLAVLKMKADLGAEYAVTQLFYDNEKYFSLVRRAREAGITIPIIPGIKP
LAKLSQLTMVPKTFHCDLPEALYQEAVKCRTDEDVRQLGIEWGVQQCRQLIGSGVPSLHF
YTVSAVPSIARIASQIY
>A0A3M3FX83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. glycinea|TrEMBL
DKSAPTKYVFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTY
GAGGSTRDRTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGD
LPSGMGMASGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANA
GADSAITQYFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWI
RKQLEAYGDDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A2B6UNQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDVAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>B0VZI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Culex quinquefasciatus|TrEMBL
MTGKSRNVLPAAAAPFNGSTAAAAVQCQGQAKASTTTKTVSVSLVGRSSFVSILSRGSVS
FGRLSFARNLSADVLVWWLSSSRDLLRTARGTRVTVEKRTEKRLRGLNLSSPSREKRRPP
PTSPMHRQTVESDPNGEEDKSTILAAAAVTAEVMHSHENSRNLKQVIQRWTTSERLCYSI
ELIPREDFHLDLGRLAPVFCSLPWISDNNLQYQRFADTPMLKMTAKIVPHCSAVPHLSCY
NITETQVDKFVDMGNWNLFVIRGDTVSEGQRFQHSCDLVEYLRAKNNPDLTIGVGGYPYG
HPESPSVDYDVKYLKQKVDLGVDFIVTQTLYDAASFLAYVDECRRAGITVPIVPGLFLPG
SPDQLETVLALTRVNPPAGVRELLQSHAHDEPDQFEAFVVKHFAELIRTLRRERPDEVRL
VHFFTFNRLDLLKKVLDAIADLL
>A0A442J339|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDDMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIREFADFGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLIERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A174GBE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides uniformis|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A3V9NQP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella gallinarum|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3S3KBE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAKRLDHILHDEITETQVDMVK
TAH
>A0A2I4G605|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Juglans regia|TrEMBL
MKVIEKIQEGLGDDGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPTFCDITWGAGGST
ADLTLDIANRMQNIICVETMMHLTCTNMPVEKIDHALATIKSKGLQNVLALRGDPPHGQG
KFVQIEGGFACALDLVKHIRATYGDYFGITVAGYPEAHPDAIGSDGLATEEAYQNDLAYL
KRKVDAGADLIVTQLFYDTDNFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
RIPAEITAALEPIKDNEEAVRSYGVHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMN
LGLLEETKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYITRTIGWDQYPHGRWGDSRN
PSYGALADYQFMRPRARDKKLHDEWATPLSNIEDIHEKFKKFCLGKLRSSPWSELDGLQP
ETRIINEQLGKINTKGFLTINSQPAVNGEKSSSPSVGWGGPGGYVYQKAYVEFFCSREKL
DALVGKCKDFPSLTYMAVNKEGSWISNSGQTDVNAVTWGVFPAKEIIQPTVVDPTSFMVW
KDEAFEIWSRGWAGLYPEGDASRKLLEEVQSSYFLVSLVDNDYIHGDLFAVFADF
>A0A2E4THH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actibacterium sp|TrEMBL
MTADQSQTRPDAPRVSFEFFPPKTLQASFRLWDTVQALAPLNPEFVSVTYGAGGTTRKLT
HEAVDAIHKNSGLTVAAHLTCVEATREETLEIARSYLDAGVRDIVALRGDPPKGQGSFTP
HPDGFADSCELIAALKETGDFRIRVGAYPDTHPEAADADADVAWLKRKIDAGADAAITQF
FFESDAFFRFRDRCDKAGITAPILPGILPIENWTSARRFAASCGTVIPTWMDEAFETAAA
NGSEDETATRIATEMCETLRAGGVDDLHFYTLNRPTLTRDICLALGVEATPDTLGRVA
>A0A178TY22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parageobacillus thermoglucosidasius|TrEMBL
MGLLQDLKERILIADGAMGTLLYSHGVDRCFEELNLSKPEDILHIHEAYIAAGAEVIQTN
TYGANYVKLARYGLEDEVPSINRAAVRLAKQAAKHKAYVLGTIGGLRSINKSAVSIDEIK
RTFREQLFVLLNEDIDGLLLETYYDLEELKTVLAIARKETDKPIIAHVSLHEVGVLQDGT
PLAEALAQLEQLGADVVGLNCRLGPYYMIRSLEEVPLPDHAFLSAYPNASLPDYRDGRLV
YETNTDYFKETALAFREQGVRLIGGCCGTTPKHIEAMANALVNRTPITEKAVKQRHVSIS
IQTNEPNAAPPLQDIVRERRSVIVELDPPKKLGIGKFLEGAKALKAANIDALTLADNSLA
TPRISNVALGTIIKEQLGVRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVER
LEKKIQCGAHYFITQPLYSEQKIEEVYEATKHLQTPIYIGIMPLVSARNADFLHHEVPGI
TLSDEIRARMAACANDPVQSAREGIAIAKSLIDAAFELFNGIYLITPFLRYEMTVELVRY
IHEKEQAAQEREVLHG
>A0A1H0QBM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas reinekei|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETADHFHIEVAAYPEMHPQARNFEDDIANFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A8D5Y995|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. 19-13652|TrEMBL
MGLSEKIRANQAGILLYGMTPPKSTNEPARIDEIAKRALVRIKNAPIDGIVLYDLQDESA
RNSEERTFEFIKTISPQEYYRKYFALETDAVIYQAVGQYDKEELEGFFDTISSRESVVLV
GASSKNSRVKTRLGEAYDIYRKSGAKSALGGICIPERHTLKHDEHLKVAAKVAAGCRFFI
SQAVYDLAAAKKFIDDYASLGCERVPLIFTFTPCGSERTLEFMRWLGICVPDFLANRLKN
SDDMLSASCELCLEMFKFLFVYGRLKGISVGANVESVSTRLVEIEAANELLKNIAAYLGR
>A0A1D2R104|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon WOR_SM1_SCG|TrEMBL
MNKFKTKLKNNDFVKIIELIPPKDSNITPAINDLKAVQDKFDIVSVVDNPRGIVHLSSLA
CSCLIRKEGFETIMHISCTNKNRIEIQSQVLGAKALGIKNLLFVTGDHVLSGDNREARPV
YDIDSVLAIRLAEKLNKNNKSGSNLFIGASANHLSGEPQFKSLGKKAEAGAEFIMTQPVY
DIEKFKNFIEKIKIDIKLYFIAGVMPLKSVKHAEFINNKIPGIMVPEKLIVRLKNSKNAH
LEGINIANETILEIEKIKEISGINVMGMFDLKTIT
>A0A7Y3GBU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MRIVECFGQDRPVISFEFFPPKTDKGFDSLYRTARELKRLEPSFVSVTYGAGGSTRRKTV
DIVSRIQREIGITAMAHLTCVCASEDELVAVLDRLEGEGIQNVLALSGDAPADRPDHDRA
DDAFRWASELAAFIRSRWGFCLAGGCYPEVHPDAPDAETDLRNLKQKVDAGVELLVTQLF
FDNADYFDFVERARAIGIEVPIVPGIMPVVSTQNIRRIAKLSQARIPEALDRELSRVEGD
DPRTLEVGIEWATLQCRELLAGGAPGIHFYTLNRSPATRRIHESLFGAS
>A0A1D2QUA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon WOR_SM1_SCG|TrEMBL
MSLLRDNFGKKFIATGEASPPPGPDMTEFAHEVAEMKPMMDKIEGVNVVDIPGARVLMSS
LGASIYMMQQGVEPIFQMTVRDRNMLALQADLISAATFGIENVLSLAGDHPACDAADHKG
AKPVYDLDSTTLITTMKMMNDGKMLNGSDMNGKTNFFMGAAIGPTSSPLDGEVYKTKRKL
NAGADFFQTQGIFDVEPMQNFLNLYDKLIGEDIASKTLVGIVPIRSYGMMMYLLSMPGVV
IKDAVVNSVKKAQDEQKKTGKKGIIEDAGIDLCINLVDDIKGLGMKGVHIMPVGNVRALK
AIVGSL
>A0A8B9K6F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Astyanax mexicanus|TrEMBL
MVNQRLDTGWQPCKSDSSGGSNSGESSKESSRCSTPVLDTDRTDRLRDKMRRRIESGDHW
FSLEFFPPRTAGGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESILHLTCCKQTKEIITAHLNKAKRLGLKNIMALRGDPIGADWEEEEGGFNYATDLV
KHIRHEFDDYFDICVAGYPTGHPEAESYEDDLKHLKEKVDAGAHFIVTQLFFRAETFLKF
VKDCRAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGI
QQAVEMCRVLLASGDVSGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSSKEALLK
MWEEELTSEDSVYQVFTNYITAEPNKSGHKVMCLPWNDDPLAPETNMLKEELEKVNRRGV
LTINSQPNINGKPSSDPVVGWGPPGGYVFQKSYLEFFTSSENVNALLKVLKKYEPRVNYH
IVNVKGKNITNAHDMQPNAVTWGIFPGKEIVQPTVVDPVSFMYWKDEAFALWIEQWGKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIDDMFELLDAPPEPLDQENLQ
>A0A8J7M1H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomesophilobacter sediminis|TrEMBL
MKIADLMSRGEQFVSLEFFPPKEKTEWPAFFAVAERLSRLNPLFASVTYGAGGSTRGDTL
EIVTRLKKDYGLETMAHLTCVGSDPNELERFLAELSGAGVHNVLALRGDLPQDTPQLPEC
RPLRHASDLVSFIRAAHPEIGLGVAGYPETHPEAVSPESDLDYLKLKLDLGGEFAITQLF
FENQRYFDFVARARKIGVIKPIIPGILPVVSLKVIRRIVSLCGSDLPPAYLAELEAADAR
GGAAAVQKLGIAYARRQVQELLAAGVPGVHIYTLNRDEAILELVDGLLPAATA
>A0A1J4E6D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. HMSC067F07|TrEMBL
MSQFLNQLQNNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGANVIQT
NTYGANFEKLKTFGLEHRVKEIHKAAVQIAKRAAHHDTFILGTVGGFRGVRQDDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELKSIVVATRRKYEIPIIAQLTASNTNYLVDG
TEINDALKQLVACGANVVGLNCHHGPHHMQRSFSHIELPDNAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIRYIKTAVQGLTPIKDKKVVPITKKS
NHKPTKVVKQNLTSKVKNGPTVIVELDTPKHLDTDTFFENVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQQYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A5C3EZF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudozyma flocculosa|TrEMBL
MSPAPSASTSASASASTSTSSQPSMTQHPSHVTTRIARSVAADRPFWSFEFFPPKTTQGL
ANLYSRVARMRSNLDPAWINVTWGAGGTTTARSLELAARVQKGHLHPDLDRVRGEANDVE
QGQAGFTRVNGGDADTAVGQDACDVCLHLTCTNVEKEALDATLQKAKELGVRNILALRGD
PPRGQEYWVAADSRFQHAIDLVRYIRQEHGDFFCIGVAGYPEGHADYVDRDVQRDIRHLK
AKQDAGAQFVITQLFYDVDQFLAWYRDCRAAGITIPILPGIMPVQNYLSFRRMTNLCKAK
VPQPVLDALEPIKSDDAAVKEYGVSLSIHMIARIYLESDIRGFHLCTLNLEKSVERVLEG
LGWQADRGAEADDLSGPTAALAADGDASAPPPHKHLEATRNQMLSDRTGHNTPRDLKLTT
AEALRRTLARTSSSYQVPETSTWDEFPNGRYGDSRSPAYGEMDGYGVSLKVPPQDALRIW
GHPVAHADISRIFAAYLEERIACIPWCDAPLMAETVRIRPHLLQLNLAPQNCPHNGECKG
WWSVGSQPAVDGAPSTDPTFGFGPKGGYVFQKAFVEVFMSTKDKDALVAKIEGEGRGEVS
YFAGNRRGAFQSNLGEGEVNTVTWAIFPGKEIVQSTIIEKESFEAWREEAFAIWSEWELL
FPPASATRQLLRNIGEERWLVTVVHHDYKDVDALWNFLGCST
>A0A2E9VP88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubinisphaera sp|TrEMBL
MNRLPDLLKSDSPLISIEIFPPKTEKGDELLYETLDTLSKFEPKFISCTYGAGGTTQTRT
LELCQHIQKTYEIPATAHFTCVGSSRDELIAWLDKAAAAGIQNIMALRGDAPKGETSFKA
VEGGLSYANELVSLIRERHPEMGIGVAAYPEKHAECIDADLDLTNLKRKIDAGADAAFTQ
LFFDNDLFFAFRDRYEKAGCAIPLIPGIMPITEFSRIKRITEMCGTAFPAELSARLENVQ
EDPDAQLEIGIEFAISQCRELLENNVPGIHFYALNKSQACQRILEALKTA
>A0A1I1GTY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas sp. OK412|TrEMBL
MSQKNAQKNFSIEFFPPKTPEGAEKLRVTRAKLAELHPRYFSVTFGAGGSTQKGTLDTVL
DIRSEGHEAAPHLSCLGSSRESLRAILAQYKDHGIKRLVALRGDLPSGYGAMDISSGEFR
YANELVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDVQRFVSKVKAGANGAITQYFYNA
DAYFRFVDEAQKLGAAVPVVAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTDS
IRAFGLDVVTQLCERLLAGGAPGLHFYTLNQSPATIAIWQRLKL
>A0A0S8I6N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium SM23_61|TrEMBL
MGFQESLAAGKFVITSEIGPPKGTHIQEMMADAELLRGRVDAINVTDLQSSVMRLGSLAV
CHLLQEKGLEPIFQVTCRDRNRLALQADLLSASVLGIRNVLALTGDYASLGDHPQSKPVF
DLDSVNLLKVIRTLEGGTDMVGNALQGAPRFFPGAVVNPGGNPVEAQIIKMEKKIKAGAN
FFQTQAVYDVGAFEKFMKRVTPFRVPVLAGIILLKSAGMARFMNKNVAGVFVPEPLIQKM
AKAGDRVKTSIEIGAELIQDLKGMCQGVHIMPIGWESKVPALLDATKL
>A0A5C5G3P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodotorula diobovata|TrEMBL
MSGTSTPELRQHQSQRVSDRIAQLSPDQPFYTFEVFPPKTDIGLANLVDRIDRMSSLSPT
WMHVTWGAGGSTQARSLELAGASQGMGLETCLHLTCTNLEEGVLEKTLKRAKELGVVNLL
ALRGDPPRGEEYWTASSDKFQHATDLVRFIRNEYGDAFCIGVAGYPEGHADSPDKLADIE
FLFEKQQAGADFVVTQLFYDVDVFMDWYRACRKRGITIPILPGIMPIQNYQSFRRMTNLC
GTHIPDDIMSDLERIQHDDAAVKDYGVRLSVKMMRALFEQGIRGFHLCTLNLEKSVTRVL
ELLQWVEPDATRAKPRLQRTLAPNGAPLPKVVNSLRPRTDSSQSVAGPDIARKDSPASWD
EFPNGRFGDARSPAYGEMDGYGVSLKLPPGEAMRLWGEPTSPADISRVFSSYLRETIPSN
PWSEEPLRAETASISAHLIEMNDSRHWWTVGSQPAVDGAPSADPVHGFGPKGGYVYQKAF
VEFFLTGAELDELERKSAEDAKRRQESGEGDDALVTWFAGNARGDHRSNMSKGDVNAVTW
GVFGAKEIVTTTLIEEMSFRAWCEEAFALWREWSLLYAAASPARAFIRDVAETRWLVSVV
HHDYKDRDGLWKWLLALKTTPSQEQA
>A0A0S8IDR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium SM23_61|TrEMBL
MAQRFREVLKSGAFVVTSEIGPPKGCELSKMIHHIGLLKDRVHALNVTDNQSSVMRFPSL
GGAILVKENGGEPILQMTCRDRNRMALQSDLLFASTRGIRNVLCLTGDAITVGDHKTAKS
VFDLDSAQLLKAIRLLESGKDMGGNALDGGVEFCAGAIVTPEARPLEPQLMKFEKKVECG
AEFFQTQAIYDLENFRRFMDYARRFPAKILAGIVLLTSARMAKYMAENVPGIFVPPSLIE
ELAGAPKGQALAKGIEIAGRMIRTLREEKICDGVHIMAIGREEVVPQILQEGGLGAPA
>A0A418Q7H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium falsenii|TrEMBL
MTGMNRQIAVSQTLALNTPGRVPFSVEFMPPRDDAAEERLWNAAEAFHDLGVSFASVTYG
AGGGTRERTLRVAERLATKPLTALVHMTLVNHTTEELQDMLRGYAERGLTNLLALRGDPP
GDPNAPWVKTEGGLEYAKELIELVREMPECENFDIGIASFPEGHYRAPDLDADTAFTLEK
LRAGAQYSITQMFFDIDHYLRLRDRLARADREHGSKPIIPGLMPITSLRSVRRQMELAGA
SLPSDLERRLLDAANGDEVKNKDAIREVGIEVTTEMAERLIAEGAPDLHFMTMNNVRATQ
EVLHNLGMAPAWGPDLGHDMVR
>A0A431MAH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobiaceae bacterium|TrEMBL
MTDSQASADKRPAISFEFFPPKTEEMEKNLWTVIEKLAPLSPNFVSVTYGAGGSTRERTH
STIARILTETSLIPAAHLTCVDASRASVDEVIGGYHDVGVRHIVALRGDPPGGIGTPYAA
HPEGYQTSAELVGAIRHRYPDMEVTVSAYPEKHPQSPSFEADIDMLKAKVDAGATRAITQ
FFFDNDLYLDYLDRVRAAGITIPIVPGILPVQNFKQARNFAERAGASLPDWLAEKFEGLD
DDPETRKLVAAAVAAEQVQALTEQGVKNFHFYTMNRADLVFAISHLLGIRPNGAQKAA
>A0A2K1NJT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrotoga sp. HWHPT.55.6.3|TrEMBL
MKIVDLIKQSNKPVLSFEIIPPNVGESIDSIFNVVDNLIEFYPKFINVTKHANEIEYVEE
NGKIMKIIQKKRPGTVGVSASIKHRYNIEVVPHLICTGFNKYQLEDILIDLNYLRIENIF
VVRGDKKRYTWKETDEYEHASQLVEQIANMNRGIYTFPTKEHNSTNFCVGVAGYPEKHFE
SPNFEKDLDYLKLKVDMGATFIITQMFFDIEYYKNFVNKVRDLGIEVPIIAGIKPLGSKK
TLYNIPKTFHVNIPKSIVEEFEDAKSSQDEYIIGVRHAIKLIEQLLELGVPGVHLFTMGK
GKIVKDVLSAFKGIF
>A0A0F8UM75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus rambellii|TrEMBL
MEKITDKIAALPPGANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
ASRSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCVGVAAYPEGHPADSFQEVQDPEVDLPWL
VEKTQAGADFIMTQLTYDIDAYTRFETMLRNHESGAFKTIPIIPGLMPIHSHKILTRVTK
LSHVKIPPPILAKLEEVRYDDDAVKRIGVDIIAEIVDGVRKLVCPGLRGFHFYTLNLEKT
VSFIIERCNLIPDYPEDSEAVDVSEELSALTVDGSQASTLARRRRASSVGSIPHNRVIVD
RVTETSSKGSVTHETPAASAGMPALPPDRNTTLQISEGLGALGREATWDDFPNGRWGDAR
SPAFGEIDGYGPSLHVAPAVAHRIWGYPVTYDDISNLFRRHVSGDLYMVPWSEGGAEENS
SGLNAETETIRPELLQLIDNKGWWTLASQPAVNGVRSDDPIYGWGPPGEGFVFQKPFVEF
FCPTKDFQTVLKPVLKQHGHEKLAWFAANSKGEFETSLPAQSAEADPIEMNPANVNAVTW
GVFRGKEIITPTIIEEVSFRAWGDEAYRIWDEWRRIYPRNSPTERFLDKTRDDVWLVCVV
GQDFGAGTEIGSQEEQDEKKWMWNVLANC
>A0A7T0WEV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. A40-4|TrEMBL
MSRHEHPLGISFEFFPPGTDAGRDKLIQTRDELAARNPRFFSVTYGAGGSTQARTREIVR
KVSQSGVTTAPHLSCIGSEKAQLRDLLTQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRDETGDHFDIAVAAYPESHPQAPNLDRDVENFARKMKAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIADF
GTDVVSRLCQRLLDGGAPGLHFYTLNQSKPVLKVVDNLSG
>A0A1I0DWB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. NFR01|TrEMBL
MKPDLRSAWSNNVLVGDGAMGTFLYQKGFPVGISYEELNLISPGVIEDVHRSYIEAGAVL
LESNTFSANYDKLSKYGLESKVEEINRAGMRIARSAAGENGYVVGAVGSIRAGKRANLSS
SELKKYFAEQLSALLLEAPDGILLETFYDVEELHLAVKAVRKLSDLPLICQLAVDETART
LDGLTLPEAFRVLEQDGADVIGFNCRTGPNGIKRALGTLSGSLTLPASVFPNAGVADYVD
GQYRYGASPEYFGQMAPVFADMGARIIGGCCGTTPQHIAEISAALKDYIVKPLPEPQTEA
IQRITVQEHLAEDGGEEGAEPTLVDLVKQRHTVIVELDPPRDLDITKFMRGAEALRKAGA
DALTLADNSLAVTRMSNMALGHLVQAKTGLRPLVHIACRDRNLIGTQSHLMGFDALGIDH
VLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIRQLNDGIAFSGKPLKQKAKFVIGAAFNP
NVKHLDKAVERLEKKINSGADYIMTQPVYDPELIARIAAATKHLSVPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRGRMSGLEGEAGRAEGVKIAKELLDAATAHFNGIYLMTPFMFY
EMSVQLLEHIWTKQGRKLSPLFR
>A0A6M7U2L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium loti|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILNETNLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A7V5FUA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKTTDPFAESLNNPKSFTLTYELVPGQGAGGKKVDRLLEFARRAREDGRITALSVTDNAG
GHPALAPIAIGAEIQKIGLEPLIHFSLKDKNRNQIESHLFLYQRQKFRHLLVLGGDFPKP
TYYGQAKPVYDLDTIQTIALVELIKTGHYRQMKEDEICNHPFDFQCGCVVSPFKMTEAEQ
VWQYANLLKKIRAGAQFIITQLGYDLSKYENLIRFLRQEHITIPVLANVFIPSPAVAKFM
ARGGVPGVILPKKMAELMQNEDKKQRLLRAAGMIAVLRDIGFSGIHLGGNGLSFDDVRFV
LDKAEQIQGADLQSARENAHFPIRGIWSLYKNNTGRQQKPHPGAKPGCRPLHHLMHRLLF
SRTNPVSRAFGRFCRFCDQYHTTRLMLTGCEKIIKGLLFGCRMCGDCTLSENTYLCPQSG
CPKKLVNGPCGGSR
>H1LIV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus kisonensis F0435|TrEMBL
MSLTALFKQKTVFSLEVFPPKKTSPTAAILPTLEQLQSINPDFISVTLGAGGTDHYNGTV
SVADLIQNQLHIPAVAHVPGLYQTKQQVLDLLDKLSSINIENVLALRGDRIPDKQPAGDF
NHANELVAFIKQNRPNFSIASACYPNCHTEAVDFVDDIGNLKRKVDAGVDHLITQLFFDN
QAFYDFKEKTEIAGINVPIEAGIMPCTNRNQIARITQISGVPLPKKFRAIMDRYQDNKEA
MRDAGIAFAVDQIIDLVSQGVDGIHLYSMNHAGIARQIWEETHSVIEA
>A0A1G8U097|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea jiangxiensis|TrEMBL
MSFELICEIEPPTKPDLKHVRHQIGTMSKIAHSFLIPDNHIGRATVSSVAVAHEVESMGG
RGIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTSGNRTSDLTVRSMIEEARKF
SPDFRLGAAAGLRPLPAWKRAADFLFAQVSFSVEAQLRWREANPVDVPVYAGVMVLASER
HARMLAAAIPDIALPEELIEKVAADRMAGVEAACEQVLALRDSGAFAGVHLIPVSRYRDV
ESRLATALL
>A0A3M4YLV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. striafaciens|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A126QNA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio indicus|TrEMBL
MRVCDLIQRKSPFLSLEFFPPKEREAWPAFFAVVDKLKVLDPLFASVTYGAGGGTQDNTL
EIATRMKRDHGIEPVTHLTSVGASAEKLDAFLDSLRAADIQNVLALRGDPPRGVADFDFN
AQEFKHASDVIEHITARYPEMCVGGAAYPEPHCESPSIKSDLDMVLLKVKKGAQFLVTQL
FFDNRLYFDYVDRLKAMGSDVPVIPGILPIMSLKSAKFTLSLCGAAIPGKFLSALEKAYE
EGGDDAVYALGIDYATKQAQQLIDGGAPGVHLYTLNRAEAVLEIGKNLNI
>A0A1M5VIX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseolinea serpens|TrEMBL
MKVTEHIANANGKTLFTIEILPPLKGENIKNLFKNIDPLMEFKPPFIDVTYHREEYVYKK
KENGLLEKRSTRKRPGTVGICAAIQNHYKVDTVPHIICGGFSREETENALIDLDFLGIDN
VLVLQGDPIKTEPRFVPDPDGYMYASELLQQVVKMNQGIYLDDELLHAAPTDFCIGVAGY
PEKHYMAPNLKNDLKYLKLKVDLGAKYVVTQMFFDNEKYFAFVDKCREAGINVPIIPGIK
PLATKSQLNILSKTFHIDIPEALADAVEDCKDNQAVKEIGIEWTVQQSKELIKKGVPTLH
FYTMGKSDPIYRIAKELF
>A0A2N5AVP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium loti|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVKRLEPLRPNFVSVTYGAGGSTR
ERTARTVRRILNETSIPAAAHLTCVGATREEVDAVIRDYFATGIKRFVALRGDPASGVGQ
AYTPHPGGYQNGAELVGGLKAIADFDISVAAYPEKHPESPDFATDIEMLKRKVDNGAKRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHNFRQVANFASRAGAHVPAWLAERFE
GLDNDPQTHMLVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRAHQSAPE
ESQSKTGSAAA
>A0A326QFJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp|TrEMBL
MGAGCFPVVVLLQRAIARGAFAVTAEVMPPRGGDPSRTLAMARLLKGRVHAVNVTDGSRA
VMRMSSLALCRLLLDAGLEPVLQLACRDRNRIALQAELLGAHALGIRNLLCLTGDPVRAG
DQPNARPVNELEAVRLLQQVSDFNAGRDPLGGSLPDGPTALFAGAAADPQSPSWSGLRRR
LSRKQAAGAKFLQTQMVMEASVLRRFCEEIAAPLGLPVLAGVFLLKSARNAEFINRVVPG
ASIPQHVIERLAAAADPASEGIRIAAEQVTSFREIAQGVHLMAVKAEERIPNILSLAGIE
AIDPLTACPSA
>D1CWA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella sp. 83/13|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A671QEQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus anshuiensis|TrEMBL
VGGSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHWFSLEFFPP
RTASGAVNLISRFDRMGSGGPLFIDVTWHPSGDPGSDKETSSMMIASTAVNYCGLESVLH
LTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLVKHIRCEFD
DYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAETFLRFVKDCRAIG
ITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGIQQAVEMCK
VLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKVEDVRPIFW
ASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEELMN
EGSVYEVFTNYITGQTNPSGHKVMCLPWNDDALAPETNLLKDELEKVNRRGILTINSQPN
INGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVQGKN
ITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWVKLYEDESPSRM
IIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFALLDSPRATQEEGSQS
>A0A671KK56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus anshuiensis|TrEMBL
MVNQRADVGWRSSKSDSSGVSNSGESSKESSRCSTPVLDTDRLQDKMKRRIESGDHWFSL
EFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVNYCGL
ESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLVKHI
RCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDSGAHFIVTQLFFRAETFLKFVKD
CRAVGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRSYGIQQA
VEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKVEDV
RPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWG
EELMNEESVYEVFTNYITAQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGVLTI
NSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVN
VQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDE
SPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFALLDSPRETQEGSQS
>A0A1M5HJV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus nigrescens|TrEMBL
MKRSLAVRDTTTRATLRHAFQGLGYEVIPFKKTEQSVLAHVPKDVRLTVTASPAKGQDAT
IDLAVALAAHGYSVAPHLSARQVRDRAHLADVVDRCREAGITDVFVVGGDPTEDPTEFRH
AHDLLVALHELDHGFTDIGIGGHPEGHPSAAEDVMFQALVDKAPLATHIVTQIVFDPAAI
LRWARELRTRGIDLPVHVGVPGAVHRQKLIRVSGGLGIGESAKFLKKQQNLLWRFFVPGG
YSPDKIIKGLAPHIGKPDNAIEGFHVFTFNDLEPTEAWRRRTLADLA
>A0A6S6ZXU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter deleyi|TrEMBL
MHPSTPKSLRHITDGYSLEVSTKDIAALTAAAPRILPGSTISIPYLPGQDDQARLAAARA
VRALGFEPMPHLSARRIASLAELDAFVTRAVAEAGVERCFVIAGDPSTPVGPFADSASLI
ETGVFERAGVRVVGVGGHPEGHPVMSASDRWEVLERKCQMIASRGMAPLIITQFGFDADV
ALAWLQTLRERGIGHPVRVGVPGPAGIAVLARYAALCGVSACASMWSKYGISLGKLFGTA
GPDVFVDRLTAGLTDAHGPVSLHFFPFGGIAQSVKWIEQYRARTPALDRAGPAVS
>A0A7J8F9Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Molossus molossus|TrEMBL
MTIASTAVHYCGLETMLHMTCCCQSQEEITGHLRKAKQLGLKNILALRGDPLGDHWEEEE
GGFHYAVDLVKHIRKEFGDYFDICVAGYPAGHPDAESFAADLKYLKEKVLAGADFIITQL
FFEADTFFRFLKACSEIGITCPILPGIFPIQLVKLSKLEVPQRIKDVIEPIKGDDEAICN
YGIELAVGLCRELLASGLVPGLHFYTLNRRMATTEVLKRLGMWAEGPRRPLPWAVSAHPK
RWEESVRPIFWASRPKSYIYRTQEWDEFPSGRWGSSSSPAFGELKDYHLFYLRSKAPRGQ
LLKMWGEELTSEESVFDVFVHYLSGEPNQNGCRVTCLPWNDEPLAAETSLMKEELLRANR
RGILTINSQPNVNGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRKTVEALLQVLKKYESRV
TYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFTLWAEQWG
KLYDEESPSRMIIQDIHDNYFLINLVDNEFPLDNCLWQVVEDTFELLNRPTSQ
>A0A671QC16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus anshuiensis|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPSGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAETFLRF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDALAPETNLLKDELEKVNRRGI
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKACGVSAVYDLHWLVS
ISTTPANKKKIIIIINLYTVVCVG
>A0A0L8AJI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivirga seohaensis subsp. aquiponti|TrEMBL
MKVTQHIKRAKGKTLFSFEILPPRKGENVNGIFDAIDPLMEFNPPFIDVTYHREEYIYKQ
HDNGLLEKVTTRKRPGTVGICAAIMNKYGVDAVPHIICGGFNKEETENALIDLDFLGIDN
VLVLRGDAIKSEGRFVPDPDGHSYATELMQQVLDLNQGKYLHEEVEMAKTNFSIGVAGYP
EKHFEAPSLKSDMKYLKQKVDMGAEYIVTQMFFDNQKYFDFVEKCRKADIHVPIIPGLKP
LTTLNHSTILPSIFHVDLPDDLVDELDKCKDNKAAREVGIEWCIQQSKELMEAKVPCLHY
YTMSKSSVIKQIAEKLF
>Q0AZY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)|TrEMBL
MRIIELYRQKAPLLSLEIFPPRMAYPLESVFDTVQELKRLNPAYISVTYGAGGSNRERTV
EIAARVKKEYGIEAQAHLTCIGHRQEDIKNILARLNREGICNIMALRGDIPEDEPEFDFR
RQEYHYAFELIRDIRAAYGDSFGIAAAAHPEGHPECPRLKDDIFHLKNKVDNGVDFLITQ
LFFDNRIFFDFWERCQAMGINCPVIPGIMPVLNAGQIKRMIYLCGASMPAGLLKLVDKYE
KEPVDMEKAGIDYASQQIKELLENAVAGVHLYSMNKPRQISEIVYNIGLASPGKY
>A0A2J9EXS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. FDAARGOS_256|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A417EF84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM33-3|TrEMBL
MKIRDILAKNEPTLSFEVFPPKTEDKYESVEMAASEIAKLNPAFMSVTYGAGGGTSQYTV
DIAASLKAKGVTPLAHLTCVSSTREKVHSVLEQLKAEGIENVLALRGDIPKDGKVENDYR
YASELIAEIKASGDFCIGAACYPEGHVESVNKTEDIQHLKEKVEAGCDFVTTQMFFDNNI
LYNYLYRVREKGITVPVIAGIMPVTNVAQIKRICSMSGTYLPARFKAIVDRFGDNPAAMK
QAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKGSLSEIIR
>A0A4P6XAB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. AAP5|TrEMBL
MTVSVKQMQEARLALAAPLFADIAGDARVSFEFFPPKTEKMEETLWESVQTLAPLGPRFV
SVTYGAGGTTRERTHATVARIARETDIPAAAHLTCVDATREEIDAIADEYWKAGVRHIVA
LRGDSPVAGQKFQSPVGGYENAAALVAGLRKLHPFEISVSAYPECHPDSASEAADLDNLK
RKLDAGATRAITQFFHEAETFFRFRDAAAKAGIDAEIVPGIMPIMNFGAVQRMSAMCGTV
VPDWMGTLFDGLDDRPAARQLVSATIAAELCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GIRGQPALVAAQAA
>M6TNC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Bataviae str. HAI135|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSLLDPDFVTVTYGAGGSTRDK
TAQILSQISKNYSVPTVSHFTCVGANKGQILETLKGIRSSGIVNLMALRGDPPKGEGEFK
KVENGFGNATELISFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVKNLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A4R8W3A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. RHLT2-21|TrEMBL
MQKTSDPACPGRIPFSFELYPARTDAAASALETTIERLAAAGPDFLSVTYGANGSSRRSS
LDVLSRILRTTNVEAMAHLTCVGSTHEEANRLIREFLDAGVRSFLALRGDPPAGAKEGEA
FLGDFGSAAELVQLIHRVQAEKSPYRESIIPGIPAARAVKPGREKVRIAVAAFPNGHPRS
RSSAQDIDTLLAKQAAGANLGITQLFFHADDYLCFAQRAREAGVLFPLLPGIMPVTSPAR
LRRIIELSGEPMPSDLSIRLEIEPTKEGQREIGIQHAIDLAGQVIAGGAPGLHLYAFNEH
ETVLEVLGGCGLLTAPVSAPTKLPATV
>A0A0L8VGP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces boulardii|TrEMBL
MSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKT
LALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVE
AGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
AILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETVANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPFKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWET
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKA
WRDEAFSIWSEWAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETDELWEMLLDQA
>Q0AYF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)|TrEMBL
MRTSEIFNNKTVLSLEIFPPRRTASIGIIYKTLEELQGLNPDFISVTYGAGGSETNTATL
EIASAIKNNYGIESVAHLPCINLNKDEVLNMLEGFKQAGVENILALRGDVNPARVPKQDF
RYASDLVSFIKENGDFNIIGACYPEGHSESPSLLDDIRHLKIKVDAGTDQLITQLFFDNS
YFYSFRERASVAGINVAIEAGIMPVVNKRQIERMVALCGVKLPKKFVTMMERYENNPEAM
RDAGIAYAVDQIVDLIAQGVDGIHLYTMNNPYIAKKIYAAISTLLVA
>A0A2L2T2T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium venenatum|TrEMBL
MHIKDMLHDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WEAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVADMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPSAERP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKAIQDIAELFVSYLNNKIESLPWSESPLTTEADEIREDLIE
LNKRGLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPSVFDKMMSRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLAEPI
ANGANGVNGTAATAVAN
>N4WNX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cochliobolus heterostrophus (strain C4 / ATCC 48331 / race T)|TrEMBL
MHISQKLAQAKREGKPTFSFEFFPPKTAQGVQNLYDRMDRMHSFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALREAYQAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDDVDELIDHLKEKVDAGGSF
IVTQMFYDTDLFLEWVRKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTKCHIPDDWTKAL
EPVKNDDVEVREVGKTLVADMCRRLIDAGITHLHFYTMNLAQATRMVLEELELLPDVESP
LEKPLPWRPSLALNRREENVRPIFWRNRQRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPLTIRDLSNLFVRYMEGKLESLPWSEQPITAEASSIRDDLID
LNRRGFLTINSQPAVNGVKSSDPVFGWGPRNGYVYQKSYLEVFVSPEHIAEIITRLDRDP
EFTYYAVNKNGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDVIDTWYLLNIVHNDFHATRGIFPIFNDLEVKDMDKPLHTPSADL
PNVNGSETANGTNGVNGTNGTHKEESPSLIDVAKAAAIEVTNGMKSLAVSS
>A0A2T2SIN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QH_2_67_10|TrEMBL
MKVTERLESADEPLISYEIIPPKRGGSAEQIMGVVEELMPYDPAFIDMTSHAAEVEYVES
GDGTWRRRVMRKRPGTIGLCAAIEARYGVDTVPHLLCKGFTREESEDALIELNYLGVDNV
MALTGDDPG
>A0A0D0HR25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus ayderensis|TrEMBL
MGLLDDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIESGAEIIQTN
TYGANYVKLARYGLQDDVKKINEAAVELAKKAAKGRAYVLGTIGGLRSTNKSTISLEEVK
RTFREQLYVLLNEGVDGLLLETYYDFEELQTVLSIARKETTLPIIAHVTLHDIGVLQHGM
PLAEALTELEQLGADVVGLNCHLGPYHMLRSLEEVPIPTRAFLSVYPNASLPQYRDGRFI
YETSEQYFEETARAFREQGVRLIGGCCGTTPKHIAAIARALSDRTPVYKKEVKQRHPIVV
QEEKQTTAPSLADIARTRRSIIVELDPPKKLGLTTFLEGAKALKEANIDALTLADNSLAT
PRISNVAVGTIVKQQLGMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRL
EKKIECGAHYFLTQPLYSEKQIEDVYEATKHLPTPIYIGIMPLTSARNADFLHHEVPGIT
LSDDIRNRMAMCANDRVQSTKEGLAIAKALIDAAFDLFQGIYLITPFLRYDMTVELVRYI
HEKERLAKERTVYYG
>A0A7Y8H8W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MYFREVLHSKKFVVTAEIGPVKGTDVREMIEDAELIKDKVDAINVTDLQSSVMRLGSMAV
CHLLKDIGIDPILQMTCRDRNRLALQSDLLSAWVLGIRNVLALTGDHPALGDHPQAMPVF
DLDSITLLKVIRRLNEGFDMAGNQLKGATDFLPGAVVNPGADTEASHEMQIIKMEKKIEA
GARFFQTQGIYDLELFEKFMKRVEGFNTPVLGGVILLKSAGMARFMNKNVAGVFVPESII
KEMEEAKDKVKTSVSIAARLIKGMKELCQGVHIMAIGWEKKIPLVLEEAGL
>A0A243CNL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar vazensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6J4QW19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Rubrobacteraceae bacterium|TrEMBL
MQTEQERSKVFSVELFPPRTPAGEENLAAALGPLSALGPSFFSVTFGAGGTTRSGTIETV
VKTMDETGIEAAPHLSCIEGTRESIGEFLDRYKDAGVRRIVTLRGDLPGDMESPGVFSCA
TELVAFIRERTGGYFHIEVGCYPEFHPESESAATDLGYFRDKVEAGADSAMTQFFFNADA
YFYFVDEVERMGVDIPIVPGIMPIWDYEKVARFSDGCGAEIPQWLRKRMEAYGDDAASQR
ELGIEFVTDLCQRLLDAGAPGLHFYSLNRAEPTSTIWSNLGLKPTAT
>A0A1Q7WNK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ktedonobacter sp. 13_1_20CM_3_54_15|TrEMBL
MQHDFLEQLQQHPLLCDGAMGTLLYARGIAYERCFDELNLTRPALIQGIHSEYISAGAQI
IETNTFGANRAKLEAYNLEGRVRDINRHAVKLAREAREISGQSVFIAGAVGPSGRPLQAP
DEQRLSELRAIFREQIDALLVGGADLLILETFSSLAELRQAVLAAQDVGGLPIVAQMSFY
EDGHTLSGQSPARVAAVLNDLGIDVMGANCSVGPAATLDVLQEMIAAARLFLDNEQAIPQ
MFSAQPNAGLPTRIGNRFFYMATPDYFADYAVRFARAGVQLIGGCCGTTPHHIAAMRKAL
NDAYGAATPSIPGSSRETLQAKPVEITNGKVTIAGLIEEEVILPQQGTKTRLQEKLAARE
FVVSVELDPPKGLNPAKILEGAAMLQKVGVDFINIADSPMARVRMGCIALARLIQDHLGI
ETIIHFTTRDRNLMALQSELLGAHALGIRNILSLTGDPLHVGDYPNTTGVWDLDSVGLIQ
VLRRMNEGHDAAGSSIGAQASFHIGMALNLNMTEQETEQEIDKYRRKIEAGAHFIMTQPI
YELARLECFLARVGKPPIPMLLGCIPLHSSRHAEFLHNEVPGITIPDDVRSRMRAAGDQG
HEEGLKLAQELLTSARSMIQGVYLMPSYGRYDVVSKLTKMLQMQPTP
>A0A7W0F785|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSFRDILNSGKFVVTAEVGPPKGTDIKEMIHHMEILKGKVDAVNVTDNQSAVMRICSMAV
SKIAMEHGLEPIFQMTCRDRNRIGLQSDLLGANILGIKNVLCMTGDHVSAGDHKGAKPVY
DVESVQLLKIVDGLNNGKDMSGNELKGATDFFQGAVVTPEANPIEPQLIKFEKKIRAGAK
FFQTQAIYDIEKFKDFMKHARKFPVKILAGFVVLKSAGMANFLNNNVPGIRVPQSLIDEL
KASSDKGGSGGGKERALDTGMNITARHIKQLKEEKICDGVHIMA
>A0A0S6UPW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. DOA9|TrEMBL
MTDVTTPATADGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYGAGGST
RERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHDVGVRHIVALRGDPAGGIG
TPYSSHPEGYQSSAALVAGIKKRHGDIEVSVSAYPEKHPEARNFDADIDTLKAKVDAGAT
RAITQVFFDNDLYFRYLDRVRARGIDIPVVPGIMPMHNFKQARNFVTRAGTTVPDWFAAK
FEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAKSAQ
KAA
>A0A6J4S2L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Rubrobacteraceae bacterium|TrEMBL
MSFDLRERADSRVLIGDGAMGTLLAERGVGFGHPYARANVTHPEMVAGIHEEYIRAGAGV
IETNTFSANRFKLEVHEIEERVRDVNEAGARLARKAADGVKTGDGNRALVLGAVGPLGRS
LCPVGPVTESEARAVFLEQAEALLEGGADALVLETFTDLVELRIAHEAVRGLGVPTVAYK
TFVEDGETLSEGLPGRAAREISSLGVDLAGANCTVGPQRMVGIVEGMSAEVGPVAAFPNP
GLPQLVDGKVRFRRDVDHFALYGRRLAAAGARLVGGCCGTTPEHVKALADALRDFRPEAT
AARGVHVRTIEEEGPAEAIDGPSTELAEKLRTGFAVAVEVDLPRGNDITKVVEAARRLKG
RGVDAIDISDGARARLRMHPVAAAKIVQDEVGIEAVAHISCRDRNIIGLQSDLLGAAALG
VKNILAVTGDPTQIGDYPEATGVFDTDSVGLVHVLSKMNGSEDLAGNSIGGPAGFLIGSA
FNPTAEDLDGEIEKLRRKIGAGAHAFWTQPVFEIGALEMALERMGDLDVSLLLGLMPLRS
ARQAEFLHHEVPGVNIPKPVRERLTALSPQDAPRYGVEVAQNLLAKAQPLVNGAYIMPPA
SAPDLAGDVLEAIRLKA
>A0A851JAV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Donacobius atricapilla|TrEMBL
MVNETQLSCSASSSSRSDGSSSGGESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDLV
KHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLRF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6A9JS37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MAASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A1H1AAE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora saharensis|TrEMBL
MTRVVDRLQPGRTVFSVEFFPPRNDDEERILWKAVRELEPLDPAYVSVTYGAGGSSRDRT
IRTVGRIARETTMPPMAHLTGVDHSKSELRHVVGSLANEGIRNILAIRGDPPGDPMGEWI
PHPEGILYADELVSLIRSCGDFSVGVAAFPHMHPRSTDLETETDHLVGKIRAGSEFAVAQ
LFLQPEYFLRLRDRLAARDCHVPLLPGVMPITTPKVLNKFQHLAGVPVPPEVSAVLDPLQ
DDPQAFRAAGIDLTTKLCERLIAEGVPGLHFYSLNRAKATREVVDNLGLAEGVLQPA
>A0A2E8F391|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomyces sp|TrEMBL
MKIKDILNNTRTISCEFFPPRTEEGIPDVFNAADRLKAYCPDFVSVTYGAGGSTRAFTER
ITSELKEQSELEVMAHLTCVGQSKEEIHSVLERLDQTGIENIIALRGDPPKGETDFVPTP
GGFQHASELIEHIQDNFQMGVAAACYPEGHTESPNLNSDLDFVKQKVDKGADFLITQLFF
DNNDFFEFLNRARNAGIDVPIIPGLLPILSAPQIRRFASMCGASIPPDLDRQLDKFDDDD
DGARALGIEHATKQVEELWASGIPGIHFYVLNRSYSVSMILDNLKLPGHNGLA
>A0A0X6ZT86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. D14|TrEMBL
MIIKRITHKLPDISAASIIPASIEASPAQVLGSTDLADLFPQGVRVYLTDTGAASQERLV
EAAGHLRDLGYEPVPHLAARRIPSRAAFEEQVKRLAGEAGVTDVLVVGGGVDRPAGPFAS
SMDMLSSGIFDRCGIRQIAIAGHPEGSPDFNEETAMAALRLKRDFAERSDAVMRIVTQFG
FDPARFIAWAEGLAASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESIVGPIERHWQTNPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGAADRSAS
PDSMAG
>A0A2I1UH57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. dentisani|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDMVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1A0F596|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. G11|TrEMBL
MSRHEHPLGISFEFFPPGTDAGRDKLIQTRDELAARNPRFFSVTYGAGGSTQARTREIVR
QVSQSGVTTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRDETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
HFVDKARASGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIADF
GTDVVSRLCQRLLDGGAPGLHFYTLNQSKPVLKIVDNLSG
>A0A3G2T126|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter wuhouensis|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLDDFN
GKGTPVAPHLSCIGDSKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQRFCDKARAGANAALTQFFFNPDAYFYFV
DRIQKEGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A3N2BFV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bogoriella caseilytica|TrEMBL
MSSPSLAPSAPSAVTPADAPSRSTAFLVQRTRRRTLISFEVFPPRPEVAPTQAWQAIDTM
AQAGPDYFSVTHGHQQSAHAHRELIRHLLEHTEVPVLAHLICAGRTQDDLRALVAGLITE
GVRDFLALRGDPLPGATEWVDEPSGFNRAAELVRAIRQIEEERLHPPAGIGARPISISVA
AYPRSGAPRDYSRDLHALWEKQEAGADYAITQVFYDAEDYARLVDDARSQGIHLPIVAGI
APLTSAKRLQRLQQITGVPVPEHLLAHLEGVDEAELGRRGVAATLHLIDAVLELGCPGLH
LFTFNRYRAPLSILEHLRIRDAARQHRAGTAAASAATALP
>A0A5D4JMQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces parvus|TrEMBL
MALGTASTRTDHARTVREMLATGKASYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A2E9P0F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MTIRYEANPPKILPDSDTNKAILKFIERIKKISNKCDSIHITEXVLGFQRVSPXEVGKII
KKEIPNLPITVSLRVRDKTEKEILEFVEKCXTIGFSGILILMGDPSQTGKEDSGQIPSAV
INNLRKQXVDSKIDLYLSISNKPNFTKIGKKIQAKPKGFMTQVVQNIEQVQNLSDNLKGF
KIIPIILFPSEKNEKSAKFLNLDLXSYSQTFNEFVKRVHXITEDVXITSPNDFKGLDXFL
EKQII
>A0A7S0E287|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hanusia phi|TrEMBL
AGQGSAMAPVNTSSVGRDRKGCVCDKIRHHIENGSKFYSLEFFPPNTLDGARSLIARVDR
LAKLKPKPLFVDVTWDIESGKRAIETLVAAKAVCSLDVQMHLTCTGITRSMADDLLVEAM
DAGIRSILVLRGDPAPGKSEWEPVAEGFKNASELLGYIRQKYGDFFSLSVAGHPGKHPAS
ASQEEYLQHLKRKVDCGADFIVTQMIFKASDYTEFVSSCRGVGIDCPIIPGVLMIPPSLE
KLKTVCDHCPVEIPEDLVDLLKSCGSDRERVREAGRAYMEKACSEMLSSGAPGLYIYTLN
LEKSAHELISNLDIKSLDPKSDAVVRPLPFPRPREKETVRPIFWASNAISYLARTRNWSA
DFPSQWGKVND
>A0A1E9A7H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. HMSC071G07|TrEMBL
MDKLLHKLQTQVLVGDGAMGTILFTEGLDTCPEAYNLTHPEKIEAIHRSYIEAGADVIQT
NTYGANFEKLKAFGLEHKVKHIHQAAVAIAQRAAQPETIILGTVGGFRSVTQEDLSLSTI
LYHTELQIETLIQSGVDALLFETYYDLEELTAVVKLAREMTDRPIIAQLTASNTHYLKDS
TEINRAIQHVVKCGANIVGLNCHHGPHHMQQSFSHIDLPQDAYLSCYPNASLLDIENQEI
RYSDNAAYFGKMAQKLINEGVRLIGGCCGTTPEHVRYIKQAVKDLSPVTRKNVIPIKKRE
TNQAIPTHKKNLTSIVKQRPSIIVELDTPKHLDTSTFFDNVQQLDQLGIDAITLADNSLA
TVRISNIAAASIIKQQYNIEPLVHIACRDRNLIGLQSHLLGLSLLDITEILTITGDPARI
GNLPGATNVYDVNSRGLTEMALRFNQGINTDGAELKQRTHFNIAGAFDPNVRRLDHAVKR
AEQKIKHGTHYFITQPVYSSDKIQEIYEATKHLETPFYIGIMPITSYNNALFLHNEVPGI
TLSDDILEQFEAVKDDAAQTKALSLKLSKALIETVHRYFNGLYLITPFQRVDLTIELAQY
SQTITSTKQEALL
>A0A2E4JRX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MNISYEMNPPKIKRNTTFDLDLLKQDMDKFYERISQLVALTDSIHLTDSVFGIPRISSIS
AAHEIINIHSGIKLRCSVRARDKNLNAIIQLVSDAIMMGVEGLLIIKGDKPENPSIDSGL
LSSDIVKTLNEQGFGDKIKLFLSLPNNPDLNQIQKKMEAGPFGFITQLISSLHHLQKIVD
HVKSNNRRVIPMIMVPSPKNKESATLIGLDWREYENDTYLFIKQALAMCGEVLITSPNSF
NGGMNLLNKIRVEIN
>A0A395JSR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. WD7|TrEMBL
MKITDHIKEANGKTLFSFEIIPPKKGNNIQQLYDNIDPLMEFNPPFIDVTTSREEYVYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYVLVDCHYLGIQN
VMALRGDAMSHQKYFIPNKDGNAYAKDLVAQIKNLNKGKYLHNVVETNNCSDFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFAFVDAAKKAGINVPIIPGIK
PIATKKHLQLLPQVFRIDIPEELISEVDKCKTNKDVRQVGIEFAINQSKELLAAGVPVLH
YYSMGKSDNIHAIASELF
>A0A533X831|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MVECLKLRQKLERRDFLRIVEVFPPNFTAERDREPLIGLRQKTRDFLERVKKIQNLADAI
LVADVKDLSRLKLGTIYSAAMVQEEVGIEAVPVITARDSNRPAIRSAILTALSLGLDSLM
FVWGDTYADDGAKNVYDYTGVGEMMIEAGALFERAGVRPTFFAPIDLATLDAPRGRRLAH
SRLKSGAEYLLAQPPTADVSYTFPSHMRTLRRRRLNSRVLLNVFPFRSSDDIEYCRKKFG
WDIPPHLGAIAEKGGEPELLSEAKRVADRLRAVGCQGVYVSTRGRPELARFILD
>A0A6P4YFJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Branchiostoma belcheri|TrEMBL
MSSSGYTSSGASTPSNGSRPSSPGPGVPYVKLADRIEAKINRGERWFSLEFFPPRTPQGA
ANLISRFERMVQGGPMFMDITWHPAGDPGNSDKETSSMSIACAALNYVGHETMLHMSCCN
STKDDIRRHLDKAKELGIRNILALRGDPIVGDEWKYVEDGFNYATDMVRFLRAEFGDYFT
VCVAGYPHGHPDSPTYEEDLQHLKEKVDAGADFIITQLFFKADRFVKFVEDCRRIGINVP
IIPGVMPIQGYHSLRNLVKLSKLEIPDEIREAIEPIRDNDEAIRNYGVHQAVTMIRELFD
SGLVNGLHFYTLNREVATIQILKQIGLWTEDIQRPWPWKRTANYNRCEEEVRPIFWASRP
KSYVYRTQEWDEFPNGRWGSSESPAFGELNDYYLFYLKPNAKKEELLDMWGHELTCLQDV
FDVFTNYITGKDSKNGKKVRKIPWNDDDLAAETGYINDKLARINSRGVLTINSQPNVNAA
PSTDPVVGWGTPGGYVFQKAYLEFFTSRENVQALFKVLPKYPNVNYHIIKYEGEDDYTNC
DQQQPIAVTWGVFPGKEIIQPTVVDPVSFKFWKDEAFTLWTEYWGQLYAENSKSRELIQH
IHDTWYLVNLVDNDFPRENILFTVIKDMFAEADLQRAKGKGQTNGVNGVHHVDDDGVFVN
GAGDVPKNTCAEQIQRNAEAEIVQAL
>A0A7X9ZIF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus capitis|TrEMBL
MSQFLNQLQNNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGANVIQT
NTYGANFEKLKTFGLEHRVKEIHKAAVQIAKRAAHHDTFILGTVGGFRGVRQDDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELKSIVVATRRKYEIPIIAQLTASNTNYLVDG
TEINDALKQLVACGANVVGLNCHHGPHHMQRSFSHIELPDNAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIRYIKTAVQGLTPIKDKKVVPITKKS
NHKPTKVVKQNLTSKVKNGPTVIVELDTPKHLDTDTFFENVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQQYDIEPLVHVTCRDRNLIGLQSHLLGLSLIDVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A7K2UBX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7813|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTNFVD
KCRAGADYAITQMFFQPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>K6WF66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia rhizosphera NBRC 16068|TrEMBL
MAPQETTSAAELLARTRDGVLFYGLTPPRATTTAEQADAVAEAALARLRSVQVDALIVYD
VDAEADRSSTPRPFPFMPMMDPAVFLDRHLAGWTGPVVVYRAVSKYTGEELSDWLSETSR
DRVLTVLVGAASRHQVVRTSLSEAYRRYAALSRPPRMGGVVIAERHANAGTEHQRMLRKQ
DAGCEFFVSQVCYDLDNTRTLLSDYAYGCRDQGLEPRPVVLTLAPCGSVKTLEFMSWLGI
ELPGWLRTEIARSGDPLTVSYEQCVVNAQVLIAFCRRLGLPFGINVESLTNRKVEIDASI
ALAREIRSQLD
>A0A1I4MH27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas communis|TrEMBL
MKSQKVFPPTFSFELFPPQTPEGVEKLRAARYQLAQFKPKFFSVTFGAGGSTRDRTFDTV
LEMLAECHPVAPHLSCIGSTRENIYSILRKYQESGIRHIVALRGDLPSGMAQPGEFRYAN
ELVTFIRKEFGNTFKMDVAAYPEYHPQARSAQEDFRNFINKIEAGADSAITQFFYNADAY
FHFVDMCETANLNVPIVPGIMPINKFSQLVRFADNCGAEIPRWIRKKLEGYGDDIASIHA
FGLDVVTDLCERLLKAGAPGLHFYTLNSAVLTTKIWQRLGL
>A0A1R1XGN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium culicis|TrEMBL
MANLGDRLSRMKSWNPLFSTVTWGTGSSDCTQSIDFSSKLQNEFNLDAVLHLTCSNMSKE
LVDNSLKTAKSKGIRGILALRGDIPLELTSISNNSTGNNNCFKYASDLVEYIKSIPEYSE
YFTIGVAGFPEGYTSATISETFDSATNSSSSASRNFNSSSTTQLDKEKDELKWLSYKVSK
GADFILSQVFYSTDKFVDWYKKCRDYGITVPIIPTILPIQTYGSFKRIINLTKVSVPPSL
NDQIELVKSDDLMVKQIGIDFCCNQISTLTKECNILGFHFSTLNLENSLLAILTRSGLLR
TFNNPSDLSSLPSKFSASNTNSTLPVGGESATWDEYPNSRWGDARSPAFFNESIYGQSSF
INTDQLLQWGFPKSLDDINTLFSKYISGDIPSLPWTSDNINSSNSDFVISVLNYLPKVGI
WPMASQLAVDGAQSSDPEFGWGPANGYVYQRSFIEFFAIEPVALKILEHLKNNTKQDFSY
YASKLNFDTNEPLILSNAVVNNASFDPSINSHLLEIESTALSWGVFPSSPVIQSALIDKL
NFGYWSKEAIQLWRVWASQIGSFSKESKQFIDSVADSVYLINIVANDYKTPEKLFCFLRE
EF
>R4YR10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleispira antarctica RB-8|TrEMBL
MATDNLISKIKNRESGIVLYGITPPKKGTSEEKITEISARQVDRLQDLSVDGLVLYDIQD
EKSRTDEERPFPFMETLDCYDYSQQHLTNLKIPKIIYRAVGKYSETELSDFLTQADPQDN
LSIFVGAASKSQEVTLSISDAYKIRADTQSNMLLGGVVIPERHQSKGDEHLRVFEKMAQG
CSFFISQGVYDVNASKNFLSDYYYYGKENNIPLVPILFTLTPCGSAKTLQFMKWLGISIP
KWLENDLIHSNDILQRSVDVSEQSYRELKAFADEKGIPVGCNIESVAIRKVEVDASIELL
ERVSR
>A0A4R1B708|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacter taiwanensis|TrEMBL
MEIGDVRYEVIPLAGVEELVSEHVPKEVALTITASPVRGMGPTVELAERLAGAGWRVVPH
LSARLVRDEGHLEEIVGRLQGAGVRDVFVIGGDAREPAGRFEGSAELLRAMHELGHCFEE
VGIAGYPEGHPFIGDEDLSRAMEKKAPYATYIVSQICFDAELITGWAWRVKRRGIELPIW
VGVPAPVESKKLFRISTRIGLGESARFLKKQRNWLIRLFLSSFSSSSSGYNPDPLVDALA
PALLDPKSNIEGLHIYTFNELEKTEAWRAAKRWKLAKSEHEEKNF
>V9HPW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptoanaerobacter stomatis|TrEMBL
MKISDILSKNKINLSFEVFPPKSDVALGAVMDTVRDIADLKPAFCSVTYGANGGTSENTV
KIASYIENELNVCALAHLTCVLSSKEDIDEKLQKLKENNIDNILALRGDIIDEELFKNKK
DLIHSSELMSYIKDDYDFCIGGACYPEGHLESKSKDEDVEYLKLKQDLGADFLTTQMFFD
NNIFYNFMYKLRNKNVNIPIIPGIMPVTNVTQLKRIRQLSGAQIPPKFLSIADKFKDDVP
AMKQAGIIYACNQIIDLISNGINHIHVYTMNDSDIAKRISDNLSYILEK
>A0A2K0WTC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella nygamai|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDVAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIGESRGSETDSEIMLTMVVNNDFHDNKTIFELLKG
LEVKDLTTPATPLTESVGNGAVDTEPIANGTAATAVAN
>A0A501XFI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sandaracinobacter neustonicus|TrEMBL
MTAEDLAAGAPLYADLPGDIEVSFEFFPPKTEKMAETLWSSVQTLAPLKPRFVSVTYGAG
GTTRERTHATVARIVAETDIPAAAHLTCVDASKDEIAAVADAYWEAGVRHIVALRGDPPV
KDGQFQKFVAHPQGYRDAADLVAGLAARHPFELSVGAYPETHPEAASAEADLAHLKRKLD
AGASRAISQFFFEPEAFFRFRDRAAAAGITADLVPGILPVASFANVQRMAGQCGTHIPDW
MARLFGGLDDKPEARQLVAATIAAEMVRRLYAGGVRHFHFYTLNRAELAYAICHLLGVRP
Q
>A0A7W9ZHX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novispirillum itersonii|TrEMBL
MTESQQAAITKPIEVSFEFFPPKTEKMQENLWTCVKRLAPLAPSFVSVTYGAGGSTRERT
HDIVTSITRDFGIPAAAHLTCVAATREEVNAVAQEYWDAGIRHLVALRGDPPDGETDYLP
HPGGYAYAADLIEGLKAVADFEISVAAYPEVHPQALSARDDLDNLKRKIDAGATRAITQY
FFDADTYRRFVDRAQAAGIGVPIVPGILPVTNFSQVVKFSRACGTTVPAWLRDRFEGLDD
DPRTRELVAATTAAELCEDLQKDGVRNFHFYTLNRADLTYAICHILGVRPQRPAAA
>A0A8J3J4G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinocatenispora rupis|TrEMBL
MPGGDPSIGQLVRDSAPTFSFEFFPPKTEQGDRLLWQAIRELEVLHPSFVSVTYGAGGGT
RDRTVDVVERIATETTLTAMAHLTAVNHSNAELRNLVGRMAAAGIRNLLAVRGDPPGNPM
GEWVKHPEGVSYAADLVRLIRESGDFSVGVAAFPYKHPRSSDVDSDTRHFVRKCRAGADF
AITQMFFDADDYFRLRDRVAALGCDVPIVAGIMPVTKMSTLERSEQLSGAPFPPALAAQF
ERVADDPEAVRRLGIEQASELCQTLLDGGVPGIHFITFNRSTATREVWRNLTLPTPVGG
>A0A8D5JQN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomarina profundi|TrEMBL
MKTESVLEKVLAAGHLAVTSECGPPRGAQPDKVREKAKYLAGIVDAINVTDNQTAMVRMS
SLAASTIIKQEGLNPLLQVVSRDRNRLAMQADIIGAYSLGIDTMLCLSGDHTKFGDHPMA
MNVHDIDSIQMIQMVKQMRDEEKFQGGADLKGARRCLSVLLLTRLPTPLNCVFFAWKRK
>C1AU72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus opacus (strain B4)|TrEMBL
MTRTPSIVDRIRSSGDGRVPFSVEFSPPRDEAAEARLWRAVREFERMGPAFVSMTYGAGG
STRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRGISNILVLRGDPPGD
PLGEWEKHPQGVEYAEELVRLVRDLGDFHVGVASFPEGHYRAPDLAHDTRYLVSKLRAGA
EYSITQMFFDVDDYLRLRDRVTAYDPEQGAKPIIPEIMPITSLGSVRRMLELSGSSLPAH
LEKRLAAAAGDGPEENRAAVREIGIDLATEMSERLIAEGAPGLHFITLNFARATSEVLAR
LGDKVGSGVADPAPVTPAPVS
>A0A8D5JNJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomarina profundi|TrEMBL
MFIGAAANPFADPFELRVLRLEKKINAGADFIQTQCIFNVDKFEKWMEGVRARGLHKKCY
ILAGVTPCKSAGAARFMATKVPGMDVPQEIVDRISAVPKEKQAEEGIAICVETIERLKKV
EGVAGFHIMAIEWEEKVEEICERAGLLPRPQV
>A0A7H1AND4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. 169|TrEMBL
MTSLSFEFYPPKTDEQRGQLDRTAAKLRSFAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
RFESAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYAAELIDFI
RAEHGDAFRIEVGAYPETHPQAADALTDLKHFKAKVDAGADAAITQYFYNADAYFHFVDA
VHRLGVTVPIVPGIMPISNFSQLRRFSEQCGAEIPRWISRKMQAYGDDSTAIRAFGSEVV
AQLCQRLLDGGAPGLHFYTLNLAKPTTSVLKLLRS
>A0A8F7XVX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus rubneri|TrEMBL
MTKQTPSLSFEVFPPNPEVGNAKLLRALENMQELAPHFISVTASNNKYNIKETTVALANH
IQNELSIPTIAHLPAIYLSKEKVADTLHDLDQVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFDVIGACYPEGHPDSPSQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVHHATKALFDHQPNLEVI
>A0A830ESU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula sebkhae|TrEMBL
MALGTRAVSDSQGVRTLLTSARFELMPFESFDEEITHLPDDATIAITTSPQLGIEKTVEK
TEEAAAMGYDVVPHIAARYVEDRAQLESIAERLEQAGITDIFVPGGDREEPAGEYESALD
MLEALAETAYSFEEVGITGYPEGHDFIDDETLAESMTQKAPYATYIVTQLCYDPDAVLEW
VEDIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDDEYNVRGVHIYTFNQTPDTEKWRHDRLDS
>A0A7H1RK78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomonas sp. XSG|TrEMBL
MLPISFEFYPPKTDEQHSQFDRTVRKLKAHAPQFMSVTFGAGGSTLSHTPETVQRLRGEH
GVDGVPHLTCVGGSREEIRTLLKLYRALGCTRIVALRGDLPSGMARSGDLRYASELVRLI
RDEHGDHFHVEVAAYPETHPQAEDARIGLDHFKTKVDAGASGAITQYFYNADAYFRFVDD
ARAQGIDLPIVPGIMPIANFSQLRRFSEACGAQIPRWIDQRMRAFGDDADAVREFAADVV
AGLCRRLVEGGAPALHFYTLNLAKPTQTVLQRLA
>A0A2B7Z4J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polytolypa hystricis UAMH7299|TrEMBL
MHIKDKLAHAEATGKPGISFEFFPPKTAQGVQNLYDRMDRMHGFGPSFIDITWGAGGRLS
ELTCEMVNVAQTVYGLETCMHLTCTDMPREKVDDALQAAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIREKYGNHFDIGVAGYPEGCEDNDDQESLMQHLKEKVDAGGTF
IVTQMFYDADIFIAWVKKCREVGIMVPIVPGIMPIHTYSAFIRRSNWAKIRVPPEWLEAL
ESVKNDDAAVRNIGKTLVAEMCRKILKAGIHHLHFYTMNLAQATRMVLEELGLVPSQGTP
LQKALPWRQSLGLHRREEDVRPIFWRHRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDV
YGVGLKGTNEQNVKLWGEPKSIKDLSNIFIQFIDGKVDRLPWSESPITEESEIIKPELID
LNSRGFLTVNSQPAMNGIHSSHPVYGWGPKNGYVYQKAYLELLISPQLIDEVIQRIEKNP
DLTYYSIDKSGKLKTNTTDSPNAVTWGIFASKEIIQPTIVETVSFLAWKDEAYTLGDDWA
KCHPANTPSRHLIQSVMDEWYLVNIVNNDFHKTHDIFDLFKDLTVKDLDTEIEVPTTDGA
KDVESATTDKQTPQPNGHAPAQANGTNGVGPSPSKATEVTA
>A0A364MZZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stemphylium lycopersici|TrEMBL
MERITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDQALEQAQVLGIRNILALRGDAPRSEE
YRDEDTPPEQDSNKDFTWATDLVKYIRKNYGDYFCIGVAAYPEGHSDQSHPDNQDPEADL
PYLVKKTKAGADFIMTQLFYDVEAYDKFETRLREHESGVFKTIPIIPGLMPVQSYKILLR
TTKLSHAKLPTDILTRLDAVKSDDELVKQVGVKIMDEMVEHIKARPDTCRRGFHFYTLNL
EKAVSHILEDTHLIPNTVVEDDEVIVETTPAINLEPPPNGFVPHRRRSSAVNSGPRNRVI
ISQHSATKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKGDISTLFRRHIEGDLEAIPWSEQSLSP
ETLTISKQLLALNAKGWWTVASQPAVNGVKSSDPVFGWGPKNGYVFQKPFVEFFIPASEF
AALKPKLDAHDQVTYFAGNAAGDFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIWQEWQRIYPPRSATSGLLGGLRRDYWLVNVIWGDFVNGEGLWEFLEQ
>A0A2E9RTJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MGKTKTIVERFTSGKPLFSVEFFPPRDDAAGENMLRAAQALQGYEPDFVSITYGAGGGTR
ATTLKYAGMLKQQCGFEVMPHLTCVGHNEVELMDILQDFESAGFRNVMALRGDPPKGESQ
FQAVEGGFSHADELVRIIRRNLPNFGIGVAGYPEKHPESPDPADDVQRLAHKVSCGADFV
TTQLFFDNEFYFDFVRRCRQAGITAPILPGLLPVLSLAQIRRFSSMCGAALPTELEKRLE
DAGENGAQQVGADWAYEQIKGLLDGGAPGFHLYALNQSKATTSILERLREKVSP
>A0A3B9FMZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MAKGKSIREFLEAGKPLFSVEFFPPRDEAGGERILATAKSLAPHQPDFVSITYGAGGGTR
ATTMRYARILREEHGFEVMPHLTCVGHTRDELLEILDDFAEAGFCNVMALRGDPPKGETE
FKAVPGGLRYGSDLVTLVRERFPHFGIGVGGYPEKHPEAPDMATDLSHLKTKVDAGADFI
TTQLFFDNRDYLDFVAACRNSGIEIPVLPGLLPVLSLGQVERFCTMCGTSMPGGLRRELE
AEDKKDQPKVGARWALEQVRGLLREGAPGFHLYALNQSASTLAILEGLKGD
>A0A329MMK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus contaminans|TrEMBL
MKQDLRQALKERTLTGDGAMGTYLYHLGLPVGISYEELNITQPDVIADVHRRYYDAGARL
IETNTYTANREKLSKFGLELDVAAINRAGVELARKAVGADAYVVGAVGSIRSGRRRVVIN
AQLEDDFREQMEALLEAGADGLLLETFYEHDELLAALRVARSLTNLPVICQFVTEDSGVT
RDGIALDTAFAQLASEGADVVGFNCHSGPNGILRALEKLTPIPNVPFSVYPNAGLPKLVD
GQYTYSAPPEYFASMSGRFAALGARIIGGCCGTTPEHIAAIAQALAGGAAAAPVQSPAAG
TAAQHAEPDRAPAADAEQTAEIVQQPCVCGGEHDDELSLVELVKRRHTVIVEFDSPRGLS
VEKFMKGSETLRDAGVDAISMADNSLAQTRMSNVSTGYLVKEKLGVRPLVHIACRDRNSI
GMQSHLMGLHALDIDHVLAITGDPARVGDLPGASSVYDMTSFDLIRMTKQLNGGLAFSGK
QLKEKAKFVVGSAFDPNVKYLEKAVQRMEKKIEAGADYFMTQPVYDPAIVEKLYTMTRHI
SAPIFIGIMPLISGRNAEYLHNEVPGIRITEAARSRMAGLEGEEGRRAGVEIAKELIDEV
IRYFNGIYLMTPMMFSEMTAELTKYVWEKTGAKTITSCP
>A0A3L7I9U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cricetulus griseus|TrEMBL
MKPLGRSRNPTMVNEGSGSGSGSGSGSESSKDSSRCSTPSLDPERHERLREKMRRRMDSG
DKWFSLEFFPPRTAEGAVNLISSGDEYAQPSDPASAWMRSRYCRLSHLTNKDTVPRQGPR
LKKEIPPRFDRMAAGGPLFLDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETVLHVTCC
QQRQEEITGHLHKAKQLGLKNIMALRGDPVGDHWETEEGGFSYATDLVKHIRSEFGDYFD
ICVAGYPKGHPEAESFEEDLKHLKEKVSAGADFIITQLFFEANTFLSFVKACTEIGISCP
ILPGIFPIQGYTSLRQLVKLSKLEVPQNIKDVIEPIKDNDAAIRNYGIELAVSLCRELLD
SGLVPGLHFYTLNREVATMEVLKQLGMWTEDPRRPLPWAVSAHPKRREEYVRPIFWASRP
KSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESV
FKVFERYLSGEPNQHGYTVTCLPWNDDPLAAETSLMKEELLRVNRLGILTINSQPNVNGK
PSSDPVVGWGPSGGYVFQKAYLEFFTSREIVEALLQVLKKYELRVNFHIVDVQGKNITNA
PELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQY
IHDNYFLVNLVDNEFLLDNCLWQVVEDTFELLNGHSVKGDAQAP
>A0A7C1Y6T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MAKISDLLAGGPTVSFEFFPPKTDAAALTLGRTIAELEPLHPSFVSVTYGAGGSTRHRTR
DIVVWIARETDITPMAHLTCVGHTRAEITEILENYREAGIENILALYGDPPADAGPDYDH
GDFRYAVELVEFIKEFGGFSVGVAAHPELHPRSPDRATDRRFLAEKLAVADFGVTQFFFE
ADHYFRMVEEVAEHGVTTPIIPGIMPVNSVKAIKRMAELSGAHFPDWLAERLTAAADPAA
VRQVGIEVATEMCRELLEGGVPGLHLYTLNRSNATREIYAALGTAVGS
>M0MZQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halococcus thailandensis JCM 13552|TrEMBL
MSVTRQSAADDGVARLLDDPRFELMPFDSFADEMDELPADATIAITTSPQLGLDATVEWA
EKAAARGFDVSPHIAARYVRDVDHLDEIARRLADAGVTDIFVPGGDREEPIGEFDSAYAL
LDALEGLDHEFEEIGITGYPEGHEFLDDDTLADAMAQKAPYATYIVTQLCYDPEAVVEWV
EDVRDRGVELPVEVGIPGVMKYDKLLSISRKVGVGDSVKFLKKTTGVVGFVRELVGSRGR
YTPDELVEGLAPYADDPDYDIRGLHVYTFNRTEDTESWRYGVLDE
>A0A8J8BA30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aestuariicoccus sp. KMU-90|TrEMBL
MAQPAVSFEFFPPRDIEGTFRLWDAVQVLAPLSPRFVSVTYGAGGTTRDLTRDVVATLHK
HSGLKVAAHLTCVNATRDETLGIARGFAGSGVSDIVALRGDPPKGSAGFEAHPEGFANSV
ELIAALKEAGDFTIRVGAYPEKHPEATSAQADIDWLKRKLDAGADEALTQFFFEAETFLR
FRDACAKAGIEKAVVPGILPIENWKGVRRFAENCGTPVPAWLSDAFEKAERDGRTDLLAT
AICTELCSDLIDEGVDKLHFYTLNRPELTRDVCFALGVTPKVRLEKVA
>A0A194VW94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Valsa mali|TrEMBL
MHIKEMIAEAEKTGAPSFSFEYFPPKTLTGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVSQAQAYLGLETCMHLTCTDMGLEKVNEALRKAYKAGCTNILALRGDPPRDKEK
WEAADDGFNYAKDLVAHIRATYHDHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFLRWVGKVRARGIDIPILPGIMPIATYASFLRRASHMNCKVPQEWMDAL
EPVKNNDVAVREVGKTLVADMCRKIVAAGIPHLHFYTMNLAQATRMVLEELDWMPSDRSP
LKQALPWKQSLALGRRYEDVRPIFWRNRNKSYISRTMDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSVKDVATMFVKYLNKELDQLPWSEAPLTSEADSIREDLID
MNTRGLVTINSQPAVNGVKSSHPIHGWGPANGYVYQKAYLELLVSPDVFPELISRIDKHP
DLTYYAVTRAGNFRTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGMDW
ARCFDAGTPSRILLERMMGEWYLVNIVNNDFHQPRTIFEVMTGLQVKDLDVEVQPDGPTA
N
>F8DK43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis (strain ATCC 15912 / DSM 6778 / CIP 104372 / LMG 14537)|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLTKEKVADTLQELNEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDIPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQPNFEVN
>B8CZI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562)|TrEMBL
MSREERVELDFSRVLTEREFIVTAELDPPRGVNTEDVVEKVKYLSDYVDAINFTDSPMAR
MKMNPVALTHHLKNKFNFKVDFICHLTGRDRNLIGLQSELLGGALLGVKNYLFLTGDKPE
YGDHPSSTGVFDCDGTALVKLANQLNGGRDYAGNPLNGPLDITIGAGINPGGNLTVEIEK
LKSRIGSGARFIQTQIVYDPGVVINFMERIKTIEALWPVKPRILFGIMPLKNYKMATYIH
ENVPGVDIPAPVMKAIKKGDERTGIKLAKEFVLNIKDYVDGIHIMPMGRMEVVSELVDAI
LTEGNRAIL
>Q4JWA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium jeikeium (strain K411)|TrEMBL
MASIRRQVAVSQSLSLNTPGRVPFSVEFMPPRDDAAEERLWNAAEAFHDLGVSFASVTYG
AGGSTRERTLRVAERLGTKPLTTLVHMTLVQHTQEELQDMLRTYASLGLTNLLALRGDPP
GDPNAEWVPTPGGLSYASELIELIREMPECADFDIGIASFPEGHYRTGSLEQDTEYTLAK
LRAGAQYSITQMFFDVDHYLRLRDRLAKADPEHGQKPIIPGLMPITSLRSVRRQMELAGA
ALPPKLEKRLLDAAAGDEVANRDAIREVGIEVTTEMAERLIAEGVPDLHFMTMNNVRATQ
EVLHNLGMAPAWGPGLGHDMVR
>Q65UG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mannheimia succiniciproducens (strain MBEL55E)|TrEMBL
MSYAKDIDTLNQHVADLNGQINVSFEFFPPKNEKMEETLWSSIHRLKTLNPKFVSVTYGA
NSGERERTHSVVKNIKQKTGLEAAPHLTGIDATPEQLKEIAQDYWNNGIRRIVALRGDIP
AGYTKTPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDNYLRFRDRCASIGIDAEIVPGILPVTNFKQLQRMAALTNVKIPNWLAVNYEGL
DEDQTTRNLVAASVALDMVRVLSREGVKDFHFYTLNRSELTYAICHILGVRPK
>G8JR06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582)|TrEMBL
MRISQKLQQLCEQQQTDENGVRRPSFSFEFFVPKTAQGVQNLYDLMDKMYQSQPEFINIT
WNAGGRKSQLTTELVSTSQSVLGLETCMHLTCTNMPCELIDEALKQAYESGCQNILALRG
DPPIVGDTWAPCERGFRYAKDLVLYIREKYGDHFDIGVAGHPEGYEEDEDPQQVLRNLKE
KVDAGANFIVTQMFYDVDNFIDWCRKVREVGINVPIIPGIMPITSYSSFLRRAKWCQIHI
PQMFYEKLEPVKDNDQAVREIGTKIMADICQKLLDSGYVTHLHMYTMNLEHASLMILDRL
GVLPFEYGAEKSARRGSIEALPWRKSLNPNRRNESVRPIFWQRRPYSYVARTAMWSADEF
PNGRFGDSSSPAYGDLDLCGRTLLRQTYERSLILWGQPKTLQDLAHLLITYLKGNIKCLP
WSDVPLSREVDEILDSLLTLNSNLIFTINSQPKVNGVPSTHLLFGWGPADGYVYQKQYLE
FLLPKNKLEAFHQDINANYPTLTYFSVDVHDMLATNHPDESKANAVTWGVFAGREVLQPT
VVEKSSFLAWKEEFYRILLDWKLSFQENNALESAELLQTVIEDYALINIVDNDFVTKEDR
IYQLLSKLF
>A0A3D6DQ60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter sp|TrEMBL
IVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLASIRAFGLDVVTDLCDRLLA
GGAPGLHFYTMNQAGPSTTIWQRLGL
>A0A830G824|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halarchaeum nitratireducens|TrEMBL
MAQTTSTSRDSTTLLADPRYELMPFDTFGDQIEHLPDGATVTITASPQLGIERTIEAAEE
AAEQGFEVVPHVSARYVRGDDHLAEIAEQLTEIGVDDIFVPGGDREEPIGDYESAYDLLQ
GLERIDYDFEEIGITGYPEGHDFLSDETLAESMDNKAPYATYIATQLCFDPNAVLEWIEE
IRARGVDLPVVVGIPGVMKYSRLLSISRKVGVGDSIRFLQKTNGILGFLRQFIGSRGNYT
PDALIDGLQPHADDPEYNIQSLHIYTFNQVPDTESWRKSRLGE
>A0A6A8M7E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. WCA1-178-WT-3|TrEMBL
MRVDEVFKQAASQGTTPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPASAN
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACENLNLSVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMTFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A7H0G9T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sediminicola|TrEMBL
MNRHLPDEVGGKPLFSEARGDIQVSFEFFPPKTEKMAETLWDSVQTLAPLHPRFVSVTYG
AGGSTRERTHQTVERILKETDLTPAAHLTCVAASKAEIDEIARDYWDLGVRNIVALRGDP
PEAGTKYQPHPEGYRDACELVAGLKAVAPFDISVAAYPEIHPDSRDRTFDLENLKKKVDA
GADRAITQFFFSADCFFRFRDEAAAAGIDVEIVPGILPVSNVATTRRFAASCGAAIPKWL
DDLFEGLDDLPAARQLIAATVAAELCGQLYAGGVRHFHFYTLNRAELSYAICHLLGVRAQ
A
>A0A6A2WI38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hibiscus syriacus|TrEMBL
MKVIEKIQSLQQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVRHIRAKYGDYFGITVAGYPEAHPDAIGDNGVATPEVYQNDIAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMTGFCKT
KIPDEVTAALEPIKDNDEAVKAYGIHLGTEMCRKIIANGIKTLHIYTLNMEKPALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPQGRWGDSQN
PSYGVLSDHQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSYCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSREKL
DALVKKSESFSSLTYVAVNKDGNLVLNIGLTSVNAVTWGVFPAREIIQPTVVDPASFVVW
KDEAFEIWARSWSALYPDGDPSKKLLEQIQKSYYLVSLVDNNYMDSNIFGVFEDL
>A0A0D5XYA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas chlororaphis|TrEMBL
MTLLNKALSEQTFVCILEFVPKPDARRFAAVEALMARSQLCGWPLTLAIADRVGNPLEMS
PLEAFRSLGQPVPALLHFSGKDRERQDLLAQLPRMDAAGVQQLLLLTGDRLPGQRPVRYL
ESVAALQSVRQARPHWWLAAALNPFKYREEEGGAQYFKAEKKLAAGADCFMLQLGFDAQK
HLEAIAWMNRQPNPKPLIACILALTQGRARMLDQVAGVVVTPSMRALVDAEAAVSKHYAR
ERSIERLALQAIGLKLMGYAGINLSGIHDLDQLLALEQAINAWQPRVPSLEQWRAAWDAA
WRMPGLGPVSFHPAEANWRLGESRVGASPREQARYHLLHGMHSLLFDRSTWTSRAFGWAM
RRPVWSSATGARWLHRLERGLKRPLLGCDTCGSCRLEDTLYICPETCPKGLANGPCGGTS
LNRCEFGDRECIHSVKYRTAKAVGQSAVLSQRLIPCVEVGNRHRSSWPRWFDNPPSTAQA
PRHERDNAGTVAVSKD
>A0A1R3X0G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yoonia rosea|TrEMBL
MSKPNVSFEFFPPKSLEGSFRLWDCVNTLAPLDPTFVSVTYGAGGTTRKLTHEAVTTIHK
TSGLNVAAHLTCVDATRAETLQIAEDYAAAGVREIVALRGDAPKGAAKFTAHPEGFDSSV
ALIEALANTGQFTIRVGAYPEKHPEATDHAADIAFLKRKFDAGATSAITQFFFEAETFFR
FRDACVKAGIDGQIIPGILPVENWNGTQRFAKQCGTHIPQVIHDAFENATRDGSTELLAT
AVATELCDDLLQGGVDHLHFYTLNRPELSRDVCHALGVTPKVRLQNVA
>A0A238FEZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbotryum intermedium|TrEMBL
MKQLGPIFVDITWGAGGATSEATTTFVKHAHSELGLETCMHLTCTNMPVSMVDAALKEAY
DSGCRNILALRGDPPRGSEEWVQTEGGFNHAIDLIRHIRKLYGDYFDIGVAGFPEGHPQA
ESPELEMKHFKAKIDAGANVIFTQMFYDANVFINWGRRVREAGITVPIVPGIMPIQTFAS
FKRRTDFAKTIVPQELWDLLEPIKDDDLKVREVGTKFVADMCRKVLTAGIGINGIHCYTM
NLSRGTEMLLEEMNFVAQADIVKPLPWRVSLTQKRRTETTRPIFWSNRTRSYLSRTADWD
EFPNGRWGNQASPAFGDLDSLALSLPHKAQDATTLWGEPTSFEDIAQLFARFCAGDLKAL
PWSDQPVAKETTVISEPLKKINLAGFLTINSQPRVDGASSSDPVHGWGPRGGYVYQKVRQ
FLRSVLAYLEFFASPAHLDDLLKALQKYPSMTYYAVNKAGELQTNAAAGPNAVTWGVFPS
AEVIQPTVVDGTAFLAWKDEAFELGALWAELYQKTREDSANVISDIFDTFYLVNLVQNDY
RDEDELAIFKPFFEVIDDSKIALNGVNGSH
>S0G3I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotignum phosphitoxidans DSM 13687|TrEMBL
MENNDMKSAGNFEKILRAGHFAFTGELGPPRGANVDIIKKKAAPLKGMVDAVNITDNQRA
MVRMSSWATALVVMNEGIEPVYQMVCRDRNRLAMQSDVTGAYALGLRNMLCISGDHQQFG
DHPNAKGVFDIDSMQLIAMIKKMRDEGKFLGGADIDTPPKMFIGAAANPFAEPFEWRIHR
LAKKMAAGADFVQTQCVYNMKKMREWIKQANDMGLSEKVYILAGVTPMKNIAMAKYMKAK
VPGMEVPDEIIRRLQGVKRNQVADEGIKIACEQIEEFKETKGVAGVHLMAIEWEHRVPEI
AERANVLPRPKV
>A3YX53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. WH 5701|TrEMBL
MLLRQALETGQFAITAEVTPPRGGDPSRTLAVAAKLRGLVHAVNVTDGSRAVMRMSSLAL
CRLLLDAGIEPVLQLACRDRNRIALQADLLGAHALGIRNVLCLTGDPVGAGDQPGARAVN
ELEAVRLLQLLGRLNAGLDPVEGVLPDGPTALFPGAAADPQSPSWSGLRARVARKQAAGA
RFLQTQMVMNTEALRRFCGEISEPLGLPVLAGVFLLKSARNAAFINRVVPGASIPQPIID
RLAASADPAAEGVAIAAEQVRSYRAIAQGVHLMAVKAEERIPWILAEAGVSPPGGSLLTE
VSSRPH
>A0A0P1A754|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plasmopara halstedii|TrEMBL
MGKIIESIRNAYAARADDTSTRPTISFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTIT
WRSAFKDEALWLRIGAHIQNNFQIDVLLHLTCHLPTEKLKCILKNARAAGIRNILALRGD
PPIGAERWTPIEGGLSNAIDLIKLIRKEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQEAGAEFIITQFFFDVDNMIQWIADCKNAGITIPILPGYLPIQNYSSFCK
FTKWCKTQVPDNVLTALDAIKNDDAAVRRYGTQLAVETCQRLLVAGVNSLHFYTMNLAAT
VTQVLEGLQLLPARNQRDLPWQSTLQRSTVEHEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKVQRTELWGTPQTVEDVWNVFVRFIEGHVKQLPWCEQ
ALSLESTAIRENLRWLNSKGFLTINSQPRVNGALSSDQSVGWGGNDGVVFQKAYVEFFVA
PEKMAHLVNVMQRDYPQLSFHALNRQGDEHRNTPLHSVTAVTWGVFPVSHDHGGSWTRAR
NDDHEQAAQDE
>A0A095SXI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium aquatile LMG 4008 = ATCC 11947|TrEMBL
MKVTEHIENANGKSLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPSGLLQKKIVKKRPGTVGICAGIQNKYDVDAIPHILCGGFTKEDTENLLIDLDFLGINN
VVALRGDALKNETYFRPEREGNEFATDLVLQIDNLNKGIYLDEDLQNSACTNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNKKFFDYVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMAVVKAKDNDAVKQIGIEWCTQQSKELVAAGIPVLH
YYSMGKAENIKAIAKDVF
>A0A165FZ12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Laetiporus sulphureus 93-53|TrEMBL
MKLNQKIAEYREIHPFFTFEFFPPKTDQGFDNLLSRISRLVSLNPLAVSITWGAGGSTKD
RSLELAGLTQSEHGVDTILHLTCTNMKQGMVDEALRDAKARGIQSILALRGDPPRGEEYW
ISTDPRFNHGADLVSYIKSSPEFSSDFCIGVAVYPDGHPDRGTDEEGELEHLKQKVNAGA
DFIITQLFYDVDGFLQWVKKVRQKGIQIPIIPGIMPIQTYASFLRMTKLCGTRVPPSLMS
DIVPLRHDDQKVKDYGVGLAIKMIRQLTADGDIRGVHFCTLNLEKSVTRVLEGLGWAGGS
PKPANKLIADDVAGPGSELVVTPHNATDTAAKELAVSSPGPDGEAGKGELNNAASWDDFP
NGRFGDFKSPAYGETDLWGSSIMSHKQAIKQWGDPTTLDDLTTMFLRYLHSKIATTPFSP
SPLSPESLMIIHHLERLTRKGWWTVGSQPAINGASSSDEVVGWGPRGGYVYQKCFVEFFV
EGADLEKIERKVKEHGHGWVDYYAGNVQGECHTTVPEGGRNAVTWGVFPGQEIAQTTIIE
KESFLAWKDEAFSIWAEWASFYPPDSHERTQLESIRNERWLVSIIHHDYMDPSSLWNFLF
KDDPLV
>A0A2S5Y1H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter rathayi|TrEMBL
MSEQRSESDPACPRVPFSFEVYPPRTAAGSLALTRTVDRLAAAGPSFVSVTYGAQGSSRS
ASLGILRYLLERTATPALAHITCVGSTHAEASRLVREFLEAGVTRFLALRGDRPTGIPED
AAILGELASAAELVQLIHRVQAEREPYGAMPVPGLRNAQCVDVAARPHAEVAVAAFPNGH
PRSRSRTQDIDVLLAKEAAGASFALTQLFFHADDYLRFVDRARAAGLRMPIIPGVMPVTS
PARLRRMLELSGEDLPADLAIALDVEPDDEARMRIGVEYAAKLIRTVVDGGAPAVHLYAF
NRDEAVLAVLAESGLLPPGSAPTLPTATSPSTPSPQERTA
>A0A5J5E9K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium reuteri|TrEMBL
MHTPMFSLEVFPPKRNAPVGTIYDTLDGLEGLEPDFISVTYGHGTHTDRTATARIANTIR
NEYGIPAVAHLTALYSDRNKVDEALDMFEQAGVQAVLALRGDYIEGEEPVAVFEHASDLV
AYIRERKPEIKVFGACYPEGHYQSSSLDEDIANLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGAKSVRRMAERNASRIPDHLAVMLDRWEGDAEAMRAAGIA
YASEQITDLVAHGVDGIHLYSMNHPATTRRIWRNVQPLFGE
>A0A6I3XCP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDQLLAAGATRSFEFFPPKNDAESAILADTIRDLRSLDPSFVSVTYRGGRESRQRTFD
LVHSIETEGHITAMAHLICVGHGRDEMRDILQNYVDGGVENIMALGGDIPVDPALQGGEF
THALELVELAREVGSFSIGVAAHPLGHPRSDDLVSDRKHLATKLREADFAVTQFFFDFEE
WRRLVNELGSLGVTKPVLPGIMPVTTLSGVTRMADMGAAVPIWLVERLERAHEQGGSPAV
RTEGIRAATELCRELLDGGAPGLHFYTLNRSTATQEIHSQLFG
>A0A7V4MYB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGWSLDRFKGVKLRAAKALGINRVTLDRKIVEHGLTVQRGKGLVEAVAAGRFAVTAECGP
PKSADGTVIAEKTKLLRGFVDAVNITDNQTAVVRVCSLASAVTAQQHGVEAIMQMTCRDR
NRLAMQADILGAATLGIKNVLCLTGDHISFGNHPQARGVHDLDSLNLLKMYKDMRDEKKF
QCGEEMAVAPALYIGCAENPFGDPFELRALRLKRKIEAGADFVQTQCIFNLPKFKRWMEE
VRALGLHQEVKILAGLTPIKSAGMANYMKKSVPGMDVPQEIVDRIAAQEKGPPQQAEGKR
LAVEMIKELAEIEGVAGVHIMAVEWEPAVPEIVEAAGLLPRPATA
>A0A7W0PFX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MIPLPGAEEAVLEHVPTDVKVTVTTSPKKGLEPTVELGERLAGHGYSVVPHLAARHIRDR
GHLAELIERIRASGANDVLVMAGDATQPAGEFDGSVPLLRALAELGKPFSDVGITGYPES
HAFLSDEATIRSMFEKEEFATYIVSQICFDPHMTASWAAAVWQRGTRLPIHIGLPGAVPR
SKLLRVSERIGVGNSIRVLRDHEGRLERTLRDDFDPDPLVVGLQESLGQPRPNVAGFHIF
TFNALADTERWRQHALAHATRSS
>A0A538BQ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTVGRLEWTGDGKLRREGWDTARMDAAVFRSLLAEAPLLADGGMGTSLIARGVPVDACME
ELNVRAPTRVAEIHASFVGAGARLVLTNTFGANRYRLERHGLADRFAELCVAGVALARDA
GAPIVAGSMGPLGIRLQPYGRVHPEDAFAAYREQAAALADAGVDLLIVETQSDLRELEQG
VLGARDAAPDVALIASATFTRDDRTLLGSPPEEVAQTVVALGVDALGVNCGEGPAQVLRI
VRAMRRTAAGAGVPIVARPNAGGPAEVGGRFVYPATPEYFGEIARALLDEGVAVIGGCCG
TGPAHTTAIGTALHDRAPHVRIEFPEADHGERILDVVTVAPPTKLEAKLATGHFVVTVEM
EPPRSFNAARLVAAAETLRDAGADAIDVADSPMAKMRMSAWAACRLIHEQADIETVLHFP
TRGRNLLRLQGDLLGAYALGIRNLFVCVGDPVTIGEYPHGSNNVDVTATGLLSMITHAFN
AGVDRSGTSIGAPTSFFAGAAVAPSAPDLEREARLLARKAEAGARFVLTQPFYSIDPLLA
LRETYEKVAGEPLTVPVIAGVLPLMMSRHAEFLHNEVPGIEIPEAARDRMRSAGDDDDRA
WEEGAAMAIELIAALREEGVAGVYVMPQFGRYDRAAEVVEAARGPATM
>A0A6I2WMF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MEIRSAKSGDNTKVTYSFEFFPPKDPEGEERLWQAMSQLESIAPDFISVTYGAGGSTRDR
TIRITSEITARTHIPTVAHLTCVGSTREELIDILGKYRDAGIKSILALRGDPTGGPRARW
SPTAGGFNHADELVTLAAEFGGFTIGVAAFPDGHPASNGDFDKDVDVLIEKERRGATFAT
TQFFFEFDKWKKLVDKLEAKGSALPIIPGILPVTNVKQLNRMAELSGTPIPAHISDSFSK
VEGNTEDVRKLGVEIATKLCQELLDAGAPGLHFYTMNTSSATREIYSHIKDER
>A0A7W0UHB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSSKLPEDLEVRPGKAEALKRLLGRPDFEIFPSASVWEHTEDLPPRAKVAVTCSPSRGIE
ATLALIEHLTNQGFAVLPHISSRLVTDRAHLQGIINRLEGLAVFDIFVIGGDVDQPVGPF
PSALSLLTAMAEVGHHFSEIGVAAYPERHPFVDDDTLWRHLHRKQAVASYMTTQMCFDAT
AILRWIEEARRRGIGLPVRVGLPGVLNRNKLLKTSMRIGVGDSARFVRKHTGLLTKLIGP
GRYSPDDLVASLAEFVDVRPYDLRGLHIYTFNEIADTERWRRAVLTSLEQ
>A0A1M6LJB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paramaledivibacter caminithermalis DSM 15212|TrEMBL
MLIRDKFKNKNPLISFEIFPPKKDYPVDTIYGTVDALNDLRPDFISVTYGAGGSTKDTTV
DIASFIKNKYDLSALAHLTCLTSTKDEVEETLNSLKGKGVRNILALRGDYPEGAGADYIG
PNHYKYAKDLIAHIKENDDFCIGAACYPEKHLECQSLDKDLLHLKEKVDAGVDFLITQLF
FDNETFYSFKEKADKLGINVPIIAGILPVLNKNQVEKIISLTGCTLPKKFLRVLEKYEHK
PEALREAGIAYAIAQIIDLLSWGVDGIHVYTMNRPKTTRRIIESITNIRGVLANEEAS
>A0A7K0Q945|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSLLREKLENSNERVFTAEFPSIDGGGMVSVEKNVARLAPWFDAVNATDNPAAHAHASNT
TTAIAMKMFDLEPIMQIVCRDKNRLAIQSDMMGASLHGITNISLLTGDDVTAGDEPEARR
VFDIDSAQAINIARIMTTGQYLSGRKINPAPDFYIGAVENAAAPPFDYRIQRALKKHRAG
ARFLQLQICYHPDRLEAFCRGVAEVAPDLKLIPTVVLMKGAKGLSFMNDKVPGIDVPVDT
LKRVQSASDPSVEVNKLTLELAQHALTLPGVRGLHITDFRHDDTLAIFMNDLGRTP
>A0A7V9QX56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTDAAPVSRISVELVPRSVHSVQADVAAVDQHLPHVDTINVPDLTKFSLRSWDACALARQ
VPRSGGQAAYEAIPHLRSQDLNPDTALPMARALEESGIQEVLIVTGDVPNNFSGATYDVD
AVDAIRRLRADLPHLSVYAGLDPYRHSLIEEAEYAERKLEAGAGGFFTQPFFDMSLMHAW
GGLLPTDVPVWWGATTVTSPGSHNYWRRRNRAVFPAGFETTLDWHRDFARRAVAFARERG
QHIYLMPVAVDVRSYLEGIV
>A0A6I3DSQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARIGDLLATGRTFSFEFSPPKSAAGSLSLGRTIAELEPLAPSFVSVTYGAGGSTREHTR
DTVLWVRKETNIPPMAHLTCVGHTRAEIADIISTYTDAGIVNVLALAGDAPKDPADARPS
DYVYAIDLIEHLKEIGDLCIGVAAHPEGHPRSPDLATDRQHLADKLRAADFATTQFFFDL
DHYLSLVNDLADLGVTKPVVPGIMPVTNIAQVERMAELSGAAFPAWLRERLESGTSPEDV
RRIGVEAATELSAQLLEAGAPGLHFYTMNKSTATLEIYAQLGLPVV
>A0A537X831|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDEIIAGSSEPVFSFEFFPPKTAEGERNLFAALQELSKLDPAFVSVTYGAGGSTRTKT
IEIVKRLRDEFGLEAMAHFTCVGATVEQLRGTLDEMRDAGIDNVLALRGDPPAGQEQWRK
TEGGLEFSRELIEMLDAGYGFAIGAACFPETHLDAVDAESDLRYAKAKVGAGAGFLITQL
FFDNAFYYDFVGRARAIGIEVPIIPGIMPIANFQQIKKFTSMCGASIPPALMAELEARAD
SPQAVSELGLSYATLQCADLLAHGAPGIHFYTLNRSPATRAILSALRLMRPWDRRRLASA
RTPAPPPWPAGARRPARPHVPGSRCPAPGARR
>A0A502XY93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-6-5|TrEMBL
MNQFRFSRRPGIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHQVDAVIQEFTDMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVA
GSAAA
>A0A4Y4CVA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zoogloea ramigera|TrEMBL
MTSSLPTPHPSQHLSIEFFPPQTAEGADKLRVVRQKLAVLKPEFFSVTFGAGGTTQERTF
EAVFEIQREGHQAAPHLSCIGSTREHIREILQRYQAAGIRRIVALRGDLPSGVGFAGELR
YANELVEFIRAETGDHFQIEVAAYPEYHPQARTPRDDLLAFKRKVDAGADSAITQYFYNL
DAYLHFRDECAALGITIPIVPGIMPIVSFSKLARFSDACGAEIPRWMRRKFEAYGDDTDS
IKAFGLDVVSELCAKLLAAGAPGLHFYSMNQAAPTLAVCERLGILA
>A0A136QJU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas monteilii|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLQLPR
>A0A537ZS42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSRLEEAIAEGRFVVTAELLTIDAGGLDAVRERFEPFEPWVDAVNATDNTSAHAHASPVA
VAIALKQLGVEPVMQLVCRDRNRLALEADIAGAALHGIENLCCLTGDDVTAGDEPEARRV
FDLDSSQLIATAAAMARGHYLSGRKIDPAPHLFIGAVENPAAPPFDYRVERALEKVRAGA
RFFQLQVCFHRELLERFIAEAVASGLADKAALIPSICLVRSPRSLRFIDEHVPGISVPPE
MIERCEHASDSEAECFELGCELAEHARSLPGIAGLHLISFRREAGIARLCTRLAIPTRAE
RETRGYRSPVAV
>A0A446C2M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter agilis|TrEMBL
MSDSTTPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGATRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYASE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVRKVRAGADAAITQYFFNADAYF
DFVDRAQAKGVEVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPMAVWKELSLQA
>A0A538DZU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
GGCCGTTPAEIAAIDEALAGERKPRARLEFAERELLVSLGEELLETGLARALREREWVVT
IQLDPPLGGSSKGLVELAHAIGESGKAGYVDINDNATARAGMSSLIVSATIERQAGIETI
PHLTTRDASVMGLESMLLGAHSEGVRNILAITGDPPEVGDYPGAQGVYEIDSVGLTELMT
RLNRGEDFNGRPIDAPTSFFPGVAVNPTPDDLELELERFHAKVEAGARFAITQIVFDLDY
FDRLTERLGGSWPIPVLVEIFPLTSYRLALRLHNEVPGIVVPEALQLELQNAGANAAEVG
CSRARELIEGARERAAGVCLVAPFRQPLRVLELLE
>A0A1Q6EJY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium 52_46|TrEMBL
MNIPQIIESTPGRGFSFEVLPPLKGKSIETLFRGIDKLIEFNPRYINITTHRSELVFKQT
DGGLYQRVAQRARPGTVAVAAAIQNRYKIPVVPHIICSGFSKMETEYALIDLSFLGITNV
LVLRGDKAKHDSKYTPNENGYLHATELQQQINEFNKGYFIDGTSMDTGRGTPFSCGVAGY
PEKHEEAPNFDMDLQFLKAKVDNGADYIVTQLFFDNAKYFNFVERCRAIGINVPIIPGIK
PITNINQLSVLPKIFKVDIPSELTGRLMACTTDEERKAAGIEWGIRQVNELYEAGAPSIH
YYSLNAVDSVREIVRNTL
>A0A369QZ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum sp. 12E13|TrEMBL
MSSAPSVSFEFFPPKSVEASFRLFDTVQHLAPLGPRFVSVTYGAGGTTRKLTHEAVEALV
KTTDLTVAAHLTCVEATREETLEIAKGYAEAGVKEIVALRGDPPKGAERFTPHPDGFADS
AELVAALKEVSDFTVRVGAYPDPHPDAGYDDADVDWLKRKFDAGADEAVTQFFFEAETFF
RFRDKCAKAGIDKPILPGVLPIENWKSARRFAVKCGAYIPAWLDEAFEKAERDGDGRTDL
LATSIATELCTELREGGVEHFHFYTLNKPGLTRDVCHALGVTPDMQLEKVA
>A0A2E1CBG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKSTQLKLLDGMTYELIPLKNVHEQGEYLPKSSTISITCSPAKDIEATLELCESFLSKGH
TTIPHFAARMVESEEHVAQIVKRIESLGIETVFIIGGDADQRGPFNDAPGLLRSFLDKNP
KIKTVGIGSYPDGHPSIPESALAESLIKKQEMIYESNLNGYMATQMCFEAKTISSWLKNC
REAGVTLPCHLGLPGVVDMKKLINISLRLGVGVSSRYLKKNRKSVFKLLSPRGYNPNKLI
VPVSDYAEELDIAGIHCFTFNAVESTEAWRTKTMERLT
>A0A3N5K1Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARIADQLAAGRTYSFEFSPPGTEAGWMTLGRTIAELDYLNPSFVSVTYGAGGGTRVRTH
EAVAWIRKETPVTPMAHLTCVSHTRAQITEILDAYDSVGVENILALAGDPPSDPTKAGPS
EYGFALDLVEHVREHGTFSVGVAAHPEVHPRSTDPEADRDHLAAKLRVADFAITQFFFEV
EPYLRLVDDLAARQVDKPVIPGIMPITNIASVARMAQLSGAAIPNWLTDRLEAVADDPDA
VRKVGVDTATELARQLLDRGAPGLHFYTLNRSTATREIYANLGLAP
>A0A4P5QYX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNSVPTFSVEFFPPKDQAGEERLWSALKALAVYKPDFVSVTYGAGGSTRDRTVRITSEIT
ARSGISTIAHLTCVGSSKDELIEILNQYKASGIKSILALRGDPKGGPGVKWESTAGGFDH
ADQLVTLASSMGFEVGVAAFPDGHPASMGNFEQDIKVLLEKERCGASFATTQFFFDVKGY
INLVDEIRARGSKLDIYPGILPITNFAQLKKMSELAGSPIPSEIKRRVEAAGDTPADVVK
VGVDIASELSKKLLDYGVPGLHFYTMNSAAPTIEIIKRIGLR
>M1VXE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Claviceps purpurea (strain 20.1)|TrEMBL
MEKITDKIAALPADGEYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
ATKSMELAELCQRELGLTTCLHLTCTNMSKRLIDKTLEDAKVLGVRNILALRGDPPRKEE
YRTEDDSETDGDGDDFTWAKDLVRHIRKKHGDYFCIGVAAYPEGHSDESHPVGQSLQHDL
PYLVDKVQTGADFIMTQLFFDIDAYDEFEKTLRDHPSGAFKTIPIIPGLMPVQSYQMIKR
TTKLSHAKMPSAIMDRLNAVQGDDEKVKLVGVDIISELIDQIRTIKNRSPGPKGFHFYTL
NLEKAVSFIVERTGLIPDDENKKEEAVMDGTSSPLATNPTSPPSLQVNGNLISSNSRRSS
RRRSSFGSDPYNRVIVGGRPVTRPDWETSGQEAGVPADSLNSRANTLAISEGEGVLGREA
TWDDFPNGRFGDARSPAYGEIDGYGVSLHMSGTQAVNLWGRPKTIADVKDLFVQHIKGDV
PAIPWSEEGLSAESSTIQDRLLGMNARGWLTVASQPAVNGISSSDRTFGWGPANGFVFQK
AFAEFFLPSADWHVLADKLKGSDYCDSVCFYAANAAGDFMSSDMSSGSGVSPARDVATAS
TNAVTWGVFPGKEIVTPTIIEEVSFKAWSEEAFGIWGEWAKVYGRGSESEKFLSGIRADY
WLVNIIHHDFVDGEALWMLLLG
>A0A538ICC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSRFEERLGSETPIVADGGMGALLSSAVPGLRCPEEANLRAPESVLEVHLGYIRAGAELI
ETNSFGANRAKLARQFLGEELEQINAAAVRIAREAREVAGRDVFIAGSIGPLGDVELAGV
DPGELFAEQARILEGRGVDLFMVETFYDLDELEAAIGAIRSVSALPLVALMTFDAQGETL
AGVRAEDAAARLRPLGLAAYGANHGAGPAAALAALARMGGDGAVLAALPNVGLASMTGQR
IVFPHATPAYFAEFAAQARALGARLIGGCCGTTPAQVTAIREAVDANRSPAGSFLVHERK
QAIPFQPATGETQLARLLRKGEFAISVQVDPPLGANPQALIETARAVRDSGRAQFVDVND
NPRARARMSGLMASVAIERFTGVETIPHLTPRDSTITGLESLLLGAHAEGVRNILAVTGD
PPEAGDYPGTHAVYDVDSIGLVELIAKLNAGEDWHGRAIDAPTTFFPGVAVNPTADDLGL
EAERFHRKVAAGARYALTQILFDLEALDAFRERIGGWPIPVLVGVWPIRTTETLVRVHNE
VPGIVVPDHVQERYRTAGPGAREVGLALGRELIEGARELASGVYVVAPFRRPLDVVELLP
EES
>A0A162QFA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor lusitanicus CBS 277.49|TrEMBL
MKVIDKIHKAEQEGRPFWSFEYFPPKTPQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
DLTTEIVATAQSVYGLETMMHLTCTNMPVKQIDDALEAAKNCGCQNILALRGDPPKGQAN
WESCKEGFEHADDLVRYIREKYDDYFCIAVAGHPEGHIDNPDKEDDLLQLKKKVDAGADL
VVTQLFFDIDSFLTFYKKARAIGITVPILPGVFPIQNYTGLKRVISFNNNFVPQKIWDDL
EPIKDDDTAVKEYGINLTVEFIKKFREIGVNGFHIYTFNLERSSRIVLERLNLMAPVESI
KPLPWNPSLTSKRAKENVRPIFWKNRAKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
INLKYPVDQCLEMWGSPTSIDDVAQTFARYCKGQIAGIPWSAQQLDAETDIIRQRLAAIN
LLGYLSINSQPAVNGVKSSHSVYGWGPKNGYVFQKAYLEFFVSPEKLDELIEKIGKDPQV
TYYAVNKQGDLRTNTQSDEPNAVTWGVFPGKEIVQPTIVEAVAFMAWKDEAFELWNRWAR
IYERESESAELILDITKNWYLINIVHNDFQDENGIWRLFDLEIDVFNYL
>A0A1F9LUY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYD12_FULL_57_12|TrEMBL
MNIRKNSRLFHALNDPETFALTFELVPGRGGQTREINRILALAREIAADGRFHAVSITEN
AGGHPALSPEVLGKEIQAMGPDVIIHFSCKDKNRNQMESLLFSWDRQELHNLLVIAGDYP
KVGFRGHPKPVFDLDTIQALDLLTAMNRADDDRTAAEGGSQAGRSASFLKGVAVSPFKLL
EAELVMQYYKLHRKVAAGADFVITQLGFDGRKFHELLLYMRQNQLNIPVLGNVFIPTLPV
VELMYQGKLPGCVIPEALYEQFQWEARTADRGRKARLLRAARLLAVLKGLGYAGAHIGGP
GLSFADLDFVLQQAEDFSSHWQECLAELTFWPRDAFYYYEKDAETGLNRPEPATRPRPVS
AGLAYFLASRVHDLAFEPMGQLYEPAKKICLAMEAGRLHGLLDRFEYLVKVVLFSCQNCG
DCTLADLAFLCPQSGCAKYLLNGPCGGSRDGWCEVYPGKKRCLYVQVYERLKAIGRDQGM
AVGFVPPRNWGLNNTSSWVNYFSGLDHTAAENEAE
>A0A846D2I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO2C4|TrEMBL
MTNPTNNSFRTAVESGEFLITAEVAPPKGGNAAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILHQQGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFER
KLEAGAQFFQSQLICDFDRLEKFMVQIAAGTNKPILAGIFLLKSAKNAKFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLARQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSPVNDLVFK
>A0A352BMS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPGTIEHLMKYKPEYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLEQYLAEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A179RZ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium platani|TrEMBL
MYPTAFRPSRDSRRPIRVSFEFFPPKTAEMEATLWSSIERLAPLGPSFVSVTYGAGGSTR
ERTHNTVSRLVRETDLKPAAHLTCVAATRGEVDEVVRAYHEAGVRHIVALRGDPAEGVGT
AYTAHPGGYERSCDLVAGIKRIGDFEVSVSAYPERHPEAGSLDQDLDALKAKVDCGADRA
ITQFFFDNDLFFRYLDRVQARGIDIPIIPGILPVQNFKQAANFARRTGASVPDWLAARFE
GLDDDVATRKLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRAASPAAE
KAAA
>A0A1Q4X0V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis sp. TSRI0078|TrEMBL
MAPRSPAPRPRHIRELLDAGEPMFSFEFFPPRTPQAQERLWRAIREIEALGPSFVSVTYG
AGGSTRGMTVETTERIATDTTLLPVAHMTLVDHSVAELRHLVGRLADAGVSNMLAVRGDP
PGDPSGEWVTHPQGLTYAEELVRLIKDSGDFCVGVAAFPFKHPRSADVETDTDYFVRKCE
AGADYAITQMFFDPEDYLRLRDRVAARGCEVPIIPEVFPVVRTSFIPRSEQLSGAPFPRH
LAERFESFGDDAEAVRAFGIEYAQRMCERLLAEGAPGIHFITSNQSTATRQIYQEIAGHR
SRSEAAGRP
>A0A3A0FER6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MKTPGTISFEFFPPNTPPGVEKLRGVREALARFDPAFYSVTYGAGGVTRDKTLSTVLEIV
GERRPVAPHLSCVGASRESVRELLALYRAHGIRRLVLLRGDLPSGMRGSGDFRYASDLVA
FVRAETGDSFHLEVAAYPETHPQARTPRDDLRAFAAKMRAGADSAITQYFFNADAYLRFR
DAAARIGVDAPIVPGIMPISNFSQLARFSDSCGAEIPRWIRLELAACGDDIEAIRAFGAE
VVAAMCRRLLAEGAPGLHFYTLNQAGPTSAILDALVAPR
>A0A140KZT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidicola ferrireducens|TrEMBL
MGLKEKLESGGFAVTAELAPPKGTDTTRLVECAKAIKGRVDAVNLTDFQSAVVRVSSLGA
AILIKQQGLEPVMQITGRDRNRIAIQGELLSAAAVGIKNILALTGDHPVFGDNKQAKPVF
ELDSVNILETATCLMQGKDLAGNPLNGTPEFYLGASVTPHYDPIELQIIKMEKKIKAGAK
FFQTQAIYDIQDMKRLKEMTLHLDVKILAGIIPLKSAGMAEYMNKNVPGIYVPEHIIQKL
RNSQDKVKEGLKIAAELINQLKDGKLCDGVHIMAIGAEENVPLLLDMCGF
>A0A1F9LTT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYD12_FULL_57_12|TrEMBL
MLVKDILDANRISMSFEFFPPKVETEWDRLFKNISDLIPLAPAYVSVTYGAGGSTRDRTH
KLVVRLKQETDLTVVSHLTCVGSTRDETRSILENYAKHGVENILALRGDLPKGQKEWQQP
ADGFAYATDLVDFIKTQFPRMGVGVAGFPEGHPETQNRLKEIDFLKAKVDAGADYIVTQL
FFDNRDFYDFRERCELAGIHVPIIAGIMPITTRNGMVRMAELAAGARIPARLLKAMARTA
SDDYVEKVGVHWATEQVRDLIDHSVRGIHFYTLNSSRATLRIYESLGVRSSEQLAC
>M3FVQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Grippotyphosa str. LT2186|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A367XIJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira xiamenensis|TrEMBL
MTVKNDIAPQGTSHGDLRVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGST
RDRTHSSVTRIQGETGIPAAAHLTCVGHTKEEIEGIARNYWDEGIRSIVALRGDLPDAGD
KYVPTPGGYPYAVDLVEGLKRIADFDISVSAYPETHPDAPNADFEIDYLKHKIDAGANRA
ITQFFFDNEVFLRFRDKCAAAGITAPIVPGILPVTNFGSLLKFADMCGASVPKRLHWRFE
DLDEDPDTRRMVAFHEAISQVEGLMAEGVTDFHFYTLNRAELTYAICHALGIRGVAQAAA
>A0A2U8QSR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sediminis|TrEMBL
MKVTEHIKNANGKTLFSFEILPPLKGQNIQSIFDGIDPLMEFNPPFIDVTYHREEYEYKE
LPNGLLQKKIVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGHRYASELVEQIANLNKSVYLDEDLKNTTATDFCIGVAGY
PEKHMEAPSMDSDIHFLKQKIKNGADYIITQMFFDNQKFFDFVSKCRAEGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDCLIMEVVKAKDDEGVKQIGIEWSIEQSKQLIAAGTPVLH
YYSMGKAENIKRIASAVF
>A0A2B7WJA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicocarpus griseus UAMH5409|TrEMBL
MEKISDKIAALPQDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDDALSEAKVLGIRNILALRGDPPRSEE
YNIDGEDDSNKEFTHAVDLVKYIRRTHGDYFCIGVAAYPEGHSDESYPEAQDPARDLPYL
VEKTKAGADFIMTQLTYDLEAYKRFEEMLRNHVSGVFKTIPIIPGLMPIQSYHILTRTTK
LSHAKVPPDIMARVEEVKADDEAVKRIGVDILCELVNGIKKIPSPGPRGLHFYTLNLEKA
VAFTVERCNLIPALSEPSSDSDTDLDSAVFMAQGGAPNGVPLISKRRASSLNSQPHNRLI
VDRPSLVPDGSASSQASTSHETQALGAGMPALNPPHRTTALQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVNAAIARRLWGYPTSKEDINDIFQRHVSGELHIVPWS
EGGAEEESGGLNPETATIRDELLQLINGRSWWTLASQPAVNGVRSDHPVYGWGPPGEGFV
FQKAFVEFFCPGQDYQKILKPLFEHYGHDEFAWFATNAAGDFESSSSPSESTETNYSGPV
DVVLDSSATAANSGVNAVTWGVFRGKEIITPTIIEEVSFRAWGDEAFRIWDEWRRIFPRG
SPTEKLLDQLKKDVWLVCVVGQKFGAGAESEEASEAEGRFLWKVLAGKCTNADAAST
>A0A4Q1FIT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. YO12|TrEMBL
MKVTEHIENAKGKTLFSFELIPPQKGKSIQELYDNIDPLMEFQPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNHFAIDLVKQINDLNCGKYLHELMDTDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVYKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A4Q2LG90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillaceae bacterium|TrEMBL
MVKPGLRQALQTEWLAGDGAMGTYLYQKGFPVGISYEEFNTLRPEVIESVHRSYYEAGAR
VIETNTFSANREKLSKYGLENDVELINRAGVRIARSAVGSDAYVVGAVGSIRAGRRLNIQ
NVQLEETFRQQIEILLDEGVDGILLETFYDLEELLIALRTVRNESDTPLICQLAVEDVGR
TLDGFSLKEAFDRLQEAGADVVGLNCRSGPNGIMRAFDTIDGVVQLPFSVFPNAGIPDYV
DGKYMYTATPEYFGDTARQFADRGARLVGGCCGTTPAHIAAIAASLRSYRPQAAAPAVEQ
PEVIVTDSAKDAAPATLNAVPGSSAGAAGTTGALPSIVDQVKQRHTVIVELDPPRDLDIR
KFMAGAAALKAAGVDAVTMADNSLAITRMSNLALASLVQERIGLRPLVHIACRDRNLIGT
QSHMMGLDALDIDHVLAVTGDPARFGDLPGSSSVYDLTSFEMIRMIKQLNEGIAFSGKPL
KQQAKFVVGAAFNPNVKHLDKAVIRLEKKIASGADYIMTQPVYDSGLIERIAEATKHLSV
PVFIGIMPLASGRNAEYLHNEVPGIQLSEDVRSRMAGLEGEAGRAEGVQIAKELLDSALA
HFNGIYLITPFMLYDMTVRLTEHVWSKTKHARSISQ
>A0A2I7SVF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Laceyella sacchari|TrEMBL
MGKPNLIERLRSELLVGDGAMTTYLYQQGVSIGDCTEELVLSDPKLVAGVHQAYYEAGAR
VIETHTYGANRERLTRYGLEGKVTRLNREAVRLARESVGDDAYILGSIGSICAGRMPAYD
EEEYRDMYEEQATALLHAGVDGILLETFLDVKEMLLAVEVIRPLTKLPLLAQFSMLEVGR
TRDAFSISTAFQLLAERGVDGVGLNCRLGPMELLRGLEKTVVPEQLVITAFPNASRLGIT
DGELAYKSNPAYFEQTAELLLEQGVSLLGGCCGTTPEHIRLLAQSLKGRKPVPRRNPQKP
ETAQPVAVEITERVKPTVVEKVRHKRTIVCEFDTPKDLDISAFLHGASRLHQAGVDAITM
ADNSLATARMSNLALGAILKEKMGIEPLVHVACRDRNLLGQQSHLMGLHALGIDQILVIT
GDPTRMGDLPGASSIYDVTSFELIRMVKQLNEGISFAGRQLKQKARFVVGAAFNPHVRQL
DAAVRRLEKKVEAGADFIMTQPVYDAQGIIDVHEATKHIPIPIFIGIMPLTGYRNALFLH
NEVPGIKISPEVLKRMEQQPDKAAGRREGVAVAKELLEVALSRFNGIYLITPFSYWQMSE
ELIRFIHQYDSQHIALRA
>A0A7G5XH82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacibacter sp. S13-6-6|TrEMBL
MKVTEHIAQAKDTLVSFEILPPLKGKTINSIFDHLDPLMEFKPSWINVTYHRAEQVFKKK
PDGTFEKVEVRKRPGTVGICAALQNHYNLDAVPHLICGGFSKRETEDALIDLNFIGVQNV
LVLRGDAAKNETFFEPHPDGHRLAIDLLKQTINLNHGIYLEEDIRDGFRTDFCAGVAGYP
EKHFETPNQEIEMQRLKDKVDAGAEYIMTQMFFDNSKFFAFVKQCREMGIEVPIIPGLKP
LTSKKQLSVIPRTFHVDIPTELSNEMMRAKTDDDCKKVGTDWLIQQSKELKEFGVPVLHY
YTLGSPKVIYNVVKNVL
>A0A8C0I845|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bubo bubo|TrEMBL
CSWELSGAGSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDKWFS
LEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCG
LETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDLVKH
IRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLKFMK
DCQAIGITCPVIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVEL
AVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILT
INSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIV
NVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEE
ESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQHTKAP
>A0A8C0EB77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bubo bubo|TrEMBL
NSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDKWFSLEFFPPRTANAA
VNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQ
TKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDIC
VAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLKFMKDCQAIGITCPVI
PGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSG
MVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKS
YIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFE
VFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNINGKPS
TDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPD
LQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIH
DNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQHETE
>A0A7K9QG26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Irena cyanogastra|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQSKDEITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDVCVAGYPKGHPEAESYEADLRHLKEKVIAGADFIITQLFFRPETFLK
FMKDCQAIGINCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPMKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A5F0LEG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. 3R-11|TrEMBL
MTQHNFSIEFFPPKTPEGTEKLRVTRAKLAELQPKYFSVTFGAGGSTQQGTLDTVLEIIR
EGHVAAPHLSCIGSSRDALRAILTEYKSHGIKKLVALRGDLPSGFGAADFSSGEFRYANE
LVEFIRAETGDWFHIEVGAYPEMHPQAKSPQDDVQNFARKIKAGADAAITQYFYNPDAYF
NFVDEAQKLGVNAPIVPGIMPITNYTQLMRFSDMCGTEIPRWIRLKLASYGDDADSIRAF
GLDVVTQLCEQLLEGGAPGLHFYTLNQPAATMAIWQRLVD
>A0A3E1YB56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga silvatica|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIDSIYDHLDPLMEFKPSFINVTYHRSEHMFKKK
ADGSFEKVEIRKRPGTVGICAAIMNHYNIDAVPHLICGGFSREETENALIDLNFLGIDNV
LVLRGDAPKNETFFEPDPNGHSFAIELLDQVAHMNNGVYLEDDLQGGVKTNFCIGVAGYP
EKHFEAPNMQTDMSHLKKKVEQGADYIVTQMFFDNQKFFDFVARCREMGITVPIIPGLKP
LTTRKQMTMLPRIFHVDIPTDLSTEIMKCKSDKDIEQVGTEWLIAQSKELKAFGVPVLHY
YTLGKPKVIEKAVAAIV
>A0A3N0ARZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adlercreutzia equolifaciens subsp. celatus DSM 18785|TrEMBL
METVARIFESCREDRLSESCVARVAVAQEAGAACTEVSESRARRIPFSVEMFPPKGQLTL
DAARKVVEGLRAASPDFISVTCSAGGSGNGHGGQTVAIAELIQNEAATPAVAHFTCVSAT
ASLVATEVEALRAAGVETVLALRGDLAPGQEPADFRYAYELIPRLKAAGLCVGAAAYPEG
HIDCLDPRENIRHLRAKQDAGADFFITQLFFNNDDFYRFREAAESAGVAAPISCGIMPFL
GKSQIQRMVFLCGSSLPAPIIKLLAKYEDDPVALRQAGIEYACNQLVDLGRHGVNGLHVY
AMNQPDIACAAAEAVAAAGLR
>A0A2X3EU91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae|TrEMBL
MARTLASAIAPTASSKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRG
DLPPGQR
>A0A2Z6NEE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trifolium subterraneum|TrEMBL
MKVIDKIRSAAADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANKMQNIICVETMMHLTCTNMPVDKIDHALETIKSNGIQNVLALRGDPPHGQE
KFVQTEGGFACARDLVQHIRSKYGDYFGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILMS
LGLIEESKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSGN
PSYGALTDYQFMRPRAKDKKLIEEWAVPLKSVEDIYERFRLFCLGKLRTNPWSELDGLQP
ETKIINEHLEKINAKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFSSKEKL
DALIEKTKDRPFTYMAVNKEGIWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFSVWK
DEAFEIWSRAWASLYPEADASRKLVEEVGSSYFLVSLVDNDYINGDLFGVLADF
>A0A5E4RP86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea terrigena|TrEMBL
MSGSHDNRTIMTQPSFSFEFFPPKTAEGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQG
TLDTVVEIQREGVEAAPHLSCVGSTRDNIREILQTYRQHGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGEWFHIEVAAYPEYHPQAKSPRLDLEHFAHKVKAGANAAITQYFF
NADAYFRFVDDASRLGVDVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
DSIRAFGLDVVTALCERLLAQGVPGLHFYTLNAASATKAMWQRLGL
>A0A2G3J9C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Iodobacter sp. BJB302|TrEMBL
MTPSPISFEFFPPRTPEGAEKLRTTRRQLAQFKPEFFSVTFGAGGTTQEGTLNAVLDIQS
EGHSAAPHLSCVGSSKESIRKIVQNYKDHGIRHIVALRGDIPSGMGDFGEFRYANELVSF
LRDEFGDWFHIEVAAYPEFHPQAQSAEADIRNFVNKVRAGADSAITQYFFNADAYFRFVD
EVNARGVTIPIVPGIMPIQNFSQLARFSDMCGAEIPRWLRLRLQAFGDDTASIRAFGLDF
VTELSDRVLAGGAPGLHFYTLNAAGAVSTVCQRLGR
>A0A8J7WYA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovermiculus sp|TrEMBL
MKSKLEAGEFVLLAEMEPPKGVDVSEMVTNVTRIKGLVDGCVVPEMNSAVMRMSSLGGAV
LLQGIGMPAIMQVNCRDRNRLALQADLLAAYACGVRGIMAVTGDDPRFGDHPQAKPVYDI
GLMDLLQAMSRLQQGRDMAGIELQGPPSFKVGSTINPGVKKELLNKEVEDFEAKLEAGVT
YFITPALFELDSIAPFLEAVSPHRFKLIPSVLLLKSLGMARYIARNIEHIHIPDTILKRI
QKAAEKERESVKIAAETATMLKNAGFGGVIITTMGWEQKIPEIIEAMRG
>A0A848B324|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas bovis|TrEMBL
MKRISIELVPRDEAALRESLAVVKQHAAHADVINIPDLLRLPMRSYEGAAVAKEYFKAAM
PHIRAMDIDLSAELPMKDFLRAQEIREVLVIQGDPPQDMTKKVYPTTSTDVIRKFREEMP
EVKVYAGIDQYRGSMSDELYRVKRKLQAGAAGFFTQPFFDLRYLSVYEDMLTGLDVYWGV
APVMSERSQSYWERKNKVVFPQEFAPTLDWSIEFTRRVMAFAQERDESIYIMPIKANLEA
YLAGIFPAV
>A0A183U4M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Toxocara canis|TrEMBL
LSHFFNLRSYRGGSAISGYPTCHPEAPSYAADLRYLKSKVDAGAQLIITQLFFDADVFEK
FVHDCREIGITVPIIPGIMPIQSYESIRRIAAVSQLTIPESILNTLEPIKHDDDAVRSFG
IRHAVEMCRHILSSGSALSVHLYTMNRESSCREILQELGLWTRTPMRSMPWKSFDGNHPL
RAKEDVRPIFWSTRPKAYVFRTRDWDEFPNGRWGNSSSPAFNDLADYYLFYLKGQPTKDE
QLRMYGQELESVEAVKKVFVGFITQQPNEQGVKVTRLPWNEQDLDAETNIIRDQLLWCNE
NGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQK
>A0A8J8BFV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovermiculus sp|TrEMBL
MKTQSRLEKVLRAGHFAFTGELGPPRGTNVQAVKEKASHLKGMVDGVNITDNQTGMVRMS
SWATSLIVQGEGLQPIYQMVCRDRNRLAMQADVLGANALGINTMLCLSGDHQQFGDHPHA
KGVFDIDSIQLLAMVKNMRDPGKFQGGADIDGPPQMFIGAAANPFAEPYAWRVHRLAKKI
QAGADFIQTQCIYNMPRMREWTKQAVDMGLTEKVSILAGVTPMKSVGMAKYMQTKVPGMD
VPEEIVKRLRGVEKKRQKNEGIQIAVEQIQEFKEMEGIAGVHLMAIEWEHRVPEIAELAG
VLPRPEV
>A0A7D4GQF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia dentocariosa|TrEMBL
MTTVHPALSYELYPPRSHASCDSLLKTIAELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLALRGDIPPENTRSLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAARLAGVEMPIIPGIMPVTSLTRLTKLCELAGLEVPRKLAHRLETASEP
REMHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>A0A7Z8G825|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus mirabilis|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTQEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHAIIKDIK
>A0A5B9PSB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariniblastus fucicola|TrEMBL
MIPSTLYQSDKLTLSFELFPPKTEKGEANLYRHVETLMEYQPDFITCTYGAGGSTQTKTL
DIICNVKERFDIPVASHLTLVGSTADQLREYLATAKARGVDHIVALRGDPPEGSNEFEQT
DGGYRYANELVELLHSEFNDFGVFVAGYPEKHREAPNMETDLDNLKRKVDAGADAIITQL
FYCNDDFFRFRDECSSRGINVPVVPGLLPVTDLGQIQRISSLCGAKLPKDFVDALGNTDD
QFQVGIDQAVAQIEALKSGGIEGLHLYVLNKSKATVEIMKRMDGLNCPAQAQ
>A0A255RAW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. P5-126|TrEMBL
MTVTEYIKQNNGERGFSFEVLPPLKGNGTEALFRTIDKLAVFNPGFINITTHHSEYIYRE
LKNGQFERLRVRRRPGTVAIAAAIQQRYNIPVVPHVICSGMTIEDIEYELLDLQFLGIQN
LMLLRGDKAKEDSRFTPTPGGHAHTTDLIEQVVRFNNGTFADGTTIKHPGTKFEFGVASY
PEKHEEAPNLERDMEYLKQKQELGAQYAVTQLFYDNEKYFDFVEKARQMGITIPIIPGIK
PMAKLSQLTVVPKTFHCDIPEALAKEIVKCKTDEQARQLGIEWTTAQCQELYAHGIQNIH
FYTVSAVDSVVEITKRLL
>A0A509JQH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia dentocariosa|TrEMBL
MTTVHPALSYELYPPRSHASCDSLLKTIAELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICVGHSVTDLERSVRLILGLGVRGFLALRGDIPPENTRPLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAARLAGVEMPIIPGIMPVTSLTRLTKLCELAGLEVPRELAHRLETASDP
RELHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>A0A2G9DI38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. JV178|TrEMBL
MTAPGLSALLRRVRYEVLPARATEEKVLAHVPRDVVVTVTASPVKGLEPTLDLTARLAAH
GYRVVPHVPARLLRDDAHLKETVDRLRESGVDDVFVPAGDADPPAGTYDGALPVLRRLSE
LGRPFAEVGVTGYPESHPLIHDDITVQAMWDKREHATYVVSNLCFDPRVLGQWIARVRTR
GVELPVYVGVAGPVQRAKLLATATKIGVGESTRFLARHPLWFLRFAAPGGYSPEALLTRS
EGALTAPSAGVAGLHLFTFNQIAETEAWRRNLLDRLGG
>A0A1F8QC21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_56_11|TrEMBL
MVSRFKEALNSGKFVITSEVAPPKGTNLDKMRHHIDILKDKVDAINVTDHQSSVMRFPSL
GGCLAIKEKGGEAILQMTCRDRNRMALEADLLFAHSRGIGNVLCLTGDAVPVGDHKEAKG
VFDLDSLQLLKTIRQMAAGQDLGGNKLEGVIEFCAGAIVTPEARPIEPQLIKFEKKVEAG
AEFFQTQAIYDLENFARFMEYARKLKTKILAGIVLLSSARMAKYMTENVPGIFVPQNLID
ELAATPKDKVLAKGIEIAGRTIATLKKAAICQGVHIMAIGKEEVVPDILAAAGL
>A0A435N9D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.15.1.1|TrEMBL
DVPMFRTYMQKVRDLGYTEKCFILVGVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQ
DQKKEGKQLCIDIINEVKEISGVSGVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRD
DQMVADRLEHILHDDITETQVDMVKTAH
>A0A1F3BL48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium RBG_16_58_9|TrEMBL
MGLAEVLKNGHPVVMVECTPPRGSDATSLKSCAEALGKSVDAICAPESEDGPRLSSLAAC
SHLVAAGAEPVLHLLTRDLNRIALQSALLGAASMGIRNVLCLSGRHQALTTSASARGVYD
IDHDQLLRLADSIRKDGVLADGQSMDSPVDLVLGTDTNPFSDPIELQVIALEKAVRSGAD
FVITHGVFNLDRFNVWMTHVRERGLHEKTAVIAGVMPITSARQAVSLAEKYSHLDIGDDV
VERLDSAQDKRAAGVHLAAETIAYVRKVPGVRGVYISTGEDYQLAADVIAAAGLARK
>A0A8A4K898|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea ananas|TrEMBL
MSFFHANQREALNQSLAELNGRISVSFEFFPPRTSEMEETLWNSIHRLSSLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELQAIAQDYWNNGIRHIVALRGD
LPPNSGKPEMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFAALTNVRVPGWMNAMFA
GLDGDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGIAA
>A0A7H8Z8W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. oral taxon 061|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQDLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFINEQAPHFEIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQP
>A0A199YHI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira profundimaris|TrEMBL
MMTVPEINAVRKHLKVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGTTRDR
THGSVTRIQGETGIPAAAHLTCVGHTKEEIDQIARSYWNEGIRSIVALRGDLPDAGDKYE
PTPGGYAYAVDLVAGLKEIADFDISVSAYPETHPDAPSSDFEIDYLKRKIDAGAKRAITQ
FFFDNETYLRFRDKCVAAGIEAPIVPGILPVTNFASLLKFADMCGASVPQRLHWRFEGLD
EDPDTRRMVAFHEAISQVEGLISEGVTDFHFYTLNRAELTYAICHALGIRGTEQVAA
>A0A351GQG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MSRPQISFEFFPPQNFEGAYRLWDTVNTLAPLNPRFMSVTYGAGGTTRTLTQEATRVLHK
HTGCDVAAHLTCVDATRDETLNVARSYTDTGVTGLVALRGDPPAESGTFRAHEDGFENTV
ELVGALADLDAFRLFVGAYPQTHPEAADAAQNIDWLKQKLDAGADEALTQFFFEAEDFLR
FRDACAKAGITKPITPGILPIENWQGVKRFAKRCGATLPVWLEDAYAKAERDQRTDLLSI
ALCTELCSELVDEGVEALHFYTLNRPELTRDVCAALGIHPKVTLQHVA
>A0A3S3TZK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. 24NR|TrEMBL
MMDTTSTASAPFHLSFEFFPPKSDEMEVQLWEAVEQLSPWQADFVSMTYGAGGSTKEPTL
AAVRRMIGDAGLDTAAHLTCVDASKDEVRAVVEEYRAAGVRRIVALRGDPTTGLGTSYTP
HPQGFSDTSDLVRMLVEYGDLDVSVSAYPEKHPESPDLAADIDTLKRKADAGAARALSQF
FFDNDVFETYLEKVQAAGVSIPVVAGIMPIQNLSQLKRFARRCGSSVPAFLDQRFEGLDE
KPQERAEVAADIAAEQIADLMRRGVSEFHIYTMNRAPLVSAVLQRLGRAQGQGAKIGAAA
>D7XZZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli (strain MS 115-1)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A235IZR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. 'Peltigera membranacea cyanobiont' 232|TrEMBL
MHYTHSSTAFQRAVQAGEFLVTAEVAPPKGGDPTHMIQMAATLKGRVHAVNVTDGSRAVL
RMSSLMASVILSQNGIEPICQIACRDRNRISLQADLMGAHALGIRNILALTGDPVKAGDH
PDAKAVFDLEAVRLLQLIRKMNQGVDCNEKPLTDGALDLFVGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFDVLEKFMDTIAAGYKKPILAGIFLLKSAKNAQFINRCVPGVN
IPQHIIDRLAKAKDPFEEGIKIAAEQVQIARQLCQGVHMMAVKREDAIAPILDLAGIAPV
NQLVST
>A0A357MGS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTPPAVSFEFFPPKNLEASFRLWDSVQALAPLDPRFVSVTYGAGGTTRDLTRDAVATIHK
HSGLKVAAHLTCVNASKSETLAIAEGFAQAGVTDIVALRGDPPKGEGRFTPHPDGFRDSL
ELIEALAETGRFTIRVGAYPDPHPESAAGMSDVEWLKRKFDAGAHEALTQFFFEAETFFR
FRDACDKAGIDKPITPGVLPIENWTGARKFALSCGTVIPQWVDDAFETAARDGRSDLLAT
ALCTELCSDLIEGGVERLHFYTLNRPELTRDVCHALGVTPRAKLENVA
>A0A5C2T1X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentinus tigrinus ALCF2SS1-6|TrEMBL
MKFVDKIAQHDARSLFYTFEFFPPKTDQGFENLVARIARMVTLNPLAVSVTWGAGGTTKE
RSLDLAGLTQLEYGMDTILHLTCTNMVQGTVDAALREAKERGIENILALRGDPPRGAEHW
IPTDSRFQHGADLVRYIKSTPEFADFCVGVAAYPDGHPDRETNEDGEIEHLKEKVDAGAD
FIITQLFYDVDGFLQWHQKVRAKGITVPIIPGIMPIQTYASFLRMTKLCATRVPPKMMHD
LVPIRHDDQKVKEYGVKLAVDMIKQLQAGGIQGVHFCTLNLEKSVTRVLETLGLAGNISQ
ATNKLIADVATPPERTMTPHAASDRATKELASVPAPESDAGKGEINNAADWDDFPNGRFG
DFKSPAYGETDRWGSSAFQSKALAVPLSQWGNPKTADDLTSLFLRYLHSKVTATPFSSTP
LSPESLMIFPHLERLTSKGWWTVGSQPPVNGAPSTHDIVGWGPRGGYVYQKCFVEFFVEQ
KDVERIVKKVEEEGAGWISYFAGNAKGELLTNVPEGGRNAVTWGVFPGQEIAQTTIIEKE
SFLSWKDEAFSIWSEWASFYPPASQERSLLEGIYNGRWLVSLVHHDYLDPATLWTFLFKG
DHPLL
>A0A317Y291|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zea mays|TrEMBL
MKVIEKILEAAGDGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLK
RKNTFLLVHEPNNKLKTVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPIN
NYKGFLRMTGFCKTKIPSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILATGIKTLHLY
TLNMDKSAIGILMNLGLIEESKVSRPLPWRPATNVFRVKEDVRPIFWANRPKSYLKRTLG
WDQYPHGRWGDSRNPSYGALTDHQFTRPRGRGKKLQEEWAVPLKSVEDISERFTNFCQGK
LTSSPWSELDGLQPETKIIDDQLVNINQKGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKI
KAFPSLTYIAVNKDGETFSNISPNAVNAVTWGVFPGKEIIQPTVVDHASFMVWKDEAFEI
WTRGWGCMFPEGDSSRELLEKVQKTYYLVSLVDNDYVQGDLFAAFKI
>A0A4U7KSQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporisorium graminicola|TrEMBL
MISTSTVPPSAGASITASDPAHITSKIRAASTRDAPFWSFEFFPPKTTQGLANLYNRIAR
MRANLDPSWIHVTWGAGGTTGGKSLELAGRIQKGKLDPDVEIVQKEVKQIGSGAQQHIEN
VKGGESWEKEGPDACDVCLHLTCTNVEKSSLDETLETAKRLGIKNILALRGDPPRGEEYW
VAADERFQHATDLVRYIRQNHGDFFCIGVAGYPEGHADYVDRDVKRDLRYLKEKQDAGAQ
YIVTQLFYDVDQFLSWYKDCRAIGITIPILPGIMPIQNYSSFRRMTNLCKVQVPQLILDA
LEPIKSDDAAVKEYGVSLSIHIVGRIFLESDIRGFHLCSLNLEKSIERILEGLGWKTDLG
AQLETDPRLRGIPAHLHLEATKNQMLSDRTGANTPKDFKVTTQEALARTLARTSSSYQVP
ETSTWDEFPNGRYGDSRSPAFGEMDGYGVSLKVPPQDALRIWGHPVTLVDISKIFASYLE
EKISCIPWCDAPLMNETLQIRDHLLSLNRLAEGETQSGKGWWSVGSQPAVDGAPSTDPTV
GFGPPGGFIFQKSFVELFMSTADKDKLVARIDALGANAQITYFAGNARGDFQSNLGDGEA
NTVTWAVFPGKEIVQSTIIERDSFEAWREEAFEIWGEWSLLFPKQSASRKLIEEIKDGRW
LVTVVHHDYKKSEALWHFLAE
>A0A2A4ZFN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTTPEISFEFFPPQNLEASFRLWDTVQVLSPLDPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNASRAETLDIADQFATAGVRDIVALRGDPPKGAGGFTPHPEGFATSV
DLIEALAETGKFNIRVGAYPDRHPEATSPDADVDWLKRKIDAGASEALTQFFFEAETFFR
FRDKCAKAGIDHVLTPGILPIENWKGARNFAKRCGTVIPTWLDDAFDKAVRDDREDLLAT
AICSELCSDLLDGGVDKLHFYTMNRPELTRDVCHALGVSPKVALENVA
>A0A6P1BED8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium uaiense|TrEMBL
MTEIISSVPNGQRTPKAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTISRILRETDLLPAAHLTCVSASRSEIDDIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAGIKKRHADIEISVSAYPEKHPEATDFDADIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A840UQ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoprunum benzoelyticum|TrEMBL
MDLKTNSRLEKVLKSGQLAVTSECGPPRSSAPEGIIKKGNLIKNHVDAINITDNQTSVTR
LCSLAACVHLKLQGLDPVLQMVVRDRNRIALQSDILGAASFGINNVLCLSGDHQSFGDNP
QAQNVFDLDSMQLVQTVRRMRDEGRFLSGDEIKVPPNMFVGAAANPFADPFKIRVPRLAK
KIAAGAEFIQTQCIYNVEKFELWMQGVRDRGLHDKVFILAGITPMRSVGMAKYLRKSVPG
MDVPEELIKRLSGVEKEKQAAEGITIAVETIQRLKEVKGVAGFHVMAIEWEEKVPEIVER
AGLFPRPVID
>A0A060LXY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus lehensis G1|TrEMBL
MSRLDLKKLLTSSVTVADGAIGTLLYEAGYDLCFEELNVTKPEEIYAIHQAYIEAGATII
QTNSYAANAQKLKRYGLQESVGAINQASVQLARKAVQDSGKKQVFVLGTVGGIQGFQSEQ
LDYKESMQALVEQVDLLLQAEVDGLLFETFYDFSEIKQLVIEARKRTQLPIIANVSLGDI
GVLKGGIRLSDALTELYEVGADVTGLNCRMGPYHMLRSIEELELPYDIPLACYPNASLPG
YRDGRFVYASNTDYFTSMSERFINEGVHLIGGCCGTTPAHIKAIKEAASGRKPVKRKIRL
QSLKTETIERFHEQRPSIKDLVEEKQTIIVELDPPKKLHIDPFIEGAKAIRDAGADALTL
ADNSLASPRIDNQTLAMLLKEEGIRSLVHLTCRDRNLIGLQSHLMGLDLAELNDLLVITG
DPSKIGDFPGATSVYDVSSTKLLPLIKQMNEGISFSGKSLGRATNFTTAAAFNPNVKHLD
KAVRRLEKKIEAGAHYFLTQPIFDERQFEEVYEATKHLSVPIFVGIMPLTSSRNAEFLHN
EVPGISLSDDTRVRMARAGEDKMKAEQEGLAMAKSLADAAATYFNGLYLITPFLRYRLTV
ELTRYLRTHTTAPLSKERKLQ
>A0A6P1WIM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae 248|TrEMBL
MALKNEARGRNDIRVSFEFFPPKSEEMEGQLWHAVSQLQDWDPDFVSVTYGAGGTTKAPT
LSTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYR
PHSGGYANAAELVVGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQ
FFFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFD
DKPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRRQTKSAGAA
A
>A0A8D5REF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus hoagii|TrEMBL
MSTNQSSASLAGLDPEVATATAGELSRQRDTLESRTPSIVDRIGAPDAGRIPFSVEFSPP
RDEAAEARLWRAVRAFERMDPAFVSMTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAV
GHSVDELRAMCGAYADRGVSNVLVLRGDPPGDPLGEWVKHPDGVEYAEELVRLVRDMGDF
HVGVASFPEGHYRAPDLEHDTKYLVQKLRAGAEYSITQMFFDVEDYLRLRDRVVAHDSEQ
GEKPIIPELMPITSLRSARRSLELSGSSLPPALEERLTRAAGDGPEENQAAVREIGIEVA
TQMAERLIAEGAPCLHFITLNFARATSEVLANLGYASRVA
>R6Q152|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:55|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPE
AMKQAGIAYATDQIIDLLANGVNNIHIYSMNKPEIAIAIMNNLSEIIKC
>G0A4U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas methanica (strain MC09)|TrEMBL
MNISFEIVPRSLEAFEQQYAFVQALDKGISFINIPDIQRFDTRSWELASRIDRSKYRFVP
HFRAIDFKIESGELYRIIEQYELDSVLLVTGDPPEGLKRAYYNTDVVDLIRAVRQRFPQL
NIYAGFDPHRQGLQDECDYTQRKADAGATGFFSQPFYDHRLIEIYAEHMEGLETYIGISP
ITTMASMHYWEVKNKVKFPKSFRPDYDWNVDFANNVIASAAANGWNVYFMPIRIDLNKYF
ERINFG
>F9Y3H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ketogulonicigenium vulgare (strain WSH-001)|TrEMBL
MSAPIISFEFFPPRNLEAAFRLWDTVKALAPLRPAFVSVTYGAGGTTRQLTQEAVVAIHK
ATGLNVAAHLTCVNATRDETLAIADDYAAAGVTQIVALRGDPPKGAGKFTPQPDGFQNSV
ELIAALAATGKFKLRVGAYPERHPDAANTAQDVEWLKRKFDAGADSALTQFFFDTEAYFR
FLDLCEKAGITGKIIPGILPVENWTGARRFAESCGAHIPPAVIAAFEAAPNDATAVAIDL
ATQMSQQLMQAGADHLHYYTLNKPDLSLAIAANLGIRP
>A0A0R3DMI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium pachyrhizi|TrEMBL
MTETISSVPNAPRAPKAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTITRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVTGIKRRHADIEISVSAYPEKHPEAKDFDADIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A1I1R400|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klenkia taihuensis|TrEMBL
MAVVDGPRAGGARVARPGRAELVAALRDATYEVLPFRSAEEKVLADVPTDVALTVTTTEA
KGLGPTVDLAVRLTGAGYRAAPHLAARLVRDRAHLADLVAQLTEAGVDRVFVIGGDAAEP
AGTYVDALGLLESLDDLGRPFATVGIGGYPEGHGSIAAEHIERALEAKAAHATQVITQLC
FDAGTTVDWARTVQQRGVTLPIRVGIPGAISRQKLIRVSAGLGLGQSARFLKKQQNMFWR
FFLPGGYSPDRLIQRLTPAFGRTDNGLHGLHVFTFNELDTTEAWRQRWLARLG
>G0A4S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas methanica (strain MC09)|TrEMBL
MEAFDTQYAFVQKLDDGINIINVPDIQRFETRSWELATRIDRSKFRFIPHFRAIDFKIDG
GELFRIIEDYRLDSVLLVSGDPPEGLKRAYYNTDVVDLIRVVRRRFPTLNIYAGFDPHRQ
GLQDECDYTQRKADAGATGFFSQPFYDHRLIEIYAEHMRGLETFIGISPITTQASMNYWE
VKNKVKFPKGFRPDYDWNVEFANSVIVAAATAGLNVYFMPIRIDLERYFQRINLI
>A0A2U3JVL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacter sp. SbD1|TrEMBL
MSTTTPSKLEKILAAGHFAVTSECGPPRSCDQSIVDEKARLVGPYVDVINVTDNQTAVVR
MCSLASCIRIKQLGFEPVLQMTTRDRNRIGLQSDLLGAGAFGINNVLCLTGDHQRFGDHP
TAANVFDLDSTQLIQTVKRMRDEGKLLGGQEMAEGVRPQLFIGAAENPFADPFEIRVLRL
AKKVAAGAQFIQTQCIYNMEKFKLWMQQIVDRGLNEKVSILAGITPMKSVGMAKYMKAKV
PGMDVPDEIIKRLQGVPKDKVAAEGVTMAVEQIQELKECPGVRGFHIMAIEWEVMVPEIV
ERAGLSPRPEVS
>A0A2P9FCJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MA5143a|TrEMBL
MTAPGLSALLRRVRYEVLPARATEEKVLAHVPRDVVVTVTASPVKGLEPTLDLAARLAAH
GYRVVPHVPARLLRDDAHLKETVDRLRESGVDDVFVPAGDADPPAGTYDGALPVLRRLSE
LGRPFAEVGVTGYPESHPLIHDDITVQAMWDKREHATYVVSNLCFDPRVLGQWIARVRGR
GVELPVYVGVAGPVQRAKLLAMATKIGVGESTRFLARHPLWFLRFAAPGGYSPEALLTRS
EGALTAPSAGVAGLHLFTFNQIAETEAWRRTLLDRLDG
>A0A846NWY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aenigmarchaeota archaeon|TrEMBL
MAKDKIFSNLMKEIVDGKFVLTGELEPVKEGNIEPTIDAARRLKGHVVACNVTDNPQSFG
YVNSIMSAFIVQTKTRMECIAQMRCSDRNRLALLSDVLGAGLLGVRNVLAITGDYVSLGD
NSGAKPVYDLDSTTLTHMISRVVKEGKDLNGNDVKDPPELHIAVAANPGAEILEVELYKL
KR
>A0A8B7MPY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila elegans|TrEMBL
MHAIQESAGGPSYTSYIPCVTFAPGQNASTMEEQRIGPLVAQRTAQRRIFYGIEVTASEP
GGKPTCLDFNQFLPLLPTFVSVVWLGQRYWDVEPVGQVESLQLAKHLATHIPVLPHLSAY
RLQRKRLDQFLALNFSSLLAVRGDQVHEGQEFRIAQPMVEQSRRQRGERISICVPGYPEG
YTSLGDVPPDSARNIKFLKAKVAAGADCIITQICYRPEAIVQFVRDCRAAGITVPIVVGL
MTHETFRTYSTIERIVGVHLPNELREELNQLRSHHNSTTKSEPNRISRYFVSLTVRIIRH
ILDANRCFKNFGNWIYFRFLIWREN
>A0A7C2EW44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division NC10 bacterium|TrEMBL
MRFGEAYGKGKFGLSFEIFPPKTPAGDEALFATVEALMQFRPSFVTCTYGAGGSTREKTL
ELTVAIRERFGVSTAAHLTCVGSSYDDLRAWLRRASAQGIENIVALRGDPPRGATRFVPA
DAGPAHADELVALIRREFPQLSIAVAGYPETHQEAPSPEVDLANLKRKVEAGADVVITQL
FYDNRDFFGFQRRYREAGIRVPLVPGILPIINFTQIRRITSLCGAMLPPSLVAQLEAKQD
DPEAELEIGVAHAIRQCRELLDAGVPGLHLYVLNKATAPARILEALELHVLRGASA
>A0A7Y4EPZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 99-70-13A1|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASRDELIQIADDYWANGIQSIVALRGD
IPEGGGAPDMYASDLVNLLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAQQFQ
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAI
>A0A8B6ZYP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orycteropus afer afer|TrEMBL
MVNEARGSSGPSPHLEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRIESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCRQSREEITGHLHRAKRLGLKNILALRGDPIGEQWEEEEGGFSYATDLVKH
IRSEFGDYFDICVAGYPKGHPEAESFEADVKYLKEKVSAGADFIITQLFFEADTFFQFVK
ACTEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIEL
AVRLCKELLASGLVPGLHFYTLNREVAIIEVLKRLGMWTEDPRRPLPWAISAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFEVFAHYLSGEPNQNGCKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSREMVEALLQVLKRYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYVHDNYFLVNLVDNDFPLENCLWQVMEDTFELLNRPTPE
>A0A2T5GVH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. PP-CE-3G-477|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGISFEFFPPKSEKMETQLWEAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISIAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPVDKVAAA
>M1X170|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Richelia intracellularis HH01|TrEMBL
MNAFRQAIEAGSFLVTAEVTPPKGGDPSHMIQMAATLKGRVHAVNITDGSRAVLRMSSLS
ASAILLQHGIEPICQMACRDRNRIGLQADLMGAYALGIRNVLALTGDPVKVGDNPEAKGV
FDLEAIRLLQTIDKLNHGFDYNEKPLINGGLDLLVGAAVDPQSRSWSGLQKRFERKVKAG
ARFFQSQLVTDFDLLDKFMNTIAAGCNIPIIAGVFLLKSAKNANFINRMVPGVNIPERII
ERLEGAKDPLEEGVKIAAEQVKAARDICRGVHIMAVKREDLVSPILDIAGIKPVIELGLE
TKVPK
>A0A429DA12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. WAC 04169|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDTADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTPRTLHTSIKLSGAPAPRRLLDRLEPLA
GDPKAFRAEGIDAVTELCERLIAEGVPDLHFYTFNRSKATREVVGRLGLVPARA
>A0A1M5NIE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium erythrophlei|TrEMBL
MSAPDHASSRQLDALLSSASVEISSRGHQLGELRDRFAAGTDVTITFLPGDNYRHNVETA
AMLRRAGFNAVPHVAAREMPSREALDDFLTRLRGEADVRRILLIAGDVAAAKGPFKSSHD
VRASGLIEEHGMARVSVAGYPEGHPYLGLAATFSGLEAWRDWGQGTKIHVDVVTQFCFES
APILAFIGELDARGVGLPVTVGLAGPASPATLTKFALRCGIGNSIRSLRSQIGRFGRLLM
DTGPDDIMRGLQLAPEVVTASISGFHLFPFGGLRKAAEWSRGYVAETLRQAGRTASRTGA
QNL
>A0A3M5WRC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. apii|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A5S9NV14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Starkeya sp. HF14-78462|TrEMBL
MSSDVERRSRRAGGRPISVSFEFFPPKTPEMEATLWNSITRLAPLAPKFVSVTYGAGGST
RERTHTTVERIVKETRLAPAAHLTCVSATKAEVDEVVRGYWDAGVRHIVALRGDPPGGVG
QAYEPHPEGYRTTADLVDGIRRIANFEVSVSAYPEKHPESPSFDTDLDILAAKVEAGATR
AITQCFFDNDLYFAYLDKVRARGIDVPVVPGILPVSNFKQARNFAEKTGTYVPSWLTSRF
EGLDNDPETRKLIAAAVAAEQVFDLVDRGVTEFHFYTLNRADLVYAVCHLLGIRPPQESA
GQSNGQAAA
>A0A2T3NCX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium rosenbergii|TrEMBL
MGYSYASHLDSLNQNIADIDGNINVSFEFFPPSSEQMEQTLWNSIHRLKTLQPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLVAAPHLTCIDATRDELRSIARDYWNNGIRDIVALRGD
LPEQGAKPDMYAADLVELLRSEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNMKQAKRFANANNVKIPGWLEKQYE
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAKA
>A0A1G0D5M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium RIFCSPLOWO2_02_60_31|TrEMBL
MNKPLFSFEFFPPHTPEGVEKLAATRKQLAALHPEFFSVTFGAGGSTQERSLEIVQQIKA
EGLEVAPHLSCIGSTRENIRSILQTYRQLGIRRIVALRGDLPSGMATTGEFQYANELVSF
IRAQTGEHFHIEVAAYPEVHPQARSAQDDLVNFKRKAAAGADSAITQYFYNADSYFHFVD
ECRKIGVTLPIVPGIMPIVKFAQLARFSDTCGAEIPRWIRRTLEGYGDDNESVQAFGLDV
VTQLCEKLLAGGAPGLHFYTLNQAGPSLEIWKRLG
>A0A0P8D6C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phormidium sp. OSCR|TrEMBL
MSRLRTAIHTGEFLITAEVAPPKGGDPSHMLKMATCLKRRVHAVNITDGSRAVLRMSSLA
ASALLVQYGIEPVFQVACRDRNRIALQADLMGAYALGIRNVLALTGDPVKAGDHEKAKSV
FDLESVRLLQTLQKMNQGLDFNDKPLSDGKLDLFGGAAVDPQLASWSGLQRRFERKIAAG
AQFFQSQLISDFDRLDKFMTQIAARYDKPILAGIFLLKSAKNAKFINKYVPGVHITDETI
DRLDEAADPLREGMAIAAEQIKQARCLCQGVHLMAIRTEHLIPEILDMAGIPPISRPSSL
QR
>A0A3R6Q3M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. AF14-59|TrEMBL
MKVIDLINGSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFNPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQNTDLYHEHATGLQQQVNNFNKGIAIDGSTFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVDRCRAEGITVPIIPGIKPV
VFKTQLTVLPKIFRSDIPEPFAAELRKCKNDDEVKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMATDSVYKVAKEVY
>A0A2E5C9Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peredibacter sp|TrEMBL
MTKVVDHLKNSDETLFSFEILPPIKGHGIKKLFSQVEPLMEFQPKFIDVTYHREEYIYKK
RQNGLLEKVSLRKRPGTVGICAALMNKFQVDPVPHLICGGFTKEETESALMDCHFLGIDN
VLALRGDAIKSENRFVPTEGGNAYASELVKQIADMNKGQYLYQEDAGAEATSFCTGVAGY
PEKHFEAPNFNTDLKHLKRKVDLGAEYIVTQMFFDNSKFFKFVDECRAAGINVPIIPGLK
PLTTMRQLSILPSIFFIDLPDDLVHAVENCKTNEDVRKVGIEWSINQCKELKKHNVPCLH
FYSMGKSDNIKTIASEIF
>A0A7S9WHA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium|TrEMBL
MSTPRISFEFFPPQSIEASFRLWDTLGKLAPLSPEFVSVTYGAGGTTRDLTHDAVKTIHA
NYGVAVAAHLTCVNATREETLAIADSYAEAGVTEIVALRGDPPKGAGKFTPHPEGFASSV
ELVEALAKTGKFHLRVGAYPDPHPEAENLDACVEFLKRKVDAGANSAITQFFFEADTFFR
FRDACADAGINAPIIPGILPVNNWTRVRRFASACGAHIPAWVDEAYEKAIRDDRETLLST
ALCTELCSDLIEGGVDDLHFYTLNTPELTRDICAALGVTPKQALAQVA
>A0A6G1Q1Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Channa argus|TrEMBL
MVNQVQRGGGCWQSCKSDSSGASNSGGESSKESSRCSTPVLDADRSDRLRDKMRRRMESR
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPSGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKENITGHLAKAKHLGLKNIMALRGDPIGADWEEEEGGFNYAV
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTF
LKFVDDCKANGITCPILPGIFPIQGYQSLRQLVKLSKLEVPDEITKVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWKEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LVQMWGEELMNEESVYEVFTCYITGQQNCNGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVDALLKVLKKYEPRV
NYHIVNVHGRNLTNALDLQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWQVINDMFELLDAPPEPQSRLNN
>A0A7U9H3P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium butyricum 60E.3|TrEMBL
MIKEFLNNNILICDGAMGTYYSEKTGNDISYCEFGNLNDKNTIRRIHEEYIEAGAKLIRT
NTFSANSKELGVSRKTLKDIIESGIEIAKEAVYNKEVFIGASIGPIRENGADENFVEVLE
EYKFIVDCFLDNNINVFIFETLSNLDYLEEVSTYIKNKKPESFILTQFAVKPDGFTRDGY
SVSKIVGEVKKINTIDSYGFNCGSGPTHALELIKKIDIGDDIVSSLPNAGFPEIIHERTV
YPNNPVYFARKVKEIKKLGVSIIGGCCGTNPSYISKLRDTIDNKPEAGDKIKRYEHETYN
EKNIIKNTFKEKVKNGDFVIAVELSAPVDTDINKIMTGAKVCKDNNIDIVTVPDSPMSKV
RADSVVMSSKIKREIGIEAMPHMCCRDKNTNAIRSSLIGGHIEEIRNILAITGDPISDAS
RIETKSVFNLNSFKLIELINDMNNEVFTSDDIFIGGALNLNVLNKEVEYGRMMKKVERGA
KFFLTQPIYDDSAVEFLKSIKERIDVKILGGILPVVSYRNAMFLNNELPGVTIPQEILNR
FSEDMSREEGQNIGIDIAVSMGKKLKGICDGLYFITPFGRVNMIVDIVNRIKEV
>A0A3C2D8Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prolixibacteraceae bacterium|TrEMBL
MKVIDIINQSNKTVFSFELLPPLKGNDASKIYKTIENLLYFDPKYINITTHRDEMMYMEL
PDGHIEKRTVRKRPGTVAIASSIQHKYGIPVVPHILCGGFSKSETEHVLIDLDFMGIQNV
LALRGDGNKGEQVFRPDPNGHANANELVEQIVNLRKGKYLEPELKNTHSMDFCIGVAGYP
EKHFEAPNAEIDLYYLKRKVEAGAEYIVTQMFFDNRKYYDFVDRCRAIGIQVPIIPGIKP
INLKNQLTVLPKLFSIDIPLELVTELATCQTDDDAKAVGTEWAIQQSKDLVAHKVPSLHI
YTYGVSDNTRRLVEAVF
>A0A1F4KGQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFCSPLOWO2_12_FULL_61_40|TrEMBL
MKFEDEPVPGYPLPILPGHTSPGRLERVLRSGAFAVTSELDPPDSADPQDVYSRARVFDG
YVDAINATDGSGANCHMSSLAVCALLTRIGYAPVMQISCRDKNRIAIQGDILGGAAMGVA
NMLCLTGDGVQSGDHPQAKPVFDLDCMSLLGIGRTLRDDHQFQSGRKVTYAPRVFLGAAA
NPFGLPYEWRAQRLAKKVEAGAQFIQTQYCYDVPRLKVFLREIEDLGLLGKVFILVGVGP
LRSAKAADWMRTHVPGIHIPDTVIQRMAGAQKPALEGRQVCIDLIQEIQDLKGVSGVHVM
AFRQEETVAEIIQKSGVLKGRVPWYPGRDSDIQLRKEAA
>K1JCF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas veronii AMC34|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPEMYATDLVALLKAEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLENDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQP
>A0A1V2W805|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cenocepacia|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>V2URE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter brisouii CIP 110357|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRAVHQDLQQLNPEFFSITYGAGGSTRERTLAAISDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDLDIQRFAEKVHAGANSAITQFFFNPDAYFYFI
ERIAKLGVHIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSKSIQAFGHE
VVVKLCERLIAGGAPSLHFYTMNHIQPNRQLVTDLGLA
>A0A350YUL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prolixibacteraceae bacterium|TrEMBL
MKVTDIIRESGKTIFSFELLPPLKGNDASRINRTIESLLDFNPGYINITTHRDEIEYKEQ
PDGTITRKTVRKRPGTVAIAAAIQHKYNIPVVPHILCGGFTKSETEHVLIDLNFMGIRNV
LALRGDGRKGDSVFRPEPEGHAHANELVEQIVNLKNGKYLDPDLKNNHPMDFCIGVAGYP
EKHLEAPNRETDLLYLKQKVDAGADYIVTQMFFDNAVYFSFVEKCRQMGITVPIIPG
>A0A257E395|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. PGPPP1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTQYQQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEEDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCESLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0Q7ECB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. Root1279|TrEMBL
MTAPALSLAEARALLLSPLGPVARAGKDSSRPRVSFEFFPPKSDEAEANLWKAVTRLAPL
QPDFVSVTYGAGGSTRERTHRTVQRILGETELTPAAHLTCVEASREEVDDVIDGYRAAGV
RHIVALRGDPPGGHAGGIGGAYAPRADGYANATELTAAVARRGGFEISVGCYPEGHPESP
SLAHDIDVLKAKVDAGATRAISQFFFDIDAFLRFRDRVRAAGINVPLVPGVMPVTNFAGL
QRMSAGCGASVPDWLAAHFDGLDGDPETRKLIAASVAAETCARLQEEGFADFHFYTLNRA
DLVYAICRVLGVREQRADA
>A0A2N1ZHB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium HGW-Gammaproteobacteria-12|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLPR
>A0A6A4RC26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagicola marinus|TrEMBL
MTTPEISFEFFPPQNLEASFRLWDTVQVLSPLDPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNASRAETLAIADQFASAGVNDIVALRGDPPKGAGGFTQHEDGFANSV
ELIEALADTGKFNIRVGAYPDRHPEATGPDSDVDWLKRKIDAGASEALTQFFFEADTFFR
FRDKCAKAGIDHVLTPGILPIENWKGARNFARRCGTVIPQWLDDAFETAMRDSREDLLAT
AICTELCSELLDGGVDKLHFYTMNRPELTRDVCHALGVAPKVSLENVA
>U4QI94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium pusense|TrEMBL
MQAEVAGARKRKDIVMGIPNAVNSANQSDVLRGFSVEVTTKDTSQLAGLSDAIPKGTIVS
VPFLSTESDADRITAARMTRWAGYEPMPHIAARRLSSEAALSSMLSDLVNEAQVSRLLIL
AGDADPPKGPFKDTATILRSGILEHYGIRHVSIAGHPEGHPIQSGAMLNAALLEKRQILK
EAGIEWSIFTQFAFTSEKVLAWTAELRRSGITAPIHIGIPGPASVKTLLKFAAVCGVSAS
TAVLKKYGLSITQLLSSAGPDVLVGEYAAALGHSAYGDVRLHFYPFGGIRKTINWLEDYR
SRD
>A0A2G6I6F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium|TrEMBL
MPTPRISFEFFPPQDIAGAFRLSDTLRDLAPLGPDFVSVTYGAGGTTRALTHDAVATIGR
RYGLRVAAHLTCVGATKAETLAIADRYAEAGVTDIVALRGDPPKGEGAFRPHPDGFADTV
ALVEALAATGRFNIRVGAYPEPHPEAVGPGADVAWLKRKIDAGASSAITQFFFEAETFFR
FRDACEKAGISAPIIPGILPVENWAGVKRFAARCGARVPVWMDAAFAKAARDRRQRLLAV
ALAAELASDLVDGGVEALHFYTMNKPGLTRDVARALGVVPDAGLRNVA
>A0A1I5WAG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio proteoclasticus|TrEMBL
MKITEIFKEKEVTLSFEVFPPKTDNGYPAVEKAAAEIAALGPDFMSVTYGAGGGTSKNTA
SIAADLQDKYHVPVLAHLTCVSSDKDHVRKMINTYKEKGIENIMALRGDIPKEGRTHFDY
NHATELIYDIKSVDPDICIGGACYPEGHIECTRQSEDIQHLKEKVEAGCDFLTTQMFFDN
STLYQFLYRIKDKGIDVPVIPGIMPITNEKQVARSVALSGSTIPQKMKIMVDRFQDNPEK
LKEAGIIYACDQIIDLISNGVSHIHVYSMNKPDIAAGIMRNLGAIIK
>A0A1E4SG34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Suhomyces tanzawaensis NRRL Y-17324|TrEMBL
MRISQKLAQAHSSPNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSSLTNDMVYTAQSTLGLETCMHLTCTNMKVELIDEALQKAYASGCENILALRGDPPLD
GSESTGDFKYAKDLIAYIRKNYGDHFNIGVAAYPEGHPEEDLDDLILEYLKEKCDVGADF
IITQMFYDADNFILWCDRLRKIGITIPIIPGIMPISTYAAFMRRAKWSEIAIPQHFLDAL
EPIKDDDFAVRQKGTELVSEMCQKLIDSGHIKHLHFYTMNLERSTIMVLERLNLIEPAKS
HEIVGGAELPWRKSLHPSRSKESIRPIFWQNRKFSYITRTATWDEFPNGRWGDSRSPAFG
DIDLCATELLRQSPKKAYDLWGSPKSLQDFSKIIILYLQGDLKSLPWSDGPIGDDSAAII
DNLISLNKKGFFTMNSQPSLNAVESSNKIYGWGPKNGYVYQKQYLEFLCHKDTLAKLLDQ
IDTFNNLKGDNTSSVISYYAVDKLGSLTTNCEEDEINAVTWGVFPGEEILQPTIVERTSF
LAWKDEVYRLFTEWVKIFQSNILEIEKSEADEFVNFITKFSDDFVLCNLVSNNFIDENQT
IFKLIDALETPDL
>C6X8F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylovorus glucosetrophus (strain SIP3-4)|TrEMBL
MDKQELMISVEFFPPKTEEGMAKLREARTQLARLNPKFFSVTFGAGGSTRDRTLDTVLDI
QAAGFEAAPHISCISSSKQEIRDLLQLYQQHDIKRLVALRGDIPSGEVSAGDFRYANELV
EFIRQETGDHFHIEVAAYPEFHPEAASPAADLANFKSKVDAGANSAITQYFYNPDAYFYF
RDECTRLGMDLPIVPGIMPIYNITQLARFSSVCGAEIPRWLRLRLQDYGDDLASLRALGL
DVVTGVCEKLLAGGAPGLHFYTLNQSGIITTLAERLGLKAA
>S4XDE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium terpenotabidum Y-11|TrEMBL
MIVTMCATSPSDPTTENQNAPLPPSLQVAVSDTLKRGTPGRVPFSVEFMPPRDDAAEARL
WSAAEAFHDLGASFVSVTYGAGGSSRERTERVAGKLAMKPLTTLLHMTLVGHTESELRGI
LREFASLGMTNLLALRGDPPGDPTGEWEGIEGGLTHAVHLIELVKSMPECADFDLGIASF
PEGHYRAESIEADTRYTVEKLRAGANYSITQMFFNVDHYLRLRDRLAAYDPVHGAKPVIP
GLMPITSLRSVRRQVELAGCELPRDMEEKFTRIAAGDEQKNAAAIREAGIEETTKMAERL
IAEGAPDLHFMTMNNVRATQEVLHNLGMAPAFGPRFGQDMVR
>A0A1Q8US19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia megaterium|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINVAGVKLAKQAAKDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLNEGVDGLLFETYYDFEELKTVLTLARKETDKPIITHVSLHDIGVLQDGR
PLADALKELETLGADVVGLNCRLGPYHMIQSLEEVPLPDRAFLSAYPNASLPAYVEGKLE
YETNEDYFLESARLFREQGVRLIGGCCGTTPAHVRAMSSALKDLPPITSKVVKMRPAVTV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRTRGEVEGLAIAKNLIDTAYELFDGIYLITPFMRYEMTEILTRYI
HDKQLVTSERKI
>A0A2T2X5V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfobacillus thermosulfidooxidans|TrEMBL
MKTLSQVLQDEGWILGDGAVGTALMDEGVESIALPLVPLRQPDVLMDLHLKYLEAGARLI
ETHTFSANGHKLAALGIDADVVELNRRAAQIARHARDIFGGEAWILGVVGPLAQPVDSQV
MPSVPYEQALEYYRPVVAGLLAGGVDGFIVETMSDLPTVRAAVEAIRSETNLPIAVSFAF
SPQGTTRYGLSPEEAIEAMASLPGGLPALVGANCGSGPAPLLDAIIRMAPKAKELGIPLA
AYPNAGQPGLVAGHVHYPATPRYVATIASALREAGCHVIGGCCGTTAEHIRALQLTLSHA
PEPQVLPSVRDITDASASLDVSHSESHDQGISQFFYKRFIISVELDPPRGVNPHRLLDSA
RVVAEHGADCINIGDSPMARVRLSALATARLISEHLPVQTILHFTTRDRNLMGLQSDLLG
AHALGIRNVLALTGDPPGLGDYAHATAVYDINSIGLVKVLNAFNAGQDALGQKIGGHTAF
DIGVGVNPNADDLNHELQRFREKLDAGAHFVMSQPIYQPEQLERFLDKMGGLPVPLLLGV
MPLVSYRQAVYLHNEVPGIIIGQNILEQFENIQDGTALGIDLALKLMEQLMPLIQGVYLV
PSFNRVEPLLPIIEYLRRQDPWQAKVQGEH
>A0A6I6SLC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas tianxiuensis|TrEMBL
MSTSYPLGISFEFFPPSTDAGREKLIGVRDALAERHPRFFSVTYGAGGSTQGRTLATVRS
IREAGITTAPHLSCIGSEKAQLRDLLAQYREEGIDSLVALRGDLPSGMGGIGELRYANEL
VEFIREETGDHFEIAVAAYPESHPQAPSFERDLENFARKVKAGANLAITQYFFSADAYFH
FVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIVKFG
TEVVSRLCQRLLDGGAPGLHFYTLNQAGPCLRILDNLA
>A0A6G3BJK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5594|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A6I1L103|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMAVAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLA
SEAKVPSAPHLSCVGDSKDDLRGLLTHYKDAGIKRIVALRGDLPSGMGVASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNAESYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EQVISDMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A808FF59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. phaseoli var. fuscans|TrEMBL
MIPTDTPSGASTITDAYSLEVSVKDIGALTNAAPRILPGCAMFIPYLPGQTEAARLAAAQ
MVRRLGFEPVPHLSARRIGSLEELQAFIARLVGEADVTGCLVIAGDPSTPKGPFADSVSL
IETGVFERSGIRTIGVAGHPQGHPIMRTTEQWDVLQRKCRSIQERGMAPLIVTQFGFDAD
IVMTWLEALRARGMTHPVRVGVPGPASVGTLARYAASCGVGACASVLSNYGVSIGKLFGN
AGPDRFVDRLVSRLTEAHGDVRLHLYPFGGIAQSVEWVAHYRSCKASQDRVSSVAAD
>N9DL09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bouvetii DSM 14964 = CIP 107468|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGDHFKIEVAAYPEMHPQADSFDLDIKRFCDKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTDSIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A7H0EWE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cylindrospermopsis curvispora GIHE-G1|TrEMBL
MQENHTTIHTSNSLTSFREAVQAGEFLITAEVAPPKGGDINHTIAMSATLKGRVHAVNIT
DGSRAVLGMSPLAVCAILCQHGIEPICQVACRDRNRIGLQADLMGAHALGIRNILALTGD
PVKAGDHPDARAVFDLESVRLLQLITNMNQGLDFNHRTLVDGGLDLFPGAAVDPQSKSWS
GLQSRFERKVQAGAQFFQSQLITDFEKLEKFMDKIASGYNKPVLAGIFLLKSAKNAQFIN
RMVPGVNIPDHIIQRLAKAKYPLEEGMKIASEQVRMAKDLCQGVHIMAVKKEEAIAPILD
LAGVSR
>N9DQM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bouvetii DSM 14964 = CIP 107468|TrEMBL
MSLLSSYFQQNQFCILVEYLTSLNEIFPAKTQFAGYPAVMTLADRVHSDHDMAPLEASKR
YPLEVEKVLHFAGKGRDIQDFEIFLKQTRAANIRNLLLLTGDKLKEHQNGENTAERSRYL
ESVNAVMAAKKAGGFCIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAQAFLTQHHYAQKILACVMPLSLARAKFMLKHKVAGIVITPHMLNVLEEEKRAGLSER
VYLRCALQILICKQLGFAGIDLSACHKPEEQALLESYVEQYRNLDLNALEKLWKALWRVE
SGKEFQPELSFFSRPPSPSQLIKYHHLHFMHDALFDSKFAKGIGRFIFNSPFWERRPAAK
TLLKTEYISKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARIAKAVEQTQVLKEKLIPAVPIEVRGTSSWKNWYLATEA
>A0A090V512|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudescherichia vulneris NBRC 102420|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDASRNELRAIAQDYWNNGIRHIVALRGD
LPPNGGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A4Q2VC13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. narcissi|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A2N7UCB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas urumqiensis|TrEMBL
MKFEDEPVPGYSLPILPGHVSPGRLERVLRAGKFAVTTEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGAHCHMSSVGVCSLLTRVGYATILQMSCRDRNRIAMQGEILGAAAMGAC
NVLCLTGDGVQAGDHPQAKPVFDLDSMSLLEIARAMRDECRFQSGRRIDLPPRVFLGAAE
NPFVPPIDWRPHRLAKKVAAGAQFIQTQYCFDIERMRDFMLKVNDLGLLEGPDRVFILVG
LGPLASARSARWIRDNVPGVHIPDAVITRLEGSSDQKREGKNLCMDLLHQVRDIPGVSGA
HLMAYRQEHSVAEIIETTGVLEGRVPWYPGRDNPAERNPESMEAEAVQGHSVTDAT
>A0A518N2X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas granuli|TrEMBL
MTPISFEFYPPKNDEQRAQLDRTAARLKAWAPEYVSCTFGAGGSTLSYTGDTVRGLIDRH
GLDAAPHLSCVGGTRDEIAALLERYREAGCRRIVALRGDLPSGMGHPGEFRYAADLVAFI
RAEHGDHFHIEVACYPETHPQAEDALADLRHFRAKVEAGADGAITQYFYNADAYFRFVDE
ARALGVEVPIVPGIMPIANFNQLRRFSEACGAEIPRWLGRRMAAYGDDADSIRELGADVV
SSLCRRLVDGGAPALHFYTLNLARPAMAVLDRLN
>A0A0Q0V363|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. Hv1|TrEMBL
MKITEHIKNAKGKTLFSFELLPPIKGQSIQWIYEAIEPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHAYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMNTDFKYLKKKVDAGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLSQLTVLPKSFHIDLPDELTDALSHAKSNNEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKKIAKAIF
>W2RK30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyphellophora europaea CBS 101466|TrEMBL
MANERLPELIASVPPGETYFSLEFFPPKTQAGFNNLQSRLSRMAVALKPLYVTVTWGAGG
STSSKSLELAEICQRQLGMPTVLHLTCTNMRKSMVDDTLDACKELGIRNILALRGDPPRE
EYREEDASGNRDTGEDEFVWAVDLVTYIRKRHGDYFSIGVAGYPEGHADESNPEAGKQSV
EYDLPYLVEKTQAGADFIMTQLSYDLDAYDKYERRLRTYETASGEKPFERIPIIPGLMPI
QSYQIVKRITKLSHAKIPQDIARRIEAVKDDDEAVKKVGVDILSELVEGIKGLQQPAGLP
RGLHFYTLNLEKSVAFILERCHLIPHMNEPEPDESSDSDAVQDGAHTNGTNAHAPPPSRF
SRRRASSVNAQPHNRVILDSLSGSPGRPRTAQSQDSNGSRHEALDRGTGIPAADPTRKHS
LLISEGQGSLGREATWDDFPNGRWGPAHSPAYGEIDGYGPSLKVGPATARKLWGNPTTPR
DVTNLFSKLITGALTSVPWSDEVDPNAGVNGPGSLRAETQIIRNELLELIERKRYWTLAS
QPAVDGVRSDNEVFGWGPRAEGFVFQKAFVEFFCSKGEWEGLLRKKLIETSPEQLSWMKT
DALGIYESSDTIINAESKQGKPTSKKTPGTNGINAVTWGVFRGKEIIAPTIIESESFRAW
GEEAFAIWGEWRRCYPRGSKEELCLEDLRKDIVLVNVVGQEFVGGHQGRGRTLWDILLS
>A0A4Q5ALD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum subsp. globosum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLTEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAF
IRERRPNMKVYGACYPEKHPQADTLDHDIDNLKRKVDAGVTHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDRWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWANVQDLFA
>A0A5B8XE06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Deianiraea vastatrix|TrEMBL
MSFESKLISSSSFEFFPPLSESGFSALESKIVTCLSLKSAKFASITYGASSSGQERTIAF
VNYFAQKYPALMRKIALHITCTEKTKIEVLQNIKHFYNFGIRQFVIIRGDGNILTNGFQY
ASELIAAARKEFFDIAIYIAGYPEKDNELQYTKMKIEYGVNACITQVCFDAEKLIDFAKK
IKIPIIPGLILPSEKSINFAKKLGVFTCEIPDPKAFLKDQITHLQEGGFSHFHFYTLNNF
DDLLFLFYENI
>A0A0Q9KHL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Soil724D2|TrEMBL
MTIYLGHGSSMRPDNFLVTAELIPPRNWNPRPLVEQAVRYRGYVDAVDLSDNLLAIARLS
PVVGAFFVRQVGVEPIVQINLRDRNRMGIQSDLLGLAALGVKNITILGGYPAKVGTEPNA
KEVYDLETMELVRYVRKMVDEGKLFDGTQMEEAPKFTIGTVENIAGKPIKELIDRLESKV
DNGTNFVRTQLVFDMDLIEEWMAEARRRGLHERASIMASVLPLRNADHVNTALKIPGIVI
PESFHARLAASDSKDEGIAIAAELITQLRRIEGIKGVHIRPIGGAEDSVNNLVKAAGLMP
ITPLSIGALGA
>A0A267GTW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
MPVSQIPRELSAMPENSSSVAKMPAKEKLQQEEQERPQSPQPPSSRQYRPLATRIRRRIE
KGRRWFSCEFFPPRTPAAAVNLVSKFDSFARGRPLFCDVTWHPAGNPAGDSPTSSTSVAS
AMLNYCGIDTVLHLTCVGQTEARLVRVLDRAKSLGLKNILALRGDLPEDADGNPGGASAA
ASGGPAFASDLVRLIRRRYGSFFCIGVAGYPAGHPEAASYAEDLRRLKEKVDAGGEFIIT
QLFFESAEFLRFVSDCRRVGIDCPIIPGVLPVQGYQSLRHIVKLSKLTVPDSMLRVIEPI
RDNDEAIRNYGIAQCTQMCQELLQSGQVHGIHFYTLNRDAATIRILKNIGLWREDLPRPL
PWQPSANYERCAEAVRPVFWSRRPTSYVHRTRHWDDYPHGRWGSECAEIGELRDYYLFYL
TVRASKQERLRMWGSEPTSEPDIWRVFASHLSGKPVSPDGVRVTRLPWGDEEPLPPSSES
NEAAEARQRLAGLSERGLLATNHLLRVNGASSDHPVHGWGGSGGFVYQRAYLEFFLPGRR
LPALQSALSSHGGGRVSFHIADRSGNVNLANFSEPIALTWGVFPASEVAQPTVCDGAAFL
AWRDEAFALWTEEWGRLYEEGSPSRRLIESVAETYLLVALVDNDFTEDSVLWDLTDQVAR
AADGSDEVELA
>A0A2R4M9B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritalea myrionectae|TrEMBL
MNDDLDFVEEFGVNPGDPLTQRPGHVSHGRFERVVRSGHFVVTTEIAPPDSVDPDEVLAR
ANLFDGYVDAINATDGSGANCHMSSLGVCAILTRAGYSPIIQFSCRDRNRIAMQGDLLSA
AALGVCSVLCLTGDDVGAGDHPEAKPVFDLDSISLLQTTKILRDESRFLSGRQLDTAPRL
FVGASINPFVPPLENRVDQLAKKIRAGAEFIQSQYCFDIERLRTFMARACDLGLHEQSYI
IIGVGVLGSAQTARWLRANVPGVHIPDAIIKRLEDAPNPKAEGRRIAVELMQQIKETPGV
SGVHLMAYRHEKWVGEIVKASGVLGDRKPWAPEPLDSTIGVVTPNDEMLDNLTSTVS
>A0A800N7J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium|TrEMBL
QRSGRQAAPHLSCVASTKDSIRKVLRSYQEQGINKIVALRGDMPSGVLSAGEFRYANELV
EFIRAETGDHFEIHVAAYPEVHPQARNGQDDLINFKRKVDAGANTAITQYFYTAEAYFSF
VDDCEKQGIDLPIIPGIMPINNYTQLSRFSEMCGAEIPRWLRKRLETFGDDRESIQALGI
EVVSELCQRLLDHGAPGLHFYTMNQSAPTLRIFDNLHSD
>A0A5N9B5W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MKIIDILNSKKTISFEFFPPKRDSDLPKLHETVDRLSTYNPDFVSFTYGAGGNTRQLTTQ
VSKDAKLSDKFEVMSHLTCIAHNKTEIINILKDLTLSNIENIIALRGDPPKDVTISKDNL
KHATDLIEIIKSNFSNFCIAGACYPEFHPESNNPIDDIKFTKMKQDKGVDFLITQLFFDN
KDFLSFREKAIKLGITIPIIPGILPITSTKQIRRFTKLCGAKIPLKLNEKLENSINNDQE
TTKLGIEYATNQILELIDNDIPGIHFYSLNKTSSVGHVLNNLGISNQTPEYII
>A0A519LKE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEATPGGHSSAMDLVNQINNLGRGKYLHDDQACDEHNKFCIGVAGY
PEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGIK
PIATKKHLKLLPQVFKIDLPEELINAVESAKNNEAVKQIGVEWAISQCKELLDFGVPVLH
FYSMGKSDNIKKVAGELF
>A0A0K0Y361|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Octadecabacter temperatus|TrEMBL
MSSPAISFEFFPPKSVQASFRLRDCVQTLAPLDPTFVSVTYGAGGTTRTLTHEAVDALVK
TSDLNVAAHLTCVNATRAETLAIAKDYKAAGVNHIVALRGDPPKGSDGFRPHPEGFDGSI
DLTRALADESFEVTVGAYPEMHPDASSQQACIDHLKAKIDAGATRAITQFFFEADTFLRF
RDACADAGITAPIIPGILPIENWNGVQKFANSCGANIPQVLQDAFAKAKDPETIDLLATA
QATELCDDLMTQGVDHLHFYTLNKPELTRDICHALGVTPKQSLQNVA
>A0A2W6YHM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFKPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEPSVGGHKYASDLVKQIHDLGIGEYLHGKIESDTDNSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKFFEFVKQAREIGIDVPIIPGIK
PIATKTHLQMLPQVFKIDLPEALINEVLKCKTNNDVREVGIEWAINQSKELLDFGIPVLH
FYSMGKSDNILKIGREVF
>A0A3D4JWN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICASIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHGSAMELVHQINDLGRGKYLHNQDEVCDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGI
KPIATKKHLKVLPQIFKIDLPEDLI
>A0A3C0JKC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium|TrEMBL
MATDLNQPISFEFFPPKSEEGREKLLAVSQQLGQLEPAYFSVTFGAGGSTQQGTIDTVLD
IKNQGFSAAPHLSCVGSTKDNIRKILANYKKHGIDQIVALRGDIPSGTLDIGEFRYANEL
VEFIRKETGDHFHIEVGAYPEVHPQAANAQSDLLNFKRKVEAGADSAITQYFFNVDAYAR
FVEDCKKLGLTIPIVPGIMPITNYAQLARFSDMCGAEIPRWIRKRLEGFADDRESIKAFG
IDVVSELCQSLLEGGAPGLHFYSMNQAEASLTICRHLGFNKG
>A0A522VL61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium|TrEMBL
MFPVSQHFSFEFFPPRDAEAALKLRQAYQRLAPLQPEFFSVTFGAGGSTQDKTTETVLDI
VAQTPIEAAPHLSCIGSQRGNIRAILDNYRSHGVKRIVALRGDMPSGMLSAGDFSYANEL
VAFIRAETGDHFRIEVAAYPEVHPQARDAATDLRNFKRKVDAGADEALTQYFYNADAYFD
FVERARHIGIDIPIVPGIMPIGNFNQLRRFSENCGAEIPRWIQKRMESYGDDAGSIRAFG
LEVVTQLCRRLLDGGAPGLHFYTMNQSETMLALWKNLELPVPA
>A0A5R9NSE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. MHM7A|TrEMBL
MALKNEARGRNIGISFEFFPPKSEEMEGQLWETVSKLQDWEPDFVSVTYGAGGTTKAPTL
STVTRFLAQTPLATASHLTCVGATKEETHQVIDTFRNAGVTHFVALRGDAPGGAGAPYAP
HPGGYANAAELVAGLKEIGNFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGISIPIVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFSGFDD
KPEERAKVAADVAAEQIEDLVRRGIDEFHLYTMNRAPLVSAVLENLGLSRRAIKSAGAAA
>A0A5N9AGW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MRFSEIYTGSSPSISFELFPPNTDKGIKELEERLPKLISLNPSIITVTYGAMGSTREKTL
EIASMIRNRYGVDTAHHLTCVGSSNVEIEKILNDIHDNGIENIVALRGDPPKGQASFVKP
ENGYGHASEMVSHIVNHGGFDIAVAGYPEKHIEAIDLQSDLVNLKNKVLNGANLIITQLY
YDNEDFYRFVSLCRSLDINVPIVPGLMPILNIDQIKRITSMCGASIPVQLLKKLEDASSD
ESKVYEIGIEHTASQAIDLLQHGVPGIHFYVLNRYFHIAEIMDRIKPTLAMKK
>A0A3L6NJ99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. cepae|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A3M9XKV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystis hirsuta|TrEMBL
MFNALHPTASPNQFTISYEFFPPKTPEMETQLWQTINRLAALKPHFVSVTYGAGGTTRER
THSIVARIVRETEMKPAAHLTCVSAAREDVDAILRDYWDAGVRHIVALRGDPPTGVGSKF
EAHPKGYATSTDLVSGIRRIADFEISVSTYPEGHPESASIEQDLDALQAKVDAGATRAIT
QFFFDNDVYFRFLDKARGRGITIPIVPGIMPIRNFKQVAGFAQKAGASVPRWLAERFDGL
DEDPETRALIAATTAVEQVMSLARAGVNEFHFYTNNRADLVFAICHLLGVRPVRERAIA
>A0A5N9DX14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MKITEGCFEATGHTSIICDFSPPRSGDSAVVTQAQIDADFILVAYNPGRAVRTNSAMLAA
AIQQSGKDAVFTLATRDMNKLAVQSLLLGAQLLGLQNVVVVQGDLFGEQDQARVATVNDY
HSTGLISAIVQMNQGQDFKEAKLRTPTDFCIGGA
>A0A5N9E1R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MATVNDYHSTGLISAIAQMNQGQDFKEAELRVPSDFCIGGAVDLGRGIEEEAQLAVRKVQ
AGAEFLITQPIFNVDHVARYRESYAYHAGKAGTLPIYFGLQILEQDGVLFSSVPESVRAD
LEGGRSGVDIALELYQEFQKARLNNVYLMPPIKRGGARNYEAAKEFLTLINKI
>A0A3E1EVL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brumimicrobium aurantiacum|TrEMBL
MKVIDHINEAKDTLFSFEILPPLKGKSIQSIYNGIDPLMEFKPKFINVTYHREEFVYKER
DKGLLEKVSIRKRPGTVGICAAIMNKYHVDAVPHLICGGFSKEDTENALIDLQFLGIDNV
LALRGDPIKTEVTFKPAVKGHKYAVELIEQIQNMNKGQYTMDEIQLEPTDFCVGAAGYPE
KHFEAMNMATDLQYLKQKVDMGADYIVTQLFYDNQKYFDFVKKCREVGINVPIIPGLKPI
SNLRHISFLPKFFHIDLPTELSSELLKCKTNEEVKQVGIEWGIQQSKELKAAGVPCIHYY
TMTNSSEVKQIASELF
>B0CN35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lavendulae|TrEMBL
MAAETAEFPYRARPGRLGDLLRTGQKSYSFEFFPPKTAAGERTLWRAIRRIEAFSPSFVS
VTYGAGGSSRDRTVEVTKRIAADTTLRPVAHLTAVGHSIAQLRHIIGQYADAGIRDVLAL
RGDPPGDPKGEWVPHPDGLRHAAELVSLTRELGDFTVGVAAFPERHPRSPDWDSDIRHFV
AKCRAGADYAITQMFFRVDDYLRLRDRVAVVGCNTPIIPAIMPATDVRQIRRFAELSNAS
FPDELARRLDAARDDPSEGHRIGVDHATAMADRLLAEGAPGLHYITLNRSTATVEIHRNL
GLSPARQPAAARH
>A0A7S3DCV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Palpitomonas bilix|TrEMBL
MKYFLSKQYSNAKKLHTIIEVFKPATREGENSLMERLNRLATLNPALFSISSQNHQHENN
TLSLTQLVREDVCAEVQVHLQCDEPLEILRANIASAKAFNVRHFLFFVLRQPQALVQEGG
EVSHDSVAIEEALKKMRQLLHLLGEEQSIGVMVPYCDTRDEQIWASVARLACPGIDYVVL
PMIATTQSYSARCNLLTKHGVRCPIVPAIVAAALNARSLESLINSTTAGRDEEWQCIVRQ
LLEIEEQIVLSGRTHRLNVHASEQGRDSSSLSAQKSEERASSTLRSFHSTTIHRIKKQKA
EAIQAFWLSRCVELVEGIQECGSPGVYLVSLNLESVVKKVAEACGLREGGTLPWRPRLEA
GQGEQIRPIHWANNPKSYMKRTRGSGNMSCGTWARAIREGDVVFSSHDAGASDQHKSERL
AMWGISLRTHDDVFATFLKYLQRRIRFLPWCDSIAPETDGEIKDTLLKMNSAGFLTINSQ
PAVDAAPSSHPVFGWGPRKGGFIFQKAYVEFFTAQDNLARIVKLCSERENLTYFAANAED
HFVTNCTSSRGTIAVTWGIFPGYEVVQPSIVDRGAFLLWKVRKQ
>A0A806TE02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia megaterium Q3|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINVAGVKLAKQAAKDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLNEGVDGLLFETYYDFEELKTVLTLARKETDKPIITHVSLHDIGVLQDGR
PLADALKELEDLGADVVGLNCRLGPYHMIQSLEEVPLPDRAFLSAYPNASLPAYVEGKLE
YETNEDYFVESARLFREQGVRLIGGCCGTTPAHVRAMSSALKDLPPITSKVVKMRPAVTV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRIRGEVEGLAIAKNLIDTAYELFDGIYLITPFMRYEMTEILTRYI
HDKQLVTSERKI
>A0A8J5L3T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MHLPWCWRLHSLHSGFSLVFGAAALSCCLGFLGGFCYPFCGPVWVCEENISADSRPETVQ
EVPEFLSSVIGNKGFETGHVLGVLLASSPLLEQAWTRCLRANAGSASFVIDKSDDAVFIG
FSRAQAAASPSGLGRGFFEPVSLYSSTHKLFALLGRGEEDSGGKPQPVLLQAPYEEEAQC
AALCKSDKVYMETIMHLTCMNMSVEKIDHALNTIKANGIQNVLALKGDPPHGQDKFVQVA
GGFACALDLLSMEIILVSLLLEAHPDMIQGDEGATLEAYNSGLAYLKRKTLSVVLKFWKS
FSHVKILELCEIFILWSANS
>A0A8E2JEI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lepidopterella palustris CBS 459.81|TrEMBL
MEKVTDKIAALPNNAHYFSLEFFPPKTSMGFSNLQTRLERMSRALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRTLIDDALEQAKTLGIRNILALRGDAPRSEE
YRDEAQLLEGDSNEDFTWAIDLVRYIRKKHGDYFCIGVAAYPEGHADQSHPEHQDPLFDL
PYLVEKTKAGADFIMTQLFFDVEAYDRFETMLRTHPSGVFKTIPIIPGLMPIQSYQILRR
TTKLSHAKLPPDIFARLDAVKGDDELVKQVGVDILSEIVEHIKKSDGSGKRGLHFYTLNL
EKAVAHILERCHLIPILAEEDEEAVAIDYSNNFTPPEGASKARDRRRLSSVNSGPRNRVV
VTRASKSSNASFEAPEDEAGVLKDPVNTRANTLAISEGEGSLGREATWDDFPNGRWGDAR
SPAFGEIDGYGPTLHVPAPQALKLWGYPTTIEDVSSIFRRHISGELDALPWSEEGLNPET
NTIRDELLKLNSKGWWSVASQPPVNGVKSTDPTFGWGPRNGFVFQKPFVELFIPSADWTK
LQQRLDQDDQVTYFAGNNAGHFSASNEESVNPVTWGTFAGKEIITPTIIEAVSFRAWLEE
AFSIWREWQRIYPSRSATAKLLGAIREDYWLVNIIHHAYLDKSALWDFLLQ
>A0A2T2XAI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfobacillus benefaciens|TrEMBL
MKSLSEILHEEGWILGDGAVGTALMDEGVESVALPLVPLRQPDVLMNLHLKYLEAGARLI
ETHTFSANGHKLSSLGIEADVVELNRRAAQIARHARDIFGQDAWIIGVIGPLAQPVDSRV
VPSVGYERALDYFRTAVAGLLAGGVDGFIVETMSDLGTVKAAVQAIREESNLPVFVSFAF
SPQGATLYGVTPEQAIEAMASLPGGPPDVVGANCGSGPAPLLDAIIRMAPKAKELAIPLS
AYPNAGQPGFVAGHVHYPATPRYVATIAPALRAAGCQVIGGCCGTNWEHIQALDAALHHN
LSLLSVPLLNEMSDSGGAGDGGHGETQEQGISQFFHNRFIVSVELDPPRGVNPHRLLEAA
QTVADAGADAINIGDSPMARVRLSALATARLTSERVPIQTILHFTTRDRNLMGLQSDLLG
AHALGIRNVLALTGDPPGLGDYAHASAVYDINSIGLVKVLQAFNRGEDALGQKIGGHTNF
DIGVGVSPNAPDRTQEVGRLRQKLDAGAHFVMSQPVYQAEQLEQFLEEAGSLPVPLLLGV
MPLVSYRQAMYLHNEVPGIVIGQKILRQFENIQDGTALGIDLALQLVEQLMVYIQGVYLV
PSFNRVEPLLPIIQYLRGHDPHSQRDEDRD
>A0A8J5KQM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MKVIDKIRGAANGDGRTVFSFEFFPPKTEEGVENLFDRMDRMVAHNPSFCDITWGAGGST
ADLTLDISNRMQNMKVMYPVYIDLLNSDIDLESALPDRWIVLNEVICVETMMHLTCTNMP
VEKIDHALDTIKSNGIQNVLALRGDPPHGQDKFVQVAGGFACALDLVQHIRAKYGDYFGI
TVAGYPEAHPDMIQDGIATEEAYNSDLTYLKRKVDAGADLIITQLFYDTDIFLKFVNDCR
QIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPDKITNALEPIKDNEEAVRAYGIHLGTE
MCKKILANGINTLHLYTLNMEKSALAIIMNLGLIEESKVLRSLPWRRPTNVFRVQEDVRP
IFWANRPKSYISRTIGWDQYPHGRWGDSNNPSYGALTDYQCVSEVQFTWVNAKFSKFHAV
D
>D1A8T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / KCTC 9072 / NBRC 15933 / NCIMB 10081 / Henssen B9)|TrEMBL
MLPDRPPTIRELLAAGGKSFSFEFFPPKTETGMRNLWRTIRQLEALRPTFVSVTYGAGGG
TRDKTVEIVERIATETTLTPVAHCTAVNHSVAELRHLIGRFAAVGVRNILALRGDPPGDP
TGEWVKHPQGVEYAADLVRLIRSAGDFCVGVAAFPHRHPRSPDVESDTRHFVAKCRAGAD
YAITQMFFRAEDYFRLRDRVAAHGCHVPIIPGIMPVTQLSTIERSEQLSGAPFPPELAAR
FEAVADDPEAVRRLGIEHAAELCQELLDQGAPGIHFITFNKSTATREVYGLLDTGAHRPA
PAPATATA
>A0A3A6P1A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfarculus sp|TrEMBL
MKASTNLEKVLAAGQFALTAEIGPPRGPDAEVVAKKAALLKGLADAYNITDNQTAVVRMS
SIAAAKLVLDAGLEPVMQMTCRDRNRIAMQSDLLGASALGLRNVLAISGDHQRAGAGGKL
KGHPGAKGVYDVDSMQLLAILKGMRDEGLQASGDELTSRPAFFIGAAWTPLGPPKEFRVT
RLAKKIAAGADFIQTQAVYDVKAFAQQLAQAHDQGLTEKAAILPGIIVPRSAGMLTYMHN
NVPGVVVPAELTARLKGASDPKAEGIKVTVELIQAVRELPGVKGVHLQAIEAEELLREII
PAAGLTPRPQV
>A0A357AH82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminiclostridium sp|TrEMBL
MKISELLKEKKKTVSFEIFPPKPEVPLETLFQSVEGFKKLSPDYISVTYGAGGSQQGRTV
EIASRLKNHFGIEAMSHLTCVGKSVDDIDKLLEELMRENITNILALRGDPPADQPDFDFS
KGAFSYANDLIAHIKKGSDFCIAAAAYLEGHADSRRLSEDRRRLKDKVDAGVDFLVTQLF
FDNRLYFDFLEKCAQIHIDCPVVPGVMPIFSARIKNMTAKSGCSIPAKLVLMMDKYQDSP
DDLRKAGEEYAGAMIRELLDGGAPGVHLYTMNKLSSTVKILEAAGLQK
>A0A4R0P5Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter frigidisoli|TrEMBL
MKITDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYNIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADHSFVPTKGGHCYATDLIEHIKNHNEGKFLHEDIETFKSDFCIGVAGYP
EKHFEAPNLNADFKFLKKKVDMGAEFIVTQMFFDNQKYFYFVKKCRENDINVPIIPGLKP
ISTLSQLNVLPKIFHIDLPEELTDALSYAKSNAEAKEIGTAAMIKQAKELMDFGAPVLHF
YTMGRPGQTKEIAKAIF
>A0A1M7T9J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus obscurus|TrEMBL
MSRTVRELLDEGRPTWSFEFFPPKTPEGAAQLWTALRELERLQPSFVSVTYGAGGSTREG
TVSVTERIATETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WVAHPEGLQYAAELVELIRSMGDFSVGVAAFPERHPRSPDFETDVEMFVRKCRAGADFAI
TQMFFRAEDYLRMRDRVAATGCEVPIIAGVMPVTNARQITRIVQLSGQAFPEQLAARFAE
LDGDTPEARAAVRAYGVEVATELCRTLLAEGVPGIHFITMNRSTATREVHANLVAVGAPH
>A0A8D2B330|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sciurus vulgaris|TrEMBL
MNHRKARVLPAGLRYPSLGMWASEAGSVRFSVPPSISRRRAMENLSLGAGGPRPHSEGSS
SGSESSKEGSRCSTPGLDPERRERLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLIARF
DQMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRREEITG
HLHKAKQLGLKNILALRGDPIGDQWETEEGGFSYAADLVKHIRNEFGDYFDICVAGYPKG
HPEAGSFEDDLQHLKEKVTAGADFIITQLFFEADTFFHFVEACTAVGITCPILPGIFPIQ
GYSSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSLCRELLASGLVPGLHF
YTLNREVATTEVLKRLGLWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQD
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELSSEESVFDVFARYLS
GEPNQHGRTVTCLPWNDEPLAAETSLMREELLRVNRHGVLTINSQPNVNGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETTEVLLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSRMIIQHIHDNYFLVN
LVDNEFPLDNCLWQVMEDTFELLNRTAQSGRASDAP
>A0A7W7YRM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella fusca|TrEMBL
MKQATASPARKDIRLSFEFFPPKTAEAEGQLWETAAALSAYAPGFMSVTYGAGGSTKAPT
LSTVRHLLAMGLPAASHLTCVGATKAEVDAVVADFRAAGVRHFVALRGDPPEGVGTAYRP
FPGGYANAAELVAGLRGIADFEVSVSAYPEKHPQSPDVAADIDMLKRKVDAGATRALTQF
FFENDDFERYLERVRKAGITIPVVPGILPVHNLAQVQKFAGMCGASVPGWLAERLAPVDD
RPQERAAVAVELAIRQVEDLVARGVSEFHFYTMNRAALVSAVCDGAGFARIDRAAAAGAA
A
>A0A854QH22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus neoformans var. grubii Tu259-1|TrEMBL
MKITEKLQKAEKEGRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALKEAKSHGCQNILALRGDPVAGTST
WEPTPGGFMNAVDLVRYIHKHYPGDFCVAVAGFPQGHPETPDTPEGRAQEMEWLKAKVDA
GAEFIFTQMFYDTSIFFDWVKRVREAGINAPIIPGIMPIQNWEKFEKWVQRENIIVPSHF
YEALNPVRGDDEKVRQVGTKLVADMCKTILANKEAGIKGLHIYTLNLEKGARMLLQELGF
EGRREQIAPLPWRPSLTPSRREETIRPIFWANRTRSYLSRTADWDEFPNGRWGDSRSPAY
GDLDGYPVSIGITAPDAYNLWGHPTTSFDLHALFARFCRGDLAKLPWSTRPPASETSLII
EQLAKMNELGYLTINSQPAVDGVRSDDKVHGWGPAGGYVYQKAYLEFFVSPDLLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWAHLYPADSPSRKLITDTMNTSYLVNIVANDFRDGMSIFEPFLLDQTAVGKVVEGV
KGTVEGIVEGVKGVVGA
>A0A6I5GNY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID89|TrEMBL
MALGTASTRTDRARTVRDMLATGKSTFSFEFWAPKTEKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVTAAGCETPVIPEVMPVTSVKMLERLPQLSNAVI
PDALKERILAAKDDPTAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A850MEL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Helarchaeota archaeon|TrEMBL
MIIKNKIEHYFFFSQKSGQINLTPDFNGKEIHDPPKFHVGIAGNPNCVPLEAEILKLGRK
IESGAEFVQTQVIYDVELTKTFLKEMERYKFPILIGIFPIESYGVAA
>R9PQX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agarivorans albus MKT 106|TrEMBL
MGFHNAQQIETLNQSLSELNRDINVSFEFFPPTTETMEQTLWSSIERLQTLKPKFVSVTY
GANSGTRDRTHKVIKAIKDRTGLAAAPHLTCIDSTPDELRQIARDYWNSGIKDIVALRGD
LPEGSAKPQMYASDLVALLKEEADFDISVAAYPEIHPEAKSAQADLLALKRKMDAGANRA
ITQFFFDVESYLRFRDRCAAIGIEGEIVPGILPVSNYNTLKKFASFANVKVPKWLHNQFA
GLENDQTTRNLVGASVAIEMVKVLSREGVKDFHFYTLNRSELSYAICHTLGVRPAEAVPA
>A0A1F9WBQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFOXYA12_FULL_57_11|TrEMBL
MRITELLNAGRKIFSFEFYPPKTEEDARRLFDSARELKALNPDFVSVTNSSSGATPYRTV
ALSGVLKAELGLETVAHLTCVAHTRAEINDICLRLKAMGIKNILALRGDIHNHEGAPVKR
EYNYAAQLVADLKKSGDFSIGGACYPEKHPEAETLDADIDRLKEKVDAGAEYLITQLFFA
NDFYFRFLDKTAAAGINIPILPGLMPLTGYKQLENLTKLMKVSVPDVVRAGLERWAGDKE
NLFKFSVDYASVQARELLEKGAPGLHLYTLNRSRAAIDILKNVKARV
>A0A258SR44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium 16-62-9|TrEMBL
MSARTYSFEFFPPKTSEGAEKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETVREIQA
DGSEAAPHLSCIGSTEASIRDILNEYKSQGIRHLVALRGDLPSGTMDAGEFNYANELVAF
IRKETGDWFEIEVAAYPEVHPQARSYAEDMVNFKRKVDAGANAAITQYFFNADAYFSFVE
DARALGVGIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLESYGDDLASIRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPSTVIWQRLGL
>A0A447LVI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atlantibacter hermannii|TrEMBL
MSFFHANQREALNQSLAEVAGRINVSFEFFPPRTSEMEQTLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWENGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFS
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A380MLD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Suttonella ornithocola|TrEMBL
MEDEKQAIVDFVSNYSIELTPKTLLKLGNLHQYLPSTIKVYLTHLPGSDFADTITAVEKV
ITQGFEAVAHVAVRNIRRREALESGLKKLWRSGGRNLLLLAGAGGNVQSPFQDTLAVLKE
GLLEEYDWESIGFAGHPEGHPFVSQEKIKEALLFKQSYAENYPRNYYLMTQFSFTSEPIV
QWAENLEKESIRFPLKIGIPGVASTASLIKHARACGVGASLNFLLRNGGVFRRLIGGVSE
PNLLVRDLAVAKVQKKLPDTTKLHIYPLGGFEATVKWLSAVQSGKFTLEDKKGIQIYE
>A0A258JPK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium 32-34-25|TrEMBL
MKVTQHIENAQGKPLFSFEIVPPQKGSNINDLYVNIDPLMEFKPPFIDVTTSREEYVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGVDAIPHVLCGGFTKEETEYLLVDCQYLNIDNL
VALRGDP
>I5AR70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] cellulosolvens 6|TrEMBL
MKKLAAIMQDKTTVSFEVFPPKTEKGMAKLPDTLEHLYQFHPEYISCTYGAGGNNVGRNL
EVVQMIREADQNTVPVTHLTCIGQTKESIRAQLQAYLDNGVEHVLALRGDIPFGWDGTNS
AFRYATDLVTFIRREFGDKFEIAVSGSPEGHVECTSLASDIAHLKQKQDEGADYIITQLT
YDMEQFKYWYDAIRKAGVTMPVDVGIMPVLKKEPVINQCLSRNACAIPRKLAEIFSHHWF
DTDPEGNELPEVRAAFREEGMQYTVDQILEFISLGVNGIHLYAMNKWQDVTEILNRAGIR
TVL
>A0A4V6LAY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia terrae|TrEMBL
MTPTAPAPSIVERLAAPHRGPVPFSVEFFPPRDAEAESRLWRAVRIFERLSPAFVSMTYG
AGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSVAELRALVGAYADQGITNILALRGDP
PGDPLGEWVAHPDGVEYAEQLVRLIDTLGDFHVGVASFPETHHRSPDIDHDTRTLVDKLR
AGAEYSITQMFFDVEHYLRLRDRVAAADPEQGLKPIIPGIMPVTSLATARRMVELSGSVI
PPDVEERFAKAAGNGAEEDRASVRAVGIDFATEMAQRLVAEGAPCLHFCSLNFAKATTEV
LGRLGVDVDAALHVPA
>A0A359KCZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRSAVNVSFEFFPPKTDAAEANLWAAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVNEVIEGYKAIGVDH
IVALRGDPPGAAGIGGAYTPRADGYANATELTAALSRIGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLKRMT
AACGAALPDWLAGHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAVA
>A0A2T4J8L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fuscovulum blasticum DSM 2131|TrEMBL
MPKAPRISFEFFPPQTLDASFRLWETVQALAPMGPEFVSVTYGAGGTTRKLTHDAVATIH
RNYGLNVAAHLTCVQATRAETLEIAASYADAGVTEIVALRGDAPKGADRFTPHPEGFASS
VELVEALARTGKFKVRVGAYPEPHPDSTGTAADVDFLKRKIDAGATSAITQFFFEADTFF
RFRDQCAKVGITAPIIPGILPITSWDGAKKFATRCGGSVPKKLDEAFTRAIKDGREELYA
LAHCTALCDRLIEGGVEDLHFYTLNRPHLTREVVRALGIQTPVVLEKVA
>A0A7D4P3X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomicrorhabdus xiamenensis|TrEMBL
MQSQKKYAQKLSLEFFPPRTEQGMEKLKTVISEIGAMQPEYMSVTYGAGGTTQEKTLETV
RYIQTQTEFEAAPHLTCIGASQESVLELLDEYEAMGVKRIVALRGDLPSGMMDPGEFKYA
SDLIAFIRERKGDTFHLEVAAYPETHPQARNCDIGIKWFKHKVEQGADSAITQYFYNFDS
YRYFIDNCEKNGIDLPIIPGIMPITNYENLIRFSQGCGAEVPRWLKCRLESFDEDDKEGM
KAFARDVVTELCQKLLDAGAPGLHFYSMNSTQPTLDIAQALTLKNV
>A0A2V4V9P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus barcinonensis|TrEMBL
MKADLRTAMKQRVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVAEVHRRYLDAGTDI
FETNTYSANFDKLSKFGLESKVEEVNRAGVRIAKAVAGTDGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGVPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFAELGARIIGGCCGTTPDHITAIKQALAEYVPLPIAEPDSAE
SQPRIVLHENVDERAGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRALVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDPELIVKMHEATKHLDIPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVTIAKELLDVATEHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A5M8QGC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter flavalbus|TrEMBL
MTKVTEFIEQAAGKTLFSIEIIPPLKGQNINELLNSIEPLMEFKPPFVDVTYHREELIDR
VGPNGLIERIPIRKRPGTVGICARLMERFHVDAVPHVICGGFTKDETEDVLIDLHYLGID
NVLVLRGDPEKSAGVFKAKTGGHTYASELVKQVSNMNQGILLNAETEMSPTNFCIGVAGY
PEKHIDAASMDMDYEHLRKKVELGANYIVTQMFFDNQKYFQFVERCRAEGITVPIIPGLK
PIATKKQLTVLAQIFHLEFPAELASEVEKCASDKEVRQVGIEWGIQQCKELMDYGVPVLH
FYTMGKSDNVAQIAKQVF
>A0A415CJY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AM10-21B|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGNGYHHAVELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTKEILKCKNDAETQQVGIEWCVQQCKELMEHHIPSIHF
YSIGAVDSIKEVAKQVY
>C6R2W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia mucilaginosa ATCC 25296|TrEMBL
MATVHPALSFELFPPRSQASCESLLRTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSNAE
LHRIGVDYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEF
A
>A0A4R3KQH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anseongella ginsenosidimutans|TrEMBL
MKVTDHLKNAKKTLFTIEILPPVKGKSIQSIYDAIDPLMEFKPAFIDVTYLREEFIYKKR
ENGLLEKVAYRKRPSTISICAAIMNKYKVDAVPHLICGGFSKEDTENALIDLNFLGIENV
LALRGDGDKVTGEFVPEPKGHAYGCELVEQIVCMNKGKYLDDELLNAHPSDFCIGVAGYP
EKHFEAPNLKTDLRYLKQKVDKGADYIVTQMFFDNKKYFEFVKACRDFGINVPIIPGLKP
ITTLKQLSTLPKVFYIDIPEELSEEVINCKTNADVCQVGTEWMIAQCKELIDYGVPCLHF
YTMGRSEPTRQIAEALF
>A0A3N1NG55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallaecimonas pentaromativorans|TrEMBL
MSLSHAQHLELLNQSVGELKNDIQVSFEFFPPGTEKAEASLWEALDRLAPLAPRFVSVTY
GHTEEGRVRTHNVIKHISERTGLTAAPHLTCIDTPEAELRQIARDYWQSGIRHIVALRGD
KQPGRQYTNYYASDLVRILREEGDFDISVAAYPEVHPDAKSAQADLLALKKKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIVPGILPVSNFETLKRFAGLTNVAVPNWLAQRFD
GLENDATTRSLVGASIAIDQVRVLRKEGVKEFHFYTLNRAEQSYAICHTLGVRPQLAKAS
>A0A2A3HI79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWS1|TrEMBL
MQKFAFTHCFNKKSCYIIRMSFRKPKNIALELVPRTLDGVLAEARESLSSFPFVTSINIP
EIRRLPIKSFEPSKRLLESGLVTTPHFRLIDRSEKDLLQKIAVLVEAGLSQVLLIGGDPP
KESPDFVPSGLTTLQAVQAVKREFPQLKIYTGLDPYRSSFREELDYARAKRDAGSDGFFT
QPFFSVGMLELWLEQLPDAEIWFGIAPVYTERSQNYWERVNKVVFPPNFSFDRDFNTRLA
RQLLVTISETQQRAYLMPVANGALAYLRDIFEA
>A0A074YB36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium subglaciale (strain EXF-2481)|TrEMBL
MPSDRITDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVNVTWGAGG
STSTKSLALAEMTQRQLGLATCLHLTCTNMSRKLIDETLEQAKSLGVRNILALRGDPPRS
DEYRSNELENNEEDDSNREFTWAVDLVRYIRKEYGHYFCIGVAAYPEGHSDQSHPEHQHA
TYDLPYLVEKVEAGADFLMTQLFYDIHAYQDYEKLLRQHESGAFETIPIIPGLMPIQSYQ
ILKRTTKLSHANLPSEVADRLDPIKNDDEAVKRAGVDILSEMVEALKKNGYPGPKGFHFY
TLNLEKAVAHIVERCKLIGAVNDFVAVEEDDTPVANGKGDKKSKARRRSSLANSAPQNRV
VVDRTRSESCGSATFEVFDDEAGVPGENPPSRADALAISEGEGAMGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDAKDITTIFERHVRGDLDAIPWSEEGLN
PETETIREELASLIQKGWWTVASQPGVNGFRSDHEIFGWGPPGGFVFQKPFVEFFCSHED
WTRLRTKLDKDDQVTYFACNGKGDFQAAEEESLNPVTWGCFTGKEIVTPTMIEAVSFRAW
AEEAFGIWTEWRHVYPPRSPSANLLRNIRDNYWLVNIIHHDFTESNGLWKMLQEA
>A0A8A1MHZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces capsulatus|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNILALRGDPPREKEK
WEAIEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDDQDDPDLLMQHLKEKVDAGGTF
IITQMFYDVDNFLAWVNKCRDNGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEAL
EPVKNDDVAVRNLGKSLVANMCRKMLAAGIHHLHFYTMNLQQATKMVLGELELIPSHKTP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSLKELSEIFVRFLNGNLDRLPWSEGAVTEETDVIKLDLLD
LNRRGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNP
DLTYYCVNKIGELRTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHGASSPSRRIIQQVMDNWYLVNIVNNDFHKTHDIFNIFKDLKVENLNVQVEPIAQAAE
LVDNAQENSQDPQKQVNGSSTEVTESKQEISSN
>A0A1Q7XU89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_20CM_3_58_11|TrEMBL
MKIYDFNERLKDSILIADGAMGSMLHEAVGFERCFDELNSTEPEAVFRIHQAYIEAGAQI
IETNTFGANRFKLAPLGLAEEVQRFNSRGVKIAREARESAAREVLIAGSIGPLGLGVQSR
HPSPEEIQEIFHEQALALEERGVDFYILETFSYIEEVLLAIDAIRSFSGLPIVAQLTYAE
EGTTYGDVRPSDAAAQLKNKNVQVIGANCTLGPQALLPILEELAAVDGLRVSGMPNAGFP
KREGDRIVYPRSSPEYFALFAREAAALGVRILGGCCGTTPAHIRAMAEAVKLLRPSETHP
VVRSVETVLRPVPVARREPESRFWKQLQKKEFSVCLEIDPPKGLSLDRIFEQVDKVMASK
KVDAIDINSGAMARVGMDALIVAGALEARGIETVPHLTTRDQNIIGLQAALLGAWTVGGV
RNVLAITGDPPSVGDYPETSGVYEVDSVGLVKVLNRLNQGTDWAGKTLGGATNFTIGVAV
NPVADDLDNEIERFHAKVEAGAHFAMTQPLFDPQHWHAFLNKLGGKPVIPVLIGIWPLNS
YKQALRLSNEVPGIVIPEPLLKSMEAAGSAARDRGFEVARDMLAWARTELAGAYLIPPFK
RYEEILEIL
>A0A1G7A1I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas thiophila|TrEMBL
MARPPFLEALRQGVLLADGAMGTLLYSQGGDCSCFEALNLREPQRVLAAHQAYRQAGAGL
LETNTFAANRHQLGLSGLADAVAEVNRAGAALARQAAASQVGPCYVAGAVGPLGPAWYER
EPPEQASAALFREQIAALVAGGVDLLLFETFARLDELLLALRVAREFALPRVAQMAFVAE
GRTRDGLSAADIVRQLRPLADVVGTNCGCGPHDMLQRVREMAVVDDGLLSAFANSGFPQY
VNGRHLYLATPDYFAARGGEMVAAGVRLIGGCCGTTPEHIAALNRTLQRPLPVRSVSSSV
VPVTPVPTAAPVTSPLLERWAAGRQPITVELDPPRGLDCSAVLAGARRLAAAGVDAINLA
ENPLARIRMGNLALAARIQEASGVPVIAHVTCRDRNLIGLHSELMGAHLLGLRHVLAVTG
DPVAVGDAAGASNVFDLNAIGLLGLLAALNQGRTLLGSELGGHTAFCCGAAFNPNAQPLE
GQLRKLERKVAAGARFVQTQPVYSAEVLQRLRELSGHCPVPLFVGLLPLVSERNAEFLHN
EVPGIRLPDVVRQRMRGTQGDSGVAAGMAVMDELIGQMRGWVAGYYLMPPFGRVELAEEL
IHRIRAVA
>A0A511DN45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sulfidoxydans NBRC 16205|TrEMBL
MTVRDLLATSVLVGDGAMGTMLHAAGNSLDQALPALTLTEPGLVRTIHDSYVGAGVDLVQ
TNTFGASRLRLAEYGAADDVARINAEAARLALEAAARADRPVFVAGSVAPAVSVHQRRRV
GAEERRAAVREQVEVLVGAGVDVVMLETFGHLDELVEAAEVALEVARRTGDVPVVAQATF
GTDHHTLSGHTPHELVTALAGLPLAAVGVNCTLGPQGCLAVLRELRSHTALPLTVQPNAG
LPRRVAPARFEYDIDAEYFVRYTRQLLDAGAALVGGCCGTTPGQLAAAAAAVAEYRAQQP
VTVVEPSRSLPVPPARPELFDAAGPLIGVELAAPTTGGVDESVALAAELREAGVGLVCVP
ASSGPRAQVNSVDLALHLHDRLGVTTLASVTTWDRTIMALQADLLGAHALGVRGVLCETG
TPPLVGDYPHVDGIWDVDSLGLIELLAGLNEGTDYHGLRLGTKTSFDIGARVNPGSRDPG
RAAAGALDKIAAGAQFLITRPVYEPAGLERVVEAVDGRVPVLVAIRPLTGFDEADYLAHE
VPDVTIPDATLAALADAGPDAAAAGVDLALALAEQVRTMTRGVVVTGGSDVAATVQRLRR
L
>A0A3S2FCB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.09.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A4R0EJ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter terrestris|TrEMBL
MTKRVPISFEFFPTKTDVGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGNHFTIEVAAYPEMHPQADSFDKDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A6J4NV13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Phycisphaerae bacterium|TrEMBL
AHRPHARPRQARDLVRVLPAEDRRRVPEPVRDGRGPAAAQAVVRLGHVRGWRLHPREDRR
PDRPHPEGPEHPVDGPPDVRRAHGRRDRVDPRRPRRRRRPQRVGPAGRPAGRAERVRQDR
GRVRVRQRAGRVRRHPARLLRRRRRVPRGAPAVPEPHPRLGEPAEEGRRRRAGGHHPVVL
RQRRVLPVPRRRPADGGHGPDHRRDHADPERVADQAVHRHVRGEDPAPAARAARGVRARR
RQRLQGRRRLRDRAVRRPA
>A0A0S8FLI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium SG8_31|TrEMBL
MNTAPLVSFEFFPPANEAMEQRLYTSVRRLAPLRPQFVSVTYGADGSTRERTHRVVERIV
SETDLVCAPHLTCVGASRAEVLEIARQYADMGVRHIVALRGDPPEGAKSYRPHPDGFAYA
SDLVEGLKTVSDFEITVAAYPEVHPEARSPLSDLENLKRKIDAGASRAITQFFFDNDCYL
RFRDLCVAAGITVPIVPGLLPITRFPQLLKFAGRCGASVPEWLCKRFEGLDQDPETRQLI
AASVAIEQVQFLRRHGVEEFHFYTLNRSELTYAICHTLGLRSAPAARSA
>A0A367ILR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus stolonifer|TrEMBL
CVDWIHKCKEKGIHVPIVPGIMPIPTYQSFRRMIHLCNVKVPEKVMQDLDAIKGDDQKVK
EYGVQLAVDMIKKLHTEAGICNFHISTLNLERSTRLILEELQLHKQQTNKIPPWAPVHDP
ARAELWDEFPNGRYGDSRSPAYGENTYGAGQILPTSDASSKWGQPNHENDITELFVKYIR
GELDSLPWCEERLHTESEAIRQRLTDINQRGYWTVSSQPAVNGVPSEDKIYGWGPKGGYV
YQKAFLEFFVSDQHIKELLARLYKDSSITFYATNLKNAVTWGVFPGKEIIQPTIIEKASF
EAWKDEAFGLWKEWEEQYPPGSSSQKVLEEIRQSYWLVNVVHNDFQKSDLLFNVMLA
>A0A7Y0PM62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niallia alba|TrEMBL
MSFLDRLKNEILIADGAMGTLLYSYGKDTCFEALNLSHHEQIQHIHQAYIHAGADIIQTN
TYAANYLKLQRYGLEDNVKEINSAAVKIAKQAATTNKVNILGTIGGNRGMKPQAISLEEL
KRSFREQLYCLLLEGVDGILLETFYDLEELETVLQITKKETDLPVIAQVSIHEIGILQNQ
SSLSSAFDRLENLGADVIGLNCRLGPHHMIASLEQIPLPKHAYLSAYPNASLPTYIDGKF
EYKDNAEYFRKSAEEFRKQGVRLLGGCCGTTPEHIKNFAEALKDAVPITEKAIPSNANAL
RVESILLNSPPLREYTPLEEIAKERASVIVELDPPRKLDTTRFFEGAKKLKEEGIDAITL
ADNSLASARISNTAIGTLVKQNIGLRPLIHIACRDRNMIGLQSHLMGLHTLGLQDVLAIT
GDPARVGDFPGASSVYDMTSFDLISMIKQLNEGLSFSGKNLGQKTAFSVSAAFNPNVRQV
DKAVKRLEKKIECGADYIITQPIYSEEKIIELYEATKHIDKPIYIGLMPLTSSNNAEFLH
NEVPGIKIDDSIRQTMANLKDNPEQATQEGLKITKSLIDTAATYFNGIYLITPFLRYELS
VELARYTKRRTAATRRTTNATNFIS
>A0A0K0E3L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strongyloides stercoralis|TrEMBL
MAPNLDDTKSTEVKFNIDDDLKLRRNTSSVYSFNDENEVTTYTPLIKRINNQIESGVPFF
SLEFFPPKTANGVANFINRLDRFRDGGTFFLDVTWHASSDPSNLDKDTSSTSIARCVLDY
CRIDTMLHMTCTQYTKEQTLSHIKQCKDIGLRNILALKGDLFIDPNVPEEERPKSKYYAL
DMIKWIKEYYGDYFTIACSGYPLGHPSGESYTSDLQYLKAKVDAGADFIITQLFFEVETF
EKFVKDCREIGIKVPILPGIMPIQGYASIKRIAELSNLLIPQSILDDLEGIKHNDEAVLK
YGIDRAVKMCQYILDNNIAPALHMYTMNREGPTREILQNLGLWKHYQIKSLPWKPHGGHH
PLRCKEDVRPVFWSARPKSYIFRTREWDDFPNGRWGHSSSPAFNDLKEYYMFYLNVSNKE
KELQMYGDKLYSVEDIQKVFVNFLKQQKNENGVKVTCLPWNEDEGGISFETNLVKDQLIW
ANNNGFLTINSQPNVNCASSSDPIVGWGKQGGYVYQRAYLEFFTKKENAQKLIDIINLRY
NERINYHAIDRTGMYEMFNYNGTNPIALTFGIFAGSEIAQPTVVDPLSFRVWKDEAFDVF
NIWSSIYPPESKCRETLKFLHDNYILMTLVDNDYVKPTIIFDLLNEVVSM
>A0A0M4G1M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. FJAT-22090|TrEMBL
MGLLEKLQTNVLTADGAMGTLLYSYGIDYCNEELNIQKPEIIEKIHQDYIVAGADIIQTN
TYGANAIKLARYGLENQMKEINEAAIQIAKRVAAPGGQFVLGTIGGIRGIRKSDATIDEI
IETVNQQATQLLSGNPDGILLETYYDFEELSATVTHLRKLTDTPIIAQVSMHEPGILQNG
LSLNDALHQLEALGASIVGVNCRLGPHHTIQAFEGVTLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGKAALYLREAGVRLIGGCCGTTPKHIEAVKKRIGTLPPITNKIVTPRKPII
IQEAEPTVNQPLHEKAKTERTIIVELDTPRHLDTTTFMEGAEKLNAAGIDAVTMADNSLA
SPRISNMAMGSMLKLQNNIRPLAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKI
GDFPGATSVYDVSSLELLQLIKQLNEGVSFSGKSLRKKANFSVAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVYSKEKMEEIYEATKHLSTPIFLGIMPLTNSRNSEFLHNEVPGI
KLSDEVLERMRACGEDKERSTAEGIQIAKELIDTAAELFNGIYIITPFFRVDMSLELIRH
IKEIDGKKARENSYVQTSN
>A0A7C7EJE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MRHHIQNKIYHVEILPPKQDSEKLEADLELFANKYARVMESGYCACITDNAMGNLAFQGT
EMIQELDLPVYPEQVMIHLNTFHTKENLDEILNTCIEKGIKYLLVVSGDGSERLPKLKPS
DIGAEGVESVTSVELLKYINREYKDKFVLGVAFNPYEPEDHEFEKMERKIAAGATFIITQ
PIIEKNPVVDKLLEKYPDVPVIVEAWMSKKLHLLSDAVGYTIPETTEYDPIATLKMLHKI
YPKCGVYLALLGFKTQFDLIKDTWVSE
>A0A3D5R6S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKICEKFKIKKPLVSFEIFPPKMGYSIDTIYDTIDELYNLDPDFMSVTYGAGGSTKDRTV
EISSYIRDKYSLDSIAHVTCIDSSRKEIENTLKSLEEKGIENVLALRGDYPLNFDKNSLP
ADSFKHSTDLIRFFKENSDLSIGAACYPEKHPESPNLETDLKYLKEKVDSGADFLVSQMF
FDNEIFYDFMDKLEKKQISVPVIAGIMPILNKGQIKRIVSLTGNTLPNKFKRLLERYEDN
PEALNEAGLSYAIGQIIDLLSWGVDGVHIYTMNKPETARSIMESMKAIRGVLTNGKK
>A0A256ZNZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon ex4484_2|TrEMBL
MSNLLKRLGKKFIYTTEIIPPRTADLKPLDKEIKKINSRITSVFVPDLPGASLYMNSLVY
SIHLKNKGLEPVYQINCRDRNSLAIESNLLAAHASGIVNVSAVTGEHPLRGDHRGLKTVY
ELDSMTLLKTIDYLNNGRDIAGNKLIKKTGFYMGSDLSIHSKPAAAQMYKTRKKSTVGAR
FFHTRPVYSMNKLKKFLDEYRKLFGEDLGGKTIVGLQSLTSIEQVNFLRKQPNHSIPTKT
VKRIRESDNPREEGIQLTLEWIDKIKELNPAGVHLFSGGDAELTGEILNLD
>A0A316MCW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MHLNELPRPFVFDGAFGTYYAARSRGDAPCEAANLSDPETVVQIHREYIAAGAQAIKTNT
FSCNAVTFPDASELTRLIQAGFANAQRAAEGSEVSVFADIGPIPDGESGDYLAVAEQFLA
LGAEYFLFETQPDLDPLPPVFAAVKARAPQAQIIVSFAGAQDGLTRLGRSCAQLLRQAAA
LDTVDAVGLNCICGPAHLVRLVREALPLQKPFSAMPNAGYPSVFGGRTVYIDNAEYYAGK
LSELAHLGCAIVGGCCGTTPQHIRAFTDARHGIQTPSAAAGTAVQSAVPVSRPNPFRAKL
SLGSRKVVAVELDPPHDNDLSPILEAAKQMKETGVDVLTFADSPLSRARADSMATAAAVC
MNAGIPVMPHLACRDRNQIAIKGGLLAANALGVSNLLAVTGDPLSDTDRSGVKSVFSMNS
YGLIRFVDELNQSAFASNPFFIGGALNLNTLRFDVELDRARKKREAGAQFFLTQPVFSDE
AAEHLRMAHETLDTKILAGIFPVASYKNALFLTNEVAGIEIPDDFLHRLERAAPEEIPLL
SAEFALEMAKKSAPFCDGFYLMTPLKRFDIVRLLAERILASLC
>A0A2P7SPL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium ephedrae|TrEMBL
MIERRSVQRDENPAGIHLPLEPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLG
AAAMGVSNILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPYDFRPLHLGKKIAAGAQFVQSQYCFDVPMFRDFMQRVRDLGFDEKVF
ILVGVGPLASAKTAKWIRSNVPGIHIPDAIITRLEGAQDQKAEGKKLCIDIINEVKEIPG
VSGVHVMAYRQEEYVAEIVDESGVLKGRQPWKREARADDQRVAERLGHILHDDVTETQVD
MVKTAH
>A0A2S4RSA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter amalonaticus|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A061EJJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Theobroma cacao|TrEMBL
MKVIEKIRTLQEEQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGSDGVATPEAYQNDLEYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPADITNALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRFLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSQN
PSYGALTDYQFMRPRARGKKLHEEWATPLKSIDDLLVSTSI
>A0A222P7S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia sp. oral taxon 498|TrEMBL
MKIKDILEKKEHTVSFEIFPPNKNFSEEKLKNVTAELVQYKPDFISVTYGAGGKTKSGTI
EMASHIKNNLKTEVMTHLTCVGSKKSEINNFLKEVKENNIDNILALRGDVPVGETEEIYD
RGDYKYASELISDLRQNEKFSSFSIGAAFYPETHYQNNDLVDLFHLKNKVDSGVDFLVSQ
MFFDNDLFVKFRENAEKLDINVPLVAGIMPVTNAKQIKRIIELSKCSVPKKLEKLIEKYG
DNPDSMRKAGIMYASEQIIELFAYGIKGVHIYTMNKAENAKEIIKNIAFLR
>I4YDE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66)|TrEMBL
MKIVEKINESKDNKTPFFSLEFFPPKTDQGFVNLKSRLQRLSLLKPGFVSVTWGAGGSTD
ERSLELAAVARDLGLDVLLHLTCTNMEKSRLSWALDKAKELGIDNILALRGDPPRGHEYW
VESDKNLSHSSDLVKFIRDNYADNFCIGVGAYPESHKDSSDAAQDLKYLKLKQDLGADFV
ITQLFYDSDAYLNWLDKCLDIGIKIPIIPGIMPIQNVPSLRRLANLCGAHIPSVISDHLE
PIKNDDALVKDYGVELSTSMVRQLIDKTNSQKEKYGNLAISAAHFCTLNLEKSVRRILAN
LDWSSGLDASSLEPNGLTHNTTTGAVEPARLGNRLVAENGISHGHTADGPPPLSITAHEA
AVRALHALKHHPPSEDSGLPSSNKTSSGGNSLWDEFPNGRYGDIRSPAYGELDGWGASLK
LSSQNALKQWGYPVEVSDINEIFKKYINGQVASLPWFEENLDPESNSIKDYLFRLAEKGW
WTVGSQPAVDAVESSDQIFGFGPKNGWIFQKAFVEFWVPEHELEGLCKRLDGWKDGGYYA
GNAKGEMKTNFYEDTINAVTWGIFPGQEVVQTTIIEDVSFNAWREEAFEIWLEWSMLYSP
KSASQQLMKNVHDNYWLVSVVHHDYKDTNGLWEFLLS
>A0A2H0WEI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrio sp. CG10_big_fil_rev_8_21_14_0_10_47_8|TrEMBL
MKVIEHLEKSRNPLFSYEIVPPPRGRSVKDLIDVVEMLSPYEPPWIDVTAHSSVAFYNEL
ADGSIQRKIMKKRPGTIGICGIIQNRFRIDTVVHLLCQGFTREETEDALIELGYLGIENV
LALCGDYLNFQKPIAKDRTSNKYAKDLVTQVTDLRRGQYLEEMSATAALDFCVGVAGYPE
KHFEAPNLKTDIEYMKQKVEAGADYIVTQMFFDNSKYLSFLKQCRDAGITVPIIPGLKVL
RSVQQLKSIPKNFYVDIPEPLSDEILKNPTHAAEIGKRWALDQVEELFANKVPCAHFYVM
NDASLVVDIVKKFK
>A0A1M5YX29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio fibrisolvens DSM 3071|TrEMBL
MKIIDIFNEKEITLSFEVFPPKTDAGYEAVEKASAEIAALKPDFMSVTYGAGGGTSKNTV
NIAANLQDKYGVNVLAHLTCVSSTREHVKSMIASYKERGIENIMALRGDIPKEGRICDDY
HHATELIYDIKSMDENFCIGGACYPEGHVECERQSVDIGHLKEKVDAGCDFLTTQMFFDN
AILYQFLYRIREKGINVTIVPGIMPITNAKQVSRSVALSGSTIPQKMKSMVDRFADDPQK
MKEAGIIYACDQIIDLICNGVGHIHVYSMNKPDIAAGIMRNLETIIK
>A0A8H9WJN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGKLAKALKSSSFVVTSELTPPKGTDLDELFAKADLLRDLVTAFNLTESHAARMAMDPVA
VGHLLIDRGIEPIVQMTSRDKNRLAIQASILGAAALGVSNVVFMGGDPPKNGDHPDAKPV
FDLFASQLLEAACALNNGTDLSGNALKGTPQLTIGAVANPGASDLALEIDNMKRKADAGA
EFFQTQAIYDVAAFDRFMTKAKPERPVLAGIIPIKSVKMAQYMNDKIPGVDIPQDLIDKI
DAAGDDKAKVADISIVIASNTVRELRDMTRGVHVMAIGWEDKIPAILDRASA
>A0A7C7S7Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSSLADKLRSGQFVITSELSPPKGTDTSALEATAALLSGHIDAFNLTDSAASKMSLSPLA
AASILLKHGVEPILQMTTRDRNRIALQGDMLGAWVLGVKNLVCMGGDPPHLGDHPEAKPV
FDLSTEELILAAHKLNNGTDLMDNPLNKSCDFHIGAVVNPGADDLGKEIARLESKVEAGA
RFFQTQAIYDADGFATFMAGISHLDIAILAGVLPIKSVAMATYMNNKIPGICIPDALIER
VAGATDIVAESTTIAAEIIRAISPMCQGIHLMALGGEKHIPAILAQL
>A0A661CBT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAISADYLAGVFRPQNEIRNALRKGRFFWTIEFVASSDHVLNDDLVTVDSFVRALARRPE
VAGFSVTDRVHSDDDPDPVMMAKHIRDHAGTQPLVHWSGKDRSITDFESSLEAMSAAKLE
NMLLLTGDKLKITPVDRRPRYLESVAAIKLAKDNYPDLIIASALNPFKYREEEAMAQYLK
LGKKIYAGTDFVITQIGFDIKKFEEALFWMDTRDYRVPMVANVMALTAARSRFIRKNQLA
GVTITDSYHEFLQQEAELFPEQAPARVLRRTALLILGLRMLGYSGVQLTAIHTVDQLMTL
HKQIDYLAKKCPDRVSWNKAWQESLTLPKAFIANPVPGKAWYMSSHMVNRPSSHAPLKDR
IKYRTMKWSHSFLFDQGLGAKVLSGLVKNIQRHSKADKILERIERLIKAPLFGCETCGMC
RLAETQYICPETCPKGLANGACGGTNDNTCEFGDRECIHSRKYRIAKDANVLSQLEHWLI
PAVPDEARQTSSWPPHFRDEGPDIDKSGMDKPEPDISSDE
>A0A6N8XD28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPQFSFEFFPPRSPGGRANLVATAGQLSRFRPQFYSVTYGAGGSTRERTYEAVATLRDAG
INAIPHLSWGGVDADDVIALLHRYLKLGIDRIVALRGDVPSGAGSSHQFRYADALVRLIR
ARIDAPLYIEVAAYPEVHPDAPSASRDIEFLKRKIDAGADGCITQYFYNAEAYFHFRDRC
AAAGVDVPIVPGVMPITNYDTLARFSAKAGVDIPRWLERRLDEIGEHADDLLGFSTDVVS
TLCQRLLTGGAPGLHFYTLNKAPPTEAIAERLVP
>A0A7C7TXL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSRSELEQVLRSRQLAVTAELSPPDSADPQEVYKRAALFAGHVDALNATDGSGANCHMSS
VGVCALLTRAGYSTVMQISCRDRNRIAIQGDILGAAAMGVRNILCLTGDGVQAGDQPDAK
AVFDFDSISLLETVRYMRDESQFLSERKLSTPPDVFIGAAANPFSPPVDYRPQRLKKKIE
AGAQFIQTQYCFDVPGLIDYMSEVRNLGLHERCFILAGVGPLASARTAKWIRENVPGVHV
PDHLITRLEGAVDQQQEGVKICIELIQQIKEIDGIAGVHVMAYRQEEMVAEIIQKSGVLN
GRSPSVPSMLRDL
>A0A7C5Q161|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAVKISCEFFPPRTEAGVEKLQLVQQKLNEVMQPEYYSVTFGAGGSTRDSTLEIVKLLVK
EEINVAPHISCVGSSKQQLNDLLIEYKNLGVTRLVTLRGDIPDTGETTKELSHANELVSF
IRETTGNHFTLEVAAYPEYHPESTSPQSDFECFVNKVNAGADGAITQYFYNIDAYDRFID
NCLRENISIPVTPGIMPITNYRNLSRFSDTCGAEIPRWIRKQLEAYADDKASLQAFGLDV
VSRLSNQLLERGAPGLHFYTLNQAEASNAIWKNLSL
>A0A510P2U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida auris|TrEMBL
MKISKKLEHAHSCSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYELNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALKKAHASGCQNILALRGDPPLD
GSESTGDFKYAKDLIRYIRKNYGDHFNIGIAAYPEGHPEEEDETKLLSYLKEKVDAGADF
IITQMFYDVDNFISWCSKIRKIGVEIPIIPGIMPISTYSAFIRRAKWSQIKIPQHFLDAL
DPIKEDDYAVREKGTALVGEMCQKLIDSGYVNHLHFYTMNLERSTIMVLEHLNLIEHVKD
NAVVGDELPWRKSLHPMRSKESIRPIFWQNRKYSYISRTSGWDEFPNGRWGDSRSPAFGD
IDLSATELLRQSPKRAYELWGCPQSLQELSQIMISYLKGEIKSLPWSDGPIGDDTEVLKP
ALIEMNTNGIFTLNSQPALSAVKSNHEVFGWGPKNGFVYQKQYLEFFIHKDLVHTLLNRV
EAHNAKDAHSVITYYAVDKSGSLLTNAHDDDINAVTWGVFPGEEILQPTIVEKISFLAWK
DEVYRLLDEWVKIFHTKTITELVEEDKINAFSRLLTSFGDNFVLCNFVNNDFTSGNNIIF
DLFDGLQVSSL
>A0A3D5FGM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MHRQPRVSFELFPPATPAGWAGFVDTVDQLDHLDGAFMSVTYGAGGTSQERTLRALEAMT
ACCTTPVAGHLTCAGSNRTEVMTVVDAYAAAGVKHIVALRGDPPRDSSAFQPPPDGFPSA
AHLVSAIAQRGSFDISVAAYPEVHPEAASLADDLDNLKRKIDAGARRAITQFFFEPDTFL
RFRDQAAAAGIHVPIIPGILPVVNLKRTIEMASTCATHVPPWLTSLFDGLDDAPEIRALI
SATVTAELCTRLQDQGIDRFHFYTLNRPELAWAICRMLGLRSTSSHSGYIQTSVASA
>A0A2E3YPN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSINIRVSFEFFPPATKKMSETLWRSIKRLEPLXPNFVSVTYGADGSTRDRTHQVIERLQ
KETSMICAPHLTCIGAPREEVLAVAKDYWKTGIRNIVALRGDPPKGTKIYRPCKGGFDYA
VDLVKGLRTIGDFDISVAAYPEVHPEAKNAGXDIDNLKRKIDAGASRAITQFFLDTTAYL
KFRDHCHAINLGVPIIPGILPITNFSRLLEFAKDCGAFVPPKLHEQFSGLDEDPDARRMI
AEKVAIEQVEELKQHGVDEFHFYTLNRSDLTYAICHSLGLRPTQKTKEQ
>A0A351CLN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTSFEFFPPQSEKGKDNLQQVIKQISKINPEYFSVTYGAGGTTQESTFETVIDIKNNNK
VRVAPHLTCIGASKNITKSILDKYKANGIDKVVALRGDIPSGMQNTGELRYANELVEFIK
SEYDDYFHIEVAAYPESHPQATNIGTELSNFAQKVRAGADGAITQYFYNPDAYFRFVDDI
EKLGIDIPITPGIMPITNYSNIVRFSNMCDAQIPKWITERLRLYRDDKESLLAFGEDVVL
KLCQTLIDNGVDSLHFYTMNRSEPIMNIIKKL
>A0A1I5A8K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius lutimaris|TrEMBL
MKTPRISFEFFPPKSLEASFRLWDTVQTLAPLEPRFVSVTYGAGGTTRELTRDAVGTLHK
ATGLNVAAHLTCVDASREETLEIADQFAAAGVTEIVALRGDPPKGSDGFAAHPQGFGNSC
ELISALAETGKFNIRVGAYPEKHPEATSQQADIDWLKRKIDAGASEAITQFFFEADTFFR
FRDACAKAGIDAPIIPGILPIENWTGTRKFALACGTQVPAWLDDAFDKAIRDNRHDLLAT
ALATELCSDLIEGGAEDLHFYTLNRPELTRDVCHALGVTPKVELRHVA
>A0A1F8NYI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_48_8|TrEMBL
MQTALKNGEFVVTTEIVPPAGINTATFAESAKRVENHVHAINVATNPMATAHMSSLACSL
LLKDMGIEPILQITARDHNRLSLQSEMIGASALGIRNVLCLTGDPPKAGRVPFQGLPFDL
DASQLLWILRRLRDDARFLDGRKLDDHPKFFLGAAGSPNDPNPTHEALRIEKKINAGAQF
LQTQLVYDLSDLEQWLEALDARNLLSKVYILVGLAPLRSLEHAIFLEEKIPDVTIPPHFI
NRLKQSSCPEKTGLEITQELFQQIKELPGVSGVHLMSIGGNEILPQMLEGIDFDLQKTS
>A0A523KHS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSDIGAFEKLLASGQFAVTAELSPPDSADPEEVYSRARVFDGYVDAINATDGSGANCHMS
SIAVCSLLERRGYTTVMQISCRDRNRLAIQGDVLGASALGISNVLCLSGDGVQAGDHPGA
KPVFDLDCMSLIATLRGMRDESQFLSGRAISTPPRILIGAAANPFVPPFEYRVERLAKKI
SAGASFVQTQYCFDIVRLKEYMGRVRDRGLHEKCAILIGVGPLNSPRAARWMRDNVPGVH
VPDHVIKRLEGAERPRLEGRRLCMEMIQQIREIEGVAGVHVMAYRQEEAIAEIIDASGVL
DGRMPWNPAGQPDLPLQRAIL
>A0A6A1R6P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas kerstersii|TrEMBL
MPTACREGRPGVSNVATAFPISFEFFPTKTPEGAAKHVQVRKDLSARNPEFCSVTYGAGG
STQAGTFSMVRDIQAEGMQAACHFSCIGATSEKVRSELQQLKDMGVKRIVALRGDLPSGY
GLGGEFHYASDLVAFIRKEFGDWFHIEVAAYPETHPQAKSPDADLRAFATKIQAGANSAI
TQYFYNVDAYLRFVEGIQALGVSVPVVPGIMPITNSSQLMRFSDATGAEIPRWIRLRLQA
YGDDVASIRAFGLDVVARLCEQLRANGAPGLHFYTMNQSAFTLELCDRLGL
>A0A1S8DIQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopseudomonas pachastrellae|TrEMBL
MTNRNIPINFEFFPPKTEAGQAKLVAVANVLADEQPEFFSVTYGAGGSTRDGTRRTVLQL
NNEVGVPAAPHLSCVGDSREDLRTLLNDYRAQGIQRIVALRGDLPSGMGHASGELRYANE
LVEFIRAETGDHFKLEVAAYPESHPQAPNFETDLKNFIRKAQAGADSAITQYFFNADCYF
HFVDRVRQAGVDIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSDSIKAF
GTEVISQLCERLIEGGAPGLHFYTLNQAEPTVAVLRNLRG
>A0A3D5W9C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSSLSKALQSSDFVVTSELTPPKGLDLAPLLDKATLLKPHVSAINLTESHAARMAMDPVA
VGHLMLDHGVEPIVQMTSRDKNRLAIQASILGASALGISNLVFMGGDPPENGDHPDAKPV
FDLFASQLLGAVRALNSGTDLNGNALNKSTEIFAGAVVNPGASDPGAEIENLHRKIDGGA
EFFQTQAVYDVSAFSAFLDKARSSKPILAGIIPIKSVKMAQYMNERIPGVDIPDHLIEKI
AAAGDDKEAIAKISIGIAASTIRELRSVTRGGHVMAIGWEQYIPQILEQSQT
>A0A1M3JBX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium 68-20|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A2E7XGR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSKLYEKLSKGEFVVTTELTPPKGIDITDLLNKAESLKDCVDAFNLTDSHSSIMSLSPVA
VATRLLDLGCEPILQMTTRDRNRLGLQSDMLGAALLGIENLVCMGGDPPHLGDHPDAKPV
FDLATTELIRAAHSLTEGHDLMGNPLQGKPGFNIGAVVNPGVDDLDTEISRLQEKAEAGA
WFFQTQAIYXPFTFLQFMDHIAHLPIRILAGIMPIKSVKMANFVNNKIPGINIPEDLIRE
IEQAKNVRTTSTEIAVRTINEIREKCAGVHIMAMGNEDQIPKILAQTTQPG
>A0A2E1Z7Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MELNPKPIFSIELYPPRTTPDESKLDEVHDQLASLEPDFFSVTYGAGGSTKQGTKNIILK
YQQLGSNMVPHLSLGGTDRDDIRILLTAYKAAGINHLVALRGDLPPNTTTPVQHQYASEL
VEFIRLETGNHFHIDVACYPEPHPDSTSYKSDITYFKKKIDAGANSAITQYFYNADAYFY
FVDYCSKAGISVPIVPGIMPINNYTNLKRFSAKCGAEIPHWLQKRLEGFEGDVEGLKEFG
IEVVTTLCERLLAGGAPGLHFYSMNLAKSVNQIWKNLALSDRS
>A0A432I4E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTSFEFFPPRTEKGQKTLAQVRQELSAIQPEYFSVTFGAGGTTQEATLETVLDIQKNDS
IPAAPHLSCIGSKKDEVIALLDQYKKANINRIVTLRGDVPSGMRDIGDFHYANELVEFIK
TQYNDHFHIEVAAYPEMHPQAKNIQADLQHFANKVSAGADAAITQYFYNADAYFRFVDEA
EKLGVDIPITPGIMPITNHTQLVRFSNMCGAEIPKWILERLRCYENDLEALSAFGTEVVT
DLCQTLKNQGVDSFHFYSMNRTQPSLDIAKTL
>A0A1M3JWF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium 68-20|TrEMBL
MSLPISFEFFPPKTPEGAEKLRAVRQQLYALRPQFCSVTYGAGGSTQEGTFATVRAILAE
GADAASHFSCIGATRASVRAQLAELKAMGVKRLVALRGDLPSGYGMGGEFQYASDLVAFI
RAETGRDFHIEVAAYPEVHPQARSPEADLQAFAAKVRAGADSAITQYFFNADAYSRFVED
ARRLGLDVPVVPGIMPIMGSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIRAFGMDVV
AQLCEQLRRAGAPGLHFYTMNQSAATQALCQRLGLIG
>A0A523M714|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSTENNNVQVSFEFFPPNTEKMNRTLWDSIERLAVLEPRFVSVTYGADGSTRERTHAAVE
RIASQTSLTAAPHLTCIGADRAEIDDIAREYWDMGIRHLVALRGDPPTDTTDYRPHPNGY
PYAVDLVAGLRKVADFDISVAAYPEVHPEASNAIADLDNLCRKLDAGATRAITQFFFDID
KFLRFRDLCAAAGIESSIVPGILPITRFPQLRRFAEQCGASVPAWLSERFDGLEDDAQTR
QMIAASIAIEQVQKLQAEGISEFHFYTLNRSELTFAICHALGVRSNQAAA
>A0A1Y4HHJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerofilum sp. An201|TrEMBL
MFISRLYQQKDCVFSLEVFPPKQAASLEKLYGSLAQMAQLHPDFISVTYGAGGSAQGATC
EIAGHIQNQLGIPALAHLTCVGATPAGIGAVLDRLHGAGVHNVLALRGDANPDLPFSTDY
PHASHLADAITRRGGFCVAGACYPEGHPEAPTLAADVENLKYKVDAGADVLVTQLFFDNV
HYYRFLNLARKKGITVPVSAGVMPIVNRRQIERTVALSSASLPHAFTRMISRWQNDEQGL
FEAGIEYAVGQLRDLIESGADGVHLYAMNNPTVAARVYEGIRDLL
>A0A523MMF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MRRSQYLQQLQNLYTGTILKTFRESLRGSEFALTAELNLTPGVNVHQVLDQARVLGHSVD
AIQVPDHPHARPHMSGLAVAGLLAQHEYDPVLHLNCRDRNRIALQSDLLGAQALGIGNLL
LMRGRDLPADHRPPATGVFDLGAIDLVRTAATIRDGKALAGGQLPERPEFFIGTIATAFD
PKSGWEPEKLTVKADAGAQFIQLQLCLDMDVLRRYMENLVRARLLHSFYVLVSVAPLASA
ESARRVRQNMSDSLFPKGLVRRLEQAADAEREGVAICAQILREVADIPGIAGANLLNLGD
PALIVGAIEESGLRRNREAMR
>A0A2A4MUT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MLADKIKNKESGIVLYGITPPKKGTSLEKIEEIATRQMDRLQGLNIDGLILYDIQDEKSR
TSQERPFPFIETLDSFSYSRDYLSDLAVPKVIYRSVGKYSEAELSKFIEDAAVQKDLTVF
VGAASKSQEVTLSMKGAYDLKQQVDQALLLGGVTIPERHQAKGDEHIRVFNKIAQGCSFF
VSQGVYDVNASKNFLSDYYHYGREHNIPLVPILFTLTPCGSVKTMEFMKWLGISIPRWLE
NELKHTSDILQKSVDISEQNWLELKDFADENGIPIGCNIESVAIRKVEVDASIELLQRIQ
RAI
>A0A5Q4F1C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNSPVPASPVRDIRVSFEFFPPKSEKMEQTLWRSVERLQGLQPDFVSVTYGADGSTRDRT
HRIVSQMLAEKHLVTAPHLTCVGASREDIREIAQGYWDEGVRHIVALRGDPPQDSTGYVP
HPGGYPYAVDLVRGLREVADFEISVAAYPEVHPAAPSAEFDLDYLKQKLDAGAARAITQF
FFETDVYLRFRDRAAARGITAPIVPGILPITNFPQLTRFAGACGASVPAWLAARFDGLED
DAETRQMIAASTAIEQVEALRREGVSEFHFYTLNRAELTYAICHALGLRQQQAA
>A0A2D6VBD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTPVSFEXFPPRXTAGREKLTTGTATKLAALGPEYFSVTYGAGGSTKEGTKQTVTDLMDR
GWNAVPHLSVGGTDQQGTLDLVAYYKELGVKKILCLRGDQAESDAHNPQYAEDLVRLIRQ
HFGDRFEIVVGAYPEVHPDSASSHDDLTFFKRKVEAGADVAITQYFYNVEAYGYFVDQCQ
SLGIDIPIVPGVMPITNYASLCRFSEKAGADIPRWLDRAMAQRQDSDEELGKFGVEVVTR
LCERLIELGAPAIHFYTLNRWGATTKVCANLGLNVS
>A0A2G6EH12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MATIRNCLAELCMKQQVIDLMSDFTIETTPGSAAKIPDYREHLRPGCVVAVTFLPGSDYN
DTIATVKRLRDEGFVPVPHIVARSIPSERDLTNFLDAVTGESGVDHVVALAGAVDKPLGP
YDSSMALLETGQFDRVGIRRIGVAGHPEGSPDISDELLQQAIDFKNDFANRSDADLYLVT
QFVFEAEPVIAWDKAIRASGNTLPIHVGIPGLASLKALIGHARACGIGASMSFLTRQARN
VARLLKVQSPDKLIIDLARYKAENADAGIHKVHLYPLGGLRRTAGYGYALVDGKFDIGRH
GTGFRLHEKIE
>A0A6L5QY66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces kandeliae|TrEMBL
MTGTEPDGVAARPRVPISFELFPPRTDAAAIALGRTIDRLAEVDPAFISVTFGAGGSSRD
RSLTVLRYMLEHTSVEPMAHLTCVGSSHAEANRLVREFLDAGITSFLALRGDPPAGAADA
EDAIGDLHSAAELVQLIHRVQEEREPFGQSRIPGMPGVTAIRDRPRPERVAVAAFPSGHP
RSRGSNQDVDVLLAKEVAGANLAITQLFWHADDYLAFVQRARAGGVTIPILPGIMPVTTL
SRLARLEQLTGVPAPAGLAIDLEIEPDADAQFELGVAYAADLAAVVLAGGAPGLHLYTFN
RHEAVLAVLDRLGLATAHAHAGTERNTRER
>A0A8B8JA63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phoenix dactylifera|TrEMBL
MKVIEKIRAAEGEGRTVFSFEYFPPKTEEGVENLFDRMDRMVAHNPSFCDITWGAGGSTA
DLTLDIANRMQNMICVETMMHLTCTNMPVEKIDHALDTIKTNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVQHIRSKYGEYFGITVAGYPEAHPDMIQGEGGATLEAYSNDLAYLK
RKVDAGADIIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTR
IPPEITAALEPIKENEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMNL
GLIEESKISRSLPWRRPTNVFRAKEDVRPIFWANRPKSYIARTLGWDQYPHGRWGDSHNP
SYGALTDYQFMRPRARDKKLQEEWAIPLKSLNDIKERFMNFCLGKLRSSPWSELDGLQPE
TKIIDEHLGEIILKGFLTINSQPAINGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKDKIN
LLIEKCKGFPSLTYIAVNREGECLSNVAPNAVNAVTWGVFPAKEIVQPTVVDPASFMVWK
DEAFEIWTKGWACLFPHGDPSRELLEQVQSNYFLVSLVDNDYVHGDLFAAFKDI
>A0A7W8FS30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus koreensis|TrEMBL
MKLLDALKTRVLTGDGAMGTLLYSYGIEYCNEELNLQRPEIVSKIHQDYIKAGADIIQTN
TYGANAHKLARYGLEEQVKDINLAAIDIAKRAAAPGGQYVFGTIGGIRGMRKSDATMQEI
IAMVDQQAQHLLSGDPDGLLLETYYDFEELAATVTHLKSMTDTPLIAQVSMHEPGILQNG
MSLNDALHQLEALGADIVGVNCRLGPHHTIQAFEEVSLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGRAALLLREEGVRLIGGCCGTTPKHIEEVKKRMRNLAPVTEKKVVARKPIV
IREAEALDVKPLHEKAKTERTIIVELDTPRHLDVSKFIEGSKALNTAGVDAVTMADNSLA
SPRISNMAMGSILKLQENIRPLAHITCRDRNLIGLQSHLMGLDALGMHDILAVTGDPTKV
GDFPGATSVYDVSSLELIQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVVSRAVKR
LEQKIDSGADYFISQPVFTKEKIIEIYEETKHLSTPIFLGIMPLTSIRSSEFLHNEVPGI
KLSEDALERMRACGDDKDRATAEGIAIAKELIDTAAGLFNGIYLITPFFRYEMSVELIDY
IRQLDLQKEGESSHVQNTY
>A0A2T6DMC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium LW23|TrEMBL
MANVLDLLDDRVLLGDGATGTYLFSLGVPATQCLEETNLTNRDLVARVYSDYAQAGANIV
ETNSFGANRIRLARYGLEDRVNEINWLAARIARDAFKAHGDVFVGGSVGPLSLRPTDPVL
TQDDIRAVFREQIGALLDGGCDMIFLETFSDLAELMLALDAFQNLSNVPVVTSLAVTEEG
RLGSGEDLATAWQKLRAAGADIISLNGTLGIQATRGVLSDLDVTPDDYIAVYPNAGRPEF
YEGRFNYNASADYFARSVPDLVAQGARLIGGDYGTTPVHIAAMAPVIRELKPVKSKKVLR
SKDIRVTANPAPSALTPGAREIVDYPKEPNLIEAMKGDKPVQIVELDSPKTLAMGKFLEG
ARALKEAGAAAITLADNSLAILRVSNFAAAVMLRDSVGITPMIHLACRDRNLLGMQSELM
GMHLLGFQHVLALTGDPSKQGDHPGATSVYDLNSVSLIKLIRGLNGGMSAAGRKLNGNTE
FHIGCAFNPNARNLESQVKKLEMKMAAGAQYVLTQPVFDPALVHETARVLKPLGIPVFIG
VMPVLHSRNAEFLHNEVPGIKIPEPIRERLRAVDEKAGAAIGLELAREIKAAILEHYNGV
YVITPFLRYELSVELLGS
>A0A839GMP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rufibacter quisquiliarum|TrEMBL
MKVTEHLQNATQTLFSFEILPPVKGTSIQSIYQGIDPLMEFKPPFINVTYHREEYVFKER
ENGLLEKITIRKRPGTVGICSAIMNKYHVDAVPHIICGGFSKEETENALMDLNFLGIDNV
LLLRGDAVKTEPGFRPHKDGHAHASELIQQVVQLNHGKYLDEEMENPVPTDFCIGVAGYP
EKHMEAPNLSTDLKYLKQKVDLGADYIITQMFFDNEKFCDFVKACRAAGINVPIIPGLKP
LTTKNQLNVLPRYFNIDLPEDLVNAVEAATTPAQVKQIGIEWTIQQCKELVEFGVPCLHF
YTMSKSEATAAVARAIF
>A0A4W2D8W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos indicus x Bos taurus|TrEMBL
MDCPKPKVFPVGHCCPSLGMRASEAGSGRLSVPPSISRNSAMVNEPRGNGSPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCPVLPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>A0A6N1EEA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. W8901|TrEMBL
MTFDAVRGRNSAGWETQTPSIVDRISSSEASKSGRIPFSVEFSPPRDADAEARLWRAVRE
FERLGPAFVSMTYGAGGSTRDRTVRVTGRLAEDTTLLPVAHLTAVGHSIDELRAMCGAYA
DRGISNILVLRGDPPGDPLGEWVKHPDGVEYAEELVRLVRDMGDFHVGVASFPEGHYRAP
DLEYDTKYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVVAYDPEQGEKPIIPEIMPITSL
RSARRSLELSGSKLPAALEERLTRAAGDGPEENRAAVREIGIEVATEMSERLIAEGAPCL
HFITLNFARATGEVLANLGMSASTSV
>A0A318DT27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella sp. AtDHG13|TrEMBL
MSSISFEFFPPKTDEQRDQLDQAARLLKSHAPEYVSVTFGAGGSTLSYTGETVHRLHTAH
GLNVAPHLSCVGGTRAELKALLDDYRAAGYRRIVALRGDLPSGMATPGDFRYASELVRFI
REHSGDHFHIEVAAYPETHPQADDALADLRHFKAKVDAGADGAITQYFYNADAYFRFVDD
VQRLGVKVPIVPGIMPISNFSQLKRFSDACGAEIPRWIAKRMQAHGDDAASIRELAADVV
AQLCRRLLEGGAPGLHFYTLNRARATRAILDRLHG
>E2SAK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium marinum DSM 15272|TrEMBL
MPHDDRSLLEQLRDQRPTVSFEFFPPKDDDGEQLLWTTIAELEPYDPTFVSVTYGAGGSS
RERTVRITARIAEQTSMRPVGHLTLVRQSREEIAEVLQQYADAGVSHVLALRGDPPGGPR
ADWEPHPGGMDYAIELVELAHEIGGFSVGVAAFPEGHPDAPDLDEDARVLALKAGAGAEF
AITQLFFRASDYFELVDRVRAQGSDIPIVPGIMPILNFAQVARMAELSGAAMPAEVLAQI
EPIADDKPAVRARGIALATQLCRDLIAGGAPGLHFMTLNRSSATREIFEALRGEGLV
>A0A508A6H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter aestuarii|TrEMBL
MSTSHRTPVSFEFYPPKNDEQRAQLDRTTEKLRRLAPEYVSCTFGAGGSTLSYTPETVSR
LSGKHGLDAAPHVSCVGGSRAELSELLGRYRQMGCRRIVALRGDLPSGMGHPGDFRYASD
LVAFIREEHGDHFHVEVAAYPETHPQARDAHADLAHFKRKVEAGADGAITQYFYNADAYF
RFVDDARAHGVDIPIVPGVMPISNFSQIRRFSEMCGAEIPRWIVQRMQAYGDDAASVRAF
GADVVAGLCQRLVAGGAPALHFYTLNLAKPSLSVIERLS
>C5T5U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax delafieldii 2AN|TrEMBL
MNAAHAQGTGFPVSFEFFPPKTPEGADKLRVARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILSEGVGAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFHY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPEADLQAYVTKVRAGADSAITQYFYNSD
AYFRFVEDARQLGADVPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>S9VSH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691)|TrEMBL
MKISDKLQHPNWKDRITWSYEFFPPKTSTGIQNLYSRIDRMKKWGHPMFIDVTWGAGGST
SDLTPVIVNVAQKEFQLDTCMHLTCTNMSEEMIETALKKAYETGCRNILALRGDPPKNET
EWTQVEGGFRYASDLVRYIKKNYGDEICIGVAGYPEGYSPDDDLERSLKHLKEKVDAGAS
FIVTQMFYDADNFVEWVKKVRKMGITVPIFPGIMPIQAWDSFIRRAKWSGVKIPQHFMDT
LLPVKDNDDDVRERGTDLMIQFCRTLIENGITRLHFYTMNLEKAVKMIIERLGLLDEEVK
DVTEKSENQLTTNRTEIFPDGTKRANEDVRPIFWRTRLESYISRTDQWDEFPHGRWGDSR
SPAFGEFDPSRHGLRQSTGEILSLWGSPKSYKELGELFADYCMKKQSSLPWSDVPISDEA
KMIQSQLVNINKRAYLTINSQPALNGVKSSDPVHGWGPTNGYVYQKPYVEFFVHPSLIEE
LKSSLHQMGDTSYFFITVDGKLDTNAAYEVPNAVTWGVFPNREVIQPTIVESTSFLAWKD
EAYFLGMAWASAHDPNSATHKLLVSMMSSWMLCVIVDNNFERGQSLFDVFSKIKSLEDIH
PELYNGVAI
>A0A4R4NPD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea longispora|TrEMBL
MPFRGTEDAVLAYVPRTIPVTVTTTEAKGLAATVDLARRLAGHGYSVAPHLAARQVRDGR
QLTDLVTELREAGIDGIFVIAGDVARPAGGFPDALSLLEALDANGHHFRRIGIGGYPEGH
GSIRQELIDRAIELKARYATHVITQLCFDAATISAWARRLKERGVGLPIHVGLPGAVSRQ
KLIRISAGLGLGQSARFLNKQQSLLWRFFLPGGYSPDRLVERLAPRVCDPEGNLAGFHLF
TFNELEKTESWRRGMLLRAGYLT
>B0CFE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acaryochloris marina (strain MBIC 11017)|TrEMBL
MTSPIAPVHDLSEQLSSPIAHRFQAAIHAGEFLVTAEVMPPKGGSIQHMLDQALHLKDWV
HAVNITDGSRAVLRMSSLAVAAILRQQGIEPICQMACRDRNRIALQADLMGAHALGIHNI
LALTGDPIKAGDFPKAKGVFDLESIRLLNIIRQLNNGLDGNEKPLPDGPTHLLVGAAVDP
QLASWSGLQSRFEKKVMAGAEFFQSQLIVDFDRLEKFMTEIATPAKKPILAGIFLLKSAK
NAQFINRCVPGVNIPDAIINRLDKATDPLQEGIAIASEQVQQARQLCQGVHMMAVRREDL
IPQILEQAGVTPVRQTQTIS
>A0A2T0VQZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas ventosae|TrEMBL
MSTQEHPLGISFEFFPPSTDAGREKLVGVRDALASRAPRFFSVTYGAGGSTQDRTLNTVR
MVRESGFTTAPHLSCIGSDKGALRELLARYREEGIDSLVALRGDMPSGMGGGGIGQLRYA
NELVEFIREETGDHFEIAVAAYPESHPQAANLEQDLANFARKMKAGADIAITQYFFSAES
YFHFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIG
AFGEEVVSRLCQRLLDGGAPGLHFYTLNQATPCLRILDNITG
>A0A2J8KXC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pan troglodytes|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLH
>A0A7K2WC43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID2888|TrEMBL
MGTSLLDDFSLEMTAKDISGLEEAHPTIPPGTRINITFLGNEDLPMRLAAARAVKRLGFV
PVPHISARRLKSRAELEQFLAGLKADGTAENVFVVGGDPARAEGPYEDALAVIRTGLLRH
HGVRHAGISGYPEGHPAITGPVLWSALTDKHAALGEELLAGDVITQFGFDVDPVLAWVEE
TRARGMDLPIRIGVPGPAGVRRLMTYAARFGVGTSAAIARKYGFSLTNLMGTAGPDRFLR
ALAEGYDAGRHGVVKVHFYTFGGLGATSEWIARFRQEG
>W4S4S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. pruni str. MAFF 311562|TrEMBL
MIDPDTPSLASTITEAYSLEVSAKHIAGLAAAAPRIMRGATIAIPYLPNQDDDARLAAAR
MVRTLGFQPMPHLSARRIASREQLHAFVSRAVDDAGVERCLVIAGDPPAPLGPFPDSLSL
LDTGVFERSGIRTIAVAGHPEGHPSMPAADRWEVLQRKCRSIAERGMAPLIVTQFAFDAD
IVLRWLQALRAHGIAYPVRVGVPGPAGVAVLARYAASCGVSACASMLSKYGISLGKLLGT
AGPDRFVERLATGLTDAHGEVRMHFYPFGGIAQTVAWVEQYRSRSAHV
>A0A501PEB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus symci|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A416UZC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF17-2|TrEMBL
MKIRDIIGQEKATLSFEVFPPKKDTDFASVEAAALGIAALRPSYMSVTYGAGGSTKGHTI
KLANEIQEKYGVPTIAHLTCVCANKDSIRTALSEMKNAGIENILALRGDIPKNYDGQVFT
DFAHASELVKLIKESGDFCVGGACYPEVHPDSANKQDDIANLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRIREAGIAVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEVAAGIQANLSDILLV
>A0A2S0VWC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharobesus litoralis|TrEMBL
MKVSFEVVPRTEDATREQLEFVQQHLPQVNTINVPDLLRLPIRSWEGANFIDRNQYDFIP
HVRAIDFNRPEKRLQKLIHAYQLDKVLIVSGDPPPDMSHRVYDTKVLDLIADIRADFPDI
KIYCGFDPYRSSVKQEKEYIQQKFDVGCDYILSQPFFDMRLLEVYSDFLPPEKTFWGISP
VVTEKSQAYWERMNHVVFPSSFDASYEWNIDFTQQVIEHSAKVGSHIYFMPIRIDLERYF
KPVAAALAKI
>Q8E2W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus agalactiae serotype III (strain NEM316)|TrEMBL
MSKFLEKLKTDILVADGAMGTLLYTYGLDTCHESYNVTHPEKVLAIHQAYIEAGADVIQT
NTYGAQRHRLKNYGLEDQVVSINQAAVNIAHQATLGKETFILGTVGGFRSQRQCDLTLDN
IVEETLEQVEALLATGQLDGLLFETYYDIEEITTVLKIVREMTDLPIITNISLHEAGVTS
NGKPIVEALSQLVMLGADVIGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASQLSLDGE
NSQYQFSQNSEYFGKSAELLVAEGVRLIGGCCGTTPDHIRAVKRSIRGLKPIERKVVTPI
IPVKDFVRRIRRTDTLVDKVKKEVTIIAELDPPKHLDIVQFQKAIRAIDQKGIAAITLAD
NSLSNTRICNLSIASLLKDEISTPFLLHIACRDHNLIGLQSRLLGMELLGFNHILAITGD
PTKLGDFPGATSVYDVTSFKLLSLIKQLNQGLSYSGASLRRPTDFTVAAAFNPNVKNLTR
TVKLIEKKVASGADYFMTQPIFDHSVLKELADLTKTVEQPFFIGIMPITSYNNAVFLHNE
VPGIKLSESFLSALEKVKDDKEACLTLALNESKSLIDEALNYFNGIYLITPFLRYDLTLE
LIDYIQKKQVRKSS
>A0A538SR18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium|TrEMBL
MPSPFLDRLARGPLLADGAMGTVLYQKGVGFGESFDALNLTKATQVESVHRDYLAAGAEL
IETNTFGANAVRLAPHGLEEKVRAIARQGVKIARTAREIVGVDAFVAGAIGPLGKPLEPF
GQISAAEAEGIFRATAEGLLEGGCDCFILETFQDLNEILAALRAVRRVSLGIPIIAQMTF
GDDGKTLYAHTPSLVVRALKQAGADVVGINCGVGPQPTLEVLEELIAAADGTPVSAMPNA
GLPQFVEGRFLYLASPDYFAEFAARAVALGVRIVGGCCGTTPAHIRAMRERLESHLPAEK
LAPGAEVRVLEPEPAVAAPPAEREEPSLLRKLREKFVVSVEIDPPRGINTRKVMEGARLM
AQANVDAVNIADSPLARIRMSAMALAYQIHTHFPRLEIILHYTTRDRNLMGLQSDLLGAH
ALGIRNILCLKGDPPSLGDYPDATAVFDTDAVGLMNICRRMNQGTDLAGNSIGAVTRFAF
GCGVNPTAENLDAEFEYVRRKLDAGPQFVMTQPVYDVECWKRFVDRLSGLARIPILIGIL
PLQSFRHAEFLHNEVPGIHVPDWVRARMHEAGNEGQAAGVELARDLLARCKSMANGVYLM
PSFGRYENCLEVLEGAR
>I9NU82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelosinus fermentans JBW45|TrEMBL
MKLSDRFNKGKALVSFEIFPPKQTVTLESIFKTTEGLQTLNPDFTSITYGAGGSASDRTI
ETADKIKNTYGVEALAHLTCINSHKDDIDLMLNQLQAHNIENILAMRGDYPINKNNNKGK
ENTYQYAKDLIAHIKSNHDFCIAAAAYPEGHPECPDLNTDLLHLKEKVNSGTDFLITQMF
FDNTILYDFLDRIKQVNITIPVSAGIMPLLNSKQVGRIKGLCGASIPKPLQNIIQKYENS
PLDFEKAGIEYACSQITDLIANQVDGIHLYTMNKLEQSKSIIQQTNLR
>A0A0A0AQT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Charadrius vociferus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVHGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>R4TCD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis keratiniphila|TrEMBL
MDLVRRIDRAAGEFLLFALTPPRLATAHERVQQIADATMARLRPLDLDGLILYDIDDEAA
RNPARRPFPFVPTLDPANYLADNFTSWQTPVIVYRAVGKYAPSELRTWLAAQDPARVMTV
LVGASSSKIDTMTSLADAQALRRDANPGLSLGGVAIPERHSRRDDEHHRLLAKQDAGCRF
FVTQVVYDVNAAKNLVSDYHYECVARGRAPVPIVFTFSVCGSLKTLDFLRWLGVDVPRWI
ENDLKHAADTLEASYQLALAAATELMTYCRGLDVPFGINVESVSIRREEIEASVRLAERL
RAEIKG
>A0A3S3UUN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M4B.F.Ca.ET.089.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVVREFADMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKSAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A2P9I0M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura parvosata subsp. kistnae|TrEMBL
MKADGDPVISERPGDLLSDFSLEMTAKDAGALEKAAGLLPAGTRVNVTFLAGEDSALRVH
AARVIRRLGFRAVPHVSARRLTSERELMRHLSALADAGAAEEVCVVGGDPARPAGPYEDA
PALIRTGLLARSGVRQVSVAGYPEGHPHIPPAELWRALEDKHRALLEQDLGMTVITQFGF
DAAPIVRWLGELRARGIRSPVRVGVPGPVGVKRLLRYARRFGVNSSAGIVRKYGISLTNL
LATAGPERFVERLRGQLDPARHGDVRLHLYTFGDLPASARWAHEHRSARTP
>A0A2M7L2C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium CG_4_8_14_3_um_filter_66_20|TrEMBL
MAKEKTALHKQLESGKQVLLTLASPPKGSDPAPLRELAQQFAGKVHAIGVSDNHHGVTMS
ALAAAALIAAEGVEPVLTLTTRDRNRIALLSDCLGAQALGVRNFLCTSGTHQTLGAYSAA
KSVFDLDSVQLTQVLTNLCANGAGEERLAGEELCLGGVAAPYADPLEMQVARLAKKVETG
ARFLVTQPVYDLARFEQWWTAVTERGLQDRVAILAGVEPLADADAAQAEARRRPSPVIPA
AVLERLAAGADSRAQRELGIDLAVETIDRLSKIDGLRGFTIGGEPTAALAVIERSGLVID
>A0A1V5KJQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium ADurb.Bin474|TrEMBL
MNIARILASQQTCFSFEFFPPRTEEASQALFESIGRLCPLNPGFVSVTYGAGGGTRQLTH
DLVVRLKKETGLTIVPHLTTVGHTRAEVSAILDRYTENGVGNLMALRGDPPKGMSSLPSI
ADGFAHAGDLVAFVRSRYAGMGIGVAGFPEGHPECPNRMLEIDYLKAKVDAGADYICTQL
FFDNRDFYDFCERCELAGIRVPILAGIMPITSLKGMKRMAELALGARFPARLMRALSRAT
SEEGVQEIGLHWATEQVSDLLDHKVRGVHFYTLNRSDTTLRIYKSLGLGLEDGKPA
>A0A3G8VEA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plantibacter sp. PA-3-X8|TrEMBL
MTTTEPACPRRTPFSFGLYPPKTLDGGVALARTVEHLAAAGPEFISVTFGAGGSSRTASL
DVLRSIRTSTSVDPMAHLTCVGSTHAQASRLIKDFLDAGVHSFLALRGDPPAGAVEGDAF
LGDLGSAAELVQLIGRVSAEHEPYAEGSLTGLPGAVQLGRRRRPRIAVAAFPNGHPRSRS
TTQDLDTLLAKQAAGATLAITQLFFHADDYLAFAERARRHGVTMPILPGVMPITSPARLR
RVLELSGEALPSDLAIALEVEPDEAGRIDIGTEYSARLIRDVVAGGAPGVHLYAFNQHRT
VLDVLHRAGIPMQGDRPVRHPIPDPLTSKDAR
>A0A3B9CP60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp|TrEMBL
MKVKEILAASDRTLISFELLPPLKGGDIGKVYNAIEPLMEFSPSFINLTYHRDEEVIRQR
PDGTLERITVTKRPGTVALAAAIMKRYDVEVVPHLVCGGLDRHTIENILIDLNFLDIDNV
MALRGDPAPGERFFTPTRGGHAYCSDLVRQISDMNRGVYLDELQQNPIPTHFCIGVAGYP
EKHYESPNLSQDIRNLKRKVDAGADYIVTQLFFDNARFFDFVERCRAEGITVPIIPGLKP
VSSLKHLEMLPRTFHIDMPEALTEELSRCRTDEQAKEVGIEWSVGQAKELKAAGVPAIHF
YTMSRSGNICEILKRVF
>A0A6D2HN08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microthlaspi erraticum|TrEMBL
MKVVDKIKSVIKEGKTAFSFEFFPPKTEEGVENLFERIDRLVSYGPTFCDITWGAGGTTA
DLTLEIASEMQNVICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQEK
FVQVEGGFDCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFLNDCRQIGINCPIVPGIMPISNYKGLAYGWFLQNQE
MCKKILAHGITTLHLYTLNVDKSATAILMNLGLIDESKVYRSLPWRRPANVFRTKEDVRP
IFWANRPKSYISRTKAWNDFPQERWGDSRSASYGTLSDYQFMRKRSRDKKLQQEWVVPLK
SIQDVQEKFKELCLGSLKSSPWSELNGLQPETKIINEQLGKINSSGFLTINSQPSVNAAK
SDSPAIGWGGPGGYVYQKAYLEFFCSMDKLDTLVEKS
>A0A7Y5N5W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dermatophilaceae bacterium|TrEMBL
QRLLDEGAPGIHFLTLNRSSATLEVFGNL
>A0A7W7DTB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces luteogriseus|TrEMBL
MALGTASIRSDHARTVRDMLADGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWDADVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLERIGSLTNAAF
PPVLKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSPQA
>A0A6B9ZH92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga agri|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSMDSIYDHLDPLMEFKPAFVNVTYHRSEHMFKKR
ADGTFEKVEIRKRPGTVAICAALMNHYDVDAVPHLICGGFSREETENALIDLNYLGVDNV
LVLRGDAPKNETFFEPEPHGHRYADELLRQVVHMNNGIYLEEDLQGGVKTKFCIGVAGYP
EKHFEAPNMQTDMNYLKRKVENGADYIVTQMFFDNQKFFDFVSKCREAGITVPIIPGLKP
ITTRKQLTILPRTFHVDIPQELANEVLKCKTDKEVEEVGTEWLIRQSKELKTFGVPVLHY
YTLGKPHVIRKAVAEIV
>A0A855M0P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae complex sp. ECNIH14|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A431NBG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MTVRDLLATSVLVGDGAMGTMLHAAGNSLDQALPALTLTEPGLVRTIHDSYVGAGVDLVQ
TNTFGASRLRLAEYGAADDVARINAEAARLALEAAARADRPVFVAGSVAPAVSVHQRRRV
GADERRAAVREQVEVLVGAGVDVVMLETFGHLDELVEASEVALEVARRTGDVPVVAQATF
GTDHHTLSGHTPHELVAALSGLPLAAIGVNCTLGPQGCLAVLRELRSHTGRPLTVQPNAG
LPRRVAPARFEYDIDADYFVRYTRQLLDAGAALVGGCCGTTPGQLAAAAAAVAEYRAQQP
VTVVETSPSLPVQVSRPGLFDAAGPLVGVELPPPTTGGVDETVSLAADLREAGVGLVCVP
ATSGPRAQVNSVDLALHLHDRLGVTTLASVTTWDRTIMALQADLLGAHALGVRGVLCETG
TPPLVGDYPHVDGIWDVDSLGLIELLAGLNEGTDYHGLRLGTKTSFDIGARVNPGSRDPG
RAAAGALDKIAAGAQFLITRPVYEPTGLERVVEAVDGRVPILVAIRPLTGFDEADYLAHE
VPDVTIPDGTLAALADAGPDAAAAGVDLALALAEQVRPMTRGIVVTGDSDVAATVRRLTT
L
>A0A0J6ZG55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium chlorophenolicum|TrEMBL
MTTIDGSDTTIGHLVATANIEVIPLRGAEEKTAAIPTSTTVTITCSPKFGLDRTLDHVVR
ARESGHRVVPHLAARMVEDEAQLKRFLATLSSAGVDDLYVIGGDGEEPVGKYSEAFDILE
AIQGLDHNLQRIGVGCYPEGHPNIPDAALLDALQRKQPYADYMVSQLCFDADAFTGWLRT
MREAGITLPVRIGIAAPLQTRKLIELSLKIGVGSSVKFLTKQHGFVGNLLLGRSYTPETL
ITEIVAESDFEQLGVEGLHMFSFNQVDATVEWQSRMSAAIAK
>W1IN63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus cabanillasii JM26|TrEMBL
MSFFHANHQEALNQNLAELEGQIRVSFEFFPPRTTEMEQTLWKSIDRLSKLKPNFVSVTY
GANSGERNRTHSIIKGIKDKTGLDAAPHLTCIDASREELRDIARDYWKNGIRHIVALRGD
LPDGSCKPEMYCTDLVELLKNEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFAAITNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A2E5SA06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillales bacterium|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRDRLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHRQGISTAPHLSCVGGTRQDIAELLDLYREHGITRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEDDLKNFARKVKAGANSAITQYFYNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSESIRK
FGEEVVTDMCERLLKAGAPGLHFYTLNQAEPSLTIWNNLGISDREKIAF
>H2BVT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gillisia limnaea (strain DSM 15749 / LMG 21470 / R-8282)|TrEMBL
MKITEHIQASNGKALFSFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYVYTE
QKNGFLEKKVVRKRPGTVGICAAIQNKYQVDAVPHILCGGFNKEDTENFLIDLDFLGIKN
VVALRGDAVKSETYFSPEPGGNIYAKDLVEQINALNQGKYLDHAMENGNKTDFCIGVAGY
PEKHMEAPNLDKDIERLKEKVKSGAEYIVTQMFFDNSKYFEFVEKCRKSGINVPIIPGLK
PIATKNQLTVLPHRFHVDIPDDLILEIEKCRDNKEVHKVGIEWCINQSKELIEKGVPVLH
YYSMGRSTNIQKIASAIF
>A0A2X3U7Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus thermophilus|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILLALDDMKGSAPHFISVTASNNKYSIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRELDAVGVNRILALRGDIIPGVEPLKDFRYATD
LIEFIKAEAPNFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETARHIYEATHSLFKHHSQVGAL
>A0A292QLI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Gastranaerophilales bacterium HUM_1|TrEMBL
MELKEIYDGKTFVETGLAIHVPKISFDVFHPTSGDISKLFEELRVLKKYNPSLVSLTYGA
SGSGARFSKEDMKTILGLELNLMPHFTCVCETKNAIERNIINIENLGIENILALRGDIPQ
GVNPCSLDFEHANDLVEFVHEKTTLSIGVVGYPEGHVESPSLDVDIENLKRKVDAGASAI
FTQLFFDNDKFYRYVEKVEKAGINLPIIAGIMPIRSSAQIQKMLEMTHVDIPQNLINELE
RFPQQAKKIGAEFAIHQCHNLIDNGIQALHFFTLNHSDQVSEVLDNIL
>A0A149UF88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter oxydans|TrEMBL
MKRLLSGKLADHPSLCHSDMPVPVLSFEVVPPRTDAMEQRLWQCIRRLAPLSPRFVSVTY
GAGGTMQARTQATVLRLKQETTLVPAAHLTCIGATREEIDDIARTYWQAGVRHLVALQGD
APAGTDYTPHPGGYAYASDLVAGLRRIADFEISVAAYPETHPTALSSQADIDNLKRKFDA
GASRAITQYFFEASTCLRFLDRCLAAGITAPIVPGIMPVSNYDQIARFSALCGVTVPAWL
THLFEGTAKNPELCRIAACIVAAEQVRTLQSHGINEFHFSTLNRPDLTCAIAHLLGVRPA
SETDS
>A0A2E2WQY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Legionellales bacterium|TrEMBL
MESQKKYKPQFSFECYSPKTPEAVTYLQNXQLEXAQLNPDFFSVTYGAGGXTRNMTFETV
LDIRDKTGVESVPHISCVGNWGXDIKNMLQNYIDNDIKRIVVLRGDLPSGTVGYGQFQHA
NELVEFIRKQTGDHFHIEVAAYPEFHPQAKSAXADIDNFKRKXDAGANGAITQYFFNPFS
YYRFVEHCEKLGIDIPIVAGVMPITNCTQLVRFSEGCGAEIPRWILKQLQGFGDDRESIF
KFGVDVVTELCDQLLSNGVPGLHFFTMNKSAASNLIWKNLGLDRRVIH
>A0A1H1YN68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas oryzae|TrEMBL
MSQERRYSFEFFPCKTEAGHEKLLNVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDTKAELRQLLTTYKDAGIQRIVALRGDLPSGMGLANGELRHANEL
VEFIRAETGEHFHIEVAAYPEVHPQARSFEDDLHNFVRKAQAGADSAITQYFFNADCYFY
FVERVRKLGVEIPVVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFG
EQVVTEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1X0N432|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas floridensis|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLTVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKADLRSLLSQYKEAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQSFG
EDVITEMCERLLQGGAPGLHFYTLNQADPSLAVWNNLKLPR
>A0A4R0IX56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sindirgiensis|TrEMBL
MANGLPSTLPGGAPTIRELLASGDRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWVAHPEGLDHAIELVELIRSLGDFCVGVAAFPDKHPEATSLEADAQVLAA
KARAGADYAITQMFFGADDYFRLVDRAAALGCDIPVLPGIMPVTNIKQIQRMADLTGMAL
PAAVTDRLHAVEDDPAAVREVGVEIATELCERLLAGGAPGIHFITLNRSTATRQVFRNLK
TPVVS
>A0A345IGN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus wulumuqiensis|TrEMBL
MTRISLELVPRSRSKLRAELALVAEQFPGVDTVNIPDLTRFSTRSWEGCAFAPAGLRAIP
HVRAIDLNPKEPLPMVGAFLAHGIEEVLIVSGDAPSDMNRRVYNVDAEQAIRRFRRELPH
VKVYAGLDPYRQSFAAERDYLERKLEAGASGFFTQPFFDMRLVEAYADIVPDGAEVWWGA
TTVTEEGSLNYWQTRNRAVFPRAFELTMDWDRRFAAQLLAFARAQGQHAYFMPVKTDVGA
YLQGIV
>A0A420XW27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Motilibacter peucedani|TrEMBL
MSKPPSHQREQLLFSITPPRRSSPPEDAQRIATVTVERLKQLDLDALIVYDIDDESDRNP
DERPFLYLPTQDHGDFHARHLTEWDRPVVIYRCVGKYDSTQLETWLAAQDPELVSTVFVG
ASSSSKQVLTSLAEAQAVWRNTCPELPLGSVAIPERHSGSGREHERMLRKQRRGASFFVT
QVVYDADAAKSMVSDYFYACHDQGQEPAPVIFTLSVCGSLKTLAFLQWLGVDVPAWMRND
LQRSEDPLSVSFEHCVATAAELAAYCRRLGAPFGFNVESVSIRRAEIDASVRLAERLRAG
>A0A5E5PPY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Gammaproteobacteria bacterium|TrEMBL
MKTSFEFFPPRTEKGKQTLHQVRQELSSINPEYFSVTFGALGTTQEATLETVLDIQKNDT
VAAAPHLSCIGSKKEIIIELLDQYKAANINQLVALRGDIPSGVRDIGDFHYANELVEFVK
SQYNNHFHIEVAAYPEVHPESKNRQTDLQHFADKVKAGADGAITQYFYDAEAYFKFVDEI
EKLGVSIPIIPGIMPITNYTQLVRFSNMCGAKIPNWILKKLELYQDDLDSLSTFGLEVVT
NLCQTLKEQGVNNFHFYSMNRSQPSLEIAKHL
>A0A1Q8X5I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MHDNEPTGPTAAAGSRGEALSSAETGTARRLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPAGGVTGGGGRGSEHEPEAGRCEAAPRVRAVQEQTNPSECVLAH
VLDSSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRAEDVAGELRH
ADDLVRVIREVEADFFGDGRRHVTIAVAAYPATNDHIEAIEVLAAKQAAGADMAITQVFY
DAADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPTGLRSSLGSASGAT
LVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDA
VDRGYLQATPGRGPSFLRRGFARAAVSSHHPVQPLTTITKENA
>A0A4W6CQS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lates calcarifer|TrEMBL
MVNQVQRGDGTCQSCKSDSSGASNSGGESSKESSRCSTPVLDSDRSDRLRDKMRRRMESG
DHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAT
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVISQLFFRADTF
LKFLDDCRQIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIQQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLKMWGEELMNEVSVFEVFTCYITAQPNRSGHKVMCLPWNDEPLASETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGRNLTNAPDLQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELEPPQRINKVLIYLL
EAFL
>A0A8H5Z1E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium mundagurra|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPTNEWDTLKAKITSPELQDSVCFYASNARGDYLSSDSSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A1N7BRU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. RU39B|TrEMBL
MGFHSARQVEALNQSIADLDGNISVSFEFFPPGSESMEQTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIQDRTGIIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGVDKPDMYAADLVALLKAEADFDISVAAYPEVHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLENDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKA
>A0A542E5K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lapillicoccus jejuensis|TrEMBL
MSVPTATTTAPTTAPTSAPTTRSIPQALAAPEPSISVEFFPPRTDEAEATLWDTVRRLEK
RHPSFVSVTYGAGGSTRDRTVRVTERIARETTLLPLAHLTCVGHSMTELRSVVGAFSAAG
ITNLLALRGDPPGGPGEEWVRHPEGLDHAEELVALTRSLGPFTVGVAAFPDRHPESPDLD
HDADVLVRKADAGAEFAITQFFFTVEAYLALRDRVAARGRDLPIVPGLMPVTSVRQLARM
TELSGQPVPRSVTDRLEAAGDDPEAVREVGVEITTELAQRLLAEGAPGLHLITMNRSPAT
LQVWENLGVTAAH
>A0A1J5T6N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MLIEKIRNRESGIILYGLVPPKKGTDPEKITEISTRQIQRLNGNHIDGLVLYDIQDEGSR
TNEERPFPFMETIDSFTYSREYLSSLSIPKIIYRSVGKYSRAELSQFFTCLSPENELTVF
VGASSVSQEVTMSVGDAYELRREINNDVVLGGVTIPERHKSRGNEHIRVFNKISHGCSFF
VSQGVYDVNASKDFLSDYYYYGKENGIPLVPIIFTLTPCGSEKTLQFMKWLGISIPRWLE
NDLLHSDDILQRSVDCSEQNWNELKDFAEGKGIPVGCNIESVAVRKVEVEASVELLRRVS
EKKPHL
>A0A5B8MCG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloropicon primus|TrEMBL
MKISEKLEECTKNGQVYFSFEYFPPKTEEGVNNLFPRMKKMVSYGPQFCDITWGAGGSTA
DLTQDIATRMQKEIGVETMMHLTCTNMMPEKVTVALEKCKEAGIDNILALRGDPPKGQEK
WEAVEGGFECALDLVKFIREKHGDFFGIGVAGYPEAHPDAICDDPEQFAKNYQGELEYLK
KKIDAGGQMIITQLFYDCGTFLKFVKDCRNIGINCPILPGIMPIQSYGGFMRMTGFCKTK
VPQEILNTLEPIKDNPEAVKKYGIHLATQMCKTLIEAGTPGLHMYSLNQDKAVLGILGGL
GLISIEEPAKNPTPAIEEKKEEEKAKA
>A0A239F1J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Belliella buryatensis|TrEMBL
MKITEYISQAEKTLFSFEILPPLKGQSLKDLCEGIEPLMEFQPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFQVEAVPHLLCGGFTKEETENALIDLNFIGVQNV
LALRGDAPKSENKFVPEPDGHAFTKDLVAQIIGMNQGKYLHEETETGFQTDFCVGVAGYP
EKHFEAPSLKFDLKHLKEKVDAGAEYIVTQMFFDNEKYFDFVKKVRDLGITVPIIPGLKP
ITTLGQITMLPRTFFLDLPDALMDDLEKCRTNADVKQVGIEWAIQQSRELIAAGTPCLHY
YTMSKADATYKIAKEVF
>A0A3S1BM49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Competibacteraceae bacterium|TrEMBL
MSSQAHWSQKNFSCEFFPPITAEGVAKLQAAREKLLALRPAYFSVTYGAGGSTRDRTVEL
VLDTQAHSGIPTAPHLTCIASTQDSVRELLNHYRARGIRRIVALRGDMPSGMRDPGEFRY
ANELVSFIRAEYGDHFHLEVAAYPEYHPQASSPEKDLENFKRKVDAGANSAITQYFYNAD
AYFRFVDDCSRLGLDLPIVPGIMPITNFTQLARFSDHCGAEIPRWIRKRMESFGDDRDAI
RAFGLDVVAGLCQRLLEGGAPGLHFYTMNLAGPTLALCERLGLMAA
>A0A0P7Y7U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium HLUCCO18|TrEMBL
MALLSFRKPGTTRVDAPASHGGIAALIEGYSIEVMPRTAAKVEDFRALLPAGTRVYIAHI
DGTGIDDMVATARRLRDEGFEPMPHFPARSIPGPATLADWIRRYQTEAGVKQGLLLGGGI
ATPRGEYHSSMQLLESGLFDDAGFTHLHVAGHPEGNRDIDPDGGEAEVMAALRWKQDFAN
RSDAQFAIATQFAFEAAGAVAWAERLAAAGIEMPVHLGIAGPAKLQTLIKFAIACGVGTS
LGVLQKRAKDVTKLLVPFEPTELLADLAARKAAGAASNIERIHFFPLGGIAANAAWAIAH
GGDAAQPAAASVA
>A0A3L7JFR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Notoacmeibacter ruber|TrEMBL
MATLQPHAHEDVDPSNGLRLDGANDADVKVSYEFFPPKTEKAEADLWAAVQRLEMLQPSY
VSVTYGAGGSTQERTLATVSRMVRETSLTPAAHLTCVGATCAAVDSLADQLWEAGIRSIV
ALRGDPPSGFGGKYEPHPQGYPYAPELIAGLKKRHDFEIFCSAYPERHPESADWQVELDI
LRRKADAGASKAITQFFFEADVFFEYRDRVANAGIDIDIVPGVMLQPNIAGLSRMAGAVG
VQVPNWYRRMFEGLEEDLLTRQMLTASVATDLCAELYDGGVRDFHLYTLNRADIAIAVSR
ALGESHARIRHRD
>A0A3R8UDF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas saudiphocaensis|TrEMBL
MTSANRPSISFEFFPTKTEAGHEKLLTTARRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKTELRELLNIYKDAGIHRIVALRGDLPSGMGMASGELRYAN
ELVEFIRNETGDHFHIEIAAYPEMHPQARNFEDDLGNFVRKAQAGADSAITQYFFNADCY
FYFVERVRKLGVDTPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMDSIQA
FGTQVISEMCEKLLAGGAPGLHFYTLNQAEPSLAIWENLNLNR
>A0A0M8ZZZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melipona quadrifasciata|TrEMBL
MKKFVVEHKVRDQWIDHECDNNTNYFQFKNIKCQMIDLRKTLKNTINTNAISCSFEIMRV
ENNDVYQRFFTEVNKYRPSFYTLTWHIKNDMKDYLSLDVFNALPNNTLLHLIANDLTATD
VKIMLKKALERGIRNIFVLRGDSTKSNGEFPHAVDLVRFIRNQFDDIFCICVAGYPEMHP
ESSSKEMDLIYLKEKIDAGADFIITQIVFEANIFIEFVNDCKKIGINVPIIPGIFPILNY
MCLQKMAKICNIKVPKIILNTLECIKDNNEKVQNYAVEIATNIIKEIIASKTTCGFHFFT
LNK
>A0A1C6J9J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Eubacterium sp|TrEMBL
MKNDGMDEMNIREYLENHKLLTDGAMGTYFDTVEKENYICSEEANITNPSLVRQIHKNYV
KNGAQLLRSNTFLANRETLLSLQKNRAEQFQNVSLKELVTKGYRLAEEVAKEAYSESYPV
FPAADIGPILEEKESEETDILQQYYEICDSFLEAGANIFVLETFPDTEYVLKMAEYIRQI
CPEAFIIGQFSLTPTGYSRTGFHYKTILRDAVQSGLLDGAGLNCGIGAAHMKRFLEAYIE
EYGVPEDMILTALPNCGYPQIVRGHAIYSDSVTYFSEKIKEVSELGVRVLGGCCGTTPEY
IGEIYRTLFQAEHTLKVPTRIVWTDAAGRIQKRQEQLAHIKSAEGKNKTIKKEQVVNTFR
RKLEKGELVCAVELDPPFDANDTKLVNGAKELLSTKADIITIADSPLARSRADASLMAAK
IKMQTGMDVMPHLACRDKNRIAIRSGLLGSYVNEIRNYLFVTGDPVAREDREFTKSVFDF
NSIRLMKFAQSMNQEIFADDMIFYGGALNQNGASPENIAGRMIKKIEAGCSYFLTQPVYD
EEGIKRLAFLKERTGAKILIGIMPLVSRRNALFIKNEMPGIYVPDRVVEKYKENASREEY
EEAAVEISKEIIEMGKEVGAGFYFMTPFNRVSLVKSILEYV
>A0A7U7EE85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARRLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKAELRELLNLYKSAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVQTPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A7K1W869|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. YIM 132580|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRIESVRPSFVSV
TYGAGGSTRSGTVRATQQIAADSTLTPVAHLTAVSHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWESDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFSRLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A0U9HEQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidanaerobacter syntrophicus|TrEMBL
MKVTDIMKKRMSFSFEVFPPKAEQSMEPLLDTLEHLYAYKPDFISCTYGAGGTNVGRNME
ICKAIKESGKTIPVTHYTCIGNKKEKIREELETYLKMGVNHILALRGDFPKGWQETRGDF
DHANELVEYIRTNFPEFCIAVAGNPEKHIQAGSLKEDIAHLRLKQDAGGDYIMTQLCYDV
KNYQCWVEQIRKAGVTLPIDAGIMPVLSKDPTIRMTVSNGCSIPKELAEIIGKYGDSPED
FKKAGKEYTVKLIYDYINMGIDGLHIYTLNKWQDVADIIKNAGIRSIKE
>A0A8E4DJK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKAELRELLNLYKSAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVQTPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIQSIQS
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>R9C0Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niallia nealsonii AAU1|TrEMBL
MSFLDRLKNEILIADGAMGTLLYSYGKDTCFEALNLSHHEQIQHIHQAYIHAGADIIQTN
TYAANYLKLQRYGLEDNVKEINSAAVKIAKQAATTNKVNILGTIGGNRGMKPQAISLEEL
KRSFREQLYCLLLEGVDGILLETFYDLEELETVLQITKKETDLPVIAQVSIHEIGILQNQ
SSLSSAFDRLENLGADVIGLNCRLGPHHMIASLEQIPLPKHAYLSAYPNASLPTYIDGKF
EYKDNAEYFRKSAEEFRKQGVRLLGGCCGTTPEHIKNFAEALKDAVPITEKAIPSNANAP
RVESILLNSPPLREYTPLEEIAKERASVIVELDPPRKLDTTRFFEGAKKLKEEGIDAITL
ADNSLASARISNTAIGTLVKQNIGLRPLIHIACRDRNMIGLQSHLMGLHTLGLQDVLAIT
GDPARVGDFPGASSVYDMTSFDLISMIKQLNEGLSFSGKNLGQKTAFSVSAAFNPNVRQV
DKAVKRLEKKIECGADYIITQPIYSEEKIIELYEATKHIDKPIYIGLMPLTSSNNAEFLH
NEVPGIKIDDSIRQTMANLKDNPEQATQEGLKITKSLIDTAATYFNGIYLITPFLRYELS
VELARYTKRRTAATRRTTNATNFIS
>A0A1M5G565|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides luti|TrEMBL
MTQKYVFFAIFATICIFSGINVAIEIRPMKVIELIKSNDKTAFSFEILPPLKGTGIEKLY
ETIDTLKEFDPKYINITTHRSEYIYKELGNGLFQRSNVRRRPGTVAVAAAIKNKYNITAV
PHILCSGFTQEETEYVLLDLQFLGITDLLVLRGDKAKHEPVFKPVGNGYYHAIELQEQIN
KFNKGVFVDGEQMKVSLQPFSYGVACYPEKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLF
YDNKKFFEFVDRARKAGVTIPIIPGIKPFSKLSQLSMVPKTFKVDIPEDLANEAMKCKND
ADAKQLGIEWCVEQCRELMAHGLPSIHFYSVGAVDSIKEVAKLIY
>A0A1G7CSI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limimaricola pyoseonensis|TrEMBL
MTRPAVSFEFFPPKNIEGSFRLWDTVQALAPMGPEFVSVTYGAGGTTRKLTHEAVDAIHK
KTDLRVAAHLTCVDATRAETLEIVDAYAKAGVEEIVALRGDPPKGSGQFQPHPEGFAGSV
ELIEALAARGNFRIRVGAYPERHPDAAHEWADVEHLKRKFDAGAHSAITQFFFDADTFFR
FRDACEKAGIDRPIIPGILPIENWKGAKKFAGLCGASIPQVVHDGFEHAANQQEADLLAT
ALATELCDKLIAGGAEHLHFYTLNKPDLTRDVCHALGIHSKATLSEVA
>A0A5N4DC95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Camelus dromedarius|TrEMBL
MDRPKPRVPAVGPCCPSRGMRASEAGSARFSVPPCISRNSAMVNEPRGNGGPNPRSEGSS
SGSESSKESSRCSTPGLDPERHEKLKEKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYAADLVKHIRGEFGDYFDICVAGYPKG
HPDAESFEADLMHLKEKVAAGADFIITQLFFEADTFFRFFKACSEMGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCRELLESGLVPGLHF
YTLNREVATMEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGKELTSEESVFEVFVRYLS
GEPNQDGYKVSAAGMGVLPASPRPVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQ
PNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETTEALLQVLKKYELRVNYHIVDVKG
ENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGKLYEEESPS
RMIIQHIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRAPQNEREMEAP
>A0A2N8S3W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MSTSPRPSISFEFFPTKTDAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDTKAELRELLNIYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDQFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRQLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>R9AXK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter tandoii DSM 14970 = CIP 107469|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSNDHFHIEVAAYPEMHPQAESFDLDIQRFCDKANAGANAGLTQFFFNPDAYFYFV
DRIQKEGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A2N6T666|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium tuscaniense|TrEMBL
MTEGHFSSRLSASAPLDLLDEAAETLPTEHTHRAGTALSFELIPPRHDADEAKLNDLIAG
LNAYEPDYVAVTSSHRSGWLEGTADFIARLNAQTNLRTIAHLACTAGTEEELADWIRRLI
HSGVRGFLALRGDLPEGETSLPDGYLQYATQLLTLIQDIEDENAYRLAAGKLALSVACYP
SGHAESATPDLDLDVLLSKQRLGADFAITQLFFEAEDYLRFVEQSRMAGVRIPLIPGIMP
MTSLKRAQRMGVLSGIEVPERVVEKLQNAEDEYEAGMELTVELAAKLLDAGVGGLHIYTH
NNLAVTQDLLSRLGIEPKN
>A0A511YZ21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinotalea fermentans|TrEMBL
MTTTSGAGRPGPTGVAACVADPARPSVSFELYPPRTPAGMTSMQRAVEQLAAVGPDFFSV
TYGASGSTRETSREVVRWLKANTDADVVAHLTCVGVPWAELRQTAEGFLEEGVRDLLALR
GDPPRGVATWEAHPEGLTSGSELVARLRELGREHAVPLSIGVAATPSAAWAAPGQSAEPG
RDDVLALLAKQDAGADYAITQVFFEPQVYAGYVAAARAAGVHIPVLPGIVPLVDPARLRR
LQEISGVPVPPEILVRLDLSDGDERVVVGRRLGVGLVERLVEAGAPGVHLYTFNTHLASL
DLLAALHLPVPRRA
>A0A7S8MWA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium schleiferi|TrEMBL
MANPKTSTSTESAKRLVEGYSLEITGKEKDVVGLTEAASLIPAGTKVNVTFLGNEDLPMR
VSAAKAVKELGFVPVPHISARRIASQAQLEEFLSALAEIGATEHVFAVGGDPATPEGPYP
DALTMIRSGVLQQYGVKEVSIAGYPEGHPDIATDVLWQHLEDKSAALKDAGLDAVILTQF
SFDTDPVMAWIKGVRDRGIDTQIRLGTPGPAGIKRLISFASRFGVGANAMIVKKYGFSLT
NLMGSAGPDTFVTDLAGMFDADPSVGAVKLHMYTFGGLEATATWARDFIAK
>A0A523QV23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MTVQSNLEKVLNEGTFAVTGELGPKRGVDTEHLRKMAELMKPYCDAFNITDNQTAVVRMS
SIAAGIMIKQMDMDPVIQIVTRDRNRLAIQADVLGASAHGIMNVLALTGDHQTMGNHPGA
KNVHDIDSIQLIQCLKGMREGRFMNGEELETDPPHLFIGAAANPFGHPLEFRVTRLAKKV
KAGVQFIQTQPIFAMDIFKKYIEDARNRGLLEKVHVLAGIIPIKSIGMAKYMRDHVAGVI
VPDEKIERLQKAPEGIEEKKERIKKIREEAVKMSVDEVHEALEIPGVHGVHIMAVAWEEI
IPEIVKQAGLDKERPKYKT
>A0A7C9HP80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter gilvus|TrEMBL
MALRVPISFEFYPPKTDEQRTQLDRTAGRLKTRSPDYVSCTFGAGGSTLSYTPETVQRLR
EAHGLNAAPHISCMGGTREELRSLLKLYRALGCKRVVALRGDIPSGMARMGDFRFASDLV
EFIRAEHDGFFHIEVGCYPEMHPQADDPFADLRHFKAKADAGADGAITQYFYNADAYFRF
VDDARKLGITIPIVPGIMPISNFTQLRRFSESCGAEIPRWIGKRMQAYGDDSESIRAFAA
EFVAQLCSRLIDGGAPALHFYTLNLSKPTLNVIELLD
>A0A351CEZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MQLKRKFDAGEFAVLAEMEPPKGVDVSTMVTHAKRVKGDVDAFVVPEMSNAVMRMSSLGG
AVILQSKGMETVIQLNCRDRNRIALQADLLAAFGCGITNVMAVTGEDPSYGDHFQARSVY
DIDLLGLLGAIKGLQEGKDMAGIELSGAPEFLVGSTVNAGAKGKSTELVIEEMNKEIEAG
VQFFISPPLFDLSAIEPFTKRVDIRKTKIIPTVLLLKSLGMARYIMRNVNDVYVPDSLVN
RIQKSPDKVRECTLIAAELVSILKKQGFSGVHIATLGWEHKLPEILERI
>A0A3D6BZM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
PGMDVPDEVIKRLEGVSKEQQPEEGIKMAIEQMERMKEIPGVAGFHIMAIEWEERVAEIV
EGAGLYPRPQV
>H0TUM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. STM 3843|TrEMBL
MTELLTPISNGHVGLLRPKISFEFFPPKTEEMEKTLWASIERLAPLEPNFVSVTYGAGGS
TRERTHATIARILKETSLLPAAHLTCVGASRGEIDEIVDRYHDVGVRHIVALRGDPPGGI
GTPYYTHADGYQRSPELVAGIRKRHPDMEVSVSAYPEKHPESSTFDADIDMLKAKVDAGA
TRAITQVFFDNDLYFRHLDRVRARGIDIPIVPGIMPMHNFKQARGFVTRAGTTVPNWLAE
KFDGLDDDPETRKLVAATVAAGQVQKLAKQGVDTFHFYTMNRADLVFAISHLLGIRPKLG
KKVAA
>K7SIH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidipropionibacterium acidipropionici (strain ATCC 4875 / DSM 20272 / JCM 6432 / NBRC 12425 / NCIMB 8070 / 4)|TrEMBL
MLSTTSPAETIAELLTRAERPLTSFEFMPPRSEEDVYRLWRATDELVPLRPDFISVTYGA
NGSRRDRTLRCTQHMVASGLRTVGHLTAVSQSVAELEQTVSDYHDAGVDHILAIRGDMPG
GAAEPWVARPDGLANATELVRLVKRVNPGACVGVGAFPDCHPASGDLDLDARIVAEKAEA
GASFAITQLFFIPEHYTDLVARVRALGCGIPIIPGIMPITSFSQIRRFGELSGTDVPADL
VARLSEVAEDRAAVREIGLEAAARLSCRLLDEGAPGLHYYTLNRSRATTELHAMVRDRRP
GLWDR
>A0A641UN27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides ovatus|TrEMBL
DLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKPFKKLSQLSMIP
KTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHFYSIGAVDSIKE
VAKIIY
>A0A401YAV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. LS1|TrEMBL
MAELIGGGDRSFSFEFFPPKDAEGEERLWRAIAALEPYQPTFVSVTYGAGGSTRDSTVRI
TSRIAHETSLTPMAHLTCVGHTREELECILDTYAEAGVHHVMALRGDPEGGPRGEWTPTP
GGLTHADELVALAHRRGDFRIGVAAFPEGHPSAESLDHDADVLVAKARAGAEFAVTQMFF
RAADYFALVERVRDRGVDIPIVPGIMPILNLSAIRRQGELIGAEVPPEVVERISAHDGDA
AAVRAEGIAVAAELCEELLEGGAPGLHFYTLNFSKATLEIFAALNVTC
>A0A482WTB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Laodelphax striatellus|TrEMBL
MRRIIRDYSCQWNGLLHSRMLLNWMPALKNKNVLANKACFSYAKDLVLFIRNNFGNYFKI
FVAGYPSGHSDILDRNIEIQYLKDKVDAGADYIITQTVFNASEFVSYVKRCRKIGINVPI
IPGIMPVQNAKLLLRLDNRCKFHFTEDVYNALITYKDSEEYLIEFGIQKAKETILEIVKS
GIEVQQVHFFTINSPEPTMQVWEEVKEAYSKFRVDQSQ
>A0A7C5MWT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp|TrEMBL
MRTTQPEKRKSRLSGSKSPKIEMSFEFFPPKSEKAEQHFWQSLEKLAPLDPRFVSVTYGA
GGSTRERTLRMVRRIAAETGIEAAAHLTCVDASRDEVDEVVRGYKEAGVRRIVAVRGDPS
NGVGEKFTPHPTGYANAVELVAGIGKIGDFDISVAAYPEKHPESANWEQDIDNLKRKRDA
GAARALTQMFFDNDDYWRFLERVEKAGLDMPIVPGIQPIHNFSRISAFAAKCGASMPEWI
SSRFEGLEEDPQTHALVAASLAAEQVTELVDGGVTQFHFFTMNHASHVVALARVFA
>A0A1T4WIJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiothrix eikelboomii|TrEMBL
MTSPILSFEFFPPKTPRMERTLWRNIGQLEMLKPAFFSVTYGALGSERDHSLDTVFNMQR
ECQVPVAAHLTAAGHTRESLLALATRFKEQGVQRIVALRGDADLTEGGLSEVADMVQALH
TIADFDISVAAYPETHPKAANLAADIQQLKRKLDAGAKRALTQYFFEPEMFLRFRDAAVK
AGIQQSLVPGILPVHDFDKVISFSARCGATVPNRFHSIFEGTVAGSQEQKKLGIELAVDL
CEKLMAEGVNQLHFYTLNIPSLTFEVAHQLGLPLAWDEQPHLKIAA
>A0A167PGJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporothrix insectorum RCEF 264|TrEMBL
MHVRDMVAEAEWNGRPSFSFEYFPPKTAQGVQNLYERMERMHLFGPKFIDITWGAGGRVA
QLTAEMVTQAQTYFGLETCMHLTCTDMGVAAVDDALRRAYQAGCTNILALRGDPPRDKDT
WEAVDGGFRYAKDLVAHIRQTYGDHFDIGVAGYPEGSDDNRDEDALLDHLKQKVDAGATF
IVTQMFYDVDNFLRWLGRVRERGITAPVLPGIMPIATYASFVRRVQHMGCHVPPAWLAAL
EPVKNNDDAVREIGKTLVAGLCRRILAHGDVKHLHFYTMNLAQATRMVLDELGWLPTADR
PRPPPALPWKQSLGLGRRDEDVRPIFWRNRGKSAPRSVADVAALFVRYLTGALPTLPWSD
APLTREADTIQADLVALSRRGLLTVNSQPAVDGVPSSDPVHGWGPPNGYVYQKAYLELLV
PPALYGAVRDRVRAHPDLTFHAVTWTGTLETNAPTDGPNAVTWGVFPGKEIVQPTIVESI
SFLAWKDEAFQLGADWARCYEPGSPSRALIRKMMDEWHIVTIVNNDFHKPRTIFEVLAGL
ELADIDKEVEGNPEEAAAAAAAATTATGTTTTTATTSDAVGAAAKLAANSVHDVPEAPKT
PDLANKPQEAAAAGAA
>A0A2W5YQ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MHISDIIQAGSPTFSFEFFPPKTAAAAESLYQTIRELEEYMPHFVSVTYGAGGSTRDLTH
DLVERIQNTTKLDPIPHLTCVCHSEAEIESILQRYAKSCIGNILALGGDPPRERAYDKSG
DAFQHATDLVKFIRRFNESGAHPDPRGFGIGVAGFPEGHPTTPNRLVEMDHLKAKVDAGA
DYIVTQLFFDNRDFYDFRERCDLAGIRIPIIAGIMPITSMSGCKRIADLAGGARFPAKLL
RALHRCEEEPEMVTRVGVHFALEQCHDLLDNHVAGIHFYTLNRSDATRTIFDSLGIPRQR
SAQTPIA
>A0A4Z1J9L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryotinia narcissicola|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRAIDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDGFEQKLRDHPSGAFKDIPIIPGMMPIQSYQMI
KRTTKLSHAKLPSTIITRLDAVRGDDEMVKKVGVDILSEMVEHLKSTKSKYSGPRGFHFY
TLNLEKAVSFILERTELIPDAETVAALEPEYVPTIPDIADLMSIHSGSHKRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGPKNGFVFQKAFVELFL
PTADWKTLHAKLTSPELRDTVSFYASNSKGDFVSSDEAVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKNSETRKIIDGIKEDVWLVNIIHHAYVEGEGLWDV
LLN
>A0A2H0AFD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG23_combo_of_CG06-09_8_20_14_all_60_8|TrEMBL
MLVRDILKQEKLSFSFEFFPPKEEAQWEKLFQAIADLMPLKPSYVSVTYGAGGSTRDRTH
NLVVRIQQETDITVVSHLTCVGSSREEMLAILRKYDASGVHNILALRGDPPRGVTNFQQP
ADGFGHAAELVAFIKQHFPHFCVGVAGFPEGHPETPNRLREIDHLKAKVEAGADFIVSQL
FFDNRDFHDFRARCELADIKAPIIAGIMPITSRNGMMRMADLAAGARVPARLLRAIERAG
SDELIQKVGVHWATEQVRDLIDHGVRGIHFYTLNNSRETLKIYEALGVRDSRQLSA
>A0A1X3S0U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lonsdalea iberica|TrEMBL
MSFFHANHQEALNQSLAELQGHINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKAIKERIGVDAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPPDGGKPELYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRVPNWMTAMFD
GLDHDPETRKMVGASIAMDMVKILRREGVKDFHFYTLNRAELSYAICHTLGVRPAIAA
>A0A2T0YIM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Laceyella sediminis|TrEMBL
MGKPNLIERLRSELLVGDGAMTTYLYQQGVSIGDCTEELVLSDPKLVVGVHQAYYEAGAR
VIETHTYGANRERLTRYGLEGKVTRLNREAVRLARESVGDDAYILGSIGSICAGRMPAYD
EEEYRDMYEEQATALLHAGVDGILLETFLDVKEMLLAVEVIRPLTKLPLLAQFSMLEVGR
TRDAFSISTAFQLLAERGVDGVGLNCRLGPMELLRGLEKTVVPEQLVITAFPNASRLGIT
DGELAYKSNPAYFEQTAELLVEQGVSLLGGCCGTTPEHIRLLAQSLKGRKPVPRRNPQNR
ETAQPVAVEITERVKPTVVEKVRHKRTIVCEFDTPKDLDISAFLHGASRLHQAGVDAITM
ADNSLATARMSNLALGAILKEKMGIEPLVHVACRDRNLLGQQSHLMGLHALGIDQILVIT
GDPTRMGDLPGASSIYDVTSFELIRMVKQLNEGISFAGRQLKQKARFVVGAAFNPHVRQL
DAAVRRLEKKVEAGADFIMTQPVYDAQGIIDVHEATKHIPIPIFIGIMPLTGYRNALFLH
NEVPGIKISPEVLKRMEQQPDKAAGRREGVAVAKELLEVALSRFNGIYLITPFSYWQMSE
ELIRFIHQYDSQHIALRA
>A0A1U9YTX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus larvae subsp. pulvifaciens|TrEMBL
MRPDLRLALQHQLLTGDGAMGTYLYQLGFPVGISYEELNLLQPQVIADIHRRYYEAGAKI
IETNTFSANKEKLSKFGLEQEVKRINRAGADLARQTVGDDAYVLGAVGSIRGSKRKNVLE
ADVRIAFHEQVEALLEASVDGLLLETFYDLDELLIALRLIRNLSDLPVICQFTTEGNHTT
HDGIPLQEAFERLKDEGADVVGFNCVSGPNGIMQSIGRIHPLEQVPFSVYPNAGIPDYVD
GRIVFGATPEYFAETALRFADLGARIIGGCCGTTPEHIAAISKALRGYVPSAEQAFRLRG
TETGRDEEHPVISTGTAETGDSSYMDGVPNLVDLVQQRPTVIVELDPPRTLDINKFMVGA
KALKDARVDAITMADNSLAVTRMSNLALGALVQQRLNVRPLVHIACRDRNSIGTQSHLMG
MDALGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNKGLAFSGKPLKKKARF
VIGAAFNPNVKYLEKAVQRLEKKIAAGADYIMTQPVYDHALIERIHESTKHMDVPIFLGI
MPLASGRNAEYLHNEVPGIQLPDETRGRMAGLEGEAGRAAGTEMAKELIDTALQYFNGIY
LMTPFLFYDMSVALTEYIWGKTSSRHPLLSRV
>A0A2Z2LMT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diaphorobacter nitroreducens|TrEMBL
MSLSTAFPVSFEFFPPKTPEGADKLRAVRQQLYARRPEFCSVTYGAGGSTQAGTFGTVRE
ILAEGVSAASHFSCIGATKDGVRAQLAELKAMGVKRLVALRGDLPSGYGIGGEFHYASDL
VAFIRAETGRDFHIEVAAYPEVHPQARSSDADLQAFATKVRAGADSAITQYFFNADAYLR
FVQDVRRLGLDVPVVPGIMPIMGASQLLRFSDACGAEIPRWIRLRLQGYGDDVASIRAFG
LDVVTHLCEQLRREGVPGLHFYTMNQSAATLEICDRLGL
>A0A6N2YTA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium limosum|TrEMBL
MVNKMSSLLQQTLEAGKFAITAEMAPPKGTDFSHILEIADLLKGRVQGVNVTDYQSAAVK
ASSLAMCVELEKKGLESILQMTGRDRNRIAIQGEMLSAGHFGVKNMLALTGDHTTTGDNP
EAKPVFEMDSVSILQTAEVLMSGQDLAGNELKGAPDFYLGACVTPVFDPIEVQLIKMRNK
IKAGAKFFQTQGVFDIEVMREFKELTKDMDCYVLAGIIPLKSAGMAKFMNRSVPGISVPD
ALIERLTEAEDKAAEGIRIAGEFVAQLKEEGVCDGAHIMAIGAEENVPKILDVAGL
>A0A0R1FAW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loigolactobacillus coryniformis subsp. coryniformis KCTC 3167 = DSM 20001|TrEMBL
MSFKEALQQQVLIADGAMGTLLYSQYDVNSAFEGLNLTHGGDILKIHQAYIAAGADVIQT
NTYAANRIKLNRYGLADKTKAINEAAVSLAHTAQIAAEHPVYVLGTIGGIAGVTDTEIEP
LTAEEIDAGVQEQATYLLQTQAIDGLLLETYYDINELKRALKIVRALTDLPVVANVTMYE
PGVLQDGTPLNTALQDLAALGADVVGANCRLGPYNMSRAFESVALPKTAALAIYPNAGLP
DVQNGKTVYDSPAEYFENYSDTFRRQGAHLIGGCCGTTPAHIKGLVAGLQSRQPVTTKKV
TLPAAEAVPTAADPRQHDFLQRVQHEKVALVELDPPKTFTTAKFFRGAQTLSQAGAGAIT
LSDGPLANPTISNVALAAQLKYQYGITPLVHLTTRDHNLIGLQSEIMGLHTLGIANILVI
TGDPAKVGDLPGATSVYDLHSVELMQMIKKFNAGISPTGRNLQEKTNFAVGGAFNPNVRN
VERACKMITRKTAYGADFIITQPIFDITKVHELRLALDEQGITTPIFVGVMPLLSFRNAN
FLHHEVPGIRLADDTLARMQQAEADGNEREVGLQIAKETIDAICADFNGVHINTPLRHHE
ISLELLNYVQAKNAVSV
>A0A496BH10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MSTSNPLSKIDFLAALSHQILVCDGAIGTELRKRIPAHLQCPDACNIDDAYAPVVAEVHR
AYRDAGADVIQTNTYQANREALAHHGLAEQVAEINRVGVRLAREVMGETGYVAGSVGQLP
FQPQALPSTKAMRRFFREQMDALVDEGVDLLLLETFVSPKQTEIATKQALTYGVPVITEI
SGISGGTVGAGVDVRVFAQELEQLGAHAVGLNCRGPHDLVEAMELLAPVIRVPLVVQPNA
GNPRVEQGEIALSYTVDAEIFGDYVRKLVELGANMIGGCCGTTPEYTARIRRIVARQAPV
QRETRIFVLPKPPGFLYRAKNSVDDGLRREPSHLQSYSPHALHQYKKIENPVQQVFETRE
RIVSVETRANTFPQLRALLKEAKALAAVGVDLFDVTDNSGAVVNIGAVGTAYRLQQATQI
PTLIHWTTRSRNLISMQSHLLEAETLGIRGIVALSGDHPKVGPYETASLVPDVRGAVQLM
KLIARLNRGELADGSSIGEPCAFYYGGGFTIAENLGPHVKHLASKVAAGARFAYTQPVWT
FEDITRAQKAAAHLGIKILYGILPLTSFRSASYLRDNLGLYIPQLIVDKFRDLGDTAAHE
LGMKLTLDLVREIRHQDSVPVDGIYLIPPARMNWKNRRRVITEIVEVYRAS
>A0A7Z1BA79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia contaminans|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A259S1F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. 14-71-5|TrEMBL
MSFDAPPFAPAGAVVPRVPISFELYPPRTTAPIEALHETIQQLASAAPRFISVTYGAGGS
VGGRSLDVLRYIREHTAVEPLAHLTCVGNTYAGASRLIREFLDAGILSFLALRGDPPLDE
SQPFLGDLESSAQLV
>A0A2M7FRA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium CG17_big_fil_post_rev_8_21_14_2_50_60_13|TrEMBL
VSAILAEGVPAASHFSCIGATRARVREQLATLKAMGVKRLVALRGDLPS
>Q6FU20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)|TrEMBL
MKITQKLADRHKEKPDKATFSFEYFVPKTTQGVQNLYDRMDRMYEASLPEFIDITWNAGG
GRLSQLSTELVATAQSVLGLETCMHLTCTNMPISQIDEALEDAYNSGCQNILALRGDPPL
NAPNGWQPIEGGFNYAKDLVKYIRAKYGDHFDIGVAGYPEGHPEEKERHKDLVYLKEKID
AGGSFIITQMFYDVDNFIQWCHEVREMGIDVPIIPGIMPITTYAAFLRRAQWGQIKIPQA
FLDVLEPVKDDDQLVRDKGSELIVDMCQKILNSGYVKHLHIYTMNLEKAPLIILEKLGLL
PSESEVNANPLASLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAMDEFPNGRFGD
SSSPAFGDLDLCGSTLIRQSGKKSLELWSTPKTIEDVSQLVISYLTGQIKCLPWSDTSLD
EEIDPILDHLLDLNRKMIITINSQPQINGIRSNHKVHGWGPKDGYVYQKQYLEFLLPNEK
VEKLEKQLAGNEMLTYFAVDNKDNLKSNHPDGSKANAVTWGIFPGREVLQPTIVEKVSFL
AWKEEFYRILEEWKWNFQENNELKSAEFIQHIIDNYMLVNIVDNDYISSTDEIYNVLINL
>A0A1Z8ZP51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium TMED87|TrEMBL
MSFNDHRKNNQFSLINNVPLGIKVSFEFFPPKNSKMNERLWFAIQKLAPLSPXFVSVTYG
AGGSTRKLTHETVVKIQKETDLTAAAHLTCVSASKEEVDDIAKNYWDAGIRHIVALRGDP
PNNQKAFIPHPNGYKFASDLVLGLKKVADFEISVAAYPEKHIEAHXKEDDLDNLKRKIDN
GATRAITQFFFDPDIYLRFRDDAXKRGISVPIVPGLMPITNFEQNIEFAKSCGADVPKWL
LNLFKGVEEDDEARKLISGTIAVEQVRRLVENGVNXFHFYTLNRPDLTFAICRVLGIKSN
LIXKLNDC
>A0A560WR45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. AEW013|TrEMBL
MTLNDPAAPLYADLAGDCHVSFEFFPPKTEKMEAQLWSAIETLTPLQPKFVSVTYGAGGS
TRERTHNTVARIARETPLAAAAHLTCVGASKAEIGEIADAYWEAGVRHIVALRGDPPEVG
GTFEPHPEGYKGAAELVEGLMQRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFTPDAYFRFLDKTLAAGITADIVPGIMPVSNFAATQRMAAMCNTQVPSWMGRLF
EGLDDHPASRQLVSATIAAELCRSLYGGGVRDFHFYTLNRAELSFAICHLLGLRATASNG
GTA
>A0A1Y1IUE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas testosteroni|TrEMBL
MTAEIAQTAARLVVEEGLEWGPAKQRAVRQLGLPGRTALPDNDQLEEAVREYIELFCGDT
QPQELQALRELALVWMDRLQEFRPHLAGAVWRGTATRLSDIYLQLFCDDPKSAEIALINN
HVQYEPSTVTGFQGKPVEALSVHALCKPINETVGVHLLVYDHDDMRGAMKPDSHGRSPRG
DAKALRKLLQESCDE
>A0A3A9VZU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimarina sp. BL5|TrEMBL
MKVTDHIKKAKGKTLFSFELIPPQKGRSIQELYDNIDPLMEFDPPFIDVTTSREEFIYID
REGLLDKKLTRMRPGTVGICASITHKYNVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFNPTKGGHCYANELVEQIVNMNNGRFLHEVIESDNQSDFCIGVAGYP
EKHMEAPSMDSDIRRLKDKVDAGADYVVTQMFFDNKRYFAFVEKAREAGINVPIIPGIKP
VAVSRHLQLLPQVFKLDMPDELVRAVESCKTNKEIRQVGIEFAIQQSKELMEYGVPVLHY
YSMGKSDNIKKIASEVF
>A0A0K9UQY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cholerae 2740-80|TrEMBL
MGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQNIVALRGDI
PAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPNWMVKQFEG
LEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A3R5Z9S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. OF03-24|TrEMBL
MRLTELLNTENVTISCELFPPKQGAQLDNYKKIVGDMAALKPAYMSVTYGATGGTSDYTV
ELANEVRNVNHIPALAHLTCASSTKEKVASVIQELKEKQIENVLALRGDIPQNADFPLPN
QYKHASELIYDIKSQGDFCIGGACYPEGHPESQTLEEDLIHLKEKVDAGCEFLTTQMFFD
NNILYNFMYKALKHGIDVPVVAGIMPITNANQVKRSIALSGSLVPRRFLAIVDRFGSDPA
AMKQAGIAYATDQIIDLIANGVNHVHIYTMNKPDVAGAILENLSDIYVRD
>A0A2D8RJU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutaceae bacterium|TrEMBL
MFEQKPIIDLLDSSVPTLSVEFFPPKSQDGVESLVDAASRIASRKPDFVSVTYGAGGSTR
DLSASVSERMKNDIDLQVMPHLTCVGSTKEELATIVDGFYQDGYRNIMALRGDPPKGQEA
FVRTEGGFSYASDLVAFIKSRHPDICLGIAGYPEKHPEAPSMDSDLDTLKVKADAGGSFI
TTQLFFDNAVFFQYMEKVQSRGIQIPIVPGIMPVLSLKQIKRITQLCQSSLPNSLESQLS
KVESDPEAVRRLGVEWAAAQIEDLLANGVPGIHIYALNKARSAIELIDAARR
>R1GZX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grimontia indica|TrEMBL
MGYSHASHLDALNQNLSDLNGDINVSFEFFPPSSEAMEQTLWASVQRLKTLKPKFVSVTY
GANSGERDRTHGIVKSIKQETGIEAAPHLTCIDASRDELREIARDYWNSGIRHIVALRGD
LPEKSQKPDMYAADLVELLKGEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIIPGILPVSNFKQASKFANMTNVRIPAWMYKQYE
GLEDDAVTRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPTA
>A0A8E1QMZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola|TrEMBL
MIDPDTPSLASTITEAYSLEVSAKHIAGLAAAAPRIMRGATIAIPYLPNQDDDARLAAAR
MVRTLGFQPMPHLSARRIASREQLHAFVSRAVDDAGVERCLVIAGDPPAPLGPFPDSLSL
LDTGVFERSGIRTIAVAGHPEGHPSMPAADRWEVLQRKCRSIAERGMAPLIVTQFAFDAD
IVLRWLQALRAHGIAYPVRVGVPGPAGVAVLARYAASCGVSACASMLSKYGISLGKLLGT
AGPDRFVERLATGLTDAHGEVRMHFYPFGGIAQTVAWVEQYRSRSARV
>A0A380XJL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FILLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2N3LGL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Margalitia camelliae|TrEMBL
MNLLDRLKDSILVADGAMGTLLYSYGKDTCYEEFNLSHSDDIYNIHQAYIQAGAQVIQTN
TYGANYYKLSQYGLEEQVKAINIEAVRIAKQAANKGTYILGSMGGYRGFRKADITLAEIK
RSFREQLFHLLHEGIDGILLETYYDAEELFAVVEIAKDEANVPVIAQFSLLEPEVLQNGS
FVKDGLQRLEELGADIVGLNCRLGPHHMIQSFEQIPLPNRSFLSAYPNASLLDYEDGRYV
FTKNAEYFRSCSVRLVEQGVRLIGGCCGTTPEHIKAIAEGVRGLQPVTEKQVKPVRPTVE
VLASRIDKEPPLHQIVKERTSIIVELDTPKHLQTESFFTGANRLKEAGIDALTMADNSLA
SPRISNTAMATILKEQHGIRPLVHITCRDRNLIGLQSHLMGLDALGINQVLAVTGDPSKI
GDFPGATSVYDLSSMNLISMMKQFNEGISYSGKTLGRKTSFSVAAAFNPNVRNLDRAVSR
LEKKVQSGADYFITQPLFNEKQMEEVYESTKHMKVPIYIGIMPLTSYRNASFLHHEVPGI
TLTEQILRVMERVQDDPIQATRESIAISKSLVDTALKYFKGIYLITPFTRYDLTVDCVNY
VHAKEKLVHGTNVI
>A0A850B3V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MNLLETLAQKTILADGAMGTMLHGRGIGFDQCFDELNLTNPAAVAEIHRAYIEAGAEIVI
TNTFGANRYKLTKHGLQGDVAEINRAGVELAKRVVAASFKDVLVAGDVGPLGVRIAPYGR
VKPEEAREAFAEQITALAQAGADLIVAETISDLYEIHEAIKAAKENTSLPVVATITFTRD
DRTLLGDDPVKVAHRLASSGADVIGVNCSGGPAQLLRILKQMRQAEPNATFCVKPNAGWP
EQVSGRIMYPADADYFGDYALLFREAGANIVGGCCGTTPRHIAAMRKSLDASPSSAVIEV
SALPEDEITAEPAEQPTQLAQRLADNKFTVCVEMDPPRGLSTHKLLAGASLLQDSGANII
NVADSPLARMRMSAWAVCDVVQRTLGVETTLHFPTRGRNLLRVQGDLLAAHAIGLRNVFV
VMGDPTSIGDYPEATDNYDLVPSGLVKLIKQGFNMGVDHSGTSIGQPTNFFVGAALNLCP
QDVDTEIKNLHRKVKAGTDFFLTQPIYSPDDGPKLLEAYESKHGKLNQPILAGILPLVSA
KHASFLHNEVPGIFIPEASRARIEAAKDGAAKVGAELAIELIQNIKGWAGGIYMMPQFHR
YDQASEIIE
>A0A847PEF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fretibacterium sp|TrEMBL
MKDFFDIPRPSYTFEIFPPKGSNNLEGTYATIDALASLTPDMISVTYGAGGTSRENTLEI
ASTIQNRYNICGVAHLTCVGSTQENISEILKELKAGNIRNILALRGDLKEPSDLGEFKYA
SDLIRFIRRTQNDFRVFAACYPEKHIEAPSEAEDLRRLHEKTACGVDALISQLFFDNDVF
WRFRDRARSIGIETPIVAGIMPVTSATQIEKMTTMCGASMPERVLRFVNAYGHNSHAIKQ
AGIAYATEQIVDLLARGVDGIHLYTMNQPDIVRSIDENIRGILYSMRVKRD
>A0A1N7A4L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPLFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7X0EXJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea muscovyensis|TrEMBL
MTFQLVCEIEPPTRPDLKRVRHQIGTLSTIAHSFLIPDNHIGRATVSSVAVAHEVQAMGG
RSIACLNSRDRNLLGLRRDLLTAAAYGVEEFLFVHGDKPASGNRAGDLTVRSMIEETREF
SPGVRIGAAAGLRPLPAWKRAADFLFVQVSFSLEALLRWREANQVEVPVYAGVMVLASET
HARRMAAAIPAIDIPDDLVARVAADRMAGVAAACEQVLAIRDSGAFDGVHLVPVSRYRDV
ESRLAGAFR
>A0A8H7EPH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apophysomyces ossiformis|TrEMBL
MKIIDKIRKAEKENRYFWSFEYFPPKTAQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
DLTMEIVATAQSVYGLETMMHLTCTNMPVEKVDIALKAAKDCGCQNILALRGDPPRGQST
WESCESGFEHAVDLVKYIRKHYGDYFCIAVAGHPEGHMDNPSKEDDLQRLKEKVDAGADF
VVTQLFFDVDIFLDFVKRCRAIGITCPIVPGIFPIQNYNGLKRVIAFNDNYVPQKIWDDL
EPVKDDDAAVKEYGINLAIEFVRRFWEAGIRGFHIYTFNLERSSRLILEHLNLVPSLEQI
KPLPWNPSLTSKRAKENVRPIFWKNRTKSYIQRTESWDEFPNGRWGDSRSPAFGELDGYG
VSLKYPTKECLEMWGHPETVDDIALLFARYCKGQLPGLPWSAQQLEPETEIIRQRLAAIN
LLGYLTINSQPAVNGAKSSHPVHGWGPKDGYVFQKAYLEFFVSPEKLDELAEKISRNPQV
TYYAVNKQGDLRTNTQSDQPNAVTWGVFPGKEVVQPTIVESAAFMAWKDEAFELWAEWAR
IYNRQSPSANMILDICNSWYLINIVYNDFQDENGIWRLFDLEIDGAISRKLRQSSVSATH
>A0A6N8GYB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Subdoligranulum sp|TrEMBL
MTITEKFQNKRCVFSIECFPPKQTTQMDKMKATLQAMRALNPDFISVTFGAGGSAGGVST
VEVADYIQHEVGVPALAHLICMGNDQTSAARILDELEQAGVRDVLALRGDRTPTRPESPD
FKHASDLTAFIKWKKPGFSVHGACYPEAHPEAATLQQDVENLRIKQANGAEHLLTQLFFD
NMHFYRFLNLARRAGVTLPVSAGVMPIVKRSQIERTVALSSASLPSEFTRMVSRFQDDPD
SLYEAGIEYAVNQLRDLIEGGADGVHLYAMNDANVAAKVYEGIKDLL
>A0A854DLK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKVISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7S1I3M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eutreptiella gymnastica|TrEMBL
MYVGLMKIIDKLKEGSEEFWFALEFFPPTTDEAVTVLYDRMDRMAELGPMFIAVTCDCAT
PRTMDICSNSQNLLCLDTMVHVSSKDITPEALAIVLKEAKENGIMNLLARHDITSVHDNR
QAEETVELIKNIRAMHGDDFCIGTMGYPEGSRDGTTEEEDLRDLQQIVEAGGDFIITSHF
FDVDRYIHWAAQCRERGIHCPIVPGIMPIGSWEHFQQMTIMNPHVDKTGEWLRVHDHLST
IKHDLVALKQYGVELCTRSIQRLADHGWKGLYFYSLNLENAVTQ
>A0A6P1ZS85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nodularia sp.|TrEMBL
MQDTQNTPVLNSFRRAAQAGEFLVTAEVAPPKGVNVNHMVSMAATLKGRVHAVNVTDGSR
AVLRMSSLVASVILLQKGIEPICQVACRDRNRIGLQADLMGAHALGIGNILALTGDPVKV
GDHPNAKAVFDVESVRLLQLIRKLNQGVDYNEKPLTDGATDLFAGAAVDPQCTSWSGLQK
RFERKIEAGAQFFQSQMITDFERLEKFMDTVAVHYQKPILAGIFLLKSAKNAQFINRCVP
GVNIPQQTIDRLAKAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIVPILDLAGV
RSVNQMVAK
>A0A150B810|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVAEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNATPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A160H3F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGSATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0V0XJD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella pseudospiralis|TrEMBL
LMASLEAVELKTTRHDLNSSPKKSTDKICQPLIDRIKQNMSSGRRFFSLEFFPPHTPEGL
INLLNRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCVLNFCLLDTMLHITSVQY
NEKTVLSNLERVKKIGIRNILALRGDISDDANVTATDFQYACQLVRFIRSHYGDYFTVCV
AEDLLNLKAKVDAGADFIITQLFFDEMHYFKFVNDCRKIGIVVPIIPGILPIQSYQSIMK
IVQLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVELCRKSILEQIGLWKESPVRMLPW
KKHPVHSVRCREAVRPIYWNTRPKSYLCRTRDWKQFPHGRWGDLGNPAFGDLKHYLFSCI
DQMNDSCALDMWDKELSSFEHVRDIFCNFIARTPNRHGHTVRRLPWNENHSDPAVDVLKD
ELIYYNSNGILTINCQVAVNGLPSNDPIFGWGEANGYIYQKGYLEFFASSKCTTILLNHV
QNFPSINYHAINFDGSFETLNYDEDATMALTWGVFVGQEILQPIVANAASFRVWKDEAFD
LWQRWARLYESGSIGRKLLQSIHDDHRLITLIDNDYPQPCSLSALLRANSGRLAPRASKH
GIIAEEEEEEAIIVKSQVVVAVVVNISLGETATPSKTKSTDVSSCFFPHDTLNKSEQCEH
LRTSWLCCLLAAGVVVSAGVAPALFLPEQVESVGWAGRLSLNRLLSFAVGSLIGDVFLHL
LPDIWRSTDAQGVATAGWWTVMGLFFCFSVEKCAVKPDDQHSKRLVAAGLNLLANL
>A0A5R9GXA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariprofundus erugo|TrEMBL
MKLSKILAAAERPLISCEFFPPKTDKGEENLWQCLKELQAINPAYISVTYGAGGTTQDRT
KGIVTRIKQETGLSPVAHLTCVGASKDELAALLADYRAAGIENILALRGDAPEGMDRFEA
VAGGFSHATDLIAFLREQGDFSIACATYPEGHPESKGGVEDDIRYLKLKQDNGADAAVTQ
YFFDNDAFFRFRDACTAAGVTLPIIPGIMPVGNFDQIVRFSSMCGATIPDWLRARMEPIR
EDLDAVKALGIELAAKQCRELLTAGVPGLHFYTLNKSEATIAIHNQLTDLL
>A0A3T0SL32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadaceae bacterium SI-3|TrEMBL
MSQTRSHSFSFEFFPTKTDAGHEKLLATARRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVSTAPHLSCVGDTKAELRELLNIYKDAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARHFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVDTPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMESIQA
FGTQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAVWENLKLVR
>A0A0J8YDI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Franconibacter pulveris|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWTSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRAIARDYWDNGIRHIVALRGD
LPPGSGKPDMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVAA
>A0A2G6TRG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium 23|TrEMBL
MSFPISFEFFPTKTPEGAAKHVQVRKNLYARKPQFCSVTYGAGGSTQAGTFNMVRDIQSE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPHSDLEAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A4R0SFM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A1B2IY14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Secundilactobacillus paracollinoides|TrEMBL
MKVVNCFDHRPVISFEIFPPRANASEKATNRFYASLDTLASLEPAYISVTYGAGGNGNHA
STLALCRYIKEHYGIDAVAHIPAVAFDQQSLKIYLADLEDAHVENVLALRGDLPADGRPN
NDFPFASDLVTAIKRESDLNILGACYPDVHPEADNCVVDVQHLKEKVDAGVSQLITQLFF
ENGHYYNFLERCELAGIKVPIQAGIMSVINERQIAKMATMGGVGLPPKFLKMMHHYQDNK
IAMRDAGIAYAVDQIVDLLSEGVDGIHLYTMDNPVVTQRICSAIKTLI
>A0A524PJZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MANNLSPSISKLAAVLESGRFALAAELSPPRGVSLEAITRQADTLRDYVDVVNVTDNQAA
SVRMASIPTSALLVQQGIEPIAQMTCRDRNRLAIQADLLGAAALGIRNVLCLGGDHGRWG
DHPQAQNVFDLDSIQLIRMVKSMVVDGCLDNGRKIDPAPQFLIGAVANPFSPPYDYRPYR
LAKKVAAGAQFIQTQMIFNVERFRQYMNKVRDLGLDEQVSILAGVGPLRSKTQANYLGTR
VAGIDIPETILERMRKTPKAAQPAEGIRICCEVIEQVREIPGVAGLHIMAVHWADAIPEI
VTRAGLRPSAK
>A0A0G3GQX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium epidermidicanis|TrEMBL
MTDSRVIPNYQRHIVDVLSQPTPGRIPFSVEFMPPRDEAAERRLFDAALVFKDLGVSFVS
VTYGAGGSTRDRTFRVAQQLAQYPLTTLVHLTLVDHPCQQLHDILSTYADAGLTNVLALR
GDPPGDPLGPWTKTADGLEYASELIELIQQHPSCSRFEVGIASFPEGHHRADCLETDTYN
TLRKLRAGAAYSITQMFFDVEHFLRLRDRLIAEDPEHGAKPIIPGIMPITSVRGMQRQVD
LSGASVPAALRRRLHEAEPHGADYVRSVGIELSTELAERLIAEGVPGMHFMTLNNARATQ
EVLHNLGMAPAWGVDKGHDAIR
>A0A524PQC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MTENQTNGYKSGSNLERVLRAGHFAVTAELGPPQNADSAVIREKAKLLKGYCDAVNITDN
QTAIVRMSSIGAGTIVVQEGLEPIIQMTCRDRNRLAIQSDLMGAYALGMRNLLCLTGDHQ
SFGNHPTAKNVHDLDSISLIQMAVQMRDGHCFQCGDEIKGIEPRFFVGAAANPFGDPFDW
RPFRLGKKAQAGADFIQTQLIYNVPRFEEYMAKVRELGLHKQLYILAGVGPLKSPGMARY
MRDQVPGLDVPSEFVDRMLAVTEGMDPEDKKARAQAWRQEGIQIAIELIGQMQKIEGVAG
VHVMAIEWEQAMKPIVEGAGLYPRPEPEPLSTTDAQAA
>A0A0E3YQ50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola|TrEMBL
MIDPDTPSLAGTITEAYSLEVSAKHIAGLAAAAPRITRGATIAIPYLPNQDDDARLAAAR
MVRALGFQPMPHLSARRIASREQLHAFVSRAVNDAGVECCLVIAGDPPAPLGPFPDSLSL
IDTGIFERSGIRTIAVAGHPEGHPSMPAADRWEVLQRKCRSITERGMAPLIVTQFAFDAD
IVLTWLQALRAHGIAHPVRVGVPGPAGVAVLARYAASCGVGACASMLSKYGISLGKLLGT
AGPDRFVERLATGLTDAHGEVRMHFYPFGGIAQTVAWVEQYRSRSARV
>A0A6F8QDM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mameliella alba|TrEMBL
MTGPYPDPPASVSFELFPPKTDAGETALGRAVDQMAGADPAYFSVTYGAGGSTRDRTARV
VDMVGRRSGRPVAHHLTCVGASRDEVDQLARGLHDKGITRIVALRGDLPEGQSLAPDGYG
DAAELVAGLRRVADFDISVAAYPEVHPEAANAEADLDHLKRKLDAGAARAITQYTFDTDV
ILRFVDRARAAGITAPIVPGIMPVANFSGLKRFSAMCGASVPGWLAQMFDGMDDDPATRA
MIATSVATEQCRLLMEAGLTEFHFYTLNRPEISLAVCRALGLTTGPAAESAA
>A0A7C2WJ00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTNLEKVLESGRFAVTAEVGPPKGPSAAVIQRRGEIVRNYVDAVNVTDNQTAVVRMS
SMAGCAILKTLGIDPVMQIVCRDRNRIAIQSDVLGAIALGIGNILCLSGDHQKFGNHPSA
KGVFDIDSMQLIQTLRNMRDEKKFICEEDITGEVPIYIGAAANPYADPFEFRVTRLAKKV
KAGADFIQTQAVYDVPKFRRWMEMVCERGLDQQVHILAGIIPIRSIGMARYMRDYVAGVT
VPDEIVTRLEKAENAKEEGVRIPLEIIEQLKEIPGIHGIHIMAVGWEEIVPDIVEKAGLL
PRPVL
>A0A7C2WJJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTNLEKVLEGGGFAVTAEAGPPRGAVPSVILRKGELLKPCCDALNVTDNQTAVVRMS
SLSGCILLKQLGVEPVMQMVCRDRNRIGIQSDILGAVALGIGNILCITGDHQSSGDHPST
KGVFDLDSIQLIQVLRQMRDDKKFLSGEDISGEIPLFIGAAENPYADPFEYRVLRLAKKV
KAGADFIQIQAIFDVGKFTEWMEMVTDRGLDREVHILAGIIPIRSAGMARYMRDKVPGVV
VPDEIVARMEDAKNAKEEGLKICLEIIEQIKDIPAIHGIHIMAVGWEDIVPIIVERAGLL
PRPVI
>A0A7I7M7I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium psychrotolerans|TrEMBL
MTAELAGERAAAGCPKHMRFGPCGGVRPDGQCEMRPGPCEFPETVLWDGAPAEAQRVAAP
LILTDFSCLPFDAADLAATAGALADSCDAVLVGEHQNRPDFPPTLMGSLLLDAGVQPWIT
LSCRDRNRVVLEQELRGLALTGVRTVLCVTGDGRAYDVRPDVTQTFDLDGPRLVALAAEL
GVTAAVPETPSAPPISGRPLRLVQKQRAGASIAVLNHMSAPAVVADFMAAARAAGLAIPV
LAAVAVITDELSAAVLQGLPGLAVDWGVVDGILNAPDPVEAGIDAAVAEARALLAVDGVD
GVNVSGLASAAGTRAGAEIKAEVGRRIRQGREAL
>A0A8B7W4H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Castor canadensis|TrEMBL
MRPTQPHSCSGPANIESPGTGGPPGGAEATPGPSLLNLLAGEERGGPLALSTPERTESCC
ARISAETPCLAPSNRNPAMVNEARGSGGPHPRSEGSSSGSESSKDSSRCSTPGLDPERHE
KLRDKMKRRMESGDKWFSLEFFPPRTAHGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGS
DKETSSMMIASTAVNYCGLETILHMTCCRQRREEITSHLQKAKQLGLKNILALRGDPTGD
EWEAEEGGFNYAADLVKHIRSEFGDYFDICVAGYPKGHPEAGSFEDDLKYLKEKVSAGAD
FIITQLFFEADTFFHFVKSCTEMGITCPILPGIFPIQGYSSLRQLVKLSKLEVPQQIKDV
IEPIKDNDAAIRNYGIELAVSLCQELLASGQVPGLHFYTLNREMATTEVLKRLGMWTEDP
RRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDY
YLFYLKSKSPTEELLKMWGEELTSEESVFEVFASYLSGEPNRQGYKVTCLPWNDDPLAPE
TNLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVE
ALLQVLRKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFW
KDEAFALWTEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQIVEDTFELL
NRPARNEQETATP
>A0A6J2YS27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sitophilus oryzae|TrEMBL
MPNYWRTWSTFISVTWLGAKYLQLPNHQIPTVVLAQNLNKLKCPVLVHLPGRNLNKERML
EILNLLKNSGIKHVLALQGDWVHVLEKDDTKVDFPYASDLVSFIKGNFGSEFCVGVTAYP
DLHPHCEDLERDLDYLKKKISLGAEFILTQAVFDFDVLENYAKSCRRHGINVPIFVGVFI
IKSYQSLKNMAKWCEFKVPQAVLEFLENNRDDPDAIERFGLDFGENLIRKILENKELFAG
VHLYSMNDMEWMEKVLDKFKYSDDASSSAKMK
>A0A8F8CDF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. AO-1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQVLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A8B7W0N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Castor canadensis|TrEMBL
MRPTQPHSCSGPANIESPGTGGPPGGAEATPGPSLLNLLAGEERGGPLALSTPERTESCC
ARISAETPCLAPSNRNPAMVNEARGSGGPHPRSEGSSSGSESSKDSSRCSTPGLDPERHE
KLRDKMKRRMESGDKWFSLEFFPPRTAHGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGS
DKETSSMMIASTAVNYCGLETILHMTCCRQRREEITSHLQKAKQLGLKNILALRGDPTGD
EWEAEEGGFNYAADLVKHIRSEFGDYFDICVAGYPKGHPEAGSFEDDLKYLKEKVSAGAD
FIITQLFFEADTFFHFVKSCTEMGITCPILPGIFPIQGYSSLRQLVKLSKLEVPQQIKDV
IEPIKDNDAAIRNYGIELAVSLCQELLASGQVPGLHFYTLNREMATTEVLKRLGMWTEDP
RRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDY
YLFYLKSKSPTEELLKMWGEELTSEESVFEVFASYLSGEPNRQGYKVTCLPWNDDPLAPE
TNLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKESQEDWHLTGAAA
RGKGI
>A0A7C4X1L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKTASRLEKVLASGAFAVTSECGPPRGADPEVIRRKGEALKGVVDAVNVTDNQTSVVRMS
SIASCVILKEMGFDPIVQMTTRDRNRIALQSDILGAGALGLNNILCLSGDHQRFGDHPSA
KNVYDIDSVQLIQTVRRMRDEGKFINGQEIKPAPKFFIGAAENPFADPFEIRVPRLAKKV
AAGVDFIQTQCIYNLEKFRLWMKGVVDRGLHEKVKILAGVTPMKTVGMARYMKTSVPGMD
VPDEIIDRLKGAPKGKVGEEGIKICIETIQQLKEIEGVAGVHIMAIEWEEKVREIAEGAG
LLPRPQV
>A0A7X4AV02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKSGSRLERVLRAGHFAVTAELLSPDSADPQAVLDHAQVIGDSCDAINATDASGATTHMS
NVAVAALLRRAGYDAVVQLACRDRNRIAMQGDLLGIAALDVRNVLCLTGDGVGTGDHPEA
KPVFDMDSITLLRTARILRNKGQFLSGRPIDSPPRLFLGGASNPFVPPYDFRPLRLKKKI
EAGADFIQTQYCFDVPRLRSFMERVVDMGLHERAFILVGVGPLRSARVAYWMRENIPGVV
IPDTVIRRLMGAGKRSRTEGKRICIEIIQQIKEIPGIAGVHVMAYRQEHLVPEILDEAGL
LPRPEPALLDGVHTPEVDVVKSSRS
>A0A2E9F198|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MNSSFSERVFQGVLISDGAMGTQLHSRGGYNPNHSLDFLNITNPNLVKAIHLDYISAGAE
MITTNTYRANAPMLTSLGVGEQFNKINAAAVKIAQEARSLSGQQVWIAGSIGPPGKQTDL
FGASSLSNIANTVQDQADVLANNGVDLILLETFPSVADLTEAVSGIRKVTDLPIVAQLTF
MDDKQTPGGDTALDVVAALNESDVIAYGANCSVGPSLLIEILETMISTAKVPLIIQPNAG
FGSYQFGRLVYGSSPSYMAEMTSRMLEIGGTIVGGCCGTTPEHTAQIRDIVHFHKPGKKS
TSKKAAPKTEMTNRKQKQILEPTALAQSFKKGQFVVTLEVTPPRGFDFTPTLNKLRSVSN
SVHAFNVTDSPRAQGRMSALAAASIIQARLGKETILHLALRHRNLLALHGELLGAHALGA
RNIFTVMGDAPNSGDYPQATAISDVTPSGLIKILNGFNDGVDASGRPMEQATKFLIGCAL
DLNSNNMETELRNLDRKINAGADFLMSQPVYDPEKVERFRQRLGGFPLPLLLGVLPLRNT
RHAHFLDNEVPGITIPDQIINRLEKAEENASEEGYIISQEIIKNVRKSIAGVYFIPAFGQ
YDSVNSVMNID
>A0A7C7IIT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MPAKSTTLNQNKFIYTSELTPPKGIDLSKLINTASDLNMIDAFNITDNHNSKMTMAPIGL
ARKLIEHNIEPIYQITCRDRNSMAIQSDLLAAYSLGINNILCMSGESTKYGDHPNAKDVF
DINSEELIETVTKLNNGYDYANNKLDSVTNFNIGAVVNPGSNMLEKELIKFENKIKNGAT
FFQTQAIYNPKTLENIIQIKKDKNIKIFAGYIPVKSAQMANYLNNKVPGIQVPENIINLM
KITDDPQKTCIEISKDIISEIKAMKGIDGVHIMALGWEHLIPKMI
>A0A6L9Y3V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelistega ratti|TrEMBL
MARDNFFSVEFFPPRDVAAAERLQKTTQELQVIRPSYMSVTFGAGGSTQVGTIETVRMLK
NRGLEAVPHLSCVGNTPEQILAYLEQFKQIGVTQLVALRGDLPSGMGLASSELRHASDLV
AFIRQHYGDYFNIKVAAYPEMHPQATSPSEDLDHFITKVNAGADSAITQYFYNPDAYDEF
VNRLTAKGVTIPVYAGIMPITNYSQLSRFSQMCGAEIPRWIRLRLAEFGDDQASIRAFGI
DVVTQLCQKLIDNGVPGIHFYTLNQSKATLAIWQNLKI
>A0A3D5FYA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTQPASSPTSGSFRHLLEETDRFIVAVELETTRGLAMEESSSRTLSLARRLAGSNPVDLI
CITDNPGGNPHIRPEVMGYELLARGQEVVINFSCKDYNRNGIESRLWSLGSLGFDNVLAV
TGDYPITGHAGGPQPVFDIDSVGLLEVMRKMNGGLEIPSRRPGGDPSRLRQTSFFPGVAI
NPFKSTEAELLPQLFKFGYKIRTGAAWAVTQIGYDSRKLDELKKYAAVNDMDIPILGSVY
VLNAPAARVFHHGGIPGITVPDELFELVQKHADSEDRGRAFFEEFAAKQIAVLRGIGYRG
VYLSGRLPLTRIRRILDLEASFGPDDWREFSKEIQFQKPGEFNYYERDQNTGLASDQVNR
EYLESKTAKGMKRARGHVSPAYKAGRTAHGLVFDSAAPASGLARKLYWFADKRRKVGDLL
HLAEQAVKIPMYGCRDCGDCSLPDIAYLCPESQCAKNQRNGPCGGSHDGICEVGDKRCIW
VKAYERTKAYGEEETILDRPVVFKNGALRGTSAWGNTFLKRDHNAPVAIEGNGSENLANP
DAGGSANGSD
>A0A800EFI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTIISERLNQGTTLSFEFFTPKDTAGKDRLDQNIEHLMNFSPDFLSITYGAAGTGRARTI
GWVEGLSTRYSVPIMPHLTCISHTKSEINSLLDIYKLVGVENLLCLRGDKPSDSSLTTTS
DFTYASDLVTTVRHHSEFDIGVAVHTEGHPESANAETDLLHQSAKVEAADFAITQFFYES
RHYEKFTEYLRKRDIRTPVLPGIMPATNLASLQRMSNLAGIKVPPKLIKQLQKADSSLKD
RQEIAIETSVELSEKLLALGAPGIHIYTLNSGIVPGKISQAIEPAIHSAQDHN
>A0A7I8EJ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ktedonobacteria bacterium brp13|TrEMBL
MSTTTTQDPFRERIQHGPILCDGAMGTQLYSRGIAYDRCFEELNTSDPELIKTIHLEYIQ
AGAEIIETNTFGANRYRLLEHSLGDRVQEINRAGARIARDARDLSERPIFIAGNIGPLGV
NLAPLGDVLPEQARAAFREQTEALLQAGVDLFMIETISDLAEMREAIGAVRDVTTLPIVA
MMTFSEEASVASGEDPRTVARVMHDLGADIVGVNCALGPSSTLDIIQTMQEDTDVTIRVA
AEPNAGLPRRVGNRFIYVSTPDYFADYTRRFVDANVCLIGGCCGTTPQHIAAMRKAIDEC
TPELHAENADVLNSQSQVLQLIQLNEYEKDETTPEQPNSKLAQLLHDGRFVVSVEMRPPR
SVKYTRFVQNAAYLRDIGVDLINITDNAMARIRMNNIAAAQLIQQGTGLETIVHFTPRDR
NLMAVQSDIIGAHALNIHNILAVTGDPPSHGDFPHATGIWDVDSIGLIAILNNLNQGMDG
RGDKLAAASSFFIGCAATPTATDIDLDIERLHRKLEAGAQYIMTQPVYDPETFFHYFDLY
KERFGPLHTPILVGLQPLHSYQQAEKFHNEVPGIVIPEHIRQRLHAAGEDSGRVGIEIAL
EMFEAVVPYIQGTYIMPLDRYTLIGDILPTIRERIQASIMVNE
>A0A350AKE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MARKEFPSIIALGYLNPPDSAYQLYWKLKEGWITRNISLLLVDYSPKDSAKRVVTTDERL
RLGADEYIAIHGDGDESGEQISKLRERLNTCVDRQANKLKEAILHPDVFAVTWEQIPGRG
AFEMKQEELFDNVRIAAQKGKIHAVSITDNPGGNPALSAEILCSEIKRIGMEPLVHMALR
DKNRNEFESLLYGLAAMKVRNVLCLTGDYPATSGFNTMPKPVFDLDSVQGLQLISTMNQG
LEIESFGKKTLLAPTDFFAGAVISPFKLFESEQKCQYYKLKKKIEAGAKFVISQVGYEAR
KLHELIQWLKVNDYNIAALANIYVITYGLAKVMNAGQVPGCVVTDKMLALLDEERKAKDK
GLQARLDRAAKTYAIVKGMGYAGAHIGGYNITCEQVEHIIDNGEELSHNWQDYLPEFDFP
QKDSFYFFERDDKTGLNTDKLSPRKEKAARPPIYEFSRLAHATIFNPDSMGFKSFHPIAV
GIDRTHIPKHVFTDMEHLAKVVMFDCQNCGDCGLFDVAFLCPISQCPKNQRNGPCGGSQD
GWCEVYPNERQCIWVRAYERLKGHHKEDTIGEYIVPPNDWALQGTASWLNFYCGRDHTAK
RLGIKPPEPKNGPASTK
>A0A7C3G1A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSLRTALERGEFVISCEVGPLKGTDTTEILENAELLKGKVHAANVTDQQSAVMRLGSLAT
SYLIKEKGLEPIFQVTCRDRNRIALQSDLLSASALGIENVLALTGDFPSFGDHPQAKAVY
DLDSVQLLWVIDRLNNGYDMVGNELQGKTNLFPGAVVNPGADTPAALELQIMKLEKKIAA
GAKFIQTQAIYDVDAFANFMKRIEGYKVPVLAGVIPLKSVGMARFMNSSVAGVFVPDHLI
QRMTEAERKAETGIQIAAEIINGLRGICQGVHIMAIGWEKRVPQIIETAGL
>A0A6G8FRA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter coleopterorum|TrEMBL
MNATLLTGSAPTRARFSFEVFPARNGAAALALGHAVQHLSAADPDFISVTYGANGSNRDA
SLDLLKYLRNNTTALPLAHLTTVGESRGALRQTIHGIMDAGVHDFLALRGDPPRGASEND
PSVIGSPSSVELLEIISQVRADRPPLTSVGRTVVAAYPNGHPQSRSRSEDIDWLIAKQEA
GAQFAITQLFFRADDYLSFVAEARVAGLHIPVLPGLMPVSTSAQLRKVASLAGQPAPAEL
EHEMEAEGGFAPELGVEYAVSLARELLEGGAPSIHLYTFNRHEQVLAVLRELNLLTPSPV
G
>A0A7V3SC48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAKSLFEEKLSSGKFLVTTEVGPPKGTDISELVHHIDLLKDRVDAINVTDHQSSVMRYPS
LGGCLLVKERGGEPILQMTCRDRNRMALEADLLLADSRGIHNVLALTGDSVDIGDHPEVK
PVFDIESVQLIRMIRTLESGKDAAGNDLKGAPSFCIGASVHPGADFIEPQLIKFEKKIAA
GAQFFQTQGVFDLASLRRFMQYASQFNVKILAGIIVLASARMAKYMNENVPGIIVPKEVV
EELATAEKGKGLQKGIEIAVRLIRGIREERLCDGVHIMAVGNERIVPEIIERAIEERVPS
QGR
>A0A2E5Q434|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTETDDEIHQPGRNVAPGYSSTGRLEQILRAGHFAVTAELSPPDSADPAEVYRRAALFAG
HVDAINATDGSGANCHMSSVGVCSLLTRSGYSTVMQISCRDRNRIAIQGDVLGAAAMGVS
NILCLTGDGVQAGDQPDAKGVFDFDCMSLLKTVCCMRDESRFLSNRKLSSPPKVFVGAAA
NPYAPPLDYRPYRLKKKIEAGAQFVQTQYCFDVQRFRQFMTRVRDLGLHEHCFILAGVGP
LVSARAAGWIRKNVPGVCIPDNVISRLQGARDQRQEGIAICIELMQQIREIEGVCGLHIM
AYRQERSVGEIVQGSGVLDGRRPFDPHSVHPS
>A0A4Q6BY70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTDTNAEIAQIRALLANASIEMTCKDVDVLAEVATLLPPKTDIFIALFPNQTFDELTAAA
KAVNAAGLTAVPHVPARRIPDMAEVKRIAAGFAGAGVTKFLLIAGDMTAPAGEFDSTIGV
LESGEFAKAGIKEMYMAGHPEGHAHMTEQQLREYEAKKVAITNAQGVKLNFVTQVVFEPE
PMIEWEKTLRRNGITNPTRPGLPGPASIKTLLRYAKICGAGASIKALTSGKASLIASLLG
DSGPEESIRTLARAQAAGQTKFAGLHFFAFGGFLKTSKFVSAMQKGRISLSKDGEDFKVD
V
>A0A351JZZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAQSLREALSSGKLVITSEIGPPKGTNIARMLHHIDLLKDKVDALNVTDHQSSVMRFPSI
GGCLAIKERGGEPILQMTCRDRNRLALQAELLFAYTRGIRNILCLTGDAVPVGDHKEARG
VFDLDSSQLLHTIRLMESGKDLGGNDLDGVVEFCAGAIVTPEAKPIEPQLAKFEKKVEAG
AEFFQTQAIYDLENFSRFMEFARQFRVKVLAGIILLVSARMAKYMNENVPGVLVPQNLID
ELASAPKGEALSRGIEIAGRMITALKKNSICDGVHVMAIGREEVVPDILAAAGL
>W4A3A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus rhodochrous ATCC 21198|TrEMBL
MEFSPPRDADAEARLWRAVREFERLGPAFVSMTYGAGGSTRDRTVRVTGQLAQETTLLPV
AHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWTRHPEGLEYAEELVRLV
RDLGDFHVGVASFPEGHHRSPDLEHDTRYLVHKLRAGAEYSITQMFFDVEDYLRLRDRVV
AYDPEQGAKPIIPEIMPITSLRTARRSLELSGSRLPAALEERLVRAAGNGPEEDRAAVRE
VGIDVATEMAERLIAEGAPCLHFITLNFARATREVLARLGIAVPTAV
>A0A0G1KRW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Collierbacteria bacterium GW2011_GWA2_44_99|TrEMBL
MLEKSAERLTPPEYLKQWITEANYEVLPTEKALDLINIIPETNTISVTCRPTGIEETVHF
AEMLGPEKMKRVWPHLAARRIYSQDHFDEVSLRLINAGMEKAFIVGGDGDPSFEDFKKTE
DVLNGLLIRGILPKKIRIGGYPEGNPVMDMDPIEVLLQKQEFAEKAGVQMEIVTQMFFDA
DTLFNWLMEIRQRGVYLPVELGLLGKLKWNSFVKVLETIGIKDAMAFLKSKPKLAMSLAT
GMITGFSPRYLLTELAEKNTPELGINGISIFTLGNITNSVKCLTDIASENI
>A0A451D587|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MINIIQDNNDKYNYESYHLKNKIKISFEVFPPKDFASEQQLFNSIKLLNQCHPNFYSVTN
SIYSKNRDATFFIVEKIRYLTHKTVFAHFTTIGYDESDIKTIATNYWKNGIKHILALRGD
LPVRYTKKIIYASNLIKLLKSINNFKILVAAYPELHPESSNLQEDLNNLKHKIDLGAEKA
VTQFFFSVDKFLKFRDNCADMGLSVSLIPGILPIVNINQLKKFSDMTNVYIPQWIFDEFY
KCEDNFDKCTALSVNIAVNLILSLYKEGIKNFHLYTLNQSYLSLKICNQLGLF
>A0A3A0F5I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MRIADLYSSSTRPVVSFEFFPPKTDAGYRSLYATIADLKRLDPGFVSVTWGAGGSTRTKT
VDLVVQIQRELGIPAMAHMTCVGSPREELAATLDHLVREGLQNVLALRGDPPKDAAAFVP
VEGGFAHASELVAFIRARYPLCIGAACYPEKHPDAPSAEVDLARLVEKVQAGAEFLITQL
FFDAEDYFAFVARARAAGIAVPIVPGVMPVVSAANARRMAQLGGSRIPDALEAELARCGD
DDDATLEVGVAWAAAQCQALLAGGAPGLHFYTLNRSPAARRVYEALF
>K8GQJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbyaceae cyanobacterium JSC-12|TrEMBL
MPVSHSATSSFRTAAQSGEFLITAEVCPPKGGDPTHMLEMARLLKGRVHAVNITDGSRAV
LRMSSLASSVLLQQIGVEPICQVACRDRNVIGLQADLMGAQALGIRNVLALTGDPVKAGD
HPSARPVFELESVRLLQLIGKLNAGLDFNEKPLPDGATELFVGAAIDPQCGSWSGLQRRF
ERKLAAGAQFFQSQLISDFDRLEKFMAQLAADCKKPILAGIFLLKSAKNAQFINRNVPGV
QIPDYLIDRLERASDPLYEGMLIAAEQVRAARELCQGVHMMAVKREDLIPKILDLAGIAP
LQETTVNSLDGITPAIGS
>A0A520PGR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MEKLTTIPNSLESDIFMERADDLQKNIEHNIRWSMEILPQNIVNASFIPAFINEVYITMI
PGRAFRETIEAAEQIRLIGKQAVPHISARGFTGTGDLEKCLSGLQAAGIERALLIGGGHS
EPAGNINCVMDMLKTGLFAKYGINSFDFAGHPEGNPDDPNSEFNLLEKLSWAKEHRISAR
IVTQWCFDTEGTNAWISRLRQKGVKNPIHLGIPGPSTLKTLMRFAKVCGVSASTTVLRKY
GLKLSKLMFVNKPDKIISDLRGYDQLHLYPFGGIEKSSEWLHEWQQKD
>A0A2E7S7A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MNQEGHSLFIKDILKTSRTISCEFFPPREVEGINNILEVASRLKPYNLSFVSVTYGAGGS
TQAFSEEITLRLKRELNFEVMAHLTCVSQTQPEIDEVLKRLVSAGIENIIALRGDPPAGD
SNFVPVEGGFAHASDLIKHIDQKFSFGIAAACYPEGHTESIDLHSDIQYAKLKVDNGADF
LVTQLFYDNQDFYDFVERAEKAGITVPIIPGILPILSAPQIRRFTSMCGASIPSHLDTQL
DKHHDDDKTVRQIGIEHAINQVQDLWANGVQGIHFYVLNRSYSVSKILDSLQIADHTNLS
KTTT
>A0A523S8M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIRDIIEQRGNSLSFEFFPPKTQEAETQLFDAIKRLEIFRPSFVSVTYGAGGGTRKTTR
RVVEHIMLETSLTPMPHLTCIGQSEDELKAILRDYQQLGIENILALRGDPPRETAWSPAD
DGHCHATDLVRLARSFDGLSIGVAVYPEGHVEAPSLETDMFYTKQKIEAGADFAITQMFF
DNRFFYDFMERAEKAGIRIPVIAGIMPITDIGKMKQFCQTCGSTLPSSLVRRMETAGSPG
EVARIGIDFATRQCEDLWQHGVRFFHFYTLNRAEAVTEVLHNSSLEGLLGETSEEDLTSS
ILVT
>A0A3A0FQQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSEQILAERFTNPAKPLICLEVNPPRGTEVEPIIRRLENQLSGIDFLNVTDCALARMRLA
ALPFGALLKQRLGLEPLVNLSCRDRNLIAIQADLLAGWVLGVRSLVALTGDAVSVGDEPD
RKGVFEVNSLGLLGAISTLNAGKDLAGNDLKGRPEFVAGAVVNPNANNTAAELKRLRRKK
EAGAVYALSQPVFEEQSAREFFSAAKEVGLPILMGLMALKTARALDGIVKGPGIKVADSI
KKKVSESGDSHISRVSIEHCLKLAKANKQLVCGFHVISGTTPLLALELAQELTRS
>A0A3M0IUT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces shenzhenensis|TrEMBL
MNPLRSASPAVSTSLLEDFSLEMTGKDVPKLEEAAGLIPQGTRINVTFLGNEDVRMRLDA
ARAVKRLGFRPVPHISARRLGSQAEFEHFLAGLRADATGAEVFTVGGDPTRPEGPYADSL
SLIESGLLSEYGARHVGISGYPEGHPAIPGDVLWTALREKSAAIAAQGLDGSVITQFGFD
VDPVLAWIERVRGEGITLPVRIGVPGPAGVRRLMTYATRFGVGTSASIAKKYGLSLTNLM
GTAGPDKFLRALADGHDPAQHGEVKIHFYTFGGLKATSEWIAQFRKEALA
>L8LQ73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gloeocapsa sp. PCC 73106|TrEMBL
MSNYLRQAIERQEFLVTAEITPPKGINPSHMLAMARLLRGRVHGINITDGSRAVMRMSSL
AACVLLKQEGIEPICQIACRDRNSIALQADLLGAAALGINNILALTGDPVKAGDNQQARA
VFELESIRLLKLIKNLNQGLDINEQPLPDGVPDLFPGGAVDPQLKSWSSLQKRFEQKIEA
GSQFFQSQLITDFERLDKFMTQIASNHNKPVLAGIFLLKSAKNAQFINRYVPGVHIPDST
IERLSQAADPLLEGIKIAAEQIKIARSLCQGVHIMAVKREDLIPQILDLADVSLPG
>A0A4U1L2D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. L-1-4w-11|TrEMBL
MTLSLGQLEEARRALDAPLFADVAGDAHVSFEFFPPKTDRMEAAMWDAVQTLAPLGPRFA
SVTYGAGGTTRDRTHGTVARIARETSVPAAAHLTCVDASRDEVDAVAREYWAAGVRHVVA
LRGDPPTMSERFVPHPKGYANAADLVAGLKRLHPFEISVAAYPERHPDSANDDADLDNLK
RKLDAGASRALTQFFFEPETFFRFRDRAAAAGIGAEIVPGILPVSNFAQTRKFAGLCGAA
IPDWMGRLFEGLDDHPAARQLVAATIAAEMCRKLYAGGVRHFHFYTLNRAELSYAICHLL
GLRPQAGEARAAA
>A0A2A4Q4F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAKIPDLANNGSSSLKIICDFSPPRGGTPSLIGDLDGLNPDIVSVAYNPGKSVRVNPVAA
AAWIKANTKQDVVFTLATRDMNKVAIQSLLLGAQLLGLQNIVIVEGDGLSNRDRERFKAV
YDFQPTSLIESVRDMNQGKDFRGLKLRVATDFSVGATIDMGRPSDSEIQLAVRKAQTGAK
FFLAQAEFDPSVIARFRADFESHFDKGHAPPVFYGVQILAKDGIIFGNVPQRTRSELGSG
RSGEEIALELIQNLMDQGVRTLYLVPPIFRGGRRDYDSARRVIESARRLAS
>A0A518CYC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium Pla163|TrEMBL
MKIKELFAQKEPVFSFEFFPPKTDKAAEKLMETVAELKGALSPGYVSVTYGAGGSTRERT
LECVRRIHTELGLTAMAHLTCVGHTAVELTEIVRELVDAGVENVLALRGDPPQGETRFSA
VDGGFANASQLVEHLRGEFDLCLGGACYPERHPEAISLESDVRWLKHKVEQGVDFLVTQL
FFDNADYFAFVDRIRAAGIDVPVIPGIMPITNVAQIERFTSMCGARIPEELRVRLDPIRD
DAAAVMATGIEHATLQCRALIAAGAPGLHFYTLNKSHATRSILASVKAL
>A0A520P8C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MFEHSRIMEILTTISDSLESDRFMEPSDELQENIKQNTTWSMEILPHNIAEVSLIPEFIN
EIYITMIPGATCWETIEAAQQIQAVGKQAVPHIGARSFTGEEDLEECLSGLEAAGIERAL
LIGGGHSEPAGSISCVMDMLKTGLFAKYGINAFDFAGHPEGNPDDPNSAVHMLEKLRWAE
EQGASARIVTQWSLDTECTNAWISGLREKGVNNPIHLGIPGPSTLKTLMRFAKVCGVKAS
TTVLRKQGLNLSKLMFVNKPDKIIEELRGYDQLHLFPFGGIERSSAWLTEWQTKSYI
>A0A1C4XLE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora marina|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTQAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWIAHPEGVRYAEDLVRLVRDSGDFRVGVAAFPYKHPRSPDVDSDTAYFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAQRFERVADDPEAVRRLGVEQASEMCEKLLDEGVPGIHFITLNRSTATREVWQRLR
ASARV
>A0A5B1CTG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubripirellula obstinata|TrEMBL
MSLASHYTDGTCAISFELFPPKTPQGLQTLLDNVRKLTEFKPAYFTCTYGAGGSSQSTTL
DVLSKVRELTDLPVASHLTCVGSTVQQLEDYLNKATDCGTDYIVALRGDPPKGETEFQAV
QGGFRYANELVELIREKFSSLGIAVAGYPEVHQEAVDAKTDLDNLKRKVDAGADIIITQL
FYDNADYYRFRDDCVAAGINVPVVPGILPVTNFAQAQRIASMCKAGIPDSLRTAMTDSDD
ADHQFKIGVEHARMQTVDLVENGVPGIHYYVLNKSAAAESLLDGMQLGTA
>A0A348Z1U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp|TrEMBL
MHIKELFKEKEVVFSFEIFPPKLTSPIETVYNTLEGLQGLNPDYISITYGAGGSVNNNRT
CELSSLVKNKYGIEALAHLTCIGSTKSEINEILENLNENGIENILALRGDVPEGNPSIGE
FNNSQELINHIKETKEFGIAAACYPEGHIESRDIEREIEILKLKENAGAEYLISQLFFDN
KYFYKFLNSVEKSSVEVPIQAGIMPVTNRKQVERIVSLCGANLPSKFIKIINRYEHDKDA
LRDAGIAYALEQIVDLVSTGVRGIHLYTMNNPYIAKRITNSIGSILNSINKRQVI
>A0A178LR12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium iranicum|TrEMBL
MHFGPCGGVRPDGQCEMRAGPCVFPDVIPWVGPVPETRAVTAPLVLTDFTCDPFDLADMT
ATAEALAGACDAVLVGEHQNRPDFPPVLTASTLLDSGVQPWITLSCRDRNRVVLEQELRG
LALVGVKTVLCVTGDGRAYDVRPDVTQTFDLDGPRLVSLAASLAMTAAVPETPTAPPVSQ
RPQRLVHKQRAGAGLAVLNHVSVPAMVADFMAAARRAGLTIPVLAAVAVVTDEASAAVLQ
GLPGLGLDDAVVNSILTAPDPREAGIAAAVDEARALLSIDGVVGVNISGSASGAGTRIGA
EIKAEVGQRIRAWVHSDE
>A0A3D3YRJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MIRKIPDIFKEKKQTCSFELFAPKTEGGIEKLLETAAALRKMEPDWFSVTYGAAGSTRGP
TMEIVDSLQERFQVPAMHHLTCVGQRKAELKAMIEKMKARDICNVLAVRGDPPQGATYWE
TAPDGLAYSYQLVELIRSYGDFFSIGVAGFPEGHPNCPDKETDVRYLKIKIDAGAEFVIT
QLFLDNREYFEYMERIRRIGITVRIIPGILPITDYQALLRFCNICGVTIPQRVHDTFKPL
DGDARATYEAGVQFAVEQCQELLKGGALGLHFYTLNRAYPTGEILKQIKR
>A0A3C0Z251|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MACICEYVRDPQYGSASMAKVADHAMSNDGKLNIVCDFSPPRGGNPGLLDGAASLDPDFL
SIAYNPGRSVRINSVAVAAWVKANMGQDVIFTIATRDMNTIAIQSLLLGAQLLGLENVVV
VQGDPLTARDRERLTQVNDVRPAELIESIQGMNEGIDFRGLKLRQPTSFCVGATIDLSRG
LDAEAALTRRKVEAGAEFFLAQPTFDAKISQGLSDVYARDFGEELAAPVHHGVQIMSADG
VRFADIPKWVTHDLDSGRSGEDIALQVIRAYVDAGITHFYLIPPILRGGRRDYAAAARVM
ATARQAVP
>A0A7R6X0B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 113-3-3|TrEMBL
MSARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A857JJ06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraglaciecola mesophila|TrEMBL
MVSYAQGIDALNQSLSEVKGINVSFEFFPPKTETMEKTLWKSVERLAPLKPKYMSVTYGA
NSGERDRTHEIVKRIQSETGIAAAPHLTCVDASREELKQIAKDYWASGIRKIVALRGDLP
EGYTEHVSYASDLVALLRDVADFDIAVAAYPEKHPEAPNSQFDLLNLKRKAEAGANQAIS
QFFFDAEVFLRFRDRAAAAGIDMDIVPGILPVTNYQTLQRFAGFTNVHVPNWLHKMYDGI
HKDDQTTRNLMGASIAMDMVKVLAKEGIRDFHFYTLNRCELSYAICHMLGVRAD
>A5ZKB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides caccae ATCC 43185|TrEMBL
MKVIDLINNSKKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEEAPNIESDLYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAERVGIEWCVTQCKELMSHGAPSIHF
YSIGAVDSIKEVAKIIY
>Q8KTS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tremblaya princeps|TrEMBL
MRVTTEVVNVAGSSPVRCSLRVMPGLSFEFFAPRSHAGSIRLMCAQQVLSRFVPRFVSVT
RSTSLGQQAHIDTIASTLSVFPRTAPHVLFCQCPRALARELRAYELLGIRHLVLLRGDNG
IAPGSIGAPELVSMVRRSYGEAFYIDVAAYPDGHPMSSTIFEDVRALARKVRCGANSAIT
QCFYNPDAYYRLQDELQRLGVSLPVTPGIMPVLSHDYMSRFILPSGVDVPAWILKRLEAL
RYCSASVLEFGTDVALSLCESLAARGASDFHLYTMNDHRAVWRVCEHVLGSADACHRSGA
>R7AQT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis CAG:47|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A3N1MIX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. PhB93|TrEMBL
MTRARFEIIPSDGIGEKAERAFPDPAAVTLTVTSLPKHGTERTIDAAVELAGRGFRVVPH
LAARNVDGREALERALGRMGDAGIDEAFVISGDARSAAGSYSTSLELIRDARELRPELAV
DVAGYPEGHPHLSDESIAKHLRERAPYLRGIVTQMCFDVDAVVRYADRLRADGIDAELWA
GVPGPVERARLLSLGGRIGVGSSLGFLKRSSSVAGGLLRGRRFDPAAFVARLEAAAGDRL
AGLHVYTFNELDGLRAF
>A0A3R6TYG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM32-2|TrEMBL
MKIKDILAEGRPTLSFEVFPPKTADAYESVEKAASKIAQLKPDFMSVTYGAGGGTSDYTV
KIASTIKEEYGVTPLAHLTCVSSTREKVHHVLEELKAHKIENVLALRGDIPQDGKTPEVY
HYASELIHEIKEAGDFCIGAACYPEGHPESSNKSVDMDYLKEKVDAGCDFVTTQMFFDNS
LLYSYLYRIREKGITIPVIAGIMPVTSGSQLKRIAQMSGSYMPARFLSLVDKYGDNPAAM
KQAGIAYATDQIIDLLANGIKGIHVYTMNKPDVAAQIQSNISELLK
>A0A357X3A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp|TrEMBL
MIIKRTMHKLPDITTSPIIPASIEASPAQVLGPASLAGLFPQGVRVYLTDTGAASQGRLV
DAARHLRELGYNPVPHLAARRISSRSDFEEQVKRLAGEAGVSDVLAGGGGVDRPAGPFTS
SMDMLSTGIFDRCGIKHIAIAGHPEGSPDFSEETAMAALRLKRDFGERTGATMRIVTQFG
FDPARFIAWAEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESVVGPIERHWQANPSGPIRQIHVFPFGGLQNSADWLVGRGSWQSNEEKNAGR
SASPGSVAV
>A0A4V2V440|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Martelella mediterranea|TrEMBL
MTETPVFRGENRAFTFSFEFFPPKNADAEASLWHSIQALSVYEPEFVSVTYGAGASSRAP
TFAVVQRLLKETRLPTASHMTVVKSTREETNETIHQFRDAGVKRFVALRGDPPGGVGSAY
SPFPGGYENAADLVRGLKTIGDFDISVSAYPEKHPESADRAADIAMLKAKADNGADRALT
QFFFDNDVFEDYLNAVRRSGVSIPVLPGIMPIQNLRQLKNFAAMCGANIPAFVEKRFEGL
DDDAEGRFEVAADLAAEQIQGLLDRGINDLHFYTMNRSKLMIAVLERLGVQAPRPAAGAS
SATGVMQRA
>A0A176KTQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. FXJ1.172|TrEMBL
MKPVLAAAPVAGAALLDDFSLEMTGKDVSRLEEAQGSIPPGTRINITFLAGEDLGMRLAA
ARAVKRLGFVPVPHISARRLPSRAALEEFLSALAADGTAGNVFVVGGDPARPEGPYEDSL
AVLRTGLLQHHGVHHVGISGYPEGHPAIADATLWSALTDKAAAIGAECLGGDVITQFGFD
AGPVLTWLEAARARGMHLPVRIGVPGPAGVRRLLGYATRFGVATSASVARKYGFSLTNLM
GTTGPDRFLDTLARRYDPERHGTVKVHFYTFGGLRHTAEWIAAFRQQAGERAPAV
>A0A2G1NXM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon ex4572_44|TrEMBL
MDFKRKIETGKLVVTTEVAPPRGTDTTLLIEEADLLSGCVDALNVSDNQRSIMRMSPLGV
AHVLQEQGHEVILHTTCRDRNRLALQSDLLGAWNLGVRNILAMTGDHPLLGDTMGTKPVY
DLDSTQLLQAIQNLNRGHDIMNRRLDGGTGFMAGAVVRPDPNDKMQLLRLKRKVSCGARF
IQTQPVYNTEEFKEFIEKVSHLNTHIIAGILPIFSLKTVKFINDKLPGIIIPQEVVERIK
NSTDPAEEGIELAAETIKKLQDVAGGVHIMPIITHQHTEAILKRAGMLH
>A0A540VJV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litorilinea aerophila|TrEMBL
MLNPFLQKLMEQPLLGDGAMGTMLYARGASSEQCLEQLVVDRPGWVTGIHQAYASAGADV
ITTHTFGANRFRLAKHGLEDKVREFNFRAVRLVRDVREVTGRALFIAGNVGPLGRRLDLD
NPQERAEAEEAFKEQIGVLWEAGADLLLFETFSDVAELELAVQVARALCDLPIVAEMTFA
EDGLTPAGQSPELISQRLHAAGAHVIGVNCSVGPSHVLGTLAAMRQTVPDALLSAMPNAG
FPRRINGRLYYPSSPEYFAQQVPQLIQQGAQLIGGCCGTTPIHIRAMREALDAYLAGRNP
RPPAQLRGGDRPAPPEVDMGLAADLDTDRDDQPTLLLRKLRAGKFVISVEVDPPRAFTAE
KQIEGARYAKSVGADAVNVADSPMARVRMAALSLCAQIQQQVEIETIVHFTTRDRSLMGL
QADLIGAHALGIRNILALTGDPPNLGDNRESTPVYDVDSIGLVRIINAFNQGVDISGREM
GKRAQFTIAVACDPTRPNLSEEVDRFHQKVSGGAHFTMTQPIYDPQLWLNFLRLYEERYG
EFPVPVLIGVLPLQSHRHASFLHNEVPGITLSEEALERMRKAGANGRQEGVKMAQELLAQ
LKELPHVQGVYLMPSFGRYELACQVLEVLSPEERSGPLSPA
>F0SZ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobotulus glycolicus (strain DSM 8271 / FlGlyR)|TrEMBL
MKKGSHQTQVKTKQEQRNEVEMNIREYLKTNTLIFDGAMGTYYAQLEKKPLVKCEMANIH
DEEAILRIHHEYIRAGCMAIKTNTFGANVTCLDCPFEGVEEVIRKGYELARRAVAGSGVY
LFADIGPIPFRDNENLFAEYQKIADLFLDLGAVNFLFETFSSAEYLAQIAAYIKEKSPQA
FIITEFAVSPDGYTRQGNSGFQIFEELSGENSIDAIGFNCISGPYHLLQLAKKLEAKDKF
VSIMPNAGYPTVIDNRTFFENNAGYFADQMLEMAKEGIAILGGCCGTAPEFIRKTAAKIK
SLSLPEPAVKRIKITEGKPAAQAENPLMEKIRQGEKIIAVELDPPANTDIDFLMRSAQKL
QENKVDAITIADCPIARARVDSSLLACKLKKELGVTPIPHMTCRDRNINATKALLLGLNI
EGVNNVLVVTGDPIPSAQRDEVKARSNFNSAILANYIRTLNENTFARPFTIYGALNVNAR
NFEAQLKHARKKIENGVSVFLTQPILTKKALENLQEASRVLPAKILGGILPIVSYKNACF
MNNEISGIDVSPEIMDLYENASKEQARNLAVDISTRMVREISAYVDGYYLITPFQRLDIV
TDILENMLQSQAG
>A0A4R6VJP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora succinea|TrEMBL
MSESFTEALGRRVLLGDGAMGTLARASGGLVEGHGAELCVIAPELVSALHERYLAAGADV
LQTHTFAASRPRLERHGLARRVREINLAGARLAAAVRDAAGRPAWVAGSVSPATPPGLAV
PVEEARAAIAIREQVEALVEGGVDLVVLETFSRAAELLAAIRAVQDVTDLPVVAQATFVD
EDGELLTAAGESPADVVARLVDAGAVAVGTNCTLGPQGLLDVVRRMGPTGGPFLSAQPNA
GLPHVVADRSVRFAGDAEHFARYVLRYVEAGARLVGGCCGTTPEHTAAAARALTTHDAWS
PPATPRDARVVPAPRAVPDPTPAPDEEIDQPGPGRGAVERWLRGRPASREFLVAAEVAGA
GGPDEHLSRARRAVSGGASVLWVSRSRARRATTSTTGLAVHLHDRIDVDTALTVTSWQTS
LLALQADLLGLHALGVRTLVCETGNPPVHAEQAVGDGVWEVDGLELLRLAADLNRGVDAD
GAELGTATVFRLGARVTPGADDLDREAERAVAKVEAGAEFLVSRPVFELERLRTVLDALD
AAGRRVPVLASVGALTGYAQAEHLRHEVPDVVVPDAVVEPMRRAGDGPDAARTGLSLAAE
LVAEAAALVEGVVVRWPGSAVPGLDPATAVTRLRAAANGVDGSRVRR
>A0A8J3AJA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Galliscardovia ingluviei|TrEMBL
MFSLEIFPPKASSPVGTLYDTLDGLEGVKPSFISVTYGTGSDTDLLRTARITHTIKHEYG
IDSVAHLTALYASREQIDRTVDAYVEAGVSAVLALRGDERAGIEPTGQFQYASDLVSYIA
QRYPQLAIYGACYPEGHPQSISIQEDVDHLKFKVDSGVSHLISQLFFDNNDFYRFLERTQ
KAGINVPIHAGIMPIIQAQSAYRMTHICRSRIPARVQRLLDRWHDNPQALAQAGIVYASE
QIADLRAQGVEHIHLYTMNRPCIARKIWQNIHDFM
>A0A552C9F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis sp. Msp_OC_L_20101000_S702|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGSLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPVHN
>A0A2V4N2H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litorivita pollutaquae|TrEMBL
MTQTAKTKTPNISFEFFPPQNLEASFRLWDTARALAPLDPTFVSVTYGAGGTTRELTHDA
VATIHKNYGLNMAAHLTCVSATRDETLAIANSYADAGVTEIVALRGDPPKGSTGFEPHPG
GFNNSIELIEALAETGKFRLRVGAYPEKHPEARDTAADVEFLKRKIDAGAHSAITQFFFE
ADTFFRFRDACVKAGIDAPIIPGILPIENWKGTRNFARRCGTSVPQWLDDAFENAAAQGQ
EGLLSTAQCTELCSDLLEGGVEDLHFYTLNKPALTRDVCHALGVMPKASLENVA
>A0A2W6SMW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp|TrEMBL
MDTTTDGPDAFTEYWGTRSRECPKRMVFGPCGGVRDDATCEMDAHICPFAVLTEPIPWPQ
PLTSPASSSELINASRARPVVLSDLSVPAFDRGVLEQVASILGESSDAVLVGEHQNRPDY
PPTVMAQIIRGVGGCPWVTLTCRDRNRVVLEQELMGLGQAGADGVFCVTGDGRAQGVRQD
VTQVFDLDGTRLAALAAQADLAVGVPEAPEAVPTSIRPARLLEKQRAGAQLAVLNHVSTP
ESLRAFMSAARTQGVTMPVIAGVAVYTDERSAQVLAAFPGLHLDHSQITRVLAADDSVEA
GIETAVDEALALLDIPGVVGVNLSGLASAAGEVPAAKVKAEIGRRLRERLAVGHNR
>A0A0Q7TP11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudolabrys sp. Root1462|TrEMBL
MLMKTPPASVASRFSIEATRPKPAEIAAIAAAVPKGTEIYLPAVPTQSDDDLVLAAANVR
QAGLEPVVHIAARRVISVEALSRLLSRLHGEAQLRRLLVIGGDVDPVGPFADALAVIQKG
RLREAGIEQVGIGAYPEGHPQIPAERLAASLDEKIAAAVAQGLAVRLVSQFSFSPEAIVA
WLTQLRACGIEQPISVGMVGPTSVPALLRFAKRCGVATSLKGLMSGAATALIGNVGPDRI
IAALDAAQDAIGEVQPHYFTFGNLAATAEYAAKMAVKEIAAA
>A0A4R6VJQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora succinea|TrEMBL
MNDGSTTAAAAPREGCPKRMVFGPCGGVRHDGGCELDAALPCPWVDGDERVPPWPGPAVG
ARAGTLPDGMLARARESPVVLTDLSVPSFDLPALRTAAQIVAPVSDAVLSGDIHHQPTFP
PTFVAAELRAVGGHPWMTLTCRDRNRVVLEQELAGLAALGVEGVLCVTGDIRGPDVRPGV
TQVFDLDATRLAHLAASTGLAATVAITPSAPPREARVRVLAEKQRAGASLAVSNHVADPA
ELDDFLRAARRLGVDLPVLGAVAVFTDEPAADSLLAFPGLAMDPAKVAAVLDAPDPVAAG
IDAAVDEAEALLAVPGVVGVNLSGRASSAGHVEAAEIQAEIARRVRKVER
>A0A3S9Z384|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter spanius|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGATRQDLRDILQTYKSEGVRRVVALRGDLPSGMGGDAGELRYAKE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVAKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVNVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNQAEAPLAVWKELAL
>S4GQQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis JCP8522|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNAAGVFNHASDL
VSYIRSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A418YS17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium terrigena|TrEMBL
MSLPSIHPNWDLPPKGMTDGYSLEITAKDIDALREAAPAMAPETPVAVTFLPGESLEARI
EAARTVRALGFEPMPHFSARRLESGDDFETYLAAVVREAGVTRCFIIAGDPPEAAGPYTD
SMSLIRTGAFERAGIRAIGIGGHPEGHPNMTPDQCFDVLIAKCAEIEARGMAPLIVTQFS
FDAAPVLSWLAELRTRGINAPVRIGIPGPAGIKTLMRFAARCGVGASASVLTKYGISITK
LIGTAGPDKLVDALGKGLGSQHGKVRLHFYPFGGLTRTVEWINDYTTSR
>A0A7W9CR81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micrococcus sp. TA1|TrEMBL
MNATPATGRQTVMTEPSLEMTGKDKDIESLRDAASVIPQGTRINVTFLGNEDLSMRVKAS
TAARDLGFVPVPHISARRLTSQTELVEFLTALREQVGTTHAFAVGGDPSEPMGPYASSLE
VIESGLFKEHGFTDISIAGYPEGHPDITDAQLWDALERKNASLQEQGLNGTILTQFGFDV
DPIVHWIEEVRRRGIQLPIRVGVPGPAGIKRLLTYASRFGVSTSAGIAKKYGFSLTNLLG
TAGPDKLISALDAAMTEDHGDVKLHFYTFGGMRATAEWIEEYQRKH
>A0A7W6GA09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium metallidurans|TrEMBL
MALNQDARNRIGISFEFFPPKSEEAEGQLWKAVSELQDWNPDFVSVTYGAGGTTKAPTLA
TVSRFISSTPLATASHLTCVGATKEETHSVVESFRKAGVKHFVALRGDTPDGVGAPYTPH
PGGYANASELVAGLRELGDFEISVSAYPEKHPESRDVAADIDMLKRKADNGADRALTQFF
FDNDNFERYLEKVRAAGITIPVVPGIMPIMNLTQLKRFAGACGTVIPAFLDERFEGYDDK
PEERAKVAADVAAAQIEDLARRGISDFHLYTMNRSPLVSAVLTNLGFKRNAAQSAGAAA
>A0A812MA57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiodinium pilosum|TrEMBL
MHLTCTNQSSEMTENALKECKQLGVRNIVALRGDPPRGQEKWTATEGGFSSALDLVKFIR
KNFGDYFSVSVAGYPEGHPDNIETVEGGLAALTESEKRRARVVKDESGKEVVTVCRDANF
HKEMVYLKEKVDAGAAFVITQMFLDAQVFLEFVQECRKYDIKVPIVPGIMCLNGLGGLKR
MTELCKTRLPEGLLERAEKANTSDEAFKEFGIREGVAMCKALLEGGAPGLHFYTLNLEKV
VVGILKGLGKITDAQAAAFQAVEADAKFMVSAQGITTGAKSRPALPGNRPLAEVDPVMHD
LVQQEKARQTRCIELIASENFTSRAVMECLGSALTNKYSEGQPGARYYGGNEVIDKVENL
CKARALKAFSLDEKEWGVNVQPYSGSPANFAVYTALLPPHARVMGLDLPSGGHLTHGYYT
ARKKISATSIYFESLPYRVHPETGLIDFDELRKTALVFRPAMILCGASAYPRIIDFGKFR
EIADEVGAILMADIAHISGLVATGEHPSPFQHCDVVTTTTHKSLRGPRAGMIFFKYTEKI
PDIKDRIDMAVFPALQGGPHNHQIGALAAQLLEVDTPMFKDYARQVKANAKTLAETLMGK
GHKLASDGTDNHLLLWDLRPHGLTGSKVEKICEAASITLNRNAVHGDASALSPGGVRVGA
PAMTTRGCTEQDFRKIGDFLDRCCQIALKIQAEKGKKLKDFEAAIPGNAEVTALKKEVED
WASKFGYPGL
>A0A7Z0AUN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas moraviensis|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVTEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A1F9MLK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYD12_FULL_53_23|TrEMBL
MKSGSRLERILTSGEFAVTGELGPPKNGNAELVREKARLLKGSVDAVNITDCQTAIVRMS
SISAGLLTLAEGVEPVIQMTCRDRNRIGMQSDILGAAALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDAIQLLGMVKDMRDDKKFQCGEAIKSHEPRLFLGAAANPFAAPSEQFRAARLAK
KVANGADFVQTQIIYNVERFARFMQAVRDLGLHKKVHILAGVTPPRSVGMARYMQSSVPG
MDVTDEVIKRMQGAKDKEDEGINICVDIIRQVREIEGVAGVHIMAIEWESVVPEIVSRAG
LAARPVFADEPVALAAPVSAIEIRNTVAGGEESDAVLAVAKVEAEKIIAAARVEAAQYRA
SATTGGAGVVGQARVEIDEAGEDAMNEKERQMALESVRLGLDALKKAYGLSDDQFDALVK
FAGAEAILKREPLLATPVLAAATPVAPAAPAIDESVARKVAEIAAAEKAKKAEAAKKEAD
EKAAAEAKKVAAAAAEEAQKAEAAKKAAEAKAAEEVKKTAASEPQKVAPAVSASPTGAVD
AADLACEKTPLSERAAKVPEASYKQAYTGAIRQTVLGGEARGIKVGGATTLSFHLFEGSM
PNRPMIAFDVLDVKPDEWPDSLARHYQDVLDNPLAWAQKCVKEYGADAICLSMVSTDPNG
LNRPAGEAARAAAEVVKNIEVPVIVWGCGNGEKDTETLREITSLIGDKKVCLAPLSDSNY
RAIGATAMAFHYPMVAASPIDVNLAKQLNILLENLGVSLDSVLIDPSIGALGYGIEYTYS
VMERIRLAALTQKDEKLQVPFVCNLGREVWKAKECRLPSDALIGDQETRGILMEAITASC
MLMAGGELMIMRHPRAVALTKSLINGLMG
>A0A418YYJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium terrigena|TrEMBL
MTATERTLVYATSRPSLLNGYSLEMTIKECAALDAVAADLVPGTSVAIAFLPGEALESRI
AVAGYVRSLGLEPKVHLPARRIQSEAQLARLLEALAETADLKQVLVIAGDADVPIGPFAD
ALSVIQTGLLEASGIDRVSIGGHPEGHPAMDQHGCDDWLARKIDAIVLRGMAPDIVTQFG
FDADAMLDWLHRLRGMGISVPVALGVPGPTSARKLIAFAARCGVGASTSVLRKYGLSLTA
LMRTSGPDRMVDRLSSGLSADAGGRVTLHFYPFGGLDKTADWINARQP
>A0A5C4KV34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas jessenii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A1X2GT35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hesseltinella vesiculosa|TrEMBL
MKVIDKINLAEQEGRKFWSFEYFPPKTAQGVQNLYDRMERMQRMGPLFIDVTWGAGGSSA
DLTTEIVSTAQSVYGLETMMHLTCTNMPVEKIDTALKMAKECGCQNILALRGDPPKGQSN
WESCDNGFEHAIDLVKYIREKYGDYFCIGVAGHPEGHADCPDKEQDLQYLKEKVDAGADL
IVTQLFFDVNCFLNFVKRARAIGITCPILPGVFPIQNYSGLKRVITFSNNYVPQYIWDDL
EPIKDDDAAVKEYGIKLTMDFVHKFWEAGINGVHLYTFNLERSSRLILERLDLVASLEDV
KPLPWNPSLTQKRAKENVRPIFWKNRTKSYIQRTEFWDEFPNGRWGDSRSPAFGELDGYG
VSLKYTTDQSREMWGSPQTVDDVAVVFAKYCKGKINGIPWSAQPLEAETETIRQRLAGIN
LLGYLSINSQPAVNGVKSSHPTYGWGPKNGYVYQKAYLEFFVSPEKLDDLIDKIGKDPSM
TYYAVNKQGDLRANTQSDHPNAVTWGVFPGKEVIQPTIVESTAFMAWKDEAFELWNEWAR
VYDRQSKSAEVILDIANNWFLMNVVSNDFQDDAAIWRLFDLEIDGEISKKIRANVVHEGD
Y
>A0A258RNH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium 28-55-16|TrEMBL
MILPLAQMQEAGRAVASPLFAGLAGDCEISFEFFPPKTEKMEEQLWDSVVTLAPLGPRFV
SVTYGAGGTTRERTHKTVARIARETDIPAAAHLTCVEASKAEIADVANAYWEAGVRHIVA
LRGDAPNSDGKFVPHPDGYASAAELVEGLRKLHPFEISVSAYPETHPEALSAASDIDFLK
RKLDSGASRAITQFFFEPETFFRFRDAVAAAGVDAEIVPGIMPVSNFAAITRMSHMTGTA
IPDWMAHLFDGLDDHPSARQLVAATVSAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GKRPAAIVREVAA
>D6V3W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afipia sp. 1NLS2|TrEMBL
MSDTPPSAHTQAARPSISFEFFPPKTEEMEQNLWGVINRLAPLSPNFVSVTYGAGGSTRE
RTHSTIKRILEETSLTPAAHLTCVDATCADIDDVVDRYHEVGVRHIVALRGDPSGGIGTA
YRAHPNGYQNSADLVASIKRRHPDMEVTVSAYPEKHPESATIDADIDVLKAKVDAGADRA
ITQFFFDNDLYFRYLDRVRAAGITIPIVPGILPVQNFKLAKNFATRAGATVPDWLAEKFE
GLDDDAETRKLVAATVAAGQVQKLAKHGVENFHFYTMNRADLVFAISHLLGIRPNGSQQA
A
>A0A2A4U8J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxellaceae bacterium|TrEMBL
MTAAQNSKNNSASKNSKQFSFEFFPPKTPKGEENLRKVHAELSKKNPSFFSVTYGAGGST
RDGTLNTVLEMNAKGICTAPHLSFGNDNEDTVLELINQYKAAGVTRIVALRGDTPAQSDA
SQQSISANQLVEFIRKKTGDHFQLEVAAYPEIHPKSESFETDLQSLKAKFESGANSAITQ
YFYNPDAYFYYLDRCQQLGIDKPIYPGIMPIINFTNLARFSKACGAEIPRWISKQLEAYG
DDLQSVQSFGLEVVSQLCYDLLKGGAPGLHFYTMNKAEPTTLLWDDLQLSEM
>A0A4Q6EIX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxellaceae bacterium|TrEMBL
MTTPISFEFFPPKTDVGAEKLLKVHTQLQQLNPQYFSVTYGAGGSTRDRTLSTIDAIHGQ
GAPVAPHLSCIGDDRARIAELLDLYKAKGINRLVALRGDLPSGQVGLGELPYATDLVRFI
RRHSGDHFHIEVAAYPEMHPQAASFDQDIQRFAEKIQAGANAAITQFFFNADSYFYFVER
LQKLGIDTPIIPGIMPIINASNLIRFADSSGAEIPRWIRKQLATYGDDSASIKAFGHEVV
IKLCERLINAGVPSLHLYTMNQTEPTQQLVKDLGLA
>A0A5E5NZA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea apista|TrEMBL
MSGSLENKTIMTKPSFSFEFFPPKTADGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQRG
TLDTVIEIQREGVEAAPHLSCVGSTKENIRDILKTYRDNGIRHIVALRGDMPSGMGEIGE
FRYASELVEFIRAETGDWFHIEVAAYPEYHPQAKSPRLDLEHFANKVKAGADAAITQYFF
NADAYFRFVEDVQRLGVTVPIVPGIMPITNYSQMMRFSEMCGAEVPRWVAKRLEGFGDDR
EAIRAFGLDVVTALCERLLAGGAPGLHFYTLNAASATKAMWQRLGL
>W0E4P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfitobacterium metallireducens DSM 15288|TrEMBL
MENRFKESLLDKKTMSVTWELVPGRGAREKAQESALLAAEQAAKGGKVHALTITDNPGGN
PAMLADYLGEEILKLGIEPLVHFTCKDKNRNQMESQLYALDRAGVRNLLVMTGDYTESGF
QGRPKPVFDLDPTHGVELIGEMNHGLEYPGMKGIIRHQPSDFFAGAAVSPFKATEAEQMV
QYFKMKKKIASGAEFIVTQLGYDARKFHEVLQFIKLNDLNIPIIGNIYILPYGAARIMNQ
NKLPGCVVTDKLLAELDQEKKAEDKGLSARLLRAAKMYAIMKGMGFAGVHIGGNNVKYEQ
VEYIINKGEELSSKWMDLIREFDYPIPGGFYYYEKDEKTGLNTTIPVDRKNLPLNAPVGA
SFRALRLMHSLIFTPNQAFFPIMRSIYKARKNPRKHSLEHVIKVISNDCKDCGDCALLDM
AYLCPMSQCPKNQRNGACGGSFQGWCEVYPNEKQCVYVRAYSRLKKVGEEHQLDSYHIPP
ANWDLYQTSSWSNFYLGRDHSAAILGIPTPEEEVAKSQPQAEKKDVAK
>A0A4N2RLW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIILDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A6I4VS53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shimazuella alba|TrEMBL
MKVPIRDYIKNHVLLGDGAMATYLFQQGVPVRTCQEELNLNEPTLIESVHREYVKAGSKM
IETNTYGANRERLTRYGLENKVAKINREAVTIAKTASQDDAYVFGSIGSILAGRVMEYDP
EEYMDLFEEQATALLYGGVDGILLETFLDLHELKIAVQAVRNLTDIPLFAQFSLLEVGRT
RDAYSLSEAFKELEGKVDGVGLNCRLGPVETLRSLEKCIVPNSLLLSAFPNAGRLGITDG
EVKHKSRPSYFAETAELILEQGVSMIGGCCGTAPAHIAQIREIVKKYKPNKRKNPAIDEL
ASNRNRKLSIHEQKKDSILTKVQHQRTIICEFDTPKDLDTSEFLLGSRKLHEAGVDSITM
ADNALATTRMSNLALGAILKSQLGLNPLLHVACRDRNLIGQQSHLMGLHALGIDQILVIT
GDPSRIGDLPGASSIYDVTSFELIRMVKQLNQGISFSGKRLNQSANFVVGTALNPHVRKI
EKAVERLEKKIEAGADFVMTQPLYDHKSIHRLYEATRHIEIPIFVGIMPITSYRNALFLH
NEIPGIKITDDVLTLMSNTSNPQVARKLGIDITKDLLDCAMEKFNGIYLITPFTFWQMSV
ELTHYIRQKDQRLEKALL
>A0A6G9H408|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces liangshanensis|TrEMBL
MAFGTPSTRTDHAPTVRDLLAAGETTYSFEFWAPKTEKGERNLWNALRRVEGVAPSFVSV
TYGAGGSTRSGTVKATERIAADTTLTPVAHLTAVGQSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVKHPQGVRYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDTDIRHFVD
KCRAGADYAITQMFFEPDGYLHLRDRVESAGCTTPIIPEIMPVTSVKMLERLPQLSTAAV
PAALKERILAVKDDPAAVRSIGIEFATEFCAGLLAEGVPGLHFITLNNSTATLEIYENLG
LREQS
>A0A7G1JPX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVQSVLHSLNEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINKNQALRLLKTCENIRLPRKFKAIFEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A2S7V5J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio splendidus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPPGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A6B2WGV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID13588|TrEMBL
MSTLREILASGTRSFSFEFFPPKTDAGERSLWESIRRIEAVAPTFVSVTYGAGGSSRSRT
IAVTQRIAAQTSLRPVAHLTAVGHSVGELRRIIGQYADAGVRDVLVLRGDPPGDPRGAWV
PHPDGLNHARELVTLVKGSGNFSIGVAAFPERHPRSPDWETEVRHFVAKARAGADYAITQ
MFFRAEDYFRLRDRVAAAGCDLPIIPEIMPATDVRQIRRFAELSNATFPDDLAAQLAAAE
HDPDVAHRIGVDHATRLAQRLLDAGAPGLHYITLNRSTAALDIHRNIRSADAVPHRR
>A0A495S0Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. AG790|TrEMBL
MSAVTPTPATAASRIAGCPKSMAYGPCGGVNADGTCEVHPTPCVFLTRDLPVRWASPATE
ETPSDAVSEDPSRPATPAGRELVEIAARRPLVFTGFPVRALRADAVGPTAEALAGSVDAV
LSGDAGRSRVQFPPSYRAALIGATGLRVWMGFNARDRNRTALERELLSLRALGVAGVHCV
TGDHTQTGDRPDARPVFDLESTTTLPRAAALGLLTSFAESPAAPPVAERGARVAEKQRAG
GRMCLTQYAGDAEEVAAFVALCRAAGADVPVLAGVPLVVDREGAELLASFHAAKLPSGFI
DRLFAARDVRAEGIRLAVAYGRELLATGAVGGVVIAGGARPGGEAAYAADLATVARELGG
GS
>A0A142WTD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomyces sp. SH-PL14|TrEMBL
MLMPRIYEGSKFGLSIEIFPPKTEQGDELLYKALDRLRAYRPGFVSCTYGAGGTTSKRTV
EICRNIQEQMRLTATAHFTCVGSTRQELVDWLTYARENGIQNIMALRGDPPQGQTSFQAV
EGGLRNANELVTLIRSTFPDTGIGVAGYPERHPESPDADSDLRYLKAKVDAGADAVFTQL
FYVNEHFLRFRDRCAAAGLTVPVVPGIMPITEFARMKRITSLCGSEFPGSLASRLEAVQT
DAEAQFEIGVEHAIQQCQELRAEGVPGIHFYVLNKSQACERILESLGFQPEAAEFQLA
>A0A2M7HEZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium CG12_big_fil_rev_8_21_14_0_65_65_10|TrEMBL
MDEARTALDSPLFSGLPGDLDVSFEFFPPKTEKMAETLRASVDTLAPLGPRFISVTYGAG
GSTRERTHDEVVRIQNQAGIPAAAHLTCVDATREEVDAVARHYWESGIRHIVALRGDPSD
GSGIYTPHPGGYANAIELIGGLKQVADFEISVAAYPEVHPDSPDSQADLDNLKAKFDAGA
TRAITQFFFDPQCFFAFRDRAAAAGIEGEIVPGVMPVMSFAAVQRMSDLCGTAIPDWMEG
LFEGLDDRPDARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHMLGMRPKEQ
VDG
>A0A365VNH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MWU12-2534b|TrEMBL
FEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEIRSEGQAAAP
HLSCIGSTRENIAAILNEYRGNGIRHLVALRGDIPSGMVAAGEFRYANELVEFIRAEHGD
HFHIEVAAYPEFHPQARSAEDDRANCVRKVRAGADS
>A0A6J4LNF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Nocardioidaceae bacterium|TrEMBL
MPAGPPLRSPADRVIRELLSGGERSFSFEFFPPKDDRGAEQLWRALRELEPLQPTFVSVT
YGAGGSTRDRTVDITHRIARETTMVPMAHLTCVGHTRDELRSVVGAYAAAGIRNVLALRG
DPPDGPGTPWTPAPDGLSYASDLVSLVHSLGDFSVGVAAFPEGHREAASLEEDVRILRGK
QDAGAEFAITDMFFRAADYFALLDRARAGGVEIPVLPGIMPITSLGQVRRMAELSGREVP
AEVVARVSRHEGDPEAVRAAGIEVASELCHQLLDGGAPGLHFYTLNRSTATRQIYANLSL
PVG
>N8QB93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bohemicus ANC 3994|TrEMBL
MSQLSTCFTQNQFCVLVEYLCSMKEILPVKTQFAGFPALMTLADRVHADDDLAPIIAAQA
YPKHVEKVLHFAGKGRDISDFEQFLNDAQAIGQQNLLLLTGDKLKNHHKGEDSSERTRYL
ESVNAVMAAKQHGDFCVGVAFNPFKYAEAERDAQYLKLHKKLKVGADYIITQLGYDLSAL
KEAKAFLTQHGYSQKLLACVMPLTLGRANFMVKHQVAGIVITPHMLKSLGEEKESGLTDR
VYLRCALQILICKQLGFAGVHLSACHKPEEQLLLESYIEEYRHLGLDELELLWNALWQVK
TGKEFYPALTYYSRPVSSMQILKYQHLNLMHDALFESKVAKGIGHFIFQSRFWNGSLAAQ
ALLKTEFVSKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVDQTQILKNNLIPTVPIEVRGSSSWKNWYVNQAS
>A0A7K5ZRA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Onychorhynchus coronatus|TrEMBL
MVNETQQSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQATGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWSEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGHRVTCMPWNDDPLATETNLLKDHLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>D5V5D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter nitrofigilis (strain ATCC 33309 / DSM 7299 / CCUG 15893 / LMG 7604 / NCTC 12251 / CI)|TrEMBL
MLTDKIRNKESGILLYGITPPKIKHTEEEIKVIAQKHIERISKLPIDGLVLYDIQDESDR
TDEKRPFPFIKTLDPCEYSRTYLNDLVIPRVVYRAVGNYDEKSFPIWLELTKENQVHSVF
VGAASREQKKPMTLKEAYRLKKEVNDNLCMGGIAIPERHMVKHDEHLRVFSKIDNSCEYF
ITQCVYNLEASKIFLTDYAKYAKENKKEVVPIIFTLTPCGSAKTLDFMKWLGISIPNYLE
EDLKASGNILHDSMKLCVDIFRELYTFGRDRGIPIGCNVESVAIRKEEIEASIELLHEVK
KIMEEN
>A0A6C2DTP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudanabaena sp. UWO310|TrEMBL
MIESPQSVFEKPEPTFNKFRKAIANKEFLITAEVSPPKGSDPTHMLAQTRSLKGRVHAVN
ITDSSRAVMSMSPVAASVLIQQQLGIETICQLACRDRNRIALQGDLFGAAALGITNILAL
TGDPVKAGDYPDARSVFDYESVRLLQLIQKLNQGLDANGKALPNQGTDFLAGAAVDPQSP
SWSGLQKRFERKINAGAQFFQSQLITDFERLDKFVNQIANQSDKPILAGIFLIKSAKNAI
FLNKFVPGVQIPDRIIDRLAKAKSPLQEGMAIAAEQIQTARQICQGVHIMAIKAEHLIPE
ILDRAGIALL
>A0A316C1A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcaceae bacterium R-25|TrEMBL
MKVSQVYKKKRSLSFEIFPPKKDAELDNIDETLEVLAELEPDFISVTFGAGGSSNCNRTI
ELAKKIKYDYKIEPVVHLTCLHYDREEIDEFARVLKGEGIENILALRGDPNPNVPAKNDF
RHSSDLISYLKGSDDFCFLGACYPECHPESSGVVSEIKSLKKKVDAGAEVLLSQLFFDNE
IFYRFHEECKIADIDVPVIPGVMPVINAAQIKRMVSLCHASFPARFQKIISRYEDNKEAL
FDAGMSYCLSQIIDLLVSDISGIHLYTMNNPLVARRICEGIKNIV
>R5Y951|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerotruncus sp. CAG:528|TrEMBL
MKIADILKNNRVTVSFEVFPPKEWSKIENTKAVIAEMAKSKPAFMSVTYGAAGTRTGFTT
EIAQAIKENGITPLSHLTCLTSTKDKIDDVLNEWKATGIENILALRGDIPDGFEFPSDQH
FHHASELVSEIKSNGDFCVGAACYPEIHPESANRVEDINHLKEKVDCGVDFLTTQMFFDN
DVFLRFKENCLIKGINVPIIAGIMPITNANQIKRSVELSGCAFPKKFQKIVERFGDNPAA
MKQAGIVYATEQIIDLMANGQNNIHIYTMNKPDVAGAIAAGLSEIIYG
>A0A5C0ZVI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olivibacter sp. LS-1|TrEMBL
MKITDHISNAKNKTLISFELLPPIKGQSIQGIFNTIDPLMEFNPPFIDVTYLREDYIYKQ
HPNGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARKSESSFVPTPGGHAYASDLLQHVVNMNNGQYLHDYMDNTEKTDFCIGVAGY
PEKHFEAPNLETDFQYLKQKVDLGANFIVTQMFFDVNKYKAFVDKCRANDINIPIIPGLK
PLTTSKQLTSLPKVFHLDIPLELSKAVQACKSEKEVKDVGIEWMIQQCKDLIKMGAPVLH
FYTMGNPEPTKRIIQGVF
>F3FKL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. japonica str. M301072|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSTEDLRKLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VKFIREETGSHFHIEVAAYPEMHPQARNFEDDLQHFVNKANAGADSAITQYFFNADSYFT
FVERAEKLGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLQLPR
>A0A085FZD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buttiauxella agrestis ATCC 33320|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATREELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNYKQAHKFATMTNVRVPHWMAQMFE
GLDNDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A1F9RY87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium GWA2_69_24|TrEMBL
MAKRRAVKPTPEFGSEAEEERDRDDPAAQVAAGVEYAIRQYRGLIGSGVPGLHIYLFNKA
EATRRILATLNLPRYPHASGALIFTARSAWSRRISVRSETVWHCPLA
>A0A1E3VX87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloceanibacter methanicus|TrEMBL
MEVSFEFFPPKNQAMEETLWHAIRRLEPLRPKYVSVTYGAGGSTRERTHATVARILSETT
LVPAAHLTCVNATTAEVDDIIRDYWDLGVRNLVALRGDPPEGVGERYVPTPGGYENAAAL
VAGIKKIAPFVTSVACYPEKHPESPSVEADIAMLKAKVDAGADGAITQFFFDNEVYFRYL
DRVRAAGINIPIIPGLIPINNFKQAASFAKKSGATVPDWLERRFEGLEDDPETRHLVAAA
VAAEQVLGLVDQGITSFHFYTLNRADLVYAICHLLGLRPAKAFAEKAVSPGATLEPVPVQ
SAKVAS
>A0A6J4MVW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Nocardioidaceae bacterium|TrEMBL
AQHPSLCDASRRPGQGGPVRGAADTHDRGQGPRARAGGPCADRDRVPGEGARRHDGAGRA
VDQARVLRGPAPGVPHGAGPRAAGRDRRPADDRRHPLGLRPGRGQDPAGGGVRLGPADAG
RPHRAGTTLRGRGHHRLPRDAPVDRRRRDGPVDVGQAPARDLDRQQPRLRPRGHRQVAAA
HAGTGDHPAPVAGHARARRARQAAGDGDEDRRGRLHPVPRQAQGGDAPPRGAGRLHRRAV
PRAVRAGAGQARRGGRRAARVHVQPGGRDRAVASGVPRPARAAHQAAL
>A0A7W0HM99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosalsimonas propionicica|TrEMBL
MSAKTPSKLEKVMAAGHLGVTSECGPPRGSDPEVIKHKAELLKDCVDAINVTDNQTSVVR
TSSLATCIHLKLMGLEPILQMVTRDRNRIALQSDILGAASFDIANVLCLSGDHQSFGDNP
QGQNVHDLDSMQLLWTVRKMRDEGTFLGGDEIKRPPKMFVGAAANPFADPFEIRVPRLAK
KIEAGAEFIQTQCIYNLEKFEEWIRLAEDRGLTEKCYIMAGVTPFKSAGMAKYMKNRVPG
MDVPDDVVKRMADTPKGSQAEEGINICVETIQRLKELKGVSGFHIMAIEWEEKVPEIVER
AGLMPRPETD
>A0A7X9BNW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MTRSNLQRVLQEGHFAVTAEIGPPRSCNTEFVRRKGSLVQGYADAFNVTDNQTAIARMSS
IAAAAILQQEGLEPVVQMTCRDRNRIGLQSDILGAAALGLTNILCLTGDHQSFGNHPEAK
NVFDLDSIQLIHTARMMRDEGRFICGDEIKVRPQLFIGCVANPFADPFPFRVVRLKKKIE
AGAQFVQTQCVLEMDRFRRFMEMVCAEGLHEKTAILAGVMPIKSARMARYMQKNVAGMMV
SDQLCERLEKAEDVPKEAINIVVEQINQIREIPGVRGIHIMAVAWEEMVPEIVRRAGLYP
RP
>A0A7C9JLK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldimicrobium sp|TrEMBL
MDRFQRDLKEKDFIFTFELVPGRSIRTQQFSAILKFIEKAPEYEYFSAFSITDNAGGHPA
LSPVALGRVIKSLGLSAIIHLTCKDKNRNQLESELLALDRENLHNLLVLTGDYPFYGYLG
RAKPVFDLDSVLLLRLITEMEKGVEIPKGAPGGGNRLPPIPFFKGCAVSPFKLTIEELWW
QYLKLYRKLKAGARFIITQVGFSPFTLYQLKLILNDGLTKYFSERLNDESFHKPEEDSQF
KKVPILPSILYLQEPSIKALLRGRVPGILLGRRVWKRFKEVGFSEEMALEVCAKLTVIYQ
RMGFKGVHLCGFPPNWDLLKRFFELYHRISQEIINKEETYYELLTEFDDYIVYEDNGELI
EKNLANIDKPLPKKSFSFSYSINNFFHKLFFSRKSPLYSTLLKFFTWITKKRSVEKFFST
LEYAIKRPLFYCQECGDCTLWDFNYICPQSQCAKYILNGACGGSINSFCEVYPYKKVCLY
VRVLRQGDPKETIKRYLAKDPPYLPPRDWSLYRTSSWINFYLKRGHFKHEN
>A0A7W1SZG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriales bacterium|TrEMBL
MAADFPSRLKQSPVLCDGAMGTLLYAKGIFINRCYDELNLSAPDLIRGVHQDYLHAGAEV
IETNTFGGNYYRLARHSLTDKIRDINLAGAQLAREAAKSFDAWVAGSVGPLGIRIEPLGK
TSFEEAREAFRQQIAALVEGGVDLLILETFGSLEELHQAMLAVRDIDPRIPMVAQVTIDE
DGICLDGSTPEIFAPRLEHWGADVIGCNCSVGPVAMLDAIERARAVTSLPLAAQPNAGIP
RSVEGRNIYLCSPEYMASYARKFAAADVRLIGGCCGTTPEHIKCMKSALRVGEARGKVAV
TTVAAADAPALPVSPVVPLAERSHLGARLKAGDFVTMVEIVPPKGTDVTKELEGARFLKS
VGVDAINVPDSPRASARMSNQALSLLIQQQVGTEAILHYTCRDRNVLCIQSDLLGAAATG
VRNLLCITGDPPKMGNYPDATAVFDVDSIGLVNIVRNLNRGMDIGGNSMGTPTAFVVGVG
ANPGVPNLDEEVQRFQYKVEAGAEYAVTQPVFDLKLLETFLKKIESCRIPLIAGIWPLVS
LRNAEFMQNELRVSIPDEIFDRMARAQSPAAAREEGIAIAREMLLAVAEMVQGAQISAPQ
GRYSSAVDVLEVLGTYRRAAIQ
>A0A3A6P7N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurivibrio sp|TrEMBL
MKSGSRLERILTSGGFAVTGELGPPKSGDPEVVRKKAAILRGHVDAVNITDCQTAIVRMS
SIAAGLIAQQEGVEPVIQMTCRDRNRIGMQSDILGAAALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMVRGMRDEKKFQCGEAIKSAEPRLFLGCAANPFANPFEFRAPRLAKK
VASGADFVQTQIIYNVEKFARFMEMARDLGLPEKVYILAGVTPPKSLGMARYMKSSVPGM
DVTDEVINRMKDAADKQEEGINICVDIINRVREIKGVSGVHIMAIEWEEAVPEIVKRAKL
EPRPVFAEDERQPVQAKEVIEVVAPAVQPAAAPPALDTDKLLAEARAEAEKIIAGARAEV
EKMRAAAVLQTTAGSAPEYEDAGEHEMNEKERQMALQSVQMGLNALKKAFNLSDEQFEAL
ASFASAEAVLKRQPPETASAGSVIAPVAAEMVKPAPDKAAEEANKAAEARDAAEAKKAAE
AKAAEEARKAAEGKAADEARKAAAAKAAEEARKAAEAKAAEEAQKVAEAKKTADAKAAEE
AKAAEETKKAAEAKVAVAPKAVAPAGDLAVAALAVEKTPFAERAKKIPAASYQVKYTGQI
KETLLGSGDKAIKVGGESSMPFHLFEGAMPNKPLIAMDVLDVQPEEWPDSLARHFSGVLD
NPLAWARKCVDDYQAEALCLSLVSTDPNGMNRSAAEAAKVAAEVINNINVPIIIWGCGNA
DKDTETLREITSLTGDKKVCLAPLSDSNYRSLGATAMAFQYPMVAASPIDVNLAKQLNIL
LENLGVSLNSVMMDPSVGALGYGIEYTYSVMERIRLAALTQQDEKLQVPIICNLGREVWK
AKECRLPSDAVLGDQERRGVMMEAITATCMLLSGGEVLIMRHPKAINLTKSLINSLIS
>A0A3D1K723|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaeria bacterium|TrEMBL
MPESKTTTQMEIDFQKQKSGNVFRDRLNKGSFYVLIEAATPEKKEDFAIAAQRLKAVEAS
LGKYDTLGTGLAITDKTHGSNTWNIADFANELSKDDRDCHVLYISGRNATANDIVDTVAR
CRSSGFQNVVPVTGDAYFPEGYRKKHKLNFVDSVCTLNTLKSGGDKDFFFAGCTANPFKY
TPADLFPQYYKMVKKIKQGAEFIVTQSGWDMMKLQELRWYLEMRELHFPSIARFTLLTTE
LFEEIFAGKRPGIHISAELRKILLNEAKYGYAQFASAQWRRLQIYAAGAKFLGYTGIQIS
GVERQEHIATACSKVAEAMREFKSFEDWRDGYLSYLSRADMTPYPYRHFMFNNLFTKAYP
ELATMKKVDLPECGKYEKLHYRMCKLLFSKAHRHSSNEHLLSKKIFTGCRKCSSCRLPFT
QFVCPETCPKGLANGPCGGTRADGTCEFGGKQCIHAKIFRRASWLKDLDSLEERYIKPVE
KI
>A0A7J0E4V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinidia rufa|TrEMBL
MKVIEKIREVVGTENGGGADKRMERMVAHNPSFCDITWGAGGSTADLTLEIANRMQNMVC
VETMMHLTCTNMPVDKIDHALQSIRSNGIQNVLALRGDPPHGQDKFVQVQGGFACALDLV
KHIRSKYGDYFGITVAGYPEAHPDVIQSVGVATPEAYQNDLAYLKRKVDAGADLIVTQLF
YDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKIPSEITAALEPIKDN
EEAVRAYGIHLGTEMCKKIMASGIKTLHLYTLNMEKSALAILMNLGLIEEAKISRPLPWR
RPTNVFRVKEDVRPIFWANRPKSYISRTIGWEQYPRGRWGDSRNASYGGLTDYQFMRPRT
RGKKLHEEWAVPLKSVEDIYERFLKYCLGKLKNSPWSELDGLQPETKIINEQLGNINSKG
FLTINSQPAVNGAKSDSPSVGWGGPGGYVYQKAYVEFFCSRLKLDDLVNKCKDFPNLTFM
AVNKEGNWVSNTTLHEVNAVTWGVFPAKEIIQPTVVDPASFMVWKDEAFEIWSRAWAQLY
PEGDPSRKLLEEVQSSYFLVSLVDNDYVNGDLFAVFKD
>A0A7W0C9E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosalsimonas propionicica|TrEMBL
MPSAFKKALDSGKFVVTSEVAPSKGTNLEKMAHHVELLKDKVDAMNVTDHQSSVMRFPSL
GGALLVKEKGGEPILQMTCRDRNRLALQADLMFAASRGINNVLCLTGDSVMLGDHKQAKA
VFDLDSSQLVAAVRTMERGKDMAGNDLDGGVRFCAGAIVTPEANPIEPQLIKFEKKIEAG
AEFIQTQAVYDIDNFKKFMDYARQFDVKILAGVILLTSAGMARFMNKNVAGVMVPQNLID
EMAAAPKGGALKKGIEITGRMIAQIKDEKICDGVHIMAIGKEEVVPDIMSAAGLL
>A0A6P0MI55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symploca sp. SIO2C1|TrEMBL
MTKSTHNRFRTAAQSGEFLITAEIAPPKGGNPAHMVKMAQALKGRVHAVNITDGSRAVMR
MSPLAASVILLQHGIEPVCQIACRDRNRIGIQGDLLGAQALGIHNILALTGDPVKAGDYP
DAKGVFDVESVRLLKIIANLNQGLDANDKPLTDGATDLFAGAAVDPQLKSWSGLQSRFER
KIEAGAQFFQSQLITDFERLEKFMDKIAAGTDKPILAGIFLLKSAKNAQFINKYVPGVNI
PQTIIEQLAAAANPLEEGMKIAAEQVKIAAQICHGVHLMAVKREDLIPQILDLSGILPLD
KAN
>A4X9V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)|TrEMBL
MALGLPSILPNPQSAIGELIRDRRPTFSFEFMPPKTAQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAAAGVRNVLAVR
GDPPGDPTGEWIPHPDGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDIDSDTAYFVR
KCRAGAEFAVTQMFFDADEYLRLRDRVVAAGCDTPIIPGVMPVTKISTIERSEQLSGAPF
PPALAARFERVADDPEAVRQLGVEQASEMCQRLLDEGVPGIHFITFNRSTATREIWRNLR
VSNPA
>A0A6C1B8N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrogeniibacter mangrovi|TrEMBL
MTQTTHFSIEFFPPQTDAGVEKLRATRAQLAQLRPDFFSVTYGAGGSTQERTFDTVFEIQ
HEGLEAAPHLSCIGSTRESIRAILKRYQDKGIRRIVALRGDLPSGVVDPGELRYANELVE
FIRAETGNWFTIEVAAYPEYHPQARSPQSDLAAFKRKVDAGADSAITQYFYNVDAYLHFR
DECEALGIAVPIVPGIMPIVSFSKLARFSDACGAEIPRWMRRKFESFGDDTDSVKAFGLD
VVTDLAARLIEEGAPGLHFYCMNQAGPTSTIVERLGLS
>Q9CP31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella multocida (strain Pm70)|TrEMBL
MSYAKEIDTLNQHIADLNGKINVSFEFFPPKNEKMESILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLEAAPHLTGIDATPEELIEIAKDYWNSGIRRIVALRGDEP
KGYAKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLVKMAAITNVKIPAWLAKNYEGL
DDDPTTRNLVAASVAMDMVRVLSREGVNDFHFYTLNRSELTYAICHTLGIRPSIE
>A0A1Q9VGC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora sp. CUA-673|TrEMBL
MAPLLARPRYEVLPLAGVLEQTGLLPEDTVVTVTASPRRGTGATVELCEKLAAQRLRPVP
HLAARQLTSRGELADVLDRLAGSGVDDVFVVGGDAAVAAGPYPDGLALLRAMAELDRLPA
AVGVPSYPEDHPSIDPETLWASLLSKQDYATYTVTQLCFDVGAVAAFLTAAQQRGLRLPV
VAGVPGDVDAVTLARVGARIGVGDSLRFVTSNRSTVLGLLKAGLRTPRSGRHAVLRGLAE
LDPGLPLAGLHFYTFNRVRATARLVTDLAAGPAGGAHDRPAGGEG
>A0A1A5NX77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. H-KF8|TrEMBL
MALGTASVRTDHARTVRDMLAAGKTMYSFEFSAPRTPKGQRNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVHETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPTADWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSAEWDTDVAHFVD
KCRAGADYAITQMFFHPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPRLSNASF
PDALKERILAAADDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A1I3DQ51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tindallia magadiensis|TrEMBL
MLKEKIINRKSGILLYGLTPPKNNQPEDKLFEISKRQIDRIEKMDIDGLVLYDIQDEQER
CLEERPFPYMKTVDPEKYSDTYLKALRMPKIIYKCVGKHSVEDLEKWVNNDSEETRISVF
VGAATGNQSVSIHLPEAYEMASAKGTNFLLGGVAIPERHISKKNEHSRVINKEDKGCRFF
VSQAVYNIEASKNFLSDYYYRCLEEEKNMSPMIFTLTPCGSVKTLKFMKWLGVSIPGWME
NELIHSQDTLNQSLQLSKNVFEELLEFAAKKKIPIGCNVESVSIKKEEIDASIALLKDVR
KLMG
>A0A366XYT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus taeanensis|TrEMBL
MSLLDKLRHSILVGDGAIGTLLYSYGIDQCFEHLNLTHEKEIYNIHKSYIEAGANVIQTN
TYGANSIKLARYGLEDEVVQINKKAAQIAKAAAEDRAFVVGTIGGIRGIQKNAYSITEIE
QAFKQQLLALLGEEPDGILLETYYDLEELKAVLKIVKNETTIPVIAQVSLHDPSVLQSGI
SLKEALQQLADAGADVVGVNCRLGPTHMIQALEEVPLSDGVYLSAYPNASLPDIVDGQFT
YNSDPNYFEQAAVHLKEQGVRLIGGCCGTTPEHIKAIIRGLKDRQPVLKKDIKKKSHRFD
IVKKERTEKPLHEIVRERPSVIVELDPPKQLNIDKFIEGTKALHHAGVDAVTMADNSLAT
PRISNMAMSVRIKEASKARPLVHITCRDRNLIGLQSHLLGLHTLGINEVLAVTGDPTKLG
GFPGATSVYDLSSYDLIQFIKQLNEGVSFSGKSLGEKTSFSVAAAFNPNVRHVDRAVKRL
EKKIECGADYFMSQPLFSEEKIIETYEATKHLSTPIYIGIMPLTGTRNAEFLHHEVPGIT
LTDETRRRMAVCDGDPTKTREESIAIAKPLIDTALKYFNGIYLITPFMRYDLTVELTNYI
HEKTKHSKVNQVVQ
>X1P576|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
LDKQVHILAGVIPIKSAGMARYMRDYVSGVSIPDEIVTRMEEAKTAKEEGVRIVLEIIEQ
LKEIPGVHGIHIMAVGWEDIVPEIVEKAGLLPRPVL
>A0A6L8TGM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia massiliensis|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVQLLESCVD
>X0ZEG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MIKEGHKYASELVEQIKLLNEGVYILSSVEKDYKVSPTNFGIAVAGYPNGHPECPDKKKD
LEHLKIKVDNGADYIVTQLFFDIDVFLEFVENAKRIGIDIPIVPGVMPMDKYGPIKFVSK
QMGIEIPEKLKDKLEAHKDDKDTIKKILEEHTLLMCKKLVEQVL
>X1GL78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MIKDYVDAINITDNQTSVTRLCSLAACIRLKLMGVEPVLQMVTRDRNRIALQSDILGAAS
FDIFNILCLSGDHQSFGDNPQGQNVFDIDSIQLIQTIRHMRDEGKFLGGDDIDRPPKMFV
GAAANPFADPFEIRVPRLAKKVAAGVEFIQTQCIYNLDKFELWMKQVRDRGLHEKVHILA
GVTPFKSAGMAKYMKNRVPG
>X0Z711|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKLIERFEQGKFVITCEVGPPKGIEVEKAIDELEPLRSKVDAFNVTDLQSSVLRAGSLAT
CRLLKEKGFEPICQLTCRDRNRLGLQSDVLSAAALGIENLLCLTGDHPALGDHPEAMPVF
DLDSVQLLSAVKGLMNGKDMAGNDLEGRPPQFTLGAA
>A0A0F9Y9Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MDIVDTDARFSFEFFPPRTDVGVEKLKVVHDELTALKPDFFSVTYGAGGSTKDGTRQTVT
RIKQAGSDVAPHLSFGGSSREEIEALLKSYQAMGINRLVALRGDIPSGTGTASQYYYANE
LIEFVRKTTGDHFHIEVACYPEIHPQSDSYDTDIDFFKRKIDAGANSAITQYFYNQDAYF
YFLDSCAKAGIDIPIVPGIMPITNFTNLQRFSNSCGAEIPRWIRQRLQAYGDDSASIREF
GIEMIQSLCEDLLAGGAPGLHFYSMNQTEPVRQIWQQLNLR
>A0A1Q7SQB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium 13_1_20CM_4_70_14|TrEMBL
MPSAFSQRLDAGPLLCDGAMGTMLYARGVSLDACFDVLNLNNPRLVQAIHAEYVAAGADL
IETNTFGANRFKLAAHGLESQVREVNRLGVRLARDVRESTGRDVLIIGSVGPLGKYLAPL
GSVTAEDARAAFREQAEGLLEGGVDACIVETFSDLAEIALAIEAIRSVTDLPIVAQMAFT
DEGVTFTGRSPAEVGRTLRALGVQALGANCSVGSSTLYGVLEQMVPAAGSLPLAIQPNAG
LPSRVGERLIYLSSPAYMAEYAARMVEAGARIVGGCCGTTPQHIAAMREALDRQRPPRRD
AVRPTITVTAPVLRESAGLLTRRPATTLQRKLEAREFVVTVALDPPRGHTVEKLVQGAKV
LKERGVEIVDINDGSLGRVRMAVLPTALLVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALDVRNILALKGDPPRAGDYVSTTAVFDVNATGLIEVLKRMNQGLDATGNSIGLPTSFCV
GAALNPGAENIKAEISRFHRKVHAGAQWLQTQPVYDLAELDRFLEQAGGPPVPVIVGVLP
LHSYRHAEFLHNEVPGITVPEQIRARLRDAGDGALRVGIEMAQRLVREIRSRYAGVYLMP
SFGRFEVVAEVLDALH
>X0ZDL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKVVNLYKGNKPVFSLEVFPPRNGESLEAVLNTIDSLWSFKPAFVSVTGGALGSMRGGTI
AIAAGIKRKYGVEGIPHFTCVNKSKHDIENLKEI
>A0A0F9VDG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MTSPAVSFEVFPPKSVDASFRLWDTAQALAPLAPRFFSVTYGAGGSTRDLTHDSAHVLRR
TSGLPVAAHLTCVGASKAETLEVANSFAEIGVTDIVALRGDPENGAATFTPHADGFADSV
ELIEALANTGKFTLRVGAYPEPHPESPDQAQNVEWLKRKFDAGADEAITQFFFETETFLR
FRDACAAAGITKPITPGIMPVTNWKSARNFATRCGASVPAALDEAYAAAIRDDRHDLLST
ALCTEMCSELVSEGVENLHFYTLNRPELTRAVCRALGVTAQTSLSDVA
>A0A3M6WKM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MHRRRGKGLSRARASAESKVGLAAFVDEKAKATIRHSLLPSFGTGNVNLSHCCGTRNMDK
LTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGSTSAK
SLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGVRNILALRGDPPRSDEYND
PNNPLSEQDDSNRDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEHDLP
SLVEKTAAGADFIMTQLFFDVEAYNDYEKRLRSHESGLFRTIPIIPGLMPVQSYQILRRT
TKLSHASLPPDVLSRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTLNLE
KVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSSNRN
SMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPINSRANTLAISEGQGSAGREATWDDF
PNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLQGEIEAMPW
SEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSNDPIYGWGPKNGFVFQKPFVEL
FLPSADWQRLKPILQSDDQVTYYAGNAAGDFQSSDENSVNPVTWGTFAGKEIITPTIIEG
DSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDALIA
A
>A0A3M7J274|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMSYDAEIFIEWAKKVRAAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAELFVKYMSGKVETLPWSEQPISPESNVL
TNDLVNLNSRGLLTINSQPAVDGMKSSHPVYGWGPNNGYVYQKAYLEVLISPSLITELIR
RMDANADITYYAVNNSGELKTNAPQDGGPNAVTWGVFPGKEIVQPTIVETISFLAWRDEF
YHLGSEWAKCYDEGSQSKNLIKEITESWYLVNIVDNDFRNERGIFPLFDGLKVQGVEPTA
AAVNGVAPLVNGDAQHGDVEKKQGAQKPEVNGVPDKNNAVNHADGSAVNGHVKN
>A0A4R1KZ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lonepinella koalarum|TrEMBL
MSYAKEIDTLNQHIADLDGKINISFEFFPPKTEKMEETLWTSIHRLKTLKPKFVSVTYGA
NSGERDRTHSIVKSIKQQTGLEAAPHLTGIDATPEQLRQIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVTLLRDVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVESYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMSSVTNVKIPTWLAKMYDSL
DEDQTTRNLVASSVAIDMVRVLSREGVNDFHFYTLNRSELTYAICHTLGVRPEFR
>G5II50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi WAL-18680|TrEMBL
MKIKDILGQGKPTLSFEVFPPKTEDKYESVEKAAVESAGLSPAFMSVTYGAGGGTSRYTV
DIASMLSNTYQVPALAHLTCVSSTKSQVHQVLEELKERNLENVLALRGDIPKDGVVETDY
RYASQLIYEIKQTGDFCVGAACYPEGHVESVNKTADIGYLKEKVEAGCDFVTTQMFFDNN
ILYNYLYRIRERGITVPVVAGIMPVTNVAQIKRICQMSGTYLPARFKAILDRFGDNPAAM
KQAGIAYATEQIIDLIANGVNGIHVYSMNKPDVAKRIMDSLSEIL
>A0A0R1FK02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei DSM 12361 = ATCC 700308|TrEMBL
MPLQYSFEITPNINQNNLDGLLKLNPEFISITDRNHDMDNLLQSIRIADYIHANSSVDVV
IHLTGIDKDEKGVQEMLDLMQQHDIDSVLALRGDKLSQNDTAVTFPHADRLVEFIKQQYP
HVNIVGTCYLNSSDEEMKWLRQKVEKGCTKLISQFSFDVNDYVEYLNQIQIDTPIWLGIM
PVISKSQAQRMLNLTHSTAPDELNALMNQHEDEFGEYGVQYTAGMIDQIKQAGANHIHLY
SLNNASNTKKIINKI
>A0A3M7F305|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMSYDAEIFIEWSKKVRAAGVPERVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAQLFVKYMSGKVETLPWSEQPISPESNVL
TNDLVNLNSRGLLTINSQPAVDGMKSSHPVYGWGPNNGYVYQKAYLEVLIPPSLIAELIR
RMDVNPDITYYAVNNSGELKTNAPQDGGPNAVTWGVFPGKEIV
>A0A098UCN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. JS1662|TrEMBL
METPNISIEFFPPKTPEGADKLRVARQKLAELNPKYFSVTFGAGGSTQHGTLSTVLEILA
EGHDAAPHLSCVGGTRESIRAILQEFKEKGIRRLVALRGDLPSGYGGAGELRYASDLVEF
IRQETGDWFHIEVAAYPEMHPQAKSPQDDLQAFARKVQAGANAAITQYFYNPDAYFQFVD
NARKLGVDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWIRLKLASFGDDSASIKAFGLDV
VSGLCEKLLAGGAPGLHFYSMNQAAATTAIWQRITAA
>A0A3D2FC95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp|TrEMBL
GGSDQHLTHDAAETLHRTSGHRVAAHLTCVGASKDDVMNTANKFADAGITDIVALRGDPS
KGDTEFRPHADGFEDSCALITALAKTDRFNIRVGAYPDVHPDAASSKQNIDWLKAKIDAG
ACEALTQFFFEADGFLRFRDACADAGITAPITPGILPITNWNSARKFAQKCGTYIPDELA
QTFDKATRDGRLDLLSVAQCTELCDDLLNEGVSDLHFYTLNRPDLTRDVCHALGVTQSHS
IRNVA
>A0A853QLP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGIHIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>Q18JC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)|TrEMBL
MALGAQSAVDQDGVSNLLRGARFELMPFDSFNDELESLPAGSSIAITTSPQLGIEQTVER
AEEAAAQGYEVVPHIAARYVEDEAQLASIAERLSDAGVNDVFIPGGDREEPAGEFTSAYD
LLEVLDELPYSFEDIGITGYPEGHDFIEDEELAMAMDQKAPHATYIVTQLCYDPETILEW
VESTRERGVDLPIEIGIPGVMNYQKLLQISQKVGVGDSIRFLRKTTGVFEFVRQLIGSRG
VYEPDDLINGLSPYVEDEYYNIRGVHIYTFNQTPDLESWRQTRLA
>A0A7K3KLI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eggerthellaceae bacterium|TrEMBL
MKAAGITTVLALRGDPIKKPAAGTPSANASGTDSKSTAGTSASHTGATNAAAGGTTEAAA
HEIGASNDAPGTGTVAGALGNASNSTVGAPEFVHATDLIPLLKDAGFCVGAAAYPEGHID
CLDLQADIEHLKRKQDAGADFFITQLFFDNDDFYRFRERARAAGITRPITCGVMPFLGKS
QIERMVFLCGSSLPSPIIKLLARYEDDPVALRQAGIDYACKQLVDLGRNRVDGVHVYSMN
HPDIALAAAQALAEAGLRD
>A0A0C5RQS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida S13.1.2|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMQAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLGQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLTAGADFLTLQLGF
DAAKHQEAMHWMGRQPTPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHEIKQLLALEARIEHWQTQIHTLEQWAPA
WQASWQMPGLPAVIFHPPQAAWRQGELRVDASFKEKARYHLLHGMHSLLFSRRNGLSKAF
GWAVRRPLWATRVGAQVLHTVERAVKRPLVGCDTCGRCRLEDTLYVCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLNERLIPCIDVETRHRSSWPLWFQAATP
RRLSPQPAPRSQPES
>A0A5U8IFX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella newport|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRNSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKSEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6P2B6J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MDKIPFRQRLNAGTPILADGAIGTLLHQRGAAINACFDALNLTAPDIVVQIHRDYIIAGA
RLLETNTFGANRIRLKEYGLSGRVAEINRRAVDHAQTAITAAALDEPVYIAGAIGPLSSR
LRHYGHITETDMRETFAEQIRALILAGVDALILETFTDHAEILTALHVAQDVRAELARDV
PIIAQMTFAADNRTVLGHAPARVAHDLSRAGADVIGVNCGVGPSQIATVLQQMNAAVPDA
GLCAMPNAGFPEAIGGRVMYPATADYFGDYAVTFKAAGAAIIGGCCGTTPEHIAAMHAAL
SDPLRSVPIIPMNGDDQPPEPQAPPHPTELAMRLAEGRFTVTVEVAPPRSFTLDDLVGKA
HLLRAAGADLLDVADTPAARMRMSAYAVAHVLQSQVGMETVLHFPTRGRNILRVQGDLLA
AHALDLRNLFVTMGDPTRIGDYPDANDGYDIVPSKLIDLITHKMNEGQDMGGNSIGRPTA
FTVGCALNMFADDLDRELGVLEKKLSAGADFALGQAVFEPHKIELFLQRYEERFGHAFNL
PVLMGIMPLYGLRQARFLHNEVPGISIPPEIMKRLEDAGDDAPQEGVRIAQEILKAIQGL
VAGAYIIPAFGRYELAAEVIDAVTMAR
>A0A3N1AX55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. Llam0|TrEMBL
MALGLPSVLPGSQPSIGELIRAGQPTFSFEFFPPKTPAGERLLWQAIRELEPLRPSFVSI
TYGAGGTTRDTTVDVTERIATETTLLPMAHLTAVDHSVAELRNVIGRLAGAGVRNVLAVR
GDPPGDPTGEWVAHPQGVRYAEDLVRLVRESGDFSVGVAAFPYKHPRSPDIATDTRYFIR
KCRAGADFAITQMVFDADDYLRLRDRVAAAGCDTPILPGVMPVTKLATIERSEQLSGAPF
PPALAAQFARVADDAEAVRRLGIDQANQLCQRLIDEGVPGLHFITMNRSTATREVWLNVA
AGARA
>A0A348PEQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHIRDVLARDGMTASFEFFPPRTDAAWNEFVASLPEFEALQPSFVSVTYGAGGSTRDRTD
ALVTRLATDTTLAPVPHLTCVGHSTAEINQILQAYASRGVSNILALRGDAPRAQTAESAD
FRHAIDLVRAVKSFNESRCHPDQRGFGIGVAGFPEGHSETPNTLVQMDHLKAKVDAGADF
IITQLFFDNNAFFDWKARCSLAGITVPVIAGLMPVTTLAGLKRMAELAAGTRFPAPLLRA
IKRCEDDAESVANVGIHWATEQARDLIDRGVDGIHFYTLNRSDATRRIYRTLGLAGRVGS
AATGNQIR
>A0A1G3Z4B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium GWC2_42_7|TrEMBL
MKTIHSKFGGGRPLLSAEFYPPKTEEGARQLMTAAHALKSFDLDFVSITYGAGGSTRGLT
CEYADLLANVFGFTVLPHLTCISHSKKEIESILEGLDSRGMKNIMSLRGDFPKGQTATER
GPFQYASDLVRFIKGKYPEMCLGVGGYPETHPQAISIEKDIEYLRGKVAAGADFITTQLF
FDNRYFFEFVTRCRSIGITVPIIAGIMIPCSLPQIESFSQLSKATIPQKLKESLSAASSE
SEALEVGTRWASTQINELLSHHVDGIHLYTLNRSAPAISILREIRRVG
>A0A353RS90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
SLEIFPPKKDSSYNTIYNTLLRLRGIPADFISVTYGAGGSQAQRDKTIEIASLILTTYHI
EPVAHLTCVGLDRAEVIDTLERLKANQVQNIMVLRGDITPSMTPKEDFKHASDLAAFIKQ
YDSRFNLLGACYPEGHYQAESLEQDIENLKIKIDSGVDHLVT
>A0A1T5GN92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. 49Tsu3.1M3|TrEMBL
MFPIRLEIIPSEGIVEKIQSAVPLTTTLTITCLPHHGTGRTMRTAAQLSSLGYTVVPHIA
ARSLADRAQLAGIIRECGGSGISEVFAVGGDAPQPAGPFVNGGELLREIADISGGQMAVG
VAGYPEGHPGIGPLQLLESLLAKQELASNVVTQMCFSAESIHSYTAMLRREGVTLPVLAG
VAGAVQRTRLITLATKIGVGTSLRFLSGKRPLALRLLSGERYSPGTLINELTAQPVVDGI
HLYSFNCFDELPGSVAASSTELSATTSQGNTHV
>G7Z9J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum lipoferum (strain 4B)|TrEMBL
MTAPTSAQPSISFEFFPPKSEKMEQSLWQSIRRLAPLSPDFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGRYEP
YPGGYAYAADLVAGMKRIADFEISVAAYPEAHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDVYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPAKLAETFEGLDD
DPETRQLVAATVAAEQCQELQARGVHDFHFYTLNRSDLTIAICRMLGVKAKAAAAVAPVA
G
>A0A1J5LET4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MedPE-SWcel|TrEMBL
MTTPEISFEFFPPKNLEASFRLWDTVQSLAPLAPRFVSVTYGAGGTTRELTRDAVTTLHK
NSGLKVAAHLTCVAATRQETLAIADQYAEAGITDIVALRGDPPKDQGQFAPSADGFSSSV
ELIEALADKGRFNLRVGAYPESHPDAASPQANVDWLKRKLDAGADEALTQFFFETETFFR
FRDTCARAGIDTDRITPGILPIENWKGVRRFAQSCGTAIPAWLEEAFDKAERDDRTDLLA
TALCSELCTELLEGGVKRLHFYTLNRPELTRDVCHALGVKSKIRLENVA
>A0A2V4PAA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces tateyamensis|TrEMBL
MALGVPSTRPDRAQTVRELLAAGKRSYSFEFMPPRTEAAEHKLWDAIRRLEGLNPNFVCM
TYGAGGSTRGRTVNMVGRIAAETTLTPVAHLTAVDHSVAELRNIIGQYADQGVRNVLAVR
GDPPGDPLGEWVTHPQGVTYAYQLVELIKGIGDFCVGVAASPNMHPRSTDWDQDIRHFVA
KIRAGADYAITQMFFEVEDYLRLRDRVEAAGCEVPIIPEIMPVTNAKQLVRFPQLSGAPF
PADLERRLRAVVDDPQALREIGMEHATSMSERLLAEGAPGLHFITLNGSTATLQIYQNLG
LHRG
>A0A5B8AVN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Georgenia wutianyii|TrEMBL
MQSGRESWLVDAAATPRSTGAGASARSDGRVSLSTASLLTVPRGRPTVSFELYPPRTPAA
AAAAWETVERLAAAAPDFFSVTYGASGSARDASRQLVQRILAETSVTPIAHLTCVDSTRE
ELRQLVRELVDDGVRDFLALRGDPPDGRPATRPGGLSRSSQLVALIRDVERERLGGRGLS
IAVAAYPAGTSHTRAQDVAALLEKQEAGADYAITQVFYDPAAYADLVAEARAAGVHLPVV
AGIIPLTEPRRLTRLAALTGVPVPDDVLDLLAAAPDDEERHRVGVAATVRLAEGVIAAGA
PGLHVFTFNQYRPALDVVERLRRPLAHTRPITRTTR
>A0A0K2RLX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Hiyo8|TrEMBL
MFPTRIEIIPSAGIVEKVQAAVPLSTTLTVTCLPHHGIARTMEASIKLSLLGYTVIPHLS
ARGLEHRAQLSGILRDCEAVGIREVFAIGGDGPQGSGPYRSSLPLLADIAEYTGGSITAG
IAGYPEGHPSVSGLDLLDALLAKQHLATHVVTQMCFSAPTILDYAALLRREGVELPVWAG
VAGPFPGPNCWPWQPRSASGRP
>A0A1I3J486|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas sp. Nm34|TrEMBL
MKSQKVFSPTFSFELFPPQTPEGVEKLRAARHQLAQFKPKFFSVTFGAGGSTRDRTFDTV
LEMLADGHSVAPHLSCIGSTRENIYSILRKYQESGIRHIVALRGDLPSGMAQPGEFRYAN
ELVTFIRKEFGNTFEMDVAAYPEYHPQARSAQEDFRNFRNKIEAGADSAITQFFYNADAY
FHFVDMCEAANLNVPIVPGIMPINKFSQLVRFADNCGAEIPRWIRKKLEGYGDDIASIHA
FGLDVVTALCERLLKAGAPGLHFYTLNSAVLTTKIWQRLGL
>A0A350QPB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHMSDVIKRDTTTFSFEFFPPSTEKSWNQLEETISQLTRLGPSFVSVTYGAGGSTRTKTH
DLVKRLKETSSLDPVPHLTCVEHDPEQIQEILSAYAETGISNILALRGDVPAGSVQGDHF
GHFPHAADLIKTISAFNRSGAHPDPRGFSIGAAGFPEGHPETPNRLVQMDHLKNKVDQGV
DWICSQMFFDNRTFLDWQERCRLKGIDVPIFAGIMPVTSLSGLKRMAELAAGTNFPARLL
KALERAGPDPKNIERVGIHWATQQCLQLMDEGVQGIHFYTLNKSKATIEIYKSLGVTDSE
QLRGR
>A0A109JCY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium altiplani|TrEMBL
MALNSDARRKIGISFEFFPPKSEEMEGQLWNTVSELQDWNPDFVSVTYGAGGTTKAPTLA
TVSRFLSETPLATASHLTCVGATKDETHSVIDSFRKVGVKHFVALRGDAPGGVGAPYQPH
PGGYANAAALVAGLREIGDFEISVSAYPEKHPESCDTAADIDMLKQKADNGATRALTQFF
FDNDNFERYLEKVRAAGIKIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGYDDK
PEERAKVAAEVAAEQIEDLARRGLTDFHLYTMNRAPLVSAVLTNLGFTREGARKAGAAA
>A0A0T5NRG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius atlanticus|TrEMBL
MSTPTVSFEFFPPKSLEASFRLWDTVQTLAPLDPSFVSVTYGAGGTTRELTRDAVATLHK
SSGLNVAAHLTCVEATREETLAIAQDFADAGVNEIVALRGDPPKGADGFTPHPEGFADSC
ELISALADMNRFKIRVGAYPEVHPEAADAQANIDYLKRKIDAGASEAITQFFFDTEAFFR
FRDACAAAGIDAPITPGILPIENWAGTKRFANACGTKIPAWLDEAFTKAARDDRETLLAT
ALATELCSELIEGGCEHLHFYTLNRPELTRDVCHALGITPKVALRDVA
>A0A0D6PD83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidocella aminolytica 101 = DSM 11237|TrEMBL
MRDNEVQVSFEFFPPKTEKMEADLWQAVTALAPCAPRFVSVTYGAGGTTRERTHKAVARI
ANETALNAAAHLTCVGASQTEVLKIAEAYWAAGVRHIVALRGDPPDGSGKFQPHPDGFEN
AAALTRALKRLAPFEVSVAGYPERHPDSPSDQADLDNLKAKIDAGADRVLTQFFFAPEAF
LRFRDRAAAAGIGGEIVPGILPVVNAGQVRKFATACGAAIPPELDRMLEGLDERPEMRPL
VAAMVAGTLCQRLYAEGVRQFHFYTLNRAPMTQALCHLLSCQQKDISSAALSGR
>A8KZC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. (strain EAN1pec)|TrEMBL
MSTPTVAECLASGRTSFSFEFFPPKTTEGERHLWTALREIEALHPTFVSVTYGAGGSTRD
GTIRVTERIATETTLTPIGHLTAVNHSVGELRQVIGGYAGAGVRNVLALRGDPPGDPQAE
WVRHPDGLGHADELVRLVRSLGEFCVGVAAFPDKHPRSPDLETDARFLVRKLDAGADFAI
TQFFFGADDYFRLVERVRRLGCDAPIIPGVMPVTNVAQIERMAQLSGADFPADLAARLHE
VADDPAAVRAIGVEVATELSERLLAGGAPGLHFITLNRSSATREIYQSLGR
>A0A7Y7QED2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus rhamnosus|TrEMBL
MKISQCFKDHQVISFEVFPPRKNATNIAMRPILNTLDAVKAADPDFVSVTFGASGNKPHM
GTLEVAKLIKNEFNLEPVAHLPAAQLTRAQVDAELRGFQEAGIDNILALRGDIPKSGRVS
EDFPYACNLIEHIHQVGDFDVVGACYPEKHPESLDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYQFRERAALAGINVPIEAGIMPVINEHQIERMATMAGVHLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A7X0CEG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia aurea|TrEMBL
METPDFSIEFFPPKTPEGAEKLRVTRAKLAELQPRYFSVTFGAGGSTQQGTLQTVQEIQA
AGHEAAPHLSCVGATRESIRAVLKQYQDSGIRRIVALRGDLPSGYGGAGELRYASDLVEF
IRQETGDWFRIEVAAYPEMHPQARSPQDDLQAFARKVSAGADAAITQYFYNADAYFSFVD
NVRKLGVTVPIVAGIMPITNYMQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCEKLLAGGAPGLHFYSMNQAVPTTAIWQRLRP
>A0A7J4DTE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrodictiaceae archaeon|TrEMBL
MIKLVEVWVELEPTTRREKLEERLKKIKAYRIDALDIPDAPLGTPKAFAPLIACYIQATH
KIKAIPHLRLLDINTNALLNIVGGLLLCGIDSLVILRGDQPKYGNPVKELNTDDALQIIR
SKYGDKVNIGCLVSLRKNVDEIIKRIEKDYDFFLLLRAFGENLEKIKVLRRIRADAKLIA
YVIVCENENCRRLKDLLEGQPIVSVERLHAHLNRLIEYVDGILLSSPGSLDTIVKTLELL
DKMGIL
>Q9KNP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)|TrEMBL
MTLGHREYKMGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKTLQ
PKFVSVTYGANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQ
NIVALRGDIPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRK
VDAGANRAITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVP
NWMVKQFEGLEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGV
RPQA
>A0A7X5EAG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MIISKLFEQKKPVISFEIFPPKKEAELQNIDETLKTLATLRPDFISVTFGAGGSSADNRT
VKLAQKIKRDYDIEPLVHLTCISNSKEEIKEILGQMEMAGLKNVLALRGDVNPNVPAKDD
FKYASELVSFIKGQGDFHVSGACYPEVHLEAPDEVTDLRNLRKKVDAGAEHLVSQLFFDN
NKFYDFLSKVRIAGIDTPVEAGIMPVTNKAQIKRMVTICGASLPYKFERILERYGENKAA
LFDAGMVYAVNQIVELISSGVDGIHIFTMNNPVVARRICEEIKNLI
>A0A8J6MWB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfacyla euxinica|TrEMBL
MSELKSGSNLEKVLKAGHFAFTGECGPPKGANVEHLKEKIEPLKGMVDAVNVTDNQTAVV
RMSSWAASTIMCQEGVEPNFQMVCRDRNRLAIQADILGVYAMGIRNMLCLSGDHQRFGNH
PESKNVYDIDSMQLIALVKKMRDEGKFLNGEEIDVPPRLFIGAAANPFSDPFEFRVYRLA
KKIDAGADFIQTQCIYNMDRFKEFIKQAVDMGLYEKCYILAGVTPMKSVGMALYMAKQVP
GMDVPESLIKRLRGAGKGKAGEEGIRFALEQIEEFKEMEGVAGVHLMAIEWEHKVPEIAE
RAGVLPRPTV
>A0A1H6MDW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myroides aquimaris|TrEMBL
MKVTEHIQNANRKALFSFELLPPLKGQNIQCIFNTIDPLMEFKPAFIDVTYHREEYTYKD
AGNGLLEKKIVKKRPGTVGICSAIQNKYKVDAVPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKNGHRYASELVTQISELNNGIYLDDELENSHATDFCIGVAGY
PEKHIEAPNFDTDLQYLKQKIEKGADYIVTQMFFDNQKFFDFVDKCRNAGIAVPIIPGLK
PLTTKSQLNMIPHRFKVDLPDQLVIEALKAKDNEAVKQIGIEWCIQQSKEIIAAGFPVVH
YYSMSKSETIRQIAKGVF
>A0A7I6U758|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella sp. WP7-S18-ESBL-04|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A3D2TVT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKITQLLQEDKVTLSLEVFPPKKDTAVEQVSRSVREIAALQPDFMSVTYGAGGGTSAYTV
QIAKDIKAEYNVPSMAHLTCVSSTKETVKKQLECMQEAGIENVLALRGDIPADTEFPLPD
QFHYAVELVRYIKQIAPEMCIGGACYPEGHPEAVSKAQDIQHIKEKVDAGCEFLTTQMFF
DNSIFYNYMYRLREAGVLVPVIAGIMPITRKNQVERSIQLSGSCVPARFKSIVDWFGDDP
AKMKQAGIAYATDQIIDLIANGISHIHVYTMNDPEVAAGIMNNLSAILH
>A0A3B8U0K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MRISEILSSNPVTISMEVFPPKSDVKLESVRETVREISRLRPAFVSCTYGAGGGTSRYTV
EIARDIKDEGVASMAHLTCISSTRDSVHDQIEKIKA
>A0A238BPH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Onchocerca flexuosa|TrEMBL
MDGLAQISLRGLGQVIMDTIMDPVTVDNEAGTSRTKNDDGCVIDSSEITNQAAISSYPVS
NQWSESRTDWVTHGTYVPLRDRIKKRIAEGIPFFSLEFFPPKTRNSVANFFARLDRFREG
NPLFVDIAWHFGSDPGNINSETSSTSVAAGCLDYCGIDTVLHITCCSYTKEQSIRHLEQS
KALGLKNILALRGDLPRQDENPILYKYRALDLIRWIKEEYKDYFTIACSGYPAGHPEAPS
YRADLLYLKAKVDAGADFIISQIIFDGQVFEKFLRDCREIGITVPIIPGILPIQSYESIR
RIAELSQLIIPDSILASLEPIKNDDDAVRNFGIRYAVDLCQTLFTSGSATSIHLFTLNRE
ASSREILQQLGLWSRSPVRALPWRSFGENHPVRCKEDVRPIFWSLRPKSYVFRTREWDEF
PNGRWGNSSSPAFNDLKDYYLFYLKGQPTKIEQLRMYGERLETLADVQKVFINFIAQNIN
ENGVKVNQLPWNEQYDGIRAETSLIKDQLLWCNSNGFLTINSQPSVNGAPSTDPFVGWGK
PGGYCYQKAYLEFFTSQANAEILWNLLPSYSRLNCHIVNHDATIDWTNTETTMPIAVTWG
VFPGSEIAQPTVVDPLSFRVWKDEAFGAWLNWSSIYAEGTSSRCLLEKIYNEYCLVTLVD
NDYPKSTIIFDCLAQLVNKNFGKIL
>A0A3D2JK72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKFSDLMKKRQTLSFEVYPPKTEKGMNNLPGMIRRLGELQPDYISCTYGAGGSNVGKNRE
VLREVEKVAVPVTHLTCIGQTKESVRRQLQAYLDQGVTHILALRGDIPYGQSGTGGEFSH
ATDLVAFMRKEFGTAFEIAVAGTPGGHVECSSLEADIMHLRQKQDLGADYIITQLCFDMD
VFRRWYEAIRKAGITIPVDAGIMPVISKKSVI
>A0A0Q6PUI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia sp. Root112D2|TrEMBL
MTNDGSVNGSGVSGLLHDFSLEMTGKDIPALEEAKDSIPQGTRINVTFLGNEDLGMRVDA
SRAVLDNGFTPVPHISARRLSSQRELEEFLDALATRASVENVFVVGGDPATPMGPYEDSL
AVIRTGILQKYGVRHISISGYPEGHPDIDDATLWSALLDKSAALREQELEASVITQFGFD
TTPVLSWLKDVRGRGVDAPVRIGVPGPAGIKRLLSYAKRFGVSSSAGIVQKYGFSLTNLL
GTAGPDKFVRDLAAGCESEHIDSVLLHFYTFGGMKATAEWIRDFAERQA
>A0A1M6JHX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudozobellia thermophila|TrEMBL
MKITDHIKKAKGKTLFSFEIIPPVKGKNIQELYDNIDPLMEFDPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMREEKYFKPTQGGHSYAVDLVRQIQDLNCGNYLHDTVETDNCADFCIGVAGYP
EKHLEAPSLKSDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVDAAKAMGIDVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLVDAVDACATNKEVRQVGVEWCIQQSKELKDAGVPVLHY
YSMGKSDNIRAIAEKVF
>A0A350BXR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MRIPDIMKSRMSVSFEVFPPKADKPLDPLMRILDKLYTMQPDFISVTYGAGGSNTGRHME
ICKSIADSGKTMPLSHFTCIGSNKEDIRRQMDRCLELGIDNILALRGDIPQGWEGTRGDF
THASELIAFLREEYGDKFVIGMAGAPEKHIEAQTFAEDIAHLRMKQDAGADFITTQLCYD
VEGFKWWMDTIRKTGVTIPIDVGIMPVLNKNSIIKMCLSMNGCSIPQPLAELISRHYNDS
DEDFRKYGIEYTTNMVYEFMALGINGVHFYSLNKAEAVLEICRNCGLAYRK
>A0A5P9H9C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. THAF12|TrEMBL
MSAQEHPLGISFEFFPPNTEAGRDKLMQTRDALASRGPRFFSVTYGAGGSTQHRTTETVR
MVRESGFTTAPHLSCIGSEKAALRDLLAQYREEGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFNIAVAAYPETHPQAPNFDRDMENFARKMKAGANLAITQYFFTADAYF
HFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSESIAAF
GEDVISRLSQRLLDGGAPGLHFYTLNQAEPTLRVVDNICG
>A0A6B2T9N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID10116|TrEMBL
MTALRALIDQDTPSFSFEFFPPKSDAGARTLWKAIRRIETLAPTFVSVTYGAGGSSRDRT
VEVTKRIAAETTLRPVAHLTAIGHSVAELRHIIGQYADAGVRDVLAVRGDPPGDPGAPWT
PHPDGFTHAHELVRLVKESGDFSVGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQ
MFFDVEDYLRLRDKVTAAGCTTPIIPEIMPATDVRQISRFAQLSGAAFPEHLAHRLEAAR
HQPAEGHHIGVEHATAMAQRLLAEGAPGLHYITLNRSTATLEIHRNITDARSTPHDLAAH
H
>A0A351XJS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
DMCIGGACYPEGHPEADNKAEDIKHIKEKVDAGCEFLATQMFFDN
>A0A356DP61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MIQEKEHKGVVFSCEVFPPKRDDDIYQIYKTLDEIKTLKPDFISVTYGAGGSNSKKTATI
AAYIQNICEVEALAHMTAVGMDEASLRALLFELKKKGVENILALRGDKPRTMSQEEFDQR
YFKYATDLIPEIKKNGDFFIAGACYPEVHPESKNQEEDIQHLKQKVDLGLNCLITQMFFD
NNAFYSFMDKLEKADIDIPVHAGIMPVTAAKQLGTSVTLSGSSVPVEMSNMIAKYGENPE
DMKKAGIEYAVNQILDLKKHGVAGVHIYSMNKADVTKQIYEASF
>A0A1Q2ZT17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygosaccharomyces rouxii|TrEMBL
MSIRELYESKDGPTLSLEFFPPKTETGKQNLLERMERMTALGPLFATVTWGAGGSTAEKT
LELASLAQKNLNLPICMHLTCTNMDRNIIDDALTRCKAAGIHNILALRGDPPIGQDWSDL
EASQSEFKHAVDLVRYINYRFPNEFCIGVAAYPEGHCEGEAEGNEQNPWKDLPFLKEKID
AGADFVITQLFYDVDKFLQFEQMFRQHISTDLPLIPGLMPINSYLLFNRAAKLSHASIPS
SVLQKFPPEIQADDDAVKSIGVDILIEIIETIYKATHGRIKCFHFYTLNLEKAVAKIVAT
SPTLSDTLDVVEDENDEAATSEPEEQDQEGDIVLEDANVKNLIEDNRKRRRQSSTVSNVS
SELTSNRVIIGKKNQHGVGAPTRKVVISISQGSGTLGRDATWDEFPNGRFGDTRSPAFGE
IDGYGPTLKVSNKKAYELWGQPKTIQDLQIIFIKYLEGSIDALPWCDLGLSPETALIQEE
LIQLNERGFLTLASQPATNGSPSTNKIFGWGPAYGVVYQKAFIEMFVPKNIWENGNMKKA
IEQYGRAKLTYYANDSQGNFETNLESNSSNVVTWGVFSDSQVIQSTIVSEESFKAWSDEA
FSIWLEWAKLFPRNTSTNSLLRQIHQEYCLISIVHHDYINPDELWEIILS
>A0A349YS20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MNIADMFQEDRTVLSYEVFPPKGDKPIESIYDTLDELGRLRPDFISVTYGAAGNVANTAT
IDIAGYIQKQYQIQSIAHLTCVHATYANIDQILSDLKARGVDNILALRGDIVDGMEPKKD
FLHASDLAKYIMDKGGFHVSGACYPEVHQDAKNAIEDIKNLKVKVDSGVDHLISQLFFNN
TVFFDFVEKARIAGIDVPIEAGIMPVTNKKQIERMVTMCGASLPAKFVKVMQRFEDNPEA
LRDAGIAYAIDQIIDLVANGVDGVHIYTMNNPYVARRISEGVESIVRGSRRTSR
>A0A412DVU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus bromii|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYGAGGNGSKNRT
CEIASKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYIASQGDFDIAGACYPEVHSEAADEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A8D0DQU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salvator merianae|TrEMBL
MGSSINESLNMVNESFSHGSGVAIXANGSSGIKFDGGGLSSSSGCGSGSESSKDSSRCST
PVLDTERHDRLPEKMRRRQESGDKWFSLEFFPPRTSNGAVNLISRFDRMGAGGPLFIDIT
WHPAGDPGSDKETSSMMMASTALNYCGLETILHMTCCXQTKETITAHLQKAKRLGLKNIM
ALRGDPVGEAWEEEASGFNYAVDLVKHIRCEFDDYFDICVAGYPKGHPEAESYMDDLKHL
KEKVLAGADFIITQLFFRSETFLKFLRDCQAIGITCPIVPGIFPIQGYHSLRQLVKLSKL
EVPQEIKDVIEPIKDNDAAIRNYGVELAVTMCRELLNSGLVHGLHFYTLNREVATTEVLK
RLGLWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSS
PAFGELKDYYLFYLKSKSARDDLLTMWGEELTSEESVFEVFRCYLTGEPNKNGHKVTCLP
WNDDPLAPETNLMKEELAKVNRXGILTINSQPNINGKPSTDPIVGWGPDGGYVFQKAYLE
FFTSSENVKALLTVLKKYGQRVNYHIVNVKGENITNAPEMQPNAVTWGIFPGREIIQPTV
VDPVSFIYWKXEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLDSCLWQ
VLEDMYQLLNCPVEH
>A0A6G9ERT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. VN1|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPGADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVTHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPQLSNAAF
PAELKERILTAKDDPAAVRSIGIEFATEFCAALLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A800EA58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTEHIKNAKQTLFSFEILPPLKGTSIQSIYDSLDPLMEFNPPFIDVTYHREEYVYKKR
KDGLLERRAVRKRPGTVGICAAIMNKYNVDTVPHIICGGFNKEETENALIDLDFLGVDNV
LVLRGDPIKSETYFTADEGGHKYASELLQQVDGMNKGIYLDEELKNSAPTDFCIGVAGYP
EKHFEAPNMRSDIHFLKKKVEAGADYIVTQMFFDNQQYFDFVNLCRENDITIPIIPGLKP
ISTQKQLTLLPQRFYLSMPNPLVDEVLKCKTNEAVRQVGVEWATEQTKELIEFGAPCIHF
YTMGKSDNVQQIVGSFA
>A0A0H2X029|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus (strain COL)|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLYGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A7Y2A219|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVIEHIERSKKTLFSFEILPPLKGASIGSIYDSIDPLLEFNPAYINVTYHREEYIYKKK
ENGLLQRISVRKRPGTVGICAAIIAKYKIDTVPHLICGGFNKEETENALIDLHFLGIDNV
LALRGDPVKNEPHFVPNAEGHKYAVELVNQILELNNGNYLYEENQSDSFTDYCIGVAGYP
EKHFEAMNMNTDLQYLKQKVNAGAEYIVTQMFFDNQKFFEFERKCREIGINVPIIPGLKP
ITSLRHISFIPKFFHISFPDELADDLIKCRSNQEVNEVGIAWSIKQAKELMKHKVPSMHF
YTMGRSEAVRQIASAVY
>A0A0P0N486|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrodictium delaneyi|TrEMBL
MRILGELEPTKNNEKLAKRVEKLAGVVDAIDIPEAPMGKPIAHAAILAAYIKAKYGIDAI
PHVRVSDLNTVGLLSILGGLKATGIEEAVLLKGDQPIVGKEVEELTVESAAEVASSRLGG
KPRLGAMMSLRYPLEAITKRLQAPLDFYLVLRPSHSLEKLEQVSKLAKSLNKRLYTYVIV
ASSRNYSKLREMLVGQPVYNIDEAVRFVTKIQGLVDGILISSPGDVDTISETARRIKKEL
RLD
>A0A7Y7J4Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium Scap17|TrEMBL
MTSRLTIPDNTQLSPAEGVGNVGRLEQVLRSGQFAVTAELAPPDSADPQEVHARAQLFAG
HVDAMNATDGSGANCHMSSVAMCALLAREGHETVMQISCRDRNRIAIQGDVLGAAALGIR
NLLCLTGDGVQVGDHPEAKPVFDLDSLSLLEIVAGLRDKHTFASGRTLTSAPQVFLGAAA
NPFAPPFAFRPHRLAKKIAAGAQFIQTQYCFDLPRFQAFMHRARDLGLLEKCFILPGVGP
LASARTAEWMRRHVPGVHIPDDVLKRLKGARDQKAEGRDICIEMIQQLREIEGVSGVHIM
AHRQEAFVPEIIQRAGILGSRRPYTPQAPLGATSPIG
>A7BDK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schaalia odontolytica ATCC 17982|TrEMBL
MPFSDDTYACPCTHDHEPTLLSFEVMPPRRPSLEEPFWNTVDELLRVRPDFMSVTYGAGG
KDRSNARSTVHRLVRDTPIQPIAHLTCVGNSTEEVVSTVYDYLDSGVRTFLALRGDPPVG
QEGWEPGPGGVGSATELIHLIRTVEKRRCDAHPGEALRSAFKPLTIAVAAFPAGNPAAGT
TPAQEVERLLVKQAAGASFAITQLFWDAEVYASFVERARRAGVTIPIVPGLLPATDPARL
RRVQDLTGIEVPEYLLTTLADYPHQDARDEFGAVFGSRLIHSVLEAGAPGVHLYTFNRSK
PVLDILALMGVKPDLLRSQVSSPETRA
>A0A2D5PU33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MDIPSELSDGISKCKDNKEARQFGVEWAIEQCKELKASGVPCLHFYTMGNSDNVYKIASE
LF
>A0A2E0MGS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MLKDKILNKEAGIVLYGMTPPKENTDITLIKEIASKHVDRIKRLDIDGVVLYDIQDESAR
NNEVRPFPFLPTFEPQKYSGDFLAGLDLPKVLFQVVGKHSEGSLKNWMQNNVNNGDLGVF
IGNSSSSQSSQVSLEKAYSLRKEFASEMLVGGVAIPERHFAKKDEHLRIASKIKNGASYF
TTQAVYNIEASKNMLSDYYYYSTSNNLPIVPIMMTFSPCGSKKTMEFMKWLGIHFPRWLK
NDLTHSEDILGASIDTCVRTFKELVTFSLNKGIPIGANIESVSIRKDEIDASVELLENIK
DILNKSL
>A0A512PCY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas soli|TrEMBL
MSAATATAPRALTAPVDRPTVSFELFPPRNPDAAPKLWATIQALESARPDFVSVTYGASG
RTRQTTRQLVRRLLRETSLNPIAHLTCVDSSREETTTIVEEFLDEGVRSFLALRGDPPAD
AVDWHPHPQGLHTAADLVELLREIEGRRCAVSPAQAVRATVRPLSVAVAAFPRGNHATGG
TRAQDVASLLAKQQAGADFAITQVFFEADAYLGLVAEAREAGVTIPIIPGIIPTTDPDRL
LRVQDLTGVPVPRALLDVLGGADDETERHRRGIRACVDLVNGVLDGGAPGVHVYTFNQHR
AALDLLEGAHLGGSGEARQPL
>A0A089NUR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium oryzae CBMB20|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTEEMEKILWGSIERLAPLQPSFVSVTYGAGGSTR
ERTHNTVARMVRETGLKPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPAEGVGH
AYRPHPGGYASTAELVEGIKRIGDFKVSVSAYPEKHPEAASLDADIEALKAKVDAGADQA
ITQFFFENEVFLRYLEKVRAAGITIPILPGILPVQNFKQAANFARRTGASVPYWLAARFE
GLEDDVETRRLVAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQSPKLA
AAKAAA
>A0A239GA34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis indica|TrEMBL
MTSNLNSIAEARRAAASPLFADLDGDIGVSFEFFPPKTEKMEAQLWDTFHALEPLAPRFV
SVTYGAGGSTRERTHATVARIAKESRVPAAAHLTCVEASRDEIDAVARDYWDAGVRHIVA
LRGDVPGGAPYRAHPDGYANAAELVAGLKAIAPFDISVAAYPEVHPDAANATADLDNLKR
KLDAGATRAITQFFFSPDAFLRFRDAAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMVALFEGLDDHPAARQLVAATIAAELSRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVASAKDQAA
>A0A1G1IHX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium RIFCSPLOWO2_02_FULL_62_14|TrEMBL
MSTGPKRRLKDILDCGEFAVTVEYNPPKGTNASAILDNAKSLIGRVSGVNVTDNTAAIMR
ASSLSICRLLYEMGHDPVMQMTCRDRNRLAIQSDLLGAHLLGIRNILCLTGDYPTVGDHK
DAKPVYDLDSVQIMQLVQGFNQGRDLAGNKLDGAADFMIGAAVTPEMDPPGPMLAKFEAK
VNAGAKFFQTQAIYHADQFNSFMHKVRPFKVKVLAGILLLRSAKMAEFLNANIPGIAVPP
EMIAELRAAGPTREQEVGIEIAVRTIKAVRPHCDGVHVMALKAIDRLPEILTKAQLG
>A0A5S5CXB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus xanthinilyticus|TrEMBL
MTPTVRELLATERPTWSFEFFPPKTTAGEEQLWTALRRLEQLRPSFVSVTYGAGGSTREG
TVSMTERIAAETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WVPHPEGLRYAAELVELIRSMGDFSVGVAAFPERHPRSPDLDSDIDMFVAKCRAGADFAI
SQMFFRAEDYLRLRDRVAARGCDVPVIAGVMPVTDVRQITRIVQLSGQAFPADLADRFAA
LDGDRPEDKAAVRAFGVEVATELCSRLLDEGVPGIHFITMNRSTATREVFTNLAAGRSPD
LTD
>A0A0F2LB61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoproteus sp. AZ2|TrEMBL
MRPIAELPPAKDRDLLMKRIEAIKGLAEEVDVPDSPLGKPSAHAIAVASLALQAGLNPIA
HIRIRDINLLALKSLLGAAKLLGIRRVVPLMGDPPALGAPVDQLRTEDAVRAAKEEGLVV
GAMLSMRRNYAERLKIGADFYLILNLRRPEDMEGLRGVEAYPYLLIRTSRNAELMARLGQ
PSLSLEEVRRFLDALYSYGVKAVVVSAPGDFDAELAALGEFRR
>A0A5E9PF17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIDKVLHFSGK
ARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKNNYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYVEQYRHLELRALEELWISLWQVTTGKEFSPEITRFSR
QPTSKQLIKYRQLHVMHEAMFGSKIARGVGRFIFKASFWENTLVAKVLLKTEVLSKHSLV
GCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKALKQT
EILKEKLIPTVSLETRGTSSWKNWYLATEA
>A0A841BRQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allocatelliglobosispora scoriae|TrEMBL
MTLGAASTFPGARPTVAELLSSAEPAISFEFFAPKTPEGDQLLWQAVRELESLRPHYVSM
TYGAGGTSRDSTVAWTERLASETTLVPMGHLTAVGHSVDELRNIIGAYASAGVRNVLALR
GDPPGDPQAEWVAHPRGLNYADELVRLLRESGDFCVGVAAFPEKHPRSIDFETDVDYFVN
KCRAGADFAITQFFFRWEDYVRLRDAVAARGCDVPIVPGIMPVTNVKSIQTMAKLNGAGV
PADIAERLLAVADDPVAVRAIGVEVATDLCTELLREGAPGLHFITLNRSTATREVWQNLR
VGAEV
>A0A380HJ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus saprophyticus|TrEMBL
MSQLLDKLKHNILVADGAIGTILYSEGLDTCPEAYNITHPDKVARIHRSYIDAGADIIQT
NTYGANFEKLKPFGLEHKVKDIHYAAVEIAKQAANDDTFILGTVGGFRGIKQEDLELSSI
QYHTEIQIETLIDAGVDGILFETYYDLEELTTIIKATKRKYDIPIIAQLTALNTNYLRNG
TEINTALQQVVKSGADIVGLNCHHGPHHMQQSFSHIELPDGAYLSCYPNASLLDIENSQF
KYSDNAAYFGKVAEQLINEGVRLIGGCCGTTPEHIQYIKSSVSDLKPVNQKNVIPIAKYT
GHSEKPTQKQNLTSKVKHRPTIIVELDTPKHLDTDLFFRNIKKLDDAKIDAVTLADNSLA
TVRISNVAAASIIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKTQTNFNIAGAFDPNVRKLDGAVRR
LEKKLESGTHYFITQPVYSKEKIKEVYEATKHLDVPLFIGIMPVTSYNNALFLHNEVPGI
KLSEAILEQFEAVKDDRAKTKSLSIELSKALIDTVHEYFNGLYLITPFQKVDYTLELANY
SKSITSTKQEAIL
>A0A7H2V319|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MPHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDDDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHHYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLSLKALEELWNSLWQIT
SGKEFSPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENTLIVK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKEKLIPTVPLETRGTSSWKNWYLATDA
>A0A0V1H2E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella zimbabwensis|TrEMBL
LMASLDAVELKTTRHDLNSSPKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTPEGL
INLLNRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCVLNFCLLDTMLHITSVQY
NEKTVLSNLERVKKIGIRNILALRGDISDDANVTATDFQYACQLVQFIRSHYGDYFTICV
AEDLLNLKAKVDAGADFIITQLFFNEMHYFQFVSDCRKIGIVVPIIPGILPIQSYQSIMK
IVQLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVELCRKLLNAEQHVVPGLHFYTLNQ
EKSTRQKHTLLE
>A0A1Y3F5P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKTQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLESAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVIKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>B9KZH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2)|TrEMBL
MTDDVLSEAAIEATPDISFYCALLEELRIEVLPTVELEKVMATVPLGSTLTVTSSPAHGV
KGTLATALALRQHGYRVVPHLAARALRSHQELVLLWQQFVAAGIDEVFVVGGDQTEPAGE
FPDSRTLLTALVELQPRPRRIGIAAYPEGHPHIPADVLDADLLTKQALADYAITQLVFDP
DALVRWLTRMRSRGFTLPLYLCLPGTLRLDRLIRIGLRLGLGTSLRYLEKQRGLVGRLLT
GGIHYDPSDLLDELVRRPAAIQGGIVGIHWSSFNALASVVEWVAAKRARLGCPGEGVQA
>A0A125BCV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus denitrificans|TrEMBL
MAERTFSFEFFPPKTAEGMEKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETVRDIQA
DGSEAAPHLSCIGSTEDSIREILNEYKSQGIRHLVALRGDLPSGSMDAGAFNYANELVAF
IRKETGDWFEIEVAAYPEIHPQARSYTEDLANFKRKVDAGANAAITQYFFNADAYFNFVE
DARALGVTIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLEIYGDDLPSLRALGLDV
VTDLCDRLLAGGAPGLHFYTMNQASPSTTIWQRLGL
>A0A4R0E578|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4779|TrEMBL
MTKRVPISFEFFPTKTDVGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFTIEVAAYPEMHPQADSFDKDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRIKKESVNIPVAPGIMPIINASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A2Z6IMR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus ferridurans|TrEMBL
MAHSVEFFPPKNAAGEERLREAITALLPLDPEYASVTFGAGGSTRERTFATVTMIRQDYD
LEAVPHLSCIGSTEAGIREILEDYRKQGIRRIVALRGDLPEGMENPGHFQHAADLVAFIR
HFGGFEVYVAGYPDIHPRATSARNDVMHLAAKVRAGADAIITQYFFNPDAYLQLRDELQR
EGVEVPLVVGVMPITNFEQISRFSAMCGADIPQYLRRRMDAYAADPQSQYQLGIELLSRQ
CQLLLREGAPSLHFYTLNQAEATAAIWRNLGF
>A0A161LWN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paludibacter jiangxiensis|TrEMBL
MRVIDLINNSKTTAFSFEILPPLKGNSIDLVYKTIDLLRPFDPKYINITTHRSEIVYKET
GPNLFQRVAERHRPGTVAIAAAIQNKYKVNVVPHIICSGFSKSETEYALIDLQFLGITDL
LVLRGDKAKHDKAFMPGEEGHAHAIDLQQQINDFNSGKFMDGSIIKQPVSTFSYGVAGYP
EKHDEAPNLDSDIHWLKEKVRLGAEYVVTQMFFDNEKYYAFVDRCRKEGITVPIIPGLKP
ITLMNQLTVLPKIFHVDIPEPLATELAKCKTDAEALEVGVEWCTMQALDLKQQGVPSIHF
YTMMATQSVKRVAEKVY
>A0A150V4P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidomyces richmondensis BFW|TrEMBL
MHITQKLAAAHSVGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGGRMS
NLTTEMVKVAQSVYGLETCMHLTCTDMAGSKIDQALKDAYQSGCTNILALRGDPPREKEK
WEQTDGTAFRYARDLIKYIKSKYGNHFEIGVAGYPEGLDDETDADSHIPYLKEKIDAGGA
FIVTQMCYDAETFISWEKKVRAAGIPKSVPILPGIMPIQTYDSFLRRAKWTNARIPPEWM
EALDPVKGDDAAVREVGKGLVAEFCRKLLDAGVTMHLHFYTMNLAASTQMVLEELSVTPT
TNTVHPDIKPLPWRQSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPA
FGSLDAYGIGLKGTNEHNREVWGEPKTLQDIADLFVGYMRGQVKSLPWSEAPITSEADVL
RNDLIELNSRGLLTINSQPAVDGAKSTDPVYGWGPRNGYVYQKAYLEVLVPPSLLPTLIE
RMEANEDITYYAVNNSGELKTNVDDKAGSGPNAVTWGVFPGKEIIQPTIVETISFLAWRD
EFYYLGTEWSKCYDENSESRKLIKEIVESWYLVNIVHNDFRNPRGIFPLFEGLIVEGVIP
QPKKAAINGHTEMNGVGANSVV
>A0A6P5UD17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila obscura|TrEMBL
MEQRLWHCIRRLAPLAPRFVSVTYGAGGTTQTGTLSTVLRLKRETDLIPAAHLTCVGATH
EDVDDLARCYRDAGVNHIVALRGDPPAGAADYSPRPGGYAYASDLVAGLRRIADFDISVA
AYPETHPAASSPDADLDNLKRKLDAGATRAITQYFFDSEIYLRFLDRCLAAGITAPIIPG
IMPVSNYEQIVRFSAVCGVTVPAWLRHLFDGTS
>A0A7L8UEQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. MDT1-60|TrEMBL
MKVTEHIENAKGNTLFSFELIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKVGGNSFAIDLVRQINNLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQIF
>A0A8E0B1T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus 58-424|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>W1X3K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|human gut metagenome|TrEMBL
FPPRTSEMEQTLWNSIDRLSNLKPKFVSVTYGANSGERDRTHSIIKGIKDRTGLEAAPHL
TCIDATPDELRTIARDYWNNGIRHIVALR
>A0A854KEE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar shandongiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTNRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQVALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A809NL13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter cinaedi (strain PAGU611)|TrEMBL
MFGIEFLPQEIYEDIECLKAMIQGARENLGQEVDFVLIPSNPVNKASISSLLGAYALRER
FSMIVDSGFSSVVEFVPTISGAGQDKLQIFSQILSVKYGGFSSVALIGGDNGELDGVKLI
ALAREILGGEVSLVSGSGVKIWKKEIEQRLTQKLQAGVDRIITQPIFSIESAKKCVEHFY
VLQERLGIQAQLSLGVFGIFSAESAYRINKSHLGFDIPRSYLRALEQGGVKEGFESLWQD
MQGLAREYNVSLYLSTPKHNDLRAYGNGLC
>A0A1F4YJD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium RBG_16_48_11|TrEMBL
QHCFDEVNLSNPKLVQQIHQDYIQAGAEIIETNTFGANLIKLATHGLENKVRDVNFRSAK
IAREAREIVGKPVFVAGSIGPLGKPLEPIGKITKTEALGYFRQQAEALLEGGVDLFILET
MVNLEEMKQAVLAVKQICQLPLIAQMTFTEEGKTIMGNTPEEVVTELESLQVDVIGANCS
VGPLGIFEVIQRIVGKTKLKVSAQPNAGLPRLVDGRFIYLSSPEYFAQYALKFAAAGVSL
IGGCCGTTPGHIRAMYDALQSFQKSASDVTISTNRVTVAIPKTDKVETVAPPQTELSGFA
CKLKQKKFVISVELDPPKGVNPEKLLEGARAIKKAGADACNIGDSPMARVRMSCLALAYL
INDKVGLETVLHFTPRDRNLMGIQSDLVGAYALGVRNILCITGDPPSLGDYAHATAVYDV
DSIGLTKIISKLNQGTDVAGNSIGSPTSFFIGVGVNPGEENISREIDRFHQK
>R5YUV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:156|TrEMBL
MNIADLFEEGKTIFSFEVFPPKKESGIETVYDTIEKLTDLKPDFISVTYGAGGSGVTNPI
TKDICSKIKNEYKLETIAHLSCINNTKDEIDKILEELKKEGIDNILALRGDRVEGLEPKK
DFTYASDLTKYIMDKGGFHVSGACYPEVHMEAKDAVDDIKNLKKKVDAGADHLISQLFFD
NRVFYDFLERARIADINVPIEAGIMPVTSKSQIERMVTMCGASIPASLSRIMQRYESNPE
ALRDAGIAYAINQIIDLAANGIDGVHIYTMNNPYVARKITEGVESVVKHNR
>A0A7D5DYD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mannheimia pernigra|TrEMBL
MNYATQIDALNQHIADISRKINVSFEFFPPKNEKMETLLWDSISCLSPLKPKFVSVTYGA
NSGERDRTHSIVKSIQEKTGIISAPHLTGIDATPEELKVIAKDYWHSGIRRIVALRGDVP
QGYDKALFYASDLVALLKSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVSIGIDCEIVPGILPVTNFKQLKKMATVTNVKIPVWMGKIYEGL
DNDQTTRNLVAASIAMDMVKVLSREGVNDFHFYTLNRSELTYAICHTLGIRPQ
>A0A7U7JSP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus argenteus|TrEMBL
MSRFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIESGADVIQT
NTYGANFEKLKRFGLEDKVKDIHQAAVRIAKKASNKDTFILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLVEEGVDALLFETYYDLEELTNVITRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEQAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQSLKPVNDKKVIPIPTKA
LFNPSQHKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A6A7XYL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Segnochrobactrum spirostomi|TrEMBL
MTPTPRLSRAGGAPVSVSFEFFPPKTEEMERNLWTAVERLAPLRPSFVSVTYGAGGSTRE
RTHATVARILRETDLKPAAHLTCVAASRAEIDTVVRGYHEVGVRHIVALRGDPAAGPGNA
YEPHPDGYAFTADLIRGIRAIGDFEISVSAYPERHPESPTWDVELDILKRKVDAGATRAI
TQFFFDNDLYDAYVERVRAAGIDIPILPGILPVLGLAQVKNFAARTGATVPAWIAHRFEG
LEHDPATRQLVSAAVAAEQALDLVDRGVTDFHFYTMNRADLVYAICHLLGLRPTPLAEAA
>E8KVN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus vestibularis ATCC 49124|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLGKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHGATHSLFKHHSQVSSL
>A0A1C6VS53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora citrea|TrEMBL
MALGLPSVLPNPQPAIGELIREHQPTFSFEFFPPKTEQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPEGVLYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTEHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFSKIADDPEAVRRLGVEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLQ
VGARV
>A0A1B9M6Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVQPKDDF
RYASELVTFIKENSDFNVIGACYPEGHLEASTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYTFLDKARDIGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPEAF
RDAGIAYAIDQIVDLVSQNVNGIHLYTMNNSYIARRISEAVSTLLAVPKSE
>A0A1F8WHP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium GWA2_45_12|TrEMBL
MNFTDFYKPGTCRYSFEVFPVKTEEGVKNLLQVLGELKDFDPAYVSVTYGALGSTRDLTR
DLALRIHRGTKIPTAFHFTCVGSGRQEIKNYVEKLKKEGLNLVVALRGDPPKGGAFIPPT
DGFRYANELVTYLKSINGFSMAVAGYPEGHPEAGSKEADLVNLKRKVEAGADAVITQMFF
DNRDYFDFVERAHKVGISVPIIPGIMPILNLKQIEKITGLCGAKIPSQLHQRLVQCGEDV
EATRNVGIEHALKQCHELKKSGVPGIHFYTLNKSLSVAGIIENL
>A0A4R3Y5A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Testudinibacter aquarius|TrEMBL
MSYAKEIDHLNHSLANLNGEINVSFEFFPAKNEKMETLLWDSIHRLAPLKPKFVSVTYGA
NSGERDRTHGIVKRIQQDTGLIAAPHLTGIDATPDQLRVIAQDYWDSGIRNIVALRGDEP
PGYAKQPFYASDLVKLLKEVADFDISVAAYPEVHPEAKSAQADLLHLKEKVAAGANRAIT
QFFFDVDSYLRFRDRCVAVGIDVEIVPGILPVTNFKQLQKMATLTNVKVPSWMPKMYQGL
EDDQTTRNLVAASIAIDMVKVLSNEGVKDFHFYTLNRSELTYAICHMLGVRAAV
>A0A1H8QKI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. ap11|TrEMBL
MYPTAFRPSRESRRPIRVSFEFFPPKTPEMEATLWSSIERLAPLGPSFVSVTYGAGGSTR
ERTHNTVSRLVRETELKPAAHLTCVAATKGEVDDVVRAYHEAGVRHIVALRGDPADGVGT
AYTAHPGGYERSCDLVAGIKRIGDFEVSVSAYPERHPEAGSLDQDLDALKAKVDCGADRA
ISQFFFDNDLFFRYLDRVQSRGIDIPIIPGILPVQNFKQAANFARRTGASVPDWLAARFE
GLEDDVATRKLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRAAPAAAE
KAAA
>A0A2D7BK89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MTDLKDAIAAAGQHWSIEVTPPGATKIDSFAEILAPDTTVNVTFLPGTDPMDTVDVAVRL
RDDGMNPVPHIAARSVQSRDQLGSIVKEMASRANVDEVLVIGGGVDNPVGDFASSMEILE
TGVLQENGISRIGVSGHPEGSPDINDDQLAEALEWKNDFARREGLELYIETQFCFEADPV
IAWENRIRARGNDLPIRIGIPGPATIKTLLRFAQISGIGPSMRMITKQARNVTRLLTVQS
PHTLITGLAEAMANDPESRLSHFHYYPFGGFARTEKWATAVAAGDFDLLPKGGFSVKEN
>A0A1T3P2Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Embleya scabrispora|TrEMBL
MSLGAAATRISRTPAIRDLLADGTRSFSFEFMPPRTEAGTRTLWEAIRRVEALAPTFVSV
TYGAGGSSRGLTVDTTERIATETTLTPVGHLTAVGHSRAELRNIIGQYANAGVRNVLALR
GDPPGDPKGEWIAHPDGFTYAVELVELLRASGDFCVGIAAFPEMHPRSSNWDEDIRHFVA
KCRAGADYAITQMFFDVEDYLRLRDRVAAAGCDIPIIPEVMPVTSPTTLVRADELSGCSV
PADLSAAVAAVGDDRAAVRAIGVEYATRMSERLLAEGAPGLHFITLNRSTATTEIYQNLG
LDGDAGAARGAGSTEIG
>A0A498DLD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariprofundus sp. EBB-1|TrEMBL
MKLSEILSNADKPLISCEFFPPKTDKGEENLWNCLDELRGIDPAYISVTYGAGGTTQGRT
KGIVTRIKDETGLSPVAHLTCVGASKEQLAELLSEYRAAGIENILALRGDAPEGMDRFEA
AVGGFSYATDLIAFLRAQGDFSIACATYPEGHPESKGGVADDIRYLKMKQDNGADCAVTQ
YFFDNETFFRFRDATEKAGVTIPIIPGIMPVGNFDQIVRFSGMCGASVPDWMREQMEPIK
GDLQAVQKLGIELAAKQCRGLLEADTPGLHFYTLNKSAATIAIRNQLTDLL
>U5E3W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia asteroides NBRC 15531|TrEMBL
MVRSLQTHAGSGVPFSVEFNPPRDAAGEARLWRAVREFECMHPAFVSMTYGAGGSTKDRT
VRITGELATETTLLPVAHLTAVGHSLDELRALVGSYADSGIRNLLVLRGDPPGDPLGEWR
KHPEGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLDHDTRQLAAKLRAGAEYSITQ
MFFDVEHYLRLRDRVVAMDPIEGAKPIIPELMPITSLRTVQRAEELCGRPLAPAVLDRLT
RAAGTGPEEDKAAVRAEGIQIATEMAQRLIDEGAPCLHFITLNFAKATSEVLTNLGYGVT
AAPLSA
>A0A2H6BV88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa NIES-298|TrEMBL
MTTRLQRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQIACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGSLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPVHN
>E3CSA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus vestibularis F0396|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLGKEKVAETLRDLDAVGVHRILALRGDIIPGVEPLKDFSYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHGATHSLFKHHSQVSAL
>A0A833A6R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrodictium sp|TrEMBL
VVCWCVKLVEVWVELEPTTRKEKLEKKLEKIKTYKVDALDIPDAPLGVPKAFAPLMACYI
QAVYGVKVIPHIRLLDINTNALLNIVGGLLFCGVDNFVILQGDQPKYGNPISELNTDDAL
QVIRSKYGDRVSVGCLVSLRKNVSEIVKRIVKDYDFFLLMRAVNENLEKIKVLRQIRADA
KLIAYVIVCESENCKRLRSMLEGQPIVNVERVDEHLNNLVEYVDGILLSSPGSIDTIVKV
LELLNEIGIL
>A0A7C7UHN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKLKEALEKRKFVITTEVQAPIDEEPQELVKRLELVRGRVNGVTVPELDIEGIVGDSIKT
CELLKQNRFEPIYQTTTRDKSRIQLQKDLIHAHEVGLENLLVFTEDYRITGDSLQEIMFF
HVDSGKLASVLEHMREGNGVDGKELPFKVEFVLGSGVESGWGKNVPELEMKEMEEMKKIG
TRYFLTTPVFDLALFEKFMKQVETFEVPVIAEVMILRTAGMAQFLNRHFKSGLVPDWIIK
RLAKATDRQKASIEIFAEIAGGLKDLCQGIHIITIGGDEKLRHYLDAAKLR
>A0A7W2YHJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. 5Ae-yellow|TrEMBL
MALSLKEKIVDTNQGVYLIGTTPPKIGTDKAQLKIIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQARPFAFKQTVDPREYSHLLRNLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDL
QNVVLVGSPSSIGDIKLSLPDAYKALAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGIIPQRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKVTMELNLAEKLIA
>A0A7C4MZK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKTDSVLEKILAAGHLAVTSECGPPRGAVPEKVREKAEKLRGYVDAINVTDNQTAMVRMS
SFAACLIIRQMGLNPILQMVTRDRNRLAMQSDILGAYAHGINTMLCLSGDHPCFGDHPMA
ANVYDLDSIQFIQMVRGMRDNGKFQGGDEILNPPKMFIGAAANPFADPFELRVARLAKKV
KAGADFIQTQCIYDLPRFEKWMEGVRDRGLHEKVAILAGVTPFKSVGMAKYMKNKVPGMS
VPDEMIKRLSGVPKDKQPEEGIKICVETMQRLKEVKGVAGFHIMAIEWEEKVPEIVQRAG
LHPRPSV
>A0A7C0YHW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MVVMIDQADALLIMSCAFGVQTIARQFPVKVLAGIILLTSAPMARFMNKNVAGVNVPQSL
IDEMASAPKGKAIDKGIEIAGRMVRRIREEKMCHGFTLWPLVGKNWSQRSWQPLDCYKGS
AYFSITAGTSNESLMASVTAFTWLDSTRPMIE
>A0A7C3L9I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MNFKESLFNPDEFTLTFELVPNRAGHGHGQNRILQLARQAAADGRLRAVSITENAGGHPA
LSPEVLGIEIQAMGLPVISHFSCKDKNRNQMESLLFGWDRAGLQNLLVISGDYPQHGYCG
KPKPVFDLDSVQALDLISQMNNGQTECLTNNKDMIFQPTTFLKGVAVSPFKSLPQELLFQ
YMKLHRKAVAGADYIITQLGFDARKFEEVLLYTRLTGLDLPILGNVFIPNMKVAGLMYRG
EVPGCVITDGLYNDMCREANSADKGKRARLLRGAKLLAILQGLGYAGAHIGGPGLTFADL
DLLMSEAAKMAADWRSLLPDLSYWPADGCYFFEFDPQTGLNLNEEAGLDKLPLPALPLSY
RLSHFVHQTFFEPDGAFYGPTSKICLSMGSGGREKMLANIEHIIKLIIFDCQNCGDCRLS
DLAYLCPQSGCAKYMLNGPCGGSRDGWCEVYPGRKRCFWVLVYERLTAHGLSFANNIIAS
PRDWGLNKTSSWLNFFRNQG
>A0A7Y3AF76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MISSFKKALDSDKFVITCEVAPPKGTNLDKTAHHIDLLKDKVDAMNLTDHQSSVMRYPSI
GGALLVKEMGGEPILQMTCRDRNRLALQADLLFAASRGVHNVLCLTGDSVMLGDHKQAKG
VFDLDSSQLMDAIRTLEKGKDLGGSDLDGSPAFCAGAIVTPEANPLEPQLIKFEKKIAAG
AEFIQTQAVYDLDKLKTFMEYARQFPVKILAGIILLTSAPMARFMNKNIAGVNVPQVLID
EIAQAPKGSAVSKGIEIAGRMIKRIHAEKMCDGVHIMAIGKEETVPDIMAAAGLTP
>A0A179B2H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptidiphaga gingivicola|TrEMBL
MPPRRPENTPAFWTMIDRLLAVQPDFVSVTYGAGGKNRFSARDIVTRLSRDTPVNPIAHL
TCVGTSVRTVESVIEDYLDADVRTFLALRGDPPADDPDWRPPPGGVSSATELVALIRSVE
TRRCAANGSAALRAAVSPLTISVAAFPSGNPAAGTNPEQEVERLLLKQAAGASFAITQLF
WDAQTYISFVDKARQAGVYIPILAGLLVPSNLRRLSRTCDLTGITPPDSLVERLRAADNA
EAASLCGVAEAARIAREVLESGAPGLHLYTYNKPEPALALLEQIGLVEPAESVEPSAGVK
PSES
>A0A1V3JI54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter genomosp. 2|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMENMLWESIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKKIAQDYWDSGIRRIVALRGDEP
KGYDKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHIIT
QFFFDIDSYLRFRDRCAAIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPNWLAKAYEGL
DEDPTTRNLVAASVAMDMVKILSSEGVNDFHFYTLNRSELTYAICHMLGVRPSV
>A0A0F8V329|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus ochraceoroseus|TrEMBL
MHIKEKLAQNEAAGRIGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPRERVDAALQSAYKAGCTNILALRGDPPREKEV
WEAADGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSSF
VVTQMFYDTDHFINWVKKCRDRGINVPIIPGIMPIQTYAAFIRRANWTKARIPPDWLEAL
EPVKNDDAAVKEIGKRLIADMCRRLIAAGINHLHFYTMNLAQATQLVLDDLKLTPTPETP
LQRALPWRPSLGLNRREEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDA
YGIGIKGTNDQNIKLWGEPKSLRDLADIFVRFMEGKLERLPWSESPISAEATSIKENLVE
LNKRGLLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLLPPYLINDLIARIEANE
DLTYHAVSKSGELLTNTRDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYQLGEDWA
KCHDAASPSRKLIQGVMDNWYLVNIVNNDFHNTYNLFELFNDLNVKDLDVEVAGEIVEPK
ALQNGTTNGTTNGATPEPVAQN
>A0A367EEV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces reniochalinae|TrEMBL
MAIGISAPRTDRPPTVRDKLASGEQSFSFEFFAPKTEKGERTLWNALRRIEAVSPTFVSV
TYGAGGSSREGTVRNTERIANETTLTPVAHLTAVNHSRTELRNVIGQYADAGIRDVLALR
GDPPGDPLGEWVKHPEGIGYAAELVELIKESGDFCVGVAAFPEMHPRSSDWDTDIRHFVN
KCKAGADYAITQMFFRAEDYLRLRDRAAAAGCPTPIIPEIMPVTNVKQIERFAQLSNATL
PDGMVERLRAVEDDPAAVRSVGIEYATDLCARLMAEGVPGLHFITLNHSTATLEIHQNLG
LRQKAQLS
>A0A1Q2LEP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter bilis|TrEMBL
MLEQLITKLQSNEPFLSVEVSPSLSSTIGQSVIDELESLSQADCFVCTDSPLARLKPSSI
LSSIKLQNALKKPLICTLSMRDRNSIALCGDILGANEFGLRSFLSLSGDGVKNGDCAGAK
GVFEESSLKLGRIIDGLNQGIAANGKVLKDSVETIYNFSVINSYANNTESLKKKMLKKLS
NSAVQGLFTQPVFSLEAARFLLESMESINKELGQNCVMILGFFPVLSYKVALFLRDKLPG
VYIPNEWVQKLEKASIKGKEVERKIGLELSRELFKDLQTLHNKFHFMSANKPSLLREFVQ
D
>A0A351B491|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MEPKTPSKLEKIMAAGHLGVTSEVGPPRSCDGAEIEHKGHLIKDYVDAVNVTDNQTSVVR
LCSLASCIRLKQMGIEPILQMTTRDRNRIAMQSDILGAASFGIHNMLCLTGDHQTFGDHP
MSANVFDLDSVQLIQTVKLMRDEGKLLSGFEMKVRPQIFIGAAENPFAGPNVELRALRLG
KKIAAGVEFIQTQCIYNIPKFKEWVKIAVDKGYADKAYIMAGITPFKSLGMARYMK
>A0A351B490|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
VVRMSSKAASAIMVQAGLEPNFQMVCRDRNRLAMQADILGAYAHGIRNMLCLSGDHQKFG
DHPGARGVFDIDSMQLIALVKQMRDSGTFLSGAELHGVPKMFIGAASNPFAEPFEWRVHR
LAKKIEAGVDFIQTQCIYNIPKFKEWLKIAVDRGLTQKVHILAGITPFKSLGMARYMKSR
VPGMDVPDNLIERLKGVPKEKQAEEGIRLAIEMMQELKGLNGVKGFHIMAIEWEEKVPEL
VKGAGLYPRPTA
>A0A840HT66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizorhapis suberifaciens|TrEMBL
MPRHPYGGSQALCALLNNYSVEMTAKDVPELEAAADSIPPGTKIPVTFLPGETFDDRIAA
AKHVRELGFIPIPHISARSLESQEELESFLSGLQREAAVDHAFVVAGDPPQPMGPYEDAL
SIIRTGLLAQYGIRRVGISGYPEGHPDIGNDKLWRAKRDKQAALHDRGHDFAVVTQFAFD
AEPVLSWLEQVRAEGVDALVRIGVPGPASVKRLLSFAARCGVGASAKVMRKYGLSITKLL
STAGPDALIKDLADGLDPSKHGDVLLHFYPFGGLRTTAEWIREFRRRQGC
>A0A7M1L324|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas thiooxydans|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPEFCSVTYGAGGSTQAGTFTMVRDIQSE
GVGAASHFSCIGATHEKVRAELNELKAMDVKRIVALRGDLPSGYGLGGEFQYASDLVAFV
RQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VRALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>W4C6I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL R7-269|TrEMBL
MKPDLRSAWEKGVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYINAGAVL
LESNTYSANYDKLSKFGLEAKVADINRAGVRIARRAAGENGYVVGAIGSIRAGKRANLSS
SELKKFFSQQIAALLEEAPDGIMLETFYDVEELHLALKAVRKLSTLPVICQLAVDDSART
LDGLTLPEAFHILQQDGADVIGFNCNTGPNGIKRALGTLQGKLALPVSIYPNAGVADYVD
GQYRYGASPEYFGQMAPVFADMGSRIIGGCCGTTPKHIAEISAALKDYAVEPLPEPAAFS
APESIAVQEHLADDGGQRGGEPTLVDLVKERHTVIVELDPPRDLDIAKFMKGAEALRRAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIKQLNDGVAFSGKPLKQNAKFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIARIAKATEHLDIPIFIGIMPLASGR
NAEYLHNEVPGIQLSAEVRSRMAGLEGEAGRAEGVLIAKELLDAAIAHFNGIYLITPFMF
YDMSVQLLEYIWEKQGRKLSPLFR
>A0A1M4TVT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria intermedia|TrEMBL
MTKPEISFEFFPPQTLEASFRLWDTVQTLAPLGPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLPVAAHLTCVDASRDETLGIAEEFAAAGVTDIVALRGDPPKGQDRFTPHPDGFATSV
ELIAALAQTGKFKIRVGAYPDIHPEASDAQADIDWLKAKLDAGADEALTQFFFEAETFFR
FRDACAKAGIDKPIVPGILPIENWTGARKFAKRCGARVPGWVEDAFEKAIRDDRHDLLAT
ALCTELCSDLIEGGVDKLHFYTLNRPELTRDVCFALGITPKVDLQHVA
>A0A6N8DPP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoblastus acidophilus|TrEMBL
MDANRPSRKRHKPCQVSFEFFPPKTDDMEANLWEAIGRLAPLKPKFVSVTYGAGGSTRER
THATVARIVRETNIAPAAHLTCVGATREEVDEVARAYWEAGVRHIVALRGDPQGGLGGEY
TPTPGGYAHSTDLVAGLKRLHDFEITVSAYCEKHPESASYDQDLDVLKRKIDAGATRAIT
QFFFDNDIYFRFLEKARKAGIDIPIVPGVTAVQNFKQTANFAKKAGASVPDWLAERFEGL
DDDPATRRLIAAAVAAEQVFDLLDRGVEQFHFYTMNRADLVFAVCHLLGVRAA
>A0A7L9GKV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas taiwanensis|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A692RAG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MLKKKIKDNTPGILLYGLTPPKLNLTHEEAIIVAKKQLERLENRGIDGLVIYDLQDESNR
NKSERTFEFCGTIKPEIYHKEFLKLAYPAVIYKAVGNYTQDEFCRFLNDSGENLSVFVGA
SSKKDSPKLSLDMAYKLKKEQGRDITLGGICIPERHEKKGDEDLRVAGKTIKGCEFFITQ
AVYNLENAKRFLDDYSNLNIKKVPIIFTFTPCGSLKTLEFMRWLGISVPKQFENRLFKSD
DPLKASISLSLDMFEFLFKYGKAKGISIGANVESISTRKVEIEASVELVNGIKSIIS
>A0A6F9MTK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIADILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVNAGTDKLITQLFYNNEDFYTFKQNC
ALANINFPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAV
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEEIRA
>A0A847I6S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
QVKRFTRTCGASIPTTLMNELHRLQDDPHAVLSMGVAHATAQCIELLQRGAPGLHFYTLN
KSPATRTILTAIRTVYPPANSPAGT
>A0A2T4HYN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas fennica|TrEMBL
MDAPLFADLAGDCQVSFEFFPPKTEKMEETLWNAIETLAPLGPRFVSVTYGAGGSTRERT
HATVARIARETAIPAAAHLTCVDASRDEILDVAREYWAAGVRHIVALRGDPPREGEKFQA
HPDGFENAAALVAGLKSVAPFEISVAAYPECHPDSTDVAADLDNLKRKIDAGANRAISQF
FFSADAFFRFRDAVEAAGIDAEIVPGILPVSNVAQTRKFAGMCGAAIPAWMDRLFEGLDD
RPAARQLVAATIAAEMCRKLYAGGVRHFHFYTLNRAELSYAICHLLGLRPNPAAAEKAA
>A0A1G6EEN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium MAR_2010_188|TrEMBL
MKVTDHIKKANGKTLFSFEIIPPKKGKNIKELYDNIDPLMEFKPPFIDVTTSREEYIYIE
KEGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFSREETEYLLVDCHYLGLDNV
MALRGDAMPHQKYFQPTQGGHCYAVELVDQIKNLNKGQYLHNVVEVDDKSNFCIGVAGYP
EKHIEAPSINSDLKRLKQKVDAGADYVVTQMFFDNKDYFNFVEKAKEAGINVPIIPGIKP
FATKSHLQLLPQVFKIDLPEALIAEVEKCTTNKQVREVGVEWCITQSKELLAAGVPVLHY
YSMGKSDNIKAIASSVF
>A0A1F0AXH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC057G03|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFAHQPNFEVN
>A0A2S6C4D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cercospora berteroae|TrEMBL
MHITEKLQQAHGKGKATCSFEYFPPKTAQGVQNLYDRMDMMHGLGPAFIDVTWGAGGRHS
SLTCEMVKVAQTAYGLETCMHLTCTDMERSKIDDALKEAYKAGCTNILALRGDPPREQEK
WEATEGGFRYAKDLITYIKKTYGDHFDIGVAGYPEGVDETCGADEHITYLKEKIEAGGTF
IVTQMCYDADIFIDWVKKCRAAGIPESVPIIPGIMPISTYAAFLRRANWTKAHIPEHWME
KLEPIKNDDSAVRAVGCDLIVEFCQRLLDFGLMHLHFYTMNLAQAVKMVLEKLDMIPEAE
SPHPDIKPLPWRQSLGLNRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
GLDEYGIGLKGTNEHNRKIWGEPKSIQDIANLFVGYMSGKVESLPWSEAPINEEANTLVD
DLVQLNSRGLLTINSQPAVDGVKSSHPTYGWGPRNGYVYQKQYLEVLVSPALIETVIARM
NNDPEITYYAVNCNGELKTNAPPDGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYH
LGLEWSKCYEEGSESRKIIREVTQNWYLVNIVHNDFRQQQGIFPIFDGLKAPGLEPAEVN
GVNGHAETNGVAPETNGVPDGNNVVNGADKVASSNSAQTA
>A0A451D650|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MITIFKDRKKKYNHEVVNLKNKIKISFEVFPPKNIVLENKLFHSVKMLNKCNPEFFSVTS
SINIDKYDKTFSVLKKIFPLTNAKLFAHFITVGLNESLIKEIAYKYWSYGIKNIIALRGD
LPFNYSKKVIYAVDLIKLLKSVNDFKILVAAYPELHPESHSLKEDLINLKNKVDLGVTAA
ITQFFFSINKFLKFRDNCLMMGLKIDLIPGILPILNINQLKKFVNMTNIYVPQWILDFFY
EHSNDIDKCTDLSVSIAVDLIVSLYREGIKNFHLYTLNQSDLSLKICHKLGLI
>A0A4U0T7Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces oryziradicis|TrEMBL
MSYGEREDVRGAVAALATGANVEVIPLRGVEQKLSEIPINTTVTVTCSPKFGLDRTLDYA
ELAVKTGHRVVPHLAARQVADKAELLGFVRRLDALGVKDLYVIGGDAATPAGDYTSAAEL
IEALGAIDHGLERIGVACYPEGHPKIADNELLDALRRKQPHAHYMVSQLCFDVDTLVSWL
RRMRSAGIELPLRLGLAAPMNILKLTELSIKIGVGSSVRFLTKQHGLVGSLLRGSSYQPE
ELLYRIGAELTSDELRIEGLHLFSFNQISATVGWQQRVGGAATVQRI
>A0A4Q0UTT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter aquimarinus|TrEMBL
MFETLIQKLQEDKYLTLETTPQHEPSMHNIIERIKKFKLHEKVDGFSCTDNPLAKLKYNA
LFASLKLQQEFNKPVIATMSMRDRNKIALQSDLMGANDFDVRAILALTGDPAKMSDQPHA
KGVFEANSLMLLKIIKSFNYGMDFAGRPFKIEPKQIFPFAVVNSYAKNFSTLERKMNQKI
QNGAIGIISQPVFDIENAKKLLESFNIAKQDVEGDKQKAQLIFGLFPVTKLRTALFLSAQ
VPGIHVPQFWIDALENAHNISEEEEHKVGLQLSSDLFKEINKLHPKIHLMTANRFDIANE
IIS
>A0A0D3CUV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica oleracea var. oleracea|TrEMBL
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNAICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAYGIHFATEMCKKILAHGITTLHIYTLNVDKSAIGILMNL
GLIDESKITRSLPWRPPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYSTLSDYQFMRPRARDKKLQQEWVVPLKGIEDVQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TLVEKSKAFPSITFMAVNKAENWVSNIGESDVNAVTWGVFPAKEVNQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNDYINGDIFSVFA
>A0A4S8X888|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MDRVHLFLFFILFFIAKRLISRHRQVNRRAAAKEKKATYSFEFFPPKTAQGVQNLYDRMD
RMHNFGPSFIDITWGAGGRHASLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEA
HDAGCTNILALRGDPPREKEKWEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDD
NDNPEELIQHLKEKVDLGGTFIVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHA
AFLRRANWSNIHVPPHWHEALEPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMN
LAQSTRMILEELSITPSQDTPLEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDW
DEFPNGRWGDSRSPAYGELDTYGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVES
LPWSESPITDEADALRKDLINLNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAY
LEVLVSPELISELITRMERNPNITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPT
IVETVSFLAWRDEFYRLGSDWSRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFP
LFDELEVPDLNKEIAAPEAPQKVNGATNGEKNEEEPKVGNGDVTDSKIPDSAHKKLETQI
NGAEEKPDTEPKDATAHNTGAGPSTSV
>A0A1M7DU36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius litoreus|TrEMBL
MTAPKVSFEFFPPKTLEASFRLWDTIQVLAPLDPRFVSVTYGAGGTTRELTREAVGTLHK
ATGLNVAAHLTCVEATREETLAIADSFHEAGVTEIVALRGDPPKGSGGFTAHPDGFANSC
ELIEALADTGKFTIRVGAYPEKHPEAADAKADIDWLKRKLDAGAAEAITQFFFEAETFFR
FRDACVKAGIDAPIIPGVLPIENWTGVRKFATSCGTTIPAWLDDTFDKAIRDNRQDLLAT
ALATELCSELIEGGVEHLHFYTLNRPELTRDVCHALGVTPKATLRDVA
>A0A4S9QF55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDGALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSIANS
APQNRVVIDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPSGFVFQKPFVE
FFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLL
EA
>Q2SLT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hahella chejuensis (strain KCTC 2396)|TrEMBL
MESQTQFKRRFSFEFFPPKTPEGMEKLQVVRDKLAKRKPDFFSVTYGAGGSTRERTIDTV
LTLHRQGISTAPHLSCIGATKESIGELLDLYRSNGIQRIVALRGDLPSGMGAPGELRYAN
ELVSYIRERTGDHFSIEVAAYPEFHPQAQNAEADLNNFRRKVEAGATSAITQYFFNADSY
FYFVERCEKAGLNLPIVPGIMPITNYSNLARFSDMCGAEIPRWVRKQLEAYGDDSASIRK
FGEEVVTRLCERLLAAGAPGIHFYTLNQAEPSLAVWDNLNLGDKISF
>A0A3D3CK47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
LGVVNSLNNGKDMSGNEMKGSTDFFQGAVVTPEANPLEPQLIKFEKKVRAGARFFQTQAI
YDINKFKEFMQYARKFPVKVLAGIVVLKSAGMANFINNNVPGIRVPIELIDELKAAGKEK
ALDTGLNIAARHIKQLKEENICDGVHIMAIGMEDKVPVIMERAGLL
>A0A3N6NVY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania hirsuta|TrEMBL
MNRFRNAVKSGEFLVTAEVAPPKGADPAHMIEMASTLKGRVHAVNVTDGSRAVLRMSSLA
ASIILKNNGIDPICQVACRDRNRIGLQADLMGASALGLHNILALTGDPVKAGDHKDARSV
FDMESVRLLQMIAKLNQGIDWNEKTLPDGATDLFVGAAVDPQSPSWSGLKKRFERKLLAG
CQFFQSQLISDFDKLEKFMNQIAVESNKPILAGIFLLKSAKNAAFINKYVPGVDIPEHII
NRLAKAEKPLEEGIKIAAEQVQIASKICHGVHLMAIKREDLIPRILDMAEISPIEQ
>A0A1W2BIC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKIIDILSRNEMSLSFEVFPPKVETSFENVMAAAGKIAELKPSFMSVTYGAGGGTSKYTL
KMSSEIEHRYDVPMLAHLTCISSDKATVRERITELKEAGIHNIMALRGDIPADRINEDRS
HWDYNYAVELISEIKSIYPDCCIGAACYPEVHPESSNQREDIRRLKEKVDAGADFLTTQM
VFDNNLFFNFMYKLREAGVTVPVLPGIMPITKANQVERAIKLSGSFMPERFRSIVDRFGS
DDAAMTQAGIIYATDQIIDLYANGITNVHVYSMNKPEVAAGIKNSLSSILGKEF
>K8MJK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. F0441|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1S9CTH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epulopiscium sp. Nele67-Bin004|TrEMBL
MKLNYLFKENKPVLSFEIFPPKKQGDWLPEIYDTIDALAPLGPDFISVTYGASGSSQSNT
VEIASLLQKKYSIPSLAHLTCVGDTDDMITNVLTRLKDEGIQNILALRGDLVGDNKLGDF
KYASELTEFIKNYSDFCVAGACYPEVHPDAPNLEEDIKNLKIKADAGAEFFITQLFFDNA
TFYEWRNKVREAGITTPIVAGVMPITSAQQLKRMATLCGATIPENVKTLVEAYEHNAYAL
RQVGIAYATQQILDLLANGVDGIHLYTMNKPHITKQIMDNIRGPLYSLKGKN
>A0A424KDW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutales bacterium TMED207|TrEMBL
MESQTIIHTIASGKKTLSLEFFPPKSDKAIQQLKESSRDLAKLSPDFVSITYGAGGSTRK
STFTYAEQLKTDHDYKVMPHLTCVGHSQNELAEIIQQYQEAGFRTLMALRGDPQGDSQTF
TPHPDGFQFANQLVAFIKSQFPNFEIGVGGYPEKHPESPSQTNDIQNLKKKVDAGADFIT
TQLFYNNDHYYRFVDQCRDAQIDCPIIPGLMIPTNLERVERFCHFCQAELPDSLKAALSS
AHEDSQALQDVAVEWTFQQVKALLENGAPGIHLYIMNQSKFVLALYQKLREADHLFHT
>A0A8C9V2L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scleropages formosus|TrEMBL
MVNQVQRMDGGSQAPKSDSSGASNSGGESSKESSRCSTPLLDADRADRLREKMKRRIESG
DRWFSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKDQITAHLAKAKRLGLKNIMALRGDPLADVWEEEECGFNYAT
DLVKHIRWEFGDYFDICVAGYPTGHPEAESYEADLKYLKEKVDAGADFVITQLFFRAETF
LKFVKDCRAVGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEAMMQVIEPIKDNDAAIRN
YGIQQAVDMCKVLLQSGDVPGLHFYTLNREVATMEVLKQLGLWNEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LVKMWGEELMSEESVFEVFTNYITTQPNRNGHKVMCLPWNDDPLAPETNLLKGELEKVNR
RGVLTINSQPNINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVQGKNITNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKVGSHFSPGLESR
TALGFISRTLGMSALGLPPCPAFQPSE
>A0A8J7SYM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Odyssella sp|TrEMBL
MTAPAVSFEFFPPRDDAGWAQLWATIGKLAPFRPGFVSVTYGAGGTTRERTDRIVRRIRA
ETPLEPAAHITCVGAERREIDALATSWWDAGIRHLVALRGDPPAGGAKYVPHPGGYENAA
ALVAGLRKVAPFDIAVAAYPEKHPDSPTVAADLDNLKRKLDAGGTSAITQFFFDAGAFLR
FRDRARAAGIAAPLVPGILPITNFARAVEFAQRCGASVPAWLAELFHGLDDDPEQRNLVA
AATACDLCEKLAAEGVDRFHFYTLNRPQLTAAICRRLGLKPAQEAG
>A0A416SWW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. AF19-12LB|TrEMBL
MNIADLFEEGKTIFSFEVFPPKKESGIETVYDTIEKLTDLKPDFISVTYGAGGSGVTNPI
TKDICSKIKNEYKLETIAHLSCINNTKDEIDKILEELKKEGIDNILALRGDRVEGLEPKK
DFTYASDLTKYIMDKGGFHVSGACYPEVHMEAKDAVDDIKNLKKKVDAGADHLISQLFFD
NRVFYDFLERARIADINVPIEAGIMPVTSKSQIERMVTMCGASIPASLSRIMQRYESNPE
ALRDAGIAYAINQIIDLAANGVDGVHIYTMNNPYVARKITEGVESVVKHNR
>A0A7H1BDA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces xanthii|TrEMBL
MALGTASTRTDRARTVRDMLTPGKATYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHITAVEHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWLAHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSADWDSDVRHFVD
KCRAGADYAITQMFFYPEEYLRLRDKVAAAGCDTPIIPECMPVTSVRMLERLPKLSNADF
PPALKERILTAKDDPAAVRSIGIEFATEFCAKLLDEGVPGLHFITLNNSTATLEIYENLG
LHDQRA
>A0A7Z9D7F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella multocida|TrEMBL
MSYAKEIDTLNQHIADLNGKINVSFEFFPPKNEKMENILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLDAAPHLTGIDATPEELVEIAKDYWNSGIRRIVALRGDEP
KGYAKKPFYASDLVSLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLVKMAAITNVKIPAWLAKNYEGL
DDDQTTRNLVAASVAMDMVRVLSREGVNDFHFYTLNRSELTYAICHTLGVRPA
>A0A7K3VVD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus sabuli|TrEMBL
MAKTLTVRDPGSRASLKRVFQTLGYEVIPFKKTEENVLKYVPKDVRLTVTASPAKGQDAT
VDLTVKLREHGYTVAPHLSAQQTLSRQHLAEIVARCREAGIHEVFIVGGDPTDTPTEFKD
AHALLVALHELDHGFTDIGIGGHPEGHPSVSDDVLFDALAAKAPLAHHIKTQIVFDPKVI
LNWARELKRRNIDLPVHIGVPGAVTRAKLMRVSGGLGIGESAKFLKKQQSLFWRFFIPGG
YNPDKIIKGLLPHMGKADNNIENFHIFTFNDLEPTEAWRTSTLENLSS
>A0A418IIW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus xylosus|TrEMBL
MSQLLDKLKSNILVADGAIGTILYSEGLDTCPEAYNLNHPDKVERIHRTYIEAGADIIQT
NTYGANFEKLKAFGLEHRVKDIHQAAVQIAKKAANDDTFILGTVGGFRGIKQEDLELSSI
QYHTEIQVETLVNAGVDGILFETYYDLQELTNIIEATKRKYDIPIIAQLTALNTNYLRDG
TEINHALQQVTSSGADIVGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSQF
KYSDNASYFGKVAKQLINEGVRLIGGCCGTTPEHIQYIKSSVAGLNPVTQKDVIPITKYI
NNTEKEPKKQNLKSKVENRPTIIVELDTPKHLDTETFFRNIKKLDDAQIDAVTLADNSLA
TVRISNVAAASIIKQRYDIEPLVHITCRDRNLIGLQSHLLGLSLLDINEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKTKTNFNIAGAFDPNVRKLDGAVRR
LEKKLESGMHYFITQPVYSKEKIKEVYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSDEILEQFEAVKDDKAKTKALSLKLSKELIDTVHEYFNGLYLITPFQKVDYTLELANY
SKTITSTKQEAIL
>A0A1V3BNM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioalkalivibrio versutus|TrEMBL
MSAQERVYSVEFFPPKDEAGAERLAKARKRLGALKPEFYSVTFGAGGSTRDRTLETVRDI
IDNDGIPAAPHVSCISSTKDELRDLLSTYRDSGVKRIVALRGDLPSGTKHSGGDFRYASE
LVEFVRAEFGDQFKIEVAAYPEFHPQAPNAEKDLENFKTKVDAGADAAITQYFYNPDAYV
AFMERVEKMGITIPIIAGIMPITNYTQIVRFSEMCGAEIPRYIRKRMEAYGDDKESIRKF
GIEVATRLTDDLLAHGAPGIHFYSMNQAGPTEQIWKALDLDNRK
>A0A1F8XDS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium GWA2_65_63|TrEMBL
MKKAPLIFDGAMGTVIYDRGVFINTCYDELCLTNPKLILQIHRDYVEAGAEVIETNTFGA
NPIRLKPYGLAEKTEAINRAAVRLAREAAGEEVFVAGSVGPCTESRQRMPEEFAPEVEGA
FRTQMEALAAEGVDLFLLETFSHLNELQLAARVAKEFGRPVLASFVLNDRGETALGMRAE
TMASALSADDNVDIVGINCGTGPSGTFDALQAILPLTRKPVVAMPNAGMPREISGRVMYL
TSPEYFTEYAKKFIELGVRGVGGCCGTTPAHIRMAARAVKPLRVMKRRVEAKPLLRQETL
VYAVPTERKSRLAAKLCAGRKVTSVELVPPKSSDMTALLAKARQCAEAGVDAINIPDGPR
ASARVSPMISALTILQEVGIEPILHYCCRDRNLIGMQSDLLGGYAAKLANFLIITGDPPK
LGEYPDVTGVFDVDSIGLVQVAANLNRGLDIGGNPIEPPTGLFIGVGANPCAVDMEREID
RYFRKIDAGAEFAITQPVFDPEALLRFLDRVGTYRRKIPVLAGVWPLLSFKNAEFMNNEV
PGVVVPKPILDRMARCKTREDGRKAGIEIARGIVERISDRVDGFQVSAPLGHVETALAVL
AKSF
>A0A8J7AN58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|aff. Roholtiella sp. LEGE 12411|TrEMBL
MLDTQKPTYLTAFQTAAKEGKFLITAEVAPPKGGNPAHMISMAATLKGRVHAVNVTDGSR
AVLRMSSLIASAILLQKGIEPICQIACRDRNRIGLQADLMGAHALGVHNILALTGDPVKA
GDHPDAKAVFDLEAVRLLQLIRKMNQGVDCNDKPLTDGALELFAGAAVDPQCASWSGLQS
RFERKIEAGAQFFQSQLITDFERLEKFMDKIAAGYKKPILAGIFLLKSAKNAQFINRCVP
GVNIPEHIIDRLAQAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIAPILDLAGV
APVNLMVVK
>A0A6L8MGK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella lactea|TrEMBL
MTNPNFSIEFFPPKTAEGAEKLRATRTKLSELKPKYFSVTFGAGGTTQQGTLDTVVEIMA
AGQDAAPHLSCVGGTRESIRQILTEYKSHNIKRIVALRGDLPSGYGAGGEFRYANELVEF
IRQETGDHFHIEVAAYPEVHPQARSPQDDLLAFERKIKAGANSAITQYFYNADAYFQFVE
QAQKLGIDAPIVPGIMPILNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VSALGERLLQGGAPGLHFYSMNQAAATTALWQRLV
>A0A828U2P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli DEC2D|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPLGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A807CAV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium loti NZP2037|TrEMBL
MSARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A7J7ZZI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myotis myotis|TrEMBL
MRRRMESGDKWFSLEFFPPRTAQGAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKETS
SMAIASAAVNYCGLETVLHLTCCRQSQEEITGHLHKAKQLGLKNILALRGDPVGDQWEEE
EGCFRYATDLVKLIRSEFGDYFDICVAGYPKGHPDAESFEDDLKHLKGKVSAGADFIITQ
LFFEADTFFHFVKACSAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQKIRDVIEPIK
DNDAAICNYGIDQAVSLCQELLASGLVPGLHFYTLNRRMATTEVLKRLGMWAEDPRRPLP
WAVSAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGHSSSPAFGELKDYYLFYL
TSKAPREELLKMWGEELTSEESVFEVFVHYLSGEPNQSGCTAYLEFFTSRETVGALLQVL
KKYEQRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFA
LWVKQWGKLYDEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPGAR
ADRLRDPAP
>A0A6I5UBZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora terminaliae|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRHVIGRLASVGVRNVLAVR
GDPPGNPGGEWIKHPDGVRYAEELVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQLGTIERSVQLSGAPF
PPALAERFAAVADDPEAVRRLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWQRLR
ADARV
>A0A135WD17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium kwangjuense|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTPGGHASAMDLVHQINDLGRGKYLHNDEKASDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKEKVDAGADYIVTQMFFDNKRFIEFVTKAREMGISVPIIPGI
KPIATKKHLKILPQVFKIDLPEELITEVENAKNNEAVKQIGIEWAITQCKELLDFGVPVL
HFYSMGKSDNIKKVARELF
>A0A099D7V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora erythraea|TrEMBL
MTTNAHQQLQRYLRNSRYEVLPLRGVVEQVRELPAGTTVTVTSSPAKGTEATLDTAARLR
DEGMHVVPHLAARLVRDSAHLTDLLAHVDDLGLTEVFVIAGDAERPAGRFTDALSLLRGM
EEIGTRPYRLGITGYPEQHAFIPDRMTIQATDEKARYADYIVSQICYDPNTIASWVKSMR
ARGVELPVYIGAPGSIDPSKLLRISMKIGLGQSMRFLRKQHGVVSKLLTRYTPENVFDEL
SPYIVDPAYNIAGWHLFTFNEITKTRQWVVEMADRLQEVPA
>A0A1B3NEN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. RAC05|TrEMBL
MNAFRPSRHGSRRPKVSFEFFPPKTAEMEVSLWESVRRLEPLAPSFVSVTYGAGGSTRER
THATVKRMVEETGLKPAAHLTCVSASRDEVDEVIRGYWEAGVRHVVALRGDPAGGLGTVY
EPHPDGYHQTSDLVAGLKRIGDFEVTVSAYPEKHPEAASLEADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRAAGIDIPILPGIVPVQNFKQTANFARKTGASVPQWLADRFEGL
EEDAATRRLVAAAVCAEQVLDLIDRGVGDLHFYTMNKADLVYAICHLAGVKPERGEAQAA
AAE
>A0A3A9SRJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. CB08|TrEMBL
MKITDIFKEKEVTLSFEVFPPKTDAGYEAVEKAAAEIAALKPDFMSVTYGAGGGTSKNTA
AISSDLQDKYGVTVLSHLTCVSSTKETVKSMIEEYKSRGIENIMALRGDIPKEGRICYDY
DHATQLIYDIKSIDESFCIGGACYPEGHIECARQSEDIEHLKEKVDAGCDFLTTQMFFDN
STLYQFLYRIREKGIEVPVLPGIMPITNAKQVSRSVALSGSTIPQKMKIMVDRFADDPDK
MKEAGIIYASDQIIDLISNGVSHIHVYSMNKPDIAAGIMRNLATIIR
>A0A2R4EZX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax avenae subsp. avenae|TrEMBL
MSLSTHKADLPVSFEFFPPKTPEGADKLRAVRQQLYALRPEFCSVTYGAGGSTQEGTFGT
VREILSEGVQAASHFSCIGATREGVREQLAQLKAMGVSRLVALRGDLPSGYGAGGEFHYA
SDLVAFIRAEAGDDFHIEVAAYPEVHPQARSPEADLQAFATKVRAGAHSAITQYFFNADA
YWRFVDDVRALGLDVPVVPGIMPIMGSTQLMRFSDACGAEIPRWIRLRLQGFGDDSASIR
AFGLDVVTALCERLRAGGVPSLHFYTMNQSAATLEICRRLGL
>A0A219B272|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pacificimonas flava|TrEMBL
MSLQRSERERAFASPLFADLAGDISVSFEFFPPKSERMEETLWNSIAALAPLKPNFVSVT
YGAGGSTRERTHATVERIVKETDLTPAAHLTCVDASRGEIEDIARAYWDAGIRHIVALRG
DPPREGERFSAHPEGYDCAASLVEGLKKVADFEISVAAYPEIHPEAESANGDLDNLKRKI
DAGATRAITQFFFSPETFLRFRDDAVAHGISAPIVPGILPVTNFKQTSKFAALNGTDMPG
WLERLFDGLEDKQDARNLVAATVAAELCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLR
PSSPKIESQAA
>A0A255GCP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enemella evansiae|TrEMBL
MPFAKTEGLVLEHVPTEVPLSITVTEAKGLEPTLALTERLTQQGYRATPHLAARLFTGDQ
QVAEVADRLTEAGVTSIFVIGGDAPEPAGEFTDARGLLDSLERQGRRFETVSIGGYPEGH
AKIDDATLSEALRAKAPHANGLITQACFDAKVLGAWAADVARDGISLPIKVGLPGPVNRQ
KLIRISAGLGLGQSARFLAKQQNMVWRFLLPGAYDPMKLVKKLGAVTARTPTHIAGLHLF
TFNEVAGAERWRQRLLTATREGH
>A0A2U2HHE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia glaciei|TrEMBL
MDTSNFSIEFYPPKTAEGADKLRVARAKLAGHNPKYFSVTFGAGGSTQQGTLDTVREILA
EGHVGAPHLSCVGGSRESVREVLNQFKLAGVSRIVALRGDLPSGYGGAGEFRYASELVEF
IRAETGDAFHIEVAAYPEVHPQARSPEDDLQNFARKVRAGADAAITQYFYNADAYFQFME
QSRRLGIDVPVVPGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQAGPTTALWQRLAGK
>A0A2E4DAC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovoraceae bacterium|TrEMBL
MTKIVDHIQNAKGKTLFSIEILPPMKGHGVQSLFNEIEPLMEFDPKFINVTYHREEFQYK
KRENGLLEKISIKKRPGTVGICAALMNKFHVDTVPHIICGGFTKEETENALIDLQFLGID
NVLALRGDAIKSENRFAPTDGGHSYATELIEQINNMNKGKYLSSEIENAYPTDFCIGVAG
YPEKHFEAPNFQTDLKYLKQKVEMGAEYIVTQMFFDNNKYFDFVARCRDAGINIPIIPGL
KSLKTARQLTILPSIFHIDLPDDLVAAVEDCKNKEDIKKVGVEWAIQQSKELKERGAPCI
HYYSMGKSDDVVQIAKEIF
>A0A1H0LVM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter litoralis|TrEMBL
MTSPAVSFEVFPPKSVDASFRLWDTAQALAPLAPRFFSVTYGAGGSTRDLTHDSAHVLRR
TSGLPVAAHLTCVGASKAETLEVANSFAEIGVTDIVALRGDPENGAATFTPHADGFADSV
ELIEALANTGKFTLRVGAYPEPHPESPDQAQNVEWLKRKFDAGADEAITQFFFEAETFLR
FRDACAAAGITKPITPGIMPVTNWKSARNFATRCGASVPAALDEAYAAAIRDDRHDLLST
ALCTEMCSELVSEGVENLHFYTLNRPELTRAVCRALGVTAQTSLSDVA
>A0A1I4PAI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas yangmingensis|TrEMBL
MTSPSTPVSFEFFPTKTDAGHEKLLAAARVLAAEKPEFFSVTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDSKEELRSLLKQYRDAGIKRIVALRGDLPSGMGQASGELRYANE
LVEFIRAETGDHFTIEVAAYPESHPQARNFEVDLANFVRKAKAGADSAITQYFFNADCYF
QFVERVRQAGVEIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSDSIVAF
GTEVISSMCQQLLDGGAPGLHFYTLNQAEPSLAVWHNLRG
>A0A0S1SEY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sediminicola sp. YIK13|TrEMBL
MKVTDHIKNAEGKTLFSFEIIPPVKGKNIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIQNV
MALRGDAMKDEKYFNPIQGGHTYATGLVKQIQNLNRGKYLHEVIETDECADFCIGVAGYP
EKHLEAPSLQSDLKRLKEKVDAGADYVVTQMFFDNQKYFQFVEAAKAMGINVPIIPGIKP
IAIKRHLQLLPQVFRIDIPQELIEAVDDCKNNAAVRQIGIEWAIQQSNELKAAGVPVLHY
YSMGKSDNIKAIAKGVF
>A0A3M5V3H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. avii|TrEMBL
MDCVCLPGFRVSKGITMSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGA
GGSTRDRTINTVLQLESEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLP
SGMGMASGELRYANDLVSFIREESGDHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGA
DSAITQYFFNADSYFYFVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRK
QLEAYGDDVKSIQAFGEQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A6J4R4D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Solirubrobacteraceae bacterium|TrEMBL
VLALRGDPPQGQTVWPATEGGLSYSRELIELIRDDYDFAIGAACFPEVHVDAADAESDLR
YTKEKVDAGAGFLITQLFFDNAHYFDFVARARAAGIGVPIIPGIMPITNYAQLRRFTDMC
GAQIPAGLLAELEARAEDPDAVADFGVAYATLQCADLLANGAPGIHFYTLNRSPATRAIL
SALRTMVPWRASVTA
>A0A840U4R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter oulmenensis|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQATRDKLAEVGPDFFSVTFGAGGSTRDRTIETV
VNLHKQGISTAPHLSCVGGTRQEIGELLDLYKENGINRIVALRGDMPSGMGASGELRYAN
ELVAFIREHSGDHFNLEVAAYPEFHPQARSAEDDLNNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRQ
FGEEVVTRMCERLLKAGAPGLHFYTLNQAQPSLNIWKNLGIGDRQKIAF
>A0A7J9K3H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium armourianum|TrEMBL
KIQSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTADLTLDI
ANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQVEG
GFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKRKVDAG
ADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKIPAEII
AALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLGLIEES
KISRSLPWRRPANVFRVKEDIRPIFWCVIDVELQCLWLYIFSLVRCLTVLRVT
>A0A0B0HSK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus sp. BCO1|TrEMBL
MLGTIGGLRSTNKSTISLEEVKRTFREQLYVLLNEGVDGLLLETYYDFEELQTVLSIARK
ETTLPIIAHVTLHDIGVLQHGMPLAEALTELEQLGADVVGLNCHLGPYHMLRSLEEVPIP
TRAFLSVYPNASLPQYRDGRFIYETSEQYFEETARAFREQGVRLIGGCCGTTPKHIAAIA
RALSDRTPVYKKEVKQRHPIVVQEEKQTTAPSLADIARTRRSIIVELDPPKKLGLTTFLE
GAKALKEANIDALTLADNSLATPRISNVAVGTIVKQQLGMRPLIHITCRDRNLIGLQSHL
MGLHTLGMTDVLALTGDPSKVGDFPGATSVYDLSSFDLISLIRQFNEGFRTQQTARTKNE
LFDRCRL
>A0A357XWK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MSFTEALRSGVLVFDGPMGTELYRHHVFTNRCFEELNLSDSKLIERILTDYREAGAEVLT
TNTFGANRPALEKYGLADKLADINFTGARIARTVADRGAEQGNGHGDDSTRRCFVAGSIG
PILSSGSYNDEQIVAFFLEQIDPLLEGGADLIIFETFPSRAMVELAAKAVAHRPDTPYII
SCAIDHGIWNIAGEPIGRLFAPLPAELRPPTAWGLNCGVGPDGILEALEEAVRVTRIPIV
VQPNAGTPKEFEGRHIYYSSPEYVATYAMRFVNLGAAAVGGCCGIMPDHIREVVAMVKPL
ARGRETKSVLLSMEPEVEEKPESLFAERSRFACRLASKQWVTTVELVPPRGYDLEGTIRK
CKMLHRHGIDAVNIPDGPRASSRISPMVVAQRIHREACIEPILHFCCRDRNLIGMQADLL
ACAASEIRNLLFVTGDPPKLGGYPHATGVFDTDSIGMCAVQRRLNRGVDLGGQSLEPPTQ
AVIGVGLDPTSLDRKRERDRFRAKIDNGAEFAITQPVFDPEALLRMLDEIGDCPIPIIAG
VWPLAGYRNAVFMQNEVPGVVIPEATMKRMEEAAHTSQEHQWSVGVAIAKESIAVVQNRV
AGVQVSAPFGRIEIALDVLT
>A0A6B3GS81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7982|TrEMBL
AKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A8I1M7A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira povalilytica|TrEMBL
MTVQEKQAARNDLRVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGTTRDRT
HGSVTRIQGETGIPAAAHLTCVGHTKDEIEQIARKYWDEGIRSIVALRGDLPDAGDTYEP
TPGGYPYAVDLVAGLKEIADFDISVSAYPEMHPDAPSADFEIDYLKRKIDAGANRAITQF
FFDNETYLRFRDKCDAAGITAPIVPGILPVTNFASLLKFADMCGASVPERLHWRFDGLDE
DPETRRMVAFHEAISQVEGLMKEGVSDFHFYTLNRAELTYAICHALGIRGTEKAAA
>A0A356AER9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MNRLPDLLKSDSPLISIEIFPPKTEKGDELLYETLDTLSKFEPKFISCTYGAGGTTQTRT
LELCQHIQKTYEIPATAHFTCVGSSRDELIAWLDKAAAAGIQNIMALRGDAPKGETSFKA
VEGGLSYANELVSLIRERHPNMGIGVAAYPEKHAECLDADLDLANLKRKIDAGADAAFTQ
LFFDNDLFFAFRERYEKAGCAIPLIPGIMPITEFSRIKRITEMCGTAFPAELSVRLENVQ
DDADAQLEIGIEFAIAQCQELLENNVPGIHFYALNKSQACQRILEALKTS
>A0A6C1E1T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces pastorianus|TrEMBL
MSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKT
LALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVE
AGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
AILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETVANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWET
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKA
WRDEAFSIWSEWAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETDELWEMLLDQA
>A0A3D2TFH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
ALRGDPPQSETEFVAPRGGFGYANELVEFIRQQFPAMGIAVGGYPETHQEAPSPEADLVN
LKRKVDAGADAIITQLFFDNRDFFDFCDRCEQIGIHVPIVPGLLPITNGAQIQRLATLCG
AKMPKTLVEQLHQHADDPQGQFNIGVEFATRQTSELLEAGVAGLHFYVLNKSEATDQVLR
SVHWPR
>A0A2T2V3Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QS_9_68_14|TrEMBL
MKVTEHLNSPEPCISYEIIPPKRGGSGEDILEVVEELMPYDPAFIDMTSHAAEAEYVETG
DGTWKRRVTRKRPGTLGLCAAIQARFGVDTVPHLLCKGFTREETEDALIELNYLGIENVM
ALTGDDPGYEKDIAPGRSRNERAIDLVGQVDDMNRGIYLDEMTDTAPTDFCVGVGGYPEK
HIEAPNLTWDVLHLKRKVDAGADFITTQMFYDNEAYFEFVERCRDVGIDVPIVPGLKVLS
KKRHLNFLPSFFHLNIPEALAAEVEAASDREEVEEIGVDWAIQQAQELLSAGAPAIHFYI
MSSARLAKRVVGPLRETVA
>A0A346SLT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria sp. AD91A|TrEMBL
MNGAHRSEVEPIGYVPVPEGYVSHSRLERVLRSGRFAVTAELNPPDSADPEDVFQAAQPL
GEVADAINATDASGANCHMSSIGICALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAALG
VSNVLCLTGDGVGVGDQPGAKPVFDFDSLTLLRTIRTMRDQGKFLSGRKITRPPQLFLGA
AENPCIPPYDWRPERLAKKVEAGAEFIQTNYIYDIPLFERFMGRVRDAGLDEKVFIIAGV
GPIASARAARWMRSNVPGIHIPDHVIERMEKAEKPAEEGKKICIELIQQIRDIAGVSGVH
VMAYRREHVVSEIILESGALKGRKRTRSS
>A0A354PFU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MSLASHYRPGRCGLSFELFPPKPEAMSDLRETVERLVDFHPDFFTCTYGAGGSSQAATLD
VVQMVRQITGAPVASHLTCVGSTVEQLVAYLQEAKRRGADYIVALRGDPPKGTTEFAQVA
GGLRYANELVSLIRNEFDDDFGIAVAGYPEVHQEAISAEIDLANLKRKVDAGADIIVTQL
FYDNADFYRFRDDCESAGIKIPIVPGILPVTNFKQVQRIASMCKASIPPSFAETMNQNDS
PDWQFKVGIEHARRQTVDLIANEVPGLHYYVLNKSKAAEELLDGLELASAAT
>A0A2E1KLC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MSLTSVYHQRKVAISCELFPPKTAQGDESLLRNVAKLMERQPSFVTCTYGAGGSTRDKTL
DVVQAVKRDFSVPVAAHLTCVGSSVNQLRQYLRDAQARGVDHIVALRGDPPTGASAFQPV
KGGLRYANELVELIHREFPQFGVAVAGYPETHREAASSETDLQNLVRKVGAGADVILTQL
FYDNQAFFTFRDRCRQMGVTVPIVPGILPITSLAQIKRITSLCGASLPASLLDRFADSDE
PDWQYRVGVDFATEQVAELLRGGVPGIHFYVLNKSFATCEVLDRVIV
>A0A0D2T2P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium raimondii|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAIL
MNLGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDS
RNPSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGL
QPETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLD
KLDALVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFM
VWKDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A3A8G3F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter cumulans|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLADFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIKRFCEKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVQDLGLA
>A0A1E7J0V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium S5133MH4|TrEMBL
MKSGSSLERILESGQFAVTAEAGPPKGSSAKVIQRKGELLKFCCDALNVTDNQTAIVRMS
SLGGCLLLKELGVEPVLQMVVRDRNRLALQGDILGAAALGIRNVLCLSGDHQKFGNHPTA
KGVYDIDSIQFIQMVRTMRDEHKFLNGEEISGDVPFFIGAAANPFADPFEFRVIRLAKKV
NAGADFIQTQGIFDMARFTEWMKMARDKGLHEKTHILAGLIPVKSVGMARYMRNNVAGLS
VPLEIVDRMADAKDPKEEGVKICLETIEQLKEVEGVHGIHVMAVAWEDIVPRIVEEAGLI
PRPVV
>A0A507QQW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monascus purpureus|TrEMBL
MEKITEKIAALRPDASYFSLEFFPPKTQMGLANLQARLERMSQGLRPLFVTVTWGAGGTT
AARSLELAEICQRHLQLTTCLHLTCTNMSRALIDDALEEAKALGIRNILALRGDQPRSEE
YNMHGEDDSNKDFTYAVDLVRYIRQKYGDYFCIGVAAYPEGHPIESSDEAQSPEHDLPYL
IEKTEAGADFIMTQLTYDLDAYRRFENLLRNHESGIFKTIPIIPGLMPVHSYKVLTRVTK
LSNVHIPPKTLSKFDELKNDDDAVKSAGVDVLSGIVEGIKKIPCPVNRGFHFYTLNLEKT
VTFIIERCNLIPSVSELKDAEDSAIDSSTLDTLPDQEQLRSLARRRGSSINSQPQNRVIV
DKLQLTPDGLSKDVAAHETAALSAGVPALPPNRNMTLQISEGFGSLGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVTSSVARRLWGYPVSREDINTIFRRHVSGELYIVPWSEGGA
EEDGGGLNAETELIKPELLKLIDGRGWWTLASQPAANAVRSDHPIFGWGPQGDGFVFQKP
FVEFFCPSKDYKNILKSIFEKEGAQEKLAWLATNAAGEFESSHPSQSWDEVDLDANSSSV
NAVTWGVFRSKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSATERFIDEMKNDVW
LVCVVGQQFGAGTKPGSKEEEEEFKWMWKTLTGDDPIDH
>A0A2V6WPX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MAHAFSERLAAGPLLCDGAMGTLLYARGVPLDGCFDVLNLNTPALVQAIHSEYIAAGADC
IETNTFGANRFKLAVHGLGSQVREINLRGVKLARDVREAMGRDVLVLGSMGPLGKYLAPL
GTLGEGEARDAFREQAEGLLEGGVDAFVVETMSDLGEVALAVEAIRAVADLPIIAQVAFT
DEGLTFLGRTPAEVARTLSALPVQVVGANCSVGSSTLYEVLEQMRPAAGGRPIAIQPNAG
LPSRVGERLIYLSSPAYMADYAARMLAAGARVVGGCCGTTPEHIRAMRAVTGPTPSARAV
GRAAAPAAARPDQAPVLRAAAPPTRLERKLAAGEFVVTVELDPPRGHNIEKLVQGAKLLK
ERGAEIVDINDGSLGRIRMAVLPTAVLVRDATGLEINMHFTCRDRNLMGIQADLLGAHAL
DVRNILAMTGDPPRAGDYVNATAVFDVDAVGLLRILRRMNEGLDATGSSIGEPTAFCVGA
VLNPAAREPELEVERLRQKLEAGAQWVQTQPIYDLALLDDFLRRAGSPEVPVLVGVMPLH
SARHAEFLHNEVPGITIPPEVRARMREAGDKGLAVGIELAQGILRQARRRYAGAYLMPSF
GRYEVVAEVLDALR
>A0A7V3XGK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MSHAFSRRLAETPLLCDGAMGTLLYARGVAMDACFDVLNLTEPKLVQSVHADYIAAGADC
IETNTFGANRFKLAVHGRAGDVRAINLRGAKLARDVRESAGRDVFVLGSMGPLGKYLAPL
GTVTPDEARAAFREQAEALLEGGVDAFVVETFSDLVEIGLAIAAIRSVTDLPIVAQMAFT
DECVTFTGRQPGEVARVLRGHGVQALGANCSVGSSTLYEVLEQMAPEAGGVPLSVQPNAG
LPSRIGERLMYLSSPGYMAEYAARMLETGARLVGGCCGTTPQHIAAMREALDRHAPVRRT
ARPAIAVRPREAVEAPGLRAAPPPTLLGRKLEAREFVVTVELDPPRGHTVDKLIQGAKLL
KDRGVEIVDINDGSLGRVRMAVLPTAILVRESAGLDINMHFTCRDRNLMGIQADLLGAHA
LGIRNILAMTGDPPRVGDYVNATAVFDVDAIGLMEILRRMNEGQDATGNSIGDPTAFCYG
AALDPAAQDPAREIDRLHRKVEAGARWVQTQPVYDLESLDRFLARAGGCPVPVLVGVLPL
HSFRHAEFLHNEVPGITIPDAVRARLREAGDGALRAGIEMAQRLVGDIRRWYAGAYLMPS
FGRFEVVAEVLDVLR
>A0A7V5AMW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium|TrEMBL
MALVESLRKKKFVITVEFQPPIGGEMSEMAKTTDRLKGRVDALTIPELKLEGIVADTIGT
CRFLREQKFEPILQTTCRDKNRIELQDYLLKAARAGVANILTFTQDYRITGDSLQEIMFF
HVDSGKLFSVIESLRQGHDVKGREIDLSTDFCVGSGIEVRWGKNVPDMQLKEIETLTELG
THYFLSTPVFDLDAFREFLKRIEPFKIPVIAELIVIRSAEMGLFLNKHVRDGLVPRHIIE
KLAKATDKEKASMEIVGNLIKGLKDLCEGVHLIPLGVEDRISKYLEAIKL
>K3WFD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Globisporangium ultimum (strain ATCC 200006 / CBS 805.95 / DAOM BR144)|TrEMBL
MGKIIDSILSTYQSQETTRPTVSFEFFPAKTHDGVFNLLNRVEEMGFSLQPTFVTLTWRS
AFKDEKLWLRIGAHIQKEFQLDVLLHLTCHLPKDTLKQILNNARAAGIRNILALRGDPPI
GAERWKPIPNGLNNAVDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNESRMLD
LERLKMKQDAGADFIITQFFFDVDIMLQWVKDCRDMGITIPILPGYLPIQNYNSFCKFTN
WCKTKVPPQVQLDLERIKNDDAAVRRYGTELAIQTCRKLMEAGIKSLHFYTMNLASTVTQ
VLDGLDLIPTRHQRDLPWQSTLRRTGSGNKIGSGEQVRPIFWSNRQSSYIARTSEWDDFP
NGRWGDRASPAYGELSEYYLAFKRPKANRKDLWGTPEKPQDVWQVFVKFIEGNVKQLPWC
EQALSLESSMIRENLKWVNSNGFLTINSQPRVNGAPSSDPSFGWGGDDGFVFQKAYVEFF
VSPRLLEKLVAVIKEYPQLSYHALNAKGDEHRNTPLHSVTAVTWGVFPGQEIIQPTVVDS
DSFAAWKDEAFELWKVQWASAYEPGSPSHNVIQEIYDSYFLVNIVDNDYANDDSDIFSIF
TRIITDDMSKDDLRTRVIELEAKNEKLHETLAKIKSIQDETAKDLSDTHRELAKQREENQ
LMKVQLRQLQAQMAFTTV
>A0A2V6QVL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFSRRLDAGPLLCDGAMGTMLYARGVSLDACFDVLNLHQPKVVQAIHADYIAAGADC
IETNTFGANRFKLAVHGLADRVREINTRGVRLARDVRESAGRDVFVLGSIGPLGKYLAPL
GTVTAEEARLAFREQAEALLEGGVDAFVVETFSDFAEIALALEAVRSITDLPIVAEMAFT
NEGVTFTGRSAVDVARSLAGRGVQALGANCSVGSSTLHEVLEQMLPAAGGIPLAVQPNAG
LPSRIDERLIYLSSPAYMAEYAGRMVDAGARLVGGCCGTTPQHIAAMREVLDRKTSVRRE
TRRPVVSVSTPAVREATGLRTLRAPTTLERRLRDREFVVTVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLATALLVREATGLDVNMHFTCRDRNLMGIQADLLGAY
ALDVRNILAMTGDPPRAGDYADATAVFDVDGIGLIEIIRRMNEGLDATGASIGEPTSFFV
GAALNPAAAEVGREVERFHRKLEAGARWVQTQPVYDLAALDSFLERAGGSPQPVLVGVLP
LHSFRHAEFLHNEVPGISIPEPVRRRLKDAGDGALRVGIEMAQELVREVRGRYAGAYLMP
SFGRFEVVAEVLDAMH
>A0A2V6QFR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFSERLAEGPVLCDGAMGTMLYARGVPLDGCFDVLNLNNLRVVQAVHADYIAAGADA
IETNTFGANRFKLAVHGVEAQVREINRRGARLARDVRESAGRDVWVLGSIGPLGKYLEPL
GAVTADEAREAFREQAEALLEGGVDAFVVETFSDLAEIALAVGAIRAITDLPVIAQMAFT
DEGVTFMGRPPAEVARTLRALGAQALGANCSVGSSTLYDVLERMVPEAGGLPLAIQPNAG
LPSRIGERLIYLSSPAYMADYAGRMVDAGARLVGGCCGTTPQHTAAMRATLDRLLPGPRR
VAARAPATTRPAVAETSGIARTLPPTPLQRRLAAREFVVTVELDPPRGHTVDKLVQGAKL
LKEKGVEIVDINDGSLGRVRMSVLATALLIRDHTGLDINMHFTCRDRNLMGIQADLLGAH
ALDIRNILAMTGDPPRTGDYANATAVFDVDGVGLIGILRRMNEGLDATGSSIGDPTAFCI
GAALNPAAEDPDRELERMHRKIEAGASWLQTQPVYDLEALERFLARAGRIPVPVLVGILP
LHSSRHAEFLHNEVPGITVPDAVRARLRDAGESALRAGIEMAQALVAEVRRRHAGAYLMP
SFGRFEVVAEVLDALH
>A0A353V6C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MATRRDTPFREAMRSLLVFDGAMGSLLYERGVFVTQNFEQLNVTRSDIVRKIHDDYVAAG
AQVIETNTFGANRFRLDRHGLADQVRAFNVAGARLARQAAGETVWVGGSMGPSGLVPGVA
TQAELALVSATFAEQAAALVEGGADVLVLETFRHLAEIRLALEAAREAAPDTPVIASMTF
DPTGTVADGSTPEQVASTLRDLGADAIGVNCGDGPQLALAIAERLVRSGLPLCVQPNAGL
PRNVDGRLLYMATPEYFDVFLRRTVQLGATMIGGCCGTTPEHVRWMAKSARMLGDRRVEV
VPVGAVTTAEAFAGLTPTPLAERSAFAAKVAAGRFVVSVEVNPAPGLDPSKALEGAKMLI
DSGVDIVNVADGPRAMARMSNLAFCALLLVRYGIQPILHVCGRDRNLLAQIAHLLGAHAI
GIRNLVIITGDPPKVGDYPEATAVYDLDSIGLLHVASSANRGVDPAGKPLPGGKTAFLLA
TGFEPGAADLDREIQRLEKKKTAGAELVMTQPIFQQDLLDTVLRRIAHLELPVMVGVLPL
VSYKNAEFLHNEVPGMQIPEEIRERMRRTPGGEAARKEGVRIAREMLFAVRDRVQGAYLM
PPLGRYELALEVLEGLTV
>A0A2V6PZY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFDRRLAEGPLLCDGAMGTLLYSRGVAVDACFDLLNLNNPALVQSIHADYIAAGADA
IETNTFGANRFKLGAYSLEQQVREINRRAVRLARDVRESMGRDVLVLGAIGPLGKYLAPL
GTLTHKEARDAFHEQAEALLEGGVDAFILETFPGLTELRLAIEVVRAITDLPIIAQMAFT
DEALTYTGRTPAEVAAALAKLSVQAIGANCSVGSSVLYEVLEQMQHEARGLALSIQPNAG
LPTRIGERLIYLSSPPYMADWAARMVGAGARILGGCCGTTPAHIAAMREALGRKASPERR
PSRPVVSVRTREPLEAPVGEKPPPPTVLQHKLAAGEFVVTVELDPPRGHTVDKLVHGAKL
LGERGVEIVDINDGSLGRVRMAVLPTALLVREATGLDVSMHFTCRDRNLMGIQAELLAAH
ALGIRNILAMTGDPPRAGDYANATAVFDVDGVGMIEIIRRMNEGADATGNSIGGPTHFHV
GAALNPAAEDVDREIERLRRKVAAGARWLQTQPVYDLELLERFLARAGDVPAPIIVGVLP
LHSSRHAEFLHNEVPGITIPDQVRARLREAGDGALRAGIAMAQELVHQIRPRYAGAYLMP
SFGRFEVVAEVLDALR
>A0A5E5BQ69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea bronchicola|TrEMBL
MSDSLDNKTIMTQPSFSFEFFPPKTADGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQG
TLDAVIEIQREGVEAAPHLSCVGSTKENIRDILKTYRDNGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGEWFHIEVAAYPEYHPQAKSPRLDLEHFANKVKAGANAAITQYFF
NADAYFRFVEDASRLGVDVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
EAIRAFGLDVVTALCERLLAGGAPGLHFYTLNAASATKAMWQRLGL
>A0A2I8NPB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leclercia sp. LSNIH1|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPHWMAKMYE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A285L0U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. CC120223-11|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKGVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCASTGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A0A1YKZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas taeanensis MS-3|TrEMBL
MSQERRYSFEFFPAKTEAGHEKLLGTARQLATYKPDFFSCTYGAGGSTRDRTLKTVLQLD
GEVKIPTAPHLSCVGDSKAELRELLGLYKNAGIQRIVALRGDLPSGMGLASGELRYANEL
VSFIREETGEHFHIEIAAYPEMHPQAHNFEADLANFVRKAKAGASSAMTQYFFNADSYFY
FVERVQKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWMRKQLESYGDDSESIRAYG
EQMISEMCERLLQGGAPGLHFYTMNQAEPSLAIWNNLKLPR
>A0A257N845|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium NSP1-2|TrEMBL
MQSQHPQLFSFEFYPPKTEEGAVSLQAVHKKLATLNPDFFSVTFGAGGSTRDKTFDTVVD
IQAQGIAAAPHLSCVASTRDNIRAILKSYQQHGIAKIVALRGDLPSGMMSAGEFRYANEL
VEFIRLETDDYFDIHVAAYPEVHPQATSGVEDFKNFKRKVEAGANAAITQYFYNADAYFY
FVDLCEKNGIDIPIVPGIMPITQYSQLFRFSEMCGADIPRWLRKRLESFGDDKVAVQDFG
LDVVSRLCQRLLDGGAPGLHFYTMNQSAPTLAILENLQIKA
>A0A0K8J2R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbinix luporum|TrEMBL
MEIASLFQKKKVVFSLEIFPPKKTSSIDTIYKTLDDLKELQPDFISVTYGAGGNAADNST
CDIASTILNTYGIVPLAHLTCVNNTKEEIGLILDRLKENGVKNILALRGDINPDIPAKKE
FSYASELVQYIKNRGEFYISGACYPEGHVEAENIEKDIENLKIKVDAGVGHLISQLFFDN
DLFYNFLEKVRKAGVKVPIQAGIMPVINKAQIERMVTLCGASLPSKFTKMMQRFEHSPEA
IREAGIAYAVDQIVDLISQGVDGIHLYTMNNPYVARRISESIKGIINA
>A0A8J9T1M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. CECT 9288|TrEMBL
MKVTQHIEKAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNGLLDKKLTRMRPGTLGICASITHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGINN
VMALRGDAMKDEQSFVPKVGGNHFAIDLVQQIKLLNEGKYLHEVMHVDNKADFCIGVAGY
PEKHLESPSLLSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PLAVQRHLQILPQIFRIDLPEDLIDAVDKCKTNADVKQVGIEWAIQQSRELKAAGVPVLH
YYSMGKSENIRQIASQLF
>A0A268P4J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus clausii|TrEMBL
MELRDKLKTSLIVGDGAMGTLLYEQGFDLCYEELNLSQPDAVYHVHRSYIEAGAKLLQTN
TYAANAVKLKKYGLNESVADINSAAVGIAKKAIGNNEQLALVGTIGGIRGFLHEDTENKV
ITAALLEQITALLEAGVDGLLFETFYDFEEAKEAVALARRLTDKAIIMNVSMGDIGVLNG
GIPLGEALEQLHELGADVLGINCRMGPYHMLRSLEQLELSSAFPLACYPNASLPGYRDGR
FVYASNTDYFYEMTGAFIEQGVHLIGGCCGTTPAHIAAIAKAVETNTPKTRSLIVRRPSQ
LQEEGPGRGERLNEPLDQLARRKQTIIVELDPPKKLTIAKFMEGAKALKEAGVDALTLAD
NSLANPRVDNQTLAMLVREQLGLRSLVHLTCRDRNLIGMQSHLMGLHLAELHDLLVITGD
PSKIGDFPGATSVYDVSSLKLLPLIKQMNEGISFSGNSLGSKATFSTAAAFNPHVKHLDK
AVRRLEKKIEAGADYFLTQPIFDEQQFEQLYDATKHLPVPIFVGIMPLTSSRNAEFLHNE
VPGMTLSDETRARMAACGNDKEKAEQEGLQIAMELADAASAYFNGLYLVTPFLRYELTAA
LATHCRAIANPINHTMEGERI
>A0A7Y6VRG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CAI-17|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVTAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A6I6JP85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio cashew|TrEMBL
MHVCDLIEEHSPFISLEFFPPKEKEAWSGFFEVVEKVKALNPLFASVTYGAGGGTQDNTL
EIASRIKKDHGIEPVTHLTSVGASSEKLDGFLKSLREADIQNVLALRGDAPQGVKDFDFA
TQEFQHATDVIEFIRTRYPEICVGGAAYPEPHPESPSIQSDLEMVRLKVEKGARFLVTQL
FFDNRMYFDYIERLKELGADVPVIPGVLPIMSLRSAKFILGLCGAAIPGKFLSALEKAHV
EGGDEAVYELGIAYATKQAQELIDGGAPGVHLYTLNRAEAVLEIGKNLKI
>A0A6N7LP61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sediminis|TrEMBL
MKRISFEFFPPKTDEGKTKLLATQKKLLVKNPEFFSCTFGAGGSTRDNTRDMVNKLREQH
GDTAPHLSCIGQSKDEILELVNGYKESGVTRIVALRGDLPSGMGYAQSEIKYADQLVTLI
REETGDHFSLEVAAYPEMHPEARSFEDDIAHFKRKIDAGANSGLTQYFYNADSYGYYMDA
LQKQGCDAPVYPGIMPILNVANLLRFSGNCGADVPRWLQSKLNDIKDDDAAVKAFGEEVV
TRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGL
>A0A8B9ZH18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anas platyrhynchos|TrEMBL
WPRDSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDRWFSLEFFPPR
TANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHM
TCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVKHIRNEFDD
YFDICVAGYPKGHPEAESYESDLKHLKEKVLAGFMKDCQAIGITCPIIPGIFPIQGYHSL
RQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNR
EVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFP
NGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTCEESVFEVFTCYISGEPNK
NGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGG
YVFQKAYLEFFTSNEIVTALLKVLKKYESRVNYHIVNVKGQNITNAPDLQPNAVTWGIFP
GREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDND
FPLENCLWQVVDDTFELLNSPTQQ
>A0A7S6UGU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. H21R20|TrEMBL
MTATATSFEFYPPKTDEQRKQLDRTAARLKSAVPDYVSVTFGAGGSTLSHTPETIERLQR
HHALEAAPHISCMGGSREEIRAQLQRYISMGATRLVTLRGDLPSGMASPGDLRYASELVE
FIRDETGDHFRIEVAAYPEMHPQARDAHADLKHFIGKAKAGADGAITQYFYNADAYFRFV
DDVRAAGVDIPIVPGIMPIANFSQLRRFSEMCGAEIPRWVTQRMLAYGDDVASVRAFGTD
VVAQLCQRLIDGGAPGMHFYTLNLARPTLAVLARLA
>A0A1H5WNB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jhaorihella thermophila|TrEMBL
MTIPAVSFEFFPPQNLAGSFRLWDTVQTLAPLGPRFVSVTYGAGGSTRELTREAVQTIHD
HSGLNVAAHLTCVNATRAETLQIAESFARAGVTEIVALRGDPPKGQGRFTPHPDGFANSV
ELVEALAATGHFTIRVGAYPDTHPEAASTQADIDWLKRKLDAGASEALTQFFFEAETFLR
FRDACEKAGIDGARITPGILPIENWKGARNFAHRCGANVPHWLEDAFDKALRDGREDLLA
VVVCSELCSDLIDEGVERLHFYTLNRPELTRDVCHALGVTPRVQLQNVA
>A0A435IS86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.001.04.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>D4DDN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton verrucosum (strain HKI 0517)|TrEMBL
MEKISDKINALPKDAHYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEETKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFNYAVDLVRYIRKKYGDYFCIGVAGYPEGHADESHPEVQDPLKDLPHL
IEKTQAGADFIMTQLTYDIDAYKKYEALLRNHESGTFKTIPIIPGLMPIQSYHTLTRVTK
LSHAKIPPQILAKVEACKADDEAVKRVGVDIVSDLVEDIKKIATPGHRGFHFYTLNLEKS
VSFILERCNLIPPSSEAPSDSELEFESAVYAASGASNGVATPDGRSTNVNRLRASSMNSQ
PHNRVIVDRLTRASDRSERSSTVHETSAQTAGYPALNPPNRNTALQISEGLGSLGREATW
DDFPNGRWGDARSPAFGEIDGYGPSLHVTAQVARKLWGTPTSRDDISKIFKRLLSGELHA
VPWSEGGAGEEGGLNPETATIKAELLKLVEGRGWWTLASQPAVNGVRNDHPVFGWGPRGE
GFVFQKAFVEFFCSGDDFHSKLKPLLQSYGHDEFAWFATNAKGDFQSSTSPETPTQPPTD
PTEAPFDADPLTEMDNGSVNAVTWGVFRGKEIVTPTIIEAVSFRAWGEEAFGIWEEWRRV
FPRGSPSEKLIREIKDDVWLVCVVDQRFGAGGDVGKESNEEDGKLLWKVLAGEQTK
>A0A0J6S836|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium variabile|TrEMBL
MITTAFRPSRESRRPIRVSFEFFPPKSAEMEATLWSSIERLAPLGPSFVSVTYGAGGSTR
ERTHNTVARLVRETDLKPAAHLTCVAATKGEVDDVVRAYHEAGVRHIVALRGDPVEGVGS
AYTAHPGGYERSCDLVAGIKRVGDFEVSVSAYPERHPEAGSLDQDLDALKAKVDCGADRA
ITQFFFDNDLFFRYLDRVQSRGINIPIIPGILPVQNFKQAANFARRTGASVPDWLAARFE
GLEDDVATRKLVAAAVAAEQVLDLVDRGITDFHFYTMNRADLVYAICHLLGLRAAPAVTE
KAAA
>A0A5M6CQ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Taibaiella lutea|TrEMBL
MKITEHIAQAKETLISFEILPPVKGKSIDNIFSNLDPLMEFKPSFINVTYHRAEQIFKKR
EDGTFNRVEIRKRPGTVGICAALMNRYRVDAVPHLICGGFAKEETENALIDLHYLGVDNV
LALRGDSPANEKFFSAHPQGHRYAVELVDQVVKLNKGKYLEEDIVDAGKTDFCIGVAGYP
EKHFEAANMELDLHFLQQKIEAGANYITTQMFFDNKKYTSYVEKCREANIHVPVIPGLKP
ITSKRQLSILPSIFHVDIPHELAIEMLKCKTDEACEQVGTEWLIAQCRELLAQKVPVLHF
YTLGKPNVIYNVVKAIL
>A0A0D3LNF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flammeovirgaceae bacterium 311|TrEMBL
MKITEHLSRAEKTLFSFEVLPPLRGQSIHSLYEHMNPLMEFNPPFVDVTYHREEYVYKKR
ENGLLEKVSVRKRPGTVGICAAIKNRYNVDAVPHIICGGFTKSETENALIDLDYLGIDNV
LVLRGDPIKSEARFVPEAEGHHYAIDLVRQVKCMNKGIYLHEEMENSAPSNFCIGIAGYP
EKHEEAPNLLADVRHLKAKVEAGADYVVTQMFFDNSKFIRFVEMCREAGITVPIIPGLKP
ITVKRQLAVLPKIFHIDIPEELLIELENCKNDAAAKQIGIEWAIKQSKELMEWGVPCLHY
YSMGKSDSVYSIAKEMF
>A0A4P5TZ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilaceae bacterium|TrEMBL
MPKKISYSFEFFPPNTPEGIKNLADTRQQLSAFNPEFYSVTFGAGGSTRDRTLETVLEIK
QEGFNAVPHISGISSTKAEIKTLLDLYQQNDIKHLVVLRGDVPHGPVSRGEFKHANELVS
FIRQETNDYFHIEVGAYPEYHPEAASSQTDIQNFKNKVDAGADSAITQFFFNADAYFRFM
DECLIADIDIPIVPGVMPIYNIKQLARFASNCGAEIPRWLRIKLESYGDDLPSLRSYGVD
VVSELCETLIEWDVPSLHFYTLNQAGIISRIIQNIEST
>A0A0T9R3N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia similis|TrEMBL
MERKLSFEMNSAKNEKEMEIIFKLIEFTNTLDPIYYTVNTEIGASVWSDTYRTIMELREK
TDVTLIPHITINNKKEREIMQIIEQYIKVGICEFFVIRGDKHVYDQDNPINYGVELIELI
RCSHKTVGIKTSLYPDFHKETTDVKEEMDWNERKYQLGVNEFISQLTLNTNALDFLSHWV
DKERTFTPSIMPLGNFSFIEKFTSSNSIDYPLWIKKFANSKSNSNEDKENIGIEIIRFLC
REHLHKRERLHVFTLNKVDVMKKIFQ
>A0A7Z0GMN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nesterenkonia xinjiangensis|TrEMBL
MPVSTPSPGAVRLTPPATSDPSHTTSVLVQRTRRRSLISFEVFPPRPATAGRDPWRSIEL
MAEAAPDYFSVTHGHNQPEGANVEVIRHLLRTTPSPVMAHLICAGSTSSQLRGSITELLD
LGVRDILALRGDPPDGGKEWIHQPGGLNRAAEVVELVREVEQERLSPPEGPGARPVSVSV
AAYPPSGTDRDHAADLHALWEKQEAGADYAVTQVFYDPEDYAQLVDSARSQGIHLPIVAG
IAPLTSPRRLRRLEEITGVPVPRHLVDYLDVDDAAERRRRGVAATLNLIDTVLELGCPGL
HLFTFNQHPPALAILDHLRIRDAARRQRNIFDAG
>A0A7N6AYJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabas testudineus|TrEMBL
MVNQVQRGGGSWQSCKSDSSGASNSGGESSKESSRCSTPVLDADRLDRLRDKMRRRMESG
DRWFSLEFFPPRTAGGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKISGHLAKAKHLGLKNIMALRGDPIGSDWEEEEGGFNYAV
DLVKHIRSEFDDYFDICVAGYPTGHPEAQSYDEDLQHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRANGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGRVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLQMWGEELMNEESVYEVFTCYITGQPNRSGHKVMCLPWNDEPLAPETNLLNDELEKVNR
RGVLTINSQPNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSSENVDALLQVLKKYEPRV
NYHMVNVHGRNMTNATDLQPNAVTWGIFPGREILQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWQVISDMFELLDSLTQNTF
>A0A6H1LFB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. RLB1-33|TrEMBL
MAPLLDDFSLEMTGKDVPKLEEARGTIPQGTRINVTFLGNEDLDMRLAAARAVKRLGFVP
VPHISARRLPSRAALEEFLAALEADGLADNVFVVGGDPVEPHGPYDDALALIRSGLLQKH
GVRHVGVSGYPEGHPAIADPVLWSAMEHKSAALEEHGLPGAVITQFGFDVDAVLAWVEAV
RARGIYLPVRIGVPGPAGIRRLMTYAARFGVGTSASIARKYGFSLTNLMGTAGPDRFIRA
LAKGYDGRRHGELKLHFYTFGGLKTTSEWVADFRDEEN
>A0A1V3SUL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospirillum ferriphilum|TrEMBL
MTFREALNAREFLVTAECSPPKGTRIDGLLDRLTPLKNRIHGINVTDNQTGVMRMCPMAM
GLHLKGIGLDPIIQITLRDRNRLAIQSDLLGMSSLGLSQVLCLTGDPPKLGDHPEAKPVF
DIPTQELIRAITLLNGGTDLSGKDLNGKTDILPGAACSPEGDQETEFRKFEEKFDAGARF
FQTQAVFSPEKMEEFMRFASPFSVPVIAGIILLKSAKMARYLNDHVPGITVPPPLIERLD
KCPPGQALESGIAIAAETIRAIRPLVHGVHIMTVGAEETIPRILDQAFG
>A0A220RZU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria chenwenguii|TrEMBL
MSYAREINELNNSLADLNGGINVSFEFFPPKNEQMEHMLWESIDRLKVLQPKFVSVTYGA
NSGERERTHSIVKSIKQNTGLDAAPHLTGIDASPEELKAIARDYWDNGIRRIVALRGDEP
PGYAKKPFYAADLVALLRSVADFDIAVAAYPEVHPEAKSAQSDLINLKRKVDAGAGHVIT
QFFFDVESYLRFRDRCVMVGIDAEIIPGILPVTNFKQLGRMAQVTNVKIPNWLARMYDGL
DNDPATRNLVAASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPSENPADCK
>A0A2L2XV36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis sp. 0824|TrEMBL
MTTRLQRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSRSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQEVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDMAGIPPIHN
>A0A1X7DZ37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. URMO17WK12:I5|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDTKDELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEVDLGNFVHKVKAGADSAITQYFFNADSYFY
FVERAQKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLAIWNNLKLPR
>W0E206|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marichromatium purpuratum 984|TrEMBL
MSPQDPTPTYSLELFPPKTAERMERLKSEIATLNTVSPRYFSVTYGAGGSTRKGTFETVS
WLRSQGIDTAPHLACIGSPRAEVEELLGHYREQGIDRLVALRGDLPSGMGGGIGGDFRYA
NELVEFIRARTGDHFRIEVAAYPEYHPQSGTPDRDLANFKRKVEAGADAAITQYFYNADA
YFAFIERCQAVGIDIPIVPGIMPITNHSQLARFSDACGAEIPRWIRRRLEGFGDDLASTR
EFGHEVVLQLCRRLIEGGAPGLHFYTMNQSGPTLRLWQELGLPSGD
>A0A5D3YKW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fodinibius salinus|TrEMBL
MKVIEHYDQADEPLISFEIIPPKRGGSVDKVFRSLDKVMKYNPPFIDVTYHAAESYYEEL
GDGTVKRHIKRKRPGTIGLCAAIKHKYDVDPVPHLICEGFTKEETEDALIELNYLGIDNV
LTVRGDSPDDSVPRYKNGTFNNYALNLVEQVADMNRGQYLEDIVNAQETDFCVGVAGYPE
KHFEAPNLDFDIQQLKKKVDAGGDYIVTQMFFDNEAYFNFVEKCREAGIECPIVPGLKVL
TRERHLNFLPKYFHLNIPEELSEEVQADVDNVREIGIEWAAQQCTELLEGGVPGIHFYIM
GDPTPALDAIDKLPLGHEVASR
>A0A5J6FHN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces nitrosporeus|TrEMBL
MEPPPCRTPAGPPPPGSGAPYAFSFEFFPARTEAGERALWQAIRRAEPLSPAFVSVTYGA
GGSSKARTVEVARRIAAETTLRPVAHLTAVGHSVAELRGIVGRYADAGVRDVLVLRGDPP
GNPRGEWTPHPQGLRHAYELVELVRSLGNFTIGVAAFPERHPRSPDWDSDIRHFVAKCRA
GADYAITQMFFDVEDYLRLRDRVTAAGCDIPLIPEIMPATGIRQAARFAELSGAVFPAGL
ARRLEAAGDDRDASYRIGVEHATAMGRRLLAEGAPGLHHITLNRSGAAFDVHHGVLGAGE
ETLVPPPARAARAVPGPPSAATGPRPW
>A0A2T0X699|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hasllibacter halocynthiae|TrEMBL
MPSPTLSLEVFPPRGAGAVRRLDGAMDRLEAIPLGHVSVTWGAGGSTSEASVETVRRIAG
RGHDVLAHLTCGGQSKAETAEAIGALRDAGASAFLALRGDAEDMEGPFEPHPEGHGGSLS
LIRALREAGETDIRVAAYPNPHPDSRGREADLDHLRAKADAGARIAVTQFAFEAEPILRL
RDRIAAAGIPLELHAGLLPIHDWAKVARFARACGLAPPPEMDEGFRAAARDGRADLYATA
IGTEQADALMGGGIEHIHLYAMNRAGPTLRVAEAMGWIPALAAVA
>A0A086Y475|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenirhodobacter enshiensis|TrEMBL
MPNVSFEFFPPQSLEASFRLWETAQALAPLKPGFVSVTYGAGGTTRKLTHEAVAAIHKNY
GLNVAAHLTCVNASRAETMDIVNAYHDAGVTEIVALRGDPPKGSAGFEPHPEGFASSVEL
IEALAADGRFTIRCGAYPEPHPEAKTPLDDVRWLKRKTDAGATSAITQFFFEADTYFRFR
DACAAEGVRAPIIPGILPIQSWKGAKAFAARCGAHVPAEIAEGFEKAVAEGREAEHAVAV
CAALCERLVAGGVEDLHFYTLNRPDMTLAVCDAIGLKLPDTCGCASSAA
>A0A1J9Q8R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emergomyces pasteurianus Ep9510|TrEMBL
MHIKEKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFVDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCEDQDDPDLLMQHLKEKVDAGGTF
IITQMFYDVDNFLDWVNKCRDNGIKVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEAL
EPVKNDDAAVRNMGKSLVAQMCKKMLAAGIHHLHFYTMNLQQATKMVLDELGLIPSHQTP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSLKELSDIFVRFLNGNLDRLPWSEGAVTEETEVIKPDLLD
LNERGFLTINSQPAIDGIPSSHPVYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNS
DLTYYCVNKNGELKTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHPATSPSRHLIQQVMDSWYLVNIVNNDFHKTHDIFNLFKDLKVKDLDTEVEAIAPAAE
PVDNTHLNGQSPEKHFNGSSTEATESEQKLNSN
>A0A5J6FF01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces nitrosporeus|TrEMBL
MALGTASTWTDHARTVREMLASGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPTFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVDHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSDGWDADIRHFVD
KCRAGADYAITQMFFQPESYLQMRDRVVAAGCETPVIPEVMPLTSVRQLERFAKLSNASL
PSSLKDRILAAEDDPAAVRSIGIEFATEFCAKLLAEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A829NT28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ruminococcus] gnavus CC55_001C|TrEMBL
MKIIDRLREDGIHISFEIFPPKTDAGYDKVIRAAEEMAGLKPEFISVTYGAGGGTSKNTA
KIASYIKHDLHVESLAHLTCASSTKDEVRSVIASLKEQGIENILALRGDISEDMVFPSED
RFHYAYQLVEEIRRHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSARQMKRSCELSGTVFPRRFQAILDRFGDSPK
AMEQAGIAYATDQIIDLLANGVKNIHIYSMNRPEVAAAIMHNISEIIQC
>V9WAB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus larvae subsp. larvae DSM 25430|TrEMBL
MRPDLRLALQHQLLTGDGAMGTYLYQLGFPVGISYEELNLLQPQVIADIHRRYYEAGAKI
IETNTFSANKEKLSKFGLEQEVKRINRAGADLARQTVGDDAYVMGAVGSIRGSKRKNVLE
ADVRIAFHEQVEALLEASVDGLLLETFYDLDELLIALRLIRNLSDLPVICQFTTEGNHTT
HDGIPLQEAFERLKDEGADVVGFNCVSGPNGIMQSIGRIHPLEQVPFSVYPNAGIPDYVD
GRIVFGATPEYFAETALRFADLGARIIGGCCGTTPEHIAAISKALRGYVPSAEQAFRLRG
TETGRDEEHPVISTGTAETGDSSYMDGVQNLVDLVKQRPTVIVELDPPRTLDINKFMVGA
KALKDARVDAITMADNSLAVTRMSNLALGALVQQRLNVRPLVHIACRDRNSIGTQSHLMG
MDALGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNKGLAFSGKPLKKKARF
VIGAAFNPNVKYLEKAVQRLEKKIAAGADYIMTQPVYDHALIERIHESTKHMDVPIFLGI
MPLASGRNAEYLHNEVPGIQLPDETRGRMAGLEGEAGRAAGTEMAKELIDTALQYFNGIY
LMTPFLFYDMSVALTEYIWGKTSSRHPLLSRV
>A0A7C9R607|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium zhangyense|TrEMBL
MSNYGFSRRSDIGDKIRVSFEFFPPKTDEMEVRLWDTVKRLEPLQPNFVSVTYGAGGSTR
ERTGRTIKRIQGETNIQAAAHLTCVGASKDEVNAVIAEFVSYGIKRFVALRGDPASGVGG
TYRPHSEGYQNGADLVAGLKSFGDFDISVAAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFASRAGAHVPAWLAERFE
GLDRDPQTHALVAAAVAAEQVLDLVERGVGDFHFYTMNRSDLVVAICHMIGIRAPAETVV
DVAGSAAA
>A0A3Q9IGH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. FWC26|TrEMBL
MTLPPTRRVIGPVARAGERTGRPRVSFEFFPPKTPQMEESLWAAITRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILDETRLKPAAHLTCVGASRDEVDDVIREYWETGVRHIVSLRGD
PPPGEGGIGGVYVPRADGYANATELTKAVRGIAPFEVLVGVYPEKHPESPSLEHDIDVLK
QKVDAGATLGISQFFFDLDAFLRYVDKVRAAGITIPIVPGIMPVTNFAGLKKMAAACQTA
IPAWLGNLFDGLENDAETRRLIACSVAAEMCAKLQEQGFEDFHFYTLNRADLVYAICRVL
GVREVSPATSEVAA
>A0A0F2NHY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium BRH_c4a|TrEMBL
MQRILDSGQFAVTAEIGPPKHASAHGVRHHAEMLVNHVDATNITDCQTAIVRMSSIAAGV
HILDCGIEPIVQMTCRDRNRIAMQSDLLGAYSLGMRNVLCLSGDHQKFGNHPSSKNVYDV
DSMQLIQLLARMRDEKKFFSGEEFKDHEPKFYIGAVANPFADPFEFRVDRLEKKVEAGAQ
FIQTQCIFDMERFERFMEMVRERGIDQRTHILAGITPLKGWRAAKYLQTGVSGMLVPDSL
VERLKGAQDPKREGIEVAIEQINYIREKVKGVHGVHVMAIAWEEVVPEIVERTGLFPRPK
FED
>G0RUZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypocrea jecorina (strain QM6a)|TrEMBL
MDRITDKIAALPADAEYFSLEFFPPKTQMGFSNLRVRLQRMERALRPLFVNVTWGAGGST
AQKSLELAELCQRELGLTTCLHLTCTNMSQALIDQALDDARALGIRNILALRGDPPRAEY
RDADEPTEASEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPYL
VDKVQAGADFIMTQLFFDIEAYEKFETTLRNHPSGAFKTIPILPGLMPIQSYAMIKRTTK
LSHAKMPDAIMDRLNAVKGDDEKVKMVGVDILSELVEQIREIKSRTPGPKGFHFYTLNLE
KSVSFILERTKLIPDIPDEEEAIADESPAVAAVQRMIPKISVNGNVPPRAPSHTRTARRQ
SSVGSDPHNRVIVGRAATHPEWEASSTEAGIPAGSVNTRANTLAISEGEGALGREATWDD
FPNGRFGDARSPAYGEIDGYGVSLHMSVTQAVRLWGYPKVASDINDIFVRHIRGEISAIP
WSEEDLLPESSIIKDKLEALNRKGWWTVASQPAVNGLPSSDPTFGWGPASGFVFQKSFVE
FFLPSADWKILYDKLTSAEVEEVVCFYATNAKGDFVSSDYTGGSARAGGSESTNAVTWGV
FPGKEIVTPTIIEEVSFRAWSEEAFGIWAEWAKVYGRGSDSQKLLDGIREDYWLVNIIHH
DYVDTDALWRLLIE
>A0A327JMS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobium orientis|TrEMBL
MSETETATDDTPERPEMHVSFEFFPPKSDKMEATLWQAIEKLAPLEPRFVSVTYGAGGST
RERTHATVARIVRETNLTPAAHLTCVDATREEVDQVARDYLAAGVRHIVALRGDPIAGIG
TSYRAHPGGYAYSSDLVAALKKIADFEISVSAYAERHPESPDWQTDIDMLKRKVDAGATR
AITQFFFNNDLFEAYVERVRAAGIFIPIVPGVIPIHNFTQISKFAGMCGASMPQALVERF
EGLEHDPETHKLVAAAVAAEQVDDLVSRGVTDFHFYTLNRADLVFAICHMLGIRPHMETV
AA
>A0A2S7F031|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hyacinthi|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKTYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQASDALSDLRHFKAKVEAGADGAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAHGDDADAIREFGADLV
AALCARLLAGGAPSLHFYTLNLAKPTTSVLSRLA
>A0A254N1Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelomonas puraquae|TrEMBL
MSTPVSFEFFPPNTPVGVEKLKAVVQQLGELSPQYFSVTYGAGGSTRDKTLSAVMDIAAA
GFEAAPHLSCVGSTRENIADILGTYRAQNIHRVVALRGDLPSGTATAGEFRYAAELVSFI
RETQGADWHIEVAAYPEVHPQQRYAAKDLQHFADKMKAGADGAITQFFFNADAYFHFVEE
ARKLGVTQPIVPGIMPFHNYARIAQFAQRDGIDIPRWVQLKMEGFMDDAASIRAFGLDVI
ARLCERLIDGGAPGIHFYTLNQAPLVLELCKRLGLGAKV
>A0R6T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)|TrEMBL
MLTDFSCAPFDEQDVVRTAGVLAGSCDAVLVGEHQNKPDFPPTLMGRLLLDALTGSGVTP
WITLSCRDRNRVVLEQELRGLRSIGADTVMCVTGDGRGYDVRPDVTQTFDLDGPRLVALA
ASLDMVAAVPETPTAPPVNARPRRLVEKQKAGAGIAVLNHVPYPHTVARFMESGRAAGLT
IPVIAAVAVFTDTASAAVLQGLPGLELDPAVTQRVLGAADPVEAGIEAAVEEARALLSID
GIEGVNISGSASASGGGAAIKAEVGRRVKNLCVDRTRGEAP
>K8EH17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bathycoccus prasinos|TrEMBL
MPPSFPTTGTFKLLSFNKPNAFISLERSPFLKWSAQSKAFETGKFSHVVHPNLPVFDDDS
DDVKGKSDRDIIPPRCVNIAEEERNAFGSEAKHVQTLSASMFHTEKQFKKQVEMVSFGCE
NVSHVLFVSGDEKKKELDALKMLKIATKMRRDGDIPDEIKFAVVANPNTENVSAEYLEEK
VAAGAELIITQPFFDYERCHEWVSSANRRGVLSTTNSGISNSNSASLVIGACAPSNRKDV
EFWAKLVYGDDQSAKILSSPSSPIAKLAREYEQKERELTTALYRDWIFERCELRAVAALG
HAASSGVHFMPVTRIGYDIQELEAIANLCGCTLPLKWVSIRSSFGGRSGDDDAHSSRSEN
EEEESTFNPIRLVYLPSDVVAEKIASRTSLVKYIVHLWGYGTNDEELKTSVRKGKDEAWL
DQSMTYKLTCCDFGATRSNEKSEVMRRLSNLVPGAFEPRSKVSLDQPRVEFLSMEVKSTV
QIDLGFQGVRMFFGRVVGKDKSRKHLNLLDLKKRRYLGPTSMEAHMSLIMCNMIKAERER
GGPVLDPFCGTGSVLLAAAELGCFTCGFEIDPRVLEFGKVDAKTGQKLDVITNFKDYGFN
KPIFLIRGDVHKSPLLKVVEDEVESRCRISGSNGGGEKFAPLDLEKIEKRIKQMEGAFQG
IVADPPYGIRERGRKSQFGGKRGKTEQDMINIGERFDNHIPSTVNYPLSEIMDDLMDLSA
KTLPVGGRTCFFLPADVQQTNPETDFPSHPCLRVVAHSLQNFSPTWGRRLVTYEKIEPFD
IHKHLENVRTREHLRRVLEQDVNYLDLTERVKKFVFADEKSNERKKIQRDIIRRACKEHR
EGVTLDRETILERRERAKSLKEKDQGLKNRGKKT
>A0A420EJ08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altericroceibacterium spongiae|TrEMBL
MSYATIHPDWEKPAANMVDGYSLEMTAKEMDHLREAAPLIRPGTPIAVTFLPGEEMEDRV
AAAKLVRELGFEPMPHLSARRLESTETLDNLLARVTGEAGVKRVFMIAGDPPKAEGPYED
SLQIIESGLLEKHGITVAGIGGHPEGHPNVSKSDLWVWMERKITALRERDITPLIVTQFA
FDDEAILNWIEEMRERGIDVPVRIGVPGPAGIKRLIGFAKRCGVGASANVMKKYGVSLTN
LIGKAGPDKLIHALESGLTPEHGRVRLHFYPFGNLKASAEWINEYNAKHS
>A0A7J0BQ59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio psychrotolerans|TrEMBL
MKIIDLMAARTSPFYSLEFFPPKERENWPGFFRTVERLKALDPLFASVTYGAGGSTQDNT
LEITAHIKNAIGIEPMAHLTCVGADGEKITDFLDKLRAAGVHNVLALRGDAPRGVEIDWN
TQAFRYASDLVTFVRDCCPDFGISVAGYPAAHPESLTFSDDLAYTKVKLDAGSDFVVTQL
FFDVREYFNFVAQLRAAGVNKPVLPGILPIQSLGSIRRILTLCGANIPGKLYLALEEANE
KGGDEAVKEAGLEFAVQQIRRLVDGGAPGIHLYTLNKADMCLEIAERAGL
>A0A7G2IMQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii|TrEMBL
MFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A846XXK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia vermiculata|TrEMBL
MSFDNVRGRSTPGRPSRTPQVSGTPSVVGQLGRRPDGTVPFSVEFNPPRDEAAEARLWRA
AREFERMHPAFVSMTYGAGGSTRDRTARITGQLARETTLLTVAHLTAVGHSVAELRSIVG
SYADAGIRNMLVLRGDPPGDPLGEWRKHPDGVEYAEELVRMVCELGDFHVGVASFPQGHY
RSPDLDHDTRYLVSKLRAGAEYSITQMFFDVEHYLRLRDRVAACDPEQGAKPIIPELMPI
TSLRTVQRAEELSGRALPESVMRRLDRAAGADPEANRAAVREVGIEIATEIAQRLIDEGA
PCLHFITLNFARATTEVLTNLGYTVTPAVVSA
>A0A7I8DIN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerocolumna chitinilytica|TrEMBL
MDLREYLKEHKLITDGAMGTYYSRLLNNDNAVSEFGNITEEETIVNIHKAYMKAGAALIR
TNTFAANRQTLGQTKEEQELLIKKAYQLAKRAVEEVLKEESFPGNTKAFKGNRQVYVACN
IGPIPENGTKPEEDILAEYQDICDVFLEEGGEVFLFETFSDFYYLKNLVKYIKEKKPEAF
IITDFCLNKNGFTSKGISARSILETIEETKEIEAGGFNCGIGSGHMYQILKKLTLPVGKF
IFAMPNAGYPEQFRNRLIFMDNEGYFRDNIQRICNLGVDAVGGCCGTTPDFIENMAEKLL
LDDTFRGDRKVLAGIKEAGIEVRTNEFYQNFQEKKKVVAVELDPPFDASDEAVIACALKL
KDTGTDMITMADSPMGRSRVDSVLMALKLHNETGLPVMPHICCRDKNMIAMRSMILGAYL
NGIRNLLVVTGDPIPSEHRQSTTGVFDYNSIQLMNYVKEMNREHFSGEPIYYGGALNYGR
GPIEKVIERIERKIEAGAKYFLTQPVFSEEDIRRLEVIRSKVDTKILCGIMPLVSYRNAN
FIKNEISGIHVPDWVIEKYRPDMSKEEAEWVGADIASCIIKDLSSFADGYYFMLPFNRVS
LMEKIKVQ
>A0A8B4QDM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kurthia zopfii|TrEMBL
MGLIEDLKTKVLTADGAMGTLLYSYGIDFCYEELNVRKPAVIEDIHRQYIEAGADVIQTN
TYTANTIKLSRYGIEEEYEILNKAAVEIAKKAVGDGPQYILGTIGGIRGIRKHEFSLEEI
LISLVLQAKVLVNSGVDGLLLETFYDLEELETLVKSIRKFTSIPIIAQVSMHDPGVLLNG
MNLNEAFERLEVAGADVVGLNCRFGPHHTIVALENVELPENAFLSAYPNASLLDLEEGKV
VYESEFEYFGKAALELRDEGVRLIGGCCGTTPDHIREVKRQLSNLQPVEDKVVEVRAVEP
IKEAAVRIYEPLHEKVKKGRSIIVELDTPRHLETEKFIEGAKILQQAGADAVTMADNSLA
SPRVSNIAMGSILKYEEEVRSLAHITCRDRNLIGLQSHLMGLDALGINDILAVTGDPTKV
GDFPGATSVYDVSSIELLQLIKKLNEGISFSGKPLRKKASFSVAAAFNPNVRVVARAVPR
LEKKIAAGADYFITQPVYSKEKIIEIYEATKHLDTPIYIGIMPLTSLRNSEFLHHEVPGI
KLSDEVLVRMAKADIDQVTAQAEGIKIAKELIDTASELFNGIYLITPFMRYDMSVELIEY
INQLDEQQVKGGVEYVKASH
>A0A507FAS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spizellomyces sp. 'palustris'|TrEMBL
MKITKKIEKALAEERCFWSFEYFPPKTETGVINLYDRMERMYALGPEFIDVTWNAGGSSS
DVTMQVCTTAQSVYGLETCMHLTCTNMPREKIDIALRDAKAAGIQNILALRGDPPRGQEN
WTKCETGFSYARDLVKYIKEEYGDYFCIGVAGYPEGHTENPDTEEDMRHLKAKVDAGANY
IVTQLFYDVNLFLDWAKQCRDIGIDIPILPGIMPIQSYGGFKRMTTLCKTFVPKEILDDL
EPIKDDDKAVKEYGVQLAVKMCNTMKDAGIRGFHFYTLNLERSTRLILEGLGFVAPIELA
RPLPWNPSLAKNREKENVRPIFWKNRTRSYILRTEAWDDFPNGRWGDARSPAFGEIDGYG
FNLKYPADECLQMWNHPQTEKDIFELFAKYCMNELNALPWSDSPLYPESDVIRTRLADIN
SKGFLTINSQPAVDGAPSTHPIYGWGPKNGFVYQKAYLEFFVSPEALDNIIAKVSSHPYV
TYYAVNKQGDLRTNTQGDSPNAVTWGVFPGQEIIQPTIVESVSFMAWKDEAFELWNKWAC
LYEPESQSAKMIQNIWDTWFLINIVDNNFKDEHAIFTIFDDGTTRPPASR
>A0A1H4AP57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. tc2-28|TrEMBL
MTVADYINQQTSDEHRFSFEVLPPLKGNGTEALFRTIDKLAVFNPAFINITTHHSEYVYK
ELDNGQFERQRIRRRPGTIAIASAIKQRYNIPVEPHVICSGQTIEQIEYELLDLQFLGIR
NLMLLRGDKAKEDSRFTPTPGGHAHTTDLIKQVVRFNEGFFADGTPIKHPGPKFDFGVAC
YPEKHEEAPNLERDMEYLKQKQDLGAQYAVTQLFYDNEKYFQFVEKARQMGITIPIIPGI
KPMAKLSQLTVVPKTFHCDIPEALAKEIVKCKTDEQAMQLGIEWTTQQCRELYAHGVHNI
HFYTVSAVDSVAEVARRLL
>A0A413I0B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. OF03-15BH|TrEMBL
MKMKELFDRGEFAVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNPLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A0N1LCR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. AAP35|TrEMBL
MMNAFRPSRHGSRRPKVSFEFFPPKSDEMEVALWESVRRLEPLGPSFVSVTYGAGGSTRE
RTHATVKRMVEETGFKPAAHLTCVSASRDEVDEVIRGYWEAGVRHVVALRGDPAGGLGTV
YEPHPQGYHQTSDLVAGLKRIGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAI
TQFFFDNDVYFRYLDKVRAAGIDIPILPGIVPVQNFKQTANFARKTGASVPQWLADRFEG
LEEDAATRRLVAAAVCAEQALDLIDRGVGDLHFYTMNKADLVYAICHLVGVKPEKAEPQA
AAAE
>A0A1V5X599|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium ADurb.Bin205|TrEMBL
MNFKEKLACGKFLLTSEVGPPKGVEIRSLLEESELIRNRVDAINVTDLQNSVMRLGSLAV
SSILKHHGFEPIYQLTCRDRNRLALQSDLLSAAVLGIENVLILTGDHTTAGDHPEAKPVF
DLDSVQLLQAADRLGQGFDIKGNRLSGKPPNFCLGAVVNPGADPLEPQIIKMEKKIAAGA
QFFQTQAVYDIKIFENFLKKTRHLKTKIMAGIVLLKSAGMAEYMNQNVAGVSVPEELIKK
MSEAEDKVKQSVKIASGIIKELKPMCEGIHIMPIGWGRFVPEVLDASGL
>E7RQP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella oralis ATCC 33269|TrEMBL
MRIIDIINKDTDKRRFSFEVLPPIKGNGTGSLFSTIDKLKGYDPLFINITTHHSEFVYKE
LPNGQFERQRIRRRPGTVAIASAIQTKYNIPMIPHVICSGVTTEEIEYELLDLQFLNIEN
VLLLRGDKAKEDNHFVPTHGGHAHTTDLIKQVNRFNEGFFIDGTPMKHPGIPFNYGVACY
PEKHEEAPNIEMDMEYLKKKQDLGAQYAVTQLFYDNKKYFDFVEKARTMGITIPIIPGIK
PFAKLSQLSIVPETFHCDLPQELANEVVKCKTDEDAKTLGIEWSTHQCKELYAKGVGIIH
FYTVSATDAVKEIVSKIM
>A0A5C8FDY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira aalborgi|TrEMBL
MNSVENFINKLENEKEFTFTLEVTPQAKSDLGYLVEKIKSSNIEKYIDAFIIPDSPFANL
KISPILSSLQLSQRLKTEKPFIITQTMRDKNSIALQNDLIGANYFDIRMVLALTGDPVVN
GNQKQAKGVFEGNSELLIRIIKNLNEGKSAGNFIFKEPLKKIYPFCSINSYSKNDEMLKV
RLSKKTASGVKAIFTQPIYEFETLKKFLNWIDEMPLKEMKLKEKPILFPGFFPVLSYKTA
YFIYYKLPGAYIPEEWLNKLKDASEKSAEEEKKVAFELSSNLFKDMLSVCKKMHIMSMNN
YDFVADLLKHI
>A0A659UAU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.158.01.1.1|TrEMBL
DEVEAVIEEFCGMGVKRFVALRGDPAEGVGAAYRPHPDGYANGAELVGALKGAGDFDISV
SAYPEKHPESPDFATDIDMLKRKVDNGATRAITQFF
>A0A4V3RKA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium laevaniformans|TrEMBL
MTSHEPHIAAARAGGEASPQVPFSFEIYPPRTLAQLPALHETIRVLAEAGPRFISVTFGA
GGSTTDRSLAVLTHILRETRVPPVAHVTCVGSSYAEATTVIRHFLDAGITRFLAVRGDPP
LGVGEDDIVFGDLESAAQLVQLIGRVHAERSTYREREIPGVPGAVRVIDGDRVDIAVAAF
PNGHPRSRHRYEDIDALLAKQAAGATSAITQLFFHADEYLDFVARARAAGVVIPIVPGIM
PITSPGRLRRVLELTGDARPDSLAAALESAPDAAAQREVGLAHAAALARAVVAGGAEGVH
LYAFNNHETVLGVLRTAGLIPERRS
>A0A5C8CN61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira aalborgi|TrEMBL
MNSVENFINKLENEKEFTFTLEITPQAKSDLGYLVEKIKSSNIEKYIDAFIIPDSPFANL
KISPILSSLQLSQRLKTEKPFIITQTMRDKNSIALQNDLIGANYFDIRMVLALTGDSVVN
GNQKQAKGVFEGNSELLIRIIKNLNEGKSAGNFIFKEPLKKIYPFCSINSYSKNDEMLKV
RLSKKTASGVKAIFTQPIYEVETLKKFLNWIDEMPLKEMKLKEKPILFPGFFPVLSYKTA
YFIYYKLPGAYIPEEWLNKLKDASKKSEDEEKKVAFELSSNLFKDMLSVYKKMHIMSMNN
YDFVADLLKHIC
>A0A0U3N597|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pannonibacter phragmitetus|TrEMBL
MSTSTDARRSHSSESAPVKVSFEFFPPKTDKMEATLWSTIQKLETLSPSFVSVTYGAGGS
TRERTHRTVERILKETPMLPAAHLTCVGASRADVDAVVQDYWDLGVRHIVALRGDPQEGV
GTAYVPREDGYAYASDLVAGIKAIGDFEISVSGYPERHPESTDWQVEIDNLKRKIDAGAS
RVITQYFFDNNLFEAYLERIAKAGLSIPVVPGILPILNFDQVVKFSSGCGTTIPDWLSRR
LAGLDDDAETRKLVGAAVAYEQVMDLVDRGISDFHFYTMNRAELTFALCHMLGLGQGETA
RQVA
>X6JGH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L103C131B0|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A5M3XKR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acrocarpospora pleiomorpha|TrEMBL
MDLGFPGRTCNLWGMSLGLPSRLPDRVPTVKDLLAAGERSFSFEFFPPKTDEGERQLWRA
IRELEALRPTFVSVTYGAGGGNRDHTVSIVERLAHSTTLTPVAHFTAVNHSIRELRHLVG
RFADAGVRNILAVRGDPPGDPMGTWVRHPEGVEYAEDLVRLIRQSGDFCVGVAAFPYKHP
RSATIESDTEQFVRKCRAGADYAITQMFFKADDYLRLRDRVAAKGCYTPIIPGIMPVTQM
STIARSEQLSGAPFPPEVAARFEAVAHDPESVRRLGIEHAAELCQTLLDEGAPGIHFITF
NRSSATREVFQALVPAVV
>B8HR68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanothece sp. (strain PCC 7425 / ATCC 29141)|TrEMBL
MQSIPSPIAPSRSFKAAIDSGEFLITAEVCPPKGSDPSHMLQQALCLRGRVHALNITDGS
RAVLRMSSLVSAILLRQHGLEPICQMTCRDRNRIALQSDLMGASALGISNILALTGDPIK
AGDHPDARAVFDLESVRLLQIIQKLNAGFDANDKPLSDQPTQLLAGAAIDPQLPSWSGLT
SRFERKLAAGAEFFQSQMIMDFERLEKFMDKVASGCHKPILAGIFLLKSAKNARFINRAV
PGATIPEPIIERLEKAENPLQEGITIAAEQVKLARQLCQGVHLMAVRREDLIPQILDRAG
ISPLCGDQGRLE
>A0A7S0YJX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polytomella parva|TrEMBL
MKIIDKINLKIEERRPFFSFEFFPPRTEEGVENLFERQERLVSYGPVFCDITWGAGGSTA
DVTQDIAVKMQNLVGVETMMHLTCTNMPKERLEIALKEVQKAGVKNILALRGDAPKGQDK
FEAIEGGFSCALDLVKYIKKEFGSYFGIGVAGYPEAHPDSIVDDPEQMKKNYFENIEYLK
KKVDAGADFIITQLFYDANIFIKFMNDCRAAGITCPILPGIMPIASYAGFKRMTSFCKTH
VPQHILDAVEAIKDDEEAIKNFGISYGVEMCRKVLAAGAPGVHLYTLNLERSAVGIVEKL
GIMPEQLGSRFPLPWRPASIGTDRTNEGVRPIFWANRPKSYVLRTSHWTEFPSKSWTSKL
LASAAFDSSVDQKPLSDAVNVATVTEASLASHVIGDVNKYQMTRHICSTLRQERSRASWG
IEVSNVEAVKDVFAKFYLGELRGLPWFEHDVPGAAAASIELREQLAVLCRKGILVMNCQP
SARETPATDPVVGWGPTKGYVYQKAYLEFFVAPEAFRSLLPVLQGKENVTYMASDVRGEI
FHSNAAPGDVNAVTWGVFPGHELVQPFVATLPAFLSWRDEAFALWDEDWAALYPEGSVSR
TVLKAIHDTYVLVSITENDFVNGDLLSKF
>A0A8F9MVS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polymorphobacter sp. PAMC 29334|TrEMBL
MSLSLSQMAEAGLALNAPLYADVPGDIAVSFEFFPPKTEAMERTLWESVEALTPLAPSFV
SVTYGAGGTTRERTHATVARIARETPLKAAAHLTCVDASRDEIDAVARDYWEAGVRHIVA
LRGDPPRAGEKFTAHPDGYASAAELVAGLKRVADFEISVSAYPEMHPDARSPTDDIDNLK
RKLDAGATRSITQFFFEPDTYFRFRDAAAAAGITAPIVPGILPVSNFAMLNKMASSCNTA
VPPWLARLFNGLDDKPATRQLVAATVAAELCRRLYAGGVRDLHFYTLNRAELSYAICHML
GLRPVEAAAIPQELAA
>A0A844ZHF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parapontixanthobacter aurantiacus|TrEMBL
MIRSLDEMNEARMALDTPLFSGLKGDISASFEFFPPKTEKMEAKLWDAIQELVPLGPGFV
SVTYGAGGSTRERTHATVSRIIREARIPAAAHLTCVAASKAEIREVAEQYWQEGVRHIVA
LRGDNGEPGAAFEPHPDGYANAMELVAGLKDIADFDISVAAYPETHPDATCPEADIDNLK
RKLDAGASRAITQFFFSPETFFRFRDAAAKQGIDAPIIPGILPVTNVAQARKFASQCGAK
IPDWMDGLFEGLDQRPAARQLVAATIAAELCRRLYAGGVRDFHFYTLNRADLTYAICHML
GMRPETNNVTEVAA
>A0A5V6HK01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Goldcoast|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3M7KUA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Auxenochlorella protothecoides|TrEMBL
MSKIIDTLNAYIERGQPFYSFEFFPPKTDEGVRNLQERQRRMVKLGPAFCDITWGAGGST
ADVTLEVAGAMQQEIGMNTMMHLTCTNMSIEKLHESLEKAKSMGIRNILALRGDPPKGET
SFTAVDGGFACALDLVKYIRQEYGDYFGICVSGYPETHPDLIVDDPVAMEANYRSDLAYL
KAKVEAGADFIITQLFYDVDCFLAFVRDCRVEGIAVPILPGLMPLMTYGGFKRMTAFCKT
RVPAHIAATVEALKDNDEAIKAYGISLGTLMAQRLLDAGAPGIHMYTLNLEKSAVGILQH
VGLVKVEPEAEEAEEPQRLAATA
>A0A1U9NVZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. fd1-xmd|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMAEWVAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVEKAGCDTPIIPEVMPVTGIKQLDRLPQLSTAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A0Q8E6H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root614|TrEMBL
MTTGAGRSLGEILRDGGRSFSFEFFPPKDDAGEAQLWDAIRALEPYRPTFVSVTYGAGGA
TRDKTVSITGRIARETELVPMAHLTCVGHTREELEGILDSYVAEGVSHVMALRGDPQEGP
RADWTPTEGGLNYAVDLVDLARSRGDFRVGVAAFPEGHPSAASLDQDADVLVAKAEAGAE
FAVTQMFFRAEDYFGLVERVRARGADIPILPGIMPILNLSAIRRQGELIGTSVPDDIVAR
IAAFEGDPAAVRAEGIKIAAELCDELLAGGAPGLHFYTLNRSKATLEIFEALQITV
>A0A3M7LHV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium nematophagum|TrEMBL
MKITDHIKKANGKTLFSLEVVPPQKGIGIEDLYANIDPLMEFKPPFIDVTTSREEYVYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKDETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVHQINDLGRGKYLHNQDQICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELIAEVEKAKNNDIVKQIGVEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKNVARELF
>A0A3S0ACV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC00469|TrEMBL
MALGTASIRSDHAPTVRDMLATGKRTYSFEFYAPRTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHITAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPQGLTYAAELVELIKNSGDFCVGVAAFPAMHPRSTDWDTDIRHFVA
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCDTPIIPEVMPITSMKTLMRVPQLTNAVF
PPAVKERMVAAKDDPAAVRSMGIDFATEFCARLLAEDVPGLHFITLNNSTATLEIYDNLG
LHHPPRA
>A0A1F9ZKH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFOXYB2_FULL_62_6|TrEMBL
MRITERFKKPGKVFSFEFYPPKTEVDAQKLFETVRDLEALGPDFVSITNSTAGTSPYSTV
ALSGVIKEKLGLEVMAHLTCIGHTRAQIAEIAARLKTMKIENVLALRGDLHNIDGLDPKR
DYKYASELAGELAATGSFDIGVAGYPEKHPEAPDLDTDIRNLKAKVDAGAGFVITQLFFL
NRFYFEFVDKARRAGVTVPVLPGLMPLTSYKQLQNFSKMFTVELPREIRENIEKYSGDKD
SLMKFSVDYATAQAADLLKNGAPGIHFYTLNRSRATKEILKNLRGIEL
>A0A2P6AS02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amnimonas aquatica|TrEMBL
MSHFSIEFFPAKTEVGAGKLREVARRLGELGPEFFSVTYGAGGSTRDRTLGTVKDVLALG
YDVAPHLSCIGDSREEIGELLDLYRELGISRIVALRGDLPSGMGRGLGELPYAADLVRYI
RERHGDHFRIEVAAYPECHPQSGDLGSDIRHFVTKAQAGADSAITQYFFNADSYFHFVER
VRAAGCDIPVIPGIMPITNFANLVRFSDACGAEVPRWVRKQVTAYGDDAASIQQFGEEVV
TRLCRQLLDGGAPGLHFYSMNQTEPTLALWRNLGL
>A0A4V6X7H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. CCUG 61487|TrEMBL
MVFGPCGGVRGNERCEVAEHRCVFLDGPLPAWPDPPAAPAAVSGLLTAAARGPVVLSDLT
TAPFDTDSVRRVVEVLAPVSDALLAGEYANRPDFPPTMLAARVLDAGGRLWTTLTCRDRN
RVVLEQELAGLAALGVDGVLTVTGDARGPGVRAGATQVFDLDGPRLAALASDVGLPVAVA
ESPEAPPAGARPARVAQKQRAGAQLCVLNHVSTPARVAEFVTAARAAGATLPFVAGVAVY
TDEPSARVLQRFPGLHLDDARVEQVLAAPDPRAAGIEAAVEEARALLAVDGVVGVNLSGM
GSARGEDDGARVKAAVAAAVGGAR
>A0A4V1P4T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium erdmanii|TrEMBL
MSARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A3D1P4G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp|TrEMBL
MTDRAQIDAEGLNPGDPLPMLPGHVSHGRFERVLRAGHFAVSTEIAPPDSADPDEVLRRA
ALFDGHVDAINATDGSGANCHMSSLAVCALLTREGYSPIIQISCRDRNRIAIQGDLLGAS
ALGVCSVLCLSGDDVSVGDHPEAKPVFDFDSVSLLQTVRTLRDESRFLSGRQLDLPPRLF
LGASINPFAPPHTARVDQFAKKVAAGAQFVQSQYCFDVDMAREFMARSRDLGLTERCFVL
MGVGVLASAKTARWLRSAIPGVHIPDAVIRRLEQTEKPKAEGRRIAIELMQQLAEIDGIS
GVHLMAFKQEEWVGEIVTQSGVLQGRKPWAPAHLAHLKQPASA
>A0A0Q8EAJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root614|TrEMBL
MSRRDRTDVLADLLARVRYEVLPTAKVVDDASASLPVGATVTVTASPAKGLGATLETAEL
LAGAGFDVVPHLAARMIAGPGELAEIAARLREAGISKVFVPSGDATAQAGAYASALQVLE
DLAVAGNPFAEVGVTGYPESHPSIEDDLTIQAMWDKRRHATQIVSNLTFDPAVLAAWVRR
VRARGVDLPILVGLPGPVERVKLLRMASKIGVGESARFLAKNGGLFARMAAPGGYDPLRF
LDRAAATLGRADMNVAGLHLFTFNQVAETERWRIAELARLQDAPPRRRARARVGAPKQSA
S
>A0A1E4FZQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium SCN 62-11|TrEMBL
MESTTRAKSFRDRLQQEIIVFDGGLGTSLYDKGIFINTCFDELNLMNADLVRDVHREYVA
AGADVIETNTFGANRYKLAPYGLEKRVHEVNQAGAKIAVAAAADKALVAGSVGPLGVQIE
PLGKISLDEARAAYKEQIQGLIDGGVDLLILETFHMLPELEQAVKAVREVAGDFPLIVQV
TIGDDGKLLSGAPLSQFVAMITEYKPDAIGLNCSVGPKAMMDALEELKHLTSLPISLQPN
AGLPQTVGGRNIYMTSPEYMAEYSKRFIQAGASIVGGCCGTDTTHIKAIRRAVSALQPAK
RMEQAASLQIQAPVEVKVATMAEKSRLANKLMRKQFVTLVELVSPRGVSPIKELEKARKL
HHFGIDAINIPDGPRASARMSALAMTALIQREVGIEPVLHVACRDRNVIGLQSDLLGAWA
LGIRNLIAITGDPPKLGNYPDATAVFDVDAIGLVNLINRLNHGLDLAGNPIGEPTAFNIG
VGCNPGALNLDEEIRRLDWKVEAGADYIVTQPVFDVRILEKFVARIQHIKLPILCGIWPL
ISYRNAEFMNNEVPGCSVPDDILERMRKTTTKEEGFAEGVKIASETFRLLKNDFAGVQLS
APMGRIEGIFQILGD
>A0A3A4NM50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MMMNTTFLDAVRERVLLADGAMGTELYSRGFFVNRCYDELNLSNPESVKEILEQYAGSGA
EILTTNTFGSNRIHLASYGLAERTEEINRKGVELARQAAGQNLFVAGSIGPIPTFSSLHK
EKEAILDSFREQATYLLESGVDLLLLETFPSLEQLELAFKGSRQACEVSIKMDVSSFPII
PSISLSVFSGENPISHAHVVQSVRSWGARFLGLNCGGGPPEMLEELPLIIGEAGDELKVS
VMPNAGLPKIVEGRTLYMASPEYMAEYTRRFVQKGAAIVGGCCGTTPRMIKEMCSFLRSV
QPGRAISIRAVDTKDEIEVMQPIPIKERSGFGRIIGEKFAISVELDPPKGINAEKSVEGA
KFLYEHGIDAVNIADGPRATGRMSPTALALLVKQQAPIETIIHICARDRNLLALQMDMIS
ANALDLHNLMLITGDPPKMGLYPDSTAVFDLDAIGLVRCANLLNQGLDFAHRPLRDQTSF
VIGVGCNPAAADLDLEVRRYEQKVNAGAEYVFSQPIYDPELLDTFLQCIAPIRPIPFFVG
ILPLASYKNAEFLHNEVPGMQVPNEIRERMRLAPTKEAQREEGINIAAEALREAARNPRV
KGAYIFPPFGRYASILDVLEKAGIR
>A0A7U9HJD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia acidovorans CCUG 274B|TrEMBL
MSFPISFEFFPTKTPEGATKHVQVRKNLYARKPQFCSVTYGAGGSTQTGTFAMVRDIQNE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPQSDLDAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A6G6TDB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus sp. ZN5|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTEEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASREELQHIAQDYWQSGIRHIVALRGD
LPDNTQKPDMYATDLVHLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMFD
GLDNDPETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPELVQA
>A0A1W9TEW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_123|TrEMBL
MLRVFRNELQEPDRFTVTLELVPGRETRGRSVDKVMGIARDAFADGRVSAVSITDNPGGN
PSLSPDVLGYEIFKTGMDVIVHFTCRDANRVGMESRALQLAKMGMKNILALTGDYTGKGF
GGQGAPVFDLDSVHLQILLSMLTKRIRASGDPDGFFTGCAVSPFKSTEGECYAQYAKFCR
KTAAGAKFAITQLGYDARKFEELMLIQERMDRSLPTLGSVYLLTPRAASVMNQGKVPGVV
VPDKLLDAVRREWQNKKAGLDAAVERAARLAAVLKGLGYKGVHIGGIHGSFEAVGRILDR
LSLIEKDWKKFLPDFEFPQPGVFYAFPRRKKVEKAAKPVPRFGEYKTHLGLMEKMHFHLL
RKVHNIFFTFNSPLAPLNHNLCRLLTKWRQGALFMHLTEDPAKKLLLRCERCGDCGIQHV
GFLCPQSGCPKHMRNGACGGSRDGYCEVHPERFCVWYRAYGRWASVGTPEAMREGCVPPR
MWELDRTSAWLNFHLEKDHQSASNELARFCRERSCSL
>A0A829SBF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis str. 3774 T13|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A0W8DNI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora nicotianae|TrEMBL
MGKIIESIRSAYAARADDASARPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGAERWSPVEGGLSNAVDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIQWISDCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPEKVLTALDAIKNDDAAVRRYGTQLAVETCRRLLAAGVNSLHFYTMNLATT
VTQVLEGLQLLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRTELWGTPQTEEDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAAIRENLQWLNSNGFLTINSQPRVNGAPSSDPSVGWGGDDGVVFQKAYVEFFVA
PEKIAHLVKVMRRDYPQLSFHALNRRGDEHRNTPLHSVTAVTWGVFPGIEIVQPTVVDSD
SFAAWKDEAFELWQTQWASAYPEGSCSREVIQHIYDSYFLVNIVDNDYANDDSDIFSIFT
RIITEAMDKEELRTRVLELEARREKMFDTLASFQSLQKDLNGELRAAHSELAGVRGENLQ
LKEKVRQLEAQLALASL
>A0A0C1IAV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. C5pp|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSTERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSRQATPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGTHSLLFSRRNSLSKAF
GWAVRQPMWATRLGAQVLHKVEHAVKHPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQMALLTERLIPCIELETRHRSSWPQWFQAQTP
RQLSPQPAPRTQPES
>H2YN67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciona savignyi|TrEMBL
KQESLTEKILSRVKSKDPFFSLEFFPPRTEQGAANLIGRFDRMRQGGPLFVDITWHPAGD
PGGDKITSSTKIAGTVLNYCSLDTMLHMTCVKQTEETIKKNLEKTKNLGIRNILALRGDA
DENWGITEGGFNYGVDLVRFIKKEYGDYFSICVAGYPNGHPDSTSYQEDLLHLKEKIDAG
GEFVITQLFFTADEFLTFVKDCREIGITCPIIPGIFPIQTNRSLVQLTKLSKLTIPEEIQ
KVIEPIKDNDAAIRKYGIDLATDMCRSLLNSGEVHGLHMYTLNLEAATIQILKNLGLWCQ
DVAKTLPWKTSGNPERRENETVRPIFWTDRPKSYIHRTQKWDEFPNGRWGDSASPAFGEL
RDYHLFFLRCRTSKDRLRAQWGKELTSETDVWKVFQNFITGAVNENGVKVLETPWNDDGL
SQETNLMSKKLSQYNARGVLTINSQPNVNAVPSTHPIFGWGDKGGYISQKAYLEFFINKR
YAEALKVVLPKYHPRVNYHMINRCGAIDHTNADRSRPNAVWGIFAGKEIIQPTVVDPISF
IVWKDEAFGLWTERWASLYAADSNSRKVIDDIADNYYLVNLVDNDYPSESVLWNVLDEMI
AESQDSVVK
>A0A3Q2HUW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Equus caballus|TrEMBL
MDHPKPKVLLARHCCPSLGMWASEAGSVRFSVPPSISRNRAMVNEPRGNGGPIPRSDGSS
SGSESSRDSSRCSTPGLDPERHERLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DQMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETVLHMTCCRQSREEITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKG
HPDSGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDGAIRNYGIDQAVSLCQQLLASGLVPGLHF
YTLNREVATTEVLKRLGMWVEDPRRPLPWALSAHPKRREEDVRPIFWATRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGVLTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNDFPLDNCLWQVVEDTFELLNRPAPNEREMEAP
>A0A0E0VLA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus 71193|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTNRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A2E9CPN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp|TrEMBL
MTLNDPAAPLYADLAGDCHVSFEFFPPKTEKMEAQLWSAIETLTPLQPKFVSVTYGAGGS
TRERTHNTVARIARETPLAAAAHLTCVGASKAEISEIADAYWEAGXRHIVALRGDPPEVG
GTFEPHPEGYKGAAELVEGLMQRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFTPDAYFRFLDKILAAGITADIVPGIMPVSNFAATQRMAAMCNTQVPSWMGRLF
EGLDDHPASRQLVSATIAAELCRSLYGGGVRDFHFYTLNRAELSFAICHLLGLRATASNG
GTA
>A0A239AT04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. ov086|TrEMBL
MKVTEHIENAKGKTLFSFELIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKKGGNSFAIDLVKQINNLNCGKYLHEVMDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFTFVEKAREMGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQIF
>A0A1M7MXY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas cupida|TrEMBL
MSAQEHPLGISFEFFPPNTDAGREKLMHTRDMLAERNPRFFSVTYGAGGSTQNRTIDTVN
AVRQCGISTAPHLSCVGSEKSQLRELLLSYREQGIDNLVALRGDLPSGMGGVGELRYANE
LVEFIREETGDHFQIAVAAYPESHPQAPSFEADLQNFARKMNAGANLAITQYFFNADSYF
HFVERARQLGVEAPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSESIAAF
GEEVISRLCRRLLDGGAPGLHFYTLNQAAPTLKVVDNICSPH
>A0A1E3NQ54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pichia membranifaciens NRRL Y-2026|TrEMBL
MKITDKLAQAHKDDKAAASFSFEFFTPKTSQGVQNLYDRMDRMYHLNPLFIDITWNAGGR
LSTLTSEMVHTTSTVLGLETCMHLTCTNMPLQLIDDALQKAYLSGCQNILALRGDPPLDG
SESTGDFKYAKDLIRHIRAKFGNHFCIGVAGYPEGHPEEPDHAKTLSYLKQKQDEGADFV
VTQLFYDVDNFIDWCARCRGAGITLPIIPGIMPISNYNAFLRRAKWNNVAVPQSFIDRLA
PIKEDDSRVREEGCLLMAELCQTLLDSKHVNHLHFYTMNLEKSTTMLLDSLHLVSNQTKQ
DYECENSKPWRKSLNPSRELENVRPIFWKNRKFSYIQRTNNWDEFPNGRWGDSRSPAFGS
LDMFEHNIIRHSPTKILQLWDRPTNSHELGELIVRYLNNEIHCLPWSDTQATEEIDTIKP
DLVQLNMNGVITINSQPKINGVKSTDHVFGWGPTNGYVYQKQYLEFLLPKTKLAKLVSQI
TAVNEENGYDTLNYFVTDAESNKLSETNVTDLSDVNAVTWGCFPGREIAQPTIVEKVSFL
AWKDELYLILKKWSNVLLASSSDEEGEPDEANRLRDLKSSNFIQSLIKDYVLVNIVDNDY
IQPSDTIFHILKNL
>A0A3M3NY42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. savastanoi|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>A0A1M7DRJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas cupida|TrEMBL
MNDFHHDVLAAAALVPATRFELLPITGMQKAAQQLPVGALVTVTCSPRHGLERTLEAAEW
LVEAGLRVVPHVAARLVRDRAHLEDLLRRLVARGIDDMFVVGGDAQRPLGIYPHGLALLE
DLKDSTLRPTRVGVPAYPEGHHHIETPRLQQDLEAKAALADYVVTQLCFEAQPLLEWREW
QARLGLRLPVHAGIPGVIKRKRLLSIALRLGIGPSVKSLQRQSGKMRRWLGPSTYRPDAL
VEDLTSALGEPDNGFVGLHIYTFNQVAPTRAWLEELETPLLAPSPC
>A0A099W0Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeriaceae bacterium FSL A5-0209|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARIAAPSL
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIVANVSMHEPGLL
QSGQTLASALQELADLGADVVGANCRLGPYHMSKALESVPLLENAYLAAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRRGLKSLKPVTSKVVHPIL
ELAELDAAEDAGVRLTDKVKEQYTVLVELDPPRTFDTAKFFEGAQKLDAAGVDAITISDN
SLATPRISNMALAAILKQEYDIRPLIHLTTRDHNLIGMHSHIMGFHKLGIQDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALVEAGITVPVFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREADKSGTGREEGMAIAKEILDAICEHFNGVYIITPFLRYDLSIE
LTKYVQSKETIAEVSSQN
>A0A7C5T7N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrobaculum sp|TrEMBL
MEIIAEVAPVRDRAKLLKKLEALKPLVDKIDIPEAPGGQPTAHSLAVGALAKQIGFEPIV
HIRLLDVNKTGLKSLLGGVYVLDIKHVVVLQGDPPAEGRPVGEVSTEEAVEEAKKMGLRA
GALLSLRRDYRRRVETLGADFYLALHLADVKQLKGLPPVVYPYVMVRTSNNSALIERLRQ
TAVELHEALALVEALEGVAPGAVISVPGDFETLLRLLRQIKTRRS
>A0A832GTT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MKVIEHLNRAKNPLISFEIIPPLRGGDISQLFSVIDEIVKFNPPFIDVTSHAAEVIYEET
PKGIKKKTLRKRPGTIGISVAIKNRYNIDTVPHLLCQGFTREETEDALIELNYLGIENVL
AIRGDDKGYKKPIPVGKTSNETTLELVKQIVDMNSGNYLEADLMDAVPTDFCIGVGGYPE
KHFEAPNLKIDIQNLKQKIEAGAHYVVTQMFYKNDSFKNYFKLCREAGIQVPIIPGLKIL
TSKKHLTTLPRDFFIEIPEELAEEILKADQKHTADIGIEWALKQVEDLLNFGVPAIHFYI
LQNAEPIKKLFSKLNL
>A0A7S4AJZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudo-nitzschia australis|TrEMBL
MSSADANPKIIDLIKEKKDGSKPFVSIEFFPPRTETGVKNLYARMERMKASINPLFSDVT
WGAGGSTAELTHDIAKQLKTTGHVANMHMTCTNMENDGDPKKAVHDALETAKNNGIMNIV
ALRGDPAHGQEEWTAADGGFTCALDLVEYIRAEFGSDLGISVAGYPEGHPNAISLIEDPS
TMTESEKARSSTDDEGKVYTCRDDDYKKEMDYLKKKIDAGGDFIITQMFFDTKVFGSFVK
DCREWGINCPVVPGLMCINAYAGFVKMTKFCHTRVPAELRAKMDGLKDDPDGVKAFGIEF
GIQMCRDLIEIGVDVLHFYTLNLEKTTYGILNGLGYDVSGAADDSDEKTMVAKGSAWARV
GDKVKTSDGGIEGTVTAIESDGTATIEFEGETPTVTLKKEEYSKVF
>A0A7C6AC27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MTLREKISAGKFVVCGEMEPPKSCDAETIKKKSAYFKGYVDAVNITDNQTAVVRLSSLAS
AKILLDEGLEPIMQITCRDRNRLAIQSDLLGAAALGIRNVLCLTGDHQRFGDQPEAKGVF
DLDSIQLIATVTNMNNGYLLSGQELKKATDFFIGGAANPSGTTFEMQLIRLYKKVKAGVH
FIQTQPVFDLERFNKWMEKVKEMRLHEQCAIIAGVMPVKSVNALLYMKNEVPGMRISNEY
IERMSKATDPKEEGIKIAIEIIQTLKTINGIKGIHLMPVMWESITPTIIEQSGLAKR
>A0A7V1TWV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MHIADVLKQPGPHFSFEFFPPKTEEASKALFESIKELSPLKPSYVSVTYGAGGSTRQLTH
DLVVRLKKETHLTVVSHLTCVGSSKDEIYSILSKYAESGIENIMALRGDPPKGQTNFQPH
PNGFKNAAELVTFIKKHFPQLGIGVAGFPEGHPDTPNRLKEIEYLKAKVDAGADYICTQL
FFENADFYDFCERCELAGIHVPIIAGIMPVTSRKGLARMAELALGARFPAKLLRAISRAE
NDEYVEKVGVHWATQQVMDLLDHKVAGVHFYTLNKSKATLKIYESLGVQSSDGLRKAPTP
LTS
>A0A5C4RNA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus luminescens subsp. sonorensis|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSIGRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLDAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGD
LPENGEKPKMYGADLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQLKRFAAMTNVRIPSWMTRMFD
GLDDDPESANLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A521IHQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MKISEILQTNKLTVSFEIFPPKQDSAYDAVIGCADELVRFDPDFMSVTYGAGGGTSANTV
KIAAHIKDRGITSIAHLTCLSSTTSEVHRIIGELKDRNIENILALRGDRPKDPDFVPPGD
YRYASDLIRDIRESGNFCVGGACYPEGHPESGHKDRDLDNLKLKVDAGCSFLTTQMFFDN
NMLYSFLYRAQSKGINVPVLAGIMPITNGAQLKRTIELSNAYLPPKFLALVDRFGDSPEA
MKQAGIAYATEQIIDLITNGVRGIHIYAMNKPDVVQKIVSNISDIIKAAK
>A0A136A2B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraglaciecola hydrolytica|TrEMBL
MVSYAQGIDALNQSLSEVKGINVSFEFFPPKTDAMEQTLWKSVERLAPLKPAYMSVTYGA
NSGERDRTHDVVKRIQAETGIAAVPHLTCVDATKEELIQIAKDYWASGIRKIVALRGDLP
PGIEKPQSYASDLVALLKSVADFDIAVAAYPEKHPEAPNSQFDLLNLKRKADAGATEAIS
QFFFDAEVFLRFRDRAAAAGIDLDIIPGILPVTNYQTLQRFAGFTNVHVPQWLHKMYDGL
EQDDQTTRNLMGASIAMDMVKVLAKEGIRNFHFYTLNRSELSYAICHMLGVRADK
>A0A3C0U316|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MIDNALFASRPAFSFEVFPPKKDDGIEKVYDTLDELSDLHPDFISVTYGAGGSENCGKTL
DIAKRIKNVCHVESVIHLPCLHLTKQEAEKMLLEFSDNGIDNLLILRGDKIEGREPSGDF
FHASDLIKFIQEKMPGRFHLLGACYPENHPDSKNVFDEIANLKIKVEAGARHLLSQLFFD
NDQFFRFTENCRFAGISVPIEAGIMPVTNKLQIERMTSRCGVELPQKYKIMMEKYGSNDN
AILEAGITYASNQIVELLSSNVDGIHLYTMNKPYIARRLAEVVEPLILRKKQ
>A0A2D7AQX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pelagibacter sp|TrEMBL
MNLQNSDSPNSASQEARCIIELLNNFSLETTPSGAKXIENFSNFVRPNTTVFITFLPGSD
YKETVLTAKKLRVEGLNPAPHFAARSIESKQMLEDYVKRVTGEAAVTKILTVAGAGKEQL
GPFPDSTSLLETGIFDKYGITEIGVAGHPEGSPDISDEEIQKALLKKNKYSDMTNAKLFI
VTQFCFQSEVILEWARKINSEGNKLPIIIGIPGIAKLSTLMKYSISCGIGNSIDFLKKQG
SKMVNLIKTQTPDRLIRELARGKXDNGALRIEGLHIYPLGGLQKSSXWXFKTLDGKFKMT
KDGFEV
>A0A3C1SHN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
PVLAGIMPITNANQVSRMVDLSNAYIPRKLLAICDRFRNSPEAMMQAGIAYATDQIIDLI
SNGVRGIHIYTMNKPEIAKAIIQNVDSIIKATNYSCSSQGMPNM
>A0A2U8QHM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium symbiodeficiens|TrEMBL
MTDLTIPARADGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDGIVDRYHEVGVRHIVALRGDPAG
GIGTPYSSHPDGYQNSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLQAKVDA
GAARAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKNGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A520HCY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
MSISITQLGEARRALEEPLFADLAGDIGISFEFFPPKSEKMDAQLWDAVRTLEPLAPDFV
SVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIVA
LRGDMPTLGQPYQPHPGGYENAAALVAGLTRLHPFEISVAAYPECHPESGGHDADLDNLK
RKLDAGATRAITQFFFSPEAYFRFRDRVAEPEIGLGREEE
>F3YV77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocurvibacter africanus subsp. africanus str. Walvis Bay|TrEMBL
MRISDLMRKRRPFVSLEFFPPKDQNAWPLFFEEAERLKAAKPLYASVTYGAGGSGQANTL
EIAKRLKNEVGIEPLVHLTCVGASKEKISEFLTELRKAGIENILALRGDPPKGSCDFVPD
NEEFQHASDLITFVRRHFPEFCIGAAGYPSPHPQSPSIEEELKWTKFKIDRGADFILTQL
FFDHRLYEDFVTRLRNMGVSVPIIPGVLPIMSLQSIRHILALCGANIPGNLYLDLEKAHE
QGGSEAVRRIGIQFATSLSKKLFELGAPGVHLYTLNKADACLEIVDGLKL
>A0A6I3LY06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. LC2016-01|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAIDLVRQINDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A6P3BUX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DTRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNTAAATRTICERLVM
>A0A7H8KHZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucosispora sp. NA02020|TrEMBL
MALGLPSILPNSQPAIGELVRDCQPTFSFEFGPPRTEQGERQLWQAIRELEPLRPSFVSI
TYGAGGTTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPNGEWVPHPDGVDYAEDLVRLVRRSGDFSVGVAAFPYRHPRSVDVQTDTEYFVR
KCRAGAEFAITQMFFDADEYLRLRDRVAAAGCDTPILAGVMPVTKIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQTSEMCRRLLDEGVPGIHFITFNRSTATREIWQNLR
VGAAT
>A0A841PE62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sangaii|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGADLVAGLKMIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDQDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEPA
GTAAA
>A0A2E4V1X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVVDYIKNSNKTIFSFEIIPPLKGKGIEDICKGIDPLMEFNPPFINVTYHREEYEYKKM
GNGLLKKVSIXKRPGTVGICAALMNRYKVDAIPHIICGGFTKEDTESALIXLKFLGVDNI
LALRGDPMKXESAFIPTDGGNXFAIDLIEQINDMNNGQYLYEETKNSPSNFCIGGAGYPE
KHFEAMNLKSDLKHLKEKVDAGMEFIVTQLFYDNKKFFEFEKKCREIGITVPXIPGLKPI
TNLRHLTFIPKFFNTNFPEDFSNELEKCKTNDEVKKVGVEWSTMQSQELVKAGVPVLHFY
TMGKGESVKNIASKIF
>A0A1V3IL51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter rarus|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMETMLWDSIHRLKVLEPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLDAAPHLTGIDATAEELKQIAKDYWDSGIRRIVALRGDEP
KGYEKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIESYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPTWLAKAYEGL
DDDPTTRNLVAASVAMDMVKILSSEGVSDFHFYTLNRSELTYAICHMLGIRPKA
>A0A2N0LZU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium MP-SAtl-SRR3965592-G1|TrEMBL
MKIKDILTKTRPVSFEFFPPRNAEGIPAVLETMDELKPYCPDFVSVTYGAGGSTRAFTEE
ITLQIKRETGVEVMAHLTCVGQNKEEIDEVLQRLESEGVENIIALRGDPPRGSTEFVPVE
GGFQHATDLLKHVQSNFRFGVAAACYPEGHTESVDLDTDLDYIKMKVDNGADFLVTQLFY
DNRHYFDFLERAHAGGIDVPIIPGVLPVLNSAQVRRFTALSGSEIPPDLDKLLDKYADSD
NSARDMGVEYATAQVRELWDAGVPGVHFYVLNRSYSVSRILDNLTISGHQRQD
>A0A1F0RGR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC056D07|TrEMBL
MSIQSPSLSFEVFPPNPAVGNENIMVALKEMQDLAPHFISVTASNNKFNIEETTVRLADF
ICNGLHIPTIAHLPAVYLTKEMVTETLTVLDKIGVHKVLALRGDILRDVEPQKDFVYATD
LIEYIKKEAPHFEIIGACYLEGHPDSPDRVSNIKNLKKKVDAGCSSLVTQLFFDNERFYD
FQERCTLAGIEVPIHAGIIPILNRNQVLRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSSTAHQIYQATHTFFNNKVSS
>A0A423KPT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas frederiksbergensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLKQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A2R5EFE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospira sp. I13|TrEMBL
MSDKTFSIEFFPPQTAEGVEKLRLVRDKLAALKPAFFSVTYGAGGSTRERTFSTVREIAA
AGLEAAPHLSCIGSSKESIRAILDEFKAEGIHRLVALRGDLPSGMADPGEFRYANELVEF
IRAETGDHFHIEVAAYPEWHPQARSAEDDLQAFVRKVKAGANSAITQYFYNADAYFHFVD
AVRAAGVTIPVVPGIMPIASFSKLARFSDACGAEIPRWMRKKFEGFGDDADAIKAFGLDV
VTELCERLLAGGAPGLHFYSMNQAGLTTEIWQRLGLGKR
>X5Y7T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNJC405B00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A2E4YS55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVTEHISNSKDTIFSFEILPPLKGKGIEDLYAGIDPLMEFNPPFINVTYHREEYQYKEM
GNGLLKKVSVRKRPGTVGICAAIMNKYKIDAIPHLICGGFSKEETESALIDLKFLGVDNV
LALRGDPIKSEQIFTPAQGGNAYALDLIKQMDEMNQGQYLHEETKNNPSNFCIGTAGYPE
KHFEAMNMSTDLKYLKMKVDAGADFIVTQMFFDNSKYFSFVKKCREIGINIPIIPGIKPI
TTLKHISFLPKFFHVDFPDALSNELSKCKTNDQVKQVGKEWGINQAKELKDNNVPVIHFY
TMGKGESVKNIAKAVF
>A0A519JM38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haliea sp|TrEMBL
MNLPISLEFFPAKTTEGAEKLRAARRALYALEPEFCSVTFGAGGSTQDGTLSAITEIMGE
GRSAAPHLSCIGQDKASIRERLAAYTQAGVTRIVALRGDLPSGYGASGEFRYASDLVAFV
RAETGDRFHIEVAAYPEIHPQAKSPDADVEAFIAKVRAGADSGITQYFFNADAYFRYVDE
LGRRGITVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDNASIRAFGLDVV
TDLCEQLRAAGAPGLHFYTMNQSVATLEICQRLAG
>A0A817MUB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood2|TrEMBL
MTLTHTEKNAASNHHDAHENGIGAENMSNSSHHFVDLKRSESEHACLAARGNSLQPVKYV
SLTEKIEKKIANNDRWYSLEFFPPRTTNGAVNLIGCLERMATGDPLFCDITWHTAGDPAG
TKETSTMMIANTMLNYCNIDTMLHITCYGAKKATMIEYLSKAKNFGIRNLLALGGDPPVG
ETWDPEKNDFRYASDLVKFIREHFGDYFVICVAGYPKGHPDSKNYEEDLGYLKEKVDCGA
DFIITQLFFQAETFLKFQSDCRAVGITCPILPGIFPIQAYASFKNIVRLTKLDVPDAIQT
HMESIKDNDQAIRDFGVQTCVDLCKALLDSGKVHGLHFYTLNREYATTEILKQLGFGFED
PPLRALPWKKTSRNHVRSKEDVRPIFWSTRPKSYIHRTSNWNEFPNGRWGISSAPSFGVL
TDYHLFYMKIDAAHNELLDEWGHELTSEQDVWKMFACYIGGEKNSSDKIVRHFPWKDEDM
SLETNLIHNELVEYNRKGILTINSQPAVNGKPSTDPIFGWGEKNGYIYQKAYLEFFTSAN
NIPALRAVLKDFPGVNYHFVNKSGEVNETNTDDEQPIALTWGVFPGKEIIQPTVVDPVSF
MIWKVTNLNAFNFNYSYYFFNIKDEAFNLWMERWGKLYEAGSRSYSIIEQISNTYFLVNL
VDNDYPQGSCLWAVLDAMFEYQQKTNQDTNS
>U2QXF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium ramulus ATCC 29099|TrEMBL
MIREYLKEHILITDGAMGTYYDRKKSENGRIAEEANLLEPELITRIHEEYLEQGARLIRT
NTFAANHAMALGRGVRDRREQDAYVKHVIRAAWKLAQKAAENRPEEIFVAADIGPAAENL
FSEYETDPAAEYRFLADCFLECGAQIFNFETFSDIKYVAKTARYIKEKCPEAFVMVSFAA
NRNGYTTQGISISRLFAEAAQTPEIDSYGCNCLLGAAHMYKLIKAQNLAGDKFIQVLPNS
GYQQIVRGQAGHADGVHYFADKMEQMVELGVNIIGGCCGTTPKHIRMLCEKLAGKAPYEK
LPVVEKGGEDAVSQTRNNPFMAKLQRGEKVIAVELDPPFNQDAQKLMEGAFQLKQSGVDI
ITIADSPLARARADSVLLAAKVSAMVDIPVMPHIACRDRNRISMHSTLLGAHINGIRNLM
IVTGDPVPSGERDNTKSVFDFNSIRFMEYVKELNQEIFLQDAFSYGGALNQNQANEDQVM
KRMQKKIDAGLSWFMTQPIYSDEEVEKLGRMKQELNTKILCGIMPLVSYRNAMFIKNEMP
GIQVPDEIVAQYRPDMSRAEAEDVAVRISLSIMEKLEEVADGFYFMTPFNRVSLITRIIH
ARKPQ
>A0A7W8VYI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. Cpub6|TrEMBL
MTFLTMNPIELSFEFFPPKTQEGIDKLRATRAELVSLKPKFVSVTFGAGGSTQQGTLDTV
VDMAKEGLEAAPHLSCIGSSKDSLRAILNEYRAYGIRHIVALRGDLPSGMGAVGELRYAS
ELVSFIRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAY
FRFVDDARQLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRA
FGLDVVTALCQRLLDAKVPGLHFYTLNAAASTKAICERLAV
>X6NKF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reticulomyxa filosa|TrEMBL
MNSSTKQTDLVLWLLLTLKRSLLPFFFFDKKTLLAFVVLFEETKREKEDFQYDTSKTSGE
HVAKIADVIAKHIKAKKKFFSLEYFPPKTDATSAQLEVTLCEMSSWGPQWMDITWGAGGT
TSELTSAIAGYIQNECGTPCLMHLTCTNMEKHKIDDALSLARKINLRNILALRGDAPKGV
SEWTAVDSGFTCALDLIKYIKQEYKDYFSIAISGYPEGHPNVRHKITDPKWNPKTNNPKY
WAPRPIENGKAWEGVSMEDWQKELKYLKEKVDHGGQVIITQLFYDVDIFFEFVKQARAIG
IRVPILPGIMPIRGYALFARMADFCKTVIPDKLAQALEPVKHSDAQVLVVGNIVFSIAIF
YKYICMAWIKQMCRAIYDSELDIPGVHVYTMNTHETPALILDDLRLIESNHALKVREKEA
GFKQMSTF
>A0A2E3UKZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actibacterium sp|TrEMBL
MPAPRISFEFFPPQSLEASFRLWDTVQTLAPMKPEFVSVTYGAGGTTRKLTHDAVTTIHK
NYGLNVAAHLTCVDASRDETMEIVNAYAEAGVTEIVALRGDPPKGQSGFTPHPDGFADSA
ELVAALAETGKFNIRVGAYPDPHPEAKTGGDDVRWLKKKIDAGASSAITQFFFEAETFFR
FRDACEKQGIDAPIIPGILPIDNWSGVRKFAARCGAHIPAWLDDAFEAAARDGREELLSA
AIATELCSDLIDGGVEDLHFYTLNKPHLTRDICHSLGVQPGMILENVA
>Q5FNV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter oxydans (strain 621H)|TrEMBL
MNTNLKRLLSGKLADHPSLCHSDMPVPVLSFEVVPPRTDAMEQRLWQCMRRLAPLSPRFV
SVTYGACGTMQAQTQATVLRLKQETTLVPAAHLTCIGATREEIDDIARTYWQAGVRHILA
LRGDAPAGTDYTPHPGGYAYAGDLVAGLRRIADFEISVAAYPETHPTAPNPQADIDNLKR
KFDAGASRAITQYFFEASTCLRFLDRCLAAGITAPIVPGIMPVSNYDHIARFSAFCGVTV
PVWLTHLFEGTAKNPELCRIAACIVAAEQVRTLQSHGINEFHFSTLNRPDLTCAIAHLLG
VRPASETDS
>A0A0Q7T6W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. Root1423|TrEMBL
MSIAPRSLAEARALLLSPLGPIARAGQDRSRPRVSFEFFPPKSDEAEANLWKAVTRLAPL
EPEFVSVTYGAGGSTRERTHRTVERILAETSLTPAAHLTCVEASREDVDAVIEGYRDAGV
RHIVALRGDPPGGNGIGGVYVPRTDGYANATELTAAITAKGGFDVIVGCYPEGHPESPST
AHDIDVLKAKVDAGATRAISQFFFDIDAFLRFRDRVRAAGITIPMSPGIMPVTNFNGLKR
MSAACGAAVPDWLAAHFDGLDDDPETRKLIAASVAAETCARLQEEGFADFHFYTLNRADL
VYAICRVLGVRETKAATV
>A0A061SLF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter mediterraneus|TrEMBL
MPTPAVSFEVFPPRNVDAAFKLWDTAQALAPLAPRFFSVTYGAGGTTRDLTHDAAHVLAR
TSGLPVAGHLTCVGASRADTLAVAKGYAEIGVTDIVALRGDPEGGADTFTPHPDGFQDSC
ELITALAETGTFNIRVGAYPDVHPEAADAQANVNWLKRKFEAGADEAITQFFFDADSFLR
FRDACAKAGIDKPVTPGILPIVNWKSARSFAQRCGTPIPDWLDQAFDAAIRDDRHDLLAT
ALCTEMCSKLVDEGVDALHFYTLNRPDLTRNVCRALGVMPQIALSDVA
>A0A4V2UQR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuritortus calidifontis|TrEMBL
MSERTFSIEFFPPKTDEGVVKLRETRRQLAQLKPKFFSVTFGAGGSTRDRTLETVLEIQG
EGLAAAPHLSCIGSTRANIREILEVYKSHGIRHIVALRGDLPSGVADPGEFRYANELVQF
IRQETGDWFEIEVAAYPETHPQARNYTDDLNNFKRKVEAGANAAITQYFFNADAYFNFVD
DCEALGIDIPIVPGIMPISNYSQLARFSAMCGAEIPRWLAKKLESYYDDTASIKAFGLDF
VTGMCDDLLTGGAPGLHFYTLNQAALTSALWQRLGL
>A0A2G6TI93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 9|TrEMBL
MKVTEHIENAKGNTLFSFELIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
LMALRGDAMKDEQSFVPKVGGNKFAIDLVRQINDLNCGKYLHEVMDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFKFVEKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQIF
>A0A220WL61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. vignicola|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAPDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGVEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A6L8LFK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobius mangrovi|TrEMBL
MTVPAVSFEFFPPQNLEASFRLWDTVQVLAPLGPRFVSVTYGAGGTTRDLTRDAVATIHK
HSGLKVAAHLTCVDASREETLAIADEFAAAGVTDIVALRGDPPKGSGSFQPHPDGFASSI
ELIEALAEKGKFTIRVGAYPEKHPESPDHQADIDWLKRKFDAGADEALTQFFFEADTFFR
FRDACEKAGIDKPIIPGILPIENFKGARNFAKRCGTSVPDWVIEAFEKAERDGRQDLLAT
ALCTELCTDLIEGGVENLHFYTLNRPELTRDVCHALGVTPKTQLENVA
>A0A172DCF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capra hircus|TrEMBL
PIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVA
>A0A6N8S6D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella kummerowiae|TrEMBL
MNPATASLSRKDIRLSFEFFPPKSAEAEGQLWETAIALSAYAPGFMSVTYGAGGSTKAPT
LATVRQLLTMGLPAASHLTCVGATKEEVHAVVAEFQAVGVKHFVALRGDPPGGVGAAYQP
HPDGYANAAELTAGLHGLADFEISVSAYPEKHPQSADVAADIDMLKRKVDAGATRALTQF
FFENDDFERYLERVRKAGITIPVVPGILPVHNLAQVQKFAGLCGASVPGWLADRLGPVDD
RPQERAAVAVELAIRQVSDLIAHGISEFHFYTMNRATMVSAVCDGVGFARIDRQRATGAA
A
>A0A2S0JW31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sphaericus|TrEMBL
MGLLEKLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADVIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLEEI
LLTVEEQANVLLAGNPDGLLLETYYDFEELSATLKMLRSKTELPIIAQVSMHEPGVLQNG
MTLNQALHELQALGADVVGVNCRLGPHHTIQAFEGVELPDKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVALRDQGVRLIGGCCGTTPKHIAAAKKYLEELTPVEAKYTKPEKVEI
VREAEPATYEPLHEKVKRERSVIVELDTPRHLEIDGFIQGAKKLYEAGADVVMMADNSLA
SPRISNVAMGALLKETHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKIVEIYEATKHLDAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSDDALSRMKACGEDKERSTLEGIAIAKELVEVAAEYFNGIYLITPFLRYDMTLELMKF
IGQLDEQKKGVSIDG
>A0A7U9KND0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia liquefaciens FK01|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLDAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGSGKPDMYATDLVTLLKDVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAA
>A0A7X1PHT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas piscis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAGYNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKVPSAPHLSCVGDSKDDLRDLLQQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VNFIREETGSHFHIEVAAYPEMHPQAHNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVQKLGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
TQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWDNLKLPR
>A0A1I1YJC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus catalpae|TrEMBL
MKNEMLKDKILNRQAGIITYGMTPPKSSHTPEKLAEISEKQYDRLKDLDIDGLILYDVQD
EADRTDEERPFPYLEALDPTVYSKNYLNYWKVPKIIYRVVGNNSEDNFTNWLKQNAEEDR
FSVFVGTSSSNQQTTMKLPEAYELSRKLNDRLMLGGVVIPERHMKKNDEHLRIRDKVDGG
CKFFISQATFNVEASKNMLSDYYYYCQEQGIETVPILFNLAPCGSQKTLEFMKWLGISIP
KWLENDLLKSTDILDKSTTLALKIFEELFEFGIEKGIPIGCSIESVSTRKVEIEASVQLV
KDIKKVIDRKLGVHAIV
>A0A1Q2YCQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pichia membranifaciens|TrEMBL
MRNLYARLGRMSLLDQFPPEIQNDDDTVKEIGVDVLVKMIDQIYERKGNHIKGIHFYTLN
LEKSIAHIINKSKYLSKVVAKKEVELEQEESSSDEEIDDSITSAKRAAYADRFSTTNKVI
SDAKAVHNVRMTTSPSSQLKKLISISAGHGVLGKDATWDDFPNGRFGDSRSPAYGEIDGY
GPSLKVSSTRAYELWGYPTKKEDISKLFINYLLKKLDCLPWSELSLSPETSLIQEELINL
NEKFYFTVASQPAVNCTTSKDKILGWGPSNGFIYQKAFVEMFVSKKEWNENLLPKLNACG
SLVSYYYADSKKEFKTNLPFNASNCVTWGVFPNREILQTTIVEEESFKAWTEEAFEIWKE
WKLLYPKNSDSAKLIDSILNDYYLVTVLHHDYPNEAALWELLLED
>A0A3B0BEG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces klenkii|TrEMBL
MDSRTASPGGATGLLLEDFSLEMTGKDVPDLHEARHYLPAGTRVNVTFLGNEDLPMRLTA
ARAVKDLGFEPVPHLSARRMPSRAAFEEFLSRLRADGTSGQVFAVGGDPAVPEGPYGEAL
ALIRSGLLERYGVQQVGICGYPEGHPAITGPELWSALERKAAALAERGIPGHVITQFGFD
PGPVLGWIGELRDRGIHLPVRVGVPGPAGVRRLLGYAARFGVGTSAGIARKYGLSLTHLM
GTAGPDRFLRALSEGYDPQRHGTVKLHFYTFGGLRATAEWVAGFRATIPAAS
>V0AAE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 907713|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5J6P9Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrio sp. KY-GH-1|TrEMBL
MSDSQLRLSFEFFPAKTAEGKEKLIKVRDELNFFNPDFFSVTYGAGGSTRDNTKGLVTKF
KADGISTAPHLSFGGDDDDSIKQLIQEYKDAGVDRIVALRGDMPSGVGGGMQLVYANELV
AFIRKHFGEHFHLEVAAYPEIHPQAKSYSDDVRYLKGKFDAGANSAITQYFFNPDAYFFF
IDQCHKAGITQPIFPGIMPIINYKNLIRFSDACGAEIPRWLRKALENYGDDEASLKAFGV
ELISELCETLLENDAPGLHFYTMNQTEPTAQIVRNLGLIPVE
>A0A3M3XWP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. primulae|TrEMBL
MSCVGDSKEDLRSLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDLVAFIREETGS
HFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFNFVERVEKMGV
SIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEDVITQMCER
LLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1Z9EW28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium TMED138|TrEMBL
MVVTQQVSYAKESFDLSFELFPPKTAESEAMLWQTVDELMGFDPTLITCTYGAGGSTQTK
TLEVLDGVLVRYPTVAVASHLTCVGRTTDQLREYLREAQQRGVTSIVALRGDPPQGETTF
TPIANGLHYAVELVALIKXXFPEXRILVAGYPETHQEAVSPXXDLEHLKEKCNAGGDTVV
TQLFYDXTDFFRFRDRCSSIGITKPIIPGLMPVTNFKQIKRIATLCKARLPXSFTHALEK
AGDDADAQFEAGVDYASKQAEELXSNGIPGMHLYVLNKSPAAIRVLEQVGMTRP
>A0A5C6RS53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vicingus serpentipes|TrEMBL
MKVIEHLNQAKKPLISFEILPPLKGKSIQSIYDSIDPLMEFKPSFINVTYHREEFVYKKR
EKGYLEKISIKKRPGTVGICAAIMNKYQVDAIPHIICGGFTKEETENALIDLNFLGIDNV
LALRGDPIKTETNFVPEEGGHAYAVDLVKQIVGLNKGEYFDEDLLNATPTDFCIGVAGYP
EKHFESPSFKNDLKHLKQKVDAGAEYITTQLFYDNEKFKSFVIACREAGINVPIIPGLKP
ISNKNQLLSLSKFFHIDIPDDLVEAIEACKNDNAVRQVGIEWAIEQSKDLIDFGVPCIHY
YTMGKSISTREIVKAIY
>A0A4V1J0S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syncephalis pseudoplumigaleata|TrEMBL
MKITQKLHKAEAEKRPYWSFEYFPPKTQQGLLNLYDRMERMYRLGPEFIDVTWGAGGSTS
DLTLDICGTAQTVYGLETCMHLTCTCMPREKVDMALRECKNNGIQNILALRGDPPRGQDT
WEACEGGFVHAADLVRYIRDQYGDYFCIGVAGYPEGHTECESKELDLQYLKEKVDAGADY
IVTQLFYDTDLFLDWVDKCRAIGIQCPILPGIMPIQNFNGFKRMTTLSQTAVPQFIYDSL
EPIKEDDQAVKDYGITLAIDMCRQMAAKGISGFHFYTMNLERSIRLILEGLGWVAPVEIT
RPLPWNPSKSKKREKEGVRPIFWKNRARSYIQRTESWDEFPNGRWGDSSSPAFGELDGYG
ASIKQSRQDAVKLWQHPTTVDEVAALFSRYCRGELSALPWSEQQPNIETDVIREHLVGIN
QRGYLTINSQPSVNGVKSSDRMFGWGPKNGYVYQK
>A0A8H7Q9I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Umbelopsis vinacea|TrEMBL
MKIIDKIKKAEEEGRIYWSFEYFPPKTPLGVQNLYDRIERMKRFGPEFIDVTWGAGGTSA
DLTTEIVSTAQAVYGIETMMHLTCTNMPKEKVDFALKSAKECGCQNILALRGDPPHGQEN
WTAVEGGFSNAIDLVKYIRQEYGDYFGIAVAGHPEGHIDNPDKEEDLRHLKAKVDAGADL
IVTQLFYDVDTFLNFVEQARAIGITCPILPGIFPIQNYNGLKRVISFNNNNVPQKIWDDL
ESIKDDDAAVKEYGIELSMQFINKFIEAGIKGVHFYTFNLERSTRIILERMGFVPQQATV
KPLPWAPSLHQKRTKENVRPIFWKNRTKSYIKRTESWDEFPNGRWGDSRSPAFGELDGYG
VSLKHPKNECLEMWNHPTSVEDVSALFAKYCTGDLAALPWCAQQLDPESEVIRQRLAAIN
AQGFLTINSQPAVNGAKSSDKVHGWGPSNGYVYQKAYLEFFVSPEQLDSLIAKIGAKKDI
TYYAVNSQGDLKTNNNNHGPNAVTWGVFPSKEIVQPTIVDATAFMAWKEEAFELWSQWAN
LYEADSASTQLLKSIKSQWYLINIVDNNFVVSDGIWKLFEVDASDDLSSKVSELNVADR
>E2ZMC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium cf. prausnitzii KLE1255|TrEMBL
MKDVREILKKRPLLFDGGMGTYYKAKPGQECEQANLLDPDGILTVHRAYLEAGADAIKTN
TFGLPRMAAAQNPMWEAMADEGWKLAAQAAAKTSAAVFADLGPAPDTEALPAAQIYTALA
ERFAALGAKNFLFETLSSDAGVAEAARQIKEAVPDAFVLVSFAVLPDGYTREGRHCAELV
RSMTACGAVDAVGLNCVSAPGAMRALVQQLGETKLPLAVMPNAGYPVVTRTRVQYQGKPE
YFARELARLAAEGVRILGGCCGTTPAHIAALRAALDALPETLPAAPAAAVSTAAKPEVEK
DDAFLRKLNAGKKVIAIELDSPKDADMTGYLDGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGLNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPLTVFGALNLNARNFDVELRRAQEKLQNGMSGFL
TQPVLSAQAVVNLKKTRETLGEKAKILAGIMPVVSQRNAIFMENEVNGIHVDAEIIERFA
GLDRAQGEELGLEVSVKAAQAAAPYADGFYLMTPFNRIALMERLIARLKDEGIAD
>A0A7H8KSX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora sp. NA04385|TrEMBL
MALGIPTTRNDRAQTVRDLLAAGDRSFSFEFMPPRNEEAERKLWDAIRRVECLEPNFVCM
TYGAGGSSRGRTVDLVGRIATETTLTPVAHLTAVDHSVAELRNIIGQYADQNVRNVLAVR
GDPPGDPLGEWVRHPEGVTYAAELVELIKGIGDFCVGVAAFPQMHPRSENWDEDIRHFVA
KCRAGADYAITQMFFEVEDYLRLRDRVAAAGCETPIIPEIMPVTNSRQLVRFPQLSGSAF
PDDFRRKLEAVVDDPAAVRAVGLEHATTMAERLLAEGAPGLHFITLNHSTSTLEIYQNLG
LHTR
>A0A4V6X4D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Martelella alba|TrEMBL
MSFFHANQREALNQNLVELQGRINVSFEFFPPRTSEMEQTLWHSIDRLSSLKPTFVSVTY
GANSGERNRTHTIIKEIKERTGLESAPHLTCIDATLEELRLIAEDYWQSGIRHIVALRGD
LPPGGGKPAMYAVDLVALLRKVGDFDISVAAYPEVHPEAKSAQADLINLKKKVEAGANRA
ITQFFFDVESYLRFRDRCVAAGIETEIVPGILPVSNFKQMQRFAAMTNVKVPNWMTRMFE
GLDNDPETRQLVGASIAMDMVKILSREGVKDFHFYTLNRADLTYAICHSLGVRPQSAAAD
RPSPAQG
>A0A1G9MMM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces wuyuanensis|TrEMBL
MSALGDLISADEPTFSFEFFPPRTEAGQRSLLRAIRRIEALTPSFVSVTYGAGGSSRDRT
VEVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGIRDVLVLRGDPPGSPRGPWT
PHPQGFDYAHQLVSLVRGLGDFSVGVAAFPECHPRSPDRDSDIRHFVAKCRAGADYAITQ
MFFHVEDYLRFRDRVEAAGCETPIIPEIMPATDVRQIRRFSELSDAAFPEDLAHRLEAAR
QDPGTAHRIGVEYATGMALRLLAEGAPGLHYITLNRSDAAADIHRNVMSSRSSDVLSGHR
>A0A1U7HA37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrococcus rivularis NIES-593|TrEMBL
MTTRFRRAVQDREFLITAEVTPPKGGNPVRMLEMAKLLKDRVHALNITDGSRAVVRMSSI
AASVILLQHGIEPICQIACRDRNCIGLEADLMGAHALGIRTILALTGDPVKAGDRKESRS
VFELESVRLLKLIANLNSGLDFKNQPLPDEPLDLFAGAAVDPQLKSWSSLQQRFDRKVEA
GAQFFQSQLITDFERLDKFMNQIAAGSNKPILAGIFLLKSAKNAQFINKNVPGVQIPEDI
IKRLADAPDPLQEGVNIAAEQVRLAKQLCQGVHLMAVKREDLIPQILDLAGIPPIEKPEL
NPV
>A0A512RHV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga cymbidii|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPSYINVTYHRSEHMFKKR
ADGSFDKVEIRKRPGTVGICAAIMNHYTVDAVPHLICGGFSKEETENALIDLNFLGIDNV
LVLRGDAPKNETFFEPHPNGHRYAIDLLQQVAHMNNGIYLEEDLMGGVKTKFCIGVAGYP
EKHFEAPNMATDMKYLQRKVEAGADYIVTQMFFDNQKFFDFVAKCREAGIKVPIIPGLKP
LTTKKQLTILPRTFHVDMPDDLAVEALKCKTDKDVEQAGTEWLIQQSKELKAAGVPVLHY
YTLGKPHVIRKVVEAIR
>A0A0H0YJL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus casei|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNVALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDLEPVAHLPAAQLTRAQVDAELRGFQEAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQRGDFNVVAACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYRFRERTELAGIHVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRITTATKTIRNA
>A0A1H3YD60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachidicoccus rhizosphaerae|TrEMBL
MFLDKIKSGQSGILTYGITPPKEGTTPEKVQEIAEKTMARIIPLDIDALVVYDVQDESAR
TAAERPFPFMNALDPFQFSKDYLQRITAPKIIYRPAGKFSAAELTDWLADIHSHQFHPVF
VGVPAADFEVKITLAEAYQLWQQYKDNSVLGAVTIPERHAVLKDEDKRILEKAKGGVSFF
ITQCVFNLDYAKKMVEDLCQTCTEQGIPAPALIFTLTACGSVKTLRFMEWLGIHIPDALK
EQLVASDNMLEDSLKACLDNAAELIAFCSAKCVPFGFNIESLAIRKDEIQASIDLVSKIG
AMLNRPNNNATAAVLTTSKEN
>M2N4U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Baudoinia panamericana (strain UAMH 10762)|TrEMBL
MDKITDKIAALPPDANYFSLEFFPPKTQQGFSNLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRRLVDEALEQAKVLGVRNILALRGDPPRSDE
YRDDNSPDAVEDDSNRDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDLSHPEHQSVEH
DLPYLVEKTKAGADFIMTQLFYDVEAYQQYERRLREHESGVFKTIQIIPGLMPVQSYQIL
RRTTKLSHASLPNDVLKRLEAVKGDDEAVKRVGIDILCEAVEKMKGMENPGPRGFHFYTL
NLEKVVTQILERASLVPPATPVVISLDENGLPEQAVAEEETDGFLMVEDAKKRHHRRQSS
ARNSHPRNRVVVPRDRASSTSSTRTSAAYEAPDDEAGVPKDQINNRANTLAISEGEGALG
REATWDDYPNGRWGDVRSPAYGEIDGYGVSLHATIPEAKRLWGFPTTENDIADIFRKHLE
GKINAIPWSEEALLPETLTIKKQLLGLVEKGWWSVASQPAVNGVRSTDSVFGWGPKNGFV
FQKPFVELFLPAADWERLRQKLMENEQVTYFAGSAAGDFGSSDEHSVNPVTWGTFTGKEI
ITPTIIEAVSFKAWLEEAFGIWAEWQRVYKPASESSKLLERVRRNYWLVNVIHHGYLEEN
ALWDLLLGA
>A0A6A7K540|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalibaculum sporogenes|TrEMBL
MTVEKHSFKDAVLDKDKFSITWELVPGRGSNEVDQQNVIKLAQQASLDPRINAITLTDNP
SGKPAIHPFGLAEEVKNLGVETLIHFTCKDKNRNDIESELYALDRAGLPNLLVMTGDYTT
EGYNGRPKPVFDLDSVQTIKFIEDMNNGLEVKAHKKTKTFPKTDFFEGAVVSPFKALESE
VMTQYYKMHQKVDVGAKYIITQVGWDARKFDELRKYVDKYELNTPLIGNIYVLSMPVARM
MNKSIIPGAVVTDKLLSDLDAEKKEFDNNKERQLLRSAKLFAVLKGLKYDGVTIAGHGLK
YEEIKFILDKGEELYSNWQELVKEFDYPEDNGFYYFEKDEATGLNTTTPVDRKNTGSKSN
SLFYWSFGLVHKFALSEGAPLYPMIKFFAKGIDKSVLNKPFTYFEYYTKTITNECRFCGD
CVMHELAFQCPMSQCAKHQRNGACGGGKDGWCEVYPGEKRCIYVNMYEKYKHSGKEYSMK
NRYAPPADWSLYKTSSWLNFFNERDYNYRDKE
>A0A837DBJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora viridis|TrEMBL
MTTKSEVADSRRPRGLADLVGNISYEVMPFKSVERAVLADVPTSIPLTVTVTEAKGIDTT
LDFTERLMRHGYTVTPHLAARQFVDDNHVREVIDRLQTAGVNSVFIVGGDAPKPAGRFHS
AYMLLQAMQELGHPFSEVGIGGYPEGHANIPQSDIELALKQKAPLATRILTQICFDANTT
ANWAAGVAKSGIDLPIYVGMPGPVNRQKLVRISAGIGLGQSARFLQKQQNLLWRFLLPGG
YNPTKLARRLGSAVPKVRSNIRGLHIFTFNEIQKTEQWRRKLLASVSEKDKR
>A0A1S0YQ37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC074A01|TrEMBL
MRGTLPSTRLSASAPLDSLGEAPVTPQRRARTALSFELIPPRHDADSGKIDELIAGLAAY
NPDYVAVTSSRRSDWLTGTAALIARVAETTNLRPIAHLACTAGTREELATWIRTLIDAGV
RGFLALRGDLPETGMPAHYLQHATDLLNLIQDVEDEEAFRLAAGKLALSVACYPSGHAES
KNFDEDLDVLLAKQRLGADFAITQLFFNAQDYLDFVEVARLAGVRIPLIPGIMPMTSLKR
VQRMGELSGIAVPECVTRTLAQATTPEEEYELGMQMSAQLANTILDAGTGGLHVYTHNNL
AVTQDLLDRIGIVQPAGHSLI
>A0A2G0WJU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ICMP 460|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYHPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVHIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A356Z5C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas sp|TrEMBL
MKIIEMYKSQRPLLSLEIFPPRIDYPLETIFKTLDKLKLINPGYISVTYGAGGSNRDRTV
EITTRIKQDYQIESQAHLTCVSHTRREVNAILDELGHQGIENIMALRGDLPEDGSFNIEK
QEYRYACQLIEDIKGRDNFGIAAAAHMEGHPECSTLREDLLNLKHKVDVGVDFLITQLFF
DNRIYYDFLEKCRRTGINCPIVPGVMPVLNARQIRRIIYL
>A0A1H9CL60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp. YR412|TrEMBL
MLDDNLRASRQTADQRPDLQISFEFFPPKTDVMEEKFWDSVHKLAPLKPRFVSVTYGAGG
STRERTLRMVSRIKAETGVDAAAHLTCVGATRDEVDAVVRDFQQAGVNRIVALRGDPPEG
VGQPFTPHPEGYQNAADLVGGLRRIGDFDISVAAYPEKHPQSPDMAFEIDNLKRKIDAGA
NRAITQMFFTNSDYLRYVERARAAGITAPIVPGIQPIHSFKQIASFAARCGTSIPAWLAE
RFDGLDDEPETHALVASAVAAEQVTELLDEGVTEFHIYTHNRSPLALALARILGRRPEAD
AGL
>A0A4Q5J018|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides iriomotensis|TrEMBL
MALGLPSRMPGGASTVRELIAAGERSFSFEFFPPKDAEGERQLWRTLRELEPLNPTFVSV
TYGAGGSTRDRTVGITAQIAHDTSMTPLAHLTCVDHSVATLRSVIGSYAGAGVRNVLALR
GDPAGGPRAPFEPHPEGLRYAVELVELTKSLGDFCVGVAAFPELHPSAESADADARVLAA
KARAGADFAITQLFFRPDDYFRLVDRVSALGVDIPIIPGIMPITNLAQVTRMAELSGAAL
PDEVVERVARFEGDPAAVRAEGIRVATELCDTLLAGGAPGLHFYTLNRSKATREIFSGLR
TAVG
>D3PDD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deferribacter desulfuricans (strain DSM 14783 / JCM 11476 / NBRC 101012 / SSM1)|TrEMBL
MKISRILSEKDFVISFEFFPPKKVENEKILFNTIEVLKGYNPDFVSVTYGAGGSTKDKTI
DWTIKIKEQYNLNVMMHLTCVTSSRDDVDEILTVLQEHNIDNILALRGDIPKDQENIKAD
FKYAYQLVEYIKNKNFFSIGVAGYPEGHIESASLEKDIEFLKMKVDAGADFIITQLFFDN
KYFFDFLDRAEKIGINVPILPGIMPVINLNQVKRFTEMCGATVPDSLIKKLENKSEEDMF
KIGIEYAINQCKELIEANVKGLHFYTLNKYNATTNILEGLGYVPKSL
>A0A0Q5Q7V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Leaf179|TrEMBL
MEYGPCGGVGFDGSCEIDPDHRCAFLHRPTVPWTGIDRSTLPAPAPRTAGALATLDALGT
RPWVVADLPARALSVASIDACAAVLAGEVDAVLAGDAGSARVQFPPAYRASLVQRRGLRV
WTGLNMRDRNRVAIEGELAALAVEGVAGVHCVTGDHTATGHRPDAAPVFDLDSTEATALA
RAAGHVVSVAASPAAPPVERRAARLREKLRAGADVCFVNHAGGATPVRRFIDEVAAEAMY
IPCVPMVVDHASAALLESFTTLVLPEDFLSRVRDAHDPRAEGIALAVALAEDMLAIPGVV
GVNLSGGREGAEESFAEAMAEVARRLR
>A0A2T1DP22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phormidesmis priestleyi ULC007|TrEMBL
MITFNRLQTLFTTNPFHQWSSLLTTGHFKSAKTRSFSRLQTLLAAGHFVVSAELTPPRHY
KTEAFTTNAEKIAAYIDLVQINDNAMAQARLSTLVAAQLMQRSGIESVVQLTLRHRNRIA
LQSDLLGLAASDIRNVIVLGGYPCSAGSDPDAKDATDLSTLDAIAALTRLTTQGQLFNGQ
QIAPPPDFYVGSIATSAVTDLEASMAQLTDKIDRGAKFIQLQATFELAETERWMAEVRAR
NLHKRAHFLAALYPFNGLKSLERLSQIPGLSIPESLMMRISQSRDRRSESLKANLELVEG
IRAIEGIRGLHFRAIPPREWLPKISELIRTVSQRVAIGELKVQNPLEG
>A0A373NR34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF31-8BH|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMENLPGTIDHLMKYKPEYISCTYGAGGGNVGANRE
VCQMIKKAGTVPVTHFTVIKNTKEGIKEQLDQYLAEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDMSATINMALSRNGCVMDSELCRLISRNWLFPN
PFAAKDADGKPFDMFYDDKIKRFKEEGIEYTIKQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A1F8XGI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium GWA2_57_13|TrEMBL
MKLCEIYSRPGPVFSFEFFPPKTAKGDEGLSDEIAVLKTLHPAFCSVTYGAAGSTRAKTV
ELVDRIHRECGLEVMCHLTVVGQSKDEIRSVLKRLMELGIDNIIALGGDPPQGVVDWEPH
PDGFHHSIELVREAVACRWFSIAVAGFPEVHPRAESRDFDLRYLKAKVDAGADVVITQLF
FDNEDYYRYVDDVRKLGVSVPIVPGILPVLSVPQARRFTVLCGSRIPPRLEQVLSRVEDD
DEGAVRLGIDYATEQCEGLLRFGVPGIHFYCLNKSRSVKAIFANLGL
>A0A1T2B314|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioclava sp. DLFJ4-1|TrEMBL
MTTPKVSFEFFPPKTLDASFRLWETAQVLAPLKPEFTSVTYGAGGTTRKLTHEAVGTIHK
NYGLNVAAHLTCVEATKAETMEIVDAYAEVGVTEIVALRGDPPQGAKHFTPHPEGFASSV
ELIEALAEDGRFTIRAGAYPEPHPDAADAMADVRWLKRKVEAGATSAITQFFFEPETFFR
FRDACEKEGIDAKIIPGILPIQSWKGAKKFAQSCGTSIPAWVEEAFEAAIRDGREHLLAT
ALCTELCDKLIEGGVEDLHFYTLNRPGLTRDVCHALGVTPDTVLEKVA
>A0A7V8Z1N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MKNFRELLETDDVYVFDGAVGTRLYDKGVYINRSYDELNLISPDLVREVHEEYVRAGADI
IETNSFGATRHKLQPYGLEDKLRDINIAAARLAREAAGDKAYVAGAIGPLGLRIEPFGPT
SFDEAKDLFKEQAEALLEGGVDLFILETFSDLPLIEQAIRAVKEVCDLPVVAQMTIQMDG
RTTFGTSPETFTVKLDELGADIIGLNCGMGPNHVLTALEKMRELTGRKLSAQPNAGLPRD
VQGRQFYMGSPEYMATFAKRFVQAGAKFVGGCCGTTPTHIKLIADSIRSISPRQSQNFVR
TNLAAVTELKPSDVQVVAPEERSNWSRKVARGEFVTSVEVLPPKGCDAQKTLDSIRLLKD
AGVDAVNIPDGPRAQTRMSAQATAVLVERNIGIEAVLHYCCRDRNLLGMMSDLLGAAALG
LHNLLIITGDPPKMGPYPDATAVFDIDAIGLTNMVNKLNHGLDLGNNPIGLPTAFSIGVG
VNPGAVNLEEEIRRFEWKVEAGAEYAITQPVFDTEQLRSFLDKISHVKIPIVAGIWPLVS
FRNAEFLHNEVPGVNVTPEILETMRIASDKSKEDAREAGIAIARESLNEVRDVIAGVQVS
APFGNVKYALQVFDVLEDFKSSSLSVTKG
>A0A010ITA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 1542444|TrEMBL
MTLADRVHSDHDIAPLEASKSYSDSIEKVLHFSGKARDIQDFERFLEQAQAANIQNLLLL
TGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLH
KKIKAGADFIITQLGYDIEALEQAKSFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGI
VITPHMLKVLAEEKQAGHTDRVYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIE
QYRHLELKALEELWNSLWQVTSGKEFSPEISRFSRQPTSKQLIKYHQLHVMHEAMFGSKI
AKGVGRFIFKASFWENALIAKLLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGL
ANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQTEILKEKLIPTVSLETRGTSSWKNWY
LATEA
>A0A317I6N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MEPFKNLLESDGIHVVDGAMGTMLYAKGVYINRCYDELNLSNPDLVREIHTEYIRAGADI
IETNTFGATAHKLQQYGLEANLHEINAIAAKIAREAAGDRSYVAGAIGPLGLRIEPYGPT
SFDEAKELFKAQAVGLLEGGVDLFVLETFSDVSEIRQAIRAVRELCDLPIIAQMTIMTDG
NTLFGTTPELFTERLDQWGADVIGLNCGVGPAIILNALEKMREVTKKKLSAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRFIQSGAKFIGGCCGTTPAHIKLISDAVRAASPRAQRVAFS
SSSSAQVDEIKAPDIQVVPAEERSKWGRKIALGEFVTSVEVLPPRGVETQKTLDSIRLLK
DAGVDGVNIPDGARAQSRMSALATAVLVEQQIGIESVLHYCCRDRNLLGMMSDLLGAAAL
GLRNILVITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGQPTAFCIGV
GVNPGAINLDEEIKRFEWKVEAGAQYAITQPVFDTDQLRDFLKRIEHVRIPVVAGIWPLV
SYRNAEFLHNEVPGVRVTPSIMERMRDASNISKEAGREEGLKIARESLLEVRDVIQGVQV
SAPFGNVKYALEVFGALDDFGAANELSSVEGISIN
>A0A6N9A1X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MPDLRSLLSDGRVHVLDGAMGTMLYDRGVFVNVCYDELNATRPGLVEDVHGEYVRAGAEI
IETNTFGANPVKLSSFRLEERTGELNRLAAEIAVRAAGGRAAVAGAIGPLGIRIEPLGPT
SREEARDYFGRQVDGLLEGGVDGFILETFADLVELEQAFRAVRDRCDLPVIVQVTVGEDR
KTTTGASARQAALAAMEWGADAVGLNCSVGPAVVRDGLEQMAEITTLPLAAQPNAGLPRA
VGDRKMYLTRPDYTARYARHLIDAGARLLGGCCGTTPDHIRLISERVAAIQPRKTSVRVT
RDVLPHAAAHPAPPLAERSGLGRRLATGEFVKSVRVLPPRGWDTTALVEDCRALAAAGAH
VIAIHEDRGGARLDVLATASVIARTCPGAEPLVHYTCRDRKLPRMMSDLLGAAATGLHNL
LLLTGDPPGPGPYPDYRSVVDIDSIGLTNVVTGLNTGVDPSGSEIGGSAGLVTGVALNHT
ARDRERELGRFHWKVDAGADFAVTQPVFDAAQLRGFLAEIEQRVPVIAGVVPLESARQAE
FLQNEVPGVHVPDRVVERMRRAQARGAGRAAAEGVEIAREILGELQGEVAGIQIAANRDA
VEAVLGSTP
>A0A7X3TQY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MDNPTVPMQPFLAALHHRPLLADGALGSYLFALTGRVSEQNHLYEAFNLTRPALVRQLHL
EYLQAGAQCLTSNSFAANATYPSAVSIAELNAAAVRLAREAIDQYCQQAQYSDPLFVLGS
LGPPLPAAQAPRTASDLYRAQIEALVEGGVDALLLETFTCLDQVAALLELLQDLDNPVPV
IVQMALHQRDGTWEQAPQAYIQTAAALGADVVGINCCALAEARAFLDAAQECASVRDGQV
QLAVMPNGGEFRRVGHRYLTGVNPECMGRFAREMAHKGVRLIGGCCEVHPSHIHEMHNYL
HGLAAGERIVPLARTPDQQPIDATAKRRNGPFSRKLIDGQFAVSVEMLPPRGTGGLKARL
AFIAELAASGLADALDITDGSRGIPLMPPGDFIHLIRRRLHWERDRLELIPHCTSRDLNV
MGLQSRLIGYWANRIHNVLFITGDPPKMAPTYPRSTAVFDLDSAALIRYTHAFLNAGLDF
GGQPLGTHRDPRTHFTIGTGCEPEALDLQREWERLAHKIDAGADYVMTQPTFDRKALAPL
TTYRAQVPIIVGVMVLRGLEHARRIAEVPGVIVPEAIFAKLSAYADPADQTKAGVELAAE
QVRQVRAEGWSGLYLMSPAGHQPVLEVLKRGLG
>A0A2S7QR35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rutstroemia sp. NJR-2017a BBW|TrEMBL
MHVKDMLSDAQRAGTPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKDKIDEALRNAYKAGCTNILALRGDPPREKEK
WVATEEGFRYAKDLVRYIRQTYGNHFDIGVAGYPEGCDDQDDPELLLDHLKEKVDAGATF
IVTQMFYDVDNFIEWLGKVKAKGINAVIIPGIMPINTYASFLRRCNHMGCRIPPKWSAAL
EEVKNDDAAVRNIGKDLVVEMCRQILNAGVNHLHFYTMNLAQATRMVLEDLGLTPSSNRP
LKQALPWRQSLGLGRRAEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNRKLWGEPASVRDIAEIFVRYLQNDIESLPWSEAPITSEADAIKADLIG
LNYRGFLTINSQPAVDGAKSSDPVYGWGPTNGYVYQKAYLELLVSPDVIEELINRIQRDP
DLTFYAVNKAGELRSNASNDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHSSLSPSRQLIESVMGSWYLVNIVHNDFHKSHGLFPLFDGLTVENIDKPFESVAQDG
ETNGTTNGAEAAPLKNGDANGHAGFNGIRLYIIAFNGLA
>S0ESH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthonomonas calidirosea (strain DSM 23976 / ICMP 18418 / T49)|TrEMBL
MHICDIFAAHRTTFSFEFFPPHTPKGWEQLFKTIEDLMPLRPSFVSVTYGAGGSTREKTH
ELVVRIKEQIGCEPIPHLTCVCHTEEEIHAILQRYAAHGISNIMALSGDIPRDKPHHDRT
KDAFRYAAELVRFIRKFNESGLHPDPRGFGIGVAGYPEGHPDTPNRLKEMDYLKAKVDAG
ANYIVTQLFFDNRDFYDFRERCELAGIHVPIIAGIMPITSISNMERIAELARGSRIPAGL
LRAVRRCGDNEEYVRRVGIQWATEQCRDLLDNHVRGIHFYTLNQSSATREIYANLGARDS
SALET
>A0A512MDB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevifollis gellanilyticus|TrEMBL
MHIRDILQPSRSTFSFEFFPANTTEGRDRLNDTITQLSGCQPDFVSITYGAGGSTRDATR
QLVEHVRQSTPLNPVPHFTCVNHQRQDIDSILGHYAGLGISNILALRGDAPRGSTSYDHG
KDFCVNGADLVRHIQTFNESGVHFDKRGFGIGVAGFPEGHPGTPNRVLEMDYLKAKIDAG
ADYICTQLFFDNHYFHDFRERCDLAGIRVPILAGILPVTSMAGLKRMAELSGGTNVPARL
LKSLSRVQDDPAAVIEIGLHHATEQCSELLYHGVAGIHFYTLNQAAPTLEILKRLGRAPA
KAAA
>A0A1H3F5R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas halophila|TrEMBL
MQSQKKFSPTFSFEFFPPQTPEGMEKLRATRAQLARFDPKFFSVTFGAGGSTRERTLETV
LEIQAEGYPVAPHLSCIGSTRENILAILEKYQSLGISHIVALRGDLPSGMARAGEFRYAN
ELVAFIRQTFGQAFRIEVAAYPEYHPQARSAQEDFANFRRKVEAGADAAITQFFYNADAY
FYFVDMCEAANITIPIVPGIMPISKFSQLTRFSDGCGAEIPRWIRRKLEGFGDDTASIQA
FGLDVVTAMCARLLEAGAPGLHFYTLNSAVLSTKIWQRLDL
>A0A1F5IZB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium RIFCSPHIGHO2_12_FULL_53_21|TrEMBL
MRLPEYFKYGEKGPVISFEIFPPKTEKGMENLGMVIEELTGIGPDFITVTYGAMGSARER
TLEIASLIKNRFGVETACHLTCVGSSREELDRLLIQIYESGIENIVAIRGDVPSGAQEFI
PPPDSYKYGYELVRHIRQFEEDRLNRRYFGIAVGGYPEKHTEAPDMETDIKNLKHKVDAG
ADIVITQLFFDNRHYFDFVERARSHGIKTPIIPGLMPILSVKQIERITSMCGATIPSDLR
KRLDACKDDNEKARAIGIAQCIDQSKELLARGAPGIHFYVLNKSDHMKEIIGALPVSRFK
YSGGKFAANIP
>A0A2T8HVQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararhodobacter oceanensis|TrEMBL
MPAPRVSFEFFPPKTLDASFRLWETVHMLAPLKPEFVSVTYGAGGTTRKLTHDAVTTIGK
EFGLKVAAHLTCVDATKAETLEIAQNYAKAGVNDIVALRGDPPKGQGGFTPHPEGFADSV
ALIEALRGAGDFTLRVGAYPEPHPDAADSAADITWLKRKFEAGADSAITQFFFEVETFLR
FRDAAEKAGIDASKITPGIMPIENWSGIRRFALAAGTSVPAWLDDAYGKAARDGREDLLS
TALCTEMCDTLRNEGVEALHFYTLNRPALTRDVCFALGVTPEVALQNVA
>A0A220UI91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella bicestrii|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETNLVAAPHLTLVDASDEELLDLAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAADLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPSWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPKAV
>A0A533SGI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
ILADGAMGTMLHKRGIGFDICFDELNLVNPAVVGDIHREYIEAGANIIQTNTFGGNRYKL
EQHGLEDKLVEINSAGVELARRVVWASFKKVLIAGDVGPLGVRLAPFGRVQPEQARQAFA
EQITALANAGVDLLIIETMTDLYEVREAIAASKQVASYLPIIASMTFTRDDRTLLGDDPV
KVARAMHGFGADVIGVNCSGGPNQLLRILKAMREAVPEGRFSVMPNAGWPQQVGGRIMYP
AEPEYFGEYALSLWNAGATILGGCCGTTPEHIAAMAHTLENAAERVDSDREVDVDNDRDD
PQPTSAQPTQLGQKLADGQFVVAVEMDPPRGFSTHKLLAGASLLAEAGADVINVADSPMA
RMRMSPWAVCSLLQRRIGVETVLHFPTRGRNLLRVQGDLLASHALEVRNVFVVMGDPTAI
GDYPDAADNFDLVPSGLIKLIKQG
>A0A6L4Y9L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MAKSFKEALESGKFVVTAEVGPPKGTDIEEMLHHIDLLKDKVDGLNVTDNQSSVMRLSSI
SVSHIIKEKGGEPILQMTCRDRNRLALESDLISANILGINTVLCLTGDYITVGDHVEAMP
VFDLDSVLLLKTVRLLESGKDLGGNELKGAARFCAGAIVTPEANPIEPQLLKFEKKIKAG
AEFFQTQAIYDLDNFKKFMKYARQFNVKILAGIVLLVSSGMAKYMNANVPGIFVPKDLID
EMASAEKGKALEKGIEIAGRMIKTLKDENICDGVHIMAIGKEGKVPDILAAAGLA
>A0A4R1ZWS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. BK033|TrEMBL
MKPDLRTKLKQRILTGDGAMGTYLYQMGFPVGVSYEELNMTRPDVIEGVHRRYYEAGARV
IETNTFSANLVKLSKYGLEPDMEAINRAGVRISKAAAGEDAYVVGAIGSIRAGKLKDVRT
SEVSDAFERQLDALLVEGVDGILFETFYDFDEMRLALGLARKRTQLPVLCQFAVEDVGRT
QDGTGLLDAFALLKDEGADVVGFNCRSGPNGIMRAVESIGGPVELPLSIFPNAGIPDYVD
GKYKYSAGPDYFAETALQFADRGARIIGGCCGTTPEHIAAMARALEDYAPIGGAAAVAIA
APPEAEVIVIEAGAAEVVKNASGERADTPIVSEPSLVDTVKVRHTVIVELDPPRDLDIAK
FMAGAAAIKACGADAVTMADNSLAVTRMSNLALAALVKDRIGLRPLVHIACRDRNLIGTQ
SHLMGLDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMTKQLNDGIAFSGKPLK
QKAKFVVGAAFNPNVKHLDKAVQRLEKKIASGADYIMTQPVYDPALMEKIAEATKHLPVP
VFIGIMPLASGRNAEYLHNEVPGIQLPDEVRKRMAGLEGAAGRAEGVRISRELLDIAVGH
FKGIYFMTPFMFYEMAVELTEYVWAKTGVQRR
>A0A7Z0MWJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MSSKQAVSLEFFPPRDIAAQEKLVRSAKQLLALQPAYVSVTFGAGGSTRTGTADTVRLMQ
NLGCDAAPHLSCIGASRAELADILDTYRKQGIKRIVALRGDLPSGMGGDGGELHYASELV
AFIREHSGDWFHVEVAAYPEMHPQASGAQADLDHFVNKVQAGANSAITQYFFNADAYYDF
VDRAQARGVSIPVVPGIMPITNYTQLARFSNMCGAEIPRWIRLRLVDYGDDKASIKAFGV
DVISRLSQDLLDNGAPGLHFYTLNNAEVTMAVWKQLSLDG
>A0A7V9N5F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexia bacterium|TrEMBL
MTHPLLERLAAGPLLADGAIGTVLYAAGASLDESFDALNLSRPELVLDVHRAYLEAGADL
LETNTFGANRFKLEGFGLGGKVREINRKAVRLAREAREISGRTALVAGSVGPTGRTLAPF
GTIATEAVRAAFREQIDALLEGGVDLLVLETIGSLDEMVEAVGAAREACDLPIIASMTFA
EDGRTIGGSTPQEVAARLLDLGVAAIGANCSVGPQRLLPVAAALVRRVEEENGPGPVVSC
MPNAGWPAHVAGRVMYPSSAEYFAGFARRAAETGVRIIGGCCGTTPLHTAAMREALDTWA
AGRADVTTTHAEPNGTVARSPTRVLTAPELDLTPAAGPTRLREKLERGEFVVSVEIDPPK
GLNPTKALEGAFLLQEAGVDFINVADSPMARVRMSALTLCYLIQHRTGVETILHLTTRDR
SLMGLQSELLGAHAVGVRNIIALTGDPPSLGDYPDSSAVYDVDSIGLIRVLERLNNGADS
AGASIGRPAGFTIACAVDPTREDLAHEAGRLRAKLEAGAHVVMTQPIYDPSSWTSFLEAY
GVERLPVPVLAGILPLQSSKHAEFLHNEVPGITLSDEARERMRLAGPDGRREGVVMAQEL
LQALRPWVQGVYLMPSFGRYEVAAEVLKVLEREPAGA
>A0A6M8G7Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter citreus|TrEMBL
MGLLEKLSNGIVLGDGAMGTLLYSGGLHSCFEELNITERDRIIHIHEQYIDAGAEVIQTN
SYGANAGKLRQYGLEKLVKQINQMAVRNARAASKGRALVIGGIGGMKYVGSTFTTPLERE
MMLLEQASALLEEGVDGIMLETFYDENELYDAVNLLRGRTDLPIISQVTLQEIGIMQSGQ
YIEKILPRLVDLGADVVGINCHLGPLHMLESLNTVSLPTNGYLSAFPNSGLPLYAEGKYE
YKSNPEYFEDMAKPFIEQGVRLIGGCCGTTPAHIAALRKKIDTLKPVTKKEVKSRTIKIT
IPKQVEQKDETLPEKAKQKTTIIAELDPPKTLQTRKFFEGARALHSAGADAITLADNPLA
SPRISNVAMASLLQRLDVPVLTHLTCRDRNMIGLQSHLMGLSTLGLNEILAITGDPARVG
DFPGATSVYDVASLDLIRMIKEMNEGRLYSGKSLGNGTRFSVAAAFNPNIRKFDAAIKRL
EKKVEAGADYFLTQPIYDFETIDKLYEATRHIKQPIFIGVMPLVSKRNADFIHYEVPGIT
LSDEVRNRISSVEPEKAIDEGKKIAKELINYAKDKFNGIYLITPFLKYEITEDLIHFTKS
SNKEGIQL
>A0A0Q7NLV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Root483D2|TrEMBL
MPIHTLYPAERGNLRLSFEYFPPKNDDMESQLFQTAGDLSAFDPAFVTMTYGAGGSTKER
SLTAVRRMIDDEGFANTAAHLTCVGATKAEVDAVVAEFIGSGVRHFVVLRGDPQGGVGAR
YEPFADGYENAAALVAAIRAKGDFEISVSAYPEKHPESPDVAADIDMLKRKVDNGATRAL
TQFFFDNNDFERYLERVRRAGIQIPVVPGIMPINNLAGITKFAGLCGAKVPEAIVTRLVH
LDESPEERFKEATHIAAEQIVDLARRGLRDFHLYTMNRSPLVAAVCDLVGFERVPSAVVQ
PRSAGAAA
>A0A2A5S002|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus piscium|TrEMBL
MKITDIYKTKNKKNKSVISLEIFPPKTDAGVETIYHTVAELTNKPDFISVTYGAMGSFNQ
GNKTLRIAEKIKKDYNIETMHHLTSINNNPEQIAAILSDIKAKNVNNILALSGDMPVGAA
CSDFPDAYHFAYELINDIKKNGDFDIAAAIYPEGHVNSALEVENIEHVKRKYDAGANLFV
SQLFFDNEKFLRLNDYIKNSGIEAPIAAGIMPVLQKSQVERMIFFGASLPTRLIKIINKY
KDSPEDLQKAGMEYACKQIDDLLARGVDGVHIYTMNKPFVANTMMTKYL
>A0A4D9CCY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mastigocladus laminosus UU774|TrEMBL
MLIFMLDTQNPSCLTSFQTAAKAGKFLITAEVAPPKGGNPEQMLKMAATLKGRVHAVNIT
DGSRAVLRMSPVIASAILIQHGIEPICQIACRDRNRIGLQADLMGAHAIGIRNILALTGD
PVKAGDHPDCKGVFDLESVRLLQVIEKLNHGFDCNDKPLTDGALDLFPGAAVDPQCPSWS
GLQKRFERKLEAGAQFFQSQLITDFEILEKFMDQIAADCGKPILAGIFLLKSAKNAQFIN
RCVPGVNIPEHIIDRLAKAKDPLEEGMKIAAEQVQTAQQLCQGVHMMAVKREDLIPQILE
MAGVAPVNQMVLR
>A0A243RCZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium minutum|TrEMBL
MTDRPFELVCEVEPPTRPDLRHVRHQIGTLSKIAHSFLIPDNHIGRATVSSVAVAHEVQE
MGGRSIACINSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTSGNRTSDLTVRSMIEEV
RSLGEDPAFAQTPAFRVGTAAGLRPLPAWKRTADFMFVQVSFSIEALLRWREANPVDLPV
YAGVMVIASENHARRLADAIPDIDIPADLVERVASDRLAGVEAACEQVLRIRDSGAFDGV
HLIPVARYREVESRLSGIL
>A0A1F0MSG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC071B10|TrEMBL
MRGTLPSTRLSASAPLDSLGEAPVTPQRRARTALSFELIPPRHDADSGKIDELIAGLAAY
NPDYVAVTSSRRSDWLTGTAALIARVAETTNLRPIAHLACTAGTREELVTWIRTLIDAGV
RGFLALRGDLPETGMPAHYLQHATDLLNLIQDVEDEEAFRLAAGKLALSVACYPSGHAES
KNFDEDLDVLLAKQRLGADFAITQLFFNAQDYLDFVEVARLAGVRIPLIPGIMPMTSLKR
VQRMGELSGIAVPECVTRTLAQATTPEEEYELGMQMSAQLANTILDAGTGGLHVYTHNNL
AVTQDLLDRIGIVQPAGHSLI
>A0A1N7K5Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmobacter megaterium|TrEMBL
MTAPRISFEFFPPRSLEASFKLWETVQMLAPLQPGFVSVTYGAGGTTRKLTHEAVTAIGK
NFGLNVAAHLTCVDATRTETLEIAQQYAEAGVREIVALRGDAPKGADRFTPHPEGFADAV
ELIEALAATGKFTLRVGAYPEPHPDAADSTADVRWLKRKFQAGASSAITQFFFEADTFLR
FRDACVAEGITGPIIPGILPIENWEGTKRFAARCGTAVPAGLDERFAAAEAQGRADALSV
ELCVELCRKLMAEGVEDLHFYTLNRPYLSRDVCLALGVPAQPDLVKVA
>A0A2W2EL81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea aridisoli|TrEMBL
MTFELICEIEPPTKPDLKRVRHQIGTLTTIADAFLIPDNHIGRATVSSVAVAHEVEAMGG
RGIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTSGNRTSDLTVRSMIEEAREF
SPEFRLGAAAALRPVPAWKRTADFLFSQVSFSVEAQLRWREAHPVDMPVYAGVMVLASAN
HARGLAAAIPDIDIPGELVEKVAADRMAGVEAACEQVLALRDSGAFAGVHLVPVARYRDV
ESRLAGTL
>K0B0U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gottschalkia acidurici (strain ATCC 7906 / DSM 604 / BCRC 14475 / CIP 104303 / KCTC 5404 / NCIMB 10678 / 9a)|TrEMBL
MQDYIKNKIYHVEILPPKQDSKKLEADIELFAEKYNRVMKSGYCACIADNAMGHLAFQGT
EIIEELELNVNSEQVMIHLNTFHTKEDLHNILDTCKSKGIKDILVLSGDGSDQLPKLQPS
DIRVNGVVESVTSVELLKYIKDEYPDTFVLGAAFNPYQVKENEFSKLQRKINAGASFIVT
QPIIEKNAVVDELLEKYPDVPIIIEAWMSKNLQLLSEAVEYEIPQDIQFDPVETLKILHR
IYPENVVRLSLLGFKTQYHIIEDI
>A0A009KHK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 146457|TrEMBL
MSLFSQCLEQKQFCILVEYLCSNRDTLAVPLSLAGYPAMMTLADRVHSDEDSAPLELAQQ
YAPEIEKLLHFSGKGRDIQEFERFLNQAEQRGYHNLLLLSGDKLKNHNFGREIPAQRTRY
LESVSAVMAARQRHLFNIGVAFNPFKYTEAERDAQYLKLHKKIKAGADFLITQLGFDLDC
LQHSQSFISQHYKQFPLIACVMPLSLKRAQFMLKHQVAGLVIPAHIVHVLKSEYEADPVQ
AEANVYARCALQILICKHLGFVGVHLSACHKPQEQQKLEQFLKQYENWSLATCEKAWKQL
WKMDSGLELKPELATFSKPVPPAQIFKYKQMHLMHQLFFASHAALGVGRFIFKANFWNKA
RPDQLLLKMEHWSKHPLVGCESCGHCRLDDTLYICPETCPKGLANGPCGGTSLDRGEFGD
RECIHSVKARLAKHLGQTELLRSKLIPAISIETRYTSSWKNWFKHSESH
>A0A7J3NP77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MLKLMDVLGKGFTLIGQVDSARTVDMGAILNAVKSMGNVSAVIVSEPRGMLGVANTVVVS
GLVKKETGKEVICQLTCRDRNRAALLSDVLAAKMLGIDSFLVTDGGHPKISDTPQAMAVF
DLDSAQLVQMLRHLSEKGETLAGHSIVGKLNIYVGTMAFPVASPIEVEVKRLERMVGLGL
NFMVTYPTFNIEALNRFQSETKRLGVPVIVGVRMLQDVRDARRLNEDPRVTVPPELIDSL
EKAEKLRGEEKANARLEANISFFEGFIESIKGKGFAGCSIYAPGIEQAVSQLASRLQA
>A0A6H1Y2Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas piezotolerans|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAARHPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAKYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIREETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GTDVVTRLCERLLDGGAPGLHFYTLNQAAPVLKVVDNLR
>E0REU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus polymyxa (strain E681)|TrEMBL
MKADLRTVLNREIIVGDGAMGTFLYQLGFPVNTSFEELNITSPDVISDVHGQYLSAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
LELARNYEQQIDALLSEGVDGILCETFYSLDEIRIALHSVRKYSDIPVICQFAVDQVGRT
QDGFLVAEAFSVLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAKSFVDLGTRLLGGCCGTTPDHIAAISKALNRLQPPPLASKEALL
KESFQVAEQIADEGERGNGRHTSEPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHALK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYVMTQPVYDHELIAAIAEATRHLEVPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGPEGRAMGVSIAKELLDTAMEHFNGIYFMTP
FMFYEMTAELTSYVWQKSGRAQAPLFRL
>A0A537GW16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MGRDLRQARERCEGSGTCEGGFTVKLSERAKYHPIVTAEVIPDRVVPAHLPLLDGRVDAI
TIPALRNGERDPSYPSEFRVTPQTRSVASAVIVKKTGFEAVPSLTCRDFRRSDLSLLPGL
FKKGLENFLVVFGDPYPNYDLKRYDFKRTEDLIDGIRSVFEGPRPCIGAVTNQYALNREK
EITRALSKVDAGADYVVTNSAFDDYYVLDY
>M3ZAC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nomascus leucogenys|TrEMBL
MGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSL
CQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPI
FWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEEL
TSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQ
PNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKG
ENITNAPELQPNPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIERWGKLYEEES
PSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNERETEAP
>A0A3R7F9R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MTGEIISDLMKNLKSGKFTFTGELEPKKTTNLEHIFESVQRLKGYVTACNVTDNPQSFAC
ISSLAASYLIQKETGMETIYQVTCRDRNRIGLLSDLLGAGALGIKNILALTGDYTTLGDT
PQAKPVFDLDSVQLISMIRRIVDEGKDINGQPIESPPKFFVGAAANPNADPLEPELIKFA
KKVSAGAQFFQTQVVFDIETAKRFLGETERYGVPVLIGIFPLKSYGIAKYFDKTVPGVKV
PEELMEKLRAAKKISDKKEKRERYNSINLEYFSDFIKELKKTTSAAGCHVMSVGYEELIP
SLVEAAK
>A0A1I0CFZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassotalea agarivorans|TrEMBL
MSYSHARQVESLNRSLSEINGDLQISFEFFPPNSPEMETTLWNSIERLAPLKPSFVSVTY
GAGSGTRDRTHDVIKRIQKDTALIAAPHLTCIDASRDELKTIAKEYWDTGVRHIVALRGD
LPDSNEKPNMYASDLVSLLKDVADFDISVAAYPEGHPEAPNPQFDLLNLKRKVEAGANRA
ISQFFFDIESYLRFRDRCVNVGIDVEIVPGILPVTNYKTLARFAKLTNVNIPNWMPKMFD
GLEDDETTRRLVGANIAMEQVKVLNSEGVKNFHFYTLNRAELTYAICHMLGIRP
>S5SQ67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nasuia deltocephalinicola str. NAS-ALF|TrEMBL
MIKFSIEFYINIYKIKEILNFNISMLCLKPLFLTITYNKFNINKKVINYLIKKNLKILPH
IICKKKIKNFNYLLNSYFLINLKNLMIIKGDNSKNNYYYSYNIVNLIKKNYINEFNIFLG
DYTESHPSSLNFLINIKNNKIKNIIKKNVNFISQYFYNIESYYNFYDNLKKINYKIKFIP
GIMFIKDFYKIVSFSNICKTELPLWIIKKLNNNKFYKKEYKKTNKEIILNLILKLLNFKV
KILHFYSMNNSYLVNIICESLNNNLNL
>A0A2T2S1X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium QS_8_64_29|TrEMBL
MSDCFRRAIRAQEFLVTAEVSPPKGGNPDHMLAMARALQGRVHAVNITDGSRAVARMSSL
AAASLLQQQGIEPVCQLACRDRNRIGLQADLMGAHALGLRNVLALTGDPVSAGDNDDAQA
VFELESVRLLKLIGQLNSGYDPTDNALPDGGLALFPGAAVDPQLKSWSGLKRRFERKVKA
GAQFFQSQMLTDFDRLEQFMTQVAAGSEKPVLAGIFLFKSAKNARFIDRCVPGVTIPEEI
VQRLERATDPLDEGITIAAEQVQMARERCHGVHMMAVRKEHLIPQILDQAGVAPVDRAAP
AAAPAAASYSGLG
>A0A0Q8F0T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas sp. Root65|TrEMBL
MPSISFEFYPPKTDEQRAQLDRTADKLKAYRPEYVSCTFGAGGSTLSYTSETVRHLNQHH
RFDAAPHLSCVGGSREEIRELLRLYRALGCKRIVALRGDLPSGMGHPGDLRYASELIEFI
RAEQGDTFHIEVGAYPETHPQADDALTDLRHFKAKVDAGANGAITQYFYNPDAYFHFVDA
VRKLGVEIPIIPGIMPISNFSQLRRFSEACGAEIPRWIGKRMQALGDDAEAIRDFGADVV
ANLCERLVAGGAPSLHFYTLNLAKPTQSVLSRLGWSA
>A0A261QMP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sodalis-like symbiont of Philaenus spumarius|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEKTLWQSIDRLSELKPTFVSVTY
GANSGERERTHSIIKEIKERTGLDAAPHLTCIDATPPELQAIAQDYWRSGIRRIVALRGD
LPPGSGRPAMYGADLVVLLKKVGDFDISVAAYPEMHSEAKSAQSDLINLKRKVDAGASRA
ITQFFFDLESYLRFRDRCVAAGIDTEIVPGILPVSNFSQLQRFAAVTNVKVPNWMTTMFD
GLDHDLETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELTYAICHTLGVRPEIKIAP
AAHRDALSRVPMSRVSDVRA
>A0A1A9G183|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp. (strain HZN7)|TrEMBL
MKPATASPARKDIRLSFEFFPPKSAEAEGQLWETAAALSAYEPGFMSVTYGAGGSTKAPT
LATVRHLLAMGLPAASHLTCVGATKEEVHAVVAEFQAVGVRHFVALRGDPPGGVGTAYRP
HPGGYANAAELTAGLRSLADFEISVSAYPEKHPQSPDVAADIDMLKRKVDSGATRALTQF
FFENDDFERYLERVRKAGIAIPVVPGILPVHNLSQVQKFAGLCGASVPGWLADRLAPVDD
RPQERAAVAIDLAARQVEDLIARGIGEFHFYTMNRATLVSAVCDRVGFARNDRHTAGAAA
>A0A286GYC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. DSM 44270|TrEMBL
MEPESSAAGRLGCPKRMVFGPCGGVRDDGRCELAEHRCVFLDEPLVRWPGPAVEPPPPTG
LLERAQHGPVVLADLSVPPFDAAAVRRVVSVLGPQSDGLLLGEHANRPDFPPTMLAAEAL
AAGGRLWTTLACRDRNRVVLEQELAGLAALGVDGVLCVTGDGRGPGVRPGVSQVFDLDGV
RLAALAAGHGLQVAVPESPEAPPVDLRPARVAEKQRAGAQLCVLNHVRSPARVAAFVVAA
RAAGATLPFVAGVAVYTDERSARVLQHFPGLHLDDAVVEAVLAAPDPREAGIAAAVEEGR
ALLAVPGVVGVNLSGMGSGRGEDDGARIKAEVAERMREAA
>A0A7C1K8E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MFIKEFYASGQPVISFEIFPPKGADAMQVITDTVAGLQKLNPAFISVTYGAGGSTRERTI
EIAAAIKNRFQIEALAHLTCVGHTVAEINGILDRLQAEGIENVLALRGDPPAGVENFDYS
TCDFKYAVDLVRHIRGRSSVCIGAAAYPEGHISSPRLSTDLAYLKEKVDAGVDFLITQLF
FDNRVFYNFLENARRIGITCPIAAGILPVLNAGQIKRIVSLCGASIPAKLWLMVDRYADN
PEDLQKAGIEYASAQIGDLLANGVDGVHLYTLNKVEPAAQILENAGLI
>A0A7C2YPV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MEISNLAKKLNEGKFVITSEIGPGKGINLEFLKEAEILKDKVDAFNVTDLQSSVMRLGSL
ATCHLLVEMGLEPIFQITCRDRNRLALQSDLLSAYVLGIRNVLILTGDHPILGDHPEAKP
VFDLDSVSLLKVASDLMDGKDMKGNQLDGSPKFFLGAVVSPCYEPLELQIIKMEKKIEAG
AKFFQTQAIYDLKKFEEFMKRVEKYKVPILGGIVLLKSAGMAKYMNENVAGVSVPEKYIK
MLAEAKKEERVKVSLQIGAELIKGMKELCQGIHIMPLGWDKYVPELLSLSNLI
>A0A3C1YED2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MVSAFKEALSSGKFVVTSEIGPPKGTNLKNMNHHIELLKDKVDALNITDHQSSVMRAPSI
AGCLAVKECGGEPILQMTCRDRNRIALQADLLFAYSRGIRNVLCLTGDAVPVGDNKEAKG
VFDLDSVQLLQTIRTLESGMDLGGNGLDGKVEFCRGAIVTPEAQPLEPQLAKFEKKVEAG
AEFIQTQAIYDMENFAKFMVYARQFPVKMLAGIVLLSSARMAKYMTENVPGIFVPQDLID
ELAAAPKGGALEKGIEIAGRMIAFLKKEKLCDGVHIMAINKEEVVPDILAAAGLVGT
>A0A5C5EC96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus shcherbakoviae subsp. psychrophilus|TrEMBL
MKIESKFQKKKPVLSFEIFPPKRDKAIQNIDETLAILSELNPDFISVTFGAGGSHTNNQT
VELAKRIKHQYGIDPLVHLTCLNHSKFEICELLEELRAADIDSILALRGDANPAVEAKKD
FRYASDLVKFIRQYGDFSISGACYPECHTESKNKVEDIAHLKEKVDSGVQHLISQLFFDN
NAFYSFQEHIQIAGMHVPVEAGIMPVINKSQIERMVTLCGASLPEKFSRVMHKYEDNKEA
LFDAGMAYAINQIVDLLAHDVDGIHIYTMNNPIVAKRICDGIKNLI
>A0A1Q7MBF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium 13_1_40CM_3_65_11|TrEMBL
MPAEVASRAIRAGSHLERILASGEFAVTAEIAPPASVDASEIRRHASLYRGTVDACNVTD
GQRALVRISSMAAATIALQEGVEPIMQMVSRDRNRIGLQSDLLGAAALGIRNVLCLWGDP
PTAGNEKDAKGVYDLSTEEMISTFRALRDTGVLRGGEKVDQAPKVFIGAAADPFRGSKEE
SFGKLRGKVTAGADFVQTQGVFDVDAFEEWMRLVRKEWLHDKVFILAGVIPLKSAKMARF
MVEKLGVVVPKQIVDRMERAPNPRSEGVSIAVRTIKALKKIEGVRGVHVMPIGWEEIVPA
IVKDAGLLPRPELAA
>W4VAB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetivibrio thermocellus JCM 21531|TrEMBL
MLKNISKAIIKYSLLREVNYEFSKFVQKKKPVISFEIFPPKLDTPIESIFGTLEQFKELK
PDFISVTYGAGGSAKDRTIEIASKIKNEYGIESMAHLTCVGHSKEEIDALLKSIRESNLE
NILALRGDPPANQPDFDFSKNAFQYANELIAHIRKNNGFCIAAAAYVEGHVNSKRLKDDL
LYLKQKVDTGVDFLVTQLFFDNRIFYDFLDKTSSIGITCPITPGIMPIFKADQIKRITSL
CGASIPAKLVIMMDKYGDNDDDMRKAGIEYASEQIRDLIDNGADGVHLLTMNRPKSTREI
LINTGLLR
>A0A1I1EXR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zunongwangia mangrovi|TrEMBL
MKVTEHIEKAKGKTLFSFEIVPPQKGKNIQELYDNIDPLMEFNPPFIDVTTSREEHIYIK
RDDGLLERKITRMRPGTVGICAAIKQKYDVDTIPHVLCGGFTKEETEYVLVDCHYLGIEN
VMALRGDAMKHQRYFEPTKGGHIYANELVGQIRDLSKGKYLNEVIDSENHPDFCIGVAGY
PEKHLESPSLETDLKKLKAKVDAGADYVVTQMFFNNQAYFEFVEKAKAMGINVPIIPGIK
PIAVKKHLQLLPHVFSIDLPQTLIESVEACKNNKEVRQVGIEWAIEQTKELKAAGVPVLH
FYSMGKSSNIKQIAEAVF
>A0A1Y4D9P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. An277|TrEMBL
MNVIDSITNSTQTAFTFEILPPLKGNSIQKVYNVIDKLREFEPKYINITSHHSEYIYKPQ
PDGSLRKVNIRKRPGSVAIAAAIQNKYGIPAVPHIICKGFTKEETEYALIDLNFLGVHNL
LLLSGDIKTLEVEQQPELYHAHATDLQGQVNQFNMGVLLDGSPIEGIDTPFSYGMACYPE
KHEEAPNMESDLHYAKMKVMNGASYLVTQMFFDNTKYYDFVSRCRAEGIQVPIIPGIKPI
VFRNQLTVLPRVFRSDIPEPLEKELRKCKTDEEAKEVGVEWSIMQCKDLMAHEVPSLHFY
TMMASDSVRRIASAIY
>A0A1C5ZIK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Bacteroides sp|TrEMBL
MSVFFHKFVSIVNNTYKYKKKMSVIDLINAEKSTAFSFEILPPLKGTGIDRLLSDIETLL
PYNPKYINITTHRSEYVYMPEPNGMFCRKLTRRRPGTVAVAAAIKAKYGVTVVPHMLCSG
YTPEETEYTLIDLQFLGITDLLVLRGDKAPHQKSFTPENGGHAHAIDLQLQINKYNQGIF
FDGTEMDKLPPQFCYGVACYPEKHEESPNAERDLYWLQKKVEAGAQYAVTQMFFDNNKYF
DFVEKARNAGINVPIIPGIKPLKKLTQLNVLPRTFKIDLPEELAAEVRKCKSDQDVAALG
CEWTIKQCKELMEHGVPSIHFYSVGAVDSIAKIAKEIY
>A0A0R1YWE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus parafarraginis DSM 18390 = JCM 14109|TrEMBL
MSLTALFKDKTVFSLEVFPPKKDSPKEAILPTLQQLQAINPDFISVTLGAGGSTHSSGTV
QITDLIQNQLNIPAVAHVPGLYQTKEQVLNLLDHLAENNVKNILALRGDRIPGKEPAGVF
NHANELISFVHEKRPDFSIASACYPDCHAEAASFVDDIAHLRQKVDAGADHLISQLFFDN
QSFYDFKEKTEIAGIHVPIEAGIMPCTNKKQIERIASITGVPLPKKFVAILDRYADSKEA
MRDAGIAFAVDQIIDLVSEGVDGIHLYTMNRADIAERIWDATKSVFAAANSKKQQRASSH
>A4C983|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas tunicata D2|TrEMBL
MALSLQEKIEDANQGVYLIGTTPPKIDTDKAQLEMIAQKLLSRLHEIEYDGVVIYDIQDE
SSRISAPRPFPFKQTVDPREYSQLLSNLSELDVITYKSVAQRGVAEFKTWLNETKKEFNL
KNLVLVGSPSSEGDIKLSLPDAYQTLAQSEQDFFLGGVTIAERHASKRNEHSRLIEKTQQ
GCKFFISQAVYDAQATIDLITSYARTCRQEGIKPNRVILTFTPCGGEKTLQFMQWLGIAV
PEATKWRILDADDSLNESIRICRENLNQILRSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKATMELNLAEKQIA
>A0A2S2DZL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saliniradius amylolyticus|TrEMBL
MVSYARGIDALNQSLADIKNIDVSFEFFPPKTEQMEQTLWSSVERLAPLKPAYMSVTYGA
NSGERDRTHDVVKRIQNETGISAAPHLTCVDASREELVQIAKDYWDAGIRRIVALRGDLP
PGVTETELYGADLVALLKEVADFDISVAAYPEVHPEAPNSQFDLLNLKRKVDAGADQAIT
QFFFDAEVFLRFRDRAAAAGIEANLIPGILPVTNYKTLVKFAGMTNVNVPNWLHRMYEGL
DENDQTTRNLLGASISMDMVKILAKEGVRNFHFYTLNRSELSFAICHMLGLRAEQG
>A0A0P8YFY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxobacter pfennigii|TrEMBL
MDSDINKFKESLFDKSKMSVTWELVPGRGANEKTQEAVIENAKLAAKGQRIHALTLTDNP
GGVPAITPEGLASEVIKLGIEPLVHFTCKDKNRNELEGLLYSLDRTKVRNILVMTGDYVY
AGFLGRPKPVFDLEPMHVLMLLEEMNKGLEYKGIRGIIKHNPSDFFAGAVCSPFKQTEAE
TMVQYYKLKMKISSGAKYIVSQIGYDARKIHELLLFINSLNLNIPVIGNIYVLSHGTAKL
MNKNRIPGVIVTDKLLSEIENESYSPDKGAEAKLLRCAKLYAIMKGMGYAGVHIGGHGIR
YEDVEYIIDKGEELSGTWMDFLPQFDYPIRDGFYYFEKDEKTGLNRDAVSERRERPLDTK
VELVYPMSKIVHSLMLEPGTPLWKPMRAICKAIEDTPLEEPFHFVEHISKTVLYHCKDCG
DCALPDVAYVCPMSQCPKQIRNGICGGSYLGWCEVYPFKKKCEWVRAYARLKNSGKTREL
DHDVIPPCNYHLTQTSSWINLYLGRDHNAKKYGVEPVHKKIH
>A0A2N2MKW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-6|TrEMBL
MNKFLSLLESPSPLLADGAMGTLLHTHGVEHTHCFDELNLTDPARVADVHRQYIDAGAQI
ILTNTFGANRYKLHKHGLDDKTAQINRAAVALARRVVDASFKPVLIAGDVGPLGVRIAPY
GRVQPHEARAAFAEQILSFDGVDLIVIETMTDLYEALEAIAAAKEVAPQTPVVATMTFTR
DNRTLLGDDPAKVAIALRDAGADVVGVNCSGGPAQLIRILREMRQAVSAPGADTQAGPYL
WVKPNAGWPEHVGGRVMYAAAPEYFRDYALEFWKAGANVIGGCCGTTPEHIAAMRKTLDA
HPDIQVEAVQSVDSVSTSETAGAEPPSELAQKFAAGKFVYAVEMDPPRGLATQKLVAAAS
LLKEAGADVIDVADSPMARMRMSAWAVCDIIQRKIGIETTLHFPTRGRNLLRVQGDLLAS
HALGVRNVFVVMGDPTSIGDYPEAADNYDLVPSGLAKLIKQGFNAGVDHAGASIGQPTSF
YVGAALNLCSPEPETEIKNLKRKLKAGADFFLTQPIYDPEKAQGFLQRFAEQTGAPLDRP
VLVGILPLASVRHANFLQNEVPGIVIPEQTMQRMNQAGDGASREGVKIAVELIQHIKQWA
QGVYIMPQFHRYDLVAEIIEASTI
>A0A7K3QEL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces diastaticus|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPTADWVAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPDSYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILSVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A7X7PTW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium|TrEMBL
MSIEQLNDRIGNAVAKQRVRPTVSFEFFPPKDEAMEQTLWRSIDRLLPLQPRFVSVTYGA
DGSTRTRTHNIVTQIQESTALTAAPHLTCVGAPKDEVLDIARNYWAHGIRHIVALRGDPP
QGCGGKYVPHPRGFAYAVDLVKGLKSVGDFEISVATYPERHPEAPSEAFELENLKAKVDA
GADRAITQFFFDPDVFLRFRDRCAAAGITASIVPGILPITRFPQMLRMAQRCGASVPDWL
VQRFDGLDEDADTRRMIAAAVAIEQVQALQRHGVDEFHFYTLNRFELTYAICHALGVRPQ
SNDLQREAS
>A0A1F9I1X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFCSPLOWO2_02_FULL_47_10|TrEMBL
MQPFIEALNERVILADGAMGTLLYERGVFLNRCYDELNLTSPEIVKKIHLDYLAAGAELI
ETNTFTANRMRLAPYGLEGKVREINSAGVRLAREASEGRAYVAGSVGPLGVTLAPLGRHT
QGEAREIFREQIEAIVEAGADSLVFETFMNMDELEIAVKEAQRITNLPIVAQVSFKHYRE
GEFVGVTPASAIKIIEGWGVAVGGTNCSSGPQGVLDAVQEMRKVSQMKLIAMPNSGMPQM
VEGRMLYLATPEYMGEYARRLVQAGANIIGGCCGTTPAEIKEMARFIKAVTPKVQKNTPS
LSLPPRGGGAGRGGSVIKIIPTSQKSIFASRLGKKFAVSVELDPPMGLSAKEAIAHAKFL
HEHGVDAVNIADGPRAMARMSPIALATLVKKETGIEPIVHYCCRDRNLLGMQMDLLGAHA
LELKNLLIITGDPPKMGTYPMATAVFDIDSIGLIHMVNMMNHGRDLTGRELNDATSFLIG
CGVNPGAVNIELEVARYAKKIEAGAEYVFSQPVYDPELLERFFKLTAGVKEIPFFVGILP
LASLKNAEFLHNEVPGMQIPSHIMSRMQTAKTRDAQRFEGMAIAKEALAAAKKMPRVNGA
YVFPPFGKYEAVVELLDY
>A0A537KT67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrabacteria group bacterium ANGP1|TrEMBL
MVRPELKSHPFLARLDQGVLLADGAMGTLVYARGVSFDQCFDELNLSRPELVRQIHLDYI
ESGAELIETNTFGANRFKLGQHNLAHRVAEISHAGAALAREAALTANRQVFVAGSMGPIG
RPMVPLGAVTPEEVRSAYAEQAAALVEGGADVLILETFTDLNELLEAVRGVQEATTVPLI
AQMTFTQEGKTIVGHEPREIVRALEQTGVEVVGANCSVGSQGILDVLQQMAASVTRARLS
AMPNAGFPAYVSGRYIYFSTPAYMAGYATQLAAVGVRVIGGCCGTTPEHIAAMRHALAEP
VARAAGLTIPAELRSSRPAEPEPAARPQTPTPLAQKLGRTFVVSVEIDPPRGVHDRRELD
GCRRLKDAGVDVVDVADNPMARLRMSPWAMCARIQSEVSLETVLHFTTRDRNLMRLQSDL
LAVHALGVRNVLVLRGDPPQMGDYPNATAVSDVKPSGLVRLIKKFNQGHDVAGNAIGAPT
GFTVGVALNLAAPDLDREARILERKMAAGADFICTMPIYEPEALDRFERIMGGLPRPALI
GVLPLVSHRHAEFLHNELPGFAVPSWVRERMRLAADGRQEGMGVAHELMEAVRSRVGGVY
LIPSFGRYDGVLELVRLARQPAKT
>A0A2U2ZEL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NWU339|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFSAPKTPKGQRNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVHETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMADWIPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSAEWDTDVAHFVD
KCRAGADYAITQMFFHPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPQLSNASF
PDALKERILAAADDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPLRA
>A0A1M5MHP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWH9|TrEMBL
MKIVDILKQDKMSLSFEVFPPKKETSFESVKNATESIAALGPAFMSVTYGAGGGVSQYTL
EIAKNLKSKFGVPMLAHLTCVSSSKETVKQRIEDMKAAGITNVMALRGDLTPELIANGRT
DCDYHHAVELVRELKESGADFCIGAACYPEKHPESANQREDIKYLKEKVDAGADFLTTQM
IFDNNLFFNFLYKLREAGVTCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGIMRNVSAILGKNFIA
>I3CP12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. GW103|TrEMBL
MSTHNFSIEFFPPKTAEGTEKLRATRARLAALAPKYFSVTFGAGGSTQQGTRDTVLEIIG
EGHDAAPHLSCIGSSRASLRAILEDYRAHGIKRLVALRGDLPSGYGAMDQASSEFRHANE
LVEFVRAETGDWFHIEVAAYPEMHPQARSPQDDVQNFVRKVKAGANSAITQYFYNADAYF
RFVDEAAKLGATVPVIAGIMPITNYTQLMRFSDMCGTEIPRWIRLKLASYGDDTESIRAF
GQDVVIQLCQRLLAGGAPGLHFYSLNQAGPTEAIWQQLVK
>W7Q2C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. BC04|TrEMBL
MSTQAHPLGISFEFFPPNTDLGREKLMGVLDALASRSPRFFSVTYGAGGSTQARTLSTVQ
TVRESGITTAPHLSCIGSEKAQLRDLLHQYREQGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFEKDLENFVRKMKAGANLAITQYFFTADAYF
HFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSESIAAF
GEEVVSRLCQRLLDGGAPGLHFYTLNQATPSLRVLDNLS
>A0A258GAW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium 32-67-9|TrEMBL
MPAPRISFEFFPPQTLDASFRLWETVQMLAPLKPSFVSVTYGAGGTTRKLTHDAVTTIGA
NFGLNVAAHLTCVEATKAETLEIAQSYAEAGVTEIVALRGDAPKGAERFTAHDDGFASSV
ELIEALAATGKFTLRVGAYPEAHPDAADMAANVAWLKRKIDAGASSAITQFFFEAETFFR
FRDACAAAGIDAPIIPGILPVTSWAGTKRFAERCGTSVPQWLDDAFAAAVRDGREELLAT
ALATELCDDLLQGGVEDLHFYTLNRPHLTRDICFALGIVPEVSLQNVA
>A0A256YYY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon ex4484_40|TrEMBL
MSRPVFSELMAQIRAGKFVFTGELEPEKTIDLTETLEAARRLKGYVTACNVTDNPQAFAY
ISSLAASYIVQKETGVETIYQITCRDRNRIAIT
>A0A6I4RHQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. zg-70|TrEMBL
MVHTPSLSFEVFPPNPAAGNEKILSALQDMQGLAPHFISVTASNNTFNIEETTVRLTDYI
QNDLGIPSIAHLPAIYLTKKQVTTILAALDQIGVHKILALRGDILPDVTPQKDFQYATDL
ISFIKEEAPHFDIIGACYPEVHPDSPNQLSDIKHLKKKVDAGCSTLVTQLFFDNDVFYDF
QEKCHLADIDVPILAGIMPIINRNQALRLLNTCENIRLPRKFRAILDKYEHDPESLKAAG
LAYAIDQIVDLVTHDVAGIHLYTMNNPYVAKHIYRATYSLFKHSPLIAKA
>A0A7C1E2N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidicoccus fontis|TrEMBL
MKFYVEVQPSRFRDKLDEQFAVIKEVSERVHVPDAPMGYPKASSIVIAFLALAHGLRATV
HLRTTDYSYVGFLNQIYGAHLIGIDKMLLLRGDPPYRGSTVSDVSPEEGLRIIRSDERLS
AMKVGFILSLRYPIEKIRERICFNPDFVLVTHKSREKLSWLTDSYGGEKIGYLIVSTPRN
EELVKKLPQREDVCRLEKLAECVDESSVYLDSLLVSCPEDIKECVYALKKIM
>A0A0B1YID0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia sp. A12|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRSILGTYREHGIGRIVALRGDMPSGMGEIGEFRYANELVEF
IRQETGNAFHIEVAAYPEYHPQARSARQDLDNFARKVKAGADSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWVAKRLESFGDDRESIRAFGLDV
VTALCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A6N2BUW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solanum chilense|TrEMBL
MKVIEKIQEAAKTDKVIFSFEFFPPKTDDGVENLFERMERMVAHGPSFCDITWGAGGSTA
DLTLEIVNRMQNMVCVESMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGIATKEIYENDLAYLK
KKVDAGADVIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTK
IPDEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALAILMNL
GLIEESKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTTGWDEYPHGRWSNAQNP
SYGALTDYQFMRARSRDKKLQEEWAAALNSVEDVYEKFKDYCLGKLRSCPWSELDGLQPE
TKIINEKLGQVNTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSQEKLN
TLVEKCKSFPYLTYMAVNKEGNWISNVNQTDINAVTWGVFPAKEIIQPTVVDPASFMIWK
DEAFEIWSRGWAQLYPETDPSRKLLEQVQNSYFLVSLVDNDYINGDLFSIFKDI
>L9LQE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WC-743|TrEMBL
MAGFPACMTLSDRVRSDEDIAPLIAAQAYPDHIEKVLHYAGKGRDIDDFKLFLKQADSVG
LRDILLLTGDKLKQHHDGQGQHARTRYLESVNAVMAAHQYGGFHIGVAFNPFKYTPAEQQ
AQYLKLHKKLNAGADYIITQLGFDLSALKQLQTFLAQEKYIQKTLACVMPLTLARAQFMV
KHKVAGIVITPHMLEVLTQDQVNQCPENVYKRCALQILICQHLGYAGVHLSACHKADEQM
LLEQYIEQYRDLNLSQCEILWNQLWQLAEGEQLRPKVAAKRIKSALNNKVKYQFLDLIHR
AVFQSSFVKGVGTFIFNASFWNRKTAAKVLLQTEYLSKHYLLGCESCGQCRLAETLYICP
ETCPKGLANGPCGGTELDRCEFGDRECIHSVKSRLAHDVDQIQLLKEQLIPTVPIEVRGT
SSWKNWYKAE
>A0A1F8VBJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coxiella sp. RIFCSPHIGHO2_12_FULL_44_14|TrEMBL
MDEKLKLPISFEFFPPKTEHGLLSLVQCAEILSKWEPEYFSVTFGAGGSTQENTLKIVRS
LTQKKLTMAPHLTCVGLTKPQIRDLLNQYRAMGITRIVALRGDEVGENTSQSCFKFANEL
VEFIRLETGNHFFIEVAAYPEFHPQAKSVSSDLNAFKRKVAAGANRAITQYFYNVEAYFR
FQESCAAHQISIPVVPGIMPIRDVQQLIRFSKLCGADLPLWLIKRLASYEGDAVAVQQFG
IDVVTRLCERLIIGGAPGLHFYTLNNLEPTVSILRILGVERSITASLEYLETV
>A0A1J6I3S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella cytisi|TrEMBL
MGFYGLSRRPDIGQTTRVSFEFFPPKSEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDVKPAAHLTCVDATREEVDRVVREFAALGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFVTDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPSWLAERFE
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTEAAL
EVA
>A0A1H7Y7N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Frackibacter sp. WG12|TrEMBL
MSSNRRDDFLNQDDLLITVEVNPPKGIELEGKIKQLSKLSNRVAAVNVTDNPMANLAFNA
TIFAHHIQEELDLTAISHLTCRDKNLLGLQSDLLAANTLGVDNFLVLTGDDPKNGDHPDA
TGVFDLDSVGLVELITRLNEGFDAQGNSLTGRPKINPGVAVNPTADNLSVEIKRLNEKVE
AGAKFIQTQPVYDVDSLFRFLDYLGEIEIPILVGILPLKNEGMADYFNKNVPGIKISKEI
LARMRGAGLEEGIRICQELVTQIKDDVDGIHIMPVGGIETANQIIAA
>A0A1V4SC67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4484_190.3|TrEMBL
MPIDDKIQSGEFVVLGEFEPPKGADFSPLLTNANLVKGRVDAFVIPEMANAVMKASSLGG
CCFLQTHGFETVLQVSCRDRNRLALQADILAAAGIGISSVMVVPGEEIRYGDHHQARAVY
DVDLMELLDGIGRLQEGKDMAGIELQGAPRFFVGTTFNAGATGGAMGLELEELQKRVDKG
VQFVITTPVFDVAGFQQTLSRMEGLGAAIIPTVLLLKSAGMARYIDRNISHISIPSDMIQ
SIQKAPDKVRRCVQIAGELIAQLKQLGVAGVLVSTIGWEDKLPQVLDIARV
>X6E6J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNHC220B00|TrEMBL
MTGRQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDDITETQVDMVK
TAH
>A0A254SPX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWB2|TrEMBL
MKIIDILKQDKMSLSFEVFPPKKETSFENVKAATEAIAKLNPAFMSVTYGAGGGVSQYTL
EIAKNLKYNFNIPMLAHLTCISSTKETIHQRIEDMKAAGIKNVMALRGDLTPELIANGRG
DCDYHHAVELIRELKAADADFCIGAACYPEKHPESPNQAEDIKHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPDAMKQAGIIYATDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFAG
>A0A084DLQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. MSh2|TrEMBL
MASLLIHPENPGSAGNITDAYSLEVTAKDIPALTAAAPRLLPASTISIPYLPGEDNDARL
AAARAVRRLGFEPMPHFSARRIGSLAELDAFVTRAVAEAGVERCFVIAGDPSTPMGPFSD
SSSLIETGIFERSGIKVVGVGGHPDGHPVMSTADRWDVLERKCDSIARRGMTPLIVTQFA
FDADIVLTWLQALRERGIEHPVRVGVPGPAGIAVLARYAALCGVSACASMWSKYGVSIGK
LFGTAGPDRFVDRLATGLTPAHGKVSLHFFPFGGIAQSLKWIEQYRSRAEPPRA
>A0A5C5YS61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Posidoniimonas polymericola|TrEMBL
MTIAAAYGPDKLGLSFELFPPKTDKGEQTLLEHVERLMAFRPSYVTCTYGAGGSTQSKTL
EIVSRVRRDFGVAVATHLTCVGATADELRGYLGEAQAAGVQNVVALRGDPPQGAERFEQT
AGGFAYANELVAMIRSDFPDLGVAVAGYPEVHQEAPSREADLENLKRKVDAGADAVITQL
FYDNQDFFRFRDDCQRLGVDVPIVPGLLPITNTAQIKRITSLCGARLPADLVAKLEAAGD
DDQAQFEAGVEIATAQTVELIEQGVPGIHYYVLNKSEAASRVLQSVNLPG
>A0A1F1V3I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC08A12|TrEMBL
MASIRRQVAVSQSLSLYTPGRVPFSVEFMPPRDDAAEERLWNAAEAFHDLGVSFASVTYG
AGGSTRERTLRVAERLGTKPLTTLVHMTLVQHTKEELQDMLRTYASLGLTNLLALRGDPP
GDPNAEWVPTPGGLNYAVELIDMIREMPECADFDIGIASFPEGHYRTGSLEQDTEYTLAK
LRAGAQYSITQMFFDVDHYLRLRDRLAKADPEHGQKPIIPGLMPITSLRSVRRQMELAGA
ALPPKLEKRLLDAAAGDEVANRDAIREVGIEVTTEMAERLIAEGVPDLHFMTMNNVRATQ
EVLHNLGMAPAWGPGLGHDMVR
>L1QEU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium celatum DSM 1785|TrEMBL
MRLGAIYMKINELFESKKVVFSFEIFPPKATSSIDTIYSTLEELKDLKPDYISVTYGAGG
SLTKNKTTELSSIVKNKYGVESVAHLTCINSTKEEINIILDDLKFNGIENILALRGDVPE
GGNHKGDFKYAYELISHIKKRGDFNILGACYPEGHVKGRDLKEDMLHLKIKEESGASQFI
SQLFFDNNHFYNLLEEKEKLGIKSPIQAGIMPVVNKKQIERITSLCGVNMPKKFIKIMER
YEYDKEALRDAGIAYAVEQIVDLISSGVDGIHLYSMNNAYVARKINNSISSIINSINK
>A0A0Q4BHI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccales archaeon RumEn M1|TrEMBL
MTQHRSHLQRVLDSSEFAVTAEIGPPKSASGEAVRERARLLRGHADAFNLTDNQTAIVRL
SSVASAALCIQEGVEPVVQMTCRDRNRIGLQSDLLGAAALGVRNVLCLSGDHPRFGNQRE
AKSVYDIDPVQELMMFRKMRDEGKVWGGDALEQAPNVYLGAVANPFADPFELRVARLAKK
VDAGAEFIQTQAVFDLDRFERFMEQVRERRLDERAHILAGVVPLRSAGAARYMRDKVSGM
SVPDEVVERMKGAPEPRKEGVRICLETIERLRSIRGVHGVHIMAIGWEDIVPEIVERAGL
SPRPS
>A0A8J3UMB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planotetraspora silvatica|TrEMBL
MTNQPFQIICEIEPPTRPDLKHVRHQIGTLSKVADTFLVPDNHIGRATVSSVAVAHEVEA
MGGRSIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPSSGSRTGELNVRAMIEEV
RALPKDSAFTGVRPFRVGTAAALRPLPAWKRAADFMFVQVSFSLEALLRWREANPMDVPV
YAGVMVLASETHAQRLAAAIPDIDIPSELVEKVASDRLAGVEATCEQVLQIRDSGAFDGV
HLIPVARYREVAARLEHLLS
>A0A7Y3R6C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. IMCC34852|TrEMBL
MKVTQHIENANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEYKE
LPNGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKTETYFHPEKEGNAYATELVTQISNLNNGIYLDEDLKNSAKTNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNKKFFDFVDKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMAVVKAKDNDEVKQIGIDWCVAQSKELVAAGIPVLH
YYSMGKAENIKAIAKEVF
>A0A8C0NLR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Canis lupus familiaris|TrEMBL
MDQPPPGVLPATVRCSRLGLWTLEAGRVGFSVPPSISRSPAMVKEPRGDGDGGPTPRSEG
SSSGSESSKDSSRCSTPGLDPERHERLREKMRRRMESGDRWFSLEFFPPRTAEGAVNLIS
RFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQI
TGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYP
KGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFP
IQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGL
HFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRT
QEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARY
LSGEPNQHGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIV
GWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNA
VTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFL
VNLVDNEFPLDNCLWQVVEDTFELLKGPSPEREAEAV
>A0A7C2X937|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSDLHVSFEFFPPKSEAVQQRLWAAVEKLKPLAPDFMSVTYGAGGSTRERTHETVARIIK
DAGVPVAAHLTCVAATKAEVDQVLRDYWAEGVRHIVALRGDPPGGPGERYIPHPGGYANA
AELAAGARKIAGFEISVGCYPEKHPDSPSAAADIDMLKRKVDAGAARGITQFFYDNDVYY
RYVDRVRAAGIDIPIVPGIMAITNFASVRKMADTIGATIPGRLVKLFQNLDEDPQTRQLI
AATVAAEQCLALAEQGVKHFHFYTLNRDDLAYALCTMLGVRPTAQAKSAGAAA
>A0A7X3YEK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTLEVSFEFFPPQAAAGEGGLRRTLDALAPLGPRFVSVTCGAGGGGGESARGRTAAIATR
IARETKLPVAAHLTCAGASREEIDDAARAYWQAGIRHIVALRGDPPSGIGERYRPHPGGY
AYALDLVAGLRRLHEFEISVSAYPEGHPDAPGAAFEIDYLKRKIDAGATRAITQFFFETD
LYLRFRDRCRKAGIDCEIVAGILPIANFTQAARFARLCGAHLPSWLGAQFEGLEDDPETR
RMVAATVAVEQCRRLESEGVESLHFYTLNRPELTRAICHMVGVRPKLRQSAA
>A0A7Y9IRB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pigmentiphaga litoralis|TrEMBL
MISDVSSPNSAAQAEAPAAISLEFFPPRDNAAQERLVRTAKQLVAVGPSYVSVTFGAGGS
TREGTLNTVRTLQGLGYEVAPHLSCVGSTLDSLSETLASYRKAGIRRLVALRGDMPSGMG
DMGELRYASDLVRFIREESGDWFHIEVAAYPEMHPQAAGPDADLTHFVNKMNAGANGAIT
QYFFNADAYFDFLDRATAKGVLAPIVPGIMPITNHSQLARFSDMCGAEIPRWIRLRLASY
GDDKASIRAFGQDVMVELCQTLLDSGAPGLHFYTMNSPDATLGIWKQLEL
>A0A842PY59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrososphaera sp|TrEMBL
MYSDTINVSYELNPPKIVKGERFDLGQLKDNIQEMTNRASQLSGLVTGIHLTDSVLGVPR
LSSVTAARYIKEYIDAETRLSCSIRVRDRNFPSLCQTVSDAILIGAESVLILMGDEPADK
LGDSGLRPSSAVRMLKKEGYDLNIKLDLSFPAKVKDKSAQSIRNKLNVTPHSLVSQSISS
LSDLGEIVDLAKPYGIKVTAVVMVPSEKNHQSASLIGLDWSEYESNPVDFIRQAAKMADA
VLLTSPNSFASGLQLLLQLKQ
>A0A849ULT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiritimatiellaceae bacterium|TrEMBL
MTVTQKLKTTGYPLISVEFFPPKTEAAQTAFHKGAVELTGLKPDFVSVTCGAGGSAAGPT
LEISKQLCGLGYDAVMPHCTCVGMSRSELASSTEALVEQGFQNVMALRGDPPRGEKFFKP
ADGGFRYAAELVGFLRDRHPQLCIGVAGYPEKHPEASSLETDIRRLKEKVDAGADFITTQ
LFLHNHVYFEFVEACRAVGITVPIIPGLLPVISLEQITRMRTFCEFHVPDEFLRNLEAAK
NDPLKMERIGLYWAIEQISELVEGGAPGIHLYLLNRARTALYPELFACLSRVRGG
>A0A2A4TKX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MRPSLFAAQAKDIDVSFEFFPPKSEKMEAALWTSIRKLEPLQPEMVSVTYGAGGSTRERT
HATISRILKETSLVPAAHLTCVAATRGEIDDIAREYWDMGVRHIVALRGDMPEAGATYAP
HGQGYVNAADLVDGLKKIGDFNISVAAYPESHPDSGSWQADIDNLKRKIDAGANQAITQY
FFDVDMYFRFMDRVLAAGITVPIIPGIMPVTNFAQARNFSAMCGTSMPKWLEDLFDGLDD
RPEIRRHVAATVAAEQCMRLYRGGVKKFHFYTLNRSELTTTICHFLGIRPPAGVKE
>A0A537Q0J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTEVASPSPDGHRAPKTPAISFEFFPPKTEEMERNLWDTINRLAPLAPNFVSVTYGAGGS
TRERTHSTIARILTETSLTPAAHLTCVDAPRADVDDVVARYHEVGVRHIVALRGDPAGGI
GSAYAPHAEGYRSSADLVASIKQAHSDIEVTVSAYPERHPESASFDADIDMLKAKVDAGA
GRAITQFFFDNDLYFRYLDRVRARGIEIPIVPGILPVQNFKQAANFAKRAGASMPDWLAQ
KFEGLDDDAETRKLVAAAVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPKSA
QKAA
>A0A523FZ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MVSPPPPANKRIRPMARQAKSGQDRPQVSFEFFPPRTEKMEETLWTAIRRLAPLAPRFVS
VTYGAGGSTRERTHATVVRILKETDLTPAAHLTCVGASRVEVLEVAREYWDAGIRHIVAL
RGDAPEGESPYRPHAEGFAYASDLVAGLMSVGDFEISVAAYPETHPEAAGPEADLDNLKR
KIDAGASRAITQFFFDVDHYFRFLDRARAGGITVPIVPGILPVTNFKQVRKFSALCGTEV
PDWLADLFQGLDDDAETRQLVAASVVADQCRLLAAGGVDEFHFYTLNRADLTYAISHILG
LRPNRPPSPAPGAGAG
>A0A1Q6GR62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides oleiciplenus|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAGAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESAFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKITKTPFSYGVACYP
EKHEEAPNIDTDIYWLKQKMEAGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELACEAMKCKTDEEARQVGIEWCVQQCKELMEHGVPSIHF
YSIGAVDSIKEVAKQVY
>A0A2E5DWJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTKPTISFEFFPAKTSDGHKSLLKTGEILSELTPLYLTVTYGAGGSTREGTVKTILDMRK
KTSAPIAAHLTFINTPIDDLKSYADDLWNQGIHHIIALRGDMPSDLQWPLDPDKDYFQFT
SNFVEAIKSWHDFEVTVGAYPEKHPDSPSLALDMIALQKKCEAGADRAISQFFFDNQVFL
TFAEVCKHMQIAAPIVPGLLPIHDFQSMCAFAEKCHTTVPPWLRERFENCSNPKQTAIDT
LYEQAKNLIDHGVPHLHFYTLNKADIVYDVCKKLGY
>A0A537Q426|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MRRPEFSEQPVTVPDHAPSGHLAALLASASVEVSSRGHQLQELRDHFARGTDVTITFLPG
DNYRHNIETAAALRLAGFNPVPHIAAREIASREALDDFLARSRGEAGVTRVLLVAGDVVA
AKGPFKSSHDVCASGLIEAHGFASISVAGHPEGHPYLSATATFKALEAWQDWGRQSNIRV
DVLTQFCFESAPILKWLGELDARGIGLPVIVGLAGPATVATLMKFALRCGIGNSMRALRG
QIGRYGRLLTDAGPDDVVRGLQSAPRAATAAISGFHLFPFGGLRKAASWLHTYRDEMAQP
TAAASCGGSQNP
>A0A537UD20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTARQPASRLEALLRARQFAITAEITPPVSCEADDLLRKALPLAGLADAVNLTDGAGARA
HLSAPIAACLLARAGIEPVLQFTCRDRNRLALEADLMGAAACSVRNVLCLTGDDPRAGDQ
PQTKPVFDVDSVALTAIARELRDKGELPSGRKVAGHAVFFLGAADVPIDPPPSWRPDKLA
AKAAAGAEFAQTQFCMDTGVVRRYSAQLAKHAGTRDLFLLIGVAPLRSARSARWMRERLY
GTIIPEAFIERLERATDAAAEGERIAVELIEELAAIPGVAGVHLMAPANEDALPRVIAEA
RKRLPSRQH
>A0A357YNJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium|TrEMBL
MKIPELIEKGGKTAFSFELLPPLKGNSIKQVFKTIDRLIEFDPKYINITTHHSENIYKED
DKGVYRKVNVRKRPGSVAIAAAIKNKYGIRAIPHIISQGFTKEETEYALIDLSFLGVTDL
LLLRGDTKKLDAEQRAMDSHLNATGLQDQVNNFNKGISFDGSRFAPPEVPFSYGMACYPE
KHEESPNMESEIFYTKMKVDNGADYLATQMFFDNRKYFEFVDKCRASGINVPIIPGIKPI
HLMSQLTVLPRIFRTDIPEELEKELRKCKSDNDAKEVGVEWCIKQCKELVEAKVPSIHFY
SLMATESVYRVAKEIY
>A0A379X439|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKRGGRFRYFSSGLSGGTSGSEKRAGRSA
>A0A2A5CM35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MPPSLFAEPAKDMAVSFEFFPPKTDKMEETLWQSIDRLAPLNPDMVSVTYGAGGSTRERT
HATISRILKETDLVPAAHLTCVAATRGEIDDIAREYWDMGVRHIVALRGDMPTIGAPYAP
DPDGYINAADLVAGLKKIGDFHLSVAAYPESHPDSVNVEADIDNLKRKIDAGADQAITQY
FFDVDMYLRFMDRVLAAGITVPVIPGIMPVTNFAQAKNFSARCGTSIPKWLEKLFEGLDD
RPEIRRHVAATVAAEQCMRLYRGGVKKFHFYTLNRSELTATICHFLGLRPTGDVS
>A0A0F2LW04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporothrix schenckii 1099-18|TrEMBL
MDKITDKIAALSPESYYFSLEFFPPKTSMGFANLRGRLDRMARALRPLFVNVTWGAGGST
AQKSLELAEICQRELGLTTCLHLTCTNMSRELIDKALEDAKALGIRNILALRGDPPRPTE
YSDETDKDAAAAGIAPGPSGELEFSWAVDLVRYIRKQHGDYFCIGVAAYPEGHAEESHPL
GQSLEHDLPYLVEKVQAGADFVMTQLFFDHAAYAHFESVLLAHPSGAFKDIPLIPGLMPI
QNYQMIKRTTKLSHARIPDELMARLDAVKKDDEKVKSVGVDIISELVEQVKEIKDRTRAD
RPKGFHFYTLNLEKAVSFILERTHLIPPGTPDEDEEAIAGEVAVVDDVATSGSLGVPSIR
INGSTGTGTGGAVHPPLDGHPARRQSSIGSDPRNRVIVSGRAASHPDYEATALEASVPAE
PVNTRSNTLAISEGEGVLGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMTVNQALKL
WGRPTTTEDINTIFIRYLGGELAAIPWSEEEFNAETATIRDQLVQLNAKGWWTVASQPAV
NGIPSTDATFGWGPTHGFVFQKAFVEFFLPSADWTALCTRLTDPEVRDKVCFYAINAAGD
FVSSDASGRVTDSRSGAEAAEEASTNAVTWGVFPGKEIVTPTIVEEVSFRAWSEEAFGIW
KEWAALYPKGSPTDILLEKTRNDYWLVNIIHHNYIEKDALWNLVSA
>A0A7J5B848|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gulosibacter chungangensis|TrEMBL
MIATQNPVVLLRDYSIEMTARDIDEVPEAASHLPAKTRVNVTFLATESLEQRVAGAKAVL
DAGLTPVPHIAARRLKGQSELRKSLRVLQDAGASKQLFVVGGDPAVPEGPYASSFEVIES
GILPEYGVEHVGIGGYPEGHPDISQDVLWEELEKKTRALAAQGLEANILTQFGFDEAPIL
DWIAEVRKRGITAKIRIGVPGPAGVKRLLGFARRFGISSSAGIVKKYGFSLTNLMGTAGP
DRLLETLAEHLDPEVHGDVGIHFYTFGGVAATSKWAEDYLAN
>K0FU82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis MC28|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTNRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQVALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A731TIR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. VII serovar 40:z4,z24:[z39]|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTREMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHGVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPSGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQARKFADMTNVRIPSWMSQMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6N6TC01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Contendobacter sp|TrEMBL
MDSQTRYPKIFSCEFFPPTTDEGMRKLFAAREALMRMRPAFFSVTYGAGGSTRDRTFQTI
QAIQAHSGVDAAPHLTCVASTRTGVREILDYYRAQGIHRLVALRGDLPSGMREFGEFRYA
NELVEFIRAETGDHFHIEVAAYPEFHPQAPNTERDLLNFKRKVEAGADSAITQYFYNPDS
YFRFVDDCEKLEIDLPIVPGIMPITNYTQLARFSDNCGAEIPRWIRKRLESFGDDRDAIR
AYGRDVVADLCRRLLAGGAPGLHFYTMNQASPTLAICERLGLLTTA
>A0A6I4MQF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. BA2|TrEMBL
MPTFSFEFFPPKTPKGERTLWEAIRRVEPLAPDFVSVTYGAGGSSRDRTVELTKRVAAET
TMSPVAHLTAVGHSVAELRRIVGQYADAGVRDVLVVRGDPPGDPNGPWIPHPDGLTYAHE
LVSLVRELGDFTVGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFRVEDYLRL
RERVVAAGCDTPIIPEIMPATDVRQISRFAELSGAAFPEDLAHRLEAARDNPADGHRIGV
EYATVMAERLLAEGAPGLHYITLNRSTAALEIHRNVLNSRSGPYVLADHR
>A0A534JVI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MTSPRHPLLARLDGGPLLCDGAMGTLLYERGVPYDRCFDALNLTDRERVLNVHLDYLRAG
AEMIETNTFGANAVKLDAHDLGGRVRDVNWHGAKIAKEARDIIGRAIWVAGSVGPLGKPV
APFGRISAAEARDVFRAQIDALVEGGVDALVLETFTDLDELLEAVRAARAACDLPVIAQM
SFTDDGRTRYGHGPAEVVAGLEQAGVDVIGANCSVGPVPMLEVIQRMASLTRRPLSAQPN
AGFPALVDGRYLYLSSPTHLAAYARKMVEAGAVVIGGCCGTTPAHISAIGQAIADLRPAP
FRAVVPEAPGRAEPIAPPVDQPTQLAEKLGRTFVISVEVDPPKGLDATKDLDGARLLKEA
GADVIDVGDSPIGRIRMGALAMCYLIQQQVGIETIIHFTTRDRNLMGVQADLIGAHALGV
RNILALTGEPPRGDYPNVTAVFDVDSVGLVRIIRRFNEGQDLAGRSIGRPARFLIGCALD
MNPETLDREVPRLERKLEAGADFFMTQPVYEPETLDGFERRVGKLPVPVLLGILPLQSFR
HAEFLHNEVPGITIPKWVRDRMQAAGGAGREEGLRLGRELLGALLGRIDGAYFMPSFGRY
ELVATLVREVRTRVAGHAARTRG
>A0A516Q647|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microlunatus elymi|TrEMBL
MRAPSIADLLARADRPLFSFELFPPRNEEEERRAWFTVRRLESLAPDFVSVTYGANGTTR
DRTIKITEQIAATTTLRTMAHLTAASQSKAQLRKVIGSYAAAGIRHVLAIRGDMPGGPTV
PWERHPDGLANATELVAMIRELGDFCIGVGAFPDIHPQERDADLDARVLAAKAAAGADFA
ITQLFFTPARYFELVDRVRSLGCDIPIIPGIQPVTRISQIQRFAELSGAELPASVVGRLE
AEGDEPKAVRKVGVEIAGELAAELLAGGAPGVHLYTMNRSLATREVYARLRREFGRA
>A0A4S2VFR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. A0592|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMAEWVAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSADWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVEKAGCDTPIIPEVMPVVGIKQLDRLPQLSTAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A091G7Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cuculus canorus|TrEMBL
MVNETQHTCSTSSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVEGFNYAVDL
VKHIRNEFDDYLDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNSPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A166E646|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sistotremastrum suecicum HHB10207 ss-3|TrEMBL
MKLVDKISLFTPANPFFTFEFFPPRTDQGFQKLIARITRLSRLNPLAVSVTWGAGGATIN
RSLDLAWATQREQRLETILHLTCTNMVQGLIDDVLKNAKECGIQNILALRGDPPRGEEYW
KPTDARFQHAADLVSYIRSSPLYSDYFCIGVAAYPEGHSDKLLEEDEELAYLKQKVDAGA
DYIMTQHFYDVDAFLEWVKKVRQKGIRVPIIPGIMPIQTYSSFLRLTKLCGTEAPPHVMD
ALEPIKHDDQRVKDFGVALAVEMIRKINASSEISGFHFCTLNLERSIVLILEQLGWTGEH
ASTTNRLITGASQVEVEDSSLNSNFRITPSEALDTAASTLAGKSSRGLAQEVGKGELNSE
ATWDEFPNGRFGDAKSPAFGIGQDPWNPSSSVLTGPDREWGSPKSTEDLTHLFLQYLHSE
ISSTPFSSNPLSLETKKILPQLVALNGAARWTVGSQPAVDSALSTDEVVGWGPPGGYVFQ
KSFVEFFTTHDDLLEIVSKLEKIDGDWFTFYAADSEDNFTSNVDAQARNAVTWGIFPGHE
VTQSTIIDKESFISWKEEAFEIWHQWALTYPPDCPERRILDEVWRTRWLVTIIHHDFKTP
DGLWKLLLDNRDSNETEDPNRVTK
>A0A512AC01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus cristatus|TrEMBL
MVNRQTPSLSFEVFPPSPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLAE
FISNDLEIPTIAHLPAVYLTKEMVSNILQALDRVGVNQILALRGDIFPDVAPKDDFKYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRT
AGLAYAVDQIVDLVTHDVAGIHLYTMNNAATAYHIYKATHALFNHTPSVQSF
>A0A093XTQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-3557|TrEMBL
MADSATTDKITDKIAALPQDASYFSLEFFPPKTAMGSTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSRALVDDALKAAKEAGIQNILALRGD
EPRGEYKDALEAGKEGEDEFVWAIDLVKYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
EHDLPYLVDKVKAGADFIMTQLFYDVDAYDKFEQILRDHSSGAFKTLPIIPGLMPIQSYQ
ILRRTTKLSNAKLPQSIIDRLDAVRTDDEMVKKVGVDIVAEIVESVRHTKSRTKGPKGFH
FYTLNLEKAVAFILERANLIPSFTPVLTSDVFVDDITDTIPLPQLLINGERKSRRQSSVG
SGPHNFVIIDREEASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNGR
WGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRTDISSIFVQYLNGTLSALPWSDEP
ITAESGLIKDELVKLNQKGWWTIASQPAVNAARSQDEVVGWGPKGGWVFQKAFVELFVPT
SDWARLKTLLEGNAEVSFLAQSASGEFLKSKLDLGPGEEGSETNAVTWGVFPGKEIVSPT
IVEEVSFRAWAEEAWQMWREWAAVFGKGGDESRRFLDGVAKDGWLVNVIWHDFVGMCKAK
EGRSEEEGYKGLWDVLIEA
>A0A3R9SKW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus cristatus|TrEMBL
MVNRQTSSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLAE
FISNDLEIPTIAHLPAVYLTKEMVSNILQALDRVGVNQILALRGDVFPDVAPKDDFKYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRT
AGLAYAVDQIVDLVTHDVAGIHLYTMNNAATAYHIYKATHALFNHTPSVQSF
>A0A424Y8J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tindallia sp. MSAO_Bac2|TrEMBL
MLKEKIIDKKSGILLYGLTPPKNNHTEEKLVEISTRQKERIKKMDIDGLILYDIQDEQER
CDEERPFPYMKTVDPEVYSNQYLSELEIPRIVYKCVGKHSKDSLEKWIKNPEDETRISVF
VGAATGTQQVSISLEKAYELAKNKSENFLLGGVAIPERHQKKNNEHERVMKKKGHGCRFF
VSQAVYHVEASKSFLSDYFYLCQEREISMVPMIFTLTPCGSIKTLKFMKWLGVSVPKWME
NELVHSSDTLAQSIKLSKNVFEELLEFAAKKNIPIGCNVESVSVKKEEIDASLELMNDIK
ILMK
>G7E669|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970)|TrEMBL
MKITDKLSSWPPDKPFYTFEYFPPKTDSGMSNLQFRLDRMASLRPAWVHITWGAGGSTQE
RSLQLAEYAQSMGLDVCLHLTCTNMKKSTLDDTLLRASRVGIANILALRGDPPRGEEYSI
PDQASDFRHAIDLVRYIRREYPDQFCIGVAGYPEGHSDSEGKQDDVAILKMKQEAGAHFI
VTQLFYDVDIFLQWHDTCRSQGITMPILPGIMPIQNYQSFRRMTNLCKTSLPTSLLKHLE
PIRNDDAAVKEYGVNLSVDIIQKLYEAGIRGFHLCTLNLEKSPRQILARLGWISDEERTQ
DEHLPLGPAIPASGAAPPGPATLRVAALRGDANASRTSTPTSWDEFPNGRFGDARSPAYG
DLDGWGVSLKLPPAEALRHWGYPEREEDISTIFARYIRGTLPAIPWSEEPLMSETASIIE
QLIQLNTTKHWWTVGSQPCVDGIPSQDQTYGFGPKGGYIYQKAFVEFFARESDVDSIANR
IAALGTKKMTYYASNRQGDLRTNMAPGDANAVTWGVFAGKEIVTPTLIEEESFKAWKTEA
FDIWSEWQHLYPFKSNSRSFLEQLTEQRWLVSIVHHDYKDTNGLWSFLLDADDHVTNAKG
TV
>A0A0G4ED86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vitrella brassicaformis (strain CCMP3155)|TrEMBL
MKITDAMCEFEKANEDKAFFSFEFFPPKTEAGVANLYDRFDRMAQLNPLWIDVTWGAGGS
TAQRTLELCTNALKYHGLEPLMHLTCTNMQKEMLDSALKECVEHGITNILALRGDPPKDQ
ERWTAVEGGLEHASDLVAYIRKNYGDFFCIAVAAYPEGHLENPDKEKDLQMLKVKQDAGA
DFAITQLFYDNEEYFAFLEKAKAIGVTIPILPGIMPIQSYQGFKKMTTFCKTKVPQHIID
DLEPIKDDDQAVKDYGVKLAVEMCREILDHGVKGLHFYTLNLETSVMRIIEGMMLVDTHI
SNRVLPWRPSVHKKRSREDVRPIFWANRPRSYMQRTAAWDEFPNGRWGNRDSPAFDFADH
YISSNVDPNETSMTHRREMWGEAPSSVADIAKVFCDYLSPATKVTRLPWCSDIIGDETSI
IRKQLIPLNRNGCLTVNSQPRVNAAISSDPYFGWGPKNGFVFQKAYCEFFCSPETLERIL
MGIEGEKCLSYAAINIDGDIRTNMPEGSVNAVTWGVFPCEEVKQPTVVDLVSFMAWKDEA
FSLWKEEWGAIYPEGSPSRQLITTIHDSWYLVNIVDNNFVCGDLFGILVGITGRAKMGSP
KANGSPKANGTINGTDNDVTTDGLV
>A0A5D4TUZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rossellomorea aquimaris|TrEMBL
MKPLLEALKERILIADGAIGTLLYSYGVDRCFEELNLSHPNEVLKVHKEYIDAGADIIQT
NTYGANYQKLSRYGLEDSVKEINTAAVRLARKAAGENTYILGTIGGIRGIKQNVSLEEIK
RSFREQLYCLLLEGVDGILLETYYDFEELTTVLNITKREADIPVIAQVSLHETGVLQNGM
EIKDALQQLELLGADVVGINCRMGPFHMVNSLEEVPLPKRAFLSVYPNASLPNYEEGRFY
YSAEPDYFGDISNELRLQGARIIGGCCGTTPDHIRSVASRLKSREPVKEKVVKAKKVVQL
SSPSIEGSLLHEQVRKKKTIIVELDPPKHLDTKLFFQGAEALKEAGIDALTLADNPLASP
RISNDAIGSLVSSKFDLTPLVHITCRDRNLIGLQSHLMGLHTLGIHNILAITGDPAKIGD
FPGAASVYDLSSLELIELIKQNNEGISFSGKSLRERTQFSVGAAFNPNFRHLDASVKRLE
KKKKAGADYFISQPIFGKDQLIQVHEATKHLDVPIFIGIMPLISSRNAEFLHHEVPGINV
PEETRQRMKEAGRDPVVARAVGMEIAKGLLDTAIDLFNGIYLITPFVRYDMSIELIHHIQ
EKTITEREVPYGHHFV
>A0A6M1RJF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grimontia sedimenti|TrEMBL
MNFEQGNVDCMPQLPDPAFAAAELIYHASLEATPRQVSALESRPEWLPEGIRVYVPFLPS
SNFEDAFDTCKTLLIWGAVPVPHLPARAVPSEEKLREWLLALKVIGVKQLLLISGDIETI
QGPYSDTMQLLQSGLLQEYGIEGIGVAGHPEGHPHADQATLKRALEFKRNYAKTHGLSLW
VVTQFSFDQTVLEQWLDEHQTILAGIPVYLGLAGPTRLKNLLSYAAQCGVATSAKALTKN
LSAVRLLRPWTPDSLLEGLAAYQSKRSESVLKGIHLFPFGGLKQSAEWLANKAR
>A0A2A8SES6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS018417|TrEMBL
MKLLDLLQRGIVIGDGAMGTLLHSHGLQSCFEELNLSEPERIISIHKQYVAAGADVIQTN
TYGANEGKLRMYGLEDRVRKINRAAVRHAKAAVTEKNAIVGTIGGMKHIGAVTTTDMERE
FMLLEQANALLEENVDGLLLETFYDEFELLHAVKVLRKQTNVPLIAQLALHEAGTTQNGN
SVDGVLKRLIEYGANVVGLNCQLGPLHMIESFKTIAIPEYGYLSAYPNAGLPKYVEGRYV
YEGSPAYFEEMAPEFIKQGVRLLGGCCGTTPAHIEAMKRALKNERPVTAKEVVKRAEVIA
TKRVNTVNRITLAEKAKKETTVIVELDPPKTLDTQRFFEGAKALKRAGTDAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLAALGMEEVLALTGDPARVG
DFPGATSVYDLSSVELIKMIKEMNNGRSILGKSIGAATHFSVGGAFNPNVRHIEAAVKRM
EKKIVAGAEYFLTQPIYDAAVIRNVYEATKHIEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRRRMDGHRTSEEAVAEGILISQELIDVAMELFNGIYLITPFLKYEVTEALVRYIQ
AKKEQKEGINV
>A0A7K3LWK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia desulfuricans|TrEMBL
MTTTSAASSVVERLSAPPVNGPVHFSVEFFPPRDAEAEARLWRAVRVFERLDPAFVSLTY
GAGGSTRDRTVRIAGEMATETTLVTVAHLTAVDHSIAELRSLVGAYADKGITNLLALRGD
PPGDPLGEWVAHPQGVRYAQELVELIDGLGDFHVGVASFPEGHHRARDLDEDTAVLVNKL
RAGAEYSVTQMFFDVEDYLRLRDRVVAADPEQGAKPIIPGIMPITSLASVRRMAELSGSV
IPPAVEARFAAAAGNGPEEDRAAVRATGIDFATETAERLISEGVPCLHFCSLNFTKATCE
VLGRVGVDVRAAMVAPAVG
>A0A6A6JY34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Westerdykella ornata|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTPMGFANLQVRLERMSQALRPLFVTVTWGAGGST
ANKSLELAEICQRQLGLTTCLHLTCTNMKRSIVDEALEQAKVLGIRNILALRGDAPRSEE
YRDETLPVEEDSNRDFQYAVDLVRYIKKQYGDYFCIGVAAYPEGHADESHPEHQDPKLDL
PYLVEKTKAGADFILTQLFFDVEAFDRFEAMLREDESGVFKKIPIIPGLMPIQSYQILRR
TTKLSHASLPRRLLERLDAVKGDDELVKKVGVQILSEIVEHIKQRPSVGKRGFHFYTLNL
EKAVSHILEDCRLIPLAYADEEALELSNGHDLLPPDGALTHIRRRLSSLDSSPHNRAILS
HPHSSHSGFQASESEVGFPQGPINSRANALAISEGEGTLGREATWDDFPNGRWGDARSPA
FGEIDGYGPTLHVSTPQALKFWGHPVEEDDISTIFRRHIQGELEAIPWSEQGLSPETSTI
TKELLELNAKGWWTVASQPAVDGVKSTDPVFGWGPKNGRVFQKPFVEFFLPSADWAKLKP
KLDAHDQVTYFAGNEAGDFESSDEASVNPVTWGTFAGKEILTPTIIEAVSFRSWLEEAFG
IWREWQRVYPSRTQSHKLLGDVCRDSWLVNVIWSDYRNGEGLWALLREVETQV
>A0A0M2VNI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. DMB20|TrEMBL
MKPDLRQAWENRVLIGDGAMGTFLYQKGFPVGISYEELNLTSPEVIGDVHRQYMESGAQV
LESNTFSANYDKLSKYGLESKVEEINRAGVRIAREAAGNNGYVVGAIGSIRGGKRNNISS
AELKSHFAQQIHALLTEGVDGILLETFYDVEEMLLALSQVRQVSDVPVISQFAVEDIART
LDGYTMKDALRIVRQEGADVFGFNCRTGPNGMMRALETLENAKSLPASVFPNAGIADYVD
GEYRFGASPEYFGKMAVKFADMGARIIGGCCGTTPEHIAEISASLSGYVPVTLPEPIEGE
IERIVIHEHLEQVPVQERRGEPTLVDLVKERHTVIVELDPPRDLDITKFMKGAEALKRAG
ADALTLADNSLAVTRMSNMALGHLVQNRIGLRPLIHIACRDRNLIGTQSHMMGFDALGID
HVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKAKFVVGAAFN
PNVRHLDKAVQRLEKKIASGADYVMTQPVYDPELIVRMREATKHLDIPIFVGIMPLASGR
NAEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVQIGKELLDVAAEHFKGIYLMTPFMF
YDMSVSLTEYVWEISGRRLSHLFH
>A9VH39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides (strain KBAB4)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6A6A1B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dothidotthia symphoricarpi CBS 119687|TrEMBL
MHISQKLALARAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDITWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMERSKLDEALRDAYQAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVEYIREKYGNHFDIGVAAYSEGCDDNTDVDELIDHLKEKVDAGATF
IVTQMFYDVDIFLRWVEKVRAKGIDIPIIPGIMPIHTHAAFMRRATWTKCNIPPHWTEAL
EPIKNDDVAVREVGRDLIAELCRKLIDAGIMHLHFYTMNLAQTTRMILEELELLPGNTSP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAFGELDS
YGVGLKGTNEQNIKLWGTPTSIQDVSNLFVRYMEGKVESLPWSEQAITNEAGSIQKDLMD
LNQRGFLTINSQPAVNGAKSSDPVFGWGPNNGYVYQKAYLEVLVSPEYIAEVITRIERDA
DFTYYAVNKEGDLKTNAPGEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGDQW
ANCHASVSPARYVIQELMDTWYLLNIGEWFVSRRLHNDFHVNGGIFHLFDGLKVANMEKA
LYNPSVDVPTNGHEATNGDSGKTNGTNGVTSEASGEEKNKPELVDAAKVGTGEAINGVKN
TTLSA
>A0A0F3UFQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPLGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5B1LCC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides humilatus|TrEMBL
MTTGRGRSLGEIIRQGERSFSFEFFPPKDDAGETQLWDAIRALEPYNPTFVSVTYGAGGS
TRDKTVAITGRIARETSMVPMAHLTCVGHTRDELEGILDLYIAEGVYHVLALRGDPQEGP
RADWTPTEGGLNYALDLVELARSRGDFRVGVAAFPEGHPGADSLDVDADRLVAKANAGAE
FAVTQMFFRASDYFDLVDRVRERGVDMPILPGIMPILNLSAIRRQGELIGTSVPDEIVER
ITAAGPEPEKVRAEGIKIAAELCEDLLDGGAPGLHFYTLNRSKATLEIFEALRITV
>A0A366EY40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rossellomorea aquimaris|TrEMBL
MKPLLEALKERILIADGAIGTLLYSYGVDRCFEELNLSHPNEVLKVHKEYIDAGADIIQT
NTYGGNYQKLSRYGLEDSVKEINTAAVRLARKAAGENTYILGTIGGIRGIKQNVSLEEIK
RSFREQLYCLLLEGVDGILLETYYDFDELTTVLNITKREADIPVIAQVSLHETGVLQNGM
EIKDALQQLELLGADVVGINCRMGPFHMVNSLEEVPLPKRAFLSVYPNASLPNYEEGRFY
YSAEPDYFGDISNELRLQGARIIGGCCGTTPDHIRSVAGRLKSREPVKGKVVKAKKAVQL
SSPSIKGNLLHEQVREKKTIIVELDPPKHLDTKLFFQGAEALKEAGIDALTLADNPLASP
RISNDAIGSLVRSKFDLTPLVHITCRDRNLIGLQSHLMGLHTLGIHNILAITGDPAKIGD
FPGAASVYDLSSLELIELIKQNNEGISFSGKSLRERTQFSVGAAFNPNFRHLDASVKRLE
KKKNAGADYFISQPIFGKEQLIQVHEATKHLDVPIFIGIMPLISSRNAEFLHHEVPGINV
PEETRQRMKEAGSDPVIARAVGMEIAKDLLDTAIDLFNGIYLITPFVRYDMSIELIHHIQ
EKTNTEREVPYGHHFV
>D5BKM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zunongwangia profunda (strain DSM 18752 / CCTCC AB 206139 / SM-A87)|TrEMBL
MKVTEHIENAKGKTLFSFEIVPPQKGKNIQELYDNIDPLMEFNPPFIDVTTSREEHIYIK
REDGLLERKITRMRPGTVGICAAIKQKYDVDTIPHVLCGGFTKEETEYVLVDCHYLGIEN
VMALRGDAMKHQRYFEPTTGGHCYANELVGQIKDLSKGKYLNEVIDSDNHADFCVGVAGY
PEKHLESPSLETDLKKLKAKVDAGADYVVTQMFFNNQAYFEFVEKAKQMGINVPIIPGIK
PIAVKKHLQLLPHVFSIDLPQDLIDNVEACKNNKEVREVGIEWAIQQTKELKEAGVPVLH
FYSMGKSSNIKKIAEAVF
>A0A2H0FPT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriales bacterium CG18_big_fil_WC_8_21_14_2_50_31_20|TrEMBL
MRVTEHLDRANETLISFEIIPPKRGGDIKQLLSVLEDLVKYNPPFIDITSHAAEILYEET
ANGGFNMKIKRKRPGTLGICALIQNKYGIDAVPHVICNGFTKEETEDFLIELRYLGIDNV
LAVRGDDSGYKKPIKFGRSTNEFAEDLVKQIYNMNNGIYVEDTLLNADKTNFCVGVGGYP
EKHFESPNIDTDIKHAKAKVDAGAEYIVTQMFFDNKYYYNYVERCKAAGINVPIIPGLKM
ITSKNQLTSLPKNFHIDLPAELVNEISETKNEHIVEIGVSWTAKQVEDLLNNSSPAIHFY
IMQNSNPINLLMKKLNL
>A0A376TZC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MPKPANWWSEYCHGYGEDLSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1S1CBD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC061D12|TrEMBL
MTTVHPALSFELFPPRSHASCESLLHTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSNAE
LHRIGVDYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEY
A
>A0A162I9I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ascosphaera apis ARSEF 7405|TrEMBL
MTQLTYDVDAYNKFEKMLRVHESGVFKSIPIIPGLMPIQSYNNLTRVTKLSHVHVSEEIL
EKLKAVRADDEMVKKIGVDLLCDIIKGIQEGGAQAGPRGFHFYTLNLEKSVTKILERCNL
LRQENGHQEQRLNGTTEGLAIEAATSQNQVILDHPDTNRSAQTLETTASSIALTTLTPTT
QQDTLLQISEGVGSLGREATWDDFPNGRWGDPRSPAFGEIDGYGPSLHVGPNEARKLWGY
PVDENDISSLFLRHIRGELSVVPWSEGGGGDLQEVEGEASPALSPETAVIREELIELIEK
RGWWTLASQPAVNGVRSSDKIFGWGPPGEGFVFQKAFVEFFSPKQSYETVLKPLLKQYAG
EEEITWFAVNAAGEFTSSSNLTSQPQSPSSSPLSPSKRNSHNSNAVTWGVFRGKEIITPT
IIEEDSFKAWGEEAFRIWDEWRRVFPKGSATEKFLGKMKEEAYLVCVVGQRFGAGTERRI
SLHA
>J6UHF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum sp. PH10|TrEMBL
MSTELRPSRVPHHRNGMRVSFEFFPPKTEEMEKTLWESVTRLAPLSPAFVSVTYGAGGST
RERTHATVKRILDETGLTPAAHLTCVAATREEVDDVVRGYVAAGVRHIVALRGDPVGGIG
TPYAPHPGGYVNAADLCGGIKRLAAAEKVEIEVSVSAYPERHPESPSDEADIDMLARKVD
AGATRAITQFFFDNDLYFRYLDKVRARGISLPIVPGILPVQNFKLAQSFAAKAGASIPSW
LADRFAGLDDDPATRKLIAAAVAAEQVFDLVDRGVTEFHFYTMNRADLVYAICHLLGLRP
IGASAPAATAAAEAVA
>A0A417AEL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM46-18|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNVLCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A3S1HHI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M5C.F.Ca.IN.020.29.1.1|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFAEMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFD
GLQKDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A2S7DN25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. hederae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDT
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLIGR
>A0A1G0GNX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_36_30|TrEMBL
MEVTPLSFEFFPPNTTDGIEKLETVATSLNLFRPDYFSVTFGAGGVNREKSFHTIRTLQK
KNYDIAPHLTCIDLSKEMARDIILNYKKLSISKLVVIRGDLTPEMPQNIGDFHYANELVK
FIRDETGNYFEIHVAAYPEFHPQSVEINTALLQFKNKIDAGANSAITQYFFNAEGYFQFL
KSCEKLNIRVPIVPGIMPIFNFEKLIRFSKMCCADIPLWLYKRLESYRHDEASIKAYGIE
VVTKLCSDLIANGCPALHFYTMNQLEPTKTILQNLGYADYQESRAFTESSLSLAG
>A0A7Y7J8P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMEATGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFFTLQLGF
DAAKHQEAIHWMRRQASPKPMLACLMSLTHGRAAMLDHVAGVTVTLSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALEARIEHWQTQVQSMEQWTPA
WHASWQMPGLPAVTFHPPQAGWRLGESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPLWATRVGAQVLHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A7G8VNA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. PAMC26660|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYVRKPQFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFHYASDLVEFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
VRKLGIDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDIASIKSFGLDVV
ADLCARLRDGGAPALHFYTMNQSAATLALLERLD
>E8MTI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. infantis (strain 157F)|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A3E1US53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSAERFAAMEAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQMQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSRQAAPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAKSK
AFALARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVYASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPMWATRLGAQVLHKVEHAVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAMRQTELLTERLIPCIELETRHRSSWPQWFQAQTP
RQFSSQPAPRTQPES
>A0A7K6CYC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Origma solitaria|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A0B4G5W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium anisopliae (strain ARSEF 549)|TrEMBL
MDKITDKIAALPADREYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSKRLVDKALEDAKALGIRNILALRGDPPRKEE
YCDAEDSEDDGQQDFTWAIDLVKYIRRKHGDYFCIGVAAYPEGHSDESHPQDQSLEHDLP
YLVDKVQAGADFIMTQLFFDISAYDHFEKTLREHPSGAFKTIPILPGLMPIQSYQMIKRT
TKLSHAKMPPAIMDRLDAVRGDDEKVKLVGVDIVSELIDQIRKIKNRTPGRRGFHFYTLN
LEKAVSFIVERTGLIPRESDNEEALIDDGTLAPPAIQVNGTRASTHSRTSRRHSSVGSDP
YNRVIVAGQPPSHPEWEATGQEAGVPAESINSRANTLAISEGEGVLGREATWDDFPNGRF
GDSRSPAYGEIDGYGVSLHMSVNQAVTLWGSPTSRQDVNNVFVRHIKGEISAIPWSEEGL
SPESSTIQSRLVEMNGKGWLTVASQPAVNGISSSDRTFGWGPVNGFVFQKAFAEFFLPSA
DWHTLAEKLKGSDYFDSVCFYAANAKGDFVSSDISGGRSTRTVAASTNAVTWGVFPGKEI
VTPTIIEEVSFKAWSEEAFGLWGEWAKVYGRGSESEKVLSGIRSDYWLVNIIHHDFIDRE
ALWKLLLE
>A0A4V5RM28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. F13|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A1E7ISG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium C00003107|TrEMBL
MHILDIFSANPTTFSFEFFPPKTDKAANRLYETIRQLEPLKPHFTSVTYGAGGTTRERTH
ELVMRIQEQTALDPIPHLTCVGSSAAEIEQILTTYAEAGVSNILALAGDPPPEQPNYDRS
QDAFPQAADLVRYIRQFNERGLHPDKRGFGIGVAGFPEGHPSTPNRLLEMDYLKAKVDEG
ADYICTQLFFDNRDFYDFRERCLLAGITVPIIAGVMPIASIEGMKRMADLAGGTRFPAAL
LRSIQRCQDDAEAVRNIGIHWATEQCRDLLDNQVRGIHFYTLNNSDATKLIFLRLGLKTQ
>A0A3D9LGR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citricoccus muralis|TrEMBL
MSSPNPTPTDSGSPSVITDPSLEMTGKDKDIDALREAAALIPAGTRINVTFLGNEDLGMR
VKASSAAKELGYVPVPHISARRLTSEAELVEFLTALRDQVGATHAFAVGGDPSEPMGPYG
ASVDLITSGLLKEYGFTDISIAGYPEGHPDISDAQLWDALESKYASLQEQGLNGTILTQF
GFDVDPVFAWIKEVRRRGIDLPIRIGVPGPAGIKRLLTYASRFGVATSAGIAKKYGFSIT
NLLGTAGPDKMIQDLDAGLTPAEGDVKLHFYTFGGTKTTAEWIKDYQAKH
>A0A2T6AKL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gramella gaetbulicola|TrEMBL
MKITEHLQAAKDKTLFSFEILPPLKGQNINSIYESIDPLMEFNPPFIDVTYHREEYVYSE
KENGLLEKKIVRKRPGTVGICAAIQSKYGVDAVPHILCGGFSKEDTENFLIDLDFLGIKN
VMALRGDAVKSETYFKPEKNGNCFAKDLVDQIYDLNAGKYLDEVIEKGHNTDFCVGVAGY
PEKHMEAPSIDKDIQRLKEKIEAGAEYVVTQMFFENDRYFDFVEKCRESGIDVPIIPGLK
PIATKKQLSVIPHRFHVDMPDCLIREVEKCKDNAAVRQVGIEWCIQQSKELIAGGVPVLH
YYSMGKSTNIQKIATAIF
>A0A167D496|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sugiyamaella lignohabitans|TrEMBL
MQNLSLRLQRMSKLGNLFVTVTWGAGGSSAQKSLELAGLCQQELGIPTCIHLTCTNMDRT
ILDGALERAKEMGIRNILALRGDPPRGKEYSSIDHEKEGGEDDEVEFKYAIDLVKYIRAK
YGDYFCIGVAAYPEGHVDGVDSSDQNPDKDIPFLVEKVKAGADFIITQLFYDTQKFLLFE
QKLRDHPSHVFDNIPLIPGLMPINTYSSFVRAAKLSHASIPPQLTARLDEIPVGDDEQVK
QFGVDVVTDIIQNLIIGSHGRIRGFHFYTLNLEKSVALILEKSGLLQVDDEDESGHTTGS
TVDSNDAVRRGSAIVEDEELTVANLHPGHKSVSRRRSSLLTHNRLITADSDAISGPLKAG
KSSESLKDDSISEKEAGIKSSQSSTTNDVLAISSGEGDLGREATWDDFPNGRFGDSRSPA
YGEIDGYGPTLHVDPTKALKLWGYPVDISDINNLFARHIRNELDILPFSDQTLSAETALI
QEELLQLINKGYLTVASQPAGNAIKSTDRIFGWGPPGGRVFQKAFVEFFVSDEEWQKLKP
KLDSLGDGTLSYYEGTYEHDKIQHTNLTPGSSNAVTWGVFPNREILQSTIIEEESFLAWR
EEAFSIWEEWRNLYKPKTASYDLLDHIYKTYHLVSVVHHDYFDESALWNVF
>A0A354LZC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprobacter fastidiosus|TrEMBL
MKVIDLIKNSPTTAFSFEVLPPLKGNSIEKVFNTIDTLREFDPKYINITTHRSEFLYKDM
EGGLYKRVAVRTRPGTVAVAAAIQNKYQIPAVPHIICSGFTQSETEYALIDLSFLGICDL
LILRGDKAKHENRFIPTPEGHAHAIDLQAQVNRFNEGYFLDGSKMSLINTPFSYGVAGYP
EKHDEAPNPDSDLFWLKEKVKAGAEYIVTQMFFDNEKYFSFVDRCKSEGIDVPIIPGIKP
INFRNQLTVLPKVFHVDLPEALASELRKCKTDEEAKEVGVEWCILQAKELKEKGVPSIHF
YSMMATESVKRVARQVY
>A0A2W5R310|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas taxi|TrEMBL
MTFSVNQLEEARRALDAPLYADVGGDVDVSFEFSPPKTDKAEETLWQSIETLCPLGPRFL
SVTYGAGGSTRDRTHATVARIARDTDVPAAAHLTCVEATREEIDAVAQEYWAAGVRHIVA
LRGDPPAGATDYAPHPGGYENAAALVAGLRRLHPFEISVAAYPEAHPSSRDQADDLDNLK
RKLDAGANRAITQFFFEPETFFRYRDAAAAAGITAEIVPGIMPIGSFAGVSRMAAMCRTD
VPGWLVRLFDGLDQHPATRQLVAATVAAELCRKLYAGGVKQLHFYTMNKAELSFAICHLL
GVRAGQAQERAAA
>K0NB41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula toluolica (strain DSM 7467 / Tol2)|TrEMBL
MNALNTESRLEKVLKAGHIGVTSECGPPRGSDAQEVKKKGLLIKDYVDAVNVTDNQTAMT
RMSSLAACIHLKLMGIEPVLQMVTRDKNRVALQSDILGAASFDIPNMLCLSGDHQSFGDC
AQGQNVHDLDSMQLVQTVRYMRDEGKFLGGDKIKRPPKMFVGAAANPFADPFEIRVPRLA
KKIACGAEFIQTQCIYNLDKFKEWIRLAVERGLTEKTFIMAGMTPMKSVGMAKYMKNRVP
GMDVPDEIIKRLAGVAKDKQAQEGIDICVEHIQELKEVTGVSGFHIMAIEWEEKVPEIVE
RAGLYPRPEL
>A0A4Y8V3Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium LSUCC0112|TrEMBL
MDRQNNEPRFSFEFFPPRTDVGVEKLRDVHRELAALKADFFSVTYGAGGSTRDGTRQTVT
SIKQAGSDVAPHLSFGGSSKEDIAALLNDYKNMGIHRLVALRGDIPSGTGVASQYYYANE
LIEFVRETTGNHFHIEVACYPEIHPQSDSYDSDLKYFKNKVDAGADSAITQYFYNPDAYF
YFVDACNKAGITIPIVPGIMPITNFTSLQRFSNNCGAEIPRWIRQRLQSFGDDSNSIREF
GIEVVQTLCEDLLAGGAPGLHFYTMNQTEPVRQIWQQLGLRA
>A0A5B7WSQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glutamicibacter creatinolyticus|TrEMBL
MPGSVAPPSLSYELYPPVNREVAESVYHSIEQLADTSPDYVSVTYSGTPARRAQSLALIE
HLVTQTKLRPLAHLTCVGESAQSLRVLIRHFIALGVRGVLALRGDLPQDPQGWRGEFPFA
RYLIELIRQVEDEHAASLAGGRLGVGVASYPHRHPESPSFEHDIEVLLGKQRSGADYAIT
QVYFQPEDYRGLLAAARRAGVCIPIIPGIIPLNSLRRLNRLAALTGVQPDPILAHALQSA
TSDAERHRIGVRWAVDLARAAFDDGAPGLHLYTFNDHRGSLDVIEQLQLPGARSTLAQSW
AAHSGA
>N6V9F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium freirei PRF 81|TrEMBL
MMAQIDENPLGAGLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAI
FSGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQGDVLGAAAM
GVCNILCLTGDGVQVGDQPGAKPVFDLDSMSLLETVRTMRDEAKFLSGRKLTSPPKVFLG
AAINPFAPPHDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLAEKCFILVG
VGPLASARTARWMRSNVPGVHIPDEIIRRIEGAADQKKEGKQLCIDIINEVKEIEGVSGI
HVMAYRQEEYVAEIVHESGVLRGRRPWKHETSRSDVLVAERLGHIREGQEERQQEMAEAA
AHHPQHKAN
>A0A6J4X8R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius sp. associated proteobacterium Delta 1|TrEMBL
MIVGDLKPLAEIVSAIKEYKQVLVLGCGSCVTVCLSGGEREAEQLRHELSQIRHYEDTPP
KFVVDSILRQCEEDLVTDYHTIPEGTDAILSLACGAGVQTLGDAFDPLPVISALNTTFLG
ASAKPGIWAEMCRGCGDCVLNFTGGICPVARCAKGLFNGPCGGSHNGSCEVGLDTPCAWA
MIYFRLKRQNKLHLLEEIRAPKDWRPGGAGGPRKRVRIGLGDGTK
>A0A8H9KUS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium soli|TrEMBL
MKIVDHIKNAKGRTLYSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYLYKQ
HASGLLERVAYRKRPGTVAICAAIMSKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTVGGHAYATDLLQQVVDMNQGSYLHEDIGSSEKTDFCIGVAGY
PEKHFESPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVNKCRENDIHVPIIPGLK
PLTSKKQLITLPRIFHLDIPEDLSDAVEACKTNADVRQVGEEWLVQQCKELIDFGVPVLH
FYTMSNPGPTKNIVEKLV
>A0A6N7WAQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. BL-380-WT-2B|TrEMBL
MSSLLQQTLEAGKFAITAEMAPPKGTDFSHILEIADLLKGRVQGVNVTDYQSAAVKASSL
AMCVELEKKGLESILQMTGRDRNRIAIQGEMLSAGHFGVKNMLALTGDHTTTGDNPEAKP
VFEMDSVSILQTAEVLMSGQDLAGNELKGAPDFYLGACVTPVFDPIEVQLIKMRNKIKAG
AKFFQTQGVFDIEVMREFKELTKDMDCYVLAGIIPLKSAGMAKFMNRSVPGISVPDALIE
RLTEAEDKAAEGIRIAGEFVAQLKEEGVCDGAHIMAIGAEENVPKILDVAGL
>A0A1V6AWZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium ADurb.Bin151|TrEMBL
MQENRFKEALLNPSVFPVTWELVPGRGAREAAQDKALDLARQAVSNSHIYALTLTDNPGG
TPAMSADFMGSEIVRLGIEPLVHFTCKDKNRNAMESSLYALDRAGVRNLLVMSGDYPVSG
YQGRPAPVFDLDPIHVLQLISEMNKGLEYPGMKGTTRHQPADFFAGAVVSPFKATEAEQI
IQYSKLKKKIEAGAQFIVTQLGYDARKFHEVLLYMKQNGFSIPLIGNIYILPFGAAKMMN
RNDLPGSVVTDKLLADLDHEKNAPDKGQGARILRAARMYAILKGMGFSGVHIGGHNIKYE
QVDAIVEIGESLTSQWKDLVQYFDYPIEGGFYYYEKDPETGLNREAPVKLEDQLPDVKIG
CSYAFSRFFHRFMYEPGKNLYGFMKGLCGKIQGTIMEGPFHKMEHLTKAVLFDCRDCGDC
ALIDVAYLCPMSQCPKNQRNGACGGSYKGWCEVYPGKRPCVYVRAYARLKKYGEEGQLSG
EIVPPCNWDLYQTSSWINYYQGKDHTSQKFSNKPS
>A0A5B2YXJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. GDX7P459A|TrEMBL
MSRLLNQLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVESIHRSYIEAGADIIQT
NTYGANFEKLRRFGLEHKVKDIHKAAVAIAKRAARPDTFILGTVGGFRSLQQEELPLSTI
QYHAENQIDTLVEEGVDGLLFETYYDLEELTNIVTTTRRKYDIPIIAQLTASNTNYLVDG
TEINKALQQLVACGANVVGLNCHHGPHHMQRSFSHIELPETAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPQHIAYIKSSVKDLKPVKNKNVIPINRQT
NRAVTHTYKHNLTTKVKNGPTVIVELDTPKHLDTDLFFENIGKLDEANIDAVTLADNSLA
TVRVSNIAAASIIRQRYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMNYFITQPVYSKEKIKEVYEATKHLNVPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLSQFKAVRDDKEKTKALSLRLSKELIDTVHEYFNGLYIITPFQRIDYSLELAAY
SKAITQNKEAIS
>A0A851GFR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceaniferula marina|TrEMBL
MQSMREILTTSAEHPGSSFPIGMELVSTRGTMEEIKAVKAREFAMELAATDRIDWVSITD
NAGGNPMLAPAALGKPLLENNKEVAIHLSCKDFNRNGLESVAWQLNSEGFHNILALSGDS
PIDGHDGQAKPVFDIDSVGLITMLREMNQGLKVKAPGNTTRQLGMTRFFTGTVVNNFKRH
ESEVIPQYLKLDKKIENGARYIINQIGYDARKMDELLRYMQRQGHQQVPLVGNVYVLNPF
VAQIFHTRKIPGVYVNDQLLHIAEKQQQSADKGRAFFYEFAAKQLAIYRGLGYHAGYLGG
VHNYNAVDQILNIEQSFSGDDWKQFAREFSFSHPEEFYLFDQDETSGLSSNELNPSYLKS
LENRSGRDLSYSLSKQFHSLMFTPGKGLAPLCTRICQNAKDPSQGPAWMRAVERLSKNLL
FSCKDCGDCSLPETAFLCPESQCAKNQRNGPCGGTRDGLCEVADKACIWARAYDRLKPDA
EELQLLKHVPTLQDQSLRGTSGWANCWLERDHIAAKKK
>A0A851GEY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceaniferula marina|TrEMBL
MHIQDILKGPEPTFSFEFFPPKNNEASNALYEVIRDLSSCKPSFVSVTYGAGGSTRELTH
DLVVRIKETTSIPPIPHLTCVNHNEEEITQTLSRYASVGIGNILALRGDPPANLTDYNPA
NDSFQHAADLVRHIRQFNESGQHPDPRGFGIGVAAFPEGHPDTPNRLKEMDYLKAKVDEG
ADYICTQLFFDNHDFLDFRDRCRLAGIEIPIIAGIMPVTSAKGIHRMAELAAGARFPARL
LRALNRAGNKQESVQRVGIQHAAEQCAGLLDAEVDGIHFYTLNQSRATREVYASLGMA
>A0A6P0UKW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptobacterium flavescens|TrEMBL
MKVIEHIGKANGKALFSFEILPPLKGQNIQSIFDGIDPLMEFKPPFIDVTYHREEYVYKE
MENGLLQKKVVRKRPGTVGICAAIQNRYGVDAVPHILCGGFTKEDTENFLIDLNFLGIDN
VVALRGDAVKSETYFKPEKDGHPYASDLVKQIVSLNKGEYLDEDTQNTAKTDFCIGVAGY
PEKHVEAPSLDSDIHFLKKKIEAGASYIVTQMFFNNDSFFRFVDKCRKAGITVPIIPGLK
PIATKKQLNLIPHRFNVDLPDELINAVIKCKDNKEVRQVGIEWCVAQSKELVLKGVPVLH
YYSMGKADNIKAIAKEVF
>A0A3G6MGH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. G0201|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYRNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERKITRMRPGTLGICSAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTKGGHESAMDLVHQINDLGRGKYLHDEQACEENNKFCIGVAGY
PEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVTKAREMGITVPIIPGIK
PIATKRHLKLLPQVFKIDLPEDLINAVESAKNNEAVKQIGVEWAINQCKELLDFGVPVLH
FYSMGKSDNIKKVAGELF
>A0A2S5TFU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solimonas fluminis|TrEMBL
MGQEITFSFELFPPRTPEGWQKLPALVQKLASVRPAFFSVTHGAGGSDQHGTYEAIMQVV
EHSGIEAAPHLTCVGSTRDSIAALLQRYREAGVRRIVALRGDLPPDLQPGEAPGEFRYAS
ELVGFIRERHGDHFRLEVAAYPEMHPQGITPAQDFEHFRRKAEAGAHAAITQYFFNADAY
FDFVNRCEQAGLSLPVIPGIMPITNFAQLARFSAACGAEIPRWIRLRLEQLQDDKPALLD
FGLDVVTQLARTLLDNGAPGLHFYTLNQSEPTLRLWKNLALPMPLAA
>A0A539CXB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beijerinckiaceae bacterium|TrEMBL
MNEMQSCSFPRASRTVCPDICVSFEFFPPATEAMEATLWESIKRLAPLGPSFVSVTYGAG
GSTRERTHATVARIVKETPVKPAAHLTCVAAAREEIDAVVSDYWNIGVRHIVALRGDPQD
GPGTKFCPHPQGYANSAALVAGIKQIGNFEISVATYPEGHPESVSADADIDVLKAKIDAG
AHRAITQFFFENEIYLRFLDKVRARGIDIPITPGIVPVQSFQQTTKFAKRAGASVPQWLA
DRFEGLDDDPQTRKLVAATVAAEQVLDLVDHGVRDFHFYTMNRADLVYAICHLLGLRPKL
EQEAA
>A0A255T1W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. P5-92|TrEMBL
MTVIELINKDKDKRHFSFEVLPPLKGTGTDKLFATIDKLKEFDPLFINITTHHSEFVYHE
MDNGLLQRQRIRRRPGTIAIAAAIQNKYGIPVQPHVICSGATVEDIEYELLDLQFLGISN
LLLLRGDKAKEDPRFIPTPGGHEHTTDLIRQVNRFNEGFFADGTPIKCPGEKFDYGVACY
PEKHEEAPNLEMDLQHLKEKQDLGADYAVTQLFYDNQKYFEFVEKARQAGITIPIIPGIK
PFAKLSQLTIVPKTFHCDIPQSLALEAIKCKTDEEARQLGVEWAVAQCKELYSHGIHNIH
FYTVSAVDSVAEVARRLL
>A0A4D6YCE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MKNYHKYHQDILNQKLENYQNIIQCSFEFFPPKNLIAEKRLWSSVNEISSLKPNFFSVTY
GANSGERNKTHHFVKKINQITGVITAPHLTCIDTTSNQLRKIAKNYWDDGIKHIVALRGD
TLNKNYQHKMYALDLVVLLKKIADFDISVAAYPELHPESKNIQSEIFYLKNKIDAGASRA
ITQFFFEIESYLRFRDACVKNGIQVDIIPGILPISNFQQIKRFSSITNVHIPKWIFKMFD
GSENNLMTQKIIGSSIAIDIVKNLCHEGVKNFHFYTLNQSDMAYSICHILGLK
>A0A8J8FEQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnovirga soli|TrEMBL
MKVTDHIQQAKETLVSFEVLPPLKGKSITSIYDHLDPLMAFKPSWINVTYHRSETAFKKR
ADGTFEKVEVRKRPGTVGICAAVMNHYKIDAVPHIICGGFTMRETEDALIDLNFLGIDNV
LVLRGDAAKNEASFEPEPSGHQYAIDLLKQVSDLNHGVYIDEDIRNGGKTKFCIGVAGYP
EKHFEAPNPEIDLNRLKEKVAAGAEYIMTQMFFDNQKFYDFVKACRDNGIDVPIIPGLKP
ITSKKQLSVLPRIFHVDIPTDLSNEIMKCKSDEDCEKVGTEWLVQQSRELKAFGVPVLHY
YTLGKSKVIANVVKEIV
>A0A1L8CIS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MRKQSFSVEIEANPGDLRQMKHYLHKWQPDFVSISNLSRYSYEEMVQCARYIQTDLNIPV
VIHLTGLTHTKEQIKKAFNELMDLNIRNFLLVRGNIHHNMHIEDDFNYASDLIKYVNQLD
TDSKINVVAGCYPDIHVLADSLTEDIEYLKQKVNSGVDSLISLMCFDNKRIYKFLDKSRE
FGINVPIRIGIMPITDPFKRHYLTHNDVKMPEFSEEEDNLLENGINYAVNQINDLYEHNV
NGIHLYTHNDWMVSDRVFENIKQNL
>A0A2R6IDQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QS_4_69_31|TrEMBL
MSLRTRSATDREGLEHLLTGARFELMPFESFEEEITHLPEDATIAITTSPQLGIGATVER
TEEAREQGFDVVPHIAARYVEDRDHLTEIADRLTAAGVTDIFVPGGDREEPAGEFESAYD
LLVALNELGYEFEEVGITGYPEGHDFLSEETLAESMASKEPYATYIVTQLCYDPDAVIEW
VEDVRARGIDLPVEVGIPGVMNYQRLLEISQKVGVGDSIKFLRKTTGVFGFVRQLIGSRG
VYKPDDLVDGLAPYVGDEEYNIRGIHIYTFNQTPDTEDWRLGRLDE
>A0A808XMH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella sp. X13|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAEDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIVPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A3D1JHY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolinea thermolimosa|TrEMBL
MNEFLDFLANQKPVLSDGAMGTVLHARGASLDSCFDALNLTHAALVTEIHQEYIEAGSNM
IQTNTFSANRYKLARFGLESKLAEINQAGVELARRAIQATGRHVWIAGDIGPLGVRLAPF
GRVQPEQARRAFKEQAAALMEAGVDLIIIETMSDLFEIKEALQAVRELNPSLPVITSVTF
TRDDRTILGDSPARVARFLHDAGTDVIGVNCSGGPNQILRILKLMRAEIQGAYFSVMPNA
GWPEQVGGRIMYPAPPDYFGEYALSFCTVGASVIGGCCGTTPQHIQAMARALQNRPQGCT
QTSDIITLSSAEEAPLEERPTRLAQRLAEGKFVTAVEMDPPRGLSTHKLLAGASMLAEAG
ADVINVADSPMARMRMSPWAVCNLIQNQVGIETVLHFPTRGRNLLRVQGDLLAAHALGVR
NVFVVMGDPTAIGDYPDAMDNYDLVPSGLIKLIKQGFNTGVDHSGATIGQPTGFFVGCAL
NLLPQDPENEIKNLKRKIKAGADFILTQPVYDTAAARSFLKIVHAEFGGQLEVPILMGVL
PLYNSRHANFLHQEVPGILIPESILQRMTAAGEQGPQEGVRIAIEVVEELRSEIRGIYIM
PAFNRFDYAADLIEHFKE
>A0A1E4HMW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. SCN 72-86|TrEMBL
MTVRDLLATSVLVGDGAMGTMLHAAGNSLDQALPALTLTEPGLVRTIHDSYVGAGVDLVQ
TNTFGASRLRLAEYGVADDVARINAEAARLALEAAARADRPVLVAGSVAPAVSVHQRRRV
GADERRAAVREQVEVLVGAGVDVVMLETFGHLDELVEASEVALEVARRTGDVPVVAQATF
GTDHHTLSGHTPHELVAALAGLPLAAIGVNCTLGPQGCLAVLRELRSHTAMPLTVQPNAG
LPRRIAPARFEYDIDADYFVRYTRQLLDAGAALVGGCCGTTPGQLAAAAAAVAEYRAQRP
VMVVEPSRSPAVGVSRPGLFDSAEPLVGVELAAPTTGGVDETVALAADLREAGVGLVCVP
ATSGPRAQVNSVDLALHLHDRLGVTTLASVTTWDRTIMALQADLLGAHALGVRGVLCETG
TPPLVGDYPHVDGIWDVDSLGLIELLAGLNEGTDYHGLRLGTKTSFDIGARVNPGSRDPG
RAAAGALDKIAAGAQFLITRPIFEPTGLERVVGAVDGRVPILVAIRPLTGFDEADYLAHE
VPDVTIPDATLAALADAGPDAAAAGVDLALALAEQVRSMTRGIVVTGDSDVAATVRRLTT
GE
>A0A8G0LVF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MPLQYSFEITPNINQNNLDGLLKLNPEFISITDRNHDMDNLLQSIRIADYIHANSSVDVV
IHLTGIDKDEKGVQEMLDLMQQHDIDSVLALRGDKLSQNDTAVTFPHADRLVEFIKQQYP
HVNIVGTCYLNSSDEEMKWLRQKVEKGCTKLISQFSFDVNDYVEYLNQIQIDTPIWLGIM
PVISKSQAQRMLNLTHSTAPDELNALMNQHEDEFGEYGVQYTAGMIDQIKQAGANHIHLY
SLNNASNTKKIINKI
>N8PZ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP A162|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKT
FPSSVEKIIHYSGKSRDITDFETFLKLTQASGQKNLLLLTGDKLKGHTNSQAGTNRTRYL
ESVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEAL
KQAKAFLNRHRYPQNILACVMPLSLARANFMVKHKIAGIVITPHMLRVLAQEKQDGRTEN
TYKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVE
TKKELVPQLAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASFWENTPAAK
ALLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A1M3KHR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium 44-23|TrEMBL
MGLESKFLRKLAQPKPILSDGAMATVLHSNGIRFDDCFDALNLTQPALVADVHRAYIESG
SQMIQTNTFGANRFKLSEFGKEDQVKQINQAGVDLVRKVALASSLDILIAGDVGPLGVRL
APFGKVQLDEAYKAFHEQILVLIEAQADLIIIETMTDFYELREAVRAAKDIDSKIPIIAS
MTFTRDDLTLLGDSPEKVAKSIFALDVDVVGINCSGGPLQLLRILKKMKKVVPQALLSVM
PNAGWPEQQDGRIMYPAGPEYFGEYALSFWKTGAKVIGGCCGTTPQHIRAMADIISITEN
VDIANGIEFIQEAENPEMLESDEQSQLSKKMAHGDFIIAVEMDPPKGLSTKKLLAGASLL
ADSGADVINVADSPMARMRMSPWAVCSLIQKYTNIETVLHFPTRGRNLLRVQGDLLAAHA
LGIRNVFVMMGDPTAIGDYPEANDNFDLVPSGVIKLIKQSFNVGLDHAGSEIGQPTTFFV
GAALNLSANNRQLEVNHLFRKLHAGADFFLTQPVFDIEKTRQVINQIRGLAEGDHIRILV
GILPLVTDRHANFLHNEVPGIFIPDSIKKRMQKSGDNSAATGIEIAIELISGLRDQINGV
YLMPAFNRFDYAAEIIEKVRSF
>A0A1E9H9C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC061D01|TrEMBL
MSIQSPSLSFEVFPPNPAVGNEKIMAALKEMQDLVPHFISVTASNNKFNIEETTVRLADF
IRNDLHIPTIAHLPAVYLTKEMVTETLTALDKVGVHKVLALRGDILPDVEPQKDFVYATD
LIEYIKKEAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYD
FQDKCILAGIEVPIHAGIMPILNRNQVLRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSDTAHRIYQATHTFFNK
>A0A1H4YY15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas anguilliseptica|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVRQLD
GEIKVPAAPHLSCVGDSKAELSELLTLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADCYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTDSIQAYG
EQVITEMCERLLQGCAPGLHFYSMNQAEPSLAIWNNLKLPR
>R9J275|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 28-4|TrEMBL
MIIENIFKEKKPVVSFEIFPPKKEAELNNIDATLKTLAQLHPDFISVTFGAGGSSADNKT
VELAKKIKRDYGIEPLVHLTCISNSKEEIRQILGQMEDAGLKNVLALRGDMNPNVPAKND
FRYASELVAFIKEQGDFHVSGACYPEVHLEAPDGIADIRNLKKKVDAGAGHLVSQLFFDN
NVFYDFLTKVRIAGIDAPVEAGIMPVTNKAQIKRMVTMCGASLPDKFERILEKYGESKEA
LFDAGMVYAINQIVELISYGVDGIHIFTMNNPVVAGRICDGIKNLV
>A0A0K1QI83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens NCIMB 11764|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A162CCC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas luteoviolacea S4060-1|TrEMBL
MALSLQEKILDPNQGVYLIGTTPPKQGTDKEQVQTIATKLLNRLHEIEYDGVVIYDIQDE
SSRTDVPRPFPFKQTVDPCEYSQVVSELSKLDVITYKSVAQRDQSEFTQWLHKTKQDFGL
SNLVLVGSPSSKGDIKLSLPDAYQTLRDHQDDFFLGGVTIAERHASKRNEHERLIDKTTQ
GCEFFISQAVYDAQATIDLLTSYARTCRQQGIEPKRIILTFTPCGGEKTLQFMQWLGISV
PEATKWRMLDSDNTLKESIKICRENLDLILRSCAQLDVPLGLNIESLTNRKEEIDAAINL
YRLLKATMELKLAEKQIA
>A0A7R7GPA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiohalobacter sp. COW1|TrEMBL
MKTQQKYEKSYSFEFFPPKTEEGAKKLRLARSRLDKLNPNFYSVTFGAGGSTQEGTYETV
AEIIKSGGDAAPHLSCIGSTRDNIRELLQRYKDAGVRRIVTLRGDMPSGMRDTGEFRYAN
ELVEFIRAETGDTFKLEVAAYPEFHPQAPTAFEDLENFKRKVDAGANTAITQYFFNADAY
FRFVDDCERMGIDLPIVPGIMPITNYKQLARFSDACGAEIPRWIRQRLIAYGDDMESLGK
FGEEVVSALCQRLLDAGVPGIHFYVMNRSAPTIAIWKNLGLPVRD
>A0A8H7ZPX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olpidium bornovanus|TrEMBL
ACLGGRHEFSFAACPPTGFPNKGIINLYDRIERMYMLGPEFIDITWGAGGSTSQLTLEIC
ATAQSVYGLETCMQYLAVANCSLTCTNMHKDMIDRALKEAKDAGIQNILALRGDPPRGQE
SWTATEGGFSHAADLVRYIRNQYGDYFGIAVHFENPDREDDLCRLKEKVDAGADYIVTQL
FYDVDLFLKWVEDVRAIGIYGSFHRAVTMSKTFVPKTIRDALEPIKDDDQAVKDYGIRLA
>A0A834AG42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllostomus discolor|TrEMBL
MKLSKLEVPQSIRDVIEPIKDNDDAICNYGIDQAVSLCRKLLASGLVPGLHFYTLNRLKA
TTEVLKRLGMWTEEPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTRDWDEFPNGR
WGNSSSPAFGELKDYYLFYLKSKAPREELLKMWGEQLSSEKSVFDVFVRYLSGEPNQNGH
PVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPRVNGKPSSDPVVGWGPSGGYVF
QKAYLEFFTSRETVEALLRVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGRE
IIQPTVVDPVSFMFWKDEAFALWVERWGKLYDEKSPSRRIIQHIHDNYFLVNLVDNEFPL
DSCLWQVLEDTLELLNRPMSE
>A0A4S8PLG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycomyces paridis|TrEMBL
MTLGVPSVMPTKAAKVGDLLREGTPKFSFELFPPRDEKAEGVLWRTIRNLEQLGPDFVSV
TYGAGGRTREKTVETTDLINSETTLLTMAHCTAVDHSVAELRNLIGHFANVGVRNILAVR
GDPPGDPQADWVKHPQGILHASELVELIKESGDFSVGVAAFPEGHPRDLDWDTGVRHFVE
KCRSGADFAITQIFFDVEDYLRLRDAVAATGCDIPILPGIMPVTNIKQIERFAVLTGMVF
PEALAERLRAAGDDRDAIRDIGVEVATDMGTRLLAEGAPGLHFTTLNHSRSTRRVWQNLR
P
>A0A829RG33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 83444|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKARINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A840V921|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidocella aromatica|TrEMBL
MNQITPLPPADDLALSFEFFPPKTEKMDAELWETVQALAPLRPRFVSVTYGAGGTTRERT
HAAVSRLVHEAGLNAAAHLTCVGASREEILDIARGYWAAGVRHIVALRGDPPAGAGRFTP
HPDGFANATELTEALKRLAPFEISVAAYPECHPDSPSVQADLDNLKAKIDAGADRAITQF
FFSPEVFLRFRDRAAAAGISAELVPGILPIANAAQTRKFAAQCGTQIPPALDRLLDGLDD
NPQMRPLVAAMAAAGLCRGLYEEGVRQFHFYTLNRAPMTQALCHLLGRRASGWAHVAGAV
SA
>A0A368ZHW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella arenosi|TrEMBL
MKVTDHINKANGKTLFSFEIIPPKKGNSIQQLYNNIDPLMEFNPPFIDVTTSREEYLYIE
KDGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGINNV
MALRGDAMKHQQYFEACDGGHQFAKGLVEQIQNLNKGQYLHDVAEGHDKADFCIGVAGYP
EKHLEAPSLKTDLKRLKQKVDAGADYVVTQMFFDNQKYFQFVEAAKAEGINVPIIPGIKP
LAVKRHLQLLPQVFKIDLPETLIEAVESCKDNKAVRQVGVEWAVQQSKELQQAGVPVLHY
YSMGKSDNVKAIASQLF
>A0A7W1KB93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MPMTALTSAEISLPSAPDALRVRERIAALADTVDLVGLTDNHAGLPRMSPLAAVALAREQ
GVNTVVHVSCRDRNRLALQSQVVGAAALGSEGVLCLYGDPVDGVPRVKDLTATALIASAK
QWASPHDLAVGAVVNPFAPDQDRELRLLERKIAAGAEFLQSQMIFDLDALRSFLDRAAGL
LTSVRFYAGVALLRSERMADNVRRLPGCLLSDAAHRQISMGGGLDLATQFATELASTPGI
DALHIFPLGAETETREVAAAFRSARGVPARRR
>A0A1I8NDW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Musca domestica|TrEMBL
MICASTLIGSHRRRSRAQLIVITKVINNTHIAIKFSTQQMQKGKISTTMISNNISSTTLG
TPGSTATAQGAHILPAPKNATNHYEINIQFTEEQQRLSYYEETLTTTTADQRQLKNVINE
KIRNREFFYGLEILAHTYNPNYWLDYNALGPLLPLFTSIVWLGMDYCNIENLNEVEAIRL
ANKLNRHVRVMPHLSCYCLTETRLREFLNMNFPNVLSIRGDFFDKDQRYQHSSELVEAIR
RIRGDSISIGVAGYPEGHPECKSIEEDLGNLEKKVVAGADFIITQICFSSRPIIDYIKNC
RSRNIKIPILVGIFVPDNLRMLETILRLTKIHMPSEDLQEYHRHHDLGEGQFTEYAVRRA
VEMIDSILSSDEVEVYGLQFFSMNRFQNIPMVLEKIRKKHNK
>A0A1H4N5R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium GAS191|TrEMBL
MTQTKLSQAKPAKQANVPVSRLPGSNGVSVSFEFFPPKTPEMETALWEAIDRLAPLSPAF
VSVTYGAGGSTRERTHATVKRMIDETQLKPAAHLTCVAASRSEVNAIIRDYWAAGVRHIV
ALRGDPAGGAGARYEPHPEGYHWSTDLVTAVKAIGDFEVSVGAYPERHPESPTLFADVEM
LKRKVDAGADRAITQFFFDNDVYFRYLDVAQAAGITIPIVPGIVPVQNFKQTANFAKRTG
ASVPDWFAERFAGLDDDVATRRLVAAAVCAEQVLDLIDRGVTHIHFYTMNRADLVYAICH
LIGLRPALASDGTIEVAAA
>A0A1H5CU63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium GAS191|TrEMBL
MGDRAMMPASQVPQDVVPPQAQDTVPTQAQDIVSQIVAFMQRASMEATRPTPADAEMLSA
VLPHGTDIFLSAVPRRPRGEVIAAARAIRTAGLNPVPHIAARAYPSLEAAREHLARLRDE
ADIRALLVIGGDLDQPAGDILEARQLIESGVLPALGIERVGIAGHPAGHPRMSDEELESV
LVTKIAAAQSSGLEVEIVTQFCFEPATIIDWIAWLRRRGVNLPVRIGLAGPTSLMTWLNY
ARRCGVRASAEGLARRSGLVKHLFNAVAPDSILRALAQARQAELPSTDRLGDVSAHFYSF
GGIGPTARWVASAMHGAITLDKEGGFQVEHE
>A0A429WJY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. MHTC-1|TrEMBL
MRLPLSFEFFPPKTPEGAAKLRTVRQQLYARRPEFCSVTYGAGGSTHEGTFGTVREILGE
GVDAACHFSCIGATRSTVREQLAELKAMGVKRLVALRGDLPSGYGMGGEFHHASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVHAGADSAITQYFFSPEAYFRFVDE
ARKLGLATPIVPGIMPITSSTQLMRFSDACGAEIPRWVRLRLQGFGDDTASIKAFGLDVV
ADLCARLAGGGAPAIHFYTMNQSVATLALLERLGWDE
>A0A0X3X3T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces violaceusniger|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRADLRNVIGQYADAGIRNMLALR
GDPPGDPTGEWVRHPDGLNYAVELVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATEVCARLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>A0A3P5XN79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xinfangfangia humi|TrEMBL
MTAAPRISFEFFPPQTLDASFRLWETVRALAPMDPNFVSVTYGAGGTTRKLTHEAVGTIH
RNYGLNVAAHLTCVDASKAETLEIVESYAAQGVTEIVALRGDAPKGAGAWTPHPEGFASS
VELVEAIAKTGRFKVRVGAYPEPHPDAGHAGADVEYLKRKVDAGATSAITQFFFEPDTFF
RFRDACVKAGIGVPVIPGILPIISWEGAKKFAARCGTQVPVKLDEAFSRAVKDGREELYA
LAQCTQLCDRLLEGGVEDLHFYTLNRPELTREVVRALGIQPRVVLENVA
>W9CWW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. CcI6|TrEMBL
MWLWSVESYPVRMREPTAGHERPVRGFEMICEIEPPTRPDLTHARHQIGVLSPVTDAFLI
PDNHIGRATVSSIAVAHEVATMGGRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVHG
DKPTAGNRTGDLTVRAMMDEARAASEDPVFADMPAFRVGAAAGLRPLPTWKRAADFLFVQ
ISYSVDALLRWRDAHPVELPIYAGVMVLASAGMARRLAAAIPDIDIPDDLVQAVERDQAA
GVEAACDQVLRLRDSGAFAGVHLVPVSRYRQVATRLEDLL
>A0A674CES7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmo trutta|TrEMBL
MVQGKRSIPLDMYVLLVSQNVKTLSVGSSSMVNQVQRVEDTWRTCSKSDSSGASNSGGES
SKESSRSSTPVLDTDRTDRLRDKMRRRTESGDHWFSLEFFPPRTASGAVNLISRFDRMGS
GGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQTKAKITGYLSKA
KRLGLKNIMALRGDPMGADWEEEEAGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAE
SYDEDLRHLKEKMDAGADFIITQLFFRADTFLKFVRDCRAIGITCPILPGIFPIQGYQSL
RQLVKLSKLEVPDEIMRVIEPIKDNDAAIRNYGIEQAVGMCRVLLESGEVPGLHFYTLNR
EVATMEVLRQLGLWNEDPRRTLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFP
NGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEELTSEQSVYEVFTSYITAQPNV
AGHKVMCLPWNDDPLAPETNLLKNELDKVNRRGVLTINSQPSINGKPSSDPIVGWGPPGG
YVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFP
GREIVQPTVVDPVSFLYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDND
FPLDNCLWQVIDDMFELLDNPQEEQPAEQPNDEQSDKEQPGK
>A0A415MFE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospira eligens|TrEMBL
MKYTGTAGILYDRLKSEILVADGAFGTYYAKKYDTGSLPELANLQASDRVLAIHKEYIEA
GAKIIRTNTFASNTVCLGAGFDEVRNNIKNAVDIAREAVKGTDVLVAADIGPIPGENMNE
KEHIEKEYVDIVNVFKECGVDIFVFETFPELGFIDKAIENAGENGFVITQFAINQFGYSS
AGFSARKLIEEAGKNSYIDACGFNCGVGPGHMKKLVQSLINRNDKYFAVLPNAGYPQVVS
GRMVFDDNNAEYFSQIMRDLAEDGADIIGGCCGTTPEYIRQMVLKTADVVHKKNASIEEE
ISEKKTANDVSFYKGKEGRKLIAVELAPPLGIDDEKIMDAAFLMKESGVDVLTFPDSPSG
RTRADSILMAEKVSRETGMCVMPHICCRDKNAIAMRSQLLGAHINDINNFLVITGDPIPS
VVRASVKSVFNFDSVGLMNIISDMNQEQFAGKPVIYGGAINQGRVNFKVELERVKKKMEA
GATFFMTQPVFSDEDIDRLRQIKEQTGARILCGIMPFVSLRNATFMKNEMTGINVTDEIL
SRYRADMSKEEGEETGIQIAREIIAKTTDFVDGYYFSFPFNRVHMLKKIIGKNNQ
>A0A413YZ10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospira eligens|TrEMBL
MKYTGTAGILYDRLKSEILVADGAFGTYYAKKYDTGSLPELANLQASDRVLAIHKEYIEA
GAKIIRTNTFASNTVCLGAGFDEVRNNIKNAVDIAREAVKGTDVLVAADIGPIPGENMIE
KEHIEKEYVDIVNVFKECGVDIFVFETFPELGFIDKAIENAGENGFVITQFAINQFGYSS
AGFSARKLIEEAGKNSYIDACGFNCGVGPGHMKKLVQSLINRNDKYFAVLPNAGYPQVVS
GRMVFDDNNAEYFSQIMRDLAEDGADIIGGCCGTTPEYIRQMVLKTADVVHKKNASIEEE
ISEKKTANDVSFYKGKEGRKLIAVELAPPLGIDDEKIMDAAFLMKESGVDVLTFPDSPSG
RTRADSILMAEKVSRETGMCVMPHICCRDKNAIAMRSQLLGAHINDINNFLVITGDPIPS
VVRASVKSVFNFDSVGLMNIISDMNQEQFAGKPVIYGGAINQGRANFKVELERVKKKMEA
GATFFMTQPVFSDEDIDRLRQIKEQTGARILCGIMPFVSLRNATFMKNEMTGINVTDEIL
SRYRADMSKEEGEETGIQIAREIIAKTTDFVDGYYFSFPFNRVHMLKKIIGKNNQ
>A0A2D5ZDC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaeraceae bacterium|TrEMBL
MPEYKQDEVREAYEQQITALVDEGVDLLVLETFHHLREMRIALELARASFTGPIVAQMSF
QEDGHLLDGTAPERVAELLGTWGADVVGVNCCEGPAIVHDVATEMLRAGRPVSAQPNAGR
PRRLDQRMLYMATAEYFGVYARRMLKAGIRAVGGCCGTRPEHVAAIAAAVRMVGGGSARQ
AIGARKRGPETITVEGVTPMPTAEKSDFASKVMRVWKGRLDEGRRRRSPAGQEDFVVSVE
VNPSPGLSTDKPLKAARLLKDAGVDVINIADGPRAAVRMSNTALALEMRRKLETEVILHV
CCRDRNLLGLQSDVLGAHVMDLKNLVVITGDPPKMGDYPKATAVFDLDSIELLKLIDGLN
KGIDPAGKMVGEATSFFMATGAEPGAFDYERELGRLELKIKAGAEMVMTQPVYDPAVVEK
FLNDTRVMGVPVLLGICPLVSFRNAEFLHNEVPGMEVPQPIRDRMEAAGSGKTGIAEGVA
IAREMLDAFQDRVVGCYVMPQLGRYSTAIDVLRPLGYGGE
>A0A867ZLA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Icterohaemorrhagiae|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESA
>A0A149ULR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter malorum|TrEMBL
MSLSRLSVELIPRSEDALAQDMTSVQTLFPAADTLNIPDLMRFPLRSWDAAALTMPQFGT
VVPHVRAIDIAPGAPLPGSTLPGLKEVLVVHGDPPADLAHRTYPNSTESIIRRYRKEAPH
LRIYAAFDPYRRAPWRELEDIARKKDAGAEGFFTQPVFDLKLFDLCREWLQDEQVFWGLS
PVIGPRSRSYWETTNHVVFPKDFEPTLDANIQFAQSVLRQLSQDQGCAYLMPLRVKLDQY
LPPLMSALTA
>A0A502FQR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas nepalensis|TrEMBL
MNEMSPPSPKQAQAEAKTLGNWLSGPRVDALPSLTAMPAPLLSFEFFPPRTEALEAQLWS
CVKRLEPLAPRFVSVTYGAGGTTQARTHATVTRILRESSLTPAAHLTCVGATKEEVDAVA
RDYWEAGVRHIVALRGDAPSGANGYEPHPGGYAYAADLVAGLKRIGDFEISVAAYPEVHP
TASSPDDDLDNLKRKIDAGATRAITQYFFDAPTFLRFIDRAHAAGITVPIVPGILPVSNF
AQVAKFSAMCGARVPDWMGTLFDGLDEDAETRRMVAAVVAAEQVRLLQANGVDEFHFYTL
NRPDLTYAIAHILGARPQG
>A0A5A9ZHA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquicoccus porphyridii|TrEMBL
MMAPKVSFEFFPPQNLEGSFRLWDTIHALAPLDPRFVSVTYGAGGTTRDLTRDAVRTINK
ATGLNVAAHLTCVDATREETLAIAESYAEAGVTEIVALRGDPPKGSGRFVPHPEGFAHSV
ELIEALAATGKFTIRVGAYPDVHPEAKNPQADIDWLKAKLDAGADEAITQFFFETESFLR
FRDACAKAGIEKAVVPGIVPIENWKGVRNFAFRCGASVPAWLDDAFAKAERDGREDLLAT
ALCTEMCSELIDEGVDALHFYTLNRPELTRDVCHALGVVPRVQLENVA
>W5XH14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus H9|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSEEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHRS
>A0A317VZ42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus heteromorphus CBS 117.55|TrEMBL
MEKITDKIAALPPDTNYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDAPRSEE
YNIHGEDDSNRDFTFAVDLVRYIKQQYGDYFCIGVAAYPEGHPADNFQDGQDPERDLPYL
VEKTQAGADFIMTQLTYDLEAYTKFETRLRNHESGAFKTIPILPGLMPIHSYKILTRVTK
LSHVQVPPHILAKLEEVKHDDDAVKRIGVDIISNIVHGIRELPNSGQRGFHFYTLNLEKT
VSFILERCDLIPPYSEYDDGEALADGGNLSALDSSSYLAPNGAQIRNLTSRRSSVSSIPH
NRVIVDKLQASEASSNHSVTHEALALSAGLPAQPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVQPSVARRIWGFPVTREDISALFRRHVSGELHMVPWS
EGGAEENTSGLNAETAVIRSELLTLIDKKNWWTLASQPAINGVRSDDPIFGWGPPGEGFV
FQKPFVEFFCPDKDFQSVLKPLFQKHGHEKLAWFATNAAGDFESSLPGPNPDDADPIDIN
PANVNAVTWGVFRGKEIVSPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSASERFLDQTK
NDVWLVCVVGQEFGAGTEVGSEEEEDEVKWMWRELANC
>A0A2H0LTU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG11_big_fil_rev_8_21_14_0_20_43_6|TrEMBL
MTFKEKIQAHKFLLTSEVGPEKGIHADRLLQDAELIRNRVDAINVTDLQSSVMRLGSLTV
SFLLKQNGFEPIYQLTCRDRNRLALQSDLLSAAALGIQNILIATG
>A0A0A2HU99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp. Tol-SR|TrEMBL
MSFQKRLQAHEFVVLAEMHTPKGVNISRLMTDARRIKGRIDAVVIPDMDNGIMRMSAIAG
GVLMQQQGVEAIIHTYCRDRNRMALQGDILAAHVLGIQNLIVAHSEEMSQGDHSDAKTVA
DLDEIGLLGAIRQLQAGRDMAGFDLDGIPGFTVGCTMAPCADAAELEEELAAAAKKVEAG
AMFVITPPVFDLGHFAALLPKIKKLGVPIIPTVFLLKSLAIAQYIANSEPGAHISDELIR
RIRKSSDREQEGIQIAGETVAALKTMTEGVMIQTLGWEHKLPAILDIAGI
>A0A1F3PNM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium RIFOXYA12_FULL_38_20|TrEMBL
MKVINHIKNAQKTQFSFEILPPEKGANIQEIYDTIDPLMEFKPPYINVTYHKEEVVYKKH
PNGLLEPRTVKKRPGTVGISAAIKFKYDVIIVPHIICGGFSMEETENALIDLHFLGINNL
LVVRGDADKTTRSFVPDPNGHANAIDLIRQIKRMNDGKYVDDDLIATTPTDFSMGVAGYP
EKHNEAPNMDSDIRHLKAKVDAGADYIVTQMFFDNQKFYDFVKRCREAGITVPIIPGLKP
MSIKAHLNILPQTFHIDLPEILVKEIEKCETNAEVRQVGIEWGIMQSKDLIKNNVPIIHY
FTMGKSDNIRRIAEGAF
>A0A1Y3G669|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter malorum|TrEMBL
MSLSRLSVELIPRSEDALAQDVASVKTLFPAADTLNIPDLMRFPLRSWDAAALTMPQFGT
VVPHVRAIDIAPGAPLPGSDVPGLKEVLVVHGDPPADLAHRTYPNSTESIIRRYRKEAPH
LRIYAAFDPYRRAPWRELEDIARKKDAGAEGFFTQPVFDLKLFDLCREWLQDEQVFWGLS
PVIGPRSRSYWETTNHVVFPKDFEPTLDANIQFAQSVLRQLSQDQGCAYLMPLRVKLDQY
LPPLMSALTA
>A0A5P8PZU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schleiferilactobacillus harbinensis|TrEMBL
MQINQLFKDRPVISFEVFPPRKNATAASLRKMDETLAVLSDLHPDYVSVTFGANGALQAT
GTLATASYIKDTYGIETVAHLPASQLSADQIHGLLNELQAHGIENILALRGDIPAGGRLS
NDFPHACDLIRYIHQCGDFNVIGACYPEGHPESPDLATDIHYLKDKVDAGASHLISQLFF
DNQVFYDFIAQARAAGITVPIQAGIMPVINAHQIERMATMSGVALPEKFTRMMARFQDNP
VAMREAGIAYAVDQIIDLLVHGVDGVHLYTMDNADVAQRIFAAAEQVIHA
>A0A370E269|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|endosymbiont of Lamellibrachia luymesi|TrEMBL
MTTNRSFSFELFPPKTEKGFENLKTAVNQLNALDPEFFSVTYGAGGSTQDRTFASVDWLR
EQQIETAPHLSCIGSSREEILQILDRYHEQKIRRLVALRGDLPSGAGLGSLGDLNYANEL
VEMIKERYGDHFHIEVAAYPEFHPQANSAKADLKNFKRKVEAGADGAITQYFYNPDAYFC
FVEECSDMGISIPIVPGIMPITNYVQLARFSDACGAEIPRWVRRRLESFGDDLEGIRAFG
AEVVTELCRRLLDGGAPGLHFYTMNQAAPTLKIWNNLGL
>D5QDW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataeibacter hansenii ATCC 23769|TrEMBL
MVSEERIGNLLSCSCDMPPPALSFEFVPPRTEPMEQRLWQCIRRLAPLSPCFASVTYGAG
GSTQASTYATVLRLRRETDLVPAAHLTCVGATREEVDAIARSYWEAGIRHIVALRGDPPA
GTADYTPHPGGYAYARDLVAGLRRIADFDISVAAYPETHPAALSPEADLDNLKSKLDAGA
TRAITQYFFDASTCLRFLDRCQSAGINAPIIPGIMPVSNYEQVARFSALCGVAVPAWLRR
LFEDTDENPELRRIVASIVAVEQIRTLQANGINEFHISTLNRADPTYAIAHILGLQEIGR
SILDHVADYPEQEETSDEREAETNSDTAGRTEEGASPFMLRTMFG
>A0A261QJB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillaceae bacterium SAS-127|TrEMBL
MSFLDRLKHEVLTADGAMGTLLYSYGIDFCYEELNVEKREVIEQIHLEYIKAGADVIQTN
SYGANAYKLARYGLEHRVQQLNKASMQIAKKAASPNGRFVLGTIGGIRGMRKNSVTLTEI
EAAIFEQADSLLSEQPDGLLFETYYDFDELTTVLKMVRRLTDLPLIAQVSMHEPGVLQNG
MALNQALHHLEGLGADVVGVNCRLGPHHTIQALEEVSLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGQAAVKLRNEGVRLIGGCCGTTPKHIEATKKALASLPPITEKKVKAKQPII
IKETTIPSLPRLHEKVKTERTIIVELDTPKQLDTNAYIEGAKALHETGIAAVTMADNSLA
SPRVSNLAIASLLKMNHHIRPLVHITCRDRNLIGLQSHLMGLHALGLHDVLAITGDPTKI
GDFPGATSVYDVSSLELIQLIKRMNEGISFSGKPFKQKANFSVAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVFTKEKIIEVHEATKHLPTPIFIGIMPLTSSRNAEFLHHEVPGI
KLSDETLKRMKACEGDREASAREGVNIAKELIDTAAELFNGIYLITPFLRYEMSLQLIEY
IQQLDGKTNERGISHVQPTSN
>A0A7K1X3G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apibacter sp. B3918|TrEMBL
MKVTEHISNAKGKTLFSFEILPPKKGEDLQNIFSNIDPLMEFNPPFIDVTYHREEYEYRE
LPNGLIQKIVTRKRPGTVGICAAIQQKYKVDAVPHLICGGFNKEETENILIDFNFLGIDN
ILVLRGDPIKSEGIFKPHSQGHSYANELVSQVQNMNSGKYLHEEYAHGATDFCIGIAGYP
EKHFESPNLDTDLNYLKQKIDAGADYIVTQLFYDNTKYFEFVKKCRNIGITVPIIPGIKP
VSIKKHLTILPNIFHIDMPQELVMAVEKCKVNKAVYEVGIEWTVSQCKELMKQGVPVLHF
YSMGRSENIRKIAKQLF
>A0A7K5WWV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hylia prasina|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIATALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6A5QGY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ampelomyces quisqualis|TrEMBL
MHISQKLAQARAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQTVYGLETCMHLTCTDMEKSKLDEALRDAYQSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVKYIRDQYGNHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGATF
IVTQMFYDTDIFLDWVNRVRTKGVDIPIIPGIMPIHTHAAFLRRAQWTRCNIPQHWIDAL
EPVKNDDVEVREVGRGLVADMCRRLIDAGITHLHFYTMNLAQATRMVLEELDLLPDVESP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPTSIKDLSDLFVRYMEGKLEALPWSEQPITGEASSIQQDLID
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVLVSPEYIAEIITRIDRNP
EFTYYAVNKDGDLRTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHSGASPSRYAIQDVVDTWYLLNIVHNDFHVTRGIFPIFEGLQVKDIDKPLHNPSVDL
PTPTETNGANGTLGTNDSNGETQEAHGEEKQNSGLLATAKAAVADVTNGMKGLVVSN
>A0A7S2EJM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trieres chinensis|TrEMBL
ERAIDLVRLIRDLHGDYFGVAVAGHPEGHPSSASPEEEMEHLRDKVDAGADLIVTQFFYD
PEVFLRYVRRCRSAGISCPILPGIMPIQSYSSFVRMTAFCGIKVPPEVTARLEPVKDDDE
AVKRIGWDIATEMCRRVLTAGEEEEGEG
>A0A6N3EDQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella ratti|TrEMBL
MVTSLREKHKAGQFTITVELDPPKSASANKTFKEAAQLLDKVDAINIADCPMAKLRMSPI
ALAHLIKYRAQIDTIFHLTCRDRNILGLQAELLGAAALGVNNILTLTGDEPSRGDHPDAK
PIFEVDSMGLLKIAHTLNKGFDLAGNELEVPTNFYIGTTGNPGADDLEEEKAKIIRKVEA
GANFIQTQPIYDLEKAKRFIEMVAPLGVPVMLGLIPLKSFKMATYLHTKVPGISLTEDIL
NRMEKGGKEAGLEIALETLLEIKKVAQGVHIMPLNDIQTVLYLIDHV
>A0A0W8IB42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serinicoccus chungangensis|TrEMBL
MSNRYPSASLEWLLERARLEILPTASVAEQVHAHVEPGRTVTVTASPAKGLEATLAVTEQ
LADRYHVVPHLAARMIQRDHLPGLVEHLQGLGVTEVFVPGGDAVPTETTFTNALDLLVEL
EQMGRPFERVGITGYPESHPGIDDDVIVQSMWDKRRYATDIVSNMTFDDEQVGQWLERVR
RRGIEHPVWVGVPGPVDPAKLLRMASMIGVGDSVRFLRKQRGVFARIALPGFSTTRFVRR
IAALAGTQRLNIGGLHLYSFNQIEKTEAWRREQLGAVARLRDRSVGP
>A0A076HHZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. KORDI-52|TrEMBL
MERDLRTALQRAIEAGDQVLTAEVMPPRGADPSHMLAMAASLQGRVHAVNVTDASRAVMR
MSSLASCKLLLEAGLEPVLQMACRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAGDQA
NARPVNEFESVKLLQQVDALNRGVDPVQGTLPDGATTLFAGCAADPQSRSWSGLQRRLQR
KQGAGARFVQTQMVMDPEALERFQRELAGPLDLPVLAGVFLLKSAKNARFINRVVPGACI
PDALIHRLECAENPAMEGVAIAAEQVKRYLGIVRGVHLMAIKSEERIPMILDRAGVSSLP
G
>A0A1F4B6E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_63_19|TrEMBL
MVEESTNTNNPPAERVPGALEQACKSGRFVVTAELSPPDSADPQDQLRRATAFRDMVDAV
NVTDGAGANCHMSSLAASSLLTAAGFDSVFQLACRDRNRIAMQGDILGAAALGVRNLLAV
TGDGVASGDHPQARPVFDLDSVSLLRIARGMRDRGEFASGRRLSVRPDLFLGATINPFAP
PFEERIINFAKKIAAGAQFVQTQYCFDLAMFETFMREVRSRGLNQRCHILAGVGPLPSLR
TARWMRAHVPGVHIPEQVLHRLEQAADQKREGVRICVELIRALRGIEGIAGVHIMAHRNE
HLVPDILRESGLTEERGESSAQRDAT
>A0A2A2XXY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spartobacteria bacterium AMD-G4|TrEMBL
MHILDILKPGKPTVSFEFFPPKTDESQQALYETIRDLETIHPNFVSVTYGAGGSTRNLTH
DLVLRLKTSTTLDPVPHLTCVGHTHEEIAAILERYATAGVSNILALRGDPPRDQPNYNHS
GDAFPQAVDLVRFIKNFSGHSDPRGFGIGVAGFPEGHPATPNRLLELDYLKAKADAGADY
ICTQLFFDNHDFYDFRERCELAGIHVPIIAGIMPVTSQSSMRRMAELAGGARFPARLVKS
LQRAGDSTEAFRQIGLHYATEQCADLLNHGVAGIHLYTLNQSTATREICQRLGIL
>A0A5S5DUU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum adriaticum|TrEMBL
MKVTEHIKKANGNTLFSFEILPPLKGQHIQSVFDNLDPLMEFKPPFIDVTYHREEYTYKE
QENGLLKKQVVKKRPGTVGICAAIQNKYQVDAVPHILCGGFTKEDTENFLIDLDFLGINN
VVALRGDAVKSETYFKAEKEGHKYASDLVNQIQDLNNGLYLDDALLNSSKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKKGADYIVTQMFFDNQKYFDFVEKCREEGITVPIIPGLK
PLSTKNQLNLIPHRFKVDLPDELIKEVVSCNDNKAVRQVGIEWCISQSKELIQKGIPVLH
YYSMGKSSNIKEIIKKVF
>A0A2V9IVA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MREPFLERLEKRPLISDGAMGTMLYSKGIPFSRCFDELNLSMPQLVKEVHLGYVKAGAEV
VETNTFGATSSRLKKFELGEQVREINLAGARLAREVAGDDLYVAGSVGPLGIPLEPLGPT
SLEEAREIFRQQIAALVEGGVDLIVIETMVDLQEARQALLAARDVAPLPLVVQMTIQDDG
STPTGALPEDFTRQLDGWGADVIGLNCSAGPAGILETLERMARVTAKKLSAQPNAGLPRT
VDGRSIYLCSPEYMASYARRFIEVGVRLVGGCCGTTPEHIKAIKAAVRSLRPQPARAAAD
VRSRPVEVMQPVPLERRSRLAGKLAAGEFPVLAEIVPPKGCDPTREVEGALYLRDQSVDA
VNISDGAGSTARMSAQTLAAIIQQRVSIEVLLQYSCFHRNVLGIQSDLLGAYALGLRNIL
AVTGQPPVLGTYPAATAVLDVDSIGLVNVLNNLNRGLDVGGNPMGTQTGFLIGVEVNPYA
LDVEEELRRFQFKVEAGANFAVTQPVFDAEHLARFLKRIKSAGIARIPILAGVYPLTSFR
NAEFLNNEVPGVSVPPAVMERMRKADTGDQARAEGVKVARELLGEIRHLVQGVQISAPFG
RYAMAVEVASVLREHAEAANDQPSVAGRRAEG
>A0A6L7P5T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRRSELAAFLRERPRVGDGALGTALYAGGIASRRSFEDLNRSDPDRVRAVHTAHLAAGAE
VISTNTFGANPWKLGRHGLASEVAKINAAGARVARSAVRPGSLVLGSVGPSGEVVGPFDE
EKAPEFAAGFREQIAALVESGVDAVLIETFTSLTEARLALSAAREVAPDIGVIVLMTFSE
QATTVFGVAADQAAGTLERDGADAVGSNCGVGPDTTLTALERMRNAVSLPLVAQPNAGIP
ERTEGRFLYPSSPDYVAHYAKRYLRLGVSLIGGCCGTGAEHIGAVAGVVRAASAGARADR
VRAPARPAAAAPAEEAPAEIPAVPVPERSGLARCLAEGRFAVSVEMDPPRGAEPGKFLAR
VGDLADAGIRFVNVADGPRATARMSAIAFAALLERSGEVETILHYQCRDRNLIGIQSDLL
GAHALGIRNLLAVTGDPPKLGDYPHATPVFDVDSIGLVRILRGLNHGLDLAGNPLGAALP
FHIGVGANPAAADLEGEMGKFERKVQAGAQYCLTQPVYETRLLERFVKDVRGYGIPVLAG
VLPLVSSRNAEFLHNEVPGMSVPQPVRERLAAAPTRQRAREVGVSVARDMVAAARDLVAG
VYVMPPFNRFDLAIRSVTGLV
>A0A7X4I0U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKRIPDIYAEKGAAGRPVVSIEFFPPKTPQGDESLFERVLPRLAEARPDFCSVTYGAGGG
GTRARTLSIVDRMQREHGLTAMAHVTCVSFTRVAMNGFLDEAAGLGIENILALRGDPPPG
EPDFVRPVGGFDYAYQLIDVLKARSDEFAIGCAGFPEGHPDCTEAREVDWRRLRDKVDHG
AEFILTQLFFDNADYFRMVDHLTGPLGVAVPITPGILPILSTKQVKRFTALCGATLPPAL
VADLDRLGDDDEAVTEFGIEFASRQCEALLAGGAPGLHLYGLNRSRSALAIVRNLGLAAS
GLPAVRSGTAG
>A0A7V9DQV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MALGGPDGEVLTAALAELTRDFSVEVTPREAPKVPPFGSVLNPGTRIYITFLANTPFEDT
LTLAARAVREGMRPVPHLAVRSIPDRATLTAMVAALVKIGVTEVLVIAGSVSSPAGEYAD
TMQVLASGVLPETGITRIGVAGHPEGAPDIGPTELAAAMAAKNAVAAEQGLELYIVTQFS
FAPEPIIEWEQEIRAAGNRLPIVIGLPGLTSPAKLLKFGLSCGIGPSLKVLRKQSGGVLK
LATSSVYHPDQTMLGLVRSRAADPASLIRGVHFFPFGSLQRTAEWAAQVASGQFVVETND
TLRVTA
>A0A7W0SM82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MSGTVRDRLAGGVPSFSFEFFPPKDPASEAVLWRSLRDLERLRPSFVSVTYGAGGTTREG
TVRVTERIATQTTMLPLAHLTAVNHSVAELRNVVGRFAAAGVRNILAIRGDPPGDPSAEW
IKHPDGIEFAAELVTMVRRAGEFCVGVAAFPYKHPRSVDIEGDARYFVQKVRAGADFAIT
QMFFDAEDYLRLRDRVSALGCEVPIIPGIMPVTSMGTIERAPKLSGAPFPAKLAETFEAI
AEDKDAVRAQGIGQASELCQRLLDEGAPGIHFITLNRSTATREIWANLRETSPVG
>A0A8G0PNK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma simmonsii|TrEMBL
MDKITEKIAALPPDGEYFSLEFFPPKTAMGFSNLRVRLQRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREIGLTTCLHLTCTNMSQALIDQALEDARALGIRNILALRGDPPRAEY
RDADEPDQAASEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPY
LVEKVQAGADFIMTQLFFDIEAYEKFETTLRNHPSGTFKTIPILPGLMPIQSYAMIKRTA
KLSHAKIPEETMARLNAVKGDDEKVKMVGVDIVSELIGQIREIKSRTPGPKGFHFYTLNL
EKSISFILERTKLIPDAAEDEEAVVDETVAAAAQLVVPKISVNGNVPPRSSSHARTGRRQ
SSVGSDPHNRVIVGRAATHPEWEATSTEAGIPAESVNTRANTLAISEGEGALGREATWDD
FPNGRFGDARSPAYGEIDGYGVSIHMSVTQAVRLWGHPKVAGDINDIFVRHIRGEISAIP
WSEEDLLPESSIIKSKLEAMNRKGWWTVASQPAVNGLPSTDSTFGWGPASGFVFQKSFVE
FFIPSADWKILYDKLTSAEVEEVVCFYASNAKGDFISSDASGGSGRAVMSASTNAVTWGV
FPGKEIVTPTIIEEVSFRAWSEEAFDIWAEWAKVYGRGSDSQKLLDEIKEDRWLVNIIHH
DYVDTEALWRLLIE
>A0A2V9TD91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MAGDLLARLKKSPVLCDGATGTLLYAKGIFINRCYDELNVSQPDLIRGLHHEYLQAGAEI
IETNTFGGNSFRLARHGMENRVREINLAGARLGREAAKSFDVWVAGSVGPLGIRIEPLGK
TSYEEARAAFREQIAALVEGGVDLLILETFGYLEELHQAILAAREVNPKIPLVAQVTIDE
DGNCLDGSTPETFTPRLEEWGVDVIGCNCSVGPVAMLEAIERVRAVTSLPLAAQPNAGIP
RSVEGRNIYLCSPEYMASYARKFVAAGVRMVGGCCGSTPEHIRVMKSALRASEARSKVVA
PSASGGVATPLPSPALPLDKRSTIGAKLAAGEFLIMVEIVPPKGTDIRKELEGARFLKSV
GVDGINIPDSPRASARMSNQALSLLVQQQIGIEAVLHYTCRDRNVLCIQSDLLGAAATGI
RNLICITGDPPKMGNYPDATAVFDVDAIGLVNIVQNLNRGLDIGGNPISVGTSFVIGVGA
NPGVPNLDEEIRRFEYKVEAGAEYAVTQPVFDLSLLETFLRQIEHCRIPVVAGIWPLVSV
RNAEFMKNELRVSVPNSILDRMAQAKTPEAAREEGIAIAREMLVAVHHMVQGAQISAPMG
RYASAVDVLEALGSSRPATA
>A0A2V9J325|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MLKPFLEHLDKAFVICDGAMGTQLYSKGVFLNRCFDELNLSRAPLVREVHQEYLWAGAEI
LETNTFGANRIKLEPHGLADRVRDINISGVQIAQEVAQGSAYVGGSIGPLGIRLEPYGKL
GVEEARRIFAEQIAALVEGGVDLLCLETFTDLREIEAAILAAKELCDLPVMAQLTLEEDG
NSLDGTPPETFGPHLEKLGADIVGINCGVGPQVMLESIERMARVVTRKIAAQPNAGKPRN
FEGRNLYLSSPEYMASYAKRFVRAGVRVVGGCCGTTPAHIRAIRAAVVAAKSGASRIVAV
PAAEPTAPVEVTPVEERSHLGRLILAKKNITVVEMLPPRGVDATSALEAARHLKDAGVDT
LRISEAPRASARMGAIALAVLLERDAGVEPILHYTCSNRRLLAMQSELLGAYAIGIRNLL
LSDGEPIRVGDYMDATAVFDVDSAGVTRLAWGLNQGRDLGGKPIGKPAGFYVGVTVNPLS
LSTDEEIRRLEQKVEAGAEFVITEPIFVPDLLEAFIRRTQHCPVPVIAGIRLLTTARDTE
FLANEVPGVSVPDHVLNRMRAAGTPEREREEGIAIARELVRSMRGIAQGIDLSIWNLPYD
SALEVLAGS
>A0A7V9IR62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MGRTIAARLRSGEPSFSFEFFPPRDAAAERQLWQALRELERLRPSFVSVTYGAGGTTREG
TVRVTERIATDTTMLPLAHLTAVNHSRAELRHVLGRFAAAGVHNVLTIRGDPPGDPQAEW
VKHPDGLAYAEDLVRLVKASGDFCVGVAAFPYKHPRSPDFASDAQYLVRKMRAGADFAIT
QMFFVVEDYLRLRDRVSALGCDVPIIPGIMPVTTMRTIERSAQLSGAPFPSKLRDRFESV
AEDPAAVRAMGIEQASELCQRLLREGAPGIHFITLNRSTATREIWSNLQARVGV
>A0A2V8ERI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKPFLDAIDDGVLVCDGAMGTMLYAKGVFINKSFDALNVTQPDLVAEVHQEYVRAGADIV
ETNTFGANRIKLGSFGLADRLYAINEQGAKIARHAADDRAYVAGAIGPLGIRIEPWGKTG
VDEAREYFREQAQALADGGVDLFILETFRDLNEIGAAIDAVRSVSDLPIVAQMSTEEDGN
TLDGTPPEKFAPELEKRGATIIGVNCAVGPAPMLDTIERMAAVTTRKLSAQPNAGQPRDV
EGRNIYLCSPDYMASYARRFIMHNVRLVGGCCGTTPEHIRQIKTAVRAMAPAVVRATDAA
AARPSIAAAIPRGIDSPPVAREHKSRLANALARGTFVAAVELLPPRGYQTDQAVEHARRL
KIGGVDVINIPDGQRAGARISALSLAVLIEQQAGIETVLHYACRDRNLLGIQSDLLGAHA
MGVRNLMLVTGDPGRVGDYPDATAVFDVDAIGLTNVVARLNRGCDVGGQSIGAPTAFHIG
VSVNPAASNLDQELRRFEYKVEAGAEFIVTRPIFDVPGFESFHRRIEGARLPIMAGIFPF
ESARNAEFMANEVPGVRVPDALLDRMRRADGEAATQEGIAIAREIATALRGAVQGVQIAT
QSGDIEAALAVLDGLR
>A0A7X8UBL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTQSNIERLLEKGVFVVTSECGPPKGADAEAVRKKGSLLKGVVDAVNVTDNQTSVVRMSS
FASCLILKEMGFDPILQMVCRDRNRIAIQSDILGAAAHGINNILCLSGDHQSFGDHPGGK
NVFDIDSMQLIQTVRTMRDEGRLIGGEEVKGRPNLFIGAAENPFADPFEIRAMRLGKKVK
AGCQFLQTQCIYNLEKFGKWMEMVRERGLHEKCAILAGVTPLKSAGMARYMKTSVPGMDV
PDELIDRLKGVPKEKQAEEGVKICVEMIQQLKEVPGVRGVHIMAIEWEEKVAEIAKAAGL
SPRPEA
>A0A7V0UDQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRDFLSSLQERALVCDGAMGTMLYEKGVFISRCFDELNLSNPDLVRAVHSDYVQAGADVI
ETNTFGANRTKLMTHGLAEQRRRINIEGARIAREAAGADVFVAGAVGPLGIRIEPWGKTG
VDEARALFREQAEALETGGVDFYILETFSDLNEVRAAIQGVRDVSNKPIAAQMTIEEDGN
SLEGTPPEIFARRLDEWGADVVGLNCSVGPQIMLDAVERIAGVTSKPLAVQPNAGKPRNV
EGRNIYLCSPEYMASFTKKFVQFGVRLVGGCCGTTPRHIKAMQGVVRSAQPALRTITVSR
PVADEPQVNAVPQAEKSRLARKLARGEFVKIVEMIPPRGHEYSEALERAKYLKAHDVDVI
DVPEAPRSSARMSALSLALLLEKTTDIESLVHYACGDRNLLGMQADLLGAYALGLHNLLL
LTGDPPKFGDYVDATAVYDVDSIGLTNMVRRLNAGVDVGGKSIGSPTGFLIGVGSNPSAD
DIEQELRRFRYKVEAGAEFTLTQPVFDVPALERFLGRIRDCSIPVIVSILPLASYKIALF
LHHEAPGCSVPGPILDRMHAADTPAAARAEGIRIAQEILDQVKGMVQGVQIRGPFEEYET
AIEVLSVVMGERRTA
>A0A7Y4WTR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSGLSVAVLTARDAGIEPVLQYSCRDRNLLGMQSDLLGAHALGVRNLVVVTGDVRGVGDY
PDATAVFDVDSIGLANVVSRLNHGLDIGGQEIGMPTAFLIGVMVNPGAEDLEAELRRFEY
KLDAGAEFVVTKPVFDVATFERLAKRLEASGVPVVAGLWPFESALNAEFMANEVPGVRVP
DEVVARMRTAEAAGGARAEGVTIAAEVGRALRAQVAGVLVATPSGEADDALAVLDGIG
>G6F2E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Commensalibacter intestini A911|TrEMBL
MTRISIELIPRDKQNLITDMQNIKEYFPVANTINIPDLMRFPLHSWEAFDITYPLYPNTI
PHVRAIDIDPNAPLPGYNQKNLKEVLVIQGDPPADLHKITYPNTTETILRRYQKELPHLT
LYAAFDPYRRSPKEELEHIQSKEAAGAKGFFTQPIFDEKLLEVCMDWLHDKNVFWGLSPV
VGPRSKSYWEVTNNVIFPQQFEPTLEANIAFAKRALNLIKQTNSNTYLMPLRVKLEKYLP
PLLEVFL
>A0A3N5GC35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MTVEHFRERAANTLSRLRSTPTVSFEFFPPKDEHMEQTLWQSVERLTPLRPRFVSVTYGA
DGSTRTRTHNIVTKIQSSTSLTAAPHLTCIGAPRQEILDVARNYWAHGIRHIVALRGDPP
QDSGRYAPHPDGFAYAVDLVHGLKSVADFEISVATYPEPHPESPSPDFELQNLKAKIDAG
ADRAITQFFFDPDVFLRFRDECARSGVSASIVPGILPITRFPQMLRMAQRCGASVPDWLV
HRFDGLDEDPDTRRMIAASVAIEQVQQLERHGVEEFHFYTLNRSELTFAICHALGVRPQG
DDRRLESGGSR
>A0A4P1RYI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
PIIPGIKPVTNRRQIEQIPRLFFATMPQELVKAVEGAKTPAEAFNGGTRYMAKLVQQLLD
FGVPGIHLFIQEKSDDSHALLSAVYGS
>A0A2V8XJ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
PKREGDRIVYPKSSPEYFALFAREAAALGVRILGGCCGTTPAHIRAMAEAVKSLRPAKAH
AVVHSVATMAKPASLSEREPESKFWKKLQAKQFALCVEIDPPKGLSLDRIFEQVGKVMAS
KKVDAIDINSGAMARVGMDALIVAGALEARGVETVPHLTTRDQNIIGLQAALLGAWTVGG
VRNILAITGDPPSVGDYPEISGVYEVDSVGLVKVLHRLNQGTDWAGKTLGGETNFTIGVA
LNPVADDLDNEIERFHAKVEAGAHFAMTQPLFDPEHWHAFLKKLGGKPSIPVCIGIWPLN
SYKQALRLNNEVPGIVIPERLLKSMEAAGASARDCGFKVARDMLAWSRTELAGAYLIPPF
KRYEEILEIL
>A0A5B6U7M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. SARCC-RB16n|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHQVDAVIQEFTDMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVA
GSAAA
>A0A2V8G3Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
GCDVGGQPIGPPTAYHVGVSINPGAPNLDEELRRFDYKVEAGAEFVVTRPVFDVRAFERL
LKRIESAKLPIVAGVFPFESARNAEFMANEVPGVHVPGALLDRMRKADGPEAGAAEGITI
AREIAAEVRSRVQGLQVSTASGNIDAALAVVDGLR
>A0A6B3SKN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noviherbaspirillum galbum|TrEMBL
MTLPNVSIEFFPPKTPEGVEKLRVARGKLAALQPKYFSVTFGAGGSTQKGTLETVLDIKG
EGHDAAPHLSCIGSSRDSLRAILQEYKENGIKRLVALRGDLPSGYGAFGEIRYANELVEF
IRAETGDWFHVEVAAYPETHPQARSPQDDLASFVRKVNAGADAAITQYFYNADAYFRFVD
DAARAGANVPIVAGVMPITNYSQLMRFSDMCGAEIPRWIRLKLASFGDDTASIKAFGLDV
VTALCERLISGGAPGLHFYTLNQAAATVEICRRLGG
>A0A087E5H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium subtile|TrEMBL
MHAPMFSLEVFPPKRNAPVGTIYDTLDGLQGVDPDFISVTYGHGSQSDRTATARIAHTIT
AEYRIPAVAHLTAQYLDEAQADATLDMFEQANVSAVLALRGDRNPDREPLGVFEHASDLA
AYIRRTRPGMTVFGACYPEGHPQAHDLDEDIRNLKIKVDAGATHLISQLFYDNQDFLRFL
DKARAAGINVPIEAGIMPVTNAGQVRRMVRTCSSRVPQRLETMLDKWGSDPTTLQDAGII
YASEQIADLVARDVEGIHLYTMNRPSVTRGIWRNVQPLFAKAASTAPVSAVSAAV
>A0A2E9NNP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSSTGSSSIHCIRDLHSAREPGDRPVISFEFFTPKTDAGDVKLMEVTMPALMALAPDYVS
VTYGAGGGTRAKTLTLVDAIQKQFDLTAMAHLTCVGHTRDEIAAILDEAKALGIRNILAL
RGDPPAGEAEFTTPDGGFEFSYQLVEFIRAHGDFCIGTAGFPEGHLACEGRKLADWGYLK
QKVDAGANFVLTQLFFDNADFFAFRDHMVRQLGVTVPICPGILPILSSKQITRFTHLCGA
RIPAALQTRLEDLADDDAGATAFGIEYATAQCEELIREGVRGLHLYSLNKAHSVAAILGN
LGLDHR
>A0A7Z8R0Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium HT5|TrEMBL
MTIKNKADLFSFEFYPPKTEQGDLNLEQVHRDLAKLNPDFFSVTFGAGGSTRDKTYDTVV
KIQKNGVSAAPHLSCVASTKENIREILANYREHGVSKIVALRGDLPSGMMSAGEFRFANE
LVDFIRAETGDHFQIHVAGYPEVHPQAGNATEDFNNFKRKVDAGADAVITQYFYNAEAYF
YFLDKCEKSGINIPIVPGIMPITNYAQLFRFSGMCGADIPRWMRKTLECFGDDKASIMAF
GEDVVSKLCQELLDNGAPGLHFYTMNQSKPTLAVWDNLSFA
>A0A7W7W1D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lipingzhangella halophila|TrEMBL
MFGSPSHTETEYDAAQRPRQIRDLLKTGEPTFSFEFFPPKTAEGRQKLWQVIRELEALSP
SFVSVTYGAGGGTRDHTVEITERMATDTTLLPVAHTTAVNHSVAELRHLIGRFADAGVSN
MLALRGDPPGDPLGEWVKHPEGLEYASELVELIKQSGDFSVGVAAFPFKHPRSASVDEDV
DFLLRKFRAGADFAITQMFFDAEDYLRLRDRVAAKGGDVPIIPELMPVVKYSTIEMSEKL
SGAPFPAHLAEEFERVKDDPKAVRELGMEQAQRMCERLLDEGAPGIHFITFNQSTATREL
YERVAGHRVPAMAGGRP
>A0A0B0IHR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus okhensis|TrEMBL
MSFLDQLAKKVLIGDGAMGTLLYEQGIDQCFEEVNVKNPEVIRKAHHQYVLAGADVIQSN
TYAANRLKLEKYGLDKEVRSINRSGVRLAKEAASGNTFVLGTVGGIRRFQLEEWSLSEIE
AAFTEQMDELLAEGVDGLLLETFYDLEEAKMAANLARKLTNLPIVANLSLGEVGVMNGGI
PVYKAFEQLTEVGADVVGLNCRTGPFHMLRSFETIQLPKKGFLSAYPNASLPDYRDGRVF
YQSNADYFQDMGEKFIKQGVRLLGGCCGTTPAHISAFVKVRDYTEPITSKTVKPLVGFMR
ESIEIPRKEKPLPEMVKERKSVIVELDPPKKLNTNRFMKGAKALKEAGVDAVTMADNSLA
SPRVDNLALGAMIKEQIGARPLVHITCRDRNLIGLQSHLMGLNALGIDDVLAITGDPTKI
GDFPGATSVYDVSSFQLISFIKQLNEGISFSGKELGQKANFSVGAAFNPNVRHLDKAVKR
MEKKIESGADYFMTQPIYSIEQIESLANETKHIKEPIYIGIMPLTGTRNAEFLHNEVPGI
KLTDDIRAAMAACGEDKIASATEGIQIARSLIDAALQYFNGIYLITPFMRYEMTVELTKY
IEARKPITQGSK
>D5GMM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tuber melanosporum (strain Mel28)|TrEMBL
MVHIAPKLVAEHKKNGRPTFSFEYFVPKTAQGVQNLYDRMDRMNQLGPQFIDITWNAGGR
LSNLTCEMVNVAQSVYGIETCMHLTCTGMPKSKVDNALKEAYKAGCTNILALRGDPPREN
EKWEADPHGFRYAKDLVKYIKSNYGNHFDIHVAGYPEGCDDGTDPELLLEHLKEKVDAGA
SSIITQMFYDVDIFLDWVRKCRDIGITVPIIPGIMPIHTYAAFMRRATWTKCHIPEKWLY
LLEPVKNDDVAVRDIGRDLMVELCQKIIDAGILHLHFYTMNLATATRMCLEGLGLIPSLQ
ERTKALPFRPSLGLNRKEENVRPIFWKNRHMSYVQRTQEWDEFPNGRWGDSRSPAFGELD
AYGIGLRGSNEANIKIYGYPKTIRDLGELIKQYLTGNLPSLPWSEGYINSEADTIRDELL
KLNERGFLTINSQPAVNGVKSTHPVYGWGPKNGYVYQKSYLELLVSPEHLAELITRIERD
PDLSYHAVDKNGTLKTNSSEGPNAVTWGVYPGKEIIQPTIVETISFLAWKDEAFRLGDDW
AKCYEADSASRHLIQEVMDTWFLLNIVDNDFYRSEKIYRLFDGMEVPNMDESLIDGLTSA
>A0A7X6GNP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium R_SAG5|TrEMBL
MTTPEISFEFFPPKNLEASFRLWDTVQSLAPLAPRFVSVTYGAGGTTRELTRDAVTTLHK
NSGLKVAAHLTCVSATRQETLDIADQYAAAGITDIVALRGDPPKEQGRFTPTEDGFGSSV
ELIEALAAKGKFNLRVGAYPESHPEAASQQANVEWLKRKLDAGADEALTQFFFEAESFFR
FRDACAKASIDTDRITPGILPIENWKGVRRFAEACGTTIPAWLDEAFEKAQRDDRCDLLA
TALCSELCTELLDGGVKKLHFYTLNRPELTRDVCHALGVKSKARLQNVA
>A0A0B6TI63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium marinum DSM 44953|TrEMBL
MNATAPQHSVKRRFSASVPLDSFDPVETHQAPVPSRTSLSFEVMPPRHDVDETKIDELLA
TLGSYRPDYISVTSSRNSGWLEGTARFIEKVDAQTRIPTLAHLACTAGTRQELIDWINRL
MDSGVRGFLALRGDYAEGQTGMPAGYLPHATDLISLIRSLENDQRARFGAGRLAIGVAAY
PSGHEESASRDEDIDVLLAKQRLGADFAITQLFFDAEDYLRFAERARLAGVRIPLIPGIM
PMTSLARLRRMGELSGLTVPDRLTRRLAAAGPEGEYQTGLDLTAELAQTILAAGAGGMHV
YTFNRPDTTTELLDRIGIAPRPTG
>A0A1N6DTL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurivirga caldicuralii|TrEMBL
MQSQQKYPQPLSLEFFPPRTDAGFEKLKGTIDALGALKPQYISVTYGAGGTTQARTVETV
EYIQTQTPHDAAPHLTCIGQTRESVLQLLHTYDQLGVNRIVALRGDLPSGMLDPGEFKYA
SDLVRFIREETGDRFTLEVAAYPETHPQAKNCDEGIKWFKYKVDQGADEAITQYFYNVDS
YLYFIDSCEQAGIDLPIVPGIMPITNYDQLIRFSSMCGAEVPRWLRCRLESFSDRGDMEG
LIAFGRDFVTTLCQRLLDAGAPGLHFYTMNQVEPTLSIARNLTIHHPA
>A0A318EG48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinimarinibacterium flocculans|TrEMBL
MTAQKIQFSFELFPPRTPAGWDKLPALASALAAVQPAFFSVTYGAGGSEQNGTYDTLIRV
VEQTGIETAPHLTCIGSTRARIGALLDQYRAAGVTRIVALRGDLPATAASSEAPGELRYA
SELVAFIRETHGDHFTLEVAAYPEMHPQAANPDADFDAFRRKIDAGADGAVTQYFFTAEA
YFDFVERCTRAGITVPIVPGIMPITNHAQLTRFSAACGADIPRWIRLRLEQYQDDKAALQ
DFGLEVVARLCRALLDNGAPGLHFYTLNQAEPTLRLWQHLGLPTPTGS
>A0A4U0YU68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopseudomonas bauzanensis|TrEMBL
MTTSKEIPVSFEFFPTKTEAGHEKLIAAAHVLADQQPEFFSVTYGAGGSTRDRTINTVLQ
LDQQVKVPTAPHLSCVGDSKADLRQLLTEYREAGIRRIVALRGDLPSGMGRASGELRYAN
ELVEFIREETGDHFIIEVAAYPEAHPQARNFEADLENFVRKAKAGADSAITQYFFNADCY
FHFVDQVRKAGVDLPIVPGIMPITNYTSLSRFSDACGAEIPRWIRKQLESYGDDSASIAA
FGTEVISDMCQRLLDGGAPSLHFYTLNQAQPSLAILDNL
>A0A1R4KRD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. JB197|TrEMBL
MALSLQEKIEDSNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQARPFPFRQTVDPREYSNLLRGLSHLDVITYKSVAQRSANEFKDWLSETKNDYDL
KNIVLVGSPSSIGDIKLSLPDAYKTLAEQSDDFFLGGVTIAERHSNKRNEHERLIEKTAQ
GCKFFISQAVYDAQATIELITSYARSCKAQGLEPKRLILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDAENTLSESVRICRENLDLILKSCAHLNVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKLIA
>A0A1J5AXI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium CG2_30_33_31|TrEMBL
MKVIDHIRQSKGTLFSFEILPPLKGEHFEQILQNIQDLLEFEPAFIDVTYHQQEVEYRDL
PNGNIEKRTVRKRPGTVGISAAVLFKTGIDVVPHLICGGFSQEETENALIDLHFLGINNI
MLLRGDPPSTVKYFKPEPDGHKNALGLVKQVNNLNNAIYLEKELQNTHSTDFCIGVAGYP
EKHSEAPNKQLDIKYLKQKVDAGAEYIVTQMFFDNKKYFDFVNDCREVGIKVPIIPGLKP
LVSINQLMNLPQTFHIDMPEALVNEAIKCKDNISVRQLGIEWAIAQAKELKKSGAPVIHF
YTMGKSDNIMKIAKEVF
>A0A0C3DK16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio mytili|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVQRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKTKTGLVAAPHLTCIDASREELINIADDYWNNGIENIVALRGD
IPPGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPGWMSRQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQSAV
>A0A7Z8Y5R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas mediterranea|TrEMBL
MMAASSTNLAEARALLLSPLGPVARAGSNHDAVRVSFEFFPPKTDEAEANLWTAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIIAETSLRPAAHLTCVEASRDEVDEVIAGYKSIG
VDHIVALRGDPPGGGGIGGVYQPRADGYANATELTAAISRVGGFDVTVGAYPEKHPESPS
IDHDIDVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLT
RMCGACGTSIPDWLKAHFDGLDDDPETRRLLAASVAAETCARLHEEGFSDFHFYTLNRAD
LVYAICRVLGVREQKAAA
>A0A7U5BGC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas hengshuiensis|TrEMBL
MAAPLFADVAGDIDISFEFFPPKSEKMEAALWESIETLGPLGPRFVSVTYGAGGTTRDRT
HATVARIARETGIPAAAHLTCVEATRDEVDAVAEAYWAAGVRHIVALRGDPPRAGEKYQT
HPGGYENAADLVAGLRRLHPFEISVSAYPECHPDSPSKQADLDNLKRKIDAGANRAITQF
FFEPETFLRFRDDAAAAGIDAEIVPGIMPVTNYAAIQRMAAMCGTEVPAWLGRLFDGLED
HPAARQLVAATLTAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGVRAKPGAVAAAA
>A0A8J4SU94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora kernoviae 00238/432|TrEMBL
MGKIIESIRSTYAATADDPTTRPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTDQLKRILKNARAAGIRNILALRGD
PPIGAERWAPVEGGLSNAMDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMVQWISDCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPTEVLTDLDAIKNDDAAVRRYGTQLAVETCRRLLKVGVHSLHFYTMNLATT
VTQVLEGLQLLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRIELWGTPQAEEDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAVIRDNLQWLNYNGFLTINSQPRVNGAPSSDPSVGWGGDDGVVFQKAYVEFFVS
PEKLTHLVKVMNRDYPQLSFHALNRQGEEHRNTPLHSVTAVTWGVFPGTEIVQPTVVDSD
SFAAWKDEAFELWQTQWASVYAEDSRSHEVIQHIYDTYFLVNIVDNDYANDESDIFSIFT
RIITQAMDKEQLRERVLDLETRREKMYDTLASFQSLQEELSGDLRAAHTEIASVRNENLE
LKDKVRQLQSQLALTSL
>A0A8H4K759|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium acutatum|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQQWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMIARIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>U2J8X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sobrinus W1703|TrEMBL
MEKGADMAQLLERLKNEILVADGAMGTLLYSNGLDNCYEAYNLSHPADIKKIHLAYIEAG
ADIIQTNTYGAKRHKLKNYGFDDQVKEINQAGARLAREAAGDKTFVLGTIGASRGIRQCD
LDLEEIVRETVEQAQFLLETGVLDGLLLETYYDAEELLAVVKALRPLTELPLITNLSLQE
VGLTGTGQSLVDIFSQLIMLGADVVGLNCHLGPYHMIQSFKQIPLFAQSYLAVYPNASLP
ALDTATDSTYQFSSNADYFGQSARLLAAEGARIIGGCCGTTPAHIRAVKRALGGLKPVQE
KYLTPLAKEADLLRQVKTGETLVDKVKREVTIVAELDPPKNLEIAKFKEGVKALDTSGVA
AITLSDNSLAHTRICNLSLASLLRDEISTPFLLHLTCRDHNMIGLQSRLLGMDLLGFDHI
LAVTGDPSKLGDFPGATSVYDVTSFKLIQLIKQLNQGKSYSGASLKKATSFTVAAAFNPN
VPNLARSGRLIEKKITSGADCFITQPIFEGETIKQLADLSESYEQPFFIGILPITSYNNA
LFLHNEVPGIKLSEAFLEKLARVKDDKSKCQEIALAESKKLIDQALTYFKGIYLITPFMQ
YDLVLQLVDYIKAKQ
>A0A6A6NK92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hevea brasiliensis|TrEMBL
MDRMVSHNPSFCDITWGAGGSTADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQ
TIKSNGIQNVLALRGDPPHGQDKFVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAH
PDMIGSDGVATPENYQKDLEYLKRKVDAGADLIITQLFYDTDIFLKFVNDCRQIGINCPI
VPGIMPINNYKGFLRMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMDFQCQNL
GLIDESKITRSLPWRRPTNVFRAKEDVRPIFWANRPKSYISRTLSWEQYPHGRWEDSCNP
SYGALTDYQFMRARARDKKLHDEWATPLNSIEDILEKFKKHCLGKLKSSPWSELDGLQPE
TKIINEQLGKINLKGFLTINSQPAVNGERSDSPSVGKLGGPGGYVYQKAYLEFFCSTDKL
QVLVDKCKSFPLITYMAVNKGGTLVSNVGTNDVNVVTWGVFPAKQIIQPTVVDPASFNVW
KDEAFEIWSRGWASLYPEDDPSRKLLEEVQSGYFLVSLVDNDYIHGDIFAVFADL
>B6WWM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio piger ATCC 29098|TrEMBL
MQIAQALRQTTKPFVSLEFFPPAAESHLPEFYETVERLRSIDPLFLSVTYGAGGGKQQNT
LNVTAELARRGFTVMAHLTCVGAEPQAISDFVGNLRAAGVHNVLALRGDAPRGVSDWDWN
KGHFHNARDLVHFLRSEHPDLGIGVAGYPAPHPDAATFAADRAYLAEKLRAGADFVITQL
FFDVREYESLVSSLRAAGLETPVIPGILPIQSFDSLRRVLSLCGANIPGKLYLELEAAHN
EGGVEAVREAGLRFAARQIRQLLDCGAPGIHLYSLNKSEMCLRLVEEAGL
>A0A133QMC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus simulans|TrEMBL
MGHLPGATNVYDVNSRGLTELAVRFNQGLNIDGGALKTKTNFNIAGAFNPNVRKMEAAVK
RLDKKVDCGMSYFITQPVYTVERIQEIAEKTAHLDTPFFIGIMPITSYRNATFLHNEVPG
ISLPDEILDQFEAVKDDKQKTKELSLRICRKLIDEVIKHFNGLYIITPFEQVDFSLELTH
YFKKQTAKNQEAII
>A0A1W2CFP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa malonica|TrEMBL
MSEAVAIDKQAVLKTESKLEKLYSLGHFVVTGELGPPQHSDGHELEHHAHELKDIVDGFN
LTDNQTAIVRLSSIAAGVHVLKGGGVPIIQMTCRDRNRIAMQSDLLGAYSLGIRDVLCLS
GDHQSFGNHPTSKNVYDVDSVQLIDMVRKMRDEKKLLSDAAIKTNEPRFFIGAVENPFGD
PFEFRAIRLEKKVNAGADFIQTQAIFDIEKFARFMEMVVARGIHERTKITAGILPVRSVK
ALQYMKKDVAGMEIPDSLIERMKKTEDPKKEGIQIAIEMCNELKKIPGVAGIHIMPVGWE
AALPEIVKGAGFLPRPKV
>Q0AEV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas eutropha (strain DSM 101675 / C91 / Nm57)|TrEMBL
MLSQKNFTPTFSFEFFPPQTPEGMEKLRATRIQLARFNPKFFSVTFGAGGSTRERTLETV
LEIQAEGSPVAPHLSCIGSTRDNIRSILEKYHSHNIRHIIALRGDLPSGMAQAGEFRYAN
ELVAFIRKEFGDTFWIEVAAYPEYHPQARSALEDFTNFRRKVEAGANAAITQFFYNVDAY
LHFVEMCEAANISVPIVPGIMPISKFSQLARFSDGCGAEIPRWIRKKLESFGDDIPSIQA
FGLDVVTALCARLLEAGAPGLHFYTLNSAVLPTKIWQRLGLTGH
>A0A097QWW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hafnia alvei FB1|TrEMBL
MSFFHANQREALNQSLAELHGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGGGKPDMYACDLVSLLKEVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEVHSPI
IA
>A0A3D0H1F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacteraceae bacterium|TrEMBL
MSLREKLASGEFVVLAEMEPPKGVDVSAMVAHAARVKNRVDAFVVPEMSNAVMRMSSLGG
CMVLAGKGLETVLQVCCRDRNRLALQADLLAAHALGIANIMAV
>D0WAM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria lactamica ATCC 23970|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A5M4BB15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga felis|TrEMBL
MKVTEHIAKAKGKTLFSFEIVPPKKGNNIEELYRNIEPLIEFKPPFIDVTTSREEYFYKE
HPNGLLEKKITRMRPGTVGICSAIKYKYGIDTVPHVLCGGFTKEETEYLLVDCFYLGINN
VMALRGDAMKEERYFQPTKNGHTYAVELVKQIKDLSKGKYLHDVIETDYGADFCIGVAGY
PEKHIEAPSMSFDLARLKEKVNAGADYIVTQMFFDNQKYFDFVEKVRLAGIDVPIIPGIK
PITTKRHISLLPQVFKLDLPEELVSELEKCKTNSEVKQVGIEWAIQQSKELKNYGVPTLH
YYSMGKSDGIVDIVSKVF
>M3K3T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida maltosa (strain Xu316)|TrEMBL
MATVSERILSLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMVAFNPLFITVTWGAGGSTS
EKSLDLAATIQNEIGVTTVLHLTCTNTNKEIIDQALSRAKSNGIKNILALRGDPPRTEEY
WTPNCDFNAAVDLVKYIREKYGGYFCIGVAAYPEGHVDGSDSSKQDPKKDIPFLIEKVKA
GADFIITQLFYDVDKFIDFEKLLQQHTELKNIPLIPGLMPITTYKVFNRAAKLSHATIPK
TILDKFDAISTDDDAVKVLGVDVLRNIIDKIDKSTKIKGYHFYTLNLEKAVASILDKSDV
LRPVLEGPSHGIEHEDAICSDSDEDDIPDEQPVSKKHRQSSINDNDLTASRTLVGKALLN
DKKVLVEISTGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPNLKIHSPAEAASKWG
NPETIKDLTKIFIEHLSGKIDVLPWNDNPLSPETALIQEELFELNEKGWFSVASQPAVNG
CKSIDNIFGWGPRNGVIYQKSFVELFMPKKDWDQLLARINTLDSITYYVGDNTGKIEANI
PIGHDVKLSKNAITWGVFPQKEVVQPTVIDYESFKAWNEEAFLLWLEWSRCYKKTSKSFE
LLKSIHDDYVLVCLIHHDFPEEHALWDFLLDE
>A0A1Z5IUA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Secundilactobacillus pentosiphilus|TrEMBL
MKVVDCFKERPVISFEIFPPRPSASEKAIERFYDNLDVLASLKPAYISVTYGAGGSGKNS
GTLDLCRYIKKTYGIEAVPHIPGIHFTKAAVKAYLAELKAADIDNILALRGDLPQDGVIK
GDFQYASDLVSEIKRDGDFNVLGACYPDVHPEAKDSVEDIKNLKCKVDAGVSQLITQLFF
ENEHYYRFLERCELADINVPVQAGIMSVVNERQIKRMATMNGVGLPQKFLKMMNHYQDNP
VAMRDAGTAYAIDQIVDLLSEGVDGVHLYTMDNPVVTKRICGAIETLI
>C0QKT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforapulum autotrophicum (strain ATCC 43914 / DSM 3382 / VKM B-1955 / HRM2)|TrEMBL
MQFRKRLKTGEFARLVQIDPPKGTDVITMVNNAIKVKGVVDAFLVSEMKSAVMRMTSLGA
SLVLQQKGLDTIVQLSCRDRNRLALQGDLLAASALGIAAAMVVEGDPPATGDHVDAKAVY
DLTDEALVKAIASLSKGRDLAGVELAGSVDLPMGVELSTGLRGGEREKELDRMKRMIDLG
VCFFVTQPLFEFSMTEPFLKIAVKNGVTIIPTVLLVKSLGMARYMARNLAHIIMPEHVID
TLQKTPDKVKASISLAVDMIHEVREMGFGGVNVSCLGWEDKLPEVLGVMKGLKG
>A0A3M4LNQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. mori|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>T1Y6G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus CN1|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A7L9SKX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. infantis|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A7C9INI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solidesulfovibrio aerotolerans|TrEMBL
MRIRELMEAKRPFVSLEFFPPKEREAWEGFFGVVEQLLPVRPLFVSVTYGAGGSTHAHTL
EIVSRLKTAYGLEPMAHLTCVGASRDKIRGFLDALRAAGVDNVLALRGDPPKGQEHFVPD
SEDFQHASDLVTFIRQEYPQLCVGVAGYPECHPEAASPETDLTHLCGKLERGGNFVVTQL
FFDNDKYFAFVDKAKAAGITVPIVPGVLPVLSLASIKRFATLCGASLPPAYMAELEAADA
AGGSAAVAEVGIAYARKQAQDLIARGAPGVHLYTLNKAEAVLSIVSGLDY
>A0A1F4RD50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium RBG_16_48_16|TrEMBL
MGTELYTRGIFVNHCFDELNLKNPALVKDIHKGYIDARADIIETNTFGANKFKLKKYGVE
DKVFEINKRGAELAREVAGDRVFVAGSIGPLGILLEPFGKLSAEEAKKAVRQQAEGLLEG
KIDLFILETFGDLNELALAVKTLKEMSDLPVIAQSTFGDNRKTLLGHEPEDVVNVLKEVG
ADVIGVNCSVGPQPMLEVIGRMAKAGARLLSAQPNAGNPRVVENRVLYMSTPEYHAEFAK
RFITAGVRIVGGCCGTSAEHIKAIVNAVRALQPQRKGVSVRITPAKEIEVDVIPREEKSR
FASRLGRKFAISVEVLSPRGVDPAAVIDGVRRLADFGVDVINIPDGPRASSRMSPMALAQ
LIEKNVAIETILHYCCRDRNLLGMQSDLLGAYALGLRNILVVTGDPPKLGDYPDATAVFD
VDAIGLTRIVRNLNHGFDVAGKAIGTPTGWHIGVGANPGAIDLGLEIDRLYQKVEGGAEY
ILTQPIFDPDQLDAFLQRIKDVAIPILAGIMPLMSYRTVEFLNNEVPGITVPEWIGKQLA
EATDADAAKEIGIHIAQQAILKTKKFDKIKGIYLMPPFTKDKYGIAMEVLQVIC
>A0A0M1P210|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus solani|TrEMBL
MKPSLRQALENQVLVGDGAMGTYLYQKGFPVGISYEELNLTSPEVIGNVHRQYVEAGAQV
IETNTFSANYDKLSKYGLETKVGEINRAGVRIAREAAGDRGYVVGAVGSIRAGKRSNIST
SELKRYFEEQLSELISEGVDGILLETFYDVDEMQLALAQARMLSDLPVICQFAVEDVART
LDGFSMPDAYRILSHEGADVIGFNCRTGPNGIMRALETLNGIMNLPASVYPNAGIADYVD
GEIRYGASPEYFGKTALEFADRGARIIGGCCGTTPEHIAEIASSLSNYTPSPLPNVDEAE
INRIVVHETAEEQFYERSGEPTIVDIVKERHTVIVELDPPRDLDIGKFMKGAEALKKAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLIHIACRDRNLIGTQSHMMGFDALDIDH
VLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNEGIAFSGKPLKQKAKFVVGAAFNP
NVKHLDKAVARLEKKIASGADYVMTQPVYDPELMVRLREATAHLDIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDDVRSRMAGLEGEAGRAMGVKIGKELLDVATEHFNGIYLITPFMFY
EMSVQLMEYVWDKSGRRLTPLFH
>A0A7Y9A616|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium beijerinckii|TrEMBL
MIKELLKNDILICDGAMGTYYSEVTGNDVSYCEFGNLNDKETIKRIHKEYIEAGAKLIRT
NTFSANTYDLGVSLETLMDIIKSGINLAKEVTRNTSVLIGASIGPIKTDNLDEFSNEVLE
EYKYIVDCFLKNGIDIFIFETFSNYNCLKKISEYIKYKNIDSFILTQFAVKPDGFTRDGL
SAAKLIKEVRNTKYIDAFGFNCGSGPAHILEMVKKINIENEIVSVLPNAGYPEIIHERTV
YPNNPVYFAKKVNEIRSFGVSIIGGCCGTNPSYIKQLTQIVNENSKVVNANAKAEPKVKS
FEKKAKNTFKDKLENGEFVVAIELSAPIDTDISRIIDGAKICKENNIDLVTVPDSPMSKV
RADSTIISSKIKREIGIEAMPHVCCRDKNTNAIRSSLIGSHIENIRNILAITGDPISDAS
KVETKSVFNLNSFRLIELIESMNEEIFKEDSIYVGGALNLNVLNKEVEYNRMMKKIEKGA
KFFLTQPIYDDNAIEFLKMIKERTNVKILAGLLPVVSYRNAMFLNNELPGVTIPDKYVQM
FSENMSKEEAQEIGVKITVEIGKKLKGIADGLYFITPFNRVNMLIEIIKQINA
>A0A1S8R9V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium beijerinckii|TrEMBL
MIKELLKNDILICDGAMGTYYSEVTGNDVSYCEFGNLNDKETIKRIHKEYIEAGAKLIRT
NTFSANTYDLGVSLETLMDIIKSGINLAKEVTRNTSVLIGASIGPIKTDNLDEFSNEVLE
EYKYIVDCFLKNGIDIFIFETFSNYNYLKKISEYIKYKNIDSFILTQFAVKPDGFTRDGI
SAAKLIKEVRNTKYIDAFGFNCGSGPAHILEMVKKINIENEIVSVLPNAGYPEIIHERTV
YPNNPVYFAKKVSEIRSFGVSIIGGCCGTNPSYIKQLTKIINENSKVINANTKAEPKIKS
FEKKAKNTFKDKLENGEFVVAIELSAPIDTDISRIIDGAKICKENNIDLVTVPDSPMSKV
RADSTIISSKIKREIGIEAMPHVCCRDKNTNAIRSSLIGSHIENIRNILAITGDPISDAS
KVETKSVFNLNSFRLIELIESMNEEIFKEDSIYVGGALNLNVLNKEVEYNRMMKKIEKGA
KFFLTQPIYDDNAIEFLKMIKERTNVKILAGLLPVVSYRNAMFLNNELPGVTIPDKYVQM
FSENMSKEEAQEIGVKITVEIGKKLKGIADGLYFITPFNRVNMLIEIIKQINA
>A0A803P0L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cannabis sativa|TrEMBL
MERMVAHNPAFCDITWGAGGSTADLTLDIANRMQNTVCVESMMHLTCTNMPLDKIDHALS
TIKSNGLQNVLALRGDPPHGQDKFVQIQGGFACALDLVKHIRAKYGDYFGITVAGYPEAH
PDAIGPDGLASPEAYQVDLAYLKSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPI
VPGIMPINNYKGFIRMTGFCKTRIPSEVTAALEPIKDNDEAVRAYGIHLGTEMCKKILGS
GIKTLHLYTLNMEKSALAILTNLGLIEERKISRPLPWRRPANVFRVKEDVRPIFWANRPK
SYISRTTGWDQYPQGRWGDSRNPAYGALTDYQFMRPRSRDKKLVEEWSIPLKSVEDIHEQ
FKKLCLGKLKSSPWSELDGLQPETKIINEQLVKINGKGFLTVNSQPAVNGERSDSPVVGW
GGPGGYVYQKAYLEFFCTKDLLDALVEKCSRGFSSFTYMAVNKQGHWLANVDQTFVNAVT
WGVFPGKEIIQPTVVDPASFTVWKDEAFEIWSRGWARLYPEVDPSRKVLEEVENSYFLVS
LVDNDYIHGDLFAVFNEF
>A0A1Y1XWP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Basidiobolus meristosporus CBS 931.73|TrEMBL
MKVTSRIQQALEEKRPFWSFEYFPPKTDEGVENLFERIQRMSGLNPEFIDVTWGAGGSTS
DRTLEICTTAQAYQNLETCMHLTCTNMTKSKIDFALKEAKAAGIQNILALRGDPPRNHEY
ANECETQFRYAFDLVSYIRQEHGDYFCIGVAGYPEGQPESESKEKDLEYLKLKVDAGSDF
VMSQIFFDPQLFLRFVEDCRAIGITVPILPGIMPIQTYTSFRRLTNLCQIEVPTQILETL
ESIKHDDQAVKEYGVKLCIEMIQELRKGGVNGFHFCTLNLERSVRLILEGCGFVSKQLTK
IDGLPKQANGHTAPIQPTVLEGIIMQNESWDEFPNGRWGDSRSPAYGEMDGYGASLKVTM
QEAIALWGYPVDNDDISALFSKYIQGQLKALPWSDEPLFAETNAIGEKLADLNSKGYWTV
GSQPAVNGVRSNDPVFGWGPKNGYIYQKAFLEFFTSPEKLAELLAKAASNPFITFYAQNT
KGDFKTNVELEEPNAVTWGVFPSREIAQPTVIERGSFEAWAEEAFQIWNEWKMIYPPQSP
SAKLIQEIGDTYYLVNIVHNDFQNADAIFALFQ
>A0A4Y6S133|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labrenzia sp. PHM005|TrEMBL
MTETCLLANGRLPASTEMSPKQVVEKSELLAGIPSGTQVYVTDLGNASEDMIVSAAKILT
DKGLAAVPHMAARRYASAQDFERRITRLTQEAGVNDVLVIAGEADKAGPLTSSVALLETG
LFDKLGIKKIGVAGHPEGAPDIKPDVIKSFLMHKHELAKNSDAEFRIVTQFGFDPHQVSV
WLDEIRAWGNTFPVHIGVAGPAKMTTLLKYAAFAGVENSLNFLKKRGGAVVSMLSGYDPN
TMVEPLEARITSQPDSQLAQIHVYPFGGVAKTSEWLLARGSWSFQTPSSPLTANEIA
>A0A1Q6MG47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. CAG:131_42_139|TrEMBL
MKIRDLITQDKATLSFEVFPPKKDTDFADVEAAALGIAAFKPDYMSVTYGAGGSTKGHTI
QLAQEIQEKYDVPTIAHLTCVCASKEGIKTALADMKNAGIENILALRGDIPKNYDGQVFA
EFSHASELVELIKETGDFSVGGACYPEVHPDSANKHEDIIGLKKKVDAGCDYLTTQMFFD
NNIFFNFMYRIREAGISVPIIPGIMPITRRVQVKNAVKLSGCNVPERFKSIVDAFGDTEA
AMRQAGIAYATDQIIDLMANGVKHIHVYSMNKPEVAAGIQKNLSEILKI
>A0A1T4WHC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paucidesulfovibrio gracilis DSM 16080|TrEMBL
MRIPELMERRRPFLSLEFFPPKEREAWPQFFDVAERLKELDPLFVSVTYGAGGGTQDNTL
EIVRRLKRDMDMEPMAHLTCVGASAAKIEAFLEELRRADVHNVLALRGDPPKNNPDFDFS
SGEFRHASDLASFIKERFPEMAVAVTGYPEPHVESPSIPEDLHWTKVKVQAGGDFLVTQL
FFDNRLYFDFVERLRGMEVHAPVIPGVLPILSINSAKFILSLCGASIPGKFLSALESAHA
EGGDEAVREVGLEYAVRQAQELIDNGAPGVHLYTLNKAEACLEIGSKLKI
>A0A4Q4PMZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria tenuissima|TrEMBL
MERITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCIGVAAYPEGHSDQSHPQCQDPQFDL
PSLIEKTKAGADFIMTQLFYDVEAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTTLSHAKLPSDMLARLDAVKSDDELVKQEGVKIMDEMVEHIKARPDTCRRGFHFYTLNL
EKAVSHIVEDTHLIPSTIDDNDDVIVETTPAINLEPPPNGFVPHRRRSSAVNSGPRNRVI
ISHSSAAKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKDDISKLFRRHIEGDLEAIPWSEQSLSP
ETLTISKQLLALNAKGWWTVASQPAVNGVKSTDPVFGWGPKNGYVFQKPFVEFFIPASEF
AALKPKLDAHEQVTYFAGNAAGEFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIFQEWQRIYPPRSASSTLLGALRRDYWLVNVIWGDFVQGEGLWEFLEQ
>F2PS11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton equinum (strain ATCC MYA-4606 / CBS 127.97)|TrEMBL
MEKISDKINALPKDAHYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEETKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFNYAVDLVKYIRKKYGDYFCIGVTGYPEGHADESHPEVQDPLKDLPYL
IEKTQAGADFIMTQLTYDIEAYKKYEALLRNHESGTFKNIPIIPGLMPIQSYHTLTRVTK
LSHAKIPPQILAKVEACKADDEAVKRVGVDIVSDLVESIKKIATPGHRGFHFYTLNLEKS
VSFILERCNLIPPSSEAPSDSELEFESAVYAASGASNGVATPDGRSTNVNRLRASSMNSQ
PHNRVIVDRLTRASDRSERSSTVHETSAQTAGYPALNPPNRNTALQISEGLGSLGREATW
DDFPNGRWGDARSPAFGEIDGYGPSLHVTAQVARKLWGTPTCRDDISNIFKRLLSGELHA
VPWSEGGAGEEGGLNPETATIKAELLKLVEGRGWWTLASQPAVNGVRNDHPVFGWGPRGE
GFVFQKAFVEFFCSGDDFHSKLKPLLQSYGHDEFAWFATNAKGDFQSSTSPETPTQPPTD
PTEVPFDADPLTEMDNGSVNAVTWGVFRGKEIVTPTIIEAVSFRAWGEEAFGIWEEWRRV
FPRGSPSEKLIREIKDDVWLVCVVGQRFGAGGDVGKESNEEDGKLLWKVLAGEQTK
>A0A2N1T1R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetae bacterium HGW-Spirochaetae-10|TrEMBL
RSTGLDFCLGAAAYPEVHGEAPSAAEDLRNLKRKVDAGADFLVTQLFFDNEKYFSFVDQV
RAAGIEVPVVPGIMPITAFKQIERFTAMAGCAIPEFLVKSLAGVQDDAEALLNLSLEFTL
RQCEELLSKGAPGIHFYTLNQSRATAIILDRLRRSVSAERR
>A0A1Z8VPH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium TMED60|TrEMBL
MSKGESIGKILEKRKKLFSVEFFPPKDDAGGERMLKTAERFQPYDPDFVSITYGAGGGTR
VTTMRYAKLLQEEHGFEVMPHLTCVGHTRDELLTILEDFATAGFCNIMALRGDPPKGETQ
FRPIEGGFSYASDLVSLIRENFPHFGIGVGGYPEKHPEASDQATDLKNLKTKVDAGADFI
TTQLFFDNQAFFKFVSDCXKAGISIPILPGLLPALSLGQVKRFCSMCEARLPRELEHNLQ
QSEESDQPEIGADWALDQVKELLXGGCPGFHLYALNKSKSTLKILEGLGRKQS
>A0A0N8QE75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. aesculi|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A561U7I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora dendranthemae|TrEMBL
MSAALASALRNASYEVLPFRGTEDAVLTHVPADVPLTVTTTEARGLEPTLDLAVRLSKNG
YTAAPHLAARLVRDRTELGEIASRLLESGVDRLFLVGGDAAEPVGEFPDAESVLLALAED
GCEFGHVGIAGYPEGHSSIPDEVISEALRRKAGHADEIVTQLCFNPGTTAGWAARLHESG
ITTPIRVGVPGSVNRQKLIRVSAGLGLGQSARFLAKQSAMFWRFFLPSGYRPDKLVTSLA
EQIPLPGNNISGFHLFTFNDLAGTERWRQHQLSRLR
>A0A849AZ32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 5378|TrEMBL
MTKRVPISFEFFPTKTDVGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFQIEVAAYPEMHPQAENFDKDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVIDLGLA
>A0A7I0E882|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT4-31|TrEMBL
MTATPTTPPADPDCRSSIPFSFELYPPKTDAATTALHATIDALAAARPKFISVTYGASGS
SRTSSLDVLRYIRRATIVDPMAHLTCVGSSHAEASSLIREFLDAGVSSFLALRGDPPEGL
TENDAFLGDLHSAGELVQLIHRVQAERVPYQETPIPGLPRARAVKTEREHVRIAVAAFPN
GHPRSRSTAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPV
TSPGRLRRILELSGEELPAELSIQLEVEPTLEGQREIGISHAAALAEKLIAGGAPGLHLY
AFNQHETVLAVLDRAGALAPAQPVVSAHNPPPTHPSTSPADTRAGIHSTKDHY
>A0A843T4F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonas sp|TrEMBL
MPDFRELLADGRPHVFDGAMGTMLYSRGVYINRCYDELNLREPDLVRDIHRSYVRSGAEV
VETNSYGANRIKLSRYGLESELEAINARAAEIARSAAGDHVYVAGAIGPLGVRIEPYGPT
SVDEAYEYFREQAEGLLVGGVDLFVLETFSDLLEIQQAVRALRSLGVLPIVAQIVIQEDG
HTPLGTDASTFAEKLGEWGADVVGMNCSVGPHAMLESVDRLASATDRPLSAQPNAGLPRQ
VDGRTMYMASPEYMAEYAARMIRKGVRFVGGCCGTTPAHIKRIAGAVRQAVPGAVRPVVT
ETDEPQAAVPTVPLAERSHWGRKLAAGEFLTTVEIVPPRGVDPTKMLEGVRLLKEAGIDG
VNVPDGPRAQSRMGVLATSLLIQQEVGIEPVIHYCCRDRNLLGMLSDLLGAQALGLRNLL
LITGDPPKMGPYPDATAVFDIDAIGLTNLAARLNRGLDPGGSAIGEATSFVLGVGVNPGA
ADLEHELRRFYWKVEAGAEYAITQPVFDLQQLFCFLDRIEREGIRIPIIAGIWPLVSARN
AEFLANEVPGVVVPDDVVERMLRASARGKEEAVEEGIAIAQQMLQEALPAIQGVQVSAPF
GRVPLALRVFEVLPERSQSANLQAAG
>A0A1J4TRA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacteraceae bacterium CG1_02_36_14|TrEMBL
MFNKLLDKLKHGTFISLETTPGHSPLFSPTIEKIASLELDKYVDAFSTTDNPLAKLKYNS
LFAAKMLQDRFNKPVIATMSMRDRNKIALQSDLLGANEVDIRTILALTGDPATISDQPHT
KGVFEADSSMLLDIIACFNSGIDYAGKPLTHKPQEIFPFAVVNAYSKNPKTLQKKMQKKI
KHGACGIITQPVYDLENAKRLLELKEAANKECSSEGREAELILGIFPITKLRTAQFLATH
VPGINVPNSWIEALRSANEKGSEEEYKVGLELSKNLFDEIKDLHPKIHLMTANQFQIAKD
ILV
>A0A0Q5GQR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. Leaf131|TrEMBL
MMSPQTPSRASTITDAYSLEVGANDIAELTAAAPRIMRGSTIAIPYLPSQDNGARLAAAQ
RVRALGFAPMPHLSARRIASLDELHTFVRRAVDEAGVERCLVIAGDAPSAIGPFSDSVSL
IDTGVFERSGIKTIGVAGHPEGHPNMRAAEQWDVLQRKCRSIAEHGMAPLIVTQFVFDAD
IVLAWLDALRARGIESPVRVGVPGPASVAVLARYAARCGVGACASMLSKYGISIGKLFSS
AGPDRFVDRLATGLTQAHGDVSLHVFPFGGIAQSVAWVEQYRSRTAVHISPSAS
>A0A1V5HEH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium ADurb.BinA184|TrEMBL
MSDIPYRANSNLERVLVAGHFGVTAELGPPKSAEVEVIHKKAEHLRGKVDAVNLTDNQTA
IVRISSIAAGKVLVDLGLEPVIQMTCRDRNRLAQQADLLGAYVLGIRNVTCLTGDHQVFG
NHPTARHVFDLDSIQLIECVRRMRDDGVFLCGDPIQNSKKSPVVAPKLYIGAAENPFGDP
FEFRAIRLAKKVNAGADYIQTQCIYDLERFERWMSQVCARGLHKRVKILAGLTPLRSFKM
ASYMATGVAGIQVPRELLGRMEAAKDGAEEGIRICVEQIQRLRQIEGVAGIHLMAIEWEQ
KVPEILERAGLLPRPVVPPAA
>A0A2U0H5C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Gd 4-13|TrEMBL
MTGKDIPGLQEAQSTIPAGTKINVTFLGNEDLEMRVAASKAVVDMGFVPVPHISARRLSS
QARLEEYLDRLQQVGASSNVFSVGGDPAEPEGPYPDSLSVIRTGLLQKYGATEVSIAGYP
EGHPDIPNDVLWKHLEDKSAALKEQGLDAVILTQFAFDTDPVTAWVNGVRERGIASEIRI
GTPGPAGIKRLIGFARRFGVGANAMIVKKYGFSLTNLMGTAGPDTFVTDLAAELAQNPAS
GDVKLHFYTFGGLKATSEWARDYIAARV
>A0A4Q4WRU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus sp. mg162|TrEMBL
MEKITDKIAALPADSNYFSLEFFPPKTAMGFANLRDRLDRMARALRPLFVNVTWGAGGST
AAKSLELAEICQRELSLTTCLHLTCTNMSRRMIDTALEDAKALGIRNILALRGDPPRAAE
YQDPNGEPEDAIDENFKWAIDLVRYIRKTHGDYFCIGVAAYPEGHADESHPRGQSLEHDL
PYLVEKTLAGADFIMTQLFFDVEAYERFERILREHPSGAFKTLPIIPGLMPIQSYQMIKR
TTKLSHAKIPDPISARLDAVKKDDEKVKNVGVDILSEIVERVKEIKSRTPGPKGFHFYTL
NLEKAVSFILERTKLIPPSTPEEDEAVADGLASGAPKLEINGSTHEPPMPTKHRQRRESI
ARSDVDASIRELPVPARDRLRRQSTVGSEPRNRVIVSEGSPSLPEYEATQAEASILAEPI
NTRANTLAISEGEGTLGREATWDDFPNGRWGDARSPAYGEIDGYGPSLHVTNAQAITLWG
YPKKREDINDLFVRHLKGGLSAIPWSEEEFNAETATITNQLLALNSKGWWTVASQPAVNG
LPSSDPTFGWGPQQGFVFQKAFVEFFLPSAEWRVLLEKLQSAEVQGTVCWYAANAAGDFV
SSDLTGGLAGEAANEPSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSDEAFGIFAEWAKVY
DKGSESAALLEAVRADVWLVNIIHHDYVDADALWNLLLN
>A0A1T4NUR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium ruminantium|TrEMBL
MIECNGKNIEFSCEVFPPKRNEDMYDIYKTLDEIKLLNPDFISVTYGAGGSNSKRTAQIA
TYIQNISEVEALAHVTAVGVNPEKLACMLEEFERKNVRRILALRGDKPRDMSDEDFKERY
YKYASDIIKVIKDNGNFKIAAACYPEKHPEASTVAEDIKYLKEKVEIGADELITQMFFDN
NKFYDFMDKLGAANVNVPVHAGIMPITAANQLGTSVALSGSSVPTELSNIIAKYSEDPIS
MRKAGVEYAIRQTEDLIKNGVDGIHIYCMNKFDVTREIYEAVVYDLT
>A0A3R6R6X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF24-2LB|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPELCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A653M2S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. 8AJ|TrEMBL
MATRIMPAPNRAASLELINNFSLEMTGKDIPALIEAKDRIPPGTRINVTFLGNEDLEMRV
AAAKAARDLGFIPVPHVSARRLASKGELEKFLQRLAEVGAAEHLFVVGGDPAEPEGPYED
SLALVNTGLLQQFGVREVGIGGYPEGHPDIRKEDLWRALEDKTAALAAQDLGASIITQFA
FDTEPVAAWIAEVRARGIQAPIRVGTPGPAGVKRLLGFARRFGVGANAMIVKKYGFSLTN
LMGDAGPDRFVNDLAAVLADRAPGQDQHLPGQVGLHFYTFGGLLATANWVRHFTAEEG
>A0A243PAY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. GW456-12-10-14-TSB1|TrEMBL
MTLNDPAAPLYADLAGDCHVSFEFFPPKTEKMEAQLWSAIETLTPLQPKFVSVTYGAGGS
TRERTHNTVARIARETPLAAAAHLTCVGASKAEIGEIADAYWEAGVRHIVALRGDPPEVG
GTFEPHPEGYKGAAELVEGLMQRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFTPDAYFRFLDKTLAAGIKADIVPGIMPVSNFAATQRMAAMCNTQVPSWMGRLF
EGLDDHPASRQLVSATIAAELCRSLYGGGVRDFHFYTLNRAELSFAICHLLGLRAAASNG
GTA
>A0A414MCB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides eggerthii|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESAFTPESNGYLHAIELQDQINQFNKGIFVDGSEMTVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMENGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTKEVLKCKNDAEAQQVGIEWCVQQCKELMEHHIPSIHF
YSIGAVNSIKEVARQIY
>A0A857DG13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter restrictus|TrEMBL
MKISEIFKVKKVLSFEIFPPKPTAAVTTIYDTIDQLRELTPDFISVTYGAGGGKNNTETL
EITSVVKNTYGIESVAHLPCINLSKTDVLEILDDCKKAGIENILALRGDASSSTKNGFQH
ASDLVSFIKANGDFHIIGACYPEGHKECASVVEDIYNLKTKVDAGADQLITQLFFDNQYF
YSFRERAVNAGINVPIEAGIMPVVNKKQIERMVTLCGVNLPKKFLSIMDRYENNPEAMRD
AGIAYAIDQIVDLIAQGVDGIHLYTMNNPYIAHRIYEAINTLLVA
>A0A839UNI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Simiduia aestuariiviva|TrEMBL
MSDELRISFEFFPPKTPEGKNKLYKVREELQQFNPDFFSVTYGAGGTTRDTTRGVVKSLI
EQGIDAAPHLSFGGDDEETVASLLSDYQQIGVKRIVALRGDLPSGMGGHSQLVYANELVA
FIRDRFGDQFHLEVAAYPEVHPEAKSYSDDIKFLKGKFDAGANSAITQYFFNPDAYFHFI
DQCQQAGIDAPIYPGIMPIINYRNLARFSDSCGAEIPRWLRKRLESFGDDVESLQAFGVD
LVSELCETLLENGAPGLHFYTMNQTQPTAKILRNLNGDD
>A0A062VE62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas polymorpha PS728|TrEMBL
MTPPAIQLPTAENAVRVSFEFFPPKTEAMNARLWETIQRLEPMAPAFVSVTYGAGGSTRE
RTHDTVRRIVAETTLRPAAHLTCVSATKEEVLAVAEEYWQAGVRHIVALRGDPPAGMGAK
FEAHPGGFVDSVDLIRGLRKHRTELGKCFEISVSCYPELHPESQGWDAEIAFLKAKQDAG
ADRAITQFFFEPEVYLAFLEKARAGGVTMPIVPGIMLQPNFNGLKRIAGLCGASIPSWLH
TLYDGLDEDEETRDLVTANVAADLCRKLQAQGVQDFHFYTLNRAGLALSTCRLLGLNPQS
AKAA
>A0A7Z1YYQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SMS_SU21|TrEMBL
MTTFSFEFFPPKTAAGERTLWQAIRQVEPLRPDFVSVTYGAGGSSRTRTIEVTRRIAAET
TLRPVAHLTAVGHSVAELRQIIGAYADAGIKDVLVLRGDPPGDPRGPWAAHPDGFTHAYQ
LVELVRSLGDFTIGVAAFPERHPRSPDWDTDIRHFVAKCRAGAHYAITQMFFHVEDYLRL
RDRAAAAGCDIPIVPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAARDDRAAGHRIGV
EYATAMAERLLAEGAPGLHYITLNRSTAALDIHRNVISSRSIRVA
>A0A4Z1F1Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrytis tulipae|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRAIDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDGFEQKLRDHPSGAFKDIPIIPGMMPIQSYQMI
KRTTKLSHAKLPSTIITRLDAVRGDDEMVKKVGVDILSEMVEHLKSTKSKYSGPRGFHFY
TLNLEKAVSFILERTELIPDAETVAALEPEYVPTIPDIADLMSIHSGSHKRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGPKNGFVFQKAFVELFL
PTADWKTLHAKLTSPELRDTVSFYASNSKGDFISSDEAVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSQTRKIIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLN
>A0A4R8H9R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orenia marismortui|TrEMBL
MLLKDKLKKKEFVITGELTPPKGTDCSKMFRVADELKGKVDAVNICDSPMATMKLNSIIA
SHLIQEETGLETIPHITCRDKNIIALQGELLGASRLGIKNILAITGDDPTAGDHPQAKAV
FDSNSISLIKAVQKLNTGFDINDNNLKGNTDLIVATAANLGAEDLDKEIERLKVKIDAGA
DFIQTQPCYDLDLLDRFLDKTKDFNIPILIGILPLTSYSMARYLANKVPGIEIAPSILER
MKDKDENEGIKIAREFLKDAYSKIDGIHIMSASRSDILLEVIDGIVK
>A0A2U2RQU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum|TrEMBL
MHSPMFTLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPGLKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRAAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFLGTQG
>A0A101E5R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldanaerobacter subterraneus|TrEMBL
MLKNEKLCNKLKEKKFVITVEISPPKGIDVTKTIEEARKLKGVADALNITDSPMANMRMS
PIALAHILQDHLNIETIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDNPSLGDTPQ
ARGVYDVDSVGLLKIIKALNSGFDYNGNKLDYPTSFCAGTTANPNDLRDEAIEKLHVKVE
AGAEFIQTQPVYDEEILFKFLDKVKDLKVPVLVGILPLKSYKMALRLMEKVPGIEIPEKV
IKRLQHGGKEEGINLSAEFIKNIKSEVAGIHIMPMGSVDFVFDIISKVEGIAISAKKAET
K
>A0A841D4U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planomonospora venezuelensis|TrEMBL
MSSHRFEVICEVEPPTRPDLKHVRHQIGTLGKVADAFLIPDNHIGRATVSSVAVAHEVEA
MGGRSIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTAGGRTSELNVRSMIEEV
RAASQDPAFAGVRPFRAGTAAGLRPLPAWKREADFMFLQVGFSLEALLRWREANPVDVPV
YAGVMVIASENHARRLAAAIPDIDIPEELVRRVSADRSAGVEAVCEQVLRIRESGAFDGV
HLVPVTRYREVAARLEDLLH
>A0A2N2EKE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-1|TrEMBL
MKNNSIKAYIEKNILLIDGAMGTYYASQENDYNHLSEKANLEKPEAITNIHNAYIGAGAK
LIRTNTFSANRYDMACSVQEVNKVLQKGYDIATACALNQDVFVACSIGPITETSESSETE
IMGEYYRIIDVFLNLGAKAFVFETFSQTDYIKKFVPYILDKNKDAEIIALFTINLHGYSK
KGIGYKRMIEELTNLNGLTAFGFNCGVGAGHLYNLYKNIDLEKNIYAAVPNAGYPEKIYD
RTLYMDNSDYFAEKIIDICKLGVKIVGGCCGTTPAHIQQISNYLETFEIEAHRKKNSIES
LRIVSQKKENPFWEKLDRGEFVVAVEIDPPFGYDISKLMEAAHILKAEGVDILTIADSPL
GKMRLDSLMMATKIYREVGIDVMPHVCCRDKNVIALKSVISAAYVEGIRNYLLVTGDPLP
DILRNEIKSVFNMNSVKLMSLVKEMNEELTNEDVFIYGGALNPKGANLDKIIEKVLQKKE
AGAKYLLTQPIYTEQDIQKLRLIKEKTGIKILGGILPLVSYKNAQFINNEFAGMNIPDVV
INMFNTKMSREEAEEVGIHISVELGKAMTPVVDGLYLMTPFNRATMIGKILKRLH
>A0A498G0Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobellus sp. Atlit-38R|TrEMBL
MSLGAQRGTEDGVQYLLSEARFELMPFDSFDDEIEELPNGASVAITTSPQLGIERTVERS
EEAAAAGYEVVPHVAARYVEDREQLEEIARRLTEAGITDIFVPGGDKEEPGEFESAYELL
VALDELPYDFEEIGITGYPEGHDFLSEETLAEAMEKKAPYATYIVTQLCYDPEAILEWTE
GIRARGIDLPIEVGIPGVMNYQRLLQISRKVGVGDSVKFLRKTTGIVGFVKQLVGSRGVY
KPDELIDGLAPYVGDEEYKFRGVHIYTFNQTPDLEKWRRGRLQ
>A0A843SJR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteitalea sp|TrEMBL
MTKFTDALAERVLVCDGAMGTMLYARGVFINKSFDAMNLTQAELVESVHHEYVSAGADVV
ETNTFGANRIKLGSFGLADRLRDVNIAGAQIARRAAVGRAYVAGSIGPLGIRIEPWGKTG
VDEASDYFREQVNALLEGGVDLFILETFRDLNEIGAAIDAVRSVSDLPIVAQMTTEEDGN
TLDGTPPERFAPELEKRGATVIGVNCAVGPAPMLETIERMEAVTRVRLSAQPNAGKPRDV
EGRNIYLCSPEYMASYARRFILHNVGVVGGCCGTTPEHIRQIKAAVRGAAAAAVSPAVRS
APVRQAPPIMAPPVPREQKSRFAGELARGRFVIGVELLPPRGFDADPAVQLARELKRNGV
DVISIPDGQRSGARLSALSLAVLIEQQAGIETLMHYACRDRNLVGIQSDLLGAHAMGLRN
LLLVTGDPGRVGDYPDATAVFDVDSIGLTNVVTRLNRGCDVGGQAIGAPTGFHVGVWVNP
AAANIDEELRRFDYKVEAGAELVVTRPIFDVASFERVLKRLESARLPIVAGVFPFDSARN
AEFMANEVPGVRVPDALMERMRRADGKDAARAEGIAIAREIAARLRTAVQGIQVSTQSGN
IDAALAVVDGLR
>A0A2P8LKJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. R9.37|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITQMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2N5NCY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus pasadenensis|TrEMBL
MSSTLKDKLLRKESGILTYGMTPPKSSHPPEKIREIADKQIERLRGAGIDGLVLYDVQDE
AERTDENRPFPFLKALDPTEYYEQYLKQELGVPAIVYHCVACEGPDKLASWILRGRDEQR
YSVFVGASSSRQQVQIRLPEAYRMSGILNERLLPGGVVIPERHRSKGDEHERARAKQEAG
CGFFVSQATFDVEASKSFLSDYYYSSRESGAEMAPILFNLAPCGSAKTLEFMKWLGISIP
KWLENELIHSVDILDKSVQLSRQVFRELYRFGLEKGIPIGCSVESVSTRKVEIEASIQLL
RDIREDMSRIGAELAPSIPSHN
>A0A4R3ID87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reinekea marinisedimentorum|TrEMBL
MNTPVPVSFEFFPPKTEVGYEKLLKAHDELKVANPEFFSVTYGAGGSTQERTIETVIELN
RRGVPAAPHLSCIGSTKETVHALLTRYKEAGIKRIVALRGDLPSGMMGTGGDFNFASDLV
RYVKAEFGDDFAIEVAAYPEMHPQAANLDKDIDHFVAKAKEGADSAITQYFYNVSAYKHF
VDEVRKRGCDIEIVPGIMPITNYSNLARFSDACGADIPRWMRKALETCGDDVQRIRSIGL
NFVVDLCNELIAAGAPKLHFYSMNQSGPTLAILEKLNK
>A0A424LYS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiaceae bacterium TMED74|TrEMBL
MPEHDQMRTSRLLGAEEIAVSFEFFPPKTDKMEATLWSAVDRLAPLMPEFVSVTYGAGGS
TRERTHATVTKLVKDTQLVPAGHLTCVGASKEEVDDVVRNYWEAGVRHIVALRGDPPEGV
GQRFEPHPGGYQNTAELVEGIRSIGEFDIAVSGYPEMHPESVSLKVEMDHLKAKVDAGAS
RIITQFFFNNSHYLRFVERVRAHGIWCPIMPGIVPIHNFRQVSGFAQRCGASCPPWLVHR
FDGLDGDPGTSHLVAAAVAAEQVMDLVDHGVRTFHFYTLNRADLVYAICHLLGVRPRQAR
ALAS
>A0A4Y9YHM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fomitopsis rosea|TrEMBL
MKKGMIEDALRDAKARGIKTILALRGDPPRGQEHWIPTDPRFTHAVDLVRFIKTTPEFAS
DFCVGVAAYPDGHPDKEIEEEGEIEYLKQKIDAGGDFIITQLFYDVDGFLAWVKRVRQKG
VTVPIIPGIMPIQTYASFLRMTKLCGTRVPPELMADLVPIRNDDQKVKDYGVDLAVKMIR
QMIASGDIRGLHFCTLNLEKSIVRILEDLGWIGGSLKSANKLITDTPAGLDERSITPHHA
ADSAAVSLAVAGPQPEGEAGKGELNNAASWDDFPNGRFGDYKSPAYGETDLWGSSILSRN
QAIEQWGNPRTLNDLTTMFLHHLHSKIATTPFSPTPLLPESLMIIEHLERLTRQGWWTVG
SQPTINGASSTDEVVGWGPRGGYVYQKCFVECFVEQKDLEEIERKVREKGEGWVDYYAAN
VKGELRTTVSPEGRNAVTWGIFPGQEVAQTTIIEEESFLSWKDEAFAIWEEWASFYPPGS
DERKLLDSVRNERWLLTLIHHDYSNPSALWEFLFKDDPVI
>A0A0U3QXL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CdTB01|TrEMBL
MVGRALRRLLEHVRYEVLPAAATEEKVLAHVPRDVVVTVTASPVKGLEPTLELTGRLAAH
GYRVVPHVPARLLRDDVHLKEVVTRLREAGVDDVFVPAGDADPPAGPYDGALPVLVRLGE
LGAPFARVGITGYPESHPLIHDDLTVQAMWDKRAHATYIVSNLCFDARVLGEWITRVRRR
GVALPLYVGVAGPVQRAKLLAVATKIGVGESARFLSRHPSWFLRFAAPGGHSPERLLERG
ETALTAPASGVAGLHLFTFNQIAETERWRRAALERLGG
>A0A2T2ZI44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia sp. MDA0666|TrEMBL
MSFDNVRGRSTPGRPSRTPSGTPSVVGQLGRRPDGTIPFSVEFNPPRDAAAEARLWRAAR
EFERMHPAFVSMTYGAGGSTRDRTARITGQLARETTLLTVAHLTAVGHSVAELRSIVGSY
ADAGIRNMLVLRGDPPGDPLGEWRKHPDGVEYAEELVRMVCELGDFHVGVASFPQGHYRS
PDLDHDTRYLTAKLRAGAEYSITQMFFDVEHYLRLRDRVAAYDAEQGAKPIIPELMPITS
LRTVQRAEELSGRPLPARVMQRLEQAAGNDPEANRNAVRAVGIEIATEIGQRLIDEGAPC
LHFITLNFAKATTEVLTNLGYTVTPAAVSA
>A0A0T9PYS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia kristensenii|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTRIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A6B2PEJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger sp. PrR004|TrEMBL
MTRPDISFEFFPPRNIEATFRLWDTVQALSPLGPRFVSVTYGAGGTTRELTRDVVATLHK
NSGLKVAAHLTCVDATREETLAIARQFKEAGVNDIVALRGDPPKGANGFTPHPEGFNSSI
ELIEALREAGDFNIRVGAYPDKHPEAPTATADVEYLKRKFDAGASEALTQFFFEAESFFR
FRDECEKAGIDKPIVPGILPIENWKGARRFAEATGTKIPAWVIEAFEKAERDDRQDLLAT
AMCTELCNELIEGGVDKLHFYTLNRPELTRDVCYALGVTPDNKLENVA
>Q2HBA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)|TrEMBL
MGDLVPSLELPPEAAKSHAMDKITDKIAALPAGQDYFSLEFFPPKTAMGFSNLRSRLDRM
ARALRPLFVNVTWGAGGSTATKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALDDAK
ALGIRNILALRGDPPRRAEYRDANEPEPEEEEEFSWAVDLVRYIRKTHGDYFCIGVAAYP
EGHADESHPLGQSLEHDLPYLVEKTQAGADFIMTQLFFDVEAYNHFEKTLREHPSGAFKN
ITILPGLMPIQSYQMIKRTTKLSHANIPDSLMARLDAVKGDDEKVKEVGVDILSEIVEQI
KEVKSRTDEPRGFHFYTLNLEKAVSFIVERTGLISPITPEEESAVIDQGPLPDIRLLRIN
GSTPDPSSHDPMRRKPSVGSDPRDRVIVQGRSTSYPDWEATALEASVPAEPINSRANTLA
ISEGEGVLGREATWDDFPNGSLHVTVAQARQLWGAPVSPPDISAIFIRHLRGELQTIPWS
EESFSAETDKIRDQLVALNSKGWWTLASQPAVNGLRSSDPTFGWGPQNGFVFQKAFVEFF
LPLADWAALEKRLNRPEMEGRREREASTNAVSWGVFPGKEIVPPTIIEEVSFRAWSEEAF
GIWGEWVKIYEKGSESERFLERVLADTWLVNIIHHDFLETDAL
>A0A1R4GU59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gulosibacter sp. 10|TrEMBL
MLSRQRFELVPAVDIVDRAVRSLEPGAAVSVTALPKQTLEETASTVLALAAAGFDAIPHL
PAGALRSREELSELLVRLEDSPVRALFVIGGDHDRGESPFADGGELLEAIRERSGDRFRL
GVAAYPEGHPAFDVEAGIRLLSQKAPLADFAITQMCFDAPAVAGFVRAASAAGIELPLWL
GTPARVSLARLARIGMRIGVGSSMGMLRHRSHRRLLGSFDPLELRAELEQELAELPEAAR
SLVAGRHVFTFNTLPKPAPAGRVAADAE
>A0A6I5GYM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID486|TrEMBL
MNPALTGSPEDTAPRPHGAVRHGRGARLLDDFSLEMTGKDVARLEEAGDTIPPGTRINIT
FLAGEDTTTRLTAARAVKRLGFVPVPHISARRLPSRPALEEFLGGLAADGTAENVFVVGG
DPARPEGPYEDALSVLRTGLLHRHGVRHVGITGYPDGHPGIADHALWTALADKAAAITAA
SFTGDVITQFGFDVDPVLAWLEDLRARGVHLPVRIGVPGPAGVRRLLGYATRFGVGTSAS
VARKYGFSLTNLMGTTGPDRFLHALAERCDPARHGVVKVHFYTFGGLRTTAEWITGFRQR
NTSAPPAA
>A0A7V4XI60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MTTESNLESLLREGHFVVCGEMSPPQGADKDAILRKSDYFRNTVDAVNLTDNQTAIARMS
SVMSSVFALEGGVEPIMQMTCRDRNRLAQQSDILGAYSAGVRNILCLTGDYMSFGNHPGA
KGVFDLDSVQLIRMVSDMNAGRFQCGEEMKAPPRMFIGGAANPFAEPFAMRIMRLGKKIA
AGAHFIQTQPVFDFPRFERWIKAVRDEGYDEQVYILAGVMPVKSAKALIYMKESVPGMSV
ADEYIKRMESATDPKEEGMAICVETMKRLREVEGIKGIHIMPVMWESITPRLVEEAGLLP
RPKPRMQDNLTSISDAELPPEVKKAGAAPKASGVEA
>A0A6N7B654|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellaceae bacterium|TrEMBL
MKKPHISFEFFPPQTPEGVEKLTAARKLLATLKPEFFSVTFGAGGSTQERTMETIQRIHQ
EGYQAAPHLSCVGSTRDNIRALLFAYKDLGIKRIVALRGDLPSGMASIGEFQYANELVSF
IRAQTGEHFHIEVAAYPEFHPQANSAREDMLNFKRKMSAGANSAITQYFYNADAYFRFVE
ESRKLGVTAPIVPGIMPIMKYSQLARFSDMCGAEIPRWMRKTMEGYGDDNESVQAFGRDV
VTQLCEKLIAGGAPGLHFYTLNQANASIEILKRLGYQ
>A0A7Y3LH96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MAKVVAESVKPTFSVELWPPRSPASEAKLEQTLPILEKLHPTFTSITYGAGGSTREKTHD
LVLKIKRETSTEPMAHLTTAAHNKSELVNILQRYLAAGVENILALRGDPPLSGDVALPPG
ELVYAIELVELARSMGDFSIAVAAHPEGHPDSPDLKTDRIMLARKLELADMAITQFFFDA
DDYSRLVDDLDRLGVSKPVLPGVMAPTSLKTLERMVLLSGAKIPQKVRRRLDGAGDDVVA
IKTIGVEIATELSAELLKRGAPGIHVYTMNDASTTVEICKSLGLG
>A0A7Y3KY55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MRIDQQLAAGFTRSFEYFPPKNDDEEAVLSRTLEDLEPLHPSFVSVTYRGGRESRQRTFD
LVADIVRRGQVSAMAHLICVGHRRDEVRDILEAYHELGVSNVMALGGDIPEDPALVASDF
AHALDLVELAREVGGFSIGVAAHPLGHPRSPSLASDRRYLAEKLARADFAVTQFFFAAPE
WSRLVHELADLGVERPVLPGIMPVTSLSSLARMSDMGAPVPDALARALEDAQHRGGPDAV
RRAGIDAAVQLCRELIDRGAPGLHFYTLNRSTATREIYERLFAEGS
>A0A7C6AFQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-3 bacterium|TrEMBL
MLRDKLKHKKIITLEVLLPTNVDIENLIKELQVFREYTDALNIPSNPLGKLRPDSLCFAH
ILQERVKIETIPHFVARHFTLLSFESQLLGAKALGVENILCVTGDSPVEGRSIFELNSAK
LLDVAKNLRQGLTSARKTITPIDFCLCTSFNPNVPNIQGELIKTGEKCRCGAEVFFTQPV
FQPERFIETLKELRRRHPDIKIVAGLSFLYTKKRAFSLMKFLGIPYQYITKIEEVNESEL
LLETAKKLKDYVDGFYIIPIGKYANAIDLLRQIRQIL
>A0A7V5CJQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MGSGNLANAVRNGQFVVMAECTPPRSIKTDQLKSCISALSNMTHAMSVPECEDGIRMSSL
AACIHLAAAGAEPVLHILTRDSNRIALQAMILGAASMGINNIFCTTGRHQVLTSSRSARG
VYDIDQIQLLTIADKLRKTGELADGQSIDSPIDMLLGTETNPFSDPMELQVMALEKAIAA
GADFIVTAPVFNLEKFNTWMDMLRQRNLVERACVIASVMPILSSQQAADLAQKYSHLDIS
DDIVRRLDSASDSKSAGIDLAREIITSLRATDGIRGIHLVTGEDFTLAKEILSISGLARS
>U1N1S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloquadratum walsbyi J07HQW2|TrEMBL
MSMYDVSNMALGAQSAVDQDGVSNLLRGARFELMPFDSFGDELESLPAGSSIAITTSQQL
GIEQTVERAEEAAVQGYEVVPHIAARYVEDKTQLASIAERLSDAGVSDVFIPGGDREEPA
GEFTSAYDLLEALDELPHSFEEIGITGYPEGHDFIGEEELATAMDRKAPHATYVVTQLCY
DPETILEWVESTRERGVDLPIEIGIPGVMNYQKLLQISQKVGVGDSIKFLRKTTGIFEFV
RQLVGSRGVYKPNDLIDGLSPYVEDEYYNIRGVHIYTFNQTPDLESWRQTRLS
>A0A7C5N562|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polyangiaceae bacterium|TrEMBL
MKIKDMFRGGERVVSFEFFPPKTDKGMESLYEAVEALERCRPSYVSVTYGAGGSTRDRTV
DLVSRIKNELGVETMAHVTTVGSTKDDIKNVLDRLAEAGIENVLALRGDPPKGEKTFQKT
EGGFGYASELVEFIRSEGYPFSVGAACYPEGHPETPDLDQDLKNLVVKVKAGVDFLITQL
FFDNQDYFAFKRRCRHAGIDIPIVPGLMPVTNVAQIERFTTMCGARIPQELYRRLKIVER
DPKAVVAA
>A0A540X393|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcus llanfairpwllgwyngyllgogerychwyrndrobwllllantysiliogogogochensis|TrEMBL
MKIRNRLNPSNPCFSFEFFPPKTDEGVANLLKTLEDLAPLEPGFVSVTYGAGGSTRDRTL
ELVTRIKAETGIEAMAHLTCVGHTRQELRELLQRLADAKMDNVLILRGDPPQGQKSFVTA
EGGFTYATELVRFIREEDFNFCLGGACYPEGHVETASRDDDLRHLKAKVDAGLDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNFEQVQRFTRMCGATVPMRLGLQLERVKD
QPDAVVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRART
>A0A1F9PR92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium GWC2_61_20|TrEMBL
MSTFPGRSQAFLAQLQERVIIGDGAMGTLLYSRGIPLDGNFEHLNLVRPELVRQVHADYA
AAGARLLETNTFGANALRLGAIGLEKKVAAINGAGARLAREAAGADGFVAGAVGPLLPPR
GETTELTPEAKSEIFTQQMSALAEGGVDLFLLETFTSLEDLELALAVSATLGLPALAQMA
FLEEGRTRAGVSAEAAVRRLSAAGAAGLGANCGGGPRELLRVLERMARVTALPLSAFPNS
GFPEYHDGRYIYLATPEYFSAVARDMVAAGATLIGGCCGTTPEHIRALSAALAGSRPAPR
PRPVPSAVVPAATATAPPELAGTFLASWGKRTVVTVELDPPRGLDCRKLIVGARALTAAG
ADAISLAENPLARIRLGNIAAARTLHDEVGCATIVHITGRDRNLIGLHSDLMGAHLLGLR
NILAVTGDPVAVGGESGASSVFDLNSVGILQLLAALNGGHNLLGAELDGATSFLCGAAFN
PNLPSMDGQLRRLQKKIAAGARFVQTQPVYDVAILEELVTRTAPLGIPVLVGLLPLVSER
NAEFLHNEVPGITLPPAVRARMRGKHGAAGVSEGMAIARELIEAGRGQVGGWYLMPPFGK
IDLACELMASIRATSPAPLR
>A7E9M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSDE
YRAVDEKNGDLPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDTFEQRLRDHPSGAFKTIPIIPGMMPIQSYQMI
KRTTKLSHAKLPTNIIRRLDEVRGDDEMVKKVGVDILSEMVEHLKSTKSQYSGPRGFHFY
TLNLEKAVSFILERTELIPDAETVAALEPEYVPTIPDIADLLSIHSGSHRRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATALEAGVPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGVKSTDSIFGWGPKNGFVFQKAFVELFL
PTSDWEALQAKLTSPALRDTVSFYASNAKGDFISSDEAIGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSETRKVIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLN
>A0A0M8PA33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium nordicum|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKALGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRQTHGDYFCVGVAAYPEGHPADIFQDVQDPARDIPY
LVEKTLAGADFIMTQLTYDIEAYQKFENALRSHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIARRMEEFKHDDDAVKRAGVDIVSEIVGGMRDIPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPSYSDAGELAIEDDPASIPLDFPGRALRRRRASSINSQPHNRVIVDKL
SVHESSQDSVHEALADSAGMPAPPPNRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTANSARRLWGSPVDSKDMSTLFRRHVSGELHMVPWSEGGAEEDGDG
LNAETELIRPELLKLIDGRGWWTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFC
SSNDYTNILKPMFAKHGHDKLTWFATNIKGDFESSLPIQPADVELDDLGSNPESVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPSETYLDTTKNDSWLVCVV
GQQFGAGTKQGSKEEEDEVKWMWRVLAGEEA
>A0A532VCA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium Ae_b3b|TrEMBL
MSFSDVLKSGKFLITTDVIPPKGINISKMLSRIDSLVGKVDAVNVVDLPSSVMRVSPLPI
ALLLKERRLEPILQMTCRDRNRLALQADLLGGYIMGITNILALTGDEIHLSDDPEAKPVF
DLDSIELLKAARKLEKGYDLGGNPLRGLPKFCVGAVVDPGANPIEPEIEKMQRKVEAGAE
FFQTQPIFDVTVLVEFLEKAGEVEVPILGGVLLLKSAKMARFMNEKVPGVRIPEHFIHQM
EKTQDPVQTAIKITSSIINQIKGTCRGVHIMTLNWEDKVPAVLKAASF
>A0A0Q8PK17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora sp. Root187|TrEMBL
MALGIPSTRTDRADTVRDLLAAGDRSFSFEFMPPRTEAGESKLWDAIRRVEALDPNFVCM
TYGAGGSSRGRTVNLVGRIATETTLTPVAHLTAVDHSIAELRNIIGQYADEGVRNVLAVR
GDPPGDPEGEWVRHPQGVEYAYQLVELIKSIGDFCVGVAAFPSMHPRSESWDDDIRHFVA
KCRAGADYAITQMFFEVEDYLRLRDRVEAAGCSTPIIPEIMPVTNIRQLTRFPQLSGSEF
PPELQRRFEAVAEDPEAVRAIGIEHATAMAGRLLAEGAPGLHFITLNHSTATLEIYQNLG
LHQR
>A0A3C1L945|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MARISDLLAAGPTYSVEFFPPKHEAGWLSLGRTISELEHLAPDFVSVTYGAGGSTRTRTA
DLVSWVRRQTSISPMAHLTCAGHTRDDIRAILTDYRAEGVENILALGGDLPADGETESDY
LFSMELVDDVREFGGFSVGVAAHPELHPRSPDRGTDRQHLANKLAAADFAITQFFFDIEH
YLVMIDELASLGVTKPVLPGIMPISNLGQITRMAHMSGAEVPGWVIEAMEKAGDNLDAAE
RIGVDLATELCARLIDEGAPGLHFYALNRSWATREIFRNLGLRPAL
>A0A1H3KGN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. 166amftsu|TrEMBL
MKILDLLSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADLIQTN
TYGANEAKLRMYGLENRVAQINKAAVKLAKAAVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEKVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQLALHEAGTTQNGN
DVNEVLKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPAHIERMKRAIANVTPVTEKQIVQKQQVVH
MQTKRASTHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADLITLADNSLA
SPRISNMAMGALLTKHDIPVLMHLACRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMDGHETQGAAVEEGIRISQELIDAAMKYFNGIYLITPFLKYEITENLVKYVK
EKQEMKEGIY
>A0A352W2C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetia bacterium|TrEMBL
MQALIDNRRYLIEAAPPRQSAKDLEAELKKFKARYLTILERGHAVCITDNAMGHLSFQGT
ELIKELSLPTAAGRVLLHLNTYHSGKNLDQILQTAAELGTTDILVITGDGSERLPKLAPR
EIGSDSINTSSVDLIKYIHREYPGKFTLGAAYNQYEPHDFEQKKLEEKIRAGAAFIIT
>A0A7X1V5C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFEIIGACYPEGHPDSPNQISDIQNLKRKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRTA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQSLG
>A0A150RUE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
GGADILVLETFRHLDEIKLAIEAARKAAPGLPVLASMTFDTSGVVADGSLPERVAQTLRD
WGVDLLGVNCGDGPQLSLAMAERMATAGLPLCVQPNAGLPRTVDGRLLYMATPEYFDVFA
RRLIQAGAAMIGGCCGTTPEHVKWMAKSARMLRGAAAPEATSRPQITIDAPTGSEPTPLG
ERSPLAAKIAAGKFVVSVEVNPAPGLSPESALNAAKMLIDSGVDVVNVADGPRATARMTN
LAFCALLLQRFGIEPILHVCGRDRNLIGQMAHLLGAHAIGLKNLVIITGDPPKVGDYPEA
TAVYDLDSIGLLHMASTMNRGLDPAGKPIPGGKTSFLLATGLEPGAPDLDKEIARLERKR
AAGADIIMTQPVFHQDVLEKVLRRIEHLGMPVLVGVLPLVSYKNAEFLHNEVPGMQIPEE
IRERMRKVPAGAEARKEGVKIAREMLFSVRDRVQGAYLMPPLGKYELALEVLDGLKTS
>A0A077L4A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter guillouiae|TrEMBL
MQEVLPVATQLAGFPVCMTLSDRVRSDEDIAPLIAAQSYPQQIEKVLHYAGKGRDIHDFN
LFLTQAKQHGQQNLLLLTGDKLKQHHDGQGSHARTRYLESVNAVIAAKQQGGFHIGVALN
PFKYSQAEKQAQYLKLHKKLQAGADYIITQLGFDLVALKQAHEFLIEENYTQKILACVMP
LTLARAKFMLKHNVAGIVITPHMLEVLAQEHDSDQTENTYLRCALQILICQHIGYAGVHL
SACHKADEQAILTSYIEQYRHLDLKQCQQLWTQLWQLKTGNELRPAVVEKSKLSNLHQKV
KYQFLDTIHSTMFNSSLVKGLGAYIFSAGFWNKALAAKLLLQAEYLSKHFIVGCESCGQC
RLAETLYICPETCPKGLANGPCGGTHLDRCEFGDRECIHSVKARLAEEVDQIQVLKKQLI
PTVPIEIRGTSSWKNWYVKQ
>V7HFT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L103C120A0|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A3B0TZB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKNKQSAIGETGQAGQAGRRKFDISFEFFPPKTEAAEKRFWASMEKLTPLKPRFVSVTYG
AGGSTRERTLRMVSCITKETGIEAAAHLTCVGASRGEVDDVVRQYAQAGVHRIVAIRGDP
SGGVGHEFIAHPDGYANAAELVKGIKAIGDFDVSVAAYPEKHPESATWEDEIDNLKRKID
AGADRAITQMFFDNAHYWRLMERVEKAQISLPIVPGIQPIHNFAQVASFAKKCGADVPDW
LASRFEGLENDPETQALVAALVAGQQVAELANGGVSQFHFFTMNHASQVMALVRVLDQEP
KNDNNA
>A0A2Z5UIJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. FD7|TrEMBL
MTSNLDALAEARRAAASPLFANLDGDVGVSFEFFPPKSAKMEAQLWETFRTLEPLDPSFV
SVTYGAGGSTRERTHATVARIAAESRVPAAAHLTCVEASRAEIDAVARAYWDAGVRHIVA
LRGDMPGGEPYRAHPNGYANAVELVAGLKAIAPFDISVAAYPEVHPDADCPQADLDNLKR
KLDAGANRAITQFFFSPDSFLRFRDSAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMVSLFDGLDDHPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVSTRKDQAA
>A0A1J6K792|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nicotiana attenuata|TrEMBL
MKVIDKIHESAKTDRVVFSFEFFPPKTEDGVDNLFERMERMVSHNPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPASGIATQETYENDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPADITAALEPIKDNEEAVKAYGIHQATEMCKKILATGIKTLHLYTLNMEKSALAILMNL
GLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDEYPHGRWGNAQNP
SYGALSDYQFMRARSRDKKLQEEWAVALNSVEDIYGRFMNYCLGKLRSCPWSELDGLQPE
TKIIDEHLGNINTKGYLTINSQPAVNGAKSDAPSIGWGGPGGYVYQKAYLEFFCSHEKLN
ALVEKCKSFPFLTYMAVNKEGNWISNANQTDINAVTWGVFPGKEIVQPTVVDPASFMVWK
DEAFEIWSRGWAQLYQESDPSRKLLEQVQNSYFLVSLVDNDYINGDLFAIFKDI
>A0A3B1DC19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MRIGEIYQAGKCAISMEIFPPKTEDGDALLRRTLGKLTAYQPAFISCTYGAGGSTQQRTL
DWSVEIQMQYQQTATSHFTCVGATRDELIDWLTMADNRGIQNIMALRGDPPAGEETFQQK
EGGLQYANELVALIRENFPDMGIGVAGYPEKHPTAPNAKTDLVNLKRKVDAGADAVYTQL
FYDNDQFLKFRDQYQQAGIDIPLIPGIMPITNFSRIQRITSMCGASIPQEFFSQLEKAQE
DKEAQFEIGVQFAIKQCSALIKAGVPGIHLYVLNRSKAIEQIMQALGYGL
>A0A3B0VTZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKNIKFSFEFFPARTSEQKIVLRNTQDKLRKLNPEFFSVTFGAGGSTVEATAETVLELKK
HKTPLVIPHLSCMGGTPDSIKMLLQKYLDNDIRHILALRGDVPSGMGSVGYFRHANELIE
FIKTEFNDAFDITVGCYPEIHPESETKETELKFFKQKVDSGASQAITQFFFNADAYFNYV
EECQKKGINIAIIPGIMPITNFSNINRFCGFCGAEMPRWLKYKLQSYGDDRNSIQQYGTE
FISKLCEQLLQGGAPSLHFYTLNRSKATLDIV
>A0A1Y3W8H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drancourtella sp. An57|TrEMBL
MKIRENLQSGKVHISFEVFPPKTDDKYESVLKAVDEIATVKPSFISVTYGAGGGTSKNTV
GIASHIQNDLKVPSLAHLTCVSSTKAEVREVIKKLKEEGIENVLALRGDIPEGMEYPAED
KFQHAIGLIELLKESGDFCLGGACYPEGHVESATQKEDIRHLKEKVDCGLDFLTTQMFFD
NHILYNFLYKIREAGITVPVLPGIMPVTNKSQIKRICSLSGTYLPERFKAVVDRFGDNPK
AMRQAGVAYATDQVIDLIANGINNIHIYSMNKPEVARAIMENLSEIVDE
>A0A2M9A4X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hallerella succinigenes|TrEMBL
MKIIDILKKNKMSLSFEVFPPKKATSFESVKSATESIAALGPSFMSVTYGAGGGVSQYTL
EIAKNLKTKFNVSMLAHLTCVSSSKETVKQRIADMKAAGIKNVMALRGDLTPELIENNRE
KCDYHHAIELIHELKASDADFCIGAACYPEKHPESANQREDIQHLKEKVDAGADFLTTQM
IFDNNLFFSFLYKLREAGVTCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPDAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFV
>A0A1W1DB51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MQLSFEFFPPRTDQGKQNLRQVRQELSVINPHYFSTTFGAGGTTQDATLETVLDIQANDG
IPAAPHLSCIDSEKSKILSLLNQYKDAGINRIVALRGDIPSGVRDIGDFHYANELVEFIR
TEFNDHFHIEVAAYPEMHPQAKNMQTDIAHFVNKIKAGADSAITQYFYNADAYFRFVDEI
QKQGIDAPITPGIMPITNHDQLMRFSTMCGAEIPRWIEKRLSGYGDDMQSLREFGFDVVA
NLCDQLKTQGVDNFHFYSMNKTQPSLQLAKILM
>A0A077KBF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. StRB126|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINNLGRGKYLHNEEQICDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A429E7N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. WAC 04197|TrEMBL
MATPPAAVPAQRTARPRTVRDRLAAGVPMISLEFMPPRPTDDADRIWRNVRKLESLRPGF
VSVTYGAGGSTRDNTVAVAARIARETTMLPVVHLTAVDHSVRHLRSFVGQLADAGVVNVL
ALRGDPPGDVDGEWVRHPQGLTYASELVALLRDHGDFCVGVAAFPHRHPRSASVEDDTAH
FVAKCRAGADYAITQMFFDADDYLRLRDRVVAAGCETPIIPALMPVTTTRTIERSEQLSG
APFPAHLAARFAAVADDPKAVRALGIEQAILLARRLQDEGAPGLHFITFNYAKATKEVVA
ELTVPG
>A0A3B1A3R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MESQKKHPKHFSFEFFPPKTPEGAEKLKTVRSELGKLKPKYFSVTFGAGGSTQDGTMDAV
LDIQKAGFNAAPHISCMGTDKEIIVSLLEQYKNNGIKQLVVLRGDMPSGAGSGNHGDFSY
ANELVGFIRNKYNDHFHLEVAAYPEFHPQAVNAEADLDNFKRKVEAGANSAITQYFFNAD
AYFQFVDACEKRDVFIPITPGIMPITNYTQLARFSDMCGSEIPRWIRKRLEAYGDDKASI
RGFGEEVVTHMCERLLAAGAPGLHFYTMNQTGPTKALWNNLNLSQV
>A0A7Y8PQ66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. SwsAc5|TrEMBL
MTKQVPISFEFFPSKTDVGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLSTISDFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYASDLVR
FIREHSGDHFHIEVAAYPEMHPQADHFDQDIKNFVTKVNAGANAAITQFFFNPDAYFYFV
ERIQKQGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIIKLCERLIAGGAPSLHFYTMNNTEPTRQLVTDLGLA
>A0A521PH49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium sp|TrEMBL
MSPAQSALGPVARAGVGGKERPRVSFEFSPPKTAEAEENLWAAIRRLEPLNPSFVSVTYG
AGGSTRDRTHRTVLRMLKETTLKPAAHLTCVEASRDDVDEVIRDYWASGIRHIVALRGDP
PGQIGGVYTPRADGYCNATELTAGIKAVGDFEVSVGLYPHVHPESTGIDHDIDVLKAKID
AGATRAITQFFFDVDGFLRFMDRVRKAGVTIPISPGIMPVTNYTGLKKMSGPIGIQLPAW
LGNLFDGLDKDPETRRLIAASVSSEMCARLAEEGFGDFHFYTLNRADLTYAICRVLGVRE
TPPEPKEAAA
>Q8GGL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces atroolivaceus|TrEMBL
MSTLRDILASGTPTFSFEFFPPRTEAGSRMLWQAIRRLEALSPTFVSVTYGAGGSSRDRT
VEVTKRIAAQTTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPNAPWT
PHPQGFTHAHELVRLVRNLGGFSVGVAAFPERHPRSADWDSDISHFVAKCRAGADYAITQ
MFFDVEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSNARFPAALADRLEAAA
GDPAEGHRIGVEYATSMAERLLAEGAPGLHYITLNRSTATLEIHENIQSIRTSRSTHALA
AAR
>A0A0A0EM80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter concretionis Ko07 = DSM 16239|TrEMBL
MTPISFEFYPPKTDEQRVQLDRTAARLKAHDPDYVSVTFGAGGSTLSHTPEAIQRLRSEH
AYDAAPHITCMGGSRAEIRNLLKLYRAMGARRLVTLRGDVPSGMVSPGDLRYASELVEFI
RAETGDHFHIEVAAYPEVHPQARDAHTDLAHFLAKARAGADGAITQYFYNADAYFRFVDD
VRAAGIDIPIVPGIMPISNFSQIRRFSDMCGAEIPRWVSQRMLAYADDVDSVRAFGAEVV
AQLCQRLIAGGAPGLHFYTLNLARPTLGVLSQLA
>A0A0Q7A0X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Root401|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRNLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSSSIQSFG
EDVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A451CFN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. G|TrEMBL
MNIRRSDPQVFSFEFFPPKTPNGQNNLRATRQRLADLHPHFFSVTFGAGGSTQSGTLETV
IETQRETGIQTAPHISCIGSTRDKIRQILDSYLDAGIGRLVALRGDLPAGMTEAGEFRYA
NELVEFIRAETSDAFHIEVAAYPEVHPEAPSAEADLENFKRKVQAGANSAITQYFYDVDA
YVGFVENCQRIGVQIPIIPGIMPITNYASLANFSERCGAKIPQRLAGRLEGFGDDLAGLQ
TYGIDVVTELCRRLLEAGAPGLHFYALNRAEPSVTIWKNLGLPS
>A0A3C1M295|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium UBA8156|TrEMBL
MSNFQAAIAQREFLVTAEISPPKGIDLQRAIALAQKLQPWVHAVNLTDCSRAVLAMGSIA
TAVVLQQQTGIDTICQLTGRDRNRLALQGDLLGAAALGVRNVLALTGDPVKAGDHPEARA
VFECESIRLLQLIAQLNQGYSANGQLLPDGGTCFWAGAAVDPQSPSWSGLSRRFERKVAA
GAQFFQSQLICDFERLALFMEKLGKPAGKPILAGIFLLKSAQNARFLNKYVPGVNIPEAL
IARLERAPNPLAEGIAIAAEQVQQARQICDGVHLMAIKAEERIPEILTQAGVTPRFHPPT
NTP
>R7ECK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:471|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMFGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLEEGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMVKFMNNNVAGIHVPDEMIEE
LKADKERTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A6G7ZQ20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sinipercae|TrEMBL
MNLPEQLPARSCIPLFAEARGDIELSFEFFPPKSDAMGETLWQSIQTLAPLRPRFVSVTY
GAGGSTRERTHATVERILTETELTPAAHLTCVAASREEVDAVAREYWDLGVRHLVALRGD
PPEAGARFEPHPEGYANAAELVAGLKQVAPFDVSVAAYPEMHPDSGSRAADLDNLKRKVD
AGADRAITQFFFSADSFFRFQDDVAAAGIDIEIVPGILPVTNVATTRRFAGQCGAAIPDW
LNQSFEGLDELPAARQLIAGTVAAELCGQLYAGGVRHFHFYTLNRAELSYAICHLLGVRA
KA
>A0A7X0B3U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirillum iridis|TrEMBL
MSRTDTQQPGSLLNGYSFEISAKDAIRLDAIRAIVPSGTIVSITYLPSETDDARIAAARQ
VRELGFIPMPHVAARRIPSADGLQRFLNRLAIEAQVDRLFVIAGDSAEPAGPFVDALSVI
TGAQLGDHGIRSIGIAGYPEGHPQISTDKLNRALADKSAALTDFGFSGEIVTQFAFDADP
MLTWVAGLRAAGIRMPVRLGLPGPANVGTLLRFAARCGVGASTKVLAKYGASITKLLHTA
GPDHLYNDLARSIEMEQHGAVAVHLYPFGGLQKMADWAHTTKSRTS
>A0A838IEQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradymonadaceae bacterium|TrEMBL
MSQTQMRQSFLDAVRKGPIVFDGAVGTQLYERGIYINKSFDDANISNPDLVASVHAEYAA
AGANVITTNTFSSNRIKLRRHGLEDRLRDIVTAGVRLAREAAGDDHFVAGSIGPTGLTPT
MLTDEELRDIHDAFCEQATLLADSGADVIALETFRQLSEIKIAIAAVREVCRLPIVAQMS
FDTEHKTGDGASPERVALLLKQWGADVVGANCMEGPNVIYDVILEMIGCGAPVIAQPNAG
YPRKVDERLVYMATPEYFGVYARRFFQAGCAIVGGCCGTGPEHVRQIAAAARMMGGGRIH
VEQSNEVRVIVPDADSSTEIPAYDRSALSSKIMRVYKERVKAAPGTATALSPDSFVVSVE
VNPPAGLDPSRAIEAARMLRAGGVDVINIADGPRASVRMANWALGGLMARELGTEVILHL
CGRDRNLLGLQSDVLAFHLLGLHNLVVVTGDPPKVGDYPHATAVFDLDSIGMLRMIQGFN
RGIDPAGKPVGDVTRFFCACGAEPAARDYERELRRLEAKKTAGAQFVMTQPVYDPDVLDR
FLRDTEHLDMPVLVGLLPLASYRNAEFLHNEVPGMAVPEEIRRRMQLAKGASGARREGVQ
IAQETLDAVKDRVVGSYIMPPFGRYEAALEVLECIDGYGSTPSDQE
>I2JRU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brettanomyces bruxellensis AWRI1499|TrEMBL
MSMKITDKINALDKDEPFFSFEFFPPKTEHGMRNLYARLGRMSLMGPLFVTVTWGAGGXT
AEKSVDLAITCQKELGLTTCLHLTCTNTTKKIIDKALASAKAAGIRNILALRGDPSRTSE
VNKLSKEEAPFQYAVDLVKYIREQYGDYFCIGVAGYPEGHADGFYDESQDPHKDMPFLVE
KINAGADFVLTQLFFDDRSFINFDALLRSQADLKNKEIPVIPGLMPINSYDVFKRATKLA
HATIPDSVLGRFSEEIQCDDDRVKEIGVDIMTEMIEDIHEKTSVHTRGFHFYTLNLEKSI
AQIVNRSSLLSQVVDKKERELEECVSDSSDDEIDDNVTTAKRAAYMNRFKQPTNQIIVED
GKHKDSAAKTLASRQIKRRSSSQFQKIMSISSGHGALGKDATWDDHPNGRFGDXRSPAFG
SSGYGPYGPSLHVTPEKAFELWGQPETMDDVSSVFVNYLSRKVDAIPWNEMSINPETALI
QEPLIILNQHHRFTMSSQPACNCAQSADKIFGWGPAHGYVYQKAYVEMFVSKEDWKKNIL
PKLKGNPDVSYYVGDSKSYFDSSLKAKDTNCVTWGVFPDRQIVQTTVVNEDSFKAWKDEG
FQIWREWMMLYPGXSPSANVLKEVLDGYYLTAIVHHDYPDEDALWDLLVGDTE
>I5D3Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia hospita BS001|TrEMBL
MNPIELSFEFFPPKTQEGLDKLRATRAELLPLKPKFVSVTFGAGGSTQQGTLDTVLDMAK
DGLEAAPHLSCIGSSRESLRAILNEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFRIEVAGYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DAHKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VADLCRRLVEAKVPGLHFYTLNGSAATKAICERLVG
>M6YZY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira santarosai str. 200702252|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSRLDPDFVTVTYGAGGSTRSK
TAQILSEISKNYSFPTVSHFTCVGANQEQILKTLKEIRSSGIVNLMALRGDPPKGEGQFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPNAKNLEEDVENLKRKVDAGADFLVS
QLFFVNSIFENFLNLVRAAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A1W2B7Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocicer vacuolatum DSM 3385|TrEMBL
MNLTENLGKKFVITTELGPVKGVLADKSLEKAGEYLSLDGINIHDCPMGNLRINSVAMAS
LVQNKLGIEAVPHFTCRDRSLLGTQADLLGAHALGIRNILVTTGDPPKHGPYPSKPVYDY
STFELIRLIRKMNSGLDYNEKEFGGKTDFKIACTAMPTARNPERELERMKKKISAGADFF
QSQVVYDSEKAVSFLREARKLGKPILTGVMPLKSVKMARFMNKNVEGIDVPEEVISRMEN
DGADGIEITCDFIKEIAEHTDGIHIMAMGDVKGTNRIIEFVNTLVGR
>V1HDN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. indica serovar 6,14,25:z10:1,(2),7 str. 1121|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A658GI96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SST3|TrEMBL
MTSPRPSISFEFFPTKTEAGHEKLLATARRLAEYTPDFFSCTYGAGGSTRDRTLNTVLQL
DGDVKVPTAPHLSCVGDSKQELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANE
LVEFIRAETGDHFHIEIAAYPEMHPQARNFEADLANFVRKAKAGADSAITQYFFNADCYF
YFVERVRKLGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMESIQAF
GEQVISEMCEELLTGGAPGLHFYTLNQAEPSLAIWNNLKLAR
>A0A0S9Q823|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. Leaf112|TrEMBL
MPTASQHRASRDGYRPISVSIEFFPPKTDEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETGLRPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPQDGVG
TTYRPHPGGYAQTADLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFENEIYLRYVDKVRAAGIDIPIIPGILPVQNFKQSANFARRTGASVPYWLAARF
EGLDNDADTRRLVAAAVAAEQVLDLVDRGVNDFHFYSMNRSDLVYAICHLLGLRSQAPKV
AAAKAA
>A0A3A9TKU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus opacus|TrEMBL
MTNLSNETGVRRRSTNAADLVRNMSYEVMPFKNTEQDVLDHVPKTVPLTVTVTEAKGIET
TLNLTERLIGHGYQVSPHLPGRQFVDDAHVADVIARLSEIGVKSVFVIGGDAPNPAGKFV
DAFGLLRAMEEVGHPFQEVGIGGYPEGHGAIEQELIDLALQQKAPLATRVLTQICFDATT
TSTWAAGIASSGVDLPTYVGMPGPVSRQKLMRISAGIGLGQSARFLQKQQSMLWRFLLPG
GYNPTRLLKQLGSAVPKTSNNVAGLHIFTFNELRKTEIWRQKLLTAIVEKDARS
>A0A1B7LGB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotomaculum copahuensis|TrEMBL
MKLSSLFAQGKFVVTSEVGPPKGTDVSGMLAEAEHLKGVVDAVNVTDNQSAVMRLGSLTA
SHLLKQKGFEPVFQLTCRDRNRLALQSDLLSAAVLGIENVLCLTGDHVHAGDHPQAKPVY
DFDSVQLLRTARELCNGFDAAGNQLDGKPDFCLGAVVNPGADPLEPQLIKLEKKIKAGAQ
FIQTQAVFDPAVFEKFIKQASSFGVPVVAGIVLLKSAGMGRYMNENVSGVNVPDSLLREM
ADLPAEKRKEKSAAIAVKLIKELKQMCAGVHIMPLGWTDLVPGIVSAAV
>A0A7C7RX10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteriaceae bacterium|TrEMBL
REGLHNLLILTGDYPRYGYRGRAKPVFDLDSVSLLRLISEMEKGFRLPPEVPGGGITLPP
IPFFAGCVVNPFKWSEAETVTQYYKLIRKLRAGARFVITQVGFSARKFQEVKFFLEEEGF
GEVPILGSILVMDVRLARLLYRGAVPGITVTERLLKTVEAEARRPDKGREAALLRAAKLM
ALLKGLGFQGAHICGAPLDLVAARELLAMAEEFYPSWKEFLPEFSEAPERSFFLYDRDPE
TGLNLRRRRDLSPRSVRSLTFLFSGLIHRLFFSSKAPFFRLTKSFFEKLSGSRFEKYLAR
LEYGFKKLLFDCQECGDCMLGELAFLCPQSQCAKYLLNGPCGGSQDGWCEVYPGKRRCVY
VRIYERLSPEERRKKLLENEIPPRNWALYRTSSWLNFYMGKDHHSFTDPPEELEEARGSC
PWKPQARRVAGVE
>J4TZ22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces kudriavzevii (strain ATCC MYA-4449 / AS 2.2408 / CBS 8840 / NBRC 1802 / NCYC 2889)|TrEMBL
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALESAYHSGCQNILALRGDPPRD
TDSWTPVEGGFLYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDAKLDLEYLKQKID
AGGDFIITQMFYDVDNFISWCSEVRAAGMAVPIIPGIMPITTYAAFLRRAQWGQISIPQA
FLSQLEPIKDDDELVRDIGTNLIVQMCQKLLNSGYISHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANRCLELWSTPASINDIAFLVINYLNGNLKCLPWSDVPIN
DEINPIKAHLTELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDILKNNEFLTYFAIDSQGDLLSNHPDNSKANAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILDEWKLNMDKYDKPQSSQFIQSLIDDYCLVNIVDNDYISPEDQIHAILLSL
>A0A533T651|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium sp|TrEMBL
MLVKEILNAAIKPVFSFEFFPPKKDEDWDTLFETILALSPLNPSYVSVTYGAGGSTRSKT
HSLVTKIQKETGLTVVSHLTCICSDTVETGTILQNYREHGINNVLALRGDKPAGTASIAE
ATKDFPHAVDLVRFIKSNFPDIGIGVAGFPEGHPEVPNRIKEIEYLKEKVDAGADYIVTQ
LFFDNRDYFDFVERCAIAGITVPIIPGIMPVTTQKGMFRMSELALGARIPAPLLKKVLAA
ENDTDVASIGIEWATDQVQELIDHHIKGIHFYTLNMADATLRIFNHLHQ
>S4J074|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis JCP8066|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIRSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A013U5B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 573719|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINCIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A4Q7Y2N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus saxobsidens|TrEMBL
MNRVLTVRDPNTRATLRRSFETLGYEVIPFKKTQEQVLRHVPKDVRLTVTASPAKGQDAT
IDLTVALAGHGYEVAPHLSAQQVQDRAHLADIVARCREAGITDVFVVGGDPTETPTEFKD
AHALLVALHELDHGFTDIGIGGHPEGHPSVSEDVLFQALKDKAALAHHIKTQIVFDPAVI
LRWARELKRRGIDLPVHVGVPGAVHRQKLLRVSGGLGIGESAKFLKKQQTLLWRFFVPGG
YNPAKIIKGLAPHMGKPDNTITGFHVFTFNDLEPTEEWRKQTIQALA
>E8M459|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sinaloensis DSM 21326|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDASRDELIQIADDYWNNGIQSIVALRGD
IPPGGGKPDMYASDLVQLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPSN
>A0A097ICR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium doosanense CAU 212 = DSM 45436|TrEMBL
MSVSSQAAPRLSASAPVDTQEQTDTPHPTWDRLALSFEVIPPRINQAGDRDKLDALLAEV
QTYRPDYVAVTSSARSGWLDGTAAVIEYITDNSRLRPLAHLACTAGTEEEVVRGINQLVD
AGVRGLLALRGDLPAGEQSLPSGYLQHATDLIRVIRAVEKRQAARFAAGSLAVGVACYPS
GHAEAANEDEDYDVLLAKQRLGADFAITQLFFDADDYLRFAEKARLAGVTIPLIPGIMPM
TSAARLERMGKLAGLSVPEHLRRQMAEAAENGPLAEREAGLALTAQLTRDILAGGAGGLH
VYTHNDMDVTRDLLDQVGVTPAAPHPRRA
>A0A2I1PCC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kytococcus schroeteri|TrEMBL
MTRISVELVPRSEESLLTEAASLSEVAPWADTINVPDLVKFDLRPWVGCRKVREATRRPD
GSPYGVIPHVRACDVDPDAPLPMAAEFRAAGITEVLVVSGDDADYFSQHTYPVDAVDVIR
RFRQELPGVRVYAALDPYRTGMSAELRQVERKLVAGASGVFTQPFFDVDHLRSWRRVLPD
EVEVWWGATTVTTLAALGYWRRRNLVAFPRDFRMELQAQREFAQRTIDLATEWGDNAYLM
PVRTAPAEYLAGLRVPAAA
>A0A2R6Y1Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Carbobacillus altaicus|TrEMBL
MQRVHIVVELDPPREPDLNRYLDAARRLQAAGVDAITIADNALAQSRVAALAASFLLKER
LDMPVIVHISARDRNLLAQQSTIFGLYAQGVRDLLIVSGDSMKVGDHPTGKGVFETDSLG
LMERVKRLRAGVDFFDRPLKEPVHLRFGGALNLRKQHDVMLKRLMKKYECGAEYFFSQPV
YDEESMNNIATIRDNETFPTSLPVYLGLMPIISYDNARFIQTIPGVHLSQSVVESFQSLT
GDDARQFGVQHACTLAKTAYSRYGFRHFYFVTPYLRASLTAALTVCLRTYAEEHSREKHR
PIIDQTHDKTVLINHERRPG
>A0A4Q7Y4J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus saxobsidens|TrEMBL
MTRTVRELLATERPTWSFEFFPPKSPEGEAQLWTALRELERLRPSFVSVTYGAGGSTREG
TVAVTERIAAETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQSD
WVAHPEGLQYASELVELIRSIGDFSVGVAAFPERHPRSPDFDSDVEWFVAKCRAGADFAI
TQMFFRAEDYLRLRDRVAARGCEVPVLAGVMPVTNVRQITRIVELSGQAFPEDLAERFAA
LDGDAPEARAAVRAFGVEVATDLCARLLAEGVPGIHFITMNRSTATRDVFTNLVGPDGDV
RP
>A0A1M6ACV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cruoricaptor ignavus|TrEMBL
MAGTELGGLTFKVQKSKIRGSLNEMKITEHIKKANGKTLFSVEVVPPTKGESIDDLYRNI
DPLMEFQPPFIDVTTSREEFVYLEKHGGLMERRITRMRPGTLGICAAIMYKYGVDTVPHV
LCGGFTREETEYLLVDCLYLGIENVMALRGDARKGESHFVPTDGGNANAGELVRQIDDVG
HGKFLTDEGRAWENSKFCIGVAGYPEKHIESPSMKYDLEKLKQKVDEGADYVVTQMFFDN
QKYFAFVDAARNIGITVPIIPGIKPVATKNHLSILPKTFKIDLPEDLIKAMDTAKDNAAV
REIGIEWAVAQCRELLDFGVPVLHFYSMGKSSNITKIAEQVF
>A0A382AT28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKIIDILNSKKTISFEFFPPKRDSDLPKLHETVDRLSTYNPDFVSFTYGAGGNTRQLTTQ
VSKDAKLSDKFEVMSHLTCIAHNKTEIINILKDLTLSNIENIIALRGDPPKDVTISKDNL
KHATDLIEIIKSNFSNFCIAGACYPEFHPESNNPIDDIKFTKMKQDKGVDFLITQLFFDN
KDFLSFREKAIKLGITIPIIPGILPITSTKQIRRFTKLCGAKIPLKLNEKLENSINNDQE
TTKLGIEYATNQILELIDNDIPGIHFYSLNKTSSVGHVLNNLGISNQTPEYII
>A0A3R5QW63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium manihotivorum|TrEMBL
MFIKDLFKQKRLVYSFEIFPPKLTSPIDTVYKTIEELAILNPDYISVTYGAGGSVNNNRT
CELSSLVKNKYGIEALAHLTCINSDEEKITKIVDSLNKNNVKNILALRGDVNGEQNLEDS
YKYAYQLIEYLKERGNVCLGAACYPEGHIQSDNIDKDIMHLKNKVDAGADFLISQLFFDN
SLYYNFLDKAYKKGINVPIQAGIMPVTNKKQIERIASLSGAYLPEKFIKIMDKYEYNPEA
LRDAGIAYATEQIVDLVSSGVNGIHLYTMNNPYIANKITTSISSLINHINKEAI
>A0A381VW17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MRFIRDIHAEKQGSGKPTISFEFFPFKTPEGEATFFGKTLPALITARPDYASVTYGAGGS
TREKTLEIVERIQNDFGLTTMAHLTCIKHTQAEIGGILDEAARRGIQNILALRGDPPPGE
EWAQTEGGFEFASELVEFLRERGDFGIGAAGFPEGHIDCAEGRETDWRHLVGKINCGADF
VITQMFFDNADYFRLAGYLKGQGVAVPLFPGIIPVANAGQIKKFSAMCGAKLPELFSSRL
DELGDDADAVREYGIEYATGQCRELLERGAPGLHFYTLNKSKAVLQILANLGLA
>Q058D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola subsp. Cinara cedri (strain Cc)|TrEMBL
MVTEIKNIKKLYTDKIYNLKNKIKISFEVFPPGDIFLQKKLFKSIKILNQFNPEFFSVTN
STKINSFDQTFFIVKKIRELIHCTVFAHFTTIGCNELKIEKIAHRYWNHGIKNIIALRGD
LPVLYSRKIIYAVDLIKLLNSINKFKIFVAAYPEGHPESKNIQEDLNNLRNKLDLGVKQA
ITQFFFNIDKFLKFRDTCFSLGLNVNLIPGILPILNFEQLKKFSNMTNVEVPKWILNTFH
RHKNDEKKCISCSVYIIIDLIIKLYNEGITHFHLYTLNQPHLISLICQRLGLV
>A0A5C1MAW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp. FeAm09|TrEMBL
MTILDRLTTEILTGDGAVGTMLYARGIGLDSNFEHLNLVRPALVLELAREYAAAGAQVIE
TNTFGANHTKLAAIGLGHKVGEINRAGARIAREAAGNGDKLVAGSVGPLVRMKGEEQELT
PDVMAGHFRAQCIALAEGGVDLLLLETFGSLEQLVAAVRAARETGLPVCASMAFMEGGRS
GDGTTVEAFCAAVEAAGADMLGANCGAGPLELVKVVRRLAALTAKPISAYANSGFPEYHE
GRYIYRATPDYFAAMAEEMAAAGASLIGGCCGTTPEHIAALARTLAGRRPSPRPPVSAHA
AAGVQEGSRPHRASFLDPWGRRKVITVELDPPKGMDCRRIIESSRRLKEAGVDAINLAEN
PLARPRMGNIALGSIIQREVGIEVIIHVTGRDRNLIGMQSDMMGASLLGLHTILAVTGDP
AAMGDHAGATSVFDLHSFTLIKLLTDMNRGVNAIGNPIGSGTGFTVGAAFNPNTKNMALQ
AERLRKKAANGARFAQTQPVYDPGLFLEALEQTRDCGIPLLPGIMPLVSERNAEYLHNEV
PGISVPDAIRARMKGLEKEAGAREGLAIAKEFIDATFTAAGGYYLIPPFGKCELALELID
YIHAREGERR
>A0A2E2WVH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MKIFNNKIEELLSLRNNLKFSFEFFPPKNEEMNIKLWDSITKLKSLSPDFISVTYGAGGS
TRTMTHETISRIISETDLRPASHLTCIGSSRAEIDSILRNYWDIGVRHIVALRGDIPNDS
YNHIDSKNSYKYASDLVNAIKELKKEGINFEISVAGYPEKHPEAKSLDQDIDNLKKKVDA
GADKIITQFFFDCDVFFRFRDKCHAKNINIPIIPGILPVTNFKQVSKFAKMCHTNIPKWM
SEIFNTLDNSIESKNLIAGMIAIEQCRLMMKENINNFHFYTLNRAELTQSICKIIRG
>A0A381WQ81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
VVTRNQADKAVQKRLLEGMTYELIPLKNLTDQSQHLPAGATVSVTCSPAKTVDDTLDLCA
GYAEKGFTVIPHVAARMVEDEGHVDRIVQRVNVLGIRTVFCIGGDADPRGPFTDAAGFLR
SFLDRRPNVDAVGIGSYPDGHATIPDRALADTLVEKQELIREAGLEGYMATQMCFNADTI
GDWLEGRRAAGVDLPCHLGVPGAVDRARLLAISIRLGIGHSARYLKKNKASVIRLLSPGG
YDPNKLIAPLSRRADELGISGIHCFTFNAVDTTESWRQKSLRKLGS
>A0A382R775|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
HPDAKPVFDFSTLELLDAANKLNAGIDSTGNKLNKAPVFNIGAVVNPGADNLDKEIDRLK
EKIDNGATFFQTQAIFDVSAFERFCNRVASFDLPLIAGILPVKSVKMAAYMNSNVPGINV
PASIINRISESKSVKATSTEISAAIVADIKPFCCGVHLMAIGWEALIPAILEQAAVR
>A0A381N4Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
VKITEGCFEATGHTSIICDFSPPRSGDSAVVTQAQIDADFILVAYNPGRAVRTNSAMLAA
AIQQSGKDAVFTLATRDMNKLAVQSLLLGAQLLGLQNVVVVQGDLFGEQDQARVATVNDY
HSTGLISAIVQMNQGQDFKEAELRAPSDFCIGGAVDLGRGIEEEAQLAVRKVQAGAEFLI
TQPIFNVDHVARYRESYAYHAGKAGTLPIYFGLQILEQDGVLFSSVPESVRADLEGGRSG
VDIALELYQEFQKARLNNVYLMPPIKRGGARNYEAAKEFLTLINKI
>E1WNU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis (strain 638R)|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>B4UHX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeromyxobacter sp. (strain K)|TrEMBL
MRITDLLRFARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTR
AKTIELVKRLKRDAEVEAMAHVTCVGASRDEIAAVLDEVAEAGIQNVLALRGDPPRGQGA
FVPHPDGFAHASELVAFIRSQPERWRFCVGAAAYPEGHPETRDLAQDLRHLKLKVDAGSD
FLVTQLFFENAHYFRFVERARAGGIEVPVVPGIMPFTNVEQVERFTAMCGAAIPPPLRAA
MEVRRADPESARELGVAYATLQCADLLRRGAPGIHFYTLNRSPSTRAIVAALRACEPWRG
>E7PI09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. glycinea str. race 4|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A381WB21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MHLIDLYKKKSFVFSIEIFPPKTKKGEEKLKAMLGEFKSCTPDYISVTYGAGGSSRENTH
ELAAHINNDLGVPAMAHLTCVSHSVKEIEKVLTKLKTSCIENVMALRGDPPAGTDHFVQT
KDGFQYASELIEVIKDHSEFGICAAGYPEGHVENLDKEDDKRHLHEKITAGAEFIVTQFF
LDNTYFLQWRDQLRKEGISVPLVAGILPPASWKAIKYMSDMCGVSIPNDLAQDLKKNVNN
PEVSRQIGFDHVERQIEELLSEEVDGVHLYALNHSETVKRLGSKLKDASRKSIKSLAN
>A0A6G8ADP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. HDW3|TrEMBL
MSLPISFEFFPPKTPEGAEKLRAVRAQLYAQRPQFCSVTYGAGGSTQAGTFATVREIIAE
GQQAASHFSCIGATKDSVRQQLAELKAMGVKRLVALRGDLPSGYGLGGEFHYASDLVAFI
REETGRDFHIEVAAYPEMHPQARSFEADLQAFATKVRAGADAAITQYFFNADAYSRFVDE
AQRLGADVPIVPGIMPITGATQLMRFSDACGAEIPRWIRLRLQGFGDDTASIRAFGLDVI
ARLCEQLVAAGAPGLHFYTMNQSAATLALCQRLGR
>A0A381US49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKVVDHIEKSSGKTRFTFEILPPLKGQNIKSVFDSIDPLMEFKPPFIDVTYHREEYIYKD
RGNGLLEKRIVKKRPGTVGICAAIQSKYKVDAVPHILCGGFTKEETENLLIDLDFLEINN
IVALRGDAVKSENYFKPTIDGHSYANELVSQITNLNKGIYLDEEMLNPNPTNFCTGVAGY
PEKHMEAPSIESDIHFLKKKIKAGANYVITQMFFDNKKFFSFEKMCREEGIKVPIIPGLK
PISTLKQLNTIPHRFNVDLPEPLIKEIIKCKTKDGVRQVGVEWCIEQSKELKNFNVPFL
>A0A368XCU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saliterribacillus persicus|TrEMBL
MKDLREDLNNKILIADGAMGTLLYAHGVDQCFEAFNLTNPDEVLHVHESYIQAGADVIQT
NTYGANYLKLSRYGLEDEVQKINSKAIQLAKTAANSKAYVLGTIGGISGVQKITSSRKEI
IRSFKEQLYTFLLEGVNGLLLETYYDLNELKDCLQIAREETDLPIITNVSMHEPGILENG
ITLPDAFKQLEDLGADVVGVNCRLGPHHMLESLEYVPLPKQAHLAAYPNASLPAYEDGKL
VYSSDAAYFKSCATNFQKQGVRLIGGCCGTTPEHVQALRKGVEGLSPLTEKKIKPIEQAI
HIIDKQKKDSQDTIASIAKKRHTVIVELDSPKHLQVDSFLDGVQALKDAGVDAITLADNS
LATPRVSNTAMATMIKQKGIDIKTLIHLTCRDRNLIGLQSHLMGMHTLGFDEILAITGDP
TRIGGFPGASSVFDVTSFDLTRLIKQCNEGISFAGTSLQTKTNFQVAAAFNPNVAHINKA
VKRMEKKIAQGADYFLTQPIFNKETIIELYHATKHIETPIFIGIMPLISYKNAEFLHHEV
PGMRLSDDVRDRMQQASHNRATGFRQGIAIAKELIDTAIEYFNGVYLVTPFMYYELTVEL
TDYIHEQTLKKQTQTLNS
>A0A5I8VCR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Stockholm|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1A5RRU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3873|TrEMBL
MEKAAIRPSSIYASIEMAPSQVIDSPDLPGLFPSGVRVYITDIGLADTPTLVKAARRVAD
LGYTAVPHMAARRLTTRQALETRVKALAEEAGVRDLLIIGGDVATPAGSFSSSFKVLETG
FVDKYDIAEVGVAGHPEGSRDFGDEAAIAALRMKSAWAERTGAKMRVVTQFGFDADKFIA
WADGLAVSGVDLPIHLGVAGPAKITTLLKYAALCGVGNSLNFLKKRSASLAALATSHSPE
SFVGPIEHHLRAKPESAIAQLHVFPFGGIKNTARWLYERGSWQDLEADDRSSIA
>A0A382GU69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKVTEHIDNAKDPLYSFEIIPPQRGKSAQEIIEIVKDLEPFNPPFIDVTSHSAEAYYEEG
RDGDIKRRVRKKRPGTISICGIIQNRFKIDTVAHLLCRGFTREETEDAIIELNYLGIHNI
LAVRGDETNYKKPVHSGRSANLYASDLVKQLDNLRSGIYLDEILNADAVDLCIGVGGYPE
KHFEAPNLKKDIQFIKQKVDAGADYIVTQMFFNNEDYFNFVDECRKAGITVPIIPGLKIL
NNPKQLTSIPKNFYVNIPTELSEEIEENPDYIHEIGVKWCIKQCEELLNNGVMSIHYYIM
SGAKAVTKVLKELNK
>Q6BM19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)|TrEMBL
MPTVKDRVQALKPHERFVSFEFFPPKTDTGFRNLLARLNRMSALNPLFITVTWGAGGSTS
EKSLDLAATCQKEIGLTTVLHLTCTNTNKEIIDNALEKAKEQGIRNILALRGDPPRTEEY
WIPDCDFNNAVDLVKYIKQQYGDYFCIGVAGYPEGHVDGSDSSNQDPRNDMPYLVEKVEA
GADYIITQLFFDVDKFLNYEAMIRSYPQLKDIILIPGLMPITTYKVFTRATKLSHASIPL
EIQSSLHSSSYDDDLVKNIGIDVINNIINKIDSNTDNRIKGYHFYCLNLEKAVASIINDS
DVLKSVMDLPDETNNNEDAIASDSDEDLPAVTISNRRRKSSIINDNELADKSNAQKSLVG
KALIGDKRTLVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPTLKIYSPEEA
IHKWGAPESVNEIIKVFVSYLSGKIDSLPWVDAALSPETALIQEELFEVNNKGWFSLASQ
PAVNGCLSSDKIFGWGPGNGIIYQKAFIEIFIPKDTWTNKLLPGLQKYLDDQTITYYCGD
AEGRLTSNLNIDQEHYNSKNAITWGVFPSKEVLQPTIIDLESFKAWNEEAFILWLEWARC
YKKTSKTYELLNSIYKDYYLVSLISHDFKDEYALWNILLENK
>A0A3M1VS15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MSLKLLSEIKSGHHKPFLCLEVNPPRGTDFEHIFKRLDNNVEGIDFFNITDSALARMKMA
PIPFASMLKQRYGIEPLVNLSCRDRNLIAIQGDLLAAWAMGIRSPVALTGDAVTVGDSPN
RKGVFEVNSVGLLGVIEKLNSGEDLAGNKLQGSPKFVPGVVANPNAKNVAAEVRRLVRKK
EAGACYALTQPVFDPVVAEEFLARAGECGLPIFLGFLPLKKGASALGIANIPGIRLPEDM
LKYAGKDPGRDMTDYSFKRCLEIAQASLGKVCGFHVISGATPRLALKLAGELKSFISEKS
>A0A4Q2ZA33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
TQLFFDNHDFYDFRDRCELAGIHVPVLAGIMPVTSLAGMIPARTGTWMPASSQRSRKS
>U7GBD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. COS3|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELKLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIKRFVEKVQAGANAGITQFFFNPDAYFYFI
ERLAKAGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A4P9XV04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thamnocephalis sphaerospora|TrEMBL
MKITQKIAKAEKEKRPYWSFEYFPPKTHQGLLNLYDRLERMYRLGPEFIDVTWGAGGSTS
ELTLEICATAQTVYGLETCMHLTCTCMPREKVDDALRECKENGIQNILALRGDPPHGSDT
WEACDGGFTHAVDLVRYIRQQYGDYFCIGVAGYPEGHTECESKELDMQYLKEKVEAGADY
IVTQLFYDTDLFLNWVQECRRMGIQCPILPGIMPIQNFNGFKRMTTLSQTAVPQAIYDAL
EPIKDDDQAIKDYGIQLAIEMCKKIQAAGLTGFHFYTMNLERSVRLILEGLQFVAPVEVM
RPLPWNPSKSRKREKESVRPIFWKNRARSYIQRTESWDEFPNGRWGDSSSPAFGELDGYG
ASIKQTRQDAIKLWKYPTTAEDVADLFARYCLGQLSALPWSDQPPMAETECIHDELARVN
RLGYLTINSQPAVNGAKSSDAVFGWGPKHGYVYQKAYLEFFVSADRLPQLLQNIQKDPSV
TFHAVNREGDLHSNAEAGAPIAVTWGVFPGKEIVQPTIVETASFLAWKDEAFQIWKQWAA
VYEEDSATARLLEDINATWYLVNIVYNDFQAPVTAIFSLLNDGEKAL
>A0A2E3SKJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MLDQSKKINVSFEFFPPKNDEAVMSLWSNIKRLEPLNPCFISVTYGARGSTRDNTHSLVK
EIKERTSLIPAAHLTCIGSSQEEIESIADDYWHAGIKDIVALRGDKPLQKNTGQSEDFQF
ATDLIYLLKKKFDFNIAVSAYPEKHPDSKSMEQEYDVLKKKVDLGASKAITQFFFDSKSY
IKFLDGALKRGINIPIIPGILPVTNCKKTIEFARKMNCKIPKWLLNMFEGLDSDPETRKL
VAATIVHDQCRYLMESGISDFHFYTLNRADLSYAICHILGIRTLEGRND
>X5XBI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSHC412B00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A0Q5V2Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. Leaf363|TrEMBL
MAANLAEARALLLSPLGPVARAGSNHNPVRVSFEFFPPKTDEAEANLWKAIRRLEPLSPA
FVSVTYGAGGSTRERTHRTVQRIITETTLKPAAHLTCVEASRDEVDEVIEGYKSIGVDHI
VALRGDPPGGAGIGGVYAPRADGYANATELTAAIGRVGGFDVTVGAYPERHPESPSIDHD
IDVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGIMPVSNFTGLARMCG
SCGASIPDWLRAHFEGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRADLVYA
ICRVLGVRETAQ
>A0A7X2IGA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. CAH-3|TrEMBL
MSTHNFSIEFFPPKTAEGAQKLRTTRTRLAALAPKYFSVTFGAGGSTQQGTRDTVLEIIG
EGHDAAPHLSCIGSSRASLRAILEDYRAQGIKRLVALRGDLPSGYGAMDQASSEFRHANE
LVEFVRAETGDWFHIEVAAYPEMHPQARSPQDDVQNFARKVKAGANSAITQYFYNADAYF
RFVDDAAKLGATVPVIAGIMPITNYTQLMRFSDMCGTEIPRWIRLKLASYGDDTESIRAF
GQDVVTQLCQRLLAGGAPGLHFYSLNQAGPTEAIWQQLVK
>A0A838XCI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus halotolerans|TrEMBL
MGKRDLRAYLTQHVLVGDGAMATQLYEQGVPIGVSYEELCLSNPQIIRNVHTAYYEAGAR
LIETNTFGANRDSLSRYGLESKVTRMNRAAVTLAREAVGDDAFVVGAMGSIIAGRVRTKQ
IDQFRDQFEEQATSLLHAGVDGILLETFLDVDELLLALEVIRPLTELPIIAQLATLEVGT
TRDGHSLTYAFQQIKDAGADVIGLNCRLGPAEILRSFEATVCPDDVFLSAFPNAGRLGMA
DGTLSYKSSPDYFAESALRLHEQGVTLIGGCCGTTPEHTRAIAEKLAGRKPLPRVNPPAP
IHSERFEVQAVQKRLQPSIIEEVKHHPTIIVEFDPPKDLHTEDFLQGCCALHDAGANAIT
LADNSLATVRMSNMALGAMMKRLGIEPLLHIACRDRNLIGQQSHLMGLHALGIDQVLVIT
GDPSRFGDLPGASSVYDVSSFDLIRMVKQLNQGYAFSGKQLKQHAQFIVGAAFNPHVRHL
DAAVARLEKKVEAGADYIMTQPVYDAETIVQIYESTKHIRVPIFIGIMPLTSSRNAEFLH
NEVPGIKLSPYALEQMKLFTGEAARQEGNRMAKELIDATLQYFNGIYLITPFNYYQMTVE
LTQYIRQQEQVKAGLKEVSSS
>A0A6P1F7I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. VKM Ac-2760|TrEMBL
MTDHSGTAQESHCPVVPFSFEIYPARTVAGARALERTADRLAAAGPSFVSVTYGAGGSSR
SASLEILRYLREHTTAEPLAHLTCVGSTHAEANRLVHEFLEAGVTRFLALRGDPPADAAE
GEPFLGELGSAAELVQLIHRVQAERAPYDAVTVLPNAQRVDLARRPRAQVAVAAFPNGHP
RSRSRSQDIDALLAKEAAGAAFAITQLFFHPADYLRFVERARAAGVTMPIIPGVMPVTSP
ERLRRMLELSGEDLPADLAIALDVEPDDDARTRIGVEHAAAMVRTLVDAGAPAVHLYAFN
RHEAVLGVLAESGLLPGPRPSTARPTIPTTTLTTERAS
>A0A510Y604|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinococcus halophilus|TrEMBL
MNVLKKLSSSILIGDGAMGTYLYQKGYKGSFEAMNLTSPDTVERAHREYAEAGADILQTN
TYAANRVKLEGYELEDKVLDINRAGVQLARKAAGETAYVFATVGGIKGVQVSEYSDEYLR
NALQEQVDVFLAEPVDGLLLETFYDLPELLQVVRYIRSKDAEIPVIAQVALGDVGVMHGG
VQISEAFSRLEDAGASVVGLNCRMGPYHILKSLEQAELTGKAYYSAYPNASLPNWYDGRY
VYQSNPEYFYKQAFRFKEQGVRLIGGCCGTTPEHVRMIAEAVKHDVPEKTKPPVKVEPPA
AEPPAEKEQFVPLHEKVKNENTVIVELDPPKKLKTGKFMRGSQALHDAGADAVTLADNSL
ASPRIDNLAMGAMLKQQSSARPLLHIACRDRNLIGLQSHLLGLHTIGVRDLLAITGDPSK
VGDFPGAKSVYDANSVSLISLIREMNEGRLFSGKSLGEKTNFSIGGAFNPNVLHIDKAVK
RLEKKVNAGAHYFMSQPVYDVNRIKTIHEAVKELEAPVFIGIMPLVSAGNAEFLHNEVPG
IQLTDDTRKRMAACGNDAEAAKREGIAIAKELIDETLRYFNGIYLITPFLRYEITAELTR
YVREQTEAGVTEI
>A0A7W6AGL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium brachythecii|TrEMBL
MAPSKSHRASRDGFKPIRVSIEFFPPKSDEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVKETNLKPAAHLTCVDATKEEIDGVVQSYWDAGVRHIVALRGDPQDGVG
TTYRPHPGGYAQACDLVAGIKKVGDFKVSVSAYPEVHPEAASLDADIDALKAKVDAGADQ
AITQFFFDNDVYFRYLDKVRAAGITIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLEDDVETRRLVAAAVAAEQVVDLVDAGINDFHFYSMNRSDLVYAICHILGLRGHGPKA
TDRKAA
>A0A165X8L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudovibrio sp. WM33|TrEMBL
MSEHSIDRRFRLNGASDISVSFEFFPPKSEKMEQQLWSSIKRLEPLAPNFVSVTYGAGGS
TRERTHSTVSRIVNETALKPAAHLTCVDATKEEVNEVIRAYWDAGVRHIVALRGDPAAGL
GEQYHPHEGGYQSTADLVASIRSIGDFEVSVSAYPEKHPESPSWETELDVLKAKVDAGAT
RAITQFFFDNDHYFRYVDRVRAAGITIPIIPGIVPVTSFKGISGFAKKTGASVPGWLAHR
FDGLDDDPRTRELVAAAVAAEQVMSLADDGVEDFHFYTMNKADLVYAICHMLGLRAKQDV
KASVAA
>A0A0C5X0V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. (strain YBL2)|TrEMBL
MTLSFPSVEEATRAWQAPLYADLTGDINVSFEFFPPKTEKMEEQLWSAIQTLTPLAPKFV
SVTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKAEIDGVADAYWEAGVRHIVA
LRGDPPEAGAKFEAHPDGYKGAAELVEGLVKRHPFEISVAAYPETHPDALSARGDIDNLK
RKLDAGATRAITQFFFEPDTFFRFRDTVAAAGIDADIIPGIMPVSNFAAVQRMSAMCNTD
VPGWMGKLFEGLDDLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPATLEKTA
>A0A0C5JW40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea vervacti|TrEMBL
MTQPSFSFEFFPPKTADGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQGTLDTVIEIQR
EGVDAAPHLSCVGSTRDNIRDILKTYRDNGIRHIVALRGDLPSGMGEIGEFRYASELVEF
IRAETGDWFHIEVAAYPEYHPQAKSPRLDLEHFAHKVKAGANAAITQYFFNADAYFRFID
DVSRLGVNVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VSALCERLLKEGAPGLHFYTLNAASATKAMWQRLGL
>R5WD04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus eutactus CAG:665|TrEMBL
MKIRDLITQDKATLSFEVFPPKKDTDFADVEAAALGIAALKPDYMSVTYGAGGSTKGHTI
QLAREIQEKYDVPTIAHLTCVCASRDGIKNALVEMKSAGIENILALRGDIPKNYDGQVFT
EFSHASELVELIKESGDFCVGGACYPEVHPDSANKHDDIAGLKKKVDAGCDYLTTQMFFD
NNIFFNFMYRVREAGINVPIIPGIMPITKRVQVGNAVKLSGCNVPERFKSIVDAFGDTEA
AMRQAGIAYATDQIIDLMANGVKHIHVYSMNKPEVAAGIQKNLSEILKV
>A0A858WSI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Starkeya sp. ORNL1|TrEMBL
MSSDVERRSRRTGGRPISVSFEFFPPKSEEMEATLWSSITRLAPLAPKFVSVTYGAGGST
RERTHATVERIIKETRLAPAAHLTCVAAAKGEVDEVVRGYWDAGVRHIVALRGDPPGGVG
HAYEPHPEGYATSADLVAGLRRIANFEVSVSAYPEKHPESPSFDADLDILEAKVDAGASR
AITQCFFDNDLYFRYLDKVRARGIDVPVVPGILPVSNFKQAKNFAEKTGTYMPGWLAGRF
EGLDSDPETRKLIAAAVAAEQVFDLVDRGVTEFHFYTLNRADLVYAICHLLGLRPPQAAA
GEGQAAA
>A0A109WDP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp. oral taxon 136|TrEMBL
MADIREHLKHEPLVFDGGMGTYYAQKTNTRGKGVELANLQSPDVVAGIHAEYLHAGAQAI
KTNTFAANRIVYQGDDELVAQIIRAGWALAARAAEPFGAYVFADIGPVIGLPPRDIAAEY
RFLADTFLSCGATHFLFETNSSAEGLTETAAYIKAACPHAFVQISFTALPGGYTRDGFFA
EDLVRAVAESGQVDAVGFNCVNGVRQMKELLHHLKSVSLPLALMPNAGHPMVVDGRTFYE
SAPEYFAETLAALVQDGVSILGGCCGTTPVHIRALCTALGTQGTVTADVQAAAEQEPVIQ
AESPFFAALRDGRKVIAVELDPPETGHAEKFLRGARELREAGVDAITIADNPVARARMDA
AMLAARVHRELGIEPIPHMTCRDRNLNAIKSILLGLSAEGIHNMIAITGDPIPTAERDEV
KSVYQFNSRKLSAFIKSLGEHGDVLPFHVFGALNINAKHFPSQIGLAKKKLEAGMTGFFT
QPVLSERAKENLRTAREELGDALIMGGLMPVVSERNARFMESEIAGIHVEERIINAYHGL
DREAAEELAVRLSLEIAHDIEPYIDGYYIITPFSRTPLVARIVAELLK
>A0A3D5FNA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MSSTCTRPLIRIAESLHCHIPSVRASAQRWLTGDHIDRHAGDKHLRKLVTDQVQAGADFL
DVNVDDFFTVEGIGHDGARQVLAHILHLIAEYGHGVPPCIDSSDPSILEYGLQVDREGRG
ARGGRMPLVNSVTINRLEALQLRSGLPFAVVGMLLEKAGDDGATGFTDIADAAIYHETAK
QIFDAARDAGFSAQDVFFDPTVGPLGADMVGYTKRTFEGIRMIREDAGMAGAHVVLGLSN
CSDGLPRRLAINRAYLRVAMEYGVDAAICDVGQISGKDLVDGRVLKLIRKIATGDAEAGA
TDALILLVDYAQSQRRAPAAPSRSTKFDDPFGRALDDPTGEPVFILELAPSEGGLDQIFD
VAEKARDEDYIFTITDTPGGNRTPGPDTLALEVARLSGRQPIMNLSCKSDDRNALIRRAL
ALYHQGLHHFFAVTGDYTNGGRPVFDLDAVSLAMALDSLRRGLEFPDLLPRAGGALDQLR
IGSAVSPFKYDEADSWGQYLKVWKKRRAGADYLITQLGYDVAKFQELKIWMSRAGMSDTP
VFPMVYFLTPQFLRVLNRVHVAGAVIPDELKRKYQGRLGSKQEVKELRALNFSDLASHQH
RQAVRRAALLSHILLDGFRFRGIDLAGITQLDDARAVRDELASLAGCDWHASWEEYRDAD
GTRPMQLSPSEDAFYLFEQREDGLLQEDSPLLRGDRSAYQPIDPQMKRLHGRYFEPGRGL
NGLLQWMVGGAPDGSRLKWATLLEQATKRSKLGCEMCGDCRIADLAYLCPEPTTGCAKRL
LNGPCAGADLQGGCEVTPERRCYWGRVLEATLADGGVEGLLALQPPKDPSLSHTSSWRNE
VEGRCPQSLDLGLPPSEALPPR
>A0A3Q2Q4A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fundulus heteroclitus|TrEMBL
MVNQVQQVEGCWQSTKGESSGASNSSGESSKEGSRCSTPVLDADRSDRLQEKMRKRIASG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTRERITGYLAKAKHLGLKNIMALRGDPVGDDWEEEEGGFSYAI
DLVKHIRSEFDEYFDICVAGYPTGHPEAESYQQDLWHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIHQAVEMSRVLLDSGKVPGLHFYTLNREVATVEVLRQLGLWIEDPRRPLPWAVSANPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKET
LLQMWGEELKNEESVFEVFTCYIAAKPNRNGQKVMCLPWNDEPLAPETNFLKDELEKVNR
CGVLTINSQPNINGKPSTDPVVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGHNMTNAHELQPNAVTWGIFPGREIVQPTVVDPVSFMYWKREETGDGEQRIG
EPTQGASSSTDSNRHPRSRESPTQRKGPSQLHHHSPGARERPQGPPANHPPGPTPPTQMP
KFKRFLHLMSNPGHSTIVLIQ
>A0A1M6AS27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus bendigoensis DSM 12906|TrEMBL
MLHPDSRSGTVAELLGSAQGPLFSFEFFPPRSEEDEPILWRAVDALSPLAPDFVSVTYGA
NGSRRDRTIRATRRIAASGGPLTVGHLTCVDQSKAEIAAALDAYREVGVTNILAIRGDMP
GGGDWVPHPDGLRNATHLVRFIKEQGDFCVGVAAFPNPHEANNDPELDAAILEDKVEAGA
QFAISQLFFDAERYAELLDRMHGRGCHVPIIPGIMPLTVITQIERFADLSGRPLPADFVA
RLRAAGSKEEVREIGLGAALQMCRDLLAAGAPGLQFFTQNRSKATREVLAQLKDEMEAEA
TQSSRPRH
>A0A1I5LF64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania nanhaisediminis|TrEMBL
MSPTLDQMREAQRALETPLFSGLPGDIDVSFEFFPPKSDKMAQTLWESVETLAPLSPRFV
SVTYGAGGSTRERTHAAVRRIVNETSMPAAAHLTCVNATREEVDAVAREYWDEGVRHIVA
LRGDPPEGGTAYTPHPGGYANAVELIAGLKRIADFEISVAAYPEVHPDSPDRQADLDNLK
RKFDAGATRAITQFFFEPECFFDFRDKAVAAGIEGEIVPGIMPVLSFGAVQRMSGLCGTG
IPEWMEGLFAGLDEKPDARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRPKA
>A0A511KMM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosporidium toruloides|TrEMBL
MTTTPELRSSHPSTRVVDRIAQSDPSKPFYTFEVFPPKTDAGLVNLLDRIDRMSALNPAW
MHVTWGAGGSTQERSLQLAGESQSMGLETCLHLTCTNLEEGVLDRTLKRAKELGVVNLLA
LRGDPPRGEEYWTASSDKFQHATDLIKYIRKEYGNDFCIGVAGYPEGHADSADKLADIEY
LYEKQQAGADFVVTQLFYDVGVFMEWYRTCRKRGITIPIIPGIMPIQNYLSFRRMTNLCG
THIPPEILDDLQRIQHDDAAVKEYGVQLAVKMMRELFENDIRGFHLCTLNLEKSVTRVLE
LLQWAEPGSTKISSRLRKGLSPNGAPLPKVINSLRPAPSTGVNVAGPDIARKDSPASWDE
FPNGRFGDARSPAYGEMDGYGVSLKLPPGEAMRQWGEPTTLSDVSRVFSSYLRGSLPSNP
WSEEPLRAETEMISSHLIEMNDKRHWWTVGSQPAVDGAPSADPVHGFGPKGGYVYQKAFV
EFFLTREELDELERKSDEDERRRRASGEGDDGLIKWFAGNAKGDFRCNMGKGDVNAVTWG
VFGAKEIVTTTLIEEMSFRAWCEEAFALWNEWSLLYPANSPSRTFIRSLADCRWLVSVVH
HDYKEKDALWKWLLALKRPEEAHAATNGEAEGR
>W1N6J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas huangheensis|TrEMBL
MIRFHAADSCDEEHAMSAQEHPLGISFEFFPPNTDAGREKLMHTRDMLAERNPRFFSVTY
GAGGSTQNRTIDTVNAVRQCGISTAPHLSCVGSEKAQLRDLLHSYRDQGIDNLVALRGDL
PSGMGGVGELRYANELVEFIREETGNHFQVAVAAYPESHPQAPGFEADLQNFARKVNAGA
DLAITQYFFNADSYFHFVERARQLGVETPIVPGIMPITNYSKLARFSDACGAEIPRWIRK
QLEAYGDDSESIAAFGEEVISRLCQRLLDGGAPGLHFYTLNQAAPTLKVVDNICSTR
>A0A1S7TJ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium deltaense NCPPB 1641|TrEMBL
MLRSETARQNGDIRLSFEFFPPKNPEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLATAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYK
PHPEGYENAAALVKGLREIADFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A5F2DTC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira licerasiae|TrEMBL
MKKILEIYKTAKAPVYSFEFFPPKTPEGETKLFEAVEELSKVDPGYITVTYGAGGSTRDK
TIRITSELAKKFSLPAAAHFTCVGGNKDEIRVILKQIRESGIENLMALRGDPPKGEDAFK
KVEGGFGYASELISFIKAEGFDFCMGAACYPEKHPEAASLESDVENLKRKVDAGASYLVS
QLFFKNSNFESFLDLIRKKGIDVPVIPGIMPITSFSQIERFRAMAACEFPEKLVSDLEEV
KDRPEEFYKRSIHFSVNQCRELVKMGAPGIHLYTLNQSPASLDIVRELKS
>A0A2N9P7Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium columnare|TrEMBL
MKVTEHIEKANGKTQFSFEILPPLKGQNIQCIFDGIDPLMEFNPPFIDVTYHREEYEFKE
LSNGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKAEKEGNAYASELVTQISNLNKGIYLDDDLQNTNATDFCIGVAGY
PEKHMEAPSMDSDIYFMKQKIKNGADYIITQMFFDNQKFFEYVEKCRNAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNEAVKQIGIEWCIQQSKELVKSGVPFLH
YYSMGKAENIKAIAGEVF
>A0A6I9SUZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sesamum indicum|TrEMBL
MKVIEKIREATAANDSRAVFSFEFFPPKTEDGVDNLFERMERMVAHNPSFCDITWGAGGS
TADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQ
DKFVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEGHPDVIQDGVAPPEAYQNDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITVPIVPGIMPINNFKGFLRMTGFCKT
KIPPEIMAALEPIKDNEEAVRAYGIHLGTEMCKKIMASGIRTLHLYTLNMEKSALAILMN
LGLVEESKIARPLPWRRPANVFRVKENVRPIFWANRPKSYISRTVGWDQYPHGRWGDSRN
ASYGALSDYQFLRPRSRDKKLHEEWAVPLKNVEDIYEKFMKFCLGKLRTSPWTELDGLQP
ETKIITEQLGNINLKGFLTINSQPAVNGAKSDSPSVGWGGPGGYVYQKAYLEFFCSPEKL
NALVDKCKIFQSLTYMAVNKEGTWKSNINNTDVNAVTWGVFPAKEIIQPTVVDPQSFMVW
KDEAFEIWSRGWAKLYPEDDPSRKLLEEVQSKYYLVSLVDNDYVHGDLFAVFKDI
>A0A7C3ZDE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MKIIDILSRKKTLSFEFFPPKTEDDFGLFINTIKELKKYNPDFISVTDSQISAKMKHIAL
SKFIKEKLNLNPLVHLTCINNTKKEIANSIRAIEESGIFNILALRGDKRNFSSISNDFKY
ATDLIERIPKDKFSIGIAAHPQGHPEGNLKKDIIYLKKKKELGADFAITQIFFDNETFFR
FRDRFKKEVNIPLLCGIMAITSANMFENIIKKTGDIKIPSRLLKVINSKMEGNDFIKYSI
EFTSNQISELLKNNIDGIHFFTFNRNIVLKKILENIL
>A0A662HW59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoprotei archaeon|TrEMBL
MIITEQKPFDKIKSMLEKFNKVFIIGCGECATLCQTGGEDQVKEMKEKLKGLGKEVTGTA
VPKTTCDKRILRRDLKKFKEAIEAAQAILVMACGNGVQAVAEFTSKLVVPALNTLFMGEI
ERIGRFYERCRACGDCVLFETGGVCPLTQCAKGLLNGPCGGYANGKCEVGGWVKDCAWVK
IFNALKEQGRLDLFLKFRPPKDHRKWFASGPRELVWKERKEAKAEEREVWIPGERWPPKE
TYSELMKKLKDGEFVITGEVEPVKTTRVDKVLEVCRTIKDYVVAVNVTDNPTAFAYLNTL
TTCYYIEKEVGLETIYQITVRDRNRLAITSDLLAAGLLGIKNVLALSGDFISVGDNPQAK
PVYDIDSTQLVWLVRKIVDKGEDIAGNKIDHPPKLHVGIAANPNAEPLEPELYKVLRKQK
VGAEFIQTQCVYDIEVLKKFLDEARSIGIKLPVLVGVTPFKSLKMMEWMVKFVPGIKVPE
EMQERLRKARERGKEAFREENLEIFGELCKEIKKTPGVAGIHMMAVGFEEIIPSLLKRAG
LA
>A0A662G279|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoprotei archaeon|TrEMBL
MGTYLYSRGVPIGSSTMEINLSNPSLIRKIHEEYINAGVDIIKTNTWSANYSKLSQYNLE
NKVYEINFRAAEIAKEASKGRVLIAASIGPLSKTVEPLGGMKRNIAYQIFREQLIPLLDA
GVDLILLETFQNLDELLLALKVAKEMSNIPVIPQMTFPNGFSTIYGYSVMDFAKTLENEE
VFAIGVNCGLGPWHLLKSIEILRSYTSHHISAQPNAGVPKFLGDTLYYPTDPLHFSEYGI
HYYRLGVRILGGCCGTTPKHIAELYSKLSMKRPKEMVIPKLKPEVEIKKWTPTLLQSSLK
KFFTILVEVDPPRRLSLSKIFRALMKLRAAGVDAINIGDNPLAKPRINSIVFAHLVMENL
GLETVAHFRCRDKNLLAIISDLKSAHILGVRNIVVLTGDPISIGEYPHVTPVMDIGATGV
IKLMSMMNRGQMPDGSLLGESTSFYIGSVVNPNAKNLMKEIRLLKKKVKFGARYVLTQPI
FQTEKLKRFIKKADLNIHYITGIILLKNEKHAIFLNDEVPGIEIPDEIITKLEEGYSGME
IAKEVLSKLLGIAQGAYIIPPARNISLAGELVEYVKSITKRL
>A0A7K2VU17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID1328|TrEMBL
MERVLGVSGRAGELLDGVSLEMTGKDVPRLEEARASLDGGTRINVTYLAGEDAGMRLAAA
RAVREHGFVPVPHLSARRLPSSAELERFLAGLAEAGAVDNVFVVGGDPARPEGPYEDALS
VIRGGLLQRYGVRHVGICGYPEGHPAIGDGALWSALTGKAAAIAEAGLSGDVITQFGFDA
EAVLTWLEALRGRGVHLPVRVGVPGPAGVRRLLGYAARFGVGTGASVARKYGLSLTNLMS
TAGPDRFLDDLAGGYDPSRHGAVKLHFYTFGGLRTTAEWITRYRRERG
>A0A7X9A3M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MYIKDLFKRKPVISLEVFPPKPDAPLDNVLKVIEEVQDLKPDFISVTYGAGGNSRAYTVE
IANLVKNKYNIEALAHLTCISSTKKDILNLVEQLKEKNIKNILALRGDLPQNQDENPTII
DYQYAQDLIKDLQTMGEICLGAACYPEGHLESPSLNQDLKNLKAKVDSGVDFLITQLFFD
NQLFYNFLEKTDISGISCPISAGIMPVINKKQIERITNLCGATLTPKFKKVLEKYEHKPE
ALKEAGIFYATEQIIDLLANGVDGIHLYGMNRPEVVKQIFTNIDTIRSSAYEN
>A0A7W1QUB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MKLRDLYARPGVTLSVEFYPPKSDQGDEDLLREALILKSLHPFYCSMTYGAGGTTREKSV
DLVTRIQRECALTTMCHLTVTGQSKAEVRGVLEKLKTNGIENIIALAGDPPQGAAAEWVP
HPDGFHYSIGLVREAVAHGRFSIAVAGFPEVHPRAGSRAADLRYLKEKVDAGADVVITQL
FFDNDDYYRYVDDARKLGIRVPIAPGLLPIQSVAQARRITALCGSKIPPRLEALLAAAGD
DNEKAVQLGIDYTTQQCEGLLRFGVPGIHFYSLNKSRSVKAVFENLSFSAAK
>A0A662HUN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoprotei archaeon|TrEMBL
MVDEGVDLTGNRVEGEVKFNVGIAGNPNAEPLELELLKIERKVRLGVDFIQTQCVFDIEL
AKNFLKEIKKFNTPVLMGICPIKSIGMMKWYIEKCPGGIKIPREIQKRLVEARRQRGKEA
VLEESIRISAELIKELRKTTNAAGAHIMAIGFEYVIPKIVKYSQT
>A0A2T0TQT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus tzadiensis|TrEMBL
MKRALSVRDRATRETLRRAFGDLGYEVIPFKKTEQAVLEHVPRDVRLTVTASPAKGQDAT
IDLAVALVGHGYTVAPHLSAQQVRDRAHLADVVARCREAGITDVFVVGGDPTDDPTEFAH
AHDLLVALHELDHGFTDIGIGGHPEGHPTASTETLFQALKDKAPLATHITTQIVFDPEVI
LTWARELRNRGIDLPVHVGVPGAVHRQKLLRVSGGLGIGESAKFLKKQQSLFWRFFVPGG
YSPNRIIRELAPHIGKPDNGLAGFHVFTFNDLGPTETWRQQMLRDVA
>A0A2T0TY83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus tzadiensis|TrEMBL
MTPSVRELLASSRPTWSFEFFPPKSPEGEAQLWTALRQLERLQPSFVSVTYGAGGSTREG
TVAVTERIAAETTMTPLAHLTAVDHSVAELRHVVSRVAAAGVRNLLALRGDPPGADPQAE
WVRHPEGLEYASELVELIRSMGDFSVGVAAFPERHPRSPDFDTDVEMFVRKCRAGADFAI
TQMFFRVEDYLRLRDRVAAHGCDVPVIAGVMPVTNARQITRIVQLSGQAFPEELAARFAE
LDGESPEQRAAVRAYGVEVATAMCRRLLDEGVPGIHFITMNRSTATREVFTNLTGAGTSV
PSTLAVG
>A0A3B7DMI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. THN1|TrEMBL
MAAPLIHPNWDKAPDGITDGFSLEMTAKDEASLRDAAPLIPADTPIAVTFLPGEDVAARV
AATVAVRQLGFEPMPHFSARRITSEDDFEGYLRAVVEQAGVTRCFIVAGDPPEPVGPYFD
TSALIATGAFERSGIKAIGIGGHPEGHPNMTEAECWAVLEKKVAEITARGMAPLIVTQFG
FDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVTN
LLGTAGPDKLVDAFARGLGAEHGKVRLHFYPFGGLTKTLEWIHGYNKKHGIGPGA
>A0A3C1F0M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MKLSELFEQKKFVVTSEIGPPKGFHLEKILHEAEMLKGRVSAINVTDNQSSVMRFGSLAT
CHFLKDKNIEPVYQVVCRDRNRIALQSDILSAAAFGIENLLLLTGDHTKLGDHPQAKSVF
DLDSVSLIHTVKKLEEGVDIAGNKLDGEPPRFCIGAVVSPCSEPLEPQLIKMEKKVKAGA
QFFQTQAVYEVDKFVKFIEKAKQFGVPIMAGIVILKTVGMAKYMNENVAGIHVPDSLIEE
LKKDKEKTKSGQTGIEIAARLIKELKPHCEGIHLMPLGWDDKVSKILDMAGL
>A0A537DVW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
PSLPGLPVSRVLETVAAIRQAGLDPVPHLAARRSAGREPLREFLRRAAGEHGVHRVLLVG
GDQPRASGPYSDTLQVLEEGVLADTGIREIGIAGYPEGHPRIAPAALEEAFARKQRLAAE
QGLGVYVVTQFCFAPARVVEYCAALARSAPSVSIYVGVAGPTDPAALLRYAQRCGVSVSL
RALRNLGTGIAQLVTHTDPHEQVVALARYSRSRAPSNVIGVHLYSFGGAVRTATWMRERI
AG
>A0A1H3WGL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas ruminantium|TrEMBL
MKRVSVELIPRDEETLRGELQLLKQYEGKIDVINIPDLLRFDTRSWEGSAIAQEYFAMSM
PHIRAMDIDLDKELPMKDYLREKGIKEVLVVQGDPPQRMTHEVYPTESTDVIRKFREEMP
EVKVYAGIDQYRSSMRHELYRTRRKVQAGAAGFFTQPFFDMRLLSIYMDMLDGLDVYWGV
SPVVTAASQSYWERKNNVIFPKHFAPTLEWSVDFSRQVMEMADKKDANVYLMPIKTNLEE
YLAGVLA
>B9KC45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E)|TrEMBL
MRKSLESGKCVVLEVLTPRGTNLKKFLDFTEKAWETGIDAFTVTDMPMGRVRMAPWAVSH
LLVESGKEVLMHFTRNTRNMIRIQSDLLGCHALGIENLLLLSGDDPSHGDYPQTTSVNDV
DILDLIRLTKLLNEGTDLAGNRMYGKTNFFVGGALNPFSEKDLERAKQKIEAGVDFLVTQ
PLFQRDVAQKIKEKLSTKILVSIAFFENAKQMNHFSGVPGIEIPKEIIESAEKGDEHVKE
RSFEAVLRFVEETRNIVDGFYIVAVVKDLEKIRMVVEVAKG
>A0A0C9ZYJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pisolithus microcarpus 441|TrEMBL
MKLSDKIAAHPTHPFYTFEFFPPRTDQGFDNLLTRISRLSTLDPIAISVTWGAGGSTKDG
SLDLAGITQADYGIDTILHLTCTNMVPGLVDDVLRIAKARGIQNILALRGDPPRGQEHWT
PIDSRFSRGVDLVKYIRSSPEFSPHFCIGVAAYPEGHPDNQTDDDRNFAILKEKVEAGAD
FIVTQLFYDADRFLLWLERVRRQGISVPIIPGVMPIQTHSSFLRVVSLCGIQVPPSIMTD
LEPIRHDDQLVKEYGIRLAVDIIHKITGNGGVCGVHFCTLNLEKSVQLVLERLRWVGGSP
NIRNKLIADSPVPLLPNSELVVTPATATTKAAAALTSKTTAEIEPPGQGELNNAATWDDF
PNGRFGDYKSPAFGIQDQWGGLALSVHAVHPDWGHPASMEELTNLFLRYLDSKVTSTPFS
SSPLSAESQTILHQLKALTRNGLWTVCSQPAVDTLPSTDEIFGWGPRGGYVSQKAFIEFF
STEEVVDKIEKKIRSNEGRSVHYFAANLQGCFKSNVQEEARNAVTWGVFPGKEIVQTTII
ERESFLAWKEEAFSIWAEWASFYPPGSAQRATLEEVRRTRWLVNVLHHDFKDPGALWNFL
ADFYS
>A0A1M7IFS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salegentibacter salegens|TrEMBL
MKVSEHINRAKGETLFSFEIVPPQKGRNIQDLYNNIDPLMEFKPPFIDVTTSREEHVYIK
KEDGLLERKITRMRPGTVGICAAIKQKYNVDTIPHVLCGGFTREETEYLLVDCHYLGIEN
VMALRGDAMKHQRYFEPTHGGNCFASELVAQIKDLGEGKYLNEVIESDNNADFCIGVAGY
PEKHLESPSLQTDLKRLKTKIDAGADYVVTQMFFNNKAYFDFVDQAREAGITVPIIPGIK
PIAVKRHLQLLPQVFSIDMPEELIRNVESCKNNAEVRKVGIEWAIAQSKELKAAGVPVLH
YYSMGRSTNIQKIAEAVF
>Q5K8Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)|TrEMBL
MKITEKLQKAEKEGRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALREAKSHGCQNILALRGDPVAGTST
WEPTPGGFMNAVDLVRYIHEHYPGDFCVAVAGFPQGHPETPDTPEGRAQEMEWLKAKVDA
GAEFIFTQMFYDTSIFFDWVKRVREAGINVPIIPGIMPIQNWEKFEKWVQRENIIVPSHF
YEALNPVRGDDEKVRQVGTKLVADMCKTILDNKEAGIKGLHIYTLNLEKGARMLLRELGF
EGRREQIAPLPWRPSLTPSRREETIRPIFWANRTRSYLSRTADWDEFPNGRWGDSRSPAY
GDLDGYPVSIGITAPDAYNLWGHPTTSSDLHALFARFCRGDLAKLPWSTQPPASETSLII
EQLAKMNELGYLTINSQPAVDGVRSDDKVHGWGPPGGYVYQKAYLEFFVSPDLLSPLIRR
IEKDPRITYYAVNKQGDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWAHLYPAESPSRKLITDTMNTSYLVNIVANDFRDGMSIFEPFLLDQTTVRKVVEGV
KGTVEGIVEGVKGVVGA
>W4UZG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides reticulotermitis JCM 10512|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLYQKNRLRRRPGTVAVAAAIQNKYNITIVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHETVFTPEGDGYHHAIELQEQINKFNKGVFVDGSEMKVTSTPFSCGVACYP
EKHEEAPNMDSDIYWLKKKVEAGAEYAVTQMFYDNKKYFEFVERAKAAGIQIPIIPGVKP
FKKLSQLSMIPKTFKVDLPEDLVQEALKCKNDEDAEQVGIEWCTNQCKELMAHGVPSIHF
YSIGAVDSIKEVAKVIY
>A0A537CM78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MASNLLTRLQSGDFVVTAEITPPVSTDPAEFISRALPLKGLATAVNVTDGAGAKVHLSSL
AAAHFLVQNGIEPIFQMTCRDRNRLALQGDLLGAVSLGIRNVLCLAGDDPKLGDQPEAKA
VFDLDSRGLLAMAHRMRAEQRLPSGTQVKGGVKLVLGAADMPIDPPPHWEPKALRAKLEA
GADFVQTQFCMDVAVARRYARRLLDHGVAQRLPILIGVAPIPSAHSARWMREKLYGTLIT
DAQVARLEKARDPKAEGNRICIEVLQQLAEVPGVAGAHVMAPQNFTEIPVVIAESGVTGK
KRCLT
>A0A537A463|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
TAELSPPVSTDPAEFIDHALALRGLVTAINVTDGAGSRAHMSSLAAAHFLVRSGVEPVLQ
ITCRDRNRIALQAELLGAAALGIRNILALRGDDPKLGDQPDTKPVFDLDTTALLATAQQM
RSEHRLPSGTEIKGAVKFVLGAAELPVDPPAGWRPNGLVSKMEAGAEFIQTQFCMDPDAV
RRYAARLLELGVAQKLPILIGIAPIPSARSARWMKEKLFGAMIPDRLVERLERAADPKAE
GRRICVELLQQLVETPGVAGAHVMAPAFHSAIGPVIEASRVAGAKRAGARRG
>A0A652L0W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ms191|TrEMBL
MALGTASTRSDRARTVRDILASGKCSYSFEFFAPRTEKGERSLWKALRHVEQVGPSFVSV
TYGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSVAELRNVLGQYADAGIRNMLALR
GDPPGDPLGTWVEHPEGVLYAADLVRLIKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVD
KCRAGADYAITQMFFDPESYLRMRDSVEKAGCETPIIPEVMPVVNARTLDRLPQLSNAVF
PGDVKERILAVKDDPTAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSAATLEIYENLG
LHEQS
>A0A6B5HQU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGIRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A1H8XYD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionispora vibrioides|TrEMBL
MYHLFKEYLQKHSVLADGAMGTYYAALTGRDTAFSELANLTEPAQIQAIYCQYIEAGARL
IRTNTFSANSFSLQLPQEEVKEIIKAGYHIARQAAAGKNVWVAADIGPVPEIISGTAEGD
RSRILAEYLFLADTFLAEGVDLFVFETFSSTDYLAEVAAHIKRQRPEAFIWAQFATTPDG
FTRRGISNERIVREVKQIAAIDAYGFNCGVGPTHLYNALKNLTGRDRGDIVSVLPNAGYP
EIVNERTVYAQNPDYFAEVMEQISALGVRILGGCCGTTPEHIRKTAQRLNQSAVSPVEDR
PVTVREVLPVKAAPNQLRDKLSHGEFVVAVELDPPFDTSVDKILHNAHLCRQAGVDLITV
ADSPMAKARVDSVMLAAKIQREAGIATMPHICCRDKNVNALKSSLLAGHIENLRNVLAVT
GDAIASADKNEIKSVFNRTSLSFMELIAEMNCELFKDDPFYVGGALNLNVANKRVELGRM
AKKAERGAAFFLTQPIFVDEVIDFLPEVKRAGATKILGGIMPLVSYRNAMFLNNEIPGIS
IPEEHIRRFDPAMDRAQAEAVGIQLAVELARKIKPFVDGFYFITPFNRVDMVLNILRQVM
>R9LGU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus barengoltzii G22|TrEMBL
MKPDLRATLEREVIVGDGAMGTYLYQLGFPVGISYEEFNLLRPDVIGDIHRRYLDAGARL
LETNTFSANYYKLSKFGLEAKVEDINRAAVRIAKQAAGERAYVAGAVGSIRGGKRANVTD
QELGKYFEQQIAALLSEGVDALLFETFYDLGEMRIALGQARKLTDVPVICQFAVDQIGRT
LDGFTIPDAFGAVVEEGANVVGFNCHSGPKGIMGVMDDVEGPLNVPMSVFPNAGLADYID
GEYVYGATPDYFGKCARAFADLGARLIGGCCGTTPEHIAAMAKALEGYAAQPLAKEQKLP
KPQLSASLSINEQSNAVPVASSDKEAVSGGGENRKLPSLTELVKERHTVIVELDPPRDLD
IAKFMEGAAALKEAGIDALTLADNSLAVTRMSNMALGHLVQSQLGVRPLVHIACRDRNLI
GTQSHMMGFDALGIDHVLAVTGDPARFGDLPGASSVYDLTSFEIIRMIKQLNEGISFSGK
PLKQKAKFVVGAAFNPNVKHLHKAVERLEKKIASGADYIMTQPVYDPELIVAIKQATAHL
DVPIFIGIMPLASGKNAEYLHNEVPGIQLSDEVRKRMEGLQGEEGRAMGVEIAKELLDTA
MEHFNGIYLMTPFMFYEMNVALTNYIREKSKRGSAHLSRLS
>A0A173W932|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus eutactus|TrEMBL
MNILESLKDKLLVADGAFGTCYVGMYGEQGTVAPELANMRHPERVLEIHKEYVKAGAGLI
RTNTFAANTASLDADMDYVISNVRAAVKLAKQAADGEAGTDHKKVYIAGDIGPIPADAGL
TLNERVSQYKLLGEAMQDMGVDIIWFETFPEFNVLEPVVKHLKARKDTPVMVSFCVNQFG
YSNCGFSARALLSQVAGNQYVDCVGFNCGVGPYHMLQLLKKLDIDCGKPVSVMPNAGYPK
FTQSRLVFNDNKEGFIDKIQDIAALGADIIGGCCGTNPEYIHQIMERVKTGDIAKAAKVH
VEKVQADSAVKDNFLKGRLERGGAATKNADGHKHKLIAVELAPPVDVNDQKLLDAAHILK
QSHVDVVTFPDSPSGRTRADSILMAEKVHKETGLRVMPHLCCRDKNAIAIRGSVLGAQLN
GIKDFLVITGDPVPVMFRQTTRSVFNFDSVGMMKLLQSMNEEVFSGDKITYGGAINQNRL
NTKFEIDRIKRKMEAGAEFFLTQPVFSREQAQILRDMKAETGATILVGIMPLVSRRNALF
MKNEMAGIEIPDEIIERYSGNATRQEGEECGIQIARDILEYTSDFADGYYFSFPFNRVHM
LAHIVD
>A0A841GJT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolumonas osonensis|TrEMBL
MSFDSARQVEALNQNLAELSGDINVSFEFFPPTTESMEQTLWNSIERLSKLQPKFVSVTY
GANSGTRDRTHSIIKDIKERTGLVAAPHLTCVDATPDELRAIAKDYWDNGIRNIVALRGD
LPPGADKPAMYADGLVSLLKSVADFDISVAAYPEVHPEAKSAQADLLHLKRKIDNGANRA
ITQFFFDVESYLRFRDRCAAIGIEAEIVPGILPVSNYKTLVKFAGFTNVKIPQWLHQRFE
GIADDDQTTRNLVGASVAIDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGVRPKA
>T5JYF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum EGD-AQ4|TrEMBL
MNLRQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHQSYIQAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVRIAVTAREHADHPVYILGTIGGLAGDTDATVQR
ATQAEIAANVTEQLTALLATEQLDGILLETYYDLSELLAALKIVKGHTDLPVITNVSMLA
AGVLRNGTSFTDAIVQLHAAGADVIGTNCRLGPYYLAQSFKNLAIPAEVKLAVYPNSGLP
GTDQDGAIVYDGEPSYFEEYAERFRQLGLSIIGGCCGTTPLHTAATVRGLSSRNLVPHNA
PSHVAQAPTLVTTKSQHRFLHKVATKKTVLVELDPPRDFDTRKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTAIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAV
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TNVSTKSISRKLSYGCDYIITQPVYDLANVDALADALAADQIDVPVFVGVMPLVSRRNAE
FLHHEVHGIRLPKSVLERMQQAELDGNERAVGITIAKELIDGICARFNGVHIVTPFNRFK
TVLELVNYVQQKNLTKVQ
>A0A674NYT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Takifugu rubripes|TrEMBL
ASSVCATYGQKFPCAPSNSSGESSKESSRCSTPVLDADRSDRLRDKMRRRIESGDHWFSL
EFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGL
ESILHLTCCNQTKDKITGYLGKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAVDLVKHI
RSEFDDYFDICVAGYPTGHPEAESYQQDLRHLKEKVDAGADFVITQLFFRAETFLKFLDD
CRTIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITSILEPIKDNDAAIRNYGIQLA
VEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWTEDPRRPLPWAVSAHPKRKVEDV
RPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWG
EELLSEESVFEVFTFYITAQSNRCGQKVLCLPWNDEPLAQETNLLKDELEKVNRRGVLTI
NSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVN
VHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLYEDE
SPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDSPAAPPCEDATP
>A6UYP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa (strain PA7)|TrEMBL
MSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDRTLHTVLQL
DGEVKVPTAPHLSCVGDSKAELRELLGQYRAAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRAETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQYFFNADAYF
YFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSRSIQAF
GEQVISEMCERLLQGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A177JVI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium yanoikuyae|TrEMBL
MTQTARARHDAEGPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFVSVTY
GAGGSTRERTHNTVARIARETPLAAAAHLTCVAASKAEIDEVADAYWEAGVRHIVALRGD
PPEAGTAFQPHPDGYKGAAELVEGLRKRHDFEISVAAYPETHPDALSAQSDIDNLKRKID
AGATRAITQFFFEADTFFRFRDTVAVAGIDADVIPGIMPVSNFAAVQRMSAMCNTDVPAW
MGRLFDGLDQHPAARQLVSATLAAELCRNLYMGGVRDFHFYTLNRAELSYAICHLLGLRP
QVAVDA
>A0A2W5PEI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax paradoxus|TrEMBL
AYFRFVDDARRLGIDVPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASI
KAFGLEVVTRLVEQLQAGGAPSIHFYTMNQAAATLGVLQGLGWRA
>A0A137SD81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moritella sp. JT01|TrEMBL
MSFHNAQNIEVLNQSVSELGRDINVSFEFFPPNSEAMTSTLWESINRLKALNPKFVSVTY
GANSGTRDRTHDIIKQIKHETGLIAAPHLTCIDANRQELKQIATDYWDNGIRNIVALRGD
LPPGLNKPAMYAADLVGLLKEVNDFDISVAAYPEVHPEAKNAQADLLALKDKIDAGADRA
ISQFFFDTESFLRFRDRCAAVGIDKEIVPGILPVSNYRTLCKFSKLTNVKVPNWMHSQFE
GLDNDQATRNLVGASIAIDQVKVLSREGVKDFHFYTLNRADLTYAICHTLGVRPR
>A0A2U8DHK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MNFLNKHYQETIHNRLESLKNTLQFSFEFFPPKNIDLENKLYLSILKLIKLNPSFFSVTH
GANNGEEKKTYEIVQKIYKKTGVITAPHLTCVNNTPIELEKIARLYWKSGIRNIVALRGD
AKNKMHKHIMYAADLVTFLKKIADFDISVAAYPERHPESDNMKDDILNLKKKIDAGANRA
ITQFFFNIDSYLNFRDQCIKNGINVEIIPGILPIYNFQQLKKFSTMTNVTIPKWIFKMFN
KLEDDLTTQRLIGVNILIDIVKKLFTEGVKNFHFYSLNKSDVVYSTCYFLKSLSL
>A0A395IBF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus homomorphus (strain CBS 101889)|TrEMBL
MHIKEKLSQNEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPVEKVDAALQAAYKAGCTNILALRGDPPREKEN
WEATDGGFRYAKDLVKHIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDNFISWVKNCRDRGISVPIIPGIMPIQTYAAFIRRSEWTKIRIPPDWLEAL
EPVKNDDSAVRNIGKRLVADMCRKLLASGLNHLHFYTMNLAQSTQAVLEDLKLLPSEETP
LQRALPWRPSLGLNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDVTHIFLDFLEGKLARLPWSDSPITAEANAIKDDLIA
LNKKGIFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLIPSYLLDDLIARIEKNG
YLTYHAVSKNGDLRTNTNDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQSVVDDWCLVNIVNNDFHNTSSLFDLFKDLTVKDLDTEVTVEDGQVK
GHQNGAANGAINGTVPNGTSTELPLRN
>A0A6G2M645|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4923|TrEMBL
MGPGTDRPTYSFEFFPPRTAQGERTLWQAIRRLEPLGPDFVSVTYGAGGSSRDRTIEVTK
RLVTETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPKGEWTAHPDG
FHHAYQLVELVRSLGDFTIGVAAFPERHPRSADWDSDIRHFVAKCRAGADYAITQMFFDV
EDYLRLRDRVAAAGCTTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAQHRPDI
AYEIGVAHATLMADRLLAEGAPGLHYITLNKSTATLDIHRNVMSTRSLHAS
>A0A8I1GJX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus group sp. N18|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTNRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQVALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAKVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKKAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>N8Y7B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter gerneri DSM 14967 = CIP 107464 = MTCC 9824|TrEMBL
MSQLSQYLAQNQFCVLVEYLSSSKKIFTVPEQFAGFPVCMTLADRVHSDTDLPPLDVAKL
YPKEVEKLLHFAGKGRDIADFENFLIQAKNNGQHNLLLLTGDKLKQHQFGDAQHPRTRYL
ESVNAVMAAKKVGGFHVGVAFNPFKYAEAEQDAQYYKLRKKIKAGADFIITQLGYDISAL
KQAKDFLNQQAYSPKILACVMPLTLARAKFMLKHQVAGIVITPHMLQVLQQENDAGLTDR
VYLRCALQILLCKHLGYAGIHLSACHQPEEQIRLQSYIEEYRDLDFDACLLLWNSLWNVT
TGHEFFPELIHYSRPVSSGQILKYQHLSFMHDAFFDSKMAKGIGRFIFQSKVWNKSVAAH
ALLKSEFLSKHSVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTHLDRCEFGDRECI
HSVKARLAKAVKQTEILKTKLIPAVSIETRGTSSWKNWFIDATEEV
>A0A6N6PQF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MSFDTPISTLFTRGTPLRSLEFFPPKDDAGVETLKHTAQALVSLKPDFVSVTYGAGGSTR
ERTAQVSALLRKEFLFTVMPHLTCVGHSKEELTSIADKIYSGGFRNIMALRGDPPKGSTE
FVQSTYGLRYGSELVSLLKSRHPEFCLGVGGYPEKHPEAASSELDIINLKKKVDAGADFI
TTQLFYDNNVYFSFVERCRKAGITIPIVPGILPVLSLKQVTRFTALCGASLPAKLVDDLT
HAGDDMEAQEKIGTAWALYQIKDLLKQGAPGYHLYIMNRAKTALALTAGLAS
>A0A846QRM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobaculum xiamenense|TrEMBL
MRIRDLMAKNGQFISLEFFPPKEREAWPKFFETVEQLKGVDPLFASVTYGAGGGTQANTL
EIVRRLKLDQGLEPMAHLTCVGADAERISAFLDELRGMGVDNVLALRGDPPKGAEQFSPD
NEAFAHASDLVRFIRSAHPDMGIAVAGYPEGHPECATFREDYGYLKGKLDAGGDFVMTQL
FFDNRLYWNFVDLMRAMGVTKPIIPGVLPIMSLQSVKRILGFCGASIPGKFLLELEAADA
AGGEKAAYEVGMNWAKRQVRELLDGGAPGVHLYTLNRAQAVLEIVDSLGRLH
>A0A2V5Y0U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIIRGNSPTFSFEFFPPKTPEAAETLYQTIRDLELYTPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEQEIEEILLRYAKSSIGNILALGGDRPVGIAYDKSR
DSFQHAIDLVKFIRRLNESGGHPDRRGFGIGVAGFPEGHPATPNRLVEMDYFKAKVDAGA
DYIVTQLFFDNRDFLDFRERCVLNEI
>A0A538NYM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRGDSPTFSFEFFPPKTPATAEILYQTIRDLESYMPNFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCICHNEDEIEAILLRYARSAIGNILALGGDRPRDIPYDKSR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALADIHIPIIAGIMPVTSMSGFKRIAELAGGARFPAKLL
RALQRCENDPEMVRRVGVHFALEQCHDLLDNKVAGIHFYTLNRSDATRVIFDSLGIPRRR
SAQAPPVQSSD
>A0A3N2MNJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Isolate-104|TrEMBL
MTIPEIIKAKGDRCFSIEVLPPLRGKGIGQLFGNIDSLREFNPAYINITTHRSEMVYKST
PDGLYQRVSERARPGTVAVAAAIQQRYGITAVPHIICSGFSKVETEYALIDLNFLGITNL
LVLRGDKAKHEPSFKPNDNGHAHASDLALQVNSFNRGLFLDGTEMEIVAETPFSYGVAGY
PEKHDEAPNSELDMLWLKHKVDSGADYIVTQMFFDNSKFFDFVDKCRAAGINVPIIPGIK
PIVSRKQLTVLPKIFHVDIPSELASALIDCKNDDDAKAVGVEWCTGQIRELYSRGVPSVH
IYSLNATKSVRSILENIM
>A0A1X1H3C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3A4F2D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nesterenkonia natronophila|TrEMBL
MSSPVARSDDEKRVLASLVANISYEVMPFKSVRAKVLAAVPHEVPLTVTATGKQGLEPTI
ETSIFLREKGYTVAPHVPARMVSGPDELDAVVSRLEAAQVDRIFIVGGDVEEPAGTFTDA
LSLLRSLRERGHHFKDVGVGGYPEGHAKFSQSDIERVLDDKAEYADRILTQICFDPDTIT
AWASGLRDRGVDLPVYVGMPGAVSRQKLMRISAGLGLGQSASFLKKQQNMFWKMFSPSGY
NPSKLVRGLVRNLAQSESTVTGFHIFTFNDLANTEAWRRDLISQSK
>A0A2V6JGH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIADIMREDSPTFSFEFFPPKTPVAVEALYQTIRDLELYMPHFVSVTYGAGGSTRDLTH
NLVERIQHTTKLDPIPHLTCVCHNEKEIEDILLRYAKSAIGNVLALGGDRPHDLPYDKSR
DSFQHAIDLVKFIRRFNESGAHPDPRGFGIGVAGFPEGHPATPNRLVEMDHFKAKVDAGA
DYIVTQLFFDNRDFFDFRERCALADIHVPIIAGIMPVTSMSGFRRIAELAGGARFPAKLL
RALRRCENDPESVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRVIFDSLGIPRRR
NAQAPSV
>A0A1Y4HSB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. An2|TrEMBL
MRVDDIFRNARQANEQPVSFEMFPPKGELTLEQARDIAGELAQLGPDFISVTYSAGGSGN
SGATASIASMISHELGVASVAHLTCISLTRDGLREKIDEFRAAGIENVLALRGDLPAGMS
EAEAGDIAFPYAKDLVPELVDAGFCVGGAAYPEGHLTCEDLNLSVEHLKQKQDAGASFLV
TQLCFDNEYIYRFLDMARVAGITVPITVGIMPFMSKQQITRMVFTCGASLPSPVIKLLAK
YEDDPESLRAAGIDYACRQLEDLAAHGVDGLHVYAMNRPSVARAAMSALRSA
>A0A149PXD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia monticola|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLVPLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHLSCVGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQARSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARQLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIREFGLDV
VTDLCQRLVDAKVPGLHFYTLNAAASTKAICERLGA
>A0A561TLT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces capillispiralis|TrEMBL
MLAAGKTTYSFEFWAPKTEKGERNLWDALRRVEAVAPSFVSVTYGAGGSTRAGTVKATEQ
IAADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWIPHPQGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSAGWDADVAHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNASFPDTLKERILTAKDDPAAV
RSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>A0A6V6Y0C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptoniphilus nemausensis|TrEMBL
MHIRNYFDDSTTKLSFEIFPPNERMTLKSVMAAASRMVGYEPDFMSVTFKADGSGGDQTV
EIAKAVSDIMGVPSIAHLTCSGIPKTELEDRLKELREANIHNLLVLGGDSKRELGEDAYF
PYAKDMVRYFKERGDFTIGCACFPEGNNPALTMEEEIEYLKEKVDAGADFLTTQMFFDNE
VFYRFLDAVRAKGIDIPVIAGIMPITAAGQIRRIADLSGAKLPRTLTDMVARFGDNKEAM
FDAGLTFAEHQMADLAARGIDGVHVYTMNKPAIAERIVNDIGSLFR
>A0A845YG69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symploca sp. SIO2G7|TrEMBL
MTILNGSPATPSPLQSAIANNDFLVTAEVMPPKGGDPSHMITMAQLLEGRVHSVNITDSS
RAVMRMSSLASAFMLKQVGIDPICQMACRDRNRIALQSDLI
>A0A6N3DY74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraprevotella clara|TrEMBL
MNVIDLIQNHKGTAFSFEVLPPLKGAGIDRLFHTIDTLREFNPAYINITNHRSEYVYKDL
GGGIMQRLRIRRRPGTIAVAAAIQRHYDIHVVPHILCSGYTREDTEYMLLDLQFLGISDL
LVLRGDKAKEDAAFRPTGDGYSHATELIGHINRFNEGFFVDGSPIKSPGTSFSYGVACYP
EKHEEAPNPEADLAVLKQKADMGAAYAVTQLFYDNAKYFDFVDRARRAGITIPIIPGIKP
FAKLSQLNVVPKTFHCDLPQALALEIGKCKTDEEAKQVGIEWTVEQCRELIGHGVPSIHF
YTVSAVDSIREIARQIY
>A0A7W5GA06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus endophyticus|TrEMBL
MKPDLREALQQRILTGDGAMGTYLYQMGFPVGVSYEEFNTIRPDVIENIHRRYYEAGARV
IETNTFSANNEKLSKYGLEHEMDAINRAGVRVARAAIGEDAYVVGAVGSIRDGKLKNLRT
AKVIEAYQRQMHALLEEGVDGLLLETFYDLDEMLLALRIARAASNVPVICQFAVEDVGRT
QEGNGMKSAFDQLQEEGADVVGFNCRSGPNGIMRAIDSITGPIGLPLSVYPNAGIPDYID
GKYTYSAGPEYFAESALRFADRGARLIGGCCGTTPEHIQAIAAALDNYVPQIGQPPAPLP
VFEKIIVKPAEKLAELDVIPSKQAIQEPSIVDLVNKRHTVIVELDPPRDLDIRKFMDGAA
ALKEAKADAVTMADNSLAVTRMSNIALAALLQEKVGIRPLVHIACRDRNLIGTQSHMMGL
DALDIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNDGTAFSGKPLKQKAKFV
VGAAFNPNVKHLDKAVQRLERKIKSGADYIMTQPVYDPALIERIAESTKHLSVPVFIGIM
PLASGRNAEYLHNEVPGIQLSDEVRARMAGLEGEAGRAEGVQIAKELLDAALPHFKGIYL
ITPFMFYDMGVQLTQYVWQKTERM
>A0A2S8EY38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium WD3A24|TrEMBL
MPRPRVSFEFFPPKSLEASFRLWDTVQLLAPLKPQFVSVTYGAGGTTRQLTHEAVKTIND
NYGVDVAAHLTCVDATRDETLNIAHGYADAGVNQIVALRGDPPKDAGGFTPHPDGFANSV
ELVEALAETGGFTLRVGAYPEPHPEAADEMADVRYLKRKFEAGADAAITQFFFETDTFLR
FRDACAREGIDKPIIPGVVPIENWKGIRKFAKGCGATIPAWLDDAFEKAERDGREDLLAT
ALCTEMCDKLIAEGVEDIHFYTLNKAHLTRDVCHALGVVPDVSLEKVA
>A0A5F2EGC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira mayottensis|TrEMBL
MKKVSEIYSSAKGPVYSFEFFPPKTLDGDLKLMETVKELAHLDPDFVTVTYGAGGSTRDK
TAQILSEISKNYSFPTVSHFTCVGANQEQIFKALKEIRSSGIVNLMALRGDPPKGEGKFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPNAKSLEEDVENLKRKVDAGTDFLVS
QLFFMNSIFENFLNLVRKAGIHVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A0A3W5N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. HR7|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLYTIEEFN
GKGTPVTPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDKDIQHFVEKVKAGANAALTQFFFNPDAYFYFV
ERIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTESIKKFGHE
VVVKFCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGL
>A0A654BH64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. AX6|TrEMBL
MSVSMGQLEEARRALDAPLFADVAGDLNVSFEFFPPKTAKMEESLWDAVKTLEPLGPKFV
SVTYGAGGSTRERTHATVARIARETSLAAAAHLTCVEASREEIDAVAEEYWAAGVRHIVA
LRGDPPTMGDKFVPHPQGYANAAELTAGLKKLHPFEISVAAYPECHPDSVDQASDIDNLK
RKIDAGATRAITQFFFTPEAFFRFRDAAAAAGITADIVPGILPVSNVAQTRKFAGMCGAE
IPAWMDRLFEGLDDHPGARSLVAATIAAEMCRKLYAGGVRDLHFYTLNRAELSFAICHLL
GLRVKRLAGVVAA
>A0A1H7TVC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas daqiaonensis|TrEMBL
MRFDDEPVPGYSLPILPGHVSPGRLERVLRAGKFAITSEIDPPDSADPAEVLKRAAIFDG
VVDAINATDGSGAHCHMSSVGVCSLLTRVGYATILQISCRDRNRIAIQGEILGAAAMGAC
NLLCLTGDGVQAGDHPQAKPVFDLDSMSLLQIARGMRDDSRFESGRRLETPPRIFLGAAE
NPFVPPLAWRPHRLAKKVAAGAQFFQTQYCFDIEQLRDFMLKVNDLGLLEGPDRVFILPG
IGPLASARSARWIRDNVPGVHIPDAVVRRLEGAVDQKEEGKRLCMDLLHSIREIPGVSGA
HIMAYRQERSVAEIIETTGVLDGRTPWYPGRDDPQKLNPESPDAL
>A0A2G3CF13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum chinense|TrEMBL
MMTNEVLELIGTQGIGASRILAGKPGKASHFANMVDARADLIITQLFYDIDIFLKFVNDC
RQIETNCPIVPETMVIAAPVDMKAPTKLTGKGYVVLTSQRKFKVEINFSAKIPMQAIANA
LHGQESGNSQVALRVLDIILRLYAAKQVKKSIKLLSVYAAIQVCRGSYLNLTGEGAILKR
LHLWQFSDNVTSKDVTDLGTWRLPPVSHAQLSIVVDTLQHASGSTPGPQCPNTFNIHFLT
PQQRTTTCLVSPTVHAFAVPPPPKALA
>A0A3D5RSC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MVDSLNPGLNSPLGSIPKGLKVSFEFFPPKTEKMHENLWLAVERLAPLKPQFMSVTYGAG
GTTRERTHEVVARIQQETGLQAAAHLTCVGATRAEVDDVANHYWESGIRHIVALRGDPPE
GETQYFPHPDGYDYAVDLVAGLKRVADFEITVAAYPEVHPQAESAQADLDNLKRKLDAGA
TRAISTFFFDNDVFTRFRDRASAAGINAPILPGILPLAHFKQACKFAAINGTSIPSWLHE
LFAGLDDDPETRKLVAATFAAEQVRRLIKEGVSEFHFYTLNRADLAYAICHILGIRPKTV
K
>A0A1H6YDQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. OV641|TrEMBL
MTLSINQLEEARHALEAPLFADVAGDIDVSFEFFPPKSAAMEATLWDSIATLSPLGPRFV
SVTYGAGGSTRERTHATVARIARETAVPAAAHLTCVEATRDEIDAVADEYWSAGVRHIVA
LRGDPPRAGERYAAHPGGYENAAALVEGLRRLHPFEISVACYPECHPDSSDAAADLDNLK
RKIDAGATRAISQFFFSPDVFFRYRDAVAAAGMDVEIVPGIMPVSNFAAVQRMSAMCGTE
VPAWMGRLFAGLDDLPAARQLVSATLAAELCRKLYAGGAKQFHFYTLNRAELSFAICHLL
GLRAKPDAVRAAA
>A0A1Q7CQU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriales bacterium 13_2_20CM_2_55_5|TrEMBL
MAGDLLARLKKSPVLCDGATGTLLYAKGIFINRCYDELNVSQPDLIRGLHHEYLQAGAEI
IETNTFGGNSFRLARHSMENRVREINLAGARLGREAAKSFDVWVAGSVGPLGIRIEPLGK
TSYEEARAAFREQIAALVEGGVDLLILETFGYLEELHQAILAAREVNPKIPLVAQVTIDE
DGNCLDGSTPETFTPRLEEWGVDVIGCNCSVGPVAMLEAIERVRAVTSLPLAAQPNAGIP
RSVEGRNIYLCSPEYMASYARKFVAAGVRMVGGCCGSTPEHIRVMKSALRASEARSKVVA
PSASGGVATPLPSPALPVEKRSQLGAKLAAGEFLTMVEIVPPKGTDIRKELEGARFLKSV
GVDGINIPDSPRASARMSNQALSLLVQQQIGIEAVLHYTCRDRNVLCIQSDLLGAAATGI
RNLVCITGDPPKMGNYPDATAVFDVDAIGLVNIVQNLNRGLDIGGNPIGVGTSFVIGVGA
NPGVPNLDEEIRRFEYKVEAGAEYAVTQPVFDLSLLETFLRQIEHCRIPVVAGIWPLVSV
RNAEFMKNELRVSVPNSILDRMAQAKTPEAAREEGIAIAREMLVAVHHMVQGAQISAPMG
RYASAVDVLEALGSSRPATA
>A0A6N7AKF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MRAYDHDGTGNIQADAPRLVLPVATVLPGPVSVSFEFFPPKTEQMGETLWACIRRLEPLA
PRFVSVTYGAGGGTRERTHDTVVRIARETSLRPAAHLTCIGATRAEVDTIARRYWDAGIH
HIVALRGDPPDGQSRHVPHADGYAYAVDLVRGLKTIADFEITVAAYPESHPEAPSAAFDL
NNLKRKIDAGATRAITQYFFDVNIYRRFMDKVRAAGISIPVVPGILPVTNVATVLKFSRT
CGASVPAWMHTLFDGLDADPETRRLVAAVLAAEQCRALAAEGVEHFHFYTLNRADLVFAI
CHILGVRKQ
>A0A8E0BGD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus M809|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A5I0EWK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Kenya|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A432LZN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella choica|TrEMBL
MPAISFEFFPPKTDEQRAQLDKAAKELKGLKPEYVSVTFGAGGSTLSYTSETVARLHRQH
GLEVAPHLSCMGGTRKEIADLLDIYRAAGYRRIVALRGDLPSGMASPGDFRYAAELVRFI
REHCGEHFHIEVAAYPEMHPQAEDVHADLKHFKAKIDAGANGAITQYFFNADAYFRFVDD
VRRLGVSVPIVPGIMPISNYAQLKRFSDACGAEIPRWIAKRMQAYYDDVESIRAMGAEVV
AQLCRRLLEGGAPGLHFYTLNRTKATRAVLDQLH
>A0A2I1MVF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium aurimucosum|TrEMBL
MSPRLSASAPLDQISEDTPKRPQRTALSFEVIPPRHDADAKKIDRLLDTLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTEEELVGWIDTLVDAGVRGLLALR
GDLPEGGMPEGHLPHADSLVRLIRRWESARVARLAAGRLAVGVACYPNGHAESATPDEDI
DVLLSKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPPQVLDQLAAATSPEEEKEIGMQLTASLAKSVMNAGADGLHIYTHNNPDITTDLL
HRIGVTP
>A0A2D4SJ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MTSISLEFFPPKSAETEAKLWDVINELAVIRPDFVSITYGAGGSTRDRTHKCVKHLVTKT
DLKPAAHLTCVAASKSEVDEVIEDYALAGVKHIVALRGDMPDMEAFSPHPNGYRGSVELV
DALSRRGGFDVTVSAYPEKHPESGDMQTDIDLLKAKIDAGATRAITQFVFDTEHHYRFRD
ALADNQINIPVIPGIMPTTNFKGVLRMSEACGASVPDWMKSKFEGLDDDLESRRALAIEV
ATEQCRDLIKSGFENLHFYTLNQVTVTQAVCNTLGIEKVGVQQ
>A0A2P0A0G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pseudopneumoniae|TrEMBL
MSRQTLSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLETCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A1V3QSM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. A49|TrEMBL
MSPDYNPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPHDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNVMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLNEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRQPWKRETLPTDALVASRMEHIREGKEENQQEMAEAAAH
HPH
>A0A4S3Q434|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria rosea|TrEMBL
MPIDPPHAGPAAALLRDFSLEMTGKDVPALEEAAAVVPAGTRINVTFLGNEDLGMRVDAA
RAVREHGFVPVPHLSARRLRSQGELEEFLAALAEVGAAEHVFVVGGDPETPEGPYPDSLS
VIRTGVLPRHGVRGVGVSGYPEGHPGIDDAALWSALTDKTAAIREQGLEPEIITQFGFDK
DPVLEWLAEVRRRGVDTPVRIGVPGPAGVRRLLGYARRFGVGTSAGIVQKYGFSLTNLLG
TAGPDRFLRDLAAGLDPAVHGQVLLHFYTFGGLRATAEWVREFGTDGRTP
>A0A1V2T923|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia donostiensis|TrEMBL
MTFDNARGRSTPYRPSPTSPNVSATPSVVQSLQLHSGSAVPFSVEFSPPRDAAGEERLWR
AVRTFERMHPAFISMTYGAGGTTRDHTVRITGELAEETTLLPVAHLTAVEHSVAELRSIV
GAYADSGIRNILVLRGDPPGDPLGEWHKHPDGVEYAEELVRIVRDLGDFHVGVASFPQGH
HRSPDLDHDTAHLAAKLRAGAEYSITQMFFDVEHYLRLRDRLVAFDSVEGAKPIIPELMP
ITSLRTVKRAEELCGRPLPQAVLDRLHRAAGNGAEEDRAAVREVGIQIATEMGQRLIDEG
APCLHFITLNFAKATSEVLTNLGYGVTAAPVSA
>A0A285PPD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum hallii|TrEMBL
MNTMQTNPQDILKTLSLSFEVFPPKKWEDFPGLYETLDELKGLHPEFISCTYGAGGSNSK
KTAEIASHIENELGIRSIAHLTCAALTEDKLLSTIENFKNAGIHSVLALRGDKPFDMSEE
DFANRQYKHPSEIIPILKKAGFRVAAACYPEKHYEAPSMEEDLHWLKHKVEQGTDALISQ
LFFDNNAFYRFMDVADQKGITVPVHAGIMPITSAKMINTTINLSGASIPKALSDLIATYG
ENPSDMRKAGIEYAARQINDLAEQGMHYVHIYTMNHSETAKEICDLIR
>A0A2E6NZT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MVNLSFEFFPPKTEESEKKLWSSIKXLAPLNPKFVSVTXGSGGSTRNRTHKXVEKIINET
NLKPAAHLTCVSSSXMEVDQVIXNYHEIGVXHXVALRGDMPXMGTFXPHPEGYSXSVELV
KTLHNFGXXEITVXTYPEKHPESKSIXDDIXFLKXKIXAGANRAITQFVFDXEILFXFRD
KXEAAGINIPIIPGIMPTTXFKNVXNMAQKCGATIPNWLEKKYEGLDDDLKARRXXAKEV
GLDFCKKLISNDYINLHFYTLNQADLTYDICSSLY
>A0A2A4RPC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichales bacterium|TrEMBL
MTYENSYSCEFFPPKTEKGTENLRKTLSELATLNPAYFSVTFGAGGSTQEGTFDTVKAIQ
EKGYAAAPHLSCIGSSQESIRELLNGYVELGVERIVALRGDMPSGMRETGAFRYANELVE
FIRSETGDHFHIEVAAYPEFHPQAPNAQVDMENFARKVKAGANAAITQYFYNANAYFRFV
DDCEKLGVDIPIIPGIMPITNYSNLKRFSDMCGTEIPRWIAKRLDGYGGDKASLVAFGEE
VVTDMCQKLLDNGAPGFHFYTMNQTGPTQKLWHNLGISNKP
>A0A2N0TM37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salegentibacter salinarum|TrEMBL
MKVTEHINRAKGETLFSFEIVPPQKGRNIQDLYNNIDPLMEFNPPFIDVTTSREEHVYIK
KEDGLLERKITRMRPGTVGICAAIKQKYNVDTIPHVLCGGFTREETEYLLVDCHYLGIEN
VMALRGDAMKHQRYFEPTNGGNCFASELVTQIKDLGAGKYLNEVIESDNNADFCIGVAGY
PEKHLESPSLQTDLKRLKEKIDAGADYVVTQMFFNNQAYFDFVEQAREAGITVPIIPGIK
PIAVKRHLQLLPQVFSIDMPEELIKDVEACKSNVEVRKVGIEWAIAQSKELKAAGVPVLH
YYSMGKSTNIQKIAEAVF
>F3IG09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. lachrymans str. M302278|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1I3VN00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter persicus|TrEMBL
MESQKQFKRRFSFEFFPPKTDKGREKLQNVRNELAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRQEIGELLDLYKENGINRIVALRGDMPSGMGASGELRYAN
ELVAFIREHSGDHFNLEVAAYPEFHPQARSAEDDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSESIRQ
FGEEVVTRMCEKLLAAGAPGLHFYTLNQAQPSLSIWENLGISEREKISF
>A0A3E0H988|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraperlucidibaca baekdonensis|TrEMBL
MSHFSIEFFPAKTEVGAEKLRDVARRLGAISPEYFSVTYGAGGTTRDRTLGAVRDVQALG
YAVAPHLSCVGDSKAEIAELLTTYREMGIKHLVALRGDLPLDVVARSKELPYAADLVRFI
REHSGEHFHIEVAAYPECHPQAACLADDVRHFVAKANAGANSAITQYFFNADCYFHFVDR
VRAAGSDIAIIPGIMPITNFKNLVRFSDACGAEVPRWIRQQIASYGDDSASIIAFGEEVI
TRLSQQLLDGGAPGLHFYSMNQAEPTLALWRNLGLPT
>A0A1Q3PAT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter sp. 50-39|TrEMBL
MFLNKIKSHESGVVLYGITPPKADTTIERVAEIAQKTMERLAALDIDALVVYDVQDESAR
TKEERPFPFQNSLDPLLFASEHLGTLDVPKIIYRPAGKFSGEELSEWLDVLHKQRFYPVF
VGVPAPDFPVRTSLPEAYRIWRKHEETSVIGAVTIPERHKLLQDEDVRILDKMECGVSYF
ISQCVFNIEYAKQVIEDLAQRCDSRKVVPPTIIFTITACGSEKTLQFMDWLGINVPEDVK
EDLRQSGDMLERSVNICLDIASELTAFCMQRSIPFGFNIESVAIRKAEIEASVFMAKQIS
QMLRDKGVRKSVRPESVGTTTSS
>A0A511ETW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum extorquens|TrEMBL
MPNASQHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVDATKEEIDGVVQSYWDAGVRHIVALRGDPAEGVG
HSYRPHPGGYAQTCDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIEALKAKVDAGADQ
AITQFFFDNEIYLRYRDKVRAAGIEIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLENDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
PAVKPEAKAA
>A0A8C2L1B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGKDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIITQLFFRAETFLKF
VKDCRAIGISCPIVPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNCRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQVNTILRARLCHVISCFYIDIMK
>A0A163LG80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rossellomorea marisflavi|TrEMBL
MNTLLDALSENILIADGAVGTLLYSYGVDRCFEELNLSHPEEIINVHKQYIEAGADIIQT
NTYGANYAKLSRYGLQDQVKEINEAAVKLAKKAAKEGTYILGTIGGIRAINQHISLEEVK
RGFREQLYCLLLEGVDGILLETYYDFEELRTVLQIVKKETDLPVIAQVSMHETGVLQNGM
DIKDALGELELLGADIVGINCRMGPFHMVKSLEGVPLPKSSFLSVYPNASLPNYEEGRFY
YAAEPDYFGDISNELRLQGARIIGGCCGTTPAHIKAVKERMISRVPVKEKKVKRQELIKL
KDPLLQKSLLHHKVKEKKTLIVELDPPKHLDTGLFFQGAKALKEEGIDAITLADNPLASP
RVSNDAMGTLVQQKYDLDPLVHITCRDRNLIGLQSHLMGLHTLGIHNILAITGDPAKIGD
FPGAASVYDLSSIELIELIKQNNEGLSFSGKSLRQRTNFSVGAAFNPNFRHLDASVKRLE
KKQSAGADYFISQPVFSCEHLVQIAEATRHLQSPLFIGIMPLISSRNAEFLHHEVPGIKV
PDQARRLMKEAEGDPLQSRAVGMGIAKELVETAMELFNGLYIITPFMRYDMSVELIRHAN
VIEKEKREVPYDHNIV
>A0A8C2CCH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCECDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGAHFIVTQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNCRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQEEGTF
>A0A7X8VNZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MKKKNILEAIREQLLIFDGAMGTELYQRHVFTNRSYDELCLSDPELVIEVHQDYLRAGAD
VLTSNSYGANRSVLQKFGLADQVAAINHKAVELMRLSLERLAPQRQVYLAGSIGPLEPGL
RQKMPRQEAVQAFVEQAEALSEAGVDFIIFETMPDREAALQASLAMSSLENPPPFVLSHA
IPDGEDLAEILAHRLQPLQAGLPAPFALGLNCGLGPARMLEALTAARTLTELPIIVQPNA
GTPHKVENRQLYLCSPEYLSTYAQRYVNLGARGVGGCCGTNPEHIAELARSLKRLSQSYS
SISVSEAQKPKAAAAQETALAEKSRLGQKLARGEWIKSVEITPPRGWDTAQIISKARLCQ
QQGVDAINVPDGPRAAPRLSALITALKIEQEAGIEAVLHVCSRDRNYLALQADLLGSAAV
GLRNFLFITGDPPKLGGYGYASGVFDTDSIGLVSLQKHLNQGIDLGGQQIQPPSAAVIGV
GADPNAIDFNREITRLQAKIEAGAEFIITQPVFDVEALHKFMRVIAEWKIPVIAGIWPLA
SLRNALFMKNEVPGVLVPDSIVRRIEKAQTREEQLACGIQIAREALAELRGMVAGVQVSA
PLGNVNAALEVLA
>M9LZE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus popilliae ATCC 14706|TrEMBL
MLQGEVIVGDGAMGTYLYQLGYPVGISYESLNISAPERIRDIHREYVSAGARLLETNTFT
ANREKLSKHGMEKQVKAINRAAAQLAREAAAGHAYVVGALGSIRAGKRENIATDQVNRDY
TEQLSALLEEGVDGIMFETFYDMEEMKLAVQIVRALDDRIPIICQFAVEKSHRTKDGLRL
LDAFRLLREKGADVVGLNCRMGPNGLMRAMEDLAGRLALPMSAYPNAGLPDYVDGRYNFV
ATANYMAERAVRFADLGARIIGGCCGTTPDHIQAIALALADAKVTVLPTLAKEEARAVRP
LEIGDHGAESVSGQGTTAREPSLIDTVRERHAVIVELDPPRDLDIAKFMLGAQALKDAGA
DALTLADNSLAVTRMSNMALGYLALDKIGIRPLIHIACRDRNLIGTQSHMMGLNALGIDH
VLAVTGDPARFGDLPDSSSVYDLTSFEIIRMIKQLNSGLAFSGKALKQRANFVVGAAFNP
NVKHLSKAIERLQRKIEAGADYIMTQPVYDASLSERIAEGTKHLNVPVFLGIMPLASGRN
AEYLHNEVPGIHLSDEVRERMKGLEGENGRREGVAIAKDLLDVAMKNFNGIYFMTPFMFY
EMTVELTEHVWQKAERPTDPLYRHT
>A0A1R0XYQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus odorifer|TrEMBL
MKPDLRSAWGNKVLVGDGAMGTYLYQKGFPVGISYEELNLTSPGVIEDVHRSYIEAGAVL
LESNTFSANYDRLSKYGLESKVEEINRAGVRIARRAAGDHGYVLGAVGSIRAGKRANLSS
TELKKYFTQQIAALLDEDVDGIMLETFYDVEELHLALRTLRKISSLPVVCQLAVDETART
LDGLTLPEAFRILESDGADVIGFNCNTGPNGMKRALKAVQGSLVLPVSVYPNAGVADYVD
GEYRYGASPEYFGQMAQTFAEMGCRIIGGCCGTTPQHIAEISTALKNYVPQPLPKPLPPT
VERVSLQDNFGDEDREGREPNLVDLVKERHTVIVELDPPRELDIAKFMQGAEALRRAGAD
ALTLADNSLAVTRMSNMALGHLVLAKTGLRPLVHIACRDRNLIGTQSHLMGFDALGIDHV
LAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGISFSGKPLKQKANFVIGAAFNPN
VKHLDKAVQRLEKKIASGADYIMTQPVYDQELIVKIAEATAHLEIPVFIGVMPLASGRNA
EFLHNEVPGIQLTDDVRNRMKGLEGEAGRAEGVAIAKELLDVATAHFNGIYLMTPFMFYD
MSAQLMEYVWEKSGRKLSPLFR
>A0A8C1BMK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
SSILAAHTSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRWFSL
EFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGL
ESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGGMNTLAADRQNLTGLLQLMAKGMS
EPIKDNDAAIRNYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPR
RPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYY
LFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPET
NLLKDELEKVNRRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTA
LLQVLKKYEPRVNYHIVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWK
DEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLD
SPPETQED
>A0A1R0ZNK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus odorifer|TrEMBL
MKPDLRSAWGNKVLVGDGAMGTYLYQKGFPVGISYEELNLTSPGVIEDVHRSYIDAGAVL
LESNTFSANFDRLSKYGLESKVEEINRAGVRIARKAAGDTGYVLGAVGSIRAGKRANLSS
TELKRYFTQQITALLEEEVDGVMLETFYDVEELHLALRTVRKHSTLPVICQFAVDESART
LDGLTLPEAFRILEGDGADIIGFNCNTGPNGIKRALKAVQGNLILPTSVYPNAGVADYVD
GEYRYGASPEYFGQMAVTFAEMGCRIIGGCCGTTPQHIAEISSALKDYVPQPLPEPSPPT
VERVSLQEHFGEDEGRDGREPNLVDLVKERHTVIVELDPPRDLDIAKFMQGAEALRRAGA
DALTLADNSLAVTRMSNMALGHLVHAKTGLRPLVHIACRDRNLIGTQSHLMGFDALGIDH
VLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGISFSGKPLKQKANFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDQQLIVKIAEATAHLDIPVFIGVMPLASGRN
AEFLHNEVPGIQLTDDVRNRMKGLEGEAGRAEGVAIAKELLDVATAHFNGIYLMTPFMFY
DMSTQLIEYVWEKSGRKLSPLFR
>A0A1G7NRH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter delicatus|TrEMBL
MTTPAVSFEVFPPRTVGAAFKLWDAAQALAPLAPRFFSVTYGAGGTTRDLTQDSAHVLHR
TSGLPVAGHLTCVGASRAETLEVAEKFAEAGIKDIVALRGDPQAGTDKFEPHPEGFANSC
ELIEALAKTGKFTIRVGAYPDPHPEAADQQANIDWLKRKFDAGADEALTQFFFEPETFLR
FRDACVKAGIDKPITPGILPVVNWTSARKFATKCGTPIPTWVDQAYEAAIRDDRHDLLAQ
ALCTELCSELIDEGVDALHFYTLNRAELTRDVCRAIGVTPQVGLSDVA
>A0A1G7JYD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporolituus thermophilus DSM 23256|TrEMBL
MLIHQLFAQKRPVVSFETFPPKPASPLESIFQCIEELQALKPDFISVTYGAGGSTRGRTL
EVARHIQHDHGIPALGHLTCVGATAATIQAILHEFAAQGIENILALRGDPPKDAPIPPTP
YRAKDLIRFIRQQRRPCSIAAAAYPEGHLESPSREDDLRFLKEKVDSGVDFLITQIFFDN
AMLYRFLEDARALGIDVPVMAGIMPVFSRPQVERICSLCGATLPPALVKLMDKYGHQKEA
MEQAGLEYASRQIEDLLAHGIDGVHLYTMNRPHLARTLVRNTGLR
>A0A4V5NQ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus sp. IMCC35007|TrEMBL
MHISKIFEQNPIAFSYELFPPKSKESADQLFATISDLSPLELGYVSVTYGAGGSTRDLTH
ELILRIQKETDLTVVSHLTCVGSTRDEIQSILDTYVASGVENILALRGDPPKGQGPFEPV
DGGFKYAFEMVEFIRKHYPQMGIGVAGFPEGHPETPNRLQEIDYLKAKVDAGADYICTQL
FFDNNEFYDFCERCELAGIRVPIVAGIAPITSVKLMQRMAEVSAGTRFPARLIKSMYRAE
NEEYQAKVGTHWATEQVRDLIDHNTRGVHLYTLNRSNATRQIYDSLGVTTTRGLV
>A0A2S5EK81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrotoga halophila DSM 16923|TrEMBL
MKIVDLIKQSNKPVLSFEIIPPNVGESIDSIFNVVDNLIEFSPKYINVTKHANEIDYVEE
NGKIMKIIQKKRPGTVGVSASIKHRYNIEVVPHLICTGFNKYQLEDILIDLNYLRIENIF
VVRGDKKRYTWKETDEYEHASQLVEQIANMNRGIYTFPTKEHNSTNFCVGVAGYPEKHFE
SPNFEKDLDYLKLKVDMGATFIITQMFFDIEYYKNFVNKVRDLGIEVPIIPGIKPLGSKK
TLYNIPKTFHVNIPKSIVEEFENAKSSQDEYIIGVRHAIKLIEQLLELGVPGVHLFTMGK
GKIVKDVLSAFKGIF
>A0A2N2DKF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-14|TrEMBL
MGLKEKLGKQFIITTELGPTDGTDVQTTLEKARSYIKLDGINIHDCPMARLRINSIALAH
IVQSELGIDTIPHFTCRDRSLLGTQADLLGAHALGIRFLLPTTGDPPNHGPFPSSAVYDL
NTLSLISLIKKMNQGQDAANKEFKGPTDFMVSGTTSTSAANMGAVYSRVKRKIDAGVDFF
QTQPCYDAEKALAFAEKMKDFGKPVIMGMMPLKSVKMAEYMNDSVEGIEIPEEVLAKIRE
GVPGARIACEFVDKVYKHIDGIHIMAMGDVKASNEIIEHTLSLIGA
>A0A1M3TYK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus luchuensis (strain CBS 106.47)|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSNWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVDFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A1J3CZC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noccaea caerulescens|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFGCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIADNGLASNEAYQSDLEYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTK
IPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANIFRTKEDVRPIFWANRPKSYISRTKAWEDFPQGRWGDSRSA
SYGALSDHQFSRPKARDKKLQQEWVVPLKRVEDIQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLVKINSKGFLTINSQPSVNAEKSDSSTVGWGGPGGYVYQKAYLEFFCSKEKLD
AVVGKCKSLPSITYIAVNKGDNWVSNTAQSDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIFGVFADL
>A0A1N6R8Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbispora rosea|TrEMBL
MALGLPSRLPDRVPTVRELLAAGERSFSFEFLPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPRGGNPLDEWVKHPEGVLYAEDLVRLIRQAGDFCVGVAAFPYKHPRSATIESDTKYFV
QKCRAGADYAITQMFFRAEDYLRLRDRVAAHGCDTPIIPGIMPVTQMSTIARSEQLSGAP
FPPEVAERFAAVADDPAAVRRLGIEHAIEMCQKLLDEGAPGIHFVTFNRSSATREVFQAL
HSVPAAVTG
>A0A660UIS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSHRLKDCLNSGEFAVTAELTGSPGYNFSPIEKFLSAHQEKKAAIPGGFSFVGITVPQNP
GGVANIDPSDVLAVIEKKNLLDDLDYIPHLSCKDNNVDSLTSTLVGYRQRHIESVLALTG
DKPITSQGVFEVESIGLLSLIGKLNHQSITKAKPGQWDQVRQFCAGAAVSPFKYTEASLM
QQYYKMEKKVAEGARFLVTQVGWDWKKSLELAQYCKDNSISTPLVGNVYWLTTKTPAPRL
MHDIKLPGCFVSDDLLAKLQSESIDEHIERAAQQVAMYKSMGYAGVDVGGVHDYDIFLKI
LNRADEIGDGWQQYKDNLYWPAEKPFYLYDEAGKQVSLSKPKRKCNERFFDFMHRAILDS
DYKGFHCLKWVLKLFRVNKESGFTYKAFNAIEKSFKYCAFDCAECGDCYLPENFGYCTIG
GCEKGMDNAPCGDSTVDGYCGNNLERLCIGERIYDSAAAKTDGREKLRTMLNKPRIAALE
HTSSIVNYLFGKDHTMTTPLIGIGESIHASIPKTGKIMKELHDLGADAYTKESGPLNYIR
ALVEEQADDDAAYIAVNLDAFGESDPQQAVGMMVDYTKLVRQWSKGVPICIDSSNDDVLI
AGLKEWYNTDEVVKPPLLNSIKTHTTDKMMALKKTYDFSFIGLLVSEDKATGPGGSHSVE
ELFGLAKEIFDKAMQYGFKPEEIYFDSTVFPIAIDMPMEPGVPGYTYRAFETIKKIKTDP
QMKNCHCSLGLSNSCRDLPGRRIGIARAYT
>A0A7C3FDV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTEKNTNGLKSGSNLERILREGHFAVTGELGPPQSADGAVIREKAELLKGYCDAANITDN
QTAIVRMSSIGAGAIVQQEGLEPIIQMTCRDRNRLAIQSDILGAYALGTRNVLCLTGDHQ
SFGNHPTAKNVHDLDSVHLIQMVVKMRDEACFDCGDEMKGVEPRFFVGAAANPFGDPFEW
RPYRLAKKVKAGADFIQTQLIYNTERFAEYMQKVRELGLHEQVYILAGIGPLKSPGMARY
MRDQVPGLDVPNKWVDRMTEATKGIDKDDKKARRDAWRQEGISIAVDLIKELRQVEGVAG
VHVMAIEWEEAVKPIVDGAGLLPRPELSPLPPSDPKKKAS
>A0A7V8TUH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodospiraceae bacterium WFHF3C12|TrEMBL
MTPSYKNSIRESIESGAFLYTLEHVPELLTRKEQGLQELAREAKGVARDDRVRGVNIGDR
VKSMDSCSTVMCGRVAAEASGKMPLLHLAGKDRTPEEAAKVFTQAHSYGLNTFLIVSGDR
ILEKTRPGRPRYNDSIIGIKQARELVRDAFIAAAVSPFKYREEELLNQYLKFVKKINAGA
DYVITNVGWDMRKFQELIWYRNARNLDTPIVANLLLPRPGWAKAINAGRLPGVHMSDDLY
KKMSEELQQGVWEEASFNRLALSILRVKRMGYAGVQLSGVDTYEQLTSVIDRVDYLETKL
ISNDDLIAAWDEAHRLGDGRMVDFAPSDPIYLFGEDEAPQPGSLNGPPVLDGANASSPER
RKYHAMHFIHEHAFKKKSIGAKVLAPLMRAIDSTTLGRRWLFKLEHAVKKSTLGCDACGF
CRIQYLAYTCPETCPKGLANGPCAGTDENVCEFKDRECIHNRKYRIAKSVGRLKDLETVY
VPPVPTATRGTSSWVNEYTDRVPRVETFGDQTIVTGNGRDRQPQQSREKEAQSNSYSAAR
>A0A6L3A730|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRIREQIDEHGPTVSFEFFPPRDEVGFWDLYRTVEALRPLTPDFVSVTYGAGGGTRRKTL
DLVARIKSDIGLEPMAHMTCVGASRNEIAGILDELVIKGVENVLALRGDPPEGTSAFTPV
PGGFRYANELVTFIRERYRFCVGAACYPEGHTEAPTLDIDLENLKRKVDAGVHFLISQLF
FDNDAFYRFRDRAERAGIHVPILAGIMPILSVKQVKRFTQMCGAAIPRDLLHRIESVEDD
NEAVRHVGMFHATQQCLGLLACGVAGIHFYTLNRSTATRAIYQYVRGELPKRRASRSDSG
PH
>A0A8G0UKQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diaphorobacter sp. MNS-0|TrEMBL
MSLSTAFPVSFEFFPPKTPEGADKLRAVRQQLYARRPEFCSVTYGAGGSTQAGTFGTVRE
ILAEGVSAASHFSCIGATKDSVRAQLAELKAMGVKRLVALRGDLPSGYGIGGEFHYASDL
VAFIRAETGRDFHIEVAAYPEVHPQARSSDADLQAFATKVRAGADSAITQYFFNADAYLR
FVQDVRRLGLDVPVVPGIMPIMGASQLLRFSDACGAEIPRWIRLRLQGYGDDVASIRAFG
LDVVTHLCEQLRREGVPGLHFYTMNQSAATLEICDRLGL
>A0A7V5YWD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MKSGSNLERILTAGYFAATGELGPPKSADAQVIRRKAQILKGYVDAVNITDNQTAVVRMS
SIASGALLIQEGLEPIIQMTCRDRNRIAIQSDLLGAYALGMRNLLCLSGDHQTFGNHPGA
KNVYDIDSIQLLQIVRGMRDEKKFQCGEAMDVEPRFFLGAAANPFADPFDFRPLRLAKKA
KAGADFVQTQLIYNVDKFREYMKRVRDLGLHEKVYILAGVGPIKSPAMARYMQTKVAGMD
VPDWVVQRMEKAPKEERKKEGIRICAEIIQQVREIPGVAGVHIMSVEWEEAIPEVLELAG
LLPRPNLGN
>A0A7W7P192|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas nitritireducens|TrEMBL
MSQKERRFSFEFFPAKTEAGHEKLLATARQLAAKKPDFFSCTYGAGGSTRDRTLTTVLQL
DGEVQVPTAPHLSCVGDTKAELRALLAHYKDSGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRAETGDHFHIEVAAYPEVHPQARNFEDDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAEKLGVSIPVVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDIASIQAF
GEQVITDMCERLLEGGAPGLHFYTLNQAEPSLALWNNLKLPR
>A0A7C3AZB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTENMTNGYKSGSRLERILRAGHFAVTGELGPPQSADGEVIRKKARLLQGIVDAANITDN
QTAIVRMSSIGAGTIAVQEGLEPVVQMTCRDRNRLAIQSDLMGAYALGMRNVLCLTGDHQ
SFGNHPTAKNVHDLDSLQLTQMVVKMRDEKCFQCGDEMKGAEPRFFVGAAANPFGDPFEW
RPYRLQKKVKAGADFIQTQLIFNIERFAKYMEKIRELGLHEQTYILAGIGPLKSPGMARY
MRDQVPGLDVPDIWVDRMMGATTGIDKEDKKARQDAWRREGIQIAIELIKELKQIEGVAG
VHIMAIEWEEAVKPIVEGAELFPRPEPTSLPTSDTETAA
>A0A0E4CWI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus riograndensis SBR5|TrEMBL
MKPDLRSAWKNNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYIGAGAVL
LESNTYSANYDKLSKFGLEAKVGDINRAGVRIARRAAGESGYVVGAVGSIRAGKRANLSG
TELKRFYTEQFSALLEEQPDGILLETFYDVEELHLALRSVRKLSDLPVICQLAVDETART
LDGLTLPEAFHILEQDGADVIGFNCRTGPNGIKRALKSLQGNLKLPASIYPNAGIADYVD
GQYRYGASPEYFGQMAPVFADMGARIIGGCCGTTPQHIAEISAALRGYTPQPLPEPTGQR
DPERLIVQEHLAEDEERDGREPTLVDLVKERHTVIVELDPPRDLDIAKFMRGAEALRKAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIKQLNDGIAFSGKPLKQNANFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIARIAKATEHLEIPIFIGIMPLASGR
NAEYLHNEVPGIQLSPEVRSRMQGLEGEAGRAEGVRIAKELLDAATAHFNGIYLMTPFMF
YDMSVQLLEYVWAKQGRKLSPLFR
>A0A7V3K2J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTDTNGYKAGSRLEKLLRAGYFVATGELGPPQSADRSVIERKAAHLRGHVDAVNITDNQT
AVVRMSSIAVGKILLELGIAPTIQMTCRDRNRIAMQSDLLGAWALGMRNLLCLTGDHQSF
GNHPMAKNVHDLDSIQLIQMVRRMRDDKVFQCGDPIKGQEPRFFIGAAANPFADPFDFRP
YRLAKKVKAGADFIQTQLIYNVPKFAEFMKRVGDLGILDDFYMLAGVGPIKSLGAARYMA
TKVPGMEVPDELVERMRKTPKEKQAEEGIKICAEIIQQVREIPGVRGVHIMAIEWEEAVP
EIVSQAGLLPRPEI
>A0A660W8P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MIFWAAIKRYRSLTKGKSVMRKKLIEKLEDKSSFVVVAELTGGPGFNFSPIEKFLTAYKT
ASSSAIPKGFDFVGITATQNPGGVANIEPADVLSQIKLNNLLGDLDFVPHISCKDQNTDA
LISSLAGFKKAGVENVLALTGDKPVKAKGVFELDSVGLLDLIKKINHESYIKARPDALEN
VHQFFAGAAVSPFKYTEPSQMQQYYKMEKKITCGARFFITQVGWDWKKSLELFRYLKENE
LDVPIIGNVYLLSTITPAPRLMHDIKLPGCFVSDELLAKVYSENVDDHIERAAQQVAMYK
AIGAAGVDIGGVHDFGMFLKILDRAGEIGSGWEEYKNNLYWPAKEGFYLYDEAGKRATPT
KYHKKFKQRFFNFFHRTVLDSDYRGFHAFKRIMSALGTEKGKGGIYKLFNAFEKAFKYLL
FDCEECGDCYLPENFGLCTMGGCEKGMDNAPCGDSTVDGHCGNNLERVCIGELIYEAAAA
EKNGLERLRTTINKPRNPALEHTSSILNYLFGKDHTMQNALITIGESLHASIPKTGRIMK
ELAELGPDAYSTPSAPLDYIKALIESQVADGADYIAVNLDAFGEQDPQTAIDMMIEYVKM
VRKWSNGVPICIDSSNDDVLIAGLKEWYNTDEKVGQPLVNSIKTHTMDNMFPLKRHYDYA
FVGLLVGEEKNSGLGGSHSVEGLYSMAKQIFDEAVNKYGFKPEEIFFDSTVFPLAIDMPM
EPGVPGYTYLAFETIKKIKSDPKMKAAHCSLGISNCVRDLPGRKIGVCRAYVAKAMEYGL
DAGIVNTAHHYGQVEPDAELVKLVDTYARMDGSAEMLNEAIRLMGKFCQDNRKPD
>A0A2M8FMJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium CG_4_9_14_0_2_um_filter_37_13|TrEMBL
MKSFRERLGNELILFDGGTGTYLYEKGIYINRCFDELNLTNPELVTEVHCDYINAGADII
ETNTFGANSFKLTPHGLGNKVYEINLRGAKLAKTAAKESVLVAGAVGPLGVQIEPLGKLS
FDEAKDVFKEQIKGLLDGGVDLIVLETFALVKELIQAIRAVRELNADIPIVAQVTINESG
TLLSGAPLERFIEKLKDYPVDAVGLNCSVGPKAMLDALENLRSLTDIPISVQPNAGLPQN
ISGRNIYMTSPEYMAEYAKRFIQTGANIVGGCCGTNPTHIKAMRKAVQALQPVKRMDVKI
ADLQVEKPSEIKIYEKNEKSRLSNKLLKKEFVKLVELVSPKGVSPSREVDKARKLYHAGI
DAINIPDGPRASARMSALALAAIIQKEVGIETVLHIACRDRNVIGMQSDLLGAWALGLRN
ILAITGDPPKLGNYPDATAVFDVDAIGLTNIINRLNHGLDIASNPIGDPTGFCVGVGVNP
GAINLDEELKRLEWKIEAGAEFMITQPVFDIKLLEHFMKRIEKIKLPLICGIWPLVSFRN
AEFMNNEVPGASVPQKILQRMKKMTTKEEGFNEGVKIARETFDQVKTFADGVQISAPLGR
IEAIFDMIE
>A0A7Z9ZIK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MAEERTNGYKSGSNLERILRAGHFAVTAELGPPQSADPEVIRYKARLLKGVVDAVNITDN
QTAIVRMSSIASAVLAMQEGIEPIVQMTCRDRNRLAIQADLLGASALGVRNLLCLTGDHQ
SFGNHPTAKNVHDLDSIQLIRMVKEMRDEGRFQCGDEIKGEVPRFLIGAAINPFADPFEF
RPYRLAKKIAAGVDFIQTQIVLDIDRFRAFMKRVVDMGLHEKVYILAGIGPLKSAGAARY
MRDKVPGMRVADEYVERMRAAVKGIPKEEKKARRKAWRQEGIRIAIEQIQEIREIEGVAG
VHIMAIEWEEAVKPIVEGAGLLPRPEV
>A0A2D6HKE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRISEIYDGERPVFSFEFFPPKTAEGAGKLLATVADLKDALAPDFVSVTCGAGGSTRDRT
LECVTGIQGNLGITAMAHLTCAEVSADDIRENMQLLLANGVENLLALRGDPPADGRRMVT
VQDGFAHASDLVEFLEDNYDVDIGGACYPEGHIESSGLDEDLQWTRHKIDRGARFLITQL
FFDNAHYFGFVERARSAGIDVPIVPGIMPITNRVQVERFTAMCGASLPEELAERLARCGD
DAAKCMATGIEHAILQCRALLEGGAPGVHFYTLNKSHATRTVLAAV
>A0A2C6B6X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. polymorphum|TrEMBL
MKIADIYKSKNLTTSFEVFPPNEKVGLEEVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHFTCIGSKKEEIDRVLEDLERNNIENILALRGDYPVDRELEPGD
FNYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVDAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A2K9PG26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii complex sp. CFNIH2|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGSGKPDMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPTA
>A0A2G2H6Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibacter sp|TrEMBL
MKVTEHITRAKGKTQFSFEILPPLKGQNVQSIFDNIDPLMEFKPPFIDVTYHREEYVYKE
LESGLIEKKIVRKRPGTVGICAAIQNKYSVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKSETYFKSEKEGHKFASELTSQIQDLNNGIYLDEELQNSSKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKKGATYIVTQMFFDNQKYFEFVKKCRAEGITVPIIPGLK
PISTKKQLNLLPHRFHVDLPQDLIIEIVKCKDNKEAREVGIEWCINQSRELIKAGVPLLH
YYSMGKSSNIYQIAKKVF
>A0A3D2K2K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHIREILNSNEPTFSFEFFPPKSAEAADKLYNVIRDLESYKPSFVSVTYGAGGSTRELTH
DLVVKIKETTEIPPIPHLTCVAHSEDEINTTLKRYASVGISNILTLRGDPPSSASNYDRS
GNAFYHA
>A0A5Y2QS52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. arizonae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1G5VFR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium qingshengii|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIASGAQFVQSQYCFDVPMFRAYMQKVRDLGYTEQCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKETPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A2A4M8W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDIHAEKQASGKPTISFEFFPFKTPEGEATFFGKTLPALMTAXPDYASVTYGAGGS
TREKTXEIVERIQNDFXLTTMAHLTCIKHTQAEIGGILDEAARRGIQNILALRGDPPPGE
EWAQTEGGFEFASELVEFLRERGGFGIGAAGFPEGHIDCAEGRETDWRHLVGKINCGADF
VITQMFFDNADYFRLADYLKGQGVAVPLFPGIIPVANAGQIKKFSAMCGAKLPESFSSRL
DELGDDADAVREYGIEYATGQCRELLERGAPGLHFYTLNKSKAVLQILANLGLA
>A0A4Q3SWV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIDHIRGAKDTLISFEILPPLKGKTINSIYDHLDPLMSFNPSFINVTYHRSEHVFKKK
ADGSFNKVEVRKRPGTVGICAAIMNHYKVDAVPHLICGGFNKRETEDALIDLNFIGVENV
LVLRGDAAKNEAVFEPEPDGNRNAFELLKQVNNLNNGIYLEDDIRDGFRTNFSIGVAGYP
EKHFEAPNLDTDLTYLKEKVDAGAEWIITQMFFDNSKFIEFVKRCRAAGITVPIIPGLKP
LTTKKQLTVLPRTFHVDLPNELITEVMKCKTDAEVEIVGTEWLLQQSRELKKEGVPVLHY
YTIG
>N8YTC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bereziniae NIPH 3|TrEMBL
MSKRIPISFEFFPTKTDAGAEKLKIVHQELQQFNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGDHFKIEVAAYPEMHPQAESYDADIQHFIEKVNAGANAAITQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVIKLCERLIAGGAPSLHFYTMNHTEPNRQLILDLGLA
>A0A011SII6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. MRS-1|TrEMBL
MTAPLRLREATRRCPKRMVHGPCGGVAIDGGCEVPGIRCSFVDDPAVLHDLEFSAAEVDA
PNAARASGDGLPVSPRGEASTAFAALVDADAVITADLPVRSTDPAVITEAGVRLRELTAV
IAGEPPGLRDALSLTHKALLLAAAGSRVVAGLTCRDRNRVALEGELAALADLGVSGVLAV
TGDHPASTALPQAQPVFDLDATRLTALARRAGLFVAVAEQPSAPPVDYRPVRLARKAQAG
AELGILNLCGDLAEIRRFTAALATTAAPVPVLVSVPVLTSVATARRLAALPGVGLPDELV
TAVAGADDPVDAGIAAAVAWARRALAIPGVVGIHLSAIAAAASAPTAGAADAAELAAVDA
LASAAARLRTAIATDAIAAETAGTA
>A0A3L7S2A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRLSQLFQDQQFVMSIEIFPPKTAEGDAALKRNLQTLIEYDPAFVSCTYGAGGSTQDRTA
FWCNEIQQTFHRTAMAHFTCVGATREELKDWLDKAAASGICNIMALRGDPPVGQEAFKAV
EGGLKNANQLVELIRETHPEMGIGVAGYPEKHIEAPDLEADLLNLKRKVDAGADAVFTQL
FFVNDNFFTFRDRCNKLGIQIPIVPGIMPITDFARIKRITSMCGTAFPADLAAKLEAVED
DASAQFEIGVEHAIQQCKQLIAEGIPGIHFYALNKSDACQRILDALQLPASKR
>A0A410H500|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenovibrio thermophilus|TrEMBL
MQSQQQYEQKLSLEFFPPRTEKGMEKLKTVIQELSPIQPEYMSVTYGAGGTTQSRTIDTV
RYIQTETDNEAAPHLTCIGASEESVLELLDTYEAMGIKRIVALRGDLPSGMMDPGEFKYA
SDLIAFIRRERGDTFKLEVAAYPETHPQARNCNIGIKWFKHKVEQGADSAITQYFYNVDS
YLYFIDNCERSGIDLPIVPGIMPITNYENLVRFSEGCGAEVPRWLKCRLESFEDDQESLL
AFGEDVVTELSQRLLDAGAPGLHFYSMNQSKPVLNIVSRLTFKDR
>A0A3D6CB83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
NAGIFREEDLKHTTKTRFCIGVAGYPEKHFEAPNMESDLRYLKAKVDAGADYIVTQMFFD
NKKYFAFVKACRDMGIEVPIIPGLKPIYTKKQLTTLPKTFHIDLPSDLSEAIQHCKTDDE
VEKVGTEWLLQQSVELKKAGVPVLHYYTLGRPHIVANVVKDLV
>A0A3C1T5R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
LKPIYSLNQLTTLPKVFHIDLPVALSSEILKCKTPEAIEQVGTEWLLAQSQELKKAGVPI
LHYYTLGRPHIVGNVVKQLL
>A0A0P8YQS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinosulfonomonas sp. PRT-SC04|TrEMBL
MVTPRISFEFFPPQSLEASFRLWDTVQVLAPLDPNFVSVTYGAGGTTRELTHDAVTLLHK
QYGLKVAAHLTCVNSSRDEILTIANGYAEAGVTDIVALRGDAPKGRDSFDAQGDGFATSI
ELIETLANTGKFNIRVGAYPEPHPDSANTAADVDWLKRKIDAGASSAITQFFFEADTFFR
FRDACQKAGIDAPIIPGIMPITSWTGLKKFSASCGTTLPAWLDDAFTTAIRDDRTALLST
AVCTELCTDLIDGGVEDLHFYTLNRPELTRDVCHALGVTPNVTLENVA
>A0A8F8TZX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus amyloliquefaciens|TrEMBL
MGLLQDLKERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIADLGADITGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTEKEVKIRREEEVI
SVSNERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
QKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A524DMD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAEKKIYSKLGEMISKGEFVLTGELEPEKTCDLSHTIQEAKEMAPYVVAANVTDSPLAIV
TINSMAASHIIQRETGLECVWQLTVRDCNKIGLAGQIMGAQALGLRNVLSLTGDHTNLGD
VPEAKPVFDLDSATLVKLVREMVDTGKINDNEIEHPPTMHVGAAANPNADPMEAEILKIG
RKAEAGAEFIQTQVVYDLDMTIEFLRAIQKYKVPVFLGIFPMKSYGIAKGFDMFVPGVDV
PKDILAKWKSVKTNVSDKKEQKDTYDQLNYEFFKPFISELKSKNLLNGVHCMAVHYTRIF
PKLNKVIKG
>A0A5C9E110|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAEKRVYSKLGKALADGEFVLTGELEPEKTCDLSHTIKEAKEMAPYVHAANVTDSPLGIV
TINSMAASHIIQREADLEVVWQMTVRDVNKLGIAGMIMGAEALGINNILSLTGDHTAMGD
VPESKPVFDLDSATLVQLVREMVDKGSINGHEIESPPKMHVGAAANPNADPMGAEVLKIG
RKAEAGVEFIQTQVVYDIDKTIEFLREIKKYDVPVFLGIFPMKSYGMAKGFDTFVPGVDV
PKDILARWKDVKKNTTDKKEKKAKYDQLNYEFFNPFITELKKKDLLAGVHCMAVHYTRIF
PKLVEVIKA
>A0A6B3TS21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neobacillus thermocopriae|TrEMBL
MSFLEKLKNQILIADGAMGTLLYSYGTDCCFEELNLSHPEQIQHIHQAYIDAGADVIQTN
TYAANYLKLSRYGLEDSVKDINSAAVHHAKKVAKNRAFILGTIGGNRGIKPNSISLEEIK
RSFREQLYCLLLEEVDGLLLETFYDLEELETVLAIARKETKLPIIAQVSIQEPGFLQNRT
PVNEALKRLESIGADVVGLNCRVGPHHMLLTLEQIELPKQAYLSAYPNASLPAYTDGKFH
YDSDADYFRRAANEFRKQGVRLIGGCCGTTPEHIRMFAAELKNKTPIKEKIVKFTPKVTV
VEDPTIKREHTPLQEIVKQRPSVIVELDPPRKLDTRKFFDGAKALKEAGIDAITLADNSL
AQVRISNESLGYLIKQELGIRPLIHISCRDRNIIGLQSHLMGLHTLGMHDVLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTAFSIAGAFNPNVRSIEKAVK
RLEKKMDCGADYFISQPIFSEEKLLEVYEHTKHLKAPIYIGLMPLTSSRNAEFLHNEVPG
IKIADSIRERMAKLNDQPNLAAREGVEITKSLIDAALDLFNGIYLITPFLRYELTLELAL
YARQRAQELRGNIHAKTTIY
>A0A524EEA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAKRPAYSKLCKALADGHFVFTGELEPKKILADGMEEVIESAKEMKKTGRIIAANVTDGP
QGDAYMCSLVPSFVVQRDAGIEAVWQVAVRDRNRVALFGDILGGALLGLKNILVLTGDHT
ALGDNKQGRISYDLDSTQFCELLKKMIDEGTDYAGNEITDGKIEMNYGCVANPNAVGEYM
EPEILKVGRKVEQRVDFIQTQTAFDIDVAKNFINELARYNVPILLGVFPMKSYGIAWYFD
KYIPGVSVPKDLLDALKKAEKDNKGDKQGKYAALDKVNVEFFVPFIEEIKKSSKASGIHC
MAVEYERLFAPLLNKSPDYAKKYY
>A0A8H5Q7B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella subglutinans|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVRHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSESPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMTSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFGLLKGLEVKDLTTPATPLTESV
GNGAGDTEPIVNGTAATAVAN
>A0A846MMI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermonema lapsum|TrEMBL
MKIVDYLRNPEKTLFSFEVLPPMKGQSIQELFDTIDQLMEFGPKFVNVTYHREEFVYKKR
PDGLLERKTTRKRPGTVGICAAILHRYGVEPVPHLICGGFTKEETENALIDLHYLGIHNL
LVLRGDPIPTEKVFTPEPGGHRYAVELLEQVVNMNRGIYLEEEIENAVPTDFCIGVAGYP
EKHYEAPNLQSDLRYLKMKVDKGADYIVTQMFFDNRKYFDFVEKCRAIGINVPIVPGLKP
LTSKRQLTMIPRVFHVELPEELVKEVEKCSSDEQVKEVGVEWCIAQSKELMQHKVPCLHY
YSMSKAASVRKVAEALF
>A0A6N7YPD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis pithecellobii|TrEMBL
MPFKRTEDEVVAHVPLDIPVTITVTEAKGISATIDLAERLAAHGYHVNPHLPARQIGSEA
ELVDIVNRMLANGIDRAFIVAGDAKEPAGDYDSALKLIQALDHMGRPLSDIGVSGYPEGH
AHISDADLDTALRTKTPYAARIVTQMCFDATTIARWADATAQRGITVPVIVGLPGPVSRQ
KLVRIAGGIGLGQSARFLQKQQGLLRKFLTPGGFTPDGLLRKLAALPTASAGNIQGLRIF
TFNEIAGTEEWRRNLAASLPGALGEPCPPAQRVSAQ
>A0A5Y1WLA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae|TrEMBL
MSFFHANQREALNQSLAEIQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1Q7GXU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_40CM_65_14|TrEMBL
MQSFREAIEDRVLVCDGAMGTMLYAKGVFINKSFDALNVAQPDLVAEVHQEYVRAGADII
ETNTFGANRIKLGSFGLADKLHAINEQGAKIARHAADDRAYVAGAIGPLGIRIEPWGKTG
VDEAREYFREQAQALLDGGVDLFILETFRDLNEIGAAIDAVRSISDLPIVAQMTTEEDGN
TLDGTPPERFAPELEKRGATIVGVNCAVGPAPMLDTIERIAAVTPLKLSAQPNAGKPRDV
EGRNIYLCSPEYMASYARRFILHNVRVVGGCCGTTPDHIRQIKTAVRSLAPGLVRGASRA
EPPAESGGAKAGGVSRATVSAAIASPPIAREHKSRLAHAMAKGTFVVAVELLPPRGYRAD
DVIERARQLKIQGVDAVNIPDGLRGGARVSALSLAVLIEQQAGIETLLHYSCRDRNLLGI
QSDLLGAHAMGLRNLMLITGDPGRVGDYPDATAVFDVDSIGLTNVVSRLNRGCDVGGQAI
GAPTGFHIGVSVNPAASNLDQELRRFEYKVEAGAEFIVTRPIFDVAAFERFLTRIEFARL
PVVAGLFPFESARNAEFMANEVPGVRVPDAMLERMRRAEGAETAAREGIAIAREIAASLR
SAVQGVQIATASGDIDAALAVLDGLR
>A0A4Q3PY38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MTTTTTTSKTAAPAPSAARSGTFPVSFEFFPPKTPEGAEKLRTVRQQLYTRRPEFCSVTY
GAGGSTQEGTFSTVREILSEGVSAASHFSCIGATQETVRTQLAQLKAMGVTRLVALRGDL
PSGYGAGGEFHYASDLVAFIRAETGNDFHIEVAAYPEVHPQARSPEADLQAYAAKVRAGA
DSAITQ
>A0A1I1XI71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas sp. Nm166|TrEMBL
MESQKKFSPTFSFELFPPQTLQGIEKLRLTRKQLAQFCPKFFSVTFGAGGSTRERTLETV
LEIQAEGHVVAPHLSCIGSTQENIRTILEKYYQAGIRHIVALRGDLPSGMAQAGEFRYAS
ELVAFIRQEFGSLFHIDVAAYPEYHPQARSAQADFENFKHKIETGANSAITQYFYNADAY
YHFVALCESAGLNIPIVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLEGYNDDHASIQA
FGLDIVTDLCERLLKAGAPGLHFYTLNSADLTSLIWQRLNLKKDTD
>A0A177CBG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraphaeosphaeria sporulosa|TrEMBL
MEKITDKINALPGGANYFSLEFFPPKTAMGFANLSSRLERMAQALRPLFVNVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRKLVDEALEHARALGIRNILALRGDAPRSEE
YRDEGQLPEDDSNKDFTWAVDLVRYIRKQYGDYFCIGVAAYPEGHSDQSHPEAQDPKFDL
PYLVEKTQAGADFLMTQLFFDVDAYDKFETMLREHESGAFTTIPIIPGLLPIQSYQILNR
VSKLSHARIPADIVARLDAVKGDDELVKQVGIKVLSEIVDHLKARPSPTRRGFHFYTLNL
EKAVSHIVESCHLIPQPLDDDDDAIELTPGADLQPPEGALRTKDRRRLSSVNSDPRNRVI
ISKSSHSKSSNASYGVPEDEAGIPQGPVTTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVDKDDISKLFRRHIEGDLEAIPWSEQGLSP
ETSTIAKELLALNAKGWWTVASQPAVNGLKSTDPVFGWGPKNGLVFQKPFVEFFLPAADW
AKLQPRLQAHDQVTYFASNAAGDFEASNEEGVNPVTWGSFTGKEIVTPTIIEAVSFRSWC
EEAWSIWREWQRIYAPRTETSKLLGEMRRDLWLVNIIWGDYVEGEGLWRFLMEE
>J3S088|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crotalus adamanteus|TrEMBL
MVNESHGELSPVSNGLGGTRLDGGSSSSSSGESSQNSSRCSTPILDTERHERLREKMRRR
QESGDKWFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMM
ATTALNYCGLETILHMTCCNQSRGTITAHLQKAKRLGLKNIMALRGDPFGEEWEEELEGF
NHAVDLVKHIRQEFDDYFDLCVAGYPGGHPEAESYEEDLKHLKEKVSAGADFVITQLFFR
TETFLKFLRDCQDIGISCPVVPGIFPIQGYHSLRQLVKLSKLVVPQEIKDVIEPIKDNDA
AIRNYGIELAFKMCRELLDSGLVHGLHFYTLNREVATLEILRRLGLWKEDPRRPLPWAIS
AHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKS
PREELLKMWGEELSSEESVYEVFRCYIAGEPNRNGHKVTCLPWNDDPLAAETNLMKDELV
KVNRRGILTINSQPSINGKPSTDPIVGWGPEGGYVFQKAYLEFFTSAENIKALLTVLKKY
GQRVNYHIVNVKGENVTNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWI
EQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPIESCLWQVLEDTYEQLNSPGEEQRT
SGL
>A0A1M7G0W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium xinjiangense|TrEMBL
MKVTQHIEAAKGDTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVD
KGNGLLDKRLTRMRPGTLGICASIKHKYNVDTIPHVLCGGFTKEETEYLLVDCHYLGLDN
VMALRGDAMKDEQYFMPKKGGNDFAVDLVKQIYQLNQGKYLHDVMEVDNKANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIQAVDQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>R1GLW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryosphaeria parva (strain UCR-NP2)|TrEMBL
MEKITDKLAALPQDGRYFSLEFFPPKTQMGFANLQNRLERMASALRPLFVTVTWGAGGST
ASKSLELAELTQRQLGLTTCLHLTCTNMSRALVDDALEQAKALGVRNILALRGDPPRSDE
YREGEADQDNDSNKDFTWAADLVRYIRKQYGDYFCIGVAAYPEGHSDQSHPDKQDPKFDL
PYLIEKTKAGADFIMTQLFFDIHAYEDFENMLRNDPSGVFKTIPIVPGLMPIQSYQILRR
TTKLSHAKLPPDMLARLDTVKGDDEAVKNVGVDILSEIIEEIKKRPSPGPRGFHFYTLNL
EKAVAHIVERCRLILSVAPDESVEEAVTIDDIPVNGGGPTDSLKVKDRRRLSSANSTPHN
RVVVDRPSTSSNKSYEALADEAGVPKDKIMTRANTLAISEGEGSLGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHVSIPQAIRLWKYPTTVEDISDIFRRHILGELEAIPWSEEGLN
AETETIRDQLLKLIGKGWWSVASQPAVNGVKSTDAIFGWGPKNGYVFQKPFVEFFLSSAD
WKKLQAKLDELSDVTYFAGTNGGDFSSNDEDSVNPVTWGSFAGKEIVTPTIIESVSFRAW
LEEAFSIWSEWRHIYPPRSATASLLGRIRDDYWLVNIIHHDFVEKDALWRLLLED
>A0A0C3HJH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oidiodendron maius Zn|TrEMBL
MHIKDMLSDDAKVGRPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPNFIDITWGAGGRLA
QLTCEMVNVAQSQYGLETCMHLTCTDMGKDKVDEALGNAYKAGCTNILALRGDPPREKEK
WVATEDGFQYAKDLVKHIRDTYGNHFDIGVAGYPEGCDDQDDLELLMDHLKEKVDAGATF
IVTQMFYDVDNFIEWVGKVRAKGITIPIIPGIMPINTYASFLRRCNHMGCKIPPEWSAAL
EEVKNDDAAVRNIGTGLVATMCRRILEAGIHHLHFYTMNLAQATQMVLGELGLMPSTERP
RKQALPWRQSLGLGRREEDVRPIFWKNRNKSYVTRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNRKLWGEPKSIKDIADVFVKYLEHGVEALPWSEAPITSEADSIKVDLIS
LNKRGLLTINSQPAIDGVRSSDPVYGWGPTNGYVYQKAYLELLVPPSLMSALIGRIEKDP
DLTYYAVNKAGNLMTNSLGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGEDW
AKCHDASSPSRVLIESLMESWYLVNIVHNDFHQTHGLFPLFDGLEVEDLTKEVQVPQTNG
NHSASNGVDSRPLTNGTAVSH
>A0A221SWB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus ficus|TrEMBL
MTSGSRVSVELVPRSRSGLRREIAQVAEHLPSVDTINVPEFLRYSTRSWEGAAFARPRFR
GIPHVRAIDLNPREPLPMCGPLVAHGMDELLVVSGDPPADMSHRVYNVDAEQAIRRVARE
LPHVRVYAGLDPYRQSFARERDYLERKLEAGAVGFFSQPFFDLRLMDAYADLIPDGVEMW
WGATSVLSEGSYTYWESRNHAVFPRAFRPTLEWNRQFAADLLQFARDRGHHAYFMPIKTD
VVEYLGGIL
>A0A6D2GEI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7V2SJP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MLEQKLNRGDFVITAEIVPPLSGNGDDLIQRAAPLAGLVDAVNLTDGAGARLAMSSLSAS
ALLVREGFEPVLQITCRDRNKIALASDLLGASALGIKNLLILHGDDPSKGDIPDAKPVFD
LDSKTLIEMAADIQTVLGKDARTITAPPVFHIGCADAPRDPAPDWKPDSLGAKIAAGAQF
AQTQFCFDVDIAKRYFLHLADHGITDRLKFIVGVGPLLSAKQAQYMNDNLFGVTIPADII
ARMEAADDQKAEGRKICAEIVSGLRDIHGISGVHIMAPMQSGSAIAQTIKAIQAF
>A0A7W1SN83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVIEHIKQSKSTLFSFEILPPLKGKSIQSIYEGIDPLIEFNPSFINVTYHREEYVYKKR
EKGYLEKVSIRKRPGTVGICAAIINKYKIDTVPHLICGGFTKEETENALIDLHFLGVDNI
LALRGDPVKTEPHFIPTENGHAYAIDIVKQIVNMNKGIYMDEELELAAPTDFCIGVAGYP
EKHFEAMNLKTDLLNLKRKVDAGADYVVTQMFFDNIKYFDFVENCRKMDINVPIIPGLKP
ITTLKQINFLPKMFNIDLPDDFADELLKCKTDKEVYQIGVEWAIQQSKELINAGVPCMHY
YTMGKSDAVRKIAKEVF
>A0A7G2SGZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp|TrEMBL
MMSSLSECLDQKQFCILVEYLCSVKSPLAVRKTLANFPAMMTLADRVHADNDPAPLDLAT
KYPDTVDKLIHFSGKARDIKDLERFLNDLENTTIRNLLLVTGDKLKSHDFGYEVAAQRTR
YLESVSAIMAAKQRQIFKIGVAFNPFKYTEAESDAQYLKLHKKIKAGADFLITQLGFDVE
CLQQTQVFLQKNYPNFSALACVMPLTLKRAQFMVKNRVAGIVISDHVLQTLEKEYQSDPI
QAEINVYARCALQILICKHFGYAGVHLSACHKEDEQKKLEQALKVFENFSLNECQQAWKD
LWQADAQGDFKPNVKISSKPVTQTQILKYKKMHTMHRMFFESKMARTIGHFVFKPSFWNR
SNAQNILLKIEHSSKHRLVGCESCGECRLGDTLYICPETCPKGLANGPCGGTSLDRCEFE
DRECIHSVKARLAKKIHQTEILKTKLIPAISITTRHTSSWKSWFTDTK
>A0A7J5V413|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKHLLKVPEHIAAANRTLFSFELLPPLKGQNIDNIQNTIDPLMAFEPAFVNVTYHQEEFA
YKTLPNGLIEKKTIRKRPGTVGIAAAILYRYGVNVVPHIICGGFTREETENALIDLHFLG
VKNLLVVRGDPQPSVKYFQPEPGGHTHSVELVQQISNLNKGIYLEEDLLNTTPTDFSIGV
AGYPEKHIEAPNLETDLHFLKKKIQAGAEYIVTQMFFDNNKYFDFVDRCRTAGITVPIIP
GLKPISTIGQMYTLPQTFNIDLPEPLVKELLKCTDNKQAKEVGAEWAVQQCKELVSHNTP
VIHFYTMGKADTIVKIAKQVF
>A0A1D8C221|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoalloteichus hymeniacidonis|TrEMBL
MTRVVDRLRAQRPVFSVEFFPPRDDESERQLWRTIRELEPLDPAFVSITYGAGGSSRDRT
IRTTGRIAQETTLVPMAHLTGVDHSLAELRNVIGWYAAVGVHNVLAVRGDPPGDPMGEWL
PHPEGITYAEELVRLVRELGPFCIGVAAFPYGHPRSADLEVDADHLVRKIEAGADFAIAQ
LFFEPDDFLRLRDRLAARGCDVPLLPGVMPLTTMRTLRKTVELSGADVPPFLAKRLERFA
DDPRGFRAEGIEVVTELCSKLLAEGVDALHFYTLNRSPATREVVGRLGLLPARS
>A0A7M2B9N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. JNUCC-42|TrEMBL
MGKRDLRAYLTQHLLVGDGAMATQLYEQGVPIGVSYEELCLSNPQVIRNVHAAYYEAGAR
LIETNTFGANRDSLSRYGLESKVTRMNRAAVTIAREAVGDDAFVVGAMGSIIAGRVRNKQ
IEQYRDQFEEQATSLLHAGVDGILLETFLDVDELLLALDVIRPITQLPIIAQLATLEVGT
TRDGHMLTSAFQLIKDAGADVIGLNCRLGPAEILRSFEATVCPNDVYLSAFPNAGRLGMA
DGTLSYKSSPEYFAESAVRLREQGVRLIGGCCGTTPEHTRAIAEKLAGVTPLPRVNPQAP
IHSETITVPAVQQRLQPSIIDQVKDHPTIIVEFDPPKDLHTEDFLHGCCALHEAGANAVT
LADNSLATVRMSNMALGAMMKRLGVEPLLHIACRDRNLIGQQSHLMGLHALGIDQVLVIT
GDPSRFGDLPGASSVYDVSSFDLIRMVKQLNQGFAFSGKQLKQNAQFIVGAAFNPHVRHL
DAAVARLEKKVEAGADYIMTQPVYDAETIVHIYEATKHIHVPIFIGIMPLTSLRNAEFLH
NEVPGIKLSTYALEQMKLFTGEAARQEGNRMAKELIDVTLQYFNGIYLITPFNYYQMTVE
LTQYIRQQEQVKAGYKQVSSSS
>A0A8J6P012|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thiopontia autotrophica|TrEMBL
MNQSAPQFSLEFFPPKTEAGREKLQTAQKELFSTIQPAYASVTFGAGGSTQEGTYDAVME
IQQQGVDAAPHLSCIGATKDSITAILRGYQEKGIHRIVALRGDMPSGMGASGDFRYANEL
VSFIREESGDHFHIEVAAYPEFHPQAPDAFTDLQNFKRKVDAGADSAITQYFYNIDGYLR
FGEDCAAMGLDLPIVPGIMPITNYTNLARFSEMCGAEIPRWIKERLIAYRDDTESLRAFG
LEVTTRLSQDLLSAGAPGLHFYTMNQSAPTLQVFNNLN
>A0A7W2C2F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MTKTERPITRTSELKISFEFFPPKSPDMEAQLWQTVEALQPYQPDFVSVTYGAGGTTREP
TLSTVKRLIDDTPLATASHLTCVGATRDEVRAVVEEFEAAGVRHFVALRGDPQGGVGTRY
APHPGGYVNAADLVSGLRAMGDFEISVSAYPERHPESENDTVDLDMLKQKVDAGATRALT
QFFFDNDVYERYMERVQAAGINIPIVPGIMPIQNLTQLKRFASMCGASIPSFLDARFEGS
EGDAQARAAIAADLAAEQIADLSRRGVQEFHIYTMNRAPLTIATLDRLGVSPKAGRVSGA
AA
>A0A3D2S961|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTERIHQATSTLLSFEVLPPLKGKSVQSIYDILDPLMTFNPAFVNVTYHRSEYMYKKR
SEGIFEKIYTRKRPGTVGICAAIQFKYKVDAVAHLICGGFTKEDTEDALVDLWFLDIENV
LLLRGDAARNERVFEPEPGGHAHAIDLVKQVVNMNKGLYLEEEHQGGKTDFNIGIAGYPE
KHFESPNMSTDLKVLKEKVDAGAHYIVTQMFFDNQKFFAFEKKCREAGIHVPIIPGLKPL
TAAAQINTIPRIFHVDIPEALADAVEKAGSAEAVQKVGTDWCVEQSRELKAAGVPCLHYY
TMGKIDVMRSIMQE
>I5C7K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor aquibiodomus RA22|TrEMBL
MTRRPPQIDENPDGVDLPLEPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANAQDVYER
AAIFDGWVDGINAVDASGANCHMSSMGICALLTRMGYATIMQIACRDRNRIAIQGDVLGA
AAMGVGNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDEEKFLSGRRLTTPPAV
FLGAAINPFAPPFDFRPHRLAKKIAAGAQFVQSQYCYDVPMLKEYMKRVRDMGLDEKCFI
LVGVGPLASAKTARWIRSNVPGVHIPDAVITRLEGAEKQKEEGKRLCIDIINEVKEIEGV
SGIHVMAYRQEEFVAEIVHESGVLKSRKPWKREPGLDDALVAERLDHILHDDPSEKPVEM
VRDASATSSE
>A0A4P5TQN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHIAQAKNTLFSFEILPPLKGVGIQSIYNTLDPLMEFKPPFINVTYHRSEFIFRKT
AEGLFEKKIVRKRPGTAGICAAIMTKYSIDAVPHLICGGFSIDETEDLLIELDFLGINNV
LLIRGDKMKSEEVFSSQKDGHKNALDLVHQAVKMNKGIYLEEELNNAMPTDFCIGVAGYP
EKHYEAPNMNIDLQNLKAKVDAGAHYIVTQMFFNNQKFFEFVKSCRDIGITVPIIPGLKP
ITTKKQISNLPRIFNVDIPSELIHEFDKCNSDADIKNVGIEWTIQQCKELINAKAPVIHF
YTMSNSESVKNIVKNLS
>A0A1U8H097|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum annuum|TrEMBL
MKVIEKIQESIKDDKVVFSFEFFPPKTEDGVDNLFERMERMVSHNPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALENIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGLATPEAYEKDLAYLK
QKVDAGADLIVTQLFYDTDNFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKIMASGIKTLHLYTLNMEKSALAILMNL
GFIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDEFPHGRWSNAQNP
SYGALSDYQFMRARSRDKKLQEEWAVALNSVEDIYERFMNYCLGKLRSCPWSELDGLQAE
TKIIDEHLSNINTKGFLTINSQPAVNGAKSDAPLVGWGGPGGYVYQKAYLEFFCSREKLT
TVVEKCKAFPFLTYMAVNKQGNFISNIHQIDVNAVTWGVFPAKEIVQPTIVDPVSFMVWK
DEAFEIWSRGWAQLYPENDPSRKLLEQVQNSYFLVSLVDNDYINGDLFAIFKDI
>A0A3A0E7T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MIPSHPHQGRPPHPDENPAGPHLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADP
EDVYERARIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQ
GDVLGAAAMGVMNILCLTGDGVQAGDQPGAKPVFDLDCMSLLQTVRTMRDEARFLSGRNL
TTPPAVFLGAAINPFAPPYDFRPLRLAKKIAAGAQFVQSQYCFDVAMFRDYMARVRDLGL
HESCFILCGVGPLASARTARWMRSNVPGVHIPDAVVARLEGAADQKQEGKRLCIDIIDEV
KEIEGVAGIHVMAYRQEEYVAEIVHESGVLKGRRPWRREPRPDDALVAERLDHILHDAPV
ESPQEIVRDVTQ
>A0A523GJP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKITEHLNKAKGTLFSIEILPPLKGQSIQVLFDHLDPLMEFNPPFVDVTYHREEYVYKDR
GHGLLEKRSIKKRPGTVGICSAIKNKYNVDTVPHIICGGFTREETENALIDLNFLDIHNV
LLIRGDAIKFEGAFQPEELGNHYGIELVDQVVNMNNGKYLDEDLIKPTPTDFCIGVAGYP
EKHFEAPNLMFDLHYLKRKVESGAQYVVTQMFFDNQKYFDFVNKCREMGIDVPIIPGLKP
ITIKRQNTILPRIFHIDIPEALSDEIEKCKDNDQVKEVGVEWAVQQSKELMDFGVPCLHY
YSMGKAEPVRKIASALF
>A0A2T5VBB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Breoghania corrubedonensis|TrEMBL
MTEIRSETFAKAQNATAPRRLPLWLRGWSVEATMPEKAQIAALEGVLEPGCEIYLSSLPR
IQLEDQLAAAVAVHEAGFVPVLHLAARKFVSEQQLADHLGAAGERAGVRKCLVIAGDLDV
ARGPFGSSLDLIDSSAFARSSVVEVGVGGYPEGHPFVGEESLAQSLATKVETARAAGMVP
YVVSQFCFDSVRILHWLGWLRTFEPTLPVKLGVAGPIGAATLMKIALRCWVDVPSSGVRA
VPQLVQKGAPDRIVGELDAGLKALHEQGALQLHLYTFGAIERTARWARAAQTTVELAYEM
>A0A4D6YAH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MNIPSVYHKDIINQKLENIRNSVECSFEFFPPKNSSLEKNLWCSVKRLSALKPKFFSVTY
GANAGEREKTYNVVKKIQEKTGIVTAAHLTCIDSTPDKLEKIAKNYWNNGIKSIVALRGD
TSEKNYKHTMYALDLVILLKKIADFDISVAAYPELHPESKNSKLDIINLKEKIDAGASRA
ITQFFFNIDSYLRFRENCIKNKINVEIIPGILPVCNFKQLQRFSNMTNVQIPKWMFEIFN
GLDNDIVTQKIIGSSIAIDMVKKLSSEGVKNFHFYTLNESDITYSICHILGL
>A0A3M1JDQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTDYFKQAQGQTLISFEVLPPLKGGRMQDIFDTLDPLMEFKPPFIDVTYHREEFIYKR
RPSGYYEKTAIRKRPGTVGICAALMHRYGVDAVPHLICGGFTVEDTENALIDLHFLNINN
VLALRGDARKFEGKFVPEPGGHAYALDLVRQIQNMNNAKYLDENIDDGEPTDFCIGIAGY
PEKHFEAPNMEIDLQYTKAKIEAGADYIVTQMFFDNQKYFDYVKACRAAGIDVPIVPGLK
PLTKLYQLNSIPRLFHVDLPGDLVSALQAAKTPDARRQVGIEWCIAQSKELKAAGVPCLH
YYMMGDSSTVRQIAEAVY
>F7YXH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudothermotoga thermarum DSM 5069|TrEMBL
MKVVEKIKQKRILSIEVLPPSRGQNVEEIYQVIDNLLDFDIDFINVTRHAAEVTYVETPE
GIVKVPKVKRPGTVGLTAALMKRYGIDVVPHVICYGMNKYQIEELLIDLQLIGVENVFVI
RGEYENRNIQPDQSSYKYAVELVQQIARMNKGESVLPGEEGFKTDFCIGVAAYPEKHYEA
PNLEEDLRHFKEKFEAGAQYAITQMVFDFEVYKRFIEMTKEMGINIPIIPGIKPIVSLKS
IYQIPRKFFVTIPNDFVQKMQEAKTPKEEFLIGTKYMASLVEKLLSYGVPGIHIFTMGRG
QSSRALLEAVYGKERRRD
>A0A1W9MNJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon A3|TrEMBL
TNYENKNLNAKTNFFIGASLSPTSSPLDGEIYKVKRKLIAGVDFFQTQGVFSIDPITNFL
NLYEKMMGEKISDKVLVGIVPIWSYGMFKYLLTLPGIVVGEKFLNEVNEARKKQKETGQK
GLIEEAGVNLCVDLVDKIKGIGVKGVHIMPVGNLHAMKKIMDKSGL
>A0A7G6Y5U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia shinshuensis|TrEMBL
MDCTDARFSFELYPPRNERAAAALPATIDRLAAAGPDFISVTYGANGSSRSSSLEVLRYI
LEHTDVSPMAHLTCVGSTHTEANRLIREFLDAGIRRFLAVRGDPPAGLAPGDDGLGDIKS
SSELVQLIHRVQAERVPYDALPVPGLHAQAVLSHREHVQIAVAAFPHGHPSRSVSQDIDA
LLAKQAAGANLGITQLFFHAEDYLSFAQKAREAGVTFPILPGIMPVTSPARLARMLELSG
EDLPSDLAIQLEVEPDDEGRRELGIEWTARLAQRLLDGGAPGIHLYTFNQHTAVLSVLER
VGLLDPTNATTATTTAATSQKAGDPA
>A0A233STU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces diastatochromogenes|TrEMBL
MNPTATVPPAVGTSLLDDFSLEMTGKDVPKLEEAHAGIPRGTRINVTFLAGEDPGMRFAA
ARAVKRLGFVPVPHISARRLPSQRHLEEFLAGLAADGTAENVFVVGGDPARPEGPYEDAL
AVIRTGLLQRHGVRHVGISGYPEGHPAITEHSLWSALGDKSAVLGAQRIAGDVITQFGFD
ADRVLGWVEDVRARGVGLPVRIGVPGPAGVRRLMTYATRFGVGTSASIARKYGFSLTNLM
GTAGPDRFLHALAQGYDPARHGEVKVHFYTFGGLRATVEWIARFRRGDREG
>C6M5N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria sicca ATCC 29256|TrEMBL
MNRDKHNGNHIKIIHKLSENFEFDSYTRQIYHTSLKTFKKDNRGTQPMSYAKEINALNNS
LSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGANSGERDRTHSIVK
RIQQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEPPGYEKKPFYAEDL
VKLLRSVANFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVITQFFFDVERYLRFR
DRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGLDDDQATRNLVAAS
IAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>D9QIV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas subvibrioides (strain ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81)|TrEMBL
MDMLKDADAPTASATGRMLRHFSLEMTAKDVPSLEEAARFIPQGTRIAIAFLPGETFEAR
LHAAVRVRALGFDPAPHISARRIASETELRTFLERLAADAGIKRLFVVAGDPPVPEGPYE
DALSLIRSGMLAGLNLESVGVSGYPEGHPDIDGDKLWRAMFDKRDALGELGISMTILTQF
GFDPDPIVDWIAQVRAHGIDALIRIGVPGPAGIKTLMRFAARCGVGTSAKVMSRYGLSIT
QLIGSAGPDRLIGDLAARIDPVRHGDLSLHFYPFGGIAKTAEWVSDYAAKHGN
>A0A833JSG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter nauticus|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQVVRDQLAEVNPDFFSVTFGAGGSTRDRTIETV
LDLHKQGISTAPHLSCVGGTRAEIGELLDLYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIRNHSGDHFNLEVAAYPEFHPQARSAEDDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A6J4XRU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis Delta 1 endosymbiont|TrEMBL
MIRSITQKKSQEEIERLLQGLNRIFIIGCGTCTTLTRTGGEPEVRALKQELSEKGKLITG
TTVVPVACDNLTREFLNEFGEQVKQSDTLLITSCAFGVQTIARQLNKMVVPALDTLFIGK
ESAFGTFDEVCTQCGTCIIGETGGICPVTNCHKGLVNGPCGGTNHGKCEIDVNKDCVWTL
IYNRLDELGRLESMRTYQKPRNHLGEPKPGKIKLTDA
>A0A347U5D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter ellisii|TrEMBL
MFETLIQKLQEDKYLTLETTPQHEPSMHNIIERIKKFKLQDRVDGFSCTDNPLAKLKYNA
LFAALKLQMEFNKPVIATMSMRDRNKIALQSDLMGANDFDVRAILALTGDPAKMSDQPHA
KGVFEANSLMLLKIIKSFNYGMDMSGHPFKIEPKQIFPFAVTNSYAKNFSSLEKKMHLKI
QNGAMGIISQPVFDIENAKKLLESFNIAKEGVEGDKQKAQLIFGIFPVTKLRTALFLSAQ
VPGIHVPQFWIDALEAAHNISEEEEYKVGMQLSQNLFKELNKLHPKIHLMTANRFDVANE
IIS
>A0A2H0MTM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium CG11_big_fil_rev_8_21_14_0_20_45_15|TrEMBL
MKIKEILNTKRPVFSFEFFPPKDSAGFESLFQTIESLKPLAPAFVSVTYGAGGSSRHKTI
DLVGRIKNDVGIEAMAHLTCVGHSRDEIGEVLKELEAKGIENVLALRGDPPQGQEHFVAH
ENGFKYANELTEFIKHNYSFCLGVAGYPEVHPESSNPVSDIENLKRKVSAGADFIITQLF
FNNDHYFDFVTRVRAAGITVPVIPGIMPILNLKQTIRFTQMCQAEIPVDLMNKMEAVKDD
TEAVKQIGIDHAAQQCRNLLDGGAPGIHFYTLNRSNATLAIMETLKSDFL
>A0A1T5HWR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium piscicola|TrEMBL
MVNQASATNAESELRVRYNDITRGVYFIGTTPPKTNTPLDEVEGIADRLVNRIKDLAIDG
LIVYDIQDEVSRTKKPRPFPFKSTHDPRYYSSLLNKKTGCPVITYKSVVQSETEAFDEWL
NEAWHEYQVRDIVLVGSPSAKNEVSLPLSTAYQALAEHQNNFFTGGIMIAERHAKKGNEH
ARLIEKYQQGCNFFISQAIYDTQATIDILTRYAIECKQDGIKPQRILLTFSPCGSAKTLE
FIEWLGVSVPEATSLRILNATNPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRK
EEIDGSILLYKLLRASMDSHLAKHEFRTLQAKASASIALI
>A0A2M7H058|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium (Candidatus Ratteibacteria) CG15_BIG_FIL_POST_REV_8_21_14_020_41_12|TrEMBL
MSKLSEALEGKKFVVTSEIGPPKGTNIEKCLEDAELLRDKVSAINVTDIQSAVMRIGSLA
ICHLLAEKGLEPVFQMVCRDRNRLALQSDLLSAWVLGIKNVLCLTGDYTSLGDHPETKPV
FDLDSVQLLKTVATLNQGHDIAGHELDGTPNFFAGAVVTPGCDPLEPQIIKMKKKIDAGA
KFFQTQSVFEPKKFESFMNDVEKFQVPVMAGIVVLKSAGMAKFMNENVAGVFVPEEIVKE
MAETKKEDRRKKAVEIAARIIREIKPICQGAHIMPLGWDALVPEIINQAELS
>A0A017N2J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis str. S23L17|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A4X2MC19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vombatus ursinus|TrEMBL
MAELPYMSHPRGRVRPHGHCSWSLGKGSQKTGSLYFSVPSSISCRNPAMANEARSSSSLE
GSSSGSEGSKDSSRCSTPVLDAERHERLREKMHRRMESGDKWFSLEFFPPRTAQGAVNLI
SRFDRMGAGGPLFVDVTWHPAGDPGADKVTSSMIIANTAVDYCGLETVLHMTCCHQTQDE
ITSHLHKAKRLGLKNILALRGDPMGDEWEDEENGFCHAVDLVKHIRSEFGDYFDICVAGY
PKGHPEAASFEEDLQHLKEKVSAGADFIITQLFFQVDTFLNFVKACTAIGITCPILPGIF
PIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVAMCQELLASGVVPG
LHFYTLNREVATVEVLKRLGMWNEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYR
TQAWDEFPNGRWGNSSSPAFGELKDYYLFCLTSKCPREELLKMWGEELTSEESVFKVFAY
YLSGEPNQSGHRVTCLPWNDEPLAAETSLMKEELQKVNQRGILTINSQPNINGKPSTDPI
VGWGPSGGYVFQKAYLEFFTSSETVAALLQVLKKYELRVNYHIVNVKGENITNAPDLQPN
AVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYH
LVNLVDNEFPLDNCLWQVLEDTFELLSKPAPQ
>A0A2S9PWR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ST5x|TrEMBL
MALGTASTRPDRARTVRDILATGKPSYSFEFYAPRTEKGERSLWNALRRVEAVAPSFVSV
TYGAGGTTRSGTVKATQDIAADTTLTPVAHLTAVDQSVAELRNVLGQYADAGIRNMLALR
GDPPGDPLGDWVPHPDGVHYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDVRHFAA
KCRAGADYAITQMFFDPETYLRLRDSAEKAGCDTPIIPEVMPVTSARQLDRLPSLSTARF
PEDVKQRILSAKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHRQP
>A0A1G2YC56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RBG_13_44_8b|TrEMBL
MKVTSLFKQGKFVVTCEVGPPKGIEVDKVLDEFMPLRGRMDAFNVTDLQSAVMKVGSMAV
CRLLKERGLEPIMQMACRDRNRLALQSDVLSAAVLGIENLLCLSGDHPRLGDHPQAMPVF
DLDSVQLLSVVKTLMSGKDMAGNDLQGKPPQFALGAVVNPGEEPLEPQLIKMEKKVAAGA
EFFQTQPVYEPCKFADFMDKIKHLNVPVMAGIVFLKSPAQAAFMNANIAGIHVPDEIVNE
LASVSKEQRVEKNMEISARLIKQLRDLCQGIHIMSLGWERHITTVLEMAGL
>E1ARJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora aureofaciens|TrEMBL
MTALREALAGGVPSFSFEFFPPRTDAGSRVLWEAIRRIEALAPTFVSVTYGAGGSSRDRT
VEVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADVGVRDVLALRGDPPGDPNAPWV
RHPQGLTHAHELVSLVRDSGAFSVGVAAFPERHPRSPDWESEMRHFVAKCRAGADYAITQ
MFFHVDDYLRLRDRVAAAGCDTPIVPEIMPATDVRQIGRFAELSGASFPGELARRLDAVR
DDPAAGHAIGVEYATAMAQRLLAEGAPGLHYITLNRSTATLEIHRNVLNSRSTQHVLAAH
R
>A0A1F5LW72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium arizonense|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKALGLRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVKYIRKTHGDYFCVGVAAYPEGHPADAFQDIQDPARDIPY
LVEKTVAGADFIMTQLTYDIDAYTKFEDMLRNHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPISRRMEELKHDDDAVKRAGVDIVSEIVGGIKDLPCPGPRGFHFYTLNLEK
TVSFILEQSDLIPPYSEMDDSAIEEGAPLDFPGRALGRSRASSMHSQPHNRVIVDKLSVH
ESSQDSVHEALADSVGMPMQPNRSTTLQISEGLGSLGREATWDDFPNGRWGDARSPAFGE
IDGYGPSLHVTSAAARRLWGHPVDSSDMSTLFRRHVSGELHMVPWSEGGAEEGSGGLNAE
TELIRPELLKLIDGRGWWTLASQPAVNGVKSDHHIFGWGPQREGFVFQKPFVEFFCSSND
YINILKPLFAQHGHNKLTWFATNITGAFESSLPAQPADVELDDLGSNPESVNAVTWGVFR
GKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTETYLDTTKNDAWLVCVVGQQF
GAGTKRGSKEEEDEVKWMWRVLAGEDA
>A0A6B3CV53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID6648|TrEMBL
ETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPTADWVAH
PEGLTYAAELVRLIKESGDFCVGV
>A0A6L7WW06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSAEASDVSVATSPPYSHLQAVLAAGEFAVTCELGPPRAPDAADVRKKVGIIRGFVDAA
SCTDNQGAALKMANWGAALLCAQGGVEPIMQLSCRDRNRLAIQSDVIAAQAFGVRNFMSI
SGDSLVLGDHPMAKPVFDLQGVQLVRLLRRLRDEGRTAAGDPIKGDFGYFIGGAANPFAP
PYGWRPLRMIKKTEAGQEFALTQMIFNVERFADWMSYVRDEGLDERVHIFAGVGPLKSAR
MAEFMKFKIAGMEVPDEVVERMRAAKKPRTEGVKICLEIIEQVREIPGVHGVHIMAIDWE
RAVPRIVKAAGLKLPRPVPEPSLAPGVLEPVSAA
>A0A7C3JXJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGKALKGSPQYCIGAVANPGAPDLDKEIARMGEKVEEGAEFFQTQAVYDPDAFAKFMERA
KAFAKPVLAGFIVLKSGDMARRLNATLPGVSVPDAVIAELDAAEDKAAKSVEIAGRVIAA
VKPLCQGVHIMAIGWESRIPAILQAAGVPKRP
>A0A178Y8Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium saheli|TrEMBL
MAMSHSIDLADQNDVLRSFTLEVTARDVHDLAVLSGGIPKGTIISVPFLSKESDHDRVAA
ARTVRRAGYEPMPHIAARRLSSENALSAMLSALVSEAQVSRLLIIAGDADPPKGPFRDTA
TILRSGILQHHQIRHVSIAGHPEGHPVQGAPVLRGALLEKCQILEEAEIEWSIFTQFAFA
SEPVLGWIDELRRLDINCPIHVGIPGPANVKTLLKFATLCGVSASTAVLKKYGLSITQLL
STAGPDALVREYIDALQGGAYGDVRLHFYPFGGLNKTITWIRNFRS
>A0A7C3LLT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLEVLPPLDWEKVGKDTWRDVLRQVKKVGAGKIVRGLLSASAEVRKSTWDGIFRPVRQPD
WWNGDSKYHAPAYAEPASELERRLAAGEFVITSEIAPPLSSSTDKLIQSIEKIKPYVTAL
NFTDNASANPRMTSWACSTVALDYEAEPVLQISARNRSRSNLQSEVIGATALGVRNILCV
TGDSAKLSPTPREKMDINDLDAIQMLWILRRMRDEGKYLDGREMKIPPKFFLGAAASPFA
SEPRFQALREQKKVNAGAQFFQTNLVYDINGMETWLEDLAKRNVLDKVYILIGIAPIKSL
NMAAMLAKVPGVYMPHRIIQRMEYAHTAGNAQEEGMQIALELISQIKRYHGQGIHGIHLM
PVGWDDVVPRIIREADLLPKSFLIPAVPTQNLAKV
>A0A1F5YEA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Glassbacteria bacterium GWA2_58_10|TrEMBL
MENRFREKLTRSTDFVISVELVPTRGLMRKDFEELISFTEAAVEYGKIDALSLTDNPGGN
PRLAPDVLGLDILYRGMSPLVHLTCKDLNRNGLESRAFQLNRMGVENVLALTGDYPVDGY
QGVARPSFDVDSVGLLNMLREMNRGLKVPLLKPGKFQELEPTNFFIGASVSPFKKQRSEL
LGQYLKLEKKAANGAAFIITQLGYDMRKFDELLRYMSVNNLQLPVLGNVYVLNRFVSKIM
NQNQVPGCVVTDELLEFVNRHAASDDKGKSAFLEFAAKQVAVLRGLGFRGAHIGGYALSF
EDKRQIIDTAETIAGDWRSFIKDLLYPQKDEFYYFRGDPATGLSADQPGKSGENKRPGPR
VTFELMKFIHEQFFEPGTNGFRIARGVCRCIDKSPEATKVFQKFETGVKWLTNNCQGCGD
CSLAELTFLCPEDGCPKGMRNGPCGGSFDGICERKDRKCYWTRVVKRMDKEGGLDKLKEA
KPIIPNAALKDTSSWLNYYLGRDHAALGTNDPVEEKKGKK
>A0A6L9J2K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MECVLRAGHFAATGELGPPQSADATVIREKAGLLKGFCDAVNITDNQTAIVRMSSIGAGS
LVVQEGLEPIIQMTCRDRNRLAIQSDLLGAYALGMRNLLCLSGDHQQFGNHPTAKNVFDM
DAVQLIQMVAQMRDEHVFQCGDGFKGQEPRFFIGAAAAPFADPIDFRPYRLAKKINAGAD
FIQTQLIYDIEAFKVYMDKVRKLGLHERAYILAGVGPLKSPGMARYMKNNVPGLLVPDAL
IERMTAAGAPWADKSKDELTKEDKRARSAAWKAEGIQICVELIQHLREIEGVAGVHIMAI
EWEEAVKPIAEGAGLLPRPTVTAQQPGRGDGGGDHG
>A0A7K0ICR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonibacter urolithinfaciens|TrEMBL
MRSVSDIYAAARAAGRQPVSFEIFPPKGDLTLETAHEVAAELADLLPDFVSVTYSAGGSG
NRQATADVAAMIHDDFDIPTVAHLTCLGATEESISRAIDDLKRKGIASVLALRGDRTADA
SAAEGPFRFAKDLVMRLADEGFCVGAAAYPEGHIECTDFRASVAHLKQKQDAGACFFVTQ
LFFDNAYFYRFREAADAAGISVPIACGVMPFLGKAQIQRMVFMCGASLPSPIIKLLAKYE
DDAVALRAAGIEYACAQLVDLQEHGADGLHVYTMNQPDIARACAGALRATWRPAGEVAVR
GAG
>A0A7V4ICT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MHLIRDIYAAQADKRPVISFEFFPTKTDDGERNLMEKTIPALGRLRPDYCSVTYGAGGST
REKTLHTVARIQNEHRLPTMAHLTCVNATVAQTRAILEQARALGVRNILALRGDPPGGSG
EFQATPGGFTYSYELVQLLRELGGFSVGVAGFPEGHVACREGKEVDWQRLIHKIQCGADF
VITQLFFDNADYYAFRDYLTRRGVRVPLVPGIIPIGSAAQIQKFTALCGARLPAPLRAEL
EKLADDDAACAEFGIRYATRQCADLLAHGAPGLHFYTLNKAAATSAILRNLGLA
>A0A3M1NGX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
EQAFEAFYEQIAALILGGVDLLILETFTDLNEIAEAVRAARAANPRVPVVASMTLTRDST
TIYGDSPREIANALAATGANVIGVNCSSGPSQLARVAQIMRQAQPEALLSVMPNGGFPEL
VNGRVMYPAAPDYFGDYAVILRDIGVTIIGGCCGTTPEHIRAMRTALDTPERKPRIVVTS
NEPSPLHTSGIPEAPTRLAQKLALGKFVTTVEMAPPRSFNAQKILASAQMLQEAGVDCID
VSDSPMARMRMSPWAVCHLIQDRLGMETILHFPTRGRNILRVQGDLLAAHALNVRNILVI
MGDPTAIGDYPEANDKYDIVPSGLIKLIKQNLNGGQDQAGNSIGQPTAFTVACALNLTPK
DLDAEIQSLRKKIEAGADFAMTQSVYEPHKVELFLKRYEALYGKLTLPILVGILPLYGAR
HAAFLNNEVPGISIPESIMARINAAGDVAPAVGVQIAAEILRDLRGMVQGAYIIPPFGKY
EMAAEIVESLAQPV
>E1RA39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sediminispirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228)|TrEMBL
MLKPYLERLADGVLLFDGAVGTMLYEKGVFLNQCFEHVTLTSPEKVSELHREMIAAGAQA
VTTNTFGANRLRLDGYGLSELTGKINREAVRLAREAAGKEVYVAGSVGPLGKRVGPVGKI
DSEEARSVFREQMEALAEAGIDLFVLETFRNIDELLLAAETAKATAPEIPVQAQYSFRPL
RSEQYNNDLTPVFARLQESEHVDVLGINCSTGPAHMLDVILASGGVVSKPISVMPNAGYP
RDYEGRQLYMASPDYFAEYALKFLDAGVHVIGGCCGTTPLHIQKMAQAILHLDSSRHKGL
SIEVSSKEIERLEPVALEKRSAFGAALAKGEWITTVELVPPMGIDLSKAIAKAKTLGDAG
ITCVNVPDGPRASSRISTLVTCMEIQRNSGVETIQHICCRDKNLIGIQSELLGAQTAGVH
NLLLLTGDPPKVGNFPDATGVFDTDSIGLLSLADSLNQGIDLAGNRLHGQTSFVAGAGAN
PAAQVLEREVERAWKKAEAGAEYFITQPVFDVELLSTFLDKIKGTGKPVIAGIWPLASYR
NALFLHYEVPGISIPADLQERMKKHDTKEGAMEEGILIAREIIAKIRGRVAGVQVSPPFG
RLEAALQVIKNQEDI
>A0A0F4P6V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas piscicida|TrEMBL
MALTLQEKIIDPNQGVYLIGTTPPKIGTDPEQLKSIAAKLLGRLHEIEYDGVIIYDIQDE
SSRTQVPRPFPFKHTVDPCEYSQLIRELSHLDVITYKSVAQRDSEAFGNWLSSTKQQYGL
NNLVLVGSPSSQGDIKLPLSEAYKVLKHHQDDFFLGGVTIAERHASKRNEHERLIDKTEQ
GCQFFVSQAVYDAQATIDLITSYARTCKQQGQTPKRIILTFTPCGGEKTLQFMEWLGISV
PEATKWRMLDAENTLSESIRICRENLDQILKSCSHLDISLGLNIESLTNRKEEIDASINL
YRLLKATMELCLAEKQIA
>A0A7K3HSE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFNTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A6F8V6E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimicrobium lacus|TrEMBL
MNSKPILSFEFFPPKTPEGMDKLRATRQQLAQLNPEFFSVTFGAGGSTRDRTLETVVEIQ
QEGRKAAPHLSCIGSTRENIRAILDEYKGHGIRHIVALRGDLPSGTQDVGEFRYANELVA
FIRAETGDYFQIEVAAYPEFHPQAPTAQADLANFKRKVDAGANAAITQYFYNADAYFNFR
DECDAMGIAIPIVPGIMPISNFSQLARFSDACGAEIPRWLRLKMQGYGDDTASIRAFGLD
VVTAMCDRLLQGGAPGLHFYTLNQAGLITTIWQRLGL
>A0A6L3F0E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSTLSNLGKKLDEKFPRLLTSLGRVLSPVEAVVKKPVFGCHMCGQCVLHSTGMTCPMECP
KNLRNGPCGGVGMDGSCEVDRSMTCVWFNAVNRSDKFPWPQEIYQRNPAVDWSLQGSSSW
INAITGRDHHARTGPQWQQVEFFGVNEKPMYTGSRLERLMRAGEFVVTCEVNPRDTADGT
ELIEYAKTLEGIIDAVHVSDNFLAQPHMSGTVAACMIEQMTNLETVLHLTCRDRNRLQLQ
ADLLGAHAMGVRNVLCLTGDHPKLGDHKEAKPVFDLDSITFIDLVRKMRDEGTFDSGREI
IIPPKFLIGGAIAITAPPLEFRPHRMAKKMAAGVNFFTSQLVFDMSLLESFMKRVHELGI
IQNTHLLIGVGALPGPGTAKAINKHTPGVVIPESIIKRLEGVSKKDRRKEGVKIVAEQIQ
QLKEMPGIAGVDLMDMVPDSWFPTPEIVELAGLEDRPEPHATAHQSDPNQ
>A0A399Z0B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPKLPFLERLDSGIPVVADGAMATQLHRSGLPMATCFEAVNLADPDKIYAVHSAYLAAGA
ELLETNTFGANRQKLSEHGLSDKLAEINGAAVEIARRAIADSGRDAYIAGSMGPLGQKIR
PYGPISREDARGMFFEQAAALIAAGVDVILLETFADHHELLEALAAVRLVSPDVPVVTHA
TFASDDRTLTGFTPAKVAADLVRAGADVIGVNCAGGPAQISHILETMHTCVPRARLSAMP
NAGFPESVNGRVMYPASAEYFGDYALTFQALGARIVGGCCGSTPDHIAAMRRAIDAAAGG
ERSLPIIHVEEAAVSEDQIAPAAPTDFAERLASGQFTVTVEMAPPRSFSVERLIRSAHLL
RDAGAHILDVADTPAARMRMSPYAVAHVIQSQVGVETVLHFPTRGRNLLRIQGDLLAAHA
LGLRNVFVTMGDPTRIGDYPDANDSYDIVPSKLIGLIKHSMNRGVDQAGNSIGAPASFTV
GCALNMGADNLDHEIKILGAKLAAGADFALGQPVYEPWRIERFLTRYEQVTGRVFDLPVL
LGVLPLFSLRHAQFLHNEIPGIVIPETILSRMEQAGDDAPYEGVRVAQELLQATASYVRG
AYIIPAFGRYDLAAEVVAATPVRA
>A0A6N8YRF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MDFSLSERLSRGLLLCDGATGTQLYAHGLSAALLEPANVEQPDIVKGVHLSYLRAGAELI
ETNTFGANAAKLGMHGMAHRVEELNRAGVALAKEAARLHGQNVWVAGSMGPLPPDSTGAG
LFSPASVRNVLAEQASALSDAGADLILLETFTSLAQLRLAIDAVRSVSELPVIAQMTFTG
DGLTSSGDAPEDVIAALNEADLLAFGANCSIGPDLLLSVVERMAGSAGMPLIVQPNAGLP
AYVGGRLEYTAPPEYFAETAREIARAGAAAVGGCCGTTPEHIAAVRDAVRGVLQSSTRRA
PAPAVARPQHVEAPATRPTGLAERIERGEFVVTVELSPPRGFDVSGTLDKLRGVVGSVSA
VNVADSPRAQGRMSALATGSLVQSRLGVEAVMHMAIRHRNLLALHSDLLGAHALGLRNVF
TVMGDVPLTGDYPYATAVSDVTASGLIQLMAGFNEGVDANGREIGQPTSFFIGAALNFNA
PDLDRELRVLERKVKAGAHFLLTQPVYAAEHVERVWSLLGGFPLPVIMGVLPLRNARHAR
FLQNEVPGIVVPEDVMRRIDLAEYRGDAGGKEGIALSRELLTALSGRIAGAYFMPPFERF
GVVQETMEGLSMQGLSSQ
>A0A6L3EWH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPGFTPGRRWQPAYTPFKRESFGNRALAKLELLVKGPMFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGATEQCYVDESRPCIWHAIYERAFRMGREDLLMEVLPPLDWEQVGTETWG
DVARQVKKVGVKTAVSNLLSRDKKQREFIWDAIFRPVRQPDWWQGDSDYHAPAYTEPASE
LERRLRAGEFVVAAEIAPPMSTATGKLKREIKMLKPFVTSINFTDGASATPRMSSQACSL
MALELGAEPVMQIAARDATRTSLQSQVLGTSAMGIRNVLVVSGDSARIGVTPQSRTDILD
VDSVQMLWILRKMRDEGRYLDGRKIKFTPAMFLGAAASPFASSPRIQAIREHKKVNAGAQ
FFQTNLVYDVEGLERWLEELAKRDILDKVYILAGLTPLKSWNMTRYLHENVPGVRLPETI
LKRMQTAKDAAEEGVAITLELIEGIRKLQGINGIHLMPVGWESIIPRLVKEAGLSDAVKA
AP
>A0A7K2G605|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4950|TrEMBL
MALGIPSTRPDRAATIRDLLASGHRSYSFEFMPPRSAEAEVGLWTAIRRLEALSPTFVSV
TYGAGGSTRGRTVNVTGRIAQETTLTPVAHLTAVDHSVSELRNILGHYADQGVRNILALR
GDPPGDVLGPWTRHPEGIEYAAELVRLIKESGDFCVGVAAFPEMHPRSAGWDDEIRHFVD
KCRAGADYAITQMFFDVDTYLRFRDRVAAAGCATPIIPEIMPVTTIRSLRRVPGLSTAAF
PPALAERMLAARDDPKTVRALGIEHATAMCRRLIDEEAPGLHFMTMNFSKVTTEIYRTLG
LHPA
>A0A366GTL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. DB-2|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRATLNVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A536Q156|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARISELLAAGRTVSFEFFPPKDNEEQALLTRTIADLQPLKPSFVSVTYRGGRISRERTT
RVVTDLLRTTDLTPMPHLTCVAHPRFELGEIIGGFRAAGLENLLALGGDPLPAEESYKEL
EYAWQLVELGRRLGFESIGVAAHPAGHPRSPDLRSDREHLAFKMRLADFAITQFFFKVEE
YERLRDEMAALGITKPIIAGIMPITSLVSVQRMAELSGYAVPVDIVQRIEAGGDDRAEIR
KRGIDVATELCRDLLEAGVPGLHFYTLNFSKATREIHARLGFVTHR
>A0A1G0XFN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium RIFOXYD12_FULL_36_8|TrEMBL
MKVIEHLAKAKDPLISFEIIPPKRGGDIHGILSVLDDIMKYRPPFIDITSHSAEVVYEET
PTGIKKKVKRKRPGTLGICALIQNKYDIDAVPHILTKGFTREETEDFLIELNYLGIKNVL
AVRGDDSAYEKPIPEGRSANKTAKDLVIQIMDMNRGKYIEDSLLDAKPSNFCIGVGGYPE
KHFEAPNLKSDIKFCKEKLEAGADYVVTQMFFDNSVYFNYVEQCRKEGITAPIIPGLKII
SAKSHLVNIPKNFHVSLPDELVDEVNSAKPEHVLDIGVAWAAKQVEELLSKNVPSVHFYI
MQNSAPVKKLMNRLKIFKKIA
>A0A2E2V4I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSRFCITKSSLRKSPKLTKIVDSAFEKTGLPCFICDYSPPRSGVLNRENHPNIEAHFLSI
AHSPGQSVRASSSMVASKVKSLINQDVVFTIATRDKNHMALQSELLGAQLLGLENVIVVR
GDPAKHENSTVVNRTGPLPTTQVISGISNMNRGRDYKGIALDVPSDFCIGATIDLGRRFS
SECNLVLRKIESGAHFFITQPVFDVTKALKLLENIENQIITRNHTPIFFGLQILEPDSIS
FSKVPTTLLDQLQKGKSHLELAVELYETFREAGINNVYLVPPIKKGGTRNYQAAIEVLAK
LKPA
>A0A2E9TDK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MISSTRRLPLVSFEFFPPRTSHAARTLWRSFKRLEPYGPRFTSVTYGAGGSTRERTHQIV
QRMQEETDVPAAAHLTCVGATRDEVDQVARDYWEAGIRHIVALRGDAPAGSDGYHPHPDG
YHYASDLIAGLKRVVDFEISVAAYPETHPEASNADADLDNLKRKIDAGATRAITQFFFEP
DLYLRFMDRARAAGITAPIVPGILPVVDIISVSRFAERCGASVPDWLVSRFGRVGSGTQA
RSSIAVSVATEFTHRLMLEGVDEFHFYTLNRAAVVARTCENLGIVPAEAPVVTG
>A0A2E2DTI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MDPQSGGKTVAKVTDRCFEATGHSAFICDFSPPRTGDPESFTQPNLDADFISVAYNPGKA
VRVNSAMLAAAIKGETGKDVLFTLATRDMNKLALESLLLGGQMLGLENVVVVQGDPFTQR
DLTRVKDVSDFTPTRMISAIAAMNLGTDYREGQLRSPTRYCIGATLDLGRGIGSEAQLAH
RKAQAGAQFFISQPIFDVADASRFRQAFEESAGHDSELPVFFGLQVLEQDGIIFSSVPET
VRQELEQGRPGVEIALELFHRFQQAGLHNIYLVPPIRRGGARGYGAAREVLAGVERL
>A0A535DNV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNQDSYDLSPGAAAPAPIAATAREGVSQPARAAKEPRTFREKVEAGRFVMTVEVDPPHGL
NARRAIEGARLLKDAAVDAINVGDSPTAKVRMSPLAMSVLLKQQVDVEIVMHYTTRDRNA
MAIHSDMVGAHILGIRNILCLRGDPPSLGGYTDIVGVWDVSAVGLMRFLKLLNDGVDFTG
KSIGRQASFFIGGSANLNADPLEPEMRLMRRKVEAGAHFFFTQNVFDERVLERFCEGAKK
FGRPVIVGVLPLANQR
>A0A1U6IZ03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. P2b|TrEMBL
MIGTELTGAASERVTRSGTKPHTRASREVRSLPTRLEIIPTEGITAGVRAHVPAGSTITV
TCLPHHGIARTMQTALQLAGMGYSVVPHLAARSIGSRGQLEAALRDCRDAGIREVFAIGG
DASEAAGPYSNSLQLLEDIMELSGGDISAGVAGYPEGHPHHGELQMLDALLEKQHLASGV
TTQMCFSVPRISWYAETLRREGVQLPIWAGVPGAVPRAKLIALAAKIGVGPSLKFLTRQG
PLGRRLLSGGSYSPLPILDQLRDVTEIAGIHLYTFNSLGHGNPQATS
>A0A1G5HXT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga guangxiensis|TrEMBL
MSPLTLRPSRQTSCPIKVSFEFFPPKTPEMETTLWASIQRLAPLNPQFVSVTYGAGGSTR
ERTHATVSRLVQETSLKPAAHLTCVAATKDEVDDVIRSYWDAGVRHVVALRGDPVSGIGT
AYEAHPGGYRQTCDLVAGIKAIGDFEVSVSAYPEKHPEAASLEADIDVLKAKVDCGADRA
ITQFFFDNDHYFRYLDRVRARGIDIPIVPGIVPVQNFKQTANFAAKTGASVPDWLAARFD
GLDHDVETRKLVAAAVAAEQVIDLVDRGVSEFHFYTMNRADLVYAICHLLGLREQTVKAA
A
>A0A3M0YV02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MHSTLQRRLTAGQTVVTGEIAPPKGAARAHLETLAQNLRTYVDAVNLTDNQRGIARMSSL
GGSVILHQLGIEPIMQMTCQHRNRIALQADALSASALGVRNLLAMTGDHPRIGDHPEAKN
VLDLNSFQLIRMLRTLRDQGTFQSGTPLKEAPRFFIGSVANPNVERAARLEKKIE
>A0A535WU62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVRPLGGLSVGQALAEFLRTPRYEIFPTDDVLDLVAAYVPKEVTLAVTASPRRGLPATVQ
LAARLSQLGYRAVPHLSARLIRDRAELGQILEALKAASIQNVFVIAGDAREPAGQFPDSM
SLLEALPPDHSLTEIGVTGYPESHPFIHDDVTIQAMWDKRRIASYIVSNLSFDPATVKRW
VERVRRRGVQLPIHIGMAGVADPARLLRLSAKIGVAESARFLRGHPSWLARMFRPGGYDP
GRFLGALMPEIAQPGRRIAGLHVFTFNEIEPTERWRREMLARLTPVARRATAE
>A0A1H3ZZX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium KH3R12|TrEMBL
MRVSELINNTGKTAFSFELLPPLKGNSIQQVYNAIDRLKEFDPKYINITTHHSESIYKED
ENGTYRKVNVRRRPGSVAIAAAIQNKYGIRAVPHIISQGFSREETEYALIDLSFLGVTDL
LLLRGDTKKLDAEQRKMDCHQHATGLQEQVNNFNEGITFDGSSFTPPEEPFSYGMACYPE
KHEESPNMESEIYYTKMKVDNGAEYLVTQMFFDNSKYFDFVKRCREVGINVPIVPGIKPI
HLKNQLTALPRIFRSDIPEELAVALRKCKDDDEAKEVGVEWCITQCKELIRNQVPSIHFY
SLMATESVRRVAKEIY
>A0A536AAR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSALASLLRSGEFVVTAELNPPKSAAAAVVRRRAEALKGVVDAVNVTDSNRANVAMAAIP
AATIVRSVGLEPIVQMTGRDRNRIALQADVLGATAIGIENFVFMSGDDPKQGNHPDAVYV
KDLDGVGLVKMAVAMRDQGQFLSGDEIKQPPKLLVGATASPFTKPMEADLAKTFEKIAAG
VEFLQTQPVFDLVTFSRWLVEVRRGASRDVPIIAGVLVLRSPDQAERLAKVPGLAIGPAV
IERMKKAADTEAEGIAVAVEMVKAMKALPGVRGVHLYSIEWPEAVGRVVESAGLLPRPDA
RVPA
>A0A661W9F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSRSNSSRRIPVPDETKSPCSRLEEILRAGHFAVTAELNPPDSADPEDVYRAAGVLAEVC
DGINAVDASGANCHISSVAMCALLTRAGYEPVYQVTCRDRNRIAIQGDMLGAAAMGVLNV
LCLTGDDVTAGDQPEAKRVFDFDSIQLLRTARTMRDEAVFLSGRKITSPPCFFLGAAANP
FVPPYDWRPQRLAKKIAAGAQFIQTQYCFDLDRLKEYMKQVRDLGLDKQAFILAGVGPLK
SAGAAEFLRSKVPGVVIPDNIVDRLKKT
>A0A535N7L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRAALQPVAGAPRIRQAPASTAIAIDLNPAEQLPATPFAQRLVDRSFVVSVEIDPPRGLN
PSKCIAGAQLTKDAGADAINIGDSPMARVRMSALSLAIMIRQQVGIDTLIHFTSRDKNLM
>A0A2D6F426|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKITEGCFEATGHTSIICDFSPPRSGDPVAVEQAQIDADFISVAYNPGRAVRTNSAMLAA
AIQRSGKDAVFTLATRDMNKLALQSELLGAQMLGLRNVVVVQGDPFGQQDQARVASVNDY
HPTGLIAAIAQMNQGVDFKEGQLRSPIDFCIGATIDLSRGIEEEAQLAVRKVQAGAEYLI
TQPVFNVDHVAQYWESYAYHSGKAGIPPIYFGLQILEKDCVLFSSVPESVRGELEEGRSG
ADIALELYQKFQEARLNNIYLVPPIKPGGARNYEAAKAFLGKINKR
>A0A359HQU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MFVVMGDPTAIGDYPEAMDNYDLAPSGLMQLIAQRFNQGVDHAGSDIGQPTRFFVGCALN
LLPPDPEREIKLLRRKIANGANFALTQPVYQPEKAREFLDLYAKQFGDLEMPVLVGILPL
YSVRHAAFLHNEVPGIVIPEEIRARIAEAGEGAPQEGVRIAVELVQQIKTWGQGIYLMPA
FGRYDLAAEIVEAIR
>A0A535N9U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRSAPSRLAALLRQGHFVVTAELSAIDSPDPAVTLNRAAALRGHADAVNCTDNTGAHVHL
SPLAAAHLVSEAGVEPIMQLTTRDRNRLGLQADLLGAAALGVRNVLIMSGDDVSAGDHPE
ARSSYDIDSMQLVRIARTMRDQGTYLSGRRMESAPSFFIGAVENPFAPPYDFRPARLAKK
VEAGAEFIQTQLVFDVPRLDAFMRRAGDLGLLERVAIIPSVAVPRSARGARFMKEKVPGV
QIPDAVLRRLEAVPVARQAAEGIRIAVEIVNQLRDIAGVRGVHVIAIRWDEGVLTVIEEA
GLLPRPLAGAGAAVAALP
>A0A536CCP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MWRGRFYLSNLASLLRQGEFVVTAELNPPKSASGEVVKRRAGLLKGSVDAVNVTDSNRSI
AAMAAIPAALLVREAGVEPIVQVTGRDRNRIALQADLLGAAALGLSNFLFMSGDDPKHGN
HPDAVYVKDLDGVGLVKMAVTMRDEHKFLSGDEIRQAPEYFIGATASPFTKPMSADLERT
VQKVGSGADFLQTQPVFDLATFSQWLAELRRVGGGREAAVIAGVLILRSAEQAERFARVP
GVALGQEIVDRLKKAADAEQEGIAIAVEMVKSLRALPGVRGVHLYAIEWPEAVPLVAERA
GLLPRPKVKESNP
>A0A535D7D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIAERLKRREPVFSFEFFPPKTPEAVERLYDTARRLKALQPTFVSVTYGAGGSTRQMTV
DLVTRMKRELGLETMAHLTCVGHTKEELAEVLDELAAGGIENVLSLRGDPPKGQTHFVRP
VGGFGYAQELTRFIKGRYAFCVAGAAYPETHTEAPDPDTDLRHLKEKVESGAEFLITQLF
FEPDLYFRFVERARATGIDVPIIPGIMPVTNVAQIHRFTSMCGATIPSSLRDLLDRAKDD
EAAVIAVGVEWGRDQARRLLEGGAPGIHFYTL
>Q251W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfitobacterium hafniense (strain Y51)|TrEMBL
MTCLDWIYLCEEGGNTESRRLNPIDKVEKTFREGKGIEMENRFKQSLLDPNTLSVTWELV
PGRGAREKAQESALLAAEQAAKGGKVHALTITDNPGGNPAILADYLGQEILKLGIEPLVH
FTCKDKNRNQMESQLYALDRAEVRSLLVMTGDYTVSGFKGRPKPVFDLDPTHTLELIAQM
NEGLGIPGPKGMSYHQPSDFFAGAAVSPFKGTEAEQMVQYYKLKKKVTSGAQFIVTQLGY
DARKIHEVLQFMKLNDLNVPLVGNIYILPFGAAKIMNQNQLPGCVVTDKLLAEIDKERTA
EDKGVSARLLRAAKMYALMKGMGFAGVHIGGHNIKYEQVEYVIEKGEELSKDWLALVPEF
DYPMPNGFYYYEKDPKTGLNTTTPVNRKNLPLDAPVGVAYSGMRLMHSMLFTPGKNFFPV
MRKIYKGRKDNRKHGLEHLAKVITNDCKDCGDCAMFELAYLCPMSQCPKNQRNGACGGSY
QGWCEVYPNQKQCIYVRAYARLKKYDEEGDLDSHHIPPANWDLYQTSSWSNFFLGRDHSG
KILGIPTPEEEAKAKGADPAK
>A0A6N2V7C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides intestinalis|TrEMBL
MYKRIAQQIKAYLISFSYFCSQCTNKFCSPNKDNEKEMRIIDLIHSNEKTAFSFEILPPL
KGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDLGNGLFQRNRLRRRPGTVAVAAAI
QNRYNITVVPHLLCSGFTREETEYVLLDLQFLGITDLLVLRGDKAKHESVFTPEGDGYHH
ATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYPEKHEEAPNIDTDIYWLKKKMEAG
AEYAVTQLFYDNQKYFDFVERARKSGVTIPIIPGIKPFKKISQISMIPKTFKVDLPEELT
CEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHFYSIGAVDSIKEVAKLVY
>A0A4D6LDY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vigna unguiculata|TrEMBL
MKIIEKIRAAAADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANRMQNIVCVETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLLG
>A0A8D9RT63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosococcus oceani AFC27|TrEMBL
MQPQQNNPLIFSCEFFPPKGEENASKLRRVRRKLARIHPRYYSVTFGAGGSTRDRTFETI
LEIQAAAKETGIEAAPHLSCVGSSRKSIREVLQAYQHQGVKRLVTLRGDLPSGMVDPGDF
HYASQLVEFIRAETGDYFHIEVAAYPEVHPQARSAQADLINFKHKVEAGADSAITQYFYN
VDAYLRFVERCKSVGIDLPIVPGIMPINNYVQLARFSDACGAEIPRWLRKRLEDFPDPAT
MSAFAIDVVSDLCYRLLEAGAPGLHFYTLNRADPTLAIWDNLGLETQPANLSAVTKI
>A0A830ZW54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia amylovora NBRC 12687 = CFBP 1232|TrEMBL
MSFFHANQREALNQSLAEISGQINVSFEFFPPRTGEMEDILWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELRSIAEDYWHNGIRHIVALRGD
LPPGGGQPEMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRVPGWMTSMFA
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPGLALAA
S
>A0A4R7HUV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ilumatobacter fluminis|TrEMBL
MVHGPCGGVTPDLGCEVDGRPCPFVDAVVTEAAVEVIHRARPVDLGRFVIDLRLPTDDAV
LAEVAAIYRDVGAIVLVGEHVDDPDDAAPHHHADRLAEMGLPCVVTVTGRRRSPDQHRAE
IERLVAAGVRAVHCITGDHPAARFGPDATATFTLDGAQLAGIARSAGAHVSVAESPIAPP
GDRRAERVAMKERAGADVVILNHAGAPQAVAEFADGCGAAGASLAVVAPVPVMTDVSSAR
ALSQFPGVALPDGLADRILASDDPVETGVAAAVELGDELLSDDRFAAINLSGSATAAGPV
ERARLMASVAERLR
>A0A1F9QQZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium GWA2_56_46|TrEMBL
MKITERLKRPGKLFSFEFYPPKTEADSEKLFETVKELKALDPDFISITNSSTGAAPYRTV
ALSGVIKEKLGLEVMAHLTCIGHSREEIKAIAGRLKILGIENVLALRGDIHNIEGIPPKR
EYRYASELAADLKALGGFSIGGAGYPEKHPEAADFETDIKALKTKTEAGADFIITQLFFE
NRFYFEFVEKARKAGVAAPIIPGLMPLTSYKQLQNFSKLFSVFLPRVIKDGVEKYADDKE
SLLKFSVEYASRQAEELLKRGAPGIHFYTLNRSKATKEILKNIR
>A0A519GFD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax sp|TrEMBL
MSTLTPSSALPLSLEFFPPKTPEGVDKLAAVRQQLYPLKPQYCSVTYGAGGSTQDGTIQT
VRAILSEGFDAAPHFSCIGASKASVREQLAQFAKQGIRRLVALRGDLPSGYGGFGEFRYA
SELVAFIREETGDHFHIEVAAYPEVHPQARSPQADLQAFAAKVKAGANVALTQYFFNADA
YFRFVDDVRQQGLDVPIIPGIMPITNSTQLMRFSDACGAEIPRWIRARLESYGDDKASIQ
AFGLDVVTQLCERLRGGGVPGLHFYTMNQSAPVLALCQRLGW
>E7S9L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus australis ATCC 700641|TrEMBL
MTKQTPSLSFEVFPPNPEVGNAKLLRALENMQELAPHFISVTASNNKYNIKETTVALANH
IQNELSIPTIAHLPAIYLSKEKVADTLHELDQVGVHRILALRGDIIPGIEPLKDFRYATD
LIEFIKTEAPHFDVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVHHATKALFEHQPKLEVI
>A0A3N5S926|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
PPDGFAYASELVSFIRSISGFSIGVAGYPEKHLEAPSMEIDLENLRRKVDAGADFIITQL
FYNNEDYYRFMDRLTKMGITMPVIPGIMPVTSLSQIDRVTSMCGARVPDELLKRLDACTG
ADSICEAGIEYSIKQCVELKSWGVPGLHFYTLNRAQAVKRIMDATGL
>A0A4Q7UFM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora violae|TrEMBL
MALGLPSTLPNPQPAIGELIREHQPTFSFEFFPPKTPAGEQLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVVGRLAGVGVRNVLAVR
GDPPGNPGGEWIRHPEGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAQFVR
KCRAGAEFAVTQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARV
>A0A085L1N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schleiferia thermophila str. Yellowstone|TrEMBL
MKIIDIIKNTQKTLFTFEILPPLKGDNIFDVYGNIDPLMEFNPPFINVTYHREETVLKPL
PNGLYQKKVIRKRPGTVGLCAAIMHRYKVEAVPHLLCGGFTREETENVLIELDFLGIQNV
LALRGDSQKGQRYFIPEPDGNHYAYQLVEQIQNLNKGIYLDEEIENNTPTNFCIGVAGYP
EKHFEAPNLHIDIQNLKRKVDAGADYIITQLFFDNQKYFDFVDKCRNAGIGVPIIPGLKP
LSTKKQLSLIPHMFHVDIPDELSIEILKAKDNRAVRQIGIEWTIQQSKELIKAGVPVLHY
YSMGKSDNIYQVAKSVF
>A0A1V9UVV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Bc-h|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARTLAGYNPDFFSCTYGAGGSTRDRTINTVLQLE
KEVNIPAAPHLSCVGDSKADLRGLLSQYKDAGITRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLKNFVRKANAGADSAITQYFFNADSYFY
FVERAEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>E3CFV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis F0405|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQPNFEVN
>A0A388K2N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chara braunii|TrEMBL
MTSLYVRTSVSGAFFSSSLSHVPWRKLWDLQLQDDGRRSTAHFLFAGRSACHFISVTKRK
TQDDGLQHSGSRAMATAGNERQTGPPPYEQERSERSYEQERSYSQAQPRGRFIYTVEIPS
DGMPAGFPGGKDGWRAMWASGPFDAVIHPNLPPFQSVREVLQRPHLVTRFFERRRTTNSG
KLPGTGKEEEEEEGKKTKKMLYQHPLRSGVSYSRAVDPERGDNSFQRSPLRYLESTAVPG
SEPGAEPGPGSGPGSEPGLEPGSEPGPGSGPGSEPGLEPGWEPAREDDWGTEEMGPGSEP
CMQIWTVPAQLRSRDEVQADMAARGRQIASHSRGGALLLVSGGHPMRKAPFAEHWLPTNS
FKMLREGHRMRREGILPPQIELWAVENPYVNHPSRFEKKLETGAEAIITQPPLLPDAFGL
WWEAIAQRGLLADTNVIVGVPFVTSYRSFAFWLDLLGASKLPEGRAEADKFRRQLQTLGS
DPDGKALIRSFRRKWILSLMRRVRQLPGVSGMHIMPVTAAGWRDLQTMVKDYPEEFHSSL
F
>V9X410|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FGI182|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2T1EHX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorogloea sp. CCALA 695|TrEMBL
MSNIFRTAVKNNEFLITAEIAPPKGGNPSHMLQIAQTLKGRVHAVNITDGSRAVLRMCPV
IASVLLLQQGIEPICQVACRDRNRIGLQADLMGAHALGVTNILALTGDPVKAGDHVEAKS
VFDLESVRLLQLVGKLNTGFDYNNIALTDGATDLFVGAAVDPQLPSWSSLQRRFERKLEA
GAQFFQSQLITDFERLEKFMSQIAATSNKPILAGIFLLKSAKNAQFINRCVPGVNIPQTT
IDRLANAEDPLQEGIAIAAEQVKLARQTCQGIHMMAVKREDLIAQILDKAEIAPLSS
>A0A4T0WVT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] inconspicua|TrEMBL
MKVTDKLLQAHKDENSSATFSFEFFTPKTSQGVQNLYDRMDRMYNLNPLFIDITWNAGGR
LSNLTSEMVHTTSTVLGLETCMHLTCTNMPLALIDDALQSAYNSGCQNILALRGDPPLDG
SESTGDFKYAKDLIKHIREKYGDYFCIGVAGYPEGHPEESDNRKTLEFLKQKQDAGADFI
VTQLFYDVENFMQWCRDCQEIGITMPIIPGIMPISNYNAFIRRAKWNEVKIPQHFLDRLE
PIKDDDAKVRDEGCVLMTELCQTLIDSKLINHLHFYTMNLEKATMMLLDSLNLITCSSKS
KYETENSKPWRKSLNPSRETENVRPIFWKNRKFSYIQRTNTWDEFPNGRWGDSRSPAFGS
VDMFEHEIIRHSSTKILSLWKKPTNSHELGELIISYLKNEVTCLPWSDTSVTNEIESIKS
SLIELNSNGLLTINSQPKINGVKSNDPVFGWGPSNGYVYQKQYLELLIPRAKLDTLVERI
NAVNKENNYNILNYFAIDSESNNLLSTNIVDPADVNAVTWGCFPGKEVAQPTIVERVSFI
AWKDELYLILKKWSNVLKSASEDLDSQPEEGERVKDIKAANFVQSLIDDYVLVNIVDNDY
VNNEDRIFSLFESI
>A0A6B8VUJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium comes|TrEMBL
MNATASQHSAKRRFSASAPFDSFDPVETHQAQVPSRTSLSFEVMPPRHDADEAKIDELLA
TLRSYNPDYISVTSSRNSGWLEGTARFIEKIDARTRIPTLAHLACTAGTRGELIGWINRL
MDSGVRGFLALRGDYAEGQTGMPAGYLPHATDLISLIRTLENDQRARFGAGRLAIGVAAY
PSGHEESASKDEDIDVLLTKQRLGADFAITQLFFDAEDYLRFAERARLAGVRIPLIPGIM
PMTSLARLRRMGQLSGLNVPARLLSRLEAAGPEGEYQTGLDLTAELARTILAAGAGGMHV
YTFNRPDTTTELLDRIGIAPPPTG
>A8FBU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pumilus (strain SAFR-032)|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYTIEEIKR
SFREQLYILLNEEPDGILLETYYDMEEAKAVLQIARKETTLPIVMNVSMHEQGVLQDGTP
LRDGLSELSSLGADVVGINCRLGPYHMIQALEGVPILENSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHIHAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELATKKRTIIVELDPPKKLNFEKFLVAAKELKNAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMARAGEDKEKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKESNIHVNYH
>A0A7Z6U363|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cannabina pv. alisalensis|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRSLLAQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VNFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLQLPR
>A0A7W5DL50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas fontilapidosi|TrEMBL
MSTQQHPLGISFEFFPPNTDAGREKLVGVRDALARREPRFFSVTYGAGGSTQDRTLNTVR
MVRESGFTTAPHLSCIGSDKGALRERLSRYREEGIDSLVALRGDMPSGTGGGGIGQLRYA
NELVEFIREETGDHFEIAVAAYPESHPQAANLEHDLTNFARKMKAGADIAITQYFFSAEA
YFHFVERARALGVGAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIG
AFGEEVVSRLCQRLLDGGAPGLHFYTLNQATPCLRILDNITG
>A0A7W5GZX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas fontilapidosi|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGKFAITSEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGANCHMSSVSVCSLLTRVGYATILQISCRDRNRIAIQGEILGGAAMGAC
NLLCLTGDGVQAGDHPQAKPVFDLDSMSLLEIARRMRDEQRFDSGRRIEMPPRIFLGAAE
NPFVPPLDWRPHRLAKKVAAGAQFIQTQYCFDIERLREFMLKVNDLGLLEGPDRVFILPG
IGPLASARSARWIRENVPGVHIPDAVISRLEGAENQKEEGKRLCMDLLHEIRDIPGVSGA
HIMAYRQERSVAEIIEATGVLDGRVPWYPGRDDPKALNPESPEAVPL
>A0A7V6LIF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacilli bacterium|TrEMBL
MKTLDLFDSKKVLSFEIFPPRQPGSVNMIYDTVEQLTELDPDFISVTFGAVGQGTRSKTV
EIASKIKNHYGIESVAHLPCINLSKTEALNLIREFEEQGIKNILALRGDINPNIAPKNEF
NYASDLVSFIKEHGDFNIIGACYPEGHIESDSIVKDILYLKRKVDAGTDHLITQLFFDND
YFYSFQEHAAIAGINVPIQAGIMPVVNKRQIERMVSLCGVKLPKKFLAMMQRYEDNPEAM
REAGIAYAVDQIVDLITQGVDGIHLYTMNKPDIAHRIYHAINKLLVI
>A0A852X3E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janibacter alkaliphilus|TrEMBL
MSEQPLRPESGVGTIRRHLSDTRPTVSFEFSPPKDDTGEEALWEALRQLEAVGPDFVSVT
YGAGGSSQDRTLRITEEMARRTSLTAMAHLTCVAQSVDDLREVLAGYAAAGIDHVMALRG
DPPGDPRGEWVAHPGGLDHADQLVSLVRGSGDFEVGVAAFPDVHPDSASLEEDVQTLVRK
ADAGATFAVTQMVFDPETYLRLRDAVSARREMPISAGIMPITSIRQITRMAELMGTPLPE
AVLSRLRAVEDDPAAVREVGMDIATEHAERMLSEGAPGLHFITMNRSTATIELRSRLAGQ
LG
>A0A6N2SX99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKLSEMMKEKQLLSFELFPPKTDKGMANLPGTIEKLCEFKPEYISCTYGAGGTNVGKNMD
VCKMIQDAGTVPVTHFTCIGNTREGIKDQLQNYLDNGVDHMLALRGDLPFGWTGTGGDFK
YATDLVAYVRKEFGDKIEIAVAGSPEGHISCRSLDADVAVLKQKQDNGADYIMTQLCWDM
EQFKRWQDKIDKAGVTMPVDVGIMPILDQAATINMALSRNACVMPRALCELISKYWIFPN
PFDKEPFDAAAEQKKADFKKAGIEYTIKQIDEYRALGVNGIHLYALNKWKDVTDIINESG
IRTLV
>A0A7X0MDF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium lusitanum|TrEMBL
MSSKTENGQSGIRISFEFFPPKSEEAEQQLWNTVADLTEWDPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLAAGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVAALRERGDFDISVSAYPEKHPESRDTSADVDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRAAGIKIPVVPGIMPIQNLTQLKRFAGACGTSIPSWLDERFAGTDD
DIELRAQVAAEVAAEQIQDLVRRGIDEFHLYTMNRSPLVSAVLERLGIQRKADTRAGAAA
>A0A3D4Q375|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrio sp|TrEMBL
MNDSQPRLSFEFFPPKTPEGKEKLIKVRDQLNEFAPDFFSVTYGAGGSTRDNTKGIVTQF
KNDGVSIAPHLSFGGDDEETIRALLQEYKDAGVDRIVALRGDMPSGVGGAYQLVYANELV
AFIRKHFGDHFHLEVAAYPEIHPQAKSYSDDVGYLKGKFDAGANSAITQYFFNPDSYFYF
VDQCQKAGITQPIYPGIMPIINYKNLTRFSDACGAEIPRWLRKALENYGDDEASLKAFGI
ELVTELCEVMLENEAPGLHFYTMNQTEPTAQIVKNLGLIPNE
>D0SMK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter junii SH205|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIQRFVEKVQAGANAGITQFFFNPDAYFYFI
ERLAKSGINIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1C5UQ74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MSLLQEVLERGEFAITAEMAPPKGTDLSHLLECAKKCVGRVHATNVTDFQSAVMRATSLA
TCKMLKDIGLEPVIQMTGRDRNRIAIEGEMLSAGVFGIENLLALTGDHTCVGDHPQAKSV
FDLDSVSILTTATTLNSGVDSVGLELKGKTNFYLGASVTPEYAPIEVQLLKMQKKINAGA
KFFQTQAVYDIDHLRKFRELTKNMDCKILAGIVPLKSPGMARFMTANVPGIFVPDDQIER
LKAAGKGNYVQEGIKMAGEFIRQIKEENLCDGVHIMAIGAEENVPLILDAAGL
>A0A315S478|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia marianensis|TrEMBL
MDTATDGPDAFTEYRGTRSRECPKRMVFGPCGGVRDDATCEMGAHICPFAVLTEPVPWPQ
PLTSPASPSELINASRTRPVVLSDLSVPAFDRGVLEQVASILGESSDAVLVGEHQNRPDY
PPTVMAQIILGVGGCPWVTLTCRDRNRVVLEQELMGLGQAGADGVFCVTGDGRAQGVRQD
VTQVFDLDGTRLAALAAQADLAVGVPEAPEAVPTGIRPARLLEKQRAGAQLAVLNHVSTP
ESLRAFMSAAREQGVTMPVIAGVAVYTDERSAQVLAAFPGLHLDHSQITRVLAADDSVEA
GIETAVDEAVALLDIPGVVGVNLSGLASAAGEVPAAKVKAEIGRRLRERLADGAQSVKAA
QW
>A0A3E0U3G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassotalea euphylliae|TrEMBL
MTYSHARQVESLNQSLSEISSDINVSFEFFPPNSPAMETTLWNSIERLAPLKPSFVSVTY
GAGSGTRDRTHDVIKRIQKETALLAAPHLTCIDAGREELVQIAKDYWESGVRHIVALRGD
LPDSSEKPSMYAADLVELLKSVADFDISVAAYPEGHPEAPNPQFDLLNLKRKVDAGASRA
ISQFFFDIESYLRFRDRCVSVGIDVEIIPGILPVTNYNTLKRFAGLTNVHVPSWMPKMYE
GLEDDETTRRLVGANIAMEQVKVLQKEGVKDFHFYTLNRAELTYAICHTLGIRPK
>A0A139NI00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. DD12|TrEMBL
MPGLLERLANEVLVADGAMGTLLYANGLDNCYESYNISRPEEVKRVHQAYIKAGADIIQT
NTYAAKRHRLKQYGFDQDAEAINRAGVALAREVAGEGTFVLGTVGASRGLRQCDLTLDEI
IAETLEQVSFLTSGDHLDGLLFETYYDAEELLAVIKAVRPLTDLPIVANLSLHEAGILEN
GQPLVEVMSQLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLAIQDDG
AYSFSSNADYFGQSAKLLVDEGARIIGGCCGTTPEHIRAIKRSIRGLEPVHRKVITPLPS
PDELIATAHRGHTLVDKVRKDITVIAELDPPKHLDITAFTQGVKALDQSGVSAITLADNS
LARTRICNLSLAASLKDEIDTPFLLHLACRDHNMIGLQSRLLGMDVLGFDNVLAITGDPS
KMGDFPGATSVYDANSFKLLQLIQQLNSGKGYSGASLKKATHFTVAAAFNPNVKNLARTG
RLIERKIASGADYFITQPVFSGEIIDELAQVTKPYDAPFFVGIMPITSYNNAIFLHNEVP
GIQLSESFLEKLEEKKDDKEACQQIALDESKALIDRALAHFNGIYLITPFMRYDLTVALV
DYINDKKKARKVG
>A0A6J6CYW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MLSVGSKEEAKEAGIDWAANLVRELVEAGAPGVHLYAFNQHESVTQVLQRAGIR
>A0A7C9JD92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Furfurilactobacillus rossiae|TrEMBL
MVADAEHQKLTDDGQRLTHTGEAQTEHPFLHPSVGHKSVLVEMDPPTTFKTASFYRGAER
LRDAGVDAITLADNSLAAVRVSNVAVAAKLKLEYGIHPIVHLTTRDHNLIGIQSEIMGLH
SLGIDDILAIAGNPAKAGDFPGATSVRDVNALGLIKLIKQYNTGVSPSGKDLDDRPNFCV
AAAFSPKITNGVLATRGIKRKIDCGADYLITQPVFDIARVNELADAFSQCGLQIPVFVGV
QPLMSKRNAEFLNEHVSGMSLPQSVLDRMAQAEIDGNEHEVGLQIAEEIADAICDRFDGV
HVVTPFNRYKMAAKLVTHIRQRENVAVNG
>A0A2T3G435|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacillus faecis|TrEMBL
MKINELLKKRPTLSFEIFPPKNNENDITSIYATIDELAKMNPDFISVTYGANGSTSKNTC
KIASTIKNKYGIESVAHLTCMNNTKEEIKDILTELKENSIENVLSLRGDYPKDGDGINHG
DFKYASELNSYIEENFPNDFCLSGGCYPETHYEARNFDEDLLNLKKKVDAGAKYLVTQIF
YDNQYYYRLVREARKIGINVPILAGIMPAHNPKQLRNIAKMSNCSVPFDLAAMIDRFAGN
PKAGKEVGLHYATYQIIDLMTHGVDGIHIYTMNKPEIAKEILKRTEYIRDEFFKD
>A0A7Y8I5T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriaceae bacterium|TrEMBL
MKVIEHLAKAKEPLISFEIIPPKRGGDIHGILSVLDDIIKYQPPFIDITSHSAEVEYEET
PTGIKKRVKRKRPGTLGICALIQNKYNIDAVPHILTKGFTREETEDFLIELNYLGIQNVL
AVRGDDNAYEKPIPEGRSANKTTKDLVAQIMDMNKGKYLEDSLLDAKPTNYCIGVGGYPE
KHFEAPNLKTDIKNCKEKLEAGADYIVTQMFFDNKFYFNYVEQCRNEGITAPIIPGLKII
SAKSHLINIPRNFYVTLPDELVDEITAARHEHVLDIGVEWAAKQVEDLLNKNVPSVHFYI
MLNSAPVKKLMNRLKLF
>A0A7C3ES69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanomethylicus mesodigestus|TrEMBL
MVDASSNLMRALKSGAFVFTGEVSPQKTSSTGALLESARSLRRCTIACNVTDNPRARANM
SSIAASHLIQEMAGVEAICQMTVRDRNRIALTSDLLGAASLGIRNVLTMTGDHTVLGDNP
GAKPVYDIDTAQFVKLIRGMVDAGIDLAGNKIDGKPLLHVGITANPNADPLEPEIAKIER
KIDLGAEFIQTQAVFDMENVKRFMGAIGSMGVPVILGIFICRSCSVAELINRNLPGIKIP
DELVSSLKKAESNGGRANGEVDRINVDYYGGLIREIRKTTSAAGVHIMAINYDRIVNALY
EELKSELSLTF
>A0A6J6D289|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSTHAAVQAERATGIPFSFEVYPARSESQVESVHETVQKLAAVAPQFIAVTYGAGGSSRD
RSLDLVRYILTETNVPPMAHLTCVGSTANEANRLVRDFLDAGIRQFLAIRGDAPEDAIES
EDFLGDLRSATELVQLIHRVQSEREPYTEVDEPQWGGGAVRLSQRREPVRIGVAAFPNGH
PQSRNRAQDIDVLLAKQAQGANLAITQLFFDADDYLSFMVDARAAGVDFPVIPGIMPVTS
LGRLNRIVEITDEPMPVHLEAALGSASDAAAQYEVGIAHATELARAVLDGGAPGIHLYAF
NQHAPVLDVLTRLGAID
>A0A6N6SM53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriaceae bacterium|TrEMBL
MKVTEILASTKEPLISFEIIPPKRGGDIKSLLNTIESISHYKPPFIDITSHAAEMVYEET
ANGIKKKVIRKRPGTLGICALIQNKYHIEAVPHILCKNFTKEETEDFLIELGYLGVNNVL
AIQGDDKGFEKTVSEGRTTNKHAIDLVKQINDMNHGVYLEEGLLDAKPSDFCIGVSGYPE
KHYEAPNLKTDMMYTKQKIDAGAEYIVTQMFFDNQAFFRYCNLAKEMEINAPILPGLKIL
TSKAHLTGIPKNFYINVPEELTAEIMEAKPEHVMEIGVNWAAKQAEELINAGVSCLHFYI
MQNPKPVDMLMKKLGF
>A0A6J7DXB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTRTPSIVDRLRTEPEARIPFSVEFSPPRDEAAEARLWQAVREFEQLQPAFVSMTYGAGG
STRDRTVRVTGQIAEETTLLPVAHLTAVSHSVAELRSMVGSYADRGITNILVLRGDPPGD
PLGEWEKHPEGVEYAEELVRMVRELGDFHVGVASFPEGHHRADDLEQDTRCLVGKLRAGA
EYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSVRRMLELSGTTLPSH
LDEKFTRAAGSGAEEDKAAVREVGIELATNIGERLIAEGAPGLHFITLNFARATREVLSN
LGLAAARV
>A0A2A8CQJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRLKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGILISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6J7JCF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MAKVGEAVTYSFEFFPPKDQEGEDRLWSAIAALEPIKPDFISVTYGAGGSTRDRTIRITS
EITEHTKLPVVAHLTCVGSTRDELLEILARYKDAGIHNILALRGDPTGGPRAPWSPTPGG
LNHADELVSLAADFGGFTIGVAAFPDGHPASNGDFAVDIDTLIRKEAAGATFATTQFFFE
VDKWKSLVDKLAARGSQLPIIAGILPVTNVNQLNRMSELSGTPIPGAMSDAFEKIKDKPD
DVRKLGVDLATKLCEDLLAAGVPGLHFYTMNTSTATREIFALIKDKKRA
>A0A1B8DE08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. 24MN13|TrEMBL
MHIKDMLNQGEQAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHA
QLTCEMVSVAQSVYGLETCMHLTCTDMGKEKVDDALKNAYKGGCTNILALRGDPPREKEK
WVATDEGFQYARDLVKYIRKTYGNHFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATF
IVTQMFYDVPNFLDWVRKVRAKGITIPIIPGIMPISTYASFLRRCNHMNAKIPPGWIEAM
EPVKNDDAAVREIGRGLVTDMCRSILESGINHLHFYTMNLAQATRGVLEQLEMLPSEERP
LKQALPWRQSLGLGRRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGEPKSVKDIANVFLRYLNADIESLPWSEAAISNEADVIKNQLVE
LNERGLLTINSQPAVDGVKSSHPVYGWGPANGYVYQKAYLELLVAPELIDELLDRIARDP
EVTYYAVTKSGTLRTNAPSDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHDSSSPSRNVIQRVMETFYLVNIVHNDFHQRDALFSLFEGLTVPNIDKAAAPATNGD
KVEEAPPAIVSNVLPVA
>A0A517DNU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa termitida|TrEMBL
MTVKLSFSEALADPAQLSVTWELVPGRGAREKAQEHLVKMAELAAKDPRINAITITDNPG
GKSAIAAYAMAVEAKQRGIDPLVHFTSKDKNRNALESELYALGRADIQNLLVMTGDYPGA
GYAGSAKPVFDFDAVHALRMITKMNAGDYSKLPATNFFAGAVVSPFKSTEAETMAQYYKL
HKKLDNGAKFIITQLGYDARKFDELRKYVDSNRLAVALVGNIFVLSLPVARLMNQNLIPG
CVVTDSLVDKLAAEAAQSNKKELQLLRAAKLYAVLKGLKYDGVNIGGHGLGYTEVQYIME
KGEELSADWQEIAAAEFDHPQAGGFYFFEKDQATGLNTCQPAKRSQTGSSLKQSLMDVVH
GVAFDPKAPLYPVNKAIAKFVDKSWLKQPFTLAEYTTKTVTNECRFCGDCAMHELGFICP
MSQCPKQQRNGACGGSRDGWCEVYPGQQKCIYVKMYEGFKGQGKEERMKSKYMAPCNWDL
HRTSSWLNYFNDRDYNSSKD
>A0A559LTN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. cubense|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDDVKGDDERVKMVGVDIVSELIDKIKTIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSPVRLRMP
>A0A1F4GXH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium GWF1_66_17|TrEMBL
MALPVSFEFFPPKTPEGAEKLRAVRQQLYGQKPEFCSVTYGAGGSTQQGTFDTVGAILAE
GVDAASHFSCIGATKASVREQLTTLKAMGVKRLVALRGDLPSGYGIGGEFHYASDLVAFI
RAETGRDFHIEVAAYPEVHPQAKSPESDLQAFATKVRAGADSAITQYFYNSDAYFRFVDE
AHRLGVDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDIASIKAFGLDVV
TDLCDQLRNAGVPALHFYTMNQSVATLEIVKRLELG
>A0A1V5SXM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium ADurb.Bin276|TrEMBL
MSWLKQVLQSGHFAVTAEVGPPKGSDPQVIRKKCDLLKGFVDAVNITDNQTAIVRMSSFA
SCLIAQKQEIEPVMQMVTRDRNRIALQSDFLGACALGISNLLCLTGDHQSMGNHPQSKNV
YDIDSIQLLQIFKNMRDQKVFQNGEEVKGEINVFLGAGESPYADPLEFRALRLAKKIAAG
AEFIQTQAIFDVDIFTQWMEEVCCLGLHKKSFILAGVIPVKSAKALRYMKNEVPGVVIPD
NLIERMEAATDQKAEGVEVCIETIQKVAKIEGVSGVHIMAIAWESIVPEIVQRSGLLPRP
AKGEITSS
>A0A1V4EA40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. GKU 895|TrEMBL
MNTLRDILDRGTPSFSFEFFPPKTAKGERTLWEAIRRIEPMAPSFVSVTYGAGGSSRDRT
VEVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGDPNAPWI
PHPDGFTHADELVRLVKDSGEFSVGVAAFPERHPRSADWDSEIRHFVAKCRAGADYAITQ
MFFRVEDYLRLRDRVVAAGCDTPIIPEIMPATDVRQIARFAELSGAAFPEDLAHRLDAVR
DNPAEGHRIGVEYATAMADRLLAEGAPGLHYITLNRSTATLEIHRNVTNSRSAQHALAAQ
R
>A0A329N2L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinomicrobium sp. N-1-3-6|TrEMBL
MKVTEHIEKAGGKTLFSFEVVPPQKGKNIQDLYDNIDPLMEFRPPFIDVTTSREEFVYIE
REGLLDRRIVRMRPGTVGICASIKHKYQVDTVPHVLCGGFTREETEYMLVDCHYLGIENV
MALRGDAMKHQRYFEPATGGHTYANELVRQIKDITRGKYLHDTVEAANKPDFCIGVAGYP
EKHLEAPSLDYDLKKLQEKVDAGADYIVTQMFFDNKRFFEFVERAKAMGINVPIIPGLKP
IAVKRHLQLLPQVFKIDMPEDLIRAVEQCKTNKEVRQVGVEWCIQQSKELKEAGVPVLHY
YSMGKSDNIKAVASAVF
>A0A521V948|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospiraceae bacterium|TrEMBL
MKVTDYFANAQGQTLVSFEILPPLKGGGMSAIFETLDPLMEFKPPFIDVTYHREEFVYKK
MPSGYFEKIAIRKRPGTVGICAAIMHRYGVDAVPHLICGGFTKEETENALIDLNFLNINN
VLALRGDAQGFDDKFIPEPGGSKFALELVKQIVDMNHGKYLDDNIENGAKTDFSIGIAGY
PEKHFEAPNLQLDLEFAKAKVDAGADYIVTQMFFDNKKFFNYVAECRKA
>A0A2N2GQZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-3|TrEMBL
MLVKDILGNNRFSFSFEFFPPKDEPGWENLFANISDLMPLKPAYVSVTYGAGGSTRDRTH
KLIVRIQQETSLTVVSHLTCVGSNRTETGEILRNYAASGVENILALRGDPPKGQRDFVHP
PDGFAYAADLVAFIKKNFPHMGVGVAGFPEGHPATPNRLLEMDYLKAKVDAGADYIVTQL
FFDNRDFYDFRDRCALAGITVPIIAGLMPITTKSGMVRMAELAAGARIPAALLRALDRAR
SDEQVEKVGVHWATEQVRDLLDNEVRGIHFYTLNHSRQALEIYQALGVEDSIQLGA
>A0A3N2PVY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sodiomyces alkalinus F11|TrEMBL
MHIKDMLREAERDGQPSFSFEYFPPKTAQGVQNLYDRMEKMYHMGPKFIDITWGAGGRIA
ELTCDMVLQAQSIYGLETCMHLTCTDMGLEKVNDALHKAYKAGCTNILALRGDPPRDKEK
WVAADEDFQYARDLVKHIRDTYHDNFDVGVAGYPEGCDDNKDEEQLLDHLKEKVDMGATF
IVTQMFYDADNFVRWVGKVRERGITVPIIPGIMPIATYASFLRRAKHMNCRVPDEWMAAL
DPVKNDDVAVREIGKHLVADLCRKILSAGIHHLHFYTMNLAQATRMVLEELDWLPTSERP
LKQRLPWKQSLGFGRRAEDVRPIFWKGRNKSYVLRTKEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPQSVQDVADLFVRYLKREVDSLPWSESPLTAEASPIRDDLID
LNKRGLITINSQPAVSGVKSSDPVHGWGPPNGYVYQKSYLELLVHPDLYPELIARIEDHP
DMTYYAVTKDGTLKYNSPTDGPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGVDW
AHCYDPESPSRVLIERIMNEWYLVNIVNNDFHQQREIFEIFQGLSVKEYDDIKPVSQNGE
SANGVATAST
>A0A4R4QCC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. KC213|TrEMBL
MALGLPSVLPNPQPAIGELIRRDAPTFSFEFFPPKTPKGEQLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGAGVRNVLAVR
GDPPGDPGGEWVRHPEGVLYAEELVRLVRDAGDFSVGVAAFPYKHPRSPDIASDVAHFVR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQMATIERSVQLSGAPF
PPALAERFARVAHDPEAVRRLGVEQASEMCARLLDEGVPGIHFITLNRSTATREVWRSLQ
AGARV
>A0A8J6NS95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfatibia profunda|TrEMBL
MKSGSNLEKVLRAGHFAFTGELGPPRGTDGEEVREKTKFLKGNVDAVNITDNQTAVVRLA
SWAACLILIQEGLEPNFQMVCRDRNRLAMQADILGVYCHGVRNMLCLSGDHCMFGDHPDA
MGVFDIDSIQLINMVKTMRDEGKFQGGADVHHPPKIFIGAAVNPFADPFDWRVHRLAKKI
EAGVDFIQTQCIYNMDKFRKFIQQANDMGLTEKVFILAGVTPMKNIGMARYMQKKVPGIE
VPEELIDRLKGVDKKNVANEGIKIACEQIEEFKEMKGVHGVHMMAIEWEHMVPEIAERAK
VLPRPVMK
>A0A439YN38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETAIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGG
PYRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A1M5PCB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobaculum gomorrense|TrEMBL
MSLESPPTTDEGVQQLLAEPKFELMPFDSMAEQLDQLPDGATIAVTTSPTLGIGATVEWT
ETAAEQGYEMVPHIAARYVEDTDHLEEIARRLTEAGVTDIFVPGGDREEPAGEFTSAQEL
LVALDDLDYEFEDVGITGYPEGHEFLSDETLAEAMEKKEPYATYIVTQLCYDPDAVIAWI
EEIRERGVDLPVDVGIPGVMKYQKLLNISKKVGVGDSVKFLRKTTGVLGFVKQLIGSRGM
YTPDRLIDGLAPYVGDPEYGLRNVHVYTFNQSADTEDWRYGRLDE
>A0A3S3FM14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MSIRHQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQIF
LGAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>A0A285V9N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus aggregatus|TrEMBL
MTQTVRELLASERPTWSFEFFPPKTPEAEPQLWTALRELERLRPSFVSVTYGAGGSTREG
TVSVTERIATETTMTPMAHLTAVDHSIAELRHVVSRLAAAGVRNIIALRGDPPGSDPQAE
WVAHPEGLSYAAELVELIKSMGDFSVGVAAFPERHPRSPDFDTDIDMFVAKCRAGADFAI
TQMFFRAEDYLRMRDRVAHRGCDVPIIAGVMPVTSARQIKRIVQLSGQAFPADLAERFEA
LDGERPEDKAAVRAFGVEVATELCSTLLDEGVPGIHFITMNRSTATRDVYTNLVGNPSIT
TPS
>A0A417LNQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium TM09-10|TrEMBL
MIKDLFSQKQTLSFEVFPPKKDDEFTNAQNVLHQLSELQPDFISVTYGAGGSRSKRTVEL
ASFIQNSLHIPAVAHMTCVGSSKEDILAVTDDMKQAGLSHVLALRGDRPTWMDDAQFENR
AFAHASDLTRFLKEHTDLEIAGACYPEKHFEAESLDTDIAYLKEKQEAGAAFFITQLFFE
NDSFYRFLEKKNHAGITLPVCAGIMPITSAKQLGTTVTLSGSSVPKELADIIATYGENPE
DMRKAGIDYAIRQILDLKQHGVDGIHIYSMNKPKTTRTIVEAIR
>A0A1F0YZC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC068E02|TrEMBL
MTTVHPALSFELFPPRSHASCESLLHTIAELEGTNPDYVSVTYSGDAKRRQKTLALLDHM
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQDSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSARLAGVDIPIIPGIMPVTSLKRLRNLCQMAGMEVPTDLAYALETATSSAE
LHRIGVEYALNQCRTVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEY
A
>A0A5C8MHP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parageobacillus sp. SY1|TrEMBL
FKETALAFREQGVRLIGGCCGTTPKHIEAIANALTDRTPITEKVVKQRHVPISIQTNEPN
AAPPLQDIVRKRRSVIVELDPPKKLGIAKFLEGAKALKEANIDALTLADNSLATPRISNM
ALGSIVKEQLGIRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIGDFPGAT
SVYDLSSFDLIRLIRQFNEGLSYSGKSLGQKTNFSIAAAFNPNVRHLDKAVERLEKKIQC
GAHYFITQPLYSERQIEEVYEATK
>A0A1E3QGI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lipomyces starkeyi NRRL Y-11557|TrEMBL
MTTIIERIAALKPEEPFFSFEFFPPKTDSGVQNLVARLRRMAQLNPLFVNITWGAGGSTV
SKSLDLATLCTSELGLTTCLHLTCTNMEKNIIDEALSKAKQHGIRNILALRGDPPRGVEY
WTPPESQEFMYAVDLVRYIRQEYGDYFCIGVAAYPEGYADGSNPEAQDPKIDLPYLIEKT
AAGADFIMTQLFFDTDKFLAFEKMLREHESGIFETIPIIPGLLPINTFQSFIRTAKLSHA
HLPDSVLEKLDSVPSTDDEQVKQVGVEILVEMIDRIYNETQHRVRGFHFYTLNLERSVAL
ILDKSNVVKTPLRLKLVSQGTEKKIEKPVSIESVLSDGVKDVKITEKVAVAVPASEVSMT
SEASWDDFPNGRWGDPRSPAYGEIDGYGITLHVPAKKALELWGSPETIADISGLFVQYLK
GILPVLPWSEEEGLSPETKLIEADLIRLNKLGLWTVASQPAVNGVRSDDKVFGWGPRNGY
VFQKALIEFFVPENMWFTLKEKLQIGDSVSYYAGNCRGDFFSNMNANDVNAVTWGVFPNR
EVVQPTIIEEQSFKAWSEEAFAVWKEWQRLYPRGSATSNLINTIHESYYLVSIIHHDYVN
TNALWNFLQL
>A0A442MZ56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILC
GVGPLASAKTAKWIRSHVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A2E7WN05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MGRLAEALKASPFVITGELTPPKGTDLGDLFTKAELLREHVTAFNLTESHAARMAMDPVA
VGHLLIDRGVEPIVQMTSRDKNRLAIQASILGAAALGISNXVFMGGDPPKNGDHPDAKPV
FDLFASQLLEAASALNAGNDLTGNPLKGVPQLTIGAVANPGAXDIDTEIDNMKRKADAGA
EFFQTQAVYDTEAXGRFMDRAKPDKTVLAGIIPIKSVKMARYMNDRIPGVDIPQQLIDRI
DAAGDDQAQITEISIEIASTTVRALRSMTGGVHVMAIGWEDKVPAILDRSSA
>A0A2D6K9S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MYFYDEPIPGAPLPILPGHVSNGRFERVLRAGKFAVTTELAPPDSVDRNEVYRLARVFDS
YVDAINVTDGSGANCHMSSLAVSALLTRVGYSPILQVSCRDRNRIAIQGDLLGGATLGVS
NVLCLTGDGVDAGDHPEAKPVFDLDSVSLLGTVKIMRERSSFLSGRQLDSAPRFFIGASA
NPFVPPYDYRPLRLKKKIDAGAEFIQSQYCFDIDRLVTYMNQVRDLGLDKRCFILVGVGP
LASARSAGWIRDHVPGVVIPDAIVSRLLSAKDQRREGIKICIEMIQQIREIEGVAGVHVM
AYRQEESVAEIVKTSGVLEDRVPWHPQRDQFAAGPRLAEEKNECN
>F2S694|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton tonsurans (strain CBS 112818)|TrEMBL
MHIKDKLALAEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMPREKVDDALQSAFKAGCTNILALRGDPPREKEA
WEQTEGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFLDWVKKCRQAGIKVPIIPGIMPISTYAAFIRRTNWVKCAVPKGWMEAL
EPVKNDDAAVKQIGKALVSEMCRKLLENGINHLHFYTMNLAQSTTMVLEELNLKPSTETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSVRDLSDIFVRFLEHKLDRLPWSESAITQESEIIKDDLID
LNNRGFLTINSQPAINGAKSSHPIYGWGPRNGYVYQKAYLELLISPALIDEVIRRIESNA
DLTYHCINKDGELKTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSASRKLIQNTMDTWYLVNIVNNDFHKTHDIFDLFKGLVLKDIDTEVSGTQQATE
LAENGTHSEAPASKSEKQAVSAN
>A0A5P2UEV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces subrutilus|TrEMBL
MPAATAVTAPRPRTSAPTPLGVRELLAQGRRTFSFEFFPPKTDAGERTLWAAIRRIEPFA
PSFVSVTYGAGGSSRDRTVEVTKRIAAETTLRPVAHLTAVGHSVTELRHIIGQYADAGIR
DVLALRGDPPGDPKGEWTPHPHGLTHAAELVTLIRQLGDFTVGVAAFPERHPRSPSWCED
ITHFAAKCRAGADYAITQMFFHAEDYLRLRDRLASVGCLTPVIPEIMPATDFRQISRFAE
LSDARFPDALARRLEAAKDNPADGHRIGVAYATAMSERLLAEGAPGLHYITLNKSTATLE
IHQNLNVSQTPATTTTE
>A0A4V2NL94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella soli|TrEMBL
MAQISFEFFPPKTDEQREQLDRAARSLKARGPEYVSVTFGAGGSTLSYTGETVARLHRQH
GLDVAPHLSCMGGTRTEIAELLDAYRAAGYRRVVALRGDLPSGMATPGDFRYAAELVAFI
RQHSGDHFHIEVAAYPETHPQADDALADLRHFKSKVDAGANGAITQYFFNADAYFRFVDD
VQRLGVDVPVVPGIMPISNFSQLKRFSDACGAEIPRWIAKRMQAHGDDADAVRELAADVV
AQLCQRLLDGGAPALHFYTLNRAKATISILDRIGI
>A0A442BEB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDAVIREFVDFGVTRFVALRGDPAAGVGT
IYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
AGSAAA
>A0A529CGX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTMTPAAHMTCVDAARHEVDAVIREFADMGVKRFVALRGDPAEGVGA
AYRPHPEGYANGAELVDALKGAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEVEAA
GSAAA
>A0A512AHZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sediminis|TrEMBL
MWGALLVAAALIHPNWDKPPLGITDGFSLEMTAKDEASLREAAPLIPVDTPVAVTFLPGE
DVAARVKATVAVRELGFEPMPHFSARRITSEDDFEGYLKAVVEQAGVQRAFIVAGDPPEP
VGPYFDTSALIATGAFERSGIKAIGIGGHPEGHPNMTEQQCWDVLVKKVTEIEARGMAPL
IVTQFGFDPDAFLAWLLKLRALGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLRKY
GISVTNLLGSAGPDKLVDAFAKGLGPQHGRVRLHFYPFGGMVKTLEWIQAYNAKHGISA
>A0A528L396|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMESRLWDTVTRLEPLRPEFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDTVIREFVDFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>A0A2E1WGX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEKLKEYKNQGKTFYSFEFFPPKSDFGLDNLYSRIDRMASLRPAYIDITWGAGGSTS
DRTLKMSKIIQKYFGLDVMMHLTCTNMPKDSIRQVLLNAQKNNISNILALRGDPPEGSTI
WEKDDQGFNYGIDLVRYIRKEFGDNFFIGVGGYPESHQEQNDIDLDISFLKKKVDAGSDI
IITQLFYDVDNFLIFRDKCSDVGIDIPIIPGIMPINNYARFNKFTQFCKVSIPKSVKSAL
EPIKNDDSSVIDYGIEQASNMCQKLIAEGVPGLHFYTLNLEHSVTEILSALGLVSTKGPD
KPLPWRQSTVVERKSTEDVRPIFWSNRPVSYLTRTETWDDFPNGRWGDITSPTFGELNQY
XAIRAGSKXDKXKARKRKLWGEPRSIKDISEIFVSFXEGKXGSLPWCETPLAIEXXXIXK
DXVKLNLXGYLTINSQPKVNGLXSEDPNFGWGAKGGKVFQKXYLEFXTSKXKLXQLLXIL
DQXKNXSYQAINXXGKXISNLSEXNVNAVTWGVFPGXDILQPTIVDARSFLIWKDEAFDL
WINDWANIYKKNSESYKLLHTIYDNYYLVNIVDNDFIDGNMINHILVK
>A0A143BIB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonas phototrophica|TrEMBL
MTTVSEQHIAANSLAEDSPRAALLTRLLDPEQVVMFDGAMGTMLYARGVFINQCYDELVL
RSPDLVREVHAAYVKAGAEVVETNTFGANRTKLAQYGLEGQVVAINQRAAQVAREAAGEA
RLVAGAVGPLGVRLEPYGPTSRDEARGLFREQMQALASGGADCFVLETFADLDELEQAVL
AAREVNAAMPVIAQATVGPELRTAFGATPEDVARVLDKWGVDVIGLNCSVGPQTILEAIE
RMAAVTHKKLSAQPNAGMPRDVGGRTMYMASPEYMASYARHLIQAGAKIIGGCCGTTPEH
VKAMVEGVRPLSPRTRVQVGATREAEVSGEPDKSREPVPLAQRSRFGAKLAAGQFVTSVE
IVPPRGVDTVKLEHDAAALAKAGVDAINVPDGPRAQSRMGAIATSLIIERHGIEAVTHYA
CRDRNLLGMLSDLLGASALGLRNLLLVTGDPPKMGPYPDATAVFDIDAIGLTNLVRNLNR
GMDPGNNPIGDPTRFVIGVGVNPVAIDPAHELKRFHWKVEAGAEYAITQPVFDPAQLESF
LESIHDVRIPVVAGIWPLVSARNAEFLANEVPGVTVPQEILDRMRRANEKSKEHALAEGI
AIAREALDRVRGSVQGVQVSAPFGKIEYALEVFG
>A0A2E8GWR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEKIANYKTQGKTFYSFEFFPPKTDFGLDNLYSRIDRMASFNPAYIDITWGSGGSRT
DKTLEMSKTIHKYFGLEVMMHLTCTNMQVASIKKILIEAEKNDLSNILALRGDPPEGSST
WAQHENGFRHGVDLVRYIRKEFGDHFFLGVGGYPEGHQEQSNLDTDISFLKEKVDAGADI
VVTQLFYDVDKFFVFRDKCIKAGIKVPIIPGIMPIHNYARFLKFTQFCKVSIPDSVTAQL
EPIKYDDSSVINYGIDQATAMCQKLIENGVPGLHFYTLNLEHSVSRILQSLGLVASQGTI
KELPWRQSTSDDRKTSEDVRPIYWSNRPVSYLTRTEIWDDFPNGRWGDIXSPTFGELNQY
HAIRAGSKSDKIRAKRKKIWGEPKSIKDITDVFVSFCKGKINSLPWCEMPLAQESKQISD
DLLNLNKMGYFTINSQPKINGLPSEDTEVGWGGLGGRIYQKAYLEFFTSKDKLDRLLKSV
RSKENISYEAININGDLITNLPENNAMAVTWGVFPDKEIIQPTIVDTRSFLIWKDEAFSL
WMNDWASIYKVKSESYKLIKEIYDTYYLVNIVDNDYVDGDLMQQILKS
>A0A7C7GSR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiaceae bacterium|TrEMBL
MTNADRTYSFEFFPPKTDKGVDNLKATRAKLAKLKPEYFSCTFGAGGSTRDRTFETVVDI
QEETSIDAAPHLSCIDSTRDNIAGMLQGYHDKGIQRLVALRGDIPSGTVVVGEFRYANEL
VSYIRETTGDHFHIEVAAYPEIHPQANSARDDLINFKRKIDAGANSAITQYFYNADAYFR
FVDGCRDQGVDIPIIPGIMPITNYVQLARFSEMCGAEIPRWLRKRLADFGDDMDSLKAFG
IDVVTEMCRQLLDGGAPGLHFYTLNQASASIKIWDNLSLSD
>A0A2D8MRT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIRDKVKKPQRPVVAYEILPPREKDGTLNSYAETISSLLSQTHIDAINIPEVHDEIGRG
DRPVTNQKRGEPREFGMLLQDIVGIEAIINRVVVHEPYEEQMRWIEETNTTYEIENMIIV
GGESSKVDYPGPTVNEMLQSIAKRSNSNGGDIFCGGIAIPSRKDESKNLIRKSEHGSEFF
TTQVLYDAENINKMINNYQSRCNELDTFPRRILLSFAPVSSQKNIEFLKWLGVEIPDDTE
RYLKGRPGSMTERSLDVAVEVLNEILDFITVNNLKVPVGLNVEHIMSYNFQSSVEMLQEL
ARIYREFCIKTQQYS
>A0A549T6Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium straminoryzae|TrEMBL
MNPVAKAPRSESALRVSFEFFPPKSPDMEQQLWQTVCELARYNPDFVSVTYGAGGTTKAP
TFSTVERMIGEMRLPTASHLTCVDADKAETHQVIADLRKLGVRHIVALRGDPASGIGTAY
QPHPQGYANAAELVAGLKEIGGFEISVSAYPEKHPESADVSADIAMLKRKADAGADRALT
QFFFDNDVFERYLDQVRAAGITIPVIPGIMPIQNLTQLKRFASRCGSTVPAFLDARFEGL
DDKPEDRAKVAADVAAEQIEDLMRRGIFDVHLYTMNRTPLVAGVLHRLGILPVEAAQAGA
AA
>A0A2D9Z054|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIRDKIKKPQRPVVAYEILPPREKDGTLNSYAETISSLLSQTHIDAXNIPEVLDEAGRG
DRPIANXKRGEPREFGRLLQDIVGIEAIXNXVVVHDXYDTQMRWLEETNLVYEIENMIIV
GGESSNVXYPGPTVXQXLEAISXTYXXXGKDXFCGGIAIPSRXEESKNLIKKSKNGSEFF
TTQVLYDSKNIIKMMNNYQTRCNELNTFPRRILLSFAPVSSQKNIDFLKWLGVEIPEGTE
KYLQGRPGSMKERSLDVAIEVLNEILVNIEENNLKVPVGLNVEHIMSYNFQSSVEMLQEL
ARIYREFCIKTQNYSI
>A0A2E0HXF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVTEFLENKNKTHFSFEIIPPFRGGSIDTVFSLVEDLMRFDPPFIDLTSRSAEEYYQDD
GDGNLVQHIRRKRPGTIGMSAAIKNKFNVETVPHLLCSGFSKEETEDALIELNYLGIKNV
LAVRGDELRNDHNLSKSKNSNFYASDLVKQIKDMNEGRYLEPLIDPFKSDFCIGVGGYPE
KHFEAIDLKTDISHLKEKVDSGADYIVTQMFFDNKVYFDFVDKCRDEGIEIPIIPGIKIL
STEKHLTALPKHFFIDLPKELKDLTQLKTKNEIRNAGKKWAIKQIQELIERDAPCIHLYI
MASSKLASEVVSEFI
>A0A5R8WSQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter jeollabukensis|TrEMBL
MKVTEHLTRANGKTQFSFEVLPPKKGENIQTLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFVPEPDGHSYACDLIGQVSDLNKGAYLDEEQDDTWATDFCIGTAGY
PEKHFEAPSHAADLRYLKHKVDRGADYIVTQMFFDNEQFFSFEKRCREAGIHVPIIPGLK
PITTKAQLTALPRSFFLNLPDELVDTIHRAPDNAAAREIGIEWCINQSRELMDHGVPVLH
YYSMGKADSVRRVAAALF
>A0A3D2FQ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIEFLEKANKTLFSFEIIPPTRGGSIDRIFNLVETLMPFNPPFIDLTSRSAEVYYEDA
GEGKMIRFIRRKRPGTIGISAAIKNKFNVETVPHILCRGFTREETEDALIELNYLGINNV
LAVRGDELRKDAPDTPGKTRHRYASNLVKQITDMNDGKYVEELIDAVPTNFCIGVGAYPE
KHFEAPNMATDIKYLKAKVDAGADYIVTQMFYDNKAFFKFVEDCRSAGIDIPIIPGIKIL
STEKHLSVIPKNFYVDIPEALSEKVIGQSKEDIV
>A0A2R7II02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. HMWF023|TrEMBL
MTAISFEFYPPKTDEQRTQLDRAAAKLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAQDALLDLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VQRLGVQVPITPGIMPISNFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGAEVV
AKLCQRLIDGGAPGLHFYTLNLAKPTVSVLTLLRG
>A0A660XIE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MQSDLLGASVLGIKNILAITGDPPMIGTYPQSSAVFDIDSIGLTNLLTNLNRGLDLGNKP
IGDPTAFFIGVGVDPNSINLDKEIQRFYWKVDAGAEFAITQPVFDPVALEQFLEKVKDFR
IPFI
>A0A2N1DV82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLKNFVRKADAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A4Y9JXT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribacter muris|TrEMBL
MSYAKEIDLLNQSVADLNGNINVSFEFFPPKNEKMENLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKTIQQQTGIISAPHLTGIDATPDELRQIAQDYWDSGIRHIVALRGDEP
PGYTKKPFYASDLVALLKEVADFDISVAAYPEVHPEAKSAQSDLLYLKQKVDAGANRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLENMAKITNVKIPSWMPKMYQGL
EEDQTTRNLVAASIAIDMVKVLSKEGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A438M0T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea polychroma|TrEMBL
MALGRPSIRPDRVPTVREMLASGGRTFSFEFFPPKTDEGERQLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERIAHGTTLTPVAHFTAVNHSIRELRHLIGRFADAGVRNILAVR
GDPPGDPTAEWVQHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIEADTEYFVR
KCEAGADYAITQMFFQAEDYLRLRDRVAARGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPEVAARFEEVADDPGAVRRLGIDHGAELCQRLLDEGAPGIHFITFNRSSATREVFQRIA
PITLSA
>A0A4T2BXS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Subtercola vilae|TrEMBL
MCEPWSHPNSRPSCSSSARTDRLLSQRVTHELRAWLGCSVADVRRPAHIWGRKATAEPGT
RPRYALHAEPLSLPAVFARVIEGPVVIPFSFEVYPPRSAAAAAELPATIDALAAAGPEFI
SVTFGAGGSSRDSSLEALRYVRENTAVKPMAHLTCVGSSHAEAGLLIRRFLDAGITSFLA
LRGDLPHDVDGAAAPLGDLGSAGELVQLIHRVQAERVPYTEVQLPGLPHAAQVDRHRAKV
TVAVAAFPNGHPRSRFDGQDVDALLAKQAAGATLAITQLFFEAEHYLAFVDRARAAGVTI
PILPGVMPVTSASRLRRIAELAELTPPPRLLAALEAAGTDEQRFAVGVENAVALASAVTA
GGAPGIHLYTFNRHEAVLTVLAELGLVPASAPKYGTRNKESA
>A0A427LIC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter soli|TrEMBL
MSSLASYFQQRQFCVLVEYLTSLTPYHPLQTEIAGYPTVMALADRVHSDHDLAPLDASRT
YDSAVEKLLHFSGKDRDIQDFEAFLAQAKAANIQNLLLLSGDKLKSHSDGTDGRPRTRYL
ESVNAVAAAQHVGGFHIGVALNPFKYVEAERDAQYLKLHKKLKAGADFIITQLGYDIKAL
QQAKAFLTSHDYAQKIVACVMPLTLARANYMIKHKVAGIVITPHMLNVLKHEKQTGQTAH
VYARCALQILICEQLGFAGVHLSACHKPDEQARLAEYIEEYRHLDLAALEQHYKRLWHIQ
TGLELQPERLPSARKPSRLEVVKYRHLQFMHDALFMSKPAKNAGRFIFKAAFWNTHLMTK
MLLKTESFSKHRLVGCESCGQCRLADTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVEQTQILKDKLIPTVPIATRGSSSWKNWYLAVEA
>A0A559J2Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. N4|TrEMBL
MNTSQYEKFRQAIQNQLIVGDGAMGTYLYQLGYPVGKSYEAMNISDPDIILGIHREYVEA
GATLLETNTFTANREKLAKHGMEHLVKDINRAGVRLAREAAQGKAFVAGALGSIRAGKRE
NISTEQVVRDFEEQLSALIEAGVDAIMFETFYDLEEMRLAFKIARQIDNNVPIICQFAVE
DSERTKDGFTLPEAFRILREDGADVVGFNCRMGPNGLLRAIESVESMVGLPLSAFPNAGL
PDYVDGRYNFVATAEYMAQSAVEFANKGARLVGGCCGTTPEHIRAIVSALETVKELPSLA
IKNNRAKLDISVGTELPVGASSSSNKDWNKQPTIVDLAKERHTVIVELDPPRDLDIAKFM
RGAAELKRAGADAVTLADNSLAVTRMSNMALGYLIKEEVGVRPLVHIACRDRNLIGTQSH
MMGLDALEMDHVLAVTGDPARFGDLPDSSSVYDLTSFEIIRMIKQLNDGVAFSGRPLKQK
ANFVVGAAFNPNVKHLEKAVERLYRKVEAGADYIMTQPIYDPVLIERMAELTKSISIPIF
VGIMPLASGRNAEYLHNEVPGILLSDEVRSRMAGLEGEVGRTVGVDIARDLLDVAMKHFN
GIYLITPFMFYEMTAELTSYVWEKAERPANLLSR
>A0A0U2J808|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus rifietoensis|TrEMBL
MMLLDELKKRMLTADGAMGTLLYSYGIEYCNEELNIQRPEVIEKIHRDYIAAGADIIQTN
TYGANAHKLARYGLEEQTEAINKAAIAIANKAAKDGGQFVLGTIGGIRGIRKSDATLDEI
VAMVDQQAQHLLSGDPDGLLLETYYDFEELAATVSHLKKLTDAPLIAQLSMHEPGILQNG
MSLNEGLKRLDALGAEIVGVNCRLGPHHTIQAFEGVELPEKAFLSAYPNASLLDIEDGRI
VYESEADYFGRAALLLREEGVRLIGGCCGTTPKHIEAVKKRIGHLQPITEKKVEEKKPIV
IREAEALKDKPLHEKAKTERTIIVELDTPRHLDVEKFLEGSKALDAEGIDAITMADNSLA
SPRISNMAMGSILKHKQDVRPLAHITCRDRNLIGLQSHIMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSLELIQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVVERAVQR
LEKKIEAGADYFISQPVYTKEKIIEIHEATKHLDTPIFLGVMPLTSIRSADFLHNEVPGI
KLSEEALDRMRACGEDKEKSTAEGIQIAKELIDTAAELFNGIYLITPFVRYDMTVELIRH
IRQLDLKKASDRAYA
>S7JGA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio fluvialis PG41|TrEMBL
MGYTHASHIDALNQNIADLSDINVSFEFFPPSTPQMEETLWNSVHRLKTLKPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDASREELIQIADDYWNNGIQNIVALRGDI
PPGGGKPDMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFDG
LDDDPVTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPSL
>A0A838CK13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium wankanglinii|TrEMBL
MFEASPSTRVSASAPLDREGAPLIRRPRSKRQRTALSFEIIPPRPTDDAAKLDQLIAGLA
EYNPDYVSVTSSRRSEWLEGTAGVISRIAETTDLRTIAHLACTAGTRDEMAEWVRVLMDA
GVRGFLALRGDLPETGLSADHLQYATDLLNLIQDVQEEEAFRLAAGKLALSVACYPKGHA
ESRNLDHDLDVLLTKQRLGADFAITQLFFEAQDYLEFVEVARLAGVRIPLIPGIMPMTSL
KRVRRMGELSGLEVPEGVEKQLLDAEDEYEAGMQLTANLAREILDAGTGGLHVYTHNNLA
VTRDFLDRIGIDKGQQ
>A0A1V9HGW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas phaseoli pv. dieffenbachiae|TrEMBL
MISTDTPHLASIVTDAYSLEVSIKDIGALTDAAPRILPGCAMFIPYLPGQNEAARLAAAR
TVRGLGFEPVPHLSARRIGALEELQASVARLVDEAGVTRCLVIAGDPATAKGPFPDSVSL
IETGVFERAGIRSVGVAGHPEGHSIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
LVVTWLEALRARGMSHPVRVGVPGPASVAVLARYAARCGVGACASVLSNHGISIGKLFGN
AGPDRFVGRLVSRLTQAHGDVRLHLFPFGGIAQSVEWVAQYRSRNAPQHRVSSGPADQA
>E8PJW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus (strain ATCC 700910 / SA-01)|TrEMBL
MKIRDLLKARKGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRERS
VLWAKRILGLKLNALAHLTVAGQSRKEVAEVLDRFVEAGVENILALRGDPPQGERVFRPH
PQGFRYAMELVAFIRSRYGEGVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRVGITIPILPGIMPITSYPQLRRFTEVCGASIPGPLLSKLERYQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNRSPATRRVLERLGFKPA
>C3XPI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Branchiostoma floridae|TrEMBL
MSSSGYTSSGASTPSNGSRPSSPTLGTPYVKLADRIEAKIDRGERWFSLEFFPPRTPQGA
ANLISRFERMVQGGPMFMDITWHPAGDPGNSDKETSSMSIACAALNYVGHETMLHMSCCN
STKDDIRRHLDKAKELGIRNILALRGDPIVGDEWKYVEDGFNYATDMVKFIRAEFGDYFT
VCVAGYPHGHPDSPTYEEDLQHLKEKVDAGADFIITQLFFKAERYVKFVEDCRRIGINVP
IIPGVMPIQGYHSLRNLVKLSKLEIPDEIREAIEPIRDNDEAIRNYGVHQAVTMIRELFD
SGLVNGLHFYTLNREVATIQILKQIGLWTEDIQRPWPWKRTANYNRCEEEVRPIFWASRP
KSYVYRTQEWDEFPNGRWGSSESPAFGELNDYYLFYLKPNAKKEELLDMWGHELTCLQDV
CDVFTNYITGKESKNGKKVRKIPWNDDDLAAETSFINDKLARINSRGVLTINSQPNVNAA
PSTDPVVGWGTPGGYVFQKAYLEFFTSRENVQALFKVLPKYPNVNYHIIKFEGDDDYTNC
DQQQPIAVTWGVFPGKEIIQPTVVDPVSFKFWKDEAFTLWTEYWGQLYAEDSKSRELIQH
IHDTWYLVNLVDNDFPRDNILFTVIEDMFAEADLQRAKGKGQTNGVNGVHHDDDDGVFVN
GAGDVPKNTCAEQIQRNVEADIVHAL
>A0A1V3IH09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter mrazii|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMENMLWESIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKKIAQDYWDSGIRRIVALRGDEP
KGYDKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHIIT
QFFFDIDSYLRFRDRCAAIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPNWLAKAYEGL
DEDPTTRNLVAASVAMDMVKILSSEGVNDFHFYTLNRSELTYAICHMLGVRPSV
>A0A1C5LVM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MDLSTLFRVKKVVFSLEVFPPKKDNPVHVIYNTLLGLRGLPADFISVTYGAGGSAVQQSK
TCEIASLIRSNYHIEPVSHLTCVNARKDKIIETLNTLKENGVQNILALRGDLPAGEENRS
DFAHASDLAAFIKSYDASFNLVGACYPECHYESQSLEADIENLKYKIDSGVTHLITQLFF
DNQRFYEFINKVRQAGITVPIQAGIMPIVNKNQIERTISMCGASIPTKLATIINRYSDNP
AALRDAGLFYATEQIMDLLENGVQGIHLYTMNNVQTATRISTAVESIIAAKNSANEA
>A0A6C1BQF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenobacter sp. T-8|TrEMBL
MKIGDYLRQGKFSVSFEFFPPKTSEGEEELFQTIKSLQQLNPTFVSVTYGAGGSTRDRTR
RVVERIHKETNLTVMAHLTCIAHTKEDLYEILKGYAQIGIENILALRGDIPANMPDFKPP
EGACKHGSELVRFIRENFGKTFSIGVASYPEGHPESPNMEWEIRYFKQKVEAGADFSITQ
MFFDNSYFYRFLELCQRAGIDIPIIPGVMPITNFRQIQKFASMCGAEIPQNLVERLEPYA
EDPEETLRIGVDFAIEQCLDLLDNGVQGLHFYTLNKSKATLLVYEGIKGALKT
>A0A7L6AXV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thiothrix singaporensis|TrEMBL
MNDAHEHEHESRDDLIFSFEFFPPKTDKGAENLRAVRTQLAELKPRFFSVTYGAGGSTQT
NTLNTVLEIQRDSGIEAAPHLSCVGSSEEQIREILQTYRGNGIRHIVALRGDLPSGTRDI
GEFRYANELVEFIRQETGDHFNIEVAAYPEMHPQAPNLKTDIDNFVRKVKAGANSAITQY
FYNADAYWHFVDACTAKGVDIPIVPGIMPITNYTQLARFSDMCGAEIPRWLRKQLETYGD
NAEAITDFGTEFVTLLCENLLETGAPGLHFYTMNRVEPSMGIWRNLGLSD
>A0A1V5DNS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophus sp. PtaU1.Bin208|TrEMBL
MSVLQNILFRMAETPLIFDGAMGTMIYDKGVFIQTCYDDLCLTSPGLIREIHEQYAQAGA
EVLETNSFGANRIKLRSFGLAEKVADINRAAVRLARQAAGQKLYVAGSVGPCTQGGQVIA
GPEIADVEAAFREQMEALTGEGVDLLLLETFSDLKELQLAARIARENGAPVLASFAVDEE
GETAAGTPAEKMAAALETDPNVDVIGLNCGTGPAGIYEALLKILPQVSKPVVVMPNAGMP
RTVGGRTLYLANPEYFTEYAKKFIELGVRGVGGCCGVTPEHIATAARAVRGLSGVRKHIE
IVSREPSPTQVQSIPTAEKSRLASKMVSGQKVTSVEILPPRASDFSNMLAKVRRCHEAGI
DAINIPDGPRASARVSPMITALVILKEVGIEPVVHYCCRDRNLIGMQSDLLGGYAVGLAN
YLIITGDPPKLGNCPEATGVFDVDAIGLTRMIHNLNAGWDIGGSPVDPPTGILIGVGANP
CAVDMEREIDRYFQKIEAGAEFAITQPVFDAEALLRFLDRVEKYPKRIPVLAGVWPLLSY
RNAEFMNNEVPGVVVPQKILHRMAECSTGEESRRAGIEIARTICTEVHDRVAGFQVSAPL
NNVEIALAVLGKGDF
>A0A7Z3AJ51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ADAK18|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKSAGIQRIVALRGDLPSGMGMASGELRYANDL
VNFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A078MBW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metalysinibacillus saudimassiliensis|TrEMBL
MGLLEKLQTSIVVGDGAMGTMLYATGLASCHEELNLLQPALVEKIHNEYIAAGADVIQTN
TYGANAIKLARYGLAHKVTEINRAATHLAKKAADGNVYVLGTIGGIRDIRKTDVTLTEIL
QGVKTQATVFLTEGVDGLLLETYYDFDELVATLELLREMTTLPIIAQVSMHEVGVLQNGK
PLNEALAELERYGADVVGVNCRLGPFHTIQAFEQVDLPQHAFLSTYPNASLLDVEDGRIV
YESEYDYFGRAAATLCKQGVRLIGGCCGTTPKHIAAVKKHVASLTPINEKPKRQIAVDFV
REAEPRTVKPLHEKAKQERSIIVELDTPRHLEVEGFIKGSEQLYAAGADVVMMADNSLAS
PRISNIAMGAMIKEKGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKVGD
FPGATSVYDVTSFELIALIKQLNEGISFSGKPLRKKANFSVAAAFNPNVRVVARAVPRLE
KKIEHGADYFISQPVYTKEKIIETYEATKHLSVPIYIGIMPVTSYRSAEFLHHEVPGIKL
SDEVLTRMRDCGEDKERATQEGIAIAKELLDTAAKYFKGIYLITPFLRYDMTLQLIAHIK
EMDEAAKGVSING
>A0A081BU62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Vecturithrix granuli|TrEMBL
MTTRLNITQVLQQRIIVGDGAFGTQLYEKGIPLSVCYDHLNITQPEIVIQLHQEYLDVGA
ELLETNTFGANRWKLQQYNLADSVRAINRRGAELALQCAQGAAWVAGSIGPLGRMEQEMI
SDDQKAEIFSEQAQGLLEGGVDLFILETFSSLADLLIALKAVKALQNIPTIAQLVFTDSG
KTIDGESALGAFFKLKQAGADIVGANCGIGPNGILKVLKNTAIKIDLPISAFPNAGFPER
RDDRMMYLASTEYLTETAVELVKAGVNLIGGCCGIGPAAIKAIKNAVSGLQSALKQPIDP
AAFVEIAAPPAFQEQIVSQSHLRVLLTRRKVISVELDPPKTLHIVNTLEGARILKQTGAD
VISIAENPLAVTRLSNVALARIIQKEVGIETIVHLTGRDRNLIGMQSELMGMAIEGIHNI
LAVTGDPPSRGKEERVKGVFDLRSYELISLLQRFNQGQNVDGDDLKAQTMFTIGAAFNPN
TQNMAIQVKRMREKIERGAQFFQTQPVYSKEKVDQLLELTHDLSIPIFLGILPLVSSRNA
EFLHNEFPGISIPADIREKMRNAGEHGIEQGIELAWELIEYAYPSFAGIYIMPPFNKYQI
AVELIKRIRRRFGVE
>G7LS48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brenneria sp. EniD312|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASRDHLREIAQDYWRSGIRHIVALRGD
LPAGGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRVPNWMTAMFD
GLDNDPETRKMVGAAIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAVV
>A0A0Q9ILU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. Root483D1|TrEMBL
MNAFRPSRHGSRRPRVSFEFFPPKNEDMEVSLWESVRRLEPLGPAFVSVTYGAGGSTRER
THNTVKRMIDETGLKPAAHLTCVSASCAEVDDVIRSYWAAGVRHIVALRGDPAGGLGTTY
EPHSEGYHQTSDLVEGIRKIGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRSRGIEIPILPGIVPVQNFKQTAGFARRTGASVPQWLADRFEGL
EDDPATRRLVAAAVCAEQVLDLIDRGVSDLHFYTMNKADLVYAICHLVGLKPEKAQAQQV
AAE
>A0A2N5IVR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium parmae|TrEMBL
MHQPMFSLEVFPPKRDAPVGTIYDTLDGLQGMHPDFISVTYGHGTHADRTATARIANTVR
KEYRIPTVAHLTALYSDEAKVDEALEMFEHAGVDAVLALRGDYIEGETPVGVFEHAIDLV
RYIRARKPDLKVFGACYPEGHYQAASLDDDIRHLKEKVDAGATHLISQLFYDNEDFYRFL
DKARAAGIDVPIEAGIMPINGAKSLRSMAAKNNTVVPPAVEALLEKWGSDVPTLREAGIN
YASAQITDLVAHGVDGVHLYTMNRPATTRRIWRNVRPLFTKTEE
>R7K2S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:277|TrEMBL
MKISDIYSEKKSLSFEIFPPKKTEDLENIDETLAVLCECDPDFISVTFGAGGSSNCNRTI
ELAKKIKNQYHVEPVVHLTCLHYDKKEIDEFARVLTEEGIQNVLALRGDRNPDIPEKEDF
KHASDLIRYLKPKEDFCLLGACYPECHPESENKIREMRHLREKVDAGAEVLLSQLFFDNE
QFFKFVEDCRIAGIQVPIIPGIMPVINARQIKRMVTMCGASFPERFQRIIHKYEDNKEAL
FDAGMSYALSQIIDLLVSDIDGIHLYTMNNPLVARRICDGIRNII
>A0A0D2EJM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala xenobiotica|TrEMBL
MHISKKLALAHEQNRPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRNS
QLTCEMVNAAQTHYGLETCMHLTCTDMEKLQIDQALRLAYKAGCSNILALRGDPPRDKEK
WEAKDEGFKHAKDLVKYIKTGYGDAFDIGVAGYAEGCDDNRDVDVLIDHLKEKVDAGASF
VITQMFYDVDIFLDWVKKCRDRGINVPIIPGIMPISTYASFIRRAEWTKCNVPSEWYKAL
EPVKNDDAAVRGVGKDLIVQMCRKLLDAGILHLHFYTMNLAQATRMILEELSLTPETSGM
PLEKPLPWRQSLGLNRRDESVRPIFWRNRNTSYIARTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNESNIKLWNKPKTLREVTELFVRFLNGQLDRLPWSEGSISAEANIIKEDLL
KLNKRGLLTINSQPAVDGAASDDPVHGWGPPGGWVYQKAYLELLVFPSMIETVIERLNAN
KNLTYYAVNNQGKLLTNAKDEGPNAVTWGIFPNREVVQPTIVETVSFLAWKDEAFRLGED
WAKCYPAGSGTRKLIEAIMAECYLVNIVNNDFHQTSEIFEVFEGLEANDLDKVFTDEPAD
SHTNGTRNVVSGDAPVSEIEQSLTSGEQRRVPFQTNGTALAG
>A0A1Q8D6P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. YN13HZO-058|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A3E1P9E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga silvisoli|TrEMBL
MKGTLQHKITAGKSGIVFYSLTPPKITTESEKVAVIANNQIERLQHLDIDGLILYDIQDE
ALRTEKERPFSFIPTISPEVYSKDLLTNLRVPKIIYKSIANHTKEMFADWLSQNTDLEAT
VFIGASSQQQVQATNFSLSDAYQVKKEMGPDILLGGVTIPERHTRKGDEHLRMFSKMQNG
CNFFVSQCIYNINETKNVMSDYHYHALSNDTQPVPVIFTLTPCGSLKTLQFMEWLGIEVP
KWVYNDLKYSKDILQSSIHTATNIAGEILNYATAKNLPVGFNIESVSNKKDEILAAHEIL
ENVLHMVKPLKNAVVEEKKAVSAY
>A0A2C9EUY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas protegens (strain DSM 19095 / LMG 27888 / CFBP 6595 / CHA0)|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAGYNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLQQYQAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEEDLVNFVRKANAGADSAITQYFFNADSYFY
FVERVRKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQVISDMCERLLQGGAPGLHFYTLNQADPSLAIWNNLQLPR
>A0A850YJ09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aegithalos caudatus|TrEMBL
MVNETQQTCSASSSSRSEGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTASAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKRYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A3M6Q0P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Franklinella schreckenbergeri|TrEMBL
MPAPTPALPLSLEFFPPKTEAGALKLRQARQQLYALAPQFCSVTYGAGGSTQAGTFATVG
EILAEGQDAASHFSCIGAHAAKLRAELQELRDMGVKRLVALRGDLPSGYGISSGQAEQRF
QYASDLVAFVREETGAHFHIEVAAYPEMHPQAASPQKDLQAFAAKVRAGADSAITQYFFN
ADAYFRFVDEARALGVDVPIVPGIMPIMGASQLLRFSDACGAEVPRWIRTRLQALGDDVD
GIRAFGLDAVTALCERLIAGGAPGLHFYTMNQSPLVLEVAQRLGLHPSAPAAPTMPAA
>A0A1G3UW41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp. RIFOXYD2_FULL_37_8|TrEMBL
MFDELINKLKNDTYITLETTPGHSPIFSPIIETIAELGLDKLVDGFTTTDNPLAKLKYNS
LFAAKMLQDRFHKPVIATMSMRDRNKIALQSDLLGANEVDVRAVLALTGDPATISDQPHT
KGVFEADSTLLLDIISCFNSGIDYAGKPFTCKPREIYPFAVINSYAKNPKTLQKKMQKKI
KHGAVGIITQPIYDIQSAKLLLDLKESTEHSSSAELIFGIFPITKLRTAQFLSAHVPGIN
VPNYWIEALRVANEKGAQEEYRVGFELSKKLFEDLKTLHPKIHLMTANQFQIAKDILI
>A0A255UDB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. P4-51|TrEMBL
MKVVELINIHKDKKNFSFEVLPPLKGTGTGKLFATIDKLKEFDPLYINITTHHSEYMYRE
LDNGQFERMRIRRRPGTVAIAAAIQQKYGIPVIPHVICSGATIEHIEYELLDLQFLGIEN
LLLLRGDKAKDDRVFTPVAGGHAHTTDLIEQVNRFNSGYFADGSAIKVPGTPFGYGVACY
PEKHDEAPNMEMDMGYLKMKQDMGAEYAVTQLFYDNSKYFDYVDKARAMGITIPIIPGIK
PLAKLSQLTVVPKTFHCDLPQELAAEVKRCKTDDDAKQLGIEWATHQCQELYAHGINNIH
FYTVSAVDSVAEVTRRLI
>A0A1I5MJS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sp. YR627|TrEMBL
MGHTLADKIKSGHSRLVFYSLTPPKITTNQDRIAEIAQAQAERISALDIDGLILYDIQDE
ATRTEQERTFAFIPTVLPEQYSRDYFHQLKVPRIIYKSIANLNAAQFQQWLTDNTDIQHS
VFVGASSQQQIEQTNFSLLDAYALRQQYAPSLVIGGVTIPERHAKKGDEHIRLTSKMEQG
CSFFVSQCVYNVNDTKDVLADYYYHSRETSQTPAPIVFTLAPCGSLKTLQFMEWLGIKVP
KWLYNDLKHSKDILQASIDTCLNVASELLEYADKKNMSIGFNIESISIKKDEISASIDLL
DQVLKLSKQSFKMAPERSLGKVVEEVRMPHY
>A0A3S2IE21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.002.06.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A436LNN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.002.06.1.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A1H2XXU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium degerlachei|TrEMBL
MKVTQHIEDAKGETLFSFEIIPPQKGKSIQELYDNIDPLMDFKPPFIDVTTSREEFIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGINN
VMALRGDAMKDEQSFVAKVGGNNFAVDLVQQINLLNEGKYLHDVMHVDNKADFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNSKYFEFVAKAREMGITVPIIPGIK
PLAVQRHLQILPQIFRIDLPEDLIDAVDKCKTNADVKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A0N8K6T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibaca calidilacus|TrEMBL
MSAPRISFEFFPPKTLEASFKLWDTVRMLAPLGPQFVSVTYGAGGTTRQLTHEAVTTIGA
QFDLNVAAHLTCVDATRADTLAIADSYAQAGVTEIVALRGDPPKGQGGFTAHPEGFANSI
ELIEALAATGNFNLRVGAYPEPHPEAADSLADVRWLKRKFEAGAHSAITQFFFEAETFLR
FRDACAAEGIDRPIIPGIVPIENWSGIRKFALATGATVPAWLDEAFEKAKRDGREDLLAT
ALCTELCDTLMREGVEDLHFYTLNRPHLTRDVCHALGVQPQFALENVA
>A0A6B3BLG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID9727|TrEMBL
MALGTPSTRTDHARTVREMLATGETSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATQDIAAESTLTPVAHLTAVDHSVAELRNMVGQFADAGIRNILALR
GDPPGDPMGPWVEHPQGVKYAADLVRLIKEAGDFCVGVAAFPERHPRSDDWDTDVRHFVD
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCDTPIIPEVMPVTNVRQLERLSQLSDAAL
PDDLKERILAAKDDAAAVRSIGIDFATRFSAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A1X2IZW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Absidia repens|TrEMBL
MKVIDKINTAEKEGRLFWSFEYFPPKTAQGVQNLYDRMERMQRMGPEFIDVTWGAGGTSA
ELTTEIVSTAQSVYGLETMMHLTCTNMPVEKIDNALKAAKQCGCQNILALRGDPPKGQSN
WESCQNGFEHAVDLIKYIRKQYGDYFCIGVAGHPEGHPDCPDKEQDLLHLKEKVDAGADV
IVTQLFFDVDAFLDFVKRARAIGITCPILPGVFPIQNYTGLKRVISFNNNFVPQKIWDDL
EPLKDDDAAVKEYGINLTIDFIHKFQQAGIKGFHIYTFNLERSTRLILEQLNLVAPMEAV
KPLPWLPALTQKRAKENVRPIFWKNRTKSYLQRTEFWDEFPNGRWGDSRSPAFGELDGWG
VSLKYSQEQCQDMWGQPETVDDIAVVFAKYCKGKIAGIPWSAQPLEAETETIRQRLAGIN
LLGYLSINSQPAVNGVKSSHPTYGWGPKNGYVYQKAYLEFFVSPEKLDDLIKKIGKDPNV
TYYAVNKQGDLRANTQSDHPNAVTWGVFPGKEVVQPTIVESTAFMAWKDEAFELWNEWAR
IYDRKSKSADLILDITNNWYLINIVHNDFQDEGGIWRLFDLEIDGEISRKIRQNGGDDY
>A0A1G5ZH64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. NFACC15-1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGEHFHVEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A127VJJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter cryoconitis|TrEMBL
MKITDHVTNAKGKTLFSFELLPPVKGKSITDIYDAIDPLMEFNPPFIDVTYHREDYIYKQ
HDNGLLEKVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADSTFIPTPGGHAYATDLLGQVNDMNNGKYLFEDHSAFQTDFCIGVAGYP
EKHFEAPNLKADFKYLKQKVDMGAEFIVTQMFFDNAKYCDFVAQCRANGINVPIIPGLKP
ITSSKQLISLPKIFHIDLPEDLTEAIQECKNEKDVKEVGIEWMIQQCKELIKVGAPVLHF
YTMSNPEPTKRIARAVF
>A0A428NNE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sp. AF-6|TrEMBL
MDRITDRIAALPADGSYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRREE
YRDPDDSEDDGGQDFNWAADLVKYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVEAGADFIMTQLFFDIKAYEHFENTLRDHPSGAFKTLPIIPGLMPIQSYQMIKRT
TKLSHAQIPEDILARLNAVKGDDEKVKMVGVDIVSELVEKVKDIKSKTPGPKGFHFYTLN
LEKAVSFILERTNLIPEPPEDEEALVVDDAIPIPALQVNGSSNLRSGSHSRSQASRRHSS
VGSDPHNRVIVGDRPATHPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDF
PNGRFGDARSPAYGEIDGYGVSLHMSITQAVKFWGHPKTRQDINDLFVKHIQGELSAIPW
SEEELLAESSTIQPHLLRLNQKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEF
FIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVSSDKGGHVDGSSEAGPSTNAVTWGV
FPGKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSDSEKLLSGIKDEYWLVNLIHH
DFVEKDALWQVLSS
>A0A1Q2TKE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. Chiba101|TrEMBL
MSTTPDDSAPAPHGAPTLSLELFPPRAGAAASQTWSALDRLLATAPDFVSVTYRPTFVLG
TRPAEPAVRVIREHNPAEDVVTHVLARSSTPLMAHLTCIGYRKRDVVEIVRLFLALGVRR
FLALRGDPPRGHDADELPGELAHAEDLVRVIREVEAEYFDDGERHLTIAVAAYPAVLDHG
RGVEILAAKQAAGADLAITQVFYDPEDYLSLARAATYCGVSMPLLPGILPMTDLARLSRL
AALTGVPIPAGLAASLGPARGAQTVARGIDATLRLATEVLDGGAPGIHLYTFNRTRPALD
VISQLRLGGILGGERVSASMQRDVRRAYLNATPGGDRRMPEPAHAGSARP
>A0A2S5XLH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. AY1F3|TrEMBL
MTRARFEIIPADDIGERAARAFPDPSAVTLTVTSLPKHGTERTVDCAVALAGRGFRVVPH
LAARNVEGRAALERVLGRMGEAGIDEAFVISGDASSAAGTYSTSLELIRDAREISPGLAL
DIAGYPEGHPHLSDESIERHLRERAPFIRSIVTQMCFDVDAVVRYADRLRETGITADLWA
GVPGPVERSRLLTLGARIGVGSSLGFLKRSTSVAGGLLRGRRFDPSAFVARLEAAAGDRL
AGLHVYTFNELDSLAAFG
>A0A8A0RL81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Koleobacter methoxysyntrophicus|TrEMBL
MSQLQKALENGEFAVTSELAPPKGTDFSHVLKCAELVRGRVCAINVTDFQSSALKATSLA
MCKALQDRGLEPVLQITGRDRNRIAIQGEMLSAGFFGIKNLLAITGDHTTIGDNPGAKPV
FDLDSVGILQAASTLMNGFDMGGNKLDRAPSFFLGATVTPEYDPIELQIVKMEKKVKAGA
RFFQTQAVFRIETMEKFKKLTEHLNVPVIAGIIPLRSAGMAKFMNKNIPGINIPDNIIDR
LRSSDNSVKEGIKIAGELIAELKEKGLCSGVHIMAIGAEENVPLVLDAAGV
>A0A1Q3ZYM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micrococcales bacterium 72-143|TrEMBL
MTGDAACPTFSFELFPPRDAQAETALVADTLPALVGAGPEFISVTYGASGTTRGVSLDVL
RRLLATPVKPMAHLTCVGSSYAEAGRLIREFLDAGVTSFLALRGDPPAGVSEDEAFLGDL
GSAGELVQLIHRVQKERVPFRQLDVPGVPGAKRLASGEKVTIAVAAFPNGHPRSRSRAQD
LDTLLAKEAAGANLAITQLFFEADDYLGFVDDARAAGVTMRILPGIMPVLSVPRLRRILD
LTGEREPTALLRELEASGDPASVGVAHAARLGRALLDGGAPGLHLYTFNRHEAPLAVLEG
VGLLPQPARIGEHSA
>A0A087FF66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 1-7|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFG
EQVITEMCERLLQDGAPGLHFYSMNLAGPSLAIWNNLKLSR
>A0A2L0A939|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. SCG-1|TrEMBL
MTFSLSQMEEARRALDVPLFADLSGDAQVSFEFFPPKSEKMEQQLWSSIETLAPLGPRFV
SVTYGAGGSTRERTHATVARIAKETGLSAAAHLTCVGASKDEIAEVADAYWQAGVRHIVA
LRGDPPEEGQAFVPHPHGYSSAADLVTGLKALHPFDISVAAYPETHPEASTSQSDLDNLK
RKIDAGASRAISQFFFSADAYFRFRDAAAAAGIDAEIVPGILPVSNVSQTRKFAAMCGAA
IPPWMDRLFEGLDDHPATRQLVSATIAAELCRKLYAGGERHFHFYTLNRAELSYAICHLL
GLRPTVAAKPKELVA
>A0A356HCF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp|TrEMBL
MTDRYFSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSTRDSIRTILQTYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQARSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRAMGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDKEAIRAFGLDV
VTDLCARLLDAGVPGLHFYTLNAAGATKAVWQRLKL
>A0A2G3EA86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio ruminis|TrEMBL
MFREMLSRDASMSFEVFPPKKNDEFDNCYNVLDSLAKLNPDFISVTYGAGGSRSKKTVEI
ASYIQNTLKIDAMAHMTCVGSSEDDILEVTKDLEASGVSHVLALRGDKPRDMSDEQFAKR
IFPHATDLIRFLNTNTNLDVSAACYPEKHPEAMSIDSDLAFMKMKQDMGAKMFISQLFFD
NADFYRFVERADKAEIHVPIVAGIMPITSAKQIGSTVTLAGSSVPKKLADICAKYGDFPE
DMRKAGIEYAIDQIRDLRKCGMGHIHLYCMNKPKMTEIICKSI
>D6CV62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomonas arsenitoxydans (strain DSM 22701 / CIP 110005 / 3As)|TrEMBL
MASAQSVSPRVNLSFEFFPPKTPEGADKLRAVRQRLYARQPEFCSVTFGAGGSTQEGTLQ
TVRDILAEGVDAAPHLSCIGASRDSVRGHLRDFQAAGVKRLVALRGDLPSGYGIGGEFHH
ARDLVAFIRDEMGSAFHIEVAAYPEMHPQAKSPLDDLQHFADKVRAGANSAITQYFYSAA
AYRRFVDDVRALGLDVPVVPGIMPITNSSQLLRFSEVCGAEIPRWIRLRLQSYGDDRESI
RAFGREVVSSLCEELIASGAPGLHFYTLNQAEATLAVLDDLGR
>A0A510KIZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia trevisanii|TrEMBL
MKIKDMFEQKEHLISFEIFPPNKNFSQEKLKEVTAELVECKPDFISVTYGAGGQTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEIHDYLQEAKSKNVKNILALRGDVPQGETENIYN
KGDYKYASELISDLRKNSDFDDFSIGGAFYPETHYENNDLVDLFHLKNKVEAGTDFLTSQ
MFFDNDIFIKFKEQAEKLDIKVPLVAGIMPVTNAKQIKRIIELSKCSVPHKLDKLLEKYG
DNPESMKKAGIMYASEQIIELLAYGIKGIHIYTMNKPEIAKEIMKNIEFAR
>A0A3M0XZR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Parcubacteria bacterium|TrEMBL
MNERPLRANSRLERVLRSGRFAVTAELNAPDSADPEDVYKNALVLAEVCDAINATDGSGA
NCHMSSLGCCALLTRAGYEPVLQVSCRDRNRIAIQGDL
>A0A3G9JE16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis viridis NIES-102|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQEVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A510JYJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia trevisanii|TrEMBL
MRIKDMFEKKEHLISFEIFPPNKNFSEEKLKNVTAELAECKPDFISVTYGAGGKTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEIHDYLQEAKNHNIKNILALRGDVPQGETEEIYN
KGDYKYASELISDLRKNSEFNDFSIGGAFYPETHYENNDLVDLFHLKNKVEAGTDFLASQ
MFFDNDVFVKFKEQAEKLDIKVPLVAGIMPVTNAKQIKRIIELSKCSVPHKLDKLLEKYG
DNPESMKKAGIMYASEQIIELLAYGIKGIHIYTMNKPEIAKEIMKNIEFAR
>A0A2M8SSS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. WCS365|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDASSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A6L3ZIW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeocystidibacter marisrubri|TrEMBL
MRVDQHIKDAEARNETLFTFEILPPLKGQTIHDIYSNIDPLMEFKPPFINVTYHREQVVY
KRLPNGLLEQKVVRKRPGTVGICAALMNRYQVDPVPHLLCGGFDKEDTENALIDLHFLGV
ENVLALRGDGMQDQVYFVPETDGHAYASELVEQIVNMNQGIYLDDELINNSATNFSIGVA
GYPEKHFEAPSLNVDVSNLKRKVDAGANYIVTQLFFDNSKYFEFVDKCRAAGITIPIIPG
LKPIATKKQLSMLPHRFHVDLPDELALEVMKANDNAAVRQIGVEWAIKQAGELKAAGIPV
IHFYSMGKSDNIYNIAKELF
>A0A7X9HAH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVSERIQTATKTAFSFELLPPIKGNGIYQVFDTIDKLKEFDPKYINITTHHSETVYKED
ENGVIRKVNIRRRPGTVALAAAIQNRYGITAVPHIICKGFSKQETEYALIDLMFLGITNL
LLLRGDTNKLNEEQIKMDSHDHATDLQEQVNNFNKGIALDGSRFTPPEEPFSYGMACYPE
KHAESPNMDSEIFYTKMKVDNGAEYLVTQMFFDNRKYFDFVDRCRAEGILVPIIPGIKPV
HLKNQLTVLPKVFGTNIPEDLAKELRKCKNDEDAKEVGIEWCIAQCKELIQHNVPSIHFY
SFMATDSVYQVAKEIY
>A0A0V1PDY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella sp. T8|TrEMBL
LASILKKILFLSLMASLEAVELKATRHDLNSAAKKSTDEIYRPLIDRIKENISNGRRFFS
LEFFPPHTTEGLINLLKRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCILNFCL
LDTMLHITSVQYDEKTVLFNLERAKKIGIRNILALRGDISDDANVTTTDFQYACQLVRFI
RSHYGDYFTICVAEDLLNLKAKVDAGADFIITQLFFNEMHYFKFVSDCRKIGIVVPIIPG
ILPIQSYQSIMKIVQLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRKLLNREHH
VVPGLHFYTLNQEKSILEQIGFWKKAPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYL
CRTRDWKQFPHSRWSDVGNPAFGDLKHYLFSCIDQMDDSCALDMWDKELSTLEHVRDIFC
NFIARTPNRHGHSVRRLPWNENHLDPATDVLKNELIYYNSNGILTINCQAAVNGLPSSDP
IFGWGEANGYIYQKVNARCILISLGYLEFFASSTCTTILLNHVQNFPSINYHAINFDGSF
ETFNYDEDATVALTWGVFMGQEIVQPTVANAASFRVWKVVAQLSFIQSFLFVFEQDEAFD
LWQRWAGLYESGSIGRKLLQRIHDDYRLITLIDNDYPQPCSLSALLRAVISDYIGGKNLT
TDDDRLACRLALRASKHGITAEKEEEEEAIIE
>A0A829KCV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii EGD-HP18|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSVNIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIGAL
KQAKSFLTKHNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQAGHTDR
IYLRCALQILICKHLGFAGIHLSACHKPEEQVLLESYIEQYRHLNLKALEELWSSLWQVK
TGKEFSPEITHFSCQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILREKLIPTVPLETRGTSSWKNWYLATEA
>A0A7X6PCU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
CPKGLRNGPCGGITPEKNCYIDETRKCIWYAIYSRALKTGREERLLEVLPPLDWNKTGTE
TWGDVIRQVRKVGTLNFIRGNLSSDKEKRKNTWESVFRPVRQPSWWQGDSEYHPPVLSEP
VSRFEKKLRRGEFVLTTEVSPPLGANPAQLVRKIELVRPYVTAVNFTDSSSANPRMSSLA
CSAVAADLDAEAVLQITARDTTRTGLQAMATGAGRFGVKNILCITGDSPKVGPSPAASLN
FIDIDSVQMLWILRKMRDEGTYLDGRRTKYPPEYFLGAATTPFASDPVLQAIKDQKKVNA
GAQFLQTNIVFDPGRLDLWLEQLDKRNVLDKIFILVGIATVKNYRTARYLHDHVPGVFFP
GRILSRMEKAGDGEAEEGVQIALEIISSLKGKKGINGIHIMTLGWEEAVERIVKDSGL
>A0A8F9U4K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. 7D3|TrEMBL
MGLLQDLEERILIGDGAMGTLLYSYGIDRCFEELNVSKPDEIKRIHKAYVEAGADIVQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTS
LREALKSIAGLGADITGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEGGRLVY
DTDDAYFRESAIQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTDKEVKIRREEEVI
SVRDERTEPGLDEIAAQKRSIIVELDPPKKLNFEKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGALLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLTTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMAQAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A149TVU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter senegalensis|TrEMBL
MSLSRLSVELIPRSTEALLDDVASVKALFAAADTLNVPDLMRFPLRSWDAAALIRPHFAR
VVPHIRAIDIAPDAPLPGADQPGLEEVLVVHGDPPADLSHRTYPNSTESIIRRYKKEAPH
LRIYAAFDPYRRAPWQELEDVARKKEAGAEGFFTQPVFDLKLFDLCREWLRDETVFWGLS
PVIGPRSRSYWETTNHVVFPKDFEPTLEANIQFAQTVLRQLSQEKGRAYLMPLRVKLDQY
LPPLLEALA
>A0A4Y8HZ16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium MT.SAG.1|TrEMBL
MIHHIQNKIYHVELLPPKQDSEKLEKDLEIFSNKYLRVMDSGYYACIPDNAMGLLSFQGT
EMIEELELPVIPEQVMIHLNTFHTKDDLDNILDICKSKGIRYLLIITGDGSERLPKLQPS
DVGATDVESVTSVELLKYINCEYPDTFVLGVAFNPYEPEEHEFKKMERKIKAGATFIITQ
PLIERNEVVDGLLKKYPEILVIVEAWMSRKLHLLSEAVGYEIPENTEFDPISTLKMLHKL
YPECGIYLSLLGFKTQYDLIKDIWV
>K9DUZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides oleiciplenus YIT 12058|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAGAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIHWLKQKMEAGAEYAVTQLFYDNRKYFDFVERAQKAGVTIPIIPGIKP
FKKMSQISMIPKTFKVDLPEELAREAMKCKTDEEAKQVGIEWCVQQCKELVGHGVPSIHF
YSIGAVDSIKEVAKQVY
>A0A1E7GYZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium C00003106|TrEMBL
MKRSFKEALTSGKFLVTAEVASPKGIDADSLGPIVGNLKDTVDAIGVGDNPRGVMSMSPW
AACHLISESGGEPIMHLTCRDRNRMALQSDLLAAAFLGIRNVLCVTGDHVRFGDHIDAMP
VYDLDSVQLIETVRSLTGGRDMTGHELAGAPEFCVGAVANPESDPVGPQLFKFKKKLASG
IDFVLTHPVFNPDNLAPFVSEAKEKGVKVIAGVSLLVAEEIPGYKDGSHPGLFVPDEVLA
DIEGAGIEKGIEIAARLIGTIKDKGLCDGVHISAPGHEEKIIDIIKSSGI
>A0A315E0U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. 2KL-1|TrEMBL
MSGLKLPISLEFFPPKTPEGAEKLRGVRQALYGLKPEFCSVTYGAGGSTQEGTFATVGAI
LAEGVPAASHFSCIGATKASVRAELATLKAMGVQRLVALRGDLPSGYGAGGEFHYASDLV
AFIRAETGDDFHIEVAAYPEIHPQAKSPEADLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQAYGDDIASIKAFGL
DVVSDLCEQLINGGVPAIHFYTMNQSAATLEIAHRL
>A0A3B9T4U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVTEHIQKASKTLFSFELLPPLKGEQFSHIQDKINPLLEFNPAYINITYHQEEIEYETL
PGGLLKKHTVRKRPGTVGISSAIQYKTGIDVVPHLICGGFTREITENALIDLYFLGIDNL
LLLRGDPPATQKYFVPEPDGNAFAVDLVKQVSNLNKGIYLEEGLENAHPTNFCIGVAGYP
EKHPEAANPQSDLINLKAKVDAGADYIVTQMFFDNQKYFDFVKSCRAIGIDIPIIPGLKP
LSAKNQLVALPQTFHVDIPQGLAKEVQKCKSKQSIYELGIAWSIAQSKELIAAGVPVLHY
YTMGKSDNIRQIAKAVF
>A0A318L5P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. LBP4|TrEMBL
MDSLVNRLAPPTELVLEAVPPELGQGESGIEATLERIAGLHRVLGLDAVNIPEIHEERSR
SHKGERRRPFAPRVEPRLLARYIQERLDLPCIINRVVVHLEAERQLEWFRETWERYGVRR
FVLVGGERSDRTYPGPSVPEANRLLRERLDAPRMRIGNICIPTRRGEAERMQHKVAAGAD
FFTTQVIFHAEELTALLDVLGEPRHGRRPPGLLISLAPVRSARSIHFLHWLGVSLSDELE
TWLTRGPESVTERSLWHIHDTWARLAHHAAATGTASPLGINLAPIGAIPAATTIRLAQAL
RDGRVHRRGAASPSLP
>A0A353YYT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKITELFLSQERTFSFEFFPPKDEISAVDFGINVGQLMRLSPSFVTVTYGAGGSNQHKTF
DLVDYLQNRIGLTTVAHYTCVNASRNRIVEDLNHLQTINIENLMLLRGDPPKGEEKFIAP
KDGFKYASDLISFVDENYDFAKAGACYVEKHPEAHSFEEDLANLKTKVDAGADFLISQLF
FNNSYYFDFVRKARKTGINTRIIPGIIPITAYRQIERFTKMSGTKIPPELAVRLEEHKDN
PSKTYQIGVDYTIQQCRELLANGAPGIHFYTLNKSRAAVEIFESL
>I3S0L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lotus japonicus|TrEMBL
MKVIEKIHEAAASDPNKVVFSFEFFPPKTEGGVVNLLERMDRMVAHSPSFCDITWGAGGS
TADVTLDIAKKMQNTVGVETMMHLTCTNMPVEKIDDALETIKSNGLQNVLALRGDPPHGQ
DKFVQVEGGFACARDLVKHIRAKHGDYFGITIAGYPEAHPDAIGSNGLATPEDYQNDLTY
LKSKVDAGADLIITQLFYDTDIFLKFANDCRQIGITCPIVPGIMPINNYKGFIRMTGFCK
TKIPAEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGFKTLHLYTLNLEKSALAILK
NLGLIEETSIPRTRPANAIQAKEDGENQERPTEDMVVQMA
>A0A7X6JC76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium R_SAG10|TrEMBL
MPAARISFEFFPPKSLQASFRLWETVRTLAPLEPEFVSVTYGAGGATRKLTHEAVTTIQK
NYRLNVAAHLTCVDATRAQTLAIALTYAGAGVRDIVALRGDPPAGQAAFRAHPDGFSNTC
ELIEALARTGNFNIRVAAYPDRHPNAANDHADVDWLKRKIDAGASSAITQFFFEAETFFR
FRDRCQAAGITAPIIPGILPIENWNGVTAFARRCAAPVPPWLDQAFTAALRDDRHDLLAI
SVCTELCSYLIEGGVEDLHFYTLNKPSLTREVINALGLAPDTAIKKVA
>A0A842Y895|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MPEVSSRYFLSESILSYWYIKSKLRSGFFSDSYTNSECCNLFDTRLKQTLDAGIFAITGE
IGSPRGADHKLVIERTKLIADYCDAINITDNARGIPTMSSTACAHIVLEAGAEPIMQLST
RDRNRISIESELYGVYALGIRNILFITGDRMIVGSHSEAKMVFDIDSIQALQLSSHLMQG
MNLDGEELEGTPQFFMGSTFNPYADSIETEIHRAEKKRDAGASFFQTQAIFDTDRLESFM
DLARDLELKVLAGVIPLRGPKNARFMNANVPGIEIPEEYVRRLETAGKGLKEDAERNALR
EEGLLIELEIIKSIRKIKGIDGLHFMGKGWE
>A0A524ELR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MELSDMTKSHLRTILNSGDFVVSGEITPPHGSDKNLLLERLSLVKGYCDAINVTDNVRGI
PTLSSLVATYLIKQTGQEPVMQMSARDRNRILFESELYGAHALEIPNVLFVTGDHSTLGS
HPQTKMVYDVDSIQALALAKHLMTGHDFAGDELEGTPQFYLGSTFNPYADPMEMQVLRTH
KKQEAGAEFFQTQAIFDPGRFRDFIKELGTIKAKILGGIIPLKGPRMARFMNRRIPGIKI
PESMIERLEQAGEGLKGKEKIKSVRGEGLSIALETIEAIKKTQGVDGIHIMGIGWEESIP
ELVERSDLYPRPRGD
>A0A368TTP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas montanilacus|TrEMBL
MKFEDEPVPGYSLPILPGHVSPGRLERVLRAGKFAITSEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGANCHMSSAGVCSLLTRVGYATILQISCRDRNRIAMQGEILGGAAMGAC
NLLCLTGDGVQAGDHPQAKPVFDLDSISLLQIARGMRDEQRFESGRRIETPPRIFLGAAE
NPFVPPLDWRPLRLAKKVAAGAQFIQTQYCFDIERLRDFMLKVNDLGLLEGPDRVFILPG
IGPLASARSARWIREHVPGVHIPDAVIARLEGAENQKEEGKRLCMDLLHEIREIPGVSGA
HIMAYRQEHSVAEIIETTGVLEGRVPWYPGRDDPKALNPESPDALQL
>A0A6J2K9T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bombyx mandarina|TrEMBL
MSSERKKITDLINIPGFTFSFELTPNISEDEINALEMSPVFFSVTWHAKAHQCKNLEIDP
LQTVRLLKSKGKNVLLHLTCDLLRMSYLDQLLIFLKEQDICNLFVILGDNYNPDTSDFKS
TTELIKYIREKTGDYFCIGIAGFPDCSDEKLLQLKQKLENGADFIVTQAFFEPEILKKFI
EQCENCGIKAPILPGVFLFENYDQLAKFLNMCKGKVSDNFVNIIKSKEQSGAPCSEVIKK
MVQDLKEQININHFHFFTMNKMQSVCNLIKQLG
>A0A7J4T468|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poseidoniaceae archaeon|TrEMBL
MDVASLYRNAPGGLPFSLEILPPNRGLGLNNIHDFFNNLHEWLPAFVSVTYHQAHKIDII
DDNGQMEQIWNRKKPGTLGVCAMLKFQYGLNVIPHVICGGFSKFESEDFLVDLDYLGLKH
ILALRGDPNKTETQFNPHPQGYAYANELVEQIVDMNAGKYVEDVKEARPTDFQIGVAGYP
EVHAEAMNLHDDVTNLKRKITSGASFVITQMFFDNTCFFQFDKMCREMDIHVPLIPGIKV
ITSKRQLEVLPEIFGTKLPKKLVDDVMACETDEEVCQVGIAHAVNQTKELLEYGVVGVHF
FTMNNSQVFNQVLQQFQE
>A0A0L0C973|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lucilia cuprina|TrEMBL
MTSLVLKVHRDYQQLKLILIKFATIKMSTTNNNQLINQTVVTAMGAHILPSISHSSYDLK
LQFNENGSATPDQQLKFEIEKKVKNKEFFYGIEILARNHHANTLLDYKAFGSIMPLFTSI
VWLSSDYWAVENIEEVESIKLARKLQPHGIVLPHFSCYRLQEPRLKEFLNLNFSNVLAIR
GDFFEPNQSYKYSEELVANIRKLKGVSIIIGVVWYPESHYGFRSLEDDLNNLAKKVQVGA
DFIITQICFSPQAIIDFVKNCRSKAINVPILVGIFVPDNLRMLEAILRITKIKMPAAELE
EYRQQNELGHINFRDYAVNKAVQMIEAIFASDADVYGLQFFTMNKFKNIPKVLSALEKNK
NLIKKR
>A0A4D9C1T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salvia splendens|TrEMBL
MKVIEKIQAAASANDDRVVFSFEFFPPKTEDGVENLFDKMERMVAHNPAFCDITWGAGGS
TADLTLEIVKRMQNMVCVESMMHLTCTNMPVEKIDHALTTIKSNGIQNVLALRGDPPHGQ
DKFVQVEGGFACALDLVKHMRAQYGDYFGITVAGYPEGHPDIIENGLAPEAAYQSDLAYL
KKKVDAGADVIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPSEVMEALEPIKDNEEAVRAYGIHLGTEMCKKILASGIRTLHLYTLNMEKSALAILVF
MRPRSRDKKLQEEWAVPLKSVEDIYEKFMSFCLGKLRSSPWSELDGLQPETKIINENLGN
INLKGFLTINSQPAVNGAKSDSPTVGWGGPRGYVYQKAYVEFFCSPERFTALVEKCKQFP
SLTYLAVNKEGTLKSNVSNNDVNAVTWGVFPAKEIIQPTVVDPASFVVWKDEAFEIWSRV
WANLYPEADPSRKVIEEVKCSYYLVSLVDNDYVHGDLFAVFNSI
>A0A1W6L456|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobacter gummiphilus|TrEMBL
MSQPFPISLEFFPAKTPDGVTKYAAVRQELYALKPAFCSVTAGAGGSTHRGTLDMVRDIF
TEGFEGAPHFTCVGASKASVVEALGQFREAGIRRIVALRGDLPSGYGSHGELRYASDLVE
LIRAETGDHFHVEVAAYPETHPQAKSPQADLQAYAAKVKAGANSSITQLFFNADAYFRFV
DDARALGADVPVVPGIMPITNASGLIRFADNTGAEIPRWIRLRLQAFGDDVESIKAFGLD
VVSDLCERLKAGGAPGLHLYTMNASAASLALAKRLGL
>A0A286UW93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrrhoderma noxium|TrEMBL
MKLSEKIAAYDSPNPFFTLEFFPPRTDQGFANLLTRISRMSTLDPIAVSVTWGAGGSTKE
RSLDLAEITQTEYGIDTILHLTCTNMEQGLVDDALRKAKERGIVNILALRGDPPRGEEYW
IPIDPRFAHAIDLVRYIKSSPEFSDSFCVGVAAYPDGHTDSDFDEETELEHLKAKVDAGA
DYIITQLFYDVDGFLVWLKKVRSKGITVPVIPGIMPLQSYASFQRLTKLCGTKVPTQLLL
DLEPFKNDDQKVKDFGVSLATNMIQRLTSEGDIKGVHFCTLNLERSVRLVLESLQWTGNS
LETANKLITDPQDTSGNFTINPADAFQTATDKLATKPLPDIQEPGKGEVNNASTWDEFPN
GRFGDYKSPAFGLQSDPWNSGVGNSLAISRAEAISRWGSPRNASDLTDLFLAHLYSKVTS
TPFSPTPLSPESLLILPHLEKLTRRGWWTVFSQPAVDGVDSADEVFGWGPLGGYVFQKGF
VEFFAEKEDVEMLERRIESNGRGWVDFFAANEEGELRTNVPDGGRNAVTWGVFPGQEIAQ
STIIERDSFLSWKDEAFSIWEQWSSFYAPGSEERTYLESVRKERWLVSIVHHDYKDSSRL
WSFILDD
>A0A077NTP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus bovienii str. feltiae Moldova|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPSTTTMEQTLWKSIERLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKDKTGLDAAPHLTCIDANREELRNIAHDYWESGIRHIVALRGD
LPDSSGKPEMYGADLVQLLKKEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A2S7WBW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter gangjinensis|TrEMBL
MKVTDHIKNANGKTLFSFEIIPPKKGNSIQELYNNIDPLMEFRPPFIDVTTSREEYVYID
KGNGLLDRKITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFTKEETEYVLVDCHYLGIDN
VMALRGDAMSHQKYFEPIEGGHEYAKDLVAQIHDLNRGKYLHDVVEGNNKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGAHYIVTQMFFDNNKYFEFVEAAKKMGITVPIIPGIK
PLAVKRHLQLLPQVFRIDLPETLISEIEKCSTNQQVRQVGIEWAIQQSKELLAAGVPVLH
YYSMGKSDNIREIAKELF
>A0A4D9BEL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salvia splendens|TrEMBL
MNLGWLCEQFGCEDEGDRQDPERKRRDVLVRILPPPPPPPPPKYIRAKYGDYFGICVAGY
PEGHPEVIQENGVVTAEAYQKELVYLKQKVDPGGEVIITQLFYDTDIFLKFVNDCRQIGI
TCPIIPPEIMAALEPIKDNVKAYGVQLETDMCRKILASGTRAIHLYTLNMEKSALAILTN
LGLVEESKFPRSLAWRRPTNVFRAKESVRPIFWANRPKSYIGRSISWDRYPNGRWGDFQT
PSFAPLTDYQACTTTFLRPRSHEKRLLEEWVVPLKSIEDIYEKFAKFCLGKTKSSPWSEL
YGLQPETKVFNEQLGNINMKGFLTINSQPAVNGAKSDTLAKMMFVGTGWGEAGGCVYQKA
YLEFFCFPASLTALINKCKAFSCLSYMAVNREGAWISNMKNTDVNAVTWGVFPTKEIVQP
TIVDPLTFMVWKDEAFELWSRGWANLYLETDPSRKLLEEVKNSYYLVSLVDNDYFHGGLF
ALFRDT
>A0A7J9ZC17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangiales bacterium|TrEMBL
MAIETTTPLPTRHAKLGDMFAEGGASYSFEFFPPKTDKGEQNLFHAIRELERLQPSFVSV
TYGAGGGSRDRTVGVTQRIATDTTLTPLAHLTLVNHSVAELRQVIGQYADAGVRNVLALR
GDPPGNPQGEWVQHPEGYAYSADLVRLVRASGDYSVGVAAFPEKHPRSPDLETDARFLVG
KFEAGADFAITQMFFHVEDYLRLRDMVAALGCDKPIVPGIMPVTNVAQIEKFAILSNAVF
PEDLAARLHEVEDDVDAVRHIGVEYASDMCVRLMAEGVPGLHFITLNKSTATREIYERLD
LTPKPS
>A0A845DAV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineaceae bacterium SB0662_bin_25|TrEMBL
MTIPDQTPPATEWDSHGAESRLRQVLEAGHFAVTAELNAPDSADPKDVYANAAELGDVCD
GINATDGSGANCHMSSVACCALMARAGYEPVLQMGCRDRNRIAIQGDLLGAAALGVRNVL
CLTGDDVSAGDQPEARRVFDFDALHLLRTAQIMRDQGVLLSGRKLTTPPEFFLGAAANPF
VPPQDLRHLRLAKKIEAGAQFIQTQYCYDVPVFEAFMRRARDMGLHEKVYLLVGVGPLRS
ERAAEFMRSRVPGVHIPDAVVDRLAKTPRKGKREEGIRICVEIIEEVKQIEGVRGVHIMA
YRQEEAVPEIVERAGIKRERPRE
>A0A8J8D3E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula sp. R1-2|TrEMBL
MALGTRTVSDSQGVRTLLTSARFELMPFESFDEEISHLPDNATIAITTSPQLGIEKTVEK
TAEAAEMGYDVVPHIAARYVEDREQLESIAERLEQAGITDIFVPGGDREEPAGEYESALD
MLEALEETEYSFEEVGITGYPEGHDFIDDETLAESMAQKAPYATYIVTQLCYDPDAVLEW
VEDIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVEDDEYNIRGVHIYTFNQTPDTEKWRHKRLDS
>A0A2M6ZKL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG07_land_8_20_14_0_80_60_11|TrEMBL
MPLQEKLTSGEFVILAEMEPPKGTDVSDMVGAATGVKRMVDAFVVPEMNNAVMRLSSLGG
ALLLQSRGLETVMQVCCRDRNRLALQGDLLAAQALGVSNVMAVAGDEITHGDHHQAKAVN
DLNLLELLAAIQTLQTGRDLAGVDLKGAPQFLVGATVKVTNDAFALKQELANLDQKIAAG
ARFFTTQPVFDVEALEKFRRQLGERQAAIIPTVMLLKSVGMARYINAHMEMKIPEVLVTR
IQKSSDRVRECVQIASEFVAAVKKQGFPGVLVSTIGWEDKLPSILAAAGL
>A0A429F943|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC 04229|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPTADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVKHFVD
KCRAGADYAITQMFFQAESYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PPELKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A3N5SQU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MDKIFHVELQTPKRSSEDIDKDLATFEDKYRKVIEAGWIVCITDNPMGLLSYGAMETIDL
LGLPVHPEQLMVHLNTFHPRKELDEILGAFAAAGGRHLLVVSGDGSQRLHRLEPEEIGIE
CTTVTSVELIRYIDREHPGRFTCGVAFNPYEPLDAEIEKMKRKVGAGASFIITQPIIGRD
DRLAGLEPFRLPVILDAWMSKKLHLLSECVGHEIPEGTPYDPMENLRELRRHYPDYGLYL
AILGFKTQYPLLQGIWEQPQA
>A0A444J2J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electrothrix aarhusiensis|TrEMBL
MLRTALNTPDEFTVTFELVPRQGFNRKQVDPLLDFAQQAKEDGRIKALSITDNPGGNPAL
APVAIGAELIKIGIEPLIHFSLKDKNRNQIVSHIYLYQRLRLRSLLVLGGDFPHPGYYGR
GKPVYDLDTIQALQLLNDMENGHYPDNQSKKNKYPAPSILTGCVVSPFKASEAEQVWQYV
KLLHKIKAGADFVITQVGFDICKFEELTEFLHEQGIKIPLLANIFIPTLPLARALSAGKM
PGILLSEKLVQQMEAEAAAGANRARLDRAAFMVSRLKKCGYQGVHLGGVNLRFKDIAYLL
DRVEQLDREGIPDNAHYDFPIPGTWYYFQHHVPEDKGKKAAEPAAEPLSPGTLLNTTWMH
RLGHNLLLTDQYITGRLFARFCLFCAKSSYRFNILLWLEKTVKRQVYNCQMCGECTLSHT
AFLCPQWHCPKGLVNGPCGGSNQGRCEVDPERFCFWVRVYNRLDKRTTLASLAAPPHLPP
KDWHREKTSSWVNFFSAQQKKQD
>N0CKD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces fulvissimus DSM 40593|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRIEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPLAEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A0M3F105|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKEQTGLEAAPHLTCIDATREELSAIARDYWNNGIRHIVALRGD
LPPGSGKPEMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPHWMSKMYE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1F9ISJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFCSPLOWO2_02_FULL_50_16|TrEMBL
MQKRVIDIIRDTQKAGKHCLSFEFFPPKSDEGLSKFYEVARQLKTARPSFVTVTYGAGGS
TRERTLDMCSWLKEELKITVVPHLTCVASSKNDIKNIVGEFKKQDFLNIMSLRGDPPQET
CQFTPVSDGFRHANELVSFLKMEFPEICLGVGGYPEKHPEASSFEEDLHFLKRKVEAGAS
FITTQLFFDNTLYYRFVEAAQKVGIGEAVPIIPGIMPILSYSQIKRFTHMCGASLPKKLV
HKLEKAENDPEAMELIGIDWATKQIDYLFKENVPGIHLYILNRSRAALELSKRLQF
>A0A330EQG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPCV
>A0A853J9D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas sp. SJ-92|TrEMBL
MTPISFEFYPPKTDDQRAQLDRSARKLKAYGPEYVSCTFGAGGSTLSYTPETIRGLREKH
GFDAAPHLSCVGGTREEIRTLLQHYRELGCRRIVALRGDLPSGMGHPGDLRYASDLVAFI
RTEFGDAFTIEVGCYPETHPQADDALADLRHFKAKVDAGADAAITQYFYNADAYFYFVDA
ARRAGIEVPIVPGIMPIANFTQLRRFSEACGAEIPRWIGKRMQAYGDDAESVRSFGADVV
AGLCERLLAGGAPALHVYTLNLARPTQTLLERLGAVRAPA
>A0A1V4VVS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelotomaculum sp. PtaB.Bin117|TrEMBL
MDAANITDCQTAVVRMSSIGAGIHILREGVEPVVQMTCRDRNRIAIQSDLLGAYSLGIRN
LLCLSGDHQMFGNHPTAKNVYDVDSIQLIRLVRRMKDEKLFFSGEAFNGQEPRFFVGAVA
NPFADPFEYRVDRLEKKINAGAEFIQTQTIYDLERFTRFMEMCVARGLHERAYILAGVTP
LKSWRAARFLQTSVPGMIVPDEIVRRLKSAEDPREEGKNICLEQIRYIKEKVKGVSGFHV
IAISWPEIVPDIVKGSGLYPRPVID
>A0A484NZ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|plant metagenome|TrEMBL
MGVAVVRKPALHACYSMEVSAKDIPALTEVAPRLPPASTIAIPYLAGEGNEARLAAARAV
RELGFEPMPHISARRVASLAELHAFVERAAAEAGVERCFVIAGDPSTPKGPFPDSFSLID
TGVFERAGIKAIGVGGHPEGHPVMSVADRWEVLERKCRSIERRGMAPSIVTQFVFDADVV
LTWLEALRARGIAHPVRVGVPGPAGVAVLARYAAMCGVGACASMLSKYGISLGKLLGTAG
PDRFVDRLAAGLTQAHGTVSLHFFPFGGIAQSVRWIEQYRAR
>A0A843A2B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MFSIKPSRRWQPAFYPFKKEKFGRRFLGKTELFVKGPLFGCRMCGNCLLQETAFICPMEC
PKGMRNGPCGGTTPSKNCYIDETRKCIWYCIYKRAEKLGRQEMLLEVLPPLDWEKVGTET
WGEVVRQIRKTGTAKFIRNIFSKDKEKKSKTWDSVFKTIRQPIWWQGDSDYHAPAYHEPV
SELERRLRSGEFVVATEVTPPLNANSDKLAKNIELVKPYVTAINFTDSSSARPRMSSIAC
CKVALDLNVEPVLQIAARDTTRTGLQADIIGVNELGIFNVLCITGDSAKVGPSPMSSLNL
LDIDSVQMLWLLRRMRDEGIYLDGRKMKNPPKLFLGAASSPFASDPGLQAIRDHK
>A0A7J4S7P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MIPAESYRGRLERALRSGRPVVTCEIGSPDGTDPADVRKRAKLVRDYVDAVNVPDNTGGV
VHAAPIAACAILAQEGIDPILHMTCRDRNRMALQSDMLAANLFGIRNILCLTGDHMIHGD
QPQTKPVYDIDSIALIDVANHLTTTGTYLSGRAIKPPPDLFPGCAAAPFAPPYEYRPVRL
GKKVQAGARFVQTQIVFNVDRFREFMGRVHDLGIDKKVPILAGVAPIRSVKAATFMRDEV
PGMEVPDRLVRRMEAAGDDKKKREAEGIAICVEIIEEIRKIPGIAGFHIMPIAWESAVAK
ISRDAHLQPATAAPRPPPEAPVPAPIAVPVSAASVSPVRGT
>A0A662K021|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MSYRSNLERILMNRWFAVTAEICPPKGSDPSRIKQKGDILRGCADAFNVTDNQTAVVRMS
SIAGSVILSNMGLEPIMQITCRDRNRIALQSEVLGAYAVGIRNMLFITGDHQSFGNHPSA
KGVYDLDSIQLIHVVKNMRDNGLFQNGEEILFGKPDIFIGAAANPFVDPYEMGVDRLEKK
ITAGTDFIQTQSVFNLERFNEWMDEVRARGLDKKISILAGVTPLKSLKMTMRMKYHVPGV
DVPDEIVNRMKNTRDQKKEGYEIAVEILREIRRIRGVHGVHITALFWEDIIPFLVKNTGL
FPRP
>A0A831XPA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halothiobacillaceae bacterium|TrEMBL
MPIPVSCEFFPPKSDEGAARLREAYQTLAGAIAPEYFSVTFGAGGSTQTRTFETVREIQR
DSGIPAAPHLSCIGSSREGIAAILDDYREQDIRRIVALRGDLPSGMQDPGDFRYANELVA
FIREHSGDWFHVEVAAYPEIHPQAPNAEADLANFKRKVEAGADAAITQYFYSIEAYRRFL
DDCERLNIDVPIVPGVMPITNYQQLARFSDMCGADIPRWLRKRLEAFGDDLDGVRAFGHD
VVSDLCRELVDAGVPGIHFYAMNRSGPVIRLCEDAGLIGD
>A0A484TVJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|plant metagenome|TrEMBL
MDVAVARRPPLHDCYSMEVSAKDIPALTAVAPRLPPASTISIPYLAGEGNAARLAAARAV
RELGFEPMPHISARRVASLAELQAFVARAAAEAGVERCFVIAGDPSTPKGPFPDSFSLID
TGVFERAGIKALGVGGHPEGHPVMSVADRWEVLERKCRGIEGRGMAPSIVTQFVFDADVV
LTWLEALRARGIAHPVRVGVPGPAGVAVLARYAAMCGVGACASMLAKYGISIGKLLGTAG
PDRFVDRLAAGLTPAHGTVSLHFFPFGGIAQSVGWIEQYRATRKQNTR
>A0A6H9LNG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MYVIEHLNKATKPLFSYEIIPPLRGKSARDILDIVEEILPFDPPFIDVTSHSAEAYYEEL
NDGSIRRHIRKKRTGTISICGIIQNRYNIDTVPHLLCRGFSKEETEDAMIELGYLGIHNV
LAIRGDETNYIKPVDNSKSVNAYANELVKQLNSLKKGQYLEDISNSDPIDMCIGVGGYPE
KHLEAPNFKSDIQYLKAKVDAGADYIVTQMFFDTSYYTSFVKQCRDAGIEVPIIPGLKIL
SGTRQITSLPKNFNVTIPEELADEVAENPDHVREIGVNWAVKQCEDLLNCGTRCLHFYIM
NDTKAVTSVIKKL
>R7ZKD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sphaericus OT4b.31|TrEMBL
MGLLEKLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLETRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLEEI
LVTVEEQATVLLAGNPDGLLLETYYDFEELTATLSMLRTKTNLPIIAQVSMHEPGVLQNG
MTLNHALHELETLGADVVGVNCRLGPHHTIQAFEGVELPDKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVALRDQGVRLIGGCCGTTPKHIEAVKKYLEELAPVKQKYAKPEKIEI
VREAEPATYEPLHEKVKRERSIIVELDTPRHLEIDGFMYGAKKLYDAGADVVMMADNSLA
SPRISNVAMGALLKGTQGIRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKIIEIYEATKHLDTPIYIGIMPVTSYKSAEFLHHEVPGI
KLSDDALARMKVCGEDKERATLEGIAIAKELVEVASEYFNGIYLITPFLRYDMTLELMKY
IEQLDEQKKGVRIDG
>A0A2E3F7S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leeuwenhoekiella sp|TrEMBL
MKITDHIKKADGKTLFSFELIPPRKGRSIQELYDNIDPLMEFKPPFIDVTTSREEFVYIE
KEDGLLDKKITRMRPGTLGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIHN
VMALRGDAMKEQQYFEPTKGGHEYALGLVEQIADLNKGRYLNNVIETSDCSDFCIGVAGY
PEKHLEAPSLKTDLKRLIQKVEAGADYVVTQMFFDNKKYFEFVDMVRAEGIDIPIIPGIK
PIAVKRHLQLLPQVFKIDLPQELIDAVEGCKSNTDVRQVGIEWAIQQSKELMEGGAPVLH
YYSMGKSDNIQAIASELF
>A0A0M9ED59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Magnetomorum sp. HK-1|TrEMBL
MSLKTPSKLEKILASGQMAVTSECGPPRGSDPEDIIKKAELIKNHVDAINITDNQTSVTR
LCSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAASFDIHNMLCLSGDHQSFGDCK
LGQNVHDLDSIQLIQAVRMMRDEAKFLGGDAIKTPPKMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNLEKFEKWMEGVRERGLHEKVHILAGLTPMKSAGMARYMKNRVPG
MDVPEEVVKRLAGVPKDKQAQEGIDICIESIERLKSCEGVHGFHVMAIEWEEKVPEIVER
TGLYPRPTIDK
>A0A229SRN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis vastitatis|TrEMBL
MTSVIERLRGDGPKFSIEFFPPRDTADEAVLWKAVRELEPYDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYASVGVRNILALRGDPPGDVYGDWI
PHPEGLTYAEELVQLVRELGDFCVGVSAYTYGHPRSPDLETDTKYLVRKLRAGANFAIAQ
LFHDAEDFLRLRDRVAATGCDVPVLPGVMPLTTMRTLQTTIKLSGAPAPRKLLDRLEPLA
DDPKAFRAAGIDVTTELCEKLIAEGVPNLHFYTFNRSKATREVIARLGLVPARA
>A0A3A6JK83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. AF38-1|TrEMBL
MKIRDLITQDKATLSFEVFPPKKDTDFADVEAAALGIAAFKPDYMSVTYGAGGSTKGHTI
QLAQEIQEKYDVPTIAHLTCVCASKEGIRTALADMKNAGIENILALRGDIPKNYDGQVFA
EFSHASELVELIKETGDFCVGGACYPEVHPDSANKHEDIIGLKKKVDAGCDYLTTQMFFD
NNIFFNFMYRIREAGISVPIIPGIMPITRRVQVKNAVKLSGCNVPERFKSIVDAFGDTEA
AMRQAGIAYATDQIIDLMANGVKHIHVYSMNKPEVAAGIQKNLSEILKI
>H0UR05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermanaerovibrio velox DSM 12556|TrEMBL
MFVKDMFRRGRPVVSFEIFPPRGGVPVEEVYRTLGAIRDLKPDFVSVTYGAGGGTRDSTL
EIASVVKNRFGLEVMAHCTGLCHGPVEVDEMVEDLMYEGVYNLLAMRGDPPRDGGVPRDP
AFPHAVDLIRHLRLAFGDEVCIAAAAYPEGHVEAEDLEEDLRYLKEKVEAGVDFLVTQLF
FDNELFYRFMERIRAMGIGVPVLAGVFPVLNPKQVERIVSLCGVSFPPKFTRMVARYADD
PGALAEAGVAYATEQIVDLLAFGVDGVHIYTMNRPDTTRRIMNNIGLVSGRG
>A0A0C3PPC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phlebiopsis gigantea 11061_1 CR5-6|TrEMBL
MAMRLADRIKTYISDRPFFTLEFFPPRTDQGFENLLLRIARLASLGPLAVSITWGAGGNT
SDRSLELAGLAQHDYDIPTVMHLTCTNMEKGSIDEALNAAKERGISSILALRGDPPRGDE
DWIPTDPRFVHGADLVRYIREQPEYSDFSIAVAAYPDGHTESTTDEDGEIEYLKQKVDAG
ADYIITQLFYDVDGFLRWEKKVRAAGITVPIIPGVMPIQTYSSFLRVTKLCGTKIPVKVM
SELVEIRHDDQKVKDYGVNLAISMIKRITTEANIPGVHLCTLNLEKSVQRVISELGWSFP
NYSKPATNKLITDVSAPSTPTTNRPSDLVISPHKATDSATSKLAVVAKQETEGGKGELNN
AASWDDFPNGRFGDYKSPAFGDPNPWGTSNVSRPQAVQWGHPKTDADISGMFLRYLHSKL
ATTPFSPEPLFPESLMIIQHLERLTKKNWWTVGSQPAIDGAQSADEVVGWGPKGGYVYQK
CFVEFFVEQADVERIEKKIQDKGLGWIDYFAASAEDEFRTNVPDGGRNAVTWGVFPGQEV
AQSTIIEKESFLAWKDEACSIWADWASFYPPESAERKLLEGIRTRRWLVSIVHHDYKDPD
ALWKFLFEDEALV
>A0A1V4Q5V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp. i37|TrEMBL
MTSSPPALSVVERLAAPPANGVVHFSVEFMPPRDIEGEARLWRAVRVFERLDPAFVSLTY
GAGGSTRDRTVRIAGELATQTTLLTVAHLTAVNHSIAELRALVGSYADQGITNLLALRGD
PPGDPLGEWIRHPQGVQYARELVELISGLGDFHVGVASFPEGHHRARDLDQDTDVLVGKL
RAGAEYSVTQMFFDVEDFLRLRDRVARADPEQAAKPIIPGLMPITSLASARRMTQLSGSV
IPPAVEQRFAEAAGDGPEEDRAAVRAVGIDFATETAQRLIAEGVAGLHFCSLNFAKATCE
VLDRLGVGVPDALPTVGAR
>A0A2D8KQI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gramella sp|TrEMBL
MKVTDHIDKANGKTLFSFEIIPPKKGKNIQELYDNIDPLMEFQPPFIDVTTSREEFVYVE
RDGLYDRQITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFTKQETEYLLVDCQYLGIENV
MALRGDAMSHQRYFEPADGGHNFATDLVKQIKNINKGRYLHDVVETDHLSDFCVGVAGYP
EKHMEAPSLKSDLKRLKEKVDAGSDYIVTQMFFDNSKFFEFVKEARAMGINVPIIPGIKP
VAVKKHLQLLPQVFKIDLPEELINEVEKCKSNKEVREVGIEWCIKQSKELMDFGVPVLHY
YSMGKSSNIEKIASAIF
>A0A1Z8RQ81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium TMED40|TrEMBL
MNSGNSIRRIFEEKRPLFSVEFFPPKNEEGGKRMIRTAAALQPYKPDFVSITYGAGGGTR
ETTMRYATILKEEHGFEVMPHLTCVGHSTYELMEILEGFAEAGFRNVMALRGDPPQGENE
FRVTEGGFRYASDLVALIRENFPDFGIGVGGYPEKHPEAPDFETDMTNLKTKIDAGADFI
TTQLFFDNQAYFRFVENCKNAGIQIPILPGLLPALSLGQVQRFCKMCEAYLPAKLEESLQ
DSPTENHPDIGAKWALNQVSELLQENCPGFHLYALNKPESTLAILEGLSRNP
>Q6AMT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotalea psychrophila (strain LSv54 / DSM 12343)|TrEMBL
MLVRDLLEHYSPTFSFEFFPPKNKEGEERLLQTLKQLIPLAPSYISITYGAGGSTREKTH
DLVLRIRRETNLTVVSHLTCVGSSRAEILRILKRYDEAGIHNILALKGDPPAPTDDAAET
VDDFLYAADLVGFIKRHFPHMCVGVAGFPEGHPETPNRLQEIEHLRQKVEQGADYIVTQL
FYDNHDFYDFSERCLQAGITVPIVAGIMPVASKKGLIRTAELAAGARIPAKLLKIVQRAE
NDTMVRKVGIHWATEQVRDLIDQHVRGIQFFTLNTSTATREIYDSLGVSNSQQLQG
>A0A7L2ZRH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prunella fulvescens|TrEMBL
MVNETQHTCNASSSSRSEGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7W7E2F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MMIAPQSESREEALLADLLSHYSIEVTSRDLQSLESMTATLQQGCEVFIAHLPKEDIGLL
VRAAAGLRDAGFVPIPHIVARNIRNRLELDTMLARLSEEAGVRHALVLGGDRDDAAGAFG
SSLELIETGLFQAYGIDRIAIACYPEGHPRIAGAILDAALTAKIDAAARAGLDVLLVSQF
LFDPKPLLNFARRLRERGVTAPLSVGIAGPASRTKLLKYALRCGVGASLRALRERSEIAR
NVLSGETPEELLMEIAAAQATEPDLGISGVHFFTFGDPAQSIRWAEQQVDR
>A0A6I5HYP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4913|TrEMBL
MALGTPSTRTDHARTVREMLATGETSYSFEFWAPKTEKGERNLWNALRRVEAVGPSFVSV
TYGAGGSTRAGTVKATQDIAAESTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGPWVEHPQGVKYAADLVRLIKEAGDFCVGVAAFPERHPRSTDWDTDVRHFVD
KCRAGADYAITQMFFDPDAYLRLRDRVVAAGCDTPIIPEVMPVTSVRQLERFPQLSNAKL
PEELKERILAVKDDAAAVRSIGIDFATRFCAKLLSEGVPGLHFITLNNSTATLEIHENLG
LHRQS
>A0A7H0JYY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium lujinxingii|TrEMBL
MFEASPSTRLSASAPIDREGAPVIRRPRPRQRTALSFEIIPPRPTDDVAKMDELIAGLAS
YNPDYVSVTSSRRSEWLEGTASVISRIEQTTDLRTIAHLACTAGTREELTEWIRTLIDAG
VRGFLALRGDLPETGLPDGYMPYATDLLNLIEEVQEEEAFRLAGGKLALSVACYPKGHEE
SRNFDHDLDVLLTKQRLGADFAITQLFFEAQDFLEFVEVARLAGVRIPLIPGIMPMTSLK
RVRRMGELSGLEVPEVVEKRLLEADDEYEAGMELTANLAREILDAGTGGLHVYTHNNLAV
TRDFLDRIGIQ
>F8N9G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella multisaccharivorax DSM 17128|TrEMBL
MSITKILTGNEQAQGFSIEVLPPLKGNGTELLFDHLDMVRDFEPNYINITTHHSEYIYRE
TDEGQYERMRIRRRPGTVAVAAAIQKRYKTVVIPHVICSGATREDIEYELIDMQFLDINN
VLLLRGDKAKDDRMFTPINGGWTHTTELIQQVNRFNEGFFADGIPIRHPGRKFHYGVAAY
PEKHEEAPNIEMDMRYLKEKQDLGAEYAITQLFYDNRKYFDFVKKARAMGITIPIVPGIK
PLAKLSQVTQVPKTFHCDMPQELAQEAVKCATDEDVRQLGIEWAVNQCKELYRSGVKDIH
FYTVSAFKSMPDILKQIL
>A0A3C0S967|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospina sp|TrEMBL
MKICKILRDTRPAFSFEFFPPKDDDGFDQLFKTIDRLKSWNPAFVSVTYGAGGSTRSKTI
DLVGRIKNEIGLESMAHLTCVGHDSQEIRSVLESLRDKGIDNVLALRGDPPKGDTDFVKP
ENGFGFASELVEFTHKDFSFCIGVAGYPEGHPECPDPREGLKHLKNKIIAGGSFIVTQLF
FNNKVYFNFVKELQDIGVDTPVIPGIMPILNFQQIRRFTKMCGATVPDELLARLESVQDD
PDAVREIGIDHATAQCGELLSQGAPGIHFYTLNRSRATLSVLERLKSLSIDS
>A0A0J6XCV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces roseus|TrEMBL
MALGTASTRTDRARTVRDLLASGSKSYSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSV
TYGAGGSTRGGTVKATQQIAADTTLTPVAHLTAVDQSVAELRHVIGQFADAGIRNMLALR
GDPPGDPMGPWVKHAEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVQKAGCETPIIPEVMPVVGIKQLDRLPQLSNAVF
PAAVKERMLAVKDDPAAVRSMGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQRA
>A0A3A6HCQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium TF09-2AC|TrEMBL
MKIRDILAQGKPTLSFEVFPPKTEDNYNTVEKAAKEIAKLKPAFMSVTYGAGGGTSDYTV
GIASDIKEYGVTPLAHLTCVSSTREKVQGVLKELKAHGIENVLALRGDIPENGQTPKVYH
YASELIREIKQSGDFCIGAACYPEGHVESANKSVDMDYLKQKVEAGCDFVTTQMFFDNSI
LYSYMYRIREKGITVPVIAGIMPVTNAKQIKRITQMSGTYLPSRFMSIVDRFGDHPAAMK
QAGIAYATDQIIDLIANGVNGIHIYSMNKPDVAGKIKENLSEILGNEYTCTP
>A0A4R4Z6Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora elongata|TrEMBL
MTAVVDRLRTEKTTFSVEFFPPRGDDEERILWRAIRELEPLDPAFVSVTYGAGGSNRDRT
IRTTGRIAQETTLTPMAHLTAVDHSVAELRNVIGWYAASGVQNVLAVRGDPPGDPNGEWL
RHPEGLTYAEDLVRLVRELGEFCVGVAAFPHGHPRSSDLETDADHLVRKIRAGAGFAIAQ
LFLEPEYFLRLRDRMAARGCDVPLLPGIMPITTPRVLGKFGELAGVPVPTEVSEQLLPLA
EDPAGFRAAGVDLATRLCERLIAEGVPALHFYTLNRSKATRQVVANLGLGAG
>A0A099T8M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobacter sp. 16PALIMAR09|TrEMBL
MPAPTVSFEFFPPQSLEASFRLWETVRTLAPLDPTMVSVTYGAGGTTRALTHEAVATIHK
HYGLRVAAHLTCVDATRAETLEIADQYAAAGVTDIVALRGDPPKGSGQFTAHPEGFRHSV
ELIEALSSTGKFNLRVGAYPDRHPEAQNDMADIFWLKAKIDAGACEAITQFFFEPETFLR
FRDKCADAGISAPIIPGILPIENWAGTKRFATRCGTPVPAELDAAFETAIRDGREELMSL
AHATELCSTLMDEGVDHLHFYTLNKPELTRDVCAALGVTPEVKLEEVA
>A0A0Q8LKP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Root180|TrEMBL
MSIDLSAPPVPFSFEVYPPKSEAGTLALHETILRLAEVGPRFISVTYGAGGSTGGRSLDL
LRHILRETPVAPLAHLTCVGNTYAGANALIREFLDAGVTSFLALRGDPPTGAEDAEAFLG
DLESSAQLVQLIDRVQAEREPYTEQAIPGVPGAVRVEPRPKVDIAVAAFPNGHPRSRHPR
EHIDALLAKQAAGATLAITQLFFHADDYLAFVQRSREAGVTIPILPGIMPITSPGRLRRV
LELSGEELPSELAIALEVEPTPEGQRALGVAHAADLARDVVAGGAPGVHLYAFNSHDTVL
AVLRDAGILTHPLEQEAAR
>A0A840WUM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubricella aquisinus|TrEMBL
MAKILQFGRRSASVQPTTTLGSFLEGFSIEVMPRTASKIESFKAILPAGTRVYIAHIDGT
PFEEMHATAKRITEEGFPVMPHLPARSITDKAEFTNWVSAYADLGIDQALLLGGGNAQPC
GEYDNSMQLLSSGVLDAHGFKRLHVAGHPEGNRDIDPDGSDRMVMDALRWKQAFRDRSDA
EMAIATQFCFEAAPVIAWVDKLAAEGITLPVHIGVAGPAKLQTLIKFAMACGVGPSLNVL
KKRAADLTKLMLPFTPEEVLRDLAAHKAANPDFGIEAVHFFPLGGITKTAEFTSAHGSVP
AARTA
>A0A4Q8Y0X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MVLKNDARDRNIRVSFEFFPPKSEEMEGQLWHTVSQLQDWDPDFVSVTYGAGGTTRAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESHDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRPAAKSAGAAA
>F8G600|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida (strain S16)|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSTERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSCQATPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFALARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPMWATRLGAQVLHKVEHAVKHPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTALLTERLIPCIELETRHRSSWPQWFQAQTP
RQLSPQPAPRTQPES
>A0A831JSL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
MKVIDLIKNSKEPVFSFEILPPLKGNSIQKVYHIIDKLREFDPKYINITSHHSEIVYLPQ
PDGNLKKTTVRKRPGTVAIAAAIQNKYGIQAVPHIICKGFTKEETEYALLDLNFLGINNL
LLLRGDSKPLDIAEKDLCLYHEHATDLQEQVNRFNQGIGLDGSKIEGIETPFSYGMACYP
EKHEEAPNMESDLFYLKEKVRNGADYVVTQMFFDNEKYYAFVERCRQEGIDVPIIPGIKP
VVFKNQLNVLPKVFRTDIPEAFASELRKCTTDEEVKAVGVEWCKAQCKDLLAHGVPGLHF
YTFMASDSVYKVAKEVY
>A0A498EWL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobellus sp. Atlit-31R|TrEMBL
LSCVGGSRESIRAILQQFQDKGIRRLVALRGDLPSGYGAGGEFRYANELVEFIRKETGDW
FHIEVAAYPEMHPQARSPQDDLQAFARKVQAGANAAITQYFYNADAYFDFLDNARKLGVD
VPVVPGIMPITNYTQLMRFSDMCGAEIPRWVRNKLASFGDDSASIKAFGLDVVTSLCERL
LAGGAPGLHFYSMNQAAATTAIWQRLVK
>A0A6P5Y4C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Durio zibethinus|TrEMBL
MKVIEKIQSLQEDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRGKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMTGFCKT
KIPAEITAALEHIKDNEEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRCLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSRN
PSYGALSDYQFMRPRARDKKLHEEWATPLKSIDDIQEKFKNYCLGKLRSSPWSELDGLQP
ETKIIHEQLGSINLKGFLTINSQPAINGERSDSPSVGWGGPGGYVYQKAYLEFFCSREKL
NELVNKCNSFSFVTYFAVNKNGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFMVW
KDEAFEIWSRAWASLYPDDDPSKNLLEEIQSSYYLVSLVDNDYIGGDIFAVFEDL
>A0A373B9D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM25-23AC|TrEMBL
MNLREYLKTTNLITDGAFGTYFAAKYQTQDIPELANITATEKVKKIHEEYLNAGAKFIRT
NTFASNTETLQEDFAEVEKNIQAAVEIARDAVNGRDAWIAGDIGPIPVNGAEDAAAAADE
YYQIAKTFAECGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGCPGDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIGEMSLWDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLSVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTKEDAARLRRIKEETGAKILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>A0A1R1RC08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. UFLA 03-321|TrEMBL
MTETISSVPNAPRAPKAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTITRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVTGIKRRHADIEISVSAYPEKHPEAKDFDADIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A367J3J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus azygosporus|TrEMBL
MKIIEKIEQAQKNNKINYSFEYFPPKTELGYANLIDRIERMAKLGPEFISCTWGAGGSTH
ERTLELCSTTQSVYGLDTCMHLTCTNMEKDKIDIALKQAKEAGIQNILALRGDPPRGHEY
WTPIDNQFTHAIDLVKYIRQQYGDTFCIGVAGYPEGHVDSPNKEQDMQYLKEKVDAGADF
IVTQFFYDPEAFINWMQNIRHIGITVPVVPCIMPIPTYQSFRRMIHLCNVKVPTEVMKDL
DEIKSDDQKVKDYGVRLAVNIINELHKRANICNFHISTLNLERSTRLILEQLGLIHHTEK
LTANKPSPWAPVHDPIKVEMWDEFPNGRYGDSRSPAYGENTYSLNQILPTSQAILKWGQP
QSEEDVRQLFKRYIQGELDSLPWCEESPQTETGTICQQLIHLIEQGYLTISSQPAVNGAP
SDDKVYGWGPKGGYVYQKAFIEFFISDQAVSELLARLSKDPSVTFYAANRKGDFVTNVTD
PDAQNAVTWGVFPSKEIIQPTIIEKASFESWKEEAFGLWKEWEEQYTPNSPSQKLLKDIG
DRYWLVNVVHHDFQKPDLLFELL
>A0A2E2X7D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea sp|TrEMBL
MSDTNPLGAHLPLDPKPGHSSLGRLERVLRRGEFAVTAELNPPDSADADEVYDRAAVFEG
WVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMGVC
NIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESRFLSGRKLTKPPQVFLGAAI
NPFVPPQEFRPMRLAKKIAAGAQFVQSQYCFDVDMFRTYMQRVRDLGLDEQCFIMCGVGP
LASARTAKWMRSNVPGVHIPDHIIKRLEGAEDQKAEGKRLCIDIINEVKEIAGVSGVHVM
AYRQEEYVAEIVHDSGVLKGRKPWRKEPNFANEAAEARLEDADAAASATPHALAGAAAES
EA
>A0A068D5G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium huakuii 7653R|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVCRILNETSLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A3N2L2Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Isolate-043|TrEMBL
MTIPELIQRKGSKGFSIEVLPPLKGKGIDQLFAGIDSLKCFEPLYINITTHRSEMVYKST
ADGLYQRVSERSRPGTVAVAAALQQRYGIPAVPHIICSGYTKAETEYALIDLRFLGITNL
LVLRGDKARHDNRFIPNTGGHAHAVELQRQINDFNNGTFVDGTTMDSANDSPFSYGVAGY
PEKHDEAPNRDIDIAWLKNKIDNGAQYIVTQMFFDNDSYFSFVERCRQSGITVPIIPGIK
PIVTKGQLTVLPKVFHVDIPTDLARAVMDCKDDVQAKEVGVEWMAMQMRGLYEAGVPSVH
IYSLNATRSVEKALRLVL
>A0A653A466|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfatiglans sp|TrEMBL
MSEYKSGSNLEKVLKAGHFAFTGECGPPMGANVEHLKEKAHHLKGVVDAVNVTDNQTAVV
RMSSWAASLILLQEGIEPNFQMVCRDRNRLAMQSDILGVYSHGIRNMLCLSGDHQKFGNH
PESKNVFDIDSMQLINLVKTMRDDGKFLNGQDVDVPPKLFIGAASNPFADPFEFRVYRLA
KKIAAGADFIQTQCIYNMDKFRAFMKQVVDMGLHEKCYILAGVTPMKSVGMATYMAKQVP
GMDVPDSLLKRLRGAGKGKVAEEGIRFALEQIEEFKQMEGVAGVHLMAIEWEHRVPEIAE
RAGMLPRPQV
>A0A1G7L3K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus arciformis|TrEMBL
MNLRDLLRERRGPLFSFEFFPPKTPEGEEALFRTLAELRGFRPAFVSITYGAMGSTREKS
VAWTRRILELGLNPLAHLTVAGQSQKEVAEVLDRFVEAGAQNILALRGDPPKGERVFRPH
PEGFRYAAELVALIRNRYGDRLAVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRVGIGIPILPGIMPITSYPQLRRFTEVCGASIPGPLLTKLERHQ
NDPEAILEIGVEHATRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGFKPA
>A0A437GEL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium meliloti|TrEMBL
MNGRTPYPVDCDGLRFSFEYFPPKNDEMEAQLFQTVTALSVFAPAFVTVTYGAGGSTKAR
SLTTVKRMIGEMEIGNTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGSV
YEPFPGGYENAAALVEALRARGDFEISVSAYPEKHPESPDVAADIDMLKRKVDNGATRAL
TQFFFDNDDFERYLERVRSAGIAIPIVPGILPINNLTQVQKFAGLCGARVPESIVSRLGP
LDDQPEGRFREAAHIAAEQITDLVRRGVSDFHLYTMNRPQLITAVCELMGYDPELAPAQP
ADTERPVRAVARA
>A0A0M7KXZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter aegrifaciens|TrEMBL
MSDSTTPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCEAAPHLSCVGATRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLNHFVNKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVNVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPLAVWKELSVQA
>A0A7C3XVM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTDSVLEKVLRSGKLAVTSECGPPRGVGPEKIRQKAEYLRGYVDAVNITDNQTAMVRMS
SFAAGLIIRQMGMHPILQMVTRDRNRLAMQSDIIGAYAHGINTMLCLSGDHPHFGDHPMA
MAVHDLDSIQFIQMVRKMRDEGKFQGGADIENPPKMFIGAAANPFADPFELRVARLAKKI
AAGADFIQTQCIYNIEKFEKWMEGVRDRGLHEKCFILAGVTPLKSVGMARYMKNKVPGMD
VPQEIVDRMAGVPKDKQAEEGIRICVETIERLKEVKGVAGFHIMAIEWEQKVPEIVERAG
LYPRPNLG
>A0A4P5W688|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MPELSFREALSQRVLLFDGAMGTEIYARGVFINRCYDELNVSQADTVGEIHSAYVRAGAD
VVTTNTFGANRIRLGAYGLETRAKEINATGVRLARAAAKDKAWVAGSMGPTGALLAPVGK
VAPGEAYQAFREQAEVLIDAGADLIVLETFTHLAELWQAVRAVRSVNRDQPIVAAMSFPF
IGPDQMQIEGDTPETAARTVSGWGIDAFGTNCSNGPRGVQHVLERMVNVTNMKLVAMPNA
GLPQVVEGRTLYLAAPEYMAEHARRFVQLGAGIVGGCCGTTPEMIKQMRSYVRSVTAERR
TIAVEAGVQNKVPVAEPKPIAERSEFARRLYGGKFCVSVELDPPRGVDAQKAVEGAAMLL
QAGIDVVNIADGPRAVARMGPSALAQLVRAHCPMESVVHYCCRDRNLLGMQMDLLGANAL
GLRNILAVTGDPPKMGTYPDATAVFDIDAIGLISFIQMLNRGLDFSGQPVGGQTALFVGA
GCNPAHIDLDIEVARFGRKIEAGAEFFFSQPVFDPAVLLHFLERTDSFKKVPFLVGIMPL
VSLRNAEFLHNEVPGMQVPSVILDRLRNAGDRDAQREVGIQCAQEALREVMNHPRIAGTY
VYPPFGSYKAVLRVVEVLKDRTGPTHFGPDGWIEHV
>A0A7W0T942|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MASGPLLLDGAMGSLLYERGVLHTRSYDELTLSQPELIRSVHRDYVQAGAEVIETNTFGA
NRMALARHGLVEQCAAINRAAVELARSVAGDKAYVAGAVGPTGAKFGIASISERRLARFA
LAEQIDILVLAGVDAIFLETFTSILEMETAIQVAKERGPRVPVIAMMVFDGQAKSDGGLG
PAEIADRLIAAGADVVGGNCGIGPAELYQVVVGMVGHGKPVIAQPNAGFPASVEGRTLYV
ANPEHFGVFARRMLKSGVRLIGGCCGTTPDHTRAMLGAVRMLRGEKIDEHVGSGHSAPGA
TASAPSLASPPPPAKTPIAERSTLGARLARGEFVVSVELTAPPGSDLTKTKQQVADLAKG
GVDIVNIADGPRASARMANVAVCARLVAETSVEPILHVCARDRSFLGLIAHLLGAQGLGL
KNLVIITGDPPKMGDYPFSTPVYDVDSVGLLRIAAGLNGGVDPAGKECEPTTFVLATGAE
PAAHDRDRELRRLEEKQRAGAELIMTQPVYDPRTLERFLDDVRPLGLPVMVGILPLASHR
NAEFLHNEVPGMAIPTEYRERMAKVGSGPSARTEGIKIAQEALAAVKHRVQGAYVMPPFN
RVDAALAVLEVARDRMTSR
>A0A524IH11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEGILDRMKKSPIVFDGAMGTMIYERGVFINTCFDEVCLTNPKLISQIHSEYIEAGAEVI
ETNTFGANRIALRPYGLSEKVKEINRQAVRIAREVAGDQVYVAGAVGPCLRPAQIMPDEH
AVEVEEAFVEQIGALVAEGIDLVVLETFTHLKELQLAARAARRLGTPVLASFVLNDRGET
AVGMKAAALARALDADENVDAIGINCGTGPAGVFDALQSVLPQVSRPVVVMPNAGFPRDI
GGRLLYLTSPEYFTEYAKKYIELGVRGVGGCCGTTPAHIRVASRAIKSLSGVKKHVEVRP
VAQQAVLVQVVPPERKSRLARKLVVGKKVTSVEIPPPRSSDLSGMLAKARKCAEAGVDAI
NIPDGPRASARISPMIAAIKILSEVGIEPILHYCCRDRNLIGMQSDLLGGFAAGLANFLI
ITGDPPKVGDYPQATGVFDVDAIGLTQMAANLNRGFDIGGNPIDPPTAIFLGVGANPCAV
EMEREIDRYFRKIDAGAEFATTQPVFDVEALFRFLDRVEGYERRIPVIAGVWPLVSYKNA
EFMNNGVPGVVVPREILDRMYRCRTKEEARRAGIDIARKTIEQVSSRVSGFQVSAPLGSV
EIALDVLEKGR
>A0A6L7JQ82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MTRISDLLGDEPTFSFEFFPPADEAAYKQLETTLEELSKTVPSFVSVTCGAGGAGHDRTQ
ELVVQICTSRQFPAMAHLTCVGHSRFEIAELLDSYAAAGVLNILALAGDPPDGSAVCGDF
KYALELVELIRNHPVSFCVAVAAHPEVHPRSRDRVFDRKHLADKLNQADFAITQFFFDPA
DYVQLLNELADLGCYRPVIPGVMPVIWPKSIRRYASMNGSTVPEELFARLETLSVADRFK
AAAEAAAELAQCLLDFGAPGIHLYTLNHPQASTQIARELFPKLGTRYL
>A0A7V4K0X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGLREAFQSGKFVVTAEVGPLKGTDTHEVKEVAHLLKGKVDGANVTDQQSAVMRLGSMVT
CYLLKQEGLDPILQVTCRDRNRLAIQSDLLSAHVLGIRNVLCLTGDYPTLGDHPDAKPVY
DLDSVQLVWAVNRMNQGYDLSGNELQGKTDFFIGAVVTPITDTEAALELQLVKMEKKIEA
GARFFQTQAIYDVDAFAKFMKRAEKFGVPILAGIIPLKSVGMARYMNKNVAGVFVPEHLI
DEMAKAEKPAQKGLEIAARLIKEVKDLCQGVHIMAIGWEKKVPEILELAGLA
>A0A538PSI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGSLLYERGVLHTRSYDELNLSQPELIRTVHRDYVHAGAELIETNTFGANRIGLARHGLA
DQAKAINRAGVELARSAAGDRAYVAGAVGPSGVNHGIASASERRLARFALAEQIDTLVLA
GVDAILLETFTSILELEMAIDVARERGPRVPVIAMMVFGTDLRSDGGLGPAEIADRLVAA
GADVVGANCRVGPAELYQVAVGMVGHGKPVIAQPNAGLPASVEGRTLYVANPEHFGVFAR
RMLKSGVRLVGGCCGTTPEHTRAMLGAVRMLRGEKLDERIAINPSAGPSAGDGHAAAAAG
PAPPAKTPLAERSRLGGRLARGEFLVSVELTAPTGADLGKTRQQVAELAAGGVDVVNIAD
GPRASARMANIAVCARLAAETRVEPILHVCARDRSFLGLIAHLLGAQGLGLRNLVIITGD
PPKMGDYPFSTPVYDVDSVGLLRIAAGLNAGIDPAGKECEPTSFVLATGAEPAAADRDRE
LRRLEDKKAAGAELVMTQPVYDPRTLERFLDDVGGLGLPVMVGVLPLASHRNAEFLHNEV
PGMGIPAEYRERMARVGGGPAARAEGIRIAQEALAAGKQRVQGAYVMPPFNRVESALAVL
EVARDRWRPA
>A0A7W1CPY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MTRVAELLAAGRTFSFEFFPPKTDGAQLSLGRAIAELEPLAPSFVSVTYGAGGSDRQRTR
EVVTWVRRETSITPMAHLTCQGHRRHEIAAILDDYRAAGIDNILALGGDPPSDPADARPS
DYAFAADLIDDIAAAGHFSIGVAAHPELHPRSPDRATDRRRLAVKLRRADFAITQFFFEA
DHYRRLVEELGELGVDKPVVPGIMPITNTGQVARMAAMSGTELPTWLLERLDGVDDPAAV
RRIGIAIASDLSAELLDDGAPGLHFYTLNRSTATREIYANLGLGVSQ
>A0A8E4FNC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia rettgeri|TrEMBL
MSFFHANQREALNQNLAELDYQINVSFEFFPPRSEEMEQTLWKSIDRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKDKTGLIAAPHLTCIDASRDELKGIARDYWNNGIRHIVALRGD
LPDNSNKPDMYATDLVELLKGEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPAWMSKMYE
GLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVIL
>A0A496XLE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MKVIEHLEKATGPLFSLEIVPPPRGRNIDDLLAIIEKIIPYKPAWIDVTAHPADAYYSEK
DDGTIERKIFKKRPGTIGICGVIQNRFNIDTVAHLLCHGFTKEETEDALIELNYLGIKNI
LAIQGDIPHFKKAVTNGYGVNKHASDLVKQIVDAKKGIYQTNITGAKPLNFGIGVAGYPE
KHYMAPNLKYDMDFLKQKIDAGADYITTQMFFDNKHYFSFVKNCRAAGINVPIVPGLKIL
KNVRQLKTIPQNFYIDFPDELVDLIKSNPENIEQIGIDWAVKQCRELLNFGVPVLHFYII
NEGKALLKVLDHLRPGLELSIAV
>A0A1F2A029|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. HMSC24B04|TrEMBL
MEHAHRSRQSASAPALAEDYAAEQRFPRPVRPALSFEVMPPRTRQARQVLPELIDTLESY
GPDYVAITSSAKSGWAQGTADFVRELSATTRLRPLAHLACTAAPTVELLEWVERFIDAGV
RGFLAVRGDLAPGQASPPAGHLPHADALVARVRQLERRSAARFCGGGLSLGVAAYPSGHP
ESSGPDEDLDVLAAKQRAGADFAITQLFFDTSAYSRLVRAARLAGVTMPIIPGILPITSS
ARLERMAHLSGLVPPQWLGEQLEDARCPEHARDIGLTATVELAQRVLDAGAPGLHFYTFN
DPRTTVEVLDRLGIDAMAASAVGHEAV
>A0A1G3AI51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RBG_16_64_12|TrEMBL
MVAAFRQAFAEKDFVVTAEVGPPKGTDVSELVEHIELLKDKVDGLNVTDNQSSVMRISSL
AVCRMVLDHGGEPILQLTCRDRNRLALQSELLSAWVLGVKNVLCLTGDYISVGDHPQAKP
VFDLDSVQLLQTVGLLNEGKDLAGNDMKGATDLFAGAVVTPEADPIEPQMIKFQKKIAAG
AKFIQTQAIYDLDNFKRFMDRARRDDVKIMAGIVLLVSAGMARYMNKNVPGIFVPDELVK
EMAEAPKGKALQAGIAIAGRMIRTLRDQKVCDGVHIMAIGKEGCVPDILKAAE
>A0A661LQA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MISAFKKALESGKFVITSEVAPPKGTNLEKMLHHIELLRDKVDAMNVTDHQSSVMRFPSM
GGVLLVKEMGGEPILQMTCRDRNRLALQADLLLADTKGVHNVLCLTGDSVLLGDHKEAKG
VFDLDSSQLLATIRRLEKGKDMGGNDLDGSVSFCAGAIVTPEVNPIEPQLIKFEKKIEAG
AEFIQTQAVYDLENFKGFMDYARQFPVKILAGIILLTSAPMARFMNKNVAGVNVPQELID
EMVAAPKGRALDKGIEIAGRMVKRIHDERMCDGVHIMAIGREELVPDIISAAGLF
>A0A014N545|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PRh5|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFSAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSRGGTVRATERIATDTTLTPVAHLTAVNHSRAELRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWVQHPDGLTYAADLVHLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATKLCARLMAEEIPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A661RDY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTFREALESGKFVVTAEVGPGKGTDVEHLLKDAAIIKDRVDAINVTDLQSSVMRLGSMAF
CHLLTDMGIDPVFQLTCRDRNRLALQSDLLSAWVLGIRNVLALTGDHPVLGDHPGAKPVF
DLDSVSLLEVIGKLNSGFDMAGNALKGAPDFLAGAVVNPGADNDAALDLQIMKMEKKIEA
GAKFFQTQGIYDLDMFEKFMKRVEGFRTKVLGGVILLKSVGMARFMNRNVAGVFVPEPVI
QELKKAEDKSEASINIAVRLVKGMKDLCHGVHIMALGWESKIPPVLDAAGL
>A0A3N5SLQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKAGSNLEKVLSEGLFAVTGEISPPKGNDIGAIKRKADLMKGCVDAVNVTDNQTASVRMS
SLSTSSLLVQMGLEPVMHMTTRDRNRIAMQSDLMGAAALGVRNVLCLTGVHQSLGNQVDS
KNVYDLDSVQLVDCVRMMRD
>A0A355HBD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEIPFRESDTLENDMFMEPADDLQDYLKQKTTWSMEILPHNINDVSLIPEFVNEVYITMI
PGASCWETIQTAQQIKAVGKQAIPHIAARSFADVEELSACLSELQEAGIERALLIGGGNS
EPAGDFSCVMDMLKTGLLTKYGINSFDFAGHPEGNPDDPNSEFHLLEKLRWTEERGISTR
IVTQWCLDTDSANDWISGLREKGIRNPIHIGIPGPSTIKTLMRFAKVCGVKASTQVLRKQ
GLNLSKLMFVNKPDKIISELRGYDQLHLYPFGGIEKSAAWLTERQKAND
>A0A3M1KZ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
FVATAGGFEHAIDLVRLIRSRRRNLCVAVAGYPEGHIEAPSLDADLEFLAQKVAAGADLV
ITQLFFENACYFEFVERARAKGIGVPIVPGIMPITNLKQIERFTTMCGASIPEELHRRLE
AAGDDTDRVTRIGIDHATEQCRELLTGGAPGIHFYTLNKSRSTVEIIRRLRTAPI
>A0A290XQV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp. 1D|TrEMBL
MRIALYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFMPPRDAEGEARLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSVAELRALVGAYADQGIT
NILALRGDPPGDPLGEWIKHPDGVEYAEELVRLIGTLGDFHVGVASFPEGHHRAPDLEHD
TRNLVNKLRAGAEYSITQMFFDVEDYLRLRDRVQAADPEQGAKPIIPGIMPVTSLASIKR
MAELSGSVIPPKVVERFARAAGDGPEEDRAAVRAVGIDFATETAERLIAEGAPCLHFCSL
NFAKATSEVLARLGVDVDAALHVPA
>A0A179H6N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Purpureocillium lilacinum|TrEMBL
MDKITDKIAALPPDAEYFSLEFFPPKTAMGFSNLRHRLQRMEQALRPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRRLIDKALEDAKVLGIRNILALRGDPPRNEE
YRDADDTDDGAAEDFTWAIDLVRYIRSKHGDYFCIGVAAYPEGHADESHPLGQSLEHDLP
YLVDKVQAGADFIMTQLFFDIDAYDKFEKTLREHPSGAFKDIIIIPGLMPIQSYQMIKRT
TKLSHAKMPEAIMSRLNAVKGDDEKVKLVGVDIVSELIEQIRTIKSRSTGRKGFHFYTLN
LEKAVAFIVERTGLIPDTSDNEEAVVEDTSAVPTLQVNGNVRLRTRSHSRTSRRQSSVGS
DPHNRVIVGSQRPSHPEWEASGQEAGVPAEAINSRANTLAISEGEGVLGREATWDDFPNG
RFGDSRSPAYGEIDGYGVSLHMSVASAVRLWGHPKTRQDISDIFVRHMKGQLEAIPWSEE
ELMPESSAIQPRLVELNSKGWWTVASQPAVNGLPSNDSTFGWGPPNGFVFQKAFVELFIP
SSDWKVLAERLRAPEVRDVVCFYSANAKGEFESSDVSGAANTSTGEASTNAVTWGVFPGK
EIVTPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLNGIKEDYWLVNIIHHDFVD
KEALWKLLMA
>A0A1M6DLP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofundulus thermosubterraneus DSM 16057|TrEMBL
MKTESKLQKLLDSGHFAVTAEIGPPKHASAHGIRHHAHMLKDYVDATNITDCQTAIVRLS
SIASAVHILDCGLEPIVQMTCRDRNRIAIQSDLLGAYSLGVRNLLCLSGDHQKFGNEPSA
KNVYDVDSIQLIYLMRRMRDEKMFFSGEPIKEHEPRFFIGAVANPFADPFEFRVARLEKK
VEAGAEFIQTQCIFDMERFERFMEMVRERGIHERVHILAGVTPLKSWRAAKYLQTSVSGM
IVPDDIVERLKKAEDPKREGIEICIEQIKHIRNIPGVHGVHIMAIAWEEVVPEIVERSGL
FPRPKVE
>A0A534QSP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKITDILARGGPCISFEFFPPKTPEGEAALMRTIEALKPLGPGFVSVTRTGAKPREAPVE
LVTRIRALGIEAAAHVTCIEAGREELAAHYELIESRGIENVVAIRGDRPGEGSFHPPLNG
FRYAADMIRFVRARGHKLCLVGGGHPEGHPECRDLELNIQHLKM
>A0A2E5PSG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKIADLYQKKTFVFSIEIFPPKNTESLERLKLRLEEFKSYHPDFISVTYGAGGSTRENTH
ELASFIQNDLGIETMAHLTCVSHTRQEIEEVLEQFHQSGIENLMALRGDPPSGEKCFQRP
SGGFAYAVELIQAVRSLNGFCIGAAGYPEGHVENPDKEADLRHQLAKVEAGADLLVSQFF
LENEHFLKWRDRLRREGVEIPIIPGLLLPSSPDALFRMEELCGVLIPLSLRQKLERYAGD
PNALKEIGWLHLAEQTEALIGEGIEGVHLYALNCLETIRRFSELIQPSFSFQQTYPENPT
RRSFTEKTEMHGTA
>A0A2M8EC39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium CG_4_9_14_0_8_um_filter_57_21|TrEMBL
MSPTRFPISIEFFPPKTPEGVEKLRVARQQLYALKPEFCSVTFGAGGSTQEGTFSTVSAI
LAEGVPAASHFSCIGATHARVREQLATLKAMGVKRLVALRGDLPSGYGTGGEFHYASDLV
AFIRAEMPDDFHIEVAAYPEMHPQAKSPESDVKAFAAKVQAGANSAITQYFYNPDAYFRF
IEEADALGVRVPVVPGIMPIASSSQLMRFSDACGAEIPRWIRLRLQSFGDDTASIKAFGL
DVVTDLCEQLRAGGAPGLHFYSMNQSAATLEICKRLGV
>A0A3N5TKN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MELVPGREPAGRSVDSVKGMAADAFADGRVSAVSITDNPGGNPALSPDVIGHDIFKVGMD
VIVHFTCRDANRIGMESRALQLAMMGIKNILALTGDYIGKGFAGQGAPVFDLDSVTLLVM
LRMLGKRVQQAGDPDVFFAGCAVSPFKSYRGGAL
>A0A2E4LQY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MHLIDLYQKQDFVFSIEIFPPKTEKGMEKLKTTLEKFKSCTPDYFSVTYGAGGTSRANTH
EMXAHIHHELDVPAMAHLTCVAHTEKEIDXVLTKLKNSEITNVMXLRGDPTAGTKHFVQP
KGGYHYASELIAAVRRHSDFGIGAAGYPEGHVENPDKDDDRKRLHEKIAAGAEFIVTQFF
LDNTHFLHWRDQLHKEGVSVPLVAGILPPANWNAISRLSDMCGVSIPEKLAQALIKHESD
PEVSKIIGFEHVEKQIDELLQEGVEGLHLYA
>A0A1S1D2R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC064F07|TrEMBL
MATVHPALSFELFPPRSHASCESLIRTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPADLAYALETATSNAE
LHRIGVEYALNQCRTVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEY
A
>R7ACA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides pectinophilus CAG:437|TrEMBL
MKISQIHHDKKQSLSFEIFPPKKEEDFKNIDATLEILCDCRPDYISVTFGAGGSSNNNKT
IQLARKIKEKYHVEPVVHLTCLCYNRAEIDEFVRELTAEGIENILALRGDRNPDVPAKED
FAHASDLIKYLRATTGDRFCIAGACYPDVHPETENRVDDINNLKIKTDAGADILISQLFF
DNDTFLQFVSDCRRARIEVPIVPGIMPCINAAQIQRMVTMCGAKFPERFQKLIRKYGDNK
DALFDAGMAYCQSQIIELLASDVDGVHLYTMNNVKVAKRLTEGIKNII
>A0A661IDK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MAFKEALESGKFAVTAEVGPLKGTDTTEIMEVAELLKGKVDGVNVTDQQSAVMRLGSLAT
CHLLVQKGLDPIFQMTCRDRNRIALQSDLLNAHVLGIRNVLAITGDYPTLGDHPDAKAVY
DLDSVQLVWTINRMNQGYDLAGNELEGKTDFFVGAVVTPITDTEAAFELQLIKMEKKVEA
GARFFQTQAVYDVDAFARFMKRAEGFGVPVLAGIIPLKSVGMARYMNKNVAGVFVPEHLI
EEMSKAENKAQKGLEIAARLIKDLKDLCQGVHIMAIGWERKVPEILELAGLA
>A0A2E8GSC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MIAEALSIPGPFLREARAPCTNWSLEIVPKHAESVRDLPQDIREIYITMVPGTPWVDVIA
AARTVHRLGRSPIPNITARSIPDTASLEQLLLQLKEFRVEQALLIGGGIPELAGEFTSVL
ELLQTELFEKHGLLDLDLAGHPEGNPEDPHAEQSLLDKLTWGREHGFSFRIVTQWCFDAD
TVNDWIFRLRELGVTEPLHIGVPGPATMKTLMRFASLCGVKASATVLRKQGLHLTPGCCS
>A0A534YI74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
QLGVAYATLQCADLLRRGVPGVHFYTLNRSPATRAILATLRAAEPWLEATG
>A0A4E7Q7W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis subsp. israelensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7Y8VKM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromohalobacter salexigens|TrEMBL
MSTREHPLGISFEFFPPNTDAGREKLKGVRDTLAERRPRFFSVTYGAGGSTQARTFETVK
SVRQCGIDTAPHLSCIGSDKGELRERLESFREAGITNLVALRGDLPSGMGGMGELRYANE
LVEFIRKETGDHFQIAVAAYPEVHPQAPSYEHDLQNFVRKMQAGADLAITQYFFSADAYF
HFLERARALGVEAPIVPGIMPISNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIQAF
GEEVVSNLCQRLLDGGAPGLHFYTLNQATPALRVLDNLRCDS
>A0A8H6YEL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycena venus|TrEMBL
MKITQKIRQSHKENKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTAEMVKTCQGLIGIETCMHLTCTNMPKSKVDIALREAKTSGCRNVLALRGDPPAGKEE
WEAVEGGFVHGIDLVKHIRREYGDYFDIAVAGFPQNQLLPPEERDLEMKYLKEKIDAGVD
FIFTQMFYDVDVFIAWVKSVRAAGITIPIVPGIAPIQTWNGFMRATSLAKIFIPQSFLDA
LEPHQNNDEKVREIGTKLVADMCRRILDENLDIHGLHFYTMNLEKGTKMLLEELNLVPRV
ETIKPLPWRQSLTPNRRTETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTAKDAFKLWGEPKTVGEIATLFARFCTKDLRALPWSDQAPASETSIISSQLA
RMNQYGFLTINSQPAVNGAKSEDKVFGWGPRNGYVYQKAYLEFFVNPTLLSLLLAHIERD
SNITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGQQ
WAKLYDADSPSRKIISELMDTCFLVNVVHNDFHDPEAIFEPFFKAGAEYAAMENKPEPAQ
PQMNGH
>A0A494UT06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces fungicidicus|TrEMBL
MALGTASTRTDRARTVRDILAAGKKTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVSHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PEALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A651DA72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MSDLRARLTDGEVHLLDGAMGTVLYERGVFVNVCYDELNVSRPALVEDVHRQYAEAGARI
LETNTFGANPVKLSSFGLEARTVEINRAAAARARAGIAGARLPPGVSSSSLHVVGAIGPL
GIRIEPWGPTAEAEACGYFARQVEGLLAGGVDGFILETFQDLRELAQALRAVRDACDLPA
IAQVTIESGGRTSYGTGAAEIARRLEDLGADAAGLNCSVGPAEILDAIEAMAAVTDLPLS
AVPNAGLPRTVGDRKMYMASPEYMARYARRMVEAGARLIGGCCGTTPEHIRRMAETLAAE
GDPGGDARGARPDRSPARGAAEPVVEPFPLGERSPLGRRLADGTFIAALELVPPTGWDPE
PLLDEARRARLAGVDVVTIPDAPRGRARMAALPAATLVERETGLDVVAHYACRDRHMVGM
ISDLLGAASGGVRNVLIVTGDPSPAGPYPDRTAALDIDSIGLTNVL
>A0A8B3IWY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLTIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A7V9FIF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MRTLTDLLTDNRVHVADGAMGTMLYGRGVFLNVCYDELNLRQPDLVREIHREYVRAGAQL
LETNTFGANPLKLATYGLAGETERINSAAAGLAREAAGERAAVAGAIGPLGVRLEPFGET
SVDEARQAFRSQVQGLLDGGVDSFILETFSDVAELGAALGAVRELCDLPVIAQMTVGTDG
KTHYGTDPVVFGPTIQALGADVIGVNCSVGPHGVLEAIEKLARVVTVPLSAQPNAGLPRE
VGDRKIYMASPEYMASYARRMVEAGARLVGGCCGTTPDHIRAMVGYVQSVSPRHTTTVAA
IPVPATTPEAVPLAQRSRIGAKLAEGRFITTVEIVPPKGVDPTPMFEQVRRLKAAGVDAV
NVPDGPRAQSRMGALLSALMIEREVGLETVVHYACRDRNLLGMLSDLLGAAAAGIRNLLI
VTGDPPKMGPYPEATAVFDIDSIGLTNLVSRLNRGLDPGSNPIGQPTKFVIGVGVNPAAP
DFERELKRFAWKVEAGAEWAITQPVFDLDQLDRFLSRVESFRIPIVAGIWPLVSLRNAEF
LANEVPGVTVPDAVLERMRRASALGKDAALAEGVRISQEMLTAVADRLQGAQVSAPLGKV
PVALEVLEAAPIEPVASPGYTHDT
>A0A503NZK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-4-6|TrEMBL
MTARQVDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFRTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKRERRRDDQLVADRLDHLLHDEITETQVDMVK
TAH
>A0A0C1YCT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lyngbya confervoides BDU141951|TrEMBL
MPGSVFSRTQRMALTGDIRVSFEFFPPKTEAMEATLADTIEKLAPLNADFVSVTYGAGGS
TREPTRRTLAHVQKQGGMDAAAHITCVGSTCEETDAVVREFTAMGIRRFVALRGDPQTGM
GTRYVPHPGGYENAAHLVAGLKAFGDLDISVAAYPEKHPESPDFATDIDMLKRKVDNGAS
RAITQFFFDNDTYERYVERARKAGIYVPIVPGILPIHNFRAVSNFAGKCRTHIPAWLAER
FDGLENDPKTHALIASAIAAEQVLDLVDRGVRDFHFYTMNRPDLVFAVCRLIGIREETVD
AAA
>A0A2S9B876|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MYb3|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A644UMD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MTPGNHGLPYGANSSRPMRLEDENAMHVFWQPFLLNGCFLMYILRENRSSCSGAAHKRMK
ISELFAQKQPVVSFEVFPPKPESPFETVLEAVEALHNLKPAFISVTYGAGGSTQNKTLEL
AQHIKEAYGIEALAHLTCITNSPDATEKILDEIEARGLENILALRGDPPKDWNNAVYKVH
ATDLVKRIANRKKFFIAGAAYPEGHPEAASPQEDLQHLKEKVDAGAGLLITQIAFDNDYL
KGFREGVARAGITVPITAGIMPVFSASQITHICNLCGATLPPQLVAMLDKYSHNQDALQS
AGIEYACRQINDLVAAGFEGIHIYTMNKPLLARAILSGTNLR
>A0A3R9LFK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNSETAKYIHQATHALFNHQSLG
>X5QI61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSJC280B00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVIREFADMGVKRFVALRGDPAEGVGA
AYRPHPEGYANGAELVDALKGAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEVEAA
GSAAA
>A0A1V1T895|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|fungal sp. No.14919|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTGMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
STKSLELAEICQRELNLTTCLHLTCTNMSRKMIDNALEDAKALGIRNILALRGDPPRAAE
YQDANEDPENAIDEGFVWAIDLVKYIKNKYNDYFCIGVAAYPEGHADESHPLGQSLEHDI
PYLVEKTLAGADFLMTQLFFDTDAYETFERQLREHPSGAFKSIPIIPGLMPIQSYQMIKR
TTKLSHARIPDEIMARLDAVKKDDEKVKNVGVDILCEIVERVKEIQGRIPGPRGFHFYTL
NLEKAVSFIVERVNLISSTPDEEAVVDDGPLPNIPALVINGTSSLDHHAQDISQSRRQST
VGSEPRNRVIVSERTLSHPEYEASQADAGLKAGAINTRANTLAISEGEGVLGREATWDDY
PNGRWGDARSPAYGEIDGYGPTLHVTRAQAISLWGHPKSLEDVNTLFVRHLKGELSAIPW
SEEEVHEETGTITDQLIRMNQRGLWTVASQPAVNGFSSEDPTFGWGPRHGFIFQKAFVEF
FISAAEWRTLREKLTSPEVRDTVTYYAANAAGDFVSSDLSGAAPPSGATEATDASNNGYS
VGESSTNAVTWGVFPGKEILTPTIIEEVSFRAWSEEAFGIFSEWAQVYGKGHESEKLLEA
ARADSWIVNIIHHDYMDKEALWDLLLK
>A0A1F2P643|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Syntrophoarchaeum butanivorans|TrEMBL
MRNIKEGKFVFTGELEPEKTTDLTELVESAKKLLGHCVACNVTDNPQSMAYMSSLVASYV
VQRDAGMECVYQLRCSDRNSIALTSDLLGAGALGIKNVLALTGDHTTLGDYPGAKPVFDL
DSGQLVYLIRKMVDEGVDLYGRPIHNPPKFHVGVAGNPNADPLESEILKLKRKIDAGAEF
IQTQVIFDIEVAKTFLKEMERFKVPVLIGIFPLKNYGTADYFDKYIPGVHVPKDLLAEMK
KASEISDKEKRNERYDEINLEYYGDFVHEIAHTTSAAGIHVMAVAYERITPALIERAKI
>A0A845I3L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella fentianensis|TrEMBL
MANHNFSIEFFPPKTAEGAEKLRVTRAKLSELHPKYFSVTFGAGGTTQRGTLDTVVEILA
AGEEAAPHLSCVGGTRASIRQILNEYKSHNIRRLVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQARSPQDDLLAFERKVKAGANSAITQYFYNADAYFQFVE
QTQKLGIDVPVVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VSALCERLLAGGAPGLHFYSMNQAAATTALWQRLVK
>W3A2A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora parasitica P10297|TrEMBL
MGKIIESIRSAYAARADDASARPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGAERWSPVEGGLSNAVDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIQWISDCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPEKVLTALDAIKNDDAAVRRNGTQLAVETCRRLLAAGVNSLHFYTMNLATT
VTQVLEGLQLLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRTELWGTPQTEEDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAAIRENLQWLNSNGFLTINSQPRVNGAPSSDPSVGWGGDDGVVFQKAYVEFFVA
PEKIAHLVKVMRRDYPQLSFHALNRRGDEHRNTPLHSVTAVTWGVFPGIEIVQPTVVDSD
SFAAWKDEAFELWQTQWASAYPEGSCSREVIQHIYDSYFLVNIVDNDYANDDSDIFSIFT
RIITEAMDKEELRTRVLELEARREKMFDTLASFQSLQKDLNGELRAAHSELAGVRGENLQ
LKEKVRQLEAQLALASL
>A0A7C6J927|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MKNACSKLEQTLKSGRLALTAEIGPPKHTSPEGIVANACLLKDYVDAANVTDCQSAVVRM
SSLAASLHIHHNGLEPIFQMTCRDRNRIAIQSDLLGAYSLGIRNVLCLSGDHQIFGNHPT
AKNVYDLDSIQLIQLTRRMRDEKLFFSGEAIQGHEPRFFIGAVANPFADPFEYRVDRLEK
KINAGAEFIQTQCIYDMERFSRFMELCVSRGLHQRAYILAGVIPLKSWRAARYMQTKVPG
MIVPEDIVQRMKKAEDPRAEGLEICVGQIKYIREHIKGISGFHIMAINWEESVADIIRRA
GLNRPQC
>A0A7Y9NKI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edaphobacter lichenicola|TrEMBL
MADGVGGEELVSVAGYAAADRLFDGGTVLCDGAMGTMLYARGVFINRCYDELNLSQPELV
REIHAEYLQAGAEVVETNTFGGNRFRLGQHGLQDQVRAINVAGVKLARECVNQIREKQAC
EAFVAGSIGPLGVRLEPLGKVGLEEAQEAFAEQIRALVEGGPGVGVDLLIVETMTSLTEA
EQAILAARSVAPGVCVVVMMTVDEDGNCLDGASAETAAIKLTEWGADAVGCNCSAGPATV
LSVIERMRPVTTLPLAAMPNAGIPRAVEGRTIYLTSPEYMASFTRKLVKSGASIVGGCCG
TTPSYTRAMKSSLRALGAMEGGIEVMQRDGTQKAASQKESKVVPPLLAERSKIGSMVAAG
EFVTMVEIVPPKGIDCSKELDGAMQMHRLGVDAINVPDSPRASARMSAQSLCVQIQQHVG
IETILHYTCRDRNVLSIQSDLLGASSIGLKNILCLTGDPPKLGNYPNATAVFDVDAIGLV
NVVRNLNYGLDIGNNSIGESTGFSIAVAANPGVQDMDQEVRRFAFKVEAGAEYAITQPVF
DMRVLEEFLRRIEGFRIPVIAGIWPLTSLRNAEFMKNDLRVSMPDEIMARMAKALTPEAG
RLEGVKIAQEMLAEARPMVQGVQVSAPFGRYGVAADVLGLAEVEVV
>A0A7W8J519|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edaphobacter lichenicola|TrEMBL
MADGVRSAELASVAGYAAADRLFDGGTVLCDGAMGTMLYARGVFINRCYDELNLSQPELV
REIHNEYLQAGAEVVETNTFGGNRFRLGLHGLQDQVHAINVAGVKLARECVTQIQEKQAC
EAFVAGSIGPLGVRLEPLGKVGLEEAQDAFAEQIRAMVEGGPGVGVDLLIVETMTSLTEA
GQAILAARRVAPGVRVVVMMTVDEDGNCLDGASAETAAIKLTEWGADAIGCNCSAGPATV
LSVIERMRPLTPLPLAAMPNAGIPRAVEGRTIYLTSPEYMASFTRKLVKAGASIVGGCCG
TTPSYTRAMKSSLRALDAMESGVEVMQRDPTGKATTMKESKVSPPPLAERSKIGSMVAAG
EFVTMVEIVPPKGIDCSKELDGATQLHRLGVDAINVPDSPRASARMSAQSLCVQIQQHVG
IETILHYTCRDRNVLSIQSDLLGASSIGLKNILCLTGDPPKLGNYPNATAVFDVDAIGLV
NIVHNLNYGLDIGNNSIGGSTGFSIAVAANPGVQDMDQEVRRFAFKVEAGAEYAITQPVF
DIRVLEEFLRRIEGFRIPVIAGIWPLTSLRNAEFMKNDLRVSMPDEIMARMAVATTPEAG
RAEGVKIAREMLAETRSMVQGVQVSAPFGRYGVAADVLGLSGDDEEGLVA
>A0A562WRP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter argillaceus|TrEMBL
MHFLELLTEQVLIGDGAIGTMLYGKGVGLDANFEHLNLVRPQLVSELHLEYLAAGANLIE
TNTFGANVTKLQPIGLEKKVREINRRGAELARQAVAAAGNGYPRFVAGSIGPLARLKGEE
REPDRETVTAVFREQAEALAEGGVDLFILETFADLGQLTCALEAVKGIGLPAIASMAYLE
GGRTGGGVEVETAGRALADAGAAMIGANCGAGPLEVLRVVERLARVTDRPLAAFANSGFP
EYVDGRYLYRCTPDYFAEKALEMVAAGAGLIGGCCGTTPDHIRRLAERLAGMRPAPRRVG
QPVRVSELKPAEPAAATGFLSSWGIRPVITVELDPPRGLDCGKILAGARLLKEAGADAIN
LAENPLARVRLGNIALASLIQREVGIEVIVHITCRDRNLLGLQSDLMGASLLGIRSILAV
TGDPARLGDQAAASSVFDLNSFTLIKLLSDLNRGVNALGHPIDHGTGFTIGAAFNPNSPK
MEVQAARLAKKVANGAGFAQTQPLYDTERVLAMLEATRDLSIPLLPGIMPLVSERNCEYL
HNEVPGIVIPDRIRERMHGKEKEAGVREGLAISRELIDTIRGEVGGYYLIAPFGRAEIAA
DLVRFIREGQR
>A0A1H6C7C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora kobensis|TrEMBL
MTSDAELLQQSLNNARFEVLPLKGVLAQAELLPAGTTVTVTASPGKGIEATLDLAAGLRD
RDLHVVPHLAARMIGDRAHLTALLDRTDDLGITEVFVVAGDSQVPRGEFPDALALLRAMD
ELGRRPDRVGITGYPEPHAFIPDATTVRAMNEKARYADYVVSQICYDPQAVASWVKAVRA
RGVLLPIHLGVPGVVDVHRLLRISLRIGLGESIRYLRKQHGVVSKLLTRYTPEELFDGLS
PHLVDPSCGIAGWHFFTFNEIAKTVQWRHDLIARLREVPA
>A0A0A2C833|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus str. PAC1|TrEMBL
MKSKLQKRLESGLSAITAEIMPPRGGNTASAISKAIKLKDLVHGFNVTDGSRAIMRMSSL
ALCKLLLEANLEPVLQLSCRDRNRIALQAELLGAHALGIKNILCLTGDPVRVGDQSQAKS
VQDFNSIELIRQVTSLNKGIDPVSDLLPDGPTNLFAGAAADPNCRGFDGLRRRIELKKNA
GANFLQTQMVMDPKVLERFCKEITEPMKIPVLAGVFLLKSAKNAQFINRVVPGACIPESI
ISRLESSSNPIDEGISIAADQVKSFLGIAQGVHLMAVKAEQQIPIILDRANIN
>A0A4P8I968|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerostipes rhamnosivorans|TrEMBL
MKISELLKEKATISFEVFPPKNKEGDISSIYHTIGELKKLNPDFISVTYGAGGSSKGKTV
EIASAIKNQYQIESVAHLSCITSTKEDVLTECRALKEHHVDNILALRGDYPAGEEEKYRE
KEMEFHYASELNQFIKENFGDTFCLSGACYPEIHQEADCFQDDLQALKKKVDAGAEYLIT
QIFFDNNYYYRLIKEARKIGITVPILAGIMPVTNAKSLLRTAKLCGCSIPFQLSTMIETY
YNYPEAMKEIGINYAAHQIIDLITNGVDGIHIYTMNRPEIAQRIFANIPTVLKELNHD
>A0A354FCR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MKVGSNLEKVLASGQFCCTGEIGPVTYSSFDNIDKHAEEMRGKVDSVNFTDNQTAVVRLS
SWAASLRLLQLGMEPNLQMVCRDRNRLAMQSDFLGAYAHGIRNVLCLTGDHQAFGNHPGC
KGVFDLDSVQLIYMLKRLRDDGCFECGAECKVAPKFFIGCAENPFGDPFEFRPIRLEKKV
NAGADFVQTQCILDMERFERFMELCVERGLHDRAYITAGIMPVKSPKMARYMQHGVPGMI
VSEEFCQRLEKAEDAKAEAVQLSVEYINHCQEMKGVAGVHVMAVAWESIVP
>A0A4Q7JNW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pochonia chlamydosporia 123|TrEMBL
MDKITDKIAALPAGREYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSKRLIDKALDDAKALGIRNILALRGDPPRKEE
YRDASDPEDDGQEDFTWAIDLVQYIRKKHGDHFCIGVAAYPEGHSDESHPLGQSLEHDLP
YLVDKVQAGADFIMTQLFFDINAYDHFEKTLREHPSGAFKTIPILPGLMPIQSYQMIKRT
TKLSHAKMPTAIMDRLDAVKGDDEKVKLVGVDVISELIDQIRTIKNRTPGRRGFHFYTLN
LEKAVSFIVERTGLIPDESENDEAVIDDGALSPPAIQVNGTRTSTHSRTSRRHSSVGSDP
HNRVIVGGRPATHPEWEATGQEAGVPAESINSRANTLAISEGEGVLGREATWDDFPNGRF
GDSRSPAYGEIDGYGVSLHMSVTQAVTLWGRPTTHEDVNNVFVKHIKGEVPSIPWSEEGL
SPESSTIQSRLMDMNTKGWLTVASQPAVNGLSSSDRTFGWGPRNGFVFQKAFAEFFLPSA
DWALLADKLKGSDYCDSVCFYAANAKGEFVSSDVTGGVSTRTVAASTNAVTWGVFPGKEI
VTPTIIEEVSFRAWSEEAFGLWGEWAKVYGRGSESEKLLSGIRSDYWLVNIIHHDFIDRE
ALWKLLLG
>A0A520MDD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR92 clade bacterium|TrEMBL
MTNSITPKVSFEFFPANTESMEKTIRRSIEKLESLNPEFISVTYGADGSTRERTFDAIAS
IQARGTVDAMPHLTCVGAQKDDIASIADEYYELGIRKIMALRGDPQGGAGATYAPTEGGF
PYAEQLVEGLAAQHDFDIYVAAYPETHPDAPSPHFDLQNLKRKFDAGASTAITQYFFNTE
SYLRFRDAAVRMGIDNPIIPGILPVTNFATLQRFSKASSITLPKWLETAFAGLDAEPETR
QLIAANIAIEQVIALQAEGVNDFHFYTLNRAELCYAVCHALGVRRANTNENNTVEAAA
>A0A292Z5E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. N23|TrEMBL
MPVSSTPPRRATVVDRLHVDRPVFSVEFFPPKDAAGEAQLWGAIRRLETLDPAFVSVTYG
AGGSSRDRTIRTTERIASDTTLVPMAHLTAVDHTRAELRHVIGSYAAAGVRNVLAVRGDP
PGDPLGEWTPHPEGLAYADELVTMVRSLGDFCVGVAAFPYGHPRSTDADTDFARLVAKIR
AGADFAITQLFLEPGGFLRLRDRLDAAGCRVPLLPGIMPLTTVRTLHRGPELSGAPLPDD
LVARLDRFSDDPVAFRAAGMDATTELCEKLLAEGVRGLHFYTLNRSPATVELVGRLGLAA
GR
>A0A0E3NP12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. WH1|TrEMBL
MLFNFREKLNSRKFLVTVEVSPPKGTRFSASLEDTCQLKGAVDALNVTDNQCSIMHMSSL
AFSKLLLDQGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDHPICGDHPGSKP
VYDLDSVQLIELVRKLDSGIDFAGKKLDGSTSFCAGAVSGIDPENILQLIKLEKKVRCGA
DFIQTQAVYDVGRFEEFTEAVNHLEVPVIAGLIPLKSLGMAEYMNKNISGIHVPEETMLR
MKDAASPIEEGLLIASETIKELTKLSRGVHIMPIGSHKNTPRLLSMAGISDKQRDPENSL
>A0A0A3JUD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ureibacillus massiliensis 4400831 = CIP 108448 = CCUG 49529|TrEMBL
MGLREALQTKVLTADGAMGTLLYSYGLDYCHEEMNLTRPELIEKIHSEYIAAGADVIQTN
TYGANAIKLARYGLESQVKEINEAAIKIAKKAVQSGDQFIIGSIGGILGVRKSDTTLNEI
LTTVREQAEILIDGQIDGILLETYYDFEELTETLKLLRTMTDIPIIAQVSMSEPGVLLNG
IKLNDALLELENIGADIVGVNCRLGPYHTIQALETVELPKKAYLSAYPNASLLDIEEGRV
IYESEVDYFARAALELRNQGVRLIGGCCGTTPKHIEAVKKQLSNLKPIEQKRTKPEKEVL
IREPEPRNTEPLHEKVKRERSVIIELDTPRHLEVDAFVEGAKVLYKEGADIIMMADNSLA
SPRVSNIAMGAILKQHGIRSMPHITCRDRNLIGLQSHLMGLNALELHDILAVTGDPTKVG
DFPGATSVYDVSSMELITLIKQLNEGISFSGKALRKKANFSVAAAFNPNVRVLDRAVSRL
EKKIEHGADYFISQPVYSKEKIVEIYEATRELEAPIYIGIMPLTSFRSAEFLHHEVPGIK
LSDEVLERMKACDGDKDREAEEGIAIAKELLDTATQYFNGIYLITPFLRYDFTLQLMQYI
KQLDEETKGVKVNG
>A0A7Y7YEV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas gingeri|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLEQYKSAGIQRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGAHFHIEVAAYPEMHPQARNFEDDIQHFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7Y3JP59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. ID1715|TrEMBL
MTLSLAQMEEARRALDAPLFADLSGDVGVSFEFFPPKSEKMEAQLWDAIQTLAPLGPRFV
SVTYGAGGSTRERTHSTVARIQRETSLSAAAHLTCVEATREEIDAVAEEYWAAGVRHIVA
LRGDPPVMGAKFAAHPQGYANAADLVAGLKRLHPFEISVAAYPELHPDSGTQAVDLDNLK
RKLDAGASRAITQFFFSPDCFFRFRDAAAAAGIDAEIVPGILPVSNVAQTRKFAGLCGAE
IPGWMDRLFEGLDDHPGARQLVAATLAAEMCRKLYAGGVRNFHFYTLNRAELAYAICHLL
GLRPVATIQEQAA
>C2XZ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTSIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPNFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRKRMDGHETKEAAIEEGIHISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1B1YVJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Immundisolibacter cernigliae|TrEMBL
MSSARSFSFEFFPPRSDEAAARLAEARRALLPLRPGYVSVTFGAGGSTRDLTLDTVATLQ
RQDGVPVAPHISCVGATAASLRELLDAYRALGIRRLVALRGDLPSGMGDTPGEFRYASDL
VAFIRRQTGDWFHLEVAAYPEVHPQARSARADLDAFVRKVQAGANGAITQYFFNADAYFR
FCDAAAAAGVAVPIIPGVMPITNYTQLARFSAACGAEIPRWLARRLEDYGDDLDGLRAFG
LDVTLALCRRLLEGGAPGIHFYTLNRAEPTATLWQALGLGQPAHQRA
>A0A4Z1H2E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrytis hyacinthi|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRAIDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDGFEQKLRDHPSGAFKDIPIIPGMMPIQSYQMI
KRTTKLSHAKLPSTIITRLDAVRGDDEMVKKVGVDILSEMVEHLKSTKSKYSGPRGFHFY
TLNLEKAVSFILERTELIPDAETVAALEPEFVPTIPDIADLMSIHSGSHKRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGPKNGFVFQKAFVELFL
PTADWKTLHAKLTSPELRDTVSFYASNSKGDFISSDEAVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSQTRKIIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLN
>A0A2S8W781|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. MYb31|TrEMBL
MASPASLAEARALLLSPLGPVARAGSNRNAVNVSFEFFPPKSDEAEANLWSAIRRLEPLN
PAFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRADVDEVIEGYKAIGVD
HIVALRGDPPGGDGIGGAYVPRTDGYANATELSQAINRVGGFDITVGAYPERHPESPSID
HDIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGIMPVSNFKGLSRM
SAACGASIPDWLAAHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELV
YAICRVLGVRETKAVA
>A0A1I1PP95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algibacter pectinivorans|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPKKGKNIQDLYNNIDPLMEFKPPFIDVTTSREEYVYID
KGNGLLDKRITRMRPGTVGICASIMHKYKVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKDEPYFKPVKGGNAYASELVEQIATLNRGQYLHDDVVVEHNSDFCIGVAGY
PEKHMEAPSLVTDLRRLKAKVDAGADYVVTQMFFDNNKYFEFVDKAREMGINVPIIPGIK
PIAVKRHLQILPQVFKIDLPQDLIDAVEGCKDNQAVRQVGVEFAIQQSKELREAGVPVLH
YYSMGKSDNVKAIAQALF
>A0A496QXJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MKNSKAGSRLEKLLDRGEFVVTAELGPPKSVDREVIDSKVEALRDAVDAVNITDNQTAIV
RVSSISTGIYVAEKGLEPIFQVTCRDRNRLAIQADLLGACLNGLKNVLCLTGDHQSFGNH
PQAKQVYDIDSIQLIKMVKDMRDEKIFQCGEEIRNSKKAEIREPRFLIGAAANPFADPLE
WRVNRLEKKVNAGVDFIQTQCIYDMERFEQWMEEVVSRGLHEKVKILAGVTPIRSLGMLR
YMRDSVAGVRIPDSVIKRFEDAENAREEGINFCVEQIKRFRKMKGVAGVHIMAIEWENAV
RGIVESADLLPRPNGV
>A0A1G8J6R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. OV700|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPEFCSVTYGAGGSTHQGTFGAVREILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFLYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDE
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TELCARLRDGGAPALHFYTMNQSTATLAVLERLG
>A0A4S0NE57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M3A.F.Ca.ET.201.01.1.1|TrEMBL
MNFSQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDPIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A0N0J744|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. AAP43|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKVF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VQNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDEAKFLSGRKLSTPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGFHEKCFILAGV
GPLASAKTAKWIRSNVPGIHIPDHVIARLEGAADQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGVLKGRQPWKREHARADDIAAKRMHEIGTDPVQDQQELAGRAA
HPQPH
>A0A6S7DPN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter pulmonis|TrEMBL
MSDSISPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLREILLAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIRQETGDWFHIEVAAYPEMPPQAASVSADMDHFVAKVNAGADAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLSEFGDDKASIRAF
GVDVVTELCQNLLDNGAPGLHFYTLNHAEAPMAVWKELSR
>A0A7Z0Q9B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. 323S2|TrEMBL
MTDLTTPARAEGQDGHLQNGHLSSKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFV
SVTYGAGGSTRERTHSTITRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVG
LRGDPAGGIGTPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDT
LKAKVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAG
TSVPDWLAEKFDGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISH
LLGIRAKSAQKAA
>A0A6M8EI48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoarcobacter acticola|TrEMBL
MFETLIQKLQEDRFLTLETTPQHEPSMHNIIERIKKFKLQDRVDGFSCTDNPLAKLKYNA
LFASLKLQMEFKKPVIATMSMRDRNKIALQSDLMGANDFDVRAILALTGDPAKMSDQPHS
KGVFESNSLMLLKIIKSFNYGMDYSGHPFKIEPKQIFPFAVVNSYAKNFSSLERKMHQKI
QNGALGIISQPVFDIENAKKLLESFNIAKDGVEGDKKKAQLIFGLFPVTKLRTALFLSAQ
VPGIHVPQFWIDALESAHSISEEEEYKVGMKLSSDLFKEINKLHPKIHLMTANRFDVANE
IIS
>A0A6I7Y2P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. col6|TrEMBL
MALGTPSTRTDHARTVREMLATGATSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVKATQDIAAESTLTPVAHLTAVDHSVAQLRNMVGQFADVGIRNILALR
GDPPGDPMGPWVEHPQGVKYAADLVRLIKEAGDFCVGVAAFPERHPRSEDWDTDIRHFVD
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCETPIIPEVMPVTNVRQLERFSQLSDAKL
PDDLKERILAAKDDPAAVRSIGIDFATRFSAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A8F8K965|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. AB2/73|TrEMBL
MSHIDENPLGVHLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLHEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEVIKRIEDAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRTDALVAERLHQISEGREENQQAMAEIAA
HHTPPQAH
>A0A2R6B2Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marsarchaeota G1 archaeon OSP_B|TrEMBL
MKILYEVTPPSKRATRHELDYVVKNASSCGANEVDVTDSPTGESHSSSVAACVYIKTKYS
LPVMCHIRTRDITLNALRAMVRACAVWEIEHILLVMGEGGENTGLTPTHALRVIREEKLL
EGSTTKVGFVLQKGKSVEKKIRAKPDFLYTSPLTSVEELEWAVELSRSQNFELFPSLIVP
SKKNEVILKRIGLQALSAERALTLATHALRLTSNLVVISPADPDEGFSFLKRLNRNGL
>L1N8R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp. oral taxon 138 str. F0429|TrEMBL
MSQERMAIREHLKKEPLVFDGGMGTYYAQKTHTRGKGVELANIETPRVVEEIHTEYLRAG
AQAIKTNTFAANCSVYQGDTALVERILRSGWEIAARAAEPFDAYVFADIGPVTGLPPADI
LDEYRFLVDTFLAGGARHFLFETNSSTEGLVETAAHIKQVCPEAFVLTSFSAFPGGYTRD
GFFVEELIRTVTESGYIDAVGFNCVSGVQSMKELVHLLGTCTLPLSLMPNAGHPIVIDGR
TFYESAPDYFGDGLAALVREGVSIVGGCCGTTPEHIRALCLALADSGRVSTEHMGQAEHT
SLEASHSAFFEALKTGGTPIAVELDPPEVGNADKFMAGARELMEAGVHAITIADNPIARA
RMDAAMLAGRVQRSLGLEPIPHMTCRDRNLNAIKSILLGLSAEGVHNLIAITGDPIPTAE
RDEVKSVYQFNSRKLSAFIKSLGERGDVVPFHVFGALNVNSIHFPSQLGLAKKKMEAGMT
GFFTQPVLSSRAKENLRTARDTLPGALILGGIMPVVSERNARFMESEISGIHVEQRIIDA
YHGLDREAAEELAVQLSLETAKDIEPYIDGYYIITPFARTALVARIVKELRRK
>A0A5K7YCZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina alkanivorans|TrEMBL
MLRVFQTDISDPAQFVVTLELVPGRESTGRSVDTVMGIAKDAFADGRISAVSITDNPGGN
PSLSPDAIGYRIFSIGMDVIVHFTCRDMNRVGMESRALQLAMMGMKNILALTGDYSGKGF
GGQGAPVFDLDSVNLQIMLMLISRRMAAAGDPDGFFTGCAVSPFKHTEGECVAQYAKMSR
KVAAGAQFIITQLGYDARKFHELIGIQRHMSLQVPTLGSVYVLTPNAARIMNRGRVPGAV
VSDPLLGAVQREWQDRRQGKQAAIERAARLGVVMQGLGYRGIHLGGIHHDFSAVGMILDR
MEQIREHWQAFLPQFNFPHPGGFYAFREKPPQAATVPRFGLHPRPVPVLDRALYPLMRHS
HGLFFNFDSPAAPFFKTICKTLDSGLVGRLFMHLAEHPVKRMLLGCQQCGDCAIQHVGFL
CPESGCPKHTRNGACGGSRDGMCEVNPDRQCVWYRAHSRLAAHGNIKSLCEGCVPPRMWE
LNHTSSWLNFHLGRDHQSNGSEIAGFCRQATCRLLAEE
>A0A8J3H8W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodonghicola xiamenensis|TrEMBL
MSAATQKVPEVSFEFFPPQTLEASFRLWDTMQTLAPLGPRFVSVTYGAGGTTRDLTREAV
AALHKSSGLKVAAHLTCVNATKEETLTIAEDFAKAGVTEIVALRGDPPKGEGKFTPYPGG
FANSVELIEALAATGQFSIRVGCYPDTHPEAASAAADVDWLKRKLDAGADEALSQFFFEA
ETFFRFRDACEKAGIDGAKLTPGILPIENWKGARNFARRCGTNIPQWVEEAFDKAVRDGR
EDLLATALCTELCSDLLAGGVDRLHFYTLNRPELTRDVCHALGVAPKTGLQNVA
>A0A3Q9FUU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces luteoverticillatus|TrEMBL
MALGTASTRTDHARTVRELLASGERSYSFEFAAPRTEKGERTLWDAIRRIEAVAPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSVAELRNVIGQYADVGIRNMLALR
GDPPGDPMGEWVRHPEGVRYAAELVSLIKESGDFCVGVAAFPEMHPRSTEWESDIRHFVD
KCRAGADFAITQMFFHPEDYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFAQLSNAAF
PSELAERILAVKDDTAAVRSIGIEYATDLCARLMAEEIPGLHFITLNHSTATLEIYQNLG
LHQRS
>A0A1C3NTN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Frankia californiensis|TrEMBL
MIDEARAASEDPVFADMPTFRVGAAAGLRPLPAWKRAADFLFVQVSYSVDALLRWRDAHP
VELPVYAGVMVLASAGMARCLAATIPDIDIPDDLVQAVERDRTAGVEAACDQVLQLRDSG
AFAGVHLVPVSRYRQVATRLEDLL
>A0A1G1HP13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium RIFCSPLOW2_12_42_9|TrEMBL
MKIARLLKNKRQIFSFEFFPPKTDEGEKRLFETIENLKELGPSFVSVTYGAGGSTRDKTA
GWVIRIKNELDIEAMAHLTCTGTSCENLKRILDKLQENGIENILALRGDKPQDTNSIAQM
PQCYNHTNELIQYIHDNYDFCIGAAAFPEGHTESPSLEKDTYYLNMKSMAGAEFFITQLF
FDNRLYFDLLDRASKIGINKPIIPGIMPITSADQVERFTSLCGATIPSDLRERLHEIRND
RRAVMELGIGYATKQCQDLLSKGAPGIHFYTLNRSSATRTILKNLKS
>A0A2A9ELE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Georgenia soli|TrEMBL
MLRSNLGGVPGYPTVSFELFPPRRPELDEIVWQRVLRMAAAGPDFFSVTYGASGSSRAAS
ADLVRRLLAETHIPPIAHLTCVGATREELAQRVRDLLDSGVRDFLALRGDPPAGETEWRP
VPGGLSRSSELVALIRQVEGEYLGLRGAERGTEDDDAGVHGTGVHDGGHGPTPEPPSVVA
REVGVEPADVVSVAVAAYPAGESHGREAELEALREKQEAGADFAITQVFFDPEAYGSLVA
EARAVGIRIPILPGVIPMTDRGRLHRLSELTGVPVPATIDALLATDDEHERLRRGIDATL
ALIDRVLAAGAPGLHLYTFNHDRPALDVLEHLRARGLRNPAIVGGPEVAVGRAGRGDGTA
GTGATGRAGGGRAR
>A0A222VUY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella marina|TrEMBL
MTSVIERMRGERPVFSIEFFPPRDETDEAVMWRAIRDLEQLDPAYVSITYGAGGTSRDGT
IRSIARVATETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGEWA
RHPEGLGYAEELVALIRSLGDFCVGVSAFPYGHPRSPDLATDTKHLVRKFNAGADFGIAQ
LFFEADDFLRLRDRVAATGCDALVLPGIMPLTTPRTLAKTIELSGAKAPSALLDRLEPLK
DDPKAFRAEGLDVVTELGQRLLDEGVPSLHFYTFNRSKATRDLVGRLGLVPARA
>A0A5E7KU81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLKQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLANFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>W4G8Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces astaci|TrEMBL
MKIIDKINEKIEKKEPFYSFEYFPPKTPAGVTNLYTRMDRMALMEPLFCDMTWGAGGSTA
SMTIELCVNAQKLSGLEMLMHLTCTNMPKGSIKNALDSAKDAGIQNILALRGDPPRGQTE
FKECEGGFAYAIDLVKYIREEYGDYFCIAVAGYPEGHSDAKDLDTDILHLKEKVDAGADF
IVTQLFYDVHKYFDFVDKCRAVGINVPILPGIMPIQNYNGFVRMSSMCGHVPDAILQALE
PIKDNDEAVKDYGVELGIQMCRDLLDHGVPGLHMYTLNLERSTRLILEGLGLTATARREL
PWRPSTLAKRAGETVRPIFWANRPKSYLDRTASWDEFPNGRWGSSESPAFGDLNESYYSH
TTASVQERKAMWGESPVTYADVYETFTRYVMGAVKSLPWCDTPLHLETKSIQERLAAVNR
AGYLTINSQPRVNAAPSDDPMFGWGGPGGHVYQKAYVECFVSPENLKRIIEKCNKMKHVQ
YHAVDVNGNSYSNCGKGTTAVTWGSFPNKEILQPTIVDTDSFMAWKDEAFSLWLSMWASL
YHDESAAHALIHQIRDSFFLVSIVDNNFVNGDIWDAFDVDVTTASAAGP
>A0A0C4DPG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnaporthiopsis poae (strain ATCC 64411 / 73-15)|TrEMBL
MHIREMLAEADRTGNPSFSFEYFPPKTAQGVQNLYDRMERMYHLGPKFIDITWGAGGRIA
ELTCEMVTQAQTYFGLETCMHLTCTDMGVEKVNDALAKAYKAGCTNILALRGDPPRDKEK
WEAAQDGFHYARDLVAHIRKTYGDHFDIGVAGYPEGCDDNKDEDSLLDHLKEKVDMGASF
IVTQMFYDVENFLRWVGRVRERGITIPIIPGIMPIATYASFLRRANHMQARIPDEWIRRL
EPVKNDDAAVRVMGKELVVEMCRKILAGGIRHLHFYTMNLAQSTTMILEELSWLPSPTKP
LKQALPWKQSLGLGRRGEDVRPIFWRNRNKSYVMRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLVGTNEQNRQKFGEPRSFKDVASLFIRYVNKEIATLPWSEAPLTGEGELIKDDLLD
LNRRGLITINSQPAVNGVKSSHPVHGWGPPNGYVYQKAYLELLVHPSLFAEIKSRLHTHP
DLTYYAVTKSGDLQTNATYEGPNAVTWGVFPGKEIVQPTVVEGISFLAWKDEAFQLGMEW
ARCHEANSPSRVLIQKMMQEWYLVNIVNNDFHSPRTIFDLLKDITVPDLYKEVVVPVDHG
PEANGTNGTSVTNGTHQTARSVATAVAA
>A0A5P1ZJ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces venezuelae|TrEMBL
MALGTASVRSDRARTVREILASGGTSYSFEFYAPRTAKGEQGLWNAMRRVEAVGPSFVSV
TYGAGGSTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNVLGQYADAGIRNMLALR
GDPAGDPLGEWVEHPEGVRYAVDLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVA
KCRAGADYAITQMFFDPENYLRLRDSVAKAGCETPIIPEVMPVVNVKTLDRLPQLSNAHF
PADVKERILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A846N3F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilaceae archaeon|TrEMBL
MTIRYEANPPKITPGVDLDESISKFIEKIKLISKNCDAIHLTENVLGFERVSPLKVGKII
KKEIPELPLTVSLRVRDKTQEEIDSFVQDAISSGFSGILVLMGDPSQAGQKDSGLIPSLV
VKQLYENKINEKIDLYLSISNKPNFSKIEKKLDAHPKGFMTQVVQNLEQVETLAENLKGY
LVIPIVLYPSDKNEDSAKFLNLDLAKYKDNFGEFLSKIEQITGDVLITSPRDFTSLKEFL
ETRG
>A0A146FKQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus kawachii|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSNWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHVFVDFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A1E3C933|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter adhaerens|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYKEHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A096G811|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas thiooxydans|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPEFCSVTYGAGGSTQAGTFTMVRDIQNE
GVGAASHFSCIGATHEKVRAELNELKAMGVKRIVALRGDLPSGYGLGGEFQYASDLVAFV
RQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VRALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A825KIW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSGKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEIEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A031GQ40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium lividum|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVKRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGANAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A845AWJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parerythrobacter jejuensis|TrEMBL
MVPPLDPQHEELTAHDTPLFSGLPGDIAVSFEFFPPKSETMEAKLWDAVQELKPLDPSFV
SVTYGAGGSTRERTHKTVARIISEAQIPAAAHLTCVDASKADTQAIAEQYWEAGVRHIVA
LRGDAGEPGAAFTPHPQGYANAAELVAGLKEVADFEISVAAYPETHPDADCPQADLDNLK
RKIDAGASRAITQFFFSAETFFDFREAVAAHGIDAPVVPGILPVTNVAQARKFAGQCGAL
IPEWMDGLFEGLDERPASRQLVAATVAAELCRRLYAGGVRDFHFYTLNRADLAYAICHML
GRRPKGIAA
>A0A6C1U2J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sanguinis|TrEMBL
MYQRLTSTRLSASAPLDRLDEDVNPSAAAPRRSTRTALSFELIPPRHDADTALLDNLIAG
LAEYNPDYVSVTSSRRSDWLEGTAALIKRIAETTDLKPIAHLACTAGTRDELTEWIRTLI
DAGVRGFLALRGDLPEGETSLPEGYLPYATDLLNLIQEVQDEQAFRLAAGKLALSVACYP
SGHAESKNADMDLDVLLAKQRLGADFAITQLFFEAQDYLDFVERSRLAGVRIPLIPGIMP
MTSLRRVERMGVLSGITVPQRVTDRLSKASTPDEEYEIGMAMSAELTREILDAGTGGLHI
YTHNNLAVTRDLLSRINL
>A0A5B6ZDG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Davidia involucrata|TrEMBL
MKVIEKIRGAAVAEGGEKVVFSFEFFPPKTEDGVDNLFERMERMVAHNPTFCDITWGAGG
STADLTLEIANRMQNMVCVESMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHG
QDKFVQTQGGFACALDLVKHIRSKYGDYFGVTVAGYPEAHPDVIQSNGVATLEGYQNDLA
YLKRKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFC
KTKIPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKIMANGIKTLHLYTLNMEKSALAIL
MNLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDS
RNASYGALSDYQFMRPRARGKKVHQEWAVPLKNIDEIHEIFKKYCLGNLRSSPWSELDGL
QPETKIINEQLGSINLKGFLTVNSQPAVNGAKSDSPSVGWGGPGGYVYQKAYVEFFCSRE
KLNALVEKCKAFPSLTYMAVDKEGSWISNISQNDVNAVTWGVFPAKEVFQPTVVDPSSFM
VWKDEAFEIWSRGWAQLYPEGDPSRKLLEEVRCSYFLVSLVDNDYIHGDLFAVFKDF
>H5SL32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Chloroflexi bacterium|TrEMBL
MSSHPFLDLLDQLEAPLLADGAMGTMLHAHGISFDRCFDALNLEQPQLVLDIHRQYVQAG
ARLLLTNTFGANRYKLERHGLANQLIEINQAGVALARRAAQEGREQVFVAGDVGPLGVRV
APYGRVRVEQARLAFAEQIQVLAQAGADVIVIETMSDLNEALLAIEAVRQSCDLPLIVSL
TFTRDDRTLLGDDPASAARRLSEAGVDVIGINCSSGPAQVLRILKQMRAVAPQARFWVKP
NAGWPEQVGGRIMYPASPAYFGEYSMAFCQAGARVVGGCCGTTPAHIAAMHEALSRLPQQ
CTAPQIEWTPPREEITPIEVPPSQLAQKLADGRFVISVEMEPPRGLATEKLVAAASLLQE
AGADVINVSDTPMARMRMSAWAVCEVIQRQVGIETTLHFPTRGRNLLRVQGDLLAAHALG
IRNIFVVMGDPTAIGDYPEATDNYDLVPSGLIKLIKQGFNLGVDHSGTSIGQPTRFFVGG
ALNLTAAEPEQEIKNLRRKIKAGADFFITQPIYRPEDGERFLEEYEKRHGALEKPILIGI
LPLVSLRHARFLHHEVPGISIPQEVQDRLERAGDHAAQVGVELAIELIEKLKSWAQGIYL
MPQFKRFDLIAEIIEAVKTTVKA
>A0A377QJ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium lividum|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVNRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A2B9F644|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0R2HJD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pediococcus damnosus|TrEMBL
MKLTEIFKHKTVFSFEVFPPHGEAPVDKIRKTLTNLEHIHPDFISVTLGAGGIGAQNQTV
GIANFIQNDLNIPAVAHIPGLYQSKEDVRKLLAELSGHHISNILALRGDKIAGRTPVGDF
NHANELVSFIKEQPGDFQLMGACYPQCHQEAANLIEDIANLKRKVDAGADHLISQLFYEN
QCFYDFMDQTRSAGISVPIEAGIMPVTNKSQIERMAKISGKPLPEKFAAILNHYADNKEA
LRDAGIAYAIDQIVDLVAHGVDGIHLYTMNHSKVAQRIWDATASLFKDSEEKPSVHL
>A0A174DII6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides distasonis|TrEMBL
MKVIDLIRNSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQKPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNDKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A1W6WTK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A5F0HJP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFDLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPKKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKISKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A4Y8QIM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sumterensis|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTTELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSFGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNSKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGV
GPMASAKTAKWIRSNVPGIHIPDSVIKRLEGAEDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRKPWKREPNPVDQLVAERIEMARDGHEQDQQKLAGQAA
QQPL
>A0A8G0KAM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. animalis|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSLEKPDYISVTYGAGGNTKGRTV
EIADRIKRQNGLESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEKGD
FNYARELIEYIHKKKGDKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRHE
>A0A2U4AZR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tursiops truncatus|TrEMBL
MVNEPRGHGGPSPRWEGSSSGSESSKDSSRCSTPVLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKRLGLKNILALRGDPIGDQWEEEDGGFNYAVDLVKH
IRSEFGDYFDVCVAGYPKGHPDAESFEAGLKHLKEKVAAGADFIITQLFFEADTFFRFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDDAIRNYGIEQ
ALSLCRELLASGSVPGLHFYTLNREVATTEVLKRLGMWIEDPRRPLPWAISAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFEVFVHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGDNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWVEQWGKLYEE
GSPSRTIIQHIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLSGPPQSKRETEAP
>A0A3Q9CMF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter sakazakii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRSIARDYWNNGIRHIVALRGD
LPAGSGKPEMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPALELKT
A
>A0A4S8S3N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSIANS
APQNRVVIDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVE
FFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLL
EA
>A0A8B3VPT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae|TrEMBL
MQINYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTY
GANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGD
EPAGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHV
ITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYE
GLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A3Q2WWY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haplochromis burtoni|TrEMBL
MVNQVQRGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQSKEKITGYLAKAKHLGLKNIMALRGDPIGEDWEEEEDGFNYAID
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNY
GIQQAVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELQNEESVFEVFTCYITAQPNRCGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVNGRNLTNAPEMQPNAVTWGIFAGREIVQPTVVDPVSFMYWKDEAFALWIEQWGK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPELHSEETV
>A0A2E6MKE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MKSLLQDNRVHVFDGAMGTLLYSRGVFVNVCYDELNLSRPELVRGIHEEYINAGAEILET
NTFGANPVKLSSFGLEDRTEEINEQAARLAVEASSKAEVSELTKANVPEYFSGGTVAVAG
ALGPLGIRIEPWGPTSLDEAEAYFARQVDGLLEGGVDGFVLETFSDISELQCALRAIRVA
CELPVIAQMTVGPDGKTSFGTEPAHLAQAMEDSGADVIGLNCSVGPAVMLDALEDMAEVT
QLPLSAQPNAGLPRKVRDRKIYLASPEYMAQYARRMIDVGVRFVGGCCGTTPDHTRRMRD
SVAALQPKHPVVTIRDRANSSHSVINSVPLEGRSAWGRKLARGEQIASVEIIPPHSWDAS
AVTSPARELKVSGVDAVSIVESPRSRSRMGALSAALIVEREVGIETIVHYTCRDKNMLGM
ISDLLGAAAAGIRNVLVVSGDPPVMGPYPDTTVVFDIDSIGLTNVVQGLNQGIDPGGNTI
GAPTEFVQGVAINHGAVDQERERSRFKYKIEAGANFAITQPVFSPEALEQFLDATTPEIP
IVAGIWPLTTLRNVEFLANEVPGVHVPTELVDRMKRAQLSGADAALEEGIAIALEMINAT
QGFVQGFHLTAPNRKVQVALKVLRESGILATA
>A0A6B1BGH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MRFLDYFTGNQPVISFEIYPPQTQGGMRALKARVIPNLLKLNPSYMTVTYGAGGSTRAKT
LEIASLIQNEFGLTAACHLTCVGSSRTDIDDILKAIRTEGIRNIVALRGDPPRGEDTFVP
AKDGFAYGNELVAHIRSTEPKDDGFGLAVAGYPEKHLEAPDFDTDIENLKRKVESGGDII
ITQLFYNNDYFFRFVDRVRAANITAPVVPGLMPILAAGQIQRIASLCGSEIPEDLQDQLK
GAVDDEDKAMRIGIDQCIGQATELLEQGVPGIHFYVLNKSTHMRRIISALPL
>A0A1S2KVT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobacillus isosaccharinicus|TrEMBL
MSFLQDMKTKTLIGDGAIGTFLYLKGLDRCFEELNLSDPTKVKEVHEAYLQAGSQIIQTN
TYAANKIKLTRHGLENKVAIINKAAVNCANEVVTNKDAYVIGTMGGIRGFQKRSHSMEEI
VYSFEEQMNSLLECDIDGILLETFYDFEELSTCLMLARKKTDLPIISHVSLDEVGVLHGG
IPLKDALSALEDLGADVVGMNCRMGPFHMLQSFEEVPLLKRAFLSAYPNASLPDYKDGRL
VYQTNPKYFGDSAKAFVEQGIRLIGGCCGTTPDHIKAVADAVRNQKPVEEKQVKVKQKQS
IVVFHKEQQESLPSIVQRRKSVIVELDPPKKLNTDVFVEGSKKLKEAGVDAVTLADNSLA
SPRICNLSLASIIKKEYNVRPLVHITCRDRNLIGLQSHLMGLHTLGINQLLAVTGDPTKI
GDFPGATSVYDLASFDLIRLMKQMNNGVSFSGKDLGARTNFSVGAAFNPNGNHLEQMVRR
MEKKLEYGADYFLSQPVFSIEQVAKIYEVTKHIKAPIYLGVMPLTSSKNAEFLHNEVPGI
KLTEETRERMMRVSGDQEASHYEGIQIAKELIDEVHRYFNGLYLITPFLRYEMTVELTKY
WQWKSKLIQPEKLSN
>A0A8C8FYF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
INSSGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTESGDHWFSLEFFPPRTASG
AVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCN
QTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKHIRCEFDDYFDI
CVAGYPTGHPEADSYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVRDCRAIGITCPI
LPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIRNYGIEQTVGMCRVLLES
GNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPK
SYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEELTSEQSVY
EVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMMDELDKVNRRGVLTINSQPTINGKP
SDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPRVNYHIVNVHGQNTTNAH
DMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAELYDDESPSRMIIKYI
HDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPTEQPVEQPAEESPVEDQSPK
>A0A2G4HYN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSREPKRLKDVLAQGQFAVTIEYNPPKGTNISSVLDNAKQLVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQMTCRDRNRIAMQSDLMGASMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVLGLNNGLDMAGNKLDGATDFTIGAAVTPEADPLGPMLAKFEVKV
KAGAQFFQTQAIYHPEQFAAFMKAVRPFKVKVLAGILVLRNAKMAEFMNANIPGVAVPQE
MIDELRAAGPGRAEDVGVDIAVRTIKAVRPYCDGVHIMAIKATHRLSEILTKAEVG
>A0A2G5FWQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sediminis|TrEMBL
MSQQRRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTVNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNLEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRVFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLSIWNNLKLPR
>A0A1G6JBD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas chengduensis|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRVFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLQR
>A0A4Z8XST9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Bareilly|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J5ERL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia paludis|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLQPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGADV
VTGLCQRLVDAGVPGLHFYTLNTAAATRTICERLAG
>A0A6P2GI19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia anthina|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTDLCRRLIDAGVPGLHFYTLNAASATRTICDRLAG
>A0A0S7E2M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus lentulus|TrEMBL
MEKITDKIAALPPNENYFSLEFFPPKTQMGFSNLTARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCLGVAAYPEGHPVDSYQDVQDPVRDLPYL
VEKTLAGADFIMTQLTYDIEAYTKFEEMLRNHESGAFKTIPIIPGLMPIHSYKILTRTTK
LSHVKIPPQIMASLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLNLEKT
VSFIIERCGLIPDYPEDTNAVVDDDYTTAPTGAQNRSLSRRRASSVNSHPHNRVIVDRLQ
VPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQISEGQGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVSGAVARRIWGYPVSREDISALFRRHVSGDLYIVPWSEGGAEENSS
GLNAETEVIRPELLKLIDSKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFF
CPSKDFQTVLKPLFAKHGHEKLAWFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWG
VFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRVYPRGTPTERLLEEVKNDVWLVCVVG
QDFGAGTENGSEEEQQETKWMWNVLINSQ
>A0A1S1P435|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum extorquens|TrEMBL
MPNASQHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVDATKEEIDGVVQSYWDAGVRHIVALRGDPAEGVG
HSYRPHPGGYAQTCDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIEALKAKVDAGADQ
AITQFFFDNEIYLRYRDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLENDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
PAVKPEAKAA
>Q2Y5Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)|TrEMBL
MESQKKFVPTFSFEFFPPQTAEGIEKLRATRSQLAQLKPKFFSVTFGAGGSTRDRTLETV
LEIQAEGLIAAPHLSCIGATRENIRAMLEQYRSSGIRHLIALRGDLPSGMAQGGEFRYAN
ELVAFIRREYGNAFHIDVASYPEYHPQARTAQEDLRNFKRKIEAGADSAITQYFYNADAY
FDFVDSCEAMGINIPVVPGIMPINRFSQLARFSDTCGAEIPRWIRKRLEGYGDDTASIRA
FGLDVVTDLCARLLNAGAPGLHFYTLNSAGLTTTVWQRLGL
>A0A0T6P5R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas veronii|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A2A4SPW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichales bacterium|TrEMBL
MENDQRTISFEFFPPKNEQAAEKLAQTSATLAELEPEFFSVTFGAGGSTRDNTLECVSSI
NSATGIEVAPHLSCIGSTQQSISELLEIYKQQGIKRIVALRGDMPSGMRDPGEINYANEL
VEFIRKTTGDHFHIEVAAYPEFHPQARSAQEDVANFKRKVDAGADSALTQYFFNADAYFR
FLDDCSAAGIDIPIVPGIMPITNYIQLARFSDACGAEIPRWIRQRLEGFGDDMESLRAFG
TDIMTELCATLLEGDAPGLHFYTMNQTRATLAIWQQLQG
>A0A3D8V9S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter soli|TrEMBL
MPTPISFEFYPPKTDEQRAQLDKTAAKLKSQKPEYVSCTFGAGGSTLSYTPETVERLHRE
HGLDAAPHLSCVGGTREELGELLERYKAMGCRRIVALRGDLPSGMGHTGDFRYATELVEF
IRREHDGYFHIEVGCYPECHPQSDDALADLRHFKAKVDAGADGAITQYFYNADAYFRFVD
DARKLGVDIPIVPGIMPISNFSQLRRFSDACGAEIPRWIGKRMQAYGDDVEAIRDFAADF
VADMCRRLIDGGAPGLHFYTLNLTKPTLSVLARIR
>A0A285F9D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus euhalobius|TrEMBL
MSLKTNVTYYPAMPSAFKEKLLSDEFIVTSEISPPKGVDVSSVFEEAGLVRDYVDAFNVT
DNQRAVMRMSPLAMGHLLKERGLDVIMQFTCRDRNRLALQSDLLGAYAMGMENVCIMSGD
YPTKGDNPGAKPVYDLDSVQLLGAMNQLEGGYDIAGNPLESAPSFTKGAVCNTEPDQPLQ
LMKLEKKAHMGIDFFQTQAVYDIGHFETFMEGISHMEVPVLAGLIPLKSAHMARFMNEKI
PGIRVGDELIARMESSTDPAEEGLLICAEQIRELKKVCRGIHLMPIGHYRHITALFEMAG
LHEKH
>A0A179U9H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomyces gilchristii (strain SLH14081)|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDTALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDDQDDPELLMEHLKEKVDAGGTF
IITQMFYDVDNFLTWVERCRQKGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEAL
EPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQATKMILDELGLIPSHKTP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSLKELSEIFIRFLNGSLDRLPWSEGAVTEETEIIKSDLLD
LNRKGFLTINSQPAIDGMPSSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNS
DLTYYCVNKKGELKTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHAPSSLSRRLIEQVMDTWYLVNIVNNDFHKTHDIFNLFKDLKVENLDTEIEPIALAAE
SVDIAQQNGQLPQTEVNDSCTEATKSMEERNSN
>A0A3B9QY46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPPVTGDPGQPLAILEGHVSAGRLERVLRSGKFAVTAEIAPPDAADAEAVYERASVFDGC
VDAINATDGSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVTN
ILCLTGDGVQAGDQPDAKPVFDFDCISLLQTVTAMRDEGEFLSGRKLTTPPRVFLGAAAN
PFGPPLDYRPIRLEKKINAGAQFVQTQYCFDLVRLREYMSRVRDMGLTERCYILVGVGPM
PSARTASWIRDNVPGVHIPDAVIKRLLGAENQKEEGVRICVEMIQAVREIEGVHGVHIMA
YKQEERVRDIVEESGVLEGRIPWYPGVSNDQQGQQT
>A0A6P3QET7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pteropus vampyrus|TrEMBL
MVNEPGGHGSLNPRSEGSGSGGESSKDSSRCSTPGLDPERHERLKEKMRRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKRLGLKNILALRGDPIGDQWEEEEGGFRHAADLVKH
IRSEFGDYFDICVAGYPTGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQMKDVIEPIKDNDAAIRNYGIEQ
AVSLCQKLLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRLLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELASEESVFEVFVRYLSGEPNQKGCKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNVNGLPSSDPVVGWGPSGGYVFQKAYLEFFASRETVHALLRVLRKYALRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDE
ESPSRIIIQYIHDNYFLVNLVDNDFPLDNCLWQVLEDTFELLNTPSSE
>A0A1M7IKK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morganella morganii|TrEMBL
MSFLHIDQHEALNQNLAELAGRVAVSFEFFPPGTPEMEKTLWQSIERLSVLKPKFVSVTY
GANSGERDRTHSVIKSIKEKTGLIAVPHLTCIDATRDELKTIAKDYWDNGIRHIVALRGD
LPDSSSKPDMYAADLVGLLKSVADFDISVAAYPEVHPEARSAQSDLINLKKKIDAGADRA
ITQFFFDVSTYLRFRDRCAAAGIDVEIVPGILPVSNFKQLQRFAGMTNVRIPGWLGTMFE
GLDDDPESRKLVGASVAMEMVKLLSREGVKDFHFYTLNRAELTYAICHTLGVRPAACVA
>A0A818M4L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MEFTLGDNQTVPGDCKMHAHETHLESIHNLNRLKRIESEGANIAGKICSLQSAKYVSLTE
KISKRIADNDRWFSLEFFPPRTPSGAANLIGCFDRMAAGRPLFCDITWHPAGDPAGDKET
SSMMIANTMLNYCGIDTMLHITCYGAKKAAMLEYLYKAKDCGIRSLLALRGDPHVGEEWN
PAKSDFRYALDLVKFIRQHFGDYFVICVAGYPQGHPDSTSYEDDLDYLKEKIDCGADFII
TQLFFQAETFIKFESDCRSIGIKCPIIPGILPIQGYASLRNIVRLAKLDVPKEILACIEP
IKDNDEAIRNFGVQACLDLCCALLDSGKVNGLHFYTLNREFATIEILKKLGLWLDEQSLR
ALPWKKTSFSHARSQENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGISSAPSFGVLTDYH
LFYMKIDATRDELLDEWGRELTCEQDVWKMFACYIGGEKNSIDKVVRRFPWTDEELSAET
TLIQKNLVEFNKRGILTINSQPAVNGKSSSDPVVGWGTPNGYVYQKAYLEFFTSAENIPA
LRSVLKTFPGVNYHFVNKSGEVNETNTDDEQPIAVTWGVFAGKEIVQPTVVDPVSFMIWK
DEAFSLWTERWGKLYEPESRSHAIIEKIANTYFLVDLVDNDYPQGSCLWTILDSMFEYQK
LPKKNVEP
>A0A6A7JXX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus delbrueckii|TrEMBL
MSLTALFKNKTVFSLEVVPPKKDSPKEAILPTLQQLQSINPDFISVTSGAGGSDHYTGTV
QIADLIQNQLNIPAVAHVPGLYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDF
NHANDLVAFVHQNRPDFSIASACYPNCHPEATGFVDDIAHLRTKVDAGADYLISQLFFDN
QAFYDFQEKAEIAGIHVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILNRYQNSKEA
MREAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHR
S
>A0A6D1VVF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylacidiphilum fumariolicum|TrEMBL
MATLIDRLNESLLIGDGALGTYLYSLGIPRGYCIEELSLSHPDLLEKVHRDYIDAGAKII
RTNTAESNAYHLSFFKLEKKLKEIVSRSVQLAKKALGSREGWIAGTVGPIWTKPTESPID
MATRQSLYEELIASLIEEGVDLLFFETFTELPELLLVLDIARKKGAEKLFAFIASFEEGK
LSSGETLGEAFSKLRLAGATLVGINGACGVQASIHLLEEIELKAGDFLGAYPNAGKPEFY
DGTFTYSASPSYFGENVARFAEEGVCLLGGDYGTEPAHIAAMAQRAATIKPLKEKPPKRR
PRYLVSEQEVLPQIEPSLLDLLALKPVFMVEYDSPKTLAIGKFLEGVKAIEKAGADAITL
ADNSLAILRISNFAAAIHVRRVSKMIPILHVACRDRNLLGLQSELMGLGTLGFRHILALT
GDPAKSGDHPGATSVYDLNSVGLIRLLASLNRGFNAAGKDLKGKTDFIIGCAFNPNTTQF
EAQVKKLEAKLAAGAQFVMTQPVFDIQLIKKTYNYLKPLGIPVFIGLMPLLNYRNAEFLH
NEVPGISIPEAVREKLKALDGEKATELGVGFAQLLGEEILSLFKCVYLITPFLRYDISVR
LLELLYSRKKS
>A0A028Z408|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus haemolyticus|TrEMBL
MSRLLNQLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVESIHRSYIEAGADIIQT
NTYGANFEKLRRFGLEHKVKDIHKAAVAIAKRAARPDTFILGTVGGFRSLQQEELPLSTI
QYHAENQIDTLVEEGVDGLLFETYYDLEELTNIVTTTRRKYDIPIIAQLTASNTNYLVDG
TEINKALQQLVACGANVVGLNCHHGPHHMQRSFSHIELPETAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPQHIAYIKSSVKDLKPVKNKNVIPINRQT
NRAVTHTYKHNLTTKVKNGPTVIVELDTPKHLDTDLFFENIGKLDEANIDAVTLADNSLA
TVRVSNIAAASIIRQRYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMNYFITQPVYSKEKIKEVYEATKHLNVPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLSQFKAVKDDKEKTKALSLRLSKELIDTVHEYFNGLYIITPFQRIDYSLELAAY
SKAITQNKEAIS
>A0A072HQ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio parahaemolyticus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDATRSELIEIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRVAVEA
>A0A6L6DVJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARISDLLAAGRTFSFEFSPPKSAAGSMSLGRTIAELEPLAPSFVSVTYGAGGSTREHTR
DTVLWVGKETNIPPMAHLTCVGHTKAEISDIISTYAGAGIENVLALAGDAPKDPADARPS
DYMYAIDLIEHLHEIGDLCIGVAAHPEGHPRSPDMATDRRHLADKLRVADFATTQFFFDI
EHYVSLVNDLADLGVTKPVVPGIMPVTNIAQVERMAELSGAAFPQWLRERLESGTTAEDV
RRIGVEAATELCAALLEAGAPGLHFYTLNKSTATREIYAQLGLPVA
>A0A6I3EYU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTPCGSSSPAVRQNCPTSLDDMSSSLHHLIADARYEVIPMKNLETQLEHIPAGASVSVTC
SPAKGQQPTLDLTSRLADLGHMAVPHISARLCPDEAEVKRLAEFCRSHGIKEVFLIAGDP
EQPAGKYDGVVSFLRDFLSCDHGLQRIGVTAYPDGHAIIPAQVVHEALHAKQELLKDAGV
AGFASTQMCFDLTQWTTWAAAERAAGFDLPLHIGVPGVIDRAKLFTMGMRLGIGNSMRFV
KKNGGVLGRLFKPGGYDPNKLIIPLSKRADELNIEGLHLFTFNNVQATAEWQRKMLNRFG
G
>A0A484UYS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|plant metagenome|TrEMBL
MISLDTEKAAISLEFFPPRDLAAQERLVRTAKQLLAVQPRYVSVTFGAGGSTRDGTSGTV
RTLRNLGCDAAPHLSCIGASRDELRQILQGYRDEGVRRVVALRGDLPSGMGGDAGELRYA
ADLVAFIRAEFGDAFHVEVAAYPEMHPQAESPSADLRHFADKVAAGADSAITQYFFNADA
YFDFLDRTQALGVSVPIVPGIMPITNNTQLTRFSQMCGAEIPRWIRLRLAEFGDDKASLR
AFGVDVVSELCQTLLDNGAPGLHFYTLNSADAPLAIWRQLGLERAAA
>A0A426WN35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Java|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4R0EP91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter terrae|TrEMBL
MTKRVPISFEFFPTKTDVGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSKGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFIIEVAAYPEMHPQAESFDQDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVIDLGLA
>A0A6I3GTC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAKRTSYSFEFFPPKDAEGEARLWAAMTGLEALHPDFISVTYGAGGSTRDRTIAITSHIT
ERTKIPTVAHLTCVGSTKTELIEILGKYREAGITSILALRGDPVGGPSAPWSTTPGGFDH
ADQLVELASELGGFSIGVAAFPDGHPASGGDFEKDIDVLIRKESLGATFATTQFFFEAQR
WRALVDRLSARGSNLPVIAGILPVTNVKQLSRMSELGGTAIPEAMMKRFLAVESDPEAVR
ALGVEIATELCQKLLAEGVPGIHFYTMNSSTATREIYENLGVSR
>A0A191W6U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio anguillarum|TrEMBL
MGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSAQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASRDELIQIADDYWHNGIQNIVALRGD
IPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQSDLVNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFN
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A6I3GAK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTEGFSIAKALTAAAPTLSFEFFPPKDEAGANSLRNSIEELMTLSPDFVSVTYGAMGSNQ
DSSVAIVEQLSKIVATVAHLTCIGASTSGIQNLLMRYQSAGVAAILALRGDKPKGYDEQP
AGDFTYASDLVRQVKQFTSFEVGVAAFPEKHPESHSLADDIRILKMKQDTGASFAMTQLF
FDVEAYSQLVSSARAEGVTIPIIPGVMPFENARQVLRMAQMSGATVPPELDLKLSQAFSE
EAARTIGMDFSVHLVQDLLAAGAPGIHIFTLNQHRATLELANSANLA
>A0A6I3BEH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MMARSTFSFEFFPPKDAEGEARLWSAMDSLKSTAPDFISVTYGAGGSTRDRTIRITKEIT
ARTKIPTVAHLTCVGSTRDQILEILTHYRDAGIKSIMALRGDPTGGPSTPWVSTPGGLNH
ADELVALAAEFGDFTIGVAAFPDGHPASHGDFDLDVNVLVRKEELGASFATTQFFFDASR
WSALVDRLRERGSNLPIIPGILPVGNVKQLVRMSELTGTPIPAKVLQRFQAVESDANAVR
ALGIEIATQLGQDLLAAGAPGLHFYTMNSSSATQEIYANLGIAR
>A0A2N6NLD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beauveria bassiana|TrEMBL
MERITDKIAALPADGEYFSLEFFPPKTAMGFSNLRDRLHRMEQGLRPLFVNVTWGAGGST
ADKSLELAELCQRELGMTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRTDE
YRTTDDDESDNDGAADGQAFVWAIDLVKYIRKKHGDYFCVGVAAYPEGHADESHPLGQSL
AHDLPYLVEKVQAGADFIMTQLFFDIEAYDTFETTLRGHPSGAFQTIPILPGLMPIQSYA
MIKRTAKLSHAAMPPALLDRLNAVKGDDERVKAVGVDILSELVEQVRTVKTKTTPGRPRG
FHFYTLNLEKAVTFILERTHLIPDAPDEEEVVIVDAGPTSAPFLQVNGHAIPPPQRSHSR
SSRRHSSVGSDPHNRVIVGSGSGRRTNPEWEATGAEAAVPAAVSQLNARANTLAISEGEG
ALGREATWDDFPNGRFGDSRSPAYGEIDGYGVSLHMSVAQAVRLWGHPASSRDIDDMFVR
HVRGELSALPWSEEELLAESSTITTHLAALNRRGWWTVASQPAVNSVRSTDPTFGWGPAN
GFVFQKAFVEFFLSSADWASLKDRLQAPGVREVVCFYAGNAKGDLVSSDNSGSAAAATAA
ASTNAVTWGVFPSKEIVTPTIIEEVSFRAWCEEAFGIWDEWSRVYAKGSPSATLLSGIRD
DYWLVNVIHHDFVDQQALWDLLLA
>A0A0B7GNE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFNIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A0K8M8N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. actinidiae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKNAGIKRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A7V8PXE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium carotovorum|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLRDIAQDYWESGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTTMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A2H3HEI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella zeae|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDAEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSVEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFNGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLERLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAVYPEWEATGLEAGGRAEAVNTRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWDYPKTRQDINDLFVKHIQGELSAIPWSE
EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PANEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGSTEASPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNLIHHDY
VNRDALWEVLSS
>A0A5W7Z4C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella derby|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>V5VBJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A061HGD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blumeria graminis f. sp. tritici 96224|TrEMBL
MEKISNKIKALPPGQNYFSLEFFPPKTSTGTANLRARLERMSRALCPLFVTVTWGAGGAT
ASKSLDLAAMCQRDLGLTTCLHLTCTNVTQEFVDGILERACALGIRNILALRGDPPRQEF
IKNHSDKKDTVEFEWAIDLVSYIKAKYGDYFCIGVAAYPEGHADRENPDEQNLMHDLPYL
VDKVNAGADFIMTQLFFDVKAYDHFEKVLREHDSGCFKELPIIPGIMPIQSYQTIKRTIK
LAHARIPPEFMARLDSVRSDDALVKQRGVDIVSEIVTHIKHTPSSAPGTRGFHFYTLNLE
KAVALILQRTSLIPSSQAIDELESNRNANSNECEPNTNCTCSQDTRQATNSVDPDLFNRV
VITEAKPSDPQIEATMSEASALSKPDYSRAATLAIIEGEGSLGRDATRDDFVNGRWGDSQ
SPAYGMIDGSCVILHMSRKQAIQLWGYPSSIEEITSIFLQHIEGSISAIPWSEDDLCHES
EAIKVPLRALNRKGWWTVASQPPVNGISSQHPVFGWGPPRGFVFQKAFIEFFLPSAAWSA
LRTRLESSLIAPDVSWYACNAHNVFKSSNPTINISSEMGRTSRCTNAVAWGVFPGREIIT
PTIIEEVSLRAWAEEAFSVWSEWARICAESGSKSGKMSREFLEGVYEDLWLVNIIHHDYF
KENALWEILLE
>A0A083ZBV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MVTKRIMLKLPDISAASLIPASIEASPAQVLGPASLAGIFPRGVRVYLTDTGAASQEKLV
DAATHLRNLGYEPVPHLAARRIPSRVEFEEQVKRLAGEADVTDVLVVGGGVDRPAGPFAS
SMDMLSSGIFDRYGIKKIAIAGHPEGSPDFSEETAIAALRLKRDFGERSDAAMRIVTQFG
FDPARFIAWAEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LARGHSPDSIVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVSRGSWQTRDAGRPAP
ADSMAG
>A0A3M7HUQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMSYDAEIFIEWAKKVRAAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAQLFVKYMSGKVETLPWSEQPISPESNVL
TNDLVNLNSRGLLTINSQPAVDGMKSSHPVYGWGPNNGYVYQKAYLEVLIPPSLIAELIR
RMDANPDITYYAVNNSGELKTNAPQDGGPNAVTWGVFPGKEIVQPTIVETISFLAWRDEF
YHLGSEWAKCYDEGSRSKNLIKEITESWYLVNIVDNDFRNMRGIFPLFDGLKVDGVEPTA
AAVNGVALSLVNGEAVKGDVEKKEGARKPEVNGVPDGNNAVNHADGPAVNGEVKK
>A0A0D7LPI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A081QLM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLSKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A083ZT86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNAEMDAQLWETVAELKKWDPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYQ
PHPEGYENAAALVKGLREIGDFEISVSAYPEKHPESASETVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPRFLDERFEGYD
EDLEGRARVAAEVAAEQIADLQRRGFNEFHLYTMNRAPLVDAVLENLGLQRLRRSAA
>A0A1P8KHK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHNVAGIVITPHMLRALAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVKT
KNELVPELAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDLCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A069B5T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A066UQ51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio fortis|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSNEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELIQIADDYWANGIQSIVALRGD
IPPGGGAPEMYASDLVKLLKARHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>Q93ER8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus luminescens|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTTEMEKTLWKSINRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGD
LPENGEKPKMYGSDLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQLKRFAVMTNVRIPSWMTRMFD
GLDDDPESANLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A5C4MD92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mumia zhuanghuii|TrEMBL
MSTARRLSEDIAAPAASFSFEFFPPKSDAGERALWTAIRELEPLHPTFVSVTYGAGGTTR
DRTVRITERIATETTLRPVGHLTCVGQSRDDLRTVLGQYAAAGVRNILALRGDPVGGPGA
PWTSHPDGLDHGVELVSLVSGLGSFCVGAAAYPKGHREAPDLDADADVVVAKARAGAEFA
VTDFFFLAEDYLGLVDRVRARGCDIPIVPGIMPITNLAQISRMAELSGHSVPASVVSRLE
PWVDDPEGLRDEGTQIATELCSSLLERGAPGLHFYTLNRSRATRQIYQNLAPLVVG
>A0A3V7ISD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella rubislaw|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2X1ML88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPCTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7W2Q954|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas juntendi|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVQVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRTETGDHFHLEVAAYPEMHPQARNFEADLGNFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLALWNNLKLPR
>C3SIS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MNFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A509LF88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSELKSGSNLEKVLTAGHFAFTGECGPPKGANVAHLKEKLSHLKGNVDAVNMTDNQTAVV
RMSSMAGSALMIGEGLEPNFQMVCRDRNRLAIMSDILGAYALGIRNMLCLSGDHQTFGNH
PEAKNVHDIDSMQLIALVKKMRDEGKFLNGDDIDVPPKMFIGAACNPFADPYEYRVYRLA
NKIEAGADFIQTQCIFNMDKFRDFMKKTVDMGLHEKCYILAGVTPMKNAGMANFMSKFVP
GMDIPDSLIKRLKGVDKRDQSEEGIKFALEQVEEFKEMEGVAGVHMMAIEWEHMVPEIAE
RAGVLPRPVV
>A0A8C3PLV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calidris pygmaea|TrEMBL
MVNETQHTCSPSSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQESGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPAQQ
>A0A347CYW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia solanacearum|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILNTYRENGIRRIVALRGDLPSGMGEIGEFRFANELVEF
IRHETNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLLRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>A0A2K7SSE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio rotiferianus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDATRDELIDIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A6S7I2B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paramuricea clavata|TrEMBL
MMVQDTFESGVLTKRKCPSPSSGTSTPLSLIEKIKQSIALEKNFFSLEFFPPRTPAGAAN
LIGKLEKFSSGSPLFCDITWHAAGDPGGDNETSSMHIAGAALNYCGVEIMLHITCANETK
ETITRHLYKAKSMGIRNILALRGDPPHGEDFEVVDEGLVYGTDLVKHIRQEFGESFTICV
AGYPQGHPDCSSYEEDLLHLKEKVDAGADFIITQLFFEVKTFLKFVEDCREIGIDVPIIP
GVMPIQSYDSLRHLVKLSKLSIPQEILDAIQPIKDDDLAIRNYGVDYTVKMVNELLSSGV
PGVHFYTLNREVATTDVLKQTNLWSLEPLYARSLPWKPSANVKRIKEEVRPIFWASRAKS
YVHRTSEWDEFPNSRWGDSAAASFGDLSDYHLFYLRNRTKKATLLKMWGEELTSVQDVYD
VFVCYISAEKNANGTKVTMLPWNEDELAPETSQVSEDLVELNRTGVLTINSQPHVNAAKS
TDPVFGWGGAGGYVYQKAYLEFFTRKELVDKLLKVLETDFPSVSYHVVDHKGEVDIISED
LASPVAVTWGVFPGKEIIQPTVVDPVSFQIWKEEAFALWQQQWARLYPEGSKSREIIDTI
HDNYLLVNLVDNDYVAGNCLFEAIKKAVELVDTKEQTDPSVVTEDDGINSG
>A0A6B1H2K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MTRIADLLGAQNTLSFEFFPPADEVAAKQLEKTLDELAGLSPSFVSVTCGVGGDGHDRTR
DIVTDICRDRTFPAMAHLTCVSHTREGVAALLDDYAAAGVANILALAGDPPDGSAISGDF
HYASELVEVIRDHPADFSVGVAAHPEVHPRSTNRASDRQHLAAKLSRADFAITQFFFDPA
DYVQLCEELADLGCQQPVIPGVMPVIWPKSIRRFADMNGSTVPEDLFTRLESMPAPDRIG
AAAESAAKLSQTLLDAGAPGIHLYTLNRPEASTQITELLNL
>A0A815J4V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sordida|TrEMBL
MTLTHTEKNTASNHCHIHENGIGAPKICHSLDNFSELKRSESEHTCLTVKGCSLHPVKYI
SLKEKLQNRISNNDRWYSLEFFPPRTTNGAVNLIGCLERMAVGEPLFCDITWHTAGDPAG
TKETSTMMIANTMLNYCNIDTMLHITCYGAKKATMIEYLSKAKDFGIRNLLALRGDPPVG
EKWNPEKTDFRYASDLVKFVREHFGDYFVICVAGYPKGHPDSKSYEEDLGYLKEKVDCGA
DFIITQLFFQAETFLKFVSDCRAVGITCPIIPGIFPIQAYASFKNIVCLTKLDVPDEITA
YMESIKDNDEAIRNFGVQTCVDLCKALLNSDKVHGLHFYTLNREYATTEILKQLGFGFDD
PPLRALPWKKTSKNYVRSKEDVRPIFWSTRPKSYIHRTSNWNEFPNGRWGISSAPSFGVL
TDYHLFYMKIDATRDELLDEWGHELTCEQDVWKMFACYIRGEKNGSDKIVRHFPWKDEEI
SLETHLIHNELIEYNRKGILTINSQPAVNGKPSTDSIFGWGERNGYIYQKAYLEFFTSAN
NIPALRAVLKNFPGVNYHFVNKSGDVNETNTDHEQPIALTWGVFAGREIIQPTVVDTVSF
MIWKDEAFSLWMERWGKLYEPGSSSYSIIEQISNTYFLVNLVDNDYPQGSCLWAVLDAMF
EYQQKTNQDINHS
>A0A5N5TZC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella algae|TrEMBL
MAFHHAQHAHSLNQSLSELNGDINVSFEFFPPSTPEMETLLWNSIQRLEPLNPKFVSVTY
GANSGVRDRTHSVIERIQQETELVAAPHLTLVDASDEELLELARHYWNSGIRNIVALRGD
LPEGSPKPTRFASDLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIEAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVGNFNQLKRFAAMTNVSLPGWLHRQFE
GLDNDPGTRALVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A5Q2KBP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cancerogenus|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLRRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A165JGN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella baltica|TrEMBL
MAFHHAQHSQSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPGWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A6N8HWB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caproicibacter fermentans|TrEMBL
MKIVDILNRQGVSVSFEVFPPKKDSDFSQARQVVTEIASLSPSFLSVTFGAGGGTSKSTA
QIAELIQRCGVPALAHLTCVSSTRDEVSGVLEDLKSRGIQNVLALRGDIPPGMEFPSPRQ
YRYAKELVRQIKSSGDFCIGAACYPEGHVECEHKEDDIDHLKEKVDCGCDFLTTQMFFDN
NIFYNFLYRVLAKGIRVPVAAGIMPVTSSKQIRRICALSGTALPPRFLAIVDKFSDNSKA
MKQAGIAYATEQIIDLVANGVKAIHVYAMNKPDVARKIMENISDILSDGQKGLD
>C6PVX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium carboxidivorans P7|TrEMBL
MSLLKEAFERGEFGITAEMAPPKGIDLSHLIECAKAIKGRAHGVNVTDFQSATLKATSLA
TCKVLKDAGLEPVLQITGRDRNRIAIQGELLSAGVFGIENVLALTGDYTMTGDHPGAKPV
YDLDSVGILSVASTIAQGKDMSGNDLTGTPKFYLGACVTPRYDPLELQILKMEKKIKAGA
KFFQTQAVYDIDTLKLFREKTKHLDAKLMVGIIPLKSAGMAKYMNKNVPGIFVPDELIER
MKGAENKVQEGIKISGEFIKKVKEEGLCDGVHIMAIGAEENVPLILDQAGL
>F9GPB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus haemolyticus M19501|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIESYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPE
>A0A813PW86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adineta ricciae|TrEMBL
MTLGNSENQTVPNSHNMHHHETHHETRHLTQVLKRAESEGTNVAAKGCCLQSTRYVSLTE
KIEKRIENNDRWYSLEFFPPRTPSGAANLIGCFDRMAAGQPLFCDITWHPAGDPASDKET
SSMMIANTMLNYCGIDTMLHITCYGAKKEAMLSYLNKAKDFGIRNLLALRGDPPVGEEWD
PNKSDFRYGLDLVKFIRQHFGDYFVICVAGYPQGHPDSVSYEEDLGYLKEKVDHGADFVI
TQLFFQAETFIKFESDCRAIGITCPIIPGIFPIQGYASLRNIVRLAKLDVPKEILACIEP
IKDNDEAIRHFGVQTCLDLCRDLLESGKVHGLHFYTLNREFATIEVLKKLGLWLEEQPMR
ALPWKKTSSNFSRSKENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGMLTDYH
LFYMKLDASRDELLDEWGRELTCEEDVWRMFACYISGEKNQIGKVIRHFPWTDEELSSET
SLIQTNLVEINRRGVLTINSQPAVNGKPSSDPIVGWGTLDGYVYQKAYLEFFTSADNIPA
LRHVLKSFPNVNYHFVNKSGKVNETNIDDEQPIAVTWGVFTGREIIQPTVVDSVSFMIWK
DEAFSLWTERWGKLYEPESRSHAIIENIADTYFLVNLVDNAYPEGSSLWTILEAMFEYQK
NAKNTNNAS
>A0A384CEU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ursus maritimus|TrEMBL
MDHPTPKVLPARPRGPSLGMWALEAGRVRFSVPPSISRNRAMVNEPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERHDRLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQITG
YLQKARRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFQFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQQLLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFAHYLS
GEPNQQGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLENCLWQVVEDTFELLNQPAPEGETEAL
>A0A7R9N550|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon GB37|TrEMBL
MRVKDILNATKISFSFEFFPPKTDTGWKQLFDTISELMLLKPSYVNVTYGAGGSTRDRTY
NLVTQIQRETGLTVVSHLSCIGSTKEEIRSILEKYNQSGVENILALRGDPPKGEKLSSLK
GDFKYAADLVAFIKKHFPHMSIGVGGYPEGHPETPNRLKEIEYLKAKVDAGADYIVTQLF
FDNRDFYDFCERCELVGIHVPIIAGILPITSYQGMIRMAELAAGSRLPAPLLKSVMRAES
DEYVEKIGIHWATEQVRDLVDHNVRGIHFYTLNNSRPIFKIYEYLGVRDSIQLSSQPGHI
IRRDTKVE
>A0A6J6BSZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSAIVEALNRRTNGGKPTLSFEFFPPKDDAGFDTLNESFEQLQRLSPDFVSVTYGAGGSN
RERSIAVVESFSSRVATIGHLTCVGATKQSTLAVIRQFEQAGVAGILAIRGDNPADNPDA
LSQGELKRAVDLVSLAQESSSLPVGVAAFPEKHPESVDIAADVRVLKIKQDAGAKFAVTQ
LFFAASHYVELVDAAREAGVTMPILPGLMPIANAKNVLRMAQLSGASVPSDLHDRLISAT
DEDAAREIGMAYTVQLGRELLAAGAPGLHIFALNQSKAATRVAKEVGLA
>A0A6J7U9W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARITELLARGRTFSFEFFPPKTDAAQLSLGRTIAELETLHPSFVSVTYGAGGSTRERTR
DLVTWMRRETTISPMAHLTCVGHTRSDIEEILQAYVDAGVENILALGGDPPTDPADVRPS
DYQFASDLVAELQAAGQFSIGVAAHPEVHPRSSSRTEDREFLAQKLRRADFAITQFFFEV
EHYVRLVEELAALGIDKPIIPGIMPVTNKSQVQRMAEMSGAAFPQDLSERLAKVEDPEEV
RRIGVDAATELCAQLLDAGAPGLHFYTLNRSSATREIYANLGLPVVSSAS
>A0A6J6VTM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARIADLLAAGRTYSFEFFPPKTDGAQLSLGRAIGELEPLAPSFVSVTYGAGGSTRQRTH
AVVSWMRKETTLTPMAHLTCQGHVRAEIREILNDYAVDGVENILALGGDVPTDGESAPSD
YTFASELLEDVVADGRFSVGVAAHPELHPRSPDRATDRKFLAAKLSRADFAITQFFFDLD
VYVQMVNELADLGVTKPILPGIMPVTNKNQIRRMAELSGAAFPTWLSERLDRTDDAEEIR
RIGVDAATELCQGLLDVGAPGLHFYTMNRSTATSEIYANLGLSPTR
>A0A634EXC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enteritidis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPPWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6P2QP09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNTAAATRTICERLVM
>A0A3T3IQH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella dublin|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A553R3T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Danionella translucida|TrEMBL
MTDPSPNQLILPGKWAGPVRQRLLCHACAHSAHAARELGRSAYREPPNDQEQLVGSMVNQ
RADVGWQSKSDSSGASNSGESSIESSRCSTPVLDTDRTDRLCDKMKRRIESGDHWFSLEF
FPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVKYCGLES
VLHLTCCNQTKEKITEHLSKAKHLGLKNIMALRGDPVGEDWVEEDGGFSYATDLVKHIRQ
EFEDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGSHFIVTQLFFRAETFLRFVRDCR
AIGISCPILPGVFPIQGYHSLRQLVKLSKLEVPEEIKQVIEPIKDNDAAIRNYGIQQAVQ
MCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAISAHPKRKVEDVRP
IFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEE
LTSEQSVYEVFTTYISGQSNCSGHKVLCLPWNDDPLASETNLLKDQLEKVNRRGVLTINS
QPNINGKPSSDAVVGWGPAGGYVFQKAYLEFFTSSENVTALLEVLKRYEPRVNYHIVNVQ
GRNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFMFWKKATKEKNNLLLIPYASRSSL
ASSSRRSQSRRGTPQSPGFLPGIIGRIRCGLSIRGLALTEELRNRLKESTETDVETRYCL
ATRSPPVNPTRVSLAVFVSLVGDLTLDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFL
VNLVDNDFPLDSCLWKVIDDMFELLDSSHGARQQESEL
>A0A440IP17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAKIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A347VVB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter saguini|TrEMBL
MQNSDIIEDFIAKIHSPKCLTYELCPEKSGSVENLIKKVQKAGLETNNLTKEFIESRLSL
VDNISNSLDSKIESSKNHNFIESNSNTDSTNTSCMQKNLQDSKNLQKDSKNIKNQTNKDT
INIDAFVCTDSPLAILKQNSGLASIKLQKKIKKPLICTISMRDRNSLALCGEIMGLNDFD
IRLFLALSGDPLKLGDQPQAKAVFEGNSLEILRIISLLNQGKDSAENELKEPLKQIYAFS
VINSYAKNMQILKNKMESKIKAGAIALFTQPIFDINVASELIESCEIFNKKHGKNCALML
GFFPVLRYKSAKFLHDKLPGVYIPDIWLENLQNALSESKENEREIGLKMSGELFKKLYET
YPKIHFMNNNNTMIALRILKNVL
>A0A183DLR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gongylonema pulchrum|TrEMBL
MFVDVTWHFGSDPGNINKETSSSSIAAGCLDYCGVDTMLHITCAQYTKEQSIRHLEQSKA
LGLKNILALRGDLPQQVAIFMRFCRAALERCIRQQKRILQRPCLCVYVCLCVCVCSSVRV
FQLVNHASFEAEILPVCSPVRYHPRNAVSTLTHVWAPRTDM
>A0A396ESB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides uniformis|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPKELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>K1J5I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas dhakensis|TrEMBL
MGFHSARQVEALNQSLADLSGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPEMYATDLVALLKAEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDDDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQP
>F9D0T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella dentalis (strain ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043 / ES 2772)|TrEMBL
MKVIDLINDDKHGQSFSIEVLPPLKGNGTEALFRNLDKMKELNPIYINITTHHSEYVYRE
LANGQFERLRIRRRPGTIAIAAAIQQRYDIPVIPHVICSGATREDIEYELIDLQFLGISN
LLLLRGDKAKEDRMFTPTPNGHAHTTELMEQVNRFNAGFFDDGTPIRHPGATFHYGVAAY
PEKHEEAPNMEMDMAYLKQKQDMGADYAVTQLFYDNRKFFEFVERARQMGITIPIIPGIK
PFAKLDQINQVPKTFHCDMPQELAAEAVKCRTDADAKALGIEWTTEQCRGLFAAGVRHIH
FYTVSAVDSVVAIAQQLMPCSSAK
>A0A2E8S372|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MTSRLLEALDERVLVIDGAMGTKLMDQGVSVGSGLDYANLDAPGVVQAIHRDYLAAGADI
LETNTFGANRFRLAKHGLTDKVRRINRQGVMLARSVAGNERFVGGAMGPLGKPLAPIGTV
STDEAREAFHEQASALIEAGVDLILLETFSDLSEIKIALEAVRSIDAELPVAGFLSFTDE
CKTIYGYKPEECARSLMEGGAQLVGANCSSGPEHLHEVIDRMHRVQDARVLVLPNAGLPA
YVDGRYVYLTGPEYFARHAQQFIEQGVRAVGGCCGTNEHHIRSVRAIVGTRAPVAVEDRT
KAREISVVESEEPARTDTKQAASGGRFIKKIEEGTFVVSVEIDPPKSVDASKMIRGAAML
KQAGVDAINIADSPLARARMSPLALATLIRQEVPIEIILHMSCRDRNVLGLQAELMGAQA
LGVMNILAVTGDPPSVGDYPDATGVFEVDAIGLIGIMERLNQGVDLSGKPLKFNTEFVIG
CASNPTSDDVDREIERFLRKEEAGVHFTMTQPLYELESLERFLEKTSCGVPVMVGILPLR
NGRHAEFLHNEVPGMFIPEDIRARMKAAGDQGPQEGVQIAREFLEQAKPLVQGTYLMPPF
NRFEMAVEVIKGLVED
>A0A6H0CX89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DSM 40868|TrEMBL
MNPALLDDFSLEMTGKDVPRLEEAQGGIPPGTRINITFLAGEDTATRLTAARAVKRLGFV
PVPHISARRLPSRPALEEFLTGLAADGTAENVFVVGGDPARPEGPYEDALAVLRTGLLRH
HGVRHVGIAGYPEGHPGITDRALWTALTDKAAALDADRFDGDVITQFGFDADPVLAWLED
LRARGVRLPVRVGVPGPAGVRRLLGYATRFGVGTSASVARKYGFSLTNLMGTTGPDRFLH
ALAERYDPGRHGVVKVHFYTFGGLRATAEWIDGFRRQHAPAPASSNR
>A0A4R6DT67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scandinavium goeteborgense|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCASTGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A164GIN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. EPR-157|TrEMBL
MVDRLRTDASTPIPFSVEFSPPRDEAAEGRLWRAVREFEQMRPAFVSMTYGAGGSTRDRT
VRVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGAYADRGISNILVLRGDPPGDPLGHWE
KHPEGVEYAEELVSLVRELGDFHVGVASFPEGHYRAVDLDQDTRVLVNKLRAGAEYSITQ
MFFDVDDYLRLRDRVVACDPEQGAKPIIPEIMPITSLRTVRRALALSGSALPKSLDDRFT
AAAGTGPEEDRAAVREVGIALATEMGERLIAEGAPALHFITLNFARATREVLTNLGLCAA
RV
>A0A0Q4G2R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf20|TrEMBL
MTNISVPQLAEARRALEEPLFADLAGDVGISFEFFPPKTEKMDAQLWDAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPESHPESGDPNADIDNL
KRKLDAGASRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKSAETVAAA
>A0A1T5KFY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Krasilnikoviella flava|TrEMBL
MVAEASLPPTPALPARPTISFELMPPRRPDAAPKFWETARRLVAARPDFVSVTYGAGGSD
RATARQVVSTLLKGTPVLPVAHLTCVGAHREDVSAVIDDFLDAGTRAFLALRGDPPKDQP
DWRPPADGVASSIELVQLLREVEARRCASDPGAALRGAARPMTIAVATFVDGNVQAGTTR
TQEVRRLKEKQEAGAGFAITQLFYEADSYTDFVAEARAAGVTIPILAGQLPTTEPRRLRR
VEELTGVRAPRHLLDALDAAGDPEAQHAYGTARAVELAQRVLDAGAPGIHVYTFNKYRPA
LDLLEGVHLGGPAPADDPSDGADLARRPWVPSIPTQAPAV
>A0A1B6VK30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter cerinus|TrEMBL
MTISVGQVRADLMTESSIELLPSRILELSGVLPDLACGSRVFVTWLPGVPFADVLAACDL
LKLCGYLPVPHVAARSIRDEGHLQEICSALTERDIPRMLLIAGGADKPAGIFADTVQILE
TEIPVRTGIRTVYVAGHPEGHPQATEATLLEYMRRKQELARTQGLNMQIVTQFCFDSAPV
LAWEKRLRDGGITLPINLGIYGLTTPKTLVRYGLACGVGQSLRFMQRQRWKLHRWFMPCN
PQHLVDAVAQEIAQTPDTNFRGLHFYPFGAIARTLEWRRALSLSTGDHS
>J3K515|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccidioides immitis (strain RS)|TrEMBL
MHVKEKLAHSEASGRPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPPREKES
WAPTEGGFRYAKDLVKYIREKYGNHFDIGVAGYPEGCEDEEDPETLMKHLKEKVDAGGTF
IITQMFYDVDIFLDWVKRCRENGIQVPILPGIMPISTYASFLRRSNWVKCKVPESWMEAL
EPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQATKMVLEELKLIPSYETP
LQKPLPWRQSLGLGRRDEDVRPIFWRHRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSIKDLSAIFIRFLEGGLDRLPWSESPITEETDDIKHDLID
LNNRGFLTINSQPAVNGMSSSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNP
DLTYYAINKNGELKTNTSDSPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRLGDDWA
KCHDARSPSRQLIQRVMDEWYLVNIVNNDFHKTHDIFNLFNDIVVKDLDVEATGIEESTS
QPANTNPERQNGDAAQTKDILVGTNGTSN
>A0A0S8I7K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium SM23_61|TrEMBL
MSKLAQALESRKFVVTGEIGPPKGVDLGKCLTDADHLRNKVTAINVTDLQSAVMRVGSMA
VCAKLIEKGLEPIYQLTCRDRNRLALQSDLLSAWVLGIQNVLCLSGDHPSLGDHIDAKAV
FDLDSVQLLKAVALLKDGKDMADHELEGKPDFFSGAVVNPGTDALEPQLIKMEKKIEAGA
KFFQTQAIYEPEKFEHFMNRVQKYGVPVMAGIVVLKSAGMARFMNANVAGITVPESMIEE
MAKTKVENRKEKAVEIAARIIRQIKPFCQGVHIMPLGWDELVPKIIEEADLD
>A0A2M6GG76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagales bacterium CG18_big_fil_WC_8_21_14_2_50_42_9|TrEMBL
MKVTEHIKNASSTLFSFEILPPVKGTSIQSIYDGIDPLMEFKPPFINVTYHREEYVFKER
GNGLLEKISIRKRPGTVGICSAVMNKYKVDTVPHIICGGFTKEETENALIDLNFLGIDNV
LVLRGDTIKTESQFRPHPDGHAYACDLLEHVVNLNHGKYLDEDIANPLPTNFCPGVAGYP
EKHTEAPNLVADLKYLKRKVDMGAEYIITQMFFDNQKYFDFVRACRDMGINVPIIPGLKP
LTTKNQLKLLPNLFHIDFPENLVNAIEQASSPQAIRQIGIEWAIQQSKELIKFGVPCLHF
YTMSKSDAVVSIAKEVF
>A0A498DY61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Z26|TrEMBL
MALGTPVTRTDRTPTVRELLASGEQSFSFEFFAPKTAKGERSLWNALRRIEAVSPTFVSV
TYGAGGSSREGTVRNTERIANETTLTPVAHLTAVNHSRAELRNVIGQYAAAGIRNVLAIR
GDPPGDPMGEWVRHPEGVTYASELVQLVKEAGDFCVGVAAFPEMHPRSTDRDTDVRHFVD
KCRAGADYAITQMFFHAEDYLRLRDSAAALGCATPIIPEIMPVTSVAQIERLAELSNARF
PDGLVERIHAAKDDPAAVRSIGIEYATELCAGLLAEDIPGLHFITLNHSTATLEIYENLG
LHRRSPGRTAQT
>U2IZ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. F0091|TrEMBL
MDNNITDIKQLLNDETDEKHFSFEVLPPLKGNGTASLFRNIDQLKEFNPTFINITTHHSE
FVYHEREDGLLERQSIRRRPGTIAIAAAIQQTYGIPVIPHVICSGATKEDIEYELLDLQF
LGIENLMLLRGDKAREDRMFKPVKGGHRHTTELIKQVNHFNEGVFTDGSIMKHPGKPFVY
GVACYPEKHEEAPNLEQDLRYLKQKQDLGATFAVTQLFYDNEKFYNFVDQARKMGITIPI
IPGIKPFAKLSQLNVIPKTFHCDIPKKLAELALICKSDEEACLLGIEWTVRQVKDLYAHG
FNNVHFYTVSAVSSVCEVMRRLAETGLLQKNSK
>A0A291FYP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter piscinae|TrEMBL
MTTPDISFEFFPPQSLEASFRLWDTVQTLAPLAPRFVSVTYGAGGTTRDLTREAVATLHN
ASGLNVAAHLTCVNATKAETMTIADQFAEAGVREIVALRGDPPKGAAGFEPHPDGYANSV
ELIAALAERDQFSIRVGAYPDRHPEATSARADVDWLKRKLDAGADEALTQFFFEADTFLR
FRDECAKAGIDTSRITPGILPIENWKGARNFAKRCGATIPAWIDDAFDKAIRDGREDLLA
TALCTELCSDLMDNGVDKLHFYTLNRPELTRDVCFALGITPDVSLENVA
>A0A396NWR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM28-20LB|TrEMBL
MKIRDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPELCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A5E4PIU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquicella siphonis|TrEMBL
MKNQSPLVISFEFYPPKSREGAVNLQQSALALDAMTPDFFSVTFGAGGSTREGTIDIVKT
LQEKTRTAVAPHISCIGFNREGLVSVLRQYKSLGVKRIVALRGDLPSGMGSIGEFKYASE
LVKLIREETGDYFHIEVAAYPEYHPQAKHALSDVLNLKRKIEAGANGAITQYFFNPDAYF
YFLEECAREQIFIPIVPGIMPIMHFSKLMRFSETCGAEIPRWLYKRLEAYGDDVESIRQY
GIEVVHHLCQRLIVGGAPGLHFYTLNHAELSLQILQQLDINSMRMNEKVYEAIKN
>A0A2M7M803|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piscirickettsiaceae bacterium CG_4_10_14_3_um_filter_44_349|TrEMBL
MHSQQKYLQNLSLEFFPPRTDVGMEKLKTVIESLKVIQPHYMSVTYGAGGTTQARTIETV
DYIQTQTEFDAAPHLTCIGATAESVCALLDTYSKMGIQRIVALRGDLPSGMMDPGEFKYA
SDLIAFIRQERGDQFHLEVAAYPETHPQARNCDIG
>Q2C722|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium sp. SKA34|TrEMBL
MSDQYQPTPESELRVRYNDITRGVYFIGTTPPKTSTAIEDVEDIADRLVERIRDLAIDGL
IVYDIQDEASRTNKPRPFPFKSTHDPRHYSSLLNKKTDRPVITYKSVVQSETEAFDEWLN
EAWDEYRVRDMVLVGSPSAKNDVSLPLSTAYQTLAENRNDFFTGGIMIAERHAKKGNEHE
RLIEKYKQGCNFFISQAIYDTQATIDILTRYAIECKELGLKPQRIILTFSPCGSAKTLEF
IEWLGVSVPEATSLRILNAENPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRKE
EIDGSILLYKLLRSSMDSHLAKHEFRVLKRRARANKLASM
>A0A807YG76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia anophelis R26|TrEMBL
MKVTEHIAQSKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGEKYFEPTKGGNRYASELVTQINDLGKGKFLHGEISGNDTNNSFCIGVAG
YPEKHLEAPSMQYDLKMLKQKVELGADYVVTQMFLDNQKYFEFVKLAREAGIDVPIIPGI
KPFAVKKHLQLLPQVFKIDIPEDLVNAVSQCKNNEAVKQVGIEWCVQQCKELLDFGVPAL
HFYTMGKSDNIQKIVSEFF
>A0A378Y084|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus polymyxa|TrEMBL
MKPDLRTVLNREIIVGDGAMGTFLYQLGFPVNTSYEELNITSPDVISDVHGQYLNAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIAKAAAGPEHYVVGAVGSICGGKRLNISK
LELSRNYEQQIDALLSEGVDGILCETFYSLDEMRIALHSVRNYSDIPVICQFAVDQVGRT
QDGFLVSEAFSTLRSEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAASFVDLGTRLIGGCCGTTPDHIAAVSKALKNLQPPPLAPKEALS
TESIHVVEQTANEGGRGNGRHASEPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHALK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLVKKIASGADYIMTQPVYDPELIIAIAEETRHLEIPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGSEGRAMGVSIAKELLDTAMEHFNGIYFMTP
FMFYEMTAELTSYVWEKSGRAQAPLFRL
>A0A2T3X1I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. Nf4|TrEMBL
MSARLSARAHAFINAFSLEVSAKALPALREQAARIAPGTRVSIPYLASEDDEARLAAARA
VRELGFAPMPHVSARRVPSRAALEHFIGRAVSEAGAECCLLIAGDLSTPAGPFADSASII
GTGILERAGIKAVGIGGHPEGHPVMDDAQRWQVLAHKCQAIEARGMAPMIVTQFAFDADR
VLAWLHALRGHGISHPVLLGVPGPASIARLVRYATMCGVGASTSMLARYGISMGRLLGTA
GPEAFVDRLMQGLRDDDGPVSPHLFPFGGIAPSLDWIDAYRQRGTPGAR
>A0A5C8PHL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vineibacter terrae|TrEMBL
MSPDTGPLSAAMPTREFPARKPSKLVVSFEFSPPRTEAMAQTLWQSIERLAPLQPAFMSV
TYGAGGSTRQRTHETVVRIRRETGIEPAAHLTCVAATRGEIDDIARAYWDAGIRHIVALR
GDPPRESGGQYVAHPEGYPNAAALVAGLKRIGDFQISVAGYPERHPDSPDDKADLDNLRR
KVDAGADRCITQFFFDVDDFLRFRDRATAMGVQVPIVPGIMPVSNFAGIARMAGMCGAKV
PPWLAALFDGLDDDAETRRMIAATVAGDLCRKLESEGVSAFHFYTLNRADLTYALCHLLG
VRPAARRAE
>A0A143YIB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus palustris|TrEMBL
MKIESKFQKKKPVLSFEIYPPKRDKAIQNIDETLAILSELDPDFISVTFGAGGSHTNNQT
VALAKRIKQQYGIDPLVHLTCLNYSKFEMCEMLEELKDADIDSILALRGDTNPAVEAKKD
FRYASDLVKFIKQYGDFSISGACYPECHTESKNKVQDISYLKGKVDSGVQHLISQLFFDN
NVFYTFQEHIQIAGMHVPVEAGIMPVINKAQIDKMVTLCGASLPEKFSRIMQKYENNKEA
LFDAGMAYAINQIVDLLAHDVDGIHIYTMNNPIVAKRICDGIKNLI
>A0A0Q4KTB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf33|TrEMBL
MEEARRALDAPLFADVAGDAAVSFEFFPPKTEKMEATLWESIETLSPLGPRFVSVTYGAG
GTTRERTHATVARIARETNIPAAAHLTCVEATREEIDAVANEYWDAGVRHIVALRGDSPT
AGTAFQSPEGGYANAAALVEGLRRLHPFEISVAAYPECHPDSADATADLDNLKRKLDAGA
TRAITQFFFEPETFFRFRDAAAAAGISAEIVPGIMPVMSFAAVQKMSAMCGTDVPPWMAR
LFEGLDDHPAARQLVAATVAAELCRKLYAGGERAFHFYTLNRAELSYAICHLLGLRPQAG
ARAEAA
>B0CU22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686)|TrEMBL
MKITQKIQQSANNDKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGMETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPSGKDE
WEAVEGGFVHGIDLVRHIRRDYGDYFDIAVAGFPQHMALPPDERDQEIQWLKEKVDAGVA
FIFTQMFYDVQLFIDWVKAIRAAGITIPIVPGIAPIQTWNGFQRATSLAKIVVPQSFLDA
LEPIKNDDEKVREVGTRLVADMCRRILKEDIGIRGLHFYTMNLEKGTKMLLEELNLVPRI
ETIKPLPWRQSLTPNRRQESIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTVKDALKLWGHPTSFADIASLFSRFCTKKLSALPWSDQAPSQETSVIAEQLA
TMNEFGFLTINSQPAVNSARSDDPVFGWGPSNGYVYQKAYLEFFVNPTLLNLLLTHIERD
SNITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGQQ
WAKLYEANSPSQKLITELMDTCFLVNVVHNDFHEPDAIFKPFLKAGAEYVAAKAKATAVN
GH
>A0A0X8JE67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces radicidentis|TrEMBL
MIHPSTPEGTAPGAPSPDRPSLSLELFPPRPGPHASQTWGALDRLLATGPDFASVTYRPT
FITTVGGAPRAEAPTRPADADERARAVTRVHVKREHNPSEDVVAHVLATSDVPLMAHLTC
IGYRKANVVEIVRIFLDMGVRRFLALRGDPPRGVDADDVVGELRHADELVAVIREVEAEY
FGDGERHVHVAVAAYPAAIDHGREVEVLAAKQAAGADSAITQVFYDAEDYLALSRAARYC
GVALPILPGIIPLTDLRRLTRLEALSGVPVPEELRDALESAHGAGTVSTGIDATLRLATA
VLEGGAPGVHLYTFNRTRPALDVISQLRLGRILDGAAPDTRTQSEVRRAYLNATPGSSPL
RTGRMPVATRA
>A0A3D1AIS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MQPEIKSPFQQSLYNPEQFTITLELVPSRGGHNREHEHTLALAEKLAHDPRIQAVSITEN
AGGHAALSPEVLGREIQKLGLDVIVHFSSKDKNRNQMESLLFAWDRRGIRDLLVITGDYP
QEGYQGFAKPVFDLGSVHVLDLISRMNRGNYGPNQGRGAISPTSFLMGVALSPFKRLEAE
LLMQYAKLHRKAEQGADYIITQVGYDARKFHEVLQYIKLNNLNLPVLGNVFVPNLTVAAL
MRTGKIPGCIITEALYAEIRREATSLDKGKQARLLRAAKLLAILKGLGYAGAHLGGPGLT
YDNIDFILNTADSFADKWRELIPKMNYWHQDGFYLYKKDQATGLNTSETSVCAKRSTCLQ
TNYRLARLVHNLAFT
>A0A525CZX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKTESNLEKVLSAGHLAVTSECGPPRGASAQTVVDKAKYLEGVVDAVNITDNQTAMVRMS
SFAGSVLVKQQGMDPLLQMVTRDRNRLAMQADILGAYALGIDTMLCLSGDHTKFGDHAMA
ANVHDIDSIQLIQMVKGMRDEGTFQGGAEIKGVIPKMFIGAAANPFADPFELRVMRLAKK
IAAGADFIQTQCIFNVEKFERWMEGVRKMGLHEKCYIMAGITPMKSVGAAKYMKNRVPGM
DVPQELVDRMASVAKEDQPEEGIKICLETIERLKGVEGVAGFHIMAIDWEEKVEEIVKRA
GLYPRPQV
>A0A353NHW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKTESRLEKVLAAGHLAVTSECGPPRGCQPAHLIEKAKYLDGIVDAVNVTDNQTAMVRMS
SLAASFIIKQQGLNPLFQVTCRDRNRLAMQADIIGAYSMGIDTMLCLSGDHTKFGDHPMA
MNVHDIDSIQMIQMVKDMRDKGIFQGGAEIKGAPKMFIGAAANPFADPFELRVMRLAKKI
AAGADFIQTQCIFNVPKFEKWMEGVREKGLHKKCYILAGVTPCKSLGAAKYMANRVPGMD
VPKEIVDRMASVPKEKQAEEGVTICVETIEKLKKIEGVSGIHIMAIEWEEKVQEICERAG
LLPRPQV
>A0A5C5D6B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buttiauxella sp. B2|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRTIAQDYWNSGIRHIVALRGD
LPPGGGKPDMYASDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNYKQAHKFATMTNVRVPHWMAQMFE
GLDNDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPSI
>A0A6G2QWU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7804|TrEMBL
MALGTASTRTDRARTVRDMLATGRTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQS
>A0A8H2R284|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Urinicoccus massiliensis|TrEMBL
MIEFRGSKTQPLIFDGAMGTYLKQISPSDLTIEEYNIEKPAIIEEIHRQYIEAGAQAIKT
NTFGANPIQYDRNLCRTYLEAGAKIALKFQDRAEVYGSIGPMETPDLGDYLFVAEVLYQA
GIRKFLWETFPEADRLLEIIDSFCQDHGDTLHITSFAVFPSGETRLGVLAQEALEAADKN
PHVQAMGLNCISGPYHLVQLVKSLPTYQTPLGLMPNSGYPTMVDGRLQYKENPSYFSQAL
AQGLNYGLSYLGGCCGTDPSYILELSRHLKEVPGQAKSLKKEERVLKKTESNLKKKLKAG
KQVMVVEYDPPQEATRDYFKKLSLLRQMEVDAVTLADCPIGRPRMDASLTSLILKKDYGL
DSVVHMTCRDRNINAIKALLLGLSLEGIQDILLITGDPVPSVDREDVKAVFQFNSARLAA
FVKNLNRDLENPFTISGALNINAPNFDSELVKAKRKIKSGVELFFTQPIMGKNAIVQLRR
AQKELDVPILAGIMPLVSYRNAQYLHNQVSGMQVDQEVLDSFHEGLSREEGEEIGIGWAL
DFMNEIKDEVSGFYLITPFQRLQVIERLLKDYGQGKEK
>A0A1Y4BBC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. An3|TrEMBL
MKIRDYLKEHILLTDGAMGTYFDEQTGGEFVCSEEANLFQPDIIAGIHQSYIEAGAALIR
SNTFSANRKTYREIMSKHGQEADDAGFVRFVQKGYAIAREAAESAARDGKMVFAAADIGP
IYEDSESSQEEMRKEYREIADAFLEMGADIFVLETFPDERYVLFLAEYIRGKRPDAFVIG
QFSFVPTGYGRTGFHYKTVLKKAAGSGLLDGVGLNCGIGAAHMERFLRSWLEESGMPEQV
VLTALPNCGYPQIVRGHAVYSDSVAYFGEKAANLAELGAGILGGCCGTTPEYIREIAGKL
RGDTGKEMPKIRPVRRKHVTGAAEAGAKDKRTVEENVSETKALRQNTFLQKLKKGESVIA
VELDPPFDAQMDKLVNGARLLADTPADVITIADSPLARSRADALLTAVKIQQETGIPVMP
HLACRDRNRIAIRSGLLGAYVNDIRNVLIVTGDPVGRDERAFTKSVFDFNSIKLMEFLNS
LNGELFADDPFCYGGALNQNGARLDKIAERMKRKIDAGCQFFLTQPVYSEEELERLAFLQ
KETGAKILIGIMPLVSYRNALFIKNEMPGIHVPDEVLAQYSPDGSREEWEQTAAEISKTV
ITAGKDVGAGYYFMTPFHRVSLIKRIMETCVPE
>L0JWU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronococcus occultus SP4|TrEMBL
MCSRPHLYANGWQTVLSIRVPFVLATDRRRDPFGVRTRLMSGDIQSIPTAEGMVELLAEP
RFELMPFESIDEQLGHLPEGSEIAITTSPTLGLEATIEWSERASERGYEIVPHVAARYVE
DRDHLAEIARRLTEAGVTDIFVPGGDREEPAGEFESAYELLVALEDLPYEFAEIGVTGYP
EGHAFLDDETLAAAMNRKEPYATYVVTQLCYDPDAVLEWIDEIRTRGIDLPVEVGIPGVM
KYQRLFGISKKVGVGDSVRFLKKTSGIVGFLRQLVGSRGTYSPDTLLEGLAPYATDPYYG
IRGVHIYAFNQVPDLESWRAETLAKHR
>D8IB60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira pilosicoli (strain ATCC BAA-1826 / 95/1000)|TrEMBL
MNNNVENFIKKLENNNEYCFTLEISPQAKYDLSYIEEKINNSQIQNYADAFVVTDSPFAN
IKISPILAAIQLQQRLNNNKPFIATQTMRDKNSLALQNDLIGANYFDIRMILAVTGDAIA
NGNQKQAKGVFEGNSNLLIDIIKNLNKSKSLGEFTFKEPLKPIYPFCVINSYAKNDDSLK
VRLAKKANSGVKAIFTQPIYEVERLEFLLKCIDELPLKEKPILVPGFFPVLTYKTAYFIY
YKLSGSYIPEKWLSKLKKASDKSEEEERKTAIELSSKLFEDMLKIHKKMHIMSLNNYEFV
VDLLKNI
>A0A5E8D8X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. LW097|TrEMBL
MTATPTTPPADPDCRSSIPFSFELYPPKTDAATTALHVTIDALAAARPKFISVTYGASGS
SRTSSLDVLRYIRRATIVDPMAHLTCVGSSHAEASSLIREFLDAGVSSFLALRGDPPEGL
TENDAFLGDLHSAGELVQLIHRVQAERVPYQETPIPGLPRARAVKTEREHVRIAVAAFPN
GHPRSRSTAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPV
TSPGRLRRILELSGEELPAELSIQLEVEPTLEGQREIGISHAAALAEKLIAGGAPGLHLY
AFNQHETVLAVLDRAGALAPAQPVVSAHNPPPTHPSTSPADTRAGIHSTKDHY
>A0A2T5BW87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum imhoffii|TrEMBL
MSAPRVSFEFFPPQSLEAGFRLWDTAQKLATLEPEFVSVTYGAGGSTRALTHDAVKALHK
HFGLNVAAHLTCVGDSREDTLRVADGFAEVGVREIVALRGDPPRGEGGFTPRPDGFANSC
DLISALAQTGRFRIRVGAYPDPHPEARAPGDDVRWLKRKFAAGAHSAITQFFFEADTFFR
FRDACEKEGITGQIIPGILPIDNWAGVRKFARNCGAHVPAWLDDAFETARRDQREDLLAV
SLATELCTKLIEGGVGEFHFYTLNKAALTRDVCHALGVQPCARLEKVA
>A0A225MG95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidimonas nitroreducens|TrEMBL
MNPTQSVSLEFFPPRDIAAQEKLVRSAKQLLALQPSYVSVTFGAGGSTRSGTADTVRMMQ
NLGCDAAPHLSCIGSSRAVLAEILDAYKASGVRRIVALRGDMPSGMGGDAGELRYASDLV
RFIREHSGDWFHIEVAAYPEMHPQAQSTEQDLDHFAAKVQAGADGAITQYFFNVDAYFDF
VARAQAKGVNVPIVPGVMPITNHSQLLRFSNMCGAEVPRWIRLRLADFGDDRASIRAFGV
DVGVQMCQRLLDEGAPGLHFYTLNNAEVTMEINRQLRLEPAASH
>A0A2L2T5M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium venenatum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDAEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSVEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLERLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAVYPEWEATGLEAGGRAEAVNTRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWDHPKTRQDINDLFVKHIQGELSAIPWSE
EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PSNEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGSTETSPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNSIKDDYWLVNLIHHDY
VNRDALWDVLSS
>A0A447UNX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter koseri|TrEMBL
MPLTWSALLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRAITQFFFDVES
YLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFDGLDDDAETRK
LVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A543A9F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides albertanoniae|TrEMBL
MVTGRGRSLAELIRHGERSFSFEFFPPKDEAGEEQLWNAVRALEPYRPTFVSVTYGAGGS
TRDKTVAITGRIAAETELLPVAHLTCVGHTRDEVADILDAYAARGVAHVMALRGDPAEGP
RAEWTPTAGGLDYAVDVVRLAKERGDFRIGVAAFPEGHPGAESIEADADVLVAKARAGAE
FAVTQMFFRAEDYFGLVDRVRARGVDIPILPGIMPILNLAAIRRQSELIGAEVPEAIVER
ITAAGPEAADIRAEGIAAAAELCQELLDGGAPGLHFYTLNRSKATLEIFAKLNVTV
>A0A5C7ADS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gelidibacter salicanalis|TrEMBL
MKVTDHIKQSNGNTQFSFEILPPLKGQHIQSIFDNIDPLMEFKPPFIDVTYHREEYVFKE
QENGLLKKQVVKKRPGTVGICAAIQNKYKVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VMALRGDAVKNETYFRAEKEGHHYANELVNQINALNEGVYLDEELLNSSKTDFCVGVAAY
PEKHMEAPSLESDIHFLKKKIKNGAEYVVTQMFFDNQKYFDFVDKCRSEGITIPIIPGLK
PIATKKQLNLLPHRFHVDLPEALISEIIKCKDNSEVKQVGIEWCIQQSKELQKAGIPVLH
YYSMGKSDNIQTIASQIF
>A0A1R1SHJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sparsogenes DSM 40356|TrEMBL
MRDLLASGEQSYSFEFFAPKTEKGEQTLWNAIRRLEAVSPTFVSVTYGAGGSSREGTVRV
TERIATDTTLTPVAHLTAVNHSRAELRNIIGQYAGAGIRNMLALRGDPPGDPMGEWVRHP
DGVTYAAELVELIKESGDFCVGVAAFPEMHPRSTDWDADIRHFVDKCRAGADFAITQMFF
YAEDYLRLRDRVAAAGCTTPIIPEIMPVTNVRQIERFAQLSNAAFPPDLAERILAVKDDA
AAVRSIGIDYATQLCARLMAEEIPGLHFITLNHSPATLEIYENLGLHQRS
>A0A3E2B0V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Evtepia gabavorous|TrEMBL
MKLKDVWKKKEVTLSFEAFPPKKDSDFASVASAVEKIAQLKPDFMSVTYGAGGGTSAYTG
KIAQIVQAQGVTALAHLTCVSSDRDRIHHELDALCQAGIENILALRGDYPEGYDPSAPRD
YRYARDLVEEIRAYGGFSIGGACYPEGHVECPSQREDLRHLKEKVDCGVDFLVTQMFFDN
SALYSFLYRAQQVGITVPVLAGIMPVTNAAQMTRILSLSGTTLPNRFRMILDKFRERPDA
MKQAGIVYAAEQMVDLVANGVRGVHVYTMNKPDVAAGIAENLSKVLGRT
>A0A1Q7CEW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_2_20CM_2_57_6|TrEMBL
MKIFDFNERLKDSILIADGAMGSMLHEAVGTQRCFDELNSTEPEAVFRVHQAYIEAGAQI
IETNTFGANRFKLAPLGLADEVQRLNSRGVKIAREARESAAREVLIAGSIGPLGLGVQSR
HPADHEILDIFHEQALALEERGVDFYILETFSYIEELLLAIDAIRSFSGLPIVAQLTYAE
EGTTYGDLRPANAAEQLKNKNVQVIGANCTLGPQALLPILQELAAVDGLRVSGMPNAGFP
KREGDRIVYPKSSPEYFALFAREAAALGVRILGGCCGTTPAHIRAMAEAVKSLRPAKAHA
VVHSVATMAKPASLSEREPESKFWKKLQAKQFALCVEIDPPKGLSLDRIFEQVGKVMASK
KVDAIDINSGAMARVGMDALIVAGALEARGVETVPHLTTRDQNIIGLQAALLGAWTVGGV
RNILAITGDPPSVGDYPEISGVYEVDSVGLVKVLHRLNQGTDWAGKTLGGETNFTIGVAL
NPVADDLDNEIERFHAKVEAGAHFAMTQPLFDPEHWHAFLKKLGGKPSIPVCIGIWPLNS
YKQALRLNNEVPGIVIPERLLKSMEAAGASARDCGFKVARDMLAWSRTELAGAYLIPPFK
RYEEILEIL
>A0A7C3QDM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MLRFREALEAGRFVITAELEPPKGTDLTAVLGQAKPLVGLVQGVNVTDNQTAVMRMCPLA
VCKSLLDLGLDPIMQITVRDRNRMALQSDLLGAHALGIRNILSLTGDPMKVGDHKEAKPV
FDLESTQILEVIGYLNQGKDFERNNLVGATDLWGGAAASPDAPDSELELAKFEKKISCGA
KFFQTQGVYDSQSFEKFMSSVRKFKTKVLAGIIVLKSAKMAEYMNKNIPGIKVPEPLVEE
LRAATDKEQAVQVGIDIAVRTIRTIRNICDGVHIMAVGMRERVPEIIHKAGLV
>A0A7K3S1P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces parvus|TrEMBL
MALGIPSTRSDRAATIRELLDSGGRSYSFEFMPPRTADAEVGLWRAIRRLESLSPTFVSV
TYGAGGSTRGRTVNVTGRIAQETTLTPVAHLTAVDHSVAELRNILGHYADQGVRNILALR
GDPPGDPLGPWKRHPQGVEYAADLVRLIKESGDFCVGVAAFPEMHPRSPDWDSEIRHFVD
KCRAGADYAITQMFFDVETYLRFRDRLAALGCETPVIPEIMPVTTVRSLRRIPSLSTAAF
PPALAERMLAVEEDPKAVRALGIEHATEMCRRLIAEDAPGIHFMTMNFSQVTTEIYRNLG
LHAR
>A0A8G5NGZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPC
>A0A7X8LAF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epulopiscium sp|TrEMBL
MKIKDLFKTGPVISLEIFPPKPDMPVDTIFNTIHELADLHPGFISVTYGAGGSGKGHTVQ
IADVIQNQYGIEALAHLTCMNATPEEINDVLQRLQGVNVKNILALRGDPPQDKSFIPPKE
TPYQYAKDLILHIQDFGGFSIGAACYPEYHIEAQDPISDLKNLKEKVNSGVDFLITQLFL
DNQFFYDFKEKLDLMDISVPVSAGIMPVINKRQMERITKLCGASIPAKFKRILGKYEDNP
KALKEAGIVYATEQIIDLLSWGVDGIHLYTMNRAEVAREIIEPIAAIRDHLVTHP
>A0A6J4QQA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Rubrobacteraceae bacterium|TrEMBL
MPTQQSTEERQRANRRLAGFLRHPGYEVIPLQGTEESVVEHVPKDVALTVTASPGKGTWA
TVELAERLAGHGFGVAPHLSARLIRDRLELGEILQRLREAGIRNAFVVAGDIDEPAGEFE
DATGLLEVMSEIGHDLDEVGITGYPESHPKISDEMTIQAMYEKAPYATYIISQICFDPEV
TSDWARRVWSRGVKLPIRVGMPGYVNRQKLVRISAGIGLGESARFLHRQRNWLVKLLLPG
GYSPDRLIEGLKPGFADPNPNIQGLHIYTFNELEQTEAWRRKMLQRAELSS
>A0A7K7HSH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhegmatorhina hoffmannsi|TrEMBL
MVNEGQQSGSGSSSSRSDGGSSSGSESSKDNSRCSTPVLDTDRHERLREKMRRRQEAGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFVITQLFFRPETFLK
FMRDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYRVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7Y8H9Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MKSGSNLEKVLEGGYFAVTAEVGPPKGALSTVIKRKGELLKFHCDAMNVTDNQTAIVRMS
SWSGCILLKEMGIDPVMQMVVRDRNRIAIQSDILGAVALGIRNILCLSGDHQKFGNHPTA
KGVYDIDSIQLIQTLKTMRDDRKFMCGEDLSGELPIYIGAVENPFADPFEYRVHRLAKKV
KAGADFIQTQAVFDVKKFSKWMDMVRDHGLDKQVHILAGIIPIKSVGMARYMRDNVSGIS
VPDEIVIRMEEAKDAKEEGVKIAIEIIEQLKEIEGIHGIHIMAVAWEDIVPLIVERAGLL
PRPIL
>A0A7Y8DP11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas tolaasii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLHNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A022I4Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 1000160|TrEMBL
MSLFSQCLEQKQFCILVEYLCSNRDTLAVPLSLAGYPAMMTLADRVHSDEDSAPLELAQQ
YAPEIEKLLHFSGKGRDIQEFERFLNQAEQRGYHNLLLLSGDKLKNHNFGREIPAQRTRY
LESVSAVMAARQRHLFNIGVAFNPFKYTEAERDAQYLKLHKKIKAGADFLITQLGFDLDC
LQHSQSFISQHYKQFPLIACVMPLSLKRAQFMLKHQVAGLVIPAHIVHVLKSEYEADPVQ
AEANVYARCALQILICKHLGFVGVHLSACHKPQEQQKLEQFLKQYENWSLATCEKAWKQL
WKMDSGLELKPELATFSKPVPPAQIFKYKQMHLMHQLFFASHAALGVGRFIFKANFWNKA
RPDQLLLKMEHWSKHPLVGCESCGHCRLDDTLYICPETCPKGLANGPCGGTSLDRCEFGD
RECIHSVKARLAKHLGQTELLRSKLIPAISIETRYTSSWKNWFKHSESH
>A0A3M1QQ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
IEPREAEEGAVEPPPLAERSRLGAKLAAGRFVTSVEITPPRGADASGVLASCRTLKAAGI
DIVNIPDGPRASARMGAQHLAVLIEREVGIESCLHYTCRDRNLLAMQSDLLGLAALGIHN
LLIVTGDPPKMGDYPDATAVFDIDSVGLTHLANATNHGLDLGGNRIGPPTSFVIGVGANP
GAVNLEREVEHFHHKVEQGAEFAITQPVFDPEVLLRFLERIRPFRIPILAGIWPLVSYRN
AEFMAHEVPGVVVPEAVLERMRRASDRSREAARDEGIAIAREALAAVKGEVEGVQVSAPF
GRVELALPVIEAAADRLQGPP
>A0A1F9X250|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFOXYA2_FULL_39_19|TrEMBL
MKLKELFNSGKFVLTSEVGPPKGWNIDKTIHEAESLKGIVDAINVTDNQSSVMRFGSLAA
CHLIKDKGIEPVFQVTCRDRNRLALQSDILSAAGLGIENMLLLTGDHTTLGDHKDAKPVF
DLDSVSLIHTIKKLESGVDLANNKLDGEPPKFCIGAVVSPCAEPLEPQLMKMDRKIKAGV
EFFQTQAVYETDKFAKFMEKAKNSGIPVMAGIVILKSVGMAKFMNENVAGIHVPDNLIEE
LKKDKEKTKSGQTGIEIAARLIKDLKPYCQGIHLMPLGWDDKVPQILKLSGLI
>A0A558HIE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia crustatorum|TrEMBL
MEDGHAGAGSESEPESGLPGYSSSGRLEQVLKSGHFAITAELAPPDSANPQDVYARARLF
DGHVDAMNATDGSGANCHMSSVAMCALLARHGHEVVMQISCRDRNRIAIQGDILGGAALG
INNMLCLTGDGVQVGDHPQAKPVFDLDSLSLLEIVAGLRDKHAFASGRKLTDPPRVFLGA
AENPFAPPFDFRPHRLAKKIAAGAQFIQTQYCFDLPRFTAFMQRSQDLGLLEKCFILPGV
GPLASARTANWMRQHVPGVHIPDHIITRLEGAKDQKAEGRNICIEMIQQLREIEGVSGVH
IMAHRQEASVADIIQQSGVLRDRMPWTPSPEPTFKKEHAISAHAHD
>A0A2S6T4V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha5_Bin2|TrEMBL
MEYQSLLHKKLLDGNFVYTAETTPPDSADQEVILTKTKPLKYIADAVNLTDSPGAKVHMS
ALTAAIILAQNDIEPILQLTVRDRNRLALQGDLVGASALGVHNILCLSGDDPKIGDQPET
IAVNDIDSLTLVATADLMRRKGKFPSGRLIEPPPKFCIGGAEVPTEGKPNTEKILNKIKT
GINFFQTQYVFDKKILKEYMKVLDDVGILEKTFFIIGLGPFTSAKSAKWMNNNLFGVNVP
EKIIKRLEQSKDEKEESKKICLELIHHFKEINGVMGVHLMGHNKEEIIAEIIQESRKNKN
>Q1M8V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae (strain 3841)|TrEMBL
MMIAPQSESREEALLADLLSHYSIEVTSRDLQSLESMTATLQQGCEVFIAHLPKEDIGLL
VRAAAGLRDAGFVPIPHIVARNIRNRLELDTMLARLSEEAGVRHALVLGGDRDDAAGAFG
SSLELIETGLFQAYGIDRIAIACYPEGHPRIAGAILDAALTAKIDAAALAGLDVLLVSQF
LFDPKPLLNFARRLRERGVTAPLSVGIAGPASRTKLLKYALRCGVGASLRALRERSEIAR
NVLSGETPEELLMEIAAAQATEPDLGISGVHFFTFGDPAQSIRWAEQQVDR
>A0A1G6D2M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bauldia litoralis|TrEMBL
MQDKDNRPSRLLGADSSFRVSFEFFPPKTPAMEEKLWQSIERLAPLAPNFVSVTYGAGGS
TRERTHATVTRILKETPLRPAAHLTCVASKRDEVDEVVRGYGQAGVRHIVALRGDPVDGV
GTAYEPYPGGYANSAELVAGIKKVGDFEISVAAYPEKHPESRSLAADIDMLKRKVDAGAD
RAITQFFFDNDLYEAYVERVRAAGINIPIVPGIAPVHNFAQVARFAAGCGASVPDWLAQR
FEGLEDDPATRQLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGMRPAKPA
PTEAAA
>A0A1G4QSL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. NFACC05-1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRRLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A3E1SNE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella oxytoca|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRTIAKDYWDSGIRHIVALRGD
LPPGSGKPDMYAVDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1R1XYY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium culicis|TrEMBL
PPSLNDQIELVKSDDLMVKQIGIDFCCNQISTLTKECNILGFHFSTLNLENSLLAILTRS
GLLRTFNDPSDLSSLPSKFSASNTNSTLPVGGESATWDEYPNSRWGDARSPAFFNESIYG
QSSFINTDQLLQWGFPKSLDDINTLFSKYISGDIPSLPWTSDNINSSNSDFVISVLNYLP
KVGIWPMASQLAVDGAQSSDPEFGWGPANGYVYQRSFIEFFAIEPVALKILEHLKNNTKQ
DFSYYASKLNFDTNEPSILSNAVVNNASFDPSINSHLLEIESTALSWGVFPSSPVIQSAL
IDKLNFGYWSKEAIQLWRVWASQIGSFSKESKQFIDSVADSVYLINIVANDYKTPEKLFC
FLREEF
>A0A1Y3BLY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euroglyphus maynei|TrEMBL
DYDINDFQYAIDLVRFIRHNYGNYFTVVVAGYPIPHPESLDKNHDRQCLKEKVDAGADYI
ITQLFFRCEDYVQFVRECRMIGITVPIIPGICAINSYESNRYDPINKLYDN
>A0A6I7PBL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MTTRERFRQKLDTGTPLLLDGATGTELYNRGIFINRSFEEANLSNPALVLGLHRDYAMAG
AGALLTNSWGANQFKLAGHSLHDRTSEINVAAARLAREAAGEHLFVGGSVGPLGRPIEPW
GPTPAERAYEAFHLQIESLCRGGVDFIYLETFSDPAELEQAIRAAKAAAPCLPVAASLTI
DLSGDLLHGGSLEAAIQDADRWGADIVGLNCSVGPQPTLAAIERIRALTGRPLCVKPNAG
LPRQVEGRTIYMSTPEYVATFTRYFLQAGVQFVGGCCGTTPAHVKAMAQAYRHFMSTHAS
RRSAITGVEPQRRAAAPDAPEVQRIPFAAKSRWSSKLARGEKVYALELLPPGGVDIAPLL
EKTARVQRAGIDVINIPDGPRASSRMSTTLTAVMIEQRVGIETMLHYTCRDRNLIGMQSD
LLGIHAIGLRNVLLVTGDPPKIGNYPDATGVFDVDAIGLTRVAYRLNGGIDLGNRSIGEP
TALSIGVGVNPVHRNFDYEMQRFERKVEAGAEWAVTQPIFDAADMYRFLEYIGKRGITIP
IVAGIWPLTSLRNAQFMNNEVPGISIPEGVIKRMAEAGSKEDAVEAGVGIAAQLREQLEP
DVHGFQISAPFGRIDMALRVAGIEQP
>A0A533WCH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MRISFELNPPKIVKGDMFDLAKLNADMEAMADRASRLASLVSGIHLTDSVLGIPRVSSVT
AAGCIKNRVSTVKLNCSIRVRDRNFTSLCQAVSDAILIGIDSVLVLMGDDPVDGPSDSGL
RPSAAVRMLTKEGYSSSIKLDLSFPAKVQDRSAKSVRNKLEARPHSLVTQSISSVSDLGE
IVDLAKPHGIKVVAVVMVPVEKNRQSAAVIGLDWSEYERNPADFVRQAARIADTVLLTSP
NSFGSGLELLNELK
>A0A5E4S4B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea nosoerga|TrEMBL
MPGMRHERSPEKTTIMTQPSFSFEFFPPKTAEGAQKLRATRQQLFPLGPKFVSVTFGAGG
STQQGTLDTVVEIQREGVEAAPHLSCVGSTRENIRAILSTYQQHGIRHIVALRGDLPSGM
GEIGEFRYASELVEFIRAETGDWFHIEVAAYPEYHPQAKSPRLDLEHFANKVKAGANAAI
TQYFFNADAYFRFVDDASRLGVNVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEG
FGDDRESIRAFGLDVVSALCERLLAGGAPGLHFYTLNAASATKAMWQRLGL
>A0A1I6F1F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentzea waywayandensis|TrEMBL
MTSVVERLRGESPKFSVEFLPPRDAEDEKILWKAVRELEGLDPAFVSITYGAGGSRRDRT
IRATGRIAQETTLLPVAHLTAVEHSVAELRNVIGWYAAIGVRNILALRGDPPGDPMGEWV
AHPEGLNYADELVRLVRELGDFCVGVAAFPYGHPRSGDLDTDLKFLLRKLDAGADYAVAQ
LFHAPEPFLRMRDRVADAGCSAAILPGIMPMLSPRGLAKIVELSGADLPLDVSRRLEPYA
DDVAGFRATGIDIATEMCQRLLDEGVPALHFYTMNRSKATKEVLGRLGLVTRA
>A0A1F0Y2K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC078D09|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQPNFEVN
>A0A1Q5JNA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02460|TrEMBL
MALGTPSTRTDHARTVREMLATGATSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVKATQDIAAESTLTPVAHLTAVDHSVAELRNMVGQFADVGIRNILALR
GDPPGDPMGPWVEHPQGVKYAADLVRLIKEAGDFCVGVAAFPERHPRSEDWDTDIRHFVD
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCDTPIIPEVMPVTNVRQLERFSQLSDAKL
PDDLKERILAAKDDPAAVRSIGIDFATRFSAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A1W9PXS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfococcus sp. 4484_241|TrEMBL
MKAGSHLEKILRAGHFAFTGEIGPPRGTNVEDVRKKARFLKGNVDMANITDNQTAVVRMS
SWATSLIVMQEGVEPNYQMVCRDRNRLAMQADILGAYALGIRNILALSGDHQQFGDHPFA
KGVYDIDSIQLVNMIKTMRDEGKFQSGGDISGPPKMFIGAAANPFADPLEWRVHRLAKKI
EAGADFIQTQCIFNMARFREWIKQADDMGLTEKVYILAGITPMKSIGMARYMQKKVPGMD
VPEEIIKRLKGVDKKQVADEGIKIACEQIQELKETKGVAGVHLMAIEWEHKVPEIAERAG
MLPRPVVEDDEPSAQDDKKE
>A0A2K0WLE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella nygamai|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSI
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARADYLSSDSSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A0N0E7Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ahrensia marina|TrEMBL
MGGSVLSRTHDAASERNLRISFEFFPPKNDAMEKTLADTITKLAPLSPDFISVTYGAGGS
TRDPSKRTLAKVLEQAGIPAAAHLTCVGSKKEEVDEVIRDFASMGISRFVALRGDPETGM
GTQYVPTEGGYENAAALVAALKSHSDFDVSVAAYPEKHPESADFDADIDMLKRKVDNGAD
RAITQFFFDNDLYERYVERVRAAGINIPIVPGILPIHNFKAMSNFAQRCQTNVPAWLADR
FAGLEDDAQTHAMIATAIAADQVVDLVDRGVTDFHFYTMNRPDLVFALCKLLGIKGNDNP
AWAA
>A0A2N3G5H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Anoxymicrobium japonicum|TrEMBL
MSVENVWKELNVKNAKPSIQEVLESGKFLVSGEIGPPKGPDIEEVIEHIDLLKDKVHAMN
ITDNQSSVMRYPSLATALIILERGGEPNLQITCRDRNRMSLENELLFAYTRGVRSVLCLT
GDSVPVGDHKECKAVFDVESVQLLNIISAMEEGRDMGGNEMNAPVKFYKGAIFTPEAVPV
EPQMIKFEKKVEAGAQWMQTQAIYDMDNFAKFMKFARKYPVKIQAGLVLLTSAGMAKYMN
KNVPGVVVPDDL
>A0A1V6GUX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium ADurb.Bin072|TrEMBL
MLLKNILSCTPTTFSFEFFPPKTDTAWEHLFHTIADLMPLSPSWVSVTYGAGGTTRENTH
RLVVRLNKQTDLTVVSHLTCVASTREDIHAILDHYEANGIDNILALRGDPPAGQTRWTAA
PGGFRYASDLVSFIKDHFPRMCIGVAGFPEGHPETPNRLREIDYLKAKVDAGADFIITQL
FFDNRDFYDFRERCELAGITVPIIAGIMPIITRSGMIRMAELAAGSRFPAGLLRALNGAR
SPEDIERVGVKWATDQVRDLLENSARGIHFYTLNNARATLRIYEGLGLSGACRTGA
>A0A0M4GAF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 323|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEDLIKAVESCKNNNEVKQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A7L3T6B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rissa tridactyla|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A835BPH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Digitaria exilis|TrEMBL
MKVIEKIQKAAADGRTVFSFEYFPPKTDDGVDNLLERMDRMVAYGPTFCDITWGAGGSTA
DATLKIAKSMQNLVCVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFSCALNLVKHIKDKYDGYFGITVAGYPEAHPDEIQADGSATPEAYNRDLDYLK
RKVDAGADFIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYNGFKRMTTFCKTK
IPAEIIAALDPIKENDEAVKAYGIQLGTDMCKKILASGIKTLHLYTLNMDKSALEILKVI
LMANRPKSYITRTAHWNQYPHGRWGDSGNKYAQLTDDMVISDSFYSVYIFLALLLFLCNI
LDMFIAQCNYLFIFEQFTRPSGRSKKLNDEWVAPLKSAEDIKERFTNFYQGKLTSFPWSE
SYGLQQKIIDDQLVKINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCT
EEKLGQLIKKIKEAFPSLTYMALGKNGKSFTNIPANAVNAVTWGVFPGKEIIQPTVVESA
SFKFWMKEAFEIWAHLFGKDDSSALKTVLHDTPKLEHSTALDNYYLVSLVDNDYVRGNLF
AAFKDI
>A0A837B2E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 2-460-02_S1_C1|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6I6RCU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas veronii|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMRQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A5C8DLQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afipia sp|TrEMBL
MTSDTAAPAETHGQKRPAISFEFFPPKTEEMERSLWEVINRLAPLTPNFVSVTYGAGGST
RERTHSTIARILGETKLTPAAHLTCVAASKADIDDVVARYHDVGVRHIVALRGDPTSGIG
TQYTAHPDGYHQSSDLVASIKRNHPDMEVSVSAYPEKHPESASIDADIDALKAKVDAGAT
RAITQFFFDNDLYYRYLDRVRSAGITIPIVPGILPVQNFKLAKNFATRAGATIPGWLEAK
FEGLDDDADTRRLVAATVAAGQVQKLAKQGVENFHFYTMNRADLVFAISHLLGIRPAGAQ
KAA
>A0A494TEU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter cryaerophilus D2610|TrEMBL
MFETLISKLQEDKYLTLETTPQHEPSMHNIVEKIKKFKIDSKVDGFTCTDNPLAKLKYNS
LFAALKLQQEFKKPVIATMTMRDRNKIALQSDLLGANDFDIRAILALTGDPANMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFAVVNAYAKNFGSLEKKMHLKI
QNGAVGVITQPVFDIENVKKLLENFENAKENVEGDKRKAQLIFGVFPITKLRTALFLSAQ
VPGIHVPQFWIDELEKAHNISEEEEYKVGMQLSKNLFDEINRIHPKIHLMTANNKFEVAS
EILA
>A0A413IN76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricimonas virosa|TrEMBL
MKVIDILNNTDKPVFSFELVPPLKGGDINKIYEAIEPLIALAPPFINITFHRDEVVYREY
PDGTIKKVTVTKRPGSVALAAAIMRRYNVDMVPHIVCGGATRHKIENELIDLNFLDIENV
MALRGDPIPGERFFTPEEGGHLYSCELVEQITRMNHGQYLDDTLTDTVPTNFCIGVAGYP
EKHYEAPNQACDIENLKKKVDAGANYIVTQMFFDNAKFFQFVDKCRAQGINVPIIPGLKP
ISTFKHLEMLPRTFSIDIPHELVKEIRSCKNNKEINQVGIKWCVAQSKELIAHGVPAVHY
YTMGKSENIQEIVKQVF
>A0A1A6AJ42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium ragsdalei P11|TrEMBL
MSLLKEAFEKGEFAVTAEMAPPKGTDLSHLIECAKKIKGRVHGVNVTDFQSATLKATSLA
TCKVLKDAGLEPVFQITGRDRNRIAIQGELLSAGVFEIENVLALTGDYTATGDHPGAKPV
YDLDSVGILQVASILNGGKDMGGTDLKGKPDFFLGACVTPRYDPLELQVIKMKKKIKAGA
KFFQTQAVYDMETLKKFKEETKAQGVDAKVMVGIIPLKSAGMAKYMNKNVPGIFVPDELI
DRMKNAEDKVQEGIKIAGEFIKAVKESGLCDGVHIMAIGAEENVPLILDEAGL
>A0A510X4X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas pacifica|TrEMBL
MNMTIGVDHDKRVSDGLGHSSSGRLERVLRAGQFAVTAELAPPDSANPEEVYARARVFDG
YVDAMNATDGSGANCHMSSVAMCALLSRRGYETVMQVSCRDRNRIAIQGDVLGGAALGIN
NILCLTGDGVQVGDHPQAKPVFDLDSMSLLETVAGLRDKQVFASGRALSDPPRVFLGAAE
NPFVPPHGFRPHRLAKKIAAGAQFIQTQYCFDLSRFRAFMDQSRDLGLLDKCFILPGVGP
LASARTAEWMRRHVPGVHIPDAIIRRLEGARDQRVEGRNICIELIQQLREIEGVSGVHVM
AHRQEAYVADIIEKSGVLGDRAPWSPSCNKALEKQHA
>A0A431JJF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium|TrEMBL
MTISVNQLEEAQVALGAPLYADVGGDLDVSFEFFPPKTEKMDEQLWEAVRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATKAEIDQVAEEYWAAGVRHIVA
LRGDPPAAGAKFESHPGGYENAAALVAGLKRLHPFEISVAAYPECHPDSASVAADIDNLK
AKLDAGATRAITQFFHEPETFFRYRDKVAAAGITAEIVPGIMPVTNFASVVRMSKMCGTE
VPAWLARLFDGLEDHPAARQLVAATLAAELSRKLYAGGVKSLHFYTLNKAELSFAICHLL
GVRAKPVQDAAAA
>T0W266|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris TIFN1|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAIAHLPAAYLDKTQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSLISSLFKINT
>T0K219|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum gloeosporioides (strain Cg-14)|TrEMBL
MHIKAMLDETRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREHEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDADNFIRWVGKVRERGITIPIIPGIMPIATYASFLRRAKHMNCRVPDDWMAAL
EPVKNDDVAVREIGKGLVANMCRKIIAAGIHHLHFYTMNLAQATRMVLEELDYMPSSERP
LKHALPWKQSLGLGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSIKDVANIFVRYLETEIDNLPWSEAPLTSEADGIREELIG
LNKRGLLTINSQPAVDGVKSSHPVHGWGPPNGYVYQKAYLELLVHPELFPEIVARIEKNP
DMTYYATTKNGALTYNASSDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGTDW
ARCFEAGTPSRVLIDRIMNEWYLINIVNNDFHQKTALFDLLDGLSVQEYTDIPSEPQASG
ETELQNGTTGAAVTA
>A0A154PG15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dufourea novaeangliae|TrEMBL
MAKICNFKVPENILNVLQSIQYDDDKIRNYGVELAISIIKDVISSGTTCGFHLFTLNSMR
MRCRRMSDELTEELVELGARAPRGQLDSWFDGNKKEEGP
>A0A7Z1YDP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. PAMC27889|TrEMBL
MSKPAFSFEFFPAKTDQGREKLLSTFDELNTLSPTYFSVTYGAGGSTRSRTLDIVQALST
RGDTDIAPHMSCIGDDKSEIAELLEHYKSLGINRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFRIEVAAYPEMHPQARSFEFDVDNLVNKFQAGANAAITQFFYNADSYLYLR
DTLEKRGINTIDQPLVAGIMPITNSSNLIRFADSCGADIPRYVRKQLFDYGDDSKAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVEALGLTT
>A0A8B2XQB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pasteurianus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADTIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAREAAGDDAFVLGTVGALRGLKQCNLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEVELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKEANFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDGLADLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALEHFKGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A6P6PYX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carassius auratus|TrEMBL
MVNQRVDIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKISAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIVTQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQFESPLFAQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDND
AAIRNYGIHQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAV
SAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSK
SPKEALLQMWGEELMSEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDEL
EKVNRRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKK
YEPRVNYHIVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALW
IEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPQETQE
E
>A0A6A5YH61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lophiotrema nucula|TrEMBL
MEKITDKIAGLGKDANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
AQKSLELAEICQRQLGLTTCLHLTCTNMSRSLVDEALEQAKVLGIRNILALRGDAPRSEE
YREEGAPPEEDSNKDFTWAIDLVRYIRKQYGDYFCIGVAAYPEGHSDESHPEHQSVEHDL
PYLIEKVKAGADFLMTQLFFDVEAYDRAEKLWREHESGALKTIPIIPGLMPIQSYAILRR
TTKLSHAKLPADILARLDAVKGDDELVKQVGVKILSEIVEHLQSRPDTCRRGFHFYTLNL
EKAVSHIVEDTKLIPPTFIEDDEEAIVDMGPGSPIPISISPPEGGSSRGRRRLSSVNSGP
RNRVVVSRPSKSSNASYEAPETEAGIPKGPINSRANTLAISEGEGSLGREATWDDFPNGR
WGDARSPAFGEIDGYGPTLHVSTPQALKLWGHPVERADISSIFKKHLIGELEALPWSEQG
LSPETSTISKELLALIDKGWWSVASQPAVNGVKSTDSVFGWGPKNGYVFQKPFIELFIPS
KDFHKLLPRLTAHEQITYFAGNAAGDFEASDENGVNPVTWGTFAGKEIITPTIIESVSFK
SWLDEAYSIWREWQRIYPPRSQTAKLLGEIREDVWLVNIIWGDFVEGQGLWEFLMAD
>A0A2C5Z3H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps camponoti-rufipedis|TrEMBL
MHIKQMLAEAADGRKPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQSVCGLETCMHLTCTDMGLDKVNEALSKAYKAGCTNILALRGDPPRDQQT
WTATDDGFQYARDLVKHIRDTYGNHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDLGASF
IVTQMFYDADNFVRWLGRVRERGIHVPVIPGIMPIATYASFIRRANHMQCTVPPRWMEVL
EPVKNDDVAVRELGKTLVADMCRKLLANGVVHLHFYTMNLAQATRMVLDELDWAPCAERP
LHHALPWKQSKALGRRDEDVRPIFWRNRNTSSTPTASA
>A0A0T5XB11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetomicrobium hydrogeniformans ATCC BAA-1850|TrEMBL
MKIKDIFERKKFVFSFEIFPPKPTTPLDRIYSTLDDLKGPSPDFISVTYGAGGSTRDRSP
QIAIDVKNVYDIESLAHLTCIGSTRDEVVGVVDLLLESGVHNILALRGDPPQEAVSPFVG
GDFSHAIDLVKFLRERYGEKIAIGGAAYPEGHIECDDPIKDLHYLKQKVDAGVDFLVTQL
FFDNELFYRFVERTSIAGIEVPISAGIMPVVNKNQIERIVTLCGASLPKKFVRILHRYAD
DPRSLEEAGIAYATDQIVDLIASGVRGIHLYTMNKAHVARKITSNIETLREGFVNDKNNE
EALL
>A0A374A145|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF12-41|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPDLCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A1G3FTG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium GWF1_65_7|TrEMBL
APLKPTFCSVTYGAGGTTRKLTHEAVTTIGKNYGLNVAAHLTCVEATKAETLEIAEAYAA
AGVREIVALRGDAPKGATRFTPHPEGFASSVELIEALAATGKFTLRVGAYPEPHPDAADT
LADVRWLKRKIDAGASSAITQFFFEAETFLRFRDLCAKEGITAPIIPGILPIENFAGVKK
FATRCGSAVPQWLDDAFTTAKRDGREELLSVALCTELCDTLISEGVEDLHFYTLNRPHLS
RDVCHALGITPEVALEKVA
>A0A0B8QJI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio ishigakensis|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLVAAPHLTCIDASRDELINIADDYWSNGIKSIVALRGD
IPPGGGKPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRSVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMSQQFE
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQTA
>A0A7C4CT21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidilobales archaeon|TrEMBL
MFLNTCPKRMINGPCGGYRDTVCEDERLTCVWIMAYYTAIKRGTVDRMFTLKLDSGFKIN
NYYPIPRRPRGAVEKILGGRVFMVYEYTPKPYSSPLNIPSELRGIASIYDGVDFVDNPGG
YPIPSSLPYASIAKNSYRDMHVSIQLTARNRDRSQIASEILAASLSGIDAIVATTGDLDD
SGKGVWDLDAPRIIYLARLILDLGLDHLGRRVGLGGEGMAIACSVNINARPLEPEILKLR
VKRRAGAEIVITQPVFEPEILGRFRRMTKDLLGEEMPMILGIIPIMSRKIASFFQNKVGI
KIPEKISKILSSERIDKEELLKTNIEVIENIAREVAHNAFYISAFGDHKLGYEIGRTIRR
ALS
>A0A3B5A203|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stegastes partitus|TrEMBL
MVNQVQRGDGNWSGKSDSSGASNSGGESSKESSRCSTPVLDADRADRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGSRGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPLGVDWEEEEEGFNYAID
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGANIQLFFRADTFLKFL
DDCRTIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNYGIQ
QAVDMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVE
DVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLQM
WGEELMNEESVNEIFTCYITAQPNRRGHKVLCLPWNDEPLAPETNLLKDELEKVNRRGVL
TINSQPSINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYQI
VNVQGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYE
DESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPLEPLSDGTVSE
>A0A6I3WDT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas spelaei|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKSAGIQRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A8H8DD22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida metapsilosis|TrEMBL
MSKVIDLIQSLGPDEKFVSFEFFPPKTDSGFRNLLARLNRLSAFNPLFITVTWGAGGSTS
EKSLDLAATCQKKIGATTVLHLTCTNTNKEVIDDALKRAKENGIRNILALRGDPPRTEEY
WTPNCQFKNAVDLVKYIRQVYGDYFCIGVAAYPEGHVDGADISNQNPRKDIPYLVEKIRA
GADFIITQLFFDVNKFITFEKLIQQTPELKDVPLIPGLMPVTTHRVFTRATKLSHATIPT
AIYNQFEDIKNDDDAVKAVGVDLLCQIINKIDESTNIKGYHFYTLNLEKAVASILNKSAV
LRPILEQPSPVFGNEDAIASDSDDEDAVPVPASAPLQQRKHRKSSAVEPLTQKAVVEISR
GLGAFGKEAIWDDFPNGRFGDSNSPAYGEIDGYGPNLKIYDKSEAIAKWGSPESIDDLSR
IFTSYLSGKIDVIPWADVQLSPETALIQEELFELNEKGWFSVASQPAVNGCKSTDNIFGW
GPSNGIVYQKSFVELFMPAHDWEKLGSKLDSSTTYYVGTRTGKIKSNLPIEQDFAKSKSA
VTWGVFPQKEILQPTVIDYESFKAWNEEAFLLWLEWARCYKKDSKSFKLLNSIYNDYVLV
SLVHHDFPKEDALWQQLLQ
>A0A2S7TKK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum sp. SG-28|TrEMBL
MKVTEHLEKAKGSTLFSFEIVPPQKGQNIQELYDNIDPLMEFKPPFIDVTTSREEYVYIP
KENGLLDKKITRMRPGTVGICASLKYKYNVDAIPHVLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDARKDQQYFEASNGGNRYATDLVKQINDLNKGKYLHEIIETPYKANFCVGVAGY
PEKHLESPSLESDLKRLKEKVAAGADYVVTQMFFDNQKYFNFVKKAREMGIDVPIIPGIK
PIAVKRHLQVLPQIFRLDLPQDLVNAIEACRHNKEIRQVGIEWAIQQSKELIEAGVPVVH
YYSMGKSSNIKAIAKELF
>A0A059G522|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas oceanitis SCH89|TrEMBL
MSSLSIANRQKDAAPSVSFEFFPPKSEAMATRLWETVQRLEPMSPEFVSVTYGAGGSTRE
RTHDTVKRIASDTALRPAAHLTCVSATKAEVLDVADSYAAAGVHHIVALRGDPPEGMGAA
FTPHPDGFANSVELIEALSEAGKFEISVSCYPEPHPNSRGWDEDLAFLKAKQDAGAKRAI
TQFFFEPDTYLRFVEKARAKGITMPLVPGIMLQPNFAGLKRMASMVQASVPAWLDRLYDG
LDSDDETRDLVTATVAAELCHKLADEGVSDFHFYTLNRAGLALSTCRLLGMKPKPVQAA
>A0A2T6M156|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. GV027|TrEMBL
MTRYDQLREARTALDTPLFAGLPGDIRVSFEFFPPKTDALMAQLWDVVQTLAPLQPEFVS
VTYGAGGSTRDRTHDTVARIIREARLPAAAHLTCVDASKAEIRAVAEGYWEAGVRHIVAL
RGDMGAPGVPFTPHPDGYANAAELVAGLKAIAPFDISVAAYPESHPDSPSQEADIDNLKR
KLDAGASRAISQFFFEPETFFRFQDKLAAAGIDAPVLPGILPVSNFAQTRKFAAACGAAL
PAWLESLFAGLDTHPASRQLVAATVSAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
RRPHGAAGLENAA
>A0A425Y2V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylomarina euxinus|TrEMBL
MKVIDHINQAIENRTTHFSFELLPPRKGNSIYKVFDTIDKLKEFDPKYINITSHCDEVIF
AESANGTFQKKLTNKRPGTVAVAAAIKNKYKVTVVPHVICQGFTPEETENALIDLNFLDI
QDLLLLKGDSSKRHEFAAKESGHHYAIDLIEQVNQINRGEYLDGTHTEAFDTPFSYGVAG
YPEKHEEAPNLDSDIYFLKKKVDAGADYIVTQMFFDNQKFFEFEKKIRAAGITVPLIPGI
KPISALSQLNLLPQVFKVDIPEVLAAEVRKCKTNEQVKALGTEWGIHQSKELIKHGVPSL
HFYSFMASNCVRDIAKVIF
>A0A0L8QHN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces varsoviensis|TrEMBL
MALGTPSTRTDRARTVRDLLASGERSYSFEFMAPKTEKGERTLWNAIRRVEAVAPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSLTELRNVIGQYADAGIRNMLALR
GDPPGDPLGDWVPHPEGVTYAAELVRLIKESGDFCVGVAAYPEMHPRSTDWDTDIRHFVD
KCRAGADFAITQMFFNAEDYLRLRDRVAAASCATPIIPEIMPVTNVRQIERFAQLSNAVF
PAELANRILAVKDDPAAVRSIGIEYATELCARLMAEDIPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A658AJ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MSDSTTPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADA
>S0FZD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotignum phosphitoxidans DSM 13687|TrEMBL
MSFVISDTQKFVTTIEVVPPAGNDPAALLDKLAAISDLDFDGFSVATNPVAKPRMSAMVF
CHLLHQKTGKPAILHLTVRDHNLLGLQAELWGAKALGIDTLIAVTGDPSAGRQKDGATAV
NDVNVYQLITLANESGLTTGAVLDFRPERNGLKNEVKRLEKKVAAGSRFIVTQPVYDEPT
AKTLADACAHLPVPKLMGILPLLSFRHATFLHDKVDGIAVPDALRREMETSADPVRTGTI
QAKHMLEIAKLYFSGACVMPPFERFEILKEIL
>A0A7W1BUE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
IVGDGGMGTLVTSAVARLRCPEEANLRAPESVLSLHLGFIRAGAELIETNTFGANRHKLR
TQYLENEVKAINEAAVKIARDAREVSGRDVFIAGSIGPLGEIGARRDDRAALFTEQAELL
EGRGVDLFLVETFYELDELETAIAAVRSVSSLPIVALLTFDEDAHTLGGVSAARAASALE
DLDVAAIGANHGLGLQAALRALEQMSGSGKPLAALPNVGLASLAGQRVIFPHTTPEYFAD
FAAHAQELGARIIGGCCGTTPTQIAAIRDAVDEGRRSSVPMVVRERQLVVAATEPERETL
LQQKLRSGEFVVSVEIDPPRGGRAQAMLDLARTLRDSGHVDVVDVNDNPRARARMSGLMA
SATIERVAGIETIPHLTPRDSSIAGLESMLLGAHAEGIRNVLAVTGDPPEAGDYPGSGGV
YEVDSIGLSRIITQMNAGEDFNGREIDAPTSFFLGVAVNPAADDLGYELERFEQKLEAGA
KFAMTQVLFDFAYLDAFFERLGRPCPIPLLIGIFYVKSHQLALRLHNEVPGIVVPEHVLA
RLRDAGSKAGEVGLAIARELLEESRARAAGAYVIPPFRQPLAALELFT
>A0A6L6AJG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSDGRGLSMRDLLARGERSFSFEFFPPKDEAGEEQLWQAITDLEPYGPTFVSVTYGAGGT
TRDRTVAITERIARETSMLPVAHLTCVGHTVEELTTILDDLSRAGVHHVMALRGDPPSGP
GSPWTPTEGGLTYANELVALIRERADMRIGVAAFPEGHVDAVDLETDARVLKAKHDAGAE
FAVTDMVLRASDYIGLVERARAVGADLPIIPGIMPILNLRSMQRMVEFSRRQLPEEITSR
LEPLADEPERLRAEGIAIATELCRDLLEAGAPGLHFYTLNRSKATREIFANLRITV
>A0A6I3G0G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVLGTSYSFEFFPPKDAEGEERLWHAIEGLKSIAPDFVSVTYGAGGSTRDRSIRIAREIT
DRTGIPTVAHITCVGSTRDELLEILHSYQDAKITSILALRGDPVGGPLAPWIPTENGFAH
ADQLVELARDCGGFTIGVAAFPDGHPSSGGDFNKDIDVLVRKEQLGATFATTQFFFDVQA
YVNLVERLAKRGSSLTIIPGILPVTNVKLLHRMAELGGTPVPPDIAKAFADVESDTQAVR
NLGVEIATKLCQELLEAGAPGLHFYTMNSSTATVEIYRRITNAQ
>A0A7X9KGF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSTQRSLIADARYEVIPMKNLESQIEFIPTGASVSVTCSPAKGQQATLDLAARIVDLGHV
TVPHLSARLAEDAAAVKRLGAFCRDHGLTEVFLVAGDAPEPVGPYDGVVSFLRDFLDTDH
GLSRIGVTAYPDGHALIEQSVVHEALHAKQALLEEAGIPGFASTQMCFDLTTWKDWAVAE
RAAGLKLPLHIGVPGVIDRTKLFTMGMRLGIGNSMRFVKKNGGV
>A0A7W0UR39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPLAGAEEAVLEHVPTEVKVTVTTSPRKGLEPTLELAEKLAGRGYAVVPHLAARHVRDRV
HLAELVERVHRFGASDVLVMAGDAAQPAGEFDGSAPLLRALAELGHPFQDVGITGYPESH
AFISDEATIRSMFEKAEFATYIVSQICFDPQVTAAWVAAVWERGTLLPIHLGLPGAVPRS
KLLRVSARVGVGDSIRFLRSHGGWLRRALRGNFDPEPLVAGLEESLRQPRQNVAGFHIFT
FNA
>A0A7K0WA77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSDYRLLRQANQADGTAASVIEALQTRASLNQQTLSFEFFPPKDDEAAAALWKHYETLIE
AEPDFVSVTYGAGGSSRETSLAVVDRMAKDVLTVGHLTCVGATAESSRETIKHFEQAGVS
SILALRGDPPLNDPQVLAVGEMKTALDLVQLAKSVSSLEIGVAAFPEVHPESPSMQHDAE
VLRLKQDAGATFAMTQLFFSVEAYLRLVSAAESAGSVMPIVPGLMPISNAAKVLRMAQMS
GADVPRELLEKLENASESDARVIGMDYSVRLANDLLQAGAPGLHIFTLNYSKAALEVARG
CGLA
>A0A524KVR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MSNDFLGLLKEGVVLFDGAIGTVLYEHGVFINRCFDEINLSNPSLVEKIHEQYVRAGADV
IETNTFGANRVKLKLHGLDSKLEEINIQGVRLARNAASGKAFVAGSMGPLGIRIEPWAPT
SNEEAGEFFREQALALLEGGVDLFILETFSDLNEIHQAIKGIRQVCDLPVISQMTLQKDG
LGLFGTEPGEFALRLSEWGSDVVGVNCSVGPRITLEAIEKMAETVETYLSAQPNAGIPQN
VDGRNIYLVSPEYMAEYSRRFIKSGASIVGGCCGTTPEHTRAMRNALSSIKPAKHHVTVN
IIEAASESSISEDRSISLAEKSLLASKFAKGKFIRMVEMVPPRGCDPSKIIASAKDLRDR
GIDAVNIPDSPRASSRMSPIAMAVLIEKNTGMETVLHYCCRDRNILGMQSDILGAHALGL
RNILIITGDPVKAGDYPDATSVFDIDSIGLTNVIYGLNRGRDIGGHDFGAPTSFLVGVGV
NPGAADFELEIDRLHWKVDAG
>A0A6G0A7N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAKISDMLTAGRTFSFEFFPPRSDEAERQLEKALHELTPLQPDYVSVTYGAGGSTKERTR
DIVIEICRDRAFPAMAHLTCMGHTRAELLELLADYAANGVHNILALAGDPPADGSAPTGD
FTYATELIELIREVGDFCVGVAAHPELHPRSPSRESDRRYLAAKLELADFGISQFFFDNR
DYFSMLDELASLGCETPVLPGVMPVVNPTSIARFADMNKAKRTSELWDRFEVLADQPAAL
MDLAVEVAAEQCRELLDAGAPGVHLYTLNRSEAALRIFDRLDLLPPRGR
>A0A6I2Y788|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDTLLAERTEPLFSFEFFPPKTEEGEKNLLEAVAALRELDPAFVSVTYGAGGSTRDKT
LEVVDTIKKEYGLEAMAHFTCVAATVDELRATLDKLSDIGVENVLALRGDMPDGGDWTAT
EGGLSYSSELVELINREYPQFAIGAACFPETHVAATSPEDDLAHLAEKVTAGTDLLVTQL
FFDNAVYFDFVDRARAAGITVPIVPGVLPITNIAQLTRITSLCGAALSHDLMAELNARAD
DPEAVHQFGVAYATLQCAELLAGGAPGIHFYTLNRSPATRAILSALRLHRPWENSKS
>A0A6L5ZTK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNSKLRGTTFSLEFFPPKDEAGESRLWLALSQLQPLAPDFVSVTYGAGGSTRDRTIRVTS
EITKRTSIPTVAHLTCVGATRDELVEILNQFKNSGIDSILALRGDPTGGPTAPWQMIPNG
LNYARELVELAVGMGFKAGVGAYPDGHPASNHDLAKDIEVLLAKEKAGATFATTQFFFEI
DKWQAIVDKLAKAGSKLPVLAGILPITNVKQLNRMVELSGMKVPTAIADQFSKYADDLEA
TKEIGIEIATNLGAQLLKRGVPGLHFYTMNSAQSTVAIAKNLGLIK
>A0A6I3BM58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRPTISFEFFPPKDDQGESNLHATIEALKKFNPDFVTLTYGAGGSTRDRTVRIAAEIILR
HQIPTMAHLTCVGSTRDELTEILREYTKAGVKDLLALRGDPVGGPTSEWISTPGGFDYAD
QLVDLATKVGGFNVGVAAFPDVHPASHGNFQQDIDVLLRKEELGATFAITQFVFDSERYA
QLLFTLRDRGSKLTLYPGIMPVTNYMQIVRMLELSGGTMPSATRLKFARYQNDPASIKEL
GIEVAARICEEVFEVGAEGFHFYTLNSALATSQVVSALSMLNFSS
>A0A6I3IDL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAHISDLLAAGRTCSFEFFPPKTDDAARALEQTIAELAPLDPSFISVTYGAGGSTRERTR
DVVINIERNLGITAMAHLTCVGHTRAQLDSLLDEYKAAGVSNILALAGDPIVDDNGVVAE
SEFEFAMELV
>A0A847MES3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MSWLKQVLQSGYFAVTAEVGPPKGSDLQVIRKKCDLLKGFVDAVNITDNQTAIVRMSSFA
SCLIAKEQGIEPVMQMVTRDRNRIALQSDFLGACALGIPNLLCLTGDHQSMGNHPQSKNV
YDIDSIQLLQMLKNMRDQKVFQNGEEVKGEIQVFLGAGESPFADPLEFRALRLAKKIAAG
AEFIQTQAIFDIDIFTRWMEEVRNLGLHKKSFILAGVIPVKSAKALRYMKNEVPGVVIPN
SLIERMETAADQKAEGVEVCIETIQKVSKIEGVSGVHIMAIAWESIVPEIVQRSGLLPRP
VKGEITS
>A0A3D3BRA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGAFNDLVASRERPIVTAEFPSMDGGDLDTVAEAVDRFQPYVDAVNITDNPAAHAHASNV
SMAIAVKQLGLEPIMQVVCRDKNRLAIQADVVGAQMHGVTSFCALTGDDVTAGDEPEARR
VFDIDGPQLVSIMRTLSDGTYLSGRSLKRHRELLIGAVENPFAPPAHVRVRRARMKVDSG
ARFLQLQIGYEPEKLEAFVQGCVDNGVCRDAAVLPTVILTKSAGALRFMESSVPGIHVPG
DVIDRIASAVDPLEESYQLAREQAAQALSLPGIAGIHITDFRHDDSVHRLVHDLRLGPAF
STGATTTHAQTA
>A0A1G9L1A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus oleiagri|TrEMBL
MGELLEHAARPLYSFEFFPPRTAEEEPVLLRAVEALAPLNPDFVSVTYGATGSRRDRTIH
ATRRIAEIGNPMTVGHLTCVAQSKADIAAALHEYAEAGVRNILAVRGDMPGGGPWEPHRD
GLRNATELVEFVKGEGDFCVGVAAFVQPHPDSNDLDLDARILLEKVEAGAEFAITQLFFE
TRDYFDLVERVRGLGCDVPIIAGLMPLTVITQIERFQALSGQPLPQSFVDRLRAAPPEEV
RAVGLQHTVDMCNELIDGGAAGLQFFTQNRSKATREVLAQVRAQRDALISPA
>A0A2N5KK15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MIGDHAEASKGRRGGDGTAPLRGLAHPRYEIVPIEGALYRAMHLPEGAEVSVTCSPTLGI
GNTISLAEELLARGFRVVPHLAARLVEGEAHLREVLGRLEEGGLRDVFVVGGDSKTPAGP
FASGLELLGAMTRLPSGIERVGVPAYPEGHPIVAREELMRALLAKQPFASYAVTQICFDP
GTILRWLAEARERGLRLPVYVGVPGVVDRKKLFRISLKIGLGDSVRFLKKQTGLAGRLLR
PGGYSPDALIEGLYPYVGDPDYGIRGFHINTFNHVRQTERWRLRMLRSTNTEGVSDGTGR
AALASVRDKE
>A0A2E5EVR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSPISQIYQSESPVFSFEFFPPKTASGQANLAEKLPEFLALNPGYISITYGAGGGTRDLT
KSLLLSLGDQVNRVAHLTCVNHTRQDIYHILDDYKQHGISAIMALRGDFPKNEGPTLTQE
IPHAVDLVTLIRERYPHMAIGVAGFPEGHPECPNRLLEMDYLKAKVDAGATYICTQLFFD
NRDFFDFRDRCHLAGITCPIIPAVMNISSKKGLHRMAELAAGARYPSALLAQIQGAHSDT
DIEAIGLDWTCNQVAELLKEGVPGIHFYTLNNVSHVQHIFKHLSLG
>A0A3P1TAZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachnia propionica|TrEMBL
MQSVADLLANSSSPLLSFEFFPPRSEEERPRFDTSVARLAAYRPAFLSVTYGASGSTRDR
TVAATAALAETRHATVVGHLTCVSQSRADLTRTLEAFQQAGVRDILAIRGDMPGGPQQPW
RQHPEGLGNATELVRFIKAHGDFCVGVAAFPNVHQPDNDPELDARLVVAKAEAGAQYAIT
QLFFEASRYAELVERVRARGCDIPIIPGIAPLTVITQIERFAALADCELPADFVAELRAA
EDPAEVRRIGLARAISLCRELIDHGAPGLQFFTQNRWQATSEVLEALDWPRSG
>A0A538KEW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRISELYATAEEPVFSFEFFPPKTEDGERNFWNALGELRALEPAFVSVTYGAGGSTKDKT
LEIVTRIREQYGIEAMAHFTCVSATVEQLREQLDAMRDAGIENVLALRGDPPAGQEEWRM
TPGGLEFSAQLVAMIQGGYPEFAIGGACFPETHIHATSAEDDLRYLKEKVDAGARFLITQ
LFFDNALYDDFVRRAREIGIEVPIVPGILPITNVAQLQRITGLCGASVPPALLAELQARA
EDPDAVADFGVAYATLQCADLLAAGAPGIHFYTLNRSPATRAILSALKLTRPWARQEGLL
SVRG
>A0A4S2FNG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola sartorii|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYDTIDTLREFDPLYINITTHRSEYVYREL
GDGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEENGYAHALELEEQINAFNEGKFIDGTPIQAPLSPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVETGAGYVVTQMFYDNQKYIEFVERARKEGIHVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVMEAMKCKDDKEARALGIEWCVNQCRELIEYGVPGIHF
YTVGAVENVKEVARAVY
>A0A1H1L371|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. KT25b|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYLD
KGNGLLDKRITRMRPGTVGICASIMHKYKVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKDESYFKPTKGGNAFASDLVDQIANLNKGQYLHDDINVEHHSDFCIGVAGY
PEKHMEAPSLVSDLRRLKAKVDAGADYVVTQMFFDNNKYFEFVKAAKEIGINVPIIPGIK
PLAVKRHLQILPQVFKIDLPQDLIDAVYDCKDNKAVRQVGVEFAIQQSKELLAAGVPVLH
YYSMGKSDNIQAIASELF
>A0A537Z5I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDEILEERRPVFSFEFFPPKDKQGMTQLKGALAELAQDEPAYVSVT
>A0A537WVA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MLTHPRYEVFPVEGIADDVVAHVPTEIKVAVTSSPTRGIDATLRLCEELASAGFQVALHL
AARLVRDEEHLREILDRLGVIGVRDVFVIAGDVDLPAGKFDGATALLAAIADLGHQLDEV
GISGYPESHPFISDETTIQVMFDKEPFATYIVSQLCLDAGVIAWWIGAVRARGVRLPIHI
GIPGPVPSRRLLRIATRIGVGESTRFVRSHGGLLTRLFLRGRYGPGSLIERLTPLLGSPG
NGIAGFHVYTFNELATTESWRREALRRLETVQAAELGRRT
>A0A662DSC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARITACMEAKRTLSFEFFPPKTSAAQLTLGRTVGALEALEPDFVSITYGAGGSDRHRTG
DVVNWMRKETDLEPMAHLTCMGHTRTDVAGLLVEYRRIGVENILALGGDPPLDGDIPAGD
YRYASDLLADVAASGSFCVGVAAHPEV
>A0A0R2CHR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus cacaonum DSM 21116|TrEMBL
MAIFNYSFEISQNHLDVNLKNLNPEFISVAYTNHSLSFFKTTLSTAILQKNKTNVRTVIH
VPASAFSSAELNKLMITIKQSNLDSMLILSGEKKSQISQFSSSLKLTLFMHKKFPNLNIL
CACHPEAIISEKSLAQELLLMKKKELAGCSLFISQIFFDSALFKKFVLRCRAFGIKSRIK
AGIMPITTFNQVSFIKNTLQLHLPAEFSFATEASQLRTVGINFAINQINGLMLQKITDFH
FFATEDYNVVESILKGVS
>A0A538FBV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVRIGELLAAGRTLSFEFFPPGTEEAERTLEKTLIELEPLAPSFVSVTYGAGGSTRDKTR
QIVVHIARDTSMTPMPHLTCVGQSRSEVVEIVRRYRELGLVNILALAGDPPKGEGEGPSD
FRYAMELIELVRSLGDFSVGVAAHPELHPRSPDRESDRRHLAAKLREADFAITQFFFKAE
VYLAMLDELAALRVDKPVIPGVIPVTNVNQVERFARLAGAEFPPDLAQRLYQVGDRPEEV
RRIGVEVATGLTAELLDAGAPGVHFYTLNSSRATREIAANLGLGPPGRSPNGR
>D7A2F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Starkeya novella (strain ATCC 8093 / DSM 506 / JCM 20403 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIMB 10456)|TrEMBL
MSSDVERRSRRAGGRPVSVSFEFFPPKTAEMEATLWSSITRLAPLAPKFVSVTYGAGGST
RERTHATVERIVKETRLAPAAHLTCVSASKGEVDEVVRGYWDAGVRHIVALRGDPPGGVG
HLYEPHPEGYKTSADLVAGIRRTANFEVSVSAYPEKHPESPSFDTDLDILAAKVDAGATR
AITQCFFDNDLYFAYLDKVRARGIDVPVVPGILPVSNFKQAKNFSEKTGTYMPDWLAGRF
EGLDNDPETRKLIAAAVAAEQVFDLVDRGVTEFHFYTLNRADLVYAICHLLGIRPPLEAG
QSNGQAAA
>A0A502XRV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-6-5|TrEMBL
MIGRQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A0N0SSH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. H036|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMADWVAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVEKAGCDTPIIPEVMPVVGIKQLDRLPQLSTAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A1D8T569|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. WMMA185|TrEMBL
MGNPGSIYAERVTFDSVRGRASEGWVTHTPCIVDRIRSCKDGRVPFSVEFSPPRDEAAEA
RLWRAVREFERLGPAFVSMTYGAGGSTRDRTVRITGQLAEETTLLPVAHLTAVSHSVAEL
RSMVGAYADRGISNILVLRGDPPGNPLGEWQKHPEGVEYAEELVRLVLDLGDFHVGVASF
PEGHYRAPDLAHDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGEKPIIP
EIMPITSLRSVRRMLELSGSRLPAELEKRLDRAAGDGPEENRAAVREIGIDLATEMSERL
IAEGAPGLHFITLNFARATSEVLARLGDKVGSGVASHPVS
>A0A0V8JI67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia veravalensis|TrEMBL
MGLLEDLQSRILIGDGATGTLLYSHGIDSCFEELNITKKEEIQRIHRAYVEAGADVIQTN
TYAANYQKLARYGLEDAVKDINISAVRIAKQAAKKDAYVVGTLGGIRSFQKNAISTEEVK
RSIREQLFWLLNEGVDGLLFETYYDFEELKTVLSLARKETSKPIITHVSLHDIGVLQNGT
SLYDAFQELESLGADVVGLNCRLGPSHMIQSLEEVPLLDRAFLSAYPNASLPAYVEGKVE
YATNQEYFVESAKAFRNQGVRLVGGCCGTTPAHVQAMSQALKHEKPITQKKVKIRPVVEI
KEQEQTKEPHLHDLVKERRSIIVELDPPKQLGPTKFLDGAKALHKAGVDAVTLADNSLAS
PRVSNLAMASLMQQQTDARPLVHITCRDRNLIGLQSHLMGLHTLGINQVLAITGDPSKIG
DFPGATSVYDVSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVVRL
EKKISYGAHYFITQPLYSTKQIEEVYEATKHLEAPIYIGIMPLTSARNARFIHHEVPGIK
LSEDILARMDATGEDRIKGEVEGLAIAKDLIDTAYELFNGIYLITPFLRYEMTEILTRYI
NDKQLVTTERKN
>A0A6S6TST7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Sulfurovum sp|TrEMBL
MRRIKKGMLKKLNYGARGIITQPVYDLENAKELLEIFEECKHESVRDTAKNAALILGQFP
VVRARTANFISDKVPGITVPKIIIEEMDLAAMDGEDKEQEIGFNISKEIFDDILKVHPKM
HLMTHNRFDLCSDLIGDNNLDTIK
>A0A8I1RDK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
STGMACPMNCPKQLRNGPCGGVRSDGGCEVEPAMRCVWLEAIDGARAMAGGDAARLEAGM
PALAPLDHRRRGRSAWLAVVTGEGGAAAIAAEVDPAEAIAAEASPAEAGPGGARCESARG
EPQAAQPGSAVRDAQGEIGPFEAACRAGRFVVTVEVAPPDSADPAALVARAARFEGLVDA
INITDGAGGNCHMSSVAASAILAAHGLTPVYQIACRDRNRIAIQGDLLGAAALGVRNILC
LTGDDVSQGDHPEAKAVFDLDAVSLLRVARGMCERGQYASGRKLERAPRLFIGATANPFV
PPYAERVLNLRKKIDAGARFIQTQFCFDVRLLEDFMREVRAQGLHRRASILVGVGTLGSA
KALRWMARHVPGIHVPEALLARIARAGDQKAEAARACVETIREIAGIEGVAGVHVMGHRN
EDVLAGIIVESGLRQRAGLRTA
>A0A7W2HDQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces himalayensis subsp. aureolus|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFWAPKTPKGERNLWNALRRIEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADSTLTPVAHLTAVSHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWIPHPQGLTYAAELVRLIKESGDFCVGVAAFPETHPRSSDEDTDVQHFID
KCRAGADYAITQMFFQPESYLRLRDRVEAAGCTTPIIPEVMPVTSVKQLERLPKLSNAAI
PDSLKERILTAKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHPQA
>A0A6H3TWZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAITLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
SGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPIETRGTSSWKNWYLATEA
>A0A852UFK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. JAI121|TrEMBL
MGLLEELQSKILIADGAMGTLLYSYGIEYCNEELNLQRPEIVEKIHLDYITAGADIIQTN
TYGANTFKLERYGLENHVKEINEAAIQIAKRAAAPGGQFVLGTIGGIRGIRKSDATIEEI
IRMVDQQANHLLTGNPDGLLLETYYDFEELSSTVRHLRTLTDTPIIAQVSMHDPGILQNG
FALNDAFHQLEELGADIVGVNCRLGPYHTIQAFEQVTLPEKAFLSAFPNASLMDVEDGRI
VYASEADYFGRAALHLREEGVRLIGGCCGTTPKHIEAAKKHIGKLAPIAKKTVTPRKPIV
IREAEPSKTKPLHEKAKTERTIIVELDTPRHLDIDGFLQGAQVLHDAGIDSLTMADNSLA
SPRISNLAMGSMLKLEHTIQPLVHLTCRDRNLIGLQSHLMGLDALGLHEVLAITGDPTKI
GDFPGATSVYDVSSMELIQLIKQLNEGISFSGKPLRKKANFSVAAAFNPNVRVLERAVKR
LEKKIEAGADYFISQPVFTKEKIQEIYEETKHLSTPIFIGIMPLTSIRSSEFLHNEVPGI
KLSDDALARMRACGGDKDRATAEGIQIAKELIDTAAELFNGIYIITPFLRYDSSLELIQY
IKEIDAQKVRDHSYV
>A0A852UNH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. JAI121|TrEMBL
MSNLLNTMRERILVADGAMGTLLYSHGVDLCFEELNLTHPSQVLHIHQAYIEAGADIIQT
NTYGANYIKLARYGLEDSVKKINTAAVQIAKKAAGKDTFILGTIGGIHGSRTTNGTKEEI
KRSFREQLYCLLLEGVDGLLLETYYDFDELTTVLKIAREETDIPIVTNVSMHEAGVLQNG
LGLADALQRLENLGADIVGVNCRLGPHHMLESLETVPLLKRALLAVYPNASYPGYKDGKL
FYENEPEYFEKYALNFRKEGVSLIGGCCGTTPEHIRALVKGLINREPIQEKHVRQIETET
EVTMPDSKGAQKPSLLETVKKRQSVIVELGTPKHLNTATFFEGAQALKDAGIDAITLADN
SLANPRICNASMASLVKQQIGLTPLVHIACRDRNLIGLQSHLMGLHTLGITELLAITGDP
TKIGDFPGATSVFDVTSFELIQLIKQFNEGISMSGKSLQQKTSFTVAAAFNPNVRHLDRA
VVRLEKKKESGADYFITQPIFSPEKIVEVYEATKHIEAPIYIGIMPLTSSQNAEFLHNEV
PGIKLTDQVRARMALSNGNRDQATREGLEISKELIDAALEHFHGIYLVTPFMRYDMTVNL
TEYINSKMSATAVKGVIQTENSVY
>A0A838JKV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MQSQRDFPRTFSFEFFPPKTAEGMEKLRAARKQLAQLKPEFFSVTFGAGGSTRDRTLETV
LEIQAEGNNAAPHLSCIGSTQENIRAILEQYQANGIKHIVALRGDLPSGEVSAGEFRYAN
ELVQFIRAETGGHFTIEAAAYPEYHPQARSAEENLRHFKLKVEAGVDSAITQYFYNADAY
FNFVDDCEALGITIPIVPGIMPINNFTQLARFSDACGAEIPRWLRLKLQSYGDDTASIKA
LGLDVVTELCDRLLAAGAPGLHFYTLNQAGPASTIWQRLGLNT
>A0A5C8S2C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. WL120|TrEMBL
MPNAIRHRASRDGYHPIRVSIEFFPPKTEEMEKILWSSIERLAPLGPKFVSVTYGAGGST
RERTHNTVARMVTETGLKPAAHLTCVDATRDEIDAVVQSYWDAGVRHIVALRGDPAEGVG
HAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFENEVYLRYVDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLEGDVETRRLVAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKV
MAAKAA
>A0A5M9I0Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mediterraneibacter catenae|TrEMBL
MKIIDRLNEDGIHISFEVFPPKTDEGFDKVISAVDEIATLNPAFISVTYGAGGGTSKNTA
RIASHIKDDLNVLSLAHLTCASSTKEEVRKVIGNLKELGIDNILALRGDIPPGMDFPDTD
RFRFAYELVEEIRKHGDFCIGAACYPEGHVENEHKSDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSASQMKKSQELSGTVFPRRFLAILDRFGSSPA
AMRQAGIAYATDQIIDLLANGVRNIHIYSMNKPDIAAAIMKNLSEIIKA
>A0A4U1FLY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monodon monoceros|TrEMBL
QPDSGAAPPPEPRRVCWRLLIGHAAATGARSESSATRGGLGSEFTLAEMDRPKPKVLPAG
HCCPSLGMRAWEAGSARFSVPPSISRSSAMVNEPRGHGGPSPRWEGSSSGSESSKDSSRC
PTPVLDPERHERLREKMRRRVESGDKWFSLEFFPPRTAEGAVNLISRFDRMGAGGPLFID
VTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITGHLHKAKRLGLKN
ILALRGDPIGDQWEEEDGGFNYAVDLVKHIRSEFGDYFDVCVAGYPKGHPDAESFEAGLK
HLKEKVAAGADFVITQLFFEADTFFRFVRACSEIGITCPILPGIFPIQGYRSLRQLVKLS
KLEVPQQVKDVIEPIKDNDAAIRNYGIEQALSLCRELLASGSVPGLHFYTLNREMATTEV
LKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNS
SSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFAHYLSGEPNQNGYKVTC
LPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGWGPGGGYVFQKAY
LEFFTSRETVEALLQVLKKYELRVNYHIVDVKGDNITNAPELQPNAVTWGIFPGREIIQP
TVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQHIHDNYFLVNLVDNEFPLDSCL
WQVVEDTFELLNGPPQSKRETEA
>A0A429MJ16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHLSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKVKAGADFIITQLGYDIEAL
KQAKSFLTKHNYSQQILACVMPLTLGRANFMVKHKVA
>A0A0B2XXI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLESAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIVGGAPSLHFYSMNQVEPTRQLVVDLGLN
>B8H9M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter chlorophenolicus (strain ATCC 700700 / DSM 12829 / CIP 107037 / JCM 12360 / KCTC 9906 / NCIMB 13794 / A6)|TrEMBL
MSPPSLIDPQPKLSDAAPVALSYELFPPRSPAAAETLWTTIRELETTEPDYVSVTYGASG
SNRNTAIELIDRLLLETTLRPLAHLTCVGNTPEQLAGIIGQLLDTGVRGILALRGDLPND
ASQPVNGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPARHPESPSEEHDVEVLL
AKQRSGADFAISQVFFHSSQYSDLLARARRAGVTIPIIPGVMPFTSLRRVKRLGELAGVE
PSAELIERLAAADTDIERVRVGVDATVDLANAALDAGAPGIHLYTFNEHQSALEVLDKLS
LPRHSRAGSRTAAARAELAS
>A0A5Z1RA01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKITSILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IQKQGKFEIYAACYPEKHNESRNFIEDIHHLKNKVNAGTDKLITQLFYNNEDFYTFKQNC
ALANINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAV
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEEIRA
>D4LTM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia obeum A2-162|TrEMBL
MATVKLTELMKERQLLSFELFPPKTDKGMENLPGTIEHLCEFKPEYISVTYGAGGGNVGT
NREVCQMVKKAGTVPVTHFTVIKNTKEGIKDQLETYLSEGVDHILALRGDFPRGENSTGG
DFNYATDLVKFIRKEFGDKFEIAVAGSPEGHIACRSLDADISVLKMKQDNGADYIMTQLC
WDMEQFARWQDKIRKAGVTMPIDVGIMPILDQAATINMALSRNGCVMDRELSRLISKYWI
FPNPFDKAPFDDALEQKKEDFKKAGIEYTIKQIDKYRALGVEGIHLYALNKWKDVSEIIK
ESGMRTLV
>A0A7W5DBC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. Sphag1AA|TrEMBL
MRLPLSFEFFPPKTPEGAAKLRNVRQQLYAMAPEFCSVTYGAGGSTHEGTFAAVREILGE
GVSAACHFSCIGATRETVRTQLAELKAMGVKRLVALRGDLPSGYGIGGEFLYASDLVAFI
RAETGRDFHIEVACYPEVHPQAKSPEADLQAFAAKVRAGADSAITQYFFSPEAYWRFVDE
ARALGIDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASIKAFGLDVV
AALCERLRDGGAPALHFYTMNQSVATLGVLERLGWSA
>A0A435AQ32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.11.2.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>G9MZ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypocrea virens (strain Gv29-8 / FGSC 10586)|TrEMBL
MHIKDLVSETEKTKAPSFSFEYFPPKTAQGVQNLYDRMDRMDSFGPKFIDITWGAGGNIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLDKVNDALQKAYKAGCTNILALRGDPPRDQES
WTAADGNFRYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGAGF
IVTQMFYDADNFIRWVGKVRERGITVPILPGIMPIATYASFLRRAKHMQCRVPPEWMTLL
EPVKNDDVAVREIGKTLVAELCRKLLANGIHHLHFYTMNLAQATRMVLDELNWTPSPENP
LKQALPWKQSKGFGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPTSLQDIANTFVKYLEKKIETLPWSESALAAEADPIKDDLVA
LNKRGLLTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLMPPYLLEEMISRLDDFP
NLTYYAVTKDGGLKSNAPSDAPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGIDW
AKCYDADSPSRALIEGIMNGWYLVNIVNNDFRENSTIFGFLEGLEVKDLAVPVAGTA
>U4VI56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella intermedia 229E|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDVKPAAHLTCVDATREEVDRVVREFASLGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKAEAAL
EMA
>A0A093JL30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Struthio camelus australis|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDK
WFSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFSRSETFLK
FMKDCQAIGITCPIVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A2S8FRX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastopirellula marina|TrEMBL
MLSDFYQPGQLPVSFELYPPKTDKGMQSLMLQVEQLIKFNPAYITCTYGAGGSTRGRTLD
IVESVKSSFAVPVAAHLTVVGSSVDDLRSFLTEAKERGVDYIVALRGDPPHGETSFTPNP
DGLRYANELVDLINSEFNNFGVLVAGYPETHREAISPQSDLDNLKRKVDAGAQVIVSQLF
FRNSDFYAWRERCDKAGINVPIVPGIFPVQSLAQISKIANLCGALVPAELSDKLNEKPDD
SKWQAQVGTEYAAQQVIDLVDNTVPGFHFYVLNQAEATGQILAQLKDHLDGKRNGDPVNS
R
>A0A377XHF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae|TrEMBL
MHPEAKSAQADLLNLKRKVEAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPV
SNFKQAKKFADMTNVRIPVWMSKMFEGLDNDAETRQLVGANIAMDMVKILSREGVKDFHF
YTLNRAEMSYAICHTLGVRPA
>A0A386E0E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neorhizobium sp. NCHU2750|TrEMBL
MNDKTKDQRFEISFEFFPPKSEEMEAQLWETVEQLSLFQPEFVTVTYGAGGSTKEPTLAA
VTKIIDGTKMPTAAHLTCVDASKDEVRAVIEEYRAAGVRRIVALRGDPSAGIGTAYTPHP
EGFNQTADLVRALADYGDFDISVSAYPEKHPESPDMSADIDVLKSKADAGATRALTQFFF
DNEIFARYMDAVAAAGITLPVIPGIMPIQNLTQLKRFSKRCGATVPGFLDARFEGLDEKP
EERAKVAAEVAAEQIEDLGRRGFSHIHLYTMNRSPLVSAVLDNIGYKPQATKAVAAA
>A0A2N3NEJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lomentospora prolificans|TrEMBL
MDKITDKIAALPPDAFYTSLEFFPPKTVMGFSNLRDRLDRMERALKPLFVNVTWGAGGST
AQKSLDLAEICQRELGLTTCLHLTCTNMSRRLLDKALEDAKALGIRNLLALRGDPPRPDE
YKALDDAGSDEVTDFAWAADLVRYIRATYGDYFCIGVASYPEGHADGSAPESQSLENDLP
YLVEKVQAGADFIITQLFFDVDIYDKFERTLREHPSGAFKTIPIIPGLMPIQSYQMVKRT
TKLSHASVPDSIMARLDAVKGDDEKVKSVGVDILSEIVEDVKKIKGRTPGPRGFHFYTLN
LEKAVSFILERTNLIPVSDSDDEKVAVAEADESIRGVIPVVRVNGINGLNDISSNGVARS
STRRLSTVGSDPRNRVIVSGAQASHPDYEATAGEAGIPAEPVNTRANTLAISEGEGVLGR
EATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSTTQAVELWGSPTSAKDISDIFLRHLQG
SLSAIPWSEEGLLPETSKIQSHLVNLNHKGWWTVASQPAVNGYRSSDPTFGWGPENGFVF
QKSFVEFFLPTADWTNLRSKLQEPAVRESICFYATNLNGDFESSDAAASPGGTLTPSTNA
VTWGVFPGKEIITPTIIEEVSFRAWSEEAFGIWAEWARVYGKGSESEKLLNHVRKDYWLV
NIIHHEFIDGEALWRLLDA
>A0A0R2F1G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schleiferilactobacillus similis DSM 23365 = JCM 2765|TrEMBL
MKVVNCFNERPVISFEIFPPRPNASEKALDRFYTSLETLASLKPAYISVTYGAGGGDNKS
GTLDLCHYIKEQYGIEAVPHIPGLNFTKAGVQQYLKELEADGLDNVLALRGDLPEDGHIP
GDFQYASDLVTEIKRDGDFNVLGACYPDVHPEAKDSVSDIRGLKCKVDAGVSQLITQLFF
ENEHYYQFLERCELASIDVPVQAGIMPVVNERQIRKMATMNGVALPPKFLKMMAHYQDNK
IAMRDAGIAYAVDQIVDLLSEGVDGVHLYTMDNPVVTKRICEAIATLI
>A0A2T4DJM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. B9-2|TrEMBL
MQSQKQFKRRFSFEFFPPKTDLGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGVSTAPHLSCVGGTRQDIGELLDLYKEHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQVEPSISIWKNLGISDREKIAF
>B8DJ94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio vulgaris (strain DSM 19637 / Miyazaki F)|TrEMBL
MKIRDRIAASTRPFYSLEFFPPKERENWPGFFATVERLKALDPLFASVTYGAGGSTQDNT
LEITSHLKNVMGLEPMAHLTCVGATRERIADYLRRLREVNVDNVLALRGDAPKGQDIDWD
TAEFRYAADLVRFTRNEQPEMGVGVAGYPAAHPESPSFASDLRHTADKVNAGADFIVTQL
FFDVREYFDFVERLRAMGVTVPVLPGILPIQSLESVRRILSLCGANIPGKLYLELDAANE
KGGAEAVKEAGIAFAQQQIRSLLDGGAPGIHLYTLNRADTCLRIAEAVGAA
>A0A6L5NT93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. XMDDZSB0408|TrEMBL
MAFHHAQHTQSLNQSLSELSDINVSFEFFPPSTPEMEKILWNSIRRLAPLDPKFVSVTYG
ANSGVRDRTHGVIERIQQETSLVAAPHLTLVDASDEELVDLAKQYWNSGIKNIVALRGDL
PDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDARNAQSDLINLKKKIDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDTEIVPGILPVTNFKQTKRFADMTNVAIPGWLNKQFEG
LDDDPATRQLVGANVAIDMVKVLAREGVKDFHFYTLNRAELTYAICHTLGVRPNTNG
>A0A3N5PWM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium|TrEMBL
NGTVGPQRMLSIIDALRVSTLPLVAIPDIGIPTIIDGNAVYNAEPSYVAASARRLVEHGA
SIIGADGGATIDHIRAIASAVSTVIVGSVAPTISGKDHVPADEYVTPQRTSFHEKLGGTL
VTTVELDIPRGLDMSSVIDGARYLKEHGIDAVNISDGARARLRMSPIAISRLVFDATGME
CITHLACRDRNMVGLQSEVLGAHALGVRNILAVTGDPTHIGDFPSATSVYDVDSIGLIRA
LGRMNHGMDLMGNPLGEPTGFCISCAVNPAAEDLDREIDRLASKVEQGAHVAFSQPIFDP
EVLERFLDRTRDIDVKFMLGIIPLRTVRHAEFLHFEVPGMTIPAWVRERMRASGTDTESA
TETGIDLAVEMFNAAHDRVDGVYLMPPFKKYDIAVRILDRVRSTGTSS
>A0A8B5ER20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. US53|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKPKAAIKIYEAVKHLLKEELHA
>A0A8J7E8N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nodosilinea sp. LEGE 07088|TrEMBL
MMNYFRQAVVKGDFLITAEIMPPKGANPDRMLTLAKLLKGRVHAVNVTDGSRSVLRMSSI
AASTLLLQQGIEPICQMTCRDRNIIALQSDLMGAQALGIRNILALTGDPVHAGDQKGARA
VFELESVRLLNLIEHLNAGTDASGNRLSDGHLDIFPGAAVDPQLKSWSSVQRRFERKLMA
GAQFFQSQMIVDFDRLEMFMSQLALDAGKPIIAGIFLLKSAQNADFINRHVPGVHIPDEI
IQRLASAVDPLRIGIEIVVEQIAMAKQYCQGIHLMAVRREELIPEILEQAGILPIEHMKN
CHKLSA
>A0A7L7VTI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. BIM B-2242|TrEMBL
MFPTRIEIIPSAGIVDLVQDLVPRTTTLTMTCLPHHGIERTVRASVELATHGYKVIPHLA
ARSLQSRAELTGILRDCDVAGIKEVFVIGGDRKNPAGPYESALPVLEDIAQYTGGMMRAG
VAGYPEGHPTVAALDLIDALQGKQHLATSVVTQMCFDAPKILDFAALLRREGVDLPVWAG
VAGSVPRTKLVALATKIGVGSSLKFLSRKGPLARKLLSGDRYSPDALVAALENQPGIAGI
HLYSFNNLDAVPNEAAASSTKALQPELIRGAARDI
>C3U0R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium fCS1|TrEMBL
MKVTDHIAQAKDTLVSFEILPPLKGKTINTIYNNLDPFMEFKPSFINVTYHRIETMFKKK
ADGTFEKVEVKKRPGTVAICAAIKNHYNVDTVPHLICGGFTKRDTEDALIDLSFLGIDNV
LVLRGDAAKNEANFEPEVGGHSYAVDLQKQVDNLRNGIYLEEDIKNGGKADFCIGTAGYP
EKHFEAPNLETDMLHLKEKVDAGADYIMTQMFFNNQKFFDFVKACRNMGIEVPIIPGLKP
ITNKKQLSILPKVFHVDIPADLSNAILKAKTDEDVEQIGTEWLIQQSKELKAFGVPVLHY
YTLGKQHVILDVVRAIR
>A0A061Q5Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. JCM 19052|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDASRDELINIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A2N0PX41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus irregularis|TrEMBL
MKVINKILKAHEEGRPSWSFEYFPPKTQQGVQNLYDRMERMYRLGPEFIDVTWNAGGTTS
QLTSEIVATAQSVYGLETIMHLTCTNMPKEKVDKALKDAKECGCQNILALRGDPPRGQEH
WEACENGFSHAIDLVRYNRQQYGDYFGIAVAGYCEGHVDNPDKDDDLYRLKEKVDAGADF
IITQVFYDVDIFLNWVKKCRAIGISCPIIPGILPIQNYSGFNRIITLSKTIVPQFVLEEL
EPIKDDDAAVKEYGIRLAVDMIRKMFADGIKCYHFYTMNLERSTRLILEALEFVPPIENV
KPLPWCPSLSAKRKKENVRPIFWRNRTKSYIARTEAWDEFPNGRWGDSRSPAFGELDGYG
VSLKHSKKGALELWGYPQKHSDIFDVFVQYCRGEVNSLPWSDQPLAEESNIIREQLAHIN
SLGYLTINSQPAVNGVRSDHKIFGWGPKNGYVYQKAYLEVFISPTQLDALIARIERDTNI
TYYAVNKQGDLKTNTQSDGPNAVTWGVFPGKEIIQPTIVEAVSFTAWKDEAFELWNEWTK
IYDTDSISAKLITDIADNWYLINIVHNDFHDSDGIFIIFEQISVTDYEADR
>A0A0B4CWC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leisingera sp. ANG-Vp|TrEMBL
MTTPKISFEFFPPQNLEASFRLWDTVQVLAPMDPRFVSVTYGAGGTTRTLTRDAVATLHK
SSGLNVAAHLTCVNASKAETLEIADQFAEAGVTEIVALRGDPPKGEGKFTPHPDGFANSV
ELIKGLKARGDFNIKVGAYPDRHPEAADQSADVEWLKRKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDGSKLTPGILPIENWKGARNFAKRCGTIIPDWVENAFDKALRDDREELLA
TAICTELCSDLMEGGVDKLHFYTLNRPELTRDVCFALGITPKVALSNVA
>A0A6C1KBD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthobacter autotrophicus|TrEMBL
MTTPALAPAPAPVRASREMDRPPVKVSFEFFPPKSPEMEKTLWSSIARLAPLSPDFVSVT
YGAGGSTRERTHATVERIAKETDLAPAAHLTCVAATRDEIDAVVRAYGEAGVKHIVALRG
DPVTGVGTAYEPHPGGYAYANDLVAGIKRLGDFEVSVSAYPEKHPESASIDADIDVLKAK
VDAGATRAITQFFFENDVYFRYLDKVRARGIDIPIVPGILPVTNFKQASSFATRTGASVP
AWLLRRFEGLDDDVETRKLIAAAVAAEQVTDLVDRGVTDIHFYTLNRADLVYAICHLLGL
RPKAASAVADAPKAVAI
>A0A2Z2P0G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulosicoccus antarcticus IMCC3135|TrEMBL
MSQLSLSYEFFPPRSEAQQRRFWCTLGCLQTLNPAYISMTWGALGSTSAASLEILEHLVK
DATVPVTAHLSCSGQTEAQMKPMIEKLEALGITRFLALRGDVPAEASGHDATLSHASHLV
SLLAQDPRRDISVAAYPEVHPESASAESDMKWLKHKLDAGAKRAITQFFFEADTFLRFRD
KAVATGITQTLVPGILPIHDIQKVADFSSRCGATVPDHLIERFGRATTEESRYSAAVEQC
VNLCQRLRQEGVNEFHLYTLNQSTLSSAVSTELMGKSVESIVAA
>D4FUX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis subsp. natto (strain BEST195)|TrEMBL
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLVPIKEKEVKTRAKEFIS
VHHERTEPGLDEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALIKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNEIKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMARAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>A0A6N8FRC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gloeocapsopsis dulcis AAB1 = 1H9|TrEMBL
MLNNLNGTSLNLLRTAIIRGDFLITAEVAPPKGSNPSHMVQMAQQLKDRVHAVNITDGSR
AVLRMSSLAASVILLQHEIEPICQIACRDRNRIGLQADLMGAYALGIRNILALTGDPVKA
GDHVDAKSVFDLESIRLLKLIHKMNSGIDCCDQPLSDGATDLFPGAAVDPQLASWSGLQS
RFERKLEAGAQFFQSQLITDFDRLEKFMDQIANGCGKPIMAGIFLLKSAKNAQFINRCVP
GVNIPQHIIDRLEQAKDPLQEGVKIAAEQVQIARELCQGIHMMAVKREDLIPQILDLAGV
APVKRPIMSMKT
>A0A7W0RVK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTKTRGALPSLSFEFFPPHSPEASLRLWRSVERLAPLGPRFVSVTFGAGGTTRDRTVAAI
ATIAERARLNVAGHLTCVGASRDATLEVARSYARLGVRRIVALRGDPPKGAARFTPHPDG
FASAAELVAALRSVADFEISVAAYPEKHPEAASLAADLDNLKRKIDAGAANAITQFCFET
EDFLRFRDACAAAGIAAPIIPGVLPVENFAKMANFARRCQAAVPDWMTKAFARAETEADA
YLLSVSIACEQCDTLAVEGAEHLHVYTLNNPDLTFDVCRALGYEAAPLAAAMGGRALA
>A0A3Q7TD28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vulpes vulpes|TrEMBL
MGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQITGYL
HKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKGHP
DAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQGY
HSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYT
LNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWD
EFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYLSGE
PNQQGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGP
SGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWG
IFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLV
DNEFPLDNCLWQVVEDTFELLKGPSPEREAEAL
>A0A730C630|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar 4,[5],12:b:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7Y6ZC68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTNAPNISFEFFPPKNIQACFSLFETVEAFQGMDPTFVSVTYGAGGTTRELTHDAVSLLH
KEYGWNVAAHLTCVNATKEETLAIAKSYKDAGVNEIVALRGDPPKGAGKFTPAEGGFANS
VELITALKETGDFKIRVGAYPDPHPEAADENADVSWLKQKFEAGADSAITQFFFEPENFF
RFRDRCDRAGITGQLIPGILPITGWKGIQRFAASCGTPIPISYEAAFEHSTDHHQLSIDL
CTKLCEKLLAEGIEDLHFYTLNRPTLTKAVCANLGVI
>A0A1R1CT95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL H8-0259|TrEMBL
MKPDLRSAWENNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYMEAGSVL
LESNTYSANYDKLSKFGLESKVAEINRAGIRIARTAAGETGYVVGAVGSIRAGKRANLSS
AELKRFFSQQIAALLEEQPDGIMLETFYDVEELHLALRTVRKLSGLPVICQLAVDDSART
LDGLTLPEAFRILEQDGADVIGFNCNTGPNGIKRALGTLQGRLVLPVSIYPNAGVADYVD
GQYRYGASPEYFGQMAPVFADMGSRIIGGCCGTTPRHIAEISAALKEYTVTPLPEPDEHR
MAERISVHEHLSEDEGQGGAEPTLVDLVKERHTVIVELDPPRDLDIAKFMRGAEALRRAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIRQLNDGVAFSGKPLKQKAKFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIARIAKATEHLDIPIFIGIMPLASGR
NAEYLHNEVPGIQLSPEVRSRMQGLEGEAGRAEGVLIAKELLDAATAHFNGIYLITPFMF
YDMSVQLLEYVWEKQGRRLSPLFR
>A0A257TJ30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetia bacterium 21-64-5|TrEMBL
MPLTDVYGPDKFGLSFELFPPKTEAGEAELFQHLTELMSFAPSYVTCTYGAGGSTRAKTL
DIVERVHRQFGCPVASHLTCVGATVDDLRAYLREANHRGVANIVALRGDPPKGEARFQAV
EGGFGYACDLVTLIHGEFPQFGIAVAGYPETHQEAISPEADLENLKRKVDAGADVVITQL
FYSNEDFFRFRDRCARLTIGVPIVPGILPVTNLAQIKRITSLCGAKLPEPFQAALEAHEG
NADEQFEIGVNFATRQVQELIDAGVPGIHFYVLNKSPATSRVLRAVTRPA
>A0A3D4DMZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MSSLKSAPRLSFEFFPPNDIAGAFRLSDTVRALAPLDPSFVSVTYGAGGTTRTLTHDAVT
TIGSRYGLNVAAHLTCVDASREETLAIAESYAAAGVTEIVALRGDPPKGQGGFCAHPQGF
KDTVELIEALAGMGKFNIRVGAYPDPHPEAAGPGADVDWLKRKIDAGATSAITQFFFEPE
TYFRFRDACEKAGIDAPIIPGILPIERWAGVKKFATRCGARVPGWIDEAFDKATRDGRED
LLSVALATELCADLIDGGVEDLHFYTMNKPALTQDIARALGVTPRVELRDVA
>A0A2D8CDK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneola sp|TrEMBL
MKVTEHIEKANGDTLFSFEVLPPLKGQNIRSLFDHMDPLMEFNPPFVDVTYHREEFVYKK
RDNGLLERKTVRKRPGTVGICAAIQNHYKVDAVPHIICGGFSREDTENALIDLNFLGIDN
VLLIQGDTRKPEREFKPEPDGHAYASDLIEQVVDLNNGIYIDEDLENAKPSDFCIGVAGY
PEKHYAAPNMQTDMKYLKLKQDKGGHYIVTQMFFDNQCYLDFVKQCREAGITLPIIPGLK
PITSQKQLTILPQLFHVDLPMELSKAVEECNSKEEVVQVGIEWTIQQSKELMEFGVPSLH
YYSMGKSASVYEVAKELF
>A0A430E1V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. ABOLG|TrEMBL
MTLSINQLEEARRALDAPLFANVAGDAEVSFEFFPPKTPAMEATLWKSMATLAPLAPRFV
SVTYGAGGSTRERTHNTVARIARETSIPAAAHLTCVEATREEIDAVAEQYWAAGVRHIVA
LRGDPPRVGERYAAHPGGYENAAALVEGLRRLHPFEISVACYPECHPDSGDAAIDLDNLK
RKMDAGATRAISQFFFSPDVFFRFRDAVAAAGIDAEIVPGIMPVSNFAAVQRMSKMCGTD
VPGWMEHLFAGLDDLPDARQLVSATLAAELCRKLYAGGVKQFHFYTLNRAELSFAICHLL
GLRARPEVARVAA
>A0A0Q5VEJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus sp. Leaf369|TrEMBL
MTFGPCGGVTDDGGCEVGHGPCAFLPVPTVQWPGAARPRTGPEPHLLALMRQRPVVVADL
PAVALDRDSLERAADRVVGHVDAVLLGDHGAARVQFSPTYRASLVQARGLPVWQGLNCRD
RNRVALEGELAGLADLGVGAVHCVTGDHTATGDRPDAQPVFDLDSTQLAAAARAAGVLVS
VGETPHGPPAERRPHRLVEKVRAGADVCFVNHAGSVEALRSFVERATDAGADVPFVACVA
VALDPGSADQLRRFTSLRLPAGHLAGIESARDPRRAGIAAAIALAESYLSVPGVRGVDLS
GVPTPGAELTTATALAEIGRALT
>A0A2J9E1M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. FDAARGOS_221|TrEMBL
MSKPQFSFEFFPAKTDEGVEKLCHTFDALNELAPSYFSVTYGAGGTTRERTLGIVGTLRS
RANTPIAPHISCIGDDKNEIAKLLDFYKSIGINRMVALRGDLPSGQVGMGELPFAVDLVR
FIREHSGDHFQIEVAAYPEMHPQAKSFDSDIQNLVNKFEAGANSAITQFFYNAESYLYLR
DALEKRGVDTDKHKLVAGIMPITNSSSLIRFADSCGADIPRFIRKQLADYGDDRKAIREF
GFEVVHRLCEVLIAEGVPALHFYSMNRIEPNKRLVESLGLTTQA
>A0A1B3Z607|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas panacis|TrEMBL
MTVLSPFDSRVLGAVASQTVIDAIAQFVRSASIEAMARDDVALVAGRGLLAPGTTVMIPS
IAGDAGDDCVAAARRLRGLGLEPVPHLAARRLVSVDTVELLYRRLRDEADVRSLFFVGGE
LPTPAGEFGSALELLARTRPARFGFTEIGFGAYPEPHPTISAAVMEHALETKIAVAEDAG
LRSFVVTQFAFAAQPIVDWLDRFRERFADREVLLGLAGPAGIRTLMRYARLCGIGASSRA
LMRNGASIGRLLVESAPDAVIRELVMTDAIGRFGPLRPHFFPFGGLERTARWASAVADGR
IILRSAHAGFGVED
>A0A845UZS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenzhouxiangella limi|TrEMBL
MEAPQLSFEFFPPRDDVQTARFRTARDRLLALHPDYVSVTFGAGGSTRSRTVDTVREIAE
ASGIPVAPHISCMSEDLDSLRQLLESYDRFGVKRLVVLRGDRPSGRYAGVFEHAADLVAD
IRQRWGSRFHLEVACYPEHHPESPSPAADLRHFRDKVAAGADGAITQYFFNAECYFRFVD
DARALGVDVPIVPGVMPITNYQGLARFSRTCGAEIPQWIDKRLQAWDAEGDRESLIEFGH
EVVCNLCRRLLDGGAPGLHFYTLNRAGPSLRLCSDLGLGNR
>A0A7T1M0J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia sp. 2.29|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRTEEMEQTLWKSIDRLKNLKPKFVSVTY
GANSGERDRTHSIIKDIKEKTGLIAAPHLTCIDATRDELREIARDYWNSGIRQIVALRGD
LPDNSRKPDMYAADLVELLKAEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPSWMSRMYE
GLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A847X7Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallicola sp|TrEMBL
MGTYYRTKSKLALPACEMGNIFDKDTVLSIHKEYLQSGCKGIKTNTFGANKRYLNCNDDT
LEQIINSGCDIAMEAVEGQDAYIFADIGPIVENAEDGILEEYKKIIDLFIAKGLKYFLFE
TFSRDLYLKELTEYIKSQVPDSYIITSFAINPDGFTRSGDRGITLLENMNALESVDATGL
NCIAGPFHLLEYIKSIKLPAKTMFISPNAGYPSVINNRTYYSNSPSYFGNTVADFMDYGF
TILGGCCGTTPEYISRLSTTVESRQTQEVRITSKKPSERLKSDVADNMILKKINSGEKII
CVEYDPPASIEISEYMKNVKKLKEGGADAITIADCPVGRARVDSSLMAYKVKNEIGIDPI
VHLTCRDRNLNATKALLLGLNVEDILNLIIVTGDPIPTAEKDEIKSVFNFNSALLTKYIN
ELNEDLFTNKMNVAGALNINSPNFSLELKRAMKKEAHGANMFFTQPCLSKQAVENIKIAK
NYLDGKIMGGIMPIVSHRNAVFMDEEISGITVDDYIIEEYKNLSKEEASKRAVSLSLEFM
EKIEDSIDGFYLITPFNRVDIIGEIIKKRKNRD
>A0A416GT51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OF03-18AA|TrEMBL
MNLREYLKETNLITDGAFGTYFAAKYQTQEIPELANLSDPEKVKKIHEEYLNAGANFIRT
NTFAANTETLQERFPEVEKNIRAAVEIARSAADGKNVWIAGDIGPIPVNGTEDAAAAADE
YYQIAKTFAETGVKVLDFETFADLDGILPAIKKIRAEYDMFIAVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGRSGDKFLLAIPNAGYPTLTRNKLQF
GNTPVYFAEKMKELQELGADILGGCCGTDPEFIREMSARDGILKKSAPEKEAESSGQSEH
VVRQGFLYDENGNRKEKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMANKVRQATGLNVMPHICCRDRNAIAMRSLFLGAAINDIYNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTEEDAARLRRIKDETGARILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKASRKEGEAVGIQLAKEVMKLVGDFADGYYFSFPFNRVYMLKDILEK
>A0A1G6I6M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melghirimyces thermohalophilus|TrEMBL
MTTQPDLRTALTHSLLVGDGAMSTYFYQQGIPVGMTVEELSLSQPEWVEEVHRHYRRAGA
EVLETNTYGANRERLARYGLEGKVSRINREAALLARRAAEEAAYVVGTVGSISAGRVPNW
SQAEYRDLYEEQATALLYAGVDGIILETFLDLEELVLALEAIRPLTDLPILCHVAMIEVG
RMRDGHRLTEAFAELKRKGADGVGLNCRLGPLELQRALEKTVVPPGLLLSAFPNAGRLGL
TEGAYQYKSTPKYFGERALALRQQGVGLIGGCCGTTPEHIREVSKALQGLAPVPRVNPDP
GEEKEEVRPRVDVRTRPTVVEKVRRETTVIVEFDSPKDLDVTDYITGAKALHQAGVDAIT
LADNSMATTRMSNMALGSIIKERVGVEPLVHITCRDRNLIGQQSHLMGLDALGIDQILVV
TGDPTRIGDLPGASSIYDVNSFDLIRMVKQLNDGISFSGKPLKQRARFTVGAAFNPNVSR
MEVAIRRLEKKVAAGADFIMTQPVYDGEGMEKVYEATRDLSIPVFIGVMPLTSHRNALFL
HNELPGVKIPDAVMSRMDGLTGSDGRRVGVELAQELLDEALRYFSGIYLITPFHYWEMTA
ELTRFIRKWQERSPSIAAGRSQ
>A0A7X0MLQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas endophytica|TrEMBL
MTFSVNQLEEARRALEAPLYADVGGDVEVSFEFSPPKTDKAEENLWQSIETLCPLNPRFL
SVTYGAGGSTRDRTHATVARIARETKVPAAAHLTCVEATRAEIDAVAQEYWAAGVRHIVA
LRGDPPAGAADYAPHPGGYENAAALVEGLRRLHPFEISVAAYPEMHPNSADLAADLDNLK
RKLDAGANRAITQFFFEPETFFRYRDAAAAAGISAEIVPGIMPIGSFAGVTRMATMCNTD
VPGWLVRLFEGLDDHPAARQLVAATVAAELCRKLYAGGVKQLHFYTMNKAELSFAICHLL
GVRTRPAQERAAA
>A0A414PUE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM24-1|TrEMBL
MRVDEVFKQAASQGTTSVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A366D161|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinomonas aquiplantarum|TrEMBL
MKSELARKFQDASRGVYFIGTTPPKSSVQDEQLQEISTKLLNRLADIDVDGLIVYDIQDE
TSRIDKPRPFPFMETHDPRAWSKRLHLASDKPVVTYKSVSSRSAEAFSGWLTEAWEDYGI
RDLVLVGSPSSDGDIKLPLPEAYKTLAASEHDFNLGGVTIAERHAKKGDEHLRLIKKANA
GCDFFISQAVYDPQATADLISRYARTCKEEGNTPKRIILTFTPCGSAKTLEFMEWLGISV
PEATKHRILDSEIPLDESIKICRNALEQIIEVALPLGVPLGLNIESLTNRKEEIDASIQL
YRLLKATLDLKLAEQGLK
>A0A0G2IA54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emmonsia crescens UAMH 3008|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFVDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCEDQDDPKLLMQHLKEKVDAGGTF
IITQMFYDVDNFLAWVKKCRENGIVVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEAL
EPVKNDDAAVRNLGKSLVANMCKKMLAAGIHHLHFYTMNLQQATKMVLDELGLVPSHETP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSLKELSEIFVRFLDGNLDRLPWSEGAVTEETEIIKPDLLE
LNQKGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNP
DLTYYCVNKNGELKTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHPATSPSRRLIQQVMDSWYLVNIVNNDFHKTHDIFNLFKDLRVKDFDTEVEPIALAAK
PVDNTQQNGQPQKYINGSSTEATESEQKLNSN
>A0A374AEP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. AF14-19|TrEMBL
MNVVEIINEAIASGRTRFAFELLPPLKGDGMQKIFAAVEPLMALDPAYVNITFHREGIKE
TEREDGSVEWHVVRRRPGTVGISAAIQNRYGVEVVPHLICGGLSKYDIEDTLIDMDFLGL
HNVLALRGDKSQNEKRFMPHPQGHAHAVDLVRQIADMNRGKFIDGEVEECHHSKFSIGVA
GYPEVHAEARDITSDIARLRDKVDAGAEYVITQMFFDNAKYFDFVRRCREAGITVPIIPG
IKPLSTLRHLEILPETFGVKLPEELVREVKAHPDGVREVGTEWAIAQSRELMAAGVPVLH
YYTMSRTTNIQKIVKAVF
>A0A2N0AJJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira harrisiae|TrEMBL
MHISQVLGKKQTTISFEFFPPKNAEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEETGLTIVSHLTCVGSTKDEIREILKRYQKSGIHNIMTLRGDPPKGQKEFHKT
ENGFEFAGELVGFIKKEFPEMGIGVAGFPEGHPSTPNRLKEIEYLKWKVDQGVDYICTQM
FFNNNYFYDFVERCEIAGIKVPIIAGIMPVTSRKGMARMAELSLGTNFPAKLLNSLSRAE
DDEYAENVGIHWATEQVRDLLDHKVAGIHMYTLNKSKATRKIYESLGVRNFDSIG
>A0A0Q0XQL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium daejeonense|TrEMBL
MKVTQHLEAAKGKPLFSFEIVPPQKGSNIKDLYANIDPLMEFKPPFIDVTTSREEYVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGVDAIPHVLCGGFTREETEYLLVDCHYLGIENL
VALRGDPMKGEKYFEPTVGGNAYAVDLVKQIKAMNNGKFLHGELPLENAPDFCVGVAGYP
EKHIEAPSLEADLKRLKEKVDAGADYIVTQMFFDNQRYFKFVEAARAIGINVPIIPGIKP
VSVKRHLQLLPQVFWLDMPQELISDIENAKDNAAVRQIGIDFAVQQSKELIEFGAPCVHY
YSMGKSDNIQKIASQVF
>A0A2T0KJS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes italicus|TrEMBL
MSLGLPSRLPGTPSVGDLIRDPAPSFSFEFFPPKTPAGEQALWQAIRELESLRPSFVSIT
YGAGGTTRDTTVAVTERVATETTLLPMAHLTAVDHSVAELRNVIGRLAGAGISNILAVRG
DPPGDPTGEWVRHPEGVLYAEELVRLIRESGDFSVGVAAFPYKHPRSADVESDTRDFVRK
CRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILPGVMPVTRMATIERATQLSGAPFP
PALLTRFESVAGDEAAVRALGIETCAEMCARLLAEGVPGIHFITLNRSTATREVWQHLAP
AEIAAPA
>A0A8D9N3B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa PA38182|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A7C4A0J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division NC10 bacterium|TrEMBL
MENQFRKAMLDERAFVVTCELIPGLGSREKSQEKVLEFAQKACKGGKVHALSICDNAGGN
PSLEPDPLAAEIQKMGQVPLVHFTCKDRNRAQMLGTLYSYDRLGLENLLVMSGDYPVDTL
RGKAKPVFDLDPIHVLQLTADMNKGLEWQGVTGTVHLQPTSFFKGAAVSPFKQLESELMA
QYLKLIKKVEVGADFIITQLGFDVRKFDELIRFMRLRGLKVPVIGNVYVLNLGAARLMNR
NELPGCVVPDSLVAEISEEAKEPDKGRGKRLLRAAKLVAVLRGLGYKGVHLGGVVLPYED
VEFILEKAEEMSADWPAWVKDLQFSQKDAFYYFEPDPKTGLNTDIPVDRTRNLPRRSWGY
AVFRWVHDVAFDEKGILYRPARAFHRAIAGSLLEKPYAKLEHLAKVITNDCKMCGDCTLP
EHAYLCPQSQCAKYLLNGPCGGSYEGWCEVHYRKRKCIYVRAYDRLKAYGEQDQLLMGIL
PPRDWSLNETSSWVNYYLGRDHAGKSSSSAWAGTAAK
>W2RBR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora parasitica (strain INRA-310)|TrEMBL
MKVIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMAEADIKKALDEAKDAGIQNILALRGDPVRGASS
FDECDRGFSHAVDLVRYIREKYGNHFCIGVAGYPEGHVEIKDKKADIQYLKEKVDAGADF
VITQLFYDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTSFCNTFVPDEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRASESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSNTSTPRERRAMWGEAPAAKEDVRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGALSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
PSIQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEPGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSPATSP
>A0A2H0BC53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium CG23_combo_of_CG06-09_8_20_14_all_32_9|TrEMBL
DLAYLKDKIDAGAEYIVTQMFFDNKKFFNFVKDCHNAGIHVPIVPGIKPVSILSHINVLP
KTFYIEIPEVLEQEAKKCKTNDEIRQVGIEWAIMQSKELIAAGVPVIHYYTMGKSDNIRK
IADAVF
>A0A1V2CB99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Flexibacter] sp. ATCC 35103|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
VMALRGDAMKDEQYFMPKVGGNDYAIDLVKQISLLNQGKYLHEVMDADNRANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFKFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDSCKNNAEIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASHLF
>A0A074VLA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium melanogenum CBS 110374|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPRSKIDEALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDDPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGITVPIVPGIMPISTHAAFLRRANWSNIHVPPSWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLLDNGIMHLHFYTMNLAQSTRMILEELSITPSQETP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKNFRDVANLFAGYMQGKVESLPWSESPITDEADALRKDLID
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGLDW
SRCYDATSPSRYVINDLMQNWYLVNIVNNDFREQRGIFPLFENLEVPEMDKDMPVPEVPQ
QVNGTANGDKHDEEKKEEPKVGNGDVTDTKIPDSVHKKLETEINGADEKPATEPKDAPAH
NTGAGPSTSV
>A0A2H1XL47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Manilae|TrEMBL
MKKVSEIYGSAKEPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A1H0X9J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. OK268|TrEMBL
MKITEHIANANGKTLFSFELIPPLKGQSIQGIYNAIDPLMEFKPPFIDVTSLREDYIYKQ
HPNGLLEKLSYRKRPGTIAICAAIMNRYKVDTVPHLLCGGFTRDETENALIELEFLGIEN
VLVLRGDARNSDSSFVPTPNGHAYATDLLQQVVNMNNGVYLHEDYDNIAKTNFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGASFIVTQMFFDNQKYFDFVNNCRANGIHVPIIPGLK
PITTSKQLVNLSKTFHIDMPEDLCDAIHACKSEKDVKDMGIEWMINQCKELVKFGVPVLH
FYTMSNAGPTKRIAEAIF
>A0A3P3EQ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax beijingensis|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPEFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFLYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
TRKLGLDVPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLQGGGAPALHFYTMNQSVATLAVLERLG
>A0A6H0ZM02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium pusense|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNAEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLATAAHLTCVDASRDEVHQVVDEFRNAGVRHFVALRGDPSTGIGTAYQ
PHPQGYENAAALVKGLKELGDFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPAFLDERFEGYD
EDLEGRARVAAEVAAEQIADLQRRGVSEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A1H0PNR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas jinjuensis|TrEMBL
MTTPERRYSFEFFPAKTEAGHEKLLATARQLAAYKPDFFSCTYGAGGSTRDRTVSTVLQL
DGEVKVSTAPHLSCVGDSREELRTLLAQYKEAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRSETGDQFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGADSAITQYFFNADSYF
YFVERAEKLGVSIPVVPGIMPITNYTKLARFSDACGAEIPRWVRKQLEAYGDDTRSIQAF
GEQVVTEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3N1HMA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudokineococcus lusitanus|TrEMBL
MEGGPALRDVLADLRAAGRPSLSFEISPPRDEDAARLLWDSLRRVEALEPAFVSVTYGAG
GSTRDRTVRVAGEVAATTTVPPVAHLTCVSASRAEVRQVVGELVDAGVRSVLALRGDPPG
GPGSPWQQHPDGLGTALELVEMLRGMGDLTVGVAAFPNGHPESADADADARVLALKARAG
ASFAVTQLFFEAARWTELVDRAAGHGCDMPVLPGLMSITSLRQVERFERLSGAPVPAALV
ARLEDAHRTGGDEAVRRAGVEHTVGLGGELLAAGAPGLHLYTLNRSRAALEVADALGLGA
AVPAAS
>A0A542W376|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymomonas mobilis|TrEMBL
MDRILKENPDFATVPFLGDKEPHISFEFFPPKNEESDKLLWQSVERLAPLKPRFMSVTYG
AGGSTRERTRATVTRIARETTIPAVAHLTCVNASRDEIDDIARDYWNAGIRHIVALRGDP
PGGERFQAHPDGYANAIELVEGLKRIADFEISVACYPETHPQALSPEADIDFLKRKFDAG
ATRAISQFFLSPEAFLRFRDRVVAAGITAEILPGIMPTSNISGLKRMALSCGIAIPEKLD
HLMASLDQDEPSVKQMVSMAVVSDLCSQLAKEGVESFHFYTMNRAKITSALCRLLGRQPA
L
>A0A6N3UVM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLMNTARHLATFNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVHVPAAPHLSCVGDSKSDLRGLLEQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDISNFVRKAHAGADSAITQYFFNADSYFR
FVERVQAAGVTLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVHSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A833RJ70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carex littledalei|TrEMBL
MHIINKIKESTKSDDNHVIFSFEYFTPKFPKSATAEARAEIADAFIAKVARMAAHGASFC
DITWRPTSADVTINLAGRMQTEIGVDTMMHLTCLGMTLDGINRAIDGAKSRGVSNILALG
GDPPVGAPALAAVEPAKVNGKGVPVCGLDLVEHIRLRHGDYFGLAVAGYPEAHPSKILEG
SDVATKEGYEEDLVYLKKKVDAGSHFIVTQLFYDMSFFFDFVDDCRRIGIQCPIVPGILP
IVSYRSFQTMTKTCRTKVPTEIRETVERLKSDEVALAAYGIQLATDMCAEILRRGIRELH
FYTMNREEPTLAVLRRLGLVKGGETVPRVLAVKEEGEEKKSVANGAKNLVPA
>A0A7K8PLP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cochlearius cochlearius|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A0L1M4P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia megaterium|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINVAGVKLAKQAAKDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLNEGVDGLLFETYYDFEELKTVLTLARKETDKPIITHVSLHDIGVLQDGR
PLADALKELEDLGADVVGLNCRLGPYHMIQSLEEVPLPDRAFLSAYPNASLPAYVEGKLE
YETNEDYFVESARLFREQGVRLIGGCCGTTPAHVSAMSSALKDLPPITSKVVKMRPAVTV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRIRGEVEGLAIAKNLIDTAYELFDGIYLITPFMRYEMTEILTRYI
HDKQLVTSERKI
>A0A6V8PJ38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hakubanella thermoalkaliphilus|TrEMBL
MYKYLKTPTPDKSVSKALDTQGGNITGGARRESALQAVRIETSVREVRRMRIRDVIAREE
TSLSFEFFPPRTQEDEERLLETVRRLEAFTPTFLSVTYGAGGGTLKNTRHVVERIKEETS
SIVMPHLTCIGQDREELKAILSDYAAIGVENVLALRGDSPREITGHVIRDRLCYAKDLVH
LAASFNAFSIGVAVYPEGHRESPSLEMDMVYTKEKIDVGADFAITQMFFDNRYFYQFLER
AERVGIGVPIIPGIMPITDIEKIKRFSQICGATLPTQLVERMERASSLAEASKIGIDFAI
IAMMGPSPVNYENIKHFLSKAM
>A0A355R0U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGIDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQVARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQASPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALETRIEYWQTQVQSLEQWAPA
WHASWQMPGLPAVTFHPPQAGWRLDESRVDASFKEKARYHLMHGMHALLFSRRNSLSKAF
GWAVRQPLWGTRVGAHMLHTLERSVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A2N3QJ06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum subsp. globosum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLDEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAF
IRERRPDMKVYGACYPEKHPQADTLDHDIDNLKRKVDAGVTHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDRWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWANVQDLFA
>A0A2D0B141|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. R635|TrEMBL
MALKNEARGRNFGISFEFFPPKSEEMEGQLWDTVAKLQDWEPDFVSVTYGAGGTTKAPTL
SAVTRFLSQTPLATASHLTCVGATKEETHHMIDTFRKVGVKHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSIADFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGISIPIVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGLDEFHLYTMNRAPLVSAVLDNLGFSRRSPKSAGAAA
>A0A0Q9LPI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycicoccus sp. Soil748|TrEMBL
MALGQPSRLARPAQLTRSIPGMLAGPEPSISFEFFPPKDDASEALLWDAIRRLESARPDF
VSVTYGAGGSNQDRTVRVTERIARETTLTPLAHLTCVGASVAALRQVVGLYAASGVRNIL
ALRGDPPGNPGGEWVAHPEGLNHATDLVALVKSLGDFTIGVAAFPDVHPSSPGFDHDVEI
MVRKADAGASFAITQMVFDADSYLRLRDAVARRRPELPITPGLMPVTNFKQVARMSQLMG
TPLPEKVVARLQAVADDPAATRTVGVQVATELAERMLAEGAPGLHFITMNRSTATLEVHR
NLGLH
>A0A0N9VAQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter equi|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAINEFN
GKGIPVAPHLSCIGDDKVRIAELLDIYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDLDIKRFCEKANAGANAALTQFFFNPDAYFYFI
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDTASIKAFGHE
VIVKLCERLLAGGAPSLHFYTMNTTDPTRKLVLDLGLA
>A0A3C1H5X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKAITLFEKKPVLSFEVFPPKPNVPIDSIYQTLAALKDLHPDFISVTYGAGGSVPGASTA
EICETIQNQHGIPSIAHLPCINETKESVLEKLTVFREKGIENILALRGDRNPDVPPKTDF
RYAADLIAFIRQHGDFDIAAACYPEGHPEAPDLDTDILHLKEKVDAGATHLISQLFYYDP
DFYTFREKIAAAGISVPVEAGIMPVTSKKSIERMVSLCGASIPNRLAKLMARYADDPASL
KAAGLEYAITQILDLLENGADGIHIYTMNNPDVARYIMEQIRV
>A0A352TJR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MSSPNKTTFSFEIFPPKPTSEPSVIYGTLDALQDLKPDFISVTYGAGGGANCKNTVGIAS
YIQNTCQTESVAHLPCLYLSESDLNSILEQLRKNGIHNILALRGDRSETATPNGRFSHAN
ELISYIHNYDPSFHLMAACYPEGHPEQHSPTEELETLKRKVDAGASQFITQLFLDNDAFD
TYRNKVAQAGVSVPIEAGIMPVTNKKQIERMVKLCGATLPKKFLHILNKYEDNPEALRDA
GVAYAIEQIVDLIAQDVDGIHLYTMNRADVARDIDHAVHRLLQ
>A0A4R3PY32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sullae|TrEMBL
MALNTGDRRNIGISFEFFPPKSEEMEGQLWKTVAELQDWSPDFVSVTYGAGGTTKAPTLT
AVTRFLNETPLATASHLTCVGATKEETHQVIDHFRNVGVKHFVALRGDAPGGAGVPYQPH
PGGYANAAELVAGLRGIGDFEISVSAYPEKHPESRDVAADIDMLKRKADNGADRALTQFF
FDNDNFERYLEKVRAAGVKIPIVPGIMPIQNLTQLKRFASACGTVIPAFLDERFAGLDDK
VDERAKVAVDVAVQQIEDLVGRGLDEFHLYTMNRSPLVSAVLTNLGLRREGAKRAAGAAA
>A0A4Q5AFL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum subsp. globosum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLTEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAF
IRERRPDMKVYGACYPEKHPQADTLNHDIDNLKRKVDAGVTHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDRWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWANVQDLFA
>A0A1I8JPP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
MPENSSSALPRCRLKRSSSQEEQERPQPQPAASTARWPPASAAALREGPALVLLRVLPAA
HPGGRCEPRLQVRQLRQGPAAVLRRHLAPAGNPAGDSPTSSTSSPASLPLRQVASAMLNY
CGIDTVLHLTCVGQTEARLVRVLDRAKSPLGLKNILALRGDLPKTPTATQAAPQPRPAEA
RPSPATCFFCIGVAGYRGGPPGGRQLREDLRRLKEKVGGGFCAEHMAEWTPAAIHHHAAV
LRFGRLHPLRVRLPAVGIDCPIIPGVLPVQGYQSLRHIVKLSKLTVPDSSMLRCTQMCQE
LLQSGQVPRHSLLHAEPGRGDHPHFEKHRALREDLPRPLPWQPSANYERCAEAVRPVFWS
RRPTSYVHRTRHWDDYPTAASRSGSACGAASQQQRAGHLAGVRQPPVRETSQPGRCPSHP
AALGDEEPLPSSSESNEAAEARQRLAATTRCTAGGGSGGFVYQRAYLEFFLPGRRLPALQ
SALSSHGGGRVSFHIADRSGNVNLANFSEPIALTWGVFPASEVAQPTVCDGAAFLAWRDE
AFALWTEEWGRLYEEGSPSRRLIESVAETYLLVALVDNDFTEDSVLWDLTDQVARAADGS
DENLTHSNRTPETQLSYKRRSSRCSSFKPIKGAHKMIGSNVGVSPDYQERRSGRGHPVAI
TCADSPSRFVRQPVAEGGWPTSTAPLACSLKCSMAR
>A0A1Q5JG99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02261|TrEMBL
MNPDAPTFSFEFFPPKTDRGERTLWDAIRRVEALAPDFVSVTYGAGGSSRDRTIDVTKRI
AAETTLRPVAHLTAVGHSVGELRSIIGAYADAGVRDVLVLRGDPPGDPRGAWTPHPDGFT
YAYELVELVRSLGDFRIGVAAFPEGHPRSEDPADDLAHFVAKCRAGADYAITQMFFDPED
YLRLRDRVVAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAKDDPAGAY
RVGVGHATAMGLRLLDEGAPGLHYITLNRSTAALEIHRTILSARSVVHV
>A0A5N9HXH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MLENTDRFLTTVEIETSRGILMGEDSRKTMDSAQSLAEFDRVDFVSLTDNPGGNPHIRPE
VLGQELLSRGREVMINLSCKDYNRNSVESRLWALDSQGFSNVLALSGDYPVGGFEGQAQP
VFDIDSVGLIEMMAQMNEGLRNKTLGSSSSGHRLEETNFFTGCVVSPFKKLEGELMTQYF
KLALKVRTGAKFAVTQIGYDSRKASEIHNYVESNGINVPLIGSVFILTAPAGRFFNRWGV
PGVCVSDNLRDIANRQAKSKDRGRLFFSELAAKQIAILKGIGYRGVYISGRPSLDRVQKI
LELVDSYSQDDWREFAAEINFSQPGEFYYYEADENPGLSSTNINRDYISSRSKFARAKSR
IGVPLQYRIGKFVHDRVFSEGSSGFKLGRSIYKQIEKSKKLSDVAHVAEQVSKVPLYSCR
DCGDCSLPDIAYLCPESQCVKNQRNGPCGGTKAGQCEILDKECIWIRAYDRMKPYGDEVR
MLQGPVIFKDGALQNTSAWGNTFLGRDHHAKKSDAVDEP
>A0A1I7HIN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gallolyticus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADIIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAREAAGDDAFVLGTIGALRGLKQCDLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEAELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKETNFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDELADLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALEHFKGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A1H3HEY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter kyonggiensis|TrEMBL
MSQLSTCFTQNQFCVLVEYLCSMKEILPVKTQFAGFAALMTLADRVHADDDLAPIIAAQA
YPKHIEKVLHFAGKGRDIRDFEQFLNAAQAIGQQNLLLLTGDKLKNHHKGKDSSERTRYL
ESVNAVMAAKQHGDFCVGVAFNPFKYAEAERDAQYLKLHKKLKAGADYIISQLGYDLSAL
KEAKAFLTQHGYSQKLLACVMPLTLGRANFMVKHQVAGIVITPHMLKILGEEKESGLTDR
VYLRCALQILICKQLGFAGVHLSACHKPEEQLLLESYIEAYRHLGLDELELLWNTLWQVK
TGKEFYPALTYYSRPVSSMQILKYQHLHLMHDALFESKVAKGVGYFIFQSRFWNGSLAAQ
ALLKTEFVSKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVDQTQILKNNLILTVPIEVRGSSSWKNWYVNQAS
>A0A7L3D9J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pluvianellus socialis|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFEDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6I4UVL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceibacterium soli|TrEMBL
MNAYGSLHFEEAGEPLFADLPGDIAVSFEFFPPKSPGAESQLWAAVEKLAPCGPAFVSMT
YGAGGTTREGSLAAVRRLASETPLDVAAHLTCAGASKADVAGLAEEFWAAGVRHIVALRG
DGGPPGSRFTPHPQGYRSAAELVRGLREIAPFEISVAAYPETHPDAASAEADLDNLKRKL
DAGAVRALSQFFFSADTFLRFRDRAASAGIDAPIVPGILPVTNFGQTRKFAAACGAEVPG
WMAQLFLGLDDHPEPRQLVAATVAAELCRRLYAEGVRDFHFYTLNRAELTQAICHLLGRR
LPAQLEPVS
>A0A0R1J2S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus tucceti DSM 20183|TrEMBL
MAETNTGSTLSFEVFPPNSKVGIENLTKTLDQLKELKPSFISVTCSNHNVDYEKNTIDLA
KHVHNDLQVPAMVHMPAAYVNKKQVSRILNELEELNINQVLALRGDIIDGHAPENDFKYA
SDLTKFIKQEKPDFEVSGACYPEVHPESTNRIDDIKHLKEKVDAGCDQLITQLFYDNEQF
FRFQEECAIADINVPILAGIMPIINRKQALHILENCSAHLPKKFLAILDKYKDDPIALRD
AGLAYAIDQIVDLVTNDVAGIHIYTMNSAQTAKHIYDNTAAFFK
>A0A5N8Z2R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MTTVEIETSRGILMGEDSRKTMDSAQSLAEFDRVDFVSLTDNPGGNPHIRPEVLGSELLS
RGREVMINLSCKDYNRNSLESRLWALGSQGFSNVLALSGDYPVGGFEGQSQPVFDIDSVG
LIEMMAQMNEGLRNKTFGSSSPGQRLEETNFFAGCVVSPFKKLEGELMTQYFKLALKVRT
GAKFAVTQIGYDSRKASEIHNYVESNGINVPLIGSVFILTAPAGRFFNRWGVPGVFVSDK
LRDIANRQAQSKDRGRLFFSELAAKQIAILKGIGYRGVYISGRPSLDRVQKILELADSYS
QDDWREFAAEINFSQSGEFYYYGADENPGLSSININKDYISSRSKFAKAKSRIGVPLQYR
VGKFVHDRVFSEGSSGFKFGRAFYKQIEKNKKLSDVVHLAEQISKVPIYSCRDCGDCSLP
DIAYLCPESQCVKNQRNGPCGGTKAGQCEILDKECIWIRAYDRMKPYGDDVRMLQGPVIF
KDGALQNTSAWANTFLGRDHHAKKADAVDEP
>A0A6L3CAU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MQPSGSASQHLSAMLENTDRFLTTVEIETSRGILMGEDSRKTMDSAQSLAEFDRVDFVSL
TDNPGGNPHIRPEVLGQELLSRGREVMINLSCKDYNRNSVESRLWALDSQGFSNVLALSG
DYPVGGFEGQAQPVFDIDSVGLIEMMAQMNEGLRNKALGSSSSGHRLEETNFFTGCVVSP
FKKLEGELMTQYFKLALKLRTGAKFAVTQIGYDSRKASEIHNYVESNGINVPLIGSVFIL
TAPAGRFFNRWGVPGVFVSDKLRDIANRQAKSKDRGRLFFSELAAKQIAILKGIGYRGVY
ISGRPSLDRVQKIFELVDSYSQEDWREFAAEINFSQPGEFYYYEADENPGLSSININRDY
ISSTSKFARAKSRIGVPLQYRIGKFVHDRVFSEGSSGFKLGRSIYKQIEKSKKLSDVAHV
AEQVSKVPLYSCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTKAGQCEILDKECIWIR
AYDRMKPYGDEVRMLQGPVIFKDGALQNTSAWGNTFLGRDHHAKKSDAVDEP
>A0A641AES6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MTPKPVSDLAQRLENGLFAVTAEVTLPDSIEKNALVERAQMLEPYCDAINITDSTGAVPH
FSNIAAASILIENDIEPIIQFSCRDRNRIAVQADVIGAHAMGVRNIFCVTGDGVQTGDHP
EAKPVFDLDSVTLLTTINHLKTTGKFLSGRELDAKPNLYLGAAVNPFVPPFEERALRLLK
KHKAGASFFQTQYCFDIERFKSFLDRLLGLTKGAPPPLLVGVGPLRSARFARWLRENVPG
VAVPDHVIEKIEKYPRNEQQKAGVEACIEIVDAVKTLTGVAGIHVMAYNWEASVSEIVEA
TGLSKPERDK
>C5E412|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229)|TrEMBL
MRISEKLQNHRSKSTKPTFSFEYFVPKTTQGVQNLYDRMDRMYQSTLPQFIDVTWNAGGG
VLSQLTTDLVETSQSVLGLETCMHLTCTNMPVSQIDDALESARLSGCQNILALRGDPPVN
SDSWQPVEGGFQYAKDLVRYIRDKYGDYFDIGVAGYPEGHPETAGDDETLLDHLKEKVDA
GANFIITQMFYDADLFIKWCQRVRAKGVDVPLIPGIMPITTYAAFLRRANWCDVHIPQEY
FDRLDPIKDDDQLVREVGTDLIVSLCQKLLDSGYVSHLHIYTMNLEKAPQMILDRMELLP
SHDEPLDNHLAILPWRKSLNPQRRNEEVRPIFWQRRPYSYVARTSQWSVDEFPNGRFGDS
SSPAFGDLDLCGASLIRQSGKKSLELWSAPNSMEDIAQLVINYLRGELKYLPWSDTSLNH
EVDDILPELVTLNQKLIITINSQPQLNGVKSSHPVHGWGPRDGYVYQKMYLEFLLPKEKL
SKLHDCLVNDVMLTYFAVDHNGNLTTNHQDGTRANAVTWGIFPGREVLQPTIVEKVSFLA
WKQEFYHICEEWKLNFINHRCDQSVKLLQHLIDDYVLVNIVDNDFISPENRIFNLLSSI
>A0A1F9XAE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFCSPHIGHO2_02_FULL_61_10|TrEMBL
MKVTERLKTGAKVFSFEFYPPKTEADSVKLFEAARELKKLGPDFVSVTNSSSGTMPYRTV
ALSGVLKAELGLEVVAHLTCVAHTRAEIKEICLRLKGMGIKNILALRGDIHNIEGLPPRR
EYSYATQLTEDLVKTGDFAVGGACYPEKHPDAPTLEEDISHLKEKIAAGAEYLITQLFFD
NNFYFRFLEKTAAAGIKVPILPGLMPLTGYKQMQNFTQMMKVTVPEALRRGIERWEGDKE
GMFKFSVEYASAQAEELLKGGAPGLHLYTLNRSRAAIEILKNVKGETSQVRS
>A0A3D4XRE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium|TrEMBL
MSAPQLSFEFYPPKTPDGATNLLTVQKQLMPXFFSVTFGAGGSTRDKTLETVLKIKDQGV
NAAPHLSCVASTKDNIYAMLQEYRQSGIQKIVALRGDLPSGTLSAGEFRYANELVHFIRQ
ETGDYFDIHVAAYPEVHPQAANALEDFKNFQRKVDAGANAAITQYFYNVEAYFDFVNQCE
KAGITIPIAAGIMPISQYSQLFRFSEMCGADIPRWMRKRLESFGDDRASVQAFGVEVVTR
LCEQLIAGGVPNLHFYTMNQSALTLAILKNLHLAP
>A0A5N9BNC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MKITEGCFEATGHTSIICDFSPPRSGDSAVVTQAQIDADFILVAYNPGRAVRTNSAMLAA
AIQQSGKDAVFTLATRDMNKLAVQSLLLGAQLLGLQNVVVVQGDLFGEQDQARVATVNDY
HSTGLISAIVQMNQGQDFKEAELRAPSDFCIGGAVDLGRGIEEEAQLAVRKVQAGAEVLI
TQPIFNV
>A0A5N9AZQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MTNKDTNQNLNMISLRERLNVKNFVVTTEINPPKGPDTTTVLEKASMLKNYVDAINVTDS
AGANMAMAPITIAHYLTTLNINPILQITGRDRNRIAIQGELLAAHALGISNVLCMSGDSP
ADGDHPEAKGVFDLDATGILQSLEALRSGFDLSKSKLNAPADFLVGAVVNPGAKDIEKEI
TRMQQKIDLGAQFFQTQGIFDTNQFESFMEKITNFKTPILAGLILLKSAKMAQYLNDNLF
GVNVPDKIIQTMDASDNRIQTSIDISSSIIESMKPMCSGVHIMAIGWESHIPKILQNTNL
T
>A0A1C6T7D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora rhizosphaerae|TrEMBL
MALGLPSVLPNPQPAIGELIRECQPTFSFEFFPPKTPHGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVPHPEGVRYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTEHFVR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFERIADDPEAVRRLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWQHLR
ADARV
>W9BRW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomonas sp. CACIA14H2|TrEMBL
MTLSLKQLAEAREALGTPLFAGLAGDVEVSFEFFPPKTEKMEATLWDTLTTLAPLGPKFV
SVTYGAGGSTRERTHATVARIAAETAIPAAAHLTCVDASRDEIDAIAQSYWDAGVRHIVA
LRGDPPRMGEKFVAHPQGYANAADLVKGLKQVAPFEISVAAYPETHPDADCADSDIDNLK
RKLDAGADQAITQFFFSPEAFFRFRDAYTKAGITAPILPGILPVSNVATTRKIAGSCGTE
IPQWMNDLFEGLDDHPTTRQLVAATVAAEMCRRLYSGGVRHFHFYTLNRAELSFAICHLL
GLRAPKVAAAPVLQENAA
>A0A2J9QER0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mutans|TrEMBL
MSRLLDKLKTDILVADGAMGTLLYADGLESCHEYYNISHPERILAIHQAYIAAGADIIQT
NTYGAKRHRLKSFGHDKEVKAINQAAVHLARQAAGDNTFVLGTIGASHGLKHCELSLEDI
ISQTVEQARFLLETKQIDGLLLETYYDIEELEAALKALRPLTDLPIITNVALHEPGITEN
GRPLVEAFSNLVMLGADIVGLNCHLGPYHMIQSFKQVPLFAQSYLSAYPNASLLSFSSDD
NETPYHFSQNADYFEYCAKLFVEEGVRLIGGCCGTTPEHIKAIKRGIRGLKPIERKVTTP
LISQEDLIYEVEKKESLVDKVKKGITIIAEIDPPKTLAVDKFVDGVKALDEKGIAAITLA
DNSLARTRICNLSMASMLKDEIATPFLLHLSCRDHNMIGLQSRLLGMDLLGFDHILAITG
DPSKIGDFPGATSVYDATSFKLLSLIKQLNQGHGYSGASLKKATHFTVAAAFNPNVKNLS
RTGRLIEKKVAAGADYFITQPVFSETVIQELSEVTKPYEQPFFVGIMPITSYNNAVFLHN
EVPGISLSESFLAKLEAVKDDKETCQKVALAESKKLIDAVLAHFNGIYLITPFLRYDLTV
ELIDYIQVKTATVAKKRT
>A0A6L6X5B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces typhae|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNSLRRVEAVAPSFVSV
TYGAGGSTRAGTVRETQQIVADSTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLALR
GDPPGDPMADWVKHPEGLDYAAELVRLIKESGDFCVGVAAFPAMHPRSSDWETDVRHFVD
KCRAGADYAITQMFFHPEEYLRLRDRVEAAGCDTPIIPEIMPVTNVRQLERLPQLSNADF
PAALKERILSSKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHPQA
>A0A847QIU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonellaceae bacterium|TrEMBL
MTLTRISVELVPRNEEFLTAELNALIDQFPVDTVNIPDLLKFDIRSWTGSGLVRRAGKKA
IPHIRAIDIDVRKALPMAQFLIDNQIMEVLVLTGDRPQDMGHKIYPSTSVDVIRKFKQEL
PNVKVYAAIDQYRSSIRTEIDYAMRKLYAGADGFFTQPFYDLRFMEIYAEQLQDTEVFWG
ISPVVSENSVKYWEVKNNVVFPAGFKPTLEWNINFAKQALDFVNSINSNIYFMPIRIKVA
EYLSGIFNFIKEDKNV
>A0A150M0X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parageobacillus caldoxylosilyticus|TrEMBL
MGLLQDLKERILIADGAMGTLLYSHGVDRCFEELNLSKPEEIIHIHEAYIAAGAEVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLAKQAAGNKAYVLGTIGGLRSINKSAVSIEEVK
RTFREQLFVLLNEDVDGLLLETYYDLEELETVLAIARKETDKPIIAHVSLHEVGVLQDGT
PLAEALARLEQLGADVVGLNCRLGPYHMIRSLEEVPLPNRAFLSAYPNASLPDYRDGRLV
YETNTDYFKETALAFREQGVRLIGGCCGTTPKHIEAMANALTDRTPVQTKTVKQRHISVS
ISSNEPNAAPPLQDIVRERRSVIVELDPPKKLGIAKFLEGAKALKEANIDALTLADNSLA
TPRISNMALGSIVKQQLGIRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVER
LEKKIQCGAHYFITQPLYSERQIEEVYEATKHLETPIYIGIMPLVSARNADFLHHEVPGI
TLSEEIRSRMAACANNPVQAAREGIAIAKSLIDAAFDLFNGIYLITPFLRYEMTAELVRY
IHEKEKAAQERKVLHG
>A0A8E1WK07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter lissarensis|TrEMBL
MREQTNAQTVPDEAPRRLIDGAISIELSPDQVRDFRPSQAILPAGSRVFLTHLTGKPLGA
QIEAARTLIEMGYVPVPHLGAKNFESVKDYVRQIETHGRNGVTDALFVGGNPLTSSGPLR
EAAELLAHPILSSAGIRTAFIGGYPEGHPSISKDALRDATMRKLSLCHGKGLSPHIVSQF
AFDGRSMANWAKELQAEHPDLPVRLGLAGVTSLPKLIKFAVMCGIGPSLAALRRSGAGLF
NVLADKDPGDVIKGIEASYPSPFGPLDIHFFPFGGWQKTLDWIETARLT
>A0A1V9WAF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. CDB3|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKSHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKESAIEEGIRISQELIDTAMKYFNGVYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A3D4TJ50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MSAGMPLRADAFINTFSLEVSAKAMPALRAEASRIPRGTIISIPWLASEDDDARLAAART
VRELGFEPMPHLSARRIGSHAALERFLERAAGEAGVARCLLIAGDLATPAGPFADSMSII
ETDLLERHDIKVVAIGGHPEGHPVMSSDERWQVLQRKCRGIEARGMAPLVVTQFAFDADI
VLAWLDALRTRGIAAPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVKGLTCAHGQVSPHLFPFGGIAPSLEWLEQYRRRTSGTGG
>V6JU46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces roseochromogenus subsp. oscitans DS 12.976|TrEMBL
MRDILASGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVKE
TQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWVPHP
RGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFF
QPESYLRLRDRVAAAGCGTPVIPEVLPVTSVKMLERLPKLSNAVFPDALKERILTAKDDP
AAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>A0A495SJP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 123|TrEMBL
MKVTQHIENAKGETLFSFEIVPPQKGKNIQELYDNIDPLMEFKPPFIDVTTSREEYIYVD
KGNGLLNKQLTRMRPGTLGICASIKHKYQVDTVPHLICGGFTREETEYMLVDCNYLGINN
VMALRGDAMKDEQSFVPKEGGNKYAVDLVDQIYQLNQGKYLHELMDIDNKADFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNTKYFEFVAKAREIGITVPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLINAIDKCKTPADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A2S9EL86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas poae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYQQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLHNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A4R0R1R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. BS56D|TrEMBL
MTSALQRILAQGGGPALTAEVMPPRGGDPSHALAMAERLRDRVHAINVTDGSRAVMRMSS
LALCRLLLDAGHEPVLQIACRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAGDQSAAR
PVNELEAVRLLQQVSAFNRGEDPVEGALADGPTALFAGAAADPHSASWSGLARRLERKRM
AGAAFVQTQMVMDPEALERFCRELADPLELPVLAGVFLLKSARNAQFINRMVPGACIPES
LIERLAQAQDPAAEGVKIAAEQVHRYLGIAQGVHLMAVKAEQRIPEILECAGISSLPG
>A0A068DQK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Walczuchella monophlebidarum|TrEMBL
MKVTEYIERAKTTLLSFEILPPLIGRSILDIFDVLDPLMEFNPPFINVTYHREEYGIKKL
RKKKKFSRRPGTMAICAAIMNKYGVDPVPHILCGVFNKKRTENILIDLWLSGIRNIFVLR
GDTMNFEKKNVPEHNVHNHSVDLVKQIYYLNKGIYLDKNFIGVHTTDFCIGVTGYPEKHF
ESPNMNEDIFHIRKKITSGADYIITQMFFDNTKYFNFVSRCRSEGLTVPIIPGIKPISSK
SQLWNIPAHFYINLPHELVCEVQRAKNNKDVSRIGIEWAIQQSKELKKYGIPVIHYYTMS
NPHNVYEIVKNIC
>D2ACP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella flexneri serotype X (strain 2002017)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7C8VQR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orbilia oligospora|TrEMBL
MQEKITDKIKALPKDATYFSLEFFPPKTPAGLQNLHARLDRMAKGLRPLFVNVTWGAGGS
TATKSLELASLCQSHGLTTVLHLTCTNMSKSVLDDALENAKLMGIRNVLALRGDEPRQHE
YLDVTEQVRNGSGENEFVYAIDLVRYIRKQYGEYFAIGVAAYPEGYAETAYPVAQDTARD
LPYLREKTAAGADFIMTQFFYDVEAYISFEKVLRNDESGVFKDIPIIPGLMPVQSYQIFR
RTTKLCSVKVPGTISSRIESVKADDEMVKEHGIQVLTEMIGKIRSSTESDGGLPRGFHFY
TLNLEKAVAFIVERCNLIPEIPTSNEMAVEDEDDEGPGLLTVNGGGASIPRRSRRTSSII
SDPHNRVIVDTVSSARSELQAEAGEAGVPKILDPGSQEGNLAISEGEGSLGREATWDDFP
NGRWGDARSPAFGEIDGYGVSLHRTPTEALKLWGKPTSTKDISDLFVKNSKGELEAMPWS
EDILNPESFLITEELVKMNAKGWWTVASQPAVNSAKSDHPTFGWGPKNGFVFQKAFVEFF
ILDEEWTELKKKLENEGKEDVSFYAGNKAGDFQTNLASDSSLNAVTWGAFPGKEIITPTI
IEEVSFRAWRDEAFDIWSEWQRIYPLSSATSKLLGELKNKLWLVTIIHHDFVNADGLWKD
ILGL
>A0A8F8UQZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANLLKLTRYDLQDQVTTINQAAVKIAATAREHADHPVYILGTIGGLAGDTDATVQR
ATPATIAASVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFIGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A6G2YN59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8373|TrEMBL
MALGTPSTRTDHARTVREMLATGATSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVKATQDIAAESTLTPVAHLTAVDHSVAELRNMVGQFADAGIRNILALR
GDPPGDPMGPWVEHPQGVTYAADLVRLIKEAGDFCVGVAAFPERHPRSEDWDTDVRHFVD
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCDTPIIPEVMPVTNVRQLERLSQLSDAKL
PDDLKERILAAKDDPAAVRSIGIDFATRFSAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A8B8P0A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodamnia argentea|TrEMBL
MKVIDKIRESAGVCNGDASQRKAVFSFEFFPPKTEDGVDNLFERMDRMVVHNPSFCDITW
GAGGSTADLTLDIANRMQNMICVETMMHLTCTNMPVEKIDHALAAIKSNGIQNVLALRGD
PPHGQDKFVQVQGGFACALDLVKHIRAKYGDYFGITVAGYPEGHPDVIGKDGVATLQAYQ
SELAYLKRKVDAGADLIITQLFYDTDIFLKFVNDCRQVGIRCPIVPGIMPINNYKGFIRM
TGFCKTKIPAEITAALEPIKDNEEAVRNYGIHLGAEMCKKILANGIKTIHLYTLNMEKSA
LAILTNLGLIEEAKVSRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTMGWDQYPRGR
WGDSRSASYGTLTDYQFMRPRARDKKLHEEWVVPLNSVEDVHEKFKKFCLGKLRSSPWSE
LDGLQPETRIINEQLGRINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFF
CSPEKLNTLVEKCKGFPNLTYIGVNKEGDKWISNVGESDVNAVTWGVFPAKEIIQPTVVD
PASFSVWKDEAFEIWSRGWARLYPEGDPSQKLLHEIQSSYFLVSLVDNDYMKSDLFAVFD
DI
>A0A2U2N6B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spiribacter sp. E85|TrEMBL
MSAVAPMTQSLDAGYAALAAPRWELIPIRGMLEQAGLLPRGSAITVTCSPKHGIERTLES
AELLAGMGHLVVPHLAARLVQDRHHLQAILERLQAAGMDEVFVIGGDAPRPVGEFAGGHE
LLQAMAELEPRPARVGIPAYPEGHALIDAATLEQAMQAKAAFASYLVTQICFDPDQIIEW
LRDMAGRGPGLPVHVGLPGVMEPRRLLGLAMRIGIGNSAKVLRRSNGLFGHLLGGEYTPD
DLVWRLAPLFEDPTVRLVNFHLNTFNQIEPLQRWRHRMLEAMAPYCQPAEPDEEGGFSTD
YGQPDLA
>A0A418WXG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noviherbaspirillum cavernae|TrEMBL
MSQQHFSIEFFPPKTPEGVEKLRATRAKLAELHPHYFSVTFGAGGSTQKGTLETVLDIKR
EGHDAAPHLSCIGSSRDSLREILAEYKSHGIKRLVALRGDLPSGYGSAGFSAGEFRYANE
LVELIRAETGDWFHIEVAAYPEMHPQAKSPQDDMQSFVRKVKAGADAAITQYFYNADAYF
RFVDEARKAGTDVPIVAGIMPITNYSQLMRFSDMCGAEIPRWIRLKLASFGDDAESIKAF
GLDVVTSLCERLLVGGAPGLHFYTLNQAVATLEICRRLRAPAR
>A0A554VXL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. KBS0703|TrEMBL
MSTEAVARIRLEVFPSADLLTQLPAAFDITGSVSVTCLPHHGPARTVAASVNLASLGYHT
VPHLAARSITGEAELHSLLLQLQEAGVSELFLVAGDRRTPAGPYSWSGELLEAVNAYSPD
FSIGIAGYPEGHPQLSREQLSSSLLTKAPLASSVVTQMCFSAEAITRYLRSIREAGIELP
VWVGVPGPVSIRKLVSLGARLGVGRSLKLARGTGMAGALWRGDDFLSYDSGRLIREVHQE
LAGDPLFAGFHVYTFNDLGRMRGLLDDLRTLQPTAALAPGSTSIPLFPAKI
>M6V0P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira santarosai str. ZUN179|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSRLDPDFVTVTYGAGGSTRSK
TAQILSEISKNYSFPTVSHFTCVGANQEQILKTLKEIRSSGIVNLMALRGDPPKGEGQFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPNAKNLEEDVENLKRKVDAGADFLVS
QLFFVNSIFENFLNLVRTAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A2A2EE11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium criceti|TrEMBL
MPIFSLEIFPPKRTAPVGTIYDTLDGLQGLQPAFISVTYGTGKSVDRTATARIANTVRAE
YGIPAVAHLTAQYLDEEAAEEALDLFDQAKVSGILALRGDRNPEREPAHVFHYASDLAAF
IRERRPDMKIYGACYPEKHPQAASLDEDIDNLKRKVDAGVTHLISQLFYDDEDFLRFRDK
ARAAGIDVPIEAGIMPVVNGRSVRHMAGMCGSKIPERLNVMLDAWGQDPASLKEAGIIYA
SEQISDLVARGVDGIHLYTMNRPCVTRRIWANTKPFFA
>A0A3D5MHU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRNAVNVSFEFFPPKTDAAEANLWSAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIITETTLRPAAHLTCVEASRAEVDEVIEGYKAIGVDH
IVALRGDPPGSSGIGGAYTPRADGYANATELTAALSRIGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLKRMT
AACGAALPDWLAGHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAVA
>A0A2K3LCU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trifolium pratense|TrEMBL
MKVIDKIRSAAADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANKMQNIICVETMMHLTCTNMPVDKIDHALETIKSNGIQNVLALRGDPPHGQE
KFVQTEGGFACARDLVQHIRSKYGDYFGITIAGYPEAHPDVIGNDGLAPAEGYQKDLAYL
KSKWHA
>A0A7K1J385|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium canis|TrEMBL
MHSPLFSLEVFPPKRTSPVGTIYDTLDGLDDLKPDFISVTYGTGKSADRTATARIANTIR
SEYGIDAVAHLTAQYLTASDVDEALAMFDEAKVSGILALRGDRNGDREPAGVFHHASDLV
RYIREHRPQMKIYGACYPEKHPQSATLDDDIANLKIKVDAGVAHLISQLFYDNDDFMRFL
DKTRAAGIDVPIEAGIMPVTNAKSVRRMTNMCASRVPRKLARMLDKWGMIRRHCVKRASS
TRASRSATSYARESTASTSTR
>A0A6I1FHU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus aerolatus|TrEMBL
MKLLERLQHEVLTADGAMGTLLYSSGIDFCYEELNVENPEIIEKIHLEYIRAGADIIQTN
TYSANALKLARYGMENRVQELNKAAVRIAKKAAAPEQRFVLGTIGGIRGVGKSIASLSDI
EAAVRQQAEAILSEDPDGLLFETYYDFEELTTVLTLIRQLTDLPIITQVSMHEPGILQNG
QPLNRALGQLESLGADIVGVNCRLGPYHTIQAFEEVTLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGQAAVHLRNEGVRLIGGCCGTTPKHIKAAKKALAGLPPITEKRVKAKKPIM
IKESAPPSVPPLHEQVKKERTVIVELDTPKHLDTAAYIKGAKALQQTGMAAVTIADNSLA
SPRVSNLAMGSILKMKHQIRPLVHITCRDRNLIGLQSHLMGLHALGLHDVLAITGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGISFSGKPLKQKASFSVAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVFTKEKIIEVYEATKHLTTPIFLGIMPLTSSRNAEFLHHEVPGI
KLSEETLARMKAYEHDKAAAALEGVKIAKELIDIAAELFNGIYIITPFLRYEMSIELIRY
IEELDLKINERGITHVQTTLN
>A0A3M8T422|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces botrytidirepellens|TrEMBL
MAEVLGAGERSYSFEFFPPKNEAGERTLWNAIRRIEQYAPTFVSVTYGAGGSSRDRTIGL
TKRMAAETTLRPVAHLTAVGHSIGELRNIIGQYADAGILDVLALRGDPPGDPRGPWLAEP
DGLTYASELVALIRESCDFSVGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFF
DAEDYLRLRDRVAAAGCDIPIIPEIMPATDFRQVRRFAELSDAHFPDDLAWRLEAAQGDA
DEGRRIGVDHATAMARRLLDEGAPGLHYITLNRSTAALEIHRNLAPRPVHHTPR
>A0A6A6G4H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elsinoe ampelina|TrEMBL
MERISDKIASLPQDGSYFSLEFFPPKTQQGFDNLQSRLQRMSQALRPLFVNVTWGAGGST
STKSMQLAELTQRQLGLTTCLHLTCTNMSRRLIDETLEQAKQLGIRNILALRGDPPRSEE
YMAENGDAPECEEDDSNKDFTWAVDLVRYIRQKYGDLFCIGVAGYPEGHSDQSHPEHQSV
DFDMPYLVEKVQAGADFIMTQLFYDIKAYESYEKLLRSHSSGVFKTIQIIPGLMPVQSFQ
ILRRTTKLSHAKLPEPILKRFEEVKSDDEAVKRVGVDIISEMVESMKTSTQNQPKGFHFY
TLNLEKSVAQILQRCNLIPPSTPSIMTSLDYAISEEDSDGYLLVKSTDQERRRRVSREAN
NRIIVDRSRAASTHSSLYEASEDEAGKHSELPPSRAAALAISEGEGSLGREATWDDYPNG
RFGDARSPAYGEIDGYGVSLHVSIPQALRLWGRPATKDDITGIFERYVRGELEAIPWSED
ALNAETATIRDELTTLIKKGWWTIASQPAVNCARSTDKIFGWGPNNGFVYQKAFVEFFIP
SSDWKRLKEMLDQDEQFTYFAADDAGEFEASNEDSVNPVTWGAFTGKEIVAPTIIEAMSF
KAWAEEAFGIWREWGVVYKPGSATSKLLKSIREEYWLVNIIHHAYVEPKELWETLAKF
>A0A6G7XW12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. HDW12B|TrEMBL
MSGGGRRVRDLLATGERSFSFEFFPPKDAAGVTALWKALRELEPLRPTFVSVTYGAGGSS
RDTTIEITQRIARETTMTPMAHLTCVGHTRDELRSIVGAYADAGVRNVLTLRGDPPGGPG
TAWTPTDGGLTYADELVALVRSLGDFSVGVAAFPEGHRDAADLDADIAVLRRKQDAGAEF
AITEMVLRASDYFGLLERARAAGVTIPVLPGIMPITNLRQIARMAELSGREVPADVVARV
TRFEGDAEAVRAEGTAIAAELCEELLRGDAPGLHFYTLNRSRATREIYADLALPVA
>A0A7K0FP94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter puniceum|TrEMBL
MKITDHIKNAKGKTLFSFELLPPVKGQSIQWIYDAIEPLLEFKPPFIDVTSLREDYIYKQ
KENGLLEKLSYRRRPGTIAICAAILNKYKVDAVPHLICGGFTKEETENALLDLQFLGIDN
VLVLRGDARKADSSFIPTPGGHAYATDLLEQVKNHNAGKFLHEDVESEYKSDFCIGVAGY
PEKHFEAPNLATDFKYLKKKVEMGADFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLK
PISALSQLVNLPKIFHIDLPEDLCDAVQSCKNPKDVKQVGTEFMIKQCKELMDFGAPVLH
FYTMGRPEQTRQIAEAIF
>A0A1I0TIL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter suwonensis|TrEMBL
MKITDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QANGLLQKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHCYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMNTDFKYLKKKVEAGAEFIVTQMFFDNQKYFDFVKKCRENDINIPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNNEAKEIGTEAMIKQCKQLIDFGAPVLHF
YTMGRPEQTKQIAKAIF
>A0A1G5TX24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira sp. Nsp18|TrEMBL
MESQKKFAPTFSFEFFPPQTPEGVEKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETV
LEIQTEGYVAAPHLSCIGATSENIRDMLQKYRAGGIRHVVALRGDLPSGMAQGGEFRYAN
ELVAFIREEFDDTFHIDVASYPEYHPQCNSAQEDLQNFKRKVEAGADSVITQYFYNADAY
FSFIDACEAMGISVPIVPGIMPINKFSQLARFSDACGAEIPRWIRKKLEGYGDDSASIRA
LGLDIVTDLCDRLLNAGAPGLHFYTLNSAGPTTTIWQRLGL
>A0A1M3CK25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrobacter sp. 62-23|TrEMBL
MIDPSAPVHDDIAAQRRPAISFEFFPPKTEEMERNLWNTVTRLAPLDPSFVSVTYGAGGS
TRERTHSTIARILSETELRPAAHLTCVGAARGEIDEIVSRYRDIGVRHIVALRGDPPGGI
GTVYSTHPEGYRSSADLVAGIKRRHGDIEVSVSAYPEKHPESPDIDADIDVLKAKVDAGA
TRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFRQARNFVTRAGTTVPSWLAE
KFEGLDDDAETRKLVAATVAAGQVQKLAKRGVDAFHFYTMNRADLVFTICHLLGIRPDAA
RKAA
>A0A1I3J6I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halpernia frigidisoli|TrEMBL
MKITDHIKNSPEKTIFSFEILPPLKGQNIQSIFDAIDPLMEYDPKFIDVTYHREEYDYIE
REDGLLEKRVVRKRPGTVGICAAIQNKYHVDAVPHILCGGFTREDTENFLIEVDFLGIQN
VVALRGDAVKTETYFKPEKNGHIYAKDLVEQIAQMNKGKYLDETLQNSSCTNFNIGVSGY
PEKHMEAASFQQDLYHLKKKVEAGADYIITQMFFDNSKYYEFVDNCRAAGITVPIIPGIK
PLVTKSQLSMIPHRFSVDLPNDLVIAIAKSKDNKEAKEIGIEWCIEQSKDLIKNNAPVLH
YYSMGKSANLERVLKEVF
>A0A809GIL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Mycobacterium] chelonae subsp. gwanakae|TrEMBL
MTTNPLDHDASVAELQDPGSIADRLAGVQPGDVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVEELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDLE
RDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEERLLRAAGDGPEEDRDEVRKVGVEVATSMAARLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A6I9RB05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elaeis guineensis var. tenera|TrEMBL
MKVIEKIRAAVEGDGRTVFSFEYFPPKTEEGVENLFERMDRMVAHNPAFCDITWGAGGST
ADLTLEIANRMQNMICVETMMHLTCTNMPVEKIDHALDTIKTNGIQNVLALRGDPPHGQD
KFVQVAGGFACALDLVQHIRSKYGDYFGITVAGYPEAHPDMIQGEGGATLEAYSNDLAYL
KRKVDAGADFIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
RIPPEITAALEPIKENEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPTNVFRAKEDVRPIFWANRPKSYIARTLGWEQYPHGRWGDSRN
PSYGALTDYQFMRPRARDKKLQEEWAIPLKSLNDIKERFMNFCLGKLRSSPWSELDGLQP
ETKIIDEHLGEIILKGFLTINSQPAINGEKSDSPTVGWGGPGGYVYQKAYLEFFCSKEKL
NLLIEKCKGFPSLTYVAVNREGECLSNIAPNAVNAVTWGVFPGKEIVQPTVVDPASFMVW
KDEAFEIWTKGWACLFPDGDPSSELLEQVQRNYFLVSLVDNDYVHGDLFAAFKDI
>A0A024UVY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces invadans|TrEMBL
MGKIIDRLMELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPRDQLREILKNVRAAGIRNILALRGDPPIGSE
RWKPVPGGFHNAVELIRFIREEHGDWFCIAAAGYSEVHSEAWNNPNLPPSDQARQLDMIR
LKEKQDAGADFIITQFFFDVDKLLQWIRDCRQLGISIPILPGYLPIQTHNSFLKFTNWCK
TSVPPQVQEALVSIKNDDAAVKKYGIQLAVDTCKKLIANKLSLHFYTMNLARTVRAVLEG
LHLIERERGLPWGAPIMRNKDGSLEKSIEQVRPIFWSNRASSYIARTSEWDDFPNGRWGD
RTSPAYGELSEYYLAYKRPKVARDQLWGRPQTEEDVWNVFVKFIEGSVKQLPWCEQGLSG
ESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPRLM
QRLVVALADYPNLSYHAFSANGTEYTNSPGPSVTAVTWGVFPGKEIIQPTVVDTASFAAW
KDEAFELWLSQWASAYEPETVSHQLIKRIYDSYVLVNVVDNDYTNEDSDIFKIFAQVITE
SMTKDDLRQRVLELEGKNEKLHETVAKLKIIQVRSPRLVAELVTILFPM
>A0A3M6KF81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosopelagicus sp|TrEMBL
MTIRYEINPPKITDPPSRIQILDERIEQISKFCDGIHVTDSVLGIERISPLIIGAEIKQK
FPELQVTISLRVIDKTIAQIVDLADAAAHANLDGILILMGDPSPENDYKSGVIPSAAATS
LIENGINEKINLYLSLPSKPNFEKISKKVNSNPNGFVTQVIHDVSQVRRLSDYLTPKNFQ
IIPCVLYPSPKNSRSAEFLNLDWSNYENNFSSFVLEIESITGDVLVTSPNDFKGALDFLT
RLQK
>A0A2A7BA79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MMNIRELLQTRPLLFDGAMGTYYKAAPGVECEQANLTDPAGVLAVHREYLAAGADAVKTN
TFSLPRLAAAHAPGWEQLAQAGWQLAVQAAGETGAAVFADLGPAPDTEAVPAGQVYTAVA
KQFAALGARNFLFETLSSDAGLLDAVGAIKAEVPDAFVLVSFAVLPDGYTREGMYCKDLA
RRMQESGIVDAVGLNCVSAPGAMRTLAKQLGGTLPLSVMPNAGYPVVTRTQVKYQGRPEY
FARELGRLAAEGTVQILGGCCGTTPAHIAALRAELDSLPVVEKTAPAEEFSTVKEQTVEN
EDAFLRKLNAGGKVIAIELDSPRNADLTGYLEGAKKLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGLCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPGPMTVFGALNLNARNFDVELRRAKEKLENGMSGFL
TQPVLSTQAVENLKKSRETLGADAKILAGIMPVVSQRNAIFMENEINGIHVEDWIIEKFA
GLDRAQGEELGLAISLEMAKAALPYADGLYLMTPFNRVALMERLIGRLKQEVLGAY
>A0A8D3CFX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scophthalmus maximus|TrEMBL
MVNQAPRGEGSWSDSSGASNSGGESSKESSRSSTPVLDADRSDRLRDKMRRRMESADRWF
SLEFFPPRTTSGAVNLLSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYC
GLESVLHLTCCNQTREIITGHLAKAKHLGLKNIMALRGDPVGADWEEEDGGFNYAIDLVK
HIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVITQLFFRSDTFLKFL
DDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITNVIEPIKDNDAAIRNYGIH
QAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVE
DVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLHM
WGEELMKEESVFEVFTCYITAQPNCSGQKVMCLPWNDEPLAPETNLMKDELEKVNRRGVL
TINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHI
VNVHGRNLTNALDFQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYE
DESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIEDMFEMLDRHVTFECC
>W9GL34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Intrasporangium chromatireducens Q5-1|TrEMBL
MVFGPCGGVRTDGTCEMLPTPCVFDALTDLPDHSVDEAPSTPSFGPLLQPPGVEWPPMIL
TDLSTPPADASALRSTVRRLAPSCDAVLVGDHQDRVDFPPSTLARLIADAGAVPWVTLAC
RDRNRITLEQELRALALDRLATVLCVTGDGRAYDVRPDITQAFDLDGTRLAGLAASLGLR
VAVAETPTAPPRALRPKRLVQKQQVGAQLGCLNHVPSVAHLTAFLEAARAAGLRMPVIAS
VVVFTDHRSAAALTALPGLTIAPERIEAVLTAADPVEAGMTAAVDEAVQLLQVPGVAGVN
LSGLASAQSMLAAAEIQADIGHRIRTARGDRQ
>A0A2D9PCC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacteraceae bacterium|TrEMBL
MEAPLFSGLPGDIEVSFEFXPPKSDKMGETLWQSVETLAPLGPRFASVTYGAGGSTRERT
HQQVVRIQNEAGIPAAAHLTCVEATREQVDDXARHYWEEGXRHIVALRGDPPDGQSRYSA
HPGGYANAAELIAGLKKVADFEISVAAYPEVHPDSSDRKADLDNLKAKFDAGATRAITQF
FFEPECFFDFRXQAAAAGIKGEIVPGIMPVMSFAAVQRMSGLCGTAIPHWMEGLFEGLDE
RPEARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKA
>A0A2G9FT70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hodgkinia cicadicola|TrEMBL
MRLSRVRNTSIARLINQTSVSFVSANSIYVKFSVERFPPRKISNLSKMLKSDLNTNQTKL
SEFNSITCSSENKNRLNSTTFLFVVLRRLCNCSIVLHNLLIQMRCMLISNTSMFHDLGMN
NMLLISGDKYATNKRRSDDVSPYKIRRLLRKKNVFNIGTGYPDNHILCSGSFQDLFTMLL
NRESGCSMHITQIFNHMDNFLRNNLRCSIFKLGSLLPGLFISSKHPLAVDINLKCGIYLT
RPVKELLESEYLDERAAFLFNMYRIIEIIKNDITWIQVFTLNKTRILKEIIWMLNDLTYY
IRYWRLTNRNECYAVMSDMHNAYKRR
>A0A2H6FCH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Abin07|TrEMBL
MSFRETLESAKFTVTAEVGPPKGTAIADMIHHMELLKGKIDAVNVTDNQSAVMRICSLSV
CKIAMEQGLEPILQMTCRDRNRIGLQSDLLGASVLGIKNVLCMTGDHVSAGDHKDARPVY
DLESVQLLKTVDSLNNGRDLGGNEMKGATAFFQGAVVTPEANPLEPQLMKFEKKIRSGAR
FFQTQAIYDIEKFRGFMEFARKFPVKILAGLVVLKSAGMANFLNNYVPGIKVPREFIDEL
KEAGKENALDTGLSITARHIKQLKDEGVCDGVHIMAIGMEDKVPVILERAGLL
>A0A2G2CGR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aequorivita sp|TrEMBL
MKVTEHIKNGNGKTQFSFEILPPLKGENIHSIFENIDPLMEFKPPYINVTYHREEYVFKE
LKDGLIEKKVVRKRPGTVGICAAIQNRYEVDAVPHILCGGFSKEETENFLIDLQFLGIDN
VMALRGDAVKSETYFTPNKNGHKYACDLVSQIHLMNNGRYLDEELQNTCATNFCVGVAGY
PEKHMEAPSSESDIHFLKKKIKNGAEYIVTQMFFDNEKYFKFVEKCRAEGITVPILPGLK
PIAVKSHLNLIPHRFKVDLPDSLVMEIVKAKDNSAVRQIGIEWCVKQSKELVKAGVPFLH
YYSMGKSSNIKEIASQVF
>A0A5E4TDV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea morbifera|TrEMBL
MTQPSFSFEFFPPKTADGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQGTLDTVVEIQR
EGVEAAPHLSCVGSTRENIREILQTYRQHGIRHIVALRGDLPSGMGEIGEFRYASELVEF
IRAETGDWFHVEVAAYPEYHPQARSPRLDLEHFANKVKAGANAAITQYFFNADAYFRFVD
DVARLGVQVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDREAIRAFGLDV
VTGLCERLLAGGAPGLHFYTLNAASATKAMWQRLGL
>A0A0M2U113|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium PH28_bin88|TrEMBL
MAGQENWKGRTCKLAKSNLQKVLELGHFAVTAEVGPPRSADFSSLKQKAEMLRGYVDAIN
VTDNQTAIVRLSSQSCCGELARMGIDPVFQVTCRDRNRIALQSDILGAVAQGARNILCLS
GDHQSFGSEPQAKNVFDLDSVQLIKVVAGMTEGIFAGGDRLEAPLEAFVGAAANPFADPL
ELRVRRLRKKIKAGARFIQTQCIYDMDRFARFMEQVRAEGLDRQAKMLAGVTPLKSAKAA
KYMRDKVAGVTVPDDVIRRMEAAQDPREEGIRICVETIQKLKEMPGVAGVHIMAIAWEEV
VPEIARRAGLAPRP
>A0A2T7UB77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans planktonicus II-D5|TrEMBL
MFEGVVMSGLKLPISLEFFPPKTPEGAEKLRGVREKLYALKPEFCSVTYGAGGSTQEGTF
STVSAILSEGVAAASHFSCIGATKASVREELATLKAMGVKRLVALRGDLPSGYGAGGEFH
YASDLVSFIRTETGDDFHIEVAAYPEIHPQAKSPEADLQAFATKVKAGANSAITQYFYNS
DAYFRFVDDAYKLGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGYGDDIES
IKAFGLDVVSDLCEQLINGGVPAIHFYTMNQSAATTEILRRLMDSAP
>A0A1Q5AYK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MJM1172|TrEMBL
MALGTASTWSDRAHTVRDLLASGSSYSFEFWAPKTEKGERNLWEALRRVEAVAPSFVSVT
YGAGGSTRGGTVRATEQIAADTTLTPVAHLTAVDHSVAELRHVIGQFADAGIRNMLALRG
DPPGDPMAPWVKHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVDK
CRAGADYAITQMFFHPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
DAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A437UUI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriales bacterium OH1046|TrEMBL
MRISERLAAKQTFSFEIFPPKGDLPIDQALAVAGALAADKPDWISVTFSAGGSGNSANTL
AVAGELLKRCAIEPLAHLTCMGSERADIDAYLAALAAAGISNVLALRGDRIPGREVADFA
YASNLIAYIKHVAPEFCIGAACYPEGHVECEDFELSMRHLYAKQQAGADFFVTQLFFDNE
LFYTFREACTRHRIKIPIVAGIMPFTSAKQIQRMAFTCGATIPAAVIKRIVSAGDDPADQ
ARAGLEYALEQIADLAANGVDGIHIYTMNRHEIGDAAYDALLACGYLED
>A0A091PXA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptosomus discolor|TrEMBL
MVNETQHTCSTSSSSKSDAGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLCQLVKLSKLEVPQEIKDVVEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>J8I593|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus (strain VD045)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8D8CPL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Culex pipiens|TrEMBL
SFVSILSRGSVSFGRLSFARNLSADVLVWWLSSSRDLLRTARGTRVTVEKRTEKRLRGLN
LSSPSREKRRPPPTSPMHRQTVESDPNGEEDKSTILAAGAVTAEVMHSHENSRNLKQVIQ
RWTTSERLCYSIELIPREDFHLDLGRLAPVFCSLPWISDNNLQYQRFVDTPMLKMTAKIV
PRCPVMNHLSCYNITETQVDKFVDMGNWNLFVIRGDTVSEGQRFQHSGDLVEYLRAKNNP
DLTIGVGGYPYGHPESPSVDYDVKYLKQKVDLGVDFIVTQTLYDAASFLAYVDECRRSGI
TVPIVPGLFLPGSPDQLETVLALTRVNPPAGVRDLLQSHAHDEPDQFEAFVVKHFAELIR
TLRRERPDEVRLVHFFTFNRLDLLKKVLDAIADLL
>A0A7D9H338|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dekkera bruxellensis|TrEMBL
MSMKITDKINALDKDEPFFSFEFFPPKTEHGMRNLYARLGRMSLMGPLFVTVTWGAGGTT
AEKSVDLAITCQKELGLTTCLHLTCTNTTKKIIDKALASAKAAGIRNILALRGDPSRTSE
VNKLSKEEAPFQYAVDLVKYIREQYGDYFCIGVAGYPEGHADGFYDESQDPHKDMPFLVE
KINAGADFVLTQLFFDDRSFINFDALLRSQADLKNKEIPVIPGLMPINSYDVFKRATKLA
HATIPDSVLGRFSEEIQCDDDRVKEIGVDIMTEMIEDIHEKTSVHTRGFHFYTLNLEKSI
AQIVNRSSLLSQVVDKKERELEECVSDSSDDEIDDNVTTAKRAAYMNRFKQPTNQIIVED
GKHKDSAAKTLASRQIKRRSSSQFQKIMSISSGHGALGKDATWDDHPNGRFGDTRSPAFG
SSGYGPYGPSLHVTPEKAFELWGQPETMDDVSSVFVNYLSRKVDAIPWNEMSINPETALI
QEPLIILNQHHRFTMSSQPACNCAQSADKIFGWGPAHGYVYQKAYVEMFVSKEDWKKNIL
PKLKGNPDVSYYVGDSKSYFDSSLKAKDTNCVTWGVFPDRQIVQTTVVNEDSFKAWKDEG
FQIWREWMMLYPGNSPSANVLKEVLDGYYLTAIVHHDYPDEDALWDLLVGDTE
>N0B272|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. 1NLA3E|TrEMBL
MSFLTKLENQILIGDGAMGTLLYSYGKDICLEELNLSRPEQITSIHQAYIDAGADIIQTN
TYAANYLKLARYGLEELVKEINTAAIRVAKQATGGKSYILGTIGGNRGIKPHSVHIEEIK
RSFREQLFCLLVEGVDGILLETYYDREEIETVLNIARRETELPIIAQLSMQEVGFMQDHT
PISEALGRLEDLGADVIGLNCRLGPHHMLKALEEVPLPKHSYLSAYPNASLPTYTDGVFH
YEGDAEYFRKSAMLFRDQGVRLLGGCCGTTPEHIRAFSEELRNVAPITQKTNKPKQQPIA
IKPVTSKRDAPPLQDIVKERPSILVELDSPRKLDTTRFFAGAKALKEVGIDAITLADNSL
ASPRISNSAIGHLVKTQIGLRPLIHITCRDRNIIGLQSHLMGLHTLGLNDVLAITGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSSSGKDLGQKTSFSVASAFNPNVRSLEKAVL
RMEKKIAHGADYFITQPVFSEEKLLEVYEATRHIKVPIYIGLMPLTSYKNTEFLHHEVPG
IKISDSIREQMAKYKDDPNQATREGLAITKALVDTAIELFNGIYFITPFLRYELTVELAD
YTNKRIAQLTRGKSNVQSIIQ
>A0A7S7J2G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKIKELFDAKKTVISLEIFPPKLTSPVETVFKTLDELKDINPDFISVTYGAGGKAKDRTV
EIASKIKNDYHIESLAHLTCISATKEQINGILHELRSNGIENVLAMRGDLPEDPDFEFPD
PLHYEHASDLIRQVKAEGDFCIGAACYPEGHVDCENKVQDVKYLRDKVSMGADFLISQLF
FDNELFYRFMEEIDLAGIDVPVSAGILPVLNKSQIERITKLAGCQLPPKFVRILDRYEDN
PAALKEAGEAYAIEQIIDLMAWGVRGIHLYTMNKPDTAQRIIGNIENIRRLQG
>A0A7C6J6R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKITELLKSDKLTMSFEVFPPKTDTSFESVKKATEEIAQMRPAYMSVTYGAGGGTSKYTL
DIAQNIMKTCGVPTLAHLTCISSDRDTIHQRIKEIKEAGIKNVLALRGDLTPELMLDRSG
CDYQYAAELVRDLKESGADFCIGGACYPEIHIESKNYREDIAHLKEKVDAGCEFLTTQMF
FDNNIFYNYMWKLREAGINVPIIPGIMPITNGNQIDRAIKLSNSFMPRRFRMLVDKFGDN
PDAMKQAGIAYTTEQVIGLYANGIKNVHIYTMNKPDIAKALLENLSDILG
>G8S9R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)|TrEMBL
MSLGLPSRLPGTPSIGDLVRGAAPTFSFEFFPPKTPDGERLLWQAIRELESLRPSFVSIT
YGAGGTTRETTVAVTERVATETTLLPLAHLTAVDHSVADLRNVIGRLAGAGIRNVLALRG
DPPGDPMGEWVRHPDGVGYADELVRLIRESGDFSVGVAAFPHKHPRSAGVKDDTRNFVRK
CRAGADYAITQMFFDADEYLRLRDRVVAAGCHTPIVAGVMPVTRMATIARSTQLSGAPFP
PALLRDFERVAGDDAAVRELGIETCAAMCARLLREGVPGIHFITMNRSTATREVWQRLAP
AEVAASA
>A0A847TH18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sp. Ak27|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPAFINVTYHRSEHMFKKK
ADGSFEKVEIRKRPGTVGICAAIMNHYTVDAVPHLICGGFSREETENALIDLNFLGIDNV
LVLRGDAPKNETFFEPDPHGHSYAIELLDQVAHMNNGVYLEDDLQGGVKTNFCIGVAGYP
EKHFEAPNMQTDLAHLKRKVENGADYIVTQMFFDNQKFFDFVTKCREMGITVPIIPGLKP
LTSRKQMTMLPRIFHVDIPADLSTEILKCKTDKDVELVGTEWLIAQSKELKAFGVPVLHY
YTLGKPKVIQKAVAAIM
>A0A6I6E0A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leclercia sp. 119287|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMAKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3D0IDR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKVSEIYKNKKKSLSFEIFPPKKDTELDNIDETLSVLSELHPDFISVTFGAGGSSNCNRT
IELAKKIKNEYEIEPVVHLTCLHYDRSEMEEFARILSDEGIQNVLALRGDRNPRIPEKDD
FKHSSDLISYLKPEHDFCFLGACYPECHPESSGRVSEIRALKSKVNAGAEVLISQLFFDN
DKFFQFYEECQIADIDVPILPGVMPVINAAQIQRMISMCNATFPERFQRIIRRYENNQEA
LFDAGMSYCLSQIIDLLVSDIPGIHLYTMNNPVVARRICEGIKNIV
>A0A355JAR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKLSELFKQKKATLSFEVFPPKSWDAYNNVKTATEEIARLSPDFMSVTYGAGGGASATSA
SIAENILKNFGVTPLAHLTCVSSTKQAVREYLAELSKNGIENILALRGDIPNEGLTVQEY
RYASELILDIKAAGNFCIGGACYPEGHTESKNQKEDIRFLKEKVDMGCDFLTTQMFFDNN
ILYNFLYKIREAGINVPVVAGIMPVTNGKQIQRIVKLSGTYLPQRFKSIVDRFGDNPSAM
KQAGIAYATDQIIDLVANGVENVHVYTMNKPDVAAQIQANLSEILK
>A0A5A7SEJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus cavernicola|TrEMBL
MTLESVSGARASATPSIVDRLRCDDTGRVPFSVEFTPPRDADGEARLWRTVREFERLRPA
FVSMTYGAGGSTSDRTVRITGDLAEATTLLPVAHLTAVGHSIAELRSMVGSYADRGISNI
LVLRGDPPGAPLGEWTMHPEGVRYADELVRLVRDLGDFHVGVASFPEGHYRSPDLQHDTK
YLVAKLRAGAEYSITQMFFDVEHYLRLRDRVAAFDPEQGAKPIIPELMPITSLGSVRRMV
ELSGSALPAELETALALAAGDGPVEDRAAVREIGIERATLMGERLIAEGVPALHFITLNF
ARATSEVLANLGLGATQPVRN
>I0AHI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacterium album (strain DSM 19864 / JCM 16511 / NBRC 101810 / Mat9-16)|TrEMBL
MKVIEHLSNARNPLISFEIIPPKRGGDISSILSLLDDLVKYHPPFIDITSHAAEVYYDET
PQGIKKIIKRKRPGTLGICALIQNKYNIDAVPHVLTKGFTREETEDFLIELNYLGIQNVL
AIRGDDSGYNKPIPQGRSANQYAVDLVKQIMDMNRGKYLEDSLLDAKATNFCVGVSGYPE
KHFEAPNLKSDIKFMKEKIDAGAEYIVTQMFYDNKHYFNFVELAREMGVTAPIIPGLKIL
TSKVQLNTIPKNFYINIPEALSDEVLAAKPEHVIDIGVEWAAKQVEELLNKNVPAVHFYI
MQNSKPIIKLMEKIKL
>A0A435DEH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.005.03.1.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQAPTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYIDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAEQSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A5E4VUH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea fibrosis|TrEMBL
MSGSLDNKTIMTKPSFSFEFFPPKTVDGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQG
TLDTVIEIQREGVEAAPHLSCVGSTKENIRAILKTYRDNGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGDWFHIEVAAYPEYHPQAKSPRLDLEHFANKVKAGANAAITQYFF
NADAYFRFVEDAQQLGVTVPIVPGIMPITNYSQMMRFSEMCGAEVPRWVAKRLEGFGDDR
EAIRAFGLDVVTALCERLLAGGAPGLHFYTLNAASATKAMWQRLGL
>A0A3M8ADV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces tardus|TrEMBL
MTGSDVDGTDCRPRPPISFELFPPRTDAAALALGRTIDRLAEVCPAFISVTFGAGGSSRD
RSLTVLRYMLEHTDVQPMAHLTCVGSSHAEANRLVREFLDAGITSFLALRGDPPSGADAD
ADAGIRDLGSAAELVQLIHRVQEEREPFGQSGIPGMPGATRIRERPRPERVAVAAFPTGH
PRSRGLSQDVDNLLAKEIAGANLAITQLFWHADDYLAFVERARAGGVTIPILPGIMPVTT
PARLARLEELTGVPAPSELAISLEIEPDADAQFDLGVEYAARLADEVLAGGAPGLHLYTF
NRHEAVLAVLDRLGIRTPAQLTTERNTRQR
>A0A3D4MVG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MNVAEIMEQRNAFSFEVFPPKTDVGMEKLCGEGGVLEKLYTLNPDYISCTYGAGGTNVGK
NLEVLKKIKADGKCTPVTHFTCVANTKEGIKDQLQTYLDNGIDHMLALRGDIPFGWTGTN
GDLHYATELVKFVRKEFGDKFTIAVAGSPEGHIACRSLEADISFLKQKQDEGADYIMTQL
CWDMDQFRYWMDAIRAAGIWLPVDVGIMPVLDAAATINMALSRNGCVMSRDLCEIISKHW
IFPNPFAPNESEESIAAKKASFKEAGIEYTIKLIDEYRVCGINGIHLYALNKYDDVARIV
KESGIVDLI
>I4YIV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66)|TrEMBL
MKITEKLLAAEREDRLWWSFEFFPPRTAQGMTNLVDRIERMRRLGPEFVDITWHSGGRTA
ELTTELVKTCQASIGVETCMHLTCTGMPREKVINALEEAKKNGCTNVLALRGDPPRGQTE
WYPHPNGFTYAADLVRHIRQEYGDYFEVAVAGFPEGNLQYKHSSDKDNEIQYLKEKVDAG
ADLIMTQMFYDVDNFIDWCNKVREAGVTVPIVPGIMPIQTWNGFQKAVQMAQTKVPQDWM
DQLEAVKEDDAKVREVGTKLVSDMCRKILDANVGIRGLHLYTMNLERGPKMILQELNLIP
QTQILNPLPWRPSLTPTRRAENIRPIFWANRQKSYLSRTEMWDEFPNGRWGDSRSPAYGE
IDGWGPTINFKLDEAREIWGEPLKYDDVCNLFSRFCLNDLKALPWSDQPPARETSVIDRQ
LAMMNKIGFFTINSQPAVNGARSDDPVHGWGPKGGYVYQKAYLEFFVSPDNLDKLISRIE
LNPMMTYYAVNRRGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELG
YQWSDIYEKGSTSQQLIKDIMDSHFLVNVVHNDFKNGQDIFKPFLDEIANESAIKDTTKN
>A0A449G8Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia farcinica|TrEMBL
MVQSLRAHAGRSVPFSVEFNPPRDAAGEARLWRAVREFERMHPAFVSMTYGAGGSTKDRT
VRVTGQLAQETTLLPVAHLTAVGHSVAELRSLVGAYADSGIRNILVLRGDPPGDPLGEWH
KHPEGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLATDTAFLAAKLRAGAEYSITQ
MFFEVEHYLRLRDRLAALDPVEGAKPIIPELMPITSLRTVTRAEELCGRPLPAAVLDRLR
RAAGDGPEEDRAAVREVGIEIATEMAQRLIDEGAPCLHFITLNFAKATSEVLTNLGYGVT
AAPVRA
>A0A3C0NLL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
DGGADVITVADCPIARARMDSSLMVCKIKRELGVNVMPHLTCRDRNLNATQALLLGLCAE
DVNNVLLVTGDPVPAASRDEVKSVYNFNSRKLIKFVDSMNRAVLPAPFHIFAALNVNARN
FAIQLDLARQKEENGADGFLTQPVFTDEALENLRLARRTLKGKILGGILPIVNQRNALFI
NSEIAGIRVDEETIARYENADRARGEELAVEISAKLARRMAPYVDGYFLITPFSRTELVV
RIMERIRADAAE
>A0A1Q6F8Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium 43_36|TrEMBL
MKVIDLIRDSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNDKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFAIELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A315EXN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans curvus|TrEMBL
MNANNSLSIEFFPPKTPEGAEKLRVVRQALYPLQPQFCSVTYGAGGSTQAGTISTLKEIL
SEGVPAASHFSCIGATRDSVRQQLAEFKAMGVKRLVALRGDLPSGYGAGGEFHYASDLVA
FIRAETGDDFGIEVAAYPEIHPQAKSAEADLQAFATKVKAGADSAITQYFYNSDAYFRFV
EDADKLGVHIPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLLGFGDDLASIKAFGLD
VVTDLCDQLRAGGAPGLHFYSMNQSVPTLAICKNLGLGV
>A0A6L8A9S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGGADFHLSFEFFPPSSSDGWKQLLRTARRLQDEKPDFFSVTYGAGGSTKSRTFQTVKDL
RSQGFNVNPHLSWGDVSREEISSTVQSFLELGVDGMVVLRGDSPLGSMRSVMHNASELVQ
LIRNDLSKELKIFVAAYPEMHPDAPNPSKDLHFLLEKVQAGANACITQYFYNADAYLNFV
DRCTNFGISVPIIPGIMPIYNYDQLVRFSQNCGAEIPRWIERGMHEYRTDKNALEEFGID
VVTQLCERLRSEGAPGFHVYSLNRALIPKRILRNLDLQR
>A0A7C1XXH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MESQKKYTQQFSFEFFPPKTDKGIEKLKLVRDQLGTLKPKYFSVTYGAGGSTQQGTFDTV
MAIRQAGFDAAPHLTCVGASRQSLRELLQQYVDNDIHRIVALRGDMPSGMHTSGEFHYAN
ELVAFIRAETGDHFHIEVAAYPEFHPQAVNAQRDLDNFKRKIDAGANSAITQYFFNPDAY
FRFIDDCERLGIEVPIVPGIMPITNYSNLARFSDMCGAEIPRWIRKRLEAFADDTDSIKA
FGEDVVTDLGHQLLEAGAPGLHFYSMNQAEASLAIWKNLGL
>R5M798|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides intestinalis CAG:564|TrEMBL
MYKRIAQQIKAYLISFSYFCSQCTNKFCSPNKDNEKEMRIIDLIHSNEKTAFSFEILPPL
KGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDLGNGLFQRNRLRRRPGTVAVAAAI
QNRYNITVVPHLLCSGFTREETEYVLLDLQFLGITDLLVLRGDKAKHESVFTPEGDGYHH
ATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYPEKHEEAPNIDTDIYWLKKKMEAG
AEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKPFKKISQISMIPKTFKVDLPEELT
CEAMKCKTDEEAKQVGIEWCAKQCKELVEHGVPSIHFYSIGAVDSIKEVAKLVY
>A0A429IV97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lactucae|TrEMBL
MLVEYLTSLNEIYPVKHEFAGFPAAMTLADRVHSDHDIAPLEASKSYPDSIDKVLHFSGK
ARDIQDFECFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHHYSQ
QILACVMPLTLARANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWHVTTGKEFSPEIACFSR
QPTSKQLIKYRQLHVMHEAMFVSKIAKGVGRFIFKASFWENSLVAKVLLKTEVLSKHSLV
GCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQT
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A6J5E3D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia humisilvae|TrEMBL
MNPIELSFEFFPPKTQEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVIDMAQ
GGLEAAPHLSCIGSSKESLRAILNQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFCIEVAAYPEYHPQSRSPRHDLENFARKVKAGADSAITQYFFNADAYFHFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDREAIRAFGLDV
VTRLCQRLVDAGVPGLHFYTLNGAAATKAICERLGL
>A0A8I0D237|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas tritici|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVNAGIDLEIIPGILPVSNFKQAKKFADMTNVRIPLWMQKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7K5C4C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Motacilla alba|TrEMBL
MVNETQHGCNASSRSDGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDKWFS
LEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIAYTAVNYCG
LETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVKH
VRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVCAGADFIITQLFFRPETFLKFMK
DCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVEL
AVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWNEDPRRPLPWAVSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGILT
INSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIV
NVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEE
ESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>E4ZHE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)|TrEMBL
MHISKKLAQAREDGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDITWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALRDAYQSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIRERYGNHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGATF
IVTQMFYDTDIFLEWVRKVRAKGVDVPIIPGIMPIHTHAAFLRRAQWTRCNIPQHWTEAL
EPVKNDDVEVREVGKGLVADMCRKLIDAGILHLHFYTMNLAQATRMVLEELELLPDQRSP
LEKPLPWRPSLGLNRREENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPISIRDFSDLFVRYMQGKLDSLPWSEQPITNEAGSIQDDLID
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVLVSPEYIGEIISRIERDE
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHSSVSPARHAVQKVVDTWYLLNIVHNDFHATRGIFPIFDGLAVKDMDKPIQSLSGEV
ATSNGQEATRETNSTNGADAAKGADGTNGANGTSGTLPEYSTMEDANLIDAAKSAAVEVT
NKVKKLALSN
>A0A352KPB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDSQKKYPQHISFEFFPPKTEEGEKKLLQTATQLTKLNPHYFSVTFGAGGSTRDRTFDTV
LSLAKATGIPLAPHLSCIGSSKAQLLELLNQYRENQIDRLVALRGDRPSGDVAKGELNFA
YELVQFVREQTADHFHIEVAAYPEFHPEAVNPQADIDNLKRKFDAGANSAITQYFYNAEA
YYRLIDACEANQIEMPIVPGIMPIMNFTQLSRFSAACGAEIPMWLSKRLAA
>A0A2E3WC18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNRHFSFEFSAPRSPEATEKLLQVHDRLQVCHPDFFSVTYGAGGSTKDGTRQAVLTINEL
GSNVAPHLSFGGDPPEKIEQLLHDYQNAGIKRVVALRGDIPSGQMTKMTYANELVSFIRD
KTGDHFHIDVAAYPEIHPESTSVESDLMFFKNKVDAGADSAITQYFYNPDAYFRYLDACA
ALDINIPIVPGIMPITNYQGIVRFSKNCGAEIPRWILKHLESYEDDPESLKAFGLDAVTK
LCHRLLEGGAPGLHFYTLNQSLPTIHIWRNLDL
>A0A2A4VN30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSYSHARQIESLNRSLSETSKDIQVSFEFFPPNSPEMETTLWNSVERLAPLKPNFVSVTY
GAGSGTRDRTHEIIKRIQKDTALIAAPHLTCIDATKEELVEIAKDYWASGVRHIVALRGD
LPNSDEKPSMYASDLVELLRGVADFDISVAAYPEGHPEAPNPQFDLLNLKRKIDAGANRA
ISQFFFDIEAYLRFRDRCVTVGIDVEIIPGILPVTNYKMLERFAGLTNVHVPSWMPKMYE
GLDDDETTRRLVGANIAMEQVKVLSREGVKNFHFYTLNRAELSYAICHTLGIRP
>A0A3C1TX92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTSKRAHISFEFFPPFTSKGQKSLLKVAKRLNTFKPEYFSVTYGAGGTTRERTYETVSSL
>A0A3C0YFP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MALTQPKVATCLPPLSFEFFPPRDEESIDRLVSGTACRLGAYAPEFFSITYGADGSSKEG
TLRSVAALLEANRNTAPHLSQGSDTDTAIIELINRYLALGVTRLVALKGDARKAGDRRPV
YARDLVRTIRQHFGDALRISVAAYPEVHPDTASLDLEMKFFVEKVNAGADEAITQYFYNP
EAYANFLDHCARMGLDLPIVPGIMPITNYQGLMRFSERAGADIPRWLDRTLRDKSDNVAD
LCAFGDEVVTNLCERVIQMGAPRLHFYSLNRWGACSRICDNLGYVKT
>A0A293NAT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSSEELILSQTDHSSSQPSLSFEFFPPRDEDGIAKLLQGAITKLATFNPDYCSVTYGAGG
STRQGTQDLVQAMLATKISAAPHLSISGSSDAALDQLVEYYQEIGVTKILCLRGDQPSGH
ASKPAYAKDLVERLQQRFPKQFELAVAAYPEVHPDASSAEDDLAHFVAKVNAGASSAITQ
YFYNPEAYGYFLDRCAKAGVSIPITPGIMPITNINALQRFSAKAGADIPRWLAKSMFSYA
SDGKGLVDFGVEVVTKLCERLLELGAPGLHFYTLNRWGASSQLCRNLGFLER
>A0A5J6V9E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ornithinimicrobium pratense|TrEMBL
MSNKRPPPALKSLLLEARLEVLPSGGIVDRVHEHVAPGRTVTVTASPTKGLDATLEVTER
LAQRYRVVPHLAARMVPRAGLPDLVSRLQEAGVTEVFVPGGDASGTVETFDSALDLLLAL
DELGRPFEQVGITGYPESHPGIEDHVLVQSMWDKREHATAIVSNMTFDHAMVGRWLESVR
DRGVTLPVHIGVPGPVDPGKLLRMATTIGVGDSMRFLRKQKNVFARIALPGFSSTTFVRK
VAQLAADERLGIRGLHIYTFNQVGRIEAWRREQLDRL
>A0A3C1TY98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
QFGIEFVSRLCERLLAGGAPGFHFYTLNKAKSSESIAENIGFLENI
>A0A3D5FDR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGNALSGTPTLFPGAVTNPGAADLDAEIDNLQRKAAAGACFFQTQAVYDAEAFAAFLEKA
RLEQPMLAGIIPIKSVKMANYMNERIPGVEIPDALIARIADAGDDPKRVAQISIDIAAET
VRKLKPIARGVHLMAIGWEKHIPEILARAGV
>A0A496WG65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
VYARAQVFDGFVDGMNATDGSGANCHMSSVAMCALLTNIGYSPVMQIACRDKNRIAIQGD
VLGAAAMGVSNVLCLSGDGVQVGDHPEAKPVFDLDSMSLLETIRIMRDESRFLSGRKITT
PPDIFLGAAANPCAPPIDFRPYRLAKKIAAGADFIQTQYIFDVPQLKEFMLKAGDLGLLE
QCFILPGVGPLASARTATWIRDNVPGIHIPDDVIKRLAGAENQKKEGQKICIELIQQIRE
IEGVSGVHVMAYRQEEAVADIIKQSGVLEGRVPWYPGCEELEQA
>A0A2D5LFK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTPVSFEFFPPRDTAGREKLTAGTATKLAALXPEYFSVTYGAGGSTKEGTKQTVTDLMDR
GWNAVPHLSVGGTDQHGTLDLVAYYKELGVKKILCLRGDQAESDAHNPQYAEDLVRLIRQ
HFGDRFEIVVGAYPEVHPDSTSSQDDLMFFKRKVDAGADVAITQYFYNIEAYGYFIHQCQ
SLGIDIPIVPGVMPITNYASLCRFSEKAGADIPRWLDRAMAQRQDSDQELGKFGVEVVTR
LCEQLIELGAPALHFYTLNRWGATTKVCANLGLNVS
>A0A3D5Y5T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSRAANLAEPGTGFKSDSHLERVLAGGHFAVTGEIGPPKSWDAEVIRQKASLLKGYVDGA
NITDNQTAIVRMSSIAAGIIVKQEGLEPVIQMTCRDRNRLAMQSDLLGAAAHGINNVLCL
SGDHQSFGNHPGAKNVHDIDSLQLVQMVKGLREGHFQCDEEIKGGGPGYFIGAAANPFAE
PLEWRPFRLAKKTAAGADFIQTQLVYDIPRFREYMKKVVELGVHERTAILAGVGPLKSTG
MAKYMRDRVPGMSVPQECIERMADAVAGIDEGDKKARAEAWRTEGIQLCIEQIQEIRQIE
GVAGVHISAIEWESAIKPLVEGAGLLPRPPMNG
>A0A534B5E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPIRPGHTSPGRFERVLRAGQFAVTTELDPPDSADPEEVYRRARVFDG
YVDAINATDGSGANCHMSSLAVCALLTRVGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQALPVFDLDALTLLETARTLRDEHHFLSGRKITHAPRVLLGAAE
NPFAEPIEWRAERLAKKVAAGAQFIQTQFCFDVPLLRTFMNRVEDLGLLDKVFILVGVGP
LRSAKSAEWIRTRVPGVHIPDEVVKRLAGASDGGLEGRRLCIDLIQEIRTIKGVHGVHVM
AYRQEETVAEIIQRSGVLGGRVPWNPGRDPPANTNTNRMASGPTPSAAPQPARS
>A0A2E4GHU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MRKTLGKXSNIKGXEXARRSGPFSVREXINVSFEFFPPSSEKLAQQLWESIVLLEPLKPS
FVSVTYGAGGTTRQRTLDTVKRIVAETDLTPAAHLTCIGSSRENIQIVAQEYWDVGVRHL
VALRGXPXQXTDKFSPXPQGYNNAGELVSGLXEVADFEISVAAYPEVHPEAKSPEADLXN
LSYKLXCGASRAITQFFFDTEIFLRFRDAAAAKGISAPIVPGILPVTNFSRLVEFANHCN
ASIPRWLEDMLNGLDNDPNSRRLIAGWVAIEQCRQLANHGVTDFHFYTLNRAELTRAICH
ALGVRDQEMLGSSQ
>A0A2E5RI78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTLKVSFEFFPPQTDLMEERLKTNVQKLIGLRPSFVSITYGAGGSTREKTHSVIKKIMTQ
TPLNVAAHLTCVDASKNETKKVIKDYLDIGVRHIVALRGDIKDLNAFEPHPEGFRNSIEL
IEYIKSRANITVSISGYPEPHPESKGYQSDIDFLRAKIDSGADQIITQFCLNTDYYLRYR
DQLDKEGFTAPIIPGIMLIKKFRGIEKMSKKIGVEVPAEILNIIEKNLTADEEKNAAEEF
AIDQCEKLRKNGFENLHFYTLNESEIMIAIANKLGFENHAN
>A0A2S4NA59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium croceum DSM 17960|TrEMBL
MKVTEHIQNAKGKTLFSFEILPPLKGQNIQSIFDGIDPLMEFKPPFIDVTYHREEYEFKE
LPNGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKTETYFKPEKEGNEYASDLVKQISNLNQGIYLDEDLQNSAKTNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFYDNKKFFDYVAKVRAAGITIPIIPGLK
PIATKKQLNLIPHRFSLEMPDELIMEVVKAKDNDAVKQVGIEWCTHQSKELVKAGIPVLH
YYSMGKAANIKAIAKEVF
>A0A521YCA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
IHLPIVPGIMPITQFQKLARFSELCGAEIPYWIRKRLEAYGDDLESIKRFGTEVVTQLCQ
KLIGGGAPGLHFYTLNKAEAVLQILKNLNLARTSMRLGAEAIM
>A0A3M0YHF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPFSLSFEFFPPKSGEGAARLRRAYMKLAQLRPEFFSVTYGAGGSTRERTLETALEIREA
TGIDV
>A0A349KKV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSALAKKLQAGKFVITGELTPPKGTDISELQTRARSLAGCLDAFNFTDSHASKMSLSAIA
AARLLLDDGIEPILQLTTRDRNRIALQGDMLGAWLLGIQNLVCMGGDPPHLGDHPEAKPV
FDLSTEELICAAGKLNAGTDFMDNPLNQGTAFNIGAVVNPGADDLDGEIARLETKVAAGA
LFFQTQAIYDADHFTNFMERISHLDIAILAGIMPIKSVAMARFMNEKIPGITIPEELIQR
IAGATDIAAESTQIAVEIIQRIKSQCQGLHIMALGWEDKIPGIIEQANLDRGCL
>A0A3D1EMD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSASQTPISFEFFPPRDAEGVDKLIAGTAAKLKAFNPEYCSVTYGAGGATKDGTRQTVQA
LRNSGLAIVPHLSAGREENSALIALVDEYREQGISQILCLRGDQPSGEASSKRYAVDLVH
LLKNHFGDALHLAVAGYPEVHPEAVGPSADLAFFKDKVSAGASSAVTQYFYDINAYADFV
ERCAASAINIPIIPGIMPITDFDALVRFSNKAGADIPRWLGKALEERRNDEASLSALGVD
VVTKLCSQLIDLGVPALHFYTLNRWGAATKICRNLGL
>A0A2E9P595|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGAPRVSFEFFPPKTLEAEASLWKTVNRLKALCPEFVSVTYGADGSTRERTHQVIKDILT
KTSLRPAPHLTCVGTPQKEIDAIADEYWSMGVRQIVALRGDPEGGAEANYIPHPEGYAYA
SDLVQGLLEKHPFELLVAAYPETHPQAISADKDLENLKRKIDAGSRCAITQFFFDNEMFL
RFRDRVAAAQMNVKLIPGILPVTNFNTLTRFAGACGASIPQWFSTQFEGLDEDPTTRQLI
AAHAAVSQAEQLGREGVDDFHFYTLNRADLSFAVCHALGVRGRA
>A0A2D7CUJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTPVSFEFFPPRDTAGREKLTTGTATKLAALGPEYFSVTYGAGGSTKEGTKQTVTDLMNR
GWNAVPHLSVGGADQQGTLDLVAYYKELGVKKILCLRGDQAESDAQNPQYAEDLVRLIRQ
HFGNCFEIVVGAYPEVHPDSASSQDDLMFFKRKVEAGADVAITQYFYNIEAYGYFVDQCQ
SLGIDIPIVPGVMPITNYASLCRFSEKAGADIPRWLDKAMAQRQDSDAELGKFGVEVVTR
LCERLIELGAPALHFYTLNRWGATTKVCTNLGLNVS
>A0A534C3M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MQTLADRLRSREFVVTTELTPPKGLDLSELFAKAQALKDCVDGFNLTESPRARMTIEPKA
VAHLLLDRGLEPIVQVTARDRNRIALQADLLGAAALGIRNFVFMAGDPPSSGDHPDAKPV
FDLNTNEMLRAAAGLARGRDLAGNELRGAPRLF
>A0A356QZ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MATDTAADTLPDLKSGSNLEKVLAAGHFAVTGELGPPKHMDTSVVDRKIGLLKGVVDAAN
VTDNQTGIVRLSSIATGIYMAQHGLEPVIQMTCRDRNRLAMQSDLMGAYIHGIRNVLCLS
GDHQSFGNHPGAKNVQDIDSMQLIRMLQEMRDKNQFQCGDEIKGGGPKLFIGGAGSPFSE
PISFRPLRIAKKMAAGVDFIQTQMIFDMDIFR
>A0A6M0KYC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp. bin170|TrEMBL
MFEKFCKKLHSNEPFITVEITPPHGASISKTIETIKSIGLDKKVSGFSVTDNPLAKLKMS
GVLSAIKIQESFGKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKLSDQPE
VKGVLERDSTLLLSIIYRLNSGLDYSNKELNPKPKPIYPFAVSNAYSKDMRRIKKKILKK
LNYGARGIITQPVYDLDNAKELIEIFEECKEQSVRETAKEAELILGQFPVVRAKTANFIS
DKVPGITVPKDIIDEMNLAAMDGVDKEQEVGFGISKTLFDDIMNLHPKVHLMTHNRFDLC
SKLIGDKV
>A0A6H3CY31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas avellanae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A3D1AYB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacterales bacterium|TrEMBL
MFIRDLLATGRPSFSFEFFPPKSAEAAAQLEKTIA
>A0A1Y6BW84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium Bs31|TrEMBL
MSDEVQDLRLSFEFFPPKTDLGAEKLKTVRSELNKLNPDFFSVTYGAGGSTRDTTKDVVK
AMIAEGISTAPHLSFGGDHEETLYEMLDEYKNLGVDRIVALRGDMPSGMGAAMQMVYANE
LVAFIRDRFGDHFQLEVAAYPEIHPEARNYIEDVRYLKGKFDAGANSAITQYFFNPDCYL
YFVEECLKEGIDQPIYPGIMPITNYVKLARFSDACGAEIPRWIRKRFESFGDNNESIVSF
GIDLISELCETLLDNGAPGLHFYTMNQIEPTSTIVRNLGIIE
>F0S3V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurobacterium thermolithotrophum (strain DSM 11699 / BSA)|TrEMBL
MSFSKKIKNGKFIITAEVAPPRGIEWKTVIESIEPLKGKVDAFNVTDNQRSMVRMSSLAM
SKLLLDSGFEPIFQLTCRDRNRIALQSELLGAAALGIKNVCLMTGDFTTLGDQPDAKPVF
DIDSIHLIQTAKKLESGVLLNGKELKGVPNFTVGAVYNPFAGPKVLQVWKLRKKIEAGAE
FIQTQPVYDVRVAKDVHDLIESLGAIPIIGLLPIKSLKMANFMKKLNPTSIPNRLIEGLE
RANNPAQYGWDYVIDIAHAIAEFGKGIHFMLVGKTAELAAFIDYLRNNSPYNHKF
>A0A4R4Z7W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea terrae|TrEMBL
MALGRPSIRPDRVPTVRELLASGGRSFSFEFFPPKTDEGARQLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERIAHDTTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNMLAVR
GDPPHDPMGEWVPHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTEYFVR
KCEAGADYAITQMFFEADDYLRLRDRVAARGCETPIIPCIMPVTQMSTIARSEQLSGAPF
PAGLAARFEEVEDDPAAVRRLGIDHGAAMCQRLLDEGAPGIHFITFNRSSASREVFQRLE
RVPLSA
>A0A1Y0IFG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleiphilus messinensis|TrEMBL
MLRNKILNREDGIVFYGIVPPKKDTDPERVREISELQMSRLKGRSIDGMVLYDIQDESSR
TSEKRPFPFMETLDSFRYSREYLSALDVPKIIYRSVGKYTKDTLSQFIQAVDTEKELSVF
VGASSMDQDVTMTMREAYALRSQLNPELLVGGVTIPERHLTKLDEHMRVFSKMQQGCSFF
VSQGVYDVNASKNFLSDYYFYGQENGIELAPIIFTLTPCGSRKTLEFMKWLGIEIPRWLE
NELVHSEDILQKSVEFSVQSYKELRAYAAEKNIPIGCNIESVAVRKAEVEASIEMLDMIN
AG
>A0A212JIX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfovibrio sp|TrEMBL
MHIGKMIRELSAPFYSLEFFPPSDTAQLPDFYATVDRLRALNPLFASVTYGAGGARQQNT
LAVTAELARRGITAMAHLTCVGAEPQSIAAFLHDLQASGVNNVLALRGDPPADKPWDWNK
AHFRHASDLVAFAREQQPDLGIGVAAYPAPHPESPTFADDRRCTAEKMRAGADFALTQLF
FDAREYEDLVSHLRGQGITTPVIPGILPIQSFDSLRRVLSLCGANIPGKLYLALEKANND
GGAEAVRQVGLDYAVRQIRSLLDAGAPGIHLYTLNKADMCLRLAEAVGTL
>A0A1Z8V6W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium TMED61|TrEMBL
MIEDNMSALSKALQSSDFVVTSELTPPKGLDLAPXLEKAALLKPYVSAINLTESHAARMA
MDPVAVGHLMLDQGVEPIVQMTSRDKNRLAIQASILGACALGVSNLVFMGGXPPKNGDHP
DAKPVFDLFASQLLEAVQALNNGTDLNGNALNRNTEIFAGAVVNPGASDPDAEIENLHRK
IDGGAEFFQTQAVYDVDAFSNFLEKADSPKPILAGIIPIKSVKMAQYMNDRIPGVDIPDH
LIEKIAGAGDDKEAISQISIEIAANTIQELRSVTKGVHVMAIGWEQYIPQMLEQSQS
>A0A2W4JBI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermocrispum agreste|TrEMBL
MARAKGTGQEPTGKRQALEPLLARPRYEVLPLESVLTQTESLPAGSVVTVTSSPRQGLDS
TVAVAEKLAAQGMSVVPHLAARQVTGPAELRRLLDRLDVAGIGEVFVVGGDGREPRGPYP
DALSLLRAMDDLGRMPAKVGVAGYPEGHHAIDDDTLWQALRAKRDYASYVVTQMCFDADA
IGRFATDVRREAGLPVIVGVPGVVEPAKLMRIALKVGVGQSLRFVRGHRSVAGRLLWPGG
YRPDALLRKLAARIAAGRAQLTGLHLFTFNRVTATHRWVAQAYRRTA
>A0A1X0TLL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snodgrassella alvi|TrEMBL
MSFTQLSFEFFPPRTEEGRRKLAITRKQLSQYQPEYFSCTYGAGGTTRAGTLQTITDIMN
DGVAAAPHLACIGASREEMISLLQTYKDMGIRHIVALRGDVPSGVGFGHQGLRYANELVA
LIRQEFGDWFHIEIAAYPEFHPQSRSAEDDINHFVRKCQAGADSAITQYFFNADSYFWFV
DEVQGRGIDIPIIPGIMPIASFSKLARFSETCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCDHLLQQGAPSLHFYTLNQAGLVSTICQRLGY
>A0A4Y8PUQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. MEC084|TrEMBL
MARTGAEGPDPVADTTSPQAKLADDYSLEMTGKDVPGLHEAQDAIPPGTRVNVTFLGNED
LEMRVAAAQAVKEAGFVPVPHISARRLASQAQLEEFLDRLQQVGATEHVFAVGGDPATPE
GPYDSSFDVIRSGVLQKYGVREVSIAGYPEGHPDIPTDVLWEHLENKAASLAEQGLGAVI
LTQFAFDTDPVTTWIRDVRERGIDATIRIGTPGPAGIKRLLNFARRFGIGANAMIVKKYG
FSLTNLMGTAGPDRFVTELADLLAADPSSGDVKLHMYAFGGLRATAEWARDYRHRVSA
>A0A370N816|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia lacunae|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLAALKPKFVSVTFGAGGSTQQGTLDTVVEMAK
EGFEAAPHLSCIGSSKESLRAILNAYRAHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRQDLENFARKVKAGANSAITQYFFNADAYFRFVE
DAKKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCGRLIAAKVPGLHFYTLNGAAATKGICERLGV
>A0A1F9IJF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFCSPLOWO2_02_FULL_53_8|TrEMBL
MSLREELNSGRFVITAEICPPRGTDTAAFLEKARLLKGKIAAANVTDNQRAVMRLSSLAC
SVLLLREGIEPVFQMTCRDRNRIALQSDILGAWVLGIRNILALTGDHVSAGDHRGSKAVF
DLDSVQLVGLISTLNSGKNLNNVELRGKTDFFLGGVVAPEAAPWEPEEIKFEKKIMAGAR
FFQTQAIYDMERFKRFFDGAGNRGAKILGGILLLKSA
>A0A518UCM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denitratisoma sp. DHT3|TrEMBL
MSKPELSIEFFPPQTPEGAVKLREARARLAALNPAFFSVTFGAGGSTQERTLDAVLEIQR
EGHQAAPHLSCVGSTKGRIRDILGRYKTAGIRRIVALRGDLPSGMAHPGELRYANELVEF
IRQETGDWFQIEVAAYPEWHPQAKSAQEDMRNFKRKVEAGADAAITQFFYNADAYEHFVG
EARALGVAIPIVPGIMPIGSFSKLSRFADACGAEIPRWMRRKFEGYGDDAESIRAFGLDV
VTELCQRLLDRGAPGLHFYSLNQSALTTEIVRRLGL
>A0A5S4G2L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura geliboluensis|TrEMBL
MGVGLVGFEVVCEVEPPTRPDLRKVRHQIGVLSPVADSFLIPDNHIGRATVSSVAVAHEV
QAMGARGIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVYGDKPSAGGRTSELTVRAMME
EARAASEDAVFDGCGAFQVGVTSGLRRVPEWKRAADFTFVQVSYSVENLLRWRESAEIDG
PVYAGVMVLASAGMARNLAAAIPDIDIPGELVEAVERDRSAGVAAACEQVLAIRDSGAFD
GVHLVPVSRYREVAARLEGEL
>A0A318B588|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. D5|TrEMBL
MTLPPTRRVIGPVARAGERPVGAVRPRVSFEFFPPKTEKMEASLWEAITRLAPLDPAFVS
VTYGAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRAEVDEVIHDYWNIGVRHIVSL
RGDPPPGEGGIGGVYAPREDGYKNATELTAALRGIAPFEVLVGVYPEKHPESPSLDHDIE
VLKAKVDAGATLGISQFFFDIDAFLRFVDKARAAGITIPIVPGIMPVTNFNGLKKMSVAC
QTSVPSWLANLFDGLDEDPETRRLIACSVAAEMCAKLQEQGFNDFHFYTLNRADLVYAIC
RVLGVRETAPAPAAEAAA
>A0A7G6XNB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. INR7|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMADWVAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVEKAGCDTPIIPEVMPVVGIKQLDRLPQLSTAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A800N9L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus firmus|TrEMBL
MSFLNKLKNEIIIADGAMGTLLYSYGTDSCFEELNLSQSEQIQHIHEAYIGAGAELIQTN
TYAANYLKLQRYGLEDSVKEINSAAARIAKKAAAERAYVAGTIGGIRGFKPNMITLEEIK
RSFREQLYCLLLENVDGILLETYYDLEELETVLAIARKETDLPIIAQVSLQEAGVLQNQT
SIADALAKLEGIGADVVGINCRLGPHHMLKTLESVPLPKHAHLSAYPNASIPAYTDGKFH
YEGDAEYFRQSAIEFRNQGVRLLGGCCGTTPDHIKAFADVLKGLPPIEEKEIKAVNKVIV
SEKPESSRELPPLQDIVRERPSVIVELDPPRKLDTSRFFEGAKALKEAGIDSITLADNSL
ASPRVCNSALGYLVKQQTGLRPLVHVTCRDRNIIGLQSHLMGLHALGLSDILAVTGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSFSGKDLGQKAAFSVAGAFNPNVRSLEKAVG
RLEKKIEHGADYFISQPVFSEEKLLEVHEAVKDLKAPVYIGLMPLTGSRNAEFLHNEVPG
IKISDSIRSRMASLKDDPAQAGTEGIAIAKSLIDAAAELFNGIYLITPFMRYEMTVELSN
YARETTERLSRRKQHA
>A0A5N6S9S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus pseudotamarii|TrEMBL
MHIKEKLAQNEAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAADGGLRYAKDLVRYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGATF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYSAFIRRANWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDQLKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIRDLSHLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLVE
LNNRGILTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIESNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDNWYLVNIVNNDFHNTYDLFDLFKDLNVRDFDVEVTSDNADSK
SQENEAVEATAN
>A0A2S9QCV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labrys okinawensis|TrEMBL
MAGHALPSHGGIRVSFEFFPPKNAEMEASLWEAIERLAPLDPLFASVTYGAGGTTRERTH
GTVARMVQETDIRPAAHLTCVGATREAIDEVIRGYAEAGVRHIVALRGDPPAGVGARYEP
HPGGYASSADLVAGIKALGDFEVSVSAYPEKHPESPSLAFDIDILKAKVDAGATRAITQF
FFDNEHYLRFVDRVREAGIDIPIVPGIVPVQNFNQVRNFAERCGTDVPQRLADRFEGLDN
DVATRKLVAAAVAAEQVFDLVDRGVSDFHFYTMNKADLVYAICHLLGLRPKVEKAAA
>A0A369JH00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypsizygus marmoreus|TrEMBL
MKLTEKIKASWSPHPLYMFEFFPPRTDQGFENLIARISRLCALNPLAISVTWGAGGSTRE
RSLDLAGLTQTEYGVDTLLHLTCTNMELGMVEDVLRTAKERGIQNILALRGDPPRGEEEW
IAVDPRFKHATDLVKFIRSSPEFASHFCIGVAAYPDGHSESTLDEDAELAFLKDKVDAGA
DFIVTQLFYDVDRFLKWLKKVREKGITVPVIAGIMPIQTYGSFARLIKLCGIRVPQDIMD
DLAPISHDDQLVKDYGVKLAVDTIQRLTKESDVAAVHFYTLNLEKSVQRVLELLQWTGVP
APNHNKLIAETPGNTIHPPPETDKSNFLVTPSSATNSATLGLANIPPTEEAGRGELNNAA
TWDDFPNGRFGDFKSPAFGNQDPWGGPAIVRSDVLSWGHPKSLEDLTQLFLDHLHSKIST
TPFSPTPLSPESLMILTHLERLTKRGWWTVGSQPAVDGVSSADEVLGWGPRAGYVFQKGF
VEFFCDKDDIDAIERRVEEKGRGWVHWFAGNFDGECRGNVPEDGRNAVTWGVFPGQEIAQ
TTIIEKESFLSWKEEAFSIWSDWASFYRPGSEERQVLEKVRDERWLVSIVHHDYKDPEAL
WTFLFGEET
>V8QZE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas moraviensis R28-S|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETADHFHIEVAAYPEMHPQARNYEDDLANFVRKAKAGADSAITQYFFNADSYFY
FVDRLQALGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTRSIQSFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A4Y8VS65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella hominis|TrEMBL
MNITEFLNNGAQEKGFSFEVLPPLKGNGTAALFRTIDALKEFNPRFINITTHHSEFVYKE
LDNGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHVICSGASKEDIEYELLDLQFLGISN
LLVLRGDKAKDDRQFTPTANGHMHATDLLKQVNQFNDGFFMDGTPIKHPGEKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNQKFYDFVEKARKMGITIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDDDAKELGIEWTTAQVKDLFEHGYNNVH
FFTVSAVESVKQIAKTLF
>Q7VE38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)|TrEMBL
MNSILQQSLEASEITITAEVMPPRGGDPSKTIAAAKSLSGFVHAINVTDGSRAIMKMHSL
AVCKLLLESNIEPILQIACRDKNRIALQAEILGAHALGIKNVLCLTGDPVRVGDQPNARP
VHDYESVQLLKQITSLNLGEDPVSGLLPNGPTKLFLGTAADPNSTNFKSLRKRLERKKNA
GARFIQTQMVMDPKTLEKFCKEIAEPLELPVLAGVFLLKSAKNAHFINKVVPGASIPMSI
LNRLEQAKEQDLEGITIAAEQARSFVGIAKGIHIMAIKAEHNIPAILNQAKISLPSQ
>H1RZD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus basilensis OR16|TrEMBL
MQDRYFSFEFFPPKTAEGAEKLRNTRAQLAPLQPKFISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRDILKTYRQGGIRHIVALRGDMPSGMGEIGEFRYANELVAF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVKAGADSAITQYFFNADAYFRFVD
DVRAMGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNTASATKAIWQRLKL
>A0A4S0Z800|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.163.01.1.1|TrEMBL
MPAGLSLRADAFINAFSLEVSAKAMPALRAEADRIPRGTVISIPYLASEDDDARLAAART
VRALGFEPMPHLSARRIGSAAALARFLERAVGEAGVARCLLIAGDLATPAGPFADSASII
QTGLLEHSGIKVVGIGGHPEGHPVMSSDERWQALERKCQDIEARGMAPLVVTQFAFDADT
VLAWLDGLRARGISVPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGISIGRLIGTA
GPEVFVDRLVRGLTSAHGQVSPHFFPFGGIAPSLEWMVQYRRRISGTGG
>A0A193G4P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella bronchialis|TrEMBL
MTDTNTPAYSLEFFPPRDIAAQERLLRAAKQMLAIHPRYVSVTFGAGGSTREGTAGTVRM
LRNLGVDAAPHLSCMGATRADLRAILASYREEGVRQVVALRGDLPSGMGGDAGELKYARD
LVAFIREETGDWFHIEVAAYPEMHPQADNPTSDLDHFVEKVRAGANSAITQYFFNPDAYF
DFLERVAAKGVSVPIVPGIMPITNHTQLARFSQMCGAEIPRWIRLRLAEFGDDKASIRAF
GVDVVTDLCRKLLDGGAPGLHFYTLNSAEAPMAIWKNLTAV
>A0A3D6EP83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagales bacterium|TrEMBL
MKVIDHLKRANGKTLFSLEILPPLKGENIKSLFSNMDPLMEFKPPFIDVTYHREEYVFKK
KEGGLLEKITTRKRPGTVGICAAIQNHYKVDTVPHIICGGFTREETENALIDLNFLGVDN
VLVLQGDAIKTESKFIAEKDGFGYASELLEHVVNMNKGQYLDEELHDPSPTNFCIGVAGY
PEKHFNAPNLKTDLKYLKNKVDKGAEYIVTQMFFDNKKYFEFVDKCREAGITVPIIPGIK
PLTTKSQLTILPQIFHIDLPEELSDEAEKCKDNASVKQVGIEWTIQQSKELIAKGAPTIH
FYSMGKSDPIYRIAKELF
>A0A161WZ37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulosimicrobium sp. I38E|TrEMBL
MSVADAVGQAHGGAARPTVSFELMPPRRPDAAPKFWETARRLVATHPDFVSVTYGAAGTD
RATARQVVGRLLQGTPVLPIAHLTCVGASREDVEEVISDFLDEGVRSFLALRGDPPRDQP
DWQPAPDGVRSSTELVALLREVEASRCASDPAAALRGAARPLTIAVATFCDGNPAAGTTR
AQEVRRLWQKQQAGASFAITQLFYDASSYTDFVAEARAAGVTIPILAGLLPTTEPARLRR
VEELTGVRAPQHLLDALDALPDPEAQHAYGIAYTVDLAQRVLDAGTPGLHVYTFNKHRAA
LDLLEGVHLGGGSAGTGGSTSAAAAPLVPDLASGPWVTGTSLPTTSAATHGTPV
>A0A4R6GPK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas ventosae|TrEMBL
MSTQEHPLGISFEFFPPNTDAGREKLVGVRDALASRAPRFFSVTYGAGGSTQDRTLNTVR
MVRESGFTTAPHLSCIGSDKGALRELLSRYREEGIDSLVALRGDLPSGMGGGGVGQLRYA
NELVEFIREETGDHFEIAVAAYPESHPQAANLEQDLSNFARKMKAGADIAITQYFFSAEA
YFHFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIG
AFGEEVVSRLCQRLLDGGAPGLHFYTLNQAAPCLRILDNISD
>R6GMK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum CAG:234|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIANTIH
GEYGIPAVAHLTALYSDEAKIDEALDMFEAAGVSAVLALRGDYIDGEEPVGRFNHASDLA
AYIHDRKPDLNVFGACYPEGHYSAASLDEDIGNLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGAKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGII
YASDQIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFTVE
>A0A1L5LTM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus xylanexedens|TrEMBL
MKADLRKVMQERVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQISALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFAELGARIIGGCCGTTPDHITAMKEALADYVPSPILEPDPSE
SKPRIVLHEHVDERSGRGGQPTIVDLVKHRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALSINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLEKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A850UJG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloropsis hardwickii|TrEMBL
MVNETQHACSASSSSRSDGGSSSGSESSRDNSRCSTPILDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLRKAKRLGLKNIMALRGDPAGAEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEADSYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7C3EAM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema caldarium|TrEMBL
MNISLELVPRDEQSISEGLSVVSRYSDISLINIPDLLRFPIRSWEACAIIPPHYRSIPHL
RAIDFNLDEPFTLGEYFKNHHIDRVLVVAGDPPQDMKHRVFPTHTTDFIKKLKTELPELT
IYAAFDPYRSNIRYELDYLKAKEDSGAEGFMSQPFFDVRLLEIYAEYLEGRTVFWGVSPV
LSEKSRNYWEARNRAIFPRSFRPDLHWNISFGRQVLQFCKTNHFDLYLMPIRVDLDTYLQ
GLFS
>A0A7X6UY93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp|TrEMBL
MNNFSQKIALELVPNSFETLLDEAQISQKVTQKVQCINIPEMMSKEIKAHHAADLFLKNG
FDAIPHFRTRERTIDELAELISPLIALGLNKVLLITGDPPKDNPNEAAKLTPVQAIPQLK
ERFPQLKIYVGLDPYRQSFITEFKYCQEKLAAGADGFFSQPFFSPHLLSLWLEQLHNTEF
WVGLSPVTTPSFKKYWENTNHVVFPPEFSIDLKENCLEQQKLMKLAAEAGQHIYLMPITV
TVEEYLKQLL
>A0A6L7Q8Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Holophagales bacterium|TrEMBL
MRSAIAGGRPFYSFEYFPPKTEAGIENLYARIERMGRLEPAFVDVTWGAGGSTAELTFEL
ANTIENVLGLETMMHLTCTNMPRRRIAAVLDDCRARGIGNILALRGDPPRGRGAWSPIAD
GFSHASDLVRFIREEHGDHFGICVGGYPEGHPEAPSRGRDLDHLAAKVETGADFVITQMF
YEPELYFRFLEDCRDRGIDCPIVPGLAPINGYQSFLRITGFGASAPPEIVSEIEARRFHD
ASVREYGQDLLTDICRRLLDGGAPGLHFYTLNLERSVQVILDRLGIVPERVERVLPWRSA
TAVGRPKEDVRPIFWANRPKSYLARTQDWDEFPNGRWGDAGSPAFGDLGDHHLAFRPIKP
DVARERWGRELRSIDQVREVFAGFCRGDVDGIPWYDWPLDLESEPLRNALVRLNLAGLLT
INSQPRVNGAPSDDPAVGWGGAGGRVYQKAYLEFFVAPEQVSPLLAALDRKPSLTYHAID
RSGTAYSNCDTVNAVTWGVFPGEEVRQPTIVDPRSFEVWKDEAFDLWLSSWAAVYEEGSE
SRRLLQHIHDTYFLVNVVDNDYIDGDLLAYLIEAAQADEPPSMTIVAPVT
>A0A2T4JN25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeovulum veldkampii DSM 11550|TrEMBL
MTTPRISFEFFPPQTLDASFRLWETVQVLAPLKPSFVSVTYGAGGTTRQLTHEAVTTIGK
NYGLNVAAHLTCVDATRAETMEIVNAYAEAGVREIVALRGDAPKGADRFTPHPEGFASSV
ELIAALAADGRFTIRCGAYPEPHPDAADPLADVRWLKRKIDAGATSAITQFFFEADTFFR
FRDACVKEGITAPIIPGILPIQSWEGAKRFAARCGTRVPPRLDEAFATAKRDGREDLLSL
TLCTALCDKLVQGGVEDLHFYTLNRPGLTRDVCHALGVTPDVGLEQVA
>A0A6L8WBK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sneathiella litorea|TrEMBL
MSTPAPHDISSPLPPLPGHTSRGRLERVLRAGEFAVTAELNPPDSADPNEVFDRGAVFDG
WVDGINATDGSGANCHMSSVGICALLTRVGYSPIMQISCRDHNRIAIQGNVLGAAAMGVN
NILCLTGDGVQAGDQPGAKPVFDLDCMSLLRTIRLMRDEGRFLSGRKITSPPQVFLGAAI
NPFAPPYDFRPLRLAKKIEAGAQFVQSQYCFDIPMLERYMMQVRDLGLDEQCYILIGVGP
LASARAAKWIRSNVPGIHIPDAIIDRLEGAEDQKLEGKKICIEMLQQVREMKGVSGAHVM
AYRQEELVAEIVHESGILKGRRPWTRENNPDYEAVAEAIETVKDQSEHPIDPEEAVAAAF
EEH
>A0A1H7D649|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. AP50|TrEMBL
MSLPSIHPNWDLPPKGMTDGYSLEMTAKDMEALVEAAPAMAAETPVAVTFLPGESLEARI
AATKAVRDLGFEPMPHFSARRLESGDDFETYLAAVVREAGVRRCFVIAGDPAEAAGPYSD
SMALIRTGAFERAGIKAIGIGGHPEGHPNMSREQTFEVLIDKCAEIASRNMAPLIVTQFG
FDAAPILQWLVELRARGIDAPVRIGVPGPAGIKTLMRFAARCGVGASTSVLTKYGISITK
LIGTAGPDKLVDALGKGLAAQHGKVRLHFYPFGGLTRTVEWINDYTARP
>A0A5B1AML3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MIIKRIMHKLPDISAASIIPASIEASPAQVLGASDLAGLFPQGVRVYLTDTGAASQERLV
DAAGHLRDLGYEPVPHLAARRIASRTGFEEQVRRLAGEAGVTDVLVVGGGVDRPAGPFAS
SMDMLSSGIFDRCGIRQIAIAGHPEGSPDFNDDTAMAALRLKRDFAERSDAAMRIVTQFG
FDPARFIAWAEGLKASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESIVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGGADRSAS
QDSIAG
>A0A166JSG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibularhizoctonia sp. CBS 109695|TrEMBL
MKLSDKIKAYEPTRPFYTFEFFPPRTDQGFENLVSRIQRLALLDPLAISITWGAGGSTKE
RSLELAGLTQAEYGIDTVLHLTCTNMVKGLVDNALREAKERGIETILALRGDPPRGEEAW
TPVDPAFTHAVDLVKYIRSSPEFSSYFCIGVAAYPDGHPDHETDEAGEFKYLQEKVEAGA
DVIFTQLFYDVDGFLAWVKKVRAKGITVPIVPGIMPIQTYSSFQRLIKLCGCKVPPEVTA
ALEPIHHDDQKVKDYGIALAVDTIRRITAESDIRGVNFCTLNLEKSVQLVLENLHWTGGS
PHDTAPSPLLLPTQHNYDLLTTPNLATLSAKSGLANLPPTDSEAGRGELNNAASWDDFPN
GRFGDYKSPAFGNQGLWGGVGITRSDAFAQWGHPKTLDDLTSLFLRHLHSEIATTPFSSE
PLSPESLTILAHLEKLTHKGWWTVCSQPAVDGARSSDEVVGWGPRGGYVYQKAFVEFFAE
EADVEHIEKKVRESGKGWVDFFAGNLQGECRTNMPEDGRNAVTWGVFTGQEIAQSTIIER
ESFLSWKEEAFSIWTEWASFYRPGSKERNLLDGVAQKRWLISIVHHDFKEPEGLWTFLF
>A0A411T1I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes faecalis|TrEMBL
MSKKQTLSLEFFPPRDSAAQEKLVRTAKTLMGLNPAYVSMTFGAGGSTRAGTVDAVALLQ
NLGLDVAPHLSCIGTAPAQLGEMLDTYRDQGIRRIVALRGDLPSGMGGDTGELRYASDLV
SFIREHYGEHFHIEVAAYPEMHPQATSLEEDLGHFVNKVKAGAHGAITQYFFNPDAYFSF
VERAQAQGVTIPITPGIMPITNSSQLLRFSTMCGAEVPRWIRLRLADFGDDRASIRAFGI
DVVARLCQDLLDGGAPGIHMYTLNGADASMAILPNLTWR
>A0A1P8R7K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. 1513|TrEMBL
MSVQEHPLGISFEFFPPNTEAGREKLVGVRDALAERGPRFFSVTYGAGGSTQARTTRTVK
MIGESGINTAPHLSCIGSDKGELRELLTQYREDGINSLVALRGDLPSGMGGIGELRYANE
LVEFIRAETGDHFEIAVAAYPECHPQAPSFEHDLQNFARKVQAGANLAITQYFFSAEAYF
HFADRARALGVEAPIVPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIQAF
GEEVISRLCQRLLDGGAPGLHFYTLNQANASLRVLDNLA
>A0A484HAY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|invertebrate metagenome|TrEMBL
MKAYESADAVQNGNLSLLALPGPISVSFEFFPPRTAQMVGILWECIRRLEPLAPRFVSVT
YGASGSTRERTHDTVVRIARETSLKPAAHLTCVGASRAEVDHIAHRYWEAGIRHIVALRG
DPPERQNHYVPHADGYAYAVNLVRGLKTVADFEITVAAYPEAHPEAPSAAFDLDNLKRKI
DAGASRAITQYFFDIDVYRRFMDKVRAAGITVPVIPGILPVTNVATMLRFSQACGTAVPS
WVHALFDGLDADPDTRRLVAAVLAAEQCRALVTDGVTDFHFYTLNRADLVFAICHILGVR
QQWGSKVAADRT
>A0A178K5Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. CCUG 49591|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A5J0GM80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Ajiobo|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1R1B8A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus lautus|TrEMBL
MKPNLRQAWENQVLVGDGAMGTYLYQKGFPVGISYEELNLTSPEVIGNVHRQYAEAGAQV
IETNTFSANYDKLSKYGLEAKVGEINRAGVRIAREAAGDHGYVVGAVGSIRAGKRSNIST
SELKRYFEEQLSVLISEGVDGILLETFYDVDEIQLALAQARMLSDLPVICQFAVEDIART
LDGFTMPDAYRILSQEGADVIGFNCRTGPNGIMRALETLNGIMNLPASVYPNAGIADYVD
GEYLYGASPEYFGKTALEFAKRGARIVGGCCGTTPEHIAEISSALSDYVPAPLPAVDEAE
VNRIVIHETAQEQFYERIGEPTIVDIVKERHTVIVELDPPRDLDITKFMKGAEALKKAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVVGAAFNP
NVRHLDKAVARLEKKIASGADYVMTQPVYDPELMVRLREATAHLDIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAMGVKIGKELLDVATEHFNGIYLMTPFMFY
EMSVQLMEYVWEKSGRRLTPLFH
>T0HWV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. UNSWDHB|TrEMBL
MFISELFQQKKVVSFEIFPPKLTSSIEVIYDTIDALAPLRPDFISVTYGAGGSTSKTTAE
IASIVENKYNINSLAHLTCITSSKEQIEGTLTQLADSNVSNILALRGDIPKGSEETGRAR
DFQYASDLVAYIQDKHSFCLGGACYPEGHPECPDKDQDIENLRRKVDAGVGFLVTQLFYD
NDAFFRFQEKVANLNINVPILAGIMPITNRVQIERILALSNARMPQKLIKILDKFEHNME
ALKDAGIAYATKQIVELLANDIDGVHIYTMNKPQIAKDLVRNLDSLFYAVNSQETRKEGN
LA
>A0A2M7D537|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp. CG02_land_8_20_14_3_00_36_67|TrEMBL
MFNKLLDKLKHGTFISLETTPGHSPLFSPTIEKIASLELDKYVDAFSTTDNPLAKLKYNS
LFAAKMLQDRFNKPVIATMSMRDRNKIALQSDLLGANEVDIRTILALTGDPATISDQPHT
KGVFEADSSMLLDIIACFNSGIDYAGKPLTHKPQEIFPFAVVNAYSKNPKTLQKKMQKKI
KHGACGIITQPVYDLENAKRLLELKEAANKECSSEGREAELILGIFPITKLRTAQFLATH
VPGINVPNSWIEALRSANEKGSEEEYKVGLELSKNLFDEIKDLHPKIHLMTANQFQIAKD
ILV
>A0A838HNA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euzebyaceae bacterium|TrEMBL
MTDIATAKLVASLEHPRFEVIPAKGVEEQIAHLPAGATVTITSSPGKGIDATLDLAARLA
AEGFAVVPHIAARLVAGVGHLEAVLRRFDELRLRDMFVVAGDAAQPAGPFEGAAALLAEM
ARLGHGLDDVGITGYPESHAFISDETTIQTMFDKAPYATYIVSQICYDPAVTAAWVGAVR
DRGVDLPIHIGIPGVVDRARLARISFKVGLGDSARFLRKQGGVVTKLLAGYTPDDLVERL
GPMVADETQRISGWHLFTFNEVERTERWRRQLLDRLAS
>A0A392QI06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trifolium medium|TrEMBL
MTGFCKTKIPAEVMAALEPIKDNEEAVKAYGIHLGTEMCKKIMAHGIKTVHLYTLNMEKS
ALAILM
>A0A0A6Y0I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 329 str. F0087|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKIEAGADYVVTQMFFDNQKYFEFVDKAREAGINVPIIPGIKP
IAVKKHLNLLSQAFKIDFPQELVEAVEACKHNADVKQIGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A420XPJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Motilibacter peucedani|TrEMBL
MPVSSPTAPRTAQRPGRVGALLSSGTPSFSFEFFPPKTDEGERQLFRAVRELESLSPTFV
SVTYGAGGSTRDRTVRITRRIAEETTLLPVGHLTCVGSSRDELRSVIGQYADAGVRNVLA
LRGDPPSGVGTEWRPHPEGLSYAVELVELVRSLGDFSVGVAAFPEKHPEAPDLDADASRL
ADKAAAGAEFAVTQFFFQSADYFRLVERLDALGCRMPVVPGLMPVTNVAQIERMVALSGA
AFPARLAERLHAVDGDPEAVRRVGVEIVVELGQELLDGGAPGLHFYTLNRSTATREAYAA
LGLGSR
>A0A161Y5L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Daucus carota subsp. sativus|TrEMBL
MKVIDKIREISSSNGEDNKVVFSFEFFPPKTEEGVENLFERMERMVSHNPTFCDITWGAG
GSTADLTLEIANRMQNMVCVETMMHLTCTNMPVDKIDHALDSIKSNGIQNVLALRGDPPH
GQDKFVQIQGGFSCALDLYGDYFGITVAGYPEAHPDVIQSNGVATLESYQNDLAYLKRKV
DAGADVIVTQLFYDTDIFLKFVNDCRQIGITIPIVPGIMPINNYKGFLRMTGFCKTKIPA
DVTAALESIKDNEEAVRAYGIHLGTEMCKRIMASGIKTLHLYTLNMEKSALAILMNLGLI
EESKISRTLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWEQYPHGRWGDSRNASYS
ALADHQFMKPRSRDKKLHEEWVVPLTKVEDINEIFNNYCLGKLRSCPWSELDGLQPETKI
INEQLGNINLKGFLTINSQPAVNGAKSDSPSIGWGGPGGYIYQKAYVEFFCSTDKLNALV
EKCKGFSSLTYMAVNQEGSWISNIKQTDVNAVTWGVFPAKEVIQPTVVDPSSFLVWKDEA
FEVWSKGWAQLYSEDDASKKLLEEVKSSYYLVSLVDNDYIHSDLFAVFKDL
>A0A1F9PN95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca sp. RBG_16_60_12|TrEMBL
MPLREKLTSGEFVILAEMEPPKGTDVSDMVAAATGVKRMVDAFVVPEMNNAVMRLSSLGG
ALLLQTKGLETVMQVCCRDRNRLALQGDLLAAQALGVPNVMAVTGDEITHGDHHQAKPVH
DLELLELLTAIQTLQTGRDLAGVDLKGAPNFLVGATVKVTGEAHALKQELADLDHKIAAG
ARFFTTQPVFDVEVLEKFRQQVGKRQAAIIPTVMLLKSVGMARYINAHMEMKIPEAFVTR
IQKSSD
>A0A2A9E976|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sanguibacter antarcticus|TrEMBL
MTASRTAPTTLQRPAARQRPTVSFELMPPRNPDAAPKFWATAERLVAARPDFISVTYGAA
GTDRNTARTVVSRLIQHTPVLPIAHLTCVGASRNNVAEVIDEFLAEGVRSFLALRGDPPA
DQPDWEPHPEGVHSSDELVALLREVEAGRCASNPSTALRSAAHPLTIAVATFLDGNHAAG
TTRSQEVARLLQKQEAGADFAMTQLFYQPESYVDFVAEARDAGVTLPILAGILPMTDPAR
LARVEALTGVPAPSALVRDLEAVSDPAARHRLGIRASVELAGAVLAAGAPGLHIYTFNKH
EAALDLLEGVHLGGGQTTGVLPGAGPDLASGPWVGASPHTTPLIAATH
>A0A246FGS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas nitroreducens|TrEMBL
MSQKERRFSFEFFPAKTEAGHEKLLATARQLAAKKPDFFSCTYGAGGSTRDRTLTTVLQL
DGEVQVPTAPHLSCVGDTKGELRALLAHYKDAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRNETGDHFHIEVAAYPEVHPQARNFEDDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAEKLGVSIPVVPGIMPITNYTKLARFSDACGAEIPRWVRKQLEAYGDDIASIQAF
GEQVITDMCERLLEGGAPGLHFYTLNQAEPSLALWNNLKLPR
>A0A561VFU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora palomenae|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTAEGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVR
GDPPGDPGGEWVRHPEGVLYAEELVRLVRDAGDFSVGVAAFPYKHPRSTDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFERVADDPEAVRRLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWRSLQ
AGARV
>A0A431NFL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MATGPAAQCPKRMRFGPCGGVRADLSCEVGPVRCPFGTLDDPVPWNGPEPPRRPEPPRRP
EPALLAAAPVVLTDLTTPPFDRHGLARVVTTLAGTCDGLLVGEHHNRPDFPPTQMTALVR
EAGGAPVVTLTCRDRNRVVLDQELAGLAEEGPAAVFCATGDARAAGMRPEVTQVFDLDGT
TLAAHAAAAGLTAGVPESPGAPPLRLRPGRLAQKQRAGAQFAVLNHVAGPARLAVFADRA
RTAGATLPLVAGVAVYTDERSARVLAAFPGLHLDPDRIGTVLGAPDPVEAGIAEAVEQAR
ALLAVDGVVGVNLSGLASAKGPAEGAAVKAAVGRALKDAA
>A0A6G5QJG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter mucosalis CCUG 21559|TrEMBL
MLKGNLKNNKAGILLYGLTPPKSEFDEQKLREISSRWTERINSVNADGLVLYEIQDESAR
MGERTFEFSDTLSPNNYYNDYLNVKTPSIFYNVANKYDEQKFREILAHQSANLSVFVGAA
SSKIEPKMSLNRAYEIARDEFKNLCVGGICIAERHAKKGDEEQRMAHKVSLGAKFFISQA
VFDLPLAKELLNAVARANLNVPIIFTFTTCGTPKTLEFIKWLGINVPQNVEERLLKSSDI
LAESSKICVENFAQLYLLGQNLGVSVGANIESVMAKRAEIEASLSLVKEFRGVL
>A0A6P1T055|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium 9Alg 56|TrEMBL
MTTFEQPDTSRRSLSFEFFPPQTTEATLRLWRSVERLAPLQPQFVSVTYGAGGTTRDRTK
AAIRTIRDRAHLNVAGHLTCVGATREETLEVASEYSAIGVNRIVALRGDPPKGVDNFTPH
PDGFSGSVELVGALVERGYDVAVGAYPEPHPEARTADDDINQLKAKVDAGATSAITQFFF
DTELFLRFRDRCVAAGIDVPIHPGILPVEDFTRMKRFAGACGTSVPTWMDDAFGRAENEA
SATLLATAIATDHCDILMREGCDHLHFYTLNKPDLTYDICRALGFATADLMMASGQGAA
>A0A8I1PZS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MTSAVDSGATTPISFEIYPPRSDEGLPALYTTIGALAAVRPQFISVTFGAGGSTRGRSLD
VLTHILHATDVPPLAHLTCVGSSYAEANAIIREFLDAGITRFLALRGDPPAGTSEDDVFL
GDLESAAQLVQLIGRVQAERAPYAEELVPGVPGAARVGRRERVQISVAAFPNGHPRSRHA
GEDIDALLAKQAAGAEAAITQLFFHADEYLGFVDRARSAGVTIPILPGIMPITTPGRLRR
VLELTGDPSPAALAQALDAADSPAAQRAVGIAHAADLARQVRAGGAPGVHLYAFNNHETV
LAVLHEAGLRTTASHDPYDHAI
>A0A7X9QSD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. DNRA2|TrEMBL
MSFLSKLENQILIGDGAMGTLLFSYGKDSCLEELNLSNPEQIHSIHRAYLNAGADIIQTN
TYAANHLKLARYGLEDSVKEINSAAVQIAKKAAQGNSYVIGTIGGNRGIKPKSINLEEIT
ASFREQLFALLVEGVDGIILETYYDLEEMEAVLAIARRDTELPIIAQLSMQEVGFMQDHT
PIAEALLRLENLGADIVGLNCRLGPHHMLKALEQVPLPKHSFLSAYPNASLPTFTDGEFH
YEGNADYFRNSAMAFRDQGVRLLGGCCGTTPDHIRAFAEELRNVQPITEKVLKEDPAKIV
VKVVETKRDIPPLHEIVKERPSILVELDPPRKLDTTKFFEGAKALKEIGIDAVTLADNSL
ASPRISNSAIGHLVKTQLGLRPLIHITCRDRNIIGLQSHLMGLATLGLNDVLAITGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSVSGKDLGQKTSFSVASAFNPNVRSLEKAVV
RMEKKIAHGADYFITQPVFSEEKLIEVYEATRHIEAPIYIGLMPLTSYKNMEFLHHEVPG
IKISDTIRESIARYKDNPVLAAQEGLVITKSLIDTALELFNGIYLITPFLRYELTVELAD
YTNKRIANLARGKENVQSIIQ
>A0A6I5N4Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rochei|TrEMBL
MALGTASTRTDRARTVRDILAAGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVELIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEIMPVTSVKMLERLPKLSNASF
PAELKERILAAKDDPAAVRSIGIDFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A0M1J058|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. L74|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKDIIGE
YNYAFKLIEKIKENNNFGISGACYPEGHIECKSLDQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQQKSINVPIQAGIMPVINKKQIERIVKISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A4V3CA91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2571|TrEMBL
MFELICEVEPPTRPDLKKVRHQIGVMSPIADAFLIPDNHIGRATVSSVAVANEVQLMGAQ
GIACLNSRDRNLLGFRRDLLTAAAYGVQRFLFVHGDDPAEGARTSQLTVRRMIEQTRETT
YPGCDPFKVGAATRLRPVPKWKAEADFLYVQVSYDLDELLRWRESVELDIPVYAGVMVLA
SAQMARNLAGLPQLNIPAELIEAVERDRDAGVDHACEQILKIRDSGAFEGVHLIPVSRYR
QVAARLEREL
>A0A4Q2A1R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusibacter sp. A1|TrEMBL
MKISKILEEKPFSFSFEVFPPNDDTKLPKLLSTTNKLHSLDPDFISVTYGALGGTKNNTF
SIAKNIKDIQNMNAVTHLTCVNMTKAEAAQTLHSMRYFGIENILALRGDKGETDVPGDFR
YASDLIRFIKETQPDVFSIGGACYPEGHIEARNRTEDILNLKMKCDSGLDYLLTQMFFDN
EIFYDFMDRLTLAGIHTPVIAGVMPVLNAKQILKICKFSGATLPKKFVRIIEKFEHNPEA
LREAGIAYASEQIIDLISWGVRGVHLYTMNSFKTADQICGNIEFVRSSR
>A0A1H5W1U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera chlorobenzoica|TrEMBL
MSTEISIEFFPPTTAEGADKLRTTCARLAALKPAFFSVTYGAGGSTRERSFATVRDITAA
GFEAAPHLSCIGSSRDSIRAILQDYADAGIGRIVALRGDLPSGVQDPGEFRYANELVEFI
RAETGGRFRIEVAAYPEWHPQAKSPKDDLLAFKRKVAAGADAAITQYFYNLDAYLHFVDA
ARKMGIDIPIVPGIMPVGSFSKLARFSDACGAEIPRWMRKTFESYGDDAESVRAFGLDVV
TRLCERLIAEGAPGLHFYSMNMAGPTTEICRRLGLAA
>A0A519GNP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
YEAGAEFGVTEMVLRASDYFGLVDRCRAAGIDMPIIPGIMPILAIGSMKKMVELSGREMP
TEVLERIEPLADSPDEVRAEGIRIATELCDDLLAGGAPGLHFYTLNRSKATREIYTALAV
NA
>A0A4R3BAK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. BK205|TrEMBL
MLATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVKETEQ
IVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWLAHPQGL
TYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDTDVSHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVDAAGCPTPVIPEIMPVTSVRMLERLPQLSNAIIPSALKERILTAQDDPTAV
RSIGIEFATEFCARLLSEGVPGLHFITLNNSTASLEIYENLGLHHRPQA
>T1AD17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
VHVSCRDRNLLGLRQQVIGAAALGAAGVLVVRGDRKEGMVDSRISVVDVLADIPDWALPQ
ELLRGAVVNPFADRPRELRLLARKVGAGIDFLQTQMIFDLDAFDSFLEDARDVRPPGGGG
FCQRGGHPL
>A0A7C9HBE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sediminimonas qiaohouensis|TrEMBL
MTGQTPDHQIAVSFELFPPKTEAGMKTLARTVDHLEAAAPEYFSVTYGAGGSTRDRTAKV
VDMVGGRTGLPVAHHLTCVGASRAQIDEQAKELWASGIRKIVALRGDLPEGESLAEDGYH
DAAELVAGLRNVADFDISVAAYPEVHPEAASAQSDLDHLKRKLDAGASRAITQYAFDTDT
VLRFIDRARDAGITAPIVPGIMPVANFASLKRFSQGCGASIPDWMEEMFAGLDETPEMRA
MVATSVATQQCQRLMAAGVDAFHIYTLNKPDVSLAICRALGLPVRAETECAA
>A0A1U6JL11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium chauvoei JF4335|TrEMBL
MSITELFNKKKVVFSFEIFPPKPTSDIKTIYSTLEELKDLNPDFISVTYGAGGNLVENRT
RELSALVKNKYGIETLAHLTCIGSTKKEIDFMLNDLSEIGVTNILALRWDIPINKEIKGE
FNYAKDLIEYIKKSRNEFNISGACYPEGHQDYKDVNREIMYLKVKEQEGANHFISQLFFD
NNYFYDFLDKKEKNNIKSPIQAGIMPVVNTRQIQRIVSLCGATLPKKFLKIIDKYEHDKV
ALRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYIARRINDNIKTILRYVNDDKLSKGSI
VI
>A0A0J7JE73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter subterrani|TrEMBL
MQSQKQFRRRFSFEFFPPKTDQGKEKLQNVRNRLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTREGISELLDVYKENGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLQNFARKVKAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSESIRK
FGEEVVTDMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISEREKIAF
>A0A1Q7QAB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_1_40CM_2_65_8|TrEMBL
MHIAEMLDRGRPTVSFEFMAPRDENEVQVLEKTVAALAGHAPDWVSVTYRLRTGQETLEL
VTRIKRQYHIEAMAHLTCANTRDATRRILNWMEREGIANVLALRGDPPGPGQPFQPADAG
LTHGSDLVAFVRGNGYRLGIGAACSAEKHPESPDLEHEFHYMRLKVEAGADFLITQLFFD
NRFYFDLVARARTAGIKVPIVPGLMPLPSRRSLAFVTEMSGASVPEPLQRAIDAQPDDEG
IRKLGVEHCIRQCVELLEAGVPGLHFYTFNRARAPIEILGALRGQQLLAS
>A0A1V5KEA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin467|TrEMBL
MRVIDIIRSDRVTVSCELFPPKIGQPLHDIRRVVREIAQLQPSFISVTCGAGGSTGDHTV
EVAREVQVENGVTALAHMTCLSTARAEILTTLEKLREYGVENILAIRGDLPENRESLRMD
YAHASDLIGEIRRFGGFSVGGACYPEGHPESESKRADLDGIRRKVDAGCEFLTTQMFFDN
NILYNFLFRLLKHGIQVPVIAGIMPVTREKQVKRIFQLSGTTVPPRFRAIVDRFSDNPAA
MKQAGIAYATEQIIDLIANGVSHVHIYTMNQPDIAGSIMLNLSEIFR
>A0A0Q7L0J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. Root473|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPQFCSVTYGAGGSTHQGTFGAVQEILAE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVKAGADSAITQYFFSAEAYFRFVDD
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVV
TDLCARLQEGGAPAIHFYTMNQSAATLAILERLD
>E6Q5L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MDIAGQLASRRPFFSFEFFPPKDDAGRAALFATIASLEALGPAFVSITYGAGGSTRARTV
ELAKQIAERTGITVLAHVTAYGQSRAELRALFDELSRAGIRNVLALRGDAPRSGEANAGE
FPYASDLISYLARSYDFCIGAACYPEVHIEAASPEDDLAHLGEKVASGATFLITQLFFDN
DKYFSFVERARAAGIRVPILPGIMPITNYDQIARFTKMCGATFPPKLIAELEKQREHPKA
IEDLGVAYAAVQAMELLRGGAPGVHFYTLNKSPAARAIGSALLAASAWRPVFK
>A0A1J5PN50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MPVENPTISFEFFPPKDELGEMQLWQAIDALHSINPDFVSVTYGAGGSTRDRTVRIACEI
YERAGFRTIAHLTCVGSTREELKEILLHYKESGISDVLALRGDPVDGPTAPWTATVGGLD
HAEQLVELASEVGDFTIGVAAFPDIHPASNGNFEQDIEVLLRKERAGATFAITQFVFDSQ
SYARLVETLKERGSALTIYPGIMPVTNHRQIKRMIELSGGHMPAKILEKFDRFQDDPESV
KSLGIEVATQICEEVYLTGAEGFHFYTLNSATATAQVIGNLSMYAR
>A0A252B4C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter sp. DsW_54|TrEMBL
MSLNRLCVELIPRSAESLEQDVKTVQTVFPAADTLNVPDLMRFPLRSWDAAAQLRPVFPR
VIPHIRAIDIAPHAPLPGAEQDGLEEILVVHGDPPADLSMRTYPNSTESIIRRYRKEAPH
LNVYAAFDPYRRAPWKELEDVARKKEAGACGFFTQPVFDYKLFDLCREWLQGENVFWGLS
PVIGPRSRSYWETTNHIVFPKDFSTTLESNIAFAQTVLRELGQDKGSAYLMPVRVKLEHY
LPALLDAVA
>A0A1F4AP38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_65_20|TrEMBL
MESQKKHPRTFSFEFFPPKTPEGVQRLSTTWRQLAQLKPRFFSVTYGAGGSTRDRTLATV
LEIKQAGFDAAPHISCIGSTLADIDETLDLYRSKGIRHIVALRGDLPSGAASAGELRHAN
ELVQLIRERSGDHFHIEVACYPEFHPQARSAQEDVRNFKRKVDAGANSAITQYFFNADSY
FRFVDDCEAIGIGIPIVPGIMPIGNFSQLARFSDTCGADIPRWLRLKLAGFGDDVASIRS
FGLDVVTDLCDRLLSAGAPGLHFYTMNQAGPTSTIWQRLGL
>A0A5N4DC38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Camelus dromedarius|TrEMBL
PAPRGCGSHAHRSSSTTCSSSTGTPCTPPSSSFTATLDPSAYPLPARIRASRDWPRLCHV
ALSSLGKETGSGCRRVGRGPASHDGGGTASNVTSGRGHVGGGASRRQRGWCPPSGPASPR
QPDTCASPPTXXXXXXAPRPLRWCPQSGQAAATCALSESSATRSRNSAMVNEPRGNGGPN
PRSEGSSSGSESSKESSRCSTPGLDPERHEKLKEKMKRRMESGDKWFSLEFFPPRTAQGA
VNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQ
SREEITGHLHKAKQLGLKNILALRGGDQWEEEEGGFNYAADLVKHIRGEFGDYFDICVAG
GAPLSLLPSLSAGYPKGHPDAESFEADLMHLKEKVAAGADFIITQLFFEADTFFRFFKAC
SEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAV
SLCRELLESGLVPGLHFYTLNREVATMEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVR
PIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGK
ELTSEESVFEVFVRYLSGEPNQDGYKVSAAGMGVLPASPRPVTCLPWNDEPLAAETSLMK
EELLRVNRRGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKVWHGSMSVPPWDAPGSLP
QAYLEFFTSRETTEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREI
IQPTVVDPVSFMFWKDEAFALWTEQWGKLYEEESPSRMIIQHIHDNYFLVNLVDNEFPLD
NCLWQVVEDTFELLNRAPQNEREMEAP
>A0A8H7S9E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor circinatus|TrEMBL
FIILNMKVIDKIAKAENEGRFYYSFEYFPPKTPQGVQNLYDRMERMQRFGPEFIDVTWGA
GGTSADLTTELVSTAQSVYGLETMMHLTCTNMPIEKIDDALKAAKNCGCQNILALRGDPP
KGQTNWESVENGFEHAIDLVKYIRKQYGDYFCIAVAGYPEGHIDNPDKEADLRYLKEKVD
AGADVIVTQLFFDAEVFLDFVKRCRDIGIKCPILPGIFPIQNYNGLKRVISFSNNAVPQK
VWDDLEPIKDDDSAVKEYGINLAVDFIKKFREAGINGFHIYTFNLERSSRLILERLDLVP
TTESVKPLPWNPSLTSKRAKENVRPIFWKNRQKSYIQRTESWDEYPNGRWGDSRSPAFGE
LDGWGVSLKYPTQDCLKMWGEPKSADDVALTFAKYCKGVISGIPWSAQQLEPETEIIRQR
LAGINLLGYLTINSQPAVNGVKSSHDVYGWGPNNGYVYQKAYLEFFVSPEKLEELTTKIS
KNPQVTYYAVNKRGDLKTNTQNDQPTAVTWGVFPGKEIIQPTIVESMAFMAWKDEAFELW
NEWARIYDRESESAKITLDIMNNWYLVNIVHNDFQDENGIWGLFDLEVDQIAKKTQHLFD
LIP
>A0A8H7SBW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor circinatus|TrEMBL
MKLTQKLQQAHDEKRLSYSFEFFPPKTDAGLANLFDRMGRMARFEPDFIACTWGAGGSTQ
ERTLEVCSTAQSVYGFETLMHLTCTNMGKDKIDRALKDAKAAGIQNILALRGDAPRDQEY
WTPCDQGFTHASDLVTYIRQQYGDYFCIGVAGYPEGHLDTPDKTQDLKYLKEKVDCGADF
IMTQLFYNVDSFIEWVQSCRTMGIHVPIVPSIMPIPTYQSFRRIINLCGIQVPKPILEAL
DDIKGDDQKVKDYGVDLAVDMIQQIQKSDLGISGIHISTLNLERSAKLILEKLNVAPKQP
PVNDLKKVPWMTIRDPSHIENWDEFPNGRYGDARSPAFGENTYLGTQPLPTSKAAAKWGY
PTTPDDITQLFEKYILGQLNTLPWCEEPLQTETDTIQQQLIQMNRNGYWTVGSQPVVNGV
SSRDPVYGWGPANGYVYQKAFLECFVSDKQLNGLLERLKKDPFVTFYASNQKGDFITNVN
DAEAQNAVTWGVFPGKEIVQPTIIERVSFESWKEEAYGLWKEWEQQYAPDSKTAQLLRDI
GERYWLINVVHNDFQEANSLFEAMLP
>A0A6A5WD12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amniculicola lignicola CBS 123094|TrEMBL
MHISQKLAQARAEGKPTFSFEFFPPKTSQGVQNLYDRMDRMHGLGPQFIDVTWGAGGHLS
QLTCEMVKVAQSVYGLETCMHLTCTDMEKSKIDDALKEAYQSGCTNILALRGDPPREKEK
WEATVGGFRYARDLVKYIRERYGNHFDIGVAGYSEGCEDNDNVDELIDHLKEKVDAGATF
VITQMFYDTDIFLAWVDKVRAKGIDIPIIPGIMPISTYAAFMRRATWTKCVVPPHWTAAL
EPIKNDDVEVREVGKGLVVEMCQNLIKGGITHLHFYTMNLAQATRMVLDELDILPDIESP
LEKPLPWRPSLALNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDARSPAFGELDA
YGIGLKGTNEQNIKLWGRPNSIKDISDLFVSYMRGKLSSLPWSEQPITTEADSLQENLID
LNRRGFLTINSQPAVDSAKSSDPIFGWGPRNGYVYQKAYLEVLVSPEHISELTTRIERDP
DLTYYSVNKEGDLKTNAPGEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYKLGDEW
AKCHAAVSPSRYVIQNIMDTWYLVNIVHNDFHVTHGIYPLFEGLSVKDIDQPLLLNGDSK
ESEVVQNGDKTEKSVLNGVVDKAKTASAAVINGLNGLTVSG
>A0A6A3NIN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora rubi|TrEMBL
MTWGAGGSSAQLTLELSANAQKLSGLEMLMHMTCTNMAEADIRKALDQAKAAGIRNILAL
RGDPVRGATSFDECDRGFSHAVDLVRYMREHYGDHFCIGVAGYPEGHVESSDKKADVQYL
KEKVDAGADFVITQLFYDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTAFCNT
FVPQEVRKALEPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEG
LSSLSSRVPRRELPWQTSTLSKRAAESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSES
PAFGELTESHFAPSSTSTPNERRAMWGEAPAAKEDIRRTFVQYVRGEISSLPWCDAALHA
ETSTVQQELAAANSAGFLTINSQPRVNGVLSDDPMFGWGGLGGRVYQKAYVECFVSPENM
KIIIENAAKKPSVQYHAVNLNGHSYSNASKSAIAVTWGVFPNKEILQPTIVDSSSFLVWK
DEAFALWLKLWASLYEDGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSPATS
P
>A0A6N3HWE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytobacter massiliensis|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAVPHLTCIDATRDELRAIARDYWNNGIRHIVALRGD
LPPDGGKPDMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFA
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A701J2Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRNSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A653D8V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callosobruchus maculatus|TrEMBL
MREKFIQADAKAAVESQSEQAESTPVVVPPNRLSELCPRFCSVTWHPTPGHRSETVESIP
ALQLAKRLRKHGHEVLLHLAGRNLKKYQVLVVRIIEHDDNKCDFPYAADLVRFIKSHYQK
TFTIGVSCGSDFIITQASYSYSSYENFVKICRSSGIKVPIIPGMFLVKSHRSLLAISEFC
AVPIPPDVLRTFSNNKGNNEAVLNFGVDLAVELVRKFLTRKDLYDGVHFFCLNDLDVVER
VIRTLRMYEGHIERPVGESECVYIKYYQERSGTDR
>A0A4Q0UGL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter skirrowii CCUG 10374|TrEMBL
MFETLISKLQDGKYLTLETTPQHEPSMHNIVEKIKKFKIDSKVDGFTCTDNPLAKLKYNS
LFAALKLQTEFKKPVIATMTMRDRNKIALQSDLLGANDFDIRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFAVVNAYAKNFGSLEKKMNLKI
QNGAVGVITQPVFDIENVKKLLESFEIAKENVEGDKKKSQLILGLFPITKLRTALFLSAQ
VPGIHVPQFWIDELERAHSISEEEEYKVGMQLSKNLFKEINKIHPKIHLMTANNKFEVAS
EILD
>A0A1G5A7M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. EL159|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAARQQLYVRKPQFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGMGGEFLYASDLVAFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
VRKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTESIKSFGLDVV
TDLCARLRDGGAPALHFYTMNQSAATLALLERLD
>A0A553KWS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliiglaciecola sp. M165|TrEMBL
MVSYAQGIESLNQSLSELSGINVSFEFFPPKTEQMEQTLWKSVNRLAPLKPAYMSVTYGA
NSGERDRTHDVVKRIQQETGVPAVPHLTCVDASREELVQIAQDYWNSGIRKIVALRGDLP
AGMDKTEMYAADLVSLLKDVADFDIAVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIS
QFFFDAEVFLRYRDRAAAAGIDLDIVPGILPVTNYQTLQRFAGFTNVHVPSWLHKMYDGL
ESEDQTTRNLLGASIAMDMVKVLAKEGIRDFHFYTLNRSELSYAICHLLGVRAQNG
>A0A0S8IBQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium SM23_ 63|TrEMBL
MTENMTNGYKSGSRLERILRAGHFAVTGELGPPQGADGDVIREKAHLLKGFVDAANITDN
QTAIVRMSSIGAGTIVVQEGLEPVIQMTCRDRNRLAIQSDLMGAYACGMRNVLCLTGDHQ
SFGNHPTAKNVHDLDSLQLTQMVVKMRDEKQFQCGDEMEGIEPRFFVGAAANPFGDPFEW
RPYRLAKKVKAGADFIQTQLIFNTERFAEYMEKVRELGLHKQTYILAGIGPLKSPGMARY
MRDQVPGLDVPNIWVDRMTEATVGIDKDDKKARRDAWRREGIQIAIDLIKELKQIEGVAG
VHIMAIEWEEAVKPIVEGAELLPRPEPAPLPKSDTA
>A0A1G8A7J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. BP1-148|TrEMBL
MHPIMAVANLITKNSDEHQFSFEVLPPLKGTGTDKLFADIEKLCKLNPAFINITTHHSEY
VYKELSDGRFERQRMRRRPGTIAVAAAIQQRFQVPVQPHVICSGATIEDIEYELLDLQFL
GITDLLLLRGDKAKEDRVFTPTPGGHAHTTDLIRQVQRFNEGFFANGEAIKNPGAKFDIG
VACYPEKHEEAPNLEMDMQYLKEKQDLGAQYAVTQLFYDNEKYFAFVDKARQMGITIPII
PGIKPLAKLTQLSVVPRTFHCDIPEALAREIVKCKTDADARKLGVEWTVKQCQELYAHGV
NDIHFYTVGAVDSVVEIVKELRR
>A0A2I0GF36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. Choline-02u-9|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALSA
RGTTEIAPHMSCIGDDKSEIAELLEYYKTLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
YIREHSGDHFHIEVASYPEMHPQARSFEFDIDNLVNKYQAGANASITQFFYNADSYLYLR
DKLEKRGIDTVAQPLVAGIMPITNSSNLLRFADSCGADIPRYVRKQLTDFGDDRKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLTA
>A0A0S8I3G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium SM23_ 63|TrEMBL
MKITEIWKTSGKPTVSFELFPARSDKAAERLDKTIDELTTLKPDFVSVTFGAGGSTREGS
RQLIEKLKNEKGLEVIGYFAGYGLGPGDIHAVLDSYHVVGVENLLVVRGDPPQEGDFTPH
PESLPYASDLMAFIRPKYDFCLGVAGYPEGHIDAPSLAKDIEYLKLKVDRGAEYIITNYC
YDNQFFFDFLERCTAAGINVPILPGVMPIYSVKMMETLADLCGATITDELRQGIGDLPEE
DKEALLTFGIEFAIRQCRELIEAGVPGLHIYTMDRSKSAVGIVDRLHSDGLL
>A0A218Z664|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marssonina coronariae|TrEMBL
MHIKDMLSESQHADQPTFSFEFFPPKTAQGVQNLYDRMDRMHAFGPSFIDITWGAGGRLA
QLTCEMVSVAQSQYGLETCMHLTCTDMGREKVDAALKEAYKAGCTNILALRGDPPRENEN
QKWVAAEGGFQYAKDLVKHIRETYGNHFDIGVAGYPEGCPDQDDAELLLEHLKQKVDAGA
TFIVTQMFYDVENFLEWVGKVRAKGITIPIVPGIMPINTYASFLRRSVHMGAKIPPDWSA
ALEEVKNDDAAVRNIGTGLVAEMCRKIVKAGIHHLHIYTMNLEQATRMLLEELNLTPSDA
RPLKQALPWRQSLSLGRREEDVRPIFWKNRNKSYVTRTQDWDEFPNGRWGDSRSPAFGEL
DAYGIGLKGSNEQNRKLWGEPRSVKDIADIFVKYLEREVNSLPWSEAAITVEADSIKSDL
IALNKRGLLTINSQPAVDGVKSSDPVYGWGPSNGYVYQKAYLELLVPPTLMDKLISRIEL
DPDLTFYAVNRVGELKTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGK
DWAHCHSALSPSRQLIDNLMDTWYLVNIVHNDFHQTHGLFPLFDGLEVENIDAPFEALPE
TNGTVPVSKPLVATNGATPAGKENAPLTNGSAAH
>A0A2N8SSW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MNEPQSKPSISFEFFPTKTDAGHEKLMATARRLAECKPDFFSCTYGAGGSTRDRTLNTVL
QLDGDVKVPTAPHLSCVGDSKQELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYA
NELVEFIRAETGDHFHIEIAAYPEMHPQARNFEADLANFVRKAKAGANSAITQYFFNADC
YFYFVDRVRKLGVDTPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDAESIQ
AFGEQLISEMCEKLMAGGAPGLHFYTLNQAEPCLAIWDNLKLAS
>A0A1Q5EPW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora sp. CB01950|TrEMBL
MALGIPSTRSDRAQTVRDLLAAGDRSFSFEFMPPRNEEGERKLWDAIRRVEALDPNFVCM
TYGAGGSSRGRTVNLVGRIATETTLTPVAHLTAVDHSVAELRNIIGQYADEGVRNVLAVR
GDPPGDPMGEWVRHPEGVSYASELVELIKGIGDFCVGVAAFPQMHPRSADWDEDIKHFVA
KCRAGADYAITQMFFEVEDYLRLRDRVAAAGCETPIIPEIMPVTNIRQLVRFPQLSGSDF
PPEFRRRLEAAAENPAEVRAVGLEHATAMAERLLAEGAPGLHFITLNHSTSTLEIYQNLG
LHTR
>A0A1Y4JFS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. An19|TrEMBL
MKVINLIKSSEKTAFSFEILPPLKGTGIEKVYETIDLLREFDPKYINITTHRSEYVYTEL
GNGLFERKRVRRRPGTVAVAAAIQNKYGIPVVPHVLCSGFTREDIEYMLLDLQFLGITDL
LVLRGDKAKHQSVFTPEPGGYSHAIELENQINDFNRGIFIDGSPIKEPVHPFGYGVACYP
EKHEEAPNMEQDIYWLKQKIESGAQYAVTQLFYDNAKYFAFVDRLRAEGINVPIIPGIKP
FGKLSQLSVIPKTFKVDLPQTLVAEAMKCHTDAEATELGVEWCINQCRELMRHGVPSIHF
YTVGAAQSVSRVAKAIY
>A0A228HCS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. AU15512|TrEMBL
MKTIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVM
>A0A6C0GP53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocytophaga rosea|TrEMBL
MTKVTQVIKDAQNKTLFSFEILPPLKGESIHSLFEAIEPLMEFKPPFIDVTYHREEYIYK
KRENGLLEKISTRKRPGTVGICAAIMNRFHVDAVPHIICGGFTKEETENALIDLSFLGIE
NVLVLRGDPIKTEPTFSPEPDGHHYATDLLKQVCNMNKGMYLDEEMKTPIATEFCIGVAG
YPEKHFEAPNLRTDIKYLKKKQELGADYVVTQMFFDNEKYCDWVNKCREEGITIPIIPGL
KPITTKKQITVLPRIFHIDIPDALAEAVENCKTDAEAKQVGIEWCIQQSKELMKFGVPVL
HYYSMGKSDTVKKIASALF
>A0A7X1H2Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MDLKRKLETKDFAILAEIEPPKGSDIAAMVNNAAKVKEEVTAFVIPEMSNAVMRMSALGA
AMVLEAKRMETVMQVCCRDRNRIALQADLLAASACGINNVMAVTGEDPSFGDHHQAAAVY
DIDIDELLKTIQGLEKGKDMAGIELSGSPDFTVGSMVNSGLEGTDLDREIDAMKRKIDAG
VRFFITPPLFDVSAIEPFMNKINTSGIHIIPTVVLLKSLGMARYMARNMKHVYIPDELVK
RIQKAPDKVRECIRIAKESVSAVKKNGFSGAMISTIGWEDRLYDIIHGI
>A0A8F8B999|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus altitudinis|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSLDEIKR
SFREQLYILLNEEPDGLLLETYYDIEEAKAVLEIARKETALPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPLLENSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSAIEFRNQGARIIGGCCGTTPQHISAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKSAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
PDSIREIMAKAGENKEKQRTEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKEPNIHANYH
>J8H4F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VD014|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVADKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAEALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDISVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNGGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>M1PJE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocapsa sulfexigens (strain DSM 10523 / SB164P1)|TrEMBL
MKSGSKLETLLKEGTFVVTGELGPPKNGNPEVVREKAQLLKGNVDAVNITDCQTAIVRMS
SIAAGLIAKEEGLEPVIQMTCRDRNRIGMQSDILGASALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQMLGMMKGMRDDKIFQCGEEIKSNEPKLFLGAAANPFAYPFEYRAVRLGKK
VAAGADFIQTQIIYNVEKFREFMKMVRDLGLHEKCYILAGVTPPKSLGMARYMKKFVPGM
DVTDEVIQRMKDAKDMQDEGIQICADIINEVKDIEGVAGIHCMAIEWESAVPEILKRAGL
LPRPGITETDAAVKPIATDEVKEQITVQSVDTDTLLEKAKAEAAAIIAAAKAEAENLKQK
AAAVSSVATATTSITTEAPQGVDDSGEHEMNEKERIMALDSVNLGLAALKKAYGLTDDQF
EALSSFAGAHAILKKEPEVVSSAPVAPVAAAAPQAPAAPAAPAAPVIDDSAEKAKAEAAA
KAKADAEAKADEEAKLKAAAAAKLKAEAQEKAAADAKAAADAKAADEAKAKAAAEEKAAA
EAKVKAEAEAKANVQAAPAPVADSGVGELAKETVSLADRSTKVAPANYETKYSGELRSVK
LGNEGNEKIVGGSSSMPFHLFEGDHPNKPLIAMEVSDVKPDEWPETLSRHFSDVFDNPVA
WAEKCVKVYGAEAIAVTLGSTDPNGMNRSAADAAKTAAAVIAAVDVPVIVWGCGNSDKDT
ETLRDITSVIGDKKVCLAPLEDSNYRTIGATAMAFQHPIVAASPIDVNLAKQLNILLENL
GVSLDTVLMDPSIGALGYGIEYTYSVMERIRIAALTQQDAKLQVPIICNLGCEVWKAKET
KLPSDDMIGDQETRGIMMEALTASCMLMAGGEVMIMRHPKAIALTNAMVAGLMD
>A0A848Z2U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MNLQHRLSSGKFVILAEMHTPKGVDISDLITNARGLKGRVDAVIIPDMDNGVMRMSALAG
GALISREGIESMIHIYARDRNRLALQGDILAAHVLGIKNLLVVQGEEMRLGDHREANPVD
DMDELELIRTVKTLQGGKDSAGFDLAGKPSFGVGCTMSLWTSDRELDLELEKTAGKIEAG
AQFIILPPMFEAEQLVAVIEKIRGFRVPVISTVFILKSVGVARYMSLKMDGINIPEELIQ
RIRKAGDREDECLRIAGETIAAFGQLSQGVRIETMGWEHKLPIILDYAGR
>A0A3D6CAY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSELKSGSNLEKVLAAGHFAFTGECGPPKGANVEHLVEKFQHLKGNVDCVNMTDNQTAVV
RMSSMAGSALMVNEGLEPNFQMVCRDRNRLAMMSDILGAYALGVRNMLCLSGDHQTFGNH
PEAKNVHCIDSMQLIAMVKKMRDEGKFLNDEDIDVPPKMFIGAACNPFADPYEFRPYRLA
NKIEAGADFIQTQCIFNMEKFRDFMSKVVDMGLHEKCYILAGVTPMKNAGMANFMKKFVP
GMDIPDELIKRLKGVEKKDQAEEGIKFALEQVEEFKEMEGVAGVHMMAIEWEHKVPEIAE
RAGVLPRPVID
>A0A6F9B1M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coregonus sp. 'balchen'|TrEMBL
MVNQVQRVEDTWRTCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTEL
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKHLGLKNIMALRG
>A0A7X1GKB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLEKILSSGQFSVTAECGPPKGTSAKVIQKKGELLKSYCDALNVTDNQTAIVRMS
SLSGCVILKQVGVEPVMQMVVRDRNRLAIQSDILGAVALGIRNVLCLSGDHQKFGNHPTA
KGVYDIDSMQLLQTLKHMRDEKKFLSGDDISGEVPLFLGAAANPFADPFEFRVTRLAKKI
KAGADFIQTQAIFDVPKFIRWMDMVRDRGLDQNVHILAGVIPVKSVGMARYMRNNVSGLS
VPKELVNRMADAKDAKEEGVKICLEIIEQIKEIKGIHGVHIMAVAWEDIVPGIVEKAGLM
PRPIKH
>A0A7X1L857|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSFQRRLASGDFVVLAEMNTPKGVNVAELVANARKIKGRVDAVIIPDMDNGVMRMSALAG
GALIHQQGMEAIIHLYCRDRNRMALQGDVLAAHLLGIRNLVVVPGEEMANGDHRDATVVN
DLDELELLGAIRSLQNGVDMSGFSLNGNPEFMTGCTLGAFADEQALDAELAALEKKVAAG
AGFVITPPVFDVERSAADLEKIAALKVPVIATVFLLKSVGIARYMSLNEPGAHISEEMIK
RIRKAPNREMECQRIAGETIAQLKNLVQGVKIETLGWEHKLPTILGFAGL
>A0A839TC02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter luti|TrEMBL
MTKPAISFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALCA
RGNTDIAPHLSCIGDDKSEIAELLDLYKSLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREYSGDHFRIEVAAYPEMHPQARSFELDVENLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTIAQPLVAGIMPITNSSNLVRFADSCGADIPRYVRKRLTDFGDDRTAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLIEALGLTA
>A0A848ZFD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MALQERIKSGKFVVLGEFEPPKGADFSPLLKSANLARGRLDAVLIPEMANAVLKASSLGG
CAFFQKEGIETVLQLCCRDRNRLALQADVLAAGALGIKNIMAVSGEDIRFGDHPQARTVN
DLDLLELLQAVQQIQEGKDLAGIELRGSPTFCLGSTIDAGAPGGLLDIELENLNKKIEFG
VEYVVTNPIFDIRLFQQFIKRVDTSKVGVIPTILLLKSAGMARYIDRNIKEISIPSDTIR
GIQKASDKVKECIRIAAELITRMKEMGMAGVLISTVGWEDRLPQILDEAKL
>A0A7C0ZBI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLEKILRAGHFAFTGELGPPRGANDAAVREKAKFLRGMVDSVNITDNQTAMVRMS
SWAASLVALQEGLEPNYQMVCRDRNRLAMQSDVLGAYALGIRNMLCLSGDHQQFGDHPRA
KSAYDIDSTQLIQMVRKMRDEAKFQGGAEIDTPPKMFIGAAANPFADPFEWRVHRLAKKV
KAGADFIQTQCIYNMDKFRRWIQQANDMGLTEKVFILAGVTPMKSVGMARYMKLKVPGMD
VPDEIIKRLQGVDKKKVADEGIRIACEQIAEFREMKGVAGVHLMAIEWEHKVPEIAERAG
MLPRPQV
>A0A525DBD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MLRIFNDELMNPNNFVVTIELVPGRESFGRSTDTLVGIAKDAFADGRVSAVSITDNPGGN
PSLSPDVLGYEIFRHGLDVIVHFTCRDTNRVGMESRALQLARMGMKNILCLTGDYSGKGF
GGRGTPVFDLDSVLLTRMMQGLSERLIASGDPEPFFTGCGVSPFKSLRSECMAQYKKLDR
KIEEGAAFVITQLGYDINKFNELIRHHNEKNSHVPVMGSVYLLSPRAARAMNRGRVPGAY
VSDPLYEKVVEEWHTPREGLQAAIERAARLGVVLKGFGYRGIHIGGVHKSFRTIARILDR
MEEIEDDWPQYMTEFAAKEKQVYYCYDRVTSDEDNPGRKPGIKEQVLEHWPYVMLRSAHN
LFFDKENALAPFHRKFARFLDTHDKTWILKRCMEDPMKGALLSCQSCGDCGIQHAAFLCP
ESQCPKHTRNGPCGGSRDGSCEVYPEKDCIWIRAFRRLEHAGRLDHFLEDKVPPRNWELN
QTSSWINFHLDRDHQK
>A0A7V1WW54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MNDLKSGSNLEKVLKAGHFAFTGECGPPRGANVEHLREKIAHLKGMVDAVNVTDNQTAVV
RMSSWAASTIMIREGVEANFQMVCRDRNRLAMQSDILGVYAMGIRNMLCLSGDHQTFGNH
PQAKNVYDIDSMQLISLVRKMRDEGKFMNDEDIDVPPRLFIGAASNP
>A0A1N7JHJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kaistella chaponensis|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERKITRMRPGTLGICSAIQHKYGVDTVPHVLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGQQYFEATSGGHKNAMDLVLQINNLGRGKYLHDENILEDDNKFCIGVAGY
PEKHIEAPSMNYDLKWLKEKVDAGADYIVTQMFFDNKKFINFVKEAREMGINVPIIPGIK
PIATKGHLQMLPKVFKIDLPEDLISAVEKAKDNAAVKQIGIEWTINQCRELLDFGVPVLH
FYSMGKSDNIKKIASELF
>A0A1E3AS11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eisenbergiella tayi|TrEMBL
MKISDIYNKKKSLSFEIFPPKKDSELENIDETLKVLCELNPDYISVTFGAGGTSNCNRTI
ELAKKIKYEYHIEPVVHLTCLHYDKSEIDKFAKILIDEEIQNILALRGDKNPSIQEKGVF
KHASDLITYLKSKHDFCFLGACYPECHPESDNKINEMKHLKKKVIAGTEILLSQLFFDNE
QFFSFVEECRIADINIPIIPGIMPVINTSQIKRMVTLCGATFPERFQKIILKYENNKKAL
FDAGIAYALSQVIDLLANDIDGIHLYTMNNPLVASKICEGIRNII
>A0A1F8MVC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_53_26|TrEMBL
MNLQEKLASNKFVVTTEIGPPKGVDISEMHETAEILKGRIDAVNCTDQQASVMRLGSLAS
CHLVKQWGLEPVFQMTCRDRNRIALQSDLLNAHVFGIENVLCLTGDHICLGDHPQAKPVF
DLDSVSLLQALKLLGTGQDLGGKEVKGNPQYFAGACVTPGADPLEPQIIKMEKKVKAGAQ
FFQTQAVYEPRKFEEFMNAVKYLNVPVLLGIVLLRSAAMAHFMNKNVAGIHVPDSLIEEM
DKAEKKQAKGIEIAARLIKDMKSMCQGVHIMAIGMEKRVPAILDAAGL
>A0A518C5E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bremerella volcania|TrEMBL
MLSDFYKPGQLPISFELYPPKTDKGVRSLMLQVERLMKHKPAYITCTYGAGGSTRGKTLE
IVEKVKTLFQVPVAAHLTVVGSSVADLRSFLAEAERRGVDYIVALRGDPPQGETKFKPNP
KGLRYANELVELINDEFNELGVLVAGYPETHQEAPSPEVDLENLKRKVDAGAQVIVSQLF
FRNSDFYSWRERCEKAGITVPIVPGIFPINSLAQISKIAKMCGAGIPKKLYEKLNQKPDD
PEWHKRVGTAYASQQVNDLADNGVPGFHFYVLNQAEATGKILTALKEHMAKKKSGSPA
>A0A3A4Q1S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKTESRLEKILAAGHMAVTSECGPPRGALPEKVKEKAEMLRGCVDGINVTDNQTAMVRMS
STAACIIIKQMGLDPILQMVTRDRNRLALQSDIIGAYAFGINTMLCLSGDHPRFGDHPMA
ANVYDLDSVQLIQTVKKMRDEGKFQGGADIANAPKMFIGAAANPFADPFELRVMRLAKKV
NAGVDFIQTQCIFNLDKFELYMKQVCDRGLHEKVAILAGITPMKTAGAARYMKNKVPGMD
VPDEIVKRMEGQPKEKQAEEGVKIAVEAMQRIKEMPGVRGFHIMAIEWEQKVPEIVERAG
LLPRPEV
>A0A3Q9NPF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MSQANLSTLLKSARYEILPTAGVVDRVHEYVAPGRVITVTASTGLTLEATLSTAEQLQAL
GFQAVPHIAARMVQSRTELEEIVARIAQAGIDRIFVPAGDATPPAGGYAGALDLIVDLAS
MAAPIQHLGVSAYPETHPLISDDVTVQAMWDKRDYATHLVSNLCFDPGVIATWLARVRAR
GIELPLVLGIAGKVELTKLARVAGKIGVGESTRFLRKNTATFSRMAKPGGYNPQKLLDKL
APTLDNPAMGVVGLHIYTFNQIKDTEIWRRKQLAALGHTDEATISNG
>Q8YYR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)|TrEMBL
MDDNHSYTALNYFSKAAQAGEFLVTAEVAPPKGGNPTHMIEMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQQGIEPICQMACRDRNRIALQADLMGAHALGIRNILALTGDPVKA
GDHPEAKAVFDLEAVRLLQLIRKMNQGVDCNDKPLTDGATDLFVGAAVDPQCASWSGLQS
RFERKIEAGAQFFQSQLITDFEKLEKFMDKIASTHKKPILAGIFLLKSAKNAQFINRCVP
GVNIPEHIIDRLAKAKDPLEEGVKIAAEQVQTARQLCHGVHMMAVKREDLIPKILDLAGV
APVNQLVAK
>A0A416N083|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF24-32LB|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>D3D6R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. EUN1f|TrEMBL
MRESTTSHEQPARGFELICEIEPPTRPDLTHARHQIGVLSPVADAFLIPDNHIGRATVSS
IAVAHEVQTMGGRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVRGDKPSAGNRTGDL
TVRAMIDEARAAGEDPVFADMPAFRVGAAAGLRPLPAWKQAVDFLFVQVSYSVDALLRWR
DAHPVELPVYAGVMVLASAGMARRLAATIPDIDIPDDLVQAVERDRAAGVEAACDQVLQL
RDSGAFAGVHLVPVSRYRQVATRLEDLL
>A0A358BXX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcales bacterium UBA8138|TrEMBL
MAPGFEQALAGPRPVITAEITPPLGGDPSRALAAAESLRGLVQAFNVTDGSRAVMRMGSL
ALCKLLQERGLEPVLQLGCRDRNRIGLQAELLGAHALGLRNVLCLTGDPVRAGNQPLARP
VFDLESVRLLQQVQALNQGLDPLGKVLPDGPTSLFAGAAADPQSPSWSGLKSRTARKAAA
GARFLQTQMVMDPEALRRFCGEITSPLGLPVLAGVFLLKSAKNASFINRVVPGAQIPQAL
IDRLAAAADPRLEGIRIAAEQVSSYCKIAAGVHLMAIKAEESLVDVLALAEI
>A0A0H5SKJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbinix hemicellulosilytica|TrEMBL
MDAENLDQDIMYLKKKVEAGAQHLISQLFFDNSYFYNFLEKAREAGIDVPIQAGIMPVIN
KAQIERMVTLCGASLPPKFTKMMQRFEHSPEAIREAGIAYAVDQIVDLVSHGVDGIHLYT
MNNPYVARRISESIKDIIKA
>A0A1F5DC49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon RBG_13_60_20|TrEMBL
MTNRPAYSQLVKDLRSGKFVLTGELEPEKVTSLDEIIISAKAMKPYVVAANVTDNPLAFA
YMNSLVPSWVIQKEVGLEAVYQMTIRDRNRLAIVSDVLAASYLGIKNILAISGDHTVLGD
NRGALSVYDLDSAQFVYLLHKMIDEGVDLAGNEIHGKVGINVGIAANPNADPLMPEVLKI
GRKTKIGADFIQTQTMFDIDKTKTFLKEVEKYNCPVLVGVFPLKSFGIADFFDKNIPGVK
VPPELLASMAKAKEEPDKERRSALYDEVNLEFFVPFIKEIRKTTKASGIHIMAVLYERIF
GPLLENF
>A0A7V9S7B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MDLVGELQDSLICGDGAMGTLLLDRGVALERCFEELCVSEAARIQEIHEEYIRAGARVIE
TNTFGGNAVRLERFGFEARVEEINRAAARIARNAASGKNICVAGSIGPLGITADEAAARG
IDRAACFGAQIAALAEGGVDVLFFETFMDFDEMEIALRRKSELTDIPAIASFACAAEGRL
ASGVLIGEAFARAQELGAAIVGANCMNGPHAMVQLLERVPAGFITAAYANAGYPKYHEGR
FIYYTAPDYFAGAAREMVAQGARLIGGCCGTNPKHIRALAAALAALEPVRNKVVRVIESA
PVVAPTKPSAVVEESLLDRIAAGKRVIICELDPPKTLALEKFFTGAQALVRAGCDAITLA
DNSLAILRVSNLAIGAMLKERFGIMPLLHLSCRDRNVLGLQSELLGMAALGMRHVLPLTG
DPARVGDHPGAASVYDVNSVGLIAIIKRLNEGFSQAGKAINRATGFVIGCTFNPNAKNMD
AQVQRLERKVAAGAQYAMTQPVFDIRLVEKMQQRTAHLPIPIFTGVWPLLSGRQAEFLHN
EVPGIVVPDAVRSDMAGREGEDGRACGVKLAQEIARAALARFPGVYLITPFLQYQTTVEL
AGFARSI
>A0A850JRA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. BRA 177|TrEMBL
MGFEVVCEVEPPTRPDLRKVRHQIGVLSPVADSFLIPDNHIGRATVSSVAVAHEVQAMGV
RGIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVYGDKPSAGGRTSELTVRAMMEEARAA
SEDQVFAGCAPFQVGVTSGLRTVPEWKRAADFTFVQVSYSVESLLRWREAVELDGPVYAG
VMVLASAGMARNLAAAIPDIDIPGELVDAVERDRAAGVAAACEQVLAIRDTGAFDGVHLV
PVSRYREVAARLEREL
>A0A8C3EAQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corvus moneduloides|TrEMBL
LMFGIGAVMPAKKTKDSLWGWPAVPAPCRDPCADHTPSAPLSRALTMVNETQHTCSASSS
SRSDGGSSSGSESSKDNSRCSTPVLDADRHERLRDKMRRRQDAGDKWFSLEFFPPRTANA
AVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCN
QTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDI
CVAGYPKGHPEAESYEADLRHLKEKVFAGADFVITQLFFRPETFLKFMKDCQAIGITCPI
IPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDS
GMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPK
SYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTCEESVF
EVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGILTINSQPNINGKP
STDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAP
DLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYI
HDNYYLVNLVDNDFPLENCLWQVVEDTFELLNSPTQQ
>A0A7K9ND29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edolisoma coerulescens|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A2H0ABF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG23_combo_of_CG06-09_8_20_14_all_60_8|TrEMBL
MDCGPPGAFASHRHTRKQRHKAIMNNAHCFQTSLRDPEDFTLTFELVPSRGGRSHEHGRA
LDFAREAVQDGRLRAVSITENAGGHAALSPEVLGVEILHLGLDVIVHFSCKDKNRNQMES
LLFAWDRLGLRNLLVLAGDYPKPGYQGLPKPVFDLDTVQALDLVGRMNQAIFGADQLSAL
ADPAEATAFFRGVVVSPFKYLEAELRMQYAKLHRKAAAGAGFVITQLGFDARKFQEVLLY
LRANHLELPVLGNVFIPNLTVTELMYRGEIPGCVIPAALYRQIRQEAASTDKGKGARLER
AAKLLAVLKGLGFAGAHIGGPALVFADVKRVMDRAEELAADWSACLPELHFWPDDSFYYF
KRDKASGLNQLEPSPTAGRIAGRLSGYDLTRRIHDLAFAPVGPLHVPVKKLCLALAATRL
APGMAGLEHLIKFLAFRCQNCGDCTLSELAYLCPQSGCAKYLLNGPCGGSRDGWCEVYPG
VKRCLYVRVYERLVAHGCFQETLTDLVPPRDWALNNTSAWVSFFSGRDHVHLGEK
>A0A1Z4K0Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix brevissima NIES-22|TrEMBL
MSDTQNPTVLNGFRQAAQAGEFLITAEVAPPKGGNPKHMLDMAATLKGRVHAVNVTDGSR
AVLRMSSLVASAILLQHGIEPICQMACRDRNRIGLQADLMGAHALGIHNILALTGDPVKA
GDHPDAKGVFDLEAIRLLQLIRKLNQGIDANEQPLTDGALDLFVGAAVDPQCASWSGLQS
RFERKLQAGAQFFQSQLITDFDRLEKFMYSVAAGCNKPILAGIFLLKSAKNAQFINKCVP
GVNIPQHIIDRLAKAKHPLEEGVKIAAEQVQIARQLCQGVHMMAVKREDLIPQILDLAGV
KPVNLVVSK
>I4GLL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa PCC 7941|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGSLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPVHN
>A0A1G1HS23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium RBG_16_64_22|TrEMBL
FEFFPPKTPEGEEGLRATIRDLKPLNPSFVSVTYGAGGSTRAQTIDLVSRIKRETGIESM
AHLTCIGASRIELIEILDKLRSDGIENILALRGDPPKGETAFVPAAGGFAHASDLVAFIR
AHDGTFCVGGAAYPEGHVESRSLDEDIRHLKTKVDAGCNFLITQLFFDNRFYFDFVRRAR
TAGIAVPILPGIMPVTNLDQLKRFTSMCGASIPEELMRRLEQAPSVESVRVIGIDHAVRQ
CGELLSRGASGIHFYTLNQSKATREILARIRSPG
>A0A4Y8H1A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. LAIL14HWK12:I2|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVTEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A8QAM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malassezia globosa (strain ATCC MYA-4612 / CBS 7966)|TrEMBL
MSQAEAQLSARIDEKLNDSTQDAYVWSLEFFPPRTALGLANLCARVARMSEALQPGWVHV
TWGTGGSTRDASMELAARVQKGVYDPLEDYTNVKERRKGACDVCLHLTCTNVERAYLDAT
LDEARQIGIRNILALRGDPPRSDEYWVATDQRLQNATDLVRYIRERHGDYFCIGVAGYPE
GLKQGIDCDMRHDIKVLKAKQEAGAHFIVTQLFYDVDALVRWTKECRAAGITIPIIPGIM
PIQNYTMFRRMANLCGVHTPEDVLEQLEPIKMDDAKVKEHGIHLSIDMIKSIREQTGIRA
FHLYTLNLEKSATCVIKVLADVPDQSASISGSVTWDEFPNGRYTDARSPAFGEMDGYGAN
LKVPPEEAVRLWGTPVDEDDISSIFSRFVDGRLACMPWCDIPVWDETMQLLPALLHLNSP
PSAGGKAWWTVGSQPAVDGCDSTDPTFGFGPQGGYIFQKAFVELFMNENDKNALVQMIQG
SSTPVTYFAGKCDPTTFETNLTTNGLNTVTWGVFPGTEVAQSTIIEEASFRAWRDEAFAI
WREWELLFPPNSATRSLLRRIHDERWLVTVVHHDYKDPQGLWRLLETVS
>A0A2I1VVZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium pyruviciproducens|TrEMBL
MKTTELFKRKTVFSLEIFPPKKTASIATVYDTLDGLEGIHPDFISVTFGAVGAGDNTHTF
PIASTVKKYYQIEGVAHLPAIGLTRDQVRERLDEMKARGIDNVLALRGDLPAGGEQPTGH
FPHASDLIAFIREHSDLNIIAACYPETHPECPSRVDDIRNLKRKVDAGASHLISQLFFDN
SRFYGFLERCDLAGIDVPIEAGIMPVVNKAQIERITSLCGAEIPHKFRVMMDRFGDNPRA
MRDAGIAYAIDQIIDLITQGVDGIHLYTMNNPYIARRINDAVSTLIADTPPRAAHRKVFA
LA
>A0A2P8ID80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix carnea|TrEMBL
MTSVVDRLHGNSPVFSVEFFPARDEAEETVLWRAIRELEAFDPAFVSITYGAGGSTRDRT
IRTTSRVAQETTLLPMAHLTLVNHSVAELRNVIGWYAAVGVRNILAVRGDPPGDPNGEWT
AHPEGLTYAEELVRLCRELGDFCVGVAASPYGHPRSADLDTDTEYLVRKLRAGADFAIAQ
LFFQPEDFLRLRDRVAARGCDTVLIPGLMPLTTPRTLAKTVELSGSSVPDSVARRLDPYV
DDPAGFRAAGIDLVTEVGERLLAEGVPCLHFYTFNRSKATREIVGRLGLVPARA
>A0A4R6KG93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2527|TrEMBL
MVTGLPSTRPGSTPTIRELLAAGNRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPSQPWVAHPEGMNHAIELVELIRSLGDFCVGVAAFPDKHPEAADLDADARVLAE
KAEAGADYAITQMFFGADDYFSLVDRAAAYGCDIPILPGIMPVTNIKQIKRMAELTGMAL
PTAVTDRLHAVEEDPKAVREVGIEIASELCEKLLSGGAPGIHFITLNRSTATRQVYLNLQ
GTTV
>A0A4P9VT72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zooshikella ganghwensis|TrEMBL
MESQKKHPKRFSFEFFPAKTPAGQEKLLTTAKRLAEYKPDFFSVTYGAAGSTRDRTKDTV
LAITEATQIDTAPHLSCIGASKEEIADLLNDYKTHQIKRIVALRGDMPSGMGLATGEMRY
ANELVSFIRETTQQQFILEVAAYPEIHPQAPNAEKDLENFKRKVDAGANAAITQYFYNAD
SYFYFVERCEKLGITIPITPGIMPITNYTKLARFSDACGAELPRWIRKQLEAYGDDITSI
RQFGEEVITRLCEQLLDAGAPGIHFYTLNQADPSLAVWNNLDLSNRR
>A0A7C2ZTT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
RLVQEGYEPIFQVTCRDRNRLALQSDILSAYVLGIRNVLALTGDHTMLGDHPQSKPVFDL
DSVSLLMAISSLKEGRDLAGEELDGAPSDIFPGATVTPGADPLEPQIIKMEKKIEAGARF
FQTQAVYDPKTFERFIDQASKFNVPILAGIVIIKSPAMARYMNENVPGVFVPDSIIRSLA
EVPRKERAKRSIELMAQLIRELKPMCQGIHIMAMGWERYVPDLLDACDIN
>E8N465|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1)|TrEMBL
MGGCMKFKELLKEKRPLLSDGAMGTLLHQRGVDFSECFDALNLTNPALVADIHRAYIDAG
SQIIQTNTFGANRYKLAKHGLENQVAEINRAGVDLAQRVVLASFKDILIAGDVGPLGVRL
APFGRVQLDQAYDAFLEQIQALSDAGIDLLIIETMTDLYEVIEAIRAARAVDPDLPVVAS
MTFTRDDRTMLGDSPEKVARRIHEAGADVIGINCSGGPNQILRILKQMRQAVPDAVYSVM
PNAGWPEQVGGRIMYPAAPEYFGEYAQAFCEAGATLMGGCCGTTPKHIEAMAQALHTNPR
PCLSDQILVISNNHQEVTEQPEHPTQLAQKLAQGQFVVAVEMDPPRGFSTHKLLAGASLL
AEAGADVIDVADSPMARMRMSPWAVCDLIQDKIGIETVLHFPTRGRNLLRVQGDLLAAHA
LGIRNVFVVMGDPTAIGDYPTAMDNYDLVPSGLIQLIKQGFNAGVDHSGADIGQPTSFFV
GCALNLNPADPDNEIKNLKRKLRAGADFILTQPIYEIEPAKAFLEQIEVALGGPLPIPLM
VGILPLASSRHANFLHQEVPGITIPEEIRVRMEQAGENGAREGIRIAIELAEQIHTIAQG
IYIMPAFNRFDYAAEIIEAVKSKEPASR
>A0A8J3H0R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Seohaeicola zhoushanensis|TrEMBL
MTTPAVSFEFFPPQNLAASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNASREETLAIARGFAEAGVKEIVALRGDPPKGAGGFVPHPEGFANSV
ELIEALAATGDFTIRVGAYPDPHPEAANAQADVDWLKAKLDAGATEALTQFFFEAETFLR
FRDACAKAGIDKVITPGILPIENWKGAANFARRCGTKIPAWVEEAFEKAIRDDRHDLLAT
SLCTELCSNLLDEGVEALHFYTLNRPEMTRDVCHALGITPRVRLENVA
>M0DAV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halogeometricum pallidum JCM 14848|TrEMBL
MSLQSESKTIDDIDNVETLLGNTRFELMPFESFDEEITHLPEGATIAITTSPQLGIDRTV
EKTEMAVERGYEAVPHVAARYVEDQEHLEEIARRLTEAGVTDIFVPGGDREEPAGEFESA
YDLLTALDRTEYEFEEVGITGYPEGHAFLDDETLWESMARKEPYATYIVTQLCYDPETVL
EWISEVRDRGVDLPVAVGIPGVMKYKRLLEISQKVGVGDSIQFLKKTTGIFGFIRQLIGS
RGTYKPDKLIDGLAPYVPNEAYNIRGVHIYAFNQTADLESWRLERLER
>A0A7X7KHP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pirellulaceae bacterium|TrEMBL
MTSDRFVYGAEIVSSRGPQSHDSPSALASFAKDLLADSRIGWISITDNPGGGPMMPPDWI
AAHVADDPGRVVIHLTCKDMNRSGLESAAWRYASEGFENILALTGDYPTGGYSGLAEPVF
DLDSVALIDLLRSMNEGLTVPGRGGKTETLGKTNFYIGCAVSPFKRHERELLPQFFKLVR
KIAAGAEWIVPQLGYDMRKFHEIKLFLQARGINVPIIGNVYLLTKGVAKLFNSGKLAGCV
VSNELLHKAEKYAAGPDKGKQFFRELAAKQLAVFKGLGFAGGYIGGVHAADGFGPIIELA
ESYGADDWRGFFKEIMFSQVDEFFLFEHDKFSGLCDHAQFNQEYLKSLKRPVKSKQVTLN
YKLSRLVHGMAFTRDRALWPLLKKIYARWDRKPGFLSRMAYRVEKVSKLAMYGCQDCGDC
SLPDCAYICPKKWCSKCQRNGPCGGSIDGRCELEDKDCIWARAYERLKYYGESETMLDRP
PIYYDAKLKETSSWANAFLDRDHSAKKNDE
>A0A7V8LX05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. broussonetiae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A8B4RZA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas testosteroni|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPEFCSVTYGAGGSTQAGTFTMVRDIQNE
GVGAASHFSCIGATHEKVRAELNELKAMGVKRIVALRGDLPSGYGLGGEFQYASDLVAFV
RQGFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VRALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A2E3BD52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleispira sp|TrEMBL
MTKISFEFFPTQTEAGTEKLLKVRDRLAQENPEFISVTYGAGGSTRDRTRSIVHSIQESG
IAAAPHLSCIGDSKADLREILIDYKNMGINRIVTLRGDLPSGAGMANSELRYANELVEFI
RQETGDHFTLEVAAYPEMHPQATSFEDDLKNFERKVKAGADSAITQYFFNPDSYFHFVDR
VQAMGIEIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSESIMKFGEEVV
SSLSQKLLDQGAPGIHFYTMNQAEPSLAIWNNIK
>A0A172U2V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavisolibacter tropicus|TrEMBL
MKVTDYLNNGKSTLVSFEILPPLKGRSINALWEHLDPLMEFKPSFINVTYHRSESMFKRK
VDGTFEKVEVRKRPGTVGICAAIMNRYKVDAVAHLICGGFTKQETEDALIDLAFLGVNNV
LVLRGDAPKNETFFEPEPGGHKYAIELLQQVTNMNNGIYLEEDLKNTVKTDFCIGVAGYP
EKHFESPNFKTDLAYLKAKVDAGAEYITTQMFFDNEKYFAFVDACRNVGINVPIIPGLKP
ISSKKQLTIIPRTFHVDIPEQLSSEILKCKTDADVETVGTEWLLQQSKELKAAGVPILHY
YTLGKPTMVANVVKEIV
>A0A1G3ZKD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium RIFCSPLOWO2_12_FULL_64_8|TrEMBL
MPADRPISELFAQRRPLRSLEFFPPKDDAGVDALRRTAAALKRVGPDFVSVTYGAGGSTR
ERTAHVSALLRDELGFTVMPHLTAVNHTRAEIAAIADAHHARGIRNIMALRGDVPRDLAA
ATAFKDGLRYGSDVVALLKRRHPDLCLGVGGYPEKHPEAPSLDADLAHLRRKVDAGASFV
TTQLFFDNDVYLRFVDRCRAAGLSVPIVPGIMPVLSLKQIKRFTGMCGASLPARLVTRLE
AAGESQPEIVEAVGIDWALAQIRELLARGAPGYHLYILNRAKSALALAAGLAA
>A0A0J7IAU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. BLS98|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTPGGHASAMDLVHQINDLGRGKYLHNDETACDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVTKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAITQCKELLNFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A2M7FRA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium CG17_big_fil_post_rev_8_21_14_2_50_60_13|TrEMBL
YFYNPDAYFRFIEEAHALGVRVPVVPGIMPIASSSQLMRFSDACGAEIPRWIRLRLQSFG
DDSASIKAFGLDVVTDLCEQLRAGGAPG
>A0A0E2BU45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus casei A2-362|TrEMBL
MADIQNLKRKVDAGTSELITQLFYDNQEFYHFQERCRFAGITVPIEAGIMPLMTAKQAAH
MMAGVTIPEKLQALINRFADKPEALRDAGIAYAIDQIVDLLAHGVNGIHLYTMDNPEVAA
RIIEATRNIVRA
>C8Z8C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse)|TrEMBL
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRD
AENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDVKLDLEYLKQKID
AGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQH
FSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANKCLELWSTPTSINDVAFLVINYLNGNLKCLPWSDITIN
DEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL
>A0A2D8V0R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedosphaera sp|TrEMBL
MRXXRXIHQXRKXEGXPAFSFXFFPPKTEKGEXALFGSVLPELQTMAPDXCSVTYGAGGS
TRDKTLDMVXRIQKDFGLVCMSHLTCVQATXEQIAQVLQDAEKRNIRXXLALRGDPPGGV
GXFEATEGGFAYSKDLVAFIRAHXXMSIGVAGFPEGXXACKEGKEXDWGRLKEKVDAGAD
FVVTQLFXXNEDFLRFRDHMVKELGMHQTXXPGILPVLSTRQIQRFTELCGASIPTPMMQ
RLXDLSEDDAAAAAFGIEXAXGQCEELLKEGVAGLHFYCLNKAXSTLXVARALASHR
>A0A199XRS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium succinicans|TrEMBL
MKVTQHIENAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVN
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPTNGGNKYASDLVSQIYQLNQGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQTDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVERHLQVLPQIFRIDLPEDLIAGVEKCKNNAEIRQVGIEWAIQQSIELKAAGVPVLH
YYSMGKSENIRQIASQIF
>A0A2S6SJL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha6_Bin1|TrEMBL
LKISFEFFPPKNLKMYQSLWNTLNKLKIFYPDFVSITYGAGGSTRQRTHDTIKKFTYKPS
IRPIPHLTCIGDTRESIKKLAMKYWELGIRSIVVIRGDSENIKLTKKRTFTTFPNGYKYA
SELVKDLRDLKDFKIIIATFPEKHPESKNFQEDIDNLKRKIDLGATKGITQFFFDNNKFY
DFINLLQKKNIKIPIIPGILPIINFDKLMTFAQNCSAFIPNKIKDLYKKNNKDKFKLSVD
ITTSQCLDLMKNGFRNLHFYTLNQSDLTGKICSNLTKKKILNKDYDAFWT
>A0A2D6CXK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
GLTAICHCTCRDRNLIGQQSELMGGYVLGISHVLAVTGDPISLGGREGTAVFDTNSFGLI
DMLSRMNRGENMGGESIGRPTSFTIGCALNPNRARMDGEIRRLEKKVALGATYAMTQPPE
DLARTGELREKTREMDVAVFVGIVPLISGRNADFLHNEVPGFEIPTEVRRRIHTADDPEA
EGVDIAREYVDMALDAGFRHIYIMPMLRRYEMAYALVDYIREREGTLPCPD
>A0A1B8Q1I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella osloensis|TrEMBL
MTTPFSFEFFPTKTDDGQTKLLATFDELNALKPQYFSVTYGAGGSTRERTLGIVKALSEK
SDTPITPHLSCIGDDKAKIGELLDYYKSLGINRLVALRGDLPSGMVGLGELPFAVDLVKY
IREHSGNYFRIKVAAYPEMHPQAKSFEADIQNLLNKYHAGATEAITQFFYNADSYLYLRD
ALAKKGVTQDEFPIIAGIMPITNASNLIRFADGCGADIPRFIRKQLADYGDDKKAIRQFG
FEVMINLCERLIAEGVPSMHFYSMNQVSPNKQLIEALGLV
>A0A5C8HZ57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hatanonis|TrEMBL
MTGKDIPGLQEAQSTIPAGTKINVTFLGNEDLEMRVAASKAVVDMGFVPVPHISARRLSS
QAQLEEYLDRLQQVGASSSVFSVGGDPAEPEGPYPDSLSVIRTGLLQKYGATEVSIAGYP
EGHPDIPNDVLWKHLEDKSAALKEQGLDAVILTQFAFDTDPVTTWVNGVRERGITSEIRI
GTPGPAGIKRLIGFARRFGVGANAMIVKKYGFSLTNLMGTAGPDKFVTDLAAELAQNPAS
GDVKLHFYTFGGLKATSEWARDYIAARV
>A0A0R3G371|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides sp. H002|TrEMBL
MTTNPLDHDASVAELQDPGSIADRLAGVQPGDVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDLE
RDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEEQLLRAAGDGPEEDRDEVRKVGVEVATSMAARLVAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A177XYR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio bivalvicida|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELIQIADDYWANGIQSIVALRGD
IPPGGGKPDMYASDLVTLLKERHNFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A6I7EBR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGSLLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEERSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2C0CSC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADIIQTN
TYGANEAKLRMYGLENQIVQINKAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPFHMTEAFKMISIPQDGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIAGMKRAIANIAPVIAKETIPRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDSRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQQLIDTAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A168CW64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAVGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A261TLA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella genomosp. 4|TrEMBL
MTGPSTAALSLEFFPPRDIAAQERLVRAAKQLLAIQPRYVSVTFGAGGSTRAGTADTVRM
LQNLGCDAAPHLSCIGATRDDLRGILSAYREQGVRRLVALRGDLPSGMGGDAGELRYAAD
LVAFIRAETGDAFHIEVAAYPEMHPQAASPQADLNHFVAKVNAGADAAITQYFFNSDAYF
DFVDRAQAKGVTIPIVPGIMPITNHTQLVRFSEMCGAEIPRWIRLRLAEFGDDKASIRAF
GVDVVGALCQTLLDNGAPGLHFYTLNQAEAALGIWRELDLTGAR
>A0A3R7HMM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia fungorum|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFAHKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCQRLIGANVPGLHFYTLNGAAATKAICERLGA
>A0A2M7EY16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium CG17_big_fil_post_rev_8_21_14_2_50_63_15|TrEMBL
MKKPRISFEFFPPKTLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRELTREAVSALHK
ATGLNVAAHLTCVDASRDETLAIAEQFALAGVSEIVALRGDPPKDAGGFVPHPDGFATSC
ELISALAETGKFTIRVGAYPEKHPEAADQKADIDWLKRKIDAGASEAITQFFFEAETFFR
FRDACADAGISAAIIPGVLPIENWSGARKFALSCGAKVPGWLDDAFDKALRDNRHDLLAT
ALATELCSELIEGGVEDLHFYTLNRPDLTRDICHALGVMPKVTLRDVA
>A0A3P5XY82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter ulcerisalmonis|TrEMBL
MSPSSLIEAQPNPADAAPVALSYELFPPRSAAAADTLWTTIRELETTSPDYVSVTYGASG
TNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAVIIGELLDTGVRGILALRGDLPKD
GIGAPSGSLRYAQDLVELIRRVEQRRSALLCAGKVAVGVAAYPTLHPESPTEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLLTRSRRAGVTIPIIPGVMPLISIKRLRRLAELTGVE
PDPHLLSRLGAADTEGERRRIGVNATVDLANAALAAGAPGIHLYTFNEHQNALEVLDKLA
LPRHNRVPVRRGPAAARQLAS
>A0A3S2I9X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.002.02.1.1|TrEMBL
LWETVTRLEPLKPKFVSVTYGAGGSTRERTARTVKRILTETGIPAAAHLTCVGATRDEVD
AVIQDYKSIGINRFVALRGDPASGVGEPYRPHPGGYENGAELVAGLKTIADFDISVAAYP
EKHPQSPDFATDIEMLKRKVDNGATRAITQFFFDNDLYERYVERVRRAGIYIPIVPGIQP
VHSFKQVANFSARAGAHVPGWLAERFEGLDKDPQTHALVASAVAAEQVMDLVERGVGDFH
FYTMNRADLVFAICHMIGIRSHEAAAAGSAAA
>A0A1H2TDU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora shandongensis|TrEMBL
MDANAELLEQYLMNARFEVLPLRGAVEQAELLPAGTTVTVTASPSKGTEATLDVAAQLVG
RGLRAVPHLAARLIADTAHLTALLDRADGLGLSEVFVVAGDSPEPRGGFPDALALLRAMD
ELGRRPARVGITGYPERHAFISDASTIRAMAEKSRYADYVVSQICYDPHTVAAWMTAVRA
RGLALPIHIGVPGVVDAHRLLRISLKIGLGESMRFLRKQHGVVSKLLTRYTPEELLGELS
PYLADPSLGIAGWHFFTFNEIAKTLQWRHDLVARLREVPA
>A0A2S7X9Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliivibrio sifiae|TrEMBL
MAYSHASHLESLNQNIAELDGNINVSFEFFPPSSEKMEETLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLIAAPHLTCIDASRSELVDIANDYWANGIKDIVALRGD
IPAGGGVPDMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQASRFAKMNNVKIPGWMAQQFE
GLDDDPVTRQMVGASHAIDMTRILSREGVKDFHFYTLNRAEHTYALCHTLGVRPKG
>A0A524HED8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
KAGANFIQTQLVYDVKEFAIYMEKVREMGLHKETYILAGVGPLKSPGMAKYMKNNVPGIL
VPDEVIDRMTNAGKEWADKKPSDLSLEEKKARAEAWQTEGIQVCIDLIKDIQKIEGVAGV
HLMAIEWEEAVKPIVEGAGLYPRPEVK
>A0A5M9JZ19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monilinia fructicola|TrEMBL
MLAESERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAQLTCE
MVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEKWEATE
GGFQYAKDLVRYIRQSYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATFIVTQM
FYDVDNFIDWLGKVKARGVSVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSTALEEVKN
DDAAVRNIGKDLVAEMCRRIIEAGVHHLHFYTMNLAQATRMVLEELRLTPSTHRPLKHAL
PWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYGIGL
KGSNEQNIKLWGQPKSIKDIAELFVSYLENGIESLPWSEAPISSEADVIKSDLIELNRRG
FLTINSQPAVDGAKSSDPVYGWGPNNGYVYQKAYLELLVAPDMMPELVRRIQHDPDLTYY
AVKKTGDVQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDWAHCHS
PLSPSRGLIESIMESWYLVNIVHNDFHKSHGLFPLFDGLTVKNLDEPFEISESGDVDGVR
SIEPQTVPLTNGQANGQTSTSLAFKKDLNDPKWNGWGLKSDDRGFDRYTNF
>A0A6M8J3D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eggerthellaceae bacterium zg-1050|TrEMBL
MKIREVFQGRCPVSFEVFPPKGELTLNTATDLIGQIATCDPAFVSVTYSAGGSGNSHLTA
QIAHIAQERFGLNAIAHLTCMGATHNSIAAHIARMRELKVENVLALRGDPVPGSSTGDFT
LARDLIPTLREAGFCVGAAAYPEGHIDCLNEFDNVHHLRQKQDAGAEFFITQLFFDNRFA
YRFLDLAHAAGVTAPISFGVMPFLSKSQATRMVFMCGASLPAPLVKLLARYEHDPASLRQ
AGIEYACNQIDDLVRHGVDGVHVYTMNRPDIAQAAATVARGRA
>A0A7C3G0G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MDADNYVAISGNDSIPVTRLLEPVRIRERVNSRIRQRANKLREAILDPETFCVTWEQIPG
RGALELQQDELINNARKAAKSGKIHGISVTDNPGGNPALSTGMLCTEIKKLGIEPLVHLA
SRDKNRSEIESVLHGLTASQVRNLLILTGDFPANEAFMGRSKPVFDLDPINVLQLIEVLN
NGLEHQVMRKKRTLAPTDFFAGACVSPFKKTEAEQMGQYYKLKKKIAAGANFIIPQVGYD
ARKLHELLTWLKTNGYDMPVLANIYVLPLGAARLMNSNGIPGCVVTDKLVNELTEEAKAE
DKGRSARLLRAAKMYAIARGMGCAGAHIGGNVTYKNVEYIISKGDELAANWKELVAEFDY
PLKDGFYFFKRDSKSGLNTIEPSPRPLKPRVPMIYRFSRLAHKVLFNPNSIILKAFRLIA
PAIDSSPRMKKGFGYFEHLAKVALFGCMNCGDCALTDVAYLCPMSQCPKNQRNAPCGGSY
DGWCEVYPNEKKCVWVKAYERLKPYGEEDQIGENIVPPCNWELWDTPSWLNFSLGRDHSS
KKVGILPPVKKKKAS
>A0A8C8EJK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
MVNQVQRVEDTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGFVFQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRN
YGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVNR
RGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEQTA
EQPNDEQSDKEQPGK
>J9HG00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. OJ82|TrEMBL
MSQLIDKLKNNILVADGAIGTILYSEGLDTCPEAYNLTHPEKVAHIHRSYIEAGADIIQT
NTYGANFEKLKDFGLEHKVKEIHQSAVKIAKEVAKNDTFILGTVGGFRGVKQEDLGLSAI
QYHTEIQVDTLVESGVDGLLFETYYDLEELTNIIKATKRKHNIPIIAQLTALNTNYLRDG
TEINTALQQVAASGADIVGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSQF
KYSDNAEYFGNVAQKLINEGVRVIGGCCGTTPEHIEFIKSSIANLKPVTQKNVIPITKYT
STSSKSKQSQNLTSKVKQRPTIIVELDTPKHLDTDAFFRNIKKLDDANIDAVTLADNSLA
TVRISNVAAASIIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLLDINEILTITGDPSKI
GNLPGATNVYDVNSKGLTEIASRFNQGINTDGDALKTKTNFNIAGAFDPNVRKLEGAVKR
LEKKLESGMHYFITQPVYSTEKIKEVYEATRHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEEVLEQFEAVKDDKEKSKELSLKLSKELIDTVHEYFNGLYLITPFQKADYTLELAAY
SKSITSTKQEAIL
>A0A7V0U227|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MGEVFKKSLLDRELSVTWELVPGRGAVEKGQEELVRSAEAAAKCGKIHALTITDNPGGNP
AISAEFLGVEVNKLGIEPLVHFTCKDKSRNEIENLLYGLERAGINNLLVMTGDYPVSGYK
GRSRPVFDIDPIHTLQMITDMNNGFEYPGMKPGSTVKLQPAHFFAGAAVSPFKRLESEQM
VQYYKLKKKVEGGAQFIITQLGYDVRKIHEVLQIKKKYGFNIPFIGNIYILPFGAAKIMS
KNMIPGCVVTQELVKVLDGERQAEDKGKEARLLRGAQMYAFMKGMGFNGVHIGGHGMKVD
DALFIIEKGEELFPNWQDEVAKFDFPQKGGFYYFTKDEKTGLNTDQEAPRTSRPVVPMNY
KFSRLMHNVCFEPKGALFGLMRGMSKSADKGGFFRFMEHMSKVALFECMDCGDCALTDVA
YVCPMSQCPKNQRNGACGGSFEGWCEVYPNKKQCVWVQAYDRLKNYNEEGKIEKNMVPPP
NWDFFHTSSWANYFLGRDHSAKKAGIQPPPQQD
>A0A6I4Z9N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSFREAMARGEFPVSLEITPPRESKPAVLLRRARLLEACTTTVNVIQRPERQSSLEAALD
LQREGLEPIWHLATGGRPIEEVTADIARAHQAGLGHVLCLRGDHAADTPGTRVTDAIAVV
REQAPGMAIGAALDQYRADERSDRILAGKLRAGARSIWTQPVFELAPLLRSAGFVKAVEP
EANVVAMAMPLLTPESLDAISERLGIPAPAELRRRIEAGEEEAWGAFEETLATLARVELV
DAVAIMTYRADPPPGTAERIVAALQRAGIGEAAGAATDR
>A0A2I0NFR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon HGW-Methanoperedenaceae-1|TrEMBL
METLGSGKFIVTAEVSPPKGTDTTQMLRNAALLDGVADAINVTDNQCAVMRMSPLAACSI
LRSKGYETIMHMTCRDRNRLALQSELLGASSLGINSILVMSGDHPVKGDHKGAKPVYDLD
SVQLLELVRELNRGYDFSGNTLEGKTRIFAGAVTNTELSEVALIKFRKKISSGIHFIQTQ
AVFDTNSFSGFMEQVYSIRSKYNPDVKIIAGIIPLKSVKSADFLNSNIAGIRVPDEIISR
MQNAANPEKEGMEIAAGLISELRGLCDGVHIMPVGNHENTAKIIEMAGI
>A0A1G1JSU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica bacterium RIFCSPLOWO2_01_FULL_45_10|TrEMBL
MTFCEKIKQGKFLITSEIGPPKGIDLKETLEDAELIKNRVDAINVTDLQSSVMRIGSLAV
CRLLKERGIEAIFQLTCRDRNRLALQSDLLSAAALGIENALLLTGDYPTLGDHPEAKPVF
DLGSVQLIEVARTLQEGKDMKGNPLKGTPKFCIGAVVNPGADPLEPEIIKMSLKVKAGAQ
FFQTQAVYEVEKFKLFLEEMKKNDIKTTVMAGIVLLKSAGMAKFMNKNVAGVYVPDNLIK
EMEETKDKSKESIEIAARLIKELKPLCRGIHIMPIGWDKKVPLVLDAAGL
>R6JS10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium clostridioforme CAG:132|TrEMBL
MKTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTREDVLLILEQLKEQKIENILALRGDRVPDREPAGDF
RYASDLVEFIKLHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFRERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFISVMERYGDNPIAM
RDAGIAYAVDQIVDLAAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>A0A369YIW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus sputorum|TrEMBL
MSYAREINILNQSVADLNGQINVSFEFFPPKNEKMENLLWDSIHRLKTLHPKFVSVTYGA
NSGERERTHSVVKRIQAETGITATPHLTGIDATPDELREIAKDYWNNGIRSIVALRGDEP
AGYAKQPFYASDLVTLLKEVADFDISVAAYPEVHPDAKSAQADLLNLKRKIDAGANRAIT
QFFFDVDSYLRFRDRCATIGIEAEIVPGILPVSNFKQLQKMAKITNVKIPAWMGKMYEGL
DDDQTTRNLVAASIAMDMVKVLSKEGVKDFHFYTLNRSELTYAICHVLGIRP
>A0A1F8ZU00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_43_22|TrEMBL
MVSSFSKALQSGRFVVTSEVAPPKGTDLEKMIHHIELLRDKVDAVNITDHQSSVMRFPSL
GGALMVKELGGEPILQMTCRDRNRMALEADLLFAASRGINNVLCLTGDSIILGDHKEAKA
VFDLDSSQLLAAIRQMEKGLDLGGNKLEGTVSFCAGAIVTPEANPIEPQLLKFEKKIEAG
AEFIQTQAVYDLDNFKKFMNYARQFPVKILAGIILLTSAPMARFMNKNVAGVNVPQDLID
EMASAPKGRAIEKGIEIAGRMIKRLHDEKMCDGVHIMAIGREELVPDIMSKAGLI
>A0A0D1C304|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. SPG23|TrEMBL
MSPPSLIDTHPNLSDAAPVALSYELFPPRSPAAAESLWTTIGELEATDPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPEELSEIIGELLDVGVRGILALRGDRPKD
GAAPVSGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPTEAHDVEVLL
AKQRSGADFAITQVFFHTEQFADLITRARRAGVTIPIIPGVMPLTSVRRLNRLAELTGVE
PAPELMARLAAADTDAERRLIGVRATVDLANAALDAGAPGIHLYTFNEHACALEVLDKMA
LPRPARPASRLNAIARRHQEMAS
>A0A523U921|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTNLEKVLESGRFAVTAEAGPPRGAVPSVILRKGELLKAFCDALNVTDNQTAIVRMS
SLSSCVLLKQLGVDPVMQMVCRDRNRIAIQSDVLGAVALGIWNILCLTGDYQSFGDHPTA
KSVFDLDSIQLIQVLSQMRDEKKFLSGEKISGEVPLFIGAVENPYADPFEYRVLRLAKKV
KAGADFIQTQAVFDVSKFAKWMEMVTDRGLDKEVHVLAGVIPIRSVGMARHMRDNVPGVS
VPDEVVTRMEDAKDAREEGLKICLEIIEQIKEIPGVHGIHIMAVAWEEIVPTIVERAGLL
PRPLI
>A0A351JZU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MANSLFEEKLQSNEFLVTTEIGPPKGADISEMVHHIDLLKDKVDAINITDHQSSVMRFPS
LGGCLLVKERGGEPILQMTCRDRNRLALQADLLLAYSRGIVNVLCLTGDSVDAGDHEEAK
PVFDLDSVQLLKMIRIMESGTDIAGKELKGAPNFCIGATVHPEADFIEPQLIKFEKKVSA
GAQFFQTQGIFDLGSLRRFMQYASQFNVRILAGIIVLASARMGRYMNDNVPGIIVAQAII
DELASAGKGKGLQKGIEVAARLIRTIKEENLCHGVHVMAVGNEGIVPDILEAAELVGVHF
>A0A1F9A099|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_43_22|TrEMBL
MKAKTPSKLEKILASGNMAVTSECGPPRGSDPEGIIRKAEMIKNHVDAINITDNQTSMTR
LCSLAACIRLKLMGLEPVLQMVTRDRNRIAIQSDILGAASFDIHNMLCLSGDHQNFGDCA
QGQNVHDIDSMQLIQTVRYMRDEGKFLGGDAIQRPPQMFVGAAANPFADPYEIRVPRLAK
KVAAGAEFIQTQCIYNLDKFEDWLSKARDRGLTEQVYILAGLTPMKSAGMARYMKNRVPG
MDVPEAIVKRLADTPKEKQAEEGIKICIESIQRLKEAKGLAGFHIMAIEWEEMVPEIVEQ
GGLYPRPNVD
>A0A2D5I2G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MELSVEFFPPRTGEGVSRFKNSAKKLSKLGLNFASVTYGAGGSTKDGTLAIARELKSFFK
EGVPHISCYGSKKKSLFELLKLYDSEGFSRLVVLRGDLPSGFGGSGEFKNAVDLVRFIRK
EFGNKFKLEVAAYPEKHPQASSFLEDIQHFVEKVNAGADGAITQYFYNADSYFQFVNEVK
NRGVTKPIVPGIMPITNFKQLARFSDSCGAEIPRWIKEMLKDFGDDREKIYQFGIEIVSK
LCQQLINSGSPGLHFYSMNQAQPIIDIVSKIDLKK
>A0A1Q7C3G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_2_20CM_2_71_6|TrEMBL
MALGLPSVMPGGQQSISELVGAPAPTFSFEFFPPRDDAMERQLWQAIRELEPLRPSFVSI
TYGAGGSTRDNTVAVTERVATETTLLAMAHLTAVNHSVAELRHVIGRFAAAGIRNILAIR
GDPPGSDPQAEWVRHSQGVRYAEDLVRLVKDSGDFCVGVAAFPYKHPRSPSIESDTEHFV
RKCRAGADFAVTQMFFDADEYLRLRDRVVAAGCDTPIVAGVMPVTSVGTIARSEQLSGAP
FPARLAAQFERVADDPAAVRRLGIEQCSGMCERLLAEGVPGIHFITLNRSTATREVWQQL
ALGART
>A0A2N3HRW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labilibaculum filiforme|TrEMBL
MKVIEQLNQAIENKTTHFSFELLPPLRGNSIYKVFNTIDKLKEFDPKYINITAHRDEMVF
TEAADGTIEKKITRKRPGTVAVAAAIKNEYKITVVPHVICSGFSPEETENALLDLNFLDI
HDVLLLRGDSSSRHDFISNEGEHKYAIDLINQVNKMNQGEFLDGTHVDPFVTPFSFGSAG
YPEKHEEAPNLDSDIYWLKKKVDAGADYIVTQMFFDNQKFFNFVKKARAAGITVPIVPGI
KPISALSQLSVLPQIFKTDIPEALAAEVRKCKTNDAVKQVGVEWGIQQGKELIQHGVPSL
HFYTLMASDCVKEIAKAIY
>A0A523QCA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSLQPLFDKGKFVITAEVGPLKGTDTTELMEAVEILKGKVDAANVTDQQSSVMRLGSLAV
CHLLKMKGLEPVFQVTCRDRNRLALQSDLLSAAVLGIENVLSITGDLPVLGDHPEAKPVY
DLDSVHLLWVMKKLSEGYDMQGNELKGKPSFFPGAVVNPGADTEAARELQLIKMEKKIEA
GARFFQTQAVYDPDAFAKFMKRAGKFGVPILAGIIPLKSAGMARFMNKNVSGVFVPDELI
EKMTAAEDKTRMGVEIAADLVKELKGMCQGVHIMAIGWEKKVPLVLEAAGI
>I4M2V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis 1500E|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGIDAVAHLTARYLNYDAVDEALEMFSNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VSYIRSKHPDLPILGACYPEKHPEAESLQADIENLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVQRMTSLCASRITSQVSAMMDRWGSNAECLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWSNVKPLFTKIG
>A0A2E9LMD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MVKITEGCFEATGHTSIICDFSPPRSGDPAAVDQSQIDADFISVAYNPGRTVRTNSAMLA
AAIQRNGKDSMFTLATRDMNKLAMQSQLLGAQMLGLQNVVVVQGDPFGENDQSRVASVND
YQPTELISAIAQMNQGQDFRDGNLRTPTDFCIGAAVDLGKPIEDEVKLAVQKVRAGAEFL
ITQPIFNVDHVARYRESYGYHADQAGTHPVYFGLQILQKDGVVFSSVPDTVRDELEKGRS
GVDIALELYKKFQGARLNNIYLMPPIKRGGARDYEAAKEFLQKAKRI
>A0A1F8YBP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium GWC2_42_11|TrEMBL
MLTLRDALTSNRFVITAEICPPKGTDTTAFIKNAQLLKNRIAAANVTDNQRAVMRLSSLA
CSVLLLKEGIDPVFQMTCRDRNRIALQSDILGAWTLGISNILALSGDHVSFGDHREAKPV
FDLDSVQLVQTISKLNNARNMNDTSLNSGTDFLIGAVVAPEANPLEPEMIKFEKKVLAGA
RFFQTQAFYDMENFKRFYEYAKRFDVKILAGILLLKSAKMAHFLNKNVPGVTVPTNIIEE
LESAPDQLEKGIEIAARQIRELKTFCDGAHIMAIGQEENVPKIIESAN
>A0A3M0HXQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces shenzhenensis|TrEMBL
MALGIPSTRPDRAATIRELLASGHRSYSFEFMPPRSAEAEAGLWTAIRRLEALSPTFVSV
TYGAGGSTRGRTVNVTGRIAQETTLTPVAHLTAVDHSVAELRNILGHYADQGVRNILALR
GDPPGDPLGPWIKHPEGIEYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWESEIRHFVD
KCRAGADYAITQMFFDAETYLRLRDRVADAGCATPIIPEIMPVTTIRSLRRIPSLSTAAF
PPRLAERMLAVEDNPKAVRALGVEHATEMCRRLLEEEAPGLHFMTMNYSRVTTEIYRTLG
LQPC
>A0A2E8URY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MLNTLEIVPKQYEKIFSLPKNMFGDVYVAFIPGDQIDNIISSCKQLVNKGYSVIPHLPAR
NIKNEKELEYYLLQLNKLNIKKILAIGGSSIEKNPTFSSTYELFKTDIFENFDFDQINIA
GHPEGNPFDKNSDENLKEKLNWLVNKNYKCNIVTQWTFDPKRANIWLEKINKDISNISNN
IEIHMGIAGPAKFTTLLRYAKVCGVSASAIIAKNKGLSLTKLLKHNPKEIIKSIVGYDNL
HFFPFGGINELVEWKKN
>A0A2N5Y545|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineobactrum sediminis|TrEMBL
MSTISFEYFPPKTAEGKAALLDKTTPALLDLNPGFFSVTYGAGGSTRDSTFGVVAALCER
GIEVAPHLSFGGDDADTMAALLQRYRDLGVKRLVALRGDMPSGTGGPGQLVYANELVAFI
RQHTGDHFHIEVAAYPEIHPQAESYASDLHYLKLKLDAGADSAITQYFYNVESYFYFLDQ
CAAIGIDKPIYAGIMPITNFANLARFSRNCGAEIPRWICQRIEGYGKDDESIRKFGIEVV
TQLCQTLLENGAPGLHFYTMNQVDPTRQIYQNLGL
>A0A352NXT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp|TrEMBL
MKISEIMKQRMIFSFEVFPPKKDQPMDYLLDTLKHLYVFNPDFISCTYGAGGTNAGRNIE
VCRAIKKSGRTVPVAHFTCIGNSMENIRKSLQIYLNMGIDHVLALRGDFPKGWKGTMGDF
NYANELVAFIRKNFPEFCIAVAGNPEKHFQADSFEEDIAHLRVKQDSGADYIMTQLCHDV
DQYEWWVEKIRKAGISLPIDVGIMPALSKDSIIRMTVSNGSSIPRELAEIIARYGDNPED
FKKAGKEYTIKQMYRFIDAGINGLHIYSLNRWKDVSDILNESGIMGFK
>A0A4R2V915|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PP-CC-3G-465|TrEMBL
MSGFPNASGDLLPGHSSRGRLEQVLRRGEFAVTAELNPPDSADPEEVYARAAVFEGWVDG
INAVDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQGDVLGAAAMGVANILC
LTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDHAKFLSGRKLTAPPRVFLGAAINPFA
PPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFRAYMEKVRDLGLHEHCHILVGVGPMASA
RTARWIRSNVPGVHIPDAIIARLEGAADQKKEGKQICIDIINEVKEIKGVSGIHVMAYRQ
EEYVAEIVHESGVLKGRRPWRREQDPADAGVAERLDAARGGEMQDQESLAETAAKRPH
>A0A241WIF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 3832|TrEMBL
MTKRVPISFEFFPTKTDVGAEKLRVVHQELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDSKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYASDLVA
FIRQHSGDHFHIEVAAYPEMHPQADSFDKDIQNFINKVRAGADAAITQFFFNPDAYFYFV
DRLQKEGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNHTEPNRQLVLDLGLA
>A0A2E2VK32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIKDILNNTRTISCEFFPPRTEEGIPDVFSAAXRLKAYKPDFVSVTYGAGGSTRAFTER
ITSELKEQSELEVMAHLTCVGQSKEEIHSVLERLDQTGIENIIALRGDPPRGETDFVPTP
GGFQHATELIEHIQGNFQMGVAAACYPEGHTESPNLNSDLEYVKQKVDKGAEFLITQLFF
DNNDFFEFLNRAKSAGIDVPIIPGLLPILSAPQIRRFSTMCGASIPADLDRQLDKFADDD
QGARALGIEHATKQVEELWDSGVPGIHFYVLNRSYSVSKILDNLSLQGRNGLG
>R9KFP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium A2|TrEMBL
MKISELLQTKEVTISCELFPPKKGSELKKAHEIVKEMAKVKPSFMSVTYGASGGISEHTV
DLANEVQNVNGVLALAHLTCASSSRDKIQEVLKELEEHQIENILALRGDIPEHLEFPLPD
QYHHASELIEEIRNFGDFCIGGACYPEGHPEAESIEMDIDNLKRKVDAGCEFLTTQMFFD
NNILYNFLYRALKKRIEVPIIAGIMPVTNVNQIKRITSLSGTILPQRFRAIVERFADYPA
ALKQAGIAYATEQIIDLVANGVNHVHIYTMNKPDVAGAIFQNLSEIYKLPEQKRTQP
>A0A3L7JZN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falsibacillus albus|TrEMBL
MKPFLEALEERILIADGAMGTLLYSYGVDRCFEELNLSHPNEVLKVHKDYLDAGAEIIQT
NTYGANYEKLSRYGLEESVKDINTKAVQLAKEAVDGRAYVLGTIGGIRGINQSLSLEEIK
RNFREQLYCLLLEGVDGLLFETFYDLEELKTVVKIAKKEAGLPVVAQVSVHEPGVLQDGT
KVRDALKQLELAGADVVGVNCRLGPYHMIQTLAEVPIPANAYLSVYPNASLPNYEEGRFY
YSAEPEYFGKMSNELRLQGARIIGGCCGTTPDHIRSVAKHLTDRSPILTKEVKVKKEVEL
QPITSRSTPLHEKVKNERTVIVELDPPKHLDTSLFFEGVKALGESGIDALTLADNPLASP
RISNGAIAAIAKERYEVNPLVHITCRDRNLIGLQSHLMGLHTLGVHDILAITGDPAKIGD
FPGAASVYDLSSIELIKLIKQNNEGISFSGKSLRERTQFSVGAAFNPNFRHLDASIKRLE
RKVHAGADYFISQPIYGEEQLQQIYEGTRHLNAPIFIGIMPLTSARNAEFLHHEVPGITI
PESTRRRMEFAGSDPMKARKEGMDIARSLIDTALALFNGIYLITPFTRYDMSIELVEYIK
AQTNEERKVSHGQHII
>A0A424YIM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Syntrophonatronum acetioxidans|TrEMBL
MLKLSKESNLKRVLDSGQFALTGELGPMMGTNLEECLEHAEHNRNHVDAFNITDNQTAVV
RIPSLVTAIRLRDRGIDPVMQMTVRDRNRIMLQADILGAGACGVKNILCIQGDHQTLGSE
PQARGVYDLDSTQLMHCIKTMRDENKFISGGDLEAPLENVFIGGVVNPFADPFEYRVDRF
EKKINAGVQFVQTQCIYDMDRLKEYMKRVVDRGLHERCYIMAGITPLKAIGAAMYMKNSV
AGIIIPDEIVKRLKGAKEKPGGIKEEGLKIAVEQIQQCMEIEGFSGAHIMAIAWEEKVPE
IVERVGGLLPRPKFDD
>A0A5N6S9K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium tibiigranuli|TrEMBL
MHAPMFSLEVFPPRHNAPVGAIYDTLDGLQGVDPDFISVTYGHGSHKDHTATARIARTIH
QEYHIPVVAHLTALYSDAAMIDNALDMFEQAGVSAVLALRGDYIDGEQPVGQFEHASDLV
AYIREHKPDLTVFAACYPEGHIQAASLDEDIEHLKVKVEAGATHLITQLFYDNDDFYHFV
DKARSAGIDVPIEAGIMPIGGPKSVRSSAARNGSRVPERVETMLNRWGDDAATLREAGVN
YASEQITDLVAHGVDGIHLYTMNHPGRTRAIWRNIQPLFTKVPSIAPVSSVSSAA
>A0A143WP57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tremblaya princeps|TrEMBL
MPGLSFEFFAPRSHAGSIRLMCAQQVLSRFVPRFVSMTRSASIGQQAHIDTIASTLSVFP
RTAPHVLFCQCPRALARELRAYELLGIRHLVLLRGDNGIVPGYLGAPELVSLVRRSYGEA
FYIDVAAYPDGHPMSSTIFDDVRALARKVRCGANSAITQCFYNPDSYYRMQDELQRLGVS
LPVTPGIMPVLSHDYMSRFILPSGVDVPAWILKRLEALRYCSASVLEFGTDVALSLCESL
AARGASDFHLYTMNDHRAVWRVCEHLLGSADACHRSCA
>A0A345WLS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. FARSPH|TrEMBL
MTISVNQLEEAQIALKAPLYADVAGDLDVSFEFFPPKTEKMDAQLWEAIRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATREEIDQVARGYWAAGVRHIVA
LRGDPPAAGTRFQSHPGGYENAAALVAGLKRLHPFEISVAAYPESHPDSPDPAADLDNLK
RKIDAGATRAITQFFFEPETFFRYRDAVAAAGITAEIVPGIMPVANFASVQRMSAMCGTD
VPAWMARLFEGLDDHPAARQLVAATLAAELSRKLYAGGVTALHFYTLNRAELAFAICHLL
GVRAKDRAVEAAA
>A0A4R4FM07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pyrrocinia|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTDLCRRLIDAGVPGLHFYTLNAATATRTICERLGV
>A0A2P4X5X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora palmivora var. palmivora|TrEMBL
MGLALQPTFVTLTWRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEELKRVLKNAR
AAGIRNILALRGDPPIGAERWAPVEGGLSNAVDLIKLIREEHGDYFCIACAGYAEVHTES
WNHPDLPPSNEARALDLQRLKAKQDAGADFIITQFFFDVDNMIQWITDCKDAGITIPILP
GYLPIQNYSSFCKFTSWCKTRVPENVLTDLDAIKNDDAAVRRYGTQLAVETCERLLAAGV
NSLHFYTMNLAATVTQVLEGLQLLPARNQRDLPWQSTLHRSTVEGEQVRPIFWSNRQASY
IARTAAWDEFPNGRWGDRTSPAYGELSEYYLAFKRPKLQRAELWGTPQSEEDVWNVFVRF
IDGHVKQLPWCEQSLSLESAAIRENLQWLNSNGFLTINSQPRVNGAPSSDPSVGWGGDNG
IVFQKAYVEFFVAPEKMAHLVKVMRRDYPQLSFHALNRQGDEHRNTPLH
>Q1R0K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11)|TrEMBL
MSTREHPLGVSFEFFPPSTEAGREKLKGVRDTLAERRPRFFSVTYGAGGSTQARTFETVQ
TVRQSGIDTAPHLSCIGSDKGELRERLASFREAGIDSLVALRGDLPSGMGGMGELRYANE
LVEFIREETGDHFQIAVAAYPEAHPQAPSYEHDLQNFVRKMQAGADLAITQYFFSADAYF
HFVERARALGVEAPIVPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIQAF
GSEVVTRLCQRLLDGGAPGLHFYTLNQATPALRVLDNLRCDT
>A0A4Q2YZK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium|TrEMBL
MTSNLNSLAEARRAAASPLFANLEGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASRAEIDEVAQAYWDAGVRHIVA
LRGDVPGGAPYRAHP
>A0A399D858|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariniphaga sediminis|TrEMBL
MKVIDIIKNSDKTVFSFELLPPLKGNNAGRIYKTIESLVDYDPKYINITTHRDEVEFREL
ADGSIKKRTIRKRPGTVAIAASIQHKYGIPVVPHILCGGFNKSETEYVLIDLNFLGIQNV
LALRGDGLKDQHTFKPEENGHAHANELVEQIVNLGKGQYMEQDLKNNTPLDFCIGVAGYP
EKHFEAPNLEQDLSYLKQKVDAGADYIVTQMFFDNQAYFDFVKKCREIGINVPIIPGIKP
INMKNQLTVLPKIFSIDLPQDLSKELAKCKNNEEAREVGTEWAIYQSKDLVAHNAPSLHI
YTYGISDNVKEIVKAVF
>A0A291GJQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium vulturis|TrEMBL
MSVATTTLPELERTAPVRHRPALSYELFPARSDVSFERLRETITQLEATAPDYVSVTSRT
GHGNLGRVLELTEHVLAETSLRPLVHLTSIGSTRAQLTTIIHALLDRGVRGLLALRGDQP
DGHRLEDDEIPFARPLIELIRDIERERTAGLAGGRVSVGVAAYPHRHPESPTISHDTEVL
VAKERAGADFAITQVFFDPDVYTRCLDRSHAAGVRLPLVPGLVPATNPRRLQRLAAMSGV
EPPRELLHQLELAAEETERRRIGIRFTVDLARRVLDAGAPGLHLFTFNQHAEALDVLDHL
DLDRWSTTSQGDAR
>A0A357X9D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp|TrEMBL
AYPEKHPESASEAVDIDMLKRKADNGATRALTQFFFDNDVFERYMERVTAAGITIPVVPG
IMPIQNLTQLKRFAGRCGTSVPGFLDERFAGYDDDLEGRARVAAEVAAEQIADLQRRGVS
EFHLYTMNRAPLVDAVLENLGLEXXRAPLVDAVLENLGLERLRRSAA
>A0A516SG97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinimonas arctica|TrEMBL
MYTYEPAESAVSQTFSFEFFPPKTEEGIAKLRNTRRQLAQLHPSFFSVTFGAGGTTQEGT
LATVLEIQSEGFEAAPHLSCIGATRSNVAGLLNTYKSHGIDRIVALRGDIPSGMVEFGEF
RYANELVEFIRAEHGDWFHIEVAAYPEYHPQARNAQDDLNNFVRKAKAGADSAMTQYFFN
PDAYFAFVDEVRARGVDIPIVPGIMPINNFTQLARFSDSCGAEIPRWLRLKLQSYGDDSA
SIKALGLDVITDLCRKLLDGGAPGLHFYTLNAAGNVSTIWQRLGL
>A0A671X1A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sparus aurata|TrEMBL
MVNQVQRGDGSWQSCKSDSSGASNSGGESSKESSRCSTPVLDTDRSDRLRDKMRRRMESG
ERWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKDKISGYLGKAKHLGLKNIMALRGDPVGADWEEEEGGFNFAI
DLVKHIRSEFEDYFDICVAGYPTGHPEADSYEEDLRHLKEKVDAGADFVITQLFFRAETF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITEVIEPIKDNDAAIRN
YGIHQAVEMCRVLMDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLQMWGQELMNEESVFEVFTCYITSQPNSSGHKVMCLPWNDEPLAPETNLMKEELEKVNR
RGVLTINSQPNINGKTSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVADPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIINYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPTEPLYSETCQ
NEL
>J0CB41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii WSM2297|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWQTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGISIPIVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFDD
RPEERAKIAADVAAEQIEDLVRRGLDEFHLYTMNRSPLVSAVLDNLGLSRRAAKSAGAAA
>A0A7Y9Z8B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter geojensis|TrEMBL
MTSPRVSFEVFPPRNVDAGFNLWDTAQMLAPLEPRFFSVTYGAGGTTRDLTHDAAHVLRR
TSGLPVAAHLTCVGASKAETLEVADTFAKIGVTDIVALRGDPQDGAKTFTPHPEGFADSC
ALIEALAGKGTFNIRVGAYPDSHPEAADMDANVQWLKRKFEAGADEAITQFFFETDSFLR
FRDACAKAGIDKPITPGILPVLNWKSARNFAKRCGTPVPAWLDDAFEAAIRDDRHDLLAT
ALCTEMCSTLVDEGVEDLHFYTLNRAELTRNVCRALGVTPQVSVRDVA
>A0A4P7SHZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas shaoxiangyii|TrEMBL
MTAVTGTRPPAAAVEAPPRTARRRSEPAAALDRPTVSFELFPPRDLDAAPRLWRTVRELE
AAEPDFVSVTYGASGRTRETTRALVTRLLRETTLNPIAHLTCVGTSREEVATIVEEFLDE
GVRSFLALRGDPPAGQTDWQPHPDGVDTAAGLVALLREIERRRCAGSPAQAVRARVRPLS
VAVAAFPRGNHATGGTREQDVQALLAKQEAGADFAITQVFFDAEAYLGLVAEARRAGVTI
PIVPGIIPTTDPARLERVQELTGVPVPRTLLDLLGSVDDPAERHRRGIRASVDLVNGVLD
GGAPGVHVYTFNRHEAALDLLEGADLRGGPPAPGRAPADRAAPTRPTTSPEPAGDPAAVP
TTTPRGIPS
>A0A1I1RZD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas straminea|TrEMBL
MSQKRPNVSFEFFPTKTDAGHEKLLNTARELAGYNPDFFSCTYGAGGSTRDRTLNTVMQL
DSEVKVPTAPHLSCVGDSKAELVELLNLYKSKGINRIVALRGDLPSGMGMSSGELRHAND
LVELIRAETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADCYF
YFVERVRKLGVDIPVIPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDTQSIQRF
GEEMITGLCERLIEGGAPGLHFYTLNQAAPSLAVWKNLQG
>R7ELQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides uniformis CAG:3|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A1Y6CFL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogulbenkiania subflava DSM 22618|TrEMBL
MSIPFSIELYPPTSPQSAGQLERALPRLAALGPECFSITYGAGGCTRERTLDLVGQLHQA
GHTVAPHLSGVGAERAEVAALCAHYRHLGVRRLFVLRGDTPSGMGSRGDFAYASDLVRFI
RERSGDDFRIEVAAYPEVHPQAKSPAADLAALRAKQEAGADAAVTQYFFNTDAFLYLRDS
CHAAGITLPLVPGVLPLTRFRSTAQRAEARGIEMPRWIYRKMESLADDTAAVRAFGLDVT
ARQCERLIAEGVPALHFFSLNQIDAIETLHARLGLARSAGVTASPPN
>A0A433CR05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp|TrEMBL
MVRSGGEFYRMVGAYATKGDRVGLAQRIAERDDGVLLFSLTPPRASTSPEDAQRIADVTL
ARLEALDVDGLVLYDIDDESDRNPAERPFPYLPTMDPAVFLAENLVSWRRPVVVYRCVGK
YDEESMERWLSEQDAADVLSVFVGASSSVKERALELSAAQKLRAEVNPALQLGGVAIPER
HSRTGSEHHRMVAKQQAGVSFFVTQVVYDVSAAKSMLSDYFYACADAGLAPVPVIFTLSV
CGSMKTVEFLEWLGVDVPPWLRNDLAHADDPLSVSFDQCLATAAELTEFAKRIGTPHGFN
VESVSNRRREIEASVELAARMRS
>A0A7K8BMB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhagologus leucostigma|TrEMBL
MGNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETVLHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A0D6GM48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium diphtheriae|TrEMBL
MSAQPLPAAYQRTITDVISMPTPGQVPFSVEFMPPRDEAAEERLWKAAEAFHDLGASFVS
VTYGAGGSSRERTMRVAHKLSRHPLTTLVHLTLVEHTQEELEEILCTYASHGLSNLLALR
GDPPGTDPMAPWVPTAGGLDYAKDLIDLVRKTEQTSHFQVGIASFPEGHYRAPSIEADTQ
FTLEKLRAGAEFSITQMFFDVDHYLRLRDRLVKADPEHGSKPIIPGLMPITSLRSVRRQM
ELAGATLPKALEKRLLDAARGDEEAHRGDIRKVGIEVTTEMAQRLISEGIPDIHFMTMNY
VRATQEVLHNLGMAPAWGTQQGHDAIR
>A0A847LWR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exilispira sp|TrEMBL
MKITEKLTRGRSISIEIIPPKRGDDCSAIFSMLDRFVKFQLLFVSVTKHLKREILVPYKN
KFLTLKNTNRPGTVGLTQAIMTKYNIDVVPHIVIGNQSIEDVEDMLIDLAFCGIENIFIV
RGDLADNEKKSTANHSFYYHSSEAVQRVRMLNKGQYISVKNGKPIDFCIGVAGYPEKHYE
ALNQYDDLLNLKKKVDAGADYIITQMVFDPVIFKKFVLKARKVGINVPIIPGIKPITNIK
SLFSIPKNFFVTIPHSFTEKIMSAKTTEKQKNIGINYTIELIESLYDQGVPAVHLFTTNM
GEDIYQIMKELSSIVSAKV
>A0A0H2ZKY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa (strain UCBPP-PA14)|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A1L0C1Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] intermedia|TrEMBL
MKISEKLLQAHACANPPPATFSFEFFVPKTSQGVQNLYDRMDKMYDLNPIFIDITWNAGG
RSSSLTNEMVYTAQSALGLETCMHLTCTNMPVSLIDEALEKAYRSGCQNILALRGDPPLD
GSESTGDFKYAKDLIAYIHKKYGNHFNIGIAAYPEGHPEEENGDNLMKYLKEKADAGADF
IITQMFYDVDNFIRWCEQVRKAGIDIPIIPGIMPISTYSAFIRRAKWSQVVVPQHFLDTL
DPIKEDDYAVREAGTELVSEMCQKLIDSGYVNHLHFYTMNLERSTVMVLEKLKLVDSVAD
NDVVAEVLPWRKSLHPMRSKEAIRPIFWQNRKHSYISRTSGWDEFPNGRWGDSRSPAFGD
IDLAASQLLRQSPKRALELWGCPQSLKDFSDIIVSYLKNEIKSLPWSDGPIGTDTNVLKD
ALIEVNKKGFFTLNSQPALSGIRSNDKTFGWGPKNGFVYQKQYLEFLVHKDVAQELLTKV
EEHNKKDQHSVITYYAVGKQGDVETNSKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWK
DEVYSLLDEWVTIFHSKALSESVEKDKVDVFSKLFTSFGDEFVLCNFVNNDFTSDNNVMF
SLLNDLNVPYL
>A0A3Q9TFD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. Arc7-R13|TrEMBL
MTTPNVSFEFFPPKTLEASFKLWETAKVLAPLAPDFVSVTYGSGGTTRKLTHEAVTTINR
QFGLQVAAHLTCVEATRAETMEIVQSYADAGITQIVALRGDAPKGADRFTPHDDGFANSV
ELIEAIAARGDMTIRCGAYPEPHPDSADGDADVTWLKRKIEAGATSAITQFFFEPETFFR
FRDKCVAAGIDAPIIPGLLPVQSWAGTKRFAATCNTTVPDWAEEAFQLAALDGPDAQRAL
ATDLSVDLCEKLIAGGVDQLHFYTLNRPELTRDVCAALGVRPKAGLEAVA
>A0A8J6I2C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capillibacterium thermochitinicola|TrEMBL
MRIKDYYKNKPVFSLEIFPPKPGSPLDGVFATIDALSVLRPDFISVTYGAAGGSRFYTVE
IADTIKNKYGIEALAHLTCINSTKEEVAEILGRLQKAKIENILALRGDRPADQSTIPPTT
DFQYASDLIKFIKTKADFCIGAACYPEVHIEAEDAMADLHNLKRKVETGADFLITQLFLD
NSIFYAFREKLDKLAIGVPVAAGIMPVLNKKQIERITSLCGASIPPKFRRILDRYENSPE
ALKEAGIAYATEQIIDLLSSGVDGIHLYTMNRPEVAKTIFGQISGIRKHLKAET
>A0A7W3A1W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella sp. RHBSTW-00465|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRAIAQDYWDSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7G6VVK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceicoccus marinus|TrEMBL
MSKPLFASLPGDIDVSFEFFPPKNDKSEEQLWDTVLALAPLRPDFVSVTYGAGGSTRDRT
HGTVARIIRETGLPTAAHLTCVDASRDEIREVAEGFWNAGVRHIVALRGDPPTMGDRFVP
HPDGYASAADLVAGLKDIAPFDISVAAYPETHPEAQDPQADIDNLKRKLDAGASRAITQF
FFAPEKFLRFRDLAAAQGIDAPILPGILPVSNVAQTRKFADACGAEIPKWMEELFEGLDN
RPESRKLVAATIAAEMCRSLYAEGVRDFHFYTLNRAELSYAVCHLLGMRPREAALVQENA
A
>A0A5P9CZI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labrenzia sp. THAF82|TrEMBL
MNSVSNRRSHQAAPTPITASFEFFPPKSDKMAETLWNTVQRLAPLHPSFVSVTYGAGGST
RERTHKTVERILKETDLAPAAHLTCVGASQEEIDGIVKDYWDLGVRHLVALRGDPLEGIG
TRYTPHNNGYPYASDLVSGIKKIANFDISVSGYPEKHPESGSWQTEIDNLKRKVDAGADR
IITQYFFDNDVFDAYLDRIAAAGINIPVIPGILPIHNFEQTMVFSAKCGTSIPQWLARRF
AGLSNDPETRKLVGVSVACEQAMDLVDRGINDFHFYTMNRADLTYAICHMLGMGQSEQKG
LAA
>A0A1V6QG92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium antarcticum|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKVLGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVKYIRKTHGDYFCVGVAAYPEGHPVDAFQDTQDPARDIPY
LVEKTVAGADFIMTQLTYDIDAYTKFENMLRNHESGVFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIARRMEELKHDDDAVKRAGVDIVSEIVGGMKDIPSPGPRGFHFYTLNLEK
TVSFILEQSDLIPPYSEADNSAIEEGPPLVDFPGRALGRSRASSMHSQPHNRVIVDKLSV
HESSQDSQHEALAESVGLPMHPNRSTTLLISEGQGSLGREATWDDFPNGRWGDARSPAFG
EIDGYGPSLHVTSAVARRLWGHPVDAKDMSTLFRRHVSGELHMVPWSEGGAEEDGGGLNA
ETELIRPELLKLIDGRGWWTLASQPAVNGVKSDHHIFGWGPQREGFVFQKPFVEFFCSNN
DYKNILKPLFAQHGSDKLTWFATNISGAFESSLPAQPTDVELDSLEDNPESVNAVTWGVF
RGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTETYLDTTKNDAWLVCVVGQQ
FGAGTKQGSKEEEDEVKWMWRVLAGEDA
>A0A2Z3JKP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus irradiatisoli|TrEMBL
MPEAPSTAPKRTRISIELVPRSLTHLRAELQTVAEHFGNVDTVNIPDLLRFKTRSWQACT
HAAGHVQRAIPHIRAIDIDPRKPLPMADHLRQHGISEVLIVSGDPPEGMSSLVYNVTALD
ILRKFRRELPEIKLYAGLDPYRQSFAAERDYAEEKLEAGASGFFTQPFFDLRLMELYAEL
LPDAEIFWGVTTVMSERTLNYWQERNKAVLPRTFEPTLAWNRQLAADALRFSRERGQHIY
YMPVTANLKEYLEGIV
>E9ED23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium acridum (strain CQMa 102)|TrEMBL
MCFKPPSPPLVSLDNSSLSPTTTITTVTNMHIKDMLAEAEKGGQPSFSFEYFPPKTAQGV
QNLYDRIDRMYNFGPKFIDITWGAGGRIAELTCEMVLQAQSVYGLETCMHLTCTDMGLEK
VNDALKKAYKAGCTNILALRGDPPRAQEKWTATEGGFHYARDLVKHIRATYGDHFDIGVA
GYPEGCDDNKDEEQLLDHLKEKVDMGASFIVTQMFYDADNFVRWVGKVRERGINIPILPG
IMPIATYASFLRRAKHMQCKVPDHWMTALEPVKNDDVAVREIGKTLVADMCRKLLANGIY
HLHFYTMNLAQATRMVLEELTWAPCAERPLQQALPWKQSKALGRRDEDVRPIFWRNRNKS
YVLRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEANRKKWGEPTTVQDIASIFVK
YLNREIESLPWSEAPLTGEANAIKDNLIQLNKRGLLTINSQPAVDGVKSSHPIHGWGPSN
GYVYQKAYLELLVPASIFAEMVKRIEDKPTLTYYAVTKDGELKTNAPSDGPNAVTWGVFP
GKEIVQPTIVESISFLAWRDEAFRLGTDWAHCFESETPSRVLLDQIMNEWYLVNVVNNDF
HENQTIFDLFEGLEVKGLDTPVAV
>A0A0Q0BAV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. tomato|TrEMBL
MEVSSPMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLN
TVLQLENEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGEL
RHANDLVAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFN
ADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQ
SIQAFGEDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A2D7MYX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonadaceae bacterium|TrEMBL
MALSLQEKIEDTNQGVYLIGTTPPKIGTDKAQLKIIAEKLLARLHEIEYDGVIIYDIQDE
SSRTDKARPFPFKQTVDPREYSHLLRNLSAPDVITYKSVAQRGVEEFKGWLDETKNDYDL
KNVVLVGSPSSVGDIKLSLPDAYKTLAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGITPKRIILTFTPCGGDKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKQIA
>A0A1L8MFP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. V450|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKSEAMEKTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASREELKQIAQDYWDSGIRRIVALRGDLP
QGVDKTEMYASDLVTLLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DEDDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRCELSYAICHMLGVKGN
>A0A4J1QI59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSCQTPSLSFEVFPPTPAVGNDNIILALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIELIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNEHFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A6G2Q6S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID685|TrEMBL
MALGTASTRTDRARTVRDMLAGGKTTYSFEFSAPKTPKGERNLWTALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVAHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVEAGCDTPVIPEILPVTSVRMLERLPKLSNAQF
PDALKERILAAKDDPAAVRSIGIDFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHHPPQA
>A0A7X1KKC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium flavum|TrEMBL
MISPDHPLFAGLPGDVSVSFEFFPPKNEKMEAQLWDAIGQLAPLDPSFVSVTYGAGGTTR
ERTHATVARLVQETDLIPAAHLTCVGASKGEIAEIADQYWEAGVRRLVALRGDPPPESGG
TFVPHPEGYASAAELVEGLARSHDFDISVAAYPEVHPEAASAEADLDNLKRKLDAGAARA
ITQFFFSTDAYFRFLDKALAAGITAPILPGIMPVTSFAAIRRMSGNTEIPGWMVALFEGL
DERPGPRTLVAAVAAADLCRRLYAGGVRDFHFYTLNKAEQAYTICHLLGLRPKA
>A0A857AAZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schaalia odontolytica|TrEMBL
MPFSDDTYACPCTHDHEPTLLSFEVMPPRRPSLEEPFWNTVDQLLRVRPDFMSVTYGAGG
KDRSNARSTVHRLVRDTPIQPIAHLTCVGNSTEEVVSTVYDYLDSGVRTFLALRGDPPVG
QDGWEPGPGGVGSATELIHLIRTVEKRRCDAHPGEALRSAFKPLTIAVAAFPAGNPAAGT
TPAQEVERLLVKQAAGASFAITQLFWDAEVYASFVERARRAGVTIPIVPGLLPATDPARL
RRVQDLTGIEVPEYLLTTLADYPRQDARDEFGAVFGSRLIHSVLEAGAPGVHLYTFNRSK
PVLDILALMGVKPDPLRSQASSPETRA
>A0A4M3JYA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPYFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYLHQATHALFNHQSLG
>Q46A56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina barkeri (strain Fusaro / DSM 804)|TrEMBL
MLFNFREKLNSSKFLVTAEVSPPKGTKFSVSLEDVRQLKGIADAINVTDNQCSIMHMSSL
AFSKLLLDAGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICVMTGDFPSCGDHPGSKP
VYDLDSVQLLQLVRKLDSGINFTGNRLDGGTSFCAGAVSGIDPEKPLQLIKLEKKVRCGA
DFIQTQAVYDVGMFEEFMEAISHIEVPVIAGLIPLKSLGMAEFMNRNISGVHVPEEIMLR
IKDAPDPVEEGLSIASETIKEITKLSRGVHIMPVGSHKNTARLLSMAGISGK
>A0A660RUN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteria bacterium|TrEMBL
MKDNFAEHLKKKVVLGDGAFGTYLFEKGVDLAKNTDLLNISDPDLVYSIHEEYIRAGSEL
IETNTFGANRFKMLKVGREHRVREINLRGAELACRAAGDEIFVAGSIGPTGVKFPLESDE
TESGTVQEAFVEQMTALLEGGVDLFIIETFTYLDELLLAIEAAKKIAPDIPVVAQMVYPF
NGRTAIGLDALACGRATAAAGATVVGTNCGRGVKAMLSAVERLSSLKDEVFLSAFPNAGL
PEVVEHRMVYSTPPSYMAEKVTEMVKLGVRLIGGCCGTTPDHIREFRKHLRLKRHKAVSV
AAAVEKSSDLPEDRKDSIGRGGMIESLRPGRIPVLVEVDPPRHLDIEGILTGARALVEAG
ADAITLAEHPLAVLRADNLSLAHRIREETGIQTVLHLTCRDRNALGLQAQIMGAHVLGLE
AILAVTGDPATSTDQPGVSGVFDVRSFGLVQMISRFNRGLNMAGASMKKRTNFSIGVAFS
YHPANPDLQISRLERKVDLGAHFAMTQPIFDRDVVESMMEQTQHLDLLIFTGIFPLISAR
NADFLHNEIPGISIPTEVRKHLWKYEKVEDQRKAALDLTRKLIADITPFADGLYLISPLN
KWEIPLTLVKEVRASGH
>A0A6I3UNI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPR
>A0A521AN12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gracilimonas mengyeensis|TrEMBL
MKVNEHIKKANGNTLFSFEVLPPLKGQNIQSLFEHMDPLMEFNPPFVDVTYHREEFVYKK
RENGLLERKTVRKRPGTVGICAAIQNRYEVDAVPHIICGGFTREETENALIDLNFLGIDN
VLLIQGDTRKPEREFVPEPGGHEYASDLIEQVVDLNNGVYLDEDLENAQPSDFCIGVAGY
PEKHFAAPNMETDLKYLKQKVDKGGCYVVTQMFFDNQHYFDFVKKCRALGIDAPIIPGLK
PITSKKQLTILPQIFHVDLPVELTSEVEKCSSREEVRQVGIEWAIAQSKELMEFGVPTLH
FYSMGKSDSVYAIAKELF
>A0A4P7WQ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VHNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVQQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCILADIEVPIIAGIMPIINRNQALRLLKTCENIHLSRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>E2ZDC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera micronuciformis F0359|TrEMBL
MKIIDILKNKRVTLSFEVFPPKTADAVPTALAAAEAIAALHPDFMSVTYGAGGGTSDFTV
HIASAVKKTYGVEVMPHLTCLSSTKEKVTETLQDYKEAGFETIMALRGDVPADGTRKNDF
EHATDLMKQIKSFDSSMALGGACYPEGHPESPSLAADIENIRRKVDAGAQFLSTQMFFDN
SLFYSYLNRLHAAGIDVPVLAGIMPITNKRILTRSLAMSGTAVPARYIAMVDAYGDSPEA
MKQAGIAYATEQILDLYANGVRNVHVFAMNKPDVAKAISENIRPVLDYLNSK
>A0A2S4WCG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia striiformis|TrEMBL
MKISQKLAAAESENRISWSFEYFPPKTDNGLTNLYDRIYRMSQLGPIFIDITWGAGGSTS
NLTTEFVKTAHEQFGLETCMHLTCTNMPKENRYRFERSTEWTATEGGFEHAIDLVRHIRA
GYGDHFDIAVAGFPEGHMHSSLTKEQETIYLKEKIDAGANFIFTQMFYDVDIFIDWVREI
RAAGITVPVIPGLMPIQSWAQFKRVTNFSKTIVPQYFLDTLEPIQSDDQAVREAGTKLVA
DMCRKILNSDLGIRILHFYTMNLERGTKMLLDELNLNPSRDITNPLPWKMSLLGKRRSES
IRPIFWANRAKSYLSRTETWDEFPNGRWGDSRSPAYGELDGYGININSATIETLKGLKKF
PTSLEDLARIFANYCGARFPGEEPVKYLPWSDIALSEETGKIEDVLVKINKRGFLTINSQ
PAVDGAKSSDPVHGWGPRGGYVYQKAYLEFFCCPEKFQSLTERLEQDPDVTYYAVTKTGD
LVTNNTRPGPNAVTWGVFPGKEIVQPTIVELVSFIAWKDEAFELGHQWAELYKDTAPESS
KFIHEIMDSWYLVNIVNNDFRKSNDDSENSALFQFFGPEPVIVKEDGVPSTNGFHHSIGI
SKVNGTRYCQWTQRGHQKPCHLSCKSDV
>W4LLW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Entotheonella factor|TrEMBL
MKIRDMYDRQQPVISFEFFPPKTTGGVTNLFKTVNTLRTYKPAFVSVTYGAGGSTRDKTV
DLVRRIKSEIGIEAMSHLSCVGATKADIDSILDDLAAADIDNILALGGDPPRDQPIVDRS
AWGFQHANELAAHIKTRQRFCIGGACYPEGHIDAPSKDIDLKYCKQKVDDGAEFLITQLF
FDNRDYIDFVERARAIGIEVPIVPGIMPVTNFTQIKRFAGLCGATIPRQMSFDMAPVEED
LDKVEALGIAYATRQCRELLDAGAPGFHFYTLNKSRAMSQILDNLKLG
>A0A0L1LV83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. ZBG10|TrEMBL
MSPPSLIDTHPNLSDAAPVALSYELFPPRSPAAAETLWTTIRELETTSPDYVSVTYGASG
SNRDTAVELINRLVVETTLRPLAHLTCVGNTPQELAAIIGQLLDTGVRGILALRGDLPKD
SGAPIAGSLRYAQDLIELIRRVEQRRSAMLCAGKIAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTAQYADLLTRARRAGVTIPIIPGVMPLTSVRRVTRLGELAGVE
PAPELMARLAAADSDSERRRIGVSATIDLANAALDAGAPGLHIYTFNEHQSALEVLDKLA
LPRHSRNGLLADAK
>A0A086Z0K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium actinocoloniiforme DSM 22766|TrEMBL
MHQPIFSLEVFPPKRDAAVGTIYDTLDGLEELEPDFISVTYGTGRQSDRTATARICRTIR
QGYGISAVAHLTAQYSDEGVVREALDMFEQAGVSAVLLLRGDCVQGRKPAGVFTHACDLI
AYVRRTKPNLRISAACYPETHPEAVSPAEDIRHLKEKVDAGADHLISQLFYDNEDFMRFL
DRAREAGVCVPIEAGIMPITKAAQVRRMSSTCGFRIPPAAERLLDKWGGDTEALQEAGIA
YASQQISDLVAQGADGIHLYSMNQPVVTRRIWRNVRALFAKVPCDQLELGKS
>A0A385BPZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariniflexile sp. TRM1-10|TrEMBL
MLENKINNRKSGVLLYGLTPPKLNTEEHKIKAIADKQIERISVLEIDGLVLYDIQDESSR
NDKPRPFPFMDTLSPEIYNTTYLRELNLPKIIYKSVGKYSVNELNAWINEYAKNIDYSVF
VGTPSNRLKSNLSLNEAYHINKNSVNSIRLGGVIIPERHYKKNDEHIRLFNKIDKGCHFF
ISQCVYNIDNTKNFLSDYYYSSLDNNRELHTIIFTLTPCGSLKTMEFMEWLGIDIPKWLK
NDLKHSKDILLKSIEICKTIAEELLNYCKDKNIPIGFNIESVSIRKAEIDASIELLKEVK
VLMNKYQYSAIVCE
>H8L333|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frateuria aurantia (strain ATCC 33424 / DSM 6220 / KCTC 2777 / LMG 1558 / NBRC 3245 / NCIMB 13370)|TrEMBL
MPAISFEFFPPKTEEQRNQLNLCVKALKTRSPEYVSVTFGAGGSTLNYTEQTVQQLHRQH
GLQVAPHLSCVGGTREELSELLDRYKAIGCRRIVALRGDLPSGMATPGDFRYAVELVDHI
RRHSGDWFHVEVAAYPEIHPQSESAITDLHHFKAKVDAGANGAITQYFYNADAYFRFVDD
VHRLGVDIPIVPGIMPIGNFSQLRRFSEGCGAEIPRWIVRRMQALGDDAEAIRQLGIDIV
ASLGQRLLDGGAPGLHLYTLNRSKPALAILDRLQ
>V9TVQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Endolissoclinum faulkneri L5|TrEMBL
MFNTPNVSFEFFPPKDKEGEANLLRTVSCLEAYRPSFASVTYGAGGSTREGTSRIIKRLA
EESTLTPAAHLTCVGATREEINEIVRAWQAAGIKHIVALRGDAPAGAEKYQPHPNGYANA
AELTAGLRKMGDFEISVGAYPDVHPDSPSVAADLENLKRKIDEGANRAITQYFFEADTFL
RFRDLCTKAGINVPIVPGILPIIKFKTVLHFSKSCGAVIPKWIVDLFDGLDEDPETSQLV
AAATASDLCMKLMTEGVEDFHFYTLNRSQLTSAICRRLGRRPHNAKCNLSNS
>A0A143QRM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus fascians|TrEMBL
MTRTPSIVDRLRTEPEARIPFSVEFSPPRDEAAEARLWRAVREFEQLQPAFVSMTYGAGG
STRDRTVRVTGQIAEETTLLPVAHLTAVSHSVAELRSMVGSYADRGITNILVLRGDPPGD
PLGEWEKHPEGVEYAEELVRMVRELGDFHVGVASFPEGHHRADDLEQDTRCLVGKLRAGA
EYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSVRRMLELSGSTLPSH
LDEKFTRAAGSGAEEDKAAVREVGIELATNIGERLIAEGAPGLHFITLNFARATREVLSN
LGLAAARV
>A0A6P1VJA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechocystis sp. CACIAM 05|TrEMBL
MTISRFRQAAEAKEFLITAEVTPPKGGNPERMLSVAAKLRGRVHGVNVTDGSRAVLRMSS
IAACVLLQQRGIESICQMTCRDRNLIGLQADLMGAYALGLRNVLALTGDPLKAGDHAKAR
PVYDLESVRLLSLIRSLNQGLDFNQAPLVDGKLDLFPGAAVDPQSKSWSGLQSRFERKLT
AGAQFFQSQLITDFDRLDKFMTQVAVGCGKPILAGIFLFKSAKNATFIKRVVPGVNIPDA
LIDRLARAEDPLKEGVAIAAEQVKLAKELCQGVHLMAIKKEELIPEILDQAGIAPLEN
>A0A6I1YIT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. dk4132|TrEMBL
MWRRCRGHRGCVSGEQGCPKRMTFGPCGGVRDDASCELDRRPCPFAQPPAEVVRWPAETA
PPGRSSPPSRLLDAARSGPVVLSDLTTPAYDSAGLAAVVDVLCGSCDAVLVGEHQSRPDF
PPALMSTLVAQAGGTPWVTLTCRDRNRVVLEQELAGLALTGVDGVLCVTGDVRAPGVRSG
VSQVFDLDGTRLAALARERGHAVAVPEAPAAVPRALRPARLLQKQRAGAHLGVLNHVATP
REVADFVAAARALGVTIPVIAAVAVYTDERSARVLQRFPGLHLEDDRVEAVLGAPDVREA
GIEAAVAEARALLAVEGVVGVNLSGLASGEGELAGARVKAEIGERIREGR
>A0A6I2JZD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CAH-1|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVQVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRTETGDHFHLEVAAYPEMHPQARNFEADLGNFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLALWNNLKLPR
>A0A7K2HMM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp. SID5947|TrEMBL
MRVTSSPVRAPSIVDRLSAPHRGPVPFSVEFFPPRDADAEARLWRAVRTFERLGPAFVSM
TYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVDHSIDELRALVGAYADQGITNILALR
GDPPGNPLGEWVQHPEGVAYAEELVRLIDQLGDFHVGVASFPEGHHRAPSLEDDTRTLVN
KLRAGAEYSITQMFFDVEHFLRLRDRLVRADPEQGAKPLIPGIMPITSLASVRRMAELSG
SVIPADVQARFAAAAGDGAEENREAVRAVGIDFATEMAQRLVSEGVPCIHFCSLNFAKAT
SEVLERLGVDTSSALSATVG
>T0MT07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon E-plasma|TrEMBL
MRKESNVVVLLRETLNQRKFVRSFEFVPGKHLGIGDMEKVAEKVSGLVDVVTVPENPLGN
PGIDPILSLYALSEKMDFIGIPHLTPRDKNSLHLKSQGMSALKLGIRNFFVVYGDPIAQG
QNSKEVRELDVVGTIKTLKESRLEFNGTSGSIEMNVGAAANPQRENEIQNIIRKQEAGAD
FFITQAIFDAESMKVQWIKERQHKIVAGFIPLKKKPQIDIMKRMGIRFSETVEKRLDNSD
DIQNESSRIILEIFDDIKESISGIHIMPMGRTDLAKTILESV
>Q2NQY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sodalis glossinidius (strain morsitans)|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEQTLWQSIDRLSELKQTFVSVTY
GANSGERERTHSIIKDIKERTGLDAAPHLTCIDATPHELQAIAQDYWHSGIRHIVALRGD
LPPGSGRPAMYGADLVALLKKVGDFDISVAAYPEVHPEAKSAQSDLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDTEIVPGILPVSNFRQLQRFAAVTNVKVPNWMTTMFD
GLDHDQETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELTYAICHTLGVRPEIKIAP
AANRAAG
>A0A6X3R8I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGSGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDDVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A396CFR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM17-1|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHAGIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFIGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYTARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A259TZP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubricoccus marinus|TrEMBL
MKVIEHYEQATEPLISYEIIPPKRGSSVSDVLEIVDALKPFDPPFIDVTSHAAEATYDEM
PDGTIKRRVKRKRPGTLGLCAAIQHRFGIDAVPHVLCRGFTREETEDALIELNYLGIHNV
LAVRGDDVSVAKRERPGRSSNVYAEDLVRQISAMNAGEYLDEGLLDAAPTNFCIGVGGYP
EKHEEAPNRTWDVLNLKRKVEAGADYIVTQMFFDTSQYIDFVERCRNVGINVPIVPGLKI
LTTKRHLRTLPRTFKVEIPEALAAEVEAADDARVPDVGIEWARQQSEELLAAGAPGIHFY
IMSNPAHVQRVVEPLRA
>A0A380X2C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Avibacterium paragallinarum|TrEMBL
MSYAKEIDTLNHYLSGVNGNINVSFEFFPPKNENMEKILWDSIHRLQVLKPKFVSVTYGA
NSGERDRTHSVVKRIKQETGLEAAPHLTGIDATPEELKRIAQDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKILAWLAKMYEGL
DDDPTTRNLVAASVAIDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A2S7IYD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella oryzae|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKSEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDIKPAAHLTCVDATREEVDRVVREFAALGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPSWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTEAAL
EVA
>A0A0B2B3L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mumia flava|TrEMBL
MDLAQRIAARGSELLFFAVTPPRVTVTRERAREIADVTQERLAPLRLDGLVLYDIDDESN
RNPAERPFPFLPTMDPAAFRAQHLTDVTTPVVVYRAVGKYDEDDLRAWLEAQDADRALTV
FVGASSRHAQPATSLVRAQELWAQTRPDLRLGGVAIPERHTRRGDEHLRLIAKQEAGCSF
FVTQVVYDANAAKNLVSDYRYECVARGLDPVPIVFTFSVCGSLKTMEFLDWLGVDVPRWI
QNDLRHADDTLQASYEHALGAARELIGFCRRMGVPFGVNVESVSIRRAEIEASVDLARVI
GGDLRR
>A0A2N2CCC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-2|TrEMBL
MLRDKIINRESGMIFYGLTPPKSNNTDEKIEAISKKHIARIKELDVDGVIVYDIQDETER
THEERPFEFIHTVDPSLYSRHYLKELNVPRVVYRCVGNYIEEAFVEWLKDGEDQFTVFVG
TAATHQEVGLKLDEAYKLRQQHNEDMLLGAVTIPERHRLLGDEDERVGFKMSKGCRFFVS
QAVYDLEASKKFLLDYKQYCLKHEMDMVPIIFTLTPCGSAKTLKFIKWLGISVPSWLEDT
LLSSEEMLSKSIQLITVIYKELTKIAKAEGIPIGCNIESVSIRKEEIEASILLAKEITAF
IKQQK
>E3BIL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio caribbeanicus ATCC BAA-2122|TrEMBL
MGYTHASHIDALNQNIAELSDNIKVSFEFFPPSNEQMQTTLWNSVHRLKVLEPTFISVTY
GANSGERDRTHSIIKDIQAETGLVAAPHLTCIDASRTELEQISDDYWSNGIRSIVALRGD
IPPHGGKPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIIPGILPVSNFRQAARFAKQNAVKIPGWMAQQFD
GLDDDPVTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPK
>A0A2E6ZK69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia sp|TrEMBL
MIVVLKTFMIKIYLVLLKNPIDMNKLKKNLEDGFFTLTAEITPPRGADFASLTAAAEILK
PAVSAINLTDGAGAKVRMSSLAAAIYLKKINIEPILQVTCRDRNRIAIQADLLGAASFGI
NNVLALAGDSIESGEDKKAKGVFDLNSKDLLKVMQKMNKDKMTLSGAQLNENTNFFPAAA
DAPCDPSNEWKPDRLIEKYSSGARFIQTQYCYDMEILNRYMQRLVDYGLTEKLYFIIGLG
PLRSAKGAIWMRDNLFGTIMPDNVIKRMDSSKNPRDEGVQICAELMQQASEIEGVSGAHL
MAPGLYEETVSAVRLAGFIK
>A0A257S928|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiphilium sp. 21-60-14|TrEMBL
MQPHRLFAPPAISFEFFPPKTEALETQLWSCIRRLEPLKPRFVSVTYGAGGSTQERTHAT
ITRLLAETSLIPAAHLTCVGASRDEVDAVARRYWAVGVRHIVALRGDPPSGAAYQPHPHG
YDFAVDLVAGLKRIGDFEISVAAYPETHPQASSPDADLDNLKRKLDAGAANAITQVFFDT
HKYLDFLNRARAAGITAPIIPGIMPVSNFAQAQRIGAMGGTSVPAWMADMFDGLDDEPDT
RQLVAASIAAEQVRTLQANGVTEFHFYTLNRADLTYAIARILGVKPHA
>A0A7X6FH65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. SG570|TrEMBL
MSSKSENGQGGIRISFEFFPPKSEEAEQQLWNTVSELSEWEPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLATGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVTALRERGDFDISVSAYPEKHPESRDTVADIDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRATGIKIPVVPGIMPIQNLTQLKRFAGACGTSIPSWLDERFDGLDE
NTDERAKVAADVAAEQIQDLMRRGIHEFHLYTMNRSPLVSAVLERLGLQRKVDARAGAAA
>A0A3A6NH19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurivibrio sp|TrEMBL
MTTECKDKPAARPQSRFRQSITNRAEFTITFELVPSRGGRNRQIDRTLTLARDLAGDGRI
QAVSITDNAGGHPALSPEVLGLEILDMGLDVISHFSCKDKNRNEMESQLFGWDRHCLHNL
LVISGDYPKQGYRGHPKPVFDLDSVHVVDMLELMNRGDYLNQPGQATSFFKGVAVSPFKK
TEAEQLMQYYKLHRKVAAGADYVITQLGFDARKFHEVLLYMRQQELRVPVLGSVFIPSMP
LADIMYRGGVPGCVIPEKLYKQMQQEAKAPDRGKAARLTRAAKLLAVLKDMGFDGAHIGG
PCLTMADFDFMLSAMEKYQSQARELIAELSFWPEEGFFLYRKDRKTGLNLGETKSCGQGY
EKLRPVYTLSRLVHHLAFDPQSPTYKICRQSCLALHDSLLARPFAAFEYLTKFLLFDCRN
CGDCTLASLAYLCPQSGCAKYMLNGPCGGSRDGWCEVYPGQRRCIYVKTYERLAAAGEAE
QYRHGFEPPRNWLLNNSSSWLNFYLGLDNRKKQA
>A0A7X8IL01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MKSGSNLEKVLKAGHFAVCTEIGPPKSCDAEVIKRHSETLNGYADAYNVTDNQTAIVRLS
SLAASSILVTQGLDPVLQMTCRDRNRIGLQSDLLGAAALGIKNVLCLTGDHQSFGNHPEA
KNVYDLDSIQLIHTVRQMRDEGRFLCGEEMKVRPAMFIGCVANPFADPFEFRAIRLEKKV
AAGADFVQTQAILDMERFERFMEKVRERGLHERTYILAGLMPIKSARMARYMQKNVAGMM
VSEEICQRLEKAEEVKAEAVELVVEQIHQVRQIKGVAGVHLMAVAWEEIIPMIVQKAGLY
PRPECDES
>A0A660JU55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria innocua|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDDVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A1Z7ZQK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium 33_180_T64|TrEMBL
MKVTEHIKKANGTTQFSFEILPPLKGQHIQSIFDNIDPLMEFKPPFIDVTYHREEYIFKD
VGGGLLKKQIVKKRPGTVGICAAIQNKYSVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKTETYFKPEKEGHHYASELVSQITDLNKGLYLDEELQNCSETNFCTGVGAY
PEKHTEAPNLDSDIHFLKKKIKNGAAYIVTQMFFDNEKYFKFVDKCRNEGITVPIIPGLK
PIATKKQLNLIPHRFHVDLPEDLIVEIVKCKDNSQVRQVGVEWCIQQSKALQKAGIPVLH
YYSMGKSDNIKAVASQVF
>A0A2D5N2Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MANSLFQNNDQTFIFTAETTPAVSTNLKENILKVESLIGVADAINITDAPNCQPKLSSLV
VAGEIQKSGLEVILQITGRDRNSIALESEILGALSLGINKVLCLSGDKPPENGPKAVNEM
NSTNLINLLKRMSNGTLINGVEIKEPMQLISGCADSIHDHFVRDQHSKFFKEKVNLGVNF
VQTQYCYDLELCQKYSHFIMDNKLSGTNFLIGLGPLKSAKQATWMRENLYGVKIPDSIIE
RLDQAANPLNEGKRICEELIEKLMQMPGISGVHLMGPNCENQCAELIKTFR
>A0A3A9ZRH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora endolithica|TrEMBL
MALGLPSVLPNPQPAIGELIRDHQPTFSFEFFPPKTAQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVALTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGAGVRNVLAVR
GDPPGDPNAEWIPHPEGVLYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDIDADTAHFVR
KCRAGAEFAITQMFFDAEEYLRLRDRVAAAGCDTPILPGVMPVTQIGTIARSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQASEMCARLLDEGVPGIHFITLNRSTATREVWQHLQ
AGARV
>A0A2P6C3N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinibacter sp. 10B|TrEMBL
MKVTEHLERASDTLISYEIIPPKRGGSAEQMLDVVEELMPFDPPFIDVTSHSAEVSYEQT
DDGTWERCIERKRPGTLGLCAAIEARFDIDTVPHLLCRGFTREETEDALIELNYLGIDNV
LGIRGDETGFKKPIDGGRSRNEYAVDLVRQIEDMNNGRYLEDLKDAEPTDFCIGVGGYPE
THFEAPNLTWDIMRLKQKVEAGADYIVTQMFFDNDYFFEFVEKCRDVGIEVPIIPGVKIL
KRKSHLRLLPKYFHTEIPEELTAEVDAAEPEDVEKIGVDWAIQQTEELMEAGVPCIHFYI
MSSAQTVKKVVEPLRETA
>A1KTL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A1Q8E3C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. Rd 27.2|TrEMBL
MSKPAFSFEFFPAKTEQGGQKLLNTYDELNKLAPSYFSVTYGAGGSTRSRTLDIVQTLCA
RGDTDIAPHMSCIGDDKVEIAGLLDHYKALGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGEHFRIEVAAYPEMHPQARSFEFDVDNLVNKYQAGANAAITQFFYNADSYLYLR
DTLEKRGIDTVAQPLIAGIMPITNSSNLVRFADSCGADIPRYVRKRLADFGDDRSAIREF
GFEVVYRLCERLMSEGAPAMHFYSMNKVEPNKRLVEALGLSA
>A0A432CUR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio aquaticus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELIQIADDYWANGIQSIVALRGD
IPPGGGAPDMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRSVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAQQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>F6IE34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. PP1Y|TrEMBL
MTTPIIHPNWARPALNMVDGYSLEITAKDVDSLRAAAPGILPETPIALTFLPGEEFDARV
AAARTVRELGFEPMPHFSARRITSRDEFERYLAAVTREAGVKRSFIIAGDPAEPEGPFAD
SMALIATGDFERNGITAIGIGGHPEGHPNMSDEQCWQVLEDKCNAIVARGMAPLIVTQFA
FDADAVLAWLKELRERGIEAPVRLGVPGPAGIKTLMRFAARCGVGASASVMAKYGISITR
LIGSAGPDKLVKSLEQGLGEEHGPVRLHFYPFGGLEKTVAWINEFARKN
>A0A0F4WNW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. IBUN13A|TrEMBL
MRIVDLLHKQGMNLNIKPSSKAECINILVDLMDKTGNLSNKEEYKKAILAREDLSTTGIG
DGIAIPHGKTNAVKKASLAAAVCKDGVDYDSLDGMPANLFFMIAVPDNSDNLHLEVLARL
STILMDEEFRKKLINCTNKDEFLKLIDEKEAEKFPEEPQKDVKSGSGSYRVLAVTACPTG
IAHTYMAAESLENKGKEMGVSIKVETNGSGGAKNVLTKEEIEKAECIIIAADKNVEMARF
NGKKVIKTKVADGIHKAGELINRATSGDAHVYNHEGGSEDTSDSGSDESIGRQIYKHLMN
GVSHMLPFVIGGGILIALAFLLDDYSIDPSNFGMNTPVAAFLKTVGGEAFGFMLPVLAGF
IAMSIADRPGLAVGFVGGVLAKIGTTYASAFDSSISPISGGFLGALFAGFAAGYLVLGLK
KVFDLLPDALEGLKPTLLYPLFGIGLIGLIMILVNPFFGSINIGITNVLNSMGGTSRVLL
GIVVAGMMAIDMGGPFNKAAYVFGTASLASGNYEVMAAVMAGGMVPPLAIALATTFFGNR
FTDNERKSGITNYIMGLSFITEGAIPFAAADPLRVIPSCVIGSATAGAISMIFNCTLRAP
HGGIFVVPVIGNPLMYLAAVGAGSVIGMILLALLKKPIKK
>A0A1X1WF90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium gordonae|TrEMBL
MTSGCPKRMEFGPCGGVRPDGQCEMRSGACAFVDFVPWSGPLVVDRPAAAAPLVLTDFSC
TPFDRDDVAATAAVLAPSCDAVLVGEHQNRPDFPPTLMGSLLLDAGVTPWITLSCRDRNR
VVLEQELRGLRTIGVDTVLCVTGDGRGYDVRPDVTQTFDLDGLRLVSLAASLGVLPAAPE
TPTAPPIAARPARLVEKQRAGAALAVLNHVPLPDMIADFMKSARAQGLSIPVIAAVAVFT
DSVSAAVLKGLPGLELDPAVTERVLGAADPIAAGISAAVEEARALLSIEGVAGVNVSGLG
SASGARVGAEIKAEVGRLIREGVSS
>X0ZGW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSFKEKLKTKKFIKTIEFDLPPKMKLEDGFDTIEEMIADDNIDAINITDSPGGHYRINSI
ALAVLLRERTDIPIISHLTCRDRNVIGLRGNILA
>A0A0F9DP33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MAKRPAFSNLMKAIQDGHFVFTGELEPKKILNLDKIIHSAKEMKKTGRIIAANITDGPQG
DAYMSSMVPSYMVQEKANLEAVWQVTVRDRNRIALFGDVIAGAVLGLKNILTLTGDHTAL
GDHKKSRPVYDIDSTQFAEMLSMMIDDGTDYEGNEIKGGKIEMNFGCVANPNSDPREPEI
LKVGRKVEQGIDFIQTQTAFDIDQAKEFLKELEQFNVPVLLGVFPLKSHGIA
>A0A7Z8VPK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium CS2|TrEMBL
MTIKNKADLFSFEFYPPKTEQGDLNLEQVHRDLAKLNPDFFSVTFGAGGSTRDKTYDTVV
KIQKNGVSAAPHLSCVASTKENIREILANYREHGVSKIVALRGDLPSGMMSAGEFRFANE
LVDFIRAETGDHFQIHVAGYPEVHPQAGNATEDFNNFKRKVDAGADAVITQYFYNAEAYF
YFLDKCEKSGINIPIVPGIMPITNYAQLFRFSDMCGADIPRWMRKTLECFGDDKASIMAF
GEDVVSKLCQELLDNGAPGLHFYTMNQSKPTLAVWDNLSFA
>N4WEM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gracilibacillus halophilus YIM-C55.5|TrEMBL
MTLLQKLQNEIVVGDGAMGTLLYSHGVDQCFESFNLTNPEQVQRIHQSYIAAGANVIQTN
TYGANFIKLSRYGLEEKVHQLNQQAVKIAKRAANEDTAVLGTIGGIRGVQKRITSKKEII
RSFQEQFYTLLSAGVDGILLETYYDMDELMTILKIAREETSLPIVTNVSMHEPGILENGT
LLADALHQLEELGSDVVGVNCRLGPHHMLEALETVPIPNHAHLAAYPNASFPAYENGKLV
YHQHAEYFKQCAASFREQGVRLIGGCCGTTPEHIAAINDATQTLAPITSKQVKPKVDIIT
QAAPPHSTATSLKDLAKERHTVIVELDAPKHLDTSLFFQGVRELDDIGVDAITLADNSLA
TPRISNTAIAMKMREIGIKTKLLIHLTCRDRNLIGLQSHLMGLHTLGFNEILAITGDPTR
IGGFPGASSVFDVTSGELTRLIKQCNQGRSFAGTSLQTQTNFHVAGALNANVQKLDRTIK
RMKRKINNGTDYFLTQPIFTHEKIISLYRETQHLDTPIFVGIMPLISHKNAEFLHHEVPG
IGLSDEVRARMQAHRNKKDAKQEGLQIAKELIDTAIHYFHGIYLVTPFMDYHLTVELTKY
IHDQTKNQSMRKEHVHYDDVY
>X1UU35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
GVSIPDNIMKRMEKAGESGQEEGIKIALEIIDSIKQKQGVSGIHLMTLGFESIVQRIITE
AGLVTEKNNPFFSKQ
>X1V5G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MVAEANRLKNAVIDPGTFCITWEQVAGKGAFEKQQETIFQNAQRAAKEGKVHGISITDSP
SGNPAISSEMLCAEIKRLGIEPLVHLALRDKNRNQVESLLYGLAAASVRNLLVVSGDYPT
KTALGGKAKPVFDLDPTHVMQLIGLMNRGLVITLSSRP
>X1PU25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
FADPFEFRVVRLAKKVKAGADFIQTQAIYDVAKFVKWMEMVTERGLDKQVHILAGVIPIR
STGMARYMRDYVSGVSVPDEIVTRMEQAENAKEEGARIVLEIIEQLKEIAGVHGIHIMAV
GWEDIVPEIVEKAGLLPRPVL
>X1TQD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
SKQGQLDRLKEIIPAKDWSTSRDGGPRRLNIREPHHKKMGTSEEKKTEEAKTPVSSVKAN
SNLRRILDGGEFAVTGELGPPKGADAEIIKKKALYFKDSVDAVNITDNQTAIVRMSSIAA
GVILSQMDIEPVIQMVCRDRNRLAIQSDILGAAALGIRNVLCLSGDHQKFGNHPQAKNVY
DLDAIGLIQVLKSMRDEKKFLSGDSLTVSPQLYIGAVENPYADPYEFRVIRLAKKIEAGC
DFIQTQGVFNVKKFRDWMKIVRD
>X0UZT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MVSKFKQVLNSGKFVITSEVAPPKGTNIEKMHHHIDLLKDKVDAINITDHQSSVMRFPSI
GGCLAIKEQGGEPILQMTCRDR
>A0A7Y3XA57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas azerica|TrEMBL
MKFDDEPVPGYSLPILPGHTSPGRFERVLRAGKFAITSEIDPPDSADPAEVLKRAAVFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYSTILQISCRDRNRIAIQGEILGAAAMGAC
NLLCLTGDGVQAGDHPQAKPVFDLDSMSLLETARTMRDESRFQSGRKLTSPPKLFLGGAA
NPFVPPRDWRPHRTAKKAAAGAQFIQTQYCFDVPLLREYMAKVNDLGLLEGPNRIFILPG
IGPLASARGAKWIRENVPGVHIPDAVIKRLEGAENQKEEGKRLCMDLLQEIREIPGVSGA
HIMAYRQEHAVAEIIEKTGVLEGRVPWYPGRDNPEDLNPESPDALSSTPETV
>N9M8M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter variabilis|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQRNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHKIAGIVITPHMLRVLAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVET
KKELVPQLAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A8B7HU83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcebus murinus|TrEMBL
MSLVTTLTSVWQPGGQVHLAEMDGVAFPPTLNAEAGLDLHLLRHGSGYPKGHPEAESFEA
DLKYLKEKVSAGADFIITQLFFETDTFLHFVKACANMGVTCPILPGIFPIQGYHSLRQLV
KLSKLEVPQKIKDIIEPIKDNDAAIRNYGIELAVNLCQELLASGLVPGLHFYTLNREMAT
TEVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRW
GNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELSSEESVFDVFVRYLSGEPNQNGHK
VTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQ
KAYLEFFTSRETAEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREI
VQPTVVDPISFMFWKDEAFALWIEQWGKLYDEESPSRMIIQYIHDNYFLVNLVDNEFPLD
NCLWQVVEDALELLNRPTQSEREAEAP
>A0A7T7WHB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter variabilis|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A6L8THB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia massiliensis|TrEMBL
SKGAVVSPCSDSVDAQLAKMERKVAAGADYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGI
IIPKSAGMAKFMNNNVAGIHVPDEMIEELKADKEKTKAGITGVEIAARIIKECKPYCQGV
HIMALGWESKIPALLEQAEI
>A0A0K1NG61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ottowia sp. oral taxon 894|TrEMBL
MKHALSLEFFPPKTPEGAEKLRATRARLYALQPGFCSVTFGAGGSTQDGTLAAVREILAE
GMPAAPHLSCIGQTRESIRRLLADYRAAGVKRIVALRGDLPSGYGLGGHFQYASDLVAFI
RAETGSHFHIEVAAYPEMHPQARSPRADMDAFAAKAAAGADSAITQYFFNADAYFRFVDE
LAARGITLPVAAGIMPITNATQLLRFSDACGAEVPRWLRLRLEGYGDDLASIRAFGLDVV
AALCQRLLQGGAPSLHLYTMNQSEAALALAQRL
>N1W5F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira terpstrae serovar Hualin str. LT 11-33 = ATCC 700639|TrEMBL
MHISQILGKKQTTISFEFFPPKNAEASEDLFRNIQELSQMNPAYVSVTFGAGGSTRDLTH
DLVVKLQEQTGLTIVSHLTCVGSTREEIREILKRYEKSGIHNIMALRGDPPKGQTEFQKT
ENGFEFAGELVGFIKKEFPQMGIGVAGFPEGHPSTPNRLKEIENLKWKVDQGADYICTQL
FFNNNDFYDFVERCEIAGIKVPIIAGIMPITSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDAYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRKIYESLGIRNFDSIG
>A0A1Y2Q698|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp. IBVHS2|TrEMBL
MSLPISLEFFPPKTPEGAEKLRGVRRQLYALQPEFCSVTYGAGGSTQEGTFGTVREILAE
GVDAASHFSCIGATRASVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQYASDLVAFI
RAETGSDFHIEVAAYPEVHPQARSPESDLQAFAAKVKAGANSAITQYFYNSDAYFRFVDD
AYRLGADVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDDAASIRAFGLDVV
TDLCDQLRNGGVPAIHFYTMNQSAATLEIVQRLQPL
>A0A1U8CAN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesocricetus auratus|TrEMBL
MSRREAKVLPAGHCYPSLGMWASEAGCVRLSVPPSIRNPAMVNEGSSSGSESSKDSSRCS
TPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFLDV
TWHPAGDPGSDKETSSMMIASTAVNYCGVETILHMTCCQQRQEEITGHLHKAKQLGLKNI
MALRGDPVGDHWETEEGGFDYATDLVKHIRSEFGDYFDICVAGYPKGHPEAESFEEDLKH
LKEKVSAGADFIITQLFFEANTFLSFVKACTEIGISCPILPGIFPIQGYTSLRQLVKLSK
LEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEVL
KQLGMWTEDPRRPLPWAVSAHPKRREEYVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSS
SPAFGELKDYYLFYLKSKSPREELLKMWGEELSSEESVFKVFEHYLSGEPNQHGYTVTCL
PWNDDPLAAETSLMKEELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYL
EFFTSREIVEALLQVLKKYELRVNFHIVDVQGKNITNAPELQPNAVTWGIFPGREIIQPT
VVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFLLDNCLW
QVVEDTFELLNGHSTRGEAQAP
>A0A4Q7CD62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGK
ARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVTSGKEFSPKIARFSC
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAKLLLKTEVLSKHSLV
GCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQT
EILKEKLIPTVPLEIRGTSSWKNWYLATEA
>A0A3D3UWB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MERNRMKQKIRDKSNFIVYAELTGGPGFKFGPIEDFLKAYKDAGASIIPNSFDFVGITLT
QNPGGVANIQPADVISRLMSKDLLGGLDVLPHVTCKDHNTEGIVSVLVGHRHAGVSSILA
MTGDKPIGTKGVFELDSIGLLNLIRNMNNESYIKARPDGLENVHQFFPGAAVSPFKYTVA
SQMQQYYKMEKKIASGAEFFITQVGWDWKKSLELFRYMDENNLDVPVIGNVYCLSTLTPA
PRLMHDIKLPGCFVSDEFLAKIYSEKVDDHLERAAQQVAMYKSLGAAGVDIGGVHDFDMF
VRILERAAEIGSGWEQFKDNLCWPAKNAFYLYDETGSRTQLPKPGKKFGQRFFNFCHWAF
LDPDHLGFHAFKKTMAFLGTEKGKGAVYKLFNASEKSFKYLLFDCAECGDCFLPENFGLC
TIGGCEKGMDNAPCGDSTVDGYCGNNLERVCIGELIYDAAVAEKDGEERLRNIINQPRNP
ALEHTSSILNYLFAKDHTMKAPVITIGESIHASIPKTGKIMSQLAQLGPDAYSKPSGPLD
YIRALIDSQARDGADYIAVNLDAFGEGNPQVSVDMMIEYVRLVRKWGHGVPICIDSSDND
VLIAGLKQWYDTEKAVKQPLINSVKVYTMDQILPLKKDFDFAFIGLLVSEDAPAGAGGSH
SVEELYSLAKQLFDKAVGEYGFKPGEIFFDSTVFPLAIDMPMEPDVPGYTYRAFETIRKI
KSDPGMKGVHCSLGVSNSVRDLPGRRIGICRAYLAKAMEYGLDTGIVNVAHRYGRVEPAP
ELLELVDAYAKMDGSAERMNKSMELMGKFCRENRK
>A0A388QCL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MTSINLQEKLKRGTLLADGALGSELYARGIIHGSCLDALNLTDPAAVLGVHAGYLQAGAD
LIETNTFGANPFRLASHGHAEQVAAINQAGVVLARQAAAASGRAVAVAGSVGPLGVRLAP
FGRVKPEAAYAAFSAQIGALLAAGVDALVLETFSDLMELSEAVRAARDCAAAHPPVLLVA
SMTFTRDDRTQLGDSPAHVARTLAGLGVDVLGANCSIGPAQLLRVLKGMHAAAPQLPLSI
MPNAGMPELSGGRVVYPAGPDYFAQLTPDWLATGARIVGGCCGTTPAHIAALRQALDTPR
TASVRSVPARPSSPAESLPATDEPTKLATQLQSKRFVITVEMSPPKGYTPHKVLAGAHML
AEAGADVINVADSPLARMRMSPWAVCHLIQQQVGVETVLHFPTRGRNLLRVQGDLLAAHA
LGVRNVFVVMGDPANIGDFPQAFDTFDVAPTALLQLVKQRFNAGMDQAGQDIGQPTSFVA
ACALSLSAPDPAREIKLLRKKLECGADFALTQPVFDAQVARDFFARYAAEHGPLQLPVLV
GVLPLYSERHAGFLHNEVPGVHIPEAIQRRIAGAADAPAEGIRIALELLAELREITPIRG
AYLQPPFRRYELAAEIIEHLRAQD
>A0A0R0RWT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MSHVSPCFQQNQFFMLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPESIDKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFCIGVAFNPFKYVEAERDSQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
SGKEFSPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
FLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A7C2ZW83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MADGADWRPGGNMTSNDTFLKRLQQGVLIGDGAMGTMLYQRGVFLNSCFDELNLSQPGMV
LEIHKAYVNVGVDFIETNTFGANAFKLGRYGLAENLEQINTAAVRIAREAAGQDVLVAGS
VGPLGVELTDFGPVTADQAVDAFARQLQSLTAAGVDFLLLETFSSTDELLAAVKAASQCT
DLPVVAQMSVNEDNETIYGEPVAAAMGRLAAEPTVTVVGLNCSLGPSEMLSTLELIRSVT
HKPISVQPNAGMPRHVEGRTLYMCTPEYMAEYAKRFFEKGARIIGGCCGTTPEHIGQIIK
AVRPLHGATVSSVRVLSMATVASAQAAQAVEPVPLPQKSRIGAKLAAGEKITSIEITPPR
GLDIGPVIEKARLCAEHGIDAINIPDGPRASSRMSPMITAVRIQQSADIEAILHVCCRDR
NLIGMQSDMLGAAVIGLNNVLIITGDPPKMGEYPHATGVFDLDSVA
>A0A372YM66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium AM07-35-1|TrEMBL
MHPLFMKQKRLLFDGAFGTYYASLYGNEEPCEMANVKAPSRVAAIHEEYLKAGANAIKTN
TFAMNEAVLDCSKAKREELLRQGYRIAKRVATPYQASVFADIGPCVETRTRSAFTQYKEL
VDVFLEEGADCFLFETLPNDHGIHEIAAYLKERCPHVCVLVSFAVTADGYTQQGVPLTKL
VKAAHEDENIHGFGLNCICGPMHMRRLLKYFDTKKDTILIMPNAGYPTILANHTYFRDNS
SYYAQEMEKISSMGVRILGGCCGSKPPYIQKIKERLQEEAVLSLPTPAANDPVLYKDCNP
LRKKLQRKEKVICVEFDPPMDCRIERFMNDAEYLKEQGIDAITIADCPIARARVDSSLLA
CKLHRELGIDVIPHMTCRDRNINATKALLFGLNIEDIYNVLVVTGDPIPAADRQEVKGVF
SFNSQLLAGYIRDLNETTFPHPFLIFGALNVNAANFKQELLKAKQKIQQGVQAFLTQPIH
SAKGLQNLQQAHRELDAWILGGVMPIVSYRNALYMKNEIAGIEVDDAILSRYEHKNREEA
AVLAVTIAKATIDEMASFVDGFYLITPFHRVEIMQQIIAHIQQMDD
>A0A172TAS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus puniceus|TrEMBL
MSQSFATGASPQTRVSIELVPRSRSGLRAELEMVREHLPGIDTINIPDFPRFSTRSWMGC
AMARPHHRAIPHIRAVDINPREPLPMLDTLTAHGITEVLIITGDAPADMSAKVYDVDAVD
VIRRFRRELPDVRVYAGLDPYRQSFARERDYLERKLDAGAVGFFTQPFFDLRLMDAYADL
MPEGADVWWGATTVTTEQTLNYWRARNHAVFPRSFEPTLEWNRTFAAAALDFARERAQHV
YFMPVKADAREYLEGIV
>A0A1Q5MKP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB00455|TrEMBL
MRELLAQGRRSFSFEFFPPKTDAGERTLWAAIRRIEPFAPSFVSVTYGAGGSSRDRTVEV
TKRIAAQTTLRPVAHLTAVGHSVAELRHIIGQYADAGIRDVLALRGDPPGDPKGEWTPHP
DGLTHAHELVTLIRQLGDFTVGVAAFPERHPRSPGWTEDIRHFAAKCRAGADYAITQMFF
HADDYLRLRDRLCAVGCLTPVIPEIMPATDFRQIRRFAELSDARFPDALARRLEAAKDDP
EAGHRIGVEYATAMAERLLAEGAPGLHYITLNKSTATLEIHQNLNVSPDPATTITE
>A0A1P8NDH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium sp. P6-10-X1|TrEMBL
MTADADQVDSAEESEAQFEVLPLRGISDRVGAHLPPGTRVTVTASPAHGLEATLAVACEL
AGRGFTAVPHLPARQIRDPQEVRTILARLDAAGMDEVFVIAGDAPRAAGDFDGSLSLVEL
LAAEAPRLAIGVGAHPEGHPFVDEQEAMRLLRAKAEHASHLVTQMCFEAAPLLAWVRGLR
EAGITVPVRPGVAAAVGTARLLRIGARIGVGRSLRMLGGEGSGVRRLVGPGSWDPGPLLD
ELDQAREEPGLALAGPHVYTFNDLEAAARWRADA
>A0A5D0NJG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura chibensis|TrEMBL
MPRLRPERPPTVRELLASGGRSFSFEFFPPKTDKGARNLWRAIRELESLHPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVRHPEGVEYAADLVRMIRSYGDFCVGVAAFPYKHPRSADIDSDTRYFVEKCRA
GADYAITQMFFRADDYFRLRDRVAAAGCDVPILPGIMPVTQLSTIERSEQLSGAPFPPEV
RARFEAVAGDPEAVRRLGIEHAAELCRELLDQDAPGIHFITFNKSTATREVYSLVDGAGY
GARGSVPPMTA
>A0A2H1GHR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymoseptoria tritici ST99CH_1E4|TrEMBL
MHITKKLAAAHEKGDATYSFEYFPPKTAQGVQNLYDRMDMMHGFGPAFIDITWGAGGRHS
SLTCEMVKVAQSAYGLETCMHLTCTDMELSKVDDALKEAYNAGCTNILALRGDPPREQEK
WVETQGGFRYARDLIKYIKKKYGDHFDIGIAGYPEGPDETTTADEHIVYLKEKVDAGGTF
VVAQMCYDAELFIEWVQKCRDAGIPESVPIIPGIMPISTHAAFIRRANWTQARIPPAWHE
ALEPIKNDDSAVREVGRDLIVEFCQKLMAAGIMHLHFYTMNLAAAVRMVLEKLDLTPSAE
SPHPDIKPLPWRQSLGLNRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
SLDEYGIGLKGTNEHNRKLWGEPQTIDDISKLFVKYMSGKVETLPWSEAPINDEANVLVK
DLIELNNRGLLTINSQPAVDGVKSSHPTYGWGPRNGYVYQKQYLEVLVAPELIDTVIQRM
ENDEDITYYAVNHSGELKTNVTADGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYY
LGLEWSKCYEEGSKSRALITELTKSWYLVNIVHNDFRNQGGIFPIFDGLQVPGVNVEKLA
NGITNGHAENGKTTEENGKPETNGVPDGNNVVNGADKKA
>A0A1B8AD24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium poae|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDAEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHILERLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAVYPEWEATGLEAGGRAEAVNTRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVRLWDHPKTRQDINDLFVKHIQGELSAIPWSE
EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PSNEWEILKTKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGSTETSPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNLIHHDY
VNKDALWEVLSS
>A0A846JKC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNEKKLVFSFEIFPSKVTSSITTIYETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKDIIGE
YNYAFELIEKIKASNNFGISGACYPEGHIECKSLDQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQEKSINVPIQAGIMPVVNKKQIERIVKISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDIAV
>A0A8F8DLJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. TC-EC600-tetX4|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A496NXA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MENIREYLKNNVLLFDGAMGTYYDELTDDGIGCELANIKNPELIKGIHNEYIEAGAKAIL
TNTFSTGIDAFSGDRELQRKVIVAGIDIALEVAKSRAYVFADMASINADSNSAAFEEYKI
IADIFLEKGINNFYFETRNSTIGLKSIGEYIKEKSPEAFIIASFAVMPDGYSSEGYYYKT
MFKEISESGFFDGVGLNCVSGANHMAKLLKDVDTEGLYLAAMPNAGYPIVRDNKIYYGSL
ANYFAAQIEDILDMGVNVVGGCCGTTPKHIELLKKSMSGMLIKPRKSVKKEKNISQKIRL
NRFEQKLISGQKPIAVELDSPIDTNIAKFIDNAAKLKSAGADIVTIADNPIARARMDSCL
LACKVRNELDFDVLPHMTCRDRNVNAAKGLLLGASAMGVDNVLVITGDPIPNAQRDEIRS
VFEFNSVKFANFIKSLNDEVFESPMNICGALNVNAKNFSAELRKAKRKQENGVKVLFTQP
VLTQRAIDNLKEARENLDVKIMGGIIPIVSERNARYMQSEVNGIYITDDIVEKYIGKERE
EAEEIALSMSKEIANEIYDLVDGYYLITVLNRVNLMERLIKTVKEVCENR
>A0A378W672|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium senegalense|TrEMBL
MSDFSEALRERPLVGDGAMGTMLHAAGNSLDRALPELNLSKPDAVSTVHDSYIDAGVDLI
LTNTFGAGRLRLAEHGYAGDVAAINHAGVQLARRAAAAVDRRIFVGGSVAPAVSASQRSW
VSAEQRSAAMREQIVALSESDVDLLVFETFGYLDELIEAIRIATELTDLPVLAQATFTAD
GRTPGGETTHEVATALAGLPVAVIGANCTVGPQRMLGVVEELRQATSLPISAQPNAGLPR
RIGGRRFEYNIDHEYLVRYALRCVDAGASIIGGCCGTTPAQLRKVVAAVSERPGRPAPTV
RPRPAVPDLFAQQLSRGFVVAAEIAPPIGGTTQEATELAGQLRSAGADLVLVAAPRDPRA
HLAPTSLALHLQQEIGLETITTVTTWDKTIMSLQADLLGAHAFGTRTVVCETGNPPLRGE
YPNADGIWEVDSVGLIGLMAELNTGRDCNGLSMATKTSFKIGARCNPGAEDLEAEIARTR
AKIAAGAQFLITRPVYELEGLRRMRRELADDGIPVFLTVAPLGGYAEAEYLAYEVPDVTI
PPKTLSDLEAAGPHDRETAAGLAGDLLNEAKSLADGVVVVIGGDHEIWRGLLTTAGRQRP
>A0A7K6NDI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedionomus torquatus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVS
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEKDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A3D2KAW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MNQAAELRERIQHEVLLMDGAMGTYYSRLHPEMGEAEYANEEHPEWITEIHKQYLQAGAQ
ILRTNTFAVNHMLFEKEQIPVVLSGAVECARSAVEQYRKEEDTDRPIWIAASIGPIRYSD
EQEERDVMQEYRMIGECLLGLGIRIFVLETFDDWKMAKRISEMLREWAEVQGEDIYILAQ
FSVNRGGYTKAGYSMQRLVSQLEQLKSLDGFGFNCGIGAAHMNQLLSKIHFQKECTLSVL
PNAGYDHMLRGRQVYVDHPDYYSAMMRQILQNGANIVGGCCGTTPEYIRMLAGVLQEHER
PQNKQIQAVRKEITDDTERNPFIEKLEQGRRVYVVEIDSPFNGKAEKFLEAGYRLKENDV
DLVTISDSPMARPRAEAFEMGVYLASKTGVRVMPHVSCRDRNVIALRSSILGGHINGIRD
MLIITGDPVARDDRGTISAVFDFNSIKLMEYVSNMNEEVFTGEPFYYGGALNYAGVNMEA
IAGRMRKKMEAGCQYFLTQPVYSEEDISRVRELKKMTGAKIILGIMPLVSYKNALFMKNE
MPGIQVPEKILSRYDPDMSRLDAEAVAEKVSVEIGKKAMDFADGFYLMTPFNRVHLVNRI
IDRLRALDKK
>A0A369T983|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferruginivarius sediminum|TrEMBL
MPAGRKQQIVDFVSDYSIETTPGSAAKTPDYREHLHEGTKVAVTFLPGSDYRDTVATAKR
LREEGMEPAPHIAARSLKDKAQLEDYLTRLRNEAGITKVVVLAGAVDSPVGEFSDSMQLL
DTGLFDAHGIKTIGVAGHPEGSPDIPEQAVWQALRWKQEFAKRTDAEMYICTQFVFEAQP
VIDWDKAVRREGVDLPVHIGVPGLATLKTLINHARACGVGPSMRFLTRQAKNVTKLMTVN
APDLLVSDLAKYAAEDPDCGIKRVHMYPLGGMRRSAAWANAVAEGDFQMKADGRSFEVNR
DIG
>A0A5K8AAH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina ovata subsp. ovata|TrEMBL
MHVGNLYATQQKPAISFEFFPPRDEKAAEKFGAVVDTLAELSPDYMSITFGAGGSTRDGS
YQAVNQLLVEKKIPTVAYIAGFGLAPDEMTHELDRYRDLGVETIFVIRGDKPQDPDFKPH
PESFSYASEMIAFIKSRYDFCLGCAGYPEGHIQAQSLEADIGFLKQKQDNGAEYVVTQYC
YDNDTFFRYVEKCRSAGVSIPIIPGIMPVYTLKLTQMLSKICGTTITDEMQRGLDQLDAT
DKDAVLDFGVDFAVEQCRGLLKKGVTGLHFYTMDRSRSTRAILTRLREENLV
>K1KUQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solibacillus isronensis B3W22|TrEMBL
MGLLEELQTRVLTADGAIGTLLYSYGLDYCHEEMNIARPDIIEKIHSEYIAAGADIIQTN
TYGANRIKLARYGYENRVKEFNEAALKIAKRAASLDGQYVLATIGGIRGIRKSDATLDEI
LAAFQEQAEVLLAGEPDGFLLETYYDFEELSHCVHLLRSMTDLPIIAQVTMQEPGVLQNL
MTLNEAFQDLERLGADIVGSNCRLGPFHTIQAFEGVNLPNKAFLSAYPNASLLDIEDGRV
VYESETDYFARAAVELVNQGVRLIGGCCGTTPKHIAAVKKRLANMQPIETKEEKHRSTQF
VRIPEPRKQEPLHEKAKRERSVIVELDTPRHLEIDGFVEGAKQLSKAGADVIMMADNSLA
SPRISNIAMAAILKEQGIRSLPHLTCRDRNLIGLQSHLMGLDALELHDILVVTGDPTKVG
DFPGATSVYDVSSMELISLIKQLNKGGSFTGKSLRKQANFSVAAAFNPNVRVLDRAVARL
EKKIEHGADYFISQPVYTKEKIIEIYEATKHLETPIYIGIMPLTSSRSAEFLHHEVPGIK
LSDEVLARMAACGDDKEASTAEGIAIAKELLDTACEYFNGIYLITPFLRYDMTLELMDYV
KQYDVESKGVQSNV
>A0A4Y9LT44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium niftali|TrEMBL
MSGAMTDLTKPATADGQDGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVT
YGAGGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRG
DPPGGIGTPYSSHPDGYQSSADLVAGIKKRHSDIEVSVSAYPEKHPEARDFDADIDTLKA
KVDAGATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRAGTSV
PDWLAEKFEGLDEDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISHLLG
IRAKSAQKAA
>A0A427L3D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. 357|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRNAVNVSFEFFPPKTDAAEANLWAAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIEGYKAIGVDH
IVALRGDPPGAAGIGGAYTPRTDGYANATELTAALSRIGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLKRMT
AACGAALPDWLAGHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAVA
>A0A2T3E884|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. JAB6|TrEMBL
MSSRLESRDAGIRISFEFFPPKSEEAEEQLWNTVAELSDWEPEFVSVTYGAGGSTKAPTL
SAVCKMIHETPFTTASHLTCVGATREDTHRVIDEFLAAGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVGALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKAENGADRALTQF
FFDNDAFERYHDRVRAAGIRIPVVPGIMPIQNLTQLKRFAGACGASIPSWLDERFDGLDD
NIEERAKVAADVAAEQIEDLVRRGIHEFHLYTMNRSALVSAVLERLGLQRKVDSRAGAAA
>A0A351TQU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKITELFERGEFVVSAEVGPPKGFHIENILEEAKTYLSGITAVNVTDNQSSVMRLGSLAV
CKALKDEGLNPIFQLTCRDRNRIALQSDLLSAAMFGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVTKLESGEDLGGNPLVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGVHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKVPALLEQAGI
>A0A3D1Y6H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKITSIFEKEEITVSFEVFPPKTTTNYEAVEKAALGVAALKPSYMSVTYGAGGSTRGYTI
KIAEKIQKEQQVTTIAHLTCVGATKADIHAALGQMKEAGIENILALRGDRPKDFEGDPYV
DYHHASELVETIREYGDFCVGGACYPEGHPDAATKKEDILNLKKKVDAGCEFLTTQMFFD
NNIFYNFLYKAREAEILVPVIPGIMPITRANQVANAVRLSGCNVPERFRSIVDCFGDNPA
AMQQAGIAYATDQIIDLIANGVNHIHVYSMNKPEVAKGICDNLSAIIH
>W2XB82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora parasitica CJ01A1|TrEMBL
MKVIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMAEADIKKALDEAKDAGIQNILALRGDPVRGASS
FDECDRGFSHAVDLVRYIREKYGNHFCIGVAGYPEGHVEIKDKKADIQYLKEKVDAGADF
VITQLFYDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTSFCNTFVPDEVREAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRASESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSNTSTPRERRAMWGEAPAAKEDVRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGALSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
PSIQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEPGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSPATSP
>A0A2N0ULB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus bromii|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGVESVAHLTCINSTKADVDRNLALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYIASQGDFDIAGACYPEVHSDATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVELIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A1G6WGV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycomyces harbinensis|TrEMBL
MPVKAAKIGDLLRSGTPKFSFELFPPRDEKADGILWRTIRNLEQLGPDFVSVTYGAGGLT
REKTVETTELINAETTMLTMAHCTAVDHTVGELRNLIGHFANVGVRNILALRGDPPGDPR
AEWIEHPGGMRYAYELVELIKSSGDFSVGVAAFPEGHPRDADWETGVRHFVAKCRAGADF
AITQIFYRVEDYLRLRDAVVAAGCDIPIVPGIMPVTNIKQIERFAVLTGMAFPAALAERL
RAVEGDRDAIRDIGVEVATDMGERLLAEGAPGLHFTTLNHSRSTRRVWQNLRKS
>A0A095TSN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tatumella morbirosei|TrEMBL
MSFFHANQYEALNQSLSELNGRIHVSFEFFPPRTQEMEDILWRSIDRLSILKPQFVSVTY
GANSGERGRTHNIIKGIKERTGLEAAPHLTCIDADRDELRHIARDYWHSGIRHIVALRGD
LPDSSGKPSMHAADLVALLKDVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGADRA
ITQFFFDVESYLRFRDRCAAAGIEVEIVPGILPVSNFRQLQRFSALTNVRVPHWMSSQFA
GLDDDAETRKLVGANIAMDMVKILSREGVTDFHFYTLNRAEMSYAICHTLGVRPHSVAA
>A0A249DDB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus rhamnosus|TrEMBL
MKISQCFKDHQVISFEVFPPRKNATNIAMRPILNTLDAVKAADPDFVSVTFGASGNKPHM
GTLEVAKLIKNEFNLETVAHLPAAQLTRAQVDAELRGFQEAGIDNILALRGDIPKSGRVS
EDFPYACNLIEHIHQVGDFDVVGACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYQFRERAALAGINVPIEAGIMPVINEHQIERMATMAGVHLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A3B9CIT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIREILAQDTATISFEVFPPKKSTDFGNVEAAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGEIQKQHNVPTVAHLTCVCADRGSIGTALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKENGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIVPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNISEILKA
>A0A417TIR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. OM05-10BH|TrEMBL
MKIREKLQSGKVHISFEVFPPKTDDKYESVLKAVDEIATVRPSFISVTYGAGGGTSKNTV
GIASHIQNDLKVPSLAHLTCVSSTKAEVREVIRKLKEEGIENVLALRGDIPEGMEYPAED
KFQHAIGLIELLKESGDFCLGGACYPEGHVESETQKEDIRHLKEKVDCGLDFLTTQMFFD
NHILYNFLYKIREAGITVPVLPGIMPVTNKSQIKRICSLSGTYLPERFKALVDRFGDNPK
AMRQAGVAYATDQVIDLIANGINNIHIYSMNKPEVARAIMENLSEIVDE
>G9ZXP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacteraceae bacterium AT-5844|TrEMBL
MARIMNHFAEASPGAPAAHRTAPAAGTLQRWLTGPRVASLPQGSAMPVPALSFEFFPPRT
EALEQQLWACVRRLEPLAPRFVSVTYGAGGSTQERTHATVARLARETALTPAAHLTCVGA
SAGEVDDVARRYWDAGVRHIVALRGDAPGGEAGYVPHPDGYAYAADLVAGLKRIGDFEIS
VAAYPETHPAAHSPEADLDNLKRKIDAGATRAITQYFFDTDVYLRFLDKALAAGITVPIV
PGILPVSNFNQVRKFSAMCGTNVPDWMGHLFEGLDDDPDTRRMVAAAMAAEQVRLLQANG
VDEFHIYTLNRADLSYAIAHILGVRPLKEG
>A0A6G2EIN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. JL972|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLAGYHPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVRVPTAPHLSCVGDSKAELRELLDIYRKAGIRRIVALRGDLPSGMGLASGELRHANEL
VEFIRSETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKAQAGADSAITQYFFNADCYFY
FVERVRKLGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIDSIQAFG
EQVISEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLPRQA
>A0A8J4EBK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Virgisporangium ochraceum|TrEMBL
MALGLPSVLPRRHPSIAQLVRAAEPTFSFEFFPPKSPEGETQLWQAIRDLETLRPSFVSI
TYGAGGSTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRHIVGRLAAAGVHDILAVR
GDPPGNPQGEWVRHPEGVLYAADLVRLIKELGDFTVGVAAFPYKHPRSPDVESDTAEFIA
KCRSGADFAITQMFFDADDYLRLRDRVAAAGCDTPIVPGVMPVTSLRTIERSSQLSGAPF
PRHLAAEFDRVADDPAAVRALGLAQMSAMCDRLLAEGVPGIHFITLNRSTATREVWQQLS
LSAIS
>A0A7X2MVI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Inconstantimicrobium porci|TrEMBL
MKIKNLFEDKKVVLSFEIFPPKPTSKIDTVYNTIEELAVLKPDFISVTYGSGGSMTSNRT
VELSSLIKEKYDIETIAHLTCISSTQDDIKKTIDELKAKNIENILALRGDVPIDKVSGGS
FNYATDLIKYVKDISDLGISSACYPEGHIENKNLDESIKIIKMKEDMGAEHFISQMFFSN
DAYYDFMNRIYRNNIKSPIEAGIMPVTNRKQIERMVQLSGASFPYKFLKIIDKYENSPEA
LEQAGISYATEQIIDLVSSGIRGIHLYTMNKPHVAKKIVESIKPILDALNRSEN
>A0A1I5G6V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. NFACC24-1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGEHFHVEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>N8XPN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 56.2|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKTVHQELQQLNPEFFSITYGAGGSTRERTLAAISDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERITKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A2M7ZNP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriales bacterium CG_4_9_14_3_um_filter_30_11|TrEMBL
MKVIDHIKKAKKPFISFELIPPKRGGDLKGLLSVLEDIVKYNPPFIDITSHSAEVVYDET
KSGIQKKVKRKRPGTLGICALIQHKYDIDAVPHILTNGFTREETEDFLIELSYLGIDNIL
AIRGDDHGYIKPIPKGKSANVYASDLVKQIDDMNKGKYLEENLLDANPSSFCIGVGGYPE
KHFEAPNLLTDIKFAKQKINNGAEYIVTQMFYDNESYFKYVDLCRSQGIKVPIIPGLKII
TAKSNLSSIPKNFYINLPEELSEKIMDADKDKVVEVGVEWAAKQVKDLLKKGVPSIHFYI
MQDSRPISMLMEKLNIF
>A0A356SP54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAARKPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRDETGDHFDIAVAAYPESHPQAPSLDKDVENFARKMNAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GTDVVTRLCERLLDGGAPGLHFYTLNQAAPVLKVVDNLS
>A0A1B7L614|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mangrovibacter phragmitis|TrEMBL
MSFFHANQRDALNQSLAEVQGHINVSFEFFPPRTSEMEQTLWNSIDRLSSLRPKFVSVTY
GANSGERDRTHSIIKDIKERTGLVAAPHLTCIDATRDELKSIAQDYWDNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVENYLRFRDRCAAAGIDVEIVPGILPVSNYKQLQKFATMTNVRVPQWMATMFD
GLDDDPETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAG
>A0A0L8M6T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces decoyicus|TrEMBL
MNTLRDTLATGARSLSFEFFPPKSAAGERALWQAIRRIEPLSPTFVSVTYGAGGSSRDRT
IDVTKRLVGETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGAPNGPWR
PHPHGLRHAQELVRLVKESGEFSVGVAAFPERHPASPDWDSDIRHFVAKCRAGADYALTQ
MFFRVEDYLRLRDRVAAAGCETPIIPEIMPATDVRQIRRFAELSHAAFPEDLAHRLEAAR
DDPGAAHRIGVDHATMMAERLLAEGAPGLHYITLNRSTATLEIHQNLGLSAAVARHRPDR
HQ
>A0A2G9XJF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium CG23_combo_of_CG06-09_8_20_14_all_48_27|TrEMBL
MTNTGSNIERILDTGGFVVTSECGPPRGADAGVVRKKGELLRGVVDAVNVTDNQTSVVRM
SSLSACVILKEMGFDPILQMVCRDRNRIALQSDLLGAAALGINNVLCLSGDHQKFGDHPQ
AKNVFDIDSIQLIQAVRRMRDEGKFIGGEEIKGKPVLFIGAAANPFADPFEIRAPRLGKK
VKAGCEFIQTQCIYNLERFERWMAMVRDRGLHEKCAILAGVTPFKSVGMAKYMKNQVPGM
DVPDEMIERMKGVPKEKQTEEGIKICVETIQRLREIPGVRGIHIMAIEWEDRVSEIAKAA
GLLPRPQLP
>A0A2E9QIQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKCKNNEQVRQVGVEWAIQQTKELIEFGAPCIHFYTMGKSDNVQEIVGNFS
>A0A3D4KRJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp|TrEMBL
MSSQQHPLGISFEFFPPNTDAGRDKLMLVRDELATRNPRFFSVTYGAGGSTQARTRDTVR
TVGQTGITTAPHLSCIGSEKAQLRDLLSQYREEGINSLVALRGDMPSGMGSIGELRYANE
LVEFIRNETGDHFNIAVAAYPESHPQAANLDKDIENFARKMKAGADMAITQYFFTADAYF
NFVDKVRALGVEQPIIPGIMPITNYTKLARFSDSCGAEIPRWMRKQLESYGDDSEAIAKF
GTEAVSRLCQRLLDGGAPGLHFYTLNQAAPVLKVVDNLVG
>A0A2A5B847|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTEHLAKAKKSLFSLEILPPLKGKGIQAIYDGIDPLIEFGPAFINVTYHREEFVYKKR
EKGYLEKISIKKRPGTVGICAAIVNKYKLDAIPHIICGGFTKEETENALIDLNFLGIDNV
LLLRGDPIKTEPAFVPEEDGHHFAVDLVKQVAGLNNGEYMDEDLQNTTPTNFSIGVAGYP
EKHFEAPNLKNDLKFLKQKIDAGAEYIVTQLFYDNEKFKAFVELCRNEGITVPIIPGIKP
ISTKKQLLSLPKFFHIDLPDELVDAIENCKSDDAVRQVGIDWAIQQSKDLIDFGVPCIHY
YTMGKSLAVREVVKAVF
>A0A2G2BK78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAARNPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRDETGDHFDIAVAAYPESHPQAPSLDKDVENFARKMNAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GTDVVTRLCERLLDGGAPGLHFYTLNQATPVLKVVDNLS
>A0A6H9XYQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium SCN2|TrEMBL
MTTPDFSIEFFPPKTPEGMDKLRAARAQLAQTIKPEFFSVTFGAGGSTRDRTLETVLEIQ
HEGHEAAPHLSCVGSTRAEISAILDTYRQRGIRRIVALRGDLPSGMAEPGELRYASELVA
FIRQETGDAFHLEVAAYPEIHPQARSAQDDLQHFAHKVKAGANSAITQYFFNADAYFRFV
DEARALGVDVPIVPGIMPIGNFSQLARFSDACGADIPRWIRKRMEGYGDDAASIRAFGLD
VVTAMCERLLAGGAPGLHFYTLNQAGLTLEIWKRLKA
>A0A2T5QT77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDTAPLEASKSYPDSIEKVLHFSGK
ARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKNNYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDRVYLRCALQILICKH
LGYAGIHLSACHKPEEQMLLESYVEQYRHLEFKALEELWNSLWQVTSGKEFSPEISRFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAKLLLKTEVLSKHSLV
GCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKALEQT
EILKEKLIPTVAIETRGTSSWKNWYLATEA
>R5W295|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:167|TrEMBL
MIKDLFHKNRPIYSLEVFPPKKDADVSVIYDALDQFKTLHPSFISVTYGAGGNTAENTFA
IASYIQNQCGIEALTHLTCAAIPDELFLANFLTNLYRNGIHNLLALRGDQPRTMTDEQFA
ARYYDHASDLTKAVKSMYDFSVAGACYPEVHQEAENLQQDVSNLKIKVEQGVDFLITQLF
YDNECFYRFLEEVRRQNIEVPVLPGLMPITSAGQVKNIVGMSGTKIPKKLQESIDKYKDS
PEDLKKAGIEFTKEQMEGLLQHGVDGIHLYSMNKVEIARAIYE
>A0A7H2PW20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMATKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKAFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGYTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYVEQYRHLELEALEELWNSFWQVT
TGKEFSPEIRHFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGIGRFIFKASFWDNTLVAK
VLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSAKARLAKAVEQTEILKEKLIPTVPLETRGTSSWKNWYLGAEA
>A0A7R9JDU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Timema californicum|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSDMEETLWTSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMSAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAAAA
>A0A091B9I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenimonas composti TR7-09 = DSM 18010|TrEMBL
MPHLSFEFFPPKTDDQIAQLDRTARRLKAHSPDFVSVTFGAGGSTLSYTADTVRRLRTDV
GLDAVPHLSCVGGTRDEIRALLADYRALGCNRLVALRGDLPSGMARPGDLHYASDLVRFI
RAEHGDHFRIAVAGYPEVHPQADDALADLRHFRAKVEAGADRAITQYFFNADAYFRFVDD
CRAAGITIPIVPGVMPISNFTQLRRFSDACGAEIPRWIDKRMAAYGDDVDAIREFGADLV
AAMCRRLIEGGVEELHFFTLNLAKPTEAVLARLR
>A0A2T5QVM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLASIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLESAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A1T4YG92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agreia bicolorata|TrEMBL
MESLLTPSAAHAGCPKNMEYGPCGGVGFDGSCEVGDFRCVFLDDPLVTWHGVVPPEPDVV
PRSSGAAEMMALMKTRPIVVADFPARAMDAESLAECAALLAGPVDATLAGDHGTARVQFS
PSYRASLIRAAGLQVWTGINCRDRNRVAIEGELAGLAHVGVAGVHCVTGDHTLLGSRPDA
APVFDLDSSQVAALARAAGHLVSVGESPTTPPVELRAARLLEKTRAGADVCFVNHCGGVD
AVGRFVRESHDLGVTARFIPCVPMVTDHASARLLESFPSLVLPEGYLDRILSAADPREEG
IRAAVELSLELLEIDGVAGVNLSGGAGHGREAEFAIVLAETAQHLAL
>A0A1G9DV31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilus rhizosphaerae|TrEMBL
MNNKASYSFEFFPPKTAEGMANLRQVRAELVQFSPEFFSVTFGAGGSTRDRTMDTVLEIQ
AEGYGAAPHISCISSSKEEIRELLQAYQSKGIRRLVTLRGDIPSGEVTTGDFKYANELVS
FIRKETGDWFHLEVAAYPEFHPEAGSAQKDLENFKRKMDAGADSAITQYFYNVDAYFRFV
DAAQKLGVTAPIIPGIMPIYNYTQLARFSNVCGAEIPRWLRMRLEAYGDDLASLRAFGVD
VVTDICAKLVQAGVDKMHFYTLNQAGMIGQIIRQL
>A0A6N9U7Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces halstedii|TrEMBL
MHPLDTASAAVGTSLLEDFSLEMTGKDVPELEAADGTLPRGTRVNVTFLGNEDTRMRLDA
ARAVKRLGLLPVPHVSARRLTSRTDFAQFLAGLRDDGTATHVFTVAGDPVLPQGPYDSAL
ALIESGLLQEHGVRHVGIAGYPEGHPALTDDTLRSALRDKVASLTAHGLTGHVTTQFGFD
PDPVLSWLEHVRDQGITLPVRIGVPGPAGVRRLLSYATRFGVGTSASIAKKYGLSLTNLM
GTTGPNAFLRTLAERYDPTRHGEVKIHFYTFGGLRATAEWIARFREDNPV
>A0A7K1GGH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella ouciana|TrEMBL
MKVTEHIKKANGKTQFSFEILPPLKGQHIQSIFDNIDPLMEFKPPFIDVTYHREEYVFKE
VENGLLKKQVVKKRPGTVGICAAIQNKYGVDAIPHILCGGFTKEDTENLLIDLDFLDIEN
VMALRGDAVKSETYFKPEKEGHNYANELVAQIEDLNKGVYLDEELLNSSKTDFCIGVAAY
PEKHMEAPSLDSDIHFLKKKIKNGATYIVTQMFFDNQKYFDFVKKCRKEGITVPIIPGLK
PISTKKQLNLIPHRFHVDLPEDLIIAVVKCKDNKEVRQVGIEWCIEQSKELQKAGIPVLH
YYSMGKSDNIRTIASALF
>A0A7W3UX95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. W1S232|TrEMBL
MTALSFEFYPPKTDDQRAQLERAVRKLKAFAPTHVSCTFGAGGSTLSYTSETVRHLRQGH
GLEAAPHLSCVGGTREEIRELLKLYRALGCRRIVTLRGDLPSGMGHAGDLRHAIDLVEFI
RAEHGDHFRIEVAAYPETHPQAECALSDLRHFRDKVAAGADAAITQYFYNADAYFRFVDD
VRALGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIARRMVAYGDDAESIRAFGAEVV
AGLCQRLLDAGVPGLHFYTLNLAKPSSAVLSQLKLTRG
>B1C148|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] spiroforme DSM 1552|TrEMBL
MKIIDLLHKRPTLSFEIFPPKNYDGDISSIYQTIDELSKLKPDFISVTYGAGGSTTKNTV
EIASKIKNDYNIEAVAHLSCIDASPKQLIKIIDALKENKIENILSLRGDYPKDYDPKNTY
HYFKYASELNEFITKNYPDTFCLSGACYPEVHQEATSLENDLDALKKKVDAGAQYLITQI
FFDNNYYYRLLREARIKGINVPIIAGIMPATNSKSLLKIAKLSGSNIPYNLSAMIERFKN
NPKAMKEVGINYAVYQIIDLITNGVEGIHIYTMNRPEIAKEIIARIDNILKEFIND
>K1SIW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|human gut metagenome|TrEMBL
EKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIKPFAKLSQLTVVPKTFHCD
IPEELAQEVLKCKTDEDAKQLGIEWTTAQVQDLFEHGYNNVHFFTVSAVDSVKQIAKILF
>A0A8H7IHG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKVTEKIQQAEKDGRIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSELVKTCQGVIVDVALREAKANGCRNILALRGDPPSGQEEWTTVEGGFQHGIDLVKH
IRREHNDYFDIAVAGFPQTIQLPEAEAKQEMQWLKEKCDAGANFIFTQMFYDADMFIRWV
KAARDAGITVPIVPGINPIQTWNGFIRATTLSGTDIPQDLMDILEPHKNNDEKVRELGTK
IVSDLCRKILDAGIGIKGLHFYTMNLEKGTKMLLEELNLVPRVETIKPLPWRQSLTPTRR
TETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELDGYGIWIKQTVREIEWLC
PVHQVCTQQIKALPWSDQPPTTEMLVIGQQLARMNELGYLTINSQPAVNGARSDDKAFGW
GPKNGYVYQKAYLEFFVHPSQLHALIKRIERDTNVTYYAINKQGDLKTNSTSEGPTAVTW
GVFPGKEVIQPTIVEAVSFMAWKDEAFELGCQWAKIYEPESPSRKLIENMMDEYFLVNFV
HNDFHDREAIFRPFFADAGLQTNGDTETPAVNGVKHVNGLVNGHSTAVRA
>A0A358LDU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp|TrEMBL
MHIGELIKKQEKPFFSVEFFPPKEKEKWNDFFQVVEKIKAINPLFASVTCGAGGSGQDNT
VEIASAIKNNHGIECMAHCTCVRSDKAKIDEYLSELRHANIENILALRGDKPKNAEGLVD
ESLMSHDFKFASDLVGYVREQHKDFDVAVAAYPAPHPESKTFSEDRKFLVEKIRKGANFG
ITQLFFDSREYLDLQERLKKEGIADCPIIPGILPIQSLASIKHTLSLCGANIPGKFFLAL
EKAYDEGGNEKVKELGLKYAVDQIRILLDSGAKGIHLYSLNKAELCLQLVDMI
>A0A1S7HIM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygosaccharomyces parabailii|TrEMBL
MRISEKLQTQHSKSEKPTFSFEYFVPKTTQGVQNLYDRMDRMYQSTLPQFIDVTWNAGGG
VLSQLSTDLVETSQSVLGLETCMHLTCTNMPVSQIDEALESARLSGCQNILALRGDPPVN
QESWKPVEGGFRYAKDLVKYIRTKYGDHFDIGVAGYPEGHPENVNDKETLLDHLREKVDA
GANFIITQMFYDADIFVKWCEDVRAMGIQVPIIPGIMPITTYTAFLRRAQWCDIHIPQEF
IDKLDPIKDDDQLVRDVGTDLVVSLCRRLLESGHIRHLHIYTMNLEKAPQMILDRLGLLP
THDEPLDNHLAILPWRKSLNPQRRNEEVRPIFWQRRPYSYVARTSQWAVDEYPNGRFGDS
SSPAFGDLDLCGASLIRQSGKRSLELWSTPTSIQDIAQLVINYLRGELKCLPWSDTALNH
EVDDILPDLVALNQRLIITVNSQPQLNGVKSSDPVYGWGPRDGYVYQKQYLEFLLPKDKL
PKLHEALANDVMLTYFAVDYEGNLTTNHRDGSRANAVTWGIFPGREVLQPTIVEKVSFLA
WKEEFYHICQEWKLNFENHQYNDSVNVLQRLINDYVLVNIVDNDFISSESRIFQLLSSI
>A0A1B9KT64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMSKILHELKCAGIDNVLALRGDISPNVQPKNDF
RFASELVSFIKENGDFNIIGACYPEGHLEAATLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKARDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKSA
>A0A3D4Y5S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp|TrEMBL
MRLTELLKTDQVTISCELFPPKQGAQLANYKNIVADMAALKPAYMSVTYGATGGTSDYTV
ELASEVEKHQIPALAHLTCASSTKEKVASVIEELKEKQISNILALRGDIPQNADFPLPNQ
YRHASELIADIKAQGDFCIGGACYPEGHPEADTIFEDLDHLKEKVDAGCEFLTTQMFFDN
HILYNFLYKALSRGIDVPVVAGIMPVTNKAQIKRIVSLSGNMVPPRFLAIVDRFGDNPAA
MRQAGIAYATDQIIDLIANGVNHVHIYTMNKPDVAGEILDNLSEIYVRA
>A0A3N5EGH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buttiauxella warmboldiae|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRIGLEAAPHLTCIDATREELRTIAQDYWNSGIRHIVALRGD
LPPGGGKPDMYASDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNYKQAHKFATMTNVRVPHWMAQMFE
GLDNDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A099TKJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. MIT 05-5293|TrEMBL
MSEPKPCFSLEVFPPRNTDDSRKIYEVLEDLSHLQPDFINVTYGAGGSKNSDKTLEIVSL
IQNHYHIKAIVHLPCIHKSQEEVLDFLDSCTKIGVKDILALRGDKVENAPVSKDFTYASD
LVRFIESHKAFKFEIYGACYPEKHSQALDWVSDMKALKIKVDAGVSRLFTQLFLDNDDFY
AFKEKCALVGINVPIHAGIMPIINVAQARKITAMCGSKIPPKFERILQKYADKPKMMCEA
GTAYAVDQIVDLLTRGVDGIHLYVLNNASVARKIYESIHCLLGRSS
>A0A2S0LXT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia sp. oral taxon 368|TrEMBL
MTQLPDPDPTDGGRHPSIVERIATSTTPRVPFSVEFYPPRDEAAEERLWRAASVFSELGA
AFVSVTYGAGGSTRDRTVRVVERIVRETDLVPIAHLTAVGHTVDELADMIRMYGEVGVSN
ILALRGDPPGDPLGEWTAHPEGLRYAEELVRLIHEVGDFHVGVASFPEGHYRARDLDHDT
EVLVGKLRAGAEYSITQMFWDVEHYLRLRDRAIAADPEQGAKPIIPGLMPVTSLRQVKRM
VELSGCALPDDLAERLRTAAGDGPEENREAVREVGIDLTTRMCERLIAEGVPCLHFNTLN
FSRATREVLTNLSMAPAPGVATSRI
>A0A8C7ED74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothoprocta perdicaria|TrEMBL
MVNENQHTCSASSSSKSDGGSSSGSESSKESSRCSTPVLDAERHERLREKMRRRQDSGDK
WFSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPVGEEWQEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAENYEADQRHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATIEVLKRLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWSSRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKALKKYETRVNY
HIVNVKGQNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFKLLNSPKEQ
>A0A7C7UQG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MNTNTPSKLEKILAAGHLAVTSECGPPRGSDGEFVTKKAKMIKDHVDAINVTDNQTSVTR
LCSLAACIHLKLMGVEPVLQMVTRDRNRIALQSDILGAASFDIYNILCLSGDHQIFGDNP
HGQNVFDLDSINLVQTVRFMRDEAKFLGGEDIQRPPKMFVGAAANPFADPFEIRVRRLAK
KIAAGAEFIQTQCVYNVEKFESWMKMARDRGLHEKTYILAGVTPLKSAGMARYMKNRVPG
MDVPDGIVKRMSGVPKEKQPEEGIKICVETIQRLREVEGVRGFHIMAIEWEEKVPEIVER
SGLYPRPEVV
>A0A6G3LA01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. V31_P5A7T61|TrEMBL
MGYTHASHIDALNQSIAEVSDINVSFEFFPPSTPQMEETLWSSVHRLKELKPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDASREELITIADDYWHNGIESIVALRGDI
PPGGGKPEMYAADLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDIESYLRFRDRCVAAGIDAEIIPGILPVSNFKQAARFAAQNHVKVPQWMAKQFAG
LDDDPVTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPIAVA
>A0A7C5Q4V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKSGSNLERVLTEGHFAVTGELGPPKSANAEVVREKARILKGKVDAVNITDCQTAIVRMS
SIGAGTIVQAEGVEPVIQMTCRDRNRIGMQADILGAAALGLKNLLCLTGDHQKFGNHPGA
KGVFDMDSIQLLGMARGMRDERRFQCGEEIKSHEPRFFLGCAANPFAGPFEFRAARLAKK
VQNGADFVQTQIIYNVEKFAKFMEMVRDLGLHERCYILAGITPPKSLGMARYMKNFVPGL
DVTDEVIKRLQGAKDKRAEGIQIAVDLIQQVREIEGVAGVHVMAIEWEEAVPEIVERAGL
LPRPFAEETPAAPVEEEAAEEAREAIEVTDMAAVKAEADEILAAAKREAEALIARAREEA
AALRAAGPTTTEPATADTQDFDEAGED
>A0A1V4YQV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomethylovorans sp. PtaU1.Bin073|TrEMBL
MPAAFRDKLQSDRFIITTEITPPKGVETSSFLTDAEQLKQYVDAFNVTDNQRAVMRMNPV
AVGKLLKDAGHETIVQLTCRDRNRLALQSDLLGAWALGIRNICVMTGDHTTKGDHPGTKP
VYDLDSVQLLDTVKKLKEGYDLSGNRLEQSPDFLVGAVSNTDPSQPMQHIKLRKKASIGI
DFIQTQAVYDTEEFASFLQKVSDIHVPIIAGIIPLKSAKMARYMNSNIPGIRVPEELITR
MENAEEPASEGMEITSQIIRELKNMCRGIHLMPVGQHTHTREILKMSGLTEGRTHNE
>A0A239J4E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulicella rosea|TrEMBL
MRQGAGSMGREMMATAVETVEKDGQNEGQGRFQSSFGRLFAAAAALRGRTILCDGAMGSM
LYGCGIFINRCYDELNLSQPEVVRGVHNEYLQAGAAVIETNTFGANAVRLKRYGLEEKVH
EINRAGAGIARACVEAHREKMASEAYVAGAIGSLGVRVGADGELSADDAYAAFAAQIRGL
AEGGPGVGADLLIVETMMSLAEAEQAIRAAKSEAPELPLIVMMTVDERSNCLDGSTAEVA
AERLTAWGADAVGCNCSSGPVVVLAAIERMRSATTLPLAAMPNAGTPRQVDGRSIYLDSP
EYMASFAKKFVKAGATIVGGCCGTTPQHIKAMRGALRALEAQEVGVESVKAGPAPNARPG
IEPPPLKDRSLIGSLIAGKKFVTMVEIVPPKGIDCTRELEGADVLHKLGVHAINVPDSPR
ASARMSAQSLCVQIQQKVGIETILHYTCRDRNILGMQGDLIGASSIGLKNILCLTGDPPK
MGSYPDATAVFDVDAIGLVKIVEGLNHGLDIGGNPIGASTGFTVSVAANPGVPDIDNEVR
RFAAKVEAGAEFGITQPVFDLRLLEQFLRRIEQFRIPIIAGIWPLTSLKNAEFMKNDLKV
SMPTEIMARMAAAETPEESREVGIAIAREMLEQSRGHVQGVQVSAPFGKYKAAAEVIGVL
>A0A7Y3GIN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MPTPFKEALESGKFVVTSEVAPPKGTNLEKFKHHIELLKDKVDAMNVTDHQSSVMRYPSL
GGCLLVKELGGEVILQMTCRDRNRLALQADLLFASYQGVQNVLCLTGDSVMLGDHKEAKS
VFDLDSSQLLKTVRTLEKGKDLGGNDLDGAVSFCAGAIVTPEADPLEPQLIKFEKKIEAG
AEFIQTQAVYDLDKFIEFMDYARQFKTKILAGIILLTSAPMARFMNKNIAGVFVPQDLVD
ELASAPKGQALTKGIEIAGRMIKRIHEEKMCDGVHI
>A0A7V4T5D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
SDELLNSKNFVVTLELVPGRESFGRSTDTLIGIAKDAFADGRVSAVSITDNPGGNPSLSP
DVLGYEIFKHGLDVIVHFACRDMNRVGMESRALQLARMGMKNILALTGDYNGKGFGGQGT
PVFDLDSVLLNAMFKTLSKKIVASGDPEEFFTGCAVSPFKTTEAETHAQYKKLDKKIEAG
ASFVITQLGYDVKKFHELILYHNAKNKEIPAMASVYLLSPRSARAMNRGKVPGAYVSDDL
FNKIILEWKDTRQGLKAAVERTAKLGVILKGLGYRGIHIGGIHRSFKTVGVILDRMEEIE
DNWQEYLNEFENRDGNSYYYFDKRTEPVEKRPVMNRIKEKFADHYPYKILNQAHGYFFDK
KAGLSPVYKRIATFFERNNKAWLLKRCLEDPMKVFFLSCQSCGDCSIQHVAFQCPESGCP
KHTRNGPCGGSRNGYCEVYPDRLCIWVRAYERLKNANSLTGFLKDTVPPRMWELNKTSSW
INFHLGKDHQK
>A0A7C3LAH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKSASRLEQVLKGGHFAVTGELGPPKSSDIEVVRNKARFLKGHVDAVNITDCQTAIVRMS
SIAAGLAAMAEGVEPVIQMTCRDRNRIGMQSDILGAAALGAKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQMLGMMRSLRDDQQFQCGEKIKDCPPRLFLGAAANPFAGPPDFRAARMGKK
IANGADFIQTQIVYNVEKFARFMEMARDLGLPEKAYILAGVTPPRSLGMARYMKNFVPGM
DVPDAVIDRLRGAADKEDEGINICVDIINQVKEIKGVAGVHIMAIEWESAVPEIVSRAGL
DQRPVIEDLIIAPNLTTPETIVVQGSAEAAAVVEEVTETAAPEAADLGEEILARARQEAS
EIVAAAQAQAAEIGTDRKVVQTTDDAGEHIMNEKERVMALESVKMGLDALKHAYGLNDDQ
FNALVKFISAQEILVKEPPVAETAAPVAPTPTAPAPPSPVAPVSTPPAAVEDTKAMDEAK
EAAAAKEAEEAQKAADAKAAEEAKKAADAKAAEEAKKAADAKAAEEAKKAADAKAAEEAK
EAAAVREAEESKKAVAAETAAPAVPTLELEKIKLAERASKIAPDNYTQAYNGVIRETVLG
NGDNSVTVGGSKALPFQLFEGEIPHKQLIAMDVVDAGYEEWPEPLSRHFADVLGNPVAWA
QKCVKEYGADALCISLASTDPNGLNRDSAEAAKTAAEVIQAVDVPIIVWGCGNSDKDTDT
LRELTAEIGDKKVCLAPLSDANYRSLGATAMAFQHPIVAASPIDVNLAKQLNILLENLGV
SLDTVMMDPSVGALGYGIEYTYSVMERIRLAALTQQDEKLQVPIICNLGREVWKAKECRL
PTDELLGDQERRGVMMEAITAACMLLCGGEVLIMRHPRAMDLAKELINSLLG
>A0A2U3LWJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfosporosinus infrequens|TrEMBL
MEKAKVRDLKSKFRHGDFVFTTELGAIEGTQIEDRISKAKDYVGLDAINVHDCPNGNLRM
NSVMAASILKRELGIEAIPHYTCRDRSLLGTQADLLGAHALGIRSILATTGDVPQHGPYK
GSKAVYNYNSYELIKLIRNLNSG
>A0A7Z9XF90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MSLKEALESGKFVVTAEVAPGKGTDVEHLLEDAAVIKERVDAVNVTDLQSSVMRLGSLAF
SHFLTEIGIDPVYQVTCRDRNCLALQSDLLSAWALGIKNVLALTGDHPVLGDHPKARPVF
ELDSVSLLDVIGKLNSGVDMVGNELKGTPNLFPGAVVNPGADNEAALDLQIMKLEKKVEA
GAKFIQTQGVYDLDSFEKFMKRIAGLDTKVLGGIILLKSVGMARFMNKNVSGVFVPEPLV
QEIKAAEDKAQASKDIAVRLIKGMKDFCDGVHIMALGWESKIPAILDEVGL
>A0A1S9ZW66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella caviae|TrEMBL
MQSAASQAAPSHKPKFSFEFFPAKTADAQEKLTQTFDELNTLNPQYFSVTYGAGGSTRDT
TLGIVKNLLARSDTPIAPHLSCIGDSKAEIGELLNIYKAIGVTRLVALRGDLPSGQVNMG
ELPFAVDLVKFIREHSGDHFTVKVAAYPEMHPQAKNFSQDIDNLVAKHHAGAAGAITQFF
YNPESYLYLRDKVAARGVDLDKFELTAGIMPITNASNLIRFADSAGADVPRYIRKQLAEY
GDDSKSIRAFGFEVVLKLCEHLIREGVPSLHFYTMNKVKPNKELVEALGLV
>A0A1G9YDM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium phyllostachyos|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTEEMEKILWASIERLAPLQPSFVSVTYGAGGSTR
ERTHNTVARMVRETSLKPAAHLTCVDASREEIDAVVQSYWDAGVRHIVALRGDPAEGVGH
AYRPHPEGYASTAELVEGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQA
ITQFFFENEIYLRYLEKVRAAGITIPIIPGILPVQNFKQAANFARRTGASVPYWLAARFE
GLDDDKETRRLVAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AAKAAA
>A0A1B7IGG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buttiauxella brennerae ATCC 51605|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIAQDYWNSGIRHIVALRGD
LPPGGGKPDMYASDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNYKQAHKFATMTNVRVPHWMAQMFE
GLDNDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A2X4U5I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leminorella richardii|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPSTPEMEQTLWQSIDRLKTLKPKFVSVTY
GANSGERDRTHGIIKGIKDKTGLDAAPHLTCIDASREQLLDIAKDYWNSGIRHIVALRGD
LPQGGGKPDMYAADLVELLRGVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPQWMSQMFA
GLDDDLETRKLVGASIAMDMVKILCREGVKDFHFYTLNRAELSYAICHTLGVRPA
>A0A291P730|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas beimenensis|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGRFAVTTEIDPPDSADPAEVLRRAAIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYATILQMSCRDRNRIAMQGEILGAAAMGAC
NLLCLTGDGVQAGDHPEARPVFDLDSLSLLGIARRMRDEGRFESGRAITEPPRIFLGAAE
NPFVPPAAWRARRLAKKVAAGARFIQTQYCFDVPRLRDFMKEVADLGVLEGPDRAFVLVG
MGPLASARSARWIREHVPGIHIPDAVIRRLEGARDQRAEGERLCCDILAEVREIEGVSGA
HIMAYRQEATVARIIEETGVLEGRVPWYPGRDDPCELNPEAPDAAPCHLTAAGPK
>Q7UNJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)|TrEMBL
MICLMTLASVYQSTDCAISFELFPPKTSEGVELLCKNVERLMQFGPKYFTCTYGAGGSSQ
GTTLEVLQKVKQITKLPVASHLTCVGSTVKELEAYLTEAGRIGVDYIVALRGDPPKGTTQ
FEVTEGGLKYANELVELIRGRFGDLGIAVAGYPETHQEAVDFQTDLTNLKRKVDAGADIV
ITQLFYDNDDFYRFRDACEKVGIEVPIVPGILPVTNFKQAKRIASMCKAAIPQSLESAMT
EADDDQDQFRVGVEHARQQTIDLVNNGVPGIHYYVLNKSEAAAELLDGLSLTSC
>M3EGN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces bottropensis ATCC 25435|TrEMBL
MRDMLATGRTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSVTYGAGGSTRAGTVKA
TEQIAADTTLTPVAHLTAVSHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWIAHP
QGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSPDWDSDVARFVDKCRAGADYAITQMFF
QPESYLRLRDAVAKAGCETPVIPEVMPVTSVKMLERLPQLSNAAIPNALKERIVTAKDDP
AAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGPHHPSRA
>A0A1F3ZQH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_62_17|TrEMBL
MSHPTSTGAELSFEFFPPKTAQGSEKLRAVWTQLAEVKPRFFSVTYGAGGSTRAGTLDAV
RAIRSAGHEAAPHLSCVGATRGEIEAILEQMRTSGIRHIVALRGDLPSGMAAAGELAHAC
DLVALIRKATGAHFRVDVACYPECHPQAKSARDDLMNFKRKVEAGADAAITQYFYNADSY
FRFADECAAEGIAVPILPGIMPIGNFSQLARFSDACGTEIPRWLRLRMQGYSDDLASIRA
FGLDVVSALCERLLAGGAPGLHFYTLNHADLVMEICKRVSARI
>A0A4V3GV70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum visakhapatnamense|TrEMBL
MTAPRVSFEFFPPQSLEASFRLWEAAQALAPLKPAFVSVTYGAGGTTRKLTHEAVQTIHT
HYKLNVAAHLTCVDATRAETLEIAEAYAAAGVTEIVALRGDPPKDQGAFRPHPEGFANSC
ELIEALAATGSFRLRVGAYPDPHPEAGSADADVLWLKRKFEAGADSAITQFFFEAETFFR
FRDACEKQGIDGAKIIPGILPIEKWAGVRRFAERCGAHVPPGIDAAFQTAIRDGREELLG
KAMATELCTELMEGGVRDFHFYTLNKPHLTRDICHALGVLPEAHLEKVA
>A0A7J9BWM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium gossypioides|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DALVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNFMDGNIFGVFEDL
>A0A7C5SEP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermopetrobacter sp|TrEMBL
MSGQAHNDGIEVSFEVFPARTDTGRAALARLARRLARFKPEFISVTYGAGGSSRDLTEAT
IRALLAAAGIPVAAHLTAARASRADTMAAAERFVGMGVSRIVALRGDAEKGAPAFTPHPD
GFANAAQLTAALRERWPDLPISVAAYPEVHPDSPSREADLDNLKAKFAAGATDAITQFFF
DNRLFTDFLRDTKARGIAGSIIPGVMLIHDFAGVRQFAASCGASVPARLDAAFAGLRPKD
GKEDRAVHDRLAAAIAARQTLDLAAAGVRRFHFYTMNKSAPAEAMCRILKPQI
>A0A7K0F5S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. LC2016-23|TrEMBL
MKVTEHIENAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
IMALRGDAMKDEQYFIPKAGGNDYAIDLVKQISLLNQGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNTKYFEFVAKAREMGITVPIIPGIK
PIAVKRHLQILPQIFRIDLPEDLIHEVDKCKDNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASRIF
>Q2LZ54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila pseudoobscura pseudoobscura|TrEMBL
MFAKFLPTKTYLCFNASSDSYFKTILQVLRSAPGWRCSSASRKASVRRLDCGLPQRSDDR
RAITHTNVKLIRTSAKSIRETVTAADRYSRYQAQFRAICQRVSIFESDCEMHATETVPGI
GLAPISYVPCVHYATHQNGTDHRELRVADLVAERTARRQFFYGIEMVASQEGKPTCLDFN
EFLPVLPTFLSIVWLGATYCSVDPIELVTSLQLARSLEARIPVMPHLSLYCLTEERLNEF
LALNFTNVLPIRGDAVKEGQTFRYTQQVVEHIRRQRGDRISICVAGYPEGYTNLAEPQDP
AEAMRYLKAKIAAGADCIITQMCYRSDTIIQFIKDVRSAGITVPIVVGQLVADSFRTYCL
SENIAGVHLPPGLRSELLAIESDAERVSQFFIQLSIRIIRDILAADVGVYGVQFYTFNQF
APVQAVLKELRTLDILKDEGGQ
>A0A7X8TAE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. P32RR-XVIII|TrEMBL
MALKTGNRRNIGISFEFFPPKSEEMEGQLWNAVAELQDWNPDFVSVTYGAGGTTKAPTLT
AVTRFLNQTPLATASHLTCVGATKDETHQVIDNFRKAGVKHFVALRGDAPGGAGVPYQPH
PGGYANAAALVAGLRAIGDFEISVAAYPEKHPESKDVAADIDMLKRKADNGADRALTQFF
FDNDNFERYLEKVRAAGIKIPIVPGIMPIQNLTQLKRFASACGTVIPAFLDERFAGLDDK
VEERLKVAADVAVEQIEDLVRRGLHEFHLYTMNRSPLVSAVLGNLGLEREGAKRAGAAA
>E0P2T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp. oral taxon 149 str. 67H29BP|TrEMBL
MADIREHLKHEPLVFDGGMGTYYAQKTNTRGKGVELANLQSPDVVAGIHAEYLHAGAQAI
KTNTFAANRIVYQGDDELVAQIIRAGWALAARAAEPFDAYVFADIGPVIGLPPRDIAAEY
RFLADTFLSCGATHFLFETNSSAEGLTETAAYIKAACPHAFVQISFTALPGGYTRDGFFA
EDLVRAVAESGQVDAVGFNCVNGVRQMKELLHHLKSVSLPLALMPNAGHPMVVDGRTFYE
SAPEYFAETLAALVQDGVSILGGCCGTTPAHIRALCTALGTQGTVTADVQAAAEQEPVIQ
AESPFFAALRDGRKVIAVELDPPETGHAEKFLRGARELREAGVDAITIADNPVARARMDA
AMLASRVHRELGIEPIPHMTCRDRNLNAIKSILLGLSAEGIHNMIAITGDPIPTAERDEV
KSVYQFNSRKLSAFIKSLGEHGDVLPFHVFGALNINAKHFPSQIGLAKKKLEAGMTGFFT
QPVLSERAKENLCTAREELGDALIMGGLMPVVSERNARFMASEIAGIHVEERIINAYHGL
DREAAEELAVRLSLEIAHDIEPYIDGYYIITPFSRTPLVARIVAELLK
>A0A7C1LMS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MSNEPVSNLQRDLDSGEFVVTAEIGPPKGTNIAPVIHEAEEFLKGKVSAVNVTDIQTAVM
RGSSMVGAKLLFDAGIEPVLQMVTRDRNRLALQSDLLAAHIFGIRNVLCLTGDHVTMGDH
PQAMPVYDLDSVSLLDAMCKLEAGTDLGADMKGKANELDGVPTFFKGCCVTPCADEVDPQ
VIKLEKKVEAGAQFVQTQAVYEPKVFETFMKKVEHIKVPILVGIVMLKTAGMAKYMNRGV
PGVVVPDAIIQRMTDCEKPDREKVSIEICGELVSTMKDMCQGAHLMTLGWDHCVPGIIQA
AGLA
>A0A264YY56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia aryabhattai|TrEMBL
MGLLEDLQSRILIGDGATGTLLYSHGIDSCFEELNITKKEEIHRIHRAYVEAGADVIQTN
TYAANYQKLARYGLEDAVKDINVAAVQIAKQAAKKDAYVVGTLGGIRSFQKNAISTEEVK
RSIREQLFWLLNEGVDGLLFETYYDFEELKTVLSLARKETSKPIITHVSLHDIGVLQNGA
SLYDAFQELESLGADVVGLNCRLGPSHMIQSLEEVPLLNRAFLSAYPNASLPAYVEGKVE
YATNEDYFVESAKAFRNQGVRLVGGCCGTTPAHVQAMSQALKHEKPITQKTVKIRPLVEI
KEQEQTKEPHLHDLVKERRSIIVELDPPKQLGPTKFLEGAKALHKAGVDAVTLADNSLAS
PRVSNLAMASLMQQQTDARPLVHITCRDRNLIGLQSHLMGLHTLGINQVLAITGDPSKIG
DFPGATSVYDVSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVVRL
EKKISCGAHYFITQPLYSTKQIEEVYEATKHLDAPIYIGIMPLTSARNARFIHHEVPGIK
LSEDILARMDATGEDRIKGEIEGLAIAKNLIDTAYELFNGIYLITPFMRYQMTEILTRYI
NDKQLVTTERKN
>A0A7L1C236|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Illadopsis cleaveri|TrEMBL
MVNETQQTCSGSSSSRSDGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLALWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDELEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A839UXR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endobacter medicaginis|TrEMBL
MNDLAPAQGSASPLERWLTGPRFAGLPAPGAVGVPRLSFEFFPPRTAPVEAQAWAAIQRL
APLAPHFVSVTYGAGGSVQDRTHRMVARILRETTLTPAAHLTCVGASRGAVDDIARRYWD
AGVRHIVALRGDPPPGERFSVHPDGYRDAADLVAGLRRIASFEISVAAYPEVHPEAASPD
ADLDNLRRKLDAGASRAITQLFFDTDIYLRFIDRCHAKGITAPVVPGIMPISNFAKARRF
VASCGASVPRWLDGLFEGLDTDEGSQHLVGAVVAAEQVRLLQANGVDEFHFYTLNRAEMS
YAIAHLLGARPRSG
>A0A4P5XI03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHIADILSRDSMTTSFEFFPPRNDAGWESLFHVIADFERLQPSFVSVTYGAGGSTRTRTH
ELVVRLKTQTKLDPIPHLTCANHTRGDIENILTQYAQCGVSNILALRGDAPLAGNSTSDF
AHAVDLVKCIREFNNRGTHTDPRGFGIGVAGFPEGHPDTPNTLLQMDHLRAKVDAGADYI
CSQLFFDNAAFIDWKERCDLAGIRVPIMAGIMPVTSIAGLKRMAELAGGTRFPAKLLRAV
QRCGDDADAVERVGIHWATEQCMALLDHGVRGIHLYTLNKCAATQAIFQNLGVKNSAQLR
SI
>A0A1H4G8B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sartisoli|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLAPLKPKFVSCTFGAGGSTQQGTLDTVLDIAK
DGIEAAPHLSCIGSSRESLRAILNEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVAF
IRAETGDWFNIEVAAYPEYHPQSRSPSADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSDMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTDLCRRLVDANVPGLHFYTLNGAAATRSICERLGAR
>R9IZU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium A4|TrEMBL
MKLDTILLKNDVTLSFEVFPPKVTANYESVKEAAYGVAKRKPSYMSVTYGAGGSTGGNTL
KLAKGIQEEYGVTTIAHLTCVGATKEGIRQALTQMREAGIENVLALRGDRPKDFEGDPFT
EYHYASELVEDIQAFGGMCIGGACYPEGHVESENTQEDILNLKKKVDAGCAYLTTQMFFD
NNIFYHFLCRVREAGIGVPVIPGIMPITRSSQLQSAVRLSGCNVPMRFRSIVDCFGKNPE
AMQQAGIIYATDQIIDLIANGIKHIHVYSMNKPEVVKGIQESLCKII
>A0A4R5DKS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiangella asiatica|TrEMBL
MTTVLDRLAERRPVFSVEFFPPRDDAEEAVLWTAIRQLEPLDPAFVSVTYGAGGSSRGRT
IRTTARIAGETTLVPVAHLTGVGHSRAELRNVVGWYAGNGIRNVLAIRGDPPGGPAGVWE
PHPDGITHAEEMVRLVGGLGSFCVGVAAFPHGHPDSTDLDTDTQRLVEKIRAGARFAVAQ
ICFEPEQFLRLRDRLAARGCDVPLLPGVMPLTTKRTLTKSVELSGVAAPPELTGWLARYD
DDPSGFRAAGMDMTTRTCERLLAEGVPGVHFYTLNRSTATREIVGRLDLGPARSAA
>A0A246KXI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas pavanii|TrEMBL
MPAGLSLRADAFINAFSLEVSAKAMPALRAEADRIPRGTVISIPYLASEDDDARLAAART
VRALGFEPMPHISSRRIGSAAALARFLERAVGDAGVARCLLIAGDLATPAGPFADSASII
QAGLLEHSGIKVVGIGGHPEGHPVMSSDERWQALEGKCQAIEARGMAPLVVTQFAFDADT
VLAWLDGLRARGISVPVLVGVPGPASIPRLLRYAAMCGVGASASMLARYGISIGRLIGTA
GPEVFVDRLVRGLTSAHGQVSPHFFPFGGIAPSLEWMARYRRRTSGTGG
>A0A5Y8ZLJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALADIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILKKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A4U6MAY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. TBCS-14|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRIIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>G2R3H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermothielavioides terrestris (strain ATCC 38088 / NRRL 8126)|TrEMBL
MHIKDVLAEAERTGEPSFSFEYFPPKTAQGVQNLYDRMERMYNFGPKFIDITWGAGGRVA
ELTCEMVVQAQTYLGLEACMHLTCTDMGEERVNDALRKAYKAGCTNILALRGDPPRDKEK
WEATEGGFRYARDLVAHIRKTYGNHFDIGVAGYPEGCDDNQDEDLLLDHLKEKVDMGASF
IVTQMFYDVDNFLRWVGRVRERGITVPIVPGIMPIATYASFLRRANHMKCKIPDDWLAKL
EPVKNDDVAVRDIGKTLVADMCRKILAAGIRHLHFYTMNLAQATRMVLEELDWLPSPDRP
LKQALPWKQSLGFGRRGEDVRPIFWRNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEQNRKKWGEPTCIRDIANLFVRYLNKEIEYLPWSEAPVAEEAEVIKKEMID
LNKRGLITVNSQPAVNGAKSSHPVHGWGPANGYVYQKAYLEMFIAPELFPEIKRRIENHP
DLTYHAVTKSGNFETNAQSEGPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGTEW
ARCYDPGSPSRLVLEEMMNTWYLVNIVNNDFHRGQTIFEVLEGLEVRDLDKVPQPQVNGT
KSPAADPTNGAETSA
>A0A1B4UZL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurifustis variabilis|TrEMBL
MESQRKHARSFSFEFFPPRDEAGRTKLRETVAQLRQLRPRFFSCTFGAGGSTREGTYDTV
KELQDQGLKAAPHLTCIGTSREFIRELLQAYAALGIDRLVALRGDLPSGLPNTGGDFRYA
TELVEFVRSETGDRFAIEVAAYPEFHPEAASAEDDLEHFASKVRAGADSALTQYFYNADA
YFRFVDECESRGIDIPIVPGIMPITNYKQLARFSDRCGAEIPRWIRKRLESYGDDLESVR
AFGLDVTTELCDRLLRAGAPGLHFYTLNRAGPSCIVWERLGL
>A0A3C1G4Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MGIKELFKERKRGVAFEFFPPKSPKGKESFMQVVNDLKQYDPLYVSVTYGAGGSTREGTV
NTLKWIKQDTNLTVMSHLTGIGATPTSMDMLLRDYMAHGIDNILALRGDPPRNMPGFDLT
RGDFKYAKDLVKFVKKFAYFTIAVAVYPEGHQESPSIEKDMEYTKQKIDEGADFAITQMF
FDNRYYYDFMERAGKIGISIPIFPGIMPITDCRKIEDFADFCSATIPKEIREKMAPLLDK
PGEMAKLGIEYALKQCEDLVRNGVRYFHFYTMNKAAAAREILHGLAGLQ
>A0A242JZ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus sp. 9E7_DIV0242|TrEMBL
MNLSGNNKPSLSFEVFPPSTEATIDSLYSSLHQMEDLRPDFISVTCSNRQLSLEESTVKL
ATHIQKKHQVPSIVHLTAAYSSKEAIDKILASLHQKKIRNILALRGDLDATLTRGTDFLY
AGDLIAYIKAWDQHFSISAACYPEGHPESVNTINDIYHLREKVQAGADQLITQLFFDNEL
FYRFQEKCWLAGIEVPIIAGIMPIVNKRQAERIIRTANVQLPKKFLAILEKYADNPVALR
DAGLAYAIDQIVDLVTQGVSGIHLYTMNQANIARSIYTATHSLFELESREASFIS
>A0A2K8XTF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. ALD11|TrEMBL
MKITEHIKKANGKSLFSFEIIPPKKGNNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYID
KGEGLLDRKITRMRPGTLGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGINN
VMALRGDAMSHQKYFEPSKNGNHFAKDLVTQIKDLNCGKYLHDVIEASNKADFCIGVAGY
PEKHLESPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVAAAKNAGIHVPIIPGIK
PIAVRRHLQLLPQVFKIDLPEALITDIESCKTNKEVRLVGIEWAIQQSKELLAAGVPVLH
YYSMGKSDNIQAIASELF
>A0A1H6BUW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio hangzhouensis|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSTPTMEETLWKSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDASRDELIDIAEDYWANGIKNIVALRGD
IPPGGGQPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAMNKVKVPGWMQKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A4S9J6L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVNNVTVEDHDTPVANGNGDKKAKARRRSSIANS
APQNRVVIDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVE
FFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWL
>A0A3M0MP96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus alkanivorans|TrEMBL
MARTKPSISFEFFPPKTLDASFRLWETARALAPLAPDFVSVTYGAGGTTRKLTHEAVTTI
NRHYGLEVAAHLTCVEATRAETMKIVQDYADAGIREIVALRGDAPKGQERFTPYPDGFAH
SIELIEAIAARGDMTIRVGAYPEPHPDSSGTDADVAWLKRKVEAGATSAMTQFFFDPETF
FRFRDKCEAAGIDAPIIPGILPIQSWSGTKRFASICGTSVPQWAEDAFARVADDPQAESE
LATGICIELCEKLIDGGVDQLHFYTLNRPELTRDVCLALGVKPTRKLEDVA
>A0A3C1G541|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MKSGSNLEQVIASGNPAVTAELGPPMSADPHEVIKKAQLLKGYCDAANITDCQTAVVRIS
SIAAAVIALREGLEPVMQMTCRDRNRIAIQGEILGAAAMGVANLLCLTGDGVQAGDHPQA
KPVFDLDCMSLTEIARRLRDEGKFESGRALTTRPKMFLGAVENPFAPPYDWRPLRLAXCP
>A0A6G9FA64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Tu 2975|TrEMBL
MSTLREILAAPGPSFSFEFFPPKTAQGERTLWNAIRRIEPLAPTFVSVTYGAGGSSRDRT
VAVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGVHDVLALRGDPPGDPNAPWT
AHPDGFNHAHELVSLVRRSGDFSVGVAAFPERHPRSADWDDDVRHFVAKCRAGADYAITQ
MFFHAEDYLRLRDKVAAAGCDTPIIPEIMPATDVKQIARFAQLSGATFPAHLAARLDAAR
ENPAQGHRIGVEYATAMADRLLAEGAPGLHYITLNRSTATLEIHQNIQNSRSAHALAAGR
>A0A6G2UY07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID2563|TrEMBL
MALGTPSTRTDHARTVREMLATGATSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVKATQDIAAESTLTPVAHLTAVDHSIAELRNMVGQFADAGIRNILALR
GDPPGDPMGPWVEHPQGVKYAADLVRLIKEAGDFCVGVAAFPERHPRSEDWDTDIRHFVD
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCETPIIPEVMPVTNVRQLERFSQLSDAQL
PDDLKERILAAKDDPAAVRSIGIDFATRFSAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A6P1CPP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia cyriacigeorgica|TrEMBL
MTFDNVRGRSTPGRPSSTPPIVSATPSVVQSLRLHASRAVPFSVEFNPPRDAAGEARLWR
AVRTFERMHPAFVSMTYGAGGSTKDRTVRVTGELAGETTLLPVAHLTAVGHSVAELRSLV
GAYADSGIRNILVLRGDPPGDPLGEWHKHPEGVEYAEELVRIVRDLGDFHVGVASFPQGH
HRSPDLDHDTRFLAAKLRAGAEYSITQMFFDVEHYLRLRDRLIAMDPVEGAKPIIPELMP
ITSLRTVKRAEELCGRPLPRAVIERLERAAGSGPEEDAAAVRAVGIEIATEMGQRLIDEG
APCLHFITLNFAKATSEVLTNLGYGVTAAPISA
>A0A0K9S1T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spinacia oleracea|TrEMBL
MKVIDKIKAAEAENKSLFSFEYFAPKTENGVENLLETMERMVVQVHAPCFCDITWSTPTA
NVTMEIANRMQNSVCVEAMMHITCANMPVEKIDIALDTIKSNGLQNVLALRGDPPPGEDQ
FVPVEGGFSCALDLVKHMRSKYGDYFGIAVSGYPEAHPSVFGPDGVASPEAYASDLAYLK
RKVDAGADLIFFDTDIFLKFVKDCRQIGITCPIVPGIYPIIDYKGFLRMTGLCKTKIPEE
ISDALERIKDNEDAVRAYGIRLGTKMCKKILGSGVKHLHLYTLNKEESSLRILMNLGLIE
ESTIPTPISQLTPQDAPVSIPTSARMDSEDVEVQKTLYL
>A0A5F1AZU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus petrasii|TrEMBL
MSRLLNQLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADIIQT
NTYGANFEKLKTFGLEHKVKEIHKAAVQIAKRAAKPNTFILGTVGGFRGLKQEELPLSTI
QYHAENQIDTLVEEGVDGLLFETYYDLEELTNIVISTRRKYDIPIIAQLTASNTNYLVDG
TEINEALKQLVECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRIIGGCCGTTPKHIAYIKSSVKDLKPVTSKKVVPINRKS
NHAVSHTYKHNLTTKVKNGPTVIVELDTPKHLDTDLFFENIRKLDEANIDAVTLADNSLA
TVRVSNIAAASIIRQRYDIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGASNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKIAAGMSYFITQPVYSKEKIKEVYEATKYLNTPLFIGIMPIVSYNNALFLHNEVPGI
KMSEDILNQFKAVKDDKEKTKALSLRLSKELIDTVHEYFNGLYIITPFQRIDYSLELAAY
SKAITQNKEAIS
>A0A7U6HB37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus anthracis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDVSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1F8N8E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_56_8b|TrEMBL
MKIGDIIKARGRSLSFEFFPPKDAATEARLFQTIATLKGYRPTFVSVTYGAGGGTLRNTR
KVIVRIKEETSLTPMPHLTCVEQSHQDLDNILKDYKRHGIENVLALRGDPPKGTDKFVAH
PDGYCYAIDLVRLVVLVGGYSIGVAVYPEGHAEAPDLETDMYYTKQKINAGADFAITQMF
FDNRFFYNFMERADKAGITIPIIPGIMPITDIEKIKRFSQMSGATLPRSIVAPMEKAASP
EEVRQLGIEFATKQCENLSQNGVKYFHFYTLNQSRAVTEIVNNLGFAKKAPQP
>N6WBY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schaalia cardiffensis F0333|TrEMBL
MTPPDEAYATPCTHEHEPSLISFEVMPPRVPSAAPKFWHTIDELLTARPDFLSVTYGAGG
KDRSSAREVVAELARNAPVHPIAHITCVGNSTVDVLDAVADALDSGTRTFLALRGDPPAD
DPDWEPEAGGVRSAIELIHLIRTVEKRRCDYHPAEALRAAFAPLTIAVAAFAAGNPAAGT
SPQQEAERLLLKQAAGANFAITQLFWEADTYLSFVERCRRLGVTIPIVPGILPPTELARL
KRVTELSGIEVPPHIVDTLSGAQDPESRHELGVGLAASLADEVVKGGAPGVHLFTFNKAR
PALDILSRLGHGPTPFPESGRLGASVTE
>A0A285E9X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus sabuli|TrEMBL
MTGTVRDLLAHGRPTWSFEFFPPKTPDGAAQLWTALRELERLRPSFVSVTYGAGGSTREG
TVSVTERIATETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WVAHPEGLTYAAELVDLIRSMGDFSVGVAAFPERHPRSPDFDSDVEMFVRKCRAGADFAI
TQMFFRAEDYLRLRDRVAGRGCDVPIIAGVMPVTNARQITRIVQLSGQAFPAHLAARFAQ
LDGDRPEDKAAVRAYGVEVATQLCRTLLDEGVPGIHFITMNRSTATREVYANLAAVPATH
>W7IPY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinokineospora spheciospongiae|TrEMBL
MTERLRTDRPVFSVEFMPPRDEADERRLWKAVRELEGLDPAFVSVTYGAGGSSRDRTIRT
TGRMATETTLVPMAHLTAVDHTVAELRNVIGWYAAHGIRNVLALRGDPPGDPNGPWVSTP
GGLNYADELVALVRELGDFCVGVAAFPYGHPGCTDLDADTDNLMRKFAAGADFAIAQLFF
QPEDFLRLRDRVAARGTDKIVVPGIMPLTTPKMLYKTVELSGAPLPPHFAARLEPLAEDA
KAFRAEGIDLITETCQRLLAEGVNDLHFYTFNQSKATREVVGRLGLVPTRA
>A0A2V1H0X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibaculum spongiae|TrEMBL
MKANTMSNTQSAKLTDFSLEMTSRDIGSIPQVAASISNNTQVKIAYLGNETMKQRLDAIE
ALNKHSLEPMPIISARRITSPAELESYLSQAKKVAAIESLFLVGGDPSAPQGPFSDSLEL
IQSHCIEKFAIKNIGIAGYPVGHPKVHNDILWAYLKQKHSELVARGFSVEITTQLSFDAE
GVINWIEQVRQANIDAPIRIGVPSPTTLTGLMKFAKQCRVSTSLGLLLQYGWKVSSLLGN
IGPESFLEIIQERLQQLDLGDVRLHIYPIGNLVNAVKWANKNL
>A0A3D8QLM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coleophoma crateriformis|TrEMBL
MEKITDKIAALPPDSNYFSLEFFPPKTTMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
SAKSLELAELCQRELGLTTCLHLTCTNMSRTLIDKALEEAKVLGIRNILALRGDPPRNDE
YGTIEDKAGQSPAQLEDFEWAVDLVKYIRKQYGDYFCIGVAAYPEGHADELHPLGQSFEH
DLPYLVEKVKAGADFIMTQLFFDAESYDHFEKTLREHPSGAFKDIHIIPGMMPIQSYQMI
KRTTKLSHAKIPSDIMSRLDEVRGDDEMVKKVGVDVVSEIVSHIKSSKIPAPGPRGFHFY
TLNLEKAVSFILERTNLIPEPEIADEIAIVDVPLQTLSINGSTNLSVPESRSRSMRRQSS
VGSDPYNRVIISAARASNPDYEATAEEASIPAESINTRANTLAISEGEGSLGREATWDDF
PNGRWGDARSPAYGEIDGYGVSLHMSVNQAIKLWGHPTSIADITDLFIKHIEGKLTAIPW
SEEGLNEETNSIKAQLTALNQKGWWTVASQPAVDGVRSTDPIYGWGPKNGFVFQKAFVEL
FLPSSDWKALHAKLDSLGDDVSYYATNASGDFVSGGCAEEGSTNAVTWGCFTGKEIITPT
IIEEVSFRAWAEEAFGIWAEWSRVYPPRSASKALVEQVRDDVWLVNVIYHGFKETEGLWN
LLLN
>A0A1G3M400|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium GWB1_59_5|TrEMBL
MSSVLKALAARPRRISIEVVPPSRGGDPDGVIACVEAVAPYEPAFVSVTDHPAGRAWEER
EGRPVAVPIRGKPGTLGLCVAIRERTGSVVVPHVVCLGSDRFKAEDQLIDLRYAGFSDVF
IVRGDERFTPFAQKTDAAKASTESAGALPHAVDLVRIVAAMNAGDYLSDGSRGSPAGLSV
GVAAYPEKHPSSANPESDLASLVEKANAGAAWIATQMVFDAARYKDFVARARAAGITAPI
IPGVKPLVRLRSLAGVPGTFFVDVPQELAKALSEARTPTEERLVGVRHAAALVEALFDAG
APCVHFFTMGKARDAVETLSAVFGAKSGSSL
>A0A3E2YNQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. MW-13|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTPRGEQLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVR
GDPPGDPGGEWVRHPEGVLYAEDLVRLVRDAGDFSVGVAAFPYKHPRSADVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQLSTIERSTQLSGAPF
PPALAARFAEVADDPEAVRRLGIEQAAEMCRRLLDEGVPGIHFITLNRSTATREVWQQLQ
VGTRV
>A0A1R3W292|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodosinus mongolicus|TrEMBL
METQKRFERTFSFEFFPPKNPESAARLRDTWTQLAALGPRFFSVTYGAGGSTQARTLETV
LEIHRQSGVDAAPHLSCIDSSREQMREILQTYQDAGLKHIVALRGDLPSGMHDPGEFRYA
NELVGFIREETGDHFTIEVAAYPEFHPQALSPQKDLWHFKQKVEAGADSAITQYFYSADA
YFRFIDDVTALGVNIPIVPGIMPITNFSQLARFSDACGAEIPRWIRQRLQHFGDDKASIR
SFGEAVVTQMCERLLDAGAPGLHFYTMNQVSPSMAIWTNLGLAGAETE
>A0A8F2LDP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] haemuloni|TrEMBL
MSTVLNKIQALQPGERFCSFEFFPPKTDAGFRNLLARLSRMMALNPLFLTITWGAGGSTS
EKSLDLAATCQKELGVTTVLHLTCTNTNKEIIEDALKRAREAGIKNILALRGDPPRAEEY
WTPNCDFNNAVDLVRYIREQHGDYFCIGVAGYPEGHVEGADASDQDPRKDLPYLIEKVEA
GADYVVTQLFFDVDKFVAYEQLLQETPQLKNIVLIPGLMPITTYRVFIRSTRLSHASVPK
TILEDLNAHANDDDMVKVIGLDVLTKMISEIDARTNGRVRGYHFYTLNLEKAVASIINRS
PVLQNMIPHNQSVQHDDAIASDSDDDLPVVPQKNGRRKSSVNENSVAVPGTAEAKRALVS
KALSKDPKAIVDISTGKGALGKDATWDEFTNGRFGDSNSPAYGEIDGYGPNLKLHSNKEV
EETWGEPKSVSDITKIFVDYLSNKINVLPWADSELSPETALIQEELFELNERGWFTLASQ
PAVNNCSSRDKILGWGPSNGHIFQKSFVEFFIPKKQWHDDLLPRLASQVDDKTITYYCGD
ASGHISSNLPLSIGKNSNSKSAVTWGVFPSKEVLQPTIIDYESFRAWNEEAFLLWLEWAR
CYRKDSASFQLLNDIYNSYYLVSLVHHNFTDEFVLWTTLLSD
>A0A1T5DSW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salegentibacter holothuriorum|TrEMBL
MKITEHIKKAKGETLFSFEIVPPQKGKNIQDLYDNIDPLMEFNPPFIDVTTSREEHLYIK
KNNGLLERKITRMRPGTVGICAAIKQKYHVDTIPHVLCGGFTREETEYLLVDCHYLGIDN
VMALRGDAMKHQRYFEPTDGGNCYASDLVSQIKNLGAGKYLNEVIESDNNADFCVGVAGY
PEKHLESPSLTTDLKWLKAKVDAGADYVVTQMFFNNQAYFEFVDKAREAGINVPIIPGIK
PIAVKKHLQLLPQVFSIDLPEELITEVEACKDNKEVRKVGIEWAITQSRELKEAGVPVLH
YYSMGKSSNIQKIAEAVF
>A0A6B0H6Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharibacillus sp. WB 17|TrEMBL
MGLLDELRTRVLVADGAMGTLLYLNGIDRCFEELNLTRPEQVRQIHQAYLGAGAEVIQTN
TYAANDHKLKRYNLEYELEAINRAGARLARSAAEGTGAYVLGTIGGIRSTKPGEVTLGEI
KRSNERQIESLLSEGVDGLLLETFYDPEELRSTLTLARQKTDLPIVAQVSTQDSGFLQDG
STLTEMFAILEGLGADVVGLNCRLGPFHMTRYLKQVPLPKHAFLSAYPNAGLPEYNEGRL
RYRSGADYFGRSALELRGEGVRLIGGCCGTTPEHVAAMVEAVKGAAPITEKTTERSDDAE
PVPFGRIEVREKAEQLSAAQEGPPAEIPFHAAAAAKDHSVIVELDPPRTLRTDGFFKGVQ
ALKEAGIDALTLADNSLASPRIANESLASVVKEKYGVKPLVHVACRDRNMIGLQSHLMGL
AASGINQMIAITGDPSKVGDVPGATSVYDYNSFDLIKLCKQFNEGRLPSGRSLGLRANFS
VGAAFDPNGRHLEKGVQRLEKKIAAGADYFMTQPVYDERRIEELYHATKHIKQQIFIGVM
PLISSQNAAFLHNEVPGIRLTDEILARMQRHEHDKEAAMQEGMAISRSLIDAILEYFGGV
YIMTPFLRYEQSAELTRYVHEAAGKRALIQSRPAR
>F7V646|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. (strain SY8519)|TrEMBL
MPDKYTCEVEMNPPKQNSQKLEEDLATFAERFERVMESGFVASITDNAMGILHFQPHEMI
EELDLKPRENQVLIHLNTFHTKEVLDEILAFGKSHNITNFLCLSGDGSDKMHKLEPEELE
APEVPVTTSVELIRYIRKYYPEFHLGAAFNPYEPEEKEFAKLKRKVEAGAEYIITQPILG
RNPLVDRVMREYPDLPVVIECWMSKKVYLLSEVIGETIPEDTVYDGYEKLLELQKEYPDS
GNYLAMMGFKKTYPRVEELWKTRGAS
>G5GES0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Johnsonella ignava ATCC 51276|TrEMBL
MINIRDFLKRRVLLFDGAMGTYYARISGDMSLGCEQANIKRPDIIRNIHREYIDAGAMAI
KTNTFGLSYFDTSHEEIQKRNELISAGYDIATEAAQDKAYVFADIGPAAGASESETADIY
ISQAEIFLKKGALNYIFETLSGSEGILKAAEFIKNLKPSAFIIVSFAVLPDGYTRDGRYY
KDLIEKMQKSSVIDAVGINCISGAGQMYELVREFDLLRIFESGKYLSVMPNAGYPVIRGN
QSVFDGNDAYFASKLKQIYSYGVRIIGGCCGTTPEYIKKVAQDLSGEAPKSVFVEKIKPE
SHKSIKKYTNVFLDRLKTWKDTSKKVIAVELDPPKDGDAQLFLQNAKRLKDIGIDILTIS
DCPIARARMDSSLLSCKIKRELSMEVLPHLTCRDRNINATKALLLGLYSEGVHNVLAVTG
DPVPTAERSEVNAVYQFNSRKLASYITSLNKDIFNDSIKIFTALNINSKNFSAELKRAQL
KIECGSVGFLTQPAYSQESFENLKMARCKLDALILGGVIPLISKRNAVFMHNEVNGISIP
EDIIDSFENLTPDECKKHAIKLCLDVAARMYEDVDGYYIITPFQKIDIIEKIISGIRQGV
NDYGLR
>E1QJ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfarculus baarsii (strain ATCC 33931 / DSM 2075 / LMG 7858 / VKM B-1802 / 2st14)|TrEMBL
MKAGSNLEKVLRAGHFAVTGELGPPRGNHADEVRKKAAHLLGAVDSVNITDNQTAVVRMA
SWAACKLILDQGLEPNLQMVCRDANRLGLMANILGATALGIKNVLCLSGDHQRFGDHPEA
KNVHDLDSVQLLATFKKMRDEKKFLNDKELEGAPEIFIGAAVNPFGDPFAFRVSRLANKI
KAGADFVQTQCIYNMDKFREYMKRAVDRGLHEKCFILGGVTPLKSVGMAKYMAKFVPGMD
VPEALIKRMQGVDKKDQAAEGIRICIEAIGQLREMPGVAGVHVMAIEWEHRAREIIDGAG
LLPRPQL
>A0A5S4FCW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea turkmeniaca|TrEMBL
MVTFELICEIEPPTKPDLTHVRHQIGTLGKIAHSFLIPDNHIGRATVSSVAVAHEVEAMG
GRGIACLNSRDRNLLGFQRDLLTAAAYGVDQFLFVYGDKPTSGNRTSDLTVRSMIEEARR
FSPGLRLGAAAALRPLPAWKRTADFLFAQVSFSLEAQLRWREAHPVDVPVYAGVMVLASE
RHARTLAAAIPDIALPDDLVARVAADRMAGVEAACEQVLALRDSGAFAGVHLIPVSRYRD
VESRLATAL
>A0A1G7YKP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. OV458|TrEMBL
MDNPNFSIEFFPPKTAEGAEKLRVTRAKLSELKPKYFSVTFGAGGTTQQGTLDTVVEIMA
AGADAAPHLSCVGGTRESIRAILAEYKSHNIQRIVALRGDLPSGYGAGGEFRYANELVEF
IRQETGDHFHIEVAAYPEVHPQARSPQDDLLAFERKIKAGANSAITQYFYNADAYFQFVE
QAQKLGIEAPIVPGIMPILNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VSALGERLLKGGAPGLHFYSMNQAAATTALWQRLV
>A0A498BUJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium telephonicum|TrEMBL
MSVHTQERTPSLPATRIAGCPKSMTYGPCGGVNGDGTCEVDPTPCVFLHRDLPIRWSAEP
PAGGPAEVATTAGRELSAIAAKRPLVFTGFPVRALRSDAVGPSAEALTGSTDAVLSGDAG
RARVQFPPSYRAALIGATGLRLWMGFNTRDRNRTALERELRSLRALGVAGVHCVTGDHTQ
TGDRPDARPVFDLESTTTLPRAAGLGILTSFAESPAAPPLAERGARVAEKQRAGGRMCLT
QYAGDAEEVAAFVALCRRAGATAPVLPGVPLVVDREGARLLASFHAAKLPSGFIDRLFAA
RDVRAEGIRLAVEYGRALIETGVVGGVVIAGGARPGGEAAYAADLATVARALGGGS
>B5XZ25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae (strain 342)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A0S7ZTX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium SG8_11|TrEMBL
MESQKKFKPVFSIEFFPPKTEEGKAKLVEAREKLAKLHPAYFSVTFGAGGSTQQGTIDTV
KEIIDAGYSAAPHISCIGSTKAKIRQMLEDYQQIGVKRLVALRGDLPSGMGGVAGEFRYA
NELVEFIRNETGDHFHIEVAAYPEFHPQASSAEKDLENFKRKV
>A0A1E3G957|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piscirickettsia litoralis|TrEMBL
MHKSLALSFEFFPPGACQGRERLSSLCEEFSRFNPQYFSVTYGASGSDQQNTLLTVEQLT
AAGYGIVPHLSCMNLTEDKAITLLNTYRVLGVDQLLIVRGDLPIGEDCHSDFPYASDLIK
FVKNYYGNAFEVTVAAYPEFHPEAGNAFDDICYFRNKIINGASRAITQYFFDANAYYHFI
DICSKYKIDIPIIPGIMPINDYDKLLKISKLCQTEIPLWIHRRMQSYQDSESQRLFSIEI
VTKLCEDLIKFGAPGLHLYTLNQIDPVQEILNNLGLGERLKSSA
>A0A133Z4Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium kroppenstedtii|TrEMBL
MPPRDDAAERRLSDAAATFHDLGASFVSVTYGAGGSSRSRTIRIGQELAHTPLTTLVHLT
LVQHTVDELKEIIASYQECGLTNILALRGDPPGDPAGEWVSTPGGLEHAIDLIKLIQECD
TQRQFEIGIASFPDKHYRATDLDSDTAYTIAKLRAGASYSITQMFFDVEYYLRLRDRLAA
ADPVHGAKPVIPGLMPITSLKSLRRQRELAGCRVPADLEERLEKATATGDPSDPRVRQEI
RKIGIAHTTAMAERLISEGAPDLHFMTLNFARATQEVLHNLGMAPAWGTDHGHDAVR
>A0A5C6BLF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symmachiella macrocystis|TrEMBL
MRMRDIYSNGEFRLSIEIFPPKTEAGDAALFENLQRLVDYRPAFVSCTYGAGGSTRSRTI
DLCAEIQMRFALPATAHLTCVGATREELHQWLSEARQRGVKNIMALRGDAPAGAETFPHV
DGGLRYANELVELIRGELPDQGIGVAGYPEIHPEAPNADEDLSNLRRKVDAGADAVFTQL
FFANEHFFEFRRRYEQAGIKIPLIPGIMPITNFERIKRITKMCGAAFPETLATKLEAAQD
DEQAQFHIGVEYAVGQCRELMDNGVPGIHFYALNKSKACEAILNALDYQAVT
>A0A1Y3CYM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4169|TrEMBL
MSKRVPISFEFFPTKTDVGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFTIEVAAYPEMHPQAENFDKDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRIQKQGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVNLCERLLAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A7H9AM47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Costertonia aggregata|TrEMBL
MKVTDHIKEAKGKTLFSFEIIPPVKGRNIQELYNNIDPLMEFKPPFIDVTTSREEYIYID
RDGLLDKKLTRMRPGTVGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNI
MALRGDAMREEKYFEPTEGGHNYAIGLVKQVQNLNCGKYLHEVIETDDCADFCIGVAGYP
EKHLEAPSMSTDLKRLKEKVEAGADYVVTQMFFDNKKYFEFVEAARKMGINVPIIPGIKP
IAVKRHLNLLPQVFKIDLPEDLVEAVEQCKDNKAVRQVGVEWCIEQSKELLVAGVPVLHY
YSMGKSDNIKGIAQEVF
>A0A256HKX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halorubrum sp. Ea8|TrEMBL
MSAGTQAIKRSDGVGALLTDARFELMPFESFEDEIRHLPDDATIAVTTSPQLGIDTTVER
TEQAAALGYDVSPHIAARYVEDRDHLDEIAERLTDAGVTDIFVPGGDREEPAGEFESAHD
LLVALDELGHSFDEVGITGYPEGHDFLDAEALSDAMAKKSPYATYLVTQLCYDPDAVLEW
IDDIRDDGVDLPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVRQLVGSRG
VYKPDDLIDGLAPYADDDHYKIRGIHIYTFNQTPDTESWRTERLGR
>A0A410H914|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter muris|TrEMBL
MSPLPLAGSAPTRARFSFEVFPARSGAAALALGHAVQHLSAAGPDFISVTYGANGSNRDA
SLDLLKYLRDHTDALPLAHLTTVGESRDAVRETIHRIMDAGVHDFLALRGDPPRGLDEHD
PAVTGSLSSLELVDLVAEARAERPPLTSVGRTAVAAYPNGHPLSRSRSQDIEWLIEKQEA
GAQFAVTQLFFRAEEYLGFVGDAQSAGLRIPVLPGLMPVSTSAQLRKVASLAGRPAPEGL
ERALEEAGGYAPELGVEHTVDLARALLAGGAPSVHLYTFNRHEQVLAVLRELQLLTPDPI
G
>A0A454AA70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O6:K15:H31 (strain 536 / UPEC)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1D3UTC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella forsythia|TrEMBL
METVIDLIKNSQRTAFSFEILPPLKGNSIQSVYQVIDKLREFEPKYINITSHHSEVIQRV
EPDGSIRTVNLRKRPGSVAIASAIQNKYGITAVPHLVCKGFTKDETEYGLIDLNFLGVNN
LLLLRGDIKRLDLTKDPKRCHDHATDLQHQVNDFNRGIALDGSAIEDIETLFSYGMACYP
EIHEEAPSMESDIRYAKMKVENGAEYLVTQMFFDNDKYDSFVAQMRAEGVTVPIIPGIKP
IVFKDQLTVIPKIFHCTFPEPLTQALRQCKNDDEAKAVGIEWCIAQCRDLMKRGVPSIHF
YSFLASDSVRQVAKIIY
>A0A4D8R0H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum brasilense|TrEMBL
MTSGIPSVSFEFFPPKTEKMEQSLWQAIQRLAPLSPSFVSVTYGAGGSTRERTHNTVTRI
QKETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPETEGGVGGRYVPHPG
GYAYAADLVAGMKKVADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQFFFD
NDAYFRFLDRCAAAGITVPIVPGILPITNFARAVEFAGKCGAAMPQRFAETFEGLDADPE
TRQLVAATMAAEQCQALQAQGIKDFHFYTLNRSDLTVAICRMLGVKAKQPAVS
>A0A0C5WVX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Linhai str. 56609|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TAQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>Q66G75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pseudotuberculosis serotype I (strain IP32953)|TrEMBL
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIAIDYWNSGIRHIVALRGD
LPPNSGKPEMYACDLVGLLKDVGDFDISVAAYPEIHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFD
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A2M6ZAW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium CG07_land_8_20_14_0_80_52_14|TrEMBL
MKTEPISNLERVLSEGRFAVTAECGPPRGANAEVIRKKGALLKEVVDAVNVTDNQTAIVR
MSSISSCAHLLALGIEPVMQMVTRDRNRIALQSDILGAYSLGIQNILCLSGDHQRFGSQP
DSLNVFDIDSMNLVRTVYTMREEGTDMSGHLLDGSPRMYIGAAANPFADPFEYRVIRLAK
KIDAGADFIQTQCVYNLERFRQWMSMASGEGLTEKVHILAGVTPIKSAGMARYMAKNVAG
MDVPESIIRRMSQVPKEKAAEEGIAICLETVAALQEIPGVHGIHIMAIEWEEQVKIIVER
AGLLPRP
>A0A2K1FTA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum brasilense|TrEMBL
MTASLSAPPSISFEFIPSKTETMEQGLWQSIRRLAPLAPIFMSVTHGAGGSTRERTHATV
CRIQDETSLPAAAHVTCVGATRDEIDTIAHSYWNAGIRHLVALRGDPSDMPGGSGRCEPS
PGGYAYAADLVAGMRRIADFEISVAAYPESHPEAPSVQFDLDNLKRKVDAGATRAITQFF
FDNDVYFRFLDRCAAAGIHVPVVPGILPITNVARAVEFAAKCGASMPARLLETFEGLDDD
PETCRLVAATVAAEQCQALQAQGVRDFHFHTLNRSDITLAICHMLGIRAAVPAP
>A0A549T9A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylosinus sporium|TrEMBL
MSDNRSLWPPGHFDISYEFFPPKTPEMEAQLWDSIARLAPLKPKFVSVTYGAGGSTRERT
HNIVARLAAETDILPAAHLTCVSAARAEIDEIVRDYWNAGVRHIVALRGDPPTGVGTRFE
PHPEGYRSSTELVRGIRAIRDFEISVSTYPEGHPESRTIDDDLDALEAKIDAGATRAITQ
FFFENDVYFRFLDKARARGIAIPIVPGIMPVQNFKQTANFARKAGASVPDWLAHRFEGLD
DDPVTRRLIAAAVAAEQVLGLAENGVREFHFYTNNRADLVFAICHLLGVRPVTEKAAA
>A0A1I2HH62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella marensis|TrEMBL
MPAISFEFFPPKTDEQREQLDRTARLLKGRGPDYVSVTFGAGGSTLSYTGETVARLHREH
GLDVAPHLSCMGGTRAEIAELLDGYRAAGYRRLVALRGDLPSGMASPGDFRYAAELVSFI
RQHSGRHFHIEVAAYPETHPQADDALADLQHFKAKVDAGADGAITQYFYNADAYFRFLDD
VRRLGVEVPVVPGIMPIGNFSQLKRFSDACGAEIPRWIAKRMQAHGDDAEAIRELAADVV
AQLCQRLLDGGAPGLHFYTLNRAKATQAVLERLSI
>A0A3C1QSU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MSLASFYLSHRKALSFELFPPKTPAGDAALLANLRELSRFRPDFVTCTYGAGGSTRGKTL
DVCRMVKREFGLPVASHLTVVGSTVDELRAYLDEAIEAGIDHLVALRGDPPAGSGKFEPV
PGGLSYADQLVSLVREQGLPLGIAVAGYPEVHQEAPDAATDLRNLKRKVDAGADIVLTQL
FYDNDDYFRFVDACEREGITVPIVPGILPIVDLAQVQRITSLCRAKLPQRLLDRLGEHAT
PEWQQQVGIEHATEQVRDLLERDAPGIHFYVLNKSQATSKVLEAVDWHGS
>F9MM25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera sp. UPII 135-E|TrEMBL
MSVKNKTTFSLEVFPPKKEMPLASVYPTLTELSVLHPDFISVTCGAQGTGSNRTAEIAAT
IKEQFNLEPVAHLPGIYLTKEEVCNTLKELKKHRIHKILALRGDMTPEKEPAHDFAHASD
LIRFIKKESPDFHIIGACYPEGHVESKRPALDIIHLKEKVDAGASSLISQLFFDNTLFYR
FLERCEIASIHVPIAAGIMPVTNKKQIERMVSLCGATLPLHYQHLIAKYGDNPVAMRDAG
IAYAIAQIIDLLAHGVDGIHVYTMNNAYIAQKIADAIRTLL
>A0A848V1A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hellea sp|TrEMBL
MAEFCYSFEFFPPKTEKAGARLEAALDELETLNPAFVSITYGAGGTTRERTFKTVENILK
NRSVDPATHLTCVNASRAEIDEIVQGYLDMGITQFVALRGDPPGSVDGIYTPHPEGYAFG
SDLVAGIRSRSPNAKISVSAYPERHPESADWDAEIDNLKRKADAGANQAITQFFFRSEDF
LRLQERVADAGMDIPIIPGIMLQPNFDGLKRMAAMCGVDVPGHLARRFVQAQGDMDQCRD
ITVDYFSGLIQELQNGGVGDFHLYTLNTAPIAAEVVHNIRGQ
>L9MIC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. OIFC021|TrEMBL
MTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLL
TGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLH
KKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGI
VITPHMLKVLADEKQAGHTDRVYLRCALQILICGHLGFAGIHLSACHKPEEQMLLESYIE
QYRHLNLKALEELWSSLWQVKTGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKI
AKGVGRFIFKASFWENSVVAKALLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGL
ANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKQTEVLKEKLIPTIPLETRGTSSWKNWY
LGAEA
>A0A7L6ILU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. RHBSTW-00570|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIAQDYWHNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A2V7C9N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPYELSRRLEAAPLLCDGAMGTLLYARGVSLDACFDVLNVNNPRVVQSIHADYIAAGADC
IETNTFGANRFKLAVHGLDRRVREINRRGAAIARDVRESSGRDVFVLGSIGPLGKYLAPL
GTVTADDARAAFREQAEALLEGGVDAIVLETFSDLEEVTLAVAAIRSITDVPIVAQMAFT
NDGVTFTGRPAAEVARILRALPVQALGANCSVGSSTLYEVLEQMHAEAGNLPLSIQPNAG
LPSRIGERLIYLSSPAYMAEYAERMVASGARLVGGCCGTTPQHIAAMREVLDRRRPARPE
TRRAPVTVRPMAATASPGLHTARPPTVLGRKLAADEFVVTVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLPTALLVRDATGLDINMHFTCRDRNLMGIQGDLLGAH
ALDVRNILAMTGDPPRTGDYADATAVFDVDGVGLIEILRRMNEGRDATGSSIGEPTSFCV
GAALNPAAADVAREIDRFHRKVAAGARWVQTQPVYDLELLDRFLDRAGGSPVPVLVGILP
LHSARHAEFLHNEVPGISIPGAVRRRLHEAGDGALRVGIAMAQDLVRVVRGRYAGAYLMP
SFGRFEVVAEVLDAIH
>A0A3C1GKD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MGGGLRQALRHGGGHADRAEGARRVSNPLAVALRAGRFVHVVELVASRLRREAQVLDVAG
RLAGLPEVVAGSITSYAGGAIGHDPIRVGTAARARGLAPNIHLTCVSQDRQGLRKILEDL
HALGIENVFALSGDYPQGSDPGQPPPVFDLDSVQLVRMIADMRRAGMSFHISVAVXAVSP
FKYVEADCVYQYLKLEKKIAAGADLAITQVGWDARKFLELKRYLDQRGLRTPVLGNVYVL
GKRPAERMAGGQPPGCWVSPALLAAVREESAARDGGRRARLERAARTVAVLRGLGYAGAY
IGGTHDAEEVDGIVRRGLELAPRWEELAAELSYGAPDGFYLYAETSGSGRGAPAPSSTAS
TTITGLGGDRGPAARPASGSRAALPRVLDALGRLVPVDRDTLARRGLTSVFRWVDRRPGV
AHALERAELLVKRPLFGCQACGNCVLGDLEYVCPQTCPKQMRNGPCGGAALGRCEVLDRP
CIWVGVYERARATGRVDDLRGYIPPPDRSLQGTSSWINYFLERDSRPAR
>A0A1H7KCD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus albus|TrEMBL
MKTCELFKNKTTLSFEVFPPKSDTPIDSIYSTIDGLAPLKPDFISVTYGAGGNGSNATIG
ICEMIKEKYSIEPVAHLACINLTREKVLFELAQMKAAGIENILALRGDLNPNIPPHNDFK
YASELIELIKEQGDFNIIGACYPETHPEAASSVDDIKHLKEKVDAGCSQLISQLFFDNED
FYAFREKCAIAGIDVPIEAGIMPVTNPKTIARMATLCHARLPKKFLTIMDKYADDPISMR
DAGIAYAVSQIVDLIANGVDGIHLYTMNNPYIATKICEAVQSLFN
>A0A1E4WWF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. ANP5|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A240UPU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kushneria marisflavi|TrEMBL
MSDSRAPELSFEFFPPRTEAGRDRLPEVYTKLAELDPRFFSVTFGAGGTTRDFTFDAVKN
ISRDTGICTAPHLSCVASDKADLRRLLTQYREHGIKRIVALRGDMPSGMLGLGEFRYARD
LVDFIREETGDHFDLTVAAYPECHPQAQNFERDIDHFVDKVRAGADMAITQYFFNPDAYH
HFVDRVRARGVDVPILPGIMPITNYTKLARFSEMCGAEIPRWVRRQLESYGDDSDSIQAF
GHEVVTRLCQQLLDQGAPGLHFYTLNQAEACTRIVSDLSLEKAGR
>A0A2U3I1Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia novacaledonica|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRASRAELKTLSPKFVSVTFGAGGSTQQGTLDTVLEMAA
EGFEAAPHLSCIGSSKENLRAILTQYREHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQEHGDWFNIEVAAYPEFHPQSKSPRADLENFARKVKAGANSAITQYFFNADSYFRFIE
EARKLGVDVPIVPGIMPITNFSQLMRFSDMCGAEVPKWIARRLESFGDDRESIRAFGVEV
VTGLCRRLLDGGAPGLHFYTLNGAWASKTVCERLGFKSA
>A0A3Q8XHN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MSLLAQYFAQQQFCVLVEYLSSHQAQWPVNAQFAGFPAAMTLADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDAKTQGQKNLLLLTGDKLKQHCYSHDLEPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFIKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMAA
LQDVHAFLARHQYAQKMLACVMPLTLARAKFMLKHKVAGIVITPHMLQVLQQEKEQGLSD
RVYVRCALQILMCRHLGFAGVHLSACHQPEEQSLLERYIEEYRHLSFAECERLWNTLWQV
QTGTEFHPKLAYYSRPATSSQIIKYQHLHLMHDALFESRLAKGVGRFIFNFNVWDRTKAN
KALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDREC
IHSVKARLAKAVGQTKILKEKLIPTVSIAVRGTSSWKNWYVEAAG
>A0A2T6ZSV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tuber borchii|TrEMBL
MGSRRSLSNTLFQRQLRGVQNLYDRMDRMNQLGPQFIDITWNAGGRLSNLTCEMVNVAQS
VYGIETCMHLTCTGMPRSKVDNALKEAYKAGCTNILALRGDPPRENEKWEVDPHGFRYAK
DLVKYIKANYGDHFDIHVAGYPEGCEDGTDPELLLEHLKEKVDAGASSIITQMFYDVDIF
LDWVKKCRDIGITVPIIPGIMPIHTYAAFMRRATWTKCHIPEKWLSLLEPVKNDDVAVRD
IGRDLMVELCQKIIDAGILHLHFYTMNLATATRMCLEGLGLIPSLEERTKALPFRPSLGL
NRKEENVRPIFWKNC
>A0A735M9L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 47:b:1,5|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8F6HK62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paeniglutamicibacter sp. Y32M11|TrEMBL
MSIATSVAPPSLSYELYPPASRDASESVFSTIAALESTDPDYVSVTYSGSPTRRAASLEL
IDHLIRDTRLRPLAHLTCVGESRESLQNLVRHFISLGVRGVLALRGDLPTKSDEWRGEFP
FARYLIELIREVEAEHSAALAGGRLGVGVAAYPIRHPESPSFDHDIEVLLAKERSGANYA
ITQVYFQASEYTNLVESAQRAGVTIPIIPGVIPLNSLKRLNRLASMTGVCPDPELAHALE
TADSEAERHRIGVAAAVNLARRAFDDGAPGVHLYTFNDHRGSLDVVEQLELPRTRAKVTR
TWATRAVA
>A0A4S8HNY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niastella caeni|TrEMBL
MKVIDHIRQAKDSLISFEILPPLKGKTINSIYEHLDPLMEFKPAFINVTYHRSEHVFKKK
ADGTFEKVEVRKRPGTVGICAALMNHYRVDAVPHLICGGFNKRETEDALIDLHFIGVDNV
LVLRGDAAKNETVFEPEPGGNSYALDLMKQVVNLNNGVYLEEDIRDGFRTNFCIGVAGYP
EKHFEAPNLQTDLAFLKAKVAAGADYVVTQMFFDNQKYFDFVKRCRENGITIPIIPGLKP
ITSKKQLSVIPRTFHVDIPDDLSNEIINCKTDADVEKVGTEWLLLQSKELKKAGVPVLHY
YTLGKPKVIYNAVKQLL
>A0A701XPZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 47:b:1,5|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATGDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDIYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A544U9J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. SDF0037|TrEMBL
MGLLERLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQKPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLETRVQQYNEAAITIAKRAADGGQFVLGTIGGIRGIRKSDATLEEIL
ATIDEQATVLLAGNPDGLLLETYYDFEELTATLSMLRAKTKLPIIAQVSMHEPGILQNGM
SLNNALHELEALGADIVGVNCRLGPHHTIQAFEGAELPKQAFMSAYPNASLLDLEDGRVV
YESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVEEKYTKPEKIEIV
REAEPANYEPLHEKVKRERSVIVELDTPRHLEIEGFIKGAKKIYEAGADVVMMADNSLAS
PRISNVAMGALLKETHGIRPLTHITCRDRNLIGLQSHLMGLNALGIHDVLAVTGDPTKVG
DFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVSRL
EKKIEHGADYFISQPVYTKEKIVEIHEATKHLETPIYIGIMPVTSYKSAEFLHHEVPGIK
LSDDALARMKACGDDKERATLEGIAIAKELVEVAAEYFNGIYLITPFLRYDMTLELMKVI
EQLDEQKKGVSING
>A0A4R4SD40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. GC306|TrEMBL
MRRLRQDRPPTVQELLASGDRSFSFEFFPPKTDKGALNLWRTIRELESLQPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVNHSQAELRHLIGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPDGVEYASDLVRMIRSYGDFCVGVAAFPYKHPRSPDIESDTRYFIEKCRA
GADYAITQMFFRAEDYFRLRDRVEAAGCDVPILPGIMPVTQLSTIERSEQLSGAPFPPEV
RARFEAVADDPEAVRRLGVEHAAEVCRELLEQDAPGIHFITFNKSTATREVYGLLDAASY
GGRGSAPPMTA
>A0A2U1DBI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Convivina intestini|TrEMBL
MSNHLKNNLYQNQLIFSMEVTVADLKRQDTVKKINQLTNLQYLSLVNHTKNDQEWQELLT
AGQALQMRTQRPLLLHLPAGTIAESQIQQKLIALQENQLDHLLIMRGDRVAPAANYHSAT
SLLKDINKSAFNFDLGATVDPNKIATLGLPALLSEIDTKIAAGAEFLITQIFFDLGLFKQ
LQEALQQRYPQIPLIAGVFPVMTVKQGQWIENNLGQGLPVTLTRRLMTLPADPQLKQYWC
GWLKELLLTGPAGVHFFAGIDIDFIKELMDIAY
>A0A2U1D9J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Convivina intestini|TrEMBL
MNLKDVFQTKTVFSLEVFPPKSELATQKLLNSLTGIQSIKPDFISITLGAAQMDIQKTVN
LATAIQEQLSIPAMAHLTGLYLSKQQAADTLSILKESQINNILALRGDQVSNCPPVGDFK
YAAELVNFIKCHGDFDIAGACYPQKHPESSDFVADTLHLKEKVNQGASHLITQMIFDNEA
FWQFKERLQLANINVPVEVGIMPCTNHQQIQRITALSGIQMPKKFTNIMARYADNKEAMR
DAGIAYAIDQIVDLVASGVDGIHLYTMNNPENAQRIWEATHTLFEAQNKQLAYPL
>G3AQG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1)|TrEMBL
MKISQKLQQAHAGPNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALDKAFKSGCQNILALRGDPPLD
GSESTGDFKYAKDLIKYIRKKYGDHFNIGVAGYPEGHPEEESEIKTLHYLKEKCDVGADF
IVTQMFYDVDNFIDWCKKIRKIGVEIPIIPGIMPISTYAAFVRRAKWSEIAIPQHFLDVL
DPIKDDDYLVRERGTELVSDMCIKLLHSGYVNHLHFYTMNLEKATVMILEKLNLIEAVKS
HDVVGSTELPWRKSLHPGRSKESIRPIFWQNRKYSYVTRTATWDEFPNGRWGDSRSPAFG
DIDLCATELLRQSPKRALELWGTPQSLKDMSDIVVSYLQGDLKALPWSDGPVGDDTKIIV
DDLIHLNKKGFFTMNSQPSLNAIKSSEKVFGWGPKNGYVYQKQYLEFFCHKDVIAKLLYK
IDSFNTKEGDTSSSVISYYAVDKDGHLTTNCKDDDINAVTWGVFPGEEILQPTIVEKTSF
LAWKDEVYRLFSEWGNVLGSNLAGADPEKIKGFLDLMNTLSNDFVLCNLVNNDFIDDNST
IFKLIEELDVKDLA
>A0A1H6M7G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fuscovaginae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASHNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKIPSAPHLSCVGDSKDDLRDLLTQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDIQHFVRKANAGADSAITQYFFNADSYFY
FVDRVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQAFG
EQVVTEMSERLLQGGAPGLHFYTLNLAEPSLAVWNNLKLPR
>A0A193LC29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia oceani|TrEMBL
MKTFKKAVREKDFAVTAQLFLRPETDAPAIQLQADVLKDAVDGILLTDNQYGQLHMSTTA
AASILLDYGVDPIIQLSSRNRNRIALMSDLLGAAAMGVSSLLLVAGERAPDSFQPKPKPV
MDLTATELIRTAATMNADEDLAHKPDFYIGGIVTPVMPKPNWAARNLRGKIEAGAQFVQT
HICMDVDLLSRYLGFLVSNKLIQQTSVIGAVAVLGSVEDAIWMRSNRPNTMLPDSIVTRL
QAASDPREEGIRICAETIKAMRAIPGIAGVNIMAARDLTTIPAVIDAAEIHG
>A0A5S4UP71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinomonas sp. IMCC 4694|TrEMBL
MKSELATKFQDPSRGVYFIGTTPPKSSLEEEQLEQISEKLLDRLSNIDVDGLIVYDIQDE
TSRIDKPRPFPFMETHDPRAWSKRLHEASGKPVITYKSVSSRSSEAFSGWLSQAWEEYGI
RDLVLVGSPSSNGDIKLPLPEAYKTLKACPHDFNLGGVTIAERHAKKGDEHERLTKKSAA
GCEFFISQAVYNHQATADLISRYARACKEQGTAPKRIILTFTPCGSAKTLEFMEWLGISV
PDATKHRILDAKAPLKESIKICRNALEQIIETALPLGVPLGLNIESLTNRKEEIDASIRL
YKLLKATLDLKLAEHALISNA
>A0A1G1HIG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium RBG_13_43_8|TrEMBL
MKGGSNLEKVLEGGYFAVTAEVGPPKGTSASVVQKKGDLLKSYCDALNVTDNQTAIVRMS
SLSGCVLLKEMGLDPVMQMVVRDRNRIALQSDILGAIALGIRNVLCLSGDSQKFGNHPTA
KGVYDIDSIQLVQTLKTMRDEKKFLCGEAISGEVPLFIGAVENPFADPFEYRVTRLAKKI
KAGADFIQTQSVFDVDKFARWMKMIRDQGLDKQVHILPGVIPIKSVGMARYMRDNVSGVS
VPDEIVSRLEDAKNVKEEGVNITLEIIEQLKEIDGIHGIHIMAVAWEDIVPNIVERAGLL
PRPIL
>A0A193LC79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia oceani|TrEMBL
MKTFKAAAEDRDFAVSAEIFLKPDTGAEVIREQASLLKPAVNGVLLTDNQFGHPHLSTLA
AASLLLANGVDPIVQLSTRNRNRIALLSELLGAGALGVSSLVLVRGDRVPDGFKPRPKAV
HDLDAAELIATASKLTLDERMSALPEFYIGGLITPHAPKPGWKAAKLIEKIEAGAQFAIT
HVCMDIPLLQIYMKHLLAIGLLNRVRVCVSLAIIESASDADWLRAHRPNVNVPESQLARL
RQAADPYQESVRICAEQLSALREIPGISGAHIVATRQLAAIPAAIEAAGLLPGR
>A0A2T5QMG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter oleivorans|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIDKVLHFSGK
ARDIQDFEHFLEQAQATNIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHHYSQ
QILACVMPLTLARANFMVKHKVAGIVITPHMLKVLADEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVTSGKEFSPEIARFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENSLVAKVLIKTEVLSKHSLV
GCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKALEQT
EILKEKLIPTVPIETRGTSSWKNWYLATEA
>B7HCM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus (strain B4264)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>M1PQL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar thuringiensis str. IS5056|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1I8BDP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meloidogyne hapla|TrEMBL
MNIIKYNSLANKLNLINSTDGPFFCIEVSPPKEINEIKYFISSINKLINKTTNNSFLFLS
IVAHAENKPTDISLPNSSTSTASKIINENILPKNSHLLLHITGKCFINVPHNYVDIYFTK
LKQLGINNYFVLSGDSPQRINYNYENYNLVENSLLSSQLNSLHLIKRIRKSNKSTSFKNK
LTFAVAGYPECHPFAFDRNSDILFLKRKIYEGNANFVICQFSFDKAVEKFFQFVADCREA
GINVHIIPGILLFQVINQPYLFF
>B6IP21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillum centenum (strain ATCC 51521 / SW)|TrEMBL
MSLADLVDAVAPPKPLLESPSGLRVSFEFFPPKTEKMQESLWQSIHRLAPLGPAFVSVTY
GAGGSTRERTHATVTAIQAETGIPAAAHLTCVAATQEEIDAVARAYWDAGIRHIVALRGD
PPPRPDGTGGLGGTGYQPHPGGYAYAADLVAGLKRVADFEISVACFPEVHPEARSAEDDL
DNLRRKVDAGACRAISQFFFDPDAFLRFRDKAAARGIDIPLVPGVMPIMNFAKAVEMGGK
CNCAVPAWMTDLFDGLDETPETRQLVAATVAVEQCRYLEREGVKQFHFYTLNRAELTVAI
CHMLGVRAKRPPTA
>A0A258DHM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichales bacterium 32-46-8|TrEMBL
MKLSAEFFPPRTTEGLDKLVEVAEGFRPFNLDYLSVTYGAGGSTQERTLATVKALRARGW
DVAPHLTCVDSERGKIADLLKIYMDLGVHRIVALRGDIPSGMRDLGDFNFAIDLVKFIRD
TTGDHFHIEVAAYPEVHPQAKNWQTDLQHFADKMAAGANA
>A0A1J9QDW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emergomyces pasteurianus Ep9510|TrEMBL
MEKISNKIAALPRDANYFSLEFFPPKTQMGSSNLQSRLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDDALSEAKVLGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTHAVDLVKYIRHTHGDYFCIGVAAYPEGHSDESYPEVQDPARDLPYL
VEKTKAGADFIMTQLTYDLEAYKRFEEMLRNHESGVFRTIPIITGLMPIQSYHILTRTTK
LSHARVPPDIMARVEEVKSDDEAVKRIGVDILCEIVNGIKNIPSPGPRGLHFYTLNLEKA
VAFTVEKCNLIPASSEPSSDSDTDLDSAVFTAQGKQNGVSLISRRRASSLNSQPHNRLIV
DRPSDAGTSSQTSTTHETQALGAGMPALNPPHRTTALQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLKVNATVARRLWGYPVTKEDINNIFQRHVSGELHIVPWSEGGA
QDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGLRNDHPIFGWGPRGEGFVFQKAF
VEFFCPAHDFKTILKPLFESHGPDELAWFATNAAGDFQSFSHPSDATMDNYSGAVDVFLD
SNATSSNTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIFPRGSPTEK
LLNQLKNDVWLVCVVGQKYGAGCGSQEAAEAEGKLLWRLLGGKDMEVTSANAH
>A0A355XT70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp|TrEMBL
MSVIDLLKDNTASQRFSFEVLPPLKGNGTEALFRNIDKLKDFDPLYINITTHHSEYVYRE
LPDGQFERLRIRRRPGTIAIAAAIQQRYGLPVIPHIICSGATAEDIEYELIDLQFLGINN
VLLLRGDKAKEDRMYKATPGGHEHTTDLIRQVNAFNAGHFADGSDIRHPGQPFHYGVAAY
PEKHEEAPNLEMDMKHLKEKQDLGAEYAVTQLFFDNEKYFSFVEKAHQMGITIPIVPGIK
PFAKLSQITQVPKTFHCDMPQELAKEAVKCKTDDDAKALGVEWTTAQCKELYARGVKDIH
FYTISAIDSVAQIAKNLL
>A0A1X0BA68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium aquaticum|TrEMBL
MLNIDQVDPLSRLLQNARLEILPLSGIRETVLASIPEGSTLTITCSPKHGVQRTVETAEF
FAAHGYEVIPHLAASQIQDQSHLSQIVARLSASGIDEVFAIGGDGQRAGDSTYSSAADLI
EDMLELPGHPSRIGIAGYPEGHPEISSDDLAHALRRKARYASYIVPQMCFDPSIMRTWIE
SVATTYPALPMVLSAPGAVARRKLMEMSPRIGVGNSVRYLSKNKRTMAKLLLHKMFTPDE
LLEDVLEDTATATRIVGIHLFSFNQIQETEQWRRQTVQRLTATRSQA
>A0A3L9YEC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. 100|TrEMBL
MNAAHAQGTGFPVSFEFFPPKTPEGADKLRVARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILSEGVGAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLQAYVTKVRAGADSAITQYFYNSD
AYFRFVEDAHQLGADVPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A554AJ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ef1|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETADHFHIEVAAYPEMHPQARNYEDDLANFVRKAKAGADSAITQYFFNADSYFY
FVDRLQALGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTRSIQSFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A4V6QLS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira koniambonensis|TrEMBL
MKKILEIYKTAKTPVYSFEFFPPKTPEGETKLFEAVEELSKVAPGYITVTYGAGGSTRDK
TIRITSELAKKFSLPAAAHFTCVGGNKDEIRVILKQIRESGIENLMALRGDPPKGEEAFK
KVEGGFGYASELISFIKQEGFDFCMGAACYPEKHPEAASLESDVDNLKRKVDSGASYLVS
QLFFKNSNFESFLNLIRQKGINVPVIPGIMPITSFTQIERFKAMAACEFPEKLVSDLEEV
KDQPEEFYKRSVNFSVNQCRELVKMGAPGIHLYTLNQSPASLDIVRELKN
>M1BBU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solanum tuberosum|TrEMBL
MKVIEKIQEAAKTDKVIFSFEFFPPKTDDGVENLFERMERMVAHSPSFCDITWGAGGSTA
DLTLDIVNRMQNMVCVESMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGIATKEIYENDLAYLK
KKVDAGADVIVTQLFYDTDVFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTK
IPEEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALAILMNL
GLIEESKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTTGWDEYPHGRWSNAQNP
SYGALTDYQFMRARSRDKKLQEEWAVALNSVEDIYEKFKDYCLGKLRSCPWSELDGLQPE
TKIINEKLGQVNTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLELFCSQEKLN
ALVEKCKSFPYLTYMAVNKEGNWISNVNQTDVNAVTWGVFPAKEIIQPTVVDPASFMVWK
DEAFEIWSRGWAQLYPETDPSRKLLEQVQNSYFLVSLVDNDYINGDLFSIFKDI
>A0A2K9AXM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kangiella profundi|TrEMBL
MNRAERLYSHVQELERINNDFASLSGNVNISFEFFPPRSEDMNQVLWQSIKKLEPLQPDF
VSVTYGAGASTRERTHDVIEKIYTETSLNAVPHLTCIDASEAEIEQVTHRYWEIGVRHIV
ALRGDKPDDSDKHNGDFTYATDLIKKLKSLYDFDISVAAYPEVHPEAESAQSDFENLKRK
VDAGANRAITQFFFNAEHFLRLRDKCVRDNVEVELIPGILPVTNFLQLLKFARFTQVEIP
GWMHKLYQGLDQDPITRQLIASHIAIEQVKLLAKEGIKNFHFYTLNRADLTYAICHSLGR
RDCFAAAS
>A0A1A7P5Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallibacterium anatis|TrEMBL
MSYAKEIDVLNRSIADLNGDINVSFEFFPPKNEKMETLLWDSIQRLKSLQPKFVSVTYGA
NSGERERTHSVVKAIKQQTGIEAAPHLTGIDASPEQLKAIAKDYWDSGIRNIVALRGDEP
PGYDKKTFYAKDLVKLLKEVADFDISVAAYPEVHPEAKSAQADLIFLKQKVEAGASRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFVQLQKMAKVTNVKIPSWMFKLYDGL
EKDQTTRNLIGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGVRPSLAA
>A0A4Q5R3B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagaceae bacterium|TrEMBL
MKVTEHLSRADGRTLFSFEVLPPRKGENIRTLFSNIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRKRPGTVGICAAIKNRFDVDTVPHLICGGFAKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFQPHPDGHRYACDLIGQVAELNHGRYHDHDEQYQPAGAEPVLCTDF
CIGTAGYPEKHFEAPNLGSDIRFLKEKVDRGADYIVTQMFFDNEEFFKFEKHCRDAGITV
PIIPGLKPLTTKNQLTALPRAFFLNLPEALTEAIHAAKDNAAAREVGIEWCLNQSRELMA
HGVPCLHYYSMGKSEAIRRVAAGLF
>A0A231HJL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp. T2|TrEMBL
MNASKALSLEFFPPRDAAAQEKLSVAARRLSALNPAYVSVTFGAGGSTREGTAEAVRLMQ
GLGFDAAPHLSCVGSTRSVLADILDAYRNTGVRRVVALRGDPPSGMGIDSGDLHYAVDLV
RFIREHSGDWFHIEVAAYPEVHPQAKSAQSDLDHFVSKVNAGANAAITQYFFNADAYFDF
VDRAQAKGVNVPIVPGIMPITNQVQLLRFSDMCGAEVPRWIRQRLADYQGDLASIKAFGK
DVITQMCQRLLDGGAPGLHFYTLNTAESTLAIANDLKLG
>A0A4D7IY40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia heimbachae|TrEMBL
MSFFHVNQREALNQSLAELDGQINVSFEFFPPRSEEMEQTLWKSIDRLKNLKPNFVSVTY
GANSGERNRTHSIIKDIKDKTGLIAAPHLTCIDASRDELKEIARDYWNNGIRHIVALRGD
LPDNSRKPDMYATDLVELLKAEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLDRFAKMTNVRIPSWMRKMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A0A8L9P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyveromyces dobzhanskii CBS 2104|TrEMBL
MRISQKLQRAHEEREDATFSFEFFVPKTSQGVQNLYERMDRMYQTQPEFIDITWNAGGRL
SMLSTDLVATSQGVLGLETCMHLTCTNMPVSHVDDALKKAYDAGCQNILALRGDPPINSM
GEEEEWKPCENGFRYAKDLVAYIREQYGDHFDIGVAAYPEGHPECDCEEKLLHHLKEKVD
CGADFMVTQMFYDVDKFIDWCAAVRKIGISIPIIPGIMPITSYPAFIRRTQWCQINVPEN
FVKLLEPVKDDDQLVREVGTNLMVELCQKLLDSGYVNHLHLYTMNLEKASLMILERLGLL
KSGIVGKDAVEPLEPLPWRKSLNPKRRNELVRPIFWQKRPYSYVARTSLWDEDEFPNGRF
GDSSSPAYGDLDLCGHSLIRQSVKKSIELWSKPSTLDDISNLVISYLEGKLKCLPWCDVP
LNHEVDDILLNLIDLNRHNIFTINSQPKVNGKPSTDPVVGWGPSKGYVYQKEYLEFLLPK
EKLAKFQEICEEHSDHLTYFAIDAKDNLTTNHPEDSRANAVTWGVFPGSEILQPTIVEKV
SFLAWKEEFYTILQEWKLNFAEHKASDSESLVNSIIDNYMLVNVVDNDFISSNDTIFKLL
QRLY
>A0A6F8YYQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytohabitans suffuscus|TrEMBL
MSGLRAALDERRFVVTAEVAPPRDADPEAIGRKAAGLRGWVDAANVTDNQGANVRMSSLA
GSVLLRQAGIDPVMQLTCRDRNRIALQSDLVGAAAVGIRNVLLLTGDHPTLGDHPDAKPV
FDLDGVQLVWTARTLRDDGTLLSGRPLATRPSWLIGTVENPFAPPAALRARRLAKKVAAG
AEFVQTQYVFDVDAFARWVGMLRDGGVTERCAVIAGVGPIRSRRMLSFLTGSVPGVHVPE
GLRRRLAGVPERRVEEEGMRVCVETIQALAAIDGVRGVHLMVFGHEDEVPDIVRRAGVRP
FAELEGRR
>A0A7W5MYK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. BK369|TrEMBL
MAYAQIHPNWDKEPAGITDGYSLEMTAKDIASLREAAPLIPPETPVAVTYLPGEEAQARI
AATVAVRELGFEPMPHFSARRIIDVPEFEAYLQAVVEQAGVRRCFIVAGDPAEPQGPFFD
SSALIATGAFERAGITAIGIGGHPDGHPNMTEAECWAVLDKKVAEITARGMAPLIVTQFG
FDADSFLVWLEKLRARGIDAPVRIGVPGPAGIKRLLGFAARCGVGASASVMKKYGISLGN
LLGSAGPDKLVDAFASGLGPQHGRVRLHFYPFGGLAKTVEWIEDYRRRHPA
>A0A2D0LBK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus kozodoii|TrEMBL
MSFFHANQREALNQNLAELEGQFRVSFEFFPPRTAEMEQTLWKSIDRLSKLKPNFVSVTY
GANSGERNRTHSIIKGIKDKTGLEAAPHLTCIDASREELRTIAQDYWQNGIRHIVALRGD
LPINGGKPELYGADLVELLKKEADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFASATNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPS
>A0A1J4N222|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides luteus|TrEMBL
MSRRSAAATVRRLLLETRYEVLPTASIEEVVTTALPAGRTVTVTASPAKGLERTVDLAVR
LAGHGYDVVPHLAARMVSSRAELAEITGRLTAAGVTKVFVPAGDAEQPGEFPGALELLEA
LVDLGDPFSHVGVAGYPEDHPTIIHDRLVQAMWDKRRHATEIVSNLTFDPAALTDWVRRV
RARGVTTPIIVGLPGPVERAKLLAMATRIGVGESTRFLAKNKGMFARIAAPGGYSPERFL
MRAAPGLEGAEAVVTGLHLFTFNQVAETESWRRDLLARLGGDPL
>A0A0Q4J3G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf25|TrEMBL
MTPTISDMEEARRALDAPLFADLAGDCSVSFEFFPPKNEKMEAALWETVRALEPLAPKFV
SVTYGAGGSTRERTHATVERIARETSMPAAAHLTCVEASRAEIDEVAQAYWAAGVRHIVA
LRGDPPTMGQKFVAHPDGYENAAALVTGLQKLHPFEISVAAYPECHPDSEHQAADLDNLK
RKIDAGAMRAITQFFFTPEAFFRFRDAAAAAGINADLVPGILPVSNVGQVRKFAGMCGAA
IPPWMDRLFEGLDDHPGARALVAATVAAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLM
GLRPKAAAIAAAA
>X6JRX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L103C131B0|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDTIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMIADRLESILHDDITETQVDMVK
TAH
>A0A109BEU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sulfonivorans|TrEMBL
MAMTSERKSRLLGAGEIDVSFEFFPPKSEKMESALWSCIQRLAPLEPEFVSVTYGAGGTT
RERTHNTVVRLVDETDMKPAAHLTCVAATKDEVDAIARDYWERGVRHIVALRGDPISGPG
SVYEPHPGGYINAADLVAGLKRIAPFEVSVAGYPEKHPESLSVGADIDNLKAKVDAGADR
IITQFGFDNAHYLRFLERARAAGIWIPIIPGIVPIHNFKQVAGFAARAGASMPSWLARRF
DGLEEDPATGHLVAAAVATEQVMDLVDEGVKKFHFYTLNRADLVYAICHLLGLRPHAGSA
PAKIRAAS
>I4EY16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter marinus|TrEMBL
MRTAPAGESRLAAQEEGQPMKRSLTARDPATRASLRQVFQELGFEVIPFKKTEEQVLQHV
PKDVRLTVTASPAKGQDATVDLTVKLVGHGYSVAPHLSAQQVRDRAHLADVVARCREAGV
TDVFVVGGDPSDTPTEFKDALALLTALHELDHGFADIGIGGHPEGHPSVSPEVLFQALKD
KAAMATHIKTQIVFDPKLILDWARELKNRGIDLPVHVGVPGAVHRQKLLRVSGGLGVGES
AKFLKKQQNLLWRFFIPGGYSPDKIIKGLAPHIGKPDNHIEGFHVFTFNDLGPTEAWREQ
TLRSLA
>A0A2S6XZH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis pv. begoniae|TrEMBL
MISTDTPHLASTVTDAYSLEVSVKDIGALTNAAPRIVPGCAMFIPYLPGQNEAARLAAAQ
TVRGLGFEPVPHLSARRIGALEELQASVARLVDEAGVTRCLVIAGDPATAKGPFPDSVSL
IETGVFERAGIRCVGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
LVVTWLEALRARGMSHPVRVGVPGPASVAVLARYAARCGVGACASVLSNHGISIGKLFGN
AGPDRFVDRLVSRLTQAHGDVRLHLFPFGGIAQSVEWVAQYRSRNASQRLVGSEPADQA
>A0A3R7WEP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosalsum natronophilum|TrEMBL
MQGSFVDKIRSRNFVITAEITPPKGSNPFNAIEDAALIRNLVDAINITDNNRGVMRMSPI
SLGKVLQQQGYEPIIQMTCRDRNRLALQSDLLGAAALGLKNFCIMTGDHVSCGDHLG
>A0A0T6AQJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium CSP1-3|TrEMBL
MPGAAPESFQARLDRGPLLADGAMGTMLYARGVPFDQCFDALNVDRPDLVTAIHGEYIAA
GAELIETNTFGANRFKLSLHGLEDRVRATNVAGAAAARAAREASGRWVWIAGSIGPIGRP
LAPLGTVKAGEARQAFAAQAKALAEGGVDLLIFETFSDLHELTEGVAAAKEVTGLPIIAQ
MTFTHEGKTLLGHTPAEIVARLEELGVAVIGANCSVGSQGVLEVMEQMVLVSRTPLSAMP
NAGFPAYVSGRIIYFSAPQYMADYARQMVELGVTVVGGCCGTTPEHIQAMREVLRTVESP
PPPRLRPRVTVPAPPPVARPSPPTALAARLGRRFVLTVEVLPPRGTQEGPELEACQLLRQ
AGADTINVPDNPMARLRMSPWAMCLRIQTDVRMETVLHFTTRDRNLVRMQSDLLALHALG
IRNILVLRGDPPQLGDYPSATAVSDVKPSGLIRLIKQFNEGHDLAGNDLGQATTFLVGAA
LNMGARDLDRELRVLEQKLRAGVDFLCTMPIFEPATLDRVLDRIGPLPVPLLVGILPLHG
LRHAEFLHNEVPGMVIPSALRDAFRAAPRNGREVGLRFAEALVAAIRPRVQGLYLIPSFG
RYDRVLHLVQTLRKETPAPTDP
>B8LAU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. SKA14|TrEMBL
MMSARAPARAEAFINRYSLEVSAKALPALHAEADRIAPGTIISIPYLASEDDNARLAAAR
IVRQLGFEPMPHLSARRIGSRDALERFMQRAASEAGVQRCLLIAGDLAAPAGPFADSAAI
IDTGILERSGIKVVAIGGHPEGHPVMDSGECWQVLERKCQVIEARRMTPLIITQFAFDAD
IVLAWLDDLRSRGIRVPVLVGVPGPASITRLARYAAMCGVGASASMLARYGISIGRLLGT
AGPEVFVDRLVQGLTDAHGAVSPHFFPFGGIAASLTWIERYRRHALASSHS
>A0A5E5AM46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea sputorum|TrEMBL
MNGSDDNKTIMTQPSFSFEFFPPKTADGAEKLRATRAQLFPLGPKFVSVTFGAGGSTQQG
TLDTVIEIQREGVDAAPHLSCVGSTRDNIRDILTTYRDHGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGDWFHIEVAAYPEYHPQAKSPRHDLEHFANKVKAGANAAITQYFF
NADAYFRFVDEVARLGVDVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
EAIRAFGLDVVSALCERLLKEGAPGLHFYTLNAAAATKAMWQRLGL
>A0A5C4SPK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tamlana fucoidanivorans|TrEMBL
MKVTDHIKQANGKTLFSFEVIPPKKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYID
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VMALRGDSMKDEPYFRPVKGGHAYASGLVEQISNLNKGQYLHDDVEVEHNSDFCVGVAGY
PEKHMEAPSLVTDMRRLKEKVDAGADYVVTQMFFDNQKYFEFVEKAREMGITIPIIPGIK
PIAVKRHLQLLPQVFKIDLPQDLIDAVEACKDNKQVRQVGVEFAIQQSKELREAGVPVLH
YYSMGKSDNVHAIAKALF
>A0A396K5S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM22-11AC|TrEMBL
MKIKDILAEGRPTLSFEVFPPKTADAYESVEKAASKIAQLKPDFMSVTYGAGGGTSDYTV
KIASTIKEEYGVTPLAHLTCVSSTREKVHHVLEELKAHKIENVLALRGDIPQDGKTPEVY
HYASELIREIKEAGDFCIGAACYPEGHPESSNKSVDMDYLKQKVDAGCDFVTTQMFFDNS
LLYSYLYRIREKGITIPVIAGIMPVTSGSQLKRIAQMSGSYMPARFLSLVDKYGDNPAAM
KQAGIAYATDQIIDLLANGIKGIHVYTMNKPDVAAQIQSNISELLK
>C1A0Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus erythropolis (strain PR4 / NBRC 100887)|TrEMBL
MTFDPVRGRSSEGWATRTPSIVDRIASSTGSRIPFSVEFSPPRDADAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSTEELRAMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPEGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
YDTKYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVSAYDAEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGPEENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTPDTSVGTAQAV
>A0A5C4N1X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubellimicrobium rubrum|TrEMBL
MSRPAVSFEFFPPKNLEGSFRLWDCCNVLGPLGPEFVSVTYGAGGTTRTLTHDAVATIHK
HYGLTVAAHLTCVDATREETLAIADSYADVGVTEIVALRGDPPKGSDGFQAHPQGFASSV
ELVEALARTGKFKIRVGAYPEKHPDAADAKADIEFLKRKLDAGASSAITQFFFQPETFFR
FRDACVKAGITALIIPGILPVENWSGVKRLSARCGTDIPATTAHAFENADRDGTTELLAV
ATATSLCDRLVQGGAEHLHFYTLNKPSLSRDVCLALGITPKTRLQAVA
>A0A0M8X3K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL B-1140|TrEMBL
MALGTASIRSDHARTVRDMLAAGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSCDWDTDVRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLERIGSLTNAAF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSPQA
>A0A015TQ22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis str. 3986 N(B)19|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMTAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A0Q6FG50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantimonas sp. Leaf443|TrEMBL
MSTTAEKPDIAVSFEFFPPKSERMEENLWRSIERLAPLSPSFVSVTYGAGGSTRERTHHT
VKRILEETALVPAAHLTCVDATREDVAEVAEAYWNTGVRHLVALRGDSQAGVGGAYVAHE
GGYRNAVELVAGLKALRDFEISVSAYPEKHPESSDFATDIDLLKRKVDNGATRAITQFFF
DNDVYERFVERVRRAGIYVPIVPGIVPIHDFTKVARFSKATGASIPDWLAKRFEGLEEDE
QTRAHVAAAVCAEQVLDLKARGISDFHFYTMNRADLVYSICHILGLRAARSDTRSAAAA
>A0A250B1J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibbsiella quercinecans|TrEMBL
MSFFHANQREALNQSLAELHGQINVSFEFFPPRTTEMEDTLWQSIDRLSSLKPKFLSVTY
GANSGERDRTHSVIKGIKERTGLDAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPAGGGKPDMYAADLVTLLREVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDNDPETRKMVGANIAMDMVRILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A0Q7BXR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelomonas sp. Root405|TrEMBL
MTTPVSFEFFPPNTPVGVEKLKTVVQELGALAPQYFSVTYGAGGSTRDKTLGAVMDIAAA
GFEAAPHLSCVGSTRENIAEILATYRAQDIHRVVALRGDLPSGTATAGEFRYASELVSFI
RETQGKDWHIEVAAYPEVHPQQRYAAKDMQHFADKMNAGADGAITQFFFNADAYFHFVDE
ARRLGVTQPIVPGIMPFHNYGRIAQFAQRDGIEIPRWVQMKMEGFMDDTASIRAFGLDVA
AKLCERLIAGGAPGLHFYTLNQSALTLELCKRLGLDRQSPSPGLPR
>A0A2J6J7Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MNRYPSRSQRFIELLRERPLIGDGAIGTLLHSRGIALESNIEHLNLVRPEAVGRVHADYC
AAGADLLETNTFAANRLRLASIGLEKKVRRINREGARLARQAAGEDRFVAGAVGPLLLPR
GTEQTLATDEKQTLLREQMEALAEGGVDLFLLETFASLDDALLGIAVAETIGLPVVAQMA
FLDSGHSRDGISAELAATRLAEAGAILVGANCGTGPKDLLKTLQRMAVVTDTPLSAFPNA
GAPEYVDGRYLYLATPAYFAHYGVELANAGAALIGGCCGITPEHIAALKQLLPHQHTRGR
RIEITPPQPRDPQPHQPERRKTFLDSWGQRPIITVELDPPKGLDVTEIMARARELADAGI
DAISLAENPLATIRLGTLALAKKIEDEVGIDVIAHMTCRDRNLIGLHSDLMGAHLLGLRT
ILAVTGDPVSAGDDAGASSVFDLNSIGLLELLQNLNTGRSSYGAPLNGHTDFLPGAAFNP
NLERIDGQLTRLEKKIAAGARFVQTQPVYAKQHLDRLLDRTRAYDIPMLVGILPLVSGRN
AEFLHNEVPGISIPAEVRQRMQNKSGEEGMREGLAVAGELIEYGRGRVGGYYLMPPFGRI
ELALTLAEKIGQQP
>A0A2J6JBI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MSAVKTGRSASFLKALGEKVLLGDGAMGTLLYARGVALDACFEHLNLVQPELVRQVHADY
LAAGSEVIESNTFAANGVRLGAIGLAGKVAAINRAGARLAREVAGETRFIAGAVGPLSTP
RGEGEPLTAAEKRRLFIEQMEALAQEGVDLFLLETFSRLDELELATCIATELGLPAVAQM
AFLEEGRSRDGVSAEEAATRLTVAGAAVIGANCGSGPRDLLRILRRMREVTDRPLSAFAN
SGFPQYVDGRYIYLATPDYFATMAQEMVLAGARLVGGCCGTTPEHISALAKGVRQSAEET
LPSSVTATAPVVRRVVAETPVPPAHFLEAWGERPLVTVELDPPRGLDCSKVMAGAKQLAA
AGVDAISLAENPLARIRMGNIALARQIQEETGTEVIVHVTGRDRNLIGLHSEMMGAHLLG
LRTILAVTGDPVAVGGEAGASSVFDLNSIGLLELLSALNRGENLLGADLGGTTSFFCGAA
FNPNLPRIDGQLQRLEKKIAAGARFVQTQPIYDVEILDRLLEKTSPYNIPVLVGLLPLVS
GRNAEFLHNEVPGITLPEPVRQRMASTSGEEGVRQGMMLARELLAAGRGRVGGWYLMPPF
GKVELALDLLATIRAEG
>A0A1M6PXK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforamulus aeronauticus DSM 10349|TrEMBL
MKIANLFQEKKPVISFEIFPPKNTTPIESIFNTLEEMIKLNPDYISVTYGAGGSSRDRTR
EIASRIKNQYNVEALAHLTCVGHTTVEINQILKDLEAENIENVLALRGDPPADQPNYDFS
TCDFKYASNLVKHIKNSSAMSVGAAAYPEGHIHCLRLSEDLTWLKHKVDQGVDFLVTQIY
FDNRIFYNFIENARRIGITCPVSPGIMPVLNSKQIKRMITLCGASMPAKLLIMVDKYGDN
PEDMEKAGIEYASRQVEDLLNNGVDGIHLYTMNKHQQITEILKNVGKA
>M0JNJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula sinaiiensis ATCC 33800|TrEMBL
MALGTRTVSDSQGVRTLLTSARFELMPFESFDEEITHLPDNATIAITTSPQLGIEKTVEK
TAEAAEMGYDVVPHIAARYVEDREQLESIAERLEQAGITDIFVPGGDREEPAGEYESALD
MLEALEETEYSFEEVGITGYPEGHDFIDDETLAESMAQKAPYATYIVTQLCYDPDAVLEW
VEDIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVEDDEYNIRGVHIYTFNQTPDTEKWRHKRLDS
>A0A6I5CXZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4982|TrEMBL
MESVLGVSGRVGASLLDGYSLEMTGKDVPRLEEARAGIAPGTRINVTYLAGEDPGMRLAA
ARAVREHGFVPVPHLSARRLPSSAELERFLAGLAEEGAVENVFVVGGDPARPEGPYEDAL
SVIRGGLLQRYGVRHVGICGYPEGHPAIADDVLWSALTGKAAALEAAGLSGDVITQFGFD
ADAVLTWLEALRARGVHLPVRVGVPGPAGVRRLLGYATRFGVGTGAAVARKYGLSLTNLM
GTAGPDRFLDDLAAGWDPARHGTVGLHFYTFGGLRPTAEWITRYRTDRG
>A0A291E9A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia alcalifaciens|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSTEMEQTLWKSIDRLKVLKPNFVSVTY
GANSGERDRTHSIIKDIKDKTGLVAAPHLTCIDASRDELRAIARDYWDNGIRHIVALRGD
LPDNSQKPELYAEHLVELLKTEADFDISVAAYPEVHPEAKSAQADLINLKKKIEAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPSWMNRMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPQ
>A0A2T7PSE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pomacea canaliculata|TrEMBL
MTAVQRHKQLINHAMSTIDSVAHLNSVESSSVTCNTLSGIVQNHTHIRLIDRIHRRQASG
NKFFSFEFFPPKTASGTLNLFSRFEAMNLGRPLFCSMTWHPANDPSNTDKPTSSTRVAST
MQNDLGIETLLHMTCVNQTRSQVVENLRKAKDLGIRNIFAVRGDVSEGAEGHHVGGHLNY
AADLVRIIKEEFGDHFVVGVAGYPSGHPECTSYANDLHRLKEKVDAGADFIISQIFFEAE
AFLKFVRDCKAIGIDCPILPGILPIQAYQFRHIVKLAGLEVPQEIIDAMNLIKTNDEAMK
NFAIDHTVELCKTLLLDGESVPGIHFFTLNREVPTIDIVKKLGLWKEDIFRPLALKIASN
DERCKEII
>A0A1Q8ZQZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium oryziradicis|TrEMBL
MAGHLQTQALKRPFKLSFEFFPPKSEDMEAQLWETVDDLAGWEPEFVSVTYGAGGTTKAP
TLAAVRRLIGQTPLATASHLTCVGATREDVANVVEEFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGYENAAALVAGLKDLGDFEISVSAYPEKHPESADLAMDIDMLKRKVDNGATRALT
QFFFDNDLFEHYLNRVRAAGITIPIVPGIMPILNLTQLKRFASMCGTSVPAWLDDRFAGL
EDSPADRARVAAEIAAEQIADLQRRGVDEFHLYTMNRAPLVNTTLQQLGLSKPKLMVESD
AQLAVSATA
>A0A3M5HSX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. oryzae|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDGKDDLRNLLAQYREAGIKRIVALRGDLPSGMGMASGELRHANDL
VTFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A5F2DDL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira mtsangambouensis|TrEMBL
MHISQILGKKQTTISFEFFPPKNAEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEETGLTIVSHLTCVGSTKDEIREILKRYQKSGIHNIMALRGDPPKGQTEFHKT
ENGFEFAGELVGFIKKEFPELGIGVAGFPEGHPSTPNRLKEIEYLKWKVDQGVDYICTQL
FFNNNDFYDFVERCEIAGIKVPIIAGIMPITSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDVYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRRIYESLGIRNFDSIG
>A0A2S4K0S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalispirochaeta sphaeroplastigenens|TrEMBL
MAIERVSDLLGRGKTLFSFEFFPPRTEQGWNRLFHSIGTDLLPLEPAYVSVTYGAGGSTR
EYTHRLVTRIQSEFNLTVVAHLTCVGSSRAEIAGILDQYRAAGVCNILALRGDLPRQGGE
ESRRSDFSCAAELVSFVRNYMPEASIGVAGFPEGHPDTPNRLLEIEYLRQKVDAGADYIV
TQLFFDNRDYFDYVERLALAGITLPVVPGIMPVTTRKGMQRMAELAAGARFPAALLRAVE
RTHDDQGVNRVGTHWATAQVADLLNRDVPGVHLYTLNNSWSTIHICRNLGLESYRL
>A0A1W9TGR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_123|TrEMBL
MNSGSNLQKILEAGHFAFTGELGPPRGANVDAVRKKAAYLKGMVDSVNITDNQTAMVRMS
SWAASLIAIQEGLEPNYQMVCRDRNRLAMQADILGAHAHGIRNMLCLSGDHQQFGDHPQS
KGVFDIDSVQLIGMTKKMRDEGKFLGGADIDTPPEMFIGAAANPFADPFEWRVYRLAKKV
AAGADFVQTQCIYNMVKMREWVKQANDMGLTEKVYILAGITPMKSIGMARYMKKKVPGMD
VPDEIIKRLQGVDKKKVADEGIKIACEQIEEFKEMKGVAGVHLMAIEWEHKVPEIAERAK
VLPRPQVD
>L7CNX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula baltica SWK14|TrEMBL
MELLCKNVERLMQFGPKYFTCTYGAGGSSQGTTLEVLQKVKQITKLPVASHLTCVGSTVK
ELEAYLTEAGRIGVDYIVALRGDPPKGTTQFEVTEGGLKYANELVELIRGRFGDLGIAVA
GYPETHQEAVDFQTDLTNLKRKVDAGADIVITQLFYDNDDFYRFRDACEKVGIEVPIVPG
ILPVTNFKQAKRIASMCKAAIPQSLESAMTEADDDQDQFRVGVEHARQQTIDLVNNGVPG
IHYYVLNKSEAAAELLDGLSLTSR
>A0A370H2H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia mexicana|TrEMBL
MEFNPPRDAAAEARLWRAAREFERMHPAFVSMTYGAGGSTRDRTARVTGQLARETTLLTV
AHLTAVEHSVAELRSIVGTYADAGIRNLLVLRGDPPGDPLGEWRKHPDGLEYAEDLVRMV
RGLGDFHVGVASFPQGHHRSPDLDQDTAYLCAKLRAGAEYSITQMFFDVDDYLRLRDRVV
ACDPVEGAKPIIPELMPITSLRTVQRAEELSGRPLPAHLMQRLERAAGNDPEANRNAVRA
VGIEIATEIGQRLIDEGAPGLHFITLNFAKATTEVLTNLGYTVTATPVSA
>A0A7V3FVJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MKVIEHLEKATNTLISFEIIPPKRGGNVKQLLQVLDDIVKYDPPFIDITSHAAEVIYEET
PRGEMQMKVKRKRPGTLGLCALIQNKYNIDAVPHVLCSGFTREETEDFLIEIHYLGIDNV
LAVRGDDSAYKKPLKYGRSANEYAVDLVQQIIDLNQGKYIEDDLLDAEPMDICVGVGGYP
EKHFEAPNLNVDIKHTKAKIDAGASYIVTQMFFSNEHFYNYVELCRNAGINVPIIPGLKI
ITSKAQIRSLPKNFFIDIPQDLADEIEKAKPEHVVEIGINWTLKQVEDLLNHNVPAIHFY
VMQNSQPIKTLMNKLKI
>A0A8D4U453|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae|TrEMBL
MSYAKEIDRLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A7W7AIV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas abaci|TrEMBL
MTISVDQLAEARCALESPLYADVGGDLDVSFEFFPPKSEKMEAQLWDAIRTLEPLGPRFV
SVTYGAGGTTRERTHATVARIQRETSLAAAAHLTCVEATREQIIEVAEEYWAAGVRHIVA
LRGDPPQAGSRFVSHPGGFENAAALVAGLRKLHPFEISVAAYPENHPDSASDAADLDNLR
AKLDAGANRAITQFFFEPETFFRYRDKVAAAGIRAEIVPGIMPVSNFASVQRMSAMCGTA
VPPWMARLFEGLDDHPAARQLVAATVAAELSRRLYAGGVKHLHFYTLNRAELAFAICHLL
GVRAKGQVGQAAA
>A0A226Q583|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus thermocatenulatus|TrEMBL
MGLLDELKQRILIADGAMGTLLYSHGIDRCFEELNLSNPDEIIHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPGINRAAVRLAKQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGIDGVLLETYYDLEELETVLAIARQETDLPIIAHVSLHEVGVLQDGT
PLADALSRLEALGADVVGLNCRLGPYYMIQSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRAVSVS
VQAERPAPTPLPELARTRRSVIVELDPPKQLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKERIGVRPLVHMTCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLISQFNEGLSYSGKSLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPVYSEEKIVQIYEATKHLDTPIYIGIMPLVSARNAEFLHHEVPGIT
LSDEIRARMAACGDDPVQAAREGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A401IMS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanothece sacrum FPU1|TrEMBL
MINRFRQAVQNKEFLITAEITPPKGGNPTRMLDMAKGLKNRVHAVNITDGSRAVLRMSSV
AASALLLQYEIEPICQVACRDRNVIGLQSDLMGAYGLGLRNVLALTGDPIKAGDHQKARA
VFELESVRLLKLIDNLNRGVDFNNKHLPDDALDLFAGAAVDPQSPSWSGLQRRFDAKLAA
GAQFFQSQLITDFDKLDKFMHQLAAKTDKPILAGIFLLKSAKNAKFINNNVPGVAIPDSI
IQRLADASDPLQEGVKIAAEQVKLAQQLCQGVHMMAIKREDLIPQILDLAGIFPI
>A3SS69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. (strain NAS-14.1)|TrEMBL
MTSPAVSFEVFPPKSVDASFRLWDTAQALAPLAPRFFSVTYGAGGSTRDLTHDSAHVLRR
TSGLPVAAHLTCVGASKAETLEVADSFAEIGVTDIVALRGDPENGASTFTPHADGFADSV
ELIEALAKTGKFTLRVGAYPEPHPESHDQAQNVEWLKRKFDAGADEAITQFFFETETFLR
FRDACAAAGITKTITPGIMPVTNWKSARNFATRCGASVPAALDEAYAAAIRDDRHDLLST
ALCTEMCSELVSEGVENLHFYTLNRPELTRAVCRALGVTAQTSLSDVA
>A0A2E3B890|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pelagibacter sp|TrEMBL
MFNTTDFIXTSETTPDVTTDLSXCXGXVEKLIGLAXAVNVTDSPNCKSRLNSLLVASEIK
RKGLDVILQLTGRDRNQIALESVLLGALSVGINKVLCLSGDQPDENGPAVVNEFNGNGLI
ELCEXISGGTLXDGTEIKKPXXLYSGAADDLYTQISKPEALKKLVTKIEQGASFIQTQYC
FDYDVIKKYSDKLNDQGSFNXCKVXIGMGPLKSAXQGDWMRKNLWGVNISDEILLRMEES
QSPAETGEKICQELIEKIMDXPCIDGVHLMGPSCEKSSASIISYFK
>A0A0E0D8P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryza meridionalis|TrEMBL
MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVHHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLK
QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNL
GLIEESKISRPLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLD
QLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWK
DEAFEIWSKGWACLFPEGDSSREILDKVQKSYYLVSLVDNDYINGDLFAASLGYDFVFDT
>R0K2D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Setosphaeria turcica (strain 28A)|TrEMBL
MHISQKLAQAKREGKPTFSFEFFPPKTAQGVQNLYDRMDRMHSFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDDALKEAYQAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGCDDNDNVDELIDHLKEKVDAGATF
VVTQMFYDTDIFLEWVRKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTRCHIPKHWEEAL
EPIKNDDVEVREVGKTLVADMCRRLIEAGITHLHFYTMNLAQATRMVLEELELLPDVESP
LEKPLPWRPSLALNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPLSIRDLSNLFVRYMEGKIESLPWSEQAITMEASSIQKDLID
LNRRGFLTINSQPAVNGIKSSDPVFGWGPRNGYVYQKAYLEVFVSPAYIAEVITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDVIDTWYLLNIVHNDFHATRGIFPIFDGLEVKDMDKPLHVPSADL
PNANGGETNGTSHTNGTNGEQTVPRKEEKPTLIETAKAAAVEVTNGMRDIVVSN
>A0A1Z5T5S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii EXF-2000|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGIRNILALRGDPPRSDE
YNDPNNPLSEQDDSNKDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLVEKTAAGADFIMTQLFFDVEAYNNYEKRLRSHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLSRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTL
NLEKVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSS
NRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPVNSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLKGEIEA
MPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSTDPIYGWGPKNGFVFQKPF
VELFLPSADWQRLKPILQSDDQVTYYAGNAAGEFQSSDENSVNPVTWGTFAGKEIITPTI
IEADSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDA
LIAA
>A0A1M3EAA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium 43-16|TrEMBL
MKVTEHITKAQGSTLFSFEILPPLKGETVQHIYNTIDTLIDYNPAFIDVTYHREEYVFLE
RENGLLEKKVVRKRPGTVGICAAIQNKYKVDAVPHILCGGFDQEDTENFLIDLDFLGIDN
VLALRGDAIKSEIYFKSERNGHQYANELVTQIKGLNKGTYLDDYLENNNPTNFCVGVAAY
PEKHMEAASLRQDIVYLKQKIDAGADYIVTQMFFNNEAYFDFVDKCRAAGITVPIIPGLK
PIATKGQLSMIPHRFKVDLPDDLVMEVLKCKDNKEVKQVGVEWCIAQCRELKAKGVPVLH
FYSMGKSENIKTIVNEVL
>A0A351YVR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MTIKEILIKKNLVLSFELFPPKKEQSFAGVFEAAEKLSSLKPDFISVTCGAGGTTGGNTC
EVAAKINSMGIPSLAHLTCADNTRKSLLQKIQIMKDLGINNVLALRGDKKTALSDFEHAS
DIVPYLKQAGFCTGGACYPEGHPESPNLDADIDNLHYKVDAGLDFLTTQMFFDNNMLYSY
LYRLNSRGIHLPVLAGIMPVTNASQVQKMVRLSGAHVPPKLMMLCDKFSGNSGAMYQAGI
SYAVDQILDLISNGIRGIHIYTMNKANVACDIIKNLSSIFEAAA
>A0A3M0WU10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MKVTEHLAKAKDTLISFEIIPPKRGGDIKQLLSVLDEIVKYNPPFIDITSHAAEVVYEET
PSGEFKMKIKRKRPGTLGICALIQNKYNVDAVPHVICQGFTKEETEDFLIELHYLGIDNV
LAIRGDDAGFQKPVKFGRSVNHYAIDLVNQISNMNKGKYLEDSLLDAEPMDFCIGVGGYP
EKHFEAPNLRTDIKFTKEKINAGAEYIVTQMFYDNNYFYDYVDVCKEEGIDVPILPGLKI
LTSKKQVTSLPRNFFIDIPPELAEEVLSAKNEHVVDIGVEWAAKQVEDLLNRNVPAIHFY
IMQNAEPIKKLMKRLNI
>A0A225WZR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora megakarya|TrEMBL
MKIIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLDLSANAQKLSSLEMLMHMTCTNMAESDIKKALDQAKDAGIHNILALRGDPVRGASS
FDECDRGFSHAVDLVRYMREKYGDHFCIGVAGYPEGHVESKDKKADILYLKEKVDAGADF
VITQLFYDVQVFVNFVKECRAVGITVPIIPGIMPIQNYGGFERMTSFCNTFVPEEIRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRASETVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSSTSTPNERRAMWGEAPASKEDVRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
SANSAGFLTINSQPRVNGAMSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
RSVQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEEGSQSAKLLRDIHDTYFLVSIVDNDFVNGNIWDLFEPSISPVASP
>A0A2W6U7N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
MGLSLSQLHEAQSALSAPLYADVAGDIGVSFEFFPPKTEKMEQTLWDAIQTLAPLAPRFV
SVTYGAGGSTRERTHQTVARIVRETSIPAAAHLTCVDATREEIDRIARDYWEAGVRHIVA
LRGDPPRAGEAFRSHPGGYENAAALTAGLRKIAPFEISVAAYPECHPDSANPQVDLDNLK
RKIDAGADRAITQFFFSPETFFRFRDAAAAAGIDAEIVPGIMPVSTFAAVTRMAGMCNTE
VPEWMGRLFEGLDDHPAARQLVSATIAAELCRKLYAGGVRQFHFYTLNRAELAYAICHLL
GKRPAKLGGALEAAA
>A0A8I0I8A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAAKLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAIDADSDLKYFKAKVDAGADAAITQYFYNADAYFHFRDA
AQRLGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AGLCERLIAGGVPALHFYTLNLAKPTTQVLQLLGR
>A0A380JHE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus downei MFe28|TrEMBL
MSKLLDKLKTDILVADGAMGTLLYAEGLESCHAYYNISHPERILAIHKAYIDAGADIIQT
NTYDAKRHRLKSFGYDNDVKQINQKAAEIARQAAGRNVFVLGTIGASRGLRQCDLSLEDI
VKETVEQAQALLETEQLDGLLFETYYDREELEAVIKAIRPLTDLPLITNMALHEAGITED
GRPLVEALSHLVMLGADIVGLNCHLGPYHMIQSFKQVPLFAQSYLSAYPNASLLSFAGDD
EKGQYRFSQNADYFEYCAQLFVEEGVRLIGGCCGTTPDHIRAIKRGIKNLKPVERKTITP
LITEEELIDEIAKKETLADKAKKEVTIIAEIDPPKTLAIEKFIEGIKALDKKNIAAITLA
DNSLAKTRICNLSLASLLKNEIATPFLLHIACRDHNMIGLQSRLLGMDVLGFNQLLAITG
DPTKIGDFPGATSVYDATSFKLLSLIKQLNHGKGYSGASLKRATHFTTAAAFNPNVRQLE
KSNRLIERKIKAGADYFITQPIFSEEIIHQLGSLTKTYEQPFFIGIMPITSYNNAVFLHN
EVPGIHLSEAFLEKLETVKDDKEACQAIALAESKKLIDCALEYFNGIYLITPFLRYDLTL
DLIDYIQKRKP
>A0A450RUA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. DK|TrEMBL
MNTDKKPVFSFEFFPPKTPDGKNNLRAASQRLAGLGPDFFSVTFGAGGSTQSGTLETVRE
IRRETSIPTAPHISCIGSTRDKIREMLDSYRAAHIERLVALRGDLLPGMKEPGELRYANE
LVEFIREKTGDTFHIEVAAYPEVHPEAPSAEVDRQNFKRKVEAGADSAITQYFFDADAYM
DFVDNCRAIGVNIPIIPGIMPITNYTSLAGFSQRCGAKIPPRLAERLEGFGDDLDSLRAF
GIDTVTELCRKLREAGAPGLHFYVLNRAEPAITIWKNLGLS
>A0A1Z4RKD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix sp. NIES-4101|TrEMBL
MLNVMLDTLNPVSFSSFRTAARNGEFLVTAEVCPPKGGNPEHMLKMAATLKGRVHAVNIT
DGSRAVLRMSPLIASAILLQHGIEPICQLACRDRNRIGLQADLMGAHALGIQNILALTGD
PVKAGDHPECKGVFDLEAVRLLQVIKKLNLGVDYNDKPLTDGALNLFPGAAVDPQCPSWS
GLQSRFEKKLAAGAQFFQSQLITDFDRLEKFMDGIATGSNKPILAGIFLLKSAKNAEFIN
RMVPGVNIPQHIINRLAKAKDPLEEGIKIAAEQVQTARQLCQGVHMMAVKREDLIAPILD
MAGVKPVGLVAAHS
>A0A5R9AL01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter sp. ACAM166|TrEMBL
MKVTDHITNAKGKTLFSFEIVPPVKGRNIQELYNNIDPLMEFNPPFIDVTTSREETVYVQ
KEGLLDRKTTRMRPGTVGICASIKHKYNIDTVPHVICGGFTKEETEYMLVDCHYLGIQNV
MALRGDARSEQKYFEPTDGGHPFAIDLVKQIQDLNGGRYLHETVETDHTGEFCIGVAGYP
EKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVEAAKDIGITVPIIPGIKP
IAVKRHLQLLPQVFRIDIPQDLIEAVDSCKNNKEVRAVGIEWAIQQSKELKEAGVPVLHY
YSMGKSDNIKAIAKELF
>A0A270PLH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ERMR1:02|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKADLRALLSQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGNHFHVEVAAYPEMHPQARNFEDDIANFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCDRLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A3M3TAU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. morsprunorum|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A2S7KAN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinicaulis flavus|TrEMBL
MSYAEIHPNWETLSSDMLDGYSLEITAKDVPSLREAAPMIAPQTPIAVTFLPGEEMEDRI
NAVKAVRELGFEPMPHVSARRIQSQAILENMLEHVTGESGVKRIFLIAGDPPQPEGPFAD
SLQIIRTGLLEKNGIKAIGIAGHPEGHPNVSRDDLWVWMENKIAEIRDRGMLPIIVTQFG
FSADPFLEWLEEMRARGIDAPVRIGVPGPAGIKRLLGFAARCGVGASAAVMAKYGVSLTK
LMGTAGPDKLVGAIEDGLDFKKHGRVRLHFYPFGGLSKTLEWIHEHEKKRGLT
>F4VLL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli H591|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2D5V3G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVVDYIKNSNKTIFSFEIIPPLKGKGIEDICKGIDPLMEFNPPFINVTYHXEEYEYKKM
GNGLLKKVSIRKRPGTVGICAALMNRYKVDAIPHIICGGFTKEDTESALIDLKFLGVDNI
LALRGDPMKNESAFIPTDGGNKFAIDLIEQINDMNNGQYLYEETKNSPSNFCIGGAGYPE
KXFEAMNLKSDLKHLKEKVDAGMEFIVTQLFYDNKKFFEFEKKCREIGITVPIIPGLKPI
TNLRHLTFIPKFFNTNFPEEFSNELEKCKTNDEVKKVGVEWSTMQSQELVKAGVPVLHFY
TMGKGESVKNIASKIF
>A0A0B1Z2B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas frederiksbergensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VEFIREETGEHFHIEIAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERVRQMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQRFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>D7XIF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli MS 84-1|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7X7EM53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MRTSEIFKNKTVLSLEVFPPRRTAPVDIIYDTLDELRGLNPDFISVTYGAGGSENNSATL
EIASAIKNHYAIESVAHLPGIYLTKGDVLEMLDGFRQQGIENILALRGDISPECPPKQDF
NYASDLISFIKENGDFNIIGACYPEGHIECGSLIEDIRNLKIKVDAGTDQLITQLFFDNS
YFYSFRERALLAGINIPIEAGIMPVVNKKQIEKMVTLCGVKLPRKFTAMMEKYENNPIAM
RDAGIAYAIDQIVDLLAQDVDGIHLYTMNNPYIAQKIYVAISSLLAA
>A0A7X7X212|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MRLSRLFRNKKQVLSFEIFPPKPEVPLENLFDSIPGFKALSPDYISVTYGAGGSSRGRTV
EIASRLKNTYGIEAMAHLTCVGHSVEQIDQVLESLKQENIKNVLALRGDPPIDQPDFDFS
KGAFRYANELIAHIRKAKEGDFCIAAAAYLEGHVDSKRLDEDRRRLKDKVDAGVDLLVTQ
LFFDNRLYFDFLDRAAQIGINCPIVPGVMPIFNARIKTMTARSGCSIPAKLVLMIDKYQD
NPEDLRKAGIEYAGKQIRELLDGGAPGVHLYTMNRLKSTTEILEVAGLR
>A0A8H3TY99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naganishia liquefaciens|TrEMBL
MKISERFHEAARDGRTIWSFEYFPPRTAQGLQNLYDRIERMRHLGPDFIDITWGAGGKNS
DLTLNLVQVCQQTIGMETCMHLCCTEMPTEKVKEALRVAKLHGCQNILALRGDPPHGQSD
WTPPPGGFSKAIDLVKYIRSEYGDYFDIAVAGFPQGHPETPPGEDAQAKEIQYLKEKVDA
GANFIFTQMFYDVNIFINWVKRVRAAGINVPIVPGIMPIQSWQKFMTWVKRESIVVPQKF
WDVLLPVQEDDERVRAIGTKLVADMCRDILAADIGIRGLHVYTLNLEKGARMLLEELGLE
GRKEQIQPLPWRPSLTPARRQESIRPIFWANRQQSYLSRTDDWDEFPNGRWGDSRSPAYG
DLDGYPVKIDIAASEANEIWGNPETFDDIKTLFARFCLHDLRALPWSTQPPSKETSVIDQ
QLAKMNRLGYLTINSQPAVDGAASTDPTHGWGPAGGYVYQKAYLEFFVAPHLLDGLVKRI
ERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIIQPTIVEAVSFIAWKDEAFEL
GVQWAGLYPDGSESRKLIQQVMDTSYLVNIVANDFKDGMSIFEPFQLEQADSLPPLPKSV
AAAPASGTTTIAGVAQTIKASANAVKESAQSAISSVQDKVLGNGSAIPKANSDSSADTGR
LATPTVNGGVAKENGTASSYDVDDSTKSDANGPEPADANAAKGGSVDVNGNGNAKEGVNG
TGRLATPPVNETKDNGASKPTGDEAKAADTDMLDEMPAISESEISAAVELRMNDLLRPGP
TPRKRYTPADLDTLFDDIPLFMRDNDKAAASENDTLEALKTLVFEGNGDEVALNFKNHAV
ENHQQGKLREALAQYTQGLDAKPEDPKLIESLLLNRAACNLSLGNNGSVLRDTSAVLKLN
PDSPKAYFRAASALLSLSRYEDALICVDHGRKLKSEQEDSKQAMWQGLQDKAKKGLRVIN
EREERLRREKLGKEALQQAIRARGILQVKTAAPPDNPNPAGFAPDSVPDVPLTPPEGITW
SPPSLSTPLVFPAFFLYPTVQNSDLITQFHEDSTFYDQLEAMFPVSADGTAAHEGVTWAD
WDQAHQFRSDNLSIYAITHAKKLLKVGRNHTLRQVAEKAASLSTPAQRDGLFMQDGLMSF
IVLPRGQAEQDWIERFKADRDGASSGN
>A0A7Z6QY34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cereibacter sphaeroides f. sp. denitrificans|TrEMBL
MARPRISFEFFPPQTLEASFRLWETAQMLAPLKPDFVSVTYGAGGTTRKLTHEAVETIHN
HYRLNVAAHLTCVDATKAETLEIAASYAEAGVTEIVALRGDAPKGADRFTPHAEGFASSV
ELVEALAATGRFKLRVGAYPEPHPDAADTLADVRWLKRKIEAGATSAITQFFFEAETFLR
FRDLCAKEGITAPIIPGILPIENWSGVKKFAARCGAQVPGWLDDAFDHAKRDGREELFSV
ALCTELCDRLLSEGVEDLHFYTLNRPTLTREVCHALGILPEVALQNVA
>A0A0C1QR81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter soli|TrEMBL
MTFLERLHDEVLIGDGAIGTMLYAKGVSLDANVEHLNLVRPSLVLELHREYLAAGARVIE
TNTFGANWTRLAAIGLDKKEREINLRGARLAREAAQGTDAFVAGSVGPLVRVKGDERELS
AQETVDIFRRQTHALAEGEVDLLILETFTDLAQMRHALTAARETGLPVVANMAFLENGRL
AGGIEVERVALELTAAGACVVGANCGAGPLEILGTIQRMGRVTELPLAAYANSGFPEYVN
GRHVYRTTPDYFADRAVEMVGAGAALVGGCCGTTPEHVRRLAERLAGLRPVARTVAVPAL
PKEARRAESRDDAGFLARWGREPIVTVELDPPKGLDCAKIIEGSRALREAGADAINIAEN
PLARIRMGNIALGSLIQREAGIDVIVHVTCRDRNLLGLQSDLMGASLLGIRHVLAVTGDP
ARIGEQAGATSVYDLNSFGLIKLLADLNAGVNALGSPIGGGTGFVIGAAFNPNSPRMEVQ
VERLARKVANGARFVQTQPLYDVARLEEMAERTAHLGVPILPGILPLVSERNCEFLHNEV
PGIVIPEEIRHRMRGKEKEDGVREGLAIAREFIDAVRDRVGGFYLIPPFGKYGIAVELTR
YIKGT
>A0A7X8JDQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKIIDMFRQKKPVISFEIFPPRPDVPLETIYHHLDKFEALQPDYISVTYGAGGSRKGRTL
EIAERIKKQHKIESMAHFTCTGHTKEEISDMLCAMHDSGLENILALRGDPPAGQPDFDFS
RSAYRYAYELIQHIRGVNDFCIAAAAYVEGHVESKRLSEDLTHLKEKVDAGVDFLITQLF
FDNRLFFDFIEKTRAIGINCPIAAGIMPIFRADQIKSITAKSGCSIPASLVVMMDKYQDD
PEDMRKAGIEYASRQIMELMEAGVDGIHLYTMNRPKSTKEILSNIGDVP
>A0A6I2SRD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
MTLRERLKNEVLAGDGAIGTMLYAKGVGLDANFEHLNLVRPQLVLELHAEYLAAGARIIE
TNTFGANLTRLQPIGLAHKLAEINRQGALLARRAAGTEALVAGSVGPLVRLKGEERELSA
DEQQEIFRTQVNALADGGVDLLLLETFSDPAQLCHAIAAARTTGLPVIASMAFQEGGRTA
CGCTAEQVAMTLTAAGADAIGANCGAGPLEVLRTVQRLAAATDLPVAAFANSGFPEYVEG
RHIYRCTPEYFASMAEEMVAAGATLVGGCCGTTPAHIRAVADRLKGMRPALRSRVPRSEP
SPAAREEQREPAGFLADWGRRPVITVELDPPQGMRVDKILAGSRALKEAGADAINLAENP
LARVRMGNIALGSMIRQEVGIEVIAHITCRDRNLLGLQSDLMGASLLGVRTLLAVTGDPA
RLGDQAGASSVYDLNSFGLLKLMHDLNTGVNALGQPIGQGTGFTIGCAFNPNSPKPEVQV
ARLEKKIAAGARFAQTQPIYDREILLEMTEQTRHLAIPLLPGILPLVSERNCEYLHNEVP
GIVIPDHIRRRMRGKEKEAGVREGLAIAREFIDGVRHEVGGFYLIPPFGKYELAVELIRF
IREGR
>A0A238LHF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavimaricola marinus|TrEMBL
MTRPSVSFEFFPPKNLEGSFRLWDCVNTLAPLDPSFVSVTYGAGGTTRTLTHEAVGTIHK
TSGLTVAAHLTCVDATREETLEIAQSYADVGVTEIVALRGDPPKGAGKFTPAKDGFASSV
ELISALADTGKFRLRVGAYPEKHPDASDQQQDIDHLKRKIDAGAHSAITQFFFEADTFFR
FRDACVKAGIDAPIIPGILPIENWAGCQRFAAMCGTSIPQIVTDAFTNATRDGTTDLLAT
ALATELCDNLLRGGVDHLHFYTLNRPELTRDVCHALGVTPKASLQEVA
>A0A3A8KW92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus sp. CA053C|TrEMBL
MKIRNCLNPSQPCFSFEFFPPKTDAGVASLLRTVEELAPLNPGFVSVTYGAGGSTRDRTV
ELVTHIKQHTGIEAMAHLTCVGHTRDELRDVLRRLAAARIENVLILRGDPPQGQQTFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVSALRARS
>A0A436AFZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.001.01.1.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLEICAERSLEARVVSQF
AFDGDTIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A397LI37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium MAR_2010_72|TrEMBL
MKVTEHIKQANGKTLFSFEIIPPKKGNSIQELYNNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDRKITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIENV
MALRGDAMSHQKYFEPATGGHTYACELVKQIQNLNHGKYLHDVIEADDKADFCIGVAGYP
EKHIEAPSLKSDLKRLKEKVDAGADYVVTQMFFDNKRYFKFVEAAQQAGITVPIIPGIKP
IAVKRHLQLLPQVFKIDLPEELIYEVEKCKDNKAVRQVGIEWAIQQSKELLEFGAPVLHY
YSMGKSDNIKAIASQLF
>A0A0P1I1W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria denitrificans|TrEMBL
MTTPEISFEFFPPQTLEASFRLWDTVQTLAPLEPRFVSVTYGAGGTTRELTRDAVSTLHK
SSGLQVAAHLTCVDASRQETLEIADTFSRAGVQDIVALRGDPPKGQDRFAPHPEGFANSV
ELIEALAETEMFSIRVGAYPDKHPEAQDFSADIDWLKAKLDAGADEALTQFFFEAETFLR
FRDACGKAGIDKPIVPGILPIENWKGARNFARRCGAHIPDWVENAFEKAIRDDREDLLAT
ALCTELCSDLIDEGVDKLHFYTLNRPELTRDVCFALGITPKAELQNVA
>A0A518IZ46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rosistilla oblonga|TrEMBL
MSLSQLFRGGGCPISFELFPPRTPAGFESLYQHVDSLKQFDPAFFTCTYGAGGSTRDSTL
DVVREVKRRTGKPVASHLTCVGSTQDQLRSYLTEAGTLGVDYIVALRGDPPKGETSFTAV
EGGFRFANELVEMIHAEFPEFGIAVAGYPEVHQEAVDADVDMENLKRKVDAGADCVVTQL
FYDNDDFFRFRDACQAAGIEIPIIPGLLPITNFAQAQRIASMCKAKLPQGLVDRFNENDS
AEWQLKVGIEHAQQQTNDLIRRGIDGLHLYVLNKSQAAAEVLAGVDRG
>A0A7L0WHB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alectura lathami|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKKLGLKNIMALRGDPVGEEWEEEVHGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLKYLKEKVLAGADFIITQLFFRSETFLK
FMKDCQDIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSAREDLL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A8F8B6I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MTM4|TrEMBL
MTSLNRPSISFEFFPTKTEAGHEKLLATARRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKQELRELLNLYKEAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGASSAITQYFFNADCY
FYFVERVRKLGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMPSIQA
FGEQVISEMSEKLLAGGAPGLHFYTLNQAEPSLAIWDNLGLSR
>A0A1Y3TGK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilimicrobiota sp. An80|TrEMBL
MKISEILKKKATISFEVFPPKNKEGDISSIYYTIEELSQLNPDFISVTYGAGGSTKGKTV
EIASTIKNQYNIEAVAHLTCISSTESEILDICQQLKDNHIENILSLRGDYPQDGLQHELS
FHYAKELNTFISQHFPGDFCLSGACYPEVHQEASCLEDDLKALKEKVDAGAQYLITQIFF
DNHYYYRLVKEARKRGINVPILAGIMPVTHSKSLLRTAKLCGCSIPYELSTMIESYYHYP
EAMKEIGINYATHQIIDLITNGVDGIHIYTMNKPEIAKAIFQSIPTVLKELNHE
>B6H6J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPVEKVDQALQAAYKAGCTNILALRGDPPREKEA
WEAAENGFCYAKDLVKYIREKYGNHFDIGVGGYPEGADDNTDVDQLIDHLKEKVDAGSSF
VVTQMFYDAENFIEWVKKCRAKGINVPIIPGIMPIQTYASFIRRSNWTKVKVPSEWMEAL
EPVKNDDSAVRDIGKTLIANMCRQLIAAGIKHLHFYTMNLAQATQLVLKELELTPSEDSP
IQRPLPWRPSLGLGRRSEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISDIFVNFLTGKLDRLPWSDSPITTEAHEIQEDLLK
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKND
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCHDAASPSRQLIQHVMEDWYLVNIVDNDFHRSNAVFELFNGLEIKDLNVEVTGKPLTNG
HAEPNGVAAN
>A0A520MN26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thioglobus sp|TrEMBL
MPTEQIGNEGRPLPVLKGHDSPGRLERLLRAGKFAVTGEIAPPDSAAPEEVYERARIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRQGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVA
NILCLTGDGVQAGDQPSAKPVFDLDCMSLLEMVTSMRDQSQFLSGRRLSSPPRVFLGAAA
NPFGPPLDYRPLRLQKKIAAGAQFIQTQYCFDIDRFRTYMNQVREMGLTERCYILVGVGP
MPSAKTAAWIRDNVPGVHIPDEIIRRLLGAKNQREEGVKICIEMIQAVREIQGVSGIHIM
AYRQEERIPEIVTEAGILEGRSPWYPGIKTDHI
>M4TQE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis Xac29-1|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A2A6MJQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. NG07B|TrEMBL
MSPDINPFDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHEATPTETLVAERLEHLRGGIEENQQQMAEAAAH
HPH
>A0A133NGE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIRSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A1N6H9Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasphingorhabdus marina DSM 22363|TrEMBL
MTDHIPPLGLSQLEEAKRAIDTPLFAGLNGDADVSFEFFPPKSEKMEKTLWDSVITLEPL
APRFVSVTYGAGGSTRERTHATVARIAKETRIPAAAHLTCVDASKAEIAQVAEAYWESGI
RHIVALRGDPPAEGAKFVPHPEGYASAADLVAGLKEIAPFEISVAAYPETHPEANCPQSD
LDNLKRKLDAGASRAITQFFFTAEAFFRFREEATKAGIDAELVPGILPVSNVAQTRKFAG
MCGAEIPGWMNDLFEGLDDHPAARQLIAATVAAELCRKLYAGGVRQFHFYTLNRAELSYA
ICHLLGKRPEGKAEEKAA
>A0A2T0WG95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mongoliibacter ruber|TrEMBL
MKITEYINQADKPLFSFEILPPLKGQSLNDLLVGIEPLMEFEPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFHVEAVPHLLCGGFTKEETENALIDLNFIGVQNV
LALRGDAPKNEGKFVPEPKGHEFTTGLVQQIIGMNHGKYLHEETETSFHTDFCVGVAGYP
EKHFEAPSMKFDLKFLKEKIDAGAEYIVTQMFFDNEKYFDFVKKVRAAGIDVPIIPGLKP
ITTIGQITMLPRTFFLDLPDDLLDDLMKCKTNADVKQVGIEWAIQQSKELIANGAPVLHY
YTMSKADTTYKIAKEVF
>A0A3E2C6J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNAAGVFNHASDL
VSYIRSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWG
>T2I1W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum CECT 7347|TrEMBL
MFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTISKEYG
IPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLVSYIR
SVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFLDKAR
AAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGILYASE
QIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A2M8C215|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG_4_9_14_3_um_filter_45_9|TrEMBL
MKTKSNLERVLESKNFAVTGELGPPQSADPEVIRRKARILKDHVDAFNVTDGQTAVVRMS
SWAACLIGKEQGLEPIVQMTCRDRNRIALQMDVLGVAALGINNILCLTGDHQKFGNHPTA
KGVYDIDSIQFVKMVKDMRDEKKFQCGEEMPVEPRLFIGAAANPFADPFEFRVIRLAKKV
AAGADFIQTQIVYNVDKFAEWMKMVCDKGLHEKVKILAGVAPIKSVGAARYMKTKVPGMD
VPDSVIERLRGVTKEQVPKEGIKLCVDIINQVRQIEGVAGIHLMAIEWEEAVPEIMEAAG
LLPRP
>A0A2G2GCR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp|TrEMBL
MFEELINNLQNGKHITLETTPSHSPVFQPIIDKIKDLGLDKLVDGFSTTDNPLAKLKYSA
ILAAIKLQNAFGKPVLATMSMRDKNRIALQSDLLGGNEFDIRTVLALTGDSAAMSDQPNA
KGVFDGNSSLLLDMVSCLNSGIDYAGKPLAVKPKPIYPFAVTNSFSNNPKNIEKKMRKKI
EHGAVGLISQPVYDLDNAKQLLELLENAKSDCCESAQKAQLVIGIFPITRLRTAQFLASH
VPGIHVPKIWIESLRKANEISPEEEYKVGFELSKNLFDDIMKLHPKVHLMTANKFDLAKD
ILS
>A0A3G5KEY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pseudotuberculosis|TrEMBL
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIAIDYWNSGIRHIVALRGD
LPPNSGKPEMYACDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFD
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A2C5ZLD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps australis|TrEMBL
MEKKITDKVAALPAGSEYFSLEFFPPKTAMGFANLRHRLQRMEQALRPLFVTVTWGAGGS
TATKSLELAELCQRELGLTTCLHLTCTNMSRRCLDKALDDAKAVGIRNLLALRGDPPRRD
EYHDASDSEDDVDFAWAADLVRYIRKNHGDYFCIGVAAYPEGHGEGSCPADQSLHKDLSY
LVDKVRAGADFILTQLFFDVDAYDSFEKVLRDHPSAVFKTLPIIPGLMPIQSYQMIKRTA
RLSHASIPDDMLQRLEAVRADDEQVKMVGVDIISEMVERLRAVKSRTSNRNGYHFFTLNL
EKAVSFIVERTGLIPDSFGEEEAVVDDSSRLALPVVQINGSSSSRGRSHSRSSRRLSSVG
SDPHNRVIVGNRPLTHPEWEATGLEAGVPADNINSRANTLAISEGEGVLGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLRMSPRETLRFFGVPRTRSDVDALFVKYLRGELDQLPWSE
EKLMPESSKIRAQLEELNSRSLWTMASQPAVNGAPSSDATFGWGPAHGFVFQKAFVEFFL
SSAAWHQLLARLRSAEVRDSVSFYAANNKGDFVSSDSSGGINSASLQASTNAVTWGVYPG
KEIVTPTIIEEVSFRAWSEEAFAIWGEWAKVYGRGSESEKLLKSLQDDCWLVNIIHHDFV
DGDALWKLLSEQRLD
>B0UTC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Histophilus somni (strain 2336)|TrEMBL
MSYTKELDTLNHHMVDINGKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHTVVKRIKQETGLEAAPHLTGIDATPEELKAIAKDYWDGGIRRIVALRGDEP
KGYIKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANLVIT
QFFFDVDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPSWMAKMYEGL
DDDQTTRNLVAASIAMDMVKVLSCEGVKDFHFYTLNRSELSYAICHTLGVRPSL
>A0A4P7N2A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnaporthe oryzae|TrEMBL
MHIRDMLAETEKTGKPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVTQAQTYFGLETCMHLTCTDMGVEKVNDALSKAYKAGCTNILALRGDPPRDKEK
WEAAQDGFNYAKDLVSHIRKTYGDHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGRVRERGITVPIIPGIMPIATYASFLRRANHMQARIPEEWLQRL
EPIKTDDAAVRIVGRQLVVELCRKILAAGIHHLHFYTMNLAQSTALILEDLDWLPSPNKP
LKHALPWKQSLGLGRREEDVRPIFWRNRNKSYVMRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLLGTNEQNRKKFGEPKSVKDIATLFVRYVQKEVDTLPWSESPLDAEAEQIRDDLID
LNLRGLITINSQPAVNGVRSTHPIHGWGPPNGYVYQKAYLELLVHPAIFEQLKERIHDHP
DLTYYAVTKSGNLHTNATYEGPNAVTWGVFPGKEIVQPTVVENISFLAWKDEAFQLGMEW
ARCHDQNTPSRILIQSMMQEWYLVNIVNNDFHAPRTIFDTLKGLTVPDIDTEIVPPALPT
AVPEAAAINGERNGERNGAQANGATAAVTAS
>A0A1H7Y2J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius tolerans|TrEMBL
MKTPRISFEFFPPKTLEASFRLWDTVHTLSPLDPRFVSVTYGAGGTTRELTREAVGTLHK
ATGLNVAAHLTCVDASREETLEIADQFAAAGVTELVALRGDPPKGSTGFTAHPQGFGDSC
ELISALAETGKFTIRVGAYPEKHPEAADSRADIDWLKRKIDAGATEAITQFFFEADTFFR
FRDACVAAGIDAPIIPGILPIENWTGARKFATSCGTQIPAWLDDCFDKAIRDDRHDLLAT
ALATELCSDLIEGGVEDLHFYTLNRPELTRDVCHALGVTPRVTLRDVA
>A0A3P3XJ54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured spirochete|TrEMBL
MPVIKMCQRNMSKALLCFPESNIYAIVLCTMKSILQVIKEGRPVLFDGAMGTELYKRGVF
INRCFEEANLAAPELVLSVHRDYRDAGAEVLTTNSWGAGRYKLARHNLQDHVQEINKQAA
SLARQVAQDSLYVAGSVGPLGPRLEPVGALSEHDALDAFREQMEALIGGGVDFILLETFG
DAAEAAQAVRAARSIATSVPVFASMTIDMSGNPLFGLTLEEAMDRLIEAGADVIGLNCSV
GPQPMLRAAKRMHSHRSDIPLLIEPNAGMPRQIEGRMMYMSTPEYFATYTKYYLQEGVRF
VGGCCGTTPDHIRSMARTVRQYRAMCKDHDFAGEECAGKGLGDRGPGGRGPSEISGAGKI
VSFVPIGSKSGGAKPEAGKAEVERIPFAEKSQLAAKLARGQMVYSLELVPPSGTTLDTII
DKARIAKQAGIDAINIPDGPRATSRVSTLVTAIMIEQQVGLETILHYTCRDRNLISMQAD
LLGAHAIGLRNILCITGDPPKLGDYPDATGVFDIDSIGLTRMIYRLNGGFDISGKPIGKP
TGLSHGVGVNPGRANFETEMERFRKKIDAGAEWAITQPVFDRAVMEEFLDYIERNGLHIS
IIMGIWPLSSLKNALFMKNEVPGIEIPDEVIQRMEHCASAESAREEGVAIARELYESLKG
SIQGVQLSAPFGRIDLALRVIGK
>A0A0E3PCC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina siciliae HI350|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRYSVPLEDARHLKGLADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDFPSCGDHPGSKP
VYDLDSVQLIELVRKLDSGVDLAGNQLDGGTSFCAGAVSSIDPEKILQLIKLEKKVRGGA
DFIQTQAVYDVGVFEEFTEAVNHLEVPIIAGLIPLKSLGMAEYMNKNISGIHVPDEIMLR
MKEASSPLEEGLLIASETVKELTKLSRGVHIMPIGSHKNTPKLLSMAGISEI
>A0A7X8SU79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. P38BS-XIX|TrEMBL
MSQIDENPLGVHLPLDPLPGHYSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLTEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEMVHDSGVLKGRQPWKRESSRTDALVAERLHQISEGREENQQAMAELAA
HHTPQQTH
>A0A4R9H783|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira andrefontaineae|TrEMBL
MKKILEIYKTAKAPVYSFEFFPPKTPEGETKLFEAVEELSKVDPGYITVTYGAGGSTRDK
TIRITSELAKKFSLPAAAHFTCVGGNKEEIRVILKQIRESGIENLMALRGDPPKGEEAFK
KVEGGFGYASELISFIKEEGFDFCMGAACYPEKHPEAASLESDVDNLKRKVDSGASYLVS
QLFFKNSNFESFLDLIRKKGINVPVIPGIMPITSFTQIERFKAMAACEFPEKLVSDLEEV
KDRPEEFYKRSVNFSVNQCRELVKLGAPGIHLYTLNQSPASLDIVRELKN
>A0A1Y0GZX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium Uphvl-Ar1|TrEMBL
MRIIDHLAGEKPCFSFEFFPPKTEKGEASLFGAIRQLAELEPGFVSVTCGAGGSTREKTV
DWAGKIKHEIGIEPVVHLTCLGVPEGEIRETVDSIQGLGLKNVLALRGDMPMDGSEVGEG
YCQFASDLVGLVRETMPDACIAAACYPEKHTEAASKQSDLEAMKRKADAGVDFFITQLFF
DNDKYFEFVGRARSMGITQPIVPGIMPIQGVAQVRRFTSMCGASIPSHLLKLLDQYELAP
AAVYHIGVAHAIAQCTELLGAGAPGIHFYTLNKSPATRVVVEALKSEK
>A0A3S0C2N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC01280|TrEMBL
MALGTASVRSDRARTVREILAAGGTSYSFEFYAPRTAKGEQVLWNAMRRVEAVGPSFVSV
TYGAGGTTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNVLGQYADAGIRNMLALR
GDPAGDPLGEWIEHPEGVLYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPESYLRLRDSVAKAGCETPIIPEVMPVVNVKTLDRLPQLSNAAF
PADVKDRILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A3D9BV84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosalinus sediminis|TrEMBL
MAEDQAPAARASQPTDALLRRLAESGGAVPLSFEFFPPRTEARRTAVLEAADHLAPLAEH
GFSVTMGAGGTTRTGTHDTAVAVAERTGRPVTAHLTALGLSKAQALETADRLRQAGIRRI
LALRGDRPRAVQGPLPPGFPHASDLVAALSARHDFEISVAAHPETHPEATSPEADIDHLK
RKLDAGASVAYCQFVLDPALYGRFLDACARRGIDAPIVPGLMPLEGWTRVRSFARANGAT
VPDWLDRLFREGEAQPEVAPALAAAATLEQARRLIAYGAPALHVYTMNRWPLPVAIARLL
GHG
>A0A1F3YRH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RBG_16_64_18|TrEMBL
MESQKKHPRTFSFEFFPPKTPEGVQRLSTTWRQLAQLKPRFFSVTYGAGGSTRDRTLATV
LEIKQAGFDAAPHISCIGSTLAEIDETLDLYRSKGIRHIVALRGDLPSGAASAGELRHAN
ELVQLIRERSGDHFHIEVACYPEFHPQARSAQEDVRNFKRKVDAGANSAITQYFFNADSY
FRFVDDCEAIGIGIPIVPGIMPIGNFSQLARFSDACGADIPRWLRLKLAGFGDDAASIRS
FGLDVVTDLCDRLLSAGAPGLHFYTMNQAGPTSTIWQRLGL
>A0A0H3WYK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea faecigallinarum|TrEMBL
MTQPSFSFEFFPPKTADGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQRGTLDTVIEIQR
EGVDAAPHLSCVGSTRENIRDILGTYRDHGIRHIVALRGDLPSGMGEIGEFRYASELVEF
IRAETGDWFHIEVAAYPEYHPQAKSPRLDLEHFANKVKAGANAAITQYFFNADAYFRFVD
DVSRLGVNVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VSALCERLLREGAPGLHFYTLNAASATKAMWQRLGL
>Q30BY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Homo sapiens|TrEMBL
VKFLVTQLFFEADTFFRFVKACTDMGITCPIVPGIFPIQ
>A0A7L8VN39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. SEMIA|TrEMBL
MSGAMTDLTIPARNEGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVT
YGAGGSTRERTHSTISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRG
DPAGGIGTPYSSHPDGYQSSAELVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLQA
KVDAGATRAITQVFFDNDLYFRYLDRVRARGISIPIVPGIMPMHNFKQARNFVTRAGTTV
PDWFAAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLG
IRAKSAQKAA
>A0A291JP85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus nepalensis|TrEMBL
MSQLINKLKQNILVADGAMGTILYSDGLDTCPEAYNLTHPEKIERIHRSYIESGADIIQT
NTYGANFEKLKLFGLEHKVKDIHKAAVQIAKKAANNETFILGTVGGFRGVKQEPLSLEAI
QYHTEIQVDTLVEEGIDGLLFETYYDLEELTNIIKATKQKHNIPIVAQLTALNTNYLRDG
TEINTALQQVVNSGADIVGLNCHHGPHHMQQSFSHIELPEHAYLSCYPNASLLDIENSQF
KYSDNAEYFGKVAKQLINEGVRIIGGCCGTTPEHIQFIKSSIANLEPVTHKNVIPIKKYN
SCSRTQTKQQNLTTKVKQRPTIIVELDTPKHLDTELFFRNIKKLDDAHIDAVTLADNSLA
TVRISNVAAASIIKQQYTIEPLVHITCRDRNLIGLQSHLLGLSLLNINEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNKGINTDGDALKTKTNFNIAGAFDPNVRKLEGSVKR
AEKKIESGTHYFITQPVYSTEKIKEIYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEAILEQFEAVKDDKEKTKALSLKLSKELIDTVHKYFNGLYLITPFQKVDYSLELASY
SQSITSSKQEAIL
>A0A845EKB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacillus litoralis|TrEMBL
MDLREALKHKTLIGDGAMGTLLYSYGIDRCFEELNLSHSEEVLNVHRAYVNAGADVIQTN
TYGANYIKLERYGLQDQVKEINTAAVKLAKQAAGEAPYVVGTIGGVRGARKQAISTEEIK
RSFREQLYCLLFEQVDGLLFETFYDLEELITVLKIARKETDLPIIAQVSMHEAGVLQDGT
PLPDALEQLEGLGADVVGVNCRLGPYHTIQSLEDVPLPEKAVLSAYPNASLPAYQDGRLV
YPTDPVYFQKSAQSLFEQGARLIGGCCGTTPEHIEAIAARVKGKPPIKDKVVPIKEKTEV
RASETKDGRPHLHEKAKKGRSIIVELDPPKKLKTDRFLKGAKALHEAGVDSVTLADNSLA
SPRISNTAMASIIKQRYGIDPLVHIACRDRNLLGLQSHLMGLHALGIRQLLAVTGDPTKI
GDFPGATSVYDLNSFDLVHYIKQMNKGISFSGKNLGESTSFSVAAAFNPNVRNLNRAVGR
LEKKIKYGADYFISQPVFNEEQIIEVYEATKHIDAPIYIGIMPLTSARNAEFLHNEVPGI
TLAPEVLEKMELAGSDKEQAQAEGLSISKSLIDTALDLFNGIYLITPFLRYEMTVELTNY
IKQQTAERERKISNGIHIV
>A0A8H3YLU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Venturia inaequalis|TrEMBL
MGIPKPMRLLAFISLGIFFYVCFLMFSSPLELQVPGTGKIEKMTKDPNLEPTGEPPEPLR
RVVGSNYAPNNPNSERINATLLALVRNNELRDMLQSMRDLERTWNHKFNYPWLFLNDEPF
TEEFKTAIRGATKAEVKFELVPKDHWETPSWINDDLYQESVKVLKEQGVQYMDKKSYHNM
CRWNSGMFYKHPALLEMQYYWRVEPNVHFFCDVDYDVFRYMQDHNKTYGFTVNLYDNPES
VAGLWPSTQQFIADHPEYVHPNSAIKWLQDDTMRRENYVKANGYSTCHFWSNFEIGDMSF
WRSKAYEEYFQHLDRAGGFFYERWGDAPVHSIGLGLFEDQNKIHWFRDIGYQHIPFFNCP
NSPKCSGCVTGRFTDGEQWLNKDDCRPAWFKYVGMASTLNMEKITDKLAALPEDGTYFSL
EFFPPKTTAGFANLQARLERMSRALRPFFVNVTWGAGGSTATKSLELAELVQRQLGLTTC
LHLTCTNMNKSLIDSALERAKAIGVRNILALRGDPPRNEESFNLFYFF
>A0A5J4JIP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. JC-7|TrEMBL
MDLLETLQNRILVADGAMGTLLYAYGADTCYEEFNLTHPDDIHAIHRFYIEAGADVIQTN
TYSANYIKLAQYGLEEKVSDINKEAVRIAKQAANPSTFILGTVGGIRGHRKTEATLPEIK
RTFREQIFHLLSEGVDALLLETYFDAEELFTVVDIAKKEADVPVIAQFSLVEPGVLQNGT
PVAQAFKELENRGADVIGLNCRLGPHHMIQSFEEIPLPEHAYLSAYPNASLLDYEDGRVT
FTNNADYFKTCAAKLVEQCVRLIGGCCGTTPAHVKAIAEGIKGLAPVTEKTVRPPKIEIA
VTAQHREPPLHEIAKKRRSIIVEFDTPKTLRTERFFEGAKALHDAGIDALTMADNSLASP
RISNIAIAAILKEKHGIRPLVHITCRDRNLIGLQSHLMGLAALGIDQVLAVTGDPSKIGD
FPGATSVYDLSSMDLIAMIKQFNEGISYSGKSLQRKSNFSVAAAFNPNVRNLDKAVGRLE
RKIRSGADYFITQPVFSEGKILQVHEATKHLDAPIYLGIMPLTSYRNANFLHNEVPGITL
TDEILTAMEKTQGDPLKAREESLAISRSLIDAALGYFNGIYLITPLDRYDLTVECTRYIH
AKEEKARGAGIV
>A0A3P1USP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucellaceae bacterium VT-16-1752|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKSEEMEQRLWETVTRLAPLQPEFVSVTYGAGGSTR
ERTIRTVARILKETDIKPAAHLTCVDATREEVDRVVREFADLGVSRFVALRGDPAAGIGE
KYVPTTGGYLNGADLVGGLRQIADFDISVSAYPEKHPESPDFATDIDMLKRKVDAGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPAWLAERFD
GLENDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPYAICHMIGIRPKTEAVL
EPA
>A0A3D1Q7Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas sp|TrEMBL
MARLKGLTVGEIVQKTAQPQAFRVKVPLENPLTDKIKQGKKVLAVELDPPIDTDIDFFME
GAQLLKQAGVDAITIADCPLARARVDSSLMACKLKRELDITPIPHMTCRDRNINATKALL
LGLSIEGVNNVLVVTGDPVPTAQRDEIKGIFSFNSAVLAGYIRNLNETVFSSPFNICAAL
NVNARNFGSQLQRAQKKIAQGVTMFLTQPVLGRQAVENIKKARQELNASILGGILPIMSH
RNACFMNNEVAGIYVAEEIVEQYRDIPREEAHRLAVEVSIDMASQIYDYVDGYYLITPFK
RVDIITAIIAGIRNLTV
>A0A0Q9ZQE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salegentibacter mishustinae|TrEMBL
MKITEHIEKAKGRSLFSFEILPPLKGQNIQSIYDGIDPLMEFKPPFIDVTYHREEYVFNE
KENGLLEKRIVRKRPGTVGICAAIQSKYGVDAVPHILCGGFSKEDTENFLIDLDFLGIQN
VVALRGDAIKSETYFTPEPKGNKFAKDLVEQIMEMNRGNYQDEVIEKGHNTNFCVGVAGY
PEKHMEAPSLDKDICRLKEKIEAGAEYVVTQMFFDNSKYFEFVDKCRESGISVPIIPGLK
PLATKRQLSIIPHRFHVDMPEDLISEVEKCKDNKEVRQVGIEWGIKQSKELVKAGVPVLH
YYSMGKSTNIQKIAKAVF
>A0A1V6H279|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotogae bacterium ADurb.Bin062|TrEMBL
MSERIVDIFENPLPSYSIEVFPPKPNLEKTLEIIFDTIDRLKVIDPSFVSVTYGSGGYNR
ERALSIAGHLIQGAYRALSHITAVGYLRSDIVDLLDQLYYLGVRNVLALRGDIPPNLIFP
DTELDRFRYAYDLIDFVKRDGRFCIGAAAYPEGYADSGDVDLSVLYLKKKAEVGADFFIT
QLFFDNARFYRFLEKARAVGISQPIVPAIMPILRNTNLKRILSLSSTSLPSGLQEKIDRF
GADPLDLEKVGIAHAAKQVQDLREHGMKHIHLYTMNKSKQIIEICRLSETVSKSEGR
>A0A1V4S157|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4484_190.1|TrEMBL
MVSSFKKTLESGKFVVTSEVAPPKGTNLEKMVHHIELLKDKVDAVNVTDHQSSVMRFPSL
GGGLLIKEMGGEPILQMTCRDRNRVALQADLLLAASRGINNVLCLTGDSLLLGDHKEAKG
VFDLDSSQLLAAIRRLEKGKDLGGNDLDGAVSFCAGAIVTPEANPLEPQLIKFEKKVEAG
AKFIQTQAVYDLDNFQRFMDYAKQFPVRILAGIILLTSAPMARFMNKNVAGVNVPQELID
EMASAPKGRGIEKGIEVAGRMIKQIQQKKMCDGVHIMAIGREELVPDIMSAGGLL
>A0A4P7XF69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrocarboniclastica marina|TrEMBL
MQSQKQFERRFSFEFFPPKTDAGVEKLQQTRDELAERKPSFFSVTFGAGGSTRDRTIETV
LKLHKQGISTAPHLSCVGSTRESVAELLDIYRDNGVNRIVTLRGDLPSGMGSAGELRYAN
ELVAFIREHSGDHFALEVAAYPEYHPQARSAEEDLKNFQRKVEAGANSAITQYFYNPDAY
FYFIDRLEKAGITIPVVPGIMPIVNYSSLIRFSEMCGAEVPRWIRKQLDAYGDDSESIRK
FGEEVVTEMCRKLLAGGAPGLHFYTLNQSTPSLAIWDNLALAPEPKISF
>A0A4P8T1R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SGAir0924|TrEMBL
MALGTASTRTDRARTVRDILAAGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVELIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEIMPVTSVKMLERLPKLSNASF
PAELKERILAAKDDPAAVRSIGIDFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>K9AZ60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WC-323|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GQGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A287AUY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKH
IRSEFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLK
ACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GQELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMLIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEQ
>A0A3D4YLX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYNKGVFINQCYDELNLRAPDLIRDVHKAYKKAGAEVLETNTFGANRIKLAQYGLE
AQVADINRAAAKIAREVADDDVLVAGAVGPLGVRLEPFGPTSLDEARAAFREQLQALKDG
GCDLFILETFADVHEIEQAILAAHEVDPTIPVIAQMTIGSDCHTPYGVSVEDIAQSLDAF
GADIIGLNCSVGPQIILDAIEKMVPVTRRKLSAQPNAGMPRDVSGRSMYMASPEYMATYA
HHLVQAGAKIVGGCCGTTPEHIAAMVEGVRPLSPRQPRVPARERRQAQPDVPPENPGVQP
VPLAERSKWGAKIARGDFVTSVEIVPPRGVDASKMLRDTAALRDAGVDAVNVPDGPRAQS
RMGALLTSVLIEQQVGIETVIHYCCRDRNLLGMLSDLLGAAAVGLRNLLLITGDPPKMGP
YPNATAVFDIDAIGLTNLVSQLNHGLDPGGNAIGAPTKFTIGVGVNPAALDPAHELKRFE
WKVEAGAEYAITQPVFDVQQLEKFLSTIEHTRIPIVAGIWPLVSLRNAEFLANEVPGVVV
PAKVIERMRAASAKSKEHGVAEGIAIAREMLERVKPHVQGVQVSAPFGKVELALEVFRDT
LAPAQARTA
>A0A2V7GYT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MSVTLKNLLADGKVHVLDGAMGTMLYAKGFFLNVCYDELNLKQPKLVQEVHEEYVRAGAE
ILETNTFGANPVKLGSYGLADDTEKINQAAAELARRASGGRASVIGAIGPLGVRIEPFGP
TSREEAFAYFRRQAQGLIAGGVDGFILETFSDVNEIHEALRAVRNLSDLPVIAQMTIGDD
GLTHYGTAPETFAKQLTDWGADAVGVNCSVGPAGVLEAVEKLVKATDLPISAVPNAGLPK
DVGDRKIYLASPEYMASYARRMIESGARIVGGCCGTTPEHIKKIRDYVASVVPRHQPVVV
SREAIAPPAGVEAVPLAERSRWGAKLAAGKLVTSVEIVPPRGVDPAPMLAQCRALKAGGV
DAVNVPDGPRAQSRMGVLPSAMLIQREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRN
ILIITGDPPKMGPYPEATAVFDIDSIGLTNLVYRLNHGLDPGNNPIGAPTKWVIGVGVNP
GAVDLDRELSRFAWKVDAGAEFAVTQPVFDPRQLEQFLKRVEQFKIPIVAGIWPLISLRN
AEFLANEVPGVSVPEPVLARMRQAQDKGKEAALAEGVKIAREMFEQVKGTVQGVQVSAPF
GKVEVALEVFG
>A0A7H9BMQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinibacter bivalviorum|TrEMBL
MPTSLHTKIAQRQSGILLYGITPPKANNTPEKMAEIAALQIERIAPLNVDGLVLYDIQDE
ADRTDATRPFPFMATLDPLVYSRDYLAPLDVPKINYRCVGKYSPEVFRADLMAMNDGVSV
FVGAASREQQVSLTVAQAYALRRETNPALLVGGVAIPERHLVKHDEHIRVAHKVTEGCSF
FVTQCVYNVEAAKNFLSDYYYACQASGTAMVPIIFTITPCGSVKTLEFMKWLGISIPKWL
ENDLVHSGDILANSLEACKGIFSELLQYANEKGIPVGCNVESVAIRKDEIEASLQLVRDV
QAMFAR
>A0A8D0YSN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGGDQWEAEEGGFSYAADLVKHIRS
EFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACS
EMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVS
LCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRP
IFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQE
LTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINS
QPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVK
GENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESP
SRMLIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>A0A7X3R6W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MNTSLLDHLRSSMLVADGASGTMLYARGVPMEVCFDEINLSRPDLIRKIHEEYVDAGAGL
IETNTFGANALSLSKYNLEDQAETLNARGVEIAREAAGSRAFVAGAVGPARGLPHWDYTE
ADHRRVHAEQIAALAGGGADAIILETFLRLDELKAALAVCQEICDLPTICQLAVDQYGQS
DDGFEVVEAFDQLRAAGADVVGVNCRSGPKGLLDALAPVPLSEGLMLSAFPNAGSPVYVD
GRFIYEATPEYFATSALRLRDQGVRLIGGCCGTLPEHVQAMARALEGREIVTRKKVLPVE
VRVPARPERIARPVPASPAVEPSIVDLVKERVTVIVELDPPRDLDHGPIVRGAQALKKAG
ADALTMADNSLAVTRISNMAVGQIVKEEAGIRPLLHITCRDRNLASLQSQVLGLHALGID
HVLAVTGDPVKFGDQPGASNVYDVSSFELIRLIKQMNDGVGFSGRTLNGRTAFTVAAAFD
PNGPNLDRRIRRLERKVEAGADMIMTQPLFDRRQAKQIYEATRDAGVPIFPGVMPLVSDG
NTEFLHNEVPGFVVPDDVRARMARVGRGRKARREGVAIARELIESVLANFNGLYLITPFN
RYPMTVELTEFALQATTRKAPG
>A0A2V7N9I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYGKGFFLNVCYDELNLKQPKLIQEVHEAYVRAGAELIETNTFGANPKKLASYGLA
DDTEKINTAAARLARAAAGDRVSVLGAVGPLGVRIEPFGPTSREEAFTFFRRQVDGLLTG
GVDGFILETFSDLDEIHAALRAVRSACDLPAITQMTIGTDGLTHYGTDPETFAKQLAEWG
ADVIGANCSVGPAGVLEAVERIVKATDRPISAVPNAGLPKDVGDRQIYLASPEYMASYAR
RMIEAGARFVGGCCGTTPEHIKKMRDYIASVVPRHPTVVISRSAVTTPAGVEAVPLAERS
GWGAKLACGEFVTSVEIVPPKGVDPTPMLEQCRALRAAGVAAVNVPDGPRAQSRMGVLPS
AILIQREVGIEPVIHYCCRDRNLLGMLSDILGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLTNLVYRLNHGLDPGSNPIGAPTRWVIGVGVNPGALDLDRELSRFAWKVDAGA
EFAVTQPVFDVRQLELFLERVEQFKIPVVAGIWPLLSLRNAEFLANEVPGVSVPEEVLAR
MRKVSDRGKEAALAEGVAIAREMFRQVKGAVQGVQVSAPFGRVEVALEVFK
>A0A239R4Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotellaceae bacterium MN60|TrEMBL
MSILKLDAARRFSFEVLPPLKGTGTEKLFADIDKLREFDPAYINITTHHSEFVYKELENG
QFERQRIRRRPGTVAIAAAIQQKYGIPVQPHVICSGATIQDIEYELLDLQFLGISDLLLL
RGDKAKEDSRFMPTPGGHAHTTDLIRQVARFNEGFFADGTPIKHPGQKFDYGVACYPEKH
EEAPNLEMDMQYLKEKQELGAQYAVTQLFFDNQKYFDFVKKAREMGITIPIIPGIKPLAK
LTQLTVVPKTFHCDIPEALAKEIVKCKTDEDAKQLGIEWTTAQCQELYANGINNIHFYTV
SAVDSVAEVAKRLL
>V9VZ99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leisingera methylohalidivorans DSM 14336|TrEMBL
MAGLEGACKTLVDLGYQPVPYVGARHLQNESQLREHLTAARSGGACRLLVLAGDRDGSLG
PYNDAMPVLAVPSISDLGSSHIPISGPPEGHPRIGGAQLVEALENKLEFLAARGIQAFIT
TQFGFDAGSYASWINMLRARGIVTPINIGITGVTSIPARIKYSVLCGVGPSLSALRKRSG
AMVGLLKGFQPAELIDELSQALVLNDRVPVKLHFFPFGGAKKTFDWVAAQLGKPT
>A0A1N6SL24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora avicenniae|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTSEGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRHVIGRLAGVGVRNMLAVR
GDPPGNPGGEWVRHPEGVLYAEELVQLIREAGDFSVGVAAFPYKHPRSPDVASDTEHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTRMATIERSVQLSGAPF
PPALAARFEKVADDPEAVRKLGIEQASEMCGRLLDQGVPGIHFITLNRSTATREVWQNLR
VQARA
>L9U5F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas titanicae BH1|TrEMBL
MSSHEHPLGISFEFFPPSTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTREVVR
AVGESGINTAPHLSCIGSEKAQLRDLLAQYREEGVESLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAITAF
GTDVVSRLCQRLLEGGAPGLHFYTLNQAAPVLRIVDNLAG
>G6B172|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella stercorea DSM 18206|TrEMBL
MVNKIRKDNKMNISDILTSGGGEKHFSFEVLPPLKGTGTERLFSTIEKFRDFDPAYINIT
THHSEFVYRELDNGQYERLRVRRRPGTVAIAAAIQNKFGVPVIPHIICSGATADAIEYEL
IDLQFLGIENVLLLRGDKARDDSQFVPTPGGHAHTTDLIEQVNRFNEGFFNDGTPIKNPG
KKFHYGVACYPEKHEEALNIDLDLKYLKMKQDMGADYAVTQLFYDNRKYFRFVEKARQMG
ITIPIVPGIKPLAKLSQLTVVPRVFRCDFPQELAVEALKCKTDDDARQLGIEWSTEQCRQ
LYKAGVNNIHFYTVSAVDSVREVARRLL
>A0A1W6VNV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus thermodenitrificans|TrEMBL
MGLLDELKQRVLIADGAMGTLLYSHGIDRCFEELNLSKPEEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPSINRAAVRLAKQAANGRTHVLGTIGGLRTLNKSAVPLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLTIARKETTLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLQSLEEVPLPTRAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIEAMARALQDRKPVTKKTVKRRAVSVS
VQADNPSAVTPLPELARTRRSVIVELDPPKQLGIDKFLVGAKALHDAGIDALTLADNSLA
TPRISNVAVGSIVKEQLGVRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLISQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVER
MEKKIQYGAHYFLTQPVYSEEKIVEVYEATKHLHTPIYIGIMPLVSARNADFLHHEVPGI
TLSDEIRARMAACGNDPVEATREGIAIAKALIDAAFDLFNGIYLITPFLRYDMTVELIRY
IHEKEAAAKERKVVHG
>A0A1V4I2W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrobacter vulgaris|TrEMBL
MTDASAAVHNDLGAQKRPTISFEFFPPKTEEMEHNLWGTITRLAPLDPSFVSVTYGAGGS
TRERTHSTIARILSETQLRPAAHLTCVGAPRGEVDEIVSRYRDIGVRHIVALRGDPPGGI
GTAYSTHPEGYRSSTDLVAGIKRRHGDIEISVSAYPEKHPESPDIDTDIDVLKAKVDAGA
TRAITQVFFDNDLYLRYLDRVRARGIDIPIVPGIMPMHNFKQARAFVTKAGTTVPTWLAE
KFEGLDEDPETRKLIAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAICHLLGIRPDAA
QKAA
>A0A7K1TYQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga tropicalis|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYEHLDPLMAFKPAFINVTYHRSEHMFKKR
ADGTFEKVEIRKRPGTVAICAAVMNHYNVDAVPHLICGGFSREETENALIDLNYLGVDNV
LVLRGDAAKNESFFEPDPHGHRYADELLQQVVNMNNGLYLEEDLQSGVKTKFCIGVAGYP
EKHFEAPNMQTDMSYLKRKVENGADYIVTQMFFDNQKYFDFVAKCREMGITVPIIPGLKP
ITSRKQLTVLPRTFHVDIPTEFSNEILKCKTDKEVEAVGTEWLIKQSRELKAFGVPVLHY
YTLGKPNVICKAIEAL
>A0A7X6SSS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MSNIESTDSRFFSLEYFPPREQAGRERLIETTKKLIEIDPAYISVTYGAGGSTRSGTVET
IDMVKTLGCEAVPHLACIGSQPEEIIELLDFYKAKGVRKIVALRGDLPSGMGLSDSPLRY
AADLVRLIKEHAGDWFEISVAAYPEMHPQASSFEDDINHFVEKVQAGADTAITQYFYNAD
AYWDFVNRVEAKGVSIPIIAGIMPMTNYTQLARFSKMCGAEIPRWITVRLESYGDDLESI
RAFGHEVVTKICDELRSNGAPGIHFYTLNQAEPVLKIWRELTAK
>A0A7C6JH28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MSDKAVISAEFFPPRDIAAQEKLVRSAKSLMGLDLSYVSVTFGAGGSTRSGTVGAVDLLQ
NLGFDVAPHLSCIGSTKAEIAEILDGYQAKGIKRLVALRGDLPSGMGGDVGELRYASDLV
AFIREHSGDAFRVEVAAYPEMHPQALSFQEDLEHFVFKVKQGADAAITQYFYNANAYFDF
VDRVQKMGVDVPIIPGIMPIMNSSQLIRFSNMCGAEIPRWIKLRLADFGDDRASIRAFGL
DVVTKLSQDLIDGGAPGLHFYTLNGSETTMKIVERLSR
>A0A7V9VHW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexia bacterium|TrEMBL
MAHPFATELLKRPLLFDGAMGTMLYEAGRSLDECLDALNLSHPDIVSAVYRAYINAGADV
IETNTFGANRIRLGQHGFADKVRDIAFRGVKLAREEREISGKSVMIAGSIGPTGRTIAPI
GTLTAQHARDAFTEQIEALLEAGVDLLVMETMGSLDEMAAALDAAGACTDLPIVSLMTFA
EDGRTLSGHDPREVVATLAERNVAAIGANCSVGPQRLLRVIDHMHAATRDLDDPPALAAI
PNAGWPTIIGSRLIYRSSPEYFATFATDAISRGARIVGGCCGTTSEHIAAMRVAIDTSEP
TANGRGNTHSAGVHIRPVAPRQPIDVESDAPTSIKQMLGKKFLRCVEIDPPKGFNPQKAL
DGARLLKDAGVDAINVADSPMARVRMSAMTLCYLIQHEVDVETIIHFTTRDRSLMGLQSE
LLGAHAANVRNILALTGDPPNLGDYPESTAVYDVDSIGLIRIISRLNQGEDSFGASIGRG
ASFTIACAIDPTRQDLEEEARRLHDKIESGADFVMTQPIFDIDVWTRFLKIYGEAKLPVP
VMIGVLPLQSSRHAEFLHNEVPGITLTDKARDRMRQAGSSGRQEGVQMAQELLRELVPFA
DGTYLMPSFGRYEVAAEVISVLDEEPTISR
>A0A7V3NEP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MTCKKVILADGALGTYLYKKGIPLNKNFSLLNLEAPELIKSIHLEYIIAGANLIETNTFS
GNLYKIQDEEICYKVNLEGARIAKEVAKNKAIVAGSIGPIGKLLYPFSEIKREDIKKYFF
PQIEGLVDGNVDLIAVETQILIEEAEEIIKIIKRIKKDMPILLSFSFNEDRRTPFGVSVK
DVVELAEKYKVEFVGANCGVGPLSLSEIIDEFLSLTKLPVSSMPNAGLPTYKKGGFFYPS
HPEHFSNYALKMVQQGVKIIGGCCGTEPRHIINIRQKLSEFMDIKKESKIFIKEKKEKKK
EVLKEENLFKEKIKKGEFIFSLEVYPPKGILNEKVFENLKYLKEKGIEFANVVDLPLAKM
RMSGIAFSHIIKEKIGFEPILHFTCRDRNILSIYADLLGARALGIKNILALTGDPPIIGD
YPHATATYDLTKIGLLRLIKYLNEGKDISGREIEINFDFFAGTSISFSEIEDEDKIKEKI
EFGAKFFFTQPVYETCFIEKFKEKFDFPIFAGILICKDMKMLEYFAKEVPDIEIPEKILI
SFERFQEDFLRFQEDFLIDLIKDLKGVSNGVYLISPGVKKEIIEKIIKEVR
>A0A533SRH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MMVLENPFLKLLESGKPILSDGAMGTMLHKRGIGFEVCFDELNLTNPAVVGDIHREYIEA
GANIIQTNTFGANRYKLEQHGLEDRLVEINAAGVELARRVVWASFKNVMIAGDVGPLGVR
LAPFGRVQPEQARQVFAEQITALANAGVDLVIVETMTDLYEVREAIAAVRQVAPYLPVIA
SMTFTRDDRTLLGDDPVKVARGMHAFGADVIGVNCSGGPNQLLRILKAMREAVPEGKFSV
MPNAGWPQQVSGRIMYPAEPEYFGEYALSLWNAGATVLGGCCGTTPEHIASMARVLDSAA
DRVDPEGEAAILADRDEPQPIHAQPTQFAQKLADGRFVVAVEMDPPRGLSTHKLLAGASL
LAEAGADVINVADSPMARMRMSPWAVCSLLQRKIGVETVLHFPTRGRNLLRVQGDLLAAH
ALEVRNVFVVMGDATAIGDYPTAMDNYDLVPSGLIKLIKQGFNAGVDHAGVDIGQPTSFF
AGCALNLNPGDAEQEIKNLRRKLRAGADFILTQPIYSPSVAHRFLSQVRSELGDAMRPVL
AG
>A0A7V1NPX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MMPINFKSGNKLKESLDTGTFVYTSELSPERGIDISKIWATYELLKDRITAFNITDNQGA
NMKMSSLAGVIYIKQFGGEPIFQQTCRDRNRMALESDLLGAAAFGVKNILTLTGDYISFG
DHKHAKAVYDIDSVNLIEIVKGLNSGVDMNGNKLDGCTDFYIGAAVNPESVPLEPQLIKF
EKKIDSGCNFFQTQAVFDTDKFGKFYDFYKKYKDIKIIAGIYILKSAKTARFMNKSIPGI
YINDRIINELENASEPLKKGIEIAAGVARRLKHMVHGIHIMAYGIEDKIPYFLDEFER
>A0A350LZH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKKSFREVLKEGRFIVTSEVGPPKGTNVDRMVQIIELLKDKVDALNVTDNQGSVMRYPSW
GGCFLIVEQGGEPILQVTCRDRNRLAIQQDLLFAHSRGIRNVLCLTGDSIDVGDHKEAKP
VFDLDSVQLINLVQSLNSGKDIGGNQLDSPTDFCIGACTTASAEPIEPHLIKLQQKIDAG
IQFIQTQAVYDLDQFKRFMNYLCKLNKDVKVLAGIVLLTGPRMAVFLNENVPGIFVPQPL
IDQLQVAPKGKALSVGIEIAGRTIREIKEEGLCDGVHIMAIEKEEVVPQILEVAGL
>A0A1F3NXL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium RIFCSPLOWO2_12_FULL_37_12|TrEMBL
MKVTEHLKNAASTLFTFEILPPLKGHGIQEIFDAIDLLMDFNPPFIDVTYHRQDFIYVEL
PDGKIEKRPHRKRPGTVGICAAIINRYKIDPVPHIICGGFTKQDTEDALMDLDYLGIDNV
LAIQGDKRRNDKSFEPEINGNNNASDLLQQVMEMNKGNYLDPDLVVKTPLKFCVGVACYP
EKHSEAPNLETDIHYLKLKQDLGAEYAVTQMFFDNKKYFNFLDKCRSAGITLPIIPGIKP
ITGIKQLTMLPRDFSIDIPEELTREVLKAKSPDAIRQVGEEWCTAQCKELIQHKVPCLHF
YTMGKAHPVKNIVGRL
>A0A2P9GWE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacter sp. SbD2|TrEMBL
MSATTPSKLESILAAGHFAVTSECGPPRSAEGTVVDEKARLVGPYVDVINVTDNQTAVVR
MSSLASCIRIKQLGFEPVLQMTTRDRNRIGLQSDLLGAGAFGINNVLCLTGDHQRFGDHP
NAANVFDLDSTQLIQTVRQMRDEGKLLSGYEMTVPPKMFIGAAENPFADPFEIRVLRLAK
KVAAGAQFIQTQCIYNMEKFKLWMQQIVERGLHEKVSILAGITPMKSIGMARYMKAKVPG
MDVPDEVIKRLQGVPKDKVAAEGINIAVEQIQELKECPGVRGFHVMAIEWEEKVPEIVER
AGLYPRPKVD
>A0A1I7LGF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. UNCCL125|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTEEMEKILWGSIERLAPLQPSFVSVTYGAGGSTR
ERTHNTVARMVRETGLKPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPAEGVGH
AYRPHPGGYASTAELVEGIKRIGDFKVSVSAYPEKHPEAASLDADIEALKAKVDAGADQA
ITQFFFENEVFLRYLEKVRAAGITIPIIPGILPVQNFKQAANFARRTGASVPYWLAARFE
GLEDDVETRRLVAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AAKAAA
>A0A1E8ULY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC073D05|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKDLFAHQPNFEVN
>A0A1F9NLT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium GWB2_56_26|TrEMBL
MDAAQEISSPAQKKFSLIAEMDPPKGVNLQGFVDTALQVRGRVDAVRVTDCEHAIMRMSP
IAPCLALQDKGYEPEMIITGRDRNRISFQADLLSAAALGIKKIVIKEGHDPAEGDQPVAR
TSGDLDLESMLQCVAALNSGRDLAGESLDGATDFQVGVAIELSDDVNLNRERAEYFKKLA
VYGVQSVTLGPSYDINIIEQFLPFAEETKIKLYTSVMFLKSVTMIRYLNNLPGVPSIPNE
FLKKMMQAPVKKDAGMQVAADLCKELAPMGDGIVLLAIGLKDKLPEFLDIIGR
>A0A4Q5NU68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MLYGTTPPRVGATPEEVHLAAEKLVDRTKNLNLDGLIVYDVQDESERTGEPRPFPFLPTL
DSRVYSQLLYQLSQKAVITYKSATHMNEADWQQWLDQSQRDFGIATLSLVGSPTRRQKGD
TISLPRATEMARVHPANFMLGGVAIAERNSETRSESQRMIQKTQAGCEFFVSQSVYNSQK
TITLLNNYARECREAGLKPKRFILTFAPCGRAKTLEFIKWLGVSVPSEIERGILEAADPL
SESIGICRSILSEILGSLEDRSVPLGLNIESVSNKKEEIEASVELFKVLEKELKA
>A0A533SKA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MRIAEHILPGKQFLSLEFFPPKNSSDWPAFFRVVANLKNLQPLFVSVTYGAGGSTSDNTL
AIVTRLKREFSLEPMAHLTCVGATEQSILSFLENLATAGVDNVLALRGDPPQDPAFVLPE
SKDFIFASDLVSFIKEHYPAMGVGVAGYPEGHPESASLDKDLQSLKYKVDQGGDFIVTQL
FFDNDYYWDFVQRARELGIEKPIVPGIMPIFSLKVIQKVVSLCGATVPADFLKELEEAEE
QGGADAVLALGIRHARNQIMGLLKGGAPGVHLYTLNRDDACLELLEGIF
>A0A1J4SD43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desantisbacteria bacterium CG1_02_38_46|TrEMBL
MGALKNALKEGKFVVTGEVGPPKGTDITKLMEEAEIIKNRVVAINVTDIQSAVMRLGSMA
VCHLLKEKGTEPVFQMVCRDRNRLALQSDLLSASVLGIENVLCLTGDYTTLGDHPQTKPV
FDLDSVQLLAAAKGLCEGRDMAGQEIEGSPNFFLGAVVTPGADPIEPQILKMEKKIKAGA
QFFQTQAVYEVDKFAAFMEKVRRLGVPVMAGIVVLKGAKMAEFMNKNVAGVHVPDEIIDE
LKTSTDRVKTTIEISARLIKELKPLCQGVHIMPLGWGHHIPAILDAAGL
>A0A1P8UZD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger abyssi|TrEMBL
MKRPEISFEFFPPRNIEATFRLWDTVQALAPLDPRFVSVTYGAGGTTRELTRDVVATLHK
HSGLNVAAHLTCVDATKEETLAIVEQFRASGVTDIVALRGDPPKGATGFTPHPDGFGSSV
ELIEALRETGDFNIRVGAYPDVHPDAVSAQADIEFLKRKFDAGATEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGILPIENWKGARRFAENCGTKIPAWVIEAFDRAERDGRQDLLAT
AICTELCSELIEGGVDKLHFYTLNRPELTRDVCFALGVAPDVKLEHVA
>A0A1J5DHQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG2_30_43_15|TrEMBL
MHFQELLDSKKFLVISELQPPKGTDLTEFYDYAEKMRGRIDAVNVPDLQSAVMRLGSLSA
SYLLKEKGFTTICNMTCRDRNRLALQSDLLNISVLGIENIVLSRGEEPSLGDHPDTKPVF
DLTPLELISAIRDLQKGYDMAKSDLHGTPKFCVGSTVNSSAQRGALDLEIKKMEEEIRAG
VDFFLTTSVFELNIFENFIRKIEYLKVPIIPGIMILKSVGMARFMNKHVEDVFVPEVLIE
RLMKSADKPKTSVEIASELINGLKPLCQGVHLIPFGWEDKVPSIIEKAGLY
>A0A2I3HTC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nomascus leucogenys|TrEMBL
MDHRKARVLPTGHYCPSLGIWASQVVSVRSSVPHSISRNPAMVNEARGNSSLNPCLEGSA
SSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISS
SLQPLPPGSSDSPASASQIAGITDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDICVA
VSGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIV
PGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASG
LVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKS
YIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFE
VFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPS
SDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNAPGFPQSTRPF
GENITNAPELQPNPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIERWGKLYEEE
SPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNERETEAP
>A0A497L535|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MVAKRPAYSNLVKEIRSGKFVLTGELEPEKTTGLEEILASARAMKPYVVAANVTDNPLSM
AFMNSLVPSYIVQREIGLETVYQVTVRDRNRNALISDILAAAHLGIRNVLALSGDHTVLG
DNKGAMPVYDLDSAQFVYLLSKMIDEGVDLAGNEIHGKVEMNVGIAANPNADPLEPEVLK
IGRKVGLGVDFIQTQTMFDIDLVKEFLREIERFNCPTLVGIFPLKSFGIADFFDKYIPGV
HVPKELLEGMRRCKDEPDKEKRKALYDQVNIDFFEPFIKEIRKTTKAAGIHVMAVFYERI
FEPLLRTTM
>A0A2A2AWE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vandammella animalimorsus|TrEMBL
MSASAPSQPQAPRAALSLEFFPPKTEAGALKLRATRQALYPLQPQFCSVTYGAGGSTQAG
TFAAVREILAEGQQAAAHFSCIGATREKLRAELAELQAMGVKRLVALRGDLPSGYGLGGE
FQYASDLVAFIRTETGEHFHIEVAAYPEMHPQAASPEKDLQAFATKVHAGANSAITQYFF
NADAYFRFVDEAQRLGLDLPIVPGIMPIHAASQLLRFSDACGAEVPRWVRSRLQAYGDDT
ASIQAFGLDVVTQLCQRLLAAGAPGLHFYTMNQSTLVLEIARRLGLPTH
>A0A3N0BPL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter jejuensis|TrEMBL
MKITDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFEPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADNSFVPTKGGHCYATDLIEHIKNHNEGKFLHEDIETFKSDFCIGVAGYP
EKHFEAPNLNTDFKFLKKKVEMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLSQLNVLPKIFHIDLPEPLCDALSHAKNNNEAKEIGTEAMIKQCKELMDFGVPVLHF
YTMGRPEQTKQIAKAIF
>A0A7W6CFB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sediminicola|TrEMBL
MVAISQIHPNWERAPDGITDGFSLEITAKDVESLRAAAPAIPPETPIAVTFLPGEEAPAR
IAAAKAVRALGFEPMPHFSARRITSEAEFEDYLNTVVQEAGVRRCFVIAGDPDHAAGPYN
DSSELIATGLFEKAGIKAIGVGGHPEGHPNMTEEQCWEVLARKCVEIDARGMAPLVVTQF
GFDPDAALEWLAALRQRGIVAPVRIGVPGPAGIKTLMRFAARCGVGASASVLAKYGISIT
QLLGSAGPDKLVDALAKGLNESHGPVRLHFYPFGGLEKTVAWINSYRKSRG
>A0A7C3YIC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MREAYSELMKAISAGKFVYTGELEPVKTTSLKEVLEGARTLKGHVVAVNVTDNPTAFAYM
NALIPSYMIQREVGVEAVYQMTVRDRNRIALLSDILAAGALGIRNILALSGDHTTVGDTP
QARPVYDLDSTTFVYMLSKIVDEGVDLNGNRITEPPKFNVGIAANINADPLEPEVLKLER
KVKLGVDFIQTQAVYDVERAKRFMEAVDYLNTPVLIGLAPFRSVGMLDWMVKFVPGIAVP
EEVQERIRKADKKGGKTAVLEENVEIFGDLARELKKTTRARGLHLMAIGFEHIVPKIIER
AG
>A0A7C4CLP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MFISLEITPPKRDVEKVVNIVKQVRDSVDAVNITDTPLGQPRIPGFIFAIILRERLGVEP
IVHYKTINMNLTNLKSVLYGCVATGVKKFLFMRGDNPIEGSPISDISPEELSMWAKKELN
VETGLAVSWPISMDKLISKLSARPDYVFTQIFLSIEDAKRFRSMFDEAANKVGWFPPVYC
THLVFCEENLSTLKEVARLMGLEMPSFKLDVETNVNFITELERFFEGFMISSPGGYDHAI
QLIKTLKEA
>A0A850QPP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Undibacterium oligocarboniphilum|TrEMBL
MITHNFSIEFFPPKTEEGAEKLRVTRAKLGELKPKYFSVTFGAGGTTQQGTLDTVIEIRR
EGYDAAPHLSCVGGTRESIRQILQQYQAHDIRRLVALRGDLPSGYGMGGEFRHASDLVEF
IRAETGDWFHIEVAAYPEMHPQARSPQDDLNHFVRKMQAGANAAITQYFYNADAYFRFAD
EARKAGVSAPIVAGIMPITNSNQLQRFSEMCGAEIPRWIRLKLNSYGDDSASIKAFGLDV
VTQMCERLLQGGAPGLHFYSLNQAAATTAIWQRLL
>A0A7V8SKD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus laudensis|TrEMBL
MKITDIYREKNLQKKSVISLEVFPPKTDAGIETIYQTVAGLTHKPDYISVTYGAMGSLGR
ENKTLEIAEKIKKEYGIETMHHLTSINNNPEQITEILAEIKAKNVQNILALRGDLPKNTD
VTGCPDIYHYAHELITDIKKTGDFDIAAAIYPEGHVDSPLDVENIEHVKRKYDAGANFFI
SQLFFDNDKFLRLNDYVKNSGIEAPIAAGIMPVLQESQVARMLYFGASLPTRLIKIINKY
KDSPEDLQKAGMDYACKQIDDLLARGVDGVHIYTMNKPFVANTMMDRYL
>A0A351RIZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKYTGTAGILYDRLKSEILVADGAFGTYYAKKYDTGSLPELANLQASDRVLSIHKEYIEA
GAKIIRTNTFASNTVCLGAGFDEVRNNIKNAVDIAREAVKGTDVLVAADIGPIPGENMIE
KEHIEKEYVDIVNVFKECGVDIFVFETFPELGFIDKAIENAGENGFVITQFAINQFGYSS
AGFSARKLIEEAGKNSYIDACGFNCGVGPGHMKKLVQSLINRNDKYFAVLPNAGYPQVVS
GRMVFDDNNAAYFSQIMHDLAEDGADIIGGCCGTTPEYIRQMVLKIADVVHMKNASIEEE
ISEKKTANDVSFYKGKEGRKLIAVELAPPLGIDDEKIMDAAFLMKESGVDVLTFPDSPSG
RTRADSILMAEKVSRETGMCVMPHICCRDKNAIAMRSQLLGAHINDINNFLVITGDPIPS
VVRASVKSVFNFDSVGLMNIISDMNQEQFAGEPVIYGGAINQGRVNFKVELERVKKKMEA
GATFFMTQPVFSDEDIDRLRQIKEQTGARILCGIMPFVSLRNATFMKNEMTGINVTDEIL
SRYRADMSKEEGEETGIQIAREIIAKTTDFVDGYYFSFPFNRVHMLKKIIGKNNQ
>A0A497MVL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MVEERIFSNLMRELKAGKFVFTGELEPGKEGSIETTIEAARKLLGQVTACNVTDNPQSFG
CVNSLAAAFMVQKETGMECICQLRCSDKNRLALLSDVLAAGLLGIKNILAITGDYVSLGD
TPDVKPVYDLDSTLLTRMIRMIVDEGKDFRGNEIRNPPKLHVGVAANPGSEFLDMEVYKL
KRKVKAGAEFVQTQVVFLPEVVDRFFAKVKEVGGIDIPILIGIFPAKSYAEAKFFHEQVS
GVIVPEDYMAKLKETKEIKDKEKRKERIDQINIEYFTGFLEHLKSTPAAGCHIMAVGYPE
IIPELRKVVA
>A0A842R7Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MVTMTTKAYSNLKRALNEGKFVFTGELEPKFSTTIDDVIADANAMKEYVIAANVTDNPAS
DTGFLSVVASHLTQEATGLEMIWQLRCTDKNRMALMADLLTAPKLGLKNVLALTGDHPWC
SPDWRQSKPVYDLDSCTLIRLVNEMVEQGTAFGKEYSGDRIELNVGGAANPNAGPLEAEI
LKLKRKAKAGCDWFQTQVVYDIDETLAFLKEVNTKTKVPTLIGLFPMKSYRVAKGFDMMV
PGVEVPKDLLGKFKAVRKEWKNVDKQRMKEEFLKLNVEFLGPFIKELHEKRASAGIHIMA
VHYPEAFAPLLEYIK
>A0A6G4ANF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rhizosphaericus|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSRAELRNIIGQYAGAGIRNMLALR
GDPPGDPLGEWVQHPDGLTYAADLVQLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATKLCARLMAEEIPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A397RQ72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeroplasma bactoclasticum|TrEMBL
MKIDEILKKKRTLSFEVFPPKKGSLGIEKIFKTIDELKALNPDYISVTYGAGGSNRNSNV
EIASYIKNQAKIEALAHLTGGPSSYSDIDEIVKKLHSEGIENILALRGDKPIDFNDDYCK
TFKHATDLMEYLKDEDFTLAGACYPEGHNECESLYEDLAHMKEKEQAGAKFFVTQVFYDN
EYYYRLVSEARKAGIKSPIIPGIMPLVSHKSIPSIKNMCGASIPLDFRNMLEVYKDDPEL
LEEFGINYAVYQIEDLIAKGAPGIHLYIMNRASIAKKIYERLENVFSKLFWYISYCIFLF
GI
>A0A350VXI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKIRDIINGEKPTLSFEVFPPKKDTDFANVEAAAFGIAGLSPSYMSVTYGAGGSTKGHTI
ALAQAIQEKYNVPTIAHLTCVCANREGIKEALSELKSAGIENILALRGDIPKNYEGEVFT
DFSHASELVKLIKETGDFCVGGACYPEVHPDSANRKEDVLGLKRKVDAGCEYLTTQMFFD
NNIFFNFMYRLREAGITVPIIPGIMPITRKGQVKNAVKLSGCNVPERFKNIVDRFGDSEE
AMKQAGIAYATDQIIDLMANGVKNIHVYSMNKPEIAEGIQRNLSEILKA
>A0A1X8WMZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Canicola|TrEMBL
MNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEVEHRP
EEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESA
>A0A554XEW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidimonas charontis|TrEMBL
MAVPLSFEFFPPKTPEGADKLRAVRQRLYAARPQFCSVTYGAGGSTQEGTFATVAEILAE
GVPAAAHFSCIGATRARVRAQLAELQAMGVRRLVALRGDLPSGYGLGGEFTYASDLVAFI
RAEFDRAFHIEVAAYPEMHPQARSPQADLQAFATKVRAGADSAITQYFFNSDAYFRFVDE
AEALGVDIPIVPGIMPITNASQLMRFSDACGAEIPRWIRLRLQSFGDDVASIRAFGLDVV
TDLCDQLRTAGAPGLHFYTMNQADAVLTILQRLDLMPLS
>A0A1Q7P2X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenarchaeota archaeon 13_1_40CM_2_52_14|TrEMBL
MRLSDRARHHNLVTVELIPDRVVASDLALLRGRVDAITIPALRNGHNDPSYPKSFSITPQ
RRSLASASIINRAGITAVPSLTCRDCNRSDLSAIANQMAQGLGNVLIVYGDPYPQPHPGT
YEFTKTNELIREISSLNHGNDPCIGAVTNQHADNRENEISRTISRVDAGADFIVTNVAFD
SESVLEHRDALLGAGLGVPLFIQVSIPLSLNNVLFVSQKFDIPVPAHIRKKLSDDPSGGS
LAVAAEAYEALRGEANGIHFSYLFRQRNPIPTYRHLLETIGIAGPPLAPLAASALKTYPV
A
>A0A7W6RBG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseospira visakhapatnamensis|TrEMBL
MTIDSQTLARMTRDLPLSSPLPTDVSVSFEFFPPKTEAMAETLWQAVRRLEPLRPSFVSV
TYGAGGSTRERTHETVARIQGETSLDAAAHLTCVDATRDEVDAVARRYWEAGIRHIVALR
GDPPESDGVYRPTPGGYAFAADLVTGLRDVADFEISVAAYPESHPEAASAEADLDNLKRK
VDAGATRAITQFFFDTAVFARFRDRAAAAGITVPIVPGILPVTNFKTVARFAGACGATIP
PWMASVFEGLDQNGDTRQLVAAMVAAEQVRTLAAAGVDTFHFYTLNRAELATALCHILGV
RPAAPDGVPSPGA
>A0A840A8F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseococcus suduntuyensis|TrEMBL
MDTAPPNTLERWLTGPRVGTLPAPAAMPAPKLSFEFFPPKNEKLEADLWACIRRLEPLGP
RFVSVTYGAGGSTRSRTHDTVARLARETSLTPAAHLTCVGATQDEVNEVAREYLAAGVRH
IVALRGDPPTGASRYEPHPGGYAQAEDLVRGLRRIGDFDISVGAYPETHPAALNADADLD
FLKRKIDAGANRAITQYFFDTDIYLRFLDRCHAAGITVPIVPGIMPVTNFASVKRFSAMC
GASVPDWLGKLFEGLDEDESTRRMVAATVAAEQVRILQANGVDEFHFYTLNRPDLTYAIA
HILGARPAGVTAAA
>A0A7C3UUI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MKLTDLFRTGRFVVTGEVAPPKGTDVSGMLAEAGLLEGWVDAVNVTDNQSAVMRLSSLAA
AAKLAQAGITPVYQLTCRDRNRLALQSDLLAAAVLGIENVLLLTGDFVSKGDHPDAKPVY
DLDSVQLIDCARRLVEGRDMAGGALSGAPGFCFGAVVSPGTEPAEGQVIKLAKKVQAGAS
FVQTQAVYDAAELSAFLALVKDYGIQVPLMAGIVMLKSAAMARYMNDNVPGVRVPDDLIR
ELEATPKPQLEEV
>A0A6G9Q1U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus hilgardii|TrEMBL
MSLTALFNDKTVFSLEVFPPKKDSPKEAILPTLQQLQSINPDFISVTLGAGGSDHYTGTV
SIADLIQNQLNIPAVAHVPGLYQTESQVLNLLDHLSEINVKNILALRGDKIPGKEPVGVF
NHANELVSFVHKNRPDFSIASACYPDCHAEANGFVDDIAHLKEKVDAGADHLISQLFFDN
QSFYDFKEKTEIAGINVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQDSKQA
MKDAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWDATKSVFEAANQKKTEKASNH
>A0A7T2LLK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingosinicella flava|TrEMBL
MSPAAPAFAHNGKPLFEDVQGDIQVSFEFFPPKTEKMEETLWESVKTLEPLGPRFVSVTY
GAGGSTRARTHATVERIAKETRLAAAAHLTCVEASRAEIEEIARDYWAAGVRHIVALRGD
APEAGKAFQPHPDGYANAADLVAGLKAIAPFEISVAAYPECHPDSADKSADLDNLKRKID
AGADRAITQFFFSPECFFRFRDDAAAAGIAAEIVPGILPVSNVAQTRKFAGMCGASIPIW
MDRLFEGLDNLPAARQLVAATVAAELCGQLYAGGVRHFHFYTLNRAELSYAICHLLGLRP
AEFAA
>A0A5B8SHA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. CBA3102|TrEMBL
MSSETETSGTPRVPFSFELYPPRSASSEEALHDTVRRLAAAGPDFLSVTYGAGGSTGGRS
LDVLRFIRTQTDVEPLAHLTCVGNSYAGAATLIREFLDAGILSFLALRGDPPTGQTDDDL
GDLESAAQLVQLIDRVQAERAPYEEAPVPGLPGAARVDPRRKVNIAVAAFPKGHPRATHR
TQDVEALLAKQAAGATFAITQLFFHPDDYLAFVERARSAGVTIPILPGIMPITSPARLTR
VLELTGEDLPSELAIALDVEPTAEGRREIGIEWAARLAREVVAGGAPGVHLYAFNQHETV
LTVLAEAGILPALRH
>A0A1M4SQH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalibacter saccharofermentans DSM 14828|TrEMBL
MKTSALFKQKRVLSFEVFPPKQSGSVESFYSTVEELKDLAPDFISVTSGAGGSENNTETL
EIASTIKNKYGIESVVHLPGINLDKKEALKVLDDLKNAGIENILALRGDENPTFTPKNDF
KHASDLISFIEDNGDFNIIAACYPENHLECPTAIEDIHNLKYKVDAGTNQLITQLFFDNS
YFYDFRERAAIAGIDVPIEAGIMPVVNKRQIERMVSLCGVDLPKKFLSIINTFENNPEAL
LEAGIAYAVDQIVDLTANGVDGIHLYTMNNPYITRRIYESISTLLTS
>A0A3D4T2K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium nuruki|TrEMBL
MTSVPGAPSMQVPVTDTLKWGTPGRVPFSVEFMPPRDDAAEQRLWNAAEAYHDLGASFVS
VTYGAGGSSRTRTERVAARLATKPLTTLLHLTLVQHTEEELRGILREFASLGLTNLLALR
GDPPGDINGEWTAEPGGLSHAVELIELVRSMPECEQFEIGIASFPEGHPHAASLEDDTRY
TIDKLRAGAAYSITQIFFDVDSYLRLRDRLAAADPVHGAKPIIAELMPITSLRSLERQQE
LSGGTLPSSVVEPLLTAAAGDGEKNAAAVRRAGIEVTSAMAERLIAEGVPGIHFVTMNNV
RATQEVLHNLGMAPAWGPELGQDMVR
>V2UJ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter indicus CIP 110367|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDKDIQHFVEKVNAGANAALTQFFFNPDAYFYFV
ERIQQAGVNIPVAPGIMPITNASNLIRFADSTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVLKFCERLIAGGAPSLHFYTMNNTEPTRQLVTDLGLA
>A0A2V1BX57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cadophora sp. DSE1049|TrEMBL
MEKITTKIASLPPGSSYFSLEFFPPKTTMGSSNLRARLDRMSRALRPLFITVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRKLVDQALEDAKALGIRNILALRGDPPRGEE
YRDADEKRNGEGEGEGEEEEEFEWAVDLVRYIRKQYGDYFCIGVAAYPEGHADESDPAGQ
SLEHDLPYLVGKVQAGADFIMTQLFFDVEAYDKFEKRLREHESGAFKDMPIIPGMMPIQS
YQMIKRTTKLSHARMPPDVMARLDGVRGDDEMVKKVGVDIVSEIVTHFQKEPAPGPRGFH
FYTLNLEKAVAFILERTNLIPSSPLDSESAILDVPSPLESLQVNGSSHKRPSRRQSSIGS
DPHNRVIISGSKASNPDRETTAEEAAIPAEPVNTRANTLAISEGEGSLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVNQAIKLWGFPTSVEDITSLFIRHIEGSISALPWSEE
GLNEETNTIKSQLLKLNQKGWWTVASQPAVNGVKSSDPIFGWGPKNGFVFQKAFVELFIP
EADWKQLHAKLTSPEIAPTVSWYASNASGSFLSSSPNSSENGEDGGGSTNAVTWGAFPGK
EIITPTIIEEVSFRAWAEEAFGIWGEWGRVYPARSVSKGVVDGCREGYWLVNVIHHGYVE
REGLWELLLS
>R6XGH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. CAG:435|TrEMBL
MKQYPSLEIVPPLKGMTKDELLNDIRPFIEFNPKYINVTCHRDEVTYEEQPDGSYRKRLI
RRRVSETAVCGAIQSEFKVNVVPHLICGGLTAEQIEFQLQDFKFMGISNILALRGDCLTG
EKRFSPVPGGYDHANELVGAIRRFEKENGCEGFFRIGVGGYPEKHFEAANMDEDIANLKR
KVDAGADYITTQMFFDNQVFYKFVDRCRAAGISVPIIPGLKPISTPKQVRLLPESFSIDI
PFELTSEISAHENDRQAVYQIGQEWATAQCKDLLAHGVPGVHFYTMGKSANIIGILRECF
>A0A2A3YEA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium alimentarium|TrEMBL
MPAERAPSADDENAPRPWSRDPQFEVLPLPGISDLAGAHLPAGARVTVTASPAQGLSATV
TTAGELAGRGFTVIPHLAARMVPDERTADRIVERLGSAGVREVFVIGGDAPQPAGSFSDA
LDLLRVLPTDPALTIGIGAHPEGQPFLDDESADRLLRTKAEHASYMVTQMCFDATALLDW
VRRIRAQGIVLPVRPGIAAPVGAVRLARLGARIGVGRSLRLLTSSSTGVRRMMGPRTWQP
DELLDQLAPAYGDPELGLAGPHVYTFNALATVQDWWPTEAPHPPSAG
>A0A5S3PU76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter algarum|TrEMBL
MKVTEHIEAAKGKTLFSFEIIPPVKGRNIQELYDNIDPLMEYNPPFIDVTTSREEYVYID
RSGLLDKKLTRMRPGTVGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIENV
MALRGDAMREEKYFEPTKGGHPFAINLVEQIQNLNCGKYLHEVIETDDCADFCIGVAGYP
EKHLEAPSLKSDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVDAAKDAGINVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVDDCENNKSVRQVGIEWAIQQSKELKEAGVPVLHY
YSMGKSDNIQAIAKSLF
>A0A7Y2EWE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ilumatobacter sp|TrEMBL
MAVNPETFPTPPVRYRPRLLTTGRRPLVGSDTPHLRSLIEHATLELVPMKSLDRAVSELL
PARSISMTCSPARTIEDTLDETAKLVADGHTVAPHISARMVQSAAHLSEIVDRVHEIGTR
EVFVVGGDADPPGCFFDAIEFLDAFLDLDPNVDHIGFPAYPDSHPIIPSEALHAALHTKQ
AMILESGRTAHVSTQMCFSADQIRQWLLAEREAGLTIPVHLGIPGVIDKAKLMTMGVRLG
VGTSLRYLSKNRKAIGKMMTQRAFQPDQLLRPLASELLELGIGGLHLYTFNQVATTEAWR
QRILA
>A0A2N2MEV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-6|TrEMBL
MPIFTPGRRWQPAFSPFKHESFAHQVLATAELAIKGPLFGCRMCGNCMLQDTAFICPMEC
PKGLRNGPCGGSTANGCYVDETRPCIWYKIYERSFKMDREERLLEVLPPLDWEKAGTETW
GDVINQVRQVGPKKVVSGLAQAETRQETWESVFKPVRQPDWWQGDDRYHAPAYEEPVSEL
ERRLKAGEFVVTAEVAPPMTVKTDKMCKNIELVHESVAAVNFTDSPSATPRMSSWACSAL
AVQHGVEPVMQIAARDRTRVGLQGEVLGASALGIRNILCLSGDSMRLSGKPRGRMDVFDL
DAVQMLWILRRMRDEGRYLDGRELKTRPQFFLGAAAAPYASEPKFQALREQKKVNAGAQF
FQTNLVFDTERLDDWLNELGKRGILDKVYILVGITPLKSFKMARFMHDEVPGVVIPQSLL
TRMEQAEAAGNAAEEGVQIALELIENIKGKPGVNGLHLMAVGWEEIVPRIVAEAGLR
>A0A6B0DM60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax citrulli|TrEMBL
MSLSTHEAALPVSFEFFPPKTPEGADKLRTVRQQLYAHRPEFCSVTYGAGGSTQEGTFGT
VREILSEGVQAASHFSCIGATREGVRTQLAQLKAMGVSRLVALRGDLPSGYGAGGEFQYA
SDLVAFIRAEAGDDFHIEVAAYPEVHPQARSPEADLQAFATKVRAGAHSAITQYFFNPDA
YWRFVDDVRALGLDVPVIPGIMPIMGSTQLMRFSDACGAEIPRWIRLRLLGFGDDSASIR
AFGLDVVTALCERLRAGGAPSLHFYTMNQSAATLEICRRLGL
>A0A7C2ZNJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurella acetivorans|TrEMBL
MSIASLIAKKKLLTIEFNPPKNTDIQKHILKLEPFKNIVDAINVTDSPMAKPRMNSIVSA
NFIKDISEPIFNLTCRDKNKIAIQSDLLAASALGLKNILAITGDPAKDNDSVYKINVFEL
IKLIKNLNEQFNTGFFIGCASDIPKTNNISSIESRLKRKSEIGAEFVITQPIFSKNDLER
FLEASNNIKIHKIIGIMPIVSYQSALYLNNNVKGINIPKFILSKFENASIEDFKLITFEL
HNKLLNDIKNLLPYIDGLHIMKLDYEIAQLTKKFLEV
>A0A091BQ25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenimonas malthae CC-JY-1|TrEMBL
MTQLSFEFYPPKNDEQRAQLDRTVRKLKAHQPEFVSVTFGAGGSTLSYTPETVRGLRQEH
GLDGVPHLSCMGGTRAELRELLNLYRALGCNRIVALRGDLPSGMARAGDFRFAADLVAFI
RAEHGDHFRIEVGCYPEFHPQAEDALADLRHFKAKVDAGADSAITQYFFNADAYFRFVDE
VRAAGVSIPVIPGIMPISNFSQLRRFSEACGAEIPRWMAKRMQAFGDDAESIREFAADAV
AAMCRRLLEGGAPELHFYTLNLARPTEAVLSRLR
>A0A1J5I2C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium CG2_30_49_12|TrEMBL
MTNTGSNIERILDTGGFVVTSECGPPRGADAGVVRKKGELLRGVVDAVNVTDNQTSVVRM
SSLSACVILKEMGFDPILQMVCRDRNRIALQSDLLGAAALGINNVLCLSGDHQKFGDHPQ
AKNVFDIDSIQLIQAVRRMRDEGKFIGGEEIKGKPVLFIGAAANPFADPFEIRAPRLGKK
VKAGCEFIQTQCIYNLERFERWMAMVRDRGLHEKCAILAGVTPFKSVGMAKYMKNQVPGM
DVPDEMIERMKGVPKEKQTEEGIKICVETIQRLREIPGVRGIHIMAIEWEDRVSEIAKAA
GLLPRPQLP
>A0A3D5F4B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPG
>A0A1Q9Y241|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. PA15(2017)|TrEMBL
MSQKRPNVSFEFFPTKTDAGHEKLLNTARELAGYSPDFFSCTYGAGGSTRDRTLNTVLQL
DSEVKVPTAPHLSCVGDSKAELIELLNLYKSKGIKRIVALRGDLPSGMGMSSGELRHAND
LVELIRTETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADCYF
YFVERVRKLGVDIPVIPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDTQSIQRF
GEEMITGLCERLIEGGAPGLHFYTLNQAAPSLAVWKNLQG
>A0A523R7F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Cloacimonetes bacterium|TrEMBL
MELAKYLERNYVIADGAMGTTLYRKGFSSKKPFATLNIENPGLVMEIHTEFVEAGAELLV
TNTFDANIFKLDPYVGFKEIKIVNRKGAELAKKVSGERRWVAGSIGPSGKTFSLLEEDEK
EWFKESLIEQVEGLVEGGVDALLVETQIGTNEARFILETIEKCRKSVPIILAFTFTEGLR
TPSGETVEEIIEAAKDFSLLAIGANHGIGPLQFLELMPHFLEKSTIPVSFMPNSGVPRYI
DGTFVFPASSEHFARYAREFIKKGVKLVGGCCGTTPTYIELLVTMLKSKTGKSLHFLFVE
EEEIETQEVAVKERIENIVEEQIDAKSLVVVEVSPPRGVNVKKSIEWIEKIKEFGVDAVS
ILDSPMARVRMNPVAFSYLVRERGLEAIPHFALRDRSLTRIQSDLIAACALGLNNIFAIS
GDPPSLGDYPQSTAVYDITSPGLIKLIKLLNKGKDFAGNVYTNPTYFYVGAAVNPSPPDI
KKEMAKIEEKIDAGTDYFVTQPLFDSKTLRGFIEKVDLKNTPVVLNIFIPKSKKQFEYIA
NEVPGIQVPRELMNIVEEKENWLPFLQDELIKLLQELKPLISGLYIAVPRGKTAFLRPFM
EEIKGKKWGL
>A0A177MFS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas methanica|TrEMBL
MNISFEIVPRSLEAFDQQYGFVQTLDKGINIINVPDIQRFDTRSWELATRVDRRKYRFIP
HFRAIDFKIESGELYRIIEEYALDSVLLVSGDPPEGLKRSFYNTDVVDLIRAVRQRFPSL
HIYAGFDPHRSGVQDECDYIQRKVDAGAGGFFSQPFYDSRMIDIYAEHMQDLETYIGISP
ITSKASMNYWEVKNKVKFPKSFRPDYDWNVEFANGVIASAAANGLNVYFMPIRIDLARYF
GEIKLGG
>A0A4P8RKD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter sp. SGAir0037|TrEMBL
MKVTDHFKNAGDKTLFTFEILPPLKGENMKTLFDHIDPLMEFNPPFIDVTYHREEYVYKQ
RENGLLEKITTRKRPGTVGICAAIQNYYKVDTVPHLICGGFNKEETENALIDLHFLGIDN
VLVLRGDCVKSESRFVPEPGGHHYATQLIEQVVDMNNGRYLDDEQAYTNGTNFCIGVAGY
PEKHSEAPNLKADLRWLKKKIELGANYIVTQMFFDNQKYIDFVKLCREEGIDVPIIPGLK
PITTKNQLTVLPSVFHIDIPADLADAVEACADNKAAAQVGIEWAIKQSKELMEFGVPCLH
YYSMGRSGSVRKVAEALF
>A0A839YMV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limimaricola variabilis|TrEMBL
MSLLSFRRAKPAPSMGGDLTARASIEVMPRTAAKVASFAALLPAGTRVYIAHIDGTPIEE
MVATAARIAGEGFAVMPHFPARSIESEAQLGDWIARYQGEAGVTQALVLAGGIAAPRGAF
HSSMQLLETGAFDRAGFTRLHVAGHPEGNLDIDPDGGDALVRDALRWKQDFSNRTDARMA
LVTQFVFDAAPVIGWARAIRTAGIDLPVHVGLAGPAKLQTLIKYAMACGVGPSLKVLQKR
AMDVSHLLMPYAPDEIADALEKAVLAEPELGIEQAHLFPLGGIQASADWLAARHPARHSA
AL
>A0A218UA53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lonchura striata domestica|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCHQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEEDGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIISQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLNSPTQQ
>A0A6N9RHK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp|TrEMBL
MNIPVSFEFFPPKTPEGVDKLRLTRQALYACQPEFCSVTFGAGGSTQEGTFSTVKAILDE
GVAAASHFSCVGATRATVREQLATLRAMGVKRLVALRGDLPSGYGAGGEFHYASDLVAFI
RRETGDAFHLEVAAYPEIHPQAKSAEADLQAFVAKVRAGADSAITQYFFNADAYFRFVDD
VQRLGAEVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIRSFGLDVM
TGLCDQLRTAGVPGIHFYTMNQAAATSEIIRRLKPA
>A0A1H2RDG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoreibacter albidus|TrEMBL
MTRPNVSFEFFPPKSVEASFRLWDTIQTLAPLEPTFVSVTYGAGGTTRELTHEAVTALHK
TTDLRVAAHLTCVDATRDETLSIARDYIKAGVTDIVALRGDAPKGQDFSVSEGGFASSIE
LIEALKTETDATIRVGAYPDSHPEAGSMADNIAYLKRKFDAGADAAITQFFFEADTFFRF
RDACVKAGIDQPILPGIFPIEDWTRARNFAIRTGTKVPAWLDEAFTAAIRDDRHDLLAQS
VVTELCSDLVDGGVEDLHFYTLNRPELTRDICAALGITPKSALAQVA
>J8MCF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VD166|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0G4NCV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium longisporum|TrEMBL
MHIKEMLADAERDGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIA
ELTCEMVTQAQSVYGLETCMHLTCTDMGLDKVNDALRKAYKAGCTNILALRGDPPREKEK
WVAADGGFEYARDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEESLLDHLKEKTCMHLTC
TDMGLEKVNDALRKAYKAGCTNILALRGDPPREKEKWVAADGGFEYARDLVKHIRATYHD
HFXHFLRARTRGLSGWALRAKAREVMGAVRTAADDETLLGKFKAWVVAEIAGEGEQQRQA
FTDAEIEGMLAEMEMEYGGEIGGGASLL
>A0A269PMN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. NBT06-2|TrEMBL
MALSLKQKIQDPKQGVYLIGTTPPKMGTDKAQLETIANKLLDRLHEIEYDGVIIYDIQDE
SSRTAVPRPFPFRKTVDPREYSQLISQLSELDVITYKSVAQRDEAEFNTWLDETAQEYKL
KNLVLVGSPSSTGDIKLSLPNAYKTLGSHKSNVFLGGVTIAERHASKRNEHERLLEKIDQ
GCEFFISQAVYNAQETIDLITSYSRSCRHNGISPKRIILTFTPCGGEKTLDFMKWLGISV
PEATKWRILDSNDSLNESIRICRDNLNQILQSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKATMELNLAEKQIA
>M3UH42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia malaquae NBRC 108250|TrEMBL
MSERNESTAVAARGQSVVERIAAPHSGPVPFSVEFFPPRDEAAEARLWRAVRVFERMNPA
FVSMTYGAGGTTRDRTVRIAGELATETTLLTIAHLTAVNHSIDELRALVGAYADKGIVNL
LALRGDPPGDPLGTWTKHPQGVEYASELVELIDSLGDFHTGVASFPEGHHRSPDLASDTE
NLVRKLRAGAEYSVTQVFFDVDDYFRLRDRVVAADPEQGAKPLIPGLMPITSLATARRMT
ELSGSTIPADVEKRLVEAAGDGPEEDKAAIRQVGIDLCTEMAQRLIDEGAPCLHFCSLNF
TKATSEVLERIGIDTRGALERASV
>R6LQA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:170|TrEMBL
MSVAEIYENRATFSFEVFPPKTDVGMEKLCGEGGVLEKLYTLNPDYISCTYGAGGTNVGK
NLEVLDKIQKDGKCTPVTHFTCIGNTKEDIKEKLQTYLDHGIDHMLALRGDLPFGWTGTN
GDLHYATELVKFVRKEFGDKFTIAVAGSPEGHIQCRSLEADIAFLKQKQDNGADFIISQL
CWDMDAFRYWFDAIRDAGIWMPVDVGIMPILDQAATINMALSRNGCVMDRKLCEIISKNW
IFPNPFEKEPFDADVEGKKASFKAAGIEYTINQIDEYRACGVDGIHLYALNKYDDVAYIA
KAAGLIDLV
>A0A1F9BTR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_58_19|TrEMBL
MSKLKEALESGAFAVVAELKPPKGVRVEGMLAPVAALKDRVTAFGVPDNEQARMRLSALA
GSRLAQEAGGEPLLHLTCRDRNRLALESELLGAAALGIENVLLVSGDYVTLGDHPDAKPV
YDADSVQLLKIARDLAEGRDSAGLALDGAPNFFLGAMVIPEAEPLAPQLLKFGKKVRAGA
HFFVTPAVFDLEKLRAFRQHLSATPIKLLATVKVLSPEEAAQADTEQRRQVYRVPPEFLQ
KLEGLEGEEFYRRAAELAGRLLKGIKAENLADGAYLKAGGRVDLITLVLKAAGL
>A0A1F8V5A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coxiella sp. RIFCSPHIGHO2_12_FULL_44_14|TrEMBL
MSREYPAERQKQGKQGISISFEFFPPNTREGLIKLSDICDALNRFRPQYFSVTFGAGGGN
RTKTFRTVRLLLSKNLRVAPHLTCVGLPKPVIRHMLKNYIRQGIRRIVALRGDLPETEVH
RGDFYYANELVDFIRTETGSHFHIDVAAHPEFHPQAINVFAGLENFKRKIAAGADRAITQ
YFFNPDAYFRFLDNCHQYGITVPIVPGIMPISHFEKLLRFSRLCGAEIPTWLFKRLEAYR
DDEVSLRAYGIDVVTRLCEDLLRGGAPGLHFYTLNQLSPTQHIINQLERCLVYC
>A0A1K1NY28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus flavefaciens|TrEMBL
MHIKELFGKKTVFSFEVFPPKKDSPVDIIYDTLDELQGLSPDFISVTFGAGGSGNSKHAL
EIASKIKDSGTIPMLHLPCINFTKAEIDAALSEAQQRGIENILALRGDINPDIPPVDDFH
HASDLITYIKSKGDFDIAGACYPECHPDAADMIEDIKNLKAKVDAGADHLISQLFFDNDS
FYAFREKAAIAGINVPIEAGIMPVVNKNQIERMVTTCGASLPAKFVRIMTKYEHSPEALR
DAGIAYAVNQIVDLVASGVDGIHLYTMNKPYVARKICEAVSGIIGA
>A0A5C6HM65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidaceae bacterium HV4-6-C5C|TrEMBL
MRIIDLINSNKKTAFSFEILPPLKGTGIEKLYETIDTLRDFDPKYINITTHRSEYVYKDL
GDGLFQRYKLRRRPGTVAVAAAIQNKYDITAVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHEAMFTPEGDGYYHATDLQEQINNFNKGIFIDGSEMKITETPFSYGVACYP
EKHEEAPNIDIDIYWLKKKMELGAEYAVTQLFYDNQQYFDFIKRIREAGITIPVIPGIKP
LKKKNQLNIVPKTFKVDIPEPLALEIAKCKDDKEVEQVGIEWCTQQCKELIAEGVPSIHF
YSIGAVNSIKEVAKAIY
>A0A512NQU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reyranella soli|TrEMBL
MSPDTGPLGGPYSVSTAEFPARAPQRLKVSFEFSPPKTEAAERTLWETVTRLVPLQPTFF
SVTYGAGGSTRQRTHETVARLKKETGVDAAAHLTCVGATQGEIDDIARAYWDAGIRHIVA
LRGDPPSGMGGKYSPHPGGYANAAELIAGLKKIGPFQISVAAYPEKHPDSPDDTADLENL
KRKVDAGADRCITQFFFEVDDFLRFRDRAAAMGVNAPIVPGIMPVSNFQSVARIAGLCGS
KVPPWFAGLFEGLDEDVETRRMIAATVAGDLCRRLRDEGVDQFHFYTLNRADLTFAICHL
LGVRPQ
>A0A2M7AA02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium CG07_land_8_20_14_0_80_59_28|TrEMBL
MSGCNLLDRLRTEIVLGDGGMGSMLHSLGVNIEESFDNLNLTHPDLVESVHRQYVAAGAE
LIETNTFSANRNQLGRAGLVESAREINLAGARLARQCASSNVYVAGSVGPLGKSLEADSQ
LRASEQAEAFREQIEALVEGNVDLILLETFSDLDEISIAFRAARELCDLPVICQMAFTNE
LHTLAGVSALDALRTLEMLGADVVGGNCGAGPNALVKVMENIAGETDLPLSAFPNASYPQ
YADGRYFFVGDPEYLADGAARLAETGANLIGGCCGTTPAHIRAMAQRLAYRFVRPRRKLV
SVAVAEQETVAPAEPQLPDFLQKVGREPVVIVELDPPRGLVWQPLVEGAKTLAQAGTDAI
SVAENSLASIRMSSMVMGHFIQRDAGIPAIVHITCRDRNLLGQQSELMGASELGIRYVLA
ITGDPVSMGGVLGATSVYDTNSFGLIEMLTQLNRGESVTGRSLGRRADFIVAGGFNPNVR
KLEGEVKRLSKKVERGATFALTQPVYDAAKVPEIYDQTSHLGIPIFLGVLPLYSARNCEF
LHNEVPGIRIPDGVRKRMVEASEGDAWKVGIEICAQFIGDVLNMVPGVYIVPPFGRHEMA
LPLVKLVKSGVPTGAVKGSPLR
>A0A6I3KVL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia aurantiaca|TrEMBL
MSFDNVRGYSTPGRVSRTPHVSGTRSVVQQLGPRPDGSIPFSVEFNPPRDAAGEARLWRA
AREFERLHPAFVSMTYGAGGSTRDRTIRVTGQLARETTLLTVAHLTAVDHSVAELRSIVG
AYADAGIRNLLVLRGDPPGDVLGEWIKHPEGVEYAEELVRMVRDLGDFHVGVASFPQGHP
RSTDLDQDTRFLVSKLRAGAEYSITQMFFDVEHYLRLRDRVIACDPIEGAKPIIPELMPV
TSLRTVQRAEELSGRPLPAKVMERLRKAAGNGPDEDRAAVRACGIEIATEMAQRLISEGA
PCLHFITLNFAKATSEVLANLGYTMSATPAHA
>A0A3N6GP43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ADI97-07|TrEMBL
MDCLSTTSVPAVAALLRDFSLEMTAKDIPGLEEARTHIPAGTRINVTFLGSEDLAMRLAA
ARAVQQSGFTPVPHISARRLRSRSELDQFLGALSSDGTAGSVFVIGGDPVTPHGPYGDSL
ALIRSGLPQKHGVRHVGIAGYPEGHPAIAGPALWSAVKDKTTALAQHGLSGDVITQFGFD
AEPVLTWVEEVRKRGIDVPVRVGVPGPAGVRRLMTYAARFGVGTSASLAKKYGFSVTQLM
GTAGPERFIRALADGYDERRHGVLKLHFYTFGGLGATSRWVSDFRTGEES
>A0A2U3ET47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. CGMCC 5087|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A3M1JPJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MPEGARVYIAALPNKPVDGQVEAASRLRGIGLEPVPHLVARSFASPEDLDRLLGQLVEGA
AIERALVLGGDRDDPAGNMTSALDIIRTGLLEDHGIRRISIGCYPEGHPRISDEELRRAL
HEKLEAADKAGLETILVSQFCFDPNAILNFVRDLRADGINTPIRIGVAGPAKAATLIKYA
MICGVGPSLRALKERQSLARNLLGAVTPEDILRDVAVAREREPELRIWGIHFFTFAALRK
SIEWAEERIDRSKDPDAVPDDVFAENSEKP
>A0A537NEF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MRAEPRASRFVHAADAPRIRVSFEFFPPKTEEMERTLWESITRLAPLRPNFVSVTYGAGG
STRERTHSTVKRILSDTGLAPAAHLTCVAATCEEIDTVIRDYCTAGVRHIVALRGDPIGG
LGDRYAPHPGGYRNAAHLVAGIKRLADVEVSVSAYPEKHPDSPTVAADLDMLAAKVDAGA
SRAITQFFFENDRYFAYLDRVRARGITVPIVPGILAVQNFKQTKTFAARCGASVPDWLAR
RFDGLDEDAATRKLIAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAVCHLLGLRPSAE
HAPPNGACGTSAANSCALPLPLGARLAAREAG
>A0A232M5M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elaphomyces granulatus|TrEMBL
MHIKQKLAVERESRRPGVSFEFFPPKTAQGVQNLYERMDRMHSLGPAFIDITWGAGGRLS
ELTCKMVSVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYDAGCTNILALRGDPPREREK
WEATKGGFRYAKDLVKYIRGKYGNHFDIGVGGYPEGCDDNPDVDLLIDHLKEKVDAGSSF
VITQMFYDVDNFLSWEQKCRDRGIDCPIIPGIMPIHTYAAFIRRSNWTKIRIPPGWLEAL
EPVKNDDAAVRKIGKDLVADMCKKLLQSGIYHLHFYTMNLAQSTRMIMEDLKLMPSEEMP
LQKPLPWRQSLGLRRRDEDVRPIFWRNRNESYIARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSLRGLSDIFIRYLQGDLDRLPWSDAPISAEADAIKSDLID
LNRRGFLTINSQPAVNGAKSSHPVYGWGPKNGYVYQKAYLELLIPPEFIDEILSRIEKNP
DLSYYCISKNGLLKTNSSDSPNAVTWGIFASKEVIQPTIVETISFLAWKDEAYRLGEDWA
KCHAQNSLSRRLIQDIMDGWYLVNIVNNDFHKTHDIFGLFKGLSVKNFGVEVTIVDGIES
NGHANVN
>A0A095SK11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax nanhaiticus|TrEMBL
MSKRISFEFFPPKTDEGKSKLLATQKKLLVKNPEFFSCTFGAGGSTRDNTRDMVNKLREQ
HGDTAPHLSCIGQSKEEILELVHGYKNAGVTRIVALRGDLPSGMGYAQSEIKYADELVAL
IRQETDDHFQLEVAAYPEMHPQARSFEDDIAHLKRKIDAGANSGLTQYFYNADAYGYYMD
ALRKIGCDAPVYPGIMPILNVANLLRFSNTCGADVPRWLQSKLNDIKDDDAAVKAFGEEV
VTRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGL
>A0A246RZF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas campaniensis|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIRVRDELAARKPRFFSVTYGAGGSTQARTRQVVR
EVSESGISTAPHLSCIGSEKAQLRDLLLQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLEGGAPGLHFYTLNQAAPVLKIVDNLTD
>A0A356X7Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneolaceae bacterium|TrEMBL
MKVNEHIKKANGNTLFSFEVLPPLKGQNIRSLFDHMDPLMEFNPPFVDVTYHREEFVYKK
RENGLLERKTVRKRPGTVGICAAIQNHYKVDAVPHIICGGFSREDTENALIDLNFLGIDN
VLLIQGDTRKPEREFVPEPDGHAHASDLLEQVVDLNNGIYLDEELENAKPSDFCIGVAGY
PEKHFAAPNMQTDLKYLKLKQDLGADYVVTQMFFENQHYFDFVKKCRDNDITLPIIPGLK
PITSPKQLTILPQLFYVDLPMELTKEVEKCNNRDEVRQVGIEWTIQQSKELMEFGVPSLH
FYSMGKSASVYEVAKELF
>D8JZ03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium denitrificans (strain ATCC 51888 / DSM 1869 / NCIMB 11706 / TK 0415)|TrEMBL
MAQGNERKSKLLGSGDIVVSFEFFPPKTEKMEETLWSSISRLAPLRPEFVSVTYGAGGST
RERTHATVTRLLRETDLKPAAHLTCVDASKEEVDAVARAYWDAGVRHIVALRGDPAQGAG
TKYEPHPGGYTNAADLVAGLKKIANFEISVAGYPETHPESPSVEADIENLKAKVDAGADR
IITQFGFDNAHFLRYLERARAAGIWVPISPGIVPIHNFKQVSGFAKRAGATVPSWLARRF
EGLEDDPATTHLVAAAAATEQVMDLVDEGIKKFHFYTLNRADLVYAICHLLGLRSARTDA
SANAA
>A0A0T2Q903|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altererythrobacter sp. Root672|TrEMBL
MSYASIHPDWEKPRRNMADGYSLEMTAKEIEGLREAAPLIRPGTQIAVTFLPGEEIEQRV
EAAVLVRELGFEPIVHLSARRILSEAQLDKYLEDITTKAGVKRVFIIAGDPPEAEGPYSD
SLQIIETGLLQKHGIQIVGIGGHPEGHPNNTPEQLWDWMERKIAAIRAGGMTPLVVTQFA
FDDDAIVEWVGEMRKRGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGISLTN
LIGSAGPDKLVNSLDTKLNDEEHGRVRLHFYPFGALTPSAEWINQYDAKH
>A0A2A5BQM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MDVSFEFFPPKTQKMEDALWGCIRSLEPLNPHMVSVTYGAGGSTRERTHATISRILKETD
LLPAAHLTCVGASRGEIDDIAQEYWDMGVRHIVALRGDMPTIGQAYAPHEQGYINAADLV
SGLKKIGDFHLSVAAYPESHPDSADSQADIDNLKRKIDSGADQVITQYFFDVDMYFRFMD
KVLAAGIDVPIIPGIMPVTNFAQAKNFSARCGTTMPKWLESLFDGLDGRPEIRRHVAATV
AAEQCMRLYQGGVKKFHFYTLNRSELTATICHFLGVRPKEEPEGENT
>C0CK19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia hydrogenotrophica (strain DSM 10507 / JCM 14656 / S5a33)|TrEMBL
MKITELFERGEFVVSAEVGPPKGIHIEHLLEEAKTYLSGITAVNVTDNQSSVMRLGSLAV
CKALKDEGLTPIFQMTCRDRNRIALQSDLLSAAMLGIENLLLLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVRKLEEGEDLGGNKLVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVRAGA
DYFQTQAVYEPEKFIKFMEKAKQFGKPVQLGIVIPKSAGMAKFMNDNVAGIHVPQEMLDE
LKKDKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAGL
>A0A537KZ71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MPKSLKGKIAAGAQFAQTQFCMDIEIVRRYVARLAEHGLTERIALLIGVAPLRSGRSARW
IKEQLYGAIIPDDIVERLEYAGDPAAEGRQICADFIEQLATVPGVAGAHIMAPNNEGMIP
GVITRARAVVTDRAKTRAVFGKVRHA
>A0A8G7P922|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus epidermidis|TrEMBL
MSHLLNQLKSNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKSFGLEHKVKEIHQAAVQIAKRAANEDTIILGTVGGFRGVRQEDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELTRIVTATRQKYDIPIIAQLTASNTNYLVDG
TEINAALKYVVECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDIAQELINEGVRLIGGCCGTTPEHIRYIKSAVKHLKPVKDKKVIPINKAS
SQKQTRVLKQNLTSKVKNGPTVIVELDTPKHLDTDTFFDNVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQHYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITRDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGINTDGDALKKHTNFNIAGAFDPNVRKLDGAIKR
LEKKVASGMSYFITQPVYSKEKIIQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSDDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A6B3HYJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8455|TrEMBL
TEKGERNLWNALRRIEAVRPSFVSVTYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVS
HSVAELRNMIGQYADAGIRNILAVRGDPPGDPLAEWVEHPQGVKYAADLVRLIKESGDFC
VGVAAFPEMHPRSSDWETDIGHFV
>A0A5B9D6M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Prometheoarchaeum syntrophicum|TrEMBL
MLIKEFFKQKKPVISFEVFPPTRNYNLDSIYSTIEALKALNPDFISVTYGAGGGTKDHTV
EIASIIKNKYKIESLAHLTCVSAKKQEIIQIAKELNENNIENVLALRGDLPSDPNFKFPT
PLHYKYASDLIEELNHRYNFCIGAAFYPEGHIEAENFETDLKYVKFKVETGACFLISQIF
FDNTYFYHFKDRFEEMGLKIPLSAGIMPVTNAKQMNRITTLCGSTIPRKLSKIIAKNHQN
PLKLQNEGIYYAAQQINDLIANGVDGIHIYTMNRPEIAKKILEKVNL
>A0A2S3UAD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum subsp. plantarum|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHADHPVYILGTIGGLAGDTDATVQR
ATPATIAASVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFVGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>M5RJ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula maiorica SM1|TrEMBL
MKNVARLKDFNPSFFTCTYGAGGSTRGTTLDVVEKVKEVTGLPVASHLTCVGSTVDQLED
YLSEAKNRGVDYIVALRGDPPKGSEQFEAVEGGLRYANELVELIRSRFSDFGILVAGYPE
VHQEATDAKTDLENLKRKVDAGADVVVTQLFYDNADFYRFRDDCVAAGITVPIVPGILPV
TNFKQALRIAAMCKAAIPSRLSDAMN
>A0A5Q4SCI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. wa22|TrEMBL
MALGTPSTRTDHARTVRELLATGETSFSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVRYAADLVRLIKEAGDFCVGVAAFPERHPRSADWDSDIGHFVD
KCRAGADYAITQMFFQPESYLQMRDRVVAAGCDTPVIPEVMPLTSVRQLERFAQLSNASL
PSALKDRILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A5C5CEN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella pecoris|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWDTVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVVREFAELGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPSWLAERFE
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTEATL
EVA
>G5HD18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] citroniae WAL-17108|TrEMBL
MKIRDILAQGRPTLSFEVFPPKTEDAYDTVERAAAKIATLKPDFMSVTYGAGGGTSDYTV
GIASDIQKSGVTPLAHLTCVSSTRDKVHSVLEELKNHGIENVLALRGDIPADGRTPREYH
YASELIHEIKQSGDFCIGAACYPEGHVESANKSVDMDYLKEKVEAGCDFVTTQMFFDNSI
LYSYLYRIREKGITVPVIAGIMPVTSAKQIKRITQMSGTYLPSRFLAIVDKFGDNPAAMK
QAGIAYATDQIIDLIANGVRGIHVYSMNKPDVAMKIRENLSEIL
>A0A5N5QST9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceratobasidium theobromae|TrEMBL
MKVTEKIQQAEKDNRVWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTNELVKTCQGVIGIETCMHLTCTNMHQEKIDTALREAKANGCRNILALRGDPPSGQEE
WTTVEGGFQHGVDLVRYIRQQYGDYFDIAVAGFPQTIQLPEAEAKQEMQWLKEKCDAGAN
FIFTQMFYDANMFIRWVKAAREAGITIPIVPGINPIQTWNGFIRATTLSKTKIPQDLMDV
LEPHKSNDEKVRELGTKIVADMCRKILDADIGIKGLHFYTMNLEKGTKMLLEELNLVPRI
ETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTPEEGLKIWGTPTTIEDIKSLFTRFCAKEVKALPWSDQPPSNEMLVIGQQLA
RMNELGYLTINSQPAVNGARSDDKAFGWGPKNGYVYQKAYLEFFVHPEQLQSLIKRIERD
PNVTYYAINKQGDLKTNSISDGPTAVTWGVFPGKEVIQPTIVEAVSFMAWKDEAFELGCQ
WAKIYEPGSPSRKLIESMMNEYFLVNVVHNDFNDREAIFRPFFADAGLKMNGDEMTTPVA
NGVNGVNGVNGVNGVKAINGLANGHLKAAMA
>A0A1I3ZNU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacillus dabanensis|TrEMBL
MDLREDLQNKTLIGDGAMGTLLYSYGIDRCFEELNLSHAEEVLNVHRAYVHAGADVIQTN
TYGANYIKLTRYGLQDHVKEINTAAVRLAKQASGGKRYVVGTIGGIRGVRKQAVSIEEIK
RSFREQLYCLLFEKVDGLLLETYYDLEEIRTVLEIARKETNLPIIAQVSMHEAGVLQDGT
SLPAALKQLEDLGADVVGVNCRLGPYHTIQSLEEVPLPETAVLSAYPNASLPAFQDGRLV
YPTDPTYFQKSAQSLYEQGARLIGGCCGTTPEHIEAIVARVKGKAPIKDKVVPFTKETEV
IAAAPKDTRPHLHEKAKKGRSIIVELDPPKKLKTERFLQGAEALREAGIDSLTLADNSLA
SPRICNTAIASIIKEKYDIDPLVHIACRDRNLLGLQSHLMGLHTLGIRQLLAITGDPTKI
GDFPGATSVYDLNSFDLIHYIKQMNKGISFSGKSLGESTSFSVAAAFNPNVRNLNRAVGR
MEKKIKYGADYFISQPVFNEEQMIEAYEATKHIEAPIYIGIMPLTSIRNAEFLHNEVPGI
TLAKEVLEKMELAGTDKTKAQAEGIRISKSLIDTALDLFNGIYLITPFLRYDITVELTKY
IKEQSAKRERKVSNGIRMV
>A0A7W8JSC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus humi|TrEMBL
MTRISIELVPRSRSGLRAELMAVAEHLPGADTINIPDFPRFTTRSWHGCAFARPRYRAIP
HIRAVDLNPRAPLEMAAHLHEHGIDEVIVITGDAPSDMNAKVYNVDAEAAIRRIRRELPH
LKVYAGLDPYRQSLAREQDYLERKLEAGACGFFTQPFFDLRLMDAYADLLPEGAEVWWGA
TSVTSEGSLGYWRTRNHAVFPRQFQPTMEWNRRFAADLLTFARERGQHAYFMPIKADVRE
YLGGIV
>A0A6P1FAJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. VKM Ac-2759|TrEMBL
MSTSRAESPPEPHCPSPVPFSFEIYPPRTADGTAALLGTVDRLAEAGPSFISVTYGAGGS
SRSSSLEILRHIHRSTPVEALAHLTCVGSTHAQASRLVHEFLEAGVTRFLALRGDPPAGT
AEGEEVPGDLGSAAELVQLIHRVQAEREPYGAVTMPGRPNAQRVDIASRPRAQVAVAAFP
NGHPRSRSLSQDIDALLAKEAAGASFAITQLFFHPSDYVRFVERARIAGVRMPIIPGVMP
VTSPGRLRRMLELSGEDLPAELAIALDVEPDDEGRRRIGVAHAAAMVRTLLEAGAPAIHL
YAFNRHEEPLAVLAESGLLPREPALAGDRNPSPPLTTERPS
>A0A849P443|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelistega suis|TrEMBL
MSRQNFFSLEFFPPRDEAARERLQQTTQELLAVEPDYFSVTFGAGGSTQDGTIETVRMLK
AQGLEAVPHLSCIGNKPEQILAIVEQFKQMGVKKIVTLRGDLPSGMGLMDNSLRYASDLV
ALIRQHYDDYFHLEVAAYPEMHPQAQSPSDDLAHFITKVKAGANSAITQYFYNADAYFDF
VERLQAKGVDIPVVAGIMPITNFSQLSRFSQMCGAEIPRWIRLRLAEFGDDRASIKAFGT
EVVTELCQKLIDHGVPGIHFYTLNQSAATLAIWRNLTI
>A0A0E3PQZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina siciliae C2J|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRYSVPLEDARHLKGLADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDFPSCGDHPGSKP
VYDLDSVQLIELVRKLDSGVDLAGNQLDGGTSFCAGAVSSIDPEKILQLIKLEKKVRGGA
DFIQTQAVYDVGVFEEFTEAVNHLEVPIIAGLIPLKSLGMAEYMNKNISGIHVPDEIMLR
MKEASSPLEEGLLIASETVKELTKLSRGVHIMPIGSHKNTPKLLSMAGISEI
>A0A509ELA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium symbioticum|TrEMBL
MPTASQHRASRDGYRPIRVSIEFFPPKTEEMEKILWNSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETKLRPAAHLTCVDATKEEIDGVVQSYWDAGVRHIVALRGDPAEGVG
HAYRPHPGGYAQTADLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFDNEIYLRYLDKVRAAGIEIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLEDDVETRRLVAAAVAAEQVLDLVDQGVEDFHFYSMNRSDLVYAICHLLGLRAQGPKV
AAQKAA
>A0A285BVQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas ureae|TrEMBL
MDSQKKFSPTFSFELFPPQTPQGIEKLRLTRQQLAQFNPKFFSVTFGAGGSTRERTFETV
LEIQSEKHVVAPHLSCIGSTQQNIRIILEKYYEIGIRRIVALRGDLPSGMAQAGEFRYAS
ELVAFIRKEFGSSFHIEVAAYPEYHPQARSAQADFENFKRKIETGANSAITQYFYNTEAY
FHFVDSCESAGLNIPIVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLEGYSDDSASIQA
FGLDVVTDLCERLLKAGAPGLHFYTLNSASLTSIIWQRLNLKEYVQ
>A0A496CAF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. OF01-14|TrEMBL
MKVIDLIRNSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQKPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNDKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A1M3EJ02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. 73-145|TrEMBL
MSVADARTAESGPVVAPVDRPTVSFELFPPRNPDAAPKLWDTIRRLEAVRPDFVSVTYGA
SGRTRTTSRALVRRMLHETTLTPIAHLTCVGASREEISTIVREFLDEGVRSFLALRGDPP
EGEARWQAHPHGLTTASQLVELLREIEQERCEQSPAQAVRARVKPLSIAVAAFPRGNRLT
GSSREQDIQALLAKQRAGADFAITQVFYDADSYLELVGEARRAGVVIPIVPGLIPATDPA
RLVRTEQVTGVPVPPDLLALLDEADDEAERRRRGLRFGIELIDRVLEGGAPGIHLYTFNK
HEAALDLLEGAGLVGRPTATTTARTDA
>A0A4Z0JMA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMTQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6D0EFL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLKAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A257FML0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium PBB2|TrEMBL
MSTATPRVPVSFEFFPPNTPVGTEKLKTVVQDLSVLNPHYFSVTYGAGGSTREKTLSTVM
DIAAAGYEAAPHLSCVGSTRENIAEILATYRAQNIRRVVALRGDLPSGTATAGEFRYASE
LVAFIRETQGPDWQIEVAAYPEYHPQQRYAAKDLQHFAAKMRAGANSAITQFFFNPDAYF
HFVDEVRKLGVDAPIVPGIMPFHNYARIAQFAARDGIEIPRWVALKMEGYMDDAASIREF
GLEVMTRVCERLIAGGATSIHFYTLNQSALTLALCKRLGLG
>A0A3L9HM94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYP
>A0A0P4UP20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. NIES-2104|TrEMBL
MKVSVSDFKLLALPDTLNQEVLHSRSLMTYPQFSNPLGHAPLSALRNAAKRGEFLVTAEV
APPKGTDPTHMLQMAHLLKGRVHGVNITDGSRAVMRMSSLVSAALLLQQGIEPIYQVACR
DRNAIGLQADLLGAHALGIRNVLALTGDPVKAGDHPESKPVFELESVRLLQMVSKLNGGN
DWNDKTLTDGETDLFVGAAVDPQCGSWSGLQKRFERKVNAGAQFFQSQLITDFDRLDKFM
TQIAGDCGKPVLAGIFLLKSAKNARFINRAVPGVNIPEHIIDRLEKADDPLKEGMLIAAE
QVKLAKDLCQGVHMMAVKREDLIPEILDLAGIPSIDRTLAEVGKA
>A0A6S6UCI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Thiotrichaceae bacterium|TrEMBL
MNAPVSQLAAKQKTNNTPELSFEFFPAKTPRMERNLWRTMGQLELLNPGYFSMTYGALGS
ERDHSLNMVSSMLKEGHVPVAAHLTSAGHTRDSLIELVQHFHNEGVQRIVALRGDADMVE
GGITDVAVMVEELLGVADFDISVAAYPEVHPKAKSLQADLAHLKRKLDAGAQRALTQYFF
DADVFLRFRDEAEKAGITQQLVPGILPIHDFAKVTSFSSRCGANVPEFMHDLFAGTEAGS
AEQKQIGIDHATKLGETLLAEGVDALHFYTLNMPNLSFEVARNLGVSKGDVSVSKAA
>A0A3R9IX75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MRLLRQALNDQSFVCIMEFVPKPSAQRFAALESIMARAQLCGWPLAVSIADRVGSALDMS
PLDACRSFDTPVPTLLHFSGKDRERQDLLAQLPRMDAAGLDQLLLLTGDRLPGHMPGQRP
VRYLESVAALQIVRQARPDWLLGAALNPFKYREEEGGAQYFKAEKKLAAGVDFFILQLGF
DFQKYREAMHWMQRQPTPRPLLACIMGLTDGRAGMLEHVAGVTVSPAMRALLAAEAAVSK
AHARQRATERLALQIIGLRLLGYAGINLSGVHELEQFLELEQALEDWLPRINSLEQWRSA
WDAAWQMPDVAPVTFHPPGYHWQQGQRQVQASFTEKARYHLLSAMHHQLFSRETLLSQAF
GWSVRRALWSTPAAARVLHGVERSLKRPLVGCDTCGQCRLEDTLYICPETCPKGLANGPC
GGTQLNRCEFGDRECIHSRKYRTAVSVGQTHVLSEKLIPCVEVSGRQQSSWPRWFAEPTP
VQPAARAKRPQPEIADL
>A0A379KIE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKSALREKTFVCVMEFVPKPSAERFAAMEAIMARGHLCGWPMTVAIGDRVGSPLDLS
PLDALSSFSKPVPALPHFSGKDRERHDLLAQLKRMDAAGLDQLLLLTGDRLPGHQPGERP
VRYLESVAALQLARKACPHWLLGAALNPFKYREEEGGAQYFKAEKKLAAGADFLTLQLGF
DASKHLEAMQWMGRQAEPKPLLACLMSLSHGRAAMLEHVAGVTVSPSMRDMLEAEAGVSK
AYAQARGLDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEDWQARVHSQEQWTTA
WAGSWQMPGLPAVTFHPPQADWRQGQSRVSATAREKLRYHLLHGFHALLFSRNNWLSKTF
GWAVRQPLWASDSGARWLHGLERIVKRPLLGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVQQTAVLTERLIPCIEVQTRHRSSWPQWFAVQTP
ARFSPQPTLRNPPESSPQAVHRQ
>A0A6I6XCP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKAALREKHFVCVMEFVPKPSAERFAAMEAIMARGQLCGWPMTVAIGDRVGSPLDMS
PLDALGSFSTPLPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGERP
VRYLESVAALLIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DASKHQEAIHWMQRQASPKPMLACLMSLTHGRATMLEHVAGVTVSPSMRDLLEAESKVSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGIHELKQLLALEARLEHWQAQIHSLEHWAPA
WADSWQMPGLPIVAFHPPQGNWHQGESTVSASGKEKLRYHLLHGAHSLLFSRTNWLSKAF
GWTVRQPLWATKRGARVLHGLERAVKRPLIGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFEAQPP
RQLSPQPAPRTQPES
>A0A7U6RE40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSTERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DGDKHQEAMHWMRRQATPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETVQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQARIHTLDQWAPA
WRASWQMPGLPAVTFHPPQAGWRQGESRVDASLKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQRLWSTPVGAQVLHKVERAVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFQAATP
RRLSPQPAPRSQPES
>A0A8I1JJZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A4D6X9W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MNLLKTALHDRTFVCVMEFVPKPSAERFAAMQAIMDRKQLCGWPLTVAIGDRVASALDLS
PLDALDSFATPLPALPHFSGKDRERHHLLAQLRRMQAAGQEQLLILTGDRLPGHQPGERP
VRYLESVAALQIARQACPNLLLGAALNPFKYREEEGGAQYFKAEKKLAAGADFLTLQLGF
DARKHHEALLWMQRQAQPKPLLACLMSLTHGRAAMLEHVAGVTVTPSMLDMLEAEAAESK
AYAQARSVDRLALQIIGVKLMGYAGVHLSGIHALEQLLALETRLEHWQSRLHTLEQWAPE
WAASWQMPGLPAVTFHPPQGSWRLGETRSRASFKEKARYHLLHGAHSLLFSRENWLSKTF
GWAVRQPLWASPAGARVLHRLERSAKRPVVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTTLNRCEFGDRECIHSVKYRTAMAVEQTAVLTQRLIPCISAESRHQSSWPAWFDAAQP
QFGAPLSPEPMLRQEASVNAESSSPCKTRSSKAFAEAQR
>Q3B375|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium luteolum (strain DSM 273 / BCRC 81028 / 2530)|TrEMBL
MLVKEILNTAEKPVFSFEFFPPKKDEDWETLFDTIKALSPLNPSYVSVTYGAGGSTRTRT
HDLVTRIQKETGLSVVSHLTCIASSREETGIILENYRRHGINNVLALRGDKPAGAATLAE
AIKDFPHAIDLVGFIKSNYPDFGVGVAGFPEGHPETPNRLTEIEYLKEKVDAGADYIVTQ
LFFDNRDFFDFRDRCRLAGITVPIIAGIMPVTTKKGMIRMSELALGARIPAPLQEKVMAA
SSEGEVASIGIEWATCQVQELVDNHVRGIHFYTLNMADATLRIFRNLHA
>A0A2M8Q323|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phototrophicales bacterium|TrEMBL
MTKPPFLERIAQRPLLADGAMGTMLHQLGVKHGISYDALNLSDPHLVGTVHRRYIEAGAE
LIETNTFSANAIKLKEYGLEHEVVTINEAGVDIAKQAIAQTNRSDIYIGGSVGPLGIHLA
PLGRLKREEAKRIFHAQIATLIHAGVDVILLETFTNLAEIQLAIEVSKSINPDIPVIASM
TFTRDDRTLLGETPITVAHTLAASDADVIGVNCSGGPAQLRRILKRIRQTEPHKPLIVMP
NAGWPENINGRLAYPSTPEYFAEYAIVFETTGACIIGGCCGTTPEHIAAMRQALNDQNLP
HEIETIEVITPEEEQSLEALPPTELAQKLVNREFVVTVEMAPPRGCAPEKVLAAAEMLHQ
AGATNINVSDSPMARMRMSPWALAYLIQERIGIETVLHFPTRGRNLLRVQGDLLAAHALG
VRNIFVVMGDPTHIGDYPDAFNNHDIVPSGLIRLIKKNFNEGIDQAGNAMNERTGFLVGT
ALNLNRPEMEKEVDLLHKKIEAGADFALTQPIYDPRAAERFIQQYETQYGTLTLPIIVGL
LPLYSIKHASFLHNEVPGIDIPEHVLARVANAEKPAAEGVKIAQELTLALKDIVNGIYLM
PPFAKYYLAADVIDILAIPTT
>K0NL76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula toluolica (strain DSM 7467 / Tol2)|TrEMBL
MTLQNKLSQGDFVVLAEINTPKGVDISDLVTNVRHLKSRIDAVVIPGMDNGVMHMSALAG
GAIIRQQGMEPMIHIYGRDRNRMALQGDMLAAHILGVNNLLVVQGEAISHGDHQNAKPVD
DLNELELLIMLNTLQRGTDLAGFELKGKPEFFTGCQVQPIRNDDHLEIEFQSAGEKVEAG
AQYIMVPPVFDIDGYVQILNKFKSLNVPVIATVYMLKNVGMARYISINDPASKLSEATIT
RIRKSKDRETECINIAGEMIKELQSQVQGVKISASGWEDRLPAILDCAGL
>A0A0B4EUC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium anisopliae (strain ARSEF 549)|TrEMBL
MHIKDMLAEAEKGGQPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLDKVNAALQKAYKAGCTNILALRGDPPRAQEK
WTAAEGGFHYARDLVKHIRATYGDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGKVRERGINIPILPGIMPIATYASFLRRAKHMQCKVPDHWMTAL
EPVKNDDVAVREIGKTLVAEMCRKLLANGIYHLHFYTMNLAQATRMVLEELTWAPCAERP
LQQALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTTVQDIASIFVKYLNREIESLPWSEAPLTGEANAIKDNLIQ
LNKRGLLTINSQPAVDGVKSSHPIHGWGPSNGYVYQKAYLELLVPASIFTEMVKRVEDKP
TLTYYAVTKDGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGTDW
AHCFESETPSRVLLDQIMNEWYLVNVVNNDFHENQTIFDLFERLEVKGLDTPVAV
>A0A3B8XZD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanothece sp. UBA12306|TrEMBL
MINHFRQAAQNKEFLITAEVTPPKGGNPRRMIEMAKQLKGRVHGVNVTDGSRAVLRMSSM
AASALLLQYGIEPICQFACRDRNAIGIQADLMGAYALGLRNVLALTGDPVKAGDHPKSKA
VFELESVRLLKVIDNLNRGVDFNNKSLPDEPLDLFAGAAVDPQSPSWSGLKSRFEKKLAS
GAQFFQSQLITDFDRLDKFMHQIASQTDKPILAGIFLLKSAKNARFINKKVPGVNIPDTI
INRLADAEDPLQEGVKIAAEQVQIAQQLCQGVHMMAVKREDLIPQILDLAGVKPIFNQ
>U4T251|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter aquaticus CMS 56|TrEMBL
MSKPAFSFEFFPAKTEQGHDKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVHALCA
RGDTDIAPHMSCIGDDKSEIAELLDLYKGLGIKRLVALRGDLPSGQVGMGELPFAVDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFAFDVDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTVAKPLVAGIMPITNSSNLIRFADSCGADIPRYVRKQLSDFGDDSKAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVEALGLTA
>A0A374W9H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. OM05-12|TrEMBL
MKVIDLIRSNEKTAFSFEILPPLKGTGIEKLYNTIDTLREFDPKYINITTHRSEYVYKDL
ENGLFEKRKMRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHEAAFTPEGNGYHHAIELQQQINDFNKGLFVDGSPIKVTGTPFSYGVACYP
EKHEEAPNIESDIHWLKKKVEAGAEYAVTQLFYDNRKYFDFVKRVREEGINVPIIPGIKP
FAKISQLSMVPKTFKVDLPEPLAQEAAKCKTDEEAKQVGIEWCIQQCKELMAHGVPSIHF
YTVSAIESIKQIAKEIY
>A0A0P7DI44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITGMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLQLPR
>A0A1F9WTE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFOXYA2_FULL_50_26|TrEMBL
MNTFKRKLDDNKFVITVELLPPKGTDVSALMEKARMLQGAVDAINVTDNQRASMRLGSLA
VCRLLKERGHETVLQMTCRDRNRIALQSDLLSASALGIENILILSGDHPRNSENRGAKPV
YDLDTVQLISAARLLEQGVDMAGKKLEGKPCFNIGAVVNPASDNADLQIMMMEKKASAGA
VFFQTQPVFDIDQYSIFAGRIKHIPAKIIPGVALLKSASFVNFLRSIPGITIPDEVARRV
EAAPDQLKEGIAICAETIRELKKISHGVHIMAIGMEAHIPEILSRID
>E0RRB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaeta thermophila (strain ATCC 49972 / DSM 6192 / RI 19.B1)|TrEMBL
MVRDLFRQGRTLFSFEFFPPKTSSGWESLFATVRELALLEPDFMSVTYGAGGSSREKTHE
LVVRIRQELGVEVVAHLTCVGSTEEEIVRILEAYDREGIHNILALRGDIPPSLAHHPNPF
GVFPHAVDLVRFIKARFPHMCVGAAAFPEGHPETPNRLKEMEHLKHKVDAGVDFLVTQLF
FDNRDYYDFCERCELAGIRVPVIAGIMPITTRKNMERMAELAAGMHYPARLLRALSRVTD
DEGFFHVGVHWAAEQIRDLLDHRVPGIHLYTLNTSRAVKAICETLGIHHLPQLG
>A0A109CR56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Magnetominusculus xianensis|TrEMBL
MSFKEAIESGKFVVTAEVGPPKGTDIATMIHDMHILKGKIDAVNVTDNQSAVMRICSLAV
CKIAMEQGLEPILQMTCRDRNRIALQSDLLGASVLGIHNVLCMTGDHVTAGDQKGAKSVY
DIESVQLLQLVDSLNKGKDMHGNDLKGTTSFFQGAVVTPEANPLEPQLMKFEKKVRAGAN
FFQTQAIYDIEKFKSFMTFAKKTGAKIMAGLVVLKSVGMANFLNNNVPGIKVPPELIAEL
KAAGKEKALDTGLSITARHIKQLKEENICDGVHIMAIGMEDKVPEILQRAGLL
>A0A264Y4Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. 885|TrEMBL
MSVTEILNSQDGAKHFSFEVLPPLKGAGTDRLFSTIEKFRDFDPAYINITTHHSEYVYRE
LDNGQFERLRVRRRPGTVAIAATIQKNFGIPVIPHIICSGATAEDIEYELIDMQFLEIEN
LLLLRGDKAKEDRMYTATPGGHTHTTDLIQQVNDFNRGFFVDGTQMKHPGQPFSFGVACY
PEKHEEAPNLEMDIQYLKMKQDMGAEYAVTQLFYDNAKYFDFVEKCREAGVTMPLIPGIK
PFAKLSQLTVVPKTFHCDLPLELAEEVVKCKTDEDAKQLGIEWSTEQCRQLYRAGIRNIH
FYTVSAVDSVREVAKRLL
>A0A2N1YCV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium HGW-Gammaproteobacteria-15|TrEMBL
MAFANAQYLDAINRNLQDVEGKVNVSFEFFPPKTPQMEQTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASKEALIDIARDYWQNGIRHIVALRGD
LPPGSIAKPDLYAADLVEILRSVADFDISVAAYPEVHPEAPNAQFDLLNLKRKVEAGASR
AITQFFFDTEKFLRYRDRCAAIGIDVDIVPGILPVTNFQQLKKFADLTNVAVPAWMHKAY
EGLENDVTTRNLVAANIAMEMVKVLSREGVDHFHFYTLNRSELSYAICHLLGVRPQAAG
>A0A2N1RRA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetae bacterium HGW-Spirochaetae-5|TrEMBL
MHIREIIDNHKISFSFEFFPPKTEKSSEALFQNIIELVNLKPAYVSVTYGAGGSTRDLTH
DLIVKIQNQTNLTVVSHLTCVGSTVEEIHSILTRYSENRIENIMALRGDPPAGSNRFIKT
EGGFEYASELVEYVKKHFPSMGIGVAGYPEGHPETPNRIKEMDNLKRKVDAGADYICTQL
FFDNNDFYDFCERCDIAGIKIPIIAGIMPVTSIKGMNRMAELALGTKIPAKLQRAIARAE
DDSYVERVGIHWATQQVHELIDNNVKGIHFYTLNQSRATRDIYTSLGISNSMSLNR
>A0A369RSN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoplax sp. H2|TrEMBL
MLHYTTVAVTVDDNAFILSTISKDYLSVVSLKMTTEKVNDKYIGTEYKSMDCQYGAKKSV
ITDGIVDDNYDDAHIIQKIRKRINSGDKFYSLEFFPPRTDSGGVNLIARFDRLAIGNPLF
IDVTWHPKGNSGGDEVTASLTIASAALNFCGLDSMLHMTCINSTTEDIDKYLRKAKKQGL
RNILALRGDVSDSIDESVRHTKELKYASDLVKHIRKEFGNYFGIAVAGYPDGHPECSSYE
DDIRRLKEKLDNGGDFVVTQLFFDAETYFKFLRDCRNAGITAPIIPGILPIQGYNSLRHL
VQLSKLPVPQRILDTIESIKDNDEAIRKFGIVEATNLCKKLLASDDVPGIHVYTLNREEA
VVKLLKRVGLWHEESIYKSLPWRPSANGKRISEDVRPIFWASRPKSYVHRTMMWDEYPNG
RWGSSASPAFGELKDYHIFYLKNTSKKDELLKMWGEKLESVEDVYEIFTCFVSGERNKYG
YKVDALPWSNDALALETLFIKKSLEYINSKGILTINSQPNVNALPSTHEVFGWGGPNGYV
YQKAYLEFFISAERFKTLLEVLPNFPMINYHALDLSESINVSNSDHHQPIAVTWGVFPGR
EILQPTVVDPTSFSYWKDEAFALWTNQWANLYPEESKSRQVITAVVRNFVLVNMVDNDFI
QGGNLWKVLDQLFSLEADKAVY
>A0A090KS02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldibacillus thermoamylovorans|TrEMBL
MEDGRLVYESDEQYFYEAAIQFVKEGVCLLGGCCGTRPEHIRAMAEAVKNLSPVTEKKVI
KEKPIIQLIQIQQVHELSLVDIVKSRRSVIVEFDPSKTLPMSQFLSGVNVLKNAKIDAIT
LADNSLASPQINNVACAQIVKNRYHLRPIVHLTCRDRNLIGIQSHLMGLHALGIHDILAL
TGDPTKLVSFPGASSVFDLTSFDLIRLIKQFNEGLSYSGTSLGEKTNFTVAAAFNPHVKI
IFSAKIRSSSGIEAYLSNFSVFTIA
>A0A4S1WDC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas naasensis|TrEMBL
MAAPLFADVAGDIEVSFEFFPPKTEKMEETLWESIQTLSPLGPRFVSVTYGAGGTTRERT
HNTVARIARETAIPAAAHLTCVEATREEIDQVAREYWAAGVRHIVALRGDPPRAGERYAT
HPGGYENAADLVAGLRKLHPFEISVAAYPECHPDSPNPGADIDNLKAKIDAGATRAITQF
FFEPETFFRFRDDAARAGITAEIVPGIMPVMNFASVQRMSAMCGTAVPAWMGKLFEGLDE
HPAARQLVAATLAAELCRKLYAGDVRQFHFYTLNRAELSYAICHLLGLRPKVGAALVAA
>A0A7V8QDD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium brasiliense|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWQSGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTSMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A6L7IU82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eggerthella guodeyinii|TrEMBL
MTQIADIYRTAKAEGRQPVSFEIFPPKGDLSLEAAHAMAGQLADLVPDFISVTYSAGGSG
NKQATAEVAAMVQSDFDVPTVAHLTCADATDEGLSRTIGDLRRKGIQNVLALRGDAAPAC
GEPGAGAFRYAKDLVAVLAEEGFCVGAAAYPEGHIACIDARANVEHLKQKQDAGAAFFIT
QLFFDNAYFYRFWDAALAAGITVPIACGIMPFLGKAQIQRMVFMCGASLPSPIIKLLARY
EHAPDDLRRAGIEYANDQLVDLAESGVDGLHVYTMNQPDIARANVAALRAAWQR
>A0A807Z544|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas salmonicida subsp. masoucida|TrEMBL
MGFHSARQVEALNQSLADLSGDIGVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKNPA
>A0A7X0CQ42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. SP1R1|TrEMBL
MKITDHIANANGKTLFSFELIPPLKGQSIQGIYDAIDPLMEFKPPFIDVTSLREDYIYKE
HANGLLEKLSYRKRPGTVAICAAIMNKYKVDTVPHLLCGGFTKDETENGLVDLQFLGIEN
VLVLRGDARRGDASFVPTPNGHNYATDLLQQVVDMNNGIYLHEHSDVSLKTDFCIGIAGY
PEKHFEAPNLKTDFKYLKQKVDMGAKFIVTQMFFDNQKYFDFVNNCRANGINVPIIPGLK
PVTTSKQLINLAKTFHIDMPEDLCDAVNSCKVEKEVKDIGVEWMINQCKELIKFGVPVLH
FYTMSNAGPTRRIAEAIF
>A0A729G3H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. houtenae serovar 48:z4,z32:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7C8AWN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium|TrEMBL
MKIIDIINPATQFISLEYFPPKTREDWPGFFRTVQRLAVLKPLFASVTYGAGGSTNIDSL
EIVSRIQQEYGIETMAHLTCLGSNTSEVSQFLHGLAAAGVSNVLALRGDLPQDGSVETPL
PSPLQYASDLVSLIRSSFPAMGIGVAGYPEVHPEAASAVADLSYLKLKFERGADFAVTQL
FFDNNLYYDFVTRARAAGVTRPIIPGILPVVSLKVIKRIVSLCGATIPAEFLAELEQADQ
AGGAAAVQKVGVAHARRQAQELLAAGVPGVHIYTLNRAEVVVDLVEGLNFTGAV
>A0A667ILN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lynx canadensis|TrEMBL
MDHPTPKVLLTRPRCPSLRMWALEASSGRFSVPPSISRNPAMVNEPRGDGGPTSRSEGSS
SGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCCQSREQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDVCVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMWGEELTGEESVFEVFACYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A7X2ITK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia rivuli|TrEMBL
METPNFSIEFFPPKTAEGAEKLRVTRAKLSELHPKYFSVTFGAGGTTQTGTLDTVREIMA
AGEDAAPHLSCIGGTRESIRAILNEYKSHGIKRLVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQARSPQHDLEAFVRKVNAGANAAITQYFYNADAYFNFVD
QATKAGVTVPIVPGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTDLAKRLLAGGAPGIHFYSMNQAAPTTALWQRLV
>A0A6A2G1Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedens sp|TrEMBL
MSFISKLRSGKFIITAEISPPKGTDTSRMLGDAALLKGIADAVNVTDNQRAAMRMSPIAA
CSILQEKGLETIMHITCRDRNRLALQSELIGAFALGIRNVLVMSGDHPSKGDHEGAKPVY
DLDSVQLLGMIQELNRGVDLSGNKLDGKTDFCMGAVTNTELNEAGLLKLKKKIKIASFLQ
TQAVFDVKRFSEFIEKKSEIELKQSKQIKIIAGIIPLRSERSALFLNKVPGIRVPDDMIK
QIKDAKYPEVEGMRITSDIIKELRTLCDGVHIMPVGNHEHTKKLLEMAGLI
>A0A4S4G2S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adlercreutzia caecimuris|TrEMBL
MEPVASLFAPRSIPFSVEMFPPKGSLTLDAARKVVGGMALARPDFISVTCSAGGSGNGGQ
TIEVASLIQSEAHIPAVAHLTCVNSTRETVQAAIAELKAAGITTVLALRGDLVGNAQPGD
FRHGADLIPLLKDAGFCVGAAAYPEGHLDCLDLDEDLRYLREKQDAGADFFVTQLFFDNV
DFYRFRERALAAGVTRPVTCGVMPFLGKSQIQRMVFLCGSSLPSPIVKLLAKHEDDPAAL
RAAGVEYACRQLVDLARNQVDGVHVYSMNHPDIAQAAATALADAGFRA
>A0A1T5A8E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter sp. 22Crub2.1|TrEMBL
MPAISFEFFPPKTDEQREQLDAAVSRLKGRGPDYVSVTFGAGGSTLSYTDDTVKRLRADH
GLSVAPHLSCMGGTKAEIGALLDTYKASGCRRIVALRGDLPSGMATPGDFRYAAELVGFI
REHSGDHFHIEVAAYPETHPQAENALADLRHFKTKVDAGADGAITQYFFNADAYFRFVDD
VTRLGVKVPVVPGIMPIANFSQLRRFSEQCGAEIPRWIVKRMQAHGDDAAAVRELGADVV
AELCRRLLEGGAPGLHFYTINRARATTSVLDRL
>A0A2N3X9E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 5112.2|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLAYAAELVRLIKESGDFCVGVAAFPEMHPRSSQWDTDVQHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPKLSNARF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A143YPU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus flocculiformis|TrEMBL
MKIESKFQKKKPVLSFEIYPPKRDKAIQNIDETLAILSELNPDFISVTFGAGGSHTDNQT
VELAKRIKQQYGIDPLVHLTCLNSSKFEICELLEELKAADIDSILALRGDKNPAVEAKQD
FRYASDLVKFIRQYGDFSISGACYPECHTESKNKIEDIAHLKEKVDSGVQHLISQLFFDN
NAFYSFREHLQIAGMHVPVEAGIMPVINKAQIERMVTLCGASLPEKFSRVMHKYEDNKEA
LFDAGMAYAINQIVDLLAHDVDGIHIYTMNNPIVAKRICDGIKNLI
>A0A1G0SUX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium RIFCSPLOWO2_12_FULL_56_21|TrEMBL
MKQDFRQRLKKGPILCDGAMGTLLDLYEYAEQPREIHNATHPEIIERIHREYIEAGSEII
QTNTYGGNRYRLAEYHLADRVEELNRLGVEIARRAADDSVYVAGSVGPTGKLLQPIGKLK
LQEARDAFRQQIEVLLKAGVDLIMLETFVSLHELDEALAAAKELTKLPVVAQKTFPEDGA
ILSGSFPVEVAEHLLSRGADVVGANCTVGPQRMFSIITSMHKEGIYLSAQPAAGIPTLLD
GRALYHTSPEYLAQYARELLQAGVTIVGACCGSTPAHLREIKKVLDEFRSSPAGATRERT
PQIQVRERSGPADAADVAPDSRSRFARNLGTKFLTSVELDVPRGLDMSSVLDGARYLHRH
GIDAINITDGARARLRISSVALSHMLQRDVGIEAMMHMTTRDRNMIGVQAELLGAHALGI
RNVLFITGDPTNIGDYPQATSVFDIDSSGLIRSARAMNEGRDLMGNAIGQSTSFLIACAV
NAMADNMDAEMAKLEKKIEAGVHVIYTQPIYEMRTLESLLKRIDRWKVPIMLGVLPLRGF
KHAEFLHNEIPGMVIPERIREQFRSAGPKAQAVGIEISVKFLTEAKSLVAGAYIMPPFKK
YEIVPEILAASGVKPS
>A0A7Z2VVB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. GN2-R2|TrEMBL
MATPDISIEFFPPKTPEGAEKLRTARQQLATLNPKYFSVTFGAGGSTQQGTLSTVLDIQA
EGFQGAPHLSCVGATRDSIRAILRELHAHGIRRIVALRGDLPSGYGGAGELRYASDLVEF
IRLETGDWFHIEVAAYPEMHPQARSPQDDLQNFARKVQAGANAAITQYFYNPDAYFQFLD
NAARMGVDVPVVAGIMPITNYTQLMRFSEMCGAEIPRWIRLKLASFGDDSASIKAFGLDV
VSSLCERLLAGGAPGLHFYSMNQAAATTAICRRLQGA
>A0A0M9DCG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MSLKDTFKNKTVFSLEVYPPKTPEGTKKLVNALTGIKRIKPDFISITLGAGGSQNNNALE
LSSMIQNDLNIPAMAHIPGIYRSKKDVADFLKQLKQHNINNVLSLRGDINPDETPVGDFN
HASELAEFIKTQGDFDITGACYPQKHPESIDLVDDTLHLKEKVGNGVGHLITQMVFDNQA
FYDFRQRLKLAGINVPVEVGIMPCTNCNQIKHITELSGLEMPKKFVDIMNKYANNKEAMR
DAGIAYAVDQIVDLVANGVDGIHLYTMNNTYVAKKIWEATHSLFEATSYQLQHPSLSGSD
NQ
>Q2CBP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanicola granulosus (strain ATCC BAA-861 / DSM 15982 / KCTC 12143 / HTCC2516)|TrEMBL
MTTPAISFEFFPPKDLEGSFRLWDSVQALAPLGPDFVSVTYGAGGTTRQLTHEAVGTIHK
TSGLSVAAHLTCVGASREETLAIAEGYAEVGVTRIVALRGDPPKGSAGFTAHPEGFASSV
ELIEALAETGKFELHVGAYPEKHPDAATTAADVEFLKRKIDAGAASAITQFFFDAETFFR
FRDACAAAGIDAPIVPGILPIASWAGVRKFAASCGAAIPQVIVDAFENATRDGDTDLLAT
AVATELCDELLEGGVEHLHFYTLNRPELTRDVCHALGIAPRASLREVA
>A0A1R3R5T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus carbonarius (strain ITEM 5010)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDGQDPERDLPYL
VEKTRAGADFIMTQLTYDMEAYTRFESMLRNHESGAFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPQILSKLEEVRHDDDAVKRIGVDIISDLVYGIRDLGCTGPRGFHFYTLNLEKT
VSFILERCELIPPYSEIDDSDALADGGNLSAMDSSSYVAPNGAQIRSLASRRSSVSSIPH
NRVIVDKVQISETSSKGSVTHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVPAPIARQIWGYPVSRDDISTLFRRHVSGELYMVPWS
EGGAEENSNGLNAETAVIQTELLTLIDKKGWWTLASQPAINGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPDKDYQSVLKPLFQKHGHEKLAWFATNVKGDFESSLPGPNPDDPDPIDIN
PANVNAVTWGVFRGKEIVSPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLNQTK
NDVWLVCVVGQEFGAGTEAGSEEEDDEKKWMWRELANSQ
>A0A0S8FNB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR_3 bacterium SM23_42|TrEMBL
QLLKTIRQMEAGKDLGDNELDGAVEFCAGAIVTPEANPIEPQLIKFEKKVEAGAEFFQTQ
AIYDLEKFAKFMEYARQFPVKILAGIILLVSARMATYMTENVPGVFVPQNLIDELAAAPK
GEAINKGIEIAGRMIATIEKESICDGVHVMAIGKEEVVPDILKAAGLAT
>A0A1M3KHY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium 44-23|TrEMBL
MERRLKAGEFVVTAEVQPPQTVSTNRMKDNINLLRQYVTAVNFTDGASATPRMSSWACSS
LALKSGMEPVLQIAARDTTRVALQSEALGASALGIRNMLCLTGDSNQLALRPRGRMDIYD
LDSIQMLWILRRMRDEGKYLDGREIKFPPKFFLGAAASPHASRPEFQAIREHKKVNAGAQ
FFQTNLVFDIECIEIWLNELSKRNFLDKIFILIGLSPLKSLKMAKFMKEKVPGVFIPDAI
LHRMAVAEEAGNATEEGVQITLEMIVNIRKMQEVHGIHIMTVGWEEIVPRIVSESGLLLN
>A0A0C2WKJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MPLQYSFEITPSIDRVNLDGLLNLNPEFISITDRNHDMDNLMQSIQISDYIHANSSVDVV
IHLTGIDKDEKRVKEMIDLMQQHDIHSVLALRGDKLSQNDTAVTFPHADRLIEFIKQQYP
HVNISGTCYLNSSDEEMKWLRQKIEKGCTNIISQFSFDANDYFDYLNQIEIDTPIWFGIM
PVIGKSQTQKMLELTHSTAPDELNVLMTQHDDDFGEDGVKYTAGMINKIRQAGANHIHLY
SLNNAENTEKIINKI
>A0A258FWG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. 32-62-10|TrEMBL
MPPPLIHPNWSRPATSAIDGYSIEITAKDAEALRAVAPRIPQATPVAIAFLPGETLDARV
RAAQTIRALGFEPMPHFSARRIGSRAEFEDYLAAVVEQAGVQRCFVVAGDPSTPAGPFAD
SASLIATGAFERSGIRAIGVGGHPEGHPNMTEAECFAVLDGKCHEIERRGMAPLIVTQFG
FDADAVVRWLSELRGRGIDAPVRLGVPGPAGIKTLMRYAALCGVGASTAVLRKYGLSLGN
LIGSAGPDRFVAILETALTPGHGPVRLHFYPFGGLARTLDWIDGYARATGLDPSA
>A0A1B6W190|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eikenella halliae|TrEMBL
MQHNTLSFEFFPTRTPEGREKQKTTRKQLSQYRPEFFSCTSGAGGTTREGTMQTIRDILA
EGMAAAPHIPCVGLDAGELTDLLQEYKDLGIRHLVALRGDIPSGMGLGSTGLHHANELVE
LIRHRFGDWFHIEVAAYPEYHPQSRSAADDIQSFVRKVKAGADSAITQFFFNADAYFRFL
DDVRGRGVEIPIVPGIMPIANFSKLARFADMCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCGRLLRHGAPGLHFYTLNQAGLSSTICQRLGY
>A0A292G565|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGLEGLSPDFISVTYGHGTHSDRTATARIANTIH
GEYGIPAVAHLTALYSDEAKIDEALDMFEAAGASAVLALRGDYIDGDEPVGRFNHASDLA
AYIRDRKPGLKVFGACYPEGHYSAASLDEDIENLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGAKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGII
YASDQIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFTVE
>A0A6L6H7F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia sp. CPCC 100877|TrEMBL
MSFFHANQREALNQSLAELHGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASREELRTIARDYRDNGIRHIVALRGD
LPEGSGRPDMYAADLVALLKEVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNYKQLQKFATMTNVRVPKWMDSMFD
GLDNDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPIAVC
>E0XQ62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium HF4000_009C18|TrEMBL
MEYQSLLHKKLSEGIFVFTAETTPPDASNQEVLLKKTMPLKGVADAVNVTDSPGAKVHMS
SLTAAIILAQNDIEPILQLTVRDRNRLALQGDLVGASALGVHNILCLSGDDPKVGDQPET
KPVQDINSATLVTTANMMRKDKQFPSGRIIDPPPKLFIGGAEVPSKGKPNTKKILNKIKI
GVDFFQTQYIFEKKKLIDYMKVLDDVGILEKTYFLIGLGPFASAKSAKWMNDNLFGVDVP
DEIIKRLEQAKDQKEESKKICLELIQIFREIKGVKGIHLMGHKKEELIAEIIKESKIS
>A0A1E7PCS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. BCW_4722|TrEMBL
MFEVAPSTRLSASAPLDREDTSPLIRRPRPRPRTALSFELIPPRNDKDAEKLDALIAGLA
AYQPDYVSVTSSQRSEWLEGTAALISRIADTTELRTIAHLACTAGTRDELAEWIRTLIDA
GVRGFLALRGDLPEQGLPDGYLRHATDLLNLIQDVQEEEAYRLAAGKLALSVACYPKGHE
ESRSFDHDLDVLLTKQRLGADFAITQLFFEAEDFLNFVEVARLAGVRIPLIPGIMPMTSL
KRVQRMGQLSGIEVPERVEKQLLQAATPEEEYEAGMRMTAQLAKDILQAGTGGLHIYTHN
NLDVTRDFLNRIGIH
>A0A7V9Q2J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIDELLATSPEPSFSFEFFPPKTPDGERNLEAALAELSHMAPTFVSVTYGAGGTEAQKR
QTIEIVGRIKRDHGLETMAHFTCVGATESELRETLDLMTATGIDNVLALRGDPPQGETEW
TRTEGGLSFSRELIELISADYDFSIGAACFPEVHVHADDADSDLRHTKAKVDAGARFLIT
QLFFENALYYDFVARARALGIEAPIIPGIMPITNYAQLKRFTDMCGASIPAALRAELESR
ADDPDAVADFGVAYATLQCADLLANGAPGVHFYTLNKSPATRAILSALRTMSPWASRPVA
SAPGAALS
>A0A7V9PNA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIDELIATSEEPVFSFEFFPPKDEEGEYSLLAALYALRSLKPTFVSVTWGAGGSGRLKT
IGMTQRIRDQVGLEGMAHLTTVGATVEDLHTTLREMVDVGIENVLVLRGDPPRGQNTFVA
AEGGLSYASELATLVADHHDLCVVGACYPEVHPESTDLASDLEHLRKKVDAGASVLITQL
FFDNSVYEHFVEEARAAGIDVPIIPGIMPVTNLEQIKRFTQMCGASLPDGFRTALEGRAG
QPEAIIELGVAYSTLQCADLLERGAPGIHFYTLNKSPATRAILSALRLMRPWERSRAYA
>A0A840V7Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidocella aromatica|TrEMBL
MTHSPTPDTLERWASGTRIAPLPTREGLAPPAISFEFFPPKTPALEAQLWTCIERLATLR
PNFVSVTYGAGGSTQERTHATVLRIVQETDLTPAAHLTCVGATREAVDDVARRYWEAGVR
HIVALRGDAPNGENYVPHPGGYAFAADLVTGLKKVADFEITVAAYPETHPQAASPEADLD
NLKRKLDAGATRAISQVFFDNAIFLRFLDRALAAGIKAPIVPGIMPVTNFTQAEKFCAAC
GTSVPKWMAGMFEGLDDDVETRRMVSAAVAAEQVRLLQANGIDEFHFYTLNRPDLTYAIA
RILGVKPQPKAA
>A0A7X0DBP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhizobium flavum|TrEMBL
MFRNDATTENSASLASVLTDCSIEVMPRTAAKISDFRQILPEGTRVYVAHIRDTPIDDMV
ATARRLTEEGFQPMPHLPARIIPDRLTLETWVRRYREEAGVTQALLLGGGVSTPAGDLDS
SIAMLETGVFDRLGFDRLHVAGHPEGNKDIDRDGGTGVVDEALKWKQSFSERTDAEMAIV
TQFAFEAAPVIAWAERIAAAGITLPIHVGVAGPTKLQTLIKYAVACGVGPSLNVLQKRAL
DLRKLLVPYEPTDFLVDIAAHRAAYPESSIERVHVFPLGGIQASADWLARVRDGASHQD
>A0A1L9Q2K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus versicolor CBS 583.65|TrEMBL
MEKITDKIAALPPNANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRQKYGDYFCVGVAGYPEGHPADSFQDVQDPKVDLPWL
VEKTQAGADFIMTQLTYDIDAYTDFENLLRNHESGAFKTIPIVPGLMPIHSYKILTRVTK
LSHVRIPPPILQKLEEVRHDDDAVKRLGVDILAELVEGMRKLPTPRPRGFHFYTLNLEKT
VSFILERCKLIPDYTDDDAVAVSEEVSLLTANAAKAASSGRRRRASSLSSLPHNRVIVDK
ISEPSSKESVTHEATAASAGMPAQPPDRNTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVAPSVAHRIWGYPVSPEDISKLFRGHVSGDLHMVPWSEGGAEENTS
GLNAETETIRPELLALIDNNGWWTLASQPAVNGVRSDNSIFGWGPPGEGFVFQKPFVEFF
CPTSDFTNTLKPLLQKHGHEKLAWFATNANGDFESSLPAQTSDTEPIEMNPNNVNAVTWG
VFRGKEIITPTIIEEVSFRAWGDEAYRIWDEWRRIYPRNSPTERFLEKTKNDVWLVCVVG
QDFGAGTEIGSKEEDYERKWMWKILANC
>A0A2W5XZP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIDSILESGEEPVFSFEFFPPKSEDGERNLYAALEELRTLEPNFVSVTWGAGGSTREKT
IEIVTNLRERFGLEAMAHFTCVGASVDDLHDSLRQIEAAGIENVLLLRGDPPQGEERFEP
APGGLSYASELAELVAAAQYPFCVVGACYPEVHQEAAGPEADLEHLVAKVRAGVRVLITQ
LFFDNADYFRFVDQARAAGIDVPIIPGIMPITTIAGIKRMTSMCGACIPPALQHELELRA
EHPEAVVELGVSYATLQCAELLARGAPGIHFYTL
>A0A330MK97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aequorivita sp. CIP111184|TrEMBL
MKVTEHIKNGNGKTQFSFEILPPLKGENIHSIFENIDPLLEFKPPYINVTYHREEYVFKD
LKDGLIEKKVVRKRPGTVGICAAIQNRYEVDAVPHILCGGFTKEETENFLIDLQFLGIDN
VMALRGDAVKSETYFSPEKNGHKYACDLVSQINFLNKGAYLDDELQHTFPTDFCVGVAGY
PEKHMEAPSSESDIHFLKKKIKNGAEYIVTQMFFDNEKYFKFVEKCRAEGITVPIVPGLK
PIAVKSHLNLIPHRFKVDLPDALVMEVVKAKDNKAVRQIGIDWCVKQSQELVKAGVPFLH
YYSMGKSSNIKEIASQVF
>A0A1I9Y3I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. 1_2014MBL_MicDiv|TrEMBL
MANHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEEAAPHLSCVGGSRESIRAVLADFKAAGVNRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGANAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAATTALWQRLVK
>A0A2G8HTX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovorax sp. JY17|TrEMBL
MKIIEHLDKAKNKELLCSYEIVPPPRGRSVQDIIDIVEALQPYNPPWIDVTSHAAGAFYN
EKADGSIERKVFKKRPGTIGICGIIQNRFNIDTCVHLLSLGFTKEETEDALIELNFLGIH
NVLALRGDAPNYNKKIDNGRHTNNYAIDLVKQINEIKKGEYVSDISGARPLDFCTGVAGY
PEKHFEAPNMKFDIQMLKAKVDAGAEYITTQMFFDNEKYFAFVKECRDAGITVPIIPGIK
IIKNVNQLASIPKHFYVDFPNEFVDEVMSNQEHVKDIGLEWAIKQCQGLADAGVPCLHFY
IMNDTKSVIKVVEKFR
>A0A483AGH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium endosymbiont of Bathymodiolus sp. 5 South|TrEMBL
MPMKTSFEFFPPRTEKGKQTLHQVRQELSSLNPEYFSVTFGALGTTQEATLETVLDIQKN
DTVAAAPHLSCIGSKKEIIIELLDQYKAANINRLVALRGDIPSGVRDIGDFHYANELVEF
VKSQYNHHFHIEVAAYPEMHPESKNRLTDLQHFADKVSAGADGAITQYFYDADAYFKFVD
ATEKLGINIPIVPGIMPITNYTQLVRFSKMCGAKIPSWILKKLELYQDDLDSLSAFGLEV
VTNLCQTLKAQGVNNFHFYSMNRSQPSLEIAKHL
>A0A0T1UK47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Root1310|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFYAPKTPKGERSLWNALRRVEAVAPDFVSV
TYGAGGSTRATTVRETQQIVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDTDVTHFVD
KCRAGADYAITQMFFEPESYLRLRDRVEAAGCVTPVIPEVLPVTSVKMLESLPKLSNAHF
PAALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>R5R707|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:646|TrEMBL
MKLSEMMKEKQLLSFELFPPKTDKGMANLPGTIEKLCEFKPEYISCTYGAGGTNVGKNMD
VCKMIQDAGTVPVTHFTCIGNTREGIKDQLQNYLDNGVDHMLALRGDLPFGWTGTGGDFK
YATDLVAYVRKEFGDKIEIAVAGSPEGHISCRSLDADVAVLKQKQDNGADYIMTQLCWDM
EQFKRWQDKIDKAGVTMPVDVGIMPILDQAATINMALSRNACVMPRALCELISKYWIFPN
PFDKEPFDAAAEQKKADFKKAGIEYTIKQIDEYRALGVNGIHLYALNKWKDVTDIINESG
IRTLV
>A0A4Y8R8D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulosimicrobium funkei|TrEMBL
MTSEASFAHRPGRPRPTVSFELMPPRRPDAAPKFWETARRLVATHPDFVSVTYGAAGTDR
ATARQVVGRLLQGTPVLPIAHLTCVGASREDVESVITDFLDEGVRSFLALRGDPPRDQPD
WQPAPDGVRSSTELVALLREVEASRCASDPAVALRGAARPLTIAVATFCDGNPAAGTTRT
QEVRRLWQKQQAGASFAITQLFYDASSYTDFVAEARAAGVTIPILAGLLPTTEPARLRRV
EELTGVRAPQHLLDALDALPDPEAQHAYGIAYSVDLAQRVLDAGTPGLHVYTFNKHRAAL
DLLEGVHLGGGSVGTGGGASAAAAPLVPDLASGPWVTGTSLPTTSAATHGAPV
>A0A1P8Y690|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces autolyticus|TrEMBL
MATDQEGSAPRTARAAVAHALRNATYEILPFKSAEEKVLAHVPTDVALTVTTTEAKGLGP
TIDLAASLSKQGYSAAPHIAARLVRDRAHLSDIVDQLRDSGIDRLFCIGGDAAEPVGDYV
DALSLLQGLRDLDHPFSSIGIGGYPEGHGSISDELIERALESKAPYADLIITQLCFDADT
TIRWARKAQDRGVTLPIRVGIPGAISRQKLIRVSAGLGLGQSARFLKKQQTMFWRFFLPG
GYSPNKLIQKLTSAFAEQDNNLRGFHVFTFNDLDSTEAWRKAWLARLT
>A0A8E0D4M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae PID332|TrEMBL
MNYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRPVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A7X6NTT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium sp|TrEMBL
MSSRVSIGDLLAHASGPTFSFEFFPPKNEAGQQLLTRTIAELEPLEPDWVSVTYGANGSS
RQRTLDATMAILASTELTVMCHLTCTGQTIDELKAVIDAYADAGVTNILAIRGDMPGGAS
VAWEPYPGGLQTATELVELVASRGDFSIGVAAFPDGHATSTPELDAQILLGKQQAGASFA
VTQLFFDLGHYFELVGRARSAGCTIPIVPGIMPVTSVKQLGRFVEMSGADIPAKVAERLL
SVADDPEQVRITGVELAAELCDRLLAGRAPGLHFFTQNRSRATREILAKLRDDHQ
>A0A2T9YB81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium simulii|TrEMBL
MGDIQNCNFLNFTSANPFYAIETSIPNTFEGLSAFRNSLDILTSLNTSYVGLNWNPPDST
FSNSTDLAAEIKDDYNVQPQLRIHYNNMTRNEIDDALKASLVAFI
>A0A2T9Y2R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium simulii|TrEMBL
MGDIQNCNFLNFTSANPFYAIETSIPTTFEGLSTFRNSLDILTSLNTSYVGLNWNPPEST
FSNSTDLAAEIKDDYNVQTQLRIHYNNMTRNEIDDALKLVKSKGYYSILAVQNYGPESDG
SDEFDEYNESDEPHEYNESDEPHEYNESDEPHEYNESDDYNDSYGKDVYTNSSSVKPDFK
CAGELIEYIQKNPDFKDAFKIGIIGSPDGLNKNNSDNNSDSNSGNSENEDDGLNLDEIKS
LVDTVNKGAHFVVTRPFYNTKKFIKWYNKCREMGIKVPIIPSFFLIRDYESFKKVKEQFN
LCVPRFLEKRIEEIKHDQRKLKKLGAMFLIKQIKQVKRSTDVIGYQISATELCKVIKKVL
WKSELLKPKDRESLNFDLIEE
>A0A667WB77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myripristis murdjan|TrEMBL
LINSNSDSSGASNSGGESSKESSRCSTPVLDADRSDRLRDKMLRRMESGDRWFSLEFFPP
RTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLETILH
LTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKHIRSEFD
DYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRAETFLKFVRDCRKIG
IMCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIEQAVEMCR
LLLESGEVPGLHFYTLNREVATIEVLRQLGMWIEDPRRPLPWAMSAHPKRKVEDVRPIFW
ASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEELTS
EDSVFEVFTCYITAQPNHSGHKVMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQPN
INGKPSSDPLVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVQGHN
LTNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRM
IIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDMPPELVTDGAVSE
>A0A7L9BTI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaeraceae bacterium|TrEMBL
MDIRDVFQSRRTTFSFEFFPPRTAEGAGDLFGHIKEFEKLKPTFVSVTYGAGGSTRQLTH
DLVVKISTTTPLDPMPHLTCVGHDEREIDEILSSYAAAGINKILALRGDRPKGVTGDEPF
KHFRHAADLVGFIRKFNESGRHPDRRGFAIGVAGFPEGHPDTPNRLEEMDRLKAKIDRGA
DFIVTQLFFDNRDLYDFRDRCELAGVRTPIIAGVMPITSIAGMKRMADLAAGARYPAPLI
RAINRAGGNDAAVRRVGVHWATEQCRDLLDHKAAGIHLYTLNKSTATREIYATLGVENSL
QLI
>A0A674ANI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmo trutta|TrEMBL
MPKSSILVSSDHNTFTSCPLNHSDVHCSMVNNVQRVDDNWRTCTKSDSSGKRNSGGESSK
ESSRSSTPVLAADRTERLRDKMRRRTESGDHWFSLEFFPPRTASGAVNLVSRFDRMGSGG
PLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQTKETITGYLSKAKH
LGLKNIMALRGDPVGADWEEEEGGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESY
DEDLRHLKEKVDAGADFIITQLFFRTDTFLKFVRDCRAIGITCPILPGIFPIQGYQSLKQ
LVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGIEQTVGMCRVLLESGNVLGLHFYTLNREV
ATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNG
RWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEELTSEQSVYEVFTSYIKAQPNCAG
HKVMCLPWNDEPLAPETNLMMDKLDKVNRRGVLTINSQPTINGMPSDDPIVGWGPPGGYV
FQKAYLEFFTSSENVTVLLKVLKKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGR
EIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFP
LDNCLWQVIDNMFELLDNPPEEQPTEQPAEQPAEESPVEDQPTK
>A0A7C7QWU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquificaceae bacterium|TrEMBL
HGALVAVLLGIIAANVLALRGDVPRDKPDWRPPKGACKYAKELVELIKEKFNDKFSVGVA
SYPEGHPESPNLEWEVKFFKEKVEAGADFSITQMFFVNEYYYRFVDVCEKAGINIPIIPG
IMPITNFKQIRKFASLCGATIPQNLIDKMEKVEGNSEEIKKIGVEFAVNQCLDLIEQGVP
GLHFYTLNKSDATLKIYEAIKEKIPRKV
>U7ULD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera vaginalis|TrEMBL
MTASPSFPDRKTFSLEVFPPKAASPLEPMIAVLRELSELKPDFISVTCGASGQGGTRTAE
VAEKIITDCKLTAVPHLTCLNLTAAEVLAVLNDYRQRRITNLLALRGDSVPGLEPAAVFP
HAIDLIRFIKEQTGDEFNIAAACYPEGHLQATSLDDDIHYMKEKEAAGAGKFLSQLFFDN
TIFYRFRERTAAAGITAPIEAGIMPVTSKSQIERMIALCGASLPQKFRRAIDAYGDDPTA
MQDIGIAYAIDQIADLLANDVDGIHVYTMNNPDVTRKIKDRIQSLL
>A0A4R7WBR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. LP_7_YM|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARTLAGYNPDFFSCTYGAGGSTRDRTINTVLQLE
QEVNIPAAPHLSCVGDSKADLRTLLSQYKEAGISRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGSHFHLEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFH
FVERVQKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQVITEMCDRLLQGGAPGLHFYTLNQAEPSLAIWNNLQLPR
>R9HMD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus dnLKV7|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKDGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVEAGADYVVTQMFYDNRKYVDFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAMKCKDDKEARALGIEWCINQCRELIAYGVPGIHF
YTVGAVDNVKEVATAVY
>A0A449D7R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei|TrEMBL
MVESTAVRLLEDFSLEMTGKDVANLQEAASAIAPGTRINVTYLGNEDLPMRVAAAKAVGE
LGFTPVPHISARRVTSEQALRDFLAALAEVNATERVFVVGGDPATPEGPYPDSLSIIRTG
ILQEYGVREVSVAGYPEGHPDIDTATLWEHLRAKTASLAEQGLGQVVISQFAFDAERVSE
WVAEVRDAGVTGDIRVGTPGPAGVKRLIGYAKRFGVGTSAGIIKKYGFSLANLVGTAGPD
RFITELAADKPVAGDGRGVKTHFYTFGGLSATAEWIRDFSRGA
>F8AZN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Frankia datiscae|TrEMBL
MQESTAGRERPARGFELICEIEPPTRPDLTHARHQIGVLSPVTDAFLIPDNHIGRATVSS
IAVAHEVQTMGGRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVHGDKPTAGNRTSDL
TVRAMMDEARAASEDPVFADMPAFRVGAAAGLRPLLAWKRAADFLFVQVSYSVDALLRWR
DAHPVELPVYAGVMVLASAGMARRLAATIPDIDIPDDLVEAVERDQAAGVEAACDQVLRL
RDSGAFAGVHLVPVSRYRQVATRFEDLL
>A0A1M5UH10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 3214.6|TrEMBL
MGGDGLSTLLRNDNVRYEVLPAKATEDKVLAHVPSDVVVTVTASPVKGLEPTLDLAGRLA
AHGYRVVPHVPARLLRDDRHLKEVVDRLREAGVDDVFVPAGDADPPAGAYDGALPVLRGL
SELGSPFSRVGVTGYPESHPLIHDDVTVQAMWDKREHATYIVSNLCFDPRVLGEWVARIR
RRGVTLPVYVGVAGPVQRAKLLAMATKIGVGESTRFLTKHASWFLRFATPGGYSPERLLE
RAEPALTAPAADVPGLHLFTFNQIAETERWRRALTDRLAG
>A0A350D2B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquificaceae bacterium|TrEMBL
MKIGQYLKEGNFSISFEFFPPKTPEGEEDLFQTIKSLRAINPSFVSVTYGAGGSTRDRTR
RVVERIHKETDLTVMAHLTCIAHSKEELLQIIEEYREIGIENLLALRGDRPANMPDFRPP
EDGCTHADQLVRLIRENYGDWFSIGVASYPEGHPESPNMEWEIKYFKKKVEAGADFSITQ
MFFDNRYYYEFVDLCQKAGIDIPIIPGIMPITNFRQVQKFASMCGATIPQRLIERLEPYA
DSPEETLKIGVEFAIEQCLDLLENNVPGLHFYTLNKSKATLMVYEGIRGALKA
>A0A0M0KKH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus halodurans|TrEMBL
MTNLVEALKTNILVGDGAMGTLLYEQGIDRCFEELNVTDPEKIVAAHVAYVEAGADVIQT
NTYAANRMKLAKYQLDDQVLEINRAAVRLARKAAKQETFVLGTIGGIRSIQFEEVEIQEV
QDVFLEQMKALVSEGVDGLLLETFYDLEEAKLAVSLARSLTDLPVIAHLSIAEIGVLQGG
KLLEEAFAELEGLGADLVGINCRMGPYQMLRSLETVQLLDRAYYSAYPNASLPDYRDGRL
YYHSNPEYFYEMGKRFVQQGVRLLGGCCGTTPEHVRAFAKVVKGLKPVVSKPVRLEIKET
LSSTGQKTAREPLAEKVKKQPSIIVELDPPKNLAIDRFVEGAAALKNAGVDAVTMADNSL
ASPRVDNLALGAIIQQQVGARPLVHVTCRDRNLIGLQSHLMGLHALGMTDLLAITGDPTK
VGDFPGATSVYDVTSFQLISLIKQLNEGISFSGKELGQKANFSVGAAFNPNVRHLERAVQ
RMEKKIEAGADYFMTQPIYNEKQIEDIYEATKHIEKPIYIGIMPLINGRNAEFLHNEVPG
IKLTDQIRERMARAGEDRQKGEREGLAIAKSLLDVATHYFNGIYLITPFLRYGMTVDLTH
YVKETHHQIRQPERSVQK
>A0A1F4ALK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_63_19|TrEMBL
MESQKRHPRNFSFEFFPPKTPEGVQRLSATWRQLAQLQPRFFSVTYGAGGSTRDRTLATV
TEIRQAGFHAAPHVSCVGSSRADIAETLDLYRAQGIGHIVALRGDMPSGAASMGSFHYAN
ELVEFIREHTGDHFHIDVACYPDFHPQAKSPQDDLRNFKRKIDAGANSAITQYFYNADSY
FRFVDDCEAIGIDIPIVPGVMPINNYTQLARFSDACGADIPRWLRLKLASYHDDIASIRS
FGLDVVTDLCDRLLSAGAPGLHFYTMNMAGPTSTIWQRLGL
>A0A4S8NR07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides caeni|TrEMBL
MTTGAGRSLGEILREGGRSFSFEFFPPKDEAGEAQLWDAIRALEPYQPTFVSVTYGAGGS
TRDKTVAITGRIARETSLVPMAHLTCVGHTREEIEGILDSYVAEGVSHVMALRGDPQEGP
RAEWTPTDGGLDYAIDLVELASRRGDFRVGVAAFPEGHPSAASLDADADVLVAKARAGAE
FAVTQMFFRAQDYFDLVGRVRDRGVDMPILPGIMPILNLAAIRRQGELIGTNVPQDVVDR
IAAFDGDPAAVRAEGIKVAAELCDELLAGGAPGLHFYTLNRSKATLEIFEALQITV
>L4IVQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli KTE146|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>H6SN05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararhodospirillum photometricum DSM 122|TrEMBL
MNAKLQPVIGAALPAHDLSVSFEFFPPKTEAMQAQLWDCIQRLEPLAPAFVSVTYGAGGS
TRERTHETVARIRQETRLEPAAHLTCVAASRDEVDAVARAYWESGVRHIVALRGDPPEAG
TRYAPHPEGYAFALDLVQGLRRVADFEISVAAYPEGHPEAPSLEADIDTLKRKIDAGATR
AITQFFFDVDAYRRFMDRVAAANITVPIVPGILPVVGFATAKRFAGACGASVPAWMDELF
DGLDNDPETRKLIAAALAVEQCRLLMADGVRDFHFYTLNRPDLVQAICHALGVRPQAAHG
SHGA
>A0A7W1LBW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRNFRELLGGDGIYVFDGAVGTRFYDKGVYINRSYDELNLTAPDLVREVHTEYVKAGADI
IETNTFGATHHRLLQYSLENKLREINVAGARLARHAAGENVFVAGAVGPLDLRIEPYGPT
SFDEAREMFKEQIAALLEGSVDLFVLETFSDLSEIQQAIKAVRELCDLPIVAQMTIATDG
KTIFGADTEILAGRLDEYGADVIGLNCGVGPTHILTALEKMRSVTTKKLAAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRFIKAGASFIGGCCGTTPQHIKLISDAVRAVSPRQSKAVKP
TTETVKVIDLKPVDVEIIPPEMRSKWSRKIALGEFVTSVEVLPPKGCDAAKTLESIKLLK
TAGVDAVNIPDGPRAQTRMSAQATAILVEREIGIEAVLHYCCRDRNLLGMMSDLLGAAAL
GVHNLLIITGDPPKMGPFPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGRPTAFSIGV
GVNPGAINLEEEIRRFEWKVEAGAEYAITQPVYDTKQLRDFLKRIEHVRIPIVAGVFPLV
SIRNAEFMHNEVPGVVVTQEILKRMRVASDKSKEDARDEGIKIARESLTEVRDLIQGVQV
SAPFGNVKYALQVFDVLDELKSIGEAATIS
>A0A7Y5WT07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MALPDFLGELDTRVLVCDGAMGTMLYGRGIFLNRSFDELNLTQPDLVAEVHQAYARAGAD
VIETNTFGANRVKLAAFGLAERVHAINAQGAKIARHAARENAYVAGAIGPLGIRIEPWGK
TGVDEAEDIFREQARALVEGGVDLFVLETFRDANEIGAAIRAVRSVCALPIVAQMTTEED
GNSLDGVAPETFVPDLEHAGADVVGLNCSVGPAAMLETIERMAHVAHVKLSAQPNAGRPR
EIEGRNLYLCSPEYMASYARRFIASGVRLVGGCCGTTPDHIRQIKIAVRALAPAAVRQKP
GAAARQTREVRVATVPRAQKSRMANTLERGGFPISVELVPPRGYQSDALVEQARQLKIRG
IDLVNIPDGPRASARMSALAAALLVQQQAGVETILHYACRDRNLLGMQSDLLGAHSMGVR
NVLLVTGDPPRIGDYPDATAVFDVDSIGLTNVVAQLNRGLDIGGQPIGQPTAFHIGVAVN
PAAFNLDEELRRFAYKVEAGAEFAMTQPVFDLTEFRAFVQRLGPHRIPILAAIVPLESLR
HAEYMANEVPGVRVPDAVIARMRRADADGRAAEEGLAIAREIAGDLRSLVQGVQISATPK
AIHVALGVIDALGA
>A0A3E0PDZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKKFKELLESDSVYVFDGAIGTRFYDKGVYINKSYDELNLTSPDLVREVHGEYVANGADV
IETNTFGATRHRLKQYSLEGKLHEINVKAVQHAKAAAGDKAFVAGAIGPLDLRIEPYGPT
SLEEAKEMFAEQAAALDEGGVDLFILETFADLSEIRQAIEGVKSISKLPIIAQVQIQTDG
KTVFGATAKMIAERLDEWGADVIGLNCGVGPTHVLSALEEMRSVTNKKLSAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRYIKAGASFIGGCCGTTPKHIRLIADSVRAISPRSSRIEVR
DSTPAKEKIAQAQVEPVSPLERSNWSRKVAQGEFVTSVEVLPPKGVRAKKTLQSIEILRV
AGVDAVNIPDGPRAQTRMSAQATAVLVEREVGIEAVLHYCCRDRNLLGMMSDLLGAAALG
LHNLLIITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGDPTAFSIGVG
VNPGAINLEEEIKRFEWKVEAGAEYAITQPVYDTEQLHEFLNKISHVRIPIVAGIFPLVS
SRNAEFMHNEVPGVRVTQDILERMRQASDKSKEHAREEGLAIARESLEEIKNVIQGVQVS
APFGNVKYALKVFDVLDSFSEGERVTATTAGIEE
>A0A2I0CJG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas hunanensis|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQVARQVCPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQASPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALETRIEHWQSQVQSLEQWAPA
WHASWQMPGLPAVTFHPPQAGWRLDESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPLWATRAGAHVLHTLERNVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QWLSPQPLPRSQPES
>A0A7W9USQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces echinatus|TrEMBL
MNPALTESPEGTTPRPRGAGSPGRGACLLDDFSLEMTGKDVARLEEAGGSIPPGTRINIT
FLAGEDTATRLTAARAVKRLGFVPVPHISARRLPSRPALEEFLGGLAADGTAENVFVVGG
DPARPEGPYADALAVLRTGLLHDHGVRHIGITGYPEGHPGIADHELWSALTDKAAAIDAG
RFTGDVITQFGFDADPVLTWLEALRARGVRLPVRIGVPGPAGVRRLLGYATRFGVGTSAS
VARKYGFSLTNLMGTTGPDRFLHSLADRYDPARHGAVKVHFYTFGGLRTTAEWITRFPQQ
SAPATHSS
>A0A7V9LXY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MTRSIAARLGGPDPSFSFEFFPPKDAAAERQLWQALRELERLRPSFVSVTYGAGGSTREG
TVRVTEQIATDTTMLPMAHLTAVNHSRAELRHVLGRFAAAGVSNVLTIRGDPPGDPGAEW
VKHPDGLAYAEDLVRLAKSSGDFCVGVAAFPYKHPRSPDLDSDAHYLVRKIQAGADFAIT
QMFFALEDYLRLRDRVTTLGCDVPIIPGIMPVTTMRTIERSSQLSGAPFPPKLRQRFEAV
AEDPAAVRAMGIEQASELCQRLLAAAAPGIHFITLNRSTATREIWSNLQSRVSV
>A0A7Y2FEJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MISGDHKQIASELVVDGSVEFSHGDVEQIEAIAERLPYQMPVMVPCLPRRPLESMLPALQ
AIQEASLEPVPHIPARHVESTRALAKFLQQAGVRKAVVIGGDRSSANGPFADATALLSSG
CLAENGIREVGFAAYPEGHPTIPAEALFNSLSKNIDLASGQGQGSFIITQFTLSPQRIPD
LCSRLASAAPDTPVYAGIPGPATHEQVVHFARYCGVSTSLTAVSGVGVKLAQVVDHERPG
QQLGLLASYCAAHPGSNLVGVHIYGFGGMGETAKWIRRHINP
>A0A7W0KIK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MIPAGDGRLRTALHSGRFAVTAEIGPPRGADAEAIAAKAELLRDWVDAANITDNQGSHTR
LASWAGSILALRSGVEPVMQLTTRDRNRIALQSDLISAGAVGIPNVMMLSGDHPTFGDHP
DAMPVFDLDSVQLIWTARLMRDQGRLLSGKPVKPAPHWLIGAVENPFAPPLRFRAQRMGK
KVAAGAEFIQTQFVFDLDTFGRWMGEVTDLGLEQRCGVIAGVGPIRTVRAMEFMQSKVPG
IHIPDHVVRRLRGVPSDQVAAQGMALCVETIETLRETAGVAGVHVMAFGHEQVVPELLER
AGIPPRTATAPTVTGRTHDAG
>A0A7H4GU23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hominis|TrEMBL
MTVQLRLRDASRRCPKRMVYGPCGGVGADGGCEVPGIRCSFAADPDLLHTLDVSAADVAA
PESAEPSGDALPLSPRRTAAAAFATRVSEGLLVTADLPVRSADAGVLAEAGARLAGLTAV
IAGEPPGLRASLSPTHKALVLGGAGATVIAGITCRDRNRVAIEGELAALADLGVAGVLAV
TGDHPASTALPHAQPVFDLDSTRVAALARRAGLFVAVAEQPAAPPIDYRPVRLALKARAG
AELAILNLCGDLSDLVRFAGALAATGGAIPLVASVPVITSRSAALRLAALPGVRLPSGLV
TAVTAAAAVDDAGVHAAVAAAREALTVPGVVGVHLSAVVDETDPTGLAAVDAIVRTATLL
RASRAPSSDATATGAAA
>A0A2V2RGI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKILDFNERLKDSILIADGAMGSLLHESVGPQRCFDELNTLEPEAVFRVHQAYIEAGAQI
IETNTFGANRFKLAPLGLGDEVQKLNSRGVKIAREARESAAREVLIAGSIGPLGLGVQAR
HPEPDQILEIFREQAQALEERGVDLFVLETFTYIEEIMLAIDAIRSFSGMPIIASLTYAE
DCKAYGDLTPTQAAAQLKNKNVQVIGANCTLGPQALLPILQELASVDDLRVSGMPNAGFP
KREGDRIVYPKSSPEYFALFAREAAGAGVRILGGCCGTTPAHIRAMAEAVKSLKPAKHHA
SGAVVEASAKPVAVAQREPESKLWKSIQAGKFSVSVEIDPPKGIALDRIYEQVDKIMASG
KVDAIDINSGAMARVGMDALVVAGALEARGVETVPHLTTRDENIIGLQAGLLGAWTVGGV
RNVLAITGDPPSVGDYPETSGVYEVDSVGLVKVLSRLNQGTDWSGKTLGGATNFTIGVAV
NPVADDLDSEIERFQAKIEAGAHFAMTQPIFDPEHWHEFVKKLGGKPAIPILVGIWPLTS
YKQALRLNN
>A0A8G0PB03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma simmonsii|TrEMBL
MHIKSLVAETEKSKAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLEKVNDALQKAYKAGCTNILALRGDPPRDQES
WTAADGNFQYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGAGF
IVTQMFYDADNFIRWVGKVRERGITIPILPGIMPIATYASFLRRAKHMQCRVPPDWMAKL
EPVKNDDVAVREIGKTLVAELCKKLLANGIHHLHFYTMNLAQATRMVLDELNWTPSAENP
LKQALPWKQSKGFGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPASIQDIANTFVQYLEKKLETLPWSESGLAAEADPIKDDLVA
LNKRGLLTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLMPPYLLDEMISRLDDFP
NLTYYAVTKNGQLKSNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGVDW
AHCFDANTPSRALIEGIMNEWYLVNIVNNDFRENSTIFGFLEGLEVKDIAVPATPTA
>A0A2V8JFI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MQRNPLREALQSRRFSHVVEIVASRISREARLLEVASQLATTPGVVAGSITSYAGGAPGQ
DPLRVGTAARARGLTPNIHVTCVSKDRQELRQYLETIAGLGLENVFALTGDYPRGAAPVF
DLDSVQLITLMSELREQGMPLWIAAAVSPFKYTEPDCVYQYLKLEKKFAAGADYAITQLG
FDVRKFRELRQYLDERNLQKPVLGNVYVLGLKAAEKMSTGEPPGCWVAPELVETIQDEVK
AKDKGEAARLERAARMVAILRGLGYAGAYIGGTHNAQHVSWIIERGQILAPRWQVLLEEF
TYAPKSAFYMYEPRTDAHRKRLGFRDRAVNAFWHLLSPIQIPKGSVAEKWARAMFAWIDR
RSSMSHFLERAEFAIKSPAFGCQACGNCVLPDMQYVCPQMCPKQLRNGPCGGTNNGQCEV
ISEQSCIWVRVYERAKAADEIPLLKIYIPPPDRSLKGTSSWINYFLNRDSRPGRQGALPK
AAKRQQNLDQGVSPGLISQQNEPRTDGRCFKSAAPPGR
>A0A6L8GJ73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRRIPDIYAAGRTAGRPVISVEFFPPKTPQGDVSLFERVLPALAAVRPDFYSVTCGAGGV
GVRTRTLQIVDRMQREHAMTAMAHVTCVSFTHAEMDGFLDEAADLGIRNILALRGDPPAG
QPDFQRPAGGFDYAWQLIDVLKARADQFAIGCAGFPEGHPECREGREIDWQRLRDKVDHG
AEFILTQLFFDNAYYFEMADYLTGRLGVKVPITPGVLPILNARQIKRFTALCGATLPAPL
VAALDRFGDDDEAVARYGIEFATRQCEELLAAGAPGLHLYGLNRSRSAVAILRNLGLA
>A0A2N7PLJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldimicrobium thiodismutans|TrEMBL
MKTRFQELLERRDFVFTFELVPARSVRTRRYQEILKFLLESQKKNLFQAFSITDNAGGNP
ALSPIPLGKTIKNLGLEPIIHFSCKDKNRNQIESELLALDKEGLHNLLILTGDYPLQGYL
GRAKPVYDLDSVLLLSMISDMERGFDERPAIPFFKGAVVNPFKLTLPEIWWQYLKLYKKL
KAGAYFIITQVGFYPRKWLELKSLFDSGITFIFSRFLEDKELHLPEEDKKFKNVPLLGSL
LYLTPFLVKIIKEAKIPGILLTESILKRLEGSSNFEETVLDIAARFAAILKGLGYNGIHL
CGFPLDYSKIQLFFEKFSKYEASWEDYFEEFEGKAIFEIQGKVLKKDLPCLLKEDFDFSF
QGKYKFSFFMNEVFHNLFFNPQKTYFLYLKKFAQFIDQRPKLKRYFTSLEYFIKKLLFNC
QECGDCTLWEFNYKCPQSGCAKYLLNGPCGGSIKGFCEVYPFEKKCHFVKVFEESPSKEV
LKKFIRPGETFFIPPRNWDLFKTSSWLNFYLKRDHRSL
>A0A2V9KLL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MGTQLYAKGVFLNRSFDELNLSAPELVREVHEEYLRAGAEIVESNTFGANRIKLEPHGLA
ERVREINAAGVRIARDAASGAAYVGGSVGPLGIRIEPYGKTGIDEAREIFAEQIAALVEA
GVDLLCLETFSDLNEIRAAVAAAREFRLPIMAQMTLEEDGNSLEGTPPESFGPELERSGA
DVIGVNCGVGPQVMLEGVERLASSIRAKLVAQPNAGKPRSFEGRNIYLSSPEYMASYAKR
FVRAGVRVVGGCCGTTPAHIQAIGAAVRALRGAPPVVVTVVSPSAAAPEQAAPSSARSEL
ERRIEAKLPVAVVDLSPPTGGDPGEALEEVKLLVGRGVDAVKVSEAPRASAPMGALAFAA
LVQSQVGLEAILHYACRDRTLLQMQSELLGAHALGLRNFLLTTGEPLWIGDYIDATRVFD
VDSIGLTRLVAGLNRGRDIGGKAIPRPTRFFAGVFVDPGALGLDEEIRRFEYKVEAGARF
AITTAIFRPELLEQFLRRTRHCRIPVIAGILPLGGQGEAEFLNNEVPGMSIPEAMVARLQ
AAGSPEAGRRAGIEIARELVRQVRGMVEGVQVSVRGGRCSTALEILG
>A0A2E6NLJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MDGAMGTELYASGVFVNVSYDGLNLETPDVVETVHRNYVNAGAEVIETNTFGANPVKLSS
YGLADRTEEINHAAVDLARRSAQGRTLVVGAIGPLGIRIEPLGPTSREEAQEFYKRQVDG
LVEGGVDGFVLETFSDLNEMEQAFKAVRSRSPLPVICQVTVGDDACTSYGTSPEDVATEV
ASWGASVIGLNCSVGPAVMLEAVERMAEVTDLPLSAQPNAGLPRAVGDRKIYLASPKYMA
QYARRMIEAGARFVGGCCGTSPEHIRSIRALVGGVRPPSTRVRPGSHAESHDTPIQPEVP
LGERSVWGRQIAEGTFVTSVEVTPPKGWNAEILLGQCRRIQAAEANTVNVLDHPHAHTRM
SALPAAMLIEREVEIETIVHYPCRDRNMTRMISDLLGAAAAGLHNLLLVTGRPPAMGPYP
DSTASLDIDSIGLTNVVHGLNRGVDPGGNAIGVPTRFVIGVRVSQVAVDQDREAGRLNWK
VDAGADFVITRPVFDAERLHSFLEHVPELSVPIIASLRPLTSLREAEFLHNEIPGIQIPD
RVLARIANAEAHGEDAARAEGISIAMEAFAAVRDSIAGVHIHVADGNLDGALELLSEIRD
SA
>A0A6N9F6L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRRSELAAFLRERPRVGDGALGTALYAGGIASRRSFEDLNRSDPDRVRAVHTAHLAAGAE
VISTNTFGANPWKLGRHGLASEVAKINAAGARVARSAVRPGSLVLGSVGPSGEVVGPFDE
EKAPEFAAGFREQITALVESGVDAVLIETFTSLTEARLALSAAREVAPDIGVIVLMTFSE
QATTVFGVAADQAAGTLERDGADAVGSNCGVGPDTTLTALERMRDAVSLPLVAQPNAGIP
ERTEGRFLYPSSPDYVAHYAKRYLRLGVSLIGGCCGTGAEHIGAVAGVVRAASAGARADR
VRAPARPAAAAPAEEAPAEIPAVPVPERSGLARCLAEGRFAVSVEMDPPRGAEPGKFLAR
VGDLADAGIRFVNVADGPRATARMSAIAFAALLERSGEVETILHYQCRDRNLIGIQSDLL
GAHALGIRNLLAVTGDPPKLGDYPHATPVFDVDSIGLVRILRGLNHGLDLAGNPLGAALP
FHIGVGANPAAADLEGEMGKFERKVQAGAQYCLTQPVYETRLLERFVKDVRGYGIPVLAG
VLPLVSSRNAEFLHNEVPGMSVPQPVRERLATAPTRQRAREVGVSVARDMVAAARDLVAG
VYVMPPFNRFDLAIRSVTGLV
>B1I1G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforudis audaxviator (strain MP104C)|TrEMBL
MTTPSNLQRVLEQGHFAVTAEIGPPKGASGETVRRHAALLRDCTDAQNVTDNQSAVVHMC
SLAAAVHVLQAGGEPVFQLTTRDRNRLALQSDLLGAASLGIRNVLCLTGDHQKFGNHPQA
RGVFDLDSVQLVGLARRLCEGRFLNGDEVKPPPELFVGAVENPFAGPLPLRVLRLGKKIA
AGARFIQTQAVYDIELFARFMAAVREQGWDKEVSILAGVVPPKSAGALRYISKVPGMVVP
DKLIRRMKGAADQAREGKRFAVELIRHLRTIKGVRGVHIMAIRWEEAVPEIVTEAGLLPR
PHADKY
>A0A1G5H7R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. SF-50|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPGTIEHLMKYRPEYISCTYGAGGGNVGANRE
VCQMIRNAGTVPVTHFTVIKNTKEGIRQQLEQYLADGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A7Y3HA11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MKTFRQALHGKQFAISAELSLGRASTHQDIARQASIFRGRVDGVQIADNPLAWVHMSAVS
ASALVLREGLDPVPILTCRDRNRIALLSDLLGLRAMGVSSLLLMRGRRVPARHALHAST
>A0A7Y6BVV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus xylanilyticus|TrEMBL
MKADLRSVLQERVLIGDGAMGTYLYQMGFPVGISYEELNLVSPEVVADVHRRYLEAGTEI
FETNTYSANFDKLSKFGLESKVADVNRAGVRIAKDVAGANGYVLGAVGSIRGGKRTNVST
SELKRFYEQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDIGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGVPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFADLGARIIGGCCGTTPDHIAAIAQALTEYAPAPIAQPDPAE
AKPRIVLHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLDKAVQRLEKKIASGADYIMTQPVYDPQLIVAMHEATKHLEVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
DMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A0R2G277|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus mali|TrEMBL
MSTFNYSLELLQNNSNSKKQALKKLAPEFISIAYTNHTLSFFETTFSTALTLKKVTNIKT
AVHLPASSFTQEELDKLVVALQKSTIDSALILSGEKKLNKNSAYTSALELAKFLSRRIPN
LDILCSCHPETITSEINLQNELSLMKTKEAAGCKIFISQIFFDNTMFIHFVNHCRHAGIK
AQIRAGIMPIVNKNQLTFVKKILKLQLPDSFEQVSNDIELKKIGIQFALNQINMLKKQGI
TDFHFFTMDNLDTVKLLIDGVL
>A0A2V8LWU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKLRDLYARPGLTFSIEFFPPKTPEGDAALFREVEILKTLNPAFCSVTYGPSHHHPHPLN
IQLNRCGL
>A0A2V8M8P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRISQWSDPIPDLIIDQFSIPNSHPRHATRLWCMSLLKALHTSKRFLLNVEMCAPRMDLP
LQQSVDAWIDSNRLMRRITSRDRFVFMTDGAIGRREEPNLRHVVINLGAEADRSHIVPIL
TTKHSLDYCLQFAQRSYTLGFTSLVVLGGDKSDDTPRCVEHAYELRRLIRQKVPGLTLGG
WASPHGGRPQVDFMLHPEYSADFYLAQIVSHYQTRAIDEFVNETERLGVKIPGIFGVFYY
RSANPKTFAMLSKFIPVPAAELTRDFAADISPEEICARSIHALLQHGVKKVYVSNLPMAT
AAETFSRIEARVEEMLVVS
>A0A662E1X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKMTNVLSKAKNPVLSLEITPPDRGRSVDELFSAIEGLMDFAPKFISVTYHQPHTVYEEV
NGIIRRRPKRKKPGTVGISAAIKNRYGVTTIPHLICGGFDRFETEDALIDLHYLGMKNIL
ALRGDPAPGHTRFVAEKDGHHYASELVTQIAAMNRGEYLDELDNAVSTDFCIGVAGYPEK
HAEAPNLEKDLAFLKQKVDAGADFIITQMFFGFDYFCHFVEKAREIGITIPIIPGIKPVT
NRRQIEQIPRLFFATMPQELVKAVEGAKTPAEAFNGGTRYMAKLVQQLLDFGVPGIHLFI
QEKSDDSHALLSAVYGS
>A0A378VYD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae|TrEMBL
MVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVITQFFFDVERYLRF
RDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGLDDDQGTRNLVAA
SIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A2V8LQC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
ITQPVFDIQQLRDFLKRIEHCRIPIVAGIWPLVSFRNAEFLHNEVPGVHVTQEIMERMRD
ASAISKEAGRDEGLKIARESLLEVRDLIQGVQVSAPFGNVKYALEVFSVLPEFSSQQEAA
APAV
>A0A4Q3KBV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacteraceae bacterium|TrEMBL
MNQFTSRPPQPVEPEATLERWLTGPRFAPLPMRSAATPAPALSFEFFPPKNDALETQLWT
CIRRLEPLAPRFVSVTYGAGGTTQARTHSTVTRLVRETSLMPAAHLTCIGASRAEVDAVA
QDYWDCGVRHIVALRGDAPAGEAYAPHPDGYAYASDLVAGLKRIGDFEVSVAAYPETHPT
AQNADLDIDNLKRKLDAGATRAITQYFFDGEVFLRFLDRALAAGITAPIVPGIMPVTNYA
QAKKFSAMCGTSVPDWMGELFAGTENDPETRRMIAAIVAAEQVRLLQANGVDEFHFYTLN
RADLTYAIAHLLGVKPAVPAADTAGAAEKG
>A0A662DRG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKVTDHLDRATRPIISFEIIPPVRGGNFGDLTDLIEDLVRFEPPFIDITSHAAEAIYEET
SAGIKKKIKRKRPGTLGICALIQNKYNVDAVPHILCHGFTREETEDVLIEFRYLGIDNVL
AVRGDTLDYKKTIEGHRTINRWAGDLVRQIANMNRGAYLEDDLLDADASEFCIGVSGYPE
KHIEAPNLKTDLQRTKAKVDAGAEYIVTQMFFDNRHFFEYEKRCREIGIDVPIIPGLKIL
SSKSQLTSIPGTFHIDIPADLSDEVMAAKDAHVSGIGLDWTLRQAEELLSRKVPALHFFV
MQNSRTITKLLDRLQP
>A0A2E6ZSB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRLIRDIYAEAKAVDRPVMSIELFPPKTEKGNATLFDRTLPALQALGPDFYSVTYGAGGS
TRDKTLELADAIQRRHQTTTMAHLTCISTTLADIGRYLDDARSRGIRNILALRGDPPQAP
EEHRSSGTGFEYSYQLVEFIRERSGFSIGTAGFPESHIACTEGRHVDWQRLKAKIDHGAD
FVLTQLFFDNDDYFAFRDYLVGELGVDVPLTPGVLPILSREQITRFAALCGATLPSSLLS
TLESFGDDTAAVAHFGAEFASRQCEALLAGGAPGIHLYSLNRPEGATAIFEHLGLTDRS
>A0A1C5U5J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Blautia sp|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPVTIEHLMKYRPEYISCTYGAGGGNVGANRE
VCQMIRNAGTTPVTHFTVIKNTKEGIKEQLEQYLAEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A1H5LH04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruania alba|TrEMBL
MLPEALTSEALPPEALVSRWLRDPRYEVMPTDDVVDEVAAHLEAPATVTVTFSPTRSAAT
TVSIALRLAALGHRAVPHLAARRMRDRAELEDIAARLADGGINEVFVVGGDADSPTGAFS
SAIEVVRPLREISPGLSIGVAGYPESHPHIPDAAMHGALAEKAAYADRVVSQICFSPQTT
LRWACDVRARGIELDVLAGIAAPVPRGRLLRIATRIGVAQSARFLSGHPEMLRLGAGRYD
PGPLLWALAEAPTPISGIHIYTFNAMAAVQRWRRSLLDPAPEAA
>A0A0F4WGT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. IBUN22A|TrEMBL
MIKEFLNNNILICDGAMGTYYSEKTGNDISYCEFGNLNDKNTIRRIHEEYIEAGAKLIRT
NTFSANSKELGVSRKTLKDIIESGIEIAKEAVYNKEVFIGASIGPIRENGADENVVEVLE
EYKFIVDCFLDNNINVFIFETLSNLDYLEEVSTYIKNKKPESFILTQFAVKPDGFTRDGY
SVSKIVGEVKKINTIDSYGFNCGSGPTHALELIKKIDIGDDIVSSLPNAGFPEIIHERTV
YPNNPVYFARKVKEIKKLGVSIIGGCCGTNPSYISKLRDTIDNKPEPGDKIKRYEHETYN
EKNIIKNTFKEKVKNGDFVIAVELSAPVDTDINKIMTGAKVCKDNNIDIVTVPDSPMSKV
RADSVVMSSKIKREIGIEAMPHMCCRDKNTNAIRSSLIGGHIEEIRNILAITGDPISDAS
RIETKSVFNLNSFKLIELINDMNNEVFTSDDIFIGGALNLNVLNKEVEYGRMMKKVERGA
KFFLTQPIYDDSAVEFLKSIKERTDVKILGGILPVVSYRNAMFLNNELPGVTIPQEILNR
FSEDMNREEGQNIGIDIAVSMGKKLKGICDGLYFITPFGRVNMIVDIVNRIKEV
>A0A1F1PYJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. HMSC08G10|TrEMBL
MSQLKTALHDNTFVCILEFVPKSSSERFASIEALMVRQHLCGWPMTMAIADRVGSPFEMS
PLEAYSSFRQPLPALLHFSGKDRERHHLLEQLQQMDAAGLDQLLLLTGDRLPGHVPGQRP
VRYLESIAALQTVRQARPDWLLGAGMHPFKYREEEGGAQYFKAEKKLAAGADFLALQLGY
DASKHLEAIQWMRRQPHPKPLTACVMGLTLGRAKIFEHVAGIVVTPSMHDVLAAEAAVSK
AHAQARSLERLALQIIGLRLMGYAGIHLSGIHDLEQLDTLERSLEHWQARLHSLEQWTPA
WQACWQMPGLPDVTFHPPGANWRLGESQVSASPKETARYHLLHGLHSLLFSRRHPLSQAF
GWAVQRPLWNTPTGARVLHRLERSAKRPLVGCDTCGTCRLEDTLYICPETCPKGLANGPC
GGTTLNRCEFGDRECIHSVKYRTAKAVGQTAVLTERLIPCIDADTRHRSSWPTWFQAPAA
TTTIAKPCGSGLAPQSVTEPEPKAPALHASKVPELDN
>A0A7X5KNA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerotalea alkaliphila|TrEMBL
MLKHKLETKAFGILTYGITPPKSSNPEEKIREITARHIGRIRNLDIDGLILYDIQDESDR
THEKRTFDFIRTVDPSVYSREYLKELKVPRIVYRCVGNYEPQELGEWLEEGKDEVAVFVG
AASRNQVVKMRLQEAYAIHREKGDKVLLGGVTIPERHLKKKDEPERIGFKYQEGCRFFVS
QAVYNVEGAKAFLKDYAAYCKKHGIEMVPILFTLTPCGSERTLQFIKWLGISVPAHLEEA
LLQSGDHMLQKSMELSLGIFKELTKFALEHQIPIGCNVESVSIRKEEIEASIRLTREIKA
FIEEVRAERL
>A0A828U8M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium acnes PRP-38|TrEMBL
MAPDFISVAYGANGSRCDRALRCTQHMVSTGLRTVGHLTCVAQSVADVEQMVADYAESRI
DHILAIRGDMLGGAGQPWVAHPWGLPNATELVRLVKWVHPEACIGREGA
>A0A416KNU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. AF28-13AC|TrEMBL
MNDIREFLSRRPLLFDGGMGTYYKAAPGIECERANQTDPAGVQAVHREYLEAGADAIKTN
TFGLPRMAAAHTPGWEALAEAGWKLAEAAAAPAGAFVFADLGPAPETEALPAAQVYTAVA
EQFRKLGAKNFLFETLSSDAGILEAVRTLKAAEPDTFVLVSFAVLPDGYTREGLYCKDLV
RRMSESGCVDAVGLNCVSAPGAMRTLARSLSSALPLSVMPNAGYPVVTRTQVRYQGKPEY
FAQELSGLAADGVVRILGGCCGTTPAHIAALRAALDALPETAAPARTKEFSTPEAKPVEN
EDAFLCKLNAGEKVIAIELDSPRNADLTAYLEGARKLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGMCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSAMTVFGALNLNARNFEVELRRAGEKLEHGMSGFL
TQPVLSGQAVENLRHAREVLGSRARILAGIMPVVSQRNAVFMENEINGIHVEEDIIRQFA
GLDRAQGEELGLAISLKMAREALPYADGFYLMTPFNRVALMERLIARLRTEVLQES
>A0A6S7CMF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter dolens|TrEMBL
MSALKQALNARRFACVLEIIPQQSPARRAALERIVQRGHLAGWPLLPAFADRVGLHSDLS
PLQGAGALGDPASSLLHFSGKDRARADLLGQMDAMQARGLSQLLLLSGDRLPGHDPGRAP
VRYLESVPALQIAREHGPDWLLGAALNPFKYREEEGAAQYLKAQKKLLAGADFLTLQLGF
DAAKHLEAQAWMRAQGCVKPMLACVMRLTHRRAAALQDVPGIVITDAMRELLGREQEISP
ADASARSLERLALQIVGLQWMGYAGVHLSGVHTLDELLLLEQAIAEQRDAVTSLSDWMDR
WQASWRMPGIPQTGFAPGIDAWELGQSDVAATPGERLRYTLLSTVHEQLFDRTGWLGSAF
GWSVTRPFWKTGVAARALLAVERTFKRPLVGCDTCGTCRLQDTLYVCPETCPKGLANGPC
GGTRLNRCEFGDRECVHSVKYRIAKSADRLPALAQTLIPCIEAGDRHRSSWPEWFKLEDP
TRGNDCQSLPKSG
>A0A844ZJ90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteraurantiacibacter aestuarii|TrEMBL
MSYSAIHPNWEKPADNMVDGYSLEMTAKEIEGLKEAAPLIRPGTQVAVTFLPGEELEQRV
EAAVLVRELGFEPIVHLSARRIESEQQLDWYLGEITQKAGVKRVFIIAGDPPEAEGPYSD
SLQIIETGLLEKHGIEIVGVGGHPEGHPNNTAAQLWDWMERKIAAVRAHGMTPLVVTQFA
FDDDAIVAWLAEMRERGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGVSLTN
LIGRAGPDKLVDSLNSKLGEAHGRVRLHFYPFGALTASAEWINEYHAKHS
>A0A014EK64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_1|TrEMBL
MKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGKARDIQDFEQFLEQA
QTANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGVRIGGAFNPFKYVE
AERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKAFLTKNNYSQQILACVMPLTLGRA
NFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKHLGFAGIHLSACHKP
EEQMLLESYIEQYRHLELNVLEELWNSLWQVTTGKEFSPEIVRFSRQPTSKQLIKYRQLH
VMHEAMFGSKIAKGVGRFIFKASFWENALIAKLLLKTEVLSKHSLVGCESCGQCRLGDTL
YICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVEQTEILKDKLIPTVSIE
TRGTSSWKNWYLGAEA
>M0L2L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula japonica (strain ATCC 49778 / DSM 6131 / JCM 7785 / NBRC 101032 / NCIMB 13157 / TR-1)|TrEMBL
MALGTRTVSDSQGVRTLLTSARFELMPFESFDEEITHLPDDATIAITTSPQLGIEKTVEK
TEEAAEVGFDVVPHIAARYVEDREQLEAIAERLEQAGITDIFVPGGDREEPAGEYESALD
MLEALAETEYSFEEVGITGYPEGHDFIDDETLAESMAQKAPYATYIVTQLCYDPDAVLEW
VEDIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDDEYNIRGVHIYTFNQTPDTEKWRHNRLDS
>C7X8N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. D13|TrEMBL
MKVIDLIRDSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A0F7PHV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea sp. IMCC20628|TrEMBL
MSMSDVNPAGIDLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRIGYAPIMQIACRDRNRIAIQGDVLGGAAMG
VGNILCLTGDGVQTGDQPGAKPVFDLDCMSLLETIRIMRDNGKFLSGRKLTTPPQVFLGA
AINPFAPPHDFRPHRLAKKIAAGAQFVQSQYCFDVPMFRAYMQTVRELGLTDDCFILCGV
GPLASARTAKWMRANVPGVHIPDHVIARLEGATDQKAEGKQICIDIINEVKEIDGVSGIH
VMAYRQEEFVAEIVHDSGVLKGRKPWRKEPNPANERAESLLEEAPDHSRLTPHVMAGVAA
DSGD
>A0A1M5FEN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbulbifer donghaiensis|TrEMBL
MTDSIRISFEFFPPKTPEGRDKLYKTREALQEFQPEFFSVTYGAGGTTRDTTANIVTGLR
RDGISIAPHLSFGGDNEEIILDLLNQYRDAGVDRIVALRGDMPSGMGAVAQLVYANELVA
FIRRHTGDQFHLEVAAYPEIHPEAESYDDDIRYLKGKFEAGANSALTQYFFNPDAYFYFI
DQCEKAGIDAPIYPGIMPIINFANLARFSRNCGAEIPRWLRHRMESYQNPEDIKKLGLEV
VTDLCETLLEGGAPGLHFYTMNQVEPNTTILQNLGIGN
>A0A412F3C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFKYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVEGVHLYTMNNAETARHIHEATHSLFKHHSQVGAL
>A0A369Z7P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aggregatibacter aphrophilus|TrEMBL
MSYAKEIDNLNQHLANLNGKINVSFEFFPPKNEKMENLLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLEAAPHLTGIDATPDELRQIAKDYWDSGIRRIVALRGDEP
PGYSKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMASVTNVSIPAWMAKMYEGL
DDDQTTRNLVAASIAIDMVRVLSREGVKDFHFYTLNRSELTYAICHILGIRPTL
>A0A2T2V0P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium SW_11_64_17|TrEMBL
MKVTKHFDQASEPLISYEIIPPKRGGSAEQMLEVVEELMPFDPPFIDVTSHSAEVEYKQK
DDGAWERCVKRKRPGTIGLCAAIEARFGIDTVPHLLCKGFTCEETEDALIELNYLGIDNV
LAIRGDDNGYEKSISGNRSRNEYAADLVQQIQDMNQGVYLEDLMNAEPTDFCVGVGGYPE
THFEAPNLAWDIMRLKEKVDAGADYVVTQMFFDNEYFFRFVDKCREVGIDVPIVPGIKIM
KRKRHLRTLPKYFHTEIPEELAAEIDAADPEDVEKIGVDWAIRQAHELMEADVPCIHFYI
MSSADTVKKVVEPLREPKEVA
>A0A1S2UXD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas costantinii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKIPAAPHLSCVGDSKDDLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VAFIREESGDHFHIEVAAYPEMHPQARNFEDDLKNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCDRLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2V2SY84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. RW407|TrEMBL
MSSQERRFSFEFFPAKTEAGHEKLLATARQLAGYKPDFFSCTYGAGGSTRDRTLVTVLQL
DGEVGIPTAPHLSCVGDTKAELRALLAHYKDAGIQRIVALRGDLPSGMGMASGELRYANE
LVEFIRAESGDHFHIEVAAYPEVHPQARNSEHDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAQKLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIASIQSF
GEQVITEMCERLLDGGAPGLHFYTLNQADPSLALWKNLKLPR
>A0A495DSY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter vaceletii|TrEMBL
MKVTDHIKKANGETLFSFEIVPPVKGKNIQQLYDNIDPLMEFNPPFIDVTTSREEYVYIK
KSGLLDKQITRMRPGTVGICASLKHKYNVDTVPHVLCGGFTKEETEYMLVDCQYLGIDNI
MALRGDAMREEQYFTPTKGGHPYAASLVSQIQNLNTGKYLHDDTPMENNANFCIGVAGYP
EKHLEAPSLQSDLKRLKEKVDAGADYVVTQMFFDNQKYFQFVEAAKEIGINVPIIPGIKP
IAVKRHLQLLPQVFKIDLPQDLIDAVDGCENNKAVRQVGIEWAIQQSKELKEAGVPVLHY
YSMGKSDNVYSIAKTLF
>A0A1H1FYH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tsukamurella pulmonis|TrEMBL
MTEQSRTVLDRLDAVRASGRMPFSVEFMPPRDEEGEARLWRAVRTFERMDPAFVSMTYGA
GGSTRDRTVRVTGEIAASTTLLPVAHLTAVNHSIAELRALMGSYADQDVRNVLVLRGDPP
GDPLGKWVRHPQGLKYASEVVELVRELGDFHVGVAAFPEGHHRSPNRESDVRYFANKLRA
GADYSITQMFFDVDDYLRLRDEVAAFDPEQGAKPLIPGIMPITSLKSVSRMAELSNAKIP
DAMRAELRAAAGDGPEENRAAVRAVGIEIATRMGERLIAEGAPALHFCTLNFAKATSEVL
ENLGMMPVGV
>A0A413ABL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLNAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHEATHSLFKHHSQVSAL
>A0A6A6NKL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hevea brasiliensis|TrEMBL
MKVIDKINAAIGGAGLPEVNANGGGDPNNNRVVFSFEFFPPKTEDGVDNLFERMDRMVSH
NPSFCDITWGAGGSTADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKSNGI
QNVLALRGDPPHGQDKFVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDMIGSD
GVATPENYQKDLEYLKRKVDAGADLIITQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPI
YNYKGFLRMTGFCKIKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAYGIKTLHL
YTLNMEKSALAILMNLGLIDESKITRSLPWRRPTNVFRAKEDVRPIFWANRPKSYISRTL
GWDQYPHGRWQDSCNPSYGALTDYQFMRARARDKKLHDEWATPLNSIEDILEKFKKHCLG
KLKGSPWSELDGLQPETKIINEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYV
YQKAYLEFFCSTDKLQVLVDKCKSFPLVTYMAVNKGGTLVSNVGPNDVNVVTWGVFPAKQ
IIQPTVVDPASFNVWKDEAFEIWSRGWASLYPEDDPSRKLLEEVQSSYFLVSLVDNDYIH
GDIFAVFADL
>A0A7W7S082|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium album|TrEMBL
MALGRPSVLPDRVPTVREILAAGGRSFSFEFMPPKTDEGERQLWRAIRELEALRPSFVSV
TYGAGGGTRDRTVEIVERLAHETTLTPVAHFTAVNHSIRELRHLVGRFADAGVRNILAVR
GDPPGDPMGEWVRHPEGVLYADDLVRLIRQAGDFCVGVAAFPYKHPRSGSVEADTEHFVR
KCRAGADYAITQMFFQADDYLRLRDRVAARGCDTPIIPGIMPVTQLSTIARSEQLSGAPF
PADVAARFEAVADDPAAVRRLGIEHAAELCQTLLDEGVPGIHFITFNRSSATREVFQALD
VAPKAAFLPA
>A0A7X9BWA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfitobacterium sp|TrEMBL
MENSFNKENTSFKNSILDKNTFSTTWELVPGRGAFERSQEAALLAAEQAAKGGKVHALTI
TDNPGGNPAILADFLGQEIIKMGIEPLIHFTCKDKNRNQLESQLYALDRAGIRNLLVMTG
DYPRTGFAGRPKPVFDLDPTHLLRIIGEMNQGLEVKTPKGTAQHKASDFFAGAVVSPFKT
LEAEQMAQYFKLKKKIESGAQFIVTQLGYDARKFHEVLQFMKLHEYDIPVVGNIYVLSYG
AAKLMSQNKMPGCVVTDKLVAELDKERNSPDKGREARLLRAAKMYAFMKGMGFAGVQIGG
HNLKYEEVEYIIEKGEELTANWQDLIPEFDYPIPDGFYYFEKDEKTGLNTDKPVDRDDIP
LASPVGFQFWSMWQMHKLAFTPDVGLFKTMQKIYTHKNPKRYPFEHFIKALIYDCKDCGD
CALLDLAYLCPMSQCPKYLRNGQCGGSYKGWCEVYPNERQCIYVRVFSRLKKYREEEQLD
SYQIPPANWDLFQTSSWYNYYLGRDHSALTLGIRPPEGFQGEGMQ
>A0A5B7XAM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter cryaerophilus ATCC 43158|TrEMBL
MFETLISKLQEDKYLTLETTPQHEPSMHNIVEKIKKFKIDSKVDGFTCTDNPLAKLKYNS
LFAALKLQQEFKKPVIATMTMRDRNKIALQSDLLGANDFDIRAILAITGDPANMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFAVVNAYAKNFGSLEKKMHLKI
QNGAVGIITQPVFDIENVKKLLGNFENAKENVEGDKRKAQLILGVFPITKLRTALFLSAQ
VPGIHVPQFWIDELERAHSISEEEEYKVGMQLSRNLFQEINKIHPKIHLMTANNKFEVAS
EILD
>A0A6N3BAL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus simulans|TrEMBL
MSRFLQTLSKNVLVADGAIGTILYSEGIDTCPEAYNLTHPKKIEQIHRSYIEAGADVIQT
NTYGANFEKLQAFGLEHQVRDITRAGVRIAKQAANEDTFILGTVGGFKGVKQNDLSLSTI
LYHTDIQIETLIDEGVDALLFETYYDLNELLQVIRATKKKYNIPVIAQLTASSTNYLQDG
TEINEALKQVEAEGADVIGLNCHHGPHHMQQSFTHIEIPQHAILSCYPNASLLDFEDSTI
HYSDNASYFGKIAETLVKEGVHLIGGCCGTTPEHIRFIKQAVEGLKPTLEKKVIPIRRKS
NYPSIPVKKNNLTTKVKAGPTVIVELDTPKHLDTTKFFANVTKLDKAKVDAITLADNSLA
TVRVSNIAAASIIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKV
GHLPGATNVYDVNSRGLTELAVRFNQGLNIDGGALKTKTNFNIAGAFNPNVRKMEAAVKR
LDKKVDCGMSYFITQPVYTVERIQEIAEKTAHLDTPFFIGIMPITSYRNATFLHNEVPGI
SLPDEILDQFEAVKDDKQKTKELSLRICRNLIDEIIKHFNGLYIITPFEQVDFSLELTHY
FKKQTEKNQEAII
>A0A481Z7G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pithovirus LCPAC304|TrEMBL
MSITIPKTIFGVVPPPNTLKYTSVERYVKRLADTYRDLEPDAMIIYDIQEEKGRNGKERP
FPFRTRFSPLAFHDLLFKALPEDAVLILYQTLTVDKPLSDLSEYIQECREKHHIQYLVWV
GASKAISVMDASRLTKRGCPEITIGGITIPERHRDRHDEDQRVLDKINSGIDFFTSQIVY
NADNVITFLKDYWRMCQTYAISPRTIVLAFAPFGRQDTLEFMRWLGVEIADGTANRVLSR
DDVRQRIDESIEICLEIFTTVQAMCTRNNMDIPLGITVESVSKYKDEQKGASTLFVLLKK
ELSV
>A0A0D1L8B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis|TrEMBL
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLIIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTRAKEFIS
VHHERTEPGLDEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPVYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMARAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>A0A8F9SU14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis|TrEMBL
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAHEVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLVPITEKEVKTRAKEFIS
VHHERTEPGLDEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALIKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMAHAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>A0A1G9IHD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas indica|TrEMBL
MSQERRYSFEFFPAKTEAGHEKLLATARLLAGYKPDFFSCTYGAGGSTRDRTLNTVLQLD
SEVKVPTAPHLSCVGDSKAELRELLARYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGEHFHIEVAAYPEVHPQARNFESDLANFVRKAKAGASSAITQYFFNADSYFY
FVERVRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIDSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3C0FB97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium UBA8153|TrEMBL
MKSGSRLERLFAAGHFVCTGEVGPPKSASSRSISRHAAHLRDAVDAVNLTDNQTAIVRLS
SIAAGVHVLGEGVEPIIQMTCRDRNRIALQSDLLGAYSLGLRNVLCLSGDHQAFGNHPAS
RNVFDVDSIQLIKLVKDLRDEKKFQSGEACRVEPRMYIGAAANPFADPFEFRVVRLAKKV
AAGADFIQTQAIFDLERFKRWMGMVRDRGLHEQVHIMGGIVPVKSAVALERTGEVAGMVV
PPELFKRMQGAPKGKQQEEGINIAVELIEEIRQIPGVRGVHIMAIAWEEMVPEIVERAGL
LPRPQLEETGPQARE
>A0A1C0SKM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. LC14|TrEMBL
MTAQTLYPAERGNLRLSFEYFPPKTDEMEAQLFQTAEDLAVFGPAFVTVTYGAGGSTKAR
SLTTVRRMIEEKGFANTAAHLTCVGAPKAEVDAVIDEYIHCGVRHFVALRGDPQGGIGSV
YQPHAGGYDSSADLVRAIRARGDDIEISVSSYPEKHPESPDVAADIDMLKRKVDAGANRA
LTQFFFDNNDYERYLEQVRRAGIDIPIVPGILPINNLTQVQKFAGLCGASVPEAIVTRLA
HLEDQPVERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLVTAVLDLVGFEQVVLDAG
DALHEAPQKKVAGAAA
>A0A508W8E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc pseudomesenteroides|TrEMBL
MTKINQIYKTKPVPVLSFEVYPPHQEESVKSLFQTLEELNPRQAGVDFISVTYGAGGSAN
HELTQHIASYIQNHFGVTALHHLTGINQTPATLHHNLSEMKAAGIENILAVRGDLPSSDY
DNSCYPFAKDLITDIKKENDFSIGAAVYPEGHVDNPITGISVGGVREKISAGSQFLISQL
FFDNNAFYKMQEELKNNYIQIPVSAGILPIISQKQVEKLTYMIGSSLPAKLAKIVHKYQD
NPEALRQAGMAYAMEQIYDLLDHGVDGIHLYAMNQADILTTMLPKINDYIQCKNKRYAV
>A0A2X5NX97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tatumella ptyseos|TrEMBL
MYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLLSLKRKVDAGADRAITQFFFDVE
SYLRFRDRCAATGIDVEIVPGILPVSNFKQLQRFATLTNVRVPNWMNTMFDGLDNDPETR
KLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPQLAAV
>A0A315B136|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. MMS-10A-178|TrEMBL
MKKLPVSFEFFPPKTPEGAEKLRVVRQQLYTQAPEFCSVTYGAGGSTQEGTFGTVGEILK
EGVDAASHFSCIGASEESVRNELATLKAMGVKRLVALRGDLPSGYGMGGAFHYASDLVAF
IRKETGDYFHIEVAAYPEIHPQAKSAESDLQAYVSKVKAGANSAITQYFYNSDAYFRFVD
DAHKLGADVPVVPGIMPIGSSTQLLRFSDACGAEIPRWIRLRLQGYGDDTASIKAFGLDV
VADLCDQLRNAGVPALHFYTMNQSATTLELLKRLA
>A0A174FWV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium symbiosum|TrEMBL
MKIKDILAAGSPTLSFEVFPPKGEEAYESVEKAALEIAKLKPAFMSVTYGAGGGTSRYTV
GIASDIQRETGVNTLAHLTCVSSTRSEVKSVLKQLREKQIENVLALRGDIPADGPIATDY
RYASELIYDIKQFDENLCIGAACYPEGHVESVNKTADIEHLRDKVEAGCDFVTTQMFFDN
NILYNYLYRIRERGITVPVVAGIMPVTNVKQIKRICQMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAKIGDSLSEIL
>A0A0J7XPZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium czechense LL01|TrEMBL
MPVIHPNWERPPVNMVDGYSLEMTAKDVESLREAAPSIAAETPVAVTFLPGEDFAARIAA
TKLVRSLGFEPMPHFSARRITSTGEFENYLAAAVAEADVRRCFVIAGDPSQPEGPYADSS
ALIGSGAFERAGIRAIGIGGHPEGHPNMTPDQCWSVLLDKCTEIERRGMAPLIVTQFVFD
ADAVLVWLTELRARGIEAPVRIGVPGPAGIKTLMRFAARCGVGASASVLAKYGISITKLL
GTAGPDKLVETFERSLGEEHGRIRLHFYPFGGLEKTVAWINDYARAH
>A0A3S3N1P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cinnamomum micranthum f. kanehirae|TrEMBL
MKVIEKIRAASEEGKVVFSFEFFPPKTEDGVDNLFDRMERMVSHNPSFCDITWGAGGSTA
DLTLDISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVEHIRAKYGDYFGITVAGYPEAHPDMIQGEGGVSLEGYQNDLAYLK
RKVDAGADLIITQLFYDTDIYLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPLEIIAALDPIKDNEEAVKAYGVHLGTEMCKKILAQGIKTLHLYTLNMEKSALAILKNL
GLIDDAKISRSLPWRRPANIFRVKEDVRPIFWANRPKSYISRTHGWDQYPRGRWGDSGNP
SYGALSDYQFMRPRSRDQKLQEEWAVPLKSVEDVHEIFMNFCLGKLKSSPWSELDGLQPE
TKIINEQLGNVNMKGFLTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSKEKLN
VLVENCTAFPSLTYIAVNKDGLYLSNVGLNAVNAVTWGVFPAKEIIQPTVVDPASFMVWK
DEAFEIWTRGWACLFPEGNPSRKILEQVQSSYFLVSLVDNDYIHGDLFEVFKDI
>A0A5R9R167|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas nicosulfuronedens|TrEMBL
MSQKERRFSFEFFPAKTEAGHEKLLATASQLAAKKPDFFSCTYGAGGSTRDRTLTTVLQL
DGEVKVPTAPHLSCVGDTKPELRALLAHYKDAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRAETGDHFHIEVAAYPEVHPQARNFEDDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAEKLGVSIPVVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDIASIQAF
GEQVITDMCERLLEGGAPGLHFYTLNQAEPSLALWNNLKLPR
>A0A258CLJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium 32-61-5|TrEMBL
MTSANRPSISFEFFPTKTDAGHEKLLVTAGRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGDIKVPTAPHLSCVGDSKSELRELLNTYKDAGIRRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKARAGADSAITQYFFNADCY
FYFVERVRKLGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMDSIQA
FGTQVISDMCEKLLAGGAPGLHFYTLNQAEPSLAVWENLKLAR
>A0A6P1C162|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium tropici|TrEMBL
MSSRSESHNAGIRISFEFFPPKSEEAEQQLWNTVEELSDWDPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLATGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVGALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKAKNGADRALTQF
FFDNDAFERYHDRVRAAGIEIPVVPGIMPIQNLTQLKRFAGACGASIPSWLDERFDGLDD
NIEERAKVAADVAAEQIQDLVGRGIHEFHIYTMNRSPLVSAVLERLGLQRKVASRAGAAA
>A0A6I7FA97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. NSP9.1|TrEMBL
MGFLDDIKHNILIADGAMGTLLYSYGIDRCFEELNISKPDEVKRVHEAYVQAGADIIQTN
TYGANFIKLSRYGLEDETKQINEKAVRIARSAAGSAYVFGTLGGIRTFNKNTYSLDDIKR
SFREQLYLLLNEEPDGLLLETYYDLEEAREVLKIARKETDLPIVLNVSMHEEGVLQDGTP
LSDSLKLLADLGADVVGINCRLGPHHMIKALEEVPLLENAYLSVYPNSSLPSLVEGRLVY
ETDDQYFRDSAKEFRNQGARIIGGCCGTTPHHIRAMAEAVKDLPPVTEKHVKIKKQAQAA
VQQERTEPALDELAKEKRSIIVELDPPKQLNFEKFLRAAEELKAAGIDALTLADNSLATP
RISNVACGALLKQRLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLIGLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRIE
KKIDCGADYFISQPVYSEEQLIKIHEETKHLETPIYIGVMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGNDKQKQTQEGLAIARSLLDAACDLFNGIYLITPFLRSDLTAELTAYIH
QKEKETANVYHQ
>A0A7Y5XFM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomycetaceae bacterium|TrEMBL
MDLQQRIRDHAGEFLFFAVTPPRQTTTPERAQEIADITRKRLDGLKPDGLVLYDIDDESD
RNPAERPFPFTPTMDPAEYLARHFGALDLPVVVYRAVGKYDESDFRSWLTAQPDQALSVF
VGAASRETRVATTLSRAQSLRAELRPDLLLGGVAIPERHRRSGTEHLRLLAKQETGCSYF
VTQVVYDVNAAKDLVSDYRYECAARGLAPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWIR
NELQHADDTLEASFEHALATARELMTFCRRLEVPFGLNVESVSIRREEIEAAFDLAARLR
SELCR
>A0A7K4Q4M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melospiza melodia|TrEMBL
MVNEAQQSCSGSSSSRSDGGSSSGSESSKDSSRCSTPVLDAERHERLRDKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRRVLRAGGPLFIDVTWHPAGDPGSDKETSSMIIAYTAVNY
CGLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVYAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVRALLKVLRKYELRVNYH
IVNVKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A854GLU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio vulnificus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSTPQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAQTGLVAAPHLTCIDASREELINIANDYWANGIKNIVALRGD
IPPGGGAPDMYASDLVTLLKSLHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQASRFAAQNNVKVPGWMAKQFE
GLDDDPVTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKKA
>A0A520PQ71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterales bacterium|TrEMBL
MEYQSLLHKKLKAGGFVFTAETTPPDASDKEILLEKTKPLKGIADAINVTDSPGAKVHMS
ALTAAIILAQNNIDPILQLTVRDRNRLALQGDLVGASALGVHNVLCLSGDDPKGGDQPET
KSVFDIDSLTLVATAEMMRKEKKFPSGRPIDPAPKLFIGGAEVPSKGLPDTKKITNKINT
GVNFFQTQYVFETKKLKEYMKVLEDSGILEKTYFLIGLGPFASAKSAKWMNDNLFGVDVP
DEIVNRLEQAKNAKDESKKICLELIEAFKEIKGVNGVHLMGHKKEEVIAEIIKESKIS
>A0A362X0Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jejuia pallidilutea|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPKKGKNIQDLYNNIDPLMEFKPPFIDVTTSREEYVYID
RGNGLLDKRITRMRPGTVGICASIMHKYNVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKEEAYFKPCEGGHAYASELVAQIAKLNRGKYLHDDVVVESNSDFCIGVAGY
PEKHMEAPSLITDLKRLKAKVDAGADYVVTQMFFDNSKYFEFVKKAREIGIDVPIIPGIK
PIAVKRHLQLLPQVFKIDLPQDLIDAVEACKDNKAVRQVGIEFAIQQSKELLDFGVPVLH
YYSMGKSDNIKAVAEALF
>A0A239BGM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus saharensis|TrEMBL
MTASVRELLATSRPTWSFEFFPAKTPEGEAQLWTALRRLESLRPSFVSVTYGAGGSTREG
TVAVTERIAAETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WVRHPQGLEYASELVELIRSMGDFSVGVAAFPERHPRSPDFDTDVEMFVRKCRAGADFAI
TQMFFRVEDYLRLRDRVAARDCDVPVIAGVMPVTNVRQITRIVQLSGQAFPEDLAARFAE
LDGDRPEDKAAVRAFGVEVATAMCRRLLDEGVPGIHFITMNRSTATREVYANLTDRGTGT
SVPSTLAAST
>A0A261F8N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium tissieri|TrEMBL
MHKPIFSLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTQSDRTATARIAHTIR
AEYGIPTVAHLTALYADYEVVDRALDMFDEAGVTAVLALRGDELPDHETVGVFPHASDLV
AYIRERRPELKIFGACYPEGHYQAESLDQDIENLKIKVDAGASHLISQLFYDNEDFYRFL
DKARAAGIEVPIEAGIMPVRGAKSVRRMAERNASRIPKGLETILDRWEGNRDALHAAGIA
YASQQINDLVAHGVDGIHLYSMNHPGTTRRIWNNVKPLFQEV
>A0A0Q7DSD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp. Root413D1|TrEMBL
MRPDVRPNFQVSFEFFPPKTDVMEERFWDSIHKLAPLHPRFVSVTYGAGGSTRERTLRMV
SRVKADTGVDAAAHLTCVGATRDEVDTVVRGYQEAGISRIVALRGDPAEGIGKPFTPHPE
GYKNAADLVAGIRRIGEFDISVAAYPEKHPQSPSWEADIDNLKRKLDAGATRAITQMFFD
NDDYFRFVERARAAGITAPIVPGIQPIHSFKQISGFAARCGASIPGWVAERFEGLEEDPE
THALVASAVAAEQVLELVDNGITEFHFYTLNRSNLVLALARLLGARPD
>A0A432STA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp|TrEMBL
MFKKFCQTLHSDKPFITVEITPPHGASLKSTIENIKTFNLQERVAGFSVTDNPLAKLKMS
GVLSAIQIQQAFKKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKFSDQPE
VKGVLERDSTLLLSIIYRLNNGFDYSNKELNPKPKPIYPFAVSNAYAKDMRRIKKKMLKK
LNYGARGIITQPVYDIDNAKELIEIFEECKHESVRETAKNAKLILGQFPVVRAKTANFIS
DKVPGITVPKEIIDEMDLAAMDGIEKEQEVGFSISKSLFDDIIKLHPKIHLMTHNRFDLC
SELIGNN
>A0A0M2R2B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiloniella litopenaei|TrEMBL
MKRPDISFELFPPTSANGLDNLTKTVTRLKAFEPKYYSITYGAGGSGQQKSKNLLEQLSQ
DKDLTLAAHITMSGASKADILETVKGWRDLGVTRLVALRGDAEEPGAAFKPHENGFRDSV
EFIASLRELGDFDIAVAAYPDPHPDSKSLADDLAFLKQKQDAGATTAITQFFFEAECYFR
FVEAARKAGITIPIIPGILPINNITQLQRFADRCGATIPDWVSKAFEGLDDNPETAAAVA
VSLCLDLCRDLIDGGVNAFHFYTLNRSPLTEAVCRLLSIQAEEKEAA
>I2J0D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. SK643|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETISDLDKVGVQKILALRGDIIPDVEPQKDFHYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A429SW78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC05374|TrEMBL
NAHFPAALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIY
ENLGLHHPPQA
>A0A8B9DXQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anser cygnoid|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
IELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTELEGSFCRMER
R
>A0A7V7AZP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacteriales bacterium|TrEMBL
MAPNSAESILDRIEESTAGRIPFSVEFFPARTPEAQERQWRSVKTYEKWGACFASVTYGA
GGSNRDRMLDITKRIYDETTLLPLAHLTAVNHSRNELDRILDSFAQAGIHNVLALRGDPP
GDPLGIWRKHPKGVEFASELVSIIADRGDFHIGVAAFPNGHFRAPTIEADTHYTLQKYKA
GASFAITQIFFEPEAYLRLRDRLVAAGRELGNRPLIPSIMPITSLRSAQRMVELSGARLP
RWLEQRLDAAAGNSSEEDVAAVTELGIELAIDMCETLIKEGVPSLHFDTLNKTQPVGRVL
EGLGLIESSSEDL
>A0A243IJM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis subsp. konkukian|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAYVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPDVVRERMDGHETKEAAIEEGVRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A848R1D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIKAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVNAVNSVKEVAKAIY
>A0A8I1V9X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp|TrEMBL
MNAAHAQGTGFPVSFEFFPPKTPEGADKLRVARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILSEGVGAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPDADLQAYVTKVRAGADSAITQYFYNSD
AYFRFVEDAHRLGADVPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASI
KAFGLDVVTDLCDQLRTAGVPALHFYTMNQSAATLEICRRLGI
>A0A222EZP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania flava|TrEMBL
MREAQRALETPLFSGLPGDIEVSFEFFPPKNEKMGETLWRSVETLAPLGPRFASVTYGAG
GSTRERTHQQVVRIQNEANIPAAAHLTCVEATRDQVDEVARHYWDEGIRHIVALRGDAPD
GQGTYRPHPDGYGNAVELIAGLKRVADFEISVAAYPEVHPDSPDRQADLDNLKAKFDAGA
TRAITQFFFDPECFFDFRDRAAAACIEGEIVPGIMPVLSFAAVQRMSGLCGTAIPDWMEG
LFDGLDDRPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKVA
A
>A0A1G3E7F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium RIFCSPHIGHO2_02_FULL_60_43|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVKVPTAPHLSCVGDSKAELRELLNLYKSSGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADCYFY
FVDRVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTDSIQAYG
EQVITEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>S0GV17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides goldsteinii dnLKV18|TrEMBL
MKVIDLINGSKTTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQNTDLYHEHATDLQEQVNNFNKGIAVDGSTFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVERCRAEGIDVPIIPGIKPV
VFKNQLTVLPKIFRSDIPEPFAAELRKCKNDDEVKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMATDSVYKVAKEVY
>A0A3A8W3I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium D16-59|TrEMBL
MINDLLNKTKTTLSFEVFPPKTEDEFQDIFSRLDALAALQPDFISCTYGAGGSKSGKTVE
IASYIQHTLHIDAIAHITCVGFRKSDLEENCKMLEKEGLNHVLALRGDRPKLMTDEQFQN
REFFYATDMIRYLKEHTSLKIAGACYPEKHFEAETFETDLMHLKEKVEAGASFLISQLFF
NNDVFYQFQERTAALGINVPICAGIMPITSAKQIGTSVSLSGSSVPKELSDMIANYGEKP
EEMRKAGIDYAMRQIQGLQEHGVDGIHIYTMNRSKMMEEIITQINSPTAKQQSN
>A0A3M3R6T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cannabina|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRSLLAQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VNFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLQLPR
>A0A1Y2ETG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neocallimastix californiae|TrEMBL
MKIIKKIEKAIQQKRTFCSFEYFPPKTPQGVNNLYDRFERMALLGPEFIDVTWNAGGVTS
DLTIEICSNAQTVYGLETNMHLTCTNMPVEKIDHALSEAKKAGVQNIFALRGDPPRGVKD
WTKCENGFSYAIDLIRYIKKNYGDFFGIGVAGYPEVHPDSPSKEDDLKFLKQKIDAGGEY
IISQYFYDVDLFLQWVKDCRAVGINCPILPGLLPIQTYDKFINMIRMNGTSVPENILNDL
EPIKDDDQAVKEYGIKLLTEMAKKLIENGIPGIHIYTMNLERSARVILENLGLAQSQEIV
KPLPWNRSLKNNRLKENVRPIFWRNRIKSYIQRTDSWDEFPNGRWGDSRSPAYGEVNLHS
SSSFKYPSEVCLKMWGNPEKPEDVFEVFSKYLKGEIKALPWCETALHAESSIIRERLINI
NKQGFLSINSQPAVNSVPSSDKVHGWGPKNGFVFQKAYLELFISTEKLTKLEQAIQSDEY
LSYYAINKKGDLKTNQKDESANAVTWGVFPGREIIQPTIVELASFLAWKDEAFSLWNVWK
DLYEDNSKAYNIIDKVSNEYYLINIVDNNFQRDNKIYEILEQL
>L1NKD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 380 str. F0488|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIAPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVEACKNNNEVKQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A1W9F304|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia nematodiphila DZ0503SBS1|TrEMBL
CVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFEGLDDDAETRKMVGANIA
MDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A519MC80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp|TrEMBL
CIGATRQSVREELAQLKAMGVKRLVALRGDLPSGYGAGGEFQYASDLVAFIRAETGRDFH
IEVAAYPEVHPQARSPEADLKAYVAKVQSGADSAITQYFYNSDAYFRFVEEAKRLGAEVP
VVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASIKAFGLDVVTDLCDRLRS
AGVPALHFYTMNQSAATLEICRRLGI
>A0A377ST26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Iodobacter fluviatilis|TrEMBL
MTPSPISFEFFPPRTPEGAEKLRTTRRQLAQFKPEFFSVTFGAGGTTQEGTLNAVLDIQS
EGHAAAPHLSCVGSSKESIRSIVQNYKDHGIRHIVALRGDIPSGMGDFGEFRYANELVSF
LRDEFGDWFHIEVAAYPEFHPQAQSAEADIRNFVNKVRAGADSAITQYFFNADAYFRFVD
EVNARGVTIPIVPGIMPIQNFSQLARFSDMCGAEIPRWLRLRLQAFGDDTASIRAFGLDF
VTELSDRVLAGGAPGLHFYTLNAAGAVSTVCQRLGR
>A0A4V0IFX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus porcinus|TrEMBL
MSYAKEINILNQTVADLDGKINVSFEFFPPKNEKMENMLWESIHRLKGLQPKFVSVTYGA
NSGERERTHSIVKNIQNETGLVAVPHLTGIDATPDELRVIAKDYWDNGIRGIVALRGDEP
PGYAKQPFYASDLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRAIT
QFFFDVDSYLRFRDRCVTVGIDAEIIPGILPVSNFKQLQKMAAITNVKVPSWMGKMYEGL
DDDQTTRNLVAASIAMDMVKVLSKEGVKDFHFYTLNRAELTYAICHVLGVRPR
>A0A251X818|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioflexithrix psekupsensis|TrEMBL
MMNMKTSALSCEFFPPRTAEGDSQLKQVQEQLKVLNPSYYSVTFGAGGSTQEKTYETVVD
IQNRCGVHAAPHLSCIGSSKTAISALLKAYQTQNISRIVALRGDRPSGMMGRIGDFNYAN
ELVQFIRECTGDYFHIEVAAYPECHPESRTASADLDAFVDKVAAGANAAITQYFYNDEAY
YRFIEACQQRGVTIPIVPGIMPINNFTQLVRFSDMCGAEIPRWLRWRLGELEHDRASLRA
YGLDVVTDLCRRLLQNGAPGLHFYTLNQAELTLEIARRLGMVTE
>A0A839XZQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter versicolor|TrEMBL
MTAPSCPKTMTHGPCGGVAADGGCEVAPGPCVFLDRPTVRWAGGDEPRPLAPEPPLLALM
RQRPVVVADLPAAPLSRESLERSVDALAGTVDAVLLGDSGGARVQFPPSHRAALVQARGV
PAWAGLNCRDRNRVALEGELAALADVGAAAVHCVTGDHTALGDRPDAQPVFDLDSTELAA
RAATAGLLVSVAEAPAGPPVRRRPLRLAEKVRAGARVCVVNHCGGPEAVAEFVAAALDAG
ADVPFVACVAVALDAASAAELRRFPGLVLPAGYLDAVEQARDPARAGVAAAVSLAEALLS
IPGVRGVDLSAVSPPGREPTTAGALATIGRALS
>A0A182LXW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles culicifacies|TrEMBL
MDVPITETIRDNNGALYTKLDRIFRSPTETSVPVSYSIEIAAKDDFKVGELERLTPQPIF
CALPWISDDNLRYADDFRRAPTLELSDQLSTAQYTVVNHVSCYNITEQQVDGLLSSGIRN
LFVIRGDTVQEEQTFQHSAALVRYLRKQQEERVLPKLTIGVGGYPYGHHQSPSKLEELRY
LKEKIDQGVDFLLTQTLYDAESFFRYREQCRTAGISIPIIPGIYVPYSYRHLRAMLNLTR
ITLLPAMDAAFAAHANDDPAQFEAFVVEHFVGVLRELLEPNVTSSDPIHSTSNASAAFHL
AAFFVTPTPVAWRPLALTSMVN
>A0A7Y9UVB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides perillae|TrEMBL
MPAEPLRPVPDEATGPDSHRIGDVVRTGERVISFEFMPPRDEAGAAQLWSAIRDLEPYEP
TFVSVTYGAGGTTRDTTVEITGRIARETALRAMGHLTCVGHTRQELVDVITAYRDAGVHN
ILALRGDPQDGPSAPWTPTEGGLSHAVELVELCHEVGDFSVGVAAFPEKHPGSESLEHDA
QVLAAKARAGADFAVTQLFFRASDYAELVDRAAAAGCDIPVLPGIMPITNLRQVTRMAEL
SGAEVPASLLARFEGLTDPADVRREGVRIATELCEELLAAGAPGLHFFTLNRSRATLEIF
EALRITV
>F2J1F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polymorphum gilvum (strain LMG 25793 / CGMCC 1.9160 / SL003B-26A1)|TrEMBL
MTEFQDGRRSRQTQTPPISASFEFFPPKSEKMEATLWSTIERLAPLAPSFVSVTYGAGGS
TRERTHRTVQRILTETCLRPAAHLTCVGASRAEVDAVVRDYWDSGVRHIVALRGDPLEGL
GARYRPRPDGYAYASDLVAGIRNVGGFEISVSGYPERHPESVDWQVEIDNLKRKIDAGAS
RVITQYFFDNDLFEAYLERIAAAGLSVPVVPGILPIQNFEQTIVFSAKCGTSIPQWLARR
FAGLDGDAETRKLVGAAIACEQVMDLVDRGLSDFHFYTMNRADLTYAICHMLGLRPAHPE
QQAA
>A0A316JWN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altererythrobacter sp. XM-24bin4|TrEMBL
MSPTLDQMHEARTALDSPLFKGLPGDIEVSFEFFPPKTEKMGETLWQSVETLKPLGPRFA
SVTYGAGGSTRTRTHEQVVRIQNEAGIPAAAHLTCVAATKEEVNEVARHYWESGIRHIVA
LRGDSPEGGGHYTPHPGGYANAVELIAGLKEVADFEISVAAYPEVHPDSPDAQSDLDNLK
AKFDAGATRAITQFFFNTRCFFEFRDKAAAAGINGEIVPGIMPVISFAAVQRMSGLCGTE
IPHWMEGLFEGLDDRPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GMRPKGGS
>V6KQV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomycetaceae bacterium MP113-05|TrEMBL
MALGTASVRTDSAPTIRDLLASGRRSYSFEFFAPKTEKGERTLWNALRRIEAVSPTFVSV
TYGAGGTSREGTVRSTERIANETTLTPVAHLTAVNHSRAELRHVMGCYADAGIRNVLALR
GDPPGDPMGEWIRHPEGVMYAADLVELIKEAGNFCVGVAAFPEMHPRSTDWDTDVRHFVN
KCRAGADYAITQMFFRADDYLRLRDSVNAAGCETPIIPEIMPVTNVRQIERFAQLSNASF
PPELAERILAVQDDPAAVRSVGIEYATELCARLQSEGVPGLHFITLNHSTATLEIHQNLG
LH
>A0A1V6D1R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium ADurb.Bin126|TrEMBL
MALTAECLVPLARGAGAIEALAAQFPSSLDAVVVGDNPQGAGGSPLACASILAGRKLEPV
LSMVTRDRNRIALNADVFGASALGVSGLLCLSGEHQALGACPQAGGAYDMDSVQFTAALQ
TLAEKGVDLTGQSVQDPPTFFVGAAAHPYLRPIELNLIRLKKKIRAGARFLITQAIFDLA
GFEEWMGAVRQAGLDKQAPIIASVLPLRSVEEALRMQAKPTYGPVGQDVIDRLKSASDVA
AEGIAIAVEVARKLKAIAGVRGIHILCGGCEEAAAVIVREAGLASA
>A0A2P5LE75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp|TrEMBL
MKPIAKKFDLSFEFFPPKTTEGMDKLREARAKLAKFNPEFFSVTFGAGGSTRDRTMDTVL
EIQREGYQAAPHISCISSSKSEIRELLQAYQAQGIKRLVTLRGDIPSGEVSAGDFKYASE
LVAFIREETGNHFSIEVAAYPEFHPEARTPAADLLNLKRKVDAGANSAITQYFYNADAYF
RFVDQCDALGINVPIVPGIMPIYNITQLARFSSVCGAEIPRWLKMRLEEYGDDMVSLRAF
GIDVVSELCETLLAWGVPSLHFYTLNQSNIISNIIENVQD
>A0A7U8JY84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella ceti B1/94|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNHFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A4S4BV91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metabacillus sediminilitoris|TrEMBL
MSFLEDLKSKILIGDGAMGTMLYSHGVDRCFEELNLSKPDDVIHVHEAYIQAGANLIQTN
TYGANDIKLSRYGLEDEIRQINKQAVEIAKRAAAGSTYVFGTIGGVRAFKKSAHTLEEIK
RNFREQLFVLLNEDVDGLLLETYYDFDELKTVLQIARKETNKPIITNVSLHEPGVLQDGT
TVKQAFLTLEELGANVIGLNCRLGPYHMLQALEEVPLLEHAYLSVFPNSSLPALNEGRLE
YESDEGYFKESALKFREQGARLIGGCCGTTPKHIKAMAEAVSHLAPITDKKVKIPKEIHI
QSTSADKDTLAPLQEIVKEKRSVIVELDPPKKLGMSIFLEGAQALHDAGIDALTLADNSL
ASPRISNLAAGLLAREKTNARTLIHITCRDRNLIGLQSHLMGLHTLGLSDVLAITGDPSK
IGDFPGATSVYDVSSFDLISLIKQFNEGVSYSGKPLGAKTNFSVAAAFNPNVRHLDKAVV
RLEKKIACGADYFISQPLYSNEQIVHVYEATRNLKAPIYIGIMPLTSSRNAEFIHNEIPG
IKLSDSIREKMAEAGTDKEKARQEGLAIAKDLIDTAFDLFNGIYLITPFLQYDLTVELTN
YIHEKEKQLAERKITHV
>A0A7W3E2Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. RHBSTW-00013|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIAQDYWHNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A6G7KAT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jeotgalibaca arthritidis|TrEMBL
MSTSQSNVSLSFEVFPPNSHVATKKLFGTLQELQDLQPHFISVTCSNRESRIEETTVRIA
DYLQNDLRIPSIAHLPASYLSKEQVTAIISKIEKAGIKRVLALRGDYLDGVEAKTDFVYA
NDLVHYIKTLAPNLEIFGACYPEVHPDSENRVTDIKHLKKKVDAGCNQLISQLFFDNNMF
YQFKEGCELAEINVPILAGIMPIVNRQQALRLIKVSDSHLPKKFLAILEKYEHNPIALRD
AGLAYAIDQIVDLVTQGVAGIHLYTMNQAETARHIHGATESLFLNN
>A0A7Y3R4W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 12-2(3-a)|TrEMBL
MGYTHASHIDALNQSISEVSDINVSFEFFPPSTPKMEETLWNSVHRLKNLNPKFVSVTYG
ANSGERDRTHSIIKAIKEQTGLIAAPHLTCIDASRDELITIADDYWHNGIQSIVALRGDI
PLGGGKPEMYAADLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPQWMAKQFDG
LDDDPVTRQLVGASQAIDMIRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPR
>A0A7Z0EBJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia psychrotolerans|TrEMBL
MTAASVPDLPRSGLPFSFELYPPRGAAAAAALTHTIDTLAAAGPEFISVTYGANGSSRTS
SLDVLRYILTETTVDPMAHLTCVGSSHAEASRLIREFLDAGVNSFLALRGDAPAGLAEGE
GYLGDLRSAGELVQLIHRVQAERVPYRESPVPGQPGARTLHTERAKVRIAVAAFPNGHPR
SRSTTQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRARHAGVEFPILPGIMPATSPA
RLRRILQLSGEELPSELAIELDVEPTVEGQRDIGIRHAARLATQLIDGGAPGLHLYAFNE
HDTVLHVLRRSGALPADSPIVQQVKESA
>X8GU29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shuttleworthia sp. MSX8B|TrEMBL
MQIREYLKEHTLLFDGAFGTYYTKQFRPEKEESFFPEYVNVSRPDRVKAIHRKYLSAGAH
AIKTNTFGAYPGILMKDAGETKKLITAGFSLAEEALLNHLSKDVKNRPETTGEFAKRAGQ
ERSAEASGEEDYFIFADLGPAPGEEEKERILAYQMAIDSFLETGARYFLFETLPEEKTVL
EAIRYLKDQCPGAYAISSFAVMPDGFSSEGCNYRDMLAAAAGESAVDAVGLNCMSSVWHM
DHLIRQIPDPGKPLLLMPNAGYPVVRGYRTVFEGNADYFARILARDAGQGVAMVGGCCGT
TPDHIRLLADRLRENPVRRQGGQGPVFKGPDPALGQDHGKRRDQHLYAVTGGDGNSSDKD
SSDKGSSDSGLSDRDLSVSKDQDAFYQKLMSGRKVVAVELDSPRGCDITRFMEAAENLKE
AGADIITIADNPIAKARMDSSIVAGIIRRQVGLDALPHMTCRDRNLNATKSLLLGNYAQG
IRNVLVITGDPIPSARRDEVKVVYQFNSRKLMAYMKALGQEEGTFPSPMHIFGALNVNAK
NFEIELDRAREKVQAGAVGFLTQPALTTEAIANICRASETLRAENSRIRLLGGIIPVISE
RNGRFMQSEISGIDVPDALIERYVGKDRADCEEIAVDSSLELAKTMEDAVDGYYLVTPFM
RDYLIRRIMERLPGR
>A0A0P0Z9P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fulvimarina pelagi|TrEMBL
MLKPRPTSQPIRVSFEFFPPKTEKMEQTLWQSIERLAPLQPDFVSVTYGAGGSTRERTHQ
TIERILKETNLTPAAHLTCVDASKEEVNEVVRQYRQTGVKHFVALRGDSQLGVGEEWHGH
EDGYRNGAELTEGIKEIDEDIEVSVSAYPEKHPESADLMTDIDLLKRKMDAGATRAITQF
FFDNDTFERYVERVRKAGIYIPIVPGIAPVHNFTKIASFAGKAGASIPDWVQARFEGLED
DPLTHSHVAAACCAEQVLDLSHRGFSDFHFYTMNKADLVYSICHILGLRGRQAETPVALQ
DAAE
>A0A2E2J9C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polycyclovorans sp|TrEMBL
MTASRDPHFSFELFPPRTPPGWAKLPALINELARVKPSFFSVTYGAGGSDQNGTYDTLIK
VVEQTGIEAAPHLTCVGSTRANIAALLQQYRDAGVKRIVALRGDLPATAMSSAARGEFRF
ANELIEFIRDAHGDAFALEVAAYPEIHPQATSPEADFDAFVRKVQAGADGAVTQYFYNAD
AYFDFAERCDRAGLKVPIVPGIMPIVNTQQLLRFSAACGAEVPRWVRLRLEAFGDDKRAV
QDFGLEVVTRLCDTLLKNGAPGVHFYTLNQAEPTLKLWRNLGLPG
>I4LY66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis 1400E|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIHSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKSGINVPIEAGVMPVVNANQVKRMTKMCPSKISEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A380W5W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afipia felis|TrEMBL
MSDTNPSAHTQAKRPAISFEFFPPKTEEMEQNLWGVINRLAPLTPNFVSVTYGAGGSTRE
RTHSTIKRILDETSLTPAAHLTCVDATCADIDDVVDRYHEIGVRHIVALRGDPSGGIGTA
YRAHPEGYQTSADLVASIRRRHPDMEVTVSAYPEKHPESATIDADIDVLKAKVDAGAARA
ITQFFFDNDLYFRYLDRVRKAGIEIPIVPGILPVQNFKLAKNFAERAGATVPDWLAAKFE
GLDDDAETRKLVAATVAAGQVQKLAKQGVENFHFYTMNRADLVFAISHLLGIRPNGSQQA
A
>A0A5C8WMM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. WL6|TrEMBL
MPNANRHRASRDGYHPIRVSIEFFPPKTEEMEKILWSSIERLAPLGPKFVSVTYGAGGST
RERTHNTVARMVTETGLKPAAHLTCVDATRDEIDAVVQSYWDAGVRHIVALRGDPAEGVG
HAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFENDVYLRYVDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
DGLEGDVETRRLVAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKV
ATAKAA
>A0A374SXS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. TM04-29|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFNTPSVAHLTCVGRSHADIAAKIDEYRSAGVENILALRGDLPTGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A5Q0LIX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces fagopyri|TrEMBL
MALGSASTRTDRARVVSDMLASGKKTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCGTPVIPEVMPVTSVKMLERLPQLSNASF
PDVLKERILTSKDDPAAVRSIGIEFATEFCAKLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A2N2EIU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-1|TrEMBL
MVISLELVPNNEELLSQQLSYVKSNFPNIEGINIPDLLKFEMRSWEGCRIAKGYYQRTIP
HIRAMDIDLEEPLPMAKSLIENNICEVLILTGDLPQDMNRKIYHSSTIDVIRKFKTELPH
IKVYGAIDQYRDSFKTEMLYVKRKIYAGVDGFFTQPFFDMRLLSIYEEMLSGTNVFFGIS
PVLSEHSQNYWHAKNNVIFPEGFSPNYDWNIDFAKKATEFADSKNRNLYFMPIKTSLEQY
LHSVFR
>A0A2K2FZ40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium guangzhouense|TrEMBL
MTASHRAAESPLFAGLPGDISVSFEFFPPKSEKMEEQLWDAITQLAPLDPAFVSVTYGAG
GSTRERTHATVSRIVKETSLVPAAHLTCVAASKAEIDEVVDQYWEAGVRHIVALRGDPPP
SDGGRFVPHPEGYASAAELVVGLKKRHDFEISVAAYPEVHPEAVSAQVDLDNLKRKIDAG
ATRAITQFFFSTDAYFRFMDKVLAAGITAPILPGIMPVTSFTAIRRMSGNTEIPGWLETM
FDGLDDRPGPRALVAAVAAADLCKRLYEGGVRDFHFYTLNRAEQAYAICQLLGLRPAKEL
VA
>A0A4R6WWK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dongia mobilis|TrEMBL
MLLSPTPEPTPDPAVARSAPADFRRRPDRPAAPRLSFEFFPPKPDQPVAAFWRTVADLAA
LDPQFCSVTFGAGGSTRRATGTIAAEIQDRHGLPAAAHLTCVDATRAEIDAIASGYWQTG
IRHIVALRGDPRGGAGGAYSPARDGYAYADALVAGLARRHAFEISVAAYPETHPQAASAA
ADTDNLKRKIDNGASRAITQFCFDMAAFERFLDRAARAGVAVPIAAGILPIVNFARLESF
AAACGAHLPADLRRAAAGIDDEPLRRHRFAVDLAIAQCDALYRLGIRDFHFYTLNRAELV
KEICDGMGWSPLVQRAAN
>A0A0G2ERS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diplodia seriata|TrEMBL
MEKITDKLAALPPDGRYFSLEFFPPKTQMGFANLQNRLERMANALRPLFVTVTWGAGGST
ASKSLELAELTQRQLGLTTCLHLTCTNMSRSLVDDALEQAKALGVRNILALRGDPPRSEE
YREGQAGTDNDSNKDFTWAVDLVRYIRDKYSDYFCIGVAAYPEGHSDQSHPDKQDPKFDL
PYLIEKTKAGADFIMTQLFFDIKAYEEFEAMLRNDPSGVFKTIPIIPGLMPIQSYQILRR
TTKLSHAKLPPAILERLDAVKGDDEAVKSVGVDILSEVVEELKARPNPGPRGFHFYTLNL
EKAVAHIVERCHLITATSPDNDDEEAVTIDDIPVNGETPSDSLKVKNRRRLSSANSTPHN
RVVVDRPSTSSNKSYEALADEAGVPKDKIMTRANTLAISEGEGTLGREATWDDFPNGRWG
DARSPAFGEIDGYGVSLHVSIPQAIKLWKYPTTVEDISDIFRRHIIGELEAIPWSEEGLN
AETETIRDQLLKLIAKGWWSVASQPAVNGIKSTDEVFGWGPKNGYVFQKPFVEFFLSSAD
WKKLQAKLDELSDVTYFAGNHAGDYSSNDEDSVNPVTWGSFAGKEIVTPTIIESVSFRAW
LEEAFSIWSEWRHIYPPRSATANLLGHIRDDYWLVNIIHHDFVEQDALWRLLFEE
>A0A838TBF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagales bacterium|TrEMBL
MKVIEYIQRSNATMVSFEILPPMKGRSIQSIYDTLDPLMEFKPPFINVTYHRAEYIYKRN
REGLFEKTIIRKRPGTVGICAAIVNKYHVDAVPHMVCGGFTKGETEDALIDLAFLGIDNI
LIIRGDPNRNENSFDPEPGGHAHAIDLMKQAVNMNRGIFLEEDLSDVSPTNFCIGVAGYP
EKHYEAPNMKMDLKYLKEKVDAGAQYVITQMFFDNNKFFEFVNRCREIGIEVPIIPGIKP
ITSKKQVNTLPRLFHVEVPEELATELETTITDEAARKVGIEWCIQQCRELVKANVPLLHF
YTMSNPAPVKAVVSNVF
>A0A6B0WK38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MLSKLRRAPLSGETLGARHYRLHLVRDLTFEVIPLKSLDAAIEALPAGSRVSVTASPVKG
QDATCEITERLMELGHEAIPHVSARLVDDRARVSELAGWFRSAGVSTMFLVGGDVESPGA
YSDAASFLRDLLECDHGLSTIGVTAYPHGHPLIAEEVLHEALHAKQALLAEAGVEGYCST
QMCFDPERIEGWLRGERAAGLTLPVHLGISGVVDRAKLLTMGARLGVGPSLRYLRKNRAA
IMKLMTSPNYDPDHILMALSPSLDDLGVTGLHVFTFNQVATTVTWQSSHHG
>A0A8A4TR91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfidibacter corallicola|TrEMBL
MNKSFRDLLGEEKPILLDGGIATELYDKGVFINQSFDYVNLSHPEWVKQVHEDYIAAGAD
VIETNTFGANRVRLKVFGVENELERINAAGVQIAREAAGSNKYVAGSIGPLGVKIEPYGP
TSFAETRRIYREQAEVLHREGVDLFLLETFSRMAELAEAVAGIREVSDKPIVGMLTVNDH
GQTLYGTEPVFLVPELEKMEVDAIGLNCSVGPRIIYDALEQMVKYSGKPICAMPNAGNPK
SVDGRNIYLCTPEYMATYAKRFMKIGIKIIGGCCGTTPEHIRAMAKAIGQSQSSNLKKKH
DQVPSVQVDDDPLPVLPLAERSQFGGKLARKEFVFSVEVVPPKGCDPTKTLKKIRLLKEH
DVDAVNIPDGPRASSRMSPQIMAILVEDRIGIETILHYCCRDRNILGIQSDLLGDFAAGL
KNILAVTGDPPKLGDYPDATAVFDVDSIGLTNIIHRLNQGLDIGNNQLSKPTAYAIGVAL
NPTALNVEEEISRFRWKVEAGADFAITQPVFDVDQFMRFYERVADFDIPIVAGVWPLVSF
KNAEFMNNEVPGISIPPAILERMSRAESSEQAKEFGLDIAIENVRQMLPYIAGAQISAPL
GNVRFALRVVDRIRDLLKVEGRA
>A0A7M2Z217|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gaiella occulta|TrEMBL
MAGLASPETSSAARLAELLRASRYEVIPLAGVEEQVLEHVPRDVTLTVTASPTKGLDVTL
DHAERFAAQGYAVVPHLSARLVRDRSHLAEVVQRMDAMGVRDVFVVAGDAERPAGEFAGA
AALLAALDELGHPFADIGITGYPESHPTIDDETTIAAMFEKSRFATYIASQICFDPSLTV
RWVDAVWARGTRLPILVGLPGVVPRAKLVRVSARIGIGESARFLRKNAGFVGRFLKPGGF
SPDPLIRGLEPALRDPERKIAGFHIFTFNDVADTERWRRRRLARA
>A0A7M2YWZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gaiella occulta|TrEMBL
MDLVERLRSGPPIVADGGMGALIGGAVQRLRCPEEANLRAPESVVAVHASYIRAGAELIE
TNTFGANRRKLASHFLEGDFEAINSAGVRLAREARDVSGREVLVAGAIGPLGELELLDAS
EHGALYAEQARILEGRGVDLFMVETFFDLEDLVVAVQAVQSVSALPIVALLTFDEEAETS
GGVGAADAARRLAGLGVAAIGSNHGAGPQATLAAIDAMRGAQVPVAALPNIGLASLSGGR
VVYPHSSPDYFAEFAAQAAALGARIIGGCCGTTPAQIEAIRGALDEGRAPRVVFEAGEPA
LAAPPAADAVETGLARALRLGEWVVSVELDPPKGGTNDAMIDVARALRASGHVGFVDVND
NPMARARMNALMASIAIQREAGMETIPHVTPRDTTVMGLEGILLGAHAEGVRNILAVTGD
PPQVGDYPGSRGVYEVDSIGLVQLLARLNQGEDYVGKTIDQPTSFFVGVAVNPSAHDLPL
EVDRFERKVAAGARFAMTQALFDVAHLDALLDRYGGQPPVPLLVGVWPLRSHTMALRLHN
EVPGISVPERVLDALRDAGAGAPAVGLALARELVEQVRERAAGIYVIPPFKRPEAALELF
SG
>A0A5M4DBJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MNPQVKLSDALAQPVVCGDGAYGTLLAARGFPKQPYDLANLEAPELVADLHRLYFEAGAV
LIETNTFTANRFRFVDLRDDLYEINRAGARIAKAACGDGAVILGAIGPAGKPMYPLGSIS
SSEVIESAREQARALDEGGVDAFLLESFLDLDELERVVEGVRQASNLPIIASKAFIEDGE
AISGGLPYQCAKRMAAMDVAAVGANCVVGPQRMLDLVRMMTEATSKPVLAYPTPGMPTLI
KGRVAYDTDPTYFAKACRRLAEEGAALIGGCCGTTPDHIRALSQELGRSPVQRAKRASVA
ARDYETKPLESTPRTEFGERIARGESTYSVELDVPRGLKLDRLMADVEAVRAAGAHTINI
SDGARARLRMNPTAVCHLIQSTTGAETTMHFSCRDRNLLAIQADLLGCHALGVRNVLAIT
GDPANIGDYPSATSVFDVDAVGLVRILGRLNEGIDLAGYGIGRKCGFTICVAFNPGSPRP
EVELVRLQQKADVGAHAVYTQPVFDESLVEIALESCKKVGLPCLIGVMPLRNARHAEFMH
NEVPGILVPERLRAALADAPDDEAALDLGIGQALRLARLAKSGGAGVYLMPPANRITAAV
KVLEGIR
>A0A353Y7N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Curvibacter sp|TrEMBL
MSEQQLPISIEFFPPKTPEGVEKLRAVRQQLYALQPEFCSVTYGAGGSTQEGTFAAVREI
LAEGRDAASHISCIGATQATMRENLAALQAMGVRRLVTLRGDLPSGYGAGGEFQYASDLV
AFIRAETGDHFHIEVAAYPEVHPQARSPESDLKAYAAKVRAGADSAITQYFYNADAYFRF
VEESDALGLSVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIKAFGL
DVVTALCEQLRAGGAPALHFYSMNQSAATLEICKRLGLPG
>R4XG29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Taphrina deformans (strain PYCC 5710 / ATCC 11124 / CBS 356.35 / IMI 108563 / JCM 9778 / NBRC 8474)|TrEMBL
MQNLYDRMERMASWGPPLFVDVTWGAGGRLAELTTDMVQTAQEMFGLDTCMHLICTGMPS
EKVKEALKDAYDSGCQNILALRGDPPREQEKWEATEGGFRYATDLVKYIRAEYGDYFDIG
VAGYSEGHPECLDKSQNINHLKEKIDAGANFVVTQMFYDVDIFLSWVQDCRKAGVLVPII
PGIMPITGWDSFLRRAKWSEAHIPQHFLDALEPVKNDDAAVRERGTELLTEMCQTILDSG
LHHLHFYTMNLEKATNMIIEALGLLKDVQKREMPWQRSLGLNRKDESVRPIFWANRHKSY
IARTKEWDEFPNGRWGDSRSPAFGELENYNIGLRVPPEEVPKLWGSPETLQDVADLFSNY
CLGNVTCLPWSDSALAPEATVIQKKLAAINNKGYLTINSQPAVNGAKSTDPLYGWGPKNG
YVYQKAYLEIFVHPGLLQAFIQRVEADPSNTYYAVNTLGDLKTNTKSDGPNAVTWGVFPG
KEIIQPTIVEAISFLAWKDEAYRLGTDWANSYPKDSVSRNLLSAVMSDWYLCVLVSNDFM
SENALFTLFDDLAPVTSLTEPKTSNGAVDGDMEVHR
>A0A2E8DCN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTFELIPLGNLEDQIRFIPTGSTVSMTCSPXRTVEDTLDLCEXLGXYGFATIPHIAARMV
EGEAHVDQLVARITGLGIRKVFVIGGDXEPHGPFTDAAGFLRSFLGRKPDXDVVGIGSYP
DGHXTIPDDALVDALLEKQELIAEAGLEGYMSTQMCFDHQKIGNWLVERRAAGVTLPCYL
GVPGAVDRTRLLTISIRLGIGHSARYLKKNRSSVIRLLSPGXYNPNKLIGPLSKRAXDLD
ITGIHCFTFNAVDTTEDWRQKALAGLKH
>A0A2G1Y8C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robiginitomaculum sp|TrEMBL
MIIEETRNNRDFHRNGHRPVPGTLARASSSGGEHINISFEFFPPKTEKMGETLWQSIQKL
ESLNPDFVSVTYGAGGSTRERTHQTVARIVKESSLKAAAHLTCVGSDKAEIDEIAREYWQ
AGVRHIVALRGDPVGGLGAPYVPVDNGYAYASDLVTGLKNVADFEISVSAYPELHPESLN
WDDELDNLKRKIDAGATRAITQFFFSADTFXRYLDKALDAGIXIPIIPGLMLQPNYRGLT
RIAKLCYISIPDWYHNLFEPLDDDPQTRLLLTASTAADLAAQLRAXGVDHFHFYTLNKAD
LAFTTCQILGVKAQNTXAQKVVT
>W0HYJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sodalis praecaptivus|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEQTLWQSIDRLSELKPTFVSVTY
GANSGERERTHSIIKDIKERTGLDAAPHLTCIDATPHELQAIAQDYWRSGIRHIVALRGD
LPPGSGRPAMYGADLVALLKKVGDFDISVAAYPEVHPEAKSAQSDLINLKKKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDTEIVPGILPVSNFRQLQRFASLTNVKVPNWMTAMFD
GLDHDLETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELTYAICHTLGVRPEIKAAP
AANRAAG
>A0A2E0II74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ahrensia sp|TrEMBL
MNTIGMDTADSRPKHIPASIEISPKQAVESPDLPGLFPAGVRVYITDIGTDPTETLVAAA
KRVTDLGYTAVPHFASRRLSTKAALEDRIKATTQEAGVHDILVIGGGLEKHAGDFSSSME
VLETGFLDKYGITHVGVAGHPESSPDFSEEVAVEALRLKKGFGERTGAKVRIVTQFGFDG
EKFIKWAEGLRAHGIDMPVHLGVAGPAKITTLVKYAAMCGVGNSLDFFKKRTRSLATLAT
SHSPEGVVGPIEKHWQDNPQTAIRQVHVFPFGGIKKAAGWLEERGTWDIKTSLYPSMNSK
S
>A0A3L8BFC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ketobacter sp|TrEMBL
MNSQQQHEKRFSFEFFPPKTDVGVEKLNLVQQTLAEKKPRFFSVTYGAGGSTRDRTFETV
NNVKNRTGIDAAPHLSCVGDTKAQLAQLLNQYQDAGINRIVTLRGDLPSGMGASLGELKY
ASDLVAFIREQSGDHFHLEVAAYPEMHPQAKSMDADLQAFKTKVRAGANSAITQYFFNVD
AYKFFVDSCEKMGLDLPIYPGIMPIINFDNLIRFSSMCGAEIPRWIRMRMECFRGDEQSI
KQLGEEIVTSLCEELLAMGAPGLHFYTMNQAEPTIAIWDNLNL
>A0A3C2DCD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTYELIPLKNLTDQSEHLPSGATVSVTCSPAKTIDDTLDLCAEYADKGFAVIPHIAARMV
EGEDHVDRIARRVRDAGIRKVFCIGGDADPRGPFADSAAFLRSFLDRRPEIDAVGIGSYP
DGHAAITEQVLDDAQVEKQEIIRQAGLQGYMATQMCFDAQTIVAWLERRRAAGVSLPCHL
GVPGAVDRTRLLAISIRLGIGHSARYLKKNKASVIRLMSPGGYNPNKIVAPLSSRANELG
IEGIHCFTFNAVDTTEVWRRKSLKKLGA
>A0A2E7SNS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MGSNQKSNNGHERKSIQLRLIDEMTYELIPLKNVHEQAEFLPQASTISITCSPAKDIEAT
LELCEKFLSKGHNTIPHFAARMVESEEHVTRIVKRIETLGIETVFIIGGDADQRGPFNDA
PGLLKSFLDKNPTIKTVGIGSYPDGHPSIPPEALSEALIKKQEMIYESNLNGYMATQMCF
ETETISDWLENCRKSGVTLPCHLGVPGVVDMKKLINISLRLGVGISTRYLKKNRKSVFKL
LSPRGYNPNKLIAPISSRADELNISGVHCFTFNAVDSTVDWRTKTISRLI
>A0A351EUV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSSGRLSRCSRPFAGIRRFSERCGTTIPHWIHELFAVLEDAPEVHQMIAATTAAEPCRQL
AEHGVNQFHFSTMNKPEITAAICRLLGVTPASGRSRQAQVS
>A0A378NBM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mannheimia haemolytica|TrEMBL
MQKLYLLVQQKWRMLWDSIDRLSPLKPKFVSVTYGANSGERDRTHSIVKSIQEKTGIISA
PHLTGIDATPEELKVIAKDYWDSGIRRIVALRGDIPKGYDKALFYASDLVALLKSVADFD
ISVAAYPEVHPEAKSAQADLLNLKRKIDAGANHVITQFFFDVESYLRFRDRCVSIGIDCE
IVPGILPVTNFKQLQKMAAVTNVKIPTWMGKMYEGLDDDQTTRNLVAASIAMDMVKVLSR
EGVNDFHFYTLNRSELTYAMCHTLGVRPDLTTA
>A0A2E4SVR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTYELIPLKNLADQGIHLPTAATVSVTCSPAKTIDDTLDLCAGYADKGFTVIPHFAARMV
ESKSHIERIVERVHAIGIRKVFCIGGDADPRGPFTDAAGFLRSFLDCGPDIDVVGIGSYP
DGHATIPNQALDDSLIEKQEMIREAGLGSYMATQMCFDAQTIGDWLAGRRKAGVDLPCHL
GVPGAVDRTRLLTISIRLGIGHSXRYLKKNRTSVLRLLSPGGYNPNRLIAPLSSRADELG
IAGIHCFTFNAVDTTEAWRQKSLRKLAS
>A0A4Q9RP88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meridianimaribacter sp. CL38|TrEMBL
MKVTEHIKQAKGKTLFSFEIIPPQKGSNIKELYNNIDPLMEFKPPFIDVTTSREQHVYIE
KDGLLDRKITRMRPGTVGICASLKYKYNVDTVPHVLCGGFSREETEYLLVDCHYLGIDNV
MALRGDAMSHQKYFEPSKGGHQYASELVEQIQNLNKGKYLHDVIEASDKADFCIGVAGYP
EKHIEAPSLQSDLKRLKHKVDCGADYVVTQMFFDNKKYFEFVEAAKQAGITVPIIPGIKP
IATKKHLQLLPQVFKIDLPEDLIDAVEDCKDNKAVRQVGVEWAIKQSKELQNAGVPVLHY
YSMGKSDNIKAIAERLF
>A0A2N7ASY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus nuruki|TrEMBL
MTETNKTPTLSFEVFPPNSEVGVDKLTDTLDQLKELHPSFISVTASNHKLNYEKTTIDLA
KYVKDALGCNTMVHMPAAYVTKVEVDNVLNRLEKMHINQVLALRGDIVDGYVPETDFKYA
SDLTSYIKKQKPYFEVSGACYPEVHPDSKNRIDDIKHLKNKVDAGCDQLITQLFYDNDQF
YRFQEECAIANINVPILAGIMPIVNRKQALHVIDNCAARLPKKFINILDKYKDNPVSLKE
AGIAYAVDQIVDLVTNDVEGVHLYTMNKSDTAKHIFSNTASLFNLKNI
>A0A4Q7YEI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. BK022|TrEMBL
MVERVPGVSGGAGALLDGVSLEMTGKDVPRLEEARTSLDGGTRINVTYLAGEDAGMRLAA
ARAVREQGLVPVPHLSARRLPSSAELERFLAGLAEAGAVDNVFVVGGDPARPEGPYEDAL
SVISGGLLQRYGVRHVGICGYPEGHPAIGDDALWSALTGKAAAIAEAGLAGDVITQFGFD
AEAVLGWLEALRERGVHLPVRVGVPGPAGVRRLLGYATRFGVGTGASVARKYGLSLTNLM
GTAGPDRFLDDLAGGYDPSRHGAVKLHFYTFGGLRTTAEWITRYRGERG
>A0A1F4TQG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-1 bacterium RIFOXYC2_FULL_41_25|TrEMBL
MKVSEALQKGQPTLSFEFFPPKTAEQEARLFEVIAQLKDFNPDYVSVTYGALGTSAGQSF
RWVKDIKDKFGIAPVAHLTCVASSREDINTKVKELVNIGVENILALRGDIPEGLVEKASP
ADGCRHACELVAFIKELYPFICLGVAGYPEKHPEAPNLESDIKYLKRKVEAGADYIVTQL
FFDNGVYFDFVRKCRDAGICVPIIPGIMPITNYKLLRKMTSICGASIPKELLTQLEKNQD
DNEAIKKIGIEHAVRQCQELQDAKVPGLHFFVMNQAGPISEILKQLS
>A0A2D6U7Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MALFKKNEVPEIVESDEARAHREHLTRXFTIEVIPMKSLDNAREHLPAGAPLSVTASPVK
GLEETQRLTEEFQAAGFEPVPHISARMVRDRAHCAELAHWLRDNGLKKMFLVGGDQDPPG
EYFDAVLFLQDFLEQDHGLEGLGVTSYPDHHAFISDEKLHEALHAKQTLLAEAGLPGWCS
TQMCFDAEVIEAWLRKERAEGLTLPVHLGVSGVVDKAKLMTMGVRIGLGTSLGYLKKNRA
AITKMLTSTSYDPNDLMMPLSNAALELGIEGVHMYTFNQIEATEQWRAEALAELAG
>A0A0Q4KYK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf34|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGISFEFFPPKTEKMDTQLWEAIRTLEPLAPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGDPNADIDNL
KRKLDAGASRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKSDVTVAAA
>A0A1G6I038|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Succiniclasticum ruminis|TrEMBL
MKIINILKGSKPGVSCELFPPKQGSQLANALEIVDTIAEQKPSFISVTYGAGGSNAGEAV
AVAAEVHKCGIPSMAHFTCINADDQRIEAMLKQLQAKGIDNVLALRGDLPEGTSLEHAEY
QHASDLAKKIKSFGDFCVGGACYPEGHPESAGLNDDIEKLKIKVDSGVEFLVTQMFFDND
VMYNYMYRLLAHGITVPVVPGVMPVTNAKQIQHICKLSGTKLPLRFRAIVEKYGDDPEAM
KQAGINYATAQVLDLLANGFMDVHIYTMNRPEIIGGILQNLSCIVK
>A0A3B1DC76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MNISFEVVPRDVDSLKSQLHFVETHLPFVETINVPDLLRLPVRSWEAGKHIAREKYRFIP
HLRAIDFDLKEMRLERMIEECELDTVLLVSGDPPPNRLHPIYDTHVLEMIAKVRASFPAI
KIFAAVDPYRSSLKREKAYMLKKLDVGADYLMSQPFFDMRLLEIFSELIPSEKAYWGISP
IVKDQSRAYWEKMNQVVFPSDFKATYDWNIAFAEKVLNFCRLKGGNVYFMPISIDLEKYF
SPIADFLEKPLPSE
>A0A1W1BNS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MGFLDKIIAKNIQRDFYTLHLLLFWVFLDKILRYITIKSLFMFEQFCKTLCSNEPYITVE
VNPPHGSSINSVLKSIESVGLQDKITGFSVTDNPLAKLKMSGILSAIKLQQKFGKPVIAT
MSMRDKNKLSLQSSLLGANDFDLRCILALTGDPAKFSDQPEVKGVLERDSTLLLSIIYHL
NNGVDYSNKVLNPKPKPIYPFAVTNSYARNMKSLQKRVIKKLDYGARAIITQPVYDLENA
KELLEIFDEAKAMSIRDTAKDAQLILGQFPIVRSRTANFIDDRVPGISVPKNIIDEMNLA
AMDGEDKEQEVGFALSKRLFDEVMNLHPKVHLMTHNRFNLCSDLIGE
>A0A7V8FAP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter sp|TrEMBL
MIPFDKRRAALDLTQAYSLEVSAKAMPALTDAAPRIAPGSIVSVPYLPGEDDDARLAAAR
AIRALGFTPMPHLAARRIASHDELESFIQRAVVEVGVEHCFVIAGDPATPKGPFPDSASL
IDTGMFERAGIKTVGVGGHPDNHPVMSTDDRWDVLEHKCRSIAMRGMAPLIVTQFVFDAD
IALSWLETLRERGITYPVRIGVPGPAGIAVLIRYAALCGVGACASMLSKYGVSLGKLLGT
AGPDHFVDRLATGLTAAHGQVDLHFFPFGGVVQSVRWLEQYRERVELAR
>A0A7Z2Y3X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ADAK7|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1W1CD37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MFEKFCKTLHNDKPFITVEITPPHGASIQPIIQKIKELRLHEKVAGFSVTDNPLAKLKMC
GVLSAIQVQQAFKKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKYSDQPE
VKGVLERDSTLLLSIIYKLNNGFDYSNKELNPKPKPIYPFAVANSYAKDMRRIQKKMVKK
LDYGSRAIITQPVYDLENAKELIELFEEAKTLSVRETAKDAELILGQFPVVRAKTANFIS
DKVPGITVPKKIIDEMNLAAMDSTEKEQEVGFAISKSLFDDIIKLHPKIHLMTHNRFDLC
SALIDNN
>A0A352W116|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetia bacterium|TrEMBL
AADIIGFNCSPGPHLMLRALEKIKKFPVKPVVVKPNAGTPREHEGRNFYMTSPEYFAEFA
KRFIQNGVKVIGGCCGTNPEHIKAVRSAVKALFPAERTVVSFPEQNEKKPVGATPVPQPE
KSALAAKLAAGQFVTSIEITPPRGVDPSSVIEKAAQCREAGIDAINIPDGPRASARLSPM
ITALRIQEKSGIEAVLHYCCRDRNIIGMQSDLLGAAAAGINNILSVTGDPPKLGDYPDAT
AVFDIDSIGLCRIISRLNHALDIAGNPIGKPAKFLCGVGVNPGAIDLEKEMARLEQKISA
GAEFIITQPVFDLEVFFKFYRIYEKFTTRIPLLAGIWPLASLRNAEFMNNEVPGAQVPEK
IMERMRKKPSGEEAKNEGINIARESAREIKPLIQGLQVSAPFGNIRYALQVLDI
>A0A1W1EIP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MFDNFFQKLQSRDRFITVEITPTHGASIDSIIENISKIELDKKIDGFSVTDNPLAKLKMS
AILSAIKIQQQFNKPVITTMSMRDKNKLSLQSSLLGANDFDLRCILALTGDPAKFSDQPE
VKGVLERDSTLLLSIIHHLNRGVDYSNKILNPAPKPIYPFAVSNSYSKNMARLEKKILKK
LNYGAKAIITQPIYDIDNARELLEIFDSAKSQSIRESAKDAQLIIGQFPVVRARTTNFIS
DNVPGITVPKEIIEEMNLASMDSIEKEQEVGFAISKSIFDEVMKLHGKVHLMTHNRFDLC
NDLIS
>A0A3B1DC53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MSFREALESGKFVVTAEVGPPKGTDIAEMVHHIELLKGKVEAINFTDNQSAVMRMNSLAG
CAIAVEHGVEPIFQMTCRDRNRIGLQSDLLGAYALGVKTVLCMTGDHVSAGDHKGAKPVY
DVESVQLLRIVDSLNNGKDMAGNDLKGGSDFFQGGVVTPEANPLEPQLMKFEKKIQAGAR
FFQTQAVYDIEKFREFMKHARKFPVKILAGLVVLKSAGMANFLNNYVPGIKVPQELIDEL
KAAGKGKGLDKGIEICARHIKQLRDEGICDGVHIMAIGMEDKVPEIMERAGILD
>A0A838L7F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas chungangi|TrEMBL
MDWGNLSRDFSLEITRKDLGDLVDNATLLPAGSAISITYLPGDRIEDLAQVAASVRRLGL
EPVPHISARRIRSDEELARFLRTLSGEAGIRRAFLIAGDLAEPLGPYADALSLVESGLLE
AHGITRIGVAGYPEGHPAIPEDVLRAALADKIAAAASRGLDLEIVTQFLFDADRIADWVC
TLRAQGIRHRVRVGVAGPASVQALLRYAARCGVGASAKVMAKYGVSLTRLLAQATPDRLL
TRLGERLADAGEQNVKLHLYPFGGLSKTVRWMHAYAAAAPAIA
>E1TCG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. (strain CCGE1003)|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLAQLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHLSCIGSSKESLRAILNQYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCQRLIDAKAPGLHFYTLNGAAATKAICERLKG
>A0A496DCT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. AM44-16|TrEMBL
MKVIDLIRDSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIHYLKEKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A1G3Y5C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfovibrio sp. RBG_19FT_COMBO_42_12|TrEMBL
MDFKEALKSKNFVVTAEIGPMKGTDVQETLKDAELIKGKVDAINVTDLQSSVMRLGSMAV
CHLLKDHGIDPIFQMTCRDRNRLALQSDLLSAWVLGIRNVLALTGDHPTMGDHPQAMPVF
DLDSVSLLRVIGRLNEGFDMGGNQLKGAPDFFPGAVVNPGADTEAALEMQIIKMEKKIEA
GARFFQTQGIYDLKLFEKFMKRVESFKTPVLGGVILLKSAGMARFMNKNVAGVFVPAPLI
KEMEETKDKVKTSIEIAVRLIRGMKDICQGVHIMAIGWEKKIPMVLKEVGL
>A0A1H3J374|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas sp. OK242|TrEMBL
MAKKNFSIEFFPPKTPEGAEKLRVTRAKLAELHPKYFSVTFGAGGSTQKGTLDTVLEIRR
EGHEAAPHLSCLGSSRESLRSILTQYKDNGIKHLVALRGDLPSGYGAMDISSGEFRYANE
LVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDVQRYVSKVKAGANGAITQYFYNADAYF
RFVEEAQKLGATIPVIAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTDSIRAF
GLDVVTQLCERLLAGGAPGLHFYTLNQSAATIAIWQRLKL
>A0A2I1Z0K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQITDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQFLG
>A0A2A9EQW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Isoptericola jiangsuensis|TrEMBL
MVAEAQPHPHRPTVSFELMPPRRPDAAPRFWETARRLVDARPDFVSVTYGAGGGDRDTAR
EVVSTLLAGTSVLPVAHLTCVGASREDVSDVIDSFLEAGVRTVLALRGDPPKDQPDWRPP
ADGVHSSVELIALLREVEARRCASDPSTALRGAARPLTIAVATFVDGNVQAGTTRAQEVQ
RLLEKQQAGASFAITQLFYEAASYTDFVTEARAAGVTIPILAGLLPTTDPRRLRRVEELT
GVRAPQHLLDALDALPDPEAQHAYGTAYGSELAQRVLDAGAPGLHVYTFNQYRPALDLLE
GVHLGGTPSDGVDLARRPWVPSIPAV
>A0A2S0MAJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ottowia oryzae|TrEMBL
MTTSLSLEFFPPKTPEGADKLRAVRQKLYALAPEYCSVTFGAGGSTQEGTLDTVREIVGE
GYAGVPHLSCIGQTKDTIRQRLASYRDAGVKRIVALRGDLPSGYGLGGEFRYASDLVTFI
REETGEHFHLAVAAYPEVHPQAKSPQADLDAFIAKVQAGANTGITQYFFNADAYFRFVED
LRRRGVETPVVPGIMPITNSSQLLRFSDACGAEVPRWVRSRLQSFGDDAAAIKDFGADVV
TALCRRLLDGGAPSLHFYTLNQSVATLEVLRRLGIA
>A0A3B0SZV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MRGWKGGAAPKVSFEFFPPNSEKMEARLWDSLRRLEPIGPEFVSVTYGAGGSTRERTHRT
VTRILAQTGLRAAAHLTCIAASKTEIDDIVQRYWAGGVRHIVALRGDPTAGAGPGAAPAP
YAPHAHGYANTAELIAGIKKQHDFEVSVGCHPEIHPESPSLAHDLDVLKAKIDAGATRAI
TQFFFEPDTYFRFADAAADAGITVPIVPGIMLQPNFSGLKRMAAMCRTHLPRRIADLFDG
LDDDPETREALTAQLAAELCNGLATGGVDHFHFYTLNRAGLALATARLLSLTSQNRNAA
>A0A3B0UEL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MTATRKSRLPQSQKPEFELSFEFFPPKTEKAEERFWHSLEKLIPLAPKFVSVTYGAGGST
RERTLKMVSRISSETGIDAAAHLTCVGATKEEVDEVVRGYYDAGVRRIVAIRGDPEAGIG
EKFIPHPGGYASSVDLVAGIKNIADFDVSVAAYPEMHPESSSWDEEIENLKRKEDAGASR
ALTQMFFDNNDYWKFLERVEKAGVKLPIVPGIQPIHNFERISFFANKCGAKVPTWLAQRF
AGLENDPGTQALVAASVAAEQVTELMDGGVTQFHFFTMNHAAQVMALARVIGQTKK
>A0A1G3F3P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium RIFCSPLOWO2_12_FULL_59_450|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A150P4M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
MVTKSKMERLLCERRFLVSAELTPPRHHDLEKLLKHARNMADHVDVVQINDHLLSQARCA
NMAVGHLVKQQGLEPVLQFSLRHKNRIALQGDLLGMAALGLSNIIVLGGYPCAIGSDPDA
KEVSDVDSLKALELTSRMTREGKLFNGDVMSPAPYFHVGTIDFPCGEQAIAGAMDRLTAK
IDAGASFIQVQAVFELAPMRRWMAAVVERGLHERAHFIAAIFPFAGVDRLSFLQKVPGLV
VPDHLIERVRLSGDAEGESYRITLELIRGLRDVPGLSGIHMRSIGAEDWVPRLVEEAXVP
RLVEEAGLRQAA
>V7HGE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L103C120A0|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHDDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A5P8RP68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pestis subsp. pestis bv. Medievalis|TrEMBL
MERKLSFEMNSAKNEKEMENIFKLIEFTDTLDPIYYTVNTEIGSSVWSDTYRTVIELREK
TDVPLIPHITINNKKEREIMQIIEKYINVGICEFFVIRGDKHVYDQDNPINYGVELIELI
RRSHKHIGIKTSLYPDFHKETTEVKEEIDWNERKYQLGVNEFISQLTLNTNALDFLSHWV
DKERPFTPSIMPLGNFSFIEKFTSSNSIDYPLWIKKFANSKSNSNEDKENIGIEIIRFLC
REYLNQRERLHVFTLNKVDVMKKIFQ
>A0A6G3AFD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID2999|TrEMBL
MAGALLDGASLEMTGKDVPRLAEARAALDGGTRINVTYLAGEDAGMRLAAARAVREHGFV
PVPHLSARRLPSSTELERFLAGLAEAGAVENVFVVGGDPARPEGPYEDALSVIRGGLLQR
YGVRHVGICGYPEGHPAIGDDALWSALTGKAAALKAAGLGGEVITQFGFDADAVLTWLEA
VRGRGVHLPVRVGVPGPAGVRRLLGYATRFGVSTGASVARKYGLSLTNLMGTAGPDRFLD
DLAGGYDPARHGTVKLHFYTFGGLRPTAEWITGYRRERG
>A0A1I4REX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulforhabdus norvegica|TrEMBL
MKAGSRLEKILSSGQFAVTGELGPPRGADVEVIKKKAEHLRGMVDSVNVTDNQTSVVRMC
SMAVCKLLLEMGLEPNLQMTCRDRNRIAIQSDLLGAYALGIRNVLCLSGDHNKFGDHPQA
KNVFDLDSIQLIQTVKQMRDEGKLLSGQECEGVPKFFIGAAANPFGDPFDFRPIRLAKKV
QAGVDFIQTQCIYNMEKFREYMKRVVDMGLAEKCYILAGITPLKSLGMARYMANFVPGLD
VPDYYLKRLAGVEKKKQAEEGIKIAVEQIQQVREIEGVAGIHLMAIEWEHRVPDIIKAAG
LYPRPEVN
>A0A7X3ABE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. NEAU-GSW1|TrEMBL
MFKQKILNKKSGILTYGMTPPKAANSPERIAEIAQLQIDRLKELDIDALILYDVQEEAER
VDQERTFPYLPTIDPATYSDHYLSQLEIPRIIYRCVGNYTETQFKDWIKADINRDKFSVY
VGASSSKQEVKLDLPSAYTLSKQLNNNLTFGGVIIPERHILKNDEHIRVVNKIKQGCDFF
VTQATYNVEASKNLLSDLYYHCTNNGIEMVPIIFNLAPCGSTKTLEFMKWLGISIPKWLE
NELKYTNDLLDKSIHLSRKIFEELLDFGLEKGIPIGCSIESVSTRKSEIEASIQLMSDIK
ELLDKKMKKVEFSVR
>A0A7J0AWM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium|TrEMBL
MRVIDHLQANPGRTAFSFEILPPLKGNSIEKVYNIIDKLRDFDPKYINITSHHSEMIFKE
MPDGSFRPQKMRKRPGSVAIASAIQNKYGITAVPHIICKGFTRDETEYALIDLNFLGVHD
LLLLRGDIKGPEKSDDPTKINRHATDLQAQVNDFNRGIYADGETFEPNATPFSYGMACYP
EKHEEAPNMDSDLYYAKQKVDGGADYLVTQMFFDNSKYFDFVERCRKAGITVPIVPGIKP
VVFANQLNVLPRVFRSDIPEAFASELRKCKDDAEVREVGIEWCIGQCRDLIAHGVPSIHF
YTLMASESVRRIAKEIY
>A0A495XYM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terracoccus luteus|TrEMBL
MAHGTASSMVRAERFTRSIPEMVQADAPTFSFEFFPPKDDAAATTLWEAIRRLEKLSPSF
VSITYGAGGTTRDRTVRLTQRVLESTSLTPLAHLTCVGHSRDELRRVVGQYAAAGVHNIL
ALRGDPQGGLGEPWTPHPEGFDHADELVAFIRSLGDFTVGVAAFPDGHPESRGVADDAEA
LVRKERAGAGFAVTQMVFDVENYLRLRDEVARRGSSLPVIPAIMPITNARQVVRMAELAG
QPMPTAVTDRLGRAGDDPAAVRAEGLAIATESSRRLLDEGAPGIHFITMNRSSATLEVFG
NL
>A0A446A5A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. JV551A1|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A097ATJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter kivui|TrEMBL
MGLLEEKLKSGEFVVTAEMAPPKGIDMTHFKECAKAVKGRVAGVNVTDFQSAVVRVSSLG
AAVILLEEGLEPIMQITGRDRNRIAIQGELLAAGALGIKNVLALTGDHPMFGDQPGAKPV
YDCDSVNILMIASKLMEGQDWAGNQLNKAPEFFLGASVTPLFDPLEAQIIKMKKKMQAGA
KFFQTQAVYDIEVLRKFREATKDLNAKVLVGVIPLKSPGMANYMNKNVPGIHVPDALIER
LKGAENKVKEGLKIAAEFINQVKEEKLCDGVHIMAIGAEENVPILLDMCNL
>C8RXU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter sp. SW2|TrEMBL
MTTPRISLEFFPPQTLEASFRLWETVNVLAPLKPTFASVTYGAGGTTRKLTHEAVTTIGR
NYGLNVAAHLTCVDATRAETLEIAAAYAEAGVTEIVALRGDAPKGAARFTPHPEGFANSV
ELIEALAATGNFTLRVGAYPEPHPDSADSAADVAYLKRKIDAGASSAITQFFFEPETFLR
FRDACAKAGIVAPIIPGILPIENWAGARKFAARCGMQVPQWLDDAYAVAKRDGREDLLSV
ALCTEMCDTLIGEGVRDLHFYTLNRPHLTRDICHALGVAPDVALENVA
>A0A1P9WVH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma montaniterrae|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPIKGDNLKSLLDNIEPLMEFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFTREETEDFLIDLHYLGID
NALVLRGDPAKPFTTFKPKENGYAYASELVEQVANMNRGVYLHEEDTALAPSNFCIGVAA
YPEKHFEAENHDIDFEYLKQKVDRGADYIVTQMFFDNGKYFDFVDRCRQHDITIPIIPGL
KPLSTRKQLQILPKIFHLEMPADLVRAVEACENDQQARQVGIEWSIQQSRELVAGGAPVL
HFYTMGKADNIMKIAREVF
>A0A2P5YZJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sacchari|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
RFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQAHDALSDLRHFKTKVDAGADAAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAEAIREFGADVV
AALCQRLIDGGAPALHFYTLNLAKPTTSVLARLPSAVG
>A0A7R7E8G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. J8|TrEMBL
MTALQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAQRLDHILHDEITETQVDMVK
TAH
>A0A371XFR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium denitrificans|TrEMBL
MAKRPVHIDENPEGVHLPLEPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNR
AKVFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGG
AAMGVANILCLTGDGVQAGDQPGAKPVFDLDSISLLETIRIMRDNGKFLSGRKLTTPPQL
FLGAAVNPFAPPFDFRPLHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFV
LCGVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAEDQKKEGKRICIDIINEVKEIAGV
SGVHVMAYRQEEYVAEIVDESGVLKGRRPWQREARQDDRMVAERLDEILQKNKIETQVDL
VKTAH
>A0A1C6RG51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora nigra|TrEMBL
MALGLPSVLPNPQPAIGELIRDCRPTFSFEFFPPKTAPGEVLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVALTERIATETTLLPMAHLTAVNHSVAELRNVVGRLAAAGVRNVLAVR
GDPPGDPTAEWLPHPQGVLYAEDLVRLVRAAGDFSVGVAAFPYKHPRSPDIDSDTAYFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILPGVMPVTQIGTIARSVQLSGAPF
PAALAARFERVADDPEAVRRLGVEQASEMCARLLAEGVPGIHFITLNRSTATREVWQNLQ
VGART
>A0A068RAG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus poinarii G6|TrEMBL
MGAQGMSFFHANQREALNQNLAELEGQIRVSFEFFPPSTAEMEQTLWKSIDRLSKLKPKF
VSVTYGANSGERNRTHSIIKDIKEKTGLDAAPHLTCIDANREELRNIAHDYWQNGIRHIV
ALRGDLPVHCGKPEMYGADLVALLKAEADFDISVAAYPEVHPEAKSAQADLINLKRKIDA
GANRAITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATLTNVRIPNWM
TRMFEGLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A3S8U4M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tabrizicola piscis|TrEMBL
MAPQSAPRISFEFFPPQSLDASFRLWETVQALAPMKPSFVSVTYGAGGTTRTLTHEAVST
IHRNYGLPVAAHLTCVDATKTETLSIAESYAEAGVTEIVALRGDAPKGAQRFVPHPMGFA
NSVELVEKLARTGKFKIRVGAYPEPHPDAADSTSDVTWLKRKIDAGASSAITQFFFNADT
FFRFRDACVKAGITAPIIPGILPITSWAGAKRFAARCGTQVPAKLDEAFATAARDGREDL
LALTHCTALCDRLLQDGVEDLHFYTLNRPHLTREVVRALGITPDVVLEKVA
>A6ZWM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain YJM789)|TrEMBL
MSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKT
LALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVE
AGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
AILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETVANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVAKASA
>A0A800BTR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bipolaricaulota bacterium|TrEMBL
MRAGSNLEKILELGQFALTCELGPPRGTSRRAIETKGELLRDYCDAINVTDNQTAIVRMG
SLPSCVILREMGLEPVLQITTRDRNRLAIQSDLLGAVALGVQNVLCLSGDHPRLGDHPQA
KGVWDLDSIQLIQALKQMRDERRLLSGNEIRGEVPLFIGAAANPFADPFELRVLRLEKKI
EAGADFIQTQAVFDLPRFKRFMEMVRDRGLDERVHILAGVIPPKSAGMARYMRDYVAGVL
VPDEVVRRMEDAKDAKEEGIAISLEIIEQILEIPGVHGIHIMAVGWEEVIPEIVSRARLL
PRPIV
>A0A7X7T1B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter sp|TrEMBL
MSLSRLSVELIPRSAEALATDVDTVKATFSVADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQPGLEEILVVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMQGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLDANIQFAQTVLKELAQENGKAYLMPVRIKLEQY
LPHLLDAVA
>A0A6L9VY67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus saxobsidens|TrEMBL
MNRALTVRDPNTRATLRRSFETLGYEVIPFKKTQEQVLQHVPKDVRLTVTASPAKGQDVT
IDLTVALAGHGYHVAPHLSAQQVQSRGHLADIVARCREAGITDVFVVGGDPTDTPTEFKD
AHALLVALHELDHGFTDIGIGGHPEGHPSVSEDVLFQALKDKASLANHIKTQIVFDPAVI
LRWARELKRRGIDLPVHVGVPGAVSRQKLLRVSGGLGIGESAKFLKKQQTLLWRFFVPGG
YNPAKIIKGLAPHMGKPDNTITGFHVFTFNDLEPTEEWRKQTIQGLA
>A0A8J6YAC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfomarinibacter sp. MAG AM1|TrEMBL
MTHENNLSQLQGRLQDPCFEIIPLKGIEKKVHHIPTGSDVAITCSPDKGIPATLELTRHL
RDHGFNLIPHIAARMVADESHLREILGELDELGIHRIFVIGGDAEEPAGEFDSSFQLLEL
MSTIDHSIDTVGIGGYPEGHPLIDEKTLLQFLKKKQKFAVYMVTQM
>A0A8J3IIB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reticulibacter mediterranei|TrEMBL
MTHPLLEQLQEGPVLCDGAMGTLLYARGITYEQCFDALNLTQPDLIQRIHGEYISAGAQI
IETNTFGANRAKLEAYHLEERVREINFRAVRLAREAREIAGQPVFIAGAVGPSGRPLQAP
NEQRLSELRTIFREQIEALLEGGVDLLILETFSNLAELRQAVLAAKEVGGLPIVAQMSYY
EDGHTLSGQSATRVATVLSDLGIDVMGANCSVGPAATLDALQEMIIAVKQQLDGAGPTLF
SAQPNAGLPARIGNRFFYVATPDYFADYALHFVEAGVHLIGGCCGTTPHHIAAMRKVLDE
QYGTHTQFAAAVQLQQQPVEQKQSSNGQVIVAKLIEEQIILPQQGSMTQLQEKLAAKEFV
VSVELDPPKGLNPHKILEGAVQLQNAGVDFINIADSPMARVRMGCLALARLIQDHLDIET
IIHFTTRDRNLMALQSELLGAHALGIRNILALTGDPLRVGDYPNTTGVWDVDSVGLIRVI
RDMNDGHDAAGSSIGARASFHIGCALNLNMSDEETDREIEKYRQKLDAGAHFIMTQPIYE
IAPLQRFLDRAGKPPIPMLLGCIPLHSSRHAEYLHNEVPGITIPDDVRARMKAAGEHGHE
EGLKLAQELLEEASGQVEGVYLMPSYGRYDVVSELTKALHTQKRPDRTG
>A0A385N7P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WCHA55|TrEMBL
MSKKIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDLDIQRFCDKANAGANAGLTQFFFNPDAYFYFV
ERIQKEGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A0S8AKR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium SG8_35|TrEMBL
MLVKDILHSKKICISYEFFPPKLENDWDMLFQTISDLIPLEPAYVSVTYGAGGSTRDRTH
DLLVRIQEETDLTVVSHLTCVGSNRDDIHAILRKYDDHGIENILALRGDLPKGQTQWVQP
EKGFAYAADLVAYIKKHFPRMGVGVAGFPEGHPDTPNRLKEIDYLKAKVDAGADYIVTQL
FFDNRDFYDFCERCELARINVPIIAGIMPITTRQSMVRMAELAAGARIPARLLKSVERAG
SDEYVERVGVHWATEQVRDLIDNNVRGIHLYTLNCSTATLRIYKSLGISSSTQLSM
>A0A4R1Q1W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerospora hongkongensis|TrEMBL
MSTLQNKLAAGRFTLTVELDPPKSADAEKTIIEAKQLKDRIDAVNIADCPMANLRMSPIA
LSHVIQADVGLETIFHLTCRDRNIIGLQAELLGAAALGVHNILALTGDHPQQGDHPQAKA
VFETDSTGLIELAAKLNNSQDIMGNELHKGTSFFIGTAVNPGAEDLDKELEKLTAKITAG
ARFVQTQPVYDLEIAKRFMEKVKNLPIYVLMGVLPLKSHKMALYLHEKVPGITIPPVIMD
RMAAGGKAAGLEIAAELVRGTKNIAHGVHIMPLNDIQTVVALTDQL
>A0A3Q9BZI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces aquilus|TrEMBL
MGAAGLRALLESVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLELAGRLAAH
GYRVVPHVPARLLRDDAHLKDVVDRLAEAGVADVFVPAGDADPPAGGYDGALPVLRRLGE
LGSPFARVGVTGYPESHPLIHDDVTVQAMWDKREHATYIVSNLCFDPRVLGEWLVRIRAR
NITLPVHVGVAGPVQRAKLLAMATKIGVGESTRFLTKHASWFVRFATPGGYAPERLLSRA
EAALTAPSAGVAGLHLFTFNQIAETEKWRRALLDRLGA
>A0A345Y6D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenobacter cavernae|TrEMBL
MTLPISIELYPGINPAGAARSAELASRLAPLAPAFVSVTDGAGGISRAAGLALSDALNAQ
GFAVAPHLSTAGLDQATATERLAEFSDRKAKTLFALRGDTPSGMGERGDFRYASDLVRFM
RETLGDGPDILVAAYPEVHPQAKSAHTDLAALKAKQDAGATGAVTQYFYNADAYRYFADA
AVRAGVTLPIVPGVLPLTRVSMARLAEVRGVELPRWMKRALDACHGDAAALASFGREVGA
RLVSQLIAAGAPGVHFFAPGAAEIEMASLILADTGLTPPKAA
>A0A510JBV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoleptotrichia goodfellowii|TrEMBL
MKIKDLYENKNPVFSFEIFPPNKNFSEEKLKAVTKELASYKPDFISVTYGAGGTTKAGTV
EIASYIKNELKIETLAHLTCIGSKKQEIANFLKELKNNNIKNILALRGDIPQGEDESIYN
RGDYKYASDLIKDIKENEDFSIGAAFYPETHYENNDLIDLFHLKEKVDLGANFLISQIFF
ENETFLRFREQAKKLSINVPLVAGIIPVTNAAQIKRITALCNSKIPSKLEKILDKYGSNP
DSMKKAGIAYATEQIIELLSNDIRGIHLYTMNKTDTTKEILDNVSFVR
>A0A533TXK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium sp|TrEMBL
MLVKDILNSAVKPVFSFEFFPPKKDEDWETLFETIAALSPLNPSYVSVTYGAGGSTRSRT
HDLVVRIQKQTGLTVVSHLTCICSSEEETGTILQNYLDNGINNVLALRGDKPAGIATLEE
AIKDFPHSIDLVRFIKKNFPSIGVGVAGFPEGHPETPNRMQEIEYLKAKVDAGADYIVTQ
LFFDNRDFFDFVERCAIAGITIPIIPGIMPVTTRKGMIRMSELALGARIPAPLMKQVLAA
GNDTEVAAIGIEWATRQVQELIDNHIRGIHFYTLNMADATLRIFRNIHE
>A0A511NBM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus cellulosilyticus NBRC 106333 = KACC 11606|TrEMBL
MQAGDLPEFEPFRAVLPHRGLDFSLENRSGVSTLWSMRIAVELVPKTFEHLQEELSYIQQ
HLPRVDTINLPDLMRYDIRSWQACRPVQQILPSNSAIPHFRSIDLNVKKPLPFADQLLES
GVREVIVVTGDPPTDMSRKVYPTSCIDAIRKFKRELPEIKVYAGLDPYRSSLRSELEYLE
RKQEAGAEGFFTQPYFDLRLMGVFQEMFEQSECRDLPIFWGVTSVVGERSRRYWETRNRA
IFPKDFQPTLDWNRAFVSQALHWVEENRGNIYFMPIRVGIADYLSGLL
>A0A1V6H4P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium ADurb.Bin070|TrEMBL
MKRKQENGADFAVTQLFFDNAVYHDFVAQARAAGVTIPLLPGIMPLSSARQIERFVALSG
CSIPDTLRQAAAAEDVEEAGFRFALEQCRDLLARGAPGIHLYTLNQSSLSGRILAALRAE
NPGL
>A0A1B2JA24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataella pastoris|TrEMBL
MTKIIDKIKELKGEPFYSFEFFPPKTDNGLRNLLARLGRMSMLNPLFVTVTWGAGGTTSN
KTLDLAITCQKDLDLTTCIHLTCTNTSKKLIDNALKTAYDNGIKNILALRGDPPREAQEV
VVEQDFKYAIDLVRYIREQYGDYFCIGVAAYPEGHVEGNDDSEQSIEHDMPFLLEKINAG
ADFVVTQLFYDADKFCTFYNTLKQHLGRDVIVIPGLMPINTYQLFQRATNLSHASIPPAV
GQLFPPDVRHDDDKVKDIGVKLMIDIVDQIHKETHGQVSGYHFYTLNLEKSVAQIVDKSD
HLSPRLTVSSRFENAIESSSEDEKEQNQQTKTIIAISSGEGTMGKEATWDDFPNGRYGDS
RSPAYGEIDGYGPSLKVSSSRAYKLWGYPVDLDGITDIFIAYLSNRITALPWSELGLNPE
TALIQEELIQLNEKHMFTISSQPSANGVKSTDKLFGWGPSEGYVYQKAFVEVFINKKQWN
EEIFPNLQEHKSVTWYLGDCNNAFDTNIKIPLSSNSVTWGCFPDKEIVQTTIIGEESFQA
WNEEAFNIWREWQKLYPKNTASYNLLGSIINDFYLVTLINHDYANDNNNLWEILLQ
>H6RSW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus saxobsidens (strain DD2)|TrEMBL
MTPTVRELLATGRPTWSFEFFPPKTPAGEEQLWTALRELERLRPSFVSVTYGAGGSTREG
TVAMTERIAAETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WIAHPAGLRYAAELVELIRSIGDFCVGVAAFPERHPRSPDVDTDVDMFVAKCRAGADFAV
TQMFFRAEDYLRLRDRVVARGCDVPLIAGVMPVTDVRQITRIVELSGQAFPADLVERFAE
LDGERPEDKAAVRAYGVEVATELCRRLLDEGVPGIHFITMNRSTATREVFTNLAPDRS
>A8LY71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinispora arenicola (strain CNS-205)|TrEMBL
MALGLPSILPNPQPAIGELIRDRRPTFSFEFMPPKTAQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRHVIGRLAAAGVRNVLAVR
GDPPGDPTGEWIPHPDGVHYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDAATDTAYFVR
KCRAGADFAITQMFFDADEYLRLRDRVVAAGSDTPIIPGVMPVTKISTIERSAQLSGAPF
PPTLAARFERVADDPEAVRRLGVEQASEMCRRLLDEGVPGIHFITFNRSTATREIWRNLR
AGDTE
>F4QHQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asticcacaulis biprosthecum C19|TrEMBL
MAPIARSLSQTSGNLKVSFEFFPPKSEEMEETLWASIARLAPLDPDFVSVTYGAGGSTRE
RTHRTVKRILDETALKPAAHLTCVEASRDEVDEVIREYWEAGVRHIVALRGDPPSGWGDY
TPRPDGYQNATELTAAIKRIGDFEVSIGVYPEKHPQSPSLDFDLDVLRAKVDAGATRGIS
QFFFEPETYLRYRDAVFDAGIEIELTPGIMPVTNFKGLRRMAAACEAQVPQWLESLFAGL
DDDAETRKLLASAVAVELCLELEREGVENFHFYTLNRADLVFAICRILGLKAAAL
>R5ZGJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. CAG:166|TrEMBL
MRVDELFKQAASQGTAPVSFEMFPPKGELTLDTARKVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAAHQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A382EPY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKISDKLEDFKAQGKTYYSFEFFPPKTDFGLDNLYSRIDRMASLQPAYIDITWGAGGSTA
DRTLEMSKTIQKYFGLEVMMHLTCTNMSVSSINKVLMDAQENGLSNILALRGDPPEGTGE
WEKHEQGFKYGIDLVRYIRKEFGNEFFLGVGGYPDSHQEQSDIDVDISYLKEKVDAGSDI
VITQLFYDVDKFLAFRDKCSTIGIHVPIIPGIMPIHNYARFIKFTQFCKISIPKSVTETI
ESIKNDDSSVINYGIDQATSMCEKLIAEGVPGLHFYTLNLEHSVSEILHSLGLASTQGSV
RELPWRQSTAGNRKTTEDVRPIYWSNRPVSYLTRTETWDDFPNGRWGDITSPTFGELNQY
HAIRAGSKSDKVKARKKKLWGEPKSIKDITKVFVSFCEGKINNLPWCEIPLAIESKQISK
ELVKLNELGFLTINSQPNVNGASSEDPDVGWGAAGGRVYQKAYLEFFTSKDKLDKLLETM
DSLDNISF
>A0A381PH35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MHIIDKINQRIREKKPFYSFEYFPPATEAGLHNLYARIEQMVALEPIFVDITWGAGGSTN
EKTLGIAENLQKFFGLDVMMHLTCTNMPIEQLDEVLEKARAAGIRNILALRGDPARDSSV
WERVEGGFTYAYELVSHIRARFGDEFCIAVAGYPEGHLEAEDKDTCTGYLKHKVDCGADF
VITQLFFDINEYAGFLERCD
>A0A381SZ40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKLIDLYNKKDFVFSIEIFPPKTDKGVEKLKSTLKGFRQFAPDYMSVTYGAGGTSRENTH
EMAVHINHELGIPAMAHLTCVSHTADEIDKVLTSLKNRNIENVMALRGDPPVGTDRFVRP
EGGYQYASELISAIRKHSSFAIGAAGYPEGHVENPDKEEDRIHLHEKIACGAQFIISQFF
LDNIHFLRWRDLLRHEGVALPLIAGILPPTNWHSLQSMSAMCGVSIPKQLAQDLIKQEDD
PEVCREIGFDHVERQLEELLSEGVEGVHLYALNRLETVERLGPQLQKASGESLNAVTV
>A0A7V9R800|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MRTNRRRQSLAPLLRNARLEVLPTPTAEQRVTENVAVGRTITVTASPNRGLEATLDLAER
LAGQGYQAVPHLAARMVSGRSELVEITERLLAVGIYTVFVPAGDADSVAGDYASSVDLLE
DLAAIGRPFADVGVTGYPESHPMIVDDVTVQSMWDKRRHATYIVSNMCFNPRVLRTWIVR
IRKRGITLPLLVGLAGPVERAKLLAMATKIGVGESTRFLTKNRSAVAKIASPGYSPERLL
DKTAATLTAPESLVTGLHLFTFNQVAEVERWRARLLAAAEDGSLVG
>A0A7W2B0M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MINSNLNNSTIQKSFEIVPPRYSISDSFINKIIKHEKSFDLLDITCCPMATLRVNPIAVA
HRLILKGIKPEKLIVNFSSRDRNSLALQSEIFGALSIKLKNILIVKGDPIRYGNSKNSKE
VFELTTDQIINKVNNINKGFDFNNNETNSKNYIDIFSTLNINRSFNEIKKTIQKRLRKGS
KFFITQPIYSESDFEKIIKLSKSKDYKIFAGILPIKNKKILGNLLKKLGGITIDSPHLVE
LAKYDDKKIHSHSSKHLKKLIKVYKKNLDGLHLMTSGSINEASNLIKDL
>A0A382I7Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MIKDISFEFFPPRTEKMEQNLKQNIGKLMELSPKFVSITYGAGGTTRDKTHKIISKLISE
TDLNVAAHLTCVNSSVNEIDEVIENYTSIGVKHIVALRGDMKDLGQFTPHPKGLN
>A0A2B4SGV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stylophora pistillata|TrEMBL
MSQQGSEREPKPEKLIDTIRCKMAKNEQFFSLEFYPPKTFNGATNLMAILGRLHEHCTPL
FCDITWKPSQEPMSDKCQSEPSSLLVSAAMIDLYGQNIMIHIPSRNTTRSQVLEHLTRAK
NLGIGSVLAVRGGTAWPFHFQDLLLILFAVC
>A0A7V9TT15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MVTGRHARTLERPAMLRELLARPGHSYSFEFFPPKDDDGERRLWQAIRELEPLDPTFVSV
TYGAGGSTRDRTVRITARIASETTLTPVAHLTCVGHSRDELRSVMGAYADAGVRNVLALR
GDPPGGPGKPWIAHPDGLDHADELVALVRSLGDFSVGVAAFPGGHPEAADLDADARVLTA
KARAGADFAVTQLFFETEPYVALVRRVEALGCPIPIIPGIMPITDLKQIHRMAELSGTSV
PGWVVDRLGELSDADDVRAVGIELATMLCRELLDAGAPGLHFYTLNRSTATRQIFASLRR
S
>A0A7V9T7I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MATALTIRPRLREQLGSGQRSFSFEFFPPKDDTGERRLWTAIRELEPLDPTFVSVTYGAG
GSTRARTVRITARLRERASPRLTRRAIRPDPSPNRSEVSWCVVAYQGAGTAILADMRVRP
SVGKVSLGLVAVVAGLGCCVLVGALALELLAADVRPRAVLAAWSAGITAVVLTILALQEH
GDPDDDPRYFATLVHGLRQEWHR
>A0A382DQB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKVTEHLNKTKQTLFSFEILPPLKGTSIQSIYDALDPLMEFNPPFIDVTYHREEVVYKKR
ENGLLERHAVRKRPGTVGICAAIMNKYQVDTVPHIICGGFNKEETENALIDLDFLGIENV
LVIRGDPITSETYFSPEINGHSYASELLAQVDNMNNGVYLDEELKDSAPTDFCIGVAGYP
EKHFEAPNMRSDIHFLKKKVEAGADYIVTQMFFDNQKYFDFVERCRKNEINVPIIPGLKP
IATKNQLTLLPQRFYLNLPEQLVEQLIKCKNNDAVRQVGIEWAIQQCKELIDFGVPCLHF
YTMGKSDNVQKIVGSLV
>A0A382Y5W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKISDTINDFKAQGKTFYSFEFFPPKSDYALDNLYSRIDRMASLQPAYIDITWGAGGSTA
KRTLEMSKTIQKYF
>A0A6H9V0X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces luteolifulvus|TrEMBL
MALGTASTRTDRARTVRDMLAAGTTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVRATEQIAADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPRGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDTDVTHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCVTPVIPEVMPVTSVKMLERLPQLSNAMI
PAALKERILTAKDDPAAVRSIGIAFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A8F7RAS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus velezensis|TrEMBL
MGLLQDLKERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIADLGADIAGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTEKEVKIRREEEVI
SVSNERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A383CPA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MQSGSKNLSFEFFPPKTDKGKEKLKAVIEKLKVFSPEYFSVTYGAGGSTRAGTLETCITI
KEKNELACPHISGIGSSKKLITEMLDEYKANNMQRIVVLRGDLPSGSVGHG
>A0A382SBE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MSNLQEKMANGFVVTSELVPPKGTDIQSLLKTARLLEGYVDAFNVTDSHSARMRLAPVAA
AHMLIDHGVEPILQMVTRDRNRIAIQSDMLGADVLGITNLVCMGGDPPHIGDHPDAKPVY
DLSSHEVISVADTLNKGSDYAGNQLNQATNLHIGAVVNPGATDLETEIGRMEQKADAGAR
FFQTQAIYDVEGFQNFMNAVSHLKVTVIAGIMPIKSVKMAEYANKNIPGI
>A0A7L0L266|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sylvietta virens|TrEMBL
MVNETQQSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRYLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A316D9R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tumebacillus permanentifrigoris|TrEMBL
MNRQHAFRARLRSDILVGDGAMATLLYLQGNAIGASTEELCLTEQDWVRDTHIAYLDAGA
TVIETNSYAANREALARYGLETRTTRINRASVQIARQALEQTGRDAFVVGSIGSILAGRV
RGTAWEEYRDVYEEQAVALLHEGVDGVILETFYDVEELLLALDVIRPLAASSGTPIIAQL
SLIEVGRTRDGYELTQAFRQLESAGADVVGLNCRLGPAEILGSLERTIVPEGMPISVYPN
AGRLGMIDGKVQYKSNAAYFGDYAGRLVNQGVSLLGGCCGTSPEHIKAIADSVAGRRRVT
RVNPVLAERVVPVERETPRIEIPPTPSIVDLVKQRHTIIVEYDTPRDLDIEKYITGSRAL
QEAGADAITLADNSLATTRVSNMALGAILKRELGIEAMAHVACRDRNLIGQQSHLLGLHA
LGLNQVLVITGDPARVGDLPGATSVFDLSSFDLIRMVKQLNEGIAFSGRRMKNQARFVVG
AAFNPHVRNLEPAIARLERKVEAGADFIMTQPVYDVETLLAIREATRHIPIPIFIGVMPL
TGQRNAEFLHNEVPGIKIAESTLERIKRFEGEAARHEGVQIAKELLDVAVHHFNGLYLIT
PFNYYDMTVELTRYARQITSAQAEIAVGREHQHHGSGCC
>A0A381NW06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKVIEHINKAKGKTQFTFEILPPVKGHHISSIFDNIDPLMEFKPPFIDVTYHREEYVYND
IGNGLLQKKVVRKRPGTVGICAALQNKYNVDAIPHILCGGFNKEETENLLIDLDFLGINN
IVALRGDAIKSETYFTPNKEGHSYASELVNQISDLNKGIYLEDLEISSKTDFCIGVAGYP
EKHMEAPSLESDIHFLKKKIKLGADYIVTQMFFDNKKFFDFVEICRKEGINIPIIPGLKP
ISTLKQLNILPQRFHCNLPEELIKEVIKCKDNKEVKEVGIEWCIKQSKELKKAGVPFLHY
YSMGKSMNIKRIASKIF
>A0A654KZU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain MDR-ZJ06)|TrEMBL
MSHVSPCFQQNQFFMLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVK
TGKEFTPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A436JJQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.04.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A1M3M8U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paludibacter sp. 47-17|TrEMBL
MSIVNRITTAGKTAFSFELLPPLKGNGIESVYRTIDTLREFDPKYINITTHRSEMVYKEL
PGGLFERVAERHRPGTVAVAAAIQNKYHIPVVPHILCSGFTPEETEYVLIDLQFLGITDL
LLLRGDKARHDKSFIPTGHSHATELQAQVNRFNEGYFYDGTKLRSAVQPFSYGMACYPEK
HEEAPNLDSDIQYAIQKVNAGAEYLVTQMFFDNRKYYDFVGKLRAAGVQVPVIPGIKPIT
LMNQLTVLPKIFHTDIPEDFAVALRSCTSDEQAVEVGIEWCTAQVKDLIAHGAPSIHFYT
MMATQSVKRVAKAVF
>A0A0B0I7A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. P1XP2|TrEMBL
MLRHDAGPYRSDRQALAEYVPQPAVYEPIPEPEAPLTVCEPEPETPSGNREPNLVELAKQ
RHTVIVELDPPRDLDISKFMKGAHRLKEAGADALTLADNSLAVTRMSNMALGHLVQVETG
LRPLVHIACRDRNLIGTQSHMMGFDALGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEII
RMIKQLNEGIAFSGKPLKQKAKFVVGAAFNPHGKHLDKAVARLERKIAAGADYIMTQPVY
DPELIRAVGEATKHLDTPIFMGIMPLASGRNAEYLHNEVPGIQLSDDVRSRMAGLEGEEG
RAMGVQIAKELLDVAMDHFNGIYLMTPFMLYEMSAQLIEHVWARSGRQLSPLFR
>I0KC57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrella aestuarina BUZ 2|TrEMBL
MTKITEHIRRANGKPIFSIEVIPPIKGDTLKNLLDNIEPLMEFKPPFIDVTYHREEYIEQ
PQPDGTIRKIVTRRRPGTVGICSAIMHRFNVDPVPHVLCGGFNRDETEDFLIDLNYLGID
NVLVLRGDPAKPFKTFKAKENGYAYASELVEQVANMNKGTYLHEEDKPMAPTDFCIGVAA
YPEKHFEAIDHDIDFEYLRQKIARGADYIVTQMFFDNARYFDFVKRCREHDIHIPIIPGL
KPISTRKQLEVLPRLFHLQMPDDLKKAIEACQTDADARQVGIEWSIQQGRELIANGAPVL
HFYTMGKGDNVQKIARELF
>A0A084RH17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stachybotrys chartarum IBT 40288|TrEMBL
MDKITDKIAALPAGGSYFSLEFFPPKTAMGFSNLRVRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQRELGLTTCLHLTCTNMSPRLIDKALEDAKALGIRNILALRGDPPRNDE
YRDPDEDLDDGRERFTWAVDLVKYIRETHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVDKVQAGADFIMTQLFFDIEAYDKFEKILREHPSGAFKTMPIIPGLMPIQSYQMIKRT
TKLSHAKVPESIMARLDAVKGDDEKVKEVGVDILSELVEQIKEVKSRSPGPQGFHFYTLN
LEKAVSFILERSNLIPDPADNEEALVDDETAGPRITVNGSEPPSKHTHSRTSRRHSSVGS
DPHDRVIVESRNPAHPEWEVSGQEAGIPAGGINSRANTLAISEGEGALGREATWDDFPNG
RFGDARSPAYGEIDGYGVSLHMSVTQATRIWGYPETPQDINQLFVKHIRGELTAIPWSEE
ELLAESSSIKPHLTNLNSKGWWTVASQPAVNGLPSSDQTFGWGPGNGFVFQKAFVEFFLP
SAEWATLQEKLRSPDVKDHVCFYAANAAGNFVSSDASGNASGDHAESSTNAVTWGVFPGK
EIVTPTIIEEVSFRAWAEEAFGIWGEWAKVYRRDSGSEKLLNGIKADYWLVNIIHHDYIE
KNALWDLLMQ
>U7D5B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinivibrio alkaliphilus ACht1|TrEMBL
MFNTITQLQDFNPDHVSVTYGAGGTTRSKTHDLVCEIQKKTNLSVVSHLTCVGHSRQEIR
ELLQDYSQSGIENILALRGDPPHGGANFIPAQDGFAYAEELVAFIRQEFPHMGIGVAGFP
EGHPACPNRLKEIEYLKRKVDAGADYICTQLFFDNRDFYDFRERCELAGITVPILAGLMP
ITSLANMRKISELALGSRIPAKLLKSIHRSEEYVENIGIHWAAEQVNDLLEEGVKGIHFY
TLNKAEQIQRICSSIGIVDSDQLNT
>A0A3M0VZF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetothyriales sp. CBS 134920|TrEMBL
MHISAKLNAAHSQGRPTFSFEFFPPKTAQGVQNLYERMDRMHDLGPAFIDITWGAGGRHS
TLTCEMVSAAQTNYGLETCMHLTCTDMGRPKIDEALRRAYKSGCTNILALRGDPPREQEK
WQSSEGGFRYAKDLVRYIRSTYGDHFDIGVAGYPEGCDDQPDTELLIDHLKEKVDAGATF
VVSQMFYDVDIFLAWVKKCRERGITVPIIPGIMPISTHQAFLRRATWTKCHVPEKWYTAL
EPVKNDDGAVKEIGRDLVVEMCRKILDAGILHLHFYTMNLAQATRMILEELNLTPETSGV
PLSKPLPWRPSLGFGRREETVRPIFWRNRIASYIARTTEWDEFPNGRWGDSRSPAFGELD
AYGVGLKGSNESNIKLWGKPSRLRDIADLFANFVEGRLDRLPWSEGSISAEADSIKSDLI
QINRRAFLSINSQPAVDGAPSSHPVYGWGPQGGFVYQKAYLELFVFPSVIDEVMKRLEAN
KNLTYFAVNKNGTLRTNSPDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WSRCYPQGSASRRLIEKMMNQCYLVNIVNNDFHQTHEIFRIFDDLEVADIDQVFETDADQ
SDTTQATTQATTQATTQAKTNGTS
>A0A2E2U5B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MKQSKVNVSFEFFPPKNEESISSLWQNINRLEPLKPRFISVTYGAGGSTRENTHNLVKQI
KKKT
>A0A5B7W8G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MPC6|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAKYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A4CPQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146)|TrEMBL
MKVTEHIANARETLFSFEVIPPLKGRRIDELYRNIDPLMEFKPPFIDVTTSREEYVYIDR
DGLYEKQVTRMRPGTLGICASIKHKYDVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNVM
ALRGDAMKEQKYFEPTQGGHAYASELVDQIVCLNKGQYLHDVVETDDCSDFCIGVAGYPE
KHLESPSLRTDIKWLKHKVDLGADYIVTQMFFDNQKFFEFVDLAREMGIDVPIIPGIKPI
AVKRHLQLLPQVFRTELPEPLIEAVEACKDNKAVRQVGIEWAIEQSRELKAAGVPVLHYY
SMGKSDNIQAIAKAVF
>A0A2E2QY15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MPQKSDKIKVSFEFFPPKNKEAVESLWFNIKRLEPLNPSFISVTYGAQGSTRENTHNLVK
DIKNKTKLIPAAHLTCIGSSKLEIERIAEDYWNSGIRDIVALRGDKPKIQTKDFSDEFKY
ATDLILVLKKKYNFNITVSAYPEMHPDSVSLEQEYDVLKKKVDLGASKAITQFFFDPNFF
TKFLDGAIKRGIKIPIIPGILPVTNCKKTIEFAKKMQCKMPNWLLKMFEGLDSEPETRKL
VAATIVHDQCKILINEGIKDFHFYTLNRADLSFAICHILGLRTLKD
>A0A552GXF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa Ma_QC_C_20070823_S13|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDAAGIPPIHN
>A0A482R9H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon|TrEMBL
MHARCRRQRMDRLAATEPLYVDFVTVGGLENARRALRLCRYAKKVIGLTAVLHFSCADMS
LSDVNELLAEAKRMGVTN
>A0A1E7G7R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. Ant1|TrEMBL
MKLTELFQRGEFVVTAEVGPPKGTNIDHLIDEVNTYLRDKVTAVNVTDNQSSVVRIGSLA
TCKVMQDLGVNSIFQLTCRDRNRIALQSDLLSAAMLGIENLLLLTGDHTTLGDNPQAKPV
FDLDSVSLLHAVRKLEQGEDLAGNKLEGTPPSFCKGAVVSPCSDSVDVQLAKMEQKVKAG
AEYFQTQAVYEPEKFIKFMEQAKQFGVPVMLGIVIPKSVGMAKFMNANVAGIHVPDEMIE
ELKKDKEKTKAGITGVEISARLIRECREYCQGVHIMALGWESKVPDLLAQAGI
>A0A8J2Q8L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cercopithifilaria johnstoni|TrEMBL
MHDGMDPMTSDNKMNVISDCDGFYIGSSRTTDQAVISSDSIISQICDKKWNKSRTDSVSN
GAYVPLRDRIKKRIATGVPFFSLEFFPPKKANSVANFFACLDRFREGNPMFVDIAWHFGS
DPGNINSETSSSSVAAGCLHYCGIDTMLHITCCPYTKEQSIRHLEQSKALGLKNILALRG
DLPRQDENPVLYKYRALDLIRWIKDEYSDYFTIACSGYPAGHPEAPSYRADLLYLKAKVD
AGADFIISQIIFDEKIFENFLRDCREIGITVPIIPGILPIQSYDSIRRIAELSQLMIPDS
ILASLEPIKNDDDAVRNFGIRHAVNLCQTLFTNGSTTSIHLFTLNREVSSREILQRLGLW
PRSPVRTLPWRSFGENHPVRCKEDVRPIFWSMRPKSYVFRTREWDEFLNDRWGNSSSSGF
NDLRDYYLFYLKGQPTKDEQLRMYGERLETFADTQKVFVNFVGQNINENGVEPPSVNGAP
STDPFVGWGKPDGYCYQKAYLEFFTSQANAEFLWNLLPTYSRINCHIVNHDATIDWTNTE
STMPIAVSWAYFQDEAFGAWLNWSSIYAEGTSSRCLLEKIYEYCLVSLVDNDYPESTIIF
DCLAQLVNR
>B3T2F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured marine microorganism HF4000_141F21|TrEMBL
MNFSLEITMKTDLSTLPKVKDVYITQLPGNDFREVASKAEELADLGFNPVPHFSARSIKN
LTELKEYVSRCKDGGVKQALVIGGSSQPIGDFHCSLQLLETGLFEDLKIGIAGHPDGSPD
ISDSDLEKAMIDKKPYADYIVTQWLLEVDPIIKFISKQTLPVYVGITGPLTISNLLKFAS
IVGAKNSLNFLKSNMTKAFDLLKPKDPNDIIEKLKGVTENFHIYTFGGLKETNKWLMDNN
YV
>A2A7F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mus musculus|TrEMBL
MNHQKAKVLPAGHCYPSLGMWASEAGCVRLSVPPSISRNPAMVNEARGSGSPNPRSEGSS
SGSESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRF
DRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCQQRPEEITG
HLHRAKQLGLKNIMALRGDPVGDHWEAEEGGFSYATDLVKHIRTEFADYFDICVAGYPRG
HPDAESFEDDLKHLKEKVSAGADFIITQLFFEASTFFSFVKACTEIGISCPILPGIFPIQ
GYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHF
YTLNREVATMEVLKQLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQD
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLS
GEPNRHGYRVTCLPWNDEPLAAETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDSCLWQVVEDTFELLNRHPTERETQAP
>A0A6A9UX50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Auraticoccus cholistanensis|TrEMBL
MSDVLATADRPLVSFELFPARNDDEQKILWRTVRDLEALGPDFVSVTYGASGSTRDRTVG
ATAAIAQHTTLRTMAHLTCVSQTREELRHTIGAYADVGIRNVLAIRGDMPGGPTVPFEQH
PGGLANATELVRLVRELGDFCVGVAAFPDLHPQARDADLDARILVQKAEAGADFAITQLF
FTAERYLDLVRRVRDLGCDLPIIPGIMPVTRLGQIQRFAELSGADLPDWVVSRLNEVGED
PQAVRRAGIDIATELCEQLLAAGVPGLHFITMNRSLATREIHGRLVGSGVLPTARPAAPA
RPRNAVPTA
>B5CM26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ruminococcus] lactaris ATCC 29176|TrEMBL
MKIIDRLNEDRINISFEVFPPKTDAGFANVQRATDEIAKLDPSYISVTYGAGGGTSKNTA
KIASHIKDDLHVLSLAHLTCASSTKEEVREVIRNLKELGIENILALRGDIPEGMKFPDGD
RFHYAYELVEEIRKQGDFCIGAACYPEGHVENEHKEDDIRFLKQKVDCGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLALLDRFGSSPE
AMMQAGIAYATDQIIDLLANGVKNIHIYSMNKPEVATKIMSNISEIIKC
>A0A0Q7WHA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. Root554|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKTDEMEARLWDTVTRLEPLQPNFVSVTYGAGGSTR
ERTARTVKRILKETSLTPAAHMTCVDATRGEVDSVIREFAEMGVTRFVALRGDPSAGAGA
AYQPYPGGYANGAELVGAMRAIGDFDVSVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
VTQFFFDNDLYERYVERVRRAGIYIPIVPGVLPVHSFKQVANFSARAGAHVPGWLAERFE
GLDNDAQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRAQQPADA
AGSAAA
>A0A397H8C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diversispora epigaea|TrEMBL
MKVIYKIQKAHEEGRPFWSFEYFPPKTQQGIQYLYDRMERMYRLGPEFIDITWNAGGTSS
QLTSEITATAQSVYGLETVMHLTCTNMPKEKIDKALRDAKECGCQNILALRGDPPKGSDR
WEACEGGFSNAIDLVRYIRAEYGDYFGICVAGYCEGHADNPDKDDDLRRLKQKVDAGADF
IVTQLFYDEDLFLIWVKKCRAIGITCPIIPGVLPIQNYTTFKRIVTLSNTSVPQYVLEDL
EPIKHDDSAVKEYGIQLTVKMIKKMYADGISGFHFYTMNLERSTRLILEALEFVAPVENA
KPLPWCPSLSVKRKMENVRPIFWRNRTKSYITRTEAWDEFPNGRWGDSRSPAFGELDGYG
ISLKHSIKEAHRLWGYPNKLTEICDLFVQYCNGEINSLPWSDQTLAQETEIIKDHLAHIN
SLGYLTINSQPAVNGARSDDKVFGWGPKNGYVYQKSYLEIFVSPDKLDTLIPRIARDPLI
TFYAVNKQGDLKTNTQSEGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELWNEWAK
IYEPDSISSKLISEIAETWYLINIVHNNFHDSEGIFAIFEDNYTNDLLDADR
>A0A0Q7IE48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp. Root436|TrEMBL
MLDDNLRASRQTAHQRPELQISFEFFPPKTDVMEEKFWDTVHKLAPLKPRFVSVTYGAGG
STRERTLRMVRRIKAETGVDAAAHLTCVGATRDEVDEVVRGYQEAGINRIVALRGDPPGG
VDQPFVPHPQGYQNAADLVGGLRRIGDFDISVAAYPEKHPQSPDWHSEIDNLKRKLDAGA
DRAITQMFFSNPDYLRYLERARAAGITAPIVPGIQPIHSFKQIASFAARCGTAIPAWLSE
RFDGLDEDPETHALVAAAVAAEQVTELVDEGVTEFHIYTHNRSPLALALGRILGRRHEAE
AVNAA
>A0A3G6WKQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cereibacter sphaeroides|TrEMBL
MARPRISFEFFPPQTLEASFRLWETAQMLAPLKPDFVSVTYGAGGTTRKLTHDAVETIHT
HYKLNVAAHLTCVDATKAETLEIAASYAEAGVTEIVALRGDAPKGVDRFTPHPEGFASSV
ELVEALAATGRFKLRVGAYPEPHPDAADTLADVRWLKRKIEAGATSAITQFFFEAETFLR
FRDLCAKEGITAPIIPGILPIENWSGVKKFAARCGAQVPGWLDDAFDHARRDGREELFSV
ALCTELCDRLLSEGVEDLHFYTLNRPTLTREVCHALGILPEVALQNVA
>A0A3A9K3W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacteraceae bacterium SP2|TrEMBL
MGLKQKLESGGFAVTTEMAPPKGTDFKRFKECALAVKGMVDAVNVTDFQSAVVRASSLGA
ATILLEEGLEPVMQITGRDRNRIAIQGELLSAGALGIKNVLALTGDHPSFGDNPQAKGVF
EMDSVNILQVAGTLMSGKDLAGNDLSGTPDFYLGASVTPVYDPMELQLLKMKKKIQVGAR
FFQTQAVFDIELFKKFINAIQDIDTKILVGIIPLKSPGMANYMNKNVPGIFVPDEIIERL
RKSQDRVKEGLKIAAEFINEVRQQKLCDGIHIMAIGAEENVPALLEMCDLESAA
>A0A846P5A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MNRNFIDELEERILLADGAMGTMLYAKGVYINTCFDELNLSRPSLVSDIHKEYLQAGAEI
LETNTFGANRFKLATFGIEDRVKQINEAGADLARSSANKAAFIAGSIGPLGKPLRPLGKI
SKEDAFAAFKEQAEALAPNVDLFIVETIHSLEEMRIAIEAIKSISSLPIVAQMTFTDEEQ
TLAGESPEQVARGLESYDVACIGINCSIGPQPMLEIIEKMGAVTDKILSAQPNAGSPRLV
ENRFIYLTSPEYMAEYAKRFIQTGVSIVGGCCGTTPEHIKAMASAIRALRPVHVHTHKSL
EVVAEREVLPETPFEQRSRLAASLGKKFVISVEIDPPRGLDPSRPLEAARLMKKSGVDAI
NIADGPRASARMSPMALATLMEKEAGIETLLHYCCRDRNLLGMQADLIGAHALGLRNVLI
ITGDPPKLGDYPSATAVFDVDSIGLVQIVRNLNRGLDLAGNPLGAATSFAIGVGANPGAM
DLETEIKRFYEKVESGAEFVLTQPVYEASLLENFINKTRNVEIPILVGILPLSSYKNAEF
LHNEVPGMQIPKKIRSRMKRTPSGDAARRLGIKIAQEALQDCMTLQAVKGAYIMPPFGRY
ESVLRIIEVL
>A0A3D5FVH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MNRFLDALGAGPLLADGAMGSYIFELTGRLSEPNHVYESFSLDRPEVIRDVYLGYLRAGS
RCLTTNTFAANADCLAVDGLAERLVDLNRAAIDIAREAAEQYRAGEGGEEIFVLASVGPT
TDPDQDDASTFDAYQEQLAAISGADALLLETFRSLASLRQVLSTVAQIPNRPPIIAQMAV
QQDADGWSTSPSELVDAAVAGGAAVVGVNCCTPWDAETFVEQASQLAAVAEGRIRLSAMP
NAGGFQHIGNRYMTRVNPEFMGRWARTMTQRGVSLVGGCCEIHPRHVWEMNNYLAGWGTH
SAGVTVEGAPVKKPSDGRIKRDNGGFSRKIVDGEFAVSVEILPARGTAPKLLQRKIDFVG
GLAASGLADGLDITDGSRGIPLMPPGDFIHVVRERLGWQPGQDGLELMPHFTSRDLNTMG
LQARLVGYWANGIHNVILVTGDPPKMAPSYPPSTAVFDLTSVDLIRLVNNGLNAGVDFGG
QALGKHADPRTRFTIGTGFEPESLDLTAEMEKLTRKIEAGADYIMTQPAFAWEPLEVLSE
VRQSVPVLVGVLVLTSLDHALRMRQVPGVVVPEAVLDRFGQSDDRASQAQVGRDLAAEQI
RRIQSEEWAGVYLMSPASHDPVIDVLRAGLT
>A0A7W1ELZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
MAQDTAIKARDFANDLVACGDIDWISITDNAGGNPQLAPIALGKPILYAGKEVVIHLTCK
DLNRNALESEAWLLHSEGYHNILAMTGDYPLSGSGGSAKPVFDIDSVALIAKLRQMNEGL
ALPARRSDAPATRLEQTDFTIGAVTTNYKLREGEVMPQYQKLRRKIDAGAGFIINQVGYD
SRKAHELRVVMDEGGMSVPLIGNVYVLNPRVARIFHEGRVPGVVVSDALLRLCLAREGDS
DRGRAYFLELAARQMAVFRGLGYRGVYLGGLHNFAATQRILEIERSFAPDDWKEFAREIS
FSRPGEFFLHEPDLDTGLVVPGRRAVVMPRPSKHIGLTYRMSKMMHEAMFTPGTPLSEWG
AATCAASADPMQGPRPLRVLEHLSKTALFACKDCGDCSLPEIAFLCPESQCAKNQRNGPC
GGTRDGRCEVDGYGDCIWLRAYERRKHDGEQDQLLPVTPVIQNQALRGTSSWANHWLGRD
HVARPALSDLPTRAHE
>A0A2H9PE67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeum sp. CG_4_10_14_0_8_um_filter_32_851|TrEMBL
MSLLRENFSRKFTATGEVSPPPCPDKTLFAREVEEMKPLMGRILGVNVVEGPGGRVLMSS
LGASIYMIQHGVEPILQQVVRDKNRVALQNDLISASIFEIENVLSIAGDHPACPASDNPK
SKPVYDMDSTTLIVMLKKLNEGKLWNGKDTNYENKNLNAKTNFFIGTGLSPTSSPLDGEI
YKVKRKLIAGCDFFQTQGVFDIEPIINFLNLYEKTIGEKISDKILVGIVPIWSYGMMKYL
LTLPGIVIGEKFRNDVNEARKKQKETGQKGLIEEIGVNLCVDLVDKIKGLGVKGVHIMPV
GNLHAMKEILDKSGL
>A0A7C7R9S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MKLRELFEEGRFVLTSEIGPPKGVLLDEMFAEIEPLKGKVDAINVTDNQSSVMRLGSLPV
CHILKERGFIPVFQITCRDRNRLALQSDILSAYVLGVENVLCITGDHNVLGDHPQSKPVF
DLDSVQLIKTVRGLTRGRDMVGNELEGSPEFCIGAVVNPGADPLEPQIIKMELKAEAGAE
FFQTQTVYDVGQFERFMSQVERLKRPVMAGIVFLKSAGMARFMNQNVAGVSVPDDIIKEL
ASVSKEDRPKKSVEITARIIRSLKDMCQGVHLMPLGWDRYVPDVLKEADLR
>A0A7G3CZ90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carideicomes alvinocaridis|TrEMBL
MTAAPRVSFEFFPPQNLEASFRLWDTVQHLSPLSPHFVSVTYGAGGTTRDLTRDAVKTLH
KASGLNVAAHLTCVSATREETLQIANEYADAGVSDIVALRGDPPKGSGAFKAHPEGFGSS
VELIEALADTGRFNIRVGAYPDPHPDCRADGGDVEYLKRKFDAGATEAITQFFFEAETFF
RFRDACEKAGIDAPIVPGVLPIENWKGVKRFAQNCGAHIPAWVEHAFDSAIRDGREDLLA
TAICTELCSDLMEGGVDKLHFYTLNKPELTRDVCHALGVVPKVSLRDVA
>A0A433EC24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HSID18067|TrEMBL
MTTVHPALSYELYPPRSHASCDSLLKTITELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLALRGDIPPENTRPLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAARLAGVQMPIIPGIMPVTSLTRLTKLCELAGFEVPRELAHRLETASDS
RELHRIGVEHALDQCRKVLDAGAPGLHFYTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>I4LJZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis 0288E|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIHSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKISEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A1A9MBK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas floridensis|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAAKLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VERLGVEVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGRKMQAYGDDADAVRAFGAEVV
ASLCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A5C7ACE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus aquimarinus|TrEMBL
MKITEHLGSAKDTLFSFEILPPLKGQSLKELLEGIAPLMDFKPPFVDVTYHREEYIYKKH
PNGLLEKISTKKRPGTVGICAAIMNRFHVDAVPHILCGGFTKEETENALIDLNFIGVENV
LALRGDAPKTEGKFIPETEGHGYASELVEQISKMNQGRYLHEETEIGFQTDFCVGVAGYP
EKHFEAPSMKFDLKYLKEKVDKGAEYIVTQMFFDNQKYFEFVDQVRAAGITVPIIPGIKP
ITTLGQITMLPRTFFLDLPDPLMDELEKCKTNAEVKEVGIEWSIQQCKELVKKKAPSLHF
YTMSKADTTYKIAKEIF
>A0A1U9RR99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carsonella ruddii|TrEMBL
MKNISFEIFPNKDIKESIKIVKNLEKKKPIFISITCNKNNNFEFVKNIKNKTNIKIIPHI
ICDNIYNIILKIINFIKIKIFNFIIITGDNIKNNSLYIIKKIRLLFGHIIKIFSGSYLEE
HKLTNNMNKEILFLYKKKKIGINLFLTQFFFNFNIINYYLNKIKKTYVNKNFVPGIFPKK
NIKEILLFINKCKIELPIWIIKNYNIINIKNYLLKNLNLFKHFHFYTFNKIEFINFYLK
>A0A5D0RR85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muriiphilus fusiformis|TrEMBL
MSTPRVSFEFFPPQNIEAAFRLSDTVRDLAPLDPSFVSVTYGAGGTTRELTHDAVATIHK
RYGLNVAAHLTCVDASREETLAIAETYAGIGVNEIVALRGDPPKGAKGFVPHPEGFADSV
ELIEALAATGKFNIRVGAYPDPHPEAADTDADVAWLKRKIDAGATSAITQFFFEPETFFR
FRDKCEKAGIDAPIIPGILPIENWAGVRKFATRCGAHVPGWLDDAFDKAARDGREDLLSV
ALATELCADLIEGGVKDLHFYTLNKPQLTRDVAHALGVTPKVTLQEVA
>A0A3Q2NNI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fundulus heteroclitus|TrEMBL
MVNQVQQVEGCWQSTKGESSGASNSSGESSKEGSRCSTPVLDADRSDRLQEKMRKRIASG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTRERITGYLAKAKHLGLKNIMALRGDPVGDDWEEEEGGFSYAI
DLVKHIRSEFDEYFDICVAGYPTGHPEAESYQQDLWHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIHQAVEMSRVLLDSGKVPGLHFYTLNREVATVEVLRQLGLWIEDPRRPLPWAVSANPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKET
LLQMWGEELKNEESVFEVFTCYIAAKPNRNGQKVMCLPWNDEPLAPETNFLKDELEKVNR
CGVLTINSQPNINGKPSTDPVVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGHNMTNAHELQPNAVTWGIFPGREIVQPTVVDPVSFMYWKVCYQDSMKE
>V8D4Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia sp. D3|TrEMBL
MSSQQSHPSIVQRLAEPHPGPVPFSVEFYPPRDEQAEARLWRTVRIFERMGPAFVSMTYG
AGGSTRDRTLRITGQLARETTLLPVAHLTAVGHSVAELRAMIGGYADKGITNILALRGDP
PGDPLGEWVKHPEGVEYAEQLVRLVQELGDFNVGVASFPEGHHRAPDLDHDTKYLVSKLR
AGAQYSITQMFFDVDDFLRLRDRVTAMDPEQGAKPLIPGIMPITSLASVRRMVELSGSVL
PEAVDRRLAAAAGDGSEENREAVRAVGIDLATEMAQRLIDEGVPCLHFCSLNFAKATSEV
LERLGMNVMAA
>A0A5B8JJ35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. UKPF54-2|TrEMBL
MPKAGSFSPATGPSSFADVSHRPCEAPSSGASHGEPAGSGSVRSGLSAPARCAGYSLEYP
VTVHSLTSISPSTQPAGNDSELPTRLEIVPTDGIVARVQAGLPAGSKLTVTCLPHHGVQS
TVQTAVELGRLGFAVVPHLAARSLESRAELAGILKDCEAAGITEVFAIGGDAAQAAGPYP
SSARLLEDIAELSGGRIAAGVAGYPEGHPKQSQLHMLDALLEKQHLASSVVTQMCFSAAR
IGWYVELLRREGVTLPVWAGVAGSVPRTKLVALASKIGVGPSLRFISRKGPLARRLLDGG
NYSPRRLVSELSPVRPALAGVHLYTFNNLEPYAAVRRAESAAAPAAMPPGRG
>A0A7X1P7M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTTPRTRTYSFEFFPPNTQEGREKLRMTTRQLAQLGPEFFSVTYGAGGSTRDRTLETVLD
IQASGHAAAPHVSCIASTRDSIRETLTRYRDSGIRHLVALRGDLPSGLATAGEFRYAYEL
VEFIRHEFGQQFVIEVAAYPEYHPQARNALEDLRNFKRKIDAGADSAITQYFFNPDCYFH
FVDECEAMGIDIPIVPGIMPINRFSQLARFSDACGAEIPRWIRNKLEAYGDDVDAVRAFG
LDVVTALCDRLLQQGAPGLHFYTLNQAGATTTIWQRLGL
>A0A3D8IFF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter ganmani|TrEMBL
MYQTSNHSLANSPFLSTQIESFIQRLTQQDKCFTYEFSAPASFDLEPLFDALHQAQFLNK
LDAFICTDSPLGKLKHSAILASFKLQNTFKIPSITTISMRDKNTLALQSDILGMNSLDLR
MILALTGDPLRLGNQPQAKGVFEGNSLLLLRIIEALNQQRDINGTALSGNSKPIYPFCVL
NSYANKKENLYRKMQEKIQNGAQAIFTQPIYDLNIAQELLEWCEKINAHNDTKCALVFGF
FPIFSYKTALFLHHKLPGVFVPMALLEEMQKANKQNTESQVGLEKSQTLFSNLYQLHQKF
HFMSANKPHLIAKIIC
>A0A7L2FNA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Quiscalus mexicanus|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRRVLQGGPLFIDVTWHPAGDPGSDKETSSMIIAYTAVNYC
GLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVK
HIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVYAGADFIITQLFFRPETFLKFM
KDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVE
LAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRRVE
DVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKM
WGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGIL
TINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVRALLKVLRRYELRVNYHI
VNVKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYE
EESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7V9RW51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MVLGLPSRMPGGAETVRDLIAAGGRSFSFEFFPPKDAEGERALWRALRELEMLDPTFVSV
TYGAGGSTRERTVAITERIAQDTTMTPLAHLTCVGHSRETLRSVIGSYAGAGVRNVLALR
GDPPAGPTATFEAHPEGLRYALELVELVKSLGDFCVGVAAFPEAHPSAESLEADARVLAA
KARAGADFAITQLFFRPEDYFRLVDRAAALGVDIPVIPGIMPITSLAQVTRMAELSGAEL
PREIVERVARFDGDPAAVRAEGIAVATELCDLLLAGGAPGLHFYTLNRSRATREIYAGLR
STVPVP
>A0A7X8K192|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MENRFKKSLLDKSTLSVTWELVPGRGAREPQQEFAIQAAEQAAKGGKVHALTITDNPGGN
PAILVDYLGIEVFGKGIEPLVHFTCKDKNRNQMESQLYALDRANVRNLLVMTGDYPTTGF
KGRPKPVFDLDPIHTLELIEEMNKGLEYPGMKGTIKHQPSDFFAGAAVSPFKATEAEQMV
QYYKLKKKLDAGAKFIITQVGYDIRKYHELLLMMKMLGYEDIPVVGNIYVLPFGAAKVMN
ANRIPGCVVTDKLVADIDKERSDEDKGVGARLLRAAKMYAWMKGMGFDGVHIGGHNVKYE
QVEYIIEKGEELSANWQDLIPEFQYPQPNGFYVFEQDEKTGLNKEQLTNRKNRPLDADTP
FVYSLSRFVHNMMFEPGKNFFGMMRNISAKIEGTPREKRFHRFEHMNKVRLYDCKDCGDC
ALMDLAYVCPMSQCPKNQRNGACEGSYNGWCEVYPNERKCVWVQAYARLKKYGEEEQLNS
YRVDPCNWDLYQTSSWINFYLGKDHSAKRLGIKNPKAKKED
>A0A6N7YJ90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum soehngenii|TrEMBL
MKNDGMDEMNIREYLENHKLLTDGAMGTYFDTVEKENYICSEEANITNPSLVRQIHKNYV
KKGAQLLRSNTFLANRETLLSLQQNRAEQFQNVSLKELVTKGYRLAEEVAREAYSESYPV
FPAADIGPILEEKESEETDILQQYYEICDSFLEAGANIFVLETFPDTEYVLKMAEYIRQI
CPEAFIIGQFSLTPTGYSRTGFHYKTILRDAVQSGLLDGAGLNCGIGAAHMKRFLEAYIE
EYGVPEDMILTALPNCGYPQIVRGHVIYSDSVTYFGEKIKEVSELGVRVLGGCCGTTPEY
IGEIYRTLFQAEHTLKVPTRIVWTDAAGRIQKRQEQLAHIKSAEGKNKTIKKEQVVNTFR
RKLEKGELVCAVELDPPFDANDTKLVNGAKALLSTKADIITIADSPLARSRADASLMAAK
IKMQTGMDVMPHLACRDKNRIAIRSGLLGSYVNEIRNYLFVTGDPVAREDREFTKSVFDF
NSIRLMKFAQSMNQEIFADDMIFYGGALNQNGASPENIAGRMIKKIEAGCSYFLTQPVYD
EEGIKRLAFLKERTGAKILIGIMPLVSRRNALFIKNEMPGIYVPDRVVEKYKENASREEY
EEAAVEISKKIIEMGKEVGAGFYFMTPFNRVSLVKSILEYV
>A0A1M6GX10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus lacus DSM 15449|TrEMBL
MENKFKESLLDKNTLSVTWELVPGRGANEKAQLTAIASAEQAAKGGRVHALTITDNPGGN
PAILADYLGMEILKLGIEPLVHFTCKDKNRNQMESQLYALDRAKVRNLLVMTGDYTYSGF
KGRPKPVFDLDPSNTLQLIADMNKGLEVPGMKGPTYHAPSDFFAGAAVSPFKSTEAELMV
QYYKLKKKIQGGAQFVVTQLGYDARKCHEVIQFLKVNNLDIPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNEEKSAADKGVGQRMLRAAKLYAILKGIGCAGVHIGGHNLKYEQ
LEYILDKGEELYPNWQDLVKEFDYPQTNGFYYFEKDEKTGLNTDRPTNRANRPLDAPAGA
MNSLMRGMHSLMFTPNKMLFPVMRSMYHAAEGKKKAEKRLHALEHIAKVVMLDCKDCGDC
AILDIGYLCPMSQCPKNQRNGACGGSLDGWCEVFPKEKKCVWVRAYARLKKYGEESTLDV
PPVPPANWDFYQTSSWSNFYLGKDHSAPLLGIKPPESKIKK
>B9WDQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841)|TrEMBL
MKISEKLSQAHRGSKPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALEKAYKSGCQNILALRGDPPLD
GSESTGDFKYAKDLIKYIHKKYGNHFNIGVAGYPEGHPEEEDEQKTLQYLKEKCDAGADF
IITQMFYDVENFVSWCSKLRKIGVDIPIIPGIMPISTYAAFIRRAKWSEIVIPQHFLDAL
DPIKDDDFLVRERGTELVSEMCNKLLQSGYVNHLHFYTMNLEKATVMILEKLNLIEAIKS
HDVVGGSELPWRKSLHPERSKESIRPIFWQHRKYSYISRTATWDEFPNGRWGDSRSPAFG
DIDLCASELLRQSPKKAFELWGLPQSLADLSGIIINYLKGDLKSLPWSDGPVGDDTRVIV
DDLIYLNQHGFFTMNSQPALNAVKSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDQ
VEEFNIKGAESSSAFISYYAVDKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSF
LAWKDEVYRLFTEWAKIASSNLVEADQTQVNEFVRLMKKFGDEFVLCNLVNNDFVDGNST
LFDLIKRLNVNDLN
>A0A2K6DSM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macaca nemestrina|TrEMBL
MVNEARGNDSLNPCLEGSASSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDLCVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYE
EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDALELLNRPTQNEREMEAP
>A0A537AI18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MSPMSYPASATEPRLDPRISELVAAGSVEISPRELHRAKDVGTLLPAGSCVYIPSLPGLP
LARTLEAIAAIRDAGLDPVPHVSARRILNRDEFRTFLRRASSEYGVHRVLLLGGDEPRPK
GPFVDSLQILEEGLLADCGVREIGVAGYPEGHPRISLNALEKALARKLELAAAQSIGVYV
LTQFSFAPARVVDYCATLARLWPSLPVYVGIAGPADPAALLRYAQRCGVSASLRALRSLG
SGIAKLVTNTDPRDQLVALARYTRNREPSNVVGVHLYSFGGAVRTAAWMSDHL
>A0A1Q4B243|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micrococcales bacterium 73-15|TrEMBL
MTTSELYRPPRPTISYELYPPRTPKGEAQVWETITRLAEGDADYFSVTYGASGSTAERSQ
ALVARILAETTVPVIAHLTCVGRSRAELRAVVEAFLDAGVRDFLALRGDAPQGETEWTPA
PDGFSRASDLVELIREVEAERFGARASSGLARLVAHRGQHPRVSIAVAAYPGYETTAAVA
AGDDPAVGGAEAGAVGAAPATRRYACRPDELAALRAKQDAGADFAITQLFFDAEAYRELQ
QAAREAGVTIPLVPGILPLTDPARVRKLCALNDIPEPTALLTELDAAATRDEATRIGLRA
TARLAREVLEAGAPGLHLYTFNQHGGVSALLDEVLAPA
>A0A5B3GW03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes onderdonkii|TrEMBL
MNVVDIINKAVEQRRTRFAFELLPPLKGDGMGGVFESIDRLIGFDPAYINVTFHREGIKQ
AVRPDGSVEWHVVRRRPGTVGISAAIQKKYGVEVVPHLICGGQSKYDIEDALIDLDFLGL
HNVLALRGDKSQNEKFFMPHPQGHTHAVDLVRQIAAMNRGQFVDGEVEECHHSKFSIGVA
GYPEMHEEAASPEADIACLKAKVDAGAEYVVTQLFYDNARFFDYVRRCREAGITVPIIPG
IKPLSTVRHLTLLPRTFGCHIPEELEREVLRHKDDPKAVREVGTEWAVAQSRELVEAGVP
VLHYYPMGKADNIIKIAKAIF
>A0A0G3WL35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endomicrobium proavitum|TrEMBL
MSFKQKLKSNKFLITAELFPPKGTDVSLFLKRAACLKDLDAVNVTDNQRASMRAGSLAMC
KLLLEMGIEPVMQLAARDKNRIALQSELLSANVLGIENVLLLSGDHPSAGEYIGTKTVYD
LDTIQLIKTARLLETGVDLAGKKLSGAAHFCVGAVVNPSAEPAELQALMFEKKIKAGAEF
FQTQTIFDASQFKKFLCKIKHDGVKVLPGITLIKSVKFMQFLQKLPGVNIPQNVQDRINA
AKDPLAEGIKICAEIIRELRGFADGVHIMAIGAEDKIPEIIKNSL
>A0A372JWI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. DHOC27|TrEMBL
MNPLELSFEFFPPKTPDGVEKLRATRAQLAALKPKFVSVTFGAGGSTQQGTLDTVVDMAK
DGLEAAPHLSCIGSSKDSLRAILNEYRAHGIRHIVALRGDLPSGMGSVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESYGDDRESIRAFGLDV
VADLCQRLVDARVAGLHFYTLNNAAATQAICERLGA
>A0A542ERZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella jejuensis|TrEMBL
MSGFELICEVEPPTRPDLKKVRHQIGVLSAVADGFLIPDNHIGRATVSSVAVANEVQLMG
ARGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDDPAEGARTSQLTVRRMIEQTRE
TTYPGCNPFKVGAATRLRPVPRWKAEADFLYVQVSYDLDELLRWRESVRLDIPVYAGVMV
LASTQMARNLAGLSQLKIPDALVEVVDKDRDAGVDHACDQILKIRDSGAFEGVHLIPVSR
YRQVAAKLEREL
>M6W8D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira borgpetersenii serovar Pomona str. 200901868|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTQDGDLKLMGTMKELARLDPDFVTVTYGAGGSTRDK
TAQILSEISKNYSFPTVSHFTCVGANQDQIFKTLKEIRSSGIVNLMALRGDPPKGEGKFK
KMEGGFENATELISFIRSEKLDFCIGGGCYPEKHPNAKSLEEDVRNLKRKVDAGTDFLVS
QLFFVNSIFENFLNLVRKADIRVPVIPGIMPITSFSQIERFRSIAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSIKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A8D9L4A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus eutactus|TrEMBL
MNILESLKDKLLVADGAFGTCYVGMYGEQGTVAPELANMRHPERVLEIHKEYVKAGAGLI
RTNTFAANTASLDADMDYVISNVRAAVKLAKQAADGEAGTDHKKVYIAGDIGPIPADAGL
TLNERVSQYKLLGEAMQDMGVDIIWFETFPEFNVLEPVVKHLKERKNTPVMVSFCVNQFG
YSNCGFSARALLSQVAGNQDVDCVGFNCGVGPYHMLQLLKKLDIDCGKPVSVMPNAGYPK
FTQSRLVFNDNKEGFIDKIQDIAALGADIIGGCCGTNPEYIHQIMERVKTGDIAKAAKVH
VEKVQADSAVKDNFLKGRLERGGAATKNADGHKHKLIAVELAPPVDVNDQKLLDAAHILK
QSHVDVVTFPDSPSGRTRADSILMAEKVHKETGLRVMPHLCCRDKNAIAIRGSVLGAQLN
GIKDFLVITGDPVPVMFRQTTRSVFNFDSVGMMKLLQSMNEEVFSGDKITYGGAINQNRL
NTKFEIDRIKRKMEAGAEFFLTQPVFSREQAQILRDMKAETGATILVGIMPLVSRRNALF
MKNEMAGIEIPDEIIERYSGNATRQEGEECGIQIARDILEYTSDFADGYYFSFPFNRVHM
LAHIVD
>A0A829TIL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei NRIC 1981|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A674MXG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Takifugu rubripes|TrEMBL
MVNQVQSVDSSWQSSKADSSGASNSSGESSKESSRCSTPVLDADRSDRLRDKMRRRIESG
DHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKDKITGYLGKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAV
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYQQDLRHLKEKVDAGADFVITQLFFRAETF
LKFLDDCRTIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITSILEPIKDNDAAIRN
YGIQLAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWTEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELLSEESVFEVFTFYITAQSNRCGQKVLCLPWNDEPLAQETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWA
KLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDSPAAPPCEDATP
>A0A2X2LVI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MGLEISNKRISAYKLFFIILKSNRHLDEEGVDALLFETYYDLEELTNVISRTRKKYDIPI
IAQLTASNTNYLVNGQAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLS
CYPNASLLDIENSEFKYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTL
KPVNDKK
>A0A7X1B8M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagicoccus albus|TrEMBL
MSQTPISQLFSQERPLLSVEFFPPKSDDALEKLIESADDLAFYQPDFVSVTYGAGGSTRD
RSAKACELLRDEHEFNIMPHLTCVGASRDELAVTVNGLYESGYRNIMALRGDPPKDSPSF
VVAENGFAYASDLVAFIKELHPDISIGVAGYPEKHPEAADLSTDLRNLKTKVDAGASFIT
TQLFFDNSDLYRFLEEADKLDISVPVIPGLMPVLSLKQVKRITSMCGASLPAELEKHLNL
AGDNDELVRQIGIRWATEQLQDLIEQGLPGVHLYALNRSDVATELMSAFRSSVE
>A0A380EEJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPGIKMSDEILQ
QFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAAYSKSITAHK
EAIL
>A0A291MUN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium yanoikuyae|TrEMBL
MTQTDRARHDAEGPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFVSVTY
GAGGSTRERTHNTVARIAKETPLAAAAHLTCVAASKAEIDEVADAYWEAGVRHIVALRGD
PPEAGTGFQPHPDGYKGAAELVEGLRKRHDFEISVAAYPETHPDALSAQSDIDNLKRKID
AGATRAITQFFFEADTFFRFRDTVAAAGIDADVIPGIMPVSNFAAVQRMSAMCNTDVPAW
MGRLFDGLDQHPAARQLVSATLAAELCRNLYMGGVRDFHFYTLNRAELSYAICHLLGLRP
QVAVDA
>A0A3E4N3L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola plebeius|TrEMBL
MKVIDLIKNSKEPVFSFEILPPLKGNSIQKVYHIIDKLREFDPKYINITSHHSEIVYLPQ
PDGNLKKTTVRKRPGTVAIAAAIQNKYGIQAVPHIICKGFTKEETEYALLDLNFLGINNL
LLLRGDSKPLDIAEKDLCLYHEHATDLQEQVNRFNQGFGLDGSKIEGIETPFSYGMACYP
EKHEEAPNMESDLFYLKEKVRNGADYVVTQMFFDNEKYYAFVERCRQEGIDVPIIPGIKP
VVFKNQLNVLPKVFRTDIPEAFASELRKCTTDEEVKAVGVEWCKAQCKDLLAHGVPGLHF
YTFMASDSVYKVAKEVY
>A0A3L7ZSI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides distasonis|TrEMBL
MKVIDLIRNSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDTKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIHYLKEKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRTDIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A430C909|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium yanoikuyae|TrEMBL
MTQTDRARHDAEGPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFVSVTY
GAGGSTRERTHNTVARIAKETPLAAAAHLTCVAASKAEIDEVADAYWEAGVRHIVALRGD
PPEAGTAFQPHPDGYKGAAELVEGLRKRHDFEISVAAYPETHPDALSAQSDIDNLKRKID
AGATRAITQFFFEADTFFRFRDTVAAAGIDADVIPGIMPVSNFAAVQRMSAMCNTDVPAW
MGRLFDGLDQHPAARQLVSATLAAELCRNLYMGGVRDFHFYTLNRAELSYAICHLLGLRP
QVAAELMA
>A0A5C6KC23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides distasonis|TrEMBL
MKVIDLIRHSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>S6H8K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Osedax symbiont Rs1|TrEMBL
MRANLATRLADPTRGVYFVGTTPPRAEVAEQDMLVIADKLLDRLTSVDYDGLVVYDIQDE
SSRNSAPRPFPFKATYDSRIYSNVLSEKSNHPTITYKSVSAKSKTEFNQWLDEAWTEYGI
RNIVLVGSPSSDGQVVLPLKEAYQSLAAHRQDFNLGGVAIAERHHKKGDEHLRMQQKSID
GCKFFITQAVYNADATIDLLQQYAALCKQQGCKANRVILTFSPCGSEKTLDFMNWLGIST
PSAIKTRILDADDSLAESITICEENLQKIINYCLNLEIPLGLNIESLTNRKEEIDASIKL
FKLLKATLDLNLAKNF
>A0A0L8RJ81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces eubayanus|TrEMBL
MKITEKLEQHRQSSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPVSMIDDALENAYHSGCQNILALRGDPPRD
AQNWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPSKDSQLDLAYLKQKID
AGGDFIITQMFYDVDNFIAWCAQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQVSIPQS
FLAELEPIKDDDELVRDIGTNLIVQMCQKLLHSGYVSHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANRCLELWATPTSIHDVACLVISYLNGNLKCLPWSDVPIN
DEVNPILSHLVELNQHSIITINSQPQVNGIRSNDNVHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIETLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILDEWKLNMDNNDKPQSSRFIQSLIDDYCLVNIVDNDYISPEDQIHSILLAL
>A0A2V5M432|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
EGRVVEFNHAAAQLAKESAAGKDVCVAGSVGPLGISALEAEERGVDRGRCFYEQIQALLE
GGVDLIFLETFMDDAEMQIALDAKNSLSDCATICSFACEPEGRLGSGVSILEAFSKLRAG
GVQITGVNCMNGPHATVQLLQRIPIDGLLAAYPNAGYPKYTDGRFIYHAAPDYFAQAARE
MVAEGARLIGGCCGTNPRTIAAISRAVAELKPVRSKGIRVAAVAPAPAKKVVTTPEESLL
DKIAAGKRVIICELDPPKTLALEKYFRGAQELVSAGCDAITLADNSLAILRVSNLAIGAM
LKERFGITPLLHLSCRDKNVLGLQSELLGMAALGMRHVLPLTGDPARVGDHPGASSVYDV
NSIELISIIAKLNDGFSHAGKSLKARTQFVIGCTFNPNAKNLDSQINRLERKVAAGARFA
MTQPVFDVTLVEETKRRTAHLNIPIFIGIWPLMSARQAEFLHHEVPGIIVPDKIRKRIAD
VPLEKATEIGMEIAREIVSSAGAEFPGIYLITPFLHFDSTCELARFARKM
>A0A7L7KWY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus pabuli|TrEMBL
MTETNPTLSFEVFPPNSQVGVDNLTDTLDQLKGLNPSFISVTASNHKLNYEETTINLAKY
VKDNLHCHTMVHMPAAYVTKTEVRSILNRLEKMNIHQVLALRGDIVEGYVPEKDFKYASD
LTQFIKQEKPDFTVSGACYPEVHPDSKNRIDDIKHLKNKVDSGCDQLITQLFYDNEQFYR
FQEECAIADINVPILAGIMPIVNRKQALHVIENCAARLPKKFINILDKYKDNPVSLKEAG
IAYAVDQIVDLVTNDVSGVHLYTMNKADTAKHIFKNTASLFHLDGVAE
>A0A3N6J8V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ADI98-12|TrEMBL
MALGTASTRTDHAPTVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSEDWDTDIRYFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LQDDKG
>A0A2V5WAK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIIDIMRGNSPTFSFEFFPPKTPEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIEAILLRYAKSAIGNILALGGDSPAGIAYDKSR
DSFQHAIDLVKFIRRFNESGAHPDHRGFGIGVAGFPEGHPATPNRLVEMDHFKAKVDAGA
EYIVTQLFFDNRDFLDFRERCALNEIQIPIIAGIMPITSISGFKRIAELAGGARFPAKLL
RALQRCQNDPETVKRVGVQYALEQCRDLLDNDVAGIHFYTLNRSDATRVIFDSLAFPRHR
NAQASSA
>A0A401KKI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus awamori|TrEMBL
MGSAVRHGAFSGGSIGRRKSCSSPPPSFTPSFLAFHSLSSVRHRVAVSAAAETGLIMEKI
TDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGSTAARS
LELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMH
GEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDGQDPARDLPYLIEKT
QAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTKLSHV
KIPPHVLSKLEEVKHDDDAVKRIGVDIITDLVHGIRDLVSPGLRGFHFYTLNLEKTVSFI
LERCELIPPYTEIDDSDALADGGNLSALDSSSYIAPNGAPIRTLASRRSSVSSIPHNRVI
VDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWSEGGA
EEDSNGLNAETAIIQPELLTLIDKKGWWTLASQPAINGVRSDDPVFGWGPPGEGFVFQKP
FVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNAKGDFESSLPGPNTDDPDPIDINPANV
NAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDDTKNDVW
LVCVVGQEFGAGTEPGSEEEEDEKKWMWRELANSQ
>A0A2V5Y5K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
DYIVTQLFFDNRDFLDFRERCVLNEIHIPIIAGIMPITSISGLRRIAELAGGARFPAKLL
RALQHCQNDPEMVRRVGIQYALEQCRDLLDNNVAGIHFYTLNRSDATRVIVDRLGIPRRQ
NAQTASV
>A0A1H9G5R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. yr375|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFYAPKTPKGERGLWDALRRVEAVAPDFVSV
TYGAGGSTRATTVKETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGPWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDTDVTHFVD
KCRAGADYAITQMFFDPESYLRLRDRVAAAGCVTPVIPEVLPVTSVRMLERLPTLSNAHF
PDALKERILTAKEDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A2V5KHR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
VTQLFFDNRDFLDFRERCALANIHIPIIAGIMPITSIGGLKRMAELAAGARFPAKLLRAL
ERCQSAPKMVRRVGIQHALEQCDDLLHNDVAGIHFYTLNRSDATRLIFDSLGIPRHRSAQ
ASSV
>U9VN16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. Heron Island J|TrEMBL
MAISNGSHSASSLLRSAIAERQFIITAEVMPPKGGDPSHMITMAQQLKGRVHAVNITDGS
RAVLRMSSLASAVLLKQVGIEPICQLACRDRNSIALQADLMGANALGIHNVLALTGDPVK
AGDHPKARSVFDLESVRLLRTIGLLNQGIDLNEKKLPDGALDIFAGAAVDPQCPSWSGLQ
KRFERKVNAGAQFFQSQLISDFDRLEKFMDQIAAPTEKPVLAGIFLLKSAKNAAFLNRNV
PGVHIPDDIIERLAAAEDPLQEGIIIAAEQIKLAQTLCQGVHIMAIRREDLIPEILDRAG
IAPVCSEPAATDVSSQTVSSQQDLAVV
>A0A2V5JRL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRGDSPMFSFEFFPPKTMEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQRTTKLDPIPHLTCVCHNEEEIEGILLRYAKSAIGNILALGGDRPIGIAYDKSR
DSFQHAIDLVRFIRRFNESGAHPDRRGFGVGIAGFPEGHPATPNRLLEMDYFKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALANIHIPIIAGIMPITSIGGLKRMAELAAGARFPAKLL
RALERCQSAPKMVRRVGIQHALEQCDDLLHNDVAGIHFYTLNRSDATRLIFDSLGIPRHR
SAQASSV
>A0A1X1GX77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLQTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2V6GIX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMQGDSPTFSFEFFPPKTPVAAEILYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQTTTKLDPIPHLTCVCHKKDEIESILIRYAKTCIGNILALGGDPPRGCSYDKSG
DAFQHAIDLVKFIRRFNESGGHPDRRGFGIGVAGFPEGHPATPNRLVEMDRLKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALAEIHIPIIAGIMPITSMSGFKRIAELAGGTRFPAKLL
RALQRCENDPEMVSRVGVQFALEQCHDLLDNNVAGIHFYTLNRSDATRIIFDTLGIPRRR
NAQAPTV
>B0VUU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain SDF)|TrEMBL
MTKRTPISFEFFPPKTDASAEKLRIVHQELQHLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A2V6AWW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMQGDSPTFSFEFFPPKTPEAAEILYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCICHNEEEVEAILLRYARSAIGNILALGGDRPRDIPYDKAR
DSFQHAVDLVKFIRRFNESRTHPDRRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYMVTQLFFDNRDFLDFRERCALAGIHIPIISGIMPITSMSGLKRIAELAGGARFPAKLV
RALQRCENDPEGVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRVIFDSLGIPRRQ
SAQAPTVSSSHKGRKRLAN
>A0A4Q9AWB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus thermamylovorans|TrEMBL
MKIRDLLRERRGPLFSFEFFPPKTPEGEEALFRTLGELKAFRPAFVSITYGAMGSTRERS
VLWARRIRDLGLRPLAHLTVAGQSREEVGEVLERFVAAGVENLLALRGDPPPGERVFRPH
PEGFRYAVELVARIRERYGEGVSVGGAAYPEGHPESPSLEADLRHFRAKVEAGLDFAITQ
LFFNNAHYFGFLERARRIGIGIPILPGIMPVTGYAQLRRFTEVCGASIPGPLLSQLERHQ
EDPKATLEIGVEHAARQVAELLEAGVEGVHFYTLNRSPATRMVLERLGFRPRAEQAEGES
PGGP
>A0A2V5JK02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIIQGSSPTFSFEFFPPKTPEAADILYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEQEIEEILLRYAKAAIGNILALGGDRPVGIAYDRSR
DSFQHAIDLVRFVRRFNESGAHPDRRGFGVGIAGFPEGHPATPNRLLEMDYFKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALANIHIPIIAGIM
>A0A1E5R2S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hanseniaspora opuntiae|TrEMBL
MSNISNSYLKKLSTNGAKPSISLEFFPPKTKMGLDNLIKRIERLTIAVQPIFITITYSQL
NNKKTLDLLEMIIKNNSDVFKNVNICCHLTCTNSSYQIINETLDKCLELGIKNILALRGD
PVETDVNNNTDFRYAVDLVRYIKKRHGDDFCIGVAAYPEGHYNNEYNPNTNNYTSSQSFR
EDLVYLKEKLQAGASFIITQLFYNVEKFLQFYNEYKLMIPDYKKYLMIPGIMPINNFMIF
NRATKLAHVDIPKHIIDRFPLDIRNDDDQVRNIGVNIMVEIIERIYEKTNHEVNVFHFYT
LNLEKSIAQIISKSTLLSQILEDSESDESESSYEDXVYSSDDEVDEGGESSTKTLXSXVQ
TSDNNSTNKPLHTSEDIKLALRKDSDMEEDEDIIFDSDSDEQQDEPVNIKTFKELSIDPN
SDKEIAPSSEHYSTKVQQYNKKLINPPKRKRTRSSQSSITSGLLSSLNKSLKRKPIKQHK
KLFREISKGTNPQLGKTILWDEFTNGRFGDSRSPAFGEMDGYGPTLKVASHKAIEYWGNP
TNIXHLIEVFEQYLLNSIPVLPWCDLVGITPETGLIQEQLLELINDKQMLTTSSQPSCNG
ISSDDKIFGWGPSNGKVYQKAFVEFFISKEKWKSLRERLDKNEKFGYYCGNTRHFETSXK
NNNDSGSSCVVTWGVFPNSEVQQTTILEEESFKAWVEEAFQLWKEWAKIFPKNSSSQNFI
NQCYDDLLLVEVVYHDYSDFDGLWDFLLEDDGXEVDMD
>B2WMV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenophora tritici-repentis (strain Pt-1C-BFP)|TrEMBL
MHISKKLTQAREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQTVYGLETCMHLTCTDMEKSKLDDALREAYQSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGGTF
IVTQMFYDVDIFLEWVRKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTRCNIPQHWTDAL
EPVKNDDVEVREVGKMLVADMCRKLIAAGITHLHFYTMNLAQATRMVLEELDLLPDVEAP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNVKLWGSPMCIRDLSDLFVRYMEGKLDSLPWSEQAITTEAGPIRSDLID
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEYISEIITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDIVDTWYLLNIVHNDFHETRGIFPIFDGLEVKDMDKPLHNPSVDL
PGVNGTESTNGTNGTNGDAEAPGLIETAKAAAVEVTNGIKSLAVSN
>A0A090ZH89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus macerans|TrEMBL
MKPDLREALKNEVIVGDGAMGTYLYHLGFPVGISYEEFNLLRPDVIGDVHRRYVGAGARL
IETNTFSANYYKLSKFGLEAKVEEINRAAVRIAREAAGDVAYVAGAVGSIRGGKRANVTA
QELGDYYEQQIAALLTEGVDALLFETFYDLREIRIALGKARLLTDLPVICQFAVDQVGRT
LDGYAMQEAFGALLREGADVLGFNCHSGPKGIMSVMAEMNGPLDVPMSVFPNAGLADYVD
GEYVYGATPEYFGENAASFADLGARLIGGCCGTTPEHTAATAKALLGYAAPPLADERKLA
AASSSVVLNEAAAPETESGAAESGLYGRPNRPSLVDLAKERHTVIVELDPPRDLDIGKFM
EGAAALQAAGVDALTLADNSLAVTRMSNMALGHLVQSELGLRPLIHIACRDRNLIGTQSH
MMGFDALGIDHVLAVTGDPARFGDLPGASSVYDLTSFEIIRMIKQLNAGISFSGKPLKQK
AKFVVGAAFNPNVKHLHKAVERLEKKIASGADYIMTQPVYDPKLIAAVKAATAHLDVPIF
IGIMPLASGKNAAYLHNEVPGIQLPEEVLKRMEGLQGPEGRRAGVEIAKELLDTAMEHFN
GIYLMTPFMFYEMNVALVNYVREKSKQGASHLSRST
>A0A1I6ILG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halogeometricum rufum|TrEMBL
MSLSTRTVSHPEGVETLLTDARFELMPFESFDDEITQLPDGATIAITTSPQLGIERTVER
TEEARARGYEVVPHIAARYVEDRDHLADIADRLHDAGVTDIFVPGGDREEPAGEFESAYD
LLSALDEMGRSFEDVGITGYPEGHDFLDDETLWESMERKEPYATYIVTQLCYDPETVVEW
IEDVRARGVELPVEVGIPGVMKYQKLLKISQKVGVGDSIKFLKKTTGILGFVRQLVGSRG
TYKPDDLVDGLAPYVGDDAYRIRGLHIYTFNQTSDTESWRYGRLDD
>A0A6G6WB59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides anomalus|TrEMBL
MTERRGPSIRELLDRGDRSFSFEFFPPKDEAGEEQLWQAISALEPFEPSFVSVTYGAGGG
TRDKTIGITGRIAQETSMTPVAHLTCVGHTRAELEAILDAYAEQGIQHVMALRGDPEEGP
RSEWVPTEGGLTYALELVELARSRGDFRIGVAAFPEGHPSAASRDADADVLVAKARAGAE
FAVTQMFFRADDYFDLVERVRSRGVTIPILPGIMPILNLGAVRRQGELIGTDVPENVVRR
IAAHEGDTAAMRAEGIALAAELCETLLDGGAPGLHFYTLNRSKATLEIFHALNVTV
>A0A5E4KXH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon|TrEMBL
MSFREKLDSGKFIITAELSPPKGTDFKSMLEDAELIKDIVDAINVTDNQRAVMRMSPLAA
CSLLQNKGYETIMHLTCRDRNRLALQSELLGAYALGIRNILVMSGDHPVKGDHEGAKPVY
DLDSVQLLGLIQELNRGFDLSGNRLEGHPDFCTGAVTNTELNEVSLIKLGKKIRMGASFI
QTQAVFDADLFSSFVEKINQIKSKRIKILAGIIPLKSEKNALFLNKNIAGTKVPENLIDR
MRKAKNPEALGIEIAVELINELHGICDGVHIMPVGNHGSTRKILEKAGIL
>A0A7D4CPV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenuifilum thalassicum|TrEMBL
MKVIDILNNSKKTLFSFELLPPLKGHNIETIFSTIDKLKPYNPAYINITYHREEVVYTTN
SNGVKIPVKLRRRPGTVGLSAAIQQKYGIDVVPHIICGGFDAHETEDALIDLDFLGINNI
LAVRGDADKITGRFEAKPGGHSYAIDLVKQVANLNKGIYLEKLMEEPKPTNFCIGVAGYP
EKHPESPNCDSDIHYLKKKVEAGASYIVTQMFFDNRHYFRFVKRCREAGIKVPIIPGLKP
ISVKHHLNILPKVFDVHIPQELVLEVEKCKTNAEVTQLGVEWAIAQSKELVKANVPALHF
YTMGKADNIAQIAKNVF
>A0A1G2XVA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium GWF2_41_51|TrEMBL
MQTTGKKRLSQALTKREGFVIVAELVGGPNFSFAPIQKFLTAFSTNGGKDIPEGFNFVGI
TNPQSPGGVANIEPSDVNRFLVSKNLLGNLDFIPHISCKDMNADALTSLLAAHRSAGVES
VLALTGDKPVSAKGVFELESVGLIEKINRINNEAYLSAKAENLAATKQFFAGAAVSPFKY
NEESQMQQYFKMEKKIARGAKFLITQVGWDWKKSVELVRYLKENNIDVPVLGNVYLLSTI
TPAPRLMHDIKLPGCFVSDDLLAKVYSETLDEHIERAAQQVAMYKSIGAAGVDVGGVHDY
EMFIKILKRAAEIGDGWQQFKDNLCWPARRPFYLYDEAGTKARLSDYPKTNGHRFFNFMH
WAILDPDHKGFHWFKKTMKFFGADKGKGFVYKSFFMLEKPMKYCLFDCEECGDCYLPENF
SLCTIGGCEKGMDNAPCGDSTAEGKCGNNLDRICIGDRIYKAAGAEQGGLEKLRRTINKP
RIPALEHSASIPNYLFGRDHTMKNAIINIGEAIHASIPKTGQVMKQLLELGDDCFSKDSP
ELQYVIALVESQAADGADYIAVNIDQFGETDPTLAVKLMKEYVKLVRKFGRGVPVCVDSS
DDNVLIAGLKEWYDTNDKVQPPLINSIKIYTIDNMMPLKKHYDYKFIGLLINEAKEATDS
VDDLYNLAKKIYDAAIKHGFKAEEIFFDSTVFPLAIDMPMMPGVPGYTYRTFNTIKRIKT
DPLLKDCHFSLGVTNSVRDLPARKIGVTRAYVEVAMRYGLDAGIVNASHHLGSVPADPDL
VKLVEAYANLDGSNENLNVAMQLMGEFCSKNRKPSA
>A0A444S8R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium dahliae|TrEMBL
MDEFVDWDKAGDNVGMLLDHTGPLPPSPLEHILNNIADQDIDLMLANVDDDDFSFWALQH
FSEAGQEGQDAPLGSAPAASASASAFPMDFSAGPAPEPYQLPNPLPDFFWYKPAVPCTSC
SRSGLECKRIREGEYKGFCTSCVALWCPCSFAPSVPANNWSNDLSEDPVVTNDRDIPSSQ
GLLKASLSSAPLEMAPPSTVPPVQENTAAAAAAGAAVPNKNSPPPKIGARFSRESVKILK
TWLSGHNRHPYPSDEEKEMLQRQTGLNKTQITNWLANARRRGKIQPPRSTSPATHTLYAG
AVDIPRRPGTPAFDKSIANKNPLERWVDSPPDNEPASVTAIARAVASNSEMSSGLNSPHS
FAFTDDGSGRSLVDYSSTSSVGTSSGGSFASAYSHASRGSFGSFSSMQIRGRRRRRRRAA
PQRGPDDKTNLAAPFKTFQCTFCTETFRTKHDWQRHEKSLHLSLERWVCAPKGPRALNPA
TNQVSCVYCGEVDPDNEHIESHNHTTCQERSIEERTFYRKDHLNQHLRLVHNVKFMDWCM
KTWKVATPEIRSRCGFCGIIMDNWSIRVDHLAEHFKTGNTMADWKGDWGFDAPVLDMVEN
SIPPYLIDHERNTPFPYVAGGSPPESPRSAYELIKMELAFFMMNHEDKTGALPNDDEMLL
EACRIIFASEVLSLQGIDSNFSWLRDLFMSSPEVARQAQFGPLRSAIENRLSILKINGKD
NLFEACPLEKQLRDFVSNRTLLGLTPIDDELQVEACCIVGRIEEASTTPSDFIANWLVRF
INSSTGWLANFRQRAHLPRTEDIKNAYFRSTDMTKIDSTIHIYSRLETSLSEYMEDQRVL
GIEPTDEDLQRRARIIIYDFDDGWNQTAADSLVWLNAFRERHPPGGSFSQTQDSLVPNAS
EPAQTVLGLQQQLASSPPRSKHMGGATCMNDSNRFRRLARELRRFVTQTTSPNNPNQHVP
SDQELQHQARWIMYDDDDPWNQTPADNAEWLQRFKRDAGLLAAASPLEPNQDVVPSRTMA
EAAASSCPFNPKIDFSTPFSTGTTLAGTSPSSTGQGTRDQAVADAFFATFDTRHARPGTI
FCARELEDSLVGFVHSEAAAGRDFPRDEALRAKAREVMGAVRTAADDETLLGKFKAWVVA
EIAGEAQSSNATYNRPKTRQRVQKAPPVLDVPDIDEDAAERKRVLNVLAQRRYRERKREA
RTKSKDTKQQDDLSAVDGIQPPASSSHPDGSLSSVSPPDAPRTSVSPNDLLLTSGLDLGL
DMPWNAVSLEPTSVSTLAETFPCASFETIMWDSLSTPSSSSPPGSSSSLSSNLIANSTAM
SSINRSHLGTPAAPSPGEPFAPPVPVDDFTDRYLLPMADLTLLRAFLSIADRLGCATELW
SPTSNSPFNKGGGTPAALLPPNFRPTPTQRQLPHHPMLDFLPWPSVRDRIISIFNMPEAL
RPPGARDALAPIQFAYDLEDEAEGVRIWGGDPYDATGWEIGQTFFERWWFIFDRDVVAQS
NRLREIRGAARLHLRGPRVEELGGLPTFWNGLLPFPPLLYLEMLADAERDGQPSFSFEYF
PPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIAELTCEMVTQAQSVYGLETCMHLT
CTDMGLDKVNDALRKAYKAGCTNILALRGDPPREKEKWVAADGGFEYARDLVKHIRATYH
DHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGATFIVTQMFYDADNFVRWVGKVRERG
ITIPIVPGIMPIATYASFMRRAKHMNCSVPQEFMDALEPVKNDDNAVREVGKVLVAGMCR
KILAAGIHHLHFYTMNLAQATRMVLEELNWMPTSERPLKQALPWKQSLGLGRREEDVRPI
FWKGRNKSYILRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEQNIKKWGEPQTVQ
DIATLFVRYLRNEIDCLPWSESPLTNEADPIREDLIALNKRGIITINSQPAVNGVKSSHA
VHGWGPKNGYVYQKSYLEMLVHPDLYPEIISRIEKHPDMTYYAVTKSGNLKYNAPSDGPN
AVTWGVFPGKEIVQPTIVEGISFVAWKDEAFRLGLDWAHCFEQSSPSRVLVERIMNEWYL
VNVVNNDFHQQREIFDLFEGLSVKEYDDIKPVAKDVAPDAVSAPTNGTTNGIAVPAA
>A0A8F6HIZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingosinicellaceae bacterium|TrEMBL
MSNLTLAQMNEAARAVSPPLFADLPGDIGVSFEFFPPKTDAMAETLWNSVETLRPLAPRF
VSVTYGAGGSTRERTHNTVARIVRETGIPAAAHLTCVDASKAEIDEVARAYWDAGVRHIV
ALRGDPPRAGERFAPHPDGYASAADLVAGLKRVADFEISVGAYPEPHPDATNSATDIDYL
ARKFDAGAVRGITQFFFEPDTFFRFRDAAAARGIDAELVPGILPVSNFAQLRKMAAGCNT
DVPAWMARLFDGLDDKPAARQLVAATVAAELCRRLYAGGVRHFHFYTLNRAELAYAICHM
LGVRPDATKQPQELAA
>A0A6P4I623|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila kikkawai|TrEMBL
MVSNDIHDHFYSGSNGGFNLSPDIFKEKLDAAGTLSTVLRLKRNTDLIPAAHLTCVGAPR
EAVDDLARCYRDAGVNHIVALRGDPSAGAVDDSPRPGGYTYASDLVTGLRRIADFDISVA
AYPETHPTALSPEADLDNLKRKLDAGATRAITQYFFDSEIYLRFLDRCLAAGITAPIIPG
IMPVSNYEQIVRFSAVCGVTVPAWLRYLFDGTAKNPELRRIVASMVAVEQIRTLQTYGIN
EFHVSTLNRADLTYAIAHILGVRPMQTNASHNVTGLLEKTEVPDERETPADFDSTAWAQE
GAPPFMLRTLFG
>A0A8J7YNP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sysuiplasma superficiale|TrEMBL
MLHTGRLERKLRQHYFVVTCELAPPQGATIEPLIKKAEAVRNHVDAANLTDCTSAMVRMS
SLAASVTVMKAGIEPVMQLTLRDRNRIGLQSDLLGASALGIRNVLCLYGDPPSAGNEKDA
KPVYDIGTDTLISGIRRMRDESLLMGGGKLTFPPSFFIGAAASPTEEESSKRIERIKKKV
DAGAQFFQTQPVFDLAVFESFMADMNSSGLSSAAPFIAGVMPLKSAKMARHIREEVHGIT
IPDDILERMERSTSPEETGIRIALETIEQVRKMRGVSGIHIMTVAWENVIPVIVERAGLT
PGDSLP
>M5BQ62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14)|TrEMBL
MHQEKVDIALREAKANGCRNILALRGDPPSGQEEWTSVEGGFQHGVDLVRHIRREYDDYF
DVSVAGFPQTIQLPEAEAKQEMQWLKEKCEAGANFIFTQMFYDADMFIRWVKAAREAGIT
VPIVPGINPIQTWNGFIRATSLSGTDIPQDLMGILEPHKNNDEKVRELGTKIVADLCRKI
LDADIGIRGLHFYTMNLEKGTKMLLEELNLVPRVETIKPLPWRQSLTPTRRTETIRPIFW
ANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELDGYGIWIKQTPEEGRKIWGTPTTMDDI
KDLFTKFCSQQIKALPWSDQPPTTEMLVIGQQLARMNELGYLTINSQPAVNGARSDDKAF
GWGPKNGYVYQKAYLEFFVHPAQLQALIKRIERDTNVTYYAINKQGDLKTNSTSEGPTAV
TWGVFPGKEVVQPTIVEAVSFMAWKDEAFELGCQWAKIYESGSPSRKLIEGMMDEYFLVN
FVHNDFHDREAIFRPFFADAGLKTNGNSEIPVVNGVKHSNGLVNGHSTAVHA
>A0A2M8YHX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. 67|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVQRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGANAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAATTALWQRLVK
>A0A2C7A7K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas rhizosphaerae|TrEMBL
MRFLDRCLAAGITAPVVPGIMPVSNYAQAARFSAMCGTSVPAWLGALFEGTEDDPEIRRM
VASIVAAEQVRTLQANGIDEFHFYTLNRPELTYAIAHILGVRPRDGASAPPAAGRP
>M5DYX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium saccharolyticum subsp. saccharolyticum DSM 6643|TrEMBL
MKIKNIFEKKEVVFSLEVFPPRSDVPIENIYQTLEELKDINPDYISITYGAGGGVRKNRT
CKLSSIIKEKYDVEALAHLTCINSNQKSINKILTRLEEKNIKNILALRGDKPVAGEVIGE
YNYAYELVDHIKKNNDFGVAAACYPEGHLETESIDQDLEYLKQKVDSGVDYLISQMFFDN
SLFYKFRRKAQKKGIDVPIEAGIMPVINKKQVARIIELSDAYFPAKFKKILNKYEDNPEA
LRDAGIAYAVEQIVDLISSDVDGIHLYTMNNPYVARRIKEAVGSLINHINGQEIQKVV
>A0A444KGI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.039.01.1.1|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFVDFGVTRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>A0A3A1YXS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas maritima|TrEMBL
MSSSRALSLEFFPPRDENARGKLTAAAKELEVLNPAYVSVTFGAGGSTREGTADAVDLLQ
KLGYEAAPHLSCIGASRAVLGDILQYYKDQGVRRLVALRGDLPSGMGMNKGELHYAVDLV
RFIREQTGDWFHIEVAAYPEVHPQAKGARADLNHFVEKVRAGANSAITQYFFNADAYYDF
VDRAREKGVGVPIVPGIMPITNHNQLVRFSDMCGAEVPRWIRQRLSDYGDDLASIRAFGA
EVVTRLCQDLLDQGAPGLHFYTLNNAGATLAIARRLT
>A0A2J8DJ10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium dahliae|TrEMBL
MDKITDKIAALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
AFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPPRKAE
YQDAVDEESDDDEDFVWATDLVKYIRKNHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVEKTQAGADFIMTQLFFDIDAYDHFEQVLREHPSGAFKTIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDALMARLDAVKGDDEKVKEVGVDIVSELVDQIRAVKSKRTTGPQGFHFYTL
NLEKAVSFILERTNLIPDKEQEDEEAVIDDATTPPVVPTVQINGLHPGSHHRPGRRQSSI
GSDPHNRVIVSSASNHAYETNPEGAGLPAEPIDTRANTLAISEGEGVLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVTQAVRLWGHPKSSEDISTLFIKHIRGELSAIPWSEE
GLSPETNIIQEQLIELNTRGWWTVASQPAVNGVPSRDATFGWGPSHGFVFQKAFVELFLP
AADWKVLSERLTGPEVEGTVCFYACNGNGDFATSDDSGGLVRTAVPASTNAVTWGVFPGK
EIITPTIIEEVSFRAWSEEAFKIWGEWSRVYGRGHESEKFLKSVKDEYWLVNIIHHDFVE
TNALWDLLRG
>A0A5N3XSY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muntiacus reevesi|TrEMBL
MDRPKPKVFPAGHCCPSLGMRASEAGSRRFSVPPSIRNSAMVNEPRGNGGPGPRLEGSSS
GSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRFD
RMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITGH
LHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKGH
PEAESFEADLKHLKEKVAAGADFIITQLFFEADTFFHFLKACSEIGITCPILPGIFPIQG
YHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFY
TLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGAELTSEESVFQVFAHYLSG
EPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGWG
PSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNL
VDNEFPLDNCLWQVVEDTFELLSRPPQDERKTEAP
>A0A0Q4IX25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf230|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGLSFEFFPPKSEKMDAQLWDAIRTLEPLRPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQPHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPTEKVAAA
>A0A7V5JHH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichales bacterium|TrEMBL
MESQKNFSRSFSFEFFPPKTAEGREKLETVLAELGALHPDYFSVTFGAGGSTQQGTYETV
LAIRDAGFEAAPHLSCIGSTREGIRAILHQYLDAGIRRIVALRGDMPSGMHEAGEFRHAN
ELVAFIREKTGDRFHIEVAAYPEFHPQAPNAIADIDFFMNKVRAGANGAITQYFYNVDAY
LRFIEACEARGLDVPVVPGIMPITNYVRLARFSDACGAEIPRWLRKRLEAFGDDTDSITA
FGIDVVTALCERLLAEGAPGLHFYTMNRTEPTRTIWRNLGLPK
>I3SJD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Medicago truncatula|TrEMBL
MKKLSRHMGIHLGTEMCKKIMAHGIKTVHLYTLNMEKSALAILTSLGLIEESKISRSLPW
RRPTNVFRVKEDVRPIFWANRPKSYISRTIGWEQYPHGRWSDSGNPSYGALTDYQFMRPR
AKDKKLIEEWAVPLKSIEDIYERFRLFCLGKLRTNPWSELDGLQPETKIINEHLEKINTK
GFLTINSQPAVNGEKSDSPIVGWGGPGGYIYQKAYLEFFCSKEKLDALIEKSKDRPFLTY
MAVNKEGIWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFNVWKDEAFEIWSRGWASL
YPEADASRKLVEEVGSSYFLVSLVDNDYANGDLFGVLADF
>A0A832H392|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillatoriales cyanobacterium SpSt-402|TrEMBL
MLVSQSAISSFQAAAQSGEFLITAEVCPPKGGDPTHMLEMARLLKGRVHAVNITDGSRAV
LRMSSLASSVLLQQIGVEPICQVACRDRNVIGLQADLMGAQALGIRNVLALTGDPVKAGD
HPTARPVFELEAVRLLQLIRKLNTGFDFNEKPLPDGATELFVGAAVDPQCGSWSGLQRRF
ERKLEAGAQFFQSQLISDFEQLEKFMTQIAAPCHKPILAGIFLLKSAKNAQFINRNVPGV
QIPDHLIDRLERASDPLYEGMLIAAEQVRAARDLCQGVHMMAVRREDLIPKILDLAGIAP
LQETTASSSNGITPAIGS
>A0A285PW23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum hallii|TrEMBL
MKNDGMDEMNIREYLENHKLLTDGAMGTYFDTVEKENYICSEEANITNPSLVRQIHKNYV
KKGAQLLRSNTFLANRETLLSLQQNRAEQFQNVSLKELVTKGYRLAEEVAREAYSESYPV
FPAADIGPILEEKESEETDILQQYYEICDSFLEAGANIFVLETFPDTEYVLKMAEYIRQI
CPEAFIIGQFSLTPTGYSRTGFHYKTILRDAVQSGLLDGAGLNCGIGAAHMKRFLEAYIE
EYGVPEDMILTALPNCGYPQIVRGHVIYSDSVTYFGEKIKEVSELGVRVLGGCCGTTPEY
IGEIYRTLFQAEHTLKVPTRIVWTDAAGRIQKRQEQLAHIKSAEGKNKTIKKEQVVNTFR
RKLEKGELVCAVELDPPFDANDTKLVNGAKALLSTKADIITIADSPLARSRADASLMAAK
IKMQTGMDVMPHLACRDKNRIAIRSGLLGSYVNEIRNYLFVTGDPVAREDREFTKSVFDF
NSIRLMKFAQSMNQEIFADDMIFYGGALNQNGASPENIAGRMIKKIEAGCSYFLTQPVYD
EEGIKRLAFLKERTGAKILIGIMPLVSRRNALFIKNEMPGIYVPDRVVEKYKENASREEY
EEAAVEISKKIIEMGKEVGAGFYFMTPFNRVSLVKSILEYV
>A0A0A0FB57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli G3/10|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1H6M2M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bathymodiolus azoricus thioautotrophic gill symbiont|TrEMBL
MKTSFEFFPPRTEKGKQTLHQVRQELSSINPEYFSVTFGALGTTQEATLETVLDIQKNDT
VVAAPHLSCIGSKKEIIIELLDQYKAVNINRLVALRGDIPSGVRDIGDFHYANELVEFVK
SQYNNHFHIEVAAYPEVHPESKNRQTDLQHFADKVKAGADGAITQYFYDAEAYFKFVDEI
EKLGVSIPIIPGIMPITNYTQLVRFSNMCGAKIPNWILKKLELYQDDLDSLSTFGLEVVT
NLCQTLKEQGVNNFHFYSMNRSQPSLEIAKHL
>H8FSE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum molischianum DSM 120|TrEMBL
MNPVSSVELPIVAAHRPVSVSFEFFPPKTDKMLESLWDAVRRLEPLSPAFVSVTYGAGGG
TRDRTHEIVSRIAHETSLKPAAHLTCVGHSRGEVDDIARRYWDEGIRHIVALRGDMPDGQ
PYQPHPQGYDYAVDMVAGLKRIADFEISVAAYPEAHPDAPSPDFDIENLKRKIDAGATRA
ISQYFFDPAVFLRFRDRCAAAGISVPIAPGILPVTNFAQVQRFSAACGTTVPDWLADLFE
GLDDDPETRHLVAATVAAQQCRILSAAGVDLFHFYTLNRADLVYAICRVLGVRPQTA
>A0A374TSZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. TF10-11AT|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFNTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A4R5YAU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria rosea|TrEMBL
MPIDPPHAGPAAALLRDFSLEMTGKDVPALEEAAAVVPAGTRINVTFLGNEDLGMRVAAA
RAVREHGFVPVPHLSARRLRSQGELEEFLAALAEVGAAEHVFVVGGDPETPEGPYPDSLS
VIRTGVLPRHGVRGVGVSGYPEGHPGIDDAALWSALTDKTAAIREQGLEPEIITQFGFDK
DPVLEWLAEVRRRGVDTPVRIGVPGPAGVRRLLGYARRFGVGTSAGIVQKYGFSLTNLLG
TAGPDRFLRDLAAGLDPAVHGQVLLHFYTFGGLRATAEWVREFGTDGGTP
>A0A2G3CIX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum chinense|TrEMBL
MKVIEKIQESIKDDKVVFSFEFFPPKTEDGVDNLFERMERMVSHNPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALENIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGLATPEAYEKDLAYLK
QKVDAGADLIVTQLFYDTDNFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKIMASGIKTLHLYTLNMEKSALAILMNL
GFIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDEFPHGRWGNAQNP
SYGALSDYQFMRARSRDKKLQEEWAVALNSVEDIYERFMNYCLGKLRSCPWSELDGLQAE
TKIIDEHLSNINTKGFLTINSQPAVNGAKSDAPLVGWGGPGGYVYQKAYLEFFCSREKLT
AVVEKCKAFPFLTYMAVNKQGNFISNIHQIDVNAVTWGVFPAKEIVQPTIVDPVSFMVWK
DEAFEIWSRGWAQLYPENDPSRKLLEQVQNSYFLVSLVDNDYINGDLFAIFKDI
>F7YK19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio anguillarum (strain ATCC 68554 / 775)|TrEMBL
MIDWRKNATGRNKMGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSAQMEETLWNSVHR
LKTLQPKFVSVTYGANSGERDRTHLIIKEIKEQTGLIAAPHLTCIDASRDELIQIADDYW
HNGIQNIVALRGDIPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQSDLV
NLKRKIDAGANRAITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQASRFAAQN
NVKVPGWMAKQFNGLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALC
HTLGVRPKA
>A0A3D5HLT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MTSISFEFFPPKSAEAEVKLWDVINELAAIKPDFVSITYGAGGSTRDRTHQCVKHLVTKT
DLKPAAHLTCVAASKSEVDEVIEDYASAGVKHIVALRGDMPDMEAFSPHPDGYNGSVELV
DALAQRGGFDITVSAYPEKHPESGDMQTDIDLLKAKIDAGATRAITQFVFDTEQHYRFRD
VLADNQINIPVIPGIMPTTNFKGVLRMSEACGASVPIWMKSKFDGLDDDFESRRALAIKL
ATNQCRDLINSGFENLHFYTLNQVTVTKAVCKTLSLEKVGV
>A0A558IHQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium aurimucosum|TrEMBL
MSPRLSASAPLDQISEDTPKRPQRTALSFEVIPPRHDADAAKIDRLLATLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTEEELVGWIDTLVDAGVRGLLALR
GDLPEGGMPEGHLPHADSLVRLIRRWESDRVARLAAGRLAVGVACYPNGHAESATPDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTKVLDRLAAATSPEEEQEIGMQITASLAKSVMNAGADGLHIYTHNNPDITTDLL
HRIGVIP
>A0A2E7DFH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTVTREQVTSLLAEFSVEITPASAAKVEDFSAHLSPGTTVNVTMLPGSSFADTIDVCDRL
YHAGYNAVPHIVARSIENAVDLERYLDALACRATIKTVLVIGGSVDRPVGVFNNTMQILK
LGLLENYGIRRIGVAGHPEGSPDINDRALAKALAEKNAWARDTDAEVYIATQFCFEVKTI
TTWERRIWNEGNRLPIHVGLPGLATLKTLIRFAQMSGVGPSIRVLTRQARNIAKLLVVQE
PDTVVAGLARATAANPDTLIKNVHFYPFGGLAKTAAWANAAASGSIRPKPNGGFELLDNT
GKQFQAPS
>A0A831UFP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter metallireducens|TrEMBL
MNFIESLKNEVLVGDGAIGTMLYAKGVSLDANVEHLNLVRPELVLELHREYLAAGARVIE
TNTFGANWTKLSAIGLEKREREINLRGARLAREAAVGTDAFVAGSLGPLVRVKGDERELS
PAETTEIFRRQAQALAEGGVDLLILETFTDLGQILRALEAARETGLPVVASMAFLENGRL
AGGADVERAVGELTAAGASVVGANCGAGPLEVLGTIRRMAVATALPVAAYPNSGFPEYVN
GRHVYRTTPDYFAERAAEMVAAGAALVGGCCGTTPEHIRRLAQRLAGLRPAARTVAAPAV
PAEERREEVAAAEGFLARWGKEPIVTVELDPPKGFDCAKIVEGSRALKAAGADAINIAEN
PLARIRMGNIALGHLIQQEAGIEVIVHVTCRDRNLLGLQSDLMGASLLGIRNILAVTGDP
ARIGEQAGATSVYDLNSFTLIKLLADLNAGVNALGNPLGRGAGFTIGCAFNPNSQRMEVQ
AERLARKVANGARFVQTQPLYDLGRLDEMLARTAHLGVPVLPGILPLVSERNCEFLHNEV
PGIVIPEEIRVRMRGKEKEAGVREGLAIAREFIDAARNRVGGFYLIPPFGRYGIAVELVR
HIKEK
>A0A4R3TED2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. PhB57|TrEMBL
MTFAERPVSAPLFEDLPGDISVSFEFFPPKTEKMEEQLWDAITQLAPLDPSFVSVTYGAG
GSTRERTHSTVSRLVRETQLVPAAHLTCVGASKDEIAEIADQYWEAGVRHIVALRGDPPP
SSGGVFTPHPQGYAGAADLVAGLKARHDFDISVAAYPEVHPEAASADADLDNLKRKLDAG
ANRAITQFFFSTDAYFRFLDKVLAAGISAPILPGIMPVTSFAAIRRMSGNTEIPGWLEIM
FEGLDERPGPRALVAAVAAADLCRRLYEGGVRDLHFYTLNRAEQAYAICQLLGLRPKPGA
>A0A8C1BBN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MQDYSWIHTCESSKSDSSGVSNSGESSKESSRCSTPVQDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGGMNGDFDGDFFCVNLVTFRRP
LPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLF
YLKSKSPKEALLQMWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNL
LKDELEKVNCRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALL
QVLKKYEPRVNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDE
AFALWIEQWAKLYEDESPSRMIIQYIHDNYFLINLVDNDFPLDSCLWQVIEDMFTLLDSP
PETQEEGSQS
>A0A8C2C7B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MSCEQYQNMLYSGYSDVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMK
RRIESGDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSM
MIASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDG
GFNYATDLVKHIRCECDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGAHFIVTQLF
FRAETFLKFVKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDN
DAAIRSYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWA
VSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKS
KSPKEALLQMWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDE
LEKVNCRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLK
KYEPRVNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFAL
WIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQ
EEGSQS
>A0A8C1LMM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
DWEEVEGNGGKAFLCYYSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRWFSL
EFFPPRTAPGAVNLISRTNITPTLHRSGICFLNEWTFCSLCVRFDRMGSGGPLFIDVTWH
PAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMAL
RGDPIGKDWVEEDGGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKE
KVDAGAHFIITQLFFRAETFLKFVKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEV
PEEIMQVIEPIKDNDAAIRNYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQL
GLWAEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPA
FGELTDYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWN
DDPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFF
TSSENVTALLQVLKKYEPRVNYHIVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVD
PVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVI
EDMFTLLDSPPETQKD
>A0A8C1LK30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGKDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIITQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQVNTILRARLCHVISCFYIDIMK
>A0A256HI10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halorubrum sp. Hd13|TrEMBL
MSAGTQAIKRSDGVGALLTDARFELMPFESFEDEIRHLPDDATIAVTTSPQLGIDTTVER
TEQAAALGYDVSPHIAARYVEDRDHLDEIAERLTDAGVTDIFVPGGDREEPAGEFESAHD
LLVALDELGHSFDEVGITGYPEGHDFLDAEALSDAMAKKSPYATYLVTQLCYDPDAVLEW
IDDIRDDGVDLPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVRQLVGSRG
VYKPDDLIDGLAPYADDDHYKIRGIHIYTFNQTPDTESWRTERLGR
>A0A1Y2B470|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naematelia encephala|TrEMBL
MHLTDLIARRNTPFHTYEFFPPRTEAGFVNLLDRIRRLATAPLPPPLAVSITWGAGGSTA
ERTMELAEQVTRLGLEVILHLTCTNMEKEKVDKALEKARALGIQNVLALRGDPPRSEEYA
ISPISTPDYFTHADDLVRYIREQHGDYFCIGVAGYPTPHPDSEGPEDDLHWLKIKCDAGA
DYIITQLFYDVEGFEGWVKTCRKNGIDVPIIPGVMPIQNFASFRRLVNLTQCSVPDSIMT
ALEPIKSDDAAVKRYGAQLATGMVQRLVSSGLVPGVHFCTLNLEKSVRTILENLGWTPES
SNRVQSSPLPRHNQLIEDDTDAPQGLSVPNAANFPIKQMNGLSISPSEASQLAEWGLTNH
ALPPAPKKGLGNSAAAQAPSAEDSWDEYPNGRFTDVRSPAYGEIDGWGSGLKITAAQALR
DWGAPTDAAQLSDLFTRYLESDPSAPTTPFCDLPLSDESATILPYLIKLNSPQLQHWTVG
SQPAVDAAHSEDPVLGWGPRGGYVFQKAYVEFFVKREQVERIHERLKDRTDGQISMYAAN
KQGEFITNTLKDAVNAVTWGVFPGQEIVQSTIIEEESFRAWKEEAFDIWTEWSLLYPRLS
PARKLLEGIASEWWLVSLIHHDYKAPDALWTFLLGDEVAA
>A0A423WH66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Valsa sordida|TrEMBL
MDKITDKIAAMPPDANYFSLEFFPPKTQMGFANLRSRLERMARALKPTFVNVTWGAGGST
AQKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALEDAKVLGIRNILALRGDPPRRAE
YMDENDEDDALGDEEFKWAVDLVKYIRKSHGDYFCIGVAAYPEGHADESHPLGQSMEHDL
PSLVEKVQAGADFIMTQLFFDIKAYDRFETTLREHPTGAFKNITIIPGLMPIQNYQMIKR
TTKLSHAGIPDDLMARLDEVKRDDERVKLVGVDILSELIEQIREIKSRTPGPKGFHFYTL
NLEKAVSFILERTGLIPPESPAGENALAVDDLITSVPTVEVNGTGSNGTGSTSQQHLNIR
SASRRQSNVSSEPRNRVIVSGERTPSNPEYEATQLEASRPYEPVHSRANTLAISEGEGVL
GREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSVTAARSLWGAPSSVDAISTLFIRHL
QGDLRAIPWSEAEFNDETGVIKDQLLALNQKGWWTVASQPAVNGVKSSDPTFGWGPANGF
VFQKAFVEFFVPADQWKRLHDKIARPEMKESIWFYAANAAGDFVSQDFSGEPDQDMQEVG
TNAVTWGVFPGKEIVTPTIVEEVSFRAWAEEAFGIWGEWAQVYGKGSEAARFLEKMKGDL
WLVNIIHHEYVEKDALWDFLKSA
>A0A1I7A0F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. ov118|TrEMBL
MSPPSLIDAHPNLAGAAPVALSYELFPPRSPAAAESLWTTIGELEATDPDYVSVTYGSSG
SNHGTAIELINRLVQETTLRPLAHLTCVGNSPQELAEIIGELLDVGVRGILALRGDQPKD
GGAPPEGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLM
AKQRSGADFAITQVFFHTEQYADLLTRARRAGVTIPIIPGVMPLTSLRRLARLAELTGVE
PQPELIERLAAADTDAERIRIGVSATVDLANAALDAGAPGLHLYTFNEHAAALDVLDKLA
LPRPRTGRHSGNRNSGARIDASRHAATGQLAS
>A0A1M5A104|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lampropedia hyalina DSM 16112|TrEMBL
MTQAGSAPALSLEFFPPKTAAGVEKLRAVRASLYAMQPEFCSVTYGAGGSTQAGTFSTVA
QIIAEGGSAASHFSCIGANRDKVRTELAELKAMGVRRLVALRGDLPSGYGMGGEFHYASD
LVEFIRAETGGDFHIEVAAYPETHPQAHSPQSDLNAFAIKARAGADSAITQYFFNADAYF
RFVDDVRKLGVEIPIVPGIMPITSASSLLRFSDACGAEVPRWVRLRLQSFGDDTASIKAF
GEDVVAGLCQRLLAGGAPGLHFYTMNQSEPTLGVLRRLGLARG
>A0A2M7JRT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_8_14_3_um_filter_45_9|TrEMBL
MKTKSNIEKILESGGFVLTSECGPPRGADAEVIRKKGNILKGVVDAVNVTDNQTSVVRMS
SFSSCIILKEMGFDPILQMVCRDRNRIAIQSDILGAGALGINNILCLSGDHQKFGDHPMA
KNVFDMDSIQLIHTVKTMRDDGKFLGGEEVKGRPILFIGAAENPFADPFEIRAARLGKKV
KAGCEFIQTQCIYNIEKFARWMEMVRERGLHERCAILAGVTPFKSVGMAKYMKNSVPGMD
VPDAMIERMRGVPKERQSEEGIKMCVETIQKLREIPGVRGIHIMAIEWEEKVAEIAKAAG
LLPRPQP
>A0A1Q3YHQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium 66-26|TrEMBL
MHLPVSFEFFPPKTPEGVGKLRDVRQQLYALQPEFCSVTYGAGGSTQAGTFATVREVLAE
GVPAASHFSCVGATRETVRAQLAELQAMGVKRLVALRGDLPSGYGMGGEFQYASDLVAFI
RAETGRHFHIEVAAYPEMHPQARSPEADLKAFAAKVRAGADSAITQYFFNADAYFRFVDE
ARRAGLAVPVVPGIMPILGSTQLLRFSDACGAEVPRWLRLRLQGFGDDVASLRAFGLDVV
TRLCEQLVAGGAPALHFYTMNQSAATLQLCRRLGRAEQA
>A0A1Z9EPY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium TMED123|TrEMBL
MLKETNLVPAAHLTCVNAKREEVDAVARAYWQAGVRNLVALRGDPPDGNNSYKPHPGGYA
YAVDLVAGLRRIGDFDISVAAYPEIHPQATGAEADIDNLKRKLDAGATRAISQYFFGAEP
FLRFMDRVRAAGIEVPIIPGILPVQNFAQVVKFSNLSGISVPRWMAELFDGLDEDPETRR
LVAATVSAEQCRQLHAQGITDFHFYTLNRADLTYAIAHILGLRSNNTAGDLRTRST
>A0A7T9K6F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIDHINQAKDTLISFEILPPLKGKGIQSLYKLMDELMEHKPSFINVTYHRSEHVFKKT
ATGDFKKVIVRKRPGTESICAAIMNRYNVDTVPHLICGGFDINETEDALINLNYLGIDNV
LVLRGDAAKNETNFEPEPGGHKYAIDLLRQVGNLNAGVYLEEDLKHSIKTKFCIGVAGYP
EKHFEAPNMETDLQYLKQKVDAGADYIVTQMFFDNTKYFAFVKSCRDMGINVPIIPGLKP
VYSVKQLTVLPKVFHIDLPTELSGEMIKCKSDEEVEKLGTEWLYHQSVELKKSGVPVLHY
YTIGKPGVVCDVVKRLQ
>A0A2U2SE60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPIFTPGRRWQPAYSPFKPESFTSRLMENIEYAIKGPLFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGSTPERCYVDKTRPCIWYEIYARAFKLGREEKLLEVLPPLDWDKVGEETW
RDVITCIKKNGGGQVLKSLLFDQGENRYKTWNLIFRTVRQPEWWQGDDQYHPPAYSEPVS
NLERAFKAGQFVVACEIAPPLGMSTKKLVETIQLVKPYVTAINFTDNASATPRMTSWACS
KIAIEAGAEPVMQIAARDRTRASLQGEILGATAMGVRNVLCVTGDSPVLAPPPRGRMDIN
DLDSIQMIWILRRMRDEGRYLDGREIKFPPKFFLGAAASPFASEPKFQAIREHKKVNAGA
QFFQTNLVYDIERMEIWLNALAKRNILDKVYIMIGITPLKSAKMTRYMTQVPGVFVPETI
LKRMEEAEQAGNAQEEGAQIALELIEKIKTYQTQGIHGLHIMPVGWEDIVPRLVREAGLL
PPGFAAPEPAVAVAH
>A0A3D2UTC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MNLLETISNKTLLADGAMGTMLHARGVGFDKSFDELNLTNPAAVAEIHRAYIEAGAELII
TNTFSANRFKLTKHGLQDDLVEINRAGVELAKRVVAASFKDVLIAGDVGPLGVRIAPYGR
VKLEEAREAFAEQIKALADAGADLIIIETFSDLYEVGEAIKASKEVCNLPVIASVTFTRD
DRTLLGDDPAKVATRIADAGADVIGVNCSGGPSQLLRILKQMKQAVPNGKFWVKPNAGWP
EQVSGRIMYPADAEYFGEYALLFREAGANIVGGCCGTTPQHISAMKKTLESAVRESIQEI
SILPEDEITSEPAQQPTQLAQKLSNQKFSICVEMDPPRGLSTHKLLAGASLLHDSGADVI
NVADTPMARMRMSAWAVCDLVQRQIGVETTLHFPTRGRNLLRVQGDLLAAHALGIRNIFV
VMGDPTSIGDYPEAADNYDLVPSGLIKLIKQGFNMGVDHSGTSIGQPTNFFVGAALNLCP
QDMETEVKNLHRKIKAGVDFFLTQPIYRKDDGPKLIEAYESKHGKLNQPILAGILPLVSA
KHANFLHNEVPGVFIPDETLKRIESAGDGAAKAGVELAVDLIQGIKSWASGIYMMPQFHR
YDLVSDIIMNVKE
>A0A3M1BEL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MSMTRDEFLAFLDEQVRPVLADGAMGTMLHERGIGFDECFDALNLTNPAVVGDIHRAYIE
AGAQIIYTNTFGANRYKLAEHGLEAQVVEINRKGVELAQRVVAASFRPVLVAGDVGPLGV
RLAPYGRVQPQEARAAFAEQIAALCQAGADLIVLETFSDLYEIREAVAAARQVCDLAVVA
SVTFTRDDRTLLGDTPAAVARALMASGADVIGANCSGGPAQLQRVLEQMRQAAPQARFLI
KPNAGWPEQVAGRVMYTAHPDYFADYAETFARLGVRLMGGCCGTTPQHIAAMRARLDALP
PDLEIQPIVTSPRLQPRDLAPKGPTRLAQRLAEGKFTVAVEMDPPRGLAPHKLLAGASLL
KEAGADVINVADSPMARMRMSPWAVCDLIQRNVGIETTLHFPTRGRNLLRVQGDLLAAHA
LDIRNVFVVMGDPTAIGDYPDAMDDYDLAPSGLIKLIKQGFNMGVDHAGSDIGQPTTFFV
GCALNLLPANPQREMKVLRRKIRNGADFALTQPIYDPRKAHEFLQRYEETYGPLEIPILA
GILPLYTARHAAFLQNEVPGIIIPPEVMSRIEAAGDAAAEEGKRIAIELAQAVKPWAAGI
YIMPPFHRYDLVAEIIEAVKDD
>A0A660UXN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MQKKRLREALQDKSSFDVTVELASGPDFDFSPVQKFLTGFRKDEGASVPNEFNLVAITAT
DNSGGTPNIETCDMYRRMTDADLLGHLDYIPHISCKDRNVDMIASTLAAYKAAGIESILV
ITGDKSVNSKSVFEHESVTFLQMIKEMNAQAYARASADDLDSVHQFCAGAAVSPFKYTEA
SQMQQYYKMEKKIACGAEFLVTQLGWDWKKSLELFTYLKENNIETPVFGNVFFLSTLNPA
ARLMNSLKLTGCFVSDEFLAKLNSETIDEQLDRAAQQVAMYKSMGAAGVDIGSVHDYDMF
IRILQRAVEIGDDWRMHKDNLSWPQEGGFYLYDDGGVRRRLSRPRKTLSQRHFNLVHDIL
LDEDCRGFKVFRGVMGALGARKGKGFTYRSFDAIEKAFKYLLFECQACGDCYLPENFGLC
TIGKCEKGLANVPCGDATVEGFCGNNLEMQCVGELVYRAAAATEGGIEKWRKTICKPRMH
ELEQTASVLNHLFGLDHSARCSLKSVGESIHSLIPTVGSIMKQLHERGPDAYAKHSRQLE
YIKAMIELQAARGAEFVAVNVDAFAKEDVEAAKEMIVQYARMVRKWAGSVAICIDSTYSG
ILTAGLKEWYNTKAKVSAPLLALPSADALAAVGALKREYDFGVVVALDSDGDSVEGLHSQ
AGDIFDRATGEYGFKADDVYFEVNATAVAKDLDEAAGAPGGIYVSFETMKKIKKDKRLKG
CHCAMRPSLVAMKLPRSIGVLRAYIAKAMEYGLDTAFVDVSRRFGHVDADPGLVELIDAF
AKKNGTAKNKEKAQAMLDEFCSKNAKKKK
>A0A7C3CU97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MAQLNLSFEFFPPRSGEMAAQLRDAYRQLARLDPVYFSVTYGAGGSTRDKTVETVLEIQR
ETGVETAPHLSCIGSTREEIRGLLNQYRDQGIRRIVALRGDLPSGMHADGDFRYASDLVA
FIRAETGDHFHLEVAAYPETHPQAASYPDDLQHFVTKVEAGADGAITQYFYNADAYFHFV
ADCRDLGVTIPIVPGIMPVTNYTQLARFSDLCGAEIPRWMRKRLEAFDGNLEAIRAFGIE
VVTELCRRLIDGGVPGLHFYTMNRAEPTLTICRNLGLA
>A0A7Y2XDF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibacter sp|TrEMBL
MKVTEHIHNAKGKTLFSFEIVPPQKGQNIQQLYNNIDPLMEFKPPFIDVTTSREEYVYIS
KENGLLEQKITRMRPGTVGICASLKYKYNVDAIPHVLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDAMKHETYFSPSKDGNKYASELVTQIKNLNKGKYLHEIIETTYNADFCIGVAGY
PEKHLESPSLDSDLRRLKEKVDAGADYVVTQMFFDNKKYFDFVEKARDIGITVPIIPGIK
PIAIERHLQVLPQVFKLDLPELLISEVEKCTNNKQVRQVGIEWAIEQSKELIAKGVPVVH
FYSMGKSDNIKEIASAVF
>A0A350G0T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPGFTPGRRWQPAYSPFQKESFGEHALRVLEYSVKGPLFGCRMCGNCLLAETALICPMEC
PKGLRNGPCGGSTSEYCYVDESRPCVWYEIYDRSFRWGREDVLLEVLPPLDWEKVGKDSW
GAILRNAGRIGVKKIFSGLLFAETRAQTLDGIFRPVRQPDWWQGDSKYHAPAYAEPASDL
QRRLAAGEFVFTCEVTPPLSSSTDKLIRNIDMVKPYVAAVNFTDNQSATPRMTSWACSQV
AMDQDAEPVLQMSARNRSRGSVQSEIIGATALGIRNVLCVTGDSAKMSPSPRDQMDINDL
DAIQMLWVLRRMRDEGKYLDGREIKNPPMFFLGAAASPFSSNPKFQALREQKKVNAGAQF
FQTNLIFDVDGMELWLNELAKRNILDKVYILAGVTPIKSLKMAQKLSTIPGVHLPQHILE
RMEVADHAGNAQEEGVQIALEIIREIKGYDKQGIHGIHLMPIGWDEIVPRIVRDAGFISK
DIQINNPARELEYAHSLEK
>A0A7Y4CI28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio tubiashii|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELIQIADDYWANGIQSIVALRGD
IPPGGGKPEMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A7Z9ZH91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MKLTDLFANGKFVVTSEIGPPKGVDIETMMEDAELLRGKVDAINVTDQQSSVMRLGSLAV
CHLLKKRGLEPVFQITCRDRNRIALQSDLLSAYVLGIENVLCLTGDYVSLGDHLGAKPVF
DLDSVSLLHVASELQQGRDMAGQKLRGSPDFCLGAVVTPGANPLELQIMKMEKKVRAGAQ
FFQTQAVYDPRRFEEFMNQVKHLNVPVMVGIVLLKSAGMARFMNRNVAGVHVPESLIDEM
DEAEDRVAKSIEIAARLIREMKDLCQGVHIMPIGWEKHVPAVLEAAGLL
>A0A3C0VD47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MGRAAPPQASTPGLRRCGRYHRIGTRTGRGAHAAAPGERMPGDFLAALGERVLVCDGGMG
TSLYARGVQINACFDELNLSQPHLVREVHRGFLSAGADVLETNTYLCNRFKLGPHGLDGR
VREIILAGVRLARDESRGSAWVAGAVGPLGAALEPYGRLAAAAAREAFRESIDAMIEGGV
DLLVLETFGHVEELLVAVAAAREARAAAGLSLPIVAQLACDRDGMTLGKTPVGCAAAMLR
DAGADVVGANCGVGPRPMLRCIQEMAVAVRAPLSAQPNAGLPEEVDGRLMYVSTPEYFVT
YAKRLIRSGVRLIGGCCGTGPAHIKALAQTVRALNPGRVAVAAAAVRGAMPEIRVLPAAE
KSNLAAKLARGRFVTSVELLPPRGNNPEKVRAAAALLRSAGVDAVNIPDGPRASARMSPM
CLASILQREAGIETVLHYTCRDRNLLGMQSDLLGAQALGLRNILAVTGDPPKLGNYPDAT
AVYDVDSIGLVRLIANLNRGLDVAGNP
>A0A6N7P5E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sp. SYP-B3965|TrEMBL
MNRTELLNNKIEQAESGIVFYSLTPPKITTEAERLITIAGNQVERLSNLDIDGLILYDIQ
DESTRTEKERTFSFIRTVSPEEYSRLYLKDLHIPKIIYKSIANQNSEQFTSWLKDNDDLG
TAVFVGASSKKEIDTTQFSLSDAYQVKMQHGKQLMLGGVTIPERHGKKGDEHIRIFNKID
SGCRFFVSQCVYNINDTKNLLSDYYYYASEEGKKMAPIIFTLAPCGSLKTLQFMEWLGIK
VPKWLFNDLKHSEDILEASIKTSLNIAHEILNYAANKNIPVGFNIESISIKKEEINAAHA
LLKDVLKLVRPSKESKTVAQLTSSESILTK
>A0A7C5EHF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MVSEDFLTALAARPMVFDGAMGTLLYETGWFINHAFDEANLKKPESVLAAHESYVAVGAD
IVESNTFSANRFLLGRYGVENLVGEINRAGVRLARQASGDTVYVAGALGPTGEAFGRFSE
EKAKEIRRAFDEQISALADEKPDLLVLETFHHLKEIQIALQAAREIFRGPIVAQMSFLAD
GALRDGSEPELVAERLAAWGADIVGVNCALGPQEVFEIVQRMIAVGIPTSAQPNAGQPRR
LDQRMLYMATPEYFGVYAKRFFKAGVRLVGGCCGTNPDHIAAVRGACAMACGAEEKRPTT
GEFRIQTLEEPGLEPLPVAERSAFARKVRRVWEERLDPNGPRRPLRGPEDFVVSVEVNPH
PGLTTERAVEGAKLLRDAGVDIVNIADGPRALVRMANWALGLTIKDALGLDFLLHVCCRD
RNILGLQSDLLGVHVLGVRNLVVITGDPPKMGDYPKATAVFDLDSVELLKLIDALNHGID
PAGKFVGEATSFFCACGAEPAALDYDRELRRLEAKIANGAELIMTQPVYDPVVLERFMSD
VEGFHVPVMVGLLPLASHKNAEFLHNEVPGMQIPSDIRDRMSAAGSGPAAQREGVRIASE
MLERVKDRVVGTYLMPPFSRYQTALDVLKVVGYGD
>A0A7V3JMK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSSSSDSVSFRQALSSGRFVYGAEVVTTRGFTPPGTPNQVQDLAAALLADPRIAWVSITD
NPGGAPMLPPDWLGRLLWDQRQRVVIHMTCKDANRNALEAAAWRYAAEGFDNILALTGDY
PTIGFGGVADPVFDLDSVGLITLLRAMNQGLRIPGRRGGSETLPPTHFYIGCAVSPFKRY
ERELVPQYFKLLRKIRAGAEWVIPQLGYDMRKFHEVKLFLAARGLQVPVIGNVYVLNRTV
AGMFHSGKLAGCVVSDSLMEEVQKQAASPDKGRKFFRELAAKQLAVFKGLGFAAGYLGGI
AKPESFFEIIDLAESYGENDWKDFLREIQYAQPGEFFFFEHDPDTGLSSPDRVNREYLAS
LKNPPRSRHVTLGYRFSRFVHGFAFERGKGIYGLLARLYRRWDRKPTFLSRLAYWLEREA
KHLGYGCQDCGDCSLPDCAYLCPLASCSKHSRNGPCGGSAGGLCELLDKDCFWARVYERL
KYYGESERMFEGPVVFYDARLKHTSAWANTYLERDHAGRPPEGVPPAPSAAPDPQKPPAP
PSPPGGT
>A0A3D1RA11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTEHLQQAKDTLISFEILPPMKGKGIHSLYDHLDPLMEFKPSFINVTYHRSEHVFKKT
VHNTFEKVVVRKRPGTESICAAIMNRYNVDTVPHLICGGFDINETEDALINLNYLGIDNV
LVLRGDAAKNESSFEAEPEGHRYAIDLLKQVVNMNNGIYLEEDLKNTSKTKFCIGVAGYP
EKHFEAPNMDSDLNYLKAKVDAGADYIVTQMFFDNEKYFNFVKRCREIGIGVPIIPGLKP
VYTRKQLNLLPKTFHIDIPSALELEMSKCQSDADVEQVGTEWLLHQSRELKKAGVPVLHY
YTLGRPGVVANVVKELV
>F7W701|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)|TrEMBL
MSGAAFKPQQHLGGANRTAVLHTGDGTRCHRDHWLPRRASLRQGAKEAKGFDKLPHATTF
PGVQYSTVILTTYIHRISPYRTEIRTIPSTMEKITDKVAALPPDSNYFSLEFFPPKTAMG
FANLRDRLERMARGLRPLFVNVTWGAGGSTAQKSLELAEICQRELGLTTCLHLTCTNMSR
RLLDKTLEDAKVLGIRNILALRGDPPRAAEYHDENDPEPTDDEEFSWAADLVRYIKKNHG
DYFCIGVAAYPEGHADQSHPREQSLEHDLPYLVEKVQAGADFIMTQLFFDIDAYEHFENT
LRGHPSGAFKDVLIIPGLMPIQSYQMIKRTTKLSHAKIPPALMARLDAVKGDDEKVKMEG
VAIVSEIIERIKEIKSRTHTPRGFHFYTLNLEKAVAFIAEGTNLIPPGTPEEDESAILPD
FPQLMINGSSVPTRSIQGLSTRKGSIGSDPRDRVIVANPRPSHPDYEASPSQAGLLAEPV
NTRANTLAISEGEGVLGREATWDDFPNGRWGDARSPAYGQIDGYGVSLHVTVPQALQLWG
SPKTTEDINNILIRHLKGELSAIPWSEEGFNAETEAIRDNLIKLNSKGWWSLASQPAVNG
LRSSDGTFGWGPHNGFVFQKAFVEFFIPSADWRALEAKLKQPDMKDVVCFYATNAAGDFV
STDTVNFRARMAADADGTTSEADRRPHEPSTNAVTWGVFPGKEILTPTIIEEVSFRAWSE
EAFGIWSEWAKIYEKGSDTQKLLEDLKEDLWLVNVIHHDYVERDGLWELLFQ
>A0A2E6HGZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFISEIHADKKALGQPTISFEFFPFKTPKGEAKFFNETLPSLMEARPDYASVTYGAGGS
TREKTLDIVERIQGDHGLTTMAHLTCIKHTQEEIGSILHDARERGIKNILALRGDPPPGE
NWSMTDGGFEFASDLVSYIKSQGDFGIAVAGFPEGHIDCKDGRKADWHHLVQKVNCGADM
VITQMFFDNSDYFQLSDFLAESGTNSPLFPGIIPVTNVEQIKKFSALCGAKLPGKFTARL
EELSNDNDAVREFGIEYASSQCQELLDKGAPGLHFYTLNQSEAILSILRNLNLE
>A0A2D7WSI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp|TrEMBL
MTLVNERQAFNRPDEEAAARFRDLVRSASIEATPRQILTTEHLPDLLPAGTCVYVPFLPK
GQFSDTLEASRRLLDLGMQPVPHVPARMAQSRGQLRDWLAQLDESGVDRLLLIAGDSDAV
AGPFPDTLAVLESGLLAQFRFHGIGVAAHPDGHPMADRATLAQALSVKREYARTTATRLW
VVTQFTFDAEVVIDWLQGLGNILEEVPVYIGMAGPTRVKTLIAYATMCGVGASARMLLRR
PGSARMLGAWKPDDMVRALVQYCLENPETLLRGIHLFPFGGLRQSAQWIREHSGSFENNR
EAVP
>A0A2G4GJR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVINHINQAKETLVSFEVLPPLKGKTINSLYQHLDPLMEFKPSFINVTYHRSEQIFKKK
VDGNFEKVEIRKRPGTVGICAAIMNHYKIDAVPHLICGGFTQRETEDALIDLNFLGIDNV
LVLRGDATKNETNFEPEANGNRYAIDLLKQVDSLNNGIYLEEDIRDGFRTHFCIGVAGYP
EKHFEAPNLESDLEYLKAKVEAGAEYIVTQMFFDNAKYFQFVEKCKENGITIPIIPGLKP
ITNKKQLTMIPKIFHVDIPSDLLNGINRAKSDEDCEMVGQEWLIHQSQELKKAGVPVLHY
YTLGKPRIIYNAVSKLF
>A0A316GEQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseicyclus mahoneyensis|TrEMBL
MTAPRVSFEFFPPKSLEASFRLWETLGVLSPLAPTFVSVTYGAGGTTRALTHDAVKTIHA
NYGVDVAAHLTCVDATREETLEIAQSYAAAGVTQLVALRGDPPKGAGRFTPHPDGFANSI
ELIEALAKTGKFHLRVGAYPDPHPEAGSVQDCVDYLKRKIDAGANSAITQFFFEAETFFR
FRDACASAGITAPIIPGILPINSWKGVRKFAEMCGTPIPGWLDEAFDKAARDGREQLLAT
ALATELCTDLIEGGVEDLHFYTLNAPDLTRDVCAALGVTPKVALSEVA
>A0A2I0W3L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dendrobium catenatum|TrEMBL
MKVIEKIREAVDGEGRTVFSFEFFPPKTEEGVENLFERMDRMVAHNPTFCDITWGAGGST
ADLTLEIANRMQNIVCESLLIVVFPSQFDPSSFSSFSSPSHYQLISVETMMHLTCTNMPV
EKIDHALDTIKNNGIQNVLALRGDPPHGQDKFVQVEGGFSCALDLVKHIRAKYGDYFGIT
VAGYPEAHPDMIQEGGATLEAYSNDLAYLKKKVDAGADLIITQLFYDTDIFLKFVSDCRQ
IGITCPIVPGIMPINNYKGFLRMTGFCKTKITSEITAALDPIKDNEEAVKAYGIHLGTEM
CKKILAHGIKTVHLYTLNMEKSALAILMNLGLIEESKVTRSLPWRPPANVFRAKEDVRPI
FWANRPKSYILRTSGWDQYPRGRWGDSQNPSYGALTDHQFMRPRTRDKKLQEEWAIPIKS
IEDVHERFMNYCLGKLRSSPWSDLDGLQPETKIIDEQLSQINLKGFLTINSQPAVNGVKS
GSPTVGWGGPGGYVYQKAYIEFFCSVEKLSQLVENCKALPSVTYIAVNKEGLRLSNVGPN
AVNAVTWGVFPAKEIIQPTVVDPASFMVWKDEAFEIWTRGWACLFPEADPSRALLEEVRV
YE
>A0A522SWW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTDHLTNAQDTVISFEILPPQKGKGIESIYNHLDPLMEFKPAFINVTYHRSEYIFKKK
RDGAFEKVEIRKRPGTVGICAAIMNHYKIDAVPHLICGGFSKEETENALIDLNFLGIDNV
LVLRGDAPKNETFFAAEPDGHHYAIELLNQVVNMNHGIYIEDDLTDGLKTNFCIGVAGYP
EKHFEAPNMETDLFYLKRKVEQGAEYITTQMFFDNDKFFAFEQCCRKNGITVPIIPGLKP
ITTKRQLTVLPHIFHIDIPTDLSKAIIASKNDDEVAKVGKEWMITQCRELKAHRVPALHF
YTMGKTHIIYEIVKNII
>A0A2M8LZD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces carminius|TrEMBL
MTTFSFEFFPPKTAAGERTLWQAIRRVETLRPDFVSVTYGAGGSSRDRTIEVTRRIAAET
TLRPVAHLTAVGHSAAELRQIIGAYADAGIRDVLVLRGDPPGDPRGPWVPHPDGFTHTYQ
LVELVRSLGNLTIGVAAFPERHPRSPDWDTDIRHFVAKCRAGADYAITQMFFHVEDYLRL
RDRVAAAGCDIPIVPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAARDDRAAGHRIGV
EYATAMAGRLLAEGAPGLHYITLNRSTAALDIHRNVISSRSIRVA
>A0A542GBD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SLBN-115|TrEMBL
MTPGQPRRPAAGPAATTAAAGTTGTAGTGVREPAPAPRHVPHPAVPHPLGPRLSAPRPAV
PPAGRSGGAGRPAVTFSFEFFPPKTAAGEGTLWKAIRRIEPLRPDFVSVTYGAGGSSRDR
TVAVTRRIAAETTLRPVAHLTAVGHPVAELRHIIGRYADAGIRDVLVLRGDPPGDPKGAW
TAHPQGFAYASELVELVRSLGDFRIGVAAFPERHPRSRDWDSDIRHFVAKCRAGADYAIT
QMFFHVEDYLRLRDRVAAAGCDIPIIPEIMPATDHRQIARFAELCDASFPEALAARLHAA
RENPADGHRIGVEYATAMAERLLAEGAPGLHYITLNKSTAALDIHRDVLRSTSARILQSC
>A0A357TG09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDIHTEKAAEGKPTISFEFFPFKTPEGEAAFFGKTLPVLMTARPDYASVTYGAGGS
TREKTFEIVEQIQNEFSLTTMAHLTCIKHTQAEINATLDEANNRGIRNILALRGDPPPGD
DWSQTEGGFEFASELVTHIRGRGDFGVAVAGFPEGHIDCGEGREVDWQHLVRKVGCGADM
VITQMFFENADYFQLADFLRGAGVEAPLFPGIIPVANARQIKKFSAMCGAKLPEAFAARL
DELGDDAEAVCEYGIEYATAQCRELLDRGAPGLHFYTLNKSKAVLQILGNLGLA
>R1GZE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas molluscorum 848|TrEMBL
MGFHSARQVEALNQSLADLSGDIGVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKDRTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGVDKPEMYATDLVALLKAEADFDISVAAYPEGHPEARSAQSDLLSLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNFQTLAKFAGFTNVKVPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKV
>A0A3M1E9M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRIRDALEHNRPTLSFEFFPPKDDIGFWDLYRTIASLKPLDPTYVSVTYGAGGSTRRKTI
DLVVRIKRDVGIEGMAHLTCVEATQEEIGKISDELTARGVENILALRGDPPAGQERFTPT
PGGFRYAAELVAFIRNRHPELCLGAACYPEGHPETPDLEKDLANLKRKVDAGVDFLITQL
FFDNDCFYRFRERAVAAGITVPIVAGIMPILSVRQVKKFTQMCGASIPEDLLRRIEAVED
DAEAVRHLGMYHATRQCLDLLEQEAAGIHFYTLNRSTATRAIYQLIKTHLPARVAD
>A0A3D4Y8R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coxiellaceae bacterium|TrEMBL
MISSPINLSFEFFPPQDVEGLEKLLSVAKKLSALNPEFFSVTYGAGGSTRDNTKQTVQAL
RDHFDVPVAPHLSCIGSTRETITRILDEYIEMGIKKIVALRGDLPSGMRNPGDFSYASDL
VTFIREHSGDHFEIKVAAYPEFHPESKSSSEDLSHFKGKIEAGAQAAITQFFFNTEAYLH
FVEDCRAMGVAVPIIAGIMPISNWERLMKFSRTCGMDLPIWLKSRMDALGTDEMARRNLS
IKLLSHLCRRLQQAGVTDFHFYTLNQSKLSLAICESLLRVQRDE
>A0A6N0DXE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloligella sp. GL2|TrEMBL
MLQQNHKKSRGLDIGDITVSFEFFPPKTEKMEQTLWNSIGMLAPLHPSFVSVTYGAGGST
RERTHATIARVLEETDLKPCAHLTCVGATREDLDAVIRDYWEIGVRHMVALRGDPPGGVG
APYEPTPGGYVNAADLTAGIKKIAPFEVFVAAYPEKHPQSPTVEADIDNLQAKIDAGADA
AITQFFFDNDVYYRYIDKVRARGIDIPITPGIIPIHNFKQVSNFAMRSGTSVPDWLGHRF
EGLEDHPTTHNLVAAAVAAEQVLDLVDHGITEFHFYTLNRADLVYAVCHLLGLRPTVQAE
AKEGAAL
>G0I0B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-1755)|TrEMBL
MALGTRAVSDSQGVRTLLTSARFELMPFESFDEEITHLPDNATIAITTSPQLGIEKTVEK
TEEAAEMGYDVVPHIAARYVEDQEQLEAIAERLEQAGITDIFVPGGDREEPAGEYESAHG
LLEALAETEYSFEEVGITGYPEGHDFIDDETLAESMAQKEPYATYIVTQLCYDPETVVEW
VEDIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDDEYNIRGVHIYTFNQTPDTEKWRHNRLDS
>A0A4V7TLZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus amyloliquefaciens|TrEMBL
MGLLQDLEERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIVQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIAGLGADITGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAIQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTDKEVKIRREEEVI
SVRDERTEPGLDEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMAQAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A0F5I4S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Quasibacillus thermotolerans|TrEMBL
MTLLERLQSEVLIADGAIGTLLYSYGVDFCYEELNTTNPELIEKIHREYIHAGADIIQTN
TYGANAVKLARYGMEGRVQELNKAAVQIAKRAASPEKRFVLGTIGGIRGIQKSSIPLSEI
EAAVREQAEALLSEKPDGLLLETYYDLEELEKVLAVIRPMTELPIIAQVSMHEPGVLQNG
LPLNEALKQLESLGADIVGVNCRLGPYHTIQAFEEVKLPENAFLSAYPNASLLDVQDGRI
VYESEADYFGRAAVQLREEGVRLIGGCCGTTPKHIRAAKKALSGLAPVREKEVKKKKPVI
IQEAAPSPVAPLYEQVKKDRTIIVELDTPKHLDTAAYIKGAKALQDTGIAAVTMADNSLA
SPRVSNLAMGSLLKSEHNVRSLIHITCRDRNLIGLQSHLMGLHTLGLHEVLAITGDPTKV
GDFPGAASVYDVSSMELIQLIKQMNEGISFSGKPLKQKTNFSVAAAFNPNVRVIDRAVKR
LEKKIEFGADYFITQPVFTKEKIVEVYEATKHLPTPIFLGIMPLTSSRNAEFLHHEVPGI
KLSDETLARMKTHENDKEAAAQEGLKIAKELIDTAAGLFNGIYLITPFLRYEMSIELIRY
IEEQDRKLNERGIAHVQTTSN
>A0A524F2U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MGEKKIYSKLGEVIAKGDFVLTGELEPEKTCDLSHTIQEAKEMAPYVVAANVTDSPLGIV
TINSMAVSHIIQKETGLECVWQLTVRDVNKLGIAGMIMGGHALGLRNILSLTGDHPNMGD
MPESKPVFDLDSATLIKLVREMVDKGSINGHEIEHPPTLHVGGAANPNADPMEAEILKIG
RKAEAGAEFIQTQVVYDIDRTIEFLKGIQKYKVPVMLGIFPMKSYGMAKGFDMFVPGVDV
PKDILAKWKSVKTDITDKKEQKNVYDQLNYEFFKPFISELKSKNLLAGVHCMAVHYTRIF
PKLVEVIGA
>A0A7K4CZV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MVKQVFSNLKKALVEGKFVFTGELEPHFSTSIDDTIEDANAMKNYVTAANVTDNPASDTG
FVSNVASHIVQKETGLEIIWQLRCTDKNRMALIADLLAAPRLGLKNVLALTGDHPWCSPH
WRPSKPVYDLDSTTLIRLVNEMVEKHTAFGKEYAGPPVQLNVGGAANPNAGPLEAELAKL
QRKAKVGCDWFQTQVVFDVQKTLDFLKEVNKTGVPVLIGLFPIKSYEVANGFNTMVPGVK
VPDELMAKFKEIKTQWKNVDKKRMEEEYLKLNVDYLGPFIQEIRNKKACAGIHIMAVHYP
QSFAPLFKYVQ
>A0A6G6SMU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus vulgaris|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTEEMENILWQSLARLNTLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASREELQHIAQDYWQSGIRHIVALRGD
LPDNTQKPEMYATDLVHLLKGVGNFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMNKMFD
GLENDPETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPELVRA
>A0A1V3HC00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinivibrio sp. MA351|TrEMBL
MSYTHAGHIDALNQNIADLDGDINVSFEFFPPSTPSMEETLWNSVHRLKGLKPKFMSVTY
GANSGERDRTHDIVKSIHDQTGVAAAPHLTCIDATEDELRHIARDYWQNGIRDIVALRGD
LPSPEKKPTMYAADLVRLLKEEHDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAQMTHVRVPQWMHKQYQ
GLEDDPVTRQMVGASIAIDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPLAVAP
>A0A0P9HY30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cannabina pv. alisalensis (strain ATCC BAA-566 / CFBP 6866 / ICMP 15200 / BS91)|TrEMBL
MATYNPDFFSCTYGAGGSTRDRTLNTVLQLENEVKVPAAPHLSCVGDSKDDLRSLLAQYK
AAGIKRIVALRGDLPSGMGMASGELRHANDLVNFIREETGSHFHIEVAAYPEMHPQARNF
EDDLKHFVNKANAGADSAITQYFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLAR
FSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQADP
SLAVWNNLQLPR
>X8DRF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus subsp. bolletii 1513|TrEMBL
MTTNPLDRDGPVAELQDPGSIADRLTAVQPGEIAFSVEFMPPRDEAAEARLWRAARVFER
YRPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEERLLRAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTARG
>A0A1Q7QRH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_1_40CM_2_66_13|TrEMBL
MKPLRAQGRTLAELLRAPRYEVLPTDNAAELVAAYVPREVTITVTASPRRGMPRTIHLAV
ALAKLGYHAVPHLSARLIHDRVELGQILVALKDAGIKNVFVVAGDAREPAGLFPDALSLL
AALPPDHGLTEIGVTGYPESHPFIHDDMTIQAMWDKRRLATYIVSNMSFDPEGVKRWVGR
VRNRGVELPIYIGMAGVADPARLMRLSTKIGLADSARFLRGHPSWVARMFRPGGYEPGRF
VNALLPDVAMPERRIAGLHVFTFNEIEPTERWRREMLAEIR
>A0A1V8U429|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rachicladosporium sp. CCFEE 5018|TrEMBL
MSRPAPTVPPNMADDRITTKLAALPRDATYFSLEFFPPKTSQGFSNLHARLARMAHSLRP
LFVNVTWGAGGSTSAKSLALAELTQRSLGLTTCLHLTCTNMSRKLIDEALEQAKVLGVRN
ILALRGDPPRSDEYRAEGAAVGEDEDDSNLEFTWAVDLVRYIKKTYGDYFCVGVAGYPEG
HADTSHPEHQGVGLDLPYLVEKTSAGADFIMTQLFYDVDAFLKYENTLREHESGIFKEIP
IIPGLMPVQSYQILRRTTKLSHAKIPLNVLKRFEAVKSDDEAVKRVGVDVLSEFVDKIKA
RPDVRPRGFHFYTLNLEKAVAHILERSSLIPPYTPTIIEKNGFTSPEGAIAEDESSTSPP
TNGHATRTRRESSTANSAPRNRVVVSRTRASSTSSTRTSAFEAPEDEAGVPRDKINSRAN
TLAISEGEGALGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHVSIAEATRLWGHPSST
ADLSEIFRRHLEGEVDAVPWSEEGLSPETLTIKSQLLALVQKGWWTVASQPAVNGVRSTD
PIFGWGPRNGFVFQKPFVEFFLPAQDWKRLQPILDEDPRITYFASDAAGDSAASDEESVN
PVTWGCFTGKEIVTPTIIEGVSFRAWCEEAFGIWSEWRGVYGKGSPSSKVLDQVRKEYWL
VKIIHHGYLEPEALWETLVKA
>A0A4R0YHE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseococcus sp. SYP-B2431|TrEMBL
MDASPPNTLERWLTGPRVGTLPSPSSLPAPKLSFEFFPPKNEKLEADLWTCIRRLEPLAP
RFVSVTYGAGGSTRSRTHDTVSRLVRETSLTPAAHLTCVGATREEVDEVARAYWAAGVRH
IVALRGDPPAGASTYEPHPGGYAQAEDLVRGLRRIGDFDISVGAYPEIHPAALSADSDLD
FLKRKIDAGATRAVTQYFFDTDVYLRFLDRCHAAGITAPIVPGIMPVTNFASVKRFSAMC
GASVPDWLARLFEGLDEDVDTRRLVAATLAAEQVRILQANGVDEFHFYTLNRPDLTYAIA
HILGARPAIAAA
>A0A417MIF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. TF11-2AC|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A0Q6VYH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. Root351|TrEMBL
METPNFSIEFFPPKTAEGAEKLRAVRAQLSELHPKYFSVTFGAGGTTQTGTLDTVREILA
AGEDAAPHLSCVGGTRESIRAILNEYKSHGIKRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQAKSPQDDLLAFERKVKAGANAAITQYFYNADAYFQFVE
QAQKLGIAVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSAAIKAFGLDV
VGSLCERLLAGGAPGLHFYSMNQAAATTALWQRLV
>A0A4Q5P4B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MNLPISFEFFPPKTPEGAQKLRATRQALYAEKPEFCSVTFGAGGSTQEGTFATVQEILAE
GVSAASHFSCVGATRATVRAQLGTLRSMGVKRLVALRGDLPSGYGAGGEFQYASDLVEFI
RAETGDAFHIEVAAYPEIHPQAKSADADLQAFATKMKAGADSAITQYFFNADSYFRFVED
AEALGVTAPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVI
SGLCEQLYAGGVPGIHFYTMNQAPATLELIRRLRASDTAGRD
>A0A0Q6CH95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas sp. Leaf427|TrEMBL
MARRAPSSGKDIRVSFEFFPPKSDKMEETLWAAIERLAPLSPSFVSVTYGAGGSTRERTH
HTVSRILKETDLAPAAHLTCVDASREEVDAVVRQYRDTGVRHFVALRGDSQAGAGAAYVA
HPGGYRNAVELAAGLRAIDDFEISVSAYPEKHPESADFATDIDLLKRKVDNGATRAITQF
FFDNDLYERYVERVRKAGIYIPIVPGIVPIHDFVKVARFSAATGATIPTWLAERFEGLEN
DAQTRSHVAAAVCAEQVLDLVERGVDDFHFYTMNRADLVYSICHILGLRPKTGEPAASVA
GAGTAAAA
>A0A497DQ25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MSLFTPGRRWQPPFFPFKKEPFGKRVLRSIERWTKGPMFGCRMCGNCLLQETAFICPMEC
PKGMRNGPCGGSTPEKCYVDETRPCIWYKIYERSFKMGREHMLLEVLPPLDWDKVGTETW
GDVARSVRKYGTGSFIRKRFSDNKEKKQQSWEAVFQPVRQPHWWAGDSLYHAPAYDLPFS
RLEKELKSGKFVITAEVSPPLSTATGKLKRDITMVKELVAAVNFTDSASASPRMSSMACS
KIAAELGADPVLQIAARDKTRSGLQSDITGANVMGVHNVLCITGDNARIGPTPTSNTNIL
DMDAVQMLWILRRMRDEGIYLDGRKMKSPPRLFLGAAASPFASEQRFQALREEKKINAGA
QFFQTNLIYDPEGLDLWLEALDKRNILDKVYILAGVTPIRSKRMAQYLHHNIPGVRVPQP
ILDRFDEAKEDDYEELGVEIALEIIEKIKDKQGINGLHLMSVGWEAIVPRILSDAGLSQF
QGNQ
>A0A8C6KZ42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius furzeri|TrEMBL
MVNQVQRVDGSWLSCKSDSSGTSNSGGESSKESSRCSTPVLDAVRSDRLRDKMRRRMESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEEEEGGFNHAV
DLVKHIRSEFDDYFDVCVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTF
LTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKREESVFEVFTCYITGQLNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDAVVGWGPAGGYVFQKVGTRFVWSFLMKACLCVSSVSSVVSL
CVQQAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAHEMQPNAVTWGIFPG
REIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDF
PLKSCLWQVLDDMFELLDAPLETLADGMPGDGSHGDGSHDNGTLAE
>A0A7G2S973|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp|TrEMBL
MSKRTPISFEFFPPKTDAGAEKLRTVHQELQRLNPEFFSITYGAGGSTRERTLAAINDFN
GQGTPVAPHLSCIGDSKLRIAELLDLYKRQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFQIEVAAYPEMHPQAENFDADIKRFIEKVNAGANAAITQFFFNPDSYFYFV
ERIQKEGIHIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDTQSIKAFGHE
VILKLCERLIDGGAPSLHFYSMNNTEPTRQLVIDLGLN
>A0A7C4WZR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MTVAEKLRTTKKTLFSFELLPPLKGRSIEDIYKAIDPLIEFEPLNINITYHQRETVYYPL
PDGTLEKRVVRKRPGNVALSAAIRFRYNVTVVPHVICGGHTKDDIEDLLIDFHFLEIHNL
LLLRGDAPKGQKIFVPEKNGHAHTVDLVRQVMDMNAGRYLDTNLKDPQPTCFSVGVAGYP
EKHIEAPNMETDLRYLKEKVDAGAEYIVTQLFFDNQKFFSFVEQCRAIGIQVPIVPGIKP
LATINDIKLVPQIFSCDIPQDFYRELEKCQTNQQVKEVGIEWAIQQGKELMAFGVPAIHF
YTYGISDNVKRIAKALF
>A0A8C6L097|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius furzeri|TrEMBL
MVNQVQRVDGSWLSCKSDSSGTSNSGGESSKESSRCSTPVLDAVRSDRLRDKMRRRMESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEEEEGGFNHAV
DLVKHIRSEFDDYFDVCVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTF
LTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKREESVFEVFTCYITGQLNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDAVVGWGPAGGYVFQKVGTRFVWSFLMKACLCVSSVSSVVSL
CVQQAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHVSQNDQLPVHRCARRGFDSSLG
IVSGTKPDQRPRDAAQRRDLGHLPGQGDRPAHRGGPGQLHVLEGRGLRLVDRAVGQALRR
RVAVQDDHQVHPR
>N9K8V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 284|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRIVHQELQRLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A2W5MNW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium zucineum|TrEMBL
MPATAPSRLPIPVSLEFFPPKTDEQRETLEKALPALKALNPEYV
>A0A1S1RGN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. BMG5.36|TrEMBL
MRDFLDAGEISYSFEFFPPKTADGERALWRALREIEALHPSFVSVTYGAGGSTRDGTIRV
TEQIATDTTLTPIGHLTAVNHSVAELRQVIGNYAGAGVCNVMALRGDPPGNPQGEWVAHP
EGLRYSSELVELVKSLGDFCVGVAAFPDKHPRSPDLESDADFLVGKFNAGADYAITQFFF
GADNYFRLVERVRARGCEAPIIPGIMPVTNVAQIERMALLSGADLPTDLVTRLRAAADDP
AAVRAIGIEVAVDLSERLLAGGAPGLHFITLNRSSATREVCQTVRARR
>A0A1S1SM76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. BMG5.36|TrEMBL
MTSLPVEQAGRLTALLHDVSLEMTGKDIEELELARESIPTGTRINVTFLGNEDLRMRLLA
ASAVKACGFVPVPHISARRLESRASLEVFLAALQADGTGEHVFVVGGDPSTPHGPYADAL
SVIQSGLLEQYGVRRASVAGYPEGHPDIPDQVLWPALQDKHASLTERGLAGDVITQFGFD
VDSVLAWVSALRERGVDAPVRIGVPGPAGVRRLLRYAARFGVGTSTSIAKKYGLSLTNLM
GTAGPDHFLRTLATDYDPRRHGEVKLHFYTFGGLRTTSEWIDHLRKED
>A0A523GVV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTQHIEKANGNTLFTLEILPPLKGQTITSIFNTIDPLMEFNPPFIDVTYHREEYVYKE
LENGLLQKQVVRKRPGTVGICAAIQNKYNVDAIPHILCGGFTKEDTENFLIDIGFLGIDN
VMALRGDAVKSETYFTPEKDGHNYANELVSQISDLNKGIYLDDEIQNQAKTDFCIGVAGY
PEKHMEAPSMDSDIYFLKKKIKKGATYIVTQMFFDNEKYFAFVNKCRAEGITVPIIPGLK
PLATKKQLNLIPHRFSAELPDDLIMEVVKCKNNEAVREVGVEWCVNQCKGLIVAGVPTLH
FYSMGKSDNIKAIAAQVF
>A0A436FN67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.10.1.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A1X1EBS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mixta gaviniae|TrEMBL
MSFFHANQREALNQSLAELNGRINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDASRDELRTIAQDYWNNGIRHIVALRGD
LPAGGGKPDMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPGWMNSMFA
GLDEDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPATALVA
>A0A2T2VLV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKITDILSNAKGCEFTFEILPPLKGQKAQEIFDHIDPLMEFKPPFIDVTYHREETVYKRL
PNGLLQEKVVRKRPGTVGICAALMHRYQTEAVPHVLCGGFTKEDTENVLIDLNFLGIENV
VALRGDQAKGESYFTPKPDGNKYAIDLVKQINDLNQGNYLDEELENTMATDFCIGVAGYP
EKHFQAPSLNIDIENLKDKVNAGADYIVTQLFFDNSKFFAFVDKCREAGITVPIVPGLKP
LVTKRQLSILPQIFHVDIPDSLAIEVLKCKDNAEVRRVGIDWCIQQSKELMTAGVPVLHY
YSMGKSRNIYEIAREIF
>A0A2D5UJQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MEKTVIQHIEESKQTLFSFELLPPLKGHDFESTQQAIDPLLEFNPSFINITYHQQEVVYE
DAGNGLMRKQTIRKRPGTVGISAAIKYRYGINVVPHIICGGFSKEDTENALIDLQFLGVN
NLLVVRGDPQPGTKVFMPEPDGNEHAIDLIEQIVNLNNGKYLDEKLKNTRSMDFCIGVAG
YPEKHGESPNMDSDLYFLKKKIQAGASYIVTQMCYDNQKYFNFVKLCREKGINVPIIPGL
KPIAIKENLINIPKSFSVDLPVDLVKEVLKCKNNKEIRQVGVEWAIQQSKELLDFGVPVL
HYYTFGQSDNIQKIAKAVF
>A0A351C6L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
PPFVDVTSHSAQVYYEEQQDGSWRRHIKRKRPGTLGLCAAIQGKFGIQTVPHLLCKGFTR
EESEDALIELNYLGIQNVMALRGDDSGYAKPIAHDRTRNEYAVDLVKQIDDMNKGHYLEQ
LIDAAPTDFCVGVAGYPEKHFEAPNITWDVLNLKNKVDAGAGYITSQMFFDNDAFLGFET
RCREVGITVPIIPGLKILTSKRQLKTLPSRFHLHIPEALAAEIESARDEDVPEIGIRWAL
KQCQDLLDKGHNNLHFYIIQTPQHVSRVVSSLRKLA
>A0A0U4CZF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus actinosclerus|TrEMBL
MTRVSVELVPRSRSGLRAEIAEVAGALSGVDTVNVPDLTRYSLRSWVGCGFARPGFAAIP
HLRAVDFNPREPLPFLPLLEEHGLREVLVVTGDAPIDMSAKVYDQDAVDLIRRLNRDAPH
LRVYAGLDPYRQSFVRERDYLERKLDAGASGFFTQPFFDRRLLDTWADLLPDGTDVWWGA
TSILTEASFNYWRARNHAVFPRTFTPTLDCNRAFARDLLTFAREREQHAYFMPVKVNVLE
YLGGIL
>A0A425Y5P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labilibaculum euxinus|TrEMBL
MKVIELLNQAIENKTTHFSFELLPPLRGNSIYKVFNTIDKLKEFDPKYINITAHRDEVVF
TESESGLIEKKITRKRPGTVAVAAAIKNEYKITVVPHVICSGFTPEETENALLDLNFLGI
YDLLLLRGDSSSRHAFISSEGEHKYAIDLINQVNEINKGGFLDGTHVEPFATPFSFGTAG
YPEKHEEAPNIDSDIYWLKKKVDAGAEYIVTQMFFDNQKFFDFVKKVRDAGITVPVVPGI
KPISALSQLTVLPQIFKTDIPEALAAEVRKCKTNDEVKQVGIEWGIQQGKELIQHGVPSL
HFYTLMASDCVRDIAKAIY
>B3E425|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichlorobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ)|TrEMBL
MKIADKLATGCRFVSVEYFPPKERQDWPAFFKVVERLASLNPLFASVTYGAGGSNQDATL
EIVTQMQQQLGLETMAHLTCVGAQAGRLNRFLDDLSKVGIQNILALRGDPPLETPVEQLT
ESPFHFASDLVSFVSQSHPQMGVAVAAYPETHPEAISPESDLGYLKLKMDLGGDFAVTQL
FFDNQLYFDFVKRARERGITKLIIPGILPVLNLKMIERIKQLSGAFIPPDFMAALEAADQ
RGGAAEVRKVGVAHARKQAEELLASGVQGVHLYTFNKAEAILELTEGLLP
>A0A317H5R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVIEHILQSKGTLVSFEILPPLKGKTINSIYDHLDPMMEFKPAFINVTYHRSETMFKKK
LDGTFEKVEVRKRPGTVGICAAIMNHYRIDAVPHLICGGFGKRETEDALIDLHFLGIDNV
LVLRGDAAKNESSFEPEPGGNQYAIDLLKQVANLNNGIYLEEDIKNGGKTNFCIGVAGYP
EKHFEAPNLTTDMQWLKAKVDAGAEYVTTQMFFDNKKYFDFVKLCREHGINVPIVPGLKP
ITNKKQLSMLPKVFHVDVPAELCNEIVKCKNDEDVELVGTKWLIEQSLELKKAGVPVLHY
YTLGKPKVICNVVREVV
>A0A2N0H7F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium kunmingense|TrEMBL
MNSLSEARRAAASPLFAGLEGDVGVSFEFFPPKTEKMAETLWDAIGTLSPLAPRFVSVTY
GAGGSTRERTHATVERIVRETAIPAAAHLTCVDASRAEIEEVARGYWDIGVRHIVALRGD
PPVAGTRFEARADGYASAADLVAGLKAVAPFEISVGAYPETHPEAASAAADLDNLKRKID
AGADRAITQFFFEPDTFFRFRDAAAAAGITAEIVPGIMPVTNFAAIQRMSGMTGTAVPDW
LAGLFEGLDDHPPARQLVAATVAAEMCRRLYAGGVREFHFYTLNRAELSYAICHLLGVRP
Q
>A0A853CUQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia shinshuensis|TrEMBL
MDCTDARFSFELYPPRNERAAAALPTTIDRLAAAGPDFISVTYGANGSSRESSLEVLRYI
LEHTDVSPMAHLTCVGSTHAEANRLIREFLDAGIRRFLAIRGDPPAGLAPGEDGLGDLKS
SAELVQLIHRVQAERVPYDALPVPGLHAEAVLSRREHVQIAVAAFPHGHPSSHSASQDID
ALLAKQAAGANLGISQLFFHAEDYLSFAQKAKDAGVLFPILPGIMPVTSPARLKRMLELS
GDDLPSDLAIQLEVEPDEEGRRQIGIDWTARLAERLLAGGAPGIHLYAFNQHAAVLSVLE
RAGLLHPASTTSATPQKAGDPA
>A0A6G1J4B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentithecium fluviatile CBS 122367|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTSMGFANLTSRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRSLIDDALEQAKVLGIRNILALRGDAPRSEE
YREEGQLPEEDSNKDFTWAIDLVRYIRKQHGNYFCIGVAAYPEGHSDESHPEHQDPKIDL
PYLVEKTAAGADFIMTQLFFDVEAYDGFEKMLREHESGVFKSIPIIPGMLPVQSYQILRR
VTKLSHARLPEDMLARLDAVKGDDELVKRVGVKVLSEVIEHIKKRPNPGPRGFHFYTLNL
EKSVSHILEDCHLIPQPLLDEDEDEAIDVTPAINLTPPEGALPTKERRRLSSVNSGPRNR
VIISKPSASKSSHPSYEAPETEAGLLQGPINTRANTLAISEGEGSLGREATWDDFPNGRW
GDARSAAFGEIDGYGPTLHVSTPQALKLWGHPVNRDDITNLFKRHIEGDLGALPWSEQGL
SPETQTISKELLALNSKGWWTVASQPAVNGVKSTDPVFGWGPRNGFVFQKPFVEFFIPSV
DWKALQPRLKAHEQITYFAGNAAGDFDASSEEGVNPVTWGTFAGKEIVTPTIIEAVSFRS
WCEEAWSIWREWQRIYPVKTETSKLLGGLRNDLWLVNVIWGDFVVGQGLWEFLMEG
>A0A829NDD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNJC398B00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A1H0ULE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litchfieldia salsa|TrEMBL
MGLLEELETKILIGDGAIGTLLHLHGIDSCFEELNLSKPDQIKFIHEAYIEAGANVIQTN
TYGANYQKLARYGLEDSVVEINKAAVTIAKEAAGNQAYVVGTIGGIRSFQKTTISLEEIQ
RSFEEQLTVLLDQGVDGILLETYYDFEELKTVLQIVKRETNKPIIANVSLHEVGVLQDGT
HLADAFSELENLGADVIGINCRLGPHHMIRSLEEVPLPKKAYLSVYPNASLPEYVEGRLV
YETHEDYFRESARLFRLEGVRLIGGCCGTSPKHIKAISEALRGLPPVTDKSVKNRQVEIT
TEVKIPNHTTPIHEIVKSRRSVIVELDPPKKLGVQKFIQGAKALHQAGVDSVTLADNSLA
SPRISNLACGSILKQQFNINPLIHITCRDRNLIGLQSHLMGLHTLGLNEVLAVTGDPSKI
GDFPGATSVYDVSSFDLISLIKQFNEGISYSGKSLGQKTNFSIAAAFNPNVRHLDKAVKR
LEKKIDCGADYFITQPLYNEKQIIDVYEHTKHLSAPIYIGIMPLTSARNANFIHHEIPGI
TLSQSIRERMENADQDPQKAQEEGIAIAKSLIDVAFDLFNGIYLITPFLRYEMTVELTNY
IKNKELAAIERKVH
>A0A8B2PQC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cepacia|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLMPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIDVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLVDAGVPGLHFYTLNTAAATRTICERLDV
>A0A7S2Z1R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloropicon laureae|TrEMBL
DHFGIGVAGYPEAHPDAICEDPEQFAKNYQEELVYLKKKIDAGGQMIVTQLFYDVGNFLK
FVKDCRNIGIECPILPGIMPIQSYGGFMRMTGFCKTKVPQEILDTLEPIKDNVDAVKAYG
IHLGTQMCKQLIDAGTPGLHMYSLNQDKAVLGILSGLGLISLEEPQKNPTPAIEEHKEED
KKATA
>A0A7T2FLH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. JNUCC-52|TrEMBL
MGLLEKLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQKPELIEKIHREYIAAGADVIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLEEI
LTTVEEQANVLLAGNPDGLLLETYYDFEELSATLKMLRAKTKLPIIAQVSMHEPGVLQNG
MALNYALHELEMLGADVVGVNCRLGPHHTIQAFEGVELPEKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVALVDQGVRLIGGCCGTTPKHIAAAKKYLEELTPIEEKLAKPEKVEI
VREAEPATYEPLLEKVKRERSVIVELDTPRHLEIDGFIQGAKKLYEAGADVVMMADNSLA
SPRISNVAMGALLKETHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKIIEIYEATKHLDAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSDDALSRMKACGEDKERSTLEGIAIAKELVEVAAEYFNGIYLITPFLRYDMTLELMKF
IEQLDEQKKGVSIDG
>A0A5N8WVW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces acidicola|TrEMBL
MPRPRPPRSTPSPLPASSSPAPTEGASDVTSVTDPRGSTPPLSRPVSRTAKAAVADALRD
ATYEILPFKSAEEKVLAHVPTDVALTVTTTEAKGIGPTIALAAALTEHGYRAAPHIAARL
VRDQAHLTDIVEQLRDSGIDRLFCVGGDAAEPAGDFPDALSLFQGLQTIGHSFTSVGIGG
YPEGHGLIDDELIEQALDAKAPYATQIITQLCFDAATTIRWARRVRARGVTLPIRVGIPG
AVSRQKLIRVSAGLGLGQSARFLKKQQNMFWRFFLPGGYSPNKLIEKLTPAFAQEDNNLQ
GFHVFTFNDLESTEAWRKAWLARLS
>A0A395RQU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sporotrichioides|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDAEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSVEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLERLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAVYPEWEATGLEAGGRAEAVNTRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGHPKTRQDINDLFVKHIQGELSAIPWSE
EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PANEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGSTEASPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRSSESEKLLNGIKDDYWLVNLIHHDY
VNRDALWEVLSS
>H6L959|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospira grandis (strain Lewin)|TrEMBL
MKVSEHFRQAEGQSLISFEILPPLKGGGIQGIFDTLDPLMEFKPPFIDVTYHREEFIYKR
RPSGYYEKTAIRKRPGTVGICAAIMNRYGVDAVPHLICGGFTADETENALIDLMFLGVDN
VLVLRGDPRKFETKFMPEEGGHAYALDLVKQVQNMNEGHYLDSTLMDAQASSFCIGVAGY
PEKHFEAPNLDMDLHFLKQKVEAGADYIVTQMFFDNQKYFDFVDKCRAAGIDVPIVPGLK
PITKKYQLSAIPRHFFIDLPDDLAKAMMAAKDAEARRQVGIEWCVMQSKELKAAGVPCLH
YYTMGDVDTIKSIAEHVV
>A0A1H2UE85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kandleria vitulina|TrEMBL
MKIIDRLNQGKVTLSFEVFPNKYSKNFEAVANKAKEIARLHPEYMSVTYGAGGGTSQYTV
NIAKEIQEKEGVDVLAHLTCVSSTKEKVHEMLESFEANGIKNIMALRGDLPETEVPHDYE
HASELIKEIKEYNPEFCIGGACYPEGHPEAKNKDEDIYYLKKKVEAGCDFLTTQMFFDNS
IFYNFLYRAREAGIEVPIVAGIMPITRKEQVKRAIQLSGSSVPSRFFSMVDTFGDNEKAM
KQAGIIYASEQIIDLIANGVKHIHVYTMNNPDVAEGIMNNVSEILK
>A0A3S0RRA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella dinghuensis|TrEMBL
MPALSFEFFPPKTDEQRAQLDRTAKELKSLNPEYVSVTFGAGGSTLSYTSDTVARLHQQH
GLDVAPHISCMGGTRAEIAALLDSYREAGYRRIVALRGDLPSGMASPGDFRYASELVRFI
REHSGDHFHIEVAAYPEMHPQAEDVHADLRHFKTKIDAGADGAITQYFFNADAYFRFVED
ARRLGVKVPIVPGIMPISQYAQLKRFSDACGAEIPRWMSRRMQGYYDDVESIRSMGAEVV
AQLCRRLLEGGAPGLHFYTLNRVKATRAVLDQLS
>A0A2E8Z6D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp|TrEMBL
MDLGERISTRGSEFLLFALTPPRTTVSEERAQEIADVTQARLAPIGLDGLVLYDIDDESD
RNPRERPFPFVATLDPADFRRRHLADWPTPVVVYRAVGKYAEDELRGWLGEPDTGRDLTV
FVGASSRESRPATSLARAQALLSEVRPDLPLGGVAIPERHTRRGEEHLRLLAKQQAGCSF
FVTQVVYDVNAAKNLVSDYAYACRDEGLEPVPLVFTFSVCGSMRTLEFLGWLGIDVPRWI
QNDLRHAGDTLQASYEHALGAARELIAFCRRLGVPFGINVESVSIRLAEIEASVGLAREI
ATGLRR
>A0A5C6B7A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stieleria varia|TrEMBL
MNLSDLFQSGKNVISFELFPPKTDEGMERLLENVQRLNQFQPSFYTCTYGAGGSTQGKTL
EVVAKVRELTGLPVASHLTCVGLTTEQLQQYLAEAKAKGADMIVALRGDPPKGSDTFQAV
EGGLRYANELVELIQSAFPQQFGILVAGYPEVHQEAVDAQTDLDNLKRKVDAGADVVVTQ
LFYDNADFYRFRDHCVAAGISIPIVPGILPVTNFKQAQRIASMCKARIPDTMAQAMEQSD
DEQYQFQIGVDHARAQTVDLLENGVPGIHYYVLNKSDAAEKLLDGMSLGIES
>A0A2G6F097|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriia bacterium|TrEMBL
MKITDHILQNQGKTRFSFEILPPKKGETIQSVFDGIDPLMPFDPLYINVTYHRQDYKYIE
QPGGLLRKVAVSHRPGTVGICAAINNHYEVDAVPHILSGGFTKEETEVHLIDIHFLGLDN
VMALRGDAKASEVYFKPEKGGHAYASELVEQISNLNKGQYLYEETEGHAKTNFCIGVAGY
PEKHVEAPSLDADLRNLKRKVDNGADYIITQMFFDNQKFFEFERKCREIGIDVPIIPGLK
PIVTTRQMTVIPQRFHLDLPEILVERLQAAKTKKEVEDVGVHWCIEQSQELMSNGVPILH
YYSMGKGRTIKRVADEVFGRKG
>A0A4U1LYP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia marina|TrEMBL
MTSRPILPDSPQTLPAENVSHIGHLERVLRSGQFAVTAELAPPDSADPQEVHARAQLFAN
HVDAMNATDGSGANCHMSSVAMCALLAREGYETVMQISCRDRNRIAIQGDVLGAAALGLR
NLLCLTGDGVQVGDHPEAKPVFDLDSLSLLEIVAGLRDKHAFASGRSLTSAPKVFLGAAA
NPFAPPFAFRPHRLAKKIAAGAQFIQTQYCFDLPRFQDFMHRARDLGLLEKCFILPGVGP
LASARTADWMRRHVPGVHIPDDVIKRLKSAKDQKAEGRDLCIEMIQQLREIEGVSGVHIM
AHRQEALVPEIIQRAGILQGRSTPPSSPVSNDSYAW
>A0A2E1SQU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MATQPHISFEFFAAKTEQGREKLHLTCEKLNRYNPEFYSVTYGAGGSTRDTTKQLVLDLQ
QQGYQAAPHLSFGGDSQETVLGLINEYQQAGISNLVALRGDLPSGIGGTTQXVHANELVA
LIREKTGDHFDINVAAYPEIHPEAESYSKDIYWLGEKFKAGANRAITQYFYNPDAYFKFV
ENCQKAGIDKPIVPGIMPLTNFQNLLRFSENCGAEIPRWLQWQLKERKDNKQDLIAYGVE
IVSQLCEALLAGGAPGLHFYTMNQWQISDSLCQNLGLDSSN
>A0A2A5GJU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MTNHHLSFEFFPPKTPEGREKLRKTHSQLSKFQPEFFSVTYGAGGSTREFTRDIVFEIQN
AGSSASPHLSIGGDSHESVLELLQSYKDAGINRIVTLRGDLPSGMGGAGQLVYANELVGF
IREHFGDTFELLVAAYPEIHPEAESYEKDIYWLRKKFEAGASRAITQYFYNADSYFYYLD
QCRKIGIEQPIIPGIMPIINYQNLIRFSDSCGADIPRWIRQRLQQYGNDTESVKAFGLEV
VTNLCEKLLAGGAPGLHFYTMNQVEANAALCRNLGFSEGL
>E9FP75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. M334|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQGLAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAESIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDIPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A7K2I5C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID6137|TrEMBL
MALGTASTRTDRARTVRDMLAGGKTTYSFEFSAPKTPKGERNLWTALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVAHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVEAGCDTPVIPEILPVTSVRMLERLPKLSNAQF
PDALKERILAAKDDPAAVRSIGIDFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHHPPQA
>A0A6B1STG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A7C4LF71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MREQDGYKSGSNLERVLKQGHFAVTAELGPPKNADADVIRRKAALLRGVADAANITDNQT
AIVRMSSIGAAVIALQAGLEPVVQMTCRDRNRLALQSDLLGAYALGLRNVLCLTGDHQTF
GNHPQAKNVHDLDSVQLVQMVAGLRDPGCFQCGEAIQGVNPRFFIGAAENPFGDPFEFRP
LRLAKKARAGADFIQTQMIYNVPKFREFMQRVVDLGVHEQVFILAGVGPLKTPAAARYMR
DQVPGMEVPDEIVERMEAAGRGLEDKKARSAAYREAGLQICIEIIQQIRAIPGVAGVHLM
AIEWEEAVRPIAAGAGLLPRPAVGQPATTAQEAGHG
>A0A661VJ80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MDADDYVAISREDRSSIAQLLEPARLRERLNISLREKLNTLKEAILSPDVFCVTWEQIAG
RGALEMQQEQIIENAAKAAKSGKIHGISVTDNPGGNPAISTEMLCAEIKKLGIEPLVHLA
CRDKNRNEIESMLYGLAAEGVRNLLVLTGDYPSSNGFNGRPKPVFDLDPIHVLQLIQRMN
KGLEHELMGRKRILTPTDFFAGVCVSPFKKLEAELMGQYYKLSKKIEAGANFIITQVGYD
ARKFHELLLWLRAHGYNIPVLANIYILPYGTAKLMNANKIPGCVVTDKLLAELANEAKGE
DKGKSARLLRAAKMYALAKGMGFAGAHIGGHGITFEMVEYIIEKGEELSKNWQDLVAEFD
YPQKDGFYFFEWDPRTGLNLDKPAARPSELPASAVKALKPSMYGFCRIAHALLFRPESLL
FKALRPFASFVDSSPILRRIFGYLEHLIKVALFGCMNCGDCALFDVAYLCPMSQCPKNQR
NGPCGGSYEGWCEVYPNERKCIWVRAYERLKAYKEEDRIGAYIVPPCNWELWETSSWLNF
YLGRDHTAKRLGVKPPPRVGFFRDG
>A0A7C2XEG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPLFTPARRWQLPYLPFKRDSFCQRLLVAVERAVKGPLFGCRMCGNCMLQETAFICSMEC
PKGIRNGPCGGSTPARCYVDETRPCIWYKIYERAFNMGREEKLLEVLPPLDWGKVGGETW
GDVLHQIRRVGPGRFVSGLLSRDPVQRTQVWDSVFKTVRQPDWWEGDAEYHPPAYSEPIS
ELERRLRAGEFVVTGEVAPPLTTSTKKLVSNIELVKPYLTAINFTDCPAATPRMSSLACS
AIAVQNGAEAVMQIAARDRTRVGLQAEVIGASALGIRNVLCLSGDSMRMAPDPCGRMDVV
DIDSIQMLWILRRMRDDGKYLDGRSIKFPPNIFIGAAASPFASQPRYQAIREQKKVNAGA
QFFQTNLVFDPQGLENWLNELEKRNILGKVYILVGITPLKSWKVAQYMHHEVPGVFIPEK
IMKRMENAGDGAAEEGVTISLELIESIRKLQGVQGIHLMAVGWEEIVPRIVTEAGLLPED
FVAPEMISP
>A0A1F5YDT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Glassbacteria bacterium GWA2_58_10|TrEMBL
MSLPAFKDALRDSILVCDGAMGTQIYSHGVHLSRSFDEVNLSNPYLVSKIHHDYISAGAR
VIETNTFGANRLKLRRHALADKIGEIIAAGVKLAREAAPRDEVYVAGSAGPLGVKLNHPE
GIEKDEAREVFAEHFTLLLDNGVDLLFLETFSDPLELALALETARGLRPDFPVVASAVFD
ERGLSQGKTPEQVVGLLEPFQPTAVGLNCRLSADLMLPILQRMHAATRLPLSAMSDAGES
RLVEDRDMYISTPEFVADYARRAIQGAGVRLVGGCCGTNPRHIRAIAATVRMLQPGTPSI
SVKEAEAGPPRFEKEGKPWKEKTPFAAKLARGKFVSSVEIRPPRGLDSSSVKEALEGLAA
AGVDAMNIPDGPRATARMNPIHIASRLNTEPERIEIIVHYTCRDRNLLGIQADLLGAYSL
GLRNILAVTGDPPKLGDYPDATAVFDVDAIGLVGILNRLNHGEDLAARPIGDQTEFLIGV
GVNPGAINLDLEVERLMAKIENGAEYVFTQPVFDPEFLTRFLDRAGKLPVPLLAGCYPLY
SYKNAEFLHNEVPGMTIPEEVRLRMKEAGTGARAQDMGVEIAREALREVRQRVQGAYIMP
PFDKWELAVRVLDGIIEPAPVSKK
>A0A7V6EC34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
KQIKRILSLCGASMPPEILIMLDKYENNPDDLKKAGVEYAIKQINDLLDNDVDGIHLEPM
NKPELAADILKDLRHRFC
>A0A2E7Z5Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLEDSDRFLTAVEIETSRGLLMAEASRKTAELAKTLSEFDRVDFVSLTDNPGGNPHIRPE
VLGQDLLFRGRDVVINMSCKDYNRNGVESRLWALGSQGFSNVLALSGDYPIGGFQGQAQP
VFDIDSVGLLELMRQMNEGLSNQMWGSVDREDRLEKTNFFAGCAVSPFKKLEGELMTQYF
KLALKVRTGANFAITQIGYDSRKASELFQYVKTNNIDVPLIGSVFILTAPAGRFFNRWGV
PGVWVSDALRDEGNRQAKSKDRGRAFFSELAAKQIAILKGIGYRGAYISGRPQLKRIQSI
LCMAESFGENDWKDFAKEINFAQPGEFYHYGQGDNAGLSSNEVSKSYLVSKSKPKRAKSR
FTVPLQYRIGKVAHDLVLAEGAPGFNPARAIYGQLEKSKKLSGFAHMLEQASKVPVYHCR
DCGDCSLPDIAYLCPESQCVKSQRNGPCGGTKAGKCEILDQECIWIRAYDRLKPFGDETK
MLQRPVVFRDASLRHTSAWANTFLARDHHARQKAVDTDGGA
>A0A2W4P0Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKTPFLERLAAPDPLLADGAMGTMLYARGVPLDACFDHLNLTRPELVREIHEAYVRAGAE
LLETNTFAANRFKLQEWGLEDEVRAINMAAVRLAREAAATAGREVYVAGSIGPLGVGIQP
YGRTRREDAREAFAEQILALAEAGVDLLLMETFTALAEAEEALAAAREVAPHLPVVTQMT
FAPDDHTLLGDLPGNVARALHEAGADVIGVNCSGGPEQISRVLQAMRQAVPEARCSAMPN
AGFPQIVGGRTLYTATEGYFADYALTFKAMGARIIGGCCGTTPAHIAAMRAALDDPSRPL
PQIHVFEPAHEVDSASPERPTEMARRLAEGKFIISVEMKPPRSYSLNRLLASAQLLQDAG
ADVVNVADSPTARMRMSPWAVCHLLQSRLGMETVLHFPTRGRNLLRIQGDLLGAHALGLR
NIFVCMGDPTRIGDYPNAMDQYDIVPTGLIRLIQQRLNQGVDQAGNSIGQPTTFNVGCAL
NMGAANLDKEIELLRKKIDAGANFALGQAVFDPRVVERFHRRYEELMAEPLRLPVLMAIM
PLYSFKHALFLHNEVPGIHIPETILARIEAADDPPQEGVRIAQELLRDMKDMVQGAYIIP
AFGYYNLAAQVMDVVATPGA
>A0A359HEF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPVFTPGRRWQPPYLPFKKEPMGRRMLAATERMIKGPLFGCRMCGNCLLQETAFICPMEC
PKGARNGPCGGSTEEFCYVDNTRPCIWYKIYERSFKMGREEMLLEVLPPLDWDKTGTETW
GDVVRQVKKVGTGTVAKGMLTRDAASRTATWDSVFRPVRQPEWWEGDSQYHAPAYDEPVS
ELERRLKAGEFVVTSEVAPPMSTATGALCRNTDNIKPYVAAVNFTDCPSATPRMSSIACS
KIALDRGAEPVLQIAARDRTRTGLQAEVIGAYSLGIRNILCLSGDNARMGPSPIGRSDII
DIDSIQMLWILRRMRDEGKYXLPLPLNPNSRPSASTKKSTPGRNSSRPTWFTMPMAWKSG
SMS
>A0A535NI46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MIAGPPAKPSRLRLDSASREALRRFLSHPRYEVLPSEEAGDLVLRNVPTEVTITVTSSPR
RGIEATLALAEKLAAGGYAVVPHLAARLVRDESHLKEILARLDAIGGRVFVVAGDSQEAA
GEFPDSISLLDAIAGHAPAMKEIGVTGYPERHGFIDDDLTIQAMWDKRRQATYIVSNLCF
DVRVVKNWVARVRKRRVPLPIFIGMAGVADPAKLLRVSTRIGIADSARFLRGHTNWLMRM
IQPGGYAPERFATGLMPELARPDMKVAGIHVFTFNEIEPTEQWRQQMLARLR
>A0A2E1ZWV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKNISKILSXQRTISFEFFAPKEXAXXEQLLQSIKEINXXKLSFISVTYSVKKNSGPTDL
XVEKISXETFIPVMPHLTCITHSKNEIDAIIEQYQKKSISNILALRGDIPEAGHFSKKDF
ENALELVRYLRNKTKLDISVAAHPEGHPDAIDAESDFLYQMQKIQASDFAITQFFFEPNY
YFDFIEKLYKQGNKKPVLPGIMPPTNSDALVRMAKXNGSHIPKSIIEKLSSLKDXKAKED
FAKEIVLDLXDKLISNXAPGIHLYTMNNVSXSEQILNEIEF
>G0CDC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. raphani 756C|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAAKLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAIDADSDLKYFKAKVDAGADAAITQYFYNADGYFHFRDA
AQRLGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDADAVRAFGAEVV
AALCERLIAGGVPALHFYTLNLAKPTTQVLQLLGR
>A0A4U0NLR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces piniterrae|TrEMBL
MALGTASTRTDRARTVRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNVIGQYADAGIRNMLALR
GDPPGDPMGEWVRHPEGVSYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVSDAGCATPIIPEIMPVTNVRQIERFAQLSNAAF
PPELADRILAVKDDPAAVRSIGIEYATELCARLMAEGVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A350ZPQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp|TrEMBL
AGGSTRERTHDTVRRIVAETSLRPAAHLTCVGATKAEVLAVAEDYWQAGVKHIVALRGDP
PAGMGAKFEPHPGGFLDSVDLIRGLREHRPELGKCFEISVSCYPELHPENKGWDAEIAFL
KAKQDAGADRAITQFFFEPDVYFEFLEKAHAGGVTLPIVPGIMLQPNFAGLKRMAAMVQA
SIPAWLDRLYDGLEEDDETRDMVTATGAAELCHKLHESGVRDFP
>A0A2D9A2U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVAFHLYGQRTSPTEKLHRRNKSAGGDWIPGLKIKDILTKTRPISFEFFPPRNAEGIPAV
LETMDELKPYCPDFVSVTYGAGGSTRAFTEEITLQIKRETGVEVMAHLTCVGQNKEEIHE
VLQRLESEGVENIIALRGDPPRGSTEFAPVEGGFQHATDLLKHVXSNFRFGVAAACYPEG
HTESVDLDTDLDYIKMKVDNGADFLVTQLFYDNRHYFDFLERAHAGGIDVPIIPGVLPVL
NSAQVRRFTALSGSEIPPDLDKLLDKYADSXNSARDMGVEYATAQVRELWDAGVPGXHFY
VLNRSYSVSRILDNLTISGHQRQD
>A0A2E6XGY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIIEILKKTRPISYEFSPPRTADGIPAVLEALDELKVYRPDFVSVTYGAGGSTRAFTEE
ITVQAKKVAGVEVMAHLTCVGQTKEEIHGVLERLDAAGVENVIALRGDPPRGETEFVPVA
GGFPHATDLLSHIKANFKFGVAAACYPEGHTESVDLDADLDYIKLKVEKGADFLVTQLFY
DNRYYFDFVERAKAAGIDVPIVPGVLPVLSSAQVRRFTTLCGSTIPSDLGKLLDKYADDD
SSARDMGVEYATAQVRELWDQGVPGVHFYVLNRSYSVSRILDNLALPGHQRED
>A0A1D2SS36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. SCN 65-20|TrEMBL
MNQYQLSRRSDIGDKIRVSFEFFPPKNDEMEARLWDTVTRLEPLKPQFVSVTYGAGGTTR
ERTARTVKRILDETTLTPAAHMTCVDAEREQVDQVISEFAAMGVTRFVALRGDPAEGVGA
AYRPHPGGYANGAELVGALKAQGDFDISVSAYPEKHPESPDFVTDFDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARKAGIYIPIVPGVLPIHSFAQVANFSARCGAHVPKWLAERFE
GLDKDPQTHALVASAVAVEQVLDLVERGVNDFHFYTMNRADLVFAVCHMIGIRPRENVPG
SAAA
>A0A2E4QJL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLNTLEIIPKQYERIFSLPKNMFGDIYVASIPGDPVDNIISSCKKLVNKGFNVIPHLPAR
NIKDEKELEYYLFQLDKLNIKKILAIGGSSTEKDPTFSSTYEIFKTGIFENFDFDQINIA
GHPEGNPFDEKSDENLKEKLNWLVNKDYKCNIVTQWTFDPKQTNIWLEKINKDISDISNN
TEIHIGIAGPAKFTTLLRYAKVCGVSASAIIAKNKGLGLTKLLKHNPKEIINSIVGYDNL
HFFPFGGINELVDWKKI
>A0A4P5V734|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIHDILHTTHPVFSFEFFPPKTEEQQRQLLETIRRLGPLSPAYVSVTYGAGGSTRALTI
DTVNRLKEEFGIEAMAHLTCVGASRDEIRETLDTLASHGVENVMALRGDPPKGTKDFEPA
PDGFAHASDLIQFIHENYDFSIGGACYPEGHFEGNTGRRQDPDMDLEHLFKKVKAGAKFL
VTQLFYDNEAYFQFVERARMFGIEVPIIPGLMPVVNAESIPRIAKMSGASFPDSLMREVQ
VRASDPDAVVELAVAFTALQADELLRHGAPGIHFYTLNRSPATSAIVSALRLIRPWEVHN
>A0A535K162|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARIAELLAAGRTVSFEFFPPKDNEEQALLTRTIADLQPLKPSFVSVTYRGGRISRERTT
RVVIDLLRTTDLTPMPHLTCVAHPRFELGEIIGGFRAAGLENLLALGGDPLPAEESYKEL
EYAWELVELGRRLGFESIGVAAHPAGHPRSPDLKSDREHLAFKMRMADFAITQFFFKVEE
YERLRDEMAALGITKPIIAGIMPITSLVSVQRMAQLSGYAVPDDIVRRIEAGGDDRAEIR
KRGIDVATELCRQLLEAGVPGLHFYTLNFSKATREIHERLGFVMRR
>A0A1F7ZQ51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus bombycis|TrEMBL
MHIKEKLAQNETAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREQEK
WEAAEGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDIFISWVKKCRAKGINVPIIPGIMPIQTYSAFIRRANWTKIHIPEDWLETL
EPVKNDDAVVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIRDLSHLFVSYLEGKLSRLPWSDTPISSEAKTIKPNLIE
LNNRGILTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIESNE
DLTYHAVSKNGELRTNTQDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKFIQGLVDNWYLVNIVNNDFHNTYDLFELFKDLNVKDFDVEVTADNAGSK
SQAAEATAN
>A0A503IVJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-4-17|TrEMBL
MSDRQRDENPDGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHEDITETQVDMVK
TAH
>A0A535YZY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
QVGIDTLIHFTSRDKNLMALQAELIGAHALGIRNVIALTGDPPRIGDYPSATGVWDVDSI
GLIKILQRLNEGYDWLGTSIGKPANFTIACAVNPSAEDLDHEIDRFRQKIEAGAHLAMSQ
PLYDLETLERFFQKTGPLPIPFLLGVLPLQSSRHAEFMHNEVPGIVVPQQLRDRMRQAGE
NGIAEGLQQSRELLQDTTHLVQGVYLMPSFGRYEVVAELVRWLRQQPVTAGTRPR
>A0A844GB28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paludibacterium denitrificans|TrEMBL
MSEQKKTFSFEFFPPKTAEGMAKLRTTRQQLAQFHPQFFSVTFGVSGTTREGTLATVLEI
RNEGYAAAPHLSCIGSTRDNIRSILNEYRNHGIRHIVALRGDIPSGMVEAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQAKSAEDDLNNFVRKANASANSAITQYFFNADAYFRF
VDEVRARGVEIPIVPGIMPIVNFGQLCRFSDMCGAEVPRWLRQRMQSYYDDTASIRALGL
DVVTELCDRLLANGAPGLHFYTLNAAGLVSTVWQRLGL
>A0A7Z2GJJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia acidisoli|TrEMBL
MKPIELSFEFFPPKTPDGVEKLRATREQLATLDPKFVSVTFGAGGSTQQGTLDTVVDIQK
AGVDAAPHLSCIGSSKESLREILGQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQETGDAFHIEVAAYPEYHPQARSPRHDLEAFAQKVKAGANSAITQYFFNADAYFRFVD
EARKLGVDIPIVPGIMPITNYSQLMRFSEMCGAEVPRWIAKRLESFGDDRDSIRAFGLDV
VTDLCRRLVDAGVPGLHFYTLNTAAASKTICERLSA
>A0A7Y3IVB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium|TrEMBL
MTTRFSFEFFPPKTEAGAERLLQVHQQLVSLGPEYCSVTYGAGGSTRERTLNTVLAMSAS
SVPVAPHLSCIGDSRESLKQILGTYRQAGVHRLVALRGDLPSGQVGLGELPYAADLVAFI
RESYGQEFHIEVAAYPETHPQAENFEQDLRYFLAKVNAGADAAITQYFYNIDAYWHFCER
VRQAGCSIDIVPGIMPITQYSNLMRFSEACGAEIPRWLRKQLAAYADDQDSIRQLGEEVV
TRLCQRLLEQGVPSLHFYTMNQLEPCRNIVMNLGLQT
>A0A7J7T0Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pipistrellus kuhlii|TrEMBL
MDLPNPEVLPAGHCCPSLGTRALEAGIMRFSVPPSIRHSAMANEPRGNGGPNPRLEGSGG
GMESSKDSSRCSSPGLDPERHERLREKMRRRMESGDKWFSLEFFPPRTAQAAVNLISRFD
QMGAGGPLFIDVTWHPAGDPGSDKETSSMTIASTAVNYCGLETMLHMTCCRQSQEQITGH
LHKARRLGLKNILALRGDPVGEQWEEEEGCFRYARDLVKLIRSEFGDYFDICVAGYPKGH
PDAESLEDDLKHLKEKVDAGADFIITQLFFEADTFFHFLKACSRMGISCPILPGIFPIQG
YHSLRQLVKLSKLEVPQKIRDVIEPIKDNDDAICNYGIDHAVSLCQELLASGLVPGLHFY
TLNRRMATTEVLKRLGMWAEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQDW
DEFPNGRWGHSSSPAFGELKDYYLFYLTSKAPREELLRMWGEELTSEESVFEVFVHYLSG
EPNQSGCPVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGWG
PSGGYVFQKAYLEFFTSRDTVGALLQVLKKYEQRVNYHIVDVKGENITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWVEKWGKLYAEGSPSRMIIQDIHDNYFLVNL
VDNEFPLDNCLWQVVEDTFELLHRPGTRGDRLRDPVP
>A0A836YWA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei EFB6|TrEMBL
MSLKDTFKNKTVFSLEVYPPKTPEGTKKLVNALTGIKRIKPDFISITLGAGGSQNNNALE
LSSMIQNDLNIPAMAHIPGIYRSKKDVADFLKQLKQHNINNVLALRGDINPDETPIGDFN
HASELAEFIKTQGDFDITGACYPQKHPESIDLVDDTLHLKEKVDNGVGHLITQMVFDNQA
FYDFRQRLKLAGINVPVEVGIMPCTNCNQIKHITELSGLEMPKKFVDIMNKYANNKEAMR
DAGIAYAVDQIVDLVANGVDGIHLYTMNNIYVAKKIWEATHSLFEATSYQLQHPSLSGSD
NQ
>A0A0D6LEU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylostoma ceylanicum|TrEMBL
MIRWIREEFGDYFTIACSGYPLGHPESPSYKADLLYLKSKCDAGAQFIVTQLFFEAEVFE
QFVRDCREMGITVPIIPGIMPIMVKLLV
>A0A2M6X4A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionales bacterium CG10_big_fil_rev_8_21_14_0_10_45_34|TrEMBL
MRPEFNLAHFLGKDILVFDGGVSTELYSRGFYINRPFEELNLTSPADVEAVYRGFIEAGS
DVITTNTFGIASPQLARFDIAEQQPDIIEAALKIARKATAGKDCKVGFSIGPIGDLVEPL
GSIGLSEVILEFAQIAKSVNANGGADFFILETFSNLDELRAGINGVRSIDKQTPILASIY
VRSQEEEKLKKFAHTIGDSGDVQALGINCGDGPSDLLRALGKLLELTSLPIIVQPNAGLP
RQINGRYFYMTSPDYLGKFAKRYASAGATGVGGCCGTGPSHIAAIKSSLAMAQSQSRSNK
DVGRNFIDIGWQVVSAERPSLQQREASRVGALLAAGKKFLSVEILPPIGLDVEKFQKSLD
AIESAGIPFVNIPDGARASTRMSSLHISSWINDRRSGQLKAIPHFTTRDRNLIALQSDLI
GAHFCGVKDVLVVTGDPPKLGNNKEATAVYDIDSIGLTYMIDCLNRGVSPMGEKLGSCTQ
FGIGVASNPTAINLETEIQRWKYKVESGCDYAITQPIFDPEAFLAWKDSVGSNYRPHFIG
IWPLISLRNAEFMANEVPGIHVPTWVIEEMSKAGDNKEEAIKRGIEIAQKVMHRLDSECE
GYCISAPLGKVSVVLDLLGKQVD
>A0A432Q8A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp|TrEMBL
GSKGVFDMDSIQMLGMVRDMRDAKKFQCGEEIKGSAPELFLGAAANPFAYPFEFRAVRMG
KKISNGADFIQTQIIYNVEKFARFMEMARELGLPEKAYILAGVTPPKSLGMARYMKKFVP
GMDVTDEVIDRMKGAKDKKQEGINICVDIINQVKEIKGVAGVHVMAIEWEEAVAEICESA
GLLPRPTFDEVASSTVELTPSVASDQAVEIRSQDAVTDDVMNKAREEAASIVAAARLEAE
TILSGAKPVTTTTETAAIATDDAGEHEMNEKERQMALESVNQGLKALKSAYGLSDDQFEA
LLNFASAEAVLKRDPAIGAHPSSAPVATAAAPVPAAAAKPAVDDAAKKAEEAAAAKAKAE
TAAQAESEARAKAEAEAKAKKEAEAKAADAAAQKAKAEAAAKAEAQAKAKAKAEAEAKAK
KEAEAAKQSKPAPVAKAVKAAPAAGLAASVLSVEGTPFAERTTKVPASAYKVDYSGSIRE
VTLGNGENSITVGGSNSMPFHLFEGDMQHKPLIAMEIQDIRPDNWPETLSQYFDDVMDSP
VDWAKKCVEEYNADALNIWLIGTDPNGENRPSADAAKDAAAVIEAVDVPIIIWGCGNSEK
DTDTLREVTSIIGDKKVCLAPLEDANYRAIGATAMAFQHPMVAASPIDVNLAKQLNILLE
NLGVPLDSVLMDPSIGALGYGIEYTYSVMERIRIAALTQKDEKLQVPIICNLGREVWKTK
EVGLPSEELMGDQEQRGIMMEAMTASCMLMAGGEVLIMRHPKAINMTKSLINGLIA
>A0A7L2VD61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachypteracias leptosomus|TrEMBL
MVNETQHPCSTSSSSRSDAGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFEDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSENFLK
FMKDCQGIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPR
>D3DGX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6)|TrEMBL
MKIGELLKKGTFSISFEFFPPKTEEGERELFDTIKSLECLSPTFVSVTYGAGGSTRDRTK
RVVERIHQQTHMTVMAHLTCIAHSREEIISILREYKEIGIENILALRGDLPANMPNFKPP
DGACKHANELVRLIRSSFGEHFSVGVASYPEGHPESPNMEWEIRYFKKKVMEGADFSITQ
MFFINDYYYRFIDMCYKEGIDIPIIPGIMPITNFRQISKFASMCGATIPDDLIKRLEPHM
DDQEETTKIGVEFAIKQCEDLLKNGVPGLHFYTLNKSRATLEIYQAIKDKVLALRSYLP
>A0A229GM44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NBS 14/10|TrEMBL
MDLQQRICDRAGEFLFLAVTPPRQTTTPERAQEIADVTRKRLDGLEPDGLVLYDIDDESD
RNPAERPFPFTQTMDPAEYLARHFGELDLPVVVYRAVGKYDESDFRSWLTEQPDRVLSVF
VGAASRETPVATTLSRAQLLRAELRPDLLLGGVAIPERHTRTGTEHLRLLAKQEAGCSYF
VTQVVYDVNAAKDLVSDYRYECAARDLAPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWIH
NELQHADDTLQASFEHALATARELMTFCRRLEVPFGLNVESVSIRREEIEAAVDLAARLR
SELCR
>A0A4R7HVM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ilumatobacter fluminis|TrEMBL
MTTFSFEVFPPKTDAGLVQLAEAVAELEQLRPSFVSITYGAGGSSRDRSFETISTVARQG
STMAAHLTCVGQSRADLDDVIDRYLSLGVSHVVALRGDPPEGIDAPYAPHPDGYTSTAEL
VAAAKARGIEHISVSGYPEKHPQSPSDDHDMAILAEKAAAGADRAITQMCFDTEATIRWI
DRVRSAGIDIDIAPGIFPIHSFPAVARFAARCGASMPAEVAERFAGLDDDPDTTAKVGAE
FAAQQIARLREHGVRHVHLYTLNRAPLARAVTEQL
>A0A1Q6VLV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium 13_2_20CM_54_12|TrEMBL
MHITDIMRGDSPTFSFEFFPPKTAQAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
GLVERIQHTTKLDPIPHLTCVCHNEEEIEAILLRYAQSAIGNVLALGGDRPVGIAYDKAR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLLEMDHFKAKVDAGA
NYIVTQLFFDNRDFLDFRERCALVDINIPIIAGIMPITTLNGFKRIAELAGGARFPARLL
RALQRCQNDPEMVRRVGLHFAIEQCHDLLDNDVAGIHFYTLNRSDATRMIFDSLGIPRRR
NAEPSSV
>A0A1C5CRM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DconLS|TrEMBL
MLAGGKTTYSFEFSAPKTPKGERNLWTALRRVEAVAPDFVSVTYGAGGSTRAGTVRETQQ
IVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGAWVAHPKGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVVEAGCDTPVIPEILPVTSVRMLERLPKLSNAQFPDALKERILAAKDDPAAV
RSIGIDFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLGLHHPPQA
>A0A4D6MYP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vigna unguiculata|TrEMBL
MKIIEKIRAAAADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANRMQNIVCVETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVKHIRAKYGDYFGITVAGYPEAHPDVIGSDGLATAEGYLKDLEYL
KSKVDAGADVIVTQLFYDTDTFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPADIMSALEPIKDNEEAVKSYGVHLGTEMCKKILSHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALTDYQFMRPRARDKKLIEEWVVPLKSVEDIYERFRMYCIGKLRTNPWSELDGLQP
ETKIINEQLERINAKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKL
DTLVDKCKDRTFLTYMAVNKEGCWKSNVGQTDVNAVTWGVFPAKEIKQPTIVDPVSFNVW
KDEAFEIWSRGWASLYPEGDASRKFVEEVGGSYFLVSLVDNDYINGDLFAAFADF
>A0A1G3HFP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclales bacterium RIFCSPLOWO2_02_FULL_63_24|TrEMBL
MSLELSIEFFPPQTAEGMEKLRATRSRLAVLKPEFFSVTYGAGGSTRERTLETVMEIATE
GYCAAPHLSCIGSTRAGIREMLGIFIERGIRRIVALRGDLPSGMADAGEFRYANELVAFI
RAETGARFHIEVAAYPEWHPQAKCPREDLLNFKRKVDAGADSAITQYFYNADAYEHFVDE
ARALGVTVPIVPGIMPIGSFSKLARFSDACGAEIPRWMRRKFECFGDDAESIRAFGLDVV
TELCQRLIERGAPGLHFYSMNQAGLTLELCRRLGLGAAR
>A0A0Q8C5M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia sp. Root60|TrEMBL
MAIELPSTEDAARLPVSFELYPPRTDAAAIALGRTIDRLTEVDPAFISVTFGAGGSTRDR
SLTVLSYILENTRVEPMAHLTCVGSSAAEANRLVRQFLDAGITSFLALRGDPPLDGTPLS
VGDLQSAAELVQLIHRVQQEREPFSQEAVRGTPGGTRLRARPRPERVAVAAFPNGHATSR
GPQQEIDALLAKQASGANLAITQLFYRADDYLAFVERARAGGVTIDILPGIMPAASAPRL
RRIAQLTEEEAPDDLLIALEIEPTEEGRSEIATSFFSDLAAEVIAEGAPGLHLYTHNRHT
PVLDVLERLDRLPRTARGHIKENA
>A0A1G9RG12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geoalkalibacter ferrihydriticus|TrEMBL
MSRFAEKLAGGEFVVTAEIAPPKGVSLDQELALAASLPAEVTAVNVTDNQGANMRMAPLA
VAALLRQRGIEPILQMTCRDRNRMALQSDLLAASALGIENLLLLSGDHPRFGDHPQARPV
FDLDSVQLLRAAEALMAGHDLAGRPLQTSPVFFPGAAVTPEAEPFELMFQKVQKKAASGA
RFFQTQAVFREESLRRFMAQARPLGVPVVLGVILLKNVRMARYLNEHIPGVRVPEDIMTR
LSEAADPLEQGVIIAREMVALARSECQGVHLMTLGCEDRIPQILC
>A0A849C346|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia uniformis|TrEMBL
MSFDNVRGSSTPGRVSRTLQVSGTPSVVQQLGPRPDGSIPFSVEFNPPRDAAGEARLWRA
AREFERMHPAFVSMTYGAGGSTRDRTIRVTGQLARETTLLTVAHLTAVDHSVAELRSIVG
AYADAGIRNLLVLRGDPPGDPLGEWIKHPEGVEYADELVRMVRELGNFHVGVASFPQGHP
RSRDLDEDTRFLVAKLRAGAEYSITQMFFDVDHYLRLRDRALTADPVDGAKPIIPELMPI
TSLRTVQRAEELSGRALPERVIERLRKAAGTGPEENREAVRAAGIEIATEMAQRLIDEGA
PCLHFITLNFAKATSEVLANLGYTVSPTPVRA
>A0A1H6QAP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium A10|TrEMBL
MRLKDYLKENILLTDGATGTYYGELYPESNLIVEQVNLIHPDQMVELQLQYLRAGSRFLR
TNSFAANLKFFPESDIRLQIVRKSYQIAKRAVERFREESGFDGDIYIAADLGTVFDGEII
GSASVFEEYRENIDAFLLEDADVFLFETQADTSLLRELATYIKTKKPDAFVCATFSLDKT
GFTKAGLSLGRLLRQLHEIPELDGYGLNCGMDALHMLYQVKQMHFYDDRPVFSIPNSGYP
YMLRGKPIYAKNADYFVQNVCAMLRCGVSVVGGCCGTTPEHIRKLHDAIQNKKPVERYIS
EYEPGEQVRTLSSFWKKLQTGEKPFIVELDPPFDIDISKVQSGARMLKEHDVDLLTLSDS
PLGRTRMDSLQLAAKLQHEVEIQVMPHVTCRDRNIIALRSHMLGSYMNDIRHYLIVTGDP
VPVQDRSTVTAVFDYNSIHFMHLIKEMNQEIFKGDTVVYGGALNYHGINADAIARRMKQK
MQEGCGYFLTQPIYSEEDIERIQYLKEQTGAKICCGIMPLVSYKNAYFIANEMPGIRVPK
EIVDAYKEDMTREESEAIAVEISLSIARKLYSIADGFYFMTPFNRVSLICRIIDRIREEL
>A0A822LW56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides vulgatus CAG:6|TrEMBL
MGIAELINKKKKTAFSFEVLPPLKGTGIEKLYATIDILREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKDGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVEAGADYVVTQMFYDNRKYVDFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAMKCKDDKEARALGIEWCINQCRELIAYGVPGIHF
YTVGAVDNVKEVATAVY
>A0A6L5Q783|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. RIT694|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPFHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGILISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1Y3D9Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4973|TrEMBL
MSQLSTCFTQNQFCVLVEYLCSMKEILPVKTQFAGFAALMTLADRVHADDDLAPIIAAQA
YPKHIEKVLHFAGKGRDIRDFEQFLNDAQAIGQQNLLLLTGDKLKNHHKGKDFSERTRYL
ESVNAVMAAKQHAGFCIGVAFNPFKYAEAERDAQYLKLHKKLKAGADYIITQLGYDLSAL
KEAKAFLTQHGYAQKILACVMPLTLGRANFMVKHQVAGIVITPHMLKILGEEKESGLTDR
VYLRCALQILICKQLGFAGVHLSACHKPEEQLLLESYIEEYRHLGLDELELLWNTLWQVK
TGNEFYPALTYYSRPVSSMQILKYQHLHLMHDALFESKVAKGVGNFIFQSRFWNGSLAAQ
ALLKTEFVSKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVDQTQILKNNLILTVPIEVRGSSSWKNWYVNQAS
>A0A3S0W4U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peribacillus cavernae|TrEMBL
MDFREEVKTSILIGDGAMGTLLYSNGIDNCYEELNISEPERIETIHSAYLDAGANILQSN
TYGANYYKLKRYGLEDEVSTINRKGISIARKAAKKKAFVFGTIGASRSIRKSDLSLEEIK
RSFREQLYSQLMEQPDGLILETYYDIEELETVLQLARNETGLPIIANVSMHEIGYLQNGI
HLNEAFQRLGELGADVVGVNCRLGPHHMIRSLEEVPLPKHAYIAVYPNASLPDYVDGRLV
YEAVPDYFGSSALKLREQGARIIGGCCGTTPKHIKAVKQALGDLQPIKEKEIKARHIEII
EINDNDTTIGLHEKAKTERTILVELDPPKKLGIETFLAGAQVLHDAGVDSITLADNSLAT
PRISNIAVGTMLKNQVGTNPLIHITCRDRNLIGLQSHLMGLQTLGLEELLIVTGDPSKIG
DFPGATSVYDLSSLDLISLVKQFNEGLSYSGQSLGKRSNFKIAAAFNPNVRYIHKAVQRL
EKKIACGAQSFLTQPVYSLDQIEEVYEATKHLRTPVFIGIMPLTSSRNAEFIHNEIPGIK
LPDDVRRAMAAAGSDPVKARTEGIAIARNLVDAVMEKFKGIYLITPFLRYEMTAELSQYI
RKIDSERFAEVTAHD
>A0A6L9QHV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura bangladeshensis|TrEMBL
MGFEVVCEVEPPTRPDLQKVRHQIGVLSPVADSFLIPDNHIGRATVSSVAVAHEVQAMGA
RGIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVYGDKPRAGGRTSELTVRAMMEEARAA
SEDEVFAGCGPFQVGVTSGLRAVPMWKRAADFTFVQVSYSVENLVRWRESVEVDGPVYAG
VMVLASAGMARNLAAAIPDIDIPAELVEAVERDRAAGVAAACEQVLAIRDSGAFDGVHLV
PVSRYREVAARLERDL
>A0A829YN60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steroidobacter agaridevorans|TrEMBL
MTQPKAEAMPEPVVDQAGIATLARGCSIEMNVQDAPQLRRARSLLSPGKKVYVSHLPKQT
WQQTIDACHEVREVGFEPVPHVPVRLLDSARTLEEFLHQAANRAQVAEILLISGDYPQAR
GPYSTVAEVLRTGKLGEFGLRRISMAGHPEGHPQVPLPEIRRAEREKAELAQAAGLQATL
LTQFFFEAPPFVEWAAGLRADGVRARLVAGISGPASIATLLRYAVRCGVGPSIRALGARP
TSMVKLIGDHGPEQLMRTLAGVPRPDVYDGLHFFTFGGFLRTCEWLQRVGAGEFTLDRHG
GFRVD
>A0A7U5ZS55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae complex sp. FDA-CDC-AR_0132|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPHWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGA
>A0A8H4VCF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps camponoti-floridani|TrEMBL
MAVDKITHKIAALPDGVDYFSLEFFPPKTAMGFANLRHRLQRMEQALRPLFVNVTWGAGG
ATAIKSLELAELCQRELGLTTCLHLTCTNMSRRLIDKTLEDAKVLGIRNILALRGDAPRK
EEYREAMADDYDQDDDDSVDFAWAIDLVRYIRSKHGDYFCIGVAAYPEGHAVGSHPEVQS
LEYDLPYLVDKVRAGADFIMTQLFFDADAYEKFERTLRDHPSGVFATLPIIPGLMPIQSY
QMIKRTTKLSHARMPDAFTARLDEVKGDDERVKKIGVDIICELIEQIRAMGSGSPGRRGF
HFYTLNLEKSVSLIVEQTGLIQEDSSDEAVSDALLSPPPTLHVNGYGPLRPGGGHSRSSR
RQSSVGSDPHNRVIVGDRPLTNPEWETTGQEAGVPASSVNSRANTLAISEGEGVLGREAT
WDDFPNGRFGDARSPAYGEIDGYGVSLHMSVTQAERLWGHPTTREDIDGIFVRHIRGELA
AIPWSEEGLMAESSTIKDQLVELNSRGWWTVASQPAANGAPSSDRTLGWGPTNGFVFQKA
FVELFLPGSEWRTLWERLQRPGTRDSICFYAANARGDFASSDESGGAKDAGSAPSTNAVT
WGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWREWARVYGMGSASEKLLRGIGDDYWLVNV
IHHEFVETDALWDLLLGRE
>A0A1B8WML7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. FJAT-26390|TrEMBL
MKPDLREALQQRILTGDGAMGTYLYQMGFPVGVSYEEFNTIRPDVIENIHRRYYEAGARV
IETNTFSANLEKLSKYGLEDEMDAINRAGVRVARAAIGDDAYVVGAVGSVRDGKLKNLRT
AKVIEAYQRQMHALLDEGVDGLLLETFYDLDEMLLALRIARSASNVPVICQFAVEDVGRT
QDGNGMKSAFDQLQEAGADVVGFNCRSGPNGIMRAIDSITGPVGLPLSVYPNAGIPDYID
GKYAYSAGPEYFAESAMRFADRGARLIGGCCGTTPEHIKAIAAALDGYVPQLGQAVASHA
AVETIVVKPAEKPAASDTAPQKVEVQEPTIVDLVLKRHTVIVELDPPRDLDIRKFMDGAA
ALKEAKADAVTMADNSLAVTRMSNIALAALVQEKVGIRPLVHIACRDRNLIGTQSHMMGL
DALDIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNDGTAFSGKPLKQKAKFV
VGAAFNPNVKHLDKAVQRLERKIASGADYIMTQPVYDPGLIERIAEATKHLTVPVFIGIM
PLASGRNAEYLHNEVPGIQLSDEVRQRMSGLEGEAGRAEGVQIAKELLDAALPHFKGIYL
ITPFMFYDMGVQLTEYVWQKTERM
>A0A7U8KY46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella melitensis bv. 1 str. Rev.1|TrEMBL
MGFYGLSCRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>S3VWX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira fainei serovar Hurstbridge str. BUT 6|TrEMBL
MKKILEIYTNAKEPVYSFEFFPPKTNEGEAKLYETVNELSRVNPGYITVTYGAGGSTRDK
TIRLTSDLAQKFNLAAAAHFTCVGGNKEEIHNILKEIESSGIRNLMALRGDPPKGEGAFK
KVDGGFEHASELISFIKSEGFDFCMGAACYPEKHPQATDLEQDVDNLKKKVDAGADYLVS
QLFFKNEIFESFLNLVRKKGINAPVVPGIMPITSFSQIERFRSMAACEFPDKLLTDLEEV
QNRPEEFYRRSLNFSVEQCRELIEMGSPGIHLYTLNQSHASYDIVRELRGEGK
>A0A1C6LAD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKLSEAMRERMLLSFELFPPKTEKGMDNLPGTIDHLMKYKPAYISCTYGAGGGNVGANRE
VCQMIKKAGTTPVTHFTVIKNTKEGIKEQLDQYLAEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDSIREAGVTMPVDVGVMPILDMSATINMALSRNGCVMDRELCRLISRNWLFPN
PFAAKDADGKPFDMFYDDKIKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLCTLI
>A0A1C6EAW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKISELLKEDKVTLSCEIFPPKTGAALEKIDAVVRDIAALHPAFISVTYGAGGSTSKRTA
EISNKIQNQYGIPALAHLTCVSSTREEIAGMLARFRAEGIENILALRGDIPQESDFPSPE
HYHYASELVEDIRRQGDFCIGGACYPEGHIECAHKEDDIDFLKRKVDCGCDFLTTQMFFD
NNVFYNFLYRALAKDIRVPIVPGVMPVINAKQIRRSCELSGTVLPPRFKAITDKFADNPR
AMKQAGIAYATEQIIDLIANGVKHIHLYTMNRPEIATKIMDNLSDILG
>A0A1C5PFM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKIRDILNKDTATISFEVFPPKKSTDFGNVEAAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGEIQKQHNVPTVAHLTCVCADRGSIGTALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKKNGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIVPGIMPITRGVQVRNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIVYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNLSEILKA
>A0A069IPR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. EAKA|TrEMBL
MAASSTNLAEARALLLSPLGPVARAGSNHDAVRVSFEFFPPKTDEAEANLWTAIRRLEPL
NPAFVSVTYGAGGSTRERTHRTVQRIIAETSLRPAAHLTCVEASRDEVDEVIAGYKSIGV
DHIVALRGDPPGGGGIGGVYQPRADGYANATELTAAISRVGGFDVTVGAYPEKHPESPSI
DHDIDVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLTR
MCGACGTSIPDWLKAHFDGLDDDPETRRLLAASVAAETCARLHEEGFSDFHFYTLNRADL
VYAICRVLGVREQKAAA
>A0A6J6DQJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVLGTSYSFEFFPPKDAEGEERLWHAIEGLKSIAPDFVSVTYGAGGSTRDRSIRIAREIT
DRTGIPTVAHITCVGSTRDELLEILHSYQDAKITSILALRGDPVGGPLAPWIPTENGFAH
ADQLVELARDCGGFTIGVAAFPDGHPSSGGDFNKDIDVLIRKEQLGATFATTQFFFDVQA
YVNLVERLAKRGSSLTIIPGILPVTNVKLLHRMAELGGTPVPPDIAKAFADVESDTQAVR
NLGVEIATKLCQELLEAGAPGLHFYTMNSSTATVEIYRRITNAQ
>A0A0K8P9U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flexilinea flocculi|TrEMBL
MNISELFKIKKVVFSLEIFPPKKDNSVNVIYNTLLKLRGLPVDFMSVTYGSGGNISQREK
TCEIASLIRSAYHIEPVAHLTCVNSDEEEIRETLKKLKENQILNILALRGDINPDVPPKK
VFQHASDLVRFIQETDPDFNIIGACYPECHYESNSIEEDIQNLKKKIDHGVTHLITQLFF
DNRNFYSFLEKVRQTGITVPIEAGIMPIVNKNQIERIVSMCGASVPAKLAKIINRYADNP
TALKDAGIFYATEQIMDLIENGVQGIHLYTMNNVETAARISDNIQNIIAAENDKSGIQ
>A0A6J6QKP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MNQQSTLGPRKSLLLRPTISFEFFPPKDDQGESNLHATIEALKKFNPDFVTLTYGAGGST
RDRTVRIAAEIILRHQIPTMAHLTCVGSTRDELTEILREYTKAGVKDLLALRGDPVGGPT
SEWISTPGGFDYADQLVDLATKVGGFNVGVAAFPDVHPASHGNFQQDIDVLLRKEELGAT
FAITQFVFDSERYAQLLFTLRDRGSKLTLYPGIMPVTNYMQIVRMLELSGGTMPSATRLK
FARYQNDPASIKELGIEVAARICEEVFEVGAEGFHFYTLNSALATSQVVSALSMLNFSS
>A0A8J6RYJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichocoleus sp. FACHB-90|TrEMBL
MPTIQNSMLFKSFRSAAEAGEFLITAEVAPPKGGNPVHMVEMAQTLKGRVHAVNITDGSR
AVLRMCPLAASVILLQHGIEPICQMACRDRNRIGLQSDLMGAHALGIRNILALTGDPVKA
GDHTDAKSVFDLESVRLLGLIKKMNLGFDWNDKPLTDGATDLFAGAAVDPQLASWSGLQS
RFERKLEAGAQYFQSQLICDFDRLEKFMDKIAAGCGKPIMAGIFLLKSAKNAQFINRCVP
GVNIPQDIIDRLAAADDPLQEGMAIAAEQVKLASQLCQGVHMMAVKREDLIPEILDMAGI
APLNQLVSAGTEDERTNNKATANSVAL
>A0A094QM35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSSLEHKLLNTTETVFTAEFHTLDGNGFEKAKKYADRFRGWFDGVNATDNTAAHAHVSNV
ASAIAMKQLGLEPILQVVCRDKNRLAQQADIMGASMFGVENFVALTGDDVTAGDETEARR
VFDLDGPQLVRLMSTIKRGEYMSGRKIDPAPHMFIGAVENPGAPPFEYRVQRVAKKYAAG
AKFLQLQICYHQDRLEKFCAGVRDAGLAGKIAIIPTVVLVKGSRPLNFMHNSVPGIDVPA
DQIARVEKAADPAEEAYLQTLEVAQHALAQPGVRGLHITDFRNDETLERLMTDLGRVRDL
TTNSSTTNEVKDDHAYSA
>A0A6J6N8Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MNQQSTLGPRKSLLPRPTISFEFFPPKDDQGESNLHATIEALKKFSPDFVTLTYGAGGST
RDRTVRIAAEIILRHQIPTMAHLTCVGSTRDELTEILREYTKAGVKDLLALRGDPVGGPT
SEWISTPGGFDYADQLVDLATKVGGFNVGVAAFPDVHPASHGNFQQDIDVLLRKEELGAT
FAITQFVFDSERYAQLLFTLRDRGSKLTLYPGIMPVTNYMQIVRMLELSGGTMPSATRLK
FARYQNDPASIKELGIEVAARICEEVFEVGAEGFHFYTLNSALATSQVVSALSMLNFSS
>A0A6M8B5I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleptolyngbya sichuanensis PKUAC-SCTA183|TrEMBL
MVTSSSLPAEPRSLAPSTRLQAAARSGEFLITAEVMPPKGCDPTHMLQMAHLLKDWVHGV
NITDGSRAVLRMSSLVSAALLLREGIEPIYQVACRDRNRIGLQADLMGAQALGIRNVLAL
TGDPIKAGDHPDAKPVFDLESVRLLRLIGNLNAGLDINEKPLTDGATSFFAGAAVDPQCP
SWSGLQRRFERKVEAGAQFFQSQLITDFDRLDKFMHQVAAGCNRPILAGIFLLKSAKNAQ
FINKNVPGAQIPQHIIDRLETAAHPLEEGVAIAAEQVQMARQLCQGVHMMAVKREDLIPE
ILARAGLGKVSAVKR
>A0A091P970|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haliaeetus albicilla|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQESGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRYLKEKVFASPNSKSPSTKSRSSTCVK
GLGKMKIPCILIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNFGVEQAVSMCR
ELLDSGVVHGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWAVSAHPKRRVEDVRPIFW
ASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTG
EESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPN
INGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQN
ITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRM
IIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6J1EQ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cucurbita moschata|TrEMBL
MKVIDKITAATAGDGGRVVFSFEYFPPKTEDGVDNLFDRMDRMVAHNPSFCDITWGAGGS
TADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQ
DKFVQIEGGFACALDLVKHIREKYGDYFGITVAGYPEAHPDVIGSNGVATAEGYQSDLAY
LKKKFDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTSFCK
TKIPDEVMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHMYTLNMEKSALAILM
NLGLIEESKVSRSLPWRRPTNVFRIREDVRPIFWANRPRSYISRTIGWDQYPHGRWSDSS
NPSYGALTDYQFMRPRARDKKLLEEWALPLKSIEDVYEKFMKYCLGKLRSSPWSELDGLQ
AETRIISEQLGKINMKGFLSINSQPAVNGEKSDSPSVGWGGSGGYVYQKAYIEFFCSREN
LDAVVDKCRGLPSLTYMAVNKEGIWVSNITQNDVNAVTWGVFPAKEIVQPTVVDPASFLV
WKDEAFEIWSRGWASLYPEGDPSRKFLEEIQSSYYLVSLVDNNYVNSNLFAALEGF
>A0A7Y4T3K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospiraceae bacterium|TrEMBL
MKVTECFEQNKGKTLISFEVLPPLKGGSIDILFDQLDPLMEFKPPFIDVTYHREEFIYKQ
KDSGYFEKVAIRKRPGTVGICAAIINKYKVEAVPHLICGGFSKEETENALIDLHFLQITN
VLALRGDARKFDDKFLPEKDGHEYAVDLVKQIASMNKGIYLDDDIETGMPMDFCIGVAGY
PEKHFESASLKSDLKYTRKKIEAGADYIVTQMFFDNKKFFNYQEQCRKEGIEVPIVPGIK
PITKKYQLNAIPRNFFVDMPDDLVRSIQKAKTEEQVIEAGIEWCVYQSQELKKAGVPCIH
YYTMSDSAIVKRIVSQVM
>A0A2C4MKI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGILISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A328P8P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella jiangningensis|TrEMBL
MPSISFEFFPPKTDEQRAQLDQAATLLKSLSPEYVSVTFGAGGSTLSYTGETVARLHGNH
GLNVAPHLSCVGGTRAELAELLDAYRAAGYRRLVALRGDLPSGMASPGDFRYASELVRFI
REYTGDHFHIEVAAYPETHPQADDALADLRHFKAKVDAGANGAITQYFFNADAYFRFVDD
VRRLGVEVPIVPGIMPISNFSQLKRFSDQCGAEIPRWIVKRMQAHGDDAASVRELGADVV
AEMCRRLLDGGAPGLHFYTLNRARATQAVLNRLHS
>A0A3N0GWZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmoricola pocheonensis|TrEMBL
MDLQRRILERRGEFLLFALTPPREATPAVRVQEIADVTAKRLQDLDLDGLVLYDIDDESD
RNPEERPFPFLPTMDPAEYLSRHLEGWNIPTVVYRAVGKHAEPELRSWLSTQEPDRVLTV
FVGASSRTKPVATSLRRAQDLRAEAAPDLLLGAVAIPERHTRTGEEHLRMLAKQAAGCSF
FVTQVVYDVNAAKNLVSDYLYECVQRSVDPVPIVFTFSVCGSMKTLEFLQWLGVDVPRWI
QNELRHAEDTLEASFDQAFATARELIAYCRRVGVPFGINVESVSNRRSEIESSVNLAARL
RDELDGSA
>A0A1M6F7J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenitalea lutea|TrEMBL
MKVTDHIKHSKGKTLFSFEIIPPQKGRNIQELYNNIDPLMEFNPPFIDVTTSREEYVYID
KGDGLLDRKITRMRPGTVGICASIQHKYNVDAIPHVLCGGFTKEETEYVLVDCHYLGIQN
VMALRGDAMSHEKYFKACAGGHEYATELVAQIQNLNTGKYLHDVIESEHKSDFCIGVAGY
PEKHMEAPSLQTDLRRLKEKVDAGADYVVTQMFFDNNKFFEFVKAAKAIGINVPIIPGIK
PIAVKRHLQLLPQVFKIDLPEELIVEVEKCKDNKAVRQVGIEWAIKQSRELREAGVPVLH
YYSMGKSDNIKAIASALF
>A0A2C5WWI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceratocystis fimbriata CBS 114723|TrEMBL
MDKITDKIAALPADASYFSLEFFPPKTDMGFSNLRNRLDRMEKALHPLFVNVTWGAGGST
AQESLQLAETCQRELGLTTCLHLTCTNMSPRLIDKALEDAKALGIRNILALRGDPPRKAE
YADANASAETQGDASTEFNYAIDLVRYIRKNHGDYFCIGVAAYPEGHADGSHPNGHSFDN
DLPLLVEKVQAGADFIMTQLFFDVAAYADFETKLRAHPSGVFNTIPVIPGLMPIQSYQMI
KRTTKLSHAKMPQALMDRLNAVQADDEQVKSVGVDILSEIITEIKRLKSGTPSPQGFHFY
TLNLEKSVSLILEKTGLIPDTDENEEAVVADDHDVSAPMRANGLMPPSVAANTQASHTTA
RRLSSIGSDPRNRVIVSAGSVGNSEYVVSAQDASLLSKPINTRANTLAASEGEGILGREV
TWDDFPNGRWGDARSPAYGEIDGYGVSLHMTPSQALQHWGYPVTADDINTLFLRHIQGDL
SALPWSEEELRPESSAIQRHLEALDMRGWWTVASQPAVNGVKSSDTTFGWGPANGFVFQK
AFVEFFLPSSAWKVLLERLRDPAVKDQVCFYASNARGDFVSSDRLDAGAADTDPATQGTT
TAQVSDGPTPAEIGPSTNAVTWGVFPGKEIVTPTIIEEVSFSAWSEEAFGIWGEWARVYP
PNSASAKLLEGIRHDYYLVNVIHHDFVEPNALWDLLLGQE
>A0A4S0RVS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M8A.F.Ca.ET.213.01.1.1|TrEMBL
MTGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHEDITETQVDMVK
TAH
>A0A1J5BTJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium CG2_30_59_46|TrEMBL
MGITIPIVPGIMPITNFSQLARFSDACGAEIPRWLRLKLQGYGDDTAAIRACGLDVVTSL
CDRLLKGGAPGLHFYTLNQAGLISTIWQRLGL
>J9HCE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicyclobacillus hesperidum URH17-3-68|TrEMBL
MKGDSGMPSGGWETWAKVPRELAVAGGRYVIFDGAMATYLHQCGVPIRVCAEELNLSKPR
LVEQIHRAYVEAGATVVQTNTFAANRLDLARHGLDAQTVAINEQAVLTARAAVADRASVY
GTMGPAAGGTRYGALLTADERSRLSQVYEEQAFALIEAGVDGIVLETFPDLEELLLALRV
VRVMAPQLPIVANLSPEEVGVTRDGVLLTKAFATLREAGASVVGLNCRLGPYGILRSFEQ
IVFDDGPYAAVPNGGILHRSESEGLAYTGDVDDFARVMSDIARLGVRWLGGCCGTTPEHI
HKLVLALQAQDRGETWAEPPQKPSSIHVVADNRRDEMEGMGAETPLGPSIVDTLKERTAV
IVELDPPKHLSAARFLAGATALSEAGADMITMADNSLGSVRISNMALASVLKQRGIEPLV
HVTCRDRNLIGQQSHLMGLHVLGVRNILLITGDPSRYGDLPGATSVYDVSSMDLTKMVRK
LNDGVGFSGKPLQRPAQFVIGTAFNPHVHNFAKAVDRLRRKVEAGADFVMTQPVYDPVLM
EQIAEATRDLGVPILIGIMPLTSARNAEFIHHQVPGISIPADILSRMRETAPEEAQEVGM
EIAKSLVDRALTYYRGIYLVTPFLKFEITVRLTAYIRERTATAVASAARRE
>A0A4Y7ZPC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychromonas sp. RZ5|TrEMBL
MYSSNLKSMTTDPKRGVYFIGTTPPKQDTDLELVAGIADKLLGRLAEIDYDGLIVYDIQD
ETSRTDKPRPFPFKYTHDSRLYSKIIHDKVGKPVITYKSVSQRDAADFSKWLSDAWHQFS
VRDIVLVGSPSSDGEIKLPLADAYEALASHPQDFHLGGVTIAERHVAKGDEHVRLCHKQK
QGCDFFISQAVYNAQATIDLLTRYANECKQQGVQPKRIILTFSPCGSAKTLEFIEWLGIS
IPEATSLRILGADNPLKESLQISRNNFEQILQAVLPLNIPLGLNIESLTNRKEEIDAAIL
LFKLLKATLDLKLAESQL
>A0A7K6CFZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ptilonorhynchus violaceus|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRCLGNSSSPAFGELKDYYLFYLKSKSPREEL
LKMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRR
GILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVN
YHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAK
LYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6N2U652|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides uniformis|TrEMBL
MKVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A527U9U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRAYMQKVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDQVVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A2S6TUX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha3_Bin3|TrEMBL
MTGNTPPEANGAPHLAVAAPLPRDVRVSFEFFPPKTEKANKTLWDSIQRLAPLRPSYVSV
TYGAGGSTRERTHATVYRIRHETTLEPAAHLTCVGATREEIDDVARSYWQAGVKHIVALR
GDPPEGQDRYRPHPGGYAYASDLVAGLKKVADFEISVAAYPEIHPEAESAEDDIDNLKRK
IDAGASRAITQFFFDVEFFLRFRDRVQAAGITVPLIPGILPVTHFTRVAGFSAKSGASMP
AWMGELFEGLDDDPETRKLVAASVAAEQCRALHAHGVTDFHFYTMNRADLVYAICHILGV
RANDGA
>A0A2E8MDX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MNSKPAITGDALRASVEETAGRLAGRPRPAVATLRSEPEISFEFFPPXATGXEHFXATLE
ALDPLGAXFMSVTYGAGGSSQERTLAALQAINSRCQTPAMGXXTCIGASRXSVLXVVDXY
AAAGXXRILALRGDPPAGTTEFXAHADGFDGXVXLVAAIAXRGXFDLXVAAYPEKXPQAR
SXAADLDHLKRKLDAGARRAITQFFFEPDTFLSFRDRAAAAGISAPIIPGIXPVMNLPRT
XAMARQCGTXVPAWLGQLFQGLDDAPQIRQLVAATVTAELCTRLQDQGVHQFHFYTLNRP
ELTWSICHILGLRAAGSGNVAANLNQRIPAA
>A0A1E5X418|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. J237|TrEMBL
MSKERRYSFEFFPTKTEAGHEKLLATARELATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVETAPHLSCVGDSKAELRELLALYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VSFIREETGDQFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVDRVRKMGIDLPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIESIQAYG
EQVITEMCERLLQGGAPGLHFYTLNQSAPSLAIWNNLKLPR
>A0A2N1R4A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetae bacterium HGW-Spirochaetae-7|TrEMBL
MGRFTMSSVLDALAAAPRRISMEVVPPSRGGDPDGVIACVEALAPFEPAFVSVTDHPAGH
AWAERDGAPVAVPIRGKPGTLGLCVAIRERTGATVVPHLVCLGSDRFKAEDQLIDLRYAG
FTDVFVVRGDERFSPFASPGTGTGPGAPGVAGYGSLSQAVDLVRIVAAINRGDYLSDGSK
GSPAGFSVGVAAYPEKHPASPNPEADLASLREKVQAGASWIATQMVFDAGRYADFVGRAR
AAGIEEPIIPGLKPLVRARSLAGVPGTFFVDVPRALVDALTEARSPAEERLAGIRYAAAL
VGRLYDAGAPCIHFFTMGKARDAVETLEAVFGGASGAAR
>A0A1F1KE75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia sp. HMSC21D01|TrEMBL
MTQLPDSDQTGGGRHPSIVERIETSTTPRVPFSVEFYPPRDEAAEERLWRAASVFSELGA
AFVSVTYGAGGSTRDRTVRVVERIVRETDLVPIAHLTAVGHTVAELTDMVRMYGEAGVSN
ILALRGDPPGDPLGEWTAHPEGLHYAEELVRLIHEVGEYHVGVASFPEGHYRARDLDHDT
EVLVGKLRAGAEYSITQMFWDVEHYLRLRDRAVAADPEQGAKPIIPGLMPVTSLRQVKRM
VELSGCALPDDLAERLRTAAGDGPEENREAVREVGIDLTTRMCERLISEGVPCLHFNTLN
FSRATREVLTNLSMAPAPGVAASRI
>A0A1H7LY30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosovibrio tenuis|TrEMBL
MESQKRFAPTFSFEFFPPQTAEGMEKLRATRRQLAQLNPKFFSVTFGAGGSTRDRTLEAA
LEIQAEGHKAAPHLSCIGSTSENIRTMLEKYRDGGIRHIVALRGDLPSGMAQGGEFRYAN
ELVAFIRKEFDDTFHIEVASYPEYHPQANSAHEDLLNFKRKVDAGADSVITQYFFNADAY
FNFIDACEAMGIEVPIVPGIMPINKFSQLARFSDACGAEIPRWIRKRLEGYGDDSASIRA
FGLDIVTDLCDRLLSAGAPGLHFYTLNSAGLTTTIWQRLGL
>D9X286|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces viridochromogenes (strain DSM 40736 / JCM 4977 / BCRC 1201 / Tue 494)|TrEMBL
MALGTASIRSDHARTVRDMLATGKATYSFEFYAPKTAKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLGRIGSLTNAAF
PAALKERILAAKDDPAAVRSIGIEYATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A527A118|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQ
>A0A1F3ZNQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_67_12|TrEMBL
MTRNGRVFSFEFFPPRTPEGKEKLRATWQQLARLGPRFFSVTFGAGGSTREGTLETVLEI
RAAGFEAAPHISCVASTRADVAAQLERYRAQGIRHLVALRGDLPSGVAATGEYRYANELV
DFIRASTGDWFRIEVACYPEFHPQTRNAADEVRNFKRKVDAGADGAITQYFYNPDAYFRF
VDECRAAGIALPIVPGIMPIGNFSQLARFSDACGAEIPRWMRFKLESYRDDGASIRAFGL
DVVTALCEKLLAAGAPGLHFYTLNQAALTATIWQRLGI
>A0A529RAG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
EFVDFGVTRFVALRGDPAAGVGTAYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHP
ESPDFATDIDMLKRKVDNGATRAITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNF
TQVANFSSRCGALVPAWLAERFEGLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTM
NRADLVFAVCHMIGIRSHEAEATGSAAA
>A0A4R3JJB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Varunaivibrio sulfuroxidans|TrEMBL
MSPLSKHTVTSETLIAAPLAGDVQVSFEFFPPKTEKMEQNLWASIERLAPVRPAYVSVTY
GAGGSTRERTHATVTRIRRETDLEPAAHLTCVGASRDEIDAIARAYWAEGVRHIVALRGD
PAEGMDKEYRPHPEGYAYASDLVAGLKKIADFEISVAAYPEVHPQAVSAQADLDNLKRKV
DAGASRAITQSFFDIDVFLRFLEKADKAGITVPIVPGILPVTNFSRVKEFSTATGASIPG
WMADLFDGLDNDPETRKLVAAMVAAQQCRLLYGAGIKNFHFYTLNRADLTYAICHVLGVR
PNKTPGDA
>A0A528KXY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAQRLDHILHDEVTETQVDMVK
TAH
>A0A193GJV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella flabilis|TrEMBL
MTESNTPAYSLEFFPPRDIAAQERLLRAAKQMLAMHPRYVSVTFGAGGSTREGTAGTVRM
LRNLGVDAAPHLSCVGATREDLRGILASYREEGVRQLVALRGDLPSGMGGDAGELKYARD
LVSFIRQETGDCFHIEVAAYPEMHPQAENPSADLDHFIEKVRAGADSAITQYFFNPDAYF
DFVDRVRAKGVSVPIVPGIMPITNHTQLARFSQMCGAEIPRWIRLRLAELGDDKASIRAF
GIDVVTTLCRKLLDQGAPGLHFYTLNSAEAPMAIWKNLVA
>A0A529I8Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
PAAGVGTAYRPHPDGYANGAELVGAMKSAGDFDISVSAYPEKHPESPDFATDFDMLKRKA
DNGATRAITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPA
WLAERFEGLQNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIR
SHEAEAAGSAAA
>A0A439V140|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMETKLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETAIPAAAHLTCVGATRDEVDAVIHDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A8D0AJJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sander lucioperca|TrEMBL
IFQKLSVPNDEGLGYDSSGASNSSESSKESSRSSTPVLDVDRSDRLRDKMRRRMESGDRW
FSLEFFPPRTASGAVNLISRFDRMGTGGPLFIDITWHPAGDPGSDKETSSLMIASTAVNY
CGLESILHLTCCNQTKEKISGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLV
KHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTFLKF
LDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGI
KQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLK
MWGDELMSEESVYEVFTCYITAQPNRSGHKVMCLPWNDEPLAPETNLLKDELEKVNRRGV
LTINSQPNINGKPSTDPIAGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYH
IVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWKVIDDMFELLDATPEPLDATPEPLDA
TPEPLDATPEPLNEGAASE
>A0A1H3FVH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobellus clavatus|TrEMBL
MASQGLSASTTQTTTESLLENPRFELMPFDSFDEEIAHLPEGATVTITASPQLELEATIE
AAEEAAQAGYEVVPHVSARYVRGPEHLAEICERLKAVGIDDIFVPGGDREEPIGEFESAY
DMLVALDDLEYEFEEIGITGYPEGHEFLSQETLTEAMEKKAPYATYIATQLCYDPETILE
WIETIRDRGIDLPVEVGIPGVMKYEKLLNISQKVGVGDSVRFLKKTTGIVGFVKQFIGSR
GRYRPDELVDGLGPHADEYGIRGIHVYTFNQVPDTEEWRTSRLQ
>A0A0S7WU35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division TA06 bacterium DG_24|TrEMBL
MSADAGGRGVSEKAKPSRDLLARLRTQVLLCDGAMGTFLYSKGIPTDSSLEELNLSRPSL
IRDLHAAYAEAGADILETNTFAANRAKLGMHGLEGEVGRINECGARLAREGGGPEVLVAG
SVGPLGALIEPYGRLTSETARQMFSEQIRSLAAGGVDAIVVETFSNLKEALEAVRAAREC
CDLPLICQMTFLEDGSSQFGHRIRPSFDVLIDAGADVVGINCSIGPRAIHRLVVDHLGGT
SYPLSVQPNAGYPAIINDRSVFLSTADYFRDYAEEFVELGVNIVGGCCGTTPEHTAAMAE
VVRGRTPRRRHSREPVEHRVPVSVHVRGSRDAPAVSGVAPTSRFLEKLGEEFVVTVEVAP
PRDIEPSGLIESVRRLCLAGVSAVNVAENPLARLRMSSLAFAHLVKEQAGVETILHVTCR
DKNLLGLQSELLGAAVLGVGAVLALTGDPSSIGDFPRATSVFDLDSIGLVRMIAALNAGT
DIGQNPIGHPTAFRIGVAVNPAAPDLAHEVARLEEKIEAGAQFAQTQPIFDRSILEEFFA
RCGHLEIPILVGLLPLRSAKQAEFLHNEVPGISIPDEIRASMRAAPPAEQGQCGVAIARE
LAREIREQAHGLYLVPTGARFDNVLEVLKY
>A0A5E7LT24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLKQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A7L0JPG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chauna torquata|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKESSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFQSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A2E0D037|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISDKIKEYKKQKKVFYSFEYFPPKTDFGMDNLYSRIDRMSSLGPAYIDITWGAGGSTA
ERTLDMSKTIQKYFGLDVMMHLTCTNMSIKLIDEVLSEAKKSNISNILALRGDPAEGSNE
LRKENQAFNYGVDLVHYIRKNFGDTFFLAVGAYPETHQEQSDPDLDINYLKEKVDAGVDI
IVTQLFYDIDKFLLFRDKCLSKGIDIPIIPGIMPIHNYSRFRKFTQFCKVNIPENILKKL
EPIRNDDASVINFGIEQGADMCEKLVKEGVPGLHFYTLNLEHSVKEILNSIGLISDNKAN
RELPWRQSSDEIRKXSEDVRPIFWSNRPISYLTRTENWDDFPNGRWGDISSPTFGELNQY
HAIRAGSKSSEIRDKRKKIWGQPQSIKDISNVFMSFCKGDINTLPWCETKLAIESKQISN
ELIKLNESGYFTINSQPNVNGXPSDDTHFGWGAEGGRVXQKAYXEFFTSKENLDRXIXKI
KKNNNISYQAVNLSEDLISNVRKDNVNVVTWGVFPGEKIKQPTIVDTRSFMIWKNEAFSL
WMNDWASIYEKDSISYSLLXNIYENYYLVNIVDNDFIKSNMIKQIIK
>A0A1M6JCU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionispora hippei DSM 15287|TrEMBL
MFKAYLQKHSVLVDGAMGTYYAALTGRDTVFAELANLTEPAQIQAIHCQYIEAGARLIRT
NTFSANSFSLQLPQEEVKEIIKAGYHIARQAAAGKNVWVAADIGPVPEIVSGTAEGDRSR
ILAEYLFLADTFLAEGADLFVFETFSSTDYLAEVAAYIKRQRPEAFIWTQFATTPDGFTR
RGISNERIVREVKQIAAIDAYGFNCGVGPTHLYNALKNLTGRDRGDIVSVLPNAGYPEIV
NERTVYAQNPDYFAEVMEQISALGVRILGGCCGTTPEHIRKTAQRLNQSAVSPVEDRPVS
VREVLPVKAAPNRLRDKLSRGEFVVAVELDPPFDTSVDKILHNAHLCREAGVDLITVADS
PMAKARVDSVMLAAKIQREAGIATMPHICCRDKNVNALKSSLLAGHIENLRNVLAVTGDA
IASADKNEIKSVFNRTSLSFMELIAEMNRELFKEDPFYVGGALNLNVANKRVELGRMAKK
AERGAAFFLTQPIFADEVIAFLPEVKRAGATKILGGIMPLVSYRNAMFLNNEIPGISIPE
EHIRRFTPAMDRAQAETAGIQLAMELARKIKPFVDGFYFITPFNRVDMVLNILRQVM
>A0A6F8SIR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adlercreutzia hattorii|TrEMBL
METVARLFEESRENRSADARCCGVADKEGAAGRIPFSAEMFPPKGQLTLDAARKVVEGLR
AASPDFISVTCSAGGSGNGSGGQTAAIAELVQKEAAIPAVAHFTCVSATRASVDDAVEDL
RAADVKTVLALRGDLVDGQQPADFRYACELIPRLKEAELCVGAAAYPEGHIDCLDPRENI
RHLRAKQDAGADFFITQLFFNNDDFYRFREAAESAGVTAPISCGIMPFLGKSQIQRMVFL
CGSSLPAPIIKLLAKYEDDPASLRQAGIEYACNQLVDLGRHGVDGLHVYAMNQPDIACAA
AEAVAAAGLR
>A0A2K4L564|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. DP16D-R1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A2V2FAD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Subdoligranulum variabile|TrEMBL
MTITELFKTKRCVFSVECFPPKQTTQLEKLQAALREMGRLHPDFISVTFGAGGSSGGVST
VEVADFIQKELGVPALAHLICMGNDAAAAADILTRLEQAGVRDVLALRGDRSPTRPESPD
FAHASDLMAFIRDRKPGFALHGACYPEGHPESENLRRDVENLKYKQEAGAEHLITQLFFD
NMHFYRFLNLARRAGITLPVSAGVMPIVKRSQIERTVALSSASLPSDFTRMISRWQDDPA
ALYDAGIDYAVRQLRDLIEGGADGVHLYAMNDAAVAEKIYDGIRDLL
>A0A4R5BTL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora karakumensis|TrEMBL
MPFASTEEKVLAHVPRDVVLTVTTTEARGLEPTVDLAVRLGKNGYAAAPHLAARLVRDRA
ELDEIAARLLESGVDRLFVVGGDAAEPAGEFPDAESLLIALAEGGHDFSHIGIAGYPEGH
GTIPDSVISEALRRKTVHANEIVTQLCFNPATTIGWAGRLHDSGITTPVRVGIPGSVNRQ
KLIRVSAGLGLGQSARFLAKQSAMFWRFFLPSGYRPDKLVTGLTDQITSPGNAISGFHLF
TFNDLAGTERWRQARLAELA
>A0A317XLG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Testicularia cyperi|TrEMBL
MATYVAASSSSSSAAVAHPAHISTKIQNAVAEDQPFWSFEFFPPKTTQGLANLYNRIARM
KANLDPSWIHVTWGAGGTTGGKSLELAGRIQKGNLDPDVALVRKEVAQLGAGSKRLSQAT
GGETRDHDDQDACDVCLHLTCTNVEKSSLDETLEAAKRLGIRNILALRGDPPRGEEYWVA
ADDRFQHATDLVTYVRENHGDFFCIGVAGYPEGHADYVDRDLERDMRYLKAKQDAGAQFI
VTQLFYDVDQFLSWYRKCREIGITIPILPGIMPIQNYQSFRRMTNLCKAKVPQPILDALE
PIKSDDAAVKEYGVSLSIHMIGRIFLDSYQVPETTTWDEFPNGRYGDSRSPAFGEMDGYG
ISLKVPPQDALRIWGYPVTLQDISHIFASYLEEKIECIPWCDVPLMQETLLIRDHLLALN
RLGDADGTGKGTGKGWWSVGSQPAVDGAPSTDAVVGFGPPGGFVFQKSFVELFMSSSDKD
ELISRIEALGINSQVTYFAGNASGEFCSNLAEDEANTVTWAVFPGKEIVQSTIIEKESFE
AWREEAFGIWAEWELLFPKSSATRSLLESIKQDRWLVTVVHHDYKDTNALWNFLAQ
>W1TXC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Negativicoccus succinicivorans DORA_17_25|TrEMBL
MKIKDKYEKEGPLYSFEVFPPKREGDLGNMVATLHELAQWHPDYMSVTYGAAGAARGMLT
LKLAEYIRKELDIEPLMHLTCVGYSQAELAEILARIEAAGIENTLLLRGDRREDGETPAD
GFRYANELVAYVRSKHAFCIGAATYPEGHTEARSLTADLIRLRDKVNAGADFLVTQLFFD
NDAFFRFLETARSIDINVPISAGIMPCLNKAQIVRMTALSGASLPPKFRRMLDRYEHAPE
AMYDAGIAYACEQIIDLLSSGVDGIHLYVMNRPEVAQAITRGIGRTLQTVKEEHRGTNAG
>A0A397AFJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces astaci|TrEMBL
HRRTTDHNDGSSMKIIDKINEKIEKKEPFYSFEYFPPKTPAGVTNLYTRMDRMALMEPLF
CDMTWGAGGSTASMTIELCVNAQKLSGLEMLMHLTCTNMPKGSIKNALDSAKDAGIQNIL
ALRGDPPRGQTEFKECEGGFAYAIDLVKYIREEYGDYFCIAVAGYPEGHSDAKDLDTDIL
HLKEKVDAGADFIVTQLFYDVQKYFDFVDKCRAVGINVPILPGIMPIQNYNGFVRMSSMC
GHVPDAILQALEPIKDNDEAVKDYGVELGIQMCRDLLDHGVPGLHMYTLNLERSTRLILE
GLGLTATARRELPWRPSTLAKRAGETVRPIFWANRPKSYLDRTASWDEFPNGRWGSSESP
AFGDLNESYYSHTTASVQERKAMWGESPVTYADVYETFTRYVMGAVKSLPWCDTPLHLET
KSIQERLAAVNRAGYLTINSQPRVNAAPSDDPMFGWGGPGGHVYQKAYVECFVSPENLKR
IIEKCNKMKHVQYHAVDVNGNSYSNCGKGTTAVTWGSFPNKEILQPTIVDTDSFMAWKDE
AFSLWLSMWASLYHDESAAHALIHQIRDSFFLVSIVDNNFVNGDIWDAFDVDVTTASAAG
P
>A0A1C7NPJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Choanephora cucurbitarum|TrEMBL
MKVIDKINKAEQEGRPYWSFEYFPPKTAQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
DLTTEIVATAQSVYGLETMMHLTCTNMPKKQVDDALEAAKNCGCQNILALRGDPPKGQTN
WESCEEGFEHAIDLVRYIREKYGDYFCIAVAGHPEGHIDNPDKEDDLLQLKKKVDAGADL
VVTQLFFDVDAFLGFFKKARAIGISVPILPGVFPIQNYTGLKRVISFNNNFVPQKIWDDL
EAIKEDDTAVKEYGINLTVEFIKRFREVGINGFHIYTFNLERSSRLVLERLNLVAPVESI
KPLPWNPSLTTKRAKENVRPIFWKNRTKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
VNLKYSAEQCLQMWGSPVTIDDVSQTFAQYCKGQIAGIPWSAQQLDPETDVIRQRLAAIN
LLGYLTINSQPAVNGAKSSDPVYGWGPKNGYVFQKAYLEFFISPKKLDELLEKVGKDNQV
TYYAINKQGDLRTNTQSDEPNAVTWGVFPGKEVVQPTIVEAVAFTAWKDEAFELWNQWAR
IYERESQSAELILDISNNWYLINIVHNDFQDDNAIWRLFDLEIDGEISRKLLQSNTIAR
>B6EMP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliivibrio salmonicida (strain LFI1238)|TrEMBL
MAYSHASHLESLNQNIAELNGCINVSFEFFPPSSEKMEETLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLIAAPHLTCIDASRSELIDIANDYWANGIKDIVALRGD
IPAGGGAPDMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQASRFAKMNNVRIPGWMAQQFE
GLDDDPVTRQMVGASHAIDMTRILSREGVKDFHFYTLNRAEHTYALCHTLGVRPDVNR
>A0A1V1ZHE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mangrovimonas sp. DI 80|TrEMBL
MKVTDHIKQAKGKTLFSFEIIPPKKGSNIQELYNNIDPLMEFKPPFIDVTTSREEYVYID
RNGLLDRKITRMRPGTVGICASIKHKYNVDTVPHVLCGGFTKEETEYVLVDCHYLGIENV
MALRGDAMSHQKYFEPAKGGHTYASELVKQIQDLNEGKYLHDVIEADDRADFCIGVAGYP
EKHIEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNKRYFEFVKAAKEAGIDVPIIPGIKP
IAVKRHLQLLPQVFKIDLPEELISAVENSKDNKAVRQVGIEWAIQQSKELLEAGVPVLHY
YSMGKSDNIKAIAEHLF
>A0A5E7B4B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQRFG
EQVITEMCERLLEGGAPGLHFYTLNQAEASLAVWNNLKLPR
>C4IFK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium butyricum E4 str. BoNT E BL5262|TrEMBL
MIKEFLNNNILICDGAMGTYYSEKTGNDISYCEFGNLNDKNTIRRIHEEYIEAGAKLIRT
NTFSANSKELGVSRKTLKDIIESGIEIAKEAVYNKEVFIGASIGPIRENGADENFVEVLE
EYKFIVDCFLDNNINVFIFETLSNLDYLQEVSTYIKNKKPESFILTQFAVKPDGFTRDGY
SVSKIVGEVKKINTIDSYGFNCGSGPTHALELIKKIDIGDDIVSSLPNAGFPEIIHERTV
YPNNPVYFARKLKEIKKLGVSIIGGCCGTNPSYISKLRDTIDNKPEAGDKIKRYEHETYN
EKNIIKNTFKEKVKNGDFVIAVELSAPVDTDINKIMTGAKVCKDNNIDIVTVPDSPMSKV
RADSVVMSSKIKREIGIEAMPHMCCRDKNTNAIRSSLIGGHIEEIRNILAITGDPISDAS
RIETKSVFNLNSFKLIELINDMNNEVFTSDDIFIGGALNLNVLNKEVEYGRMMKKVERGA
KFFLTQPIYDDSAVEFLKSIKERTDVKILGGILPVVSYRNAMFLNNELPGVTIPQEILNR
FSEDMSREEGQNIGIDIAVSMGKKLKGICDGLYFITPFGRVNMIVDIVNRIKEV
>A0A7V9AQW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirales bacterium|TrEMBL
MSRGPRRLKEILDRGEFAVTIEYNPPKGTNISSIVESAKSLVGRVSGVNVTDNTAAVMRA
SSLSISRILYEMGHDPVMQMTCRDRNRLGIQSDLLGAHLLGIRNMLCLTGDYPTVGDHKD
AKPVYDLDSVQIMQVVQGLNNGRDLAGNKLDGPTDYMIGAAVTPEADPLGPMLAKFETKV
KAGAQFFQTQAIYHPEQFGSFMQAVRQFKVKVLPGVLLLRSAKMAEFMNANIPGISVPPE
MIEELRQAGEKHALDAGVEIAVRTIKSIRPYCDGVHIMAIKAIDRLPEILTKAELG
>E3E872|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus polymyxa (strain SC2)|TrEMBL
MKPDLRTVLNREIIVGDGAMGTFLSQLGFPVNTSYEELNITSPGVISDVHGQYLNAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
LELSRNYEQQIDALLSEGVDGILCETFYSLDEMRIALHSVRKYSDIPVICQFAVDQIGRT
QDGFLMAQAFSTLRSEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECATSFVDLGTRLIGGCCGTTPDHIAAISKALNNLQPPPLAPKETFS
TEVIHVVEQTADEGGRGNGRHTSEPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHALK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYIMTQPVYDPELIKAIAEQTRHLEIPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGPEGRAMGVSIAKELLDTAMEHFNGIYFMTP
FMFYEMTAELTSYVWQKSGRAQAPLFRL
>Q2RJ84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorella thermoacetica (strain ATCC 39073 / JCM 9320)|TrEMBL
MVESKMAKILSQGQFLVSGEIGPPKHADPTEIKKHAALLKDYVDAMNLTDNQTAIVRLSS
IAAGVHVLQAGGEPIIQMTVRDRNRIALQSDLLGAYSLGMRNVLCLSGDHQSFGNHPTAK
NVHDVDSLQLIRIVKDLRDEKKFACGEEIKGQEPRFFIGAAANPFADPFEFRVMRLEKKI
NAGADFIQTQCIFDMERFERFMALVRERGLHKRAKIIAGVMPLKSARAAKYMQQSVAGMI
VPDEIVNRMEKASDPKAEGVAICVEQIKHLQSIEGVAGVHIMAVMWEDIIPTIVKEAGLY
PRPKVE
>A0A1P8EGX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter soli|TrEMBL
MSSLASYFQQRQFCVLVEYLTSLTPYHPLQTEIAGYPTVMALADRVHSDHDLAPLDASRT
YDSAVEKLLHFSGKDRDIQDFEAFLAQAKAANIQNLLLLSGDKLKSHSDGTDGRPRTRYL
ESVNAVAAAQHVGGFHIGVALNPFKYVEAERDAQYLKLHKKLKAGADFIITQLGYDIKAL
QQAKAFLTSHDYAQKIVACVMPLTLARANYMIKHKVAGIVITPHMLNVLKHEKQTGQTAH
VYARCALQILICEQLGFAGVHLSACHKPDEQARLAEYIEEYRHLDLAALEQHYKRLWHIQ
TGLELQPERLPSARKPSRLEMMKYRHLQFMHDALFMSKPAKNAGRFIFKAAFWNTHLMTK
MLLKTESFSKHRLVGCESCGQCRLADTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVEQTQILKDKLIPTVPIATRGSSSWKNWYLAVEA
>A0A3M8DGJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus panacihumi|TrEMBL
MTATKLDLREYLQQHLLVGDGAMATQLHRLGVPVGISFEELCISNPKLVLEVHNSYCQAG
ARLLETNTFAANRDALARYGMEHRVTRINRQAVSLAREAAQGEAYVAGSIGSILAGRVRK
KVWDEYRDQYEEQAIALLHAGVDALLLETFLDLEELLLAIDVIRPLTNIPLITQLATLEV
GRTRDGYSLTDAFARLETAGADVIGLNCRLGPAEILRSFEQVQAPKGAVLSAFPNAGRLG
LTDGEYAYKSTADYFAESALRLREQGVRLIGGCCGTTPEHVRAMADALVALEPKERVNPT
IVPGERPQVTVTSIRDQDRPSIVEKVKNGTTIIVEFDPPRDLDAESFLEGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKSRYGLDPLLHLACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGISFSGRPLKQKAQFIVGAAFNPN
VRQIDAAIARLEKKVEAGADYIMTQPVYDAESIKLVYEATKHIGVPVFIGIMPLTSQRNA
EFLHNEVPGIKLSAEALERMKRVQGEEARQEGIKIAKELVDTAIRYFRGIYLITPFNYYA
MAAELIQYTRQQSELLKVPVQG
>A8MFK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkaliphilus oremlandii (strain OhILAs)|TrEMBL
MQIKELFKRKNLVFSFEVFPPKVTSPIGSIYDTLEGLQDLKPDYISVTYGAGGNGNDNRT
GEIAAIIKNKYGIEALAHLTCIGSTLEQTKGVLQELRDKGVHNVLALRGDIPEGFEGKGE
LKNSQDLIRLIREDQGNRFGIAAACYPEGHVEGKNVDQDIEILKLKEEAGADHAITQLFF
DNNYFYEFLNKVEEKGIQLPIQAGIMPVTNKKQIERIVALSGANLPVKFKKIMEKYEHNK
EALRDAGIAYALDQIVDLISTGARGIHLYTMNNPYIARSVTESIHSILKSVNKEKEVV
>A0A518GJB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctopirus ephydatiae|TrEMBL
MTVFTTPNALPSTNLSSLYTSGQFALSIEIFPPKTAEGDAALRQALQEFSTYNPAFVSCT
YGAGGSTRSRTLDWCREIIDRVGVAPTAHFTCVGSNSDELIEWLGQAWQLGVRNIMALRG
DVPQGETEFKAVEGGFSHARQLVELIRKEFPEMGIGVAGYPEKHPEAASLETDIAFLKEK
ITAGGHAVFTQLFYDNETFYRYWEMCLKQGIDAPIIPGVMPITEYSRVKRIVEISGTKVP
AELLEQLEAAHLRDDKAAQLEIGIEYSVQQCQDLIDHGVPGLHFYVLNKAHATSQILQSL
GLKNSEITTG
>A0A356E345|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerochaeta sp|TrEMBL
RQLSQFEPAYINVTNHQQEVVYLERPDGLLERRTVRKRPGTIALSALIQYTFNIPVVAHL
ICGGMDQDQLEDALVELNFLGIENVLALRGDPPNGEKRFVPVKGGYEHSSELVSQINDLN
MGRYLDQNLQNARKTHFCIGVAGYPEKHAEAPNLERDIEMLKHKVDSGAHYIVTQMFFDN
AVYYRFVDACRKAGITVPIIPGLKPIGSKRDLATIPQTFHVDFPSELVEQLTKATKLAEI
HEIGVHWCTLQTKDLLAHGAPSVHFYTLGKAESVASVVRSCY
>A0A1H8B7V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribius pelagius|TrEMBL
MTAPSISFEFFPPKSLEASFRLWDTIHTLAPLAPEFVSVTYGAGGTTRALTHEAVTTIGK
TTGLRVAAHLTCVNASKEETLEIARSYAAAGVTDLVALRGDMPGGKPFQPHPEGFANSVE
LIEALAATGDFTLRVGAYPDRHPEAATDTADVDWLKRKIDAGADAAITQFFFEADTFFRF
RDRCVAAGIDAPIIPGILPIENWAGVRKFATACGTPIPTWLDDAFETAKRDGREELLSTA
LATEMCSALLDDGVEHLHFYTLNKPQLTRDVVHALGLAPERQLEKVA
>A0A443LL84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinirhodobacter ferrireducens|TrEMBL
MTTPTVSFEFFPPQTLDASFRLWETVQALAPLKPGFVSVTYGAGGTTRKLTHEAVATIHK
NYGLNVAAHLTCVDATKAETLEIVDAYAEAGVTEIVALRGDPPKGAMHFTPHPEGFASSV
ELIEALAADGRFTIRCGAYPEPHPEATDALADVRWLKRKTEAGASSAITQFFFEADTFFR
FRDACVKEGITAKIIPGILPIQSWKGAKGFASRCGAAIPAGVAEGFEAAIAAGREREHAT
DLCIELCEALIAGGVEDLQFYTLNRPQMTQAVCAALGVVPAAAAA
>A0A2T0UXQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Knoellia remsis|TrEMBL
MTPRSIPGLLASERPSVSFEFFPPKDDASEAGLWDAIRRLERVHPDFVSVTYGAGGSTQD
RTVRVTERIARETTLTPLAHLTCVGASVADIRRVVGQYAAAGVRNILALRGDPPGDPGGE
WVAHPEGLDHATDLVALVRTLGDFTIGVAAFPDKHPASPDLDHDVEIMVKKADAGASFAV
TQMVFDADTYLRLRDRVAQRRDLPITPGLMPVTNLKQITRMAQLMGTPLPPAVVSRLEAA
SGSPEDVRAVGVEIATELAQRMLAEGAPGLHFITMNRSTATLEVHDNLGLSTGAR
>A0A257VWC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium 12-54-5|TrEMBL
MQPKITISQQLRELYGEAPPAVSFEFFPSKSAEAETKLWEVIGTLAPLKPRFVSVTYGAG
GSTRERTHATVTRIRRETNLTPAAHLTCVNATRDEIRDIAQTYWDAGVRHIVALRGDAPE
GAVYQPTPGGYGYADDLVKGLREVADFDISVAAYPETHPTARSAQDDLDHLKRKIDAGAT
RAITQFFFDVDVYLRFMDRVHAAGITAEIVPGILPVTNLAQVQKFSAMAGASVPDWLIKL
FDGLDNKPELRNLVAATVAAEQCRMLMLSGINHFHFYTLNRAELTQAICHILGLRA
>Q4FT38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4)|TrEMBL
MTKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVHALCA
RGDTDIAPHMSCIGDDKAEIAELLDLYKSLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFKLDVDNLVNKYQAGANSSITQFFYNADSYLYLR
DSLEKRGIDTVAQPLVAGIMPITNSSNLMRFADSCGADIPRYVRKQLADFGDDSKAIREF
GFDVVYRLCERLIAEGVPAIHFYSMNKVEPNKRLIEALGLA
>A0A0A8X8M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesobacillus selenatarsenatis SF-1|TrEMBL
MSFLKRLENEILIADGAIGTLLHSYGAGTCYEELNISHPDDIIRIHKAYISAGADLIQTN
TYAANYIKLERYGLEDQVKEINSAAVRLARQAAGTDAYVLGTIGGNRGIRPSAIPIEEIK
RSFREQLYCLLLEGVDGLLLETFYDMEEIESVLEIARKETDLPIIAQVSLQEIGIMQDQT
PLQEVFHRLEDLGADIVGLNCRLGPHHMISSLEQLELPSKAFLSVYPNAGLPAYTDGKFH
YEGNPEYFGKSAHSFRDQGVRLIGGCCGTTPEHIKAFADELKGLQPVLDKKISAKKPKIV
VTPADVKRPLAPLDQVVKERPSVIVELDSPRKLDTTRFFEGAKALKDTGIDALTLADNSL
ASPRISNGAIGHLVKEKIGLRPLVHLTCRDRNIIGLQSHLMGLHTLGLHDLLAVTGDPAR
VGDFPGASSVFDVSSFELIEMIKQFNEGLSYSGKDLGQKGAFSIGAAFNPNVRSIEKAVA
RMEKKIRAGADYFITQPVYSEKMLVEVHEATKHIDAPIYIGLMPLTSSRNAEFLHNEVPG
IKISQEILDIMAKFNNEPLQSKKEGIAITKGLIEAAAELFNGIYLITPFMNYEMSVELSS
YANEYSSRLMRRNQNVNLVN
>A0A849E7M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anderseniella sp|TrEMBL
LVDPSHLEDQIAAVAQIRELGLEPVPHVPARFVRNPDDLKSRIERLAVSGDVKRYLVLGG
GAPEPIGDYHCALQLMETGVFEANGAKALGVAGHPEGNADIAKLRGEAILMQALSEKQAY
ICDAGLEGFISTQFLFEAAPVASWAKALRDNGIDLPAFIGIPGPASIKTLAKYAAVCGVG
NSARFIRKQALNITKLLSVSTPDKFIEDLATLHASSPELKVMGPHMYPFGGFDKLFDWLS
TLPR
>A0A7C7QWP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibacterium sp|TrEMBL
EGSFKLWETLGVLAPLDPQFVSVTYGAGGTTRKLTHEAVSTIDANFGVPVAAHLTCVDAT
RTETLEIAEQYAKAGINQIVALRGDPPKGADGFSAHPDGFASSVELIEALAKTGKFDIRV
GAYPDPHPEAPSPQANVDYLKRKIDAGASSAITQFFFEAETFFRFRDACAAAGINAPILP
GILPIVDWPRARRFARACGAVIPTWLDDAYSAAIRDGREDLLSTAICTELCSDLIEGGVD
DLHFYTLNRPELTRNVCAALGVTSKAALAQVA
>A0A8B4GV06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. JKS000199|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLRDIATDYWNSGIRHIVALRGD
LPPGGGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A3A5H9N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides cavernaquae|TrEMBL
MTQGSNSIGARIRSGERSFSFEFFPPKDEAGEVQLWQAIRDLEAYAPTFVSVTYGAGGST
RDRTVDITGRIVRETSLLPMAHLTCVGHTKDDLDEILGAYASAGVTNVLALRGDPKEGPR
AEWTPTEGGFQHAVELVQLAASRGGFSVGVAAFPEGHPSAESLEHDAEVLVDKARAGAEF
AVTQMFFDASDYFALVERVREHGVDMPILPGIMPILNLNAIAKQGELIGTSVPAHVVDAF
AGLQEPADIRAKGIELAIQLCRDLLDGGAPGLHFYTLNRSKATREIFEALGLS
>A0A8G0WAB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerospermopsis torques-reginae ITEP-024|TrEMBL
MQDSHKTSTLNNFRKAVQAGEFLVTAEVAPPKGGNITHTIEMTATLKGRVHAVNITDGSR
AVLGMSPLAASAILLQHGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPDAKAVFDLESVRLLQLIRNMNEGVDFNHKTLNDGALDLFAGAAVDPQSKSWSGLQS
RFEKKIEAGAQFFQSQLITDFEKLEKFMDQIASRYNKPILAGIFLLKSAKNAQFINRMVP
GVNIPDHIIERLAKAKHPLQEGMKIAAEQVQMARGLCQGVHIMAVKKEEAIAQILDLAGV
EKVS
>A0A7W9APD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas yantingensis|TrEMBL
MVDASEALHPAWATMPAVVTDGYSLEMTAKDFDALHEAAPGIAPETPVAITFLPGETIDA
RVAAAAAVRRLGFEPMPHLSARRIGALGELDTMLGRAVDEAGARRAFIVAGDPPEPAGPF
ADTLSIIRTGLLEKHGFRAVGVAGHPEGHPNMAGEALWDALVAKLDALEERGLGSLIVTQ
FGFDADPFIDWLTELRARGIMAPVRIGVPGPAGIKTLLRFAARCGVGASAAVMTKYGVSI
TQLLGKAGPDRLVDALAARLTPAHGPVRLHFYPFGGLVNTVEWINGYPARTR
>A0A4Q2S903|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides ganghwensis|TrEMBL
MRNKRTAATLVRLLENARYEVLPTASTEDKVLEHLPRDRTVTVTASPTKGLEATLDLAER
LTGHGYVTVPHLAARMVSGRDELAEIAERLRGKGITSVFVPGGDAEAVGDYPDALALLED
LKELGSPFAHVGITGYPESHPTIHDDLTVQSMWDKRRYATHIVSNLTFDPAVVRDWVRRL
RARGVAMPLLLGIPGPVERAKLLGMATRIGVGESTKFLAKNKGVFARLAAPGGFTGERFL
ERCAPALGEEGALVEGLHVFTFNQIGETEAWRTGMLERLRTSR
>A0A1V6MQM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces phaeoluteigriseus|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFYAPKTSQGERSLWNALRRVEAVAPDFVSV
TYGAGGTTRATTVKETQQIVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSSDWDTDVARFVD
KCRAGADYAITQMFFDPESYLRLRDRVSAAGCATPVIPEVLPVTSVKMLERLPKLSNAHF
PAALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>R5X0J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. CAG:157|TrEMBL
MKVKEILAASDRTLISFELLPPLKGGDIGKVYNAIEPLMEFSPSFINLTYHRDEEVIRQR
PDGTLERITVTKRPGTVALAAAIMKRYDVEVVPHLVCGGLDRHTIENILIDLNFLDIDNV
MALRGDPAPGERFFTPTRGGHAYCSDLVRQISDMNRGVYLDELQQNPIPTHFCIGVAGYP
EKHYESPNLSQDIRNLKRKVDAGADYIVTQLFFDNARFFDFVERCRAEGITVPIIPGLKP
VSSLKHLEMLPRTFHIDMPEALTEELSRCRTDEQAKEVGIEWSVGQAKELKAAGVPAIHF
YTMSRSGNICEILKRVF
>A0A0D2ESS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala xenobiotica|TrEMBL
MDDRLPTLWSNLDPSSHYFSLEFFPPKTSSGFSNLQARLARMAKGLRPLFVTVTWGAGGS
TATKSLELAEVCQRQLGLTTVLHLTCTNMKRSMIDEALESAKEVGIRNILALRGDPPREE
YKDTDENGSGGQGTDSNQDFVWAVDLVRYIRRRYGDYFSVGVAGYPEGHADESVPEAGKQ
SVEHDLPYLVEKTAAGADFIMTQLTYDIQAYQAYEKMLRSYVDKDGKRVFEKIPIIPGLM
PAQSYSIIKRITKLSHAKIPEDILKRIEAVKSDDEAVKKVGVDILSELVEQMKELPQPES
VPRGFHFYTLNLEKSVAFILEKTGLIPPVTEQTSPTYSSDSDAVVDDEKRPGYSAHPPTD
GDHGRLPRLSKRRTSSINAQPHNRVILDGASGSPQGSRKAAPPSDSSTPMLTRHEAVERG
TGIPASEPTRKHNLMISEGQGSLGREATWDDFPNGRWGPSDSPAFGEIDGYGPSMKVGPI
TARKLWGHPKSEKDVTELFRRHVVGDLEAVPWSDEVDVDGDSSGGSGALRAETQVIRKEL
LALIQDKGYWTLASQPALDGVKSEDETFGWGPPGEGWVFQKAFVEFFCPRKHWEEHLKPL
LMRQGSTSLGWMKTDASGVFESSDEIEQENATETPTSKRTPGTSGINAVTWGAFRNREIV
TPTIIESESFRAWGEEAYSVWSVWRRCFPRGSDEEKFLDRMRQDLVLVNIVGNNYTGGHD
GHGGELWKILLEEK
>A0A7K2T926|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8352|TrEMBL
MALGTASIRTDRARTVRDMLATGKATFSFEFSAPKTPKGEKNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVAHFVD
KCRAGADYAITQMFFDPESYLRLRDRVVAAGCETPVIPEIMPVTSVRMLERLPRLSTAAF
PDELKERILAAREDAAAVRSMGIEFATEFSARLLAEGVPGLHFITLNSSTATLEIYENLG
LHQPPQV
>A0A6S7EGS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter anxifer|TrEMBL
MSDSISPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCEAAPHLSCVGATRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLNHFVNKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPLAVWKELSLQA
>B7GB47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeodactylum tricornutum (strain CCAP 1055/1)|TrEMBL
MSSSTPVTMSPEALSCVVPGTTPDPRIGDVIAQPRPDGKPFVSLEYFPPRTAEGVQNLHA
RMHRMRDTLQPAFTDMTWGAGGSTAELSLQLALYAHNTGHVANLHMTCTNLDSGKSSTST
SSSSEHNGNASDDVASADPRETLRRALQQAHDGGIRNLVALRGDPPAGQETWTATEGGFT
CALDLVEFIRSLPDIGADFHLAVAGYPEGHPNAISEIADPTTLTAAEAARASVTDGKTYC
CLDADYHKEMEYLKKKVDAGGDMIMTQMFFDAAVFLQFVEDCRAWGITVPIVPGLMCINA
YAGFVKMAKFCKTRVPETLRARMEAIKDDAAAVKAFGVEFGVEMCRTLLASGHVSVLHFY
TLNLEKVVYGVLDALG
>A0A5N8YFG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium AD-802-L14_MRT_200m|TrEMBL
MQPSGSASQHLSAMLENTDRFLTTVEIETSRGILMGEDSRKTKDSAQSLAEFDRVDFVSL
TDNPGGNPRIRPEVLGQELLSRGREVMINLSCKDYNRNSVESRLWALDSQGFSNVLALSG
DYPVGGFEGQAQPVFDIDSVGLIEMMAQMNEGLRNKALGSSSSGHRLEETNFFTGCVVSP
FKKLEGELMTQYFKLALKLRTGAKFAVTQIGYDSRKASEIHNYVESNGINVPLIGSVFIL
TAPAGRFFNRWGVPGVYVSDKLRDIAIRQAKSKDRGRLFFSELAAKQIAILRGIGYRGVY
ISGRPSLDRVQKILELADSYSQDDWREFAPEINFSQPGEFYYYEADENPGLSSSNINRDY
ISSRSKFARAKSRIGVPLQYRIGKFVHDRVFSEGSSGFKLGRSIYKQIEKSKKLSDVAHV
AEQVSKVPLYSCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTKA
>A0A7C1BSM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomicrobia archaeon|TrEMBL
MKRRSDEIYSDLMRELEEGRYVFTGELEPEKAGDVNEPIEMARELLDLVVACNVTDNPQS
FAYVSSLAASYQIQKETGMECVYQLRCADRNRMALLSDVLGAGVLGIKNILALAGDHVSL
GDTPDAKPVFDLDSTTLIKLIRTVVSEGKDLAGNEIHNPPKLHVGGAAAPGAAHLKAEVA
KVKRKIKAGVEYLQTQVVYFTDVLDKFFKELGPVDVPILVGIFPARTFGQADFFDKFVAG
VDVPPDYLENMRATKQIKDKEKRKEEVDRVNVEFFTGFLEHLKGTPAAGCHMMAVGYPRV
IPALKKIME
>A0A6G7T181|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ID38640|TrEMBL
MALGTASTRTDRAHTVRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVRHPDGVGYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVA
KCQAGADFAITQMFFYPEDYFRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A6N4ACQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 38-13|TrEMBL
MKVTEHIEKANGKSLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEYKE
LPSGLLEKKIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VVALRGDAVKNETYFKPEKEGNHYASELVTQIANLNNGIYLDDELQNSSATNFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGASYIITQMFFDNKKFFDFVAKCRKEGITVPIIPGLK
PISTKKQLNLVPHRFKVDIPDELIMSIVRAKDADAVKQIGIEWCISQSKELIKEGIPVLH
YYSMGKSENIKAIAREVF
>A0A7T7BKW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium digitatum|TrEMBL
MEKKITEKIAALPQDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKALGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRQTHGDYFCVGIAAYPEGHPADTFQDLQDPVRDIPY
LVEKTLAGADFIMTQLTYDIEAYQKFENTLRNHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIARRMEELKHDDEAVKRAGVDIVSEIVGGIRDIPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPSYSDAGDLAIEDDPASIPLDFPGRALRRRRASSINSQPHNRVVVDKL
SVHGSSQDSVHEARADSAGVPAPPPSRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTANSARRLWGHPVDSKDMSTIFRRHVSGELHMVPWSEGGAEEDGEG
LNAETELIRPELLKLIDGRGWWTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFC
SSNDYTNILKPMFAKHGHDKLTWFATNIKGDFESSLPIQPADVELDDLGSNPESVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTEAYLDTTKNDSWLVCVV
GQQFGAGTKQGSKEEEDEVKWMWRVLAGEEV
>A0A101NBG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces pseudovenezuelae|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTHSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNILAVR
GDPPGDPMGDWLAHPQGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVHAADCETPVIPEVMPVTSVRMLERLPQLSNASI
PSALEERILTAKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHRPQA
>A0A6C6ZQK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella heidelberg (strain SL476)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1Q2HT83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium glaucum|TrEMBL
MRGNFASTRLSASAPLDSPFEVDQYSPVVKHHGTRTALSFELIPPRNSTDSAKLDELIQG
LAAYHPDYVSVTSSMRSDWLAGTTALIERIASTTDLRPIAHLACTAGPKVELEGWIRQLI
DVGVRGFLALRGDLQPGQTSLPEGYLPYATDLLNLINKVQEEEAFRLAAGKLALSVACYP
SGHAESKHFDHDLDVLLAKQRLGADFAITQLFFDASDYLEFVEVARLAGVRIPLIPGIMP
ITSLARAKRMGELSGLQVPETVEKRLASATSPEEEYELGMELSAELTRTILDAGTGGLHV
YTHNNLAVTRDLLGRVGIQQP
>V4PL92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asticcacaulis sp. AC466|TrEMBL
MSPTLNPALKPELAPIARSLAAGGQNLKVSFEFFPPKTEEMETTLWESIRRLAPLNPDFV
SVTYGAGGSTRERTHRTVKRMLDQTELKPAAHLTCVDASRDEVDEVIRGYWEAGVRHIVA
LRGDPPSGFGDYVPRADGYQNATELTAAIRRIGDFEVSVGVYPEKHPQSPSLAFDLDVLR
QKVDAGATRGISQFFFEPATFLRFRDAVADAGIQIDLTPGIMPVTNFKGLRRMAAACDAH
IPAWLAALFDGLDDDAETRKLLASAVAVELCLGLEREGVENFHFYTLNRADLVFAICRIL
GIAVAAP
>A0A2M9FZZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Minwuia thermotolerans|TrEMBL
MTEMFRLGGSPRIGASIEATPTQVLEKVDLAGLFPVNTRVYLTDLGTDDSARLIRAARSL
QDYGYVAVPHLAARRFTSWAAFEARIQALAGEAGVTEALAVAGSPERQAGPIAASIELLR
SGWFDRLGFTRIGVAGHPEGSPDIAPEALDAALREKNAFAAETDAELYLVTQFGFDARRF
IAWAERVSAAGNRLPIHIGVSGPAKIATLLKYAAACGVGESLGFLKKRAGAVTALATGHS
PESVVQPLESYWAGDPAGPIRQMHVFPFGGLKKSSQWLFERGSWVNGVEAFADTQPIQLE
ARK
>A0A2T5LBZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. OK519|TrEMBL
MTFDAVRGRSSAGFVTQTPSIVDRIRSSESSKTGRIPFSVEFSPPRDEAAEARLWRAVRE
FERLGPAFVSMTYGAGGSTRDRTVRVTGQLAEDTTLLPVAHLTAVGHSIDELRSMCGAYA
DRGISNILVLRGDPPGDPLGEWVKHPDGVEYAEELVRLVRDMGDFHVGVASFPEGHYRAP
DLDHDTKYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVSLLDPEQGAKPIIPEIMPITSL
RSARRSLELSGSSLPPVLEERLTRAAGDGPEENRAAVREIGIEVATEMSERLIAEGAPCL
HFITLNFARATGEVLANLGMSASAAV
>A0A550JIY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas acetexigens|TrEMBL
MSSANDRSRRFLEELGRRLIIGDGAMGTLLYSRGVRLDTNFECLNLHAPELIRQVHEEYL
AAGSRLLETNTFGANAPRLAGFGLDGQARAINLAGARLAREAAGDDAYVAGSVGPLQRPR
GEGGVLSREEAEAALREQMEALAEGGVDLFILETFADLADLELGVAIAHELGLPVVAQMA
FLQEGRTRDGISAEDAARRLTAAGATMIGANCGAGPRELLQVVTRMAAVSVLPLSAFPNS
GFPEYVEGRYIYLATPEYFAGMGRELAQAGAVLIGGCCGTTPEHIRALTEALATLVPAPT
TRVVLTPDLSTPTVTPPPESRSDFLADWGRRPIVTVELDPPRGLNCSKVLDGARALARVG
VDAISLAENPLGRIRLGNIALARAIQEETGTEVIVHVTCRDRNLIGLHSELMGAHLLGIR
NILAVTGDPVAVGGESGATNVFDLNSVSLLELLTALNDGHNLLGAELDGRTRFLLGAAFN
PNLTTMEGQLRKLGKKVAAGARFVQTQPVYSTRVLDELLEKTAPFGVPVLVGILPLVSER
NAEFLHNEVPGITLPEAVRERMRGKQGEAGVREGMAIARELIEAGRGRCGGYYLMPPFGK
VELALELMAFIRRTAG
>A0A811MJK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Miscanthus lutarioriparius|TrEMBL
MKVIEKIQEAAGNGRTAFSFEFLPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCINMPVEKIDHALETIKSNGIQNVLALRGDPPRGQDK
FVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDVKQGEGGATLEAYSNDLAYLK
RKVDAGADLIVTQLFYDTDILLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPSEITAALDPIKDNEEAVKQYGIHLGTEMCKKILASGIKTLHLYTKNMDKSALGILMNL
GLIEESKVSRPLPWRPATNVFRVKEDVRPIFWANRPKSYLKRTLGWDQYPHGRWGDSRNP
SYGALTDHQFTRPRGRGKKLQEEWAVPLKSVEDISERFANFCQGKLTSSSWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGDKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLD
QLIKKIKAFPSLTYIAVNKDGESFSNIATNAVNAVTWGVFPGKEIIQPTVVDPASFMVWK
DEAFEIWTRGWACLFPEGDSSRELLEKVQKSYYLVSLVDNDYVQGDLFAAFKI
>A0A5J5G8W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus spiritus|TrEMBL
MKPDLRKAWESGILVGDGAMGTFLYNMGFPVGISYEELNLTRPEVIRDVHRSYMEAGAQV
LESNTYSANEDKLSKFGLESGVEAINRAGVRIAREAAGETGYVVGAVGSIRAGKRANLSA
AELKRLFGRQIGALLEEEPDGILLETFYDVEELHLALRTVRKLSALPVICQLAVDETAMT
LDGLTLPEAFRILQEDGADMIGFNCRTGPIGIKRSLGTLQGQLEVPVSVYPNAGVADYVD
GQYRYGASPEYFGSMATAFADLGARLIGGCCGTTPAHIAEIAAALTDYEPRPLPEPAASP
ERDRIRIQEPAEEEGGDGGEPTLVDLVRERHTVIVELDPPRDLDISRFLDGAEALRRAGA
DALTLADNSLAVTRMSNMALGAIALQKTGLRPLIHIACRDRNLIGTQSHLMGFDALGIDH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGISFSGKPLKQRANFVIGAAFNP
NVKHLNKAVERLEKKIASGADYIMTQPVYDPELIGRIADATAHLNVPIFLGIMPLASGRN
AEYLHNEVPGIQLSDEVRRRMAGLEGEAGRAEGVAIAKELLDEAMKRFNGIYLMTPFMFY
EMSAELLQHVWTKTGRRLSPLFR
>A0A133Q7P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus lugdunensis|TrEMBL
MSQFLNQLQNNILVADGAIGTILYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKPFGLEHKVKEIHKAAVKIAKRAATKNTFILGTVGGFRGIKQDDISLSTI
QYHTENQIDTLIEEGVDALLFETYYDLDELKRIVTWTKRNYDIPVVAQLTASNTTYLVDG
TEINDALAQLVTCGADVVGLNCHHGPHHMEKSFSHIALPDNAYLSCYPNASLLDIENSEF
KYSDNAQYFGAVAEKLIEQGVRLIGGCCGTTPQHIHYIKSSVSHLSPVNHKKVIPIHKKS
NQRRTDSIKQSLTSKVKQGPTVIVELDTPKHLDTDLFFENIGKLDAAHIDAVTLADNSLA
TVRISNIAAASLIKQRYDIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGSTNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKIASGMSYFITQPVYSKEKIIQVYEATKHLNIPIFIGIMPIASYNNALFLHNEVPGI
KMSESVLNQFKAVKDDKEKTKELSLRLSKDLIDTVHQYFNGLYIITPFQRVDYSLELAAY
SRSITTNKEAIL
>A0A2M7SGU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_10_14_0_8_um_filter_43_12|TrEMBL
MNNSSKLKRVLEGGGFAVTAECGPPKGANPDVVLKKAEMLRNKVDAVNVTDNQTAIVRMS
SIAACSLLKTAGLDPVLQMVVRDRNRIALQSDILGASALGIRNVLCLSGDHHIFGNQPQA
MGVFDLDSIQFVQVVRTMRDEGKILGGDGLSQPPDFFIGAAANPFADPFDFRVIRLAKKI
RAGADFIQTQCIYNLDRFERWIGMARDRGITDKAYILGGVTPLKSPGMAKYMKNKVSGMD
IPDEIIKRMEGVPKDKQREEGINICVETIQRLRGVPGIKGVHIMAIEWEEVVGEIVERAG
LLPRPVFD
>A0A1X7P5N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter oskolensis|TrEMBL
MSRVRFEIIPSDDIAERAERAFPDPAGVTLTITSLPQHGTERTVDTALELAARGFGVVPH
LAARNVSGRSELERILGRLREAGVDEAFVVSGDAKNAAGSYSTSLELIRDAVEISPGLAL
DIAGYPEGHPHLSDESIARHLRERAPFIRGIVTQMCFDVDAVVRYAEGLRPQGIAAPVWA
GVPGPVERTRLLTLGARIGVGASLGFLSRNSSVAGGLLRGRRFDPTAFVRRLEAAAGDRL
HGLHVYTFNELDGLDAFGS
>A0A1H9E0Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium frigoris|TrEMBL
MKVTEHIAAAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMDFKPPFIDVTTSREEFIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGINN
VMALRGDAMKDEQSFVAKAGGNNYAVDLVQQINLLNEGKYLHDVMHVDNKADFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNVKYFEFVAKAREMGITVPIIPGIK
PLAVQRHLQILPQIFRIDLPEDLIDAVDKCKTNTDVKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKIF
>A0A370DTU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|endosymbiont of Escarpia spicata|TrEMBL
MTTNRSFSFELFPPKTEKGFENLKTAVNQLNALNPEFFSVTYGAGGSTQDRTFASVDWLR
EQQIETAPHLSCIGSSREEILQILDRYHEQKIRRLVALRGDLPSGAGLGSLGELNYANEL
VEMIKERYGDHFYIEVAAYPEFHPQANSAKADLKNFKRKVEAGADGAITQYFYNPDAYFC
FVEECSDMGIDIPIVPGIMPITNYVQLARFSDACGAEIPRWVRRRLESFGDDLEGIRAFG
AEVVTELCRRLLDGGAPGLHFYTMNQATPTLKIWNNLGL
>A0A093ZHB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4246|TrEMBL
MADSPTTDKITDKIAALPQDANYFSLEFFPPKTAMGSTNLRARLDRMARALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSRALVDQALSAAKEAGIQNILALRGD
EPRGEYKDALEEGKDGEDEFVWAIDLVKYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
VHDLPYLVDKVQAGADFIMTQLFYDVDAYDNFEKVLRDHSSGTFKTIPIIPGLMPIQSYQ
ILRRTTKLSNARLPESIINRLDAVRSDDEMVKRVGVDILAEIVESVKHTKSRTKGPKGFH
FYTLNLEKAVAFILERANLIPSFTPVLTSDVFAVDDITDTIPLPQLLINGEKKTRRQSSV
GSGPHNFVIIDREEASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRSDISSIFVQYLSGNLSALPWSDE
PITAETNLIKNELVKLNQKGWWTIASQPAVNGERSQDGVVGWGPKGGWVFQKAFVELFVP
TSDWARLKPLLESNEEVSFLAQSASGEFLKSKLDLGPGEEGSETNAVTWGVFPGKEIVSP
TIVEEVSFRAWAEEAWQMWAEWAAVFGKSGEESRRFLDGVSRDGWLVNVIWHDFVGMCKA
KEGRSEEPGYKGLWDVLIEA
>A0A250L0Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocaldum marinum|TrEMBL
METQKKYPKIFSLEFFPPKNHEAEDTFRTNLAKLAALKPKFCSVTFGAGGTTREKTFETV
IEIQRNTGIEAAPHISCIASTKASVREVLDAYKNQGIRHIVALRGDMPSGMLSPGEFRYA
NELVEFIRRETGDHFHIEVAAYPEMHPQAANMEADLRNFKRKVEAGADSVITQYFYNPEA
YFRFVDDCEKMGIDIPIVPGIMPISNYTQLARFSDACGADIPRWIRKRLEVFGDDRKSIR
AFGLEVVTDLCRRLLEQGAPGLHFYTLNRAEAVLGIWRNLGIAAD
>E4U7S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanithermus profundus (strain DSM 14977 / NBRC 100410 / VKM B-2274 / 506)|TrEMBL
MRLTDKLGHGFVLTAEVDPPRGADPAPTLKQALILRGYVDAVNVSDAPMANLRMNSIMLA
HLIQHHTGVEVIPHLTARDRNVIALQADLLGAWALGVKNVLVLGGDPPERGDHPRARPVY
EFGAVGLVETIARLNRGENLSGGSLEGAPDLTAGVAVNPGAADLAAEAEKFWAKVEAGAR
FAQSQPVFCPETAAAFLDALGGKSPVPILWGVLPLRSVKMARNVARWTRVPEALVADLER
EGRAAGMRAAQDVLRALHAAGMDGAHLYPLGRVELLKEMLKPLGARLG
>A0A7W0WGX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacteraceae bacterium|TrEMBL
MSPNLRELLATRVLIGDGAVGTLLGERGVGFGHPYARANLSHPEMVTDIHVEYLRAGADV
IETNTFAANRFKLETHDLEERVREVNAEGASLARKAAYTVAGTGDRALVLGAIGPLGRPL
APVGPVSPERAKSVFLEQAEALLEGGADAILLETFTDLVELRLAYEAVGALGAPVLAYKT
FVEDGETLAEGLPGRAAREISSWGADLAGANCTVGPQRMVEIIGQMADAAGPVAALPNPG
LPQIVGGHIRFSKGVDHFAEYGIKLAEAGARLVGGCCGTTPAHVKALSEALQDFRVEGKR
TRRRGSVAERTWLTEVSVEPVSEFAERLRAGFAVTVEVDLPRGNAIEQVVEAARRLKERG
VHAIDISDGARARLRMHPVAAARIVQDEAGIEVVAHISCRDRNIIGLQADLLGAAALGVK
NILAVTGDPAQIGDYPEATSVFDTDSVGLVHILSRMNRGEDLAGNPIGEPPGFLVGASFN
PTAEDLDEEVEKLRRKVEAGAHAFWTQPVFEIGGLENALERIGVDGVCILLGLMPLRSAR
QAEFLHHEVPGIDIPKHVREKLAALSPEDAPKYGVEVAQELLIAARPLIGGAYIMPPASA
PDLAGDVLEAISLPAGR
>A0A354BXH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSGIKPARRWQPAFYPFKREKLSRRILAKTEILIKGPLFGCRMCGNCLLQETAFICPMEC
PKGMRNGPCGGITPEKNCYIDETRKCVWYAIYKRALKTGRQEMLLEILPPLDWDKVGTET
WGEVARQIRKVGTGKFVRSLFPHNKKDKSAIWDSVFKTIRQPDWWQGDSEYHAPASDKPV
SNLEKKLKSGEFVVATEVTPPLGASTGSLKRDIESVRPFVAAINFTDSSYARPRMSSIAC
SKIAVDLGAEPVLQITSRDTTRSGLQGDVIGINGLGIYNVLCISGDSPRVGPTPTGSMNF
VDLDSVQMLWILRRMRDEGTYLDGRKMKENPKLFLGAATSPFASDPELQAIKDTKKVNAG
AQFFQTNLIFEPDRIDPWLEQLYRRNILDKVYILIGLAPLKSYKVAQYLHTKVPGVSLPA
HILNRMEKAGESAPEEGVQIALELIDGIKKKHGVHGIHIMTLGWESIVERIVTESGLLP
>A0A6C0G391|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus lycopersici|TrEMBL
MKPDLRETLRTRILTGDGAMGTYLYGMGFPVGVSYEEFNLLRPEVIADVHRRYYEAGARI
IETNTFSANLASLTNYGLDNEVEAVNRAGVRIARSAVGSDAFVVGAVGSIRAGKRKNMST
GKLERLFRQQIDALLTEGVDGILLETFYDLEEALIALRIVRGLSGTPVICQFAVEKEAVL
IDGQPVETAFERLRLEGADVVGFNCRSGPNGILRAIDTLSGDLRLPLSVYPNAGIPDYVD
GKYIYGTTPEYFAQYARTFADRGARIIGGCCGTTPEHIAAIAAALDGYVPQPAAAVDPAE
PEQPARTERIVVQDREARKREAENAEATIVDLVKRRHTVIVELDPPRDLDIQKFMDGAKA
LRAVKADAVTMADNSLAVTRMSNIALAALVQEQVGIRPLVHIACRDRNLIGTQSHMMGLD
ALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGMAFSGKPLKQKANFIT
GAAFNPNVKYLDKAIARLEKKIDTGADYIMTQPVYDKELIVRIAEATKHLQVPIFIGIMP
LASGRNAEYLHNEVPGIQLSDDVRKRMAGLEGEAGRAEGVRIAEELLDTAMDCFKGIYLI
TPFMFYGMTVKLTEYVWRKTGSLTI
>A0A7X9I9G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSGIKPNRRWQPAFYPFRKERFGKRLLARTELLIKGPLFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGITPDKKCYVDQTRKCVWYCIYDRAKRTGRENMLLEVLPPLDWNKTGSET
WGDVVRQITKVGTGKFFSSLLLKDKQLKSKIWDSVFKTIRQPEWWKGDAEFHPPLYGEPV
SELERKLRSGEFVVVTEVTPPLSSNAEKLKENLTLVKHHVAAVNFTDASSSVPRMSGIAC
CRTATDLGIEPVFQIAARDTTRTGLQSTAVGLNNLGIKNILCITGDNPIIGPHPVADLSM
LDLDSVQMIWILRRMRDEGVYLDGRKMKYPPRYFLGAATSPFASDPGLQAIKDQKKVNAG
AQFFQTNLIFEPDRLDAWLENLEKRNVLDKVYILAGVAPLKSYKAALYLHEKVPGVTLPE
KILKRMEKAGEKSSGEGVLIALELIDAIKRKKGISGIHLMTLGWEEIVERIVTESGLSGK
>A0A3D0DFH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium|TrEMBL
MAIDLREKLDAGVLICDGAMGTYLNQKGISYDRCFDELNISAPQVVGEVHREYIEAGAEI
IETNTFGGNRFRLAAHGLEQKFRDINLQGAKIAREAREVSGVDLLIAGSMGPLGKPLEPI
GKIKLHDAQLAFTEQAEALLEGGIDLFMIETISSLDETEIAIAAIRQICDLPIVAQMTFT
AEGSTYLGHTPAEMVARLLPLKVDVLGANCSVGPQKMLEVIEQLSELGVGYISAQPNAGL
PRYYGGRFIYLSSPDYFAEYAKSFVKAGALIVGGCCGTTPAHISAVAKAIKGTGITRQLS
SIKVKSSAEAMIVEPFGGAKTRLYEKLKNNFAISVEIDPPKGTNPAKLIEAAIKIKEAGA
DAVNVADSPMARVRMSCLALAYLISSSVDIDIVLHFTTRDRNLMGLQADLIGANAVGIHN
ILALTGDPPSIGDYPQATAVYDVDSIGLVRIISRLNSGMDLAGNSIGKPTALSIGVGVNP
TVPNQELELRRLREKLDAGGQYIMTQPLYELDLLKHFIDKFKPNVPILLGVLPLVSFKHA
QFLHNEVPGISVPTRTCQMMEKAGERSAQVGGELAAEFIEQAKGYVTGVYLMPSFGRFET
CIELVRYIRGN
>A0A7X9JQ16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
RDLLDKVYILAGISPLKSYKIARYLHDKVPGVFLPKDILTRMEKAGDGASEEGFQIALEL
IDSIKSKKGIHGIHLMTMGWEEIVGRLVAESGILQQ
>A0A2E8Q202|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium|TrEMBL
MESFKEALKNKFLVCDGAMGTALYSKGIFINRCFDELNLTNPDLIREIHSEYIKSGADII
ETNSFGANRFKLQRYGLDSKVYDINKASAVIAKDEARGGVFVAGAIGPIGGGIEPLGKLS
KLKAKEAFIEQAKGLLDGGVDLFILETFSDLNELHQAYFAIRELCTKNAVEKPIITQITF
EDDGNTFYGVSPVRAVKEMESWGTDAAGANCSIGPQPMFESIXKMAASCSIPLSVMPNAG
LPRIVEGRQIYLSTPEYFATYAKRFIRSGVRIVGGCCGTTAEHIKLICSAVKAISPSRIE
ITETAKSDKTPKTITPLLTAQKSDLAKKLSXNKFVVSVELLPPKGCDPSKVLEAAKKLKE
AGVDNSNIPDGPRASARMSSMSLAGLFLREVGIEPIVHYTCRDRNLLGMQSDILGAEAAG
IKNILAVTGDPPKLGNYPDATAVYDVDAIGXVKLINNLNHGLDVAKNPIGKPAGIHIGVG
VNPGAINIEEEERRFRQKVEAGAEFVLTQPVFEEKLFFNFLERNKDLNIPIXLGVLPLXS
YRSAEFLHNEVPGMSIPENIRKRMKKADAANKAKETGXEIAREAFLKMKDKANGAYIMAP
VGGVDTALKALKGLI
>A0A448BF40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus milleri|TrEMBL
MSSPSPSLSFEVFPPNPAVGNEKIMAALKEMQDLVPHFISVTASNNKFNIEETTVRLADF
IRNDLHIPTIAHLPAVYLTKEMVTETLTALDKVGVHKVLALRGDILPDVEPQKDFVYATD
LIEYIKKEAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYD
FQDKCILAGIEVPIHAGIMPILN
>U5QH61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gloeobacter kilaueensis JS1|TrEMBL
MAQTTRLEKAIAGKAFLITAEVMPPKGPDMVAFIEKASLLKDRVHAINVTDSNRAVMRMS
PLAASALLVQVGLEPICQLACRDRNRIALQGDLIGAEALGIHNILALTGDPVDCGDHPRA
RAVCDLESVRLLQVIDGLNRGVDSAGNALNAQTHLFAGAAIDPQSGSESGLRSRFRRKVE
AGARFFQSQLITDFKRLGWFMDNIACEYERPVLAGVFLLKSAKNALYINRNLPGVTIPEA
IIERLERAGAQAQQEGIVIAAEQVAAARQICDGVHLMAIRREEVIPEILDRAGVAALTSF
>A0A1F4BHS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_67_26|TrEMBL
MESQRKHPRTFSFEFFPPKTAEGKQKLRATWKQLGQLKPKFFSCTFGAGGSTREGTLDTV
LEIRAAGFEAAPHISCVASSRADLGVQLEKYQSHGIRHVVALRGDLPSGLAAIGELRYAN
ELVALIRETTGDWFHIEVACYPEYHPQTRSAADEIRNFKRKVDAGANSAITQYFYNADAY
FRFVDDCEAAGITIPIVPGVMPIGNFAQLARFSDACGAEIPRWLRFKMESFRDDTAAIRS
YGLDVVTRLCDDLLSAGAPGLHFYTLNQAGLTTTIWQRLGL
>A0A0W0FF57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moniliophthora roreri|TrEMBL
MKLSEKISTYPSSHPFYTFEFFPPRTDQGFENLLPRIARLSKLSPLAISITWGAGGSTKD
RSLDLASMTQGEGTETILHLTCTNMMQGMVDDALRAAKDRGIQNVLALRGGERLTDPPRG
KEEWIPIDPRFQHGVDLVSYIRSKGEFKDHFCIGVAAYPDGHPDKLVSPEAELDSLKAKV
DAGADFIITQLFYDTENFLEWSTNGDSYAGITLPIIPGIMPIQTYSSFLRLVKLCGSSVP
SKILEDLEVIKYDDQLVKDYGVQLAISMIQHIAQSDAGVKGVHFCTLNLEKSVTRVLEGL
QWTGTRPYAYHHNRLIESSTDLTEHTINPSTALSTALSGTREIPKSQHEAGTGELNNADS
WDDFPNGRFGDHKSPAWALGEGDLWGNLGLIITNKTLESWGPPQTPDDLTNLFLKHLRGK
IHTTPFSPSPLSAESQSILPYLEKLTRKGLWTVGSQPAVDGIHSDDPIVGWGPRGGYVYQ
KAFVEFFCDADGVDEIEKKVEEKGGGWVSWFAGSFSGEIRSNMPEDGRNAVTWGVFPGQE
IVQTTTIEKEGFGSWKEEAFSIWLKWASYYPPQSAERALLDKVRREKWLVSVVHHDYKDK
DALWEFLFDD
>A0A2N8AY43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FW306-2-2C-D06C|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A5C4INA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. NamE5|TrEMBL
MMSPLRIEIIPAPGIVEQVKALVPRTITLSVTCLPHHGLERTVRTAVELSDGGYTVVPHL
AARSIGNRAELTGIVRGCDAAGIREVFVIGGDRKQPAGAYDSALPVLEDIAQYTGGLMRA
GVAGYPEGHPLVSPVDLLDGLLAKQHLATHVVTQMCFSADTIHHYAALLRHEGLNLPVWA
GVAGPVPRTKLVALATQIGVGSSLKFLSRKGPLARKLLSGDRYSPDSLITELGSQPGKLA
GVHLYSFNSLDSIPGLPKSEEPGNTSTTAALQPTSIRGAARDH
>A0A5C4IYZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. NamE5|TrEMBL
MSPPSLIDTHPNLSDTAPVALSYELFPPRSPAAAETLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIIGELLDTGVRGILALRGDLPKD
GGEPVPGALRYAQDLIELVRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFRAEQYADLLTRARRAGVTIPIIPGVMPLTSLRRLKRLGELAGVE
PAPELMERLGAADSDLDRLHIGVNATVDLANAALEAGAPGIHLYTFNEHQSALEVLDKLA
LPRRIHASSGRNIAARQLAG
>A0A2M7NKH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flexibacter sp. CG_4_10_14_3_um_filter_32_15|TrEMBL
MKVIEHLNANKGKTLFSFELIPPLKGESIQSIFDAMNPLMEFNPPFVDVTYHREEYVYKT
RGEGLLEKKVTRKRPGTVGICAAIMNRYQVDAVPHIICGGFSKEETENALIDLSFLGIEN
VLALRGDAVKSEGSFIPEKDGHNYAVDLIGQIVDMNKGNYIDDDLHHPIPTNFCIGVAGY
PEKHFEAPNLNSDMLALKAKVDAGAEYIVTQMFFDNSKYFEFVDKCREFGINVPIIPGLK
PFTTKKQLSVLPRIFHIDIPDDLVAAVFACQDNKAVVQVGIEWAVQQSKELMEKGVPCLH
YYTMGRSGATEKIAAQLF
>A0A4Y8I324|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium MT.SAG.1|TrEMBL
MNLREKLAAKKFAVTVELDPPKNVNLSKILSEVNDDNFRKVVDAVNVTDCPMAKLRMGPI
ALSHIIQERIGLEAIFHITCRDRNLLGLQAELLGASALGVKNILALTGDPPKMGDYAMAT
GVYDVDSIGLVKMVNKLNNGYEYGENELKDKTDFFIGIAVNPTAQDSKKEIARFEEKVSA
GANFVQTQPIYDVKSLEKFLKMTDHINIPKIIGIMPLKSYKMVEYLNNNLPGIFVPPGVK
ERMRGKDIEEGIQISRELIDKINKYKEVAGIHIFPLRDMDLVCRLFN
>A0A8C6V0J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neogobius melanostomus|TrEMBL
MVNQVQRGDGTLSSRSDSSAASASGGDSSKESSRCSTPVLDADRTDRLRYKMRRRMESGD
HWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPSGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQSKDNISRHLSKAKHLGLKNIMALRGDPVGSDWEEEEEGFNYAVD
LVKHIRSEFDDYFDICVAGYPTGHPEAHSYKEDLIYLKEKVAAGADFVITQLFFRAETFL
KFEEDCRPSGSPCVCVQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIHQAL
EMCRVLLDSGRVPGLHFYTLNREVATMEVLRQLGMWQEDPRRPMPWAVSAHPKRKVEDVR
PIFWGSRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLQMWGR
SCTTNGCDVVLQVMCLPWNDEPLAPETNMLKDELEKVNTRGVLTINSQPNINGKPSTDPI
VGWGPPGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPN
AVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYF
LVNLVDNDFPLDSCLWQVIEDMFELLQTGLDTGDVLGALNTGDGGASGGR
>A0A7L4LC55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callaeas wilsoni|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTRDDITGHLQKAKRLGLKNIMALRGDPTGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAMGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A8C6UUH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neogobius melanostomus|TrEMBL
MVNQVQRGDGTLSSRSDSSAASASGGDSSKESSRCSTPVLDADRTDRLRYKMRRRMESGD
HWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPSGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQSKDNISRHLSKAKHLGLKNIMALRGDPVGSDWEEEEEGFNYAVD
LVKHIRSEFDDYFDICVAGYPTGHPEAHSYKEDLIYLKEKVAAGADFVITQLFFRAETFL
KGVYAYLDQQCVCVQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIHQALEM
CRVLLDSGRVPGLHFYTLNREVATMEVLRQLGMWQEDPRRPMPWAVSAHPKRKVEDVRPI
FWGSRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLVFEVFTC
YIAAQPNRKGHKVMCLPWNDEPLAPETNMLKDELEKVNTRGVLTINSQPNINGKPSTDPI
VGWGPPGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPN
AVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYF
LVNLVDNDFPLDSCLWQVIEDMFELLQTGLDTGDLEATKLFHVFPI
>A0A7W4LIS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas ullengensis|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVKVPTAPHLSCVGDSKDDLRSLLQQYQSSGIKRIVALRGDLPSGMGMASGEMRYANEL
VEFIRSETGDHFHIEVAAYPEVHPQARNFEDDLANFVRKAKAGADSAITQYFFSADCYFY
FVERVRKLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDLQSIQAYG
EQVVSEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A855SIL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium angustum|TrEMBL
MSDQYQPTPESELRVRYNDITRGVYFIGTTPPKTSTPIEDVEGIADRLVDRIRDLAIDGL
IVYDIQDEASRTNKPRPFPFKSTHDPRHYSSLLNKKTDRPVITYKSVVQSETEAFDEWLN
EAWDEYRVRDMVLVGSPSAKNDVSLPLSKAYQTLAENRNDFFTGGIMIAERHAKKGNEHE
RLIEKYKQGCNFFISQAIYDTQATIDILTRYAIECKEQGLKPQRIILTFSPCGSAKTLEF
IEWLGVSVPEATSLRILNAENPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRKE
EIDGSILLYKLLRSSMDSHLAKHEFRLLKRKARANKLASA
>A0A7X5BK78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. V26_P1S5P106|TrEMBL
MGYTHASHIDALNQSISEVSDINVSFEFFPPSTPKMEETLWNSVHRLKNLNPKFVSVTYG
ANSGERDRTHSIIKAIKEQTGLIAAPHLTCIDASRDELITIADDYWHNGIQSIVALRGDI
PLGGGKPEMYAADLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPQWMAKQFDG
LDDDPVTRQLVGASQAIDMIRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPR
>H2JCA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. BNL1100|TrEMBL
MNIFINRDYFLFDGAMGTYYSSKNKNNTPCEFANISERENILNIHLEYIQAGVNAIKTNT
FGANRFSLGCQQSEVDRIIKSGYDIAVQACSGQEVAVFADIGPIPDGKGANPEEEYKKIV
DIFMECGAKNFLFETFSSTDILTGVAAYIRLRLPDAVIITSFAVYPDGYSKEGLFYIDIM
EKMYASGLVDAVGLNCISGPAHMYRLIKKADIRGKNIIIMPNSGYPGTERGRTVYYDNSE
YYAEKLLDIMKLGVKILGGCCGTTPRHIAAAAKLLTSPQPVESNTDISTHMEICDLEYEN
ILDRLVKNKKPILVEVDPPFDTNWEYMLRDTLILKQAGADIITIADSPLAKARAESTIMA
AKIQREVAIPVMPHITCRDKNLLGIKASLLGVHIEGIRNVLVITGDPIANIESSRIKGVF
SFNSSNLANYIKSLNSNVFCGQDIKIAGALNVNAVNFSAELKKAFTKIENGISCFLTQAI
YTKGAVENLQKAVEALNVPIFAGFMPIVSYKNAQFINNEVPGIDIDIETIEKFRDRSREE
SEKLGMEITMDIVEEIYPHVSGFYLMTPLKRTGVICELIKKIKEI
>A0A519VZC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKITDHINNSKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADHSFVPTKGGHCYATDLIQHIKNHNDGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNADFKYLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPDELTDALSYAKSNAEAKEIGTDAMIKQCKELIDFGVPVLHF
YTMGKPQQTKAIAKAIF
>A0A561SPA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia hierapolitana|TrEMBL
MAHGLCRTAVGAGSRRKLPDVADLAGALRRVSYEVLPLKGTEETVVDHVPRDVPLTVSTS
HAKGPEPTIDLAVRLTGHGYSVAPHLAARQIRDTAHLSDLVARLRDAGIDSAFIIGGDAP
EPAGPFDDAFALLVALDDLGHPFQRIGVAGYPEGHARIETDLLDEALEKKAPYATHVITQ
ICFDAAATVGWARQVKERGVVLPVRVGLPGVVSRQKLVRISAGLGLGQSARFLLKQQSLF
WRFFLPGGYHPGRLANRLAPHLHRPATELDGFHFFTFNEVASTEAWRRSMLDRVS
>A0A519YST4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKITDHIKNAAGKTLFSFELLPPVKGKSIDSIYKAIDPLMEFEPPFIDVTYHREDFIYKQ
HDNGLLEKVSYRKRPGTVAICAAIMNRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADASFIPTPGGHAFATDLLAQVQDMNHGKYLHEDHAAFKTDFCIGVAGYP
EKHFESP
>A0A1S9P1H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces antibioticus|TrEMBL
MNPLNTALSAVSTSLLEDFSLEMTGKDVPKLQEASGCIPRGTRINVTFLGNENLRMRVDA
ARAVKRLGFVPVPHISARRLGSRPEFEEFLAALRAEGACDNVFSVGGDPTRPEGPYQDSL
ALIESGLLTEYGVRHVGISGYPEGHPAISEDILWAALRSKSEALAAQGLDGSVITQFGFD
VDPVLAWIEQVRDRGIAIPIRIGVPGPAGVRRLMSYAARFGVGTSASIARKYGLSITNLM
GTAGPDRFLGALAEGYDQGRHGDIKIHFYTFGGLRATSEWIARFRKEDLA
>A0A1N7N4W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zobellia uliginosa|TrEMBL
MKITDHIKNAKGKTLFSFEIIPPVKGHQIQQLYDNIDPLMDFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYNVDTVPHVLCGGFTREETEYLLVDCHYLGIDNI
MALRGDAMKDEKYFQPTKGGHAYAVDLVKQVHELNCGNYLHDTVETDNCADFCIGVAGYP
EKHLEAPSLKSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEEAKKMGINIPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVDDCASNKEVRQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAEKIF
>B4W9S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. BAL3|TrEMBL
MMAASSTNLAEARALLLSPLGPVARAGSNHDAVRVSFEFFPPKTDEAEANLWTAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIIAETSLRPAAHLTCVEASRDEVDEVIAGYKTIG
VDHIVALRGDPPGGGGIGGVYQPRADGYANATELTAAISRVGGFDVTVGAYPEKHPESPS
IDHDIDVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLT
RMCGACGTSIPDWLKAHFDGLDDDPETRRLLAASVAAETCARLHEEGFSDFHFYTLNRAD
LVYAICRVLGVREQKAAA
>A0A095SBK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax jadensis T9|TrEMBL
MSKRISFEFFPPKTDAGKEKLLATQQKLLAKNPEFFSCTFGAGGSTRDNTRDMVNQLRNQ
HGDTAPHLSCIGQSREEILELVNGYKAAGVTRIVALRGDLPSGMGYAQSEIKYADELVQL
IREETGDHFTLEVAGYPEMHPQARSFEDDIAHFKRKIDAGANSGLTQYFYNADAYGYYLD
ALQKIGCDAPVYPGIMPILNVANLVRFSSTCGADIPRWLHSKLNDIKDDDAAVKAFGEEV
VTRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGL
>A0A1V2ZF56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. VKM Ac-2630|TrEMBL
MTRARFEIIPTADIAERARRAFPDPSAVVLTVTSLPKHGLERTLDAAVELAALGFGVVPH
LAARTVEGRPALERALGRLGDSGIVEAFVVSGDAKKASGTYSTSLELLRDAVEIMPDLAV
GIAGYPEGHPHLSDESILKHLRERAPYIRSIVTQMCFDVDAVARYADSLRTEGIDAELWA
GIPGPVERAKLLSLGAKIGVGSSLGFLTRSSSVAGGLLRGRRFDPTAFVGRLEAAAGDRL
HGLHVYTFNELDGLAAFGS
>A0A317K6S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora globispora|TrEMBL
MALGLPSVLPNPQPAIGALIRDGQPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVELTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVPHPEGVRYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCQAGAEFAITQMFFDADDYLRLRDRVASAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFERVADDPEAVRRLGIEQASEMCARLLDEGVPGMHFITLNRSTATREVWQHLR
ADARV
>A0A1F9X4M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFOXYB2_FULL_50_12|TrEMBL
MNTFKRKLDDNKFVITVELLPPKGTDVSALMEKARMLQGAVDAINVTDNQRASMRLGSLA
VCRLLKERGHETVLQMTCRDRNRIALQSDLLSASALGIENILILSGDHPRNSENRGAKPV
YDLDTVQLISAARLLEQGVDMAGKKLEGKPCFNIGAVVNPASDNADLQIMMMEKKASAGA
VFFQTQPVFDIDQYSIFAGRIKHIPAKIIPGVALLKSASFVNFLRSIPGITIPDEVARRV
EAAPDQLKEGIAICAETIRELKKISHGVHIMAIGMEAHIPEILSRID
>A0A182PQF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles epiroticus|TrEMBL
MADRPLPASNSLAEEEALHTKLNGIFTSTTHPSPVCYSIEIAAKDDFDLRQLERLTPQPV
FISLPWILDENLRYADDFIRSPMLQLSSQLRKSHYTVVNHVSCYNITEQQVDALLSTGIR
NLFVIRGDTVSPEQKFQNASGLVQYLRKQEQQQTDNHHRQLTIGVGGYPYGHHQSHSETD
ELRYLREKIGNGADFLLTQTLYDAQSFLRYRDRCREAGISIPIIPGIYIPHSYRHLQVML
KLTRIELAPMVQTAFEAHADDAPEQFEAFMVQYFVKVVRELLESNVTSSSSDPIKLVHFF
TFNKFGLLQQVLQKLEHFFK
>A0A7C5DYF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
KNPTGFFIGVGVNPSAVDLDYEISRFEWKVKAGAQFAITQPVFDAGQFTEFLKRIEHVRI
PIIAGVWPLVSVQNAEFLNNEMPGAFVPDEIIKRMKAAKNKEGAQKTGIQIARELLKELK
VHLAGAQVSMPFGKVDAPLEVLKDVL
>A0A837DX51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ligilactobacillus ruminis DPC 6832|TrEMBL
MSQTTFSFEIFPPNKESAAEKLTETLDELVGLSPDFISVTCTNKNDDLARLTVKLAGYVK
NRLNVPSIAHLPAAYLDKQQVSEILNELETLGVTNLLALRGDRIEGRKPRDDFRHVSDLI
AYVHENFPDFHISAACYPEIHPESNSRVDDIKHLKYKTDQGVDSLITQMFFDNESFYRFR
ECCELADINTPIVAGIMPIVKRKQALRILNTSSATLPKKFTAILNKYHDDPESLKAAGLA
YAIDQIVDLVTQGVAGIHLYTMNDAETAKYIWQATRSLFENGRKVHQA
>A0A7Y4S5Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuriferula sp|TrEMBL
MSTRTFSFEFFPPKTPEGMDKLRDVRGQLATLQPKFFSVTFGAGGSTRDHSLATVLDIQN
AGLEAAPHLSCIGSTHDNIRAILNEYQSNNIRHIVALRGDLPSGMASTGEFRYANELVEF
IRNETGDWFNIEVAAYPEVHPQAKNAHDDLINFKRKMDAGANAAITQYFFNADAYFAFVD
DCAKLGITAPIVPGIMPIGNFSQLARFSDACGAEIPRWMRKKLEGYHDDIDSIRAYGLDV
VTDMCQHLLDNDAPGLHFYTMNQATATMEMWRRLGL
>A0A6F8XS17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytohabitans flavus|TrEMBL
MSESGLKARTAASGLRGALADGRFVVTAEVAPPRDADTEAIARKVGALRGWVDAANVTDN
QGGNVRMSSLAGSILVQRAGLDPVMQLTCRDRNRLALQSDLIGAAALGIRNVLLLTGDHP
TLGDHPDAKPVFDLDGVQLVWTARTLRDEGTLLSGKRLGVRPSWLIGTVENPFAPPAELR
ARRLAKKVAAGAEFVQTQYVFDVDAFARWLRPLRDEGVTERCAVIAGVGPIRSRRMLSFL
TGTVPGIHVPESVRRRLAGVPEQRVEEEGRRVCVETIEALAALDGVRGVHLMVFGHEDEV
PDIVRQAGIRQATKGGDDAD
>A0A831PCC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MTRVTERLQNGDRPLLSLEITPPDRGQSIDELFHNIDSLMPMSPEFINVTYHQAYEDYEE
KNGSIVRRPRRKKPGTVGICAAIKNRFAVEPVAHLICGGFDRWETEDALIDLHYLGIRNI
LALRGDPPPGQSLFRPKKDGYAFAADLVAQIRDMNQGVYVDALDDPVPTSFSIGVAGYPE
KHVEAANRETDIRHLKEKVDQGADYVVTQMFFSARLYKDYVARAREAGITVPIIPGIKPI
TTPRQLERIPRTFFVSLPDALVQSICEARTAKEAFKRGTDSVAELAGELLEAGAPGLHLF
TMGKGRGARAVLTRLFGSHR
>A0A6S5XVS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKGVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A6N2KDQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salix viminalis|TrEMBL
MASRMFLLFVAILLMVRINSSRSKAASLALSTWSNISDPNMVITSALLLLAIQDYHKDLA
YLKQKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFC
KTKVPAEVTAALELKRPSEPMGFTLELKCARRF
>A0A833NWU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Saganbacteria bacterium|TrEMBL
MNFSEALKSGKFLITAELSPPKGVEVEPIIQAASVFKSKVDAVNVTDNQRARLHLSSLAF
CRLLHEQGFEPILQMTCRDRNALALQSDILGAYALGLRNILALSGDYPKGGSVRPVYDLD
SVQLISTIKKMENEGIDLFGEKLAGKMNFFVGGAINPGAEPVEQQILKTEKKIEAGVDFF
QTQVIYGIELFKRFFTKLNNRKAKVIAGIFPLKSYNMAVFLNEKVPGVFVPEEILKRMKE
SRTPETEGIKISIEIINELKPVCSGIHIMTLNNDVDIIAEILNKI
>A0A6N7IH42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangiales bacterium|TrEMBL
MRDLLAEGGQSFSFEFFPPKTDEGERNLWQAIRELEPLSPTFVSVTYGAGGHSRDRTVRV
TEGIAANTTLTPMGHLTLVNHSVAELRHVIGQYADAGIRNILALRGDPPGDPQGEWVPHP
EGFSYAEELARLVKSCGDFSVGVAAFPEKHPRARDHDTDVRFLIQKARAGADFAITQFFF
HAEDYLRLRDRVAARGCHIPIVAGIMPVTNVRQIQKFAQLSGAQFPVDLAERLYAVEDDP
AAVRAIGVDYASRLCELLLAEGVPGLHFYTLNRSTATREIYQQLGLGQRGFSGSREPMTA
>R6V7P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:380|TrEMBL
MKITEVLKSDKVTLSMEVFPPKTTTAAEKVNEAVRDIAALKPHFMSVTYGAAGGGTSKYT
IQIAKDIKDAYGVNSLAHLTCLSSTKETVEKQITLMKEAGIENILALRGDIPKETEFPLP
GQFHYAAELVREIKCIAPEMCIGGACYPEGHPEANSKAMDILHIKEKVDAGCEFLTTQMF
FDNSIFYNYLYRLREAGVMVPIIAGIMPITKKNQVARSIQLSGSCVPARFKSIVDWFGDE
PAKMKQAGIAYATDQIIDLIANGVKHIHVYTMNDPEVAAGIQRNLSEIIG
>A0A2A2A2P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. NML 120412|TrEMBL
MRGTFAPTRLSASAPIDRVGEDTTQQRRRTRTALSFELIPPRHGADEGKLDELIAGLAAY
RPDYVSVTSSRRSDWLTGTAALIARVAETTNLRPIAHLACTAGTREELVTWIRTLIDAGV
RGFLALRGDLPETGMPADHLQHATDLLNLIQDVEDEEAFRLAAGKLALSVACYPSGHAES
KNFDEDLDVLLSKQRLGADFAITQLFFNAQDYLDFVEVARLAGVRIPLIPGIMPMTSLKR
VQRMGELSGIEVPECVARTLAQATTPEEEYELGMQMSARLANTILDAGTGGLHVYTHNNL
AVTQDLLSRIGIPQRADHSPQ
>A0A258M530|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriia bacterium 35-40-8|TrEMBL
RIFHVDIPTDLSNAISKCKTDADCEQVGTEWLIQQSKELKAFGVPVLHYYTLGKPKVIWN
VVKEIV
>A0A1U7MK24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa sphaeroides DSM 2875|TrEMBL
MSEAVAIDKQAVLKTESKLEKLYSLGHFVVTGELGPPQHSNGHELEHHAHELKDIVDGFN
LTDNQTAIVRLSSIAAGVHVLKGGGVPIIQMTCRDRNRIAMQSDLLGAYSIGIRDVLCLS
GDHQSFGNHPTSKNVYDVDSVQLISMVKKMRDDKKFLSDAVIKTDEPRFFIGAVENPFGD
PFEFRAIRLEKKVNAGADFIQTQAIFDIEKFARFMEMVVARGIHERTKITAGILPVRSVK
ALQYMKKDVAGMEIPDSLIERMKKTEDPKKEGIQVAIEMCNELKKIPGVAGIHIMPVGWE
AALPEIVKGAGFLPRPKV
>A0A6B2YLU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID14446|TrEMBL
MALGSASTRTDRARTVRDMLATGKQTCSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVLDTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSTEWDLDVSHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAEAGCDTPVIPEIMPVTSVRMLERLPQLSNASL
PDALKERILTVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A1G5TRX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. NFR15|TrEMBL
MTISVSQLEEARRALEAPLFADVAGDTAVSFEFFPPKTPKMEEALWETVKTLEPFGPRFV
SVTYGAGGSTRERTHATVARIQSETGTPAAAHLTCVEASKDEIDAIADAYWQAGVRHIVA
LRGDAPGADGFVPHPQGYTNAADLVAGLKRLHPFEISVAAYPECHPDSRGVSDDLDNLKR
KIDAGATRGITQFFFEPETFFRFRDRAVAAGITAEMVPGIMPVTNFASIVKMSAMCGTEV
PAWLGRLFEGLEDHATARQLIAATLAAELCRKLYAGDVRALHFYTLNRAELSFAICHMLG
LRAKVPAKVAEAA
>K6ZHZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciecola pallidula DSM 14239 = ACAM 615|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPNSEAMENTLWKSVERLAPLKPKYMSVTYGA
NSGERDRTHAVVKRIYKETGVSTAPHLTCVDATPDELKLIAKDYWDSGIRRIVALRGDLP
KGVDKTDMHASDLVTLLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAQAGANEAIT
QFFFDTSVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLQRFAGFTNVHVPNWLHKMYEGL
DADDQATRNLMGANIAMDMVKVLAKEGVKHFHFYTLNRCELSYAICHMLGLRSQK
>A0A427KKN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A157BVN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A0A8WRG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp. OR-1|TrEMBL
MNSIDRLKNEILVGDGAIGTMLYAKGVGLEVNFEHLNLVRPELVLELHREYLAAGAQVIE
TNTFGANRSRLQTIGLEAKVAEINRRGAAIARQAAGETRLVAGSIGPLARLKGEEKLLPA
KEQQGIFLEQAEALAAGGVDLLLLETFSDLDQAINAVVAAKSTGLPVIASMAFVEGGRTA
SGFTVEEVAQGLTAAGADILGTNCGAGPLELLRIVRRLASATRLPLAAYANSGFPEFVDG
RRIYRCTPEYFAGMAAEMAAAGATLIGGCCGTTPDHIRAVALRLAGMKAAPRAMILPGST
DGLSAVETVLRPGFLSDWGKRPIITVELDPPAGMDTARVLAGSRELKRAGADAINLAENP
LARVRVGNIALGSIIQNEIGIEVIPHITCRDRNLLGLQSDLMGAGLLGIRNILAVTGDPA
RLGDQSGASSVYDLNSFQLIKLIADLNRGFNAVGNRIGAGTGFTIGCAFNPNSPKMQVQV
GRLEKKIASGAQFVQTQPIYEPEVLDAMLRDTAHLGIPILPGILPLVSERNCEYLHNEVP
GIIIPENIRRRMKGKDKEEGVREGLAIAREFIASARDRVGGFYLIPPFGRCAIAVELIRF
IREGE
>A0A7Y7C4F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcus sp. AM010|TrEMBL
MKIRNRLNPSDPCFSFEFFPPRTDEGEKNLLKALEDLATLQPGFVSVTEGAGGSTRTKTV
DLVLRIKQETGIEAMAHLTCGGHSPAELRTVLERLSAAKVDNVLVLRGDPPKGQTRFEPV
SGGFRYASEMVRFIREEDFNFCLGGACYPEGHVETPSRDDDLRHLKAKVDAGLDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQIQRFTRLCGATVPMRLALQLERVKD
NPEAMAQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRARS
>A0A0U5B6U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aneurinibacillus soli|TrEMBL
MAKENLKQYLQDHLLIGDGAMATWLYRLGVPIGVCYEELTLSNPELIGSVHRSYYDAGAR
FIQTNTYGAHRDSLARHGLGHKVTRINRKAAQLARESVGEDAYIAGGIGSINGGRVRDTN
IQPYAEQFEEQTEALLLGGVDAILLETFLDLDELLLALNVIRPMTDLPIIAQLATIEVGR
TRDGFTLSQAFAEMKKAGADIVGLNCRLGPAEALRSIEQTIIPDDTPFSVFPNAGRLAIS
DGEYSYASVPQYFGDSALRFRTQGARLIGGCCGTTPEHIRMMAQVLAEREPLPRVNPVRE
AEEAFVPIEIGSPSVRPPSIVDTVKERHTIIVELDPPRDLDTERFLAGTAALQDAGADAV
TLADNSLATTRMSNLALGAMMKSKLGAEPLLHIACRDRNLIGQQSHLMGMHALGIHQALV
ITGDPARFGDLPGASSVFDVSSFDLIRMIKQLNEGFTFSGKPLKQRANFVVGAAFNPHVR
QFDAALRRLEKKIEAGADYIMTQPVYDVEMIERIHEGAKHLDVPIFIGIMPLTGSRNAEF
LHNEVPGIRLSDEARERMRKFESGPEARAEGVAIARELTDAAMAYFNGIYLITPFFYYEM
TAELTRYIRQKSSVVL
>A0A7S3BL71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prasinoderma singulare|TrEMBL
MHVIDKIAEKKARGERWFSFEYFPPRTPEGVENVFERMDRMARVGPLFCDITWGAGGTTA
ELTLDMAARMQNEVCVETMMHLTCTNMKVEMIAHALKTAKEAGLTNILALRGDPPKGEDN
WTAAVGGFSCGLDLIKYIKQEHGDYFGLACAGYPEAHPDAIGEGGVATAEAYSKDLAYLK
QKCDAGAQVIVTQLFYDADVFLKFVDDCRAIGITAEILPGIMPIQTYGGFKRMTGFCKTR
VPQSVLDTVEPIKDNDEAIKAYGIHLGYEMCKKILDAGKTQGLHMYSLNLERTAMGILQR
LGLVDDRAPPRELPFRPPTNPKRSDESVRPLYWGNRPKSYLDRTKDWKAFPSAHWQHAGS
FGEFKAGARRYKVDRKVAWGTPECEEDVAAVFAGFVRGDISALPWSESEGLAVESSAITA
RLVELNSKGFLTINSQPRVNGVDSATPGVGWGPSGGMVYQRAYLEFFCSKAKFETLKEHL
VRHPSMSYMASDRSGELWETNCSGTNAVTWGIFPNCEVAQPTIADPDAFKVWKDEAFALW
ESDWAAIYGGSTCSREVITNIASSYVLVNIVDNNFVDGDIFSVFASLFYLP
>A0A832E3P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nannocystis exedens|TrEMBL
MLIRERLLHKQPIFSFELFPPKTRKGEATLWRSLESLANLEPDFVSVTYGAGGSTRARTL
EIVTRIKRELGIEAVAHLTCVGSTREELRRTVGELGDRGVHNILALRGDPPKGETAFVPT
EGGLRYASELVALVRDEGDFCVGAACYPEVHPEAKNAAADLQHLKTKVDAGADYLITQLF
FDNGLYHRFVADAAAAGIDVPILAGIMPVTNYRQIERFSRMCGASLPRLLQERLHRVEDD
PQEVFWTGVIYAAHQCRALLEPGQPEAFKKRPKGVPGVHFYTLNRSPATRAIFEILRLAR
SAVF
>A0A1B1I8X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella scopos JCM 17725|TrEMBL
MDNNIANIKHLLNDETGEKHFSFEVLPPLKGNGAASLFRNIDKLKEFNPSFINITTHHSE
FVYHEREDGLIERKRIRRRPGTVAIAAAIQQTYGIPVIPHVICSGATKEDIEYELLDLQF
LGIENLMLLRGDKAQEDKIFKPSKGGHRHTTGLIKQVNLFNEGVFIDGSTMKHPGKPFVY
GVACYPEKHEEAPNLEQDLRHLKKKQDLGATFAVTQLFYDNEKFYNFVDLARKKGITIPI
IPGIKPFAKLSQLTVVPKTFHCDIPEELAELALMCKSDEEACLLGIDWAVKQVKDLYAHG
FNNVHFYTVSAVNSVHEVMKRLVETGLLQKNNK
>A0A4U5X328|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces galbus|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTFSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPQGLTYAAELVELIKASGDFCVGVAAFPAMHPRSADRDADVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVAAAGCDTPIIPEVMPIASVRTLERIASLTNAAF
PTALKERILTAKDDPSAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHPPQA
>A0A413FG33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster asparagiformis|TrEMBL
MKIRDILAAGKPTLSFEVFPPKTVDAYEPVERAACEIAKLKPAFMSVTYGAGGGTSRYTV
DIADTIKGYGVTPLAHLTCVSSTREKVHQVLDELKSRGIENVLALRGDLPADGETPREYR
YASQLIREIKESGDFCIGAACYPEGHVESANKSVDMDYLKEKVEAGCDFVTTQMFFDNSI
LYSYLYRIREKGITVPVIAGIMPVTNAKQISRITGMSGTYLPARFKAIVDRFGDNPAAMK
QAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAARIRENLSEIL
>A0A654DTL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinoscillum sp. 108|TrEMBL
MKVTEHIKASTESTLFSLEIIPPKKGDSIDSLFAHIDPLMEFKPPFIDVTYHREEFVYKN
RENGLLEKKTIRKRPGTVGICAAIKNRYNVDPVPHIICGGFTKEETENALIDLNFLGIDN
VLVLRGDSIAEEKTFRPEPDGNAYAIDLVDQVMGMNEARYLDEELQNAVPTSFCIGVAGY
PEKHFEAPNLRSDLKYLKQKVDRGAEYIVTQMFFENSKYFEFVDKCRAAGINVPIIPGLK
PITTKSHMTALPSIFHIDIPDDLYNEIEKCKDNKAVKEVGIEWGIQQSKELMEKGVPVLH
YYSMGKSDSVYRIAKALF
>A0A1H3XAS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalimonas amylolytica|TrEMBL
MSFAHAQFLEAINRNLHDVQGKTKVSFEFFPPKTEQMEQTLWQSIERLAPLTPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASVEELKQIARDYWDNGIRHIVALRGD
LPAGTTEKPALYAADLVEILRSVADFDISVAAYPEVHPEAPNAQFDLLNLKRKVDAGASR
AITQFFFDVEKFLRYRDRCAAVGIDVDIIPGILPVTNFKQLLKFAALTNVAVPGWMHNAY
EGLEQDATTRNLVAANIAMEMVKVLSREGVEHFHFYTLNRSELSYAICHLLGVRPIAQPQ
V
>A0A1I0WB86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poseidonocella pacifica|TrEMBL
MPTPTVSFEFFPPKDLQGSFRLWDTVQVLAPLGPRFVSVTYGAGGTTRDLTRDAVSTLHH
HSGLNVAAHLTCVNASREETLEIARTYAAAGVTEIVALRGDPPKGSGGFKPHPDGFADSC
ELITALKNTGDFTIRVGAYPEKHPEALDEAADLDWLKRKIDAGADEAITQFFFSADTFLR
FRDRAVAAGITAPIVPGILPIENWKGVKRFAESCGTSVPTWLSNAFETAIRDGREDLLAT
SLCTELCSKLVDHGVESLHFYTLNRPELTRDVCHALGIVPSMQLENVA
>A0A1E9JDL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium sp. HMSC073F01|TrEMBL
MKISELFKRKKTIVSFEVFPPNSIYSLEDVYSSIDELAKLQPDFISVTYGAGGATRGNTV
EIASKIKNNNKIEALAHLTCLGAKKNEIDDILKQLRANNIENILALRGDKPKDCTPIGEG
DFKYAQDLISYVKEKREFSIGGAYYPEGHLETNDLLDLFNLKRKVDSGTDFLISQIFFDN
ESFYRFRDKLNKLQINIPLVAGIMPVTNAKQIRKITSMCGCSIPEKFQKILNKYENNTQA
LKEAGTAYATEQIIDLITSDIDGIHLYTMNKVDTAKKIMANIAHIREISGGNR
>A0A2B8AZN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ru87|TrEMBL
MALGTPSTRTDHAHTVRDLLASGKQSYSFEFAAPKTEKGERTLWKAIRRIEAVAPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSVAELRNVIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPQGVGYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWESDVRHFVD
KCRAGADFAITQMFFYADDYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFAQLSNATF
PPELADRILAVKDDAAAVRSIGIEYATELCARLMAEGIPGLHFITLNHSTATLEIYENLG
LHQRP
>A0A6I5HZN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4913|TrEMBL
MRPLRELLARGERSFSFEFFPPKSEAGTRVLWDAIRRIEPLAPSFVSVTYGAGGSSRDRT
MEVTERIVSETTLRPVAHLTAIGQSTAELRRVIGQYAQAGVRDVLALRGDPPGDPNAPWS
PHPQGLRYARELVSLVRESGDFSIGVAAFPERHPRSPDWESDIRHFVAKCRAGADYAITQ
MFFHVEDYLRLRDRVAAAGCDTPIIPEIMPATDFRQIARFAELSHATFPDDLARRLEAAR
ENSAEGRRIGVEYATAMVDRLLDEGAPGLHYITLNRSTATLEIHRGILGSRSTHALALS
>A0A2Y9QA76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delphinapterus leucas|TrEMBL
MDRPKPKVLPAGHCCPSLGMRAWEAGSARFSVPPSISRSSAMVNEPRGHGGPSPRWEGSS
SGSESSKDSSRCPTPVLDPERHERLREKMRRRVESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKRLGLKNILALRGDPIGDQWEEEDGGFNYAVDLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEAGLKHLKEKVAAGADFVITQLFFEADTFFRFVRACSEIGITCPILPGIFPIQ
GYRSLRQLVKLSKLEVPQQVKDVIEPIKDNDAAIRNYGIEQALSLCRELLASGSVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGW
GPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGDNITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQHIHDNYFLVN
LVDNEFPLDSCLWQVVEDTFELLSGPHQSKRETEAP
>A0A843IC31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon|TrEMBL
PLKIRDKALLLEGCADAFNVTDNQTAVVRMSSLAGSVLLLQMEFEPIMQMTCRDRNRIGL
QSDVLGATALGIRNILCLTGDHQSFGNHPEAKGVFDIDSLQLLQILKKMQDEGVFQSGDP
LRGTRPIVFLGAAANPYADPYEIQVDRLRKKIDAGAQFIQTQSVYNLEKFTTWMDEVRTQ
GLDKKVHILAGVTPLKSVKMAERMKFHVPGTDVPDTVFEQIRNAADPAKEGYAIALNTIR
ELRHLKGIHGIHITALFWEEIIPALVRESGLLSR
>A0A737IVZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 42:b:1,5|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7J3TEM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon|TrEMBL
MLADLSDMFTAPENPRGLPGIDPVIALYEATRNNDIIPMPHITPRDKNALFIRSQAITAM
KFGINHFFVIGGDPISPDANSKEVREIDVMETISEISRSEKLFKPREGDQREIVVGSAIN
PYRSNEEEIASKKIENGSSLFISQIIFDPQLLEKDWIKKRNFKIMAGFMAIRKKSQVDFA
EKLHINMPAEIREKFQNSDDIASTSRKVILEAFDSLKGYVDGIHLMPLGHNNLAKDILEC
I
>A0A6P0YZP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Merismopedia sp. SIO2A8|TrEMBL
MSNAIQNSKSQIATETVSLSNYLQDTTPTKNSFRHAAESGKFLITAEVTPPKGGNPAQMV
KMAKTLKGRVHAVNITDGSRAVLRMSSLAASVILLQQGLEPICQLACRDRNRIALQADLM
GANALGICNILALTGDPVKAGDHPEAKSVFDLESVRLLQLISKLNQGVDAHDKPLTDDVT
DLFAGAAVDPQLKSWSGLQRRFERKIEAGAQFFQSQLITDFERLEKFMDEIAAGSNKPIL
AGIFLLKSAKNARFINKYVPGVNIPEAIIERLAAAKEPLLEGMNIAAEQVQIAQQICQGV
HMMAVKREDLIPQILDLAGTSVIVNSS
>A0A5K7X212|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporolactobacillus terrae|TrEMBL
MGHSILDVLKERILIGDGAMGTLLYSYGIDRCFEELNVSQSEAVRHVHEAYINAGADVIQ
TNSYGANRIKLARYGLEHEVARFNRASVQLAKQAAKPETFVLGTIGGIRGFQKQSVELDT
IRASFREQADALLSEGIDALLLETYYDFDELRDVLQIARTMTDLPIITHVSMQEPGVLQN
GMPVAKALEGLEAQGADVVGTNCRLGPFHMIEALRGIPLPKKAFLSAYPNSSLPDYRDGK
LHYENEPEYFKKYAVDFRNEGVRLLGGCCGTTPVQIKAFKAGISALEPLKTKVVTVHPEV
VHVSEAAEPPESALYQKSVHGRSVFVEFDTPRHLNTDHFFRGVQALEAAGADAITMADNS
LASPRISNAAIGKLVKDRFHMPPLVHLTCRDRNLIGLQSHLLGLDVLGLHDLLVITGDPT
KIGDFPGATSVYDVSSMELIKLIKQFNRGISYSGKSLKKPTHFRVAAAFNPNVRNLDRAV
QRLKRKIECGADYFISQPVFDKERIIAISEATRDISAPIYIGIMPLTSARNAEFLHNEVP
GIRLPDDVRAKMAATSGKEEARQVSLDICRELIDTAMAHFRGIYLITPMSHYSMSVDLVK
YIKKKEREYTALENSENMLL
>A0A7C7N7A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospina sp|TrEMBL
MKIIDVLKQDKPAFSFEFFPPKDNDGFDKLFETIDNLKALNPAFVSVTYGAGGSTRSKTI
DLVGRIKKEIRLESMAHLTCVGHNSDEILNVLESIKKQNVENVLALRGDPPAGEINFTKP
NNGFGYAVELVQFICERFSFCIGVAGYPEGHPESSNREEDLFHLKKKVLAGASFIVTQLF
FDNKYYFDFVASLRKIGVDVPVIPGIMPIVNLKQIKRFTKMCGATIPHDLMVRLEEAQDD
PESVCQIGIDHAANQCRKLLMHGAPGIHFYTLNRSRATLSVLERLV
>A0A844CGF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fundicoccus ignavus|TrEMBL
MTDSQRGNGTSLSFEVFPANTQVGTKKLIQTLNELQDLQPNFISVTCSNNKANIEETTVK
IADYVTNTLRIPTIAHLPAAYLSKQQVSTILGQLEKLGIRHVLALRGDIVEGIPPKRDFS
YASDLVTFIQEQAPYFDISGACYPEIHPDSDNRISDIKHLRKKVEAGCSQLITQLFFDNE
QFYQFKEGCSLAEIDAPILAGIMPIVNRKQALRLIKVSSSQLPKKFLAILEKYEHDPVAL
RDAGLAYAIDQIVDLVTQGVAGIHLYTMNQSDTARQIHQATKSLFQTTELLGV
>A0A4R7P467|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panacagrimonas perspica|TrEMBL
MSAAGPSYSFELFPPRTPEGAAKLPAVVAKLASVKPSFFSVTYGAGGSDQDGTYETVCRV
VTDTGIEAAPHLTCVGSTRAKVAELLGRYKAAGVKRIVALRGDLPATSHGTEAPGEFGYA
NELVEFIRVTHGRDFQIEVAAYPEMHPQAASPEADFAAFKRKAEAGADTAITQYFFNADA
YFDFQNRCARANLKIPIVAGIMPITNHAQLTRFSAACGAEIPRWIRLRLELLKDDKAAIL
DFGTEVVTRLCETLIKGGAPGIHFYTLNQSEPTLRLWRNLGLS
>A0A1V5EAX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium PtaU1.Bin231|TrEMBL
MKIRDAFTRKTPTLSFEVFPPAREGNVESLYETIRELGDWKPDFISVTYGAGGSTRDKTI
EIAAKVKKDFHHEVLAHLTCVQSTRDDIAGILDALKNETIENILALRGDPPDGTGVFRRI
EGGFGYANELVEFIRSRSDFCVGVAGYPEGHCEAPSLDEDIRNLKRKIDAGADFIITQLF
FDNDDFYRFRERVMKCGVRVPIVPGIFPILNYKQSQRIGSLCAPKLPPALREKIEKYRDK
PEEIEKYGIEHAARQSEHLLRNEAAGIHIYSMNRSGPVRRILAELPLDPARRASKKG
>A0A2N1S9V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetae bacterium HGW-Spirochaetae-3|TrEMBL
MNNVLEALARKPRRVSIEIVPPSRGGDPDGAIACVEAVAPFEPAFVSVTDHPAGRAWLDR
DGKPIEVPLRGKPGTLGLCVAIRERTGAVVVPHVVCLGSDRFKAEDQLIDLRYAGFKDVF
IVRGDERFAPFAEKPGRAVDGLLPRAVDLVRIVAAMNAGDYLSDGSTGSPAGLSVGVAAY
PEKHPSSPNPDADLAALAEKVNAGAAWIATQMVFYASRYAEFAARAKAAGITAPIIPGVK
PLVRAKSLAGVPGTFFVDVPPELAAALSEARSPAEERLAGIKHAAALVEALYDAGAPCVH
FFTMGKARDAVETMEAVFGKASGGSR
>A0A1N6JK97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga niabensis|TrEMBL
MKVTEHISQAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPSFINVTYHRSEHMFKKR
ADGSFDKVEIRKRPGTVGICAAIMNHYQVDAVPHLICGGFSKEETENALIDLNFLGIDNV
LVLRGDAPKNETFFEAHPNGHRYAIDLLQQVAQMNNGIYLEEDLMGGLKTKFCIGIAAYP
EKHFEAPNMQTDMMYLQRKVEAGADYIVTQMFFDNKKYFDFVAKCRDMGITIPIIPGLKP
LSTKKQMTILPRTFHVDMPEDLYTEVNKCKTDKEVELVGTEWLIQQSKELKAAGVPVLHY
YTLGKPHVVRKVVETVM
>A0A5K7YBE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia sp. AM6|TrEMBL
MTSRLTIPDNTQLSSAEGIGNVGRLEQVLRSGQFAVTAELAPPDSADPQEVHARAQLFAG
HVDAMNATDGSGANCHMSSVAMCALLAREGHETVMQISCRDRNRIAIQGDVLGAAALGIR
NLLCLTGDGVQVGDHPEAKPVFDLDSLSLLEIVAGLRDKHTFASGRALTSAPQVFLGAAA
NPFAPPFAFRPHRLAKKIAAGAQFIQTQYCFDLSRFQDFMHRARDLGLLEKCFILPGVGP
LASARTAEWMRRHVPGVHIPDDVLKRLKGARDQKAEGRDICIEMIQQLREIEGVSGVHIM
AHRQEAFVPEIIQRAGILGARMLWTPEPRPTPSP
>A0A4R5VBL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Antarcticimicrobium luteum|TrEMBL
MKAPEVSFEFFPPQNLQASFRLWDTVQVLAPLDPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLKVAAHLTCVNATKEETLEIADGFAKSGVTEIVALRGDPPKGEGRFTQYPGGFANSI
ELIEALAATGRFKIRVGAYPDVHPEAASAQADIDWLKRKLDAGADEALTQFFFESETFFR
FRDACEKAGIDGSRITPGILPIENWKGARNFARGCGTTIPQWVEDAFEKATRDGREDLLA
TAICTELSSELIEGGVERLHFYTMNRPELTRDVCHALGVTPKVSLENVA
>A0A836P350|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas vasicola pv. vasculorum NCPPB 890|TrEMBL
VSCTFGAGGSTLSYTSETVRHLKQKHGFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIV
ALRGDLPSGMGHPGDLRYASDLIAFIRAEHGDAFRIEVGAYPETHPQATDALSDLRYFKA
KVDAGADAAITQYFYNADAYFHFRDAVQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEI
PRWIGKKMQSYGDDADAVRAFGAEVVSALCERLIAGGAPALHFYTLNLAKPTTQVLQLLG
R
>A0A5Q6RPV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mumia zhuanghuii|TrEMBL
MRNQAVRRTLVRLLEHARYEVLPTPSAEAKVIEHVPLDIAVTVTASPSKGLPATLELAER
LATRGYVTVPHLAARMVSGRSELVEISERLKAAGITRVFVPGGDADPVGDYADALALLED
LAVMGHPFEQVGVTGYPESHPTIHDDLTVQAMWDKRRYATHVVSNLSFDPAVIRVWIQRM
RSRGVTMPLLLGMPGPVDRTKLLSMATKIGVGESTRFLAKNKGTFARLAAPGGFTGERFL
LKCAPTLSEPTSLVEGLHVFTFNQIEETEAWRQGLLSRLRS
>A0A7Z0B6A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia bryophila|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVVDIAK
EGIEAAPHVSCIGSSKDSLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDMDNFVRKVKAGANSVITQYFFNADAYFRFVD
DAQKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTDLCERLLDAKVPGLHFYTLNGAAATKAICERLNT
>A0A1F2JG14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. HMSC13C05|TrEMBL
MKIIDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTDGGHAFATDLLEQVTDMNKGKYLHEDIITSEKTDFCIGVAGY
PEKHFESPNFNTDFKYLKQKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVAACKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLA
>A0A417SP95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. OM05-6|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A3P1CPB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Larkinella knui|TrEMBL
MAKVSDHIRKANGKTIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
LEPDGTIKKIITRKRPGTVGICSAIMHKFGVDPVPHVLCGGFTRDETEDFLIDLHYLGID
NVLVLRGDPAKPFDTFKPKTNGYAYASELVEQVANMNRGVYLHEGSHAMTPSDFCIGVAA
YPEKHFEAVDHETDFTYLKLKIDKGADYIVTQMFFDNQKYFDFVKRCREAGITVPIIPGL
KPLSTRKQLQVLPRLFHLEMPDDFIKAVEACENDGQARQVGIEWCVQQGRELVKAGVPGL
HFYTMGKSDNIVKVAQEIF
>A0A349LMR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp|TrEMBL
MELSVEFFPPKTPEGESNLHQVRERFAETLKPTFYSVTFGAGGSTQSGTLKVVSNIHAAG
AAVAPHLSCVGSSRESVREMLKQYQTLGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
SETGDWFHIDVAAYPETHPQATSPASDVDFFVQKMKAGANSAVTQYFYNSDAYFRFVDDV
YDQGVTQPIIAGIMPIANSSQLLRFSDACGAEIPRWIRLRLQAYGDDIISIRAFGEEVVT
DLCDQLLTAGAPGIHFYSLNQADAVLAIADNLDLTK
>A0A5C7VDU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas sp|TrEMBL
MQSQKKFPATFSFELFPPQTPEGIEKLRVARSQLAQFNPKFFSVTYGAGGSTRDRTIETV
LEIQAEGRTVAPHLSCIGSTRENIYALLKKYQENGIQHLVALRGDLPSGMAQAGEFRYAN
ELVTFIRQEFGDLFRIEVAAYPEYHPQSRSAQDDFKNFIKKIEAGADSAITQYFYNADAY
FHFIDQCEAANLRIPVVPGIMPINKFTQLVRFSDTCGAEIPRWIRKKLEGYGDDSASITA
FGLDVVTELCDHLLKAGAPGLHFYTLNSATLTTKIWQRLFSNLSS
>A0A1K2IFZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium limigenitum|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYRNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERKITRMRPGTLGICSAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTKGGHESAMDLVHQINDLGRGKYLHDEQACEENNKFCIGVAGY
PEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVTKAREMGITVPIIPGIK
PIATKRHLKLLPQVFKIDLPEDLINEVESAKNNEAVKQIGVEWAINQCKELLDFGVPVLH
FYSMGKSDNIKKVAGELF
>A0A7W1R657|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MARIGDLLRTGRTVSFEFSPPRDDSAQLSLGRTIAELEPLHPSFVSVTYGAGGSTRERTR
DVVTWVRRETGITPMAHLTCQGHTRAEVAQLLDEYQEAGIENILALGGDPPKDPADQRPS
EYTYATDLIDDLDTRNHFSIGVAAHPEVHPRSPDRETDRLRLAAKLRRADFAITQFFFEA
HHYVEMVDELADLGVDKPVLPGIMPVTNGRQVTRMAELSGADVPSFVTDRIAGLDNPADV
RSAGVEMASELCAALLAAGAPGLHFYTLNRSTATREIYANLGLTTS
>A0A523YK60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccales archaeon|TrEMBL
MKSESNLEKVLEAGKFAVTSEIGPPKSADGNVVRKKTGILKNFVDAANITDNQTAIVRLS
SIAAASILLQEGIEPVAQMTVRDRNRIAIQSDILGAAALGVKNVLCLSGDHQKFGNHPSS
KNVFDIDSMQLIRMLKDMRDAKKFQCGDEMDVEPRLFIGAAANPFADPFEFRVHRLAKKI
DAGVDFIQTQGIYDINRFEKWLEEARSEGLTEKVYILGGVIPLKSAGAAKYIKNKVAGMI
VPDSLIDRMKNAADPKQEGIKIAIETIEQLKDMKGVHGVHIMAIEWEEKVPEIVKESGLL
PRPSV
>A0A826L1W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O6|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2E7MC20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MPLDETMTETFKEALHQRALLADGAVGTEIYRRGVFINRCFDELSLSQPDLIRSIHEDYQ
AAGADIITTNTYGAQELRLGQYGLAEKQESIVRAGVRLAREAAGPECFVAGSMGPLPHLI
KPSGPISAATARENYRQQAELMLDEGVDVFVLETFRQLGMLEEAVGAVRAVSSDIPIIAS
FAFKPVRHYFVGPTPEEVSAAVATWDVDVLGTNCVNGPQPMLEIVERMQVSTGIPVCAMP
NAGQPEQVDGRTLFLASPEYMAEYARRFVQAGVRIVGGCCGTTPEMTREMRSFLESVEPK
RRRIEVKPVAPRQAGIMDEQPLPMRSRWGSRIGNEFAISVELDAPRGLDASRCVEGAQLL
ADHGVQAINIADGPRATARMSALALAMQVESAVDIDVIVHYCCRDRNLLGMQMDLLGAHS
LGIRNVLCVTGDPPKMGNYPDATGVFDLDSVQLVRAVRNLNCGIDFGGDPMGEQTQFVIG
CGCNPAYEPLEHEVEKFRRKLEAGAEFVFSQPLYEPAILERFLEAIRPFPHIPFFVGILP
LASSKNAEFLHNEVPGMSVPKPIRARLAKAAGRDAQRREGIAIAADTLRHARSLEGISGA
YIFPPFGRYSAVLDVINLVENAEVRAEI
>A0A7V3DJ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSLRFREILSSGEFVITSEIGPPKGTNLAPMLHHIELLKDKVHALNVTDHQSSVMRFPSL
GGAMLIREKGGEPILQMTCRDRNRLALQADLLLAYSRGIRNVLCLTGDSVVVGDHKEAKG
VFDLDSSQLLMAVRSLEQGKDLGGNELDGKPEFCAGAIVTPEARPLEPQLIKFEKKIQAG
AEFFQTQAIYDLENFERFMDYARPFGVKILAGIILLTSWRMAEYMNKNVPGVYVPQHLIQ
ELKEAPKGEALGVGIQIAGRMIKTLKEKRLCHGVHIMAIGREELVPEILQAAGLDGTGG
>A0A7V0JRP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MISGSNLEQVLTSGQFTVTGELGPPQNGNFDVVRDKARILKGHVDAVNITDCQTAIVRMS
SLTAGLVALAEGVEPVMQMTCRDRNRIGIQSDILGASALGIKNLLCLTGDHQKFGNHPQA
KGVFDMDSIQLLGMVKAMRDDKKFQCGDEIKSHEPRLLLGAAANPFADPFE
>A0A3A4NVX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKKAPLVFDGAMGTVIYDRGVFINSCYDELCLTAQKLILQIHRDYVEAGAEVIETNTFGA
NPIKLKPYGLSDRTEEINRAAVRLAREAAGKGIFVAGSVGPCTESNQRMPDAFAAEAEGA
FRAQMTALAVEGVDLFLLETFSNRNELQLAARVAKEFGGPVLASFVLNERGETSLGTKAE
AMASALNADPHVDIVGINCGTGPSGTFDALQAILPHTVKPLVVMPNAGLPREISGRVMYL
TSPEYFTEYAKKYIELGVRGVGGCCGTTPAHIRTMARAVKTLSGVKRHVEVKPLLRQETL
VYAVPPERKSLLAEKLLAGRKVTSVELLPPKSSDMTALLAKARQCAEAGIDAINIPDGPR
ASARVSPMIAALTIHREVGIEPILHYCCRDRNLIGMQSDLLGGYAAKLANFLIITGDPPK
IGDYPDVTGVFDVDSIGLVQVASNLNRGVDIGGNPIDPPTGLFIGVGANPCAVDLEREIE
RYFRKVDAGAEFAITQPVFDPEALLRFLDRVGSYPRTIPVLAGVWPLVSFKNAEFMNNEV
PGVVVPKAILSRMERCRSREDARKAGIDIARGIVGKIADRVGGFQVSAPLGNVETALAVL
GKPSA
>A0A4R6ZM69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria rocourtiae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLEDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARIAAPSL
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIVANVSMHEPGLL
QNGQTLASALQELADLGADVVGANCRLGPYHMSKALETVPLLENAYLAAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRRGLNSLEPVTSKVVHPIL
ELAELDVAEDTGVRLTDKVKEQYTVLVELDPPRTFDTAKFFEGAQELDAAGVDAITISDN
SLATPRISNMALAAILKHEYDIRPLIHLTTRDHNLIGMHSHIMGFHKLGIQDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALVEAGITVPVFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREADKTGAGCEEGMAIAKEILDSICAHFNGVYIITPFLRYDLSIE
LTKYVQNKEQIVEISSQN
>A0A840E060|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus voinovskiensis|TrEMBL
MGLLEDVKERIVLADGAMGTLLYSHGIDRCFEELNISKPEEIVHIHEAYIAAGAEVIQTN
TYGANYVKLSRYGLQDDVQTINRAAVRLAKQAAKGSAYVLGTIGGLRSVNKSAITLEEVK
RTFREQLYVLLHEDVDGLLLETYYDLEELKTVLAIARKETNKPIIAHVTLHDVGILQDGT
PLSEALAQLEQLGADIVGLNCHLGPYHMIRSLEEVPLPTTAFLSAYPNASLPDYRDGRLV
YETNAEYFKETALAFRHQGVRLIGGCCGTTPSHIEAMAKALTDRTPVQQKQVKQRTLSVS
VSAPPEQTEPPLTDIVRKRRSIIVELDPPKKLGIEKFLEGAKALKEANIDALTLADNSLA
TPRISNVALGTIVKQQLGIRPLIHITCRDRNLIGLQSHLMGLYTLGITDVLAVTGDPSKI
GDFPGATSVYDLSSFDLIQLIHQFNEGVSYSGQPLGQKTKFSIAAAFNPNVRHLDKAVQR
LEKKIQCGAHYFMTQPIYSEKQIEAVYDATKHLDTPIYIGIMPLTSARNAEFLHHEVPGI
TLSDDIRARMAACANDPIQSAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYEMTVELAQY
VHEKQAANERKVLHG
>A0A7D7LHF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc edaphicum CCNP1411|TrEMBL
MHHTHSHTAFRRAVQAGEFLVTAEVAPPKGGDPAHMIQMAATLKGRVHAVNVTDGSRAVL
RMSSLMASVILSQNGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALTGDPVKAGDH
PDAKAVFDLEAVRLLQLIRKMNQGVDCNEKPLTDGALDLFVGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFEQLEKFMDTIAAGYKKPILAGIFLLKSAKNAQFINRCVPGVN
IPQHIIDRLAKAKDPFEEGIKIAAEQVQIARQLCQGVHMMAVKREDAIAPILDLAGVAPL
NQLVSK
>A0A7C3P0Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSNLEKILTKGLFAVTGELGPPKGNDISVVKRKADLLRGYVDAVNVTDNQTAIVRMS
SIATSSLLIQMGLEPVMQMVTRDRNRIAIQSDLFGATALGIKNMLCLTGDHHTFGNQVDS
KNVHDLDSIQLIDCVRTLRDQGTLLGGEEKVEGQVKMFIGAAENPFGDPFEFRAVRLGKK
VAAGVDFIQTQCIYDMKRFKEWMKMVRDRGLHERVHILGGVTPLKSGGMARYMAKNVSGI
IIPDEMIDRIVKAKKPAEEGIKLCVEQIQELRE
>A0A7V7CR30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSDKIETKTPSKLEAVLASGNFAVTSECGPPRGSDPEVIKKKANLIKDHVDAINITDNQT
SVTRLSSFASCIHLKLMGLEPILQMVVRDRNRIALQSDILGAASFDIHNMLCLSGDHQQF
GDNAQGQNVFDLDSMQLIQTVRRMRDEGKFLGGDDIIRPPRLFVGAAANPFADPFEIRVP
RLAKKIAAGAEFIQTQCIYNLEKFELWMKLARDRGLHEKVYIMGGVTPLRSAGMAKYMKN
RVPGMDVPDEVVARMAGVPKEKQAQEGIDICVETIQRLKECEGVRGFHIMAIEWEEKVPE
IVERSGLYPRPSHS
>A0A2N6BCB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTEFYSKFQESLLDKDTFSITWELVPGRGSFEVAQEVVFSSAEEAAKGGKVHALTITDNP
GGNPAISSEMLGAEIIKMGIEPLVHFTCKDKNRNQLEGLLYGMERENVHNLLVMTGDYTY
SGFRGRSKPVFDLDPAQLLSLITEMNQGLVIPTFKGTATLKPTHFFAGAAVSPFKAVEAE
QMGQYYKLKKKLDAGAQFIVTQLGYDFRKIQEAKMMMDTLGYGNVPIIGNIYLLPLGAAR
LMNRNGLPGCVVTNELVDVIAKEAEAEDKGKGKRLERAAKMYAFMKTQGFAGVHIGGHGM
KYDDVEVIIQMGEELLPKVDEFVKEFDFSQPDGWYYFEKDEATGLNTSTPTDRSDKPSAS
LGYKTFKVLHHSMFEKKGFLFGPMRAISRAIDGSGMEHFFTRVEHFMKVMTNE
>A0A7V7D332|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTGSQLKRVLENGEFAVTAECGPPKGADPEIVRKKGELLRGNVDAVNVTDNQTAIVRMS
SLAACALLKQAGLEPVLQMVVRDRNRIALQSDVLGASALGIRNLLCLSGDHQVFGNQPDA
IGVFDLDSMQFLQVVKGMRDKGVILGNDALQTSPDLFIGAAANPFADPKEFRVVRLAKKI
KAGADFIQTQCIYNLDRFEAWLSMARDRGLTEKVFILGGVTPLKTAGMAKYMKTRVSGMD
IPDEIIRRMEGVPKEKQREEGISICVETITRLKELKGVNGVHIMAIEWEEAVKEIAERAG
LLPRPVFGEG
>A0A7V4PKK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRTRSNVERILESGGFVVTSECGPPRGSDGEVIRRKGEWLRGVVDAVNVTDNQTSVVRMS
SWASCLILKGMGFDPILQVVCRDRNRIAIQSDLLGAAALGINNVLCLSGDHQRFGDHPRA
KNVFDLDSVQLIQAVRVMRDEGRFLSGEELRGRPLLFIGAAENPFADPFEIRALRLEKKV
RAGAEFIQTQCIYNVERFERWMGMVRELGLHERCAILAGVTPLKSVGMARYMKTQVPGMD
VPDEVIDRLKGVPKERQAEEGIRICVETIQRLREIPGVRGVHIMAIEWEEKVREIVEAAG
LLPRPQPTETQEQRT
>A0A661NPJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
NMDKFKTWMGQVVDRGLHEKVHILAGVTPLKSLGMARYMAKNVSGIEVPGELIKRIKGVS
KEKRAAEGIKICTEQIQQLREIPGVAGIHMMAIEWEHKVPEIIKGAGLYPRPRPPDEPS
>A0A661RW52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTSLFLNNDEFTITIEVVPPTGNDPATILKKLTSISDLSFHGFSVASNPVAKPKMSAMVF
THLIQKATQKPAILHCTVRDHNRLGLQSELWGAKALGIDTVIAVTGDPSAFRAEEPTSTV
GDLNVCQLISMARDSDLFTGAVLDFRPEFNGLEHETKRLAKKVASGCRFIVTQPIYDEET
AKEIHEAVKHLNVPVIMGILPLLSYKHALFLHDKVAGIAVPEPLRKRMEEAQDPAKEGVS
QARQMLELAKKMFSGACIMPPFDRFEILPDILKS
>A0A2P5VK76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha1_Bin1|TrEMBL
TYGAGGSTRQRTHDTVTRIQNEGGLPCAAHLTCVGASRDEVNQIAQNYWNAGVRHLVALR
GDPPEGQVEFQKHPDGYYNAAELVSGLLQLANFDISVAAYPEMHPDSPSSQADLDNLKRK
IDAGANRAITQFFFDADTYLRFLERARAAGVWVPIVPGILPVSNFVQAARIAKSCGTVMP
AWMAHLFEGLDDDIETRRMVAVTVAAEQCRKLRTAGVTDFHFYTLNRADLTYAICHILGF
RPPYVGPGASSK
>A0A661MPY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MASKFRKALESGKFVVTCEIAPPKGTNLKKMLHHVELLKDKVDAINITDHQSSVMRFPSL
GGALLVKESGGEPILQMTCRDRNRLALQADLLFAYTRGVNNVLCLTGDSVIFGDHKEAKG
VFDLDSSQLIMAIRKMEKGKDLGGNDLDGEMEFCVGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVYDLDNFKKFMEYASQFPVKVLAGIILLTSAPMARFMNKNVAGVSVPQNLID
EMASAPKEKAIDKGIEIAGRMVRRIYEEKMCHGVHIMAIGREELVPEIMAAAGLI
>A0A496ZJ44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSFQKRLSAGKFVVLAEMHTPKGVNISKMVLDSRRIKGRVDAVIVPDMDNGVMKMSALAG
GVLMHQQGLETIIHVYTRDRNSMALQGDILAAHVLGIQNLVVVHSEDMANGDHRDAQPVY
EVDEPGLLEAIQTLQSGKDLAGFDLDGVPSFTSGCAMGSFANDADMESELQLAQKKVAAG
AQFIITPPVFDVEIFADFMKKTTGLGVPIIPTVFLIKSVAIARYIAKSEPEAHVSEAMIK
RIRKASDREMEGIKIAGETVKALSKIAQGVKIQTLGWEHRLPQILDVAGL
>A0A353EQ18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNFTDFYKPGTCRYSFEVFPVKTEEGVKNLLQVLGELKDFDPAYVSVTYGALGSTRDLTR
DLALRIHRGTKIPTAFHFTCVGSGRQEIKNYVEKLKKEGLNLVVALRGDPPKGGAFIPPT
DGFRYANELVTYLKSINGFSMAVAGYPEGHPEAGSKEADLVNLKRKVEAGADAVITQMFF
DNRDYFDFVERAHKVGISVPIIPGIMPILNLKQIEKITGLCGAKIPSQLHQRLVQCGEDV
EATRNVGIEHALKQCHELKKSGVPGIHFYTLNKSLSVAGIIENL
>A0A432HKI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNVKTPSRLEKVLATGQLAVTSECGPPRGSDPEVIVNKANMIKDYVDAVNITDNQTSVTR
MCSLAACIRLKQMGLDPVLQMVTRDRNRIALQSDILGAASFDISNILCLSGDHQSFGDNP
QGQNVHDIDSMQLIQVVRLMRDEGKFLSGDDIKRPPQMFVGAAANPFADPFEIRVSRLAK
KVKAGAEFIQTQCIYNLDKFEEWMKGARERGLHEKVHILAGMTPMKSAGMAKYMRNRVPG
MDVPDEVVKRLADTPKEKQAEEGVKMCIEDILRLKEVEGVAGFHIMAIEWEQIVPEIVKE
AGLYPRPDVA
>A0A496YQF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
GSGIESGWGKDVPDLEMKEMERMAKIGAGYFLTTPVFDLDMFEKFVKQVETFGIPVIAEV
MILRTAGMASFLNRHFKSGLVPDWMIKKLAKAVDKEKASIEIFADTVKGLKDLCQGVHII
TIGGEERLRYYLDAAKLR
>A0A509LI09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNLKESLEKKRFVVTSEVQVPMGDEEPEVIVDSLSKVKGRVDGVSVSEIELEGVVSDTIK
TCGLLKDNNLNAIYQTTTRDKNRFQLQKDLTLAHETGVENLLVFTEDYRISGDTLQESMF
FHVDSGKLGSVLDHMKQGVTIEGNELENKMDFVLGSGIETPWGKNMPKRGMEEMEDMMNV
GTGYFLTTPIFDVDQFARFMKQVEPFRVPVIAEVMILRTAGMGKFLNRHFKSGLVPDWVI
QKLAQSPNKKKASMELFADTVNSLKDICQGVHIITIGGVDNLVQYLNAAKLR
>A0A661LZG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MVSRFKDALESGKFVVTSEVAPPKGTNLEKMKHHVELLKDKVDAMNVTDHQSSVMRFPSL
GGALLVKEMGGEPILQMTCRDRNRMALQADLLFASSRGINNVLCLTGDSVILGDHKGAKS
VFDLDSSQLLAAVRQLEKGKDLGGSDLDGGVSFCAGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVYDLDRFQKFMEYARQFPVKILAGVILLTSAPMARFMNKNVAGVTVPKELID
EMAAAPKGRGIDTGIKIAGRMIRRIRDEKMCDGVHIMAIGREELVPAIMEAGGILS
>A0A5C6ERY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubripirellula reticaptiva|TrEMBL
MSLISHYEGASCAISFELFPPKTEEGMEAMADNVRRLCEFNPSYFTCTYGAGGSTRGTTL
SVLKKVREITNLPVASHLTCVGSTVAELDSYLNEATEQGVDYIVALRGDPPKGTDKFVPV
EGGLRYANELVEVINAKFSKLGIAVAGYPEVHQESPDAKTDLENLKRKVDAGADIIITQL
FYDNIDYFRFRDRCVAAGINVPIVPGILPVTNFKQAQRIAAMCKASIPYELEQSMNSHDD
AGDQFRIGVDHARKQTINLMEHGVPGIHYYVLNKSDAATALLDGLQMVS
>A0A661LM26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTLEKKLEEKAFAVLAEFEPPKGADFSEMLNNAVNVKGRIDAFVVPEMASAVMKASSLGG
SLFLQINGLETVVQVCCRDRNRLALQADILSAAALGIRNLMVVKGDDIAVGDHPQARAVN
DLDLFELLDVIKQLQAGKDMAGIELKGSPRFLVGSTFNAGAQGGLLDLEFDELEKKAASG
VKFIITTPVFDLKILERILKRLDTTKIALIPKVLLLKSAGMARYMNRNIKNISIPEVFIK
SIQRAPDKPQECIKIAAELIRQIRKLGLPGVVISTIGWEDKLPQLLDESDIS
>A0A661SC85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLTELFDKGEFVITSEVGPVKGCLRSGSGDEPPQCAREAEMVRECVHAINVTDNQSAVM
RLGSLAASVKLRGKGFDPIYQVTCRDRNRIALQSDLLSACSLEIDNVLCLTGDYTSLGDH
KSAKSVFDIDSVQLLKIAKGLNEGHDMVGNTLTKSTDLALGAVVNPNFEPLDLQLFKMEK
KIEAGAQFFQTQAVYDPAVFERMVKKTEGFGVPIQYGIVVIKSPQMGKFMNKNISGIMVP
DRIIEAMGSVSKEDRKKKAVEITTELVREIAPMAQGVHFMPLGWSDIVPTVVEAIKGTVV
>A0A379FXJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia rettgeri|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSEEMEQTLWKSIDRLKNLKPKFVSVTY
GANSGERDRTHSIIKDIKDKTGLIAAPHLTCIDASPDELKAIARDYWNNGIRHIVALRGD
LPDNSRKPDMYAVDLVELLKGEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPAWMSKMYE
GLDNDPESRNLVGAPIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A1Y4IHI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp. An196|TrEMBL
MKITELFERGEFVVSAEVGPPKGFHVEHLLEEAKTYLGGITAVNVTDNQSSVMRLGSLAM
CKALKDEGLTPIYQLTCRDRNRIALQSDLLSAAMFGIENLLLLTGDHTSLGDHPQAKPVF
DLDSVSLIHAVKQLEEGVDLGGNKLVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVCAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNDNVAGIHVPDEMIEE
LKKDKEKTKAGITGVEIAARIIKECRPYCQGVHIMALGWESKVPELLKQAGI
>A0A3N5T079|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNAGSQLEKILRQGRFAVTGELRSPQGNDVSVIKRRADFLRGSVDAVHVADNQDAIVRMS
SLAVSSLLLRMGLEPVMHLSTRDRNRIAIQSDLFGATALGIQNLLCLTGTHPSLGNQVDS
KNVYDLDSIQLIDAVSGMRDRGTLLGNGEKIEGEIKVFIGATANPAADPLEAHVIRLAKK
VK
>A0A496Y9M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MPIDDKIQSGEFVVLGEFEPPKGADFSPLLANANLVKGRVDAFVIPEMANAVMKASSLGG
CCFLQTHGFETVLQVSCRDRNRLALQADILAAAGIGISSVMVVPGEEIRYGDHHQARAVY
DVDLMELLDGIGRLQEGKDMAGIELQGAPRFFVGTTFNAGATGGAMGLELEELQKRVDKG
VQFVITTPVFDVAGFQQTLSRMEGLGAAIIPTVLLLKSAGMARYIDRNISHISIPSDMIQ
SIQKAPDKVRRCVQIAGELIAQLKQLGVAGVLVSTIGWEDKLPQVLDIARV
>A0A2E1RA90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
HNIRWSMEILPQNIVNASFIPAFINEVYITMIPGRAFRETIEAAEQIRLIGKQAVPHISA
RGFTGTXDLEKCLSGLQAAGIERALLIGGGHSEPAGNINCVMXMLKTGLFAKXGINSFDF
AGHPEGNPDDPNSEFNLLEKLSWAKEHRISARIVTQWCFDTEGTNAWISRLRQKGVKNPI
HLGIPGPSTLKTLMRFAKVCGVSASTTVLRKYGLKLSKLMFVNKPDKIISDLRGYDQLHL
YPFGGIEKSSEWLHEWQQKD
>A0A0X8HWC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eremothecium sinecaudum|TrEMBL
MSTIRRIYDESSGPTISLEFFPPKTASGKSNLLARIERMSAMNPLFLTVTWGAGGSTAEK
TLELAALVQRVINIPVCMHLTCTNMDKDVIDYALQKAKDADIRNILALRGDQPIEQDSMA
EGSGEFKYAVDLVRYIKEKHGDDFCVGVAAYPEGHCEGEANEGEQDVMRDLPFLKQKIEA
GAEFVITQLFYDVEKFLSFEAIFSSQISATVPLIPGLMPINSFLLFNRAAKLSHTSIPES
ILDRFPHHVRGDDLKVREIGVDIMVDIVNKIWERTSGRVKCFHFYTLNLEKSIAQIVTRS
PVLSKILEDDSEAESQCNEQEDIVITDADGIANTIDNIKKRRRRSSIQNGDVANRVLVDE
HSSANFNRKGNGAPSRKVVVAISQGSGSLGRHATWDEFTNGRFGDSRSPAYGEIDGYGPS
LKVSSNAAYKIWGQPSCIEDLINIFIGYLDSSIEKLPWCDLGISSETALIQEELIELNKR
GYLTLASQPSTNSTPSADKIFGWGPPGGMVYQKAFVELFINKETWEQVIKPRIDASESYL
SYYVGDSSGNFQSNMEPESSSVVTWGVFPNSQILQTTIIEEESFKAWNDEAFKIWVEWSK
LFPRNSPSYSLLRQMHRDYYLVSIVYHNFTDFDGLWNLLLS
>A0A7W9KL86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kutzneria kofuensis|TrEMBL
MTSVVERLHGPDPVFSVEFFPPRDEADEQRLWLAIRQLEGLEPAFMSVTYGAGGSSRDRT
IRTTGRVVQETSLLPMAHLTAVDHSVAELRNVIGWYAAVGVRNILAVRGDPPGDPNGEWI
RHPQGLTYAEELVALVKQLGDFCVGVAAFPYGHPRSTDLDSDTENLVRKFRAGAGFAIAQ
LFFEAEDFLRLRDRLAKRGCDAPLLPGILPLTTVRTLRKTVELSGAPVPPSLARRLDPLV
DDPKAFRAEGIDIVTELAQRLIDEGVPGVHFYTFNMSKATTEVVERLGLHRPAHDRSAG
>A0A7T1I5T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. CBW1006|TrEMBL
MQQLHQALTQGHFAVTAEVTPPRGGDCTRTLEAARALRGLVHAVNVTDGSRAVMRMCSLA
VCRLLLDAGIEPIWQVACRDRNRIALQADLLGAHALGIRNVLCLTGDPVRAGDQPEARPV
NELESVRLLQLVSLLNSGEDPVKGSLPDGPTQLFAGAAADPQSPSWSGLRSRLQRKQEAG
ARFVQTQMVMETDALRRFVDELAAPLGLPVLAGVFLLKSARNAAFVNRVVPGARIPQHLI
ERLADAADPAAEGIAIAAEQVRAFSTIAQGVHLMAVKAEERIPAIIRQAGLGPLGQGQVG
AEKVGHGLLLG
>A0A1D9CWE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. AntiMn-1|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALSA
RSETEIAPHMSCIGDDKAQIAELLEFYKSLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
FIREYSGDHFHIEVAAYPEMHPQARSFEFDVDNLVNKYRAGANASITQFFYNADSYLYLR
DTLEKRGIDTIAQPLVAGIMPITNSSNLIRFADSCGADIPRYVRKQLADFGDDSKSIREF
GFDVVYRLCERLMSEGVPAMHFYSMNKVEPNKRLVEALGLTV
>A0A0V0TNN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella murrelli|TrEMBL
MFCDDIVYNQLYRVAKVGNPSQQTDFGVYFEEDSFLSLMASLEAVELKATRHDLNSAAKK
STDEIYRPLIDRIKENISSGRRFFSLEFFPPHTTEGLINLLKRVDIFANSQPLFVDVTWV
MRSDPASEKVTSSSSLADCILNFCLLDTMLHITSVQYDEKTVLFNLERAKKIGIRNILAL
RGDISDDANVTTTDFQYACQLVRFIRSHYGDYFTICVAEDLLNLKAKVDAGADFIITQLF
FNEMHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSKIVIPDSVLTTLESIKEN
AEAVRNFGISYAVQLCRKLLNREHHVVPGLHFYTLNQEKSILEQIGFWKKAPVRMFPWKK
HTVHSVRCREAVRPIYWTARPKSYLCRTRDWKQFPHSRWGDVGNPAFGDLKHYLFSCIDQ
MDDSCALDMWDKELSTLEHVRDIFCNFIARTPNRHGHSVRRLPWNENHLDPAADVLKNEL
IYYNSNGILTINCQAAVNGLPSSDPIFGWGEANGYIYQKGYLEFFASSTCTTILLNHVQN
FPSINYHAINFDGSFETFNYDEDATVALTWGVFVGQEIVQPTVANAASFRVWKVVAQLSF
IQLFLFVFEQDEAFDLWQRWAGLYESGSIGRKLLQRIHDDYRLITLIDNDYPQPCSLSAL
LRAVISDYIGGKNLTTDDDRLACKKKQCVRECVRACAYVENSGRLALRASKHGITAEKEE
EEEEEAIIE
>A0A1M4J4T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas translucens pv. graminis|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQASDALSDLRHFKAKVDAGADGAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQALGDDGDAIREFGADLV
AALCQRLLAGGAPALHFYTLNLAKPTVGVLSRLA
>A0A520S475|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoricolaceae bacterium|TrEMBL
MKTFDPKGKPKSWSIEITPKESKTISCFSTFLDCDTKVNVTNLPKTSVTDIFATVEKLKH
DGMNPVPHITARTVIDEDDLARIVEKYATLEVSEVLIIAGNKFQPAGSFSSSSDLISSGV
FEHFGIINLGVAGHPEGSPDITQQQLEDAIDQKNHLAASRGLNIFLETQFCFDAQRIIDW
EKAIRDRGNSLPIRVGVAGPTKLLSLINFAIKAGVGPSLKFLIKERDKLTKLVHSYDPTD
LILSLAPQFSPEANTCLESIHFYAFGGFRKTAEYAQELFK
>A0A428IHG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSHQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHNPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A644XTB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MHITDIFNKKKFVFSFEIFPPKATSSIETIYKTLESLSDLRPDYISVTYGAGGGNNQNKT
REISSIIKNKYGIETMAHLTCIRSTGEEIIDTLRDLKKEGIENILALRGDIPLEEEVKGD
FQHASDLAEFIMSRDNFDLGGTCYPEGHVDCKNLEEDVKNLKFKIEAGVTHLTTQLFFDN
NDFYNFLNLAEKHNINVPIQAGIMPLTNKSQIERIVTLSGSKIPEKYIQIMNKFEYDKDA
MADAGIAYASEQIIDLMANGVDGVHLYTMNNPYVARKTHNNIISLVHSLNREI
>A0A4Q2FMU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A139QQK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MQELAPHFISVTASNNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADL
DKVGVQKILALRGDIIPDVEPQKDFRYATDLIEFIKEQAPHFEIVGACYPEGHPDSPNQI
SDIQNLKKKVDAGCSSLVTQLFFDNERFYDFQDKCTLAGIDVPIHAGIMPILNRNQALRL
LKTCENIHLPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNAET
AKYIHQATHALFNHQSLG
>A0A0F3IVG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elstera litoralis|TrEMBL
MSDSLAISFEFFPPKTPEMEASLWSAVEKLAPLNPSFVSVTYGAGGSTRERTHATVRRLR
QETKLEPAAHLTCVAATREDIDAIARDYWASGIRHIVALRGDTPTGGPYEPTPGGYGYST
DLVAGLTRIAPFEISVAAYPEGHPESKSLDADLDVLKRKVDAGATRAITQYFFETDLFVR
FVERARKAGISIPIVPGILPVTNVAQVLKFSKACGTSVPQWLADTFDGLDADPETRKLVA
ASVAAEQVLKLKAEGISDFHFYTLNRADLTLALCRRLGVRAPAAA
>D8U7H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Volvox carteri f. nagariensis|TrEMBL
MKIINKINQKLKDGQTFFSFEFFPPRTEEGVENLFERLDRMVAYGPIFCDITWGAGGSTA
DVTLDIATRMQNQVCVETMMHLTCTNMPVEKLESALLEVKKAGVHNILALRGDPPKGQDK
FEAVEGGFSCALDLVKYIRKEFGDLFGICVAGYPEAHPDGIVDDPELMEQNYWADIAYLK
QKVEAGGELIITQLFYNTDIFLKFVEDCRSVGITVPILPGIMPIMTYGGFKRMTGFCKTK
VPADILEAVEAIKDNDEAVKNFGVDLGVRMCRRLLDAGVPGVHMYTLNLERSAVGILERL
GLIDTARVPKPLPWRHVPTGTARAAESVRPVFWSNRTKAYLKRTQGWPSYPTGRWADRGA
LQYGSLADVPQYMRRHTSTDARKERARAAWGSSLESEDDVKAVFAKYFKGEVKLFPWSEV
EGSPEAAAGEEALIASGYLVINSQPKLNGVPSTDSAHGWGAPGGTLYGRAYLEFFCSPAA
WESLRARLDAAPSVSYLAATAAGSPQGNLKPDDVVALSWGAFPGKEIVQPTVLCASSFGV
WKDEAFELWLSEWAGLYEEGSPSRQLLTGIHDNWVLVCAVDNDYVAGDLAKVLLG
>A0A2W2E8M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora craterilacus|TrEMBL
MALGLPSVLPNPQPAIGELVRDCQPTFSFEFMPPKTEQGEQQLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRHVIGRLAGAGVRNVLAVR
GDPPGDPTGEWVPHPAGVHYAEDLVRLVRRSGDFSVGVAAFPYRHPRSPDVATDTEHFVR
KCRAGADFAITQMFFDADEYLRLRDRVVAAGCDTPILAGVMPVTRIGTIERSVQLTGAPF
PPALAARFEQVADDPDAVRRLGIEQTSEMCRRLLDEGVPGIHFITFNRSTATREIWQNLR
VGAAT
>A0A7Y2GAY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermales bacterium|TrEMBL
MKITELIDRRKETLISYEIIPPERGGSAGEIFEIISSLMEFEPPFIDVTSHAAQVYYEEM
PDGSWMRRIKRKRPGTLGLCAAIKGRFGVEAVPHLLCHGFTRQETEDALIELNYLGIQNV
MALRGDNHGYEKTFPPDKSVNKQAVDLVAQISSMNHGRFLEELIDADPTDFCIGIAGYPE
KHFEAPNMAWDVLHLRQKVDAGAHYVTTQMFFDNRHYFSFVDRCREAGVDVPILPGLKII
TSRKQLKSLPSRFALEIPEALAAEIEAAADEHVAEIGVAWAVEQSRELIEAGVPCLHFYI
MKTARHVKEVVSRLRKLA
>A0A7G2D115|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Nx66|TrEMBL
MLFVVRGPRPLSPGEKMSSPFDASHASRVPFSFELYPPRSESSQEALHETVRHLAAAGPA
FLSVTYGAGGSTGGRSLDVLRFIREHTDVEPLAHLTCVGNTYAGATALIREFLDAGILRF
LALRGDPPAGRTEPFLGDLESAAQLVQLIDRVQAERAPYQESPVPGLPGAALVAPRQKVD
IAVAAFPKGHPRATHRTQDVEALLAKQAAGATFAITQLFFHPDDYLAFVERARAGGVTIP
ILPGIMPITSPARLARVLELTGEDLPSELSVALDVEPTAEGRREIGISWAARLAADVVAG
GAPGVHLYAFNQHETVLTVLAEAGIVPALRH
>A0A6P0JCF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO4A5|TrEMBL
MTNPTKNSFRTAVESGEFLITAEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQQGIEPICQVACRDRNRIALQADLMGINALGISNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFEK
KLEAGAEFFQSQLICDFDRLEKFMDQIAAGTNKPILAGIFLLKSAKNAKFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSAINDLVCK
>A0A8J5CY65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chionoecetes opilio|TrEMBL
MDGQMARWAEYFGQFFTVDPPIEQLHTTGLWAVDADPPIDETAPSLDEVREAVAKLRGGK
AAGVCNISAELLKAGGKSTTDRIVALRVLVERRREFRQGMLAAYVDLKKAFDSVHHESLW
DLLRLRVIPARTVGLMIGLYSGTESAVKCGEVVFFPVNTRVRQGCVLAPSLFNTCMDWVL
GKVVDQSDCGASLGNTKITDLVFADDAVIFAESLQVLVMALVALHEEAKPLGLEVSWLKT
KVQVFGGLLDETVVCSCMFDRMREGDPLFCDVTWHPAGNPGGDTETSSLTIAVPTKKALR
NTAPLHVSSGDLATTSNPDSGVPLPPGVPSPGVPLPPGVPSPGVPLPPGVPSPGVPLPPG
VPSPGVPLPPGVPSPGVPLPPGVPSPGVPLPPGVPSPGVPLPPGVPLPPGVPSPGVPLPP
GVPSPGVPLPPGVPSPGVPLPPGVPSPGVPLPPGVPSPGVPLPPGVPSREFHCLREFHPR
EFHCLREFHPREFHCLREFHPREFHCLREFHPREFHCLREFHPREFHCLREFHPREFHCL
REFHPREFHCLREFHPREFHCLREFHPREFHPREFHCLREFHPREFHCLREFHLREFHCL
REFHPREFHCLREFHPREFHPREFHCLREFHPREFHCLREFHLREPQSLPRLGNQQLGLH
LELLPQKLHDVTQRGAALNYCGLETMLHMTCCSMSKTEIFRHLQRAKEVGIRNILALRGA
EALLALYKDGDIEKRALKLHRQFGHRTAEKLKKLVRDADIRDSNLERRIDKVTSDCDVCK
RYKKPSPRPVLSVPLASRFNEVIAMDLKSWGKKYFLVIVDLYTRYCTSVVVPDKNAGTII
RGIFLGWVVLFGAPGKILLDNGCEFNNSDMRSLGEAFNVKIITMAAENPWSNGVCERLNA
VLGGMVSKILADFPGCDLDVALAWAVAARNALSKFSGYSPNQLVFGQNPGIPGAFYDNLP
ALDGEDTPAGIVKDNLNALHAARRAFTVAESSERLTRALRHNVKDSDPGDLHYGDDVYYK
RLDSNKWRGPGTIIGKDRKQFLVKHGGMCVRVHTCRIATAPTSVDPAAVSNEEDVSQSNT
SALQVPSVRGDVKLGFGDSDMDSDDDDHPGEIVDVVGEGAQVAMDGHNGDVRQTDTGASA
SGVLAIPVVRVKAGQRIKGVEKASGEWISGRIVSRAGKATGRYANCYNIKSDKDGNINWM
DLDRDFTSWETVDEATEMLVLFNTDEVVCAKEKEIENWRTKEVYEEVENVGQQAISVCWV
VTEKLKEGKTIVKARLVARGFEEDTIGLQKNSPTCSKEAVGSFDFECFKHVGLNVVTTED
GGITIDQFQYEASLNPVALSKRRALEKTSDLSEREKTEYRGDMGLKGALSSFCATLIMYG
ALFTGSQGRFDGWSIQLLAAETLALLDGASTVVYVASILQEISGCGRIPIRCFMDNRSVV
EALYTYKLVDNKRLRIDISVLRDMLDQGELKEVTWVETSKQLADCLTKKGASTMRLREAV
SRD
>A0A346YMN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neorhizobium sp. SOG26|TrEMBL
MNASREDFSVSFEYFPPKSDEMERQLWQAVEALSVWEPDFVTMTYGAGGSTKEPTLAAVS
RMVGEMHLPTAAHLTCVDASREETRAVIEDLRAAGVRRIVALRGDPATGIGTAYAPHPDG
YSTTADLVRALVEYGDFDISVSAYPEKHPESRDLAEDIATLKSKADAGANRALTQFFFDN
DVFERYLEKVRAAGINIPIVPGIMPIQNLAQLKRFARRCGSSVPAFLDERLEGLDEKPEE
RAEVAADIAAEQIEDLRRRGIHEFHIYTMNRVPLISAVMDRLGRGKARAPRTVAA
>A0A157ZYA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia pedi|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRASRAELKKLSPKFVSVTFGAGGSTQQGTLDTVLEMAT
EGFEAAPHLSCIGSSRDSLRAILLNYREHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQEHGDWFNIEVAAYPEFHPQSKSPRADLENFARKVKAGANSAITQYFFNADSYFRFVE
EARKLGVDVPIVPGIMPITNFSQLMRFSDMCGAEVPKWIARRLESFGDDRESIRAFGVDV
VTGLCQRLVDDGAPGLHFYTLNGAWASKAICEGLGFKSV
>A0A5K7ZT86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina ovata subsp. sediminis|TrEMBL
MSDNGYKSGSNLEKVLKAGHFAFTGECGPPKGANVEHLKEKFEHLRGKVDSVNVTDNQTA
VVRMSSAAASAIMVANGIEPNFQMVCRDRNRLAMMADILGVYSLGVRNMLCLSGDHQKFG
NHPQSKNVYDIDSMQLIAMVKKMRDEGKFLNEEDIDEPPRMFIGAAANPFADPYEFRIYR
LANKIDAGADFIQTQCIYNMPRFRDFMKQAVDMGLTEKAYILAGVTPMKSARMAQYMAKM
VPGMDVPEELIKRLQDAGKGKQAEEGIKFAIEQIEEFKDMDGVAGVHLMAIEWEHKVPEI
AERAGVLPRPQVE
>A0A455T9Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MKFSFEFFPPKNNLLEKKLYNTILKLNILNPYLFSVTCSSSSNSEELTLSTAKLIQKKTN
ITTAAHLTCINFDTYELKKIALNYWENGIKSIVALRGDNIIKTNNSSNMHASDLVTLLKN
VADFDISVAAYPEVHPEAHSPFSDLINLKKKIDNGASRAITQFFFNVDSYLKFRDRCIAI
GITVDIIPGILPILSFKQLKKFLSMTNICIPKKIYTIFEQTQNDHNVQKIIGSSIAIDLV
EKLYSEGVKIFHFYTLNNADTMCAIYHCLNH
>A0A3A1WUT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium NR047|TrEMBL
THLISQLFYDNEDFLRFRDLARAAGINVPIEAGVMPVANASQVQRMTSLCSSRITSQVSA
MMNRWGSNADCLRDAGSIFASQQINDLIAEGVDGIHLYTMNHPGIARRIWSNVKPLFTKI
G
>A0A258KYP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp. 32-62-53|TrEMBL
MVEGKERKSRLLGAGEIGVSFEFFPPKTEKMEEQLWTAINRLAPLAPEFVSVTYGAGGTT
RERTHATVERIVKETALRPAAHLTCVDATREEVNAVAQAYWNAGVRHIVALRGDPASGAG
QKYEPHPGGYVNAAELVAGLKKIANFEISVAGYPEKHPESQTLQADMDNLKAKVDAGADR
IITQFGFDNAHYLRFLERARAAGIWVPITPGIVPIHNFRQVAGFAVRAGATVPAWLARRF
EGLDNDPETTKMVASAVATEQVMQLVDEGIKSFHFYSLNRPDLVYAICHLLGLRPLHTAP
LEDRRIMIA
>A0A1N6QQ97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus thiocyanatus|TrEMBL
MPTPSISFEFFPPRNLDQSFRLWDTARALAPLEPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETLQIVQDYAAAGVHEIVALRGDAPQGQARFAPHPDGFADSV
ELIKAIAARGDMTIRCGAYPEPHPESPDTAADVAWLKRKVDAGASSAITQFFFDADTFFR
FRDACRAAGIAAPIIPGILPIQSWAGARRFAERCGTSVPQWAEDAFAAAGKQGEAQLALD
VCVTLCERLVEGGVDKLHFYTLNKPELVLKVCAALGIKPKDAVPRVA
>A0A7W6PSS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium rhizoryzae|TrEMBL
MDLRQDFTDSNLLPPRLIDNWSIEVLPRTAAKVPSFLDLLPTGTQIFLAHVDGTPLPSLV
ETARRLRNEGFSVTPHLPARSFTGRQELEDLLHRYRNEADITHALLLAGGATSARGDLLS
SFDLIETGLFDKLGFKQLHIAGHPEGNRDIDPDGSTRHVDAALLRKCEFAKRTDARVVIT
TQFLFESHSLLDWARRIETLGIDLPIHVGLAGPAKLQTLIRYAMTCGVGPSIKVLQKRAL
NLSRLLLPYEPTEMAQTLEAFKSANPSSRIERFHMFPLGGIEPAVHWCRQQMKA
>R5D9M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea sp. CAG:105|TrEMBL
MKIKDILKEKTPHISFEVFPPKTDAGFASVLSATDQIGALKPSYMSVTYGAGGGTSKNTV
NIASHIKDDLGLTSLAHLTCVSSTKEHVARVIDELKKNNIENVLALRGDIPKESEFPLPN
HYRYAYELVEEIKSKGDFCIGAACYPEGHVEAEHKKDDIYNLKKKVDCGVDFLTTQMFFD
NTIFYNFLYRIREIGITVPVVPGIMPVTKGNQMKRISEMSGTVLPQRFRDVLDRFGEDPK
AMQQAGIAYATDQIIDLFANGINHVHVYSMNNPAVATAIMHNLSDIVKNG
>A0A841R3I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Negativicoccus succinicivorans|TrEMBL
MKIKDKYEKEGPLYSFEVFPPKREGDLGNMVATLHELAQWHPDYMSVTYGAAGAARGMLT
LKLAEYIRKELDIEPLMHLTCVGYSQAELAEILARIEAAGIENTLLLRGDRREDGEMPAD
GFRYANELVAYVRSKHAFCIGAATYPEGHTEARSLTADLIRLRDKVNAGADFLVTQLFFD
NDAFFRFLETARSIDINVPISAGIMPCLNKAQIVRMTALSGASLPPKFRRMLDRYEHAPE
AMYDAGIAYACEQIIDLLSSGVDGIHLYVMNRPEVVQAVTRGIGRTLQTVKEEHRGTNAG
>A0A6S6W4K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenophora teres f. teres|TrEMBL
MEKITDKINSLPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCIGVAAYPEGHSDQSHPEHQDPLSDL
PYLVEKTKAGADFIMTQLFYDVQAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHARLPTEMLSRLDAVKSDDELVKQVGVQIMDEMVEHIKARPNSCRRGFHFYTLNL
EKTVSHVVEDTHLIPTTIMDDEEVIVETTPAINLEPPPNGLMAHRRRSSAVNSGPFNRVI
ISHGSGAKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGYPVEKKDISTLFRRHVEGDLEAIPWSEQGLSP
ETSTISAQLLALNAKGWWTVASQPAVNGVKSTDPIFGWGPKNGYVFQKPFVEFFIPASEF
QALKPKLQAHDQVTWFAGNAAGAFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIWKEWQRIYPPRSGSSVLLGDLSKDVWLVNVIWGDFVNGEGLWEFLGK
>A0A2D2HA46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas sp. FDAARGOS_362|TrEMBL
MNHVATPGAGASGASPGHDPGIHPGANPLGRWLTGPRFGALPAPAALPAPALSFEFFPPR
TEALENQLWACIRRLEPLAPRFVSVTYGAGGTTQARTHATVSRLVRETALTPAAHLTCVG
ASCGEVDDVARQYWDAGVRHIVALRGDPPAGAPDYVPHPQGYAYAADLVEGLRRVAPFEI
SVAAYPETHPSARSAEADLDNLKRKIDAGATRAITQYFFDTETFLRFIDRALAAGISVPI
VPGIMPVSNFNQMRNFSARIGASVPDWMAALFEGLDDDAETRRMVAAVVAAEQVRLLQAN
GVDEFHFYTLNRPDLTYAIAHILGVRPSRPADPASESGVEEEGKAEAASRQVGQAGA
>A0A6P8LZV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bombus impatiens|TrEMBL
MKKFVSKDKVHDPCIDDECDNNADHFRSVDTKREMIDLRKKLQDIIKTDAIFCSFEMMPV
ISKDLLQSFFTEMNKYHPLFYALTWHKNDMKDYLSLDIFNILPNNTLLHLIAKDLTSTDV
KIILKEALEHGIRNIFVLRGDSTKSNSEFSHAIDLVRFIRNQFGNIFCICIAGYPEMHPE
SSSKEMDLIYLKEKVDAGANFIITQIVFEASVFIKFVSDCKNIGINIPIIPGIFPILNYT
CLQKMARICNIKIPKIILNTLECIKDNDEEVHNYAVEIATNIIKKIIASKTACGFHFFTL
NKPSLSLEICDKLNIFH
>A0A7V8HRL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pullorum|TrEMBL
MSKPLFSLEVFPPKRTAPIGTIYDTLDGLRGVDPAFISVTYGTGKQSDRTITARIANTIR
TEYGIPAVAHLTAQYLDRDQTDEALDMFAQAKVAAVLALRGDRNPEREPAGVFMHASDLT
RYIRQTHPEMTVYGACYPECHPQSRDLDEDISWLKVKVDSGASHLISQLFYDNADYLRFL
DKARAAGIDVPIEAGIMPVTNAASVRRMTGMCSSKVPERLATILDRWGDDPNTLKEAGII
YASEQIADLVARGVDGIHLYTMNHPGVTRRIWQNVQGLF
>A0A496QTV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MGRFREALESRQEFITTCELIPGRGYKGRNVDQALQFASEVKDSPDIHALSLTDNAGGNP
ALSADVVGIEILNMGVDLIVHFSCKDMNRNAIESRAYLLARSGIENLLVLTGDYPIMGYM
GLPKPSFDMGAVNALYFLNNLNRGLEIEAGKRQVTLESTNFYLGAVVSPFKWTEASSVMQ
YIKLEKKIRAGAHFFITQLGFDALKHIELLKYVREYLGLDVPILGSVYVLSSGAARFMNR
GEVPGCYVNDRLLEKIKEESKTPDKGKEARLKRSARLVAVLKGLGYNGVHIEGLNLSAED
VRFILEKAGEIGENWRDHLGEFNYSSDDKPFYYFKGGDSLEFLNKKKEDLEPNITPRKSI
FSLTFWLTRILHKLIFIEGTPGCALMRGISSLAKKYHFFYRIFRRAEHLTKRVLFDCREC
DDCALFESYYLCPESQCPKGMRVGPCGGSRVKGHCEVFPERMCIWERVYWRAKNRRECHK
LNYIIPPRDWNLYETSSWMNYFLKYDHSAKKLEFFNHVYKVPEDMHIRCKR
>A0A7J0BK31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio subterraneus|TrEMBL
MLTSSRCFATQAPQSYEDRTLKIIDLIKARSTPFYSLEFFPPKERENWPAFFRTVERLKA
LNPLFASVTYGAGGSTQDNTLEITAHIKNVIGIEPMAHLTCVGADGAKIRDFLQRLRAEG
VNNILALRGDAPRTGDFSWDDQEFKYASDLVSFVRTCCPDFGIGAAGYPAAHPESQTFRD
DLAFTKVKVDAGSEFIVTQLFFDVREYFSFVEQLRAMGVNTPVLPGILPIQSLASVRRIL
TLCGANIPGKLYLALEEANDKGGDAAVKEAGLAFAVDQIRRLIDGGAPGIHLYTLNKAGM
CLEIADRVGLK
>A0A1A3BPP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium asiaticum|TrEMBL
MEVDCPKRMEFGPCGGVRPDGQCEMRAGACAFDDVVPWAGPAPARRPARWQNSGPLVLTD
FSCAPFDRGDVAATAAILAPACDAVLVGEHQNKPDFPPTLMGSLLLDVGVAPWITLSCRD
RNRVVLEQELRGLRSIGVDTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGVTPA
VPETPTAPPVHARPARLVEKQRAGADVAVLNHVPYPGMIANFMTAARSAGLSIPVIAAVA
VFTDSVSAAVLQGLPGLELDQAVTEQVLTATDPVAAGIAAAVAEARELLSIEGVAGVNVS
GLASASGAHIGAEIKAEVGRRIRQEAQ
>A0A3E3IKC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eisenbergiella massiliensis|TrEMBL
MIKELFSENKQLLSFEVFPPKKEEEFANAFLVLDSLAGLQPDFISVTYGAGGSKSKKTVE
IASYIQNNLKINALAHMTCVGSGKEDIDAVTAQLKEANVNHVLALRGDRPSYMSDEQFNS
RHFPHASDLTGYLNSSTDFHIAGACYPEKHYEAKDLDSVLLHLKKKCDAGAEFLITQLFF
DNQVYYEFLDKARSTGINLPICAGIMPITSAKQLGTTVSLSGSSVPKKLADLIATYGDDP
AEMRKAGIDYAIEQILDLKAHHVDGIHIYTMNKPKVAREIVSAIK
>K1YM55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MDAAQETSFPARQRFSLIAEMDPPKGVNLQGFLGTALQVRGRVDAVRVTDCEHAIMRMSP
VAPCLALKDKGFEPEMIITGRDRNRISFQADLLSAAALGIKKIIIKEGHDPAEGDQPVAR
TSGDLDLESMLQCAVALNSGRDLAGESLDGATDFHIGVGIELSDDINFNRERAEYFRKLA
AYGVQSVTLGPTYDVNIIEQFLPFAEETGIKLFTSVMFLKSVTMVRYLNNLPGVPSIPHE
FLKKMMQAPVKKDAGMQVAADLLRELAPLGEGIVLLAIGLKDKLPEFLDIIGR
>A0A091LF96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlamydotis macqueenii|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQSETFLK
FVKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>K1Z1P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MELKTKSKLEKVFKSGQLAVTSECGPPRSSDPEHIIKKGHIIKNHVDAINITDNQTSVTR
LCSLASCIHLKLEGMEPVLQMVVRDRNRIALQSDILGAASFGINNMLCLSGDHQSFGDHP
KAQNVFDLDSMQLIQTVRHMRDEGKFLGGEEIKVPPNLFVGAAANPFADPFKIRVPRLAK
KIAAGAEFIQTQCVYNLEKFELWMKGVVERGLHEKVFIMPGITPMRSVGMAKYMARAVPG
MDVPEELIKRLSGVPKEKQAAEGITIAVEAIQRLREVKGVAGFHIMAIEWEDKVPEIVER
AGLYPRPKFD
>A0A3E3I0B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eisenbergiella massiliensis|TrEMBL
MIKELFSENKQLLSFEVFPPKKEEEFANAFLVLDSLAGLQPDFISVTYGAGGSKSKKTVE
IASYIQNNLKINALAHMTCVGSGKEDIDAVTAQLKEANVNHVLALRGDRPSYMSDEQFNS
RHFPHASDLTGYLNSSTDFHIAGACYPEKHYEAKDLDRDLLHLKKKCDAGAEFLITQLFF
DNQVYYEFLDKARSTGISLPICAGIMPITSAKQLGTTVSLSGSSVPKKLADLIATYGDDP
AEMRKAGIDYAIEQILDLKAHHVDGIHIYTMNKPKVAREIVSAIK
>A0A4S0MRR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M3A.F.Ca.ET.201.01.1.1|TrEMBL
AEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVAGSAAA
>A0A6I3Q0E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLTKEKVADTLQELNEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQPNFEVN
>A0A7H0Y441|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus peoriae|TrEMBL
MKPDLRTVLNREIIVGDGAMGTFLYQLGFPVNTSFEELNITSPDVISDVHGQYLSAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
LELARNYEQQIDALLSEGVDGILCETFYSLDEIRIALHSVRKYSDIPVICQFAVDQVGRT
QDGFLVAEAFSVLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAKSFVDLGTRLLGGCCGTTPDHIAAISKALNRLQPPPLASKEALS
KESFQVAEQIADEEERGNGRHISEPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHALK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYVMTQPVYDHELIAAIAEATRHLEVPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGPEGRAMGVSIAKELLDTAMEHFNGIYFMTP
FMFYEMTAELTSYVWQKSGRAQAPLFRL
>A0A1F8LLU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium GWC2_73_18|TrEMBL
MDLPTSSARRAFHERLARAPILFDGAMGTLLYSRGIPQRACLDELVLSRPELIGAIHREY
LEAGAEAITTAAFGANRSRLAPYGIADQAARLNRRAAQLAREARDVAAREALVAGSIGPL
GAPLRGLEHRPEGEVRAAFREAIEGLLEGGVDLLLFETHNVLDELLAALDEARRLSDLPI
VAEMAFGQEIVAIDGTTPEAAAVALVAAGVDAIGVNCSTGPVACLDALARLGRPSGGVAL
SIMPNAGLPQRTEGRFVYAADPGYFGETVAMMLDAGALLIGGCCGTTPEHTAAMRTALDT
RLGARLGAGPRAPAPAEVTAAPAAIEAPRTAASEPGVVEPPPPTDLLRKLRDGRFVVSVE
IDPPRSIRLDRTLEAARLLRSAGVDLVNISDSAMARVRMGCLAVAFAVQRDVGLETLVHF
TTRDRNLMALESEVLGAHALGVRNVLCLTGDPPRVGDYPTGTGVWDVDSIGFIEILARLN
RGEDRAGSPIGQPAGFTIACALDPTADDLDGELERLARKLDAGAHLVMTQPIYHRAQLER
LLESVGRRWGSPRLPVPVLLGILPLHTARHAEFLHHEVPGITIPDEVRAAMHAAGERGAE
VGLEMAMALLAEVRGEVQGTYIMPSFGRYQLAAELVRRLRTADRAGAGTARGARTGADPG
R
>A0A7X2I538|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp. CAH-2|TrEMBL
MNVVNANPSSFPISFEFFPTKTPEGAAKHVQVRQDLYARKPEFCSVTYGAGGSTQAGTFS
MVRDIQAEGMQAASHFSCIGATSDKVRAELQQLQDMGVRRIVALRGDLPSGYGLGGEFHY
ASDLVAFIRREFGDWFHIEVAAYPETHPQARSPEADLKAFATKIQAGANSGITQYFYNAD
AYFRFVEGIQALGVSAPVVPGIMPITNSSQLMRFSDATGAEIPRWIRLRLQAYGDDVTSI
RAFGLDVVTRLCEQLRDQGAPGLHFYTMNQSAATLELCDRLGL
>A0A7Y3VKN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. A11|TrEMBL
MGYTHATHIDALNQSIAEVSDINVSFEFFPPSTPQMEETLWNSVHRLKELKPKFVSVTYG
ANSGERDRTHSIIKTIKDQTGLIAAPHLTCIDASREELITIADDYWHNGIESIVALRGDI
PPGGGKPEMYAADLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDIESYLRFRDRCVAAGIDAEIIPGILPVSNFKQAARFAAQNHVKVPQWMAKQFAG
LDDDPVTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPIAVA
>A0A2I1TUJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLTKEKVADTLQELNEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDIPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQPNFEVN
>A0A246U6T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. R72|TrEMBL
MALNSDARRKIGISFEFFPPKSEEMEGQLWNTVSELQDWNPDFVSVTYGAGGTTKAPTLA
TVSRFIAETPLATASHLTCVGATKDETHGVIETFRKVGVKHFVALRGDAPGGVGAPYQPH
PGGYANAAALVAGLREIGDFEISVSAYPEKHPESRDTAADIDMLKQKADNGATRALTQFF
FDNDNFERYLEKVRAAGVNIPIVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFDDK
PEERAKVAAEVAAEQIEDLARRGLTDFHLYTMNRAPLVSAVLTNLGFTREGAKKAGAAA
>A0A3M1LAI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium J083|TrEMBL
MTSRLRRAIQQREFLITAEVTPPKGGNPSRMVEVAHQLKNRVHSINITDGSRAVLRMSSL
AASAILLQEGIEPICQVACRDRNIIGLQADLMGAYALGVRNVLALTGDPVKAGDHKQAKA
VFELESVRLLQLISKLNSGLDFNDKSLPDKPLDLLAGAAVDPQLKSWSGLQSRFEKKLKA
GAQFFQSQMITDFDKLDKFMSKIAAGCDKPILAGIFLLKSAKNAQFINRYVPGVNIPEEI
INRLAKADDALQEGVKIAAEQVKLAKQLCQGIHLMAVKREDLIPEILDLAGIPPLKLE
>A0A1L7AGT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas gilardii|TrEMBL
MNHVATPGAGASGAGPGLEPGANPLGRWLTGPRFGALPAPAALPAPALSFEFFPPRTEAL
ENQLWACIRRLEPLAPRFVSVTYGAGGTTQARTHATVSRIVRETALTPAAHLTCVGASCG
EVDEVARQYWDAGVRHIVALRGDPPAGASDYAPHPQGYAYAADLVEGLRRIAPFEISVAA
YPETHPSASSAEADLDNLKRKIDAGATRAITQYFFDTETFLRFIDRALAAGISVPIVPGI
MPVSNFNQMRNFSARIGASVPDWMAALFEGLDDDIETRRMVAAVVAAEQVRLLQANGVDE
FHFYTLNRPDLTYAIAHILGVRPTRPAEPASESGVAEEGKAEAASRQVG
>A0A4Y9MVU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus sp. DF01_2|TrEMBL
MTPTVRELLAEARPTWSFEFFPPKSPEGATQLWTALRELERLHPSFVSVTYGAGGSTREG
TVSVTERIATETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNVLALRGDPPGADPQAE
WVAHPEGLQYASELVELIRSMGDFSVGVAAFPERHPRSPDFDTDVEMFVRKCRAGADFAI
TQMFFRAEDYLRMRDRVAARGCDVPVIAGVMPVTNVRQIARIVQLSGQAFPGHLAARFAE
LDGDRPEDRAAVRAYGVEVATELCRTLLDEGVPGIHFITMNRSTATREVHANLTAVGATR
>A0A1A7BCB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter dokdonensis DSW-74|TrEMBL
MTPTLDQLHEYRTATDTPLFSGLPGDVAVSFEFFPPKSEKMETQLWDAVTQLRPLGPSFV
SVTYGAGGSTRERTHATVARIISEGKLPAAAHLTCVAASKADIREVAEQYWEAGVRHIVA
LRGDAGEPGAPFTPHPEGYASAAELVAGLRDIADFEISVAAYPETHPDAASPQSDIDNLK
RKLDAGATRAISQFFFSADTFFRFRDACAAAGIDAPILPGILPVTNVAQARKFASACGAA
IPAWMDGLFEGLDAMPAARQLVAATVAAELCRRLYAGGVRDFHFYTLNRPELAYAICHLL
GKRPTGEAA
>A0A1X0YA43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geothermobacter hydrogeniphilus|TrEMBL
MGDLAIELVPRSREVLERDLQTVREHFPRVRTINIPDLLQFPLRAWDAAEAIAPQVERVI
PHLRAIDFDLQEDWPFLDTIRRSGCPAVLAISGDPPQDMLHRTFRTPVTEFISRLKQELP
GVKIYAGLDPYRSGVKEELDYVRAKLNAGADGLFTQPFFDLRFMEIWADLLIGLDIWWGI
APVLTEKSQAYWENKNNGFFPPDFEPTLEWNRQFTRRALHFVKTRGASAYIMPIRADIRK
YLDGII
>A0A2N4XYE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. TH135|TrEMBL
MTKTERPIAKPSDLKVSFEFFPPKSPDMAEQLWQTVEALQPYQPDFVSVTYGAGGTTREP
TLATVKRLIADTPLATASHLTCVGASREEVRAVVEEFQAAGVRHFVALRGDPQGGVGTRY
APHPGGFVNAADLVAGLRDMGDFEISVSAYPERHPESESEAVDLDMLKQKVDAGATRALT
QFFFDNDVYERYMDRVRAAGISIPIVPGIMPIQNLTQLKRFASMCGASVPAFIDARFEGT
ENDPQARAAIAADIAAEQIADLSRRGVEEFHIYTMNRAPLTIATLERLGVSAKAQTLSGA
AA
>A0A352XR12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ktedonobacter sp|TrEMBL
MEHTFLEQLRKRPLLCDGAMGSLLYARGITYEQCFDELNLIQPELIESIHSEYISAGAQI
IETNTFGANHAKLETYNLEERVREINIRAVKLAREAREISGQPVFIAGAVGPSGRPLQAP
DEQRLSELRTIFREQIDALLVGGVDLLMLETFSSLAELRQAVLAAQDVGGLPIVAQMSFY
EDGHTLSGQSAARVAAVLNDMGVDVMGANCSVGPAATLDVLQEMIAADEQFGDNKRAVPQ
MFSAQPNAGLPTRIGNRFFYMATPDYFADYTVRFARAGVQLIGGCCGTTPRHIGAMRKAL
DGVYGAATSFIPNTSRESQQAKPIEITNGKATIAGLIEEEVILPQQGTKTRLQEKLEARE
FVVSVELDPPKGLNPAKILEGAALLQKVGVDFFNIADSPMARVRMGCIAMARLIQDHLGI
ETIIHFTTRDRNLMALQSELLGAHALGIRNILSLTGDPLRVGDYPNTTGVWDVDSIGLIR
VLRGMNEGHDAAGSSIGAQASFHIGAALNLNMTDEETDQEIEKYRRKIEAGAHFIMTQPI
YELAPLERFLERAGKPPIPILLGCIPLHSSRHAEYLHNEVPGITIPDDVRSRMRAAGEQG
HEEGLKLAQELLMSARSMIQGVYLMPSYGRYDVVSKLTKMLLMQQIV
>A0A2E7ZQH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MWSKSQLQALLDQRIVVFDGAMGTQLYEQGFSFQQSLDALCVENPLVVRRVHRDYVGAGA
RILTANSFGANRMRLDHKGSSAKIIEINQAAVAIARDAAMDRPPHNRPLVAASVGPLGQP
MAPVGRISEAKAREVFTEQIEALLDADPDLFIFETFSDLNELLVAIDALNSLYEEAAFVA
LATFNAEGKTLLGHKPEEVVRAVLAAGAAAAGGNCGVGPQGMEEVFERMCRVAEARLVFT
PNAGLPQVIDGRLHYVNSPEYFAQWAEELVQRGARGIGGCCGTTPEHIARAVQAIGSRSP
VPLQAAYGESVSSVVESGGTSSEVQSIETDSSSWSDSDFENKLSTGQFVVSVELDPPRGV
NAERLVRGAVACRQAGVDAINIADSPMATARMSPLALAVLIRQQVDIEILLHVSCRDRNV
LGLLSETMGAHALGVRHMLCVTGDPPSVGDYPGTRAVFEVDSIGLLTMLNGLNHGRNANG
KPRKYNTDFRLSCAVNPTAEDLDREIEKFHAKQDAGAKYALTQPIYDIDIFEQFLERAKP
KIPLLVGILPLRNARHAHFIHHEVPGMYVPETIRKRMDEAGESGPSEGVVIGREFLERVR
PLCAGAYLMPPFNKFEMAIELLKD
>A0A0N1J4Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptomonas pyrrhocoris|TrEMBL
MAEYISTILAEEDPNKWYTSFEFYPPRCERTEEELMNVHIPAFAKQSPVFLDLTWGAGGR
TSNTTLRLSKQLQDTYPNIPVNMHITCTNMPAGLIKESLEFAKQSGIRNILALRGDAPQG
EEFKANPDGFACAKDLVKHIRRTYDDFFCVTVAGYPEGHPSKIADDGTITEEDYQQELDY
LKAKVDAGASIIVTQLFYDPSIYVAFVHRCREMGINVPILAGLLPITTYAGFKRIVKLCK
THIPDDVRQKVESLKDDHDGLKAYGVEQCLAMIHYIRNAGLEYNHLHFYTLNNTSQTFKV
MRRLGIHVE
>A0A510TWZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schleiferilactobacillus harbinensis|TrEMBL
MQINQLFKDRPVISFEVFPPRKNATAASLRKMDETLAVLSDLHPDYVSVTFGANGALQAT
GTLATASYIKDTYGIETVAHLPASQLSADQIHGLLNELQAHGIENILALRGDIPAGGRLS
NDFPHACDLIRYIHQCGDFNVIGACYPEGHPESPDLATDIHYLKDKVDAGASHLISQLFF
DNQVFYDFVAQARAAGITVPIQAGIMPVINAHQIERMATMSGVALPEKFTRMMARFQDNP
VAMREAGIAYAVDQIIDLLVHGVDGVHLYTMDNADVAQRIFAAAEQVIHA
>T5BQ69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomyces dermatitidis ATCC 26199|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDTALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDDQDDPELLMEHLKEKVDAGGTF
IITQMFYDVNNFLTWVEKCRQKGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEAL
EPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQATKMILDELGLIPSHKTP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSLKELSEIFIRFLNGSLDRLPWSEGAVTEETEIIKSDLLD
LNRKGFLTINSQPAIDGMPSSHPIYGWGPKNGYVYQKAYLELLMSPTMIDDVISRIEQNS
DLTYYCVNKKGELKTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHAPSSLSRRLIEQVMDTWYLVNIVNNDFHKTHDIFNLFKDLKVENLDTEIEPIALAAE
SVDIAQQNGQLPQTEVNDSCTEATKSMEERNSN
>A0A126Q5G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas macleodii|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGA
>A0A0B7JHX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium kishitanii|TrEMBL
MVNQDLVTNTESELRVRYNDITRGVYFIGTTPPKTNTPLDEVETIADRLVNRIKDLAIDG
LIVYDIQDEVSRTKKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSETDAFDEWL
NEAWHEYQVRDIVLVGSPSAKNEVSLPLSAAYQALAENKNNFFTGGIMIAERHAKKGNEH
ERLIEKYQQGCNFFISQAIYDTQATIDILTRYAIECKQDGIKPQRILLTFSPCGSAKTLE
FIEWLGVSVPEATSLRILNATNPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRK
EEIDGSILLYKLLRASMDSHLAKHEFRMLQKNTVTVL
>A0A418L2W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus|TrEMBL
MTTNPLDRDGPVAELQDPGSIADRLTAVQPGEIAFSVEFMPPRDEAAEARLWRAARVFER
YRPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWVPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPTALEERLLRAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTARG
>A0A7F5R8V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrilus planipennis|TrEMBL
MIHLKDKIDAKADFIITQAIFDNKTFQTFQNRCRSFGIEVPIVPGIFAFTSQKSLLKMSQ
FCDIMVPQEVSAIVEQNKHNAMSVYNFGIHFTTELIKNLLTAKKDPIIDVHLFTLNNIYA
VYEICERLGFCTLNIERPLKYVE
>V4J0V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp. PB-SRB1|TrEMBL
MVGEAQRSGSQAATLIAEVDPPKGVNLTGFLDKTLLMRGRVDTIRVTDNEHAIMRMAPIA
PCLALQEKGVAPSMMIAGRDRNRLSFQADLLSAAALGITDIVIKEGHDTREGDQPVARSS
GDLDLPTMLACVAALNSGTDLAGETLDGATSFTLGVYLELSDDVNLNRERAEYFFRLREF
GVSSVTLGPTYDLNIIEQFVSFAEQTDIKLHTSLMYLKSVTMIRYLNNLAGVPSIPQEFL
RNMMSVPDKKNAGIAVAADFFRELAAISDGVVLLSLGWKDKLSEFLDRIER
>A0A7R9R588|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MNFRKKIETRKFVVTTEVTPPRGTDTTTLREELDLIPRSVDAVNLPDNQRSIMRMSPIGA
VHLLHEKGCEVILHITCRDRNRLALQSDLLGAWSIGVKNILAMTGDHPLIGDTVGAKPVY
DLDSTQLLQLIQNLNRGRDIMNRQLEGGTDFIAGAVVRPDPDDKMQLLKLEKKVSCGARF
IQTQPVYKTEEFKKFLKKASHLKTHIIAGILPIFSLKTVKFIDEKLPGTTIPEEVKQRIK
NSTDPANEGIEIAAEIIRELQSVAGGVHIMPITTHRYTEAILRRADLL
>A0A172T3R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium pennivorans|TrEMBL
MDETNKTEFFAYRFILETLPPRGTNPDKYLAFCKEAVEQGAQIIAVTDLPMGSARVSPIA
PAHMLVEMGLEVLMHFSRTTRNAIRIEGDLIAAHMLGIKNLLILSGDDPRVGTYPFSSSI
EDFSIYDVFKLTKLLNEKGEDLAGLKIFGSFSFNAGGVFSPFEKDLNQTLERMELKMQNG
CQFFVSQPIFNSETILKLFEKSEAEELFRRTKIYIALMVFESFQQLEHYSKVPGVFVPKE
YFRQKNDAHLEQYSIHQCISIIEKLAPYVHGFYLTSTTKKMETIKTISDAVVSQY
>A0A1C6JTK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Blautia sp|TrEMBL
MKLSEAMRERMLLSFELFPPKTEKGMDNLPGTIDHLMKYKPAYISCTYGAGGGNVGANRE
VCQMIKKAGTTPVTHFTVIKNTKEGIKEQLDQYLAEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDSIREAGVTMPVDVGVMPILDMSATINMALSRNGCVMDRELCRLISRNWLFPN
PFAAKDADGKPFDMFYDDKIKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLCTLI
>A0A2V9PFY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPGDLLARLKTSAVLCDGAMGTWLYSKGIFINRCYDELNLSQPDLIRSVHHEYLQAGAEI
IETNTFGGNSYRLDRHGLGGKVREINFAGARLAKEAAKSFDAWVAGSVGPLGIRIEPLGK
TSFQEAKDAFREQIAALLEGGVDLLILETFGYVEELHQALLAARELNPKVPVIAQVTVDE
EANCLDGSTPETFAPRLEQWGADVMGCNCSVGPVAMLDAIERVRAATSLPVSAQPNAGIP
RSVEGRNIYLCSPEYMASYTRKFVAAGVKLVGGCCGTTPEHIRVMKSALRASQARTRASD
PQINAKTAVPRAIATVPLSERSRLGAKIAQGQFVSMVEIVPPKGTNIQKELEGARFLKSV
GVDGINIPDSPRASARMSNQALSVLLQQQAGIEAILHYTCRDRNVLCIQSDLLGAAAVGI
RNLICITGDPPKMGGYPDATAVFDVDAIGLVNIVHNLNRGLDIGGNPIGNGTGFAIGVGA
NPGVSNIDEEIHRFEYKVQAGAEFAVTQPVFDLSLLENFLRRIEHCRIPVIAGIWPLVSV
RNAEFMKDELRVSVPDSILERMTRAPSPEAAREEGISIAREMLTAVRGMVQGAQISAPLG
KYSSAVDVLEALGSTGAGAS
>A0A4S9B451|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEIAAPEAPQ
KVNGATNGEKHEEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A2N8J260|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia muciniphila|TrEMBL
MKLSELFPQKRVLSFEVFPPKRTSPIGTVYHALSALQGLNPDFISVTYGASGGAGTSDTL
NIASSIKKDYMVESVAHLPCISLTKGNVLELLEQFRRNGIENILALRGDLPPDREPCRDF
TYASDLISFIKEQGNFHILAACYPEGHPESKSIVDDIRHLKTKVEAGADHLISQLFFGND
IFHAYREKLDLAGISVPLEAGIMPVVNKKQIERMVSLCHVHLPKKFIRMMERFEHNPIAM
RDAGIAYAVEQIIDLVAQGVDGIHLYTMNNPYVAGRICEATASIIRN
>A0A6A9GRP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPKKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>B4V6E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Mg1|TrEMBL
MSGLRELLASGQRSFSFEFFPPKTDAGERVLWNAIRRIEAMAPSFVSVTYGAGGSSRDRT
VEVTKRMVAETTLLPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGNPNATWT
AHPQGLRHADELVSLVRASGDFSVGVAAFPEMHPRSPDWDTDIRHFVAKCRAGADYAITQ
MFFHVEDYLRLRDRVAAAGCDTPIIPEIMPATDARQIGRFAELSGAAFPEELAGRLEAAK
DNPADGHRIGVEYATAMADRLLAEGAPGLHYITLNRSTATLEIHQNIIESRSAHALAHG
>A0A0V1J403|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella pseudospiralis|TrEMBL
MAIILQSALLVCISVYCLMIFFYSNNYVVFFPILCYPTGHPDASSYEEDLLNLKAKVDAG
ADFIITQLFFDEMHYFKFVNDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSKIVIPDSVL
TTLESIKENAEAVRNFGISFAVELCRKSILEQIGLWKESPVRMLPWKKHPVHSVRCREAV
RPIYWNTRPKSYLCRTRDWKQFPHGRWGDLGNPAFGDLKHYLFSCIDQMNDSCALDMWDK
ELSSFEHVRDIFCNFIARTPNRHGHTVRRLPWNENHSDPAVDVLKDELIYYNSNGILTIN
CQVAVNGLPSNDPIFGWGEANGYIYQKGYLEFFASSKCTTILLNHVQNFPSINYHAINFD
GSFETLNYDEDATMALTWGVFVGQEILQPIVANAASFRVWKDEAFDLWQRWARLYESGSI
GRKLLQSIHDDHRLITLIDNDYPQPCSLSALLRAVIDECCEEKKIDDE
>A0A4S8VJP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSLANS
APQNRVVVDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVE
FFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLL
EA
>A0A4S9UAJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRSGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDHDTPVANGNGDKKAKARRRSSIANS
APQNRVVIDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVE
FFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLL
EA
>A0A2I1TL72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHEATHSLFKHHSQVSAL
>A0A2N8PRV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus avium|TrEMBL
MSSTLSFEVFPPNTQVGTEKLLTTLEELQQLAPDFISVTCSNNRQTIEETTLKVADYIHT
ELQVPTIAHLPAAYLDQAQVQRLVTRLDQIGIHQILALRGDIIPELPPKQDFTYASDLID
YVKQQAPHFHISGACYPETHPESQNRIEDVKNLRRKVAGGCDQLITQLFFDNELFYQFQE
SCDLADIKVPILAGIMPIVNRKQALRLIKTTNTKLPRKFLAILEKYEHDPIALKEAGLAY
AIDQIIDLATQDVAGIHLYTMNNAEVAKHIYYNTKNVLKGQIEVR
>A0A480RAG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKH
IRSEFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLK
ACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GQELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIV
DVKVGASLGHRVRGRHIYATIRQSRSAPPIQALCQTDTQTEPGPCPLRAPSLAREAIRG
>A0A4X1W853|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRGPWLGQGDLVHGDRQHGRELLRPGDHTAHDLLPSEPGGGHGY
LHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKGH
PDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACSEMGITCPILPGIFPIQG
YHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFY
TLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQELTSEESVFEVFAHYLSG
EPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGWG
PSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMLIQYIHDNYFLVNL
VDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>A0A480XWN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKH
IRSEFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLK
ACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GQELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMLIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNKPPHNEKEPEANDPAP
>A0A7C8PB19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orbilia oligospora|TrEMBL
MHIKDKIAACEKAGKPCFSFEYYVPKTAQGVQNLYDRMERMGSFGPQFIDITWNAGGRLS
NLTTEMVNVAQTVYGLETCMHLTCTGMEKEKVDNALQEAYNGGCTNILALRGDPPRENEK
WSAVPGGFRYAKDLVKHIREKYGDYFDIGVAGYPEGCDDEVDPDILLDHLKEKIDAGGTF
IITQMFYDVDIFLDWVNKVRAKGITVPIIPGIMPIHTYAAFIRRATWTKIHVPEKWLEVL
EPVKNDDVAVRDIGRDLVVELCKKILAAGINQLHLYGTTRST
>A0A7R9UMU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diacronema lutheri|TrEMBL
MSRMVGGRRDTGGGAYESPSAVLLDALVDPSRPVFLFGTVPPREGTSFESAADICEKFVA
RSRALATDGFLVYDIQDEAGRTKEPRPFPFTKTLDAAEYGALLQRRSGKGAVVYKCVVEA
SHESFDCWLDDAISRHDHRCFNLVGGASSSVNYSGPTMPDAAEKVLARSAAFGCVTIAER
HAKKGTEHTSLLRKSEMGAKWFISQAIYDTEATVKLLHEYGSLCRYKNVPPTKVILTFAP
IGREKTLKFIRWLGVNVPAAVEERILGAGDEERKARSKEENVAQCVQILCECLRTILMQT
SSAGVPLGVSVESVSIFKEEIDAAHVLFAKLQAIMLDAHGCPWKVKWAYTLPPTAGERAV
AVMHAAATQAGVTTAAAAAANAQAAAVVGRSGIALDLTENQIVQVLLALAVGFLIGAHRS
S
>A0A4Y8AF10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter phyllosphaerae|TrEMBL
MKITEHIANAAGKTLFSFELIPPLKGQSIQGIYDAIDPLMEFKPPFIDVTSLREDYIYKE
HQTGLLEKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLQFLGIDN
VLVLRGDARRGDASFVPTPNGHCYATDLLQQVVNMNNGVYLHEHYEGILKTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGAGFIVTQMFFDNQKYFDFVNNCRAVGINVPIIPGLK
PITTSKQLVNLSKTFHIDIPEALSDAIHDCKDEKNVKDIGIEWMIEQCKELMKFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A6T7JAY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Attheya septentrionalis|TrEMBL
MNLKKMAYRTIEFSRKVAFNGMRKEATHYILPDLPSAITPQLRELFYKTVPTNQRIITIA
ACRHTPSTLKKEIDQLDTNRILLVGGNEKQDASLSSEHALTIIREHSNLIPWCVWDPNSV
DSQNRLLDKQQAGAMGVVTQPLFTTRAWNNIQTVDINIECIAGIPLISSRKNFMFWLDLL
EGDTESFISDPVLCHSLDYFHEPMTQQNAPLLYANSYLEQLLSLEVVQGVHFMPMNNTKV
LNNILTDNF
>A0A0S7DMC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus lentulus|TrEMBL
MHVKDMLADNESAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEA
WEATEGGLRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
VVTQMFYDTDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEAL
EPVKNDDAAVKEIGKRLIADMCRRLLAAGVKHLHFYTMNLAQATQAVLEELKLIPSEETP
LQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSIRDVTQIFVRYLEGKLDRLPWSDSPISGEANAIKNNLVQ
LNSRGLLTVNSQPAVNGVRSSHPVYGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNP
DMTYHAVAKNRELRTNTRDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQDIMDNWYLVNIVNNDFHNTYDLFDLFNGLEVKDLDIEVSSDTVEIK
SQPNGAAPEELAVKN
>A0A1H1EQE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas grimontii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQMISNMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A533WNI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MTITYELNPPKVIQDTVLSHEELQNSVNKLKAKAFEVSNVCNSIHVTDSVLGIPRISPIT
IGVFIRNSNDKIELSASVRVRDRNLTSLTQTICDAILLDLNAVLILKGDPPPAGPKDSKL
VPSEVVKQFNEQGFGKKIDLFLSLPSNPNFEKIHKKIEAQPKGFVTQVISSQDQITKIVD
KLKPQGFKIIPCILLPSEKNLQSAKRLNFDWSNYSNDVVGFIKEAHKISGNVLISSPNDF
KRALEVLKKLT
>A0A2S3SCH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio vulnificus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSTPQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAQTGLVAAPHLTCIDASREELINIANDYWANGIKNIVALRGD
IPPGGGAPDMYASDLVTLLKSLHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLEDDPVTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKKA
>A0A351RRL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium|TrEMBL
MGLREIFVQKDFVVTTEIPPPKGVNTASSLDIAKKILGRVDGINVTDNQRGIMRMCSLAF
SHLLKEIGHNPIMQACTRDRNRLALQSDILGAGALGIENICVMTGDHPKLGDHPDAKPVF
DLDSIQLIKVIKEMETGVCMSGKRLESSAKFFVGGVANPFFEPFELELIKIKKKIDAGAE
FFQTQPFFDKESLEKFLEEVRGLNTKFLIGISPIKSIKMINFLNEKVLTKKIPENISKRV
ETAENQTEEGIRIAAEFIREIKGMVRSIHIMPIGIESYLPYLLNEAEL
>A0A7C4D721|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MPEAFISELMRSLKSGKFTFTGELEPEKTTNLARYVEAAKKIKDYVVACNVTDNPQSFAY
ISSLVASYIIQRDSGLETIYQITCRDRNRIAIFSDLLGAGALGIKNVLALTGDHTTLGDT
PQAKPVFDLDSVQLIKMIRRMVSEGIDMNGKPIESPPKFFIGAGANPNANPIEPELIKFE
KKVNAGADFFQTQVVFDIEKAKSFLKEVSKYNVPVIIGIFPLKSYGVADYFDKNVPGVKV
PKELMEALAKASEISDKNLRRLKYDEINLNYFTNFIRELRKTTSAAGCHIMSVGYEEIIP
PLVEASR
>A0A7K3IU08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSVIEKIKNAKGPLFTFELLPPLKGHSIERVYSAIDRLVEFDPAYINFTSHRDEIIYSER
PDGLLEKKIVRKRPGTIALAAAVKYKYNLTVVPHLLCGGFSREETENVLIEMNFLGIDDV
LALRGDPQKGSRTFIPEKDGHSHTSDLVKQIINMNNGKYLEELLEDTTPTSFCVGVAGYP
EKHNEAPNRHVDLENLKLKVDSGASYIVTQMFFDNSKFFRFRDECKAIGINVPVIPGIKP
ISALNDIRMLPQTFHIDVPNDLVNAIKKCTTDKDAREVGIEWAIMQSKELISKGVPGIHY
YTLGRSDNVARIVRASF
>A0A395UXC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] rectale|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNRYNVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>A0A7J6DT47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cannabis sativa|TrEMBL
MKVIDKIQERSNDKVLFSFEFFPPKTEEGVDNLFERMERMVAHGPSFCDITWGAGGSTAD
LTLDIANRMQNTVCVESMMHLTCTNMPVDKIDHALSTIKSNGLQNVLALRGDPPHGQDKF
VQIQGGFACALDLVEHIRAKYGDYFGVAVAGYPEAHPDAIGPDGVASLEAYQNDLAYLKR
KIDAGADLIVTQLFYDTDIFLKFVNDCRQMGITCPIVPGIMPINNYKGFIRMTGFCKTRI
PSEVTAALEPIKDNDEAVRAYGIHLGTEMCKKILASGIKTLHLYTLNMEKSALAILMNLG
LIEERKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTSGWEQYPQGRWGDSRNPS
YGALTDYQFMRPRSRDKKLAEEWNIPLKSVEDIHEQFKKLCLGKLKSSPWSELDGLQPET
KIINEQLVKINGKGFLTVNSQPAINAEKSDSPIVGWGGPGGYVYQKAYLEFFCSKDLLNA
LVEKCSRGFPSLTYMAVNKQGHWLSNVDGTCVNAVTWGVFPGKEIIQPTVVDPTSFVVWK
DEAFEIWSRGWARLYSDEADPSRKILEEVENSYFLVSLVDNDYIHGDLFAVFNEL
>A0A8G0GTY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Riemerella anatipestifer|TrEMBL
MKVTEHIKKSEGKTLFSFEILPPLKGQNIQCIFDAIDPLIEFNPSFIDVTYHREEYEYVE
VRDGLLEKRVVRKRPGTVGICAAIQNKYKVDAIPHILCGGFNREDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKNGHTYASDLVKQIQDMNKGIYLDTSLEKAAPTNFSVGVAGY
PEKHMEAASFSQDIGHLKKKVEAGADYIVTQMFFDNQKYFDFVDRCRSEGIGVPIIPGLK
PIATKSQLSLIPHRFKVDLPDDLVTAITKANNNNEAKEIGVEWCIEQSKDLMKNGVPILH
YYSMGKSESVRKIAEAIF
>A0A1A9FKJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella pseudogrignonensis|TrEMBL
MGFYGLSRRPDIGQTTRVSFEFFPPKSEEMEQRLWETVTRLAPLKPEFVSVTYGAGGSTR
ERTIRTVARILKETDVQPAAHLTCVDATSEEVDRVAQEFAALGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVGGLRKLADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPYAICHMIGIRPKTEAQL
EVA
>J3NNB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gaeumannomyces tritici (strain R3-111a-1)|TrEMBL
MHIREMLAEADRTGKPSFSFEYFPPKTAQGVQNLYDRMERMYHLGPKFIDITWGAGGRIA
ELTCEMVTQAQTYFGLETCMHLTCTDMGVEKVNDALAKAYKAGCTNILALRGDPPRDKEK
WEAAQDGFQYARDLVAHIRKTYGDHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDMGASF
IVTQMFYDVENFLRWVGRVRERGITIPIIPGIMPIATYASFLRRANHMQARVPEEWIRRL
EPVKNDDAAVRIMGKELVVEMCRKILAGGINHLHFYTMNLAQSTTMILEELSWLPSPTQP
LKQALPWKQSLGLGRRGEDVRPIFWRNRNKSYVMRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLVGTNEQNRQKFGEPRSFKDVASLFIRYVEKEITTLPWSEAPLTSEGELIKDDLLD
LNRRGLITINSQPAVNGVKSTHPVHGWGPPNGYVYQKAYLELLVHPSLFADMKSRLHTHP
DLTYYAVTKSGTLETNATYEGPNAVTWGVFPGKEIVQPTVVEGISFLAWKDEAFQLGMEW
GRCHEANSPSRVLIQKMMEEWYLVNIVNNDFHSPRTIFDLLKDIKVPDLEKEVAIPTDQG
PETNGINGTSVITNGSHPAAPTATAAVAV
>A0A0P9MDN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cannabina|TrEMBL
MEASSPMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLN
TVLQLENEVKVPAAPHLSCVGDSKDDLRSLLAQYKAAGIKRIVALRGDLPSGMGMASGEL
RHANDLVNFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFN
ADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQ
SIQAFGEEVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLQLPR
>A0A0A3EQ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio campbellii|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDATRDELIDIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A849NVI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter indicus|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDKDIQHFVEKVNAGANAALTQFFFNPDAYFYFV
ERIQQAGVNIPVAPGIMPITNASNLIRFADSTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVLKFCERLIAGGAPSLHFYTMNNTEPTRQLVTDLGLA
>A0A5F1YPV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira wolffii|TrEMBL
MKKILEIYKEARGPVYSFEFFPPKTEEGEEKLFEAVGELSKVDPGFITVTYGAGGSTRDK
TIRLTSELAKKYSLPAAAHFTCVGGNRDEIRTILAQIYDSGIRNLMALRGDPPKGEGQFR
KVEGGFGHANELISFIREEGFDFCMGGACYPEKHPEASSLEEDVDRLKDKVEAGASYLVS
QLFFLNSSFGAFLDLVHKKGIHVPVIPGIMPITSFSQIERFKSMAACEFPPRLISDLEAV
KDNPSEFYKRSVDFSVAQCRELVETYRVPGVHFYTLNQSPASSDIVRRLKSS
>A0A804JYV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Musa acuminata subsp. malaccensis|TrEMBL
MKVIDKIRAATEGDGRTVFSFEFFPPKTEEGVENLFERMDRMVAHNPTFCDITWGAGGST
ADLTLDIANRMQNMICVETMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQD
KFVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDMIQGDGGATLEAYNSDLAYL
KRKVDAGADLIITQLFYDTDNFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKT
KIPSEITAALEPIKDNEEAVRAYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
FGLIEESKVSRSLPWRRPANIFRVKEDVRPIFWANRPKSYISRTVGWDQYPHGRWGDSNN
PSYGALTDYQFMRPRSRDKKFQEEWATPLKSAADINERFMKFCLGKLRSSPWSELDGLQP
ETKIIDEQLSQVNLKGFLTINSQPAVNGEKSDSSAVGWGGPGGYVYQKAYLEFFCSKDKL
NLIIEKCKTLPSLTYIAVNKEGDSVSNVAPNAVNAVTWGIFPGKEIIQPTVVDPASFMIW
KDEAFEIWSRGWARLFPEGDPSRELLEQAQRSYYLVSLVDNDYIHGDIFAAFKDI
>A0A379TI57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. arizonae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>G8YA65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL Y-12695)|TrEMBL
MSTVKDKILSLKENERFVSFEFFPPKTDTGFCNLLARLNRMSALNPLFITVTWGAGGSTS
EKSLDLATTCQKDVGVTTILHLTCTNTNKSVIDQALKKAKENGIKNVLALRGDPPRTEEY
WTPDCDFSNAEDLVKYIRETHGDYFCIGVAGYPEGHVDGADTRNQSPEKDIPYLIRKVQA
GADFIITQLFYDASKFLKYEALLRSHDELKDIILIPGLMPVTTYSVFKRATKLSHASVPD
DIAQKLQESSVDDDLVKELGVDIVTKIIKEINAKTNNRIKGYHFYCLNLEKSVASIMNRS
DVLRPIMEAPSNLNENENAIESDTEEPDELAKGKGRHEKRRRKSSLLNENAVADKSLVQK
TLIGKSLLGDKKTLVDISSGKGSLGKDANWDEYPNGRFGDSNSPAYGEIDGYGPSLKVSS
ASEAIAKWGSPEKESDLTNVFIKYLSGEIDSLPWVDAALSPETALIQEELFEINKKGYFS
LASQPAVDGVPSCDKIFGWGPRNGFVYQKAFIEIFVPKKKWDDVILVNLKKYFDNMSITY
YCGDNKGNVTSNLPLSKDSHNIKNTITWGVFPQKEVLSPTIIDFESFKAWNEEAFILWLE
WARCYKRDSKPYQMLNSVYENYYLVSLISHDFKDEHALWNALLQNN
>A0A2H0ZNC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida auris|TrEMBL
MSTVTSKIRSLAPGERFCSFEFFPPKTDAGFRNLLARLSRMMALNPLFLTVTWGAGGSTA
EKSLDLAATCQKELGVTTVLHLTCTNTNKEIIEDALQRARAAGIKNILALRGDPPRTEEY
WTPNCDFSSAVDLVRYIRQNHGDYFCIGVAGYPEGHVEGADASQQDPRKDLPYLVEKIEA
GADYVVTQLFFDVDKFVAYEKLLRETPQLKNVILIPGLMPITTYRVFVRATRLSHANVPR
DILSKLDAFANDDDTVKTIGLDVLTKMISEIDQRTEGRIRGYHFYTLNLEKAVASIINRS
PVLQNMISHNKSVEHDDAVASDSDEEFAPPMKNGRRKSSVNENQVAVPDDAKRALVSKAL
SKDPKSIVDISTGKGALGKDATWDEFTNGRFGDSNSPAYGEIDGYGPNLKLHTNKEVEET
WGNPESTADITRIFVDYLSNKINVLPWADSELSPETGLIQEELFELNERGWFTLASQPAV
NNCKSSDKILGWGPPNGHIFQKSFVEFFIPKKQWKDELLPRISKQVEEKTITYYCGDASG
HISSNLPIGKGKDSNTKSAVTWGVFPSKEVLQPTIIDYESFKAWNEEAFLLWLEWARCYR
KDSKSYQLLNDIYNNYYLVSLVHHDFTDEFVLWTTLLSD
>A0A0K8TVL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bactrocera latifrons|TrEMBL
MALKTPPNCERSKAFYATLKSSAISLHGSERIQLFEKLFINQIAIACGYGRTTKVPLTQY
QNKISVLKQNLRTSDIRIQKTMHNPDYVPATNSCNATTSICGGHVPLPTAPRPEFHPVFV
RFSSKQQPPEQRKLAELFKQKVAAKEFFYGIELTARSYGKQPSLLDYNGFDVLLPLFTSL
VWLGRDYANVEDVNAIEAISLGRLLQQHVVVLPHFTCYRADSRRLDDFLTLNFTNVLVLR
GDDVVPQQQFQHAKDMVEYIHSKRGDTISIGVGGYPEGHPESKSMEEDMKYLKEKVDAGA
DFIVTQICFTPESIISFVQKCREIGITVPIIVGVIVPDNMRILHFIMNIVKAVIPEEQLS
KYKELEEDRKAFKAYAVENAVRTVQILLDSNLDVYGFQFFTMNRLKSVQQVIQQILNMNQ
TQST
>A0A0G3CU67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pragia fontium|TrEMBL
MSFFHANQREALNQSLAEVSGQINVSFEFFPPSTTEMEQTLWQSIDRLKTLKPKFVSVTY
GANSGERDRTHSIIKGIKDKTGLDAAPHLTCIDASSDQLLDIAKDYWNSGIRHIVALRGD
LPAGGGKPDMYASDLVALLKSVGDFDISVAAYPEVHPEAKSAQADLINLKKKVDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLERFAKMTNVRVPQWMTQMFS
GLEDDIETRKLVGASIAMDMVKILCREGVKDFHFYTLNRAELSYAICHTLGVRPA
>A0A0T8BNK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A0P0EZQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides thetaiotaomicron|TrEMBL
MRVIDLIHNSEKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLFWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEALKCKNDKEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A3R9CVS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter haemolyticus|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDADIKRFIEKVQAGANAGITQFFFNPDAYFYFI
ERLEKAGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLSAYGDDSASIKAFGHE
VILKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1V2DQZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter lutaoensis|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRDRLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHRQGISTAPHLSCVGGTRQDIAELLDLYREHGITRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEDDLKNFARKVKAGANSAITQYFYNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSESIRK
FGEEVVTDMCERLLKAGAPGLHFYTLNQAEPSLTIWNNLGISDREKIAF
>A0A6I3AAD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARIADLLARGRTFSFEFFPPKTDYAQLTLGRTIAELESLSPGFVSVTYGAGGSTRARTH
AVVEWVRKETHITPMAHLTCTAHTRADISEILANYTDAGVENILALGGDPPAAGADPGPS
DYSYALDLVEHIASADGFSIGVAAHPEMHPRSADRASDRRHLAEKLKRADFAITQFFFEA
DHYFRMVDELASLGVDKPIIPGIMPVTNKNQVKRMAELSGSVFPAWLAERIGDSGDEAEV
ARIGVEVATELCATLLDGGAPGLHFFTMNRSNATREIYGRLGLPTS
>A0A8I6A5Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rattus norvegicus|TrEMBL
MSNEARRSGSPSPRSEGSSSGSESSKDSSRCSTPSLDPDRHERLREKMRRRMDSGDKWFS
LEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNYCG
LETILHMTCCQQRQEEISGHLHRAKQLGLKNIMALRGDPVGDHWEAEEGGFSYATDLVKH
IRNEFGDYFDICVAGYPKGHPDAESFEDDLKHLKEKVSAGADFIITQLFFEASSFFSFVK
ACEDIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQTIKDVIEPIKDNDAAIRNYGIEL
AVNLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQGWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWNDEPLAAETSLMKEELLRVNRLGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFLLDNCLWQVVEDTFELLNRHTTKKEAQAP
>A0A3E3EFK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelatoclostridium ramosum|TrEMBL
MKIIDLLHRRPTLSFEIFPPKNHDGDISSIYQTIDELAKLKPDFISVTYGAGGSTTENTV
EIASKIKNEYSIEAVAHLSCIDATPEQLIRVLDSLKANNIENVLALRGDYPRGYDPMKAP
HYYKYASELNDFISKNYPDTFCLSGACYPEVHQEAASLEEDLIALKKKVDAGAEYLITQI
FFDNNYYYRLVREARIRGINVPIIAGIMPATNSKSLLNIAKLSGCNIPYNLSASIERFKS
NPQAMKEVGMNYATNQIIDLITNGVDGIHLYTMNKPETVHEILKRTSNILAEFKND
>A0A6G3T1I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces anulatus|TrEMBL
MALGTPSTRTDHALTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A6I3B9D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSIFSRLKKSSTDVSPAVKTLVSSMRYELIPMKSIEQAILDLPSGAPVSVTCSPVKGISA
TQEISARLIASGHEVVPHFAARLVESREHVQKLATWVREQGIKEVFLIAGDAEKPAGPYT
DGIELLRDFLDSNSGVSRVGFGSYPDGHAFISREALSTALYDKQKLLEEAGVQGLASTQM
CFDVAQIRQWIKTERDNGFSVPIQLGVPGVVDRTRLMSLGVRVGVGASMRYLSKNKASIM
KMLSPGGYDPTELVAGLAKDSQSLNIVGLHSFTFNSVADTAAWQREILATK
>A0A2H3FHX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella zeae|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WEAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPSADRP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKAIQDIAELFVSYLNNKIESLPWSESPLTTEADEIRDDLIE
LNKRGLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPV
ANGAVDTEPIANGTAVTAAAN
>H2PY11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pan troglodytes|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKKELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYE
EESPSRSIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELVNRPTQNARETEAP
>A0A5H8NJK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Hull|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2N7Q7U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacterium geofontis|TrEMBL
MEIKTHLQKVLESGIFAVTAEIEPPKNADPEVIREKARWLKGYVDAVNITDSPRATVKMS
SLASAVILIQEGIEPVMHITCRDRNRIAIQSDLLGASALGIKNVLCLTGDYISLGNHPQA
KPVFDLDSIQLLSLVKKLCEGKFFNGEEIKGKRPYFFIGAVENPFADPLEFRPIRLAKKI
KAGAKFIQTQIVYNLERFKKFINLCEEMGILERVYILAGITPPKSSKMLKYMKKNKVPGI
EIPDEIIKRMESAKDEKEEGINIAVEIIERVREIPGIKGVHIMAIGWESIVPEIVKRAKL
CSRPEL
>A0A505MAS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFELFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KKAKSFLTQHVYSQQILACVMPLTLGRATFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
SGKEFTPEITLFSCQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENSAVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILREKLIPTVPLETRGTSSWKNWYLATEA
>A0A1B1MGM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lincolnensis|TrEMBL
MTTLRELLATGERSYSFEFFPPRTDKGAETLWRAIRRIEPLAPAFVSITYGAGGSSRDRT
VEMTRAISAHTTLRPVAHLTAVGHSIGELRQIIGQYADVGVQDILALRGDPNGDPNGPWR
AHPEGLTYAHELVSLVRSCGSFGVGVAAFPEKHPRSPDWESDIRHFVAKCRAGADFAITQ
MFFDVEDYLRLRDRVAAAGCDTPVIPEIMPATDVRQIARFAELSHATFPEHLAQSLEAAR
GNEAAGHRIGVDHATAMAERLLHEGAPGLHYITLNKSTATLDIHRNVTGSRSAPHAVAVA
R
>A0A1B1M7P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lincolnensis|TrEMBL
MRDMLATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVKE
TQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNILAVRGDPPGDPMADWVAHP
KGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDSDVARFVDKCRAGADYAITQMFF
QPESYLRLRDRVVAAGCETPVIPEVMPVTSVRMLERLPQLSNAAIPSALKERILTVKDDP
AAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTASLEIYENLGLHHPPQA
>A0A8H8Z1X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas nitrosa|TrEMBL
MRSQKAFSPTFSFELFPPQTPEGIEKLRATRKQLAQFNPKFFSVTFGAGGSTRDRTFETV
SEILAEGHPVAPHLSCIGSTRENIFSILKKYQESGIRHIVALRGDLPSGMAQPGEFRYAN
ELVTFVRKEFGDTFHMEVAAYPEYHPQARSAQEDFKNFKNKIEAGADSAITQFFYNADAY
FHFVDMCEAANLNVPIVPGIMPINKFSQLVRFADTCGAEVPRWIRKKLESYGDDIASIHA
FGLDVVTELCERLLKAGAPGLHFYTLNSAVLTTKIWQRLGL
>A0A1W1DUK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MNISFEFFPPRTDKGKQTLAQVREELSVINPEYFSVTFGAGGSTQDATLETVLDIQKNDG
IPAAPHLSCIGSEKSKIIELLDQYKAAGINRIVALRGDIPSGVRDIGDFHYANELVTFIK
SEYNDHFRIEVAAYPEVHPQAKNIQTDLKYFANKVNAGADAAITQYFYNADAYFRFRDEV
EKLGIDVPIIPGIMPITNYTQLVRFSNMCGAEIPKWILERMKLYEDDLESLRSFGTEVVS
NLCQTLKNQGVDNFHFYSMNRANPSLLIAQNLV
>A0A0M7FEI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes faecalis|TrEMBL
MSNKQTLSLEFFPPRDIAAQEKLVRTAKTLMGLNPAYVSMTFGAGGSTRAGTVDAVALLQ
KLGFDVAPHLSCIGTAPAQLKEMLDNYRDQGIRRIVALRGDLPSGMGGDAGELRYASDLV
AFIRENYGEQFHIEVAAYPEMHPQATGFGDDLGHFVNKVNAGAHGAITQYFFNPDSYFSF
VERAQAQGVTIPITPGIMPITNSSQLLRFSTMCGAEVPRWIRLRLADFGDDRASIRAFGI
DVVARLCQDLLDGGAPGIHMYTLNGADASMAILPNLTWR
>A0A6A3XMM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora fragariae|TrEMBL
MPRVSSIHVTKQKERHEEADELAATKFVLDDSTVWTGLSTEDVNEALTLHGKALAMAKLM
NCRRERLERVKATRRGCCSGCTWCRVQNEFQLDVLLHLTCHLPTEQLKRALGLQRLKAKQ
DAGADFIITQFFFDVDNMIHWIADCKDAGITILPGYLSIQNYSSLCKFTSWCKTRVPESV
LAALDTIKNDDAAVRRYGTQLAAETCQRLLAAGVNSLHFYTMNLPRP
>A0A2N1NWN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus irregularis|TrEMBL
MKVINKILKAHEEGRPSWSFEYFPPKTQQGVQNLYDRMERMYRLGPEFIDVTWNAGGTTS
QLTSEIVATAQSVYGLETIMHLTCTNMPKEKVDKALKDAKECGCQNILALRGDPPRGQEH
WEACENGFSHAIDLVRYIRQQYGDYFGIAVAGYCEGHVDNPDKDDDLYRLKEKVDAGADF
IITQVFYDVDIFLNWVKKCRAIGISCPIIPGILPIQNYSGFNRIITLSKTIVPQFVLEEL
EPIKDDDAAVKEYGIRLAVDMIRKMFADGIKCYHFYTMNLERSTRLILEALEFVPPIENV
KPLPWCPSLSAKRKKENVRPIFWRNRTKSYIARTEAWDEFPNGRWGDSRSPAFGELDGYG
VSLKHSKKGALELWGYPQKHSDIFDVFVQYCRGEVNSLPWSDQPLAEESNIIREQLAHIN
SLGYLTINSQPAVNGVRSDHKIFGWGPKNGYVYQKAYLEVFISPTQLDALIARIERDTNI
TYYAVNKQGDLKTNTQSDGPNAVTWGVFPGKEIIQPTIVEAVSFTAWKDEAFELWNEWTK
IYDTDSISAKLITDIADNWYLINIVHNDFHDSDGIFKIFEQISVTDYEADR
>A0A7L4Q9V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccales archaeon|TrEMBL
MKAGSNIERLFDKGEFVVTGEIGPPMSSNPSSIQEHARHLKGFADAFNLTDNQTAIVRMS
SLASSVICLQEGVEPIMQMTCRDRNRIAMQSDLLGASALGVRNLLCLSGDHQTFGNQAES
KNVYDLDSIQQLMMLRRMRDESKVWGDTDIKEAPRVYLGAAANPFADPFEFRVTRLAKKV
KAGADFIQTQAIFDMERFERYMKEARSRGLHEEVHIMAGVVPLKSLGAARYMKNKVSGMI
VPDQLIDRMKGAEDPKEEGISICVEQIHHLLTIEGVHGVHIMPVAWEKKLPEIVERAGLL
PRPVL
>A0A815P062|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sordida|TrEMBL
MEFTVSDNQAVPNNHKINGVETHLQSTCDLNGFKRIESEGANISAKGCCLQPIKYVSLKE
KILKRIADHDRWYSLEFFPPRTPSGAANLIGCFDRIAAGQPLFCDITWHPAGDPASNKET
SSMMIANTMLNYCGIDTMLHITCYGAKKANMLEYLYKAKDCGIRNLLALRGDPLVGEEWD
AEKSDFRYAVDLVKFIRQHFGDYFVICVAGYPQGHPDSTSYEDDLSYLKKKVDCGADFII
TQLFFQPETFLKFESDCRAIGITCPIIPGILPIQGFASLRNIVRLAKLDVPKEILACIEP
IKDNDEAIRNFGVQTCLDLCRTLLESGKVDGLHFYTLNREFATIEILKKLGLWLEEQTLR
ALPWKKTSFSHARSKENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGALTDYH
LFYMKIDATRDELLDEWGRELTCEQDVWNMFACYVGGEKNSLNKVVRHFPWTDDELALET
GLIRKELVEFNSQGILTINSQPAVNGKPSLDPVVGWGTPNGYVYQKAYLEFFTNEGNIPV
LRAVLKKFPGVNYHFVNKSGEISETNADDEQPIAVTWGVFAGREIIQPTVVDPVSFMIWK
DEAFSLWTERWGKLYEQESCSRAIIDKIANTYFLVNLVDNDYPQGSCLWQILDSMFEYQK
LSNKHIDS
>A0A3G6JM50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus thermophilus|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILLALDDMKGSAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRELDAVGVNRILALRGDIIPGVEPLKDFRYATD
LIEFIKAEAPNFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIYAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETARHIYEATHSLFKHHSQVGAL
>A0A3V2YGT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella newport|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0N1EG01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. ST904|TrEMBL
MTSAQRPVQAPLLGCLPGDISVSFEFFPPKSEKMEEQLWDAITQLAPLDPSFVSVTYGAG
GSTRERTHSTVARLVRETELVPAAHLTCVGAGKGEIAEIADQYWEAGVRHIVALRGDPPP
SSGGVFTPHPEGYTGAADLVAGLKARHDFDISVAAYPEVHPEATSAEADLDNLKRKLDAG
ANRAITQFFFSTDAYFRFIDKVLAAGITAPILPGIMPVTNFTAIRRMSGNTEIPAWLETM
FEGLDERPGPRALVAAVAAADLCRRLYEGGVRDFHFYTLNRAEQAYAICQLLGLRPGTGI
>A0A167CXI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum incanum|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTAMGLSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKDE
YRDAEDSDVDDAEDFVWAVDLVKYIRKNYGDYFCIGVAAYPEGHADESHPQGQSFEHDLP
YLVEKVQAGADFIMTQLFFDIKAYDKFEKILREHPSGAFKDIVLLPGLMPIQSYQMIKRT
TKLSHAKIPDNLMARLDAAKGDDEKVKQVGVDILSELVEQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDPKFEDEEAVIDDGPGVPVSIPAVQLNGLSPVHPAARALSGRRH
SSMGSSDPHNRIIVSSASNPAYETTAAGLMVSEPVNTRANTLAISEGVGAVGREATWDDF
PNGRWGDARSPAYGEIDGYGVSLHMSVTQAIRLWGTPKTVQDINNIFIRHIKGQLSAIPW
SEEELLPESNIIQQELLELNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVEL
FLPSSDWAGLVARLNEVTDNTICFYAANAAGDFVSSDSSGGLVLEGTEASTNAVTWGVFP
GKEIITPTIIEEVSFRAWAEEAFKIWGEWAKVYGKGSESEALLERIRSEYWLVNIIHHDY
VERDALWKLLSGEKEN
>A0A2H3SJK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella fujikuroi|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIHDIALLFVRYLQNEIESLPWSEAPLTTEADEIRDELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKGLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A3E4LZ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ruminococcus] lactaris|TrEMBL
MKIIDRLNEDRINISFEVFPPKTDAGFANVQRATDEIAKLDPSYISVTYGAGGGTSKNTA
KIASHIKDDLHVLSLAHLTCASSTKEEVREVIRNLKELGIENILALRGDIPEGMKFPDGD
RFHYAYELVEEIRKQGDFCIGAACYPEGHVENEHKEDDIRFLKQKVDCGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLALLDRFGSSPE
AMMQAGIAYATDQIIDLLANGVKNIHIYSMNKPEVATKIMSNISEIIKC
>A0A7H8TGK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces chartreusis|TrEMBL
MALGTASIRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGDWVCHPQGLTYAAELVELIKASGDFCVGVAAFPAMHPRSVDWDADVRHFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAAGCDTPIIPEIMPIASAKTLERIPSLTNAGF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A0D0FHI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldibacillus thermoamylovorans|TrEMBL
MEDGRLVYESDEQYFYEAAIQFVKEGVCLLGGCCGTRPEHIRAMAEAVKNLSPVTEKKVI
KEKPIIQLIQIQQVHELSLVDIVKSRRSVIVEFDPSKTLPMSQFLSGVNALKNAKIDAIT
LADNSLASPQINNVACAQIVKNRYHLRPIVHLTCRDRNLIGIQSHLMGLHALGIHDILAL
TGDPTKLVSFPGASSVFDLTSFDLIRLIKQFNEGLSYSGTSLGEKTNFTVAAAFNPHVKI
IFSAKIRSSSGIEAYLSNFSVFTIA
>A0A0N4UK24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dracunculus medinensis|TrEMBL
MPESPLEIQNDEQIIYRYRAIDMIRWIREEFDDYFTIACADAPSYAADILYLKSKIEAGA
NFVITQLFFEVEVFEKFIRDCREIGITVPIIPGILPIQV
>A0A1Y5KVK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A139KVI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides intestinalis|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYDTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNRYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELTCEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A9TUK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Physcomitrium patens|TrEMBL
MTSAVATNTAMAGARSSIFEQHKFVRLLELPAATSSSLSPFLQNSQTSTINGFVTPDLPV
KTSLAEFLNSFELKHILPRLVQKSSKEETVQLPRLGLVETLRGLDCWQVRTVAAQTRLLP
EIQDRMVKASNNIEAAGCGGALLLLSGGHPLRRVWFANQLLPANSFAMLRAAHQLRKSGL
LSPGLQLWCVENPLLNSVERLDKKVMAGAEAVIVQPPLLPDRFEEWWSKAEHRGLTKATP
VVVGLPLLTSARNYSFWLELTQASGKEADAITARWKRIEAEYAGDSVAFARFCYEESVRM
IESIRCLPGVAGIHVMPVTRAGWRQYQKLVAEGKL
>A0A0G9MR70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantiacibacter gangjinensis|TrEMBL
MIAKALSADRLDPVEEQHKAHERPLFSGLPGDIAISFEFFPPKSEKMEAKLWDAVNELAP
LAPDFVSVTYGAGGSTRERTHNTVARLIAEAGIPAAAHLTCVDASKAETQKIAEAYWEAG
VRHIVALRGDAGEPGAPFVPHPDGYNNAAELVAGLKEVADFEISVAAYPEVHPDSDCPQS
DLDNLKRKIDAGASRAISQFFFSADTFFDFTDRCLAAGIYAPVVPGILPVTNVAQARKFA
GQCGAVIPDWMDGLFDGLDERPAARQLVAATVAAELCRRLYAGGVRQFHFYTLNRADLAY
AICHMLGRRPKDIAS
>A0A0T7D3H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio crassostreae|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSNEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A8D5GNC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus hoagii|TrEMBL
MTFDAVRGRNSAGFVTQTPSIVDRIRSSEASKSGRIPFSVEFSPPRDEAAEARLWRAVRE
FERLGPAFVSMTYGAGGSTRDRTVRVTGQLADDTTLLPVAHLTAVGHSIDELRAMCGAYA
DRGISNILVLRGDPPGDPLGDWVKHPDGVEYAEELVRLVRDMGDFHVGVASFPEGHYRAP
DLDHDTKYLVQKLRAGAEYSITQMFFDVEDYLRLRDRVVAYDREQGEKPIIPEIMPITSL
RSARRSLELSGSSLPPALEERLTRAAGDGPDENRAAVREIGIEVATEMSERLIAEGAPCL
HFITLNFARATGEVLANLGMSASASV
>A0A5H7K0F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Cubana|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A660TV10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MSKLQQSLKKGLFTITGEVGPPKGVNLEHCMEKEVEYIKDRVVAINVTDNQSSVMRISSQ
SVCSLLVQKGLEPILQITCRDRNRLAIQSDILGAYVQGIRNILALTGDHNTAGDHPDSKP
VFDLDSVSLLMTITSLKNGKDLAGQELDGVPEDIFAGATVTPGADPLEMQLIKMERKIES
GAQFFQTQAVYDPAVFENFMNKAQKYKVPVLCGIVIIKSPGMAKYMNNFVPGVFVPDNMI
KPLAEASKEDRPKKSIELMAEFIRKIKPMCQGIHIMAMGWEKYVPEMLDMCDL
>A0A6J6I4I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTQSAAGANLAQLLATGGRSFSFELFPPKTDEGEQALWRTVRDLERLNPTFVSVTYGAGG
STRDRTVRITAEIAEQTSMIPVAHLTCVGASREELRGVIGEYAAAGIHTILALRGDPPGG
PTAKWTPHEDGLQHADELVELIKALGNFTVGVAAFPEGHPSSPDLDTDARVLAAKQDAGA
QFAVTQFFFRSRDYADLLERATAHGVTMPIIPGLMPVTNVAQIARFADLSGAAFPPELAA
RFELVKDDDDAVRKLGVEIAVEMSNELLAMGAPGLHFYTLNRSTSTVQVYEALGLGSR
>A0A1Q8NLB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella dysenteriae|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2G7G5X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus arachidicola|TrEMBL
MHIKEKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAAEGGLRYAKDLVRYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLEAL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLNELKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIKDLSRLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLIE
LNHRGILTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDSWYLVNIVNNDFHNTYDLFELFKDLNVRDFDVEVAADNADLK
SPENETAETAAN
>A0A6J6SGP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARISDLLAGGRTCSFEFFPPKHEAGWLSLGRTISELEDLQPDFVSVTYGAGGSTRTKTA
DLVSWVRRQTAIAPMAHLTCQGHTRADIRDILMDYRAENVENILALGGDPPAHGADPVPS
DYRFSGELVDDIREFGGFSVGVAAHPELHPRSPDRLTDRRHLADKLQRADFAITQFFFDV
EHYRQMVDELADLGTTKPVVPGIMPISNLGQVTRMAHMSGAEVPEWVQKAMSKAGDDLDE
GERIGVELATELCARLLEAGAPGLHFYTLNRSWATRQIFANLNLRA
>A0A601EJ76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J6H3V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARISDLLAAGRTFSFEFSPPKSAAGSMSLGRTIAELEPLAPSFVSVTYGAGGSTREHTR
DTVLWVGKETNIPPMAHLTCVGHTKAEISDIISTYAGAGIENVLALAGDAPKDPADARPS
DYMYAIDLIEHLHEIGDLCIGVAAHPEGHPRSPDMATDRRHLADKLRVADFATTQFFFDI
EHYVSLVNDLADLGVTKPVVPGIMPVTNIAQVERMAELSGAAFPQWLRERLESGTTAEDV
RRIGVEAATELCAALLEAGAPGLHFYTLNKSTATREIYAQLGLPVA
>A0A7C2ZBP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobi bacterium|TrEMBL
MTSNGKNANFALYTNRSIVTVPPERTPFRERLHHPTPLIAVGSVEQETQSRIADRAELLA
LQAPLALEEVFGLFVQAGAELLLTPTERASRLWLAQLDRANKVYELNRKAVWIARKAATR
TAYVAGVIGPPPQMLQPIGPLTPELLRRALAEQAIALLDGGCDALVLKSFVELDELILAL
ETVAPLANGTPIIALKAFPEDGAVLATSFPADVARLLASHPVAAIGASGTVGPQRMHGII
AAMRQGTQLPIVALPDTSIPTNNRGTITYRSDTDYVARSVRHLVALGVRIIGTDRGSSVE
HIRAIAAALAAEPPEHIEPPSRHREAHLAPAQPALEPSGFARALQNRFITTVELDIPRGL
DMQSVLEGAAYLRRHGIDAVNISDGARARLRVNSIMLSAIVHQQTGIECITHLACRDRNM
VALQSDLLGAAMLGVQNILAISGDPTHIGDFPRATSVGDLDAVGLIRALRMMNSGRDLAG
NPLGGSTRFCIACACNPCAEDLERELDRLALKVAEGAEAVFTQPVFDVELWLRFRERVRT
LPARFIVGVLPLRSIRHAEFLHYEVPGMVIPGWARERLGRAPTSAAAAEEGIAIAAEFLA
AVRHHADGVYLMPPFRRYTVAIEVLRRVGIVSETGNP
>A0A0T5P494|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius indicus|TrEMBL
MKAPSVSFEFFPPKSLEASFRLWDTVQALAPLEPDFVSVTYGAGGTTRELTRDAVATLHK
TSGLNVAAHLTCVDASREETLAIADGFAEAGVNEIVALRGDPPKGSGGFTPHPDGFNDSC
ELISALAETGKFKIRVGAYPEKHPEAADSNADIDYLKRKIDAGADEAITQFFFEADTFFR
FRDACAKAGIDAPILPGILPIENWNGARRFAESCGTSVPAWLADAFEKAQAHDDGREDLL
AVAVATELCSKLIDGGVEHLHFYTLNRPDLTRDVCHALGVRSKVELRDVA
>A0A440DLU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDDMEARLWDTVTRLEPLKPQFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIREFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHSFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAVCHMIGIRSHEADVA
GSAAA
>A0A414K3Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLQELNEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFAHQPNFEVN
>A0A2D6CMW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MSSLSKALQSSDFVVTSELTPPKGLDLAPLLDKATLLKPHVSAINLTESHAARMAMDPVA
VGHLMLDHGVEPIVQMTSRDKNRLAIQASILGASALGISNLVFMGGDPPENGDHPDAKPV
FDLFASQLLGAVRALNSGTDLNGNALNKSTEIFAGAVVNPGASDPGAEIENLHRKIDGGA
EFFQTQAVYDVSAFSAFLDKARSSKPILAGIIPIKSVKMAQYMNERIPGVDIPDHLIEKI
AAAGDDKEAIAKISIGIAASTIRELRSVTRGGHVMAIGWEQYIPQILEQSQT
>A0A3A9HDV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides ovatus|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQKQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEIAKIIY
>A0A3S3DBA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A2S7USF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrosphaera saromensis|TrEMBL
MSFHNAQHLESINNNLLDIKGKIDVSFEFFPPNSVEMETTLWNSIERLTPLNPKFVSVTY
GAGSGTRDRTHDVIKRIQKETNLSTAAHLTCIDASKEELIQVAKDYWKHDVRHIVALRGD
LPDNSEKPHMYGSDLVTLLKSVADFDISVAAYPEVHPDARNAQADLINLKRKIDAGANRA
ITQFFFDVETFLRFRDRCAAAGIEADIIPGILPVTNFNTLKRFAGLTNVNVPNWIHDSFQ
GLDNDPTTRNMVGASIAMDMVKVLSKEGVKDFHFYTLNRSELTYAICHMLGVRPQAQP
>W5L444|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Astyanax mexicanus|TrEMBL
MVNQRLDTGWQPCKSDSSGGSNSGESSKESSRCSTPVLDTDRTDRLRDKMRRRIESGDHW
FSLEFFPPRTAGGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESILHLTCCKQTKEIITAHLNKAKRLGLKNIMALRGDPIGADWEEEEGGFNYATDLV
KHIRHEFDDYFDICVAGYPTGHPEAESYEDDLKHLKEKVDAGAHFIVTQLFFRAETFLKF
VKDCRAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGI
QQAVEMCRVLLASGDVSGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSSKEALLK
MWEEELTSEDSVYQVFTNYITAEPNKSGHKVMCLPWNDDPLAPETNMLKEELEKVNRRGV
LTINSQPNINGKPSSDPIVGWGPPGGYVFQKSYLEFFTSSENVNALLQVLKKYEPRVNYH
IVNVKGKNITNAHDMQPNAVTWGIFPGKEIVQPTVVDPVSFMYWKDEAFALWIEQWGKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIDDMFELLDAPPEPLDQENLQ
>A0A6I1HUD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium violaceinigrum|TrEMBL
MHPAQSRPSGNITHAYSLEVSAKDMPALSAATPRIVPASTIAIPYLPREDDDARLAAVRT
VRGLGFEPMPHLSARRIASLAGFESFVQRAVAEAGVERCFVIAGDPSTPLGPFTDSAALI
DTGVFERAGIKVIGVGGHPEGHPVMSTADQWNVLERKCRSIVQRGMTPLIVTQFAFDADV
VLTWLKALRARGIEHPVRVGVPGPASIAVLARYAALCGVSACASMWSKYGVSIGKLFGTA
GPDLFVERLAAGLTEAHGKVSLHFFPFGGIAQSVKWIEQYRSRPHPASG
>A0A557PBA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio algivorus|TrEMBL
MSYSHAGHIDALNHNIADLEGKINVSFEFFPPSSEKMEETLWNSIHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASRDELKEIAQDYWNNGIRDIVALRGD
LPPNGGKPDMYASDLVELLKGVADFDISVAAYPEVHPEAKNAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVSNYKQAKRFADMTNVRIPSWMAKQYE
GLDDDPVTRQMVGASQAIDMVRTLSREGVKDFHFYTLNRSEMTYALCHTLGVRPR
>A0A1S3V037|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vigna radiata var. radiata|TrEMBL
MKIIEKIRDAAADPNTVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANRMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVKHIRAKYGDYFGITVAGYPEAHPDVIGSDGLATAEVYQKDLEYL
KSKVDAGADVIVTQLFYDTDTFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPADIMSALEPIKDNEEAVKSYGVHLGTEMCKKILSHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALTDYQFMRPRARDKKLIEEWVVPLKSVEDIYERFRMYCMGKLRTNPWSELDGLQP
ETKIINEQLERINAKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKL
DTLVDKCKDRISLTXMAVNKEGSWSSNVGQTDVNAVTWGVFPAKEIKQPTIVDPVSFNVW
KDEAFEIWSRGWASLYPEGDASRKFVEEVGGSYFLVSLVDNDYINGDLFAAFADF
>A0A1S3UFT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vigna radiata var. radiata|TrEMBL
MKIAEKIRYAANDPNTVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANRMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVKHIRAKYGDYFGITVAGYPEAHPDVIGSDGLATAEVYQKDLEYL
KSKVDAGADVIVTQLFYDTDTFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPADIMSALEPIKDNEEAVKSYGVHLGTEMCKKILSHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALTDYQFMRPRARDKKLIEEWVVPLKSVEDIYERFRMYCMGKLRTNPWSELDGLQP
ETKIINEQLERINAKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKL
DTLVDKCKDRISLTYMAVNKEGSWSSNVGQTDVNAVTWGVFPAKEIKQPTIVDPVSFNVW
KDEAFEIWSRGWASLYPEGDASRKFVEEVGGSYFLVSLVDNDYINGDLFAAFADF
>A0A8J2UXJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Siccirubricoccus deserti|TrEMBL
MDQTLHPATGTLQRWLTGPRVGGLPNLAELPAPKLSFEFFPPRTEALEAQLWACIRRLEP
LQPRFVSVTYGAGGTTQARTHATVARIIRETSLTPAAHLTCVGAPRGEVDDVARAYWDAG
VRHIVALRGDAPAGVERYEPHPEGYAYAADLVAGLARVAPFEISVAAYPETHPTAQSAGH
DLDNLKRKIDAGATRAITQYFFDTDTYLRFLDRCAAAGITVPIVPGIMPVSNFVQMKKFS
AMCGAGVPEWMGRLFEGLEEDADTRRLVAAVVAAEQVRLLQANGVDEFHFYTLNRSDLVY
AIAHLLGARPAAPGQA
>A0A8C4XS28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falco tinnunculus|TrEMBL
KESDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDAGDKWFSLEFFPPRTANA
AVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCN
QTKDDITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDI
CVAGYPKGHPEAESYEADLRHLKEKVLAGADFIITQLFFRSETFLKFMKDCQAIGITCPI
IPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDS
GMVHGLHFYTLNREVATTDVLKRLGIWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPK
SYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVF
EVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNINGKP
STDPIVGWGPSGGYVFQKAYLEFFTSSEIVMALLKVLKKYELRVNYHIVNVKGQNITNAP
DLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYI
HDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQE
>A0A3A4K1B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MMSNSNLERVLSSGNFAVTGECGPPRGIDAEVVRSKGKILKGYVDACNVTDNQTAMVRMS
SFAACVILREMGLDAVMQMVCRDRNRIAMQSDILGAAALGINNLLCLSGDHQRFGDHPGA
KNVFDVDSIQLVSIAKKMRDDSTFQGGKPIKQGAPKLFVGAAENPFADPFAIRVPRLAKK
IAAGASFIQTQCIYNVERFAEWMKGVRARGLHERAYILGGVTPLKSAKMAAYMAKGVAGM
DVPQHYVERMEKTPKEEQKAEGIKIAVETIQQLREIEGVAGVHLMAIEWEEAVPEIVKMA
GLYPRPQLAAGN
>A0A2R7JYS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. HMWF008|TrEMBL
MMVSVKQMEEARHALTTPLFADLAGDARISFEFFPPKTEKMEETLWQSVQTLSPLGPRFV
SVTYGAGGTTRERTHATVARIARETDIPAAAHLTCVAATRDEIDAVADAYWQAGVRHIVA
LRGDSPVPGEKFQSPVGGYANAVELVTGLRKLHPFEISVSAYPECHPDSVDAAADIDNLK
RKLDAGATRAITQFFHEAETFFRFRDAATKAGVTAEIVPGIMPIMNFGAVQRMSAMCGTV
VPPWMGTLFEGLDDHPAARQLVSATIAAELCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GIRAKAPVAAHAEAA
>A0A3D1QXS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MRIRDRLEQSRPCFSFEFFPPKSDLAMDELFQTVTDLAPLAPGFVSVTYGAGGGNRDLTV
EVITRIRRILGVEVMAHLTCAGHTRAELVGLLERLRDEGLENLLALRGDKRPDDPSSTLE
EGLSHASDLVGLIRDRGFCFCVGGAAYPEGHLECASRQVDLRNLKRKVDAGAEFLITQLF
FDNAFYFDFVERARRVGIGVPIVPGIMPITNLAQLDRFTRFCGATVPMRLRLELERRQND
PSAILQLGVAHATVQCMELLNRGVRHIHFFTLNKSPATC
>I2NV07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria sicca VK64|TrEMBL
MNRGKHNGNHIKIIHKLSENFEFDSYTRQIYHTSLKTFKKDNRGTQPMSYAKEINALNNS
LSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGANSGERDRTHSIVK
RIQQETGLETAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEPPGYEKKPFYAEDL
VKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVITQFFFDVERYLRFR
DRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGLDDDQGTRNLVAAS
IAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A1A0XPP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp. 852002-50816_SCH5313054-a|TrEMBL
MSQASPYTGPVNSSAPVPSVVERLSAPHPGQVPFSVEFLPPKDAEGEARLWRAVRVFERL
NPAFVSLTYGAGGSTRDRTVRIAGQLATETTLVPVAHLTAVNHSIAELRSLVGAYADKGI
TNILALRGDPPGDPLGEWVKHPEGVSYAEELVDLIGGLGQFHVGVASFPEGHHRAPDLDH
DTRVLVSKLRAGAEYSVTQLFFDVDFYLRLRDRVAAADAEQGAKPIIPEIMPITSLASVR
RMVELSGSVLPESVERRLIAAAGSGEQEDRAAVRAVGIDIATEMSQRLIAEGVPGLHFIS
LNFAKATCEVLDRLGVDTSDALPLVSSN
>V8LVT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus thermophilus TH1435|TrEMBL
MTLIKMFLSQQKSKTKKVKLMTSQTPSLSFEVFPPNPAVGNKKILLALDDMKGSAPHFIS
VTASNNKYNIKETTVPLADHIQNDLAIPTIAHLPAIYLSKEKVADTLRELDAVGVNRILA
LRGDIIPGVEPLKDFRYATDLIEFIKAEAPNFDIIGACYPEGHPDSPNQISDIQNLKKKV
DAGCSSLVTQLFFDNERFYDFQDKCTLAGIDVPIYAGIMPILNRNQALRLLKTCENIHLP
RKFRAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNAETARHIYEATHS
LFKHHSQVGAL
>A0A165LRB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelodictyon luteolum|TrEMBL
MLVKEILNTAEKPVFSFEFFPPKKDEDWETLFDTIKALSPLNPSYVSVTYGAGGSTRTRT
HDLVTRIQKETGLSVVSHLTCISSSREETGTIMENYRQHGINNVLALRGDKPAGAATLAE
AIKDFPHAIDLVRFIKTNYPDFGVGVAGFPEGHPETPNRLTEIEYLKEKVDAGADYIVTQ
LFFDNRDFFDFRDRCRLAGITVPIIAGIMPVTTKKGMIRMSELALGARIPAPLQEKVMAA
SSEDEVASLGIEWATRQVQELVDNHVRGIHFYTLNMADATLRIFRNLHA
>D9WNY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces himastatinicus ATCC 53653|TrEMBL
MTAPPRTYPTGRDLAEPPATASATRARAPRRNLAEVLAAGERSYSFEFFPPKNEAGERTL
WNAIRRIERYAPTFVSVTYGAGGSSRDRTIGLTKRMATETTLRPVAHLTAVGHSIGELRN
IIGQYADAGILDVLALRGDPPGDPRGPWLAEPDGLTYADELVALIRESCDFSIGVAAFPE
RHPRSPDWDSDIRHFVAKCRAGASYAITQMFFDAEDYLRLRDRVAAAGCDIPIIPEIMPA
TDFRQVRRFAELSDAHFPDDLARRLEAAQGDADEGRRIGVDHATAMARRLLDEGAPGLHY
ITLNRSTAALEIHRNLAPRPVRHTPR
>A0A842HKK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruficoccus amylovorans|TrEMBL
MLTAGEPVFSVEFYPPKTEEGARQMLRTAKSLSAFRPDFVSITYGAGGSTRERTLEYGEL
MRDLFHFEVMPHLTCVGHSRDELAAMLERFQQAGFRNIMTLRGDPPKGKTDFQPHPDGLA
HASELVAFIRERFPHFCLGVAGYPEKHPEAPSLESDLAHLKHKVDQGADFITTQLFFDNA
DYFVFVDKCRALGIEKPIIPGILPALSLDQVTKFCGFCQAKLPSGLVRRLEAVAGDEDAE
RRVGVEWAHEQVKQLLEAGAPGVHLYILNRSASAIDLVQALHNDGILRA
>A0A6N9E0D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0677_bin_15|TrEMBL
MTPRTLQHTLVQGQFAVTVELNPPKGTDVSELLETAKSLSGRVHGINVPDNAAAVLRASP
VAVARLLYEQGHDPVLQVTCRDRNRLALQSDLLGAHVLGIRNVLCLTGDSPGTGDHKDAK
PVFDLDTVQLMHAVQELNEGRDLAGNALEGRTAFFIGGAAAPGAEPAELLHKKFEAKVNA
GAEFFQTQPVFSAKVIHPFMEAVRPYSRKVLAGVLVLRSVKMAEYVNARVPGIDVPDEIL
QELRNAGDARVSEAGLEIAVRTIRAVRPFCDGVHLMAGRLAHRLPEIIRKAELS
>A0A6S6LWR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrifermentans bremense|TrEMBL
MGGSFLERVAHEVLIGDGAIGTMLYAKGVALDANFEHLNLVRPQLVLDLHAEYLSAGAQV
IETNTFGANYAKLSAIGIGGKVAEINRQGAILARRAANGRDVFVAGSMGPLGRGKQEQSD
EQVQESFRLQAAALAEGGVDLLILETFSELDELETALAAARETGLPVVANLAFGEGSRLA
GGIEAEDAALRLAAAGASLVGANCGAGPLELLATLKRMAAVTDLPLAAYPNSGFPEYVDG
RYIYRTTPDYFAARAEEMVAAGAVLVGGCCGTTPEHIRVMAQRLKGARPAARVAVGAVSR
TPVAEKAQALGSSFLDRWGKEMVVTVELDPPRGLDCSRILAGSRALKEAGADAINLAENP
LARVRMGNLALASLIRREVGIEVIAHITCRDRNLIGLQSDLMGASLLGVSSILAVTGDPA
SLGEEAGASSVFDLNSFTLIKLLSDLNRGVNALGNPIGAGTGFTIGAAFNPNTQKMEVQV
ARLAKKVANGACFAQTQPIYDLERFEQMMEQTAHLGIPVLPGVLPLVSGRNAEFLHNEVP
GITIPDSIRERMAGKVGEEGVREGLAIAREFIEATMGKVGGYYLIPPFGKYEIAVELVKF
IKSRG
>A0A3D1AN26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKSGSRLERILTSGEFAVTGELGPPKNGNAELVREKARLLKGSVDAVNITDCQTAIVRMS
SISAGLLTLAEGVEPVIQMTCRDRNRIGMQSDILGAAALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDAIQLLGMVKDMRDDKKFQCGEAIKSHEPRLFLGAAANPFAAPSEQFRAARLAK
KVANGADFVQTQIIYNVERFARFMQAVRDLGLHKKVHILAGVTPPRSVGMARYMQSSVPG
MDVTDEVIKRMQGAKDKEDEGINICVDIIRQVREIEGVAGVHIMAIEWESVVPEIVSRAG
LAARPVFADEPVALAAPVSAIEIRNTVAGGEESDAVLAVAKVEAEKIIAAARVEAAQYRA
SATTGGAGVVGQARVEIDEAGEDAMNEKERQMALESVRLGLDALKKAYGLSDDQFDALVK
FAGAEAILKREPLLATPVLAAATPVAPAAPAIDESVARKVAEIAAAEKAKKAEAAKKEAD
EKAAAEAKKVAAAAAEEAQKAEAAKKAAEAKAAEEVKKTAASEPQKVAPAVSASPTGAVD
AADLACEKTPLSERAAKVPEASYKQAYTGAIRQTVLGGEARGIKVGGATTLSFHLFEGSM
PNRPMIAFDVLDVKPDEWPDSLARHYQDVLDNPLAWAQKCVKEYGADAICLSMVSTDPNG
LNRPAGEAARAAAEVVKNIEVPVIVWGCGNGEKDTETLREITSLIGDKKVCLAPLSDSNY
RAIGATAMAFHYPMVAASPIDVNLAKQLNILLENLGVSLDSVLIDPSIGALGYGIEYTYS
VMERIRLAALTQKDEKLQVPFVCNLGREVWKAKECRLPSDALIGDQETRGILMEAITASC
MLMAGGELMIMRHPRAVALTKSLINGLMG
>A0A806P780|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus polymyxa|TrEMBL
MKPDLRTVLNREIIVGDGAMGTFLYQLGFPVNTSYEELNITSPDVISDVHGQYLNAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIAKAAAGPEHYVVGAVGSICGGKRLNISK
LELSRNYEQQIDALLSEGVDGILCETFYSLDEMRIALHSVRKYSDIPVICQFAVDQVGRT
QDGFLVSEAFSTLRSEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAASFVDLGTRLIGGCCGTTPDHIAAISKALKNLQPPPLAPKEALS
TESIHVVEQTANEGGRGNGRHASEPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHALK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYIMTQPVYDPELIIAIAEETRHLEIPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGPEGRAMGVSIAKELLDTAMEHFNGIYFMTP
FMFYEMTAELTSYVWEKSGRAQAPLFRL
>A0A525CLJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MTELITKSRLEKVLKNGHQAVTSECGPPRSSDPAHIIEKGNLIKDYVDSVNITDNQTSVT
RLCSLAACIHLKQQGIDPVLQMVVRDRNRIALQSDILGAASFGIHNILCLSGDHQSFGDN
PQAQNVFDLDSMQLVQTVRHMRDEGKFLSGDEIKVPPDMFVGAAANPFGDPFKIRVPRLA
KKVACGAEFIQTQCIYNVDKFEKWMEGVRDRGLDEQVYILAGITPMRSVGMARYLSKNVP
GMDVPEELIERLKGVEKNKQSEEGITIAVETIQRLKEVKGVAGFHIMAIEWEEKVPEMVE
RSGLYPRPAVD
>A0A1Z7Z3N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium 42_54_T18|TrEMBL
MKSQQQYKPRFSFEFFPPKTDVGVKKLGAVREEFATLDPAFFSVTYGAGGSTRDRTFDTV
MDTKSSTGINTAPHLSCVGDTREQLRGLINQYKDNDINRIVTLRGDLPSGMGSSVGELQY
ASDLVSFIREETGDNFHLEVAAYPEMHPQATSMEADLQAFKTKVEAGANSAITQYFYNID
AYKFFIDSCEKMGINIPIVVGVMPITNHDNLMRFSNMCGAEIPRWIRTRIENHATDLDYI
TKFGEEVVTNLCEQLLDLGAPGLHFYTLNQVEPSLSIWNNLGLSNK
>A0A5C4NGX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium lividum|TrEMBL
MHHDMRKPTSNITHAYSLEASTKDIAALSAAAPRILPGSTISIPYLAREDDDARLAAARA
VRSLGFEPMPHLSARRIASLAGFESFVQRAAAEAGVERCFVIAGDLPTPMGPFADSAALI
DTGVFERAGMQVIGVGGHPEGHPVMSKAEQWEVLERKCRSIEKRGMAPLIVTQFAFDADV
VLTWLQALRARGITHPVRVGVPGPASIAVLARYAAVCGVGACASMWSKYGVSIGKLFGTA
GPDLFVDRLAAGLTEAHGKVCLHFFPFGGIAQSVKWIEQYRSRTDPGP
>A0A4Z1IF51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryotinia convoluta|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHYIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAAL
EEVKNDDAAVRNIGKDLVAEMCRRILEAGVHHLHFYTMNLAQATRMVLDELRLTPSNQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVNYLENGIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHEP
DLTYYAVKKTGDLQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLNESFETSENGD
VDGVRFIEPQTVPLTNGEANGH
>A0A1D9MMJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boudabousia tangfeifanii|TrEMBL
MVSFELFPSRQPSPDSSTWTQIHRLLAIAPDYASVTFGASGSAAEGSLEVIKEVQAAGLP
TLSHLTCVQRTRSELADLIKRMMDQGVRDFLALRGDPPRGETEWKAPTGGLNYASELVHL
LRETSQSHLGDAKAIDICVAAYPAGSPAAREDTLDALGQKAAAGADWAITQVFFESADYQ
QLLDSCAYRGINLPIVPGVIPFTDLKRLNRLQGLTGVEVPEKLRTLLTEPDPQLRTRHGI
RATLEFIADLLDAGAPGIHLYTFNRTRPALDILEYLRVRQWRPQTDLENLANDELLAQCL
RRLPPVL
>A0A0S7XLM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium DG_23|TrEMBL
MSNLSESLADGKFTVTGEIGPPKGVDTDEMFHEAEYYKGVVAAVNVTDIQSSVMRLGSMA
VCHQLLDMGIEPVFQMTCRDRNRLAMQSDLLSAYVLGIRNVLAITGDHVALGDHPQAMPV
FELDSVQLLKVIAGLEAGKDMAGNDLAGAPEFFKGAVVTPCADPVEPQIIKLEKKVAAGA
QFIQTQAVYEPGRFEEFMKKVEHIDVPILVGIVLLKSAGMAKYMNANVAGVVVPDEMMEE
MASVAKEDRQKKSVEIAARLIREMRLMCQGAHIMPLGWDSLVPQVLKEAELL
>A0A072P538|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala aquamarina CBS 119918|TrEMBL
MDDDRLPALLSALPPSSNYFSLEFFPPKTSSGFSNLQARLVRMTAALRPLFVTVTWGAGG
STATKSLELAEVCQRQLGVPTVLHLTCTNMSRTAVDDALEGAKEVGIRNILALRGDPPRE
EYRDTDENGSGGSGTDSNVDFTWAVDLVRHIRRKYGDYFSIGVAGYPEGHADESNPEAGK
QNVEHDLPYLEEKVAAGANFIMTQLTYDVNAYRSYEKRLRGYIAKDGRKLFENIPIIPGL
MPIQSYQIIKRITKLSHATIPEDISKRIEAVKSDDEAVKKVGVDVLSEIVEQIKDSPQPK
AVPRGFHFYTLNLEKSVAFILERTELIPTMSEPSPGESSDSDAIADDEKLNAYASSRLAG
QPAGEARFSRRRASSMNAQPHNRVITDHQTVVPVQRTTLAPNSQDSRPLLAQHEAAGRGA
GIPAGDPTRKHSLLISEGQGSLGREATWDDFPNGRWGPSHSPAFGEIDGYGPSLKVGPVT
ARKLWGRPKSSKDVTDLFRRVVLGQLEAVPWSDDIDPDSAGTGGGALRAETKIIQSNLLD
LIEKKGYWTLASQPAVDGAKSEDATFGWGPPGEGFVFQKAFVEFFCPKSEWETHLRPSLI
SHGEEKVGWMKTDAQGVFESSEQVARKQQEVDRPAPASKRTPGVHGVSAVTWGVFRGKEI
ISPTIIESESFKAWGEEAYSIWSEWRRCFPRGSDEEKLLEGLRRGFVLVNVVGQNYIGGH
TGLGAELWNILLGESGSG
>A0A2D8NTV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinicola sp|TrEMBL
MSTQPPLGFSFEFFPPNTDAGREKLGGVRDALAARKPRFFSVTYGAGGSTQARTFDTVRT
VRRSGVTTAPHLSCVGSDKAALRDLLHAYREDGVDSLVALRGDLPSGMGGGGELRYANEL
VEFVRDETGDHFEIAVAAYPEAHPQAPSFERDLENFARKARAGANIAITQYFFTAEAYFH
FVERVRAMGIDIPIVPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDSDSIQAFG
TEVVSNLCRRLLDGGAPGLHFYTLNQSAPTLRVLDNLS
>U1GJS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endocarpon pusillum (strain Z07020 / HMAS-L-300199)|TrEMBL
MHISGKLAASYEASKPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
QLTCEMVNAAQTHYGLETCMHLTCTDMGKEKVDQALQQAYKAGCTNILALRGDPPRESEK
WKATEGGFRYAKDLVSYIKSRYGNHFDIGVAGYPEGCDDQDDVDLLIDHLKQKVDAGGTF
IVTQMFYDVDIFLAWVKKCRERGINVPIIPGIMPISTHASFQRRVDWTRCHVPDAWNAAL
EPVKNDDAAVREIGKGLIADMCRKIIDAGILHLHFYTMNLAQATRMILEHLSLTPTTSGS
PLFKPLPWRQSLGLNRRDETVRPIFWRNRNTSYVARTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANTKLWGQPSSLQDISRLFVRYLNGELDRLPWSEAGISPEADSIKPELL
SLNERGLLTINSQPAINGVASNHPVHGWGPANGYVYQKAYLELFISPNLIETILERIIAN
KDLTYYAVSKNGELRTNTRDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAYRLGDD
WSRCYPSESSHRRLIEGLMNEWFLINIVNNDFHQEKEIFRIFDGLQVDDMDKVVEGQPCT
NGVQSNGTPEEAKQDRPIEANGTVVEMNGSAERKPKPKPKPYTGAEFTGASQLRN
>A0A1Q6A4D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter polytrichastri|TrEMBL
MKITEHIANAKGKTLFSFELLPPIKGSNLQGIFNAIDPLMEFNPPFIDVTSSREDHLYKE
HASGLLEKVTFRKRPGTVAVCAAIMNKYKVDAVPHLICGGFTKEETEYALIDLQFLGIDN
VLVLRGDARKGDAGFVPTPGGHCYATELLEQVTNMNNGIYLHEYQDTSFKTDFCIGVAAY
PEKHFEAPNLKTDFKYLKQKVAGGAEFIVTQMFFDNSKYKEFVTQCRENGINIPIIPGLK
PLTTAKQLINLPKIFHIDIPEDLSDAVQACKTDKDVKEVGIEWMINQCKELVEFGAPVLH
FYTMGNAEPTKRIAQEIF
>A0A5N5IQA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda hadalis|TrEMBL
MKITDHIKKANGQTLFSFEIVPPVKGKSIQELYKNIDPLMEFKPPFIDVTTSREEYIYKE
KDGLLDKKLTRTRPGTLGICASLKHKYNVDTVPHVLCGGFTKEETEYLLVDCQYLEIENV
MALRGDARKEEKYFTPTKGGHQYATELVKQIQDINEGNYLHDTIEASDLSSFCIGVAGYP
EKHMEAPSLQSDLKRLKEKVDLGADYVVTQMFFDNQKFFAFVEAARAMGINVPIIPGIKP
IAVKNHLQLLPQVFRVDIPQDLIDAVEACKTNQDVRKVGVEWAIQQSRELREYGVPVLHY
YSMGKSDNVEAIAKELF
>A0A380KMI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus infantarius|TrEMBL
MSGLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPEKVLAIHKAYINAGADVIQT
NTYAAKRHRLGGYGYGDKIKEINQAGVKIARQAAGEDTFVLGTVGALRGLKQCELSLDEI
IKETLEQVGYLLETKEIDGLLFETYYDEEEIIEILKAVRPLTKLPIITNISIHEAGITEN
GRPLVEIFGKLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAIKGLKPVSRKFVTP
MVEEAELIKAVKQSETIVDKVNRKVTIIAELDPPKTLDIRKFTKGVKALDEAGVSAITLA
DNSLAKTRICNVSIASLLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIKQLNKGIGYSGASIKKETTFTAAAAFNPNVKNLS
RCGRLIERKIAAGADCFITQPIFNSEIIENLAKLTRDYETPFFVGIMPITSYNNAIFLHN
EVPGIQLSDNFLAKLEAVKDDKEKCQQLALEESKQLIDHALKFFNGIYLITPFMRYDLTV
ELVEYIHQKVEQSHQIIP
>A0A6M0SIT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbyaceae cyanobacterium CCMR0082|TrEMBL
MSTSNGFHSAPSLLRSAIANHKFIITAEVMPPKGGNPSHMIKMAQLLKGRVHGVNITDGS
RAVLRMSSLASAVLLKQADVEPICQMACRDRNRIALQADLMGAHALGIHNVLALTGDPVK
AGDHPKARSVFDLESVRLLRTIGQLNQGIDLNEKKLPDGPLNIFAGAAIDPQSPSWSGLQ
KRFERKVEAGAQFFQSQLISDFERLEKFMSQIAAQAQKPILAGIFLLKSAKNAAFLNRNV
PGVHIPDDIINRLATAKEPLQEGIAIAAEQIKLAQSLCQGVHIMAIRREDLIPEILDRAG
IGPIDKPKTSMETPQPLEFPVLQN
>A0A6V7UUE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meloidogyne enterolobii|TrEMBL
MNKIQYNNSLLNKLNLINSTDGPFFCIEVSPPKEINKINNFISSINKLINNTATNNSFLF
LSIVAHAENNPTDLSLPNSSTSIASKILNEDILPKNSHLILHITGKSFINFPHSFVDIYF
TKLKQLGINNYFVLSGDSPKRENYNYLNYNLEIFPKSPQLDSLHLIKRIKSNKLSTNNNN
NLLTFAVAGYPECHPFAYNRNTDILFLKRKICEGNANFVICQFSFERGAEKFFQFVADCR
QAGINVHFIPGILLFQSFSSLLRFSSLTKIKIPQEMFNLLSSHRYNDDLIKYYSLWLAYN
ICQKLLNKSVLNNIRAIHLFNSNQWEMTRYLLYLLIRRNIYFLVLYLSNLDFY
>A0A2H1WIX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spodoptera frugiperda|TrEMBL
MEGTIKLTDLIQNKGNFSYSFEVTPDVSEEDIDNLKVEPLFFSVTWHAKMHQCKDLSIAP
LKTALQLKSKQKNVLLHLSCDMMTTTYLTDLLAMLQENGICNLFLVLGEGFYPGKSDFIN
TIELIKFIREKTGQYFCIGVAGHPGCSDEKLKQIKQKVDAGANFILTQAFFDVGVFKNFK
ERCEKIGVRVPLIPGVFSFETPRQLDGFVKMCKIKVSEDLLKAVGDNEKMNKPCTDIIKE
LIKQLNSICNITHYHFFTINKLNDVQKVIEELKQ
>A0A8D9YTL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus C101|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A6J1ZGL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinonyx jubatus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEASSGRFSVPPSISISHLTLPLRVLAACPLTLLPSTP
CSRNPAMVNEPRGDGGPTSRSEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRMES
GDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIAST
AVNYCGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYA
ADLVRHIRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADT
FFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIR
NYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHP
KRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPRE
ELLKMWGEELTGEESVFEVFACYLSGEPNQNGYKAYLEFFTSRETVGALLQVLKKYELRV
NYHIVDVKGEKITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWG
KLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A0M8SGR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WM6368|TrEMBL
MLAQGRRTFSFEFFPPKTDAGERTLWAAIRRIEALAPSFVSVTYGAGGSSRSRTVEVTKR
IAAETTLRPVAHLTAVGHSTAELRHIIGQYADAGIRDILALRGDPPGDPKGEWMRHADGL
THAHELVSLIRRLGDFTVGVAAFPERHPRSPSWTEDIRHFAAKCHAGADYAITQMFFHAE
DYLRLRDRLLAVGCLTPIIPEIMPATDFRQIRRFAELSDARFPDALAQRLEAAKDDPAAG
HRIGVDYATHMSERLLAEGAPGLHYITLNKSTATLEIHQNLNPSHDPATTITE
>A0A1G7DQ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Auraticoccus monumenti|TrEMBL
MPVRRLTPQQPSVGDLLATAERPLVSFELFPARNDEEQTVLWRTVRELEALGPDFVSVTY
GASGSTRDRTVGATEAIARHTTLRAMAHLTCASQTRAELRHTIGAYADVGIRNVLAIRGD
MPGGPSVPFETHPGGLANATELVALVRELGDFCVGVAAFPDLHPQARDADLDARVLVEKA
RAGASFAITQLFFTTERYVDLVRRVRDLGCDLPIVPGIMPVTRLGQIKRFAELSGADLPG
WVVDRLNAVGEDPKEVRRAGIDIATELCEELLEFGVPGLHFITMNRSQATRDIHRRLLSG
RAADRLRGTGARQDAVTTA
>A0A4S4BGD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella fermenti|TrEMBL
MLNHKIDNRQPGILTYGLTPPKTNHEPGKIAEIARRQIERIQDIGIDGLVLYDVQDEADR
TDQDRPFPYLSAMDPTEYSKNYLDAFDVPKIIYKVVGKETPEELARWIESDRTEDRFSVF
VGASSSKQEVTMRLPDAYRISKERNEKLRFGGVVIPERHKAKGDEHLRVAGKQQNGCSFF
ISQATYDVEASKNFLSDYYYYCSDNDIPMVPILFNLAPCGSLKTLEFMKWLGISIPRWLE
NELLHAQDILDNSIRSSCEVFGELFDFGLEKGIPIGCSIESVSTRRVEIEAAVELAKDIK
AFMRGRLRGTIGVGRR
>A0A4V3INW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT1-1|TrEMBL
MSACNARPAFSFEVYPPKSVAAASALTRTIDHLAAAGPEFISVTYGANGSSRNSSLDVLR
YIKDHTSVDAMAHLTCVGSSHADASRLIREFLDAGIDSFLAIRGDAPQGTVEGDTTFLGD
LHSAGELVQLIHRVQTERVPYTETVIPGLPGARGVKTERSKVRIGVAAFPNGHPNSRSIT
QDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVFFPILPGIMPVTSPNRLRRI
LQLSGEKLPAELSIELEVEPTEEGQRQIGIDYAVRLGQDVLAGGAPGLHLYAFNQHDTVL
SILEGCGARTVPAAMP
>A0A124GUW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces curacoi|TrEMBL
MHTAGLRALLHSVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLAARLASH
GYRVVPHVPARLLRDDLHLKDVTGRLREAGVDDIFLPAGDADPPAGVYDGALPVLRRLSE
LGGPFAHVGVTGYPESHPLLHDDVTVQAMWDKREHATYLVSNLCFDPRVLGEWITRIRRR
GVALPLYVGVAGPVQRAKLLAMATKIGVGESTRFLTKHASWFARFAAPGGYAPERLLIRT
ERALTAPSARVAGLHLFTFNQIAETERWRRALLDRLGR
>A0A840QM96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Texcoconibacillus texcoconensis|TrEMBL
MGFRDVIESRILVGDGAIGTLLYQDGMEGCFEEYNVTAPDQIRAVHQQYIDAGADLIQTN
TYAANSLKLSRYRLEQQTEAINRQAVRIAKEVAPEDVFVFATIGGIGNAFQNEFDVDEMR
QSLEEQASTLLNEDVDGFLLETFYDLEELTLLIEFLRERTDKPIIAQVSMGDIGVLQGGV
KLEDGLKQIEKAGADVAGVNCRMGPHHMLQSLEEVPLLDHAHLSVYPNASLPNVRDGRFF
YQSNPAYFKEMTKPLVGEGVRLIGGCCGTTPEHVRSVREAVDVAGLTPITEKNVQKRQGQ
PVAMDAAPRQDEPIPEITKTRTSVIVELDPPKSLSLIPSFMEGAEVLAKAGADAVTLADN
SLASARIDNFSLGMRMKQETSARPLLHLACRDRNMIGLQSHLLGLHAAGIHDILTITGDP
AKVGDFPGASSVFDMSSQHLMKLVNQLNEGVSFSGKDIGEKTSFSVAAAFNANARRLDRE
VLRLEKKIEAGADYFMSQPVYSPERFQEIYEATKHLPVPIFIGIMPLVSARNAEFLHHEV
PGISLTDEVRDRMAAVAGDREASEREGLAMAKDLLDAAQEYFNGIYLITPFLRYQMTAEL
TAYALNKEYDNEMTVQ
>A0A822J164|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon|TrEMBL
MITAEISPPKGTDTSRMVRDATLLKDMADAVNVTDNQRAVMRMSPLAACSILQEKGFETI
MHITCRDRNRLALQSDLMGAWALGIRNVLVMSGDHPSKGDHEGAKPVYDLDSVQLLGIIQ
KLNQGIDLSGNKLEGRTDFCPGAVTNTELGEAGLLKLRKKIKMGASFLQTQAVFDVTRFS
EFIEKTDEIRSKQSKQIKIIAGVIPFISERSALFLNKVPGIRVPDDMIKQIKDAKNPEIE
GMKITAEIIKELRTMCDGVHIMPIGNHENTGKLLEMAGLI
>A0A662RVZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon|TrEMBL
MKMAERKAFSELMKKIEAGEFVYTGELEPHRSIDISDVVSWAKTLKETGRIVAANVTDNP
RSDSAISSLVASYLIQKETGLEMIYQLRTADRNRLALISDILGAAALGLKNILALTGDHT
KTGTTPSAKPVFDLDGTNLIRLVRSLVDEGKDLWGNEIHGPRPELNVGGAGNPGMEPLEA
EVFKLERKAEAGADFFQTQVVFDAEVARRFLRAIEHIGVPTLIGIFPPRTYAQAEFFDKF
VPGVSVPREFMEKFAKLKELPKEKRKEKINEFNVDYFVSFIKEIKKEKACAGCHIMAVGY
PDVIGPIIEGVEK
>A0A061NCG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomicrobium sp. JCM 19037|TrEMBL
MKFIEALQKTIIIGDGAMGTLLYSQDITGSIEQANLYAAEQVYEAHLEYVKAGANLIQAN
TYAANRLKLKNYGLESQVTRINEAGVELAKRAAAHSDGTYVAGTIGGIRDGRSSEWTDEE
IDDAILEQTKALLASSPDVMLLETYYDLHELIRAIRLIKEQDASIPIVANVSLGDVGVLH
GGILLQDALQRLQSEGADVVGLNCRMGLLKRLHPLKRVIIPTDLLLSAYPNASLPGIRDG
RLVYQSNPNYFKSQAVSFRNLGVNLIGGCCGTTPEHIRALKDQLKGKEPIKRQTSNNHYV
RSKRLESKDHPVSNQKVPSVIVELDPPKSLSKLDIFVDGAKALTEAGADTITLADNSLAT
SRVDNVASATLIKQRTSASPLVHIACRDRNLIGMQSHLLGLHALGITDVLAITGDPTKVG
DFPGASSVYDLTSFDLISMLKEMNEGFSHSGRSLGVKTNFRVGTAFNPNVSSMEKAVKRL
DKKIKLGADFVMTQPVYDVDTLYALKKATAHINVPIYVGIMPLINSRNAEFLHNEVPGIT
LTKQVRERMQSCGQDVQRGEEEGLQIAKELQQHSLSLFERVYLVTPFLRYHITASLVQDA
KAQLSKQQLNTLH
>A0A7V8Y013|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MPGRLAKAIRQRSFAVTAEIGPPRGADTEPVRRAAKLLRDWVDAVNITDNQNAHVRLSSL
AGSIVALQAGVEPVMQLTCRDRNRIALQSDLLSAGALGVPNVLLLAGDHPRHGDHADAAP
VFDLDSAQLISAARQMRDDGRLLSGRELAPAPRWLIGAVDDPVGSPERLAGKVKAGAEFV
QTQFVVDVPAFEDWMSRVRDAGLHEQVAVLAGVGPIRSARALEFLRTELPGVQVPDDVVS
RLLGVPGDRTAEEGMTLCVETVQRLREIPGVAGVHVMSVGHEQGVPEILERAGVGRAQPG
>A0A497IKK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon|TrEMBL
MDFKRKIETGKFVVTTEVAPPRGTDTTLLIEEADLLSGCVDALNVSDNQRSIMRMSPLGV
AHVLQEQGHEVILHTTCRDRNRLALQSDLLGAWNLGVRNILAMTGDHPLLGDTMGTKPVY
DLDSTQLLQAIQNLNRGHDIMNRRLDGGTGFMAGAVVRPDPNDKMQLLRLKRKVSCGARF
IQTQPVYNTEEFKEFIEKVSHLNTHIIAGILPIFSLKTVKFINDKLPGIIIPQEVVERIK
NSTDPAEEGIELAAETIKKLQDVAGGVHIMPIITHQHTEAILKRAGMLH
>A0A7V1FWA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MIKKITDIFKEKEKTFSFEFFPPKTPKGIENLYRTVEKLNELGPDFASVTYGAGGSTRGA
TMEICAEIQKRFDLTVMHHLTCVGHSQGELKDIIDRIRTNNIKNILALRGDPPKGADKWD
PGPDSFEFCYQLNDFIRDNYGDFFSIGVAGFPEGHVQCPDKDTDTKYLKIKIEHGGEFVI
TQLFFDNSIYSEYLDRLEKTEIKVRVIPGILPITSYDGLLKFCDICGTTVTREVHDIFSP
ISNNEEAVRAAGIEFAVKQCRDLLDRGAPGIHFFTLNKTEPTSEIWRRLGL
>A0A7E4VGY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panagrellus redivivus|TrEMBL
MASVQPQTTDTLEPPTNGVNGATTNGTTNGFNRNLSTNSLKKLNSPIPYCGSTNDLPAYA
RSNSTLSRHSPDSAASVKASGDNLRECTEYVPLHKRIEKRISSGTPFFSLEFFPPKTANG
VANFLTRIDRYRDGGPMFLDITWHLGSDPANIEKETSSSSIAAACLAYCRVDTMLHMTCA
QYPKEQTLKHLQLAQNLGIRNLLALRGDLPINDSDPSIYPYRALDMIRWVRTHFGNYFTV
CASGYPKGHPEAPSYAADIAYLKMKVDAGADFIITQLFFEAETFETFVADCRAAGITVPI
IPGIMPIASYDSIRRVAELSKLTIPKHIMDTLESIRHDDEAVTKYGIHLAVEMCRRLLDS
GVAPSLHMYTMNREHSCREVLQALGLWQHESIRSLPWLPHGGHHPLRCREDVRPIYWCAR
PKSYIFRTKDWDEYPNGRWGNSSSPAFNDLQEYYMFYLKGLPNKEAMLQMYSRELNGIED
VCRVFVKFLTQEPNEEGVKISKLPWNEQEFETSAETELIKDQLVWCNENAIFTINSQPSV
NSAPSSDPLVGWGKPGGYCYQKAYLEFFISKARAIKLKAVLEQYPQVNYHVINKDASIDW
SNSDPTMPIAVTWGVFPGCEIAQPTVVDPLSFRVWKDEAYDAWLNIWAALYPEESKSRKL
LQDIHDDFCLVTLVDNDFVKPSVLFEILEQVISDENEAAVTFAASG
>A0A7X0LMG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces candidus|TrEMBL
MALGTASTRTDRAVTVRELLETGKTSFSFEFSARRTPKGEQNLWNALRRVEAVAPSFVSV
TYGAGGSTREGTVKATQKIASDSTLTPVAHLTAVDHSVAQLRNMIGQFANAGIRNILAVR
GDPPGDPMGEWVRHPEGVTYASELVRLIKESGDFCVGVAAFPEMHPRSESWDSDIRYFVE
KCRAGADYAITQMFFDPESYLRMRDRVQAAGCDTPIIPEVMPVTLVKQLDRLPQLSNAHF
PDAVRERMLAVQDDPAAVRSIGIEFATEFCATLLAEGVPGMHFITLNNSTATLEIYENLG
LHDQSSRPAQS
>A0A497IUT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon|TrEMBL
MAKERKAFSNLMKAIERGEFVYTGELEPHRSIDLSDVKDWATTLKNTGKIIAANVTDNPR
SDSAISSLVAAYIVQRDTGLETVYQLRTADRNRLALLSDILGAAALGLRNILALTGDHTK
IGTTPAAKPVFDFDSAHLVALIHNLVYEGKDLDGNEVHGPKPEINVGVAGNPNMDPLEAE
VLKLERKAEVGADFVQTQVIFDVEVARRFLKAVEHIGIPVLIGIFPPRSYGQASFFDKYV
PGVTVPEEFLEAFKKFKEIEDKERRKEKINEYNVEYFVNFIKEVKKEKACAGIHIMAVGY
PDVIGPIIEGVEK
>A0A0Q5CZK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. Leaf126|TrEMBL
MANHNFSIEFFPPKTAEGAEKLRVTRAKLSELKPRYFSVTFGAGGSTQRGTLDTVVEILA
AGEDAAPHLSCVGGSRESIRAILAEFRSHNIRRIVALRGDLPSGYGAAGEFRYASELVEF
IRQETGDWFHIEVAAYPEVHPQARSPQDDLLAFERKIKAGANAAITQYFYNADAYFHFVD
QARKLGIDVPIVPGIMPILNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VAQLGQRLLAGGAPGLHFYSMNQAAATTALWQRLV
>A0A1G7E5P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium brasilense|TrEMBL
MTETISSVHNAPRAPKAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTITRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAGIKRRHADIEISVSAYPEKHPEAKDFDADIDTLRAKVDAGA
TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A4U0VTK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodotorula sp. CCFEE 5036|TrEMBL
MTSTPELRSTFVSQKVTDKIAALPDNQPYYTFECFPPKTESGLVNLIDRIDRMSALNPLW
MHVTWGAGGSTQERSLELAGASQGMGLETCLHLTCTNLEQGVLEKTLERAKAAGIVNLLA
LRGDPPRGEEYWTAASDDFQHATDLVRFVRAKYGDTFAIGVAGYPEGHADSPDKQADIDY
LFEKQEAGADFVITQLFYDVDVFLQWYKRCRERGITIPIIPGIMPIQNYLSFRRMTNLCG
TYIPPNILADLERIQHDDAAVKTYGVELSVKMMRQLFENGIRGFHLCTLNLEKSVTRVLE
ALKWVEPAETRVRTSRQRTLAPNGGPLPKVVNSLRPAPAAGASVAGPDIARKDSPASWDE
FPNGRFGDARSPAYGEMDGYGVSLKLPPAEALRQWGQPRQLADVSRVFSSYLRGELPSNP
WSEEPLRAETDMIAAHLIEMNDKRHWWTVGSQPAVDGAPSADAVHGFGPKGGYVYQKAFV
EFFLTKEELDELERVSAREERERREKGEGDDGLVKWYAGNRAGDFRSNMGHGDVNAVTWG
VFGAKEIVTTTLIEEMSFRAWCEEAFALWNEWSLLYPAKSEARTFLRSLADSRWLVSVVH
HDYKDRDALWQWLMRLQPAASEGVDAEGR
>A0A1M3L7F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dysgonomonas sp. 37-18|TrEMBL
MTITELINKSDKTAFSFEILPPLKGNNVEKVYNIIDKLIEFDPQYINITTHHSEYLDQQM
PDGTVKRVNIRKRPGSVAIAASIQHKYNVTAVPHMICKGFSQEETEYALIDLNFLHVQNL
LLLRGDTKRLAPEQIYPNRNEYATDLQLQVNNFNEGIAADGSLFEKNATPFSYGMACYPE
VHEDAVSAESDIFYMKQKADNGAEYFVTQMFFDNQKYFSFVEKCREAGITQPIIPGVKPI
VLMSQLEVLPRIFRSSIPEELAVELRKCKTDDDAKEVGIEWGIKQSKELIEYGVPSIHFY
SLLATESVRRIAKEIY
>A0A1M7ZVB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium cucumis|TrEMBL
MKVTEHIQNANGKPLFSFEILPPLKGQNIQSIFDGIDPLMEFNPPFIDVTYHREEYEFKE
LENGLLQKKVVKKRPGTVGICAGIQNKYQVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSETYFKPEREGHAYASELVAQIYNLNNGIYLDEDLQNSTKTDFCIGVAGY
PEKHMEAPSMDSDIHFLKQKIKNGADYIITQMFFDNQKFFDFVNKCRTAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNDVVKQIGIEWCIEQSKGLVQAGIPVLH
YYSMGKAENIKAIAKEIF
>A0A7Y6FF12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CAI-24|TrEMBL
MALGTASTRTDHARTVRDMLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHRQS
>A0A812YJH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiodinium sp. KB8|TrEMBL
RAATAQEYFAAIAERWDEERSLHAPDDVVEAAIVEALAERPYHSVLDMGTGTGRMLQLLI
GDRLDVRAIGLDNSHSMLGVARANLERAEVHGVDLRQGDVYSPPVEPGFDLVVVHQARAV
HEARRLLNPGGRLLIVDFAPHALEFLRADHAHRRLGFRDDTIVGWLEQSGLRPDEPGRIE
PQHGATNPDDERLVVTLWLAHVFPPKTDAGLVQLAEAVAELEQLRPSFVSITYGAGGSSR
DRSFETISTVARHGSTMAAHLTCVGQSRADLDDVIDRYLSLGVSHVVALRGDPPEGIDAP
YAPHPDGYTSTAELVAAAKARGIEHISVSGYPEKHPQSPSDDHDMAILAEKAAAGAHRAI
TQMCFDTEATIRWIDRVRSAGIDIDIAPGIFPIHSFPAVARFAARCGASMPAEVAERFAG
LDDDPDTTAKVGAEFAAQQIARLREHGVRHVHLYTLNRAPLARAVTEQL
>A0A1R1Y2W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium culicis|TrEMBL
MLKLNPLFIDVTWRWGGKSKDLTQEICINSQDVYGMESNMHMTCVGTKIDQINAVLKTAK
KNNLMNILALRGDLPLSSNISSDSSKNQTLLNSSDTGFVSDSSCDSPVVLSNNSSSEDLV
SQTSLKLNSKMRLTNEFQSAEQLVKHIRNEFGDYFCISVAGYPEGCVDKSHVETDIHILK
RKVDAGADFVVSQLFYDIPVYMDWVKKCKDVGINVPIVPGIMPIQNYSGFEKMVKMCNIK
VPEEIWTSLNSCKGDDLAVKDFGIQYSIYMIKTLISNGIKGFHFYTLNLERSTQLVLEGL
ELVPLVKQPTLNNMSENNSSNLKYVTSGFFDKLCAFNRQTKDLPWQPSPIGKRATENVRP
IFWHNNTSSYIDRTKNWDEFPNGRWGDSRSPAFGELNYGQVWTYTKSQVINLWGTPTSVQ
DLVDLFTRYCQNKLSSLPWSDTELMLESNEIKPLLESLNKAGYLTINSQPSCNGVSSTNL
VHGWGPKNGFVYKKAYIEFFIEPTKCEKLIKFLSEFNAESIDSPMITYLAIKKNSQLKSN
WDIAKPNAVSWGVFPGCEIIQPTIVDADSFIAWKDEAFDYFQLWSNSYGHNQKYAETTSL
LSHISDTWYLMNLVDNNYTRSAEFMYNMLLSIGE
>A0A6L9SUH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium platyrrhinorum|TrEMBL
MHQPMFSLEVFPPKRDAPVGTIYDTLDGLQGMHPDFISVTYGHGTHADRTATARIANTIR
KEYRIPTVAHLTALYSDEAKVDEALEMFEHAGVDAVLALRGDYIEGETPVGVFERAIDLV
RYIRARKPALKVFGACYPEGHYQATSLDEDIEHLKEKVDAGATHLISQLFYDNEDFYRFL
DKARAAGIDVPIEAGIMPINGAKSLRSMAAKNNTVVPPAVEALLDRWGDDVPTLREAGIN
YASAQITDLVAHGVDGVHLYTMNRPATTRRIWRNVRPLFAKTGE
>A0A5P9F841|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. THAF37|TrEMBL
MATPNVSFEVFPPRTVDAAFKLWDSAQALAPLAPRFFSVTYGAGGTTRDLTHDAAHVLRR
TSGLPVAAHLTCVGASRAETMEVADSFAKIGVTDIVALRGDPADGADHFTPHPDGFSDSC
ELITALAETGKFNIRVGAYPDPHPESASPEANIEWLKRKFDAGADEAITQFFFEAETFLR
FRDACAKAGIDKPITPGILPIVNWKSARNFANKCGTPIPAWVDDAFSKAERDDRSALLAT
SLCTEMCSELVDEGVENLHFYTLNRAELTRDVCRALGVTPQVTLEDVA
>A0A3A9VEB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimarina sp. AD10|TrEMBL
MKVTEHIEKAKGKTLFSFELIPPQKGRSIQELYDNIDPLMEFNPPFIDVTTSREEFIYID
REGLLDKKLTRMRPGTLGICASITHKYNVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFIPTKGGHKYANELVTQISNMNKGQYLHEVIETNNKSNFCVGVAGYP
EKHMEAPSMDSDIRRLKEKVDAGADYVVTQMFFDNKKYFSFVEKARAAGINIPIIPGIKP
AAVKRHLQLLPQVFKLDMPDDLVRAIEGCKNNAEVREVGIEFAIQQSKELMDFGVPVLHY
YSMGKSDNIKKIASAIF
>A0A067M6N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryobasidium botryosum FD-172 SS1|TrEMBL
MKFTDKISQHSSKPFFSFEFFPPRTDQGFSNLLARIKGLSALEPLAISVTWGAGGTTKQR
SVELAGIVQSQYGVDTVLHLTCTNMERGMVDDVLRAAKKLGIQNIFALRGGMYPPHGSDH
WIPADPRFVHAADLVAYIRSIPEYADYFCIGVAGYPEGHTEAEPGDDQIGRLKAKVDAGA
DYVVTQLFYDVNNFFVWLKEVRRRGISVPIIPGVMPIQTYASFIRLNKLCGTRVPPYVSS
DLETIRHDDQKVKDYGVHLAMSIIRRLTANGEVCGIHLCTFNLEKSVRRVLGGLGWTNDA
PPQTNDQAHRHLPPDVLVSAHEVARAMSTTPSQEPDPFSVQSTATASTAHKLTPGWDDFP
NGRFGDPTSPAYGAYDMWDCGINLNEGIAQWGNPKSTTDLTSFFLSYLNSAISTTPFSPE
PLNVETSTILPHLIRLTSGGLWTVGSQPAVDAAPSSDGVFGWGPRGGYVFQKSFVEFFCD
RRTVEWIKERVNTHGKGLVSFYAGDGQNDFFSNAEEGRNAVTWGVFPDQEIVQSTIIERD
SFAAWMEEAFGIWYQWALFYPPDSAERELLEKASEKLWLVSIIHHDYKNPESLWDFLFEG
EGLPLH
>U7GTU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. EN3|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTREEIGELLDVYKENGINRIVALRGDMPSGMGASGELRYAN
ELVEFIRQHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEQMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTDMCEKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A3Q9FNF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flammeovirga pectinis|TrEMBL
MKVIDRLNLAAEEKKTLFSFELLPPVRGKSIQSLFDAIDPLMEFKPAFVDVTYHREEYVY
KELQNGLFEKSIQRHRPGTVAVCAAIMHKYNVDTVPHIICGGFSKEETENILIELNFLGI
ENILALRGDAAKGEASFTPHPEGYAYASELVEQVTKMNEGEFKYADETGFKGGFSIGVAA
YPEKHMDASNLDSDIDFLKKKVDLGADYIVTQMFFDNQKYFDFVERCRTAGITVPIIPGI
KPLTTKKQLTLLPSIFKLDFPQELFTEAQKCKNNKEVRELGIEWGIQQSKELIKYGVPGM
HFYSMGRSTSVKDIAEAIF
>A0A417SXL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. OM04-5BH|TrEMBL
MKIIDIINQDRPTLSFEVFPPKKDTDFADVEAAACSIAAYKPDYMSVTYGAGGSTKGHTI
RLAKEIQEKYNVPTIAHLTCVCADKETIRKALTEMKDAGIENILALRGDVPKNYEGEVFT
DFVHASELVRLIKETGDFCVGGACYPEVHPDSANKKADIEGLKKKVEAGCEYLTTQMFFD
NTIFFNFMYRLRTAGVMVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKSIVDAFGDTEA
AMRQAGIAYATDQIIDLMANGVKHVHVYSMNKPDVAYGIQKNLSEILKA
>A0A418PMR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus lacus|TrEMBL
MKITEHLKNAKSTLFSFEILPPLKGQSLKELLEGISPLMEFKPPFVDVTYHREEYIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFHVDAVPHLLCGGFSKEETENALIDLNFIGVDNV
LALRGDAPKTEGRFIPEPEGHSYASELVEQIVRMNNGRYLHEETENSFHTDFCVGVAGYP
EKHFEAPSMKFDLKYLKEKVDRGAEYIVTQMFFDNQKYFDYVAKVREAGITVPIIPGIKP
ITTIGQITMLPRTFFLDLPDALTDELEKCKTNADVKEVGIAWAIQQCKELIDAQVPSLHF
YTMSKADTTYKIAKEVF
>A0A1E8GGR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Floricoccus penangensis|TrEMBL
MNRIPFSLEIIAPPINTPYENFKDDLEDFIELNPSFIGVPTIDKVNMDKRSFELTRYIQN
DLSYPAMAHLPAKFMTEKHLEDTLNSFTNSGVREILVVGGEVRDEAKIYSDFPYANQLMA
FIREYSSDFHVTGACHPRGVEGDGDLAREMEDIKRKIDSGCQQLISQVFFDNEDFYRFKE
AYEKENFKIPVLAGVMPALSRGVINFMVSRNHTRLSPELEKVLEKYANDPASLRQAGLEH
SMEQIDKLLGCEIDGFHLYTMNDVLASKEIYMTFRN
>A0A6P9AAE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thrips palmi|TrEMBL
MSIRHCASSLAAEAAGCGAPNGFNAGLWRLSRSDAGDAAEAPRGGPRPTTPTAAALEAAR
RGIPDLIADNIKSETFFWSVELIPGTTPLLRSLLDESLQHLARHRPAFASVTWHVDHLAV
RGPDGPEQVEHPAMALSARLQDEHGIPALMHLAAGRMAKQHVHAVLQACLVAGVTNILAL
RGDYKVNADADFPHASDLVHFIRKNFGDKFKIGVAGYPSGHPDSKSREMNFVHLKEKVDA
GADFILTQMVSSAEEFNLFKQECDNREIRIPIIPGLFLIESYKMFEKLIRTCNILVSKEI
LDAMKQIKDENKEREYGKCLFLNLVVDLMKLSSCPGAHIFSMNRVTTATKVLDEARIFHD
AIE
>A0A847DI43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatiglans sp|TrEMBL
MSEFKSGSNLEKVLKAGHFAFTGECGPPKGANVEHLKEKIHHLKGMVDAVNVTDNPTAVV
RMSSWAASTIIIGEGMEPNFQMVCRDKNRLAMMSDILGAYAVGIRNILCLTGDHQSFGNH
PEAKNVYDLDSMQLISLTKKMRDEGKFLNDEVIDCAPRLFIGAAENPFADPFEYRPYRLA
NKINAGADFIQTQCIYNMEKFREFMKRVVDMGLHEKCYILAGVSPLKSVGMARYMAKSVP
GMDVPESLIERLKGAGPGRAADEGIKIVVEQIEEFKEMKGISGVHLMAIEWEHRVPEIAE
KAKVLPRPV
>A0A6G6NCX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas veronii|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPRG
>A0A6H9GHU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa NIES-3806|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILHQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFDCLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A388P7Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MAAGADFVTTQLFLDNEDYFRFVDRARAAGVTVPILPGIMPVLSLKQARNFCGFCKARIP
DALVRELEACGPDEEAQRKVGVSWAVRQAKGLVARGAPGYHVYILNKAESAVELFAALRA
>A0A1G1SQ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter coccineus|TrEMBL
MKVTDHLAQANGKTLFSFEVLPPKKGENIRTLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFTKEETENALIDLHFLGIDS
VLALRGDPIKSDGVFKPEPDGHAYACDLIGQLADLNKGEYLDEAQDDTWATDFCIGTAGY
PEKHFEAPNSGADIRYLKHKVDRGADYIVTQMFFDNEQFFDYERRCREAGITVPIIPGLK
PLTTKAQLTMLPRTFFLNLPEALVEAVSQCRDNEAARAVGIEWCLNQSRELMAHGVPCLH
YYSMGKAESIRKVAKELF
>A0A2P5N7A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas sp|TrEMBL
MESQKKFSRSFSFEFYPPKSEEGAASLIKVHNELAQLKPDYFSVTFGAGGSTRDKTFESV
VAIQQKGIPAAPHLSCVASSRDSIREILKNYQTQGVNKIVALRGDLPSGMMSLGELRHAN
ELVALIRQESGEYFQIHVAAYPEVHPQAANAAQDLKHFKLKVEAGADAAITQYFYSPEAY
FHFIEACEIASIDIPIVPGIMPITNYSQLFRFSEMCGADIPRWLRKRLEGFGDDRQSIQA
FGVDVVSELCQRLLDNGAPGLHFYTMNQSAPTLAIWKNLQL
>A0A2W1MI72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 57B-090624|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNTARQLASYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVKVPTAPHLSCVGDSKADLRSLLEQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VEFIRAETGDHFHIEVAAYPEVHPQARNFEDDLANFARKAKAGADSAITQYFFSADCYFY
FVDRVRKLGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDLESIQAFG
EQVVSEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1M6GVM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatibacillum alkenivorans DSM 16219|TrEMBL
MAEFKSNSKLERILRAGHFAFTGELGPPRGSSVEHVREKAKPLKGNVDLVNITDNQTAMV
RMSSWAASIIAKEEGLEPNYQMVCRDRNRLAMQGDILGAYAMGINNILCLSGDHMQFGDH
PGAKGVFDVDSTQLIHMVKKMRDEGTFQGGAEIEEPPKMFIGGAANPFAEPFEWRVHRLA
KKVAAGVDFIQTQCIFNMEKFRKWVAQANDMGLTEKVYILAGVTPMKSVGMAKYMKNRVP
GMDVPDEIIKRLQGAEKGKVAEEGIKIACEQIEEFKEMKGIAGVHLMAIEWEHKVPEIAE
RAKVLPRPVV
>A0A3D2KMX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MKRWPSLAKCNKMSFSIEFYPPKTTEDGEKLLAVARSLQGLPIEYISITCGAGGSSRGLT
LEYTRLLHQIGFQVMPHVTCVGQDEASIRDILSVYTEMGIDRVMLLRGDLRDNQPAGGDF
SRAIDLVRYTRNHFPSFKIGVAGYPEKHPEAPSLAVDIAHLKEKVDAGADFIITQLFFKN
ADYFAFVEHCRAAGIAIPIVPGLLPVLSLSQAERFCALSGSLLPEALRKALFECTNDKDA
MRAVGVQWTIQQLKELHSASPHFYVLNRAESLCAILKKVSLGLR
>A0A2H0NKA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellaceae bacterium CG11_big_fil_rev_8_21_14_0_20_60_62|TrEMBL
MGNTLIPISFEFYPPQTPEGAEKLTAVRQRLVALKPEFFSCTFGAGGSTQDRTLDTIKLI
HAESRNAAPHLSCVGATRENIGALLATYKSMGIKRIVALRGDLPSGMASIGEFHYANELV
AFIRSQTGEHFHIEVAAYPEFHPQANSAREDMLNFKRKINAGANSAITQYFYNADAYFRF
VDETRKLGVTTPIVPGIMPIVRFSQLARFSDTCGAEIPRWMRKTMEGYGDDAESIQNFGL
DVVTRLCEKLIAGGAPGLHFYTLNQATASMEILKRLGYRA
>A0A0C3GIM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piloderma croceum (strain F 1598)|TrEMBL
MRISKKIESSTKTDKIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSEMVKTCQSIIGIETCMHLTCTNMPKEKVDIALREAKQHGCRNILALRGDPPQGKDE
WEAVEGGFIHGIDLVRHIRNNYGDYFDIAVAGFPQHQLLPPDEFQQELVWLKEKVDEGVS
FIFTQMFYDVEVFISWVKAVRAAGITIPIVPGIAPIQTWNGFQRATSLAKTVIPKLFSDA
LEPYKNDDEKVRAIGTKLVADMCRRILEEDIGIRGFHFYTMNLEKATRMLLEELNLVPRV
ETIKPLPWRQSLTPNRRQENIRPIFWANRAKSYISRTQDWDSFPNGRFGDARSPAYGELD
GYGVSIKQSKEEGYKLWGHPTTFEEIKTLFSHFCTKQLAALPWSDQAPAKETSVISTQLA
KLNELGFLTINSQPAVNGVRSDDPIHGWGPSMGYVYQKAYLEFFVKPDLLSRLITHIERD
SDITYYVLNKNGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAYELGQQ
WAQIYDTNSPSRTLISNLMETSCLVNVVHNNFQDPEAIFQPFFKAGAEYAAAQGIAVNGH
AN
>R4VKY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spiribacter salinus M19-40|TrEMBL
MATTTGYEALATPRFELIPIRGMLDAAGHLPVGSVINVTCSPKHGLERTLDAAQALAGLG
HRPIPHIAARLVRDQAHLDRLLDQLAQAGMNEVFVVGGDAAKPAGDFDGAAPLLERMANA
PQRPSIIGLPAYPEGHAIISDDALATALAAKREFGDYLVTQICFDPARIRTWLGEIAAGG
THLPVYIGLPGVMDPKQLLSISLRIGIGTSLRVLRRNQGMTDQMLGGAYVPDALVKNLLP
LFEVTGEVPLAGFHLNTFNLVPPLLSWQARMLDELTVTEAG
>A0A832JV59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistales bacterium|TrEMBL
MREAFASKRLVFSFEVFPPKKDQPLEGLLEVARRLKELNPDFVSVTYGAGGSTRDRTMEI
AKHLWQELEITPLAHLTCIAHTRDEVDSILDELDVSGIRNVLALRGDRPQDGQIREDFRH
AVDLVRHIRARFGRGFFVAAAAYPEGHVESPSLKEDLFHLKAKVEAGVDLLITQLFFDNE
VFFAFMEKLELMGVSVPVSAGIMPVLNASQISRIVSLCGASIPSKLSRIMARYEHDPESL
KQAGIIYATEQILDLISWGVRGIHLYTMNRFEPAARIAENLRGLLEG
>A0A7V7BME2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp|TrEMBL
MGFLQDLQNRILIADGAMGTLLYSYGVDFCFEELNLLQPERITQIHETYIEAGAEVIQTN
TYGANFLKLSRYGLEEQVKEINAAAVQLARKAAKENTYVMGTFGGIRGIKKSAADMDEIK
KSFHEQLYTILTEGVDGILLETFYDLEEIKTVLEIARKETDLPIISQVSIHEVAVLQDGT
PLSAALKQLEELGADVVGLNCRLGPHHMIQALQEVPLPKKAFLSAYPNASLPDYEDGRLI
YESDDVYFGECAIHLRNEGVRLIGGCCGTTPKHIKAVSEKLKGLTPVTHKDVKIKNEKSM
ITIASKPSKPHLHEIVAKERSIIVELDTPKTLNTAKFLEGAKALKEVGIDALTMADNSLA
SPRISNLAMGSIVKNDIGLRPLVHITCRDRNLIGLQSHLMGLDALGIDQVLAVTGDPTKV
GDFPGATSVYDLSSFELINLIKQFNEGMTFSGKPLQKKTAFSVAAAFNPNVRHLDKAVKR
LEKKVEYGADYFISQPVFNEEQFLQIYEATKHIEKPIYIGIMPIVSTQNAEFLHNEVPGI
KLTDDIRARMARCGSDREKAEAEGIAIAKSLIDSAFDLFNGIYLITPFMRYEISVELVKY
IQIKKQKLTSFYAKKGR
>A0A7K2QRA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5471|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVQHPEGVLYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATQLCARLMAEGSPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A1L3I3B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter porticola|TrEMBL
MTTPDISFEFFPPQSLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRDLTREAVATLHK
SSGLNVAAHLTCVNATKSETMEIADQFAEAGVSEIVALRGDPPKGAAGFEPHPDGYANSV
ALIAALAERDQFSIRVGAYPDRHPEATSARADVDWLKRKLDAGADEALTQFFFEADTFFR
FRDDCAKAGIDTSRITPGILPIENWKGARNFAKRCGTTIPAWVEDAFEKAIRDGREDLLA
TAICTELCSDLMENGVEKLHFYTLNRPELTRDVCFALGITPKVALENVA
>A0A0H5QBG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis serogroup B|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A374UIW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. TF05-9AC|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRSHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKVGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A4Y8XVB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 4R-3d|TrEMBL
MALGTPRTRAGHAVPIRDLLAAGGRSYSFEFMPPRSAAAEAGLWTAIRRLEALSPAFVSV
TYGAGGSTRGRTIGVTGRIAQETTLTPVAHLTAVDHSVAELRNILGHYADQGVHDILALR
GDPPGDPLGPWTKHPQGLEYAAELVQLIKESGNFCVGVAAFPEMHPRSTDWDSDIRHFVD
KCRAGADYAITQMFFDVDDYLRFRDRVAAAGCTTPIIPEIMPVTTIRSLRRIPSLSTAVF
PAGLAERMLAAEDDPKAVRALGIDHATEMCRRLISEEAPGLHFMTMNFSKVTTEIYQNLG
LHH
>A0A1T2KW20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solemya velesiana gill symbiont|TrEMBL
MDSQKKFEKTFSFELFPPKTEAGMEKLQANVKELAAVNPLYFSVTYGAGGSTQERTFQSV
EWLVSQKLDTAPHLSCIGSSREEIIEILEHYKSQGIHRVVALRGDLPSGAGLGGIGDLNY
ANELVTLIRETFGDHFHIEVAAYPEFHPQAPSAEADILNFKRKVDAGANAAITQYFYNPD
AYYRFVDSCEKLGVDIPIVPGIMPITNYTNLIRFSDACGAEIPRWIRKRLEGYGDDIASI
KAFGIEVVSAMCDTLLRHDAPGLHFYTMNQSEPALKIWKNLGL
>A0A503W003|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-2-2|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKSDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTVGRILKETSLTPAAHMTCVDAPRPQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVDALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVA
GSAAA
>A0A3L8S2Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloebia gouldiae|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCHQTKDEITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIISQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVQGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLNSPTQQ
>A0A520EY57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp|TrEMBL
MTRTPSIVDRLRTEPEARIPFSVEFSPPRDEAAEARLWRAVREFEQLQPAFVSMTYGAGG
STRDRTVRVTGQI
>A0A1F9DXB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_19FT_COMBO_46_12|TrEMBL
MEQNRFKETLLERREFVYTLELVPGRGSRGKTQDEIIRVAEKAAKSRLIHALTITDNPGG
HPALSPDVIGLEISRFGIDPIIHFTCKDKNRNQIESVLYSLDRIGIRNLLAMSGDFPLYG
FEGEAKPVYDLDSVQLIRFINQMNEGLDIDGKAPGGGVRLPPTHFFKGSTISPFKKYEAE
VMAQYYKLYKKVKTGADFVITQLGYDARKFDELLRFMHHHGIRIPILGNVYVLNQRVAKV
MNQGKVPGCVVTDDLYRIYEEEAKSPDKGQAARLTRAAKLISILKEIGYDGVHIGGPNLS
YEDVEEVIEKSKDFSSRRESLVDEFSFPQADGFYLFEKNPKTGLNTDIPLKKKRKLRKPV
GYAIMRFLHHSAFTQEAPLFKPARWFYKKIDGTWFDGPMTELEYWIKFITSRCRRCGDCT
LLEVAFLCPQSQCPKYLFNGQCGGSSEGWCEVFPGKKTCIYVRAFDRLKPYGEEESIKTG
YTPPRNWALDQTSSWANYFLGRDTMV
>A0A0H2XSP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cenocepacia (strain AU 1054)|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTNLCQRLIDAGVPGLHFYTLNLATATRTICERLAV
>A0A7V5YFY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Acetothermia bacterium|TrEMBL
MTSLQQALAKGEFAVTAEVAPPKGIDTSEMMENAEFLRGKVHAINVTDQQSSVMRLGSLA
SCRLLKESGFEPVFQLTTRDRNRIALQSDLLSAYALGIENVLCLTGDHVALGDHPQAKPV
FDLDSVSLLMAAKGLASGTDMAGESLEGIPTFHLGAVVTPGYEPMEIQLLKMERKIKAGA
QFFQTQAVYDPELFRRFMEGAKDLGVPVMLGLVLLKSAGMARYMNKNVAGVSVPDSIIDE
MKKTDDKVATSIKIAARIIRQTREMCQGVHLMTMGWERYVLDILTEAGVTI
>A0A6A2XJ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hibiscus syriacus|TrEMBL
MASPAPEETQSPPHGQDKFVQVEGSFACALDLITVALEPIKDNDEAIKAYGIHLGIEMCG
KILANGVKTLHLYTLNMEQDHILKANVERKEASALPIQVERREASALPIQVERREASTLP
IQVERKETSALPIQVEQKDVDYTCTPEEVQKHFQSCGTANRVTILTDKFGQPKRFAYVEF
VETDAAQNALLLNESELHGRQLKVSTKRTNVPGMKQYRGRQANPYFLSRRPFMQGPVFYP
PYSYRCMEVKGFGFSAMLSVSFGFPNMISAMPTGYSHCLYFLELLQNENFPNAMAHPANK
EVAHRQQFFFWKNYRNNRFKFILPRPPPDKSTTTTLPFNNNVSQCHIHLLTKSCQAAVHI
ISPGSNMRRQSQQVMNITTETESSPARKFEDERWKNGTWDLNMFVRNDRIDCDGVIVAEA
ERGTCLEMKLVLTKNQESRLQNGVGVGVIMSRKSEDFDNMRKLADEVTC
>A0A495QVY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula quadrata|TrEMBL
MALGTRTVSDSQGVRTLLTSARFELMPFESFDEEISHLPDNATIAITTSPQLGIEKTVEK
TAEAAEMGYDVVPHIAARYVEDREQLESIAERLEQAGITDIFVPGGDREEPAGEYESALD
MLEALKETEYSFEEVGITGYPEGHDFIDDETLAESMAQKAPYATYIVTQLCYDPDAVLEW
VEDIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVEDDEYNIRGVHIYTFNQTPDTEKWRHKRLDS
>A0A7C5T004|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Acetothermia bacterium|TrEMBL
MKFRERLAQGEFVITCEAAPPKGTDTKEALENVRRLAPLVHAFNVTDLQSSVVRMSSWAL
CALIRREGFEPILQVTCRDRNRLALQADLLGAWALGIENVLALTGDYPTLGDHPQAKPVF
DLDSVQLIALIQALNSGKDLVGNELSGKTDFFVGAVINPAADPLEPHLLRLRLKVELGAR
FVQTQAVFDPEAFVRFAQKAEPLGIPILDGIIPLKSAKMARFMNENIAGIRVPEELIREM
EAAKTAEDRKKRSVEICVRIIREVRPYCQGIHIMPMGWEELVPEILELAGLP
>A0A7X7JGQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp|TrEMBL
MTFDSVRGRASEGWATRTPSIVDRIGVSNDGRVPFSVEFSPPRDEMAEARLWRAVRVFER
LGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWQKHPEGVEYAEELVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGSKPIIPEIMPVTSLRSV
RRMLELSGSSLPAHLERKFDLAAGDGPEENRAAVREIGIDLATEMSERLIAEGAPALHFI
TLNYARATSEVLERLGDKVGSGAAEPSASSVDAARAGSASVS
>D7CTS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Truepera radiovictrix (strain DSM 17093 / CIP 108686 / LMG 22925 / RQ-24)|TrEMBL
MSYLQPDYTPRVSIELVARSLEGLAAELETIRARFPFVDTVNIPDLTRFALRSTDACAAA
QRCVRRAIPHLRAVATDLKDLRPLLRHLDEAELHEVLVVAGDPPADMRYAVYPTSSVQLI
RAIKAALPHVTVYAALDPYRQSFVRERDYALEKLEAGASGLFTQPFFDLRLMHVYRELLP
GVTLYWGVTTVTTARSLGYWQTRNRAIFPADFAPTLAWSRDFAARALEFARQTRSNLYFM
PIKSRLEDFLGGVLTPQRLGVGAV
>A0A2A2DRP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. PICF141|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARHLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A418QPP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter rubripertinctus|TrEMBL
MKVTDHLTRAEGKTLFSFEVLPPKKGENIESLFCNIEPLLEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFTKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFVPEPDGHSYACDLIGQVADLNKGEYLDQEQDDISATDFCIGTAGY
PEKHFEAPNYGADLRYLKHKVDRGAEYIVTQMFFDNEQFFAFERRCREAGITVPIIPGLK
PLTTKSQLTMLPSAFYLNLPEELADAVHLAPDNAAARQIGLEWCISQSRELMAHGVPCLH
YYSMGKSETIRQVAAALF
>A0A504LJ12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. CU2|TrEMBL
MTGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A1Q9GUJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium proteolyticum|TrEMBL
MGYSHASHLDSLNQNIADLNGDINVSFEFFPPSSEQMEQTLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKEQTGLVAAPHLTCIDASRDELRTIARDYWNNGIRDIVALRGD
LPEKGVKPDMYAVDLVELLRKEADFDISVAAYPEVHPEAKSAQSDLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNMVQAKRFALANNVKIPGWLEKQYQ
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAEAGVQV
>A0A7W0G9G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSSRFLERLRSGPPLVADGGMGTLLSGAVPRLRCPEEANLRAPESVVALHASFIRAGADL
IETNTFGANRRKLATRFLENELERINSTGVRLAREAREMCGGEVFIAGAIGPLGELEQFD
AGETAPLVAEQAQILEGRGVDLLLLETFYDLDELVTAVEAVRSVSRLPVVALMTFDADGQ
TLGGVDASEAAERLDGLELAAIGANHSAGPAAALNAIAQMRGDGRVLAALPNVGLASLAG
SRVIFPHATPDYFAEFAAQARRLGAGLIGGCCGTTPAQIAAIRSAVDEDRAPSAPFVVRE
RELVAASEDTAIEETKLARMLREQEFVVSVQLDPPLGGSNAALLETARVLEESGKAHFLD
VNDNPRARARMSGVMASVAIERACGIETIPHLTPRDMTVAGLESLLLGTHAEGVRNILAV
TGDPPEEGDYPGARGVYEVEAIGLTRLIANLNRGEDNHGRTIDAPTAFFTGVAVNPSADD
LAVELDRFERKLEAGAQFAMTQVLFDLQYLDAFLAHFGGRPPIPLLVGIWPLRSHELAVR
VHNEVPGMVVPDGVQQRLLDAGGAAAEVGAELARELMAEAREKAAGVYLVAPFRQPLGIL
EIL
>A0A6J4IXB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Actinomycetospora sp|TrEMBL
MATVTERIQRGVPTFSVEFFPPKNDEGEATLWRTIRQLEPLDPAFVSVTYGAGGSSRDRT
IRTTGRIATDTTLTAMAHLTAVDASLEDLRQVIGSYLAAGISNVLAIRGDPPGDKDADWV
PHPAGLSYTEELVHMVRRLGDFCVGVAAFPYQHPRSIDEDTDTRYFIQKVKAGAEFAITQ
MFYDADQFLRMRDRIAAAGCDIPIMPGLMPLTTPKSSERGADFSGAPLPAAMLEKLEPLA
EDATGYREAGIDLCVELSQRMFDEGVENIHYISMNRSPAVVDVVQRLGLAPRPES
>A0A7U9DNA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lividans 1326|TrEMBL
MRDILATGKTSYSFVFSAPKTPKGEKNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVRE
TQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPNADWIAHP
EGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTNFVDKCRAGADYAITQMFF
QPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASFPAELKERILTAKDDP
AAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPRA
>A0A7W0QMI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRRTGVLTELLARPRYEVIPLAGAEEAVLEHVPTEVNVTVTTSPRKGLEPTLELVEKVAA
HGYTVVPHLAARHIRDMGHLAELVERLRATGANDVLVLAGDAEQPAGEFDGSLPLLRALA
ELGQPFHDVGITGYPESHAFISDDATIKSMFAKEEFATYIVSQICFDPQVTAAWVAAVWK
RGTRLPIHIGLPGPVPRSKLLRVSARIGVGDSLRFLRTHRGWLGSTFRGAFDPGPLVEGL
EKSLDHPRPNVAGFHLFTFNDLETTERWRQEQLQRLRSPVPADADALR
>A0A136QIX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas monteilii|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSTERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEDEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMNRQAAPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPMWATRLGAQVLHKVEHAVKHPLVGCETCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTALLTERLIPCIELETRHRSSWPQWFQAQTP
RQLSPQPAPRTQPES
>A0A839PDF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. RMAD-H1|TrEMBL
MSVFGLSRRPDIGQTTRVSFEFFPPKTEEMEKRLWETVTRLAPLKPEFVSVTYGAGGSTR
ERTARTVARILKETDVTPAAHLTCVDATKEEVDTVIREFAGLGIKRFVALRGDPAGGVGE
QYRPTPGGYFNAAELVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPILPGVLPIHNFSQVTNFCSRAGTHIPAWLAERFD
GLENDPQTHMLVAAAVAAEQVLDLIERGVQDFHFYTMNRADLAFAICHLIGIRPQKQGSE
KEPTRAVKPDLAGAAA
>A0A7K0YYT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MERMTVSVEFFPPKDDAGEARLWEASTALESISPDFISVTYGAGGSTRDRTVQITKEITK
RTGRSTVAHLTCVGSTKDELIEILGQYKSAGIKSILALRGDPVGGPAAKWVSKPGGFDHA
DQLVELAMGQGGFEVGVAAFPDGHPASNGNLAKDIDVLLSKEQLGATFATTQFFFESSKW
ETLVSELAKRGSVLPIIAGILPITNVKQLHRMAELGGTAIPVQVSKLFNEIADDPEAVKR
AGIELATNLCNELIALKVPGLHFYTMNSSPATLEICTNLGLTNRE
>A0A6I3H673|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MLNKQVRVSFEVYPPRDQNSGESLESSIIELAKMDPTFISVTFGAGGSSTKNSLEVLKYI
LQNTQAAALAHLTCVGHSFLETKALVNQFMDEGISDFLALRGDPQPGMPVEPKGELKTSS
ELVQLISQVHKDRGNSRSTLNVAVATFPNGHPDSDSIAQDIQALLAKQNAGADYAITQLF
FFASDYVAFVKLAREAGVTIPILPGIMPVTSMQRLNRVIELTGEKYPEALAKQLSVTSKE
EAKQAGIDWAANLVSELVEQGAPGVHLYAFNQHESVTQVLQRAGIR
>A0A538IS06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKRSEFADLVAEQPLLADGGTGTTLVARGVRPDACFDALNVAARDLVREVHESFVEAGAQ
VIETNTFGANRYKLAAHDFAFRVHEINVAGVARAREAGARYVAGSVGPLGVRLAPYGRVP
KDEAQEAFAEQIRGLVDGGADLLILETHSDVAELEQAVLAARAVTDLPVVASLTFTRDDR
TLLGESPEAAAARLAGLEVDMLGVNCSEGPEQVLRLIRVMKPHAGGIPLVAQPNAGGPQR
LGGRIMFSATPEYFGEYATAFVAAGVRLVGGCCGTQPPHIRAMAGALAAPARPLDIEVEE
HSDEPAELRAPAQPTGLAQSLASAKVTIAVEMEPPRGFSAARLVAGADTLRAAGADVINV
SDMPTARMRMSAWAACHLVQQEAGIETVLHFPTRGRNLLRVQGDLLAAYALGIRNIFAVM
GDSTSIGDFPEATDLSDVTPSGLIALVKGSLNAGLDRAGSSIGDPTSFVVACALNVTASD
LEREARVLKRKIDAGADYAITQAIFDAERLDHFRALYEERHGPLELPILGGVLPIASRRH
AEFLHNEVPGIDIPDAIRKRVGKAADERAEGLAVAVDLCEELRARVAGLYLIPPFRRYDH
AAELIELVRS
>A0A022J3Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 1564232|TrEMBL
MSHLSPCFQQNQFFVLVEYLTSLHEIYPVRREFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEFFLEQAKSANVQNLLLLTGDKLKEHHNGRDGQLRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHVGFSGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
SGKEFSPEITYFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGLGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVAQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A7X9KI45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
DLVSWVRRQTSISPMAHLTCAGHTRDDIRAILTDYRAEGVENILALGGDLPADGETESDY
LFSMELVDDVREFGGFSVGVAAHPELHPRSPDRGTDRQHLANKLAAADFAITQFFFDIEH
YLVMIDELASLGVTKPVLPGIMPISNLGQITRMAHMSGAEVPGWVIEAMEKAGDNLDAAE
RIGVDLATELCARLIDEGAPGLHFYALNRSWATREIFRNLGLRPAL
>A0A8F7Y527|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio neptunius|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDASREELARIADDYWANGIHSIVALRGD
IPPGGGKPEMYASDLVKLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPVV
>A0A7K1BPB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
NVADFAITQFFFEADPYLRLVDGLSAFGCDKPVLPGIMPVTNAAQVVRFAELAGAAFPPH
LAARFDAIADDPDAVRALGVELASELCQRLLDEGAPGLHFYTLNRSTATREIAANLGLGD
ASSTGA
>A0A7V0V651|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGFKEALAKGEFVITAEVGPPKGTDISEMVHHVEALKGKVTALNVTDNQSAVMRISTLAV
SKILLDLGVEPIYQMTCRDRNRLGLQSDLLGAAVLGIKNVLALTGDHTTLGDHKSAKPVF
DLESVQLLQVIQGLNEGHDMAGNALKGKTDFFAGAIVTPEANPFEPQFAKFEKKIEAGAK
FFQTQAVYDIKKFHAFMDRASKYNVPILAGILLLKSAGMARFLNKFVAGISVPDELIQEL
ANSEKPLAKGVEIAGRQIRELRNVCAGVHIMAIGAEDKVPDILAAAGI
>A0A7K0KR07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPPASGFGSSVSTISELLSLGRHSFSFEFFPPKTDDGERLLWQAIRELEPLRPTFVSVTF
GAGGSTRDRTVRVTRRILEETTLVPVAHLTCVAASIAELRSVIGEYADAGLRNVLALRGD
PPGGPGTPWVQHEGGLEHADELVALVRSLGDFCVGVAAFPEGHPESTSRDDDARVLLRKQ
EAGAEFAITQFFFRADDYFDLVERARAAGCTIPIIPGLMPVTNLSQIERFSVLSGAAFPA
ELATRFRALGDDAAAVHALGVEVASEMAAEVLAGGAPGLHFYTLNRSTSTREIYTGLGLS
AFA
>A0A3S4U129|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachnia propionica|TrEMBL
MSPTVAELLRDAASPTLSFEFFPPRTPEEQPRFEATVAKLGRFHPAFLSVTYGASGSTRD
RTVAATAALGSAQHATVVGHLTCVSQSTDDLLRTLDAFADAGVSDILAIRGDMPGGPQQP
WERHPDGLGNATELVRLIKAHGDFCVGVAAFPNVHQPDNDPELDARIVAEKAAAGADYAI
TQLFFESHRYVELVNRVRERGSQIPIIPGIAPLTVITQIERFASLADCPLPEDFVAALRA
ARNPAEVRSIGLSRAVNLCRELLAAGAPGLQFFTQNRWKATSEVLDAIGWGDRVS
>F3B1E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae oral taxon 107 str. F0167|TrEMBL
MENIREYLKNNVLLFDGAMGTYYDELTDDGIGCELANIKNSELIRGIHKEYIEAGAKAIL
TNTFATGIDAFLGDRDLQKKVINAGIDIAIEAAKEEAYVFADMGSLSADSNNAAFEEYKI
IADIFLEKGIKNFFFETRNSTIGLKSIGEYIKEKSPDSFIIVSFAVMPDGYSSEGYYYKT
MFKEICESGFFDAVGLNCMTGANHMAKLLKDVNTEGLYLVAMPNAGYPIVRDNRIYYGSL
ANYFATQIEDILDMGVNIVGGCCGTTPKHIELLKKSMSGKLIKPRRAIKQEKGITQNIRL
NRFKNKLELGQKAIAVELDSPIDTNVAKFMENTKKLKLAGADIVTIADNPIARARMDSCL
LACKVRNELDFDVLPHMTCRDRNVNAAKGLLLGASAFGVDNVLVITGDPIPNAQRDEIRS
VFEFNSVKFANFIKSLNDEVFESPMNICAALNVNSRNFSAELKKAKRKQENGVEVLFTQP
VLTKRAVENLKTARENLDIKIMGGIIPIVSERNARYMQSEVNGIYITDDIVEKYIGKERE
EAEEIALSMSKEIANEIYDLVDGYYLITVLNRVSLMEKLIKTVKEVCENR
>A0A7W1KV77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
FFVGAAVAPGASNLGREVRLLQRKVRAGAAFLLSQPLYDMAPLRALRAAYEREAGRPLEV
PIMAGLLPLASARHAAFLHNEVPGVEIPDAVRSRMGSVGVDAWHTGREIAIELVDELKAE
GVAGIYVMPQFDRYDRAAELVEAARS
>A0A6I3H7W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
NPDDVRKLGVEIATELSQKLLDAGAPGLHFYTMNTSTATREIFENLKKR
>A0A0E2GL80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter nosocomialis NIPH 386|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRLEFAGYPAAITLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KKAKSFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELNVLEELWNSLWQVT
TGKEFSPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGFGRFIFKAFFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEVLKEKLIPTVPLETRGTSSWKNWYLGAEA
>A0A836SCS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichaceae bacterium|TrEMBL
ILKLLQEYQAHGIRRIVALRGDQPSGWAGPLGKFRYANELVEFIRAETGSHFHIEVAAYP
ECHPQAQSAKADLDFFKQKVQAGANSAITQYFYNADAYFRFIDGCTQRGIDIPVVPGIMP
ISHFEQLARFSDTCGAEIPRWLRGNLKDLEADKAALQAFGVDVVTTLCERLLAGGAPGLH
FYTLNQAKLTLEIAKRLDLF
>A0A6I3CM54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MERMTVSVEFFPPKDDAGEARLWEASSALESISPDFISVTYGAGGSTRDRTIQITKEITK
RTGRSTVAHLTCVGSTKDELIQILNQYKNAGIKTILALRGDPVGGPTANWVTTPGGFDYS
EQLVELAISQGGFEVGVAAFPDGHPASGGNITKDIDVLIRKEQLGATFATTQFFFESSKW
QNLVTKLEARGSKLPVIAGILPITNVKQLQRMAELNGTPIPETISKAFTGIADDPESVRK
VGIELATKFCEELIALKVPGLHFYTMNNSLATLEICNNLGLTNRG
>A0A2W4JNP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTIRELLAVKRPTLSYELFPPRTPASEATLAQTMDLLAATGPDFMSITYGASGTTRTTSR
EVVHRLAVAHTIPPLAHLTCVDQSRAELIEVIESYLAEGVRDFLALRGDPPKGQTDWRPH
PEGLLYAYQLVALIREVARAHGVDNLSVGVTAFPAQHAQEQWRQISLDVLRAKQEAGADF
AITQVFYEVEHYRALVDDAAAEGIGLPIIPEIMPLVSATRSLRATQLTGVPTPAELHAQL
EAAESDDAARAVGVAHAARLSAQLVDAGAPGIHIITFNRHEAALALVTELGLTAS
>A0A538M0I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDQILADGRPAFSFEFFPPKTQAGERNLYAALSELRTLDPSFVSVTYGAGGSTREKTI
EIVKRIREEYGLEAMAHFTCVGATVPQLHATLDEMEQAGIDNVLALRGDPPAGQEHWTKT
EGGLEYSRELVELIGNGYPFAIGAACFPETHIHAESPKADLEHLAEKVAAGVDFLITQLF
FENDVYFAFVDRARAIGIEVPIIPGIMPITHAGQVERMASMCGASIPAGLHRELHAREEN
PEAVLDFGVAYATLQCAELLAGGAPGIHFYTLNRSPATRAIVSALKLSRPWKRVS
>A0A538MRJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSDRFEKRLERGPPVVTDGGMGVLVSSAVAGLRCPEEANIRAPESVVTLHTSFIAAGAEL
IETNTFGANRHKLRSQFLDNEVAAINEAGVKLAREAREISGRDVFVAGSIGPLGELGGLA
ADERGPVFAEQAALLEGRGVDLFMVETFFDLDELTTAIEAVQGVSGLPIVAMLTFDEDAE
TFGGVSARDAVERLTQYELAAVGANHGAGLHAALAALEAMGDGRPLAALPNVGLASLSGG
RVIYPHATPEYFAEFAAQARALGARVIGGCCGTTPTEIAAIARAVEEERQPTVPFAAAER
ELVVAAHERPEETELARRLHAGEWVTCVELDPPKGGSYESMLAVTRTLNGSGAVGFVDIN
DNPMARARANALMAAIAIERSCAIETIPHVTPRDTSVMGLQSQLLAAHAEGVRNVLAVTG
DPPHVGDYPGSRGVYEVDSIGLSQVVSRLNAGEDFNGKAIDAPTSFFLGVAVNPSADDLE
TELDRFHQKVEAGARFAMTQALFDLAYLDRFEQLLGGWPIPILVGIFMVRTHQLAVRLHN
EVPGIVVPEDVQNRLRDAGPRAAEVGLELARELYAEAREKAGGVYVIPPFKQPEAALELL
GS
>A0A0X8JXL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. oral taxon 431|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQDLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDLIPDVEPQKDFRYATD
LIEFIKEQAPHFEIIGACYPEGHPDSQNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQSLG
>A0A537WXD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGGRRGDQPRARRRRSHDRRDAPRQHGPGRRGAGLRAAVTRPPGRLAALLARGAFTVTGE
IVPPKGASGDPVSEHARGLVGYVDAVNLTDNPVASAHMSPLAGVIFVADAGIEPTVQLTA
RDRNRLGLTADLLGAWALGARNVFCLSGDPVQVGDHPDAVVVRDLTVGDVIGLARRMRDD
GTTLANTELADPPRFLIGVADVPFAEPYDPSRLESKLDAGADFVTTQIVYDADRLAAWAD
VMRPRGLFERAKVIIGVTPLRSAKQARFMDEKLPGVHVPSPTIAALEAAGEDAGAVGMDL
TVELVGAVQTIPNIAGIHLMAMGHDDVTRELIERTGLFPRPTV
>A0A4R4K1K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arundinibacter roseus|TrEMBL
MTKVTEHIAQAGDQTLFSIEIIPPLKGQNINQLLDSIEPLMEFKPPFVDVTYHREEVIDK
VHPDGKIQRIPVRKRPGTVGICARLMERFRVDAVPHVICGGFTKDETEDMLFDLHYLGID
NVLVLRGDPEKSAGVFKAKDGGHAYASDLISQVVAMNHGKLLHEETEASHTDFCIGVAGY
PEKHFEADTFDIDFGYLKKKVDAGADYIVTQMFFDNQKYFQFVERCRAAGITVPIIPGLK
PLSTRKQLSILPRIFHLEMPPELVQEAEKCASDADVRQVGIDWSIQQCKELIAFGVPVLH
FYTMGKSDNVYQIAKAVF
>A0A256X0L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. UW-LDO-01|TrEMBL
MSREPQRLIDVLNRGTFAVTVEYNPPKGTNISAVLENAKQLVGRVHGVNITDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMRLVQGLNNGKDMMGNKLDGSTAFTIGAAVTPEAELVGPVLAKFEVKV
KAGAQFFQTQAVYNPDVFASFMKQVQPFKVKVLAGILVLRNHKMAEFMNANIPGMSVPQE
MIDELKAAGDRSEDVGVDIAVRSIKAVRPHCDGVHLMAIKATHRLAEIITKAELG
>A0A2E5I0U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTLFSNAGRMDRSTAAPLRRRLLSAARFEVIPLNNLSSQLAHLPLGASVSVTASPNKSLE
DTWRLTSDLLSRGLRPVPHLAARMVESHQQLKRLVQELADLGLSELFLVGGDAPAPFGPY
EDSVEVLQAILELDHQLDHIGVTAYPDGHSFIESPVLSSSLRKKQQLLEEAGMQGHAATQ
MCFDSDAIREWLKRERREGLKLPIHLGIPGAVQRAKLLSVGARLGVGASLRYLQKNSGAI
GRILLPGGYNSNKLLSPLAGSLEELNVTGLHIFTFNQIEATVAWRDNAVATLKI
>A0A0S8B7D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium SG8_39|TrEMBL
MTAVTAAEQSATLMELAACGSLEMNADRAGDAGTIADLLPTGTKVYVNHLPRNALSETLK
SLDALRAAGLEPVPHVAARRVVSRAALKDFLQRAVRDAGVRKVLLIGGDDPQPSGPYRDS
LGPLSDGLIAECGIQEIGIAGYPEGHARIPRAALERAMDEKLALSAAQGLSPYVLTQFSF
APTRVIEYCAELAQRWPALSVYVGLAGPTEPVRLLRFAQRCGVSASLRALRAQGFGVARL
VTHTDPGDQLQAVARYCAPRRACNVVGVHVFSFGGVREAATWMNRAIGGGALSAAAG
>A0A537V7E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTRPPGRLATLLARGGFAVTGEIVPPKGASGDPVSEHARGLVGYVDAVNLTDNPVASAHM
SPLAGVRFVAEAGIEPTVQLTVRDRNRLGLTADLLGAWALGARNVFCLSGDPVHVGDHPD
AAVVGDLTVGEVIGLARRMRDDGTTLANTELADPPRYLIGVADVPFAEPYDPSRLESKLD
AGADFVTTQIVYDAERLAGWAEAMRPRGLFEQSKVIIGVTPLRNAKQARFMDEKLPGVRV
PSPTIAALEAAGEDAGAVGMDLTVQLVEAIRTIPV
>A0A2W4NMP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAIQQEVSGSGRRGSTLADLVRNMGYEVMPFKRTEQDVLTYVPKDVPLTVTVTVAKGIDT
TLDLAERLHKHGYTVAPHLPARQFVDAKHVEDVVARLKEAGIRRVFCIGGDAPTPAGEFT
ESYQLLKVLHELGNPFENIGIGGYPEGHALIPQHAIEEALRKKAPLADRILTQICFDATT
TATWAKRIAAEGVNLPIYVGMPGPVNRQKLIRISAGIGLGQSARFLQKQSNLLWRFLLPG
VYNPTKLLKRLAAASAKIGGNIRGLHIFTFNELEGTEKWRQKLLASVAGRDDRS
>A0A2A8HNE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. PC22D|TrEMBL
MTPPILNPAREEQMAHASPLFAAVPGDIAVSFEFFPPKTDKMHAQLWSAIETLAPLDPRF
VSVTYGAGGSTRERTHDTVARIARETNMAAAAHLTCVEATKEEVDAVADAYWQAGVRHIV
ALRGDPPEKGKPYSTHPGGYENAAALVEGLRKLHPFEISVAAYPECHPDSADPQTDIDNL
KRKMDAGANRAITQFFFEPDTFFRFRDDAARAGIDAEIVPGIMPVMSFGAVSRMSAMCGT
DVPSWMATLFEGLDDHPEARQLVSATIAAELCRRLYAGGVREFHFYTLNRAELAYAICHL
LGVRPKTDAAALQAAARETAI
>A0A0H4VDJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantiacibacter atlanticus|TrEMBL
MSAPLSAPAKIADCLDPEHEVRTARDTPLFSGLPGDIAVSFEFFPPKSEKMEEKLWEAVQ
QLAPLSPEFVSVTYGAGGSTRERTHNTVTRLIREAGIPAAAHLTCVDASRAETQKIAEAY
WEAGVRHIVALRGDAGEPGAPFIPHADGYANAAELVRGLKEVADFEISVAAYPETHPDAD
CPQADLDNLKRKIDAGASRGISQFFFAPETFFNFTEKCRAAGIDAPMVPGILPVTNVAQA
RKFAGQCGAVIPDWMDGLFEGLDERPGARQLVAATIAAELCRRLYAGGVRQFHFYTLNRA
ELAYAICHLLGRRPLEKSA
>A0A538ESP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDEIIASAEEPVFSFEFFPPKTPEGERTLRDTLGTLRGLQPDFVSVTYGAGGATRERT
VEITKWIKQELGIEAMAHLSCVGEPVDRLREMLDEIAGAGIDNVLALRGDPPRGEKEWTP
HPDGLRWSTELIALIAGGYEFCVGAASFPEVHPDAPDLAHDIRFLKEKLAAGASFLITQM
FFDNRYYFDFVASCREAGITAPIVPGVIPITNVAQLKTITEMCGATIPPGLLLELDRRAD
DPEAVLQLGVAYTTLQCADLLRRGAPGIHFYTLNRSPATRAILSSLRLQRPWDERQDDQL
EEVQPGGGSMSSA
>A0A168HIF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor lusitanicus CBS 277.49|TrEMBL
MKVVDKITKAENEGRTYWSFEYFPPKTEMGVQNLYDRMERMQRFGPEFVDVTWGAGGTSA
DLTMDIVATSQSVYGLETMMHLTCTNMPVESIDTALKAAKACGCQNILALRGDPPKGQLN
WESCENGFNHAVDLVRYIRKNYGDYFCIAVAGHPEGHIDNEDKEDDLLRLKEKVDAGADL
IVTQLFFDVDVFVQFVKRCRDIGITCPILPGIFPIQSYAGLKRVISFNNNTVPQKIWDDL
ESIKDDDQAVKDYGIDLAVEYVHQIKQQTGINGFHIYTFNLERSSRLILEKLGLVPEQEH
VKPLPWNPSLGPNRTKETVRPIFWKNRAQSYIQRTESWDEFPNGRWGDARSPAFGEFDRW
GVSIKYPVEKRLAMWGEPQSPDDIALLFAKYCKGRLEGLPWSAQKLEPETDTIKQRLAAI
NLLGYLTINSQPAVNGAKSNHPVYGWGPKNGYVYQKAYIEFFIPPSKLDELVQKIGADPE
VTYFAVNKNGDLRTNTVDDEPNAVTWGVFPGKEIVQPTIVEPTAFMAWKDEAFGLWNEWA
HTYDRQSLAAEVILDIYENWYLVNIVHNDFQDENGIWRLFDLEIDGDLSKKLRRGSGSL
>A0A3N5LPH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPHLAARMITDRSHLGAILDAITSAGITRTFVIGGDAPEPGKYLDALSLLRDMDDLGHPF
GEIGIACYPEGHAVIPSPPLLQALRDKEEYASYMTTQMCFDPNAIVDWITARRADGIALP
VHLGVPGVAELTKLVTLSARIGIGDSRRYLAKNSRLIGRLVRPGGFSADGLLDALGSHLA
GPSLAIEGIHLFTFNQVADTEEWRHRYLETLRHGHENEETA
>A0A2J6X1U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurihydrogenibium sp|TrEMBL
MKIIDKLKQVKTSVSFEFFPPKTKELEESLFNTIEELKHINPTFVSVTYGAGGSTREKTR
DVVKKIHEETNLTVMAHLACVGHSKYEIKSILDDYQRIGIENILALRGDIPISFEKENLP
SDGCKNAAELVSFIRENYRDYYCIAVASYPEGHPESPNLERDIYYFKKKVEMGADFSITQ
MFFDNNFFYEFIEKCQKVGINIPIIPGIMPITNFNQIRKFASLCGATIPEDVIKIFEKYA
DNPEETKKVGIEFATKQCEDLLKNGVKGLHFYTLNKSDATIRIYQNIKNLIA
>A0A522TV75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAEVVARSVKPTFSVELWPPRSPASAMKLEQTLPILEELHPTFTSITYGAGGSTREKTHD
LVVRIKRETSIEPMAHLTTAAHRKTELVLILERYIAAGVENILALRGDPPLSGDVELPPG
ELGNAIELVKLARSLGDFSITVAAHPEGHPDSPNLEIDRIMLARKLELADMAITQFFFVA
DDYFRLVDDLEKLGISKPVLPGIMAPTSLKTLEKMVQLSGAKVPNRVWQRLYGAGDDVEA
IKSIGVEIAIELSEELLKRGAPGIHVYTMNEAATTVEIYRSLGLG
>A0A1C7DAE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraurantiacibacter namhicola|TrEMBL
MPSDNAPDLSDFATQPIFAGLPGDIRVSFEVFPPKTDAGEDKMLDAVKTLATLGPDFVSV
TYGAGGSTRERSKAICERIAAEADVPVAAHLTCVNASKEETLEVADGLWNAGIRHIVALR
GDMPNSDGALDVPFQAHPDGYGCAAELVEGLAGLHPFEISVSAYPEVHPEARCADEALDY
LKRKLDAGASRAITQFFFSTDAFLRFRDCAAAAGIDKPIVPGILPVTDLARTRKMASECG
AEVPDWIADLFEGLDDQPQARELVSSTVNAEFCRRLYAEGVRDYHFYTLNKSKLAYATCH
MLGLRPVKPNKQEKAA
>A0A2E6VJ46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNYSLEFFPPKDQESFKDFIDQARLLSIFSPQYMSITHTANTIDNNLTMEAVKILKKNLS
VEIKPHMTCINYSKSEIMEMTQDYLSLGVDSIVALRGNTKQSASNREPYYDNSLDFIKAL
HAGFDIRVSISGYPEAHPESRGVIADFIYLKEKSDAGADEIITQWCFSNDLILRYRDLCY
ARDIKIPISPGILPISDIKKVKYFAKLCGSTIPLEIEKAFLNIEGNDDAAEDLGVQFAIQ
QIDDLLNEGIDNFHLYTLNRGDMTRKIIEHFEAPSRIKTVSSEMKAS
>A0A0F2IYE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Magnetoovum chiemensis|TrEMBL
MFKINFKTIMENNMRVSNLYGKKEKRVISFEFFPPRDAEAEAGFYKVVDELTALNPDYMT
MTFGAGGSTKDGSYQAVKKMIQEKKLPAAAYIAGYGLGQSEIITVLDRYKELGVETIFVI
RGDEPKNADFISQPDSFAYASDLIAFIKSRYDFDLGCAGYPEGHITAESIDKDTEILKLK
VDNGAKYIVSQYCYDNEKFFSYIERCRAAGIKVPIIPGIMPVYTVKLTRMLCKLCGSSIP
VSMEKKFEELSTADSKDVAAYGIEFAANQCRELLKHGVDGLHFYTMNRSKSVIEVINRLR
SEKLL
>A0A7V7WQ44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MATFSFEFFPPQTEEGMEKLRVTHRQLAQLAPAYFSVTYGAGGSTRERTLATVLELQQAG
SRVAPHLSCVGSTRESIRAILETYRGLGIQRLVALRGDLPSGMAEPGEFRYACDLVGFIR
AETGDSFHLEVAAYPEYHPQARSPREDLLAFQRKVEAGANSAITQYFFNADAYERFRDDC
EALGISIPIVPGIMPISKFSQLARFSDACGAGSSAGFRRRLESYGDDGASIRAFGLEVVT
DLCARLLRHGAPGLHFYTL
>M3GSC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira borgpetersenii str. 200701203|TrEMBL
MDFCIGGGCYPEKHPNAKSLEEDVRNLKRKVDAGTDFLVSQLFFVNSIFENFLNLVRKAD
IRVPVIPGIMPITSFSQIERFRSIAGCEFPSSLIEDLQEVEHRPEEFYRRSLNFSIKQCR
ELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A1E3B6J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus cristatus|TrEMBL
MSMRIHSIFNIGGRDRSRGQPLRSPLEDILPVSFALLSLPQFLVIVPSPRFSSKAIPILF
EMHVKEKLAQNEANEKTGISFEFFPPKTAQGVQNLYDRMDRMHSLGPEFIDITWGAGGRL
SDLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAALHAAYKAGCTNILALRGDPPRDKE
QWEVVDGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKIDAGSS
FVITQMFYDTDIFINWVKKCRAKGITVPILPGIMPIQTYAAFLRRANWTKARIPQDWLDA
LEPVKNDDAAVRDIGKTLIANMCRRLLDSGLIKHLHFYTMNLQQATQLVLEELKLLPSEE
TPLPKPLPWRPSLGLKRRAEDVRPIFWRNRNSSYIARTQTWDEYPNGRWTDSRSPAFGEL
DAYGVGLKGTNEQNIKLWGEPKSVQDITTIFIRYLKGELSRLPWSDTAISGEADAIMENL
INLNSRGFLTINSQPAVNGAKSSHPVHGWGPKNGYVYQKAYLELLVPNDVVDELISRIEK
NADLTYHAVSKTGNLRTNTLDSPNALTWGIFAGREVIQPTIVETVSFLAWKDEAYRLGED
WAKCHDAASPSRKLIQGVVDNWSLVNIVNNDFHNTYDIYQLFDGLNVKDLDVEVSGDALV
PQQNGASAEAAAAN
>A0A4R5UEU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas terrae|TrEMBL
MLPISFEFYPPKTDDQRTQLDRTAKKLAAHAPEYVSCTFGAGGSTLSHTPETVRRLKQQH
GFDATPHLSCVGGSREDIRELLKLYRAIGCTRIVALRGDLPSGMGQPGDLRYASDLVAFI
RSEFGDRFRIEVGCYPEIHPQSDDARADLRHFKTKVDAGADAAITQYFYNADAYFHFVDS
VRRAGVEIPIIPGVMPISNFSQLRRFSEACGAEIPRWMQRHMTAHGDDVEAVRELGADIV
TRLAERLIAGGAPALHFYTLNLAKPTQAVLARLA
>A0A5C6S4V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus aurantiacus|TrEMBL
MSTPAVSFEFFPPRNLDASFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALSN
HYGLNVAAHLTCVDASREETMQIVDEYAGAGVKEIVALRGDAPQGQAEWTAHPEGFTSSV
ELIEAISARGGMNIRVGAYPEPHPDSPGTAADVAFLKRKVDAGATSAITQFFFDADTFFR
FRDSCVAAGIDVPILPGILPIQSWAGARKFAARCGTSVPDWAITAFEAAGKQGEAQLATD
LCVRLCHDLIKGGVDHLHFYTLNKPELTLAVCRELGVSESGLAA
>A0A2B7XQX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicocarpus griseus UAMH5409|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDVTWGAGGRLS
ELTCEMVNVAQTVYGLETCMHLTCTDMPREKVDAALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYARDLVKYIREKYGNHFDIGVAGYPEGCEDQDDPELLMQHLKEKVDAGGTF
IITQMFYDVDNFLTWIKKCRESGINVPIIPGIMPISTYASFIRRSNWTKIRVPPEWMEAL
EPVKNDDAAVRNLGKSLVAKMCKTLLENGIHHLHFYTMNLQQATKMVLDELGLIPSHETP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHTSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIQLFGEPKSIKELSDIFIRFLNGKLERLPWSEAAVTEETEIIRSDLID
LNSRGFLTINSQPAINGIHSSNPIYGWGPKNGYVYQKAYLELLVPPTLIDDVLTRIEQNA
DLTYYCVNRAGELRTNTSDSPNAVTWGIFASKEIIQPTIVETVSFLAWKDEAYRLGDDWA
KCHAAHSPSRRLIQQVMDTWYLVNIVNNDFHKTHDIFNLFKDLKVKDLDVELEPLAPAAE
PAESTPQQSGQAEKQVNGTTAEAAEPKKESNAN
>A0A2D7U6A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp. MED195|TrEMBL
MIRLTSALQSSLQAGTLTITAEVMPPRGGDASHALAMARALKGLVHAVNVTDGSRAVMRM
SSLAVARLLLDEGIEPVLQMACRDRNRIAIQADLLGAHALGIRNLLCLTGXPVRAGDQPK
ARPVNELESVRLLQQVTXFNRGDDPVKGDLADGPTDIFAGAAADPQCASWSGLVRRXERK
KTAGARFIQTQMVMDVAVLERFCREIAEPMELPVLAGVFLLKSARNAAFINRMVPGACIP
DSLIXRLEAAPDPXAEGIQIASEQXKQYLGVAXGVHLMAIKAEERIPAILQRAGVSLPA
>A0A1E4JUS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium SCN 69-320|TrEMBL
MPATAPSRLPIPVSLEFFPPKTDEQRETLEKALPALKALNPEYVSVTFGAGGSTLSYTPD
TVCHLREQHGLDSAPHLSCMGGTRAEIRSLLQLYRSKGCRRIVALRGDLPSGMASYGDFR
YASDLVGFIRDETGDFFHIEVAGYPEVHPQSDDAQADLIHFKRKVEAGANGVITQYFYNA
DAYFRFVDDARRLGVNVPIVPGIMPITNYSQLRRFSELCGAEIPRWVARRLQSFGDDHEA
IREFGADVVTALCRRLVDGGAPALHFYTLNRARATTAVVERLQA
>A0A221Q633|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. 7749|TrEMBL
MSIATSVAPPSLSYELYPPASRDASESVFSTIAALESTDPDYVSVTYSGSPTRRAASLEL
IDHLIRDTRLRPLAHLTCVGESRESLQNLVRHFISLGVRGVLALRGDLPTKTDEWRGEFP
FARYLIELIREVEAEHSAALAGGRLGVGVAAYPIRHPESPSFDHDIEVLLAKERSGANYA
ITQVYFQASEYTNLVESAQRAGVTIPIIPGVIPLNSLKRLNRLASMTGVCPDPELAHALE
TADSEAERHRIGVAAAVNLARRAFDDGAPGVHLYTFNDHRGSLDVVEQLELPRTRAKVTR
TWATRAVA
>S9U0Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus alvei TS-15|TrEMBL
MKNFREALHEQIIIGDGAMGTYLYQLGYPVGISYEILNVTDPDVIRNIHKQYVDAGSGLL
ETNTFTANREKLYRHGKEHLVKDINRAAVRLAREAAGNQAYVIGALGSIRAGKRENVHTN
QVIRDYHEQMSAMLEEGVDGIMFETFYDLEEMRLALQVVRELDQDVPVICQFAVEESRRT
KDGKSLLEAFRVLRDDGADVVGLNCHMGPNGVLRALEGVQGRIDLPLSAFPNAGLPDYVD
GRYNFVASAEYMAQSAVKFVQMGARIVGGCCGTTPEHVAAIVEALRDVEVPKLPVQPVES
IIIEEESESMLWHDGAACYDGCDHGHDAEESIVDMVRSRHTVIVELDPPRDLDVSKFMKG
AQVLKEAGVDALTLADNSLAVTRMSNLALGYMALDKVGIRPLVHIACRDRNLIGTQSHMM
GLHALGIDHVLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNSGLAFSGKPLKQKAK
FVVGGAFNPNVKHLDKAIARLERKIEAGADYIMTQPVYDKELIVRISEATKHLNVPVFIG
IMPLASGRNAEYLHNEVPGIQLSDEVRSRMSGLEGEAGRKEGVVIAKELLDVALTHFKGI
YFMTPFMFYEMTAELTQYVWEKAERQADPLYRLT
>A0A8F6Y3D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. suillum|TrEMBL
MHSPMFTLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPGLKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRAAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNAEPLFLGTQG
>A0A1I4STM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ok602|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLNEYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VEFIREETADHFHLEVAAYPEMHPQARNFEDDLANFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVMIPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSESIQAFG
TQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A550G639|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ALS1131|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGDHFHIEVAAYPEMHPQARNFESDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSDSIRAFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLDLKR
>A0A1H2MZE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sihuiensis|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRVFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLPR
>R2RUU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus asini ATCC 700915|TrEMBL
MSHASLSFEIFPPNTHVGEEKLLGTLEQLGDLAPDFISVTCSNNKRNIEETTLKVAGYVK
NHLQIPTIAHLPACYLSKQQVTAILTQLEQLGIKQVLALRGDIDPQIPPTKDFSYASDLV
AYIKEAAPHFEISRACYPEVHPESKSHVADVLHLKEKVARGCDQLISQLFFDNEVFYRFL
EICQLANIQAPVLAGIMPIVNRKQALRIIQTADAKLPKKFLAILDKYEHNPVALRDAGLA
YAVDQIVDLITQDVAGIHLYTMNNAATARQIYQATASLFHKTPVLDQVLG
>A0A076HC29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. KORDI-49|TrEMBL
MTTALQRTLQAGNLAITAEVMPPRGGDASHTLAMADCLKGRVHAVNVTDGSRAVMRMSSL
AVCRLLLEKGLEPVLQLACRDRNRIALQGDLLGAHALGIHNLLCLTGDPVRAGDQADARP
VNEFESVKLLRQVSAFNSGEDPVQGTLADGATQLFAGCAADPQSRSWSGLQRRLQRKHDA
GARFVQTQMVMDAAALERFQRELAGPLQLPVLAGVFLLKSAKNARFINRVVPGACIPDDL
IARLEAAADPAMEGVAIAAEQVKRYLGIVQGVHLMAIKAEQRIPLILDQAGISISSLPG
>A0A0E3K3I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium scatologenes|TrEMBL
MSLLKEAFERGEFGITAEMAPPKGIDLSHLIECAKAIKVRAHGVNVTDFQSATLKATSLA
TCKVLKDAGLEPVLQITGRDRNRIAIQGELLSAGVFGIENVLALTGDYTMTGDHPGAKPV
YDLDSVGILSVASTIAQGKDMSGNDLTGMPKFYLGACVTPRYDPLELQILKMEKKIKAGA
KFFQTQAVYDIDTLKIFREKTKHLDAKLMVGIIPLKSAGMAKYMNKNVPGIFVPDELIER
MKGAENKVQEGIKISGEFIKKVKEEGLCDGVHIMAIGAEENVPLILDQAGL
>A0A1E5T9C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algibacter aquaticus|TrEMBL
MKVTDHIKKAKGKTLFSFEVIPPKKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYID
KGNGLLDKRITRMRPGTVGICASIMHKYGVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKDEAYFKPVKGGNAFASDLVEQIANLNKGQYLHDDVDVEHNSDFCIGVAGY
PEKHMEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNNKYFEFVDKARAMGINIPIIPGIK
PIAVKRHLQLLPQVFKIDLPQDLIDNVEACKDNKAVRQVGIEFAIQQSKELKAAGVPVLH
YYSMGKSDNVKAIASELF
>A0A2M9ZPV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira perolatii|TrEMBL
MKKILDIYNEAKGPVFSFEFFPPKTEEGEQKLYETVEELSAVSPGYITVTYGAGGSTRDK
TIRLTSDLANKFKLSAAAHFTCVGGDKDQIREILQEIESVGIRNLMALRGDPPKGEGVFQ
KTPGGFGNASELISFIKKEGFDFCIGGACYPEKHPEAPDLDEDVDMLKKKVDSGADYLVT
QLFFMNEKFESFLSLVRQKGISVPVIPGIMPITSFSQIERFRSMAACEFPPEFLVDLEQV
KENPAEFYKRSVRFSVRQCRELLDNGAQGIHLYTLNQSHASYDIVKQLQSIYS
>A0A319C0F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus uvarum CBS 121591|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKHHGDYFCIGVAAYPEGHPADNFQDGQDPARDVPYL
VEKTQAGADFIMTQLTYDIDAYTKFENMLRNHESGAFKTIPIIPGLMPLHSYKILTRVTK
LSHVKIPPHILSKLEVIKHDDDAVKRAGVDIVCDLVDGIRSIPTPGLRGFHFYTLNLEKT
VSFLLERCDLIGPYTEYDEPIEDSAAYSAARLETPALALASRRSSVSSMPHNRVIVDKLQ
PSDVSSRESVSHEATALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHILPAVAHKVWGYPVTHDDISALFRRHVSGELYIVPWSEGGAEEGSG
TLNAETEIIRPELLQLIDKRGWWTLASQPAINGVRSDDPIFGWGPPGEGFVFQKPFVEFF
CPSADYQTVLKPLFERHGHEKLAWFATNARGDFESSLPSSNAEDPDPIDINPANVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDSTKNDVWLVCVV
GQEFGAGTEVGSKEEEEETKWMWRELAGC
>A0A1L5QUM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas vesicatoria|TrEMBL
MAQPLIDPETSSLASALTADYSLEISANDIAGLAAAAPGMLRGSTIAIPYLPNQDDDARL
EAARRVRALGFQPMPHLSARRIGSRDALHTFVRRAVDEAGVARCLVIAGDPPVPAGPFPD
SLSLIETGVFERSGIQTIAVAGHPEGHPSMHATDQWDVLDRKCRSIAGRGMAPLIVTQFA
FDADIVLAWLQALRAHGIQHPVRMGVPGPAGVAVLARYAARCGVGACTAMLSKYGISLGK
LFGTTGPERFVDRLATGLTEAHGAVSLHFYPFGGVAQTVAWVERYRSRIARPGLD
>A0A1V5QRA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium ADurb.Bin340|TrEMBL
MVARLNSGQDLGGSPIGTAAAFSIGVGANPVAVDPERERSRFRWKVEAGAEWAITQPVFD
AEALFRFLDFAEPFGIPVLAGIWPLRSLRNAEFMAHEVPGVFVPPAILARMGRWTAAEDQ
VKEGLAIAQELVAAVRPRVKGLQIAAPLGQVDLLEDLLGAAKGGA
>C0WB69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidaminococcus intestini|TrEMBL
MKIKELLDSPKVTISCELFPPKKGTELQNAMDIVHAIAIDGVDYMSVTYGAGGTAVGKSL
AIASEVERSGVPALAHLTCIGAKKDGIARVLRDMKAGGIDNVLALRGDRPQGMDELPESD
FPHASDLVRFIKETGDFCVGCATYPEGHPESRTLDEDLENMKRKVDAGCDFLVTQMFFDN
EMFYNFMYRLLAKGVRVPVVAGVMPITNAKQVERIFTLSGTPIPSKLRAVVERFGDHPEA
LRQAGMAYTTGQIMDLIANGFNHIHVYTMNKPEVIGGIRRTLSEVIKL
>A0A7X3FGV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus lutrae|TrEMBL
MKPELRQALKQNVLIGDGAMGTYLYQQGFPVGISYEELNLVQSEVIADVHRRYYEAGARI
IETNTFSANREKLSKYGLEQEVDSINRAGVELARSSVGEDAYVVGAIGSIRAGKRKNVRT
SEVEVALREQILVLLDTPVDGLLLETFYDLDELLIALKLIRQLSPLPVICQFATEGTDAT
QDGVPLHEAFLRVRDEGADVIGFNCRTGPNGILRSLQNVAPLVDMPFSVFPNAGIPDYVD
GRYSYAATPEYFAESALRFANLGARIIGGCCGTTPEHIAAMAKVLQDYTPAEEAINELRA
AAQAVVTENAPQGSTSQPASEPSLVDLVKKRHTVIVELDPPRDLDIAKFMEGSKALQDMG
VDAITMADNSLAVTRMSNLAMGMLVKEQLKARPLIHIACRDRNSIGTQSHLMGLHALGID
HVLAVTGDPARFGDLPGSSSVYDLTSFEMIRMIKQLNEGIAFSGKPLKKKANFIIGAAFN
PNVKHLDKAVHRLERKIEAGADYIMTQPVYDPLLIERMYEATKHLKAPLFIGIMPLASGR
NAEYLHNEVPGIQLSDEVRARMAGLEGEEGRREGVAISQELLDAAMPLFNGIYFMTPFLF
YDMSVQLTKYVWEKAGRRDLLLSPLVK
>A0A6G8I2F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. CNU G2|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPEKVLAIHKAYIEAGADVIQT
NTYAAKRHRLDGYGYGDKIKEINQAGVKIARQAAGEDTFVLGTVGALRGLKQCELTLDEI
IKETLEQVGYLLETEEIDGLLFETYYDEEEIIEVLKAVRPLTDLPIITNISIHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVSRKFVTP
MVEEAELIKAVKQSETIVDKVKRKVTIIAELDPPKTLDIRKFTKGVKALDEAGVAAITLA
DNSLAKTRICNVSIASLLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIKQLNKGIGYSGASIKKETTFTAAAAFNPNVKNLS
RCGRLIDRKIAAGADCFITQPIFNSEIIENLAELTRDYETPFFVGIMPITSYNNAIFLHN
EVPGIQLSDDFLAKLEVVKDDKEKCQQLALEESKQLIDHALKFFNGIYLITPFMRYDLTV
DLVEYIHQKVEQSHQIIP
>A0A448UY76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia dentocariosa|TrEMBL
MTTVHPALSYELYPPRSHASCDSLLKTIAELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLALRGDIPPENTRSLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAARLAGVEMPIIPGIMPVTSLTRLTKLCELAGLEVPRELAHRLETASEP
REMHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>A0A1Z9SSS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium TMED264|TrEMBL
MRIRDKIKKPQRPVVAYEILPPREKDGTLNSYAETISSLLSQTHIDAINIPEVHDETGRG
ERPVSNQDRGEPRKFGMLLQDIVGIEAIINRVVVHTPIKEQMKWMEQTYTEYEIDNLIIV
GGESSKQKYPGPTVNQSLKKVSNMIIGDKKNIFCGGICIPSRKKESKNLIRKSECGAEFF
TTQVLCDSENIIKMINNYQKRCNKIGTFPRRILLSFAPVSSQKNINFLKWLGVEIPEGTE
KYLNGRPGSMTERSLDVAIEVLNETLSFITENNLKVPIGLNVEHIMSYNFQSSVEMLQEL
AKIYRKFCIKTQQYA
>A0A212AXP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haematobacter missouriensis|TrEMBL
MTTPRISFEFFPPQSLEASFRLWETVQALAPLNPAFVSVTYGAGGTTRKLTHEAVTTIHR
NYGLNVAAHLTCVDATREETLEIARAYAEAGVKEIVALRGDPPKGASGFTPHPEGFASSV
ELVEALAATGDFRLHVGAYPEPHPESSDTPSDVAWLRRKVAAGASSAITQFFFSPDIYFR
FRDAAVAAGVDVPIIPGIMPVNSWKGVRGFAARCGASVPASLDARFTAAVDSGREAAFAV
EQCTELCEALIAGGVEDLHFYTLNRPQLTQQVCANLGIRPASESAA
>A0A0C2FBD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporothrix brasiliensis 5110|TrEMBL
MDKITDKIAALSPESYYFSLEFFPPKTSMGFANLRGRLDRMARALRPLFVNVTWGAGGST
AQKSLELAEICQRELGLTTCLHLTCTNMSRELIDKALEDAKALGIRNILALRGDPPRPTE
YSDETDKDAAAAGIAPGPSGELAFSWAVDLVRYIRKQHGDYFCIGVAAYPEGHAEESHPL
GQSLEHDLPYLVEKVQAGADFVMTQLFFDHAAYAHFESVLLAHPSGAFKDIPLIPGLMPI
QNYQMIKRTTKLSHARIPDELMARLDAVKKDDEQVKSVGVDIISELVEEVKEIKDRTRAD
RPKGFHFYTLNLEKAVSFILERTHLIPPGTPDEDEEAIAGEVAVVDDVATSGSLGVPSIR
INGSTGTGGAVHPPLDGHPARRQSSIGSDPRNRVIVSGRAASHPDYEATALEASVPAEPV
NTRSNTLAISEGEGVLGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMTVNQALKLWG
RPTTTEDINAIFIRYLGGELAAIPWSEEEFNPETATIRDQLVQLNAKGWWTVASQPAVNG
IPSTDATFGWGPTHGFVFQKAFVEFFLPSADWAALCTRLTDPEVRDKVCFYAINAAGDFV
SSDASGRVTDGRGGAGAAEEASTNAVTWGVFPGKEIVTPTIVEEVSFRAWSEEAFGIWKE
WAALYPKGSPTDILLEKTRNDYWLVNIIHHNYIEKDSLWNLVSA
>A0A4Y7AJT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. WS1|TrEMBL
MTFDPVRGRSSEGWATRTPSIVDRIASSTGSRIPFSVEFSPPRDADAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSTEELRAMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPEGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
YDTKYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVSAYDAEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGPDENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTPDTSVGTAQAV
>A0A1H4L225|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter sp. 24-YEA-8|TrEMBL
MTKTPRISFEFFPPQGLDASFRLWDTVQALAPMQPEFVSVTYGAGGTTRKLTHEAVGIIH
RNYGLNVAAHLTCVDASKAETMEIVESYYEAGVREIVALRGDAPKGAAAWEKHPEGFASS
VELVGAIAKTGKFKVRVGAYPEPHPDSASTQADVDFLRRKIDAGATSAMTQFFFEADTFF
RFRDACVKAGITAPVIPGILPITSWDGAKKFAKRCGTDVPAKLDEAFTRAKRDGREELYA
LAQCTQLCDRLIEGGVEDLHFYTLNRPELTREVVRALGIQPQLVLENVA
>E1YLQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MNLKSKLEIGNFAILAELEPPKGVDVSLMLANAKRVKGIVDAFVVPEMSNAVMRMSSLGG
ALILNGNGLETVFQVNCRDRNRLALQADLLTAGAVGIDNVMAVSGEEPRFGDHHEAKAVY
DLDLIELIRTINSLNNGKDMAGIELSGSPRFIAGSTINSGASGHALTLELEIMAKKIEAG
AKFFITPALFDVNCIKPFLERIDLSKTKILPTVLLLKSAGMAKYIKQHMDNIIIPDAIIE
RIRKAPDRVRECIKIASETVSMLKNEGFAGAFVSTLGWENKLSEILE
>A0A136MUY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium OLB9|TrEMBL
MKITDHIIQAEGKTLFSFEIVPPRKGSGIADLYNNIDPLIEFKPPFIDVTTSREEYVFIE
KGDGLLERKITRMRPGTLGICAAIQHKYNVDTVPHVLCGGFSKEETEYLLVDCMYLGIQN
VMALRGDARKGEKYFEPASGGHQYASDLVAQIQDLGSGKYLHEAIISEELNSFCIGVAGY
PEKHIEAPSMEYDLQMLKKKVEAGADYIVTQMFFDNQRYFDFVERARAIGIEVPIIPGIK
PIATLNHLQILPQIFKIDLPQSLVKEVLKCKTNAAVRELGIEWTVHQCKELLEYNVPVLH
FYSMGQSDNIRRIAGHIF
>A0A1X2HPP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syncephalastrum racemosum|TrEMBL
MKIVDKLLQAEKEQRATYSFEFFPPKTEPGLANLFDRLERMARLKPDFVSCTWGAGGFTQ
EKTLEICSTAQSVYGLETLMHLTCTNMERSTIDEALEKAKEAGIQNILALRGDSPRGQEY
WTPCDTGFTHASDLVRYIREKHGDYFCIGVGGYPEGHMDAPDQATDLKYLKEKVDCGADF
ILTQLFFDVNTFINFVQRCRAEGITVPIIPGIMPIPTNQSFRRIINLCRIQVPKSILDDL
DAIRGDDQKVKDYGVNLATDMIKKILATKLVPGFHLSTLNLERSVRLILDGLDIVRQEPH
NLFPSKHAAKLMPWMAGRDHVENWDEFPNGRYGDARSPAFGENTYGASQVLPTSEAVLKW
GKPVEKEDITELFIKYIQGKLDNLPWCDEPLQTETDMIQQQLSQINRNGYWTVGSQPAVN
GVPSDDTVYGWGPKGGFVYQKAFIEFFVEDTQVPALLKKLRADPCVTYFATNQNGEFKTN
MDDEAQNAVTWGVFPGKEIIQPTIIERVSFLAWKEEAYSLWTEWEQQYPPESPTAKLLRD
VGQRYWLLNVVHNDFQEPDSLFDAMLS
>A0A1I1FFG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flexibacter flexilis DSM 6793|TrEMBL
MTKVTQHIANANNKTLFSFEILPPLKGESITGLFKGIEPLMEFKPPFIDVTYHREEYVYK
QRPNGFLEKITTRKRPGTVGICAAIMNRFHVDAVPHIICGGFSKEETENALIDLNFLGID
NVLALRGDAIKSEGVFVPEPDGHHYATELLGQITSMNKGQYLDEEMNAMYATDFCIGVAA
YPEKHFEAPNLATDIKYLKRKIELGANYIVTQMFFDNQKYFDFVKRCREEGITVPIIPGL
KPLTTRKQLNILPRIFHIDLPEVLAESIEACRTDADVRKVGVEWCISQSKELMAGGVPCL
HYYSMGKSESVRQIASALF
>A0A5N0TB55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenzhouxiangella sp. W260|TrEMBL
MTLTDAISAYHPGMPEIARYSHALQTKPFSICADLALDRHVGAGELRRQLAVLKPWVDAV
GVPDAHDGRLQMSAQAAAVLALAEGIDPVVRLTGRDRNRIALENDLFGLGALGVESVVLT
RGEALPPDYRPATRHVFELSGEDLVTTAHQLGEDDSVALGRPFCLGTAATVFAPKADWRP
TALAARVDAGVRFIQTQPCFNYRVLKRWMAHLVEARLTWRCAVIVSLVIPHTVEAARQLR
GQLPRALMSDRIENRMSAAPDPAAEAVALGAEKLAGLREIPGVSGVALTTPGPVELLARV
IETAGVPVAGSRK
>A0A0B4C0D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leisingera sp. ANG-Vp|TrEMBL
MMEHMLPSSYAPPPEGHVSHSRLEKVLRSGRFAITAELNPPDSADPSDVYDAARPLAEVA
DAINATDASGANCHMSSIGISALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAAMGVSNV
LCLTGDGVGVGDQPGAKPVFDFDSLSLLRTIKTMRDSGTFLSGRKITNPPRLFLGAAENP
CIPPYEWRPERLAKKVAAGAEFIQTNYIFDIPLFENFMSRVREMGLDKKVFILAGVGPLA
SARAARWMRSNVPGIHVPDALIDRMEKSSSPGEEGKRICVELIQQIREINGVSGIHVMAY
RKEHQVSEIINESGVLSSRSELA
>A0A7J9YIC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola sp|TrEMBL
MTSVVERLAGDAPAFSVEFFPPRDAADEAILWRSIRELEPYDPSYMSITYGAGGSSRDGT
IRNIARAATETTLVPMAHLTAVNHSVAELRNVIGHFAAVGVRNVLALRGDPPGDPNGTWT
AHPQGLNYASELVELLRSLGDFCVGVSAFPYGHPRSDDIESDTKHLVHKFRVGADFAIAQ
LFFEAEDFLRLRDRIAGAGIEAPVLPGIMPLTTPRTLRKTIELSGMQAPQWMLDRLEPLA
DDPKAFRVEGLNVVTELCERLLAEGVPNLHFYTFNRSKATRELVGRLGLVPVRA
>A0A7I4Y471|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemonchus contortus|TrEMBL
MSCVLMTGGSNPSLHERSGSDDEHLTFEVGRRRYIPLHERINRRVQDKTPFFSLEFFPPK
TANGVANFFTRLDRFNEGGPLFVDITWHLASDPANMNRETSSSSIAAGCLDYCRVDTMLH
MTCAQYSKEQTIKHLEQSKSVGLRNILALRGDLPHMDTDGVPIYKYRALDMIRWIREEFG
DYFTICCSGYPAGHPESPSYKADLLYLKSKCEAGAQFIITQLFFEAEVFEEFVRDCREIG
ITVPIIPGIMPIMGYDSIRRIATLSQLTIPESILSDLEPIKHDDDAVMKYGTVKAIEMCR
RILSNGSAPSIHLYTMNREGACREILQELGLWHKRPMRALPWDPLGSNHPLRCKEDVRPI
FWSARPKSYIYRTRDWDDFPNGRWGNSSSPAFGDLQDYYLFHLKAQTKKEDLLKMYGEEI
NSFDDVKKVFVNFISQGPNDRGVKVTSLPWNEQESGVQAETKLINEQLLWCNQNGILTVN
SQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFISKENAKSLLEIVDDYYPRVNYHLINH
DGSFDRMNGEQTTPIAVTWGVFPGAEIAQPTVVDPLAFRAWKDEAYDAWIKNWANIYPKD
SVSRKIIQKIHDEFYLLNLVDNDFQKPVIIYEVLEKMIKRTKETTNPTT
>A0A839AN49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum pelagium|TrEMBL
MKVTEHIKQANGETLFSFEILPPLKGQHIQSIFDNIDPLIEFKPPFIDVTYHREEYTYKE
LENGLLKKQVVKKRPGTVGICAAIQNKYQVDAVPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPEKDGHQYASELVSQIQDLNKGIYLDDELQNSSKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKNGATYIVTQMFFDNQKYFDFVAKCRKEGITVPIIPGLK
PISTQKQLNLIPHRFKVDLPDDLIMSVVKCKDNKTVRRVGVEWCIQQSKELIKAGVPLLH
YYSMGKSTNIQQIAKEVF
>A0A520KHR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanodesulfokores washburnensis|TrEMBL
MISLELNPPSRPSLDEIYEKIRRYNSFDAFIITELAMRREEDRWMDTMYTAIKLKEATGK
RIIPVMTSRESTKRGILSRILMAIHGGIDELVIVRGDQSPYGGAFGMTTVEIIRTIRSLC
ERFSKRVTVYVAANPTRDLEGEIVRAAEKLSSGADAVITQPTLDTNLLRKFIAGLRERGF
DNPVIGSIMILNSRNSAEMMERRCGIRFPEWFKEELERGNWRDSLLTSIREIADICDGVH
ISPIAEQDFSVLLAEEARKILRDRDEQLPIFLP
>H2MXI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzias latipes|TrEMBL
MVNQRVDGGWQACRSDSSGGSNSSGESSKDSSRCSTPLPDSDRGDRLRDKMRRRTESGDR
WFSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVN
YCGLESVLHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPIGTDWEEEEEGFNFAVDL
VKHIRSEFDDYFDICVAGYPTGHPEADSYEDDLRHLKDKVDAGADFVITQLFFRADTFLK
FLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEDITKVIEPIKDNDAAIRNYG
IHLAVEMCSVLLESGNVPGLHFYTLNREVATMEVLRQLGLWLEDPRRPLPWAVSANPKRK
VEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALL
QMWGEELKNEQSVFEVFTNYITAQPNQSGHKVMCLPWNDDPLAPETNLLKDQLEKVNRRG
VLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNY
HIVNVHEQNLTNAADMRPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKL
YEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPELLGTETT
>A0A651ECH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTQSALTARPAVSFEFFPPKTPAAAANLWASVERLAPLGPQFVSVTYGAGGTTRERTVAA
IMAIRDRAGLDVAGHLTCVGATREETLAVAETYAKAGCTRIVALRGDPPKGEGRFTPHPG
GFESATELVAGLAAAGWKRIAVGAYPETHPEAASPQADIDNLKRKLDAGATEAITQFFFE
NATFLRFRDACARAGITAPIIPGILPIENFAKMRRFAEGCGAGVPVWLAQAFEHAETQDA
AELLSVSIAAEQCAGLLGEGIDHLHLYTLNNPDLPYQVCRAIGIEPRPMRIAAAGGCG
>A0A2N2AM43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-8|TrEMBL
MCESGNFVVTGEIGPPKSCNGEIVRHHAKMLKGWCESFNLTDNQTAIVRLSSIAAGKILL
EEGLEPNIQIVCRDRNRIAAQSDILGASALGMKNVLCLSGDHQKFGNHPTAKNVFDVDSI
QLIQILDGMRKGYFANGEQMKDEPPQLFIGCAANPFADPFEFRVTRLEKKADAGADFCQT
QCILDMERFERWMELVRARGLHKRIKILGGITPIKSVKAAKYMKKFVAGMMVSDDLIERL
EKAEDVKAEGLQIAIEQIERLKKMEGIAGVHIMAIAWEEKVPEICQRAGLAPRPEV
>A0A4R1YHJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK068|TrEMBL
MALNSAARRKIGISFEFFPPKSEEMEGQLWNTVSELQDWDPDFVSVTYGAGGTTKAPTLA
TVSRFLAETPLATASHLTCVGATKDETHSVIETFRKVGVKHFVALRGDAPGGVGAPYQPH
PGGYANAAALVAGLREIGDFEISVSAYPEKHPESRDTAADIDMLKQKADNGATRALTQFF
FDNDNFERYLEQVRAAGINIPVVPGIMPIQNLTQLKRFAGACGTLIPAFLDERFAGFDDK
PEERAKVAAEVAAEQIEDLARRGLTDFHLYTMNRAPLVSAVLTNLGFTRDGAKKAGAAA
>A0A328C1X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaesserella australis|TrEMBL
MSYAREIDLLNQSVADLNGKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKTIQQETGIIAAPHLTGIDATPEELRQIAKDYWDSGIRHIVALRGDEP
PGYNKKPFYASDLVKLLKDVADFEISVAAYPEVHPEAKSAQSDLLYLKQKIDAGATRAIT
QFFFDIDSYLRFRDRCATIGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMSKMYQGL
DDDQTTRNLVGASIAMDMVKILSKEGVKDFHLYTLNRSELSYAICHTLGIRPE
>A0A841UMY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa BLCC-F108|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>A0A840URT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoprunum benzoelyticum|TrEMBL
MKTESKLEKVLAAGHLAVTSECGPPRGCMPDKVREKGKYLEGVVDAINVTDNQTAMVRMS
SLAASAILRQEGLNPLLQVVSRDRNRLAMQADIIGAYSLGIDTMLCLSGDHTKFGDHPMA
ANVHDIDSIQMIQMVKRMRDEGLFQGGAELKNPPKMFIGAAANPFADPFELRVLRLAKKI
AAGADFIQTQCIFNVDKFEKWMEGVRSMGLHKKCYILAGITPIKSVGAARYMKNKVPGMD
VPQEIVDRMAAQPKEKQPEEGITICIETIERLKKIEGVAGFHIMAIDWEEKVKEIVERAG
LLPRPVV
>A0A1W9ML86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium IS3|TrEMBL
MKLTELFDKGEFVITSEVGPVKGCLRSIAGSKLPQCAQEAELVRSVAHAINVTDNQSAVM
RLGSLAASVKLKERGFEPIYQMTCRDRNRLALQSDLLSACSLGIDNVLCLTGDYTSLGDH
KSAKSVFDIDSVQLLKIARGLNEGHDMMGNALTQSTNLALGAVVNPNFEPLDLQLLKMEK
KIEAGAQFFQTQAVYDPRVFEKMVKKTEKFGVPIQYGVVTIKSPQMGKFMNENVSGITVP
DWIIEEMGKAAKQDRKKKAIEITVRLIREIKPMVQGIHFMPLGWSDIVPTIMEAVKSAI
>A0A1B3LRF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloversatilis sp. RAC08|TrEMBL
MNDSTPRVCSVEFFPPATDEGAEKLRATRRQLRQLNPAFFSVTYGAGGTTRDRTLETVLE
MQAEGLNAAPHLSCIGSTRDNIRQLLQRYQAEGIHHMVALRGDLPSGVVDPGDLRYANEL
VEFVRAETGDWFHIEVAAYPEVHPQARSAEKDLQAFVGKMKAGADSAITQYFYNTDAYFA
FVDDARAMGVDAPIYPGIMPIANFSKISRFSEACGAEIPRWMRRKFEGFGDDAASVRAYG
LDVVTTLCERLLAGGAPGLHFYTLNQAGLTSTIWQRLGL
>A0A5B7XJG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leclercia adecarboxylata|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMAKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A140NHQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli (strain B / BL21-DE3)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2M7PBH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_10_14_3_um_filter_60_8|TrEMBL
MNNAHCFQTSLRDPEDFTLTFELVPSRGGRSHEHGRALDFAREAVQDGRLRAVSITENAG
GHAALSPEVLGVEILHLGLDVIVHFSCKDKNRNQMESLLFAWDRLGLRNLLVLAGDYPKP
GYQGLPKPVFDLDTVQALDLVGRMNQAIFGADQLSALADPAEATAFFRGVVVSPFKYLEA
ELRMQYAKLHRKAAAGAGFVITQLGFDARKFQEVLLYLRANHLELP
>A0A1I3T4I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myroides guanonis|TrEMBL
MKVTEHIEKAKGNTLFSFEILPPLKGQNIQAIFDTVSPLMEFEPPFIDVTYHREEYDYLD
AGNGLWQKRIVRKRPGTVGICSAIQSKFKVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPERDGHHYASELVTQITALNQGIYLDPHLENSNKTDFCIGVAGY
PEKHMEAPNFDTDLRYLKEKIDCGADYIITQMFFDNQKYFDFVDRCRKEGITVPIIPGLK
PLATARQLNILPHRFKVDLPDELVAEVLTAKTSEQIKEIGSAWCVHQTQELLKAGVPIIH
YYSMGKPDTISDIIHRSTL
>A0A252BYR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter okinawensis|TrEMBL
MSLNRLCVELIPRSAESLAQDVETVKTVFPVADTLNIPDLMRFPLRSWDAAALLRPTFPH
VIPHIRAIDIAPDAPLPGAAQEGLEEILVVHGDPPADLSMRTYPNSTESIIRRYRREAPH
LKIYAAFDPYRRAPWKELEDIARKKEAGASGFFTQPVFDYKLFDLCREWLQGEDVFWGLS
PVIGPRSRSYWETTNHIVFPKDFSTTLESNIAFAQRVLRELARDQASAYLMPVRIKLEQY
LPALLEAAS
>D9VS35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. C|TrEMBL
MALGTASTWSDRAHTVRDLLASGASYSFEFWAPKTEKGERNLWNALRRIEAVSPSFVSVT
YGAGGSTRGGTVRATQQIASDTTLTPVAHLTAVDHSVAELRHVIGQFADAGIRNMLALRG
DPPGDPMGPWVRHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVAKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
DAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A3N6BY01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rummeliibacillus sp. TYF005|TrEMBL
MGLLEKLQSQVLTADGAMGTLLYSYGIDYCYEELNVKKPEVIENIHQQYIDAGADIIQTN
TYTANAIKLERYGLENSVKAINESAIQIAKKVASKGEQFVLGTIGGIRGIRKSDATLDEI
IRSLDEQAGILLAGNPDGLLLETYYDFDELKAAVKHLRRITDVPIISQVSMHEPGILQNG
LRLNDALHQLEAIGADIVGVNCRLGPHHTIQAFEDVELPSKAFLSAYPNASLLDVEDGKI
VYESEAEYFGRSAVLLRDQGVRLIGGCCGTTPKHIEAVKHRLADLPPIQHKVVKHKEVIL
IKEATKESYKPLHEKAKKERSIIVELDTPRHLEIEKFIEGSKALYEAGADAVTMADNSLA
SPRISNMAMGSILKLNNNIRPLAHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPSKV
GDFPGATSVYDVSSIELLQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVVERAVGR
LEKKIEAGADYFITQPVYSKEKIIEVYEATKHLETPIFIGIMPLTSVRNSEFLHHEVPGI
KLSEEVLERMRATGEDKEAARFEGIAIAKELIDTAAELFNGIYLITPFMRYDMSIELMNY
IRELDFKREDESNYVKASH
>A0A497SLU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aenigmarchaeota archaeon|TrEMBL
PTGFHLGVGANPGAINLDYEIRRFEYKVEAGAEFAITQPVFDIRLLENFLKRISHCRIPI
IAGIWPLASLQNAEFMNNEVPGARVPPEIMDRMRKANEKGSEFARQEGIAIAREVLSEIK
DMVEGVQISPPFGRVEAVKEIISIL
>A0A7Y6A279|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas humilata|TrEMBL
MSAAVAEPRTPGLHAATARRAQTANDRPTISFELFPPRNPDAAPRLWSTIRALESVHPDF
VSVTYGASGKTRVTTRALVRRLLRETTLNPIAHLTCVGTSREEITTIVGEFLDEGLRSFL
ALRGDPPTDQSDWAAHPEGLQTAGELVELLRDIEAQRCLDSPSQAVRARVRPLSVAVAAF
PRGNHATGGTRAQDVASLLAKQQAGADFAITQVFFDADDYLGIVAEAREAGVTIPIIPGI
IPTTDPARLLRVQELTGVPVPSDLIDLLGSADDELDRHRRGIRASVDLVNGVLDGGAPGV
HLYTFNQHHAALDLLEGAHLDGGARTAPDLASWPQDTAPRPTPRD
>A0A8B7A0D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orycteropus afer afer|TrEMBL
MDHLKARALPARHSCPSPGMRAWEASSARFSVSPSISRTLAMVNEARGSSGPSPHLEGSS
SGSESSKDSSRCSTPGLDPERHDRLREKMRRRIESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCRQSREEITG
HLHRAKRLGLKNILALRGDPIGEQWEEEEGGFSYATDLVKHIRSEFGDYFDICVAGYPKG
HPEAESFEADVKYLKEKVSAGADFIITQLFFEADTFFQFVKACTEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVRLCKELLASGLVPGLHF
YTLNREVAIIEVLKRLGMWTEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFAHYLS
GEPNQNGCKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSREMVEALLQVLKRYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYVHDNYFLVN
LVDNDFPLENCLWQVMEDTFELLNRPTPE
>E1SI77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea vagans (strain C9-1)|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWTSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMSAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPIAAAA
>A0A2A3BRA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM4308|TrEMBL
MSARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A3M3R6A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. apii|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1M5HXA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium erythrophlei|TrEMBL
MPISEFTPPAPDGHRTPAISFEFFPPKTEEMERSLWETIKRLAPLSPSFVSVTYGAGGST
RERTHSTIARILKETELLPAAHLTCVGAARGEIDDIVGRYRDIGVRHIVALRGDPPGGIG
TPYSTHPDGYQTSAELVAGIKRQHGDIEVSVSAYPEKHPESRDFDADIDVLQAKVDAGAD
RAITQVFFDNDLYLRYLDRVRARGIAIPVVPGIMPMHNFKQARNFVTRAGTTVPDWLAAK
FEGLDDDAETRKLVAATVAAGQVQKLAKHGIDTFHFYTMNRADLVFAICHLLGIRPKGAQ
KAA
>A0A1D7XZA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Formosa sp. Hel1_33_131|TrEMBL
MKVTDHLKNANGKTLFSFEIIPPKKGKNIQELYNNIDPLMEFNPPFIDVTTSREEYIYIE
KKGLFDRKITRMRPGTLGICAAIKHKYEVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDTMPHQKYFEQTKGGHNYATDLVQQIHKLNKGQYLHDVEEVDNKPDFCIGVAGYP
EKHIESPSLHSDLLRLKEKVDAGADYVVTQMFFDNQRYFEFVKMAREMGITVPIIPGIKP
LAIEKHLQLLPQVFKIDLPEALIKEVNKCDTNAQIRQVGVEWTIQQSKELLDFGVPVLHY
YSMGKSDNIKAIASQLF
>A0A426Q5G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium bovis|TrEMBL
MCQESPGATTHRRSHQIAVSDTLTFTTPGRVPFSVEFMPPRDDAAETRLWNAAEAFHDLG
ASFVSVTYGAGGSSRRRTLRVARQLARKPLTTLVHLTLVDHTRDELRAILRDFADQGLTN
LLALRGDPPGDPLGDWVPTDGGLNYASELIDLVRSEPGCEDFDIGVASFPEGHHRARDLE
EDTRHTLAKLRAGARYSITQMFFDVDHYLRLRDRLAAADPEHGAKPVIPGLIPITSLRSV
RRQMELAGAALPAELERRLLRAAAGDEEANRPAVREVGIELTTTMAERLIAEGAPDLHFM
TMNHPRATQEVLHNLGMAPAWGPQWGQDAVR
>A0A0F0HEE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentzea aerocolonigenes|TrEMBL
MTSVVERLQGQSPKFSVEFLPPRDAEDEKILWKAVRELEGLDPAFVSITYGAGGSRRDRT
IRATGRIAQETTLLPVAHLTAVDHSVAELRNVIGWYAAIGVRNVLALRGDPPGDPMGEWV
AHPEGLNYADELVSLVRELGDFCVGVAAFPYGHPRSNDLDTDLKFLLRKLNAGADYAVAQ
LFHEPEPFLRMRDRVAAAGCSAAMLPGIMPMLSARGLSKIVELSGADLPVEISRRLEPYA
DDAAGFRATGIDIATEMCQKLLDEGVPALHFYTMNRAKATREVLGRLGLVARA
>A0A257GQ06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodobacter sp. PARRP1|TrEMBL
MTAPRISFEFFPPQSLDASFKLWETVQVLAPMQPNFVSVTYGAGGTTRKLTHEAVGTIKR
NYGLNVAAHLTCVDASRAETLEIAEAYAEVGVTEIVALRGDAPKGADRFTPHKDGFAHSA
ELVEALAKTGKFKIRVGAYPEPHPDAADRFADVTWLKRKIDAGASSAITQFFFEADTFFR
FRDACVKAGISAPIIPGILPIQSWDGTKKFAARCGTSVPQRLDEGFAAAKRDGREDLLAL
TQCTTLCSRLIEGGVEDLHFYTLNRPELTREVVRALGIAPELAPQIALEKVA
>A0A2A4MU16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR86 cluster bacterium|TrEMBL
MNATNTNNSPKFSFEFFPPRTSVGEEKLRAVHKQLAALNPEFFSVTYGAGGSTRSGTKQI
VLDIHRSGSAVAPHLSFGGSSETELEQLLLDYKTAGINRLVALRGDIPSGTGSIAQFRYA
SELVEFIRARTGDFFHIEVACYPEIHPESTSYDADLDFFKKKVDAGADSAITQYFYNADA
YFHFVDSAAAKGVSIPIMPGIMPITNFANLARFSAGCGAEIPRWISQRLQAFGDDKASIQ
EFGLEVVTRLCEKLLAGGAPGFHFYSMNQADSVSTICKNLGLSSS
>A0A556N275|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fluviicola chungangensis|TrEMBL
MKVIDHLNAAKDTLFSFEILPPLKGANIQSIYDGIDPLMEFKPKYINVTYHREEFIYKER
EKGLLEKIAIRKRPGTVGICAAIMNKYYVDAVPHLICGGFSREETENALIDLQFLGIDNV
LALRGDSIKTESTFKPDPEGHKYAVELINQISEMNKGNYLVDDIQLAPTDFCIGAAGYPE
KHFEAMNLSTDLQYLKSKVEAGAEYIVTQMFFNNQKYFDFVDACRAIGITVPIIPGIKPI
TTLNHISFLPKVFHIDLPEELSKDLIKCKSNKDVFEVGVAWGIHQSQELKKANVPGIHYY
TMSTSESVKAIAEQIF
>A0A0F7JP26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus soli|TrEMBL
MTRVSVELVPRSRSGLRAEIAEVAGALGGVDTVNVPDLTRYSLRSWVGCGFARPGFAAIP
HLRAVDFNPREPLPFLPLLEEHGIREVLVVTGDAPIDMSARVYDQDAVDLIRRLNRDAPH
LRVYAGLDPYRQSFVRERDYLERKLDAGAAGFFTQPFFDLRLLDTWADLLPDGTDVWWGA
TSILTEASFNYWRARNHAVFPRTFTPTLDCNRAFARDLLTFAREREQHAYFMPVKVNVLE
YLGGIL
>A0A1L8QUG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus aquimarinus|TrEMBL
MLQGLSFEVFPPNTTIGVNKLTQTLKELQQLQPAFISVTCSNGTNHVADTTVKVASYIHQ
ELHIPTIAHLPATYLSKEEVDEVLQQLDQLGIHQVLALRGDILTDVVPKADFKYADELTR
YIKEQAPQFQLTGACYPEMHPESSSRITDIQNLKKKVDAGCTQLITQLFLDNELFYRFQE
SCYLAGIDVPILAGIMPIVNRNQALRLLKTTQTQLPRKFLAILEKYEHNPIALRDAGLAY
AVDQIVDLVTQDVSGIHLYTMNDAQIAQRIVENTHSLFGENKVRVG
>A0A369AGC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Extensimonas vulgaris|TrEMBL
MTARPPPPMKQATHEASARLPLSFEFFPPKTPEGVEKLRTVRRALYALAPEFCSVTYGAG
GSTHEGSFATVREILAEGVPAAAHFSCIGATRASVRAQLQELQAMGVRRLVALRGDLPSG
YGLGGEFHYASELVEFIRAETGRHFHIEVAAYPETHPQARSPAADLQAFAAKLRAGADSA
ITQYFYNADAYFRFVDEVQRLGADVARVPIVPGIMPITGAAQLLRFSDACGAEVPRWIRL
RLQAFGDDTASIKAFGLDVVAALCERLIAGGAPALHFYTMNQSAPTLAICARLQGAQQG
>A0A7X3MGU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporofaciens musculi|TrEMBL
MKIRDILKSEEPHISFEVFPPKTDAGYDSVLSATRKIAALKPSFISVTYGAGGGTSKNTV
SIATQIEKDFGVTSLAHLTCVSSTKEEVHRVIDQLKENQIENILALRGDIPSESEFPLPS
HYRYASELIEDIRKQGEFCIGAACYPEGHVETEHKKDDIRNLKHKVDCGVDFLTTQMFFD
NNILYNFLYRIREKGITVPVLPGIMPVTNKKQIARIGGLSGTILPERFRAIVDRFGDDPG
AMQQAGIAYATDQIIDLIANGVNHIHVYSMNKPEVAEAIMRNLSEIVA
>A0A6H0ZJ85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium pusense|TrEMBL
MIIKRIMHTLPDISATSVIPASIEASPAQVLGPASLAGLFPQGVRVYLTDTGAASQVKLV
DAAKHLRDLGYEPVPHLAARRIASRIDFEEQVKRLAGDAGVTDVLAVGGGVEKPEGPFTS
TIDMLSTGIFDRCGIKHIAIAGHPEGSPDFNDETATAALRLKRDFGERTDAAMRIVTQFG
FDSARFIAWAEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LARGHSPESIVGPIERHWRDNPQGPIRQIHVFPFGGLQASSDWLVSRGSWRTKNADHAAA
TGSVAI
>A0A6P0GCA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas perforans|TrEMBL
MISTDTPNFASTVTEAYSLEVSAKDIGALTNAAPRILPGCAMFIPYLPGQNQAVRLAAAQ
MVRSLGFEPVPHLSARRIGSLGELQACIARLVDEAGVTRCLVIAGDPSTPKGPFPDSVSL
IETGVFERSGIRTIGVAGHPEGHPILRTTEQWEVLERKCRSIQERGMAPLIVTQFGFDAD
IVVTWLEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLASRLTEAHGDVRL
>A0A1E4SSH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Suhomyces tanzawaensis NRRL Y-17324|TrEMBL
MATVKERIAALQPGQKFISFEFFPPKTDAGFRNLLSRLNRMLALNPLFITVTWGAGGSTS
EKSLDLASTCQNHLGLTTVLHLTCTNTNREIIDQALAKAKQAGIRNILALRGDPPRTQEY
WTPNCDFNSAVDLVRYIKSHYGDYFCIGVAGYPEGHVDGSGSGQPEQSPTRDIPYLIEKV
EAGADYIISQLFFDGAKFLQYEQLLRSYPQLKDITLIPGLMPITTYLVFQRASKLSHASI
PKAVEDRLKSSIHNDDLIKSIGIDIVTELIDEIDSKTDGRIQGYHFYCLNLEKAVASILQ
KSSILRPIMEAPSSGMNLEDAIASDDEENDIAVIQGPKRRQSSIVNDNEVVNAQRSLVSK
ALLNDKKLLVDISRGKGALGKDATWDEFTNGRYGDSTSPAYGDFDAYGPNLKISSPQEAI
RNWGSPTSKKDLSKIFVNYLLGKIDVLPWVDTGLSSETALIQEELLQLNERGWFSLSSQP
SVNGCPSSDKIFGWGPTNGFVYQKSFIEIFIPKEEWETKLLPKLANHIEEKTITYYLGDA
TGNIESNLRIDPANPHISRSAITWGVFPLKEVLQPTVIDFDSFKVWNEEAFNLWLDWSKC
FKKDEESFKFLSDIRQNYYLVSIVYHNFKQETGLWDLLLNE
>A0A0Q4QJ97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf67|TrEMBL
MTPTISDLEEARRALDAPLFADLAGDCAVSFEFFPPKSDKMEAALWETVRALEPLAPKFV
SVTYGAGGSTRERTHATVARIARDTSMPAAAHLTCVEASRAEIDQVAEEYWQAGVRHIVA
LRGDPPTMGQKFVPHADGYANAADLVAGLQKLHPFEISVAAYPELHPDSEHQQADLDNLK
RKIDAGATRAITQFFFTPEAFFRFRDAAAAAGISAEIVPGILPVSNVGQVRKFAGLCGAS
IPAWMDRLFEGLDDHPGARQLVAATVAAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPRATPVVAAA
>A0A1X7LXU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cedecea sp. NFIX57|TrEMBL
MSFFHANQREALNQSLAEVAGHIHVSFEFFPPRSSEMEQTLWKSIDRLSILKPTFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELRSIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLLSLRRKIEAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFRQAKKFADMTNVRIPSWMAQMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPKL
>A0A1F1JTG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kytococcus sp. HMSC28H12|TrEMBL
MTRISVELVPRSEESLLTEAASLSEVAPWADTINVPDLVKFDLRPWVGCRKVREATRRPD
GSPYGVIPHVRACDVDPDAPLPMAAEFRAAGITEVLVVSGDDADYFSQHTYPVDAVDVIR
RFRQELPGVRVYAALDPYRTGMSAELRQVERKLVAGASGVFTQPFFDVDHLRSWRRVLPD
EVEVWWGATTVTTLAALGYWRRRNLVAFPRDFRMELQAQREFAQRTIDLATEWGDNAYLM
PVRTAPAEYLAGLRVPAAA
>A0A5J4R2A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
MRIIDLISGNERTAFSFEILPPLKGTGIGKLCETIELLQEFNPKYINITTHRSEYVYADS
GNGLYQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLIDLQFLGITDL
LVLRGDKAKHEPVFIPEENGCLHAIELQEQINNFNKGIFIDGSRAKEVIAPFSYGVACYP
EKHEESPNIDNDIYWLKKKVEAGAEYAVTQLFYDNKIYFDFVEKTRKAGIHIPIIPGIKP
FKKLSQLSMIPKTFKVDLPGELSREVLKCKSDDEAQQVGIEWCTAQCKELIARNVPSIHF
YSSAAADSIREVAKRIY
>A0A1B8QF53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella atlantae|TrEMBL
MTTPFSIEFFPPKTDDAAAKLLHTFAELNALQPEYFSVTYGAGGSTRARTLGIVKTLNEA
SATPIAPHLSCIGDGKAEIAELLDTYTALGISKIVALRGDLPSGQVGFGELPYAVNLVQF
IREYAGERFEIEVAAYPEMHPQARNFASDIDNLVAKYRAGASAAITQFFYNPDSYLYLRD
ALAKRGVQPEDFALKAGIMPITNASNLIRFADACGADIPRYIRRQLADFGDDRAAIRAFG
FDVVMRLCERLIAEGVPALHFYSMNQVNPTKALIEALGLRQAVDLTFNQTTKSIQA
>A0A4Y8STZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. RIT623|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALLAEYQAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAGKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVISRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A5J4SMM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
MRIIDLIHNSQRTAFSFEILPPLKGTGIEKLYDTIDTLREFDPQYINITTHRSEYIYTDC
GNGLYQRNRLRRRPGTVAVATAIHNKYHITVVPHILCSGFTKEETEYVLIDLQFLQIADL
LILRGDKAKHEPVFTPEENGCLHAIELQEQINNFNQGVFIDGTKAKTPAFPFSYGVACYP
EKHEESPNIDSDIYWLKKKVEAGAEYAVTQLFYDNKKYFGFVEKARKAGVNIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEALLNELLKCKNDDEAQQVGIEWCTAQCKELIAHKAPSIHF
YSVAAADSIKEVAKRIY
>A0A0P0G2Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides cellulosilyticus|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYDTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNRYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELAYEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A1V0A3T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea sp. ATCC 55076|TrEMBL
MALGRSSIRPDRVPTVREMLASGGRSFSFEFFPPKTDEGARQLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERIAHDTTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVR
GDPPGDPMGEWVQHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSVESDVEYFVR
KCRAGADYAITQMFFQADDYLRLRDRVAAKGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPDVAARFEAVKDDPAAVRQLGIEHGAELCQRLLDEGAPGIHFITFNRSSASREVFQRLE
RVPAAT
>H8MPX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2)|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTVEELAPLEPGFVSVTYGAGGSTRDRTV
DLVTHIKEKTGIEAMAHLTCVGHTRDELRDVLRRLDAAGIENVLLLRGDPPQGQTTFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVGALKGRS
>A0A840IGZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Conexibacter arvalis|TrEMBL
MRIDEIIAAGGEPVFSFEFFPPKSEEGEARLFAALEALRPLEPAFVSVTWGAGGSTRTKT
IEIVSRIRDNHDLEAMAHFTCVGATRDDLHTALKQMRAAGIQNVLALRGDPPKGETTFRP
TEDGLAYASDLTRLVAEGYPEMCLVGACYPEVHTEATDRESDLRHLKEKVDAGARVLITQ
LFFDNAHYYRFVEDARAVGIDVPIVPGIMPIISAAGVKRMTALGGSTIPPALLEALEARA
DDEEAVAELGVAYATLQCAELLANGAPGIHFYTINRSPATRAILSALRLQRPWEKGAGAE
PALKVAAG
>A0A855LVR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FW104-15G4B|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVTEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A8F9VS80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. DSM 110486|TrEMBL
MTSVIERLQGDGPRFSIEFFPPRDEADEAVLWRSIRELEPFDPAYMSITYGAGGSSRDGT
IRSIARVATETTLCPMAHLTAVDHSVSELRNVIGWYAAVGVRNILALRGDPAGEVYGDWV
PHPEGLTYAEELVELIRSLGDFCVGVSAFPYGHPRSPDLESDTKYLVRKFRAGADFAIAQ
LFFEAEDFLRLRDRVAAAGCDALVLPGIMPLTTLRTLHTTIKLSGAPASQRLLDRLEPLS
DDPKAFRAAGIDAVTELGEKLIAEGVPDLHFYTFNRSKATREVVTRLGLVPARA
>A0A6I6SCY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas tianxiuensis|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGKFAITSEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGAHCHMSSVGVCSLLTRVGYATILQISCRDRNRIAIQGEILGAAAMGAC
NLLCLSGDGVQAGDHPQAKPVFDLDSMSLLEIARGMRDECRFQSGRKIDVPPRIFLGAAE
NPFVPPLEWRPHRLAKKVAAGAQFIQTQYCFDIPRLRDFMLKVNDLGLLEGPDRVFILPG
VGPLASARSARWIRDNVPGVHIPDAVIARLEGAQNQKEEGKRLCMDLLHQIREIPGVSGA
HIMAYRQEHTVAEIIEGTGVLEGRVPWYPGRDNPAELNPESPDALAEEFEPVSG
>A0A3C1APP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSVLKAALQQQQFACVMEFVPKPSAERFAAMDAIMARRQLCGWPMTLAIGDRVSSPLDMS
PLDALACFEHPVPALPHFSGKDRERHHLLAQMRRMDAAGQHQLLMLTGDRLPGHTPGKRP
VRYLESVAALQIARQAYPHWWLGAALNPFKYREEEGAAQYLKAEKKLAAGADFFILQLGF
DAAKHQEAMHWMRRQRAPKPMLACLMSLTQGRAGMLDHVAGVTVTPSMRQMLEAEAAQSK
AFAQARSIDRLALQVIGVKLMGYAGVHLSGIHEPSQLLALEARLAHWQTQVATLEQWAPA
WQASWQMPGLPAVTFHPPQAAWREGESRVVASFAQKARYHAMHGMHGLLFSRRNPVSQLF
GWAVRQPMWATGLGAQVLHSVERAVKRPLLGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTTLNRCEFGDRECIHSAKYRTAKAVRQTDVLAQRLIPCVEQHTRHRSSWPGWFGAQAQ
PVTRPSAPRSRPES
>A0A3C0QSD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MIYSFEVFPPKPTAPVEAVSETFAELATLKPDFISVTYGAGGGVTGGQLTCELSARLKNE
YHVKPVAHLPCISYTKEEISSVLEQFKEYGITDILALRGDKSPERPEKHDFRYASELIDF
IRTKGDFNLYGACYPEIHPEARSAADDIRHLKEKVDKGATHLISQLFFDNNSFYQFLEKC
DIAGIHVPIEAGIMPVVNEKQIQRMVSLCGASLPRKFTVMMQRFGHSPEAIRDAGIAYAV
DQIVDLVANGVDGIHLYTMNNPLVARRITEAVSGILGR
>A0A0L1J404|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus nomiae NRRL 13137|TrEMBL
MHIKEKLGQNEAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREQEK
WEAAEGGLRYAKDLVRYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFIDWVKKCRAKGINVPIIPGIMPIQTYSAFIRRATWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLTAGINHLHFYTMNLAQATQLVLDELKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIRDLSHLFVSYLEGKLGRLPWSDTPISSEAKTIKPNLIE
LNNRGILTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELITRIESNE
DLTYHAVSKNGELRTNTQDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDNWYLVNIVNNDFHNTYDLFELFKDLNVKDFDVEVTADNADSK
SQEAEATAN
>A0A4Q4U0J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus sp. GIB2|TrEMBL
MEKITDKIAALPADSNYFSLEFFPPKTTMGFANLRDRLDRMARALRPLFVNVTWGAGGST
ATKSLELAEICQRELSLTTCLHLTCTNMSRRMIDTALEDAKALGIRNILALRGDPPRAAE
YQDPNGEPEDAIDENFKWAIDLVRYIRKTHGDYFCIGVAAYPEGHADESHPQGQSLEHDL
PYLVEKTLAGADFIMTQLFFDTEAYERFERILREHPSGAFKTLPIIPGLMPIQSYQMIKR
TTKLSHAKIPDSISARLDAVKKDDEKVKNVGVDILSEIVERVKEIKGRTPGPKGFHFYTL
NLEKAVSFILERTKLIPPSTPEEDEAVADGLAPRVPTVEVNGFTHESPMPTKHRERRESI
ARSDVDASIHELPVPAQDRIRRQSTVGSEPRNRVIVSEGSPSYPEYEATQAEASMLAEPI
NTRANTLAISEGEGTLGREATWDDFPNGRWGDARSPAYGEIDGYGPSLHVTNAQAITLWG
YPKRPEDINDLFVRHLRGELSAIPWSEEELNAETAAIADQLLALNSKGWWTVASQPAVNG
LPSSDPTFGWGPQQGFVFQKAFVEFFLPSAEWRVLAEKLQSAEVQDTVSWYAANAAGDFA
SSDLTGGLAGEAAKEPSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSDEAFGIFAEWAKVY
GKGSESAALLEAARADVWLVNIIHHDYVDSDALWKLLLN
>A0A2N2TXG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-14|TrEMBL
MQRTFSFEFFPPQTPEGMDKLRATRRQLAQLKPAFFSCTFGAGGSTRDRTLETVLEIQAE
GHPAAPHLSCIGSTQENVRAVLARYQDAGIRRIVALRGDLPSGMADPGAFRYANELVEFI
RKETGDWFHIEVAAYPEYHPQARSPRDDLENFRRKVEAGANSAITQYFYNADAYDQFVDQ
AQALGVTLPIVPGIMPIANFSKIARFSDACGTEIPRWMRKKFESFGDDSASVRSFGLDVV
TALCERLLANGAPGLHFYTLNQAGLTSTIWQRLGL
>A0A4Y8RA09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiella endophytica|TrEMBL
MSQINALSNSGIGVSFEFFPPKTEKMEETLWRSIERLAPMQPTFVSVTYGAGGSTRERTH
HTIERMLKETSLVPAAHLTCVDASRDEVDEVVRQYRDTGVKHFVALRGDSQAGVGGEYVA
RPDGYRNAVELVAGLKAIDDFEISVSAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNDVFERYVERVRRAGIYIPIVPGIAPIHDFTKIARFAGATGASIPAWLAARFEGLET
DEQTRSHVAAAFCADQVLDLTKRGFSDFHFYTMNRADLVYSICHILGLRAAAPQSDAAPA
AAA
>A0A4Q5AUY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum subsp. globosum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLTEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAF
IRERRPDMKIYGACYPEKHPQADTLDHDIDNLKRKVDAGVTHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPKRLATLLDRWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWTNVQDLFA
>A0A1H2ESP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas guangdongensis|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLNVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRQLLNTYKDAGIRRIVALRGDLPSGMGMASGELRYANEL
VEFIRDETGAHFHIEVAAYPEVHPQARSFEDDLHNFVRKAQAGADSAITQYFFSADCYFY
FVERARKLGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDLASIQAFG
EQVVTEMCERLLDGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A167BB27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas luteoviolacea NCIMB 1942|TrEMBL
MALSLQEKILDPNQGVYLIGTTPPKLGTDKEQVQTIATKLLNRLHEIEYDGVVIYDIQDE
SSRTDVPRPFPFKQTVDPCEYSQVVSELSKLDVITYKSVAQRDQGEFTQWLHKTKQDFGL
SNLVLVGSPSSKGDIKLSLPDAYQTLRDHQDDFFLGGVTIAERHASKRNEHERLIDKTTQ
GCEFFISQAVYDAQATIDLLTSYVRTCRQKGIEPKRIILTFTPCGGEKTLQFMQWLGISV
PEATKWRMLDSDNTLKESIKICRENLDLILRSCAQLDVPLGLNIESLTNRKEEIDAAINL
YRLLKATMELKLAEKQIA
>A0A853BA51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis endophytica|TrEMBL
MTAEQPATPPGTAQRLLQLLDEATLEVIPLKGAQEQILRTSEKATVAVTCSPKFGLSRTL
EHCTVAANAGRRVVPHLAARMVRDHASLRDFVRQVADLGVTDLYVIGGDAETPAGKYHEA
AELLDDLAAMEHPFTRIGVGCYPEGHPHIDDDRLWEALLRKQSHATYLVSQMCFDATAFT
SWLTQARARGVTLPVRVGVSGPVKLAKLTELSLRIGVGQSLRFLGKQHGLVGNVLMGRTY
DPAPFLRAVLAGQPGRGDDVEGLHVFTFNQVAACQDWLDTQRGARA
>A0A380K9A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gallolyticus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADIIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAREATGDDAFVLGTVGALRGLKQCDLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEAELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNASIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKETNFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDELANLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALKHFKGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A6I4UWC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceibacterium soli|TrEMBL
MSYAAIHPNWEQPRSNMVDGYSLEMTAKELDGLREAAPLIRPNTQIAVTFLPGEEIEQRV
EAAVLVRELGFEPIVHLSARRLQSEEQLDNYLRDITTKAGVKRVFIIAGDPPQAEGPYEN
SLQIIESGLLEKHGIEIVGVGGHPEGHPNNTKEELWDWMERKLAAVRAHGMVPLVVTQFA
FDDDAIIEWIAEMRERGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGVSITN
LIGSAGPDKLVNSLENGLTEKHGRVRLHFYPFGALKASAEWINAHDAKH
>A0A0F4W3H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. IBUN125C|TrEMBL
MIKEFLNNNILICDGAMGTYYSEKTGNDISYCEFGNLNDKNTIRRIHEEYIEAGAKLIRT
NTFSANSKELGVSRKTLKDIIESGIEIAKEAVYNKEVFIGASIGPIRENGADENVVEVLE
EYKFIVDCFLDNNINVFIFETLSNLDYLEEVSTYIKNKKPESFILTQFAVKPDGFTRDGY
SVSKIVGEVKKINTIDSYGFNCGSGPTHALELIKKIDIGDDIVSSLPNAGFPEIIHERTV
YPNNPVYFARKVKEIKKLGVSIIGGCCGTNPSYISKLRDTIDNKPEPGDKIKRYEHETYN
EKNIIKNTFKEKVKNGDFVIAVELSAPVDTDINKIMTGAKVCKDNNIDIVTVPDSPMSKV
RADSVVMSSKIKREIGIEAMPHMCCRDKNTNAIRSSLIGGHIEEIRNILAITGDPISDAS
RIETKSVFNLNSFKLIELINDMNNEVFTSDDIFIGGALNLNVLNKEVEYGRMMKKVERGA
KFFLTQPIYDDSAVEFLKSIKERTDVKILGGILPVVSYRNAMFLNNELPGVTIPQEILNR
FSEDMNREEGQNIGIDIAVSMGKKLKGICDGLYFITPFGRVNMIVDIVNRIKEV
>A0A6F9WVD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp. SVR|TrEMBL
MNVIDRLKTEILTGDGAVGTMLYAKGVSLDSNFEHLNLVRPALVQELADEYVAVGAQVIE
TNTFGANWTKLSAIGLGHKVADINAAGVRIARQAARQGRDVLVAGSVGPLSRGKGDEREL
ESDEMREIFRCQCQALATEGIDLFMLETFSSLKQLMAAIQAAGETGLPVCASMAFLEGGR
SGDGTTVEQFSQSMETAGTDIIGANCGAGPLELANVVRRLAALSTRPIAAYANSGFPEYR
EGRYIYRATPDYFAAMAVEMAEAGATLIGGCCGTTPEHIAAVSRALKTHRPVPRPQPQLT
DVMETGRTIQTGAASFLDEWGRRKIITVELDPPKGMDCSRIIEGSRRLKQAGVDAINLAE
NPLARPRMGNIALGSLIQQQVGIEVIVHITGRDRNLIGMQSDLMGASLMGIRSILAVTGD
PATMGDHAGAKSVFDLHSFTLIKLLSDLNRGVNAIGNPIGRGTGFTIGAAFNPNTSNTLV
QVERLQKKVANGAVFAQTQPVYDPAVFLDALHLTHACNIPVLPGIMPLVSERNAAFLHNE
VPGISIPDPVLARMKGLEKEAGVREGLAIAREFIDATFEAVGGYYLIPPFGKVELALELV
EYIHTRERKSI
>A0A5N9HTG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MTAVEIETSRGLLMAEASRKTAELAKSLSEFNQIDLVCLTDNPGGNPHIRPEVLGQDLLF
RGRDVVINLSCKDYNRNGIESRLWALGSQGFTNVLALSGDYPIGGFKGQAQPVFDIDSVG
LLQLMSEMNEGLPNRMWGSVGREDRLERTNFFAGCAISPFKKFEGELMTQYFKLAMKVRS
GARFAVTQIGYDSRKLSELHTYVNSNNINVPLLGSVFILSAPAARFFNQWGVPGVWVSDE
LKAIANKQAKSKDRGRLFFSELAAKQIAILKGIGYSGVYISGRPQLARIQRIMEIVDSFG
ENDWKSFTSEINFSQQDEFYYYERGENAGLSSDVLNTSYVSSKTKAARAKSRLSVPIKYR
FGKFVHDRVFDKHSLGFKIGRAVYGKIDKNKKLATAAHVFEQAAKVPVYQCRDCGDCSLP
DIAYLCPESQCVKNQRNGPCGGTKAGKCEILDEQCIWLRAYERLKPFGDEEKMLERPVVF
RDGALKNTSAWSNTFLSRDHHGRQSSDDADAGE
>A0A1Z5HQN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calderihabitans maritimus|TrEMBL
MKTESKLEKLLSQGEFVVSGEIGPPKSANGEVVYHHAQMLKDYVDAMNLTDNQTAIVRLS
SIAAGVHVLRAGGEPIIQMTVRDRNRIGLQSDLLGAYSLGIRNVLCLSGDHQSFGNHPSS
KNVHDIDSIQLVKAVKDMRDEKKFICGEEIKKDEPRFFIGAVANPFGDPFEYRVLRLEKK
INAGADFIQTQCIFEMERFERWMEMVRERGLHKRAYIIAGLMPLKSPKAAKYMQKYVSGM
IVPDEIIERMEKAEDPKAEGVEICVEQIKHLQKIEGVAGVHIMAVNWEEIIPTIVEKAGL
LPRPKVS
>A0A1Z5HTZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calderihabitans maritimus|TrEMBL
MSLAEILETKDFVVTVELCPPIGTTIQPLLDQAEKLKSVVDAFNVTDNQRAVTRMSPVAI
CHFLEERGITSICQFTCRDRNRLALQSEMLSAAALGIKNLLLITGDHTLLGDCPEAKPVF
DLDSVQLMATANKLNSGKSLAGTLLNGRTSFYIGGVVNPAPEVREMQIWKLARKVNAGMK
FVQTQAIYDSKEFIKFLEDIRDFNIHVLAGIIPLKSAKMARFLNSKIPGIQVPEHLIQRL
ERAANPKEEGIRIARELIDELRNYCKGVHIMPLGMEEHLPELLGMPAAPSY
>A0A1W5XLQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MOE7|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVKHPDGIAYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWDTDVAHFVD
KCRAGADFAITQMFFYAEDYFRLRERVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPDLAERILAVKDDPAAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A5N9CWA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MHRPIQRIPIQTACLAWISDRPSTNSRGAPVVKITEGCFEATGHTSIICDFSPPRSGDSA
VVTQAQIDADFISVAYNPGRAVRTNSAMLAAGIQQSGKDAVFTLATRDMNKLAVQSLLLG
AQLLGLQNVVVVQGDSFGEQDQARVATVNDYHPTGLISAIVQMNQGQDFKEAKLRAPTDF
CIGGTVDLGRGIEEEAQLAVRKVQAGAEFLITQPIFDVDHVARYRESYAYHAGKAGTLPI
YFGLQVLEQDGVLFSSVPESVRADLEGGRSGVDIALELYQEFQEARLNNVYLMPPIKRGG
ARNYEAAKEFLTSINKI
>A0A1S1DHT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC066F01|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIRLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>J4RPT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. ACP1|TrEMBL
MTLREKHQKGQFTITVELDPPKSSSAQKVFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNEGIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDHGDHPFAQSV
FEVDCMGLLNIAKTLNSGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNGA
HFVQTQPIYDLEQAKRYIDKMSEFNVPIMLGLIPLKSFKMATYLHEKVPGINLTQDILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>C0EZI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum hallii DSM 3353|TrEMBL
MNTMQTNPQDILKTLSLSFEVFPPKKWEDFPGLYETLDELKGLHPEFISCTYGAGGSNSK
KTAEIASHIENELGIRSIAHLTCAALTEDKLLSTIENFKNAGIHSVLALRGDKPFDMSEE
DFANRQYKHPSEIIPILKKAGFRVAAACYPEKHYEAPSMEEDLHWLKHKVEQGADALISQ
LFFDNDAFYRFMDAADQKGITVPIHAGIMPITSAKMINTTINLSGASIPKALSDLIATYG
ENPSDMRKAGIEYAARQINDLAEQGMHYVHIYTMNHSETAKEICGLIK
>A0A5N9G8N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MLLDEGLEPILQITCRDKNRIAIQADLLGASALGITNLLCMRGDNPQAGDHPDATPVFDI
ETIELLEAIGSLRSGTDMMGAQLRGAPELHVGAVCNPGSPDMEGELKRMEEKIAAGAEFF
QTQAVYDSKAFDAFMSEAKAFDIPVLAGMILLKSGDMARNLNANLWGVSVPDGLIRELDD
AEDKGAKCIEIAARTINEISSMCHGVHIMAIGWESRIPKILEGAGLSPG
>A0A1M4WIF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium vrystaatense|TrEMBL
MKITEHIKKANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIEN
IMALRGDAMKGHQYFEPTPGGHASAMDLVHQINDLGRGKYLHNDEEACDELNKFCVGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVTKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEELINEVEKAKNNEAVKQIGVEWAINQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A7Y1SHZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium|TrEMBL
MQRNSEIQNLRKNTRSIANHDADAQKDLNISFEFFPPKNKSMNETLWNTITKLETLNPKF
VSVTYGAGGSTRERTHKTVARIVNETKLRPAAHLTCVGSLKSEIDEIAKDYWDAGVRHIV
ALRGDPESGIGNAYKPIPGGYNYGSDLVAGLKNVAPFEVSVGAYPELHPESQNWDAELDN
LKRKIDAGADRAITQFFFETDTFLRFQDRVLDAGIKIPIVPGLMLQPNFKGLKRMSEMCA
IAVPNWLEALYADLEDDPQARLLVTATTVADLASNLRDQGIQDLHFYTLNKADLAFSVCK
ILGFQSQKKAVA
>R6DTJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:230|TrEMBL
MTVQEYLKEKPLLFDGAMGTYLVEKHPETVKRNCEFMNIEHPEWVQKIHEKYLKAGAVAI
KTNTFSANTVVLQQPVEKVKEMIKKGYQIAQNAIKDFAGERFIFADIGPVPVNEEKDLLE
AYKEIANTFLECGAQNFLFETMESREAIEEIASYIKEKAPGSFIAVSFAASPEGYTRGGF
FVKKLFWDLQQSESIDALGFNCVSGPKHLLDLVQRLDKKKIKKYLTIMPNAGYPTLLGNR
MYYEQSYTYFSNNIEKLLEEGVAMVGGCCGTRPKDIKGVAEMMQQKQDRFVTWIEKRDRK
LVQAAGYKEELESTHIVANKNEHNTFAKKLFAGEKVIVVELDPPIEPDIDFFMEGAARYK
YAGVDAIDIADCPIAKARIDSSILACKVTRELGLTTIPHMTCRDRNINATKALLLGLNVE
GVNNVLTVTGDPVPTAMRDQVKTMFSYNSAMLARHIQSLNEEVFEENPFMVSGALNINAL
QFDSQIRHAKKKIENGVSVLFTQPVLSERGFANLKRAREELDVKILGGIMPVVSYRNACF
MNNEMAGIDVQDTIVSMYQDKNREEGEELAYRISTAIIDKITDYVDGYYLITPFKRVELL
LRIIHYVKNKNNR
>A0A8J5GN86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MSSHFCDEPNTGLWDPTWHLRLRLLFRSPDQPLLPLQIHSSQAILLVRFEPGWEFSVGRL
RLLKKKLIRGGNIDPVPQFETGHVLGVLLASSPLLEQAWTHCLRANAGSASFVIDKSDDA
VFIAFSRAQAAASPSGLGRGFFEPVSLYSITHKLFALLGRGEEDSGGKPQPVLLQAPYEE
EAQCAALCKSDKVCLETIMHLTCMNMPVEKIDHALNTIKANGIQNVLALKGDPPHGQDKF
VQVAGGFACALDLVQHIRAKYGDYFGITVAGYPKAHPDMIQGDEGATLEAYNSDLAYLKR
KTLSVVLKFWKSFSHVKILELCEIFIFWSANS
>A0A7X4LIH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. CAIM 722|TrEMBL
MGYTHASHIDALNQNIAELSDINVSFEFFPPSSEKMEETLWNSVHRLKTLNPSFVSVTYG
ANSGERDRTHSIIKEIKDKTGLVSAPHLTCIDATREELIKIADDYWNNDIRNIVALRGDI
PEGAGQPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLRRKVEVGANRAI
TQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVTNFKQASRFAAQNHVKIPSWMAKQFEG
LDDDPVTRQLVGASQAIDMIRILSREGVKDFHFYTLNRAEMTYALCHTLGIRPTPAA
>A0A7X8VD13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacteraceae bacterium|TrEMBL
MGLLQRALASGEFAVTAELAPPKGTDFSHALQCAELFGDRVHAINVTDFQSSSLKATSLA
MCKALIDIGLEPVLQLTGRDRNRIAIQGEMLSAGFFGVKNLLALTGDHPTVGDNPGAKPV
YDLDSVGILQAATMLANGIDMSGNKLEGHPSFFLGASVTPEYDPIELQLIKMEKKIKAGA
KFFQTQAVYDIQTMENFNEIIKHLNTKILVGIIPLKSAGMAKFMNKNIPGINVPHNLIDR
LKNSTDPVKEGIKIAGELIVELRERNLCHGVHIMAIGAEENVPLILDEAGL
>A0A2Y9K9Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enhydra lutris kenyoni|TrEMBL
MDHPTPKVLPSRSHGPSLGLWTLEADRVRFSVPPSISRNLAMVNEPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQGQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSRLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFAHYLS
GEPNQHGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWVEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPEPEQDTQAL
>A0A1U7ECF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jeotgalibaca sp. PTS2502|TrEMBL
MSTSQSNVSLSFEVFPPNSHVATKKLLGTLQELQDLQPHFISVTCSNRESRIEETTVRIA
DYLQNDLRIPSVAHLPASYLSKEQVTAIINKIEKAGIKRVLALRGDYLDGVVAKTDFVYA
NDLIHYIKTLAPNLEIFGACYPEVHPDAENRVTDIKHLKKKVDAGCNQLISQLFFDNNMF
YQFKEGCELAEINVPILAGIMPIVNRQQTLRLIKASDSHLPKKFLAILEKYEHNPIALRD
AGLAYAIDQIVDLVTQGVAGIHLYTMNQAETARHIHGATQSLFLNN
>A0A0P1GYU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tritonibacter multivorans|TrEMBL
MTDAKTKTPEISFEFFPPQNLEASFRLWDTVQALAPMDPRFVSVTYGAGGTTRELTRDAV
TTLQRNSGLRVAAHLTCVSATKAETLEIAEQYTDAGITDIVALRGDPPKGAKAFEATQDG
FGSSVELIEALAQTGNFILRVGAYPEAHPEASDMQANVDWLKRKFDAGADEALTQFFFEA
ESFFRFRDACAKAGIDTDRITPGILPIENWGGARRFALRCGARVPAWLDEAFAKAQRDGR
SDLLATALCTELCTDLLEDGVNRLHFYTLNRPELTRDVCNALGITPKVRLENVA
>A0A1Y5EVU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cycloclasticus sp. 44_32_T64|TrEMBL
MALESHQPISFEFFPPKTEEGREKLLKVSQTLGQLAPAYFSVTFGAGGSTQQGTINTVLD
LKKQGFSAAPHLSCVGSTKENIRDILANYKQQGIGRIVALRGDIPSGTLDVGEFRYANEL
VRFIREETGDHFHIEVAAYPEIHPQAGSAQIDLANFKQKVEAGANGAITQYFFNFEAYIR
FVEDCDKMGVNVPIVPGIMPITNYSQLARFSDMCGAEIPRWIRKRLEGFADDRESIKAFG
ADVVSELCQSLLDYGCPGLHFYSMNQAEASLLICRNLGIENA
>A0A436RFV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.046.02.1.1|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFVDFGVTRFVALRGDPAAGVGT
SYRPHPDGYANGAELV
>A0A3Q8Z5E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFVDFGVTRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>A0A1E7GW24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium C00003096|TrEMBL
MHILDIFAANPTTFSFEFFPPKTDKAANRLYETIRQLEPLMPHFTSVTYGAGGTTRERTH
ELVMRIHEQTELDPIPHLTCVGSSAEEIKQILTCYAEAGVSNILALAGDPPPEQPNYDRS
KDAFPQAADLVRYIRQFNERGLHPDKRGFGIGVAGFPEGHPGTPNRLLEMDYLKAKVDEG
ADYICSQLFFDNRDFYDFRERCLLAGITVPIIAGVMPIASVAGMKRMADLAGGTRFPAAL
LRSVQRCQEDPEAVRNIGIHWATEQCRDLLDNQVRGIHFYTLNNSDATKLIFLRLGLKTQ
>A0A1H4J2L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor aquibiodomus|TrEMBL
MPQQRFSRQPDVAGKLRVSFEFFPPKTDTMEARLWETVQRLEPLAPSFVSVTYGAGGSTR
ERTARTVRRILDETSLTPAAHMTCVDASREDVDQVVGEFVDMGVKRFVALRGDPSAGVGA
AYRPHPDGYANGAELVGAMKRQGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDHYERYVERARRAGIYIPIVPGILPVHNFTQVANFAGRCGASVPGWLAERFE
GLEDEPQIHALVASAVAAEQVLDLMERGIDDFHFYTMNRADLVYAVCHMIGIRPRPSKGL
EQPAAA
>V6KU47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces roseochromogenus subsp. oscitans DS 12.976|TrEMBL
MNPALTVPPAVGAALLDDFSLEMTGKDVPRLEEAQRSIPRGTRINITFLAGEDLGTRLAA
ARAVKRLGFVPVPHISARRLPSRAALEEFLSGLAADGTAENVFVVGGDPARPEGPYGDAL
AVLRTGLLQHHGVRHIGISGYPEGHPAIADGTLWSALTDKAAAIGAHRFGGDVITQFGFD
VEPVLSWLEAARARGVHLPVRIGVPGPAGVRRLLGYATRFGVATSASVARKYGFSLTNLM
GTTGPDRFLHALAQRYDPERHGAVKVHFYTFGGLRHTAEWITGFRQTVRQAP
>A0A366QQS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella moniliformis|TrEMBL
MSKKLIDEALSDAKALGIRNILALRGDPPRREEYRDPEDSEDDGGQDFNWAIDLVRYIRK
THGDYFCIGVAAYPEGHAEESHPLGQSLEHDLPYLVQKVQAGADFIQTQLFFDIEAYDHF
ETTLREHPSGAFEGIPIIPGLMPIQSYQMIKRTTKLSHAKIPDHLLARLDAVKGDDERVK
MVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLNLEKAVSFILERANLIPDPPENEEAIAV
DELAIPSLQINGSANMRSSSHSRSRQSRRHSSVASDPHNRVIVGDRPAIYPEWEATGQEA
GVRAEAINTRANTLAISEGEGVLGREATWDDFPNGRFGDARSPAYGEIDGYGVSLHMSVT
QAVKLWGYPKKRQDINDLFVKHIQGELSAIPWSEEELRAESSTIQPNLLQLNRKGWWTVA
SQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFFIPTNEWDILKAKLTLPELQDSVCFYAS
NARGDYLSSDSSDHVNGSTEAGPSTNAVTWGVFPGKEIITPTIIEEVSFRAWSEEAFGIW
GEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHDFVERDALWQLLLS
>A0A3C1FI95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriaceae bacterium|TrEMBL
MFGDEATIAELLAEGGRATMSFEFFPPKDDAGTTQLVEAVTALQPLRPDFVSVTYGATGS
SRERTIDATKLIAARTDALTMGHLTCVSQSVADLRGAIDAYAEAGVGHILAVRGDPPGGP
TAAWQRHPEGLDNATELVKLIKESGDFCVAVGAFPDGHPEHHDFELDARILAEKEQAGAE
FAITQLFFDADAYFRLVERVRALGCQLPIIAGIMPVTNISQIERFAGFSGAPLPTAVVSR
LHAVADDPAAVRAVGVEIAVGLCDRLLAGGAPGLQFFTQNRSRATAEILGALRQIPPH
>A0A4R2MGF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax gelatinosus|TrEMBL
MSTTPVSFEFFPPNTPVGADKLRTVVQDLAAVKPEFFSVTYGAGGTTRERTLETVKAIAA
MGHEAAPHLSCVGSTEANIAEILATYREQGIRRIVALRGDLPSGTATAGEFRYASELVEF
IRRTQGDDWFIEVAAYPEYHPQQRYARRDLEHFANKVGAGANSAITQFFFNPDAYFHFVD
EVHKLGVRVPIVPGIMPIHNYARIAQFAARDGIEIPRWVALKMEGFMDDAASVRAFGVEV
VTRLCERLIAGGATALHFYTLNQSALSLEICRKLSLAQAD
>A0A2B4FWM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS059628|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMAPKFIEQGIRLLGGCCGTTPEHIESMKRATLHVTPVIEKDTIQRPKVIH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLMKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHEMKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7X3AG83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Z38|TrEMBL
MALGTASTRTDRARTVRDMLASGKTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSV
TYGAGGSTRAGTVKATERIAADTTLTPVAHLTAVEHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNAVF
PDALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A2V2XQZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurococcaceae archaeon|TrEMBL
MFLNTCPKRMINGPCGGYRDTVCEDERLTCVWIMAYYTAIKRGTVDRMFTLKLDSGFKIN
NYYPIPRRPRGAVEKILDGRVFMVYEYTPKPYSSPLNIPSELRGIASIYDGVDFVDNPGG
YPIPSSLPYASMAKNSYRDMHVSIQLTARNRDRSQIASEILAASLSGIDAIVATTGDLED
SGKGVWDLDAPRIIYLARLILDLGLDHLGRRVGLGGEGMAIACSVNINARPLEPEILKLR
VKKRAGAEIVITQPVFDPEILGRFRRMTKDLLGEEMPMILGIIPIMSRKIASFFQNKVGI
KIPEKISKILSSERIDKEELLKTNIEVIENIAREVAHNAFYVSAFGDHKLGYEIGRTIRR
ALS
>A0A7C8H3Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces marneffei|TrEMBL
MEKITEKIAALPPDSNYFSLEFFPPKTQMGSVNLQARLERMAQALRPLFVTVTWGAGGTT
AAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIRNILALRGDPPRSEE
YNMDGDDDSNKDFTWAIDLVRYIRKIYGNYFCIGVAAYPEGHPGESQTDIQDPEKDLPYL
VEKVQAGADFIMTQLTYDFEAYQKFEDRLRNHPSGAMKTIPIIPGLMPIHGYKILTRVTK
LSAAHIPPAIMSRIEQVRSDDERVKQVGVDIVSEIANQIKALPNPGQRGYHFYTLNLEKS
VTLILESCDLIPPCNDDSAVEDGFAIEQVGSNNQDLKTLVSRRRASSINSGPHNRVIVDK
LHVPTDQQSEHSSRKSITYETLASNAGVPALNPPPRSTQLQISEGIGSLGREATWDDFPN
GRWGDSRSPAFGEIDGYGPSLHVNATVAKELWGFPVTREDIGTLFRKHVSGELYIVPWSE
GGAAEDANLNAETQIIKPQLLQIIEKKNWWTLASQPAVNGVRSDHPVFGWGPPGEGFVFQ
KAFVEFFCPNADYQNKVKPTLLKHGSEEFSWFAINATGHLESSFLLSASSSPKPEDASST
IAADEEPVEVRESKGMAVTWGAFRGREITTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRG
SATERLLNETKNDAWLLCVIGHRYGAGTEPGSEEEKAEMNTLWNVLAGDM
>A0A845BH73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Craterilacuibacter sinensis|TrEMBL
MNKRNFSFEFFPPKTDEGMAKLRNTRAQLAQFKPEFFSVTFGAGGTTREGTLAAVQDIRN
AGLAAAPHLSCIGSTRDNIRAVLNEYREHGIRHIVALRGDMPSGMVEAGEFRYANELVSF
IRAEHGEHFHIEVAAYPEFHPQARSAEEDMANFVRKVEAGANSAMTQYFFNADAYFRFVD
EVQARGVTIPVVPGIMPISNFGQLVRFSDMCGAEVPRWLRLRMQAYMDDSASIRALGLDV
VTELCDRLLSNGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A254Q6N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter aenigmaticus|TrEMBL
MELSVEFFPPKTPEGEAKLHLVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
AETGEWFHIDVAAYPECHPQAKSPATDVDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YDLGVTQPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDTASIRAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLSLNR
>A0A132CCW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. ABCPW 14|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQQ
AGLEAAPHLSCVGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFVRKVKAGANAAITQYFYNADAYFRFVE
DAAKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKLVCERLGL
>A0A258JG47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium 32-34-25|TrEMBL
FLHGELPIANAPDFCVGVAGYPEKHIEAPSLEADLKRLKEKVDAGADYIVTQMFFDNQRY
FRFVEAARAIGITVPIIPGIKPVAVKRHLQLLPQVFWLDMPESLISAIENAKDNAAVRQI
GVEFAVQQSKELIEFGVPCLHYYSMGKSDNIHQIASQLF
>A0A5Q4C1F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum shisoi|TrEMBL
MHIKSMLDETRRTGEPSFSFEYFPPKTAQGVQNLYERMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREQEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDGDNFVRWVGKVRERGINVPIIPGIMPIATYASFIRRAKHMNCKVPDDWMAAL
EPIKNDDVAVREVGKGLVADMCRKIVAAGIHHLHFYTMNLAQATRMVLEELNWMPTSDRP
VKHALPWKQSLAHGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPRSIKDVANIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSTHPVHGWGPANGYVYQKAYLELLVHPDVYAEIVSRVEKNP
DMTYYATTKNGSLKYNATHDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGIDW
AHCFEAGTPSRVLIERIMNEWYLINIVNNDFHQKTALFDMLEGLEVKEYADIPAEPQTNG
AVETNGNSISATAN
>A0A519JVJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MSTPVSLAEARALLLSPLGPVARAGQDASRPRVSFEFFPPKSDEAEANLWKAIQRLAPLN
PAFVSVTYGAGGSTRERTHRTVERILAETDLQPAAHLTCVDASREEVDAVIEGYKAAGVK
HIVALRGDPPGGAGIGGVYQPRADGYANATELTAAI
>A0A427YCP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saitozyma podzolica|TrEMBL
MKITDKLAKAEREGRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGKNA
DLTSSLVEVCQDTIGIECCMHLCCTEMPKEKVEWALKQAKAHGCQNILALRGDPVAGSTT
WKPTPGGFHHAVDLVRFIHEHYPGDFCVAVAGFPQGHPETPDTPEGHHQEMIWLKEKVDA
GADFIFTQMFYDTDIFFDWVRRVRAAGITVPIVPGIMPIQNWEKFQTWVKREKIVVPPHF
YDALLPIKGDDEKVRAVGTKLVGQMCRTLLENEDAGIKGLHIYTLNLEKGARMLLRELGF
EGRREQIAPLPWRPSLTPHRRTETIRPIFWANRVKSYLSRTDDWDEFPNGRWGDSRSPAY
GDLDGYPVSIGIASTEAYSLWGHPTTFADISALFARFCRGDLVKLPWSSQPPASETSVIT
DQLAKMNELGYLTINSQPAVDGVPSDDRVHGWGPAGGYVYQKAYLEFFVSPSLLSALIRR
IERDPRITYFAVNKGGDLRTNNHSEGPNAVTWGVFPGKEIVQPTIVEAISFIAWKDEAFE
LGLQWAGLYPEGSPSRVLIEEVMSTSYLVNIVANDFKDGTSIFAPFVLDQAVPAAANGVN
GVNGSHAVAEKANGVLESVANGVKSAVEVVKGASASVNGH
>G0T0T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosporidium toruloides (strain ATCC 204091 / IIP 30 / MTCC 1151)|TrEMBL
MVKISDKIKKAEREGRPWWSFEFFPPKTPEGWVNLYDRIERMQQLGPIFVDITWGAGGST
SEATTNFVKTAHSELGLETCMHLTCTNMPVEMVDKALKATYDSGCRNILALRGDPPRGVE
EWKPTEGGFNHAIDLVKHIRKNYGDYFCIGVAGFPEGHPQSESPEAEIRHFKKKVDAGAD
IVFTQMFYDAEVFIDWGRRLRAAGITIPIVPGIMPIQTFAAFKRRTDFAGTIVPKELWDL
LEPIKDDDAKVREVGTKYVADMCRKILNADLGIHGIHCYTMNLSRGTEMLLEEMQFVPTA
DRVKPLPWRLSLTQKRRAETTRPIFWSNRQKSYITRTRDWDEFPNGRWGDASSPAFGDVD
ALLLALPHKPQDAIKLWGKPHSLGNITALFARFCRGDLKSLPWSDQPAAKETTRIAEQLA
RINELGFLTINSQPRVDGAPSEDPAVGWGPIRGYVYQKAYLEFFCPPELVEPLLELLGDT
PSVTYHAVNKQGDFRSNTAPGPNAVTWGVFPGAEVIQPTVVDSTAFQAWKDEAYELGWQW
AQLYKETAPETYEVISRIFSEFHLVNIVFNDYRNTDEDAIFKPFFELAHRKGLSVANGH
>A0A844A8B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium fredii|TrEMBL
MSPDINPFDPSAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDTIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHEATPTETLVAERLGHLREGIEENQQQLAEAAAH
HPH
>A0A7S3VQX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dunaliella tertiolecta|TrEMBL
MKVIDKINQKVAAGQHFFSFEFFPPKTEEGVDALWERMERMVAHGPIFCDITWGAGGSTA
NATLDIAAKMQNMVNIETMMHLTCTNMPAESLDTALKKVREAGLQNILALRGDPPKGHDK
FVTVEGGFSCALDLVKYIRKTHGDYFGICVAGYPEAHPETLTDDDEAANEKAYTESLSYL
KAKVDAGGQLIITQLFYDCDRFLKFVKDCRAVGIQCPILPGIMPIMTYGGFKRMTGFCKV
KVPQEINDIVEANKDNEEAIKAYGVELGAKMCKYLLANGIPGLHMYSLNMEKSALAILER
VGFIDNSKVPRPMPWGFVPINSCGLRRNESVRPVFWSNRPKSYVWRTKDSQAFPTSKWEG
AMARLTFSEDPAFMQLHSCSEGRRAKSQEVWGTPTTVADVQKVFSQFYKNEMGMLPWSES
STQFAIKNGTALSSLEAAQGAVLALVDATLLPINVLLRKFAVPSETPVLGWGPAGGQVYQ
KGHVEFFASPEAFQTLLPKLQSQPSLTYMATNAAGADVSTNLQDGAVNAVSWGTFPGKEV
VQAVVEDVASFKVWAKEAFELWKSDWASCYESGSKSRELLEGLCSSWYLVSVTDNQYTKG
DYLPSILA
>A0A1B3XPZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peribacillus muralis|TrEMBL
MNFRKELKERMLVGEGAMGTLLYSYGIDQCYEELNCTNPDQIESIHRAYLEAGADILQSN
TYGANFNKLKRHGLEDEVSKINRQGVILAKKAAKGKAYVFGTIGAQRSIRKSDLSMEEIK
RGFREQLYSLLMENPDGILLETYYDLEELETVLQIVKKETELPIIANVSMHELGNLQNGL
HLNDAFQKLEQLGADVVGVNCRLGPHHMIRSLEEVNLPKHASIAIYPNASLPDYVDGRLV
YKAVPEYFGSSALDLRKQGATIIGGCCGTTPLHIQAVKKAVGSLAPVNEKFTKPRQIEII
EINDREGELPLYEKAKTERTILVELDPPKKLGIENFMIGAKALKSAGVDSITLADNSLAS
PRISNEALANLLKTQLNVKPMVHITCRDRNLIGLQSHLMGLQTVGLNEILIITGDPSKIG
DFPGATSVYDLSSFDLISMVKQFNEGLSYSGQSLGQRANFKIAAAFNPNVKYLDKAVQRI
EKKIACGAHSFLTQPIYSVQQMEEVHEATKHLETPIFIGIMPLTSTRNAEFIHNEIPGIK
LPDNVRRAMALAGNDPVKARMEGVNIARELVDAARDKFKGIYLITPFLRYEMTAELTKYI
KKIDSKQTSEVAVHE
>A0A3N0ZRB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes/Chlorobi group bacterium ChocPot_Mid|TrEMBL
MITQKDFLKELNSKPLLFDGAMGTEIYKRGVFINKCYDELNLTNPNLIKQIHIDYKKAGA
DVIETNTFGANRYKLKNHLLQDKVYEINFQAASIALEVADNEIYVAGAIGPLGVQMEPLG
PLAKEEAVEAFEEQAKALLEGGVNLFVLETFIYPEELNQAIIAVRKICDLPIIAMMTIDE
AGNSLTGASPEVFVKQLESYGADVIGVNCTVGPHRMLNWLEKSRGFTNLPLAVMPNAGKP
RNIDGRNIYLTSPEYLGEYAKHFIQTGANIIGGCCGTSPEHIKAMRNSLNAIRPNYRKIN
ITSIEKIILPDVKVIEQENKSRLASRVKNGYFIKLVELLAPHGVSATSEIDKARNLYYQG
IDAINIPDGPRASARMSALSLALQIQREVGIEAVLHYVCRDRNVIGIQSDLLGAYALGIK
NILAITGDPPKLGNYPDATGVFDVDSIGLVNILNRLNHGLDIAGNPIGKPSAFFVGVGAN
PGAINLDEEIKRLEWKVDAGAEFIITQPIFDIKILENFIKRIEHIRRPLIAGLWPLTSIR
NAEFMNNEVPGCNVPENIMNRLRKVEDSKEKSLQEGISIARETLHEMLGEIQGIQISAPF
GRIQSVFDVLDGFVFK
>A0A3A9FF58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium 1XD42-8|TrEMBL
KEKTLFSLEVFPPKKDSDFPAIYELLDTLKHLHPHFISVTYGAGGSHSKKTVDIASYIQN
SCNIEALAHMTCVGCNDTSLLSICQELKTANVHHILALRGDRPKDMTDEQFHRKTFSHAS
NMVAFLKSNTDFQIAGACYPEKHFEAKSMDSDIMHLKEKCDAGVDFLISQLFFDNDLFYY
FLEKAKKNNIALPISAGIMPITTARQLTTTVSLSGSSVPKKLSDMIAKYEGQEEDLRKAG
IEYAIHQIQDLLHHGVDGIHLYTMNKSVTASEIFFAVR
>A0A1F1DFA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC066G02|TrEMBL
MTTVHPALSFELFPPRSHASCESLLHTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSNAE
LHRIGVDYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEY
A
>A0A4R1KS97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella wandonensis|TrEMBL
MKVTEHIKNANGITQFSFEILPPLKGQNIQSIFNNIDPLMEFNPPFIDVTYHREEYTYKD
AGNGLLKKQVVKKRPGTVGICAAIQNKYGVDAVPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKTETYFKPEKDGHNYASELVHQIAGMNKGIYLDNELENCSSTNFCIGVGAY
PEKHMEAPSLDSDIHFLKKKIKNGAEYIVTQMFFDNQKYFDFIDKCRLEGITVPIIPGLK
PIATKKQLNLIPHRFHVDLPEELVIEIVKCKDNSAVKQVGIEWCIKQSKELQKAGIPVLH
YYSMGKSNNIQQVAKAVF
>A0A0A7PET2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis fribergensis|TrEMBL
MTSNLNSLAEARRAAASPLFANLEGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASRAEINEVAEAYWEAGVRHIVA
LRGDVPGGEPYRAHPDGYANAIELVAGLKAIAPFDISVAAYPETHPDADCAESDLDNLKR
KLDAGATRAITQFFFSPDSFLRFRDTAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMVSLFDGLDDHPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVLTAKDQAA
>A0A2A4FWD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizorhabdus dicambivorans|TrEMBL
MKLALAAQDSPVLDLVRSFSLEMTAKDIDSLSEAAPLIPAGTPISVTYLPGEEMPARVAA
AKAVKALGFVPVPHISARRVLSRDDLADFLAILDDQVGIERAFVIAGDPPAPMGPFEDAL
AVIRSGMLDAAGIRTVGISGYPEGHPDIDKPKLARAMQDKLAALAEQGKEAEIMTQFAFD
ADAILVWLERIRQDGVVAPVRLGVPGPASVKKLVRFAARCGVGASAKVMLKYGTSITKLF
NTAGPERLIEDLAARLDPARHGQVMLHFYPFGALLDTARFIDTNYPAAGR
>A0A7Y6P5J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus licheniformis|TrEMBL
MGFLEDIKSKTLIADGAMGTLLYSYGIDRCFEELNISKPEEVRRVHKAYVQAGADIIQTN
TYGANFIKLSRYGLEDETKQINEKAVRLARSAAGSAYVLGTLGGIRTFNKNSYSLEDIKR
SFREQLYLLLNEQPDGLLLETYYDLEEAREVLKIARKETELPIILNVSMHEEGVLQDGTP
LADGLKQLASLGADVVGINCRLGPYHMIRALEEVPLLEDAYLSVYPNSSLPSLVEGRLVY
ETDDEYFRESAEEFRNQGARIIGGCCGTTPNHIRAMAEAVKGLPPVTEKRVKIRKKAALA
VQNERTEPALDDLAKQKRSIIVELDPPKQLNFEKFLNAAEELKSAGIDALTLADNSLATP
RISNVACGALLKQRLDMRSLIHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRLE
KKIACGADYFISQPVYSEEQLIKIHEETRHLETPIYIGVMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGNDKQKQAEEGLAIARSLLDAACDLFNGIYLITPFLRSDLTAELTAYIH
QKEKEKTNV
>A0A3E2T2N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MMNIRELLQTRPLLFDGAMGTYYKAAPGVECEQANLTDPAGVLAVHREYLAAGADAVKTN
TFSLPRLAAAHTPGWEQLAQAGWQLAVQAAEETGAAVFADLGPAPDTEAVPAGQVYTAVA
KQFAALGARNFLFETLSSDAGLLDAVGAIKAEVPDAFVLVSFAVLPDGYTREGMYCKDLA
RRMQESGIVDAVGLNCVSAPGAMRTLAKQLGGTLPLSVMPNAGYPVVTRTQVKYQGRPEY
FARELGRLAAEGTVQILGGCCGTTPAHIAALRAELDRLPVVEKTAPAEEFSAVKEQTVEN
EDAFLRKLNAGEKVIAIELDSPRNADLTGYLEGAKKLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGLCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPGPMTVFGALNLNARNFDVELRRAKEKLENGMSGFL
TQPVLSARAVENLKKSRETLGADAKILAGIMPVVSQRNAIFMENEINGIHVEDWIIEKFA
GLDRAQGEELGLAISLEMAKAALPYADGLYLMTPFNRVALMERLIGRLKQEVLGAY
>A0A4R0DU91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter terrestris|TrEMBL
MSKLFQYLSQKQFCVVVEYLSSHKFDSVAQEIAGFPTVIALADRVHSDDDPSPLQIAQQC
PIDIEKLIHFSGKARDIADFEQFLHQAKTQGINNLLLLTGDKLKQHQSGTKNIERTRYLE
SVNAVMAAKHKGGFCIGVAFNPFKYAEAERDAQYFKLHKKIKAGADFIISQLGYDLDALK
QAQLFLKEHQYRQSIMTCIMPLSLGRAKYMVKHQVAGTVITQHMLNVLEQEKQQGKTNHI
YLRCALQILICQHLGFGGVHLSACYKPEDQMLLAKYIEKYRHLSLVECESLWNDHWQIKT
GKEFHPVLENDSISVTSIQILKYRNLKFMHDALFQSSVARGIGFFIFKAQFWNRSLSMKA
LLKTEFISKHHIVGCESCGLCRLADTLYICPETCPKGLANGPCGGTYLDRCEFGDRECIH
SVKARLAKAVKQTEILKNKLIPSVPIELRGTSSWKNWYLMKDA
>A0A5N5P8U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coniochaeta sp. 2T2.1|TrEMBL
MDKITDKIAALPPGQGYFSLEFFPPKTAMGFSNLRDRLDRMSRALRPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRKLIDQALQDAKALGIRNILALRGDPPRRSE
YRELNDPEPEDGEEEFVWAVDLVKYIRKNHGDYFCIGVAGYPEGHADESHPLGQSLEHDL
PYLVEKVAAGADFIMTQLFFEIKAYDHFETTLRQHPSGVFKDIVIIPGLMPIQSYQMIKR
TTKLSHAQMPDVIMERLDSVKGDDERVKMVGVDIVAELVEKIREIKSRTSSGPKGFHFYT
LNLEKAVSFIVERTNLIPPSTPFEDESAISDDLPPTSIPELHVNGSSSSQILSLKNLSRR
QSSVGSDPRNRVIVSGRSGVSNPDYEATALDAAIPAEPINTRANTLAISEGEGVLGREAT
WDDFPNGRWGDARSPAYGQIDGYGVSLHVSVAQAINLWGTPTTPEEINKLFIRHLRGELS
AIPWSEEGFNAETAAIRDQLVKLNGRGWWTLASQPAVNGLKSNDETFGWGPMNGFVFQKA
FVEFFIPAADWAALEKKLTRPGMRDTVCFYAINARGDFVSSDTLPTTNGEAGSGDAEEKA
EDGAREPSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFSIWGEWAKVYGRGSESQKL
LDRIREESWLVNVIHHDFVDKDGLWDLLLKD
>A0A7X8BXX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium|TrEMBL
MKVTEHLERNDKPLFSFEIIPPARGSSGQYIIEIVEQLKQFNPPFIDVTSHSAEAYYEEM
PDGSIKRRIKRKRPGTIGICGVIQNRFNIDTVAHILVNGFSREETEDALIELNFLGIHNV
LALRGDETNYAKPLNNNKSSNTYAIDLVRQINDLKKGIYLDEIINSSPLNFCIGVAGYPE
KHFEAPNMKTDIHYLKQKIDAGAEFITTQMFFDNQKFFEFTDLCREEGITVPIIPGIKIL
NHKRHLKSIPKNFHVNLPDALVDEVMKNPELAGEIGIEWAIQQCQELLDHGINCIHFYVM
NDTASAIKVIEHLKY
>A0A173TJL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MLDVRKLLTRRPLLFDGGMGTYYKTKPGQECEQANLTDPEGILAVHRAYLAAGADAIKTN
TFSLPRLAAAQQPGWEQLADAGWQLAAKAAGETGAAVFADLGPAPDTESNPAEQVYLAVA
KRFALLGARNFLFETLSAEDGVLEAVRALKQTVPEAFVLVSFAVLPDGYTREGRYCAELV
RRMAQSGVVDAVGLNCVSAPGAMRALVQQLGDAGLPLSVMPNAGYPVVARAQVRYQGKPE
YFARELSRLASEGVRILGGCCGTTPQHIAALRTALDALPDTLPAAPAAKPAEAAKPVVEM
DDAFLRKLRAGQRVIAVELDSPKDADLTAYLEGARRLQAAGARRLQAAGADLLTIADCPI
ARARMDSSLVACRVHRELGMNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIP
TAERDEVKNVYQFNSRKLAQYIVSLAGEGREMPSPITVFGALNLNARNFEVELRRAAEKL
ENGMSGFLTQPVLSAQAVENLKKARETLGEQAKILAGILPVVSQRNAIFMENEVNGIHVD
EAIIQKFEELDRAAGEELGLEVSVQAAKAAAPYADGFYLMTPFNRVALMERLIARLRTEV
TD
>A0A832AJU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spartobacteria bacterium|TrEMBL
MPGRPSRTLSAGASNDLSSKEHFAEPVISQINSKSNKSLGPKVAPGGYAAIPAEPSRNLS
ITFIGSGQYRGCFRKSDGLSTQRGLLMVSHDMSAPSFREAITSGKFVYGAELVTTRGIPE
PGDRPKLVELGEQLLADPRIAWVSITDNPGGNPMLPPDWLANRLAEQRTRVVVHLTCKDL
NRNGLESVASRYAAEGFDHILALTGDYPVTGYGGLARPVFDLDSVSLIALLKAMNDGLEV
TRPAGKVERLPRTNFFIGCAVSPFKRQERELMPQYFKLARKIHCGAQWVISQLGYDMRKF
YEIKLFLQWAQVSAPVIGNVYLLNKTVAKMFHENKIPGCVVSRSLYEQVEKYAAGPDKGR
SFFLELAAKQLAVFKGLGFAAGYLGGIHKAETFFQVIERAERFGENDWKEFAKEIQYPQE
NEFYLFEADPATGLGDITQLNRDYLASLKNPPKPAEVTVGYRLTRQIHEAAFTPGKGLFP
QLEKVYAKLEANGDNLALRALNRIERVSKEMSFGCKDCGDCSLPETAYLCPRKACSKTGR
NGPCGGSHDGRCELDDKECLWARAYDRLKYYGEHEHMLDGPAVFYNASLEGTSSWANLFR
GRDHHHATTPESKPKE
>A0A1Q9GU41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium damsela subsp. piscicida|TrEMBL
MQPITNYQALSLQDSELRVRYNDVTRGVYFIGTTPPKTSTELSDVDGIADKLVDRIKDFA
FDGLIVYDIQDEGSRISKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSEPEVFN
QWLNEAWDQYQVRDIVLVGSPSTQNQVSLPLHEAYKTIADNEHPFFTGGIMIAERHAKKG
NEHQRLIEKYQQGCNFFISQAIYDTQATIDLLTRYAIECQEKGLKPQRIILTFSPCGSAK
TLEFIEWLGVSVPEATSLRILNADNPLHESIKMCCNSLNQILEAVVEYDLPLGLNIESLT
NRKEEIEGSILLYKLLRSTMDMYLAQHEFRKQQGLKKAF
>A0A8D3CPJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scophthalmus maximus|TrEMBL
MVNQAPRGEGSWSDSSGASNSGGESSKESSRSSTPVLDADRSDRLRDKMRRRMESADRWF
SLEFFPPRTTSGAVNLLSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYC
GLESVLHLTCCNQTREIITGHLAKAKHLGLKNIMALRGDPVGADWEEEDGGFNYAIDLVK
HIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVITQLFFRSDTFLKFL
DDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITNVIEPIKDNDAAIRNYGIH
QAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVE
DVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLHM
WGEELMKEESVFEVFTCYITAQPNCSGQKVMCLPWNDEPLAPETNLMKDELEKVNRRGVL
TINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHI
VNVHGRNLTNALDFQPNAVTWGIFPGREIVQPTVVDPVSFMFWKRFYKMKVKEWIMMYTK
CLPNLLNSLRQVSFSPTSNFWKMISPHQ
>A0A735Q313|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 42:z:1,5|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRGELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7Z1AWE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola xinjiangensis|TrEMBL
MTSVVERIPGDRPVFSVEFMPPRDDADERRLWNAIRSLEGLDPAFVSVTYGAGGSNRDRT
IRTTGRVVKETTLVSMAHLTAVDHSVAELRNVIGWYASLGIRNVLALRGDPPGDVMGEWV
RHPEGLEYAEDLVRLVRELGDFCVGVSAFPYGHPRSADLDTDTEYLVRKLAAGADFAIAQ
LFFEAEDFLRMRDRVAARGCDALLLPGVMPLTTPKILSKTVELSGAPVPASIADRLEPLA
DDPAAFRAMGMDVTAEVSERLLAEGVPGLHFYTFNRAKATKEMVDRLGLVPSAPPASAVG
>A0A845ABP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania algicida|TrEMBL
MSTGLDPQSEAQRALDGPLFSGLPGDIEVSFEFFPPKTDKMGETLWRSVETLAPLAPRFA
SVTYGAGGSTRARTHDQVVRIQNEAGIPAAAHLTCVEATREEVDEVARHYWEAGIRHIVA
LRGDPPDGASRYTPHPGGYANAAELIAGLKNVADFEISVAAYPECHPDSPDAQADLDNLK
RKFDAGATRAITQFFFEPDCFFAFRDRAAGAGISGEIVPGVMPVMSFAAVQRMAGLCGTA
IPPWMEGLFEGLDERPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHLL
GLRPKEHG
>A0A562Q7X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus nanhaiisediminis|TrEMBL
MNLLDQLASKILIGDGAMGTFLYEQGVDQCFEEINVTDPEKILRAHRQYVEAGADVIQTN
TYAANGLKLEKYGLKDDVKRLNQAAVKLARQAAGDGAFVVGTIGGVRRFQLEEWSLREIE
TAFSVQMNDILSEGVDGLLLETFYDLEEAKMAASLARKWTDLPIIVNLSLGEVGVMNGGV
PVSSALDQLVAVGANIVGLNCRMGPFHMLRSFETIPLPKQAYLSAYPNASLPDYRDGRVF
YQSNAEYFKAMGEKFIYEGVRLLGGCCGTTPEHIAAFAEVKKNMSPIVSKTVRPIINHVR
ESIDVARKQTPLPDIVKERRSVIVELDPPKKLSTTRFMEGARVLKEAGVDAVTMADNSLA
SPRVDNLALGAMVKEQVGARPLIHVTCRDRNLIGLQSHLMGLNALGIDDILAITGDPTKI
GDFPGATSVYDVSSFQLISLIKQLNEGLSFSGKELGQKANFSVAAAFNPNVRHLDKAVKR
MEKKIDSGADYFMTQPIYSAEQIEALYHETKHIDKPIYIGIMPLTGTRNAEFLHNEVPGI
KLTDDIRAAMAACGDDRVASTREGIQIAKSLIDTALSFFNGIYLITPFLRYEMTVELTEY
IQEQKVTIGLKK
>A0A6I9RDD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elaeis guineensis var. tenera|TrEMBL
MKVIDKIAGDHDGPVVFSFEFFTPKLSGDAEARARASDAFVAKVANMAAHGAAFCDITWR
PRDADSTLALAGRMQREVGVETIMHLTCLGMPLDRIDHAISAVRAAGVQNVLALRGDPPL
GTADAALSAEEAAPGGPACALDLVEHIRSKHGDYFGIAVAGYPEAHPDKIPDGSEVATVE
GYESDLEYLKKKVEAGADLIVTQLFFDVDIFLKFVGDCRRVGIDCPIVPGILPIATYRNF
QRMTETCKTKVPPEVRAAVEARKGDEAALAAYGVELATDMCRKILEKGIRELHFYTMNRE
EPALTVLRNLGLVAVGGKAVPKSLGENQNGEKAELEKKPANGSQ
>B2I856|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylella fastidiosa (strain M23)|TrEMBL
MIPISFEFYPPKNDDQRAQLDRTANRLRAFAPEYVSCTFGAGGSTLSYTSETVRHLSQHH
GFDAAPHLSCVGGSRQEIRELLKLYRAIGCQRIVALRGDLPSGMGHPGDLRYAADLITFI
RAEHGDHFHLEIGAYPETHPQASNTLNDLHYFKAKVDAGADAAITQYFYNPDAYFHFVDA
VQRLGVTIPIVAGVMPISNFDQLRHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVV
TALCERLIAGGAPGLHFYTLNLAKPSTQVLQRLGY
>A0A5C7WB59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niabella sp|TrEMBL
MKVIEHINKAKEKNETLISFEILPPLKGKGIDALYDHLNPLMAFKPAFINVTYHRSEHEF
KQNPDGSFKKVTIRKRPGTESICAAIMNKYDVDTVPHLICGGFSVTETEDALINLKYLGI
DNVLVLRGDAAKNETAFIPEPDGHRFAIDLLKQVVNLNNGIYLEEELINSQKTAFCIGIA
GYPEKHFEAPNMQTDLSYLKAKVDAGADYIVTQMFFDNAKYYAFVENCRAAGITVPIIPG
LKPVYTKKQMTSLPKTFSIDLPTDLSNEIAKCKTNTDVEKIGEDWLLEQSRDLKKNGVPC
LHYYTLGKPHIVANVINRM
>A0A7C6TNA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MRIVDLFDGKKNRLSFEVFPPKRGMPLEESKEIIKEMAALNPDFISVTYGALGNNSDNNV
LVAKEVSDNGILPLAHMTCINSTKDKVEKELEILKANGIKNILALRGDRPKDGSEVKSDF
TYASDLIEFIKKKGDFCVGGACYPEGHPESLGVEKDIDNLKKKVDAGCDFFVTQMFFDNN
ILYNFMYRLLRAKIDIPVLAGIMPVTNNRQIKGIIEISRTMLPAKFKAIVEKFGDNEKAM
TQAGIVYALGQIIDLIANGFNYIHLYTLNKSSIAKAITEALSDII
>A0A7C4YJZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidia bacterium|TrEMBL
MKVIDHINQAKDTLLSFEVLPPLKGKGIGALYKHLDPLMEFKPSFINVTYHRSEHVFKKR
ADGTFEKVVVRKRPGTESICAAIMNKYNVDTVPHLICGGFGINETEDALINLHYLGIDNV
LVLRGDAAKNETSFEPEPGGHKYAIELLQQVVNLNSGIYLEEELKDTHKTKFCIGVAGYP
EKHFEAPNMDTDLMHLKNKVDAGADYIITQMFFDNAKYYAFVDACRAIGITVPIIPGLKP
VYTKKQLTVLPKTFHIDLPTDLSNEILRCKTDEDVEKVGAEWLLMQSKDLKKNGVPVLHY
YTLGRPQVVANVVKDI
>A0A7Y6QKD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. BJB1822|TrEMBL
MASHNFSIEFFPPKTAEGAEKLRATRAKLSELHPKYFSVTFGAGGSTQRGTLDTVLEIMA
AGEEAAPHLSCVGGTRESIRAILNEYKAHGIKRLVALRGDLPSGYGAAGEFRYANELVEF
VRQETGDWFHIEVAAYPEVHPQARSPQDDLQAFARKVNAGANAAITQYFYNADAYFQFVE
QAQKAGVTVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTQLCERLLQGGAPGLHFYSMNQAAATTALWQRLVKD
>A0A7X4YRF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sacheonensis|TrEMBL
MKPDLREALQARILTGDGAMGTYLYGMGFPVGVSYEEFNLLRPDVITDVHRRYYEAGARI
IETNTFSANLASLTHYGLDSEVEAINRAGVQIARGAVGSDAYVVGAVGSIRAGKRKNISV
AQLDDLFRQQINALLTAGVDGIMLETFYDLEEALLALRIVRSLSETPVICQFAVEKEAVT
LDGKPIASAFESLRLEGADVVGFNCRSGPNGILRAIDSINAEVKLPLSVFPNAGIPDYVD
GKYQYTSTPEYFAESARKFADRGARIIGGCCGTTPEHVAAIAAALDGYLPRPVDPSELLQ
PYSERIIVRDERPAATEPTIVDLVKERHTVIVELDPPRDLAIQKFIEGAKALKAIKADAV
TMADNSLAVTRMSNIALASLVQQQVGIRPLVHIACRDRNLIGTQSHMMGLDALGIDHVLA
VTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGVAFSGKALKQKANFITGAAFNPNVK
YLDKAIARLEKKIETGADYIMTQPVYDKELIVRIAETTKHLQVPIFIGIMPLASGRNAEY
LHNEVPGIQLSDEVRKRMAGLEGEAGRAEGVRIAEELLDTAMEYFNGIYLITPFMFYDMT
VKLTDYVWQKTGSLTR
>A0A7C6MVJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MIRDYLRKHVLIMDGAMGTYYSQTTNRYDVPPELANINHPETIEDIHRQYISAGAKLIRT
NTFSANSIVLNMSRSQVKDIITAGVQIANRAAAEKDVFLGASIGPVPDSIDNIDTSPRAV
LEEYRFISDVFLDLGVGIFIFETFNDFTYVKDIVKYIKQRDESVFISVQFATTPEGFTRK
GISNRHVIDQVKACREVDAYGFNCGVGPTHLYNLLKEIDFKDDIIVAAPNAGYPEIIRER
TVYINNPNYFAEKMEEISRLGAKILGGCCGTTPSHIRKMSQLIKSRRHVQPKEWHRIEKP
VASLRKKRPNNFAEKLKNNEFVIAVELDPPFDANIERIMENAHICKQNGVDIITVADSPM
GRARVDSIMMAAKIKREVGIEVLPHICCRDKNLNALKAGLLAGYMENIRNVLAVTGDPVA
AAEKSNIKPVFNLNSLSLTEFLNTMNHEVFKEDPVNIGGALNLNVCNPRAELERAFKKME
KGATFFLTQPIFDDKVIEFLSHIQKCERIKILGGIMPLVSYRNARFLNNEVAGIKIPDHI
INKFHNDMTREEGERLGIEISVDIAQRIKDKVDGFYFITPFNRVHLIMEIIKRLKQLAAV
K
>A0A3D4QU69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKLIDIIRSEKPTLSLEVFPPKNNAAYASIEAAVEEIASLSPSFMSVTYGAGGGTSDYTV
SIAAGVQKRHKLPVLAHLTCINSTRAGVRRQLDLMRESGIQNVMALRGDLEPGRKADESW
DYQFASQLVKEVKEYGGFCIGGACYPEVHPESKNQREDIYYLKQKTDAGCDFLTTQMYFD
NNIFYNFLYKIRDAGISIPVIPGIMPVTNVKQIRRINTLSGAMIPQRLRYILDRFGDNPA
TMKQAGIAYAANQIVDLFANGISSVHVYSMNNPSVARSILNNLSEILK
>A0A0H5NPL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia farcinica|TrEMBL
MVQSLRAHAGRSVPFSVEFNPPRDAAGEARLWRAVREFERMHPAFVSMTYGAGGSTKDRT
VRVTGQLAQETTLLPVAHLTAVGHSVAELRSLVGAYADSGIRNILVLRGDPPGDPLGEWH
KHPEGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLATDTAFLAAKLRAGAEYSITQ
MFFEVEHYLRLRDRLAALDPAEGAKPIIPELMPITSLRTVTRAEELCGRPLPAAVLDRLR
RAAGDGPEEDRAAVREVGIEIATEMAQRLIDEGAPCLHFITLNFAKATSEVLTNLGYGVT
AAPVRA
>A0A3D2KKI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
RDRNRIAIQSDILGAASLGVRNILCLAGDHQTFGNHPGARNVHDIDSLQMVQMVRAMRDE
KKFQCGDQIKSHEPRMFVGAAANPFGDPFEFRVRRLAKKIAAGAEFIQTQCIFDMDRFEK
WMRMVRDEGLDEKVFILAGITPVKSDKALKYIRTVPGMKVPDELIKRMEGAADKKAEGVN
IAVEMIQRLKEMKGVHGVHIMAIAWESIVPEIVERAGLYPRPEVEVEEPAEAEVAVG
>B0V4J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain AYE)|TrEMBL
MISALPMSHLSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAP
LEASKSYPDSIEKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQ
PRSRYLESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKVKAGADFIITQLG
YDIEALKQAKSFLTKHNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQ
VGHTDRVYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWS
SLWQVTTSKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWE
NSVVAKALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEF
GDRECIHSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A7C1XRM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MLVEKIKSRESGIIVYGITPPKKATSVEKIAEISSRQVQRIQSLKIDGLILYDIQDEKSR
TSEERPFPFMETLDAFCYSKEYLRSLPIPKVIYRSVGKYSTAELSQFLKSASPKDTLTVF
VGSPSKSQSVTLSMNDAYKLKAETGSNLLLGGVTIPERHQSKGDEHIRVFDKISQGCTFF
VSQGVYDVNASKDFLSEYYYYGQEHDIPLVPILFTLTPCGSLKTLQFMKWLGISIPKWLE
NELTHSNDILQKSLDFSEQSWLELKNFADKKGIPVGCNIESVAIRKIEVDASIELVQRIS
RSLMSGQAK
>A0A433XQA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus zeisoli|TrEMBL
MKPELELRARLSREVLIGDGAMGTYLYQLGFPVGISFEELNLIRPEVIGDIHRQYSDAGA
QVLETNTFSANYYKLSKFGLESKVEEINRAAVRIARQAAGENKYVIGTVGSIRGGKRINV
SNKELRRYYEQQISALLEEQVDGILLETFFDLDEMRIAQDIVRKSSDTPVICQFAVDDIG
RTTDGYSIIDAFSILRQEGADVLGFNCHSGPKGIMGVMSRLNGPLDLPLSVYPNAGLADY
VDGEYIYGATPEYFGQSAISFADLGARLIGGCCGTTPDHIAAVAAALKNYTPVSLPETSL
LSHESVPVIVAEHAAEEREVPGGRPEGPSIVDLVKERHTIIVELDPPRDLDITKFMEGAS
ALKEVGVDALTLADNSLAVTRMSNMALGHLVLTETGLRPLIHIACRDRNLIGTQSHLMGF
DALGIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKANFV
VGAAFNPNVKHLDKAVQRLEKKIASGADYIMTQPVYDVKLIASIKEATAHLDVPIFLGIM
PLASGKNAEYLHNEVPGIQLSDSVRSRMEGLQGEEGRRVGVEIAKELLDAAMDHFNGIYL
MTPFMFYEMTATLTKYVKEKSKERGAHLFHS
>A0A8H7DGK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycena sanguinolenta|TrEMBL
MKITQKIRQSDKENKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTAEMVKTCQGLIGIETCMHLTCTNMPRTKVDVALREAKKSGCRNVLALRGDPPAGKEE
WEAVEGGFVHGIDLVKHIRREYGDYFDLAVAGFPQNQLLPQEERDLEMKYLKEKVDAGVD
FIFTQMFYDVEVFIDWVKAVRAAGITIPIVPGIAPIQNWNGFMRATSLAKTIIPQSFLDA
LEPHQNDDEKVREIGTKLVADMCRKILSENLGIRGLHFYTMNLEKGTKMLLEELDLVPRV
ETIKPLPWRQSLTPNRRTETIRPIFWANRTQSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGEPKTLAEIASLFARFCTKDLRALPWSDQAPASETSVISSQLA
RMNEYGFLTINSQPAVNGVKSEDKVFGWGPRNGYVYQKVFSPLFIAYLEFFVNPTLLSLL
LAHIERDSNITYYVINKRGDLRTNSHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDE
AFELGQQWAKLYDADSPSRKVISELMDTCFLVNVVHNDFHDTNAIFEPFFKAGAEYAAME
NKPESAPLQPNGH
>A0A6N8ZJY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDGGTCRMPISNTTTCAPTSGGCAAAGGSEGGRPLASDETPPPASTRTRAALRALALGAS
AEILPGQLPSPEVLARHLPRATSVYIPYPPKGRWPDTIAACEQALAAGMKPVPHLPARSV
RSAGELDDWLAGVVETGADAVMLMAGDRATPAGPYPDTPALLDSGLLAEHGLRRLGVTSY
PEGHPVIARADLDEALRRKMEYARATGSELWIVTQFVFSPSPVLTWLARMRDAGCTMPVR
IGMPGPVALGALIGYAVRSGVVASARALKRKPGIARLAGRWSPTPVALALARHLAARAEE
APVDIHLFTFGGLADAAEWLSNLRKPDELAVCPPETS
>A0A7C7SCJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTDTRLFSFEFSAPKTEEAVTKVKQVHARLAGLSPHFFSVTYGAGGSTKDGTKQTVLDLA
STGSVVAPHLSFGGDEPEIIEALLREYQAAGITRLVALRGDRPSGVGSSMKMSHANELVE
FIRQLTGEHFHIDVAAYPEIHPESDTVDTEIKFFKQKVDAGANSAITQYFYNADAYFRFR
DLCDKAGIRIPIVPGIMPITNYKGIKRFSDLCGAEIPRWIEKQLQACKAEPDTLKAFGVE
VVTDLCQRLLQGGAPGLHFYTMNQSLPTMKVWKNLGL
>A0A6G9V502|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria sp. KD4|TrEMBL
MPAPLAASEPAPVTGPPTGTSWLVRRPRRSTLVSFEVFPPRPTADPDTVWRNIDAMAQAG
PDFFSVTHGHAGHHGVSREALRHLRRTTKTPVMAHFTCGGTDRAGLERAVDQLLDDGVRD
LLALRGDPPLGTGEWRTPAGGLGRASQLVELIRDVERRRFGTGFRPGQRPLSVSVACYPS
PARGRDFEADLASLWDKQEAGADYAITQVLYEPEDYATFLERARSEGIHIPVVAGLMPLS
NPQRLQRMTEITGVRVPERLTRFLRADTPEELRHRGVAATLSLIDDLMDLGCAGFHLYTF
NRPEAALTILEHLRVRDAAREYRGRSPAA
>A0A349SH26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKQNPVVNNSPELQDSIHETKRRLAQRPFPDFISLRQQVSVSFEFFPPTSIELENKLWSC
VAQLAPLRPRFVSVTYGAGGSTRQRTHATVEKILAETLLIPAAHLTCVGAPRDEVDEVVR
RYWDIGVRHLVALRGDSTDPGRAFISHPQGYQTAAQLVAGIRKIADFEVTVAAYPEIHPD
AESQEADLDNLKRKLDAGANRAITQYFFNADDFLRFLDRVRAAGISAPIIPGILPVTNFA
RVVKFSEKCGATIPVWMRDLFAGLDDAPDIRQLIAATVAIEQCRLLLEQGINEFHFYTLN
RAELTQAICHALGLREYPEHSLCELNAPGE
>A0A7C1TP01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
METQRKHPQQFSFEFFPPKTEEGRTKLKATLEQLGALQPKYFSVTFGAGGSTQQGTFDTV
KMIMDAGYEAAPHLSCIGSTRENIRAILEKYRTAGIRRIVALRGDMPSGMREAGEFHHAN
ELVAFIRETTGDHFHIEVAAYPEFHPQAPGARADMAYFRDKMAAGANSAITQYFFNPDAY
FRFVEDVEKLGVDAPIVPGIMPITNYTQLARFSDMCGAEIPRWIRKRLEDFGDDRDAIRT
FGEDVVSELCHQLLEAGAPGLHFYTMNQAGPT
>A0A2D9WWR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSSEELILSQTDHSSSQPSLSFEFFPPRDEDGIAKLLQGAITKLATFNPDYCSVTYGAGG
STRQGTQDLVQAMLATKISAAPHLSIGGSSDAALDQLVEYYQEIGVTKILCLRGDQPSGD
ASKPAYAKDLVERLQQRFPKQFELAVAAYPEVHPDASSAEDDLAHFVAKVNAGASSAITQ
YFYNPEAYGYFLDRCAKAGVSIPITPGIMPITNINALQRFSAKAGADIPRWLAKSMSSYA
SDDKGLVDFGVEVXTKLCERLLELGAPGLHFYTLNRWGASSQLCRNLGFLER
>A0A3D5FHD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSRAANLEEPGTGFKSDSHLERVLAGGHFAVTGEIGPPKSWDAEVIRQKAKLLKGYVDGA
NITDNQTAIVRMSSIAAGIIVKQEGLEPVIQMTCRDRNRLAMQSDLLGAAAHGINNVLCL
SGDHQSFGNHPGAKNVHDIDSLQLVQMVKGLREGHFQCDEEIKGGGPGYFIGAAANPFAE
PLEWRPFRLAKKTAAGADFIQTQLVYDIPRFREYMKKVVELGVHERTAILAGVGPLKSTG
MAKYMRDRVPGMSVPQECIERMAGAVA
>A0A3C0KZ60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MLVAAEVKRKGLDVILQLTGRDRNRIAIESELLGALSIDVNKVLCLTGDQPAPDGPKAVN
EYNGTGLIQLAT
>A0A4Q5Q445|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTDSQPRLSFEFFPTKTPEGKEKLIKVRDQLNEFEPDFFSVTYGAGGSTRDNTKGIVTQF
ATDGISIAPHLSFGSDDEATILQLLGEYKAEGVDRIVALRGDLPSGMGGQQQLVYANELV
AFIRKHFGKQFHLEVAAYPEIHPQAKSYADDINFLKGKFDAGADSAITQYFFNPDSYFYF
LEQTRKAGITQPIYPGIMPIINYRNLTRFSDSCGAEIPRWLRKALENYGDDEVSLKAFGI
DLVTELCEVLLENEAPGLHFYTMNQTEPTAQIVKNLGLVPAE
>A0A523LBD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSQLEKVLRANQFAMTAETSPPDSASADEVLDRVNCLKGIADAVNVTDGASARVHMSALA
AATIMARAGIDPVLQFTTRDRNRLALQGDTLGASALGIHNFLCLTGDKMTAGDQPDAAEV
FDIDSGELMRNMRDMRDLGTYPSGREIEPRPALFLGGAEVPSDPDADWSPARILAKIDNG
AQFFQTQYCFDLGIVERYCHRLVEEGITEKAYFLIGIGPLASAKSARWMDANLFGVNIPE
AIIKRLDGAKDQKAEGRKICAELLQGFSEIEGCAGAHLMAPHQEAACAQVIQESGLLKQR
I
>A0A2D7I859|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTHINKTSETVAKRIREDLEKSYMEIIPVPGIEDRVGPLPSDMYLAVTCSPTKGVDETLE
LSXKLIAXGFKVTPHIASKCVSDEKHLEXIIKXLDELGIESIFVPGGDRPEPMGDFNNAL
DLLRALKKLGHNLNKIGMAAHPEGHPDVSNEVLMEALEEKKDLADFIVTQMCFDAKILND
WMVEIHKKGIELPVWVGLPGVIERGRLLKTSLRIGVGDSLRFLRKKSQVATELMKSSIYN
PDDLLKDITEQNDINQTNLAGYHIYCFNQIETTEKWRSDRISALI
>A0A1H2TM89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibacter oricola|TrEMBL
MKVTDHIKKANGKTLFSFEIVPPQKGQNIQDLYNNVDPLMEFKPPFIDVTTSREEYVYIK
KENGLLEQKMTRMRPGTVGICAALKYKYDVDAIPHVLCGGFTKEETEYVLVDCHYLGLDN
IMALRGDAMKHEQYFIPTKDGNNFASDLVGQIKNLNEGKYLHNIIETNNKPDFCIGVAGY
PEKHLEAPSMETDLRRLKEKVDAGADYVVTQMFFDNEKYYSFVEKARSIGITVPIIPGIK
PIAVKRHQQILPQIFRLDLPENLISAIEGCKDNKQVRQIGIEWAIEQSKDLIANGAPVVH
FYSMGKSDNIKAIAKAVF
>A0A4Q4R6J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria gaisen|TrEMBL
MERITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCIGVAAYPEGHSDQSHPQHQDPQFDL
PSLIEKTKAGADFIMTQLFYDVEAYDKFEKMLREHESGVFKTMPIIPGLMPIQSYKILLR
TTTLSHAKLPSDMLARLDAVKSDDELVKQEGVKIMDEMVEHIKARPDTCRRGFHFYTLNL
EKAVSHIVEDTHLIPSTIDDNDDVIVETTPAINLEPPPNGFVPHRRRSSAVNSGPRNRVI
ISHSSAAKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKDDISKLFRRHIEGDLEAIPWSEQSLSP
ETLTISKQLLALNAKGWWTVASQPAVNGVKSTDPVFGWGPKNGYVFQKPFVEFFIPASEF
AALKPKLDAHEQVTYFAGNAAGEFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIFQEWQRIYPPRSASSTLLGALRRDYWLVNVIWGDFVQGEGLWEFLEQ
>A0A523LAZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIAFEKLNPAEPLSDLKGHVSRGRFERLLKSGYFTVTAELAPPDSALAEDVYERARIFDG
YVDGMNATDGSGANCHMSSVAMCALLIGAGYSPIMQISCRDKNRIAIQGDVLGAAAMGVC
NVLCLSGDGVQVGDHPEAKPVFDLDSISLLNAIKTMRDESKFMSGRPITTPPKMFLGAAE
NPSAPPIDFRPYRLANKIAAGADFIQTQYIFDVPQLKEFMSRASDMGLLEKCFILPGVGP
LASARTATWIRDNVPGIYIPDHIIERLAGAENPKLEGQNICVELMQQIREIPGVSGIHVM
AYRQEQAVPDIIQRSGVLDGRKPWYPGCED
>A0A496W722|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSKKQALTTSCEFFPPRTDKGVLKLHKVREQLEVLKPAYFSVTFGAGGSTQEKTFETVVE
IQEQSDFDAAPHLSCIGSTRENILKLLQGYQAHGIKRIVALRGDQPSGWAGPLGEFRYAN
QLVEFIRAETGSHFQIEVAAYPECHPQAQSTKADLDFFKQKVQAGANSAITQYFYNADAY
FRFVDSCAERGIDIPIVPGIMPISNFEQLARFSDTCGAEIPRWLYGHLKDLEADKAALQA
FGVDVVTKLCERLLAGGAPSLHFYTLNQAGLILEIAKRLDLF
>A0A5A9ZEV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. ANT_WB68|TrEMBL
MTKPAISFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALCA
RGETAIAPHMSCIGDDKSEIAELLDLYKSLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREYSGDHFRIEVAAYPEMHPQARSFELDVENLVNKYQAGANASITQFFYNADSYLYLR
DSLEKRGIDTVAQPLVAGIMPITNSSNLVRFADSCGADIPRYVRKRLADFGDDRTAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLIEALGLTA
>A0A523L9S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGIDKPVIPGILPIHDFDKVQAFSQRCGTSVPQSYRACSRR
>A0A0C2ZCY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp. AS07-7|TrEMBL
MFDTFCSKLHSDKPFITVEITPPHGSSMDKIIASIEDIGLHKKVAGFSVTDNPLAKLKMS
AILSAIKVQQHFNLPVIATMSMRDRNKLSLQSSILGANDFDLRCILALTGDPAKFSDQPE
VKGVLERDSTLLLSIIYKLNQGLDYSNKALNPAPKPIYPFAVSNSYAKDMKNIQKKMIKK
LNYGARAIITQPVYDLANAKKLIEIFEEAKEISIRESAKEAQLILGQFPVVRAKTANFIA
DKVPGISVPKEIIDEMNLASMDGEAKEQEVGFALSKAIFDEILTNHGKIHLMTHNRFDLC
ADLIKGVN
>A0A661CMI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
RCQAKGIDIPIIPGIMPINNFTQLARFSDGCGAEIPRWLRKRLEAFNDDTESLQAFTLDF
LTDFTQKLIVAGVPGLHFYTMNRIDPTLTICQRLGLTS
>A0A1F8SQD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_19FT_COMBO_47_9|TrEMBL
MECPKGERNGPCGGSTTEYCYVDKTRPCVWYKIYDRAFKMGRQEMLMEVLPPLDWDKTGG
ETWADVYHQIKKVGAKNFFGGVLSGGEKRTTAWSSVFRPVRQPEWWNGDSEYHPPAYTEP
VSNLERRLKAGEFVVTAEVAPPMTVSTNKLLKNIEVVKPYAAAINFTDCPSASPRMSSWA
CSALTVQAGAEPVMQIAARDRTRIGLQAEILGSNALGVRNILCLSGDSMEMSSVPKGKMD
ILDMDSVHMLWILRRMRDESIYMDGRQIKFPPKYFLGAAGSPFASDPRIQAIREHKKVNA
GAQFFQTNLVYDPDGLDDWLEALDKRGILEKVYILIGITPLKSLKVANYMNEEVPGVTIP
EKLVKRMEAAGDKADEEGVQIALELI
>A0A1F8MYW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_54_8|TrEMBL
MPNSLFEEKLNSNGFLVTTEVGPPKGTDVAEMVHHIDSFKDKVDAINITDHQSSVMRFPS
LGGCLLVKERGGEPILQMTCRDRNRLALQADLLLAYSRGITNVLSLTGDSIDVGDNKEAK
PVFDLDSVQLLKMMRTIESGADMGGNPLKGAPRFCIGASVHPEADLIEPQLIKFEKKVAA
GAQFFQTQGIFDLASLRRFMQYASQFRTKILAGIIVLASARMAKYMNDNVPGITVPQATI
DELASAEKGKGLQKGIEIAARMIKTIKEENLCHGVHIMAVGNERVVPNILEAAQLDGGHH
>A0A661CWZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
RCQAKGIDIPIIPGIMPINNFTQLARFSDGCGAEIPRWLRKRLEAFNDDSESLQAFTLDF
LTDFTQNLIAAGVPGLHFYTMNRIDPTLTICQRLGLTR
>A0A7C9P9J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuriferula multivorans|TrEMBL
MTERTFSFEFFPPKTAEGMDKLRATREQLAQLKPKFFSVTFGAGGSTRDRTLETVRDIQA
SGSAAAPHLSCIGSTEESIREILTEYKSQGIRHLVALRGDLPSGSMDAGEFNYANELVAF
IRRETGDWFEIEVAAYPEVHPQARSYTADLVNFKRKVDVGANSAITQYFFNADAYFRFVD
DVRAQGVSIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDMASLRAFGLDV
ITDMCDRLLVGGAPGLHFYTMNQAGPTTTIWQRLGL
>N9NUD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 2168|TrEMBL
MSLFSQCLEQKRFCILVEYLCSKRDTLAVTKSLAGFPAMMTLADRVHSDEDPAPLELAQR
YSSEIEKLLHFSGKGRDIKEFEHFLDQAEQQRYHNLLLLTGDKLKNHNFGREIPAQRSRY
LESVSAVMAAKQRNVFNIGVAFNPFKYTEAEQDAQYLKLHKKIKAGADFLITQLGFDLDC
LQHSQSFISQNYKQFPLIACVMPLTLKRAQFMVKNQIAGLVIAPHIVDVLEREYAADPVQ
AEANVYARCALQILICKHLGYVGVHLSACHKPQEQQKLERFLNQFENWSLAACEKAWKDL
WKMDSGLELKPELSTFSKPVSQIQILKYKKMHLMHHIFFASHAALGVGRFIFKANFWNKP
RPQHLLLKMEHWSKQQLVGCESCGHCRLDDTLYICPETCPKGLANGPCGGTTLDRCEFGD
RECIHSVKARLAKSIDQTEVLRSKLIPAISIETRYTSSWKNWFRNSDLN
>A0A444L5L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanosuratincola subterraneus|TrEMBL
MREAFSRLISEIRSGKFVYTGEIAPGKTTRVETLIESAKALGRHVVACNVTDNPRARANM
SSLAASIAVQERAGVEAICQMTARDRNRIALTSDLLGASALGVRNVLVMSGDHPSLGDNP
SAMPVYDLDSAQMVELVRRMVDDGTDLAGNRIDGKVRIHVGVTGNPNADPLEVEIAKLER
KAQLGAEFIQTQAVFDIEVAERFLEAVDGFGIPVLIGILPCRSSRIAEQIAKNVPGIRVP
EEYLGMLRGAEDLNDQASVEERVDLMNEEYFSGMVSELRRTARLAGVHIMGVAYGRIVGR
IADGVERKMSCRVR
>A0A151BEY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon B25|TrEMBL
MVSLACGIGVQVLNEVFPQVQTFPGNDTVFNGMQPKEGGVFEERCLSCGSCMLGETGGIC
PVTMCAKGLLNGPCGGFFEGKCEVGGWVNDCGWVKIFDRLKELGKLDIFTKIRLPKDYRD
MQNPRKLSLAEVATKKAIPEVIDEVKEPGKRPAYSELMKKIRRGEFVVTGEVEPVKTTDL
TEVLEAAESLKDYVTAINVTDNPTAFAYMNALIPSYTIQEKTGVEAVYQMVARDRNRLAL
VSDLLAAGALGIKNILALSGDTTTMGDNPGARKVWDLDVTQFIYMISRIVDEGVDLAENK
IQNPPKFNIGSSANPCATPLEPEIYKLVRKQNAGAEFLQTNSLYDIEIIKHFLSECRSAG
LKIPILIGITPFKSVKMMDWLVKYVPGVVVPDEIQEKLRKAREKSKEAFVDKNIEIFSEL
CREIRKTTPAAGIHMMAIGFEWVVPRILKEAGL
>A0A5P8VUN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sphaeroides CCNUC1|TrEMBL
MHHTHSPTAFQRAVEAGEFLVTAEVAPPKGGDPAHMIQMAATLKGRVHAVNVTDGSRAVL
RMSSLMASVILSQNGIEPICQVACRDRNRIGLQADLMGAHALGIRNILALTGDPVKAGDH
PDAKAVFDLEAVRLLQLIRKMNQGVDCNEKPLTDGALDLFVGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFERLEKFMDNIAAGYKKPILAGIFLLKSAKNAQFINRCVPGVN
IPQHIIDRLAKAKDPFEEGIKIAAEQVQIARQLCQGVHMMAVKREDAIAPILDLAGIAPV
NQLVSK
>A0A143XA86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriaceae bacterium CHKCI002|TrEMBL
MTTIRSIYRTARACGRRPVSFEIFPPKGDLTLDVAHDVAGQLAELAPDFISVTYSAGGSG
NKRATADVAQMIQRDFDVPAVAHLTCVGATEETIARAVDDLRAHGIDNVLALRGDAVGAD
EPGEYRYARDLISRLAEEGFCVGAAAYPEGHIACDDARANIEHLKQKQDAGASFFVTQLF
FDNEFFYRFWEAARNAGVTAPIACGIMPFLGKTQIQRMVFMCGASLPSPVVKLLARFEDR
PDDLRRAGIEYACAQLVDLDAHGVDGLHVYTMNQPDIARASMAALRAAWQA
>A0A4S2IUD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S816|TrEMBL
MNPAVTAPAAVGTDLLDDFSLEMTGKDVPALEEARDSIPQGTRINVTFLAGEDHATRLAA
ARAVRRLGFVPVPHISARRLPSAAALEEFLAGLAEDGTADNVFVVGGDPARPEGPYEDAL
AVLRTGLLERYGVRHIGISGYPEGHPAISGPALWSALTDKAAAIGAGPFTGDVITQFGFD
ADPVLDWLAAVRARGVGLPVRIGVPGPAGIRRLVGYATRFGVTTSASVARKYGFSLTNLL
GTAGPDRFLHALGERYDPARHGVVKVHFYTFGGLRTTAEWVGGFRERTR
>A0A0C9PY85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Brocadia sinica JPN1|TrEMBL
MDLKSGSNLEKVLQSGQFAVTAELGPPRGADRSVIEKKAGLLKGYGDAFNITDCQTAVVR
MSSIAAGRIVLDAGLEPIIQMTCRDRNRIAIQSDLLGAAALGAKNLLCLTGDHQKFGDHP
MAKGVFDMDSIQLIQMVKAIRDEKKFQGGQELKASEPRFFIGAAENPFADPFKFRAIRLA
KKIAAGADFIQTQIIYNINKFKDWMKMVTDMGLHEKAFILAGVAPLKSAGMARHMKHNVP
GMDVPDEVINRMTAVSAAKKGKEEGIKICLEVIEQIREIKGIAGIHIMAVEWEEAVPEIV
KETRLYPRPLL
>A0A354WFP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktothrix sp. UBA10369|TrEMBL
MNRFRTACQTLDEFIITAEVAPPKGADPSHMIEMVRLLKNRVHAVNITDGSRAVLAMSSL
ASSIILLHHGVEPIYQVACRDRNRIGLQADLLGAQALGIRNVLALTGDPVKAGDHPDAKA
VFDLESVRLLQAINKLNQGKDWNNKALPDGATDLFPGAAVDPQSSSWSGLKSRFERKIEA
GAQFFQSQLITDFERLDKFMTEIAGESKKPILAGIFLLKSAKNARFINKYVPGVCIPDAI
INRLEKAKNPLEEGILIASEQVKTAHQLCHGVHIMAVKREDLIPEILDLAEIKPFL
>A0A2N9XR98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snodgrassella alvi|TrEMBL
MSFTSLSFEFFPPRTEEGRRKLAITRKQLSQYQPEYFSCTYGAGGTTRAGTLQTITDILN
DGVAAAPHLACIGASRQEMISLLQTYKDMGIRHIVALRGDIPSGVGFGHQGLRYANELVE
LIRQEFGDWFHIEIAAYPEFHPQSRSAEDDINHFVRKCQAGADSAITQYFFNADSYFWFV
DEVQSRGVNIPIIPGIMPIASFSKLARFSETCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCDNLLQQGAPSLHFYTLNQAGLVSTICQRLGY
>A0A095AV61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. LC81|TrEMBL
MTSNLNSLAEARRAAASPLFANLEGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASRAEIDEVAQAYWDAGVRHIVA
LRGDVPGGAPYRAHPDGYANAIELVAGLKAIAPFDISVAAYPETHPDADCPQSDLDNLKR
KLDAGATRAITQFFFSPDSFLRFRDAAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMISLFEGLDDLPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPAAAPATEKAA
>A0A3E0CBY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus versutus|TrEMBL
MTTPAISFEFFPPRNLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETLQIVQDYAAAGVHEIVALRGDAPQGQDRFTPHPEGFANSV
ELIEAIAARGDMTIRCGAYPEPHPESSDTAADVAWLKRKVDAGATSAMTQFFFDAETYFR
FRDACRAAGIEAPIIPGILPIQSWAGTRRFAERCGTSVPQWAEDAFAAAGKEGEAQLALD
VCVKLCERMVEGGVDKLHFYTLNKPELVLKVCAALGIEPKGEFSRVA
>L1NUQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria sp. oral taxon 020 str. F0370|TrEMBL
MSAAEKTLSFEFFPTRTPEGREKQIVTRKQLRQFAPEFFSCTSGAGGTTREGTLQTIADI
LAEGTPAAPHLPCIGMTVEEVKSLLDTYQDMGVRHIVALRGDIPSGMGAGGSGLRYANEL
VELIKNEYGSHFHIEIAAYPEYHPQARSADEDIENFVRKAKAGADSAITQYFYNADAYFR
FVDEVQGRGVTIPIIPGIMPIASFSKLVRFSDTCGAEIPRWLRLKLQSYADDTAAIKALA
LDVVTEMCSRLLEQGAPGLHFYTMNQAGLVSTICQRLGY
>A0A137QYE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucoagaricus sp. SymC.cos|TrEMBL
MKFTVKFAAQPPQRPFFTFEFFPPRTDQGFDNLVARISRLAALKPLGVSVTWGAGGATRE
RSLELASLTQRDYGLETLLHLTCTNAEVGSVDVALKDAKERGIQNILALRGDPPRGQEEW
VPSDPRFTHAIDLVRYIRESYGDYFCIGVAAYPDGHPDKLVDEEQELIDLKAKVDAGADF
IITQLFYDVDGFLAWLRKVRQKGINAPIVPGVMPIQTYGSFQRLTKLTGAKVPERVQEAL
KTISHDDQLVKDYGVTLAVEMIRKFVSEGAVQGVHFCTLNLEKSVQRVLENLQWTDAKAF
EKEALDGPTNEHDTDLLVTATTATHDATHSLASITVSDGEAGRGELNNAASWDDFPNGRF
GDFKSPAFGAQDPWGNSGINAINEVLKQWRNPKALPELTQIFLDHLRSRISTTPFSPGPL
SPESLTILPELEELTERGWWTVGSQPAIDGVSSSDETFGWGPNAGYVFQKGFVEFFCEEA
DVQIIERKIEQRGRGWVHYFAGNYKGEFKTNVPDDGRNAVTWGVFPGQEIIQTTIIEHES
FLSWKEEAFSIWSDWSTCYRPGSEERKLLEDVRDQRWLINIIHHDYRDPRALWDVLLNDR
TVNGI
>A0A418M794|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicyclobacillaceae bacterium I2511|TrEMBL
MAERPDFRVLARQRVLVGDGAMATLLHRYGAPIRTCYPALSVSHPEWVRQIHKEYLRAGA
DLIQTNSFGAHRTGLEKYDLADALQDINLAAVRVAKEAVAQVQLDRPVYVFGTVGSVVSF
QNAAGLMGPDHVVAVQNEFAEQVTVLLKGGVDGLLLETIADLSEMRIALQTVRSLTTLPV
VAHLAPDTVGVTRDGVPIQRALQEMYQLGADVVGLNCHLGPRGILRTFEGFHGDKALIYS
AEPNAGLLHQVEGDYSYTGSTDYYTGVAKQLLDAGVTLLGGCCGTTPEHIRRLAELAQQA
NQSGSPQAVRTSLGTVVGPVGPAATATVSGSFTAGLPARDAVAADVRTTLPARVSTSPKQ
GSPTFAASVVDWVHQRDTVIVELDPPKTLDVGKYLQGAQALQEAGADAITLADNSLGTVR
VANMALASLLKGMGIEPLVHMTCRDRNLIGQQSHLMGLHVLGIHQLLLVTGDPTRFGDLP
GATPVYDVSSMELTRMVKQLNQGVAFSGQALSHPAHFVVGTSFNPHVVNFSRAIERLRKK
VEAGADFIMTQPIYEVSMFEAIASATEDLHIPVFVGIMPLVSARNASFLHNEVPGIRIPE
PLLARMAAAPPAGAAAVGLQIAEQLIDRARQYFQGIYLITPFLRYGLTVHLTRYIKSNQI
TREMDGGQFLDRPDRL
>A0A386H9H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia rochesterensis|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMTRIFD
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A0T9UHE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia enterocolitica|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLRDIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A5B1B8R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimarina sp. RZ0|TrEMBL
MKVTDHIKNAKGKTLFSFELIPPQKGRSIQELYDNIDPLMEFKPPFIDVTTSREEFIYID
RDGLLDKKLTRMRPGTLGICASITHKYSVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFIPTQGGHCYASELVKQISNMNKGQFLHEVIETDNKSNFCVGVAAYP
EKHMEAPSMDSDIRRLKAKVDSGADYVVTQMFFDNKRYFAFVEKARAAGIEVPIIPGIKP
VAVKRHLQLLPQVFKLDMPDDLVQAVENCKNNKEVRQVGIEFSIQQSKELMDYGVPVLHY
YSMGKSDNIKKIASAIF
>A0A1M4STQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loktanella atrilutea|TrEMBL
MTRPKISFEFFPPKNLEGSFRLRDCVNALAPLEPEFVSVTYGAGGTTRKLTHEAVTAIDR
TTGLRVAAHLTCVDATRAETLAIAEEYAAAGITDIVALRGDAPKGSEKFTAHADGFASSV
ELIEALAATGKFTLRVGAYPEKHPEAASQDADVAWLKRKIDAGASAAITQFFFEAETFFR
FRDKCVKAGIDAPIIPGILPVENWKGASRFAKATGTSIPPVVAQAFAHATEEGQADMLAT
ALATELCDELLADGVEHLHFYTLNKPQLTHDVCRALGIAPGARLQNVA
>A0A4Q0ZU70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp. CECT 8985|TrEMBL
MFQSLIQKLQEDKYLTLETTPQHEPIMHNIIERIKKFDLQNRVDGFSATDNPLAKLKYNA
LFASLRLQQEFNKPVIATMSMRDRNKIALQADLLGANEFDVRAILALTGDPAKMSDQPHA
KGVFESNSSMLLKIIKSFNYGMDIAGHPFKIEPKQIYPFAVTNAYARSFSSLEKKMHTKI
QNGAMGIITQPVFELDNAKKLLETFNEAKEGVVGNKKKAQLIFGIFPITKLRTALFLSAQ
VPGIHVPQNWIDKLEMANQISPEEEYKVGMQLSKDLFSNIKKLHPKIHLMTANKFDLADE
ILS
>A0A1B7NTF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emergomyces africanus|TrEMBL
MHIKDKLAHAETTGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFVDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAALQKKWEATEGGFRYAKDLVKYIRNK
YGNHFDIGVAGYPEGCEDQDDPELLMQHLKEKVDAGGTFIITQMFYDVDNFLDWVKKCRD
NGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEALEPVKNDDAAVRTLGKSLVAQM
CEKILAAGIHHLHFYTMNLQQATKMVLDELGLIPSHQTPLQKPLPWRQSLGLGRRGEDVR
PIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDTYGIGLKGTNEQNVKLWGEPKS
LKDLSDIFIRFLNGNLDRLPWSEGPVTEETEVIKSDLLNLNERGFLTINSQPAIDGVSSS
HPVYGWGPKNGYVYQKAYLELLISPTMIDDVISRIEQNSDLTYYCVNKNGELKTNTTDSP
NAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWAKCHAATSPSRHLIQQVMDSWY
LVNIVNNDFHKTHDIFNLFKDLEVKNLDTEVEAIIPAAEPVDNTQQNGQSLEKHVNGTAT
EATDSEQKPNSN
>A0A374LEX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. OF05-2BH|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPE
AMKQAGIAYATDQIIDLLANGVNNIHIYSMNKPEIAIAIMNNLSEIIKC
>A0A5R9BA25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nesterenkonia salmonea|TrEMBL
MNPKLPADSLVSPAHRHALRQLLAHPRFEVLPLDGIVDDAVAHLPVGATVTITASPTRGP
GPTLETTEDLASQGFRAVPHLAATQHRVGSLPHTMGRLQAAGIQEVFVVGGDQADGLASR
GKGTASQDAAFASGWELLAAVHRLAPELKLGVPGYPEGHPKISQRTLDESLTQKAERASC
VVGQLCFDPQTVSDWATGLRARGVNLPVYAGVPGAVGSARLLRIAGRIGVGDSLRFLASG
KAGLAMRLATSGHFDPTPLVAGLVSKGDVVSGLHLYTFNALKETEIWRQRLLTWLEEGDH
>A0A376B3U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomycodes ludwigii|TrEMBL
MKITEKLQRQRTKEPSKPTFSFEFFVPKTLQGVQNLYDRMDRMYLTNPQFIDITWNAGGK
VSMNNANTNDLIHTCQSVLGLETCMHLTCTNMPVEKIDEALQKAYDSGCQNILALRGDPP
VVDEKAQQSNALKYDGFNYAKDLVKHIRDKYGDYFCIGVAAYPEGHPEENNVDILIDYLE
EKVNAGADFIITQMFYDTDSFIEWCGKVRAKGIDIPIIPGIMPIMSYDSFLRRAKWCQIN
IPKFFLDKLDPVKEDDQAVRLLGTDLVVEMCQKLLDSGYVTHLHMYTMNLEKGSLIILEK
LKIIPPLHLTTLTTVNQFAISTEHDDNLPWRKSLNPQRKNEMVRPIFWQRRPYSYVARTS
EWEADEFPNGRFGDPNSPAFGGLDLLGSSLIRQSGKNCLQLWGHPTTLKDFGDLIVKYIS
GDLKCLPWSDTPITSEVDSILHYLKDLNKHLIFTINSQPKVNGLPSNDKVFGWGPKNGFI
YQKGYLEFLLPKAELGRFLELVNSNDSLTYYAIDNDSNLYSKDGSEKENADSDNASEIPG
SKANSVTWGIFPGREVLQPTIVEKESFLAWKDEFYEILRQWKINFDNHEGNEKSADLINS
IINDYILCNVVDNNFISPEQQIYSLLTQLY
>A0A0Q9R9J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Soil782|TrEMBL
MMFPTRIEIIPSEGIVERVAAAVAPSTPITVTCLPHHGVERTVRTAAQLAGLGYTAIPHL
AARSVQSRAELTEILRNCSDAGIGEVFVIGGDRRHPAGPYDSALPLLEDIGQYSSGLIRA
GIAGYPEGHPFLDPGAGVDALLAKQHLASHVVTQMCFSAPRILDYVALLRRVGVQLPVWA
GVAGAVPRTRLVSLAAQIGVGSSLKFLTRKGPLARKLLVGDHYTPESLVAELKSQPGKLA
GIHLYSFNSLDPNPHGTDHGSTATKLLRGAPHGNN
>A0A4R6ZWA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas ventosae|TrEMBL
MSMQEHPLGISFEFFPPSTDAGREKLVGVRDALASRAPRFFSVTYGAGGSTQDRTLNTVR
MVRESGFTTAPHLSCIGSDKGALRELLARYREEGIDSLVALRGDMPSGMGGGGIGQLRYA
NELVEFIREETGDHFEIAVAAYPESHPQAANLEQDLANFARKMKAGADIAITQYFFSAES
YFHFVDRARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIG
AFGEEVVSRLCQRLLDGGAPGLHFYTLNQATPCLRILDNITG
>A0A7X7P824|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp|TrEMBL
MKFKMPSSIALELVPRDLNLFLDESRLNLDRYPFIQKINVPEIRSVEIKSFEASKVLLEH
SLPAVPHFRLIDRTLDDLLKKLSSLQEMGLKEVLLIGGDPPKNGEFVPSGLTTLEAISQV
RKAFPSLKIYAGLDPYRSSFRRELDYAKQKLDAGCNGFYTQPFFSLKVLDLWLEQLSSTE
LWFGISPVHSDKSRKYWEKVNQVVFPADFSYGVKENIDLAKVLLNRIAEVNCNAYFMPIT
ISASDYLKDLFAGDDE
>A0A7X7IAC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp|TrEMBL
MKIKEMFETKSTVMSLEIFPPKLTSPVETIYATLDALSDIKPDFISVTYGAGGKAKDRTV
EIASKIKNEYRIESMAHLTCISATKEDIKKAFADMRANNIENVLTLRGDIPEDPNFEFPN
PLQYEYAFDLVREAKAEKSFCIGAACYPEKHIECESKVQDIKYLKQKVDQGADFLITQLF
FDNEVFYRFMEEIDLAGVNVPVSAGIMPVLNKNQILRITTLSGCTIPPKFQRILDRYENN
PEALKEAGEAYAIEQIIDLMAWGVRGIHLYTMNKPETAGRIMSNIEHIRRLQG
>A0A7H8HVM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. Hca4|TrEMBL
MTSVIERLRGDGPKFSIEFFPPRDTADEAVLWKAIRELEPYDPAYMSITYGAGGSSRDGT
VRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYASVGVRNILALRGDPPGDVYGEWI
PHPEGLTYAEELVQLVRELGDFCVGVSAYTYGHPRSADLESDTKYLVRKLRAGADFAIAQ
LFHDPEDFLRLRDRVAATGCDVPVLPGVMPLTTMRTLQTTIKLSGAPAPRKVLDRLEPLA
DDPKAFRAAGIDVTTELCEKLIAEGVPNLHFYTFNRSKATREVIARLGLVPARA
>L7Y7D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blattabacterium sp. (Blatta orientalis) str. Tarazona|TrEMBL
MKVTDHIAKAKKSLFSFEILPPLRGHDIKDIFYTLDPLMEFNPPFIDVTYHREEFIYVEK
ENGLLQRRTISRRPGTVGICAAIMNKYGIDAVPHLICGGFNRQMTENALIDLNFLGIDNV
LVLRGDPLKSEKSFFSKKDGHQYAVELVEQVQNLNNGKYLDNTFEQKDSPLFDFCIGIAG
YPEKHLEAPNMESDLFFLKKKVEAGANYIVTQMFFDNHKYFSFVKKCRSEGITVPIIPGI
KPISSKKQLNSLPSRFYLNIPHELVKEIEKVKDKKMISHIGIEWAIQQSKELKDSGVEVI
HYYTMDKPENIYKIVQAVY
>A0A6N8XWG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Holophagales bacterium|TrEMBL
MTAPTVSRVSAVGAPSRRRRCSRTTSTSRRSRTSRGSGRSRCGGGTVWRRRSARSGRRRS
CSGSSRPWSATRRSAVPSTNSAGAARGPSWGRWRDGWRRPAWSSRRSGWRRTRRRIRFVV
KLIDKLRSAIAEERPFYSFEYFPPKTEAGIENLYARIERMGRLEPAFVDVTWGAGGSTAE
LTFELANTIENVLGLETMMHLTCTNMPRRRIAAVLDDCRARGIGNILALRGDPPRGRGAW
SPIADGFSHASDLVRFIREEHGDHFGVCVGGYPEGHPEASSRERDLDHLAEKVATGADFV
ITQMFYEPELYFRFLKECRERGVDCPIVPGLAPINGYLSFQRITGFGASAPPEIVSEIEA
RRFHDASVREYGQDLLTGICSRLLEGGAPGLHFYTLNLERSVQVILDRLDIVPERIERVL
PWRSATAVQRPREDVRPIFWANRPKSYLARTQDWDEFPNGRWGDAGSPAFGDLGDHHLAF
RPIRADLARERWGRELHSIDQVREVFAGFCRGDVDGIPWYDWPLDLESEPLRNALVRLNL
AGLLTINSQPRVNGAPSDDPAVGWGGAGGRVYQKAYLEFFVAPEQVPTLLAALDAGPSLT
YHAIDRSGTAHSNCDTVNAVTWGVFPGEEIRQPTIVDPRSFEVWKDEAFDLWLSSWAAVY
DEGSESRRLLQRIHDTYFLVNVVDNDYVDGDLLAYLIEAAQADEPPSMTIVAPVT
>A0A6I6L1G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rimosus R6-500|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVQHPEGVLYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATQLCARLMAEGSPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A1H2EY99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis keratiniphila|TrEMBL
MDLVRRIDRAAGEFLLFALTPPRLATAQERVQQIADATMARLRPLNLDGLILYDIDDEAA
RNPAQRPFPFVPTHDPANYLADNFTNWRTPVIVYRAVGKYAPSELRTWLAAQDPARVMTV
LVGASSSKIDTMTSLADAQALRRDVNPGLSLGGVAIPERHSRRDDEHLRLLAKQDAGCRF
FVTQVVYDVNAAKNLVSDYHYECVARGRAPVPIVFTFSVCGSLKTLDFLRWLGVDVPRWI
ENDLKHAADTLEASYQLALAAATELMTYCRGLGVPFGINVESVSIRREEIEASVRLAERL
RAEIKG
>A0A4D6XE49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MNAFIEYHQDIINQKIENLRNNIKCSFEFFPPKNSNSEKKLWSSVKILSKLKPNFFSVTY
GANSGERENTFNIVKAIQKQTSIITAAHLTCVNSTPSQLKKIAKNYWENNIRSIIALRGD
TLEKNYKYNMYAIDLIILLKKIADFDISVAAYPELHPESKNIQVDIINLKKKIDAGANRA
ITQFFFNVESYLNFRENCIKNRINVEIIPGILPIYNFQQIKRFSKMTNVNIPNWMFEMFD
GLDQDLITQKIIGSSIIIDIVKRLSSEGVKNFHFYTLNQSDIAYSVCQIFGL
>A0A1W9R2W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium 4484_70.1|TrEMBL
MFRISVELVPRQKETFIKDLKRVKENFPAVDTINIPDILRYEINSLEGCKLALPFFTHLI
PHLRAIAVDKRKPLPFKDFLIGNGIKEVLVVRGEQKSSSYEKANVCSTLELIKKFKQEMH
EIKVYAALDPYRTSFEEECEYVYQKIDMGVEGFFTQPFFDLNLVECYLKKLNSVKIFWGI
SPVVSLRSKHYWETKNNVKFPPDFELTLEGNKKFAASLIKLVKERENSHVYFMPIKMDVV
EYLAGII
>K5WIH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phanerochaete carnosa (strain HHB-10118-sp)|TrEMBL
MKISKKIQQAEKEGRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
DLTSELVKTCQGLIGTETCMHLTCTNMPTEKIDVALREAKSHGCRNILALRGDPPMGKDE
WEAVEGGFVHGIDLVQHIRKEYGDYFDIAVAGFPQHVTLPPEERDQEIQWLKEKVDAGAD
FIFTQMFYDVEIFIEWVKQVRAAGITIPIVPGIAPIQTWNGFIKSTTLSGTTIPQLVRDQ
LEPFKNNDEKVREIGIKLVADMCRRILAEPLGVRGLHFYTMNLEKGTRMLLEELKLVPRV
EVVKPLPWRQSLTPNRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQSREEALKLWDHPATIEDISNLFAKFCLGKLPALPWSDSSPSPETSVISGQLA
KLNELGFMTINSQPAVDGVRSDDKVHGWGPSNGYVYQKAYLEFFVSPELLECLIPHIERD
HMITYYVINRRGDLRTNSHSDGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGRQ
WAKYYEPDSPPRQLITKIMDTYFLVNVVHNDFKQPSAIFEPFIKAGADFIAKHGKSPVLN
GHTNGYATGHVNGHANGHANGNAH
>A0A176WZE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MLRSENTRHNGNIRLSFEFFPPKNAEMETQLWETVDELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLPTAAHLTCVDASRDEVHQVVEEFRNAGVRHFVALRGDPSTGIGTAYQ
PHPQGYENAAALVRGLKDLGDFEISVSAYPEKHPESESDAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYLERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPAFLDERFEGYD
EDIDGRARVAAEVAAEQIADLQRRGVSEFHLYTMNRAPLVNAVLENLGLERLRRSAA
>A0A4Q9ZZC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium laguerreae|TrEMBL
MALKNEARGRNDIRVSFEFFPPKSEEMEGQLWHAVGQLQDWDPDFVSVTYGAGGTTKAPT
LSTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQ
PHPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKANNGADRALTQ
FFFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFD
DKPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGFSRRAAKSAGAA
A
>A0A1G1EFP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium RIFCSPLOWO2_12_FULL_47_7|TrEMBL
MKISEILQKQKPCCSFEFFPPKDNDGFDQLFETIENLKKWSPAFVSVTFGAGGSTRSKTV
EIVGRIKNEIGLESMAHLTCVGSSADEVKSILDSLIVKKVSNILALRGDPPQDQKQFIKP
ENGFGFANELVTFIKKHYDFCLGVAGYPEGHIECPDKAIDLENLKRKVDAGADFIITQLF
FDNNRYFDFVDRALAIGIKVPIIPGIMPIANVSQTKRFTKMCGASIPSALMERLEKNHEN
LPLVKEIGIEHATMQCEDLLSGGAPGIHFYTLNRSTATLRILESLKTTGRIV
>A0A546Y0R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MRSETARRDGDIRLSFEFFPPKNPEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPTL
DAVRRMIGDSHLPTAAHLTCVDASRDDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYKP
HPEGYENAAALVRGLREIGDFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQF
FFDNDVFERYMERVAAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFEGYDE
DLEGRARVAAEVAAEQIADLQRRGFNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A7C1MB91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantimonas coralicida|TrEMBL
MIQDLPLPRHHIPASIEVAPKQALESRELPDLFPAGTKVYLTDVGVDSVKDFIRAVKRIS
DLGYAPVPHIPARRIRSRDELETRIRAYAEEAGVTDMLVIGGGLDRPAGPFTSTMEILES
GLFDRYGIRDVGVAGHPEGSPDFSAATAEEALRLKRDFGERTGAHMRIVTQFGFDANEFI
NWSLAIREAGIGLPIHLGVAGPAKITTLIKYAALCGVGNSVAFLKKRALALTALATTHSP
EAVVGPIERHWQATLDSPVRQIHVFPFGGLVKSAEWLTERASWPNQASSFSRDIKRQHG
>A0A6N3FTR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium butyricum|TrEMBL
MIKEFLNNNILICDGAMGTYYSEKTGNDISYCEFGNLNDKNTIRRIHEEYIEAGAKLIRT
NTFSANSKELGVSRKTLKDIIESGIEIAKEAVYNKEVFIGASIGPIRENGADENFVEVLE
EYKFIVDCFLDNNINVFIFETLSNLDYLEEVSTYIKNKKPESFILTQFAVKPDGFTRDGY
SVSKIVGEVKKINTIDSYGFNCGSGPTHALELIKKIDIGDDIVSSLPNAGFPEIIHERTV
YPNNPVYFARKVKEIKKLGVSIIGGCCGTNPSYISKLRDTIDNKPEAGDKIKRYEHETYN
EKNIIKNTFKEKVKNGDFVIAVELSAPVDTDINKIMTGAKVCKDNNIDIVTVPDSPMSKV
RADSVVMSSKIKREIGIEAMPHMCCRDKNTNAIRSSLIGGHIEEIRNILAITGDPISDAS
RIETKSVFNLNSFKLIELINDMNNEVFTSDDIFIGGALNLNVLNKEVEYGRMMKKVERGA
KFFLTQPIYDDSAVEFLKSIKERIDVKILGGILPVVSYRNAMFLNNELPGVTIPQEILNR
FSEDMSREEGQNIGIDIAVSMGKKLKGICDGLYFITPFGRVNMIVDIVNRIKEV
>A3MTL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)|TrEMBL
MEVVAEITSSLNRDLILKKLAKLKTLVDKVDIPEAPGGKATAHSLAVGVLAMQQGLEPIV
HIRLLDVNKTGLKSLLGAARLLGLEYVVLLQGDPPAEGSPVRDVTTEEAIAEAKKMGLKA
GALLSLRREYAKRLEAGADFYLALHFSHKDQLRGLPRNVYPYIIVETPKNAPLIQRLRQT
AVPPQRAVELAEEIDGLVDAVIISAPGDFEALVEVLKQIKASHR
>A0A829DPH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 2875150|TrEMBL
MSFFHASQRDALNQSLAEVLGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A564G1X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium dankookense|TrEMBL
MPTASQHRASRDGYRPIRVSIEFFPPKTEEMERILWNSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETGLKPAAHLTCVAATKEEIDDVVQSYWDAGVRHIVALRGDPAEGVG
HAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFDNEIYLRYLDKVRAAGIEIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLEDDVETRRLVAAAVAAEQVLDLVDQGVEDFHFYSMNRSDLVYAICHLLGLRAQAPKA
AAAKAA
>K6DRA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schinkia azotoformans LMG 9581|TrEMBL
MGFLQDLQNRILIADGAMGTLLYSYGVDFCFEELNLLQPDRITQIHETYIKAGADVIQTN
TYGANYIKLGRYGLEDQVKDINTAAVRLAKKAAKENTYVLGTFGGIRGIKKSAATIDEIK
RSFREQLYSILMEGVDGLLLETFYDFDEIKTVLEIARKETDLPIISQVSIHEVAVLQDGT
PLRIALKELEDLGADVVGLNCRLGPHHMTQALEEVPLPKKAFLSAYPNASLPDYVDGRLI
YESDAEYFGECAVNLRNQGVRLIGGCCGTTPKHIKAVSKRLKGLAPVTHKDVKIKENKNI
ITVTAKPTQPHLHEIVTKERSVIVELDTPKTLNTTAFIEGAKALKEVGIDALTMADNSLA
SPRISNMAMAAIVKNEVKIRPLVHITCRDRNLIGLQSHLMGLDALGIDQVLAVTGDPTKV
GDFPGATSVYDLSSFELISLIKQFNEGITFSGKPLQKKTSFSVAAAFNPNVRHLDKAVKR
LEKKIEHGADYFISQPIFNEQQFLHVYEETKHITKPIYIGIMPIVSSQNAEFLHNEVPGI
KLTDVIRRRMADCGTDREKAAIEGIAIAKSLIDMAFDLFKGIYLITPFMRYEISVELVQY
LKTKNSKNLLTRN
>T0LH90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium RBG-1|TrEMBL
MAITFLERLKKGIILCDGAMGTELYARGVPYSHCFDELNLSNPKIVSTVHQDYIRAGAEL
IETNSFGANRFKLAGFGLEDKIRDINFKSARIAREAREIMGKPVFVAGSIGPLGKPLEPI
GKITRKEAYAAFKEQTESLLEGGVDIFIIETMVNLDEMKEAIAAVKNICQLSIIAQMTFT
EEGKTVMGNSPQEIVAELEKMKVDVIGANCSVGPIGIYDVMQLMAQNSKVKLSAQPNAGL
PRLVDGRFIYLSSPEYFAEYAVKFAQLGVSIIGGCCGTTPAHISAMAKALESTTKNKASV
TVIEPPIVKERETDKIVIAPTEISEFAQKLKQKKFVVSIELDPPKGTNPQKLLEGAAAIK
KSGVDACNIGDSPMARVRMSCLALAYLIKEKVGLETVLHFTSRDRNLMGIQSDLVGAHAL
GVRNILCITGDPPSLGDYAHATAVYDVDSIGLVKIISRLNQGTDVAGNSIGNPTSFHIGV
GVNPGEENLSREIDRFNQKLESGAEYVFTQILYDIKVLENFLKKVGKVPIPLVLGILPLH
SYKHAEFLHNEVPGITIPENLRERMKKAGEKGTLEGIKMAKELFHEAKGMVQGVYLMPSY
GRYQEVLEVVEEVL
>A0A7J9XVQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MAGGAFTVTAELGPPRGAQTTGVRAKVAALRDCVDAVNITDNQSSYVRLASWAGSMVALD
EGVEPVMQVACRDRNRIALQSDLMSAAAFGVVNVLALTGDDPKQGNHPDATPVFDLDSTG
LLQAARNMRDEGRLLSGEVLDPAPQLFLGAVENAVPSSAGPGAQRLAKKVDAGAQFVQTQ
FVFDVAEFAEWMHEVRDLGLDERCHILAGVGPIRSLRGLERMRGIPGIRIPDQVAHRLGG
VPPDRVADEGHRICAEVIAQLREVDGVAGAHVMAIGQEEAIPGILQQAGVVR
>A0A420XU81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Motilibacter peucedani|TrEMBL
MDPSQQRERLFFSITPPRGSASPEEAQRIADVTIERLRPLDLDALVVYDIDDESDRNPDE
RPFPYLPTQDPGDFCSRHLADWDRPLVVYRCVGKYDPTDLRSWLVAQDPRQVSTVFVGSS
SRTKPVHSTLTEALALWRSTSPALPLGAVAIPERHTSSGQEHERMLRKQEDGASFFVTQV
VYDADAAKSMASDYFYACLDRDLEPAPVVFTLSVCGSLKTLAFLQWLGVDVPRWMCNDME
RSDDPLSASFDHCSATAADLAAFCRRLGVPFGFNVESVSIRRAEIAASVQLAEQLRTEPG
>A0A1Q8RL27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum chlorophyti|TrEMBL
MDKITDKIAALPADANYFSLEFFPPKTTMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
SQKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKDE
YRDTEDSDLDDAEEFVWAVDLVRYIRKNYGEYFCIGVAAYPEGHADESHPLGQSFEHDLP
YLIEKVQAGADFIMTQLFFDIKAYENFEKILREHPSGAFKNTVILPGLMPIQSYQMIKRT
TKLSHAKIPDNLMARLDAVKGDDERVKQVGVDILSELVEQIKEVRSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDPSIEDEVAVIDDMPVAGIPTVQLNGLSPLPPAVASRTASGRRH
SSIGSDPHNRVIVSSASNPAYETTAAGLVVEPVNTRANTLAISEGEGALGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSVTQAIRLWGTPKTVQDINNIFIRHIKGQLSAIPWSE
EELLPESNIIQQELVELNSRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVELFI
PSSDWAGLVARLNEVKDKTICFYAANAAGDFVSSDASGGLVLEGTEASTNAVTWGVFPGK
EIITPTIIEEVSFRAWADEAFKIWGEWAKVYGKGSESEALLERIRSEYWLVNIIHHDYIE
RDGLWKLLKGEKEH
>A0A4P7E070|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. CZ-2|TrEMBL
MKIVDHIKNANGKTLYSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYLYKQ
HSNGLLERVSYRKRPGTVAICAAIMSKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDSDFIPTPEGHAYAIDLLEQVADMNRGQYLHEDIGSSEKTDFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVTKCREHDIHVPIIPGLK
PLTTKNQLITLPRIFHLDIPEDLSDAVDACKTNAEVRQVGEEWLVQQCKELIEFGAPVLH
FYTMSNPGPTKKIVEKLV
>A0A1A8TEW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinomonas spartinae|TrEMBL
MKTQLATKFADPSRGVYFIGTTPPKSSVNNEQLAQISQKLLERLNGIDIDGLIVYDIQDE
SSRIDKPRPFPYLETHDPRAWSKRLKEASGSPVITYKSVSSRSCEEFSDWLQEAWDEFDI
RDIVLVGSPSSESNIKLPLSEAYLALQHAPQAFNLGGVTIAERHAKKKDEHIRLMNKSKA
GCEFFISQAVYNPQATADLISQYAQICKEQGVAPKRIILTFTPCGSAKTLEFMEWLGISV
PVATKNRILNSDAPLAESIKICRSALEQIIETALPDGVPLGLNIESLTNRKEEIDASIHL
YKLLKATLDLKLAEKEFADE
>A0A1C6RM40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora pallida|TrEMBL
MALGLPSVLPSSQPSIGELIRDCQPTFSFEFFPPKTPAGETLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGDPTGEWVAHPEGVRYAEDLVRLIRESGDFSVGVAAFPYRHPRSPDVASDTEYFVR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILPGVMPVTQLATIARSEQLSGAPF
PPALAERFERVGDDPEAVRQLGIEQASEMCRRLLDEGIPGIHFITLNRSTATREVWRNLQ
VGARV
>A0A2T0Q5Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. BL25I1N1|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLVTLKPKFVSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLDNFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCGRLIDAKVPGLHFYTLNGAAATKAICERLGA
>D5AJP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis (strain GZ1)|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINKNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A5B0VQA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter salinexigens|TrEMBL
MQSQTQFKRRFSFEFFPPKTDQGKEKLQGVRDQLAAVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRQEIGELLDLYKDNGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLQNFARKVKAGANSAITQYFFNPDSY
FYFVDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTQMCETLLKAGAPGLHFYTLNQVEPSLSIWKNLGISDREKIAF
>A0A7V6Y3Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterales bacterium|TrEMBL
MEKLNKFKESLLDKNIMSVTWELVPGRGANEKAQTDVILNAEKASKGGKIHALTLTDNPG
GNPAISPEILAAEIVNMGIEPLVHFTCKDKNSNQIESLLYALDRVGVRNLLVMTGDYIYS
GFFGKARPVFDLEPMHVLTMISAMNEGLEYKVPKGTVKHKPSDFFAGAVCSPFKKTEAEL
MCQYYKLKMKIASGAKFIVSQIGFDARKIHELIQFVKLNNWDIPLIGNIYVLTYGTAKLM
NQNKIPGCVVTDKLLAELEEESKAPDKGKEARLLRAAKMYAIMKGMGYAGVHIGGHGTKY
EDIEYIIDKGEELSKDWQSLISDFDYPMPNGFYYFEKDEKTGLNSDKITNRKGRPLDAKV
EFVYPLSNFVHELMLEPGTPFWKPMKAIAKMVDGTSLEKPFHFVEHLSKTILYDCKNCGD
CALPDLAYLCPMSQCPKNIRNGACGGSYDGWCEVYPGRKKCVYVRAYSRLKSRGKEHYLD
HEVIPPWKVELNQTSSWLNLYLGRDHNAKKYGIERVDKKP
>A0A285D069|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces microflavus|TrEMBL
MRELLATGETSFSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRAGTVRA
TQQIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVRYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDSDIGHFVDKCRAGADYAITQMFF
QPESYLQMRDRVVAAGCETPVIPEVMPLTSVKQLERFAQLSNASLPSALKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>K8DWV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforamulus hydrothermalis Lam5 = DSM 18033|TrEMBL
MKIAKLFATKQPVISFEIFPPKADTPVETIFTTLEGLIKLKPDFISVTYGAGGSSRSRTK
EIASRIKNHYRVETLAHLTCVGHEAGEIDMILQGLQEANIENVLALRGDPPADNPHYDFT
KGAFSFASDLISHIKKHNNFCIAAAAYPEGHAHCRRLSEDLNHLKYKVDQGVDFLITQLF
FDNRIFYNFMENARRIGIACPVMAGVMPVLNAKQIKRIISLCGASMPAKLLMMVDKYGDR
PEDMEKAGIEYASQQVLDLMENGVEGIHLYTMNKPRQITEILCNTGRVY
>A0A829S015|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 1130196|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A380WK91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter aminovorans|TrEMBL
MNQFPLSRRSDIGNKIRVSFEFFPPKNDDMEARLWETVTRLEPLRPQFVSVTYGAGGSTR
ERTARTVKRILEESTLTPAAHMTCVDATREEVDQVIAEFAAMGVKRFVALRGDPKEGVGA
AYQPHPGGYANGAELVGALKAQGDFDISVSAYPEKHPESPDFATDFDMLKRKVDNGATRA
VTQFFFDNDLYERYVERARKAGIYIPIVPGVLPIHSFTQVANFASRCGAHVPGWLAERFE
GLDRDPQTHALVASAVAVEQVLDLVERGVNDFHFYTMNRADLVVAVCHMIGIRPQPVVQG
SAAA
>A0A553IEP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylaria flabelliformis|TrEMBL
MHINDMIADAERTGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFVDITWGAGGRIA
ELTCDMVLQAQTFLGLETCMHLTCTDMGEEKVNDALQRAYRAGCTNILALRGDPPREQEK
WEATDGGFQYARDLVAHIRKKYGNHFSIGVAGYPEGCDDNKDEESLLDHLKEKVDMGGTF
IVTQMFYDADNFVRWVGKVRERGITVPIIPGIMPIATYASFIRRANHMNCKIPEKWMAVL
DPIKNDDSAVREVGKVLVAELCRQIMSAGIAHLHFYTMNLAQATRMVLEELDWLPSSQRP
RQQPLPWKQSLGFGRREEDVRPIFWRNRNKSYISRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNESNRKKWGEPQSISDIGSLFIRYLEKDLDSLPWSEAPLSGEAVSIKDDLIN
LNRRGFITINSQPAINGVKSTHPIYGWGPPNGFVYQKAYLELFVHPELYGEVIRRIESRE
ILSYYAVNQAGTFATNAPSEGPNAVTWGVFPGKEIVQPTIVESVSFLAWKDEAYRLGNDW
ARCHDANSPSRALIEGIMNKWYLINIGMHYSVARDQNHHSNGVLVNNDFNDTRTVFELFD
GLEIKDLNTPASVSAPHINGINGHKEAIGVTASN
>A0A0K9XH58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces caatingaensis|TrEMBL
MALGTASTRTDHARTVRDLLASGERSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSLAELRNVIGQYADVGIRNMLALR
GDPPGDPMGEWVRHPEGVDHAIELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFHAEDYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFAQLSNAAF
PAGLAERIRAVEDDPAAVRSIGIEYATELCARLMAEEIPGLHFITLNHSTATLEIYENLG
LHQRP
>A0A0Q1CI77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. ACN1ag|TrEMBL
MQESMAGHERPARGFELICEIEPPTRPDLTHARHQIGVLSPVTDAFLIPDNHIGRATVSS
IAVAHEVQTMGGRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVHGDKPTAGNRTSDL
TVRAMMDEARAASEDPAFADSPAFRVGAAAGLRPLPAWKRAADFLFVQVSYSVDALLRWR
DAHPVALPVYAGVMVLASAGMARRLAATIPDIDIPDDLVHAVERDQVAGVEAACDQVLRL
RDSGAFAGVHLVPVSRYRQVATRLEDLL
>A0A1V6P8A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium decumbens|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRALVDMALEEAKVLGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRKQHGDYFCIGVAAYPEGHPADAFQDVQDPMRDLPY
LIEKTVAGADFIMTQLTYDLEAYRKFETMLRTHESGVFKTIPIIPGLMPIHSYKILTRVT
KLSNVHIPDPIAKRMEELKHDDDAVKRAGVDVVSDIVGGIQELKSPGPRGFHFYTLNLEK
TVTFILERCDLIPPLSYIEDESAVEDVDVSVPLDTRARSLVGRRASSINSQPQNRVIVDK
LSGDGSSHDSVHEALATNAGLPAMPPGRGTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVTSAVARRLWGHPVEHSDINTIFRRHVTGELYMVPWSEGGAEEGGG
LNPETELIRPELLKLIDGRGWWTLASQPAVNGVRSDDKIFGWGPQREGFVFQKPFVEFFC
PDKDYKNILKPLFEKHGHDKLTWFATNQTGAFESSLPTQPADIDLDELDANPESVNAVTW
GVFRGKEILTPTIIEEVSFRAWGEEAFRIWDEWRRIYPHGSATERFLNTAKNEAWLVCVV
GQQFGAGTARGSKEEEDEVKWMWRVLAGEA
>T1BE38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
ASAAKLEEALPMLEKLHPTFTSITYGAGGSTREKTHDLVLRLKRDTSIEPMAHLTTAVHL
RSELTTILERYRSAGIENILALRGDPPLSGGGELPAGELAHAADLVALARSVGDFSVAVA
AHPEGHPDSPDLATDRMMLARKLELADMAITQFF
>R7N822|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:76|TrEMBL
MEKLKTYLEAHKLITDGAFGTYYSRVYDTNELPESVNITMGRRVTDIHKEYINAGAKLIR
TNTFAANTVNLECNFDEVKANIKAAVANARQAVKECGREVYIAADIGPIPNDNLFDKQAV
VDEYVDIAKVFLEEGINVFVFETFADLSNISDAIDYIGSAATGGINTADSVLTDRPFVIT
QFAINQFGYSNCGLSSSKLVKLADDNPYIDALGFNCGIGPGHMEQFILKERRHTDKYLSA
LPNAGYPQAVSGRMIFSDKNMDYYSDKMCELLNAGADIIGGCCGTTPDYIDRIASKADFT
QNRQGEGCDWETDNSVQAVNTAFYHNKEGKKLIAVELAPPFDSNADKLLDAAHYLKSKGV
DVLTFPDSPSGRTRADSILMAEKVSRQTGMCVMPHLCCRDKNAIAIRSQILGADINGINN
FLVITGDPIPSVMRSSVKSVFNFDSVGFMNILDDMNSEQFADQPVTYGGAINQGRKRLDI
EIGRVKKKMEAGATFFMTQPAFCDEDIERIATIKKETGARILCGIMPLVSFKNASFMKNE
MTGINVTDEVLLRYRPDMTKEEGEQAGIDLAVEIINKSIDIVDGYYFSFPFIRVHMLDKI
IKQSELYVNN
>G2SEH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermus marinus (strain SG0.5JP17-172)|TrEMBL
MKVIEILEQATGPLISYEIIPPRRGGSLEEVLAVVEELMPFDPPFIDVTSHAAEVEYEPL
PDGTLKPRIKRKRPGTIGICAAIKSRFGVETVPHLLCRGFTREETEDALIELHYLGIQNV
MALRGDSPNYQKPIPPDRTVNEYAVDLVRQIVNMNRGIYLEPLEDAVPTDFCIGVAGYPE
KHFEAPNLIWDIMNLKRKIEAGAHYVTTQMFFDNRHYFRFVERCREVGITVPIIPGLKIL
TSKRHLQLLPSRFHIEIPEELVAEVEAAKPEHVPEIGIAWARRQAEELLEAGVPCIHFYI
MLRADYVREVVAYLRKIA
>A0A1Q7QC02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_1_40CM_2_65_8|TrEMBL
MGLNDETSRQSLIGLLRAPRYEVLPTDDIEQLVLTHVPHDVTMTITASPRRGIDATISLA
ERLAKHGYHVVPHISARLIRDDAHLREVLARVDALGRGEVFVIAGDAKEPAGDFPDSVSL
LTAITAETHGLREIGVTGYPERHSFIEDDLTIQAMWDKRRIATYIVSNLCFDPRIVKKWV
ARVRRRGVQLPIHVGLAGVAEPAKLLRVSTRIGLADSARFLRGHSNWFMRMVQPGGYDPE
RFATGLLPDLAAPERRVVGLHFFTFNEIEATERWRQDALSRLLVA
>A0A4D7JMY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivirga pacifica|TrEMBL
MKVTEHFEKADKTLFTFEILPPLKGENIQKLYDHLDPLMEFKPPFIDVTYHREEFTYKKR
ENGLLERQIIRKRPGTVGICAAIKNKYNVDTVPHLICGGFSKEETENALIDLHFLGINNV
LVLRGDAMSSEPKFRAEENGHNFASELLEQVKNMNDGIYLDEDLTNAEHTDFCIGVAGYP
EKHFEAPNMATDLKYLKLKVDMGAQYIVTQMFFDNKKFIKFVEDCRKMDINVPIIPGLKP
ITTLNHLSSLPRHFYIDLPDDLVNEVEKCKNNTDVREVGVEWAIHQSKELLDFGVPSLHF
YSMGKAEPVRRIASALF
>H7GIZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus parvatiensis|TrEMBL
MKIRDLLKARRGPLFSFEFFPPKDPEGEEALFRTLEXLKAFRPAFVSITYGAMGSTRERS
VAWAQRIQSLGLNPLAHLTVAGQSRKEVAEVLHRFVESGVENLLALRGDPPRGERVFRPH
PEGFRYAAELVALIRERYGDRVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIEIPILPGIMPVTSYRQLRRFTEVCGASIPGPLLAKLERHQ
DDPKAVLEIGVEHAVRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGLRSASGQP
>A0A433IDM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Competibacteraceae bacterium|TrEMBL
MPAPSDGSPVLSCEFFPPVTAEGLIKLQAARSQLLALRPAYFSVTYGAGGSTRERTVEAV
LDIQHSGPVPAAPHLTCIAATRDSTRELLLHYRAQGIGRVVALRGDMPSGMRDPGEFRHA
NELVQFIRTEFGDHFHIEVAAYPEYHPQAPSPEKDLDNFQRKVDAGANSAITQYFYNADA
YFRFRDTCAQRGIAIPIVPGIMPITNFTQLARFSDACGAEIPRWVRKNLESFGDDREAIR
AFGLDVVSALCERLLSGGAPGLHFYSMNQATLTLAITERLGLIPARR
>A0A1W1H515|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfamplus magnetovallimortis|TrEMBL
MQFRKGFEADEFACLVQIEPPKGTDVSLMVKHAVNVKGVAHGFIVSEMGNAVMRMSSLGA
SLVLRENGLDAVLQVSCRDRNRLALQGDILAASACGINAVMVVAGEDPSFGDHHTAKAVH
DVTLDELLKGLAKMESGKDMAGIELSGSPDFLKGTTLNTCLRGADRENELDKMKRMIDAG
VSFFVTQPLFEFSMTQPFLKTAEKNGVKIIPTVLLLKSLGMARYMSRNVNSVNMPSAIVD
KIVSASDKVRECMKIARQLILDVKSEGYGGVNVSTLGWEDRLPEILGVMEGLKG
>A0A1X4NVB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marivita cryptomonadis|TrEMBL
MTAPTVSFEFFPPQSLEASFRLWDTVQVLAPLQPRFVSVTYGAGGTTRDLTREAVATLHK
SSGLPVAAHLTCVNATRAETLAIAQDFAAAGVTDIVALRGDPPKGSNGFVPHPDGFASSI
DLIEGLREAGDFNIRVGAYPDTHPEAADATADVSYLKRKFDAGASEALTQFFFEADTFFR
FRDACEKAGIDKPVTPGILPIENWKGAARFAQRCGTHIPAWVVDAFEKAERDGREDLLAT
AICAELCSDLIDGGVDTLHFYTLNRPELTRDVCHALGVTPKLTLKNVA
>A0A290XGV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas chenhongjianii|TrEMBL
MIPISFEFYPPKTDDQRTQLDRTVRKLAAHAPEYVTCTFGAGGSTLSHTPVTVRRLNQEH
RLDAAPHLSCVGGSREEIRELLELYRAMGCNRIVALRGDLPSGMGHPGDLRYASELVAFI
RSEFGDRFRIEVGCYPEIHPQADDARADLGHFKAKVDAGADAAITQYFYNADAYFHFVDS
ARRAGVEVPIIPGVMPISNFSQLRRFSEGCGAEIPRWMLRQMSAYGDDVDAIRELAVDIV
TRLCERLIAGGAPALHFYTLNLARPTQAVLARLS
>A0A7K5G9Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chunga burmeisteri|TrEMBL
MVNETQHTCSASSSSKSDGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVMALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7H1DU87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium manosquense|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHVLCGGFSQEETEYLLVDCMYLGIDN
VMALRGDAMKGEQHFVPTVGGHRNAMDLVHQMNDLGRGKYLHDEKISAEENKFCIGVAGY
PEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIDFVKQAREIGINVPIIPGIK
PIATKGHLQMLPKVFKIDLPEDLISEVEKAKDNTAVKQIGIEWAIAQCRELMDFGVPVLH
FYSMGKSDNIKKIAKEIF
>A0A3Q8YRD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQSARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPEAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQVVAERLDHILHDEITETQVDMVK
TAH
>L7WAQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonlabens dokdonensis (strain DSM 17205 / KCTC 12402 / DSW-6)|TrEMBL
MKITKHIQKATKPLFSFEIIPPVKGKSIKQLYDNIDPLMEFKPPFIDVTTSREEFIYLEK
ENGLLEKRLTRMRPGTLGICASIQNRYHVDTVPHLLCGGFTKQETEYLLVDCQYLGIDNV
MALRGDARKEERRFEKTTDGHEYAIDLVKQIQKLNEGSYLHEVIEITCDVDFCIGVAGYP
EKHEESPSMKSDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVKCARAAGIQVPIIPGIKP
LATKKHLNLLPQTFNLDLPETLVEAVESCKNNKEVRQVGVEFCIEQCKELLAHDVPVLHF
YSMGKSDNIESIARAIF
>A0A2T5J2I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agitococcus lubricus|TrEMBL
MPRQIPISFEFFPTKTEEGTQKLLHVHQRLATLNPAYFSVTYGAGGSTRERTLSIVDNIQ
QAAPIPVAPHLSCIGDNKSEIAELLHRYKNQGIKHLVALRGDLPSGQMGLGELPYARDLV
EFVRQETGDHFHIEVAAYPEMHPQSYDFDSDVKNFIAKVNAGANSAITQFFFNADAYFYF
VEKVRKAGVTIPIVPGIMPITNASNLIRFADGCGADIPRWIRKQLAAYGDDSASIKAFGE
DVVAKLCETLLQGGAPSLHFYTMNQAEPTTRLCQLLDLA
>A0A1C5RAU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Eubacterium sp|TrEMBL
MRIPELFDQKRPVFSMEIFPPKKKANIESIYDTVEKITVCKPDFISVTYGAGGSMTDNYT
CEIASNIKKKFGIETLAHLTCINSSREDVKEMIGRFQDADIKNILTLRGDIAEDCDIKKD
FHHANELAIEVQRKCSDDLEILGACYPEGHYESKSLDEDIQNLKYKIGAGVKVLISQLFF
DNQLFYEFMGKARMMGINVPVSAGIMPITNARQIQRTVALSGASLPHDFTKMIGLYENKP
EELFEAGIEYAANQIRDLITNGVDGIHLYIMNNADVALKVYENIKDLL
>A0A1F4HAH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_66_14|TrEMBL
MLAAAAPDRQAVKSGSGLERVLAQGDFAVTAELGPPRGWHPDSVKRKAQLLKGWVHAANV
TDNQAAVVRMSSIATGLIMIDEGLEPIVQMTCRDRNRLAMQSDLLGAAAHGVRNVLCLSG
DHQSFGDHPGAKNVHDIDSIQMLAMLRAMRDEGRFQSGGEIAEGGPQFFIGAAENPFADP
AAMRPYRLRKKAAAGAQFIQTQLIYDLARFREFMKKVVELGVHEKVSILAGVGPLKSPGM
ARYLREKVPGMSVPRSLDARLEGAAEGIDAGDKQALNRAWREEGKRICIELIREVREIEG
VAGVHIMAIEWEQAVPEIVKAAGLMPGAPA
>A0A1B8RPF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium paraputrificum|TrEMBL
MNIKELFENKKVVFSFEIFPPKTTSSIETIYKTLDSLKGLSPDYMSITFGAGGSVQDNRT
IELSSLVKNKYGIEAVAHLTCISSTKNEIEYYLEKLKENNIENILGLRGDVPADGKIIGE
FNHANELIDFINQKGKFNIAAACYPEGHIEHKGLYREIESMKRKEEAGASYFISQLFFDN
NLFYNFKDEVRAANIKLPIEAGIMPVTNKKQIERMVALSGASFPDKFKRIIERYEHNPEA
LRDAGIAYAVEQIVDLVSTGVEGIHLYVMNNPYVAEKISGSVGRIIESINKVELV
>A0A1C3HKM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia marcescens|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASLAQLRDIATDYWNSGIRHIVALRGD
LPPGGGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A2H6B7X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR41|TrEMBL
MRIDQILRERRPVFSFEFFPPRTDEGQRQLEETITVLQADRPDFVSVTYGAGGSTRERTV
EVTKWMKQDLGIEAMAHLSCVGEPVSRLREILDELEQAGIENILALRGDPPRGETEWRPH
PQGLRYSVELIRLITSNYDFCVGAACFPEVHPEAESLEEDLRYARQKVEAGASFLITQLF
FDNALYFDFVDEARAHGIDVPIIPGIMPITNYKQIKTITGMCGASIPRSLERELRARSDD
PEAVAELGVAYATLQCADLLARGAPGIHFYTLNRSTATRAILAALRAAHPWTRAETVV
>A0A2T0S9L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudosporangium ferrugineum|TrEMBL
MPPKTREAEQLLWRTIRELEPLRPDFVSITYGAGGTTRDTTVEVTERVATETTLLPMAHL
TAVNHSVAELRNVVGRLAGAGIRNVLAVRGDPPGDPNGEWVRHPEGVLYAEDLVRLLRDA
GDFSVGVAAFPYKHPRSPDIESDTRNFIAKCRAGADFAITQMFFEADDYLRLRDRVAAAG
CDTPIVPGVMPVLRMATIARSAQLSGAPFPPDLLARFERIADDEAGVRKLGIELCGEMCR
RLLDEGVPGIHFITMNRSPATREVWQQLTGVNAAPAAA
>A0A3A4ZAC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MVSSFKKVLESGKFVVTSEIAPPKGTNLDRMKHHIELLRDKVDALNVTDHQSSVMRFPSL
GGAILVKEMGGEPILQMTCRDRNRLALQADLLCAASRGVNNVLCLTGDSVILGDHKEAKA
VFDLDSSQLLAAIRRLEKGKDLGGNDLDGGVSFCAGAIVTPEANPIEPQLIKFEKKVEAG
AEFIQTQAVYDLDGFKKFMEYARNFDVKILAGIILLTSAAMARFMNKNVAGVNVPQALID
EMAGAPKGKAIQKGIEIAGRMISRIRNERMCDGVHIMAIGKEELVPEIMTAAGLI
>A0A137Y987|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter venetianus|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIKRFVEKVQAGANAGITQFFFNPDAYFYFI
DRLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A7C1DJK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MVSAFKKALESGRFVVTSEVAPPKGTNLEEMARNVELLKDKVDALNLTDHQSSVMRFPSL
GGSLLVKEMGGEPILQMTCRDRNRLALQADLMFASSRGINNVLCLTGDSVMLGDHKEAKG
VFDLDSSQLLAVVRTMERGKDLSGGELNGRVRFCAGAIVTPEADPIEPQLIKFEKKIEAG
AEFIQTQAVYDLDNFKRFMDYARRFNVKILAGIILLTSAAMARFMNKNVAGVFVPQSLID
EMAAVPKGGALKKGVEIAGRMISRIKEERICDGVHIMAIGREEMVPEIIEAGGLS
>A0A073JX16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus manliponensis|TrEMBL
MKLLDLLNKGIVIGDGAVGTLLHSHGLQSCFEELNLSDPNRIVSIHKQYVAAGADIIQTN
TYGANEGKLRMYGLENKVEKINKEAVKLAKAAVKERNAVVGTIGGMKHLGAITTTDTERE
FMLLEQANALLEEGVDGLLLETFYDEFELLHAVKTLRKQTNIPLIAQLALHEVGTTQNGN
YIDDILQQLIHVGANVVGLNCQLGPLHMIESLKMISIPKSGFISAYPNAGLPKYVEGRYE
YEGSVAYFEETAPKFIEEGVRLLGGCCGTRPAHIEAIKRALEKKVPITEKQVAERPKIVT
PQRSNVVNRITLAEKAKKETTIVVELDPPKTLDTNRFFEGAKALKRAGTDAITLADNSLA
SPRISNMAMGSLLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSTLGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIQEMNNGRSIMGKSIGPATSFSIGAAFNPNVKKLNAAVKRM
ERKIAAGATYFLTQPVYDVALIEKIYEETKHLEEPIFIGIMPLISKRNADFLHYEVPGIT
LPEEVRQRMDGHETKESAVQEGIRIAEELIDVTMKYFNGIYLITPFLRYEVTASLVKYVK
RKQKEKEGIYA
>A0A7T7KMZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Martelella lutilitoris|TrEMBL
MSESTEPLGRKREIDFSFEFFPPKTAEAEAGWWRSVEELAAYEPGFVSVTYGAGATSQAP
TYAAVKRLVDETRLQTASHLTVVKAGKEEVDDVIRRFRDAGIRRFVALRGDPPGGIGTAY
SPHPGGYANAAALVSALKAIDDFDISVSAYPEKHPESADRAADVAMLKAKAENGADRALT
QFFFDNDVFEDYLNDVRRAGIAIPVVPGIMPIQNLAQLKRFAAMCGASVPAFVERRFEGL
DDDPDGRFEAAADLAAEQVQDLVARGVADFHFYTMNKSKLMTAVLDRLGIKPGDTLSDAV
PERMRA
>A0A848CIA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio piger|TrEMBL
MQIAQALRQTTKPFVSLEFFPPAAESHLPEFYETVERLRSIDPLFLSVTYGAGGGKQQNT
LNVTAELARRGFTVMAHLTCVGAEPQAISDFVSHLRAAGVHNVLALRGDAPRGVSDWDWN
AGHFHNARDLVRFLRSEHPDLGIGVAGYPAPHPDAATFASDRAYLADKLRAGADFVITQL
FFDVREYESLVSSLRAAGLETPVIPGILPIQSFDSLRRVLSLCGANIPGKLYLELEAAHN
EGGVEAVREAGLRFAARQIRQLLDCGAPGIHLYSLNKSEMCLRLVEEAGL
>A0A7C0Z3A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MELRNRFNVGEFVVLVELVPPKGVDISGMLKVAGKIRDKVTAFVVPDMAAAVMRMSALGA
AMILQQKGFKTVMQVCCRDRNRLALQGDLLAAYAGGITSLMAVAGEDLRYGDHHEAAAVD
DLDLIGLIEAVGTMRGGKDLSGAELAGEPRFFCGTTVNVGLGDADLAAEVAEMNRRATAG
AEFFVTTPVFDPAAIEPFRQLMDIRKQNVVPTVMLLKSIGMARYIQRNMAHIQVSDEIIS
RLQKAPDKTKESLRIARETIAALCEANFKGVLISPMGWEENLPELFEQVE
>A0A7I6QGY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella sp. WP3-W18-ESBL-02|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7W0EUP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLEKILQAGHFAFTGELGPPRGANVEAVKEKAKHLVGCVDMVNITDNQTAMVRMS
SWAASLIAIEAGLEPNYQMVCRDRNRLAMQSDILGAYALGIRNILCLSGDHMQFGDHPHA
KGVFDIDSIQLVSTIKKMRDEGKFLGGEVIDTPPKMFIGAAANPFADPFEWRVYRLAKKV
KAGADFVQTQCIFNMEKMREWVKRSNDMGLTENVAILAGVTPMKSLGMARYMKRNVPGMD
VPDYVIKRLQGVEKNKQADEGIKMACEQIEEFKEMKGVAGIHLMAIEWEHMVPEIAERAK
MLPRPKV
>A0A8J3K038|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catellatospora chokoriensis|TrEMBL
MTLRAPSTMPGPRPTVRELLTSGEPTFSFEFFPPKTADGERVLWQSIRELESLQPSFVSI
TYGAGGSTRDTTVQLTERIATETTLLPLGHLTAVNHSVGELRNVIGHYSDAGVRNMLALR
GDPPGSDPQAEWVAHPQGLHYAEELVRLLKDSGDYCVGVAAFPEKHPRSADFASDVHHFV
RKCRAGADYAITQFFFDWQDWARLRDAAAAAGCDVPIIPGVMPVTNVSQIERMAQLSGAA
FPPDLAERLRAVADDPQAVRAVGVEVATELSTKLLAEGAPGLHFITLNRSTATREVWQRL
RVGAAV
>B3CIB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides intestinalis DSM 17393|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNRYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELTCEAMKCKTDEEAKQVGIEWCVKQCKELMEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A285NMP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohaesibacter gelatinilyticus|TrEMBL
MAVAREPISCPVKCGEMMNHNTERSGRRSQDADKLKISFEFFPPKSEKMEENLWASVERL
APLSPSFISVTYGAGGSTRERTHDIVARMVEETKVKPAAHLTCVGATKQEVNDVIRSYAD
CGVNHIVALRGDPVDGVGSRYEPHTGGYVNAADLVSGIREIGDFEVTVSAYPEKHPESPD
FAMDIEMLRQKVDAGATRAITQFFFDNDLYEAYVERVRRAGIFIPIVPGILPIHNFKQMA
NFASRTGASVPQWLANRFEGLDDDPETHRLVAAAIAAEQVQDLLERGIDDFHFYTMNRAN
LSYAICHLLGLRPDGA
>A0A1Q9QN23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum sulfidophilum|TrEMBL
MTAPRVSFEFFPPQTLEASFRLWEAAQALAALKPAFVSVTYGAGGTTRKLTHEAVQTIHN
HYGLNVAAHLTCVDATRAETLEIAEAYSAAGVSEIVALRGDPPKGQGAFRPHPDGFANSC
ELIEALAATGRFRLRVGAYPDPHPEAGAPDADVRWLKRKFEAGADTAITQFFFEAETFFR
FRDACEKQGIDGAKIIPGVLPIEKWVGVRRFAQRCGAHVPAHVDEAFETAIRDGREELLG
KAMATELCTELMEGGVRDFHFYTLNKPHLTRDICHALGVLPDAHLEKVA
>A0A3A5AA77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSETKTPSKLEKRLRAGHLAVTSECGPPRGSDAKAITAKAEMIRNYVDAINITDNQTSVT
RLCSLASCIHLKLMGVEPILQMVTRDRNRIALQSDILGAASFDIHNILCLSGDHQSFGDN
PRGQNVFDLDSMQLIQTVRHMRDEGKFLGGDPIQRPPRMFVGAAANPFADPFEIRVPRLA
KKVAAGVEFIQTQCIYNLDKFELWMKLARERGLHEKVYILAGVTPLKSAGMAKYMKNRVP
GMDVPDDIVKRMSGVAKEKQAEEGIKICVESIQRLKEIEGVRGFHIMAIEWEEKVPEIVQ
KSGLYPRPKID
>A0A3N5J1A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MTFGLRRRIKPMPPTRGDLNPMPKSFQEALKSGKFLVTVELDPPKGVDSGELVRQVQTLK
DRVDGINLSDNRGGVMRMSALAACLLTKQAGGEPILNLACRDKNRMALASEALGAAGLGV
SNLLCMTGDHTTHGDHKESKPVYDLDSVQALKMLKGMMGGKDLNGNALKGAPTYCLGGVV
TPGADPLEPQLLKFTKKAEIGLDFFQTQAVFELDRLK
>A0A3A4XMA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKLKDALGHSKFVVTSEVQTPLGEDSPEQLVDRLKRIRGRVDGVSVSDVDLEGVVGDSIR
TCELLQHHRFNAIYQTTTRDKNRIQLQKDLTQAHESGIENLLVFTEDYRISGDSVQEHMF
FHVDAGKLGSVLEHIRNGRKIEGEPMPEPFDFTLGSGIESLWGKKVPKQGMQGMETMKLM
GAGYFLTTPVFDLEQFDKFMRQVKILGVPVIAEVLLLRNAAMARFINRHFKQGLVPDWVV
QKLDKAADKRQASIELFGDLARGLREICQGLHIITLGGEDKLQPYLDAANLR
>W9EG40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructilactobacillus florum 8D|TrEMBL
MAEHQPSFSLELTPLGGNSEQQALLQSLPSWGALQPDFISITAHGGVERAYGAGFELATA
VQQDLQIPALVHIAGQTWSPTTLKPYLEKLRAAELRHVLTIRGDEVFKNAEQQNFTTAAN
LAAFIRRVGGFDISGACYPHLYHMPPTELPDDLHLLQAKLSSGMTRLITQLFFDNEVFFA
WQRRVRSIGIGVPILAGIFPVTSLQQKSRLKQLAGGSLPDQLNDQLADVANDPAAVQAVG
IDYAVNQIKDLLARGVDGIHLYTMNNLEVTQKIYQKTQAWFNKSK
>A0A1B9I3D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kwoniella pini CBS 10737|TrEMBL
MKITEKLQKAEKEGRTFWSFEFFPPRTAQGLQNLYDRIERMRNLGPEFIDITWGAGGKNA
DLTSSLVQVCQETIGIETCMHLCCTEMPKEKVEWALAQAKQHGCQNILALRGDPVAGTSK
WEPTPGGFTNAVDLVKHIHENYPGDFCVAVAGFPQGHPETPEGEDAATQEIRWLKEKVDA
GAEFIFTQLFYDVNIFFNWVKRVRAAGIEVPIVPGIMPIQNWEKFEKWVARENIIVPQHF
YDALKPVKGDDEKVRQVGTKLVAQMCKEILANEEAGIKGLHIYTLNLEKGARMLLQELGL
EGRREQIAPLPWRPSLTPHRRAESIRPIFWANRVQSYLSRTDEWDEFPNGRWGDSRSPAY
GDLDGYPVSININANDAYNLWGHPETFSDISNLFAKFCRGDLNKLPWSSQPPASETSVID
EQLAKMNELGYLTINSQPAVDGVPSDDKVHGWGPSGGYVYQKAYLEFFVSPELLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWANLYPPSSPSRNLIESTMNTSYLVNIVANDFRDGMSIFEPFMLNQSTVGKVIEGT
SQTVNGIYEVAKEGLNGLVENVKQQINGQSNGNAIATNGH
>A0A523YL63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MAASFKKTLKSGKFVVTSEVAPPKGINLEKMIHHIELLKDKVDAINVTDHQSSVMRFPSL
GGALLIKEMGGEPILQMTCRDRNRMALQADLFFAASRGINNVLCLTGDSVILGDHKEAKG
VFDLDSSQLLAAIRRLEKGKDLGGNDVDGSVSFCAGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVYDLDNFKQFMDYARQFPVKILAGIILLTSAPMARFMNKNVAGVSVPQELID
EMASAPKGRAIGKGIEIAGRMIRRVCDEKMCDGVHIMAIGKEELVPDIMAAAGLD
>A0A5C4JNY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Martelella lutilitoris|TrEMBL
MSDSNETRGRQRQIHFSFEFFPPKSVDAEASWWRSVEELSAYDPGFVSVTYGAGATSQTP
TYAAVKRLVDETRLATASHLTVVKASKGEVDDVIRRFRDAGIRRFVALRGDPPGGIGTAY
SPHPGGYANAAALVSALKAIDQDFDISVSAYPEKHPESADRTADIAMLKAKADNGADRAL
TQFFFDNDVFEDYLNEVRRAGITIPVVPGIMPIQNLAQLKRFAAMCGASVPAFVERRFEG
LDDDPEGRFEAAADLAAEQVQDLVARGVGDFHFYTMNKSKLMAAVLDRLGIRPGRALADA
VPERLRA
>A0A523YF39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSEYKSGSNLEKVLKAGHFAFTGECGPPLGANVEHLKEKAGHLKGCVDAVNVTDNQTAVV
RMSSWAASLILLQEGLEPNFQMVCRDRNRLAIQSDILGVYSHGIRNMLCLSGDHQRFGNH
PEAKNVFDIDSMQLIHTVKTMRDEGTFLNGQDIDVPPQLFIGAASNPFAEPFEFRVHRLA
KKIAAGADFVQTQCIYNMDR
>A0A318R2Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus XMU1408|TrEMBL
MKSKLQNRLESGLSAITAEIMPPRGGNTALALSKALTLNKLVHGFNVTDGSRAIMRMSSL
ALCKLLLEANLEPVLQLSCRDRNRIALQAELLGAHALGIKNILCLTGDPVRVGDQSQAKS
VQDFNSIELIDQVTSLNKGIDPVSGFLPDGPTNLFPGAAADPNCRGFDGLRRRIELKKNA
GANFLQTQMVMDPKVLERFCKEITEPMKIPVLAGVFLLKSAKNAQFINRVVPGACIPPSI
ISRLESSSNPINEGISIAGEQVKSFLEIAQGVHLMAVKAEEQIPMILDKANINY
>J3CEK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium sp. YR531|TrEMBL
MSFFRQSRRADLGNNIRVSFEFFPPKTEVMEERLWETVTRLAPLNPEFVSVTYGAGGSTR
ERTARTIKRILTETDVNAAAHLTCVDATKEEVDTVVREFAAMGVNRFVALRGDPASGVGA
HYKPTPGGYENGAELVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDQYERYVEKVRRAGIYIPILPGILPIHNFTQVTNFCSKAGTHIPAWLAERFD
GLQNDEQTHALVASAVAAEQVLDLVERGVQDFHFYTMNRADLAFAICHLIGIRPDNGALQ
PNLAGAAA
>A0A101K166|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. WAO|TrEMBL
MMNAFRPSRHGSRRPRVSFEFFPPKNEEMEVSLWESVRRLEPLGPAFVSVTYGAGGSTRE
RTHNTVKRMVDETGLKPAAHLTCVSASCEEVDDVIRAYWAAGVRHIVALRGDPAGGLGTV
YEPHPQGYHQTSDLVAGIRKVGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAI
SQFFFDNDVYFRYLDKVRARGIEIPILPGIVPVQNFRQTAGFARKTGASVPQWLADRFEG
LEDDPATRRLVAAAVCAEQVLDLVDRGVSDLHFYTMNKADLVYAICHLVGLKPEKVQAQQ
VAAE
>A0A8C3EEZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corvus moneduloides|TrEMBL
RPSPNSHGHPGLLSCNQGKSDVDLTLLRARFDPAGTRGAASNSRSDGGSSSGSESSKDNS
RCSTPVLDADRHERLRDKMRRRQDAGDKWFSLEFFPPRTANAAVNLISRFDRMGAGGPLF
IDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDITGHLQKAKRLGL
KNIMALRGDPAGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYEAD
LRHLKEKVFAGADFVITQLFFRPETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVK
LSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATT
EVLKRLGLWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWG
NSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTCEESVFEVFTCYITGEPNRNGYKV
TCMPWNDDPLATETNLLKDQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQK
AYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREII
QPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLEN
CLWQVVEDTFELLNSPTQQ
>A0A2R8CJ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kushneria phyllosphaerae|TrEMBL
MLREALCQQRFICVVEFVPGLSGERCAVFESMMQRAQLCGWPMVAAVADRVSSSQDLSPL
AAYSRLAHSLPTLLHFSGKARERHDLLKQLEQMDAAGLDQLLLLSGDRLPGHEPGQPVRY
LESVPALQIVRQARPNWLLGAALNPFKYHEEESGAQYFKAEKKLAAGADFLTLQLGFDMQ
KHREAFQWMQQRATPVLLLACVMPLTFKTATFLEQVPGVVISPSMRDLLAAEEAISRSHA
RERSLFRLGLQVIGLRLMGYAGIHLSGIHTPAQLQALEKVIHAQQEGIQTLAQWSAAWEA
SWQMPGLPTVIFHPEHADWRMGQSSVHATSREQYRYHVLSAVHTLLFSRKNPISRGFGWL
CRRPVWRTPRGARWLHQLERRLKGPVVGCDTCGNCRLEDTLYVCPETCPKGLANGPCGGT
RLNRCEFGDRECIHSVKYRTARTTQQTHVLTDRLIPCVDADARHQSSWPRWFTPPQKEER
HGKPRSSDADAMEKIE
>A0A378WRJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia africana|TrEMBL
MHGSGPSRSGGWTGADPGRAACREGASYYTGPVSFDNVRGRSTPGRPSRTPSATPSVVGQ
LGRRPDGTIPFSVEFNPPRDAAAEARLWRAAREFERMHPAFVSMTYGAGGSTRDRTARIT
GQLARDTTLLTVAHLTAVGHSVAELRSIVGSYADAGIRNMLVLRGDPPGDPLGEWRKHPD
GVEYAEELVRMVCELGDFHVGVASFPQGHYRSPDLDHDTRYLVSKLRAGAEYSITQMFFD
VEHYLRLRDRVAAYDAEQGAKPIIPELMPITSLRTVQRAEELSGRPLPPRIMQRLEQAAG
TDPEANRNAVRAVGIEIATEIGQRLIDEGAPCLHFITLNFAKATTEVLTNLGYTVTPAAA
VNA
>A0A286HPX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea halophila|TrEMBL
MTQPDTNPHDPSALLEPLPGHSSLGRLERILRRGEFAVTAELNPPDSANPHDVYERAAIF
DGWVDGINAVDASGANAHMSSVGICALLTRMGYAPILQISCRDKNRIAIQGDVLGASAMG
VQNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRIMRDNSKFLSGRKLTSPPTVFLGA
AINPFAPPHDFRPHRLAKKIAAGAQFVQSQYCYDVPMFRKYMQQVRDMGLDKECFIMCGV
GPLASAKTAKWMRSNVPGVHIPDDVIKRLEGAADQKQEGKRLCIDIINEVKEIEGVSGIH
VMAYRQEEFVAEIVHESGVLKGRRPWRKEPNPVDQLVAERLEEILEKPKHLLHEMAGAAG
DSDTQE
>A0A2N5E0D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chimaeribacter californicus|TrEMBL
MSFFHANQRDALNQSLAELHGQFNVSFEFFPPRTSEMEDTLWRSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRQIAHDYWHSGIRHIVALRGD
LPPGSGKPEMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPQWMISMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGIRPGTAAPV
HA
>A0A2D5VBV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MSXFLPQLESQILVCDGGFGTQLRQRIPSXIDCLDACNVEESYQELVRQIHLEYCQSGAD
XIQTNTYGANQRKXELYGFGDRVKEINQVGVELAKQAVAKXRMLSLSHDSREIFVAGSVG
PLESNPFERDLSVSEMRQIFKTQITVLVEAGVDLVILETFTNLHQATVAVKLALEFEVPV
IAQISGVSKGLLRDGTDVRVFAQSLAQLGVSIIGLNCRGPHDLLXATEXLAPVISTPLSI
QPNAGTPRIDQGQLDTTYSVSADLFNEYVQKFIDLGVNIIGGCCGTTPEXXRKXRSSVAG
QSPIQRPTQIFVFPEQPKXPKGIVPPNPIQQIFEXKNRIVSVEMRANTFPQLKAMLNQAQ
RLATVGVDMFDVPDNAGATVNIGTIGTAFRLQQVTNIPTLIHWTTRQRNLISIQSHLLEA
WALGIQGVIALSGDHPKVGRYETAKVVTDLRGSVQLMALIERLNQGYLIDGSPLGEACNF
YVGGGLTVAPNLSPHLKHLRQKVENGARYVYTQPVYTLDDAEQIYHATRNFGIKVLLGIL
PITSFRSISFLRDNLGMYIPLTVVDRFQSLSSXEDQAXYGLEMINDFVYQLSRQDRFPVD
GIYVIPPARINWKRKQAXISQLIRTFRSQV
>A0A1D3TP39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobium acetethylicum|TrEMBL
MGIREYLKTKKLIADGAFGTYFSQINNTNETISERANLTNPELVLRIHSEYIKSGARLIR
TNTFAANTRILGGTAAERDEIIRSGYRLAWEAVNRSGCKVFVAADIGPIPEDLHSEPAEI
MDEYLRICDCFLECGAEVFVFETFPNVNYIKKIVKYIKEKNKDAFIITQFCINRYGYTKS
GISASRLFAKAGSIEEIDAVGFNCGIGPSHLYQVLKKMKFETGKYVSAMPNSSYPEMLQD
RMVYLDNIQYFGEKMQSISELGVSILGGCCGTTPLYIEETMKRIDFSPVDIGKMHMDREK
TEPEAAVNNKFYRKLLNGEKVIAVELDPPYDAKVEKIMECANILKAGNVDILTFADSPMG
RGRVDSILMSAKVGNEVGIPVMPHIACRDKNVIAMRAGILGGYINNIRNLLIVTGDPIPS
GDRDETTSVFDFNSVKLMEFVKEMNVEHFSEEPIVYGGALNHGRANIDKEIERMQKKIEA
GASYFLTQPIFSDEDVDRIHYIKSRVDTKILCGIMPLISYRNASFIKNEIAGIHVPKEIV
DRYSPDMTREEGEATGVAIAREVMAKLGDVADGFYFMLPFNRVHLVEGMLKNEQKSRL
>A0A2T4UG35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Conexibacter sp. Seoho-28|TrEMBL
MTDPAQQLLLLVAEQLERRRVGELHPPVRVDDVHRVRDARQERLEDVARREPQALADPLH
RARRHAPIVAHRARPRAGPAVESSGRRARPRGADVGSAGAPPSGHAAHGRRETTVGPRHR
GPRQDRASLAVGPARPQDPGVSRFADALAARTLLSAELTPPLGADPTAALDVARTWAGCD
LDAAQVNDHLCARVRMSGVALAALLRGTRLETVLHVGVRHRNRIAVQADLLGAHAIGVRD
LVVVPGHDVRLGPDPHAREARDLKTSAAIALVRRLADEGRLSSGYRLAGPLRFRVGAVEA
VGRGSTDELRRRIDAKAQAGAHFLQLQGLTDADRATAVLDALWADGVPERVALVASIVPV
RDAAHRAQLARIPGVAGVDAEGSTAAAELGRLLLTHRATSGLHLRPLLWEDAVPPLVAAV
RAR
>A0A7C3YU12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MATPLKEVLKSGKFVITAEVGPPKGTNIETMLHHIDLLKDKVDALNATDNQSSVMRYPSL
ATTFLIKERGGEPVLQMTGRDRNRLALQSDLLAAYTRGVQNVVCLTGDSIRVGDHKQAKA
VFDLDSVQIIKMVRQLETGKDMGGNDLDGAVEFCVGATVTPEADPIEPQLIKFEKKIEAG
AEFFQTQAIYDLVKFREFMKFARQFNVKILAGIVLLTSAGMAKYMNANVPGVFVPQELID
ELSAVPKGKGLALQKGIEIAGRMIKEIKDDKICDGVHIMAIGKEDLVPDILSSAGL
>A0A2D5VES4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MGTWQKPSFRSLLEETDTFITCVEMVNSRGVIAEREGTRLLKLARELAQNPRIHALCVTD
NAGGNAMLSGETLGTDLISRGQEVVIHLSCKDRNRNGLQSQAWKLASEGFNNVLALSGDY
PVNGYQGQASAVFDIDSVGLLKIMSEMNAGLKIVAGQKKKDQVLKQTSFFLGAVVNNHKQ
YEHEVMPQYFKLKKKIENGASFIINQIGYDARKQDELLKYMDWSGLHVSVLANVYVLSLT
XARFFHANNIPGVTVTDDLLAXVEXXAGSXDXGKXFFLEFAAKQCAIAKGLGFRGVYLGG
XLKSSDYXRIXEIADQFGEXDWKDFSKXXCFHQTXEFYFFEPXTSTQLSSTEINRXYLHS
KXLKALQXSKQNIPLXYKINRVVHDKAFEKGTLGXGLGKKTSQAIXRTXXGVXKIXHGLE
XTFKXAAFDXQDCGDCSLPDIAFLCPESQCAKNQRNGPCGGTNQGKCEVGEKECIWSLAY
GRLKAYGQEEQMLNGPVIFKDGSLKGTSAWINTFLERDHHGDSRKQMEN
>A0A1S7NZB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium deltaense Zutra 3/1|TrEMBL
MAPGGHDMLRSETARRDGDIRLSFEFFPPKNPEMETQLWETVAELKKWNPDFVSVTYGAG
GSTKAPTLDAVRRMIGDSHLATAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPST
GIGTAYKPHPEGYENAAALVKGLREIADFEISVSAYPEKHPESASEAVDIDMLKRKADNG
ATRALTQFFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLD
ERFEGYDDDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLR
RSAA
>A0A0F5APN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinivibrio sp. KP-1|TrEMBL
MSYTHAGHIDALNQNIADLDGDINVSFEFFPPSTPSMEETLWNSVHRLKALKPKFMSVTY
GANSGERDRTHDIVKSIHDQTGIAAAPHLTCIDATEDELRHIARDYWQNGIRDIVALRGD
LPSPEKKPDMYAVDLVRLLKEEHDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAKMTNVRVPQWMHKQYQ
GLEDDPVTRQMVGASIALDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPLAVTP
>K8P293|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afipia clevelandensis ATCC 49720|TrEMBL
MTSDTAAPAEPHGHKRPAISFEFFPPKTEDMERGLWEVINRLAPLTPNFVSVTYGAGGST
RERTHATIARILAETKLTPAAHLTCVAASKADIDDVVARYHDVGVRHIVALRGDPTSGIG
TQYTAHPDGYQQSSDLVAAIKRNHPDMEVSVSAYPEKHPESASLDADIDALKAKVDAGAT
RAITQFFFDNDLYYHYLDRVRAAGITIPIVPGILPVQNFKLAKNFATRAGATIPDWLEAK
FEGLDDDADTRRLVAATVAAGQVQKLAKQGVENFHFYTMNRADLVFAISHLLGIRPAGAQ
KAA
>A0A434TK39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1A.F.Ca.ET.072.01.1.1|TrEMBL
MSIRHQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVF
LGAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>A0A067NYQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pleurotus ostreatus PC15|TrEMBL
MKLSEKIASYTSSRPFYTFEFFPPRTDQGFENLVPRITRMAGLNPLAVSVTWGAGGSTKD
RSLELAGIVQREHCVDTILHLTCTNMEKGLVDEALRAAKDRGIQNILALRGDPPRGEEDW
IATDDRFTNGKNLVSYIRSTPEFASDFAIGVAAYPDGHPESSLTEEEEIANLKDKVDAGA
DFIITQLFYDVDGFLRWLQKVRDAGITVPVIPGIMPIQTYASFQRLIKLCGSRVPPSIMA
ELEPISNDDQRVKNYGVSLAVSMLRKLSASGIKGFHFCTLNLEKSIQRVLETLKWTGPST
LEQNKLIVDSELTVSPHNATGSAKMHLMNLPEVEGEAGKGELNNAATWDDFPNGRFGDFK
SPAYGDQGPWGGLLISRNEALIQWGRPKSVQDLTKLFVDHLHGRRASTPFSRGPLIPESQ
MILPQLERLNEREWWTVGSQPAVDGIDSGDPVIGWGPRSGYVFQKGFVEFFCETKDVDEL
EKRLDIHGKGWVHLIASNYKGEIRTNIPEGARNAVTWGVFPGQEIVQSTIIEQASFLNWK
EEAFAIWSEWSSFYRPGSEERKLLENIRDTRWLVSIVHHDYKKADALWQFLFDGQ
>A0A3N1ZXN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteococcus japonicus|TrEMBL
MPQDAPTIADLLAIAQRPLFGFEFLPPREEAEYARTLSAVERLEPLKPDFVSVTYGAAGT
NRERTVETTRQIAATSTIPVIGHLTCSSQSRQQLEGVIDAYAEVGVRHVLAIRGDMPGGP
TVPWEKHPEGLANATELVRLVKGRGDFCVGVAAFPDVHPERRDADLDARILVDKYEAGAE
FAITQLFFNPDAYFDLVQRVRMLGCPIPIIPGLQPVTSLKQVKFFEELSGAPVPEQVKLR
LGEADGDPARVREIGSRIASEIAVTLLRGGAPGLQFFTQNRSLATREIFAMLLERRW
>A0A852RIT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides kongjuensis|TrEMBL
MRAQDRATVRRLLGNARYEILPTATIEAKVLEAVPTEVPLTVTASPSMGLERTVGTAERL
AAAGYTVVPHLAARMVSGRAELVELVDRLTAAGITNVFVPGGDADPVGDYHDAVSLLEDL
TAIGSPFAHVGVTGYPESHPKIHDDLTVQSMWDKRKHATYIVSNLTFDPAVIKDWLQRVR
RRGVELPLLLGVPGPVDRAKLLGMATKIGVGDSTRFLAKQKGLMTRLVAPGGFTGESFVE
KCAPTLGDPLMRVSGLHLYTFNQVAETERWRQDWLARLDG
>A0A831YB36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurihydrogenibium azorense|TrEMBL
MKIIDKLKQVKTSVSFEFFPPKTKELEESLFNTIEELKHINPTFVSVTYGAGGSTREKTR
DVVKKIHEETNLTVMAHLACVGHSKYEIKSILDDYQRIGIENILALRGDIPISFEKENLP
SDGCKNAAELVSFIRENYKDYYCIAVASYPEGHPESPNLERDIYYFKKKVEMGADFSITQ
MFFDNNFFYEFIEKCQKVGINIPIIPGIMPITNFNQIRKFASLCGATIPEDVIKIFEKYA
DNPEETKKVGIEFATKQCEDLLKNGVKGLHFYTLNKSDATIRIYQNIKNLIA
>A0A7V2NFN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotogaceae bacterium|TrEMBL
MDALNNIRDSISRGKSILVEVLPPRGPNIDKFMKYCLKLKEIGINGLSVTDMPVGRIRVS
PWGVSHLLLKEKIDVLMHYTRTNRSMIRHESDLLALSVLGIDNLLVLSGDDPKGGDYPFS
TKVEDISIDGLIRLIKFLNEGTDLANNNLNGKTDFFIGAALNPYSHDIEREIEKAKAKVD
AGVDFFVTQPIFDTDKFKRFLD
>A0A2C3MFN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6I2AEB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPVYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6N7EMU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Georgenia subflava|TrEMBL
MVPAVFPPTTVTQPTVSFELFPPRRPELDEVIWQRVLRMAAAGPDFFSVTYGASGTSRLA
SAELVRRLITEAGVRPIAHLTCVGATRDELAGMVRSLLDAGVRDFLALRGDPPVGEQVWR
PTAGGLDRASDLVALIREIQAEHLGRPCETGRSTTEPPSVVALDLGARAADSVSVSVATY
PSGAAHGRTAELAALREKQDAGADFAITQVFYDAEAYASLVADARDVGIELPILPGIIPM
TDARRLQRLAGLSGVEVPRSLQALLSVEDDAERLRRGIDATVALIDRVLAVGAPGIHLYT
FNQDRPALDVVEHLRDRGLRNPALSRAQPGCAAMPTGSAPLPRATPGATVLSPVAR
>A0A837TZV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum|TrEMBL
MHSPMFTLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIARTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPGLKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRAAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNAEPLFLGTQG
>A0A316XZH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIVSIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIQKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARVLKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>T0I262|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium lindaniclasticum LE124|TrEMBL
MTFAERPVSAPLFEDLPGDISVSFEFFPPKTEKMEEQLWDAITQLAPLDPSFVSVTYGAG
GSTRERTHSTVSRLVRETSLVPAAHLTCVGASKDEIAEIADQYWEAGVRHIVALRGDPPP
AQGGVFTPHPEGYSGAADLVAGLKARHDFDISVAAYPEIHPEAASADADLDNLKRKLDAG
ANRAITQFFFSTDAYFRFLDKALAAGIATPILPGIMPVTSFAAIRRMSGNTEIPGWLEKM
FEGLDERPGPRALVAAVAAADLCRRLYQGGVRDFHFYTLNRAEQAYAICQLLGLRPKAEA
>A0A1D3NNS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARVLKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8H7BSK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apophysomyces ossiformis|TrEMBL
MKIIDKIRRAQEENTLCYSFEYFPPKTEIGLANLFDRLARMASLEPTFVSCTWGAGGSTQ
ERTLEICSTTQNIYGLETLMHLTCTNMERDKVDQALKEAKNTGIQNILALRGDPPRGHEY
WTPCDGGFSHAVELVKYIRQEYGDYFCIGVAGYPEGHMDAATAEQDLQYLKEKVDAGADF
IVTQFFYDLDIFYKWVKDCRDIGITVPIVPGIMPIATHQSFRRMLNLSKVQVPKSILDTL
ESIRTSEANRKWGQPKVENDITELFVQYIMGHLNSLPWCEEALETETETIRNQLADINRR
GYWTISSQPAVNGAPSHDPVYGWGPKGGYVYQKAFIEFFVSKKQLDKLLKAFECDEYITY
YAANRKGEFLTNVSDTECQNAVTWGVFPGKEIVQPTIIERANFEAWKDEAYALWTDWEQQ
YTRESDSAKLLKDIGEQYWLVNVVHNDFQEPDSLFNVFLS
>A0A423S4B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp. NJUB218|TrEMBL
MKQALLDGQFFCVLEIIPRQSSSSTSAHKKILRRGHLAGWPLFLSFSDRVGLHCDLSPLE
GAAALGDPSSSLLHFSGKDRERIDLLLYLDAMKARGLSQLLLLSGDRLPCHHPEQSPVHY
LESVPALQIARTHCPDWLLGAALNPFKYLEEEGCAQYLKAQKKILAGADFLTLQLGFDAA
KHLEAQTWMSAQADTKPMLACVMQLTAKRATGLNHVPGIVITKSMRAVLDRELNVSLSYA
DTRSFERLGLQIVGLQLMGYAGVYVSGVHALDELIALEQVIGRYRDRISSVADWMGLWLE
SWEIPGAPKVCFTPESANWEIGQSDVKASHLEQLRYTLLSKVHHLFFSRYGWLSKAFGWN
VTRPFWKNSTAASALHALERAIKRPLVGCDTCGNCRLHDTFYVCPETCPKGLANGPCGGT
HLNRCEFGDRECIHSVKYRIAKSVNQLPLLSQPVTPCIDAIDRRQSSWPKWFKQDPDR
>D1AKA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sebaldella termitidis (strain ATCC 33386 / NCTC 11300)|TrEMBL
MKIKDIYQNKKAVFSFEIFPPNENFSSEKLYGVIDELSIQKPDFISVTYGAGGTTKGGTI
EMASYIKNKLNIEAVTHLTCVGSRKDEIENFLNELERNNIENILALRGDIPKDQDESIYD
RGDFLYASDLIKAVRATKRFSVGGAFYPEVHHENNDLIDLFNLKKKVDSGTDFLVSQIFF
DNESFLDFRDKAEKVGINVPLAAGIIPVTNAKQIKRITSLCNCKIPKKLERILNAYEDNN
EAMYQAGIAYATEQIIELLSAGIKGIHIYTMNKTNAVKEILENISSIRKYYE
>A0A1W1XR57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Andreprevotia lacus DSM 23236|TrEMBL
MSAPTFSFEFFPPKTPEGAEKLRITRQQLAQFKPQFFSVTFGAGGTTQEGTLNAVLDIRK
DGLAAAPHLSCIGSSRASIAEILQRYRDHGIRHIVALRGDIPSGMVDVGEFRYANELVAF
IREQHGDWFHIEVAAYPEYHPQSQNAEADLRNFVNKVNAGADSAITQYFFNADAYFHFVN
EVQARGVNIPIVPGIMPIQNFAQLARFSDICGAEIPRWLRLRLASFGDDTASIRAFGLDF
VTELSDRLLQNGAPGLHFYTLNAAGAVSTVWQRLGL
>A0A1C5HMC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora humi|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTPAGEKLLWQAIRELESLLPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRSVLAVR
GDPPGDPGGEWVTHPEGVRYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIARSVQLSGAPF
PPALAERFDRVADDPEAVHRLGVEQAGEMCAKLLDEGVPGIHFITLNRSTATREVWQRLR
ADARV
>A0A1J4YVD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilaceae bacterium CG1_02_62_390|TrEMBL
MAEHIFSMEFFPPKTAEGAAKLRETRRQLAQLKPRFFSVTFGAGGSTRERTLETVLEIQS
EGLGAAPHLSCIGSTEENIREILQTYKAHGIRHIVALRGDLPSGVADPGEFRYANELVAF
IRKETGDWFEIEVAAYPEMHPQARNYQQDLLNFKRKVEAGANAAITQYFFNADAYFQFRD
ECLALGIDIPVVPGIMPISNYGQLARFSAMCGAEIPRWLAKKLESYYDDSASIKAFGLDF
MTQLCDRLLTNEAPGLHFYTLNQAGLTSTLWQRLGLSR
>A0A5M6IHJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseospira marina|TrEMBL
MPYDSLGLRTSTDAASARAGACLPSFSLEVTPGAARKVPSFAALLPAGTAVYITSLPGTD
PAEVMALCRRLRGEGLRPVPHLAARSLRNRADLSDWLGRAVHEVGVRDILLLAGSADRPA
GPFQDTRSVLESGLLDAAGLSGFGVAGHPEGHPQANRGALWDALRMKQAFAEAHGLNAWI
VTQFTFSAKPVLAWLRTLPQEGIALPVRVGLPGPAKPATLITYARQCGVGASLRVLTRRP
DVLAGLVKAWAPDAIVDDLSKGHTRDAVWSVAGVHLFPFGGFAKTAAWGTTRWATGTGHT
VPSPPASDAAQSPAI
>Q5LP36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)|TrEMBL
MLRVRQEAKHRPLRRMTAQMTAPQISFEFFPPKNLEASFRLWDTVQVLAPLAPRFVSVTY
GAGGTTRELTRDAVATLHKSSGLNVAAHLTCVQASREETLAIADSFAQAGVTDIVALRGD
PPQGEGRFTPHPGGFANSVELIQALAETGKFAIRVGAYPDIHPEASNAQADIDWLKAKLD
AGADEALTQFFFEAETFFRFRDACAKAGIDKQITPGILPIENWKGARNFARRCGTHIPAW
VEDAFDKATRDGREDLLATAICTELCSELIEGDVDKLHFYTLNRPELTRDVCHALGVTPK
VALQNVA
>A0A1L9X1Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus aculeatus (strain ATCC 16872 / CBS 172.66 / WB 5094)|TrEMBL
MHIKEKLSQNEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPVEKVDAALQAAYKAGCTNILALRGDPPREKEN
WEATDGGFRYAKDLVKHIREKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDNFIDWVKKCRNKGVAVPIIPGIMPIQTYAAFIRRSEWTKTRIPPEWLEAL
EPVKNDDAAVRNIGKRLVADMCRRLLQSGLNHLHFYTMNLAQSTQLVLEDLNLLPSEETP
LQRALPWRPSLGLNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGQPKSIRDITHIFVDFLEGKLARLPWSDSPITAEANAIKDDLIE
LNKKGIFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLIPSYLLDDLIARIEKNG
YLTYHAVSKNGNLRTNTNDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQSVVDDWSLVNIVNNDFHNTSSLFDLFKDLTVKDLDTEIAVEDGETK
VHQNGVANGVEATNGTVANGTTTELPVKN
>A0A2N2XMB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-23|TrEMBL
ELVTQIHNLNKGIYLDEDLQNSSCTNFCIGVAGYPEKHMEAPSVDSDIHFLKQKIKNGAD
YIITQMFFDNKRFFDFVAKCRAAGITVPIIPGLKPIATKKQLNLIPHRFKVDLPDDLIMA
VVKAKDNDAVKQIGIEWCTAQSKELVAAGIPVLHYYSMGKAENIKAIAKEIF
>A0A353BQF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Subdoligranulum sp|TrEMBL
MTITEQFKAKRCVFSIECFPPKQTTQMDKLKDTLRQMQAMDPGFISVTFGAGGSAGGVST
AEVADYIQNELHVPTLAHLICMGNDETRAAEILDQLESVGVRDVLALRGDRTPSRPDSPD
FKHASDLTSFIKWKKPEFSVHGACYPEGHPEADSLLHDVENLRIKQAAGAEHLLTQLFFD
NMHFYRFLNLARRAGITLPVSAGVMPIVKRSQIERTVSLSSASLPSEFTRMISRYQDDPA
SLYDAGIDYAVRQLRDLIEGGADGIHLYAMNDAAVAAKVYDGIRDLL
>A0A6B0TQN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanomicrobium pacificus|TrEMBL
MHTETVSKQAPGLSFEFFPPNTPEGAARLWRSVERLAPLAPDFVSVTYGAGGTTRDRTNK
AIRTIRERAGLPVAGHLTCVGASRDETLDVARSYAALGVRRIVALRGDPPKGADGFTPHA
DGFASAAELVSGLRAAGDFRISVAAYPEKHPEADSLAADIDNLKRKLDAGGDEAITQFFF
EADTFLRFRDACAKAGIDAPIIPGILPVENFTKMVNFAGRCAAHVPDWMHDAFRNADGQE
AQDVLATAVAAELCDTLLTEGAGHLHFYTLNKPDLTYNVCRAIGIATAAPGLAEGAGAA
>A0A4R3MQY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natranaerovirga pectinivora|TrEMBL
MNFKDYIKDHILITDGAMGTYYSQLINSNHTLSEKANLNNPEVVAKIHKEYIAAGANLIR
TNTFSANTKVLNEGIDKVKEIIIEGFNIAKKTVQESNNDVIIAASIGPVPENDFTSDEEV
INEYKIIVDTFLQEGADTFLFETFSDIHYLKDIIPYIKSKNPETTVIAQFALNIYGYTKI
GKSANRLLDDLRSINGLDIYGFNCGIGAGHLYQIIKKLHWNEEEIISAMPNSGYPDILQD
RTVYMDNTDYFVDTMINIAKLGVKMIGGCCGTTPIHIEKLAKAMESFDVNDVKKPTNKKK
VVQTQERNINPFEAKLMNNKEVIAVELDPPFGKDIEKVMESANLLKANGVDIITIADSPM
GKPRADALIIASKIAREVKIPTMPHICCRDKNIIGLKAQILGGYMENIRDMLLVTGDPIP
SGDRNEIKSVFNLNSITLMEMVREMNIEHFKDEPIHYGGALNPNRANLDKEIERMKKKID
AGATFFLTQPIYDEKTLEKITYIKSKLDTKILGGILPLVNIRNARFIQNEIIGITVPDEI
INQFDENMTREESEQIGIEIGKNIALKMRGIVDGYYFMVPFNRVNMINEIINALKKGENK
>A0A800KPX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIKDILATTRPVSFEFFPPRAADGIPAVLETLDELKVFCPDYVSVTYGAGGSTRAFTEE
ITFEAKRKAGVEVMAHLTCVGQTKEEIHGVLERLNAEGVENIIALRGDPPRGAMEFVPVE
GGFQHATDLLEHVKANFDFGVAAACYPEGHTESVDLVTDMKFVKQKVDNGADFLITQLFY
DNRHYFDFVERARAAGIEVPIIPGVLPVLNSGQVRRFTALSGSEIPPELDKLLDKYADNE
SGARDMGVEYASAQVRELWDAGVPGVHFYVLNRSYSVSRILDNLTIPGHHRLD
>A0A4Y6PZE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Persicimonas caeni|TrEMBL
MGKATKVTREFLEVVDAGPVVFDGAVGTQLYERGIYINKSFDDANLSQQDLVRSVHEAYL
QAGADVITTNTFGSNRIKLKRHGLEDRVVEINRQGVLLAREVAQDAAFVAGSVGPTGLTP
TMLTDAELDEIRQAYHEQITALADAGADLIVLETFRQLSEIRIAIEVAKDVCDLPIVAQM
AFDSDMKTGDGAAPDRVALLLKQWGADVIGANCMEGPNVLFDVVEQMIGHGLPVIAEPNA
GYPRKVEERLVYMATPEYFGVYARRFFKLGVNIVGGCCGTGPEHVRQIAAAARMMGGGRI
KVEMAEADKVEQRVEEGLDAIPLEDRTNLARKILRVQRERVLAPPDKRPPVSRDTFVVSV
EVNPPSGLNPDKSIESAQMLIDGGVDVINTSDGPRASVRMDNGAFAALMRKRVGCEVIVH
YCSRDRNLLGLQSDLLGLHVLGLHNLCVITGDPPKVGDYPHATAVFDLDSIGMLRMISNF
NRGLDPSGKSVGDVTRFFCACGAEPAAKDYEREIRRLEEKKAAGANFVMTQPVYDHRVLE
RFLSDIEHLELPVLVGLLPLASHRNAEFLHNEVPGMAVPDDIRKRMKEAGSGPQARAEGV
KIAQETLEMVKDQVVGAYIMPPFGRYVAALEILQCIDGYPEVG
>A0A7C4AMX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MPTISFQHALTNPEVFCVSWELVPGRGARELQQEEILKMATAAAASGKIHALSITDNPSG
NPGLSAEFLCTELARCGIEPVVHFACRDKNRNAIESLLYGLERSGVHNLLVVSGDFPSPA
GFCGTARPVFDLDPVQVMQLIAQMNSGYAYREYGREARLVPTHFFAGVAVSPFKKTEPEL
SGQYAKLQIKIAAGAQFAVTQIGFDPRKFHELILWLKQHEIHIPVLANLFVLSYPSAKFI
AAGNIPGCVVPPKLLEELSRDHEQPDKGRSARIRRAARFYAIAKGLGYAGVHIGGHKITH
QAVLEIIQQGEELFPSWQDILSACDYACGNLFYYYFEPAPPPVLNSNNSNLQANRAPFRL
RLRSFGYRLCLLMHRIFFAPSSPLYPVLRLCAQHLDRSVFARRLVSRLEHIIKTIIFRCC
DCGDCSLPDTAYLCPLSGCPKSQRNGPCGGSDNGWCEVYPGEKKCLWVRVYERRSATSTE
PDISTTIVPPCNWQLWQTSSWLNYFLGRAHTSPVPCRRQTQQKNAAS
>A0A806VDZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cepacia ATCC 25416|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLMPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLVDAGVPGLHFYTLNTAAATRTICERLDV
>A0A7V2VRV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAQSFKEAINSGKFVVTSEISPPKGSNIEKMCHHIDTLKDKVDAINVTDHQSSVMRFPSI
GGCLYIKERGGEPILQMTCRDRNQLALQSDLLLAYVRDIRNVLCLTGDAVVVGDHKEAAD
VFELDSTQLLRAIRQLESGKDLGGNDLDGAVEFYAGAIVTPEAQPIEPQLIKFEKKVEAG
AEFFQTQAIYDLDNFSKFMEYARQFPVKVLAGIVLLGSARMAKYMTENVPGIFVPKDLID
ELSGAPKGEALNKGIEIAGRMIAALKRDSICDGVHIMAIGREEVVPDILAVAGLSTEIEK
K
>A0A7C3BTJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MGLQESLEAGKFVVTVEIGTVVGTDITEIKENGEALLGRIDGGNVTDQQSAVLHLGSLVT
CHLLKQMGHEPIFQVTCRDRNRLALQSDLLSAYVLGIRNILCLTGDYFNLGDHPEAKPVF
DLDSVQLLQAIGRLNEGYALSGTELNAKTDLFGGAVVNPGADTKAAFELQIIKMEQKIEA
GAKFFQTQAIYEPDVFAKFMDRAKQFNVPILAGIIPLKSAGMAKYMNKNVSGVFVPEDLI
NKMKEAEDKVQTSVEIAADIMKGLKDMCQGVHLMPIGWEKHVPAMLDAAGF
>A0A2G6J1L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTTANGDSTRGSFRDFLAGDGVALFDGAMGTMLYQRGVFINRPFEELNVTRPEVVREVHE
EYIAAGADILETNTFTANRFRLSPHGLADKVGEINAAGAAVAREAAAASGAWVAGAVGPL
GVRIEPFGPIGRDEVSEVFAEQAKALHDAGVDLFILETFGHLPELVLAVKAVRSASDRPI
VAQVAVGTGGMTREGVKSRDAARQLTEAGADVAGVNCSDALGTLAALAGMRAGTDLPLSC
QPNAGQPKSVEGRKIYLGSPEYFDAWGRRALRQGARLLGGCCGTTPEHIRALRAILGEEA
PSAQAAAVARPASLAPCAEPVPREKKSMLAAAMAADRFVVGVEVPPVRGWEIDDVTARAR
ILALAGVDFMSIPEGASSIAHLPPIAQAHACRRLGMATIIHYSTRGRRLLRMQSDLLGAA
ASGVANLLCITGAPLTSGAEQDAWPDLEVDSIGLVNLVNRLNHGEDVGGNPIGRPTELFC
GVHLDPSAYDRERERSRFFWKVDAGAEFAITSPVFDVGALLACLERLPTVGEGPVPIIAT
IWPLTSASQAELLEHEQSMVPAPKQIVTRMREAEGAGTEEAEGLLIARELAAAIKPHVQG
IQVIAPRGDVELALQVLDAAR
>A0A2K2VP25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp|TrEMBL
MFNELINKLKNDTYITLETTPGHSPIFSPIIETIAELGLDKLVDGFTTTDNPLAKLKYNS
LFAAKMLQERFNKPVIATMSMRDRNKIALQSDLLGANEVDVRAVLALTGDPASISDQPHT
KGVFEADSTLLLEIISCFNSGIDYAGKPLTHKPKEIFPFAVVNSYAKNPKTLQKKMQKKI
KNGALGIITQPVYDLQSAKLLLELKEAANEECCNENKSAEIILGIFPITKLRTAQFLSAH
VAGINVPNAWIEALREAHEKGADEEHKVGFELSKNLFLELKTLHPKLHLMTANQFGLAKN
ILS
>A0A445L602|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycine soja|TrEMBL
MKIIEKIRAASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVQHIRAKYGDYFGITIAGYPEAHPDVIESDGLATPEGYRNDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKVSRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALSDYQFMRPRARDKKLVEEWAVPLKSVEDIYERFRLYCLGKLRSNPWSELDGLQP
ETKIINEQLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKL
DALVDKCKDRTSLTYMAVNKDGSWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFNVW
KDEAFEIWSRGWASLYPEDEASRKLVEEVGF
>A0A2T3ZLS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma asperellum CBS 433.97|TrEMBL
MHIKSLVADTEKTKAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLDKVNDALQKAYKAGCTNILALRGDPPRDQTT
WTAADGNFRYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGAGF
IVTQMFYDADNFLRWVGKVRERGITVPILPGIMPIATYASFLRRAKHMQCRVPPEWMTLL
EPVKNDDVAVREIGKTLVADLCRKLLAGGIHHLHFYTMNLAQATRMVLDELDWTPSAERP
LKQALPWKQSKGFGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTCVQDIADTFVQYLEKKIETLPWSESALAAEADPIKDDLVA
LNKRGILTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLIPPYLLDEMISRLDDFP
NLTYYAVTKNGELKSNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFDANTPSRALIEGIMNEWYLVNIVNNDFRENNTIFGFLEGLQVKDAAVPVNGTA
>A0A353MWY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp|TrEMBL
MKIKDILSQGKPTLSFEVFPPKTEDKYEXTSQYTVDIASALHHQHHVTALAHLTCVSSTK
EKVHQVLGELKEAGIENVLALRGDMPTNAPAKKEYHYASELIREIKEAGDFCIGAACYPE
GHVESANKTIDMDYLKQKVEAGCDFVTTQMFFDNNILYNYLYRIREKGITVPVVAGIMPV
TNVKQIIRSCQVSGTYLPSRFKAIVDRFGDNPAAMKQAGIAYATEQIIDLIANGVNAIHV
YSMNKPDVALKIKENLSEIL
>F9GSG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus haemolyticus M21127|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWKSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIESYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPE
>A0A2G2CNG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp|TrEMBL
MFDTLIEKLNNGTYITLETTPGHSPLFAPTIEKIAELELDKYVDGFSTTDNPLAKLKYNA
LFAAKMLQDRFNKPVIATMXMRDRNKIALQSDLLGSNEVDIRAILALTGDPATMSDQPRT
KGVFEGDSTLLLDIISAFNAGMDYAGKPLAHQPKHISAFAVVNAYAKNPKTLQKKMQKKI
KHGAIGIITQPVYDLESAKLLLELRDNANAECCPDKKKAELIFGVFPITKLRTAQFLSAH
VPGINVPDLWLEKLRMAHEKGPEEEYKVGFELSKTLFDDLKALHPKIHLMTANQFSVARD
ILC
>A0A2G6CPF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MPMLSDDFVITIEVVPPGGPDPSPLIDTLASLSALPFSGFSVASNPVAKPRMSAMALCAM
IRKHLDKPAVLHLTTRDHNRLSLQGELWGARALGIDTVMLATGDLVAFDDRHATTTVRDT
DIYGLVRMARESGMQTGVVFDIHPERNGLSQAVAHLKRKVDAGAQFAVTQPVYDMAGADQ
IADATHDMRIPMIMGILPLRTPRHADFLHHKVAGIAVPESLRARMHMAEDPVKEGVANAR
EMVSAARQSFAGACIMPPFDHFEVMTDILFPDPGSISFNLKRTHRPPSTNNTPGKRTNDQ
SNNKGRHP
>A0A352UCQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MLRDRASLNPFRLRRPTVVSATSVSRWHAGVVKILSTWRQAGFYPIPVATTRDMLIFLYL
RRRSASKFMRHLMKISDILKNKRTLSFEFFPPRDEQGVERLFETIDHLKRYEPDFIDITY
GAGGSTQRLTVELCVRAYRDSGVTVMGHLTCSAQTKEMVHSVLKRFESEGIENVILLRGD
PPQGEDTFVPAEDGFSHATDLVQHTKENFDFGIAAACYPEAHPESLDADSDLYYTKMKVE
QGAEFLITQLFYDNEDYYAFVDRARQSGIDVPIIPGLMPILNASQIRRITSLCGATIPAG
LDRQLERHADDNRAVRQIGIDHTLRQAQELMGSDVPGIHFYVLNRRYSITKILDNLQGSS
VGVTSS
>A0A4U1L558|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. L-1-4w-11|TrEMBL
MTIPAIHPNWGRAPEGMTDGYSLEMTAKDRPALAEAAARIAPETPVAITFLPGESMDARI
EAAADVRRLGFEPMPHLSARRITSHDELEQTIRRTVAEAGARRAFLVAGDPPVPAGPFAD
TMALIQTGLFEANGIQAIGIAGHPEGHPAMDEAQCWEALETKQAEIARRGMATLIVTQFG
FDADAFIDWLEKLRARGIDAPVRIGVPGPAGIKTLMRFAAHCGVGASTAVLSKYGISITK
LLGTAGPDKLVDRFAERLGPQHGPVRLHFYPFGGLVRTVEWINDYEARHK
>A0A3D1YH92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIRNILKSKQTISFEFFPPKLASGLENVIDKMNVLSKYNPDFISITYGAGGSTQSFTEE
LSRIAKRDLFLEVMSHITCVGQTANEIDNMLNNLLTSNIKNIIALRGDPPKGETNFTQTP
GGFKYASELINHINQNFDFGIAAAGYPETHIESFNIEQDIEHLKSKVSTGVDFLITQLFF
DNNHYYNFVDRARNAGIEVPIIPGILPILSVPQIRRITQLCGASIPMELNKQLEFIKDDN
DAAIQLGIEHATKQVQDLLKQGAPGIHFYVLNKNYSIEKILTNLNLVPSE
>A0A5M8SVR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium AB60|TrEMBL
MASFSDIFGDRPVLADGAMGTVLYARGIFINRCYDELNLSDPSLILAIHEEYLQAGAEIL
ETNTFGANRFRLARHGLAGKVAEINAAGVRIARDAVRHLKDKQAGEAWVAGAIGPLGVRL
EPLGKTGLDEARAAFAEQIAALRDAGVDLLIVETMPALNEAREALLAAHDTAPHLPVLTM
VTVDDESNCLDGSSPAHAAAVLSEWGANAVGVNCSSGPATVLTAIETMRAATSLPIAAMP
NAGLPRAIEGRNIYLCSPEYMASFARKAINAGAQIVGGCCGTTPNHIRAMRSAMRAIDAQ
ARVVEGETVVPLETETPPAPLRERSRIGALIAEKQFVTLVEIVPPRGIDCHKEIEGARLL
ASLGVHGINVPDSPRASARMSGQSLCVQIQQHTSIDTVLHYTCRDRNILSIQSDLLGASS
IGLRNILCLTGDPPKLGNYPDATAVFDVDSIGLVNMVRRLNHGLDIGSNSIGSSTNFTIG
IAANPGVPDIEHELRRFKYKVEAGAEYAITQPVFDLRLLESFLERIAEYRIPIIAGIWPL
TSLRNAEFMKNDLRVSMPEEIMLRMAQADSPEAASREGIAIAREMLEAVRPYVQGVQVSA
PFGRYTAAAEVIASVLPQPQSQPASTGVS
>A0A7K3WWQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. PPF5-17B|TrEMBL
MALGLPSVLPNPQPAIGELIRDGQPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGNPGGEWVRHPEGVRYAEELVRLIRDAGDFSVGVAAFPYKHPRSPDVTSDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFERVADDPEAVRRLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWQQLR
AGARV
>A0A7W6G1A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium skierniewicense|TrEMBL
MTKTEADRHVTENFKLSFEFFPPKNADMDVQLWETVEELSRWNPDFVSVTYGAGGTTKAP
TLVAVDRMISVAGLPTASHLTCVDASKQEVHDVVEELRAIGVKRFVALRGDPATGPGTAY
KPHPDGYENAAALVRGLRELGDFEISVSAYPEKHPESESDSVDIDMLKRKADNGATRALT
QFFFDNDIFERYMERVTKAGISIPVVPGIMPIQNLTQLKRFAGRCGTSVPAFLDDRFAGY
DDDAIGRARVAADVAAEQILDLQRRGLNEFHLYTMNRAPLVNAVLENVGYRPMRKSAA
>A0A6S6XM54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcaceae bacterium BL-6|TrEMBL
MYISHLYQKNATVLSFEVFPPKKDSDIESIDGVLKDFADLHPDFMSVTYGAGGSAQTVSR
SKKLADKIENTFHIPALFHLTCIGADKKRLRELLLQLRQMKIQNILALRGDFPGDGSGTG
DYTHACDLIRQIKEEGGFCVGAACYPEGHIDCESPELDREYLKRKQEAGADFFISQLFFE
NRYFFRFLNDARKSGITVPISAGIMPILGRKQIERMIFMCGASLPGSIVKLLHRYGDNPA
DLRKAGIEYALRQAEDLIANGADGVHLYTMNHPDIARSAMWRFRREKTANHE
>A0A1C3K8V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tremblaya princeps|TrEMBL
MVNVAGSSPVRCALRVMPGLSFEFFAPRSHAGSIRLMCAQQVLSRFVPRFVSVTRSASIG
QQAHIETIASTLRVFPRTAPHVLFCQCPRALARELRAYELLGIRHLVLLRGDNGTAPGEL
GAPELVSLVRRSYGEAFYIDVAAYPDGHPMASTVFDDVRALARKVRCGANSAITQCFYNP
DAYYRLQDELQRLGVSLPVTPGIMPVLSHAYMSRFILPSGVDVPAWILKRLEALRYCSAS
VLEFGTDVALSLCESLAARGASDFHLYTMNDHRAVWRVCEHVLGTAATCHRSGA
>A0A3A1XIQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium WP021|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIANTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQESAGVFEHASDL
VYYIRSKHPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNADCLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A7K5B1B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Furnarius figulus|TrEMBL
MVNETQQSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYETDLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A160F4H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus amylolyticus|TrEMBL
MGLLEDVKERIVLADGAMGTLLYSHGIDRCFEELNISKPEEIVHIHEAYMAAGAEVIQTN
TYGANYVKLSRYGLQDDVQTINRAAVLLAKQAAKGRAYVLGTIGGLRSVNKSAITLEEVK
RTFREQLYVLLHEDVDGLLLETYYDLEELKTVLAIARKETNKPIIAHVTLHDVGILQDGT
PLNEALAQLEQLGADIVGLNCHLGPYHMIRSLEEVPLPATAFLSAYPNASLPDYRDGRLV
YETNAEYFKETALAFRDQGVRLIGGCCGTTPSHIEAMAKALTDRTPVQQKQVKQRALSVS
VSAPPEQTEPPLTEIVRKRRSIIVELDPPKKLGITKFLEGAKALRDANIDALTLADNSLA
TPRISNVALGTIVKQQLGVRPLVHITCRDRNLIGLQSHLMGLYTLGITDVLAVTGDPSKI
GDFPGATSVYDLSSFDLIQLIRQFNEGVSYSGQPLGQKTKFSIAAAFNPNVRHLDKAVQR
LEKKIQCGAHYFMTQPIYSEKQMEAVYDATKHLDVPIYIGIMPLTSARNAEFLHHEVPGI
TLSDDIRARMAACANDPIQSTKEGIAIAKSLIDAAFDLFNGIYLITPFLRYEMTVELAQY
VHEKQAAKERKVLHG
>A0A286DJC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces zhaozhouensis|TrEMBL
MSGRAATVRDLLAAGERSFSFEFSPPKTEQGEKTLWNAIRRVEAVAPTFVSVTYGAGGSS
RERTVRATERIATETTLTPVAHLTAVQHSVAELRNIVGQYADAGIRNMLALRGDPPGDPM
AEWVRHPEGVSYAAELVRLIKESGDFCVGVAAFPEMHPRSLDWETDIRYFVEKCRAGADF
AITQMFFRAEDYLRLRDRVAAAGCATPIIPEIMPITNARQIDRFQELSNTSVPPDLKRRI
LAVKDDPMAVRSVGIEFATELCARLMDEDIPGLHFITLNTSSHSTATLDVYKNLGLHQRS
>A0A2N0BC45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira ellisii|TrEMBL
MKRISEIYGSTKGPVYSFEFFPPKTPEGDVKLMETVKELSSLHPDFVTVTYGAGGSTKDK
TVEISSLIGKNHSIPAVPHFTCVGADQAQILESLKRIRSEGILNLMALRGDPPKGQGEFK
KTPGGFENATELISFIRLENLDFCIGGGCYPEKDPLRPQIPXXXTLEEDVRHLKLKVEAG
ADFLVSQLFFMNSAFEKFLNLVRKIGIGVPVIPGIMPITSFSQIERFRSIAGCEFPSSLI
RDLQEVEHRPEEFYRRSLNFTVKQCRELLDMGVPGIHLYTLNQSHASYDIVRELKDDSV
>A0A2D8J5T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium|TrEMBL
MQSQKQFERRFSFEFFPPKTDAGVEKLQQTRDELAERKPSFFSVTFGAGGSTRDRTIETV
LKLHKQGISTAPHLSCVGSTRESVAELLDIYRDNGVNRIVTLRGDLPSGMGSAGELRYAN
ELVAFIREHSGDHFALEVAAYPEYHPQARSAEEDLKNFQRKVEAGANSAITQYFYNPDAY
FYFIDRLEKAGVTIPVVPGIMPIVNYSSLIRFSEMCGAEVPRWIRKQLDAYGDDSESIRK
FGEEVVTEMCRKLLAGGAPGLHFYTLNQSAPSLAIWDNLALAPEPKISF
>A0A385B3I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. phDV1|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFG
EQVITEMCERLLQDGAPGLHFYSMNLAGPSLAIWNNLKLSR
>A0A1C6VPW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora peucetia|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTEQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGDPGGDWVRHPEGVLYAEDLVRLVRDAGDFSVGVAAFPYKHPRSSDVAGDTAHFVR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCATPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFAKVADDAEAVRRLGVEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLQ
AGARV
>A0A2W7AYK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp|TrEMBL
MFLASAPLGYRLRTAAKAGEFLVTAEVMPPKGGNPEHMLAMGQLLKGRVHAVNITDGSRA
VMRMSSWAAALLLQQQGIEAVCQVACRDRNRIALQADLMGVHALGVRNILALTGDPVKAG
DHPEARAVFDLESVRLLKLLGQLNGGVDSHDKPLADGALDLFAGAAIDPQSPSWSGLQRR
FEAKVKAGAQFFQSQLITDFDRLAKFMDQVAADYSRPVLAGIFLLKSAKNANFINRNVPG
AHIPQAIVDRLTAAADPLQEGVQIAAEQVQAARQLCQGVHLMAVRREDLIPQILDQGGVA
PVDALAQQ
>A0A8D4CJ77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citromicrobium sp. JL477|TrEMBL
MTAGPGTMFDPAREADYATTPPLFSGLPGDIDVSFEFFPPKTEKMEASLWSAIEELKPLD
PHFVSVTYGAGGSTRERTHKTVARIIAEAGLPAAAHLTCVNASKKETQRIAEHYWEAGVR
HIVALRGDMPREDGTLGPFEPHPDGYANAEELVRGLKEVADFEISVSAYPECHPDAQSPQ
AEIDYLKRKIDAGADRAITQFFFSPETFFAFLEKTDKAGIDVPIVPGILPITNVAKAREF
AGQCGAEIPQWMDNLFEGLDQRPAARQLVSATIAAEMCRRLYAGGIRHYHFYTLNRADLA
YAICHLLGMRPTENPA
>A0A8H9L279|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Promicromonospora citrea|TrEMBL
MVAEVHPHRPTISFELMPPRRPEVAPRFWETAEQLVAAGPDFVSVTYGAGGGDRATSRDV
LARLLRGTPVLPVAHLTCVGASREDVSEVIDEFLEAGVRSFLALRGDPPRDEPDWAPPED
GVRSSVDLVRLLRQVDERRCAADASAALRSAAHPLAVAVATFPDGNPGAGTTREQEVHRL
LEKQEAGASFAITQFFYRADSYTGFVDAARAAGVTIPILAGILPTTEARRLRRVEELTGV
AAPSGLLRDLDRLTGPDGSVDAEAQHAHGVEYSAALAREVLDAGAPGLHVYTFNKHRPAL
DLLARTGLTGRAAA
>A0A6N7KM81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces kaniharaensis|TrEMBL
MALGIASTRSDRALTVRELLAAGKRSFSFEFMPPRSEVGEQKLWDAIRRLEPLDPNFVCM
TYGAGGSSRERTVNMVGRIATETTLTPVAHLTAVDHSIAELRNIIGQYADQGVRNVLAVR
GDPPGDPMADWIKHPDGVTYAYELVELIKGIGDFCVGVAASPNMHPRSTNWDDDIRHFVG
KIRAGADYAITQMFFEVDDYLRLRDRVTAAGCEAPIIPEIMPVTNAKQLERFPQLSGSAF
PADLEARLRAAIDDPAALRAVGMEHATAMAERLLAEGAPGLHFITLNHSTATLEIYQNLG
LHRR
>A0A4R0JVB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella capetownensis|TrEMBL
MANGLASTRPGNRPTIRELLASGGRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWVAHPEGLNHAIELVELIRSLGDFCVGVAAFPDKHPEATSLEADAQVLAA
KAQAGADYAITQMFFGADDYFRLVDRAAALGCDIPVLPGIMPVTNIKQIQRMAELTGMAL
PTAVTDRLLAVEDDPAAVRQVGVEIATELCEQLLTGGAPGIHFITLNRSTATRQVFLNLR
SSVVS
>A0A7K1H2W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. CP22|TrEMBL
MALGLPSVLPNSQPAIGELVRDCQPTFSFEFMPPKTEQGERQLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGAGVRNVLVVR
GDPPGDPTGEWIPHPEGVHYAEDLVRLVRDSGDFSVGVAAFPYRHPRSPDVAADTEYFVR
KCRAGADFAITQMFFDADEYLRLRDRVAAAGCDTPILAGVMPVTRIGTIERSVQLSGAPF
PPALAERFERVADDPEAVRRLGIEQTSEMCRRLLDEGVPGIHFITFNRSTATREIWQNLR
VSVAT
>A0A6I9M3Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peromyscus maniculatus bairdii|TrEMBL
MHHRGAKVLPAEHCYPSLGTWASEAGCGRLSVPRSIRNPAMVNEGSSSGSEGSKDSSRCS
TPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDV
TWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCQQRQEEITGHLHRARQLGLKNI
MALRGDPVGDHWETEEGGFSCATDLVKHIRNEFGDYFDICVAGYPKGHPEAESFEDDLKH
LKEKVSAGADFIITQLFFEASTFFHFVKACTEIGISCPILPGIFPIQAYSSLRQLVKLSK
LEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEVL
KQLGMWTEDPRRPLPWAVSAHPKRREEYVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSS
SPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNQHGHTVTCL
PWNDDPLAAETSLMKEELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYL
EFFTSPETVEALLQVLKKYELRVNYHIVDVQGKNITNAPELQPNAVTWGIFPGREIIQPT
VVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDSCLW
QVVEDTFELLNRHTAKREAQAP
>A0A0N9NC23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia phthalatica|TrEMBL
MTDSTHPSSDVLARAGQSVVERLADPYPGPIPFSVEFFPPRDAEAEARLWRTARTFERMN
PAFVSMTYGAGGTTRDRTVRIAGELATETTLLTVAHLTAVNHSIDEIRGLVGAYADKGIT
NLLALRGDPPGDPLGEWVKHRKGVEYAEELVRLIDDLGDFHTGVASFPEGHHRSPNLAAD
TGNLVRKLRAGAEFSVTQVFFDVEDYLRLRDRLVAADPEQGAKPLIPGLMPITSLATARR
MTQLSGSKIPPQVEERLAKAAGDGPEENRADVRAVGIDLCTEMSERLIAEGVPCLHFCSL
NFVKATSEVLDRIGIDTRGALAAL
>A0A522WSP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacter sp|TrEMBL
MQSQKNHSQLFSFEFYPPKTDEGAASLQVVHSKLAKLNPDFFSVTFGAGGSTRDKTFTTV
IDIQAKGIPAAPHLSCVASTKDNIRGILKDYQDHGITKIVALRGDLPSGMMSAGEFRYAN
ELVEFIRQETGDHFQIHVAAYPEVHPQAVSAVEDFKNFKRKVAAGADAVITQYFYNAEAY
FHFVDSCEKNGITIPIVPGIMPITQYTQLFRFSEMCGADIPRWLRKRLESFGDDREAVQA
FGLDVVSNLCQRLLDGGAPGLHFYTMNQAAPTLAILDNLKR
>A0A1H8EF24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas gellani|TrEMBL
MTISVSQLEEARVALDGPLYADIAGDMQVSFEFFPPKTEKMEEQLWSSIRSLEPLGPRFV
SVTYGAGGSTRERTHATVARIQRETGLAAAAHLTCVEATREEIDAVAQEYWAAGVRHIVA
LRGDAPAQGARYAAHPGGYDNAAALVAGLKRLHPFEVSVAAYPECHPDSADATADLDNLR
RKIDAGANRAITQFFFEPETFFRYRDAVAAAGIQAEIVPGIMPVTNFASVTRMAAMCGTA
VPSWMARLFEGLDDHPGARQLIAATLAAELCRKLYAGDVRSFHFYTLNRAELAYAICHLL
GVRAQAQAQEVAA
>A0A430SHE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus|TrEMBL
MKIRDLLKARKGPLFSFEFFPPKTPEGEEALFRTMEELKVFRPAFVSITYGAMGSTRDRS
VLWAKRILDLGLNALAHLTVAGQSQEEVAGVLDRFVEAGVENILALRGDPPQGERVFRPH
PQGFRYAMELVAFIRSRYGEGVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFHNAHYFGFLERARRVGITIPILPGIMPITSYPQLRRFTEVCGASIPGPLLSKLERHQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNRSPATRRVLERLGFKPT
>W7SC04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kutzneria sp. 744|TrEMBL
MTSRPFQVVCEIEPPTRPDLMHVRHQIGTLSKVAGSFLIPDNHIGRATVSSVAVAHEVQA
MGGRSIACLNSRDRNMLGFRRDLLTAAAYGVEEFLFVYGDKPATGSRTGQLTVRTMIDEV
RSLSEDKAFSGVAPFRVGTAAGLRPLPSWKRAADFMFVQVSFSLDALLRWRDANPVDMPV
YAGVMVIASQAHAQRLASAIPDIDIPADLVDRLGSDRLAGVESTCEQVMRIRETGAFDGV
HLVPVARYREVAARLEQLLK
>A0A178AQD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stagonospora sp. SRC1lsM3a|TrEMBL
MERITDKINALPDGANYFSLEFFPPKTAMGFANLTTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRALIDEALEQAKVLGIRNILALRGDAPRSEE
YRDEGQTPEQDSNKDFTWAVDLVRYIRKEYGDYFCIGVAAYPEGHSDESHPEHQDPKNDL
PSLVEKTQAGADFLMTQLFFDVEAYDKFETMLREHESGAFKTIPIIPGLMPIQSYKILLR
TTKLSHANLPSNMLARLDAVKSDDELVKQVGVKILDEMVEHIKARPDPGRRGFHFYTLNL
EKAVSHILEDCDLIPRENLEDEDSVIVETTPAINLEPPTNGMSVKPRSRLSSMNSGTRNR
VIISHPSASKSNHSWEATEEEAGLPRGAINTRANTLAISEGEGSLGREATWDDFPNGRWG
DARSPAFGEIDGYGPTLHVSTPQALKLWGHPVDTGDISTLFRRHIEGELDALPWSEQGLS
PETSTIAKQLLALNAKGWWTVASQPSVNGVRSTDPVFGWGPKNGYVFQKPFVEFFIPSAQ
FHKLKERLDAHDQVTYFAGNAQGDFEASNEESVNPVTWGTFAGKEIVTPTIIEAVSFRSW
LEEAFSIWREWQRIYPSKSATCKMLGSTRQDVWLVNVIWGDFVQGNGLWEFLGA
>A0A1G5DTJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio hungatei|TrEMBL
MKIIDILNNKDVTLSFEVFPPKTDDKYADVEKAAAEIAALKPDFMSVTYGAGGGTSKNTV
NISADLQDKYGVTVLSHLTCVSSTKEDVKSMISVYKEKGIENIMALRGDIPKEGRICYDY
DHATQLISDIKSLDENICIGGACYPEGHVECARQSEDIIHLKEKVDAGCDFLTTQMFFDN
STLYQFLYRIREKGIEVPVLPGIMPITNARQVARSVSLSGSTIPQKMKIMVDRFADDPEK
MKEAGIIYACDQIIDLISNGVSHIHVYSMNKPDIAAGIMRNLSTIIK
>A0A519TGD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp|TrEMBL
MKVTEHLSRAAGKTLFSFEVLPPRKGENIHTLYANIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRKRPGTVGICAAIKNRFDVDTVPHLICGGFAKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFQPHPDGHRYACDLIGQVSELNHGRYHDHDEQYQPVGAEPVLCTDF
CIGTAGYPEKHFEAPNFGSDIRFLKEKVDRGADYIVTQMFFDNEEFFKFERRCRESGITV
PIIPGLKPLTTKAQLTALPRAFFLSIPEALSEAIHEAKDNAAAREVGIEWCLHQSRELMA
HGVPCLHYYSMGKAEAIRRVAAGLF
>A0A1A6LAD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio tasmaniensis|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQIAAL
>A0A6L8MW01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIHALNEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VHNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIINGLSPKEDFKYATD
LVSFIKEEAPQFDIIGACYPEGHPESPNAVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCILADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARTIHEATHALFKHYS
>A0A7Y9J900|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora corticicola|TrEMBL
MTFADALAAGTLLGDGAMGTLAQATGARAEGAVSELVLLAPELVGALHRRYLDVGADVIQ
THTYGASRLRLARHGLARQVGEINVAAARLAREARDEAGRPAFVAGSISPATSPRIAGPV
EAAAVRAALREQADALAEGGVDVLVCETFAHAEELAEAVEAVRAATDLPVIAQATFIEED
GGPVTTHGETPEDVARVVGALGPVALGSNCTLGPQGLLTVVRRLAAAVPDGIAVTALPNA
GLPHVVSDRSVRFASDAAHFGRYAARYVAAGARLVGGCCGTTPAHVAAAAAELARGPVVD
EPPALPIVRGVPLRGDDVAFLPLDDSNDVSLPQGAGLPRGEGAAVGAGREGPGRGAVARW
LDAPRRTPLLVAEVTGPGADDLDVHVARGRAALAAGAAALWAGRERARRRRTTTAGVAAG
VHEALDVDVALTVTSWNTSRMALQADLLGLDALGLHTIVTETGNPPVHADRAVRDGVWEV
DAVGLVGLAASLTAGVDADGARLAPTPFRVGVRVTSGTDDLDREMHRVRLKVEAGAEFLV
TRPVYELDRLRRVLAGAGVDVPVLLSLAPLSGFAEAEHLRHEVPDVVLPDAVLARVRAAG
EDPAPGLDLAAELAAEALAEGLVHGLVVRRPGPPELLAEAVTRLGAVLRASAGQLGRR
>A0A4J2B502|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALRGDIILDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A5K0WH92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nymphaea colorata|TrEMBL
KIADFDISVAAYPEVHPDAKDAQSDILNLKKKVDAGANRAITQFFFNVE
>A0A1F5EMS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Campbellbacteria bacterium RIFCSPHIGHO2_12_FULL_35_10|TrEMBL
MDFQNALNDKQFPIVLELSPVREPQNEENKRKIKEIIDVSGITAISITESPMGVSAMPPE
ELGSFIKNSSNLEVILHLSCKGRNRTQIKSRLESYYRKGLTNLLVVTGDYPKDSKPVFDL
DSVQVLDLIACLEQKNCGLNNKTISLFAGAVCSPLHPLQELQRQKLDLKIQAGARFIVTQ
VGYDFARLKLFKERFDKKKYDVPVLGNIFIPNLKLIDRIFRGEIPGCTISKGLYNFLSSS
SSENILKVYAWMMNEMRKMGFVGIHLGGPLVQNHQNLKKLLEYFQQLQKYPEEDFYRSIF
YSDDENSNYKIFPTTSFLEKTHYQLSSIAHKVLFNGGNKRTRILKKLSFMEHTVKAALYG
CKDCGECTLPDSAFLCPQSGCAKQLLNGPCGGTREGGWCEVYPTRLCFWVRVALRNPEFK
IKFTPPKQWGNIKGSWDTL
>A0A8H5J7W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium mexicanum|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVRHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMTSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFGLLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A6I3V0E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDL
>B2AGG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CCUG 44338 / CIP 107171 / LMG 19424 / R1)|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
DGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVKAGADSAITQYFYNADAYFRFVD
DVRALGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A1F1EZS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. HMSC075C01|TrEMBL
MHDNEPTGPTAAAGGRAGDLNSAETGTARRLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPADGISSGGYEGSAHESEAGRCQVAPRVRAVQEQTNPSECVLAH
VLESSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRADDVAGELRH
ADDLVRVIREVEADFFGDGRRHVTIAVAAYPATSDHIEAIEVLAAKQAAGADMAITQVFY
DAADYMALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSTLGSASGAT
LVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDA
VDRGYLQATPGRGPSFLRRGSPGAALSSLHPVQPHTTITKENA
>A0A514BPE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter alkalisoli|TrEMBL
MIPISFEFYPPKTDEQRAQLERTAKKLKTHSPEYVSVTFGAGGSTLSHTPEAIQNLSTAH
GYSAAPHITCMGGSRQEIRGLLKLYRAMGAKRLVTLRGDLPSGMVSPGDLRYANELVEFI
RAETGDHFHIEVAAYPEMHPQARDAHADMKHFIAKVRAGADGAITQYFYNADAYFRFVDD
VRAAGIDIPIVPGIMPISNFSQIRRFSEMCGAEIPRWVAQRMLAYADDAESIRTFGAEVV
AQLCQRLIDGGAPSLHFYTLNLAKPTQSVIERLR
>A0A0R2UCK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR92 bacterium BACL26 MAG-121220-bin70|TrEMBL
MFSPTNTNFIFTSETTPAVSTNLKQSIDRVLPLVGIADAVNVTDSPNSKTRLSSLLVAAG
IKELGLDVILQLTGRDRNRIAIESEVLGALSLGINKVLCLTGDKPSEGGPQVVNELDSAG
IMKLLTGMSNGKLSDGTDIKEPLPIYSGAADDLYLQKNNPEAINFLKIKIGNGAKFVQTQ
YCFDEEICTFYSDLLMANGKTDNLKVLIGMGPLKSAKQALWMRENLWGVNISDNIIARLD
ASNNPNKEGLMICHELISKLMDLPGIDGVHLMGPNCEHDSAEIIKLFR
>F0FV07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis SK678|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANELQIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A540UM59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIESLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A0J0URZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diaphorobacter sp. J5-51|TrEMBL
MSLSTAFPVSFEFFPPKTPEGADKLRAVRQQLYARRPEFCSVTYGAGGSTQAGTFGTVRE
ILAEGVSAASHFSCIGATKDGVRAQLAELKAMGVKRLVALRGDLPSGYGIGGEFHYASDL
VAFIRAETGRDFHIEVAAYPEVHPQARSSDADLQAFATKVRAGADSAITQYFFNADAYLR
FVQDVRRLGLDVPVVPGIMPIMGASQLLRFSDACGAEIPRWIRLRLQGYGDDVASIRAFG
LDVVTHLCEQLRREGVPGLHFYTMNQSAATLEICDRLGL
>A0A259E1H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. 17-62-19|TrEMBL
MNASYDQLREARTALDTPLFAGLPGDINVSFEFFPPKTDALMVQLWDVVETLAPFAPHFV
SVTYGAGGSTRDRTHGTVARIIKDAKLPAAAHLTCVDATKAEIREVAESYWEAGVRHIVA
LRGDMGAPGVPFTPHPEGYANAAELVAGLKTIAPFEISVAAYPESHPDSPSQQADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAAACGAA
IPAWMDGLFEGLDTHPASRQLVAATIAAEFARRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPTRPALEKAA
>A0A0M5KGY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gordonii|TrEMBL
MVRHHTPSLSFEVFPPNPAVGNEKIIQALREMQDIAPHYISVTASNNKFNIEETTVRLAD
FIYNDLKIPTIAHLPAVYLTKEMVSDTLQALDKVGVHKILALRGDIFPDVAPKDDFKYAT
DLIEYIKEEAPHFDIIGACYPEGHPDSPDRVSDIRNLKKKVDAGCSSLVTQLFFDNDRFY
DFQERCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLKS
AGLAYAIDQIVDLVTQDVAGVHLYTMNNAATAHHIYQATHTFFS
>A0A545A889|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Golovinomyces magnicellulatus|TrEMBL
MFISDKLAEAERSGQPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGNIA
QLTVEMVSIAQSHYGLETCMHLTCTDMGKEKVDDALSGAYKSGCTNILALRGDPPRQLEK
WTMTEGGFLYAKDLVKYIREKYGNHFDIGVAGYPEGCDDQDDPELLLDHLKEKVDAGGTF
IVTQMFYDVDNFLEWISKVRAKGISVPIIPGIMPINTYASFIRRANHMGCKIPPKWATAI
ESVKNDDSAVRSIGTGLVAEMCRKILASGLIHHLHFYTMNLAQATRMVLEELNLTPSERR
PLKTPLPWRQSLSPRRREEDVRPIFWKNRNRSYVMRTQDWDEFPNGRWGDARSPAFGELD
AYGIGLKGSNEKNRKLWGEPKCIKDVANIFVKYLEATIESFPWSETPITSEAEMIKNELI
DLNKRGLLTINSQPAVNGVKSSDPVFGWGPPNGYVYQKAYLELLVPDYLIDEILERVSRD
TDLTYHAVNIDGNLKTNTPNDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEAYRLGLD
WAHCHSALSPSRQLIENIMKKWYLASPSTLSNTQLTFYFIVNNDFHKTYGIYKVFEGLIV
NDLDKPYSACISNDESIPVTNGHKPNDPMTNGHKPKDPVTNGHKPKDSLTNGLGMNKPAT
NGPKLSAA
>A0A4V0C5N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gordonii|TrEMBL
MVRHHTPSLSFEVFPPNPAVGNEKIIQALREMQDIAPHYISVTASNNKFNIEETTVRLAD
FIYNDLKIPTIAHLPAVYLTKEMVSDTLQALDKVGVHRILALRGDIFPDVAPKDDFKYAT
DLIEYIKEEAPHFDIIGACYPEGHPDSPDRVSDIRNLKKKVDAGCSSLVTQLFFDNDRFY
DFQERCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLKS
AGLAYAIDQIVDLVTQDVAGVHLYTMNNAATAHHIYQATHTFFS
>A0A516WRC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. WB9|TrEMBL
MTFDSVRGRASEGWVTRTPSIVDRIRSSSDGRVPFSVEFSPPRDEAAEARLWRAVREFER
LGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWEKHPDGVEYAEDLVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSV
RRVLELSGSRLPAHLEKRLATAAGDGPEENRAAVREIGIDVATEMSERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSGVADPTPVTPARIS
>A0A7Y4BQA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio coralliilyticus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLIAAPHLTCIDASREELARIADDYWANGIQSIVALRGD
IPPGGGKPEMYASDLVKLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQV
>A0A7W2GDP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MD195_PC81_125|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETADHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A6I7HU48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciceribacter lividus|TrEMBL
MTREDRHPQGKRRLGISFEFFPPKSEEMEGQLWTTIEELAGWNPDFVSVTYGAGGSTKAP
TLTTVRRLIAETSLPTAAHITCVGATREEVRHVAEEFIAAGVRRFVALRGDPQGGVGAAY
APHPGGFANAAELVAGLKEIGDFDISVSAYPEKHPESPDVPADIDMLKRKADNGAARALT
QFFFDNDVFERYLERVRAAGVTIPVVPGIMLIQNLTQLKRFASLCGASIPAFLDERFAGL
DDQPQARAEVAAEVAAEQIEDLVRRGITDFHLYTMNRAPLVSAVLKQLGLGRDGEARSGA
AA
>A0A6D1IJ09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium wangchenii|TrEMBL
MTGKDIPGLEEARDTIPAGTKINVTFLGNEDLDMRVSAAKAVADMGFVPVPHISARRLSS
QGQLEEFLGRLQEVGATDHVFAVGGDPAEPEGPYPDSLSVIRSGVLQQYGVKEVSIAGYP
EGHPDIPSDVLWRHLEDKSAALKEQGLDAVILTQFAFDTDPVTAWIQAVRDRGIDTEIRI
GTPGPAGVKRLINFARRFGVGANAMIVKKYGFSLTNLMGTAGPDRFVTDLAALLAQNPAS
GNVRLHFYTFGGLLATSKWARDYAAARS
>A0A823HSN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDKAYLAVYPNASLPEVQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLESTKPVLEKEVRPIL
ELVPEEVEDEESGERLLDKVKERLTILVELDPPRTFDTSKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGRANEEGMTIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYVQNKQQLQIASK
>A0A0B2AYH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mumia flava|TrEMBL
MSVARVGDLVTGPDPTFSFEFFPPKSDAGERALWTAVRQLEPLQPTFVSVTYGAGGTTRD
RTVRITGRIAAETTLHPVGHLTCVGQSRDELHTVLRQYADAGVRNVLALRGDPEGGPGAP
WSSHPEGLDHGDELVALVASTGSFCVGAAAYPKGHREAASLEADAQVVAAKARAGASFAV
TDFFFLAEDYLSLVERVRGLGCAIPILPGIMPITNLAQITRMAQLSGHQVPRSVVARLEP
WVDDPEGLRAEGITIATELCDRLLAAGAPGLHFYTLNRSLATRQIYESLAATPV
>M4T8R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CNH189|TrEMBL
MTTFSFEFFPPRTAAGERTLWDAVRRVEALRPDFVSVTYGAGGSSRDRTIDVTRRIAAET
TLRPVAHLTAVGHSVAELRHIIGMYADAGIRDVLVLRGAPPGDPQGRWTPHPQGFTYAYE
LVELVRSLGDFVIGVAAFPERHPRSPDWESDVRHFVAKCRAGADYAITQMFFRAEDYLRL
RDRVVAAGCDIPIIPEIMPATDVRQIRRFAELSGATFPEDLAHRLETARDSPAEGHHIGV
DHATALAERLLAEGAPGLHYITLNRATAALDIHRAVRHSGSVGAH
>A0A7W8ACG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea endophytica|TrEMBL
MTFQLICEIEPPTKPDLKHVRHQIGTLSKIAHSFLIPDNHIGRATVSSVAVAHEVQAMGG
RSIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVFGDKPTSGNRTSDLTVRSMIDEARAF
SPDLKVGAAAGHRPLPAWKRAADFLFVQVSFDLDTLLRWREANPVDVPVYAGVMVLASES
HARRLAGAIPDIAIPDSMFTALAADRMAGVEAACEQVLAIRDSGAYDGVHLVPVARYRDV
ESRLFAELR
>A0A0P8A9P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saliniramus fredricksonii|TrEMBL
MQARSRATDGTPFRSVSFEFFPPKTPEMEATLWSSIERLAPLGPTFVSVTYGAGGSTRER
THNTVSRIVKETDLKPAAHLTCVAATREDVDEVVKGYHDAGVRHIVALRGDPVEGPGTAY
APHPGGYATSWDLIDGISRIGDFEISVSAYPEKHPDAASLDADIDALKRKVDAGATRAIT
QFFFDNELYLRYLDKVRARGIDIPIVPGIVPVQNFKQTANFAKRTGASVPDWLAARFEGL
EDDVATRKLVAAAVAAEQVIGLIDEGVEDFHFYTMNRADLVYAVCHLLGMRPDQPLQHAA
>A0A810MQQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polymorphospora rubra|TrEMBL
MSLGLPSVLPTSQPSIGDLIRAPGPTFSFEFFPPKDADGERLLWRSIRELEPLLPSFVSI
TYGAGGSTRDTTIAVTERIATETTLLPMAHLTAVNHSIAELRNIVGRLAAAGIRNMLLVR
GDPPGDPTGEWVQHPDGVLYAEELVRLVRESGDFSVGVAAFPYKHPRSPDIESDTEQFVR
KCRAGADFAITQMFFDADDYLRLRDRVAATGCDTPIVAGVMPVTRMGTIERSEKLSGAPF
PKALAARFERIADDPVAVRKLGIELAGEMCQRLIDEGIPGIHFITLNRSTATRDLWQHLR
AGVRV
>A0A0P0MC11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. 63ED37-2|TrEMBL
MSGLNLPISLEFFPPKTPEGAEKLRGVREKLYSLKPEFCSVTYGAGGSTQEGTFATVGAI
QAEGVAAASHFSCIGATKASVREELSTLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLV
AFIRAETGDDFHIEVAAYPEIHPQAKSPEADLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQAYGDDVESIKAFGL
DVVSDLCEQLINGGVPAIHFYTMNQSAPTLAIVQRLNSLTD
>A0A1A3K511|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium gordonae|TrEMBL
MEYGPCGGVRPDGQCEMRSGACTFTDIMPWNGPVRGMVRGPVPLVLTDFSCAPFDRDDVA
ATAAVLSSSCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDRNRVVLEQELRG
LRTIGVDTVLCVTGDGRGYDVRPDVTQTFDLDGLRLVSLAASLGAVPAVPETPTAPPVAA
RPARLVEKQRAGAALAVLNHVPFPDMIAEFMKSARAQGLSIPVIAAVAVFTDSVSAAVLQ
GLPGLELDPAVTERVLSSADPIAAGISAAVSEARSLLSIDGIEGVNVSGLASASGTRVGA
EIKAEVGRLIREGVA
>A0A410X8U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus hauseri|TrEMBL
MSFYHASQHEALNQNLAELNGKIDVSFEFFPPRTEEMENTLWQSLARLNTLKPRFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASHEELQHIAQDYWQSGIRHIVALRGD
LPDNSKKPQMYATDLVHLLKSVGDFDISVAAYPEVHPEAKSAQADLINLKKKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIIPGILPVTNFKQLTRFAGLTNVKIPGWMNKMFD
GLENDAETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPELVTA
>A0A1R0H992|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium mucronatum|TrEMBL
MKLIDKMKANIDEGNVFFSFEFFPPKTPQGLANLCDRLTRMKAWNPLFSTVTWCTGSSPS
NQCLEFSSNLHKELGMNTVMHLACTNMSKASINSTLKDAKNVGIQSILVLRGDEPSDVVD
RWPVTEGSSGNFKYASDLVEYIKSIPEYSDYFTIGVAGFPEGYISEKTDQDQTSDQNDEL
YWLSHKVNKGADFILSQVFYSTQKFMDWYKKCRDYGITVPIIPTLLPIQTFGSFKRIVNL
TKISVPSSLEDRIDRVKNDDLLVKQIGIDYCCHQINQLIDECNVPGIHFSTLNLENSIHA
ILSRTGLLKPLNTNPSSNPSGATSQAVSRIGDSSATWDEYPNSRWGDARSPAFFNESSYT
QINKISSLQISQWGIPKSLSHLNDLFSKYCKDEISSLPWTSDNINSRNSDFGKEVLAMLP
NFGIWPLASQRAIDGITSNDPELGWGPANGYVYQRSFIEFFATEAIASKILKLLENSTDY
SYYLSKQDPITNEPHIISNAVVSENIQSTALCWGVFPSSPVIQSALIDKLNFEYWSKEAI
QLWRVWADQLGVVDNDSKKFVDSVADSIWLINIIGNDYKRPDQLLQMLKEEFCA
>X1KGR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MTCRDRNRLALQADLLGAYILGIKNILALTGDEMELSDDLKAKPVFDLDSIGLLKAARKL
EKGYDLADNPLRGWPKFCIGAVLDPGAEPIEPEIERMQQKVKAGAEFFQTQPIFDIRVFF
KFLEKVGKLEVPILGGILLLKSAKMAKFMNENVPGVSIPEDFTHQMQKTEDPVQTSIQIA
SGIIEQIKGVCGGVHIMTVNWENKVPMVLKSA
>A0A732CU67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 18:z10:z6|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAAIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>X1M7X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MIMKSIKKSKFEKNLRSGKFAVTCEIGPPKGAEVEEIKEAAEYLKDVADGINVTDLQSSV
MRLGSLATCRLLKEWGLDPIFQVTCRDRNRLALQSDLLSAYVMGCITIFFTISPF
>X0TGF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
DFIQTQCIYDMNRFKDFMKQVVDMGLHERCKILAGITPLKSVGMALYMVANVSGINIPEE
MINRLRGAGKGNVASEGIKIACEQIQEVREIEGVAGVHLMAIEWEHRVPEIVTMAGLLPR
PKL
>X1MQC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
AGMARFMNKNVAGVFVPEELINKMAEAEDKTKTGIAIAANIINELRDICYGVHIMAIGWE
KKVPAVLDAAGL
>X1P9F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
ELVDPGRSPVEYEIERMWQKMEAGAKFFQTQSVFDAEAFSEFIWKKRSTPWKPRLRLLVS
SLTI
>X1LNV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKTKSNLERVLEAGHFAVTGEIGPPPGADPEVIRRKAKILKGNVDAFNVTDGQTAVVRMS
SWAACLIGKEEGLDPIVQMTCRDRNRIALQMDILGAAALGINNILCLTGDHQKFGNHPMA
KGVFDLDSIQFLKVVKDMRDEKKFQCGDEMAVEPNLFTGAAANPFADPFEFRVIRLAKKV
AAGADFIQTQIVYNVDKFAEWMKRVRDRGLHEKVKILAGVAPIKSVGAARYMKTKVPGMD
VPDSIIERLRGVPKERVSKEGIKLCVDIINQVRQIKGVAGIHLMAIEWEETVPEIIEAAG
LLPRP
>X1LQ32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
GKDLAGKELTQKPSFFKGAVVNPGADTEASYELQIIKMKKKIDQGAQFFQTQAIFDAEVF
KRFMERVHKENIDVPILAGIILLKSERMANYMNKFVPGVFVPEPVVKKMEGTGDKVSMCI
EIASRLIEEVKPYCAGVHIQALGWEKHISAVVKNLK
>A0A847A061|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp|TrEMBL
MENRFKEALLDPSKFPVTWELVPGRGAKEAAQEKCLAQAAQAAVGKIICALTLTDNPGGT
PAMSADFMGGEILKLGIEPLVHFTGKDKNRSQCESQLYALDRAGVRNLLVMSGDYPVSGF
QGRPAPVFDLDPVHILQLITGMNRGLTYPGIKGVVTHQPADFFPGAVVSPFKATEAEQMG
QYDKLKKKIAAGAQFIVTQLGYDARKFHEALLFMKQNYPQIPLVGNIYILPFGAAKMMNR
NDLPGSVVTDQLLADIDRERSEPDKGEGARILRAARMYAILKGMGYSGVHIGGHNIRYEQ
VEEIIRQGEALVPRWTDLVRYFDYPIDNGFYFFEADPATGLNRDTPADRRSRPPTAKVEC
AYGVSRFFHRLMYEPGKNLYGAMKALCKTVQGTRMEPLFHKLEHLTKVVLFDCRDCGDCA
LPDAAYLCPMSQCPKNQRNGPCGGSFQGWCEVYPQQKQCVYVRAYARLKKYGEESLLAGD
IVPPCNWDLYQTSSWINYYLGKDHTSLKQGGAGSPGTP
>A0A5E4F2Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prunus dulcis|TrEMBL
MKVIEKIQEALLEEKKVLFSFEFFPPKTEDGVENLLERMERMVAHNPAFCDITWGAGGST
ADLTLDIANKMQNIICVESMMHLTCTNMPVDKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQIQGGFACALDLVTHIRAKYGDYFGVTVAGYPEAHPDAIGTDGLASPEAYQSDLAYL
KRKVDAGADLIITQLFYDTDVFLKFVHDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPAEVTAALEPIKDNEEAVKSYGIHLGTEMCKKILAHGIRTLHLYTLNMEKSALAILMN
LGLIEETKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDLYPHGRWGDSRN
PSYGALTDYQFMRPRARDKKLVEEWVVPLRSVEDIHEKFKKFCLGKLRSSPWSELDGLQP
ETKIINELLGKINTKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKL
NALVEKCKALPSLTYMAVNKDGRWISNIGQTDVNAVTWGVFPAREIIQPTVVDPASFMVW
KDEAFEIWSRGWACLYPEGDSSRKLLEEVQNSYFLASLVDNDYIQGDVFAVFADF
>A0A3M7EPW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGIRNILALRGDPPRSDE
YNDPNNPLSEQDDSNKDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLVEKTAAGADFIMTQLFFDVEAYNNYEKRLRSHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLSRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTL
NLEKVVTQILERTGLIPPATPVIKTADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSS
NRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPINSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLKGEIEA
MPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSTDPIYGWGPKNGFVFQKPF
VELFLPSADWQRLKPILQSDDQVTYYAGDAAGDFQSSDENSVNPVTWGTFAGKEIITPTI
IEGDSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDA
LIAA
>Q2JMX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. (strain JA-2-3B'a(2-13))|TrEMBL
MALIPSSPPLSRFAQAIQRGEFLLTAEITPPKGSDTSTLLSLAQQLKGRVHAINITDSNR
AMARMSPLAASVLLHQAGVEPILQLACRDRNRLALQGDLLGASALGLRNVLALTGDPIHI
GDCPDARPVFDLESVRLLQLIQRLNNGLDCNGKPLPDGGTHLLAGAAVEPQSGSFSGLER
RFHRKLENGAQFFQSQMVTDFEQLERFMDKLGRPAGKPILAGIFLLKSAKNAEFINRNLP
GVKIPDEIIQRLANAAHPLEEGIRIAAEQVRQARQICHGVHLMAVKAEHLIPRILDEAGI
PPLTG
>A0A4R3JRG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalimonas umbilicata|TrEMBL
MKIIDKLQENKIHISFEIFPPKTDAGIEAVLSATEQIAKLAPAFISVTYGAGGGTSKNTV
QIASDIQKKMGVTSLAHLTCASSTKEEVLSVVDRLKAEGIENILALRGDIPEGLEFPETD
QYHYAYELIREIKKQGDFCIGAACYPEGHVENEHKEDDIAYLKQKVDCGVDFLTTQMFFD
NAILYNFLYRIREKGITVPVLPGIMPVTNSRQMTRICKLSGTVLPQRFHAILDRFGEKPE
AMKQAGIAYATDQIIDLIANGIDHIHIYSMNKPEVAAAIMTNLSEILR
>A0A7J8KCT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rousettus aegyptiacus|TrEMBL
MASNETAGRGHVGGGAFVTHVGDFRPLVPLPLATDSGAARLTCTPRPIRARPHSHRAAAA
RARSESLATAGNSAMVNEPRGHGSLNPRLEGSSSESSKDSSRCSTPGLDPERHERLKEKM
RRRMESGDKWFSLEFFPPRTAQGAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKETSS
MVIASTAVNYCGLETILHMTCCRQSREEITGHLHKAKRLGLKNIMALRGDPIGDQWEDVE
GGFCHAVDLVKHIRSEFGDYFDICVAGYPTGHPDTGSFEADLKYLKEKVSAGADFIITQL
FFEADTFFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSRLEVPQQMKDVIEPIKD
NDAAIRNYGIEQAVSLCQKLLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRLLPW
TVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLK
SKSPREQLLKMWGEELASEESVFEVFACYLSGEPNQNGCKVTCLPWNDEPLAAETSLMKE
ELLRVNRRGILTINSQPNVNGLPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVL
KKYEQRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFA
LWIEQWGKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWHVVEDTFELLSRPGSE
>A0A6H2VPJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPTAMTLADRVHSDHDIAPLEASKSYSDSIEKVLHFSGK
ARDIQDFERFLRQAQAANIQNLLLLTGDKLKEHNNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQVKSFLTKNNYSQ
QILVCVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQTGHTDHVYLRCALQILICKH
LGFAGIHLSACHKPEEQILLESYIEQYRHLELKALEELWNSLWQVTIGKEFSPEIARFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGLGRFIFKASFWENSLVAKVLIKTEVLSKHSLV
GCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQT
EILQEKLIPTVPLETRGTSSWKNWYLAT
>A0A7J4VYP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neorhizobium sp. P12A|TrEMBL
MSQIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERASVF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANMMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNGKFLSGRKLTKPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGFHEKCFILVGV
GPLASARTAKWMRSNVPGVHIPDDIIKRIEGAEDQKKEGKQLCIDIINEVKEIEGVAGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREANRGDELVAERMEHIREGKEENQQEMAEIAA
HHVPTH
>A0A8I1KXY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGEHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDHSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A3B9Q0P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MKKPAILTCTIEGDFMKREDFLQKIEGNKPIVADGAMGTLLHERGIGFERCFDELNLTNP
ALVGSIHQEYIHAGAEIILTNTFGANRYKLERCGLEELLTEINQTGVDLARRTIRASFKE
ILIAGDVGPLGVRLAPFGRVQVEQAREVFREQIQALYDAACDLVVIETMTDLYEIREAIA
AAQEVDAELPIVASMTFTRDDRTLLGDDPQKVAQKIFSYGADVIGINCSGGPNQLLRILK
KMKKELPDGIFWVKPNAGWPEQISGRIFYPASADYFGEYALAFWQAGANVIGGCCGTTPA
HIRSIRQALDNTQEKAISNGLTLEMVEDEMMEQESSEPSRYAQKLGNGDFVYSVEMQPPR
GLATKKIIAGASMLVDSGADAINVADSPMARMRMSPWAVCNLVQQKVNVETILHFPTRGR
NLLRVQGDLLAAHALGVRNVFVIMGDPTAIGDYPEAMDNFDLAPSGMVKLIKQRFNLGID
QSGSDIGQPTNFFVGCALNLTANDPQREIEILQRKIHNGADFIITQPVYDARCIPAFKKA
YKEIYEELHIPLIIGIMPLVSARHAAFLHQEVPGISIPEAIHNRMQTAEEKGSGPQEGIQ
IAVELIQKVKEMAEGVYITPSFSRFDYVAEIIERSK
>A0A6A7RQT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter phosphatis|TrEMBL
MTQNKRTFSLELFPPQTPEGAAKLRAARARMAALKPRFFSVTFGAGGSTRDRTLETVLEI
QQEGYQAAPHLSCIGSTRESIRSILEQYRANGIRHLVALRGDLPSGMARPGAFRYANELV
EFIRAETGDCFHIEVAAYPEYHPQAKNPQDDLQSFKRKLDAGANSAITQYFYNFDAYAHF
IDECQAIGIDLPIVPGIMPIAGYSSLARFSDTCGAEIPRWIRKKLESYGDDSASIRAFGL
DVVTGLCERLLANGAPGLHFYTLNQDALTAALWQRLRLS
>A0A6G3RRL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID339|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTFSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGDWIAHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSPDWESDTRHFID
KCRAGADYAITQMFFDPEEYLRLRDRVEAAGCATPIIPEMMPVTNVRQLDRLPQLSNAVF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHQA
>A0A3M9YP72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyrobacter sp. IPPAS B-1204|TrEMBL
MTPTLSQLHEYRTATDTPLFSGLPGDVAVSFEFFPPKSEKMEEQLWDAVTQLRPLGPSFV
SVTYGAGGSTRERTHATVARIIGEAKLPAAAHLTCVAASKAEIRDVAEQYWEAGVRHIVA
LRGDAGEPGAPFTPHPEGYASAAELVSGLKAIAPFEISVAAYPETHPDAASPQADIDNLK
RKLDAGATRAISQFFFSPEAFFRFRDACAASGIDAPILPGILPVTNVAQARKFASACGAE
FPAWMDGLFEGLDEKPAARQLVAATVAAELCRRLYAGGVRDFHFYTLNRPELAYAICHML
GKRPVGEAA
>A0A3R8ITX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutaceae bacterium TAV4|TrEMBL
MSASNPPISALFPEHRPLRSLEFFPPKDDAGVESLRAAATALRKAPWDFVSVTYGAGGST
RQRTTQVSRILKDELGFTVMPHLTCVGHSRAELTALADQIHADGFRNIMALRGDPPKGSA
TFTPAADGLRHANELVALLKQRHPDFCLGVAGYPEKHPEAVTLEADLDALKRKIDDGASF
VTTQLFFDNAIYQKFVEKCHARGIHVPIIPGIMPVLSIGQIKRIATLSGTQLPPPLARRL
EVAAEDPDVVEIIGIDWALDQIRGLLAQGAPGYHLYILNRAKSALALAAGLAA
>A0A0R1SFZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus versmoldensis DSM 14857 = KCTC 3814|TrEMBL
MAYAIDQIVDLVTNDVDGIHLYTMNKSDTARHIYDNTISLFAQPTDNLTRS
>A0A1H1YMV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 2114.2|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTNFVD
KCRAGADYAITQMFFQPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A0R0RYH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGIHIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVNLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>G4CR27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria wadsworthii 9715|TrEMBL
MSLPKLSFEFFPTRTPEGRAKQVITRKQLSQYAPDFFSCTSGAGGSTREGTMQTIQDILS
EGIAAAPHLPCIGMQPQEVVDLLNEYKALGIRHIVALRGDIPSGMGAGMDGLFYANELVS
LIKNEFGDHFHIEVAAYPEFHPQARSAEDDLNNFVRKVKAGADSAITQYFYNTDAYFRFV
DDVQGRGVDIPIIPGIMPIASFSKLTRFSDTCGAEIPRWLRLKLQSYADDTAAIKSLALD
VVTEMCERLLREGAPGLHFYTLNQAGLVSTICQRLGY
>A0A2M7AZ74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG06_land_8_20_14_3_00_38_11|TrEMBL
MKLTELFPKKFVVTSEIGPPKGWQIEKCLNEAEHLKGKVDAMNVTDNQSSVMRFGSLATC
HFLKDRGMEPVFQVACRDRNRIALQSDILSAAAFGIENLLLLTGDHTTLGDHKDAKPVFD
LDAVSLIYAVKKLEEGVDLAGNKLDGVPPKFSIGAVVSPCSDPVEPQLIKMEKKVKTGAE
FFQTQAIYEVEKFVKFMEKAKQFGVPVMAGIVILKSVGMAKYMNENVAGVYVPDNLIEEL
KKDKEKTKSGQTGIEIAARLIKELKPYCQGIHIMPLGWDDKVPKILELAGL
>A0A259LEW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 39-66-18|TrEMBL
MQFDAERREDPRHEVAPAARSDAKALAMLVERLSIEVSPKEVLHSGHALGVPAGTRTFIT
RLPRGSLEDTRAAAVALRQAGLQPVPHVAVRTVPDAGTLERWLRFFVRDAGVEEILLIAG
SQERPLGAFGETADTLASGVIEGSGLRAVSFAGHPEGHPVADADELQRAIDVKNEFAART
GLSCALVTQFFFDATPVIAWERRLRERGNRLPIDPGLHGVTGVPSLLKHALACGIGASVK
ALSAHGSGGILQFAQIRTPDALAQALAAALANDPDSLFRGFHLFPLGGLAKTVDWMAQVQ
RSAAGTSLAEGVPGAGAEDGIARPPQ
>A0A557STA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosocosmicus arcticus|TrEMBL
MNIIYELNPPKILNSYRIDIALLNQELLKFLNRARIISNFTKYIHITDSVLGIPRFSSIH
AAQMMMNNLTNVALNISCSVRTRDRNMNSIIQMVTDAVLLKIRGLLFIQGDKPAFEESEN
ASSLSNPTDVIKLLTSIGFDKLIDLDLSIPNKISNQKVFQKKVNSKPHTFITQSINSIQE
IRDLKDLIKPKNIQLIPCIMVPSVKNERAAAMIGLDWSEYQDNFLGFLKEVYQETDHILI
TSPNSFDEGIEVLKKIV
>A0A7K0KB70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella mizrahii|TrEMBL
MNVIDILNDSSRPNGFSIEVLPPLKGNGTGALFRNLDKMCEMKPLYVNITTHHSEYVYRE
LEGGHYERQRIRRRPGTIAIAAAIQKRYGVMVIPHVICSGATAEDIEYELIDLQFLDINN
VLLLRGDKAKDDKTFKPVPGGYAHTTQLIEQVNRFNEGFFVDGTPIKHPGDPFHYGVAAY
PEKHEEAPNIDMDMAYLKQKQDMGADYAVTQLFYDNRKYFDFVKRARAMGITIPIVPGIK
PFAKCSQITMVPKTFHCDMPQELAAEAVKCKTDDDARALGIEWTVNQCRELFAAGVKDIH
FYTVSAVDSVVEVAQQLM
>A0A1X9MDT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus krulwichiae|TrEMBL
MNFLKKLAQQVLIGDGAMGTLLYEQGVDQCFEEVNVTEPDKIVRAHREYIEAGADVIQTN
TYAANRLKLEKYGLQDRVSELNNKAVRLAKEAAQGEVYVLGTVGGIRRFQLEEWDLTEIK
AAFKEQMTELVAGGIDGLLLETFYDLEEAKVATSLARQITDIPIIVNLSIGEVGVMNGGI
HVSDAFDQLKSVGADIVGLNCRTGPFHMLRSFETIPLKAGVFFSAYPNASLPDYRDGRVF
YQSNADYFKAMGEKFIQQGVRLLGGCCGTTPEHIKAFAEVREKVAPVTTKKVRSIVTIKE
MSETRRVQDPLPEIVEKRKSVIVELDPPKKLSTKKFMDGARALKDAGVDAVTMADNSLAS
PRVDNLALGAMIKEQIGVRPLVHVTCRDRNLIGLQSHLMGLHALGIDDVLAITGDPTKIG
DFPGATSVYDVSSFQLISFIKQLNEGISFSGKELGQKANFSVGAALNPNVRHLDKAVKRM
EKKIDSGADYFMTQPIYSSQQIEELANETKHISKPIYIGIMPLTGTRNAEFLHNEVPGIK
LTDDIRHAMAACGEDREASTKEGIAIAKSLIDTALAHFNGIYLITPFLRYEITVELTQYI
ESKKQAIYR
>A0A7T3K952|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MNIRHIFNKKKLVFSLEVFPPKIDSPLKTIYKALNELSNLNPDFISVTYGAGGSLVNNKT
AEISSLIKNVYNIEALAHLTCISAKKDDIDKITERLTSEGVSNILALRGDDNGVQRNDFN
YASDLVEYIQNKDKFNIISACYPEGHIENKGLDIEIENMKRKIDNGTTSFISQLFFDNNS
YYNFLNKVRSKGINVPIQAGIMPVINKKQIERITKLCGAKIPPKFAKILDKYEHNKEALR
DAGIAYAVDQIIDLISTGVDGIHLYTMNNPYVANKINDSIKLVLRTINNECSA
>A0A5K8AB61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina ovata subsp. ovata|TrEMBL
MHLKNKFDVGKFAILAEMQPPKGVNVSTMVNSATRVRKAVDAFLVSEMGNAVMRMSALGG
AMILQSRGMETIMQANCRDRNRIALQADLLAAYGCGIINVMGVAGEDPSLGDHHQTKAVH
DIDLMTLYRAIAVLQTGKDLAGNELSGAPDFFVGGSVNARAAGDELENVLARLNEKIDAG
VNFFIAPPVYDVGAFAAFMEKVDLKTTRIIPTVMLLKSVGMARYLDRHLNVTVSQDLIKR
MMHAPDKATESLAIAAETIKAIKEAGFAGVLISAMGWEDKLEKLVDLI
>A0A6I2UCK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerovibrio slackiae|TrEMBL
MGRISVELVPRSPEGLREDLQMIKDNIHGVDLINIPDLLRFETRSWQGAAIAQDFYPAVM
PHIRAIDVDLTQPLAMRPELRQSGITEVLVIEGDPPQDMSHKFYPTVTTDVIQKFHQEMP
EVKVYAGIDQYRGSMRQELYRIQRKLQAGAVGFFTQPFFDMRLLEMYADMLQGQNVYWGI
TPIASERSKSYWELKNNVIFPRDFEPTLEWSIYFGRKVKGFIETTGDNLYLMPIKGNLQA
YLEGILGSQPE
>A0A3D4VUR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MDIREYIKEHLLIFDGAMGTYFMKKSVNPQEKCELANLTQQEVIYSIHREYIEAGCKAIK
TNTFGANRINFGGDEELLKKLIKSGYEIACKAAGDDIFVFADIGPVEEDGVADGFEEFKF
VVDCFIELGAKNFLFETLSNDKHLEKIAKHIKQKVKDAFIITSFAVQPDGYTRDGYFGRD
IFKRMVEVKNVEALGLNCVSGPFHMLHYLKELNLKNVTLLVMPNAGYPTVVNNRTLFDAS
PEYFGLQMADIVRQGAAIIGGCCGTNPEYLRETVIKAKQVTGDEIIVSSVKDGEKLDNLK
RENHFMNKLERGQKVLAVELDPPENADITKFITNAKKIKDVGADIITIADCPVGRPRVDS
SLLACKLKRELNMDILPHITCRDRNLNATKALLLGLNIEGVDNVLVVTGDPIPSAQRDEV
KSVFNFNSRMLARYIDNLNQTIFSSPFGICGALNVNAPNFNIQLKLAKEKIENGVKVFLT
QPIMTQKGLDNLKYAHEELDAKILAGIMPVVSYRNACFMNNEISGINVDEKIIKLYENKT
PEQCRKLAVKVSTYIAKEVVDYCDGLYIITPFSRADIVCDIVNAVKDAKILKL
>A0A1Q3AF81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygosaccharomyces rouxii|TrEMBL
MRISEKLQSHRSKSTKPTFSFEYFVPKTTQGVQNLYDRMDRMYQSTLPQFIDITWNAGGG
VLSQLTTDLVETSQSVLGLETCMHLTCTNMPVSQIDDALESARLSGCQNILALRGDPPVN
QDSWKPVEGGFQYAKDLVKYIRERYGDYFDIGVAGYPEGHPETAGDDETLLNHLKEKVDA
GANFIITQMFYDGDIFIKWCERVRAKGIDVPLIPGIMPITTYAAFLRRANWCDVHIPQEY
FNRLDPIKDDDQLVREVGTDLVISLCQKLLDSGYVSHLHIYTMNLEKAPQMILDRMDLLP
GHDEPLDNHLAILPWRKSLNPQRRNEEVRPIFWQRRPYSYVARTSQWSVDEFPNGRFGDS
SSPAFGDLDLCGASLIRQSGKRSLELWSAPTSMQDIAQLVINYLRGELQYLPWSDTSLNH
EVDDILPELVALNQRLIITVNSQPQLNGVKSNHPVHGWGPRDGYVYQKMYLEFLLPKEKL
PKLHDCLVNDVMLTYFAVDHDGNLTTNHHDGSKANAVTWGIFPGREVLQPTIVEKVSFLA
WKQEFYHICEEWKLNFINNNCDQSIKVLQHLIDDYVLVNIVDNDFISPENRIFNLLSSI
>D0S1Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus RUH2202|TrEMBL
MFRCLQGFDMTKRIPISFEFFPPKTDAGAEKLRIVHQELQPLNPDFFSITYGAGGSTRER
TLAAIDDFNGKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGE
LPYAQDLVRFIRQHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFF
NPDSYFYFIERLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDS
ESIKAFGHEVVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A351XJS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
TQMFFDNSIFYNYMYRLREAGIMVPVIAGIMPITKKSQMARSIQLSGCCVPAKFKAIVDW
FGDEPLKMQQAGILYAAGQIIDLVANGIYHIHIYTMNNPMVAEGIMNSLSEIIGK
>A0A0F0GU49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL F-4428|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMADWVAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
SDVKERMLAVKHDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A3C0VTN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKISEILKSGQPTLSFEVFPPKTSDGFEKVKCATDAIADLKPDFMSVTYGAAGTTKGFTT
EIAASVNSKGVASLAHLTCVNASRESLDEQLEAFKAQGIENILALRGDLPEGVASTADWK
YKHASELIPVIKEHGDFCVGGACYPEVHPESADSW
>A0A022W5P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton rubrum CBS 288.86|TrEMBL
MHIKDKLALAEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMPRERVDDALQSAFKAGCTNILALRGDPPREKEA
WEQTEGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFLDWVKKCRQAGIKVPIIPGIMPISTYAAFIRRTNWVKCAVPKGWMEAL
EPVKNDDAAVKQIGKALVSEMCRKLLENGINHLHFYTMNLAQSTTMVLEELNLKPSTETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSVRDLSDIFVRFLEHKLDRLPWSESAITQESEIIKDDLID
LNNRGFLTINSQPAINGAKSSHPIYGWGPRNGYVYQKAYLELLISPALIDEVVRRIESNA
DLTYHCINKDGELKTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSASRKLIQNTMDTWYLVNIVNNDFHKTHDIFDLFKGLVLKDIDTEVSGTQQATE
PAENGTHSEDPASKSEKQAVSAN
>A0A4Q7DFV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. SO1|TrEMBL
MTASPESASTDPACPPTTPFSFELYPPKSDAAATALHTTIDALAAAAPDFISVTYGASGS
SRTSSLDVLRYILQATRVDPMAHLTCVGSSHAEASSLIREFLDAGVRSFLALRGDPPEGL
AEGDTFLGDLQSAGELVQLIHRVQAERVPYRETPIPGLPRARAVKTEHEHVRIAVAGFPN
GHPRSRSTAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPV
TSPGRLRRILELSGEDLPSELAIQLEVEPTAEGQREIGIDHAVTLARKLIAGGAPGLHLY
AFNQHETVLTVLDRAGALAPGRSQPAPPTSPSASLGVHTGINSTKDY
>A0A127JUA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramlibacter tataouinensis|TrEMBL
MTLSISLEFFPPKTPEGADKLRAAREQLYALKPEFCSVTFGAGGSTQEGTLQAVSEIMAE
GCPAAPHLSCIGQTKDSIRERLAAYSAAGVKRIVALRGDMPSGYGLGGEFRYASDLVAFI
RSETGRQFHLEVAAYPEMHPQSKSPTSDLDAFAAKVEAGADSGITQYFFNADAYFGYLNE
LHRRGIRVPVVPGIMPITNSSQLMRFSDSCGAEIPRWIRLRLQGFGDDSASIKAFGLDVV
SQLCEHLKAGGVPGFHFYTMNQAKATAEICRRIGLAP
>A0A7W1UYL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
SELVTQISNLNKGIYLDEDLQNSSCTDFCIGVAGYPEKHMEAPSMDSDVHFLKQKIKNGA
EYIITQMFFDNKKFFDFVAKCRASGITVPIIPGLKPIATKKQLNLIPHRFKVDLPDDLIM
EVVRAKDNEAVQQVGNSWCVQQSKELIAAGIPVLHYYSMGKSENIKSIASQLF
>A0A7V4SYA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Margulisbacteria bacterium|TrEMBL
MKVCELLKVHQPTLSFEFFPPKTKEQEEELYQVITQLKIFSPHFVSVTYGALGTTRQKSF
FWAKEIKARFQIEPLAHLTCVAATKEDITQELQTLEEIGVENILALRGDPPEGQKDFVPP
AGGFRFARQLIEHIKTVAPHFCLGVAGYPEGHPEAPNLEKDIEYLKQKIEAGGEFIITQL
FFENRYFFDFQERCRRRGITVPILAGIMPITNYKQIRKMTKICGATIPPELLAKLEKYQA
DEKAIKEIGVEKATSQCQELLKAKVAGLHFFVLNQAEPVSQILREVL
>A0A7Y6PMN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kofleriaceae bacterium|TrEMBL
MADTSRPLSEAIANGPLLLDGAMGSLLYERGVLHTRSYDELNLSTPDLVRTIHADYVAAG
AELIETNTFGANRIALARHGLVEQGTAINRAAVELARAAAHDKAYVAGAVGPTGVKFHIA
TVAERRLARFALAEQIDTLVLAGVDAIMLETFTSILEMEEAIHVAKERGPKVPVIAMMVF
DATCRSDGGLGPAEIADRLIAAGADVVGGNCGVGPAELYQVVTNMVGRGKPVIAQPNAGM
PASVEGRTLYVANPEHFGVFARRMVKSGVMLVGGCCGTTPEHTRAMLGAVRMMRGEKIEE
RPGTKSSPTIQITRGPSPAAKAPLADRSRLGGRIARGEFVVSVELTAPSGLDMTKTKQQV
SQLSEGGVDVVNIADGPRASARMANVAVCAKLAAETNVEPILHVCARDRSFLGLVAHLLG
AGGLGLRNLVIITGDPPKMGDYPFSTPVYDVDSVGLLRIAAGLNAGVDPAGKECEPTRFV
LATGAEPAAHDRERELRRLEEKKLAGAELVMTQPVYDPRTLERFLDDAEPLGLPVMVGIL
PLASHRNAEFLHNEVPGMSIPAEYRERMAKVGGGPAARAEGIRIAQEALAAVKHRVAGAY
VMPPFNRVDSALTVLEVARDRWQPAR
>A0A0C2HXN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geoalkalibacter ferrihydriticus DSM 17813|TrEMBL
MTVYPSRSQRFLDLLQQRVLVGDGAMGTLLYQRGVALDANFEHLNLVRPQLVLEVHQDYA
AAGAEVLETNTFGANRLRLGAIGLAHKVAAINTAGARLARQVAGEERFVAGSVGPLPPAR
GEEQDLSETQKGEILREQMSALAEGGVDLFILETFSSLADLQLALGIAADLGLPASAQLA
FLEGGRTRDGVAAEAAVRALEQADAALIGANCGAGPRDLLTVLRQIAPLTQRPLAAYANS
GFPQYRDGRFIYLATPEYFAAMGREMALAGATLIGGCCGTTPDHIRALAQSLNQLTPAAR
PSAPARPHATQPSISPKPAAPHFLADWGRRPIITVELDPPRGLNCDKVLGAAEKLRAAGV
DAISLAENPLARIRMGNLALACRMQEQTGVPVIAHVTCRDRNLIGLHSEMMGAHLLGIRN
LLAVTGDPVSLGGEAGASSVFDLNSIGLLELLTALNEGINLFGTELEGRSEFLLGAAFNP
NVRHMDGQIRRLEKKIAAGARFVQTQPVYSHEILDKMLTLTDPLEIPVLVGILPLVSERN
AEFLHNEVPGISLPDEVRKRMRGLRGEEGIREGLAISGELVAAGRGRVGGWYLMPPFGKV
DLALALMKEIRRNAEH
>A0A525JR85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp|TrEMBL
MTIDLSELDEQRSVESSVTSQKVGYHNQIRESLQKGTFCYTLEYVPDLSRANPGVMDELR
RNSELLGRDPRIAGVNIGDRVKSLDSLDTITCGCVAAAASGKVPLLHLAGKDRTPDQARA
VIARALSQGLENMLLLTGDGITEQRAERFRYQESINAIRDAKQMAPTCLVAGAISPFKYR
EEELANQYLKMAKKVNIGVDYLITNCGWDMRKLEELAWYRDARGFRTPLVANLLMPTMGW
ARGIHSRRLPGVFMSDDLFNKICEEHAQGKAEAKRMAWNRLALQIVGAQHLGYAGVHMSG
VDRYEDLCATIETAENLARKLPSLEAWKEAWDEAHRLADGRTVEFAPAGGLYLFDTKPAP
KSLSHLPTFGCAKPSEEELAKYSRMKSLHHAVFEEGTVGASVMGLAVRALDRTAIGRSAL
LQLEKTTKHAALGCETCGFCRIEYLFYNCPETCPKGLANGSCAGTDENTCEFKDRECIHN
RKYRLAKSEGRLDELERTIIPPVEGTRGTSSWVNHFKGKTPKVL
>A0A2E7TUR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MDSKNSPFSIEFYPPRNAEGESRLDAVHAELAKLNPDYFSVTYGAGGSTKSGTRKLVMKY
QTAGSQVAPHLSFGGTDEQEVLELLQTYKEAGIKRIVALRGDIPSGSGAPMYYRYANELV
KFIREETGDYFHIEVACYPETHPEAKNFSSDVAFFKQKVDAGANSSITQYFYNVDAYFRF
VDYCDSQGINVPIVPGVMPITNFDNLKRFSAKCGAEIPLWLGKRLEDFGDDVTGLKQFGQ
DVVTELCYDLLQGGAPGLHFYSMNLSKSVSQIWSELGLQDRNT
>A0A2M6ZYH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG07_land_8_20_14_0_80_51_10|TrEMBL
MANSLFEEKLCSDKFLVTTEVGPPKGADVSEMVHHIDRLKDKVDAINVTDHQSSVMRFPS
LGGCLLIKERGGEPIFQITCRDRNRLALQADLLLAYSRDIRNVLCLTGDSIDIGDHPEVK
PVFDLESVQLLRMIRTLESGKDAAGNDLKGAPQFCIGASVHPTADFIEPQLIKFEKKVAA
GAQFFQTQGIYDLDTLRRFMQYASQFNVKILAGIIVMASARMARYMNDNVPGITVPQDVI
DELATAEKGKGLQKGIEIAARLIKGIKEERLCHGVHIMAVGNERIVPNIIEAAQLNGMHP
>A0A3C2AM54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVIDHLNAAKGTLFSIEILPPLKGKSIDSLFNGIEPLLEFKPSFIDVTYHREEYVYKKR
AGGFLERVSIKKRPGTVGICAAIMNKFGIDAVPHIICGGFS
>A0A2E0AYG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastopirellula sp|TrEMBL
MVSQVKAQFGLPVASHLTCVGSTREDLIRYLHTARDRGVDYVVALRGDPPQGQDAFTPVA
GGLSYANELVTLIRDEFPDFGIAVAAYPEVHQEAPNADVDLQNLQRKIDCGADIAITQLF
YENQDFFTFRERYEGLGISAPLVPGILPVTNLAQIQRITSLCGAQLPDTFVQRLAEHEDD
DEWQFQVGVEFATAQVRELLDQGVPGIHFYVLNKSQATSAVLQGLEWSRVNVA
>A0A523W7Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Stahlbacteria bacterium|TrEMBL
MLREKLNKHKIITVEVLLSTTPHLDNLVNAIKPLKDYIDAVNIPSNPLGRLKPDALCFAH
LIQEKMGIETIPHFVARHFTSLGFESHLLGAKALGIENILCVTGDSPVGGRSTFELNSPK
LLDIASSLSNGLTFARKAIEPIDFCLCTSFNPNVPNVNGEFIKIKEKCRCGAEVFFTQPI
FKPEVFLNILKEFRQRHKDIKVVAGLSFLYTKKRAFRLMKFLGIPYEYINNIEEKDETEI
LLEIAEKLKDYVDGFYIIPIAKYHNALDLIRKIRK
>A0A4Y6QRN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. NIBRBAC000502771|TrEMBL
MSPPSLIDAHPQLSETAPVALSYELFPPRSPAAAETLWTTIRELETTEPDYVSVTYGASG
SNRDTALELINRLLVETTLRPLAHLTCVGNTPQELAAIIGDLLDIGVRGILALRGDLPQD
GAPPAAGSLRYAQDLIDLIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEDHDVEVLL
AKQRSGADFAITQVFFEASQYEDLLTRARRAGVTIPIIPGVMPFTSLRRLKRLGELAGVE
PAPRLMDRLAAADNDIERLHIGVDATVDLANAALDAGAPGLHLYTFNEHQSALEVLDKLA
LPRHNRSSHARAAAARTQLAS
>A0A316R8Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKLTDKFTDGRTLFAFELLPPLKGQNIESIYSAIDTLREFSPSYINVTYHREEIKLVERE
GGLLERRVVRKRPGTVGISAAIQARYSIDVVPHLICGGFSADETEDALIEMNFLGIDNVL
ALRGDNMRGEHTFRPHEGGHCHASELVSQIASMNRGEYLSGEVEHCAPTDFCIGVAGYPE
KHAESPNVKSDIARLKEKVDAGANYIVTQMFFDNSRFFSFVDECRAAGIEVPVIPGLKPF
STKAQLSLLPQVFGVNIPEELASAVDKAPDNAHVRNIGIEWAVGQCRELIKAGVPALHFY
SMGRPDNIASIASRVF
>A0A1Z9LBD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium TMED188|TrEMBL
MDRPPFRHANPTGGGLILHSGPRESRPGLTTALQRAIETGQQVLTAEVMPPRGVDPSHML
EMAGCLRGRVHAINVTDGSRAVMRMSSLASCRLLLDAGLEPVLQMACRDRNRIALQADLL
GAHAMGIRNLLCLTGDPVRAGDQADARPVNEFESVKLLQQVHALNHGVDPVQGDLPDGAS
ELFAGCAADPQSPSWSGLQRRLQRKQAAGARFVQTQMVMDAFALERFQRELAAPLMLPVL
AGVFLLKSAKNARFINRVVPGACIPDALIRRLEESADPAMEGVAIAAEQVKQYLGIVQGV
HLMAIKAEQRIPLILDQAGISSRPG
>K8ZYU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WC-141|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPVAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELEALEELWHSLWQVT
TGKEFAPEITRFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALVAK
VLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAIEQTEILKEKLIPTVPIETRGTSSWKNWYLATEA
>A0A845WHR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO4G3|TrEMBL
MTNPTKNSFRTAVESGEFLITAEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQQGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFEK
KLEAGAEFFQSQLICDFDRLEKFMDQIAAGTNKPILAGIFLLKSAKNANFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSPVNDFVCK
>A0A851U6M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elachura formosa|TrEMBL
MVNEVQHTCSASSSSKSDGSSSGSESSKDNSRCSTPVLDTDRHERLREKMRRRQDAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A218Q7Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nodularia sp. NIES-3585|TrEMBL
MQDTQNPTVLNSFRHAAQAGEFLVTAEVAPPKGVNVTHMISMAATLKGRVHAVNITDGSR
AVLRMSSLVASVILLQNGIEPICQVACRDRNRISLQADLMGSHALGIRNILALTGDPVKV
GDHPNAKAVFDLESVRLLQLIRKLNQGVDYNEKPFTDGATDLFAGAAVDPQCASWSGLQK
RFERKIEAGAQFFQSQMITDFERLEKFMDTVAVNYEKPILAGIFLLKSAKNAQFINRCVP
GVNIPQHIIERLAKAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLITPILNLAGV
PAVNQVLAK
>B1LVN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1)|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTDEMEKILWNSIERLAPLQPSFVSVTYGAGGSTR
ERTHNTVARMVRETGLKPAAHLTCVDASRDEIDAVVQSYWDAGVRHIVALRGDPAEGVGH
AYRPHPEGYASTAELVQGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQA
ITQFFFENEIYLRYLEKVRAAGITIPIIPGILPVQNFKQAANFARRTGASVPYWLAARFE
GLEDDVETRRLVAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AKAAA
>A0A328BFY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium kunshanense|TrEMBL
MSPTDTALGPIARAGVGGQPRPNVSFEFSPPKTAEAEEKLWEAIRRLEPLNPSFVSVTYG
AGGSTRDRTHRTVLRMLQETALKPAAHLTCVEASRAEVDEVIRDYWASGIRHIVALRGDP
PGQIGGAYTPRADGYANATELTAGIRAIGDFEVSVGLYPHVHPESPSIDHDIDVLKAKID
AGATRAITQFFFDVDGFLRFMDRVRKAGVTIPISPGIMPVTNYAGLKKMSGPIGIQLPGW
LGNLFDGLDKDPETRRLIAASVASEMCARLAEEGFGDFHFYTLNRADLTYAICRVLGVRE
PAPEPKEAAA
>V7FFA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSHC420B00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVIREFADMGVKRFVALRGDPAEGVGA
AYRPHPEGYANGAELVDALKGAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEVEAA
GSAAA
>G0GFY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaeta thermophila (strain ATCC 700085 / DSM 6578 / Z-1203)|TrEMBL
MVRDLFRQGRTLFSFEFFPPKTSSGWESLFATVRELALLEPDFMSVTYGAGGSSREKTHE
LVVRIRQELGVEAVAHLTCVGSTEEEIVRILEAYDREGIHNILALRGDIPPSLAHHPNPF
GVFPHAVDLVRFIKARFPHMCVGAAAFPEGHPETPNRLKEMEHLKHKVDAGVDFLVTQLF
FDNRDYYDFCERCELAGIRVPVIAGIMPITTRKNMERMAELAAGMHYPARLLRALSRVTD
DEGFFHVGVHWAAEQIRDLLDHRVPGIHVYTLNTSRAVKAICETLGIRHLPQLG
>A0A1I7CZ90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. YR577|TrEMBL
MNPPRPPQIDENPAGIDLPLDRLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
GAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMERARDLGLTDKVF
VLCGVGPLASAKTAKWIRSNVPGIHIPDSIIARLEGAQDQKKEGKQLAIDIINEVKEIPG
VSGIHVMAYRQEEYVAEIVDESGVLKGRQPWKREVRRDDQLVADRLDHLLHDNVTETQVD
MVKTAH
>A0A2I1NZL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria rhizophila|TrEMBL
MPVTPPTARAEDRPKLVAAPRAADQSAPAPGGHPAAAATPVAPAAGTTSSEPPAGTSWLV
RRPRRSTLVSFEVFPPRPTADPDTVWRSIDAMAQAGPDFFSVTHGHSGGRGVSREALRHL
RRTTRTPVMAHFTCGGTDRAGLERSVEQLLDDGVRDLLALRGDPPLGAGQWRTPPGGIGR
ASELVRLIRDVERRRFGDGFRPGTRPLSVSVACYPSPARGRDPEADLASLWEKQEAGADY
AITQVLYEPEDYASFLERARSEGIHIPVVAGLMPLTNPKRLQRMTEITGVPVPERLTRFL
TADSPEELRHRGTAATLSLIDDLLDLGCAGFHLYTFNRPDAALTILEHLRVRDAAREYRG
RSPAA
>V7FGG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSHC420B00|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILC
GVGPLASAKTARWVRSNVPGIHIPDQIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRRPWKREIRRDDQLVADRLDHILHDDLTETQVDMVK
TAH
>A0A2M8CVJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium CG_4_9_14_3_um_filter_47_13|TrEMBL
MPETQYKTRQEALPTLSFEYFPPKTYEAWETLTTDTAVRLAALHPSFMTVTYGAGGSRRS
WTMETAVAIQKNTAIPTATHLTCINVYKKGLLGIAQTFQDNGIKHIVALRGDVPPEDAPL
DYDDKNYYHYANELIAGLKSIHDFEISVAAYPEKHPEAPDMATDLQNLKRKWKTGADRAI
TQFFFDNNYYYDFLEKVETAGIKLPVIPGVLPIASYERMLRFAAMCHTHVPDKIKERFAP
YFHSQEDMDKVATEILIEQIEGLMQYGVPHIHFYTLNKAEMTLAACKACGLSGKYEQKI
>A0A522MC32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp|TrEMBL
MMTIEISFEFFPPKTPDGVEKLRATRAQLALLKPKFVSVTFGAGGSTQQGTLDTVLDMAK
DGLDAAPHLSCIGSSKDNLREILERYRANGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRAEHGDWFHIEVAGYPEYHPQARSPRHDLENFARKVKAGANAAITQYFYNADAYFRFVD
DARKLGVDVPIAPGIMPITNYSQLMRFSEMCGAEVPRWIAKRLESFGDDKEAIRAFGLDV
VTQLCERLVKEGAPGLHFYTLNAATATKAVCERLGYAGRPA
>E8TGZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium ciceri biovar biserrulae (strain HAMBI 2942 / LMG 23838 / WSM1271)|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A562GP77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa sp. KB1|TrEMBL
MSEAVAIDKQAVLKTDSKLEKLYSLGHFVVTGELGPPQHSEGHELEHHATELKDIVDGFN
LTDNQTAIVRLSSIAAGVHVLKGGGVPIIQMTCRDRNRIAMQSDLLGAYSLGIRDVLCLS
GDHQSFGNHPTCKNVYDVDSVQLIAMVKKMRDEKKLLSDAAIKTNEPRFFIGAVENPFGD
PFEFRAIRLEKKVNAGADFIQTQAIFDIEKFARFMEMVVARGIHERTKITAGILPVRSVK
ALQYMKKDVAGMEIPDSLIERMKKAEDPKKEGIQVSIELCNQLKKIPGVAGIHIMPVGWE
AALPEIVKGAGFLPRPKV
>A0A8H2XAU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKLIEKLANYTSEVPYFTIEFFPPRTDQGYSNLLTRISGLASLKPIAASVTWGAGGSTRD
RSLDLAGFCQADNGLDTILHLTCTNMEKGAIDEALTTAMERGISTVLALRGDPPRGEEYW
IPADPRFRHAEDLVTYIKQHPKFGSHFCIGVAGYPDGHSEGGSEEEQLAHLKRKVDAGAE
FIITQLFYDVEKFKAWLWKVRNTGITVPVIPGVMPLQTYATFIRMTDLCKATVPQHIQAN
LDAIKHDDQLVKEYGVSLAVSMIRSILVDGDIKGVHFCTLNLEKSVRKILDELGWTHVFL
HHNQIITDANQSPRILPAPADALHPVNFTISPSEATQHAATSLAEHTRTGTLRTAAEAID
SGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPPHVAIAQWGRPTTEQELSDLFLAYLSD
KTSTTPFSPEPLSDESATILPYLVSLTKRGLWTVASQPAVDGALSSDPVVGWGPRDGRVF
QKSFVEFFATEEDLEKVAKAIEDSGDGWVTFFAGNNDDGFLTNIPDSGSNAVTWGVFPGQ
EIAQPTNIDRDSFLAWKVRATCIHQNLGLNCD
>A0A8H2WG20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MPPFTRSVTKARLRDVSTPPRTYADRVLTQMQRDSLWDPQAPPRKFSDARGLKDLIEIAV
VFVVATVLDIAKDIVMISKKPIGWVLATYLILMALSGTSDLFVKTFMSPICTLPLISSHI
DYCNRDAFSRRFSPDFPKLASLQSRLEDVMDDSASSSIVAVDIKNSEMAVRDLTTLVKIS
SLVAKDSLVDRLNEFVIDAKAAGRSLQRFGSRVGGAVDQIVTMNEYVLKLLENTAKDSQA
QISSGPVQRVMNAVSPIKTSGPQVIAARRKEVETMWYQATGMMESTIRKLIHEAEVNIIA
LDKLEGQLDLINEMILREDEGIRAKAEEALGELWTKLGGNRKKLNNFRSHRMLLNEIRTY
RKRALAHVSSTLVQLQGLSGDLDDLRQRVATPALVGEEAGIPLEVHIGSMQKGTERLLEG
RKRAREREEAYLQKAPGTDMKVTEKIRQAEKDGRVWWSFEYFPPRTAQGLQNLLDRIERM
RGLGPEFIDITWNAGGRTSDLTSELVKTCQSVIGIETCMHLTCTNMHQEKVDVALREAKA
NGCRNILALRGDPPSGQEEWTSVEGGFQHGIDLVRHIRREHGDYFDIAVAGFPQTIQLPE
AEAKQEMQWLKEKCDAGANFIFTQMFYDGDMFIRWVKAAREAGITIPIVPGINPIQTWNG
FIRATTLSGTDIPQDLMDILEPHKNNDEKVRELGIKIVAELCRKILDADIGIRGLHFYTM
NLEKGTKMLLEELNLVPRVETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWD
EYPNGRFGDSRSPAYGELDGYGIWIKQTPEEGRKIWGTPTTMDDIKDLFAKFCSQQIKAL
PWSDQPPTTEMLIIGQQLARMNELGYLTINSQPAVNGARSDDKAFGWGPKNGYVYQKAYL
EFFVHPTQLQALIKRIERDTNVTYYAINRQGDLKTNSTSEGPTAVTWGVFPGKEVIQPTI
VEAVSFMAWKDEAFELGCQWAKIYEPGSPSRKLIEDMMDEYFLVNFVHNDFHDREAIFRP
FFADAGLKANGDIETLAVNGVKHANGLLNGHSTAVRA
>A0A8H7HFQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKVTEKIQQAEKDGRIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSELVKTCQGVIGIETCMHLTCTNMPQEKVDVALREAKANGCRNILALRGDPPSGQEE
WTTVEGGFQHGIDLVKHIRREHDDYFDIAVAGFPQTIQLPEAEAKQEMQWLKEKCDAGAN
FIFTQMFYDADMFIRWVKAARDAGITVPIVPGINPIQTWNGFIRATTLSGTDIPQDLMDI
LEPHKNNDEKVRELGTKIVSDLCRKILDAGIGIKGLHFYTMNLEKGTKMLLEELNLVPRV
ETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQTPEEGRKIWGTPTTIGDVKALFTKFCTQQIKALPWSDQPPTTEMLVIGQQLA
RMNELGYLTINSQPAVNGARSDDKAFGWGPKNGYVYQKAYLEFFVHPSQLHALIKRIERD
TNVTYYAINKQGDLKTNSTSEGPTAVTWGVFPGKEVIQPTIVEAVSFMAWKDEAFELGCQ
WAKIYEPESPSRKLIENMMDEYFLVNFVHNDFHDREAIFRPFFADAGLQTNGDTETPAVN
GVKHVNGLVNGHSTAVRA
>A0A8H8NR27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKVTEKIQQAEKDGRIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSELVKTCQGVIGIETCMHLTCTNMPQEKVDVALREAKANGCRNILALRGDPPLDKRN
GRPSKGFQHGIDLTIQLPEAEAKQEMQWLKEKCDAGANFIFTQMFYDADMFIRWVKAARD
AGITVPIVPGINPIQTWNGFIRATTLSGTDIPQDLMDILEPHKNNDEKVRELGTKIVSDL
CRKILDAGIGIKGLHFYTMNLEKGTKMLLEELNLVPRVETIKPLPWRQSLTPTRRTETIR
PIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELDGYGIWIKQTPEEGRKIWGTPTP
LVTSRPCSPSLHPTNQSTSVVRPTTNHRNPAVNGARSDDKAFGWGPKNGYVYQKAYLEFF
VHPSQLHALIKRIERDTNVTYYAINKQGDLKTNSTSEGPTAVTWGVFPGKEVIQPTIVEA
VSFMAWKDEAFELGCQWAKIYEPESPSRKLIENMMDEYFLVNFVHNDFHDREAIFRPFFA
DAGLQTNGDTETPAVNGVKHVNGLVNGHSTAVRA
>G2ZAT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria ivanovii (strain ATCC BAA-678 / PAM 55)|TrEMBL
MNLRKDLSEKVLIADGGMGTLLYSYGVDRSFEELNLSHPEDIVSIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLEELKTVLKILRETTDLPVVANVSMHEPGLL
QNGQKLSDALEELIALGADVVGVNCRLGPYHMARALETVPLYEHAYLAVYPNASLPEVQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIKALRNGLKTTKPVLEKEVRPLL
ELVPEEVVDEDSGVRLLDKVKEGLTILVELDPPRTFDTSKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKANINVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMRDAEEQGRANEKGMEIARELIDSICAYFQGIYIITPFLRYDLSI
ELAKYVQTKQQVQVANK
>A0A1I5QQZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus dictyosporus|TrEMBL
MPVEVRGGSRAPSRTHPPTPVHRGPRRRSSAALEQALREASYEVLPLRGTEESVVEHVPP
SVPLTVTVTEAKGLTPTLDLAERLSGHGFTVTPHLAARLVRDAAHLSDVVARLHAADVDS
VFVVGGDAPDPAGESPDALGLLEALETAGHSFRHVGIGGHPEGHGHISTALIERALERKT
PHATHVITQLCFSAPTTTTWARNVALRGVDLPVRIGLPGAVTRQKLVRISAGLGLGQSAR
FLSRQHSLFWRFFLPHGYRPDRLVDGLAHTLGDPEHHLRGFHFSTFNEVARTEAWRQDRL
ARLSDAGTG
>A0A3D5LE94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp|TrEMBL
MRLTELLNKDEVTISCELFPPKQGAQLENYKNIVKDMAALKPAYMSVTYGATGGTSDYTV
KLAEEVRNNNIPALAHLTCASSTREKVASVIEELKAANIENILALRGDIPANADFPLPDQ
YKHASELIADIKAQGDFCIGGACYPEGHPEAATIFEDLDHLKEKVDAGCEFLTTQMFFDN
NILYNFMYKALKKGIDVPIVAGIMPVTNASQIKRITSLSGNMVPPRFLAIVDRFGDNPAA
MRQAGIAYATEQIIDLIANGVNHVHIYTMNKPDVAGEILENLSNIYVR
>A0A2S4M5B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia eburnea|TrEMBL
MAGASRFGLLINTAIMKPIELSFEFFPPKTAEGVEKLRATRAQLLMHKPRFVSVTFGAGG
STQQGTLDTVAEIAKEGVDAAPHLSCIGATRDSLRDILSQYRSHGIRHIVALRGDLPSGM
GEMGELRYASDLVAFIREETGDAFHIEVAGYPEYHPQARSPRHDLEAFAQKVKAGADSAI
TQYFFNADAYFRFVEDAKKLGVDIPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLES
FGDDRESIRAFGLDVVTDLCRRLVDAGAPGLHFYTLNTAGATKAICERLAL
>A0A1I2R9Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium gossipiicola|TrEMBL
MPTASQHRASRDGYRPIRVSIEFFPPKTDEMEQILWKSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETTLKPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPQDGIG
TAYRPHPGGYATTADLVAGIKRIGDFKVSVSAYPEKHPEASSLDADIDALKAKVDAGADQ
AITQFFFENDIYLRYVDKVRAAGIDIPIIPGILPVQNFKQSANFARRTGASVPYWLAARF
EGLENDPDTRRLVAAAVAAEQVLDLVDRGIEDFHFYSMNRSDLVYAICHLLGLRSQAPKV
ETAKAA
>A0A1B9MQJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVQPKDDF
RFASELVTFIKENSDFNVIGACYPEGHLEAATLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYTFLDKARDIGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEYHPEAF
RDAGIAYAIDQIVDLVSQDVDGIHLYTMNNSYIARRISEAVSTLLVVPKSE
>A0A3E4FZM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. D20|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>C7CDH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum extorquens (strain DSM 6343 / CIP 106787 / DM4)|TrEMBL
MPNASQHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVDATKEEIDGVVQSYWDAGVRHIVALRGDPAEGVG
HSYRPHPGGYAQTCDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIEALKAKVDAGADQ
AITQFFFDNEIYLRYRDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLENDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
PAVKPEAKAA
>A0A127MGN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingorhabdus sp. M41|TrEMBL
MNNPARPKGLIELEEAKRALDVPLFAGLSGDADVSFEFFPPKSEKMEQTLWDSVVTLEPL
NPRFVSVTYGAGGTTRERTHATVARIAKETNIPAAAHLTCVGASKAEIAEVARSYWDAGV
RHIVALRGDPPAEGQAFEPHPQGYASAAELVKGLTDIAPFEISVAAYPETHPEASCPQSD
LDNLKRKLDAGASRAITQFFFTAEAFFRFRDAAAAAGIDAELVPGILPVSNVAQTRKFAG
MCGAEIPPWMNDLFEGLDDHPSARQLIAATVAAELCRKLYAGGVRQFHFYTLNRAELSYA
ICHLLGKRPTGERQEKAA
>A0A0Q8A0J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root151|TrEMBL
MRNKLDVGGKTRNQTMRRLLEQARYEVLPTESTEQKVVENVPLDRMITVTASPSKGLGAT
FDLAERLTGHGYAVVPHLAARMVSGRGELAEICDRLTSGGITRVFVPGGDAEPAGDYPDA
LSLLEDLVALGRPFAHVGITGYPESHPQISDDMTVQAMWDKRRHATHIVSNLTFDPAVIK
VWLERMRKRGITMPLLLGMPGPVDRTKLLGMATRIGVGESTRFLAKHKGTFARLAAPGGF
TGERFLARCAPALGAPTAFVEGLHVFTFNQIAETEAWRTDLLQRL
>A0A836ZJ31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. syringae FF5|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGE
>A0A1U8HWP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium hirsutum|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
RKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DALVKNCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGAFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSTLYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0RIN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis (strain Al Hakam)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEALKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A5M3X0S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acrocarpospora macrocephala|TrEMBL
MSGGLRAALASDRFVVTAEIGPPRDADPDAIARKAAALRGWVDAANVTDNQGASVRMSSL
AGSVLVQRAGVDPVMQLTCRDRNRIALQSDLIGAAALGIRNVLLLTGDHPTLGDHPDAKP
VFDLDGVQLVWTARTLRDDGTLLSGKPLATRPSWLIGTVENPFAPPAALRARRLAKKVAA
GAEFVQTQYVFDVAAFAGWVARLREEGVTERCAVIAGVGPIRSLRMLAFLTGSVPGVHVP
AELERRLRGVPEHRVAEEGLNACVETIQALVEIPGVRGVHLMVFGHDDEVPDIVRRAGIR
PAVAALQEGRQ
>A0A7Y5D6S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp|TrEMBL
MTAISFEFYPPKTDEQRALLDRTAQKLKSYAPDYVSCTFGAGGSTLSYTSETVRHLKQEH
GFDAAPHVSCMGGSREEIRELLRLYRALGCKRIVALRGDLPSGMGHHGDLRYASDLITFI
RDEHGDHFHIEVGAYPETHPQAEDALADLRHFKTKIDAGANGAITQYFYNPDAYFRFVDD
VRKLGVTVPVVPGVMPISNFTQLKRFSESCGAEIPRWMGKRMQALGDDADGVREFAADLV
ATMCKRLIDGGAPSLHFYTLNLAKPTQAVLARM
>A0A7C0YIU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MSESKTPSKLEKILSSGHLAVTSECGPPRGSDPETIRKKAEMIKDHVDAINITDNQTSVT
RLCSLASCIHLKHMGLEPVLQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQKFGDN
PQAQNVFDIDSMQLIQMVRLMRDEGKFLGGDDIVRPPKMFVGAAANPFADPFEIRVPRLA
KKVAAGAEFIQTQCIYNVERFKEWMRGVVDRGLHEKVYILAGVTPFKSAGMAKYMKNRVP
GMDVPDELVKRMSGVPKEKQPEEGLKICVETIQQLKEVEGVSGFHIMAIEWEEKVPEIVE
ASGLYPRPKVDD
>A0A2N5H3H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. T33-2|TrEMBL
MSFLQKLQDEILIADGAIGTLLYSYGTGSCFEELNLSHPEDIVSIHQAYLEAGADVIQTN
TYAANYIKLQRYGLEDHVKEINSAAVRIAKQAAENRAYVMGTIGGNRGIKPNTIPLEEIK
RSFREQLYCLLLEGVDGIILETFYDLHEVETVLAIARQETALPIIAQVSLQEPGIMQDQT
HVNDALKRLAGLGADVVGVNCRLGPHHMLKTLEEVELPTNAFLSAYPNAGLPAYTDGKYH
YKGESEYFRKSAHAFIEQGIRLLGGCCGTTPEHIRALADEVKRDVPITEKTVKKKSVEIT
AQLIPAKRDDPPLHSLVNERPSVIVELDPPRKLDTTRFFEGAAALKDVGIDAITMADNSL
ATPRISNTALGHLVKTRIGIRPLVHITCRDRNIIGLQSHLMGLHTLGLNDILAVTGDPAR
VGDFPGASSVYDLSSFELIEMIRQFNSGLSVSGKDLGQKGNFSIGAAFNPNVRSIEKAVL
RMEKKIAHGADYFISQPVFSEETLLQVYESTRHIKAPLYIGLMPLTSSKNAEFLHNEVPG
IKITEDIRDRMASLSDDPVRSAREGIAITKTLIEAASELFNGIYLITPFMRYEMTVELAQ
YAQEYSARLSRRKLHNAERAIN
>K9NRA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. UW4|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A2G9HLS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Handroanthus impetiginosus|TrEMBL
MKVIEKIQEATAANANRVVFSFEFFPPKTEDGVDNLFERMERMVAHNPAFCDITWGAGGS
TADLTLEISNRMQNMVCVETMMHLTCTNMPVEKIDHALATIKSDGIQNVLALRGDPPHGQ
DKFVQVEGGFACGLDLVKHIRSKYGDYFGITVAGYPEGHPDVIQDGEAPLEAYQNELAYL
KRKVDAGGDLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPPEIMAALDPIKDNEEAVRAYGIHLGTEMCKKILASGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVSRVKEDVRPIFWANRPKSYISRTICWDQYPRGRWGDSRN
ASYGALSDYQFMRPRSRDKKLKEEWAVPLKNVEDIYEKFMNFCLGKLRSSLWSELDGLQP
ETKIINEQLGNINLKGFLTINSQPAVNGVQSDSPSVGWGGPGGYVYQKAYLEFFCSLEKL
NVLVDKCKLFPFLTYMAVNKEGSWISNVNKTDVNAVTWGVFPAKEIIQPTVVDPASFIVW
KDEAFEIWSRGWAKLYPEADPSRKLLEEVQSSYYLVSLVDNDYVHGDLFAVFRDI
>A0A094P2Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|actinobacterium acMicro-4|TrEMBL
MAQSTDTVAVSFEVYPPRSAEKMPDLQESIRVLDSVSPDFISVTFGAGGSSTRDSLEVLR
FIRDESSATPLAHLTCVGTTRQEASELVVSFLAEGITHFLALRGDLPEGALEHHGELHYA
VDLVTLMRELPGAPKPLERIAVAAFPNGHPESHSLDHDVETLLRKQEAGATLAITQLFFY
TEHYLTFVEKAHGAGVTIPILPGLMPVVSPGRLNRVVELSGENRPSELSEALSSTEDAAA
REAIGVDWTAHMVRELVDAGAPGIHLYAFNQHRTVLSVLEQSGVRQCIQ
>A0A4R8EQB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrotoga sibirica|TrEMBL
MKIIDLIKQSIKPILSFEIIPPNVGESIDPIFNVVDNLIDFSPKFINVTKHANEIEYVEE
NGEIIKIIKKKRPGTVGVSASIKHRYDIEVVPHLICTGFNKYQIEDILIDLNYLRIENIF
VVRGDKKRYTWKETDEYEHATQLVEQVTNMNKGIYTCPTKEHNPTNFCIGVAGYPEKHFE
SPNLEKDLDYLKLKVDIGAEFIITQMFFDIEYYKNFVNKVRELGIEVPIIPGIKPLGSKK
TLYNIPKTFHVNIPKTIVEEFEDAKSFQDEYIIGVRHGIKLIEQLLELRVPGIHLFTMGK
GKIVKDILSAFKGIF
>A0A0M8VMN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MMG1121|TrEMBL
MRDVLDRTTPSFSFEFFPPKTDAGARTLWQAIRRIEALAPTFVSVTYGAGGSSRDRTVEV
TKRIAAETTLRPVAHLTAVGHSAAELRHIIGQYADVGVRDVLALRGDPPGDPNAPWIAHP
DGFTHARELVRLVRESGDFSVGVAAFPERHPRSPDWESDIRHFVAKCRAGADYAITQMFF
QVEDYLRLRDRVAAAGCDTPVIPEIMPATDVRQIARFAELSGAAFPEELAHRLEAARDNP
ADGHRIGVEYATAMAERLLAEGAPGLHYITLNRSTATLEIHRNVLNSRSNQHVLAAQR
>A0A3M8GQK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda sp|TrEMBL
MKVTDHIKKAKGEPLFSFEIIPPIKGKNIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGSLGICAAIKHKYDVDAIPHVLCGGFTKEETEYLLVDCHYLGIDNI
MALRGDAMREEKYFEPTKGGHHYASDLVKQIQELNKGNYLHEVIETDNCANFCVGVAGYP
EKHMEAPSLNSDLKRLKEKIDLGADYVVTQMFFDNKKFFEFVEAARDMGIDVPIIPGIKP
IAVKRHLQLLPQVFRVDIPEDLVDAVEKCKSNKEVRQVGIEWCIQQSKELKDAGVPVLHY
YSMGKSDNIKAIAEAVF
>A0A1T5ALS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malaciobacter marinus|TrEMBL
MFETLIQKLQEDKYLTLETTPQHEPIMHNIIEKVKKFDLQNRVDGFSATDNPLAKLKYNA
LFASLRLQQEFKKPVIATMSMRDRNKIALQSDLLGANEFDVRAILALTGDPAKMSDQPHS
KGVFESNSSMLLKMIKSFNYGMDIAGRPFKIEPKQIYPFAVTNSYARSFTSLEKKMHNKI
QNGAMGIITQPVFDVNNAKKLLEIFENAKEDVVGNKKKAQLIFGIFPITKLRTALFLSAQ
VPGIHVPQDWIDKLELANQISEEEEYKVGMQLSKDLFYEIRKLHPKIHLMTANKFDLADE
ILA
>A0A0F8UUL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus ochraceoroseus|TrEMBL
MAQALRPLFVTVTWGAGGSTASRSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEA
KVLGIRNILALRGDPPRSEEYNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCVGVAAYPE
GHPADSFQEVQDPEVDLPWLVEKTQAGADFIMTQLTYDIDAYTRFETMLRNHESGAFKTI
PIIPGLMPIHSHKILTRVTKLSHVKIPPPILAKLEEVRYDDDAVKRIGVDIIAEIVDGVR
KLVCPGLRGFHFYTLNLEKTVSFIIERCNLIPDYPEDSEAVDVSEELSALTVDGSQASTL
ARRRRASSVGSIPHNRVIVDRVTETSSKGSVTHETPAASAGMPALPPDRNTTLQISEGLG
ALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVAPAVAHRIWGYPVTYDDISNLFRR
HVSGDLYMVPWSEGGAEENSSGLNAETETIRPELLQLIDNKGWWTLASQPAVNGVRSDDP
IYGWGPPGEGFVFQKPFVEFFCPTKDFQTVLKPVLKQHGHEKLAWFAANSKGEFETSLPA
QSAEADPIEMNPANVNAVTWGVFRGKEIITPTIIEEVSFRAWGDEAYRIWDEWRRIYPRN
SPTERFLDKTRDDVWLVCVVGQDFGAGTEIGSQEEQDEKKWMWNVLANC
>A0A840HUJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizorhapis suberifaciens|TrEMBL
MTFTLTQLEEARRALDAPMFGDLSGDAHVSFEFFPPKNQKMEETLWSSIQTLAPLQPRFV
SVTYGAGGSTRERTHATVARIVRETDLLPAAHLTCVDASKAEIAEVAQAYWEAGVRHIVA
LRGDPPEEGKGFSPHPEGYASAADLVAGLKEIAPFDLSVAAYPETHPEAVSSQADLDNLK
RKLDAGASRAITQFFFSPETFFRFRDKVAAAGIKTEIVPGILPVSNVAQTRKFAAMCGAA
IPPWMDRLFEGLDDHPSTRQLVAATISAELCRKLYAGGVREFHFYTLNRAELSYAICHLL
GLRGRPEAQLREEAA
>A0A832HMI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHIADIFARDKTTFSFEFFPPKTDAAAETLFAQITELETLKPSFVSVTYGAGGSTRERTH
NIVVRLKDTTSLDPVPHLTCVCHTQEDIAKIIERYAQHGVSNILALGGDPPRDLANYVRA
NDAFQHAANLVTFIKNFAGHPDKRGFGIGVAGFPEGHPSTPNRALEMDYLKAKVEAGADY
IVTQLFFDNRDFYDFRERCEIAGIKVPIIAGLMPVTSLPTYKRIPELALGARYPAKLQRS
IMRCGDDVEAVKRVGIHWATEQARDLLDHQVRGIHFYTLNTSHATREIYRSLGVKDSRAL
AG
>A0A8G2IR63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae|TrEMBL
MAMSQAIHLRDQSDVLDDFSVEVTTKDTTQLAAMSGAIPKGTIISIPFLSAESDADRIRA
AKMVRQAGYVPLPHIAARRLGTESMLSAMLSALVNDAQVSRLLLVAGDADPPKGPFLDTA
TILRSGILEQHGIRHVSIAGHPEGHPVQNAAMLTSALLEKRLIMEAANIEWSIFTQFAFA
SEPVLAWIGELRRLGIEVPIHIGIPGPASVRTLLKFAAVCGVSASTAVLKKYGLSITQLL
SSAGPDALVNEYATGLSNAEYGDVRLHFYPFGGLHKTVDWLQEYRTRPS
>A0A7C8HG58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Defluviitalea raffinosedens|TrEMBL
MKLSQIYSSDTRRLSFEIFPPKTDIPIDTVFDTISKLKQLNPSFISVTYGAGGSNKGRTV
EIASKIKNEHGLEAMAHLTCAGHTKEDIDYILEELKQKGIENILALRGDPPTNQPNFDYH
KNDFPYAVKLIEYIKSKGDFSIAAAAYPEGHKDSKSITKDWYYLKEKVDAGVDVLITQLF
FDNRIFYHFMEDIERIGIRCPVIPGIMPIFNSKQIKRIISLCGSSMPGELLTMMDQYGDS
QDDLRKAGIEYAIRQIQDLLDNGVLGIHLEPMNRPALAEEIIKGLSYKFN
>A0A8I1PL91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp|TrEMBL
MSLREAFDAGRFAVTAEIGPPRGADPEAITRKAELLRGWVDAANVTDNQGAHVRMSSLAG
SVLAMRAGVEPVMQLTCRDRNRIALQSDLISAGAVGIPNVLLLSGDHPRFGDHPDAAPVF
DLDSTQLVRTARTLRDEGVLASGREIGTRPGWLVGAVENPFAPPRSFRARRLAKKVAAGA
EFAQTQYVFDVEVFAAWMARLRDLGVTEGCKVLAGVGPIRSLRVMEFLRSGVPGIHVPDE
VERRLRGVPADRVADEGVTMCVETIQRVAAIPGVAGVHVMAFGYERGVPGILERAGITPR
PAVSMEGLGHAG
>E0UG17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gloeothece verrucosa (strain PCC 7822)|TrEMBL
MINNFRQAVKEKNFLITAEVCPPKGGNPARMLKMAECLKGRVHAVNITDGSRAVLRMSSL
AASVILLKNGIEPICQMACRDRNAIGLQADLMGAYALGIRNILALTGDPMKAGDHKKGRS
VFELESVRLLKVIDKLNQGFDLNNQPLPDEALDLFPGAAVDPQSESWSGLKTRFERKLAA
GAQFFQSQLITDFDRLDKFMHQIASATDKPVLAGIFLLKSAKNAIFIKRNVPGVHIPDEI
IKRLGEASDPLLEGVKIAAEQVKMAQQLCHGVHLMAIKREDLIPQILEQAGIAPIE
>A0A838GLW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporichthyaceae bacterium|TrEMBL
MQARVLVASLRRPRYEILAVPGAVDEVSEHVPPEITVTVTTSPRRPIETTIETVEELARA
GYPAVPHLAARQVVDQMHLVDLLDRLRSAGVTEVFVIAGDGDPVGTYSDSVALLAAMAEL
DHGLSRIGVGGYPEGHPKIDDVALGQALRAKAQHASYAVTQMCFDPGAVSAWVLRIRKDG
IGLPVYVGLAGVVDRRRLLRIATRIGVGQSAHFLRRHRGSALRLAVPGAYRPDRLISALA
DDLGRPGRGVVGLHLYTLGNVAATERWRRQMLQRLGVAERLQ
>A0A7Y5S3A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MRIRELLYGGRPCISFEFFPPKDEAGFEPLREALASLRELRPTYVSVTYGAGGGTRRRTV
ELVTQIRRDYGIEAMAHLTCLGASRDEIGEVLDTLSAAGVENVLALRGDPPRGQERFEPH
PQGFRYASELAAFARQRHRFCLAGACYPEVHPEAPDAATDLANLKRKVEAGCEFLITQLF
FDNQCYWDFVARARGAGIGVPILPGIMPITNVAQVERFTQMCGATLPASLLAELRRLEDD
PHAVLSLGVAHATAQCLELLQRGAPGIHFYTLNKSPATRTILMALQNVYPPARTPAGA
>A0A2P7ANK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium endophyticum|TrEMBL
MSFFRQSRRSDLGTNIRVSFEFFPPKTELMEERLWETVTRLAPLNPDFVSVTYGAGGSTR
ERTARTIKRILTETDVNAAAHLTCVDATKEEVDAIVREFAAMGVKRFVALRGDPAGGVGA
HYKPTPGGYENGAELVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVEKVRRAGIYIPILPGILPIHNFAQVTNFCSKAGTHIPAWLAERFD
GLENDPQTHALVSSAVAAEQVLDLVERGIQDFHFYTMNRADLPFAICHLIGIRPASGNAV
EVNLAGAAA
>A0A395LHH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteriqipengyuania lutimaris|TrEMBL
MTAQSTPALDPREEQARAKKDPLFSGLPGDIDVSFEFFPPKNEKMEKSLWDAVQELKPLD
PHFVSVTYGAGGSTRERTHKTVERIIAEAGLPAAAHLTCVNASRRETQKIAEKYWEAGVR
HIVALRGDMPQEDGSLGPFKPHPDGYNSAEELVHGLKEVADFEISVSAYPEMHPDAKSQQ
DEIDYLKRKIDAGADRAITQFFFSPNTFFDYLEKTDKAGIDVPIVPGVLPITNVSKARQF
AGQNGAEFPDWMEGVFEGLDDRPSARKLVAATVAAEMCRRLYAGGIRHYHFYTLNRADLA
YSICHLLGMRPQDGAGAKEKAA
>A0A2H6FM03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Abin08|TrEMBL
MSFREALESGKFVVTAEVGPPKGTDIEEMIHHIELLKGKVDAINFTDNQSAVMRMNSLAG
CKIALEHGVEPILQMTCRDRNRIGLQSDLLGAYALGVRNLLCMTGDHVSAGDHKGAKPVY
DVESVQLLQIVDSLNNGTDMSGNDLKGKCDFFQGAVVTPEANPLEPQLIKFEKKVRAGAR
FFQTQAVYDIEKFKEFMQYAGKFSVKVMAGLVVLKGAGMAKFLNNYVPGIVVPQELIDEL
KEAGKEKALDTGLSICARHIRQLKEEGICDGVHIMAIGMEDRVPDIMERAGLL
>A0A695HQT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITHILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYDNNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELRA
>A0A5E8XSR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.042.01.1.1|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAQRLDHILHDEITETQVDMVK
TAH
>A0A1X1DCY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea wallisii|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWSSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATREELRGIARDYWESGIRHIVALRGD
LPPGSGKPEMYGADLVALLKEVGEFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPGWMSAMFA
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPPAAA
>D4K157|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii L2-6|TrEMBL
MTDIREYLAHKPLLFDGGMGTYYKAAPGADCEMANLTDPEGVKKVHAEYLAAGAQAIKTN
TFGLPRMAAAQTPGWEELAEAGWKLACDAAAEKDAAVFADLGPAPDTEAAPASSAYGLVA
QQFAALGAKNFLFETLSSDVGIVEAVKALRVAVPDAFVMVSFAVLPDGYTREGLLFRDLL
RRMEQSGVVDAVGLNCVSAPGAMKKLVQGLGETLLPLSVMPNAGYPVVTRARVLYQGKPA
YFAREMGQIAAAGVRILGGCCGTTPAHIAALRAELDALPQRTEAAPAAKLSTGTAPAVEK
DDAFLRKLNAGEKVIAIELDSPRVADLSGYLDGARRLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGMCALPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSAMTVLGALNLNARNFDVELRRAVEKLENGMSGFL
TQPVLSAQAVENLRKARQTLGERAKILAGIMPVVSQRNAIFMENEINGIHVEEDIIQRFA
GLDREQGEALGLEVSMQMAREALPYADGFYLMTPFNRVALMERLIARLKTELLDAED
>A0A8C7NY27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
MFEDTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRHRTESGDHWFS
LEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYATDLVKH
IRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVR
DCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGIEQ
AVSMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHPKRKVED
VRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMW
GEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVNRRGVLT
INSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIV
NVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQWAKLYED
ESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEQPAEQPND
EQSDKEQPGK
>A0A8C3AEX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclopterus lumpus|TrEMBL
MVNQVQRGDGSLRSCKSDSSGLSNSGGESSKESSRCSTPVLEADRSDRLRDKMRRRTESG
DRWFSLEFFPPRTASGAVNLISRFDRMSAGGPLFIDITWHPAGDPGSDKETSSMMIASTA
INYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEEGFNYAT
DLVKHIRSEFEDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITRVIEPIKDNDAAIRN
YGVQQAVEMCRVLLDSGKVPGLHFYTLNREVAIMEVLRQLGLWIEDPRRSLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSTKDA
LLQMWGAELMNEESVYEVFTCYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNK
RGVLTINSQPNINGKPSADPIAGWGPAGGYVFQKAYLEFFTSSENVTALLEVLKKYEPRV
NYHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWQVIDDMFKMLDAPPGREMLCMMT
M
>A0A854EYZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. MB339|TrEMBL
MSAPTSLRVQAFLDAFSLEVSARAMPALGAEATRIPRGTTISIPWLASEDDDARLAAARR
VRELGFEPMPHLSARRIGSRAVLERFLQRAANEAGVAQCLVIAGDLATPAGPFADSASII
ESGLLERAGIKVVAIGGHPDGHPVLGSDACWQVLEHKCQSIEARGMAPVIITQFAFDADI
VLAWLHALRARGIHVPVLVGVPGPASIARLVRYAAMCGVGASALMLSRYGISIGRLLGSA
GPEVFVDRLAGGLTDAHGLVSPHFFPFGGIAQSLDWINQHRALPSVARR
>A0A8C7VRM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
MPASFAPSTSVWDLGLVRDNQCLSNSSGTSNSGGESSKESSRSSTPVLAADRTERLRDKM
RRRTESGDHWFSLEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSNKETSS
MMIASTAVNYCGLESILHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEE
GGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQL
FFRADTFLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKD
NDAAIRNYGIEQTVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPW
AVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLK
SKSSKDALLKMWGEELTSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDELLAPETNLMMD
ELDKVNRRGVLTINSQPTINGKPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVL
KKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFA
LWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEE
QPTEQPVEQPAEESPVEDQSPK
>A0A8C7NYA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
MVNLVQRVEDTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRHRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIR
NYGIEQAVSMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVN
RRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEAL
RQDCVDAQIW
>A0A3C1LWX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKINEIARNKKVTFSYEIFPPKPNSPVLSVYESLDKLSAQRPDFISVTYGAGGSLVSNKT
LVLSSYIQDRYNIPSMAHLTCINSSKQYILAVLEQLKANGVYNVLALRGDKTPDITPAGD
FNYASELIEFIKNNSPEICISAACYPEGHIDGGFEKDIQVMKDKYSCGAEHFISQLFFDN
SHFYRLMDRAAQLNINANIEAGIMPVLNKNQIERMVSMCGCSFPEKFRKMVERYQDDKSA
LLQAGINFATEQITDLLSNDVKGIHLYTMNRPEVSEKINENVRYLVDYLNA
>A0A4S8V5Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEVTAPEAPQ
KVNGATNGEKHEEEPKVGNGDITDSKIPDSVHKKLETQINVAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A3N5IGG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MSREPRRLREVLDQGQFAVTIEYNPPKGTNISGVLENAKQLVGRVHGVNVTDNTAAVVRA
GSLSVCRLLYELGHDPVMQMTCRDRNRIGIQSDLMGASMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGRDMAGNKLDGSTAFMIGAAVTPEADPLGPMLAKFEVKV
KAGAQFFQTQAIYHPEQFASFMSVVRPFKAKVLAGILVLRNAKMAEFMNANIPGVSVPQE
MIDELRAAGSEHAEDVGVDIAVRTIKAVRPHCDGVHIMAIKATHRLAEIITKAEVG
>A0A4S9WXE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVNVTWGAGG
STSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDGALEQAKALGIRNILALRGDPPRS
DEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQSHPEHQHA
TYDVPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGLMPIQSYQ
ILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSGPKGFHFY
TLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSIANSAPQNRVV
IDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIPWSEEGLN
PETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVEFFCSHED
WTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIEAVSFRAW
AEEAFGIWTEWRHVYPPRSPSAKLLREIRDDYWLVNIIHHDFTENNGLWKMLLEA
>A0A1R3VHR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium prunaredense|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A0F3H0T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Magnetobacterium bavaricum|TrEMBL
MHKKVVGGFVKREGEQIMSFKETLQSGKFVVTAEVGPPKGTDIATMLHDMHLLKGKLDAV
NVTDNQSAVMRINSMAVCKLAIENGLEPILQMTCRDRNRIALQSDLLGASVLGIHNVLIM
TGDHVSAGDQKGAKPVYDIESVQLLQVVDGLNNGKDMYGNALKGATSFFQGAVVTPESNP
IEPQLMKFRKKVKAGAHFFQSQAIYDIDKFKEFMAFARQFPVKVLAGLVVLKSVGMANFL
NNNVPGIKVPQVLIDELKAAGKEKALDTGLNITARHIRQLKEENICDGVHIMAIGMEDKV
PTILQRAGLL
>A0A4V4JYS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLDKEIAAPEAPQ
KVNGATNGEKNEEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A354CRP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKTTELFKTKTTLSFEVFPPKPTSDESVIYKALDGMSLLKPDFISVTYGAGGGANCKKSV
QIASDIKHKYRIESVAHLPCVALSEENASSVLEQLQAAGIENILALRGDITPEIVPDGRF
KHADELISFIAEKYDFNIIAACYPEGHVESGSLDEDIAYLKHKVDCGASQLITQLFLDNR
FFLDFRERTGKAGINVPIEAGIMPVTNRAQIERMVKLCGVQLPKKFLKAIEKYEHNPAAL
RDAGIAYAVDQIVGLLAENVDGVHLYTMNNSYVAGRICESVKSLFEV
>A0A3C1G6S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MGAAFTPGGEPLDFRPFRLKKKVDAGADFIQTQGIYDLEMFKAQM
>A0A143YMP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus ilyis|TrEMBL
MKIESKFQKKKPVLSFEIYPPKRDKAIQNIDETLAILSELNPDFISVTFGAGGSHTNNQT
VALAKRIKHQFGIDPLVHLTCLNSSKFEICELLEELKDADIDSILALRGDVNPEVEAKKD
FRYASDLVKFIRQYGDFSISGACYPECHTESKNKVEDIAHLKEKVDSGVQHLISQLFFDN
NAFYSFQEHIQIAGMQVPVEAGIMPVINKAQIEKMVTLCGASLPEKFSRIMHKYEDNKEA
LFDAGMAYAINQIVDLLAHDVDGIHIYTMNNPIVAKRICDGIKNLI
>A0A4S9B5L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQSAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEVTAPEAPQ
KVNGATNGEKHQEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A319CLV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus vadensis (strain CBS 113365 / IMI 142717 / IBT 24658)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDVQDPARDLPYL
IEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPQVLSKLEEVKHDDDAVKRIGVDIITDLVYGIRDLVSPGLRGFHFYTLNLEKT
VSFILERCELIPPYTEIDDSDALVDGGNLSAMDSSSYIAPNGAPIRTLASRRSSVSSIPH
NRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEEDSNGLNAETAVIQPELLTLIDKKGWWTLASQPALNGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPNKDYLNVLKPLLQKHGHEKLAWFATNVKGDFECSLPGPNPDDPDPIDIN
PANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDETK
NDVWLVCVVGQEFGAGTEAGSEEEEDEKKWMWRELANSQ
>A0A1V4PB40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. LEMMY01|TrEMBL
MGLLDELKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPLIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPERAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIEAMAKALSDRTPVTEKTVKRRAVSVS
VQAERPAPSPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKERLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVYEATKHLDTPIYIGIMPLVSARNAEFLHHEVPGIT
LSDEIRARMAACGDDPVQAAREGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A8C9T5Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scleropages formosus|TrEMBL
MVNQVQRMDGGSQAPKSDSSGASNSGGESSKESSRCSTPLLDADRADRLREKMKRRIESG
DRWFSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKDQITAHLAKAKRLGLKNIMALRGDPLADVWEEEECGFNYAT
DLVKHIRWEFGDYFDICVAGYPTGHPEAESYEADLKYLKEKVDAGADFVITQLFFRAETF
LKFVKDCRAVGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEAMMQVIEPIKDNDAAIRN
YGIQQAVDMCKVLLQSGDVPGLHFYTLNREVATMEVLKQLGLWNEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LVKMWGEELMSEESVFEVFTNYITTQPNRNGHKVMCLPWNDDPLAPETNLLKGELEKVNR
RGVLTINSQPNINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVQGKNITNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKVGSHFSPGLESR
TALGFISRTLGVFE
>A0A8E2WYB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinokineospora spheciospongiae|TrEMBL
MTTVTERLRTDRPVFSVEFMPPRDEADERRLWKAVRELEGLDPAFVSVTYGAGGSSRDRT
IRTTGRMATETTLVPMAHLTAVDHTVAELRNVIGWYAAHGIRNVLALRGDPPGDPNGPWV
STPGGLNYADELVALVRELGDFCVGVAAFPYGHPGCTDLDADTDNLMRKFAAGADFAIAQ
LFFQPEDFLRLRDRVAARGTDKIVVPGIMPLTTPKMLYKTVELSGAPLPPHFAARLEPLA
EDAKAFRAEGIDLITETCQRLLAEGVNDLHFYTFNQSKATREVVGRLGLVPTRA
>A0A7U8SVU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus C160|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A5B8L5C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor sp. SY7|TrEMBL
MSGQRPHQVDENPAGVDLPLDALPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYE
RAAIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPILQISCRDRNRIAIQGDVLG
ASAMGVGNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRTMRDEAKFLSGRKLTTPPA
VFLGAAINPFAPPHEFRPHRLAKKVAAGAQFVQSQYCYDVPLFREYMKKVRDLGLLDKVF
VMCGVGPLASARTARWMRSNVPGVHIPDAIIERLEGAAEQKKEGKRICIDIINEVKEIEG
VSGIHVMAYRQEEFVAEIVHESGVLKGRKPWKREARIDDAMVAERLDHILHDETTETPQQ
IVKEAAN
>A0A5R8N8Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea sp. KC401|TrEMBL
MALGRHSFFPERVPTVRDMLAGGGRSFSFEFFPPKTDEGERLLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERVARATTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVR
GDPPGDPTAEWVPHPEGVHYAEDLVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTDYFVR
KCRAGADYAITQMFFEADDYLRLRDRVAAKGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPRLAARFEAVKDDPAAVRRLGIEHGAELCQRLLEEGAPGIHFITFNRSSATREVFQRLS
GMRLSA
>H5X8H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora marina XMU15|TrEMBL
MTTQQEVAGPRRRRSQLAELVRNISYEVMPFKNTEQAVLSHVPTEVPLTVTVTEAKGIDT
TLGLTEKLLRHGYQVAPHLPARQFTGESHVAEVVDRLRAAGTRSVFVVGGDAPEPAGPYP
DAYSLLQAMEAARHPFEHVGIGGYPEGHAIIPDESVELALKQKAPMATRILTQICFDANT
TASWAGRIAAAGIDLPVHVGIPGPVNRQKLVRISAGIGLGQSARFLRKQQNLLWRFLLPG
GYNPTRLAKRLAASAPKSGGNIRGLHIFTFNELRGTERWRQQLLASLSGKEDRS
>A0A1I2CWB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces mirabilis|TrEMBL
MLATGKATYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSVTYGAGGSTRAGTVKETEQ
IVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVPHPRGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDVDVAHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVVAAGCTTPVIPEVMPVTSVKMLERLPKLSNASFPDVLKERILTAKDDPAAV
RSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGLHHPQQA
>A0A1A0KQC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. 1100029.7|TrEMBL
MTSTELDCPKRMEFGPCGGVRPDGQCEMRPGACVFVDVVPWSGVTRAPSAVRAPLVLADF
SCTPFDRNDVAATAAVLAPGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDR
NRVVLEQELRGLRSIGLETVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGMVPAV
PETPTAPPVHARPQRLVQKQRAGASLAVLNHVPFPKMVDEFMAAATAAGLSIPVIAAVAV
FTDSVSAAVLQGLPGLQLDDSVTEHVLGAADPVAAGIAAAVEEARALLSIDGVAGVNVSG
LASASGGRVGAEIKAEVGRLIRGEAS
>A0A1Y2UTQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypoxylon sp. CO27-5|TrEMBL
MEKITDKIAALPVDSSYVSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
ATKSLELAEICQRELNLTTCLHLTCTNMSRKLIDRALEDAKALGIRNILALRGDPPRAAE
YQGPNENPEDAIDETFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHADESHPLGQSLEHDL
PYLVDKTLAGADFLMTQLFFDTEAYGKFERTLREHPSGAFKTIPIIPGLMPIQSYQMIKR
TTKLSHAKIPDAIMSRLDAVKKDDEKVKSVGVDILCEIVEQVKQITSRTPGPTGFHFYTL
NLEKAVSFIIERTNLIPPTTPIEDEAVVEDIASKIPTLQINGSDHEHDHAPKTSRENSRT
RRQSNVSSEHRNRVIISGRPVSHPEYEATSAEASIPAEPINSRSNTLAISEGEGVLGREA
TWDDFPNGRWGDARSPAYGEIDGYGPSLHVSHAQAVSLWGYPTKREDINELFVRHLKGEL
TAIPWSEEELNEETRTITDKLVRLNSKGWWTVASQPAVNGLRSSDPIFGWGPQNGFVFQK
AFVEFFIPSTEWKILLEKLQSSEVQDTVCFYAANAAGDFVSSDLTGGLAGERKESSTNAV
TWGVFPGKEIITPTIIEEVSFRAWSEEAFGIFGEWAQVYGKGSESEKLLDKARADSWLVN
IIHHDYVDKDALWNLLLD
>A0A1H1AH06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter chromiiresistens|TrEMBL
MNSFLLPARAATRARFSFEVFPARSGAAALALGHAVQHLSAADPDFISVTYGANGSNRDA
SLDLVAYLRDHTDALPLAHLTTVGETPDAVRAAIHAIMDAGVHDFLALRGDPPRGLDERD
ARVAGSMSSWELVRLISQARAERPPLTSVGRTAVAAYPNGHPLSRSRAEDVDWLVAKQEA
GANLAITQLFFRAEEYLSFVEDARAAGLTIPVLPGLMPVSTSAQLRKVASLAGRPAPVEL
ARALDAEGGYAPELGVEHTVSLARELLDGGAPSVHLYTFNRHEQVLAVLRELGLLTPDPV
>A0A2P8E4C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloactinopolyspora alba|TrEMBL
MSTVVERLNERRPVFSVEFFPPRDDDTDEAALWKAVRQLEPLDPAFVSVTYGAGGSSRGR
TIRTTKRIADETTLAPVAHLTGVGHSKAELRNVVGWYAENGIRNVLVIRGDPPGDPAGEW
VPHPEGIMYADEMVEMVSACGEFTIGVAAFPHGHPRSPDLETDTEHLVGKIRAGAHFAVA
QLFFEPEYFLRLRDRLAARGCDVPMLPGVMPLTTKKTLAKSIELSGVDAPPELLRRLERF
EDDPEGFRAAGIDAVTKICERLLAEDVLGLHFYTLNRSTATREIVDRLGLADSPVPVPAV
A
>A0A1H3FWA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aidingimonas halophila|TrEMBL
MSSYVSSLDISFEFFPPSTEAGHEKLMRTRDALAERDPRFFSVTYGAGGSTQARTTQTVQ
AVRECGIDTAPHLSCIGSDKSTLRQLLADYRQTGIRKLVALRGDLPSGMGVPGELRYANE
LVEFIREETGDHFEIAVAGYPESHPQAPSFERDLENFVRKVKAGADVAITQYFFNPEAYY
HFVERATAMGVEVPIVPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIRAF
GEEVISRLCQRLLDDGAPGLHFYTLNQADATLKVLDNLS
>A0A2U2CQ60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritimibacter sp. 55A14|TrEMBL
MSDPLNIVGQMPPDAPPPEGHVSHSRLERVLRSGRFAVTAELNPPDSADPADVYEAAQPL
GEVADAINATDASGANCHMSSIGICALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAALG
VQNVLCLTGDGVGVGDQPGAKPVFDFDSMTLIRTIRTMRDDGAFLSGRKITSRPKLFIGA
AENPCIPPYEWRPNRLAKKIAAGADFIQTNYIFDIPLFETFMQRIRDEGLDEKVFLIAGV
GPLASARAARWMRSNVPGIHIPDPVIERLEKAEKPSEEGKRICIELLQQVRQIKGVSGVH
LMAYRREHLVSSIIEESGILAGRRRKKMPGHR
>S6GQS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Osedax symbiont Rs2|TrEMBL
MFHQLTIMDIRIMHANLATRLADPSRGVYFVGTTPPRAEVAEMDMQVIADKLLDRLIAID
YDGLVVYDIQDESSRTQTPRPFPFKATYDSLTYSKVLSDKSGLPTITYKSVSARSKNEFN
QWLEQAWVEYGIQNIVLVGSPSSSGTINLPLKEAYQTLAEHQRSFNLGGVTIAERHHKKG
DEHIRLKQKSVDGCNFFISQAVYNADATIDLLQQYSALCKKNAEKPKRIILTFTPCGSEK
TLDFMHWLGISTPSAVKTRILNAQDSLAESITVCEENLQQILNYCMDLDIPLGLNIESLT
NRKEEIDASIKLFKLLKATLDLNLAKKFLSQ
>A0A4R3Z7M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Longibaculum muris|TrEMBL
MISQEFPNDFCLSGACYPEVHNEAACFEDDLKALKEKVDAGAEYLITQIFFDNNYYYRLV
KEARKRGITVPILAGIMPITNSKSLLHTAKMCGCSIPYQLSTMIESYYDYPEAMKEIGIN
YATHQIIDLITNGVDGIHIYTMNKPDIAKAIFNNIPTVLKELNHE
>A0A7G8W9X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella sp. PAMC22761|TrEMBL
MKVTDHIKNANGKTLFSFEIIPPRKGNSIQQLYNNIDPLMEFKPPFIDVTTSREEYLYIE
KQGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGLNNV
MALRGDAMKHQQYFEACDGGHQFAKGLVSQIQNLNNGHYLHDVLEADDKSDFCIGVAGYP
EKHLESPSLKTDLKRLKEKIDAGADYVVTQMFFDNNKYFEFVKAAKAEGINVPIIPGIKP
LAVKRHLQLLPQVFKIDLPEDLIEAVDGCKSNEQVRQVGVEWAIQQSKELQQAGVPVLHY
YSMGKSDNVKAIASELF
>A0A2V1AXJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] haemuloni|TrEMBL
MATVTAKIKALEPGERFCSFEFFPPKTDAGFRNLLARLSRMMALNPLFLTVTWGAGGSTA
EKSLDLAATCQKELGVTTVLHLTCTNTNKEIIEDALKRAKEAGIRNILALRGDPPRTEEY
WTPNCDFSNAVDLVRFIRQEHGDYFCIGVAGYPEGHVEGADASAQDPKKDLPYLIEKVEA
GADYVVTQLFFDVDKFVAYEQLLQDTPQLKNIVLIPGIMPITTYRVFIRATRLSHASVPK
NILDDLDAHINDDDMVKNIGLDVVTKMISEIDSRTNGRVRGYHFYTLNLEKAVASIINRS
PVLQNMIPHNKSVQHDDAIASDSDDDLPAGTVIPAKNGRRKSSVNENQLASADAMDAKRA
LVSKALSKDPKAIVDISTGKGVLGKDATWDEFTNGRFGDSNSPAYGEIDGYGPNLKLHSN
KEVQETWGEPKSTADVTKIFVDYLSNKITVLPWADSELSPETALIQEELFELNERGWFTL
ASQPAINSCSSRDKILGWGPPNGHIFQKSFVEFFIPKKQWEEDLLPRISTQVDDKTITYY
CGDASGHISSNLPISTGKNSNTKSAVTWGVFPSKEVLQPTIIDYESFKAWNEEAFLLWLE
WARCYRKDSDSYKLLNSVYNDYYLVSLVHHDFTDEFVLWTTLLSD
>A0A3N2LJL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Isolate-077|TrEMBL
MRVIDHLQANPGRTAFSFEILPPLKGNSIEKVYNIIDKLRDFDPKYINITSHHSEMIFKE
MPDGSFRPQKMRKRPGSVAIASAIQNKYGITAVPHIICKGFTRDETEYALIDLNFLGVHD
LLLLRGDIKGPEKSDDPTKINRHATDLQAQVNDFNRGIYADGETFEPNATPFSYGMACYP
EKHEEAPNMDSDLYYAKQKVDGGADYLVTQMFFDNSKYFEFVERCRKAGITVPIVPGIKP
VVFANQLNVLPRVFRSDIPEAFASELRKCKDDAEVREVGIEWCIGQCRDLIAHGVPSIHF
YTLMASESVRRIAKEIY
>A0A4S4NGS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliishimia ponticola|TrEMBL
MSAPSVSFEIFPPASMTASFKLWDAMARLSTFAPDYVSVTYGAQGSAQDKTLDTARAVME
QTKLPVASHLTAARASKEDVMTRAQGFADAGIRDIVALRGDPDSAGAEFAPHPDGFASSV
ELVSALAETGNFNIRVGAYPESHPSASSQQQNIDYLKAKFDAGASEAITQFFFEADTFLR
FRDACAKAGITQRIVPGILPPTNWTRARSFAERCGASVPDWLDQAFDAAIRDDRADLLSL
AVTTELCSTLIDEGVDHLHIYTLNSAHLTERLCLALGLAPEQPVLRPVLRDVA
>R7NS30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:581|TrEMBL
MKLSNLYTKAKEEGKTVLSFEVFPPKKTSGIETVYKAIDELAKMNPAYISVTYGAGGTEA
NNTAIIAEKVKSLGVEPLAHLTCVNNDKVSVEKELDEFKSKGIENILALRGDIVPGVEPK
KDFLHASDLCSYIKARGDFELAGACYPEVHMEAKDMVEDIKNLKHKVECGAEHLISQLFF
DNEVFYKFQDMARCAGIDVPIAAGIMPVTNTKQIQRMVSMCGASLPANFSRIMQKYENNP
EALRDAGIAYAIQQIVDLIAHGVDGIHLYTMNNPYVAGKITEAIGSML
>A0A4R9ZBS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.205.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVGRILKETSLTPAAHMTCVDAARDEVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKGAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLHNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAT
GSAAA
>A0A2P2GLL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces showdoensis|TrEMBL
MALGTASTRTDRARTVRDILAEGGTSYSFEFFAPRTEKSEQSLWNAMRRIEAVAPSFVSV
TYGAGGSTRGGTVKATQKIASDTTLTPVAHLTAVDHSIAELRNILGQYADAGIRNMLAVR
GDPPGDPLGEWIAHPEGVHYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSAEKAGCDTPIIPEVMPVVSVRSLERLPQLSNATF
PEDVKDRILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSKATLEIYENLG
LHQQS
>A0A556UNL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus campinensis|TrEMBL
MTDRYYSFEFFPPKTAEGTEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
DGIEAAPHLSCVGSTRDSIRQILKTYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFHIEVAAYPEYHPQAKSPRHDLDNFVRKVRAGADSAITQYFYNADAYFRFVD
EVRAQGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTGLCERLLAAGVPGLHFYTLNAAGATKAVWERLKL
>A0A2R8BGP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ascidiaceihabitans donghaensis|TrEMBL
MTSPAISFEVFPPKSIDASFRLWDTAQALAPLDPRFFSVTYGAGGSTQDLTHDAAATLRR
TSGMPIAAHLTCVGASKSQVMATAQKFAKAGITDIVALRGDPVQGDAAFTAHPDGFANSV
ELIEALAATGKFTIRVGAYPETHPDAVSDQQNVEWLKAKLDAGAAEAITQFFFDPEHFLR
FRDACVKAGITAPITPGILPISNWKSTVSFAERCGASIPADLAQAFENAVRDDRMDLLSI
AQCTELCDDLMCEGVDALHFYTLNRPDLTREVCHALGVTAASGIRNVA
>A0A6C1E8D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces pastorianus|TrEMBL
MKITEKLEQHRQSSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPVSMIDDALENAYHSGCQNILALRGDPPRD
AQNWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPSKDSQLDLAYLKQKID
AGGDFIITQMFYDVDNFIAWCAQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQVSIPQS
FLAELEPIKDDDELVRDIGTNLIVQMCQKLLHSGYVSHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANRCLELWATPTSIHDVACLVISYLNGNLKCLPWSDVPIN
DEVNPILSHLVELNQHSIITINSQPQVNGIRSNDNVHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIETLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILDEWKLNMDNNDKPQSSRFIQSLIDDYCLVNIVDNDYISPEDQIHSILLAL
>A0A176J6P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. SJS|TrEMBL
MGFLEDLQNEILIADGAMGTLLYSHGIDRCFEELNLSNPDQVQSIHEAYINAGARVIQTN
TYGGNHIKLSRYGLEDDIRAINSKAARLARKAAGSQAYVLATMGGVRAFKKSSHTLDELK
RSFREQLYVLLNEDIDGLLLETFYDLEELKTVLEIARKETSKPIVANVSLHETGVLQDGT
PLEKGLKELEALGADAVGLNCRLGPYHMLESLEEVPLLEKAFLSVYPNGSLPSVEEGRLV
YESDEGYFAESALAFRNQGARLIGGCCGTTPKHIKAMADALRGLAPIKEKAVKQRKPVTV
HERLEPAYPPLHQIVKERRSVIVELDPPKTLSLEKFFKGAEELKKTGIDSITLADNSLAS
PRVSNAAVGTQLKEKHDMRPLIHLTCRDRNLIGLQSHLMGLHSLGLTDVLAITGDPSKIG
DFPGATSVYDLSSFDLISLIKQFNEGLSYSGKALGGKTNFTVAGAFNPNVRHLDKAAERL
EKKIACGADYFISQPIYSIQQMEEVHDAVKHLPAPLYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIRETMAKAGTDPLQSKKEGIAIAKDLIDAAFDLFNGIYLITPFLKYEYSVELAEYI
REKEKQRSEREFSHVQHS
>A0A855WEJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter schindleri|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADNFDADIKRFCEKAHAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A6H0T9A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurellaceae bacterium RH1A|TrEMBL
MSYAREIDLLNQSVADLNGKINVSFEFFPPKNEKMENLLWESIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKSIQQETGIIAAPHLTGIDASPDELRAIAQDYWDSGIRHIVALRGDEP
AGYAKKPFYASDLVALLKEVADFEISVAAYPEVHPEAKSAQSDLLYLKQKIDAGASRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLERMAKITNVKIPSWMHKMYEGL
DEDQTSRNLVAASIAMDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGVRP
>A0A371YVC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sichuanensis|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDLDIQRFCDKARAGANAALTQFFFNPDAYFYFV
DRIQKEGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A315AW04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. T6-5|TrEMBL
MSGLKLPISLEFFPPKTPEGAEKLRAVRQQLYALKPEFCSVTYGAGGSTQEGTFSTVSAI
LSEGVAAASHFSCIGATKASVREELATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLV
AFIRAETGDDFHIEVAAYPEIHPQAKSPESDLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDVHKLGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGFGDDLDSIKAFGL
DVVTELCDQLISAGVPSLHFYTMNQSATTAEILRRL
>A0A3D3W5A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MRLTELFNSRRFVLSIEMFPPKTAESSEALKRSLLSLNRFRPAFVSCTYGAGGSTRGQTL
DWCQWIQQTLQCPAMAHFTCVSSTVTELSAWLDEAWQAGVRNIMSLRGDPPAGQQVFTAA
EGGLSHASELTALIRRQYPDMGIGVAGYPEKHVEAVSMDSDLHHLKTKVDAGADAIFTQL
FFINDSFLKFRDQCSALGINVPIVPGIMPITDFARIRRI
>A0A5C8ST53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. WL69|TrEMBL
MPTASQHRASRDGYRPIRVSIEFFPPKTDEMEQILWKSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETGLKPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPQDGVG
TTYRPHPGGYAQTADLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFENDIYLRYVDKVRAAGIDIPIIPGILPVQNFKQSANFARRTGASVPYWLAARF
EGLENDPDTRRLVAAAVAAEQVLDLVDQGVNDFHFYSMNRSDLVYAICHLLGLRAPAPKV
EAAKAAA
>A0A2D5SBK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MTLAAHYGPRKCGLSFELFPPKTDAGESALFRHVEQLMQFQPSFITCTYGAGGSTREKTM
NIVDGVRRRFNIPVASHLTCVNASIDELRAFLEDAGRRQIDYIVALRGDPPQGETEFKST
AGGLQYANQLVELIHAEFSHFGVAVAGYPETHQEAVSADADLENLKRKVDAGADIVITQL
FYNNEDFFRFRDRVQKVGISVPLVPGILPVTNLAQIQRITAMCGAQLPAGFVTALGQSED
SDSQFRVGVDFATQQIQDLMDRGVPGVHFYVLNKSQATSEILTALNLERQP
>A0A2D4WR72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MHMSDVIKRDTTTFSFEFFPPSTDTGWETLETTIDELTRLGPSFVSVTYGAGGSTRTKTH
ELVRRLKESSGLDPVPHLTCVEHDSAQIHDILKVYADAGISNILALRGDAPSGTTQGDHF
KHFQHAADLIKTISEFNRSGAHPDPRGFSIGAAGFPEGHPETPNRLTQMNHLKSKVDEGV
DWICSQMFFDNRSFLDWQERCRLKGIDVPIFAGIMPVTSLSGLKRMAQLAAGTNFPAALL
RALDRAGPDPENIERVGIHWATEQCLQLMDEGVQGIHFYTLNKSKATVEIFKSLGVSDSD
QLRGRREPGIKSVRR
>A0A5C8S1X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. WL12|TrEMBL
MPNAIRHRASRDGYHPIRVSIEFFPPKTEEMEKILWSSIERLAPLGPKFVSVTYGAGGST
RERTHNTVARMVTETGLKPAAHLTCVDATRDEIDAVVQSYWDAGVRHIVALRGDPAEGVG
HAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFENEVYLRYVDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLEGDVETRRLVAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKV
MAAKAA
>A0A2E6MTR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MVSLAQYYTSEHKGLSFELFPPKTEKGEAALMRHMDALMQFAPDYVTCTYGAGGSTQSKT
MDVITAVKEAFNVPVASHLTCVGSTADDLRRYLQNAXQQEIDFLVALRGDXPQGDEKFEA
VAGGFSYANELVEFIRAQFPNFGIAVAGYPEVHQEAPSAEVDLDNLKRKVDAGADIVITQ
LFYKNTDYFDFCDRCVKAGITIPXVPGVLPVTNLAQIQRITSLCGSSLPQDFXTKLSQRE
DDTQWQFEVGVEFAAAQVQDLIASGAPGVHFYVLNKSQATRRVLEAAGW
>A0A3B9D2T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MRLPEIFASNPFVVSIEIFPPKTDSGEEALRRHLQTLVTHQPAFISCTYGAGGSTQAKTV
SWCREILNDLQRPAVAHFTCVNSTREQLNQWLDEAQAAGIRNIMALRGDPPQGQETFEAV
DGGLSYANELVELVRSHPGDFGIGVAGYPEKHIQAPSPEVDLENLKRKVNAGADAVFTQL
FFDNECFYRFRDSCDQLGITCPVVPGIMPVTDFARIKRITSMCGSSFPDDLSSRLEAVQE
DADAQFEIGVEHAIKQCEALRESGVPGIHFYALNKSQACQKILESLQS
>A0A2D6SX01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MNSDSFQPTRVGDVYRSGEFRLSIEVFPPKTAKGDATLFRTLDALSRFRPAFVSCTYGAG
GSTQSRTIEICVDIQKRYELTATSHFTCVGATRDEILASLGTLQQAGVHNIMALRGDPPE
GQEAFRAVDGGLAHANELVELIRENFPQMGVGVAGYPEKHPEAVDAASDVEHLKRKVDAG
ADTVFTQLFFVNGSFLSFRERAENAGVQVPIVPGIMPVTQFARIQRITAMCGAAFPAALA
EPLEAAQDDKEAQFEIGIEYAIRQCQELMEAGVPGIHFYALNKSTACERILTALGLESVA
R
>A0A1X9ZBA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriaceae bacterium GW460-11-11-14-LB5|TrEMBL
MKITDHIKNAKGKTLFSFELLPPVKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QANGLLQKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHCYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMSTDFKYLKKKVEAGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNNEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKKIAKAIF
>A0A0C7IGP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paeniclostridium sordellii|TrEMBL
MSLLKEALESGKFAVTAEMAPPKGTDLSHLIKCARAVKGRVHAVNVTDFQSAVMRTTSLT
TCKLLKDEGLEPVLQVTGRDRNRIAIQGELLSAGVFGIKNMLALTGDHTIVGDHPQAKPV
FDLDCVGILKTAQKLSQGTDMVGNQLKGAPKFYLGASVTPRYTPIEVQLLKMKKKINAGA
EFFQTQAVYDIDTMRYFRSHTKDMNTKVLAGIIPLKSPRMAKFMNANVPGIYVPEELIDR
LKSVGKENWVNEGIKIAGELIKQLKEEDLCDGIHIMAIGAEENIPAILDAANI
>K4RBS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces davaonensis (strain DSM 101723 / JCM 4913 / KCC S-0913 / 768)|TrEMBL
MALGTASTRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGTTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKNSGDFCVGVAAFPAMHPRSADWDMDVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVDAAGCATPIIPEIMPIASVKTLERIPSLTNAAF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A7Y1VMZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eudoraea sp|TrEMBL
MKVLDHIKNSKNQTLFSFEIIPPVKGRNIQELYNNIDPLMEFNPPFIDVTTSREEYVYID
KEGLLDKRLTRMRPGTVGICASIKHKYNVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNI
MALRGDAMKEEKYFNPSEGGHLFASDLVKQIKDLNRGQYLHEVIESDDCSDFCIGVAGYP
EKHMEAPSLHSDLKWLKHKIDLGADYVVTQMFFDNKKYFEFVEAARAMDINVPIIPGIKP
IAIKKHLHVLPQVFRIDIPQDLIDAVESCKNNKEVRQVGIDWAIEQSKELKAAGVPVLHY
YSMGKSTNIQAIAEGVF
>A0A0F7F9B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus durus ATCC 35681|TrEMBL
MKLDLRSAWAAKVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEEVHRSYIEAGAEL
LESNTYSANYDKLSKFGLESKVEEINRAGIRIARQAAGSTGYVVGAVGSIRAGKRASLSA
SELKKYFGQQIGAMLEENVDGILLETFYDLEELHLALRTARKLSNLPVICQFAVDETAMT
MDGLTLPEAFRILEDDGADVIGFNCRTGPIGVKRALGTLQGKLTLPVSVYPNAGMADYVD
GHYKYGASPEYFGEMASVFAGMGCRIIGGCCGTTPQHIAEISAALTGYEPLPLPEPLPRE
KISVRIQESLADDSFADGGEPTLIDLVMERHTVIVELDPPRDLDISKFMKGAEALRRAGA
DALTLADNSLAVTRMCNMALGSLVQQKTGLRPLVHIACRDRNLIGTQSHLMGLDALDIDH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVTGAAFNP
NVKHLGKAIERLEKKIAFGADYIMTQPVYDKELIHSIADSTAHLNIPIFIGIMPLASGRN
AEYLHNEVPGIQLSEEVRSRMRGLEGEAGRAEGVAIAKELLDAATERFNGIYLMTPFMFY
DMSVQLMEHVWAKSGRQLSPLFR
>A0A6B8LXN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystis parvus|TrEMBL
MFNALHPSASSKRFNISYEFFPPKTPEMETQLWESVKRLERLQPHFVSVTYGAGGSTRER
THAIVARMARETRMKPAAHLTCVSSSRDEIDDILRGYWDAGVRHIVALRGDPPTGVGTKF
EANPEGYAHSSDLVRGIRRLHDFEISVSTYPEGHPESGSIERDLDALEAKIDAGATRAIT
QFFFDNDIYFRFLDKARGRGITIPIVPGIMPIRNFRQVANFATKAGASVPRWVAERFEGL
DDDAETRALVAATTVVEQVMGLARAGVEDFHFYTNNRADMVFAICHLLGVRPVREKVNA
>M2ZQ55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis decaplanina DSM 44594|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTPRTLHTSIKLSGAPAPRRLLDRLEPLA
GDPKAFRAEGIDAVTELCERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>J0NMI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces massiliensis F0489|TrEMBL
VPAPAVPGAVPAPAVPGAVPAPAAPTARPSLSLELFPPRPGRHVTQTWGALDRLLGTRPD
FASVTYRPSFVTSGTSDLGSPGRPDGPGGPHSADTTDSTGNATGTRTHVHVRRERNPAED
VVSHVLSRSEVPLMAHLTCIGYRKDSVVEIVRHFLDMGVRRFLALRGDPPRGFAAEDVAG
ELPHADDLVRVIREVEADYFDDGARHLQVAVAAYPADIDHGTGIEVLAAKQAAGADLAIT
QVFYDPEDYLALRRAALYSGVTMPILPGIIPLTDLKRLTRLEALTGVCVPADLVRTLERS
DGVAAAAAGIDATLTLASAVLDGGAPGVHLYTFNRVRPALDVISHLRLGGILNGSTPDTA
VQREVRRDYLNATPGGDRGPSARMPGATRP
>A0A239M8P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ekhidna lutea|TrEMBL
MKVTEHITNADKTLFSLEIIPPKKGDSIKNLFAQIDPLMEFKPPFIDVTYHREEYVYKER
ENGLLEKRSIKKRPGTVGICAAIQNHYQIDAVPHIICGGFSKEETENALIDLNFLGIDNV
LALRGDNIKSEREFNPEPDGNAYASDLVEQISAMNKGEYLDDELQNAIPSNFCIGVAGYP
EKHFEAPNMNFDLKWLKKKVELGAEYIVTQMFFDNKAYFKFVDDCRAIGINVPIIPGIKP
VAVKRHLTILPNIFKIDLPDELEQEITKCKDNAAVKELGIEWGIQQCRELVDKGAPVIHF
YSMGKSDAIHRIAKEFF
>A0A1E4E9V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. SCN 67-24|TrEMBL
MMNAFRPSRHGSRRPRVSFEFFPPKNEEMEVSLWESVRRLEPLGPAFVSVTYGAGGSTRE
RTHNTVKRMVDETALKPAAHLTCVSASCGEVDEVIRAYWEAGVRHIVALRGDPAGGLGTV
YEPHPEGYHQTSDLVAGIRKVGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAI
TQFFFDNDVYFRYLDKVRARGIEIPILPGIVPVQNFRQTAGFARKTGASVPQWLADRFEG
LEDDPATRRLVAAAVCAEQVLDLVDRGVSDLHFYTMNKADLVYAICHLVGLKPEKVQAQQ
VAAE
>A0A5J5FXC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Affinibrenneria salicis|TrEMBL
MSFFHANQREALNQSLAELQGHTNVSFEFFPPSNHEMETTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKAIKERTGLEAAPHLTCIDASRDQLREIAQDYWQSGIRHIVALRGD
LPSNGGKPEMYASDLVALLREVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGATRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATLTNVRVPNWMTAMFD
GLDHDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPVADAA
>A0A1G4INM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea dasiensis|TrEMBL
MRVSEKLQKNLESNEKSKPTFSFEFFVPKTSQGVQNLYDRMDRMYQTRPQFIDITWNAGG
KLSQLSTDLVSTSQSVLGLETCMHLTCTNMPVELIDDALAKAYESGCQNILALRGDAPST
TGEWKQCEGGFAYAKDLVSYIRKKYGDHFDIGVAGYPEGHPEEEASPQLIQFLKEKIDAG
ANFIITQMFYDADIFIDWCRQVREAGIEVPIIPGIMPITTYAAFLRRASWCQIHVPDEFM
AALDAVKEDDQAVREVGTQLLTGMCQRLLDSGYVTHLHMYTMNLEKASIMILDRLGLLTE
DEDIFRDDVVPMPWRKSLHPQRRNESVRPIFWQKRPYSYVARTSQWSADEFPNGRFGDSS
SPAFGDLDLLGSALIRQSPQRAVELWSAPKAFSDLTGLVVAYLQGNTKCLPWCDVALNHE
VDSILPQLLELNQNGILTLNSQPRVNGSNSGDKVIGWGPSNGYVFQKEYLEFLLPKDKLS
TFVNLVEGGSTLTYFAVDATDKLYSNHPDDTAANAVTWGIFPGREVLQPTIVEKVSFLAW
KEEFFQILEEWGSILGEQGHSESAELLKSVIQNYTLVNIVDNDFVTEGDRIYDRLRHLY
>X6GZE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L2C084A000|TrEMBL
MIGRQRDENPAGIDLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A1H6P5L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fuscovaginae|TrEMBL
MGLLKNALGEQAFVCLVEFVPKPSAQHFGAFEQLMQRSTLCGWPMIAAVADRVGGNLDLS
PLDAIAEFNGSRSALVHFSGKDRERRELLAQLERMAAAGLDELLMLTGDRLPGHDPGQRP
VRYLESVPALQIVRQARPEWLLGAALNPFKYLEEEGAAQYFKAGKKLAAGADFLTLQLGF
DIAKQREALAWMSRQATPKPLLACVMGLTKARAAMLDQVAGVVITQSMRDLLEAEEAVSK
AYAQERSISRLALQIIGLQRMGYAGIHLSGVHQLKQLQALEQALTDWQTSLHTQAQWDAA
WIASWSMPDIPGVTFHAGASNWRLGESYVQASCREKVRYRLMSGVHSHLFNRTSRLSQAF
GWVVTRPLWSTATGAGWLHRVERSLKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTRLNRCEFGDRECVHSVKYRTAKAVGQEAVLTDRLIPCIEVETRHQSSWPGWFEADVP
VPADGWKAAQG
>A0A8B9TAA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anas platyrhynchos|TrEMBL
RELTMVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQD
SGDRWFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIAN
TAVNYCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNY
AVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYESDLKHLKEKVLAGADFIITQLFSSET
FIKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIR
NYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHP
KRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRE
ELLKMWGEELTCEESVFEVFTCYISGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVN
RRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYESR
VNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQW
AKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A1A9UHM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glossina austeni|TrEMBL
MSSNITNTTHLGAHFLPKVDTPPLESAKLESCEPKFRFSEQQLRKYPKTQQLKIAVAEKI
EKKEYFYGIEILARNHNPKLMLDYTKFGKMLPLFTSLVWLGLDYSRVANVGKVESVRVAK
KLKDNQREMLIAPHLSCYGLDTKRLKEFMELNFTNIVIVRGDQYDNEQEFKYASQLVAQI
KRECQDSITIAVAGHPEGHPSVSTMQEDMKFLIEKINGGADLIITQVCFKAQALIDFIKS
CRLHSINIPIILGIYVPDNIKSLQFLMELTKIEMCEEDLQQYRYHASNGTDAFRFFAAQK
VSQMILTVLKTQDINIYGIHFFTMNKFGMVTKVLEELRKYIKI
>A0A3N9Q8H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus rhizophilus|TrEMBL
MKPDLRSAWASKVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIDEVHRSYIEAGAEV
LESNTYSANYDKLSKFGLESKVEEINRAGIRIARQAAGSGGYVVGAVGSIRAGKRASLSA
SELKKYFGQQIGAMLEEDVDGIMLETFYDLEELHLALRTARKLSNLPVICQFAVDETAMT
MDGLTLPEAFRILEEDGADIIGFNCRTGPIGIKRALGTLQGSLTLPVSVYPNAGLADYVD
GHYKYGASPEYFGQMARDFADMGSRIIGGCCGTTPHHIAEISAALKGYEPLPLPGPAPKE
KISVRLQESLADDSAADGREPNLIDIVKERHAVIVELDPPRDLDISKFMAGAEALRRAGA
DALTLADNSLAVCRMSNMALGSLVQQRTGLRPLVHIACRDRNLIGTQSHLMGLDALDIDH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKAKFIIGAAFNP
NVKHLGKAVERLEKKIAFGADYIMTQPVYDRELIHKIADATAHLNIPIFIGIMPLASGRN
AEYLHNEVPGIQLSEEVLGRMKGLQGEAGRAEGVAIAKELLDAATERFNGIYLMTPFMFY
DMSVQLLNHVWAKSGRQLSPLFR
>A0A672ZKG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaeramia orbicularis|TrEMBL
MVNQVPRGDGSWQSFKSDSSGASTSGGDSSKDSSRCSTPVLEADRSDRLRDKMRRRTESG
DRWFSLEFFPPRTASGAEEGFNPFIFQSRQLFNGKKVKKNHFPGLDSSLRFDRMGSGGPL
FIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTTHKITGYLEKAKRLG
LKNIMALRGDPVGADWEEEEEGFNYAIDLVKHIRSEFDDYFDICVAGYPTGHPEAGSYEE
DLQHLKEKVDAGADFVITQLFFRADTFLKFLDDCRAIGITCPILPGIFPIQGYQSLRQLV
KLSKLEVPEEITKVIEPIKDNDAAIRNYGIQQAVQMCRVLLDSGKVSGLHFYTLNREVAT
MEVLRQLGLWTEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQDWDEFPNGRW
GNSSSPAFGELNDYYLFYLKSKSTKDALLQMWGDELMNEQSVYEVFTCYITAQPNHRGHK
VMCLPWNDEPLAPETNLLKEELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVFQ
KAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVHGQNRTNAHDMQPNAVTWGIFPGREI
VQPTVVDPVSFMYWKDEAFALWIEQWGKLYEEESPSRMIIKYIHDNYFLVNLVDNDFPLD
SCLWQVIDDMFELLDTPPDPLSDGTASE
>A0A0D5BS07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia miricola|TrEMBL
MKVTEHIAQSKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGEKYFEPTKGGNRYASDLVTQINDLGKGKFLHGEISGNDLNNSFCIGVAG
YPEKHLEAPSMQYDLKMLKQKVELGADYVVTQMFLDNQKYFEFVKLAREAGIDVPIIPGI
KPLAVKKHLQLLPQVFKIDIPEDLVNAVSQCKNNEAVKQVGIEWCVQQCKELLDFGVPAL
HFYTMGKSDNIQKIVSEFF
>A0A388SMA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupidesulfovibrio sp. HK-II|TrEMBL
MKIRDRIAASTSPFYSLEFFPPKERENWPGFFATVERLKALNPLFASVTYGAGGSTQDNT
LEITSHLKNVMGLEPMAHLTCVGATRERIADYLRRLREVNVDNVLALRGDAPKGQDFDWD
TAEFRYAADLVRFTRSEQPDMGVGVAGYPAAHPESPSFASDLRHTADKVNAGADFIVTQL
FFDVREYFDFVERLRGLGVDKPVLPGILPIQSLESVRRILSLCGANIPGNLYLELEAANE
KGGAEAVKEAGIAFAQRQIRTLLDGGAPGIHLYTLNRADTCLRIAEAVGMK
>A0A2S5KR62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium 228|TrEMBL
MSKPNFSLEVFPPKTAATTLSLWKASQELAPFKPEFISVTCGAGGNAPGDTTKEVALVMA
QQAHCPVAAHMTCVSGSREELLQLARDYWQSNIRHIVALRGDMPGQERYTPRNDGFAYAD
ELVAALKEVADFDISVAGYPEGHPDSSSMDKELEYLKKKADAGANRIITQFFFDPEVFLR
YRDRVAAAGIKAEVVPGLLPVLNFKKMTAFAARCQTSVPEFLHKMFEGVEAEDIDHRLLA
MNILSHQITRLHTEGVNFFHLYTLNESMLTRHVCRWIRSAF
>A0A5B8STM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pistricoccus aurantiacus|TrEMBL
MSKHEHPLGISFEFFPPATEVGRDKLRHTRDALAKRQPRFFSVTYGAGGATQLRTADTVA
MISESRINTAPHLSCIGSDKGELRELLVRYREWGIDSLVALRGDLPSGMGGAGELRYANE
LVEFIREETGNHFEIAVAAYPETHPQAASAAKDLDNFARKVKAGANLAITQYFFSADAYF
HFVEQAQALGIEIPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLETYGDDSESIAAF
GEEVVTRLCQRLLDGGAPGLHFYTLNQSAPVLRIVDHLGE
>A0A2G4T3X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus microsporus ATCC 52813|TrEMBL
MKVIDKIKKAEAENRSFWSFEYFPPKTPQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
ELTTEIVATAQSVYGLETMMHLTCTNMPIQQIDDALEAAKKCGCQNILALRGDPPKGQAN
WESCEDGFEHAIDLVRYIRKKYGDYFCIAVAGHPEGHIDNPDKEDDLLRLKEKVDAGADL
VVTQLFFDVDMFIEFYKKARAIGITVPILPGVFPIQNYSGLKRVIAFNDNFVPQKIWDDL
EPIKDDDTAVKEYGINLAVEFIKRFREVGINGFHLYTFNLERSSRLVLERLELVAPLESI
KPLPWSPSLNTKRAKENVRPIFWKNRTKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
INLRYPVEQCVNMWGTPKSVDDVALTFARYCKGEISGIPWSSQQLDPETDIIRQRLAAIN
LLGYFTINSQPAVNGVKSCHPIYGWGPKNGYVYQKAYLEFFVSPEKLNELIDKISQNPQV
TYYAVNKQGDLRTNTTSDEPNAVTWGVFPGKEIIQPTIVESVAFMAWKDEAFELWNRWAR
IYERDSESAKLILDITDSYYLINIVHNDFQDENGIWRLFDLEIDGEISRKLLQSSVAR
>S2N980|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei subsp. paracasei Lpp225|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTRKQVDAELRGFQDAGIDNILALRGDIPKSGRVS
TDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A520EBQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp|TrEMBL
MSNRPKLPLSFEFFPTKTPEGAVKLRAVRQQLYAQKPEFCSVTYGAGGSTHNGTFGAVRE
ILEEGCAAASHFSCIGATKATVRAQLAELKAMGVKRLVALRGDLPSGYGIGGEFHYASDL
VRFIRDETGRDFHIEVACYPEVHPQARSPEADLQAFATKVRAGADSAITQYFFSAEAYFR
FVDESRKLGLDIPVVPGVMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDIASIKAFG
LDVVTDLCAR
>A0A2W5YNP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eremiobacter sp. RRmetagenome_bin22|TrEMBL
MRIDRILSGSGPHFSFEFFPPKSDDAVQALLQTAAALQALGPAFVSVTYGAGGSTRARSL
QVVKAIAQELRIEAMAHITCVGASKDDLRAVFRDVADAGIENVLALRGDPPRGSAHFEPP
ADGLAHATDLIALVQAEFQFCVGAACYPEVHPESLDANSDLLFLLKKQEAGAQFFITQLF
FDNAYYFRFVKRARSVGVRVPVIPGIMPITNADQIERFTRLCGATLPLRLRTALQSRSGD
PEAVAELGVAYATLQCVDLLAAGAPAIHFYTLNKSPASRAVVSALLAARPWERSPGLRYL
GSPTTAPR
>A0A552LJM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis flos-aquae Mf_WU_F_19750830_S460|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDSNDKSLPDGSLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDMAGIPPIHN
>A0A3D2R108|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilaceae bacterium|TrEMBL
MKELINYSFEFFPPRTEEGNVKLQSTIEALKAFDPEFFSVTFGAGGSTKEKTLETVLNIK
KMGSTAVPHISCISSTRNEIQELLMRYKKNEIKNLVVLRGDNPSGVASHGEFKYANELVS
FIRAETSNYFNIHVAAYTECHPEAKSCTDDLDNFERKISAGANSAITQFFFNVDSYFKFV
EACQLKGINVPIVPGIMPIYNIKQLARFSSNCGAEIPRWLRLKLESYGDDISSLREFGVD
VISELCETLIQYGVPSIHFYTLNESGIITKIINNLKN
>A0A8E4A8K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia vermicola|TrEMBL
METALSFEISAMPKIDNTLERLLKNTEALTPLFYTVNTEIGKTEWRDTYNTCCQLKNLTH
VNVVPHVAINNKDECELCFIIEEYLKNDITELFVIRGDRHRFDEKLPFNYGIELIDFIRG
RYPEVMIKSSVYPDYHKESITPEREIDWLRKKLQLGVTELISQLCLNKNAFSYMKMQLGN
DSPITISMMPILNFSFIESFLKNNAIDYPLWIKKHIRPSNINNHREFGIQLTQFLIEEYI
KENKRLHFFTLNNAEIVKKLFDKLR
>A0A7X4GT53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella alba|TrEMBL
MDNPNFSIEFFPPKTAEGAEKLRATRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILN
AGEDAAPHLSCVGGTRESIREILTEFKSHNIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGDWFHIEVAAYPEVHPQAKSPQDDLLAFERKVKAGANAAITQYFYNADAYFQFVE
QTQKLGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VSGLCERLLKGGAPGLHFYSMNQAAATTALWQRLV
>A0A094I6Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4518|TrEMBL
MKTTWKDIQPVPTSQEFLDIVLSRTQRRLPTQIRAGFQISRIRNFYTRKVKFTQETFSEK
ISLILDGFPRLQDIHPFHKDLLNTLYDADHFRIALGQLATAKHLIETVSRDYVRLLKYAQ
SLFQCKQLKRAALGRMATICKRLKDPLLYLDQVRQHLGRLPSIDPNTRTLLICGYPNVGK
SSFLRSVTRADVDVQPYAFTTKSLFVGHFDYKYLRFQAIDTPGILDHPLEEMNTIEMQSI
TAIAHLRSAILYFMDLSEQCGYTVAAQIALFQSIKPLFANKLVFIVINKIDVMRPEDLDP
ESQAQLQALLKPGDVEMLQLSCTTEEGVQEVKNAACERLIADRVAQKLKAGTNSNGAVGG
RLGDVLARIHVARPMNGVVREAFIPEAVKEMKKYDKNDPERRKLARDIEEENGGAGVFNV
NLKDKYMLENDEWKYDKVPEVLDGKNVYDFIDPEIEAKLAALEEEEEKLEAEGYYDSEDD
LEDAEDADIRMKAELIREKRILIRNAAKMKKSLKNRAIIPRTLTKAKLTDMEDHLDSLGL
DTTSLTTRARSQSRGRSVLRSRTGTEDVMDVDSPEYEAKMRAKSRARSQSNRREDGVPEG
TARTKAERIAKLGQRHRNRMARAGEADRHVAAAMPKHLFSGKRGAAKLQLHRGFFNCMVG
KPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHAQLTCEMVSVAQSVY
GLETCMHLTCTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEKWVATDEGFQYARDL
VGYIRKTYGNHFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATFIVTQMFYDVPNFLD
WVRKVRAKGINIPIIPGIMPISTYASFLRRCNHMNAKIPPGWIEAMEPVKNDDAAVREIG
RGLVTGMCRAILESGINHLHFYTMNLAQATRGVLEQLEMLPSEERPLKQALPWRQSLGLG
RRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDAYGIGLKGSNEQNIK
LWGEPKSVKDIANVFLRYLNADVESLPWSEAPISNEADVIKNQLVGLNERGLLTINSQPA
VDGVKSSHPVYGWGPLNGYVYQKAYLELLVAPELIDELLDRIAKDPEVTYYAVTKTGTLR
TNAPSDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDWAHCHEASSPSRNVI
QRVMETYYLVNIVHNDFHQRDGLFSLFEGLSVPNIDQPAEGDAAPAAGPTPAAAAAPATN
GNKVEDAPAAIVSNVLPVA
>A0A014EZ39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_3|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGVRIGGAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKAFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELNVLEELWNSLWQVT
TGKEFSPEIVRFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKDKLIPTVSIETRGTSSWKNWYLGAEA
>A0A6H2GKS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. SCLE84|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A850ZJC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tichodroma muraria|TrEMBL
MVNETQHPCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRYGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7G9RQM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diaphorobacter ruginosibacter|TrEMBL
MSQTSNTVFPVSFEFFPTKTPEGAQKLRGVRAQLYERKPEFCSVTYGAGGSTQEGTFNAV
KEILSEGVDAASHFSCIGATRESVRTQLAQLKEMGVRRLVALRGDLPSGYGIGGEFHYAS
DLVAFIREEMGDYFHIEVAAYPEIHPQARSAEADLKAFATKVKAGANSAITQYFFNADAY
FRFVDDTRRLGVDVPVVPGIMPIMGASQLMRFSDACGAEIPRWIRLRLQGFGDDVESIRA
FGLDVITALCEQLRKGGVPSLHFYTMNQSAATLEICKRLGI
>A0A2N7SBZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium intechi|TrEMBL
MNQFRFSRRPDIGDKIKVSFEFFPPKNDEMEAKLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVGRILNETSLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDLQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
GSAAA
>A0A2V5I8U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus indologenus CBS 114.80|TrEMBL
MHIKEKLSQNEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPVEKVDAALQAAYKAGCTNILALRGDPPREKEN
WEATDGGFRYAKDLVRHIREKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDNFIDWVKKCRNKGVAVPIIPGIMPIQTYAAFIRRSEWTKTRIPPDWLEAL
EPVKNDDAAVRNIGKRLVADMCRRLLESGLNHLHFYTMNLAQSTQLVLEDLNLLPSEETP
LQRALPWRPSLGLNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGQPKSIRDITHIFVDFLEGKLARLPWSDSPITTEANAIKDDLIE
LNKKGIFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLIPSYLLDDLIARIEKNG
YLTYHAVSKNGNLRTNTNDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQSVVDDWCLVNIVNNDFHNTSSLFDLFKDLNVKDLDTEIVVEDGETK
VHQNGVTNGVEATNGTVANGTTTELPVKN
>A0A258XFS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp. 24-45-7|TrEMBL
MKSHQEKLAFSFEFFPPKTAEGMDKLREARKELAKFNPEFFSVTFGAGGSTRDRTMETVL
EIQREGYQAAPHISCISSSKAEIRDLLHTYQSHGIKRLV
>A0A5C4R4U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus haeundaensis|TrEMBL
MTDLPPVDFDRWQPSYDPPPPGHVSGSRLERVLRQGHFAVTAELNPPDSADPADVFAAAR
PLARVADAINATDASGANCHMSSIGISALLTRAGIGTVYQISCRDRNRIAIQGDVLGAAA
MGVRNVLCLTGDGVGVGDQPGALPVFDLDSISLLRTIRTMRDDGMFLSGRRITSPPRMFL
GAAENPCIAPLDWRPDRLAKKVEAGADFIQTNYIFDVPTFARFMARVRDLGLDRRVFILA
GVGPLASARAARWMRSNVPGVHIPDAVIARMERAADPGEEGKRLCIELIQQIRAIAGVSG
VHVMAYRREHLVSEIIAQSGVREGRPAD
>A0A4Q2T0C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciceribacter sp. F8825|TrEMBL
MTRDDRHPQGKKRLGISFEFFPPKSEEMEGQLWTTIEALAGWNPDFVSVTYGAGGSTKAP
TLTTVRRLIADTTLPTAAHITCVDATREEVRHVAEEFIAAGVRRFVALRGDPQSGVGAAY
APHPGGFANAAELVAGLRDIGDFDISVSAYPEKHPESPDVAADIDMLKRKADAGAARALT
QFFFDNDVFERYLERVRAAGVTIPVVPGIMLIQNLTQLKRFASLCGASIPTFLDERFAGL
DDQPQARAEVAADVAAEQIEDLVRRGITDFHLYTMNRAPLVSAVLQRLGLERSGDARSGA
AA
>A0A1F0VSH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC071C12|TrEMBL
MTTVHPALSFELFPPRSQASCESLLRTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQDGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSNAE
LHRIGVEYALNQCRTVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEY
A
>A0A1G1JDD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica bacterium GWA2_52_8|TrEMBL
MRMKDLYSRPQKTVSFEFFPPKTPETELKLLETIQELKPLAPSFISVTYGAMGTTRDNTI
RLVERIKHQEGIEAAAHLTCAGHTKDEIALILAELKAKGIENLVALRGDPPKGETEFKPA
ANGFAYASELVQYIRQDHEWGPAFSIAVAGYPEGHVECRNKREGLQHLKIKVAAGADVII
TQLFFDNRDFLDFVADVRALGIKIPVIPGIMPVTHGSQIQKFAAMCGAKIPLEIQQAISR
FGADQASIEAFGIDYASHQCAELLRAEVAGFHFYTLNKSKATAAIYRNLNLGQSSK
>Q6LVH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium profundum (strain SS9)|TrEMBL
MGYSHASHLDSLNQNIADINGDINVSFEFFPPSSEKMEETLWHSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLIAAPHLTCIDASRDELRTIARDYWRNGIRDIVALRGD
LPAQGTKPDMYAADLVELLRKEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNMTQAKRFAVANNVKIPGWLEKQYQ
GLDDDLLSRQMLGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAEVEAK
>A0A356LEE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Advenella kashmirensis|TrEMBL
MSSFSDEAFSLEFFPPRDQASRERLVGTAKQLMAMHPRYVSVTFGAGGSTRDGTAETVSM
FSQLGCEAAPHLSCIGASRASLIQLLDQYKAKDIRRIVALRGDLPSGMGGNDSELPYASE
LVRLIREHSGDWFHVEVAAYPETHPQADSPEHDLNNFVTKVNAGANSAITQYFFNADAYF
DFIDRAVQRGVTIPIVPGIMPITNHTQLLRFSQMCGAEVPRWIRLRLAQFGDDKASIRAF
GADVVTQLCQKLIDGGVPGIHFYTLNNAEATLAIWKNLRY
>A0A7J9LCX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium schwendimanii|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGIATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFINDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSLDKL
DALVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A318LUX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella flavalba|TrEMBL
MTSVIERLRGDTPVFSVEFFPPRDEADEAVLWRAIRELEQLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGEWI
PHPEGLGFAEELVDLVRSLGDFCVGVSAFPYGHPRSPDLDTDTRYLVRKFNAGADFGIAQ
LFFEADDFLRLRDRVAAAGCDKLLIPGIMPLTTPRTLHKTIELSGVDAPRALLDRLEPLS
GDAKAFRAEGLDAVTELCERLLAEGVPALHFYTFNRSKATRELVGRLGLVPARA
>A0A813DL37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polarella glacialis|TrEMBL
MTEDALTACRKMGVRNIVALRGDPPRGAEKWTATEGGFNSALDLVKFIREKHGDYFSLSV
AGYPEGHPDNIDVIAGGVAALSPSEARRCRVVKDENGKEIVTVCPDAKFVKEMIYMKEKV
DAGAEFIITQMFLDATVYLDYVVECRKYGIMVPVVPGIMCLNNIGGLVRMTELCKTRVPV
GMMERAEKANTSDDAFKAFGVVEGAAMCKQLLEGGAPGLHFYTLNLEKVVIGTLVELKLI
TAQQAAEFQSGDADAKSMVSAQGISTGTVAGRPVLSGNRSLKEADPTMYQLVLDEKARQI
SCIELIASENFTSRAVMECLGSALTNKYSEGQPGARYYGGNEVIDKVENLCKARALKAFG
LDDKEWGVNVQPYSGSPANFAVYTALLQPHARVMGLDLPSGGHLTHGYYTAKKKISATSI
YFESLPYKVHPVTGLIDFDELRKSALVFRPAMILCGASAYPRIVDFAKFREIADEVGAYL
MADIAHISGLVATGEHPPPFQFCDVVTTTTHKSLRGPRAGMIFFKYSDKVPDMKERIDMA
VFPALQGGPHNHQIGALAAQLLEVDTQAFKDYSKAVKVNANALADALKAKGHKLASDGTD
NHLVLLDLRPLGLTGSKMEKICEAACISLNRNAVHGDVSALSPGGVRIGSPSMTTRGATK
EDFVQIAGFLDRCVRIALKLQTTHGKKLKDFEAAVPSDPEVMALKKEVNEWASKFGYPGL
>J7EPV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nicotiana tomentosiformis|TrEMBL
MKVIEKIQGAAKDENRVVFSFEFFPPKTEDGVENLFERMEGMVAHNPSFCDITWGAGGST
ADLTLEISKRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKINGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDVIPANGIATQEIYENDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQLGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPEEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTLGWDEYPHGRWGNAQN
PSYGALTDYQFMRARSRDKKLQEEWAVALNSVDDIYERFKDYCLGKLRSCPWSELDGLQP
ETKIINEKLGHINTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSGEKL
NTLVEKCKAFPYLTYMAINKEGNWISNISQTDVNAVTWGAFPAKEIVQPTVVDPASFMVW
KDEAFEIWSRGWAQLYPETDPSRKLLEQVQNSYYLVSLVDNDYINGDLFSIFKDI
>A0A1Z2SFQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio gazogenes|TrEMBL
MGYSYAGHIDALNQNISELSGDLNVSFEFFPPSTPQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHTIIKEIKSQTGLVAAPHLTCIDASREELSQIADDYWNNGIKNIVALRGD
IPPGRGKPEMYASDLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKADAGANRA
ITQFFFDVECYLRFRDRCVSAGIEVEIVPGILPVSNFNQASRFAAQNHVKVPGWMSKQFD
GLDNDPVTRQLVGASQAIDMVRILCREGVKDFHFYTLNRAEMTYALCHTLGIRPQA
>M6H7K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Zanoni str. LT2156|TrEMBL
MNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEVEHRP
EEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A1W1J2F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium casei|TrEMBL
MSASAPLDYLELDHAGNPRAAGVGKAPGRTSLSFEVIPPRHDADSAKTENLLQVLGSYNP
DYIAVTSSKRSGWLEGTAKFIAQISSTTSMRPLAHLACTAGDRQQLISWINVLVDAGVRG
FLALRGDLEPGQDKLPEGYLQHADELVRLIRQLEGEQAARFAAGRLAVGVACYPNGHAES
ANADEDFDVILSKQRSGADLAITQLFFDAEDYLKFAQRARLAGTRIPLIPGIMPITSLKR
VQRMGELSGLEVPQRLIEKLSLARSPDEEYAIGMAHTVELARAVLAGGAGCLHIYTHNNA
SITQELLSSIGITPDVKKQP
>Q4Q0B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania major|TrEMBL
MSKLISDAIAAEDASKWNTSYELYPPRSEKAEEDMMKVLVPNFMHQSPVFLDLTWGAGGR
TSGTTMRLCKDLQHAHPDTPINMHITCTNTPKGLIKETLEFAKTHGIRNILALRGDPPSG
EEFQVDPDGFACARDLVRYIRDTYGDYFCVSVAGYPEGHPSRIAENGTISHEDHQKELEY
LKEKVDAGASFIITQLFYDASLYVKFVKRCREVGITVPILAGLLPITTYAGFVRMVSLCK
TSVPSDVKKRVEELKENPDGLKEYGVEQCVQMIECIRASGLDYHHLHFYTLNNSAQIFKI
LKRLNALVE
>A0A841ZDK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEQVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVTEQIISQN
>Q979L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)|TrEMBL
MQSVCAFIFILITQGNKIIRKVYCFALIHSPKMYSSSLKELRFVRSVEIVPSRNQGLEEL
AHSLDSLEGKANALTSPENPRGSPGIDPIITLFFLSKDRNIIPIPHITPRDKNKVHIISQ
INTANKFGINNFFVIGGDPINPKYESHEVREIDPIDLIKLIKANSGSTVGAALNPYRNVE
EEIAWAKKNAGADFFITQAIYSSDALSMDWLKKRNFKLIAGFLPLIRKNQVEFSEKLGIF
LPKVVKEKLLNSEDIRSTSVNIILNVFDEVKDFVDGIHIMPLGHNDIAADILGSI
>A0A5B2VCQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinarimonas soli|TrEMBL
MTSAFRPSRHGARPIRVSFEFFPPKTPEMEATLWASIERLAPLGPSFVSVTYGAGGSTRE
RTHNTLSRLVRETALKPAAHLTCVAATRTEVDEVVRSYWDAGVRHIVALRGDPVAGPGTA
YEAHPGGYEQTCDLVAGIKRVGDFEVSVSAYPEKHPEAASLDADIDALKAKVDAGADRAI
TQFFFDNDLFFRYLDRVRARGIDIPIVPGILPVQNFKQAANFAAKTGASMPAWLAARFEG
LEGDVETRKLIAAAVAAEQVIDLVDRGVTDFHFYTMNRADLVYAICHLLGLRAQASGEPT
RVAA
>U5P5N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus ilei|TrEMBL
MTKQTPSLSFEVFPPNPEVGNAKLLRALENMQELAPHFISVTASNNKYNIKETTVALANH
IQNELSIPTIAHLPAIYLSKEKVADTLHDLDQVGVHRILALRGDIIPGVEPLEDFRYATD
LIEFIKTEAPHFDVIGACYPEGHPDSPSQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVHHATKALFDHQPNLEVI
>A0A150HGP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium laevaniformans|TrEMBL
MSAVTPTPATAASRVAGCPKSMAYGPCGGVNADGTCEVHPTPCVFLTRDLPVRWTSPTTE
ETLSDTVSEDPSRPATPAGRELVEIAARRPLVFTGFPVRALRADAVGTTAEALIGSVDAV
LSGDAGRSRVQFPPSYRATLIGATGLRVWMGFNARDRNRTTLERELLSLRALGVAGVHCV
TGDHTQTGDRPDARPVFDLESTTTLPRAAALGLLTSFAESPAAPPIAERGARVAEKQRAG
GRMCLTQYAGDAEEVAAFVALCRAAGSDVPVLPGVPLVVDREGAELLASFHAAKLPSGFI
DRLFAARDVRAEGIRLAVAYGQALIATGEVGGVVIAGGARPGDEAAYATDLATVARELGG
GS
>A0A497UL78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. 7|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVGQINNLGRGKYLHNEEEACDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A482TPN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium petrolei|TrEMBL
MKVTQHIEAAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKQGGNDFAVDLVKQINQLNCGKYLHDVMDVDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIKQIASKIF
>A0A836C869|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tribonema minus|TrEMBL
MAEHGKLDEKVVDVIAAASEGAFNDAGECVKPLVGLEFFPPRTTQGVDNLRERLQRLKKV
GPVFADFTWGAGGSTADLTLDLTLEAKHAHGLRPNMHLTCTNMPLERIESALRRCREEGV
TNIVALRGDPPAGADHWERSEGGLGCALDLVGYVREHYGDYFCISVAGYPEGHPDRIKVR
EGGVESLSESELTRYSVDAAGQVQVCGDEDWEAELAYLKAKCDAGADVIITQMFFDASVY
GRFVQECRRVGITAPVIPGIMCINAYAGFHRMTGLCKTRVPPELRKRMEAIKDDDAAIKA
FGVEYGEELCRALLKHGAPVLHFYTLNLEKVTVGILRRLGLAGEYEAAPAAEKKLNGTAA
VTNGTAAATNGTAPVPALAV
>A0A1D1ZQH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Auxenochlorella protothecoides|TrEMBL
MNTMMHLTCTNMSIEKLHESLEKAKSMGIRNILALRGDPPKGETSFTAVDGGFACALDLV
KYIRQEYGDYFGICVSGYPETHPDLIVDDPVAMEANYRSDLAYLKAKVEAGADFIITQLF
YDVDCFLAFMRDCRVEGIAVPILPGLMPLMTYGGFKRMTAFCKTRVPAHIAATVEALKDN
DEAIKAYGISLGTLMAQRLLDAGAPGIHMYTLNLEKSAVGILQHVGLVKVEPEAEEAEEP
QRLAATA
>A0A8I0YS23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas juntendi|TrEMBL
MSLLKTALREHHFVCVMEFVPKASAERFAAMQAIMDRAQLCGWPMTVAIGDRVGSPLDMS
PLDALASFDRPVPALPHFSGKDRERHHLLAQLQRMEAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQAAPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMREMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGIHDLKQLLALEARLAYWQTHVHTLEQWAPA
WQASWQMPGLPAVTFHPPQANWRQGESRVDASFKEKARYHLMHGMHGLLFSRRNSLSKAF
GWAVRQPLWTTRLGAQVLHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVGQTAVLRERLIPCIEVQTRHRSSWPQWFAPPSP
RRVSPQPAPRTQPES
>A0A1F5RMV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium RBG_16_71_46|TrEMBL
MPSPILDRLARGPLLADGAMGTLLYERGVPFSESFDGLNLTKPTLVESVHRDYLAAGAEL
IETNTFGTNAIRLAAHGLDDKVRVIARQGAKTARAAREIVGVDAFVAGSIGPLGKPLVPF
GQITTADAERFFHAAAEGLLEGGCDCFILETFQDLNEILAALRSVRRVSLGLPVIAQMTF
GQDGKTLYGHTPTLAVGALKQAGANVVGVNCGVGPQATLEVLEEVLAAAGDTPVSAMPNA
GLPQFMDGRFLYLASPEYFAEFAARAVDLGVRIVGGCCGTTPAHTRAMRERLSSHLPAEK
LAPGAEIRVIEAAPAPVELPLTSEEPVLLKALRQKFVVSVEIDPPRGINTRKVMEGAELM
VRRGVDAINIADSPMARIRMSNMALAYQIHTHFPRIEIILHFTTRDRNLMGLQSDLLGSH
ALGLRNILCLTGDPPSLGDYPNATAVFDTDATGLMRIVRRMNQGTDLAGSSIGAATRFAF
GCGVNPTADDLDHEFERVRRKLEAEPQFVMTQPVFELECWERFVTRLSGLTDIPILIGVL
PLQSFRHAEFLHNEVPGIQVPDWIRERMHAAGSEGQRVGVELARDLLAKCKSMANGVYLM
PSFGRYENCLEVLEGVS
>A0A6G4W6X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium camelthorni|TrEMBL
MNRMAGTSDHAVLARFLGNYSVEVTARDADAAVHRLPPGTEVFIANLPKDSPDMLVAAAA
RLHRAELVPVPHIVARKIRDRREFDDLVGRLADEAGVDRVLALGGDHDRPTGEFDASLQL
IRTGSFERHGIRQIAIGCYPEGHPRIANQVLQDALEAKLAAIAERGLAARLVSQFAFKPE
PVLDFARELRAAGVSAPLRIGVAGPAQRAKLVKYAIRCGVGASLRALTERRQLLGGLLRA
ETPEKLLTAIALAHRDDPSLRFEGAHFFTFGAPEQSIEWANSQIEDGRNAAVQPTINSRH
QGGMSHEES
>A0A1E9G989|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC062H08|TrEMBL
MTTVHPALSFELFPPRSHASCESLIRTIAELEGTNPDYVSVTYSGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDVQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSARLAGVDIPIIPGIMPVTSLKRLRNLCQMAGMSVPADLAYALETATSSAE
LHRIGVDYALNQCRTVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEF
A
>A0A1K1R6M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinomicrobium oceani|TrEMBL
MKVTEHIEQAKGNTLFSFEVVPPPKGGNIQELYNNIDPLMEFKPPFIDVTTSREEYIYIE
REGLLDRKIVRMRPGTVGICASIKHKYQVDTVPHVLCGGFTCEETEYMLVDCHYLGIDNV
MALRGDAMKHQRYFEPTRGGHTYANELVSQIKNITRGKYLHDVVESNNMPDFCIGVAGYP
EKHLEAPSLDYDLKKLQEKIDAGADYIVTQMFFDNSKFFEFVEKAKSMGITVPIIPGIKP
IAVKRHLQLLPQVFKIDLPEELIRAIEQCKDNKEVRQVGIEWCIQQSKELKAAGVPVLHY
YSMGKSDNIKAVASSVF
>A0A659Q0B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Wilhelmsburg|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITHYFYDVESYLRFRDRCVSAGIYVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A518AKJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeoliella mucimassa|TrEMBL
MSLADIYSTDQPGLSFELFPPKTEAGEEALLKHVQRLLEFSPGYITCTYGAGGSTQNKTL
DIIGRVHEMSGLPVATHLTCVGSTAEQLGEYLTEARKRGVDNVVALRGDPPKGEDSFTAV
EGGFKYANELVEYIRRDFSDMGIAVAGYPEKHVEAPSLDVDLENLKRKVDAGADVVVTQL
FYVNDDFFAFRDRCVALGINVPIVPGLLPVTNFAQIKRITSLCGAKLPGEFVSALEAAGD
ESDTQFQVGVDFATQQMAQLLEAGVPGVHLYVLNKSEAASGVLENLGWKAN
>A0A3T0V031|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia alkanivorans|TrEMBL
MRIAIYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFMPPRDAEGEARLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSIAELRALVGAYADQGIA
NILALRGDPPGDPLGEWIAHPEGVEYAEELVHLIDTLGDFHVGVASFPEGHHRAPDLEHD
TRNLVNKLRAGAEYSITQMFFDVEDYLRLRDRVQAADPEQGAKPIIPGIMPVTSLASIKR
MAELSGSVIPPKVVERFTKAAGDGPEEDRATVRAVGIDFATETAERLIAEGAPCLHFCSL
NFAKATSEVLGRLGVDVDAALHVPA
>A0A5N7D6K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus pseudonomiae|TrEMBL
MFPFPLIGGPVKLRPKPFPPRWISPQSSFFNYHPSRTFVGTDSGNKMEKITDKIAALPPD
ANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGSTAQRSLELAEICQRQ
LQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYSMHGEDDSNKDFT
FAVDLVRYIRQKYGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTQAGADFIMTQ
LTYDIEAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVQIPPQILSEL
EAVKHNDDSVKRIGVDIISNLVDGMRDIPCPGIRGFHFYTLNLEKTVSFILERCDLIPPY
SEDFDAIEDGEEISAMDGAQLRSLTRRRASSINSLPHNRVIVDKLHASEVSSKASISHEA
PATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLH
VPPSVAHRIWGFPVSREDISALFRRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELL
QLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLL
QKHGHEKLAWFATNAKGDFESSLPAQTSDADPIEMNPNNVNSVTWGVFRGKEIVTPTIIE
EVSFRAWGDEAFGIWDEWRSIYPRNSATERFLNETKDDVWLVCVVGQDFGAGTDMGSEEE
EDEKKFMWRVLLNAK
>H2ANE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 / NRRL Y-8276)|TrEMBL
MKITEKLQQHQEVCSKPTYSFEYFVPKTTQGVQNLYDRMDKMYQSSLPLFIDITWNAGGG
TLSKLSTELVSTSQSVLGLETCMHLTCTNMEISMIDDALESAYNSGCQNILALRGDPPRD
AVNWQPTEGGFAYAKDLISYIRCKYGDYFDIGVAGYPEGHPEEPNKLKNLKYLKEKVDAG
ANFIVTQMFYDVDNFIQWCKEVREFGIDVPIIPGIMPITGYAAFLRRASWGQINIPKYFF
ALLDPIKDNDELVREIGTKLVVEMCRKLLSSGYINHLHIYTMNLEKASLMILEQLDLLPT
ENEYLTEPISMLPWRKSLNPKRKFEEVRPIFWQRRPYSYVARTSNWAVDEFPNGRFGDSS
SPAFGELDLCGGTLLRQSSKKCLELWSTPESINDLAQLVISYLNGKINCLPWSDMPIDRE
VDALLSHLIQLNIKMIITVNSQPQINGTPSSDKIYGWGPKDGYVYQKEYLEFLLPKTKLP
SLQAKLEKNKILTYFAVDFEDNLVTNHSKDSKANAVTWGIFPGREVLQPTIVEKVSFLAW
KEEFYRILEEWKIHLIENNASDSVNFIQSLLEDYVLVNIVDNNFVSPNDDIFDLLMSL
>S1E723|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli KTE73|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2G5V1N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis nigoni|TrEMBL
MAILRVNGIDSGDENAVVTEKPVFETSKSWSLKNYELLHERIERLIDEKTPFFSLEFFPP
RFVNGVPNFLERVERLSEGGSVFVDMTWHMGSDPANIDKVTSSSSIAASMLDYCGVDTML
HMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPGTELEDTNQFRALDMIRWIREEYG
DYFSIGCAGYPLGHPQAPSYKADLQYLKAKCDAGANFVITQLFFEPETFEKFVADCREIG
ITKPIIPGIMPIMGYESIKRIAKLSQLEIPDHILEDLEPIKHDDDAVQKYGTERCIEMCR
RLLDNGSAPSIHLYTMNREGSIREILKALGLWKLEGDRVFPWKNRSQHPIRCLESVRPIY
WSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTVSLTK
>A0A4U3CJ62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. CCUG 61487|TrEMBL
MTPTVRELLASERPTWSFEFFPPKTPDGEAQLWTALRRLEALRPSFVSVTYGAGGSTREG
TVSVTERIATETTMTPMAHLTAVDHSIAELRHVISRLADAGVRTIMALRGDPPGSDPQAE
WIAHPQGLNYASELVELIKSMGDFSVGVAAFPERHPRSPDFDTDVDMFVAKCRAGADFAV
TQMFFRAEDYLRMRDRVAARGCDVPIVAGIMPVTNAKQIKRIVQLSGQAFPAELAERFEA
LDGESPEAKAAVRAYGVEVATELCRTLLDEGVPGIHFITMNRSTATAEVYANLAGATAVT
PAR
>A0A845SWU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerotruncus colihominis|TrEMBL
MYLYTNDIIHQGGCIVRFDRPYLFDGAFGTYYFSKTGNEAPCELANLTAPQTVLDIHREY
IASGCDALKTNTFAANPVSISDSVRLNEIIAAGWSLAQRAAQESGARVFADIGGICADTA
EMDYLTIVRNFLDLGAHDFLFETLASYQDVRPAVDLIRQSVPDAMVIVSFAVSQDGYSRR
GLYCRTLFDQAESDPCVDAVGLNCSCGPSHMRSLLRALGQRVKPVVAMPNAGYPSSLNGR
VFFEDNADYFAQQLAALYMDGADILGGCCGTTPQHIRRAAAALAAAAARPEGAGWPEPLA
APATGADAPGGGRPGLLHKEIAVELDPPFDYDCSFVLAAASELRACGVDLITVTDSPLSR
TRADSLMTAAKIRREAGIEVMPHISCRDKNHIALRAGLLGAAFEGINRALIVTGDPPMQA
GTRGSDGVYHLSSFDLIAWIHSMNNEVFADAPFLIGGALNVNAVNFGVELARAKKKLSLG
ASMLFTQPIFSDEAVDNFLYARQELKDCRLFAGILPVAGYKNALFLINEVSGIEIPDTVV
RSLEGKTPDEAAAISVAYSAGIMQRVYDAADGFYIMTPLKKVNIVRGLIEEIRRYEQ
>A0A7C4T0W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MRFREKIEAGKFVVTSEVGPPKGADARALLEDAELIRGRVDAINVTDLQSSVMRLGSLAV
SSMLVQKGFEPVYQLTCRDRNRLALQSDLLSAAALGIENILVLTGDHPVMGDHPEAKPVF
DLDSVQLLEAVRGLQEGFDMKGNKLEGNPPRFCVGAVVNPGADPLEPQIARMEIKIASGA
QFFQTQAVYDVKLFERFIEKTKHLKTTILAGIVLLKSAGMARYMNKNVAGVFVPDALVKE
MEDSRDKAAQSVEIAARLIKELKPMCQGIHIMPIGWDKKVPLVLDASGL
>A0A061R353|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetraselmis sp. GSL018|TrEMBL
MRGGIGNAASPTPPAADEIRSSRWLVRTVGVQCRSRRELGEHILRQAFGNDDGDADQIGA
ANALLCVSGSHPVRQLSIMGRLLPSSLDTLAMAGEMKARGNLPGSLRLWAVENPLLEYDA
QRLRRKIEAGAEVVVTQPPLDWDSFQRWADDADRLGLLEQCQLVVGLPMLSSAGNLAFWL
QLCGAHSAPWAQSVLKRWSDEESKGAESFQEWRLQQTVELMQRIGSLPGAAGVHVMPLTK
RAREDALAVIESGAIAPWVVQDD
>B0JQ27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa (strain NIES-843 / IAM M-2473)|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSKSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPVHN
>A0A0A7PWG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida S12|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQVARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQASPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALEARIEHWQTQVQSLEQWAPA
WHASWQMPGLPAVTFHPPQAGWRLGESRVDASLKEKARYHLMHGMHALLFSRRNSLSKAF
GWAVRQPLWGTRVGAHVLHTLERSVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A3A4NI25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MSEGILSEHRFREMLRSRDRFTITAEFTCPAGRKPEKLLQFLAEYESNPPAWNDVEITAV
TVTHNPSGVVTASPSDVYAHVRGAGGTRGLSFIPHVSSKGMNRAEIETFLRGLASHGVRN
CFIITGDKPLVGKSVFDLDSLNLLMLVRKMNADARVTAGLQQPAVDFFTGAGVGLAKYEE
GVCMQQMLKVEKKVRFGGAGYFITNLIYDPRKVEDFFRYLCENEIHIPVIGNVFYLTEPA
ARRMRREKLPGCYISEALYARVAGESRDGWIERCAQLAAMWRDLGAAGVDLGNVEDLGLV
KEIIDRARAIGSGWREKQENLCFPPQNNDNYYLYNNDSPTQPRTPTVPLRRRILNRTHDR
LFEPDSVGYKAMRYLMEHNRGIREGQGFSYESLMLLETILKRVMAKCRSCGDCFLPENFF
VCLMGECTKGLTNVPCEDSTVDGRCGVDESKPCAARLVYDAARFFTGDVEALRKLVNPPK
EADLYHTSSFRSFFLNMDHHHRNPLVIVGELIHTTIPKVKIAFDKIKEEGAIFAPESPGV
QYIQAAIESQVLKGCDYLDCNVDDAGGGNPELAKRLMADTVRLIVEHGQGMPPCVDSSDV
EVLRAGITEYYRTAPQDARPPLVNSANAENLEKFWDLVAIGPFKVIYMLMESSMSAGAGG
QYVTPEQMHENALLFFREAAKRGFRPEQIFFDTTVMPLVVEFACFNRPGYNYCSFEGLRR
IMEDREMKGVGTILGVSNLIRDFPRGRKIGLLRAYVDQAMKRGLTAAIADVDKEYGLKPP
DDEEIVEIVKAFIEYDGTPGAFQRMQDAYAQYRAYGGKD
>A0A3M8FTE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaera sp|TrEMBL
MHMRDMFKRDKATFSFEFFPPKTEQGAANLFKTITDLEPLQPSFVSVTYGAGGSTRELTN
ELVGRIRGETSLNAMPHLTCVCHQRDEIESLLERYAEQGISNILALRGDPPASAQGHRFE
DDAFRYAAQLVAAIQRFNDRGTHINGKGFGVGVAGFPAGHPGTPNRLEEMDHLRAKVDAG
ADFIITQLFFDNHSFLDFRDRCRHAGIDVPIIAGIMPVTSITGMRRMAELALGTHFPAKL
LRALDRTNGDEESVRRVGIHWATQQCADLLDNGIDGIHFYTLNKSSATREIYASLGVQSS
TQLIT
>A0A061S486|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetraselmis sp. GSL018|TrEMBL
MKISEKMNKSIAEGKKFFSFEFFPPRTDEGVDNLFDRMENMVSYGPTFCDITWGAGGSTA
DLTLEIAKRMQNEVCVESMMHLTCTNMPKEKLDEALKTVRAAGLQNILALRGDPPKGQET
FTTVEGGFSCALDLVKYIRETHGDYFGIGVAGYPEAHPDVITDDPEAMEKAYRSDLDYLK
KKIDAGGELIITQLFYDCDKFIKFVADCREMGITVPIIPGIMPIMTYGGFKRMTGFCKTY
VPQEILDTLEPIKDNEQAVKNYGIHIGTEMCKKLLDAGTPGLHMYTLNLDNAAVSILKNL
GFVNPDVLPRSLPWRPSANVVRGPQEGVRPIFWSNRRLSYLARTSGWDSYPSGRWGSQAR
GKGGPFNPVPEQFMKKAVSSEKRREKALEAWGTVGGVKDVEEVFAKFVKGDVKMLPWSEF
DKLQGETSEIADKLADINRKGFLTINSQPRANGIPSTDPKLGWGGPDGVVYQKAYLEFFC
SPDAFKGLLEKIAAAPSLSYQAINGKGEYKSNLGEDAIVAMTWGVFPNKEIVQPTIVDCP
SFKVWKDEAFDLWTTSWASLYEAGSQSAKTLSEIKDTYYLVSLIDNNFVNGDIFKVFA
>A0A1Y1Z223|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clohesyomyces aquaticus|TrEMBL
MEKVTDKINALPEGANYFSLEFFPPKTSMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRSLIDEALEQAKVLGIRNILALRGDAPRSEE
YRDEAQMAGGDSNKDFTWAVDLVRYIRKQYGDYFCIGVATYPEGHSDASSEYPEHQDPLF
DLPYLVEKTKAGADFLMTQLFFDVEAFDKFEKMLREHESGVFKTIPIIPGLMPIQSYQIL
RRTTKLSHAKLPSDILQRLDAVRTDDQLVKEVGVEILCELVEHIKKRPSPARRGFHFYSL
NLEKAVSHIVENTHLILQTLVDDDEAVVELGPGTLSPPDGALTNRNRSRLSSMNSSPHNR
VIISRPSRSSNMSFEAREEEAAIPNGPINTRATTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTAQALKLWGHPVDKGDISALFRRHITGDLNALPWSEQGLSP
ETSTIQAELLALNNKGWWSVASQPAVNGLKSSDPIFGWGPHNGFVFQKPFVEFFLPLSDW
EKLQPRLEAEEQITYFAGNSEGELVGNSEGSVNPVTWGTFPGKEIITPTIIERESFASWR
DEAFSIWREWQRVYPTKSVTAKVLGEVRKDVWLVNVIWGDFVQGAGLWEFLMKE
>A0A2A3MJW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas abyssi|TrEMBL
MTINKTVPVNFEFFPPKTEAGQAKLIAVANVLAGEQPEFFSVTYGAGGSTRDGTRRTVLQ
LNNEVGVPAAPHLSCVGDSREDLRTLLNDYRDCGIQRIVALRGDLPSGMGHASGELRYAN
ELVEFIRAETGDHFKLEVAAYPESHPQAPSFEADLKNFIRKAKAGADSAITQYFFNADCY
FHFVDRVRKAGVDIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLESYGDDSDSIKA
FGTEVISQLCERLVEGGAPGLHFYTLNQAEPTVAVLRNLRG
>K7FMT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelodiscus sinensis|TrEMBL
MMVTEPPCVSNGSASSRSDGGSSSGSESSKDSSRCSTPILDAERHERLREKMRRRHDSGD
KWFSLEFFPPRTANGAVNLISRFDRMGMGGPLFIDVTWHPAGDPGSDKETSSMIIANTAV
NYCGLETILHMTCCNQTKEEITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVD
LVKHIRCEFDDYFDICVAGYPKGHPEAESYEADLRHLREKVSAGADFIITQLFFRSETFL
TFMKDCQAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKEVIEPIKDNDAAIRNY
GVELAVSMCRELLDSGMVPGLHFYTLNREVATTEILKRLGIWKEDPRRPLPWAVSAHPKR
RVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREEL
LKMWGEELTSEESVFEVFTCYISGEPNREGHKVTCLPWNDDPLAAETNLLKEQLEKVNRR
GILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSENITALLKVLKMKKYELR
VNYHIVNVRGENIANSPDLQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQW
AKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVMEDTFELLNCPTEQ
>A0A654DRK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacterales bacterium 8AC|TrEMBL
MSFFHANQREALNQSLAELSGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLDAAPHLTCIDASPAQLRDIAADYWNSGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPSWMTSMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAIA
>A0A0S7XPS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacter sp. DG_60|TrEMBL
MVKRIRDILNEKELTYSIEFFPPKTKKGNDNLFETARMFKELEPDWFAVTYGAGGSTREL
TMDIVDELQKRFEIPTMHHLTCIGHSKAELRTIIEEMKRRGICNILALRGDPPKDIDHWE
PPADGLDYAYQLCKLIRSYDSFFSIGVAGFPEGHITCPDKETDSKYLKIKIDAGGEFVIT
QIFFDNKDYFEYLERTKKIDITVRIIPGILPITNYQTLVKFCKTCGATISQRVHDIFKPL
DGNDEATYNAGVQFTVEQCSELLEGGAPGLHFFALNKLDPTREILNRIKR
>A0A1I7G882|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium pyruvativorans|TrEMBL
MNRIKQWIEQGPLLVDGGMGTYFSSKEHLPGSGCEMASIEKPVLISAIHREYLEAGARVI
KTNTFAANRPTYRHTETVRRIIRASWNLAVRAAAPFGAEVFADIGPVTGLPPAAAAREYR
FIVEEFLSLGAENFLFETNADDTGLDEAAAYIRSKAEDPFLAASFAVLPDGYTRSGIFGE
DLIRDLTARGNFDAVGFNCVSGVRQMARLLEDMDLEGVTLSIMPNAGYPTVVGNRTFYDS
DPVYFGRGLAEIAARGASIIGGCCGTTPAHIAAAREELTKKSRDLRSAPGRSRSEALAAG
EEEDRVPESPFFEKLRAGEMPVAVELDPPETADVRKYMDGAARLAAAGCDLLTIADCPVA
RARMDSTLLACRVKRDLGMETIPHLTCRDRNLNATKALLLGLSAEGLRNVLVITGDPIPT
AERDEVKSVYQFNSRKMAAFIRGLGRKSFPVPFHVFGALNLNARNFDVELRIAREKVEAG
MVGFFTQPVLSRRALENLKQARRTLQPAGAYIIGGIIPVVSQRNALFMENEINGIHVSQE
IIRRYEGLDRDAAEALALELSVKIARDMAPFIDGYYLMTPFGRTKLMARIIAGIRG
>A0A8D4U7H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWNSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A533YN21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MKKPFRDRVKEGPIVGDGAMGTLLDLYGFVELPHELRNIKNPDVVERVHREYIAAGSEII
ETNTFSANRLRLTQFHLQTSLRDINLRGVEIARQAAGESVYVAGSVGPTGMLLEPIGKIK
RQKAKDAFKEQIELLIQGGVDLIMLETFVSLQELDDALEVAKSLTDLPIVAQKAFAEDGS
ILSGSFPIDVINHLIDQGADVVGANCTVGPQRMFSIIRNVHKDGVILSAQPAAGIPTLLN
GRSIYHTTPAYLASYARELVESGVTLIGACCGSTPEHIRAIAETVKGLKVGHSLPRAEAK
SREKSTTEPEPKYYVEASRWSRFSRNVGKKFMTTVELVDAVNITEGARARLRMSSIAISF
QIQQRVGIEAMCHRASRDHNLIGLQAELLGAYTIGIRNVLCITGDPAGIGDYPQASSVFD
VDAVGLIRAVHSMNQGIDIMGNSIGEPTSFYIACAANPSADDLDAEIVKLEKKAEAGADI
FFTQPIFEMKTLEEFLRRTQHLKIPVMLGIIPLRSFKHADFLHNEVPGMRIPDKLRETMR
SAGSEAAKVGVRLSMDFIKEAKSCVAGLYMMPPFQKYHIVDDLLSVL
>A0A8E1UK13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISIAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A1RV95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)|TrEMBL
MEIIAEITPLRDRDKVLRKLESIKPYVEKVDIPESPGGKPTAHSLAVGALAKQLGLEPIV
HIRLLDVNKTGFKSLLGGAYILGVRYVVVLQGDPPAEGEPVGEVTTEEAVAEAKKMGFVT
GALLSFRRDYIERIRRLGADFYLALHLTDVKQLEGLPPIIYPYIMIKTGNNIALLERLRQ
TAVELPQALGLIEKLRGVVPGIVLSVPGDFETLLQILRKIKTCRS
>A0A7R7B0T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 113-3-9|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILNETSLTPAAHMTCVDAARNQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>V8BD57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis CC87K|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQPNFEVN
>A0A317EDT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zavarzinia aquatilis|TrEMBL
MTLDPIGPLNVSFEFFPPKTPEMEEALWRTVRRLEPLNPAFVSVTYGAGGSTRERTHATV
KRLVEETRLKPAAHLTCVAATREEVDAVARDYWDAGVRHIVALRGDSQVPGAPYQPHPGG
YDYAVDLVAGLKKIADFEISVAAYPEVHPDATSAEADLDNLKRKIDAGATRAITQFFFDN
DVYFRFLDRVLAAGITVPVLPGIIPVSNFRQIVKFAAATGATIPASMARHFEGLDDDPET
RKLVAVTVAAEQVRGLAAAGVKDFHFYTLNRADLCFALCHLLGLRAA
>A0A2N2G296|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-24|TrEMBL
MDGVIVYDIQDETERTHEERPFEFIHTVDPSLYSRHYLKELSVPRVVYRCVGNYIEEAFV
EWLKDGEDQFTVFVGTAATHQEVGLKLEEAYKLRRQYNENMLLGAVTIPERHRLLGDEDE
RVGFKMSKGCSFFVSQAVYDLEASKKFLLDYKQYCLKHEIDMVPIIFTLTPCGSAKTLKF
IKWLGISVPSWLENTLLSSEEMLSKSIQLITLIYKELTKIAKAEGIPIGCNIESVSIRKE
EIEASILLAKEITTFVKYQK
>A0A520JQL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGLSFEFFPPKSEKMETQLWEAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKDEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPVAKVAAA
>A0A507DPL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Powellomyces hirtus|TrEMBL
MKITQKIEKALAEERCFWSFEYFPPKTEAGVINLYDRMERMYQLGPEFIDVTWNAGGSSS
DVTMQVCTTAQSVYGLETCMHLTCTNMPREKIDIALKDAKAAGIQNILALRGDPPRGQEN
WTKCETGFSYAEDLVKYIREEYGDYFCIGVAGYPEGHTENQDPEHDMKHLKNKVDAGADY
IVTQLFYDVDIFLKWHEECRKVGITIPILPGIMPIQNFGGFKRMTSLCKTYVPDSIYAAL
EPIKEDDKAVKDYGVQLAVDMCNQMKAAGIRGFHFYTLNLERSTRLILEGLEFIAPIPQV
RPLPWNPSLAKNREKENVRPIFWKNRTKSYILRTEAWDDFPNGRWGDARSPAFGEIDGYG
FNLKYPAEECLQLWNHPETLQEVFTLFAKYCTNELNVLPWSDAPLFPESDIIRSKLASIN
SKGFLTINSQPAVDGALSSHPVYGWGPKNGFVYQKSYLEFFVSPQALETVVKRIAACPYV
TYYAVNKQGDLRTNTQGDSPNAVTWGVFPGQEIIQPTIVDSASFMAWKDEAFELWNKWAL
LYEASTPSRKVIQEISDTWFLMNVVDNNYKEEQAIFEIFGDASETELASR
>A0A435SCM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.007.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A2T2YIW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adhaeribacter arboris|TrEMBL
MKVTEHIANAKKTLFSFEILPPVKGTSIQSIYNGIDPLMEFNPPFINVTYHREEYVFKER
GNGLLEKISIRKRPGTVGICSAIMHKYEVDAVPHIICGGFSKEETENALMDLNFLGIDNV
LVLRGDSIKTETQFRPHPDGHAYASDLLKQICDLNNGNYLDEDIANPVPTNFCAGVAGYP
EKHSEAPNLETDLKYLKMKVDMGAQYIITQMFFDNKKYFDFVKACREYGINVPIIPGIKP
LTAKNQLRMLPNLFHIDIPNDLVQAIDSAQTPQAVRQAGIEWAIQQCKELVEFGVPCLHF
YTMSKSEATAAIAKEIF
>A0A4Q4R6R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria arborescens|TrEMBL
MERITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCIGVAAYPEGHSDQSHPQHQDPQFDL
PYLIEKTKAGADFIMTQLFYDVEAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTTLSHAKLPSDMLARLDAVKSDDELVKQEGVKIMDEMVEHIKARPDTCRRGFHFYTLNL
EKAVSHIVEDTHLIPSTIDDNDDVIVETTPAINLEPPPNGFVPHRRRSSAVNSGPRNRVI
ISHSSAAKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKDDISKLFRRHIEGDLEAIPWSEQSLSP
ETLTISKQLLALNAKGWWTVASQPAVNGVKSTDPVFGWGPKNGYVFQKPFVEFFIPASEF
AALKPKLDAHEQVTYFAGNAAGEFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIFQEWQRIYPPRSASSTLLGALRRDYWLVNVIWGDFVQGEGLWEFLEQ
>A0A520HWP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
VAAELSRRLYAGGVKQLHFYTLNRAELAFAICHLLGVRAKPAQAAVAA
>A0A415IGE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AF39-11AC|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYDTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNRYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESAFTPEGDGYHHATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELACEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A1F8NAI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_60_13|TrEMBL
TNIDKMCHHIDILKDLVDGINVTDHQSSVMRFPSIGGCLHVKEKGGEPILQMTCRDRNQM
ALQGDLLLAYTRGIRNVLCLTGDSIVVGDHKHAADVFEFDSAQLLRAVRHMETGKDMGGN
DLDGGVQFCAGAIVTPEAKPFEPQFIKFEKKVEAGAEFFQTQAVYDLDNFGKFMDRARQF
PVKILAGIVLLVSARMAKYMTENVPGIFVPKNLIDELAAAPKGEALNKGIEIAGRMIAEL
KKNSICDGVHIMAIGKEEVVPDILAAAGLTSGSTAHTPKSKPLHAS
>A0A853VGW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LCM 4577|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDTVIREFADMGVKRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLFERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A6G6YZ55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. 6(2017)|TrEMBL
MTETISSVPNGYRASKTPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTISRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAAIKKRHADIEISVSAYPEKHPEAADFDADIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQGRNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A5B6TH28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rufibacter hautae|TrEMBL
MKVTEHLQNATSTLFSFEILPPVKGTSIQSIYQGIDPLMEFKPPFINVTYHREEYVFKER
ENGLLEKITIRKRPGTVGICSAIMNKYHVDAVPHIICGGFSREETENALMDLNFLGIDNV
LLLRGDAVKTEPGFRPHKDGHSYATDLIKQVVQLNHGHYLDEEMENPVPTDFCIGVAGYP
EKHMEAPNLSADLKYLKQKVDLGANYIITQMFFDNQKFFEFVNACRAAGITVPIIPGLKT
LTTRNQLNVLPRYFNIDLPEDLVNAVEACTNPKDVKQVGIDWTIQQCKELMDFGVPCLHF
YTMSKSDATVAVAKAIF
>G3T6N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loxodonta africana|TrEMBL
MDHLKARALPARHCCPSLGTRAWVSGSGRFSVPPSTSRSLAMVNEARGNGGPGSRSEGSS
SGSESSKDSSRCSTPGLDPERHDRLGEKMRRRMDSGDKWFSLEFFPPRTIQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETVLHMTCCHQSPEEITG
HLHKAKRLGLKNIMALRGDPVGERWEEEEGGFNCALDLVKHIRSEFGDYFDVCVAGYPKG
HPEARSFEADLKYLKEKVSAGADFIITQLFFEADTFFRFVKACTEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQAIKDVIEPIKDNDAAIRNYGIELAVNLCQELLAGGLVPGLHF
YTLNREVATIEVLKRLGMWIEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTNEESVFEVFAHYLS
GELNRNGCKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKRYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSRMIIQYIHDNYFLVN
LVDNDFPLDNCLWQVVEDTFELLNRPAP
>A0A403FCZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enteritidis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATGDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDIYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1F4EU13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_67_28|TrEMBL
MTRNGRVFSFEFFPPRTPEGKEKLRATWQQLARLGPRFFSVTFGAGGSTREGTLETVLEI
RAAGFEAAPHISCVASTRADVAAQLERYRAQGIRHLVALRGDLPSGVAATGEYRYANELV
EFIRASTGDWFRIEVACYPEFHPQTRNAADEVRNFKRKVDAGADGAITQYFYNPDAYFRF
VDECRAAGIALPIVPGIMPIGNFSQLARFSDACGAEIPRWMRFKLESYRDDGASIRAFGL
DVVTALCEKLLAAGAPGLHFYTLNQAALTATIWQRLGI
>Q39KN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVV
>A0A358Y625|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVIDHISNAKGATLFSFEILPPLKGKSIQSIYDGIDPLMEFKPKFINVTYHREEYIYKE
REHGLLEKIAVRKRPGTVGICAAIMNKYDVDAVPHLICGGFSREETENALIDLQFLGIDN
VLALRGDPIKTESTFRSEPGGHKFAVELIQQITEMNQGKYMMDDIQMEPTNFCIGAAGYP
EKHFEAMNLEFDLQNLKAKVDAGAEYIVTQMFFDNSKYFAFVEACRKVGINIPIIPGLKP
IKTLSHISFLPKFFHIDYPIELANELLKCKDNKAAEQVGIEWGIQQSKELKAAGVPCIHY
YTMSNSSSVKTISKEIF
>A0A1C4Q0Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DvalAA-43|TrEMBL
MRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKA
TEQIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVKHP
QGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDKCRAGADYAITQMFF
NPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFAQLSNASFPSSLKERILAAKDDP
AAVRSIGIDFATQFCARLRSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A0R2NZJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium BACL2 MAG-120802-bin41|TrEMBL
MNSAPTFSVEFFPPKDQAGEERLWSALKALEVYKPDFVSVTYGAGGSTRDRTIRITSEIT
ARSGLSTIAHLTCVGSSRDELIEILSQYKVSGIKSILALRGDPKGGPGVKWESTAGGFDY
ADQLVLLASSMGFEVGVAAFPDGHPASKGNFEQDIKVLLEKERCGASFATTQFFFDVKGY
INLVNQIRAKGSKLDIYPGILPITNFAQLKKMSELAGSAIPIEIQRRVEAAGDSPEEVVK
VGIDIASELSKDLLDYGVPGLHFYTMNSAAPTIEIIRRIGLR
>A0A543HXR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Humibacillus xanthopallidus|TrEMBL
MTRAERFTRSIPDLIGGPLPSFSFEFFPPKDDASEAQLWDAIRRLEKVAPSFVSITYGAG
GGTRDRTVRLTQRVLEETSLTPMAHLTCVGHSVGELRSVVGAYAAGGVRNILALRGDPQG
GLGQPWVAHPQGLDHADELVRLVKGLGDFTVGVAAFPDGHPESRDISEDAETLIRKEQAG
AEFAITQMVFDVDHYLRLRDELTRRGSRLPVVPAIMPITNARQVVRMAELAGQPMPAAVT
DRLERHGDDAAAVRAEGMAIASESSRRLLDEGAPGIHFITMNRSSATLEVFGNL
>A0A2D8IS88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haliea sp|TrEMBL
MTAISFEYFPPKTPEGRSKLLESTTPALQALDPAFFSVTYGAGGSTRDNTFGVVKALREQ
GLDVAPHLSFGADDAESMAALLERYRELGVTRLVALRGDIPSGMGGSGQLVYASELVAFV
RERTGDHFHIEVAAYPEIHPQAESYQKDLHYLKAKLDAGANSAITQYFYNVEAYFYFLDQ
CAAIGIDKPIHAGIMPITNFNNLARFSRNCGAEIPRWICKRIEGYGDDQESIRKFGIEVV
TQLCQTLVDNGAPGIHFYTMNQVEPTREIYRNLGL
>A0A2W5HA67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia acidovorans|TrEMBL
MSFPISFEFFPTKTPEGATKHVQVRKNLYARKPQFCSVTYGAGGSTQTGTFAMVRDIQNE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPQSDLDAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A6M5Z553|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frigoriglobus tundricola|TrEMBL
MPLRDTSSRRPTTVSGEFFPPETDEASGDLFRTVAALLPSFLLVTHGAAARTRDRAPDLG
VRIEGDTNLTPLSHLTCVCHMFSGVRSEAQGQSVVWLVVRANGPHRGAERGRLCRPSASE
RTVSGPRSRTVDATR
>A0A7Y3SN99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium indigoferae|TrEMBL
MVLKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSQLQDWDPDFVSVTYGAGGTTKAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPTFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGISRRETKSAGAAA
>A0A7X8L3F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKKNNQIKLVDHLAEVSCPILMDGAMGTYFHQLTGHSADACEESNLRAPALIKSIHRDYL
EAGSRILRTNTYAWLEYLERFDLSQTEAMIRSASAVATEAVDEYVAERLAGVDSIPPQTA
KSFYILADLGYLPEGFDEQIYKEFCYTIDLWIELGATHFICETLQDDRHLLEVVSYIKEK
LPNSCIMASFAIPPDGITATGETIDVMFSRLDEYPELDILGLNCVSGPVPTTRLLSRIGP
LRKKLSICPNAGYPTVIDRQMVFPTTPTYFGEQMRGVLGLGANLVGGCCGTTPLHIKELS
QVVAAFCQKKEQKEVGSITKDGGIQQTDEGADNQATAKGESRYGDKSLRVTISDLQHTNG
LTTVQPIDHNPILQRMTQGQKLIAVEYDSPATPDIQAYFAGALAIEAAGADALTIADCPV
ARPRGDSSITATALKNVLTSCEPIPHLTCRDRNANATKAILLGLNMVDIYNVLIVTGDPI
PQEDRDDIKGVFNFNSVVLGEYIRTLNETLFERPFNVAGAFNINAMKLTYELRRARRKID
AGIKTLYTQPVMSRQGVERMAQVRQELPDAYIMGGIMPIVSHRNALYMQNELSGMHIDDD
VVARYEGKNRAQGEAIALDLTVRFAEQIRPYVDGFYLITPFNRVHLVCSILSEIKHL
>A0A369XBM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parageobacillus thermoglucosidasius|TrEMBL
MGLLQDLKERILIADGAMGTLLYSHGVDRCFEELNLSKPEDILHIHEAYIAAGAEVIQTN
TYGANYVKLARYGLEDEVPSINRAAVRLAKQAAKHKAYVLGTIGGLRSINKSAVSIDEIK
RTFREQLFVLLNEDIDGLLLETYYDLEELKTVLAIARKETDKPIIAHVSLHEVGVLQDGT
PLAEALAQLEQLGADVVGLNCRLGPYYMIRSLEEVPLPDHAFLSAYPNASLPDYRDGRLV
YETNTDYFKETALAFREQGVRLIGGCCGTTPKHIEAMASALVDRTPITEKAVKQRHVSIS
IQTNEPNAAPPLQDIVRERRSVIVELDPPKKLGIGKFLEGAKALKAANIDALTLADNSLA
TPRISNVALGTIIKEQLGVRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVER
LEKKIQCGAHYFITQPLYSEQKIEEVYEATKHLQTPIYIGIMPLVSARNADFLHHEVPGI
TLSDEIRARMAACANDPVQSAREGIAIAKSLIDAAFELFNGIYLITPFLRYEMTVELVRY
IHEKEQAAQEREVLHG
>A0A7X6Y4D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MEAKTGTKAASHLQKVLEAGHFSVTAEIGPPMSANADFVRNKARELLGLVDAANITDNQT
AVVRMSSIAAAYLVQQEGLEAVVQMTCRDRNRIAIQSDLLGAYALGLKNVLCLSGDHQSF
GNHPESKNVYDIDSIQLINALRGMKEEKVFINGKSIKTPPEFFIGATANPFADPEELQFI
RFVKKIRAGARFIQTQAIYDVERFARWMEKVRKEGLHEKAFILAGILVNKSLKSIEMTKM
VAGMAVPDIFIERMARAASQEEEGVKIALELIDEIRKIEGVKGIHIMAVGWESIVPVIIE
RAGFLPRPAV
>A0A7X8W972|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MTLPLLFDGAMGTYYPEVSNKPLPECEMANIFDKDTILKIHREYIAAGAKAIKTNTFQAN
KISLSSEFKVVEEVIESGIKIARQAVSDKHVLIFGNIGQMGPQEITSFDDYREIVDVFLN
NDITNFIFETYSSIDYLKDLSQYIKSKEKDSFIITSFAIEADGQTRMGEWGENLLREASS
CQYIDAVGFNCVSGPLRIKEYLGKIEIPDSILSIMPNAGYPTVINSRTFYPNNKEYFANA
IMKMMDYGAEIIGGCCGTTPEYIEAIAAILPDYAKKERIKKGKKSVRLDTPYEENLFRNK
LENKKKPIAVEFDPPHDLNISKYMENAKKLGLAGADAITIADCPVGRARIDASLVAYKIK
NELGIESIVHMTCRDRNINATKALLLGLNVENILNIIVVTGDPVPTAERDEVKSVFQFNS
VKLASFIKDLNEDLFTNPMNIGGALNVNAINFKAELNRAKRKEEAGINTFYTQPVISESA
VENIKIAKQELNSYIMGGIFLIVSYKNAMFMESEISGIHIAPHIIDLYKDKTKEECHRLA
VDIAYDFMRKIEDYIDGYYINTPFSRVDIVSELIDRIKS
>A0A840ATF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kaistia hirudinis|TrEMBL
MTEAGGRASRNGGGANGLGVSFEFFPPKTEAMEQTLWTSIERLAPLSPSFVSVTYGAGGS
TRERTHATLARILSETTLNPAAHLTCVGATSAEVDAVVDDYAATGVRHIVALRGDPVEGI
GATYRPHPGGYAYSADLVAAIRARHPEVEVSVSAYVERHPESPDWSTEIDNLKRKVDAGA
NRAITQFFFDNDLYSAFLDRVAAAGLSIPIVPGIVPVLNFTQTAKFAQKAGASVPPWFAA
RFEGLEDDPSTRQLVAAAVCAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGMRSAKP
APASGEAVAA
>A0A6N2CJZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceicoccaceae bacterium|TrEMBL
MTKISLQQRLASAEPLFSIEFFPPKSDAAAEQLLSTAADLQAYAPDFVSITYGAGGSTRS
RTLKYARQLAQDYHYTVMPHLTCVGHSREDLQGIIQEFKKAGLNQIMALRGDPPKGEADF
KAHPAGLHYANELVELIRDNFAECTIGVGGYPEKHPEAPSLEVDLLKLKRKVDAGAHFVT
TQLFFDNSRYFAFVEAARAIGIQVPILPGLMTPTTLPQARRFCQMGDSFLPPELASALEA
VGEDSAKGTRIGLEWSFQQARELLEKGAPGLHFYILNRTNPTAALLDRLKLAGFYQS
>A0A8J6ZFE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Quinella sp. 1Q7|TrEMBL
MGRIAVEIIPRDEAGLRADIDVIKKYPQVDCVNIPDLMSFELRPWQAAEFTQPALPTIPH
VRAMDIDLAKPLPMRDDFIRFGIREVLIIAGDPPKDLTRTVYPTETIDVIRKFRDELPDV
KVYAGIDQYRSGIRDELYRVERKAQAGAVGFFTQPFFDMRYLEMFADLLDGHEIYWGVSP
VLSSRSRGYWERKDKAVFPKNFLPTMDWNIAFAKQVIDFIKTSSGGLYFMPITIDIADLL
PKVFD
>A0A6I6RF47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. GF20|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVTAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A7V6IND0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKHNQITDNALVLYDGAMGTYYRWLYREDYSLLEAVNLSDPDRIKQIHHAYIKAGATRIK
TNTFAAFPQMLEKSADQVKQMVLAAWHLANEAIYELKAQDTVKAVADIGPYFVLQSGLTD
NLRAQNEQAYLDLAKIFIDVGVEEFLFETQEQLTDLIPAIKLIKSYNPNAKITVSFSVNQ
NGFTRIGLGLRELLTQAEKMDEITFTGLNCTLGPTQLSQVFAEYSQFSKFCFFGPNSGLP
ERDLGRGRGGAEAKYFAESCQRAWDNGAYQLGGCCGTNPLDIRALADLFKNQKPLIMKKF
DTKSELTVFEQPGFKADISEKPESGKEAIKSIEVSEKSWYERLLTGEQIVAIEYDAPTKA
NVKTYLEKIVQLKDAGMDLMTIADNPNGQTRIDSALMASRIKQELGVEVLPHFTCRDRNL
FAIHSLLLGLATCGVHQVLAVTGDPIPLEDRNQIKSVFNVNSQSLLRYISQLNLELAQPF
ILCAALNVNAPNFDAELKKAKRKVKSGAQVFLTQPIFTKRGKENLMLAKQELGDKAKFLT
GIMPLVSQKNALFMKYEMSGIDVPDRIIERYANLDREQSEKLALEISRDIMTDLSNVTDG
FYLITPFQRTHLTAQLCQEWKSAKAP
>A0A2I2KZH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia canadensis|TrEMBL
MEAALTEQAVARNEIGSASRGTSTNGFELICEIEPPTRPDLTHARHQIGVLAPVADAFLI
PDNHLGRATVSSIAVAHEVQAMGGHSIACVNSRDRNLLGFRRDLLTAAAYGVGEFLFVQG
DKPTAGNRTGDLTVRAMIEEVRAVADDPVYAGRPPFRVGTAAGLRALPAWKHAADFVFVQ
VSYSVDALLRWRDTHPIDRPVYAGVMVLASAGMARRLATTIPDIDIPTDLVERVERDQAA
GVDAACEQILRLRDSAAFAGVHLVPVSRYRQVAAHLEGLL
>A0A285DY61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. OK270|TrEMBL
MTQTPSIVDRIGSSGGRIPFSVEFSPPRDADAEARLWRAVREFEQMQPAFVSMTYGAGGS
TRDRTVRVTGALAEETTLLPVAHLTAVGHSVDELRAMVGAYADRGISNILVLRGDPPGDP
LGEWVRHPDGVEYAEELVRLVRDLGDFHVGVASFPEGHFRAPDLDHDTRYLVSKLRAGAE
YSITQMFFDVDDYLRLRDRVSRYDAEQGAKPIIPEIMPITSLRSVKRMVELSGSRLPREL
AERLDRAAGHGSEENRAAVREIGIELATEMSERLIAEGAPCLHFITLNFARATREVLARL
GLATSVR
>A0A125PJ51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodotorula sp. JG-1b|TrEMBL
MTSTPELRSTFVSQKVTDKIAALPDDQPYYTFECFPPKTESGLVNLIDRIDRMSALNPLW
MHVTWGAGGSTQERSLELAGASQGMGLETCLHLTCTNLEQGVLEKTLERAKAAGIVNLLA
LRGDPPRGEEYWTAASDDFQHATDLVRFVRAKYGDTFAIGVAGYPEGHADSSDKQADIDY
LFEKQEAGADFVITQLFYDVDVFLQWHKRCRERGITIPIIPGIMPIQNYLSFRRMTNLCG
THIPPNILADLERIQHDDAAVKTYGVELSVKMMRQLFENGIRGFHLCTLNLEKSVTRVLE
ALKWVEPAETRVRTSRQRVRLSIGTFVVNSLRPAPATGASVAGPDIARKDSPASWDEFPN
GRFGDARSPAYGEMDGYGVSLKLPPAEALRQWGQPTQLADVSRVFSSYLRGELPSNPWSE
EPLRAETDMIAAHLIEMNDKRHWWTVGSQPAVDGAPSADAVHGFGPKGGYVYQKAFVEFF
LTREELDELERVSAREERERREKGEGDDGLVKWYAGNRAGDFRSNMGHGDVNAVTWGVFG
AKEIVTTTLIEEMSFRAWCEEAFALWNEWSLLYPAKSEARTFLRFLADSRWLVSVVHHDY
KDRDALWQWLMRLQPAASEGVDVEGR
>A0A3D2NX60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKIKELFNKSPVISLEIFPPKPEASIDTVLNTIDALSDLKPDFISVTYGAGGSSKSHTVQ
IADIIKNKYGIEALAHLTCISSTKKEVEDILTRLRSSSIENVLALRGDRPQNDTCISEEA
QYEYARDLIAHIRNFGGFSIGAACYPEVHIEAGDSLSDLRSLKAKVKSGADFLITQLFLD
NNFFYDFKEKLDLIEVNIPVSAGIMPVINKKQIERITGLCGASIPAKFKRILDKYENNPE
ALKEAGIAYATEQIIDLLSSGVDGIHLYTMNKPEVARKIIGQISNIRSYLGNNIKYA
>B6QFH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)|TrEMBL
MEKITEKIAALPPDSNYFSLEFFPPKTQMGSVNLQARLERMAQALRPLFVTVTWGAGGTT
AAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIRNILALRGDPPRSEE
YNMDGDDDSNKDFTWAIDLVRYIRKIYGNYFCIGVAAYPEGHPGESQTDIQDPEKDLPYL
VEKVQAGADFIMTQLTYDFEAYQKFEDRLRNHPSGAMKTIPIIPGLMPIHGYKILTRVTK
LSAAHIPPAIMSRIEQVRSDDERVKQVGVDIVSEIANQIKALPNPGQRGYHFYTLNLEKS
VTLILESCDLIPPCNDDSAVEDGFAIEQVGSNNQDLKTLVSRRRASSINSGPHNRVIVDK
LHVPTDQQSEHSSRKSITYETLASNAGVPALNPPPRSTQLQISEGIGSLGREATWDDFPN
GRWGDSRSPAFGEIDGYGPSLHVNATVAKELWGFPVTREDIGTLFRKHVSGELYIVPWSE
GGAAEDANLNAETQIIKPQLLQIIEKKNWWTLASQPAVNGVRSDHPVFGWGPPGEGFVFQ
KAFVEFFCPNADYQNKVKPTLLKHGSEEFSWFAINATGHLESSFLLSASSSPKPEDASST
IAADEEPVEVRESKGMAVTWGAFRGREITTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRG
SATERLLNETKNDAWLLCVIGHRYGAGTEPGSEEEKAEMNTLWNVLAGDM
>A0A015JXC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus irregularis (strain DAOM 197198w)|TrEMBL
MKITDKINNNLETSQPFYSFEYFPPKTDEGLNNLYDRLKRMSHLDPLFASFTWGAGGSTI
DRTTEMCATAQSLYGLESCMHLTCTNVVRGTIEKAMKEAKSAGIQNILALRGDPPRGQEY
WTSCDSDFTHAIDLVRFIRKEYGDYFCIGVAGYPEGNPDSENKEQDLKFLKEKVDAGADF
IITQLFYDVNTFVEWRDECRKNGINVPIIPGIMPIQGYNSFRRITNLCKIHIPAEILNVL
EPIKHDDQAVKDYGVTLAVSMISKLRNEHNTRGFHLCTMNLEKSVRLILEILGFVQTEEE
RNLRRLSRRRSSAGFGPNDIIRQEPDGSLPTAKPVIWKERSVDYLGRPEDWDNFPNGRWG
DARSPAFGELDGYGVSLRIPPEQALGYWQRPMTLDDLKQVFKSYILGEIPALPWYEEPLY
AETEAIRSKLVHLNELGFLTVSSQPAVNGARSDDPIYGWGPRGGYVYQKAFVEFFVSPEN
FEELVEKIKGNPWVTYCASNRNGDFRSNTKDDSPSAVTWGVFPGKEIVQPTIIAKVSFNT
WKDEAYALWTEWEHLYPKDSPSQRLLKDIGDNWWLVNLVYHNYVNSEEIWEIFFKS
>A0A2E1BCT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Martelella sp|TrEMBL
MTDGTGALTRPIEYSFEFFPPKSEDAAAGWWRAVEALSAYDPAFVSVTYGAGASSQAPTF
DAVKRLIDETDLVTASHLTVVKATSGEVDNVIRRFRDAGVKRFVALRGDAPDGVGAAYRP
HPGGYANAAALVAGLKAIDDFDISVSAYPEKHPESVDRAADIAMLKAKADNGADRALTQF
FFDNDVFEDYLNDVRRAGVTIPVLPGIMPVQNLNQLKRFAAMCGASIPDFLEKRLGNLVD
DPAAHFEVAADIAAEQVLDLQKRGISEFHFYTMNRSKLLIAVFDRLGIKPAESASDEKML
GRTG
>A0A845ZRH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO3E2|TrEMBL
MTNPTNNSFRTAVESGEFLITAEVAPPKGGNAAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILHQEGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQGTDLFTGAAVDPQLKSWSGLQRRFER
KLEAGAQFFQSQLICDFDRLEKFMNQIAAGSNKPILAGIFLLKSAKNAKFINKNVPGVDI
PEEIIDRLAAADNQLQEGIKIAAEQVKLARQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSPVNDLVFK
>A0A8E0FZB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 9.0111|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>J0URY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae (strain WSM1455)|TrEMBL
MMIAPQSESREEAPLADLLSHYSIEVTSRDLQSLESMTATLPQGCEVFIAHLPKEDIGLL
VRAAAGLRDAGFVPIPHIVARNIRNRLELDTMLARLSEEAGVRHALVLGGDRDDAAGAFG
SSLELIETGLFQAYGIDRIAIACYPEGHPRIAGAILDAALTAKIDAAARAGLDVLLVSQF
LFDPKPLLNFARRLRERGVTAPLSVGIAGPASRTKLLKYALRCGVGASLRALRERSEIAR
NVLSGETPEELLMEIAAAQATEPDLGISGVHFFTFGDPAQSIRWAEQQVDR
>A0A0P1LKP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kryptonium thompsoni|TrEMBL
MKKPFLERLLDDRPIICDGAMGTMLDLYEYHEQPRCIHNLLNPDIVARIHREYIEAGAEI
IETNTFDANRFRLEFYHLQDKIKEINKAGVEIAKSVAGDDVYVAGSIGPTGKLLEPLGKI
KTQQIKDVIKEQAEILISAGVDLIILETFVSLNELDAAIEAVKEVSDKIPLIAQKTFPED
GAILATDFPIEVVKHIKEKGVTVVGSNCTVGPQRMFSIIKSMYQDDVILSAQPAAGIPTL
VDGRSVYHASPEYLATYAKQLVEAGVKIIGACCGSTPSHIKAIANAVKDLRLKRPEVNIR
IKEQKHEKIEPPKESKVEIITAEDKKSNFAKNIGKKFLTTVELDIPRGLDMSSVIEGAKY
LKENGIDAVNITDGARARFRMDPVAISHLVETKVGIETITHIACRDRNLIGLQGLLLGAW
ALGIKNILAITGDPTKIGDFPHATTVADVDSIGLIKILKNMNHGLDAVGNTIGEPTNFLI
ACAANPTAQNLDYEISRLEKKVEAGAQIVFTQPLYEMRTLELFIKKIEHLKIPIMLGILP
LRSYKHAEFLHNEVPGINIPDWVREKLYLAHDDAGKVGVEISAQFLKEAKHLVQGAYLLP
PFKKYHIAVEILQKI
>A0A849HF81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidocella sp|TrEMBL
MIHSPHPATLQRWAAGARIAPLPAREGAAPPAISFEFFPPKTPALEAQLWACIERLATLR
PQFVSVTYGAGGSTQERTHATVLRIVKETSLTPAAHLTCVGATREEVDEVARRYWAAGVK
HIVALRGDAPNGEAYTPHPGGYAFASDLVAGLRRIADFEITVAAYPEVHPQALSPQADLD
NLKRKLDAGATRAITQVFFNNDIYLNFLDKALAAGITAPIVPGIMPVSNFKQAASFCAAC
GTSVPKWMAALFEGLDDDIETRRMVAAATTAEQVRILQANGIDEFHFYTLNRPDLVYAIA
RILGVKPLTA
>A0A126NVE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. PAMC 26642|TrEMBL
MMNAFRPSRHGTRRPKVSFEFFPPKTPEMETSLWESVRRLEPLGPSFVSVTYGAGGSTRE
RTHSTVKRMVEETALKPAAHLTCVSASRDEVDEVIRAYWDAGVRHVVALRGDPAGGLGTT
YEPHPQGYHQTSDLVAGLKRIGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAI
TQFFFDNDVYFRYLDKVRAAGIDIPILPGIVPVQNFRQTANFARKTGASVPQWLADRFEG
LEEDAATRRLVAAAVCAEQALDLIDRGAGDLHFYTMNKADLVYAICHLVGVKPEAAAARA
VAAE
>Q2S0T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinibacter ruber (strain DSM 13855 / M31)|TrEMBL
MKVTEHFDRESEPLISYEIIPPKRGGSADQILGVVEELMPYEPPFIDVTSHSAEVEYKQK
DDGTWTRCVKRKRPGTIGLCAAIEARFDIDTVPHILCKGFTREETEDALIELNYLGVENV
LAIRGDDNGYEKSISGNRSRNEYAVDLVRQIQDMNEGTYLEDLMDAEPTDFCVGVGGYPE
THFEAPNLAWDIMRLKEQVDAGADYIVTQMFFDNEYFFNFVDKCREVGIEVPIVPGLKIL
KRKRHLRLLPKYFHTEIPEELAAEVDAADPDDVERIGVNWAIRQARELMEAGVPGIHFYI
MSSADTVKKVVEPMHEEVA
>A0A0S3TV66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fischerella sp. NIES-3754|TrEMBL
MLDTQNPTSLTSFRTAAKAGQFLITAEVAPPKGGNPEHMLKMAATLKGRVHAVNITDGSR
AVLRMSPVVASAILLQHGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHADCKGVFDLESVRLLQVIQKLNHGVDYNDKPLNDGALDLFPGAAVDPQCPSWSGLQK
RFERKLEAGAQFFQSQLITDFEILEKFMDKIAADCGKPILAGIFLLKSAKNALFINRCVP
GVNIPQHIIDRLAQAKDPLEEGMKIAAEQVQIAQQLCQGVHMMAVKREDLIPQILEMAGV
TPVNQMVSL
>A0A0L6CR68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius tolerans|TrEMBL
MKTPRISFEFFPPKTLEASFRLWDTVHTLSPLDPRFVSVTYGAGGTTRELTREAVGTLHK
ATGLNVAAHLTCVDASREETLEIADQFAAAGVTELVALRGDPPKGSTGFTAHPQGFADSC
ELISALAETGKFTIRVGAYPEKHPEAADSRADIDWLKRKIDAGATEAITQFFFEADTFFR
FRDACVAAGIDAPIIPGILPIENWTGARKFATSCGTQIPAWLDDCFDKAIRDDRHDLLAT
ALATELCSDLIEGGVEDLHFYTLNRPELTRDVCHALGVTPRVTLRDVA
>A0A2S8YRG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MYb115|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLSQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKSNAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A257EB94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium PBBC1|TrEMBL
MSGLKLPISLEFFPPKTPEGAEKLRGVREKLYALKPEFCSVTYGAGGSTQEGTFSTVSAI
LSEGVAAASHFSCIGATKASVREELATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLV
AFIRAETGDDFHIEVAAYPEIHPQAKSPEADLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGYGDDVESIKAFGL
DVVSDLCEQLMNGGVPAIHFYTMNQSASTTEIVRRCNL
>A0A077MGY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetrasphaera jenkinsii Ben 74|TrEMBL
MMSNNTGIRRLLENARFEVLPTATIAEKVLASVPRDTTLTVTASPAKPLDATLGMAERLR
AEGYRVVPHLAARMINGRNELAEIVDRLRQADIDAIFVPGGDATPGEGHYTSAVELLDDL
ATIPHSFRQIGVTGYPESHPTIHDDVTIQSMWDKRRHATHIVSNMTFDAAGTAKWVRRVR
ARGVSQAILIGLPGPVERAKLLTMGAKVGVGESLRFLTKQKGVFARIAAPGYSPEAFLQK
LVRTADEPAMKIEGLHLFTFNQVAETQAWREQLLASAR
>F1YHL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia neofelifaecis NRRL B-59395|TrEMBL
MMTQVTDPISTDSDVRARAGQSVVERLADPHSGPVPFSVEFFPPRDAGEEARLWRAVRIF
ERMNPAFVSMTYGAGGSTRDRTVRIAGELATETTLLTVAHLTAVNHSIDELRGLVGAYAD
KGIVNLLALRGDPPGDPLGEWVKHPEGVAYAEELVRLIGELGDFHTGVASFPEGHHRAPN
LAADTGNLVRKLRAGADYSVTQMFFDVEDFLRLRDRIVAADPEQGAKPLIPGLMPITSLA
SARRMTELSGSTIPAVVEERLSKAAGDGPEENRAQVRAVGIDLCTEMAERLISEGVPCLH
FCSLNFAKATSEVLERIGIDTRGALAGV
>A0A069RIX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptoclostridium litorale DSM 5388|TrEMBL
MYISEKVKKAKPTISFEIFPPKKDGSLDTIYSTLDELKGLHPDFISVTYGAGGSTRGTTV
EISSKVQNHYKLPALAHLTCLTSEKSEIDGVLDRLEENGVKNILALRGDAPQNSCLDFSN
EFRYEHSTDLIRHIKDRGGFCIGAACYPEKHSESKNVWDDIVHLREKVDCGADFLITQLF
FDNEIFYKFMEKSKSMGIDVPVIAGILPVVNKKQIDRIVSLTGCTFPKKFTRIIERYEHK
PEALKEAGIAYATEQIIDLLSWGVDGVHIYTMNKSQETINILKSISTIRNVLGEVEAS
>A0A1W2FMY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kibdelosporangium aridum|TrEMBL
MTSVLERINVGRATFSVEFMPPRDDADEQILWRSIRELEGLDPAFVSVTYGAGGSRRDRT
IRTTGRVARETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVHNVLALRGDPPGNPMGEWV
KHPQGLSYAEDLVRLVCELGDFCVGVAAFPYGHPRCSDIETDADRLVQKFRAGAQFAVGQ
LCYSAEDFLRLRDRVAARGSDAPILPGVMPLTTPKMLSKVVELSGAPVPPQIASRLEPLV
DDPKAFRSEGIDVVTEMCQQLLAEGVDVLHFYTFNRAKATKEVLGRLDLVPSRTA
>A0A1M4DVC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea gerenzanensis|TrEMBL
MPFELICEIEPPTKPDLKHVRHQIGTMSKIASAFLIPDNHIGRATVSSVAVAHEVEAMGG
RGIACLNSRDRNLLGLRRDLLTAAAYGVDQFLFVYGDKPTSGNRTSDLNVRSMIDEARAF
SPGFRVGAAAGLRPLPAWKRTADFLFSQVSFSVEEQLRWREEHPVDVPVYAGVMVLASER
HARTLAAAIPDIALPEKLIEAVAADRMAGVEAACEQVLALRDSGAFAGVHLVPVARYRDV
ESRLAAAL
>C6RJ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter showae RM3277|TrEMBL
MLKEKILNKEKGLVLYGLTPPKAEFEESKLRDISDRWTGRIEGINADGLVLYEVQDESER
NDSERTFEFSGTLSPEIYYRDYLSVATPSVFYRVASGYNEDAFRAALAAQSSNLNVLVGA
TSSSQKVRLNLARAYEIAGEFENLAVGGVCIAERHAKKGDEPQRMREKIAAGAKFFISQA
IFDAQMTRKFLEDCAAAKITEPIFLTFSTAGNPKTLEFIKWLGVSVPSSVEDRLNASEDY
LAQSCEIIKEIWRELKQFGDENGLNLSANIESVMAKRAEIEASLELAREFRSL
>A0A3S2BW61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.08.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A182NHV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles dirus|TrEMBL
MAAVDDDGALRTKLKRIYNNPPTGTDAPVVSYSIEVAAKDDFDIERLRSLAPQPIFCSLP
WISDDNLRYADDFLRSPTLRLAGELRRSRYTVVSHVSCYNITEHQIDKLFTTADIRNVFV
IRGDTVNPAQTFQNSAGLVAYLRKREQSENRQLTVGVGGYPYGHHQSPTEADELRYLREK
IDHGVDFLLTQTLYDAGSFFRYRDRCRSAGISVPVVPGIYVPHSYRHLQAMLAITRIELD
PAVRAAFEAHADDEPEQFEAFAVEYFVGVVRELLEPNVARSSDPVRWVHFFTFNKFGLLE
KVLQQLGDYFR
>A0A812AGT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MKTALSKGQFVVTAEFYPPKEANGSEIKERALVLKDVVEAVVVRDNPLAQVHTSPIATAT
LLLNVGLAPIVQISIRDKNRFAIQSDILGAVTLGVKAFFCLEDCHQRVGDNPGAKGVFDL
DCVQLISIMKKIEHSLVGTRINPFAHPLELHLVNLSKKINAGVDFIQTMPVFDLERFKEF
ISLIKGENLYLLAGVRPIKSWQALQSMSQMVIPENIVQRIKNTPENKQAEEGIKICVEII
KALKQIKGVNGIHIFAHDWEEAVPILVRQANLK
>A0A1Z2XQQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acutalibacter muris|TrEMBL
MKIKELFNRGNVNFSCEIFPPKKDADFTEVFDVVDRISRLGADYISVTYGAGGSTSKKTV
EVASYIQNKCQTTALAHLTCIDSTPEQIQTQLAEFKANGICNIMALRGDKPKDFTGHAYY
NYAIELIKDIHAYGDFCIGAACYPEGHIECAHKQEDIFHLKEKVDAGVDFLTTQMFFDNN
LFYKFLYQALAAGITVPIVPGIMPIINARQVKRSAELSGANMPARFLAIADKFASDPLSM
EQAGIAYATDQIIDLIANGVKHIHLYTMNRPNTAEKILGNLSHIIR
>A0A1G1NUL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium RIFCSPHIGHO2_01_FULL_48_9|TrEMBL
MTKITDIFEQKPHTFSFELFPPKTDEGYQKLLETIKALAGLKPDFISVTYGAGGGSRDKT
FDIVQHIQDKHKITGVAHLTCVLHNKNEIKNILADIKNRGIKNVLALRGDPPKENPDWQP
GKDNFRYSSELCAFIRKNFGEHFGIGVAGFPEGHLLCQDRDRDAQFLKIKIDNGADFVIT
QLFFDNKNYFDYVARLRKLGVKARVLPGIIPITDYQGLVRFCGLCGATVTAELKKIFEPI
QNDKEATLKAGIDFAVRQCQELLAGGAPGLHFYTLNKSTPVDTILNQVRR
>A0A1G5QJD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiohalomonas denitrificans|TrEMBL
MESQNQNPGHFSFEFFPPKTDQGKAKLADAVDELKVLKPRYVSVTFGAGGSTQQGTIETV
RDLMERGLDAAPHLSCIGATRKSIRELLQGYVDMGVKRIVALRGDMPSGMREPGDFQYAN
ELVEFIRQETGDRFHLEVAAYPEFHPQAKSAEDDLANFKRKCDAGANAAITQYFYNVDAY
LRFVEDCQKRGLELPIVPGIMPIVNFTQLARFSDACGAEIPRWLRWRLEGLGDDKEAIRA
YGQDVNTELCRRLLEAGAPGLHFYTMNQAGPTTAIWESLGLS
>A0A4U1AJ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila sp. IMCC35006|TrEMBL
MDAAQKTSTPAAKNSPHKYTLIAEIDPPKGVRLNSFLDTALQLRGRVDGARVTDSEHAIM
RMAPIAPCLALKEKGFEPEMIITGRDRNRISFQADLLSAAALGINKIVIKEGHDPAEGDQ
PVVRSSGDLDLVSMLQCVSALNNGHDLAGESLDGATAFDIGVAIDLSDDVNFNRERAEFF
KQLGQYGVQSVTLGPTYDLNIVEQFIPFAEQTGIRLFTSVMFLKSVTMVRYLNNLRGVPS
IPQEFLKKMMEAPVKKDAGMQAAADLIRELAPLGEGVVLNAMGWRDRLPEFLDSIGR
>A0A4V7I9C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bibersteinia trehalosi USDA-ARS-USMARC-188|TrEMBL
MSYARTTDLLNQNLAELNGKVNVSFEFFPPKTEKMESLFWDSIQRLATLKPKFISVTYGA
NSGERDRTASLVKKIQQDTGIISAPHLTGIDATPDELRQIAKDYWENGIRSIVALRGDLP
AGYNKAPFYASDLVKLLKEVADFDISVAAYPEVHPEAKSAQSDLIYLKQKVDAGANRAIT
QFFFDIESYLRFRDRCVTTGIDVEIVPGILPILNYRQLEKMAKITNVKIPAWLHHAYQGI
REEDKNTAQIVGANIAMEMVKVLAKEGVKDFHFYTLNRADLSYALCHSLGVRAD
>A0A2I1XDU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria sicca|TrEMBL
MSYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHSIVKRIKQETGLEAAPHLTGIDASPEELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DNDQATRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A2M7YQW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium CG_4_9_14_3_um_filter_65_15|TrEMBL
MRVIEHLERAERTLFSFEIIPPPRGKTVREIIEMVEQVAPLQPPFIDVTSHMAEASYEEQ
PDGTIRRRVRKKRPGSLSICGIIQNRFGLDTVAHLLCTGFTREETEDACIELNYLGIHNV
LAVRGDQSNYRKSMVVGRSRNTYAEDLVAQLVDLRQARYLDEIANSEPIDFCIGVGGYPE
THLESPNVKTDLMYLKRKVDAGADYIVTQMCFDNAAYLSFVENCRAAGITVPIIPGLKIL
DNVRQISSLPKHFHISLPDDLVDEVLAAPDHAREIGLRWGRRQVEDLMNKGVPCLHFYVM
NDAGDVAEMIRNLG
>Q7W1Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)|TrEMBL
MTQSTAPAFSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRT
LRNLGCDAAPHLSCIGATRDQLRDILAAYREQGVRRLVALRGDLPSGMGGDAGELRYASD
LVAFIRQETGDWFHIEVAAYPEMHPQAESPSADLAHFVNKVQAGADAAITQYFFNPDAYF
DFVERAQAKGVAIPIVPGIMPITNHTQLVRFSEMCGAEIPRWIRLRLAEYGDDKASIRAF
GLDVVSELCQTLLENGAPGVHFYTLNHAEATLGIWKALNA
>A0A7K5JFI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Toxostoma redivivum|TrEMBL
MVNETQHSCSGSSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQFIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A0P6XRL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herpetosiphon geysericola|TrEMBL
MANPFLEQLGQRALLCDGAMGTQLYNRGNDFDECFDALNLTQPDVVREVHQSYIEAGADI
IETNTYGANRFKLEPFGLADKVRQINHRGMKLAREAREIAGTNTLIAGAVGPLGVLLQPY
GPLTEQAAHEAFAEQIGTLLEQGADLLMFETFSDLREMVIAVKAAKQVGDLPIVAQMTFA
EDGRTVLGNTPEEVVRKLGELGVAVVGVNCSVGPQRVFRVVQSMRAVNATIPISAQPNAG
WPTERHNRVFYPSSPEYMADYARRMVEELNVQIVGGCCGTTPQHISSMHAALQDLNPAST
LNITIVDDEAPSVQLPSKSAETTQLGRMLADGAFVTSVEIDPPKGHNPRRCLEGARQMQA
AGVNFINVADSPMARVRMSALPMCNLIQQQVGMETILHFTTRDRSLMGLQSDLLGAHALG
VRNILALKGDPPSFGAYPGTSGVFDVDTIGLVKVIAGMNSGVDTAGNDIGTPTNFLIGVA
LNINAEDPDWEIDRLHQKVAAGAHYAMTQIAYDAAELDRFLDKLGPLPIPILLGLMPVQS
YRHASFLHNEVPGITLPNEVLERMKQAGSNGRAVGVQVSQEILTAAYDRIQGVYIMPSFG
RYEMAAEVLEVLKATNA
>A0A895YEJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronosporangium hydrolyticum|TrEMBL
MVATSPTGPTGRHPSIGDLIRDQAPTFSFEFFPPKTPEQETILWRSIRDLETLRPSFVSI
TYGAGGTTRDTTVEVTEKVATETTLLPMAHLTAVNHSVAELRNVIGRLAAAGIRNLMLIR
GDPPGDPEGDWVQHPEGLRYAEELVQLARQIGDFSVGVAAFPYKHPRSSDMAEDTAHFVQ
KCQAGADFAVTQMFFDETEYLRLRDRVEAAGCDTPIVAGVMPVTSMRTIEMSEKFSGAPF
PAKLGEEFAKVADDPKAVRALGIAKASEMCRRLLDEGVPGIHFITLNRSTATREVWENLG
VSATA
>A0A2G1QQ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zhengella mangrovi|TrEMBL
MASPRFTRTPGSGQPLSVSFEFFPPKNEKMAERLWETVQRLAPLAPDFVSVTYGAGGSTR
ERSLDAVRRIIAETDLDVAAHLTCVDATREEVDTVIDEFVASGVRRFVALRGDPADGVGA
QFKPFPGGYVNGADLVGGLHAKGDFEVYVSAYPEKHPESPDFATDIEMLKRKVENGATKA
ITQFFFDNDNYERYVERARRAGIYIPIVPGILPVHAFTQVASFAGRCGASIPQWLADRFE
GLEDDPQTHQLVAAAVAAEQVLDLMERGVDDFHFYTMNKPDLVFAVCHLIGIRANKPDEP
GAKAA
>A0A5D9CZU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. B1(2019)|TrEMBL
MVIKRITHKLPDISAAPIIPASIEASPAQVLGASDLAGLFPQGVRVYLTDTGAASQDRLV
EAAAHLRNLGYEPVPHLAARRIPSSAAFVEQVRRLAGEAGVTDVLVVGGGVERPVGPFAS
SMDMLSTGIFDRCGINQIAIAGHPEGSPDFNDDTAMAALRLKRDFAERSDAAMRIVTQFG
FDPARFIAWAEGLIASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LARGHSPESIVGPIERHWQASPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGAADRAAS
PDSRAG
>A0A2S7T744|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureicoccus marinus|TrEMBL
MKVTDHLKQNKGETLFSFEVIPPVKGKSIDELYKNIDPLMEFNPPFIDVTTSREEYVYIE
RGGLLDRKLTRMRPGSLGICASIKHKYDVDAIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDSMKEERYFEPTEGGHQYASDLVKQIKQLNQGNYLHEVIESDNCSDFCIGVAGYP
EKHMEAPSLQSDLKRLKEKVELGANYVVTQMFFDNQRYFEFVDAARDMGIEVPILPGIKP
IAVKKHLQLLPQVFRVDIPEDLIEAVETCSDNKAVRQVGIEWAIQQSKELQEKGVPVIHY
YSMGKSDNIKAIAQAIF
>A0A0L8FPL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Octopus bimaculoides|TrEMBL
MDEINNKQESNGLLRKSSMKNNFISLNDQMKLRMSSNDPWFSLEFFPPKTTNGARDLFDI
MECFAESQPLFCDMTWHLKNDPQNLEKPTSSLCMAGTMLNYFNLPTMLHITSYSQSVSEI
KDILLKAKDQGIRNILALRGDIFPGHVASTVHELPYAVDLVRLIRKEHGDHFVIVVAGYP
SGHPECASYEEDLKHLKEKVDAGADFIITQLFFEMHTFEKYVKDCREIGITCPILPGILP
IQSYLSLHHVSKLTKLTVPEEILNSITPIKDNDEAVRNFGVHHAVELGKKLLNSGLTKGI
HFYTLNQRFATTTILKQLGLLNEEINKPLPWKPSVNYVRLNEEVRPIFWKGRRKSYICRT
ADWNKFPNGRWGNSSHASFGNLTDYYMFYLNYSSNEEQLKSLGFQLETEQDVWNVFYYFI
KGHENQNGVKVTHIPWSDDVLSTETSLISDQLAYLNKNGVLTINSQPAINGFSSTHPIFG
WGNPDGYVYQKAYLEFFTSKENVEVLKKLLVNYPQVNYHIGNSQQLKWIKFSGLVIKFLY
LKDHTRKETFDEMEKVNGDDAPSYNVVKHWHASSNVVRHWWKLLLFLDDHILPFMTTPSI
KQKPPFWRITA
>A0A2V7NAK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
ANPVKLRSYGLADDTEQINQAAAELARNAAGGHASVVGAIGPLGVRIEPFGALAREEACA
HFARQVDGLLAGGVDGFILETFSDMDEIHAALRAVRSRSDLPVIAQMTIGDDGLTHYGTG
PETFAKQLTAWGADVIGVNCSVGPAGVLEAVEKMVKVTDRPISGVPNAGLPRDVGDRKIY
LASPEYMASYARRMIEAGARLVGGCCGTTPEHIKKIRDYVASVVPRHPPVVVSRAEIRAP
AGAEAVPLVQRSRWGAKIARGELVTSVEIVPPKGVDATPMLEQCRALKAAGVDAVNVPDG
PRAQSRMGVLPSAILIEREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRNILIITGDP
PKMGPYPEATAVFDIDSIGLTNLVFRLNHGLDPGNNPIGAPTRWAIGVGVNPGAVDLDRE
LSRFAWKVDAGAEFAVTQPVFDPAQLEAFLARVGQFKIPIVAGIWPLISLRNAEFLANEV
PGVSVPESVLARMRQAQDKGKEAALAEGVKIAREMFQQVKRSVQGVQVSAPFGRVEVALE
VFG
>A0A1Y6L041|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium aquimaris|TrEMBL
MVNLDQTTQTESELRVRYNDITRGVYFIGTTPPKTSTPLEEVEGIADRLVNRIKDLAIDG
LIVYDIQDEVSRTQKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSETDAFDEWL
NEAWHEYQVRDIVLVGSPSAKNEVSLPLSAAYQTLAENNNNFFTGGIMIAERHAKKGNEH
ARLIEKYQQGCNFFISQAIYDTQATIDILTRYAIECKQDGIKPQRILLTFSPCGSAKTLE
FIEWLGVSVPEATSLRILNASNPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRK
EEIDGSILLYKLLRASMDSHLAKHEFRTLQRNKLTSV
>A0A5C1QC17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiospirochaeta perfilievii|TrEMBL
MLKINYLEKVKKGITLFDGAMGTMLYDKGVFINRSFEEVNITNPKMVSKIYKEYVEAGAQ
VLTTNTYTANRINLGGYNLADRVEDIIKSGVLLAKEAAGDELYVAGSIGRAPNGTSYKEE
IEALTEQVKLLIDCGVDIILFESFSDIDLLLELCEITKKYKNIPVQAQFTLPPVAPSEYI
KLGRLYAQRLDRSKFTDVIGINCTMGPAEMLEILQDTINFIHKPFSIIPNAGHPKVVDGR
QLYLSTPEYFAEYAKRFLDGGASVTGGCCGTTPQHIKKMADAVLSLDRGYQHIELAQVED
GVEFKTPLPLEKRSSLGRALKEGKWIETVELVSPMGSDISGFMSRVKLLDQAGVKYINIP
DGPRASSRMSAFGTALHIKQSSNIEPILHVCGRDKNLIAMQADFLGAESFGLRDMLLVTG
DPPKVGKYPDVTGVFDVDSIGMLDMTKRLNSNVDIGGASLTSGTAFVSGAGINPVAPFID
REIERAFQKAEAGAEFFISQPVYDIDLLSKFIDRIKGTGVPVIIGVWPLASYRNALFLQN
EVPGVEIPKEIMTRMEKHSDKESARRDGVLIAREIVASLKEKIQGVQVSPPFGNINTALE
VLSKDIKY
>A0A2V7MNL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYSKGFFLNVCYDELNLKQPRLVQEVHAEYVRAGAEILETNTFGANPLKLNSYGLA
DETEKINRTAAELARAAAGGRASVLGAIGPLGIRLEPFGPTSKAEAETAFARQVQGLLAG
GVDGFILETFSDMDEIHAALQAVRAASDLPVVCQMTVGTDGLTYYGTDPETFTKQLTAWG
ADVIGVNCSVGPAGVLEAVEKIVKATDRPISAQPNAGLPKDVGDRKIYLASPEYMASYAR
RMIEAGARFVGGCCGSTPEHIKKIRDYVASVVPRQPSVVVSRAQVQAPAGVVPVPIAERS
RWGAKLARGELVTSVEIVPPKGVDPASMLAQSRALKAAGVDAVNVPDGPRAQSRMGVLPS
AILIEREVGIETVIHYCCRDRNLLGMLSDIIGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLTNLVYRLNQGLDPGNNPLGGATQWVIGVGVNPGAGDQDRELSRFAWKVDAGA
EFAVTQPVFDAGQLETFLKKVEQFKTPIVAGIWPLISLRNAEFLANEVPGVSVPDEVLAR
MRKAQDKGKEAA
>A0A6L8G3N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MDNPTVPMQPFLAALHHRPLLADGALGSYLFALTGRVSEQNHLYEAFNLTRPALVRQLHL
EYLQAGAQCLTSNSFAANATYPSAVSIAELNAAAVRLAREAIDQYCQQAQYSDPLFVLGS
LGPPLPAAQAPRTASDLYRAQIEALVEGGVDALLLETFTCLDQVAALLELLQDLDNPVPV
IVQMALHQRDGTWEQAPQAYIQTAASLGADVVGINCCALAEARAFLDAAQECASVRDGQV
QLAVMPNGGEFRRVGHRYLTGVNPECMGRFAREMAHKGVRLIGGCCEVHPSHIHEMHNYL
HGLAAGERIVPLARTPDQQPIDATAKRRNGPFSRKLIDGQFAVSVEMLPPRGTGGLKARL
AFIAELAASGLADALDITDGSRGIPLMPPGDFIHLIRRRLHWERDRLELIPHCTSRDLNV
MGLQSRLIGYWANRIHNVLFITGDPPKMAPTYPRSTAVFDLDSAALIRYTHAFRNAGVEF
VGQPLGSHRDPRTHFTIGTGCEPEALDLQREWERLAHKIDAGADYVMTQPTFDRKALAPL
TTYRAQVPIIVGVMVLRGLEHARRIAEVPGVIVPEAIFAKLSAYADPADQTKAGVELAAE
QVRQVRAEGWSGLYLMSPAGHQPVLEVLKRGLG
>A0A6L7W2K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MRFLDYFTGNQPVISFEIYPPQTQGGMRALKARVIPNLLKLNPSYMTVTYGAGGSTRAKT
LEIASLIQNEFGLTAACHLTCVGSSRTDIDDILKAIRTEGIRNIVALRGDPPRGEDTFVP
AKDGFAYGNELVAHIRSTEPKDDGFGLAVAGYPEKHLEAPDFDTDIENLKRKVESGGDII
ITQLFYNNDYFFRFVDRVRAANITAPVVPGLMPILAAGQIQRIASLCGSEIPEDLQDQLK
GAVDDEDKAMRIGIDQCIGQATELLEQGVPGIHFYVLNKSIHMRRIISALPL
>A0A8D0YSM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRSVGFQPTPDASLTPRAHGKGVKGGAPPGAPVQKETPHRFDRM
GAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEVTGYLH
KAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKGHPD
AESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACSEMGITCPILPGIFPIQGYH
SLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTL
NREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDE
FPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQELTSEESVFEVFAHYLSGEP
NQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGWGPS
GGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGI
FPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMLIQYIHDNYFLVNLVD
NEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>A0A7X3TPQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MPQYFKLAKKIHVGAAFVISQIGYDARKQDELLKYMALCGLDVPVIANVYVLSRPAARFF
HKGHIPGVEVTDELMAVVEKQAQANDKGRAFFLELAAKQCAIAKGLGYRGAYLGGHLQYG
DYEKILALAATYSEDDWRDFAVELCFSFADEFYFFEPQGDTGLSSTTINRAYLASKEQAA
LRQARGHLPLSYKLNRRIHDQVFAPESAGFRTGAHLARALTEHPKAAKLFHAAEHALKIA
AFDCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTRQGKCEVGDKDCIWARAYDRLKAY
GEEEQMLGDAAVIKDAALQGTSAWTNAFLQKDHRSKKKDSQ
>A0A6G6W1X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. 4R-513|TrEMBL
MSIGIVLLTPRCRDARKRKGPRSVARTTPAPNRQAARELVRDFSLEMTGKDVPGLEEAKH
AIPLGTKINVTFLGNEDLEMRVAAAKAVKDLGFVPVPHISARRLSSQDQLEEFLGRLQEV
GATEHVFSVGGDPTTPEGPYEDSLSVIRSGLLSKYGVREVSIAGYPEGHPDIKSDVLWRH
LEDKSAALKEQGLDAVILTQFAFDTDPVVEWIKSVRERGIGSEIRIGTPGPAGIKRLLGF
ARRFGVGANAMIVKKYGFSLTNLLGTAGPDQFVTDLSSLLAQEPSAGSVKLHFYTFGGLL
ATSEWAREFSAAQS
>A0A2V7JCN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
ALKAAGVDAVNVPDGPRAQSRMGVLPSALLIEREVGIETVIHYCCRDRNLLGMLSDIIGA
HAAGLRNILIITGDPPKMGPYPEATAVFDIDSIGLTNLVYRLNQGLDPGNNPLGGATQWA
IGVGVNPGAVDQDRELSRFAWKVDAGAEFAVTQPVFDVHQLEAFLQRVEQFKIPIVAGIW
PLISLRNAEFLANEVPGVSVPEEVLQRMKKAQEKGKDAALAEGVAIAREMFTKVKQLVQG
VQVSAPFGRVEVALQVFAP
>A0A505DGB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sporangiiformans|TrEMBL
MGGAGLRALLRSVRYEVLPAKATEDKVVAHVPRDVVVTVTASPVKGLEPTLDLVTRLAAH
GYRVVPHVPARLLRDDGHVKEVVDRVREAGVDDIFVPAGDANPPAGGYDGALPVLRRLSE
LGRPFTHVGVTGYPESHPLIHDDVTIQSMWDKREHATYIVSNLCFDPRVLGQWIARIRRR
DIPLPIHVGVAGPVQRAKLLSMAAKIGVGESTRFLTKHASWFLRFAAPGGYSPERLLART
EEELTAPSAGVAGLHLFTFNQIAETERWRCAVLERLEG
>A0A3R9XFQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC07149|TrEMBL
MALGTASTWSDRAHTVRDLLASGASYSFEFWAPKTERGERNLWNALRRIEAVSPSFVSVT
YGAGGSTRGGTVRATQQIASDTTLTPVAHLTAVDHSVAELRHVIGQFADAGIRNMLALRG
DPPGDPMGPWVRHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVAKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
DAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A1Y3X818|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor sp. An52|TrEMBL
MKIIDILNQDRPTLSFEVFPPKTSDTYDSVARATQDIAALRPDFMSVTYGAGGGTSDYTV
GIAAGIQQQYGVDVLAHLTCASSTRAHVAQVLEHLKEKGIQNVLALRGDIPEGGAPAHDY
QYAAQLVKDIKAHGDFCIGGACYPEGHPESPTKNADIDHLKAKVEAGCQFLTTQMFFDNN
ILYNFLYRIREKGITVPVVAGIMPVTNGKQIARICKLSGTYLPERFKAIVDRFGDNPAAM
RQAGVAYAAEQIIDLIANGVEHIHIYSMNKPEIAASIQSSLSEVLK
>A0A425W6R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacteriaceae bacterium|TrEMBL
MKLSEQFKVDRPMLSFEVFPPKTEARFEPIMSAVEEIAKLDPAYMSVTYGAGGGRSQYTV
DIAKSIKAMNVTPLAHLTCVSSDKTTIQTQLTALKAAGIENILALRGDLPKDYVPGEYRH
ASELIDEIHRFDGEFCIGGACYPEGHPESARQKDDIQHLKEKVDCGCEFLTTQMFFDNDL
FYNFMYKIREAGINVPIIAGIMPVTNAAQISRIVDLSGAFMPQSFLNIVDHFRDDPASIY
EAGIAYATEQIVDLFANGINHVHVYSMNKPDVAADIQNNLKSILDK
>A0A2V7RJX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
HYCCRDRNLLGMLSDIIGAHAAGLRNILIITGDPPKMGPYPEATAVFDIDSIGLANLVYR
LNQGLDPGNNPIGGATKWVIGVGVNPGAIDLDRELSRFAWKVDAGAEFAVTQPVFDQRQL
EAFLKRVEQFRIPIVAGIWPLVSLRNAEFLANEVPGVNVPDEVLQRMRKATDKGKEAALA
EGVAIAREMFARVKTTVQGVQVSAPFGKVDVALEVFRT
>S0FJG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminiclostridium cellobioparum subsp. termitidis CT1112|TrEMBL
MIKDIYTQKRTVFSLEVFPPKNDTDILSVYSALDGLKALNPDFISITYGAGGSTSKRTMD
IAAYVQKQCHINALAHLTCVSLDEILLGKFMEELKANQITNVLALRGDRPRDMTDGDFHS
RPYKYASELVSIIRQNYGFCVGGACYPEVHPESRDQESDLYFLKAKIEAGTDFLLTQLFF
DNSKFFSFYEKLRHAGISVPVSAGVMPITSINQIKTIVDLSGAYIPSRLKELFEKYRNDP
EDFKKAGLEYAIEQIHELLHHGVQGIHLYTLNKVDTSTEIFKNL
>A0A2V7N4I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
VEQFKTPIVAGIWPLISLRNAEFLANEVPGVSVPDEVLARMRKAQDKGKEAALAEGVAIA
REMFTRVKQMVQGVQVSAPFGRVEVALQVFQ
>A0A1F1DHM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC072C09|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFAHQPNFEVN
>A0A379XXU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. indica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2E7MLA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
IPHFTTRDLNAMGMQSRLVGYWANRIHNVLFITGDPPKMSPTYPRSTAVYDFDSTTMIHY
THSCLNAGVDFGGRPLGQHAEPRTRFTIGSGFEPEALNIENEVEKLRHKIGAGADYVMTQ
PAFRFDPLGVLDSFRPQVPILIGVMIATSLEHARRIGQVPGVVVPQSMYERLGKYENSAD
QARIGRDIAVEQVRWIKKRGWAGLYLMSPASHQPIIEILEAGLS
>A0A2M6VKJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. B9-3|TrEMBL
MHDAPMRETAMTVNNSLSIEFFPPKTPEGADKLRAVRQALYTLKPQFCSVTFGAGGSTQA
GTISTLSEILSEGMMAASHFSCVGATRDSVRHQLAEFKAMGVKRLVALRGDLPSGYGAGG
EFQYASDLVAFIRAETGDDFGIEVAAYPEIHPQAKSAEADLQAFATKVKAGADSAITQYF
YNSDAYFRFVEDADKLGVHIPIVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGYGDD
MASIKAFGLEVVTDLCDQLRCAGAPGLHFYSMNQSASTLAICENLGLLTSAI
>A0A4R9IYT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira yanagawae|TrEMBL
MNQILLEIVPRDINSVLQDVNFVKSNFHQITGINIPDLLRFDNRSWEVASSVLPIFSNVI
PHIRAIDFDINNCENLIHTLKSHQIPSVVVIKGDPPTDMSKRVYPTTSIQMIKNLKKEIP
QLKVFAAIDQYRVGIKNEFDYIELKKDAGADGFLTQPFFDMRLVDIFSEKLNGLEVYIGI
SPVITEKSQSYWESMNRAYFTKDFQPSMEWNVKFAKDVISYCSKIGMNAYLMPIRINLAE
YLHHIFT
>A0A517SZL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium SV_7m_r|TrEMBL
MTLATLFTNSERCEISFELFPPKTDKGMQNLQDNVQKLLRFNPAFLTCTYGAGGSTQSRT
LEVVELVKQISGLPVASHLTCVGSTVEQLNDYLTEAKRRGADYIVALRGDPPQGSDEFQA
VDGGLSYANELVELIRRDHADQFGIAVAGYPEVHQEAPNAQTDLDNLKRKVDAGADIIIT
QLFYDNADFYRFRESCEAAGIRVPIIPGLLPVTNYKQAKRIAGMCKAAIPTEMSTAMSAN
DDPDFQFECGVQHARNQTIDLIHNGAPGIHYYVLNKSDAAEQLLSDIDFEKKA
>A0A7X3PXG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0667_bin_9|TrEMBL
MTPRTLQHTLVQGQFAVTVELNPPKGTDVSELLETAKSLSGRVHGINVPDNAAAVLRASP
VAVARLLYEQGHDPVLQVTCRDRNRLALQSDLLGAHVLGIRNVLCLTGDSPGTGDHKDAK
PVFDLDTVQLMHAVQELNEGRDLAGNALEGRTAFFIGGAAAPGAEPAELLHKKFEAKVNA
GAEFFQTQPVFSAKVIHPFMEAVRPYSRKVLAGVLVLRSVKMAEYVNARVPGIDVPDEIL
QELRNAGDARVSEAGLEIAVRTIRAVRPFCDGVHLMAGRLAHRLPEIIRKAELS
>A0A532TE71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon Loki_b32|TrEMBL
MNLYQVRKNQKRRKRYKMPQRPAYSNLVKAIREGKFVFTGELEPEKDFDLKHVLHSAEEM
KKTGKIIAANVTDGPQGDAYTCSMVPCYLVQEKVGLEAIWQMTVRDRNRIALFGDILGGS
ILGLKNLLALTGDHSALGDHGNARAVYDLDSTQLIELVSKMVDEGTDLEGNEIQGGKPQI
NVGCAANPNSNPRDPEILKVGRKVDVGADFIQTQTSFDVDDAKEFLKELEKYNIPVLLGL
FPIKNYGIAWYFNEYIPGVSVPKDFLDALKATKKIKDKQQKYAAIDKINLEFYEPFIKEI
KKTTKAAGIHCMAVHYERLFEPLLKDF
>A0A7Y5LUF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MSEFLETLAKRVLVCDGAMGTVLYEKGISFDHCFDEINLSHPEMVRAIHEAYIDAGADII
ETNTFGGNRFRLMHHGLEEKIQAVNAAGVRIAVTTAKYKTEALGRRIFVAGSIGPLGKPL
EPIGKITHAEARAYFAEQAKILADNGADLLMIETIGDLEEAREAVTGARSVTGLPIVAQM
TFNDEAKTLMGNKPSEVARVLKEAGANVVGANCSVGPQALLEVLEKINIVPDIGFSVQPN
AGLPRLVGGRYIYLASPDYFSDYAKLYMQAGANIIGGCCGTTPEHIRQIKKAIGDQPPKK
IEKKTVVIETEESSKAEQPTSHLRSSLIDKFRDKKFVISVELDPPRGLNYDKVIEGAVMC
RRHNVDAINIADNPLAKAGMTPLAMAGLIKQSVQIETILHFSCRDRNLIAMQSELMSAHV
MHIRTILGITGDPPLVGDYPNATGVFDVDSIGLINLIRNLNNGIDLAGKSIGSRTNFFKS
CAVNPTAVDMAREYDRYDQKIASGADFAMTQVLYDLKPLEDFAEKYKGKIPVLLGIMPLK
NAKHANFMHHEIPDITIPENIRERMTKAGDRGQEEGVLIAKEFLREAKSMVDGVYIMPPF
NKFEMAFDVLEVL
>A0A7C1L087|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKLIELFKQSKFVITSEVGPPKGIEVEKVLNEAEPLRGIVDAFNVTDLQSSVMRLGALPT
CHLLKERGLEPIFQITCRDRNRLALQSDILSAAVLGVENLLLLTGDHPKLGDHPGAKPVF
DLDSVQLLSAVKGLMENKDMEGNQLEGKAPEFCMGAVVNPGADPLEPQIIKME
>A0A840BQW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niveibacterium umoris|TrEMBL
MTDKPTFSIEFFPPATPEGVEKLRLARAQLAQLNPAFFSVTYGAGGSTRDRTLEIVREIQ
AEGLHAAPHLSCIGATKDSIRDHLAEFREMGVTRIVALRGDLPSGMADPGEFRYANELVA
FIRAETGDAFHIEVAGYPEFHPQARSATADLDAFATKVRAGANSAITQYFYNADAYFQFV
DEAWARGVEIPIVPGIMPIASFSKLARFSDACGAEIPQWMRRRFEALGDDTASVKALGLD
IVTELCERLLEGGAPGLHFYTLNQAGLTTTIWQRLGLA
>A0A7X7QZ73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKPLLQRLAEGPLLGDGAMGTMIYARGVFINRCYDELNLSTPDIVSGIHAEYVAAGAELL
ETNTFGANQIALAAYGIADKMAAINSRGVEIARAAAGDEVYVAGCMGPTGRSLGPEGNVS
NEEAACAFASQAQALAAAGADLIMLDTFHALDELIAAITAVKAAVTLPVVAHFSFDTKTS
RQTDVKRRSPGAVARLLDEAGADVVGTNCVTGPAGMLTIVEGMARATHKPVSAFPNAGFP
EEHGGRILALGTSPEYMAEYARRLVQSGASIVGGCCGTTPAMIAEMGRFLKGIAAERRSR
VFVREVAATKLLEPIALAERSRLGALIAGAKGDRKIISVELTPPAGLDPVKAIRGAKMLK
DGGVDIVNIPDGPRAVARMSPIALAGLVRDQAGMETLIHYCCRDRNLLGMQMDLLGANAL
GLHNVMLITGDPPKVGNVKAATPVFDLDAIGLINMVNRLNRGFGLADQEIHGRTQFVIGA
GCNPGAIDLEREIRRFGEKITSGAEFFFSQPVYRPDLLDGFLKATDAFPRVPFFVGILPL
ASLRNAEFLHNEVPGMQIPEEILKRMRAAESKEEQQREGIRIAQEMLREVVKNPRVKGIY
LFPPFGRYESVLEVLEAL
>A0A8D9XU17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella ceti M490/95/1|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNHFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>B7HPF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus (strain AH187)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKETAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7V3UM68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MSSLFLERLENDILLCDGAMGTMLYEKGIYINRCFDELNLSMPELVQEIHREYAACGVDI
LETNTFGANRFKLQTHSHGDKVRDINLQGARIARKVAGKDLFVAGAIGPLGKRVEPLGKI
AEAEAREAFKEQAEALLEGGVDLFILETFSDLNEIRYALEVVRELCDLPVVAQMTFGDDG
NTLLGEKPSKVVQTLGAWGADVVGANCSIGPQVMLETITEMAKTSSVKLSAQPNAGVPQL
IEGRFIYLCSPEYMSTYAKRFIRIGLKILGGCCGTTPAHIKAMGTAVKALKPRQVSVSVK
IPEPPKKAVIPVEVAQKSQLARKLSEGKFVISVEVSPPKGVDTSKILQWAQLFKENGIDA
VNVPDGARASARMSPLALTYLIESRVGIETIIHYCCRDRNLLGMQSDLLGAYALGLRNIL
AITGDPPKLGDYPSATAVFDVDAIGLVRIINHLNRGEDLVGNAIGAPTSFHVGVGANPGA
MNLDEEIRRFELKVESGAEYVLTQPVYDVRLLENFLRRTARVKIPMLVGILPLRSYKNAE
FLHNEVPGMQIPDAIRERMRLAPSETAAEEGIRIAQEALKEAKDMVQGVYIMPPLGKYEA
ALRVIEILK
>A0A522QUE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MLEDLRSGILLADGAMGTMLIAGGAAPHTCLEARNLEQPQAVRTIHERYVEAGADLIETN
TFGANALKLADFSLEHRLTEINAAGVRLARHAARSASRRVYVGASVGPLGKALQPYGTMT
EERAVEIYREQCAALAAERPDAFVLETLTGLAEARAALRAALDAAPDIPRICTLAMLEGG
QTQYGEDAGEVLRALIDAGADAVGLNCALGPAQTYEILAPIAGDFSVPLAASPNAGFPGR
LHGRTVYFSSPEYFAEYAGAFAELGVNLIGGCCGTTPAHTAAMRAALRGASLGDRRAVHV
VSVHDYERPAAPPPLRRGHAFEERLGREFVITAEIEPPRGIDYRAQLAGARMLEEAGADA
IDLTDNQRAQLHMSPIALASLLMQHTKLATILHFSCRDRNLLALQAELLGAAALGITAIL
ALTGDPAAFGDYPVATGVYDVTSVGLVGILRALNDGKRHGGIDIGPPASFKIGVAVNPLA
RDIDSELARFRQKIAGGAHFALTQPIYEIEALRRFVSELDRAEITRIPILAGVLPLRSLR
SAEFLHNEVPGMFVPEGIRDRMRRAGENGSREGVRIAREFVEEARTLVGGAYVIPMGRYE
AAAEVIAPIAAAR
>A0A4V1V8J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MNTKQKPALSLEFFPPRDTAAQERLVQAATHMLAIQPKYVSVTFGAGGSTREGTAGTVRT
LTNMGCDAAPHLSCVGSSREQLREILAAYKAAGIRRVVALRGDLPSGMGGGSGELRHATD
LVRFIREETGDWFHIEVAAYPEMHPQAASPSQDLAHFVEKVQAGADAAITQYFFNVDAYF
DFVDRAQAKGVTIPVVPGIMPITNHSQLLRFSEMCGAEVPRWIRLRLAEFGDDRASIRAF
GTDVVGQMCQDLLDE
>A0A1C5C177|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MnatMP-M27|TrEMBL
MTLATDQEGPAPRTARAAVAHALRNATYEILPFKSAEEKVLAHVPTDVALTVTTTEAKGL
GPTIDLAASLSKQGYSAAPHIAARLVRDRAHLSDIVDQLRDSGIDRLFCIGGDAAEPVGD
YVDALSLLQGLRDLGHPFSSIGIGGYPEGHGSISDELIERALESKAPYADLIITQLCFDA
DTTIRWARKAQDRGITLPIRVGIPGAISRQKLIRVSAGLGLGQSARFLKKQQTMFWRFFL
PGGYSPNKLIQKLTSAFAEQDNNLRGFHVFTFNDLDSTEAWRKAWLARLT
>G4TUD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serendipita indica (strain DSM 11827)|TrEMBL
MRITEKIEKAEKQNRVWWSFEYFPPRTAQGFQNLVDRIERMRHLGPEFIDITWNAGGRTS
ELTSEMVKTCQSLLGIETCMHLTCTNMPSEKVDIALREAKSHGCRNILALRGDPPAGQDE
WTAVDGGFVHGIDLVRHIRKNYGDYFEIAVAGFPEHAMLSEEEQQVELQYLKEKIDAGAS
FIFTQMFYDLDLFVRWVHSVRKAGITVPIVPGINPIQTWNGFMKATSLAKITIPQSYLDV
LEPHKNNDEKVRELGTKLVADLCRGILNAGLGIRGLHFYTMNLEKGTRMLLEELSFVPRV
ETVKPLPWRQCLTPSRRSETIRPIFWANRTKSYLSRTENWDQYPNGRYGDARSPAYGELD
GYGISLKHSKEDAQKLWGHPQTKEDIGKLFATFCRGKLAALPWSDEAPAAETTVISEHLA
KLNELGFLTINSQPAVNGLPSTDKIHGWGPENGFVYQKAYLEFFVSPTLLAALIPQIERD
PLITYYAINKRGDLRTNTQSEGPNAVTWGVFPGKEVIQPTIVEAVSFMAWKDEAFELGMQ
WSQVYDSGSPSQALIANIMETYTLVNVVHNDFRDPEAIFTPFYRAAQSLNSSGLTNGHV
>B0RM81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. campestris (strain B100)|TrEMBL
MSPDPPSRAATITDAYSLEVGAHDMPALTAAAPQIMRGSSMFIPYLPSQNDDARLAAAQR
VRALGFAPMPHLSARRIASRYALQAFVRRAVDEAGVERCLVIAGDAPSAVGPFSDSVSLI
ETGVFERSGIKAIGVAGHPEGHPSMPASAQWDVLERKCRSIAERGMAPLIVTQFAFDADT
VLTWLEALRARGIAHPVHVGVPGPAGVAVLARYAARCGVGACASMLSKYGISLGKLFGTA
GPDRFVDRLTAGLSEAHGDVSLHFYPFGGIAQSVAWVEQYRSRHARPLAD
>A0A496UL97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MHVTDHLDRAQRTLFSFEIIPPARGKSVGDIIRMVEQIAPVKPPFIDVTSHTAEATYDEL
PDGTIKRRVRKKRPGTLSICGIIQNRWGIDTVPHLLCTGFTKEETEDAVIELNYLGIHNV
LAIRGDEPNYVKAYDKSRSRNIYARDLVSQLADLRRGRYLEDLTGSEPVNFCVGVGGYPE
KHVEAPNFKTDIRHLKAKIEAGADYVVTQMFFDNADYFRYVKLCREAGIEVPIIPGIKLI
DGARQLTTLPKHFHVSIPDQLVDEINESPDHVGEIGKRWSRKQVEGLIEGGAPCIHFYVM
NDAAPAVEIVRDLV
>A0A1M4YGD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoreibacter ascidiaceicola|TrEMBL
MTRPNVSFEFFPPKSVEASFRLWDTIQMLAPLDPTFVSVTYGAGGTTRELTHEAVTALHK
ATDLRVAAHLTCVDATREETLAIARDYIKSGVTDIVALRGDAPKGQDFTATKDGFASSIE
LIEALKTETEATIRVGAYPDSHPEAGSMEANIAYLKRKFDAGADAAITQFFFEADTFFRF
RDACVKAGIDKPILPGIFPIEDWTRASNFAKRCGTVVPAWLEEAFTTAIRDDRHDLLAQS
VVTELCSDLVDGGVDHLHFYTLNRPELTRDICAALGVTQKVALAQVA
>A0A1P8UZ21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger abyssi|TrEMBL
MALLNFRKPKPAVPGASLESFLAGYSIEVMPRTAAKVEDFRALLPRGTRVYIAHIDGTPI
EEMVDTARRLAGEGFEVMPHFPARIISDKAMLADWIARYQGEAGVHQGLILAGGVDTPKG
DFHSSMQLLETGLFDKAGFDRLHVAGHPEGNRDIDPDGGDDTVMQAARWKQDFSERTDAR
MALVTQFAFEAEPILAWGQRLRDAGVTLPIHIGLAGPAKLQTLIKFAVACGVGPSLRVLQ
KRALDVGKLLLPYEPTELAAELAAKKAADPDFPIEQAHLFPLGGIKTCATWASDHGGASA
LPAARAV
>A0A842XV17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MFRERLKENVTPITYEVWSPKGCEVNRHLEAVSKFKDKLDAVNVPDNPLSTLRVSSVAYA
KIVMDHLKIDAIPHINCRDRNLLALQSDILGAHLLGIRNLFIIRGDKPLGRQEKAKGVWE
VTSAELCKIVKSLNEGFAYYNERLIKINGKTDFSVGGAIVFDRKNEVKIISKKIEAGFDF
FQSQITFNHETVLNFFQEAEKEGLIINKPVLVGLSPQPSEKALNNVLKFLHTKIPEQSLN
KLKRSDDFANELIMMCLEIADEVKSALSPRYKIGFHIMPLGCDDLGRKLVEELRR
>W2CUW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella sp. oral taxon BU063 isolate Cell 6/7/9|TrEMBL
MERVIDLINKSRGTAFSFEILPPLKGNSIQSVYRVIDKLRDFDPKYINITSHHSEAIEVR
GTDGMMRTVNLRKRPGSVAIASAIQNRYGIAAVPHLVCKGFTKDETEYGLIDLNFLGVNN
LLLLRGDVKRLHEPDNAELYHDHATDLQVQVNNFNRGIALDGSPITDIETPFSYGMACYP
EMHEDALSMDDDVRYAKLKVEQGAEYLVTQMFFDNAKYYAFVDRMRAEGVTVPIIPGIKP
IVLRDQLEVIPRIFHCTFPPEFAAALGRCRTDEEAKEVGVEWCTAQCRDLVAHGVPSIHF
YTLMASDSIRRVAKEIY
>A0A7C0Z0H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MRGEAYSELMKNLLEGKFVYTGELEPVKTTDLSEVIETAKLLKGYVVACNVTDNPTAFAY
MSPLVASYAIQKEAGMEAVYQITCRDRNRLAIVSDLLGAYYLGIRNVLALTGDHVSIGDN
PQAKPVFDLDSATLVYLIRKMVDEGVDLAGNEIEHPPKFHVGIAANPNANPLEPEILKIE
RKVKLGVDFIQTQCVYDIEVAKRFMDEVERFGVPVLIGISPFKSVAMMKWFVKFVPGIYV
PQEVQERILKAKQRGGKEAVYEESIEIFSEMIKEIKKTTKAAGIHMMAVGFEWIVPKILE
RVGVKVPESSE
>A0A497N7M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MAEERIFSNLMRELKAGKFVFTGELEPGKEGSIETTIEAARKLLGQVTACNVTDNPQSFG
CVNSLAAAFVVQKETGMECICQLRCSDKNRLALLSDVLAAGLLGIKNILAITGDYVSLGD
TPDVKPVYDLDSTLLTRMIRMIVDEGKDFRGNEIRNPPKLHVGVAANPGSEFLDMEVYKL
KRKVKAGAEFVQTQVVFLPEVVDRFFAKVKEVGGIDIPILIGIFPAKSYAEAKFFHEQVS
GVIVPEDYMAKLKETKEIKDKEKRKERIDQINIEYFTGFLEHLKSTPAAGCHIMAVGYPE
IIPELRKVVA
>A0A2A2T3E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vandammella animalimorsus|TrEMBL
MSASAPSQPQAPRAALSLEFFPPKTEAGALKLRATRQALYPLQPQFCSVTYGAGGSTQAG
TFAAVREILAEGQQAAAHFSCIGATREKLRAELAELQAMGVKRLVALRGDLPSGYGLGGE
FQYASDLVAFIREETGAHFHIEVAAYPEMHPQAASPEKDLQAFATKVHAGANSAITQYFF
NADAYFRFVDEARRLGLDLPIVPGIMPIHAASQLLRFSDACGAEVPRWVRSRLQAYGDDT
ASILAFGLDVVTQLCQRLLAAGAPGLHFYTMNQSTLVLEIARRLGLPTH
>A0A842SDY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MQKQRPAYSRLVKDIRKGKFVLTGELEPEKVTSLDEVLHSAKAMKPYVIAANVTDNPLAY
AYMNSLIPSWKVQEEVGLETVYQMTVRDRNRLALTSDILAASHLGIKNILAISGDHTVLG
DNRQANSVYDLDSAQFVYLLHKMIDEGEDLAGNEIHGDIDINIGIAANPNANPLMPEILK
IGRKTKIGSDFIQTQTMFDIDRTKEFLREMEKYNTPVLVGIFPLKGFTIADFFDKYIPGV
SVPKELMDNMYKAKQEPDSEIRKQKYDEVNIEFFKPFIKEIRKTTHAAGIHVMAVLYERI
FDPLLEAF
>A0A836SX60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenothermaceae bacterium|TrEMBL
MKISQLLRQVNRSISFEFFPPKTKDGEEALFKTIKELEHINPTFVSVTYGAGGSTRDRTR
NIVKKIHERTSLTVMAHLTCIGHTKKELLEILQDYKNIGIQNILALRGDIPVNMENFHIP
EDGCKFANELVGLIRVEFNDWFSIGVATYPEGHPESPNLERDVYYFKKKVEAGADFAITQ
MFFDNRYFYDYLELCEKEGIDIPIIPGIMPITNFKQIRKFALMCGATIPEPLVKKLEKVQ
DKNEEVEKIGIEFAVKQCEDLLENGVKGLHFYTLNKSKATIEIYNQIKHLI
>A0A5H2UN07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces tsukubensis|TrEMBL
MALGTASTRTDRARTVREVLATGQTSHSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVRATEQIASDTTLTPVAHLTAVNHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVRHPDGVTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVD
KCRAGADYAITQMFFRPADYLTLRDRVTAADCDTPIIPEIMPITSVGQLERFAQLSNAAV
PSELKERILAVKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYENLG
LHEQV
>A0A2A2AKG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vandammella animalimorsus|TrEMBL
MSASAPSHHPAPHAALSLEFFPPKTEAGAHKLRATRQALYPLQPQFCSVTYGAGGSTQAG
TFAAVREILAEGQQAAAHFSCIGATREKLRAELAELQAMGVKRLVALRGDLPSGYGLGGE
FQYASDLVAFIRAETGAHFHIEVAAYPEMHPQAASPEKDLQAFATKVRAGADSAITQYFF
NADAYFRFVDEARRLGLDLPIVPGIMPIHAASQLLRFSDACGAEVPRWVRSRLLAYGDDT
ASIQAFGLDVVTQLCQRLLAAGAPGLHFYTMNQSPLVLDIARRLGLLPH
>A0A7J4E488|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MVKEPISELTKELRSGKFVFTGEIEPVKTTSLHEVLETAKILKGHVVAANITDNPTAFAY
MNALVPSYMIQREVGLEAIYQMTTRDRNRLALTSDLLAAAALGIKNVLAITGDHTSVGDD
PRAKPVYDLDSASLVKLIRRMVDEGVDLNGNKIENPPKFHVGIAANPNADPLEPEILKIE
RKVKLGVDFIQTQAVYDIEIAKRFMEAVSHLKVPVLIGVAPFKSVAMMEWMVKFVPGIVV
PNWIQESVREAKRMGGKEAVYERNVEIFGELIKEIRKTTKARGIHLMAVGFEWVVPKIIE
RSGVMVRA
>A0A7J3VG46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MFYEHLHVSYPVTYEVVPPRGCSINHLEPIKEIQGYLSGVTITDNPMATMRISPIVYGSY
IREEFNVPIVPNLSCRDRNLLALQSELLGAHMLGFRDVFIITGDTPRKKNDFKGVWEVKS
KELCRIVKGLNNGTAKDKGYSRNLETPTDFNIGGAIVLGRPNEADTFKSKIDSGFDFFIT
QITYDPNEIIDFISTVGDETYPPIQVGLAPVASAKRFKTISRMPGINISEDIKRRLCASD
DFESAMVSELSEMADVLKEEVDYPLGFHIMPIGSDELGCRLVKELQK
>A0A6G8BVG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diaphorobacter sp. HDW4B|TrEMBL
MSQEQAQSKLPVSFEFFPPKTPEGAQKLRGVRAQLYERKPEFCSVTYGAGGSTQEGTFNA
VREILAEGVDAASHFSCIGATRDSVREQLALLKTMGVRRLVALRGDLPSGYGIGGEFHYA
SDLVSFIREETGDYFHIEVAAYPEVHPQARSADADLKAYVTKVKAGANSAITQYFFNADA
YFRFVDDTRKLGVDVPVVPGIMPITGASQLMRFSDACGAEIPRWIRLRLQGYGDDMDSIR
AFGLDVIANLCEQLIKGGVPSIHFYTMNQSAATLAICKRIGI
>A0A2S9HY71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. MYb56|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7C3XJK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
ALGIKNVLALSGDHTTVGDDPRAKPVYDIDSTNLVELLSRMVDDGTDLKGNKIDHPPKFN
IGIAGNPNADPLEPEIMKIERKIGLGADFIQTQAVYDLDLAKKFLEETSKFNVPVIIGIA
PFKSMSMMEWMVKNVPGIVVPEELQHRLKSAREKGGKEGFLNENIEIFGELVKNLRGMPG
VRGIHIMTIGFEWVIPKIIERANQ
>A0A515Y5P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. RLB3-6|TrEMBL
MALGSASTRTDRARTVRDMLGTGKATYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDVDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCTTPVIPEVMPVTSVKMLERLPKLSNASF
PDVLKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A3D3GFI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionales bacterium|TrEMBL
MTALPFRPDCKVTDFLKQHRFTRSAEIIPPRNGSEQRKVFEQIEILKNAGAQFLAVTKGA
GGSLRGGSLPIAQAIKETFSIPTIAHFTCRDLLPAEVESHLIDHHYFGIRNILALRGDPA
DGQAQWEPRAGGYNFAHELISQIKALNQGTFMPRPGGPEQIGHETTDFCIGAAVYPEFPD
ATKRIDYFHAKVAAGAHFGITDMLFDAEAYARFLDQCSARGIQVPILPGTRILKSRKQAE
KMMHKFKVSIPHDYLNALPGELATDAGPDGLKRGVELFLKLSERLERLGAPGIHLFVISD
TSIAVLGLKELAGI
>A0A1Q9U799|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. CNU-125|TrEMBL
MRPVRPERPPTVRELLATGGRSFSFEFLPPKTEKGTRNLWRTIRELEPLQPTFVSVTYGA
GGGTRDTTVDIVEHIATDTTLTPVAHFCAVNHSQAELRHLIGRLAAAGVRNMLALRGDPP
GDPMGEWIKHPDGVEYAADLVRLIRATGDFSVGVAAFPYKHPRSPDIESDTRYFVEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDIPIIPGIMPVTQISTIERSEQLSGAPFPPEV
KARFDAVADDPEAVRRLGIEHAAELSRELLDQGAPGVHFITFNKSTATREVYGLLEADGY
CDRTPLAGGAASGSVPPMTA
>Q1IYQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus geothermalis (strain DSM 11300 / AG-3a)|TrEMBL
MTRISIELVPRSRSGLRADLEVVARHLPGVCTVNVPDLTRFSTRSWIGCAFARPRYRAIP
HIRAVDLNPAEALPMAEALDAAGIDEVLIITGDAPADMSAQVHDVDAVRAIRRFRRELPH
VRIYAGLDPYRQSFARERDYLERKLDAGACGFFTQPFFDLRLMEAYADLIPEGAEVWWGA
TSVTSDATLNYWRARNHAVFPRNFTPTLEWNRTFAAQALAFARERGQHMYFMPVKADVRA
YLEGIV
>A0A251X1V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marivivens niveibacter|TrEMBL
MSRPNVSFEFFPPKSLDQSFRLWNCATTLAPLDPTFVSVTYGAGGTTRQLTHEAVGAIHK
NIGLTVAAHLTCVEATRAETLDIANAYADAGVTEIVALRGDPPKGSNGFAPAADGFQSSV
ELIEALADTGKFKIRVGAYPEQHPESANAAADVEWLKRKLDAGAHSAITQFFFEADTFFR
FRDACEKAGIDAPVIPGILPIENWNGAKKFANMCGTSIPQVVSDAFENAAKTGDTDLLAT
ALATELCDDLIRGGVNDLHFYTLNKPELTRDVCHALGVTPAAKLENVA
>A0A0M1J3Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromatium sp. WMS3|TrEMBL
AHTAQLDLQHFQRKVQAGANAAITQYFYNADAYFAFRDECTRLNIEVPIIPGIMPIINYT
QLARFSDACGAEIPRWIRKRLESYKDDLSAIRAFGHQVVTNLCQQLLDGEAPGLHFYTMN
QANSTLNIWKDLGLKNN
>A0A261T2I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella genomosp. 5|TrEMBL
MTQTTPPALSLEFFPPRDIAAQERLVRAAKQLLAMQPKYVSVTFGAGGSTREGTADTVRT
LSNLGCDAAPHLSCIGATRDQLREILARYRAEGIKRVVALRGDLPSGMGGDAGELRYASD
LVRFIREETGDWFHIEVAAYPEMHPQAVSPTVDLDHFVTKVQAGANAAITQYFFNADAYF
DFVDRARARGVTVPIVPGIMPITNYSQLSRFSEMCGAELPRWIRLRLAEFGDDKASIRAF
GAEVVTELCQTLLDNGAPGLHFYTLNQGDATLSIWKNLDL
>A0A3R8XBS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. p106|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAGCNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKDELRALLAQYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFETDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLAIWNNLKLPR
>A0A1V6FK56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin080|TrEMBL
MTIKDILESKKVSFSLEIFPPKKGTALSGAKTLIKDLALLNPSYMSVTYGSTGDNSDNTI
EMAKEVQCVNGITALAHLTCVSSDKQKVRDVLDGLKGCGIENVLALRGDIPEGLNFPIPG
GYRYASDLIKEIREMSCFCVGGACYPEGHPESKSVDEDIDNIKKKVESGCQFLTTQMFFD
NNILYNYMYKLLRRGINVPIVAGIMPITNVKQCERICGINGTALPQNFRAIISRFSDDPI
SLKQAGIAYATSQIVDLLANGFKNIHLYTMNKPDVAIKIKENICSMLD
>A0A520YW46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Brocadia sp. BROELEC01|TrEMBL
MKSGSNLEKILRSGQFAVTAELGPPRGADRSAIEKKTELLKGYGDAFNITDCQTAVVRMS
SIAAGRIVLDAGLEPIIQMTCRDRNRIAIQSDLLGAAALGAKNLLCLTGDHQKFGDHPMA
KGVFDIDSIQLIHMVKTLRDESKFQSGQELKTAGPRFFIGAAENPFADPFKFRAIRLAKK
IAAGADFIQTQIIYNTKKFKEWMKMVADMGLHEKAFILAGVAPLKSVGMARHMKHNVPGM
DVSDEIINRMTTASAAKKGKEEGIRICLEVIEQVREVKGVAGVHIMAVEWEEAVREIVQQ
AQLYPRPGQENL
>A0A2D7D223|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinovum sp|TrEMBL
MALFGLKTKHSQAPQVSQNLELFLKNFSIEVMPRTAEKVENFKDILPKNTRVYIAHIEGT
PIEDMVDTARRLAEDGFPTMPHFPARIISNKAMLNDWITRYQGEAGVDQALLLAGGVSKP
HGEYKSSMELLETGLFDKANFKNIHIAGHPEGNKDIDPDGSRKNVDAALKWKQNFKNKTN
AKMAIATQFAFEAGPIIEWAKSIKAAGIDIPIHIGIAGPAKLQTLIKFAIACGVGPSLKV
LQKRATDVTKLLLPYEPAEVLSQLADYKANNPEFNISSVHFFPLGGIKTNAKWVTENGGA
SGIPANQV
>A0A4V2F4B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Motilibacter rhizosphaerae|TrEMBL
MTTDPTVRDRIARGRFVSVELLPPRTPAGEEALAAALRELAPVHPAFVAVTYGAAGSDRG
RTEALVEQLAGTDVLPLPHLTCAAHRRTELVGILDRYIAAGVTSLLALHGDPPLTATEPL
PPGELRYAVELARLARDRGIPCVGVAVHPEGHPAADTREQDLDHQAAKLREADFALTQFV
NRAEDYLGFVDEMAARGVTTPVVPGLRVISTVQQAEKMALMSGAPVPQELLDRLRAVDGD
REAGRAVGVAHTTRVARELLAGGAPGLHFYTMNRATGTLEVLAGLDRA
>A0A4P5UGL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonadaceae bacterium|TrEMBL
MKAQKTLCSTFSFEFFPPQTSEGIERLRSARQQLAKLRPKFFSVTFGAGGSTQNRTLETI
LEIQAEGYVGAPHLSCVGSTNENIRITLQKYRDNGIRRIVALRGDLPSGMVQTGEFRYAS
ELVTFIRKEFNDMFHIEVAAYPEYHPQARSVEADLFNFKRKVEAGANSAITQYFYNADAY
FNFMDACEKMGVSIPIVPGIMPINRFPQLARFSDACGTEIPRWIRKKIEGYGDDSASIRA
FGLDVVTDLCDRLLKAGAPGLHFYTLNSAELTTTIWQRLKL
>A0A1V1UYE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. SH203|TrEMBL
MASPASLNLADARALLLSPLGPVARAGSNRDDVRVSFEFFPPKTDEAEANLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIITETSLRPAAHLTCVEASREEVDEVIEGYKAIG
VDHIVALRGDPPGASGIGGAYRPRADGYANATELTAAIKRIGGFDVTVGAYPERHPESPS
IDHDIEVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLK
RMCGACGTSIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETAAAQ
>A0A7C2E664|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MSGQVPESFQARLERGPLLADGAMGTMLYARGVPFDQCFDALNVERPELVRAIHEEYLAA
GAELIETNTFGANRFKLALHGLEDRVREINLTGAAVARQAREAAGRWVWIAGSMGPIGRP
LAPLGAVKPAEARQAFAEQARALEEGGVDVLIFETFSDLQELAEGVAAAREVTALPVIAQ
MTFTHEGRTLLGHTPGEIVARLEALGAAVIGANCSVGSQGVLEVMEQMVLVSRTPLSAMP
NAGFPAYVDGRILYFSTPQYMADYARQMVELGVSVVGGCCGTTPEHIRAMREVLRTVSPP
PPPRLRPRVTIPAAPPPPRPTPTALAARLGHRLVLSVEVAPPRGTQEGPELEACRLLRQA
GADAINVPDNPMARLRMSPWAMSLRIQADARMETILHFTTRDRTLLRMQSDLLALHALGI
RNILVLRGDPPQLGDYPSATSVSDVKPSGLIRLVKQFNEGRDLAGGELGQATTFLVGAAL
NMGARDLDRELRALEAKLRAGVDFLCTMPIFEPATLDRVLDRVGTLPVPLLVGILPLHGL
RHAEFLHNEVPGMSIPAALRDAFRQASRDSRELGLRLAEELVAAVRPRVQGFYLIPSFGR
YDRVLHLVQVLRREAPTPLDP
>A0A7C6GR30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MRIIDLYKKKPVISLEIFPPKPGTPLDGVFATIDALSVLRPDFISVTYGAAGGSKAYTVQ
IADTIKNKYGIEALAHLTCINSSREEVGEVLGQLQKAKVENVLALRGDRPEKESPDAPLL
SDFTYAADLIAYIKATGGFCIGAACYPEVHTEAENALTDLLNLRRKVKAGVDFLITQLFL
DNNLFYAFREKLALMEVKTPVSAGIMPVINKKQIERITSLCGASIPPKFRRILDKYEDNP
EALKEAGIAYATEQIIDLLSSGVDGIHLYTMNRPEVAKKIFSQIAGIRKHLKAEA
>A0A6B8JU37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spiribacter sp. 2438|TrEMBL
MKTILEAVPPELHRGDEAIEAVMDKVARVHAEWPLDGVNVPEIHEEPARSSKGERRQPFA
PRVAPRDLAWMIRERLGIECMINHVVVHEPAARLLDWCRQTWEEYGIRQFVLVGGGRAGV
RYPGPSVTEANQRVRDEAAIPGLRIGNICIPSRTDEAARMGDKVAAGADFFTTQILYEAD
DFTALLDELHEQNAAPAELLLAFCPIRRARNLRFLLWLGVNVPDALEAWLTENEAEVPAR
SLQQIRNTWDRITAHQHRQERQRPALGVNLAPIGAIPPAVTVGLLGDLAERADAPGEARA
>A0A6N3BCC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor plautii|TrEMBL
MMDIRTYLSQGKPLLFDGAMGTYFAAHPGRAEERCERANLTRPEEILRIHRAYLQAGCRA
IKTNTFAISGDLSDGNDETACDIVNAACRLARQAAQPYGAYVFADLGPAPRDHSRAPADL
YQTQAQWFLEQGVTHFLVETLSGDEGLPELAGWLKGKNPDAFLMVSFAVDHSGMTSAGRL
GSELYRFASELAGVDAVGFNCVSGPRHLLKYIQTLELSDKPLTVMPNAGYPTVLGRRTVF
GGQPDYFAGQIAQIVQAGASIVGGCCGTTPEHIAQTAQALKEPLPKCTVSAPKKLLKPAA
NASNSLWEKLEAGKRVIAVELDPPVDDDSAGFWEGVQALRGSGADAVTIADCPIGRPRAD
SSLLACKIKRDIGIEPLPHMTCRDRNLNATKALLLGLSMEGVHNVLVVTGDPIPTEDRNE
VKSVFNFNSRKLARFVHMLNENTLRTPFRIYGALNLNARNFDVELRRAQEKEACGVSGFL
TQPVLSAEALDNLKLAHKTLRGKILGGIFPVVSHRNACFLNNEISGMRVCDEIIHLYEGK
DRDAAEALAVTVSTAIAKEIFPYTDGYYLMTPFRRVALMEHIIQNIQQSCIS
>A0A7C6VD16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MRLREALASGKVVITAEVAPPKGTDLTAFRESLPYLKGRVDAVNVTDFQSAVVRASSLTL
CHLLLEEGLEPVLQITGRDRNRIAIQGELLGAAILGIENVLAITGDHTEIGDDPGAKPVF
DLDAVTILQAAKSLSQGRDLAGNPLQGAPDFTLGATVTPCYEPLELQVLKMESKLAAGAT
FFQTQAVYEVEVMRRFREATAHLGDVKVLVGIIPLKSAGMARFMNKNVPGIRVPEELIEG
IEEAPDPVAAGVEAAGELMAALLEEGLCDGFHLMTLGREDLVPGILAAAGLA
>A0A1C0VJK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillatoriales cyanobacterium USR001|TrEMBL
MNRFRTACKTPGEFIITAEIMPPKGGDPSHMIKMAQTLKNRVHAVNITDGSRAVLRMCPL
AASVILLQHEIEPICQVACRDRNQIGIQADLMGAQALGIRNILALTGDPVKAGDHPKAKS
VFDLEAVRLLQLIQKMNSGTDWNDKPLTDGITDLFAGAAVDPQSSSWSGLQSRFEKKLAA
GAEFFQSQLISDFDILEKFMTQIAAGCNKPILAGIFLLKSAKNAEFINKYVPGVNIPQHI
IDRLANSSDHLAEGMKIAAEQIQLARQICQGVHVMAVKREDLIPQILDLAEIPPLTVL
>A0A329KUK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium colombiense|TrEMBL
MAADSGCPKRMEFGPCGGVRPDGQCEMQPGPCVFDDVVPWSGHRPSPRPARAPRVLTDFS
ATPFDPDDIAATATVLAPGCDAVLVGEHQNKPDFPPTLMASLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSIDVETVLCVTGDGRGYDVRPDVSQTFDLDGPRLVSLAASVGIVAAVP
ETPTAPPVHRRPARLVEKQRAGASLAVLNHVPFPDMIADFMKSARAAGLAIPVIAAVAVF
TDSISAAVLEGLPGLELDPTVTQRVLSASDPVEAGIAAAVDEARSLLSIEGVEGVNISGL
ASASGPRIGAEIKAEVGRRIRDQGGGAP
>A0A357CBV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MARLLNRLTQGQFVVTVEIDPPRGPDAAKTLEKVRGFADRVDAVNVADCPMANVRMSPIT
LAHLIQRDAGVEAIFHLTCRDRNTIGLQAELLGAAGLGVRNILALRGDEPTRGDHPSATG
VFEIGSSRLIKLASTLNAGSTIGGSGLDCGTDFTIGCVANPNAEDLEAEVDRLEAKIAAG
AHFAQTQPVFDLRILEHWLMKVAGRVRIPILYGVMPLRNYEFAVHLNNDVPGITVPEWAV
ERMRVRGPQAGMEMVREFISSASAASEISGIHIFPMNNAARILKVVDIIDELGLRCQRKA
KPIRIETRD
>A0A373MQ86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF32-2AC|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPD
AMKQAGIAYATDQIIDLLANGVNNIHIYSMNKPEIAVAIMNNLSEIIKC
>A0A523A0Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
GGEFHHASDLIAFIRAETGPQLRIHAACYPETHPQARTPDADLQAFAAKMRAGADDAITQ
MFFNADAYFRFVDEARRLGVDAPIVPGIMPITNSSGLLRFAEACGCEIPRWIALRLQSFG
DDGAAIRAFGLDVITALCERLRSAGVPGLHFYTMNQAAATLEICQRLGL
>A0A450YSB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. TC|TrEMBL
MHLSGSIPRVFSFEFFPPKTLKGRNTLRATWRRLSELDPDFFSVTFGAGGSTQAGTMETV
LEIQRDSSIDAAPHLSCIGSTRVKIRNILEHYLSNGIGRIVALRGDFPPDMVELGEFRHA
NELVAFIRAEVGDDPRIEVAAYPEFHPTALSASADLENFKRKVDAGANSAITQYFFNKDA
YLRFVDSCQRIGVHIPIVPGIMPITNYVSLAGFSERCGAEIPRWLNWRLQEFGDDMKSLR
EFGVDVVTELCQGLLDAGAPGLHFYVLNRAEPVMTIWKNLGLSETRGSR
>A0A7Y8L600|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MTFQERLQENKFCITCEINPPKGSDAAERLEDAEALKGRVDAVAVTDGKGSVMAMNPLVM
SHLLQRKGFETLLHVSCRDRNRMALQSDLLGAAALGIGNLVVATGDYASLGDHPQTKPVF
DLDAVQLLKAVQKMESGQDLGGNPLHGRPKFFAGATVSPNPGREAALELQLLRMEKKIAA
GAKFFLTQPVFDVQAFARFMKRAASFGVPVLAGVLPLKSASMARFINKNLPGVFVPEALI
EEIGSAPDRVKASLTQCSRLVQELRGMCQGIHFIPAGWERKVPVILGAVRL
>A0A2H6JNJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Bbin14|TrEMBL
MKPDFVEYLKDHVVLGDGALGSYLYEKGIERGRNLDLLNLQAADFVFSAHEEYIRAGSQL
IETNTFGANHFRLREVGAQHRVGEINRAGAGIAVKAAGHQVYVAGSVGPTGLTFPLDEDE
VREEDIRQAFNEQIAALVEGGVDLIMLETFPCLDEILPAIAAARAVAPHLPLVAQMVFPA
RGMTVRGEDALTCGRAMAAAGADVVGTNCGRGIDAMATAVRRLAPLAKEGVILSAFPNAG
MPEMVGHRMIYPAQPAYMAMRSGEMIRYGVHLLGGCCGTGPEHIHEFRSTLKIRPVRIPG
GRLVVAPDKTPETAVAVRTGGFLAGLQTNRLPIIVELDPPTHLDVAPVLAGARALTEAGV
DAISLGDNPLATLRVGNLGVASLMRKETGIQTIIHQSGRDLNALALQARMMEAHLLGIEA
VLAVSGDSASATDQPEVSGVFDLRSYGLLRMLRQLNGGLNMAGRSIKHKTNFSVGAAFSF
RPDNPQLQISRLEKKFELGARFAMTQPLFSREAVERMMDKTSHLDMLIFPGIFPIISARN
AEFLHNEVPGMSVPAEFRRQLASYPGVPDQRKAALDYTRQLVEDIAPIVDGFYFVSPLNK
WDIALEFVRQVRQAGWQGSGRATP
>A0A1V4DV68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbispora sp. GKU 823|TrEMBL
MALGLPSRLPDRVPTVRELLAAGERSFSFEFMPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPRGGNPLDEWVKHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSATIESDTRYFV
QKCRAGADYAITQMFFRAEDYLRLRDRVAAHGCDTPIIPGIMPVTQMSTIARSEQLSGAP
FPPEVAERFEAVADDPAAVRRLGIEHAVELCQKLLDEGAPGIHFITFNRSSATREVFQAL
HSVPAAVAG
>A0A800BQ78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MGFREALDSGKFVVTAEIGPVKGTEVEGILENAQILKGRVDAINVTDLQSSVMRLGSMAV
CHLLIDHGLEPIFQLTCRDRNRLALQSDLLSAWVLGIRNVLALTGDHPTLGDHPQAMPVF
DLDSVSLLRVIRRLNEGLDMMGNQLKGSTDFFPGAVVNPGADSEAAFEMQIIKMEKKIME
GARFFQTQGVYDLDVFKKFMRRVEGFRVPVLAGIILLKSAGMARFMNKNVAGVFVPEPLI
KKMEETKDKVKTSIQIAAGLVKGLKDLCQGVHIMAIGWEKRVPAVLEEAGL
>A0A2N2MDX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-6|TrEMBL
MRISNILQENKVHFSFEFFPPKTEEASHTLFETISELSPMQPSFVSVTYGAGGSTNELTQ
NLVIRLKRETPLNVVAHITAIGASREEIKSQLESYAAAGVRNVLALRGDPPKGSTSFTPT
SDGFRYAAEMVAFIKKHFPHFGVSVAGFPEGHPETPNRLQEMDYLKAKVDAGADCICTQL
FFDNHDFYDFCERCELAGIKVPIIAGIMPVASLHGLKRMSELALGARIPAKLLRAVLRAQ
SGEAIEKIGIHWATEQVFDLYDHNVSGIHFYTLNHSTATLKIYETLGMSLGETWHAPTPH
KSKNQPG
>A0A445N732|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces netropsis|TrEMBL
MRELLARGERSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSVTYGAGGSSREGTVRA
TERIATDTTLTPVAHLTAVNHSTAELRNVIGQYADVGIRNMLALRGDPPGDPMGEWVRHP
KGIDYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADFAITQMFF
YPEDYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFAQLSNAAFPPDLAERILAVKDDP
AAVRSIGIEYATQLCTRLMAEEIPGLHFITLNHSTATLEIYENLGLHQRS
>A0A0D0QQE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium TWA4|TrEMBL
MRITELFDKGEFVVTAEVGPPKGFHIEKMVEEAKEYLSDLSAVNITDNQSSVMRLGSLAT
CKTLKDAGLNPIFQMTCRDRNRLALQSDLLSAAHFGIDNILCLTGDYTTLGDHPTAKPVF
DLDAVSLLHTVRCLEEGHDLAGNELDGEPPKFAKGAVVSPCSDSVDAQLAKMERKVMAGC
DYFQTQGVYEPDKFAEFMEKAKQFGKPVQLGIIIPKNVGMLRFMNANVAGVHAPESLIEE
LKADKEKTKAGITGVEISARLIRECKPYCQGVHIMSLGWENKIPDILKLAGLTK
>A0A101VA10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium BRH_c42|TrEMBL
MAAPLIHPNWARPPIGITEGYSLEITAKDVAALREAAPLIPADTPVAITFLPGEEAHARV
AAAVAVRELGFEPMPHFSARRIVSHDEFESYLAAVAREAEVRRCFIVAGDPPEPQGPFFD
TSALIATGAFERAGIKAIGVGGHPEGHPVMSRQQCWDVLECKLADIERRGMAPLVVTQFG
FDPDAFLAWLKEARLRGIDTPVRIGIPGPAGIKTLLRFAARCGVGASASVMMKYGASITN
LLGSAGPDRLVDAYAANLGEEHGRVRLHFYPFGGIGRTIRWIVDYNELHG
>A0A3D2XXN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPGNEKMENTLWKSVERLAPLNPAYMSVTYGA
NSGERDRTHDVVKRIQQQTGVTAAPHLTCVDATADELRQIARDYWDSGIRRIVALRGDLP
KGVEKTDMYASDLVALLKEVHDFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTGVFLRFRDRAAAAGIDLDIVPGIL
>A0A239QBZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. CC120222-04|TrEMBL
MPAPGSQRAEAFINTFSLEVSTKAMPSLRAEADRIPRGTTISIPYLASEDDDARLAAART
VRALGFEPMPHLSARRIGSHAAFEGFMERAASEAGVEQCLVIAGDLATPAGPFADSASII
ETGLLERFGIKVVGIGGHPEGHPVMSSDDRWQALERKCRAIESRGMAPLIITQFAFDADI
VLAWLNILRARGINVPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGVSIGRLLGTA
GPEVFVDQLVSGLTTGHGQVSPHFFPFGGIAPSLDWIERYRRRTSAASV
>A0A4U1BI66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrimonas sediminicola|TrEMBL
MGFHHAQQLEALNERLSHLKDIQVSFEFFPPATEEMEQTLWGSIERLRPLRPRFVSVTYG
ANSGVRDRTHKVIEKIHRQTDLVAAPHLTVVDASEEELRGLANQYWQQGVRHIVALRGDL
PEGQGRPDRFAVDLVKLLKEEHDFEISVAAYPEVHPEASSAQADLINLKRKVDAGANRAI
TQFFYDIEAYLRFRDRCAAAGIDVEIVPGILPVTNYRQLLKFAGFTNVHVPNWLHHMFDG
LDDDPATRKLVGANVAIEMAKVLAKEGVREFHFYTLNRAELSYAICHALGVRP
>R5JJI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. CAG:782|TrEMBL
MKIIDIINQDRPTLSFEVFPPKKDTDFADVEAAACSIAAYKPDYMSVTYGAGGSTKGHTI
RLAKEIQEKYNVPTIAHLTCVCADKETIRKALTEMKDAGIENILALRGDVPKNYEGEVFT
DFVHASELVRLIKETGDFCVGGACYPEVHPDSANKKADIEGLKKKVEAGCEYLTTQMFFD
NTIFFNFMYRLRTAGVMVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKSIVDAFGDTEA
AMRQAGIAYATDQIIDLMANGVKHVHVYSMNKPDVAYGIQKNLSEILKA
>A0A5S5MFW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobotulus mexicanus|TrEMBL
MLLSDIFEKNPMTFSFEFFPPATEKGWESLFHTIADLMPLEPAYVSVTYGAGGSTRDRTH
KLLARIHRETPLTAVSHLTCVGASKDEIHEILSAYDALGVHNILALRGDPPAGEPFTPHP
DGFLYAADLVAYIKKHFPGMCVGVAGFPEGHPATPNRLLEIDYLKAKVDAGADYIVTQLF
FDNRDFYDFQDRCQLAGIDVPILAGIMPVTTRKGMERMAELAAGARIPAPLLRAVYRAES
DAMVENVGVHWATEQVRDLIDHGVRGIHFYTLNRSPATLRIYEALGVKNSRNLSR
>B6B833|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium Y4I|TrEMBL
MMDHSLPQPYSPPPEGHVSHSRLERVLRSGRFAITAELNPPDSADPADVYDAARPLGEVA
DAINATDASGANCHMSSIGISALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAAMGVSNV
LCLTGDGVGVGDQPGAKPVFDFDSLSLLRTIRTMRDERKFLSGRTITNPPLLFLGAAENP
CIPPYEWRPERLAKKVEAGAEYIQTNYIYDVPLFEKFMARVRDMGLDKKVFILAGVGPLA
SARAARWMRSNVPGIHIPDAVIDRMEKADKPGQEGKKICVELIQQMREIAGVSGVHVMAY
RKEHQVSEIIQESGVLASRKRT
>A0A2D7GQV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVSAVPHLTCVDASREELKQIAQDYWDSGIRRIVALRGDLP
AGVDTTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIS
QFFFDTSVFLRFRDRAAAAGVDLDLVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRGDNK
>A0A523SI03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Cloacimonetes bacterium|TrEMBL
MELAKYLERNYIIADGAMGTTLYKKGFSSKKPFAMVNIDNPGLVMEIHTEFVEAGVELLV
TNTFDANIFKLDPYVDFKGIREVNKKGAELAKKVAGDRKWVAGSVGPSGKTFSLLEQDEK
EWFKESLIEQVEGLIDGGVDVLLVETQIGINEALFTIDSIEKNRKGVPIIISFSFTEGLR
TPSGETVERVIDASKDLSLLGIGANHGIGPLQFLELMPLFLEKTNAPVCFMPNSGVPRYI
DGTFVFPASSEHFARYAREFIKKGIKIVGGCCGTTPDYIHLLVSMLKSTSGRSLHFLFVE
EEEVETQEIAVKEKVKNIVEEQINSKSLVVVEVSPPKGAYIKKSISWIEKIKEFGVDAVS
ILDSPMARVRMNPVAFSHLVKERGLESIPHFALRDRSLTRIQSDLIAACALGLNNIFAIS
GDPPSLGDYPQSTAVYDITSPGLIKLIKLLNTGKDFAGNEYTNPTSFYVGAAINPSPPDL
EKEIAKINEKIEVGTDYFVTQPLFDSKTLFGFTEKVNLKNIPLVLNIFIPRSKKQFEYIA
HEVPGIQVPENIMKMVEEKEDWLSFLQDELVKVLVELKPIISGLYVAVPRGRTAYLRPFM
EEIKGKKWGL
>A0A2H5KGJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus caldolyticus|TrEMBL
MGLLDELKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGGAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEEAAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRAASVS
VQADRPAPTPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIVKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDVSSFDLIRLISQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPVYSEEKIVQIYEATKHLATPIYIGIMPLVSARNAEFLHHEVPGIT
LSDEIRARMAACSGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A7H1ME15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria musculi|TrEMBL
MLNSKQRKKLSFEFFPTRTPEGRAKQVITRKQLSQFDPEFFSCTSGAGGSTKDGTMQAVQ
DILNEGVAAAPHLPCVGMQPHEITALLNGYKSLGVHHIVALRGDIPSGMGAGLDGLRYAN
ELVSLIKTEFGNDFHIEVAAYPEYHPQSRSAEDDLNNFVRKVKAGADSAITQYFYNADAY
FRFLDDVHGRGVDIPIIPGIMPIASFSKLARFSDTCGAEIPRWLRLKLQSYADDTASIKA
LALDVVTDMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>A0A8E4F7A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter terrae|TrEMBL
MSQLSTCFTQNQFCVLVEYLCSMKEILPVKTEFAGFPALMTLADRVHSDDDLAPLLAAQA
YPKSVEKVLHFAGKGRDIADFEHFLNEAKGVGQQNLLLLTGDKLKSHQYGQDDATKRTRY
LESVNAVMAAKQRDSFCIGVAFNPFKYAEAERDAQYFKLHKKMKAGADYIITQLGYDLSA
LKEAKAFLTQHGYPQKLLACVMPLTLARANFMVKHQVAGIVITPHMLNVLREEKEAGLMD
RVYLRCALQILICKHLGLAGIHLSACHKLEEQMLLESYIEEYRHLDLAELELLWNTLWQV
KTGQEFYPALTYYSRPASATQILKYQHLHFMHDALFESKVAKGVGRFIFQSRFWNGTLAA
QALLKTEFVSKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDREC
IHSVKARLAKAVNQTKILKDNLIPTVPIEVRGSSSWKNWYLKKAV
>A0A1W9U674|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterium sp. 4572_20|TrEMBL
MKSGSNLERLLEKGEFVVTGELGPPKGTDVDVVKKKASMLKGNVDAVNITDNQTAIVRMS
SIAAAKVLIDEGLEPNMQMVARDRNRIAMMSDLFGANALGIRNMLCLSGDHQTFGNHPEA
KNVFDIDSIQMIYMVKTMRDEHKVICGDEIEGDFKMFIGAACNPFADPFRYRVHRLAKKV
EAGVDFIQTQCIYDMKRFKEFMKQVVDMGLHEKCKILAGVTPLKSVGMARYMAANVSGII
IPEEMIARLKGAGKGNVATEGIKILCEQMQELKETEGIAGIHLMAIEWEHRVPEIMEMAG
FLPRPKP
>F7RSK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. HN-41|TrEMBL
MAFHYAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETNLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPSWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPKVA
>A0A0N0JFN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. AAP1|TrEMBL
MAYAQIHPNWDKEPAGITDGYSLEMTAKDIASLREAAPLIPPETPVAVTYLPGEEAQARI
AATVAVRELGFEPMPHFSARRIIDVPEFEAYLKAVVEQAGVRRCFIVAGDPAEPQGPFFD
SSALIATGAFERAGITAIGIGGHPDGHPNMTEAECWAVLDKKVAEITARGMAPLIVTQFG
FDADSFLVWLEKLRARGIDAPVRIGVPGPAGIKRLLGFAARCGVGASASVMKKYGISLGN
LLGSAGPDKLVDAFASGLGPQHGRVRLHFYPFGGLAKTVEWIEDYRRRHPA
>A0A1U9Z4J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Martelella mediterranea DSM 17316|TrEMBL
MTDGTGALTRPIEYSFEFFPPKSEDAAAGWWRAVEALSAYGPAFVSVTYGAGASSQAPTF
DAVKRLIDETDLVTASHLTVVKATSSEVDNVIRRFRDAGVKRFVALRGDAPDGVGTAYRP
HPGGYANAAALVAGLKAIDDFDISVSAYPEKHPESADRAADIAMLKAKADNGADRALTQF
FFDNDVFEDYLNDVRRAGVTIPVLPGIMPVQNLNQLKRFAAMCGASIPDFLEKRLGNLVD
DPAAHFEVAADIAAEQVLDLQKRGISEFHFYTMNRSKLLIAVFDRLGIKPAESASDEKML
GRTG
>A0A5R1QZ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. BCA14|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAAQLATYHPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1V4S7W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4484_190.3|TrEMBL
MASRFKDALESGKFVVTSEVAPPKGTNLEKMKHHVDLLKDKVDGMNVTDHQSSVMRFPSL
GGALLVKEMGGEPILQMTCRDRNRLALQADLLFASNRGINNVLCLTGDSVILGDHKEAKS
VFDLDSSQLLATVRQLEKGRDLGGSDLDGAVSFCAGAIVTPEANPLEPQLIKFEKKVEAG
AEFIQTQAVYDLDHFKQFMEYARQFPVKVLAGIILLTSAPMARFMNKNVAGVTVPKELID
EMAAAPKGRAVDTGIMIAGRMIKRIRDEKMCDGVHIMAIGREELVPAIMEAGELL
>A0A0S8CH62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira bacterium SG8_3|TrEMBL
MSNLKKVLENGEFAVTGECGPPKGADPETVLKKAELLKDKVDAINVTDNQTAIVRMSSLA
ACSLLRSAGLDPVLQVVVRDRNRIALQSDILGASAVGIRNVLCLSGDHQGFGNQPQAMGV
FDLDSIQFVSVVKNMRDEGTILGGEPLSRPPELFIGAAANPFADPLSFRVIRLAKKINAG
ADFIQTQCVYNLKRFQEWMKMARDKGLTDKAFILGGVTPLKSPGMAKYMNNKVAGMDVPD
EIIKRMEGVSKEKQREEGIQICVETIQQLKEMPGVKGVHIMAIEWEEVVGEIVEKAGLLP
RPAFS
>A0A4Q8LVR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas winnipegensis|TrEMBL
MTQISFEFYPPKTDEQRAQLDRTAERLARYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFDAAPHLSCVGGSREEIRELLKLYRAIGCKRIVALRGDLPSGMGHAGDLRYASELIAFI
RAEHGDAFQLEVGAYPETHPQASDALSDLKHFKAKVDAGADAAITQYFYNADAYFGFVEA
VRRLGVEIPIIPGIMPIANFAQLRRFSEQCGAEIPRWIAKRMAAYGDDAAAVKDFGADVV
AQLCQRLIDGGAPSLHFYTLNLAKPTQTVLQRLGIR
>A0A140PUQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. animalis 7_1|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSLEKPDYISVTYGAGGNTKGKTV
EIADRIKRQNGVESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEKGD
FNYARELIEYIHKRKGDKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRK
>A0A8E2N8H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. AU28863|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DTRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAAVATRTICERLAV
>A0A257UFW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 21-70-11|TrEMBL
MRARARGRPGPHPATRGTGKQDSLHAVEEQGARPSGMPLAKTNLYNAEMDHARTVRRFAD
HVVVADGAMGSELLTRVPAGVHLDLAPLDYPRQVLEIHLAYLAAGAELIETATFAASRPR
LERLQAGDRVEALNSAGVKLAREAREIAGVDCLIAGSIGPLAGVIDLDERAGRSAIAGAH
AEQAAILAGRGADLLILETFFRLDELLLAIEAARGATDLPLVAMLTFPFERLPESHPELA
AQVRELLACDVLAAGVNCAPGPQGTLDIVECLADASRPLAVMPNAGSLVRRDGRIFFPPA
TPSYLAGFARRAAELGAGLVGGCCGTGPEHIRAMADAVRGMSPAHAHRAPVAVEERRVPA
PLPHPRPASSLAAKLAEGRFVRVVQLDPPRGTNSERIIEATRALAASGRVDAFDINSNPL
ARLRMESLWLGAEIQRATGIETVPHITPRDASLMGLQAQLLGAWHAGIRNLLAISGDPSQ
LGDYPGVHDVNHVDIFELVRSVARMAEGFDCAGNPIGEPPAYCLGVAVNPAADDLGHEVE
RLRRKADAGAHFAMTQVFFSWEPWERLLDRCGGALPLPALVAVWPLPSFRLALRLHNEVP
GIHVPEELLARLEAAGPDAGKVGTERALAMLAEAPRRAAGVYLVAPFKNPADVLGLLES
>A0A8E1QDR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae PID24-1|TrEMBL
MNYAKEMNALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRSVVDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A7Z9FBG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTDSDAGTLDDSRSTHSQGRLERLLRAGAFVVTAETTPPVSTDPAALLEVTEDLRDWADA
VNVTDSAGAKSHMASLVAASLLMRAGIEPVLQFTVRDRNRIALQNDLLGAGALGISNILC
LTGDNISAGDQPDAKMVMDLDSRGLVSLARDMRDSRQLPTGRPIGKAPNLFIGATDAPQE
PDNEWSATALQSKVDAGAEFFQTQFCFDIDLVRRYMQRLENEGVLERAYFLIGIGPIASA
KSARWMNQNLFGVDIPESIIGRLEQATNQQAEGRRVCLELIQQLREVAGVSGVHLMGPQA
ERSAAQVIADSGILNERPEVA
>A0A4S0GJ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1C.F.Ca.ET.192.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDDMEARLWDTVTRLEPLKPQFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIREFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVA
GSAAA
>A0A523F6X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSGTDDKGRASGGLALSFEVFPPKNDAQADQISKVAASLETFDPAFISVTYGAGGSTRER
SIATIHRLAGETSVPLAAHLTCVGASRRTLERVIDDIRSIGVERFVVLRGDSPDGIGAPY
RPHRDGYQDTADLVRHLKATGASDISVSAYPERHPDSPDWQADLDTLKRKVDAGANRAIT
QFFFDNDDYQSYVRRVRAAGLSIPIVPGILPIHNINAVRNFAARCGASLPETVLERFDGL
DPSTVEHRRTAVEIAQEQIEGLLARNVGAFHFYTLNRDNLVVPLCRWLQRSAPKSQPA
>A4QFN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium glutamicum (strain R)|TrEMBL
MVGVNKCQRQSQQNTFITLRYPGMSLTNIPASSQWAISDVLKRPSPGRVPFSVEFMPPRD
DAAEERLYRAAEVFHDLGASFVSVTYGAGGSTRERTSRIARRLAKQPLTTLVHLTLVNHT
REEMKAILREYLELGLTNLLALRGDPPGDPLGDWVSTDGGLNYASELIDLIKSTPEFREF
DLGIASFPEGHFRAKTLEEDTKYTLAKLRGGAEYSITQMFFDVEDYLRLRDRLVAADPIH
GAKPIIPGIMPITSLRSVRRQVELSGAQLPSQLEESLVRAANGNEEANKDEIRKVGIEYS
TNMAERLIAEGAEDLHFMTLNFTRATQEVLYNLGMAPAWGAEHGQDAVR
>A0A2R4CHB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia armeniaca|TrEMBL
MTDHNFSIEFFPPKTAEGAEKLRATRAKLSELHPKYFSVTFGAGGTTQQGTLDTVLEIMA
AGEEAAPHLSCVGGTRESIRAILQQYKAHGIRRLVALRGDLPSGYGAAGEFRYASELVEF
IRAETGDWFHIEVAAYPEVHPQAKSPQADLDAFVRKVNAGANAAITQYFYNADAYFQFVE
QAHKAGVTVPIVAGIMPITNTTQLMRFSDMCGAEIPRWVRLKLSSFGDDTASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQVAPTTALWQRLVK
>A0A359CE75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium|TrEMBL
LKEFDPKYINITTHHSESMYKEDAEGVYRKISVRKRPGSVAIAAAIQNKYGIKAIPHIIS
QGFSKEETEYALIDLSFLGVTDLLLLRGDTKNLDALQRNLDSHPHASGLQEQVNDFNRGV
SFDGSSLTPPEIPFSYGMACYPEKHEESPNMESELFYTKMKVQNGADYLVTQMFFDNRKY
FEFVDRCRAEGITVPIVPGIKPIHLKNQLTVLPRIFRSDLPEELAKALRTCQSDDEAKQG
>A0A5Q4F959|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneolaceae bacterium|TrEMBL
MKVTEHYDRASEPLISFEIIPPKRGGSIKTVFDALDKVVSTVKPPFIDVTYHAPEVQVEE
QSDGTLKKVVRRKRPGTIGLCAAILHRYGIDPVPHLLCGGFSRESAEDALIELNYLGIHN
VLALRGDDHGSEAPYPVGGSKNRYASDLVAQIQDMNQGNYLEKLAHAEPTDFCVGVAGYP
EKHFEAPNLDWDIKKLKEKVDAGAHYVVTQMFFDNSRFFDFVERCRDQGITVPIIPGLKI
LTTPNHLSSLPKFFHLNIPDALANSVEKDPKNTKSIGIEWAQKQCLELMEGGVPGIHFYV
MGDPQPALDVIRFATKK
>A0A543NHL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloactinospora alba|TrEMBL
MFGSPTSNETGRPAETRPRHIPDLLSAGEPTFSFEFFPPKTPEGEQKLWRSIRDIEALQP
SWVSVTYGAGGGTRDRTVEMTEQLATDTTLLPLAHMTAVNHSVSELRHLIGRFASAGVNN
MLALRGDPPGDPLGEWVKHPEGLEYASELVRLVKESGDFSVGVAAFPFKHPRSASVDEDT
DFLVRKFQAGADYAVTQMFFDAEDYLRLRDRVAAKGGGDTPIIPEIMPVLQHSTIEKSEQ
LSGAPFPKHLAEEFERVSDDPKAVRELGIDQATRMCERLLDEGAPGIHFITFNQSTATRE
IYERLSGSRVPAAAGART
>A0A0Q5J2C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. Leaf148|TrEMBL
MIDAKTPGVARTIASTITDAYSLEVSAKDTAGLAAAAPRIMRGATIAIPYLPNQDDDARL
AAARRVRTLGFQPMPHLSARRIASRDALHSFVSRAVDEAGVERCLVIAGDPPAPLGPFPD
SVSLIDTGVFERLGIQTIAVAGHPEGHPSMPAIDRWDVLEHKCRSITAHGMAPLIVTQFA
FDADIVLTWLQALRAHGIEHPVRVGVPGPAGVAVLARYAARCGVGACTAMLSTYGISLGK
LLGTAGPERFVDRLATGLTEAHGDVSLHFYPFGGIAQTVAWVERYRASIARVRAD
>A0A2E7I5U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MMASQADKPSVSFEFFPPKTLEMEKALWDALCDLAPLEPAFVSVTYGAGGTTRERTHATV
SRIVKETGLTVAAHLTCVDATREEIETVARGYWSEGVRHIVALRGDPPTGQTKYVPHTDG
YAYAADLVAALRAVAPFELSVAAYPETHPEAVSSDLDIDNLKRKVDAGAVRAITQFFFDN
DLFFRFRDRVVAAGVKIPLVPGIMPVGNFKNMMRFADTCGAGVPDLMAAAYEGLDDDPAA
RAEVGKRLASEQCLDLCSNGVNDFHFYTLNRSELTGAVCANLGVTGGGPEIDLK
>A0A537UTF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTSPQRQPASRLEELLRAGRFVITAEITPPVSCNADDLLRKALPLAGLADAVNVTDGASA
RAHLCAPIAAALLARAGIEPILQFTCRDRNRIALQADLMGAAACGVRNLLCLTGDD
>A0A1Z4V8M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dolichospermum compactum NIES-806|TrEMBL
MPDTYSFSAFNNFRTAAQKGDFLITAEVAPPKGGDPTHTIEMAATLKGRVHAVNITDGSR
AVMRMSSLVASVILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPQAKAVFDLEAVRLLQLIRNMNQGFDFNEKPLTDGALDLFAGAAVDPQSKSWSGLQS
RFEKKIAAGAQFFQSQLITDFDILEKFMNKIACGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEEGMKIAAEQVQIAQELCQGVHIMAVKREDLIAPILDLAGV
EKVS
>A0A3M1J1K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MLNALANDARPEGDLHVSFEFFPPKTEKMEEALWRAIRRLEPLGPDFVSVTYGAGGSTRD
RTHATLKRVLEETALKPAAHLTCVAATREEVDDVIRSYADIGIRHIVALRGDPVEGSGGV
YRPHPGGYETSADLIAGIRQIGD
>A0A2M7AF18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium CG07_land_8_20_14_0_80_59_28|TrEMBL
MSENNGYKSGSRLERILAAGQFAVTAELGPPKSVDVAVIEKKAGHLKNKVDAVNITDNQT
AVVRISSIAAGVLALQHGLEPVIQMTCRDRNRIAMQSDILGAYALGARNLLCLTGDHQSF
GNHPTARHVFDLDSIQLIQMVRIMRDEGKFLCGDEIRNSKKESVVEPRLFIGAAANPFGD
PFEYRVIRLAKKAKAGADFIQTQCIYDMPRFKEWMKQVVDRGLHEKLYILAGLTPLKSAR
MATYMRDSVAGLTVPDEYIERMEKAENGAEEGIQICIEQIQELRQVEGVAGIHLMAIEWE
HRVPEIMERAGLLPRPQVN
>A0A4P8SG38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nissabacter sp. SGAir0207|TrEMBL
MSFFHANQRDALNQSLSELQGQFNVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRQIARDYWESGIRHIVALRGD
LPPHGGKPEMYATDLVALLKEVGEFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPQWMTHMFE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGIRPAAVPAH
A
>A0A846AMB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO2C9|TrEMBL
MNRFRNAVKSGEFLVTAEVAPPKGADPTHMIEMASTLKGRVHAANVTDGSRAVLRMSSLA
ASIILKNNGIEPICQVACRDRNRIGLQADLMGASALGLNNILALTGDPVKAGDHKDARSV
FDMESVRLLQMIAKLNQGIDWNEKALPDGATDLFVGAAVDPQSPSWSGLKKRFERKLLAG
CQFFQSQLISDFDKLEKFMNQIAVESNKPILAGIFLLKSAKNAAFINKYVPGVDIPEHII
NRLAKADKPLEEGMKIAAEQVQIASKICHGVHLMAIKREDLIPRILDMAEISPI
>A0A519CXX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MDSGLDFLNKIHDRIPVSLEILPPNRGLGLDAIHSFFEGLKPWKPAFVSVTYHQAFKVEE
NESRIWNRKKPGTIGVCAMLKFQYGLKVIPHVICGGFSSFESEDFLVDLDYLGLDTILAL
RGDPKKGDAEFKHHRDGHRYASELVDQVMRLNMGEYMEDVKEAKSTSFVVGVAAYPEKHR
EAVSLDVDIQNLRNKVNAGASFIITQMFFDNQVYFDFVERARNAGITIPIIPGLKIITSK
RQVEILPEIFHTKMPADLCSIIQRCENDFEATEIGIKHAISQFKGLEEYGVPCIHLFSMN
NLTPITSLLKGVQRI
>A0A256Z194|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurococcales archaeon ex4484_42|TrEMBL
MRQCPKKVINGPCGGYRGALCEVNGECVFIKVLSSKNVKELRELFSSVILDERFKIKDYF
PVLRRPLTQFMKSLRRGDKLIIYEIFLNIGNDVGEILNDLKSIARPDVVYALTDSPLGVL
TFDPLALALMLKDHVNVLDFILNISMRNKTVENLVRYVVTATNMGLRNLLIVTGDWSKEF
ENSFTLDSTRAVYLLRLLCDLGLNINGEVLTVPQYIHLGVVSNPESDYTSIEVFKSIRKI
LAGAEFIITQPIYNVNRFKEYLKGLLNESIRDVPIIPAFAPIVSEEHLRIAESFGIKVYR
RDLIEVLRTGDMDAIINKNVELLQEIVDAVKDVKAVYLSTYGNLKLGKLFMNILRKVL
>A0A7C5BID8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MSKNVTTFSDLLQKRPLIFTVVPLRDNLTGDPKHDDNILKNLTAKKDEIVKALLPYSRLT
AVNVPELIEENHEGKPRFNSIYTRKLARSIADELKIDAVVNKVVVHIESYEDFVSWISET
SSLGITNIIFVGGNTRHHRYPGPTVSEANITARHLVQRHVISDVTVGNICLPERRDEAKK
MLFKTITGANFFTTQMIFDSSQISDVLIKYGKLCHQAGVRPATVLISFAPLKSTADLNLL
DFLGVDLPEDTKSRILEDVSIAEATRRSLVNAIRVYGEVLEKLEASDYPVPIGINIEQLT
KSNLASSVRMLEEFSRIIDMDSGKVMKYNGDAAEV
>A0A7J9Q4Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MVQQSSILEIMASKNFTFSAEVFPPRNGKSPTIIMEKLDALGGLGMDFISVTKGAMGSMR
GGTVPIGYMIPDRYGMNALVHFRCRDMNRREVENLLVDHMYFGTRNILAILGDPLPGEPA
NAINPETHHRYASELVKQISDMNSGLYLPMKQGGGPRGGMKTDFCIGVACYPEAEDMEKE
LFVMGEKVAAGADFAITQMVFDADDYAEYLDALRSRGIKIPIIPGIRPVSCMEHVETAEK
NFGVTVPESLKTRLKCSGGEADAICLGFTLELIHDLKAMGAPGVHMFTLNDTEIIRKIMG
AL
>A0A2D6VT36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MSNPSGGGAFLCLLRRQKNAVNVAFFESGCVMSAAEKLLESLYYEVIPMKGFEEKLDVLK
AGDRVGITCSPKQGLQVTLDTVAKLSDRGFSLTPHLAARQVMNKQHLSDIVSKLTDSGIT
SVFVPGGDLDEPMGEYDSSAAVLRDLAEMDHPFTRIGVASYPEGHPAISDDLLFEALSAK
QGIATHMVTQMCFDMRVLVKWLSEMRDRGITTPVWIGLPGVMDRMRLFKTSLRIGVGQSA
KYATKQKGLIGMFLRSPTYKPDSLFKALKPAMNDERMAIEGLYMFTFNQIDNTVQWSQEQ
IKRMR
>A0A1E9DST2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC062B01|TrEMBL
MVRHHTPSLSFEVFPPNPAVGNEKIIQALREMQDIAPHYISVTASNNKFNIEETTVRLAD
FIYNDLKIPTIAHLPAVYLTKEMVSDTLQALDKVGVHKILALRGDIFPDVAPKDDFKYAT
DLIEYIKEEAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDIPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGVHLYTMNNATTAHHIYQATHTFFS
>G1LTB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ailuropoda melanoleuca|TrEMBL
MDHPTPKVLPARPRGPSLGMWALEAGRVRFSVPPSISRNRAMVNEPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERHDRLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQITG
YLHKARRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFQFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQQLLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFAHYLS
GEPNQQGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPAPERETEAL
>A0A1M5KVN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas xanthomarina DSM 18231|TrEMBL
MSKPQSKPAISFEFFPTKTDAGHEKLMVTARRLAEYKPDFFSCTYGAGGSTRDRTLNTVL
QLDGEVKVPTAPHLSCVGDGKQELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYA
NELVEFIRSETGNHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGASSAITQYFFNADC
YFYFVERVRKLGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMESIQ
AFGEQVISEMCEELLTGGAPGLHFYTLNQAEPSLAIWDNLKLGR
>A3UED2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanicaulis sp. HTCC2633|TrEMBL
MDVSRGRRGASQGRMVMTVMGRSSSQGPKVSFEFFPPKSEEAEAKLWSSIERLYPLAPDF
VSVTYGAGGSTRDRTHRTVRRIVAETDMKPAAHLTCVSATCEEVDEVIRDYWDAGVRHIV
ALRGDPPEGLGERYQAYPGGYGNSADLTRGIKAIGDFEVSVGCYPEKHPDSADWDADLDM
LKAKIDAGATRAITQFFFDPDVYFRYLERVRKAGIDIPIVPGVMLQPNFKGLKRMAQMCG
AHIPDRIHAVYEGLDEDPDTRELVTAHLAAEMCETLNQGGADAFHFYTLNRAGLALSTCA
LLGVKSLQDVKAA
>A0A1B9ISG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kwoniella mangroviensis CBS 10435|TrEMBL
MPKITSLLEDRKGPFHTFEFFPPRTEAGLVNLLDRIQRLASAPLPSPLAVSVTWGAGGST
ADKSLELAEHITKLGLEVILHLTCTNMPKEKVDQALEKCKSLGIRNILALRGDAPRSEEY
STDPNPQPDYFQHADDLVRYIRKNYEDYFSIGVAGYPTPHPDSESFESDLEYLKVKCDAG
ADFIVTQLFYDVQGFLDWVQVCREKGITQPIIPGIMPIQNFSSFRRLVNLTKCPVPESIS
SDLLPISSDDSSVKKYGAELATKMVKQILESGLVPGIHFCTLNLEKSVRTILENLNWTAT
PTVKLEKSPLVRHNRLIEDDQPITNGAIAINGHSTSNHNNQISELSISPSEASQLAQWGL
QHHSLPPVPKKAAIQGAPSNSGQGQEDSWDEYPNGRFTDVRSPAYGEIDGWGSGLKITAA
QALKEWGTPTTLSELSEFFTSYLKSSPQTPTTPFCDLPLSPESLTILPYLLELNSAKMNC
WTVGSQPAVDAINSEDAIHGWGPRGGYVFQKSFVEFFVKPEEVRKLKEKVEKRGGGKISF
YAGNKKGDFKTNTEEDTVNAVTWGVFPGQEIVQSTIIETESFLAWKEEAFDIWTEWSLLY
PRHSPARKLLEGIASEWWLVSLIHHDYKDKEALWRFLLEE
>A0A5C4TI95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructilactobacillus sanfranciscensis|TrEMBL
MNLTNIFNEKTVFSLEVFPPHSAKETNNLIDSFKGVNSIKPDFISITSGAGGSQNDISLE
LAKQFQNDLGITTMPHITGLYRSKADVITFLNELGSNGIQNVLALRGDQIPDKKPVGDFK
RASELVKFIKKHGKFNIAGACYPQKHPESINFVDDILHLKEKVNQGVSYLITQTLFDNQA
FYDFRERLQFAQVDVPIEVGIMPCTNLNQIKKITELSGNPMPKKFVDIMDHFRNNQEAMR
DAGINYAIEQIVDLLSNNADGIHLYTMNNAENVQQIWNATHTLFAETSNHPTERV
>A0A1J4SAC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG1_02_45_11|TrEMBL
MKNNTSHLKKVLAKGNFAVTSECGPPKGADPQVILKKAELLRDVVDSINVTDNQTAIVRM
SSLAACSLLKTAGLDPVLQMVVRDRNRIALQSDILGASALGIRNVLCLSGDHQSFGNQPQ
TVGVFDLDSIQLVQAVKNMRDQGVIVGGAALDTPPEIFIGAAANPFADPLEFRVMRLAKK
IAAGAQFIQTQCIYNIERFAIWLNMARARGLTEKAYILGGVTPLKSPGMARYMKNKVAGM
DVPDELIKRMEGVPRDKQREEGIKICVEIINSLKEMSGVKGVHIMAIEWEDTVGEIVERA
GLLPRPAVDSE
>A0A7C3WN86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans|TrEMBL
MNLTAGSNLEKILKSGQKAVTCECGPPRGANADHFRHKAQYLKECADAVNVTDNQTAVVR
FCSMAACRILLDMGIEPVMQMVTRDMNRIALQSNILGAAALGIKNLLCLTGDHNSFGDHP
QSKNVHDLDSVQLLHCVKTMRDEGKMISGTEVDGRPAMFIGAAANPFADPFEFRVVRLAK
KIKAGAQFIQTQCIYDMDRFRKFMEMANDMGLTEKCYILAGITPFKSVGMANYMKKFVPG
IIVPDEYITRLKGVPKDKVADEGIKIAVEQIQQCLEMKGVAGIHLMAIEWEEKAPEIIKA
AGLLPRPKVS
>A0A7X2S438|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metabacillus mangrovi|TrEMBL
MGFLEDLQNEILIGDGAMGTLLYSHGIDRCFEELNLSRPDQVQSIHEAYIKAGARVIQTN
TYGGNFIKLSRYGLEDDIRRINSKAVKLARAAAGTDAYVLATVGGVRAFKKSSHTLEELK
RSFREQLFVLLNEEIDGLLLETFYDLEELKAVLDIARKETDLPITANVSLHETGVLQDGT
PLARGLRELEELGADVVGLNCRLGPYHMLESLDEVPLLDKAFLSVYPNGSLPSVDEGRLV
YESDEGYFAESALAFRDQGARLIGGCCGTTPKHIKAMADAVRGLEPIREKTVKAKKAAVS
VQERLEPAYPPLHEIVKERRSVIVELDPPKTLGLDKFFKGAEELKKTGIDSITLADNSLA
SPRISNVAVGTQLKERHDMRPLIHLTCRDRNLIGLQSHLMGLHSLGLTDVLAITGDPSKI
GDFPGATSVYDLSSFDLISLIKQFNEGLSYSGKALGGKTNFTVAGAFNPNVRHLNKAAER
LEKKIACGADYFISQPIYSVKQMEEVHDAVKHLSAPLYIGVMPLTSSRNAEFIHHEIPGI
KLSDQIRSKMAEAGSDPVRAKAEGIAIAKEIIDAAFDLFNGIYLITPFLKYEYSVELAEY
IRDKEQQRSEREFSHVQHS
>E2SNE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium 3_1_53|TrEMBL
MITEYIKKQGYFLFDGAFGTYYAQKYEDDQEPCELANLYHPQRVANIHREYIEAGADAVK
TNTFSANEQHLECSWDIIRRLLQEGYRIAKNAAQDQALVFADIGPIMEQKNVSLFTQYKR
IIDVFLEEGADCFLFETLLNTHALHEVSAYIKKRCPNATIVVSFAVTADGYSRQGIAMSK
LLQDCFADDDVDACGLNCVCGPMHMKRLLDTIDKTKKPILIMPNAGYPTILANRTYFRDS
STYFAKEMKQILEKGAALLGGCCGTTPVYIRKLKDALQERKEQMEAVIQSVPAQKKVNRR
DCNPLRRKLQKKQPVIAVEFDPPANCEIERFLNNAEFLKEAGVDAITIADCPIARARVDS
SLLACKLHRELDLEVIPHMTCRDRNINATKALLFGLQIEGIRNVLVVTGDPIPSEDRQEV
KGVFNFNSQILAGYIRDLNKTMFSEPFMIFAALNLNAVNFEAELMKAKRKVEQGVEGFLT
QPIHSHQALANLRRANAELDAYLLGGVLPIVSHRNAVYMNNEISGIEVDEEIVSLYEGTT
REEAQRLAVTISCQSVDEMRPYVDGYYLITPFNRVEIIADIVAHLHRQEEDASKKQ
>A0A847JDL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacteriaceae bacterium|TrEMBL
MTDRRKASISFEFFPPKTEKMEAALWASIEQLAPLAPDFVSVTYGAGGSTRERTHDTVAR
LVRETKLKPAAHLTCVSATREEVDQVIRSYAEVGVTHIVALRGDPPEGVGAAYRPHPGGY
AYASDLVAGIRDIGGFEISVGAYPERHPESADWDVEIDNLKRKVDAGASRAITQFFFDDD
LFEAFLDRVRAAGIGIPIVPGIIPIHNFTAVAGFAAKTGASVPKAVAERFARVEDTAEAR
ARAA
>A0A1V6A677|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium ADurb.Bin157|TrEMBL
MQNFMNYIENDVVIFDGAMGTRLYEKGVYINRVYDELNLSQSALIKEVHQEYLDAGAMVL
ETNTFGANRFKLEPHGLAEKLEVINFQAAKLAREVAGDKAWVAGAIGPLGIRIEPWGKTS
VQEAEDAFYEQAKGLLAGGVDLFILETFFDLNEMHQAIKAVRRLTDKPIIASMTINEDGN
ALYGTSVDVFTAKLDEWGADVIGLNCSVGPKTMFDAIEKMHGITSKPLIAQPNAGLPKVV
DGRMIYLCNPEYFGEYARRFIQLGVRAVGGCCGTTPEHIKWVANAVRSLTPGGKKAISQI
LKSDVKTESEVTLISQKDKSAFGEKLAAKKFIVTAELTPPKGCDADSVIVKAQQLKDIGI
DAINIPDGPRASARLSPLALALLIEKKVGIETILHYCCRDRNILGIQSDLLGAYALGLRN
ILAITGDPPKVGNYPQATAVFDIDSIGLVNIVNRLNHGRDLGNNPIGRPTGFVCGVGANP
GAIDQDLEVRRFEWKVDAGAEYAITQPVFDVDLLERFLEKIKHVRIPIFAGIWPLTGLKN
AEFMNNEVPGAAVPEEIMERLRKANSIEAQREEGIMIAREALERVKKLVDGVQLSVPFGR
VENIVKIIDVLGL
>A0A6P8IXC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinia tenebrosa|TrEMBL
MGLGQQEPATPTIEIIQDLENQSKSSSPISVPSTPLSLIEKIKNKIAMDEKFFSLEFFPP
RTPNGAVNLLGKFDRAARGCPMFCDITWHPAGDPSGDKETSSMTVASAALNYCGLETMLH
MTCANTTKDDVTKHLQKAKGLGIRNILALRGDPPDGDEWKALDDGLAYGTDMVRHIRKEF
GDNFTICVAGYPAGHPDCNNYQEDIQHLKEKVDAGADFIITQLFFENKTFFKFVKDCREV
GITVPIIPGILPIQGYASLRHLVKLSRLEIPQSIIDALQPIKDDDEAIRKLGIQMALDMC
RELLDSGIVPGLHFYTLNREIATREILCALGLWCSDPAASRPLPWRASANQKRFTEDVRP
IFWASRPKSYLYRTSEWDEFPNGRWGNSSAPSFRDLSDHHFFYLRSRAKIDERLKMWGTK
LERVEDVYEAFSCYISGKENREGVKVKSLPWNDDELASETDIIKAKLEYLNSEGILTINS
QPAVNAKPSTDRLVGWGGEGGYVYQKAYLEFFTSPETVSILLEVLKDYPLVNYHVVNAEG
TVDITNCHQDTPVAVTWGVFPGKEIMQPTVVDPISFKIWKAVGSPTVYRGPG
>A0A5F1ULC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPGELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A318SFP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus yavapaiensis KR-236|TrEMBL
MTVKFADKLGRSFVVTAELDPPRGPDPTPTISEATALVGLVDGVNVSDSPMANLRMNSTV
TASIVQRETGLTTIAHLTCRDRNVLALQADLLGAHALGVRFVLCLRGDPPTRGDHPDATG
VFELGADGLASLARGLNEGRSLTGRDLGGHTDFGVGVALNPTNPDLQAEAVRLREKLDAG
ATFAQTQPVFSRDDVERFLDVIGTPPLPILFGVLPIRSAKMAQNVSKWAKVPTELLTRVE
ERGKAAGIEWSARLVEDLRDLGVAGVHLYPLGKPDVAREVLGATLPV
>A0A1E4JCT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. SCN 67-18|TrEMBL
MTRSLHQQPDARRAPDASLFADLSGDCAVSFEFFPPKTEKMEATLWDSIQTLSPLGPRFV
SVTYGAGGSTRERTHATVSRIARETPIAAAAHLTCVDASRDEIAQIAHEYWAAGVRHIVA
LRGDPPEEGMRFAAREDGYASAADLVAGLKRLHPFEISVAAYPETHPEALSAASDIDNLK
RKLDAGANRAITQFFFSPDAFFRFRDAAAAAGVDAEIVPGILPVSNVAQTRRIAGLCGTS
IPPWMDRLFEGLDDRPAARQLVAATIAAEMCQKLYTGGVRHFHFYTLNRAELSYAICHLL
GLRPNASEGERAA
>F4CV10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 / CB1190)|TrEMBL
MGVSTPTALSPEIPGRLADALRSGRFAVTAEVAPPRGADLGPVRRAADHLRGWVDAVNVT
DNAGANVRVSSLAGSLALLEAGVEPVMQMTCRDRNRIALQSDLLAASALGVPNLVLMTGD
RPEQGDHPDAAAVFDLDSGGLMAAARSLRDEGVLLSGRSVDPAPRWLLGAVDSPGPSADR
FAQKVDGGAQFVQTQFVFDVDAFSGWLSQVRDRGLDARCGVLAGVGPIRSLRALEFLSSI
PGVSVPEQLERRLRGVPSDKVAAEGVAACVDTVRELRELPGVAGVHVMVVGDERGVPEIL
EAAGMARTS
>A0A316A9W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Quadrisphaera granulorum|TrEMBL
MSTPVTSAPLLARAPDCPKSMTYGPCGGVNPDDTCEVAPTTCVFLRRSLPVPWTPSAAGG
GKDVATRAGRELQAIARRRPLVLTGIPARAMSSQTVAPTAAELAGSVDAVLSGDAGRARV
QFPPSYRAALIAATGLRVWMGVTSRDRNRTATDAELASLAALGAAGVHCVTGDHTRTGDR
PDARPVFDLESTTMLPRARALGLFASFAESPAAPDVASRGARVAQKQRAGGQLCFTQYAG
DVDDELAFVARCRDAGATVPVLPGVPLVVDREGAELLASFHAAKLTTGFLDRLFAARDVR
AEGVRLAVAHGSALLDSGEVGGVVVAGGVRRGHEVAYATALATVARELGGGS
>A0A397T3T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glomus cerebriforme|TrEMBL
MKVINKILKAHEEGRPYWSFEYFPPKTQQGVQNLYDRMERMYRLGPEFIDVTWNAGGTSS
QLTSEIVATAQSVYGLETVMHLTCTNMPKEKIDKALKDAKECGCQNILALRGDPPRGQEH
WEACENGFSHAIDLVRYIRQQYGDYFGIAVAGYCEGHVDNPDKDDDLYRLKEKVDAGADF
IITQVFYDVDLFLKWVKKCRAIGISCPIIPGILPIQNYSGFNRIITLSKTIVPQFVLEEL
EPIKDDDAAVKEYGIKLATDMIRKMFADGIKGYHFYTMNLERSTRIILETLEFVPPVENV
KPLPWCPSLSAKRKKENVRPIFWRNRTKSYIARTEAWDEFPNGRWGDSRSPAFGELDGYG
VSLKHSKKEALALWGYPQKLSNIFDVFVQYCRGEVNSLPWSDLALAEESDIIREQLAHIN
SLGYLTINSQPAVNGVRSDHKIFGWGPKNGYVYQKAYLEIFISPTQLDALIARIESDSNI
TYYAVNKQGDLKTNTQSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELWNEWAK
IYDTDSISAKLITDIAENWYLINIVHNDFHDNDGIFKIFEQINVADYEADR
>A0A1G6YYZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas alcaliphila|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLPR
>A0A0Q6BZQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas sp. Leaf454|TrEMBL
MALRAPTSGKDIRVSFEFFPPKSEKMEETLWAAVERLAPLSPSFVSVTYGAGGSTRERTH
HTVSRILKETQLAPAAHLTCVDASRGEVDQVIRQYRDTGVRHFVALRGDSQAGAGAAYTA
HPDGYKNAVELVAGLRSIDDFEISVSAYPEKHPESADFATDIDLLKRKVDNGATRAITQF
FFDNDLYERYVERVRKAGIYVPIVPGIVPIHDFVKVARFSQATGATIPSWLAERFAGLEN
DAHTRSHVAAAVCAEQVLDLVERGIDDFHFYTMNRADLVYSICHILGLRPQAAGQAAVEA
SAAAAA
>A0A4R2TIA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. PP-CE-1A-559|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGISFEFFPPKSEKMDAQLWEAIRTLEPLAPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPSEKVAAA
>A0A316A988|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Quadrisphaera granulorum|TrEMBL
MPGLTCSFAAAADHLRDLGFAPELVSAPASARESGDALATIPRGAAATSFAEAVTTGGVI
TAGLPVRSRDPGLIAEAGSRLSAMSAVVTSEGLGTTLSPSHTALLLAGTGATVLSALTCR
DRNRVALEGELAALADIGVAGVLAVTGDHSSSAGLPGTSRIGTTTATMTEPVFDLDSPRL
AALARRAGLFVAVVERPAAPPSSCRPSRLALKASAGAELVIVDLNGDLADLATFTDALAA
TGAALPVLVSVPVVTTDAAAVHVATAWAQLVLSAPGVSGVHLSALVDDTDPTGLGTQGLG
AVDVLVRMATQLREHLERVPPPPRVEPAA
>F4CJ90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 / CB1190)|TrEMBL
MTLRGAFEAGRFAVTAEIGPPRGADAEAITRKADLLRGWVDAANVTDNQGAHVRMSSFAG
SLLAMRAGVEPVMQLTCRDRNRIALQSDLLAAGALGIPNVLLLTGDHPRFGDHPDAAPVF
DLDSTQLVWAARSLRDGGTLASGREIGARPDWLVGAVENPFAPPRRFRARRLAKKVAAGA
EFVQTQYVFDVDVFTTWLAELRDLGVTERCRVLAGVGPIRSLRVLEFLRHGVPGIHVPDQ
VVRRLRGVPADRVAAEGVTMCVETIQQLAELPGVAGVHLMAFGYERGVPEILERAGIAPR
PAPRPAPRPALTGSAPGAVTTEGLGHAG
>A0A327KSC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoplanes elegans|TrEMBL
MDARVEPAHDANESPVRLRQISSADRFGRPEGQAMAQTSTALRHSDHDVTDDTIASIAAV
MARATFETTRLAAADAAALAAHVRPGTLVYVSALPTKPFAEQRGVVEAVRAAGYEPVPHL
AVRSFASAAALSDHLAAMVERAGVTRVLVIAGDRSEPAGPFRAAIELIESGLLQGHGIHE
IGVAGYPDGHPRVAPVTLDLALAAKLTAAAETGLSAHVVTQFTMTPEPIVAWLTRLRAQG
IDHPVRIGFAGPASVTALLRYARICGVRASAQAFARNVGLVRDMLGTATPDRAVRGVAGP
GDRLGDVSPHFYAFGGLAAAVRWSAAVAAGRIALDRAGGFSVTPP
>A0A434M9Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M5C.F.Ca.IN.020.29.1.1|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRNYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAHDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A7D5W093|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQVARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQATPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALETRIEHWQSQVQSLEQWAPA
WHASWQMPGLPAVTFHPPQAGWRLDESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPLWATRAGAHVLHTLERSVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A832BS71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanomethylicus sp|TrEMBL
MRKAYSGFMRALSEGKFVFTGEVEPKKTTKLETIIWAANVLKSHVVACNVTDNPRARAYL
SSLVASYVIQKEVGLETICHMTVRDRNRLALMSDLLGASALGIRNVLVISGDHTTSGDNP
GAMPVYDLDSTQFVQMVRGMVDNGIDLNGNPIDGEVRLHVGVVGNPNADPLEVEICKVER
KINAGAEFIQTQIVFDVEMAKRFLKDLNSSIPVLIGIFPCKSYRVAEFIANKIPAISVPK
EYVDGLRGVECLSNASESKNKIDAVNVDYFSNFIKELKKTTKVAGIHIMTMGYESIVGKI
ADGLRNETRKGN
>X4ZZS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sabinae T27|TrEMBL
MKPDLRSAWASKVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVVDEVHRSYIEAGAEV
LESNTYSANYDKLSKFGLESKVEEINRAGIRIARQATGSAGYVVGAVGSIRAGKRANLSA
SELKKYFSQQIGAMLEENADGIMLETFYDLEELHLALRTARKLSDVPVICQFAVDETAMT
MDGLTLPEAFRILEDDGADVIGFNCRTGPIGIKRALGTLQGRLNLPVSVYPNAGLADYVD
GHYKYGASPEYFGQMARDFAGMGSRIIGGCCGTTPQHIAEIAAALKGYEPLPLTAPEPKE
KINVRIHESLVDDFEAEGGEPSLIDIVKERHAVIVELDPPRDLDISKFMAGAEALRRAGA
DALTLADNSLAVCRMSNMALGALVRQKTGLRPLVHIACRDRNLIGTQSHLMGLDALDIDH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKANFVIGAAFNP
NVKHLGKAVERLEKKIAFGADYIMTQPVYDPELIHKIADATAHLNIPVFIGIMPLASGRN
AEYLHNEVPGIQLSGEVRERMKGLEGEAGRAEGVAIAKELLDAATERFNGIYLMTPFMFY
DMSVQLLNHVWAKSGRQLSPLFR
>A0A0P7D1Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DGDKHQEAMHWMRRQATPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAEIVQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQARIHTLDQWAPA
WRASWQMPGLPAVTFHPPQAGWRQGESRVDASLKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQRLWSTPVGAQVLHKVERAVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAAQTP
RRLSPQPTPRSQPES
>A0A6J4X8Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius sp. associated proteobacterium Delta 1|TrEMBL
MKLKEALQKKKFVVTSEVQAPVDQEPEDLVRSLSQVRGRVDGVSLSEVEFEGIVGDTIKT
CELLNTNQLEPIYQTTTRDKNRLQLQKDLVDAHSAGIDNLLVFTEDYRITGDSLQEMMFF
HVDAGKLQSVLEHIRQGQTVEGDTLDSKADFLVGSGVESSWGKNVPDLEMKEMEEMTKLG
TGYFLTTPIFDVDQFAKFLKQAETFNVPVIAEVMILRTAGMARFLNRHIKSGMVPEWIIQ
KLTRAPNRQKASIEIFNDIVTGLKDLCQGVHIITIGAEENLKLYLDAAKLK
>A0A8C5ZVQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmota marmota marmota|TrEMBL
VKHKARVLPARLRCRSLEMWASEAGSMRWSVPPSISRRRAMETRGLGGPTPPSEGSSSGS
ESSRDGSRCSTPGLDPERHERLREKMRRRMESGDKWFSLEFFPPRTAEGAANLIARFDQM
AAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRREEITGHLH
KAKQLGLKNILALRGDPIGDQWETEEGGFSYAADLVKHIRSEFGDYFDICVAGYPKGHPD
AESFEDDLKHLKEKFSAGADFIITQLFFEADTFFHFVKACAATGITCPILPGIFPIQGYS
SLRQLMKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCRELLASGLVPGLHFYTL
NREVATTEVLKRLGLWTEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQDWDE
FPNGRWGNSSSPAFGELRDYYLFYLKSKSPREELLKMWGEELCSEESVFEVFAHYLSGEP
NRHGHKVTCLPWNDEPLAAETSLMREELLRVNQRGVLTINSQPNINGRPSSDPVVGWGPS
GGYVFQKAYLEFFTSRETVEALLQVLKKYELRVHYHIVDVKGENVTNAPELRPNAVTWGI
FPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYDEESPSRMIIQYIHDNYFLVNLVD
NEFPLDNCLWQVVEDTFELLNRPAQSERESEAL
>A0A1H7XUQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olivibacter domesticus|TrEMBL
MKITNHISNAKGKTLFSFELLPPIKGQSIQGIFNTIDPLMEFNPPFIDVTYLREDYIYKQ
HPTGLLEKVAYRKRPSTVATCAAIMNRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARKSDSSFIPTPGGHAFASDLLGHVVNMNNGKYLHDHMDDMEKTDFCIGVAGY
PEKHFESPNLETDFRYLKHKVDMGANFIVTQMFFDNTKYKAFVNKCRENDINVPIIPGLK
PITTSKQLISLPKIFHLDIPVALSEAIHACKNEKDVKEVGIEWMINQCKELIGMGAPVLH
FYTMGNPEPTKRIIRGVF
>A0A4U7BFD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. MIT 12-5580|TrEMBL
MNAKASFSFEIFPPRKSDSIDKIYTTLEQLKDLKPDFISVTFGAGGSINSQNTLDIASLV
QDRYKTSSIVHLPCIHQNKAQISSILNECKKRGLQKILALRGDIVEGKEKSVDFAYASDL
VRFIKEQGDFEIYAACYPEKHNEALNFTEDIHHLKEKVDAGANTLLTQLFFDNEDFYRFK
EYCDIANIKAEIKAGIMPIANKRQVLKITSMCGSKIPPKFAKILHKYEHNDKAMIDAGIA
YAIDQIVDLLTNGVSGIHLYTMNNAYVAKKVFEATHSLFEA
>A0A2A2YKN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SA15|TrEMBL
MALGTASTRTDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPQGLAYAVELVELIKNSGDFCVGVAAFPAMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVAAAGCETPIIPEVMPIASVKTLARVPSLTNAAF
PPALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHRPQA
>R7WVG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus rhodnii LMG 5362|TrEMBL
MLDDVIFDTVRGRASAGWRTTTPSIVDRLRGGDDTRIPFSVEFSPPRDEAAEQRLWRAVR
VFERLGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVDHSIDELRSMVGAY
ADRGISNILVLRGDPPGDPLGEWRRHPEGVEYAHELVRLVRDLGDFHVGVASFPEGHHRS
PDLDHDTRYLTAKLRAGAEYSITQVFFDVEDYLRLRDRVAAFDPEQGAKPIVPEIMPITS
LRSVRRMMELSGSRLPRHLEERLVRAAGSGPEEDRAAVRAEGIDIATEMCERLVDEGAPG
LHFITLNFARATGEVLERLGGRIRTAADSAPVRSVG
>A0A3N7F2N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. FJL06|TrEMBL
MNAANAQGTGFPVSFEFFPPKTPEGADKLRVARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVGAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFHY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLKAYVAKVEAGADSAITQYFYNSD
AYFRFVEDTQRLGAEVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A1H5MWC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinimicrobium catena|TrEMBL
MKITEHIKASKGRSLFSFEILPPLKGHNIQGIFDGIDPLMDFKPPFVDVTYHREEYVYIE
REKGLLEKRVVRKRPGTVGICAAIQNKYKVDAVPHILCGGFSKEDTENFLIDLDFLGIQN
VMALRGDAVKSELYFTPEADGHRYAGELVKQVAGMNEGKFLDEALENGHCTDFCIGVAGY
PEKHMEAPSLERDIQNLKAKQEAGAEYIVTQMFFDNERFFQFEQKCRENGITIPIIPGLK
PISIKRHLSLIPHRFHVDLPDELIREVEKCGSNKEVQEVGIEWCVQQSKELVAAGVPVLH
YYSMGKSKNIKRIAAQVF
>A0A1V1W0M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. PD653|TrEMBL
MRNKLSNALTLVRLLEQARYEVLPTATTEDKVLAHVPRDLAVTVTASPSKGLEATLDLAE
RLTGHGYAVVPHLAARMISGRAELAEICARLTGKGITRIFVPGGDADPAGDYRDALGLLE
DLADLGHPFSHVGITGYPESHPTIHDDLTVQAMWDKRHFATHVVSNLTFDPAVIRDWVHR
MRRRGITMPLLLGIPGPVDRTKLLSMATKIGVGESTRFLAKHKGTFARLAAPGGFTGERF
LEKCAPTLGEPTALVEGLHVFTFNQIAETEAWRTGLLDRLRR
>A0A2A2IW33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. HAR-UPW-AIA-41|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLNTYKDNGIRRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGEHFHIEVAAYPEVHPQARSFEDDLHNFVRKAKAGADSAITQYFFSADCYFY
FVERVQKLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDLESIQAFG
EQVVSAMCERLLDGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3M8B429|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus agri|TrEMBL
MTTSKKDLRDYLQDHLLVGDGAMATQLHALGAPVGVSFEELCLSNPRVVHEVHASYYQAG
ARLLETNTFSANRDALSRYGLEHKVARINRLAVAIAREAAQDDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGADALILETFLDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYSLTDAFPQLKKAGADIIGLNCRLGPAEILRSFEGTIFPDDSLLSAFPNAGRLG
MTDGEYAFKSSPEYFAESALRLRDQGVRLIGGCCGTTPAHVKAMADALASQQPKARVNPP
VALVERPHISVQSTHEREKPSIVERVKTGTTIIVEFDPPRDLDAEQFLDGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKNRHGIDPLLHIACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMAAAVARLEKKVEAGADYIMTQPVYDVESIRQVHEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSAEALERMKKVQGPAARQEGIAIAKELLDTAVRYFNGIYLITPFNYYE
MAAELIAYVRQQSALVKTAQP
>A0A2N2CPM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-16|TrEMBL
MVFLEKLKRGTVLFDGGMGTYYSEKYGRDPEFCEFANLSKPERIENIHREYIKAGADAIT
TNTFGANMEGLDCDWDTVAKIIESGWNVANKAVTGTDVTVFADIGPIPHIENVDNTAQYL
KIADCFLEIGAQNFIFETFSSLEGLSSVTEHIKTKNPNAVVICSFAVSPDGFTREGVSLA
RICQAMNTDEKVDVFGLNCSSGPNHMIKLLREINAPKKSIIAMPNAGYPTLVGSRVYFEN
NSDYFAQGLVDITDAGARIIGGCCGTTPEHISKTRRLLDKKDGTVRHIAAPKQTVEVEKA
ENRLWAKLESGKKIIAVELDPPANSDIRAFMDGARALRDAGADALTIADCPISRARADSS
MLACKLKRELDMDTIPHMTCRDRNIIATKALLLGLNIEGINNVLVVTGDPVPTAERGTIK
SVFNFNSVVLANYIHDLGEEFIRGPFRVFGALNLNALNFESQLRHAKEKLEHGVDAFLTQ
PVHSPRALENLKLARQELSGKILGGVMPIVSHRNACYMNSEIAGISVSDEIVKRYEGLDK
EQASRLAVSLTTEIAQNMAPYVDGYYMITPFMRTDLICEIMRNLK
>A0A8C4HCF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dicentrarchus labrax|TrEMBL
MLWSARDGSWQSSKSDSSGASNSGGESSKDSSRCSTPVLDADRSDRLRDKMRKRMESGDR
WFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVN
YCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAIDL
VKHIRSEFDDYFDICVAGYPTGHPEAESYEGDLRHLKDKVDAGADFVITQLFFRADTFLK
FLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRNYG
IQQAVDMCRLLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRK
VEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALL
QMWGEELINEESVYEVFTCYITAQPNSRGHKVMCLPWNDEPLAPETNLLKDELEKVNRRG
VLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNY
HIVDVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVADPVSFMYWKDEAFALWIEQWAKL
YEDESPSRMIIKYIRDNYFLVNLVDNDFPLENCLWQVIDDMFELLDASPEQLNDGTLSE
>A0A522V720|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedens sp|TrEMBL
MSFREKLLSGKFTVTAEISPPKGTDINGMMKEAGMIKDSVDAVCVTDNQRAIMRMSPIAA
CSALSQEGFETIMHLTCRDRNRLALQSELLGAAHLGIKNLLVMSGDYPTKGDHQGAKPVY
DLDSVQLLAMISSLNSGVDLSGNSLEGETEFFTGAVSNTELTEVALMKLGKKIKAGARFI
ITQAVFDAGRFSEFMDKIHDAVCKQTGIIAGIIPLRSEKSAHFLNKNIPGVKVPHDMIRR
IKATSEPEAVGIEIAADIIKELKGVCDGVHIMPIRTHEYTLNILEMAGI
>A0A3N0B3P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Slackia equolifaciens|TrEMBL
MYIADVFQAESLPVSFEIFPPKGELPLEEAREVVSGLAPLDPAFVSVTYSAGGGGNSGRT
IDVARMINDEFNLTSMAHLTCMNATRENIRQTLGAMKDAGIQNVLALRGDRVEGASAEDF
RFAKDLIPLVREAGFCVGAAAYPEGHVDCLDFEESIVHLKQKQDAGAEFFVSQLFFDNEA
ALRFLDHAHLAGIEVPITLGVMPFMSKSQITRMVFMCGASLPSPVVKLLARYEDDPKSLR
AAGIEYACKQMVGLAEAGADGVHVYTMNKPDVAAAAVEALGMAGFGPAAHDAREGAPC
>A0A3A9B3G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium 0.1xD8-82|TrEMBL
MKVTEIFEAKKKTGKPVLSFEIFPPKKEEALKNIDATLEKLCDLHPDFISVTFGAGGSTV
DNKTVEIAKKIKNTYGVEPIVHLTCLHYGKEEISGILKQLEEAGIENVLALRGDVNPNIP
VKYDFQYANELVEFIKTQGNFHISGACYPETHLEAKDAITDIHNLKRKVDAGVTHLVSQL
FFDNEAFYRFYEKTRIAGISTPVEAGIMPVTNKANIERMVNLCGASLPKKFERILKKYEN
NKEALLDAGMAYAINQIVDLIANDVDGVHIYTMNNSKVAGRICDGIRNLI
>A0A2N8MAW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beijerinckiaceae bacterium|TrEMBL
MNENPSCSFPRASRTVCPDISVSFEFFPPASAAMEATLWESIKRLAPLGPSFVSVTYGAG
GSTRERTHATVARIVNETHVKPAAHLTCVAAAGEEIDAIVRDYWDIGVRHIVALRGDPQD
GPGTKFCPHPNGYANSAALVAGIRRVADFEISVATYPEGHPESVSAGADIDVLKAKIDAG
ASRAITQFFFENEIYLRFLDKVQARGIDIPVVPGIVPVQSFQQTAKFAVRAGARVPQWLA
DRFEGLDDDPQTRKLVAATVAAEQVLDLVDHGVRDFHFYTMNRADLVYAICHLLGLRPKL
AQEAA
>A0A422HGZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecochloris sp. ZM_2|TrEMBL
MLVKEILSSAIEPVFSFEFFPPKKHEDWDRLFQTISELTPFNPSYVSVTYGAGGSTRSRT
HDLVTRIQKKTGLTVVSHLTCICSDKEEIREILSTYQEHGITNVLALRGDLPPGSTSYEE
ATKDFLHAIDLVRYIKDNFPDIGIGVAGFPEGHPETPNRLQEIRYLKEKVDAGADYIVTQ
LFFDNRDYFDFVERCTLEGINVPIIPGIMPVTTRKGLLRMSELALGARIPATLLRQVMEA
PDDRAVAGIGIEWATRQVRELIDHHIKGIHFYTLNHAEATGKIFHNISRTSIA
>A0A3S1RSN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.005.03.2.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQAPTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYIDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAEQSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>C5F201|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter pullorum MIT 98-5489|TrEMBL
MNKIENFIQILKSNEKCFTYEFSAPPSFSLDTFFDALQQENLVSKIHAFICTDSPLAKLK
HNSILASLKLQNTFNLPSITTISMRDRNTLAIQSELIGMNSLDLRLILALTGDPIRHGNQ
PQAKGVFEGNSLLLLKIIQQLNQAKDINNHPIQGDFKPFYAFSVLNSYSNKKENLYKKMQ
EKIQNGASAIITQPIYDLDIAQELLQWCDKINQESSTNCTLIFGFFPITSYKTALFLHNK
LPGVFIPQSWLETMEKASHNNTELEIGLEKSQRLFENLCKIQAKIHLMSSNKVDIIGKIL
NGR
>A0A7K9D3G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hemiprocne comata|TrEMBL
MVNETQHTCSASSTSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGVGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A839AFZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stappia albiluteola|TrEMBL
MHSPQSAHRADLDDGGNISVSFEFFPPKSEKMEASLWAAIERLQGLNPSFVSVTYGAGGS
TRERTHRTVARLLEETDLAPAAHLTCVGASKDEVDDIVRDYREMGVRHIVALRGDPLEGL
GAVYRPRADGYAYAADLVAGIRRVADFEVSVSAYPERHPESATWQAEIDNLKRKVDAGAT
RAITQYFFDNDVFEAFLERVRAAGIDIPVVPGILPITNFEQTMVFSAKCGTSIPHWLARR
FAGLEQDAETRKLIACAVAGEQVLDLVDRGVTDFHFYTMNRAELTFAICHMLGVRPAAAE
KQAA
>A0A085L9F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium SCADC1_2_3|TrEMBL
MSRLAKLLQQEEFVVTAEINPPKHACPESIKCQAEYISRYVDALNITDCSTAVVRLSSIA
AGFHVLSCGVELIIQMTCRDRNRIAMQSDLLGAYSLGMRNILCLSGDHQKFGNHPTAKNV
YDLDSIQFIYYLNRLQTEKIFFSGESIKENVPHFFIGAVINPFADPREFQVIRLEKKIRA
GAKFIQTQCIFDLEGFADFMEQVEWRGLHQKTHILAGVAPLKNYRVAQYMQNNVPGIVVP
DKVTNRMQRAVHPAREGIAICVEQIKRIREMKGIKGIHIMAMGWVEVIPEIVSRAGLYPR
PKIN
>A0A372GJ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. LHW52907|TrEMBL
MPRLRPARPPAVRELLASGAPSFSFEFFPPKTDKGARNLWRAIRELESLHPTFVSVTYGA
GGGTRDKTVDIVERIATDTTLTPVAHFTAVDHSQAELRNLVGRFAAVGVRNVLALRGDPP
GDPMGEWVKHPDGVEYASDLVRMIRSYGDFCVGVAAFPYKHPRSPDVESDTRFFIEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDVPILPGIMPVTQLSTIERSEQLSGAPFPPEV
KARFDAVADDPDAVRRLGIEHAAELCRELLEQDAPGIHFITFNKSTATREVYGLLDGAGY
GASGSVPPMTA
>B2IJ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIMB 8712)|TrEMBL
MSDTMTLQSIDSSPRASRGTCEGMSVSFEFFPPKTEAMEATLWESINRLAPLQPSFVSVT
YGAGGSTRERTHATVARIVKETPIKPAAHLTCVAASCAEVDAVAKAYWEAGVRHIVALRG
DPLEGIGTAFHPHPQGYAHSTDLVAGLRKIADFEISVSAYPEKHPESASIESDLDVLQAK
IDAGATRAITQFFFENDTYLRYLDKVRARGITIPILPGIVPVQNFKQTANFAKKAGASIP
PWLAERFEGLDDDPQTRRLIAATVAAEQVLDLVDRGVRDFHFYTMNRADLVYAICHLLGL
RPKLEKEAA
>Q48PB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGTPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1V3Q291|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. B05|TrEMBL
MASISFEFFPPKTDEQRAQLDRAAQTLKAHRPEYASVTFGAGGSTLSYTGDTVARLHSQH
GLNVAPHLSCMGGTRAELAALLDDYRAAGYRRIVALRGDMPSGMATAGDFRYAADLVRFI
RQHCGDHFHIEVAAYPETHPQADDALRDLHHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VHKLGVDVPIVPGIMPISNYSQLKRFSEMCGAEIPRWIAKRMQAHGDDAEAVRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRARATQSVLQQLS
>A0A5N6Z041|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus coremiiformis|TrEMBL
MHVKDKLAQNEAAGRIGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAADGGFRYAKDLVKYIREKYGNHFDVGVGGYPEGAEDNPDVDILIDHLKEKVDAGSSF
IVTQMFYDTDKFINWVKKCRAKGINVPIIPGIMPIQTYSAFIRRANWTKIHIPEDWLEAL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLEELKLMPSEETP
LQRPLPWRPSLGLNRRAEDVRPVFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSTRDLSHIFVRYLEGKLNRLPWSDTPISSEANSIKTKLIE
LNNRGLLTINSQPAVNGARSSHPVHGWGPKNGFVYQKAYLELLLPPYLLDELIARIESNE
DLTYHAVSKNGELRTNTRDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHDAASPSRKLIQGLMDEWYLVNIVNNDFHNTYNLFELFKDLDVRDLDVEVTAGNADSK
PQENGSAEATVRN
>A0A5R9AGR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nesterenkonia sphaerica|TrEMBL
MARRERAIPLGSAAHRASVRHLLERPRFEVIPLAGIVDEAANHLPAGATVTVTASPTRGP
EPTLETAAALARVGFHAVPHLAATQYCEESLPEALQQIGAAGIREVFIVGGDSAPPRAGA
GHDAGDRQDRFGDGLQLIEAVRRLAPQLHVGVPGYPEGHPRIPQQSLEQSLARKAEHAAC
VVGQLCFDPHTVTDWAVGLCARGLHMSVYAGLPGAVGSARLMRIAGRIGVGDSLRFLSSG
GTRTALRLVSPGRYDPTPLVTGLVRADGGVVVSGIHLYTFNALQETQLWRRRLLARLQEG
DPR
>A0A1R4KM90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteococcus japonicus LSP_Lj1|TrEMBL
MGSMPQDAPTIADLLAIAQRPLFGFEFLPPREEAEYARTLSAVERLEPLKPDFVSVTYGA
AGTNRERTVETTRQIAATSTIPVIGHLTCSSQSRQQLEGVIDAYAEVGVRHVLAIRGDMP
GGPTVPWEKHPEGLANATELVRLVKGRGDFCVGVAAFPDVHPERRDADLDARILVDKYEA
GAEFAITQLFFNPDAYFDLVQRVRMLGCPIPIIPGLQPVTSLKQVKFFEELSGAPVPEQV
KLRLGEADGDPARVREIGSRIASEIAVTLLRGGAPGLQFFTQNRSLATREIFAMLLERRW
>A0A8D5QWA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGVPPIHN
>A0A2H6GWW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon BMS3Abin16|TrEMBL
MVAANVTDNPLGIVIMNTLVPCHIMQNEVGLEAVYQVTCRDRNRIAIQSDILGAAALGIK
NVLALTGDHPSLGDHPQAKPVFDLGSVELVDLLRTMIHDGTDYAGNKLDVAPEMAIGVAL
SPGVEPLEPEIMKLEKKIAAGADFAQTQCVYDTGVLEKMLDATSHLDLPILPGIAPLKSV
GMAKFMAANVPGVTIPKEMIDTLKNAKDIKDATIEITAGLLHDIKELGFAGVHIMPVGMD
AYVGEIIDRAGIR
>A4IC95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania infantum|TrEMBL
MSKLISDAIAAEDVSKWYTSYELYPPRSEKAEEDMMKVLVPNFMRQSPVFLDLTWGAGGR
TSDTTMRLCKDLQHAYPDTPINMHITCTNTPKGLINEALDFAKTHGIRNILALRGDPPRG
EEFRADPDGFACARDLVRYIHDTYGDYFCVSVAGYPEGHPSRIAEDGAISDEDHQKELEY
LKEKVDAGASFIITQLFYDASLYVQFVKRCREIGITVPILAGLLPITTYAGFVRMVSLCK
TSVPSDVKKRVEELKENPDGLKEYGVEQCVQMIECIRTSGLDYHHLHFYTLNNSAQTFKV
LKRLNALVE
>A0A838D6S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRVDELFERAEEPVFSFEFFPPKSPEGEANLFRALEELSRMRPDFVSVTYGAGGSTRDKT
LEIVMRIREEFALEAMAHFTCVAATEVELRSTLDTLQRRGVENVLALRGDPPQGQEEWTK
TEGGLEYSRELVEMIDRDYDFSIGAACFPETHIHATDADSDLRYLKEKVDAGARFLITQL
FFDNAYYDDFVARARDIGIDVPIVAGIMPVTNVAQIQRFTAMCGSAIPDALTEQLEARRD
DPQAVTEFGVAYATLQCADLLAKGAPGVHFYTLNRSPATRAILSALRLMRPWERAGAPA
>A0A250WU83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlamydomonas eustigma|TrEMBL
MLYKHRFTPVTQLHTNTMFTVPAAKKLTHLPSTPCPESLILPLISAMRHLHAQSGPSSQL
TAFSEEHVEPSIASAAQHPELNVGQRQSHSSSIPQQSTSIKTPLRSRHFILSLERAVGLH
ALGSDEELRASGAFSAEVIPDLPIATTWGALARASASWFTAGSELKQQSNKKDGPSSHQP
VLAVSQLKAELSSVVTSRVNTVAVNLRSMAEVERRMIEASTSSASDQPHIKADSSSAALL
LVSGSHPLRTLPGVNRLLPSSVDALRAAKKLKSRGLIPGATQLWAVANPNLERDASLLEK
KVEHGATTILTQPPFDMAAFEAWLTDVERRGLPDHAVNILVGMPFISSPGNLAFWLSLAG
CSGRPACQQLLAGFQRAAAAAAGIAGKPQLHAYCAQYNADLLTQLCSRTGVAGFHVMPIT
ASSKKMAHQLLIREKVVAAVLPHGILSSSSSSAHATS
>A0A0H2KSL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulosimicrobium funkei|TrEMBL
MPDGGRARTHPGRSDVVSVADAVGQAHGGAARPTVSFELMPPRRPDAAPKFWETARRLVA
THPDFVSVTYGAAGTDRATARQVVGRLLQGTPVLPIAHLTCVGASREDVEEVISDFLDEG
VRSFLALRGDPPRDQPDWQPAPDGVRSSTELVALLREVEASRCASDPAAALRGAARPLTI
AVATFCDGNPAAGTTRAQEVRRLWQKQQAGASFAITQLFYDASSYTDFVAEARAAGVTIP
ILAGLLPTTEPARLRRVEELTGVRAPQHLLDALDALPDPEAQHAYGIAYTVDLAQRVLDA
GTPGLHVYTFNKHRAALDLLEGVHLGGGSAGTGGSTSAAAAPLVPDLASGPWVTGTSLPT
TSAATHGTPV
>A0A5N6AKD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces mimosae|TrEMBL
MALGNPSTMSGRAATVRDLLAAGKRSFSFEFSPPKTERGEKTLWNAIRRVEAVAPTFVSV
TYGAGGSSRERTVRATERIATETTLTPVAHLTAVQHSVAELRNIVGQYADAGIRNMLALR
GDPPGDPMAEWVRHPEGVSYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWETDIRYFVE
KCRAGADFAITQMFFYPEDYLRLRDRVSAAGCATPIIPEIMPITNARQIDRFQQLSNTSV
PPELKSRILAVKDDPMAVRSVGIEFATELCARLMDEDIPGLHFITLNTSSHSTATLDVYK
NLGLHQRS
>A0A2P5KS66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp|TrEMBL
MANVKERKSRLLGAGEIDVTFEFFPPKSEKMEEALWACVERLAPLRPEFVSVTYGAGGST
RERTHATVARIVKTTAMKPAAHLTCVNATRDEVDAVARAYWDAGVRHIVALRGDPSAGVG
SRYEPHPGGYANAAELVTGLKKIGNFEISVAGYPEKHPESPSVEADIDNLKAKIDAGADR
VITQFVFDTAHYLRYLERVRAAGIWVPVMPGIVPIHNFKQVAGFAGKTGATMPAWLARRF
EGLDDDAVTTQMVAVAVAHDQVMDLVDEGIKKFHFYTLNRADLVYAVCHLLGLRPVKSPA
RANAA
>A0A318I5V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella shahii DSM 15611 = JCM 12083|TrEMBL
MKVSDFLNKKVATKGLSFEVLPPLKGNGTAQLFRTIDKLREFNPNYINITTHNSEFVYRE
LDNGQYERDRIRRRPGTIAIAAAIQQRYGIPVIPHVICSGATVESIEYELLDLQFLGIQN
LLLLRGDKARDERMFTPTANGHAHTTDLIAQVNRFNEGFFADGTPMKHPGESFEYGVACY
PEKHEEAPNLDMDIDYLLQKQQLGATYAVTQLFYDNQKFFDFVEKARQKGVTIPIVPGIK
PFAKLSQLTIIPRTFHCDLPTALASEIVKCKTDDDARALGVEWATQQCRELYQHGVPGIH
FYTVSAVDSIYEVAKNIL
>A0A0R2SLS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium BACL2 MAG-120920-bin34|TrEMBL
MNSAPTFSVEFFPPKDQAGEERLWSALKALEVYKPDFVSVTYGAGGSTRDRTIRITSEIT
ARSGLSTIAHLTCVGSSRDELIEILSQYKVSGIKSILALRGDPKGGPGVKWESTAGGFDY
ADQLVLLASSMGFEVGVAAFPDGHPASKGNFEQDIKVLLEKERCGASFATTQFFFDVKGY
INLVNQIRAKGSKLDIYPGILPITNFAQLKKMSELAGSAIPIEIQRRVEAAGDSPEEVVK
VGIDIASELSKDLLDYGVPGLHFYTMNSAAPTIEIIRRIGLR
>A0A2S5M8V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp|TrEMBL
MAEPKERKSKLLGAGDIVVSFEFFPPKTEKMEDTLWSSITRLAPLRPEFVSVTYGAGGST
RERTHTTLTRLIRETELKPAAHLTCVNATKDEVNAVAKAYWDAGVRHIVALRGDPPEGPG
TKYAPHPGGYANAAELVTGLKRIGAFEVSVAGYPEKHPESASVDADIENLKAKVDAGADR
IITQFGFDNAHFLRYLERARAAGIWVPIMPGIVPIHNFKQVAGFAQRAGASVPSWLARRF
EGLDDDPTTTHLVAAAVATEQVMDLVDEGIKKFHFYSLNRADLVYAICHLLGLRPLRMPK
ADAA
>A0A2D5Z6V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaeraceae bacterium|TrEMBL
MLDASGFLIGVELVTTRGTMGQVTATRTRRLASDLVGCDRVDWVSITDNAGGNPMLSPEA
LGRPVLYGGKEVMIHLSCKDMNRHGLESQAWHLASEGFSNILALSGDYPAEGYHGRAKPV
FDIDSVGLLSLLDEMNRGLGKRPAVDANGEQIKGHRGGTDFFCGAVTTNFKLRENEVVPQ
LLKLEKKIACGARFVIAQIGYDSRKSHELLCYMQRRGHGDVPIFGNVFVLSRPAVRFFRR
GGIPGVVISDELHTECAAQGAAPDRGRRFFLELAARQIAIFRGLGYRGAYIGGVHDLGAI
EEILDIEASYSADDWKQFARAVRYPRPNEFFLYREKPETGLADPDTRHPAYQDALDNAGA
NHNVTLAYRLSRAMHSLVFTPGKPLYRLARRIYERSSNERRGPVALRVLEHAGKSVMFGC
KDCGDCSLPDIAYLCPESQCAKNQRNGPCGGTRDGRCEVHDYECIWARAYDRLKWEQRQD
HLLDHAPVIQDEALRGSSSWASLYLGRDHHGRNRPSPDDEATREDSS
>A0A6N6MI67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tamlana haliotis|TrEMBL
MKVTDHIKKANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVD
KGNGLLEKRITRMRPGTVGICASIMHKYKVDAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VVALRGDARKDESYFIPTKDGNAYASELVQQISNLNKGQYLHDDIKVEHNYDFCVGVAGY
PEKHMESPSLNTDLKRLKAKVDAGADYVVTQMFFDNQKYFDFVAKAREIGITIPIIPGIK
PLAVKRHLQILPQVFKIDLPETLIEAVESCKDNKAVRQVGIEFAIQQSKELKEAGVPFLH
YYSMGKSDNVQAIASALF
>A0A1T4PP51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenihalanaerobacter shriftii|TrEMBL
MGQNTLKESMLKKDEFTVTWELVPGRGAREENQEFIFDGAKQAAESDKIDGITITDNPGG
NPAISAEYLGMKAEEIGIPALVHFTCKDKNRNQMESFLYSLERENVNNILVMTGDYPVGG
YDGRSRPVYDMDPTQVLEMVTDLNSGLEYKDAFGRSVGLKDTDFFPGAAVSPFKKLESEQ
MVQYYKLKKKVEAGAKFIIPQLGYDARKFHELIQFIEMNNWDIPVIGNVYVLSYGASRAM
NANRIPGCVVTDKMVDKLAEEKEADDKGKHARLMRAAKMYAFMKGMGYAGVHLGGHGMGY
EDVEFIIDKGEELAPNWKDYIHEFDFPMEDGFYYFQKDSETGLNTDKPASKDYRPKNDLH
NRTFRVMHHAMFEPDGFLFKPMQLVCSAIDDSSLEKPFEFMERVIKTVSNDCQECGDCAL
FDLAYLCPMSQCPKNQRNGACGGSRDGYCEVYPNEKECIYVRAYDRLKPYGEEEQLKEYQ
IPPVNWDLHRTASWLNFYMGRDHSGKRMGITPPGSEKSGKSKKA
>A0A1Z9CXN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium TMED110|TrEMBL
MTSISLEFFPPKXAETEAKLWDVINELAVIRPDFVSITYGAGGSTRXRTHKCVKHLVTKT
DLKPAAHLTCVAASKSEVDEVIEDYAVAGVKHIVALXGDMPDMEAFSPHPDGYRGSVELV
DALSRRGGFDVTVSAYPEKHPESGDMQTDIDLLKAKIDAGATRAITQFVFDTEHHYRFRD
VLADNQINIPVIPGIMPTTNFKGVLRMSEACGASVPDWMKSKFEGLDDDLESRRALAIEV
ATEQCRDLIKSGFENLHFYTLNQATVTQAVCNALSLENVGVQ
>A0A074S3G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani 123E|TrEMBL
MKVTEKIQQAEKDGRIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSELVKTCQGAIGIETCMHLTCTNMHQEKVDIALREAKANGCRNILALRGDPPSGQEE
WTSVEGGFQHGIDLVRYIRREYGNYFDIAVAGFPQTIQLPEAEAKQEMQWLKEKCDAGAN
FIFTQMFYDADVFIRWVKAAREAGITIPIVPGINPIQTWNGFIRATSLSGTEIPQDLMDT
LEPHKNNDEKVRELGIKIVANLCRRILDAGIGIKGLHFYTMNLEKGTKMLLEELNLVPRV
ETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQTPEEGRKIWGTPTTIDDVKDLFAKFCSKEIKALPWSDQPPSTEMLVIGQQLT
RMNELGYLTINSQPAVNGVRSDDKAFGWGPKNGYVYQKAYLEFFVHPDQLQTLMKRIERD
TNVTYYAINKQGDLKTNSTSDGPTAVTWGVFPGKEVVQPTIVEAVSFMAWKDEAFELGCQ
WAKIYEPGSPSRKLIEDMMDEYFLVNLVHNDFHDREAIFRPFFADAGLKTNGCTEAPATN
GIKQVNGLTNGHAMTVHA
>A0A432EU48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquificaceae bacterium|TrEMBL
MTKQSFSFEFFPPKTDKGVENLKKVRHELAALQPDFFSVTYGAGGSTQDCTMSTVLETQQ
ETGVATASHLSCIGSSEAHIRQILSTYQENGIKRLVALRGDLPSGMQDIGDFKYANELIE
FIRKETGDYFQIEVAAYPEMHPQAPDFQTDIDNFVRKMNAGADRAITQFFYNADAYFYFM
DSLEKVGLDVPVLPGINPITNFVQLARFSDGTGAEIPRWLRKRLEGYGDDLESIQKLGLE
FVTDMCDKLMSQGVPGLHFYSMNRTEPSRTIWNNLGLSDLK
>A0A149V157|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter malorum|TrEMBL
MSLSRLSVELIPRSEDALAQDVTSVKTLFPAADTLNIPDLMRFPLRSWDAAALTMPQFDT
VVPHVRAIDIAPGAPLPGSTLPGLKEVLVVHGDPPADLAHRTYPNSTESIIRRYRKEAPH
LRIYAAFDPYRRAPWRELEDIARKKDAGAEGFFTQPVFDLKLFDLCREWLQDEQVFWGLS
PVIGPRSRSYWETTNHVVFPKDFEPTLDANIQFAQSVLRQLSQDQGCAYLMPLRVKLDQY
LPPLMSALTA
>A0A075SIP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis 6407|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A142FPF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. LQ44|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRAEIGELLDLYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEQMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEDVVTEMCEKLLKAGAPGLHFYTLNQAEPSLSIWKNLDISDREKIAF
>A0A2T2RDP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium SW_9_44_58|TrEMBL
MMSRFRQAVEAKEFLITAEVTPPKGGNPERMLQMAQSLKGRVHAVNITDGSRAVLRMSSL
AASVVLLRHEIEPVCQFACRDRNLIGMQADLMGAHALGIRNILALTGDPVKSGDHPKAKA
VFNLESVRLLKLIHKLNEGTDFNDKSLPDGELDLFPGAAVDPQLDSWSGLQKRFEQKIKA
GAQFFQSQMLTDFDRLETFMNEVAFQADKPILAGIFLFKSAKNARFIKNNVPGVHIPDEI
IDRLEKANDPLQEGKQIAAEQVKMARQLCHGVHMMAVKKEEVIPEILDLAGVKPVEDVKV
PEAARAH
>A5ERZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)|TrEMBL
MTDLATAITDGHAAIIRPKISFEFFPPKTEEMERTLWTSIERLAPLEPSFVSVTYGAGGS
TRERTHATIARILKETALLPAAHLTCVGASRHEIDEVVDRYHEVGVRHIVALRGDPPGGI
GTPYYTHAEGYQSSPELIAGIKKRHPDIEISVSAYPEKHPESRDFDADIDMLKAKVDAGA
TRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARGFVTRAGTTVPDWLAE
KFDGLDDDPETRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPKSA
NKAAA
>A0A2S7PM70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rutstroemia sp. NJR-2017a BVV2|TrEMBL
MLSDAQRAGTPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLAQLTCE
MVGVAQSQYGLETCMHLTCTDMGKDKIDEALRNAYKAGCTNILALRGDPPREKEKWVATE
EGFRYAKDLVRYIRQTYGNHFDIGVAGYPEGCDDQDDEELLLDHLKEKVDAGATFIVTQM
FYDVDNFIEWLGKVKAKGINAVIIPGIMPINTYASFLRRCNHMGCRIPPKWSAALEEVKN
DDAAVRNIGKDLVVEMCRQILNAGISHLHFYTMNLAQATRMVLEDLGLTPSSNRPLKQAL
PWRQSLGLGRRAEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDAYGIGL
KGTNEQNRKLWGEPASVRDIAEIFVRYLQNDIESLPWSEAPITSEADAIKADLIKLNYRG
FLTINSQPAVDGAKSSDPVYGWGPTNGYVYQKAYLELLVSPDVIEELINRIQRDPDLTFY
AVNKAGELRSNASGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDWAHCHS
SLSPSRQLIESVIGSWYLVNIVHNDFHKSHGLFPLFDGLTVENIDKPFESVAQDGEANGT
TNGAEAAPSQRSGTVWEKVRAGFNGIRLYIIAFNGLA
>D2TCL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia pyrifoliae (strain DSM 12163 / CIP 106111 / Ep16/96)|TrEMBL
MSFFHANQREALNQSLAEISGQINVSFEFFPPRTGEMEDILWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELRTIAEDYWNNGIRHIVALRGD
LPPGGGQPEMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMTSMFA
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAPALVL
AAS
>A0A178FAY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton violaceum|TrEMBL
MHIKDKLALAEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMPRERVDDALQSAFKAGCTNILALRGDPPREKEA
WEQTEGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFLDWVKKCRQAGIKVPIIPGIMPISTYAAFIRRTNWVKCAVPKGWMEAL
EPVKNDDAAVKQIGKALVSEMCRKLLENGINHLHFYTMNLAQSTTMVLEELNLKPSTETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSVRDLSDIFVRFLEHKLDRLPWSESAITQESEIIKDDLID
LNNRGFLTINSQPAINGAKSSHPIYGWGPRNGYVYQKAYLELLISPALIDEVVRRIESNA
DLTYHCINKDGELKTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSASRKLIQNTMDTWYLVNIVNNDFHKTHDIFDLFKGLVLKDIDTEVSGTQQATE
PAENGTHSEDPASKSEKQAVSAN
>E1ZJ72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorella variabilis|TrEMBL
MCSAAAAEATGSGLPGGSVPTGAAARRVAALFVRQPALCLERAVGEKHGIDQNLWDSCHF
QAEIYPDLPLATTWRDLLRRTVQTAGHESEVGRVEPPPKVCPAERWTVRTVAAQLRSRDQ
LRSMMLSAAGVDPAGDPKPGVRPADALLFVSGSHPARHLPGAGRWLQDSFDLLLLASAMR
EEGYLPASLSLWAVENPMLAPVKRLRQKADAGAEVVVTQPALLWDRVQRWADEADRELVS
HNVKVMLGLPIVPSIGNLDFWLRLCNVRGLPEAQALLQSFPQSEERDRKGHAAAVRQWNA
DLIRKSLSLPGVAGLHVMPLTKLARQMTLDFLADGTLPSRF
>A0A840NGJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora gloriosae|TrEMBL
MDTSTQRLQEMLCRSRFEVLPVRGAAERAAVLPAGSTVTVTASAAKGLDATMDVAARLAA
AGFHVVPHLAARSVPDRARLAELLDRAAALGSDEVFVIAGDSPVPAGEFPDALALLRAMA
ELDRKPGKVGITGYPERHAFLSDEVTIRAMADKARHADYVVSQICYDPRRIAEWLGEVRA
RGVLLPVHVGLPGAVDVTKLLRVSMKIGLGESLRFLRKQHGLVTKLLAPYTPDALLDGLW
PHLDEPAPGIAGWHLFTFNELDRTVQWRDDALARIQEVPA
>A0A7J8XCL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium aridum|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGIATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDLFLKFINDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGKFKYLTGL
>A0A061NPR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomicrobium sp. JCM 19038|TrEMBL
MSFLERLKETVLIGDGAMGTLLYSRDITGSIEQANLYAPELVYEAHLEYVQAGADIIQSN
TYAANRIKLDTYGLDLQVAKINKEGMKLAKKAAALKPNVYVAATVGGIKDGRTSDWTDDQ
IDETVTEQIVALLSENPDVVLLETYYDLYELIRAVRIVRNHHHSIPIIANVSLGDIGVLH
GGITLTEALKRLKKEGVNVVGVNCRMGPAQTITSLKETEIPEGLFLSAYPNASLPGIRDG
RLVYQSNPNYFKAQASSFRELGINIIGGCCGTTPEHIRGLKERLKGLAPLEKRTVVIEEA
TDEQVEANESNQQVYDANVIVELDPPKSLSKMPVFLKGAEALVNAGADSITLADNSLATS
RVDNVAAATLIQQKTQASPLVHIACRDRNLIGMQSHLLGLHTLGVKEVLAITGDPTKVGD
FPGASSVYDLTSFDLIAMLKGMNEGYSYSGRPLGVKTSFTVGAAFNPNVSNLEKAIKRLE
KKIAAGADFIMTQPMYDKEQIKRLKDYTKHLSIPIFIGVMPLVNERNAEFLHNEVPGISL
SDTVRSRMQKTHGDPQKGEEEGLRIAEELQQTCIELFGKVYIVTPFLKYHMSTALVEHAR
SLIKTSSVMT
>A0A834NGZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vespula pensylvanica|TrEMBL
MFVPDRDNLLASIRKPCEDIFSCTDALLELNDQYSPQIVLLCACAIFGALLISFIPGRIP
NRIPGSISARIPGLFPGPFPGLFPGFSGSIVIAKCAKLIMRSFVAGIKVTLEGKINNDND
CKITKDCRLNRRTNEMVDLQQVINEKVNKKEVFYSFELFPMKGSSDIYKRFFAEMDKYSP
LFYALTWHSKGLINSYLSLDIVEQFPSRTLLHLAAKGLKRCNVEMILKRAYNLGIRNIFA
LQGDSILEDGDFPHAIDLVKFIRSCFGKKFSICVAGYPDMHPLSPNKDFDLFYLKAKVDA
GADFIITQIFFESDTFINFVNDCKNIGITIPIIPGIFPIPEYKCLQRMTNICRLHIPRKI
VDRLETIKDDDEAVKNFGIEFAIDLIKDILESRASYGFHLFTLNKIPMAQNICNQLNLTY
QLHSEQL
>R4KG82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium pasteurianum BC1|TrEMBL
MKIKDMYNKEIPLISFEIFPPRKETNIESIYNTIDILSSLEPDFISVTYGAGGSNDNKTM
EIASIIKNKYNIEALAHLTCITSTKNDIENTLNNLKENNINNILALRGDFPSESYKQNKL
EYKYASDLINHIKTKQSFSIGAACYPEGHIECKSIRENLLHLKQKVSMGAEFLITQLFFD
NEYFYDFNEKIKEFNINIPISIGIMPVTNKNQLLKMISLCGANLPDKFIRILTKYEYNPE
ALKEAGIAYATEQIIDLLSYGADGIHIYTMNKPEIAKKILSNISYIRKTNKIS
>A0A657AJ51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleiphilus sp. HI0043|TrEMBL
MHSQKQFKHRFSFEFFPPKTEAGMEKLQVVRDELARRKPDFFSVTYGAGGSTQERTIDTV
LKLQDQGISTAPHLSCVGSTTENIASLLDHYIEHGVNRIVALRGDLPSGMGSAGELKYAN
ELVEFIRKHSGDHFNIEVAAYPEFHPQAPSAEADLLNFKKKVDAGANSAITQYFYNADSY
FYFIDRCEKMGINIPIVPGIMPITNYSSLVRFSDMCGAEIPRWIKKQLEAYGDDTVSIQK
FGEEVVSQMCEQLLKAGAPGLHFYTLNQAEPNLKVWDNLGLSDEEKIRF
>A0A5F2GYZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.220.01.1.1|TrEMBL
MNQFRFSRRPDIGEKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVIREFVDFGVTRFVALRGDPAAGVGT
IYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLGNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
AGSAAA
>A0A3S9Y8Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lydicus|TrEMBL
MALGTASTRTDRAHTVRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVRHPDGVGYAADLVQLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVA
KCRAGADFAITQMFFYPEDYFRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A1J4W167|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG1_02_49_10|TrEMBL
MSKLKDAFDAGRFAITSEIGPPKGTDIKEMLEDADLLKGKVEAINVTDLQSSVMRVGSLA
VCSLLKQRGHEPVFQMTCRDRNRLALQSDLLSASVLGIENVLALTGDHTSLGDHPDAKAV
FDLDSVQLLGVIRTLMEGRDMAGKDLKGKPDFYVGAVVNPGADPIEPEIIKMEKKVAQGA
KFFQTQAVYDLKKFEDFINKVKHLDVKIMVGIVLLKSAGMAKFMNKNVAGVFVPDEYIKE
MEEATDKKAKSIEIAARIIKGTKPLSSGVHIMPIGWDKLVPQVLEASGL
>A0A2Z3R3Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacter sp. SPIII_3|TrEMBL
MESQKRHARVFSFEFFPPKSEEARGAFHAALEQLAPLDPRFFSVTFGAGGSTRERTLETV
REIAGHGKAAAPHLSCIGATREGIRDILATYKALGVRHIVALRGDLPSGMVDPGDFRYAS
ELVRFIRAETGDHFHIEVAAYPEVHPQATSAEDDIKHFQEKIDAGANSAITQYFYNADAY
YWFVDTCEARGLTVPIVPGIMPITNHRQLVRFSEACGAEVPRWIRRRLEDFGEDGESIRS
FGLDVTTALCAELLAAGAPGLHFYTLNKAAPSSVIWERLGL
>A0A2R6NW46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hermanssonia centrifuga|TrEMBL
MEKGSIDVALKEAKDRGIRSLLCLRGDPTRGEETWLPTDARFQHGIDLVSYIRSQPEYTD
FDIGVAAYPDGHPESDVNEQDEIEYLKAKVDAGASYIVTQLFYDVDGFIRWEKKVRDKGI
TVPIIPGIMPIQTYASFLRLTKLCGTRVPPSLMEDLVPIRHDDQKVKDYGVKLAIKMIQR
LTTEAKVPGVHICTLNLEKSVQRVIEGLGWSGSSLKYTNKLIADVSGTATPTSHPELELV
ITPHNATDSATTQLAVGPATETEAGKGELNNAATWDDFPNGRFGDFKSPAYGVSNPWGTS
NITRNQALSQWGYPKTVDDISKVFLRYLHSKSISTPFSPEPLSPESLLIIRHLERLINKG
WWTVGSQPAIDGVNSSDEVVGWGPKGGYVYQKCFVEFFVENEDIDKIEKKVRERGQGWVD
YFAGNLEGECRTNVSEGGRNAVTWGVFPGQEVAQSTIIEKESFLAWKEEAFSTWAEWASY
YPPDSAERKILEDVRQRRWLVSIIHHDYKDPDALWTFLFNED
>V5SDD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium nitrativorans NL23|TrEMBL
MAFEQADLVRFPSRPERKSLFLERGDIDVSFEFFPPNSAVMEEALWRSIHRLEPLRPTSV
SVTYGAGGSTRERTHATIARLLRETTLHPAAHLTCIGATRAEIDRIAGMYWDLGVRHIVA
IRGDPPPGERYVPTPGGYERAVDLVEGLKAVADFEITVAAHPERHPDSTTLATDIEVLKA
KIDAGATRIITQFAFDTDRFLRFEERARSRGITAPIIPGILPIHNFQHVAAMASRVGVGV
PAWLVRRFEGLENDRGTQRLAAAAFAAEQVLGLVDRGVTEFHFYTLNRADLVYGICHMLG
LRPQRNDVEYRDLVDN
>E6XHY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella putrefaciens (strain 200)|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAVDLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPNWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A2V9SZE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MAGDLLARLKKSPVLCDGATGTLLYAKGIFINRCYDELNVSQPDLIRGLHHEYLQAGAEI
IETNTFGGNSFRLARHSMENRVREINLAGARLGREAAKSFDVWVAGSVGPLGIRIEPLGK
TSYEEARAAFREQIAALVEGGVDLLILETFGYLEELHQAILAAREVNPKIPLVAQVTIDE
DGNCLDGSTPETFTPRLEEWGVDVIGCNCSVGPVAMLEAIERVRAVTSLPLAAQPNAGIP
RSVEGRNIYLCSPEYMASYARKFVAAGVRMVGGCCGSTPEHIRVMKSALRASEARSKVVA
PSASGGVATPLPSPALPVEKRSQLGAKLAAGEFLTMVEIVPPKGTDIRKELEGARFQALS
LLVQQQIGIEAVLHYTCRDRNVLCIQSDLLGAAATGIRNLICITGDPPKMGNYPDATAVF
DVDAIGLVNIVQNLNRGLDIGGNPIGVGTSFVIGVGANPGVPNLDEEIRRFEYKVEAGAE
YAVTQPVFDLSLLETFLRQIEHCRIPVVAGIWPLVSVRNAEFMKNELRVSVPNSILERMA
KAKTPEAAREEGIAIAREMLVAVRHMVQGAQISAPMGRYASAVDVLEALGSSRPATA
>A0A2V8YQU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MLSPEVARGLTPNIHLTCVGRDGTAAWRTLEDLHALGIENVLALTGDYPKAAGLQPPEAL
FDLDSVQLVRLIDEARQRGMPFWISVAVSPFKYTEADCAYQYLKVQKKIAAGADCVITQL
GYDMRKFRELKRYMDEKAIHRPVLGNVYVLSGKAAEKMSKGEPPGCWVSPELLEKIRTEI
KESDNGRAARLERAARMVAVLRGLGYAGAYLGGDHQADHVRWIIRRSEALDPRWQELEEE
FNYAPKNGFYFFQGNFAPAKKRGPLPRLLDQMAKLFPVNQEGLLRNFLVRLFRIVDKRPW
LSHAVERFEFAVKSPLFGCQACGNCVLSYMEYVCPQTCPKNLRNGPCGGTNNGQCEVVDK
PCVWVAVYERAKSAGRIADLQTYVPPPRRDLKRTSSWVNYFLGRDSRPGNILSTIVPLAA
LLPHEDLSRGASGYAPKPLSEANSKVPAVKINANRE
>A0A2V8KLP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MQDLLSRLEDHVLVCDGAMGTMLYSKGVFISRCFDELNISNPQLVREVHFDYINAGADII
ETNTFGANRTKLMTHGLAEHIREINSQGARIARDIAGDKVWVAGAIGPLGIRIEPWGKTA
IEEARAIFREQAQALADGDVDVFILETFFDLNEVYAAIRGVRDITDRPLIVQMSIEEDGN
SPEGTPPEVFAKRLEEWGADVLGLNCSVGPQVMLDAIERIAGVTARKLSVQPNAGKPRNV
EGRNIYLGSPEYMASYAKKFVQYGVRIVGGCCGTTPQHIKAIRAAVKSAGSVVLGPSLGT
PSARRLPPEGQGAASIPLESKSRLGGKIARREFIKIVEMIPPLGHDFAEAIEKAKYLQAQ
DVDAINVPDAPPSSARMSAISLAVLLEKSTEIESLAHYTCRDKNLLGMQSDLLGAYALGL
RNLLLLTGDPHQIGEHSDATAIYEVDSIGLTNMVNRLNHGVDVGGKSIGKPTGFVIGVGA
NPGAMNDLESKRFFYKVDAGAEFVLTQPVFDAAVLERFLDRSGNSKIPVIAAIVPLPNYK
TAEFLNYEIPGCSIPDAILNRMREAQSKSPDYARNEGIFIAREILERIHGMVQGVQIRGP
FDRYETPVEVLSVILKGATP
>A0A2V8KIQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MQRNPLREALQSRRFSHVVEIVASRISREARLLEVASQLATTPGVVAGSITSYAGGAPGQ
DPLRVGTAARARGLTPNIHVTCVSKDRQELRQYLETIAGLGLENVFALTGDYPRGATPVF
DLDSVQLITLMSELREQGMPLWIAAAVSPFKYTEPDCVYQYLKLEKKFAAGADYAITQLG
FDVRKFRELRQYLDERNLQKPVLGNVYVLGLKAAEGEPPGCWVAPELVETIQDEVKAKDK
GEAARLERAARMVAILRGLGYAGAYIGGTHNAQHVSWIIERGQILAPRWQVLLEEFTYAP
KSAFYMYEPRTDAHRKRLGFRDRAVNAFWHLLSPIQIPKGSVAEKWARAMFAWIDRRSSM
SHFLERAEFAIKSPAFGCQACGNCVLPDMQYVCPQMCPKQLRNGPCGGTNNGQCEVISEQ
SCIWVHVYERAKAADEIPLLKIYIPPPDRSLKGTSSWINYFLNRDSRPGRQGALPKAAKR
QQNLDQGVSPGLISQQNEPRTDGRCFKSAAPPGR
>A0A7V5CY78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MESASQSLILVIGKDAQLFELIRKATDERTKVDYVSAESEGLNQLRETRPQIIILTSSEP
AESVIGLSRKLREGWISRHSSLLVVEHNAANDTYRILSEENISMNLGPYLFQAGKAVAPV
SGEQFIPALGKVINAELKARENRFKNAILDPDGFCLVWEQIPGPGAFETRQEIVLENARK
AARSNRICAISVTDNPGGNPAIATDVLCAEIKRSGIEPLVHIAFRDRNRNQAESLLFQLA
ALDINNLLVLTGDYPSHLGFTGKAKPVFDLDSVNGLRLIAEMNRGLEREIMRKSTRLAPT
NFFAGVAFSPFKQMEAEVMGQYFKLKKKIEAGAHFVITQVGYDARKLHELLMWLKVFGYK
IPVLASIYVLSYPVARAMRANHIPGCVVTAKLLRQLASESASEDHGKQLRLERAAKMLAI
VKGMGYKGAYISGQALPFESLE
>A0A3E0P0E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKVVEHLDRASRPLISFEIIPPLRGGTLERLLELIDALQKFSPPFIDITSHSAEAYYEET
RSGIQKRVKRKRPGTLGVCALIQNKYRIDAVPHLLCNGFSREETEDFLIELRYLGIDNVL
AVRGDHSGYVKPLRDGRSANRYASDLVAQITAMNSGRYLEEDLLDADPSDFCIGVGGYPE
KHFEAPNLETDVQRTLEKVRAGADYIVTQMFFDNRHYFAFVDRCRAAGIEVPIIPGLKIL
TTKKHLTSLPSVFHLTIPPELSSAVEEAAPSEVRSIGVDWALKQTEELLDHGVPAVHFYV
MQSAVAIKELMNRLDL
>A0A4S2SFF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. A1547|TrEMBL
MSARPTPYPERPVPAPVTGGGLAELLRRVRYEVLPAKATEDKVLAHVPADVPVTVTASPA
KGLGPTLDLATRLAGHGYRVVPHVPARQVSDAAHLADIVDRLVAAGIEDVFVPAGDADPP
AGAYDAALPVLRRLGELGSPFAHVGITGYPESHPLIADDVTVQAMSDKQPHATYIVSNLC
FDPATLRQWLARVRRRHVVLPVHVGIAGPVERAKLLSMATKIGVGESAKFLTRHPSWFLR
FAAPGGYSPERLLRRSAPALGSPEAAVAGLHLFTFNQIAETERWRRAMLERIGG
>A0A2L0T506|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. XWY-1|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2D6R563|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MHRISDLHAARQAGDRPVISFEFFTPKTEAGDVKLMEVTMPALLELAPDYVSVTYGAGGT
TRTKTLTLVDAIQKQFDLTTMAHLTCVGHTRDEIAAILDEAKALGIRNILALRGDPPAGE
SEFSKPEGGFEFSYQLVDFIRKHGGDFCIGTAGFPEGHLACADGKLADWGYLKQKVDAGA
DFVLTQLFFDNADFFAFRDHMVNELGVTVPICPGILPILSSKQITRFTQLCGARMPMALQ
TRLEDLADDDAGATAFGIEYATRQCEELIREGVPGLHLYSLNKAHSVSAILGNLGLDHR
>A0A4Q3IZY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacteraceae bacterium|TrEMBL
METPNLSIEFFPPKTPEGAEKLRVARQKLAELNPKYFSVTFGAGGSTQQGTLATVLEIQA
EGHEGAPHLSCVGATRASIRAILQEFQAKNVRRLVALRGDLPSGYGGAGELRYASELVEF
IRLETGDWFHIEVAAYPEMHPQARSPQDDLQNFARKVQAGANAAITQYFYNPDAYFQFVD
NVHKLGVDVPIVAGIMPITNYTQLMRFSEMCGAEIPRWIRLKLASFGDDAASIKAFGLDV
VSSLCERLLVGGAPGLHLVSCVR
>A0A3N7C3W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. KBW07|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPQFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFLYASDLVAFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLRDGGAPALHFYTMNQSAATLALLERLD
>A0A2V9LL50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MGLASQTGASLLESLKKGEELFSAELRPPRAHSPGLQSMDDWIDTYHSIRRLNVAGFHVF
ITDNAVGRAEEENLRHLVTNLGPDARRSHIIPFLTSKHPLDYCLRYAERAYEQGFRTLVV
LGGDRHDGIPRCVEHAIQLRRIIRRSVPSLILGGWANPHADLSEQTDYLMRGREETDFFL
TQVVSHHDAEAVERFLELIGRRGIEIPGIFGVFYYRCARKSSLDTLRRFFPVPVREIEKE
FEVEELRADDVCARTIRKLRRLGVRRFYVSNLPVADAAARLQTITGLAAEGEGGG
>A0A523EYU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRDNTGDLEAVRRLFLKPEFEMLPFRSAIDQIEFLPEAATVTITASPAKGIEPTLDYATK
LAERGFDVIPHISARSIADETHLSRILDAIAEAEIDRIFVIGGDSKDAGEFPDGLSLIQA
IESLGYPLPEIGVAAYPDGHPFISRETLRQALKDKQPYASYMTTQICFDPVVISDWIADV
RSDGITLPIHLGMPGVVPVHKLISIAAQIGVGDSVRFLSRHRGLLGRLTRQSTYSPDRLA
MGLSQAIADPTADIEVVHFYTFNQVESSEAWRRGWLASIDG
>A0A6S7EKC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter dolens|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVAKVKAGANAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAELGDDKASIRAF
GVDVVTELCQNLLDNGAPGLHFYTLNHAEAPLAVWKELSV
>D5G9J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tuber melanosporum (strain Mel28)|TrEMBL
MDKVVNKIAALPPGEPYHSLEFFPPKTSMGFQNLQARLERMARALRPLFVNVTWGAGGST
ATKSLQLAEICQRQLGLTTVLHLTCTNTSQTVLDETLETAKEIGIRNILALRGDPPRSDD
YHNTPCDGTSNGAGKEFGYVIDLVRYIREKYGDYFCIGVAAYPEGHVEGASPEKQDPLFD
LSFLVEKVKAGADFIMTQLFYDADKYIWFEKLLREEPSGVLSELPVVPGLMPIQSYSMLK
RITKLSGASLPAYILRRLDDVKGDDEAVKRVGIDIVSEVIEKIKAANLSGPRGFHFYTLN
LEKAVSFIVERTNLIPPLHESVLEEIEGPDMNGAALRRDRRTSSVTSDPHNREGALGREA
TWDDYPNGRFGDARSPAFGEIDGYGPSLHLSQAQAIKLWSYPVTKQDVSDIFVQHIKGEL
EAIPWSEQGLSVESKVIADHLAKLNQKGFWTVASQPAINGVNSTDETFGWGPKGGFVFQK
AFVEFFCSTEDWEVLKARLERVEDVSYYAANKAGDYVASVPPGGSAMHAVTWGVFPGKEI
ITPTIIEEVSFKAWKEEAFSIWKEWARVYPPTSASSKLLMETAETYYLVNIIHHGYMDPE
FLWKLLET
>A0A6F8XER9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas meridiana|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAARNPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRDETGDHFDIAVAAYPESHPQAPSLDKDVENFARKMNAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GTDVVTRLCERLLDGGAPGLHFYTLNQATPVLKVVDNLS
>A0A444WW69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachis hypogaea|TrEMBL
MKVIEKIRAAAAADPDRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGS
TADLTLEIANKMQNMVCVETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQ
DKFVQIEGGFACARDLVKHIRAKYGDYFGITVAGYPEAHPDVIGSDGLATPEGYQNDLAY
LKSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCK
TKVSKSDIFAALEPIKDNEEAVKSYGIHLGTEMCKKILAHGIKTLHMYTLNMEKSALAIL
MNLGLIEETKINRSLPWRRPANVFRVREDVRPIFWANRPKSYISRTIGWDQYPHGRWGDS
RNPSYGALTDYQVLTITK
>A0A1M6R0Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter antarcticus|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQVVRDQLAGVNPDFFSVTFGAGGSTRDRTIETV
LSLHQQGISTAPHLSCVGGTREGISELLDLYKENGINRIVALRGDMPSGMGAAGEMRYAN
ELVAFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKLGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDKESIRK
FGEEVVTDMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISEREKIAF
>A0A2A5QDV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVSDTLRDLDAVGVHRILALRGDIIPGVEPLKDFKYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSGLLTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHEATHSLFKHHSQVSAL
>A0A2T3VZM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium punjabense|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLRDIAQDYWQSGIRHIVALRGD
LPPEGGKPEMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTSVFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPEATR
>A0A1T1BGE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus sp. LM3|TrEMBL
MTRVSVELVPRSRSGLRAEIAQVVAALPGVDTVNIPDLTRYSLRSWLGCAFARPAYRAVP
HLRAVDFNPREPLPFLGTLDQYGITEVLVVTGDAPADMSARVYDQDAVDLIRRLRREAPH
LTVYAGLDPYRQSFARERDYLERKLDAGAAGFFTQPFFDLRVMDAYSDLIPDGAQMWWGA
TSILTESSLNYWRARNHAVFPRSFAPTLECNRAFAADLLTFARERGQHAYFMPVKVDVQA
YLEGIL
>A0A653JG51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium 8X|TrEMBL
MPCGRPPAIKEKAVGLPISFEFFPPKTPEGVVKLRAVRQQLYRARPEFCSVTYGAGGSTH
TGTFATVGEILAEGVAAASHYSCIGATRETVRVQLGELKAMGVTRLVALRGDLPSGYGMG
GEFQYASDLIGFIRSETGDHFHIEAACYPEVHPQARSPEADLQALVAKVRAGANSSITQY
FFNADAYFRLVDEARRAGIEAPIVPGIMPITSSTQLMRFSDACGAEIPRWIRSRLLAYGD
DVASIRSFGLDVVTDLCRRLRDGGAPALHFYTMNQSQATLAVLDRLG
>A0A1Y5T8I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Palleronia marisminoris|TrEMBL
MCRVSYEFFPPKSLEASFRLRDTLNVLAPTAPDFVSVTYGAGGTTRQLTHEAVTTIAKTT
GLRVAAHLTCVDASKAQTLEIAESYAEAGITDIVALRGDMPGGAAFVPHGEGFCSSIELI
EALAETGKFTIRVGAYPDRHPEAPSDQADVDFLKRKIDAGATEAITQFFFEAETFLRFRD
RCAAAGIDAPIVPGILPIENWKGVRKFATATGTVIPAWLDQAFAVAARDDHTDLLATAIC
TEICSDLLSEGVDKLHFYTLNKPTLTRDVIHALGLAPEPGLEKVA
>Q2ILB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeromyxobacter dehalogenans (strain 2CP-C)|TrEMBL
MRITDLLRFARERGEPIFSFEFFPPKTDDGVRGLFETVEALRPLGPAYVSVTYGAGGSTR
AKTIDLVKRLKRDAEVEAMAHVTCVGASREEIAAVLDEVADAGIQNVLALRGDAPRGQSA
FVPHPDGFTHASELVAFIRSRPERWRFCVGAAAYPEGHVETRDLAQDLRNLKLKVEAGTD
FLVTQLFFENAHYFRFVERARAAGVEVPVVPGIMPFTNVEQVERFTAMCGAAIPPPLRAA
MEVRRADPDGARELGVAYATLQCADLLRRGAPGIHFYTLNRSPSTRAIVAALRASEPWRG
>A0A7W5F492|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces violarus|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSSDWDADVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVAAAGCDTPIIPEIMPIASVKSLARIPSLTNAVF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSPQA
>A0A6A6K5A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hevea brasiliensis|TrEMBL
MATTLALLSLVIQVLKAILGFLLCPILLHYPQKIISLCSSVIFRSEAHPDMIRSDGVATP
ENYQKDLENILFCAVGHACFLQVDAGADLIITQLFYDTDIFPEFVNDCRQIGINCPIVPG
IMPINNYKGFLRMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEVCKKILAHGIK
TLHLYTLNMEKSALAILMNLGLIDESKITRSLPWRRPTNVFRAKEDVHPIFWANRPKSYI
SRTLSWEQYPHGRWEDSCNPSYGALTDYQFMRARARDKKLHDEWATPLNSIEDILEKFKK
HCLGKLKSSPWSELDGLQPETKIINEQLGKINLKGFLTINSQPAVNGERSDSPSVGKLGG
PGGYVYQKAYLEFFCSTDKLQVLVDKCKSFPLITYMAVNKGGTLVSNVGTNDVNVVTWGV
FPAKQIIQPTVVDPASFNVWKDEAFEIWSRGWASLYPEDDPSRKIA
>A0A852PKE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus haemolyticus|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPQ
>A0A2K5VER6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macaca fascicularis|TrEMBL
MQPDTCASPLIAFAAPTEATLVRPAGERSESPGTEGRNLAMVNEARGNDSLNPCLEGSAS
SSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEITG
HLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPKG
HPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPIQ
GYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHF
YTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYLS
GEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLVN
LVDNDFPLDNCLWQVVEDALELLNRPTQNERETEAP
>A0A317KU99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gracilibacillus dipsosauri|TrEMBL
MTSSLLQALKENILIADGAIGTLLYAHGVDQCFEAYNLSKPEEVLQVHQSYIDAGADIIQ
TNTYGANYIKLARFGLEEEVHQINTRAVQLAKQAAKNETFVLGTIGGIRGIQKLVTSKKD
IIRSFKEQLFSLLLEGVDGILLETYYDIDELTAVLEIARKETDLPIITNVSMHEPGILEN
GMSLADVLTQLEVLGADVVGVNCRLGPHHMIESLEAVPLPERAHLSAFPNASLPAYENGK
LVYSKQTDYFKRCAKEFRDQGVRLIGGCCGTTPEHIRALKDGIEGLTPILDKTVQVKEGL
ITLPSSQTVQSNPTLVDKAKKQHTVIVELDAPKHLEIDEFIKGAKALEDAGVDAITLADN
SLATPRISNLAMAVKMKQLHLNVTPLIHLTCRDRNLIGLQAHLMGLHTLGFHEILAITGD
PTRIGGFPGASSVFDVTSFELTRLIKQCNQGLSFSGASLRENTAFQVAAAFNPNVANLEK
AVKRMHKKIEHGADYFLTQPIFSHEKIIALARETKHIEAPIFIGIMPLVSYKNAEFLHHE
VPGMKLSDEVRARMQARSNRADAIREGIEIAKELIDTAISYFNGIYLITPFMNYEITVEL
TDYVHEKTKAKSTAKVR
>R9V7C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida H8234|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFETDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A0B9A4V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium linens|TrEMBL
MVSLTATGLLDDFSLEMTGKDIPNLREAAHAIPQRTRINVTFLGNEDLPMRVEASKAVAD
MGFVPVPHISARRLKSERELRDFLDALQQVNATNHVFVVGGDPATPEGPYKDSLSVIRTG
ILQDYGVAEVGVGGYPEGHPDISDDDLWYHLDAKTSALAEQNLDQVVLTQFAFDAQRVSE
WVRDVRNHGIESVIRIGTPGPAGIKRLLGYARRFGVGTSAGIVKKYGFSLTNLVGTAGPD
KFVRDLSDRAEGLESPETLKTHFYTFGGLLATAEWAHKFADES
>A0A7U5BFX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas hengshuiensis|TrEMBL
MYAPPSLLDDASIEITAKDQHHLDQLARGFAPGTPVSITFLPGETFEDRIAAAQRVRAAG
FTPVPHISARRLTSVAELEGFVAGLVDAAAVTRVFVVGGDLPQPAGPFEDALAVIRSGIL
AFHGIEQVGIAGYPEGHPDIAPAALDAAMRDKLDAIHAAGQRAWIATQFSFDAVPVLDWL
ARLRAEGIDETVRIGVPGPASVKTLLRFATRCGVGVSAKVMTKYGLSLTQFLGNAGPDKL
IEALTAGLVPEVHGDARLHFYPFGGLEKTADWVARRG
>A0A373KSZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF37-3AC|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISSLKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>C9KNQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mitsuokella multacida DSM 20544|TrEMBL
MKRISVELVPRDEDALRGELALLGKFKEQVDVINIPDLLRFPTRSWQGAAIAKEYFPESM
PHIRAMDIDLDKELAMKDYLREHDIREVLVIEGDPPQDMMHEVYPTNSVDVIWKFRKEMP
EVKVYAGIDQYRGSLSQELYRIKRKLQAGAAGFFTQPFFDMRFLSVYADMLQGLEVYWGV
SPVMSARSQSYWERKNHVVFPHAFEPTLDWSVAFAKEVMDFAVREGNNVYLMPIKTNLEA
YLEGVLA
>A0A553GQ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carboxylicivirga sp. M1479|TrEMBL
MTVAELIKSSKQTGFSFELLPPLKGNSIDKVFKTIEQLKEFNPLYINITSHRDEMQYKDT
ANGLYERKVTRKRPGTVAVAASIQHSYGIKVVPHIICSGFTKSETEYALIDLNFLGIHDI
LVLRGDNSSKERFASAGQEGNAYAIDLVNQVNELNTGQFLDGTLLDAFDTPFSYGVAGYP
EKHEEAPNMDSDLFWLKQKVDAGAEYIVTQMFFDNAKYFDFVKRARAMGITIPIVPGLKP
ITLMNQLTVLPKIFHVDIPEDFAKEIRKCKNNDEVKQVGVEWCIHQAKELIQHNVPILHF
YTMMATNSTRKVAEAIY
>N9WJ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] innocuum 2959|TrEMBL
MNNAEFLKEAGVDAVTIADCPIARARVDSSLLACKLHRELALDIIPHMTCRDRNINATKA
LLFGLQIEGISNVLVVTGDPIPSEDRQEVKGVFNFNSQILAGYIRDLNETMFSNPFMVFG
ALNLNAVNFEAELAKAKRKAEQGMEGFLTQPVHSQQALINLKRARTALNAYLLGGVLPIV
SHRNAVYMNNEISGIEVDEEIVARYEGTSREEAQRLAVTISCQTIDAMRAYVDGYYLITP
FNRVEIIAELISHIHAH
>A0A5N7WBX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPEFCSVTYGAGGSTQAGTFTMVRDIQNE
GVGAASHFSCIGATHEKVRAELNELKAMGVKRIVALRGDLPSGYGLGGEFQYASDLVAFV
RQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VRALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A0C2ZKJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp. FS08-3|TrEMBL
MFETFLTKLQSDEKFITVEITPPHGASIGQIIENIDKLQLAHKIDGFSLTDNPLAKLKMS
GVLSAIKVQHYFQKPVIATMSMRDTNKLSMQSTLLGANDFDLRCILALTGDPAKLSDQPE
VKGVVERDSTLLLSIIYHLNKGVDYSNQSLNPPPKPIYPFAVSNSYSKDKTRLEKRILKK
LNYGARAILTQPIYDLDNAKELLEIFESAKNQSIRQSAKEAQLIMGQFPVVRARTANFIS
DKVPGIHVPKAIVDEMNLAAMDGEAKEQEVGFALSKAIFDNIMKLHGKVHLMTHNRFDLC
SDLIGKNFSIKT
>A0A2T1FH53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|filamentous cyanobacterium Phorm 6|TrEMBL
MNRFRTACTTPGEFIITAEVAPPKGGDITHTIAMAELLKNRVHAINITDGSRAVLRMCPL
AVSAILLQHGIEPICQVACRDRNQIGLQADLMGAHALGIHNILALTGDPVKAGDHPKAKS
VFDFESVRLLQVIQKMNGGSDWNDKPLTDGVTDLFVGAAVDPQSPSWSGLQSRFEKKVEA
GAQFFQSQLITDFEVFDKFMHHIAAGCNKPILAGIFLFKSAKNAEFIKKYVPGVHIPQET
IDRLAKSPAPLQEGIKIAAEQVKLARQLCQGVHLMAVKREDLIPQILDLAGIEPLS
>A0A387GXQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. CCGE532|TrEMBL
MSHIDENPLGVHLPLDPLPGHYSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGHAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLSSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFRDYMKKVRDLGLTEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDAVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRTDALVAERLHQISEGREENQQAMAEIAA
HHTPPQAH
>A0A0L8MWP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces virginiae|TrEMBL
MLAQGRRTFSFEFFPPKTDAGERTLWAAIRRIEALAPSFVSVTYGAGGSSRSRTVEVTKR
IAAETTLRPVAHLTAVGHSTAELRHIIGQYADAGIRDILALRGDPPGDPKGEWMRHADGL
THAHELVSLIRRLGDFTVGVAAFPERHPRSPSWTEDIRHFAAKCHAGADYAITQMFFHAE
DYLRLRDRLLAVGCLTPIIPEIMPATDFRQIRRFAELSDARFPDALAQRLEAAKDDPAAG
HRIGVDYATHMSERLLAEGAPGLHYITLNKSTATLEIHQNLNPSHDPATTITE
>A0A2Z5X4L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudanabaena sp. ABRG5-3|TrEMBL
MQTTFKIPLKFLFRMIDSPQPIVEHPFHKFRKAIASKEFLITAEVSPPKGSDPTHMLTQT
RSLKGRVHAVNITDSSRAVMSMSPVAASVLIQQQIGIETVCQLACRDRNRIALQGDLFGA
AALGITNILALTGDPVKAGDSPDARSVFDYESVRLLQLIQKLNQGIDANGKALPHQGTNF
LAGAAVDPQSRSWSGLQRRFERKINAGAQFFQSQLITDFDRLDKFVNQIANQSDKPVLAG
IFLIKSAKNALFLNKYVPGVQIPEHIIDRLAKAKSPLQEGLAIAAEQIQTARQICQGVHI
MAIKAEHLIPEILDRAGVSVI
>A0A387GY13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. CCGE532|TrEMBL
MSSRSENRNDGIRVSFEFFPPKSEEAEQQLWATVADLSDWEPEFVSVTYGAGGTTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLAAGVHRFVALRGDPPGGVGSAYQP
HPGGYANAAELVGALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKAENGADRALTQF
FFDNDAFERYHDRVRAAGVWIPIVPGIMPIQNLTQLKRFAGACGASIPSRLDKRFDGLDE
NVEERAKVAADVAAEQIQDLIRRGIHEFHLYTMNRSPLVSAVLERLGLQRKVDARAGAAA
>A0A4S4FLH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naasia lichenicola|TrEMBL
MGYEVLPFKATEDNVVKFVPKSVRLTVTASPPKGIEATIALAEKLAGHGYSVAPHLSAKM
IRDKVQLGEFVQRLKAVGIDSVFVVGGDAEEPAGEYTDALSLLKSLDSIGHEFTSIGIGG
YPEGHHFIPQDGLDAALNEKAQLATYIATQICYDAPAIISWARRIKSEGVDLPIRVGMPG
AVSREKLLRISLASGVGDSLKFLQKQKGMFWRFFVPGGYSPNKLIRGLKPAIGAADNNLQ
DFHIFTFNELEGTEAWRKQMLQRYPSQAS
>D4C5H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia rettgeri DSM 1131|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSEEMEQTLWKSIDRLKNLKPQFVSVTY
GANSGERDRTHSIIKDIKDKTGLIAAPHLTCIDASPEELKAIARDYWNNGIRHIVALRGD
LPDNSRKPDMYAVDLVELLKSEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPAWMSKMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A5N8UTN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. YLB-07|TrEMBL
MGFHHAQHSTSLNQSLAELNGDINVSFEFFPPASPEMEKILWNSIRRLEPLKPKFVSVTY
GANSGVRDRTHGVIERIQRETDLVAAPHLTLVDASDEELIELAKHYWNSGIRDIVALRGD
LPDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDATNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDAEIIPGILPVTNFKQLKRFAGMTNVSIPGWLHKQFE
GLDDDPATRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>C2K145|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus rhamnosus (strain LMS2-1)|TrEMBL
MKISQCFKDHQVISFEVFPPRKNATNIAMRPILNTLDAVKAADPDFVSVTFGASGNKPHM
GTLEVAKLIKDEFNLEPVAHLPAAQLTRAQVDAELRGFQEAGIDNILALRGDIPKSGRVS
EDFPYACNLIEHIHQVGDFDVVGACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYQFRERAALAGINVPIEAGIMPVINEHQIERMATMAGVHLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A7S0A5N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrodinium bahamense|TrEMBL
MAGTYADDAKIADLVAKTSPGWFSFEYFPPKTEEGVQKLRNRIVRMKALKPLFTDFTWGA
GGSTSELTLQLTSAAKNEFGCVANMHLTCTNQKSEMCGEALDACKAVGVRNIVALRGDPP
RGQEKWTATEGGFTCALDLVKYMREKYGDYFSISVAGYPEGHPDNIEAVEGGVAALTESE
KRRCRVAKDEHGAEVVSVCRDANFKKEMEYLKEKVDAGAQFVITQMFLDPQVFLDFVKTC
KEYGINVPIVPGIMCLNNFGGFQRMTNLCKTRLPQGLLERAEAANTSDDAFKAFGIEYGT
EMCKALLDGGAVGLHFYTLNLERVVVGTLKGLKLITEEQAAACEGGDKDAKFMVSAQGIT
TGTSLPAGKRLPGNRPLSEADPEMAKLVQEEK
>A0A372LJ19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peribacillus saganii|TrEMBL
MEVDFRYELQNRILIGEGAMGTLLFINGIDQCYEEFNIQEPGRIERIHSAYVSAGADILQ
SNTYGANYIKLKRYGLEDKVSKINRRGVEIARKAAGKDAFVFGTIGASRSFRKSDLSIEE
IKRSFREQLYSLLMAQPDGLILETYYDLEEIETVLEIARSETEIPIIANVSLHEIGYLQN
GVHLSEALSRLEEIGADVVGVNCRLGPHHMIRSLEEVPLPAHAHLAVYPNASLPDFVDGR
LVYAAVPEYFESSALELRKQGARIIGGCCGTTPLHIEAMKRAIGTLKPVSKKTVRPRKIE
IIEAGNINTTVALANKAKNERTILIELDPPKKLGIEDFMAGADALYEAGADSITLADNSL
ATPRISNGALGMLIKNKTGNIPLIHLTCRDRNLIGLQSHLMGLDTLGLNEILVVTGDPSK
IGDFPGATSVYDLSSFDLISLIKQFNDGLSYSGQPLGRKTNFRIAAAFNPNVRYLGKAVE
RMEKKIKCGAQSFLTQPVFSENQIEEVYQATKHLETPIFLGIMPLTSSRNAEYLHNEVPG
ITLSEPVRKAMAAAANDPMKARAEGMAIAKSLAAAAAERFNGLYFITPFLRYDMTAELTK
HVRTIDNKRLVEVATHE
>A0A6L9TBI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium sp. SMB2|TrEMBL
MHSPQFSLEVFPPKRNAPVGTIYDTLDGLEGVNPDFISVTYGHGTHSDRTATARIANTVR
SEYGIPTVAHLTALYSDKDVVDQALDMFDAAGVFGVLALRGDVIEGQREVGVFEHASDLV
SYIRDRRPNLKIFGACYPEGHIECPSLDEDIRNLKIKVDAGATNLISQLFYDNEDFLRFV
DKARAAGIDVPIEAGIMPVTSAKSVRNMAVKNATIIPRQLEAMLEKWGDDRESLRRAGII
YASQQINDLVAQGVDGIHLYTMNHPGTTRRIWRNVAPLFQEG
>A0A2X0S481|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brochothrix thermosphacta|TrEMBL
MTNLRDSLKNNVLIADGAIGTLLKQHDHTHGHGPSIDALNLSQPDQIRDYHLAYLRAGAD
VIQTNTYGANTLKLARYGLEKDIVAINQAGVRLAKEAIKIHGSGFLLGNIGGINAEYVPV
HLRSTSLDDIQKVFREQLYLLLLEGVDGLLLETYYDLEELKTVLKIAREVTDIPIIANVS
IHEVGILQDGTRLDIALQELADLGADVVGVNCQLGPYHMIKALEGVPILTNASLAVYPNA
SLPTVEDGEIIYQTEPSYFKKYAERFRLQGAHLIGGCCGTTPAHIANLRKGLESTTPVDT
KVVIPLPDEVVFTKPKKFRGKRLVDKVLTETTVLVELDPPRTLNTETFFKGVQALYNQGT
DAVTISDNSLASPRISNLALAALIKERYNHSPLIHITTRDHNLVGLHAHVMGLHKLGIHD
LLAITGDPTKVGDFPGASSVFDLRSVELVQLIKRYNDGLSYSGKSLGEKGNFNVAAAFNP
NIKKLQQAYKIIQRKIDYGADYFITQPVYDVETVHQLADMLNEHNITTPFFIGVMPLLSS
RNAEFLHNEVPGIRLSDEVRDRMKQADVDNRSLEVGLEISKEIIDAILERFNGIYIITPF
QRYEISLELLHYAKKRHPS
>R6P5W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:274|TrEMBL
MNFREYIKNNRVLYDGAFSTYYAEINGKCLVPEMANIKDRETVLKIHKEYVDAGAVLIRT
NTFEANTGSLGCDKEELKSIIKAGWEIAKEACGDKAYVAADIGPIETGAVLKEYEFIIDC
FIEQGAEIFNFESFADIDDVIRPLEYLKKQKLDAFAIVNFCLNQHGFTQRGAGAERLLEK
CDGIDTIDAMGFNCGVGPIHLQNVLKKIKFNFSKPVAALPNSSYPSIIQDRMVFLDNIKY
FSDVMKDVSSMNIEFLGGCCGTTPKYIKALNDAVDFSQKPHELKAALLENSDEHKEPKNN
VFFANKAKGEKIIAVELDPPKNADTTKLMETANYLKKHSVDIITFADSPSGRTRADSVLV
STKVAREVGINVMPHICCRDRNAISMSSLLLGAHINDIRNLLVITGDPVPSASREQVKSV
FNFDSIKLMKYIENINEENFPDDKICFGGAINYARRNLDVEVRRAVEKEKAGAKYFLTQP
VYDDKDIESLKYIKSFLSVPILFGVMPLVSYRNANFIRNELPGITIPDWIIDRFSMDMSK
EEGEKVGLEIAFDIMEKVKDIADGYYFTIPFNRLSICEALLKKCC
>A0A7Z8S7F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AR13-1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTSIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A3S0R180|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. TF3|TrEMBL
MTISVNQLEEARRALEAPLFADLAGDAAVSFEFFPPKTEKMEEALWETVRTLEPFGPSFV
SVTYGAGGTTRDRTHATVARIERETSMAAAAHLTCVEASRAEIDEIAEQYWAAGVRHIVA
LRGDAPGAGGFVPHPEGYTNAADLVAGLKRLHPFEISVAAYPECHPDSRDQADDLDNLKR
KLDAGATRGITQFFFEPETFFRFRDRAAAAGITAEMVPGIMPVTNFQSIVRMSAMCGTVV
PPWMGRLFEGLDDHPASRQLIAATLAAELCRKLYAGDVRNFHFYTLNRAELSFAICHLLG
LRAKPVAAAAAA
>A0A1Y2BZ39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neocallimastix californiae|TrEMBL
MKIIKKIEKAIQQKRTFCSFEYFPPKTPQGVNNLYDRFERMALLGPEFIDVTWNAGGVTS
DLTIEICSNAQTVYGLETNMHLTCTNMPVEKIDHALKEAKKAGVQNIFALRGDPPRGVKD
WTKCKNGFSYAVDLIQYIKKNYGDFFGIGVAGYPEVHPDSPSKEDDLKFLKQKIDAGGEY
IISQYFYDVDLFLQWVKDCRAAGINCPILPGLLPIQTYDKFINMVRMNGTSVPEYILQDL
EPIKEDDQAVKEYGIKLLTEMAKKLIENGIPGIHIYTMNLERSARVILENLGLAQSQEVV
KPLPWNRSLKNNRLKENVRPIFWRNRIKSYIQRTDSWDEFPNGRWGDSRSPAYGEVNLHS
SSSFKYSNEACLNMWGNPEKPEDVFDVFSKYLKGEIKALPWCETALHAESSVIRERLINI
NKKGFLSINSQPSVNGVPSNDKVHGWGPKNGFVFQKAYLELFISTEKLDKLEQAIKDDDY
LSYYAINQKGDLKTNQKNESANAVTWGVFPGREIIQPTIVELNSFLAWKDEAFSLWNVWK
DLYENNSKAYEVIDKISNEYYLINIVDNNFQRVDKIYDILQSL
>F4NR03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli D9|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEKYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3S0VI13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium genitalium|TrEMBL
MFEASSSTRLSASAPLDREGAQLIRRPRPKRQRTALSFEIIPPRPTDDPEKIDQLIAGLA
EYKPDYVSVTSSRRSEWLEGTAAVISRISETTDLRTIAHLACTAGTRDEMAEWVRVLIDA
GVRGFLALRGDLPEEGLPADHLQYATDLLNLIQDVQEEEAFRLAAGKLALSVACYPKGHE
ESRNFDHDLDVLLTKQRLGADFAITQLFFEAQDFMEFVEVARLAGVRIPLIPGIMPMTSL
KRVRRMGELSGLEVPVGVEKQLLEADNEYEAGMQLTANLAREILDAGAGGLHVYTHNNLH
VTRDFLDRIGIDKGQQ
>A0A0C4F8N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia triticina (isolate 1-1 / race 1 (BBBD))|TrEMBL
MANLKPTCAHVTWGASGSTSDTSLEIAAMVQDQLSIPACLHLTCTNIQRSHLDQTLSQAK
ESGIVNILALRGDPPRGTEHWIPTDHEFQHAIDLVKYIRKQHQTHFCIGVAAYPEGTTEF
DQDQELSYLKQKVDAGADFIVTQLFYDVDIFLNWVKACRKLGINVPIIPGIMPIQSYDGF
RRLTALCKTNIPDSIHAKLIPIKGDDQAVRDFGVKLSTQMIKRLQANGFRSFHLCTLNLE
RSITRLVNQLGWCPGGIKHCQPLLGPSVKIGTAEIVQGGLSVGWDEFPNGRFGDQRSPAF
GLREGYGSSLTSAFSHLTTDVHALWGTPTSLEDITNVFCAFTEGKLPSTPWSEEPLALET
SSITPFLVQLNQNGWWTVGSQPAIDGADSLDSVVGFGPEGGRVYQKSFVEFFIPQSHLEG
LLSAVDDYNKDHPEGVAQLRYYAGNCNQDHIRTNVAPCETNAVTWGVFRGAEVVTTTLIE
AQSFKTWKNTYGRF
>A0A6M1NNA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. SGL-16|TrEMBL
MKIVDHIKNAKGKTLFSFELLPPAKGQGIQSIFNTMDELMEFNPPFIDVTYHREDYLYKQ
HANGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLDFLGIDN
VLVLRGDARKGDPDFIPTTGGHAYATDLLAQVADMNSGKYLHEDIENSSKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFYNIEKYKEFVVKCRENDIHVPIIPGLK
PLTTKKQLIALPKIFHLDIPEELSDAVEACKTNADVQKVSNEWMVNMCKELIEFGVPVLH
FYTMSNPGPTKRIVEKLA
>G2LNT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola str. Ua|TrEMBL
MNILSEYYQDILNQKIENIKNSIHCSFEFFPPKTNALKQNLWLTINKLTTLKPQFFSVTY
GANSGERQQTYNIVKKIREKTGIITAAHLTCVNSTPRQLKYIAEKYWNNGIKNIVALRGD
IIEKNYQHTMYASDLIMLLKKIADFDISVAAYPELHPESKNSKADIINLKKKIDAGANRA
ITQFFFNVDCYLEFRENCIKNGITVEIIPGILPIYNFKQLQRFLKMTNVTIPKWMLNMFY
GLDNDIFTQKIIGTNIAIDMIKKLSSEGIKNFHFYTLNQLDMTYSICNILGL
>A0A8H6J6S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum sojae|TrEMBL
MDKITDKIAALPADANYFSLEFFPPKTTMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
SQKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALEDAKALGIRNILALRGDPPRKDE
YRDAEDSDVDDVDDFVYAIDLVKYIRKKYDDYFCIGVAAYPEGHADESHPLGQSFEHDLP
YLVEKVQAGADFIMTQLFFDIKAYDNFERILREHPSGAFKTIPLLPGLMPIQSYQMIKRT
TKLSHAKIPDNVMARLEAVKGDDEKVKRVGVDILSELIEQVREVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDHEEEDEVAVVDDAPGAPVPTFQLNGVSPVPAGTPRALSGRRQS
SIGSDPHNRVIVSSASNPAYETTAASLTAEPVNTRANTLAISEGEGVLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVTQAVGLWGTPKTVQDINQLFVRHIKGQLSAIPWSEE
ELLPESNIIQQELLELNSRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKSFVEFFLP
SADWAGLVARLNEVKDGSICFYAASAAGDFVSSDASGGLVLEGAESSTNAVTWGVFPGKE
IITPTIIEEVSFRAWAEEAFNIWGEWAKVYGKGSESEALLERVRSEYWLVNIIHHDFVDR
DALWKLLRGEKEN
>A0A8H6JLZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum sojae|TrEMBL
MHIKAMLEESRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMFHFGPKFIDITWGAGGRIA
ELTCDMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRRAYKAGCTNILALRGDPPREKEK
WEATDDGFQYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDGDNFIRWVGKVRERGINVPIIPGIMPIATYASFLRRAKHMNCKVPEEWMTAL
EPYKNDDVAVREIGKGLVADMCRKIIAAGIHHLHFYTMNLAQATRMVLEELDWMPSSERP
LKHALPWKQSLGFGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSIKDVANIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSSHPVHGWGPPNGYVYQKAYLELLVHPDVYPEIVARIEKNP
DMTYYATTKNGALKYNSSNDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGTDW
AHCFEAGSPSRVLIDRIMNDWYLVNIVNNDFHQKTALFDLLDGLAAKEYEDIPSEPQQTN
GASKSEVPNGNSASATAN
>A0A2N1XWE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium HGW-Gammaproteobacteria-3|TrEMBL
MQTQKHYPQLFSFEFYPPKTEAGTESLQKVHQKLARLQPDFFSVTFGAGGSTRDKTYETV
IKIEQQGVPAAPHLSCVASTRENILDILKGYRDNGIKKIVALRGDLPSGMMSAGQFRYAN
ELVEFIRAETGDYFQIHVAAYPETHPQARNANEDLKNFKRKVEAGANAAITQYFYNAECY
YYFVDACEKMAIDIPIVPGIMPITNYSQLFRFSDMCGADIPRWLRKKLECFGDDREQIIA
FGLDVVTTLCQQLLDNGAPGLHFYTLNQAEPTLAILNNLDLPARS
>A0A4R6CPG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. KU 011TH|TrEMBL
MLVEYLTSLHEIYSVKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGK
ARDIQDFEHFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKNNYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDRVYLRCALQILICKH
LGFSGIHLSACHKPEEQMLLESYIEQYRHLELNVLEELWNSLWQVTTGKEFSPEIACFSR
QPTSKQIVKYRQLHVMHEAMFGSKIAKGLGRFIFKASFWENALVAKVLIKTEVLSKHSLV
GCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQT
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A1U1DBJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus subsp. abscessus|TrEMBL
MTTNPLDRDGPVAELQDPGSIADRLTAVQPGEIAFSVEFMPPRDEAAEARLWRAARVFER
YRPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWVPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEERLLRAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTARG
>I0ST04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis SK1074|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A449GAQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia paraffinivorans|TrEMBL
MRIALYTERVTPTAPAPSIVERLSAPHRGPVPFSVEFMPPRDADGEARLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSVDELRALVGAYADQGIT
NLLALRGDPPGDPLGEWVKHPDGVEYAVELVRLIKELGDFHVGVASFPEGHHRAIDLEHD
TANLVNKLRAGAEYSITQIFFDVEDYLRLRDRVSKADPEQGAKPIIPGIMPVTSLASIKR
MAYLSGSVIPPAVEERFAKAAGDGPEENREAVRAVGIDFATETAERLIAEGAPCLHFCSL
NFAKATTEVLGRLGVDVDAVLHVPA
>A0A540VMR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spiribacter salinus|TrEMBL
MIDRIRASQTKDALLQDLYEMRGRIPLSFEVFPPKSSEQCVALHDTVDRLTPLASRGFSV
TMSSGGATRDRTVDTAAAIATRTGRPVMAHLVSLGLSRDAVLNTADDLWARGIRRILALR
GDRPKGESGALPPGFDHASELVAALRKRHDFEIAVAAHPETHPEAETRDQDIEYLKRKLD
AGAGSAFCQFVLDPAAYGRFLEDCGQHGIDVPIIPGLMPLERWPRLKRFARMNGAMVPDW
LNELFARAETTPELEPYLAATMTTEHARRLIAYGAPEMHVYTMNRWPPSMALATVLGHK
>A0A663LPY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Athene cunicularia|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPVIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A1Q6YJ02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_2_20CM_57_17|TrEMBL
MKIHDFNERLKDSILIADGAMGSMLHEAVGTQRCFDELNSTEPEAVFRVHQAYIEAGAQI
IETNTFGANRFKLAPLGLGEEVQRLNSRGVKIAREARESAAREVLIAGSIGPLGLGVQSR
HPADDEILDIFHEQALALEERGVDLYVLETFSYIEELLLAIDAIRSFSGLPIVAQLTYAE
EGTIYGDLRPSDAASQLKNKNVQVIGANCTLGPQALLPILQELAAVDGLRVSGMPNAGFP
KREGDRIVYPKSSPEYFALFAREAAGLGVRILGGCCGTTPAHIRAMAEAVKSFRPAKTHA
VAHSVATVAKPAPISEREPESKFWRKLQAKKFALCVEIDPPKGLSLDRIFEQVDKVMASK
KVDAIDINSGAMARVGMDALIVAGALEARGVGTVPHLTTRDQNIIGLQAALLGAWTVGGV
RNVLAITGDPPSVGDYPETSGVYEVDSVGLVKVLHRLNQGTDWAGKTLGGATNFTIGVAL
NPVADDLDNEIERFHAKVEAGAHFAMTQPLFDPEHWHAFLKKLGSKPAIPVLIGIWPLNS
YKQALRLNNEVPGIVIPERLLKSMEAAGASARDCGFKVARDMLAWSHTELAGAYLIPPFK
RYEEILEIL
>A0A7Y7NLZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium|TrEMBL
MNNPLSNLHRKLAVSEFVFTAEVCPPKGCDTSLFIQQSKALAGVVDAINVTDNQGANMRI
SPLAASALLLREGIEPILQFTCRDRNRLALQSDLLGAAAMGITNVLALTGDHISFGDHKT
AKAVFDLDSVQLLEGIRMLQGGTDLSGKKLEGAPSFFTGAAAAPEAEPFELTLFKLNKKI
AAGAGFFQTQAIFNTVKLERFSSRLNPSGVKIIAGILLLKSAPMARFINKNIPGLRIPDE
IICELESSTNPTQTGIDIAIRLARAAKAHSHGLHIMAMGREEVIPEIIKGVI
>J5K9N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR86 cluster bacterium SAR86A|TrEMBL
MANEQVVSFLNDFSIEVTPNAAKKIDNFSDYLSPGTLIYIAHIEGTPIEETVATAKKITD
QGFKAMPHFPARIIKDKDTLKDWIGRYKNEAGVENALLIAGGANKPYGEFDSSIQLIESE
LFDKAGFKNLHIAGHPEGSKEIDPDGTTANVDQALSWKNEFSKRTDASMAITTQFCFDSN
SVIEWVNGIQKSGIDIPVHIGIAGPAKLQTLLRYSIECGVGASIKILQKRAKDITKLLLP
YKPTQIISELAAYKSSNPDFNIEKVHFFPLGGIKQVSQFVKEI
>L7KP02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia aichiensis NBRC 108223|TrEMBL
MSQASPYTGPVNSSAPVPSVVERLSAPHPGRVPFSVEFLPPKDVEGEARLWRAVRVFERL
NPAFVSLTYGAGGSTRDRTVRIAGQLATETTLVPVAHLTAVNHSIAELRSLVGAYADKGI
TNILALRGDPPGDPLGEWVRHPEGVSYAEELVDLIGDLGQFHVGVASFPEGHHRAVDLDH
DTRVLVSKLRAGAEYSVTQLFFDVEFYLRLRDRVAAADAEQGAKPIIPEIMPITSLASVR
RMVELSGSVLPVSVEQRLIAAAGSGEQEDRAAVRAVGIDIATEMSQRLIAEGVPGLHFIS
LNFAKATCEVLDRLGVDTSDALPLVSSG
>A0A2V2ADA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. OV226|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDYFHIEVAAYPEMHPQARNFEDDIANFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A4R6TJR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zeaxanthinibacter enoshimensis|TrEMBL
MKVTEHIGNAKGETLFSFEIIPPVKGHNIQELYDNIDPLMEFNPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYNVDTIPHVLCGGFTKEETEYLLIDCHYLGIQNV
MALRGDAMKEEKYFEPTSGGHAYASDLVQQIHKLNCGEYLHEVVERDHCADFCIGVAGYP
EKHMEAPSLQTDLKRLKQKVDEGAHYVVTQMFFDNKKYFEFVDAARAAGITVPIIPGIKP
VAVKRHLQLLPQVFRIDLPQELIDAVEACKNNKQVRQVGIEWAIEQSRELKQAGVPVLHY
YSMGKSDNIKAIAEAVF
>A0A8A4TUG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfidibacter corallicola|TrEMBL
MPLFNEHHPVPDPCKFPAKGTIVVSLEDAFARNLPVTSIEYNPPPVSDPRKQDLEYWKTL
QTPDMEDEKILRQLRGKLTMLRLCHERNRGFVSLTDSAAGIRRLHNLTLIRFFSDAELTH
RWFSQPPIVWEPRRVILHVTRNHDLDWLRRYLAQLGRQGFGNLLLISGDPLKGMKLPTVT
GERAISASSKEARSLRLKSSVDLLKFVADFENSFFLGAGHNPFLKASAGQRHLQRKCEAG
SKFFITQPVSYYAECWQAMSDLKSFCEAQRIEQPFILGVFNYSVPCNALGYRAETFEKRR
AFWKKLFGFVPQGVRADYDRGLDGNEILARSINKLRRMGYFHFDVMNAEKRGWRVIRDEQ
RLLHESDRLAGVFDSASLW
>A0A0S4IQL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bodo saltans|TrEMBL
MAAPQFKVSELLAAEKPEETYVSFEFFPPRTEKGEVTLMEEHMPVFAKQSPIFVDFTWGA
GGTTYDKTPALCISAMNHGMNVNMHLTCTNMEEGKVKEALDLCKANGIRNIVALRGDPPA
GQEWKASAEGFTCALDLVKYIRAHYGDYFCICVAGYPEGHPDKIHAERGVMNAEDEVHEL
SYLKQKVEAGADVIITQLFYDVNVFIRFVKKCRENGINVPILPGMLPMQSHGGLKRMVSL
CKTYLPDDVIAQTEALAENDEGFKAYGVELTTKMIRDIVDAKIGINHFHFYTLNLPHSTM
KVLDNLGMRKE
>E1IIH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillochloris trichoides DG-6|TrEMBL
MIYSNLQRRLAAGQIVVTGEMAPPKGGDPTRLLQLAQAMQPSVDAINLTDNQRGVARMSS
LGAAAILRQAGIEPIMQMTCQHRNRIALQADALSASALGVRNILCMTGDHPRIGDHPQAK
NVLDLNSFQLIRMLRKLRDEARFDSGGQLKEPPQFFVGGVANPNVERAARLEKKVQSGAE
FIQTQLIFDVARFRTWMADVRAAGLHQQAHILAGVMVLRRPHSALYLRDHLPGTLMPDGI
VDRMQAAEDSEREGISIAAELVSELLSVEGVAGVHIMSVDWTRAIPQIIERAGMLPRPDL
PE
>A0A259RCK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomonas sp. 13-64-67|TrEMBL
MRMASAQSVSPRVNLSFEFFPPKTPEGADKLRAVRQRLYARQPEFCSVTFGAGGSTQEGT
LQTVRDILAEGVDAAPHLSCIGASRDSVRGHLRDFQAAGVKRLVALRGDLPSGYGIGGEF
HHARDLVAFIRDEMGSAFHIEVAAYPEMHPQARSPLDDLQHFADKVRAGANSAITQYFYS
ASAYRRFVDDVRALGLDVPVVPGIMPITNSSQLLRFSEVCGAEIPRWIRLRLQSYGDDRE
SIRAFGREVVSSLCEELIASGAPGLHFYTLNQAEATLAVLDDLGR
>A0A2G1YWA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robiginitomaculum sp|TrEMBL
MIIEETRNNRDFHRNGHRPVPGTLARASSSGGEHINISFEFFPPKTEKMGETLWQSIQKL
ESLNPDFVSVTYGAGGSTRERTHQTVARIVKESSLKAAAHLTCVGSDKAEIDEIAREYWQ
AGVRHIVALRGDPVGGLGAPYVPVDNGYAYASDLVTGLKNVADFEISVSAYPELHPESLN
WDDELDNLKRKIDAGATRAITQFFFSADTFMRYLDKALDAGISIPIIPGLMLQPNYRGLT
RIAKLCYISIPDWYHNLFEPLDDDPQTRLLLTASTAADLAAQLRAHGVDHFHFYTLNKAD
LAFTTCQILGVKAQNTIAQKVVT
>A0A0N8W9U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp. SDB|TrEMBL
MRIDQYIACQQQPFLSLELVPPRRGGSVNDIFKTIDQLISYSPKFINVTNRCNSVIFKNC
KGKPVKTPLNNKPGTLGVSVAINQKFNIPTVPHLVVSGMDKFELEDLLINLNYLGFKNIF
VIRGDQAEPDTFLDQNPDQYQYASSLVEQINLMNQGIYSTSALNNTPTEFCIGVAGYPEK
HYQAVNFDYDLNYLKQKVNRGASYIITQIFYSFSTYVNFLKKARDIGIDVPIIPGLKPIT
SCSQLYSLPPRFFISIPTELAKNLESAKSPQQEWEAGIAYMNDLINQLLDFGVPAIHLFT
MGKNRSIKALLDQINPRLVK
>A0A2G8PB35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. 60AY4M2|TrEMBL
MALTCPPPSRFAQAIQRGEFLLTAEITPPKGSDTSTLLSLAQQLKGRVHAVNITDSNRAM
ARMSPLAASLLLQQAGVEPILQLACRDRNRLALQGDLLGASALGLRNVLALTGDPIQVGD
CPDARPVFDLESVRLLQLIQRLNNGLDCNGKPLPDGGTCLFPGAAVEPQSPSFSGLERRF
HRKLENGAQFFQSQMVTDFEQLERFMDKLGRPAGKPILAGIFLLKSAKNALFINRNLPGV
QIPDAIIQRLADAPDPLEEGIRIAAEQVRQARQICHGVHLMAVKAEHLIPHILDEAGIPP
LSS
>A0A1Q6UN37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium CAG:312_58_20|TrEMBL
MQNTGNTIAEKFGKGRTVFSVEFFPPKTEEGARQILRTANRLKKVRPDFVSITYGAGGSS
RERTLEYGELLGEIFGFEVMPHLACYGHSKSEIASILERFDSAGFRNVMALRGDKPKDGS
VSAHPDGFAHADELVGFVREKFPHFGIGCAGYPEKHPEAPDMRADIANLKRKVDAGADFV
TTQLFFDNSHYFRFVEMCRGAGIDKPIVAGLLPALSLKQLANFKAMCSTDVPRALSERLE
AAGESPDAQAAAGLEWAREQIDELLEAKVPGIHLYILNRAESALKLSEKFGGRGER
>A0A1X0WXC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. tigurinus|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADL
IQNDLAIPTIAHLPAIYLTKDMVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQILDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1Y3M2P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter agilis|TrEMBL
MPSPTYPALSYELYPPRNAEAEDSLWTTIRRLEGTRPDFVSVTYGAAGSNQETAIDLLRR
LLTETTLKPLAHLTCVGTSRAELTEIVDRLIGGGVRGILALRGDAPEGRQSRPGDVEHAD
ELVRLIREVEAQRSAQLAAGKVSVGVAAYATRHPDSPSFDQDIEVLLAKEVAGADFAITQ
VFFQASDYSRLVTRARRAGVTIPIIPGVMPMTSTRRLKKLSGLAGVDVDEALWRRLEGAR
TDDERRRVGVEATVDLARAALDDGAPGIHLYTFNEHSAALDVLDALELERPPEAGLAASM
>A0A542MY95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. SLBN-154|TrEMBL
MARTTSEHSAAARALVQDYSLEMTGKDIPGLQEAQDSIPAGTKVNVTFLGNEDLEMRVAA
SKAVKEAGFIPVPHISARRLTSAEQLQEFLARLQEVGASEHVFSVGGDPAEPEGPYEDSL
SVIRSGILQQYGVKEVSIAGYPEGHPDIADDILWRHLEDKIAALTEQGLDAVILTQFAFD
TDPVMAWIQEVRRRGITAEIRIGTPGPAGIKRLLGFARRFGIGANAMIVKKYGFSLTNLM
GTAGPDRFVTDLADLLAQNGTLGNVRLHFYTFGGLRATSEWVRDFRAPQS
>A0A241W276|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4558|TrEMBL
MSKHIPISFEFFPTKTDVGAEKLKVVHQELQQLNPEFFSITYGAGGSTRERTLAAINEFN
GKGAPVAPHLSCIGDDKGRISELLDIYQSIGINRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFQIEVAAYPEMHPQSENFDLDIKHFCEKANAGANAAITQFFFNPDAYFYFI
ERIQKEGVNIPVSPGIMPITNANNLIRFADGTGAEVPRWIRKQLAAYGDDTTSIKAFGHE
VIVKLCERLISGGAPSLHFYTMNTTNPTRQLILDLGLA
>A0A1G1E627|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium RIFCSPLOWO2_12_FULL_45_22|TrEMBL
MTVGDPEGPKGRFRNKLREKDLIVTVELSPPKGTATEEILLHADLLREKVDAFNVTDNQR
AIMRMSPLALSHLLKERGLEPILQLTCRDRNRLALQSELLSAYALGIENFCFMTGDHPLL
GDHPTGKPVYDCDSVQLISLARGLERGEDFAGRKLSGVPSFVIGAVANPLAEPLEPQLIK
LRKKVAAGIEFIQTQPIFDQEPLEKFLEMTSGLNVRFLIGITPLKSARMVEFMNHKILVK
PIPMAVAERINKAKDPVREGITIAAELMAKIKSYVSGFHIMPIGLERELPELFEQAGI
>A0A2D6KJL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTGVPERLAAGRTLSFEYYPPAGAAARRGALLTATRLARRHPDFVSVTYGAGGGDRGRTR
EMVAHIAFGHVSGRHRCPVVPHLTCVGHTRAEIRGLLADHMEVGVGDLLALAGDPRPREP
PGDFRYAADLVEFVRTETDFSVGVAAFPEVHPDSPDRVADRRHLAAKLEMADFGITQFFF
DSRDYRLMVDELSDLGCTTPVLAGVMPVTNPESVKRFANMNGTHTPKELWNRLEAADADE
RLRIACDQAASMIADLVEMDVPGIHLYSLNVPEAVEGVLDRLGEGYFSTAG
>C8N7U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cardiobacterium hominis (strain ATCC 15826 / DSM 8339 / NCTC 10426 / 6573)|TrEMBL
MTITPEDLQALIRDYSIEITPKAAQKIGDFRPWLTEGTQVYVPNLRGTKISDCIDTCELL
QNQHMCAVPHIVLRNYRSEDELRQTLDRVQALGIDRILLLAGAASQPLGPYDSVMSMLKT
GLLQHYRFAHIGFAGHPEGAADIPRADQEAAEAQKQGYALTYPGDYAFITQFCFQMPPIA
AWLEHLQARQITLPVHIGIPGVASLQSLLRHAQACGIGSSMSFLWKNARNVRKLMSLSTP
DKLLCDLAAHRRDHPDSALRQLHFYPLGGFETTINWLRAIEAGRITLTAEGFTTHE
>R6LQD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:253|TrEMBL
MYNILEKIELPADKTLIAVPNAGYPVLTRNRMEFNSRPEYFAEKTRELLSLGADIIGGCC
GTSPEFISCLSEITGMDIKSEKHIEKSIAATAKNPVNCGFLYDETGRKKEKKFIAVELIP
PFNTDDEKLLESAHYLKNAGVDVLTFPDSPSGRTRVDSVLMAAKVYRETGIEVMPHVCCR
DKNAFAMRAMFMGAKINDIKNFLIITGDPVPASARNLVKSVFNFSSVGLMKIAQEMNKEV
FNDNPLNYGGAINQNLINLDSVINTTKRKIEAGANFFLTQPVFSKEEAKRLRKIKEETGA
CIFAGIMPLISRRNALFMKNEIAGINVTDEIVERYPENGSKEEGEKVAVELAKEIISYID
DFADGYYFSFPFNRVYLLNRILG
>A0A3C2B2J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSDLLAAGPTYSFEFFPPKHEAGWLSLGRAIAELEHLHPDFVSVTYGAGGSTRTKTADLV
SWVRRQTSIPPMAHLTCMGHTRAEIRSILTDYRAENVENILALGGDPPKDGDVVSDYRYS
LELVADVQEFGGFSVGVAAHPEMHPRSTDLAADRRHLADKLRVADFAITQFFFDIEHYLR
MRDDLAALGVHKPIIPGIMPISNLGQVSRMAHMSGAEVPAWVVERMSKADDDLDEAERIG
VDIATELSARLMEEGAPGLHIYALNRSWAAREIFRNLGLRPTA
>A0A1I4A8H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shimia haliotis|TrEMBL
MTTPQVSFEFFPPQNLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNASKEETLKIANDFAAAGVSELVALRGDPPKGASGFVAHPDGFANSV
ELIEALSATGDFTIRVGAYPEKHPESSDMQADIAWLKRKIDAGATEALTQFFFEPESFLR
FRDACADAGIKAPIVPGILPIENWKGVRSFAKRCGTTVPAWLEDAFAKAERDNREDLLAT
AVCTELCSDLMDEGVDALHFYTLNRPELTRDVCHALGVTPQVRLENVA
>A0A1H9G8R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loktanella sp. DSM 29012|TrEMBL
MTRPAISFEFFPPKNIAGSFRLWDCVNALSPLAPEFVSVTYGAGGTTRQLTHEAVTAIDK
TTGLKVAAHLTCVDATREETLAIANEYADAGITDLVALRGDAPKGSDGFKPHPEGFASSI
ELIEALADTGKFTLRVGAYPEKHPEARSQADDIAFLKRKIDAGASAAITQFFFEADTFFR
FRDACVAAGITAPIIPGILPVENWKGASKFAAATGTSIPPVIAQAFENATRDGSADLLAT
ALATELCDELLQGGVDHLHFYTLNKPQLTQDICRALGIAPQARLQNVA
>A0A7G1IV02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A848TM02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Silicimonas sp|TrEMBL
MSEPTVSFEFFPPKSLDASFQLWEALRSLRHLDPSFVSVTYGAGGTTRELTHEAVETIRD
HTGVEVAAHLTCVNASKDETLEIAQRYAAAGVSKIVALRGDPPDGSEAFEAHGDGFASSV
ELIEALASVGTFDIIVGAYPDPHPEAGYEDADVDWLKRKVDAGATSAITQFFFEAETFLR
FRDRCDAAGIDIPVLPGILPIQSWNGVRRFAERCGARIPDTLALAFEAAERDERSDLLAL
TQCTTLCTRLLDEGAGHLHFYTLNKPDLTREVIHALGLAPAAVLENVA
>I0L8Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora lupini str. Lupac 08|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTEVGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATDTTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPEGVDYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAQFVR
KCRAGAEFAITQMFFEADDYLRLRDRVAAAGCDTPILAGVMPVTQIATIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQASDMCRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARV
>A0A1W1D5Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MFERLIEKLKNERYITLETTPSHSATFLPIVEKIKELGLDELVDGFTTTDNPLAKLKYNA
LFGAKLLQEQLHKPVIATMSMRDRNKIALQSDLLGANEFDIRAILALTGDPATMSDQPRT
KGVFEADSTLLLDIISAFNCGMDYAGKPFVQKPKPIYPFAVVNSFAKNSKTLQKKMHKKI
KHGAIGIITQPVYDMENVKLLLELLDNANNECCNGEKKAELIIGFFPITKLRTAQFLSAH
VPGIHVPVSWIEALREANINGGADEEYKVGFELSKNLFDEIQKHHPKVHLMTSNQFQIAK
DILQG
>C6S6L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis (strain alpha14)|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A7X1UT54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETITDLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A848QIJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontixanthobacter rizhaonensis|TrEMBL
MSNRSFPRLDEMREAQTALDTPLFSGLPGDITASFEFFPPKSEKMEAQLWASVQELAPLN
PSFVSVTYGAGGSTRERTHNTVARIIREAGLPAAAHLTCVDASKAEIQEVAEQYWEAGVR
HIVALRGDAGEPGAPFVPHPDGYKSAADLVAGLKNIADFEISVAAYPETHPDADCPQSDL
DNLKRKLDAGATRAISQFFFSADTFFRFRDDAAAAGITQPILPGILPVTNVAQARKFAGA
CGAKIPDWMDGLFEGLDERPASRQLVAATVAAELCRRLYAGGVRDFHFYTLNRADLAYAI
CHMLGMRPQASNAGDAA
>A6QT35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces capsulatus (strain NAm1 / WU24)|TrEMBL
MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTWAVDLVKYIRRTHGDYFCIGVAAYPEGHSDESYPEVQDPVKDLPYL
IEKTRAGADFIMTQLTYDLGAYKRFEEMLRNHESGVFETIPIITGLMPIQSYHILTRTTK
LSHARVPPDIMARVEAVKSDDEEVKRIGVDILCEIVNGLKQVSYPGPRGFHFYTLNLEKA
VALTVEKCNLIPPLSPLSDSETYMDTAVFMAQGKQNGISLLSKRRASSMNSQPHNRLIVD
RPSDAGGSSQASTTHETPALGAGMPALNPPPRTTTLQISEGVGALGREATWDDFPNGRWG
DARSPAFGEIDGYGPSLHVNAAVARRLWGYPTTKQDINNIFQRHVSGELHLVPWSEGGAQ
DTGGLNAETATIRDELLHLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAFV
EFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSSPATDAATEDFSGPVDVFLDS
NVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIFPRGSPTERL
LDQLKNDVWLICCVGQKYGAGCASLEAAEAEGKLLWKLLGGTGTEPDSVDKH
>Q10BJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryza sativa subsp. japonica|TrEMBL
MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLK
QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNL
GLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLD
QLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWK
DEAFEIWSKGWACLFPEGDSSREILDKVIRHKP
>A0A4P2R5A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
MVSKSKMERLLSERQFLVSAELTPPRHYDLEKLLKHARNMAGCVDVVQINDHLLSQARCA
NMAVGHFVKQEGLEPVLQFSLRHKNRIALQGDLLGMAALGLSNIIILGGYPCAIGSDPDA
KEVSDVDSYAAIELTRRMTREGKLYNGDVISPAPYFHVGTIDFPCAEQAIAGAMDRLSAK
IDAGASFIQVQAVFELAPMRRWMAAVVERGLHERAHFIAAIFPFAGVDRLSFLQKVPGLV
VPDHLIERVRRSGDAEGESYRITLELIRGLRDVPGLSGIHMRSIGAEDWVPRLVEEAELR
RAA
>A0A0H0XLF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantiacibacter marinus|TrEMBL
MSVQAPDCLDPVQEKRTARDTPLFSGLPGDIAVSFEFFPPKTDKMEEKLWEAVQELAPLA
PEFVSVTYGAGGSTRERTHNTVARLIKEAGIPAAAHLTCVDASKAETRAIAEAYWEAGVR
HIVALRGDAGEPGAPFVPHPEGYANAAELVSGLKEVADFEISVAAYPETHPDAQCPQSDL
DNLKRKIDAGATRGISQFFFAPEVFFDFTDKCRAAGIHAPMVPGILPVTNVAQARKFAGQ
CGAVIPDWMDGLFEGLDERPAARQLVAATIAAELCRRLYAGGVRQFHFYTLNRADLAYAI
CHMLGRRPVERGPMEKKS
>A0A3B1D4B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MNKIIDIFKQKEKTLSFELFPPKTEKGYENLLTTIEQLSALKPDFISCTYGAGGGNRDKT
FDIVQLLQEKYNIVGLAHLTCVLNTKEELKNILTDAKTRGIQNILALRGDPPVDNPDWQP
GENNFKYSSELCAFICEHFQDYFGIAVAGFPEGHILCPDRNKDAEYLKLKFDNGADFVMT
QLFFNNQDYFDYVKRLRKVGVKASILPGILPITNYQGLLKFTATCGATVTQEVKDIFEPI
ADDKEAVLKAGINFAVKQCQDLLAGGAPGLHFYTLNKISPVDKILSQGHICAAFPR
>A0A160V7R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MSLASSTAIWPDAMIRCRRGDFPLSRATIFAGTITFYRRAESVGSCWIPSLKIKDILTKT
RPVSFEFFPPRQAEGIPAVLETLDELKQYLPDFVSVTYGAGGSTRAFTEEITFEIKRNTD
VEVMAHLTCVGQNKEELDEVLSRLQEKGVENIIALRGDPPKGTTEFVPVEGGFQHATDLL
HYVVSNYKFGVAAACYPEGHTESVDLDADLEYVKMKVDNGADFLVTQLFYDNRFYFDFVE
RARAEGIEVPIIPGVLPVLNSAQVRRFTTLSGSKIPLDLDKLLDKYADSDHSARDMGVEY
ATAQVRELWDSGVPGVHFYVLNRSYSVSRILDNLQIAGHQRQD
>A0A1S7P5T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium deltaense RV3|TrEMBL
MLRSETARQNGDIRLSFEFFPPKNPEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLATAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYK
PHPEGYENAAALVKGLREIADFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A446A448|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. JV551A1|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSAERFAAMDEILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFGNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSRQATPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGMPAVSFNPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPMWATRLGAQVLHKVEHAVKKPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTSLNSCEFGDRECIHSVKYRTAKAVRQTALLTERLIPCIEVETRHRSSWPQWFAPHTP
RRLSPQPAPRTQPE
>A0A7X9ZR54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium psychrophilum|TrEMBL
MTLNDPAAPLYADLAGDAQVSFEFFPPKTEKMEAQLWSAIETLAPLAPKFVSVTYGAGGS
TRERTHNTVARIAQETPLAAAAHLTCVGASRQEIGEIADAYWEAGVRHIVALRGDPPEVG
GTFEPHPQGYSGAADLVDGLMKRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFSPEAYFRFLDKTAAAGITADIVPGIMPVSNFAATQRMAAMCNTQLPSWMARLF
EGLDDHPGSRQLVSATIAAELCRSLYTGGVRDFHFYTLNRAELSFAICHLLGLRAKAAAD
VTL
>A0A7S0MH06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptomonas curvata|TrEMBL
VKISDKIRASNGQPFFSFEYFPPKTPSGVQNLYDRVERMGKLEPLFVDITWGAGGSTSDL
TLELSANFQQQFCLETQMHLTCTNIHKESVTEALLRCRKAGIQNILCLRGDPPQGQEKWT
ATEGGFANAVDLVKYIRQEHGSYFGLSVAGYPEGHIDWFKDTPEISEESYRKDLQYLKEK
VDAGADCIVTQLFYDVDNFFKWVKDCRDIGITVPIIPGIMPINTYAGWERMTGLCKTKIP
PAMREALEAIKDNDEAVKAFGVQFVTDMCRRLLDGGCCGLHLYTLNLEKSVLQILRNLNM
PKDSIARRSLPWRPRLTEGRRQEEVRPIYWTNRPRSYLSRTLHWDEFPNGRWGDNRSPAF
GELSDYHLCELHTVDVEERRRLWGAELASERDLREAFALYVEGAKPRLPWCARLDEETVG
LQGELARLSRNGLLTINSQPRVNGSPSTDPVYGWGGPGGFVYQKAYVEFFCSPAHLAAVR
AAVAHRPSVQFSAVNKRGELEMSCESKVMAVTWGVFPDREVVQPTVVDRDSFLVWKDEAF
GLWESQWGALYPKGSPSAAIIEAVVSSYYLVTVVDNDYVAGDLFGLLVTATDKM
>A0A7K3HJD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5475|TrEMBL
MSTLGEILAAGERTYSFEFFPPRTETGERALWHAVRRVEALAPTFVSVTYGAGGSSRDRT
VRMTERIAAETTLRPVAHLTAVGHSAAELRRIIGQYASAGVRDVLALRGDPPGDPRGPWV
PHPRGFRHAGELVRLVRELGDFGVGVAAFPERHPRSPDWESDIRHFTAKCRAGADYAITQ
MFFHVEDYLRLRDRLAAAGCATPVIPAIMPATDVRQITRFAELSGAAFPPDLARRLEAAR
DDPAESRRIGVEHATEMALRLLAEGAPGLHYITLNRSTATLEIHRNLGLPLGGPRTAPAA
A
>A0A1H4JJU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terriglobus roseus|TrEMBL
MPETISQSKTHDVERLFGPSPVLCDGAMGTMFYARGVFINRCFDELNLTDPQMVRELHEE
YLLAGAEVIETNTFGANAARLKRFGLEGKVAEINTAAVRIARAAVNGVREKHAHQAFVAG
ALGSLGFDKKDADPAMMLAAYTEQVNALVAAGVDLFVVETITSLAQAKAAIQAARDAAPE
LPVIAMITVTDAGIVADGTSPEDAARLFEEWGARAVGCNCSDGPMQVLDTIERMRKVTKL
PIAAMPNAGLPNCVDGRSIYLSSPEYLASFARKAMRVGATIIGGCCGTTPKHIKAMRSSV
KAIQAQAEGVLSAGAKPAASAIEPVPLAERSTLGGRIARGEFVSMVEIVPPKGIDATREL
EGARMLKELGIHAINVPDSPRASTRMSAGSMCLQIEQKVGIETVIHYTCRDRNLLGIQSE
LLGASSLGLRNVLCLTGDPPKMGSYPDATAVFDVDAVGLTRIVRDMNHGLDIGGNSIGSS
TGFVIAVAANPGVPDLDAEVRRFAAKVEAGAEFGITQPVFDMRLLETFLKRIESFRIPIV
AGIWPLTSVKNAEFMKNDLKVRMPDEILSRMAAHAETPEHSRAEGILIAQEMLSEARSMV
QGVQVSAPFARYAAAAEVLQAML
>A0A1E3J5Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus depauperatus CBS 7855|TrEMBL
MTKLTDLIASRREPFHNFEFFPPLTEAGLVNLLDRIHRLTSSPLPRPLIVSVTWGAGGST
SDKSLELAERIFKMGVEVMLHLTCTNMPKEKIDFTLQRCKEIGIQNILALRGDPPRSEEY
AISTPLPDFFKHADDLVRYIRAEHGSYFCIGVAGYPTLHPDSKSEEAEFKWLKVKCDAGA
DFIVTQLFYDTEGFLDWVKTCRAQGISSPIIPGIMPIQSFASFKRLVNLTKTPIPFSITA
DLQPISADDAAVKRYGAELATKMVRRILDSGLVSGVHFCTLNLEKSVWTILDNLGWMEER
HGKSAPRNKVIENDGHSDGISMNGKAPNHAASHTSNLSISPSEASYIAQLGFHTLPPAPK
NGLGTQGGNNGEDSWDEYPNGRFTDVRSPAYGEIDGWGSGLKITGTQVLKEWGVPTSVAD
LSALFISYLRSDIQAPTTPFCDLPLSPESHLILPHLISLNSTESQHWTVGSQPAVDAAKS
EDPVFGWGPRGGYVFQKAFVEFFVREDEVKRLEEKVKLAGGTITMYAANKAGGFKSNTES
DAVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFSIWTDWSLLYPPHSPARKLLEEIAS
EWWLVSLIHHDYKDKEALWNFLLKDQN
>A0A2T2TF14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QS_8_68_15|TrEMBL
MKVTERLEQADDPLISYEIIPPKRGGSAEQIMGVVEELMPYDPAFIDMTSHAAEVEYVES
GDGTWQRRVTRKRPGTIGLCAAIEARYGVDTVPHLLCKGFTREESEDALIELNYLGVDNV
MALTGDDPGYKKDIAPGRSRNEYAVELVEQINDMNEGTYLDKMAEAAPTDFCVGVGGYPE
KHIEAPNLTWDVLRLKRKVDAGADYITSQMFYDNEAYFEFVEKCRDVGIDVPIVPGLKVL
SKKRHLQFLPSFFHLSIPEALAAEVEAADDREEVERIGVEWAIQQAEELMDAGAPAVHFY
IMSSARLAKRVVAPLRETLRKKKGRSRSTTPAVEDDPALVEDEEGTQEG
>A0A0Q0ICA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. P1-25|TrEMBL
MALSLQEKIEDTNQGVYLIGTTPPKIGTDKVQLKIIAEKLLARLHEIEYDGVIIYDIQDE
SSRTDKARPFPFKQTVDPREYSHLLRNLSAPDVITYKSVAQRGVEEFKGWLDETKNDYDL
KNVVLVGSPSSVGDIKLSLPNAYKTLAEQSDDFFLGGVTIAERHASKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGITPKRIILTFTPCGGDKTLEFMQWLGISV
PEATKWRMLDAENTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKATMELNLAEKQIA
>A0A0Q4DRG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Leaf203|TrEMBL
MTSLPLIDACPKGMEYGPCGGVGFDGSCEIDATHRCAFLHRPTVPWTGVDRAVVPAPSPR
TAAATQTLAALDTRPWVVADLPARALSVSSIDACAEILAGEVDAVLAGDAGSARVQFPPA
YRAHLLQRRGLRVWTGLNMRDRNRVAIEGELAALAVEGVAGVHCVTGDHTRTGHRPDAAP
VFDLDSTEAAALARAAGHVVSVAASPAAPPVDRRAARLREKVRAGADVCFVNHAGGAEPV
RRFVEDVGGGLRFIPCVPVVVDHASADLLESFTALVLPEGFLERVRGARDPRAEGIALAV
ALAEEMLALPGVVGVNLSGGRDGAEDSYAEALVEVARRLR
>A0A602Z3A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Pensacola|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A525KCD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium sp|TrEMBL
MRRRRTDLGDAVLGPIARAGIGAAAKPRVSFEFSPPKTPEAEETLWEAIRRLEPLDPTFV
SVTYGAGGSTRDRTHRTVLRMLKETTLKPAAHLTCVEASRVEVDEVIQDYWDAGIRHIVA
LRGDPPGQIGGAYTPRPDGYTNATELTAGIRAIGDFEVSVGLYPHVHPESPSIDHDIDVL
KAKVDAGATRAITQFFFDLDGFLRFMERVRKAGVTIPISPGIMPVTNFKGLKKMAGPMGV
ALPGWLGNLFDGLDKDPETRRLLACSVATEMCARLAEEGFSDFHFYTLNRADLTYAICRV
LGVREPETPQALGKEAAA
>A0A522CQX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium sp|TrEMBL
MSPAETALGPVARAGAGQGPRPRISFEFSPPKGPKSEESLWEAIRRLEPLNPEFVSVTYG
AGGSTRERTHRTVVRILKETSLKPAAHLTCVEASRAEVDEVIRDYWDAGIRHIVALRGDP
PGSLGGVYTPRADGYQNATELTAGIKAIAPFEVSVGVYPQIHPESPSVDHDIAVLKAKVD
AGATRAISNFFFDIDGYLRFVDRIRKAGVDVPILPGIMPVSSFEGLRNMSGRIGVAIPPW
LANHFEGLDADPETRKLVAASVAAEMCAKLAEEGFSDFHFYTLNRADLTYAICRILGVRE
TPTAEPKEAAA
>F0CBR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas gardneri ATCC 19865|TrEMBL
MYHPITTKARQKILIYPDTPSLASTVTDAYSLEVSATDIPGLTAAAPRIMRGSTIAIPYL
PSQDNDARLAAAQSVRALGFAPMPHLSARRITSLEELHAFVRRAVDDAGVERCLVIAGDA
PSAIGPFPDSVSLITTGVFERAGIKTIGVAGHPEGHPGMPATDQWDVLERKCRSIAERGM
APLIVTQFAFDADIVLTWLEALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACASML
SKYGISIGKLFGSAGPDCFVDRLATGLTEAHGDVSLHFFPFGGIAQSVAWVEQYRSRTAA
HIL
>A0A2N6UJ31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerococcus hydrogenalis|TrEMBL
MNIGSKDCVLSFEVFPPRKNLPIESIYNTIDRLIDLKPESISVTYGAAGNDTSKRTFELA
GQIKKHGVESVAHLISIGLSEDELTRKLKILKEKNVNKILALRGDIPKFSYEKGDFDHAS
DLIRSIKEKGNFYVMAAAYPEGHIDSPNLVEDIKNLRKKVDAGCDSLVTQLFFDNEDFYR
FRDMCDLAGIDVPIQAGIMPVINKKQIEKMISLNGIKLPKKFLKIMKRYEGDKIAMRDCG
IAYAVDQIVDLISSGVEGIHLYTMNNPYIAEKIHESIKNLIKL
>A0A3N1CRD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinocorallia herbida|TrEMBL
MTSARPTIRELLASGEKTFSFEFFPPKTEQGLLNLWRAIREVEALHPSFVSVTYGAGGGT
RDTTVDIVERIATDTTLTPVAHFTAVNHSMAELRNLVGRFASVGVNNILALRGDPPGDPN
GEWIKHPEGVEYAGELVKMIRACGDFSVGVAAFPYKHPRSPDIATDTRRFVEKCRAGADY
AITQMFFRAEDYFRLRDRVAAEGCDIPILPGIMPVTQLSTITRSAQLSGAPFPADLAERF
HALGDDPEAVRNLGVEHCALLSQELLEGGAPGIHFITMNRSTATREVFGLLGAAAARPRA
AV
>A0A3S3AH26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus spongiicola|TrEMBL
MDRIRSSASGRIPFSVEFSPPRDEAAEARLWRAVREFERLNPAFVSMTYGAGGSTRDRTV
RVTGQIAEETTLFPVAHLTAVGHSIDELRAMCGAYADRGISNILALRGDPPGDPLGAWVK
HPEGVEYAEELVRLVRDMGDFHVGVASFPEGHYRAPDLEHDTRYLVQKLRAGAEYSITQM
FFDVEDYLRLRDRVTAYDPEQGEKPIIPEIMPITSLRSARRSLELSGSHLPSVLDERLRR
AAGDGPEEDRAAVREVGIEVATEMAERLISEGAPCLHFITLNFARATSEVLANLGMSTSA
RV
>I2JVC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brettanomyces bruxellensis AWRI1499|TrEMBL
MKVTQKLEGAHNDEXSPASFSFEFFTPKTSQGVQNLYDRMDRMYNLNPLFIDITWNAGGR
LGTLTAEMVNVTTTVLGLETCMHLTCTNMGLEKIDAALDSAYKCGCENILALRGDPPLDG
SESTGVFRYAKDLIKHIKSKYGDHFCIGIAAYPEGHPEEHDISKTIKYLKEKQDAGGDFI
MTQMFYDVDIFIEWCKKCRASGITIPIIPGIMPISTYASFLRRAQWCEIHVPDHFFEKT
>A0A013SHH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 826659|TrEMBL
MTLADRVHSDHDIAPLEASKSYPDSIDKVLHFSGKARDIQDFEHFLEQAQTANIQNLLLL
TGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLH
KKIKAGADFIITQLGYDIEALKQAKSFLTKHAYSQQILACVMPLTLGRANFMVKHKVAGI
VITPHMLKVLADEKQAGHTDRVYLRCALQILICKKLGFVGIHLSACHKPEEQMLLESYIE
QYRHLELEALKELWNSLWQVTTGKEFSPEISHFSRQPSSKQLIKYRQLHVMHEAMFGSKI
AKGLGRFIFKASFWENTLVAKLLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGL
ANGPCGGTTLDRCEFGDRECIHSVKARLAKAVEQTEILKEKLIPTVPIETRGTSSWKNWY
LATEA
>A0A7G9Z332|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon ANME-1 ERB7|TrEMBL
MGDEVYSDLMRELREGEYVFTGELEPEKAGDVNEPIEMARELVGMVVACNVTDNPQSFAY
VNSMAASYLIQKETGMECVYQLRCSDRNRMALLSDVLGAGALGLKNILALAGDHVSLGDT
PDAKPVFDLDSTTLIKLIRTMVDEGKDLGGNEIHNPPKLHVGGAAAPGAAHLKAEVGKVK
RKINAGVEYLQTQVVYYTDVLDKFFDELGKVDVPILVGIFPARTFGQADFFDKYVAGVDV
PPDYLEAMRKTKEIKDKDKKKEEVDRVNIEFFTGFLEHLKGTPAAGCHMMAVGYPRIIPP
LKKIME
>A0A316YFZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acaromyces ingoldii|TrEMBL
MSSSLPSSAPQPSTPPGQTERHTDWKITTKIAKAEAEGRIWWSFEFFPPRTAQGLTNLYD
RIERMSQLGPEFVDITWNAGGRTSDLTAQLVKTVHSYVGLETCMHLTCTNMPRDKVDTAL
REAKEFGCRNILALRGDPPAGSSEWEPHAAGFTYAKELVEYIRKGYGDYFAIAVAGFPEG
HPESKDGRELEMERLKAKIDAGADFIFTQMFYDFGIFERWVKDVRAAGITCPIVPGVMPI
QTYGGFQRATARFRTIVPQYFHDALDPVKDDDQKVREVGTKLVGDMCRKIVDRNRGLGIS
GLHIYTMNLERGSRMLLEYLELEPSVQQVKHLPWTLSLTPKRRDEGIRPIFWANRAKSYV
DRTETWDEFPNGRWGDARSPAYGDVDAYGVKLRYSNEEALELWGEPSSLHDVKELFKKFC
RGEVKALPWSETPVAKETFVIDDKLQQLNGHGFLTINSQPAVDGAPSDDPVHGWGPKHGY
VYQKAYLEFFVAPSQLEGLIARIESNPKMTYHAVNAKGDMRTNTTSEAPNAVTWGCFPHC
EIVQPTIVESISFLAWKDEAYEIGRHWARVYEPNSTARKTLEDIFSSYVLVNVVHNDFKD
REGIFEPFLAEAAAAASSAPKVNGFA
>A0A0H1RNE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYENIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFRFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>A0A3A4ASU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bailinhaonella thermotolerans|TrEMBL
MSLGRSSVLPGRPPTIRELLAAGGRSFSFEFFPPKTEDGERNLWRTIRELEALRPTFVSV
TYGAGGSTRDRTVDLVERIATETTLTPVAHFTAVNHSVRELRHLIGRFAEAGVRNILAVR
GDPPGGDPLGEWVAHPEGVHYAEDLVRLIRQSGDFCVGVAAFPYKHPRSPDVDSDVDYFV
RKCDAGADFAITQMFFRAEDYLRLRDRVAARGCDVPIIPGIMPVTQMSTIARSEQLSGAP
FPPEVAARFEAVSGDPAAVRRLGVEHGAELCQRLLDEGAPGIHFITFNKSSATREVYRRL
DGWTASGSRAPMIA
>A0A117L410|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga sp. 50_1627|TrEMBL
MKLIDKLKEGPILSIEVLPPNRGHSVEEIFRTIDQLMEFPISFINVTRHAPELAYIESDG
QIVRVTKVKRPGTVGLSAALMHRYGIDVVPHVICYGMDKYQIEDLLIDLHLIGISNVFVV
RGEYENPLSGQQDRSSYKHAVELVQHIANLNRGVYLYPTEGSEPTDFCIGVAGYPEKHFE
APNMEEDLMNLKRKVEAGAHYIVTQMVFDVEIYRRFVQMARNFGIHVPIIPGVKPVVNLK
SIYSIPKKFFVTIPASFVSQMHQARSSEEEFIIGVRFAAKLAEDLLVAGAPGIHVFTMGR
AKATKAMLQLLYSRQA
>A0A520WWI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MNIRFDNKPRVSFEFFPPHSEKMEATMWQSIDRLAVLEPDFVSVTYGADGSTRERTHNAV
ARIITETSLRAAPHLTCVGASRGEIDDIAREYWDMG
>A0A258JCF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium 32-65-25|TrEMBL
MSLTLNQMAEAARALNGPLFADLPGDLAVSFEFFPPKTPAMQESLWQAVETLVPLAPRFV
SVTYGAGGSTRERTHATVARIVQETPIPAAAHLTCVNATAEELDRIADEYWAAGVRHIVA
LRGDPPGGEAGFQPVPGGYASAAELVAALKRRHDFEISVSCYPETHPEAGSLAADLDALK
AKHDAGATRAISQFFFEPDTFFRFRDKVAAAGLDIELVPGILPVSNYANLKKMAVSCGTH
LPEWMGRLFDGLDDKPAARQLVAATVAAEMSRRLYAGGVRHFHFYTLNRAELSYAICHLL
GVRPAQELAA
>A0A2H1J9X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium iodinum ATCC 49514|TrEMBL
MTLLTIGSRELLKNFSLEMTAKDTESLETASRSIPAGTAVNLTYLANETTEMRIEAAQAI
VDAGLSAVPHISARRLTSADELRDYLERLSAVGAVERLFLVGGDPSTPVGPFPDALSVIR
SGRLGEFGVREVGITGYPEGHPDIAEATLWDALEQKLAALDRAGIEASVTTQVSFDSTAV
AKWIAEVRGWGIEVPIRVGVPGPAGIKRLLGFARRLGVSANAALLKKYGASVTNLLGKST
PATFIERAAEEFARENVGDVRIHFYTFGGLVATAGWTRDYLADSGRRESRSLSQGESDAD
AS
>A0A7C7VKH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteriaceae bacterium|TrEMBL
MKTQFLERLNEKVLLGDGAIGTFLYEKGIDLGTNTDLLNLSDPDLVYSVHEEYIRAGSEL
IETNTFGANRYKLHRIGQAHRVAEINRKGAELASRAAGTDIFVAGSVGPTGIKFPLEGEE
VDNSTVEEIFREQMTALLEGGIQVFMLETFTYLDELIICIKTAGKLADYIPVVAQMTYPA
RGRTAVGNDALLCAEKSLEAGASVVGTNCGRGVRAMLSAIDRLSVLKERVPLSAFPNAGI
PEVVEHRMVYSTPPAYMADKLSEMVKQGVRLLGGCCGTTPSHIHAFRERLHLKRPRSVSV
ISGTRQTVSAEEPREKFKGKGGLLESFVPGRVPVLVELDPPSHLDLSRIISGAMALSAAG
ADAITLAENPLAVLRSDNLSLAHMLKKEIGIQTVLHLTCRDRNVLGLQTQITGAYHLGLE
AILAVTGDPATSSDQPGVSGVFDVNSLGLVRMIDQFNRGFNFAGSPMGRKTNFSIGVAFS
YRPKNPDLQIRRLERKAAQGAHFVMTQPLFDRSAVEEMADKTKHLGLLIFPGIFPLISAR
NADFLHNEVPGISIPGEIRKKLWRYDKVADQKKAALEITGRLVEDISKIVDGYYIISPLN
KWDVAELFVRQIREAGWTGSGLADKFAVSSGSGDSVREGTQLING
>A0A7C7VZ68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteriaceae bacterium|TrEMBL
MRSFRRHLYEKDFVVTFELVPGRSTRTRRYRDIIGFAEKVAEDGLFDALSITDNAGGHPA
LAPEALGRELKRMGHEPIIHFSCKDKNRNKIESDLLDLDREGLHNLLILTGDYPRYGYLG
RAKPVFDLDSVSLLRLISELEKGFQLPPEVPGGGITLPPIPFFPGCVVNPFKWSEAETLT
QYYKLLRKLRAGARFVITQVGFSARKFQELKFFLEEEGFGEVPVLGS
>A0A8J3EQM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Egicoccus halophilus|TrEMBL
MPRIDELLAAGTTFSFEFFPPQTDAGERKLRDTLNELEPLGPSFVSVTYGAGGSTRERTH
QIVVDMLERTTMTPMAHLTAVCHTRDELAAILARYRDAGVQNLLALRGDAPRDVAPFWEL
ERAVDLVELAREVGGGQFAVGVAAHPEGHPASHDLTDDRRHLATKLAAADFGVTQFFFTV
EDYLDMVEQLAGLGCDTPVVPGVMPVTNLRQIERFAELSGAVFPADLARRLHAVEDRPDE
VARIGTEVATELCQRLLDAGAPGLHFYTLNSSTATREIYANLGLPVAG
>A0A4V2LSV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4173|TrEMBL
MPLLTDSLQNQPFSIFLEYLPTKHAQPVPSCIAGYPVTMTIADRVRSDDDPEPLAIAQNY
AAEIPKILHFSGKGRDIADFNEFIRMAQVHGYSNVLLLTGDKLKHHQNGQDINFSRTRYL
ESVNAVMQSKKLAPAIKVGVALNPFKYAKAEHDAQYYKLDKKVLAGADYVVTQLGFDLDA
LKEAKQYLENQHSQVDLFACVMPLTAARAEFMVKQKVAGIVLPPHLLQLLKQEQVVDAAL
AEQNVYARCALQILICRYWGFAGVHLSACHKPEEQQKLEQALNRFRDLSFDQCMLIWSEL
HQLKSGDELKPKPDVFQKKVSPEQVLKYKSMQFMHDSMFDSKIARNVGSKFFNPKLWSGR
FANKLLIKSEYLSKHGVVGCESCGQCRLADTLYICPETCPKGLANGPCGGTTFDRCEFGD
RECIHSVKARLAQQVNQIEVLKTRMIDTVPIESRGTSSWVNWFNPK
>A0A859IEF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaesserella parasuis|TrEMBL
MSYAKEIDLLNQSVADLNGKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERNRTHSIVKTIQQETGIVAAPHLTGIDAPLDELRAIAKDYWDSGIRHIVALRGDEP
AGYTKKPFYASDLVKLLKEVADFEISVAAYPEVHPEAKSAQSDLLYLKQKVDAGASRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMAKMYQGL
DDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGVRPE
>A0A1Z9FMX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium TMED137|TrEMBL
MAILSSXRASRPXLSFEFFPPKNDLGSEELLETVNELGKLDPAFVSVTYGAGGXTRERTR
EVVQRIIQDTNVPTIPHLTCVGHTKSEISEILSQYSADQVGTILALRGDPPRDQPNYDXE
GDDFKFAGDLVXFVKENSNEFEVGVAGFPEGHPETQXRLTEMDYFKSKIDQGADYICTQL
FFDNXDFFDYRERCNLVGXDLPIVAGIMPITTISSMKRMADLAAGSRFPAKLLKRLSVAD
GDAAAIRQAGIDHAIEQCQELIEQNVSGXHLYTLNKSXATREIANALTF
>A0A4D7WX02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria subflava|TrEMBL
MNHAREINALNHSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVMMGIDVEIVPGILPVTNFKQLTKMAQVTNVKIPSWLSKMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRPR
>V4Q1M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asticcacaulis sp. AC460|TrEMBL
MEQTLWASIARLAPLEPGFVSVTYGAGGSTRERTHRTVKRILDETALKPAAHLTCVEASR
DEVDEVIREYWGAGVRHIVALRGDPPSGWGDYTPRPDGYQNATELTAAIKRIGDFEVSIG
VYPEKHPQSPSLDFDLDVLRAKVDAGATRGISQFFFEPETYLRYRDAVFDAGIDIELTPG
IMPVTNFKGLRRMAAACEAQVPDWLEELFAGLDDDAETRKLLASAVAVELCLELEREGVE
NFHFYTLNRADLVFAICRILGLKALAL
>A0A066ZZD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenovibrio marinus|TrEMBL
MNSQKKYPQKLSLEFFPPRTPAGVDKLKTVITELGGMAPEYMSVTYGAGGTTQEKTLETV
SYIQQHTPFDAAPHLTCIGATHESVLELLNTYEALGIKRIVALRGDLPSGMMDPGEFKYA
SDLIAFIKQEKGDTFHLEVAAYPETHPQARNCEVGIKWFKHKVEQGADSAITQYFYNVDS
YLYFIDNCERHGIDLPIIPGVMPITNYENLVRFSAGCGAEVPRWLKCRLESFEDDKESLL
AFGQDVVTEMCQRLLDAGAPGIHFYSMNQTQPTLDIAKSLTFKNA
>A0A1Q6GV39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. 43_46|TrEMBL
MKVIDLINNSKKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEEAPNIESDLYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAERVGIEWCVTQCKELMSHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A1Z9Y3U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Endolissoclinum sp. TMED26|TrEMBL
MNMMRQQIISAASGFSIETTPGSAAKVANFADHLAAGTTVNVTYLAGSDAAETIAVCQRL
RDEGMRPVPHVAARNIESAGQLDDYLGALTXEAGVDEALVIAGGLDRPAGPXDCTMQVLE
SGLFGKHGIRRIAVAGHPEGSPDIHDDALAAALADKNQWAKENAVDMYIETQFCFEAXVV
LAWERRIRAAGNRLPIHIGVPGPATLKTLLKFAQMSGIGPSMRVLTRQARNLSRLLMVQA
PDRLVADLAIAMAEDPACLIAGFHLYPFGGLAKTSAWINAVAAGQFDLQDGGRFTVTEPL
KTAL
>A0A328AUQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium hankyongense|TrEMBL
MTPSDTALGPIARAGVGGTARPNVSFEFSPPKTPEAEESLWEAIRRLEPLNPSFVSVTYG
AGGSTRDRTHRTVLRMMKETTLRPAAHLTCVEASREDVDEVIRDYWAAGIRHIVALRGDP
PGQIGGAYTPRADGYRNATELTAGIQAIAPFEVSVGLYPHIHPESPSIEHDIDVLKAKID
AGATRAITQFFFDIDGFLRFMDRVRKAGVTIPISPGIMPVTNYKGLKRMAGPIGISLPGW
LANLFDGLDKDPETRRLIAGSVATELCARLAEEGFADFHFYTLNRADLTYAICRVLGVRE
PTPEPKEAAA
>A0A084EH09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaesserella parasuis|TrEMBL
MSYAKEIDLLNQSVADLNGKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERNRTHSIVKTIQQETGIVAAPHLTGIDATPDELRAIAKDYWDSGIRHIVALRGDEP
TGYAKKPFMRRI
>G2ZP01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|blood disease bacterium R229|TrEMBL
MQDRQFRFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILNTYRENGIRRIVALRGDLPSGMGEIGEFRFANELVEF
IRHETNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLLRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>A0A381YZ97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MEEKIDLLAGHVHAINVTDNPGATAHMSSLAGCSIVRNKGIDPIFQVTCRDRNRLAIQSD
LMGASALGVNNVLTLAGDPVKNGDQPDAKAVFDINSKKILSIMQSMNDLGETMSGRELQT
KSNFFPGGAAIIHEPENNWNPVALKDKVDHGAKFIQTQFCYDVDLLREYMKHIVDSGLSE
KLFFIIGIGPLRSDKSAKWMRDKLFGTVIPDNIVQRMERSENQIEEGVAICAELINQFEE
IDGVHGAHLMAPRNLSAIAPTVKQAGIKI
>A0A382FFQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MMRSDEPSPVNLPLGHYSPGRLEQVLRAGDFAVTAEMAPPDASDAGEVYRRASVFDGWVD
AINATDGSGANCHMSSVGVCALLTRKGYATVMQISCRDRNRIAIQGDVLGAAAMGVTSVL
CLTGDGVEAGDQPDAKPVFDFDCMSLLQTVTTMRDRRELLSGRKLTEPPRVFIGAAANPF
APPLDYRPLRLKKKVEAGAQFVQTQYCFDINRLENYMQQVCDLGLNERCFVLVGVGPLVS
ARTAAWMRDNVPGVHIPDSIIKRLLGADNQKEEGTKICIEMIQRIREIDGVHGVHVMAYR
QEESVPEIINASGVLGGRSPWFPSAGGP
>A0A381Y210|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MSKNELNFSFEFFPPKNKAGEESFWETFKKLETFEPNFVSVTFGAGGGERDKTDKFVRKI
NERSDIPVAGHLTCVGMSKDEINNIAKGWLDVGVDKIVALRGDTRVPGEKYRPHPNGYIN
AADMIRGLKKIGNFEIVVAGYPEKHPDSESLVVDIENLKQKVDEGADKIITQFFFEKETF
LRFRDRALSAGIKIPIIPGIIPIDNYEKIYKFSKNCGATVPLWIEKEFKSCKNIPEYFNF
VSTKIISNLVHNLQSEGIKDFHLYTLNKINLSLIACTRLLYGDYSLKEMKEVYKN
>A0A7V9F332|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MRNSSRSDSAIKAALASARYEVLPTAKIEAAVLESVPTSVTLTVTASPAKGIESTLAMAE
RFAGHGYQVVPHLAARMISGKGELSEIVARLTAGGIDNVFCPAGDADPPAGEYGGSLAML
QHLTELGRPFEHVGITGYPESHPSIEDDITIQSMWDKRAHATYVVSNLCFDPDAIRVWLL
RMRKRGIELPVLIGLPGPVERAKLLAMSTKIGVGQSAKFLKSHVGAFARIAAPGGYSPEK
FLQKSAGYLGDPALKVDGLHLFTFNQVAETEAWRQDLLSRP
>F5X781|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pasteurianus (strain ATCC 43144 / JCM 5346 / CDC 1723-81)|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADIIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAREAAGDDAFVLGTVGALRGLKQCNLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEVELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKEANFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDGLADLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALEHFKGIYLITPFMRYDLTI
ELIDYIHQKVELKNQRIS
>A0A383B6R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MNISFEFFPARTEHGKKALNEVQKKLSAIKPEFFSVTFGALGSSQDATFETITDLLKNTN
VPIAPHLTCVGIKKIQATALLDKYIELGVNRVMVLKGDTPQVRFPYKNSRDKGDFHFA
>A0A1A5S3B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3873|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIQEFADFGVTRFVALRGDPAAGVGT
AYRPHPNGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A382GQ71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKVIEHIDNAKDPLFSFEIIPPIRGKSAQEIIDIVKDLEPFNPPFIDVTSHPAEAYYEEN
TDGEVKRRVRKKRPGTISICGIIQNRFKIDTVAHLLCRGFTREETEDAIIELNYLGIHNI
LAVRGDETNYKKPVQAGRTVNVFSSDLVKQLNDLRSGIYLDEIINADPVDLCIGVGGYPE
KHFEAPNLKKDIEYLKQKVDAGADYIVTQMFFNNAEFFHFVDECRKAGITVPIIPGLKIL
NNPKQLTSIPKNFYVNIPTELSEAIEKNPKHTREIGVEWCLKQCEELLESGIMCIHYYIM
SGASAVTKVLKELNK
>A0A7W0M2D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MARGLPSRMPGRAPAIRDLIAAGERSFSFEFFPPRDDEGEVRLWQTIRELEPLHPTFVSV
TYGAGGTTRERTIRITGRIAVETTLTPVAHLTCVSHSRDELRQVIGHYADAGVRNMLALR
GDPRGGPGQPWTSHPGGLDHAVELVQLVRRLGDFCVGVAAFPEKHPEAASPDSDAAVLAA
KARAGADFAVTQLFFDAEDYFALLGRVRALGCEIPIIPGIMPITNVAQVSRFAELSGSAV
PDRILDQLSPAKDAGEVRRIGVGLATALCDELLAGGAPGLHFYTLNRSKATREIFTALHV
TSP
>A0A520VA93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MIKKKFIKTIEIIPSRYKIDNLFLNKVLKYSKSFDFIDLACAPMANLRISPISFAHNLIM
KGIDPQKIIINISVRDKNSLALQSDILGASGMKIKNLLLVKGDPISIGNSKKSKEVFELN
TNDLISLVAKLNKGRDYSNNKMDYKPGFAIGSTLNIDLPIEKIKRNLRNREKIGSNFFIT
QPLYSETDFVNLCELSSISSSKILAGIFPIKNIRTLNNLNNKINGINKDNPLFKTLKKAD
EKDFQKLSSSYLVDLLIKYKKDLDGVHIMTAGDLKVASKLSEKI
>A0A3S0Q033|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium anhuiense|TrEMBL
MSPRAALIDGYSFEITGKDTAGLQDVSKLLAPATCVSIAFIPNENHDARLAAAATVKELG
FHPVPHISARRLGSAAELDRLLALFVSVANVDRLFIVAGDPDVPVGPYEDSLAIIRSGLL
SKHGIRKVGIAGYPEGHPKIRDGVLFEVLQEKHALLTAAGLEYDITTQFSFEAEPVIEWI
GRLRQAGITAPIRIGVPGPASVKTLLRFATICGVGASTKVMAKYGLSIRKLLNTAGPDAL
VAEFIRRLDPSKHGSVCLHFYPFGGVGKTAEWIRDFLASHISK
>A0A1Z9L628|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. TMED187|TrEMBL
MDSTALQHSLNAGQPTITAEVMPPRGGDVRHTLAMAAALRGRVHAVNVTDGSRAVMRMSS
LAVCRLLLDHGMEPVLQIACRDRNRIALQADLLGAHALGIRNLLCLTGDPVTAGDQPKVR
PVNELESVRLLHQVTAFNRGEDPVKGDLADGPTALFAGAAADPHCSSQSGLLRRLERKRE
AGARFLQTQMVMDGAVLERFCTDLAAPLELPVLAGVFLLKSARNAGFINRMVPGACIPDA
LIARLEAAEDPAAEGIAIAAEQVKRYMGIAQGVHLMAVRAEERIPLVLEQAGVSPVSV
>A0A2S7I357|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cloacibacterium normanense|TrEMBL
MKVTEHIQNANGKTLFSFEILPPLKGQNIQSIFDAIDPLMEFNPAFIDVTYHREEYEYVE
REDGLLEKRVVKKRPGTVGICAAIQNKYGVDAVPHILCGGFSKEDTENFLIDIDFLGIHN
VVALRGDAVKTETYFKPEKNGHAFAKDLVEQIVKMNHGTYLDESLENSACTDFNIGVAGY
PEKHMEAASLEQDIYHLKKKVEAGADYIVTQMFFDNQKYNDFVEKCRTSGINVPIIPGLK
PITTKSQLSMIPHRFKVDLPNELVIAIAKAKDNKEVKEIGINWCIQQSKDLMKNGAPVLH
YYSMGKSEVVKRIASEVFKD
>A0A2E9A0J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MKVXEHIXQSKNTRFSYEIIPPLRGKGIQVIIDMVKDLNKFNPPFIDVTSHSSSVSTYGD
GKQVLKRKRPGTISICGIIQNRFKIDTVAHLVCNGFTKEETEDALIELSFLGIQNILAIS
GDGNPKSKIDEGKTINPNSLNLVKQINDLSKGKYLGDIENSSSIDMCIGVGSYPENHSFS
NDFDKEIRLLKEKIDAGAEYAVTQMCFDNKKYFDFVDRCRKKGITIPIIPGIKILDKPKQ
LETLEKMFHITIPDELRNEALENIEYIDEIGTKWAIKQSEELINAGVPIIHYYLMNDTSC
MLKILNHLHQ
>A0A436KT80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.04.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A3P8KSM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella terrigena|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKKRPGGSAEPEA
>A0A523V0J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium|TrEMBL
MKLKDLFKKGKFVITSEIGPPKGTNIEPMLEEVDLLRNKADAINVTENQSSVMRLGSMAV
CRLLKERGFEPVFQITCRDRNRLALQSDLISASVLGIENVLCLTGDHVVLGDHPQTKSVF
DLDSIHLLKVARGLGNGYDMVGNKLDGVPDLCLGAVANPGADPLEPQIIKMEAKVEAGAE
FFQTQAVYEVKKFEDFIKAAEHIKVPIMVGIVLLKSAGMARFMNANVAGVFVPDKFIKIM
AEASKEDRPKRSIEIAASLIKEMKGMCQGVHIMSLGWDRYVPGLLEAAELA
>V7IUS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Cubana str. 76814|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A815I3B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adineta steineri|TrEMBL
MYNNEIDPDAGHHPHVFKRAESDSGLQAKGCCLQTVKYVSLTEKIEKRIASNDRWYSLEF
FPPRTPSGAANLIGCFDRMAVGQPLFCDITWHPAGDPASNKETSSMMIANTMLNYCGIDT
MLHITCYGAKKEHMLEYLYKAKEFGIRSLLALRGDPPVGGEWDPKKXKYVSLTEKIEKRI
ASNDRWYSLEFFPPRTPSGAANLIGCFDRMAVGQPLFCDITWHPAGDPASNKETSSMMIA
NTMLNYCGIDTMLHITCYGAKKEHMLEYLYKAKEFGIRSLLALRGDPPVGEKWDPKKSDF
RYGVDLVKFIRQHFGDYFVICVAGYPQGHPDSTSYEDDLGYLKEKIDCGADFIITQLFFK
PETFIKFESDCRAIGITCPIIPGIFPIQGYASLRNIVRLAKLDVPKEILACIEPIKENDE
AIRNFGVQTCLDLCSALLDTGKVHGLHFYTLNREFATIEVLKKLGLWLEEHPLRALPWKK
TSNSHTRSKENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGMLTDYHLFYMKI
DATRDELLDEWGRELTCEEDVWRMFACYIGGEKNTSNKVVRHFPWTDEELSLETTLIQNN
LIEFNRRGILTINSQPAVNGKPSSDPIVGWGTSNGYVYQKAYLEFFTSADNIPALRDVLK
NFPSVNYHFVNKSGESNETNTVDEQPIAVTWGVFTGREIVQPTVVDPVSFMIWKDEAFSL
WTERWGKLYEPESRSHAIIEQIANTYFLVNLVDNDYVEGSCLWTILDSMFEYQKVSKTNG
NI
>A0A2I1YHL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus macedonicus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADIIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAREAAGDDAFVLGTVGALRGLKQCDLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEVELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKSLDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKEANFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDGLADLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALEHFKGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A482RML5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon|TrEMBL
VTAALRPAFISVASRVGAKEWQSTVAFAADIQSTCGVDVLLHVTCHLTPAVLRALLEDAK
AKGIRNLFACRGDAPHASSSVAWRPPPGGFEHAVDLVRLIRKEHGDYFCIAVAAYPEVHL
ECYNNPRLPPSNQARARDMAHLVDKVAAGADFVIAQFVYDPNLFLSFAEAARTAGVLVPI
VPAYMPIQVRSRAPQHVCACVRVCARVCTCVGMLCVAALCASLRGCGLQTYDSFQKVTSW
CRTRVPPRVTADLARVREDDAQVKAYGVTLGAATLDAWFTAGCKSVHLHTMNMFLSVAHI
LVAARVRSPVCLTELSLAHGGVGTSDALRGTASATGAGSASALVGDWTEFPNGRFSAVSS
PAYGELTDYYLSSKRPKVDRRALWGVPSSIADIKRVFIMFLDGVISALPWYEATPAQETL
SIYESLRWMNQCGFLTINSQPRVNGAPSSDPRFGWGGVDGVVYQKAYVEFFVAPHQFRLL
LQALPRYPTLSYHALNAAGEEYVNVAVDKANAVTWGVFPGREIIQPTVVDPKSFRIWKDE
AFDIWKTQWQSVYNEDTVRTALRAACVRARAWLRAHLRTLRCAWGHALCCRRRSAPRGAC
CKRCTTRTSWSSLWTTTTCPSPA
>A0A3E1DRK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrotoga sp. CP45|TrEMBL
MTNSKSFSFEFFPPQTQEGANKLASARRQLAVLKPAFFSVTFGAGGSTRERTLEAVQQIK
ADGYEAAPHLSCVGSTRENIRTILHTYKNMGIKRIVALRGDLPSGMATSGEFHYANELVS
FIRAETGEHFHIEVAAYPEFHPQAKSPRDDLLNFKRKVMAGANSAITQYFYNADGYFRFV
EECRKLGVTLPIVPGIMPIMKFSQLARFSDLCGAEIPRSIRKMLESYGDDNESVQAFGLD
VVTQLCERLLVGGAPGLHFYTLNQSAPSMEIWKRLGL
>A0A1C3WKD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium hainanense|TrEMBL
MKQNVEIAEVSIGGTEALPHTALFNNFSIEITGKDTAALQGASHLLAPATSVSIAFTPGE
SHDARVAAAVAARRLGFRPVPHISARRIVSAAELDALLARFVREAAVNSLFVVAGDPDLP
LGPYGDSLAVIRSGLLSKYGIRKIGIAGYPEGHPKINSPMLFDALREKHDLLTDAGLEYD
ITTQFSFDAEPVIGWIERIRRMGITAPIRIGVPGPASVKTLLRFATICGVGASVKVMAKY
GLSIGKLLNTAGPDVFVDELTRRLAPAEFGTVRLHFYPFGGVGKTAEWIRDFPSNRK
>A0A3T0S374|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidipropionibacterium jensenii|TrEMBL
MQPTRTSTATIADLLARPGRPLRSFEFMPPRSEEDVYRLWQATDSLVPLEPDFISVTYGA
NGSNRDRTLRCTRHMVASGLRTVGHLTCVSQSVAELEQAVCDYRDAGVDHILAIRGDMPG
GATEPWLARPDGLANATELVRLVKRVNPQACVGVGAFPDGHPASGDLDLDARILADKARA
GASFAITQLFFIPEHYTRLVARVRALGCDIPIIPGIMPITSYGQIRRFGDLSGTDVPADL
VARLTRVADDRAAVREIGLEAAAQLCCRLLDEGAPGLHYYTLNRSRATTELHSMVRDRRP
QLWDR
>F3ZSM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides coprosuis DSM 18011|TrEMBL
MKVTEHIKYSNNKPSFSVEILPPLKGENIQDIFKALEPLMEIKPTFVDVTYHREEYEYKE
TKEGLWEKRIIRKRPGTVGICAALQNRFGVDAVPHVLCGGFTKEETENLLIDLHFLGIDN
IVALRGDAVKSEIYFKPKKQGHRYANELVRQIDNQNQGIYLDNELLNTTKTNFCIGVAGY
PEKHIESPNMDADIQFLKQKIDSGASYIITQLFYDNQKFYDFVEKCRAAGITTPIIPGIK
PLSTKRQLNLIPYRFNVDIPIDLANDVIKAKTKEDVIEIGIEWMIEQSKDLYSKGFNLIH
FYTMGKTDPICRLAKTIL
>V6AU75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosotenuis uzonensis|TrEMBL
MTIRYEINPPRVIEDKVLSHKEVQASLKRIQKRISKISNLCDGIHLTDSVLGVPRISPIT
TGAIIRNDGIKMDITASLRVRDRNITALTQSVYDAILLGLDGLLILKGDEPPKGPKDSKL
VPSDIVRHFKDLGFGKNLDFFLSIPADPDFDKITKKISAEPTGFVTQVIQSKDQVFRIVD
RLKPQGFKIIPCIMIPSENNTRSARMLGIEFSRYEESILDFIVEIYKLTKDVLITSPNDF
AAATKVLAGIKGLKRK
>A0A7X8K655|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierellia bacterium|TrEMBL
MKITELFKRGEFPVTAEVGPPKGFHIEHLLEEAKTYLKDITAVNVTDNQSSVMRLGSLAT
CKALKDEGLTPIFQLTCRDRNRLALQSDLLSAAMFGIENLLLLTGDHTTLGDHPQSKPVF
DLDSVSLLHTVKTLEQGSDLAGNPLDGPPPSFAKGAVVSACSDSVDVQLAKMELKIKAGA
EYFQTQAVFEPEKFIQFMEKAKQFGVPVMLGVIIPKSVGMVKFMNDNIAGINVPDPLIDE
LRADKEKTKAGITGVEIAARIIRECRPYCQGVHIMALGWESKVPDLLAQAGI
>A0A7X8FRF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierellia bacterium|TrEMBL
MKVHEQSALPSYSFEVFPPKRDGDKKQIYETLEAIAVHNPDFISVTFGAAGSDCGKETLD
MCTHIKDNLGIRPLMHLTCVGADTQSISHTFDAMEEKGISSTLLMRGDKKEGASDAEQFS
DFRYAKDLIDYAVKNRDFSIGAACYPEGHIESSSLTQDLMHLRDKVKSGVDFLITQFFFD
NDKFYHFKEQARSIDIDVPIYAGIMPVLNKSQIKKMVALSGASLPPKFVRILDNYEFNPE
ALQDAGIAYASEQIIDLLSSGVDGIHLYVMNKPEVARRVTENIASIVKELKERPKIA
>A0A8B2W4A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. dmp5|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FILLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1Q7R799|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium 13_1_40CM_3_65_7|TrEMBL
MKSHPFLARLEQGVLLADGAMGTLLYARGVAFDQCFDELNLSRPEVVRQIHLDYIASGAE
LIETNTFGANRFKLGQHNLAHRVAEISHAGAALAREAAGTANRHVFVAGSMGPIGRPMAP
LGAITPEDVRSAYAEQATALVEGGADVLILETFTDLNELLEAVRGVQSATAVPLIAQMTF
TQDGKTMLGHEPREIVRALEQMDVDVIGANCSVGSQGILEVLQQMAAGVTRARLSAMPNA
GFPAYVGGRYIYFSNPAYMAGYAAQLAAVGVRVIGGCCGTTPEHIAAMRRALAEPVERAV
DLTIPADLRSSRPAESEPVARPQDPTPFAQKLGRSFVITVEIDPPRGVHDRRELDGCRRL
NDAGVDVIDVADNPMARLRMSPWAMCARIQAEVGVETVLHFTTRDRNLVRLQSDLLAVHA
LGIRNVLVLRGDPPQMGDYPNATAVSDVKPSGLVRLIKKFNQGHDVAGNAIGTPTGFTVG
VALNLAAPDLDKEARILERKVAAGADFICTMPIYEPEALDRFERIMGGLPVPALLGVLPL
VSHRHAEFLHNELPGFAIPAWVRERMHQATDARQEGIRVAVQLMEAVRLRVGGVYLVPSF
GRYDGVLELVRLARQPAKT
>A0A2H9PGZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeum sp. CG_4_10_14_0_8_um_filter_32_851|TrEMBL
MYKITDIFKRKKKTFSFEFFPPKTEEGMKHLFETCDELKKYPDFFSVTYNPDGSSRERTL
FVVNEIQKKFKIPVMHHLTCINYNERTL
>A0A850F681|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium BIT-l23|TrEMBL
MSFFHANQREALNQSLAELHGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDASRDELRTIARDYWENGIRHIVALRGD
LPEGSGRPEMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNYKQLQKFATMTNVRVPKWMDSMFD
GLDNDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAA
>A0A7C7Q1Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MSRLQESLERREFVVTGEIGPPKGVDIESTLEEASHLRGRVVAINVTDNQSSVMRIGSLG
VCIRLLQEGYEPIFQVTCRDRNRLALQSDILSAYILGVRNILTLTGDHPTLGDHPQSKPV
FDLDSVSLLMAITSLMEGKDLAGKELDGRPSDLFPGATVTPGADPPEPQLIKMEKKIEAG
AKFFQTQAIYDPEVFEKFMNHASRFGVPILAGIVLIKSPAMARYMNENVPGVFVPDSIVK
PLSEVSRKDRAKKSIELMAGLIRELKPMCQGVHIMAMGWERYVPELLNACGL
>A0A7W1A550|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
MGTMLYTKGVFINQCYDELVLRAPDLIRDVHKAYRKAGAEVLETNTFGANRLKLSQYGLE
GQVAAINRGAAQLAREVAEDDLLVAGAVGPLGVRLEPLGPTSIEEARSIFREQMTALKEG
GADVFLLETFGDLHEIEQAILAARDVDPSTPVIAQMTIGSDCHTPYGVTAEDLARSLDAF
GADVIGLNCSVGPQIILDAIEKMAPLTRRKLSAQPNAGMPRDVSGRSMYMASPEYMATYA
HHLVQAGAKIVGGCCGTTPEHIAAMVEGVRPLSPRQARVPMRDRRNTHPDVPAENPGVTP
LPFAERSKWAGKIARGEFVTSVEIVPPRGVDASKMLRDTVALRDAGVDAVNVPDGPRAQS
RMGALLTGLLIEQQSGIETVIHYCCRDRNLLGMLSDLLGAAAIGLRNMLLITGDPPKMGP
YPNATAVFDIDAIGLTNLVRNLNRGLDPGGNAIGAPTSFAIGVGVNPAALDPAQELKRFE
WKVEAGAEYAITQPVFDAAQLERFLGTIEHTRIPIVAGIWPLVSLRNAEFLANEVPGVVV
PPAVIDRMRIASAHSKEQGVAEGVAIAREMLERVRPLVQGVQVSAPFGKVELALDVFRDS
LTPAVSRTS
>W8X8E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Castellaniella defragrans 65Phen|TrEMBL
MNGSASAISLEFFPPRDIAAQERLVRSAKRLEALRPAYVSVTFGAGGSTRTGTADTVRML
QNLGVDVAPHLSCIGATRAELRAILDDYRARDIRRLVALRGDLPSGMGGDTGELHHAADL
VRFVREHYGDHFHIEVAAYPEMHPQAESAAADLRHFVDKVRAGADGAITQYFFNPDAYFD
FVDRVRAQGLDIPVTPGIMPVTNYTQLARFSSMCGAEIPRWMRLRLQDFGDDKASIRAFG
IEVITRLTARLLEQGAPGAHFYTLNNADAVAQICANLGLDA
>A0A562RFF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobotulus alkaliphilus|TrEMBL
MLLSDIFEKNPMTFSFEFFPPATEKGWESLFHTIADLMPLEPAYVSVTYGAGGSTRDRTH
RLLARIHRETPLTAVSHLTCVGASRDEIHDILGAYDALGVHNILALRGDPPAGEPFTPHP
DGFLYAADLVAYIKKHFPGMCVGVAGFPEGHPATPNRLLEIDYLKAKVDAGADYIVTQLF
FDNRDFYDFQDRCQLAGIDVPILAGIMPVTTRKGMERMAELAAGARIPAPLLRAVHRAGS
DAMVENVGVHWATEQVRDLIDHGVRGIHFYTLNRSPATLRIYEALGVKNSRNLSR
>A0A4P5X7Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetia bacterium|TrEMBL
MSLKNAYTTGPLALSFELFPPKTPESEGVMWGTVADLMAFQPALVTCTYGAGGSTRDKTL
DVIEGVRRRHDVPVASHLTCVGSTVDELRAYLHEARERGTAAIVALRGDPPKGETTFQPV
AGGLRYAAELVALIRGEFPEFAILVAGYPETHQEATSPVADLENLKRKCDAGADVVVTQL
FYDNEDFFRFRDQCQAHGIGQPIVPGVMPVTNYAQIRRIASLCKARLPDTFTRAFDAAGD
DEAAQFEAGVEFAARQVEELAAAGVPGMHFYVLNKSPATIRVLDAAGLAAGARRG
>A0A2G4H6S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilia bacterium|TrEMBL
MNATDNTAAHAHASNVAMAIAMQRVGVEPILQVVCRDKNRIAQQADIMGAALHGVENICC
LTGDDVTAGDEPEARRVFDLDGPQLVRLANSLKEGRYLSGRKIDPAPSLVIGAVENPATH
PLDYRAQRAAKKILAGARFLQLQICYHPERLEAFVAALHLNGFTDKCAILPTVVAVKGPG
PLRFMDSSVPGISVPTETIARVADADDSAEEAYQLVLEQCQHALALPGVRGLHLTDFRKD
GSMSRLCTDLGIRPRSDRESRANDFALAN
>A0A2R7NEM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. HMWF017|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A2N2HFA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-20|TrEMBL
VYDLRSLELMALLAGFNEGRNHYGDSMRLPVNFCIGGAFNPNTRSMALQVGRMEKKMAAG
ASYFLTQPVYSKERVDEILAATAHITAPIVLGIMPLASSRNAEFLHNEFPGIEIPSETRE
RMARAGEHGQEEGVNIAWELLEYAWPHFAGVYIIPPFNRHAMALELMRRLGR
>A0A8G2C765|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halodesulfovibrio aestuarii|TrEMBL
MKIIDAIKSQSKPFYSLEFFPPKEKKQWDSFFSTVERLKALNPLFASVTYGAGGSTQDNT
LEITSRMKHEAGIEPMAHLTCVGASKEKINGFINKLREADVHNVLALRGDRPADEKFSWT
DQQLRYASDLVGLVSNEHPDFGISVAGYPAAHPESPTFADDLHYTRVKIDAGSDFVVTQL
FFDVREYFDFVSRLRSNGINKPVIPGILPIQSLSSIRRILSLCGANIPGQLYLSLEEANE
KGGDDAVKETGLKFAVNQIRQLVDGGAPGIHLYTLNKADMCLELADRVKL
>A0A7X7RD73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MKISSLFEQGRPLYSFEIFPPKRTAPVETIYHTLEQLDGLHPDFISVTFGAAGIITDKHN
PLEIATMIKERCHTEAMMHLTCINSSRADIDEISADAQQRGIENILVLRGDRMPDIAPRT
DFRYAEDLAAYLSRRGGFCLSGACYPEGHLDSPDLQSDIGYLRRKVDAGCSHLVSQLFFD
NRFFYDFLDRARGAGIAVPISAGIMPVTSKSQIEKMITLCGASLPNKFAKMMQRYEHYPQ
ALMDAGVAYAIDQIIDLVAQGVDGVHLYTMNNPGLARRITDSVSSLFKAGK
>A0A662GGL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoprotei archaeon|TrEMBL
MKAVLKTNSRLEKILESGKFAVTAEIGPPKSADAEVIKRKARALKGYIDAFNVTDGQTAV
VRMASWAACLIGKEEGLDPIVQMTCRDRNRIALQMDILGIAALGINNILCLTGDYVSMGN
HPSAKPVYDLDSIQLIKTVK
>I2MWW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces tsukubensis (strain DSM 42081 / NBRC 108919 / NRRL 18488 / 9993)|TrEMBL
MALGTASTRTDRARTVREVLATGQTSHSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVRATEQIASDTTLTPVAHLTAVNHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVRHPDGVTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVD
KCRAGADYAITQMFFRPADYLTLRDRVTAADCDTPIIPEIMPITSVGQLERFAQLSNAAV
PSELKERILAVKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYENLG
LHEQV
>A0A6G9W4S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. AK26|TrEMBL
MSRPQISFEFFPPKTLDASFRLWETARALAPLAPDFVSVTYGAGGTTRKLTHEAVTTIHR
HYGIPVAAHLTCVEATRAETMEIVQAYADAGIREIVALRGDAPKGQDRFTPHPEGFANTV
ELIEAIAARGDMTIRVGAYPEPHPDSSGTDADVAWLKRKVDAGATSAITQFFFDADTFFR
FRDKCAAAGIDAPIIPGILPIQGWAGAKRFAATCGTSVPAWAEEAFSKAAAQGPAAERAL
SEQACVKLCRDLLEGGVDRLHFYTLNRPDLTLAVCGALGVEPLRDLGAVA
>A0A7X1ZV51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MKVVNLYKGNKPVFSLEVFPPRNGESLEAVLNTIDSLWSFKPAFVSVTGGALGSMRGGTI
AIAAGIKRKYGVEGIPHFTCVNKSKQDIENLLMEMKFNEIENIFALRGDPPMGQKEFIPH
PEGHKYASELVEQIKLLNEGVYILSSVEKDYKVSPTNFGIAVAGYPNGHPECPDKKKDLE
HLKIKVDNGADYIVTQLFFDIDVFLEFVENAKRIGIDIPIVPGVMPLDKYGQIKFISKQM
GIEIPEKLKDKLEAHKDDKDAIKKILEEHTLLMCKKLVEQGSPGIQFFTMDKPEGTKKVL
QELCKEQKMTFVPRV
>A0A7X1ZKW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MKAGSNLEKVLQSGQFAVTAELGPPKGSDAEMVKKKGNLLRHCADAINITDNQTAIARMS
SIACGVILTQLNLEPVIQMVCRDRNRLAIQSDILGAAALGIKNVLCLSGDHQKFGNHPQA
KNVYDIDVIHLIQTLKKMRDEKKLLEGDELTIEPRLYIGAVENPYADPYEFRVIRLAKKI
KAGCDFVQTQGVFDVKKFKDWMRVITDQ
>A0A4Z0NSR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium nonmethylotrophicum|TrEMBL
MYATAFRPSRESRRPIRVSFEFFPPKTPEMEATLWSSIERLAPLGPSFVSVTYGAGGSTR
ERTHNTVARLVRETALKPAAHLTCVAATKGEVDDVVRAYHEAGVRHIVALRGDPAEGVGT
AYTAHPGGYERSCDLVAGIKRVGDFEVSVSAYPERHPEAGSLDQDLDALKAKVDCGADRA
ITQFFFDNDLFFRYLDRVQARGIAIPIIPGILPVQNFKQAANFARRTGSSVPDWLAARFE
GLDDDVATRKLVAAAVAAEQVLDLVDRGITDFHFYTMNRADLVYAICHLLGLRAAPGAVE
KAAA
>A0A537B9P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MQADLTVEPETALGALKDDERRNIPALLAGASLELSSRDPAEIDACADLLEPGTAVYISM
PPGQTYHGNVALATRLRRAGFRPVPHVAARRIASRDALEEYLARAAGEAGVDSALVIAGD
SDRSSGPFDSSRALLETGLFQRHGVVRIGVAGYPEGHPKITESALESALTAKKVLAREAD
LDLQIVTQFCFESAPILAWAAKMKGHGLPMHIGLSGAASLPRLLRFAALCGIGNSVRALK
ARPRAITRLLVEAGPEVVVRDLARPGRAAIAGVHFFCFGGLLRTARWLRGVREGRFELTP
DGGFRVEAA
>A0A1Q5ACA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB00072|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVRA
TQQIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A8SW94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus eutactus ATCC 27759|TrEMBL
MKIRDLITQDKATLSFEVFPPKKDTDFADVEAAALGIAALKPDYMSVTYGAGGSTKGHTI
QLAREIQEKYDVPTIAHLTCVCASRDGIKNALVEMKSAGIENILALRGDIPKNYDGQVFT
EFSHASELVELIKESGDFCVGGACYPEVHPDSANKHDDIAGLKKKVDAGCDYLTTQMFFD
NNIFFNFMYRVREAGINVPIIPGIMPITKRVQVGNAVKLSGCNVPERFKSIVDAFGDTEA
AMRQAGIAYATDQIIDLMANGVKHIHVYSMNKPEVAAGIQKNLSEILKV
>A0A0Q6URL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. Root343|TrEMBL
MTLPPTHRVIGPVARAGERGQSQAGGRPRVSFEFFPPKTPQMEENLWQAITRLAPLDPAF
VSVTYGAGGSTRERTHRTVKRILDETRLKPAAHLTCVGASRDEVDEVIREYWETGVRHIV
SLRGDPPPGEGGIGGVYVPRADGYANATELTRAVRGVAPFEVLVGVYPEKHPESPSIAHD
IDVLRQKVEAGATLGISQFFFDLDAFLRYVDKVRAAGITIPIVPGIMPVTNFNGLKKMAA
ACGTAIPSWLANLFDGLEDDAETRRLIACSVAAEMCAKLQEQGFEDFHFYTLNRADLVYA
ICRVLGVRETVPATAEAAA
>A0A0C2ZX59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuricurvum sp. PC08-66|TrEMBL
MFETLINKLHYGNYLTLETTPGHEPTMNTLMEKIETLGLHTKVDGFSTTDNPLAKLKYNA
LFAAMQLQNRFGLPVLATMSMRDRNKLALQSDLLGANDVDVRAILALTGDSAKISNQPNT
KGVFEADSTLLLEIIRCFNTGIDYAGKPLASAPKPIYPFSVVNSFAKNEKLLLKKMVKKI
SHGAIGIITQPIFDIENAKNMLSLHAQASMDASQKSTLILGLFPITKLRTAQFLSAHVPG
IHVPAIWIEKLTTASKISAQEEYKVGFEMSQKLLHDVIKLHPKVHLMTANQFGLAADLLA
>A0A2V2FP49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MLIRELLQSKPLTFSCELFPPKAGADLARADEVVEQTARLAPDFISVTYGASGNTSHNTL
RMARHIEEQNCTALAHLTCVSATRADIGVRLDAMLESGVQNVLALRGDLPEGETRPQDAC
FQHADALVREIRTHGGFCVGGACYPEGHVESASQEEDIAYLKQKVEAGCDFLTTQMFFDN
NVLYRFLYKLYAKGIAIPVLAGIMPVTNKKQIARIVRLSGTSLPPRFQNILDRFGGDSAS
MEEAGIAYATEQIIDLVANGVRGVHLYTMNRPDIAGRIMANLCHILGKTE
>A0A433VWS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroococcidiopsis cubana SAG 39.79|TrEMBL
MTEQYITDRDSRNSFRTAVKSGKFLITAEVTPPKGSDPTRMIEVALALRNWVHAVNVTDG
SRAVLRMSPLAAATILSQHGIEPICQMTCRDRNLIAIQADLMGANALGINNILALTGDPV
KAGDHAQARSVFDLEAVRLLQTITKLNQGFDYNGKGLCDGATQIFPGAAVDPQLASWSGL
QRRFERKVAAGAQFFQSQMIVDFSRLEKFMSQIAVKFNKPILAGIFLLKSAKNAQFINQY
VPGVNIPQAIIARLEQATDPLHEGIVIAAEQVRLARQVCQGVHIMAVKREDLIPQILEMA
EISPQGQSVQNVATTRIALAEPLLRRNSHNTNNFHTRL
>A0A537C519|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MDLATKEQSSSSAISELQRRLQDGSFVVTAELSPPVSTDPAEFIDHALALRGLVTAINVT
DGAGSKAHMSSLAAAHFLVRSGVEPVLQITCRDRNRIALQAELLGAAALGIRNILALRGD
DPTLGDQPDTKPVFDLDTTALLATAQRMRSEHRLPSGTEIKGAVRFVLGAAELPVDPSAG
WRPNGLLSKMAAGAEFIQTQFCMDGDAVRRYAARLLDLGVAQKLPILIGVAPIPSARSAR
WMKEKLFGAMIPDRIVDRLERAADPKAEGRRICVELLQQLVETPGVAGAHVMAPAFHSAI
GPVIEASRVAGTKRAGARRG
>H3F1N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pristionchus pacificus|TrEMBL
MTQIEIDCVARNASSASLSPYCGQPSPALANGGASSGDLKKCRLSETALSRPLSRTGSDS
DEFLKFEVPSQVGAQCSYRPLHERIEKRVKAGTPFFSLEFFPPKTANGVANFYTRLDRYK
EGDPLFVDITWHYGGDPANLTRETSSSSIAAGCLDYCRMDTMLHMTCTQYTKEQTIAHLE
QSKRIGLRNILALRGDLPPNTSSDAPVIKPKYMALDMIKWIKEEFGDYFTIACSGYPLGH
PEAVSYAEDLKYLKAKVDAGAQLIVTQLFFEAEAYERFVRDCREMGITVPILPGIMPIQS
YDSIRRIAQLSQLAIPDSILADLEPIKHDDDAVRNYGRHRAIEMCRRILSNGTAPAIHMY
TMNREGSCREILQELGLWHKRPMRALPWEPHGVNHPLRCKEDVRPIFWSARPKSYIYRTR
DWDDFPNGRWGNSSSPAFNDLHDYYLFNLHSTVNEKDKLRDMFGHELRSIDDVGRVFARY
IDQQDNEHGVKVTTLPWNEQENGVQAETSLISDDLVWCNERGVLTLNSQPSVNGAPSTDP
LVGWGKPGGYCYQKAYLECFISAENAASLLEFIDEHHPRINYHIVNKDGSMDRSNAEATT
PIAVTWGVFPGAEIAQPTVVDPISFRVWRDEAYDMWMKNWAYLYPADSRSHQVIEEIHNS
FCLLTLVDNDFVHPSILFDVVREMVARTETRTASSSPKEAVAQAIKA
>A0A537A4M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MEKLRATWKQLAQLKPRFFSCTYGAGGSTRDRTLETVLEIQAAGHRAAPHISCIGATRAD
IAATLELYKSKGIGHIVALRGDLPSGAASAGELRYASDLVAFVRERTGDHFHIEVACYPE
FHPQARSPREDLASFKRKIEAGADAAITQYFYNIDSYFRFVDDCEALGIDLPIVPGIMPI
GNFSQLARFSDACGAEIPRWLRLKMQSLGDDVASIRSLGLDVVTGLCDRLLSAGAPGLHF
YTMNQAGLTSTIWQRLGI
>A0A2V2CKZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MNENVPGIDVPQDMIDRLTAAAAEGKEKGIKGLPMQLGIEMAAEMIARIHDEHLCDGVHI
MAIGAEKNVPTILDKAGIRI
>A0A1H4CHS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium gillisiae|TrEMBL
MKVTEHIAAAKGKTLFSFEIIPPQKGKGIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYTVDTVPHVLCGGFTKEETEYLLVDCHYLGINN
VMALRGDAMKDEQSFVAKDGGNNFAVDLVQQIKLLNEGKYLHDVMHVDNKADFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PLAVQRHLQILPQIFRIDLPEDLIDAVDKCKTNADVKLVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A674MTU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Takifugu rubripes|TrEMBL
HFGGLSSQGGPGSCGASNSSGESSKESSRCSTPVLDADRSDRLRDKMRRRIESGDHWFSL
EFFPPRTASGAVNLISRWSERKGKLLVNVNKADEDDVAFCRFDRMGSGGPLFIDITWHPA
GDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQTKDKITGYLGKAKHLGLKNIMALRG
DPVGADWEEEEGGFNYAVDLVKHIRSEFDDYFDICVAGYPTGHPEAESYQQDLRHLKEKV
DAGADFVITQLFFRAETFLKFLDDCRTIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPE
EITSILEPIKDNDAAIRNYGIQLAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGL
WTEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFG
ELNDYYLFYLKSKSSKEALLQMWGEELLSEESVFEVFTFYITAQSNRCGQKVLCLPWNDE
PLAQETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTS
SENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVDPV
SFMSWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWQVIDD
MFELLDSPAAPPCEDATP
>A0A7Y3QXW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 3-2(1)|TrEMBL
MGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSAQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASRDELVQIADDYWHNGIQNIVALRGD
IPADGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQSDLVNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFN
GIDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A5Q0M0Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax paradoxus|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYVRKPQFCSVTYGAGGSTHQGTFGAVQEILAE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCACLQEGGAPAIHFYTMNQSAATLAILERLD
>A0A2E4LLS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp. SAT1300|TrEMBL
MKTALQCAIAAGKQVLTAEVMPPRGADPSHMLAMAAHLQGRVHALNVTDGSRAVMRMSSV
AACKLLIEAGAEPVLQLACRDRNRIALQADLLGAHALGIRNLLCLTGDPVRSGDQPLVRP
VNELESVKLLQQVEAFNQGEDPVKGSLPDGATALFAGCAADPHSRSWSGLQRRLQRKAGA
GARFVQTQMVMDPQVLDRFQRELAGPLQLPVLAGVFLLKSAKNALFINRVVPGACIPDHL
IERLENASNPAREGVAIAAEQVQRYLGIVQGVHLMAIKAEERIPLILDQANISSLTT
>A0A258RGF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. 28-62-11|TrEMBL
MTITINQLEEARRALDAPLFADLAGDANVSFEFFPPKTEKMEEALWETVKTLAPFGPRFV
SVTYGAGGTTRERTHATVARIQRETPMPAAAHLTCVEASRDEIDAIADAYWQAGVRHIVA
LRGDAPGSSGFVPHPEGYTNAADLVAGLKRLHPFEISVAAYPECHPDSRDEADDLDNLKR
KLDAGATRGITQFFFEPETFFRFRDRVSVAGIDAEMVPGIMPVTNFASILKMSAMCGTDV
PAWLGRLFEGLDDHPTSRQLIAATLAAELCRKLYAGGVRDLHFYTLNRAELSFAICHLLG
LRAKAAPLVAVNAAA
>A0A0P9PL65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. dendropanacis|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVKKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A4Q2RJP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lichenibacterium ramalinae|TrEMBL
MTAPDTLRPSRLPGAPIRVSFEFFPPKSAEAEAALWRSIERLAPLDPDFVSVTYGAGGST
RERTHNTVARLVRETRLKPAAHLTCVGATRREIDDVVRGYRDAGVRHVVALRGDPAGGPG
TAYEAHPGGYDSSADLVRGIRALGDFEVSVSAYPEKHPESSSFDADIDGLAAKVDAGATR
AITQFFFDNSLYARYVERVRARGIDIPIIPGIAVIQNFKQTANFARKTGASVPDWLADRF
AGLESDPATHQLVAAGVAAEQVLDLVDQGVRDFHFYTMNRAELVYAICRLLGLKPEGERA
AAA
>A0A4V3RQI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides distasonis|TrEMBL
MKVIDLIRNSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDTKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRTDIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A370MWK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus lacunae|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVKAGADSAITQYFYNADAYFRFVD
DVRALGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLEGFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A1H3H4F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetomicrobium thermoterrenum DSM 13490|TrEMBL
MKIKDIFERNKFVFSFEIFPPKPTTPLDRIYSTLDDLKGLSPDFISVTYGAGGSTRDRSP
QIAIDVKNVYDIESLAHLTCIGSTRDEVVGVVDLLLESGVHNILALRGDPPQEAVSPFVG
GDFSHAIDLVKFLRERYGEKIAIGGAAYPEGHIECDDPIKDLHYLKQKVDAGVDFLVTQL
FFDNELFYRFVERTSIAGIEVPISAGIMPVVNKNQIERIVTLCGASLPKKFVRILHRYAD
DPRSLEEAGIAYATDQIVDLIASGVRGIHLYTMNKAHVARKITSNIETLREGFVNDKNNE
EALL
>A0A1Q5MG97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02488|TrEMBL
MTMLRETLDRRAPSFSFEFFPARTPAGMRALWQAIRQVERLAPDFVSVTYGAGGSSRERT
IEVTKRIVAETTMRPVAHLTAVGHSVAQLRHIIGQYADAGVRDVLVVRGDPPGDPNAPWI
PHPDGFRYAHELVSLVRELGDFSIGVAAFPERHPRSPDWESDIRHFVAKCRAGADYALTQ
MFFQVEDYLRLRDRVAAAGCDIPVIPEIMPATDARQISRFAELSGAAFPEDLAHQLNAAR
EDPALGYRIGVEYATAMAERLLAEGAPGLHYITLNRSTAALEIHRAVTGSRSVRPAEMLH
G
>A0A562PKY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium glaciei|TrEMBL
MKVTQHIEDAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLEINN
VMALRGDAMKEEQSFVAKAGGNSYAVDLVQQIKLMNEGKYLHDVIHVDNKADFCIGVAGY
PEKHLESPSLLSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PLAVQRHLQILPQIFRIDLPEDLIDAVDKCKTNADVKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A3Q7Y949|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ursus arctos horribilis|TrEMBL
MDHPTPKVLPARPRGPSLGMWALEAGRVRFSVPPSISRNRAMVNEPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERHDRLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQITG
YLQKARRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFQFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQQLLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFAHYLS
GEPNQQGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLENCLWQVVEDTFELLNQPAPEGETEAL
>A0A844UB73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myroides sp. LoEW2-1|TrEMBL
MKVTEHIQKANGKTQFSFEILPPLKGQNIQGIFDSIEPLMEFDPPFIDVTYHREEYEYKE
AGNGLWEKRVVRKRPGTVGICSAIQHRFKLDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKNETYFKPEPKGNKYASELVTQISELNQGIYLDPELENTSKTDFCIGVAGY
PEKHMEAPNFDTDLKYLKQKIDNGAEYIVTQMFFDNSKFFAFVEKCRAIGIDVPIIPGLK
PLATLSQLNLLPQRFKVDLPDDLVAEVLKAKDNAAIREIGIEWCAQQSRELIDAGIPIVH
YYSMGKSDNIKKIIKLATV
>A0A7X7VJE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MQFIRDIYANGRTAGRPVFSFEFFPPKTDEGDRILFEKTLPALLQARPDYCSVTYGAGGS
TRDKTLRIVERIQRQHALTTVAHLTCVCATREQIGELLAQLRALGIRNLLALRGDPPGGG
EFQPAPGGFEFARQLVQFIRAQGDFSIGVAGFPEGHTACRAGRHADWRHLKEKIDAGADF
VLTQLFFDNADFFRFRDHLTRELGVQVPIVPGVVSILSGAQIQRFTAMCGASIPAPLAAR
LAELGGDDAAVAEFGIEYATRQCEGLLQADVPGIHFYTLNKAAATVRILQNLGRAR
>A0A5I5DXD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Miami|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A842IKT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robiginitalea sp. SC105|TrEMBL
MKVTEHIANARETLFSFEVIPPLKGRKIEELYRNIDPLMEFKPPFIDVTTSREEYVYIDR
DGLFEKQVTRMRPGTLGICASIKHKYDVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNVM
ALRGDAMKEQKYFEPTQGGHPYASELVRQIEHLNRGQYLHDVVETDNCPDFCIGVAGYPE
KHLESPSLRTDIKWLKHKVDLGADYIVTQMFFDNRKYFEFVALAREMGITVPIIPGIKPI
AVKRHLQLLPQVFRTELPETLIEAVEACKDNKAVRQVGIEWAIEQSKELREAGVPVLHYY
SMGKSDNIEAIARAVF
>A0A2V6CQ28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MNLLEELQEHVVCGDGAMGTLLLDQGLPMESCLEEVCVADPDRVRAIHRDYIAAGARVIE
TNSFGGNAVRLSRFGFENRVAEFNRAAAKLAREGAAGKDICVAGSVGPLGISALEAEERG
IDRARCFHDQIEALLDGGVDMIFLETFMDDVEMQIALEAKNSLSDCTTICSFACEPEGRL
ASGVPIVEAFAKLRSLGVQITGVNCMNGPHATVQLLQRIPIDGLLAAYPNAGYPKYIDGR
FIYHAAPDYFAQAAREMVAEGARLIGGCCGTNPRTIAAISKAVAELKPVKAKPVRVITPV
PPPPEKKVSATAEESLLDKIAAGKRVIICELDPPKTLALEKYFRGAQELVRSGCDAITLA
DNSLAILRVSNLAVGAMLKERFGITPLLHLSCRDKNVLGLQSELLGMAALGMRHVLPLTG
DPARVGDHPAASSVYDVNSIELISIIKKLNEGFSHAGKSLKARTQFVIGCTFNPNAKNLD
SQVNRLERKVAAGAQFAMTQPVFDVRLVKETKRRTAHLNIPIFIGIWPLMSARQAEFLHH
EVPGIIVPDEVRKRMADVPPENGSGVGMEIAREVVAAVGAEFPGVYLITPFLHFDCTCEL
ARFARKM
>A0A5Q4Z575|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sideroxydans sp. CL21|TrEMBL
MESPTTPISFEFYPPQTPEGVEKLTAARQRLAAMKPEFFSVTFGAGGSTQDRTLETIRQI
HAEGHNATPHLSCVGSTRDNVRALLFAYKDMGIKRIVALRGDLPSGMASIGEFQYANELV
SFIRAQTGEHFHIEVAAYPEFHPQANSAREDMLNFKRKVNAGANSAITQYFYNTDGYFRF
VDECRKLGVTAPVVPGIMPIMRFSQLARFSDACGAEIPRWMRKTMEGYGDDVESVQSFGL
DVVTQLCEKLIAGGVPGLHFYTLNQANASLEILKRLGYR
>A0A2N2X4M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-4|TrEMBL
MKVIDLINDRKKTLFSIEIVPPLRGNNIEGIYQRIDQVIEFDPAFINITYHKDEATYTQL
KNGKIVKRTISKRPGTVALTASIMNKYKVEVVPHLTCGGFTRDQAENALIDFNFLGIENL
LVLQGDAGRGQDVFIPEPDGHRYAVQLVEQVVNMNKGKYLDENLEQGNPSNFCVGVAGYP
EKHYAAASLDSDIQYLKAKVLAGADYIVTQMFFDNKYYYDFVARCRAEGIDVPIIPGLKP
IALINQVDVLPKIFHTDIPEALTNEIRKCRDNKEALEIGTRWTIEQARDLMKNGAPVLHF
YTLGAGSSIRKIVKEIF
>A0A2V5QRF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
QTIRDLESYMPHFVSVTYGAGGSTRDLTHGLVERIQHTTKLDPIPHLTCVCHNEEEIQAI
LLRYAKSAIGNILALGGDRPAGIAYDKSRESFQHAIDLVKFIRRFNESGAHPERRGFGIG
VAGFPEGHPATPNRLVEMDNFKAKVDAGADYVVTQLFFDNRDFFDFRERCALSQIHVPII
AGIMPITSITGCKRMAELAGGTRFPATLLRALQHCQNNPEMVRRVGIQYALEQSHDLLDN
DVAGIHFYTLNRSDATRIIFDSLGIPRHPNTPVSTV
>A0A0E3TR81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides chelonae|TrEMBL
MTTNPLDHDASVAELQDPGSIADRLAGVQPGDVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDLE
RDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEERLLRAAGDGPEENRDEVRKVGVDVTTSMAARLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A370FUP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. AG1013|TrEMBL
MTFDAVRGRNSAGWETQTPSIVDRISSSEASKSGRIPFSVEFSPPRDADAEARLWRAVRE
FERLGPAFVSMTYGAGGSTRDRTVRVTGRLAEDTTLLPVAHLTAVGHSIDELRAMCGAYA
DRGISNILVLRGDPPGDPLGEWVKHPDGVEYAEELVRLVRDMGDFHVGVASFPEGHYRAP
DLEYDTKYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVVAYDPEQGEKPIIPEIMPITSL
RSARRSLELSGSKLPAALEERLTRAAGDGPEENRAAVREIGIEVATEMSERLIAEGAPCL
HFITLNFARATGEVLANLGMSASTSV
>K6QU42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus casei 21/1|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A2V5U2A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHFIRDIYATARANKRPVISFEFFPTKTEEGERALLEKTIPALRQLKPDFCSVTYGAGGS
TRDKTLTIVDRIQRQHGLTTMAHLTCVNATKEEISAYLNEARSRGINNILALRGDPPGGT
GEFKKTEGGFEFSYQLVQFIRQVGGFSIGVAGFPEGHIACQEGKQVDWQRLKNKIDHGAD
FVITQLFFSNRDYFQFRDFLTNLGVTVPLVPGIIPILSTAQIKKFTALCGADLPKPLLNE
LEKRGDDDEAAVQYGIEYATRQCEELLREGAPGIHFYTLNKARSTTAILNNLRLR
>A0A2V5P0A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIIRGNSPTFSFEFFPPKTPEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQRTTKLDPIPHLTCVCHNEEEIEGILLRYAKSAIGNILALGGDRPAGIAYDKSR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHFKAKVDAGA
DYIVTQLFFDNRDLVDFRERCALNDIHIPIIAGIMPITSISGCKRIAELAAGARFPSQLL
RALQHCQDDPEMVRRVGIQYALEQCRDLLDNDIAGIHFYTLNRSDATRVIFDSLGFPYHR
NAHALIDMP
>A0A1L9RB86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus wentii DTO 134E9|TrEMBL
MHIKDKLAQNDAAARTGVSFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDVTWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAALSAAYKAGCTNILALRGDPPREKET
WEVVDGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSSF
VITQMFYDTDNFVSWLKKCRAKGITIPIIPGIMPIQTYAAFLRRANWTKAKIPDSWMEAL
EPVKNDDAAVREVGRHLVADMCRTLLANGINHLHFYTMNLAQATKGVLEELNLTPSEESP
LQKPLPWRPSLGLNRRGEDVRPIFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSVKDLTEMFVRFLEGKLDRLPWSDSPITQEADDIKTNLVA
LNSKGFLTINSQPAVNGARSSHAVYGWGPKNGFVYQKAYLELLVPPYLIDELVARIEKNE
DLTYHAVQKNGELKTNTEDSPNALTWGIFAGREIIQPTIVETISFLAWKDEAYRLGEDWA
KCHDAASPSRKLIQGVMDNWYLVNIVNNDFHNTYDLFELFKDLEVKDLETEVPADSVPEQ
PVAQN
>A0A2V6L1K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIIRGNSPTFSFEFFPPKTPEAAETLYQTIRDLELYTPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEQEIEEILLRYAKSSIGNILALGGDRPVGIAYDKSR
DSFQHAIDLVKFIRRLNESGGHPDRRGFGIGVAGFPEGHPATPNRLVEMDYFKAKVDAGA
DYIVTQLFFDNRDFLDFRERCVLNEIHIPIIAGIMPITSISGLRRIAELAGGARFPAKLL
RALQHCQNDPEMVRRVGIQYALEQCRDLLDNNVAGIHFYTLNRSDATRVIADRLGIPRRQ
NAQTASV
>A0A2V6EWB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMQGDSPTFSFEFFPPKTPEAAEIVYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCICHNEEEVEAILLRYARSAIGNILALGGDRPRDIPYDKAR
DSFQHAVDLVKFIRRFNESGTHPDRRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYMVTQLFFDNRDFLDFRERCALAGIHIPIIAGIMPITSMSGLKRIAELAGGARFPAKLV
RALQRCENDPEGVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRVIFDSLGIPRRQ
SAQAPTVSSSHKGRKRLAN
>A0A1X1HDP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLTIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3M7KFL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium PRS2|TrEMBL
MKVIEHINNAKDPIYSFEIIPPIRGKSAQEIIDIVKDLEPFNPPFIDVTSHPAEAYYEEG
SDGEIKRRVRKKRPGTISICGIIQNRFKIDTVAHLLCRGFTREETEDAIIELNYLGIHNI
LAVRGDETNYKKPVHSGRTVNVYASDLVKQLNDLRSGNYLDEILNADPVDLCIGVGGYPE
KHFEAPNLKKDIEYLKQKVDAGADYIVTQMFFNNADFFNFRDECRMAGIKVPIIPGLKIL
NNPKQLTSIPKNFFVNIPTELSEEIEKNLKHTREIGVEWCVKQCEELLDSGLMTIHFYIM
SGAKAVTKVLNKLNK
>A0A2V6JKT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITEIMRGHSPTFSFEFFPPKTLHAAETLYQTIRDLESYMPDFVSVTYGAGGSTRELTH
DLVERIQHTTKLDPIPHLTCVCHKEEEIDAILLRYAKSVIGNILALGGDRPSGMAYDKSR
ESFQHAIDLVKFVRLFNESGVHPDRRGFGIGVAGFPEGHPATPNRLVEMDHFKAKVDAGA
DYIVTQLFFDNRDFFDFRERCGLAGVHIPIIAGIMPITSITGLKRMAELAGGARFPAKLL
RALQPCQNDPDMVRHVGIQYALEQCHDLLTNDVAGIHFYTLNQSGATRMIFDSLGIPRNR
NLQASNV
>A0A2V5KT37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
PEAVRRVGVHFALEQCHDLLDKNVAGVHFYTLNRSDATRVIFDSLGIPRRQSAQAPTV
>A0A4R5X282|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium paragordonae|TrEMBL
MEYGPCGGVRPDGQCEMRSGACTFTDIMPWNGPVRGMVRGPVPLVLTDFSCAPFDRDDVA
ATAAVLSSSCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDRNRVVLEQELRG
LRTIGVDTVLCVTGDGRGYDVRPDVTQTFDLDGLRLVSLAASLGAVPAVPETPTAPPVAA
RPARLVEKQRAGAALAVLNHVPFPDMIAEFMKSARAQGLSIPVIAAVAVFTDSVSAAVLQ
GLPGLELDPAVTERVLSSADPIAAGISAAVSEARSLLSIDGIEGVNVSGLASASGTRVGA
EIKAEVGRLIREGVA
>A0A6L9Y1V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diaminobutyricibacter tongyongensis|TrEMBL
MSDHGSAPAPAGDAPCAGGVPFSFELYPPRNARAAAALPATIDRLAAAHPEFISVTYGAN
GSSRTSSLDVLRYILANTSVSPMAHLTCVGSSHAEANRLIREFLDAGVRSFLAVRGDPPA
DAAPGDSGLGDLRSAGELVQLIHRVQAERVPYEELLVPGIPTAREVRTEREHVRIAVAAF
PNGHPTSRSASQDIDTLLAKQAAGANLAITQLFFHPEDYLAFAQRAKDAGVEFPILPGIM
PVTSPARLRRMLELSGEDLPSELAIQLEIEPTEEGQREIGIAWASRVVAQLVAGGAPGIH
LYTFNQHEAVLAVLERTGLLHSASAT
>A0A6N8EVW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus macerans|TrEMBL
MKPDLREALKNEVIVGDGAMGTYLYHLGFPVGISYEEFNLLRPDVIGDVHRRYVGAGARL
IETNTFSANYYKLSKFGLEAKVEEINRAAVRIAREAAGDVAYVAGAVGSIRGGKRANVTA
QELGDYYEQQIAALLTEGVDALLFETFYDLREIRIALGKARLLTDLPVICQFAVDQVGRT
LDGYAMQEAFGALLREGADVLGFNCHSGPKGIMSVMAEMNGPLDVPMSVFPNAGLADYVD
GEYVYGATPEYFGENAASFADLGARLIGGCCGTTPEHTAATAKALLGYAAPPLADERKLA
AASSSAVLNEAAAPETESGAAESGLYGRPNRPSLVDLAKERHTVIVELDPPRDLDIGKFM
EGAAALKAAGVDALTLADNSLAVTRMSNMALGHLVQSELGLRPLIHIACRDRNLIGTQSH
MMGFDALGIDHVLAVTGDPARFGDLPGASSVYDLTSFEIIRMIKQLNAGISFSGKPLKQK
AKFVVGAAFNPNVKHLHKAVERLEKKIASGADYIMTQPVYDPKLIAAVKAATAHLDVPIF
IGIMPLASGKNAAYLHNEVPGIQLPEEVLKRMEGLQGPEGRRAGVEIAKELLDTAMEHFN
GIYLMTPFMFYEMNVALVNYVREKSKQGASHLSRST
>A0A5E4KI16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon|TrEMBL
MSFREKLNSKKFIITAEISPPKGTDITGMQNDASLIKDVVDAINITDNQRAVMRMSPLAA
CSVLSQKGYETIMHLTCRDRNRLALQSELLGASALGINNVLVMTGDHPAKGDHEGAKPVY
DFDSVQLLGLIKELNRGFDFSGNPLHGKPELCAGAVAGTGLNELSFIKLEKKIKMGARFI
QTQAVFDTQNFSGFMDKIKDSETFREVKILAGIIPLRSEKNAVFLNKNIAGIKVPEDMIK
QMRGARNPVFKGMEIAAELIKELRSMCDGVHIMPLGNHEKTAGILEMAGIK
>A0A7H1QCX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseofuscus|TrEMBL
MTTFSFEFFPPKTAAGEQALWRAVRRIEPLAPDFVSVTYGAGGSSRERTIQLTQRMVTET
TLRPVAHLTAVGHSTAELRRIIGQYADAGVRDVLVLRGDPPGDPRGPWQPHPEGLTHACQ
LVELVRSLGQFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFDVEDYLRL
RDRVEAAGCTTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAARERPDDAYRIGV
EHATAMADRLLAEGAPGLHYITLNKSTAALDIHRNVLSRSRSLHAR
>A0A1V4SLA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminiclostridium hungatei|TrEMBL
MNIFEGKDYFLFDGAMGTYYSSKYNGEIACEAANLTHSQAILEIHKEYIEAGANAIKTNT
FAANRFSLSCEQAEVELIIKKGFEIALSAAGNREVAVFADIGPIPSAQVIDQEEEYKKLA
DIFLSCGAENFLFETFPQYDIVLEISAYIRLKKPSAGIIASFAVYPDGYTKEGLFYQDIF
NRVNASGLVDACGFNCISGPAHMCRLVSSLELDGRLLSIMPNSGYPASERGRAVYVDNSQ
YFAGKMLELKNMGVRILGGCCGTTPHHIAVTAKLLADNISTAGSPEQQSGKATGKTGDKP
LLRRLVSEKKPILVEIDPPFDTNWEYMLRDAFLLKKAGADMITIADSPLAKARADSSIMA
AKLQREAGLPAMPHITCRDKNLLGIKATLLALNIEGIRNILVVTGDPIANIERKDIKGVF
SMNSSNLANYVSSLNANIFGEASFEIGGALNVNAPNFDAELRRSAKKLENGISFFLTQAI
YTEAAVNNTIRAIEELKVPVFAGIMPIVGYKNAQFINNEVPGIEIDEDTVESFRDKSREE
AELLGIEHSLKCINKLYGHVSGFYIMTPLKRIQVVCRLIKSIKEINE
>A0A452J4X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gopherus agassizii|TrEMBL
MSGPGACLGERAWIISTYTHTSAGEHIMVNEPHSASSGSASSRSDGSSSGSEGSKDSSRC
STPVLDAERHERLREKMRRRYDSGDKWFSLEFFPPRTANGAVNLISRFDRMGMGGPLFID
VTWHPAGDPGSDKETSSMIIANTAVNYCGLETVLHMTCCNQTKEEITGHLQKAKHLGLKN
IMALRGDPIGEEWEEEVEGFNYAVDLVKHIRCEFDDYFDICVAGYPKGHPEAESYEADLR
HLKEKVSAGADFIITQLFFRSETFLAFMKDCQAIGITCPIVPGIFPIQGYHSLRQLVKLS
KLEVPQEIKEVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVSGLHFYTLNREVATTEI
LKRLGIWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIHRTQEWDDFPNGRWGNS
SSPAFGELKDYYLFYLKSKSPREELLKMWGEELMNEESLFEVFTCYISGEPNRKGHKVTC
LPWNDDPLAAETNLLKEQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAY
LEFFTSSENITALLKVLKTKKYELRVNYHIVNVRGENITNAPDLQPNAVTWGIFPGREII
QPTVVDPVSFMYWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNEFPLEN
CLWQVMEDTFELLNCPTEQ
>A0A7W3KVB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter ciceronei|TrEMBL
MKIIKSLFERKSAAEPTAPADISGLLNGFSVEVLPKTVGRLLERSEGLPARSRVYIAYIQ
GTDIVDMVSTARRLTDAGFEPMPHIPARLVKDRQTLSDWVARYKNEAGVHQALVIGGGVD
HPVGEFSSSIELMATGVFQKAGFDRLHVAGHPEGNRDIDPDGTDKNTLAALRWKQEFSEQ
TGVDMAIVTQFSFDSQPVIEWAQRLSAEGIRLPIHIGVPGPAKLQTLIRYALHCGIGPSI
RVLHRRAADVTRMMLPFTPEEFLNGIAHHKAANPGSKIAVSHFFPLGGIDKVLEWNARFT
REVGLPDVC
>A0A2D7JGE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. MED650|TrEMBL
MDRPPFRHANPTGGGLILHSGPRESRPGLTTALQRAIETGQQVLTAEVMPPRGVDPSHML
EMAGCLRGRVHAINVTDGSRAVMRMSSLASCRLLLDAGLEPVLQMACRDRNRIALQADLL
GAHAMGIRNLLCLTGDPVRAGDQADARPVNEFESVKLLQQVHALNHGVDPVQGDLPDGAS
ELFAGCAADPQSPSWSGLQRRLQRKQAAGARFVQTQMVMDAFALERFQRELAAPLMLPVL
AGVFLLKSAKNARFINRVVPGACIPDALIRRLEESADPAMEGVAIAAEQVKQYLGIVQGV
HLMAIKAEQRIPLILDQAGISSRPG
>A0A2J8DJ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium dahliae|TrEMBL
MTQLFFDIDAYDHFEQVLREHPSGAFKTIPIIPGLMPIQSYQMIKRTTKLSHAKIPDALM
ARLDAVKGDDEKVKEVGVDIVSELVDQIRAVKSKRTTGPQGFHFYTLNLEKAVSFILERT
NLIPDKEQEDEEAVIDDATTPPVVPTVQINGLHPGSHHRPGRRQSSIGSDPHNRVIVSSA
SNHAYETNPEGAGLPAEPIDTRANTLAISEGEGVLGREATWDDFPNGRWGDARSPAYGEI
DGYGVSLHMSVTQAVRLWGHPKSSEDISTLFIKHIRGELSAIPWSEEGLSPETNIIQEQL
IELNTRGWWTVASQPAVNGVPSRDATFGWGPSHGFVFQKAFVELFLPAADWKVLSERLTG
PEVEGTVCFYACNGNGDFATSDDSGGLVRTAVPASTNAVTWGVFPGKEIITPTIIEEVSF
RAWSEEAFKIWGEWSRVYGRGHESEKFLKSVKDEYWLVNIIHHDFVETNALWDLLRG
>A0A1G1SXC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter lapidarius|TrEMBL
MKVTDHLAQADGKTLFSFEVLPPKKGENIHTLFSNIEPLMEFKPPFIDVTYHREEYVYRH
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDT
VLALRGDPIKSEGMFKAEPDGHAYAADLIGQVSDLNKGEYLDQEQDDSWATNFCIGTAGY
PEKHFEAPNYQSDIRYLRHKVDRGADYVVTQMFFDNEEFFRFERLCREAGITVPIIPGLK
PLTTKSQLTMLPRTFYLNLPEPLVEAISQCRDNEAARAIGIEWCINQSRELVAHGVPCLH
YYSMGKSESIRRIAQELF
>A0A1J4TNA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium CG1_02_35_72|TrEMBL
MKVTEHIAKANGKTLFSFEIIPPKKGHNIQQLYDNIDPLMEFKPPFIDVTTSREEYIYIE
RNGLLDRKVTRMRPGTVGICASLRYKYNVDTIPHILCGGFSKEETEYVLVDCQYLGIDNL
MALRGDAMKHQRFFEPTKGGHEYAVDLVKQIGDLNKGIYLHDLMETPTKADFCIGVAGYP
EKHMESPSLPSDLKRLKEKVDAGANYVVTQMFFDNQKYFKFVKAAREMGITVPIIPGIKP
LAVSKHLQILPHVFSLDIPQELIDSVSHCKDDKAVRALGIEWAIHQTKELLKAKVPVIHY
YSMGKSDNIKSIAKQFF
>A0A1V6S6J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium vulpinum|TrEMBL
MHIREKLAKNEAEGKIGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEAAENGFCYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNTDVDQLIDHLKEKVDAGSSF
VVTQMFYDADNFIEWVKKCRAKGINVPIIPGIMPIQTYASFIRRSNWTKVKVPPQWMEAL
EPVKNDDSAVRDIGKTLIADMCRQLIAAGLKHLHFYTMNLAQATQLVLKELNLSPSDESP
IQRALPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISNVFVDFLSGKLDRLPWSDSPITTEAHEIQEDLLK
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKND
DLTYHATNKKGELRTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCHDAASPSRRLIQQIMDDWYLVNIVDNDFHRSDGLFELFNGLEVKDLNVEVAEKPLTNG
HAEPEQNGVSAN
>A0A368KK77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastopirellula cremea|TrEMBL
MLSDFYQPGQLPVSFELYPPKTEKGMQSLMLQVEQLVKFNPAYITCTYGAGGSTRGRTLD
IVESVKKSFSVPVAAHLTVVGSSVDDLRSFLTEAQQRGVDYIVALRGDPPQGETSFKPNA
DGLRYANQLVELINAEFSDLGVLVAGYPETHREALSPEADLDNLKRKVDAGAQVIVSQLF
FRNADFYAWRERCDKAGITVPIVPGIFPVQSLAQISKIAKLCGANIPAELSEKLNEKHDD
TAWQAQVGTEYAAQQVIDLVDNTVPGFHFYVLNQADATGQILTQLKDHLDGKTSGDPVNA
>A0A1G5AUD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium anhuiense|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKHEQSFTPKDGGNHYAVDLVKQIKDLNCGQYLHEVIDTDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAVQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A3A0DK99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MKVSFLEHLQQDLLVADGAMGTMIYSQGVALSQSFDQLNLTQPDLIRGIHQAYVQAGAQA
IETNSFTANRKRLARFGLENSVAEINLAAVRLAREAADEQAYVLASIGPVRDRASEEMES
ADIRQLFAEHISALAQGGPDALLFETFTVVSELEIAVEEARRLSSIPIIAQVVADEEGYT
SDGQHVTAIFKRLRELGAAVVGINCAKGPAGILKALRDVPLEESLLLSAFPNAGLPAFVD
GRYIYLSTPEYFGEAALKLRQQGVRLIGGCCGTTPEHVQMMANTLRGLKPVTEKTIVLRP
APAPPSLQKIIEPDFLQKVRTQPSIIVELDPPRDLDFEPIVEGARALKRAGVDALTMADC
SLGITRMNNLALGYLVKQKVDIPLIIHLACRDRNLVGLQSELMGLHALGIHTVLALTGDP
AKFGDQPGATSVFDLNSFGLVEMIKRMNQGIAFSGRAMKQGARFTIGVAFNPNVERLDTQ
IRRLRKKVEAGADFVMTQPIFDWRMTKEIYDATREFDIPIFIGIMPLVSGRNADFLHNEV
PGIRVPEKIRKRLFRFEGERARREGVTIAAEILESVLDYFNGIYLITPFVRYEMCLELVE
KCRGLVRRSK
>A0A7J7LCJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingdonia uniflora|TrEMBL
MPVEKIDHALDSIKSYGIHNVLALRGEPPHGYDKFVKTEVRLRSRSGKAYEGKVCAHNSC
YESMLT
>S4YCL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum So0157-2|TrEMBL
MVSKSKMERLLSERQFLVSAELTPPRHYDLEKLLKHARNMAGCVDVVQINDHLLSQARCA
NMAVGHFVKQEGLEPVLQFSLRHKNRIALQGDLLGMAALGLSNIIILGGYPCAIGSDPEA
KEVSDVDSYAAIELTRRMTREGRLYNGDVISPAPYFHVGTIDFPCGEQAIAGAMDRLSAK
IDAGASFIQVQAVFELAPMRRWMAAVVERGLHERAHFIAAIFPFAGVDRLSFLQKVPGLV
VPEHLIERVRQSGDAEGESYRITLELVRGLRDVPGLSGIHMRSIGAEDWVPRLVEEAGLR
RAA
>A0A2E3K648|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MKSDNRNAINELPFPAGSPQNLSVSFEFFPPKTQKMNKILWDSIKRLEPLNPSFVSVTYG
AGGTTRERTHETVARVINKTSLTPAAHLTCVAATMEEVNAVARSYWDTGVRHIVALRGDP
PEGQRNYTPHSGGYDYAVDLVKGLKKIADFEISVGAYPETHPGAESLEADIDNLKMKFDA
GAERAITQYFFGAEPFLHFMDRVRAAGISNPIVPGILPIHNFNQVVKFSEMCGTSVPDWL
RNLFEGLDGDLETSRMVAATVAAEQCRQLQAYGYNEFHFYTLNRADLSYAITHLLGMRPS
S
>A0A7Y5L933|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
LRPAPAPPSLQKIIEPDFLQKVRTQPSIIVELDPPRDLDFEPIVAGARALKRAGVDALTM
ADCSLGITRMNNLALGYLVKQKVDIPLIIHLACRDRNLVGLQSELMGLHALGIHTVLALT
GDPAKFGDQPGATSVFDLNSFGLVEMIKRMNQGIAFSGRAMKQGARFTIGVAFNPNVERL
DTQIRRLRKKVEAGADFVMTQPIFDWRMTKEIYDATREFDIPIFIGIMPLVSGRNADFLH
NEVPGIRVPEKIRKRLFRFEGERARREGVTIAAEILESVLDYFNGIYLITPFVRYEMCLE
LVEKCRGLVRRSK
>A0A2G3BXW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum chinense|TrEMBL
MLILARILQVDAGVDRIITQLFYDTDIFLKFVNDCRQIKINCPIFPGIMPINNYKGFLRM
NGFCKTKEIANALCGQDSENSQEALRVRDIILRKHVGKQVKKSMKLLSVYAASRFAVEVD
>A0A1G2XCS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium GWC2_45_44|TrEMBL
MEQNTKLSRLLSKQVVIGDGAMGTMLYSKGVFVNTCFDELNITRPGLIKDIHEQYVSAGA
DFIETNTFGANEYKLAKFGLFDKVEQINASAVKIAKEAAGGNALVAGAIGPLGIEGSAKL
SEKQIIEIFERQIKSLADAGADFLLFETFGNLAELLLAVRAAGSVCGLEIVAQLSVNENK
ETLFGDRLDEAIIELCRCSHVAAAGLNCLLGPAAMLDCLDVLKTVATKPISIQPNAGLPQ
TVDGRTLYMSTPEYMAEYAKRFYQRGARIIGGCCGSTPEHIRQIAQAVKSIDKSERPPAI
EIRQVEKAVRQIPVELKDKSQFGAKLAAGQKIITIEISPPKGADLSGLIEKVNLCKQAGV
DAVNIPDGPRASSRISAMITAIKLQQACGIETLLHFCCRDRNIIAMQSDLLGIHTIGLRN
VLIITGDPPKLGEYPNATGVFDLDSTALTKVVSDLNCGLDIAGNGFTPKTALVVGVGANP
VAAEMKRELERFKKKIAAGAEFAITQPVFDSRSLFDFLDAADCRIPVIAGIWPFTSFKNA
EFMANEVPGVVVPKNILDRMATAKDQLQSKKLGVQIAKELMEQIKDRVAGFAISAPFGNV
KMALAAADKFDIQLG
>A0A0C1J312|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria sp. ANG-R|TrEMBL
MTKPEISFEFFPPQTLEASFRLWDTVQTLAPLNPRFVSVTYGAGGTTRELTRDAVSTLHK
SSGLPVAAHLTCVDASRQETLEIADTFARAGVQDIVALRGDPPKGQDRFEPHPDGFANSV
ELIAALAETEMFSIRVGAYPDIHPEAQNARTDVDWLKAKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGILPIENWKGARNFAKRCGTRIPDWVENAFDKAIRDDREDLLAT
ALCTELCSDLIDGGVDKLHFYTLNRPELTRDVCFALGITPQTELQNVA
>A0A2E4BUG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MERNSNLTNQLDSPPIEXQLVRRLLGGQFALTAEVTPPVSAGSDEXLAKAEPLRGIVDAV
NVTDGASARVHLSSVISAAILNANGIEPVVQFTCRDRNRIAXISDLLGVGAQSIHNLLIL
TGDDPTVGDQPQAKPVFDLKSHELITIAHKMSQDGIIPSKSVKMTAEGVDPNTRKIETPP
KFFIGAADVPTVKIDEQWLVGLRKKKACGXQFIQTQLSYDMDIIRAYANLLIEEGFTENM
FFLIGNGPLPSARSAIWMRENLWGVVVPDKIIKRLETAKDSKLEGIKICSEHLQELSQIS
GVAGAHLMAPINVKSIPASIEMASLGDRS
>A0A2D9Y8K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MXASLKQISSLLNGFSTEVTPASAKNVECFRSYLSPGTSVNVTFLPGSNIEDTVEVSVRL
KNEGFNPVPHIVARNFKKIEGLELFLDQLVSKANVFEVLVIAGGIAKPLGPFSNSLQILN
SGLLEKYSIKKVGVAGHPEGSPDISEANLARAMGDKNEWARNSDMDVYIATQFCFDVASI
ITWEEKIRRNGNKLPIHVGIPGPATLKTLIKFAKMSGIGPSIRVLTRQSKNLAKLVFTQD
PYDIVAGIANAKAEDPKSLIKQLHFYPFGGLAKTXAWVNSVLDNQ
>A0A0H2ME31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiloniella spongiae|TrEMBL
MKRPDISFELFPPASENGLENLTKTVTRLKAFEPKYYSITYGAGGSGQQKSKDLLNELSQ
DKDLTLAAHITMAGASKAEILETVKSWRDLGVTRLVALRGDAEEPGTAFKPHADGFQDSI
EFIASLRELGDFEIAVAAYPDPHPDSKSLADDLAFLKRKQDAGATTAITQFFFEAESYFR
FVEKARKAGITIPIIPGILPINNIAQLQRFADRCGATIPDWVSNAFEGLEDNPETAAAVA
VSLCLDLCRDLIDGGVDAFHFYTLNRSPLTEAVCRLLSIQAEEKEAA
>A0A2E4F1X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTYKAPRGACNSCGVPHSQGRLERLLRAGTFTVTAETTPPVSADPSTLLKATESLAGLAD
AVNVTDGAGAKSHMASLAAASLLVQVGIEPVLQFTVRDRNRIALQNDLLGAAALGIPNIL
CLTGDNVDTGDQPEAKMVMDLDSRGLMALTRDMRNQRQLPSGRPIATPPGLFIGAADTPQ
DPDKDWDPSTLRAKIEAGAEFFQTQFCFDIGLVRRYMDRLDEEGILEESYFLIGIGPIPS
VKSALWMNKNLYGVHIPDGIIDRLEKASDQQAESINICIELIQQLREINGVSGVHIMGPQ
VEKAAAQVIANTGIMKERE
>A0A415REY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mitsuokella sp. AF33-22|TrEMBL
MKRISVELVPRDEEALRQELALLQQYQEKVDVINIPDLLRFPLRSWQGAAVAKDFFPASM
PHIRAMDINLEEELSMKEYLRAHDIREVLVIEGDPPQDMMHEVYPTNSVDVIWKFRKEMP
EVKVYAGIDQYRGSMAQELYRIKRKLQAGAAGFFTQPFFDMRYLAVYADMLQGLEVYWGV
SPVMSARSQSYWERKNNVVFPHSFQPTLEWSVDFAHEVMEYAEREQANVYLMPIKTNLAA
YLAGVFA
>A0A2G6Z0B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp. 26|TrEMBL
MSYPVSFEFFPTKTPEGAAKHVAVRQALYVRKPQFCSVTYGAGGSTQAGTFTMVQDIQSE
GVSAASHFSCIGATQDSVREELTQLKAMGVKRIVALRGDLPSGYGLGGAFHYASDLVAFV
RQEFGDWFYIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VKALGLDVPVVPGIMPITSSTQLMRFSDACGTEIPRWIRLRLQAYGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A098BMX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus ruber|TrEMBL
MVDRLRAPRGARIPFSVEFSPPRDADAEARLWRAVREFERLGPAFVSMTYGAGGSTRDRT
VRVTGQLAQETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWT
RHPQGLEYAEELVRLVRDLGDFHVGVASFPEAHHRSPDLEHDTRYLVHKLRAGAEYSITQ
MFFDVEDYLRLRDRVVAYDPEQGAKPIIPEIMPITSLRTARRSLELSGSKLPATLEERLV
RAAGNGPEEDRAAVREVGIDVATEMAERLIAEGAPCLHFITLNFARATREVLARLGIAVP
TAV
>A0A3D2BXN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTERHSLKSLPAPISDGKDLEVSFEFFPPKTEKMAETLWKSVQRLEPLSPRFVSVTYGAG
GSTRERTHSTVNRINTETSLSAAAHLTCVGATQEEVNAVAEAYWEAGIRHIVALRGDPPD
NEPYSPHPGGYGYAADLVRGLRDVADFEISVAAYPETHPEATSSSDDLDNLKRKLDAGAT
RAITQYFFDVGIYLDFLDRARKSGIDVEIVPGILPVTNFAQVLKFSAMCGTKVPDWMEQL
FDGLDDDPETRRLVAATATAEQCRLLHSEGVEAFHFYTLNRADLSFAICHILGVRPQGSA
A
>A0A3A1XJN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium NR021|TrEMBL
RTATARIAHTIRSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGILALRGDVIAGQE
AAGVFEHASDLVSYIRSKRPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQ
LFYDNEDFLRFRDLARAAGINVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMNRWG
SNADCLRDAGSIFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A363NRQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium athyrii|TrEMBL
MKITDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTEGGHAFATDLLEQVADMNKGKYLHEDIITSEKTDFCIGVAGY
PEKHFESPNFNTDFKYLKQKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVASCKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLV
>A0A2D7FRL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MTGISFEFXPPKSPEAEEKLWRSVGRLEPLAPDFVSVTYGAGGSTRDRTHTCVRRLVDET
GLQPAAHLTCVAASRAEVDSVVEAYAEAGVRHIVALRGDMPDMGGXAPHTDGYDGSVALV
EAISARGGFDXTVSAXPEKHPESRSLDDDIDLLKAKXDAGATRAITQFVFDTPAHMRXRD
AVAAAGVSIPIIPGIMPTTNFAGARRMAAACGTCVPDWLSAAYEGLEDDLDTRKHIAASI
ATDQCRTLIDEGFEYLHFYTLNQADLTFAVCRILGLGGDQQESDVV
>A0A7X8QSL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MTSNTLLERLAEGPIVGDGAMGTYLHELGHDIRDGAEDLVISDPDTVRRVHRAYIEAGAE
LLESNTFAANRLALAPLGESFDVRALNATAVRLAHEAAAGRTWVAGAVGPIIPRPDDHFT
DSELLAMYVEQVEGLCEGGADALIFETFTTLDDLLLALQAGRQVAGARLPFIAQLVYGGG
AAASGESSQEAAARLLAAGADVVGANCGRGLQSMRQALDGLLAAANERGYVSLYPNAGYP
ELIGGRTVYMGTPDYMARQAAQWARQGVRLIGGCCGTTPETIRAIHQALAGLRKIPASSK
HVVGRSQPATAVTSVATKQKTPAECGGFLRAVADVKLPVIAEIDSPPHLDWQPWAEGARA
LLTAGASAISLAENPLASVRMENTFLAAWLRRETGRQVICHMTCRDRNSLGLQSALMAAH
AADIEAVLAVTGDPVQRGGHQRVMAVYEQTSVGLVRLMTALNGGRNASGRDLKGTTDFSI
GVAYNSAAANLAAESDKLRRKRDAGAHFVMTQPVYDLDQARQVLEQTATCGMRIFLGFLP
PVTAKLAHYLHNEVPGIRLNQSLLEQIDSYDQPGDQQKLALDWTWQLIDTLRQEMGGVYL
ITPGARWRALLPLLAQLQEF
>A0A7X7KVB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MSTYLQQLNQRPLILDGAMGTAIYEAGVFVNACYEELVLTNPALISGIHRAYGEAGADLL
LTNTFGANRVKLRGFGLADRVAAINAAAVRLAREAAGPGRLVGGDVGPCQEIAAKLTEAL
APEIEAAFAEQMQALAGAGADLIFLETFSDAREIQVAARAARATGLPVHASVTVDGRGET
ATGLSVTTIMELLEADPNIDTVGLNCAVGPTGLLKIVQTMLPRLTKPLLVKPNAGFPQQV
GGRMLYLAGPEYFTEKAKAFIHLGVRGVGGCCGTTAEHIRVLAQTLKCLGEFQSPTPGLQ
AVNTREETPMTEAVAQADKSRLGARLARGERVSSVEILSPKGPDMTAMIDKARQCEAAGV
DAINIPDGPRATARVAPLVAAMLIRQAGLSIEPVPHYCCRDRNLLGMQSDILGAAAAGIR
NLLVITGDPPKAVGMATEVRGVFEVDAVGLTRLIHSLNCGFDLSRHPITPPAAMLIGVGA
NPCALDLRHEVDRLFRKIEAGAEYVITQPVFDPDALLRFLDLAANAPRRVPILAGLFPLI
SLKNAEFMRNEVPGVVVPDAVITRMAACPDRESARAAGIEMTRSVLERVADRVDGAQVSA
PMGQVDTALRVLDGYIRP
>A0A8F9ZV61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella sp. ESL0443|TrEMBL
MKTNLLFNKKNVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHAVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPTVTPKDDF
RYASELVSFIKENGDFNVIGACYPEGHLEVSTLKQDLIHLKEKVSAGTDQLISQLFFDND
YFYTFLDKARDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKSE
>A0A7X9AVW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MIQQTRQLNMSFEGDCRLASAMRSGQFCFLLEMNSPPSNQPLDSYMAAAAPVFKKVGMLP
GVHGIAVTDRWPTAQRQDPVDFAAEAMKSSGKPVLMTLSGRGADLARAKTLLAEARAKGI
RCFLAVTGDWLGKNGAEGVPTTYLDSVTTTVTACQFGSDAWVGAAINPYKYTCEGVFLQY
AKLQRKITHGADFLVAQAGWDMKKAQELQWFLQMRELYLPTLARVVLMSQEDALKLGEGF
WPGVPMPIPLGALIMREAAGTADEFLEAQLSRTALQIVGLRLLGYSGVQVTGVRTPSLLT
QLVDRVHDCTAECPDYDAWLEAWRQRHGDISFGPGVSDLCPDPPYYLFANLQQPERRDFD
PEFAQIAFNTIAPPTLYDRWTRWLHRPTRPRLIREAVRRLTFRSEADEAAASLCQGLLNR
SCPKGLVYGACGGANTDGLCEDGSRECFFHRVIRLANAANDLEALENGEVTQ
>A0A845KTX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea sp. BIOML-A1|TrEMBL
MKISDILVEKTPHLSFEVFPPKTDAAYEGVLKATEAIAELKPSYMSVTYGAGGGTSKNTV
KIASHIKDKYNVPSLAHLTCVSSTKEEVHQVIDQLKASGIENILALRGDIPQESEFPLPN
HYQYAYELIEDIKSQGDFCIGAACYPEGHVESEHKKDDIAHLKQKVDCGVDFLTTQMFFD
NNILYNFLYRAREKGVTVPVIPGIMPVTNANQVKRILSMSGTNLPERFKAIVDRFGDNPK
AMQQAGIAYATDQIIDLFANGINHVHVYSMNKPEVAAAIQANLSEILNK
>K9CYB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp. F0473|TrEMBL
MTQGRADIREHLKAAPLIFDGGMGTYYAQRMHTRGKGVELANIETPIVVGDIHTEYLRAG
AQAVKTNTFAANRIVYQGDEKLVRRIIGAGWEVAVRAAAPFDAFVFADIGPVMGLPHADI
VDEYRFLADSFLALGARHFIFETNSSDEGLIETAAHIKQKCPEAFVLNSFSAYPGGYTRD
GRFVEDLVRAVAGSGSVDAVGFNCVNGTRQMKELIRHLGTLPLPLSLMPNAGHPVIVDGR
TFYESAPDYFGSSLAAARRDGVAILGGCCGTTPAHIKALCDALAAQGDIAPEEDEEAPLR
IAALPKSPFYEALKSGVKPIAVELDPPETGNADKFMEGARELIAAGVDAVTIADNPIARA
RMDAAMLAGRLHRELGIEPIPHMTCRDRNLNAIKSLLLGLSAEGVHNIITITGDPIPTAE
RDEVKSVYQFNSRKLASFITSLGNRGEVVPFHIFGALNVNAKFFGTQINLAKKKVEEGMM
GFFTQPVLSEHAKENMRAVRETFPEALLLGGIMPVVSERNARYMESEITGIHVEERIIDM
YRGLDRTAAEELAVKLSLEIAADIEPYIDGYYVITPFSRTALVARIVKELRQRRNRT
>A0A8H8R1I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnellula hyalina|TrEMBL
MEKITDKIAALPPGTPYFSLEFFPPKTAMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
AEKSLELAELCQRELGLTTCLHLTCTNMSKELVDKALEDAKALGVRNILALRGDPPRSNE
YGAETAGEVEEFEWAIDLVRYIRKVYGDYFCIGVAAYPEGHADESHPEGQSVEHDLPYLV
EKVKAGADFIMTQLFFDVEAYDAFEKRLREHESGVFKTIPIIPGMMPIQSYQMIKRTTKL
SNAKMPLSITERLDVVRGDDELVKKVGVDIVSEIITHIKDEPGPGPRGFHFYTLNLEKAV
SFILERTKLIPASPPDPDSEYAIIDLPLQLDTNGSEPSQKKPSRRQSSVGSDPYNRIIIT
ASSTSHPSHEATASEAGRPAQAVNTRANTLAISE
>A0A7V4HHN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
DKDLETFATKYRRALDEGFGLSLPDNPMGRLHFQATEVLPELGLPVPPGKALLHLNTFHT
KEHLDGILKTAGEIGITHILVVSGDGSERLPKLKPEDIGMSVNSVTSVELIQYINARHPN
AFTLGVAFNPYEPLDHEIHKMERKIAAGARFIITQPIIERHQALEELRRFNTPVMLEAWM
SKRIDLLAQCIGYDLPQNQAYDPLQNLRTLRTNYPDSKMYLALVGFKTQIPEIKNILGMQ
>A0A8C1BDP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVQDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGGMNGDFAGGDYKTALFYGDFF
CVNLVTFRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPA
FGELTDYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWN
DDPLAPETNLLKDELEKVNCRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFF
TSSENVTALLQVLKKYEPRVNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVD
PVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLINLVDNDFPLDSCLWQVI
EDMFTLLDSPPETQEEGSQS
>A0A1J3F6V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noccaea caerulescens|TrEMBL
KVVDKIKSVIEEGKTAFSFEFFPPKTEEGVENLFERIDRLVSYGPTFCDITWGAGGTTAD
LTLDIASEMQNVICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDKF
VQVEGGFDCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLKK
KVDAGADLIVTQLFYDTDIFLKFLNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTKI
PAELTAALEPIKDNEEAVKAFGIHFATEMCKKILAHGITTLHLYTLNVDKSATAILMNLG
LIDESKIYRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKAWNDFPQGRWGDSRSAS
YGTLSDYQFMRKRSRDKKLQQEWVVPLKSIQDVHEKFKELCLGSLKSSPWSELNGLQPET
KIINEQLGKINSNGFLTINSQPSVNAANSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDT
LVEKSKAFPCITYMAANKAEKWISNMSQSDVNAVTWGVFPAKEILQPTTVDPASFKVWKE
EAFEIWSRGWANLYPEDDASRKLLEEVKNSYYLVSLVDNDYINGDIFSVFA
>A0A2L2LXJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. SWBY1|TrEMBL
MTKQVPISFEFFPSKTDVGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLSTISDFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYASDLVH
FIREHSGDHFHIEVAAYPEMHPQADHFDQDIKNFVTKVNAGANAAITQFFFNPDAYFYFV
ERIQKQGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIIKLCERLIAGGAPSLHFYTMNNTEPTRQLVTDLGLA
>A0A1M7XY76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila aestuarii DSM 18488|TrEMBL
MSTETNSKSESNLEKVLKSGQFAFTGELGPPRGTDAEEVREKSKFLKGHVDSVNITDNQT
AVVRMSSWAASLIAIQEGLEPNYQMVCRDRNRLAMQADILGGSALGIRNMLCLSGDHQQF
GDHPDAKGVFDIDSIQLIAMVKQMRDEGKFLSGNDIHQPPKMFIGAASNPFAEPYEWRVH
RLAKKIEAGADFIQTQCIYNMDRFREFIRVANEEGLTEQVYILAGVTPMKSVGMARYMKT
KVPGMDVPDEIIDRLKGVEKNKVADEGIKIACEQIEEFKEMKGVHGVHLMAIEWEHKVPE
IAEQAKVLPRPVFD
>A0A1T4RPZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cincinnatiensis DSM 19608|TrEMBL
MGYTHASHIDSLNQSIAEVSDINVSFEFFPPSSPQMEETLWNSVHRLKNLKPKFVSVTYG
ANSGERDRTHSIIKTIKEQTGLIAAPHLTCIDATRDELVAIADDYWRNGIQSIVALRGDI
PPGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPQWMAKQFDG
LDDDPVTRQLVGASQAIDMIRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPTL
>A0A0T9QUR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia massiliensis|TrEMBL
MSFYHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIAADYWKSGIRHIVALRGD
LPPDSGKPEMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A3N4MA06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga barathri|TrEMBL
MKVTEHIKQAQGTLISFEILPPLKGKSIESIYDHLDPLMEFKPSYINVTYHRSEHMFKKR
ADGSFDKVEIRKRPGTVGICAAIMNHYQIDAVPHLICGGFSKEETENALIDLNFLGIDNV
LVLRGDAPKNETFFEAHPNGHRYAQELLQQVLNMNNGIYLEDDLMGGIKTKFCIGVAGYP
EKHFEAPNLQTDMAYLRKKVEGGADYIVTQMFFDNKKFFDFVAKCRENGITVPIIPGLKP
LTTRKQLTILPRTFHVDMPEDLATEVLKCKTDKDVEIVGTEWLIQQSKELKAAGSPVLHY
YTLGKPHVIQQVVSAVI
>A0A0Q9AEJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. Root265|TrEMBL
MSNVRGGATRGVSRTTSVVDRIAEIGRNRVPFSVEFYPPRDADAEARLWRAARVFERMTP
AFVSVTYGAGGSTRDRTVRVVRELARDTTLLPVAHLTAVGHSVAELRSMIGAFADCGITN
VLALRGDPQGGVHDEWIKHPHGLEYATEMVELVRGLGDFHVGVASFPEGHPRAGGLANDT
ANLVAKLRAGAEYSITQMFFEVDDYLRLRDRVAAVDPEQAAKPIIPGLMPITSLRTVQRQ
VELSGSAIPPALLARLTAAAGDGPVENRDEVRKIGIELATEMSVRLIAEGAPCLHFCTLN
FARATGEVLANLGMSLAA
>A0A4V1NQC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TM32|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWVKHPDGVGYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVD
KCRAGADFAITQMFFYPEDYFRLRDRVTAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A2M7JSU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_8_14_3_um_filter_45_9|TrEMBL
MKAGSNLEKVLEKRLFAVTGELGPPKGNDVSVIKRKAELLKGYVDAVNVTDNQTAIVRMS
SIATSSLLIQLGLEPVMQMTTRDRNRIAIQSDIFGATALGIKNMLCLTGDHHTFGNQVDA
KNVHDLDSIQLIDCVRTMRDQGRLLGGEEKIEGEINIFIGAAANPFADPFEFRVIRLGKK
VAAGVNFIQTQCIYDMNRFKEWMRMVRDRGLHEKCHILGGVTPLKSGGMARYMAKNVSGI
IIPDEIIDRVVKAKKPAEEGIKICVEQIQELREIEGVHGVHIMAIEWEQMVSKITEMAGL
LPRPKIE
>A0A1F8NGG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_68_17|TrEMBL
MSASLGSNGYKSGSRLERILRAGHFAVTAELGPPQSADGELIRKKAQLLKGVCDAANLTD
NQTAIVRMSSIGAGAIALQEGLEPVIQMTCRDRNRLAMQSDILGAHALGLRNLLCLTGDH
QSFGNHPTAKNVHDLDSMGLISMVRSLRDQHCFQCGDEIKGTEPRFFIGAAENPFGDPFE
WRPYRLAKKVKAGADFIQTQLIYNMERFAEFMEKVRQLGVHQQIYILAGIGPIKSPGMAK
YMRDEVPGMDVPAGLIERMEAAATGIAKDDKKARGAAWRKEGIQIAIELIQQARQIEGVA
GVHIMAIEWEEAVRPIVEGAGLLPRPEPTPLPAAGAPAQAG
>A0A2T4ICN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera lacus|TrEMBL
MHTPELSIEFFPPQTTEGAEKLRTVRDQLAVLQPAFFSVTYGAGGSTRERTFATVQEIAA
AGFEAAPHLSCIGSSRAQLRDILDEYDAAGIRRIVALRGDLPSGVGTAGEFRYANELVEF
IRAESGQRFRIEVAAYPEWHPQAKSPRDDLIAFQRKVAAGADSAITQYFYNIDAYLHFVD
EARALDVDIPIVPGIMPISSFSKLARFSDACGAEIPRWMRRKFESFGDDSASVKAFGLDV
VTELCQRLLEAGAPGLHFYSMNQAEATLAICERLGLMPQAH
>A0A800BRL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MKLTELFAKGKFVVTSEIGPPKGVDVQEMFEVADLLKERVDAVNITDQQSSVMRLGSLAT
CHLLKERGLEPIFQLTCRDRNRIALQSDLLSAYALGIENVLCLTGDYVALGDHPDAKPVF
DLDSVSLLVAAKRLQEGYDLAGKELKGKPDFCLGAVVTPGAEPLEPQIIKMEKKVRAGAQ
FFQTQAVYDPRRFEEFMRQVRHLNVPVMVGIVLLKSAGMARFMNRNVAGVHVPESLIEEM
EEATDRRAKSIEIAARLIREMKDLCQGVHIMPIGWERLVP
>A0A0E3RQY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina mazei LYC|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRFSASLEDASQLKGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDYPTCGDHPGSKP
VYDVDSVQLIELVRKLDTGVDFAGNKLDGGTSFCAGAVSGIDPEKTMQLIKLQKKVKCGA
DFIQTQAVYDIGMFEEFMDAVNYLEVPVIAGLIPLKSLGMAEFMNKNISGIHVPEEIMLR
MKDASSPMEEGLLIASETIKELTKLSRGIHVMPIGSHRNTARLLSLAGISQK
>A0A7C4A854|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MWQRLASSFHRVITAEAWRQACLCLEVALSNRIDKALFKCRACGQCLLFQTAFICPLTCT
RELRNGPCRGSNPHHCFIKPTRACTWYLIYTRAEQQGALERLLEVNAPSIKPGDLLEMGG
GTPHSQSYLQGYGPRLLDRFFNPARYYAEWEEYHNRQRAQSWWQGDSRYHPPAYSEPASQ
LESHLRGGEFVISVEVAPPMEPTGVRIARLAEQLEGCVDTFNFTDNPRGVARMGGLACAI
HSLANGIEPVLQIQTRYRDRHNLEAEAVGAHLVGVHNILCMCDDAGRLGPGPPPPPGPAD
LDTVQALWVLRRLRDEGVNVDGLQVEHRPRYFLGALVSPCATLPHYAALITQKKINAGAQ
FLQTLPIFDLGRFCNWMEALDKRDLLGKAYLVVTVEPPKNANHLRFLASEVPGVVVPPGL
HTRMAYSNDPREEGIQITLEIIAKLKELRWIHGLHIHAPEREEVALRLVKESGLKDFTPQ
VESGTGNGRGKAGSDPALQLSARELPARS
>A0A7X8IEK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MTTCRLKEMLGGNAFAVVAELTGGAGYKTEPFVRFLQDWQASDKRLPPGFHFAGITFPQN
PGGVASVDPTDALAVMHAKGLLEGLDYIPHISCKDSNTDALLSTLAGYRARGVESVLALT
GDKPLEAKGVFEVESVGLLGMIQNLNRKALLDARPGQWDRVHQFYPGAAVSPFKYTEASL
MQQYYKMEKKIAAGAKFLITQVGWDWKKSVELFGYLKDNALDIPVLGNVYWLTTRTPAPR
LMHDIKLPGCYVSDALLARLYSETLEEHIERAAQQTAMYKAIGAAGVDIGGVHDLEIFMR
ILNRAAEIGDDWPRYKDNLCWPAENAFYLYDDNGCRVSLSAPKKKCNERFFDLLHRAILD
PDHCGFRAFRATLRAFHADREGSFSNKAFNGIEKPIKYWLFECEECGDCYLPENFGYCTI
GGCEKGLDNAPCGDATVDGWCGNNLERLCIGEKIYYCAAAEPNGRLKLRRQINRPRKPAL
EHTSSIVNYLFGKDHTM
>A0A7C5MSP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MSKYQQSLLDPNTFSITWELVPGRGAFEKDQDTVLACAEKAAQGGKVHALTLTDNPSGKP
AISAEMLGVEVNKLGIEPLVHFTCKDKNRNEMESLLHAMERAGVRNILAMTGDYTYEGQR
GRARPVFDLDASQLLGIISDMNRGLEVPALRGTTVLKPTHFFAGAAVSPFKALEAEQMGQ
YYKLGKKLRAGAQFIVTQLGYDARKFQEALLMVRLLGYRDIPVIGNLYVLGAAPARLMNK
NGVPGCIVTDKLLAEIEQEAADKATAKAKRMERAAKMYAFMKGMGFAGVHIGGHGLKYED
VEFIIQRGEELVPNWLDLVHEFDYPQPNGWYYFERDPKTGLNSDKPVDRSKERPGVGLGT
RGMRLLHHSIFEPKGVFYGLMSSVSKAIDGTALEHPFTRLEHIGKQVTNECLHCGDCALF
DIAYLCPMSQCPKNQRNGPCGGSYEGWCEVYPGKQQCIYVKAYNRLKHYGQEHELGEYQV
PPCNWELFRTSSWLNYFLGRDHTAIRLGIKPPEKKG
>A0A564Q9G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Syntrophoarchaeum sp. GoM_oil|TrEMBL
MQEAFSELAKKIKAGEFVYTGELEPHNMSTEIADVVDWAKTLKGIGRITAANVTDNPQSF
SAMSSLAASYIIQRDSGLEMVYQLRTADQNRLALASVILGAAAFGLKNILALTGDHTHMG
NTPDAMPVFDLDSAQLVDLIHHMVYEGTDLSGNEVQGPRPEINVAVAGNPSQEPLEIEVL
KMERKAEVGADFIQTQVVFDLDIALTYLDSIAHIGIPSFIGIFPPRSYGQAEFFDKFVSG
VTVPPEFLKTFKDFKAIPDKADRKKKVDEFNVEYFVNFVKEIKKKKNCAGCHIMAVGYPD
VIAPIIEGAEK
>A0A2N0LDC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G3|TrEMBL
MPDNTSFNESLEKGTILGDGAMGTLLYQMAMKHDTKPVEELCLSRPDSVRLAHIEYIRSG
ATMIQTNTFAANRNKLASYGMTDSTSLINKAGIEIAKEARRLTGQQIWIAGSVGPIGRHL
EPIGTVSLVSARKFFQEQVDALAEGGADLIILETFSDLREVELAATAATSACLPFIAQMA
FGHDGLTSLGHSPGEAAAAMESMGAAVVGCNCSVGAAPMVSTVSQMLSRVSVPISAQPNA
GFPTMHQGRTVFGSSPEYMASQATRLVDAGASLVGGCCGTSPTHISAIRDSIPTRARPKK
DQLPSRRITISTREPFLSSDNEIPEPSTFSTKLKEHKKVITMEVDPPRGFRASSELSQLE
QIRNAGVLDAINIADNPRAQRRMSPLAMATLVQNRLGMETIMHLALRHRNYASLHSDLIG
AHALGIQNIFTVMGDKPRFDNYVNPYTPSNLTTTGALNLMKSFNGGLDLSGEPLESPTAF
LKGASFNPTAKDPDGEFRLLESKLEAGADFLLTQPVYDSAAVQKTAQKFGGFPIPVLIGI
LPLRSKRNAEFLQNEVPGISIPPEIMEAISSSSDPRRTGMDISRRIVTELSDTVSGVYYM
APFRRYESIIEFTESLDFA
>J2QMW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus sp. CF112|TrEMBL
MTTSKKDLRDYLQDHLLVGDGAMATQLHALGAPVGVSFEELCLSNPRVVHEVHASYYQAG
ARLLETNTFSANRDALSRYGLEHKVARINRLAVAIAREAAQDDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGADALILETFLDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYSLTDAFPQLKKAGADIIGLNCRLGPAEILRSFEGTIFPDDSLLSAFPNAGRLG
MTDGEYAFKSSPEYFAESALRLRDQGVRLIGGCCGTTPAHVKAMADALASQQPKARVNPP
VALVERPHISVQSTHEREKPSIVERVKTGTTIIVEFDPPRDLDAEQFLDGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKNRHGIDPLLHIACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMAAAVARLEKKVEAGADYIMTQPVYDVESIRQVHEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSAEALERMKKVQGPAARQEGIAIAKELLDTAVRYFNGIYLITPFNYYE
MAAELIAYVRQQSALVKTAQP
>A0A7L5YV43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MIYGQNKPVLSIELFPPKSEAGQANLDQELLSLVRHRPAFISVTYGAGGSRDKTLSLVQD
IRRRFGAAYGLEAVPHFTCVGSSRQDVRDYVDQAIAQGACNMVVLRGDPPAGATQFQPAP
DGLRHADELVAFIRAHTDQLDLAVAGYPEGHVECRHLEQDVANLKRKVDAGASVVLTQLF
YDNDDFYRFRDVASRQGITIPIIPGIMPITRFSQIQRITALCGXRIPDALAAGLMAHADG
TDDQQQVGVDYAIEQCRDLLEHGVPGLHIFTLNKGRATSRLVDALGAYFAG
>A0A7V2LB97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTENMTNGYKSGSRLERILRAGHFAVTGELGPPQGADGDVIREKAHLLKGFVDAANITDN
QTAIVRMSSIGAGTIVVQEGLEPVIQMTCRDRNRLAIQSDLMGAYACGMRNVLCLTGDHQ
SFGNHPTAKNVHDLDSLQLTQMVVKMRDEKQFQCGDEMEGIEPRFFVGAAANPFGDPFEW
RPYRLAKKVKAGADFIQTQLIFNTERFAEYMEKVRELGLHKQTYILAGIGPLKSPGMARY
MRDQVPGLDVPNIWVDRMTEATVGIDKDDKKARRDAWRREGIQIAIDLIKELKQIEGVAG
VHIMAIEWEEAVKPIVEGAELLPRPEPAPLPKSDTA
>J5IAL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp. FOBRC9|TrEMBL
MAQGRAALRDYLKTAPLIFDGGMGTYYAQKLHTRGKGVELANIETPIVVGDIHTEYLRAG
AQAIKTNTFAANRIVYQGDEELVRRIVTAGWEIAARAAAPYDAYVFADIGPVMGLPHADI
IDEYAFLADIFLALGARHFIFETNSSDEGLIETAAHIKQKCPDAFVLNSFSAYPGGYTRD
GQFVEDLVRTVAGSGYVDAVGFNCVNGTKQMKELIRHLGTRTLPLSLMPNAGHPVVVDGR
TFYESAPDYFGSSLAAIRREGVSILGGCCGTTPAHIKALCDALAAQGNIIPEEDEEAPPQ
VAELPKSPFYEALKSGAKPIAVELDPPETGSADKFMAGARELMAAGVNAITIADNPIARA
RMDAAMLAGRVHRELGIEPIPHMTCRDRNLNAIKSLLLGLSAEGVHNIITITGDPIPTAE
RDEVKSVYQFNSRKLASFITSLGSRGEVIPFHIFGALNVNAKFFGTQINLAKKKVEEGMM
GFFTQPVLSERAKENMRAVRETFPEALILGGIMPVVSERNARYMESEITGIHVEERIIDM
YRGLDRAQAEELAVRLSLEIARDIEPYIDGYYIITPFSRTALVARIVKKLKK
>A0A8I1ZX96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MTLQEVFAKKTFCLGVELVTTRGLAHHDPAAKVLRLGRDLAGRTEIDWLSITDNAGGNPA
LAAEHLGGLLRDLGAEVLIHLSAKDMNRSALEGRAWALASRGLTNVLALTGDYPVAGFRG
NARPAFDLDSVTLLAMLADMNAGMEIAAPGRAAVTLEPTAFYPGVAVSPFKAQAAELLGQ
YLKLERKIVHGARFIITQVGYDARKWDELRLHLAERGHALPCIGYVYLLGKGVARIFHRN
QIPGCVVSDELLALVERQAAGPDRGKSFFIELAAKQAAILRGMGYRGAYLGGLSSPAQLD
AILERLGSFSPDDWRLFAKELQFPAPKEFYMYARHPETGLADAAARKPVPRAPAGALERL
AFAFNQVFHRLVFASTAPLFGPAARVYRALEKRPRLAASARDIENLIKAVLFGCRGCGDC
SLPETTYICPEFACPKRQRNGPCGGSFLGQCEAEDRDCIWVRAFRRCGGAEQFAALFQAA
PTFVDDALRTSSSWANAFLGRDHHRYEKGVKHGDSGTHADR
>A0A7V9Q4G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrinomonadaceae bacterium|TrEMBL
MASFKDLLESDHVAVFDGAMGTMLYAKGVYINRSYDELNLTQPDLVREVHEEYARAGAEV
LQTNTFGATAHHLQQYSLEGSLRAINIAAARLAREAAGRRCFVSGAVGPLGLRIEPYGPT
SFDEAKDMFREQVSALLEGGVDLFVLETFSDISEIRQAIRAVRELCDLPVVAQMTILTDG
NTSFGTTPEVFTARLDEWGADVVGLNCGVGPAILLSGVEKMRPLTNRKIIVQPNAGLPRD
VQGRQFYMCSPEYMAKYSKRLIQAGVKFIGGCCGTTPAHIKLISDAVRAISPRLHRAVPE
VTRPARVEELTPADIQVVPLEERSRWGSKLVAGEFVTTVEVLPPKGCDAAKTLEQIRLLK
DAGVDAVNIPDGPRAQTRMSAQATAILVEREVGLEAVLHYCCRDRNLLGMMSDLLGAAAL
GLRNLLLITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGIPTSFCVGV
GVNPGAINLDEEIRRFEYKVEAGAEFAITQPVFDVEQLRDFLKRIEHVRIPVVAGIWPLV
SYRNAEFLHNEVPGVRVTASIMERMRIASEKSKEAARDEGLRIARESLIEVRDLIQGVQV
SAPFNNVRYALEVFDVLEDFAARREAKAVTNN
>A0A7C8ES25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MKSGSRLEKVLTAGKFAVTCELGPPKNSNPQIIKKKAGYCAGKVDGVNITDNQTAIVRMS
SIASGVIAMSCGLEPIMQMVCRDRNRIAMQSDILGAAGLGIRNILCLSGDHQKLGNHPEA
KNVFDIDSIQLIAMVRKMRDDKQFLSGDPIKEHEPRLFIGAVANPFAGPLELRVMRLAKK
IQAGADFIQTQCVFDIDRFGEWTELVTEAGLHSKVYILVGLTPVRSHKALLYMKSNVAGM
SIPNELVSRMESANDAGEEGVKICLEMIEKVRKMEGIAGIHLMPIGWESITPVILERAGL
LPRPEV
>A0A7C6F8E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
GGKPERLTPTRFFIGCAVSPFKRYERELVPQYFKLIRKIATGAQWVITQLGYDMRKYHEV
KLFLAARGMPQIPIIGNVYLLTRTIARLFHTGKLPGCVVSEELMALCDKYGAGPDRGRKF
FIELAAKQLAVLKGLGFSAGYLGGLNKPETFGEIMEQLTTFSEDDWKLFLREIQFALPDE
FFFFEHDPETGMSSPDRINRQYLESLKRPGRSRHVTLGYRLSRLVHRLLFTRDRGLWGLA
RRLYARWARKPQLPITARTLYKIEQFSKFMMYGCQDCGDCSLPDCAYVCPKRWCSKCGRN
GPCGGSADGRCELQDKECLWAIVYERLKAYGETESMLQGPPVVYNAELAHTSSWANTYLD
RDHHRPRESNPPDKDQT
>A0A4Q3U1E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
DIDTFKSDFCIGVAGYPEKHFEAPNLNADFKFLKKKVDMGAEFIVTQMFFDNQKYFDFVK
KCRENGINVPIIPGLKPISTLSQLTVLPKIFHIDLPEELTDALAHAKSNAEAKEIGTAAM
IKQCKELIEFGAPVLHFYTMGRPEQTKQIARAIF
>A0A5C9C2I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSIRDHYGPGKFGLSIEIFPPKTPAGNAALFESLDRLSAFQPSFVSCTYGAGGSTSKRTV
ELCVEIQKRYGIPATSHFTCVGATRDELIDWLKFARQNGIGNIMALRGDPPAGQTDFQPV
AGGLRYANELVALIREHFADMGIGVGGYPEKHPEAPDAETDLTNLKRKVDAGADAIFTQL
FFVNENFFRFCDRCEAAGIRIPIVPGIMPVTEFARIKRITSLCGAVFPTELASRLEAVQT
DEAAQFQIGVEWAIRQCRELVSRGVPGLHFYALNKSPACEMILNAIRG
>A0A1X4MWP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira sp. MCCC 1A03138|TrEMBL
MRVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGSTRDRTHSSVTRIQGETG
IPAAAHLTCVGHTKEEIEGIARNYWDEGIRSIVALRGDLPDAGDKYVPTPGGYPYAVDLV
EGLKRIADFDISVSAYPETHPDAPNADFEIDYLKHKIDAGANRAITQFFFDNEVFLRFRD
KCVAAGITAPIVPGILPVTNFGSLLKFADMCGASVPKRLHWRFEDLDEDPDTRRMVAFHE
AISQVEGLMAEGVADFHFYTLNRAELTYAICHALGIRGVAQAAA
>A0A367Z9X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MADQRASNGYVSGSNLERVLKSGNFAVTAELGPPQSADAEVIRKKAALLRGYCDAVNITD
NQTAIVRMSSIGAGAILVSEGLEPVIQMTCRDRNRLAIQSDLLGAYALGMRNILCLTGDH
QTFGNHPQAKNVFDIDSIQLIQIVKNLRDEHVFQCGDPLKGLEPRFFIGAAESPFAHPIE
FRPYRLGKKIKAGANFIQTQLVFDIPAFEAFMEKVRALGLHQQAYILAGVGPLKSPAMAK
YMKESVPGILIPPELIQRLEDAGLPWAGKSKDELTKEEKKARSEAWKQTGIDICIELIQK
IMQIEGVAGVHIMAIEWEEAVEPIVKGAGLYPRPVVEPLVA
>A0A271J4C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivirga marina|TrEMBL
MKVIEHYDRADGPLFSYEIIPPTRGSSVGDVLGVVEQLKPYDPPFIDVTSHSAEAVYEEM
GDGTIRKRVKRKRPGTLGLCAAIQYRFGIDAVPHILCRGFTQEETEDALIELNYLGIHNL
LAVRGDDTGVQKLVRPGRQQNAYACDLVAQIRAMNEGRYLEDLLDAAPSDFCIGVGGYPE
KHADAPNMTWDVLNLKRKVDAGADYVVSQMFFDNRHYLGWIEKCRDVGIDVPIVPGLKIL
TSKRQLQSLPRSFHTEIPEALAAEVEAAKPEHVAEVGVEWARKQAEELLEAGVPGIHFYI
MSTAKHVVRVAEPLRKLVG
>A0A433F2N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. KS69|TrEMBL
MVSYAQGVDALNQSLSELRDIDVSFEFFPPKSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELRQIAQDYWDSGIRRIVALRGDLP
PGVKDTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIS
QFFFDTSVFLRFRDRAAAAGIDLDLVPGILPVTNYQTLVKFAGFTNVHVPGFLHKMFDGL
DDDDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRAG
>A0A1G7TP93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limimonas halophila|TrEMBL
MPWHRVRDLVSIAREWRAGPTPRTDHGPVPTTLEEGVTSPMSSARDAANADRPSDRSEQI
RQFVRGWSIETTPKGDEKVNDYNDHLHPGTKVAVTFLPGSDYRDTVRVAARLRREGFEPA
PHIAARSLKNKGELEDFLARLRGEADVRQVVALAGAVDNPVGEFSDSMQLLETGLFDKQG
IEKIGVAGHPEGSPDISDEAIMRALKWKNGFAERTDAHVYIVTQFIFEAQPVIEWDRKIQ
AEGNTLPIHIGVPGLATIKTLLNYARWAGIGNSIQFLTRRAKNVSKLMSTNAPDELVSDL
AKYWAEDPNCGIERMHIYPLGGLRKSAAWANAVVDGDFQFKRDGRGFTVNRDIG
>A0A367AIR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. TF02A-26|TrEMBL
MTRTVRELLAEGTPTWSFEFFPPKTPEGEQQLWTALRELERLRPSFVSVTYGAGGSTREG
TVSVTERIATETTMTPLAHLTAVDHSTAELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WIAHPEGLSYAAELVELIRSMGDFSVGVAAFPERHPRSPDFDTDVEMFVAKCRAGADYAI
TQMFFRTEDYLRMRDRVAAAGCDVPIIAGVMPVTNARQIARIVQLSGQAFPEELAARFAE
LDGDRPEDKAAVRAYGVEVATAMCRTLLDEGVPGIHFITMNRSTATREVYGNLVPVAPLP
PSLDAVS
>A0A4Q3RK40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIDHIRQAKDTLVSFEILPPLKGKTINSIYEHLDPLMEFKPSFINVTYHRSEHVFKKK
ADGTFDKVEVRKRPGTVGICAAIMNYYHVDAVPHLICGGFNKRETEDALIDLNFIGVDNV
LILRGDAAKNETLFEPDPDGHRYAIDLLKQVVNLNNGIYLEEDILDGFRTKFSIGVAGYP
EKHFEAPNLDTDLDYLKEKVEAGA
>A0A522R8P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTDHLKDAKDTIISFEILPPQKGKGIESIYNHLDPLMEFKPAFINVTYHRSEYIFKKK
TDGAFEKVEIRKRPGTVGICAAIMNHYKIDAVPHLICGGFSKEETENALIDLNFLGIDNV
LVLRGDAPKNETFFSPEPDGHHYALELLNQVVNMNHGIYIEDDLTDGLKTNFCIGVAGYP
EKHFEAPNMETDMHYLKKKVEHGAEYITTQMFFNNDKFFEFEQCCRKNGITVPIIPGLKP
ITTKRQLTVLPHIFHIDIPSELSESIIACKKDEDVAKIGKEWLISQCKSLKAHGVPALHF
YTMGRTHIMYEVVKGIM
>A0A2E8M7Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MEILSLLKAPRPTLSFEFFPPKDDAGADDLLGIVDDLGKLDPAFVSVTYGAGGTTRGRTR
SLVQRIMKETSVPTVPHLTCIGHSEDEISEILHHYSKDHVSTILALRGDPPRNEPNYDRR
KDDFKFAADLVKFIKNHNHPIEIGVAGFPEGHPATQNRLKEMEYFKAKVDEGADYICTQL
FFDNHDFLDYRDRCALEGIDLPIVAGIMPITTISGMKRMAELAEGSRFPATLLKALYTAG
NDAKAIRQAGIQYAIHQCQELIDEGVSGLHLYTLNKSNATLTIANSLEF
>A0A4Q5STE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTEHLQKSEGRTLVSFEILPPLKGKGINALWEHLDPLMEYHPSFINVTYHRSETMFKR
KADGTFDKVEVRKRPGTVGICAALQNRYKVDAVAHLICGGFSKQETEDALIDLHFLGIDN
VLVLRGDAPKNEAMFEPEPGGHAYAIDLLHQVQQMNNGLYLEEDLKNAVKTDFCIGVAGY
PEKHFESPNLRADLAWVKAKVDAGACYITTQMFFDNQKYFDFVKACRDAGIHVPIIPGLK
PLTSRKQLSIIPRTFHVDIPEDLSNAVLAAKTDADVERIGGEWLLQQSKDLKAAGVPVLH
YYTLGKPKVIADVCREIA
>A0A3D5Q3U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp|TrEMBL
MESQKQFKRRFSFEFFPPKTDKGKEKLQKVRDRLAEVNPDFFSVTFGAGGSTRDRTIETV
LGLHKQGISTAPHLSCVGGTRDAIGELLDVYQKSGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIRERTGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYF
>A0A3N1KND9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas rhizophila|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAAKLKVFAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFDAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASDLISFI
RAEHGDAFRIEVGAYPETHPQANDALLDLKHFKTKIDAGADAAITQYFFNADAYFHFVDA
VRKLGVTVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDADSVRAFGAEVV
ASLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLRG
>A0A1Y4GHY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cloacibacillus sp. An23|TrEMBL
MKNFFKLDKPTFSFEIFPPKGKGDLTQIFNTVDALASLDPDLISVTYGAGGSSRENTAEI
ASRIQRDYAIPALAHLTCIGSTRGEMRAILDTLRDKGIQNILAMRGDIVNEGTKDFAHAS
DLIKFIKENYGFRIFAACYPEKHIEAYSMEEDLKYLKAKCECGVDALISQLFFDNEHFYE
FRDKARAMGITQRIEAGIMPITSPSQINKMVTMCGASVPAGVQKIIRAYGHNAMAMREAG
TAYATAQIIDLLASGVDGIHLYTMNQPEIAKRICENIRGVLYSLRVKRG
>A3XBM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseobacter sp. MED193|TrEMBL
MTSPEISFEFFPPQSLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRDLTRDAVKTLHG
SSGLNVAAHLTCVDASRAETMEIAENFAKVGVTEIVALRGDPPKGSGKFVPHPEGFGNSV
ELIEALAATGKFSLRVGAYPDPHPEAENAQADVDWLKRKLDAGADEALTQFFFEAETFLR
FRDACAKAGIDGDKLVPGILPIENWKGARNFAKRCGTVIPAWVDDAFEKASRDDREDLLA
TAICSELCSDLLDEGVKKLHFYTLNRPELTRDVCFALGLTPNVSLENVA
>A0A3B9G587|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MAILSSLRASRPTLSFEFFPPKNNLGSEELLETVNELGKLDPAFVSVTYGAGGTTRERTR
EVVQRIIQDTNVPTIPHLTCVGHTKSEISEILSQYSADQVGTILALRGDPPRDQPNYDRE
GDDFKFAGDLVAFVKENSNEFEVGVAGFPEGHPETQNRLTEMDYFKSKIDQGADYICTQL
FFDNHDFFDYRERCNLVGVDLPIVAGIMPITTISSMKRMADLAAGSRFPAKLLKRLSVAD
GDAAAIRQAGIDHAIEQCQELIEQNVSGLHLYTLNKSSATREIANALTF
>A0A366IJD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium celere|TrEMBL
MTTPAALKLLDNFSLEMTGKDIPGLEEASRAIPQGTKINVTFLGNEDLEMRVAAAKRVKE
LGFVPVPHISARRLQSQQQLEEFLAALHGVDATDHVFCVGGDPATPEGPYPDSLSVIRSG
VLQQYGVKEVSIAGYPEGHPDISAEVLWQHLEDKSAALAEQGLDAVVLTQFAFDAEAVLK
WVLEVRDRGIDSEIRVGTPGPAGIKRLLGYARRFGVGTSAGIVKKYGFSLTNLMGTAGPD
RFVGELGDLLAADARSGRVRTHFYTFGGLLATAEWAQTFGTGH
>A0A1Q6FZG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. 58_9_plus|TrEMBL
MSVASFLAEPHTTAFSFEVLPPLRGRSIEQLFASIDRLMPFNPAYINITTHRTEVVYRQI
SDGVFQRTAQRTRPGSVAVAAALKGRYGIPTVPHVICSGFTRAELENELIDLSYLGITDL
LVLRGDRARGENRFIPTEGGHEHAAQLCRQVEEFNGGRMIDGEEFTPLEHPFTFGVAGYP
EKHDEAMNLDTDIEYLKAKIDAGARYVVTQMFFDNRRYFDFVARCRAAGITVPIIPGLKP
LTSLTQQALLPKTFHIDLPMELAEELRRCRSNDDVKALGVEWAVAQARELKAANVPSIHF
YSMNATASVETIARQVY
>A0A5C8BZ66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicycliphilus sp|TrEMBL
MSLPLSFEFFPAKTPEGADKLRTVRQQLYARAPQFCSVTYGAGGSTQAGTFAAVREILAE
GVQAASHFSCIGATKDSVRAQLAELKAMGVKRLVALRGDLPSGYGLGGEFHYASDLVAFI
RAETGDDFHIEVAAYPEMHPQARSPEADLQAFATKVRAGADSAITQYFFNADAYSRFVDE
SRRLGLDLPIVPGIMPITGSTQLMRFSDACGAEIPRWIRLRLSGFGDDSASIRAFGLDVV
SRLCEQLVAAGAPGLHFYTMNQSTATLAICQRLGR
>A0A2D6A8U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MVRIADLFAAYEAEDRRVVSFEFFPPKTDEAVEELFRVARDELAPLAPSFISVTYGAGGS
TRRKTLELVSRIKNDIGLEAMAHLTCVGHSRDELAEIIDGIVAAGIENVLALRGDPPTGE
TEFRPAPDGFRYGSELIAFIRDLGAPLCLAAACYPEKHPEAATAEQDLANLKAKVDAGAD
YLVTQLFFNNADFFAFQERARAIGIAVPIVPGIMPITNYKQVRRFTRMCGTHIPVKLTDR
LKAAKNDRAAVTSIGISYAIDQCRELLANDVPGLHFYTLNKSSATRAILSRLRHAR
>A0A542Y4Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter komagatae|TrEMBL
MNATLLTGSAPTRARFSFEVFPARSGAAALALGNSVQHLSAVGPDFISVTYGANGSNRDA
SLDLLAYLRDHTDALPLAHLTTVRESREAIRDTIHRIMDAGIHDFLALRGDPPQGLDESA
PEVAGSLSALELTELIAEARAERPAFTSVGRTAVAAYPNGHPLSRGRSADIDWLLAKEAA
GAQFAITQLFFEADEYLSFADAAREAGLGMPLLPGLMPVSTSGQLRKVASLAGRPAPPAL
ERALEEAGGYAPELGVEHTIGLARELLEGGAPSIHLYTFNRHEQVLAVLADLDLLPAR
>A0A3M1I0T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MNGNGYLSGSNLERVLRAGHFAVTAELGPPQSADAEVIRKKAALLKGYCDAVNITDNQTA
IVRMSSIGSAAIVLQEGLEPVIQMTCRDRNRLAMQSDLLGAYAIGIRNILCLSGDHQTFG
NHPGSKNVFDMDSIQMVKMVTDMRDRRVFQNGEEIKGQEPRFFVGAAASPFAHPLEFRPY
RLAKKVKAGANFIQTQLIYDIEAFAKFMEKVRELGLHEQTYILAGVGPLKSPGMARYMRD
NVPGILVPDEIIERMKKAGAPWAGKKKDELTKEEKKARSKAWREEGIKVCIDLIKQLREI
EGVAGVHIMAIEWEEAVKPIVEGAGLYPRPKVPAPEPQAA
>A0A372ZTC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora xanthocidica|TrEMBL
MALGIASTRTDRALTVRELLAAGKRSFSFEFMPPRTEAGEQKLWDAIRRLEPLDPNFVCM
TYGAGGSSRERTVNMVGRIATETTLTPVAHLTAVDHSIAELRNIIGQYADQGVRNVLAVR
GDPPGDPMGEWVKHPEGVTYAYELVELIKGIGDFCVGVAASPNMHPRSTDWDEDIRHFVA
KIRSGADYAITQMFFEVDDYLRLRDRVAAVGCETPIIPEIMPVTNAKQLERFPQLSGSAF
PVDLEARLRAAIDDPAALRAIGMEHATAMAERLLAEGAPGLHFITLNHSTATLEIYQNLG
LHQR
>L0R852|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maridesulfovibrio hydrothermalis AM13 = DSM 14728|TrEMBL
MQVAKGIKESGQFFSFEFFPPKEKTTWPAFMEKAERLANLNPLFASVTYGAGGTSHDNSL
EICTVLKKEMGIDILAHLTCVGASEKSIDEFVEQLGKVEVTDILALGGDGKSDEQESQSR
FYHAKDLVEYVNNKFSSVGIGVAGYPGGHPDCPSIAHDLKFHSDKLSKGADFTMTQLFFD
NRQYFDYVDRLNGMNATRPVIPGVLPIQSLASLRRIMSLCGAAIPGDLYCGVEDAFNSGG
DEAVMDFGFEFARKQIAGLLDNGAPGVHIYTLNRAAMCERLISALKQDGYFS
>A0A7G7WGW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus vulgaris|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTEEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASREELQHIAQDYWQSGIRHIVALRGD
LPDNTQKPDMYATDLVHLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMFD
GLDNDPETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPELVQA
>A0A523REE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MTKRPAYSNLVKTMREGKFLFTGELEPKKMIDLSSILHSAEEMKKTGKIVAANVTDGPQG
DAYTCSMVPCYLVQEKVGLEAIWQMTVRDRNRIALFGDILGGAILGLKNILALTGDHTAL
GDHQNARPVFDLDSTQLIDLVSKMVDDGTDLKGNEIEGGKIEMNVGCAANPNSNPREPEI
LKVGRKVEVGADFIQTQTSFDIDDAKEFLKELEKFNVPVLLGLFPIKNYGIAWYFNEYIP
GVSVPKDLLKALKTAKKEYKDDKKKRNEVIDKINIDFYEPFIKEIQKTTKAAGIHCMAVH
YERLFEPLLKNF
>A0A524FKQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MKNKLRRRKNKMAKRPAYSKLCKAIEAGHFVFTGELEPKKILDLDEIFHSAGEMKKTGKI
IAANVTDGPQGDAYMSSLAPSYLIQENVGIEAVWQVTVRDRNRVALFGDVVAGAVLGLKN
ILTLTGDHTALGDHKRGRAVYDIDSTQFCEMLSTMIDKGTDYEGNELLGGKIEMNFGCVA
NPNSNPREPEIFKVGRKVEQGVDFIQTQTAFEIDQAKEFLKELEQFNVPVLLGVFPLKSY
GIAWYFDNYIPGVSVPKDLLKALKKAEKDNKGNKQGKYDALDKINIEFFEPFIKEIKKTT
KAAGIHCMAVEYERLFEPLLKDYPKYAEKIS
>A0A7W7U7I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces nymphaeiformis|TrEMBL
MNPESPTYSFEFFPPKTDRGEQTLWDAIRRVEALRPDFVSVTYGAGGSSRDRTIDVTKRI
VTETTLRPVAHLTAVGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRGAWTPHPQGFT
YASELVELVRSLGEFRIGVAAFPEGHPRSFDAGSDLAHFVAKCRAGADYAITQMFFDPED
YLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAKDDPAAAY
RIGVEHATQMGLRLLDEGAPGLHYITLNKSTAALEIHRTILSARRVAAHV
>A0A8J2VZV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agaricicola taiwanensis|TrEMBL
MTAMEPLRLSRRQDASPIRVSFEFFPPKTEEMEKTLWNSIGRLAPLSPSFVSVTYGAGGS
TRERTHQTVTRLVRETDVKPAAHLTCVAASKAEVDDVIRSYAAAGVRHIVALRGDPVGGI
GTTYEPHPEGYAQSNDLVAAIRRIGDFEVSVSGYPEGHPESASIDADIEILKRKVDAGAT
RAITQFFFDNDIFERYIEKVRAAGINVPVLPGIVPVHNFKQVSNFAAKTGASVPAWLAAR
FEGLDNDPATRQLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRPKLAE
AA
>A0A847FZR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolinea sp|TrEMBL
MHLSEILKENKVHFSFEFFPPKTEDASCRLLETITKLSPIRPSFVSVTYGAGGSTNELTQ
NLVIRLRQETPLNVVAHLTAVGASRDDIRAQLEKYAAAGIHNVVALRGDPPRGNPDFTPA
PNGFAHAVDMVSYIKKHFPHFGVSVAGFPEGHPESPNRLQELDYLKAKVDAGADCITTQL
FFDNRDFYDFCERCEIAGIKVPILAGIMPVTSVSGLKRMSELAQRARIPAKLLRAVLRAQ
SDESVEKVGVHWSTQQVFDLYDHNVSGIHFYTLNHSKATLKIYETLGMSLGEAWHVPNGN
GGCSATG
>A0A829BC93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae PCS70012|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEEHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A1A8QUK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius rachovii|TrEMBL
MNVAAPFTVMVNQVQRVDGSWLSCKSDSSGTSNSGGESSKESSRCSTPVLDAVRSDRLRD
KMRRRMESGDQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKET
SSMMIASTAVNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEE
EEGGFNYAVDLVKHIRSEFDDYFDVCVAGYPTGHPEAESYADDLRHLKEKVDAGADFIIT
QLFFRADTFLTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPI
KDNDAAIRNYGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPL
PWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFY
LKSKSSKEALLQMWGEELKREESVFEVFTCYITGQLNRNGHKVMCLPWNDEPLAPETNLL
KDELEKVNRRGVLTINSQPNINGKPSTDAVVGWGPAGGYVFQKAYLEFFTSSENVNALLK
VLKKYEPRVNYHIVNVHGRNLTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEA
FALWIEQWAKLYEDESPSRIIIKYIHDNYFLVNLVDNDFPLESCLWRVLDDMFELLDAPL
ETLADGMSGDGSHGNGTLAE
>A0A161YHQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium magnum DSM 2767|TrEMBL
MFIKDIISSKKLSISFEVFPPKNDMPLDGVYKTIGELAELNPDFISVTYGAGGSSKGRTI
EIASTIKNKYGIEAVAHLTCATSTKEEINNILSELKDNGIENILALRGDIPDGFKISDNL
NYKYAKDLIGEISERKKFSISAAAYPEGHTECSSLEDDIRHLKEKVDCGAEVLITQLFFD
NNKFYEFKEKLYKHNINVPVITGIMPVVNRNIIERIGVLSGAFIPQKLKNIIDKYENSPE
ALVDAVIAYSTEQISDLIVNGVDGVHIYAMNKSAVAKRIMKNIKEIRKAINS
>A0A4P5U0W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MRFEDEPVPGYPLPILPGHTSPGRLERVLRSGAFAVTAELDPPDSADPQDVYRRARVFDA
YVDAINATDGSGANCHMSSLAVCALLTRVGYAPVMQISCRDKNRIAVQGDILGGAAMGVA
NMLCLTGDGVQAGDHPQAKPVFDLDCMSLLEIGRTMRDEHRFQSGRKLTFSPRVFFGAAA
NPFGLPVHWRAQRLAKKVAAGAQFIQTQYCYDLPRLKSFMQEVEDLGLLEQVFILVGVGP
LRSAKTAEWMRTNVPGVHIPDAVIKRLAGAEKQALEGRQICIEMIQQVRQIRGVAGVHVM
AYRQEDSVAEIVERSGVLEGRVPWYPGRDAEIQTLKETA
>Q6CZA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWQSGIRHIVALRGD
LPPEGGKPEMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSVFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A1M7Z408|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus zhangzhouensis|TrEMBL
MKITEHLSNADKTLFSFEILPPLKGQSLKDLLEGIEPLMEFKPPFVDVTYHREEFIYKKH
PNGLLEKISTKKRPGTVGICAAIMNKFHIDAVPHLLCGGFNKEETENALIDLNFIGVDNV
LALRGDAPKTEGKFVPELDGHHYASELVEQIVGMNNGKYLHEETETSFHTDFCVGVAGYP
EKHFEAPSMKFDLKYLKEKVDKGAEYIVTQMFFDNQKYFEFVDKVREAGLDVPVIPGIKP
ITSVNQITMLPRTFFLDLPDPLMDELEKCKTNAEVKEVGIEWAIQQCKELVKANVPSLHF
YTMSKASATYAIAKEVF
>A0A5C3LAC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprinopsis marcescibilis|TrEMBL
MKISQKIQASAKDDKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGLETCMHLTCTNMPKEKVDIALRDAKESGCRNILALRGDPPMGKDE
WQAVEGGFVHGIDLVRHIRKNYGDYFDIAVAGFPQHMLLPPEERDNEIRWLKEKIDAGVN
FIFTQMFFDVDVFISWVKAIRAAGITIPIVPGIMPIQTWNGFRKSTSLAGAEIPQFLLDA
LEPVKNDDEKVREIGTKLVAEMCKKILNSGLGIRGLHFYTMNLEKGTKMLLEELNLIPRI
ETIKPLPWRQSLTPSRRNETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGEVD
GYGIAIKQTKENALKLWDHPTTLADISALFARFCKGELTALPWSDQAPSSETSVIAEHLV
KMNDLGFLTINSQPAVNGARSDDKTFGWGPSNGYVYQKAYLEFFVDPELLTLLLKHIERD
SNITYYVTNKRGDLRTNTHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGHQ
WAKLYEHESPSQKLIFDIMENYSLVNVVHNDFLNPDAIFQPFWKAGAEWQALKSGAPAVN
GH
>A0A370DDI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|endosymbiont of Galathealinum brachiosum|TrEMBL
METQKKLDKNFSCEFFPPKTDKGMENLLSTAETLKNEINPEFFSVTFGAGGSTRETTFNA
VTKIQQSTGCDVAPHLSCIGSSKQQLKDILDDYKNQGIKRIVTLRGDMPSGTVSQSDFNY
ANELVGFIRDNYNDQFHIEVAAYPETHPQAENANQDMLNFKNKVLSGADSAITQYFYNID
SYFYFIDNCEKAGLDLPIVPGIMPITNYSNLARFSDMCGAEIPRWLRRKLESYADDTDSI
KEFGADFVSSMCQKLLEMGAPGLHFYSMNQSEATLKIWNNLKL
>A0A7V2SNU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MLEQKLKNGDFVITAEIVPPLSSHRDDLLKRVAPLAGLADAVNVTDGAGARLAMSSLSAS
AILVSAGFEPVLQMTCRDRNRIGLASDLLGAGAQGVENLLVLRGDNPAAGDMPEAKAVFD
LESSELIAMASDMQKVLGNDGLEVTAPPELFVGCADLPHDPAPDWKPQALRAKIAAGAQF
AQTQFCFDVEIAKRYFDHLEKSGITDQLRFIVGIGPLLSLKQAVYMNEKLFGVNVPDHIL
ARMEAAEDQKAEGQKICVEIATALKEIAGVSGVHIMAPGQNGNALARTIRSIRAS
>A0A8I1P539|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MLQSRLSRRPDMGDRVRVSFEFFPPKNDEMETRLWETVKRLEPFAPRFVSVTYGAGGSTR
ERTQRTVTRIKAETSLTPAAHMTCVDASRGEVDAVIADFARSGIRNFVALRGDPREGVGA
SYRPHDDGYANGAELVAALRRAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDAGATRA
ITQFFFDNDTYERYVERVRRAGILVPIVPGVLPIHNFAQVANFASRCGAHVPAWLARRFE
GLAGDPQTHMLVAAAVAAEQVHDLVERGVGDFHFYTMNRADLPVAICHMIGLRPAEQRQA
LSAA
>A0A7V5LE46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MDFRRRLKGPPILADGAMGTELYARGVYVNRCFDELNLSRMDLVSRIHSDYLRAGSELIE
TNTFGANRYKLAPHGFGDRVERINELGAKIARRAVEKCAVNAYVAGSVGPLGKRLAPLGK
IQVSDARGAFVEQARGLVGGGVDLIMIETMVDPVELRIAVEAVREVSDIPIVAQFTLKDW
NETVYGATLEKITADIEALDVDVIGINCSIGPSKLLEAAKRLMELTDKPVAVQPNAGELE
WVENRVICRTTPEYFAEYARRMALSGISIIGGCCGTTPGHIKAIDAALRSVSPKSSKETV
TVRAERTEPETEAKEPPPYRQLSKMAAALDDGRFVISVEINPPRSPAVRRIIDKSVELKE
SGVDLVNVPDGPRASARLSAMVLAHEIHGRAGIETILHYTCRDRNILGMQSDLLGAESLG
IDNILCVTGDPPKLGDYPMATAVFDVDSIGLLRIADNLNHSLDLAGNPIPHGTAFNLGCG
VNPGALDPELEIDRLHRKIENGARFVMTQPVFDEELFFNFMERVNLRKV
>A0A7X6HDQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter mobilis|TrEMBL
MTFSQRAAAPPSLSYELYPPARPEAEASVLSAIEELEATNPDYVSVTYSGTPARRRASIQ
LIEHLMRNTRLRPLAHLTCVGETRDSLDLLVRQIVGLGVRGVLAMRGDLPQDPEASRGEL
PFARYLVELIREVEARHGATLAGGRLAVGVAAYPNRHPESPSFQHDVEVLVSKERSGADF
AITQVYFDPAHYVRLVAAARAAGVTIPIIPGVIPMSSVRRLERLAVMTGVRPDAALLHRL
ETASDDAERQRIGVKAAAELARAAFDAGAPGLHLYTFNDPHASIEVIEQVGLPAARTLST
PVPA
>A0A7C6ETX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
PLNINITYHQSEVEYRRLPGGLLEKRIIRKRPGTIGIAAAIMNKYQVMVVPHLICGGFTR
EETEDALIDLHFLGIRNILALRGDPQKGEKYFIPEEGGHAHTVTLVEQIINMNRGIYLDE
NLKNAIPTDFCVGVAGYPEKHFEAPNMETDLRHLKAKIDAGAEYVVTQMFFDNRKYFDFV
ERCHKAGINVPIIPGIKPVNTLRDIELLPRAFHIDLPEELVHEVQKCKTNQEAKEVGIEF
CIAQSKELVRAGVPAIHYYTIGISDNIRKIASAVF
>A0A838RLX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ardenticatenales bacterium|TrEMBL
MGTELAATQGLSDSTSAEALNLTAPDAVRSVHLAYVAAGADILQTNTYQATRVALMPQGL
DVDAVNRAAVGHARAVSANASRQVWVAGSIGPLGEKRYIFDILSDQQMEEVYAEQILVLA
EAGVDLLVAETMGDYREVIAATRAARAVAPQIPLVVQLEVFDGQTLGGRIDLATVVKQIE
AIGVDAIGANCRVGPEMMQRTARRLLELTELPISLQPNAGTIGIDYTGRMHTFGQPEDFA
SFAQWALSRGVTLIGSCCHSTPRHTMAMRAALDRAKDIEVLPRPQRSRSRLERRLKRGEF
VICVEIDPPSDDEYQRNPGVLQHKIDGARYLEQRHHVDVITIADHTMGKPWLDPFPFAEV
IRPHLRKADLLLHYSCRNKAETDITGNFASYKLYGYNNILIITGDPPADPTEECFFRFSS
IKLLKRISEDHPDHFFLGCAFDHTRGLHRGEAGLEGEVRRLEKKVAAGARLALTQPIFLD
RIDQLYEKSKHLPIPILPGIMPIFSLQHAETVSQFGGIVIPEYVKERLASAGTSRAAKTR
VAVEIAGEVAQRAKELGFPGIYLISSFNRFDVIAGTLKYVNEPQPVLALGD
>A0A8B8U931|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Camelus ferus|TrEMBL
MDRPKPRVPAVGPCCPSRGMRASEAGSARFSVPPCISRNSAMVNEPRGNGGPNPRSEGSS
SGSESSKESSRCSTPGLDPERHEKLKEKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYAADLVKHIRGEFGDYFDICVAGYPKG
HPDAESFEADLMHLKEKVAAGADFIITQLFFEADTFFRFFKACSEMGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCRELLESGLVPGLHF
YTLNREVATMEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGKELTSEESVFEVFVRYLS
GEPNQDGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETTEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGKLYEEESPSRMIIQHIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRAPQNEREMEAP
>A0A7V1IEU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
TLYGRTPEQIAGALASEPVEVIGLNCSTGPQVILEGLQQMREVTDKPLAAFANAGEPKMV
EGRLLYLATPEYFAEYTKRLMQHGVRLIGGCCGTTPQHIRMMAAAIRALQPVSAPAQVLV
SPRRKKKSAPARRMKLAPRGERSPLGRLLDEGAFPVSCELNPPRTPATGRILRQVRMLQA
AGVNVVNLPDGPRASARMSPMALAHIIAGETGMDTILHYTCRDRNILGMQSDLLGAEALG
LKNILAVTGDPPKLGDYPMATAVFDVDAIGLLRIADNLNHGLDLAGNPIPRATTFFLGAG
FNPGAIDLALEVDRLHQKIEAGAEYILTQPMFDQEKLLVAIEKAGGVKVPIIAGILPLGS
YRNALFFHNEVPGMSVPEPIQERMRLASEKGKEHAQAEGVAIAREALGAVREYVQGAYIM
PPFGKVEMAIETAAVLPGRKDLAQVLLEVEENGGEE
>A0A0H3FLZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella aerogenes (strain ATCC 13048 / DSM 30053 / CCUG 1429 / JCM 1235 / KCTC 2190 / NBRC 13534 / NCIMB 10102 / NCTC 10006 / CDC 819-56)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7C5KN29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MVSWLQNGRQEIMTDLKNKLANDEFVITAEIVPPLSADAEALRGKAAVLAGLTDAINVTD
GAGARPAMSCLAACIALRNDGHEPVLQMTCRDRNRIGLASDLLGAAAFGVTNVLVLHGDD
PAKGDMPDAKPVFDLDSKGLLRLARTMRDE
>A0A3D4M9A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKIVDHIQSAKRTLFSFEILPPLKGNSIESLYSGIDPLMEFDPKFIDVTYHREEYVLRER
HDGGFDKVATRKRPGTVGICAAIMNKYHVDAVPHLICGGFTREETENALIDLAFLGIDNV
LALRGDNLSGDSMFKPEDDGNKNALDLVNQVREMNQGIYLDQELKNATPTNFCIGVAGYP
EKHQDAPNLRSDINFLKKKVDAGAEFLVTQMFFDNKKYFEFVALCRDNGITVPIIPGLKP
FATQKQLYALPKIFHIDLPDDLVLAVEKAKNNDQVKQIGIDWCIQQSRELRDAGVPVLHY
YTMGKSEATFAVAKEVF
>R8WP67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. KTE151|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIAQDYWHNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A4V1SWI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MTAIPSENRASRQFGDSRPPHQVSFEFFPPKTDAMEERFWDSVHKLAPLNPRFVSVTYGA
GGSTRERTLRMVSQVKSTTGVDAAAHLTCVGASRDEVDAVVRGYKEAGITRIVALRGDPA
EGIGQPFVPHPEGYTSAADLVAGITRIGDFDISVAAYPDKHPQSPDWDTEIANLKRKFDA
GATRAITQMFFDNGDYFRLLDRAQKAGITQPIVPGIQPIHSFKQISSFAAKNGAKVPRWL
AERFDGLDEDPETHALVASAVAAEQVLELVDEGITEFHFFTLNRSNFVLALARLLGVRPD
>A0A522FV53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MSVIDKIKNAAGPLFTFELLPPLKGHSIERIYTAIDRLIEFNPAYINFTSHRNETTYFER
PDGLLEKRIVRIRPGTIALAAAVKYKYNITVVPHILCGGFSKEETENVLIEMNFLGIDDV
LALRGDPQKGSRRFIGEKDGHTHTYELVRQIANMNNGKYLESTLEDTAPTNFCIGVAGYP
EKHFEAPNRQVDIENLKHKVESGASYIVTQMFFDNRKFCRFRDECRKVGITVPIIAGIKP
ISAVNDIKLLPQSFHIDLPNDLVTAVEKCKTDKEAREVGIEWATQQSKELIKEGIPGIHY
YTLGRSDNVARIVRGSF
>A0A2C8YSM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWT3|TrEMBL
MKIIDILKLDKMSLSFEVFPPKKETSFENVKAATESIAALGPAFMSVTYGAGGGVSHFTL
DIAKNLKEKFNIPMLAHLTCVSSSKETVHQRIDDMKAAGIKNVMALRGDLTPELIEKGRD
NCDYHYAVELIRELKAADADFCIGAACYPEKHPESANQAEDIKHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKSF
>C9QNK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio orientalis CIP 102891 = ATCC 33934|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELIQIADDYWANGIQSIVALRGD
IPPGGGAPEMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRSVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAQQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQG
>A0A4Y1XR73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes communis|TrEMBL
MNVLDIIRETSARETTRFSFELLPPLKGDGTRSVFTTIEALREFDPAFINVTFHRESIKE
TLTPDGHIEWHRMRRRPGTVGISAAIRDRFGIEVVPHLICGGLSRYDIEDALIDMDFLGL
HNVLALRGDCGPNERHFMPHPQGHSHAIDLVRQIAAMNRGEFVDGEVEECHHSKFSIGVA
GYPEKHVDALDAESDLRHLKAKVDAGADYVMTQICYDADRILAFISRCREAGIDVPVIPG
VKPLSTLRQLTLLPETFAIELPEALRSEVRTHADRPEAIRRIGVEWAVDQCRRLKAAGVP
VIHFYTMGRAENVRQIIKEVF
>A0A1V9ZG41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achlya hypogyna|TrEMBL
MGKIIDRLVELEKTGTPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSGFK
DEKLWLKIGAHIQNEFKIDVLMHLTCHLPQEQLRVILQNARNAGIRNILALRGDPPIGAE
RWKAVPGGFRNAVELIRFIRQEHGDYFCIAAAGYSEVHTEAWNNPNLPPSDQVRHLDMVR
LKEKQDAGADFIITQFFFDVDKLTQWIRDCRTVGIRVPILPGYLPIQNYNSFLKFTNWCK
TSVPDHVVQALNSIKNDDAAVKKYGIELAIDTCRKLMGQQLSLHFYTMNLASSVRSVLEG
LNLIPRRHERDLPWGLPMLRRKDGSADKIEQVRPIFWSNRASSYVARTSEWDDFPNGRWG
DRSSPAYGELSEYYLAYKRPKVARERVWGTPASEQEVWSIFVKFIEGSIKTLPWCEQGLS
GESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKGGFVFQKAYVEFFVPPHL
MERLLVALKDYPNLSYHAFSANGTEYTNAPGPSVTAVTWGVFPGQEIIQPTVVDSASFAA
WKDEAFELWMSQWASAYSSDSVAHGVIKQIYDSYVLVNIVDNDYTNEDSDIFKIFARVIT
EGMTKDDLRGRVLELEEKNEKLHETVAKLKIIQSEASRELKETHQELSASREEVNRLKTQ
LRELRARVALSAI
>A0A2V2YVJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus cellulosilyticus|TrEMBL
MLKDLILNKQSGILTYGMTPPKEDNTEEKITEIAQKQIERLKGLDIDALILYDVQEESDR
IDQERPFPYTTMLDPELYSKQYLHTLEVPKIIYRCVGKYSESELSQWVQKDIEQQRYTVY
VGASSSQQAVKLELADAYRISKMNNDKLSFGGVIIPERHMVKNDEHLRVVNKVKQGCDFF
ISQATYNVEASKNFLSDYYHYCNENEIEMVPILFNLAPCGSTKTLDFMKWLGISIPRWLE
NELKYSSDVLDKSIQLTSKIFEELYEFGLEKGIPIGCSVESVSTRKVEIEASIQMVKDIK
VMLDKKRLVDVSR
>E9HJT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Daphnia pulex|TrEMBL
MCSSSASASGEDTPNRDGERCQSPTDFDYTSGNKSLAEKIRLRIESGDKFFSLEFFPPRT
KEGAVNLLARFERLRLACPLFCDVTWHPAGNPGGDTETSSMTIASAALNYCGLETMLHLT
CCNLSREDVTKHLNRAREMGVRSILALRGDPPIGQDWQPPENGLGYAVDLVRLIRDLFGD
DFSICVAGYPTGHPDATSYEDDLLHLKEKVDAGADFIITQLFFRAETFIKFVRDCRALGI
DVPIIPGVMPIQSYDSLRQIAKLSKLEVPQEITDILAPMKDNDEAIRNYGVQQAVTLIRE
LFNAGVAPGIHFYTLNREVATTAILKQLGLWVTDPRRPLPWRRAANAKRSTETVRPIFWS
SRPKAYIYRTRHWDEFPNGRWGKSDSPAFGELKDYYLFYLKSKSSKDDLLRMWGEELCSE
QDVWDVFHCYLSGQLNKSGCKITKIAWNDEELSSETSLLQEKLSEFNKKGVLTINSQPNV
NGAPSDDPVVGWGPRGGYVYQKAYLEFFTCQANVQALLKVLPSFSRVNFHIINSNGKADY
TNCHRHRPVAVTWGVFPGREVLQPTVVDPVSFKVWKDEAFALWREQWGKLYPEGSSSRDL
LTRISETYYLVNLVDNDFPRESCLWDLLNAMFAQRQLDNMSDFIQQDSDVHLGDDFDDAL
KMMRRQHSRGDTSYTHYTMEELVEAAHRQEVHSDEIVTGEGHQ
>A0A5B8VGY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panacibacter ginsenosidivorans|TrEMBL
MKVTDHIQQAKDTLLSFEILPPLKGKSIQSIYDHLDPLMEFKPSWINVTYHRSETAFKKK
ADGNFEKVEVRKRPGTVGICAAIMNHYQIDAVPHMICGGFTMRETEDALIDLNFLGIDNV
LVLRGDAAKNEASFEPEPGGNKYAIDLLKQVVHLNSGIYIDDDIRDGGKTKFCIGVAGYP
EKHFEAPNLEIDLRRLKEKVDAGAEYIMTQMFFDNNKFFEFVNACRANDIHVPIIPGLKP
ITTKKQLSVLPRIFHVDIPTDLSTEIMKCKTDADCEIVGTEWLIQQSKELKVFGVPVLHY
YTLGKPRLIRDVVKEVV
>A0A553EQL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fulvivirga sp. M361|TrEMBL
MKVTEHIAKAKKTLFSFEILPPLKGENVKDLFGHIDPLMEFKPPFIDVTYHREEYVYKKR
ENGLLEKKSTRKRPGTVGICAAIKNRYNVDAVPHIICGGFTKEETENALIDLDFLGIDNV
LVLQGDAIKTEPAFVPEPDGHRYASDLLEQVVEMNNGRYLDEEIQKPTPTDFCIGVAGYP
EKHFGAPNLKTDMKYVKMKVDMGAEYIVTQMFFDNQKYFEFVDLCRSMDIKVPIIPGLKP
ITTKRQTTVLPRVFHIDLPEDLADAVDGAKDNAAAKQIGVEWCVQQSKELMDKGVPVLHY
YSMGKSDPIYKIAKALY
>A0A7W6S0B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseospira goensis|TrEMBL
MPYDSLHAAPVAARAVAPAAVPDGVSLEVTPGVAAKIPSFAALLPPGTAVYVTNLPGTDV
AQAMTLCRRLRDEGLRPVPHLAARGLKSRADLADWLDRAVHQGGARQILLIAGSGDRPAG
PFRDTLAVLDSGLLEAAGLEGFGVAGHPEGHPNAGPAVLREALLRKQAFAESHGLSAWIV
TQFAFSAAPVLRWAEGLAAAGVTLPIRVGLPGPAKPATLITYARQCGVGASLRVLTRRPD
VMAGLLRAWTPDAIVADLVRAGRSEGPARIAGVHLFPFGGFAKAAGWAGAALGGPAGAAV
AAAH
>A0A4U8WLB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium taihuense|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYVYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHGSAMELVHQINDLGRGKYLHNQDEVCDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVQKAREMGIMVPIIPGI
KPIATKKHLKVLPQIFKIDLPEELISEVENAKNNEAVKQIGIEWAIAQCRELLKFEVPVL
HFYSMGKSDNIKKVAGALF
>A0A4Q6II32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. F001|TrEMBL
MTTFSFEFFPPKTEVGERTLWDAIRRVEALRPDFVSVTYGAGGSSRDRTVSVTRRIAAET
TLRPVAHLTAVGHSVAELRHIIGQYADAGIRDVLVLRGDPPGDPNGPWTPHPAGFTYARE
LVELVRSLGDFTIGVAAFPEGHPRSPDRESDLRHFVAKCRAGADYAITQMFFDVEDYLRL
RDRVAAAGCETPIIPEIMPATDVRQIRRFAELSGAAFPEDLAHRLEQARHDPDAAHRIGV
EYATAMAERLLAEGAPGLHYITLNRSTAALDIHRNIQTAAASVPAPRPTSGA
>A0A3D4IBP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter nauticus|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTREEIGELLDVYKENGINRIVALRGDMPSGMGASGELRYAN
ELVEFIRQHSGDHFNLEVAAYPEFHPQARNAEDDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEQMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCQKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A383Z4D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balaenoptera acutorostrata scammoni|TrEMBL
MDGPKPKVLPAGHCCPSLGMRAWEAGSARLSVPPSISRSSAMVNEPRGHGGPSPRWEGSS
SGSESSKDSSRCSTPVLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKRLGLKNILALRGGYPKGHPDSESFEADLKHLKEKVAAGADFIITQLFFEADTFF
RFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNY
GIEQALSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKR
REEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEEL
LKMWGEELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRR
GILTINSQPSINGKPSSDPVVGWGPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVN
YHIVDVKGDNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGK
LYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLNRPPQNKSETEAP
>A0A6G1J314|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentithecium fluviatile CBS 122367|TrEMBL
MHISQMLAQSKAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHNFGPKFIDVTWGAGGRLS
NLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDNALKEAHQAGCTNILALRGDPPREKEK
WEATQGGFRYAKDLVKYIRDRYGNHFDIGVAGYSEGCDDNDDVDELIDHLKEKVDAGATF
VVTQMFYDTDIFIDWVKKVRAKGIDIPIIPGIMPIHTHAAFLRRANWTRCNIPKHWTEAL
EPVKNDDAEVREVGKGLVAEMCRKLIDAGILHMHFYTMNLAQATRMVLEELELLPDVESP
LQKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDARSPAFGELDA
YGIGLKGTNEQNIKTWGTPKSIKDISDLFARYMGGKLGTLPWSEAPISKEAESIQQDLID
LNRRGFLTINSQPAVNGAKSSDPIFGWGPRNGYVYQKAYLEVLVSPEYIAELITRIERDE
ELTYYAVNKDGDLKTNSPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQDW
ANCHPSTSPSRYVIEDVMDTWYLVNIVHNDFHQQHAIFPLFEGLQVADMDKELHNTGITY
RSSAHGKLDTNGTKPLLEDLVQAAKSASSAVTNGVSGLTLSN
>A0A2K8UT88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLAPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKSTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHKIAGIVITPHMLRVLAQEKQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVET
KKELVPQLAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAEKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A512J2E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium oxalidis|TrEMBL
MPASTYRASREGCRPIRVSFEFFPPKTEEMERTLWSSIERLAPLHPSFVSVTYGAGGSTR
ERTHNTVARMVRETNLKPAAHLTCVNATRDEVDEVVRSYWDVGVRHIVALRGDPAEGVGS
AYAPHPGGYRQTCDLVAGIKRIGDFQVSVSAYPEKHPEAASLDADIDALKAKVDAGADRA
ITQFFFENDVYLRYVDRVRARGIDIPIVPGILPVQNFKQAANFARRTGASVPEWLAHRFE
GLDDDVDTRRLIAGAVAAEQVLDLVDRGIHDFHFYSMNRADLVYAICHLLGLRAERPAAA
ERAAA
>A0A5E7ZPB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. EC-HK427|TrEMBL
MSSAPPLAPFPGALTLDEAQEKRRSRETPLFSGLPGDIDISFEFFPPKTAAMEEKLWEAV
QELAPLAPEFVSVTYGAGGSTRERTHNTVARLIKEAGIPAAAHLTCVDASKAETQAIAEA
YWEAGVRHIVALRGDAGEPGAPFVPHPEGYRNAAELVAGLKEVADFEISVAAYPETHPDA
DCPQSDLDNLKRKIDAGATRGITQFFFSAEKFFDFEDSCKAAGIDAPMVPGILPVTNVAQ
ARKFAGQCGAVIPEWMDGLFEGLDERPAARQLVAATVAAELCRRLYAGGVRQFHFYTLNR
ADLAYAICHMLGRRPMEAAR
>A0A2N1S5T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetae bacterium HGW-Spirochaetae-4|TrEMBL
MKVTEIIAQAKGPLFTFELLPPLKGHTMDAINETIETLLPYNPAYINITNHQMEVVYVDR
PDGLVERRTTHKRPGTIGLAAAIQYRFGIPVVPHLICGGQTKEQLEDQLVELNFLGIENV
LALRGDPPHGERRFIAAKGGYDHTDGMVSQIAAINRGEYLDPTLRDPVATSFCIGVAGYP
EKHAEAPNFNHDITMMKRKIDAGAHYIVTQMFFMNERFFEFVDQCRAAGIEVPIIPGIKP
IQRRSDLDLLPQTFRVDLPVSLVDRIERCKTAADIRKVGVEFCTAQVAQLLEAKVPGVHF
YTQGRAEPIANVVEATYPKAILS
>A0A432IGH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriia bacterium|TrEMBL
MKITEHIKKAQGKTLFSFEIIPPRKGQHIQKLYDNIDPLMEFKPPFIDVTTSREEYIYIK
KNDGLLERRITRMRPGTVGICSSIMHKYDVDTVPHVLCGGFTREETEYVLVDCHYLGIEN
VMALRGDAMKHESYFTPVENGHHYASELVAQISELNKGRYLHDIIDTPHPTDFCIGVAGY
PEKHLESPSMEADLRRLKQKVDAGADYVVTQMFFDNKKYFEFVEAARAIGITVPIIPGIK
PVSVQRHLNVLPQIFRINLPDDLVKEIEKSSNNNQVREIGIEWAVQQSRELIAAGVPVVH
YYSMGRSDNIKAIASQVF
>A0A5F0DGB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. HLT2-28|TrEMBL
MQKTSDPACSGRIPFSFELYPARTDAAASALETTIERLAAAGPDFLSVTYGANGSSRRSS
LDVLSRILRTTNVEAMAHLTCVGSTHEEANRLIREFLDAGVRSFLALRGDPPAGTKEGEA
FLGDFGSAAELVQLIHRVQAEKSPYRESIIPGIPAARAVKPGREKVRIAVAAFPNGHPRS
RSSAQDIDTLLAKQAAGANLGITQLFFHADDYLCFAQRAREAGVLFPLLPGIMPVTSPAR
LRRIIELSGEQMPSDLSIQLEIEPTKEGQREIGIQHAIDLAGQVIAGGAPGLHLYAFNEH
ETVLEVLGGCGLLTAPVSAPTKLPATV
>A0A6L3EZ00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNREEFRQRLAERPLLFDGAMGTMLHTKGVSVDQCFDAINLHNPAVVAEIHRGYIDAGAD
VIETNSFGANRYKLAEYGFQRDVKMINETAVTIARRVIESSFKPVLLAGSVGPLGVRMVP
LGRVTVAEVRAAYAEQIEALVFAEPKGVDFLVIETLSDPKELETAVSAARQIAPNIPIVA
EMTFTRDDRTLLGHASDTVAERLAKLDVDVIGINCSGGPAQVLRLLMVMRQIAPDKLLAA
NPNAGWPEHTDGGRVMYPATPEYFGRYAHALTEAGAVLVGGCCGTTEAHIAAMRKALDNP
QPPVITLPRVNIVSREERQTVVVDPPTQLAENLANETFVITVEMSPPKGIAAQRMLTSAK
MLKEAGANLLNIADSPLARMRMSAWAAAHLVQQQVGLETVLHFPTRGRNLLRIQGDLLAS
YAMGIRNLFVTMGDPTKIGDYPEAMDSYDIVPSGLIQLIKKQFNEGLDKAGNSIDQATNF
NVGCALSLTPKDVGREMKLLRKKVRNGADFAITQPVFDAETAVSFINRYESTYNEPIIPI
VAGIKPLYNIRNAEFLHYEVPGINIPDAMRDRMRHAAKPQAEGVKISQEILGEIRPFVQG
TYLMPAFGRYDLVADVIDGVRE
>A0A3M1JAI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSSKFLESLKSGPLLSDGAMGTMIYSKGIPTERCFDELNLTDPVIIAEIHRSYIQAGSNV
IQTNTFGANRIRLAEYNLAGSVVDINRAGVQLAKRVVDASFREVFVAGTVGPLGQWLAPL
GRLQKAEVAGIFREQTAALIEAGVDLLIFDTFADIAALKEAVVAARAVSADIPIVAQVTF
SEDMRTALGHTPQKVAEELGSLPIQVIGINCSLGPSGVLRALRQLARHVPPHIYLSAQPN
AGWPERIGGRIMYPATPEYFGEYALALVESGARLVGGCCGTTAEHITHMRAALDDPAPQI
TALPKLPGEDAEGVGPVSAVEPTRMARRLQNGQFVVTVELSPPKGFSGEKVLAGARLLKE
AGANAINVADSPRARMRMSPWAMCHLIQSRLDLETVLHFPTRGRSILRVQGDLLAAHALN
VRNIFAVMGDPTSIGDYPDALNDYDVVPTGLIKLLKQQFNAGVDHSGEPLSQPTNFLVGC
ALNLTPADPQRELKVLRKKIESGADFALTQPIYNPQEARAFIARYESEFGPWSLPIVAGV
LPLYNGRHAEFLHNEVPGINIPDEMRQQMRSAGSQSAQTGVRIARQLIAHIREFAQGIYL
IPAFGRYDLAAEVIEEIA
>A0A7C5NR71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSEDRTNGYKSGSRLERVLKAGHFAVTAELGPPQSADGEVIRKKAAQLKGYCDAVNITDN
QTAIVRMSSIGAGTIVVQEGLEPIIQMTCRDRNRLAIQSDLMGAYALGMRNVLCLTGDHQ
SFGNHPTAKNVHDLDSLQLVQMVVKLRDEHQFQCGDEVKGIEPRFFVGAAANPFGDPFEW
RPYRLAKKVQAGANFIQTQLIYNVPRFEEYMAKVRELGLHEKVYILAGIGPLKSPGMARY
MRDQVPGLDVPTEFVDRMTAAAAGIDKE
>A0A8G0V104|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus pinatubonensis|TrEMBL
MQDRYYSFEFFPPKTAEGAEKLRNTRAQLAPLNPKYISVTFGAGGTTQQGTLDTVLEIQR
EGIEAAPHLSCVGSSRESIREILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFQIEVAAYPEYHPQAKSPRHDLENFVRKVKAGANSAITQYFFNADAYFRFVD
DARAMGVDVPIVPGIMPITNYSQLMRFSDMCGSEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAGGVPGLHFYTLNAAGATKAIWQRLKL
>A0A7C4KBJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAVEYLAGSRLERILRAGGFAVTAELNPPDSANPQEVYEAAVVLSEVCDAINATDASGAN
CHMSSVAICALLTRAGYEPVFQVSCRDRNRIAIQGDLLGAAAMGVKNVLCLTGDDVTAGD
HPEAKRVFDLDSIQLLRMVSIMRDRGVFLSGRKITTPPRFYLGAAINPFVPPFDWQAHRL
AKKIAAGANFIQTQYCFDVPRFRKFMSQVRDLGIDQKVCILVGVGPLRSDKAAEFMRTRI
PGVVIPDELVERMRKTPKEKQRQEGKRICVEIIQQVREIPGVAGVHVMAYRQEELVAEII
EEAGLLPRPRQVYTEEEDRLRRPRKFRRQRPWAASPG
>A0A3L7XNJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MENTFLEALTRGLLLGDGAAGTLLRSRGWTGRLFEAVLDRPDLVRAAHEEYIAAGAELLL
TASFDANRSHLERRGYAGRVRDANFQAARIARDAREIAGVPLFIGGSVGPIGRDLQLGAW
TMDDAYEAFREQIGALVEGGVDLLVLETFPSLQEAETALRAARSITDLPVVAMLNFNADL
ATPAGETAAEVVRGLAASGADVVGVNCGVGPQAALDMLQQMAAACVEAGIEMPLAVKPNA
GLPRIVRGQEVYPSEPAYFADFALRAKDMGAALIGGCCGTTPPHVRAMREALGSVGGAAV
SSLSPHGAPQLDPPPLEEPAGAAAPSRLRDKLSAGKFVISVEIDPPRGINPRKAIEGAAL
LRDAGADAINIGDSPMARVRMSALALAVLIEREVGLETLIHQTTRDRNLMALQSDLLGAH
ALGIRNVIALTGDPAPAASQSSTVWDVDSIGFIRVLRRLNEGVDFAGNSLGRPTEFLIAC
AANPTADDLELELRRVREKLDAGAHMLMTQPAYDVDVVRTFFDRLGPIEVPVLLGVLPLM
SSRHTEFIHNELAGVVVPDDVRERMRLAGESGAAAGIEIALEHVEATRSLPFVSGVYLMP
SFGRYEVAAELARRIVASS
>A0A520QGM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sandaracinaceae bacterium|TrEMBL
MPAEKLIDVLRARPVVFDGAMGTALYERGVLYTNNMDQQTVTKPELVASVHRMHLEAGAE
VLQTNTFGANRYRLSSHNLEGDVDRINRAAVKLVQDVAAGNAWVAGSVGPSGTIFKTVPE
SEMDALRSAFREQAEVLVDAGVDLLVLETYRQPDELQLAIEGARAASQGKVPILASVSFD
AFGTMSDGTGPEEMAKRLADLGVDAVGVNCADGPAGVYEMAVRLLDAGLPVVAQPNAGLP
RRVEGRFAYMATPEYFLVYARRLYKAGVRGVGGCCGTTADHIRQIDQAARMLRGDDPPRD
SSPPDVAGQATRDFERMPEEEIAPGVEVTPLSDKGLIGERLAAKKFVVSVEVNPPPGLSL
EKALAGAAQLKAGGVDVINVADGARATARMGNLALCFRIQEQLEMPALMHVTTRDRNVLG
LVAHLLASHELGVKNLVVITGDPPKMGDFPDAKAVYDLDSIGLLRLINGMNRGFDPGGKP
LKGATSFLCATGAEPAAKDYDRELRRLEQKRDAGAEVVMTQPVYDPVVLERFLDDVRPMG
IPVLVGLLPLASYRNAEFLHNEVPGMSIPEDIRERMRRAGSGPDGRAEGVRIAREMLEAV
KGRVDGAYIMPPFGRYELALEVIDGIVR
>A0A0W1B315|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus etheri|TrEMBL
MKQDLRSAWGNKVLVGDGAMGTYLYQKGFPVGISYEELNLTSPGVIEDVHRSYIDAGAVL
LESNTFSANFDRLSKYGLESKVEEINRAGVRIARKAAGDTGYVLGAVGSIRAGKRANLSS
TELKKYFTQQITALLEEEVDGIMLETFYDVEELHLALRIVRKHSALPVICQFAVDESART
LDGLTLPEAFRILEGDGADIIGFNCNTGPNGIKRALKAVQGNLVLPTSVYPNAGVADYVD
GEYRYGASPEYFGQMAVTFAEMGCRIIGGCCGTTPQHIAEISSALKGYVPQPLPEPSLVT
VERVSLQEDFGEAEEKDGREPNLVDLVKERHTVIVELDPPRDLDIAKFMQGAEALRRAGA
DALTLADNSLAVTRMSNMALGHLVHAKTGLRPLVHIACRDRNLIGTQSHLMGFDALGIDH
VLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGISFSGKPLKQKADFVIGAAFNP
NVRHLDKAVQRLEKKIASGADYIMTQPVYDQELIVRIAEATAHLDIPVFIGVMPLASGRN
AEFLHNEVPGIQLTDEVRNRMKGLEGEAGRAEGVAIAKELLDVAIAHFNGIYLMTPFMFY
DMSAQLMEYVWEKSGRKLSPLFR
>A0A1C3F516|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp. BG|TrEMBL
MENKFKESILDKNVLSVTWELVPGRGANEKAQQSAIASSEQAAKGGRVHALTITDNPGGN
PAMLADYLGVEILGMGIEPLVHFTCKDKNRNQMESQLYALDRAKVRNLLVMTGDYTYTGF
EGRPKPVFDLDPCNALKLISEMNKGLEIPGMKGPTYHAPSDFFAGAAFSPFKATEAELMV
QYYKLKKKIEGGAKFIVCQLGYDARKFHEVIQFLKVNKLDIPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNTEKTAADKGVGTRMLRAAKLYAILKGIGCAGVHIGGHNLKYEQ
VEYIIDEGEKLYPKWQELVKEFDYPQPNGFYYFEKDEKTGLNTDRPTNRAKLPLDAPAGA
GYSFMRKMHALMFTPNKKLFGMMRGIYISAEGKKRMKKLHFFEHMAKVAMLDCKDCGDCA
MLDLAYLCPMSQCPKNQRNGACGGSFNGWCEIYPNEKKCFWVRVYARLKKYGEERSLDVP
MVPPPNWDFYQTSSWANFYLGKDHSAPILGIKRPPSKVPVSK
>A0A4V3B846|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus qingshengii|TrEMBL
MSLLEKLEKQILIADGAMGTLLYSFGKDSCLEELNLSHPEKIQEIHKAYIDAGADVIQTN
TYAANYLKLQRYGLEDSVKAINSAAVQNAKLAAQQNAYVLGTVGGNRGIKPSALSIEELK
RSFREQLYCLLLEEVDGILLETFYDLEELETVLTIARKETKLPIIAQVSLQELGILQDQT
PINEAFTRLESLGADVIGLNCRLGPHHMLKTLEQIELPKHAYLSAYPNASLPAYTDGIFH
YEGDADYFKKSAQSFRQEGVRLLGGCCGTTPAHIQAFASELKNSVPITEKVVKLKTKKII
IEQSAAKRDHQPLEEIVKERPSVIVELDTPRKLDTSKFFEGAKALKEAGIDAITMADNSL
AQVRISNESLGYLVKQELGMRPLIHIACRDRNIIGLQSHLMGLHTLGMHDVLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTAFSIAGAFNPNVRSVEKAVK
RLEKKIEYGADYFISQPVFSEEKLIEVYEHTKHLNAPIYIGLMPLTGSRNAEFLHNEVPG
IKISQPIRERMAALNDQPHQAAREGIEITKSLIDTALDLFNGIYLITPFLRYELTTELAI
YAKQRASQVRGNNYVESSIQ
>A0A7C7DRD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
GGCCGTTPMHIRAMRAALDEHLAARSSAPAPTLTVVEETPSATKADYGVTGEVQPTEILR
KLRAGKFVISVEVDPPRSFTAEKQIEGARHALKMGADAVNVADSPMARVRMGALALCVQI
QQQVGIETIVHFTTRDRSLMGLQADLIGAHALGVRNILALTGDPPSLGDTKQSTAVYDVD
SIGLVRIINRFNDGVDVAGQDMGQKGGFTIAVACDPTRSDLVQEVDRFHQKVSGGAHFTM
TQPIFDPQLWVNFVTLYEERHGTFPVPVLIGVLPLQGHKHASFLHNEVPGITLSEDALER
MRKAGANGRQEGVKMAQELLLELKELPYVQGVYLMPSFGRYETACQVLEVIPARERFGS
>A0A7C3HVR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTDETVFKSGSRLERVLRSGRFAVTSELNPPDSADPEDVYRAALVLAGVCDGINAVDASG
AHCHMSSVAICALLTRAGYDPVYQVSCRDRNRIAIQGDLLGAAAMGVGNVLFITGDDVTV
GDQPEAKRVFDFDSIQAIQTAKIMRDEAMFLSGRKLTTPPRLFLGAAANPFGPPYDWRPL
RLAKKIAAGADFIQTQYCFDVPRFAAYMKRVRELGLHEKAFILAGVGPLRSERAAEFMRR
KVPGVVIPDVVVERLRKTPKKQKRVEGKHICVEIIQQIREIEGVAGVHVMAYRQEELVAE
IIEEAGLLPRPKR
>A0A2E5E4Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MEPLSLVSNSFREILETEGRFLTAVEIETSRGLLMAEASRKTAELAKSLSEFNQIDLVCL
TDNPGGNPHIRPEVLGQDLLFRGRDVVINLSCKDYNRNGIESRLWALGSQGFTNVLALSG
DYPIGGFKGQAQPVFDIDSVGLLQLMSEMNEGLPNRMWGSVGREDRLERTNFFAGCAISP
FKKFEGELMTQYFKLAMKVRSGARFAVTQIGYDSRKLSELHTYVNSNNINVPLLGSVFIL
SAPAARFFNQWGVPGVWVSDELKAIANKQAKSKDRGRLFFSELAAKQIAILKGIGYSGVY
ISGRPQLARIQRIMEIVDSFGENDWKSFTSEINFSQQDEFYYYERGENAGLSSDVLNTSY
VSSKTKAARAKSRLSVPIKYRFGKFVHDRVFDKHSLGFKIGRAVYGKIDKNKKLATAAHV
FEQAAKVPVYQCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTKAGKCEILDEQCIWLR
AYERLKPFGDEEKMLERPVVFRDGALKNTSAWSNTFLSRDHHGRQSSDDADAGE
>A0A447UDN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus lutetiensis|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYETYNLTHPEKVLAIHKTYIEAGADVIQT
NTYTAKRHRLDGYGYGEKIKEINQAGVKIARQAAGEDTFVLGTVGALRGLKQCELTLNEI
IKETLEQVRYLLETEEIDGLLFETYYDEEEIIEVLKVVRPLTDLPIITNISIHEAGITEN
GRPLVEIFGKLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVSRKFVTP
MVEEAELIKAVKQSETIVDKVERKVTIIAELDPPKTLDIRKFTKGVKALDEAGVAAITLA
DNSLAKTRICNVSIASLLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIKQLNKGIGYSGASIKKETTFTAAAAFNPNVKNLS
RCGRLIERKIAAGADCFITQPIFNSEIIENLAELTRDYDTPFFVGIMPITSYNNAIFLHN
EVPGIQLSDDFLAKLEAVKDDKEKCQQLALEESKQLIDHALKFFNGIYLITPFMRYDLTV
DLVEYIHQKVEQSHQIIP
>A0A7C2WFZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MIWTGRAVGGTLKHVAFAAELRAGSFPVSLEITPPQRLLRGVLLRRARLLGDCVRTVNVI
QRPDRLPSLDASIELLRHGFEPVWHLVTRGREEPDVRADIVRAAEAGIRHVLCLLGDHTV
EREPERPLRIRDAITLVRALAPAMSVGATLNQYASSSDAVLRNLLPKVEAGATYVQTQPV
VELEPFARLAERVRREVPELRIVAMVMPLLSLESVQRVTARLDVAVGEAVLSRVAADEGW
QVFRETVGSLRRSGLADGLAVMTFEMDPPPEVGVRIREALVEAGVISC
>A0A497AA33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAEERTNGYKSGSNLERILRAGHFAVTAELGPPQGADPEDILRKARILKGVADAVNITDN
QTAIVRMSSIASGVLAMSEGLEPVVQMTCRDRNRLAIQADLLGAYALGMRNLLCLTGDHQ
SFGNHPTAKNVHDLDSVQLICMVKDMRDEGCFQCGDAIKGVEPRFFIGAAANPFGDPFEF
RPYRLAKKVAAGADFIQTQLIYDIPRFREFMKRVVDMGLHEKVYILAGVGPLKSSGAARY
MRDKVPGMIVRDEYVERMVAAIKGIPKEDKKARREAWRKTGIQICIEQIQEIREIEGVAG
IHIMAIEWEEAVRPIVEGAGLLPRPTVE
>A0A535K231|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
GEFPDALALLSALPEDHGLTEIGVTGYPESHPFIHDDMTIQAMWDKRRFATYIVSNMSFD
ADTVKRWVERVRRRGVELPIYIGMAGVADPARLLRLSTKIGVAESARFLRGHPSWLARMF
RPGGYEPGRFVGALLPDIAQHARRIAGLHVFTFNEIEPTERWRREMLSRLSQGEGA
>F2CFW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis SK408|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTFAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A3D0UPH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
METEFKSDGRLERVLRSGRFAVTAELNPPDSANPQEVYDAALVLSSVCDAINATDASGAN
CHMSSVAICALLTRAGYAPILQVSCRDRNRIAIQGDVLGAAAMGVCNVLCLTGDDISVGD
QPQAKRVFDFDSIQLLRTIKIMRDEGMFLSGRKLTAPPRLLLGAASNPFVPPYDWRPLRL
AKKVEAGADFVQTQYCYDVPRLRQFLKQVCDMGLDERVYILIGVGPLRSEKAAEYLRTRV
PGVVIPDKIVDRLRKTPKHKKREEGKRICVEIIQQVQEIKCVSGVHLMAYRQEELVAEII
EEAGLLPRPMQPLARDSDPRARPSKRRRANRDGDQ
>A0A2G3MHK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. BJB304|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVKRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGANAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A3S7K001|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. ZAC14D1_NAIMI4_6|TrEMBL
MTAISFEFYPPKTDEQRGQLDRTAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
RFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIAFI
RAEHGDAFRIEVGAYPETHPQAPDALTDLKHFKAKIDAGADAAITQYFYNADAYFHFVDE
VQRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRRMLAYGDDSESVRAFGAEVV
ARLCQRLVEGGAPGLHFYTLNLAKPTVSVLKLLNG
>A0A1X7RUU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymoseptoria tritici ST99CH_3D7|TrEMBL
MHITKKLAAAHEKGDATYSFEYFPPKTAQGVQNLYDRMDMMHGFGPAFIDITWGAGGRHS
SLTCEMVKVAQSAYGLETCMHLTCTDMELSKVDDALKEAYNAGCTNILALRGDPPREQEK
WVETQGGFRYARDLIKYIKKKYGDHFDIGIAGYPEGPDESTTADEHIVYLKQKVDAGGTF
VVAQMCYDAELFIEWVQKCRDAGIPESVPIIPGIMPISTHAAFIRRANWTQARIPPAWHE
ALEPIKNDDSAVREVGRDLIVEFCQKLMAAGIMHLHFYTMNLAAAVRMVLEKLDLTPSAE
SPHPDIKPLPWRQSLGLNRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
SLDEYGIGLKGTNEHNRKLWGEPQTIDDISKLFVKYMSGKVETLPWSEAPINDEANVLVK
DLIELNNRGLLTINSQPAVDGVKSSHPTYGWGPRNGYVYQKQYLEVLVAPELIDTVIQRM
ENDEDITYYAVNHSGELKTNVTADGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYY
LGLEWSKCYEEGSKSRALITELTKSWYLVNIVHNDFRNQGGIFPIFDGLQVPGVNVEKLA
NGITNGHAENGKTTEENGKPETNGVPDGNNVVNGADKKA
>A0A423UKX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonibacter urolithinfaciens|TrEMBL
MRSVSDIYAAARAAGRQPVSFEIFPPKGDLTLETAHEVAAELADLLPDFVSVTYSAGGSG
NRQATADVAAMIHDDFDIPTVAHLTCLGATEESISRAIDDLKRKGIASVLALRGDRTADA
SAAEGPFRFAKDLVMRLADEGFCVGAAAYPEGHIECTDFRASVAHLKQKQDAGACFFVTQ
LFFDNAYFYRFREAADAAGISVPIACGVMPFLGKAQIQRMVFMCGASLPSPIIKLLAKYE
DDAVALRAAGIEYACAQLVDLQEHGADGLHVYTMNQPDIARACAGALRATWRPAGEVAVR
GAGEPVGGRA
>A0A2D8LDR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKEKFVVTIPVYKSGNTKLLNYVSEINCNTLIVPQISSVRTDPSSLAYHINQKYNKSVII
TINTIDTNLRFIQSRILGAELFKLNNFLITKGDAKSLQKSPIKQTKDSKAVFEHTATYVM
NSIKQMNKGYDFIXNKLDSNTECIFGSTIEINQTDKEYLKLINKKIKLGASYLVSNPIYD
VKMYKNFVTKFNKSXSKKIXIPIYVXIRMXLPXDSFFDQNXHTYKNNFQSNKLNEYIKLL
TSLNNAGVRNYNLILFDNNNADKKTLKEQVLMANKLISFSK
>A0A2M7PB76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_10_14_3_um_filter_51_14|TrEMBL
MPLKEKIEAGGFAVLAELEPPKGADFHSLLANADLVKGRVDAFMVPEMANSVVKASSLGG
CAFLQNRGFETVLQVCCRDRNRLALQADILAAGAIGIKTVMVVQGDDITFGDHHQARAVN
DVTLMQLLEAIAGLKNGKDMAGIELKGAPDFFVGSTFNAGAAGGALDLEIEELKKKKGLG
AAFVVTTPVFDTDIFEKLLVKLKPVGVSVIPTVLLLKSAGMARYIDRNVKNIFIPSQLIE
SIQKAPDKPVECVSIAGKLISRFKEMGAPGVLVSTIGWEEKLPQVLDEARL
>A0A536HXP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARITDLLAAGRTFSFEFFPPKDEDEQRLLTRTISDLQPLQPSFVSVTYRGGRISRERTT
RVVIDLLRTTDLTPMPHLTCVAHPRFELGEIIGGFRAAGLENLLALGGDPLPAEESYKEL
AYASQLVELGRHLGFESIGVAAHPAGHPKSPDLVSDREHLAFKLRLADFAITQFFFRVEE
YERLREELAALGVTKPILAGIMPITSLVSVQRMAQLSGYAVPDDIVRRIEAGGDDREEIR
RRGIEVATELCRDLLEAGVPGLHFYTLNFSKATREIYTKLGLVTHH
>A0A517W4X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia aquarii|TrEMBL
MTRISELYQSGTFDLSVEIFPPKSEKGDANLFKTLEELIGYQPAFVSCTYGAGGSTSKRT
IELCKIIQERFQTSATAHFTCVVSTREELIEWLKNASEAGINNIMALRGDPPEGQETFIP
ADGGLRYANELVALIREHFPKMGIGVAGYPEVHPDAVDAKTDLANLKRKVDAGADAVYTQ
LFFNNSCFHDFRERCVQAGIHCPIIPGIMPITEFKRIQRITAMCNSTLPVELKSKLESVQ
DDSTAQFEIGVEYAIKQCQELIDDGVPGIHFYALNRSPACKRIFEALGFHKR
>A0A535JWF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARITDLLAAGRSFSFEFFPPKDNEEQALLTRTIADLQPLKPSFVSVTYRGGRISRERTT
RVVIDLLHTTDLTPMPHLTCVAHPRFELGEIIGGFRAAGLENLLALGGDPLPEEESYKEL
AYASQLVELGRRLGFESIGVAAHPAGHPRSPDLASDRKHLAFKMNLADFAITQFFFKLAE
YERLRDQMAALGITKPIIAGIMPITSLVSVQRMAQLSGYAVPDDVVRRIEAGGDDRAEIR
KRGIQVATELCRDLLDAGVPGLHFYTLNFSKATREIYTNLGLVKT
>A0A197SRC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ERV7|TrEMBL
MREMLATGETTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRSGTVKA
TEQIAADSTLTPVAHLTAVGHSVAELRNMIGQYADAGIRNILAVRGDPPGDPMGEWVKHP
EGVTYAADLVRLIKESGDFCVGVAAFPEMHPRSSEWDTDVRHFVDKCRAGADYAITQMFF
RPESYLRLRDKVAEAGCTTPVIPEVMPVTSVKMLERLPQLSNAEFPPELKERILAVKDDP
AAVRSIGIEFATEFCARLLADGVPGLHFITLNNSTATLEIYENLGLHQQP
>A0A2S8H2T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia phosphatilytica|TrEMBL
METPNISIEFFPPKTPEGADKLRVARQKLAELNPKYFSVTFGAGGSTQHGTLSTVLEILA
AGHDAAPHLSCVGGTRESIRAILQEFKEKGIRRLVALRGDLPSGYGGAGELRYASDLVEF
IRQETGDWFHIEVAAYPEMHPQARSPQDDLQAFARKVQAGANAAITQYFYNPDAYFQFVD
NAHKLGVDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWIRLKLASFGDDSASIKAFGLDV
VSGLCERLLAGGAPGLHFYSMNQAAATTAIWQRITAA
>A0A2U2XAY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brumimicrobium sp. C305|TrEMBL
MKVIDHIKEAKDTLFSFEILPPLKGKSIQSIYNGIDPLMEFKPKFINVTYHREEYVYKER
DKGLLEKVSIRKRPGTVGICAAIMNKYHVDAVPHLICGGFSKEDTENALIDLQFLGIDNV
LALRGDPIKTEATFKPEVNGHNYAVELIEQIQNMNKGQYTLDDIHLEPTDFCVGAAGYPE
KHFEAMNMATDLQYLKQKVDRGADYIVTQLFYDNAKYFDFVKKCRDIGITVPIIPGLKPI
SNLRHISFLPKFFHIDLPMELSTELLKCKTNDEVKQVGIEWGIQQSKELKAAGVPCIHYY
TMTNSSEVRKIASELF
>A0A2S6WSF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 46|TrEMBL
MALGTASIRSDHARTVRDMLAAGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWDADVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLERIGSLTNAAF
PPALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSPQA
>A0A1B2H7U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola subsp. Diuraphis noxia|TrEMBL
MYRISEYYKDIVQQKKENIRNFSKCSFEFYPPKNLILENTFWPTVEKLSKLKPNFFSVTY
GANSGEREKTYHFAKTIYEQTGITTAAHLTCVNSTPDELKEIAKKYWENGIKSIVALRGD
TLNKNNFEHKMYAVDLVLLLKKIANFNILVAGYPEMHPESKNSEFDIIHLRKKVDAGANK
IITQFFFTIENYLRFRDNCIKNNINVEIIPGILPIYNFNQLQRFSSITNVKIPDWLFQIF
NGLDNDLITQKNIGSSIVIDMVKILSREGVKNFHFYTLNQSDTVYTVCHVLGL
>A0A2E4HB05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MXKIPDLAXNGSSXLKIICDFSPPXGGXPSLIGDLXGLNPDIVSVAYNPGKSVRVNPVAA
AAWIKANTKQDVVFTLATRDMNKVAIQSLLLGAQLLGLQNIVIVEGDGLSNRDRERFKAV
YDFQPTSLIESVRDMNQGKDFRGLKLRVATDFSVGATIDMGRPSDSEIPLAVRKAQTGAK
FFLAQAEFDPSVIARFRADFESHFDKGHAPPVFYGVQILAEDGIIFGNVPQGTRSELESG
RSGEEIALELIQNLMXQGVRTVYLVPPIFRGGRRDYDSARRVIESARRLAS
>A0A1B6D4U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clastoptera arizonana|TrEMBL
MLNMSENSILEKLKSNKKGLFYSLECKPNLNDNFNLVRDSLNSFNLMFASTPWHLRKGIY
NVKYLEPLAIAKTFQKHGITALLHLSATGMKKTNVKEVLKLAKEAGIKNIFALQGDRTFD
SPPSDFPHAYDLVKYIRENFKNTFTIGVGGYPRGHCDSTSYKDDLNFLKAKVDAGADFII
TQMFFEAEDFIKYVKDCRKIGVNVPIIPGVFTIQNMESLEFVARFCRVGVPQKMLSEIEL
LKSEEQILNYGIKTSVNIIKEIIDAGINVRGIHFFTLNKYKPSYEVKKQIEEFISKKS
>A0A7V5DWQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
TVLHVTCRDKNIIGLQSDLLGCAAAGIKNLLIITGDPPKLGDYPQATAVFDLDSIGLTRI
ASRLNQGVDIGGKEVNPPTAFLIGVGADPTHLDQERELDRLAKKVEAGADFCITQPVYDV
EALLTFLERIRHLRLKVIAGVWPLASLQNARFLNNEVPGVRIPESLMKRMEKAGSKEEAR
ATGIAIAQEIIQAIRPHVAGVQVSAPFGNVDTALKVLSIGS
>A0A6L7GP02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia mangrovi|TrEMBL
MPGPYTVQVTSTANPAPSIVERLSAPHRGPVPFSVEFFPPRDAEAEARLWRAVRTFERLG
PAFVSMTYGAGGSTRDRTARIAGELATQTTLLPVAHLTAVNHSVDELRALVGSYADNGIT
NILALRGDPPGDPLGEWVRHPEGVEYAEDLVRLIADLGDFHVGVASFPEGHHRAPDLEHD
TRTLVNKLRAGAEYSITQMFFDVEDFLRLRDRVNRADPEQGAKPLIPGIMPITSLATVRR
MAELSGSVIPADVQERFAAAAGDGAEENREAVRAVGIDFATEMAARLVTEGVPCLHFCSL
NFAKATSEVLERLGVDTRSALPAASR
>A0A016VHW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylostoma ceylanicum|TrEMBL
MDTPGGSVPNLHERSSSDEEHLSFEVGHGNKYVPLHERINRRIKDKTPFFSLEFFPPKTA
NGVANFFTRLDRFNEGGPLFVDITWHLGSDPANMNKETSSSSIAAGCLDYCRVDTMLHMT
CAQYSKEQTIKHLEQSKSVGLRNILALRGDLPNIDADGIPIYKYRALDMIRWIREEFGDY
FTIACSGYPLGHPESPSYKADLLYLKSKCDAGAQFIVTQLFFEAEVFEQFVRDCREMGIT
VPIIPGIMPIMGYDSIRRIATLSQLTIPESILSDLEPIKHDDDAVRKYGTIKAIEMCRRI
LSNGSAPSIHLYTMNREGACREILQELGLWHKRPMRALPWEPHGSNHPLRCKEDVRPIFW
SARPKSYIYRTRDWDDFPNGRWGNSSSPAFGDLQDYYLFHLKAQTKKEDLLKMYGEELLS
FDDVKKVFTNFISQGVNENGVKVTTLPWNEQDVGVQAETKLINEQLLWCNENGILTVNSQ
PSVNGAPSTDPLVGWGKPGGYCYQKAYLECFISKENAISLLEIVDDYYPRINYHIINHDG
SFDHMNGEATTPIAVTWGVFPGAEIAQPTVVDPLAFRAWKDEAYDTWIKNWANLYPKDSI
SRNVIQKIHDDFCLLNVVDNDFQKPVIIYEILEKMLKRTEERKASA
>A0A519Z296|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax sp|TrEMBL
MSTLASSSLPLSLEFFPPKTPEGVDKLAAVRQQLYPLKPQYCSVTYGAGGSTQDGTIQTV
RAILSEGFDAAPHFSCIGASRAGVKEQLAQFAAQGIRRLVALRGDLPSGYGGFGEFRYAS
ELVDYIRAETGDHFHIEVAAYPEMHPQARSPQADLDAFVAKVKAGANVALTQYFFNADAY
FRFVDEASKRGVSIPIIPGIMPITNSTQLMRFSDACGAEIPRWIRSRLEGYGDDKASIQA
FGLDVVSELCEKLRLAGVPGLHFYTMNQSTSILALAQRLGR
>F9GFE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum (strain Fo5176)|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDDVKGDDERVKMVGVDIVSELIDKIKTIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A1G5GTT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoluna spongiiphila|TrEMBL
MTHDRFEVVVEVVPPSGADAEPLLAALEGINDLSFNGFSVATNPVAKPRMDALSLCRILQ
DELKRPATLHVTTRDHNRLSLQGILWGAKALGIKSVLVMTGDFVPLAEKGITSSVRDISL
TDLIKMARKAGLTTGVVMNPFTDELRLGIAMKRLKEKVAAGAQFVVTQPVYTARDAELLA
EALNPLGIPAHLGLLPLRTFRHAAFLHHKVSGIEVPEEVRSAMAKAENPTAEGIRLTRDL
LATARQHFHGACIMPPFDHFEILHGVLPREGNTGPTSK
>A0A1C5CJV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DconLS|TrEMBL
MAPSATRRRAPAALLRPGERSYSFEFFPPRTDTGERGLWQAVRRVEALSPAFVSVTYGAG
GSSRERTISVTERIRTETTLRPVAHLTAVGHSVAELRRIIGRYADAGIRDVLALRGDPPG
DPQGEWRPHPEGLRYAAELIELLKSVGAFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAG
ADYAVTQMFFRPEDYLRLRDRVAAAGCDVPVIPGIMPATSFAQIHRFAQLSNAAFPPDLA
QRLEAVRDRPDLGHRVGVEHATAMCELLLAEGAPGLHYITLNNSSAAVEIHRNLCPHRAA
APLPAA
>A0A1Y3W655|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricimonas sp. An62|TrEMBL
MKVIDILNNTDKAVFSFELVPPLKGGDINKIYEAIEPLIALAPPFINITFHRDEVVYREY
PDGTIKKVTVTKRPGSVALAAAIMRRYNVDMVPHIVCGGATRHKIENELIDLNFLDIENV
MALRGDPIPGERFFTPEEGGHQYSCELVEQITRMNHGQYLDDTLTDAVPTNFCIGVAGYP
EKHYEAPNQACDIENLKKKVDAGANYIVTQMFFDNSKFFQFIDKCRAQGITVPIVPGLKP
ISTFKHLEMLPRTFSIDIPHELVKEIRSCKNNKEINQVGIEWCVAQSKELIAHGVPAVHY
YTMGKSENIQEIVKQVF
>A0A520BJC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax sp|TrEMBL
MTASVSFEFFPPNTPVGVEKLKTVVQELGALKPQYFSVTYGAGGSTRDKTLNAVMDIAGA
GFNAAPHLSCVGSTRENIAEILATYRAQDIHRVVALRGDLPSGTATAGEFRYASELVSFI
RETQGKDWHIEVAAYPEVHPQQRYAARDLQHFADKMKAGADGAITQFFFNADAYFHFVDE
ARKLGVTQPIVPGIMPFHNYGRIAQFAQRDGIEIPRWVQMKMEGFMDDAASIRAFGLDVV
TKLCERLIAGGAPGVHFYTLNQSALTLALCERLGLGRQT
>A0A101V5U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces dysideae|TrEMBL
MALGTASIRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPQGLTYAAELVELIKTSGDFCVGVAAFPAMHPRSADWDADVNHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVAAAGCDTPIIPEIMPIASVRNLERIPSLTNATF
PDVLKERILTAQDDPAAVRSIGIEYATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHQPPQA
>A0A1G5IEB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoluna spongiiphila|TrEMBL
MASLFKQALDSGKFVVTCEVAPPKGTNLATMAHHVDLLKDKVDAMNLTDHQSSVMRFPSL
GAALLVKEMGGEPILQMTCRDRNRLALQADLLFAHSRGINNVLCLTGDSVMLGDHKEAKG
VFDLDSSQLVMAVRTLENGKDLGGSDLEGGISFCAGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVFDMAKFKSFMDYARQFPVKVLAGVILLTSAPMARFMNANIAGVYVPSDLID
EMTSAPKGGALKKGIEIAGRMIRQIREEEICDGVHIMAIGKEELVPEIMAAAEVP
>A0A0L6T7X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylibium sp. NZG|TrEMBL
MTATASKSLVPISFEFFPPNTPVGDEKLKTVVQELGSMTPEFFSVTYGAGGSTREKTLNT
VRAIAAAGFDAAPHLSCVGSTRESIGEILATYRAQNIHRLVALRGDLPSGTATAGEFRYA
AELVRFIRETQGADWHIEVAAYPEYHPQNRYAAHDLKHYADKVNAGASSAITQFFFNPDA
YFHFVDETRKLGASVPVVPGIMPFHNYGRIAQFAARDGIEIPRWVAMKMEGYLDDSASIR
AFGIEVVTKLCERLIAGGAPGIHFYTMNQSAVTLEICRRLGAG
>A0A652KP03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. gb1(2016)|TrEMBL
MALGTPSTRTDHARTVRELLATGETSFSFEFWAPKTEKGERNLWNALRRVEAVGPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVRYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDSDIGHFVD
KCRAGADYAITQMFFHPESYLQMRDRVVAAGCDTPVIPEVMPLTSVKQLERFAQLSNASL
PSSLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A5S4V2K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces mariniharenae|TrEMBL
MAETGQDAGGADCRPRTPVSFELYPPRSDAAALALGRTIDRLAEADPAFISVTFGAGGTS
RDRSLTVLRYMLENTDVEPMAHLTCVGSSHAEANRLVREFLDAGITSFLALRGDPPVGAD
SDEGIGDLDSAAELVQLIHRVQEEREPFAQVGIPGLPGVTQIGERPRPERVAVAAFPTGH
PRSRGAAQDVDTLLAKEIAGANLAITQLFWHADDYLGFVERARAGGVTIPILPGIMPVTT
PARLARLTELTGVEPPASLAIDLEIEPDAAAQVEIGIDFATRLAADVLDGGAPGLHLYTF
NRHEAVLDVVDRLGLGPHDRLVNERNTTER
>A0A1I4NUR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gracilibacillus orientalis|TrEMBL
MSNLITSLQNGLMVADGAMGTLLYSHGVDRCFESYNTTHPDEILHVHQTYLDAGAEIIQT
NTYGANYIKLSRFGLEDQVHQLNTKAVQLAKTAAKNRAFVLGTIGGIRGVQKIVTSKKEI
LRSFKEQLFSLLLEGVDGILLETYYDFEEIKQVLEIARQETDLPIIANVSMHEPGVMENG
IQLATALQTLEDIGADVVGVNCHLGPHYMIKALESVPLLEKAFLAAYPNASLPAYQNGKL
VYSQHSHYFERCAKDFRDQGVRLIGGCCGTTPEHIRALQDGISDLEPIKEKEIKQVTFTE
NTHDQQPPLRTTLADKAQKRHTVIVELDAPKHLDTDSFMDGVFALENAGVDAITLADNSL
ATPRISNLAMAVKMKQAGCHTTPLIHLTCRDRNLIGLQSHLMGLHTLGLHEILAITGDPT
RIGGFPGASSVFDVTSAELTKLIKQSNQGLSFSGSSLKTNTQFQVAAAFNPNVANLEKAV
KRMERKIKHGADYFLTQPIFNHEQIIELHRHTKHIDKPIFIGIMPLTSHRNAEFLHHEVP
GMKLSDEVRSRMQRHDNRQDSLQEGLQIAKELIETAMNYFNGIYIITPFMRYPLTVELTK
YVHQQAKSVTKIKN
>D6EJ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lividans TK24|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTNFVD
KCRAGADYAITQMFFQPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A8H4Q5T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps camponoti-floridani|TrEMBL
MHIKQMLAEAADGHKPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQSVCGLETCMHLTCTDMGLDKVNEALSKAYKAGCTNILALRGDPPRDQQT
WTATDDGFQYARDLVKHIRNKYGNHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDLGASF
IVTQMFYDADNFIRWLGRVRERGIHVPVIPGIMPIATYASFIRRANHMQCTVPPRWMEVL
EPVKNDDVAVRELGKTLVADMCRKLLANGVFHLHFYTMNLAQATRMVLDELDWAPCAERP
LHHALPWKQSKALGRRDEDVRPIFWRNRNTSYVRRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEVNRKKWGVPTTIRDLADTFVRYINQEMESLPWSESPLTGEADMIRADLVA
LNRRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPPDIVTEMVGRVESRP
SLSYYATTKDGDLMTNVPSEGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
AHCFDAASPSRALIDRIMNEWYLVNLVDNDFRNNRAIFEVFDGLQVKDLDVPHTP
>A0A0S8GKF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium SM23_30|TrEMBL
MTEITLKSESRLEKILASGQFALTGELGPPKSVDVDFIRQKAEYLKGKVDAVNITDNQTA
IVRMSSFAVALILKEMHLEPTMQITCRDRNRLAIQSDVLGAAAHGIHNILCLTGDHQCFG
NHTTAKNVFDIDAVQLIEMLRQMRDEKKFANGEEIKNSKKAPIKEPRIFIGAAVNPFADP
LKFRATRLAKKINAGVDFVQTQCIYDMERFNEWMKQVRNRGLHEKVKILAGVTPLKSVGM
AQYMRDCVAGLMVPDTYLERLSKAQDTAAEAINICVEQIHQLREIEGIAGIHLMAIEWEK
KVPEIAEKANLLPRPRV
>A0A1Y4I1V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeromassilibacillus sp. An200|TrEMBL
MNTATLFNAKKVVFSLEVFPPKKDTSVNVIYNTLLGLRGLPADFISVTYGAGGSPAQREK
TCEIASLIRSTYHIEPVSHLTCVNSDREEIRSILQKLKENGICNILALRGDKTPGVEPKT
DFLHASDLVRFIRETDPSFNLIGACYPEGHCESESLEEDIEHLKIKIENGVSHLITQLFF
DNGNFYHFLNLARQKGITVPVEAGIMPIVKKSQIERTVTMCGASVPSKLATIISRYADNP
AALMDAGIFYATEQIMDLLENGVQGIHLYTMNNVEVASRISRNIENIIAAKNAGENHHAD
TVQP
>L0GVX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioflavicoccus mobilis 8321|TrEMBL
MKDPLPIFSFELFPPKTAEGMRKLKDQVTRLRAVEPRYISVTYGAGGSTRAGTFETVDWL
CDQGLVTAPHLTCIGATRAEVRDLLQRYREQGIQRIVALRGDLPSGMGSGAHGDFRYANE
LVAFIRAEHGDHFHIEVAAYPEVHPQAVSAARDLDNFVRKVEAGADAAITQYFFNADAYF
SFVDNCRSRGLEIPIVPGIMPITNFTQLARFSDACGAEIPRWIRRRLEGYGDDIASLRAF
GHEIVAGLCQRLLAGGAPGLHFYTMNQANSTLKLWDRLGLSTRT
>A0A3R8LCN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bibersteinia trehalosi|TrEMBL
MSYARTTDLLNQNLAELNGKVNVSFEFFPPKTEKMESLFWDSIQRLATLKPKFISVTYGA
NSGERDRTASLVKKIQQDTGIISAPHLTGIDATPDELRQIAKDYWENGIRSIVALRGDLP
AGYNKAPFYASDLVKLLKEVADFDISVAAYPEVHPEAKSAQSDLIYLKQKVDAGANRAIT
QFFFDIESYLRFRDRCVTTGIDVEIVPGILPILNYKQLEKMAKITNVKIPAWLHHAYQGI
REEDKSTAQIVGANIAMEMVKVLAKEGVKDFHFYTLNRADLSYALCHSLGVRAA
>A1C6H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)|TrEMBL
MHVKDKLYQNEAGGQVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALSAAYKAGCTNILALRGDPPRDKEA
WEATEGGLRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSSF
IITQMFYDTDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPEWLEAL
EPVKNDDAAVKEIGKRLIAEMCRKLLAAGLNHLHFYTMNLAQATQSVLDELKLIPSEETP
LQRPLPWRPSLGLNRRGEDVRPIFWRNRNSSYIARTQIWDEFPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSIRDISQIFVRYVEGKLERLPWSDSPISAEANAIKENLIE
LNGRGLLTVNSQPAVNGVRSSHPVYGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKND
DLTYHAVAKEGELRTNTRDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRLGEDWA
KCHEAASPSRKLIQEVVDSWYLVNIVNNDFHNTYDLFELFNGLDVKDLDAEITFDTVEQK
PQLNGSANGVTPEDAAVKN
>S4MUJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces afghaniensis 772|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERMLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSTDWDTDVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDRVSAAGCDTPIIPEVMPIASVRSLERIGSLTNAAF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHRPQA
>A0A1C5RGC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKLAELFGKGRTVFSCEVFPPKKTSPVDSIYKTLDGLRDIHPDFISVTFGAGGSQVNQST
REIAGLIQNQYHIPAMAHLTCVAAGREDVDRLLEELKAEGVENILALRGDVNPDIPPKTD
FAHASDLVSYIRAHSDFGVSAACYPEGHLESPDLVSDIRHLKEKVDAGAQHLVSQLFFDN
EDFFRFLERARIAGIDVPIEAGIMPVLSRSSIQRMVSMCGASLPSKLTRILARYGDHPAA
LREAGIAYAIDQISDLIAGGVEGIHLYTMNDPAVAQQIAGSLTSIRSV
>A0A2B6FRH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6J6J1X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MPVCPLLRKTSAGPFETVTEALGTRSGRQEPSLSFEFFPPRNQEEAADQLWRSFDALMEV
SPDFISVTYGAGGSNRETSLAVVERMARDVMTIGHLTCVGGSRASTAETISRFEDAGVHS
ILALRGDAPQDNPDALKTGELKSALELVHLVRQTSNLEVGVAAFPEVHPESPHMEHDSMV
LEMKQSAGATYAMTQLFFTVDAYTDLVSSAKIAGATMPIIPGLMPVGNAAKVLRMAEMSG
AAIPVELLKELENAGSDAEARVIGMEYSIKLARDLVDAGAPGLHIFSMNLSKAALEVARG
AGLCR
>A0A1H0Q367|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacillus aidingensis|TrEMBL
MDLREALQNRTLIGDGAMGTLLYSYGIDRCFEELNLSHSEEVLNVHRAYVNAGADVIQTN
TYGANYIKLERYGLQDQVKEINTAAVKLAKQAAGENQYVVGTIGGVRGARKQAISTEEIK
RSFREQLYCLLFEKVDGLLLETFYDLEELTTVLKIARKETDLPIIAQVSMHEAGVLQDGT
PLPDALKQLEGLGADVVGVNCRLGPYHTIQSLEDVPLPEQAVLSAYPNASLPAYQDGRLV
YPTDPAYFQKSAQSLFDQGARLIGGCCGTTPEHIEAIAARVKGKQPIQDKVVPIKARTEV
RVSETKDDRPHLHEKAKKGRSIIVELDPPKKLKTERFLEGAKALHEAGVDSVTLADNSLA
SPRISNTAMASIIKQQYGVDPLVHIACRDRNLLGLQSHLMGLHALGIRQLLAVTGDPTKI
GDFPGATSVYDLNSFDLIHYIKQMNKGISFSGKNLGESTSFSVAAAFNPNVRNLNRAVGR
LEKKMKYGADYFISQPVFNEEQIIEVYEATKHIDAPIYIGIMPLTSARNAEFLHNEVPGI
TLAPEVLEKMELAGSDKEQAQAEGLSISKSLIDTALDLFNGIYLITPFLRYEMTVELTNY
IKQQTAERERKISNGIHIV
>A0A3A6CLZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. AF27-11BH|TrEMBL
MKDVREILKKRPLLFDGGMGTYYKAKPGQECEQANLLDPDGILTVHRAYLEAGADAIKTN
TFGLPRMAAAQNPMWEAMADEGWKLAAQAAAKTSAAVFADLGPAPDTEALPAAQIYTALA
ERFVALGAKNFLFETLSSDAGVAEAAKKIKETVPDAFVLVSFAVLPDGYTREGRHCAELV
RSMTACGAVDAVGLNCVSAPGAMRALVQQLGETELPLAVMPNAGYPVVTRTRVQYQGRPE
YFARELARLAAEGVRILGGCCGTTPAHIAALRAALDALPETLPAVPAAAVSTAAKPEVEK
DDAFLRKLNAGKKVIAIELDSPKDADMTGYLDGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGLNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPLTVFGALNLNARNFDVELRRAQEKLQNGMSGFL
TQPVLSAQAVVNLKKTRETLGEKAKILAGIMPVVSQRNAIFMENEVNGIHVDAEIIERFA
GLDRAQGEELGLEVSVKAAQAAAPYADGFYLMTPFNRIALMERLIARLKDEGIAD
>A0A7Y8J4T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriaceae bacterium|TrEMBL
MKVIEHLEKAKEPLISFELIPPKRGGDITDVLHVIDNIIKFRPPFIDITSHSAEVIYEET
PDGIKKKVKRKRPGTLGICALIQNKYNVDAVPHILAKGFTREETEDFMIELNYLGIDNVL
AIRGDESGYDKPIPVGKSANKNALELVEQIVKMNKGLYLEDSLLDARPTKFCIGVGGYPE
KHYESPNLKADIKFAKQKVDAGADYIVTQMFYDNKFYFDYVEKCREIGIDVPIIPGLKIL
TSKAQLHSIPKDFHVTIPSALSDEVE
>A0A5N7IS55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium estertheticum|TrEMBL
MNIKELPLIFDGAMGTYYANIKENPLSKCELANIYDRNTILNIHKEYIKAGCKAIKTNTF
GANKISLESDFNGVKDVIVKGYEIASEATKGTDVLVFADIGPIPFLETLDLWEAYKEIVD
LFLELGATHFIFETFSSDEYLPEISKYIKEKNPKAYILMELAVSPEGFTRIGISGEKFIE
KVSNISSIDACGFNCFSGPYHLLKYIKTLNIKNKTISVMPNSGYPTVINNRTFFNNTKEY
FARQMLEIAKQGVAIIGGCCGTTPEFIRETVANIEGLSPNEIVPSIKIEKIKFEKLIVEN
SLLEKIKLGKKIIAVELDPPMDTGIDFFMNSAKSLKEQGVDAITIADCPVARVRVDSSLL
ACKLKRELDITTVPHMTCRDRNINATKALLLGLSIEGVNNVLVVTGDPVPTAERDEVKAM
FSFNSAILANYITNLNETTFSSPFNICGALNVNAINFSSQLEHAKKKIENGVTMFLTQPI
LSKQAVDNLKQARRELPAKILGGIIPIVSHRNACFMNNEISGITVSDEITELYNGISKEE
ATILAIKISTDIAREIYDYVDGYYLITPFKRIDIISEIIKNIGNIGNS
>A0A1B9AG02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wudalianchiensis|TrEMBL
MSLLERLQNEVLLADGAMGTLLYSYGIDFCYEELNIEKPEIIEKIHREYIKAGADVIQTN
TYSANALKLTRYGMEDRVEELNKAAVRIARKAAAPSQRFVLGTIGGMRGIRKSSVSLADI
KASFQQQAEAILLEDPDGFLLETYYDFEELTTVLQLLRQMTDLPVISQVSMHEPGILQNG
LSLNHAFKQLEALGANVVGVNCRLGPYHTIQAFEEVTLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGQAAVHLRNEGVRLIGGCCGTTPKHIEAAKKALAGLAPVTEKKVVAKKPII
IKEPAPLVVPPLQEQVKKERTIIVELDTPKHLDTATYIKGAKALQQTGMAAITMADNSLA
SPRVSNLAMGSLLKMQHQIRPLVHITCRDRNLIGLQSHLMGLHALGLHDVLAITGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGISFSGKPLKQKANFSVAAAFNPNVRVLDRAVKR
LEKKIEYGADYFITQPIFTKEKIVEVYEATKHLPTPIFLGIMPLTSSRNAEFLHHEVPGI
KLSDETLARMKAHENDKEAAALEGLAIAKELIDTAAELFNGIYIITPFMRYEMSIELIHY
IEELDRKMNERGITHVQTIFN
>A0A7Y2FKP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospiraceae bacterium|TrEMBL
MKVLEHIKEGKGKTQFSFETLPPLKGQNIQSIFDTIDPLMEFNPPFINVTYHREEYIYKE
VGNGLLEKKVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAIKNETYFTAEKNGHKYAEELVKQIEALNRGEYLDDELQNHAQTDFCIGVAGY
PEKHSEAPNMESDIHFLKKKIKNGASFIVTQMFFNNKKYFEFVDLCRAQGIDVPIIPGLK
PLSTKRQLNVIPQRFGAELPDALIQEAIKCKSKESVRQLGIEWCIDQSKELMKAGVPFLH
YYSIGRSENIRKVALEVF
>A0A094Q1Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRLEKRMYSFEFFPPKDVAGEERLWQALSSLAALHPDFVAVTYGAGGGTRDRTIRITSEI
TARTSIPTVAHLTCVGSTRDELIDVLRRYTESGIKSILALRGDPVGGPRAPWAPVDGGLT
HADELITLAREHGDFTIGVAAFPDGHPNSGGDFGKDIDVLLRKESLGASFATTQFFFEVD
KWKRLVDALAKRGSTMPIIAGVLPVTNVKLLTKMAELGGTPIPDSIASRFAAVEDNPEDV
RKLGVEIALNLCNDLIDAGVPGIHFYTMNSSTATSEIFESLQDRR
>A0A7W9TV36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia bannensis|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLQHKPRFVSVTFGAGGSTQQGTLDTVAEIAK
EGVDAAPHLSCIGATRDGLRDILNQYRSHGIRHIVALRGDLPSGMGEMGELRYASDLVAF
IREETGDAFHIEVAAYPEYHPQARSPRHDLEAFAQKVKAGADSAITQYFFNADAYFRFID
DAKKLGVDIPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTDLCRRLVDAGAPGLHFYTLNAAGATKSICERLAL
>A0A7J4LFU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon|TrEMBL
MQKITELLRKKFTYSVELVPPRNGTDLKIVLDALETLRKIKVDFISVTKGAGGSLRGGTL
PICCLAHERFGITSVAHYTCREADSFRVENELVDQYYFGIKNVLALRGDPPDLTEHSVGK
TLKGDYKYAYELVRDIKKLNSGKYIARKKYDSTLENYREGIKTDFCIGVAAHPEEKDKDG
SYEKGLEYLKKKVEEGADFAITQMLFDAEKYRIFVAKARDVGIKIPIIPGIWPLDTRWKL
EQAEKKFKVSIPSKIKKEFSGIEDPEEFRKKGIELTVELCKKLKKYGAPGIHLFLFLDAN
IAEVIFDEMRKEKKS
>A0A4R0PQ60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. IC_126|TrEMBL
MTSLNRPSISFEFFPTKTEAGHEKLLATARRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKQELRELLNLYKEAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGASSAITQYFFNADCY
FYFVERVRKLGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMSSIQA
FGEQVISEMCEKLLVGGAPGLHFYTLNQAEPSLAIWDNLGLSR
>A0A0F9X7E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma harzianum|TrEMBL
MDKITEKIAALPPDGEYFSLEFFPPKTAMGFSNLRVRLQRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREIGLTTCLHLTCTNMSQALIDQALEDARALGIRNILALRGDPPRAEY
RDADEPDQASSEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPY
LVEKVQAGADFIMTQLFFDIGAYEKFETTLRNHPSGAFKTIPILPGLMPIQSYAMIKRTA
KLSHAKIPDETMVRLNAVKGDDEKVKMVGVDIVSELIEQIREIKSRTPGPKGFHFYTLNL
EKSISFILERTKLIPDVPDDEEAVVDETVVAAAQLVVPKISVNGNVPPRSSSHARTGRRQ
SSVGSDPHNRVIVGRAATHPEWEATSTEAGIPAESVNTRANTLAISEGEGALGREATWDD
FPNGRFGDARSPAYGEIDGYGVSIHMSVTQAVRLWGHPKVASDINDIFVRHIRGEISAIP
WSEEDLLPESSIIKSKLEAMNRKGWWTVASQPAVNGLPSTDSTFGWGPASGFVFQKSFVE
FFIPSADWKILYDKLTSAEVEEVVCFYASNAKGDFISSDASGGSGRAVMNASTNAVTWGV
FPGKEIVTPTIIEEVSFRAWSEEAFDIWAEWAKVYGRGSDSQKLLDEIKEDRWLVNIIHH
DYVDTEALWRLLIE
>A0A1T4Z6Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium choanae|TrEMBL
MPDSFDAALDDPILQALAADRPAVSFEFFPPKDDDGEAQLWRTIADLSPLEPTFVSVTYG
AGGTSQDRTVRITERIAREAPMPPVGHLTLVGQTRGEIETVLKQYVAAGVQHVLALRGDP
VGGPRAPWEPHPDGMDHAIDLVALVHEVGGLSVGVAAFPEGHPDCGGLDDDADVLVAKSR
AGASFAISQLFFRADDYFGLVRRVRDRGCDLPIIPGIMPILNFGQVARMAELSGAEMPRE
VLDQIEPIADDRAAVRAKGIELATQLCRDLLAGGAPGLHFMTLNRSPATREIFDELRADG
LV
>A0A0S2I4X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinivirga cyanobacteriivorans|TrEMBL
MKIINLFEKQKRIFSFEFFPPKDYLTAVKFGINAGQLMNLNPSFVSVTYGAGGSSHNHTF
DLVNFFQNELDFTCMAHYTVIGATKEKIRADMQALQDMGVRNVMLLRGDPPKGSKTFPEN
PHGFNHASELISFVKQNFDFCIGAAAYPEKHIEAASMDEDLDNLQKKVDAGADFLITQMF
FDNHFYWEFMDKVLKRGLKTRVIPGIIPITSFTQIKRFAEISGAKIPDRIAQVMEEIKSH
PEKVYKEGLNIAKQQSVLLLEKGAPGIHVFTLNKSRAAIDLYNHIPEIYK
>A0A3N5QBA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriales bacterium|TrEMBL
MKVIEHLEKAKNPLISFELIPPKRGGDIKGLLSVLDDITKYNPPFIDITSHAAEVIYEET
ATGIQKKIKRKRPGTLGICALIQNKYNIDAVPHVLTKGFTREETEDFLIELNYLQIQNVL
AIRGDDSGYEKPIPEGKSKNRFASELVSQIMNMNRGKYLEDSLLDARPTDFCVGVSGYPE
KHFEAPNLKTDVKYVKEKVDAGADYVVTQMFYDNAYYFKFVELCKEVGIKAPVIPGLKIL
TSRAHLTSVPKNFYINIPDVLADEVLAAKPEHVLDIGVEWAAKQVEELLNKNVPSVHFYI
MQNSKPIIKLMERLKL
>Q8DQT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae (strain ATCC BAA-255 / R6)|TrEMBL
MSRQTPSLSFEVFPPTPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIELIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDIAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A2H0P3T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG11_big_fil_rev_8_21_14_0_20_64_6|TrEMBL
MPELFGQGRPIFSFEFFLPKSPEDSDRFIADVKALKDLRPDYVSLTYGAGGSGRDRTVAA
AGRIQNETGLTTACHLTCIAHTRAEISVVLDRLSSLGIRHIVALRGDAPKDQPVAPPEQR
DFGYASDLVSFIKKRGGFRMAVAGYPETHPEAASAEDDLSRFATKAAAGADWAITQLFFD
SKDYFAFVARARAAGVTVPIVPGIMPVTSYAQLKRFMSLCGAKIPDELEARLAKIQDNQE
AVIREGVDWGARQCRALLEGGAPGIHFYTLNRSHSTTKILAQLRRG
>A0A2T3DAE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. NM-2|TrEMBL
MTAQTLYPAERGNLRLSFEYFPPKTDEMEAQLFQTAEDLSVFCPAFVTVTYGAGGSTKAR
SLTTVRRMIEEKGFANTAAHLTCVGAPKAEVDTVIDEFLAFGVRHFVALRGDPQGGIGST
YQPFPGGYESSSDLVRALRDRGDVEISVSSYPEKHPESPDVAADIDMLKRKVDAGATRAL
TQFFFDNDDFERYLERVRRTGIEIPIVPGILPINNLGQVQKFAGLCGASVPEVIVTRLSH
LEGQPAERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFERADEASRG
EDISLKAFAGAAA
>A6G2Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plesiocystis pacifica SIR-1|TrEMBL
MRISERLSHKRPVFSFEFFPPKHEKGERVLWRSLEQLRTLEPDFVSVTYGAGGSTRERTV
ELVARIKTELGIEPMAHLTCVGSTRDELARVVERLLAADVHNILALRGDPPKGETEFQHT
PGGFRYASELTAWLRESWPELCIGAACYPEVHPEASDAEADLAALKTKVDAGVDFLITQL
FFDNAAYFEFENRARGAGIEVPIIPGIMPVTNIKQIRRFTKMCGATIPPLLQHRLDDIAS
AEGGPHAHEVFWAGVSYAAHQCRGLLDPGRGAMPFGARTPGVHGIHFYTLNRSPATRALF
EILRLSRTAS
>A0A7W8HVY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas basaltis|TrEMBL
MTPSLSLAEARALLLSPLGPVARAGQDSSRPRVSFEFFPPKSDEAEANLWKAVTRLAPLE
PAFVSVTYGAGGSTRERTHRTVQRMLTETTLKPAAHLTCVEASRDEVDEVIRDYKAIGVN
HIVALRGDPPGGAGIGGAYTPRADGYANATELARAISRVGGFEITVGVYPEQHPESPSMV
HDIEVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGIMPVSNFAGLTRM
CGACGASIPEWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFADFHFYTLNRADLV
YAICRVLGVRENKAVA
>A0A7T2DAI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas campisalis|TrEMBL
MRDDNWGVDSSLPTNTPRYSSAGRLERVLKSGHFAVTAELAPPDSANPDEVYAKARIFDG
YVDSMNATDGSGANCHMSSVAMCALLSHAGHETVMQISCRDRNRIAIQGDVLGAAALGIN
NILCLTGDGVQVGDHPEAKPVFDLDSISLLEIIAKLRDKHVFSSGRTISDPPRVFLGAAE
NPFVPPFDFRPLRLAKKIAAGAQFFQTQYCFDIPRFKTFMARSRDLGLLEKCFVLPGMGP
LASAKTADWMRKKVPGIHIPDEIIKRLEGAKDQKVEGRNICIELIQQLREIEGVSGVHIM
AHRQEEAVSDIIKNSGVLGGRRPWSPYNDNSPRGSSHQKRCVLPLDK
>A0A8B3PID5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNDRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPYDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A1W9MCZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium A2|TrEMBL
MKQDFLTTLAERVLLGDGAMGTYLYSRGVERGQVIERLNLNEPDLVYSVHEEYIRAGSQL
IETNTFGANRFRLQLAAEQVREINRAGAALARRAAGSGAYVAGSVGPSGIEFPLEHGEIA
AADVEEAFAEQIGGLLEGGVDVLLLETFASLDEMLLALAVARRLCDLPIISQMVYPAGGR
TPDGVEALTCARAALAGGANVVGSNCGRGVQPMLAAIEQLGALRGVAPLSAFANAGFPEV
VGHRLVYPADPAYMARMLKEAVRLGVRLVGGCCGTTPVHIQELQHLLHVKKRTVAVLEPS
ARAETTPEAEAKPRGPGALLRGLREGTGLPLIVELDPPTHLDLAGVLEGARALATAGVDV
ISLAENPLAILRSDNLSLAHRIRMEQALPVILHLTCRDRNVLALQNQIMSAHHLGIDSIL
AITGDPAASSDQPGVSGVFDVQSFGLVRMISQFNQGRNFAGKDLRGHTDFSIGVAFSYRP
QRPETQLSRLEKKAALGAHYAMTQPFFDAAEVEQMMERAAHINLPIFPGIFPLISARNAE
FLHNELPGISIPAWIRERLGSFAQAEDQRKAAMEITRGLIEKLAPIVDGLYLISPLNKWQ
ITAQLAEEIRQAGWRGSGRLRA
>A0A480B540|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella tobetsuensis|TrEMBL
MTLREKHQNGQFTITVELDPPKSSSVQKVFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKDIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDHGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNGA
HFVQTQPIYDLEHAKRYIDTMSEFNVPIMLGLIPLKSFKMATYLHEKVPGISLTQDILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A1W1XI84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfacinum hydrothermale DSM 13146|TrEMBL
MKAGSNLEKVLTSGHFAVTGELGPPRGASVEAVEKKASYLKGVVDSINVTDNQTSVVRMS
SVAVCKLLVDMGLEPNLQMVCRDRNRIAMQSDLLGAYALGIRNVLCLSGDHNKFGDHPQS
KNVFDVDSVQLISIVKMLRDEGKMLSGQECEGVAKFFIGAAANPFGDPFEFRVTRLAKKI
DAGVDFVQTQCIYNMDKWRKYMHMAHEEGLTEKCYIMAGITPLKSVGMARYMAKFVPGLD
VPDYYIERLKGVEKKKQAAEGIKIAVEQIQEMREMPGVAGIHLMAIEWEHKVPEILEAAG
LLPRPKVD
>A0A1A2YBJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. E1386|TrEMBL
MSAGLECPKRMEFGPCGGVRPDGQCEMRPGACAFDDVVAWSGPQPAARPARAPLVLTDFS
CSPFDRRDDAATAAALAPGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDRN
RVLLEQELRGLRSINVETVLCVTGDGRGYDVRPDVTQTFDLDGPRLASLAASTGVVAAVP
ETPTAPPVHARPARLVEKQRAGASLAVLNHVPRPEIVADFMTMARAVGLAIPVIAAVAVF
TDNASAAVLEGLPGLKLDQAVTERVLGAPDPVAAGIAAAVAEARALLSIEGVDGVNVSGL
ASASGGRAGAEIKAEVGRRIRVGASS
>A0A1E5AHX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTTPKISFEFFPPQNLEASFRLWDTVQVLAPMDPRFVSVTYGAGGTTRSLTRDAVATLHK
SSGLNVAAHLTCVNASKAETLEIADQFAAAGVTEIVALRGDPPKGEGRFTPHPEGFANSV
ELIKGLKARGDFKIKVGAYPDRHPEAADQAADVEWLKRKLDAGADEALTQFFFEADTFFR
FRDACEKAGIDGSRLTPGILPIENWKGARNFAKRCGTIIPDWVENAFDKALRDDREELLA
TALCTELCSDLLEGGVDRLHFYTLNRPELTRDVCFALGVTPKVSLQNVA
>A0A2E7WNL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MTETDDEIHQPGRNVAPGYSSTGRLEQILRAGHFAVTAELSPPDSADPAEVYRRAALFAG
HVDAINATDGSGANCHMSSVGVCSLLTRSGYSTVMQISCRDRNRIAIQGDVLGAAAMGVS
NILCLTGDGVQAGDQPDAKGVFDFDCMSLLKTVCCMRDESRFLSNRKLSSPPKVFVGAAA
NPYAPPLDYRPYRLKKKIEAGAQFVQTQYCFDVQRFRQFMTRVRDLGLHEHCFILAGVGP
LVSARAAGWIRKNVPGVCIPDNVISRLQGARDQRQEGIAICIELMQQIREIEGVCGLHIM
AYRQERSVGEIVQGSGVLDGRRPFDPHSVHPS
>A0A2E8CLT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MNHNPRTDQPLRDGAVEAAQRLARRPRPSAVALHQNPQVSFELFPPATPDGWAGFVDTVD
RLDHLGGAFMSVTYGAGGTSQARTLQALQAMTACCVTPVAGHLTCAGATRDDVMAVVDTY
AEAKVKHIVALRGDPPKGHTAFEPHPDGFASAAELVSAIARRSHFDISVAAYPEVHPEAR
SSADDLDNLKRKIDAGARNAITQFFFEPDTFLRFRDRASAAGIHAPIIPGILPVVNLKRT
IAMAQSCATEVPTWLESLFDGLDNAPQVRSLISATVTAELCTRLHDQGVNRFHFYTLNRP
ELAWAICRILGLRGAGDPQSAQRDAAALA
>A0A529X468|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
ELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRAITQFFFDNDLYER
YVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFEGLENDPQTHALVA
SAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEATGSAAA
>A0A441HYG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MSIRHQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVF
LGAAVNPFAPPYDFRPIHLGKKIAAGAQFLQTQYCFDVPMFRTFMQKARDLGHTEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKREGKQLCIDIINEVKEIAGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>A0A0M2H5A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium ketosireducens|TrEMBL
MPIDLSAPPVPFSFEVYPPRTAERIPALHETIRHLAASGPRFISVTYGAGGSTGGRSLEL
LRHILDTTGTVPLAHLTCVGSTYAQANALIREFLDAGITSFLALRGDPPEGVSEDEVFLG
DLESAAQLAQLIDRVQAERSPYIERDIPGVPGAARVEGRRKADIAVAAFPNGHPRSRHPR
DHIDALLAKQAAGATLAITQLFFHADDYLSFVAKCRAAGVTIPILPGIMPITSPARLRRT
LELSGEKLPSDLAIALEVEPTAHGQREIGIAHAAALARAVVDGGAPGVHLYAFNNHDTVL
AVLREAGILSLEQERTG
>A0A162MY58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermovenabulum gondwanense|TrEMBL
MENRFKESLLNKEFFSITWELVPGRGAFEKNQEEVLMAAEQAAKGGKIHAITLTDNPGGN
PAILADYLASEIIKKGIEPLVHFTCKDRNRNQIESQLYALDRMGIRNLLVMTGDYPVTGY
KGRPMPVFDLDPVHVLELISKMNNGLEYPGIKGTVKHKPSDFFAGAVVSPFKATEAEQMV
QYYKLKKKIEAGAQFIVTQLGYDARKFHEVIQYIRQQGWDIPVIGNIYVLPIGTAKAMNK
NKIPGCVVTDKLVAELEKEAQAPDKGYKARLDRAAKMYAFMKGMNFDGVHIGGHNLKYED
VEYIIEKGEELSANWMDYIHEFDYPIPGGFYYYEKDPETGLNTSQPVDRKNRPLDTKVEF
VYKLSTLTHKLMLEPKAPLWKPMRAIAKRVDGTSLERPYHAFEHLMKVCLYDCHDCGDCA
LMDVAYVCPMSQCPKKQRNGACGGSFMGWCEVYPNKKKCAYVRAYARLKNDGKEEKLAGD
IIPPPNWDLYHTSSWLNYYLGWDHSASHLGIENNEKGKK
>F5L7C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldalkalibacillus thermarum (strain TA2.A1)|TrEMBL
MALLDDLQARVLIADGAMGTLLYSYGVGHCYEELNISQPEQIQAIHQAYLDAGAQVIQTN
TYAANYAKLSRYGLEDMVKEINVHAVRLAKAAANGRAYVLGTIGGIRGAGRKATPLEEIK
RSFREQLFWLLQEEPDGLILETYYDLEELSTVLQIARKETPLPIIAQVSLHEAGVLQGGI
PLSEALNQLEELGADVIGVNCRLGPHHMLRSLEQVPLPRRAYLSAYPNASLLNYVDGRLI
YQSEPDYFAQQARAIVEQGVRLIGGCCGTTPAHIQAMAGALKDVKPVTEKEVQPQLVQIE
EISLPPGPPGHKEQLQDVVAERKSVIVELDPPKHLDTGRFMEGASALKQAGIDALTMADN
SLATPRISNMAMAALIQQQLGVRPLVHVTCRDRNLIGLQSHLLGLYCLGIDHVLAVTGDP
TKIGDFPGATSVYDLSSIELIQLIKQMNEGLSFSGKPLKRKTSFSVAAAFNPNVRHLERA
VARLEKKIEAGADYFISQPVYDHAHLHEIYEATKHLPVPIYIGIMPLTSSRNAEFLHHEV
PGIKLTDEIRQRMAAVAHDPRLSQQEGLAIAKALIDTAYKLFNGIYLITPFMRYEISVEL
VNYIHAKQQTGKERELSHGRHIV
>W4GMG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces astaci|TrEMBL
MGKIIDRLTELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPREQLREILKNVRAAGIRNILALRGDPPIGSE
RWKAIPGGFQNAVELIRFIREEHGDWFCIAAAGYAEVHTEAWNNPNLPPSDQVRRVDMLR
LKEKQDAGADFIITQFFFDVDKLLQWIRDCRQVGITIPILPGYLPIQTYNSFLKFTNWCK
TSVPPQVEDALVTIKNDDSAVKKYGIQLAVDTCRKLLANNLSLHFYTMNLATTVRTVLEG
LHLIERERGLPWGAPITRSKDGTLEKSIEQVRPIFWSNRASSYIARTSEWDDFPNGRWGD
RTSPAYGELSEYYLAYKRPKVARDALWGRPQTEQDVWNVFVKFIEGSVKQLPWCEQGLSG
ESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPHLM
QRLVVALADYPNLSYHAFSANGMVVRVHLVIVCMATADKWRNRNGIHQLTRAECDCCDVG
GVPWQRDHPTNGGGHGQFRSVEGRSVRVVVESVGVGVRDGLAIAPVDQAHFRQLRPRERC
GQRLHQRGQRYL
>A0A2E4A0V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MVDSLNPGLNSPLGSIPKGLKVSFEFFPPKTEKMHENLWLAVERLAPLKPQFMSVTYGAG
GTTRERTHEVVARIQQETGLQAAAHLTCVGATRAEVDDVANHYWESGIRHIVALRGDPPE
GETQYFPHPDGYDYAVDLVAGLKRVADFEITVAAYPEVHPQAESAQADLDNLKRKLDAGA
TRAISTFFFDNDVFTRFRDRASAAGINAPILPGILPLAHFKQACKFAAINGTSIPSWLHE
LFAGLDDDPETRKLVAATFAAEQVRRLIKEGVSEFHFYTLNRADLAYAICHILGIRPKTV
K
>A0A6M5IZP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbiconiux sp. SALV-R1|TrEMBL
MSVTTELREACPKHMEYGPCGGVDFDGSCEVGAFRCVFLDLPTVRWKGGGEGPDENSPTA
PRHGASAMRDLLATRQVVVADFPGRALDRASLEECVDALAGRVDAVLAGDSGRSRVQFSP
AYRAHLIQQRGLPVWTGLNCRDRNRVALEGELAGLAEVGVAAVHCVTGDHTLTGDRPDAK
PVFDLDSTRVAALARRAGHLVSVGESPTTPPHDRRAARLAEKVRAGAEICFVNHAGGAEP
VRRFIAESRDAGAAPGFIACVPMVVDHGSAALLRSFTTLVLPEGFLDGILASSDPRRAGI
DAALVLSERLLELDGVVGVNLSGGAADGHEREFAEALAEVADRLQLGAPGASAASPKLTP
>A0A8D4N6A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus argentoratensis|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHADHPVYILGTIGGLAGDTDATVQR
ATPATIAANVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFVGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A1H8A8W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophus gentianae|TrEMBL
MSALQNILSRMAETPLIFDGAMGTMLYDKGVFIQTCYDDLCLTSPGLIREIHEQYTQAGA
EVLETNSFGANRIKLRSYGLAEKVADINRAAVRLTRQAAGQKLYVAGSVGPCTQGGQVIA
GPEILDVEAAFREQMEALTGEGVDLLLLETFSDLKELQLAARIARETEVPVLASFAVDEE
GETAAGTPAEKMAAALETDPNVDVIGLNCGTGPAGIYEALLKILPQVSKPVVVMPNAGMP
RTVGGRTLYLANPEYFTEYAKKFIELGVRGVGGCCGVTPEHIATAARAVRGLSGVRKHIE
IVSREPAPTQLQSIPTAEKSRLAAKMLSGQKVTSVEILPPRASDFSNMLAKVRRCHEAGI
DAINIPDGPRASARVSPMITALVILKEVGIEPVVHYCCRDRNLIGMQSDLLGGYAVGLAN
YLIITGDPPKLGNCPEATGVFDVDAIGLTKVIHNLNTGWDIGGSPVDPPTGILIGVGANP
CAVDMEREIDRYFQKIEAGAEFAITQPVFDVEALLRFLDRVEKYSKRIPVLAGVWPLLSY
RNAEFMNNEVPGVVVPEAILRRMAECATGEESRRAGIEIARTICTEVHDRVAGFQVSAPL
NNVEIALAVLGKSEV
>C6HED8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces capsulatus (strain H143)|TrEMBL
MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTWAVDLVKYIRRTHGDYFCIGVAAYPEGHSDESYPEVQDPVKDLPYL
IEKTRAGADFIMTQLTYDLGAYKRFEEMLRNHESGVFETIPIITGLMPIQSYHILTRTTK
LSHARVPPDIMARVEAVKSDDEEVKRIGVDILCEIVNGLKQVSYPGPRGFHFYTLNLEKA
VALTVEKCNLIPPLSPLPSDSETYMDTAVFMAQGKQNGISLLSKRRASSMNSQPHNRLIV
DRPSDAGGSSQASTTHETPALGAGMPALNPPPRTTTLQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVNAAVARRLWGYPTTKQDINNIFQRHVSGELHLVPWSEGGA
QDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAF
VEFFCPAHDFESILKPIFESHSHDEFAWFATNVAGDFMSSSPATDATTEDSSGPVDVFLD
SNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIFPRGSPTER
LLDQLKNDVWLICCVGQKYGAGCASLEAAEAEGKLLWKLLGGTGTGPDSVNNH
>A0A0U5L0J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia gerundensis|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRAIAQDYWDNGIRHIVALRGD
LPPDSGKPAMYATDLVGLLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPHWMTAMFA
GLDNDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPASALSA
V
>A0A5E7MXR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPSAPHMSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRALGVTIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQSFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1V4WXS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdus sp. PtaB.Bin047|TrEMBL
MTAPGNLERVLTSGGFAVTAECGPPRGADPESIRKKGGYLKGFVDAVNVTDNQTAVVRMS
SMASCLILKEMGFDPVLQMTVRDRNRIALQSDILGAAALGIRNILCLSGDHQSFGDHPGA
KNVYDVDSTQLIDMARTMRDEGRFSGGAEITVRPEIFIGCVENPFADPFEIRAPRLAKKI
SAGARFVQTQCVFNVEKFARWMEMVRDLGLHEKAYILAGITPMKSPGMARYMKNSVPGMD
VPDHLVERMASVPKEHHREEGMAICLETIERVRAIKGVAGIHIMAIEWEEIVPDVVKGAG
LRTRP
>A0A1R3XCR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter indicus|TrEMBL
MKVTEHFQNANGKTLFTFEILPPLKGENMKTLFNHIDPLMEFKPPFIDVTYHREEYVYKQ
RENGLLEKRSTRKRPGTVGICAAIQNHYKVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLVLRGDCVKSEQRFVPEPDGHTYATELIGQVVNMNQGCYLDEEQAYHNGTDFCIGVAGY
PEKHFEAPNLTSDLRWLKKKVELGAEYIVTQMFFDNQKYFDFVNRCRAEGINVPIIPGLK
PMTTKTQLTLLPSLFHVEIPCALADAIESCADNKAAAQVGVEWAIQQSKELMEFGVPCLH
YYSMGKSESVRKVAEALF
>A0A5Q0IS91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clavispora lusitaniae|TrEMBL
MSVVERIQALGPDEKFCSFEFFPPKTDAGFRNLLARLHRMRDLNPLFVSVTWGAGGSTSE
KSLELAVTCQQLLGISTVLHLTCTNTNKAIIDDALSRAKAAGIRNILALRGDPPRTREYW
TPECSFRTAVDLVRYIRAQYGDYFCIGVAGYPEGHVDGSDGAEQDPKRDLPYLEEKVAAG
ASFVVTQMFFDADKYVAFEKMVRASPVLKDVVLIPGLMPITTYKVFTRATKLSHASVPAA
VAEQLSSAAVDDDQVKKIGVDVLSQLVADVSARSAARGFHFYTLNLERAVAAIVESCPEL
RGSAARLSRSRASSDPFESDSETSAPNAGKVESVPDSVPLVRDRRVTLAATWDDFPNGRF
GDASSPAYGEIDGYGPSLKLEPPEAVAVWGTPQSVADVSRVFIDYLSAKISSLPWVSTEL
SPETALIQEQLFELNSRGLFTLASQPAVDSCPSSDSILGWGPRNGRIFQKSFVEFFVPKT
EWERLLRLMDKDISDKTITYFCGNSKGDITTNMPHKSSQRTAITWGVFPSKEVLQPTVID
RQSFQAWNEEAFGLWLDWARCYAPDSPSYRLLAGIHSDYYLVSIVHNNYLDENALWDTLL
Q
>A0A423N7W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A2E1IZ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIDYFEKANKTLFSYEIIPPVRGGSIQKVFDLVEKLVPFNPPFIDLTSRSAEVYFEEK
DGNKIKKYVRRKRPGTIGISSAIKNKFNIETVPHVLCNGFTKEETEDALIELNYLGIDNI
LAVRGDDLRFDRKGSNNDKVNKYASDLVVQVSEMNKGIYIENLLDSVASNFCIGVGGYPE
KHFESASLNVDIERLKSKVDCGADYIVTQMFFDNKVFFDFVEKCRNAGIKVPIIPGIKII
SLES
>A0A357HDC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
TADKTLEISKTINKYFGLEVMMHLTCTNMQVSSIKKVLIEAEENGLSNILALRGDPPEGS
STWDQHEDGFRYSVDLVRYIRKEFGNHFCLGVGGYPECHHEQSDLDADISFLKEKVDAGS
DVVVTQLFYDVDKFLFFRDKCIKAGIKVPIIPGIMPIHNYARFIKFTQFCQISIPDSVSA
QLEPIKYDDSSVINYGIDQATAMCQKLIENGVPGLHFYTLNLEHSVSAILKSLGFVSSPG
TXAI
>A0A7V8RL71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas brassicacearum subsp. neoaurantiaca|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VEFIREETGEHFHIEIAAYPEMHPQARNFEDDLRNFVRKANAGASSAITQYFFNADSYFY
FVERVRQMGVEIPVVPGIMPITNYSRLARFSDACGAEIPRWIRKQLEAYGDDTASIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A3P9DH30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maylandia zebra|TrEMBL
MVNQVQRGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMDPET
AGSRWSSSLHAHVPLCFFYRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY
CGLESILHLTCCNQSKEKITGYLAKAKHLGLKNIMALRGDPIGEDWEEEEDGFNYAIDLV
KHIRSEFDDYFDICVATPGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFLKFLD
DCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNYGIQQ
AVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSPSQTEGRRC
STIFWASRPKSYIYRTRTGTTSPMGKFLVSSFWELNDYYLFYLRLQNEESVFEVFTCYIT
AQPNRCGHKVMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPIVGL
SGFVHKASVTPWLCGRNLTNAPEMQPNAVTWGIFAGREIVQPTVVDPVSFMYWKDEAFAL
WIEQWGKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDDHHNIT
>A0A1F7NZ42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium RIFCSPHIGHO2_02_FULL_69_13|TrEMBL
MAMSPFLSRLAEGPLLCDGAMGTMLYASGVPLDGCFDVFNANNPTLVQSIHAAYLSAGAD
LIETNTFGANRFKLAVHGLDARVREINARGAKLARDVRETAGREAFVLGSIGPLGKYLAP
IGAIGVEEGRAAFREQAEGLLEGGVDAFIVETFSDLGEIRLAVEAIRALTDELPIIAQMA
FTDEGVTFVGRSAVEVARALRGLPVQVIGANCSVGSSVLYDILEQMLPEAGGLPISIQPN
AGLPSRVGERLIYLSSPAYMAEYAGKMLEAGARIVGGCCGTTPDHIRAMRAAVDRHVPTR
ARAGRVTVSPPAREEAPALRTTAVPTPLARKLEAGEFLVTVELDPPRGHNIEKLVQGAKL
LKERGVEMVDINDGSLGRIRMSVLPTAVLVREATGLDIIMHFTCRDRNLMGIQADLLGAH
AMGIRNILAIKGDPPRAGDYVNATAIFDVNAIGLIRIIQGMNGGLDATGNSIGEPTGFHV
GAGLNPAALDPDKELARLFRKVEAGARWAQTQPVYDLEVLDRFLSRAGRLPIPIIVGLLP
LHSFRHAEFLHNEVPGITIPDAVRARMKEAGDRALRQGIEMAQALLQQIRARYAGAYLMP
SFGRYEVVAEVLDALR
>A0A6L5XMU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio porci|TrEMBL
MQIGSLIQAAKAPFFSLEFFPPSDETHLPSFYATVEQLRALTPLFVSVTYGAGGARRHNT
LAVTAELARRGFTTMAHLTCVGAEPESIAAFLRELRAAGVDNVLALRGDPPMNGHWDWKD
GYFQHAADLVSFTREHEPDMGIGVAAYPAPHPESPSFALDRRYTADKLRAGADFAVSQLF
FDVREYEALVADLRARGLDTPVVPGILPIQSFDSLRRVLSLCGATIPGKLYLSLEEADRK
GGAEAVRDAGLDFAVRQICQLLECGAPGIHLYTLNKGDLCLQIAEEVGM
>B9M1X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geotalea daltonii (strain DSM 22248 / JCM 15807 / FRC-32)|TrEMBL
MNFLQALQHEVLIGDGAIGTMLYAKGVSPDANFEHLNLVRPSLVLDLHREYVTAGARVIE
TNTFGANFAKLDAIGIGAKLHDINVKGAQLARQAASGRDVYVAGSIGPLVGAKGEEKDLV
EDQIRRMFDAQVDALVEGGVDLFLLETFSDLRQLEIGVAVAKKTGLPVVASMAFGENSRI
AGGIPVESVAERLAAAGADVIGANCGAGPLEILRTVKRLGKVTALPIAVYPNSGFPEYVN
GRYLYRATPEYFAGMAEEMAAAGAVLIGGCCGTTPDHIREIAAKVKGRKPAQRQISTSVP
LAESGETRAVAAPGFLSSWGKGPVVTVELDPPRGLDCSNVLTGSRILKEAGADAINLAEN
PLARVRMGNIALANLIQREIGIEVIVHITCRDRNLLGLQSDLMGASLLGIRSILAVTGDP
ASLGEQAGASSVFDLNSFTLIKLLDDLNRGVNALGNPLGGGTGFTIGAAFNPNTARMDVQ
TGRLLKKVTNGASFAQTQPIYDLKRLDDMLEQTAHLNIPILPGVLPLVSERNAEFLHNEV
PGIVIPEEIRGRMKGKEKEEGAREGLAIAREFIDAARDRVGGFYLIPPFGRHGIAAELVR
YIKGIGE
>A0A7Z1HCL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pseudomycoides|TrEMBL
MKLLDLLQRGIVIGDGAMGTLLHSHGLQSCFEELNLSEPERIISIHKQYVAAGADVIQTN
TYGANEGKLRMYGLEDRVRKINRAAVRHAKAAVTEKNAIVGTIGGMKHIGAVTTNDMERE
FMLLEQANALLEENVDGLLLETFYDEFELLHAVKVLRKQTNVPLIAQLALHSAGTTQNGN
SVDDVLKRLIEYGANVVGLNCQLGPLHMIESFKTIAIPEHGYLSAYPNAGLPKYVEGRYV
YEGSPAYFEEMAPKFIKQGVRLLGGCCGTTPAHIEAMKRALENERPITAKEVVKHVEVIA
TKRVNTVDRITLVEKAKKETTVIVELDPPKTLDTQRFFEGAKALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLAALGMEEVLALTGDPARVG
DFPGATSVYDLSSVELIKMIKEMNNGRSILGKTIGAATRFSVGGAFNPNVRHIEAAVKRM
EKKIAAGAEYFLTQPIYDAAVIRSVYEATKHIEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEQVRRRMDGHRTSEAAVIEGIRISQELIDVAMELFNGIYLITPFLKYEVTEALVKYIQ
TKKEQKEGMNV
>A0A7G8EHV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. BMK-MC-1|TrEMBL
MSSALQQSLEAGSITITAEVMPPRGGDPAHTIAMAECLRGRVHAINVTDGSRAVMRMCSL
AVCRLLLDHGLEPVLQMAGRDRNRIALQADLLGAHALGIRNVLCLTGDPVRAGDQASVRS
VHELESVRLLQQVSAFNRGEDPVKDRLVDGPTNLFAGTAADPHCASWSGLSRRLARKREA
GARFVQTQMVMDPHALERFCRDLADPLELPVLAGVFLLKSARNARFINRMVPGACIPDHL
IDRLDQAKDPMAEGIAIAAEQVRQFTGIAQGVHLMAVKAEQRIPEVLDRAGVSLPVQ
>A0A4V2J1Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Obesumbacterium proteus|TrEMBL
MSFFHANQREALNQSLAELHGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGGGKPDMYACDLVSLLKEVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEVHSPI
IA
>A0A0C2Y646|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus badius|TrEMBL
MKLLDRLQTEVLTADGAMGTLLYSYGIDFCYEELNVEKPEIIEKIHRDYIQAGADIIQTN
TYSANALKLARYGMENRAEELNKAAVRIAKKAAAPEQRFVLGTIGGIRGIRKSSASLSEI
KSAFQQQAEAILQESPDGLLLETYYDFEELTTVLQLLRKVTDLPIVSQVSMHEPGILQNR
LSLNEAFKQLESLGADVVGVNCRLGPYHTIQALEEVTLPEKAFLSAYPNAGLLDVEDGRV
VYESEADYFGQAAVQLRNEGVRLIGGCCGTTPKHIEAAKKALTGLAPITEKKVIAQKPIV
IKEPAPLVVPPLHEQVKKERTMIVELDTPKHLDTAAYIKGAKALQQTGMAAITMADNSLA
SPRVSNLAMGSLLKVQHHIRPLVHITCRDRNLIGLQSHLMGLHALGLHDVLAITGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGISFSGKPLKQKANFSVAAAFNPNVRVLDRAVKR
LEKKIACGADYFITQPVFTKEKIVEIYEATKHLPTPIFLGIMPLTSSRNAEFLHHEVPGI
KLSEETLTRMKVYEHDKEAAAREGVTIAKELIDTAAKLFNGIYIITPFMRYDMSIELIRY
IEELDGKTKERGIPHAETISN
>A0A7M1PWQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. 'deep sea'|TrEMBL
MFIKNMFAQKKPVVSFEIFPPNKQSKINTIYNTIENLAVLQPDYMSVTYGATGISEGKDL
TVKLASFIKNEINIEPLAHLTCIGSTQQQVYQQLATMKQVGIDNVLALRGDKPIDYLQNN
SSYFNYASDLITEIKNNFQFSIGAACHPEGHIEAKSKITDLINLKNKVDCGADFLVSQLF
FNNQDFYAFLNEVRLLGINIPVVAGIMPVVNTKQIERIVSLCGANVPQKFKKIMVKYQYN
KEALIDAGIAYASEQIIDLLSSGIDGVHLYVMNRPYIAKRLINNISSVVKVLNTKEEEHV
S
>A0A6M5DBX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kosakonia sp. MUSA4|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAVPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCAATGIDVEIVPGILPVSNFKQAKKFADMTNVRIPAWMSQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A1C5ZDF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MKIKQMFEKGTVFSFEIFPPKKTSSIDTIYNTLEQLRDLKPDFISVTFGAGGSSNNNTTC
EIAQTIKEKYGIESAAHLPCINYTKEEIVKILGEFKKHGISNILALRGDINPDIPPKSDF
KYASDLIAFIKQHGDFDIAGACYPEGHMETDNLVTDVLNLKKKIEAGAEHLISQLFFDNS
YFYSFLERTQIAGIDVPIEAGIMPVTNKGQIERMVSMCGASLPSKFSKMIQKYEHSPEAL
RDAGIAYAIDQIVDLVSNGVDGIHLYTMNNPYVAKRISEAVESIIRS
>A1WXM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halorhodospira halophila (strain DSM 244 / SL1)|TrEMBL
MESQKKHPRVFSFEFFPPKTDEGAENLKGTRERLERLNPAYFSVTFGAGGSTQDRTFETV
IDIQRNSTADAAPHLSCIDASRDRLKQMILDYKEQGVKYIVALRGDRPSGSGSMGQGELS
YANELVELIREVTGDHFYIEVGAYPEFHPEAPDALTDIENFVRKAKAGADSAITQFFYNA
DCYYRFVEDCEKRGVDIPIVPGIMPLMNFEQQARFAAACKADMPRWLAQRMEAWKDDPQS
RMEYGIDVVTRLCEDLLDNGAPGIHFYALNKAPVVERIWHNLGLSEQTGGEVRKPDEVEV
PAQP
>A0A2E9ZWV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nevskiales bacterium|TrEMBL
MSELQFSFEFFPPKGEKGATRLAEVRKQLAALQPAFFSVTFGAGGSTQSGTLETCIATKQ
DTGCDVAAHISCIGSTRERISQLLGEYRQAGINRLVALRGDLLPGMTDPGEFRYANELVS
FIRETTGDEFHIEVAAYPEYHPESPTPDADLDNLVRKVQCGADAIMTQYFYNVHAYEDLV
ERLAARGVRVPVVPGIMPITNHDQLIRFSDRCGAEIPRWIRRRLEAFGDDSESLRAFGLD
VVAQLSRNLLDLGAPGLHFYTLNRAAPTLELWQALRLPMPAAA
>A0A0E2YZT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosococcus oceani C-27|TrEMBL
MQPQQNNPLIFSCEFFPPKGEENASKLRRVRRKLARIHPRYYSVTFGAGGSTRDRTFETI
LEIQAAAKETGIEAAPHLSCVGSSRKSIREVLQAYQHQGVKRLVTLRGDLPSGMVDPGDF
HYASQLVEFIRAETGDYFHIEVAAYPEVHPQARSAQADLINFKHKVEAGADSAITQYFYN
VDAYLRFVERCKSVGIDLPIVPGIMPINNYVQLARFSDACGAEIPRWLRKRLEDFPDPAT
MSAFAIDVVSDLCYRLLEAGAPGLHFYTLNRADPTLAIWDNLGLETQPANLSAVTKI
>A0A7V7Z4L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. B1-WWTP-T-0.5-Post-4|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYADGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>D6TL89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ktedonobacter racemifer DSM 44963|TrEMBL
MRRTSPFIERLVQGPILCDGGMGTQLYARGISYERCFEQLNLTSPELIKTIHLEYVAAGA
EIIETNTFGANRFRLREHGLEEQVHAINRAGAKIAREARELSEQPIFLAGNIGPLGSHLA
PLGDITPEEARNAFQEQAAALLESGVDLLIIETITNLEEMREALSAIRGMTDLPIVALMS
FDEENTVSSGEEPLLVAQTMQELGADVVGVNCALGPAGTFSVIEGMSTGEHEHFLLAAQP
NAGLPKRVGNRFIYGASPDYFADYARRFLEIGVSLLGGCCGTTPQHIAAMRKVLAEYAPE
LGTREITVPKRQPRLETIFERDPESSSGTQTHSTYLSQRLATGHFVVSAEMRPPRSVKFT
RFLQNAEYLRDIGVDTINITDNAMARVRMSNVAAARLIQQQVGVETIVHFTPRDRNLMAV
QSDLIGAHATDIRNVLAVTGDPPTHGDFPNATGIWDVDSIGLIAILNNLNQGLDGRGRKL
GTPGSFCIGCAATPPATDIALDLERLHRKIEAGAQFIMTQPVYDPETLISYFERYKQEYG
PLTIPILVGLQPLHSYQQAEKFHNEVPGIVIPEAVRERLRLAGDQACDTGLEIIKELFDA
TLPYIQGTYIMPLDRYDLVGELLPYIRQQTVDRGSESAISS
>A0A7C1LM45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter sp|TrEMBL
MKVTDHITNAKGKTLFSFEIVPPVKGRNIQELYKNIDPLMEFRPPFIDVTTSREETIYVK
KEGLLDKKTTRMRPGTVGICASIQHKYNVDTVPHVICGGFTREETEYMLVDCHYLGIQNV
MALRGDARSEQKYFEPTDGGHPFAINLVKQIQDLNCGKYLHESIESEHCSEFCIGVAGYP
EKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEAARNIGITVPIIPGIKP
IAVKRHMQLLPQVFRIDMPQDLIEAVDSCATNKDVRAVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAEALF
>A0A2N8HQU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia muciniphila|TrEMBL
MHLRERLQSGAGPSLSFEFFPPKNEQAAAALYQTIRELEPYHPSFVSVTYGAGGSTRELT
REVVLRIQHESRIPTVPHLTCVGHSREEVWSILDQYAQAGVRAVLALRGDPPRGTENYNR
DADAFRHAAELVAFIREYNESGRHPDPDGFAIGVAGFPEGHPSTPNRLREMDFLKAKVEA
GADYICTQLFFDNHSFLDYRERCLLAGIKVPILAGIMPVTSLSGMNRMAELSGGTCFPAR
LLKALKRAGSNPDAVQEVGIQYASSQCAELLDSGVDGIHFYTLNQSRATRQIYRNLGLKD
SLQLLEHGEDK
>A0A1V5E5M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophus sp. PtaU1.Bin208|TrEMBL
MTVTWELVPGRGAREKAQETVLLEAEKAARGGKIQAVSLTDNPGGQPALMADSLACEIKA
LGIEPLVHFTCKDKNRSQIESQLYALERAGVRNLLVMSGDYPVSGFMGRPQPVFDLDPTH
VLALIRDLNNGLEYPLPKGTGKLQTGHFFAGAAVSPFKQTEAELLGQYYKLKKKIDSGAS
FVVTQLGYDIRKFQEVLLYMKRRGIEVPVLGNVYILSYPVARMMKENRLPGCVVTDELLA
QLDQERSLPDKGVEARLLRAARMYALLKGLGFSGAHIGGHLVTYEQVEAVIEKGEELSAS
WEALIREFQYPLPGSFYYFQGDPYTKLNQFAPASRQGLSTDVADKGLYGFSLFVHNLFFE
PGRKGFALMRLFARKLKGTPLANLLHKVEHLLKTLFYECRDCGDCALVDLAFLCPMSQCP
KQQRNGPCGGSYQGWCEVYPGRRRCIYARAYTRLKSRHQENQLEEIPVPPCNWELNSSSA
WLNFFLGKDHTAKRLGISELPDKPGHSG
>A0A6P5N7S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachis duranensis|TrEMBL
MKVIEKIRAAAAADPDRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGS
TADLTLEIANKMQNMVCVETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQ
DKFVQIEGGFACARDLVKHIRAKYGDYFGITVAGYPEAHPDVIGSDGLATPEGYQNDLAY
LKSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCK
TKIPADIFAALEPIKDNEEAVKSYGIHLGTEMCKKILAHGIKTLHMYTLNMEKSALAILM
NLGLIEETKINRSLPWRRPANVFRVREDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSR
NPSYGALTDYQFMRPRARDKKLVEEWVVPLRSIEDIYERFKQYCLGKLRSNPWSELDGLQ
PETRIINEQLEKINLKGFLTINSQPAVNGEKSDSPTVGGGGPGRYACSKGVCLG
>A0A6A6RM81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massarina eburnea CBS 473.64|TrEMBL
MHISEKLALSRAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHDFGPTFIDVTWGAGGTLS
HLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDDALKEAKLAGCSNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIRERYGDYFDIGVAGYSEGCDDNEDVDELIDHLKEKVDAGATF
VVTQMFYDTDLFLEWVAKVRAKGIDIPIIPGIMPIHTHAAFLRRANWTRCNIPKHWTEAL
EPVKNDDVEVRAVGRDLVAEMCRKLIDAGILHLHFYTMNLAQATRMVLEELELLPDLESP
LQKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDARSPAFGELDA
YGVGLKGTNAQNIKLWGSPESIQDISDLFVRYMSGKLDSLPWSEAPISNEADTLTKDLID
LNRRGFLTINSQPAVNGAKSSHLVYGWGPRNGYVYQKAYLETLVSPEHIAELITRIERDP
GMTYYAVNRDGDLKTNTPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYKVGKEW
ANCHSSVSPSRYVIEDVMDTWYLVNIVHNDFHIDHGIFPLFEGLQVADMDKPLHRLEVPN
GNATNGAPNGESTTNGQKSTLNDLVDAAKSAAETVTQGINGLAVSSN
>A0A5M6CAR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kwoniella shandongensis|TrEMBL
MKITEKLQKAEREGRPFWSFEFFPPRTAQGLQNLYDRIERMRNLGPEFIDITWGAGGKNA
DLTNSLVQMCQETIGIETCMHLCCTEMPKEKVEWALAQAKAHGCQNILALRGDPVAGTSQ
WEPTPGGFMNAVDLVRHIHKYYPGDFCVAVAGFPQGHPETKDAPDAQEQEIAWLKEKVDA
GADFIFTQMFYDTTIFFDWVKRVRDAGITVPIIPGIMPIQNWEKFEKWVQRENIVVPPHF
YEALTPVKGDDEKVRKVGTKLVGDMCKAILANKEAGVKGLHIYTLNLEKGARMLLEELGF
EGRREQIAPLPWRPSLTPHRRGETIRPIFWANRVESYLSRTDEWDEFPNGRWGDSRSPAY
GDLDGYPVSINISPNDAYNLWGHPTTFEEICTLFARFCRGDLGKLPWSSQPPASETSVID
DQLAKMNELGYLTINSQPAVDGARSDDKVHGWGPTGGYVYQKAYLEFFVSPELLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWANLYPESSPSRKLITDTMSTSYLVNIVANDFQDGLSIFEPFLLDQQPIVGKLVDG
VKGAVNGVLEGVNGAVEGIKGKVVQTGFSAGVLTNGNGNGH
>A0A4S2W599|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. LRa12|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTNFVD
KCRAGADYAITQMFFQPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A364L6X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces amestolkiae|TrEMBL
MEKITEKIAALPPDSNYFSLEFFPPKTQMGSVNLQARLERMAQALRPLFVTVTWGAGGTT
AAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIRNILALRGDPPRSEE
YNMDGDDDSNKDFTWAIDLVRYIRKTYGDYFCIGVAAYPEGHPGESQTDIQDPEKDLPYL
VEKVQAGADFIMTQLTYDFEAYQTFEDRLRNHPSGAIKTIPIIPGLMPIHGYKILTRVTK
LSGAHIPPAIMSRIEQVRSDDERVKQVGVDIVSEIANQIKALPNPGHRGYHFYTLNLEKS
VTLILERCDLIPPSSDDNAIEDGIAIEEVDSTNKDLKTLVSRRRASSINSGPHNRVIVEK
LHVPTDQQSEHSSRKSITYETLASSAGVPALNPPPRSTQLQISEGIGSLGREATWDDFPN
GRWGDSRSPAFGEIDGYGPSLHVNATVARKLWGFPVSREDIGTLFRKHVSGELYIVPWSE
GGAAEDANLNAETQIIKPQLLQIIEKKNWWTLASQPAVNGVRSDHPIFGWGPPGEGFVFQ
KSFVEFFCPNSDYQNKVKPTLLRHGSEEFSWFAINAAGHLESSFLLSASSSPQPEDASSA
IAADEEPLEIRESTGMAVTWGAFRGREITTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRG
SATERFLNETKNDVWLLCVIGHRYGAGTKPGSEEEKAEMNTLWNVLAGDM
>A0A258T9I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 35-66-30|TrEMBL
MQFDAERREDPRHEVAPAARSDAKALAMLVERLSIEVSPKEVLHSGHALGVPAGTRTFIT
RLPRGSLEDTRAAAVALRQAGLQPVPHVAVRTVPDAGTLERWLRFFVRDAGVEEILLIAG
SQERPLGAFGETADTLASGVIEGSGLRAVSFAGHPEGHPVADADELQRAIDVKNEFAART
GLSCALVTQFFFDATPVIAWERRLRERGNRLPIDPGLHGVTGVPSLLKHALACGIGASVK
ALSAHGSGGILQFAQIRTPDALAQALAAALANDPDSLFRGFHLFPLGGLAKTVDWMAQVQ
RSAAGTSLAEGVPGAGAEDGIARPPQ
>A0A8J6UEM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vulcanococcus sp. Clear-D1|TrEMBL
MGLQQALEVGSLAITAEVMPPRGGDASSTMAHARALKGRVHAVNVTDGSRAVMRMSSLAV
CRLLLDQGIEPVWQLACRDRNRIGLQADLLGAHALGIRNVLCLTGDPVRAGDQPGARPVN
ELESVRLLQQLQAFNRGEDPIGGTLADGATALFAGAAADPQSPSWSGLKSRIARKHQAGA
RFLQTQMVMDAECLKRFVGEITGPIGLPVLAGVFLLKSAKNAAFINRVVPGANIPQSIID
RLAAATNPADEGISIAAEQVATYAGIAQGVHLMAVKAEERIPLILERAGISSRC
>A0A0S1YRA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas stellipolaris LMG 21856|TrEMBL
MVSYAQGVDALNQSLSELRDIDVSFEFFPPKSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELRQIAQDYWDSGIRRIVALRGDLP
PGVKDTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIS
QFFFDTSVFLRFRDRAAAAGIDLDLVPGILPVTNYQTLVKFAGFTNVHVPGFLHKMFDGL
DDDDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRAG
>A0A2G0V767|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Tremblaya phenacola|TrEMBL
MKNLPNISFEFSPPKTYYGFLKMLQTQKELACVLPRFVSITYSRSSFKRNQLDLIVSMKR
FFNSVVPHILCTSPKQELMKELSFYKAVGIRHVVVLKGDTPGLKEDSFSTDASDLVRLIR
SVHGELFYIDVAAYPEGHPGNPSILKDIKSFVRKVEAGADSAITQYTYSADSYYKLLEDA
YKLGVKIPITPGIMPIVSYDKLVYFSDLCGADIPYWIVKRLKTLKDRSCSVLEFGVDVIL
KLCENLISLGVSDLHIYTLNECAVVKTICKHLGYIQ
>G9YDJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hafnia alvei ATCC 51873|TrEMBL
MSFFHANQREALNQSLAELHGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGGGKPDMYACDLVSLLKEVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEVHAPI
IA
>A0A3M2JWD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. NEAU-YY56|TrEMBL
MELTMSSRDTPHPLDAHAVADGLGAVDRPTVSFELFPPRNPDAAPRLWATVQELAAARPD
FVSVTYGASGSTRTTTRQLVRRLLRETSLTPIAHLTCVAASADDLARTVEEFLDEGVRSF
LALRGDPPADGSWAPHPEGLPTASALVALLRDVERRRCASSPAQAVRAATRPLSVAVAAF
PRGNAGSGSSREQDVAALLAKQQAGADFAITQVFYDVADYCELVALARDAGVTIPVVPGI
IPTTDPARLRRVAQLTGVPVPQRVLDVLDAFDADEPADVARRHRAGTRMGVDLVNGVLDG
GAPGVHLYTFNTHGPALDLLDGAGLGGDAPRAHSRVTPAAPDLLTVPTT
>A0A0B8T7Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium deserti|TrEMBL
MKIVDHIKNAKGNPLFSFELLPPAKGQGIKSIFSTMDELMEFKPPFIDVTYHREDYLYKQ
HDNGLLERVAYRKRPGTVAICAAIMSKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDPDFIPTPGGHAFATDLLQQVVDMNQGQYLHEDIESSAKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVNKCRENDIHVPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSDAVENCKTNADVRQVGEEWLVHQCKELIKFGAPVLH
FYTMSNPGPTKKIVERLA
>A0A345HL19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces paludis|TrEMBL
MALGTASTRSDHAPTVRELLASGKTSFSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTREGTVRATERIAADTTLTPVAHLTAVGQSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIKHPKGVRYAAELVRLIKESGDFCVGVAAFPEMHPRSPDWDTDIRHFVD
KCRAGADYAITQMFFDPEGYLRLRDRVAAAGCATPIIPEIMPVTSVKMLERLPQLSTAVV
PPRLKERILAVREDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYENLG
LHAQS
>A0A1I4AKH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sacchari|TrEMBL
MTETTTRRRAPRSTRDILRTISYEIMPFRGTEDAVLEHVPVDVPLTVTVTEAKGIETTIA
LAANLTARGYRVSPHVAARMVRDTAHAKDLAAQLTEAGIDRVFVVGGDAPVPAGEFTEAL
DLLRVFAETGMFTRTGIGGYPEGHARITDQDLDAALTAKAPLATHVITQICFDARTTVDW
ARRVHRGHPDLEVVIGVPAPVSRQKLVRIAGGIGLGQSARFLRKQQNTIWKLIRPGGYRP
DKLLRAFEPHLAAPDVNIAGIHLFTFNELAGAEAWRRSLLARLDAG
>A0A127GYN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. P11G5|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPTYFSVTYGAGGSTRSRTLDIVQALCA
RGETDIAPHMSCIGDDKTEIAELLTHYKSLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFEFDIDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTVVQPLVAGIMPITNSSNLMRFADSCGADIPRYVRKRLTDFGDDRKAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVEALGLTSQI
>A0A2N2J0X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-13|TrEMBL
MRENLFKEALLNPDTFPVTWELVPGRGAREAAQEKAMALAKQAAVGGKIQALTVTDNPGG
TPAMSADFMGSEILKMGIEPLVHFTCKDKNRNQIESQLYALDRAEVRNLLVMSGDYPVSG
YQGRPAPVFDLDPIHTLQLVSEMNRGLEYPGIKGTVRHQPSDFFAGAVVSPFKATEAEQV
IQYYKLKKKIHAGARFIVTQLGYDVRKFHELILFMKLNGFDIPLVGNIYILPYGAAKMMN
RNDLPGSVVTDKLLADLDRERSDPDKGEGARILRAARMYAIMKGMGFSGVHIGGHNIKYE
QVEEIIRQGEELTAQWTGLIRYFDYPMENGFYYFERDPETGLNKETPEKRQGRPLDAEIE
CTYGFSRLSHKLMFEPGKKLYGIMNRLSRKVAGTKMEGLFHKLEHLTKVMLFDCKDCGDC
ALIDVAYLCPMSQCPKNQRNGACGGSFKGWCEVYPGKKQCVYVRAYARLKKYGEEAQLEK
SIVPPCNWDLYQTSAWINFHLGKDHTSKGQGRR
>A0A7K2M0T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5998|TrEMBL
MALGTASTRTDRARTVRDMLATGKSTFSFEFWAPKTEKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVTAAGCETPVIPEVMPVTSVKMLERLPQLSNAVI
PDALKERILAAKDDPTAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A7W2VFB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. RHBSTW-00325|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIARDYWQNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A2M7SKK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_10_14_0_8_um_filter_43_12|TrEMBL
MVSSFKKALESGKFVVTSEVAPPKGTNLEKMVHHIELLKDKVDAINITDHQSSVMRFPSL
GGALLIKEMGGEPILQMTCRDRNRLALQADLLFASSRGIHNVLCLTGDSVLLGDHKEAKS
VFDLDSSQLLAAIRRLERGKDLAGNDLDGGISFCAGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVYDLDRFKQFMDYARQFPAKILAGIILLTSAPMARFMNKNVAGVNVPQEPID
EMASAPKGRAIEKGIEIAGRMIMRIQEERMCDGVHIMAIGREELVPDIMAAARLV
>A8ZXJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfococcus oleovorans (strain DSM 6200 / JCM 39069 / Hxd3)|TrEMBL
MSEKTPSRLEKILRQGHLAVTSECGPPRGSDPAAITKKAEMIKDYVDAINITDNQTSMTR
MSSLASCIHLKLMGLEPVLQMVTRDRNRIALQSDILGAASFDIFNMLCLSGDHQSFGDCA
TGQNVHDIDSMQLLQLVRRMRDEGKFLGGDDIARPPRMFVGAAANPFADPFEIRVPRLAK
KIAAGAEFIQTQCIYNLEKFEEWMKRIRDRGLHEKVFILAGLTPMKSAGMAKYMKNRVPG
MDVPDEVVKRLSDTPKDKQAEEGIKMCIESIQRLKEVEGVRGFHIMAIEWEEKVPEIVQQ
AGLYPRPSV
>A0A436KWL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.002.04.1.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A4Q0RV75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium nanningense|TrEMBL
MTDLTIPARTDGQDGHLTRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHATIARILKETTLLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPAG
GIGTPYASHPDGYQSSAELVAGIKKRHADMEVSVSAYPEKHPEARDFDADIDTLKAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A8J3VTY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rugosimonospora africana|TrEMBL
MPGGPASVGELIGGREPTFSFEFFPPRDEQQERQLWQAIRELEPLHPSFVSITYGAGGST
RDNTVAATERVATETTLLPMAHLTAVSHSVAELRNVIGRFAGAGIRNVLAVRGDPPGDPQ
GEWVRHPQGVLYAEDLVRLVKEAGDFCVGVAAFPYKHPRSPSVEADTEHFVRKCRAGADF
AITQMFFDADDYLRLRDRVAEAGGRTPILAGIMPVTSMRTIERAAVLSGAPFPPALAAQF
ERISDDPVAVRRLGIEQASLLCERLLAEGVPGIHFITLNRSTATREVWQNLPMGVRI
>A0A7C1CR36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVIDILNNSKSTLFSFELLPPLKGHNIETIFATIDKLLPYNPAYINITYHREEVVYMPN
ENGKQVPVKVRRRPGTIGLAAAIQQRYAIDVVPHIICGGFDSHETEDALIDLDFLGIHNI
LAVRGNADKITGRFKPRTGGHRYAIDLVKQVTDLNRGVYLEKLMEKPKPTNFCIGVAGYP
EKHPESPNCESDIHYLKKKVEAGASYIVTQMFFDNKLYFNFVDKCRKAGIAVPIIPGLKP
ISIKEHLSILPRVFDVHIPQALVLELEKCKTNSQVARLGVEWAIEQSKELKNSGVKAIHF
YTMGKADNIARIAQAVF
>A0A7W0WEG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacteraceae bacterium|TrEMBL
AREPAGPYASAFELLDAMSQLEHGVEEVGIGGYPEGHPLIDDKELDRALGDKQPFASYVV
TQLCFDADTILGWISDIRDKGIVLPVYVGLPGAVDRKKLLQVSLKVGVGDSVRFLKKQSG
LVGMLLKPGGYSPDEQLERLAPYAGDRHYDIAGLHLYTFNQVERTEQWRQRMLGPQKASG
AGALQ
>A0A0M9DJK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus macroides|TrEMBL
MGLLERLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQKPELIEKIHREYIAAGADVIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLEEI
LAAAQEQATVLLAGNPDGLLLETYYDFEELTATLTMLRAKTDVPIIAQVSMHEPGVLQNG
ISLNEALHKLETLGADIVGVNCRLGPHHTIQAFEGVELPEKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVALRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVSEKHAKPTKIEI
VREAEPAKYESLYEKVKRERSVIVELDTPRHLEIDGFIEGAKQLYNAGADVVMMADNSLA
SPRISNIAMGALLKETYGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDVLAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKIVEIYEATKHLQAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSEDALTRMKTCGDDKERATREGIAIAKELVEVATQYFNGIYLITPFLRYDVTLELMKY
IEQLDEQKKGVSIDG
>A0A7W1D1D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacteraceae bacterium|TrEMBL
MAEFLRHPGYEVIPLQGTEESVVEHVPKDIALTVTASPGKGTWATVELAERLAGHGFGVA
PHLSARLIRDRLELGEILRRLRGAGIRNAFVVAGDIDEPAGEFEGATGLLEAMSEIGHDL
DEVGITGYPESHPKISDEMTIQAMYEKVPYATYIISQICFDPEVTSDWARRVWLRGVKLP
IRIGMPGYVNRQKLMRISAGIGLGESARFLHRQRNWLLKLFMPGGYSPGRLIEGLKPGFA
DPESNIQGLHIYTFNELEQTEAWRREMLQRAEPSA
>A0A7J6RQP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perkinsus olseni|TrEMBL
MARLIDKIQDRWDHDRDNGESTRVPFFSFEYFPPKTDMGVQNLYERLDRMAELGPMWIDV
TWGAGGSTSCKTFEICRNALTYHGLDVMMHLTCTDQPVKEIDEVGIRNILALRGDAPMHS
SEWKACQGGFSHAVDLVRHIRGKYGDYFCIAVAGYPEGHLEAESMEEDLAHLKEKVDAGA
DLIITQLFYDTEVFFNFVAAVRALGIQVPIFPGIMPIQSYSGFKKMTEFCKTKVPRAIAD
QLEQVKGDDQKVKDLGVEICVAMCSQIMSYGVDHCHSSGGLHFYTLNLESSVSRIIERLM
MVDSHVATRALPWRPSKASSRQEENVRPIFWSNRQKSFIQRTSCWDEFPNGRLGNQASAA
YGDFELNFRSYSKETQDKVAADRRRMWGDHVPNGDHVRRVFTAFIKGEVKRLPWCTESPT
EETLFIQKQLIRLNQCNMLTINSQPRVNGALSTDPYVGWGPGGGFVYQKAYVEFFCPESQ
LEQLVRGIEGEKYESISYMAVTADGSKVKSNIPPQGQVNAVTWGVFPNSEIIQPTVVDVT
SFMAWKDEAFALWNEWMDVYPEDDHQSRQVLSFIRDHYFLCTVVDNDFVAGDLFSKLTKI
CTPIPWETLRIENPSESDGHEVPETSLAVIAEVYSPRPKPTDLSPRHEPKDDITSFAPL
>A0A8I2A8F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MHVCEILSKTNKTLFSFEILPPLKGGSFNDIFNSIEPLLEFKPAYINVTYHQEEVVYKDR
GNGLVEKMVVRKRPGTVGIAAALQYTCNIQVVPHIICGGFTREETENALIDLSFLGINNV
LVVRGDPDRSQKTFIPEPDGHIHSLDLVKQIVDLNHGKYLEEDLQNSNPTNFCIGVAGYP
EKHPEAPNKASDLRYLKMKIDAGASYIVTQMFFDNRKYFDFVDNCHEIGINVPIIPGLKP
VAICQHLHLLPRTFGIDLPDDLAKELEKCKTSQEARNLGIEWTIHQTRELIAAHVPAVHF
YTMGRSDNIYRIASACF
>A0A7H1RUT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus zalihae|TrEMBL
MGLLDELKQRILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLARQAANERAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKEQLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACSGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A7X9HJ59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVTEILSHSKETRFSFELLPPLKGSSIQVIYDAIDPLMEFNPLNINITYHQSEVEYRRL
PGGLLEKRIIRKRPGTIGIAAAIMNKYQVMVVPHLICGGFTREETEDALIDLHFLGIRNI
LALRGDPQKGEKYFIPEEGGHAHNLTLVEQIINMNRGIYLDENLKNAIPTDFCVGVAGYP
EKHFEAPNMEADLRHLKAKIDAGAEYIVTQMFFDNRKYFDFVERCRKSGINVPVIPGIKP
INTLRDIELLPRTFHIDLPEELVREIQKCKTNQEAKEVGIEFCIAQSKELVKAGVPAIHY
YTIGVSDNIRKIAAAVF
>A0A0D0Q8M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus thermarum|TrEMBL
MGLLDDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIDAGAEVIQTN
TYGANYVKLARYGLQDDVKKINEAAVELAKRAAKGRAYVLGTIGGLRSTNKSTISLEEVK
RTFREQLYVLLNEGVDGLLLETYYDFEELQTVLSIARKETTLPIIAHVTLHDIGVLQHGM
PLAEALTELERLGADVVGLNCHLGPYHMLRSLEEVPIPTRAFLSVYPNASLPQYRDGRFI
YETSEQYFEETARAFREQGVRLIGGCCGTTPKHIAAIARALSDRTPVYKKEVRQRHTIIV
QEEKQTTAPSLADIARTRRSIIVELDPPKKLGLTTFLEGAKALKEANIDALTLADNSLAT
PRISNVAVGTIVKQQLGMRPLIHITCRDRNLIGLQSHLMGLYTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRL
EKKIECGAHYFLTQPLYSEKQIEDVYEATKHLPTPIYIGIMPLTSARNADFLHHEVPGIT
LSDDIRNRMAMCANDRVQSTKEGLAIAKALIDAAFDLFQGIYLITPFLRYDMTVELVRYI
HEKERLAKERTVYYG
>A0A7Y5A397|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MQSFLKVNEAIEKSDKTLFSFELLPPLKGQNIEHIENTIDPLMEFKPAFVNVTYHQEEFH
YKQLGNGLLEKKTIRKRPGTVGITAAIMYRYGFNVVPHIICGGFNQEETENALIDLHFLG
VKNLLVVRGDAQPSEKYFRAEPGGHLHSIDLVNQIMNLNKGKYIEEDLLNATPTNFSVGV
AGYPEKHIEAPNLDSDLKFLKMKIDAGAEFVVTQMFYDNKRYFDFVDRCRQIGITVPIIP
GLKPISTLNHLNILPQTFNIDMPQELVKEVQKCTDNKQVRRLGVEWAIAQSRELIAKGAP
VLHFYTMGNSDNIRKIAEAVF
>A0A0L6W3D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermincola ferriacetica|TrEMBL
MQNRFKESLLDKNTMSVTWELVPGRGAREKSQEEAIAAAEQAAKGGRIHALTLTDNPGGN
PAILADALAKEVLAKGIEPLVHFTCKDKNRNQIESQLYALDRAGIRNLLVMTGDYTVTGY
KGRPKPVFDLDPIHVLGLIGEMNKGLEYQGFKGTIKHQPSDFFAGAAASQFKATEAEQML
QYYKLKKKIEAGAQFIVTQLGYDARKFHEIIQFIRLNGWDIPVVGNIYILPLGTAKVMNK
NRIPGCVVTDKLVADLEREAQAPDKGKEARLLRAAKMYAFMKGMGYNGVHIGGHGMKYED
VEFIIDKGEELSKNWMDFIHEFDYPQPNGFYYYEKDEKTGLNTTTPTNRKGRPLDAPVEF
TYRLSKFMHNLMLEPGTPLWGPMTAVAKAVDGTSMEKKYHKFEHMIKVGLFDCKDCGDCA
LMDVAYVCPMSQCPKNQRNGACGGSFEGWCEVYPGKKKCAWVRAYSRLKNSGKEEQLSKE
IIPPANWDFHQTSSWLNFYLGRDHTAKKFGIEPYVKKK
>A0A7X8JNW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MNVADKLKQATSPLFTFELLPPLKGKGIDAIYKAIDPLLAFNPSYINMTYHSAEVVYKTL
ADGKIEKRTVKKRPGSVALAAAIKYKYNIEVVPHVICSGFNQEETENILIDFHFLDIHNL
LVLRGDPPKGMRVFQPKEDGHEHTLGLMSQINNMNNGRYLDENLKNPEKTTFSMGVAGYP
EKHMEAPNMVSDMKYLKQKVENGAEYIVSQMFFDTQKYIDFVHQCRKEGILVPIVPGIKP
IASMNDIKVLPQIFNIDLPEELVVELKKCTTNDEARQVGIEWCIKQSKELIAFGVPSLHY
YTLGESDNIQKICKAVF
>A0A5N5FB51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrus ussuriensis x Pyrus communis|TrEMBL
MSHSDTIAADGLASPEAYQSDLAYSKRKIPTKVTAALEPIEDNGEVVRLYGIHLGTEMCK
KILAHGIMTLHLYTLNMEKSALAILTVFFSYLSFSVWLDFRCT
>A0A1E7H9F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium C00003106|TrEMBL
MSLKEALDAGKFLITAEIGPGKGTDTGALLEDASAVKDCVDAINVTDMQSSVMRLASMPV
CHLLKDMGIDPVLQVTCRDRNRLALQADLLGAWVLGIRNVLALTGDHPTLGDHPEAKPVF
DLDSVSLLDLIGKLGSGVDMAGHELKGTPNFLSGAVVNPGADTEAALDLQIMKMEKKIAA
GARFFQTQAVYDLDLFEKFMKRVEGFNVPILGGVILLKSAGMARYMNKNVAGVCVPDSLI
KEMTKTKEKVKTSIEIAANLVRGLKDLCHGVHIMALGWEKRVPQVFREAGL
>A0A4P6UGC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hylemonella gracilis|TrEMBL
MSEQPTPQSLPLSIEFFPPKTPEGVEKLRVVRQQLKALKPEFCSVTYGAGGSTQEGTFAA
VREILAEGMDAASHISCIGATQATMRENLAALKAMGVKRLVTLRGDLPSGYGAGGEFHYA
SDLVAFIRDETGEHFHVEVAAYPEVHPQARSPEADLQAFAAKVKAGADSAITQYFYNADA
YFRFVEDADALGVTVPIVPGIMPITSSTQLMRFSDACGAEIPRWVRLRLQGYGDDTASIK
AFGLDVVTALCEQLRAGGAPALHFYSMNQSAATLEICRRLAIV
>Q9S2V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTNFVD
KCRAGADYAITQMFFQPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A2S6TAB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha5_Bin3|TrEMBL
MEYQSLFHKKLLDGNFVYTAETTPPDSADQEVILTKTKPLKYIADAVNLTDSPGAKVHMS
ALTAAIILAQNDIEPILQLTVRDRNRLALQGDLVGASALGVHNILCLSGDDPKIGDQPET
IAVNDIDSLTLVATADLMRRKGKFPSGRLIEPPPKFCIGGAEVPTEGKPNTEKILNKIKT
GINFFQTQYVFDKKILKEYMKVLDDVGILEKTFFIIGLGPFTSAKSAKWMNNNLFGVNVP
DKIIKRLEQSKDEKEESKKICLELIHHFKEINGVMGVHLMGHNKEEIIAEIIQESRKNKN
>A0A2W0CE42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus illinoisensis|TrEMBL
MLQSWLDSLKEFNGITIMLLLIVAASLLQGWSRGASRSAGRLFGFLMDGIMAVIGILLSI
GLTLWLAPYVQQWLSAHASAMPNRDLNRWEQMYYTLVTAIADFPLMRFAVLFVLSYGFIR
LILGLFSSLFFRRRYHSAEQESTPKGIISRFMGAIIGAVIGSARGMIVIAVLFMIVSLYP
GSMFSRYVEASPIYMQGAKSVIEPLSGNLIKDKLPVFTQAVQKELGGILQRKYEVIDHNI
PADIESAASEIVKGQNTEEAKARALYDWVGSRIQYDYGKVDDYEQKGIWHEQTPQNTFDT
RKGVCIDYARLYAVMARSQGLDVKVVTGLGYNGQGGYGPHAWNEIYLSDSQSWIPLDPTW
AVSGDWFNPPNFADTHLKDQTA
>A0A1I4K555|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rugamonas rubra|TrEMBL
METPNFSIEFFPPKTAEGAEKLRATRAQLSLLHPKYFSVTFGAGGSTQRGTLDTVVEILA
AGEQAAPHLSCVGGTRESIRAILAEFKSHNIRRIVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQARSPQDDLLAFERKVKAGADAAITQYFYNADAYFQYVE
QARKLGIAVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTALCQRLLAGGAPGLHFYSMNQAAATTALWQRLV
>A0A5C4PZ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurellaceae bacterium Phil31|TrEMBL
MSYAKEIDHLNHSLANLNGEINVSFEFFPAKNEKMETILWDSIHRLAPLKPKFVSVTYGA
NSGERDRTHGIVKRIQQDTGLIAAPHLTGIDATPDQLRVIAQDYWDSGIRNIVALRGDEP
PGYAKQPFYASDLVKLLKEVADFDISVAAYPEVHPEAKSAQSDLLHLKEKVAAGANRAIT
QFFFDVDSYLRFRDRCVAVGIDVEIVPGILPVTNFKQLQKMATLTNVKVPSWMPKMYQGL
EDDQTTRNLVAASIAIDMVKVLSNEGVKDFHFYTLNRSELTYAICHLLGVRAV
>A0A5N5GYI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrus ussuriensis x Pyrus communis|TrEMBL
MKVIEKIQESLVDEKKVVFSFEFFPPKTEDGVENLLERMDRMVAHGPAFCDITWGAGGST
ADLTLEIANKMQNLICVESMMHLTCTNMPVDKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQIQGGFACALDLVTHIRAKYGDYFGVTVAGYPEAHPDAIAADGLASPEAYQSDLAYL
KRKVDAGADFIVTQLFYDTDVFLKFVNDCRQIGITCPIVPGIMPINNYMGFIRMTGFCKT
KIPAEVTAALEPIKDNEEAVRLYGIHLGTEMCKKILASGIRTLHLYTLNMEKSALAILQN
LGLIEESKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTVGWELYPHGRWGDSGN
PSYGALTDYQFMRPRARDKKLVQEWVVPLKSIEDIYEKFKKFCLGKLKSSPWSELDGLQP
ETGIINELLGKINTKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSKEKL
DALVEKCKALPSLTYMAVNKDGSWVSNTGQTAVNAVTWGVFPAREIIQPTVVDPASFIVW
KDEAFEIWSRGWARLYPEGDSSRKLLEEVQSGYYLVSLVDNDYINGDVFAVFADF
>A0A068TAV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141|TrEMBL
MTADSETFSVSFEFFPPKSDEMEGQLWDTVDELALWDPRFVSVTYGAGGSTKAPTINTVR
RLVGETSLATAAHLTCVDATHEETHSVVSEYRAAGIRHIVALRGDPASGVGTEYRPHPEG
YANAADLVRGLTELGGFDISVSAYPEKHPESTDLAADIEMLKRKADVGAARALTQFFFDN
DVFERYLEKVRAAGISIPIVPGIMPIQNLTQLKRFAGRCGSSVPSFLDARFEGLDDKPED
RAKVAADIAAEQIEDLIRRGLGDFHIYTMNRAPLVSAVLHRLGRRQIRTPRIAAA
>A0A6M1UNR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium SGD-2|TrEMBL
MSSYRFSRRPDTGARLRVSFEFFPPKTEEMEARLWETVVRLAPLKPEFVSVTYGAGGSTR
ERTLHTVRRILTETGLMPAAHLTCVDATREQVDAVIREFADMGVKRFVALRGDSPAGVGQ
PYRPHPDGYTNAAELVAALKRHGDFDITVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPIHNFRQITNFASRCGAHIPAWLAERFE
GLENDPETHQLVAAAVAAEQVLDLVERGVRDFHIYTLNRAGLPLAVCQMIGIRPTPEAVA
EESAAA
>A0A7V8TDR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium sp. CFBP8739|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWQSGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTAMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A0F8F427|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. 2.H.T.1A.6|TrEMBL
MLFNFREKLNSRKFLVTVEVSPPKGTMFSAPLEDACQLKGVADALNVTDNQCSIMHMSSL
AFSKLLLDQGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDHPACGDHPGSKP
VYDLDSVQLIELVRKLDSGIDFAGKRLDGGTSFCAGAVSGIDPENTLQLIKLEKKVRCGA
DFIQTQAVYDVGMFEEFMEAVNHLEVPVIAGLIPLKSLSMAEYMNKNISGIHVPEEIRLR
MKDASSPIEEGLSIASDTIKELTKLSRGVHIMPIGSHKNTPRLLSMAGISGK
>A0A6M7WPH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium loti R88b|TrEMBL
MIGHQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDDITETQVDMVK
TAH
>A0A268K885|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. 7884-1|TrEMBL
MSLLEKLEKQILIADGAMGTLLYSFGKDSCLEELNLSHPEKIQEIHKAYIDAGADVIQTN
TYAANYLKLQRYGLEDSVKAINSAAVQNAKLAAQQNAYVLGTVGGNRGIKPSALSIEELK
RSFREQLYCLLLEEVDGILLETFYDLEELETVLTIARKETKLPIIAQVSLQELGILQDQT
PINEAFTRLESIGADVIGLNCRLGPHHMLKTLEQIELPKHAYLSAYPNASLPAYTDGIFH
YEGDADYFKKSAQSFRQEGVRLLGGCCGTTPAHIQAFASELKNSVPITEKVVKLKTKKII
IEQSAAKRDYQPLEEIVKERPSVIVELDTPRKLDTSKFFEGAKALKEAGIDAITMADNSL
AQVRISNESLGYLVKQELRMRPLIHIACRDRNIIGLQSHLMGLHTLGMHDVLAITGDPAR
VGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTAFSIAGAFNPNVRSVEKAVK
RLEKKIEYGADYFISQPVFSEEKLIEVYEHTKHLNAPIYIGLMPLTGSRNAEFLHNEVPG
IKISQPIRERMAALNDQPHQAAREGIEITKSLIDTALDLFNGIYLITPFLRYELTTELAI
YAKQRASQVRGNNYVESSIQ
>A0A1V2ZF25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. VKM Ac-2630|TrEMBL
MPTNRSETPPDPHCPDRVPFSFEIYPPRSAAAASALTATVDRLAEAEPSFISVTYGAGGS
SRSASLEILRYLRDHTSVEALAHLTCVGSTALEAGRLVHEFLEAGVTRFLALRGDPPTGT
AEGERFLGELGSAAELVQLIHRVQAERQPYGATAVPGSTALRVDPAARPRAQVAVAAFPN
GHPRSRSRSQDIDALLAKEAAGASFAITQLFFHASDYLSFVDRARAAGLRMPIIPGVMPV
TSPGRLRRMLELSGEDLPAELAIALDVEFDEDARIRIGVEHAAGLVRTLVDAGVPAVHLY
AFNRHEAVLAVLAESGLLTAAAPTPTTERAS
>A0A101PYX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces antibioticus|TrEMBL
MGAAGLRALLESVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLVGRLAGH
GYRVVPHVPARLLRDDTHLKDVVDRLAEAGIADVFVPAGDADPPAGGYDGALPVLRRLSE
LGSPFARVGVTGYPESHPLIHDDVTVQAMWDKREHATYIVSNLCFDPRVLGEWLVRIRAR
NITLPVHVGVAGPVQRAKLLAMATKIGVGESTRFLTKHPSWFVRFATPGGYAPERLLSRA
EAALTAPSAGVAGLHLFTFNQIAETERWRRALLDRLGA
>A0A2L0S306|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas orientalis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVNVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHVEVAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFY
FVERVLAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A561T0V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia hierapolitana|TrEMBL
MMSTEINEPAINEPPTRSEPILLGKRDALVRALRNASYEILPFKKTEASVLEHVPLDVAL
TVTTTEAKGLGPTIDLAVRLSRHGYTASPHLAARLVRDDAHLTDIVAQLREAGVQSVFVI
GGDAAEPAGTFPDALSLLQRLDEIGHPFSTVGIGGYPEGHGHIPADLIEKALEQKAPHAT
QVITQLCFDADTTVNWARTIRARGVALPVRVGIPGAVTRQKLVRITAGIGLGQSARFLKK
QQNLFWRFFLPGGYSPTRLVRRLTPSIGAPDNNLAGFHVFTFNELEKTQTWRQEWLARLD
AS
>A0A435U165|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.006.01.1.1|TrEMBL
MNDMRQELIQTRGSAAFAFDAEVSIELAPAQARTFAPQADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSERDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSTIQTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARIVSQF
AFDGDMIAAWASTLHAAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRSPAEILQTMAASYPAPTGPLHLHFFPFGGWEKTLAWFSDYREACWPQVNER
>A0A1Z9AL27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED95|TrEMBL
MSEACKTPISFEFSAPKTEAAFSSLRRAYSRLSRFQHEFISVTYGAGGSTRDGTKHAVTA
LSSEGFTVAPHLSFGGDDEATIAGLLEDYQAAGIKQLVALRGDRQSGQGSAKMVHAAELV
EFIRARTDDWFTIHVAAYPEIHPESISVATEIEFFKQKVDAGADCAITQYFFNVDAYQQF
LAECHKAGITTPIVPGIMPITNLAGLQRFSSICGADLPRWLTKRLETLDGDDVAVKDFGC
EVVTRLCERLIEAGAPGLHFYTLNQSKPSARILENLGY
>A0A4R3VJL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Samsonia erythrinae|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHGIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWQSGIRHIVALRGD
LPQGGGKVDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATLTNVRVPNWMTTMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPEVSR
>A0A0L8NKN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces antibioticus|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPKLSNAHV
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A520CWX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKITDHIKNANGKALFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADSSFVPTKGGHCYATDLIEHIKNHNNGKFLHEDIETFKSDFCIGVAGYP
EKHFEAPNLNADFKYLKKKVDMGAEFIVTQMFFDNQKYFDFVNKCRENGINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPDDLTDALSHAKSNAEAKEIGTAAMIKQCKELIEFGAPVLHF
YTMGKPAQTKEIARAIF
>A0A5M6CPF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium baculatum|TrEMBL
MKVTEHIQNADGKALFSFEILPPLKGQNIQCIFDTIDPLMEFNPPFIDVTYHREEYTYKD
AGNGLLEKKIVKKRPGTVGICAAIQNKYKVDAVPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKAEKNGHRYASELVTQISELNNGIYLDDELENSHTTNFCIGVGAY
PEKHMEAPNFDSDLQFLKQKIDKGADYIVTQMFFDNAKFFDFVDKCRKAGIEVPIIPGLK
PLTSKGQLNMIPHRFKVDLPDALVIEILKAKDNDAVKQIGIEWCIQQSKEIIAAGIPIVH
YYSMGKSDTVKRVAKEVF
>A0A519UXJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
IDAVPHLICGGFTKEETENALIDLQFLGIDNVLALRGDARVADSSFIPTKGGHCYATDLI
QHIKNHNDGKFLHEDVETFKSDFCIGVAGYPEKHFEAPNLNADFKYLKKKVDMGAEFIVT
QMFFDNQKYFDFVKKCRENDINVPIIPGLKPISTLSQLNVLPKIFHIDLPDNLADALSHA
KSNAEAKEIGTEAMIKQCKELIEFGAPVLHFYTMGRPEQTKQIAKAIF
>A0A1F2ZJG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium RIFCSPLOWO2_01_FULL_40_26|TrEMBL
MKTYTNKLEEVVLNTRELSVSFEFFPPKTDEMEEQLWKAISKLKSLKPNFVSVTYGAGGS
TRERTHHTIKRIIDETDLKPASHLTCIAASKEEINEILRNYWKIGVRHIVALRGDMPASS
PNYQLRKDGYQYASELVEGIKKIADFEISVAGYPEKHPEAKNIDEDIDYLKRKVDAGASR
IITQFFFDADVYFSFVEKCRKRGINVPIVPGILPVTNVKQTKHFAKMCGAKIPKWMDQIF
ENLDEKQETRHLIAGIVATELCRILHNGGVNDFHFYTLNRAELTSAICHVLGVR
>A0A519WS66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKIIDHINNAKGNTLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKDETENALIDMQFLGIDN
VLVLRGDARKSDSAFIPTPDGHAFASDLLSQVSDMNKGKYLHDDMGTSERTDFCIGVAGY
PEKHFESPNLDTDFRYLKMKVDMGAEFIVTQMFFDNSKYKEFVDKCRANGINVPIIPGLK
PITNSKQLVSLPKVFHLDIPLALSEAVQACSNEKDVKAVGIEWMINQCKELKAMGAPVLH
FYTMGNPEPTKKIVQGVF
>A0A6N7I9R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangiales bacterium|TrEMBL
MSEFVTELGQRVLVFDGAMGTMLHAAGNSLDRALPELNLSNGELVSTVHESYINAGVDII
QTNTFGANRLRLASHGCAESVRDINLAGVRIAREAQETAERPVFVAGSISPAVAASQRQL
IGPDERTEAIREQVEALVEGGVDLLVFETFGHLDELVEAVRTAGEVGDVPIIAQATFTAD
GYTPGGESPHDVASTLAELPIVALGTNCTLGPQGMLAVVEKLHRYTGLPVSTQPNAGLPR
RVQGRRFEYNIDGDYFARYARRYVEAGASVIGGCCGTTPTHVRAAVAEIAGLRWRRPRRA
ESSAAAAAAPTPTLAPRPTTDEVRGLAEQLAERRFVTAVEVAPSPGGAGDEAADVAAGLR
DHGIGLFLVAARESARAQLSSISLALHLQQRLGVETIATATTWDKTIMTLQADLLGAHAL
GLRTVVCETGNPPLRGDYPNADGIWEVDSVGLIELLAGLNQGRDWSGLTLAAKTSFHIGA
RFKPSADDVDAEIAGTRAKVRAGAQFLVSRPVYETSGLRRIADALSDENVPMLLTISPLR
SFEEAEYLAHEVPDVTIPEATLRAMERAGANGARTGLELATELLEQARPLVQGVVLGIPD
DDAATLDYLRAAI
>A0A6N4WRY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentimonas sp. CC11|TrEMBL
MKSLSIKQRLEINDPLFSVEFFPPKSDDAAQQLLSTAERLQTYNPDFVSITYGAGGSTRS
RTLNYARKLHEDYGYAVMPHLTCVGHSRDELKQTIAEFKAAGLKQIMALRGDPPKGETDF
TPHPDGLSYANELVQLIREVYPECDLGVAGYPEKHPEAPSPELDLLNLKRKVDAGATFIT
TQLFFDNEAYFTFVENCRRAGITVPIMPGLMSVASHKQALRFCDMCGTSIPAALNEQLIA
AGDDKAAVEAVGIEWSYQQARELLEKGAPGIHLYILNRAGPAITLMEKLQSAGFYR
>A0A6F8XPF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytohabitans flavus|TrEMBL
MSVRDELAGMLSRRVLVCDGAMGTVLHAVGNSLDQSLVELNLSNPALVRSVHDSYVEAGA
DIVQTNTFGASRLRLAGYGYADAAAEINRAGVAIARAAAEAAGHRVFVAGSVSPAVTVRQ
RAKATPEERRSALRDQIEALAQAGVDLVVLETFGYLDELVEAIDVAGEVSDLPLIAQSTF
ATDGRTLSGHAPAEVVSAVVARAGSNLFALGVNCTLGPQGSLAVLVQLAERTSVPLSVQP
NAGLPRRVAPDRFEYEVDSDYFARYARKMVAAGAAIVGGCCGTTPEHIRAVVDSVSTVAS
EHSRRATVRPPAERAAPARPASGLLGDAGFVLGGLVGLTAADATDPAGQLAGVLRRAALA
REAGVDLVAVRSEPGVRLPTNPVSAGAAVQDQLGLRAVAGVSTAGKSIMMLQASLLGAHA
RGVTRVICETGTPTLAGDYPNADGRWDVDSVGLAELLAGLNAGADHNGLRLPSRTQFEIG
AWVNPGARDFAAELRRTRAKLDAGVHFLVTRPIFEHIALTRMLEVVAGRVPVLVSLRALA
SFQEAEYLRHEVPDVVLPDSALTALARAGAAQRRVGVELAVDLAQRVAGLAGGLLVGVDD
DPSALVEVQRAVKSLKEGTSAHDQPGPRLAALSGPARTSPTAGRRPSSPRRARARRTPAR
PARRRRPRWHRRSRSARARSPAPGPAPTATSTAAA
>A0A1V4CC03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp. H7|TrEMBL
MGLPLSFEFFPPKTPEGAEKLRVVRQKLYALKPEFCSVTYGAGGSTQKGTFDTVQAILAE
GVDAASHFSCIGATKAGVREQLATLKAMGVRRLVALRGDLPSGYGLGGEFQHASDLVTFI
REETGRDFHIEVAAYPEIHPQAKSPEADLQAYVTKVKAGADSAITQYFYSADAYFRFVDE
ARRHGADVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQAFGDDTESIKAFGLDVV
TDLCDRLRSAGAPALHFYTMNQSVATLEIVRRLAGQQPHH
>A0A3D4NXY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MSDKILHVELQTPKRSSEDIEKDLATFEDKYRKVVAAGWIVCITDNPMGLLSYGAMETIE
LLGLPVHPEQLMVHLNTFHPKKELDGTLDAFRAAGGRHLLVVSGDGSQRLHRLEPAEVGI
DGTTVTSVELLRYIDREYAGRFACGVAFNPYEPQDAELAKMKRKVDAGASFIITQPIIGR
DDRLDALLAFGLPVTLDAWMSKKLHLLSECVGHEIPEGTPYDPMENLKELRQNYPDYGLY
LAILGFKTQYPLLQGIWD
>A0A523ZXZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MKTKSNLERVLEAEQFAVTGELGPPQSADPEVIRRKAKILKGNVDAFNVTDGQTAVVRMA
SWAACLIGKEEGLDPIVQMTCRDRNRIALQMDVLGIAALGINNMLCLTGDHQKFGNHPMA
KGVYDVDSIQLVKMVKDMRDEKKFQCGDEMAVEPRLFIGAAANPFADPF
>A0A246FM38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter amundsenii|TrEMBL
MKVTEHLARAEGKTLFSFEVLPPKKGENIETLFSNIEPLLEFKPPFIDVTYHREEYVYRQ
HANGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFVAEPDGHSYACDLIGQVSDLNKGAYLDEEQDDTWATDFCIGTAGY
PEKHFESPNYAADLRYLKHKVDRGAQYIVTQMFFDNEQFFRFERSCREAGILVPIIPGLK
PLTTKSQLTMLPSAFYLNLPEELADAVHLAPDNAAARQIGLEWCINQSRELMAHGVPCLH
YYSMGKSETIRQVAAALF
>A0A151QII5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnobacter sp. CACIAM 66H1|TrEMBL
MINISFEFFPAKTDEGAEKLRATREKLSERKPEFFSVTFGAGGTTQDGTLSTVLEIKAAG
EEAAPHLSCVGSSREKVAALLKQYKEHGINRIVALRGDLPSGMLETGSFRYASELVEFIR
QETGDHFFIEVAAYPETHPQAKSPAADVDAFVHKVNCGANSAITQYFFNLDAFLYFRDQV
QNRISIPLIPGIMPVTNFSQLARFSDACGAEIPRWMRNRLQHFGDDRESIRAFGLEVVSN
LCEQLIREGAPGLHFYTMNNAQPTLAILDQIGY
>G2XE28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)|TrEMBL
MDKITDKIAALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
AFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPPRKAE
YQDAVDEESDDDEDFVWATDLVKYIRKNHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVEKTQAGADFIMTQLFFDIDAYDHFEQVLREHPSGAFKTIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDALMARLDAVKGDDEKVKEVGVDIVSELVDQIRAVKSKRTTGPQGFHFYTL
NLEKAVSFILERTNLIPDKEQEDEEAVIDDATTPPVVPTVQINGLHPGSHHRPGRRQSSI
GSDPHNRVIVSSASNHAYETNPEGAGLPAEPINTRANTLAISEGEGVLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVTQAVRLWGHPKSSEDISTLFIKHIRGELSAIPWSEE
GLSPETNIIQEQLIELNTRGWWTVASQPAVNGVPSRDATFGWGPSHGFVFQKAFVELFLP
AADWKVLSERLTGPEVEGTVCFYACNGNGDFATSDDSGGLVRTAVPASTNAVTWGVFPGK
EIITPTIIEEVSFRAWSEEAFKIWGEWSRVYGRGHESEKFLKSVKDEYWLVNIIHHDFVE
TNALWDLLRG
>A0A3A8YD94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium 1xD8-6|TrEMBL
MKIANLYRKGKTVLSFEIFPPKRDSELKNIDATLEILCELKPDFISVTFGAGGSSNCNRT
IELAKKIKYTYQVEPVVHLTCLSYDKAEIDNFSALLKSEGIENILALRGDRNPDIPEKED
FRHASDLISYLKQTEEFCIAGACYPECHPESLDRVSEFKFLKKKVDAGAEVLLSQLFFDN
EIFYRFREDCRIAGIEVPVIPGIMPVINAAQIKRMVTLCGASFPERFQKIIHKFEGCRDA
LFDAGMSYALSQIIDLLANDIQGIHLYTMNNPAVARKICEGIKNIVVPN
>A0A8J6UHG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aestuariibaculum sediminum|TrEMBL
MKVTDHIKKANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVD
KGNGLLDKRITRMRPGTVGICASIMHKYNVDAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VVALRGDSRKDESYFVPTQGGHAFASELVQQISSLNKGKYLHDDIEVEHNYDFCVGVAGY
PEKHMEAPSLNTDLKRLKEKVDAGADYVVTQMFFDNKKYFDFVEKARAIGITVPIIPGIK
PIAVKRHLQILPQVFKIDLPEDLIDAVEGCKDNKAVRQVGIEFAIQQSKELKDAGVPFLH
YYSMGKSDNIKAIASELF
>A0A484TYN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|plant metagenome|TrEMBL
MGVAVVRKPALHACYSMEVSAKDIPALTEVAPRLPPASTIAIPYLAGEGNEARLAAARAV
RELGFEPMPHISARRVASLAELHAFVERAAAEAGVERCFVIAGDPSTPKGPFPDSFSLID
TGVFERAGIKAIGVGGHPEGHPVMSVADRWDVLERKCRSIERRGMAPSIVTQFVFDADVV
LTWLEALRARGIAHPVRVGVPGPAGVAVLARYAAMCGVGACASMLSKYGISLGKLLGTAG
PDRFVDRLAAGLTQAHGTVSLHFFPFGGIAQSVRWIEQYRAR
>W2D1F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella sp. oral taxon BU063 isolate Cell 8/11|TrEMBL
MERVIDLINKSRGTAFSFEILPPLKGNSIQSVYRVIDKLRDFDPKYINITSHHSEAIEVR
GTDGMVRTVNLRKRPGSVAIASAIQNRYGIAAVPHLVCKGFTKDETEYGLIDLNFLGVNN
LLLLRGDVKRLHEPDNAELYHDHATDLQLQVNNFNRGIALDGSPITDIETPFSYGMACYP
EMHEDALSMDDDVRYAKLKVEQGAEYLVTQMFFDNAKYYAFVDRMRAEGVTVPIIPGIKP
IVLRDQLEVIPRIFHCTFPPEFAAALGRCRTDEEAKEVGVEWCTAQCRDLVAHGVPSIHF
YTLMASDSIRRVAKEIY
>A0A662LRV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MTTKTPSKLEKILAAGHLAVTSECGPPRGSDGEAIAKKAEMIKNHVDAINITDNQTSVTR
LCSLAACIRLKLMGLEAVLQMVVRDRNRIALQSDILGAASFDINNILCLSGDHQVFGDNS
RGQNVFDIDSMQLIQTVRYMRDEGKFLGGDEIKRPPRMFVGAAANPFADPFDIRVPRLAK
KIAAGAEFIQTQCLYNLDKFELWLKQAGDRGLLDKVAVLAGLTPLKSAGMAKYMKNRVPG
MDVPDDVVKRISDVPKEKQADEGIKICIESIQRLKEVEGVKGFHIMAIEWEEKVPEIVEQ
GGLYPRPEVEE
>A0A844LA69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp. VBW004|TrEMBL
MKRISFEFFPPKTEQGKEKLLATQQKLQVKNPEFFSCTFGAGGSTRDNTRDMVNKLREQH
GDTAPHLSCIGQSREEILELVNGYKAAGVTRIVALRGDLPSGMGYAQSEIKYADELVQLI
RQETGDHFTLEVAAYPEMHPQARSFEDDIAHFKRKVDAGANSGLTQYFYNADAYGYYMDA
LHKAGCNAPVYPGIMPILNVANLLRFSSTCGADVPRWLQSKLNDIKDDDAAVKAFGEEVV
TRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGM
>U6F7W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus CIRM-BIA 951|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSEEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNHADIAERIWNATKSVFDAANARTQTTIKHRS
>A0A1H4CEM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bowdeniella nasicola|TrEMBL
MTLTDVYRRSGRTSPVISYELFPPRVPDPHSAPWAGIVKLLNSRPEYVSVTFGASGSSQE
LSRTVLRQVLQRTGRPGLAHLTCVGRNRQQLDRLISELIAEGARDFLALRGDPTSWPDPL
GVSPRGIIARPPGDERSLADHSGPYPPVLLGVRGRRGRHRQPRRRCHLDRGVSLEDGYLA
GGRRPRFFAPAGIWDIHSPRIPTLEEEVALLRAATAALDPRQLWVNPDCGLKTRAYPETI
ATLRNLVAAAAEVRDEVSS
>A0A1K2H3S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinimonas taiwanensis DSM 18899|TrEMBL
MSPSPTFSFEFFPPKTVEGTEKLRNTRRQLAQFKPEFFSVTFGAGGTTQDGTLATVLEIK
SEGFQAAPHLSCIGATRANVAQLLQTYRDNGIRRIVALRGDIPSGMVEFGEFRYANELVE
FIRAEHGDWFHIEVAAYPEYHPQARSAHDDIANFVRKAQAGADSAMTQYFFNPDAYFAFV
DEVRARGVEIPIVPGIMPINNFTQLARFSDACGAEIPRWLRLKLQSYGDDSASIKALGLD
VITDLCRKLLDGGAPGLHFYTLNAAGNVSTIWQRLGLDAR
>A0A5E8KWR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPGYVSCTFGAGGSTLNYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
AALCERLMAGGAPALHFYTLNLAKPTTQVLQLLGR
>V2UI31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter tjernbergiae DSM 14971 = CIP 107465|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRGVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDYFHIEVAAYPEMHPQAESFDTDIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>C9P1W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio metschnikovii CIP 69.14|TrEMBL
MGYTHASHIDALNQSIAEVSDINVSFEFFPPSTPQMEETLWSSVHRLKELKPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDASREALITIADDYWHNGIESIVALRGDI
PPGGGKPEMYAADLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDIESYLRFRDRCVAAGIDAEIIPGILPVSNFKQAARFAAQNHVKVPQWMAKQFAG
LDDDPVTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPIAVT
>A0A4T0UQ66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. GY 10127|TrEMBL
MTIGRGRSLTDLVREGRRSFSFEFFPPKDEAGEAQLWETVRELEAYEPSFVSVTYGAGGS
SRDRTLRITRRIAEETSLLPMAHLTCVGHTREELGQILDDYAAAGVHHLMALRGDPEDGP
RAEWTPTPGGLTHAHELVEMAAATGQFRIGVAAFPETHPSSPSLDHDADVLALKARAGAE
FAVTQMFFRAADYVDLVERVRERGVELPVLPGIMPILNLAAIRRQGELIGTEVPADVVAR
IAAHEGDPVSMRAEGIALAAELCAELLDAGAPGLHFYTLNRSRATREIFEKLDVARG
>A0A846VV79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium R_SAG8|TrEMBL
MTSPAVSFEVFPPKSVDASFRLWDTAQALAPLAPRFFSVTYGAGGSTRDLTHDSAHVLRR
TSGLPVAAHLTCVGASKAETLEVADSFAEIGVTDIVALRGDPENGAPTFTPHADGFADSV
ELIEALAKTGKFTLRVGAYPEPHPESHDQAQNVEWLKRKFDAGADEAITQFFFETETFLR
FRDACAAAGITKTITPGIMPVTNWKSARNFATRCGASVPAALDEAYAAAIRDDRHDLLST
ALCTEMCSELVSEGVENLHFYTLNRPELTRAVCRALGVTAQTSLSDVA
>A0A7C1ZVC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon|TrEMBL
MKISVILKETKETRFSLEVFPPKTGVSERIPIQRHLSNIFETVEHLIKYNPIFVSVTYNP
EGKTKTTSIPLAAIIKQKYNVEAVAHLTCISTPREELSKTLDVIDYFDIENILALRGDLP
DSSLPRGELRHASDLVEEITKHEKGFCIGVACYPEGHPECVTEEGERDLEKDLLHFKAKV
DKGADFAITQLFFDNNVFFSFVKKARDIGVKVPIIPGIMPIRSYNMVNIVKRLGNISMPY
SLVKKLEDNRDNKAEIMEIGVEQAIKQCRGLMNKVPCIHFYTMDRWMSVDRILKELS
>A0A5K7YEJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia sp. AM6|TrEMBL
MSASEHPSGISFEFFPPNTEAGREKLKGVRDQLAALEPEFFSVTYGAGGSTRERTFNTVQ
SVSASGICTAPHLSCVGSDRGELREILAQYREQGVKRLVALRGDLPSGMGSRSELRYANE
LVEFVREETGDHFEIAVAAYPECHPQADNYHSDLENFARKMQAGADIAITQYFFNADAYF
HFVERARAAGIQQPIIPGIMPITNYTRLARFSDSCGADIPRWLRRQLESYGDDSESLQAF
GTEVISRMSQRLLDGGAPGLHFYTLNQAEPCLKVLENLGISSR
>A0A444JAE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electrothrix marina|TrEMBL
MNALGLQSRMMEAHLLGIEAVLAVSGDSAAGTDQPGVSGVFDLRSEGLIRMLDSMNRGMN
MAGRPLKQQANFSIGAAFSFRPASPDLQIRRLEKKTALGARYAMTQPLFSADEIEQMMEQ
VRHIDILMFPGIFPLISSRNAEFLHNEVPGIYVPAELRKQLARFDEVADQRKAALEYTAG
LVEKNFFLY
>A0A3S3YJU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MALKNDARGRNIRVSFEFFPPKSEEMEGQLWHTVSQLQDWDPDFVSVTYGAGGTTRAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGVPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRPAAKQKVLAL
PPDLCASEGHAAL
>A0A127A1B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinomonas atrocyanea|TrEMBL
MSPPTFIDVPGAAAPAPIALSYELFPPRSAAASQTLWTTIRELEATDPDYVSVTYGASGS
NHDTALELVDRLQLETTLRPLAHLTCVGGTPEELTAVVNELLDRGVRGILALRGDAPRDG
ALPRGALRYAQDLIELIRRVEGRRCAQFAAGKVAIGVAAYPTRHPESPSEVHDIEVLLAK
QRSGADFAITQVFFHADQYASLVHRARRAGVTIPIIPGIMPFTSLRRVEKLAQLSGVAPD
PALVDRLRSAGDDAAAVRRIGTEASVRLAEAALGAGAPGLHLYTFNEHGAALDVLARLDL
PRPSRPLLAARHRVAAV
>A0A417GRR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. AM29-23AC|TrEMBL
MKISELLKQDKVTLSFEVFPPKTSSSYESVARATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAKMVQKYKENGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCIGGACYPEGHVEAANKTEDILHLKEKVEAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVIAGIMPVTNVNQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQASLSEILG
>A0A399XEQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Brocadia sp|TrEMBL
MKSGSNLEKLLRSGQFAVTAELGPPRGADRSAVEKKAELLKGYGDAFNITDCQTAVVRMS
SIAAGRIVLDAGLEPIIQMTCRDRNRIAIQSDLLGAAALGAKNLLCLTGDHQKFGDHPMA
KGVFDIDSIQLIHMVKTLRDGKKFQGGQELKASEPKFFIGAAENPFADPFKFRAIRLAKK
IAAGADFIQTQIIYNTKKFKEWMKIVTDMGLHEKTFILAGVAPLKSAGMAKHMKHNVPGM
DVSDEVVNRMTVASAAKKGKEEGMKICLEVIEQVREVKGVAGVHIMAVEWEEAVPEIVRQ
GGLYPRPVV
>A0A4R2F7W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella fodinae|TrEMBL
MAFHHAQYASSLNQSLAELNGDINVSFEFFPPATEEMETLLWNSIQRLQPLQPKFVSVTY
GANSGVRDRTHGVIERIQKETSLVAAPHLTLVDASDEDLLQLAKNYWHSGIRNIVALRGD
LPEGSAKPTRFAADLVRLLRSVADFDISVAAYPEVHPDAANAQADLVNLKRKIDAGASRA
ITQFFFDIEAYLRFRDRCVAAGIDVEIVPGILPVTNFKQLKRFAGMTNVNLPGWLHQQFD
GLDEDPSTRSLVGASVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHILGVRPKASP
>A0A154I7I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MALKNDARGRNIRVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTRAPTL
TTVTRFLSQTPLATAAHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGVPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISISVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRRQTKSAGAAA
>X6J5X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L103C565B0|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDEIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
IAH
>A0A523N2K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospina sp|TrEMBL
MKINALLKHNRPAFSFEFFPPKDDAGFALLFETIEQLVSCKPIYVSVTYGAGGSTRTKTL
DLVGRIKNEIGLESMAHLTCVGSDAEEIKDILETLRDRGIENVLALRGDPPKGQEKFEKH
EKGFGYGNELVEFIKRDFDFCVGVAGYPEGHIECPDKAQDLINLKRKVDAGADFIVTQLF
FDNKFYFDFVERAAAIGIQVPIIPGIMPIMNVNQIKRFTKMCGATLPDALLSSLEAVQDN
PDEVRRIGIDHATAQCENLVAEGAPGIHFYTLNRSNATLKILENLNKLVKTTKSL
>A0A228Q068|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. AU6039|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVM
>A0A7K3MSB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTEHIENAQGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYAVDTVPHVLCGGFTKEETEYLLVDCHYLEINN
VMALRGDAMKEEQSFVAKEGGNNYAVDLVKQIHQLNQGKYLHDVMHIDNKADFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFDFVKKARAIGIMVPIIPGIK
PIAVKRHLQILPQIFRIDLPEDLIHAIDQCKSPADIKQVGVEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A7Y8GTB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga aromaticivorans|TrEMBL
MALPVSFEFFPPKTPEGAEKLRAVRQQLYGQKPEFCSVTYGAGGSTQQGTFDTVGAILAE
GVDAASHFSCIGATKASVREQLSTLKAMGVKRLVALRGDLPSGYGIGGEFHYASDLVAFI
RAETGRDFHIEVAAYPEVHPQAKSPESDLQAFATKVRAGADSAITQYFYNSDAYFRFVDE
AHKLGVDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDIASIKAFGLDVV
TDLCDQLRNAGVPALHFYTMNQSVATLEIVKRLELG
>A0A8I0B534|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomicrobiaceae bacterium|TrEMBL
MRIDELLATGRPFLSLEFFPPKDRRLWPGFFDTVRALAPVKPLFCSVTYGAGGSTQHNTL
EIGVRLKQEYGLEPLTHLTCVGASEARLRAFLGPLVENGVENVLALRGDPPRGESQFRPE
SDQFQHASDLVRFIVSEYPGVCIGVAGYPEKHPEARSMEEDLVFLKHKVEAGASFVITQL
FFDNDIYFRFVDRARAIGIDVPIIPGVLPVQNLPALHRMLSFCGASIPKDFLEDLTRAHE
RYGDAGVRGLGLGYAMRQAADLLQRGAPGVHLYTLNKADACLEIGRHVAQYLGLGGER
>A0A854XT96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris|TrEMBL
MKTLDSLRALSPDFISVTCSDNNYENIADTTIKFADYVNNTLNIPAVAHLPAAYLDKTQV
IEILERLREKQIMKVLALRGDISDEATKKDFKYASDLVKFIKDYDSSFEVLGACYPDVHP
ESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYDFQERCAIAEINVPILAGIMPVINR
NQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAGIAYAIDQIVDLVTEDVAGIHLYTM
NNSETARSIHSSISSLFKINT
>A0A5Q6RZI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mumia zhuanghuii|TrEMBL
MSTPRRLSEDIAAPAPSFSFEFFPPKTDAGERALWTAIRQLETLRPTFVSVTYGAGGSTR
DRTVRITERIATETTLRPMGHLTCVGQTRDELRNVLGQYAAAGVRNIMALRGDPVGGPGA
PWTPHPGGLDHGDELVALVSGLGSFCIGAAAYPKGHREAPDLDADADVVVAKARAGAEFV
VTDFFFLAEDYFSLVDRVRARGCDIPVVPGIMPITNLAQIKRMAELSGHPVPASVVSRLE
PWADDADGLRSEGTLVATELCDALLEGGAPGLHFYTLNRSSATRHIYESLAVARV
>A0A8B3SYN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSDMEETLWTSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMSAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAAAA
>A0A7C2M0M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
MALFTPGRRWQPPFLPFKKEKFGKRLLRKIERLTKGPLFGCRMCGNCLLQETAFICPMEC
PKGMRNGPCGGSTPERCYVDETRPCIWYRIYDRSFRMGREEKLLEVLPPLDWDKVGTETW
GDVFRSVRRFGTGKFLRSLVSGDKEKKADAWEGVFRPVRQPGWWQGDSQYHPPAYAEPIS
PLEQQLRSGKFVITAEISPPLGTATGKLTRDIEMVRELVAAVNFTDSASASPRMSSMACC
KVASELGVDPVLQIAARDKTRSGLQSDVVGANVMGVRNVLCITGDHARIGPTPTSNTNIL
DMDAVQMLWILRRMRDEGIYLDGRKMKSPPRLFLGAAASPFASEPRFQALREQKKIHAGA
QFFQTNVIFDPEGLDEWLEALYKRDVLGKVYILAGVTPIRSKRMANYLHHTIPGVRVPEM
ILNRFEQAREDDYEEVGVEIALGIIEKIKSKQGIHGLHLMSVGWEAILPRIIREAALTPQ
P
>A0A5Q6RP80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mumia zhuanghuii|TrEMBL
MSLAQRIAARGSEFLLFALTPPRLTVSTERAQEIADVTQKRLAPLRVDGLVLYDIDDESD
RNPDERPFPFLPTMDPATFRAQHLNDWHAPVVVYRAVSKYQESGLQAWLESQDADQALTV
FVGASSRHKQSATSLVRAQELWAQTRPDVQLGGVAIPERHTRRGEEHLRLIAKQQAGCSF
FVTQVVYDVNAAKDLVSDYRYECAARGLEPVPIVFTFSVCGSVKTLEFLRWLGVDVPRWL
QNDLRHAEDTLQMSYEQSLAAASELIRYCRRMEVPFGINVESVSIRLAEIEASVKLAQQL
DRELRR
>A0A6P6AAB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Durio zibethinus|TrEMBL
MYIGLLSGNSVISATPTPTRFSLKYCQLNFPRSRTSISLPISNPIFKMKVIEKIQSLLED
QGKVVFSFEFFPPKTEDGVDNLFDRMDRMVAHNPSFCDITWGAGGSTADLTLDIANKMQN
IICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQVEGGFACAL
DLVKHIRAKYGDYFGITVAGYPEAHPDAIGSEGVATPEAYQNDLAYLKRKVDAGADLIVT
QLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPDEITAALEPI
KDNEEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLGLIEESKISRFL
PWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSRNPSYGALSDYQFMR
PRARDKKLHQEWATPLKCIDDIQEKFKNYCLGKLRSSPWSELDGLQPETKVIHEQLGRIN
LKGFLTINSQPAVNGECSDSPSVGWGGPGGYVYQKAYLEFFCSMEKLDALVNKCKAFSSV
TYFAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFMVWKDEAFEIWSRSWA
ALYPDGDPSKKFLEEIQSSYYLVSLVDNDYMSGDIFAVFEDL
>A0A498EZE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobellus sp. Atlit-31R|TrEMBL
MSLGAQRGTENGAEYLLSEARFELMPFDSFDDEIEELPDGASVAITTSPQLGIEQTVERS
EQAAAAGYEVVPHIAARYVEDRDQLEEIARRLTEAGITDIFVPGGDKEEPGEFESAYKLL
VALDELPYSFDEVGITGYPEGHDFLSAETLAEAMEKKAPYATYIVTQLCYDPDAIIEWTE
EIRSRGVDLPIEVGIPGVMNYQRLLKISRKVGVGDSVKFLRKTTGIVGFVKQLVGSRGVY
KPDELIDGLAPYVGDDTYKIRGVHIYTFNQTPDLEQWRRGRLQ
>A0A2M9T294|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. WSUCF-018B|TrEMBL
MGLLDELKQRILIADGAMGTLLYSHGVDRCFEELNLSNPDEIIHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGGAYVLGTIGGLRTLNKSVVPLDEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALSRLEALGADVVGLNCRLGPHYMIQSLEEVPLPNRAFLSAYPNASLPDYRDGRLV
YETNAEYFEEAAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTRRSVIVELDPPKQLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIVKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDVSSFDLIRLISQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPVYSEEKIVQIYETTKHLATPIYIGIMPLVSARNAEFLHHEVPGIT
LSDEIRARMAACGSDPVEAAREGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A6G2TIB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8366|TrEMBL
MGTALLDDFSLEMTGKDVPALEEAGGSIPRGTRINVTFLAGEDHATRLAAARAVRRLGFV
PVPHISARRLPSRAALEEFLAGLAEDGTADDVFVVGGDPARPEGPYEDALAVIRSGLLER
HGVRHIGISGYPEGHPAISGPALWSALTDKAAAIGAGPFTGDVITQFGFDAEPVLDWLAA
VRARGVDLPVRIGVPGPAGVRRLVGYATRFGVGTSASVARKYGFSLTNLLGTAGPDRFLH
ALGERYDPARHGVVKVHFYTFGGLRTTAQWVGAFRERAR
>A0A2D7Y4T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maricaulis sp|TrEMBL
MNAVDKTLDRDSGLTVSFEFFPPKTEKMEERLWETVQRLEPIDPAFVSVTYGAGGSTRER
THGTVKRIAQETGLRPAGHLTCVSATKEEVLAVAEDYWQAGVKHIVALRGDPPEGMGARF
EPHPDGFRNSVELVEGLRAHRPELGKCFEVSVSCYPELHPESQGWEAEIAFLKAKQDAGA
DRAITQFFYEPAVYLNFLERARAGGVTMPIVPGIMLQPNFNGLKKIAGLCGASLPAWLHE
LYSGLDDDAETRELVTANVAAELCQKLAAEGVRDFHFYTLNRAGLALSTCHLLGAKPKSA
KAA
>C4JG55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Uncinocarpus reesii (strain UAMH 1704)|TrEMBL
MHIKDKLAHSEAAGRPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFVDITWGAGGRLS
DLTAEMVNVSQSVYGLETCMHLTCTDMPREKVDWALQSAYKAGCTNILALRGDPPREKEA
WAPTEGGFQYAKDLVKYIREKYGNHFDIGVAGYPEGCEDQEDPELLMTHLKEKVDAGGTF
IITQMFYDVDIFLDWVKRCREQGIKVPILPGIMPISTYAAFLRRSNWVKCRVPPSWMEAL
EPCKNDDAAVKQIGKKLVSEMCRKILDSGIRHLHFYTMNLAQSTKMVLEELDLIPSSETP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSIKDLSSIFVRFLEAKLDRLPWSESSITEETDIIKQDLID
LNNRGFLTINSQPAINGASSSHPVYGWGPKNGYVYQKAYLELLIPPEIIDEVITRIQKNA
DLTYYATNKNGELKTNTSDSPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDARSPSRQLIQRVMDEWYLVNIVNNDFHKTHDIFDLFKDLTVKGLDVELTEIVDPAS
QPADAILGQLNGDTTQDIKGNGQSN
>A0A1T4VJX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterovibrio nigricans DSM 22720|TrEMBL
MLLGGVTIPERHLVKGDEHLRVFKKIEAGCSFFVSQGVYDVHASKDFLSDYYYYGKKHGI
PLVPIIFTLTPCGSHKTLQFMKWLGINIPRWLENDLIHSDDILQQSVDHSEQSWRELKAF
ADEKGIPIGCNIESVAVRKVEIDASIALLNRINSI
>A0A0A1YUD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens LMG 5329|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQAHSFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITNMCEDLLNGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1M7SRU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium gondwanense DSM 13020|TrEMBL
MKIPEKLKEGKVISIEIVPPKRGEDVENIYRALDKLMKYNISFVNITRHPVEIEYIEHDN
QIIKVPKVKRPGTIGLTAAIMKRYDVDVVPHIVCIGMNKYEIEDLLIDLSIMGVDNVFVI
RGDVDERFINTKSDYKYAYQLVSQINEMNSGRYLYTQAKPTDFCIGVAGYPEKHYEAPNF
ETDLRFLKQKVGNGADFVITQMVFSAEVYKSFVERCRSEGINVPIIPGVKPLVNKKSLYM
VPKRFFVSIPQSFVEALENARSKEEEYNVGIKFSLKLIEALFESGAPGVHLFTMGRGDEI
CEIMKEIENVL
>A0A258HE07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas subvibrioides|TrEMBL
MAAAVSPLAEARALLLSPLGPVARAGQNANPVRVSFEFFPPKTDKAEETLWQAVRRLEPL
HPEFVSVTYGAGGSTRERTHRTVQRMLTETTLKPAAHLTCVDASRSEVDEVIRDYKAIGV
NHIVALRGDPPGATGIGGAYQPRADGYANATELTQAISRVGGFDVTVGVYPERHPESPSI
DHDIDVLKAKIDAGATRAVSQFFFDIDAFLRFHDRVRAAGVTIPLIPGIMPVSNFAGLVR
MCGSCGASVPDWLAAHFEGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRADL
VYAICRVLGVREQSSPIGGGGPQGGGGGLPHTPESGVNPLRHSASLRATSPNGGGLA
>A0A413QPW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera sp. AM44-1BH|TrEMBL
MKTCDLFSKKTVFSFEVFPPKKEIPVETVYPTLEKLSGLHPDFISVTCGAGGKGGNLTVE
VASKIKSLGCETAAHLPCINLDKEEVLDTLQKLREHGIENILALRGDKTPGIEPKCVFPH
ASDLIAFIRQQTGDEFNVIGACYPEGHPNSKTLAEDVEHLKIKVDAGASELITQLFFDNH
DFYNFLDKSTQAGIRVPIEAGIMPVTNKKQIERMVTLCGATLPLKFQKILTRYGHDNTAL
RDAGIAYAIDQIVDLLANGVDGVHIYTMNNPYVATRIADAIRTLL
>A0A5C7A3I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter frigidicola|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALCA
RGNTDIAPHMSCIGDDKAQIAELLEHYKSLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFHIEVASYPEMHPQARSFESDVDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTVAQPLVAGIMPITNSSNLMRFADSCGADIPRYVRKQLADFGDDSKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLTS
>A0A2D6J0L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidales bacterium|TrEMBL
MTNSLFEEKLQSDEFLVTTEIGPPKGTDNSEMVEHIDLLKDKVDAINITDHQSSVMRFPS
IGGCLLVKEHGGEPILQITCRDRNRLAIQAELLLAYSRGIGNVLCLTGDSIDVGDHKEAK
PVFDLDSVQLLRMIRTMESGTDIGGNELKGAPKFCLGASVHPEADFIEPQLIKFDKKIAA
GAQFFQTQSIFDLDSFRRFIQYAAQFDVKILAGIIVLASARMAQFMNNNVPGIMVPQAII
DELSSVEKGKVLQKGIEIAVRLIKTIKEENLCHGIHIMAVGRERIVPDILEAAELVRVSP
K
>A0A2D6IZM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidales bacterium|TrEMBL
MKIRDLIANERTSLSFEFFPPKAKEGEDHLFGTVRRLEPFTPNFVSVTYGAGGGTLKNTR
HVVKRIKEETSLTPMPHLTCIGQHQEELKAILSDYTAMGVENILALRGDPPEETTGHATK
DRLCYANDLVQLAASLDAFSIGVAVYPEGHCESPNLGIDMVYTKEKIDAGADFAITQMFF
DNRYFYQFMERADRAGIRVPVISGIMPITNIEKVKRFSQMCGATLPAHLVERMEVAASPA
EVRKIGIDFAVKQCEDLWGNGVRYFHFYTMNRSKAVAEILHSLDLGQGSNRRFTTAGESI
>A0A553GTZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mangiferae|TrEMBL
MTSSRSSISFEFFPTKTEAGHEKLLENAHRLALRQPDFFSCTYGAGGSTRDRTLETVLQL
DREVKVQTAPHLSCVGDTKAELRTLLGRYREAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRQETGEHFHIEVAAYPETHPQARNFDVDLANFVRKARAGASSAITQYFFNADSYF
YFVERVRAQGVEIPIIPGIMPITNYSKLARFSDACGTEIPRWIRKQLESYGDDTASILAF
GEQVMTQLCERLLAGGAPGLHFYTLNQAEPSLALCDNLGLSR
>A0A0P7CB06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. R43|TrEMBL
MRESTTSNEQPARGFELICEIEPPTRPDLTHARHQIGVLSPVADAFLIPDNHIGRATVSS
IAVAHEVQTMGGRSIACVNSRDRNLLGLRRDLLTAAAYGVEEFLFVRGDKPSAGNRTGDL
TVRAMIDEARAAGEDPVFADMPAFRVGAAAGLRPLPAWKQAADFLFVQVSYSVDALLRWR
DAHPVELPVYAGVMVLASAGMARRLAATIPDIDIPDDLVQAVERDRAAGVEAACDQVLRL
RDSGAFAGAHLVPVSRYRQVAARLEDLL
>A0A519N8Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
DPLMEFKPPFIDVTSLREDYIFKEHQNGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHL
LCGGFTKGETENALIDLQFLGIENVLVLRGDARRGDASFVPTPGGHCYATDLLQQVVDMN
NGKYLKQKIDMGAKFIVTQMFFDNQKYFDFVNGCRANGIDVPIIPGLKPITNSKQLVSLS
KTFFIDMPEDLCDAVHACKDEKAVREAGIEWMINQCKELVAFGAPVLHFYTMSNAGPTKR
IAEAIF
>A0A7U2IBR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)|TrEMBL
MHISQKLAQAKAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQTVYGLETCMHLTCTDMEKTKLDEALRDAYQSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVKYIKEKYGNHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGATF
IVTQMFYDTDIFIDWVNKVRAKGVDAVIIPGIMPIHTHASFLRRAQWTRCNIPQHWTDAL
EPIKNDDVEVREVGKGLVADMCRRLIEAGITHLHFYTMNLAQATRMVLEELDLLPDPGSP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPLSIKDLSDLFVRYMEGKLESLPWSEQPITGEATSIRNDLID
LNRRGFLTINSQPAVNGAKSSDPTFGWGPRNGYVYQKAYLEVLVSPEYIAEIITRIERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHGGASPSRFVIQDVVDTWYLLNIVHNDFHATRGIFPIFDGLQVKDIDKKLHSVNIDL
PGAEETNGANGTNGANGKNSETKEAYGEEKQNPGLLAVAKAAAIEVTNGIKGLGVSN
>A0A7C5GRS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MAQTRLKEALDRGDFVITAEICPPRGTDTTQFIEKARLLKERIVAANVTDNQRAVMRLSS
LASSVLLLKEGVEPVFQMTCRDRNRLAIQSDVMGAWVLGIKNILLLTGDHVSFGDHRDAK
AVYDLDSVQLVQTVEGLNRGVNLKGRELRGGTDFYIGAVVSPEAEPFEPEWIKFEKKVDA
GARFFQTQAIFDMERFKRFFDDALKLGVKVLAGILLLKSAKMAHYLNANVPGIKVPQSII
EELEASGDELQKGIEIAARQIRELRRFCHGAHIMAIGKEEKVVDIIELS
>A0A6G2K152|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MAGSPRRRRLAGESPEHRAARAAVIEASSFEVIPLRSLDAAVEALPCGSRVSVTASPAKG
LAATQEITEQLIAAGHAAVPHISARLVRDRTHTRALAAWLRSTQTEEIFLVGGDVAEPGR
YPDALSFLGDLLEAGPGLRRVGVTAYPDGHPLIDPATLDSALTDKQAMLAEAGLAGYSST
QMCFDPERIAGWLRRQRRQGMDLPVHLGIAGVVDRAKLLSIGLRLGIGQSLRYLRKNRRA
VTRLLTAPHYDPNDLLVPLSPHLVELDIRALHIFTFNQVAATAAWREQNLR
>A0A7X7YA57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTESVLEKVLASGQMAVTSECGPPRGSVPDKIIEKANLLKGYVDAINVTDNQTAMVRMS
SWSSCIFIKQMGLNPILQMVTRDRNRLAMQSDILGAYAHGINTMLCLSGDHPKFGDHPMA
AGVYDLDSIQLVRMVKDMRDEGKFQGGADIVNPPKMFIGAAANPFADPFELRVARLAKKV
KAGVDFIQTQCIYNVDKFEKWMEGVRERGLHKQVYILAGITPMKSVGMAKYMKNKVPGMD
VPDEVVKRMSSVPKEKQAEEGIKIALETIERLKGVEGVNGFHIMAIEWEEKVPEMVERAG
LLPRPQV
>A0A7V5M7V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTSGSRLEKILAKGIFAVTSECGPPRGADPEVIRKKGMLIKDSVDAINVTDNQTSVVRMS
SLSSCVILKQMGADPVLQMVTRDRNRIAIQSDILGAAALGLNNILCLSGDHQKFGDHAKA
KNVYDLDSIHLIQTVKQMRDEGKFLGGDEIKGVPRLFIGAAANPFADPFEFRVIRLAKKV
AAGAQFIQTQCIYNLDRFKRWMELVRARGLHEKVYLLGGVTPLKSLGMANYMKKMVPGMD
VPDEIITRLKGVPKEKQAEEGIKICVETIQQLKEIEGVKGVHIMAIEWEEMVPRIVKEAG
LLPRPQVE
>A0A7W4KM07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. 0.2392|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6G6GVT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus delbrueckii subsp. bulgaricus|TrEMBL
MSLTALFKNKTVFSLEVVPPKKDSPKEAILPTLQQLQSINPDFISVTSGAGGSDHYTGTV
QIADLIQNQLNIPAVAHVPGLYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDF
NHANDLVAFVHQNRPDFSIASACYPNCHPEATGFVDDIAHLRTKVDAGADYLISQLFFDN
QAFYDFQEKAEIAGIHVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILNRYQNSKEA
MREAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHR
S
>A0A356GQK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MQTILDRMRETPLIFDGAMGTMLYERGVFLNACFDELCLSNPKIVRQIHQEYLEAGAEVI
ETNTFGANRIALRGYGLGDRVEAINREGVRIAREVAGDSAYVAAAVGPCIRTGQILLEGH
ADEVEASFAEQVGALAAEGVDLVVLETFTGLSELLLAARAARRFGLTVLASFMVNDRGET
ALGTLAESMAESLSANADVDAVGINCGTGPVGVFDALPSVLSATTKPVVVMPNAGFPRDV
GGRMIYLTSPEYFTEYAKKYIELGVRGVGGCCGTTPAHIRMAARAIKTLSGVKRHIEVRP
VAREEIRVEQVPTREKSRLARKLCDGEKVTSVEIVPPRSSDMSDMLAKVRRCAEAGVDAI
NMPDGPRASARVSPMISALTILREVGIEPILHYCCRDRNLIGMQSDLLGGYAVGLANFLI
ITGDPPKLGDYPEATGVFDVDAIGLTRVASNLNRGYDIGGNPISPPTGLLIGVGANPCAV
EMEREIERYYRKIDAGAEFAITQPVF
>A0A7X9JVA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MHNNPFNKALLDPQMFAVSWELVPGRGAKEAAQERTLALAQRAAAGGKIHAVSLTDNPGG
TPAMSADFMGTEIKKMGIEPLVHLTCKDKNRNQIESQLYALDRAGIKNLLVMSGDYPVSG
YLGRPAPVFDLDPLHVLQLISEMNRGLEYPAGSGTIRHQPSNFFAGAVVSPFKATEAEQM
AQYYKLKKKIAAGAQFIVTQLGYDIRKFQEVLLFMKQNNVSIPLMGNIYILPFTTAKMMN
RNELPGSIVTDKLLAEIDHERTETDKGVGARILRASRMYAIMKGMGFNGVHIGGHNIKYE
QVEEIIQQGETLVPQWTDLIRYFDYPIANGFYYFERDPGTGLNRENPSNRQTGSREAKME
CSYGFSLFFHKLMFEPGKKLYGIMKNISRKAAGTKLENIFHKLEHLTKVLLFDCQDCGDC
ALIDVAYLCPMSQCPKNQRNGACGGSFNGWCEVYPGKKQCIYVRAYARLKKHGQKTQLEK
DIVPPCNWDLYQTSSWINFYSGKDHASKKYNTTSSGN
>A0A7C6KX24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterium sp|TrEMBL
MRNSENLCQKLKNKQFVITVEISTPKGADISNSIEEAKKLYGIADALNITDCPMANMRMS
PIALAHLLQNHLNIETIFHLTCRDRNLIGLQAELLGAYALGVRNILALTGDDPKRGDVPQ
ATGVYDVDSVGLVKIAKSLNDGFDYNGNKLESSTNFCIGTTANPNDLRPESIEKLRTKIE
CGASFIQTQPVYDDEILYRFLDAVEQFDIPVLVGVLPLKSYKMAVNLNEKVPGIEIPEKI
IDRLKNGEKGEGTKIAIEFINKIKDKVGGVHIMPLGKTDIVVDIVNGVKNMRQNDIEEVL
>A0A3M2ADJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIRDRLAHKCPVFSFEFFPPKSEAGDRVLFRSLRRLSGLRPDFVSVTYGAGGGTRRRTV
ELVRRIREDFGIEAMAH
>A0A661SXQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
ADHQKFGNHPEAKNVFDIDSIQLIHTVRTMRDEGKFLNGQDIDVPPKLFIGAASNPFAEP
FEFRVHRLAKKIAAGADFIQTQCIYNMDRFREFMKQVVDMGLHEKCYILAGVTPMKSVGM
ARYMAKSVPGMDVPDSLIKRLQGAGKGKVAQEGINFAVEQIQEFKEMEGVAGVHMMAIEW
EHKVPEIAEQAGVLPRPSF
>A0A2G6NGB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSDSTLEKILKAGHFAFTGELGPPRGSSVEAVRSKAKHLIGIVDLVNITDNQTARVRMS
SWAAALIVKEMGLEPNYQMVCRDRNRLAMQSDILGAYAHGIHTMLCLSGDHQKFGDHPQA
KGVFDIDSIQLINMVKTMRDAGTFLSGEAIDTPPRMFIGAAANPFATPYEWRVHRLAKKV
AAGVDFVQTQCIYNMDIFRQWVHQANDMGLTEKVHILAGVTPMKSIGMATYMQRNVPGID
VPDGIIKRLKGVEKKKVANEGIKIACEQIEAFKEMKGVAGVHLMAIEWEHKVPEIAEQAK
LTPRPDLG
>A0A496YIA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRLREALQRKRFVVTSEVQTPIDEDPQALIEKLELVRGRVDGVTVPELEIEGVVVDTVKT
CELLKKNRFESIYQTTTRDKNRIQLQKDLVVAHEVGVENLLVFTEDYRITGDSLQEIMFF
HVDVGKLESVLEHMREGYTVDGQELPFKAEFVVGSGIESGWGKDVPELEMKEMEQMAKIG
AGYFLTTPVFDVDMFEKFMKQVSTFGIPVIAEVMILRTAGMASFLNRHFKSGMVPDWMIK
KLAKAADREKASIEIFADIVKGLKDLCQGVHIITIGGEERLRYYLDAAKLR
>A0A496YP24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSRLEEVLKSGKFAVTAECGPPKGADPEAILKKAELLKDKVDAINVTDNQTAIVRMSSMA
ACALLKQNGFDPVLQMVVRDRNRIALQSDVLGAAALGIENILCLSGDHQSFGNQPQAVGV
FDLDSIQFVQVVREMRDNEVILGGDALSKPPKVFIGAAANPFGDPLGFRVVRLAKKVAAG
ADFIQTQCIYNLERFKKWMEMARERNLTEKVYILGGVTPLKSAKMAKYMKYKVAGMDIPD
AVLARLEGVPSKKQAEEGIKMCVETIQGLKEIPGVSGVHIMAIEWEAKVAEIVERAGLGP
RPTKGK
>A0A661T8X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSLQNQLSSGKFVVLAEMDTPKGVDISELVTNARRVKGRIDAVTIPDMADGIMRMSAIAG
CVLMQQHGIESIIQVYGRDRNRMALQGDILAAHVLGIENLLVVRGEDMVSGDHPDAKSVD
DLDELAILKAIQSLQDGIDMAGFELKGAPSFTIGCTIAPFADDEAMDAELALAAKKVEAG
ARFVITPPVFDLDKSIPFLEKTKDLGVPVIPTVFLLKSVGIARYMATNEPGVHISEEMIQ
RIRKSPNREMEGIKIAGETIAALKQLVQGVQIVTLGWEDQIPTILDHAGL
>A0A661T9H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSTKTPSKLEKILSQGHLAVTSEVGPPRGSDPEAIRKKAEMIKGHVDAVNITDNQTSVTR
LCSLAACIHLKLMGLEPTLQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQNFGDQP
QGQNVFDLDSMQLIQTIRYMRDEGKFLGGEEITRPPKMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNVDKFEEWMRLARDRGLHEKCYILAGVTPFKTAGMANYMKNRVPG
MDVPDEVVKRMKGVPKEKQAEEGLKICVETIQRLKECEGVRGFHIMAIEWEDKVPWIVER
AGLYPRPELAED
>A0A661S4M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSDLNTASNLEKVLKAGHIGVTSECGPPRGSDAEEVKKKGMLIKDHVDAINVTDNQTAMT
RMSSLAACVHLKLMGIEPVLQMVTRDRNRVALQSDILGAASFDIPNMLCLSGDHQSFGDC
AQGQNVHDLDSMQLIQTVRHMRDEGKFLGGDDIKRPPKIFVGAAANPFADPFEIRVPRLA
KKIACGAEFIQTQCIYNIDKFKEWIRRSVDRGLTEKTFIMAGMTPMKSVGMAKYMKNRVP
GMDVPDEIIARLAGAEKGKQAQEGIDICVEHIQELKEIKGVSGFHIMAIEWEEKVPEIVE
RAGLYPRPEV
>A0A4R4UQX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora aridisoli|TrEMBL
MPFGSTEEEVLAHVPRDVVLTVTTTEARGLEPTVDLAVRLSKNGYATAPHLAARLVRDRA
ELDEIAARLLESGVDRVFVVGGDAAEPAGEFSDAEGLLLALAEGGRDFSHIGIAGYPEGH
GTIPDSVISEALRRKAVHAHEIVTQLCFNPATTTGWAGRLHDSGITTPVRVGVPGSVNRQ
KLIRVSAGLGLGQSARFLAKQSAMFWRFFLPSGYRPDKLVAGLTDQITSPGNAISGFHLF
TFNDLARTERWRQDRLAALS
>A0A2E1A259|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSRHRKHQPSPLYRLRHETPMKLIDLYRRKSFVFSIEVFPAKTAEGMETLKQTLGTFAKF
RPDYFSVTYGAGGGTRENTHALATHLQNKLGIETMAHLTCVSHTGQEIEVVLRQLEKSGI
ENVMALRGDPPQGSTEFRRPENAYNYACELVAAIQKRGGFGIGAAGYPEGHIENPDQDAD
RHFLVGKINAGVDFIATQFFLDNSFFLRWRDQLAADGVSVPLVPGLLVPTSLKQLTRMAD
FCGISIPNKLRIQLETHHTDPEAMKQIGLEHTSRQLENLLREGIPGIHLYALNKLATVQH
LAPLLPYSSKNLLAPCAA
>A0A661I449|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MFDTLLDKLQNDNYLTLETTPSHEPIFDNIIDKIQQYDLASKVDGFSTTDNPLAKLKYNS
LFAALKLQQKFNKPVIATMSMRDRNKIALQSDLLGANDFDIRSILALTGDPAKMSDQPHA
KGVFEDNSQMLLKIIKSFNNGMDYSGKPFKSAPKTILPFSVINSYAKNFKSLEKKMNKKI
HDGAVGIISQPVYGIDNAKKLLNHFDLAKEEFNDERKKSQLILGIFPITKLRTAQFLSSH
VPGINVPDNWIDALTKASKISVDEEYKVGMKLSNNLLKDIQKLHPKIHLMTANKFDIASE
LLD
>A0A661M2S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSADVSTNTPSKLEKILRAGHLAVTSECGPPRGSDSAAILKKAEMIKDHVDAINITDNQT
SVTRLCSLASCIHLKLAGYEPVLQMVVRDRNRIALQSDLLGAASFDINNVLCLSGDHQAF
GDNPQGQNVFDLDSMQLIQTVRLMRDDGKFLGGDEIKRPPRMFVGAAANPFADPFEIRVP
RLAKKIAAGAEFIQTQCIYNLDKFKEWMKQARDRGLHEKVFILAGLTPFKSAGMAKYMKN
RVPGMDVPDEVVKRMSGVPKEKQPEEGIKICIESIQRLKEVEGVKGFHIMAIEWEEKVPR
IVEEAGLYPRPQA
>A0A2N2HC89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-21|TrEMBL
MKEMSRLKAVLEKGGFAVTAECGPPKGADPDTVLRKGQLLNGKVDAVNVTDNQTAIVRMS
SLAACTLLKSAGMDPVLQVVVRDRNRIALQSDILGASALGIRNVLCLSGDHQSFGNQPQA
MGVFDLDSIQFVQTVRSMRDQGLVLGGDKLSRGPDVFIGAAANPFADPLAFRAVRLAKKI
AAGAEFIQTQCIYNLERFETWMGLVRDRGLHEEAFILGGVTPLKSAKMAKYMRDKVSGMD
IPDQVIERMEKVPPGKQREEGIRICVETVERLKEIPGVKGVHIMAIEWEDAVGEIVEKAG
LLPRPS
>A0A318BDS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. 3335mG|TrEMBL
MSLPSIHPNWDLPLERMTDGYSLEMTAKDVDALTRAAPDIAPETPVAITFLPGESLESRI
AAAKQVRALGFEPMPHFSARRLTSDSDFERYLASVVAEAGVRRCFVIAGDPPEAAGPYED
SMALIRSGAFERAGIRAIGVGGHPEGHPNMTAEETFGVLIAKCDEIAKRGMAPLIVTQFG
FDAAPILNWLAELRVRGIDAPVRIGVPGPAGIKTLMRFAARCGVGASASVLGKYGISIGK
LIGSAGPDKLVDALARGLGPQHGKVRLHFYPFGGLETTVGWINDYGARH
>A0A3D5HEP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEILTTISDSFESDRFMEPADDLQENIEQNTTWSMEILPHNIAEVSLIPEFINEIYITMI
PGATCLEAIEAAQKIQAVGKQAVPHIAARSFTGAEDLEECLSGLEAAGIERALLIGGGHS
ELAGKISCVMDMLKTGLFAKYGINAFDFAGHPEGNPDDPNSAVHMLEKLRWAEEQGASAR
IVTQWSLDTECTNAWISGLREKGVNNPIHLGIPGPSTLKTLMRFAKICGVKASTTVLRKQ
GLNLSKLMFVNKPDKIIEELRGYDQLHLFPFGGIERSSAWLTEWQTKSYI
>A0A534VJM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKISQRYTEGRPVVSFEFFPPATAAGEEALMRTIDALRPLGPGFITVTRTGTKPREAPVE
LVTRIRALGLEGAAHVTCIEASRDEIAAHCALIARRGIENVVTIRGDRPKDPGFRPPANG
FRYALDMIRFIRERGHDFCLIGGGHPEGHPECRDRERNIEHLKMKVDAGLDVVITQLFYD
NADYFGFVERARRAGIGVPLVPGIMPITNWPQIERITALSGNQVPPRLRAALERVRDDEP
AAVAVGVEWATRQCAELLRAGAPGIHFYTLNRSPATRAIFENLRREGVIPS
>A0A661T413|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNDYKSESNLEKVLRSGQFAFTGECGPPQGANVEVLKEKAGHLKGCVDAVNVTDNQTAVV
RMSSWAASLILLQEGLEPNFQMVCRDRNRLAIQSDILGVSAHG
>A0A661SL68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLKEALKTKRFVVTSEVQAPMGDDKPEELVENLKRVRGRVDGVSVTEVELEGIVGDSIK
TCEILKENRFDAIYQTTTRDKNRIQLQKDLTHAHEAGVEHLLVFTEDYRITGDSLQETMF
FHVASCKLASVLEHIRDGQAIDGQELPFKADFVLGSGVESPWGQNVPKQGMQEMEAMQNM
GTGYFLTTPIFELDQFERFMKQVNTFGVPVIAEVMILRTAGMARFLNRHFKAGLVPERVI
QKLSNAPDKQQASIDIFTETVKGLKDLCQGIHIITIGGEEKLMKYLDAAKLR
>A0A496Z409|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSNLERILEGGQFAVTAEAGPPKGSSPKVIQRKGELLKLCCDALNVTDNQTAIVRMS
SLSGCVLLKELGVEPVLQMVVRDRNRLALQGDILGAAALGIRNVLCLSGDHQRFGNHPAA
KGVYDIDSIQFIQMVKTMRDEHRFLNGEEISGDVPFFIGAAANPFADPFEFRVTRLAKKV
NAGADFIQTQGIFDVPKFVEWMKMVRDRGLHEKTHILAGLIPIKSVGMARYMRNNVSGLS
VPQEIVDRMADAKDAKEEGVKICLETIEQLKEVEGIHGIHIMAVAWEDIVPRIVEEAGLM
PRPVV
>A0A0B4CV83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium taiwanense|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRLTRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTNGGHASAMDLVHQINDLGRGKYLHNQDEVCDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVTKAREMGITVPIIPGI
KPIATKKHLKVLPQIFKIDLPEELINEVEKAKNNEAVKQIGIEWAINQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A3M1TIR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MAERSLSFEFYPPKTDAGRRRFLRTLDALARLEPSYVSVTFGAGGSTREKTFETVELIRA
RTRLCAVPHISCITSTRDEIHRYLKRYVDAGIPKVVALRGDRPRDGSPLPPRGEGFRYAA
ELVTYIRRHFPSLRIAVACYPECHPESPTPHSDLRHFAEKVRAGADAAITQYFFNNAAYY
RFRDEAAALGVDIPIYVGLMPIWDWAQVRRFSEFCGADVPRWIRRRMDAFEGDAESQRAL
GVEIAARQIEDLFAHGAPGIHFYTLNRAEPILRIYEALGLR
>A0A351T0P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MPSEESPVKLCDIYARPGLTFSVEFFPPKTEKGDKGLFKEIAVLKRLNLSFYSVTYGAGG
STREKTLDLVDRIHREYSMEVMCHLTVVGQSRDEVRSVLAQLKERNIENIIALGGDPPQG
VVEWTPNLDGFHHSVELVREAAAYRCFSIAVAGFPEVHPRSGSREEDLRYLKEKVDAGAD
VVITQMFFDNEDFCRYVEDAKKLGIRAPIVPGILPILSAPQVRRFTALCGAKIPPRLERM
LARVEDDEEGAVRMGIDYATKQCEGLLALGVPGIHFYSLNKSRSVKAIFANLNL
>A0A423PTN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinisphaera orenii MK-B5|TrEMBL
MTAEQALGRALRRPRYEIIPMRGALEAARALPAHAVVTVTCSPTRGIDATVELAAQVAAL
GHVAVPHLAARRFASRSHLETGMSRLTEAGVRDVFVVGGDGDHVAGPFDHGCRLIEALAE
IAPGLRSVGVPCYPEGHALIAAETLDEALDAKCFLAGHMVTQLCFDAARIRDWLQGVRGR
GVDLPMHVGIPGVIERRRLLGIALRIGLGDSTRFLRGNKRMWGRLTGPSQFTPDALLDDL
APLLAAPELNVAGLHINTFNQVGSTEAWRRKRLSALASTAGDVDASGSPSSAAPDGRA
>A0A117PW78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces yokosukanensis|TrEMBL
MTTFSFEFFPPKTAGGEQALWQSVRRIEPLAPDFVSVTYGAGGSSRERTIEVTKRIVAET
TLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPKGPWEPHPDGFTYAYQ
LVELVRSLGEFTVGVAAFPEKHPRSPDWDGDIRHFVAKCRAGADYAITQMFFDVEDYLRL
RDRVAAAGCTTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAARERPDEAYRIGV
EHATAMADRLLAEGAPGLHYITLNKSTAALDIHRNVLNSSRSLHVS
>A0A520RMB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|OM182 bacterium|TrEMBL
MFESQNFLFTAETTPDVSTDLAASAGRVDDLVGVADAINVTDSPNSKTRLSSLLVAAEIR
RKGLDVILQLTGRDRNAIALESELLGALSAGVNKVLCLTGDQPPEGGPKAVNEFNGAGLI
QLCNTLSQGTLSDGTPIKAAKTVYPGAADDIYQHLDNENAAAGLLRKIEDGAGFVQTQYC
FDLDVIKAYAKKLSETPAFKDRKVLVGLGPLASAKQADWMRKNLWGVNISDDIVQRLEQS
HEPMREGEAICEELIGELMQLPEIGGVHLMGPNCEKRSARIIARFRS
>A0A165NI28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fictibacillus phosphorivorans|TrEMBL
MSLITDLEQNKILIGDGAMGTLLYSYGSDFCYEELNLSQEEQIYNIHRAYLDAGADIIQT
NTYAANYSKLERYGLQDYVKEINKAAVQIARKAAQSEYVVGTIGGIRGIKPNSISLDEIK
RSFREQLYCLLMENVDGIQLETYYDLQELETVLEIARKETSLPIIAQVSLQEVGFMQDRT
PISDALKSLESLGADVVGLNCRLGPYHMLMTLEEVAIPNRAYLSAFPNASLPSYTDGRFK
YEGDADYFKECAHLFRQQGVRLLGGCCGTTPAHIRAFSDELKHLEPVTEKEVKQRKRKVV
IQSAPKPKYVPLSEEVKTKQSIIVELDPPRKLDTSRFMEGAKALKEAGIDALTLADNSLA
SPRVCNSALGSIVQSQLNLRPLVHITCRDRNLIGLQSHLMGLHTHGIHELLAVTGDPASV
GDFPGASSVYDVTSFELIKLIKQFNEGLSLSGKELGEKTSFTVGAAFNPNIRSIDKAVER
LEKKIAYGADYFISQPVFSEQKLIETYEATRHIDKPIYIGIMPLTSSRNAEFLHHEVPGI
KLSDSVRDRMGKYKEDPKQACKEGLSIAKSLLDTAMELFNGIYLITPFMRYELTVELAHY
AKANHPSLLARRSQNA
>K6W716|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Austwickia chelonae NBRC 105200|TrEMBL
MSRPSIPDLLSAPEATFSFEFFPPKSDAAEDALWHAIRRLEPVSPAFVSVTYGAGGSTRD
RTVRVTERIAKETTLRPMAHLTCVSSSVDQLREVVGQYAAGGVRDVLALRGDPPGSPGTP
WTPHPEGLDHAEDLVRLLRSLGDFTVGVAAFPDKHPESADLDADADVLARKFEAGAEFAV
TQFAFDVDSYTRLRDRLAARGWENPIVPGLMPVTSYKQVSRMAELSGTSLPAAVVARLAP
LEEEPEALRAEGVQIATELAESLLAEGAPGLHFYTMNRSTATLQVYRNLVGGAPELAVPL
QVRPDLLRGGVVASVLRIVHAVDAQDWRAVRECLCERVVAEFPAQGVRIQGAETLMGVIP
GAFERLSVERVVYDGGLQAVLWISRDGAGGERVHDALFICLDHVGRIESVVALRPGT
>A0A8F7RII4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A7I6TA77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella sp. WP7-S18-CRE-02|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1W9TEQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetales bacterium 4572_13|TrEMBL
MSHRLNDCLNSGEFAVTAELTGSPGYNFSPIEKFLSAHQEKKAAVPGGFSFVGITVPQNP
GGVANIDPSDVLAVIEKKNLLGDLDYIPHLSCKDNNVDSLTSTLVGYRQRHIESVLALTG
DKPITSQGVFEVESIGLLSLIGQLNHQSITKAKPGQWDQVHQFYAGAAVSPFKYTEASLM
QQYYKMEKKIAEGARFLVTQVGWDWKKSLELARYCKDNNITTPLVGNVYWLTTKTPAPRL
MHDIKLPGCFVSDDLLAKLQAETVDEHIERAAQQVAMYQSMGYAGVDIGGVHDYDVFLKI
LNRATEIGDGWEQYKDNLYWPAEKPFYLYDEAGRQVSLSKPKRKCNERFFDFMHRAILDS
DYKGFHCLKWVLKLFRVNKESGFTYKAFNAIEKSFKYCAFDCAECGDCYLPENFGYCTIG
GCEKGMDNAPCGDSTVDGYCGNNLERLCIGERIYDSAAAKTDGREKLRTMLNKPRIAALE
HTSSIVNYLFGKDHTMTTPLIGIGESIHASIPKTGKIMKELHDLGADAYTKESGPLNYIR
ALVEEQADDDAAYIAVNLDAFGESDPQQAVGMMVDYTKLVRQWSKGVPICIDSSNDDVLI
AGLKEWYNTDEVVKPPLLNSIKTHTTDKMMALKKTYDFSFIGLLVSEDKATGPGGSHSVE
ELFGLAKEIFDKAMQYGFKPEEIYFDSTVFPIAIDMPMEPGVPGYTYRAFETIKKIKTDP
QMKNCHCSLGLSNSCRDLPGRRIGIARAYTAKAMEYGLDAGIVNVTHRFGEKPADPGLVE
LVDAYAKLDGNMDNLTVAMERMGQFCQSCKKPS
>A0A8H6YNR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycena venus|TrEMBL
MRVIDKIKDHGPSNPFFTFEFFPPRTDQGFENLISRISRLSALNPLAVSITWGAGGSTRE
RSLDLAGVTQVEHGLDTILHLTCTNMEKGMVDDVLKAAKERGIQSILALRGDPPRGQEEW
TPTDPRFAHGADLVAYIRSLPEYSSQFCIGVAGYPDGHTGELSDERAEISFLKAKVDAGA
DFIVTQLFYDVDGFLQWVRKVREAGITVPIIPGIMPIQTYSSFLRLTKLCGTRVPDSVMQ
ALEPIRNDDQLVKDYGVKLAVEMIRRLTTEGGIPGVHMCTLNLEKSVQRVLENLEWTGSF
EIVPKNKLIEEVPTQNELTVTPSSATSSATLGLAALPPVEGEAGRGELNNAATWDDFPNG
RFGDFKSPAFGSSGLWGGPAIGHADIIAQCGHPRTLDDLTAIFLAHLHSKIPITPFSPAP
LSPESLMILPHLERLTRRGWWTVGSQPAVDGASSGDEVVGWGPRAGYVFQKGFVEFFCTK
ADVDATERRVSERGNGWVHWFAGNKNGECRGNVPEGGRNAVTWGVFPGQEVAQTTIIEQE
SFLSWKEEAFSIWSEWASLFKPQSEERRLLESVCDERWLVSIVHHDYRNTQALWTFLFDD
SPIA
>A0A524H0L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MPDLRQLLADGHVHVSDGAMGTMLYSKGVFLNVCYDELVLRQPDIIRDIHRAYVRAGAEL
IETNTFGANPIKLAHHGLSDDTEAINEAAARLAREAAGERASVVGAIGPLGIRIEPFGET
SVEEAQAAFARQATGLLAGGVDGFLLETFSDVEELRAAVTAVRRLSDLPIIAQMTVGEDG
RTHYGTAPSTFGPAIAAMGVDVIGVNCSVGPHGVLEAIEHLARVVTLPLSAMPNAGLPRD
VGGRKMYMASPEYMATYAKRMVEAGARIVGGCCGTTPEHIKAIVGFAQSASPRHAHTTVA
PAAAQGVPALPLGQRSKLGAKLASGEFVTTVEIVPPKGVDPAPMYAQVRALKAAGVDAVN
VPDGPRAQSRMGALLSGLLIEREVGLEAVVHYACRDRNLLGMLSDLLGAAAAGLRNLLII
TGDPPKMGPYPDATAVFDIDAIGLTNLVSRLNHGLDPGGNAIGAPTRFVIGVGANPTAPD
FEREMSRLAWKVDAGAEYVVTQPVFDLDQLDRFLDRTSKHAIPVIAGLWPLVSLRNAEFL
ANEVPGVSVPVAVLERMRIASAVGREAGLAEGVQIAREMLEAVRPRVQGVQIAAPLGRVP
VVLEVLGPR
>A0A645AUL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MKILELIDQTSKPVFSFELLPPLKGNSIKQVFGTIDRLKEFGPKYINITTHHSENIYKEE
EDGTIRKVNVRRRPGSVAIAAAIQNKYGIRAVPHIISQGFSREETEYALIDLSFLGVTDL
LLLRGDTKKLDADQRNMDSHPYVTGLQEQVNNFNKGIAFDGSAFPVPETPFTYGMACYPE
KHEESPNMESEIHYTKMKAQNGADYLVTQMFFDNQKYFDFVDRCRVEGITIPIVPGIKPI
HLKNQLNVLPKIFRTEIPEDLERELRKCKTDADAVEVGVEWCLLQSKELAQRGVPGIHFY
ALGATESIYRVAKEVY
>A0A838P5W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
NTFGANPVKLATHGLAGDTERVNSAAAGLAREAAGERASVAGAIGPLGVRIEPYGEMSVD
EARHAFARQVRGLLAGGVDGFILETFSDVAELGAALQAVRSQCDLPVIAQMTVGTDGRTH
YGTDPEVFGPELEALGADVIGVNCSVGPHGVLEAIEKLARVVSVPLSAQPNAGLPREVGD
RKIYMASPEYMASYARRIVEAGARFVGGCCGTTPDHIRAIRGFVQSVSPRHVHVVAAAAP
QHSAGVDPVPLAARSRLGAKLAEGRFITTVEIVPPKGVDPAPMFTQVRQLKAAGVDAVNV
PDGPRAQSRMGALLSALMIEREVGLEAVVHYACRDRNLLGMLSDLLGASAAGIRNLLIVT
GDPPKMGPYPEATAVFDIDSIGLTNLVSRLNRGLDPGGNPIGQPTRFVVGVGVNPAAPDL
DRELKRFAWKVEAGAEWAITQPVFDLPQLDRFLERTQTLRVPIVAGIWPLVSLRNAEFLA
NEVPGVSVPESVLDRMRRASAGGKEEALAEGVRISQEMLAAVAERVQGVQVSAPLGRVSV
ALEVLSAAPIEPAVTHGYTPGT
>A0A428ISZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQITDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2W6LFB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSAGLSLRAEAFINAFSLEVSAKAMPALRAEADRIPRGTVISIPWLASEDDDARLAAVRT
VRALGFEPMPHLSARRIRSAASLARFLERAAGDAGVARCLLIAGDLATPAGPFADSASII
QTGLLEHSGIKVVGIGGHPEGHPVMSSDERWQALERKCQSIEARGMAPLIVTQFAFDADA
VLAWLEALRARGISVPVLVGVPGPASVSRLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDCLVKGLTRAHGQVSPHFFPFGGIAPSLEWVAQYRHHISISQRR
>A0A094KW77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Antrostomus carolinensis|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEADGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGVWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A1Q8A029|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_1_20CM_2_66_18|TrEMBL
MRIADMLGRSKPTISFEFMAPRDESEVEVLERTVATLAGHAPDWVSVTYRVRTGEKTLEL
VTRIKRHYHIEAMAHLTCANSADRTRQILNWMEREGVANVLALRGDPPISGEPFTPVDPQ
LTHGSDLVSLVRRSGYRFGIGAACSAEKHPESPDVEHEFRYMKLKVEAGADFLITQLFFD
NRFYFNLVSRARAAGIGVPIVPGLMPVPSRRSLGVMTAMSGATVPAELQSAIDNAADDDA
VRALGVQHCIAQCAELIEARVPGLHFYTFNRARAPIEILAALRGQQLLAS
>A0A428IKV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSTNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2W5HEI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
PYLASEDDDARLAATRTVRELGFEPMPHLSARRIGSRAALARFLERAASEAGVEKCLLIA
GDLTTPAGPFADSISIIETGLLERYSIKVVAIGGHPEGHPAMTAEDRWRVLERKCQAIEA
QGMAPLIITQFAFDADIVLAWLDALRARGITVPVLVGVPGPASIARLARYAAMCGVGASA
SMLARYGISIGRLLGTAGPEVFVDRLLSGLTDAHGAVSPHFFPFGGIAPSLDWIERYRRR
ALAASD
>A0A2M7S3J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG_4_10_14_0_8_um_filter_37_32|TrEMBL
ITILKSVGMAKFMNANVAGVFVPDNLIEELKKDKEKTRSGETGIEIAVRLVKGLKPYCHG
IHIMPLGWDSKVPEILSQAGL
>U5Q604|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium CF|TrEMBL
MKVVEHIEKSQGRTLCSVEILPPLKGQNIESTFRGLDPLIEFNLPFIDVTYHREEFEYTE
YPDGRLEKRIVRKRPGTVGICAAIQNRYKIDAIPHVLCGSFNKEETENFLIDLGFLGIDN
VMALRGDSLKNETYFVPERNGNRYATELVSQISDMNKGIYLDKELLDTAPTNFCIGVAGY
PEKHMEAPSLESDIHFLKEKVRNGADYIITQMFFDNRKYFDFVDKCREEGITAPIIPGIK
PIATKKQLNMIPLRFKVDLPDELVKMIVKAKNDDAVKQIGIEWCTEQCRELMKAKVPVIH
FYATGRTENVREVISRIQ
>A0A0R0B5M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAPGSLRTEAFISTFSLEVSVKAMPALRAEAARIPRGTTISIPYLASEDDDARLAAARM
VRALGFEPMPHLSARRIGSRAALERFLERAASEAGAEQCLVIAGDLATPAGPFADSASII
ETGLLERFGVKVVGIGGHPEGHPVMSSDGRWQALERKCRAIESRGMAPLIITQFAFDADI
VLAWLNVLRARGINVPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGVSIGRLLGTA
GPEVFVDRLVQGLTDAHGLISPHLFPFGGIAPSLDWIERFRLRGPFPRVRR
>F0JXG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia fergusonii ECD227|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0H4R0F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus ginsenosidimutans|TrEMBL
MAKNTTRPRLSFEVFPPNSKVGVENLTSTLDELRNLDPSFISVTCSNHKLDYEKTTIDLA
KYVHDSLKCPTMVHMPAAYVTKTQVARILDELEELNINQVLVLRGDIIDGFAPESDFKYA
SDLTKFIKQQKPFFEVSGACYPEVHPDSKNRIDDVRHLKEKVDAGCDQLITQLFYDNEQF
YRFQEECAIAGINVPILAGIMPIVNRKQALHVVENCSAHLPKKFLAILDKYKDNPVALKE
AGIAYAVDQIVDLVTNDVDGVHLYTMNKSDTAKHIYENTASLFNLAPTAELE
>A0A3R8QLH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium paraconglomeratum|TrEMBL
MSERSPGRPPPVADRAGTSATSGPGGSPPPNPASRQAQFEVIPLPGIAERALEHLPAGSR
VTVTASPAQGLEATLEAATALAAGGMVAVPHLAARMVEGPDALERILERLGGAGIEELFV
IAGDATPPAGPYDGALTLLEAIAPAGRGLVVGVGAHPEGHPHADPAAALELLRRKAEHAS
YVATQMLFSPDPLLTWAEQLREAGIDMAVRPGVAAPASRTRLLRIGTRIGVGRSLRMLTA
ESSGVRRLLGPGHWDPDPLLDALAAAELPGLAAPHVFTFNSLAETAAWWQARIGRA
>A0A1S2MRD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. LCT-H2|TrEMBL
MSSTFDASRASRVPFSFELYPPRSESSQEALHETVRRLAAAGPEFLSVTYGAGGSTGGRS
LDVLRFIREHTDVEPLAHLTCVGNTYAGATALIREFLDAGILRFLALRGDPPAGQSEPFL
GDLESAAQLVQLIDRVQAERAPYQESPVPGLPGAALVAPRQKVDIAVAAFPKGHPRATHR
TQDVEALLAKQAAGATFAITQLFFHPDDYLAFVERARAGGVTIPILPGIMPITSPARLAR
VLELTGEDLPSELSVALDVEPTAEGRREIGISWAARLAADVVAGGAPGVHLYAFNQHETV
LTVLAEAGIVPALRH
>A0A1V3DBA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RTEHGDAFHIEVGAYPETHPQATDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWIGRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLRG
>A0A421BE34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atopobacter sp. AH10|TrEMBL
MSIQDLFKEKTVLSYEVFPPKKQAKNPSSIYKTLDVLKDLNPDAISVTYGALGAKNNTET
FKIAKTIKDYGVESIVHLPGIELTKADVLEKLDQLKALNLHNILALRGDLPEGDFTPGDF
RYASDLISFIKENGDFNITAACYPEGHVDSPNIVEDIKNLRIKVESGVDHLITQLFLNND
HFYRFRERCALAGINVPIEAGIMPVTNKRQIEKMTSLCGVELPEKFIKVMNRYEDDPIAM
RDAGIAYAIDQIVDLVTQGVDGIHLYTMNNPYIAKRIFEATHNLIDHRAKVIANKNLPKV
AQI
>A0A246HLN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAAKLKVFAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFDAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASELISFI
RAEHGDAFRIEVGAYPETHPQANDALLDLKHFKTKIDAGADAAITQYFFNADAYFHFVDA
VRKLGVTVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAESVRAFGAEVV
ASLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLRS
>D2QA88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1)|TrEMBL
MHSPLFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGRSSDRTLTARIAHTVS
EYGIPCVAHLTAQYLNKDDVDQALDMFDEAKVSGVLALRGDRVEGAEPAGVFEHASDLAA
YIREERPNLKIYGACYPEKHPQSATLEDDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KVRAVGIEIPIEAGIMPVMNAKSVRRMAGICQSRVPEKLEVMLDKWGGDNAVLKEAGIAY
ASEQISDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A828SBT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium acnes HL043PA1|TrEMBL
MAPDFISVAYGANGSRCDRALRCTQHMVSTGLRTVGHLTCVAQSVADVEQMVADYAESRI
DHILAIRGDMLGGAGQPWVAHPWGLPNATELVRLVKWVHPEACIGREGA
>A0A0Q3TSP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacillus sp. FJAT-21963|TrEMBL
MGLLEKLQTNVLTADGAMGTLLYSYGIDYCNEELNIQKPEIIEKIHQDYIVAGADIIQTN
TYGANAIKLARYGLENQMKEINEAAIQIAKRAAAPGGQFVLGTIGGIRGIRKSDATIDEI
IATVNQQATQLLSGNPDGLLLETYYDFEELSATVTHLRKLTDTPIIAQVSMHEPGILQNG
LSLNDALHQLEALGASIVGVNCRLGPHHTIQAFEGVTLTEKAFLSAYPNASLLDVEDGRI
VYESEADYFGKAALYLREAGVRLIGGCCGTTPKHIEAVKKRIGTLPPITNKIVTPRKPII
IQEAEPTVNQPLHEKAKTERTIIVELDTPRHLDTTTFMEGAEKLNAAGIDAVTMADNSLA
SPRISNMAMGSMLKLQNNIRPLAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKI
GDFPGATSVYDVSSLELLQLIKQLNEGVSFSGKSLRKKANFSVAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVYSKEKMEEIYEATKHLSSPIFLGIMPLTNSRNSEFLHNEVPGI
KLSDEVLERMRACGEDKERSTEEGIQIAKELIDTAAELFNGIYIITPFFRVDMSLELIRH
IKEIDGKKARENSYVQTSN
>A0A7Y2CB75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermales bacterium|TrEMBL
MKITELLDNRKETLISYEIIPPARGGSIQEIFQMVEALVPFDPPFIDVTSHSAQVNYEEM
PDGSWQRRVKRKRPGTLGLCASIRGRYGIETVPHLLCEGFTREETEDALIELNYLGIKNV
MALRGDESGYSKPLPPTRSRNEFAVNLVDQIVDMNQGRYLEPLIDPATADFCVGVAGYPE
KHFQAPNLAWDIANLKRKIDAGAEYVTTQMFFDNQHYFAFVDQCREAGITVPIIPGLKIL
TSKRQMRMLPTNFHVDIPEEVSSEIEAADPADVAEIGINWATKQASELMDAGAPCLHFYI
MKTAKHVTQVVNRLRQYA
>A0A0V1PUQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Debaryomyces fabryi|TrEMBL
MRISEKLLQAHSTSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALHKAYISGCQNILALRGDPPLD
GSESTGDFKYAKDLIKYIRNKYGDHFNIGVAAYPEGHPEEEDEEKTLQYLKEKCDAGANL
IITQMFYDADNFITWCSKLRKIGIDIPIIPGIMPISTYAAFIRRAKWSEVLIPQHFLDTL
EPIKEDDYLVRAKGTELVSEMCRKLIKSGYVNHLHFYTMNLERATIMILENLNLIESVKS
HEVIGGSDLPWRKSLHPQRSKESIRPIFWQNRKYSYISRTSTWDEFPNGRWGDSRSPAFG
DIDLFATDLLRQSPKKAFDLWGHPGTLKQFSEIIISYLNGKLNSLPWSDSAIGEDSAIIV
DNLVALNKKGFFTLNSQPSLNSVKSNDKVYGWGPKNGYVYQKQYLEFFVHRDILPALLHQ
INNYNMSQGDSNSSILTYYAVDQKGKLSSNTKDDDINAVTWGVFPGEEILQPTIVEKVSF
LAWKDEVYRLITEWIKIFQSDFVKDVNITKEDADAFIELMTKFNDEYVLCNVVNNNFIDD
NQTIFKLIDELNIPDLK
>A0A4P9C5J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium maltosivorans|TrEMBL
MTIPEIMKNRMSFSFEVFPPKEEQPLEPLLDTLDHLYAFKPDFISCTYGAGGTNAGRNVE
ICKAIKDSGATIPITHFTCIGNSKDKIRDELRNYLSLGVDHILALRGDFPKGSASTGGDF
DYANELIAFIKEAFPEFSIAMAGDPEKHFEASSFDEDIAHLRIKQDAGADFIMTQLCHDV
AHYEWWVEKIRKAHITLPIDVGIMPVLAKDPTIRMAVSNGSSIPRDLAEIIARYGDNPKD
FKKAGVEYTVKQIHRFISAGIDGLHIYSLNKWADISEIVRAAGIR
>A0A3Q9IP70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricimonas faecalis|TrEMBL
MKVIDILNNTDKPVFSFELIPPLKGGDINKIYEAIEPLIALAPPFINITFHRDEVVYREY
PDGTIKKVTITKRPGSVALAAAIMRRYNVDMVPHIVCGGATRHKIENELIDLNFLDIENV
MALRGDPIPGERFFSPEDGGHRYSCELVEQITRMNHGQYLDDTLTDTVPTNFCIGVAGYP
EKHYEAPNQACDIENLKKKVDAGANYIVTQMFFDNAKFFQFVDKCRAQGINVPIIPGLKP
ISTLKHLEMLPRTFSIDIPHELVKEIRSCKNTKEINQIGIEWCVAQSKELIAHGVPAVHY
YTMGKSENIQEIVKQVF
>A0A367EWZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces diacarni|TrEMBL
MAIGISAPRTDRPPTVRDKLASGEQSFSFEFFAPKTEKGERTLWNALRRIEAVSPTFVSV
TYGAGGSSREGTVRNTERIANETTLTPVAHLTAVNHSRTELRNVIGQYADAGIRDVLALR
GDPPGDPLGEWVKHPEGIGYAAELVELIKESGDFCVGVAAFPEMHPRSTDWDSDIRHFVN
KCKAGADYAITQMFFRAEDYLRLRDRAAAAGCPTPIIPEIMPVTNVKQIERFAQLSNATL
PDGMVERLRAVEDDPAAVRSVGIEYATDLCARLMAEGVPGLHFITLNHSTATLEIHQNLG
LRQKAQLP
>A0A5N8YK08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium AC-647-P02_OGT_505m|TrEMBL
MNMISQLHRTLDSGSFAVTAELTLPDSSEKDELVETALKLSPYCDALNVTDATSAIPHFS
SLAAAYILLDNDIEPVMQISARDRNRIAIQGDVLGAHSLGIRNIFCITGDGVTAGDHPDA
KPVFDLDSISMLAALNNMDKTGSFMSGRKITPNPRLFLGAAANPFAPPHSYRPHRTIKKW
KAGASFFQTQFCFDIGVMKRFSEKLVELSDGNPPPVLVGLGPLKSSKMAKWLRDNIAGVS
IPDRIIERMDHYPEKEQAQIGLEISKEAIDDLKSIQGVAGVHIMAYRWEEAVKELVEDSG
LSKTNRL
>A0A1D7QEF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter steynii|TrEMBL
MKIVDHISNAKGTPLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HPNGLLEKIAYRKRPSTVATCAAIMNKYNVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDSSFVPTPDGHAYASELLQHVVDMNNGRYLHDYMEDAAKTDFCIGVAGY
PEKHYESPNLDTDFKYLKHKVDTGADFIVTQMFFDNKKYKALVDKCRANGINVPIIPGLK
PITSSKQLVSLPKIFHLDIPMELSEAIQACKSEKDVKEVGIEWMIHQCQELKEMGAPVLH
FYTMGNPEPTKKIVQAVF
>A0A378SLT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium gilvum|TrEMBL
MTQPVTERDAGRDCPKRMTFGPCGGVHPDGQCEMRPGPCAFPDIVPWPTQAAPPPVTAPL
ILTDFSCTPFDPHDVAATANALAPSCDAVLVGEHQNRPDFPPTLMSRLLLDAGVTPWITL
SCRDRNRVVLEQELRGLSLLGVQTVLCVTGDGRAYDVRPDVTQTFDLDGPRLVELAASLG
MVAAVPETPTAPPVARRPLRLVQKQHAGAGIAVLNHVSSPSTVAEFMAAARAAGLVIPVL
AAVAVFTDDVSAAVLQGLPGLALDPAVVDRVLAAPDPVEAGIEAAVAEARALLAIDGVAG
VNVSGLASGAGTRVGAQIKAEVGARIRAERSVR
>A0A1E8B2A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANIAPVIAKETVPWPKVVH
TQEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGMRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A812AEU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon GB37|TrEMBL
MQISIRDKNRLAIQSDILGAVTLGVKAFFCLEDCHQRVGDNPGAKGVFDLDCVQLISIMK
KIEHSLVGTRINPFAHPLELHLVNLSKKINAGVDFIQTMPVFDLERFKEFISLIKGENLY
LLAGVRPIKSWQALQSMSQMVIPENIVQRIKNTPENKQAEEGIKICVEIIKALKQIKGVN
GIHIFAHDWEEAVPILVRQANLK
>A0A2T0XSV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinilabilia salmonicolor|TrEMBL
MSTVAELIRNSNTPSFSFELLPPLKGNSISKVFNTIDKLKEFNPLYINITSHRDEVVYKP
NADGVNIPHVYRKRPGTVAVAASIQHQYKIPVVPHMICSGFTQSETEYALIDLNFLGIHD
LLLLRGDNSDRHNFVKPDEPGNKYAIDLIHQVNNLNKGQFLDGTFMEPFETPFSYGVAGY
PEKHEEAASLEEDILRLKQKADAGAEYIITQMFFDNSKFFDFVKKCREAGITIPIVPGLK
PINYLSQIKVLPDIFKTEFPEALTTELQKCTSNAEVAKVGTEWAAHQAKELMNHGFNLIH
FYTMMATNCVYDIAKKIY
>A0A6G7X2Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dysgonomonas sp. HDW5A|TrEMBL
MKVTDLIENNGKTAFSFEILPPLKGNSIQKAYNIIDKLIEFDPKYINITTHHSENIYKEM
PDGTVTKVNVRKRPGTVAIAASIQNKYNITAIPHMICKGFTKEETEYALIDLNFLGIHNL
LLLRGDAHKLESDQLAGNMNQYATDLQVQVNQFNEGITADGGTFDRFETPFSYGMACYPE
KHEEAPNLESDIHYLKMKQEQGAEYFVTQMFFDNSKYFSFVERCRAEGISIPIIPGVKPI
YKTNHLTLLPRTFRSDIPEELASELRKCQSDADAKEVGIEWGIKQCKELIQYGVPSIHFY
ALMATESVRRIAKEVY
>A0A6G2IEW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HUCO-GS316|TrEMBL
MGAAGLRALLDSVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLTTRLAAH
GYRVVPHVPARLLRDDAHLKEVVDRLREAGVDDVFVPAGDADPPAGAYDGALPVLRRLSE
LGGPFARVGVTGYPESHPLIHDDITIQAMWDKHEHATYIVSNLCFDARVLGEWIARIRRR
DVTLPVHVGVAGPVQRAKLVAMAAKIGVGESTRFLTRHASWFVRFAAPGGYAPERLLARA
EGTLTAPSAGVAGLHLFTFNQIAETERWRRALLERLGG
>A0A2E5ANV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
MKVTDYIKSAKQTLFSFEILPPLKGKSIQSIYDGIDPLMEFKPKFVNVTYHREEYIYKEK
GNGLLEKVAIRKRPGTVGICAAIMNKYKVDAIPHLICGGFSKEETENALIDLQFLGIDNV
LALRGDPIKTENIFKAHPKGHQFASDLIHQVNDMNHGKYCIDDIKMAPTDFCIGAAGYPE
KHFEAMNLKTDLIHLKEKVDAGATYIVTQMFFDNKKYFDFVEACREFGINVPIIPGLKPI
KTLNHITFLPKFFHIDYPEELSNELLKCKTNAEVEKVGIEWGIQQSKELIKQGVPCIHYY
TMSNSDAVKAIAGNIF
>B4CZD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacter flavus Ellin428|TrEMBL
MHIQDILARNKTSISLEFFPPRTPESSERLFQTIAELAPFAPSFASVTYGAGGATRELTH
DLVVRLRRTTALDPIPHLTCVGHTAEDIHAVLARYAAAGVSNLLALRGDLPQGSAASASS
FAQAADLVGAIRAFKHPHETRGFGIGVAGFPDGHPLTPNRLREMDHLKAKVDAGADYICT
QLFFDNHSFHDFRERCELGGIRAPILAGVMPVTTLSGLQRMAELAAGVRIPAKLLKRLAA
SGNDPHAVAEIGIQYAIEQCADLLRHGVSGIHLYTLNQSAASVRILRSLERP
>B7BAJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides johnsonii DSM 18315|TrEMBL
MKVIDLINSSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQKTDIYHEHATDLQQQVNNFNKGIAIDGSAFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDDEAKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVYKVAKEVY
>A0A1H0N4G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax cattleyae|TrEMBL
MSLSTHTAGLPVSFEFFPPKTPEGADKLRAVRQKLYALRPEFCSVTYGAGGSTQEGTFGT
VREILSEGVQAASHFSCIGATREGVRGQLAQLKAMGVSRLVALRGDLPSGYGAGGEFHYA
SDLVAFIRAEAGDDFHIEVAAYPEVHPQARSPEADLQAFATKVRAGAHSAITQYFFNADA
YWRFVDDVRALGLDVPVVPGIMPIMGSTQLMRFSDACGAEIPRWIRLRLQGFGDDAASIR
AFGLDVVTELCERLRAGGVPSLHFYTMNQSAATLEICRRLGL
>K1XRS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MHHKDKILSDIFKTGKKTLSFEVFPPKTAQGMENLIFHLKQLEKYSADYISVTYGAGGSS
QDKSLELLDAVHKNFERTVVAHFTCVGLDLNKIESFINRLSAMNIRNILALRGDPPKDST
NFDFNKNVFKYASDLVKFIKNKTNMCIGVAGYPEGHVQAPSKEADWDNLKFKIEQGANFV
ITQLFFDNSFYFRFKEGMLKRNIKVPLIPGILPVASIETLNKAVNLSGATITAKFKEIIN
KHTQPDDFKKASYEYVINQIRELQKDNVPGIHYYILNRSEVISEILENL
>S4GMI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis JCP8108|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIHSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKSGINVPIEAGVMPVVNANQVKRMTKMCSSKISEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A1V6DK06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium ADurb.Bin122|TrEMBL
MTYGAGGSTRERTAQVAHILKNEHGLTVMPHLTCVGHSRAELVDIAEKLYDDGFRNIMTL
RGDPPKGSTTFVPAADGLRYANELVTLLKQRHADFCLGVAGYPEKHPEAPDLATDIANLK
RKVDAGADFVTTQLFFDNDAYYRFVERCRAAGITVPIVPGIMPVLSLKQIQRITSMCGAT
LPATLTRRLEVAAENPAVVELIGVEWALTQIRDLYRQGAPGCHLYILNRTNSALALAAGL
AA
>A0A511Z7W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina luteola|TrEMBL
MNLLKRLQKEILVADGAMGTLLYSYGIDFCYEELNVEKPEVIEKIHQDYIAAGADVIQTN
TYGANALKLARYGMEKRVKEFNEAAIRIAKRAAAPGNQYVLGTIGGLRGIRKSDASLDEV
VTMVREQADALLSGDPDGLLLETYYDFEELSTVVKELRTLTDMPIIAQVSMDEPGILQNG
MQLNDALHQLETLGADIVGVNCRLGPYHTIQAFENVTLPNHAFLSAAPNASLLDVEDGRI
VYSSEADYFGRAATFLREEGVRLIGGCCGTTPMHIAAAKKHLKGLAPITKKTVTPQKPIV
IREAEPAKHEPLHIKAKTERTVIVELDTPRHLETDNYFEGANLLYEAGVDAITMADNSLA
SPRISNMAMGSMLKHEHNVRPLVHLTCRDHNLIGLQSHLMGLDALGVHDILAVTGDPTKV
GDFPGATSVYDVSSMELLQLIKQLNEGISFTGKSLRKKAKFSVAAAFNPNVRVLDRAVQR
LEKKIECGADYFITQPVYTKEKIIDIYEATKHLDTPIFIGIMPLTNIRNAEFMHHEVPGI
KLSEEVLGRMAACGDDREKATQEGIDIAKELIDTAAELFNGIYIITPFLRYDMSLELITH
IKELDEEKERKIVHA
>A0A147IK00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas yabuuchiae|TrEMBL
MTNTILTRAEAALAHEEPLFADVGGDIAVSFEFFPPKTEKMDAQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTMDAAAHLTCVEATREEIDQVAQEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPDSVDKQADIDNLK
RKIDAGATRAITQFFFSPEAYFRFRDAAAAAGITAEIVPGILPVSNVAQTRKFAAMCGAR
IPDWMDRLFEGLDDHPAARQLVAATISAEMCRRLYAGGVKGFHFYTLNRAELAYAISHLL
GVRGKKAEAVAAA
>M6FN82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira weilii str. 2006001855|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPDGDLKLMETVKELALLDPDFVTVTYGAGGSTRDK
TVQILSEISKRYSFPTVSHFTCVGANQDQIFKALEEIRSSEIVNLMALRGDPPKGEGKFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPDAKSLEEDVENLKRKVDAGTDFLVS
QLFFVNSIFENFLNLVRKAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A2T0ZYM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Antricoccus suffuscus|TrEMBL
MSEVSQFRTVRDALADGPTFSFEFFPPRDEESETQLWEALRRLEQLAPSFVSVTYGAGGT
TRSGTIRATERIAKQTTMLPMAHITGVDHSVDELRNLVGNLAAVGVRNILAVRGDPPGDP
EATWVKHPEGIEYAEELVTLVRDAGDFSVGVAAFPFKHPRSPDIDTDARYFVQKARAGAD
FAITQLFFDAEDYLRLRDRIAALDCDIPIIPGIMPVLSASTIERAPKLSGAPFPEKLGAQ
FAALHDDKAAVRELGIANATQLCQRLLDEGAPGIHFITMNRSKATLEIWDQLGIKRSPAR
L
>A0A2H1YHF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum piscium|TrEMBL
MKVTKHIEKANGKTLFSFEIIPPKKGNNIQDLYQNIEPLMEFKPPFIDVTTSREEHLYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFSKEETEYLLVDCHYLGIEN
VMALRGDAMSHQKYFERSKGGHQYATSLVNQIQNLNKGKYLHDVIEANHKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVKAAREMGITVPIIPGIK
PIAVKRHLQLLPQVFKIDLPQDLITEIELCKNNQQVREVGIAWAIAQSQELLKAGVPVLH
YYSMGKSDNIKAIANALF
>A0A437GYL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceicoccus ponticola|TrEMBL
MTQTPSVASALAGVPLFADLPGDVSVSFEFFPPKSEKMEAQLWDAVEKLAPLNPSFVSVT
YGAGGSTRERTHATVERIIREAHLPAAAHLTCVEASKAEIRAVAEQYWEAGVRHIVALRG
DPTTEGGTFVPHPDGYASAAELVAGLKEIAPFEISVAAYPETHPEATCPQADIDNLKRKI
DAGADRAITQFFFRPECFFEFRDKLATAGIDAPIVPGILPVSNVAQTRKFAAMCGSIIPD
WMDRLFEGLDERPAARKLVAATIAAEFCRTLYAGGVRDFHFYTLNRADLSYAICHLLGVR
PIGEKA
>A0A448PJU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces viscosus|TrEMBL
MIDNESAEPTESTAGVGSRGDDSGRGEPAAVRSARRSLPGSTGSLPTVSLELFPPRPGRA
ASATWGRIDRLLATGPDFVSVTYRPTFVTEPAPGPTERDRGADRLEPVGDRGDGMPRVRA
VQEETNPSEGVLAHVLESSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPP
AGTRADDVAGELRHADDLVRVIREVEADFFGDGRRHVTIAVAAYPATSDHIEAIEVLAAK
QAAGADLAITQVFYDPADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVKVP
EGLRSSLGSASGAALVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGG
ILAGAAPDREVRDAVDRGYLQATPGRGPSFLRCGSPGAAASSRHPVQPHTTITKENA
>A0A059DBQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eucalyptus grandis|TrEMBL
MKVIEKIRESAGVCNGGGNGGEGKVVFSFEFFPPKTEDGVDNLFERMDRMVVHNPTFCDI
TWGAGGSTADLTLDIANRMQNMVCVETMMHLTCTNMPVEKIDHALTTIKSNGIQNVLALR
GDPPHGQDKFVQVQGGFACALDLVKHIRAKYGDYFGITVAGYPEGHPDVIGQDGLATLQA
YQNELAYLKSKVDAGADLIITQLFYDTDIYLKFVNDCRQVGIHCPIVPGIMPINNYKGFI
RMTGFCKTKIPAEITAALEPIKDNEEAVRNYGIHLGTEMCKKILANGIKTLHLYTLNMEK
SALAILMNLGLIEESKVSRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTMGWDQYPR
GRWGDSRSAAYGTLTDYQFMRPRARDKKLHEEWVVPLNSIEDVHEKFKKFCLGKFRSSPW
SELDGLQPETRIINEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLE
LFCSPEKLNILVEKCKGFPNLTYMAVNKGGDKWISNVGDSDVNAVTWGVFPAKEIIQPTV
VDPASFLVWKDEAFEIWSRGWACLYPEGDPTQKLLQEIQSSYFLVSLVDNDYMKSDLFAV
FEDI
>A0A8J4C4Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Volvox reticuliferus|TrEMBL
MKIIHKINQKLKDGQTFFSFEFFPPRTEEGVENLFERLDRMATYGPIFCDITWGAGGSTA
DVTLDIATRMQNQVCVETMMHLTCTNMPVEKLESALKEVKKAGVHNILALRGDPPKGQDK
FEVVEGGFSCALDLVKYIRKEFGDFFGICVAGYPEAHPDGIVDDPEQMQKNYWADITYLK
QKVDAGGELIITQLFYDTEVFIKFVEDCRSVGITVPILPGIMPVMTYGGFKRMTGFCKTK
VPADILEAVEAIKDNDEAIKNFGIDLGVKMCRRLLEAGTPGVHMYTLNLERSAVAILERL
GFIDTSSVPKLLPWRHVPKGTARASESVRPVFWSHRPKAYLKRTQGWSSYPTGRWADRSA
LEYNTLSDAPQFMRRHTSTDARKEKARAAWGASLEGEQDVKAVFSKYIKGEVKLFPWSEM
EGPQHAESPAETTALLDLIAAGYLVINNQPRLNGVPSTDATYGWGAPGGALYGRAYVEIF
CSPAAWESLRPRLDAAASVSYLAATAAGSPQGNLKHDDVVALSWGVFPGKEIVQPTVLCP
ASFATWKDEAFELWLSEWAGLYEEGSASRQLLTGIHDRWLLVCVVDNDYVTGDLAKVLLG
>A0A146XG70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fundulus heteroclitus|TrEMBL
MVNQVQQVEGCWQSTKGESSGASNSSGESSKEGSRCSTPVLDADRSDRLQEKMRKRIASG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTREKITGYLAKAKHLGLKNIMALRGDPVGDDWEEEEGGFSYAI
DLVKHIRSEFDEYFDICVAGYPTGHPEAESYQQDLWHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIHQAVEMSRVLLDSGKVPGLHFYTLNREVATVEVLRQLGLWIEDPRRPLPWAVSANPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKET
LLQMWGEELKNEESVFEVFTCYIAAKPNRNGQKVMCLPWNDEPLAPETNFLKDELEKVNR
CGVLTINSQPNINGKPSTDPVVGWGPPGGYVFQKVLKYLFGHSQQRHSSLSC
>A0A149RF46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter malorum|TrEMBL
MSLSRLSVELIPRSEDALAQDVTSVKTLFPAADTLNIPDLMRFPLRSWDAAALTMPQFGT
VVPHVRAIDIAPGAPLPGSTLPGLKEVLVVHGDPPADLAHRTYPNSTESIIRRYRKEAPH
LRIYAAFDPYRRAPWRELEDIARKKDAGAEGFFTQPVFDLKLFDLCREWLQDEQVFWGLS
PVIGPRSRSYWETTNHVVFPKDFEPTLDANIQFAQSVLRQLSQDQGCAYLMPLRVKLDQY
LPPLMSALTA
>A0A5D2AZ51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium darwinii|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFDRMDRMVAHNPSFCDITWGAGGSTAH
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFIKFVNDCRQMGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQFPHGRWGDSRNPS
YGALTDHQFMRRRARDKKLQEEWATPLKSIDDIQEKFKSFCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSLSVGWGGPGGYVYQKAYLEFFLLKGKTRC
TCQ
>A0A7Y5TRZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
MGTMLYSKGVFINQCYDELNVRSPELVREVHRAYVKAGAEVIETNSFGANRIKLAQYGLE
GQVAELNRAAAGLAREAAGEKVLVAGAVGPLGVRLEPLGPTSLGEAREVFREQMQALKDG
GADLFVLETFSDLEEIEQAIRAAREVDPAMPVVAQMTIGVDGLTPYGATAADVARTLDEV
GADVIGLNCSVGPQTILEAVEKMTPVTRRKISAQPNAGMPREVGGRSMYMASPEYMASYA
RHLVQAGAKIVGGCCGTTPEHVHAMVEGIRPLSPRTAGARGQASGTAATAGAAGTATAGK
RVEPTPFAERSRFAAKIARGEFVKTVEIVPPRGTDATKLIADSTTLRNAGVDAINVPDGP
RAQSRMGAVLTSLLIEQRAGIEAVTHYCCRDRNLLGMLSDLLGASAMGLRNLLLITGDPP
KMGPYPDATAVFDIDSIGLTNLVRNLNHGLDPGGNAIGAPTCFAIGVGANPAAIDLAQEI
RRFEWKVDAGAEYAITQPVFDADQLERFLERIEHVRIPIIAGIWPLISVRNAEFLANEVP
GVSVPKAIIERMRKANEKSKEAALAEGIAIAREMLERVRPLVQGVQVSAPFGRVELALQV
TG
>A0A809YF04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium diazoefficiens|TrEMBL
MTDLTKPATADGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYGAGGST
RERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPPGGIG
TPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDAGAT
RAITQVFFDNDLYFRYLDRVRARGINIPVVPGIMPMHNFKQARAFVTRAGTSVPDWLAEK
FEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAKSAQ
KAA
>A0A356VK21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halieaceae bacterium|TrEMBL
MPTISFEYFPPKTADGKTALLERTTPALQALDPSFFSVTYGAGGSTRDSTFGVVSALCEQ
GIDVAPHLSFGGDGEDTIRDLLKRYRELGVRRLVALRGDMPSGMGGASQLVYASQLVSFI
REHSGDYFHIEVAAYPEIHPQAESYNSDLRFLKEKLDAGANSAITQYFYNVESYFYFLDQ
CAAIGIDKPIVAGIMPITNFANLARFSRNCGAEIPRWICQRIEGYGNDQESIRQFGVEVV
TQLCQTLLENGAPGLHFYTMNQVEPTRQIRNNLGL
>A0A199W252|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ananas comosus|TrEMBL
MKVIEKIRSAEEEGRTVFSFEFFPPKTDDGVENLFERMDRMVSHNPTFCDITWGAGGSTA
DLTLSIANRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVQHIRTQYGDYFGITVAGYPEAHPDVIQGEGGATLEAYSNDLAYLK
RKVDAGADLIVTQLFYDTDIFFKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
VPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKILANGIKTLHLYTLNMEKSALAILMNL
GLIEESRIVRSLPWRRPTNVYRAKEDVRPIFWANRPKSYIARTLGWDQYPQGRWGDSRNP
SYGALTDHQFMRPRSRDKKLQEEWAVPLKSIDDINERFMNYCLGKFKSSPWSELDGLQPE
TKIIDEHLGQINLNGFLTINSQPAVNGEKSESHTVGWGGAGGYVYQKAYVEFFCSAKKLC
SLVEKCKALPSITYIGVNKEGECVTNVGFSTVNAVTWGVFPAKEIIQPTVVDHASFMVWK
DEAFEIWTRGWACLFPEGDPSRELLEQVQRSYYLVCLVDNDYIHGDIFAVFKNL
>A0A5Y1PY05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A6V7EGZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. gardneri|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDT
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLIGR
>A0A3P9D4R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maylandia zebra|TrEMBL
MVNQVQRGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQSKEKITGYLAKAKHLGLKNIMALRGDPIGEDWEEEEDGFNYAID
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNY
GIQQAVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LKMWGEELQNEESVFEVFTCYITAQPNRCGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVNGRNLTNAPEMQPNAVTWGIFAGREIVQPTVVDPVSFMYWKDEAFALWIEQWGK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPELHSEETV
>A0A7V4KFH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium pennivorans|TrEMBL
MGGINKSTFFDYRFILETLPPRGTNPDKYLSFCKEAVEHGAQIIAVTDLPMGSARVSPIA
PAHMLVEMGLEVLMHFSRTTRNAIRIEGDLIAAHMLGIKNLLILSGDDPRVGTYPFSSSI
EDFSIYDVFKLTKLLNEKGEDLAGLKIFGSFSFNAGGVFSPFEKDLNQTLERMELKMQNG
CQFFVSQPVFNSETILKLFEKSETEELFKRTKIYIALMVFESFQQLEHYSKVPGVFVPKE
YFWQKDDTHLEQYSINQCISIIEKLAPYVHGFYLTSTTKKMETIKTISDAVVSQY
>A0A3S5JRQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium TMED42|TrEMBL
MKVTDHQKNAKGRTQFTFEILPPLKGQDIQSIFDSIDPLMEFKPPFIDVTYHREEYTYVE
RENGLLEKRVIRKRPGTVGICAAIQNRYHVDAIPHILCGGFSQEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPSKGGHAYAKDLVVQIKNLNQGQYLDEEILNSSPTDFCVGVAGY
PEKHAEAPSLDNDIHFLKEKIKAGSDYIITQMFFDNQKFFEFETKCREAGINVPIIPGLK
PLATLKQLNLIPQRFHVDLPKDLIDAVVKAKDNTAVSEIGVEWCIQQSKELKQHGVPFLH
YYSMGKSKNVKKIASALF
>A0A6I0EDV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MRIREQIDEHGPTVSFEFFPPRDEVGFWDLYRTVEALRPLTPDFVSVTYGAGGGTRRKTL
DLVARIKSDIGLEPMAHMTCVGASRNEIAGILDELVIKGVENVLALRGDPPEGTSAFTPV
PGGFRYANELVTFIRERYRFCVGAACYPEGHTEAPTLDIDLENLKRKVDAGVHFLISQLF
FDNDAFYRFRDRAERAGIHVPILAGIMPILSVKQVKRFTQMCGAAIPRDLLHRIESVEDD
NEAVRHVGMFHATQQCLGLLACGVAGIHFYTLNRSTATRAIYQYVRGELPKRRASRSDSG
PH
>A0A6V7BJT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. gardneri|TrEMBL
MYHPITTKARQKILIYPDTPSLASTVTDAYSLEVSATDIPGLTAAAPRIMRGSTIAIPYL
PSQDNDARLAAAQSVRALGFAPMPHLSARRITSLEELHAFVRRAVDDAGVERCLVIAGDA
PSAIGPFPDSVSLITTGVFERAGIKTIGVAGHPEGHPGMPATDQWDVLERKCRSIAERGM
APLIVTQFAFDADIVLTWLEALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACASML
SKYGISIGKLFGSAGPDCFVDRLATGLTEAHGDVSLHFFPFGGIAQSVAWVEQYRSRTAA
HIL
>A0A532DJS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPRRLREVLDQGQFAVTVEYNPPKGTNISGVLENAKQLVGRVHGVNVTDNTAAVVRA
GSLSVCRLLYELGHDPVMQMTCRDRNRIAMQSDLMGASMLGIQNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGRDMAGNKLDGTTAFTIGAAVTPEADPLGPMLAKFEVKV
KAGAQFFQTQAIYHPEQFASFMKAVRPFKAKVLAGILVLRNAKMAEFMNANIPGVSVPQE
MIDELRAAGPERAEDVGVDIAVRTIKAVRPYCDGVHIMAIKATHRLADIITKAEVG
>A0A349EJV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MKSGSNLEKVLASGKPAVTAELGPPMSADPHEVVHKAKQLKGFCDAANITDCQTAVVRIS
SIAAAAIAFQNGLEPVMQMTCRDRNRIAIQADLLGAAALGLKNCLCLAGDHQKFSAAGRL
KGHPGAKNVYDLDTSQLVSMLKKMRDESKQEGGDPIEVPPKFFIGASWTPMGDPIDIRPM
NLLKKVNAGADFIQTQGIYDMELFRAQMAKIRDLGLHERTAILAGIIVPKSAMMLKYMDS
SVAGVSVPKAMIDRMSKAKAAAGEDKKKMKELQEQEGIKITIELIHQALETPGVKGVHIQ
AIEWESAIEGIVKAAGLYPRPSF
>A0A4S9PJN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MDRVHLFIFFILFFIAKRLISRHRQVNRRAAAKEKKATYSFEFFPPKTAQGVQNLYDRMD
RMHNFGPSFIDITWGAGGRHASLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEA
HDAGCTNILALRGDPPREKEKWEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDD
NDNPEELIQHLKEKVDLGGTFIVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHA
AFLRRANWSNIHVPPHWHEALEPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMN
LAQSTRMILEELSITPSQDTPLEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDW
DEFPNGRWGDSRSPAYGELDTYGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVES
LPWSESPITDEADALRKDLINLNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAY
LEVLVSPELISELITRMERNPNITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPT
IVETVSFLAWRDEFYRLGSDWSRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFP
LFDELEVPDLNKEVTAPEAPQKVNGATNGEKHEEEPKVGNGDVTDSKIPDSVHKKLETQI
NGAEEKPDTEPKDATAHNTGAGPSTSV
>A0A2E9RFI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp|TrEMBL
MSKRISFEFFPPKTEQGREKLLNTQKKLLVKKPEFFSCTFGAGGSTRDYTRQMVDLLREQ
HADTAPHLSCIGQSRDEIMELVNGYKEKGVTRIVALRGDLPSGMGYAQSEVKYADDLVAL
IRAETGDHFTLEVAAYPENHPQSRSFDDDIEHFKRKIDAGADSGITQYFYNADAYGYYMD
ELRRRGCDAPVYPGIMPILNVANLFRFSDNCGADIPRWLRGRLDDIRDDETAVKAFGEEV
VTRLCERLLAMGAPGLHFYTMNQAAPILRILDNLGL
>A0A6B5TC62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIHEGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A4R0VHR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A5M3YDT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus aetherivorans|TrEMBL
MTFDSDSGPDGGGESRTPSVVDRLRAPRGARIPFSVEFSPPRDADAEARLWRAVREFERL
GPAFVSMTYGAGGSTRDRTVRVTGQLAQETTLLPVAHLTAVGHSIDELRAMVGAYADRGI
TNILALRGDPPGNPLGEWTRHPEGLEYAEELVRLVRDLGDFHVGVASFPEGHHRSPDLEH
DTRYLVHKLRAGAEYSITQMFFDVEDYLRLRDRVVAYDPEQGAKPIIPEIMPITSLRTAR
RSLELSGSRLPAALEERLVRAAGNGPEEDRAAVREVGIDVATEMAERLIAEGAPCLHFIT
LNFARATREVLARLGIAVPTAV
>A0A2S1YVL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces spongiicola|TrEMBL
MALGTASTRTDRARTVREMLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAARPSFVSV
TYGAGGSTRAGTVKATQQIAADTTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPDGVRYAAELVRLIKESGDFCVGVAAFPEMHPRSSDREADIGHFVD
KCRAGADYAITQMFFHVEDYLRLRDSVAEAGCETPIIPEIMPVTSVKQIERFARLSNASF
PAALEARIRAVADDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIHENLG
LHQQS
>A0A4S9Y4S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVNVTWGAGG
STSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILALRGDPPRS
DEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQSHPEHQHA
TYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGLMPIQSYQ
ILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSGPKGFHFY
TLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSIANSAPQNRVV
IDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIPWSEEGLN
PETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVEFFCSHED
WTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIEAVSFRAW
AEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLLEA
>A0A3E4WE08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola plebeius|TrEMBL
MKVIDLIKNSKEPVFSFEILPPLKGNSIQKVYHIIDKLREFDPKYINITSHHSEIVYLPQ
PDGNLKKTTVRKRPGTVAIAAAIQNKYGIQAAPHIICKGFTKEETEYALLDLNFLGINNL
LLLRGDSKPLDIAEKDLCLYHEHATDLQEQVNRFNQGIGLDGSKIEGIETPFSYGMACYP
EKHEEAPNMESDLFYLKEKVRNGADYVVTQMFFDNEKYYAFVERCRQEGIDVPIIPGIKP
VVFKNQLNVLPKVFRTDIPEAFASELRKCTTDEEVKAVGVEWCKAQCKDLLAHGVPGLHF
YTFMASDSVYKVAKEVY
>A0A2V8FJE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MLKPFIEALDDRVLVCDGAMGTMLYAKGVFINKSFDALNVTQPDLVAEVHQEYVRAGADI
VETNTFGANRIKLGSFGLAERLYAINAQGAKIARHAALEHAYVAGAIGPLGIRIEPWGKT
GLDEAREFFREQAHALVEGGVDLFILETFRDLNEIGAAIDAVRSVSGLPIVAQMTTEEDG
NTLDGTPPERFTPDLERRGATVIGVNCAVGPAPMLDTIERMAAVTKRRLSAQPNAGQPRD
VEGRNIYLCSPEYMASYARRFIMHNVRVVGGCCGTTPEHIRQIKAAVRGMAPAVGRAADT
GAGTRPMPAISAPPVAREHKSRLANAVARGSFVVAVELLPPRGYQTDQVVEWAKRLSISG
VDVVNIPDGQRAGARISALSLAVLIQQQAGIETLLHYSCRDRNLLGIQSDLLGAHAMGLR
NLMLVTGDPGRVGDYPDATAVFDVDSIGLTNLVSRLNHGCDVGGQAIGAPTGFHIGVSVN
PAASNLDEELRRFEYKVEAGAEFVVTRPIFDVRGFERFLKRVETARLPIIAGVFPFESSR
NAEFMANEVPGVQVPDSLLDRMARADGHEAATQEGIAIARQIAAELRGAVQGVQVSTQSG
DIEAALAVLDGLR
>A0A8H3ZFC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Venturia inaequalis|TrEMBL
MFISSRLEEAEKAKKPTFSFEFFPPKTAQGIQNLYDRMDRMHGYGPTYIDITWGAGGRSA
HLTCEMVKTAQTALGLETCMHLTCTDMPVSKVDEALKEAHDSGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVTYIRKHYGDHFDIGVAGYSERCEDNEDVDQLVDHLKEKIDAGATF
IVTQMFYDVDLFLDWVRKCREKGITVPIVPGIMPISTYAAFIRRANGPMRCHIPKAWLEA
MEPIKNDDAEVREVGMRLVTELCQKLLASGEIHHLHFYTMNLEKATRMIIENLGLMPDVG
SPVEKPLPWRQSLGLKRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFGEL
DAYGIGLKGSNEHYQKLWGEPQTIKDISNLFVKYVQGKLESLPWSEQPISQEANSITDDL
IDLNRRGILTINSQPAVDGVKSSDPTHGWGPRGGYVYQKAYLEVLVSPELIAEVITKIER
DDDMTYYAVNKHGDLKTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEFFHLGQ
DWAECHPSSSASRHLIENVMENWYLVNIVHNDFHETHGVFHLFDDLKVEDVDKPFANPKD
LPIREKTNGLSNGLETAAMNGASAITV
>A0A8D0HXW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKH
IRSEFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLK
ACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GQELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMLIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>F1RF82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKH
IRSEFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLK
ACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GQELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMLIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>A0A165NAA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHADHPVYILGTIGGLAGDTDATVQR
ATPATIAASVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFVGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A2V6L7W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRGEYPTFSFEFFPPKTPEAAETLYQTIRDLESYMPDFVSVTYGAGGSTRELTH
DLVERIQHTTKLNPIPHLTCVCHNEEEIQAILRRYAKSAIGNILALGGDRPAEMSYDKSR
DSFQHAIDLVKFVRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHFKAKVDAGA
DYIVTQLFFDNHDFLDFRERCALAGVHIPIIAGIMPITSIGGLKRMAELAGGARFPAKLL
RALQSCQDNPEMVRRVGIQYALEQCHDLTANDVAGVHFYTLNRSDATRTIFDGLSIPRHR
NLQPSRV
>A0A0F2D3W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A397YMC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica campestris|TrEMBL
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNAICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAYGIHFATEMCKKILAHGITTLHIYTLNVDKSAIGILMNL
GLIDESKITRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYSTLSDYQFMRPRARDKKLQQEWVVPLKGIEDVQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TLVEKSKAFSSITFMAVNKAENWVSNIGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKSSYYLVSLVDNDYINGDIFSVFA
>A0A2E7LNV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MHNLVESYTSADTPLVICDYSPPRSPRQLNVESIEKLPIDYFSVAYNPGRSPRVDSITVA
RSLQEKTGKPAIFTIATRDMNKIAIQSQLLGAYMAGLSHVLLLGGDSLSQEELALGATEV
RNYKPTELIASTAELSAGWDYRGKPIQPPPTFCIGAALDTTRDLTKEVLLAEKKIEAGAN
FFISQPIYEITEYQNFLTAYRKITGKELSVPVFWGLQMLTSDGPIFGNPPKAFLRDLEEG
ISSEVIAKKQFAEMKTAGIKGVYLIPPISANGRRSYSSITLLLDN
>A0A3P5Y6S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica campestris|TrEMBL
MKVVDKIKSATEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNAICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGEDK
FVQVEGGFACALDLVNHVRSKYGDYFGITVAGYPEAHPDVIEADGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAFGIHFATEMCKKILAHGITTLHIYTLNMDKSAIGILMNL
GLIDESKITRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYGTLSDYQFMRPRARDKKLQQEWVVPLKGTEDVQEKFKELCLGSLKSSPWSELDGLQPE
TKIINEKLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSRDKLD
TIVEKSKAFPSITYIAVNKAGNWVSNVGEADVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYFLVSLVDNDYINGDIFSVFA
>A0A1V2JKJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas azotoformans|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISTMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A6P8WW79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gymnodraco acuticeps|TrEMBL
MVQRGDSCKSDFSGASNSGGESSKESSRCSTPVLDADRLDRLRDKMRKRTESGDCWFSLE
FFPPRTAIGAVNLISRFDRMGTGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLD
SILHLTCCNQTKENITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNHAIDLVKHIR
SEFEDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVITQLFFRADTFLKFLDDC
RAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITEVIEPIKDNDAAIRNYGIQQAV
EMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVR
PIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALQQMWGE
ELKNEESVYEVFTCYITAQENQSGHKVKCLPWNDEPLAPETNLLKDELEKVNRRGVLTIN
SQPNINGKPSTDPVAGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNV
HGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWANLYEEES
PSRMIIKYIHDNYFLVNLVDNDFPLESCLWQVIDDMFELLDAPPETHHDGEVSE
>A0A7C8PVT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orbilia oligospora|TrEMBL
MHIKDKIAACEKAGKPCFSFEYYVPKTAQGVQNLYDRMERMGSFGPQFIDITWNAGGRLS
NLTTEMVNVAQTVYGLETCMHLTCTGMEKEKVDNALQEAYNGGCTNILALRGDPPRENEK
WSAVPGGFRYAKDLVKHIREKYGDYFDIGVAGYPEGCDDEVDPDILLDHLKEKIDAGGTF
IITQMFYDVDIFLDWVNKVRAKGITVPIIPGIMPIHTYAAFIRRATWTKIHVPEKWLEVL
EPVKNDDVAVRDIGRDLVVELCKKILAAGINQLHFYTMNLATATRMVLEGLDLMPSLEAR
ELPALPFKSSLGLGRREENVRPIFWKNRHKSYVARTQEWDEFPNGRWGDSRSPAFGELDT
YGIALKGTTEQNIKLWGRPETVAEIADLFVRYIDGKLETIPWSDSPIDASAEPIKAQLSE
LNKRGFLTTNSQCALNAVKSSHPIHGWGPKNGYVYQKMYVELLVSPDVLSELITRIERSP
DLTYYAVNKAGVLHHNAPAGGSPNAVTWGVFPGKEIVQPTIVELISFLAWKDELYRLGED
WAACYPQSSASRHIISSVMENWFLVNIVNNNFLDNDSIFELFKDLKIDNLNEKIPVDEYL
QNLKITDGSNGTAHEATNGAPAA
>K9IVF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MDRPKAKGLPAGQCCPSLGVRALEAGISRSSVPPAISRSSAMVNEPRGNGGPGPRCEGSS
SGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEVTG
YLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACSEMGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMLIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>A0A7C0W835|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSFKDALNSGRFVVTAEAGPPKGTDISKIVHEVEALKGKVDAVNVTDNQSAVMRISSTSF
CKILIDMGIEPILQMTCRDRNRIGLQSDLLGASILGIRNVLCMTGDHPNAGDHKEAKPVY
DIESVQLLGVIDALNNGKDMMGNDLQGSTDYLQGAVVTPEANPLEPQLMKFKKKVNVGAK
FFQTQAVYNIDNFKSFMGHARKYPVHPVRKDAGYNGVKILAGLVLLKSAGMANFMNKFVP
GIIVPQELIDELKAAGKEKALDTGIDIMASHIKQLKAENVCDGVHIMAIGAEDKVPAIME
RAGLL
>A0A106DKS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia anthina|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAVATRTICERLAV
>A0A2K3JWH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trifolium pratense|TrEMBL
MKVIDKIRSAAADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANKMQNIICVETMMHLTCTNMPVDKIDHALETIKSNGIQNVLALRGDPPHGQE
KFVQTEGGFACARDLVWMFLTLE
>I4KDW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas lactis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMTTAKQLASFSPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3B9B3N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp|TrEMBL
MEAPLFSGLPGDIEVSFEFFPPKSDKMGETLWQSVETLAPLGPRFASVTYGAGGSTRERT
HQQVVRIQNEAGIPAAAHLTCVEATREQVDDVARHYWEEGIRHIVALRGDPPDGQSRYSA
HPGGYANAAELIAGLKKVADFEISVAAYPEVHPDSSDRKADLDNLKAKFDAGATRAITQF
FFEPECFFDFRDQAAAAGIKGEIVPGIMPVMSFAAVQRMSGLCGTAIPHWMEGLFEGLDE
RPEARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKA
>A0A858NBH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster clostridioformis|TrEMBL
MKIREILAEGKPTLSFEVFPPKTEDAYDSVEKAAAKIAKLKPSFMSVTYGAGGGTSDYTV
GIASAIKEEYAVTPLAHLTCVSSTREKVHHVLGELKERGIENVLALRGDIPQDGSTPKEY
HYASELIREIKKAGDFCIGAACYPEGHVESANKSVDMDYLKQKVEAGCDFVTTQMFFDNS
ILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTCLPSRFMSIVDRFGDNPAAM
KQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A5P0W6U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLHQQGDKRGFSFEILPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHTHATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDEDAKQLGIEWTTAQVQDLFEHGYKNVH
FFTVSAVDSVKQIAKILF
>A0A8F9IAU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O139:H1|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7J9TQ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|ANME-2 cluster archaeon|TrEMBL
MGFADVLESGKFIVTAEVSPPKGTDISGALAGAGLLQGLVDAVNVTDNQRSMMRMSPIVL
CHKLGELGFETIMHMTCRDRNRLALQSDLLAAHALGVHNILAMSGDYPTMGDQPSTKPVF
DLDSVQLLQLIEKMNKGFDFQDKPIDSPTSLYTGAVANPGARPLGPQLLKLNKKVSAKVR
FIQTQAVFDASVFNEFADAARHTGIPVIAGIIPLRSVQSARFMNEMIPGVNIPDEAISRM
EAAEDPALEGIRIAAKTIADIRTNCQGIHIMPIGGHGNTRRLLEMCGLD
>A0A2K9B125|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium breve|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQAVGEFNHASDLV
SYIRSVKPDLKVFGACYPEGHYQADTIDQDIENLKIKVDAGATHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRAAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A3A4N409|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pseudopneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKSILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A6L4WYV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium ramosum|TrEMBL
MHSPMFSLEVFPPKRDAPIGTIYDALDGLEGLKPDFISVTYGHGTHADRTATARIANTIR
KDYQIPTVAHLTALYSDKSRIDEALDLFEDAKVGGVLALRGDHLDGCEPVGVFNHANDLI
AYIHERRPDLKIFAACYPEGHIESDSLDDDIAHLKLKVDAGASHLISQLFYDNADFYRFL
DKAHAAGIDVPIEAGIMPVTSAKSVYSMAAKNRTRIPKAVAAMLDKWGDDLPSLRAAGIN
FAAQQITNLVANDVDGIHLYTMNRAATARRIWHNVEPLFAR
>A0A6V7FD89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. carotae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDT
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A0C4USH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria laubenfelsii|TrEMBL
AYGIHLGTEMCKKILAHGIKTVHLYTLNLEKSALAILANLGLIDMTKIKRPLPWRPPANV
>A0A412Z2F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster bolteae|TrEMBL
MKTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTRDDVLLILEQLKEQKIENILALRGDRTADREPAGDF
RYAADLVEFIKNHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFRERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFISMMERYGDNPIAM
RDAGIAYAVDQIVDLAAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>G7K531|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Medicago truncatula|TrEMBL
MPVDKIDHALETIKSNEIQNVLALRGDPPHGQEKFVQTGGGFACARDLDAKSVSKPATVA
KKSMKDSSDSDDEDDDTSSEEEKKPVAAKKEDKMNADKDSSDSDESEDEPSKRPQKKTSS
GDNGKPNICNNWSGSILGLEVLAQLANDEIARPDVVIRVRTRDLTIESIGFIFSICSVSS
LLGAILCQYALKDYAFRDLLFWTQLLYGLSGMFDLILVMRLNLKFGILDYIFVVIVESIA
SKLCPSGIEGTFFALLMSIDNARILSS
>A0A2A7A3S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MLDVRKLLAQRPLLFDGGMGTYYKAKPGQECEQANLTDPEGILAVHRAYLAAGADAIKTN
TFSLPRLAAAQQPGWEQLADAGWQLAVKAAGETGAAVFADLGPAPDTENLPAEQVYLAVA
KRFALLGARNFLFETLSAEDGVLEAIRALKQTVPEAFVLVSFAVLPDGYTREGRYCAELV
RRVAQSGVVDAVGLNCVSAPGAMRALVQQLGDAGLPLSVMPNAGYPVVARAQVRYQGKPE
YFARELSRLASEGVRILGGCCGTTPQHIAALRTALDALPEVLPAAPAAKPAVAAKPAVET
DDAFLRKLRAGQRVIAVELDSPKDADLTAYLEGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGMNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPITVFGALNLNARNFEVELRRAAEKLENGMSGFL
TQPVLSAQAVENLKKTRETLGERAKILAGILPVVSQRNAIFMENEVNGIHVDDAIIQRFE
GLDRAAGEELGLEVSVQAAKAAAPYVDGFYLMTPFNRVALMERLIARLRTEVTG
>A0A6C7HUV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enteritidis PT4 (strain P125109)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A725VFT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enteritidis PT4 (strain P125109)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3M5YN48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. tomato|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A174J0Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor plautii|TrEMBL
MMDIRTYLSQGKPLLFDGAMGTYFAAHPGRAEERCERANLTRPEEILRIHRAYLQAGCRA
IKTNTFAISGDLSDGNDETACDIVNAACHLARQAAQPYGAYVFADLGPAPRDHSRAPADL
YQTQAQWFLEQGVTHFLVETLSGDEGLPELAGWLKEKNPDAFLMVSFAVDHSGMTSAGRL
GSELYRFASELAGVDAVGFNCVSGPRHLLKYIQTLELSDKPLTVMPNAGYPTVLGRRTVF
GGQPDYFAGQIAQIVQAGASIVGGCCGTTPEHIAQTAQALKEPLPKCTVSAPKKLLKPAA
NASNSLWEKLEAGKRVIAVELDPPVDDDSAGFWEGVQALRGSGADAVTIADCPIGRPRAD
SSLLACKIKRDIGIEPLPHMTCRDRNLNATKALLLGLSMEGVHNVLVVTGDPIPTEDRNE
VKSVFNFNSRKLARFVHMLNENTLRTPFRIYGALNLNARNFDVELRRAQEKEACGVSGFL
TQPVLSAEALDNLKLAHKTLRGKILGGIFPVVSHRNACFLNNEISGMRVCDEIIHLYEGK
DRDAAEALAVTVSTAIAKEIFPYTDGYYLMTPFRRVALMEHIIQNIQQSCIS
>A0A0B7H5K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga canimorsus|TrEMBL
MKITEHIAKAKGQTLFSFEIVPPKKGNNIEELYQNIEPLIEFKPPFIDVTTSREEYFYKE
HPNGLLEKKITRMRPGTVGICSAIKYKYGIDTVPHVLCGGFTKEETEYLLVDCFYLGINN
VMALRGDAMKEERYFQPTKNGHTYAAQLVKQIKDLSKGKYLHDVIETDYGADFCIGVAGY
PEKHLEAPSLSFDLARLKEKVDAGADYIVTQMFFDNQKYFDFVERVRLAGIDVPIIPGIK
PITNKRHINLLPQVFKLDLPEILVTELEKCKTNKEVKQVGIEWAIEQSKELKNYGVPTLH
YYSMGKSDGIVDIVSKVF
>A0A351BI26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter sp|TrEMBL
MTTTAPTFSLELFPPQTPEGADKLRAARAEMALLHPRFFSVTFGAGGSTRDRTLETVLEI
QQEGHQAAPHLSCIGSTRASIRSILAQYRTHGIRHLVALRGDLPSGMARPGSFRYANELV
QFIRSETGSWFHIEVAAYPEYHPQARTPLDDLLAFQRKIDAGADSAITQYFYNFDAYAHF
IDECQAVGINVPIVPGIMPISSFSSLARFSDNCGAEIPRWIRKRLESYGDDRASIQAFGL
DVVTQLCERLLAAGAPGLHFYTLNQVGLTRTLWQRLGLTSPVEA
>A0A0B8PM68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio ishigakensis|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLVAAPHLTCIDASRDELINIADDYWNNGIKSIVALRGD
IPPGGGKPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRSVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMSQQFE
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQTA
>A0A123VV55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINKNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A064BZJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPYFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A5C4WTI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea phyllanthi|TrEMBL
MSISMLARRPATVKEALASGRPTISFEFFPPKDGAATGRFWECVREIEAVRPSFVSITYG
AGGSTRDRTIDVVAAVARTATMIPVAHLTAVGHSVADLRLILERYREAGVRDVLALRGDP
PGDPQAEWVPHPRGVAHAVDLVRLIREHGDFTVGVAAFPEKHPRSPDWESEIRHFVDKCR
AGADYAITQMFFDVEDYLRLRDRVAAAGCDVKIIPEIMPVTDAAQIERFAALSGATLPEP
LASRVRSAGDPAAVRAIGVEHATMMGARLLAEGAPGLHFITLNRAGVVLDIHRALGLPAA
RP
>A0A0B7L6J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A820S3X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MEFTLGDNQTVPGDCKMHAHETHLESIHNLNRVKRIESEGANIAGKICSLQSAKYVSLTE
KISKRIADNDRWFSLEFFPPRTPSGAANLIGCFDRMAAGRPLFCDITWHPAGDPAGDKET
SSMMIANTMLNYCGIDTMLHITCYGAKKAAMLEYLYKAKDCGIRSLLALRGDPHVGEEWN
PAKSDFRYALDLVKFIRQHFGDYFVICVAGYPQGHPDSTSYEDDLDYLKEKIDCGADFII
TQLFFQAETFIKFESDCRSIGIKCPIIPGILPIQGYASLRNIVRLAKLDVPKEILACIEP
IKDNDEAIRNFGVQACLDLCCALLDSGKVNGLHFYTLNREFATIEILKKLGLWLDEQSLR
ALPWKKTSFSHARSQENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGISSAPSFGVLTDYH
LFYMKIDATRDELLDEWGRELTCEQDVWKMFACYIGGEKNSIDKVVRRFPWTDEELSAET
TLIQKNLVEFNKRGILTINSQPAVNGKSSSDPVVGWGTPNGYVYQKAYLEFFTSAENIPA
LRSVLKTFPGVNYHFVNKSGEANETNTDDEQPIAVTWGVFAGKEIVQPTVVDPVSFMIWK
DEAFSLWTERWGKLYEPESRSHAIIEKIANTYFLVNLVDNDYPQGSCLWTILDSMFEYQK
LPKKNVES
>A0A421IJ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATGDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A818BRF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MEFTLGDNQTVPGDCKMHAHETHLESIHNLNRLKRIESEGANIAGKICSLQSAKYVSLTE
KISKRIADNDRWFSLEFFPPRTPSGAANLIGCFDRMAAGRPLFCDITWHPAGDPAGDKET
SSMMIANTMLNYCGIDTMLHITCYGAKKAAMLEYLYKAKDCGIRSLLALRGDPHVGEEWN
PAKSDFRYALDLVKFIRQHFGDYFVICVAGYPQGHPDSTSYEDDLDYLKEKIDCGADFII
TQLFFQAETFIKFESDCRSIGIKCPIIPGILPIQGYASLRNIVRLAKLDIPKEILACIEP
IKDNDEAIRNFGVQACLDLCCALLDSGKVNGLHFYTLNREFATIEILKKLGLWLDEQSLR
ALPWKKTSFSHARSQENVRPIFWSIRPKSYVHRTSSWNEFPNGRWGISSAPSFGVLTDYH
LFYMKIDATRDELLDEWGRELTCEQDVWKMFACYIGGEKNSIDKVVRRFPWTDEELSAET
TLIQKNLVEFNKRGILTINSQPAVNGKSSSDPVVGWGTPNGYVYQKAYLEFFTSAENIPA
LRSVLKTFPGVNYHFVNKSGEANETNTDDEQPIAVTWGVFAGKEIVQPTVVDPVSFMIWK
DEAFSLWTERWGKLYEPESRSHAIIEKIANTYFLVNLVDNDYPQGSCLWTILDSMFEYQK
LPKKNVES
>A0A0Z8YAI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVQSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARTIHQATHSLFKHYS
>A0A534FLY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNAESGRTPIRVSFEFFPPADEAMGAMLWKSIERLAPLAPRFVSVTYGADGSTRERTHNV
VTRIQRETPLTGAPHLTCIGASREEILEIARGYWDEGIRHMVALRGDPPQGEGARRPNPR
GFRYASELVAALAGLAPFDISVAAYPEVHPEARSAAADLENLKRKIDAGATRAITQFFFD
TDAFLRFRDALAAAGVHAPIVPGILPITRFPQVLRFAKACGTSIPGRLHERFAGLDDDHE
TRRMIAASVAIEQVEVLRRHGVSEFHFYTLNRAELTYAICHALGLRPHARSASAGLQEAR
A
>A0A511FBF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas hominis|TrEMBL
MSSTGARVPAEGAAPATDHVTDGLGAVDRPTVSFELFPPRNPEAAPRLWTTVERLAAARP
DFVSVTYGASGSTRSTTRALVRRLLRETSLTPIAHLTCVATSRDDLARTVEEFLDEGVRA
FLALRGDPPADGSWAPHPDGLPTASALVALLREVEARRCASSPAQAVRAATRPLSVAVAA
FPRGNAGSGSTREQDVAALLSKQRAGADFAITQVFYDVESYCELVTLARDAGVTIPIVPG
IIPMTDPSRLRRVQQLTGVPVPQAVLDVLDAFDPDDPADAARRLRAGTRLGVDLVNGVLD
GGAPGVHLYTFNQHGPALDLLEGAGLGGDAPRTHSQVTSAPTTTPTPVPTS
>A0A1X7CSF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria indica|TrEMBL
MPAPLAASEPAPVTGPPTGTSWLVRRPRRSTLVSFEVFPPRPTADPDTVWRNIDAMAQAG
PDFFSVTHGHAGHHGVSREALRHLRRTTKTPVMAHFTCGGTDRAGLERAVDQLLDDGVRD
LLALRGDPPLGTGEWRTPAGGLGRASQLVELIRDVERRRFGTGFRPGQRPLSVSVACYPS
PARGRDFEADLASLWDKQEAGADYAITQVLYEPEDYATFLERARSEGIHIPVVAGLMPLS
NPQRLQRMTEITGVRVPERLTRFLRADTPEELRHRGVAATLSLIDDLMDLGCAGFHLYTF
NRPEAALTILEHLRVRDAAREYRGRSPAA
>A0A2E6LXA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSNTSNHKPSISFEFFPAKSEESQNKLREERTKLAAADPTYFSVTYGAGGTTRSHTLETV
LETRKVTGINSAPHLSCVGDNREHLGSLLEEYKSHGINKMVALRGDLPSGMGILKGEFAY
ARDLVAFIREKTGDHFHLAVAAYPEMHPQGVTMDLDFQRFVEKVDAGANSAITQYFYNAD
AYEHFMDLCAKKNVKIPVVPGIMPITNYSRLARFSQMCGAEIPRWLEKQLMAYGDDTKSI
RQLGEEAVTRLVEKLIGLGAPSFHFYTLNQAEPSLAICRNLKLGAFD
>A0A5J0QJU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Kottbus|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A562PN72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia flava|TrEMBL
MADHNFSIEFFPPKTAEGAEKLRVTRAKLSELHPKYFSVTFGAGGTTQQGTLDTVLEILA
AGEQAAPHLSCVGGTRESIRAILAQYKSHGIRRLVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQAKSPQADLDAFVRKVNAGANAAITQYFYNADAYFQFVD
SATKAGVTVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQAAATTALWQRLVK
>A0A0C5BTY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter toxicus|TrEMBL
MTSTRYEIIPSDDTVERVQRVFADPSVVTLTVASLPKHGTEHTIACAMELAGRGFRVVPH
LAARAIESRWALKRILSRLCDAGIDEAFVVSGDAQNPAGIYSTGLELIRDAVEFSPELAL
DIAGYPEGHPHLSDESMWHHLRERAPFVRAVVTQLCFDVDAVARYADSLREQGITAHVVA
GVPGPVKKTRLLNVATKIGVGPSLNLLQRSSSATDDASDRFDSMAFIARLTATAAGRIAG
HHIYTFNDLDALAATLR
>A0A484PBW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|plant metagenome|TrEMBL
MEVSAKDIPALTAVAPRLPPASTISIPYLAGEGNAARLAAARAVRELGFEPMPHISARRV
ASLSELQAFVARAAAEAGVERCFVIAGDPSTPKGPFPDSFSLIDTGVFERAGIKALGVGG
HPEGHPVMSVADRWEVLERKCRGIEGRGMAPSIVTQFVFDADVVLTWLEALRARGIAHPV
RVGVPGPAGVAVLARYAAMCGVGACASMLAKYGISIGKLLGTAGPDRFVDRLAAGLTPAH
GTVSLHFFPFGGIAQSVGWIEQYRATRKQNTR
>A0A354L858|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHTHATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDEDAKQLGIEWTTAQVQDLFEHGYKNVH
FFTVSAVDSVKQIAKILF
>A0A6I3HXX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSQMREKLENTNDLVFTAEFPSLDGGGMAKVEKNAARLAPWFVGVNATDNPAAHAHASNT
ASAIAMKMHGIEPIMQIVCRDKNRLAIQADMMGAALHGIDNISLLTGDDVTAGDEPESRR
VFDIDSTQAINIARIITTGKYLSGRKIDPAPDFYISAVENPAAPPFDYRIERALKKYRAG
AKYLQLQICYHSDRLEKFCAGVAKIAPDLKLIPTIVLVKSAKPMSFMHDKVPGIDIPQDT
LNRVSAAADQAEEAYKLTVELAKHALTLPSVRGLHVTDFRHDDSLDRFMYDLGQKPRN
>A0A0J6RDP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium indicum|TrEMBL
MYATSFRPSRESCRPIRVSFEFFPPKTPEMETTLWSSIERLAPLSPSFVSVTYGAGGSTR
ERTHNTVSRLVRETDLKPAAHLTCVAATKGEVDEVVRAYHEAGVRHIVALRGDPADGVGT
AYAAHPGGYERSCDLVAGIKRIGDFEVSVSAYPERHPEAGSLDQDLDALKAKVDCGADRA
ITQFFFDNDLFFRYLDRVQARGIDIPIIPGILPVQNFKQAANFARRTGASVPDWLAARFE
GLDDDVATRKLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRAAPAAAE
KAAA
>A0A369U9P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus versutus|TrEMBL
MTTPAISFEFFPPRNLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETLQIVQDYAAAGVHEIVALRGDAPQGQDRFTPHPEGFANSV
ELIEAIAARGDMTIRCGAYPEPHPESPDTAADVAWLKRKVDAGATSAMTQFFFDAETYFR
FRDACRAAGIEAPIIPGILPIQSWAGTRRFAERCGTSVPQWAEDAFAAAGKEGEAQLALD
VCVKLCERLVEGGVDKLHFYTLNKPELVLKVCAALGIEPKGEFSRVA
>A0A6I3ECF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVVRTSYSLEFFPPKDGEGEVRLWAALEALKPIAPEFVSVTYGAGGSTRNRTIGVTEEVT
HRTKIPTVAHLTCVGSSRQELISILHMYRSAGIRGVLALRGDPTGGPRAPWTPTSDGFTH
ADELVQLIHEFGGFDIGVAAFPDGHPSSEGDSVKDIDVLLRKEFLGASFATTQFFFEVSK
WEQLVYALAARGSSLPIIPGILPITNIKQLTRMAELGGTPIPPSISARFAAIDGDIQGTH
ELGIEIATQLCEDLLRAGAPSLHFYTMNSPTATLEIYGNLNHAH
>A0A7Y4KUH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sandramycini|TrEMBL
MANGLPSTLPGGTPTIRELLASGSRSFSFEFFPPKTPEAEEVLWRSLREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPIGHLTCVSHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWVAHPEGLNHAVELVELIRSLGDFCVGVAAFPDKHPEARSLEDDAQVLAA
KAQAGADYAITQMFFGADDYFRLIDRAAALGCDIPVLPGIMPVTNIKQIERMAELTGMAL
PAAVTDRLHAVEDDPAAVRQVGIEIATELCERLLEGGAPGIHFITLNRSTATRQVFQNLG
SHATV
>A0A474WEF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QDGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDDVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A3R9IJQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLQIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A0F5B929|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0N0G5M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. lachrymans|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A5I2FL89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Alachua|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2Y9QA80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delphinapterus leucas|TrEMBL
MVNEPRGHGGPSPRWEGSSSGSESSKDSSRCPTPVLDPERHERLREKMRRRVESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKRLGLKNILALRGDPIGDQWEEEDGGFNYAVDLVKH
IRSEFGDYFDVCVAGYPKGHPDAESFEAGLKHLKEKVAAGADFVITQLFFEADTFFRFVR
ACSEIGITCPILPGIFPIQGYRSLRQLVKLSKLEVPQQVKDVIEPIKDNDAAIRNYGIEQ
ALSLCRELLASGSVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPVVGWGPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGDNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQHIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLSGPHQSKRETEAP
>A0A2N5CSC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter flavus|TrEMBL
MTLPPTRRVIGPVARAGERPVGAVRPRVSFEFFPPKTEKMEANLWEAITRLAPLDPAFVS
VTYGAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRAEVDEVIHDYWNIGVRHVVSL
RGDPPPGEGGIGGVYVPREDGYRNATELTAALRGVAPFEVLVGVYPEKHPESPSLDHDID
VLKAKVDAGATLGISQFFFDIDAFLRFVDKARAAGITIPIVPGIMPVTNFKGLKTMSAAC
QTTVPSWLANLFEGLDEDPETRRLIACSVATEMCAKLQEQGFNDFHFYTLNRADLVYAIC
RVLGVRENAPAHEAAA
>A0A5C6L380|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKDGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVEAGADYVVTQMFYDNRKYVDFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAMKCKDDKEARALGIEWCINQCRELIAYGVPGIHF
YTVGAVDNVKEVATAVY
>A0A356NTV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MASTIEMISKAATDWSIEVTPTGATKIESFRDCLPPGTTVNVTFLPGTDPAETIAVAERL
HNDGMRPVPHLAARSLRDADQLDELLTAFTSRCGVDEVLCIGGGVDKPVGTFDATIQVLE
AGLIQKHGIRSVGVAGHPEGSPDISDEEVAEALAAKNALAARDGLNLYIETQFCFEADIV
LDWERRVRAAGNTLPIRIGIPGPATIKTLFRFAQISGIGPSMRFIAKQAKNVAKLMTVQS
PHMLIAGLAEGMAADDACLIRHFHYYPFGGFARTAAYAGAIAEGNIELLPKGGFDVIAN
>A0A8G9A9L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carnobacterium maltaromaticum|TrEMBL
MGLKEVLGTKLLIADGAMGTLLYQYGIDRSHEELNCSHPEAILKIHQDYLAAGADIIQTN
TYGANYIKLARYGLEDQVQKINRAGITLAKEARGDKEAFILGTIGGIYGAVDTKIHDPGM
EEISRSFKEQLYCLLLGGVDGILLETYYDLNELKTVLAIAREATDIPIIANVSIHEVGIL
ANGQSLATALEELADLGANVVGTNCLLGPHFMAQSFESVPLIPGKVLAAYPNASFPTMEN
GRIVYQKETDYFKLFGELFRKEGVGLIGGCCGTTPEHIAAYREGLTTLDLVAQKKVKALT
TYRFQAKQETGKERLLDKVQREFTVLVELDPPRTFNTTAFFKGAARLKEVGVDAITLSDN
SLASARISNMALSAMLKYEYDIQPLVHLTTRDHNLIGLNSQIMGFHKLGIQDVLAVTGDP
AKVGDFPGASSVFDVSSFELIKLIKNFNQGIAYTGKNLREKTNFQVAAAFNPNIPRLERA
GRLLKKKQEAGADYFITQPIFDSEKVKILKEVMKTAGVTIPIFIGVIPLVSSRNAEFLHN
EVPGILLTDETRERMRMAEEEGRGLEVGMTIAKELIDEICQEFNGIYLMTPFMNYEISAE
LCEYIQAKKQQEKSICSCGQVHSQ
>A0A451B4A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. UNK|TrEMBL
MNPSDSNPLVFSFEFFPPKTSQGHDKLRATWRRLSQLDPDFFSVTFGAGGSTQVGTVETV
LEIHRDSGIDAAPHLSCIGSSRVKIREILAHYLSNGIRRIVALRGDFPPDMAEPGEFRHA
NELVEFIRVEVGDKLHIEVAAYPEFHPTAPSASADLENFKRKVEAGANSAITQYFYNKDA
YLRFVDNCQRIGVDIPIVPGIMPITNYVSLAGFSERCGAEVPRWLRWRLQEFGDDMKALR
AFGTDVVTELCQELLSAGAPGLHFYVLNRAEPIMTIWKNLDLSNRQGPR
>A0A842APL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQVAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKGIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQGKQEVAEQIISQN
>W9BJ75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A690LLL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKEGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A3R7GLE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora kernoviae|TrEMBL
MGKIIESIRSTYAATADDPTTRPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTDQLKRILKNARAAGIRNILALRGD
PPIGAERWAPVEGGLSNAMDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMVQWISDCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPTEVLTDLDAIKNDDAAVRRYGTQLAVETCRRLLKVGVHSLHFYTMNLATT
VTQVLEGLQLLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRIELWGTPQAEEDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAVIRDNLQWLNYNGFLTINSQPRVNGAPSSDPSVGWGGDDGVVFQKAYVEFFVS
PEKLTHLVKVMNRDYPQLSFHALNRQGEEHRNTPLHSVTAVTWGVFPGTEIVQPTVVDSD
SFAAWKDEAFELWQTQWASVYAEDSRSHEVIQHIYDTYFLVNIVDNDYANDESDIFSIFT
RIITQAMDKEQLRERVLDLETRREKMYDTLASFQSLQEELSGDLRAAHTEIASVRNENLE
LKDKVRQLQSQLALTSL
>A0A3M7HML3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGIRNILALRGDPPRSDE
YNDPNNPLSEQDDSNKDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLVEKTAAGADFIMTQLFFDVEAYNNYEKRLRSHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLSRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTL
NLEKVVTQILERTGLIPPATPVIKTADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSS
NRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPINSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLKGEIEA
MPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSTDPIYGWGPKNGFVFQKPF
VELFLPSADWQRLKPILQSDDQVTYYAGNAAGDFQSSDENSVNPVTWGTFAGKEIITPTI
IEADSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDA
LIAA
>A0A849UW63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferruginibacter sp|TrEMBL
MKVIDHLSQAKDTVISFEILPPLKGKGIQSLYNHLDPLMELKPAFINVTYHRSEHVFKKT
ADGNFKKVVVRKRPGTESICAAIMNKYNVDTVPHIICGGFDINETEDALINLNYLGIDNV
LLLRGDAAKNEANFEPEIGGHNYTIDLVKQVQNLNAGIYQEEDLKNTASTKFCVGVAGYP
EKHFEAPNMDTDLQFLKKKVDAGADYIVTQMFFDNAKYFAFVDACRAIGITVPIIPGLKP
IYNKKQLTMLPKVFSIELPNDLSDAIIKCKEDADVEKVGAEWLLQQSKGLKDAGVQALHY
YTLGKPNLVANVVRQLM
>E9DEV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccidioides posadasii (strain RMSCC 757 / Silveira)|TrEMBL
MHVKEKLAHSEASGRPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPPREKES
WAPTEGGFRYAKDLVKYIREKYGNHFDIGVAGYPEGCEDEEDPETLMKHLKEKVDAGGTF
IITQMFYDVDIFLDWVKRCRENGIQVPILPGIMPISTYASFLRRSNWVKCKVPESWMEAL
EPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQATKMVLEELKLIPSYETP
LQKPLPWRQSLGLGRRDEDVRPIFWRHRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSIKDLSAIFIRFLEGGLDRLPWSESPITEETDDIKQDLID
LNNRGFLTINSQPAVNGMSSSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNP
DLTYYAINKNGELKTNTSDSPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRLGDDWA
KCHDARSPSRQLIQRVMDEWYLVNIVNNDFHKTHDIFDLFNDIVVKDLDVEATGIEEPTS
QPANTNPERQNGDAAQTKDISVATNGTSN
>A0A2E0PZ07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Legionellales bacterium|TrEMBL
MQSQKQYRPKFSFECYSPKTPDSIASLQSTQLELAELNPDFFSVTYGAGGSTRNMTFETV
MDIRNKTGIECVPHISCVGNWDNDIRSMLQKYIDHDITRIVVLRGDLPSGTVGYGQFQHA
NELVEFIRKETGDHFHIEVAAYPEFHPQAKSAAVDIENFKRKIDSGANSAITQYFYNPFS
YYRFVECCEKLNINVPIVAGIMPITNCTQLVRFSEGCGAEIPRWILKQLYDFGDDRDAIF
KFGVDVVTELCDQLLSNGTPGLHFFTMNRSAASNLIWKNLGLDERQTA
>A0A5H9TDZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Sandiego|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6P7EJE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ovis aries|TrEMBL
MVNEPRGNGGPGPRWEGSSSGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKH
IRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQDERETEAL
>A0A0S4TY74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia solanacearum|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILDTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRKEMNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNPDAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLLRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>A0A661L204|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSFQKRLVAGDFVVLAEFDPPKGVDASDLVSNLIKIKGRVDGVIVPEMAQAVMRMSAMGG
AALMEQHGMETIMQICSRDRNRLALQGDVLAAYFLGIKNLLVVPGEEIMYGDHIDAKQFA
DIDELTLLRAIKGLQNGVDMAGMELKGSPKFLTGCSIKPAKNEIALEAELELTQKKVKEG
AQFLVTPPVFNINAFTYFMEKAKGLGIPVIATVFLLKSVGVARYISTNVPGPPIPEEMIS
RLRKAPDRINECINIAGELITSLKELCQGVQLVTMGWENRLPAILDAAKI
>A0A1X3FAR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium canariense|TrEMBL
MTDATMPAHTGGQDGYLKRPAISFEFFPPKTEDMERNLWDTINRLAPLDPKFVSVTYGAG
GSTRERTHATISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPPG
GIGTAYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDDDIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARAFVTRAGTSVPDWF
AAKFEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A162QAB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum incanum|TrEMBL
MHIKSMLDETRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREQEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGATF
IVTQMFYDADNFIRWVGKVRERGITVPIIPGIMPIATYSSFLRRAKHMNCKVPEEWMTAL
EPIKNDDVAVREVGKGLVAEMCRKIVAAGIHHLHFYTMNLAQATRMVLEELNWMPTSDRP
VKHALPWKQSLAHGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSIKDIANIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSNHPVHGWGPANGYVYQKAYLELLVHPDVYAEIVSRVEKNP
DMTYYATTKNGNLKYNATNDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGIDW
AHCFEAGTPSRVLIERIMNEWYLINIVNNDFHQKTALFDLLEGLEVKEYTDIPAEPQTNG
AAKEHAAETNGNSVPVTAN
>A0A352RFW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKVLFGESDSFESNMTIETTDDLQDNLEQQTKWSMEILPHNFADVSLIPDFINEVYITMI
PGAACWETIQTAQQIKAVGKHAVPHIAARSFAGVEELSACLSGLQEAGIERALLIGGGNS
QPAGDFSCVMDLLKTGLLAKYGINAFDFAGHPEGNPDDPNSEFHLLEKLRWTAEREISAR
IVTQWSLDAKKTNNWISDLREKGVSNPIHIGVPGPSTIKTLMRFAKVCGVKASTKVLRKQ
GLSLSKLMFVNKPDKIISGLRGYDQLHLYPFGGIEKSAAWLTEWQTNVSFE
>A0A496SAP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MKFREKLEKNKFVFTLEVEPPKGVDIETTLKEVLPLKKYIDAFNVTDMQSANMRLSSWAL
AAKLKLNNLEPILQLTTRDRNCLALQGDLLGSYALGVENLLLLTGDRPICGDHPKAKEVF
EVDSLGLIKIASQLNSGYDLSGNLLKGKPNFYIGAALNPMAKDVDRELKRAEKKIKLGAS
FFQTQPIFDVKKFYVFMKKIRRLRTKVIAGVIFLKSHKMAKYLNENVEGIEVPHLYLDRL
EKAKNKKEEAIRIAKEIIAELKDICQGVHIMSLGWYSTARELFL
>A0A1A6XZ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIEFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLVEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A6N2SDH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium dentium|TrEMBL
MHSPLFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGRSSDRTLTARIAHTVS
EYGIPCVAHLTAQYLNKDDVDQALDMFDEAKVSGVLALRGDRVEGAEPAGVFEHASDLAA
YIREERPNLKIYGACYPEKHPQSATLEDDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KVRAVGIEIPIEAGIMPVMNAKSVRRMAGICQSRVPAKLEVMLDRWGGDNAVLKEAGIAY
ASEQISDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A7C9FUQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter hepaticus|TrEMBL
MCSFSFEIFPPRKDENIKNLDAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEK
YKIPSIVHLPCIHSSKEKITQILQQCKDRQLNKILALRGDVCNNLEKSKDFSYASDLISF
IQKYKDFEIYAACYPEKHNESKNFIEDIHYLKNKVDLGTNKLITQLFYDNDFFYTFKQNC
ALANINIPIYTGIMPITNKRQVLKITQLCGSKIPAKFTKILEKYENNTLALEDAGIAYAI
DQIIDLITSGVDGIHLYTMNKSRAAIKIYEAIKYLIKVS
>A0A520YTQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium|TrEMBL
MPLQKKHRLSFEFFPPKTEKGASKLRATRNQLARLSPDFFSVTYGAGGSTRDNTRDVVLE
GIRDGYAIAPHLSFGGDTQDSIRSLLDQYAAAKVERIVALRGDLPSGYGDGSRLVHASEL
VEFIRAHYGSAFHLEVAAYPEIHPEAESYDSDIGFLKQKFEVGADSAITQYFYNADAYAR
FMESCARAGINKPVYPGVMPITNFENLKRFSANCGAEIPRWLGYRIESYGDDLHARDQFC
IEFISELCEKLLAMDAPGLHFYTMNQAASVEAICQRLGVNAS
>A0A2I4N4J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIHDTLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKNIIGE
YNYAFELIEKIKANNKFGVSGACYPEGHIECESLEQDIRELKRKVDAGAEHLISQLFFDN
NVFYEFLNKAQQKNINVPIQAGIMPVVNKKQIERIVEISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A660WGQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MSLLKEKLEKGDFVVTSEIGPPKGVNIEPYLEEADKLKGKVTAINVTDIQSAVMRLGSLA
VCHLLKERGIEPVYQLVTRDRNRLALQSDLLSAYVLGIENVLCLTGDHPVLGDHPQAKPV
YDLDSVQLLKAAKSLNEGEDMVGNPLEGRPQLFLGAVVNPGIEPLEPQIIKMKKKISAGA
QFFQTQPVYEVDKFARFVEKVKDLGVPILAGVVLLKSAKMAKYMNENVSGVNVPQELIEE
MASVSKEDRPKKSVEIAVRLIRKLKPLCQGIHIMPLGWDRYVPDILKGIDLA
>A0A6N9VDF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces microflavus|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRIEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPLAEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A0P7CC14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A5E4RLJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea cepalis|TrEMBL
MNDSLDKRTIMTQPSFSFEFFPPKTAEGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQG
TLDTVVEIQREGVEAAPHLSCVGSTKDNIREILQTYRQHGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGEWFHIEVAAYPEYHPQAKSPRLDLEHFAHKVKAGANAAITQYFF
NADAYFRFVDDASRLGVDVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
DSIRAFGLDVVTALCERLLAQGVPGLHFYTLNAASATKAMWQRLGL
>A0A6B3ZLN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKNIIGE
YNYAFELIEKIKANNNFGVSGACYPEGHIECESLKQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLSKTQQKNINVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A2X2YKQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobiluncus curtisii|TrEMBL
MTIKDLYAAPRPAVSSLPESGATSRRTGSGRDLRVSYELYPPRNSRLTSQAWAGIDRLLD
SRPDYVSVTFGTSGTTPDASQSVLWHALKRSGRPVLAHLTCLGKTRTKLVGIIQDMMDLG
VRDFLALRGDEAPDSASGAAEPNEFDRAFQLVQLIREVSADYLGDAHAVSIAVAAYPAGS
IQTRTDAVQALVQKQAAGADFAITQVFYQARDYAELVQSATYQGVTIPIVPGIIPFTDMH
RLQRLEGLTGVPVPERIKSIANISDPAERILESLGATLNFVNDLIEANAPGIHFYTFNRP
RPVLDLVEHLRSRGFTHVDQEDSQDLLGLMNATMHRISP
>A0A1H0F5Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. BS3759|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A4U1Z052|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio kanaloae|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPVGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVATL
>A0A1C5Y170|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MIKDLFSQKQTLSFEVFPPKKDDEFTNAQNVLHQLSELQPDFISVTYGAGGSRSKRTVEL
ASFIQNSLHIPAVAHMTCVGSSKEDILTVTDDMKQAGLSHVLALRGDRPTWMDDAQFENR
AFAHASDLTRFLKEHTDLEVAGACYPEKHFEAESLDSDIAYLKEKQEAGAAFFITQLFFE
NDSFYRFLEKKNHAGITLPVCAGIMPITSAKQLGTTVTLSGSSVPKELADIIATYGENPE
DMRKAGIDYAIRQILDLKQHGADGIHIYSMNKPKTTRTIVEAIR
>A0A4Y6N8S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Indiana|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7V0VD47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MVMKSFRERLGKEIIVFDGGTGTYLYEKGIFINRCFEELNLTNPELVKQVHRDYLLAGAD
VIETNTFGANRFKLTPHGLNEKIYEINFAGAKLAREVAGDNILVAGSVGPLGVQIEPLGK
IGYDEAKDYFKEQIQPLIDGGVDLIILETFTLTAEIIQALRAVREINPEFPVIAQVTVNE
EGNLLSGEPVEKFVDQISKYNPDVIGFNCSVGPKPMLDALEKLRELTELPISIQPNAGYP
VNVGGRNIYMTSPEYIAEYSKRFIQTGAAIVGGCCGTNPSHIKAIRRAVQALQPSKRLDI
KVEELKIEQPENVYVYKLHEKSRLANKLLREDFVTLVEIVSPRGVSAKKEIEKARKLYHF
GIDAINIPDGPRAMARMSALAMAVLIQRDVGIETILHFACRDRNVIGMQSDLLGAWALGI
RNILAITGDPPKLGNYPDATAVFDIDSIGLVNLINRLNHGLDLAGNPIGEATGFSIGVGV
NPGAINLDEELRRLDWKVQAGAEYMITQPVFDIRILERFMKKIEHYKLPLIVGIWPLVSY
RNAEFMNNEVPGASVPQEIMDRMRRAQEVSKEAAFEEGVKIAKETYDYIRSEVNGVQIAA
PLGRIEAIFKMLSDEEFYTM
>A0A176NL96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas thivervalensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGADSAITQYFFNADSYFY
FVDRIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDASSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A2X1AMV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas diminuta|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRSAVNVSFEFFPPKSDEAEANLWKAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIEGYKTIGVDH
IVALRGDPPGAAGIGGAYTPRADGYANATELTAALSRIGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLKRMT
AACGAALPDWLAGHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAVA
>A0A348MND1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter sp|TrEMBL
MSIIPRVSFEFFPPKDIEASFRLWDTVQMLAPFQPGFVSVTYGAGGSTRALTHQAVTAIG
RKAGLNVAAHLTCVAATREETLDIARAYHAAGVRDIVALRGDPPKGKSGFSPSNGGFASS
VELIKALAQTGDFNLRVAAYPEVHPDSQGAERDLDWLKAKIDAGATSAITQFFFKADTFL
RFRDRVLAAGIDFPIIPGIFPVENWAGVKAFAKRAGSLIPPVLDAAFSVAARDGREELLS
LTHCTQLCDQLLSEGVEDLHFYTLNRPQLTRDTCLALGLKAKSTLQMVA
>A0A3R9HKW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium pisi|TrEMBL
MALKNEGRGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWDPDFVSVTYGAGGTTKAPTL
SAVTRFLSQTPLATASHLTCVGATKEETHHMIDTFRKVGVKHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGITIPVVPGIMPIQNLTQLKRFAGACGAVIPAFLDERFEGFDD
KPEERAKVAADVAAEQIEDLVRRGLDEFHLYTMNRAPLVSAVLDNLGFSRRAQKSAGAAA
>A0A2S9VR55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus pentosus|TrEMBL
MNLRQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHQSYIQAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVRIAVTAREHADHPVYILGTIGGLAGDTDAAVQR
ATQAEIAANVTEQLTALLATEQLDGILLETYYDLSELLAVLKIVKAHTDLPVITNVSMLA
AGVLRNGTSFTDAIVQLHAAGADVIGTNCRLGPYYLAQSFENLAIPADVKLAVYPNSGLP
GTDQDGAIVYDGEPSYFEEYAERFRQLGLSIIGGCCGTTPLHTAATVRGLSSRSLVPHNA
PTHVAQAPTLVTTKSQHRFLHKVVTEKTVLVELDPPRDFDTRKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTAIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAV
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TDVSTKSISRKLSYGCDYIITQPVYDLANVDALADALAANQIDVPVFVGVMPLVSRRNAE
FLHHEVHGIRLPKSVLERMQQAELDGNERAVGITIAKELIDGICARFNGVHIVTPFNRFK
TVLELVNYVQQKNLTKVQ
>A0A0A2SK60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus gonensis|TrEMBL
MGLLDDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIESGAEVIQTN
TYGANYVKLARYGLQDDVKKINEAAVGLAKRAAKGRAYVLGTIGGLRSTNKSAISLEEVK
RTFREQLYVLLNEGVDGLLLETYYDFEELQTVLSIARKETTLPIIAHVTLHDIGVLQHGM
PLAEALTELERLGADVVGLNCHLGPYHMLRSLEEVPIPTRAFLSVYPNASLPQYRDGRFI
YETSEQYFEETARAFREQGVRLIGGCCGTTPKHIAAIARALSDRTPVYKKEVKQRHPIVV
QEEKQTTAPSLADIARTRRSIIVELDPPKKLGLTTFLEGAKALKEANIDALTLADNSLAT
PRISNVAVGTIVKQQLGMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRI
EKKIECGAHYFLTQPLYSEKQIEDVYEATKHLPTPIYIGIMPLTSARNADFLHHEVPGIT
LSDDIRNRMAMCANDRVQSTKEGLAIAKALIDAAFDLFQGIYLITPFLRYDMTVELVRYI
HEKERLAKERTVYYG
>A0A137YFB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKAELRELLNLYKSAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVQTPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A2T8Y682|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella infantis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J6NUS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MNSKLRGTTFSLEFFPPKDEAGESRLWLALSQLQPLAPDFVSVTYGAGGSTRDRTIRVTS
EITKRTSIPTVAHLTCVGATRDELVEILNQFKNSGIDSILALRGDPTGGPTAPWQMIPNG
LNYAKELVELAVGMGFKAGVGAYPDGHPASNHDLAKDIEVLLAKEKAGATFATTQFFFEI
DKWQAIVDKLAKAGSKLPVLAGILPITNVKQLNRMAELSGMKVPTAIADQFNKYADDLEA
TKEIGIEIATNLGAQLLKRGVPGLHFYTMNSAQSTVAIAKNLGLIK
>A0A6J6TB61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSILREKLENTSEQVFTAEFPSIDGGGMVSVEKNAARLAPWFDAVNATDNPAAHAHTSNT
TTAIAMQMHGLEAIMQIVCRDKNRLAIQSDMMGAALHGITNISLLTGDDVTAGDEPEARR
VFDVDSAQAINIARIMATGQYLSGRKINPAPDFYIGAVENAAAPPCDYRIQRALKKHRAG
ARFLQLQICYHPDRLEAFCRGVAEVAPDLKLIPTVVLMKGAKGLSFMNDKVPGIDVPVDT
LKRVQSASDPSVEVNKLTLELAQHALTLPGVRGLHITDFRHDDTLAIFMNDLGRTPKRQG
>A0A440WAR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MSIRHQRDENPAGVHLPLDHLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVF
LGAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRNFMQKARDLGHTEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIAGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>A0A5H9C2B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Rissen|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0M4DA34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces pristinaespiralis|TrEMBL
MSTLREILAAPGPSFSFEFFPPKTAQGERTLWNAIRRIEPLAPAFVSVTYGAGGSSRDRT
VAVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGVHDVLALRGDPPGDPNAPWT
AHPDGFTHAHELVSLVRRSGDFSVGVAAFPERHPRSADWDDDIRHFVAKCKAGADYAITQ
MFFHAEDYLRLRDKVAAAGCDTPIIPEIMPATDVKQIARFAQLSGATFPAHLAGRLEAAR
DNPAEGHRIGVEYATAMADRLLAEGAPGLHYITLNRSTATLEIHQNIQNSRSAHALAAGR
>A0A1B9LPD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVQPKDDF
RFASELVTFIKENGDFNVIGACYPEGHLEAATLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYTFLDKARDIGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPEAF
RDAGIAYAIDQIVDLVSQDVDGIHLYTMNNSYIARRISEAVSTLLAVPKSQ
>A0A514JYC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces calvus|TrEMBL
MALGTASTRTDRARTVRDMLATGRTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQS
>A0A6H9XJR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium matruchotii|TrEMBL
MTQQPLPEPTPARYQRSITDVISSPAPGRIPFSVEFMPPRNDEAETRLRTAAEIFHDLGV
AFVSVTYGAGGSSRDRTMRIAQDLARMPLTTLVHLTLVGHTEAELVEILSDYASLGLSNL
LALRGDPPGADPLGEWTPVPGGYRYAEELIWLTKRLEATKHFQVGIAAFPEGHHQSESLA
ADTKYTLAKLRAGAEFSITQMFFDVDYYLRLRDRLASADAELGSRPIIPGIMPITSLKSV
RRQLQLSGAKLPARLEERLVAAAAGDEEANRDEIRKVGIEESTLMAERLIAEGVPDLHFM
TMNFARATQEVLHNLGMAPAWGREHGHDAVR
>F6F244|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium chlorophenolicum L-1|TrEMBL
MKLAYADQHAPTVDLIQSFSLEMTAKDIESLTDAAPLIPAGTPISVTYLPGEEMPARVAA
AQAVKNLGFVPVPHISARRVLSRDDLQQFLAMLDEHVGIERAFVIAGDPASPMGPYEDAL
AIIRDGLLPAVGVRKVGISGYPEGHPDIDKPKLAKAMHDKIAALSDQGLEAEIMTQFAFD
ADAILVWLERIRQEGVTIPVRVGVPGPASVKKLVRFAARCGVGASAKVMLKYGTSITKLL
STAGPEKLIEELADRIDPSVHGDVLLHFYPFGAFVDTAQFIANHYGTAKA
>A0A0F8BYZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. 2.H.A.1B.4|TrEMBL
MLFNFREKLNSRKFLVTVEVSPPKGTRFSAPLEDACQLKGVADALNVTDNQCSIMHMSSL
AFSKLLLDQGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDHPTCGDHPGSKP
VYDLDSVQLIELVRKLDSGIDFAGKSLDGGTSFCAGAVSGIDPKNTLQLIKLEKKVKCGA
DFIQTQAVYDVGMFEEFIEAVNHLEVPVIAGLIPLKSLSMAEYMNKNISGIHVPEEIMLR
MKDASSPIEEGLSIASDTIKELTKLSRGVHIMPIGSHKNTPRLLSMAGISGK
>A0A7V2Y083|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MNEDPMGLLAKIDSGKPILLAEILPPRGGDAAPVRLAARRFAGKVDAIGVSDNRHGVRMS
ALAAAGIVASEGVEAILHVVTRDRNRIALLAECLGAQALGVRTIFCTSGTHQTLGVCRPA
KNVYDIDTVQLLDALAHLAEGSAAYPDRFESAGPFCLGAVAAPFADPLEMQIMRLAKKVN
AGARFLITQPVYDIGRFRLWWDAVVARGLHERAAILACIQPLCDAARAIGFASSRPSPAI
PQATLDVLSSAGDARAQRAAGIGMALETIKQISDFKGLRGFQISAENDEDAALEIIERAG
WGVR
>A0A7C3X1H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MDLVSLYKKGKPIVSFEFFPPKTWQGIAELYEHFHELMKCNPGYITCTYGAGGNTPLDKA
QKRTLEVLRWVRGDYPNIPVVSHLTCVNATQADLRNYLYKVKELSASGIVALRGDAPDKK
QMFVPPPNGFRYAVELVRLIKSEFSEFNILVGGYPEKHPEAPSLEEDIQHLKEKVDAGGE
IILTQLFYNNEDFYRFRDLCEKIGIDVPIVPGILPVTNLAQVKRITSLCGAKLTPVLLER
LEKHEKDEEGQFSVGVYYATRQVEDLIQQGVPGVHFYVLNKSRAAAHICRALTL
>A0A7V2Y2Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MNFLARLLTRTENFAKGVLFDCHHCGQCVLSHTGYTQCPMACPRQVRNGPCGGSMDEHCE
VFPDRPCVWARIHQLTDKNGTSTPPLLRSPDPKLFFTSSYMNYFTGKDLLARTPIPYLDL
GTNRKQQPPQTASRLERKLRAGQFVFTSEIRSPRGAEPEKVQQQAELLRDHFDALNATAY
LNGKPSMPSAIASAQIVKCGVEPICQSVCRDLTKTAFISELITNKMNGVHNSLCITGDYY
QGDPGVKQVYDMDSSLMIYEARHLREKGVIFFTGDKMKDPPKPFIAGAINPFTTPWNVPI
RRLKQKVAAGVDFIQTQVILDLATFKEFMRRVHEEGIDNDVFILAGLPVIISKKAFEMMP
GVPGIRVPKNIAARFAQTQDIVQEGVALAREMIAEVRAIPGVSGVHLMLFGLDHKILPAV
VEGLRDKPAVELTAAECGS
>A0A3R6UW16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM27-31LB|TrEMBL
MNFKDYIKTHNILADGSFGTYYAEKYHTNEAPEYANIYHKDRVTNIHSSYLDAGANLIRT
NTFATNTMSMQKDFSFVEDNIKEAVSLAKIAVKLSGKKDIFIAGDIGPVSTVSGVSNENL
INEYFNIAKTFADEGIEIIQFETFMSLDVLADVIPKIKKELGLFIMVSFSVNQLGYSASG
LSAKNLINDICAVDGVDAVGLNCGIGPYHMYNILEKIKLPEDKVLIAIPNAGYPVLTRNR
MEFNSHPEYFAEKTKELLSLGADIIGGCCGTSPEFIKSLYDIMSMDIKADKKIQKTDAAD
EKVSKRCGFLYDENGRKKDKKFIAVELIPPFNTDDEKLLESAHYLKNAGVDVLTFPDSPS
GRTRVDSVLMAAKVYRETGIDVMPHVCCRDKNAFAMRAMFMGAKINDIKNFLIITGDPVP
ASARDLVKSVFNFSSVGLMKIAQEMNREVFNENPLNYGGAINQNLINLESIINTTKRKMD
AGASFFLTQPVFSKEEADRLRKIKEETGACIFAGIMPLISRRNALFMKNEIAGINVTDEI
VNRYPENGSKEDGEKVAVELAKEIISYIDDFADGYYFSFPFNRVYLLNRILG
>A0A3L9Y5L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodophyticola porphyridii|TrEMBL
MTAAPSVSFEFFPPQSLEASFRLWDTLGTLAPLAPEFVSVTYGAGGTTRTLTHEAVKTIH
SNFGVKVAAHLTCVDATREETLAIADSYAEAGVTQIVALRGDPPKGAGAFTPHPDGFASS
VELIEALARTGKFTLRVGAYPDPHPDAPDMAACVDFLKRKIDAGATSAITQFFFEADTFF
RFRDACVAAGIEAPIIPGILPINNWTRVRRFASACGAVIPAWLDEAYAAAIRDGREDLLS
TALCSELCTDLIEGGAGDLHFYTLNAPDLTRDVCAALGVTPKLSLAEVA
>A0A517MBS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseimaritima multifibrata|TrEMBL
MKLAEFYRNGHRGLSFELFPPKTESGRQALYEHVDRLMAFQPDYFTCTYGAGGSTQGTTL
EVLSEVRRRTQLPVASHLTCVGATCDEIREYLKEAESRETDFIVALRGDPPKGETTFQAV
DGGLQYANELVELIRAEKKPFGIAVAGYPEVHQEAVDAASDLANLRRKVDAGADIVVTQL
FYDNADFYRFRDACDLAGIRVPIVPGLLPITNLQQALRITSMCKAKLPPALVARLEEKPE
DADWQFEIGVEHARQQFLDLMDNDAAGMHLYVLNKSQAAEKMLEGYTR
>A0A1A9R9N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. ALS9|TrEMBL
MSSQEHPLGISFEFFPPNTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTRQVVR
EVSESGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIREETGNHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSDAISAF
GTDVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKIVDNLTD
>A0A2T5X5M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacteriaceae bacterium MWH-Ta3|TrEMBL
MVNPFGEGAVPVSFEVYPPRTPDKAPSLYETIRALAAVHPRFISVTFGAGGSSRRSSLEV
LTHILHNTHVQPMAHLTCVGTTHAEAADLVREFLDAGITSFLALRGDPPTDEAHIDDFIG
DVKTAAELVQLIQHVQSERAPWTDYPVMGSTARRIDPTPAPVNVAVAAFPNGHPESGATR
ADIDSLLAKQAAGANLAITQLFFHSDDYFRFVDKARTAGVTMPILPGIMPITSHQRLTRV
VELTGEKEPSELSINLQIEPTAEGRAAVGVDYATKLVNELVAGGAPGIHLYAFNRHDTVL
DVLHAARLVP
>A0A0A0F7S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter arseniciresistens ZS79|TrEMBL
MTPISFEFYPPKTDEQRAQLDRTATRLKELAPDYVSVTFGAGGSTLSHTPEAIQRLRGQH
AYDAAPHITCMGGSREEIRGLLKLYRALGARRLVTLRGDLPSGMVSPGDLRYASELVEFI
RTETGDHFHIEVAAYPEMHPQARDSRVDIENFVRKVRAGADGAITQYFYNADAYFRFVDD
VRAAGVDVPVVPGIMPISNFSQIRRFSEMCGAEIPRWIAQRMQSYGDDAASVREFGAEVV
AQLCRRLIDGGAPALHFYTLNLAKPTLNVLARLG
>Q67LF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiobacterium thermophilum (strain T / IAM 14863)|TrEMBL
MRSSGLSANPSFSKGSLRMEGRGGSAMARLMHRLQQGAFCVTVEIDPPRGAGVAGTLERV
RRFGDRVDAVNVADCPMANVRMSPITLAHLLQRDGQVEAIFHLTTRDRNIIGLQAELLGA
AGLGVRNILALRGDDPSRGDHPDARGVFEVDTIGLIRLAAALNRGQTVSGTPLEQGTDFA
IGCACNPAAADLEAEVSRLEEKVEAGAHFAQTQPVYDPRQVERFQAKLAGRVKIPILYGV
LPLKSYEFADRLNRTVPGIVIPGWVLDRMRGRDEEEGLRLTAELLREIGPHVHGVHIFPM
NSARRVVAVLDLIDELGLRHSVRVGV
>A0A3M2CSG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MRLPEIYAHRRPAISVEFFPPKTPAGEALLAQRLERFRALDPAFCSITYGAGGSTREKTL
EWARRLRNEYGFETMCHLTCVGHSREELRSLLEGLWADAIENIIALRGDPPRGQENWQPH
PEGLRHAVELVRLARSVAPFGIAVAGFPEGHPESPTEQEDLRYLKEKVDAGADVVITQLF
FDNTDFFHYVNAARAVGVSVPIVPGIMPFRTVAQLEKFTTVYARTRNGPARIPEKLRKRL
QGIASDEDAARLGIAYAIEQCEELLDRGVPGIHFYCLNESDAVDAILQSLRSSHRLA
>A0A1W9IPH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium HN_bin10|TrEMBL
MNAIRPILPETSVRANKPRVSFEFFPPRTEALENQLWDSIRKLEPLGPSFVSVTYGAGGS
TRDRTHRIVSRIVRETSLKPAAHLTTVSASRSEVDAVLRDYRNAGVRHIVALRGDPPGGV
GLPYLQHPQGYASAIELTEAAARIGGFEISVAVHPEKHPASPTWEHEIDNFKRKLAAGAT
RGISQFFFDADVFLRFRDKLARAGVYAPVLPGIMPVTNVKGLKKMADACGASLPRWLIHL
FEGLDDDPETRRLVTAVTTAQLCARLAAEGVQDFHFYTLNRADLALAICRILGLRAEEAR
A
>A0A2J0MJX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG_4_10_14_0_2_um_filter_44_9|TrEMBL
MTFKEKLDSGAKILTTEVGPPKGISLDKILAEIEPLRGRVDAVNATDMQSSVVRMGSFAA
CVLLKQRGFEPILQVTCRDRNRLALQSDIISAAALDICNILALTGDHPTLGDHPEAKPVF
DLDSVQLLEVLRRLQTGEDMNANKLSEPVPKFCVGAVVNPGADPLELEIIKMEKKLEAGV
EFFQTQAVYDIRVFEKFLDASKHLKTNILAGIVLLKSERMARYMNENVPGVSVPEGIIDE
MRQAQDKKAKCVEIASRLIIELRSMCRGVHIMPIGWYGVVPAVLDAI
>A0A244E747|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. JS1663|TrEMBL
MRLPLSFEFFPPKTPEGVVKLRAVRQQLYAHQPEFCSVTYGAGGSTQAGTFGAVREILEE
GVDAACHFSCIGATRSTVREQLAALKAMGVKRLVALRGDLPSGYGMGGEFHYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVRAGADSAITQYFFSPEAYFRFVDE
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCERLRAGGAHALHFYTMNQSVATLALLDRLGWGG
>A0A2A5DA93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MTLPEIYNSNDFVLSYELFPPKTDKGAVNLNEHLKKLLTYNPHFITCTYGAGGSTRDKTL
DTLAQVQSLTDIPVASHLTCVQATADEIRTYLQRCLDQGVENIVAIRGDAPEGEDTFEAT
QGGFSYANELVDLIHTDFPQMGVAVGGYPEIHPEAVSADADLDXLKKKVDAGAHIVVTQL
FYDNAPFLRFRDACVKAGITIPIVPGLLPVTNYKQVKRIASLCGAKLPSAFQHALENAQD
DKEEQFKVGVEQAAHQADELIKAGIPGIHFYVLNQSRAAAAVLDALHPLH
>A0A412LI55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF20-14LB|TrEMBL
MRVDEVFKQAASQGTTPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGMSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>H0UZL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cavia porcellus|TrEMBL
MWASKAGISRYSVPPSISSRTWATMNETRGSSGSSSGSEGSKDSSRCSTPGLDPERHERL
REKMRRRMEAGDKWFSLEFFPPRTAEGAANLLAMFDEMAAGGPLFIDVTWHPAGNPGSDK
ETSSMMIASTAVNYCGLETMLHMSCCQQSPEEITGHLNKAKQLGIKNILALRGDPTGDQW
DAEDGAFDYATDMVKHIRREFGDYFDICVAGYPKGHPEAGSFEEDLRHLKEKVSAGADFI
ITQLFFEADTFLHFVKACKEIGITCPILPGIFPIQSYSSMRQLVKLSKLEVPQEIKDVIE
PIKDNDAAICSYGIELAVNLCQELLASGVVPGLHFYTLNRKMATTMVLKRLGMWNEDPRR
PLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQDWNEFPNGRWGNSSSPAFGELKNYYL
FYLKSKCPRQELLKMWGEELSSEESVFEVFERYLSGEPNQHGYKVTCLPWNDEPLAAETS
LMKEQLLRVNRLGILTINSQPNVNGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAQAL
LQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKD
EAFALWIEQWGKLYDEESPSRMIIRYIHDNYFLVNLVDNEFPQDNCLWQVVEDAFELLSR
PAGRSREVEAP
>A0A8I1IN08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus polymyxa|TrEMBL
MKPDLRTVLNREIIVGDGAMGTFLYQLGFPVNTSFEELNITSPDVISDVHGQYLSAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARDAAGPEHYVVGAVGSICGGKRLNISK
LELARNYEQQIDALLSEGVDGILCETFYSLDEIRIALHSVRKYSDIPVICQFAVDQVGRT
QDGFLVAEAFSVLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAKSFVDLGTRLLGGCCGTTPDHIAAISKALNRLQPPPLASKEALS
KESFQVAEQIADEGERGNGRHISEPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHALK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYVMTQPVYDHELIAAIAEATRHLEVPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGPEGRAMGVSIAKELLDTAMEHFNGIYFMTP
FMFYEMTAELTSYVWQKSGRAQAPLFRL
>A0A7X3MNI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga makkahensis|TrEMBL
MSPLTLRPSRQVSSPIKVSFEFFPPRTPEMEATLWASIQRLAPLNPQFVSVTYGAGGSTR
ERTHATVSRIVKDTHLKPAAHLTCVAATKEEVDEVVRSYWDAGVRHVVALRGDPVAGIGT
AYEPHPGGYRQTCDLVAGIKAIGDFEVSVSAYPEKHPEAPSLEADIDALQAKVDCGADRA
ITQFFFDNDHYFRYLDRVRARGIDIPIVPGIVPVQNFKQTANFATKTGASVPDWLAARFE
GLDNDVETRKLVAAAVAAEQVIDLVDRGVSEIHFYTMNRADLVYAICHLLGLRDQSVKVA
A
>A0A8E0WTQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium lucknowense F2|TrEMBL
MTLGFPSVEAAQAWQAPLYADLAGDVNVSFEFFPPKSEKMEEQLWSAIQTLTPLGPKFVS
VTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASRAEIDEVADAYWEAGVRHIVAL
RGDPPEMGAKFEPHPEGYKGAAELVEGLRKRHPFEISVAAYPETHPDAQSAQSDIDNLKR
KLDAGATRAITQFFFEPDTFFRFRDTVAAAGIDADIIPGIMPVSNFAAVQRMSAMCNTDV
PGWMGKLFEGLDDHAAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVAANAV
>A0A6L4AGB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MSFQKRLQAGEFVVLAEMHTPKGVNISRMVTDARRIKGRVDAVVVPDMDNGIMRMSALAG
GVLMQQQGVEAIIHTYCRDRNRMALQGDILAAHVLGIQNLIVAHSEEMSQGDHSDAKTVN
DLDEIGLLGAIRQLQEGKDLAGFDLDGIPSFTVGCTIAPCADDDEMAVELEAAGRKVAAG
ASFVLTPPVFDLERFAAFLPKVEKLGVPVIPTVFLLKSLAIAQYIANSEPGAHISDALIR
RIRKSPDREQEGIQIAGETVAALKKKAAGVMIQTLGWEHKLPAILDIAGI
>A0A6L4AIY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKTESKLEKVLAAGHLAVTSECGPPRGAMPDKVREKGKYLEGVVDGVNVTDNQTAMVRMS
SLAASVILKQEGHNPLLQMVSRDRNRLAMQADIIGAYSLGIDTMLCLSGDHTKFGDHPMA
ANVHDIDSIQMIQMVKRMRDEGLFQGGAEIKSPPKMFIGAAANPFADPFELRVLRLAKKI
AAGADFIQTQCIFNVDKFELWMEGVRAMGLHKKCYILAGVTPIKSVGAARYMKNKVPGMD
VPQDIVDRMAAQPKEKQPEEGISICVETIERLKKVEGVAGFHIMAIDWEEKVGEIVERAG
LLPRPVV
>A0A6G8S8A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lanii|TrEMBL
MPSFSQPFHNHPFTILFEYLCVTTNEAPIRQEFAGFPTAMTLADRVHSDDDMAPLKASYN
YSNSIDKMIHFAGKGRDIEDFSAFLTEAKQANIKHLLLLTGDKLKGHQDGSQGRPRTRYL
ESVNAVMAAKEFGDFHVGVAFNPFKYVEAERDAQYLKLHKKMKAGADFIITQLGYDMQAL
KQAQVFLKDHHYQQQIFACVMPLSLGRANFMVKNKVAGIVITPHMLNVLAEEKQVGQVEH
VYMRCAIQILMCKHLGFAGIHLSSCHQPQDQNRLENYIKQFQHLDLNHLESLWKELWQIQ
TGNEFIPQLNHYSYPATSTQIIKYHQLHLMHEAIFDSKIACQLGRFVFKSKFWNNSFADQ
ALLKSEWISKHRIVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVGETEILRENLIPTVPLEIRGSSSWKNWFLATEA
>A0A1A5R3Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium loti|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILNETSLTPAAHMTCVDAARHEVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPEGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFIQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A101KSC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium loti|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVRRILNETRLTPAAHMTCVDAARHQVDAVIQEFAGMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSLRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHESEAA
GSAAA
>A0A416NKQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. AF24-19AC|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTSSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>A0A259CRP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuricurvum sp. 17-40-25|TrEMBL
MFESFIQKLRHGTFITLETTPSRSAQFAPTIEKIAALGLDSLVDGFSTTDNPLAKLKYNA
LFAAMKLQDRFGKPTLATMSMRDRNRIGLQSDLLGSNESGVRAILALTGDSAHYSDQPHS
KGVFEGNSNLLLDIITTLNSGTDMAEQKLIAPVQEIYPFAVIDSYSKNTNALQKKMVKKV
SHGAIALVTQPVYDTAIAQQLLTMMEEANALNPEREKCILVLGYFPITKLRTAKFLDENV
PGIHVPSSWVEALEKASLVSVEEEYKVGFELSKKLFEDLKALHPKIHIMTANQFELAKAI
LS
>A0A0Q3U4C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amazona aestiva|TrEMBL
MVNETQHSCSASSSSKSDGGSSSGSESSKXSSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCDQTRDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEDVDGFNHAVDL
VKHIRNEFXDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFVITQLFFRSETXLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEEXVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITXAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDXDFPLENCLWQVVDDTFELLNSQTQQ
>A0A5C1NLT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. Y2R2|TrEMBL
MSAQQHPLGISFEFFPPNTDAGRDKLMQARDMLAERNPRFFSVTYGAGGSTQHRTIDTVQ
AVRQCGISTAPHLSCVGSAKSQIRDLINHYKDEGINSLVALRGDLPSGMGSIGELRYANE
LVEFIREETGDHFEIAVAAYPEAHPQASNFEADLQNFARKVKAGANLAITQYFFNADAYF
HFVERARQLGVEAPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GEEVITHLCERLLDGGAPGLHFYTLNQAEPTLKVIKNLTGR
>A0A3L6TKV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panicum miliaceum|TrEMBL
MKVIQKIQQAAADGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYTNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFMRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALAILMNL
GLIEESKVSRPLPWRPPTNVFRVKEDVRPIFWANRPKSYITRTLGWDRYPQGRWGDSRNP
SYGALTDHQFTRPRGRGKKLQEEWAVPLKSVEDISERFTNFCEGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLELFCAKEKLD
QLVEKIKAFPSLTCIAVNKDGKSFSNVPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWTRGWGCLFPEGDSSRELLEKVQKSYYLVSLVDNDYIHGDLFAAFKEI
>D9QBF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium pseudotuberculosis (strain C231)|TrEMBL
MSASHIPAAYQRSITEVLKMPSPGRIPFSVEFMPPRDAAAEQRLWKAAEAFHDLGTAFVS
VTYGAGGSSRERTMRVAHKLSKLPLTTLVHLTLVEHTEAELVEILNDYAAHGLSNLLALR
GDPPGNDPMAEWLATPGGLEYACELVELTKKNPETAHFQVGIASFPEGHYRAPTLEADTE
FTLEKLRAGAEFSITQMFFDIEHFLRLRDRLAKADSEHGNKPIIPGLMPITSIRSVQRQM
ELAGASLPRELERQLFDAAKGDEEAHKQDIRKVGIELTTQMAEKLIAEGVPDIHFMTMNY
VRATQEVLHNLGMAPAWGTEHGHDAVR
>A0A1S1U0U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium lividum|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRIKLSELQPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRASIRAVLADFKAAGVSRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLQAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKLGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A826E0Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni subsp. jejuni CG8486|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A6J1ZFR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinonyx jubatus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEASSGRFSVPPSISISHLTLPLRVLAACPLTLLPSTP
CSRNPAMVNEPRGDGGPTSRSEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRMES
GDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIAST
AVNYCGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYA
ADLVRHIRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADT
FFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIR
NYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHP
KRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPRE
ELLKMWGEELTGEESVFEVFACYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVN
RQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELR
VNYHIVDVKGEKITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQW
GKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A0P6X145|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolinea tardivitalis|TrEMBL
MGTMLHQKGVSFDACFDELNITNPSIVGEIHRDYIEAGSQIIQTNTFGANCYKLARFGLG
NRVKEINTAGVDLARRVIQGTFKEILIAGDIGPLGVRLAPYGRVQPEEARLAFTEQISAL
LDAGVDLLLIETMTDLQETRLAVKVARSLNQTIPIIASMTFTRDDRTLLGDSPSIVARTL
INEGADLTGVNCSGGPQQILRILRQMHAAIPNGKFSVMPNAGWPEQVGGRIMYAATPEYF
GDYAVLFHQNGARIIGGCCGTTPEHISAMKKALSKAVPLESAEPFEVSEQEPEFSRKEEA
LAPTKFGAKISAGKFVTAVEMDPPRGLATQKLIAGASLLAEAGVDVINVADSPMARMRMS
PWAVCSLIQQKVGIETVLHFPTRGRNLIRVQGDLLAAHALDVRNVFVVMGDPTSIGDYPD
AMDNYDLVPSGLIKLIKQGFNTGIDHSGANIGQPTNFFVGCALNLTPNSPADEIKNLARK
IKAGADFALTQPVFQPEAAREFINRIKNEMGEFNLPILGGVLPLANTRHANFLDQEVPGI
IIPPSVLERMRKAGEKSSEEGVKIAVELIEELRPLINGAYIMPAFNRYDLVAEVVEAIKE
>A0A671QEP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus anshuiensis|TrEMBL
NHVSTMGRNMVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMK
RRIESGDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPSGDPGSDKETSSM
MIASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDG
GFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLF
FRAETFLRFVKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDN
DAAIRSYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWA
VSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKS
KSPKEALLQMWGEELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDALAPETNLLKDE
LEKVNRRGILTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLK
KYEPRVNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFAL
WIEQWVKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFALLDSPRATQ
EEGSQS
>A0A7J8FAC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Molossus molossus|TrEMBL
MVNEPRGNGGPNPRSEGIGSSKGISGCSSPGLDPKRHERLREKMKRRMESGDKWFSLEFF
PPRNTQGAGSLISEFDQMGAGGPLFIDVTWRPTGDPGSDKETSSMTIASTAVHYCGLETM
LHMTCCCQSQEEITGHLRKAKQLGLKNILALRGDPLGDHWEEEEGGFHYAVDLVKHIRKE
FGDYFDICVAGYPAGHPDAESFAADLKYLKEKVLAGADFIITQLFFEADTFFRFLKACSE
IGITCPILPGIFPIQGYHSLQQLVKLSKLEVPQRIKDVIEPIKGDDEAICNYGIELAVGL
CRELLASGLVPGLHFYTLNRRMATTEVLKRLGMWAEGPRRPLPWAVSAHPKRWEESVRPI
FWASRPKSYIYRTQEWDEFPSGRWGSSSSPAFGELKDYHLFYLRSKAPRGQLLKMWGEEL
TSEESVFDVFVHYLSGEPNQNGCRVTCLPWNDEPLAAETSLMKEELLRANRRGILTINSQ
PNVNGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRKTVEALLQVLKKYESRVTYHIVDVKG
ENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFTLWAEQWGKLYDEESPS
RMIIQDIHDNYFLINLVDNEFPLDNCLWQVVEDTFELLNRPTSQ
>A0A7G7RU40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. B11D7D|TrEMBL
MSQQRRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTVNTVLQLD
GDVKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNLEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVGRVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRVFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWKNLDLKR
>A0A8B5Z4D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas vasicola|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
SALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A543AAP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides albertanoniae|TrEMBL
MDLQQRISDRAGEILLFAVTPPRVTTAPERVQQIAEVTLERIKPLDLDGLVLYDIDDESD
RNPEERPFPFVRTLDPAAFLERNLVGLDVPAIVYRATGKYDEPALRDWVKTQDPARALSV
FVGASSGEKRVATSLRRAQEIRQETNPDLLLGAVAIPERHTAKGDEHLRLIAKQEAGCSY
FVTQVVYDVNAAKNLVSDYGYECRARGIEPVPIIFTFSVCGSMKTLEFLRWLGVDVPNWI
ENELRQAADTLDASLEQAEATALELMAFCRQLGVPFGINIESVSIRKVEIEASVRLAERL
RGKLER
>A0A558NP52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassolituus sp. C2-1|TrEMBL
MTTLSFEFFPTQTDEGTSKLLAVRDELAAFDPEFFSVTYGAGGSTRDRTFAMVEAIQQRG
IAAAPHLSCVGDSTADLRDLLQRYQALGIKRIVTLRGDLPSGSGLASSELRYANELVEFI
RKETGDHFTLEVAAYPEMHPQASSFEKDLQNFVRKVKAGADSAITQYFFNADSYFHFVDR
VRAMGVDIPIIPGIMPITNYSKLARFSDSCGAEIPRWIRKQLEAYGDDSDSIVKFGEEVV
TDMCRRLLDGGAPGLHFYTLNQAKPSLAVWKNLV
>D5BW56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosococcus halophilus (strain Nc4)|TrEMBL
MHSQRKYPLTFSCEFFPPKGNEGASKLRRTRKKLALLHPRYYSVTFGAGGSTRDRTFETI
LEIQAEAKKSGIDAAPHLSCVGSTRGNIREILKAYQQHGVKRLVTLRGDLPSGMVDPGDF
HYANQLVEFIRAETDDYFYIEVAAYPEVHPQARSAQADLMNFKRKVEAGANSAITQYFYN
IDAYLRFVDRCESVGIDLPIVPGIMPINNYVQLARFSDACGAEIPRWLRKRLEEFHDPAA
MSAFALDVVSDLCHRLLEAGAPGLHFYTLNRAGPTLAIWDNLGLEAKPADLPTAAKT
>A0A177DTY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria alternata|TrEMBL
MERITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCIGVAAYPEGHSDQSHPQHQDPQFDL
PSLIEKTKAGADFIMTQLFYDVEAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTTLSHAKLPSDMLARLDAVKSDDELVKQEGVKIMDEMVEHIKARPDTCRRGFHFYTLNL
EKAVSHIVEDTHLIPSTIDDNDDVIVETTPAINLEPPPNGFVPHRRRSSAVNSGPRNRVI
ISHSSAAKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKDDISKLFRRHIEGDLEAIPWSEQSLSP
ETLTISKQLLALNAKGWWTVASQPAVNGVKSTDPVFGWGPKNGYVFQKPFVEFFIPASEF
AALKPKLDAHEQVTYFAGNAAGEFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIFQEWQRIYPPRSASSTLLGALRRDYWLVNVIWGDFVQGEGLWEFLEQ
>A0A5J6ZEI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MSFLKNKYHKDIIDQKLNNLNKKMKYSFEFFPPKNIDSENKLFNSVIKLNELKPFFFSVT
YGANSGEREKTYKIVKKIHEKTGVITAPHLTCVDSTTLELEKIAKFYWENGVRSIFALRG
DSNDKYHLHEMYACDLVILLKKIADFDISVAAYPETHPESTNSKSDILNLKKKIDAGANR
AITQFFFNTESYLRFRDNCIKNNINVEIIPGILPIYNFEQLKRFSKMTNVSIPYWMFEIF
DTLTDDLVAQKVIGASIVIDIIKNLSEEGVKNFHFYTLNQSDIVYSICRLFGL
>A0A1U7I8Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phormidium ambiguum IAM M-71|TrEMBL
MHSTPYPKPLNTFRNAVKNGEFLITAEVSPPKGGDPTSMLKMAQLLKGRVHAVNITDGSR
AVLRMCPLAASVILLQHGIEPICQVACRDRNRIGLQADLMGANALGIRNILALTGDPVKA
GDHPNCKPVFDLESVRLLQLIDKMNHGFDWNDKPLTDGATDLFVGAAVDPQSHSWSGLQR
RFERKLQAGAQFFQSQLIADFDKLEKFMNQIASGSNKPILAGIFLIKSAKNAEFLNRCVP
GIEIPQSIIDRLAAAKDPLREGMKIAAEQVQMAKQICHGVHLMAIKREDLIPEILDMAGI
SSIDNSI
>A0A0P6XL89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ornatilinea apprima|TrEMBL
MKIADLLKTYKTIFSFEFFPARTPEASEELYQTMTELIPLQPSHVSVTYGAGGSTRELTH
NLVLRLHNSAQLTVMPHLTCVGTTRDEVFEILTRYNDAGIENIMALRGDPPKGAEERAIP
AGEGFPYAADLVAFIKQHFPQLSVGVAGFTEGHPATPNRLKEIEYLKAKVDAGADFIVTQ
LFFDNRDFYDYCERCQLAGIQVPVIAGIMPIISKRNMLRMAELAAGVRYPARLLRALARA
EDDEDFAKIGRHWATEQVLDLLDHDVRGVHFYTLNKSRSTMQIYDALNLRKVMHSPENRF
>A0A2H9PU31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon CG_4_10_14_0_2_um_filter_33_10|TrEMBL
MRVTGIIKQKKWEIISVEIEPPSVDEGIEKVYEILNPLVKKGICYINITNHAEKIEKNGD
ESLSFQIERPGTIGVAGVIKEKYREKGVIPVPHIICTGLTRSDIERTLIDLNYLGIENVM
ALRGDPPKLNGNFMEFKPKENGPSYAKDLIKQIADLREGIYTGTKKKTKIDFCIGAACYP
EGYYKSQALDENINWTKAKVDAGADYLVTQLFFDNNYYLRFIEEAENAKIKVPIIPGIFP
ISLYAHLEKLPEVFGCSIPKEIIDKVEKYKYDEEDIKKVGIEWCVKQCLNLLEKGAPSLH
FFANRGAPIEEIIKGVYNPK
>A0A7W0F784|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MANFLNNNVPGIRVPQSLIDELKAAGKEKALDTGMNITARHIKQLKEEKICDGVHIMAIG
MEDKVPVIMEKAGLL
>A0A3A6PQ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus pinisoli|TrEMBL
MGAEQLRRPNLREALAERILVGDGAMGTYLYQMGFPVGVSYEEFNVLKPEVIESVHRHYY
EAGARLIETNTYSANLEKLSKHGLEDEMEAINRAGVRIARSAVGPDAYVVGSIGSIRDGK
RKNLRTKRVINAYEKQMKVLVEEGVDGLLFETFYDLEEMKLAVRIARELTDIPVICQFAV
EDAGRTADGITLADAFNQLQALGADVVGFNCRSGPNGIMRSMDSISAPVALPFSVYPNAG
IPDYVDGKYTYSAGPEYFAECARKFADRGARIIGGCCGTTPEHVAAMAASLANYVPQPGA
AAAAKRQSELVRENTPKPAEHASYGDIHQEPTLVDLVKERHTVIVELDPPRDLDIRKFME
GAAALREARADAVTMADNSLAVTRMSNIALAALLQERLDIRPLVHIAARDRNLIGTQSHM
MGLDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGVAFSGKPLKQKA
KFVVGAAFNPNVKHLDKAVQRLERKIASGADYIMTQPVYDTGLIERIAESTKHLSVPVFI
GIMPLANGRNAEYLHNEVPGIQLSDDVRARMAGLEGPEGRAEGVKIAKELLDCALQHFNG
IYLITPFMFYDMAVQLTEYVWEKTKR
>A0A2W6CHP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MDAPQPHTVLAELLASQVVVCDGAMGTMLHTAGVPLDRSLPELNLSRPALVRDLHAAYVS
AGARILQTNTFGANRLRLAAAGLEDSVSEINIAGARLAREAAQRAGHQVLVAGSVGPAVS
APAVRRVPASDRAQTLREQIAALCDWVDLLILETFGDLESLVQAVGVAASESDLPVVAQL
TFGDDGRTLRGEDPAVAAAVLSELRVTAIGANCTVGPAVLLDVVAELVRATDLPVSVQPN
AGLPQRLGSQVRYARNAAYFGQAAQRFVAAGATLVGGCCGTTPAHVRAISQAIAALPPVR
RSPISRTATPPATPGREVPPAPGWPAHWAGELVVAAGLPAPNGPQVSQFLQRATTLRAAG
AGVLAIIEAAPPAARISPVGAAVVVSERVGSAVLLPVESADRNLAALQADMLGAHALGLR
MVVCRTGSVRVSGDYPSAGSGSPWDVDSVGLVSMLAALNEGIDWRGVPIAERTRFVIGAA
LDTAASDLAHELDRVEAKLHAGAHFLVTDVIYDVEAASRVLGALRARGVALPVLATLAPF
EDVQTLQRLSYEMPEVSIPLSVLAAARRNRDSPEQTIEQAVGAVEKLRHLISGVVVHVPS
GMDELAAQLVNALTQLRDKL
>A0A7C1S4P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
NVTDNQAAVMRISSLAGCQLCLQNGLEPVLQMTCRDRNRIGLQADLLGASVLGIKTVLCL
TGDHVNAGDHKQAKSVYDVESVQLLKIVNGMNNGFDMSGNELQGATDFYPGAVVTPESVP
LEPQLVKFEKKVEAGAKFFQTQAIYNMDKFKDFMKYARQFPVKILAGIVVLKSAGMANFM
NKNVPGIMVPQDLIDEMKAAGKEKALDTGLNIAARHIRQLKEEKICDGVHIMAIGMEDKV
PEIMERAGLL
>A0A822J1D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon|TrEMBL
MITAEISPPKGTDTSRMLRDAALLKGIADAVNVTDNQRAVMRMSPLAACSILQGKGFETI
MHITCRDRNRLALQSELIGASALGIRNVLVMSGDHPSKGDHEGAKPVYDLDSVQLLGMIQ
ELNRGVDLSGNKLDGKTDFCMGAVTNTELNEAGLIKLKKKIKTGASFLQTQAVFDVKRFS
EFIEKKSEIELKQSKQIKIIAGIIPLRSQRSALFLNKVPGIRVPDDMIKQIKDAKYPEVE
GMRITSDIIKELRTLCDGVHIMPVGNHEHTKKLLEMAGLI
>A0A532ULT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium (candidate division B38) B3_B38|TrEMBL
MKENILNRLEKEVLLCDGAMGTLLNSKGVPYDKCREEQNLVNPELVRTIHQEYIDAGAQI
IETNTFRANRIKLRAFGLEDMIEEINKAAVTIAREAAGKEVYVAGSVGPLGVLAKPYGHL
TVEEISQLFQEQISYLVEAGVDLLMIETISSLLEAVEAISAAKKVSPTAPVVCMMSFLED
GKTKFGDEMINSLNKVKEAGADIVGVNCTIGPKETYDLARIFIPQVDAKISIMPNAGYPT
IVQGKTIFLSSPEYLKEYASLFVELGANIVGSCCGTTPEHTRAMAPQVRGKRPARGVSTS
PTITPVEGAAEISKVAVAVEARRFTEKLIQGKFAITVEVDPPKGSDYNKMLEGAEMLKSL
GVDALNISDNPMARVRMSSIALAHLLQEEVGMQTILHFTCRDRNLLGLQSELIGASALGI
TAILALTGDPSSIGDFPKATSVFDVDSIGLVKIIKGLNNGKDLANNPIGRPTYFKIGVAV
KPAAEGLELEIQRLEEKVKSGADFAQSQPIYDIEVVEHFRKKTAHLRLPLLVGILPLRSY
RHAQFLHNEVPGITIPKNILKRMQKSTPEEEMREGLKIACEFVRQVKGLIDGFLFIPPFD
KYHLVEEMIRAL
>A0A538RKX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSREPRRLKDVLDQGQFAVTIEYNPPKGTNISGVLENAKRLVGRVHGVNVTDNTAAIVRA
GSLPVCRLLYELGHDPVMQMTCRDRNRIAMQSDLMGASMLGIHNILCLTGDYPTVGDHKE
AKPVYDLDSVEVMQLVQGLNNGRDFMGNKLDGATQFTIGAAVTPEADPLGPMLAKFEVKV
KAGAQFFQTQAIYHPEQFASFMKAVRPFKVKVLAGILVLRNAKMAEFMNANIPGVSVPQE
MIDELRAAGPERAEDVGVNMAVRTIKAVRPHCDGVHIMAIKATHRLADIITKAEVG
>X0QX37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. JCM 18903|TrEMBL
MTKPAFSFEFFPAKTELGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRNRTLDIVQALCA
RGDTDIAPHISCIGDDKAEIAELLDLYKDLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREYSGDHFHIEVAAYPEMHPQARSFAFDVDNLVNKYQAGANASITQFFYNADSYLYLR
DTLERRGIDTIAQPLIAGIMPITNSSNLVRFADSCGADIPRYVRKQLSDFGDDRKAIREF
GFDVVYRLCERLIAEAYLPCIFIA
>A0A081NIS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endozoicomonas numazuensis|TrEMBL
MTSNEKKLPISFEFFPTKTEEGAKKLDQTAIELSKCQPEFFSVTYGAGGSTRDRTLDTVL
SVRSCTDVSTAPHLSCVGDSKTQLKALLEQYKRQGINRIVALRGDLPSGMGRSNGELQYA
NELVEFIRAETGDYFHLEVAAYPEAHPQAQSFETDLANFKRKVDAGASSAITQYFFNADS
YFHFVDRAADLGVDLPIIPGIMPITNYTRLARFSDACGAEIPRWIRKQLEAYGDDIESIK
KFGEEVITSLCERLIEQGVPGLHFYALNQAAPSRTICQNLKLV
>A0A4D7DNM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. EMRT-2|TrEMBL
MATPLIHPNWDKAPDGITDGFSLEMTAKDEASLRDAAPLIPADTPIAVTFLPGEDVAARV
AATVAVRELGFEPMPHFSARRILSEDDFEGYLKAVVEQAGVERCFIVAGDPPEPQGPYFD
TSALIATGAFERAGIKAIGVGGHPEGHPNMTVAECWAVLEKKVAEIERRGMAPLIVTQFG
FDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVTN
LLGSAGPDKLVNAFAQGLGPEHGRVRLHFYPFGGLVKTLEWIHEYNRKHGI
>S4PP07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus otakiensis DSM 19908 = JCM 15040|TrEMBL
MSLTALFKTKTVFSLEVFPPKKSSPTDAILPTLKRLQSINPDFISVTLGAGGTEHCDGTV
EIANIIQNKLNIPAISHVPGLYQTKSEVLALLDRLDSINVKNILALRGDKIPGKEPAGDF
NHANELVQFVHEQRPDFSIASACYPNCHTEAPDFVDDITHLKEKVDAGADHLISQLFFDN
QAFYDFKEKTEIAGIHVPIEAGIMPCTNKNQIERITQISGVPIPKKFAAIMDRYQNSEEA
MLDAGIAFAVDQIIDLVSQGVDGIHLYTMNKSKIAKRIWDETKSVFAAADLAKQTANQ
>A0A034T961|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edwardsiella piscicida|TrEMBL
MSFFHASQHDALNQSLAELQGRIQVSFEFFPPRSQEMEQTLWRSIDRLSTLRPSFISVTY
GANSGERDRTHGVIKGIKERTGLEAAPHLTCVDVSREALRGIARDYWNSGIRHIVALRGD
LPAEGGRPEMYASDLVALLREEADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGASRA
ITQFFFDVESYLRFRDRCAAAGIDAEIVPGILPVSNFRQLQRFAALTNVRVPQWMLAMFD
GLDADAETRKLVGANIAMDMVKLLSREGVKDFHFYTLNRAELSYAICHTLGVRPQRDVA
>A0A1E7GJ12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium S5133MH15|TrEMBL
MAVSSECGPPRSSDPAHIIEKGHLIKNHVDCINITDNQTSVTRLCSLAACIHLKQEGLEP
VLQMVVRDRNRIALQSDILGAASHGIHSMLCLSGDHQRFGDSPEGQNVFDIDSMQLLQTV
RYMRDEGKFLGGDAIKVPPNMFVGAAANPFADPFEIRVPRLAKKIAAGAEFIQTQCVYNL
DKFELWMKGVVERGLHEKVFIMPGITPMRSVGMAKYMARAVPGMDVPKELIDRLSGVPKD
KQSEEGITIAVEAMERLKECTGVAGFHIMAIEWEEKVPEMVERAGFYPRPEFD
>D5XC44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermincola potens (strain JR)|TrEMBL
MQNRFKESLLDKNTMSVTWELVPGRGAREKSQEEAIAAAEQAAKGGRIHALTLTDNPGGN
PAILADALAKEVLAKGIEPLVHFTCKDKNRNQIESQLYALDRAGIRNLLVMTGDYTVTGY
KGRPKPVFDLDPIHVLGLIGEMNKGLEYQGFKGTIKHQPSDFFAGAAASQFKATEAEQML
QYYKLKKKIEAGAQFIVTQLGYDARKFHEIIQFIRLNGWDIPVVGNIYILPLGTAKVMNK
NRIPGCVVTDKLVADLEREAQAPDKGKEARLLRAAKMYAFMKGMGYNGVHIGGHGMKYED
VEFIIDKGEELSKNWMDFIHEFDYPQPNGFYYYEKDEKTGLNTTTPTNRKGRPLDAPVEF
TYRLSKFMHNLMLEPGTPLWGPMTAVAKAVDGTSMEKKYHKFEHMIKVGLFDCKDCGDCA
LMDVAYVCPMSQCPKNQRNGACGGSFEGWCEVYPGKKKCAWVRAYARLKNSGKEEQLSKE
VIPPANWDFHQTSSWLNFYLGRDHTAKKFGIEPYVKKK
>A0A1R1YRM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium culicis|TrEMBL
MLKLNPLFIDVTWRWGGKSKDLTQEICINSQDVYGMESNMHMTCVGTKIDQINAVLKTAK
KNNLKNILALRGDLPLSSNISSDSSKNQTLLNSSDTGFVSDSSCDSPVILSNNSSSEDLV
SQTSLKLNSKMRLTNEFQSAEQLVKHIRNEFADYFCISVAGYPEGCVDKSHVETDIHILK
RKVDAGADFVVSQLFYDIPVYMDWVKRCKDIGINVPIVPGIMPIQNYSGFEKMVKMCNIK
VPEEIWTSLNSCKGDDLAVKDFGIQYSIYMIKTLVSSGIKGFHFYTLNLERSTQLVLEGL
ELVPLVKQPTINSIAENNNSNLKYVTSGFFDKLCAFNRQTKDLPWQPSPIGKRATENVRP
IFWHNNTSSYIDRTKNWDEFPNGRWGDSRSPAFGELNYGQVWTYTKSQVINLWGTPTSVQ
DLVDLFTRYCQNKLSSLPWSDTELMLESNEIKPLLESLNKAGYLTINSQPSCNGVTSTNL
VHGWGPKNGFVYKKAYIEFFIEPTKCEKLIKFLSEFNAESSESPMITYLAIRKDSQLKSN
WDIAKPNAVSWGVFPGCEIIQPTIVDADSFIAWKDEAFDYFQLWSNSYGHNQKYAETTSL
LNHISDTWYLMNLVDNNYTRSAEFMYNMLLSIGE
>A0A084JCX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sulfidigenes|TrEMBL
MHIKELFKEKEVVFSFEIFPPKPTSSIETVYDTLEGLQGLNPDYISITYGAGGSVNNNRT
CELSSLVKNKYGIEALAHLTCIGSTKSEINGILESLNENGIENILALRGDVSEGNPSVGE
FNNSQELINHIKETKEFGIAAACYPEGHIESRDIEREIEILKLKENAGAEYLISQLFFDN
NYFYKFLNSVEKSSIEVPIQAGIMPVTNKKQVERIVSLCGANLPSKFIKIINRYEHDKDA
LRDAGIAYALEQIVDLVSTGVRGIHLYTMNNPYIAKRITNSIGSILNSINKRQVI
>A0A0K3BIJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kibdelosporangium sp. MJ126-NF4|TrEMBL
MTSVLERINVGRATFSVEFMPPRDDADEQILWRSIRQLEGLDPAFVSVTYGAGGSRRDRT
IRTTGRVARETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVHNVLALRGDPPGNPMGEWV
KHPQGLSYAEDLVRLVRELGDFCVGVAAFPYGHPRCADVDTDAERLVQKFRAGADFALGQ
LCHSAEDFLRLRDRVAAKGSDAPILPGVMPLTTPKMLGKTVELSGAPVPPRVAARLEPLV
DDPKAFRAEGIDVVTEMCQQLLAEGVDVLHFYTFNRAKATKEVLGRLGLVPSRTA
>J6HQJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptoanaerobacter stomatis|TrEMBL
MKISDILSKNKVNLSFEVFPPKSDVALGAVLDTVRDIADLKPAFCSVTYGANGGTSGNTV
KIASYIENELNVCALAHLTCVLSSKEDIDEKLQKLKEHNIDNILALRGDIIDEEAFKNKK
DLIHSSELMSYIKDNYDFCIGGACYPEGHLESKSKDEDVEYLKLKQDLGADFLTTQMFFD
NNIFYNFMYKLRNKNVNIPIIPGIMPVTNVTQLKRIKQLSGAQIPPKFLSIADKFKDDVP
AMKQAGIIYACNQIIDLISNGINHIHVYTMNDSDIAKRISDNLSYILEK
>A0A1C3VBB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium multihospitium|TrEMBL
MSSRSESRSDGIRISFEFFPPKSEEAEQQLWNTVEELSDWDAEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLAAGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVQALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRAAGIKIPVVPGIMPIQNLTQLKRFAGACGTNIPTWLDERFDGLDE
DIEERARVAAEVAAEQIQDLMRRGIHEFHLYTMNRSTLVSAVLERLGLERKVDARAGAAA
>A0A0B4XJH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax pacificus W11-5|TrEMBL
MTGKRISFEFFPPKTAEGLDKLLGVQQKLLVKNPEFFSCTYGAGGSTRDNTINTVNRLRA
QHADTAPHLSCIGQGRDELVELINHYRDSGVTRIVALRGDLPSGMGYAQGELKYADDLVA
LIREISGDHFTLEVAAYPEMHPQARSFDDDIEHFKRKIDAGANHGITQYFYNADAYGFYL
DALQKKGCTAPVYPGIMPILNVANLLRFSSTCGADIPRWLASKLNDIKDDDAAVKAFGTE
IVTRLCERLLAMGAPGLHFYTMNQAGPTLKVLDNLGL
>A0A2S6UU19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha2_Bin1|TrEMBL
MTKLNQLKPIINRLITGEKPGVSFEFFPPKSKEMEQTLWSSIDRLSNFSSNFVSVTYGAG
GSTRERTHKTIKKIIENTNLTPAAHLTCVGASKLSINEVANSYWDLGVRKIVALRGDPPE
QTKKYSPHPEGYINAADLVDGLKKIANFDIFVACYPEIHTESKNFEDDLDNLKKKIDSGA
TSAITQLFFDDEIFLRWLEKVRSAGINIPIIPGIMPITNFLSTVKFCKICGASIPSWLKS
LFYSLDDDQETRKLVGAVVAAEQCRRLQAEGITDLHFYTLNRADLTYAICHILGLTQKSI
IK
>A0A1C4LKM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DfronAA-171|TrEMBL
MASGTASTWTSEHPTVAEVLASGKRSYSFEFWAPKTPKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRTGTVRATQAIAENTTLVPVAHLTAVEHSVAELRHMIGQYADGGVRNILAVR
GDPPGDPLGDWVAREDGLTYAAELVRLIKESGNFCVGVAAFPDMHPRSENWDSDVRYFVD
KCRAGADYAITQMFFDPASYLRLRDRLSAAGCETPVIPEVMPVTSVRQLERLSRLSTAVF
PETVKERMLAAKDDPAAVRSLGIEFATEFCARLLAEDVPGLHFITLNNSTATLEIHENLG
LPHHRP
>A0A807MPX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium ammoniagenes|TrEMBL
MVPRMSASAPLDYLELDSAGNTLQPDEGKAPGRTALSFEVIPPRHDADSAKTENLLQVLS
GYNPDYIAVTSSKRSGWLEGTAKFIAQISSTTAMRPLAHLACTAGNKQELTEWINVLVDA
GVRGFLALRGDLEPGQRELPDGYLQHGDELVRLIRQLESQQAARFAAGRLAVGVACYPNG
HAESAHDDEDFDVLLSKQRSGADLAITQLFFDAEDYLKFAQRARLAGTRMPLIPGIMPIT
SLKRAQRMGELSGLEVPPKLIDKLSRARGPDEEYAIGMAHTVELAQAVLAGGAGCLHIYT
HNNASITQELLTAIGIKSFKEKP
>A0A511J843|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas composti|TrEMBL
MSRPPGAHAAPASVDRPTVSFELFPPRNPDAAPRTWETVRAIEQVHPDFVSVTYGAAGKT
RETSRVFVSRLLQETNLDPIAHLTCVGTSRADTIEIVEEFLDEGVRSFLALRGDPPLDQP
DWRPHPEGLHTAGDLVGLLREIETRRCAGSASQAVRARVRPLSIAVAAFPRGNAGTGGTR
AQDVASLLAKQEAGADFAITQVVFDAESYLELVAEARDAGVVIPIIPGIIPSTDPGRLLR
VQELTGVLVPTTLLEELGSASDDLDRHRRGVRAGIDLIKGVLDGGAPGVHVYTYNQHHAA
LDLLDGAGLRGSGARSSAPAAVLA
>A0A432UTN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiothrix sp|TrEMBL
MESQQKLQKSFSFEFFPPRTEKGIENLRNTRQKLAELKPRFFSVTFGAGGSTQDRTLETV
LEIQGESELEAAPHLSCIGSTQESIREILTTYVDNNVKHIIALRGDLPSGLGAAGEFRYA
NELVSFIRQETGDHFHIEVAAYPEFHPQTSNAQTDLDNFQHKVEAGADSAITQYFYNPDA
YFRFVESCEKRGLKIPLVPGIMPISNFTQLARFSDACGAEIPRWMRKRFEAYGDDLESIQ
SFGEEVITRLCETLLAQGAPGLHFYTLNKSEPSTTIWRNLGL
>A0A0Q8MKW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium sp. Root700|TrEMBL
MSPHETALGPVARAGAGTAPRPSVSFEFSPPKTPEAEASLWEAIRRLEPLNPSFVSVTYG
AGGSTRDRTHRTVVRMLKETNLKPAAHLTCVEASKAEVDEVVQAYWDAGIRHIVALRGDP
PGNIGGVYTPRADGYLNATELTAGIKAVAPFEVSVSLYPQIHPESPSIDHDIDVLKAKID
AGATRAITQFFYDIDAYLFFMDKLRKAGVTIPVSPGIMPVSNYKGLKKMAGPVGITLPSW
LANLFEGLDKDPETRKLIACSVATEMCVRLAEEGYSDFHFYTLNRADLVYAICRVLGVRE
NGPEPVEAAA
>A0A662ZGD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminobacter amylophilus|TrEMBL
MQVAQIFKQKKPVVSFEIFPPKRDEALKSIDETLGILTELKPDFISVTFGAGGSVTNSKT
VEIASKIKKNFGIEAVAHLTCLNYSKDEIIEMVNNLKANDIDNILALRGDHNPNLAPKND
FMHASDLITFVKQHSDLGISAACYPEGHPEAQSLSEDVINLKRKVDAGAQHLVSQLFFDN
DIFYRFIELCKVAGINVPIEAGIMPVINKAQIERMVGLCGASLPDNLKRMLDKFADNKEA
LFDAGIAFATNQIIDLLAAGVDGIHIYTMNNPKVAMKICDSIKNVIASNRA
>A0A7W2H5B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MSLFGSKEEDGAQRQVRWNLIDSARLEVIPLKNLDSQLQYLPEGSSVSVTASPAKTLEDT
WILSRKLSERGFKPVPHLAARMLTSETQLVSLISQLPEVGASELFLVGGDAPDPFGPFVD
SIQVLESILALDHGLDHIGVTAYPDGHSFINETTLSESLHAKQALLESAGLSGHASTQMC
FDPAAIRGWLQRERDAGLTIPIRLGIPGAVDRAKLLSIGARLGVGASLRFLKKNKSTVTR
LFAPGGYNPNKLLRPLTGVVEPLGIEGLHIFTFNQIEKTEMWRRANLS
>A0A6P6PYX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carassius auratus|TrEMBL
MVNQRVDIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKISAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIVTQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGI
HQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMSEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPQETQEE
>A0A807ALH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium ciceri biovar biserrulae|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A7W7N2C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas bullata|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNQNAVNVSFEFFPPKSDEAEANLWSAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIEGYKAIGVDH
IVALRGDPPGGDGIGGAYVPRTDGYANATELSRAINSVGGFDITVGAYPEKHPESPSIDH
DIDVLKAKVDAGATRAVSQFFFDIEAFLRFRDRVRAAGVTIPLIPGIMPVSNFKGLSRMS
AACGAAIPDWLAAHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVREARADA
>A0A836KXI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porcisia hertigi|TrEMBL
MPGFISDAVIAEDTKKWYTSYEFYPPRSEKAEETMMNVLIPSIMRQSPVFLDLTWGAGGR
SSDTTMRLCKVLQEKYPDTPVNMHITCTNMPRGLIKEGLDFAKAHGIRNILALRGDPPQG
VEFQANPDGLTCAKELVQYIRATYGDFFCVSVAGYPEGHPSAIAKDGSISEEDYQKELIY
LKEKVDAGASLVVTQLFYDPSVYVKFVKRCREVDITVPILAGLLPITTYAGFERMVSLCR
TNVPDDVKKRVVELKENPEGLKKYGVEQCVQMIEYIRASDLDYHHLHFYTLNNSTQTFEV
LRRLNALVE
>A0A7X9SJ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium stationis|TrEMBL
MVPRMSASAPLDYLELDPAGHPRVENKEQAFSRTALSFEVIPPRHDADQAKIANLLQVLG
SYNPDYIAVTSSKRSGWLEGTAKFIEQISSTTTMRPLAHLACTAGDKRELISWINVLVDA
GVRGFLALRGDLEPGQTSLPEGYLQHGDELVRLIRQLEGEQAARFAAGRLAVAVACYPNG
HAESANDDEDFDVLLSKQRSGADLAITQLFFDAEDYLKFSQRAQLAGTKMPLIPGIMPIT
SLKRAQRMGELSGLEVPPKLIDKLSRARSPDEEYAIGMAHTVELAQAVIAAGAGCLHIYT
HNNADITQELLTAIGITANSTIKS
>A0A849YAX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiae bacterium|TrEMBL
APALAPASSVGSTLPEIARRRTLIVVEFDPPKTLARDRMIAASRALKEAGADFLTVADNS
LAVMRMSAPIASYLAWRETGLRSIVHFACRDRNLIGTQSDLMGMDALGLDHVLALTGDPS
KVGDTPGATSVYDLNSISLLDGIRAMNAGRSFGGRDLKRATRFVAGCSFNSNARNLEIQV
RRLERKVAAGAAFVMTQPIFDPALARATRDATAKFGIPVLVGVMPLLNARNAEFLHNEVP
GIAIPDAARARMRGKEGAAGLAEGLAIAREIAAEVLAHFGGIYLVTPLVRHELTAELTAA
VRGGHL
>A0A7S0WED0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ostreococcus mediterraneus|TrEMBL
MSLVDALKDPSRPVFLFGVTPPLDGADAAAYDDAARNFVSKSRGLAVDGYIVYDIQEEAG
RTPEPRPFPFRKLGDPGVYAASLKRASKGIESVVYKCVAETKSEEEFGSWLDDASRATRA
YNLVGGASSSQDYSGPTIARAAEMVKAIDKGCAFGGVTIAERHVKKGNEHETLCAKMDAG
AEWFISQAIYDADATIKLINDYGAECAKRGVAPKKIILTFAPCGREKTMRFIKWLGVSVP
EDVERDILESDAPVQKSVSILTAMCQKIIDETKASNVPLGVSVESVSIFKNEIQAAHDLF
RLTQAIMLDAYGADWAMTYALVGGKSVETTTTQTNTTDYAHGDNHDNALKDKIKNVLVPL
G
>A0A849Y7A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiae bacterium|TrEMBL
MTAHAREGGLRTRLESGRFCYGVELVTTRGFVPPEKPNAVVALGQRLAADPRVDWLSITD
NPGGNVMLPPDWLGRILGAGPKPIVLHLTCKDLNRNGLESAAWRYASEGFENILAMTGDY
PRKGFGGEATPVFDIDSVGLIQMLSAMNQGLPSPGKKGETAVLPKTNFYIGCAVSPFKRL
ERELMPQYYKLLRKIAAGARLIYTQVGYDMRKSHEVLLFLQNQGLTMPVIGNVYLLNRTV
AGLFHRGQVPGCVVSAALMELCERYGRGPDKGREFFFDLAAKQLAAFRSLGFAAGYLGGT
MKAETIEEIIDRAERFSLDEGKEFAKEIQFGQPDEFYLFERDPATGLGATGQINRAYLAS
LRSPHASQENGAAYRMSRFIHDKVFTPGTPGFRLMQRLYGWLEHHPSVARGLHRIEHAGK
ALWFGCRDCGDCSLPDTAYLCPLESCSKAARNGPCGGSRDGRCEMDDKECIWARAYERLK
GYGETEQMLDKKPVLYNAALRGTSAWSNTFLGRDHHAAAPPPSANKKKGESS
>A0A7Y3LMU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MTQISEMLKKGRTFSFEFFPPKNDEEQAQLVRVLHDLVPLSPSFVSVTYRGGRSSRKRTH
DLVAGLKQTTALIPMAHLICVDHTRLELAEILLDLRKAGVVNLMALGGDPPKGEDQKYGE
LTYAIELVELAQAIGGFSIGVAAQPQGHPDSSDMESDRRHLAEKLRKADFAITQFFFEVD
HYMALVDDLSALGVDKPVLPGILPIERLSSVGSIKTMGASVPPKMIEKLENAQNSSSKDP
TGAVKRAGIEMAVELCQKLLDKGCPGLHFYTLNRSTATREIYDALNLNPATSETPNSNF
>A0A1W9P2M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium 4484_213|TrEMBL
MNFQEKLDKGKFVITAEVTPPKGTNVQSTLSAVDSLKDKIDAINVTDMAGGVMRLGSLCL
SYLIKQRGGEPIFQITGSHRNRLALQSDILSASVLGIRNILVLSGDPPSYGDQKEAKPVF
DLDS
>A0A0D6JI22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Filomicrobium marinum|TrEMBL
MEPKSRLVGDGEIDVSFEFFPPKTEKMEETLWHCIHRLAPLRPEFVSVTYGAGGSTRERT
HTTVSRIIKETNLKPAAHLTCVDATKAEVDDVARDYWTSGVRHIVALRGDPASGVGDHYV
PTPGGYANAAALVSGLKSIAPFEISVAGYPECHPESANLDADIENLKAKVDAGADRIITQ
FVFDGDYYLRFLERARAAGIWVPITPGVIPIHNFAQVSGFARKTGATIPAWIERRFEGLE
NDPKTSHLVASAVATEQVLGLVDEGVKSFHFYTLNRADLVYAICHLLGLRPAPVDSAKAK
ANAA
>A0A1G5HEN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. INlla14|TrEMBL
MTIKEIFQNKEVTLSFEVFPPKTDDGYEAVEKAAAEIAALRPDFMSVTYGAGGGTSKNTA
NIAADLQNKYNTPVLAHLTCVSSTREFVKDMITVYKEKGIENIMALRGDIPKEGRICYDY
DHATQLIYDIKSQDDSFCIGGACYPEGHVECARQSEDIEHLKEKVEAGCDFLTTQMFFDN
STLYQFLYRIREKGIDVPVVPGIMPITNARQVARSVALSGSTIPQKMKIMVDRFADDPQK
MKEAGIIYASDQIIDLISNGVSHIHVYSMNKPDIAAGIMRNLATIIR
>D6SM74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfonatronospira thiodismutans ASO3-1|TrEMBL
MGFREAVESGKFLITAEVGPGKGTDMHELLEDAEAIKDRIHAINVTDLQSSVMRLGSLAV
SHILADKGIEPIYQLTCRDRNRLALQSDLLSAWVLGIQNVLALTGDHPVLGDHPESKPVF
DCDSVSLLQMMQTLNGGHDMAGNELKGVPDFFPGAVVNPGADAGAGLEMQLIKLEKKIEA
GARYIQTQGVFELDSFEKFMKRVEGFNVPVMGGIIMLKSAGMAKFMNKNVAGISVPESQI
KAMTDTDDKVKTSVEIASHLVKGMKDICHGVHIMAIGWEKKIPMVLDEAGL
>A0A318E8G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium congolense|TrEMBL
MKIKNIFEEKEVVFSLEVFPPRPDVPIENIYQTLEELKDIDPDYISVTYGAGGGVKKNRT
CELSSIIKEKYDVEALAHLTCINSDQETLNKILARLESKNIENILALRGDKPVDGEALGD
YNYAYQLVEHINKHNDFGVAAACYPEGHLETESLDQDLEYLKQKVDRGVDYLISQMFFDN
SLFYKFRNKAEKKGINVPIEAGIMPVINKKQVGRIIELSDAYFPKKFQKILDKYEDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKVD
>A0A7Z7E515|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia hospita|TrEMBL
MNPIELSFEFFPPKTQEGLDKLRATRAELLPLKPKFVSVTFGAGGSTQQGTLDTVLDMAK
DGLEAAPHLSCIGSSRESLRAILNEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFRIEVAGYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DAHKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VADLCRRLVEAKVPGLHFYTLNGSAATKAICERLVG
>A0A7C2MR31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidilobales archaeon|TrEMBL
MMISFINLNMLLADILRVSMNTCPKKMINGPCGGYIGTLCEDRSLKCVWILAYFAASKRG
SLDKMFTLKLDPGFRVNSYRPVARRRRGAVDMTLSGRSFLVYEYTPKPYSGPLDIGDEIS
KLVGVYSGVDFVDNPGGYPIPSSLPYAVAAKSIYRDLHVSIQITARNRDRSQVVSDVLAA
SLAGLDAIVATTGDLQDGGKGVWDLDAPRIIYLARLVLDLGLDHMGRRVGIGGEPMAIAG
SININAEPLEPEILKIRVKIDAGAEFFITQPVVDIDRLYRFYRMARAILGNIDEIPIMIG
IIPITSRRIASFFENKVGIKIPEKILEILRREKIDRDAIIKANLDLIESNLKRISHNAFY
ISAFGDHSLGVEIGKVVRSIIG
>A0A679HN29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. KM1|TrEMBL
MEQEPKRLLEVLDRGQFAVTIEYNPPKGTNLTAVLDNAKTMVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQMTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKD
AKPVYDLDSVQVMQLVQGLNHGRDMAGHALDGATAFHIGAAVTPEADPVGPMLAKFEVKV
KAGARFFQTQAIYNPDQFAEFMKAVRPFKVKVLAGILVMRNAKMAEFMNANIPGVSVPQA
MIDELRAAGARSEDAGVEIAVRTIKAVQPHCDGVHIMAIKATHRLGEILTKAQLG
>A0A7C4Q923|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bellilinea caldifistulae|TrEMBL
MKDSKFLDLLQTNQRPLLSDGAMGTLLNQRGVSFERCFDELNLTDPALVAAIHREYIDAG
SQIIQTNTFGANRFKLAHHGLEHQVAEINAAAVELARRVVMASFKDVLIAGDVGPLGVRL
APFGRVQPEQARQVFAEQIAALIEAGVDLLIIETMTDLYEIREAISAARQINPHVPVVAS
MTFTRDDRTLLGDDPIKVARGIQEAGADVIGINCSGGPNQILRILKQMHAALPEARFSVM
PNAGWPEQVGGRIMYPASPEYFGEYALAFWQAGASLVGGCCGTTPAHISVMRQAIETRPL
EKFSNGFSLAVVEREEASQESQAPTQMAQKLMDGRFVVAVEMDPPRGLTTQKLLAGSSLL
AEAGADVINVADSPMARMRMSPWAVCRLIQEKVGIETVLHFPTRGRNLLRVQGDLLAAHA
LGVRNVFVVMGDPTAIGDYPDAMDNYDLVPSGLIKLIKQGFNAGVDHAGVDIGQPTSFFV
GCALNLTPSNPESELKNLRRKLNAGADFILTQPIYDLKPAVSFLERIKSEIEHFHTPLLV
GVLPLVSARHAAFLQHEVPGVNIPQEIHDRIAAAGERAAQTGIDIAFELIEQMANFAQGI
YLMPAFNRFDYAAEIIEKVRRLELPAEQTKFSQSG
>A0A1R4A9S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cuniculiplasma divulgatum|TrEMBL
MQISNFQSKQKILKSVEIVPKRNENIDDLLAAREIFSDIADMVTAPENQMGRPGIDPLMA
LYIMTHGTNVIAMPHVTPRDKNTLYISSQILTSEKLGINHFFVIGGDPISGNFGREVREM
DTNETIRHIRKFSREQERHKEAIIGAALNPYRNSEEVIVRSKIESGATLFISQMCYNSEP
FKKKWIRQRKFKLFLGFMPILKKSNIESLSKMGVLLPEGLKSIIANSENLRDTSLKLIDN
LVSDMKGYIDGVHIMPIGNNEIAKEIMEVL
>A0A7U6AFM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. YAU14A_MKIMI4_1|TrEMBL
MSMETGARARAFLDACSWEVSAKAVQALRAEAARIAPGTTISIPYLASEDDQARLAAARA
IRELGFQPMPHLSARRIGTQAALEHFIQRAVGEAGVERCLVIAGDLAAPAGPFADSTAII
ETGLLERAGIKVVAVGGHPETHPVMAAAQCWQVLQNKCQRIEAHGMAPWIITQFAFDAEI
VLAWLNALRTRGVAHPVLVGIPGPASVTRLVRYAAMCGVGASTAMLARYGISLGRLLGSA
GPDRFVDKLLAGMGDELGPVSPHLFPFGGIAPSLDWVQQYRRNARSG
>A0A0M1NY30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. FJAT-22058|TrEMBL
MNFRKELKERMLVGEGAMGTLLYSNGIDQCYEELNCTNPDQIESIHRAYLEAGADILQSN
TYGANFNKLKRYGLEDEVSRINRQGVILAKKAAKGKAYVFGTIGAQRSIRKSDLSMEEIK
RGFREQLYSLLMENPDGILLETFYDLEELETVLQIVKNETGLPIIANVSMHELGNLQNGI
HLNEAFLKLEQLGADVVGVNCRLGPHHMIRALEEVSLPKQASIAIYPNASLPDYVDGRLV
YKAVPEYFGSSALELREQGAAIIGGCCGTTPLHIQAVKHAIGSLAPVKEKFTKSREIEVI
EVNDRELELPLYEKAKTERTILVELDPPKKLGIESFMTGAEVLKKAGVDSITLADNSLAS
PRISNDALANLLKNQLNINPMVHITCRDRNLIGLQSHLMGLQTVGLNEILIITGDPSKIG
DFPGATSVYDLSSFDLISMVKQFNEGLSYSGQSLGQRANFKIAAAFNPNVKYLDKAVLRM
EKKIACGAQSFLTQPIYSVEQIEEVYEATKHLETPIFIGIMPLTSTRNAEFIHNEIPGIK
LPDNVRRAMALAGDDPVKSRIEGVNIARELVDAAREKFKGIYLITPFLRYEMTAELTKYI
RKVDSKQTSEVAVHE
>A0A6I1JHA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthobacteraceae bacterium|TrEMBL
MSSAYKPSRYVSRSRLKVSFEFFPPKTEEMEATLWESIERLAPLEPSFVSVTYGAGGSTR
ERTHATVARIIRETSLKPAAHLTCVAATKEQVNEVIRDYWSAGVRHIVALRGDPVGGVGT
KYESHPGGYEGSPELVAGIKAIGDFEVSVSAYPERHPESPSLDTDIDMLKRKVDAGATRA
ITQFFFDNDVYLRYLDRVRAAGITIPIVPGIVPVQNFKQTAGFAARTGASVPDWLARRFE
GLENDPATRKLIAAAVAAEQALDLVDRGVTEFHFYTMNRADLVYAVCHLLGMRPKDAATS
AVAA
>A0A8F9TLA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudochrobactrum sp. Wa41.01b-1|TrEMBL
MSSFGQQRRSESAHPIRVSFEFFPPKTEEMEDRLWETVTRLAPLNPAFVSVTYGAGGSTR
ERTNKTIARIIKETSITPAAHLTCVDATKEEVNSIVRSFASLGVTRFVALRGDPASGIGE
AYQPTPGGYQNGADLVAGLKSIANFDISVSAYPEKHPESPDFATDIEMLRRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIIPGVLPIHNFKQVANFSKRAGTRIPAWLADRFD
GLENDPQTHMLVSAALAAEQVNDLIERGVNDFHFYTMNRSDLAFAICHLLGVRAPVAA
>S0FSZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotignum phosphitoxidans DSM 13687|TrEMBL
MSEYVSDSRLERVLKAGHLGVTSECGPPRGSDPEEIKKKGMLIKDYVDAVNVTDNQTAMT
RMSSLAACVHLKLLGIEPVLQMVTRDRNRVALQSDILGAASFDISNMLCLSGDHQSFGDC
AQGQNVHDLDSMQLVQTVRYMRDEGKFLGGDDIKRPPRLFVGAAANPFADPFEIRVPRLA
KKIACGAEFIQTQCIYNIDKFKEWMRRASDRGLTEKVFIMAGMTPMKSVGMAKYMKNKVP
GMDVPDEIIQRLAGVEKKHQAQEGIQICVEHIQELKEVPGIAGFHIMAIEWEEKVPEIVE
KSGLYPRPEV
>A0A498HW02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malus domestica|TrEMBL
MKVIEKIQESLVDEKKVVFSFEFFPPKTEDGVENLLERMDRMVAHGPAFCDITWGAGGST
ADLTLDIANKMQNLICVESMMHLTCTNMPVDKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQIQGGFACALDLVTHIRAKYGDYFGVTVAGYPEAHPDAIAADGLASPEAYQSDLAYL
KRKVDAGADFIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPAEVTAALEPIKDNEEAVRLYGIHLGTEMCKKILASGIRTLHLYTLNMEKSALAILQN
LGLIEESKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWELYPHGRWGDSGN
PSYGALTDYQFMRPRARDKKLVEEWVVPLKSVEDICEKFKKFCLGKLKSSPWSELDGLQP
ETGIINESLGKINTKGFLTINSQPAVNGERSDSLSVGWGGPGGYVYQKAYLEFFCSKEKL
DALVEKCKALPSLTYMAVNKDGSWVSNTGQTAVNAVTWGVFRAREIIQPTVVDPASFIVW
KDEAFEIWSRGWARLYPEGDSSRKLLEEVQSSYYLVSLVDNDYIHGDVFAVFADV
>A0A7W6MV78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium taibaishanense|TrEMBL
MDKAVLDASGNSVADSQALLSDWSIEVTPRTAAKIGDFRELLPAGTRIYIAHVDGTAFAD
MASTAKRLNDEGFAVMPHLPARSFASVGELEEVLRTYRGEADVRQALLLAGGIAKPRGTL
ASSIDLIETGLFDKMGFTQLNIAGHPEGNRDIDADGGTAQVDAALRWKVDFASRTDAQLA
IVTQFAFDASVIVNWAERIAALQIGLPIHVGIAGPAKLQTLIKYAISCGVGPSLKVLQKR
ALDLRKLLMPYEPTEIVTQLCAYKAANPHSTISRLHLFPLGGIEPAARWIRDFRP
>A0A2T5AKZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia psychralcaliphila|TrEMBL
MDRIAGSTTPRVPFSVEFYPPRDEAAEERLWRAASVFSELGAAFVSVTYGAGGSTRDRTV
RVVERVVSETDLVPIAHLTAVGHTVAELREMIQMYADVGVTNILALRGDPPGDPLGDWTP
HPEGLHYAEELVRLIHEVGDFHVGVASFPEGHYRARDLDHDTEILLNKLRAGAEYSITQM
FWDVEDYLRLRDRLGAADPEQAAKPIIPGLMPVTSLRQVRRMVELSGCALPDGLSDRLRA
AAGDGPDEDRAAVREVGIEFATELCERLIGEGVPCLHFNTLNFSRATHEVLANLSMVPSP
GVGASRT
>A0A101D7J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter thermocopriae|TrEMBL
MLKNENLCTKLKKRKFVVTAEISTPKGVDITKTIEEARKLKGIVDALNITDCPMANMRMS
PIAVAHLLQDHLNIEAIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDDPSRGDTPQ
VKGVYDVDSIGLLKIISAFNRGYDYNGNKLDSPTEFCAGTTANPNDLRDEALEKLKVKIE
AGAEFIQTQPVYDEEILFKFIEKIKNFNVPLLIGILPLKSYKMAVNLNEKVPGIDIPEKV
LERLKDGGREEGINIAVEFIKRIRSEVAGIHIMPLGSTNVVLEIISRVDDLVCDFAENNV
QMN
>A0A521VTP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthobacteraceae bacterium|TrEMBL
MTVTTKPATLAAATALAAAFKDAPVRAPAVSFEFFPPRTEDMERVLWESVTRLAPLAPSF
VSVTYGAGGSTRERTHATIARILTETALTPAAHLTCVDATRAEVDEVIARYHEAGVRHIV
ALRGDPAAGLGAAYAPHPQGYRNAADLVAGIRRQYPDIEITVSAYPEKHPESATVEADID
MLKAKVDAGASRAITQFCFDNDLYFRYLDRVRARGITIPVVPGLLPVQNFKQASTFAERA
GASVPGWFARKFDGLDDDPTTRKLIAATVVAEQALDLRARGVDTFHFYTMNRADLVFAIC
HLLGVRPAHPHEAA
>A0A1R1JJK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MSLIPRGTPSFPGNISDDCSLEASVKDIAALTAAASRIPPGSTISIPYLPGQDDDARLAA
ARAVRGLGLEPMPHLSARRMASLAELEAFVTRAVAEAGVERCFVIAGDPSTPAGPFADSA
SLIETGVFERAGIKVVGVGGHPDGHPVMSAAQRWEVLERKCHGIGARGMSPLIVTQFGFD
ADIVLAWLEALRARGLEHPVRVGVPGPAGIAVLARYAALCGVGACASMWSKYGISLGKLF
GTAGPDVFVDRLAAGLTDAHGKVSLHFFPFGGIAQSVSWMERYRARSGQPGCAAASLP
>A0A3G2N4X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. LTJR-52|TrEMBL
MTRTTPNVSFEFFPTKTEAGHEKLLNTARQLAGYSPEFFSCTYGAGGSTRDRTLNTVLQL
DSEIRIPTAPHLSCVGDSKAELRDLLIRYREAGITRIVALRGDLPSGMGISGGELRYANE
LVSFIREETGDHFHIEVAAYPEVHPQARNFEADLANFVRKIKAGANGAITQYFFNADSYF
HFVDRACKLGADVPIIPGIMPITNYSSLARFSEACGAEIPRWIRKQLEAYADDVKSIQAF
GQEIVTDMCERLLAGGAPALHFYTLNQAAPSLAIWNNLGFKS
>A0A2N4X465|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. TH158|TrEMBL
MTLQPPLFADLAGDVSVSFEFFPPKSEKMEEQLWDAITQLAPLDPSFVSVTYGAGGSTRE
RTHATVARIVRETSLVPAAHLTCVAASKGEIAEIADQYWEAGVRHIVALRGDPPGTDQRF
APHPDGYASAAELVGGLASRHAFDISVAAYPEVHPEAVDANADLDNLKRKLDAGASRAIT
QFFFSPEAYFRFLDKVLAAGISAPILPGIMPVTNFAAIRRMSANTEIPGWMEAMFEGLDD
RPGPRALVAAVVAADMCRRLYEGGVRDFHFYTLNRAEQAYAVCHLLGLRPKETEA
>A0A077QFW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus bovienii str. Intermedium|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPSTTAMEQTLWNSIERLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKDKTGLDAAPHLTCIDANREELRNIAHDYWESGIRHIVALRGD
LPDSSGKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATMTNVRIPSWMTRMFE
GLDDDLESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A6L6B3Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRSLKSDGSKALTYSFEFFPPKDVEGEERLWAAMSQLESIAPDFISVTYGAGGSTRDRTI
RITSEITARTHIPTVAHLTCVGSSRAELLEILGKYRDAGIKSILALRGDPTGGPRAPWSA
THDGLNHADELVTLAAEFGGFTIGVAAFPDGHPSSRGDFNKDVEVLLEKEKRGATFATTQ
FFFSADKWKSLIDKLAAKGSSMPIIPGILPVTNVKQLNRMAELSGVPIPGHISDSFIKFE
SNPDDVRKLGVEIATELCNDLLEAGAPGLHFYTMNTSSATREIYSHIKDER
>A0A7K1DWH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSLLREKLEKTNDVVFTAEFPSVDGGGMASVEKNAARLAPWFDAVNATDNPAAHAHTSNT
TTAIAMKMHGLEPIMQIVCRDKNRLAIQSDMMGASLHGITNISLLTGDDVTAGDEPEARR
VFDVDSAQAINIARILATGKYLSGRKINPAPDFYLGAVENAAAPPFDYRIQRALKKYRAG
ASFLQLQICYHPERLEAFCKGVAEVAPDLKLIPTVVLIKGAKGLGFMNDKVPGIDVPDSM
LARVQNASDQSNEAYALTLELARHALSLPGVRGLHVTDFRHDDSLGNLMTDLGQTPRSSI
TNR
>A0A7X7PMD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTARLKAGSKLERLLAAGAFTVTAECGPPKSADGMVIADKAKLLVGSVDAVNITDNQTAV
ARICSLAASYLAQQNGCEAIMQMTCRDRNRLAMQADILGAAALGIKNILCLTGDHQSFGN
HPQTRGVFDLDAVQLVRMFKDMRDEKKFQCGEEMPTEPRLFIGCAENPFGDPFEFRALRL
KKKVEAGADFVQTQCIFNIPKFKQWMEHVRVLGLHQEVKILAGITPIKGAGMANYMKQSV
PGMDVPQEIVDRIAAKDKGAPQQEEGKALAVEMIKELAEVEGIAGIHVMAVEWEPVVPEI
VERAGLLPRPAVTE
>A0A7V9SFM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTGPSSIAPPPPEPPQSFLKQSGFGILTEVEPPRRPDIEHVRRQIEVLKPVTDAFLIPDN
HLGRATVSSVAVAHEVAYLGGRGIACLNARDRNLLGFRRDLLTAASYGVDHFLFVYGDAP
QEGRRTEDLTVRGMINEVRSFGEGPLFQGYSDFRIGTVAKVGRPLAWRTQADFVFVQVTY
SFERLLQWRESLDYAGRMYAGVLVLASARMARRINASIPDIQVPETIVDKLDDAEVGVDL
ACEQIERVRASGAFDGVHLIPVGRYREMAARLKTITTS
>A0A7K0TEG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSVLREKLENTSELVFTAEFPSIDGGGMESVVKNVARLAPWFDAVNATDNPAAHAHASNT
TTAIAMKMHGLEPIMQIVCRDKNRLAIQSDMMGASLHGISNISLLTGDDVTAGDEPEARR
VFDIDSAQAINIARIMASGTYLSGRKINPAPDFYIGAVENAAAPPFDYRIQRALKKHRAG
AQFLQLQICYHPDRLEAFCKGVAQVAPDLKLIPTVVLMKGARGLAFMNDKVPGIDVPADT
LSRVQNASDPSVEVNKLTLELAQHALSLPGVRGLHVTDFRHDETLDTFMSDLGRTPKRQG
>A0A1Y1L2P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photinus pyralis|TrEMBL
MEMLSAVIHRASITNEKIISIEICPKRKLDVDELNKLRPTFCSIVWHYDGSEIEHIPALV
LLKKLSIHSKRLLLHVPGNCLSQTDVEKVLHSLKSAQVPNVLVLQGASSATQSCKHFVYA
IDLIKFIKRIYGNYFTIAVAAYPNCHPNSATEWDDLVHLKKKVDAGVDFVITQMVFNYEV
FNNFCRKSKQFLIDTPIIAGVFIISSYEGFMTMARLCKVEVSNEITSVLEANRNNEESVQ
NFGIFVCVSFIRQVLSHNNDQVLGVHFFSLNKLRLVRKVCKILGFLDVHIERPLSSAAST
VLRHK
>A0A7C1A213|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MNLREKLAANKFVVTVELDPPQTLNLDKILNEVNSNNFRKVVDAVNVTDCPLAKLRMSPI
ALSHIIQEKIGLETIFHITCRDRNLLGLQAELLGASVLGVRNILALTGDPPEMGDYVKAT
GVYDVDSVGLIKMVNSLNNGYKYLNGDLMDKTDFFVGAAVNPTALDPKKEIERFEEKVSA
GINFVQTQPIYDLGLLEKFLKITSRIKIPKIIGIMPLKSYKMVDYINKNLPGIFIPSGVK
ERMKGKDAKEGIKIAQEIIEEIRKIKEVAGIHIFPLRDMDLVCRLLNQSLVFG
>A0A7V9JQW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MASRFLERLQTGPAIVADGGMGSLISSAVPHLRCPEEANLRAPESVVSLHVSFIRAGADL
IETNTFGANRRKLATHFLEDEFERINSTAVRLAREARDVCGREVFIAGSIGPLGEFEEDR
ARRGDLFAEQAGLLEGRGADLFMIETFFDLDELETAIRAVRASSTLPIVALLTFDEDGET
LGGVGAREAAERLGGLELAAIGANHGAGPQAALAALSEMRSDGRVLAALPNVGLASMSGP
RIVYPHATPDYFSQFAAHARELGAGLIGGCCGTTPAQITAIRAAIEDGRAPRAPLVPHER
TIVAHEDEGAHETELARMLRTGEFVVSVQLDPPLGGSNRALLDVARRLKESGRTRLVDIN
DNARARARMNALMASIAVERVAGIETIPHVTSRDMTVMGLEAMLLGAHAEGIRNVLAITG
DPPDVGDYPGSSGVYEVDAVGLCQLVSRLNHGENFNGKAIDAPTSFYLGVAVNPSADDLE
HELERFRRKVEAGARFAMTQILFDLSYLDAFLERLGGSSPIPLLVGVWPLTSFQLAERLH
NEAPGIVVPEPVQERLRAAGPNAARVGLELARDLLAETREKAAGAYLVAPFRQPLGVLDL
LAD
>A0A538L1V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
RLPIVALMSFDAGGETIAGVSAHEAGERLCALGLAAFGANHGAGPAAALRALSDMSGEDR
VLAVLPNVGLASMSGKRIVFPHATPAYFGEFAAQARALGAGIIGGCCGTTPAQIAAIRAA
VPLELSERELVVALGEEQRETELARALREGEFVVSVQLDPPLGANPEALIDTARAVRDTN
KAQFVDVNDNPRARARMSGIMASVAIERFTGVETIPHLTPRDMTLTGLESILLGAHAEGV
RNILAVTGDPPEAGDYPGRGGVYEVDSIGLVELLTRLNRGEDHHGRAIDAPTSFFTGIAV
NPTADDLGLEAERFHHKVAGGARFAMTQILFDLEPLAAFRDRIGGWPIPILVGVWPVRTV
ETLVRVHNETPGIVVPEHVQARYRRAGANAREVGGELGHELIEDAREVAAGVYVMAPFRV
PMNVVDFLPELVHPDAQEPVETGVRRSESSTRRTTEAGTP
>A0A7V9RAS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSRVLERLEEGRVIVADGGTGALLSARVPRLRVPEEANIKAPESVIGVHHGFIRAGADLI
ETNTFGANRRKLSVLLLEDRLTEIVERGVKLAREAREIAGTDVLIAGSIGPLGDLEGTHG
GEDAFEVFLEQARLLEGRGVDLFMVETFFDLEELETAIAAVRDVSSLPVVAQLTFDEDAE
TLAGVGARDAFERLRSAGVAAVGANCGLGPQAALAALNEMNGAANGTPLTAQPNVGLPSR
SGGRIIYPNATPDYFAEFAAQARNLGARIIGGCCGTTPAQIAAIRAAVEEGREPRVRLLA
LERDIAPHVAQVSEQTVLQRMLEAKQWVVSVELDPPKGTNMEAMLDVATRLQASGVVHEV
DINDNPMARARLSALMAAIAIERTVGLETIPHVTPRDASIMGLQSQLLGAHAEGIRNILA
VTGDPPHVGDYPGSSGVYDIDAIGLTALLSHLNRGEDYSGKAIDAPTSFYVGVAVNPSAE
DLETELARFRQKLESGARFAMTQALFDIAYLDRFLDALGGESPIPMLVGIWPVRSFQLAY
RLHNEVPGITIPDPVLRRLEDAGPDAARVGLELGRELMEASRSRAAGIYVIPPFKEPAAA
LELLDV
>A0A7K0TTK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSILREKLENTSERVFTAEFPSIDGGGMDSVIKNAARLAPWFDAVNATDNPAAHAHTSNT
TTAIAMKMHDLEPIMQIVCRDKNRIAIQADMIGASLHGITNLSLLTGDDVTAGDEPEARR
VFDVDSAQAINMARIMATGTYLSGRKINPAPDFYIGAVENAAAPPFDYRIQRALKKHRAG
AQFLQLQICYHPDRLEAFCKGVAEVAPDLKLIPTIVLMKGAKGLAFMNDKVPGIDVPADV
LARASGASDPAQEVYNLTLELAQHALSLPGVRGLHVTDFRHDETLDLFMNDLGRTPKRQG
>A0A7K1IRD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSDASVGIVDQALSNGRASISFELFPPKTAQGEKNLWEALHELDALTPTFVSVTYGAGGT
TRDLTVRITERIASQTSLSPVGHLTCVGATRDQVQGVIEQYRAAGVRTVLALRGDPPGGL
GTPWVQHEGGFKHADELVAMLASYGDMSIGVGAFPDGHPESVSVQQDADVLAAKQAAGAH
FAITQFFFSADRYFESVELAKSAGCSMPIIPGIMPLTNFTQVQRFAELSGVQVPSELAKR
ARAVADDPEAVRELGIAEATRLCQQLLDGGAPGLHFYTLNRSSATREIYANLGLS
>A0A537TTY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSSEEEKRVSHRDRRMSRALERLERGPVIVADGGTGALIASMVSRLRCPEEANLKAPEAV
ISVHLGFIRAGAGLIETNTFGANRRKLSAQLLDDRLEEIVQGGVKLAREAREVSGADVLV
AGAIGPLGDFDGGAAADDAYEIFVEQAQLLEARGVDLFMVETFFELGELEQAIAAVRAVS
ALPVVAQLTFDEDAQTLAGVGAAEAIERLRGLEVAAVGANCGLGPQATLSALSEMAQHAD
GIALTAQPNVGLPSRSGGRLVYPNATPDYFAEFAAQARSLGARIIGGCCGTTPSQIAAIK
AAVDAEREPRLQLFVAERELGTRAVVAGETPGELARRLAEGEWVVSVELDPPKGSNTDAM
LRTAARLRDSGLVHATDLNDNPMARARLSALMAAVAIERIVGLETIPHVTPRDASVMGLQ
SQLLGAHSDGIRNVLAVTGDPPHVGDYPGSSGVYEVDSIGLVSILARLNEGEDFAGKAID
APTSFYIGVAVNPSADDLTVEIERFRRKVEAGARFAMTQALFDLGYLDRFLDELGGETPV
PLLVGIWPLRSFGLAFRIHNEVPGIVVPEEVQRRLADAGPEAAEVGAELARELVHEARSR
AAGVYIIPPFKEPEAALELLAGLD
>A0A7X7GBL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNGFKAACLSGRFVVTSEIGPPKGTDIESVVADIDLLKDRVNGLNVTDNQSAVMRMGPAA
IAHEIIARGGEAIYQLTCRDRNRLALQSDLLAAHALGVRNVLCLTGDHPCIGDHPQAKPV
FDFDSVHLIQCAGLLNDGVDWNGIELQGVTDFYIGAVVAPDVDPVKPQLFKLSKKVEAGA
GFFQTQAVYDMERFAEFMVTVRDITAGTQVKVLAGMLVLTGMGMARYMNASVPGISVPDP
LVQELADAPEGEAAMVGADICARHIRFLCDEGICDGVHVMALGRADLVPRILDQVGVL
>A0A7V4N0B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
DSVQLLRAIRELEAGRDLGGNALDGGVEFCAGAIVTPEADPLEPQLIKFEKKVDAGAEFF
QTQAIYDLDNFASFMEFARQYPVKILAGIVLLSSAKMAQYMNKNVPGIFVPQALIDELAA
AVAAPDAPKGAGLAKGIEIAGRMIREIRENRLCDGVHIMAIGKEEVVPDILAAAGMADWQ
PTGVIV
>A0A6I2ZDT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRSTFSFEFFPPKDAQGEARLWQAMEGLTSTAPDYISVTYGAGGSSRDRTIAITSEITSR
TKIPTVAHLTCVGSSKGEILDVLNRYRDAGIKSILALRGDPQGGPSAPWVSTPDGFTHAD
ELVSLAAEFGDFTIGVAAFPDGHPASGGNFDKDISTLLRKEDRGASFAITQFFFGVEKWS
SMVNRLAEAGSSLPIIPGILPITNFKQLVRMSDLNGTPIPAEILQIFAPLENDPDGVRKA
GIEIATKSCQELLAAGAPGLHFYTMNSSTATREIYTNLGITR
>A0A285ZB17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. LAIL14HWK12:I8|TrEMBL
MSLLKTALHEKTFVCVMEFVPKPSSERFAAMQAIMARGHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSSPVPALPHFSGKDRERHHLLAQLQRMDADGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEDEGGAQYFKAEKKLAAGADFLTLQLGF
DASKHQEAQAWMNRQPNPKPLLACLMSITHGRAAMLDHVAGVTVSPSMRDMLEAEAAVSK
AYAQARSVDRLALQVIGVKLMGYAGVHLSGIHELKQLLALEKRLEYWQAQLHSLEQWAPA
WAASWQVPGLPAVAFHPPAASWRQGESKVSASSTEKARYHLLHAFHALLFSRNNLLSKAF
GWAVRQPLWASASGARVLHGVERAVKRPLLGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTSLNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVQTRHRSSWPAWFAAQAP
QRLKACSKPRTQPES
>A0A6I3H434|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MQIGAMKSDGAPTFSFEFFPPKDSEGESRLWSAIDSLRSIAPDFISVTYGAGGSTRDRTI
KITSEITARTKVPTVAHLTCVGSTRTELLEILTKYREAGINSILALRGDPVGGPRAPWTK
TDGGLDHADELVMLAAEFGGFTIGVAAFPDGHPATDSATNQDIEVLLRKEQLGASFATTQ
FFFEVDKWAALVEKLAAQGSSLPIIPGILPVTNVKQLNRMAELSGTPIPASISQAFDAIG
ENPDDVRKLGVEIATELSQKLLDAGAPGLHFYTMNTSTATREIFENLKKR
>A0A7C1PRV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRSGSTLEKVLKAGAFAVTAELGPPKGADAQVIIDKANILKGHADAVNITDNQTAIARMC
SMAAARLVIDQGLEPIMQMTCRDRNRLAIQADILGAAALGVKNLLCLTGDHQSFGNHPQS
KGVFDLDSITLINMVKDMRDVPAFQCGEEITMAPELFIGAAANPYADPFPFRAIRLAKKV
DAGIDFVQTQIIYNVEKFEEFMAQCRELGVSERCHILAGVAPLKSAGMARYMKKRVAGMD
VPDQVVERLSSATDAQDEGIDVCVEVIERVREVEGVAGVHIMAVEWEESIPEIMKRAGLK
PGSASL
>A0A7C2I0L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTAPAPGGARATGRLARILADGAFAVTAEVVPPASADLGAVTDQARALVGYADAANVTDN
PRSSAHMSPLAGVAAVAAAGVEPIVQLTCRDRNRLALTADLLGAWALGARSVLCLTGDPA
STGDHPEALEVHDLAVTDLVRLAVRLRDEGRLLSGAPVDPAPRYLVGVADVPLARPYDPG
RLDRKLDAGADFVQTQIVFDVDGLGEWADGARARGVFERARVIVGIAPLRSARQARYLDE
QLPGVVVPPELVRALEEAGPEAAATGVRLAVGILERIRGVEGIAGVHVMGLGREDAVRRV
IEAAGLVPRPTLAGAQPRSSIGT
>A0A1V4TXA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccales archaeon PtaB.Bin215|TrEMBL
MSVSQLQGTLDSGKFAVTAEIGPPRSCEVEKLREMARMLKGSAHAFNLTDNQAANVRMSS
IASSVICLQEGLEPVMQMTCRDRNRIAMQSDVIGASAFGIRNVLCISGDHQTFGNHPQAK
NVYDLDSIQELMVLRQLREGKNWSGETLPEPPQLYLGAAANPFADPFEFRVTRLAKKVDA
GAQFVQTQCVLDVERFKRFMSLAVEKGLHEKVHIIAGVIPLRSHRAALFMKNKVAGMSVP
DELVDRLRRASDPKEEGIRMCVEMMQELSSVKGVHGVHITAIAWEDVIPRLVNEAGVRP
>A0A7Y4HXF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. 260|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNPEMETHLWETVEELKKWNPDFVSVTYGAGGSTKAPT
LDAV
>A0A1V4YCI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomethylovorans sp. PtaU1.Bin093|TrEMBL
MAVTFREKLRSDRFIITTEITPPKGVKTSSFLSDAEQLKQHVDAFNVTDNQRAVMRMSPL
AVGKLLKDAGHEIILQITCRDRNRLALQSDLLGAWALGIQNICVMTGDHTTKGDHPGAKP
VFDLDSVQLLEVVRKLKEGHDLSGNSLEQTPDFVVGAVSNTDPTQTMQHIKLRKKVSMGL
DFIQTQAVYDAEEFACFLEKISDIDVPIIAGVIPLRSAKMARFMNTSIPGIRIPDEIISR
MESAEEPVQEGMKIAVQLIRELKNMCRGIHLMPIGQHTDSKEILKMSGSTPGRQYNEQ
>A0A543A003|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia sp. HK171|TrEMBL
MSFPISFEFFPTKTPEGAAKHVQVRKNLYARKPQFCSVTYGAGGSTQAGTFNMVRDIQSE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPHSDLEAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A538EW39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAHGLPSVMPGGQPSIGALIRGTAPTFSFEFFPPRDADMDRQLWRAIRELESLRPSFVSI
TYGAGGSTRDNTVAVTERVATETTLLPMAHLTAVNHSVAELRNVIGRFAGAGIRNVLAIR
GDPPGNPQGEWIRHPSGVLYAEDLVRLIKDAGDFCVGVAAFPYKHPRSASVEADTEHFVR
KCRAGADFAITQMFFDAEDYLRLRDRVAAAGCDTPIVAGIMPVTSMRTIERSEQLSGAPF
PPALAAQFERIADDPAAVRRLGIEQAGALCERLLAEGAPGIHFITLNRSTATREVWQQLA
LGARA
>A0A538JB14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTRIADILAGGRTFSFEFFPPKNEAEQATLVRTLRDLEPLDPSFVSVTYRGGRESRRRTH
DLVVGMLRTTTLTPMAHLTCVVHSRLELAEILVDYRKAGIENVLALGGDPPVEASDGAGE
LAFALDLVELARAIGGFSVGVAAHPELHPRSPDRATDRDHLARKLEVADFAITQFFFRVE
NYLDLMDDLSARNLDKPVVPGIMPITNLKSVARMAELSGAAVPREVVERLTAAGDEPDDV
RRMGVEIATELCEKLLAEGAPGLHFYTLNRSTATREIYTNLALAAG
>A0A3S1I9J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M5C.F.Ca.IN.020.14.1.1|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFAEMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFD
GLQKDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A2E6VJE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGSNQKANNSRGGKSTQLRLIDGMTYELIPLKNVYEQAEFLPQASTISITCSPAKNIEAT
LELCENFLSKGHETIPHFAARMVESEEHVTRIVKRIEALGIKTVFIIGGDADQRGPFTDA
PGLLNSFLDKNPKIETVGIGSYPDGHPSIPEAALAESLIRKQEMIYESNLNGYMATQMCF
EAETISGWLENCRKSGVTLPCHLGLPGVVDMKKLINISLRLGVGVSTRYLKKNRKSVLKL
LSARGYNPNKLIVPISNHADELDIAGIHCFTFNAVESTTNWRTKAINRLI
>A0A3A4V6W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARFKSGSNLEKVFLSGTLAVTGELGPPKSADRKVIAEKADILKGYVDAVNITDCQTAIV
RTSSIASAAILMERGLEPIVQMTCRDRNRIAIQSDILGAAALGVKNLLCLTGDHQSFGNH
PEAKNVFDLDSVHLVSCLKNMRDKKIFINGEKMDVAPKMFIGAVENPFADPFEIRAPRVG
KKVAAGADFFQTQIIYNVPKFKKWMKQVRDLGLHKKAYIMAGVAPLKSAGMARYMKNFVP
GMDVPDEYIERMVEAKDPKDEGINVCVDIINQVKKIEGVAGVHIMAIEWEEAVPVITERA
KLLPRPTL
>A0A538AXJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTVRAESRLERLLHHGVFCVTAEVVPPRSASPEGVTAQARGLVGYADAVNLTDNPTASAH
MSVVAGAGLVAAAGLEPVAQVTCRDRNRLGLTSDLLGAWALGARNVLCLTGDPPIVGDHP
EAKGVYDLEVTELIGLVHSLRADGRLLSGAQIESPPRFFIGVADVPLAPDYRFDRLERKA
DAGADFVQTQIVFDVGAFEAWADAARARGILERMFVLAGVAVPRGPKSARYMRRHLPGVL
VPDRVVSLLEEAGADAEVEGVRLAVEVVAKLKTIPGIAGIHVMGLGQMGPVRRVIDAAGL
VPRPAVA
>A0A3P8UWB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cynoglossus semilaevis|TrEMBL
MVNQVQQGDGSWQLCKADPSGSSSSGASSRESSRCSTPVLDSDGSHRLRDKMRRRIESGD
HWFSLEFFPPRTASGAVNLISRFDRMGAGGPMFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQTKEKITGYLAKAKRLGLKNIMALRGDPVGSDWEEEEGGFNYAVD
LVKHIRSEFEEYFDICVAGYPTGHPEAESYQNDLQHLKEKVEAGADFVITQLFFRAESFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRNY
GIQQAVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWVEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELKNEKSVFEVFTNYITGQANPSGHKVMCLPWNDEPLAPETNLLQDELERVNKR
GVLTINSQPSINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVHGHNLTNAADMQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIEDMFETLDAPPEPTEE
>A0A524KW05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MNLREKLAANKFVVTVELDPPKTLNLDKILKEVDCDNFRKVVDAVNVTDCPLAKLRMSPI
ALSHIIQERIGLEAIFHITCRDRNLLGLQAELLGASALGVKNILALTGDPPEMGDYIMAT
GVYDVDSIGLVKMVNKLNNGYEYGEYELKDKTDFFIGIAVNPTAQDLTKEIKRFEEKVSA
GANFIQTQPIYDIGLLERFLKLTAHINIPKIIGIMPLKSYKMVEYLNNNLLGIFVPPGVK
ERMRGRDVEEGIKISREHISEIRKFKEVAGIHIFPLRDMNLVCRLLD
>A0A8B3L606|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1A.F.Ca.IN.020.04.1.1|TrEMBL
MEKAAIRPSSIGASIEMAPSQVIDSPDLPGLFPSGVRVYITDIGLADTPTLVKAARRVAD
LGYTAVPHMAARRLTTRQALETRVKALAEEAGVRDLLIIGGDVATPAGSFSSSFEVLETG
FVDKYGIAEVGVAGHPEGSRDFGDEAAIAALRMKSAWAERTGAKMRVVTQFGFDADKFIA
WADGLAVSGVDLPIHLGVAGTAKITTLLKYAALCGVGNSLNFLKKRSASLAALATSHSPE
SFVGPIEHHLRAKPESAIAQLHVFPFGGIKNTARWLYERGSWQDLEADDRSSIA
>A0A1D4L567|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus caeli|TrEMBL
MNQLLDKLQNNILVADGAIGTILYSEGLDTCPEAYNLTHPDKVERIHRTYIEAGSDVIQT
NTYGANFEKLKVFGLEHKVKDIHQAAVDIAKKAANDETFILGTVGGFRGIKQEDLELSSI
QYHTEIQVATLVEAGVDGILFETYYDLEELTNIIKATKRKYDIPVIAQLTALNTNYLRNG
TEINDALQQVAESGADIVGLNCHHGPHHMQQSFSHIELPNHAFLSCYPNASLLDIENSKF
KYSDNAAYFGKVAEQLINEGVRLIGGCCGTTPEHIQYIKSSISGLKPVSEKNVVPITKYI
NQKEQSSKKQNLTSKVKSRPTIIVELDTPKHLDTDLFFRNIKKLDDADIDAVTLADNSLA
TVRISNVAAASIIKQRFDIEPLVHITCRDRNLIGLQSHLLGLSLLNINEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNRGINTDGDALKTKTNFNIAGAFDPNVRKLDGAVRR
LEKKLESGTHYFITQPVYSKEKIKEVYEATKHIDAPLFIGVMPVTSYNNALFLHNEVPGI
KLSEDILAQFEAVKDDKVKTKELSIKLSKELIDTVHEYFNGLYLITPFQKVDYTLELANY
SKSITSTTQEAIL
>A0A833FVF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiaceae bacterium|TrEMBL
MAQTSPPNRLPVSIEVAPRALIAAGDISGLIPKGTAVYIVDMESTIHTNAEIAAAASTIR
KAGAVPVPHIAARRLLGLATLEERLKRLSSEAGVTDVLVIGGGAREPQGPFASSMDVLSS
GLLDRYGVKRIGIAGHPEGSPDITPEQIETALAQKIEFGKRTNAEMRIVTQFGFDTDRLF
KWAAGLQAAGVSLPIHAGIAGPASIASLLKFAVLCGVKASTEFLSRKGSAIATLLTGYDP
EHMAAEIEARAGLPGDAIAALHIFPFGGIKKASEWLRRRGSWTAPSLPTHARETP
>A0A839N9G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flexivirga oryzae|TrEMBL
MTTRPIPELLAEEGPSFSFEFMPPRSERAEAVLWNSVRRLEQLHPTFVSVTYGAGGSTRD
RTVRITGRIEQETTLRTMAHLTCVGSSVSELRRVVGEYAAVGIRNVLALRGDPPGGPSSV
WEAHPEGLDHADQLVALVRSLGDFTVGVAAFPDKHPESTSLEQDADSLVRKAEAGAAFAI
TQMITDVDAYLRLRDLLDRRGCTMPVIPGLLPVTAPGQLQRLTELNGQPLAQDVVRRIAD
AGDDPVAVRREGIAICTEHSQRLLREGAPGLHFMTMNKSTATLEVFANLRQVSLV
>A0A6G9VU80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurospirillum sp. ACSTCE|TrEMBL
MIDSFIEKLKYDTFLTLETTPMHEPTFEPIIEKIAQFGLDKKVDGFSTTDNPLARLKFNA
FFGALKLQTRFTKPVITTMSMRDRNKVALQSDLLGANAYDLRTILCLTGDPASASDQPAV
KGVFEGNSTLLLEIIQCFNAGIDYSGKPFKTQPKPIYPFAVCNAHANTPKNLMKKMATKI
EHGAVGIITQPVYSVENATMLLELLKDAKSAANKEQSHTQLILGFFPIVKLRTAQFLAAH
VPGIYVPPLWMEKLAKAKKISEEEEKKVGFELSRNAFLALKKVHPKIHMMSANNFELVAD
LLQS
>A0A7K4LJC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crypturellus undulatus|TrEMBL
MVNENQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDK
WFSLEFFPPRTASGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPAGEEWQEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAENYEADLRHLKEKVLAGADFIITQLFFRSETFLK
FLKDCQAIGITCPIVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWTEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYISGELNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYETRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A837XYV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus atrophaeus|TrEMBL
MGLLEDLKHQVLIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHEAYVQAGAHIIQTN
TYGANYIKLSRHGLEDETKKINKEAVKIARASSGGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAQEVLKIARKETDLPIVLNVSMHEQGVLQDGTP
LSEALRSLVGLGADVTGINCRLGPYHMIEALTEVPIFDDAFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSAIEFRKQGARIIGGCCGTTPSHIRAMADAVGGLEPITEKDVKIRAQETIS
IQHERTEPGLDEIASQKRSIIVELDPPKKLNFEKFLSAASELKDAGIEALTLADNSLATP
RISNVACGALLKQQLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLNDILAVTGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGRKTNFSVAGAFNPNVRHLDKAVKRLE
KKIDCGADYFISQPVYSEQQLVDIHNETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIREKMALAGEDKQKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
KKDEKRENVFLH
>A0A8B4MZX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKHHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KKAKSFLIKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
SGKEFSPEITHFSCQPTSKQLIKYRQLHVMHEALFGSKIAKGVGSFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILREKLIPTVPLETRGTSSWKNWYLATEA
>A0A6H3T5W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHKELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPIAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREYSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A1H8PTP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. CF517|TrEMBL
MTSHNFSIEFFPPKTAEGAEKLRATRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILA
AGEDAAPHLSCVGGTRESIRAILAEFKSHNIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGEWFHIEVAAYPEVHPQAKSPRDDLLAFERKVKAGANAAITQYFYNADAYFQFVD
QTRKLGIDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASYGDDTASIKAFGLDV
VAQLGERLLAGGAPGLHFYSMNQAAATTALWQRLV
>A0A1N6U8G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter tolerans|TrEMBL
MASVPLSFEFYPPKTDDQAAQLDRTLGKLKAYSPEFVSCTFGAGGSTLSNTSETVRRMRT
EHKLEGTPHITCVGGSREEIRALLKLYRALGCRRIVALRGDMPSGMIGQGEFRYANELVE
FIRSEHGDHYHIEIGAYPETHPQARDAQSDLINFKRKVDAGANSAITQYFYNADAYFRFV
DDVRRLGIDIPVVPGIMPISNFTQLRRFSEACGAEIPRWAEQRMRGFGDDVNAVREFATD
MVAAMCERLIDGGAPSLHFYTLNMAKPTLNVLARIR
>A0A2W5X786|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eremiobacteraeota bacterium|TrEMBL
MRISEGLRARRPFFSFEFFPPQDDAGVAQLLETIETLRSLRPAYVSITYGAGGSARARTV
ELSKRIQNEIGLTVMSHVTCVGSSKRDLRNLFYELRDSGIENIMALRGDPPRGQSAFVPD
PNGFAYASELIAMLRREFDFCIGGAAYPEKHPDAVSFEDDLGHLVEKVNAGAEFLVTQLF
FDNEAYFRFVERVRAAGIRVPILPGIWPITNYKQIARITAMCGSILPPKLRSELEARAEE
PEAVKELGVSYATLQCTDLLRRGAPGIHFYTLNRSPATRAVVSALHAATAWQTYAELLAG
SQPPPIGKLA
>A0A1C6VYI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora chersina|TrEMBL
MALGLPSVLPNPQPAIGELIRGGRPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRHVIGRLASVGVRNVLAVR
GDPPGNPGGEWIEHPEGVRYAEELVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQLATIERSVQLSGAPF
PPALAERFAQVADDPEAVRRLGIEQAGEMCAKLLDEGVPGIHFITLNRSTATREVWQRLR
ADARV
>A0A1I4REL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanolobus profundi|TrEMBL
MSGTFKDKLLSDNFLITAEISPPKGTDLSEAISDAEVTRGWVDALNVTDNQKAVMRMSPL
AVSRALLDAGHEVIMQLTCRDRNRLALQSDLLGAYAMGVRNICIMTGDHTTKGDHPKTKP
VYDLDSVQLLTIIKKMKEGYDLAGNKIDEPPEFVVGAVTNTDPSKAAQMMKLRKKAKTGI
DFIQTQAVYDISKFEAFMEANGDIDIPIIAGVIPLKSAKMARYMNKNIPGINVPDDIIDT
MERSDDPIEQGMSICSEAISELKKLCRGIHFMPIGKHDNTPIILEMAGIRKNDQ
>A0A5N6ZQQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus caelatus|TrEMBL
MHIKEKLAQNEAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAADGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGATF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYSAFIRRANWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDQLKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIRDLSHLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLVE
LNNRGILTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIESNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDNWYLVNIVNNDFHNTYDLFDLFKDLNVRDFDVEVTADNADSK
SQENEAAGATAN
>B0K6M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter sp. (strain X514)|TrEMBL
MLKNENLCTKLKKRKFVVTAEISTPKGVDITKTIEEARKLKGIVDALNITDCPMANMRMS
PIAVAHLLQDHLNIEAIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDDPSRGDTPQ
AKGVYDVDSIGLLKIISAFNRGYDYNGNKLDSPTEFCAGTTANPNDLRDEALEKLKVKIE
AGAEFIQTQPVYDEEILFKFIEKIKNFNVPLLIGILPLKSYKMAVNLNEKVPGIDIPEKV
LERLKDGGREEGINIAVEFIKRIRSEVAGIHIMPLGSTNVVLEIISRVDDLVCDFAENNV
QMN
>A0A502GVG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter nivis|TrEMBL
MKVTEHLAQAKGKTLFSFEVLPPKKGENIHTLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFTKEETENALIDLHFLGIDT
VLALRGDPIKSEGVFKPEPDGHAYACDLIGQVADLNKGEYLDQEQDDAWATSFCIGTAGY
PEKHFEAPNYGADIRYLKHKVDRGADYIVTQMFFDNEQFFDFERRCRAAGIMVPIIPGLK
PLTTKAQLSALPRNFFLNFPEPLVEAISQCRDNEAARIIGTEWCLNQSRELMAHGVPSLH
YYSMGKSENIRKVAKELF
>A0A3N7J735|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Albitalea terrae|TrEMBL
MSNTKQVPISFEFFPPNTPVGDEKLRTVVQELGAMKPEFFSVTYGAGGSTREKTLNTVMA
IAKAGFEAAPHLSCVGSTRGGLKEILDTYRAQDIHRIVALRGDMPSGTAMAGEFRYAAEL
VRFIRETQGKDWHIEVAAYPEYHPEQRYARRDLQHYVDKVRAGASSSITQFFFNPDCYFH
FVEETKKMGADAPVVPGIMPFHNYAKIAQFAQRDGIEIPRWVALKMEGFMDDSASIRAFG
LDVVAELCERLIAGGAPGIHFYTMNQSALTIELCKRLNLG
>R5MF08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:149|TrEMBL
MKIRDILAQGKPTLSFEVFPPKAEDKYDSVEEAAIRIARLKPAFMSVTYGAGGGTSKYTV
DIASSIKNQGVNALAHLTCVSSTKEEVRRVLGELKTRGIENVLALRGDIPEGGPLAHDYR
YASELIREIRSFDGDFCIGAACYPEGHVESANKTEDIEHLREKVEAGCDFVTTQMFFDNN
ILYNYLYRIRERGITVPVVAGIMPVTNARQIDRICRMSGTYLPARFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAEQIKNSLSEIL
>A0A2H0XJK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium (Candidatus Stahlbacteria) CG08_land_8_20_14_0_20_40_26|TrEMBL
MLDFRERIKKGVIIADGAMGTMLYSLGVPKGHCYDELNLSNPDIVKTVHRSYVAAGAELV
ETNTFGANRFILERYYNLGKKVRDINYRGAKIAREVAGDGIIIGGSVGPITRPYESAIKL
SKEERRDIFREQITPLLDGGVDIIIFETMAGVEEIKDAIFALQKLYGDFPFIAQFSFMDD
GKTLLGVDGVNAARELKGVEIMGANCGSGPKGIYSALKRMGCVTDAVLSAQPNAGYPGFV
YGRFLYPATPSYFAEYARRFVDIGVTIIGGCCGTTPEHIRAIKESVSEMKPKPRKIATIR
APVEKVSEEVEVVTQLKKKLQKGFVYTMEIDPPRGGIVERELAGARLFKKVGGDAINIAD
NPMAKLRMSALPLAYLIKRETGLECILHFTCRDRNILALQSELLGAAALGINNILALTGD
PPSVGDYPFAVAVFEITAKELVETIGSINHGYDRLGNPLAGRTNLFVGIASPIRNVDPDR
IWEKINLGAGFIQTQPVFDIELLRKFISFNFGIPVIAGLLPLHSIRQAEYFANEVPGMYI
PEEIIERMKNGESGICIAKELLKEIRKTYQGVCIMPQGRYEIVKELMGEEVSI
>A0A3P7F9K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Toxocara canis|TrEMBL
MSHFFNLRSYRGGSAISGYPTCHPEAPSYAADLRYLKSKVDAGAQLIITQLFFDADVFEK
FVHDCREIGITVPIIPGIMPIQSYESIRRIAAVSQLTIPESILNTLEPIKHDDDAVRSFG
IRHAVEMCRHILSSGSALSVHLYTMNRESSCREILQELGLWTRTPMRSMPWKSFDGNHPL
RAKEDVRPIFWSTRPKAYVFRTRDWDEFPNGRWGNSSSPAFNDLADYYLFYLKGQPTKDE
QLRMYGQELESVEAVKKVFVGFITQQPNEQGVKVTRLPWNEQDLDAETNIIRDQLLWCNE
NGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQK
>A0A6N7C0F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter nivimaris|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALST
RGTTEIAPHMSCIGDDKSEIAELLEYYKTLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
YIREHSGDHFHIEVASYPEMHPQARSFEFDIDNLVNKYQAGANASITQFFYNADSYLYLR
DKLEKRGIDTVAQPLVAGIMPITNSSNLLRFADSCGADIPRYVRKQLTDFGDDSKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLTA
>A0A7L7VR66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. BIM B-2242|TrEMBL
MSPPSLIETHPNLTETAPVALSYELFPPRSPAAAESLWTTIRELEATEPDYVAVTYGASG
SNRDTAVELIHRLVLETTLRPLAHLTCVGNTPDELAEIIGDLLDTGVRGILALRGDRPQD
GEPPVAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVYFDTAQYADLITRARRAGVTIPIIPGVMPLTSLRRVTRLGELAGVQ
PAPELLARLAGADTEAERLRIGVRATVDLANAALDSGAPGIHLYTFNEHVSALEVLDKLA
LPRHVRSVGRRSAAVRSNATRHARLAS
>A0A496BT11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. AF27-14|TrEMBL
MKVIDLIRHSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A3N2MSF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Isolate-102|TrEMBL
MKVTELIASHGKTGFSFEVLPPLKGKGIAQLFRNIDILKEFNPLFINITTHRSEMVYKNT
PDGLYQKVSERSRPGTVAVAAAIQQKYNIPAVPHIICSGFSKIETEYALIDLNFLGITNI
LILRGDKAKHESRFIPNENGYSHASELQLQINEFNRGYFIDGTKMDIITGETFSYGVAGY
PEKHDESPNLDMDIAYLKQKIDNGAEYVVTQMFFDNSKYYDFVDRCRKAGINVPIIPGLR
PITTIGQLNILPKIFHVDMPMQLVSELMKCKDDNDAKEVGVEWCKAQCLDLMAHGVQSIH
FYSLNSTRSVERVAASIY
>A0A0C2IMC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporothrix brasiliensis 5110|TrEMBL
MHIRDMIVEAEKDGLPSFSFEYFPPKTAQGVQNLYERMERMHLFGPKFIDITWGAGGHVA
ELTAEMVTQAQTYFGLETCMHLTCTDMGEAAVNDALRRAYRAGCTNILALRGDPPRDKET
WEATDGNFCYARDLVRHICKTYGNHFDIGVAGYPEGTDDNKDEDMLLDHLKEKVDAGASF
IVTQMFYDVENFLRWLARVRERGITVPVLPGIMPIATYASFMRRVNHMGCKVPARWVEKL
EPVKNNDDAVREIGKSLVAQLCRDILAGGDVKHLHFYTMNLAQATRMVLDELDWLPSADR
PRPPPALPWKQSLGLGRREEAVRPIFWRNRGKSYVSRTADWDEFPNGRWGDSRSPAFGDL
GNAYGVGLPGTNARNRAKWGEPRSIADVASIFVRYLKGELQSLPWSESPLTGEADKIRQD
LIDLNKHGLLTINSQPAVDSAPSSDPVHGWGPPNGYVYQKAYLELLVPPALYAEVIQRVQ
AHPHLTYHAVTWKGKLETNAPGDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLG
ADWSRCFEAGSPSRTLIRGMMDEWHIVTIVNNDFHQPRTIFEVLAGLQLSDMDKEVEAEP
VEAPEATEATPVKPVKDAVDAQAAPVAA
>A0A087CS88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pullorum subsp. saeculare DSM 6531 = LMG 14934|TrEMBL
MSKPLFSLEVFPPKRTAPIGTIYDTLDGLHGVDPAFISVTYGTGKQSDRTITARITNTIR
TEYGIPAVAHLTAQYLDRDQTDEALDMFAQAKVAAVLALRGDRNPEREPAGVFMHASDLT
RYIRQTHPEMTVYGACYPECHPQSRDLDEDISWLKVKVDAGASHLISQLFYDNADYLRFL
DKARAAGIDVPIEAGIMPVTNAASVRRMTGMCSSKVPERLATILDRWGDDPNTLKEAGII
YASEQIADLVARGVDGIHLYTMNHPGVTRRIWQNVQGLF
>M4CTF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica rapa subsp. pekinensis|TrEMBL
MKVVDKIKSATEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPSFCDITWGAGGSTA
DLTLEIASRMQNVICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGEDK
FVQVEGGFACALDLVNHVRSKYGDYFGITVAGYPEAHPDVIEADGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRKIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAFGIHFATEMCKKILAHGITTLHLYTLNMDKSAIGILMNL
GLIDESKITRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYGTLSDYQFMRPRARDKKLQQEWVVPLKSIEDVQEKFKELCLGSLKSSPWSELDGLQPE
TKIINEKLGKINSNGFLTIHSQPSVNAAKSDSRAIGWGGPGGYVYQKAYLEFFCSRDKLD
TIVEKSKAFPSITYMAVNKAGNWVSNVGEADVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYFLVSLVDNDYINGDIFSVFA
>A0A1X2HD73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syncephalastrum racemosum|TrEMBL
MKVIDKIRKAEEEGRFFYSFEYFPPKTPQGVQNLYDRMERMQRFGPEFIDVTWGAGGTSA
DLTTELVATAQSVYGLETMMHLTCTNMPVEKIDNALKAAKECGCQNILALRGDPPKGQLN
WESCENGFSHASDLVRYIREKYGDYFSIAVAGYPEGHIDSPDQESDMKYLKDKVDAGADL
IVTQLFFDADVFIDFVKRCRDIGIKCPILPGVFPIQNYNGLKRVISFSNNHVPQRVWDEL
EPIKDDDAAVKEYGINLTVEFIRKFREAGINGFHIYTFNLERSSRLILERLQLVPDTESI
KPLPWNPSLTAKRAKENVRPIFWKNRAKSYIQRTESWDEFPNGRWGDSRSPAFGELDGYG
VSLKYPQQECLEMWGHPKSADDIAAIFAKYCKGTIAGIPWSAQQLDPETEVIRQRLAAIN
LLGYLTINSQPAVNGAKSSHEVYGWGPKNGYVYQKAYIEFFVSPQKLDELIAKISKNPQV
TFHAVNRQGDLKTNTQSDQPTAVTWGVFPGKEIVQPTIVESTAFMAWKDEAFELWNEWAQ
IYDRESETAKVILDVMNSYYLINIVMNDYVDENGIWKLFNLEIDGDLSAKLMGSQ
>A0A832J2Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
EPVKGGFTSSIELVETLAETGKFNIRVGAYPEPHPESPDTTADVEWLKRKIDAGASSAIT
QFFFEAETFFRFRDACEKAGIDAPIIPGIMPITSWTGIKKFAAGCGASIPAWLNDAFEKA
TRDNRTDLLSTAVCTELCSDLIDGGVEDLHFYTLNRPALTRDVCHALGVTPAVSLENVA
>A0A545B3Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MGTPKISFEFFPPQTLEASFRLWDTVRVLSPMQPEFVSVTYGAGGTTRKLTHEAVTTIGR
NYGLDVAAHLTCVNATRAQTMEIVENYAQAGVTELVALRGDAPKGAERFTAHPEGFASSV
DLIEALARDGRFKIRCGAYPEPHPDSADTLADVRWLKRKCDAGATSSITQFFFEAETFFR
FRDLCEKEGVRAKIIPGILPIQGWKGAKRFAQSCGTSIPTWVEEAFASEAAQQNEAPLAH
DLCTKLCADLLDGGVEDLHFYTLNRPTLTGKVCQSLGIAPDLGLDKVA
>K0MAH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella parapertussis (strain Bpp5)|TrEMBL
MTESTAPAFSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRT
LRNLGCDAAPHLSCIGATRDQLRDILAAYREQGVRRLVALRGDLPSGMGGDAGELRYASD
LVAFIRQETGDWFHIEVAAYPEMHPQAESPSADLAHFVNKVQAGADAAITQYFFNPDAYF
DFVERAQAKGVAIPIVPGIMPITNHTQLVRFSEMCGAEIPRWIRLRLAEYGDDKASIRAF
GLDVVSELCQTLLENGAPGVHFYTLNHAEATLGIWKALNA
>A0A7J9VHR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola sp|TrEMBL
MPNQPKDPFSSAGDVATLSDVVRSLTTGFSVEMTPRDVRKHPGLCRESLAAGTRVYLTFL
PRSPFGDTVKAAISLIEQGMRPVPHIAARGVADAAELDGMVGQLADVGVRELLVVAGSIR
TPKGTFTDTMQVLRSGVLARHGITRVGVAGHPEGSPDIDTDALATALREKNAFATEAGCE
MYLLTQFCFDARPIVAWERRIRAAGNWLPIHIGLPGLTSPKRLLKFGLACGIGPSLKVLR
KQTGGVLSLATTSAYYPDQTLFGLASAVRNHQDSLISGVHFFPFGATALTADWAKQIADG
QFQIDDRQGRLAVTA
>A0A1Q6DLE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium DB1|TrEMBL
MKSGSRLEKILTSGTFAVTGELGPPKNSDPEVVRKKARILKGHVDAVNITDCQTAIVRMS
SIAAGLITLQEGVEPVIQMTCRDRNRIGMQSDILGAAALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMVRAMRDEKKFQCGEEMKSAEPRLFLGCAANPFANPFEFRAPRLGKK
VANGADFVQTQIIYNVEKFTRFMEMVCDLGIHEKAYILAGVTPPKSLGMARYMKNFVPGM
DVPDDIISRMKDAKDKQEEGINICVDIINRVKEIKGVAGVHIMAIEWEEAVPEIVKRAKL
ATRPAFEEDAAVTQKPVEAPIEITTAPAEAVTSVDHEKLLAEARSEAEKIIAQARQEVEK
MRAAAAVSVPGGVATEYEDAGEHEMNERERQMALQSVQMGLNALRKAFNLTDDQFEALSS
FASAEAVLKRQPQEGGAAPAPAAAPEVKKATEPKVDAAAEKAAAEAKAAEEARKAAEAKA
AEEARKAAEVKAAEEARKAAEAKAAEEARKAAEAKAAEEAKKAAPAKPAPTAVAASAELA
VAELAVEKTSLAERSAKVPAASYKINYTGTIKETVLGSGDKALKVGGEASLPFYLFEGGM
PNKPVIAMDVLDVKPDEWPDSLARHYQGVLGNPLDWARKCINEYHAEAICLSLVSTDPNG
MNRSAAEAAKAASEVINNIDVPVIVWGCGNADKDTETLREITSLTGDKKVCLAPLSDANY
RSLGATAMAFQNPLVAASPIDVNLAKQLNILLQNLGVPLSSVMMDPSVGALGYGIEYTYS
VMERIRLAALTQQDEKLQVPIICNLGREVWKAKECRLPSDDMIGDMERRGIMMEAITATC
MLLSGGEVLIMRHPKAVNLTKSLINSLTSGK
>A0A497VH98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium lindanitolerans|TrEMBL
MKVTEHIEKANGKSLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEYKE
LPSGLLEKKIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VVALRGDAVKNETYFKPEKEGNHYASELVTQIANLNNGIYLDDELQNSSATNFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGASYIITQMFFDNKKFFDFVAKCRKEGITVPIIPGLK
PISTKKQLNLVPHRFKVDIPDELIMSIVRAKDADAVKQIGIEWCINQSKELIKEGIPVLH
YYSMGKSENIKAIAREVF
>A0A2D5IXC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTVPEISFEFFPPRDLEASFRLWDTVQVLAPLGPRFVSVTYGAGGTTRDLTRDAVATLHK
HSGLKVAAHLTCVDATREETLAIAQDFADAGVRDIVALRGDPPKGADRFVAHPDGFADSC
ELISALAAAGPFNIRVGAYPEAHPEAASAQADIDWLKRKIDAGASEALTQFFFEAETFFR
FRDACVKAGIDAPIVPGILPIENWKGASRFAKRCGTAVPQWLDDAFATAERDGRQDLLAT
TVCTELCTDLIEGGVDKLHFYTLNRPELTRDVCHALGVTPKAHLENVA
>A0A252C820|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter orientalis|TrEMBL
MSLSRLSVELIPRSADALRDDIAAVKQLLPAADTLNIPDLMRFPLRSWDAAAQMQPLFPR
IVPHVRAIDIAPDAPLPGANQPGLEEVLVVHGDPPADLAHRTYRNSTESIIRRYKKEAPH
LRIYAAFDPYRRAPWHELEEIARKKEAGAEGFFTQPVFDLKLFDLCREWLSGETVFWGLS
PVIGPRSRSYWETTNRVVFPKDFVPTLEANITFAQTVLKSLATDKGHVYLMPLRVKLEQY
LPALQAVLS
>A0A0D6NKV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter orientalis|TrEMBL
MTDMTGILSNWLSEMHIDGLLSRNSEAPILSFEFVPPRTDAMEQRLWHCIRHLAPLAPRF
VSVTYGAGGTTQTGTLSTVLRLKRETDLIPAAHLTCVGATREEVDGLARCYRDAGVNHIV
ALRGDPCAGYSPRPGGYAYASDLVAGLRRIADFDISVVAYPETHPTASSPDADLDNLKRK
LDVGATRAITQYFFDSEIYLRFLDRCLAAGITAPIIPGIMPVSNYEQIVRFSAVCGVTVP
AWLRHLFDGTAKNPELRRIIACMVAVEQIRTLQTYGLNEFHVSTLNRSDLTYAIAHVLGV
RPTETNASHNLTGLLETTEIPHDRETPADFDPTEGTQEGAPPFMLRTLFG
>A0A1E4YB19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. YK2|TrEMBL
MSSSSESHNAGIRISFEFFPPKSEEAEQQLWNTVEELSDWDVEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLATGVRRFVALRGDPPGGVGAAYQP
HPGGYANAAELVQALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRAAGIKIPVVPGIMPIQNLTQLKRFAGACGTNIPTWLDERFDGLDE
DVEERAKVAADVAAEQIQDLVRRGIHEFHLYTMNRSALVSAVLERLGLERKMDARAGAAA
>A0A642UJK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diutina rugosa|TrEMBL
MAKLTEKIAQLRPDQRFVSFEFFPPKTDGGFRNLIARLTRMSALNPLFVTVTWGAGGSTS
EKSLDLAATCQRELGLTTVLHLTCTNTNRQIIDTALARAKEAGIRNVLALRGDPPRAEEY
WTPDCDFHNAVDLVRYIKANYGDYFCVGVAGYPEGHVDGSDNAGQDPRKDMPYLVEKVKA
GADFIITQLFYDVDKFLAYEQLLQSYPELKDVVLIPGLMPVTTYKVFQRAAKLSHAKIPA
AIEQRVSAHQSNDDTVKQIGVDVITDIIAAIDAKTNGRIRGYHFYCLNLEKATASIIANS
QVLSSVIDEPTHINHDEAIASDDSDVEAPPKGANGARRRSSLVNANELAKDDAQRALVNK
ALLKDKRVLREISAGKGALGKDAIWDDFPNGRFGDSNSPAYGEIDGYGPSLKISTPNEAT
VLWGTPESTLDITRVFTAYLSGSIPLLPWADQALSPETALIQEELLELNCKGWFSLASQP
AVNACRSNDKILGWGPPGGVLYQKAFVELFVPKKDWREVILPRITEDVDAQTITYYLGDS
SGKIESNLPRQAESKTAITWGVFPSREVVQPTMVDYESFKAWNEEAFHLWVEWARCYKVN
SKSYQLLNSIHRDYYLVSLVHHDYPEEHALWDTLLQE
>A0A0P7YTF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium HLUCCA08|TrEMBL
MTRPAISFEFFPPKTLQGSFRLWRCVETLAPLAPDFVSVTYGAGGTTRQLTREAVDAIHT
EARLPVAAHLTCVDATRAETLDIALGYAEAGVSRIVALRGDPPKGSGGYRAHPDGFESSV
DLVAALAETGRFDIAVGAYPEKHPEAADQAADIAHLKRKVDAGATSAITQFFFEPDTFFR
FRDACVAAGIDVPIIPGILPIENWAGARKFAESCGTAIPQIVSDAFENATRDGNTDLLAT
ALATELCDALLQGGVAHLHFYTLNKPELTRDVCHALGITPELRLQNVA
>A0A1Y5G6S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|'Osedax' symbiont bacterium Rs2_46_30_T18|TrEMBL
MHANLATRLADPSRGVYFVGTTPPRAEVAEMDMQVIADKLLERLIAIDYDGLVVYDIQDE
SSRTDTPRPFPFKATYDSLAYSKVLSDKSGLPTITYKSVSARSKPEFSQWLEQAWVEYGI
QNIVLVGSPSSSGKINLPLKEAYKTLSDHQRSFNLGGVTIAERHHKKGDEHIRLKQKSVD
GCNFFISQAVYNADATIDLLQQYSALCKENAEKPKRIILTFTPCGSEKTLDFMHWLGIST
PSAVKTRILNADDSLAESITVCEENLQQILNYCMDLDIPLGLNIESLTNRKEEIDASIKL
FKLLKATLDLNLAKKSLSQ
>A0A851QPF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tychaedon coryphoeus|TrEMBL
MVNETQHACSASSSSRSDGGSSSGSESSKDNSRCSTPVLDSDRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWREDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDELERVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6M1TJ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter sp. HX-7-19|TrEMBL
MSTPRISFEFFPPQTLDASFRLWETVQMLAPLKPSFVSVTYGAGGTTRKLTHEAVGAIGR
NYGLNVAAHLTCVDATKAETLEIAEAYAAAGVTEIVALRGDAPKGAERFTAHQEGFASSV
ELVEALARTGKFKIRVGAYPEPHPDAGFAGADVEHLKRKVDAGATSAITQFFFNADTYFR
FRDACVKAGINVPIIPGILPIISWEGAKKFAARCGAQVPAALDEGFRVAARDGREELLAL
TQCTTLCARLIEGGVEDLHFYTLNRPHLTQAVVRALGITPEVALEKVA
>A0A840V145|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoprunum benzoelyticum|TrEMBL
MSFQKRLQAHEFVVLAEMHTPKGVNISRLMTDARRIKGRIDAVVIPDMDNGIMRMSAIAG
GVLMQQQGVEAIIHTYCRDRNRMALQGDILAAHVLGIQNLIVAHSEEMSQGDHSDAKTVA
DLDEIGLLGAIRQLQAGRDLAGFDLDGIPSFTVGCTIAPCADAAELEAELAVAARKIEAG
AMFVITPPVFDLSHFATQLPQFKKLGVPVIPTVFLLKSLAIAQYIANSEPGAHISDELTR
RIRKSSDREQEGIQIAGETVAALKTMTEGVMIQTLGWEHKLPAILDIAGI
>W0Z861|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. C448|TrEMBL
MSRSTQPVNKAAALELVSNYSLEMTGKDVPGLIEAKDSIPAGTKINVTFLGNEDLEMRVT
ASKAVRDMGFIPVPHISARRLSSQDQLEEFLGRLQEVGATDSVFAVGGDPAEPEGPYPDS
LSVIQTGLLQKYGVKEVSIAGYPEGHPDIATDVLWRHLEDKSAALKEQGLDATILTQFAF
DTDPVIDWVQGVRGRGIESTIRIGTPGPAGIKRLINFARRFGVGANAMIVKKYGFSLTNL
MGTAGPDKFVTDLSALLAADPASGEVKLHFYTFGGLKATADWAHQYVDGMS
>N9T6J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 102143|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLHIVHQELQRLNPEFFSITYGAGGSTRERTLATIHDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGNHFHIEVAAYPEMHPQADSFDADIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERLEKEGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1G0YNF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_57_35|TrEMBL
MDALCIKDLLDRRKSPLLSFEFFPPKDGLGMASLETAAAQLLSAKPDFATVTYGAGGSTR
ERTLQVCDLLRQMGYGPIMPHLTCVGSTRDELLALADRLHGLGYRNIMTLRGDPPQGETV
FQAVTDGLAHASDLVALLKTAHTDFCCGVAGYPERHPEAPSAREDIVHLKQKTDAGADFI
TTQLFFDNRCYFDFVEACRTAGIRQPILPGLLPAISLKQAQRMTARCKTRLPEELIRQME
EAGSEGDAAEEVGIQWAQKQIEELLGRGAPGIHLYVMNRSKAALTPAIADCFRRFRG
>A0A4V6JMM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leclercia adecarboxylata|TrEMBL
MTNVRIPHWMAKMYEGLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYA
ICHTLGVRPGL
>E4LA20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dialister microaerophilus UPII 345-E|TrEMBL
MSLREIFNRKQVFSYEVFPPRKNAGIDSVCETIKELKKLNPDFISVTYGAIGARNNTDTF
KIASLIKSYGIESITHLPCLELKKEEVLLKLEELRKLGINNILALRGDKPEDGYRKGDFK
YASDLITFIKEHGDFNIIAACYPEKHSDSKNIVEDVKNLKIKVDAGANQLITQLFLDNDY
FYAFKERCELADINVPIEAGIMPVINKRQIEKMTSFCKVETPKKFLKMMNRYEHNKIAMR
DAGIAYAIDQIADLITQGVDGIHLYTMNNPYVAKRIHEAINNLLLDKTEFLKEA
>B0BPD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus pleuropneumoniae serotype 3 (strain JL03)|TrEMBL
MSYAKEIDHLNHTLADLNGNINASFEFFPAKNEKMEMLLWDSIHRLAPLKPKFVSVTYGA
NSGERKRTHSIVKRIQQDTGLAAAPHLTGIDANPEQLRIIAQDYWENGIRHIVALRGDEP
AGYAKKSFFAKDLVKLLKEVANFDISVAAYPEVHPEAKSAQSDLIYLKQKVEAGANRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVTNFKQLQKMAKITNVKVPHWMHKMYEGL
DDDQTTRNLVAASIAMDMVKILSKEGVKDFHFYTLNRSELTYAICHALGVRPT
>A0A8D9X5E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella ceti M644/93/1|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A8B7LFN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila elegans|TrEMBL
MKDQSFMRMQTMVSNDIHDHFHSGSNGGFNLSPDIFKEKLDAVGTLSTVLRLKRNTDLIP
AAHLTCVGAPREAVDDLARCYRDAGVHHIVALRGDPSAGAVDDSPRPGGYTYASDLVAGL
RRIADFDISVAAYPETHPTALSPEADLDNLKRKLDAGGTRAITQYFFDSEIYLRFLDRCL
AAGITAPIIPGIMPVSNYEQIVRFSAVCGVTVPAWLRHLFDGTAKNPELRRIVASMVAVE
QIRTLQTYGINEFHVSTLNRADLTYAIAHILGVRPMQTNASHNVTGLLEKTEVSDERETP
ADFDSTAWAQEGAPPFMLRTLFG
>A0A7W4TK38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineococcus radiotolerans|TrEMBL
MTLAPLVAGAAGRPVLSFELFPPRSESAREGLWRKLSDLLAARPDFVSVTFGAAGATRGP
SRDLLAHVLRTTAVPAMAHLTCVGSSRREVVDLASEFLDAGVRNVLALRGDPPAGDAGWT
PHPDGVATARDLVELLQVADRRRAALRGGRVPVDEGPLSLAVAAFPRGGEGELAALRAKQ
DAGADFAVCQVTFSAGEYAAFVRRARAAGVRIPLLPGVAVTDCTRRLGRIGELTGVPVPV
PLLAALDTDDAPRRRRAATAFTAGLARGLLDAGAPGVHLYTFNAAEPALDLLDDLDLPRS
LDPIRASTAAAAGGPAR
>A0A844G2M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Victivallis lenta|TrEMBL
MLYFIYLITKKQPNWNDTMNCLQRKLAESLVIFDGAIGTEIYRRNFFVNASFEQLSVTNP
DVILDIHRQYLDAGAEVLTTNTFNANARRLGKFGLADQTATINRASAELARQAVREAGLE
GSVLVAGSVGPIGEPESAADTRSRDSILVEQLEALAPVVDFIIFESLRTTIDLAAALEAV
KAFPELVYVLSFAVDRHAENHSGDGISEFGRLISTFPGQRPTAIGLNCGGGPESTLGELE
ILVKRTKLPVIVQPNAGQPRGVDGRMIYMTSAEYFSTYAKRYAMLGAAAIGGCCGITPAH
IRELARTIKPLMRAEKQELPKVEIVECDLKEPVPLAEKSSLGAKLAAGKFVTSVEITPPR
GFDLASTVAGARKCKEAGIDAVNLPDGPRASARISPFAAAVAIQQQVGIETVLHCCCRDK
SVIGLQADLLGCAGMGINNILFITGDPPKLGDYPFSSGVFDVDSIGLVKIQSRMNRGIDL
GGKSISAPTRAVIGVGADPSAIDLEREYRRTCEKVEAGAEFIITQPVFAIETLFAFLDRI
AHLKTPLIAGIWPLVSYRNAEFMKTEVPGVVVPDAVMKRMAAAGTKEEQREAGLEIARES
IAAIRDRVQGIQVSAPFGNVDLALRVLK
>A0A1G0N271|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium RIFCSPLOWO2_12_FULL_68_9|TrEMBL
MTRSLRDLIEDGRVHVCDGAMGTMLYSKGVFVNVCYDELNLTRPTLVQEVHEAYVRAGAE
LLETNTFGANPVKLAGYGLADRTEEINRAAGQLAKKAADGRAMVLGAIGPLGIRIEPFGP
TSRDEARAYFVRQAAGLVAGGVDGFILETFSDLEELHQALEAARATADLPVFAQMTVSED
GSTAFGTDVETLARALTAWRADVVGLNCSTGPAMMLDAIERMAPVTDRPLSAQPNAGLPR
AVGDRSIYLSSPEYMATYARRLIAAGVRFIGGCCGTTPEHIRKIRDVVGDLAPRHPSVVS
ARGTVTPPPGVSPVPLGERSQWGASLARGEFVTTVELLPPKGWLPAKLIEQGRALKAAKV
QAVSILDGPRARSRMGSIPAAIVLLREVGIEPVIHYTCRDRTMLGMLSDLLGGAAAGLRN
ILIVTGDPPRMGPYESGAVSEVDSIGLTNLVYRLNHGLDPGGNPIGEPTRYVIGVAVNQA
ATDVERELSRLHWKVDAGAEFAVTQPVFDVDQLAQFLKSAERYRVPVVAGLWPLVSLRNA
EFLANEVPGINVPERVLARMRTAQEQGADAALAEGIAIAREVKEAVKGLVQGVQISAPLG
RVDVALQVAA
>A0A6P8WMC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila albomicans|TrEMBL
MCFNLSRILSHTTFLRSMRTIKRNQYHSHCKYHWMFAKRLCSSEANASAIKPYFEFTDDQ
KEHCLNDPNIAEIVKEKSKRKEFFYGIEIPLKMDLNTCLDFKMFLPQMPEFMSIVWTKQF
SDAIRSASMAKLPNIQTVSHLTPFIPAMAHISLHRLTQQHLNDFLDLNLNNVLVIRGDHV
EEGQEYNYAYEAVKYLRAARGNRLAIAVAGYPEGYTNLQVGPRNKALDIEYLKLKIDIGA
NLIITQLCYSAEKIIELIKDARIAGITVPILVGIIVPYSFSNYQIIERITGVRLSPEARI
EVEQLSSDDTKVKDYFVQLMVRIIQQILEADLGIYGIQFFTLNHFEPVVEVLRELRSKGI
PKNSKADC
>A0A371B099|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerosacchariphilus polymeriproducens|TrEMBL
MDIREYLKKNRLITDGSMGTYYESLAGEEDSIVERANANNPVQIKKIHLEYIKSGARLIR
TNTFATNSMFFQTEQEIVSNIKAGYSIAKEAVKESGENVFIGADIGPISEEQSREYEETV
NEYKLIIDSFLEEGASIFVFETFSELNAIQDVTEYIKEKNPEAFILVQCAFDRSGYTKLG
LSLKRMVKILGNMDSVDAYGLNCGVAPTHMFEFFQRVEFPNDKFITALPNASYPVALRGK
TVYSDNVSYYVEMLQRIDTLGIDIIGGCCGTTPKHIQLLVQKLKDKQRSKKKINKDLAAG
VEVNNKTTIKNEEENHFIKKIRSGEKVFVVELDPPFDQDDRKVVDGARILKEARVDAITL
SDSPLARARADATHLAVKLQNEMGIPVIAHMTCRDKNVIGLRSILLGSYINNLRNFLFVT
GDPIPRGERDKIKSVYEFNSIKLMEYVKSMNEDLFLNQEISYGGALNYHGVNLDNIAERM
KKKMEAGAEYFLTQPIYTKDDMERIQELKVKTNGKIICGIMPLVSYRNASFIKNEMPGIN
VSDEIMEQYKPEMSKEESEETAIRISVGIAKQLYESADGFYFMTPFNRVYLIRTILEEIR
KFNV
>A0A367XLI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida viswanathii|TrEMBL
MATVSERISSLKPDERFVSFEFFPPKTDSGFRNLLARLNRMLAFNPLFITITWGAGGSTS
EKSLDLAATCQKEVGITTVLHLTCTNTNKEIIDEALARAKANGIRNILALRGDPPRAEEY
WTPNCDFNSAVDLVKYIRQQHGDYFCIGVAAYPEGHVDGADTSGQDPKKDIPFLIEKIKA
GGDFIVTQLFYDVDKFIAFEKLTQEHEELKNVPLIPGLMPITTYKVFNRAAKLSHASIPR
EISQQVDRVSNDDDAVKALGVEILSDIIDKIDKQTRIKGYHFYTLNLEKAVASILDKSKV
LRPILDGPSSVVEHEDAIASDSEDEEETPSTAVNRRRSSVNDNILNGAKVLVGKTLLKDK
KVLVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHSRAEAEIKWGSP
ETVGDLAQIFIDYLSGKIDVIPWADQTLSPETALIQEELFLLNEKGWFSVASQPATNACK
STDNIFGWGPRNGVVYQKAFVELFMPKEDWQKLKPLVKASDSITYYIGDKTNKIETEVPI
GHNARLSKNAVTWGVFPLKEVVQPTVIDYESFKAWNEEAFLLWLEWSRCYKKSSKSFELL
NNVYENYVLVCLIHHDYLEEHALWDFLLHE
>A0A211ZNN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Inquilinus limosus|TrEMBL
MTTNISHANASAEAGRRDPAAAEIGRHDPIVSFEFFPPKSEAAEATLMETVTRLAPLAPD
FVSVTYGAGGSTRDRTFGIVTRIQDGSGLPTASHLTCVGASREEIDGVARALWAAGIRRI
VALRGDPPGGAPYQVRPDGYAYAADLVAGLRRIADFDISVAAYPEVHPAAPSADFDLDNL
KRKADAGADRALTQFFFDTEAFLRFRDHAAAAGIGLPIVPGILPITNFARTKEFATACGA
AVPDWLEMLFEGLDETPDTRQLVAASVAVEQCRLLQTHGVEEFHFYTLNRAELTLAICRF
LGIRPRRAEACAA
>A0A2A6PDP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. BJ1|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMEVQLFQTVADLSIFAPAFQTVTYGAGGSTKAR
SLTTVKRMIGEMGLQNTAAHLTCVGAPKTEVDAVIDEFVACGVRHFVALRGDPQGGIGSA
YQPFAGGYESSAALVKALRARGDFEISVSAYPEKHPESSDVAADIDMLKRKVDSGATRAI
TQFFFDNDDFERYLERVRRAGVHIPVVPGILPINNLTQVIRFAGLCGSKVPEAIISRLAH
LDDQPEERFKEASHIAAEQIVDLARRGVRDFHIYTMNRSPLIAAVCDLVGYARRPAKRAT
VSSYRAVATA
>A0A2Z3X0J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. CRE-46|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A429D6Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. WAC 04169|TrEMBL
MDLVRRIDRAAGEFLLFALTPPRLATAHERVQQIADATMARLRPLNLDGLILYDIDDEAA
RNPARRPFPFVPTLDPANYLADNFTSWQTPVIVYRAVGKYAPSELRTWLAAQDPARVMTV
LVGASSSKIDTMTSLADAQALRREANPGLSLGGVAIPERHSRRDDEHHRLLAKQDAGCRF
FVTQVVYDVNAAKNLVSDYHYECVARGRAPVPIVFTFSVCGSLKTLDFLRWLGVDVPRWI
ENDLKHAADTLEASYQLALAAATELMTYCRGLGVPFGINVESVSIRREEIEASVRLAERL
RAEIKG
>A0A0T7E800|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio coralliirubri|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELVQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A4P6FZ07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas arsenicoxydans|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKTAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A2A3BU11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM4308|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVGRILNETSLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKEAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A1I3B2C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium levicorallinum|TrEMBL
MTTTGISACNARPAFSFEVYPPKSAAAASALMSTIDHLAAAGPEFISVTYGANGSSRNSS
LDLLRYIKDHTEADAMAHLTCVGSSHAGASRLIREFLDAGIRSFLAIRGDAPQGAVEGDN
TFLGDLHSAGELVQLIHRVQTERVPYIETVIPGLPGARGVKTERSKVRIGVAAFPNGHPN
SRSVSQDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLFPILPGIMPVTSPN
RLRRILQLSGEKLPADLSIDLEVEPTEEGQRQIGIDYAVRLGQDVLAGGAPGLHLYAFNQ
HDTVLQVLEGCGALPVPAVML
>A0A1C3JTU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinomonas gallaica|TrEMBL
MTLPLPKFSLETTGKSVQELSTVADLLPPHTPVNIAFLGNETHQQRIQAAVTIKALGLEP
TPILSSRRITSKADLDYLVGELKYRADIKRLMFVGGDPVVPEGPYENSLALFESNILKTC
DVETIVIAGYPEGHPHITSDQLMAALKWKIAFLRKNHYKIEITTQLAFCTTRIIKWVQDI
RAVGIMEPIRIGVPCPTKVKTIRYFANLFGVPITADALAHYEMDIADEQLDAKTDSLFLE
LAQQIERLGIKNIYFHLYTLDGVSKNTSWIQNHL
>A0A139IIK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudocercospora musae|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFSNLNARLSRMAHSLRPLFVNVTWGAGGST
STKSLALAELTQRELGLTTCLHLTCTNMSRKLIDEALEQAKVLGIRNILALRGDPPRSEE
YRDDHDKEAAEDDSNKDFTWAVDLVRYIRKQYGDYFCVGVAGYPEGHSDQSHPEHQSVEH
DLPFLVEKTKAGADFIMTQLFYDVDAYEKYENTLREHESGVFKTIAIIPGLMPVQSYQIL
RRTAKLSHAAIPSDVSKRFEAVKGDDEAVKKVGVDIISEIVEKMKGIGRIPRARGFHFYT
LNLEKVVAQILERCNLIPPSTPGVVTSGSTEDDEAVAVEESDDFVLVENAKKKDHRRKSS
IANSQPRNRIIVSHIRASSTTSNRASSTSAFEARDDEAGVPKEKINSRANILAISEGEGA
LGREATWDDFPNGRWGDARSPAYGQIDGYGVSLHVSAPDAKRLWGEPVKAEDISTSFRRH
LEGEIDSMPWSEESLQPETVTIKNELLQLINRGWWTVASQPAVNGVRSTDPVFGWGPKNG
FVFQKPFVEFFIPGAEWKKLQFKLEEHPQITFFAGNAQGDFVSSDEDSVNPVTWGTFTGK
EIITPTIIEAVSFKAWCEEAFGIWGEWQRIYKPGSESSKLLERIRKDYWLVSVIHHGFLE
KGALWNDLLEE
>W9WLR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cladophialophora psammophila CBS 110553|TrEMBL
MHISKKLALAHQQNKPTFSFEFFPPKTAQGVQNLYDRMDRMHNLGPAFIDITWGAGGRHS
QLTCEMVNATQNYYGLETCMHLTCTDMERHQVDEALRRAYKAGCTNILALRGDPPRDQEK
WEAKEGGFRYAKDLVKYIKARYSDHFDIGVAGYPEGCDDQRDVDLLIDHLKEKVDAGASF
VITQMFYDVDIFLNWVKKCRERGINVPILPGIMPIQTYAAFVRRANWTKCHVPPEWFDAL
EPVKNDDAAVRAIGKDLVADMCRKILDAGILHLHFYTMNLAQATRMVLEDLSLTPETSGL
RLEKPLPWRQSLGFNRRDETVRPIFWRNRNASYISRTADWDEFPNGRWGDSRSPAFGELD
AYGTGLKGTNEANIKLWGKPRSLRDVTTLFVRFLQGTLDRLPWSEGAISAEADSIKDDLV
KLNKHGFLTINSQPAVDGASSTHPVYGWGPAGGWVYQKSYLELLVFPSMFKTVMERLNTN
KNLTYYAVNRKGELYTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WAKCYPAGSGSRKLIEKIMDECYLVNIVNNDFHQNHEIFELFEGLEAQDLDAVVEDTVAD
HPGNGTRDVSNGDASVTGAEKSVTNGEQNKVPSKASGEALTN
>A0A2N2FC22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-9|TrEMBL
MFIRELFRQKRFTLSFEFFPPKREGNLDGLFATIQELSALKPDFISVTYGAGGSTRERSL
EIASRAKKEFQTEVLAHLTCVQSTKDDIARILEAFRAENIENILALRGDPPAGTEKFIKP
ESGFSYASDLVAFIKGMDFFSIGVAGSPEGHIEAPSLVEDIRNLKRKVDAGADFIITQLF
FDNHFFYRFRDRTLAQGITIPILPGIFPILNYKQVERIAGLCGASIPQALANKINKVRDK
NEEVEKYGIEYATKQMEDLIRNDVAGIHMYSMNRSEPVQCILKELHLPRSPR
>A0A6J0SVX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pogona vitticeps|TrEMBL
MVNESYGAPLAAVSEGLASARPDGLGVGGGGSSSSGGESSKDSSRCSTPSLLDAERQDRL
WEKMRRRQEAGDKWFSLEFFPPRTANGAVNLISRFDRMGVGGPLFIDVTWHPAGDPGSNK
ETSSLTIASTALNYCGLETVLHMTCCNQTRETITAHLQKAKRLGLKNIMALRGDPVGEEW
QEEVGGFNHAVDLVKHIRREFEDYFDICVAGYPKGHPEAESYADDLRHLKEKVSAGADFV
ITQLFFRSETFLQFLRDCQAVGITCPVVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIE
PIKDNDAAIRNYGIELAVTMCRELLDSGLVHGLHFYTLNREVATVEVLKRLGLWKEDPRR
PLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYL
FYLKSKSPRDELLKMWGHELTNEESVFEVFRCYIAGEPNKDGHKVTCLPWNDDPLAPETN
LMKEELAKVNLRGILTINSQPNVNGKHSTDPIVGWGPEGGYVFQKAYLEFFTSSETVRAL
QTVLKRYGQRVNYHIVNVKGENITNAHGMQPNAVTWGIFPGREIIQPTVVDPVSFMSWKD
EAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLDSCLWRVLEDTFELLNG
PAEE
>A0A6I5BC04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4941|TrEMBL
MHPLDTASAAVGTSLLEDFSLEMTGKDVPELEAADGTLPRGTRVNVTFLGNEDPRMRLDA
ARAVKRLGLLPVPHISARRLTSRTDFEQFLAGLRDDGTATHVFTVGGDPALPQGPYDSAL
ALIDSGLLQEHGVRHVGIAGYPEGHPALTDDTLRSALRDKAASLTAHGLTGHVTTQFGFD
PDPVLSWLEDIRDQGITLPVRIGVPGPAGVRRLLSYATRFGVGTSASIAKKYGLSLTNLM
STTGPDAFLRTLAERYDPARHGEVKIHFYTFGGLRATAEWIARFRQDNHV
>A0A7X5N1D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas perforans|TrEMBL
MTPLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAIT
>A0A7C1FDS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ammonifex degensii|TrEMBL
MWISEIFATRKPVISLEIFPPKTENRADIASKLAADFQPLQPAFISVTYGAGGTTRDTSV
ENASLLSGLGFTVMSHLTGIGHTTQEIDAIAAQLEVAGIENILALRGDPPKEMTKSGFTF
GDFAYAVDLIRYLRAKGTFCIAAAAYPEGHIASPRVDLDWRYLKEKVDAGAEFLVTQLFF
DNRVFYHFLESIRRMGIFCPVTAGILPVIDAGTVKRIVSFCGASILAKVLEMLDRYSDDP
GSLAKAGLEYATAQVADLLANDVDGVHLYTLNRSGWVVKLLRDIGYEPRVHIPETWEARL
PEGWDHPSPL
>A0A5F1EQC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E4702|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3D1KZY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prolixibacteraceae bacterium|TrEMBL
MKVIDIIQNTGKTVFSFELLPPMKGNDAGKLFQTIEGLTEFDPKYINITTHRDEVEFKEM
PDGSIVKRTVRKRPGTVAIAASIQHKYGIPVVPHILCGGFTKSETEHVLIDLNFLGIKNV
LALRGDGVKGQHVFQPEKNGHANANLLVQQIKDLGQGKYLEDDLKNNAPLDFCIGVAGYP
EKHFEAPNMEQDLLYLKQKVDAGADYIVTQMFFENRDYFDFVKKCREAGINVPIIPGLKP
INLLNQLTVLPKIFSIDIPMELAKALAQCKTNDEAAKVGTAWTIQQAKELVKQNVPSLHI
YTYGVSDNVKEIVKAVF
>A0A0G9B0U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas perforans|TrEMBL
MISTDTPNFASTVTEAYSLEVSAKDIGALTNAAPRILPGCAMFIPYLPGQNEAVRLAAAQ
RVRRLGFEPVPHLSARRIGSLEELQACVARLVDEAGVTRCLVIAGDPSTPKGPFPDSVSL
IETGVFERSGIGTIGVAGHPEGHPILRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
IVVTWLEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLASRLTQAHGDVRLHLFPFGGIAQSVQWVAHYHSRNASQDRTSAVRADRA
>U4PU70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium pusense|TrEMBL
MHTLPDISATSVIPASIEASPAQVLGPASLAGLFPQGVRVYLTDTGAASQVKLVDAAKHL
RDLGYEPVPHLTARRIASRIDFEEQVKRLAGDAGVTDVLAVGGGVEKPEGPFTSTIDMLS
TGIFDRCGIRHIAIAGHPEGSPDFNDETATAALRLKRDFGEKTDAAMRIVTQFGFDSARF
IAWAEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTTLARGHS
PESIVGPIERHWRDNPQGPIRQIHVFPFGGLQASSDWLVSRGSWRTENADHAAATGSVAI
>R6NTC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudocatenulatum CAG:263|TrEMBL
MHSPMFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVS
EYGIPSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFEHASDLAV
YIRQQRPDMKIYGACYPEKHPQSATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KARAAGIDVPIEAGIMPVMNAKSVLNMSNKCQSKVPEKLGIMLDKWGGDKALLKEAGIAY
ASEQICELVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A2S4YSY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ru71|TrEMBL
MGATPTLSFEFFPPKTAQGEQSLWQAIRRVEPLAPDFVSVTYGAGGSSRHRTIEVTKRLV
SETTLRPVAHLTAVGHSVAELRRIIGQYADAGVRDVLVLRGDPPGNPKGPWEPHPDGFMY
AAQLVELVRSLGEFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFDVEDY
LRLRDRVAAAGCDTPIIPEIMPATNVRQIRRFAELSDAAFPEDLAHRLEAARDRPADAYA
IGVEHATAMAQRLLAEGAPGLHYITLNKSTAALDIHRNVLGSRSLQVG
>B2PVJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia stuartii ATCC 25827|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRTEEMEQTLWKSIDRLKNLKPKFVSVTY
GANSGERDRTHSIIKDIKEKTGLIAAPHLTCIDATRDELREIARDYWNSGIRQIVALRGD
LPDNSRKPDMYAADLVELLKAEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPSWMSRMYE
GLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A4V1QS43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces binzhouensis|TrEMBL
MTGTEPDGVAARPRVPISFELFPPRTDAAAIALGRTIDRLAEVDPAFISVTFGAGGSSRD
RSLTVLRYMLEHTSVEPMAHLTCVGSSHAEANRLVREFLDAGITSFLALRGDPPAGAADA
EDAIGDLHSAAELVQLIHRVQEEREPFGQSRIPGMPGVTAIRERPRPERVAVAAFPTGHP
RSRGSNQDVDVLLAKEVAGANLAITQLFWHADDYLAFVQRARAGGVTIPILPGIMPVTTP
ARLARLEQLTGVPAPAALAIDLEIEPDADAQFELGVGYAADLAAGVLDGGAPGLHLYTFN
RHEAVLAVLDRLGLATAHAHAGTERNTRER
>A0A2R7S9E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelomonas sp. HMWF004|TrEMBL
MSTPVSFEFFPPNTPVGVEKLKTVVQVLGALQPQYFSVTYGAGGATRDKTLSAVTDIAAA
GFNAAPHLSCVGSTRLGLAEILSTYRAQDIRRVVALRGDLPSGTATAGEFRYAAELVSFI
RETQGADWHIEVAAYPEVHPQQRYAAKDLQHFADKMKAGADGAITQFFFNADAYFHFVDE
ARKLGVTQPIVPGIMPFHNYGRIAQFAQRDGIEIPRWVQMKMEGFMDDAAAIQAFGLDVV
TRLCERLIQGGAPGLHFYTLNQSPLVLALCQRLGLASKA
>F4P4P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211)|TrEMBL
MKVVDKIQKANDEGRCFWSFEYFPPKTESGVVNLFDRMERMYLLGPEFIDVTWGAGGTTS
DLTLEICTTAQAVFGLETCMHLTCTNMPRIKIDEALEQAKNAGIMNILALRGDAPRGQTN
WTKVETGFSYATDLVRYIREKYGDYFCIGVAGYPEGHTETPDKEADLLYLKEKVLAGADY
IVTQLFYDVDIYIDWSKKVRAMDITIPILPGLLPIQNYSGFKRMTALSKTFVPQFILDDL
EPIKDDDQAVKDYGIRLAVQMCNKMREAGQRGFHFYCLNLERSTRLILEGLDFVAPRENV
KPLPWNPSLGKNREKETVRPIFWRNRTKSYIMRTDGWDEFPNGRWGDSRSPAYGDIDGYG
IRLKYSAEDCLTFWNHPETLGDIYGLFEKYCMGDLSCLPWSDTPLFPESEILRARLANIN
RSGFLTINSQPAVDGALSSDSVYGWGPKNGYVYQKAYLEFFISPKKLDLLLEKLCQHPFL
TYHAVNKNGDLKTNTKNDSPNAVTWGVFPGQEIVQPTVVEGVSFIAWKDEAFELWKQWSQ
LYSAESPSYKIINHVTSNWFLINIVDNNYKNRFAIYDILDQVAADAKDIIDH
>A0A263DEE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. MH-G8|TrEMBL
MSAEQRAASPAADDRHLQLLNEATMEVIPLKGAQDQILATPEDATVAVTCSPKFGLRRTL
EYCALAANSGRRVVPHLAARMVTDRAALRDFVQRVADLGVTDLYVIGGDAATPVGRYHEA
AAMLDDLSSMEHPFTRIGIGCYPEGHPNIDDDRLWEALLRKQDWATYMVSQMCFDASTLT
SWLTQARARGVTLPIRVGIAGPLKLAKLTELSLRIGVGPSLRFLAKQHGLVGNVLLGRTY
DPAPLVRALLAAEPRPGGDIEGLHVFTFNQVPVFRAWIGTQGGATA
>A0A263DF12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. MH-G8|TrEMBL
MRAALAAGRFAVTAEIGPPRGADAAAVDRKAALLRGWVDAANVTDNQGAHVRLSSLAGSV
LALRAGVEPVMQLTCRDRNRIALQSDLLAAGALGVPNVLLLSGDHPVYGDHPDAAGVFDL
DSLQLVWTARTLRDEGVLLSGRPVEKRPEFLIGAVENPFAPPTAFRAIRLGKKVAAGAEF
CQTQFTFDVPAFARFMAEVVDRGIAQRCSVLAGVGPIRSLRAYEFVRSQVPGVHLPESVG
RRLRGVPGDRVAAEGVTLCVETIEELRAIPGVAGVHVMAFGYERGIPEILERAGLGHPSA
PAAPTERKERA
>A0A856Q1J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptacetobacter hiranonis|TrEMBL
MGRLKDSLESGKFTVTCEIAPPKGTDISHIMECIEVLKGKVDAVNVTDFQSAVVRSTSLV
TCKILKDNGIEPILQMTGRDRNRIAIQGELLSAGIFGIENLFAITGDHTSKGDHPQAKNV
FDLDSINILKAAEYISFGRDMNHNELNGHPKFYMGAAVSPGFVPIEIQIIKMIKKIAAGA
KFFQTQAVFDIETVREFRKRTKNFECKVLIGVIPLKSPGMARFLNRNIPGVDVPENIIER
MESVGKENYKEEGMKIAAEFIKQLKEEKLCDGVHIMSVGAEKNIPKILEMAGIEI
>A0A7X6G2U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium R_SAG6|TrEMBL
MTTPEISFEFFPPKNLEASFRLWDTVQSLAPLAPRFVSVTYGAGGTTRELTRDAVTTLHK
NSGLKVAAHLTCVSATRQETLDIADQYAAAGITDIVALRGDPPKEQGRFTPTEDGFGSSV
ELIEALAAKGKFNLRVGAYPESHPEAASQQANVEWLKRKLDAGADEALTQFFFEAESFFR
FRDACAKAGIDTDRITPGILPIENWKGVRRFAEACGTTIPAWLDEAFEKAQRDDRCDLLA
TALCSELCTELLDGGVKKLHFYTLNRPELTRDVCHALGVKSKARLQNVA
>A0A8J3LHZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catellatospora methionotrophica|TrEMBL
MSDDIAPARTGRPSLRAMLERAESGVLLLGITPPRRSVSPEQAAQIAEVTLARLATVDLD
GLILYDIDDESDRNPAERPFPYLPTMDPAAFHREHLDAWQLPSVIYRCVGKYTEPEFADW
LGEVDADRVLSVFVGASSKDKGVRTGLTQAYAMRDRLRADLPLGAVAITERYLRSGDEHL
RMLTKQDRGATFFITQVVYDVDATKSLLSDYYYTCAQKGVAPRPVIFTLSVCGSLKTLSF
LHWLGVNVPRWLENALRYSDDPLTESYQQCLATARELAAFCGRLGVPFGFNVESVSIRKV
EIEASVELAREVRELLRG
>A0A837C9N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium diazoefficiens SEMIA 5080|TrEMBL
MTDLTKPATADGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYGAGGST
RERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPPGGIG
TPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDAGAT
RAITQVFFDNDLYFRYLDRVRARGINIPVVPGIMPMHNFKQARAFVTRAGTSVPDWLAEK
FEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAKSAQ
KAA
>A0A8J6NJN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfolinea nitratireducens|TrEMBL
MEGLEMPLFTPGRRYQLPYLPSKKKSGQSYILEPIERMIKGPLFACRMCGNCLLQETAFV
CPMACPKGLRNGPCGGSTSEHCYIDPSYPCIWYEIFDRAKKMDREEMLLEVLPPLDWDIV
GEETWGEVVRKVKETGTKTFFGSFFKKDAGERKQIWDSVFKSIRQPDWWQGDDQYHPPGY
EEPVSELERQLRSGKFVVAAEISPPASTATGKLLRDIELIKQYATSINFTDAASATPRMS
SLACCEFALEAGAEPVLQIAARDQTRTGLQGHVIGASARGIRNVLVVSGDSARLGPKPMS
RTDILDIDSVQMLWILRRMRDEGIYLGGREIKNPPQIFLGAAAAPFASNPRIQAIREHKK
VNAGAQFFQTNLVFDPDGLELWLNELAKRNILDKVYILIGITPLRSLKMAQYMHNQVPGV
RIPDQLLKRLEDAGDGVEEEAVIIALEIIEAIRNKEGVNGIHLMPVGWEQVVPRIVQELD
GAKVVASSS
>A0A2T3R082|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium kishitanii|TrEMBL
MINQDLVTNTESELRVRYNDITRGVYFIGTTPPKTNTPLDEVETIADRLVNRIKDLAIDG
LIVYDIQDEVSRTKKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSETDAFDEWL
NEAWHEYQVRDIVLVGSPSAKNEVSLPLSAAYQALAENKNNFFTGGIMIAERHAKKGNEH
ERLIEKYQQGCNFFISQAIYDTQATIDILTRYAIECKQDGIKPQRILLTFSPCGSAKTLE
FIEWLGVSVPEATSLRILNATNPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRK
EEIDGSILLYKLLRASMDSHLAKHEFRMLQKNTITAL
>A0A182JUH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles christyi|TrEMBL
MVDHLATTNSVTEEENSEDVLYAKLDHIFNSSTQAIPVRYSIEISSKDDFDIGQLERLTP
QPVFSALPWISDENLRYADNFSRSPTLQLTNRLRKSRYTVVNHVSCYNITEQQVDQLLST
GIRNLFVIRGDTVSPEQTFLNSAGLVQYLRKQEQQKGHSKLTIGVGGYPYGHHQSPSETD
ELRYLAEKISNGVDFLLTQTVYDAQSFLRYRTRCREAGISIPIIPGIYVPHSYRHLQTML
NLTRIQLRPTVRDAFDTHANDAPEQFEAFMVDYFVGVLRELLEPNASSSDPIKLVHFFTF
NKFALLQQVLHRLENFIE
>A0A6J1I4Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cucurbita maxima|TrEMBL
MKVIDKITEATAGDGGRVVFSFEYFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGS
TADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQ
DKFVQIEGGFACALDLVKHIREKYGDYFGITVAGYPEAHPDVIGSNGVATTEGYQSDLAY
LKKKFDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTSFCK
TKIPDEVMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHMYTLNMEKSALAILM
NLGLIEESKVSRSLPWRRPTNVFRIREDVRPIFWANRPRSYISRTIGWDQYPHGRWSDSS
NPSYGALTDYQFMRPRARDKKLLEEWALPLKSIEDVYEKFMKYCLGKLRSSPWSELDGLQ
AETRIISEQLGKINMKGFLSINSQPAVNGERSDSPSVGWGGSGGYVYQKAYIEFFCSREN
LDAVVDKCRGLPSLTYMAVNKEGIWVSNITQNDVNAVTWGVFPAKEIVQPTVVDPASFLV
WKDEAFEIWSRGWASLYPEGDLSRKFLEEIQSSYYLVSLVDNDYVNSNLFAALEGF
>A0A2S7D3T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas pisi|TrEMBL
MDPDTPSLADTITEAYSLEISAKDLAGLATAAPRIMRGSTIAIPYLPNQDDDARLAAARM
VRALGFQPMPHLSARRIASREQLHAFVRRAAQEAGVERCLVIAGDPPAPLGPFADSLSLI
DTGIFEDSGIRTIAVAGHPEGHPTMSTSERLEVLDRKCRSIAERGMAPLIVTQFAFDADI
VLAWLEALRARGIAHPVRVGVPGPAGVAVLARYAASCGVGACASMLSKYGISFGKLLGTA
GPDRFVERLATGLTDAHGEVRMHFYPFGGIAQTVAWVEQYRSRSAHV
>A0A2D0IWH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus budapestensis|TrEMBL
MSFFHANHQEALNQNLAELEGQIRVSFEFFPPRTIEMEQTLWKSIDRLSKLKPNFVSVTY
GANSGERNRTHSIIKGIKDKTGLDAAPHLTCIDASREELRDIARDYWKNGIRHIVALRGD
LPDGSCKPEMYGTDLVDLLKKEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFAAITNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A192IQM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium NRL2|TrEMBL
MPTGLDRLDFSFEFFPPKTEAGWRGISRAAAAFQPLDPEFCSVTYGAGGSNQTGTLDAVL
AVQEASGSPGAAHLTAAGQSREAVDAAARTFLDNGIGRIVALRGDSRDEGPYRPHAEGYA
NAAELVAGLKKIHDFDISVAAYPEKHPDSPTPEADLENLKAKLDAGADRAITQFFFDADS
FLRYRDRLAAAGVYKPVIPGVLPIRDIEQVQRFAAQCEAVVPPMVVAAYDGLEQIEDRRK
RSVDLAHELCARLVRHGVRSFHFYTLNKSDLTVEICKRLAGTAESEAAVAAASAAR
>R5DYY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:108|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISSLKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKD
FTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A0Q7QJC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root140|TrEMBL
MDQQSPRGIGQLIREGERSFSFEFFPPKDEAGEAQLWQAIRELEPYRPTFVSVTYGAGGT
TRDTTVAITARIARETSMVPMAHLTCVGHTVDEIREVLKSLTESGVRNVLALRGDPPGGP
GTAWEATEGGVNYASELIGVIKEIADVSVGVAAFPEGHVDAASLDDDVAVLRAKQDAGAE
FAVTEMVLRAADYFGLVERARATGVEIPIIPGVMPILNINSMRRMVELSRRELPTEVVDR
LRPFEEDPAGLRAEGIRIATELCEAMLDGGAPGLHFYTLNRSKATREIFEGLRITV
>A0A4Q5BW74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. bf_0095|TrEMBL
MTKQTPSLSFEVFPPNPEVGNAKLLRALENMQELAPHFISVTASNNKYNIKETTVALANH
IQNELSIPTIAHLPAIYLSKEKVADTLHELDQVGVHRILALRGDIIPGIEPLKDFRYATD
LIEFIKTEAPHFDVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVHHATKALFEHQPNLEVI
>A0A1I8GKA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
MPENSSSVAKMPAKEKLQQEEQERPQSPQPPSSRQYRPLATRIRRRIEKGRRWFSCEFFP
RAPRRPLFARGRPLFCDVTWHPAGNPAGDSPTSSTSVASAMLNYCGIDTVLHLTCVGQTE
ARLVRVLDRAKSLGLKNILALRGDLPEDADGNPGGASAAASGGPAFASDLVRLIRRRYGS
FFCIGVAGYPAGHPEAASYAEDLRRLKEKVDAGGEFIITQLFFESAEFLRFVSDCRRGYQ
SLRHIVKLSKLTVPDSMLRVIEPIRDNDEAIRNYGIAQCTQMCQELLQSGQVHGIHFYTL
NRDAATIRILKNIGLWREDLPRPLPWQPSANYERCAEAVRPVFWSRRPTSYVHRTRHWMT
IPTAGGAPTQPHVGQRADQRAGHGGWRVFASHLSGNQSPESRLPWGDEEPLPPSSESNEA
AEARQRLAGLSERGLLATNHLLRVNGASSDHPVHGWGGSGGFVYQRAYLEFFLPGRRLPA
LQSALSSHGGGRVSFHIADRSGNVNLANFSEPIALTWGVFPASEVAQPTVCDGAAFLAWR
DEAFALWTEEWGRLYEEGSPSRRLIESVAETYLLVALVDNDFTEDSVLWDLTDQVARAAD
GSDEVELA
>A0A1I2UBS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oribacterium sp. WCC10|TrEMBL
MKIIDILNSGKTTLSFEVFPPKKIENFDSVQQATEDVAALKPSFMSVTYGAGGGTSEFTL
NIAKNIRDKHGVEVLPHLTCVSSTKEHVHNMLTKFKENGFENIMALRGDIPKDGTPHHDY
HYASELIADIKAHGDFCIGGACYPEGHVECAHKDEDIKNLKIKVDAGVDFLTTQMFFDNA
EFFNFLYRLRENDIRVPVLAGIMPITNAKQLGRSVALSGTSVPTRFREIVDKFGDHPEAM
KQAGIIYATEQIIDLIANDVKHIHVYSMNKPDIAEAIQKNLSEILKV
>A0A1I8I954|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
MPENSSSVAKMPAKEKLQQEEQERPQPPTSRQYRPLATRIRRRIEKGRRWFSCEFFPPRT
PAAAVNLVSKFDSFARGRPLFCDVTWHPAGNPAGDSPTSSTSVASAMLNYCGIDTVLHLT
CVGQTEARLVRVLDRAKSLGLKNILALRGDLPEDADGNPGGASAAASGGPAFASDLLLLH
RRGRLPGGPPGGRQLREDLRRLKEKVDAGGEFIITQLFFDSADFIRFVSDCRRVGIDCPI
IPGVLPVQGYQSLRHIVKLSKLTVPDSMLRVIEPIRDNDEAIRNYGIAQCTQMCQELLQS
GQVHGIHFYTLNRDAATIRILKNIGLWREDLPRPLPWQPSANYERCAEAVRPVFWSRRPT
SYVHRTRHWDDYPHGRWGSECAEIGELRDYYLFYLTVRASKQERLRMWGSEPTSEPDIWR
VFASHLSGKPVSPDGVRVTRLPWGDEEPLPSSSESNEAAEARQRLAGLSERGLLATNHLL
RVNGASSDHPVHGWGGSGGFVYQRAYLEFFPARPPAASAAGEPRHHGGGRVSFHIADRSG
NVNLANFSEPIALTWGVFPASEVAQPTVCDGAAFLAWRDEAFALWTEEWGRLYEEGSPSR
RLIESVAETYLLVALVDNDFTEDSVLWDLTDQVARGGRRLG
>A0A352E812|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
EMHPQARNFEDDLANFVRKARAGASSAITQYFFNADCYFYFVERVRKLGVETPIVPGIMP
ITNYSKLARFSDACGAEIPRWVRKQLESYGDDMDSIQAFGTQVISEMCEKLLAGGAPGLH
FYTLNQAEPSLAIWDNLGLSR
>A0A3N5W1B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon|TrEMBL
MDINVIYEMNPPKVLYNNHFDNDTINKNIDLFLLRTKLISEYVDGIHLTDNVLGVPRVSS
LMLVSMLKRMGISKPISCTCRLYDKNLISLLQFVTDAILSGVYSVLILRGDDPVIGNKIF
DVPPTKAIKTLSELNFNNYIKLDLSFPSKIQENVNIKNKLKARPRAFITQSISSIDNLKE
IVSMSTPYSIDVIPCIMCPSTRNEMSAKNIGLDWGSYEEEPENFIREAGNLTDKVLLCSP
NSFEDGLDLVKKLKKN
>Q6N3J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)|TrEMBL
MSDLPQQLPAISFEFFPPKTEEMERNLWQAISRLAPLHPSFVSVTYGAGGSTRERTHATI
ARILKETDLTPAAHLTCVDAPCADVDDVVARYHDIGVRHIVALRGDPTTGLGGTYTPHPQ
GYRSSADLVASIKRRYPDIDVTVSAYPEKHPESTGFDADLDILKAKVDAGATRAITQFFF
DNDLYFRYLDRVRARGINIPIVPGILPVQNFKQAAGFAARAGASVPDWLAKQFEGLDDDP
DTRKLVAATVAAGQVHKLAKHGVSNFHFYTMNRADLAFAISHLLGFRPIAKQKAA
>A0A7G8HMB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. MEDNS5|TrEMBL
MSSALQRSLEAGSITITAEVMPPRGGDPAHTIAMAECLRGRVHAINVTDGSRAVMRMCSL
AVCRLLLDVGLEPVLQMAGRDRNRIALQGDLLGAHALGIRNVLCLTGDPVRAGDQSSVRS
VHELESVRLLQQVSAFNRGEDPVKERLADGPTNLFAGTAADPHCASWSGLSRRLARKREA
GARFVQTQMVMDPRALERFCRHLADPLELPVLAGVFLLKSARNARFINRMVPGACIPDHL
IERLEKAKDPMVEGIAIAAEQVRQFTGIAQGVHLMAVKAEQRIPEVLDRAGVSLPVL
>A0A835X2C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon|TrEMBL
MTIRYEINPPKLPEGEPFSNEDMKKLLDKLKIRVSELSKIFDGIHITDSVLGTKRISPIT
TGEMIRNNQKNLKITISLRVRDKTISEIEKSVNNAIELGFEGILIVKGDKNPKNPEDSKL
IPSQVVKHLKKLGMDNKIELFLSLPTNPNFNKIQNKIDSKPAGFITQVVESVDHVSNLVN
GLKPHNFKLIPIILFPSDKNLKSAEFLNLDWSNYKENVLDFIKNIHNLTGDILITSPNDF
NGVQRTLTKLVI
>A0A5N9DL68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MQPSGSASQHLSAMLENTDRFLTTVEIETSRGILMGEDSRKTMDSAQSLAEFDRVDFVSL
TDNPGGNPHIRPEVLGQELLSRGREVMINLSCKDYNRNSVESRLWALDSQGFSNVLALSG
DYPVGGFEGQAQPVFDIDSVGLIEMMAQMNEGLRNKTLGSSSSGHRLEETNFFTGCVVSP
FKKLEGELMTQYFKLALKVRTGAKFAVTQIGYDSRKASEIHNYVESNGINVPMIGSVFIL
TAPAGRFFNRWGVPGVCVSDNLRDIANRHAKSKDRGRLFFSELAAKQIAILKGIGYRGVY
ISGRPALDRVQQIMELVDSYSKDDWREFAKEIIFSQPGEFYYYEADENPGLSSNTINKDY
ISSRSKYARAKSRIGVPAQYRIGKFVHDRIFSEGSSGFKLGRVVYKQIEKNKMLSDLAHL
AEQVSKVPMYNCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTKAGQCEILDKECIWIR
AYDRMKPYGDEVRMLQGPVIFKDGALQNTSAWGNTFLGRDHHAKKSDAVDEL
>A0A8H6T2P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycena indigotica|TrEMBL
MKITQKISQADKESKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTAEMVKTCQGLIGIETCMHLTCTNMPASKVDIALREAKLSGCRNVLALRGDPPAGKDE
WEAVEGGYVHGIDLVKHIRREYGDYFDIAVAGFPQHQLLPREERDVEMQFLKDKIDAGVN
FIFTQMFYDVQIFIDWVRAVRAAGITVPIVPGIAPIQTWNGFMRATSLASIVIPPSFLDA
LEPYKNDDEKVRAIGTKLVAEMCRKILDENLGIRGLHFYTMNLEKGTKMLLEELNLVPRV
ETVKPLPWRQSLTPNRRTETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGEPTSFQDITNLFSRFCKKELKALPWSDQAPAGETSIIASQLA
RMNDYGFLTINSQPAVNGAKSEDPVVGWGPRNGYVYQKAYLEFFVPPELLSILLTHIERD
SNITYYVINSRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAYELGQQ
WAKIYDVGSPSRQLISDLMESSFLVNVVHNNFHDSEAIFQPFFKAGEEYLATKSGKPQVN
GH
>A0A373CZZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium TF01-6|TrEMBL
MNLREYLKTTNLITDGAFGTYFAAKYQTQDIPELANITATEKVKKIHEEYLNAGAKFIRT
NTFASNTETLQEDFAEVEKNIQAAVEIARDAVNGRDAWIAGDIGPIPVNGAEDAAAAADE
YYQIAKTFAECGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIGEMSLWDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLSVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTKEDAARLRRIKEETGAKILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>A0A0N4TEQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brugia pahangi|TrEMBL
LLRFEALLCGTLFFQFFPPKTTNSVANFFARLDRFREGNPMFVDIAWHFGSDPGNISSET
SSSSVAAGCLDYCGMDTMLHITCCPYTKEQSIRHLEQSKALGLKNILALRGDLPR
>W2E203|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus larvae subsp. larvae DSM 25719|TrEMBL
MRPDLRLALQHQLLTGDGAMGTYLYQLGFPVGISYEELNLLQPQVIADIHRRYYEAGAKI
IETNTFSANKEKLSKFGLEQEVKRINRAGADLARQTVGDDAYVMGAVGSIRGSKRKNVLE
ADVRIAFHEQVEALLEASVDGLLLETFYDLDELLIALRLIRNLSDLPVICQFTTEGNHTT
HDGIPLQEAFERLKDEGADVVGFNCVSGPNGIMQSIGRIHPLEQVPFSVYPNAGIPDYVD
GRIVFGATPEYFAETALRFADLGARIIGGCCGTTPEHIAAISKALRGYVPSAEQAFRLRG
TETGRDEEHPVISTGTAETGDSSYMDGVQNLVDLVKQRPTVIVELDPPRTLDINKFMVGA
KALKDARVDAITMADNSLAVTRMSNLALGALVQQRLNVRPLVHIACRDRNSIGTQSHLMG
MDALGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNKGLAFSGKPLKKKARF
VIGAAFNPNVKYLEKAVQRLEKKIAAGADYIMTQPVYDHALIERIHESTKHMDVPIFLGI
MPLASGRNAEYLHNEVPGIQLPDETRGRMAGLEGEAGRAAGTEMAKELIDTALQYFNGIY
LMTPFLFYDMSVALTEYIWGKTSSRHPLLSRV
>A0A8B9FPJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amazona collaria|TrEMBL
MVNETQHSCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCDQTRDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEDVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFVITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSQTQQ
>A0A139R7Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gallolyticus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADIIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAREAAGDDAFVLGTVGALRGLKQCDLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEAELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKETNFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDELADLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALEHFNGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>D0JBB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blattabacterium sp. subsp. Blattella germanica (strain Bge)|TrEMBL
MKVIEHISKAKKTLFSFEILPPLRGHDIKDIFSTLDPLMEFNPPFIDVTYHREEFIYVEK
ENGLLQRRKISRRPGTVGICAAIMNKYGVDAVPHLICGGFNKQMTENALIDLNFLGIDNV
LVLRGDPLKSEKDFIAKKDGHKYAVELVEQVKDLNRGKYLDKTFVERKESPLFDFCIGVA
GYPEKHLEAPNIESDLFFLKKKVESGADYIVTQMFFDNKKYFSFVKKCRSEGISVPIIPG
IKPISSKKQLNSLPSHFYLNIPNELVKEVEKAKDKKIISHIGIEWAIHQSKELKNFGVEV
IHYYTMDRPENIYKIIQAIY
>A0A524I314|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccus sp|TrEMBL
MSVSMLQEMLDAGRFAVTAEIGPPKSCEPEQVRKLARMLKGSAHAFNLTDNQAANVRMSS
LASSVLCLQEGLEPVMQMTCRDRNRIAMQSDLLGACALGVHNVLCISGDHQVFGNHPQAK
NVYDVDPIQQLMIFRRMRDEGMNWGGEPLPQPPQPFLGAAANPFADPFEFRVARLAKKVS
AGAQFVQTQCVLDVERFQRFMGYVRERGLDEEVHVIAGVIPLRSHKAALFMKNKVAGMCV
PDHIVDRLRRASDPKEEGIKLCLETIDSLKSIPGVHGVHITAIAWEEIVPRLVQEAGIRP
>A0A5N9DT81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MSKLSTKLKSGKFAVTCELNPPKGTDLEKLFKKADMLKDRVVAINITDSAGSNMTMAPIA
VSHFLNHRGIEPILQITGRDRNRIAIQADLIAASALGITNILTMSGDPPQHGDHPEAKPV
FDLNSTQVLDAMKSMQGGKDLGENVLEGNPEFFRGAVVNPGAKDLESEFAKMEEKVSSGA
QFFQTQAIFEPDALEEFMVTAKKFDVPILAGIIVLKSTKMANYLNSYLPGISIPDNIIKS
LDLNDREAIKKESVSITSNIIKEIQGMCDGVHVMAIGWENTIPDILDQSNIRN
>A0A0P7WVY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. HL-58|TrEMBL
MKLVREKQAYSPHDKETAAKLHALVRSASLEATPRQVMTTDDLPDLLPGGTCVYVPFLPK
GQFSETLEACRRLLEIGMQPVPHVPARMAESRGQLRDWLSQLDDSGVDRLLLIAGDSDAV
AGPFPDTLAVLESGLLAQFRFHGIGVAAHPDGHPMADRATLHQALGIKREYARTTSTRLW
VVTQFTFDANVVTDWLQSLGDVLEEVPVYIGMAGPTRVKTLIAYAAQCGVGASARLMLRR
PGSARMLRAWTPEGMLQALVRYCLDNPETLLRGIHLFPFGGLRKSAQWIQEHSGSIEDQK
GQCHESSL
>A0A3D4XHN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rikenellaceae bacterium|TrEMBL
MTVLEKIQTAKKPLFTFELLPPLKGHSIDKVYASIEGLLEFNPAYINFTSHRNETLIRER
PDGSLERRVARIRPGTIALAAAVKYKYDITVVPHVLCGGFTREETENALIEMNFLGIHDV
LALRGDPVRGSRSFIPEKDGHENADGLVRQIVNLNSGRYLDETMEHAVPTSFCIGVAGYP
EKHFESPNMEADIAWLKAKVDAGAHYIVTQMFFDNAKFFRFVEACRAAGISVPIIAGLKP
ISALNDIRLLPQTFHIDVPNDLYKAVAACKDDVAVREVGVEWATMQSRELLKAGVPGIHY
YTLGRSDNVAKIVRGSF
>A0A5N9AK22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MKYLYQIVVDTPRARQYNRHTFCGKIVIGDKLSRFSDLLERGEFVITTDITSSTGVDTSG
ISSQLASVEHLVDAVILGFRNDYNHATPNPIGLIPTILGHGLDAILNVECRDRNRLALQS
DLFAASILGIENIMCVTGDMFIGNEYGDIETVFDVGSADLIHIASNLSNGIDVIGSHIDN
PPKFYVGGMVNPFASELADEIIRMKDKVEAGAKVFITQPFFDIDRLEEFRAAIGSIQAKV
IASILVLDSVDRAKRMNNMPGIEIPQNIIMEIESSAEHKSKGIDIAARTINKAKAIYDGV
HIINLGLIDVVRLVLEKSGIKRSSLQ
>A0A641AE34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MKSVLEALEKREQKPFVACDFSPPKAGTEDLLTNIAELTPDMFLVAYAPGKSVRINSIFV
ADWIQTQVNIPSIFTISPRDMNKNAIQSLLLGAQLRELDNVFIVKGDKFSIQDLVLQNAV
DDFKPTELVASIRSMNERRDFLGKELYYPTTFCIGAALDISRSWKNEAWLTKLKIEQGCD
FLISQPVFEPELPDRFLEFYRGEIGENLNVPILWGIQMVDKNTVSFATVPEWVHRKLEDG
YLPYEIAINLIGRYLEKGLDTFYLIPTIFKGGRRDYLSAQAVIEEIK
>A0A0A1ULN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani AG-3 Rhs1AP|TrEMBL
MKVTEKIQQAEKDGRIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSELVKTCQGAIGIETCMHLTCTNMHQEKVDIALREAKANGCRNILALRGDPPSGQEE
WTSVEGGFQHGIDLVRYIRREYGNYFDIAVAGFPQTIQLPEAEAKQEMQWLKEKCDAGAN
FIFTQMFYDADVFIRWVKAAREAGITIPIVPGINPIQTWNGFIRATSLSGTEIPQDLMDT
LEPHKNNDEKVRELGIKIVANLCRRILDAGIGIKGLHFYTMNLEKGTKMLLEELNLVPRV
ETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQTPEEGRKIWGTPTTIDDVKDLFAKFCSKEIKALPWSDQPPSTEMLVIGQQLT
RMNELGYLTINSQPAVNGVRSDDKAFGWGPKNGYVYQKAYLEFFVHPDQLQTLMKRIERD
TNVTYYAINKQGDLKTNSTSDGPTAVTWGVFPGKEVVQPTIVEAVSFMAWKDEAFELGCQ
WAKIYEPGSPSRKLIEDMMDEYFLVNLVHNDFHDREAIFRPFFADAGLKTNGCTEAPATN
GIKQVNGLTNGHAMTVHA
>A0A3C2CBR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFKPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEPSVGGHKYASDLVKQIHDLGIGEYLHGKIESDTPMQKLLSVSDS
ILP
>A0A519LKX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MEFLEKISIRKRPGTVGICSAITNKYQIDTVPHIICGGFTVEETENALIDLSFLGIDNLL
VIRGDAIKTESSFTPEQKGHTYALDLLKQVNDMNNGKYLYDEVEDVQPTDFCVGVAGYPE
KHFEAANLQSDLMYLKEKVDAGAKYIVTQMFFDNQKFYDFVKACREVGINVPIIPGLKPI
TTKQQLVNLPKIFHIDIPEDLACEIRKCEKDSQVRQIGVEWAIQQSKDLIKFGVPCLHYY
TMS
>A0A2Z3YMY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium provencense|TrEMBL
MHSDPSPESPTGQAPEPVPAPGLPGAPGVPGGHSLQVAVSDTLKRGTPGRVPFSVEFMPP
RDDAAEARLWSAAEAFHDLGASFVSVTYGAGGSSRQRTERVAGKLARKPLTTLLHMTLVG
HTGEEIRAILREFASLGLTNLLALRGDPPGDPLGEWQGIEGGLVHAIDLIRLIRSLPECA
DFDIGIASFPEGHYRAASLEDDTRHTVEKLRAGASYSITQMFFNVEHYLRLRDRLAAFDP
VDGAKPVIPGLMPITSLRSVRRQVELSGCELPREMEDLFTRVAAGDERKNAAAIRKVGIE
VTTRMAERLIAEGAPDLHFMTMNNVRATQEVLHNLGMAPAYGPGLGQDAVR
>A0A1L7FDW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoalloteichus sp. GBA129-24|TrEMBL
MFSVEFFPPRDDESERRLWRAVRELEPLDPAFVSITYGAGGSSRDRTIRTTGRIAQETTL
VPMAHLTGVNHSLAELRNVIGWYAAVGVHNVLAVRGDPPGDPLGEWVPHPEGITYAEELV
RLVRELGPFCVGVAAFPYGHPRSADLEVDADHLVRKIRAGADFAIAQLFFQPDDFLRLRD
RLAARGCDVPLLPGVMPLTTQRMLTKTVELSGADVPVALARRLERHADDPAAFRAEGIEI
VTELCSNLLAEGVDALHFYTLNRATATREVVARLGLLPVRP
>A0A3D0FRW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rikenellaceae bacterium|TrEMBL
MKVTEHIEKSKGRTLFSVEILPPLKGQNIESTFKSLDSLMEFEIPFIDVTYHREEFEFKE
FPDGHLERRIVKKRPGTVGICAAIQNRYKVDAIPHVLCGGFTREETENFLIDISFLGIDN
VMALRGDAIKSESCFVPEKGGNQHASELVKQISDMNRGIYLDNELLDTSPTNFCIGVAGY
PEKHIEAPSMESDIHFLKEKVRNGANYIITQMFFDNRKYFDFVERCRIEGISVPIIPGIK
PIATKRQLNLLPLKFKVDLPDELVKMIVKAKDEEEVRQIGVEWSIGQCRELIKAKVPLIH
FYATGRAENIVQVCRSLRV
>A0A5N9HJN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MGFIQEIEETEEKFGNVFITDISPPKGINKISYEPIININSDFLLIIDSPGGSVRSAPIP
FAYKLSVEENQNVIFTMNCRDMNKLAIQSNLLGAQMLDLHNVFIVNGDDSTKHKQSVKPV
NDYTATSLISDIVNLNLGIDFQ
>V7IBA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eikenella corrodens CC92I|TrEMBL
MLHNTLSFEFFPTRTPEGREKQKITRKQLSQYQPEFFSCTSGAGGTTREGTMQTIRDILA
EGMAAAPHIPCVGLDAGELTDLLQEYKDLGIRHVVALRGDIPSGMGLGTTGLHHANELVE
LIRHRFGDWFHIEVAAYPEYHPQSRSAEDDIQSFVRKVKAGADSAITQFFFNADAYFRFL
DDVRGRGVEIPIVPGIMPIANFSKLARFADICGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCGRLLRHGAPGLHFYTLNQAGLSSTICQRLGY
>A0A0E1CLK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae 30660/NJST258_1|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A199AYV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia sp. 111N12-1|TrEMBL
MTQLPDSDPTDGGRHPSIVERIATSTTPRVPFSVEFYPPRDEAAEDRLWRAATVFSDLGA
AFVSVTYGAGGSTRDRTVRVVERLVRETDLLPIAHLTAVDHTVAELTDMIRMYGEVGVSN
ILALRGDPPGDPLGEWTAHPEGLHYAEELVRLIHEVGDFHVGVASFPEGHYRARDLEHDS
EILVNKLRAGAEYSITQMFWDVEHYLRLRDRAVAADPEQGAKPIIPGLMPVTSLRQVQRM
VELSGCALPDDLAERLRTAAGDGPEENRAAVREVGIDLTTRMCERLIAEGVPCLHFNTLN
FSKATHEVLTNLSMAPAPGVAAGRI
>A0A6M0EZG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symploca sp. SIO2B6|TrEMBL
MSNAIQNSKSQIATETVSLSNYLQDTTPTKNSFRHAAESGKFLITAEVTPPKGGNPAQMV
KMAKTLKGRVHAVNITDGSRAVLRMSSLAASVILLQQGLEPICQLACRDRNRIALQADLM
GANALGICNILALTGDPVKAGDHPEAKSVFDLESVRLLQLISKLNQGVDAHDKPLTDDVT
DLFAGAAVDPQLKSWSGLQRRFERKIEAGAQFFQSQLITDFERLEKFMDEIAAGSNKPIL
AGIFLLKSAKNARFINKYVPGVNIPEAIIERLAAAKEPLLEGMNIAAEQVQIAQQICQGV
HMMAVKREDLIPQILDLAGVEALHN
>U1N3F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloquadratum walsbyi J07HQW1|TrEMBL
MALGAQSAVDQDGVSNLLRGARFELMPFDSFNDELESLPAGSSIAITTSPQLGIEQTVER
AEEAAAQGYEVVPHIAARYVEDEAQLASIAERLSDAGVTDLFIPGGDREEPAGEFTSAYD
LLEVLDELPYSFEDIGITGYPEGHDFIDEDELITVMDRKAPYATYIVTQLCYDPETILEW
VESVRERGVDLPIEVGIPGVMNYQKLLQISQKVGVGDSIKFLRKTTGIFEFVRQLIGSRG
VYEPDELIDGLSPYVEDEYYNIRGIHIYTFNQTPDLESWRQTRLA
>A0A7K2EXP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4921|TrEMBL
MALGTPSTRTDHARTVRELLATGETSFSFEFWAPKTEKGERNLWNALRRVEAVGPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVRYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDSDIGHFVD
KCRAGADYAITQMFFHPESYLQMRDRVVAAGCDTPVIPEVMPLTSVKQLERFAQLSNASL
PSSLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A2Y9K969|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enhydra lutris kenyoni|TrEMBL
MVNEPRGDGGPPPRSEGSSSGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSQGQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRH
IRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSRLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFAHYLSGEPNQHGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWVEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPEPEQDTQAL
>A0A5F2ICC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1D.F.Ca.ET.183.01.1.1|TrEMBL
MSARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPEAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRRPWKREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A0U3QQN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter alpinus|TrEMBL
MPSRVEIIPTAGIVESVVAQLPAGTTVTVTCLPNHGIERTVAASLELAGLGYNVVPHLAA
RSIGSREQLASILRDCRAAGIAEVFAIGGDKAQAAGPFDSSDVLVRDVAELGSGNFRIGV
AGYPEGHPNISDQQLLDSLRAKADVADRIVTQMCFSAELIGTYAAMLRSEGITIPVWAGV
AGLVPRTKLISLATKIGVGSSLRFISGKGALGMRLMGGTRYNPDGLVAELTALPTPPAGI
HLYSFNNVGSHAPVPA
>H9UDX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium pennivorans (strain DSM 9078 / Ven5)|TrEMBL
MKVTEMVKERRIISIEIIPPKRGEDVENIYRTLDKLMNYDISFISITRHPVEVDYIEYED
KIVKVHKVKRPGTLGLTAALMNRYRIDVVPHLICVGMSKFEMEDMLIDLDIMGVDNVFVI
RGETASSVENYNKGDYKYAVELVRQIKDLNMGKYLYTSAKPTNFCVGVAGYPEKHYESPN
LETDLKFLKQKVDAGAGYIITQMVFDAQVYKDFVERCRSIGINVPIIPGVKPVVSKSSVF
NIPKKFFVTIPQRFVEAIDNAKTKEEEFKVGIRFTVELVEKLIEYSAPGIHIFTMGRGEE
SCEVIKHTQSILK
>A0A4Q5YVD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriaceae bacterium|TrEMBL
MPGSAVAAARPRPVRPGRAPSVADLLAAGERPLVSFELFPARDAEQHRQLWTTIRELESL
GPDFVSVTYGASGSTRDRTVSATQQIAEQTTLRPVAHLTAASQSRDELRHVVGAYASVGI
NHV
>A0A258Z7U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium 24-56-14|TrEMBL
MILPFDQMQEASRALAAPLFAGLAGDCEISFEFFPPKTEKMEEQLWDSVVTLAPLAPRFV
SVTYGAGGTTRERTHNTVARIARETNIPAAAHLTCVEASKGEIADVAHAYWEAGVRHIVA
LRGDPPSSDGKFVPHPDGYASAADLVEGLRKLHPFEISVSAYPETHPEALSAASDIDFLK
RKLDSGASRAITQFFFEPETFFRFRDAVAAAGVDAEIVPGIMPVSNFAAITRMSAMTGTA
IPVWMEHLFEELDDHPPARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GKRPAGAAQEQAA
>A0A5N7SAI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MPAPGSLRTEAFINTFSLEVSAKAMPALRAEAARIPHGTTISIPYLASEDDDARLAAARM
VRALGFEPMLHLSARRIGSRAALERFLERAASEAGVEQCLVIAGDLATPAGPFADSASII
ETGLLERFGVRVVGIGGHPEGHPVMSSDDRWQALERKCRAIESRGMAPLIITQFAFDADI
VLAWLNVLRARGINVPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGVSIGRLLGTA
GPEVFVDRLVQGLTDAHGMISPHLFPFGGIAPSLDWIERYRRRGPFPRVRR
>A0A355YCB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MTALSFEFYPPKTDDQRAQLDRTASRLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLQAAPHLSCVGGTREEIRELLKLYRAIGVRRIVALRGDLPSGMGFPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLRHFKAKVDAGADAAITQYFYNADAYFHFVDA
TRGLGVDVPIIPGVMPISNFSQLRRFSEQCGAEIPRWIARRMQAYGDDTESVRAFGADVV
AALCERLIAGGAPSL
>A0A3Q8Z507|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A0U3P8S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter alpinus|TrEMBL
MSPPSLNRASAPLTHSAPIALSYELFPPKNQAAEAALWNTIRELESTNPDYVSVTYGANG
SNRDTAVELLNRLLTETSLLPLAHLTCVGNTADELAEIISELLDHGVRGILALRGDLPKD
APAQPRPGSLYYAADLIELIRRVEQRRSALLCAGKVAIGVAAYPAQHPESPSVEHDVEVL
LAKQNAGADFAITQVFFHADQYKDLVVRARRAGVSIPIIPGVMPLTSLRRVKRLGDITGV
APSTSLLDALGRAEDAAESRRIGVAATVDLARAALDAGAPGIHLYTFNEHAAALEVLDKL
QLLRPGRPPVAPRAAPTDSARLVRA
>A0A545SMP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliiroseovarius halocynthiae|TrEMBL
MITPNISFEFFPPQSLDASFRLWETVRQLAPLNPNFVSVTYGAGGTTRELTHDAVGTIHK
HYGLNVAAHLTCVEASRDETLAIAKSYADVGVKEIVALRGDAPKGADRFTAREDGFADSV
ELIEALAGTGDFHIRVGAYPDPHPEAADLDADVAWLKRKVDAGANSAITQFFFEADTFFR
FRDRCEKAGIDVPIIPGILPIENWKGVRKFAERCGATVPAWLDDAFRKAERDDRTDLLAT
AICTELCSDLIDGGVEDLHFYTLNKPGLTRDVAHALGVTPQINLANVA
>A0A845UNT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus ferrianus|TrEMBL
MAHSVEFFPPKNAAGEERLRDAVTTLLPLNPEYASVTFGAGGSTRERTFAAVTMIRQEYG
LESVPHLSCIGSTVAGIREILEDYRAQGIHRIVALRGDLPEGMENPGHFQHAADLVAFIR
RFGGFEIYVAGYPDIHPQAGSARDDVAHLVAKIKAGADAVITQYFFNPDAYLQLRDDLLR
QGVEVPVVVGVMPIGNYAQIARFSAMCGADLPQYVRRRMEAYADDAQSQYEFGIDLLSRQ
CQLLLREGAPGLHFYTLNQAEATAAIWRNLGLES
>A0A7C8NT92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orbilia oligospora|TrEMBL
MHIKDKIAACEKAGKPCFSFEYYVPKTAQGVQNLYDRMERMGSFGPQFIDITWNAGGRLS
NLTTEMVNVAQTVYGLETCMHLTCTGMEKEKVDNALQEAYNGGCTNILALRGDPPRENEK
WSAVPGGFRYAKDLVKHIREKYGDYFDIGVAGYPEGCDDEVDPDILLDHLKEKIDAGGTF
IITQMFYDVDIFLDWVNKVRAKGITVPIIPGIMPIHTYAAFIRRATWTKIHVPEKWLEVL
EPVKNDDVAVRDIGRDLVVELCKKILAAGINQLHLYGTTRSTHYTMNLATATRMVLEGLD
LMPSLEARELPALPFKSSLGLGRREENVRPIFWKNRHKSYVARTQEWDEFPNGRWGDSRS
PAFGELDTYGIALKGTTEQNIKLWGRPETVAEIADLFVRYIDGKLETIPWSDSPIDASAE
PIKAQLSELNKRGFLTTNSQCALNAVKSSHPIHGWGPKNGYVYQKMYVELLVSPDVLSEL
ITRIERSPDLTYYAVNKAGVLHHNAPAGGSPNAVTWGVFPGKEIVQPTIVELISFLAWKD
ELYRLGEDWAACYPQSSASRHIISSVMENWFLVNIVNNNFLDNDSIFELFKDLKIDNLNE
KIPVDEYLQNLKITDGSNGTAHEATNGAPAA
>A0A1L5BJZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium indicum (strain DSM 16412 / CCM 7286 / MTCC 6364 / B90A)|TrEMBL
MTLGFPSVEAAQAWQAPLYADLAGDVNVSFEFFPPKSEKMEEQLWSAIQTLTPLGPKFVS
VTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASRAEIDEVADAYWEAGVRHIVAL
RGDPPEMGAKFEPHPEGYKGAAELVEGLRKRHLFEISVAAYPETHPDAQSAQSDIDNLKR
KLDAGATRAITQFFFEPDTFFRFRDAVAAAGIDADIIPGIMPVSNFAAVQRMSAMCNTDV
PGWMGKLFEGLDDHAAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVATNAV
>A0A7X4ITW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boseongicola sp. SB0675_bin_26|TrEMBL
PIEDWTRTKRFARRCDVQVPTWLADAFETALRDDRHDLLAISVCTELCSDLLEGGVESLH
FYTLNKPHLTREVVRALRSAPTASLRYVA
>A0A1F8U9X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium RIFOXYA1_FULL_46_5|TrEMBL
MSFVSAQYLESINRNLQDVAGKVNVSFEFFPPKTEQMENTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASRAELERIAKDYWDNGIRHIVALRGD
LPPGNKEKPALYAADLVEILRSVADFDISVAAYPEVHPESPNAQFDLLNLKRKVDAGASR
AITQFFFEPEKYLRYRDRCAAIGIDVEIVPGILPVTNFQQLQKFATMTNVAIPGWMNKAY
EGLDQDATTRNLVAANIAMDMVKVLSREGVNHFHFYTLNRCELSYAICHLLGVRPQSVIA
>R7YMH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coniosporium apollinis (strain CBS 100218)|TrEMBL
MEKITDKIAALPQDANYFSLEFFPPKTQMGSSNLQARLERMSRALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRSLVDEALEQAKALGVRNILALRGDPPRSDE
YRDEGAPVSGDSNDDFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHSDQSHPEHQDPKFDI
PYLVEKVQAGTDFIMTQLFFDVKAYSDFEAMLRSHPSGAFKSIPVIPGLMPIQSYQILRR
ITKLSHARLPPEILSRLDAVKGDDEAVKRVGVDILGEIVQEIKRTTPQGPRGFHFYTLNL
EKAVAHIVERTQLIPPISQDEDDGDDGDDAVAIDGDDDILPPLGAINKAARRRLSSVNSA
PHNRVIVERPSTSSNASYEAPDDEVGVPRDKINTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAFGEIDGYGVSLHVSIPQAVKLWGYPTEISDLTTIFRRHISGELEAVPWSEE
GLNPETKTIQEELLKLNSKGWWTVASQPAVNGVKSTDPIFGWGPKNGFVFQKPFVEFFLP
SADWQKLQRKLSEHEEVTYFAGNKAGDIAATKEDSVHAVTWGAFAGKEIISPTIIEAVSF
RAWLEEAFSIWSEWQRIYPPQSPTAKLLGSVRDDYWLVNVIHHGYPEKDALWRLLLEE
>A0A5C3EMC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ustilago trichophora|TrEMBL
MANGIDATTLPPKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMAD
LGPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFG
CRNILALRGDPPAGQSEWEPHAAGFTRAKELVEYIREQYGDYFAIAVAGFPEGHPEAIDG
PDKELERLKEKIDAGADFIFTQMFYDFDIFAKWVKDVRAAGITCPIIPGVMPIQTYGGFQ
RATARFGTLVPQYFHDALDPVKDDDMKVREIGTRLVGDMCKKIVGTGLGISGLHIYTMNL
EKGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRRDEKIRPIFWANRAKSYVNRTETWDEF
PNGRWGDARSPAYGDVDAYGVKLRYSNEEAKEMWGTPTSLEDVKALFQKFCAGQVKALPW
SETPVARETSVISEKLTKMNQLGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEF
FVSPEDLDALIARIEADPQITYHAVNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVE
SISFLAWKDEAYEIGRNWAKVYEPTSPSRKFLEDLFNKYFLVNVVHNDFKAADSIFEPFL
STSTASSSVNSSLSGIGSSVADAAGRVANSISSLANGVSNEHTSAPAPAA
>D3Q9W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)|TrEMBL
MPGQPAAIVDLLREGPTFSFEFFPPKTPKGEETLWQAIRELEPLQPSFVSVTYGAGGSTR
AGTVNTTDRIAAETTLLPLAHFTAVNHSVEELRNLIGHFAAGGVRNIIALRGDPPGDPLG
EWTQHPQGLKYAYQLVELIKSSGDFCVGVAAFPEKHPRSPDWDTCTQHFIEKCRAGADYA
ITQFFFDWQDWVRLRDAVDAAGVDVPIIPGVMPVTNVKQIKRMAELSGAEFPADLARRLQ
AVAEDADAVRAIGVEVATELSQRLLAEGAPGIHFITMNRSTATREVWQNLRPVAARSA
>A0A1M4WHE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter uzonensis DSM 18761|TrEMBL
MLKNENLCTKLKKRKFVVTAEISTPKGVDITKTIEEARKLKGIVDALNITDSPMANMRMS
PIAVAHLLQDHLNIETIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDDPSHGDTPQ
AKGVYDVDSIGLLKIISAFNRGYDYNGNKLDSPTEFCAGTTANPSDLREEAIEKLKVKIE
AGAEFIQTQPVYDEDILFKFIEKIKNFNVPLLVGILPLKSYKMAVNLNEKVPGIDIPEKV
LERLKDGGKEEGINIAVEFIKRIRSEVGGIHIMPLGSTDAVLEIISRVDDLACDFKENKV
QMN
>A0A1I3ITB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Celeribacter neptunius|TrEMBL
MTTAPKISFEFFPPKNIEACFSLFETLQVLGDMAPEFASVTYGAGGTTRELTHDAVALLH
RKYGWNVAAHLTCVNATREETLAIAQSYKEVGVNEIVALRGDPPKGAGTFTPAEGGFANS
VELIEALKATGDFKIRVGAYPDPHPEAQDGHSDITWLKRKFEAGADSAITQFFFDPESFF
RFRDRCEKEGITGTIIPGILPITSWKGVQKFASACGTPVPARYGEEFDASDDHAALAVDL
CTGLCESLIENGVEDLHFYTLNRPTLTKAVCSNLGAA
>A0A380MWL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Suttonella ornithocola|TrEMBL
MNENKLPVRVSCEFFPTATEIGGEKLAQVRDELSVFQCEYYSVTYGAGGSTQARTMQLVK
RICEENERPVMPHLTCVSATQAMLEELLDDYYALGIRHLMALRGDMPAGSYYMGELADAA
DLVRLVRSRWGEQATIVVAAYPEKHPRAKTPYQDLQQFKRKCDAGANEAVTQYFFNADAY
FRFRDEVAAIGVTLPIVPGIMPITNYAQLARFSDACGAEIPRWIRKRLEAYQNDVQSLCD
FGEEVVAVLCQRLIEQEAPGLHFYSMNRSDAMLGIGRRLGWIK
>A0A1G9WXG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetanaerobacterium elongatum|TrEMBL
MKLCKLFDEKKVVFSFEIFPPKKTSSIETVYNTLDALKGLHPDYISVTYGAGGAGSGKTC
EIATLIKGKYHIEPLAHLTCINATREQILAELEAFKKSGIENILALRGDRNPEIPACYDF
AYAGELVEFIAQHGDYNIVGACYPEGHPECNSLEEDITHLKDKVDKGVSHLNSQLFFDNN
DFYRFLELTQKAGIFVPIQAGIMPVTNSRQIERMVSLTGAKLPSKFSKIMARYGDNPEAL
RDAGIAYATEQIVDLIASGVRGIHLYTMNLPYVAQRISTNISSILQTSNQ
>A0A101NHW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cellostaticus|TrEMBL
MTTFSFEFFPPKTATGEQALWQAVRRIEPLAPDFVSVTYGAGGSSRERTIEVTKRIVSET
TLRPVAHLTAVGHSVAELRRIIGQYADAGVRDVLVLRGDPPGDPKGPWEPHPDGFTHAYQ
LVELVRSLGEFTIGVAAFPEQHPRSPDWDSDIRHFVAKCRAGADYAITQMFFDVEDYVRL
RDRVAAAGCTTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAARERPDDAYRIGV
DHATAMADRLLAEGAPGLHYITLNKSTAALDIHRNVLNSTRSLHAR
>N4UDI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. cubense (strain race 1)|TrEMBL
MDRMYNLGPKFIDITWGAGGRIAELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALL
KAYKAGCTNILALRGDPPRAQDKWTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGS
DDNKNEDELLDHLKEKVDMGASFIVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIAT
YASFLRRANHMQAKIPQEWLDALEPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYT
MNLAQATRMLLEELQWAPCAERPLQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQ
DWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEI
ESLPWSEAPLTTEADEIREELIELNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQK
SYLELLVHPDVFDKMITRIENHPDLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQ
PTIVESISFLAWKDEAFRLGVDWAHCYDMSSPSRALLEGVMNDWYLVNIGE
>A1ZRW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microscilla marina ATCC 23134|TrEMBL
MTKIIEYIQNSEKPLFSFEIIPPLKGQSIQSLFNSIEPLMEFKPKFIDVTYHREEYVYRN
RGEGLLEKHVTRKRPGTVGICAAIMHRFQVDAVPHLICGGFSKEETENALIDLNFLGIDN
VLVLRGDAIKSEGRFTPDPNGHQYASELLEQVVNMNNGVYIDDEIKNPFPSSFCIGVAGY
PEKHFEAPNFTTDLNYLKMKVEMGAEYIVTQMFFDNQKYFDFVKQCRKEGINVPIIPGLK
PLTSKKQLTVLPSIFHIDLPQELVDEVSKCQNNEQVRQVGIEWGIKQSKELIKFGVPVLH
YYSMSKSKAVKEIASALF
>A0A2W7KWT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 2848|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALLAEYQAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGNHFHLEVAAYPEMHPQARNFESDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7W6BHP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium jiangsuense|TrEMBL
MGKAVARLLDDYSLEATAKDIDALEQAAPALRPGTLVSVPWLPAETMAARCAAAVAIRRL
GFTPVPHIAARRVKSRQALQDFLARCTGEARVDHLLVIAGDSAEPEGPYRDALAVIESGL
LADHGIAAVTVSGHPEGHPAIGREALMRALQDKSAALGAQGMDCRIATQFAFDADAILRW
LAEIRAAGIGHPVRIGVPGPASIKALLRFAALCGVEASTKVLAKYGLSLTRLIGTAGPDR
LVDALEARLDGDVHGLVQAHFYPFGGIGRTVQWAVQWAAARQSAAETAA
>A0A7I7Q787|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium stomatepiae|TrEMBL
MISAEAVPRLLKDFSLEMTGKDVAELAEARPVIPAGTKVNITYLGTEGFDVRLRAAAAVK
EAGFQPIPHIAARRLTSRSELERYLAALQRLNASAHVFVVGGDPATPEGPYDSALALIES
GLLGRAGVRSVGISGYPDGHPGIPAARLWTALDDKAAALAAQGLAGSITTQFGFDVDRVV
AWLTQLRQRGINLPVRIGVPGPAGIRRLLSYATRFGVSASAGIARKFGFSLTNLLGTVGP
EAFVTELAQRSTTADLGEVLVHFYTFGGLRATAGWVHEHGATR
>A0A3M8TL69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces botrytidirepellens|TrEMBL
MALGTASTRTDRALTVRDLLASGEQSYSFEFFAPKTDKGQHTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRATEQIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVRHPDGITYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADFAITQMFFYPEDYLRLRDRVAASGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDAAAVRSIGIDYATELCARLMAEEIPGLHFITLNHSTATLEIYKNLG
LHQRS
>A0A7S3VSD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dunaliella tertiolecta|TrEMBL
MTCKKMEPHTYMVHRHEQTFQTFTISPALPQALVIRHLADACLAFFLENCLCGTLSLMLM
SMLKQTHADAAGKTEQPGTAYTRSGRAADALLLVSGSHPVRTLPGSKLLLPSSLNTLEAA
NHLKRVGAIAPSTQLWAVANPNVEKDASLAEQKVARGATLFLTQPPFDMDSFAAWVEDAR
ARGVWDSARLVVGHPMISSAGNLAFWMSLSSCLGRPACQQLLRQVSTAEASNKQQAEQLC
AQYNEHLVSQVIDT
>A0A7Y2X770|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansiaceae bacterium|TrEMBL
MHIRDIIKPHEPTFSFEFFPPKSSEAADTLFETIKQLSSRHPSFVSVTYGAGGSTRELTH
DLVVRIKETTSTPPIPHLTCVDHTAEEITTTLERYASVGIGNILALRGDPPSDNGNYNRS
NDAFPYAADLVRHIRQFNESGKHPDPRGFGIGVAAFPEGHPGTPNRLLEMDHLKAKVDEG
ADFICTQLFFDNHDFFDFRDRCRLAGISLPIIAGIMPITSAKGIKRMAELAAGAHFPAKL
LRALKRAGDNQEAVQRVGIHHAAEQCAGLLNADVDGIHLYTLNQSRATQEVYASLGMG
>A0A1I4FEE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. 5mfcol3.1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1F8MJB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_51_18|TrEMBL
MVSRFKEALNSGKFVITSEIAPPKGTNLEKMLHHIDILKDRVDAINVTDHQSSVMRFPSL
GGCLAIKEKGGEAIMQMTCRDRNRMALEADLLFAYCRGIRNVLCLTGDAVPVGDHKEAKG
VFDLDSLQLLVAIRQMMEGQDLGGNKLEGEFEFCAGAIVTPEAKPIEPQLIKFEKKIEAG
AEFFQTQAIYDLDNFKTFMKHARQFKTKILAGIVLLSSARMAKYMTENVPGIFVPQRLID
EMSAVPKEKMLEKG
>G9ZI96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cardiobacterium valvarum F0432|TrEMBL
MNNDKTDLQQLIHQYSIEIVPKTLRQIGDIRPWLAPGTEVYVPNLRSHKISDTIDACALL
QSQHMQAVPHLALRNIASEDELRHTLDRITALGIRRILVLAGGAKEPLGPYGSVKDLMKT
GILQTYPFEHIGFAGHPEGSPDIPKAEQEAAEAQKQGYALTYPHDYYLTTQFCFQLAPIT
AWLDRLRARDITLPVHLGIPGVASTTSLIRHAQACGIGQSINFLWRNGRNIRRLMGLSTP
DKLLTDLAAYRKTRPENAIRKLHFYPLGGFETTINWLRAIEAGNITLTDEGFTANI
>H6MSP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia polyisoprenivorans (strain DSM 44266 / VH2)|TrEMBL
MTSSPPALSVVERLAAPPANGVVHFSVEFMPPRDIEGEARLWRAVRVFERLDPAFVSLTY
GAGGSTRDRTVRIAGELATQTTLLTVAHLTAVNHSIAELRALVGSYADQGITNLLALRGD
PPGDPLGEWIRHPQGVQYARELVELISGLGDFHVGVASFPEGHHRARDLDQDTDVLVGKL
RAGAEYSVTQMFFDVEDFLRLRDRVARADPEQAAKPLIPGLMPITSLASARRMTQLSGSV
IPPAVEQRFAEAAGDGPEEDRAAVRAVGIDFATETAQRLIAEGVAGLHFCSLNFAKATCE
VLDRLGVGVPDALPTVGAR
>A0A235GBB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. OK302|TrEMBL
MTFDAVRGRSSEGWASRTPSIVDRITSHTGGRIPFSVEFSPPRDAEAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSIDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPDGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
HDTKYLVAKLRAGAEYSITQMFFDVDDYLRLRDRVSAFDPEQGAKPIIPEIMPVTSLGSV
RRMLELSGSSLPPALERRFDAAAGSGAQENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTSEASTGSAAAR
>R6FUY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:192|TrEMBL
MNIADIFKKKTVFSFEVFPPKKESGVETVYNTLRELKDLNPDFISVTYGAGGSGIAKATT
VDLCAKIKNELNTETIAHLSCLYNSKADIDRILNDLNEKGVKNILALRGDANPDYEVKHD
FKYASDLTEYIMSKNMGFHVSGACYPETHQEAANIVEDIKNLKIKVEAGADHLISQLFFD
NNVFYDFIEKVRVAGIDVPVEAGIMPVTNKKQIERMVSMCGASIPAKLSKVLQRFGDNPV
AMRDAGISYAIDQIVDLVANGVDGVHIYTMNDPYVAKRISDSVTNLVKNK
>A0A1Z4RSR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chondrocystis sp. NIES-4102|TrEMBL
MISNLQQAVMQQKFIITAEVAPPKGGNPSKMLDVAAKLKDRVHAVNVTDGSRAVLRMSAV
GASVILLQHGIEPVCQIACRDRNSLGLQGDLMGAYALGIRNILALTGDPIKAGDHQNARG
VFELESVRLLRLINKLNSGLDYNDKQMPDEALNLFPGAAVDPQLKSWSSLQKRFEKKLEA
GAQFFQSQMITDFDRLDKFMSQIACVSDKPVLAGIFLLKSAKNAQFINKYVPGVHIPDEI
IDRLGKAEHPLQEGIKIAAEQVKQAQSLCQGVHLMAVKCEELIPEILDLAQIKPLSCP
>A0A246Q326|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp. HZ28|TrEMBL
MTDTKTPALSLEFFPPRDIAAQERLVRAAKQMLAMHPRYVSVTFGAGGSTREGTADTVRT
MRNLGVDAAPHLSCVGASRDDLRKILGAYREEGVKQVVALRGDLPSGMGGGAGELRYARD
LVAFIREETGDWFHIEVAAYPETHPQAESSAADLDHFVGKVQAGADSAITQYFFNPDAYF
DFIDRAAAKGVTVPIVPGIMPITNHSQLVRFSQMCGAEIPRWIRMRLAEYGDDKASIRAF
GIDVISGLCQRLLDQGAPGLHFYTLNNAEAPMAIWENLGL
>A0A447CGR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Podospora comata|TrEMBL
MHIREMLADAERTGAPSFSFEYFPPKTTQGVQNLYDRMERMNNFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYLGLETCMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPPREKEK
WEAAEGGFRYARDLVQHIRKSYHEHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDAGATF
IVTQMFYDADNFVRWVGKVRARGINVPIIPGIMPIATYASFLRRANHMNCKIPDEWMQRL
EPVKNDDVAVRDIGKTLVAELCRKILAAGIHHLHFYTMNLAQATRMVLEELDWMPSPDRP
VKQALPWKRSLGLGRQVEDVRPIFWRNRNKSYVARTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRQKWGEPTCIRDIANLFVRYLNKEIEYLPWSEAPVAEEADVIKDYLLD
LNKRGLITVNSQPAVNGVKSTHPVHGWGPSKGYVYQKAYLELLVSPEVYPEIKKRIENHP
DLTYHAVTKSGMLETNAPSDAPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGSDW
ARCYEADTPSRLLLEDIMKSWYLVNIVNNDFHQGETLYEVLKDLQEPNLDKVPQSPATNG
EAANGVEAST
>A0A0E3Z2F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas suwonensis|TrEMBL
MTPLSFEFYPPKTDEQRAQLDRAAAKLRPYAPDYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGNREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYAAELVELI
RAEHGDRFRIEVAAYPETHPQAEDALADLRHFKAKVEAGADAAITQYFYNADAYFRFVND
VRRLGVDIPIVPGIMPISNFAQLRRFSEACGAEIPRWIGKRMQAFGDDAAAVREFGADVV
ADLCRQLVAGGAPGLHFYTLNLAKPTEAVLARL
>A0A3L8B7A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ketobacter sp. GenoA1|TrEMBL
MNSQQQHEKRFSFEFFPPKTDVGVEKLNLVQQTLAEKKPRFFSVTYGAGGSTRDRTFETV
NNVKNRTGIDAAPHLSCVGDTKAQLAQLLNQYQDAGINRIVTLRGDLPSGMGASLGELKY
ASDLVAFIREQSGDHFHLEVAAYPEMHPQAKSMDADLQAFKTKVRAGANSAITQYFFNVD
AYKFFVDSCEKMGLDLPIYPGIMPIINFDNLIRFSSMCGAEIPRWIRMRMECFRGDEQSI
KQLGEEIVTSLCEELLAMGAPGLHFYTMNQAEPTIAIWDNLNL
>A0A267TJC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flectobacillus sp. BAB-3569|TrEMBL
MFLDKIKSKESGILLYGITPPKAQVGPEKVIEIAEKTLARLHNLDIDALVVYDVQDESAR
TSEERPFPFISAHDPFEFAKDHLSSLQVPKIIYRPAGKFTKEELNAWLKEVVNHGFSPVF
VGVPSPDFVPVTSLPEAYGVWRQYQDQSVIGAVTIPERHAVLKDEDQRILDKVSSGVSYF
VSQCVFNVDYAKAMLDALVQACQAKNQEIPTIIFTLTACGSLKTLHFMEWLGIHIPEELK
EEFKASENILDRSVEVCITIADELIKYCIQLGVPVGFNIESVAIRKEEIEASIAMVNQIG
EMLKAEGLRK
>A0A7W6T2X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. SBR1B|TrEMBL
MTDLTIPARADGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTPYSSHPDGYQSSPELIAGIKKRHGDIEVSVSAYPEKHPEARDFDDDIDTLKAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARAFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A496NIV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella sp|TrEMBL
MNNSALHNIEQIQNLLDGLKNQLQTPKVFNKPKDKALFSFEFFPTKTDDGQHKLLQTFDT
LNSLNPQYFSVTYGAGGSTRERTLKIVETLSKKSTTPIVPHMSCIGDSKKEIGELLDYYK
SLGVNRVVALRGDLPSGQVGYGELPFALDLVKYIREHSGEHFTIKVAAYPEMHPQAKSFK
DDIKNLAEKYHAGANEAITQFFYNVDSYLFLRDELAKLGIHQENFPIIAGIMPITKASNL
IRFADSAGADIPRYIRKQLADYGDDTKSIRQFGFETVIKLCEKLIAEDVPSLHFYSMNTV
SPNKELVEALGLN
>A0A7R6XR02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 131-2-1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVVREFADMGVTRFVALRGDPAAGVGT
AYKPHPEGYANGAELVGAMKSAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHEAEAA
GSAAA
>A0A6A4SN17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scophthalmus maximus|TrEMBL
MVNQAPRGEGSWSDSSGASNSGGESSKESSRSSTPVLDADRSDRLRDKMRRRMESADRWF
SLEFFPPRTTSGAVNLLSRHVARRITEDRTRVTNPVGADWEEEDGGFNYAIDLVKHIRSE
FDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVITQLFFRSDTFLKFLDDCRA
IGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITNVIEPIKDNDAAIRNYGIHQAVEM
CRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPI
FWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLHMWGEEL
MKEESVFEVFTCYITAQPNCSGQKVMCLPWNDEPLAPETNLMKDELEKVNRRGVLTINSQ
PNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHG
RNLTNALDFQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYEDESPS
RMIIKYIHDNYFLVNLVDNDFPLENCLWQVIEDMFEMLDAPPEPV
>A0A1N7IQ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium appendicis CIP 107643|TrEMBL
MTEGHFSSRLSASAPLDHLDEAPEDGARRAVKRQQRTALSFELIPPRHDADEAKLKDLIT
GLIAYKPDYFAVTSSRRSGWLQGTADFIARLSECTNLPTIAHLACTAGPVDELADWIRTL
IDSGVRGFLALRGDLPEGETSLPEGYLQYATELLTLIREIEDENAFRLAAGKLALSVACY
PSGHAESPTPDLDLDVLLSKQRLGADFAITQLFFEAEDYLRFAEQSRMAGVRIPLIPGIM
PMTSLKRAQRMGVLSGIEVPQRVADKLSAASDPDEEYEVGMQLTAELAGKLLDAGVGGLH
IYTHNNLAVTQDLLSRLGIEPK
>A0A024HQ69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas knackmussii (strain DSM 6978 / LMG 23759 / B13)|TrEMBL
MSQERRFSFEFFPAKTEAGHEKLLATARQLAGYKPDFFSCTYGAGGSTRDRTLQTVLQLD
GEVKVPTAPHLSCVGDSKAELRALLAHYKDAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGDHFHIEVAAYPEVHPQARNFESDLANFVRKVKAGADSAITQYFFNADSYFH
FVERAQKLGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIPSIQAFG
EQVITEMCERLLEGGAPGLHFYTLNQAEPSLALWNNLQLPR
>A0A103EHP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. TSV86|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRTTCAQLAPLAPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFVRKVKAGANAAITQYFYNADAYFRFVD
DAAKLGADVPIVPGIMPITNFSQLVRFSEMCGAEVPRWIARRLESFGDDKESIRAFGTDV
VAGLCRRLVDAGVPGLHFYTLNGAAATKAVCERLGF
>A0A372NME6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp. WSJ-2|TrEMBL
MTQATAIPARKDIRLSFEFFPPKSAEAEEQLWETAAALSAYDPGFMSVTYGAGGSTKVPT
LATVRQLIKMGLPAASHLTCVGATKEEVNAVVADFQAVGVKHFVALRGDPPGGVGTPYQP
HPGGYANAAELTAGLRGLADFEISVSAYPERHPQSPDVAADVDMLKRKVDAGATRALTQF
FFENDDFERYLERVRKAGITIPVVPGILPVHNLGQVQKFAGLCGASVPTWLADRLGPYDD
RPQERAAVAVELAIRQVQDLIARGISEFHFYTMNRAAMVSAVCDGVGFARNDQQPVTGAA
A
>R6U1N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:964|TrEMBL
MKTNELFKKKTVLSFEVFPPKKSSPINTIYDTLEGLKDTSPDFISVTYGAGGSKNRNATF
EIASEIKNKYHIESVAHLPGIGLTRDDVLEKLGELQDKGIENVLALRGDIPQDYDGSGDF
KYACDLISFIKEHSNVNIIAACYPEGHIECESKIKDIHHLKTKVDAGASQLMTQLFFDND
YFYSFRDRCSLAGIDVPIEAGIMPVVNKKQIERMATLCGATVPKKFRAIMDKYSDNPVAM
RDAGIAYAIDQIVDLIARGADGIHLYTMNNPYIAQKIYSAVHRLIA
>A0A3R6ZB64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces invadans|TrEMBL
MKIIDKINDKIEKKEAFYSFEFFPPKTPAGVTNLYSRMDRMALLEPLYCDMTWGAGGSTA
NKTIELSANAQKLSGLEMLMHLTCTNMPKGSIKNALDSAKDAGIQNILALRGDPPRGQTE
FKECEGGFSYAIDLVKYIREEYGDYFCIAVAGYPEGHSDADDLDTDILHLKEKVDAGADF
VVTQLFYDVKNYLKFVDKCRAVGVTVPIVPGIMPIQNCNGFVRMSTMCSHVPEEDNDEAV
KEYGVQLGIHMCKELLAQGVPGLHMYTLNLERSTRLILEGLGLTATARRELPWRPSTLAK
RAGESVRPIFWANRPKSYLDRTANWDEFPNGRWGSSESPAFGELNESYYLHATASVQERK
AMWGENPVTYEDVYETFTRYVMGAVKSLPWCDTPLHLETKSIQERLAAVNRAGYLTINSQ
PRVNAAPSDDPMFGWGGPGGHVYQKAYVECFVSPENLKRIIEKCNKMKHVQYHAVDVHGN
SYSNCGKGTTAVTWGSFPNKEILQPTIVDTDSFMAWKDEAFSLWLSMWASLYNDESPAHA
LIHQIRDTFFLVSIVDNNFVNGNIWDAFDVDVTTSSASAAGA
>A0A7S3UD75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Picocystis salinarum|TrEMBL
MDKMVAAGPLFCDITWGAGGSTADLTLDITKQMQNMICVETMMHLTCTNMPKEKLEHALQ
ALQECGVQNILALRGDPPKGQETFVAAEGGFSCALDLIKFIRDKCGDVFGIGCAGYPEAH
PDVICEDPEQMAKNYHSDLMYLKEKIDAGADFIVTQLFYEVELFLKFVKDCREIGINCPI
LPGIMPIQSYGGFQRMTGFCKTKVPQFIKDALEPIKDNDEAVKAYGIQLAVDMCRRILDS
GASPGVHLYSLNMDRSVMAIVEQLHLTGESKIQRPLPWRPPTSTKRNGEMVRPIFWANRP
KSYLQRTENWDSYPNGRWKESSNAAFGTLSESKLIRPKALRVKESKMQQWGEELSSIDDV
QAVFSKFCKGEISYLPWVESEGGLQSESKILIDQLVTLNTSGFLTINSQPRVNGAPSSDP
KFGWGQPNGYVYQKQYVEFFCTKEKLLTLKKKMANLPNLSYQAVNAKGEVLSNISEADVN
AVTWGVFPASEIIQPTVVDPKSFLVWKDEAFSIWLSVWASAYEEGSRSRQLLQEIHDTYY
LVNIVDNDFVQGDLFSLFA
>A0A0U2W348|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. 32O-W|TrEMBL
MKPDLREALQTRILIGDGAMGTYLYQMGFPVGVSYEEFNTLRPDVIEEVHRRYYEAGARV
IETNTFSANPENLARYGLEDETEAINRAGVSVARAAVGADAYVVGAVGSIRAGKRQNIGI
PELERSFRRQIGALIDEGVDGILLETFYDLEEMALALRIVRELSGITAICQFAVEETGRT
RDGVKLHEAFEQLRDGGADIVGFNCRTGPNGILRAIDRIEAPVSLPLSVYPNAGIPDYVD
GKYSYTASPEYFADMARRFADRGARLIGGCCGTTPEHIAAVAASLAGYVPQPPQPGEAEH
RGDRQKKAAEIAPTVPPVSQPELHVTKIEEPPLTTLVRKRHTVIVELDPPRDLDIRKFMA
GAAALKAARVDAVTMADNSLAVTRMSNLALASLVKERLGLRPLVHIACRDRNLIGTQSHL
MGLDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGIAFSGKPLKQKA
NFVIGAAFNPNVRNLDKMVKRMERKVETGADYIMTQPVYDAGLIARIAEATQHIKVPIFI
GIMPLASGRNAEYLHNEVPGIQLSDEVRRRMAGLEGEAGRAEGVRIAEELIDAALPHFKG
IYIMTPFMFYDMAVRLTEYVWKKTER
>A0A257UWQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 37-65-4|TrEMBL
GANPVKLGHYGLAEETAAINRRAAELALEAAGARALVVGAIGPLGIRLEPFGETSRLEAF
ELFRKQALGLLEGGVHGFVLETFSDLDEIHEALRAVRAVCALPVFAQMTIQEDGATAYGS
EPEAVARALDEFGADVIGLNCSVGPQGVLEAIERMARVTARPLSAQPNAGLPRQVGDRKI
YMASPEYTGEYAKRLVEAGARFVGGCCGTTPEHIKSVAAYVQSVSPRQVVTIAAEPVVAP
SGVEPVPLAQRSRWGRKLAAGAFLTTVEIVPPRGVDPTHMLAGARLLKDAGVDAINVPDG
PRAQSRMGALMSALLIEREVGIETVVHYCCRDRNLLSMLSDLLGAAAHRLRNLLIITGDP
PKMGPYPEATGVFDIDSIGLTNLVHRLNHGLDPGGNPIGAPTAYVIGVGVNPVAVDPERE
LRRLAWK
>A0A7C7ETP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKTSELFKRKTVLSYEVFPPKPTAPVNTIYDTLDKLRELSPDFISVTYGAGGGKNNNETL
KIASEIKGYSIESVAHLPCIGLTKKDVAEKLRELNRIGVENILALRGDIPKDGYVQGNFR
YACELIEFIKTQGDFDITAACYPEGHMECRNKVEDIQNLKCKVDAGADHLITQLFFDNDY
FYSFRERCQLAGIDVPIEAGIMPVLNKKQIERMASLCGATVPKKFVVMMERYENNPIAMR
DAGIAYAVDQIVDLIAQGVDGIHLYTMNNPYIAQKVYEAVHNFI
>A0A8G0JQ42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. CJ11|TrEMBL
MVQVSFEFYPPKTDEQRAQLDRTVAKLKPHAPDYVSCTFGAGGSTLTYTSETIRHLRTKH
QVDAVPHISCVGGSREELRALLAEYRDLDCRKVVALRGDMPSGMGRMGELQYASDLIALV
RKEHGDYFKIAVGAYPETHPQARDAQADLQNFKRKVDAGADVAITQYFYNADAYFRFVDD
VRRLGVNIPIVPGIMPIANFSQLRRFSESCGAEIPRWITQRMQGFGDDAAAVREFGADVL
AALCDRLIQGGAPALHFYTLNLARPTLAVLERLA
>A0A7S3UE74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Picocystis salinarum|TrEMBL
MERRRGTRRRRKRTRRWTCAEPPGEGSAAKENLDTKERSTKTWWDWTWLRRVRNGEGRSE
SMERRAKEGWEQDGGMESKGGMEPDTRVSAAPRARANYGSTGTRLQVIEKIHQAMEEDRK
FFSFEFFPPKTEEGVENLFVRMDKMVAAGPLFCDITWGAGGSTADLTLDITKQMQNMICV
ETMMHLTCTNMPKEKLEHALQALQECGVQNILALRGDPPKGQETFVAAEGGFSCALDLIK
FIRDKCGDVFGIGCAGYPEAHPDVICEDPEQMAKNYHSDLMYLKEKIDAGADFIVTQLFY
EVELFLKFVKDCREIGINCPILPGIMPIQSYGGFQRMTGFCKTKVPQFIKDALEPIKDND
EAVKAYGIQLAVDMCRRILDSGASPGVHLYSLNMDRSVMAIVEQLHLTGESKIQRPLPWR
PPTSTKRNGEMVRPIFWANRPKSYLQRTENWDSYPNGRWKESSNAAFGTLSESKLIRPKA
LRVKESKMQQWGEELSSIDDVQAVFSKFCKGEISYLPWVESEGGLQSESKILIDQLVTLN
TSGFLTINSQPRVNGAPSSDPKFGWGQPNGYVYQKQYVEFFCTKEKLLTLKKKMANLPNL
SYQAVNAKGEVLSNISEADVNAVTWGVFPASEIIQPTVVDPKSFLVWKDEAFSIWLSVWA
SAYEEGSRSRQLLQEIHDTYYLVNIVDNDFVQGDLFSLFA
>A0A542RM24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus sp. AG162|TrEMBL
MTTRKKDLRAYLKDHLLVGDGAMATQLHGLGVPVGVSFEELCLSNPRLVHEVHTSYYQAG
ARFLETNTYSANRDALSRYGLEHKVARINRLAVAIAREAAQDDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGVDGVILETFLDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYALTDAFSELKAAGADVIGLNCRLGPAELLRSFENTVIPEDALLSVFPNAGRLG
MTDGEYAFKSSPEYFGQSALRLREQGVRLIGGCCGTTPAHVKAIADALESLEPQVRVNPT
IVAGERPSISVQNTREREKPSIVERVKTATTIIVEFDPPRDLDADQFLHGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKSRHGIDPLLHIACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMDAAVSRLEKKVEAGADYIMTQPVYDAESIRNVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSTEALERMKKVQGEAARQEGIAIAKELVDTAVRYFNGIYLITPFNYYE
MAAELIQYTRQQSSLVKIAQT
>A2TZU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. MED152|TrEMBL
MKITEHIKKANEKTLFSFEIIPPKKGKSIEDLYANIDPLMEFKPPFIDVTTSREEYVYVE
KDGLLDRKVTRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMSHQKYFEASKGGHQYAINLVEQIQNLNRGKYLHDVIESDNCADFCIGVAGYP
EKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVDAAKSMRINIPIIPGIKP
IAVKKHLQLLPQVFRIDIPEELIKEVDSCKSNKEVRQVGIEFAIQQSKELLEAGVPVLHY
YSMGKSDNIQAIAKELF
>A0A1H0VYN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. ok909|TrEMBL
MFPTRIEIIPSEGIVEQVTALVPLSTTLTVTCLPHHGIERTMRAAVQLSLHGYSVIPHLA
ARSLPGRVELTEILRDCDVAGIGEVFVIGGDRKQQAGPYGSALPVLEDIAQYTGGVMRAG
VAGYPEGHPSVGALDLVDALLAKQHLATHVVTQMCFSAPKILDYAALLRREGVQLPVWAG
VAGAVPRTKLVSLAAQIGVGSSLKFLSRKGPLARKLLSGDRYSPQSLLTDLQSQPGSIAG
IHLYSFNNLDAVPDGPDQALTPAALQPALIRRATRDN
>A0A199YQ06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis RTB018|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKVYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>D9XNZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseoflavus Tu4000|TrEMBL
MALGTASTRTDRARTVRDILAAGKKTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVSHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PEALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A1H9EGV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema bryantii|TrEMBL
MIDNSIFDNKTVFSFEVFPPKRSSSIETIYSTLDELSDLSPDFISVTYGAGGSENCSNTL
EIAKRIKKSCNVESVVHLPCLHLSKAEAATMLQQFSENGIENILVLRGDRIEGRAPAGDF
LHASDLSGFIKVTTGNSFHLSAACYPENHPESESIFSDLNNLKLKVDSGCNHLISQLFFD
NHIFYRFIENCRLAGIDAPVEAGIMPVINRAQIERMVSRCGVVLPEKFKVMLDKYGDNDE
AIMDAGIAYAVNQIIDLVSHGVDGIHLYTMNKPVVARKIYEAVKNIISIPKTPALAS
>A0A3C1K5M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MSISSLFKNKKTVISYEVFPPKRDGKLVNLTETIHSLKALNPDFISVTFGAGGNSVDSST
WNIARSIKEDFGIEPLVHLTCLNHSKEDIDNILLRLKGYGLYNILALRGDMNPNIPFKED
FTYASDLISYIDNSGEFSISAACYPEGHLESGNIVLDTLNLKKKVDAGATHLISQLFFDN
NLFYSFLDRTRIAGIDVPIDAGIMPVVNKKQIERMVSLCGASLPPKFRRIIDKYEDKPEA
LRDAGIAYAVDQIIDLISQGADGIHLYTMNNPLIAERIYSGFSSLIR
>A0A3D2HX59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MRITELFDNGEFVVTAEVGPPKGIHIGGMVEEAKEYLAGVHFVNVTDNQSSVMRLGSLAT
CKMLKDAGLNPIFQLTCR
>A0A6L9SCE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytoactinopolyspora halotolerans|TrEMBL
MKPHIPGTRYRKERLRLLADARFEILPLRDAETRVDQLPTGTTVTVTASPRRGIDATVAL
TESLAARGYAAVPHLAARQFIDEAQLHDVLSRLERAGVADIFVVGGDAATPAGMFGDGLD
LLKAIDARGREFARVGVPAYPEGHPAIDDETLWQTLVSKQAYADYIVTQMCFDADTISRF
VLAARERGVTLPIVAGIPGVVGAAKLVRTGARIGVGDSLRFVRGNRAILRRLFGAPYRPE
ALVRKLAAHQVDGFAEPGEEQYVLDAARGRWSPRPKPVPALHGLHIYTFNEVAATLRSLE
HLDWRESGAAAEHEGKGMR
>A0A5J4KTG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyobacter vulcani|TrEMBL
MQTHYPFLERLRNGPLLGDGGMGTELYARGISYERCFEHLNLTNPELIKSIHLDYVAAGA
QIIETNTFGANRYRLAEHGLETQVVEINRAGAKIAREVRELSEQPIFLAGNIGPLGSPLA
PIGTIQPADARAAFAEQTEALLQAGVDLFIIETMSDLAEMREALMAVRSITDLPVVALMT
FGEDGTIVSGEDEQVVAETLRDLGANVFGVNCALGPASMFDVAKRMCTYSNDNFFVAVQP
NAGLPRRVGNRFIYVSTPEYFAEYTRRFLHIGIRMIGGCCGTTPGHIAAMHEVLTELAPT
IAPEAELSANAPTLEAFRERIQENAAQNAESEPAPTLLAARLQEKQFVISIEMSPPRSVK
FTRFLQNAAFIRDSGADTINITDNAMARVRMNNVAAARLIQQNVGIETIVHFTPRDRNLM
AVQSDVIGAHATEIRNILAVTGDPPSHGDFPNSTGIWDVDSIGLISILSNLNKGLDGNRR
KLAAASSFFIGCAANPAATELDIELERLHRKIEGGAQYILTQPVFDAGTFLHYIRRYKDQ
YGEIPIPILIGLQPLHSYQQAEKFHNEVPGIVIPEEIRQRLRQAGEGGGAVGLEIIKELF
EKLQSEVQGTYIMPLDRFELIEDLIPYIRQRTTK
>A0A7W7WKR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora gansuensis|TrEMBL
MALGIPSTRTDRAETVRDLLAAGDRSFSFEFMPPRTEAGEAKLWDAIRRVESLDPNFVCM
TYGAGGSSRGRTVNLVGRIATETTLTPVAHLTAVDHSIAELRNIIGQYADEGVRNVLAVR
GDPPGDPEGEWVRHPQGVEYAYELVELIKSIGDFCVGVAAFPSMHPRSESWDDDIRHFVA
KCRAGADYAITQMFFEVEDYLRLRDRVEAAGCSTPIIPEIMPVTNIRQLTRFPQLSGSAF
PVELQRRFEAVAEDPEAVRAIGIEHATAMAERLLAEGAPGLHFITLNHSTATLEIYQNLG
LHQR
>A0A7C2JVI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSKLKDKIEAGQFVITAEIVPPLSAASAKLLHEASQLKGRVDAINITDAAAGKTSISSFA
AAALLVADGYEPILQVTCRDRNRIALAGDLIGAAAQGVENLLMLRGDDPKGGDQPDAKPV
FDFESIDLLKLARDMRDKGELPSARKIDSPPKFFIGAADVPRRPDAKWSPVPLQKKIEAG
ADFVQTQFGFDLDVVRAYAERLRAEGITEQLGVIIGVGPIRSAKSARWMNENLFGVTVPE
PIIARIEAAKDQAAEGRRVCAELIEGLKEIPGIAGAHIMAPAQGTGAIAAVLDSLD
>A0A2J8USM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pongo abelii|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLH
>A0A833ISF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalilimnicola sp. S0819|TrEMBL
MQSQKLHAPVFSFEFFPPKTDEGAAKLRLTRERLAALGPRFFSVTFGAGGSTRDRTFETV
CEIQRESGIDAAPHLSCIGSTRENIRDILRQYQAEGIRHIVALRGDLPSGTMEAGEFRYA
NELVEFIRAETGDYFRIEVACYPEVHPQADNAEVDLANFKRKVEAGADAAITQYFFNADA
YFRFVDACEQQQIDLPIVPGIMPILNYKQLARFSDACGAEIPRWLRKRLEAFADDRESLV
DYGVDVISEMCRRLLDAGAPGLHFYAMNQAPVTERIWHRLGLGERPSRSARV
>A0A6N8ZJZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSVTLRDLIADGRAHVVDGAMGTMLYGKGVFVNVCYDELNLSTPEIVREVHEEYVHAGAE
ILETNTFGANPVKLSGFGLEERTEAINRAGARLARDAAAGRATVVGAMGPLGIRIEPWGA
TAFEEAVAFFKRQARGLIDGGVDGFCLETFSDLGELEAAFRAVRSLADLPVLAQVTIGDN
GATPGGTTMEAAGAAMAEWGVEVAGINCSVGPAIMLDAVERLAASSGLPASAQPNAGLPR
VVENRQIYMASPEYMGQYARRLVAAGARFVGGCCGTTAAHVRRIRDHVASVQPVRVRAAA
RGGAAERTGRSAVPLADRSAWGRKLATGRFVTTVQIAAPRGWRMEEITRQARALATDGVD
TVFVVGGTRGQAHMGALTTAMLLGDRAGIEPLVRYVCRDRDMHGMISDLLGASAAGIRNL
QIVSGESTDLGPYADSTAISDIDSIGLVNVVHHLNRGLDAGGNDIGAPTELVAGVGLDQA
AVDQDSELSRFAWKVDAGADFAVTRPLFDPGRLEDFMARADTDIPVIATLLPLSSLRNAE
FMANEVPGVEVPEGIVQRMRAAERRSPAHARAEGLSIAREMFAGVRHLVRGVRVRLPDDD
LSRAAQLLSRL
>A0A6G7YIU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides piscis|TrEMBL
MELQQRIIDGRGEFLLFALTPPRQTASPERAQEIADITVKRLESLEVDGLVLYDIDDESD
RNPHERPFPFLPTMDPADYLSRYFDVGNIPVVVYRAVGKYAEADLESWLRAQDPARRLSV
FVGAASRDKPVTTSLGRALTLRAQTRPDLLLGGVAIPERHARSGDEHLRLLRKQAAGCSF
FVTQVVYDVTAAKNLVSDYRYECLAHGVSPAPIVFTFSVCGSTKTLDFLRWLGVDVPRWI
ENELLHADDTLEASFEYALTAARELMAYCRRLGVPFGLNVESVSSRRDEIEASVDLAGHL
RGELHRQD
>A0A7X4X527|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. V30_P3S12P165|TrEMBL
MGYTHASHIDALNQSISEVSDINVSFEFFPPSTPKMEETLWNSVHRLKNLNPKFVSVTYG
ANSGERDRTHSIIKAIKEQTGLIAAPHLTCIDASRDELITIADDYWHNGIQSIVALRGDI
PLGGGKPEMYAADLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPQWMAKQFDG
LDDDPVTRQLVGASQAIDMIRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPR
>I4AHA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bernardetia litoralis (strain ATCC 23117 / DSM 6794 / NBRC 15988 / NCIMB 1366 / Fx l1 / Sio-4)|TrEMBL
MKVIEHLNTNKGKTLFSFELIPPLKGESIQSIFDAMNPLMEFNPPFVDVTYHREEYVYKI
REGGLLERKVTRKRPGTVGICAAIMNRYQVDAVPHIICGGFSKEETENALIDLSFLGIEN
VLALRGDAVKSEGSFIPEKDGHNYAVDLIGQIVDMNKGDYIDDDLPHPIPTNFCIGVAGY
PEKHFEAPNLNSDMNALKAKVDAGAEYIVTQMFFDNAKYFEFVEKCREFGINVPIIPGLK
PFTTKKQLSVLPRIFHIDIPDDLVTAVSACKDNKAVVEVGIEWAVQQSKELMKKDVPCLH
YYTMGRSRATEKIAAQLF
>A0A2J8USL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pongo abelii|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQ
ELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFW
ASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTS
EESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPN
INGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGEN
ITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKVVEDTLELLNRPTQNAREMEAP
>A0A378MB32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria grayi|TrEMBL
MNLRRDLNEKVLIADGAMGTLLYSYGIDRSFEELNLSHPDDVSGIHRAYIEAGADIIQTN
TYGANYIKLSRYSLEDEVKKINQAAIRLAKEAARGTGTYILGTMGGINGSSDTKLPLASE
EEVKRSFREQLYCFLLEGVDGLLLETFYDVDELKTVLKIVRETTDLPVIANVSMHEPGLL
QNGQQLPEVLKELEALGADCVGINCRLGPYHMARALETVPILQKSHLAVYPNASLPEVRG
GKVVYHTETEYFQNYGEIFRQEGARIIGGCCGTTPEHIRALREGLKSFEPVTSKKVRPII
ELVPAEKLEDDGEERLLDKVKREHTILVELDPPRTFDTDKFFEGAEALHENGVDAITISD
NSLASPRISNMALASILKHQYGIKPLVHLTTRDHNLVGMHSHIMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKYNAGISYTGKSLKEKGRFHVAAAFNPNVLNVEK
AVKLIQRKVEYGADYIITQPVYDKEKIAILKDALQKADIKVPLFIGVMPLLSGRNAEFLH
NEVPGIRLPNEVRERMREAEAADRSKEEGMKIAKEIIDSIYTEFNGIYIITPFLRYDLSV
ELATYIQNKKRPMCLKNSRVSFLIQ
>A0A095XSZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium periodonticum 2_1_31|TrEMBL
MKIADIYKGKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIADRIKNQNGVESVAHLTCIGAKKEEIDKVLEDLEKHNIENILALRGDYPVDRELEVGD
FSYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A1Q5U6U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus thuongxuanensis|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLDAAPHLTCIDASRGELSNIAHDYWQNGIRHIVALRGD
LPANGCKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFASMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A534BYA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MATILWDSIERLAPLAPRFVSVTYGADGSTRQRTHDVVTRIQRDTALTGAPHLTCIGASR
GEILAIARGYWSQGIRHLVALRGDPPQGESPHRPHAADFRYAVELVAALAAVAPFDISVA
AYPEVHPEARSAAADLDNLKRKIDAGATRAITQFFYDTSVFLRFRDALAAAGVHAPLVPG
ILPITRFPQVRRFAERCGASIPRWLHERFAGLDD
>A0A257QRP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium 20-60-12|TrEMBL
MTHNPNRAVLQRWLAGPRIEPLPARSANAPAPAISFEFFPPKTEALEAQLWTCIRRLEKL
SPRFVSVTYGAGGTTQERTHATVTRIVKETALIPAAHLTCVGASRGEVDDVARLYWDAGV
RHIVALRGDPPPGEAFTPHPQGYAYAVDLVAGLKRVADFEIAVAAYPETHPQAISADADL
DNLKRKIDAGASHAITNVFFDNDVFLRFLDRCLAAGITAPIIPGIMPVSNFAQIARISAM
CGASIPSWMGAMFDGLDDDLETRRMIAAAIAAEQVRLLQANGIDEFHLYTLNRADLSFAI
ARILGVKSTP
>A0A5J6V6C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ornithinimicrobium pratense|TrEMBL
MTSTQSRISVELVPRSVESVRTEMAQVRAHLPWVDTINIPDLLKFELRSWEATRVAGQAV
RRPDGTAYRRIPHIRATDVNPDAPLPMGQDLLDQGVDEVLVVSGDHGDYFTHQTYPVDAV
DVIRRFRAELPQLRVYAGLDPYRTGIAQEMRYLERKLAAGATGIFTQPFFDTHLMAAWAG
ILPRGVEVWWGATTVTTKGAAGYWRRRNLVAFPTSFAPTIEWQRDFARRAIDFARERDQH
IYLMPVRTSVTDYLAGVL
>A0A521H8S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPPISFEFFPPKTDEQRASLESALPRLKAYTPEYVSCTFGAGGSTLSYTPDTVRRLREVH
GLDAAPHLSCMGGTRDEIRGLLSDYRSMGCKRIVALRGDLPSGMASHGDFRYASDLVEFI
RAETGDHFHIEVACYPEVHPQSNDALSDLDNFKRKIDAGANGAITQYFYNADGYFRFVEA
ARALGVSAPITPGIMPISNFSQLRRFSDMCGAEIPRWLGKRLSAMGDDVESIRAFSADVV
AELCRKLISGGAPGLHFYTLNRAKPTSAVLERI
>A0A094PU99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|actinobacterium acIB-AMD-6|TrEMBL
MSNDQSAPTLSVEFFPPKDISGEERLWQVLAQLAPLKPDFVSVTYGAGGSTRDRTIRVTT
EITARTSIPTVAHLTCVGSTKSELSKVLDQYKKAGIESILALRGDPPGGPRSNWQSIPGG
FDHADQLVELAIESKDLKVGVAAFPDGHPSSNFDLDKDIEVLLRKEELGASFATTQFFFD
VNKWQQLVERLRKRGSKLPIIAGILPITNLKQLNRMVELSGMQIPEQILTRFKDHSEDVN
VVREIGIDIATEMGSKLLEMNVPGIHFYTMNSADSTIKIARNLGMVKR
>A0A1F4A0K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_64_12|TrEMBL
MSPPDSADPAELLRRAAALRGLVDAINLTDGAGANCHMSSLAASAVLAANGYAPVFQIAC
RDRNRIAIQGDILGASALGVRNLLCVTGDSVGNGDHPDARDVFDLDAVSLLEIARGMRDR
GTYASGRRLGARPALFLGATSNPFAPPFEARVINLEKKIEAGAQFIQTQYCFDAPLLQSF
MREARARDLHRRCRILVGVGPLASARAARWMVAHVPGVHIPEGVIRRMEQSKDAAREGVR
ICAEIIGEMRAIEGIAGAHIMAHRREDLVREIIAEAGIASVPAPDPRGIPLNSHAGGA
>A0A258NEQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. 35-64-16|TrEMBL
MTAANAPSTGLPVSFEFFPPKTPEGAEKLRAVRQQLYAQRPEFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREELATLKAMGVRRLVALRGDLPSGYGIGGEFHH
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSADADLQAFAAKVRAGADSAITQYFFNAD
AYERFVDDVRRMGLDVPVVPGIMPIMGSSQLMRFSDACGAEIPRWIRLRLQGFGDDTASI
RAFGLDVVTSLCEQLRQRGVPSLHFYTMNQSATTLEICRRLGL
>A0A3D0SQY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
NSAITQYFYNPDAYFHFIDQCARRHIGIPVVPGIMPITNFTQLARFSDACGAEIPRWIRK
KLESFGDDRNAIRAFGLDVVSELCRKLLDGGAPGLHFYTMNQAGLTLAIWERLGFTTSR
>A0A534CZ08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MATILWDSIERLAPLAPRFVSVTYGADGSTRERTHDVVTRIQRDTALTGAPHLTCIGASR
GEILAIARGYWSQGIRHLVALRGDPPQGESPHRPHAADFRYAVELVAALAAVAPFDISVA
AYPEVHPEARSAAADLDNLKRKIDAGATRAITQFFYDTSVFLRFRDALAAAGVHAP
>A0A3C1PRM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MLDSFETCYLYLFIPRLGHYHMTVSFEFFPPNNGNFARVGDHLDKLLKFGPKFISVTFGA
GGSAENKSVELIEELSSRSATEIVAHLTLVDKTKDRIAQITQQFRKLGIKTILAVRGDSP
NQEYQSIEGGFQDTSEFVNHLKNQGFNVCVSAYAEPHPESPDIEFDFELLKKKVDAGATT
AITQFCFELNKLEDLKNALAREKVAVDLIPGVMPVRNINNLKRMADRCGINIPRNIATRF
EVSEDEQRKVAFDLAVEQVATLKQIDFDSFHFYTLNQSSLMEDLLAAI
>A0A534B9N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNAESARTPIRVSFEFFPPADEAMGAMLWKSIERLAPLAPRFVSVTYGADGSTRERTHNV
VTRIQRETPLTGAPHLTCIGASREEILEIARGYWDEGIRHMVALRGDPPRGEGARRPNPR
GFRYASELVAALAGLAPFDISVAAYPEVHPEAGSAAADLENLKRKIDAGATRAITQFFFD
TDAFLRFRDALAAAGVHAPIVPGILPITRFPQVLRFAKACGTSIPGRLHERFAGLDDDHE
TRRMIAASVAIEQVEALRRHGVSEFHFYTLNRAELTYAICHALGLRPHARSASAALQEAR
A
>A0A349X6U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTQSPDLHQFVEEPGSPLAPRAGHVSLGRFERVLREGHFAVTSEIAPPDSADPDEVLVRA
MVFDDVTDAINATDGSGANCHMSSVAVCSLLSRVGYSPILQISCRDKNRIAIQGDILGAA
ALGVCNVLALTGDDVSAGDHPEAKPVFDLDSVSLTTTICHLRDKSQFLSGRAIDTAPKMF
AGSTINPFVPPVQSRLAQLRKKINAGAEFIQTQYCFDVDVLKDMMARAVDEGLMEKAYMI
AGVGTLASAKTARWLRSNVPGVSIPDHIIERLEGAKNQKLEGQKICVELMQQCKEIVGVS
GVHIMAYKQEEYVKEMVIASGVLDGRVCWAPGR
>A0A2A4RJN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSIDNRSATMSCEFFPPRTAAGVEKLLATRQTLDAVIQPTYFSVTFGAGGSTRDSTLELV
KLLSEQKVNVAPHISCMCSSKQQLETLLNEYKTIGVSRLVTLRGDVPIAVDDTDETPNKT
VTELSHANDLVSFIRDTTGDHFTIEVAAYPEYHPESASPQSDFEHFKNKVAAGADGAITQ
YFYNVDAYYRFMDNCEQANISIPITPGIMPITNFANLTRFSDTCGAEIPRWIRKQLEVYA
DDKESLQAFGLDVVSNLCNQLLEQGAPGLHFYTLNQAQSTNAIWKNLSI
>A0A660LGZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacter pauli|TrEMBL
MGAMRIDERIASGTEPAFSFEFFPPKTDEGEANLETALHELARLEPTFVSVTYGAGGTPA
ERGKTIDIVSSIKATHGLEAMAHFTCVGASVDELRAVLDRMRDAGIENVLALRGDPPAGV
DAKNWVAADGGLRYSRELIELIRADYDFAIGAACFPEVHLAAESAESDLRYTREKVDAGA
RFLVTQLFFDNDLYYDFVARARDAGIDVPIIPGIMPITNVKQVKRFTEMCGATIPPGLLR
ELELRSDQPDAVADFGVAYATMQCADLLANGAPGIHFYTLNRSPSTRAILSALRCLAPWR
KAVSA
>A0A3R7UFP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium TMED126|TrEMBL
MNLYKGQRKIQLKLKSALMINSNLNNSTIQKSFEIVPPRYSISDSFINKIIKHEKSFDLL
DITCCPMATLRVNPIAVAHRLILKGIKPEKLIVNFSSRDRNSLALQSEIFGALSIKLKNI
LIVKGDPIRYGNSKNSKEVFELTTDQIINKVNNINKGFDFNNNETNSKNYIDIFSTLNIN
RSFNEIKKTIQKRLRKGSKFFITQPIYSESDFEKIIKLSKSKDYKIFAGILPIKNKKILG
NLLKKLGGITIDSPHLVELAKYDDKKIHSHSSKHLKKLIKVYKKNLDGLHLMTSGSINEA
SNLIKDL
>A0A349EH23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGSPTNFSCEFFPPVTAEGLGKLQAARQQLLALRPAYFSVTYGAGGSTRDRTVEVVLDTQ
AHSGVPAAPHLTCIAATRDSIRELLNHYKTHGIRRIVALRGDMPSGMRDPGEFRYANELV
SFIRAEFGDDFYLEVAAYPEYHPQAASPEKDLENFKRKIDAGASSAITQYFYNPDAYFRF
VDRCAGLGITIPIVPGIMPITNFTQLARFSDACGAEIPRWMRKTLESFGDDREAIRAFGL
DVVSELCRKLLEGGAPGLHFYTMNQAGLILTLGERLGWIAR
>A0A3M1DSU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTENGLALSFEFFPPRTPEAKGKLQTTIARLAKLGPDYCSVTFGAGGSTREKTFETVVGI
ERETGIEAAPHLSCIGLSLEEIRETLERYREAGIRRLVALRGDLGSGNIGGGPLRYANEL
VEFIRKETGDHFIIEVAAYPEVHPQARSAREDLLNFKRKVEAGADGAITQYFYNADAYFR
FVEDARRLGVEIPIVPGIMPITNCSQLVRFSEACGAEIPRWILMRLRDFGDDRAAIREFG
TEVTIELCRRLLEGGAPGLHFYTMNQYQATEAIWRALGLRQQEARASA
>A0A3D3XSJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSQPQISYEFFPPHTKAGITKLVETAQVLAATDPAYFSVTYGAGGSTRTRTYETVVKLME
>A0A3C0YGD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MFESQNFLFTAETTPDVSTDLAASAGRVDDLVGVADAINVTDSPNSKTRLSSLLVAAEIR
RKGLDVILQLTGRDRNAIALESELLGALSAGVNKVLCLTGDQPPEGGPKAVNEFNGAGLI
QLCNTLSQGTLSDGTPIKAAKTVYPGAADDIYQHLDNENAAAGLLRKIEDGAGFVQTQYC
FDLDVIKAYAKKLSETPAFKDRKVLVGLGPLASAKQADWMRKNLWGVNISDDIVQRLEQS
HEPMREGEAICEELIGELMQLPEIGGVHLMGPNCEKRSARIIARFRS
>A0A3D5Y4I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MHLDDQAVPSTALPVQPGYSSSGRLERVLRAGSFAVTTEIAPPDSADSAEVYRRAGIFDG
WVDAINATDGSGANCHMSSVGVCSLLTRKGYATVMQVSCRDRNRIAIQGDVLGAAAMGVS
SILCLTGDGVQAGDQPDAKPVFDFDCMSLLQAVAAMRDRSELMSGRPLTVPPRVFIGAAA
NPFAPPLDYRPLRLQKKIEAGAQFVQTQYCFDLDRLTRYMRQARDLGLDERCFILVGVGP
LASARTAAWLRDNVPGVHIPDAIIKRLLEANDQKEEGIRICVEMIQAIREIEGVHGVHVM
AYRQEHRVPDIIRASGVLAGRVPWYPGCTEISPQ
>A0A2E0CDX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MATYVSDEKGLIDYGVEVVTKLCERLLEMGAPGLHFYTLNRWGASSRICRNLGFLER
>A0A1F2W430|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium RBG_13_35_12|TrEMBL
MIHHIQNKIYHIEVLPPKQDSEKLEKDLEIFSNKYLRVMDSSYCTCITDNTMGLLSFQGT
EIIEELDLPVMSEQVMIHLNTFHTKDDLDNILDICKAKGIRYLLIITGDGSERLPKLQPS
DVGATDVESVTSVELLKYINHEYPDTFILGAAFNPYEPEEHEFEKMKRKMKAGATYIITQ
PLIERNEVVDRLLEKYPEIPVIIGTWMSRKLHLLSEAVGYEIPENAEYDPISTLKMLHKL
YSGCGVYLSLLGFKTQYDLIKDIWV
>A0A2G6L277|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNTSTENTKNISFEFFPPKIEAGIKKLKTIREEFSKVNPNFFSVTYGAGGSTRDRTRETV
IETQNQTGIETAPHLSCVGDTKEELRELINDYKSKGIKRIVALRGDLPSGMGASLGELKY
ASDLVTFIREESGDHFHLEVAAYPEMHPQAANMHADLQAFKTKVEAGADSAITQYFYNID
AYKFFVDSCEKMGIDIPIVAGIMPIINYENLMRFSNSCGAEVPRWIRMRLEAYQNDLESI
RQFGEEVVTSLCEEVLALGAPGLHFYTMNQLNPSLSIWRNLNC
>A0A353D3P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTDNNKTTFSLEYFPPRSAKGEEGLAVARADLKLLNPAYVSVTFGAGGSTQDGTYATIKS
IMENDGVDAAPHISCISTDRETLARMLGEYRELGVKRLVALRGDLPSGYGTTEAAELRYA
SDLVAFIREQTGDWFKIEVAAYPEFHPQARSAQDDLENFKRKAEAGADSAITQYFFNPDA
YFRFIDSCTAMGIDIPVVPGIMPITNYKQLARFSDACGAEIPRWIRKRLEGYGDDLTSIR
DFGFDVVFTMCERLLDAGAPGLHFYSMNRTEPTRGLWKALNLGQQI
>A0A2E3UPU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MELNPKPIFSIELYPPRTTPDESKLDEVHDQLASLEPDFFSVTYGAGGSTKQGTKXIILK
YQQLGSNMVPHLSLGGTDRDDIRILLTAYKAAGINHLVALRGDLPPNTTTPVQHQYASEL
VEFIRLETGNHFHIDVACYPEPHPDSTSYKSDIAYFKKKIDAGANSAITQYFYNADAYFY
FVDYCSKAGISVPIVPGIMPINNYTNLKRFSAKCGAEIPHWLQKRLEGFEGDVEGLKEFG
IEVVTTLCERLLAGGAPGLHFYSMNLAKSVNQIWKNLALSDRS
>A0A2E1SXJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSEQIQFAMQNWSIEFTPSNKTKIDDFRRVLPIGTTVNVTAIPGTDPALMMATVEQLATQ
EMNPVPHIAARGIASISVLENXLASYREVDVTEILLIAGGYQSPVGDFKSAIEVLETGLL
QXVGIRKIGVAGHPEGSPDIPEXELKKALKQKNXFAEETGIAMYLETQFCFDAQAILRWE
SEIRADGNXLPIRVGXAGPAQXKTLLHFALISGVXPSLQFLKKQALHVTKLLSVQDPYDL
IADLAPHVNEHSPTQLQSLHFYSFGDFSQTARFAHELAMSGTR
>A0A1P8MVC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tateyamaria omphalii|TrEMBL
MPTPDVALSFETFPPKSLDASFHLWDTVQALTPLNPRFVSVTYGAGGTTQSLTQEAAQTL
RKTSGLPVAAHLTCTGQSRDDVLATAQRYAKSGVKDIVALRGDAPGGGSFAPHPDGFANS
IDLIRALADMGQFTIRVGAYPDSHPDATSPQQNIDWLKAKLDAGASEAITQFFFEPDSFL
RFRDACAAAGIIAPITPGIFPVANWSRAKKFAESCGTPIPVATATAFDRAEREDRAHLFA
LTHCADLCDTLISEGVDKLHFYTLNRPDLTLKVCRALGLVRPTQMRNVA
>A0A673IAJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus rhinocerous|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAETFLRF
VKNCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGI
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMFKKHIIFHILYIIVSPLC
PAFLKRVDFYKAHHSEKRGVL
>A0A359LQJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacterales bacterium|TrEMBL
MTTSPGILSKALEFRERLEKGILVADGAMGTMLYGKGIFINRCFDELNISSPQMVREIHQ
EYVKVGAEIIETNTYGASRPRLAAFGLAEKLKDINAAGVKLAREAAGEKAFVAGAIGPLG
VAIEPLGPTSFEEARGHFREQAEALLEAGIDLVVIETISNLHEVREAILAAREAAGKDMV
IVAHVTIDDYGNMADGTDTQTFTQALNELPADVIGLNCSVGPKVMLETIEKMVKISRKPL
SAMPNAGQPAFVEGRQIYLCSPEYMSQYVRRFMWEGVKIVGGCCGTTPEHIKLITSEARS
LQPLQRKLAVTVEEPKTKAKAMEKAPVGAKSKLGAKLAKGEFVSFVEILPPRGVDASKEI
SGAALCARHGIDCINVPDGPRASARLSAQVTCQLIQRDAGIEAVLHFCCRDRNILGIQSE
LLGAHAAGVRNLICITGDPPRMGTYPDATAVFDVDAIGLTNIVNNLNHGLDIGGNPMGSQ
TSLLLGVGANPGALNLDEELRRFEWKVQAGAEYVVTQPVFDLELLEQFLKRTEQFQIPFV
AGIWPLTSYRNAEFMVNELRVPVPEKYMARMRNADSAEKARAEGIAIAREMVEQVQPMVR
GVQLSAPFGRYDMAIQVAEAIRRV
>A0A350UL20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacterales bacterium|TrEMBL
MSQSLKSLSRAAQFRERLSKRVLVSDGAMGTMIYGRGVFINRCFDELNLSQADLIREIHE
EYVKAGAEILETNTYGASRPRLETFGLDGKLAEINRAGVKLARAAAGEKADVFVAGSMGP
LGLHIEPLGPTSFEEARRYFAEQAEVLVEAGVDLVLMETFGSVTELREALAAARAAAGPD
LVLVAQMTIGDDGRLLDGTELEDFTRFLDESPADVIGLNCSVGPKAMFEAVERMLALTKK
PLSALPNAGHPTKVEGRNIYLSSPEYMSQYARRMLWAGVRIVGGCCGTTPEHIRSIRSEA
RSLQPGQRSLQVTVEEPKAKAQAMEKVAVADKSTLGAKIAAGQFVAFVEILPPRGVDPAK
EILGARLCKDHGIDAINVPDGPRASARMSAQVTCQLIEREAGIESVLHFCCRDRNILSIQ
SELLGAHAAGIRNLICITGDPPRMGAYPDATAVFDVDAIGLANIVNNLNHGLDIGGNPIG
SQTALLLGVGANPGALNMDEEIKRTRWKVEAGAEFIVTQPVFDLALIENFLERIREFRIP
VIAGIWPLTSYRNAEFMVNELRVPVPEAYMERMRAAANPEAARAEGVAIAKEMVTQVRPL
VEGVQLSAPFGRYEMAVEVAGVIGPR
>A0A1G0Z7Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_50_93|TrEMBL
MPESKTTTQMEIDFQKQKSGNVFRDRLNKGSFYVLIEAATPEKKEDFAIAAQRLKAVEAS
LGKYDTLGTGLAITDKTHGSNTWNIADFANELSKDDRDCHVLYISGRNATANDIVDTVAR
CRSSGFQNVVPVTGDAYFPEGYRKKHKLNFVDSVCTLNTLKSGGDKDFFFAGCTANPFKY
TPADLFPQYYKMVKKIKQGAEFIVTQSGWDMMKLQELRWYLEMRELHFPSIARFTLLTTE
LFEEIFAGKRPGIHISAELRKILLNEAKYGYAQFASAQWRRLQIYAAGAKFLGYTGIQIS
GVERQEHIATACSKVAEAMREFKSFEDWRDGYLSYLSRADMTPYPYRHFMFNNLFTKAYP
ELATMKKVDLPECGKYEKLHYRMCKLLFSKAHRHSSNEHLLSKKIFTGCRKCSSCRLPFT
QFVCPETCPKGLANGPCGGTRADGTCEFGGKQCIHAKIFRRASWLKDLDSLEERYIKPVE
KI
>A0A2S9TJN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter cryaerophilus|TrEMBL
MFETLISKLQDGKYLTLETTPQHEPSMHNIVEKIKKFKIDSKVDGFTCTDNPLAKLKYNS
LFAALKLQTEFKKPVIATMTMRDRNKIALQSDLLGANDFDIRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFAVVNAYAKNFGSLEKKMNLKI
QNGAVGVITQPVFDIENVKKLLESFEIAKENVEGDKKKSQLILGLFPITKLRTALFLSAQ
VPGIHVPQFWIDELERAHSISEEEEYKVGMHLSKNLFKEINKIHPKIHLMTANNKFEVAS
EILD
>A0A6M1E5I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parapedobacter sp. SGR-10|TrEMBL
MKITDHIKNAKGKTLFSFELLPPAKGQGIQSIFNTMDELMEFNPPFIDVTYHREDYLYKQ
HTNGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDSDFIPTPGGHAYATDLLQQVVDMNNGKYLHEDIVNSEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKIDMGAEFIVTQMFYNVEKYKEFVTKCREQGIEVPIIPGLK
PLTTKKQLIALPKIFHLDIPEELSDAVTACKNNAEVQQVSTEWMVNMCKELIDFGAPVLH
FYTMSNPGPTKKIVEKLA
>W4VNH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gracilibacillus boraciitolerans JCM 21714|TrEMBL
MIKALESVPLLQNAYLAAYPNASLPDYQNGKLVYSQHSQYFTQCAQDFRNQGVRLIGGCC
GTTPEHIRALKEGIKDLKPIEEKEVKALLSITNKNQHKQTNKDSLAEKAKKQHTVIVELD
APKHLDIDTFMDGGVFALENAGVDAITLADNSLATPRISNAAMAIKMKQAGSKVTPLIHL
TCRDRNLIGLQSHLMGGLHTLELDEILAITGDPTRIGGFPGASSVFDVTSFELTKLIKQC
NEGLSFSGSSLKLKTNFQVAAAFNPNVANLEKAVKRMKRKIEHGADYFLTQPIFSHEKII
ELHRLTKDINKPIFIGIMPLTSHRNAEFLHHEVPGMKLSDEVRARMQQQTNRQDGFREGI
EIAKELIDTAINYFNGIYIITPFMHYASTVELTRYVHEKTKLKTKI
>A0A444V7S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acipenser ruthenus|TrEMBL
MVNQVHCTDSNGPLAKYESSGTSSSGGDSSKESSRCSTPLLDSDRTDRLREKMRHRMESG
DRWFSLEFFPPRTASGAVNLISRLSAMVNQVHCTDSNGPLAKYESSGTSSSGGDSSKESS
RCSTPLLDSDRTDRLREKMRHRMESGDRWFSLEFFPPRTASGAVNLISRFDRMGAGGPLF
IDVTWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHITCCNQSKEKISQHLIKAKKLGL
KNIMALRGDPIGNEWEEEAGGFSYATELVKHVRCEFEDYFDICVAGYPTGHPEAKSYEED
LRHLKEKVDAGADFIVTQLFFRSETFLKFLKDCRAIGITCPIVPGIFPIQGYQSLRQLVK
LSKLEVPEEIKEVMEPIKDNDAAIRNYGIDQAVEMCKVLLHSGEVPGLHFYTLNREVATM
EVLRRLGLWLEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWG
NSSSPAFGELNDYYLFYLKSRCAKDALLKMWGEELMSEESVYEVFTCYIAGKPNHNGHKV
TCLPWNDDPLASETNLLKEELEKVNRRGVLTINSQPNINGKPSSDPIVGWGPSGGYVFQK
AYMEFFTSSENVSALLKVLKKYEPRVNYHIVNVKGENVTNAHDMQPNAVTWGIFPGREII
QPTVVDPVSFMSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLES
CLWQVIEDMCKLLDSPVEHPAELQP
>A0A424I4R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibacillus sp. TMED18|TrEMBL
MQNTPHISDLLSQGNPSISFEFFPPKSAEASDRLFSTIHELKQLNPSFVSVTYGAGGSTR
ELTHKLVLRIMEETTIPAIPHLTCVNHSRAEISEILSGYANAEXPAILALRGDPPEENPD
YNRAQDAFCYAADLVSFIQNFNRETSNPRKRFGVGVAAFPEGHPDTQNRLKEMDYLRQKV
DSGADYICTQLFFNNYSFLDFRDRCRLAGIHIPIIAGIMPITTKSGMVRMADLAAGVHFP
AQLQRMLFSAQDDPVAFEKAGTDYATSQCRELLAEGVDGLHFYTLNRSSATAQIATALDL
GQK
>A0A4R4ZEJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea terrae|TrEMBL
MTFELICEIEPPTKPDLKRVRHQIGTLTTIADAFLIPDNHIGRATVSSVAVAHEVEAMGG
RGIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTSGNRTSDLTVRSMIEEAREF
SPEFRLGAAAALRPVPAWKRTADFLFSQVSFSVEAQLRWREAHPVDMPVYAGVMVLASAN
HARGLAAAIPDIDIPGELVDKVSADRMVGVEAACEQVLALRESGAFAGVHLVPVARYRDV
ESRLAGVL
>A0A5D0EMP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aggregatibacter actinomycetemcomitans|TrEMBL
MSYAKEIDNLNQHLADLNGKINVSFEFFPPKSEKMENLLWESIHRLKVLKPKFVSVTYGA
NSGERERTHGVVKRIKQETGLEAAPHLTGIDATSDELRRIAKGYWDSGIRRIVALRGDEP
KGYEKKPFYAADLVALLRDVADFDISVAAYPEVHPEAKSAQADLINLKCKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPAWMSKMYEGL
DDDQTTRNLVAASIAMDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGIRPSL
>A0A090F986|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. ORS 3359|TrEMBL
MTARQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTERLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAQRLDHILHDEITETQVDMVK
TAH
>E3HP54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter xylosoxidans (strain A8)|TrEMBL
MSDSTTPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCEAAPHLSCVGATRQDLRDILQAYKNDGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAASPSADLDHFVNKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVNVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGVHFYTLNHAEAPMAVWKELSLQA
>A0A2J8KXC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pan troglodytes|TrEMBL
MDHRKARVLPAGHYCPSLGIWASQVGSVRSSVPPSIRNPAMVNEARGNSSLNPCLEGSAS
SGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISRF
DRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTA
>A0A517L1F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Venturia effusa|TrEMBL
MHISNRLAEAEKARKPTFSFEFFPPKTAQGIQNLYDRMDRMHGSAHLTCEMVKTAQTALG
LETCMHLTCTDMPVSKVDEALKEAYDAGCTNILALRGDPPREKDKWEATSGGFRYAKDLV
KYIREHYDDHFDIGVAGYSERCEDNEDVDQLVDHLKEKIDAGATFIVTQMFYDVDLFLDW
VRKCRAKGITVPIVPGIMPISTYAAFIRRANGPMRCRIPKAWLEAMEPIKNDDSEVREVG
MRLVAELCQKLLASGEIHHLHFYTMNLEKATRMVIEELGLMPDVGSPVGKPLPWRQSLGL
KRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFGELDAYGIGLKGSNEHYQ
KLWGAPQTVKDISDLFVRYVQGKLESLPWSEQPISQEATSITDDLIDLNRRGILTINSQP
AVDGAKSSDPIHGWGPRGGYVYQKAYLEVLISPELIAEVITKIERDDDMTYYAVNKHGDL
KTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEFFHLGQDWAECHPSSSPSRHL
IETVMENWYLVNIVHNDFHQTNGVFQLFDGLKVDDIDKPFVNPKTFPVHENVNGVSTGLD
AAVNGGTAIAV
>A0A238L045|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria arenilitoris|TrEMBL
MTQPEISFEFFPPQTLEASFRLWDTVQTLAPLAPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLKVAAHLTCVDASRSETLAIADSFAAAGVTDIVALRGDPPKGQERFVPHPDGFAHSV
ELIAALAESGSFTIRVGAYPDTHPEAPHAQADIDWLKAKLDAGADEALTQFFFEAETFLR
FRDACAKAGIDKPIVPGILPIENWAGAKKFAKRCGAQVPDWVDQAFDKAIRDNRHDLLAT
ALCTELCSDLIDEGVDKLHFYTLNRPELTRDVCFALGITPKADLQNVA
>A0A1G9HRC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. ok362|TrEMBL
MSPPSLIDTHPNLAGAAPVALSYELFPPRSPAAAESLWTTIGELEATDPDYVSVTYGSNG
SNRSTAVELINRLVQETTLRPLAHLTCVGNSPQELAEIIGDLLDVGVRGILALRGDQPKD
GATPPPGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLLTRARRAGVTIPIIPGVMPLTSLRRLARLGELTGVE
PAPELIERLAAADTDAERTRIGVSATVDLANAALAAGAPGIHLYTFNEHAAALDVLDKLA
LPRPRSSNRQGGNRHGAGRIDASRRAASGQLAS
>A0A1G9IPD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. ok362|TrEMBL
MFPTRLEIIPSEGIVEKIQATVPLTTTLTITCLPHHGIERTMRTAVQLSVLGYSVIPHLA
ARSLHDRGQLTGIIRDCDVASIGEVFVVGGDRKQPAGPYDSALPVLEDIAQYSGGMMRTG
IAGYPEGHPSVGPVDLLDALLAKQHLASHVVTQMCFSAPAILDYAALLRREGMRLPVWAG
VAGSVPRTKLVSLASQIGVGSSLKFLSRKGPLARKLLSGDRYSPQTLVSGLESRPGNIAG
IHLYSFNGLDSIPGGPGQASTPAALQPELI
>M7BWD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chelonia mydas|TrEMBL
MVNEAHSASSRSEGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRYDSGDKWFSLEF
FPPRTANGAVNLISRFDRMGMGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLET
VLHMTCCNQTKEEITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVEGFNYAVDLVKHIRC
EFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVSAGADFIITQLFFRSETFLAFMKDCQ
AIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKEVIEPIKDNDAAIRNYGVELAAS
MCRELLDSGMVSGLHFYTLNREVATTEILKRLGIWKEDPRRPLPWAVSAHPKRRVEDVRP
IFWASRPKSYIHRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEE
LTSEESVFEVFTCYISREPNREGHKVTCLPWNDDPLAAETNLLKEQLDKVNRRGILTINS
QPNINGRPSTDPIVGWGPSGGYVFQKAYLEFFTSSENITALLKVLKMKKYELRVNYHIVN
VRGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEEE
SPSRMIIQYIHDNYYLVNLVDNEFPLENCLWQVVEDTFELLNCPTEQ
>U6S6W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis JCP8151A|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNAAGVFNHASDL
VSYIRSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A3D5KN18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagales bacterium|TrEMBL
VDMNRGKYLEEDSIQGYKTDFNIGVAGYPEKHFESPNLKSDLRHLKEKVDAGADYIVTQM
FFDNKKYFEFVELCRAADINIPILPGVKPITTKSQANILPTIFHIDLPEQLADEVEKCKD
NAAVREVGIEWAVAQSKELISKGVPSMHFYSMGKSDPIYRIAKELF
>A0A446ZHC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLRIVHQELQPLNPDFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIRQHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGVYIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLITGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A3N2MIG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Isolate-037|TrEMBL
MRIIDIINDSPNPVFSFEILPPLKGNSIYKVFDIVEKLKRFDPKFVNITSHHSEYIYKPL
PDGTHRRVSIVKRPGTVAIAAAIQNRYGLIPVPHIICKGFTKEETEYALLDLNFLGINNL
LVLRGDEKGQDSTMGQPNISHEHATDLQKQINLFNEGIGLEDMRIQGIETPFSYGMACYP
EKHEEAPNMESDIYYMKKKMENGADYFVTQMFFDNEKYFSFVERCRAAGINVPIIPGLKP
ISKMSHLTMLPKVFRIDIPEELASRIRECKTDTEVKQVGIEWGIRQSRELLEKGALGLHY
YTMSVSDSVSKIVENVY
>A0A225AJN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces atroroseus|TrEMBL
MHVGQRLQDQAASGRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRS
DLTCEMVRIAQTVFGLETVMHLTCTDMPREKVDAALEAAYNAGCTNILALRGDPPREHEK
WEAAEGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSSF
IVTQMFYDVDNFLDWVQKCRAKGVNVPIIPGIMPISTYDAFIRRSKWTKIRVPPQWLEEL
EPVKADDARVRELGTKFVSELCRKLLKSGEIHHLHFYTMNLAQATRLILEELNLCPSEAA
PLHKPLPWRKSLGLRRRSEDVRPIFWRNRNHSYIARTADWDEYPNGRWTDARSPAFGELN
AYGVRLKGTSQQNVKLWGTPKSLKDLADIFVNYLNGKLERLPWSDTSVTSETSGIETELI
ELNKRGFLTINSQPAVNGVKSTDPVHGWGPRNGYVYQKAYLELFIPPEHVDELLRRIEKN
PDLTYYCVNKTGELKARSDDGPNAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQLGDDW
AKCHPADSPSRKLIQRMMDEWYILNIVNNDFHKKDDIFRLFDGLVIKDLATETPADSTTD
>A0A6I3KE96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium album|TrEMBL
MAVGSERKSRLLGADEIDVSFEFFPPKTEKMEEALWSCIERLAPLNPEFVSVTYGAGGST
RERTHNTVVRLVNETKLKPAAHLTCVAASKAEIDAVAQDYWNEGIRHIVALRGDPVGGPG
TSYHPQADGYINAADLVGGLKRIAPFEVSVAGYPEKHPESPTFAADMDNLKAKVDAGADR
IITQFSFDNTHYLRFLERARAAGIWVPITPGIVPIHNFKQVAGFAARTGASMPSWLARRF
DGLEDDPATSHLVAAAVATEQAMDLVDEGVKKFHFYTLNRADLVYAICHLLGLRPHPQTQ
PVSAAVKPAKARATG
>A0A7Y9ATS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineococcus aurantiacus|TrEMBL
MTLAPLVAGAAGRPTLSFELFPPRSETGRDSLWRRLSDLLGSNPDFVSVTFGAAGATRGP
SRDLLAHVLTTSAVPAMAHLTCVGSSRRQVVELATEFLDAGVRNVLALRGDPPAGVPDWT
PHPDGVATARDLVELLQVADRRRLALRGGSRPLDEGPLSLAVAAFPRARDHHELAVLRAK
QDAGARFAICQVTFSAQEYAAFVRRARAAGITIPLLPGVAVSDDPRRLERIGELTGVRAP
RGLLAALDTDDAPTRRRAATAFTSGLAHGLLEAGAPGLHLYTFNAAAPALDLLDHLDLTR
PATHPRPAAAVEATAAAGGSTR
>A0A7Y2R5U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium laguerreae|TrEMBL
MALKNEARGRNDIRVSFEFFPPKSEEMEGQLWHAVGQLQEWDPDFVSVTYGAGGTTKAPT
LSTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQ
PHPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQ
FFFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFD
DKPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRPAAKSAGAA
A
>A0A430LUD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium euwallaceae|TrEMBL
MHIKEMLTDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRDQDK
WTAADGGFQYARDLVKHIRSTYGNHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKKVRERGVNVPILPGIMPIATYASFLRRANHMKAKVPQAWLDAL
EPVKNDDVAVRDIGKSLVAEMCRKLLANGIHHLHFYTMNLAQATRMVLEELNWAPSAERP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTVQDIAQLFVRYLRNEIDSLPWSESPLTSEADEIRDDLVE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPSNGYVYQKSYLELLVHPDVFNDMIGRIEGHP
DLTFYAVTKDGELRSNAPSDCPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDASSPSRALIDEVMNEWYLVNIVNNDFHQNATIFELLKGLEVKDLTTPATPKSEPE
ANGTEPLANGAAAA
>W8I8N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer adhaerens OV14|TrEMBL
MTAQTLYPAERGNLRLSFEYFPPKTDEMEAQLFQTAEDLSVFCPAFVTVTYGAGGSTKAR
SLTTVRRMIEEKGFANTAAHLTCVGAPKAEVDTVIDEFLAFGVRHFVALRGDPQGGIGST
YQPFPGGYESSSDLVRALRDRGDVEISVSSYPEKHPESPDVAADIDMLKRKVDAGATRAL
TQFFFDNDDFERYLERVRRTGIEIPIVPGILPINNLGQVQKFAGLCGASVPEVIVTRLSH
LEGQPAERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFERADEASRG
EDISLKAFAGAAA
>A0A1W1YA19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulophaga tyrosinoxydans|TrEMBL
MERAGGEATMKVTDHIKNAKGNTLFSFEIVPPVKGNSIQELYDNIHPLMEFNPPFIDVTT
SREEYVYIDKAGLYDKKITRMRPGTVGICASIKHKFNVDTIPHVICGGFTKAETEYMLID
CHYLGIDNVMALRGDAMKEEKYFTPTEGGNVYATDLVSQIQNLNKGKYLHDDVQGEDRSD
FCIGVAGYPEKHLEAPSFMSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEAAKAIGIQ
VPIIPGIKPIAVKRHLQLLPQVFSLDLPQDLVEAVEACKNNLEVRQVGVEWAIQQSKELK
AAGVPVLHYYTMGKSDNIKAIAKEVF
>A0A4P6DUM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pullorum subsp. gallinarum|TrEMBL
MSKPLFSLEVFPPKRTAPIGTIYDTLDGLHGVDPAFISVTYGTGKQSDRTITARIANTIR
TEYGIPAVAHLTAQYLDRDQADEALDMFAQAKVAAVLALRGDRNPEREPAGVFMHASDLT
RYIRQTHPEMTVYGACYPECHPQSRDLDEDISWLKVKVDAGASHLISQLFYDNADYLRFL
DKARAAGIDVPIEAGIMPVTNAASVRRMTGMCSSKVPERLATILDRWGDDPNTLKEAGII
YASEQIADLVARGVDGIHLYTMNHPGVTRRIWQNVQGLF
>A0A0B7N7V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasitella parasitica|TrEMBL
MKVVDKINKAENEGRTYWSFEYFPPKTEMGVQNLYDRMERMQRFGPEFVDVTWGAGGTSA
DLTMDIVATSQSVYGLETMMHLTCTNMPAAKACGCQNILALRGDPPKGQLNWESCENGFN
HAADLVRYIRKNYGDYFCIAVAGHPEGHIDNPDKEDDLLRLKEKVDSGADLIVTQLFFDV
DVFVRFVERCRAIGITCPILPGIFPIQSHAGLKRVISFNNNAVPQKLWDDLESIKDDDQA
VKDYGIDLAVDFVNQIREKTGINGFHIYTFNLERSSRIILEKLGLVPEQEHVKPLPWNPS
LGPNRTKETVRPIFWKNRAQSYIQRTESWDEFPNGRWGDARSPAFGEFDRWGVSIKYPVK
KRLDMWGEPQSPDDIALLFAKYCKGRLEGLPWSAQKLEPETDTIKQRLAAINLLGYLTIN
SQPAVNGAKSNHPVYGWGPKNGYVYQKAYIEFFIPPSKLGELVNKIGLDSEVTYFAVNKK
GDLKTNTVDDEPNAVTWGVFPGKEIVQPTIVEPIAFMAWKDEAFGLWYEWAHTYDRQSLA
AEVILDIYENWYLVNIVHNDFQDENGIWRLFDLEIDGDLSKKLRRGSGSL
>A0A3D3K3Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp|TrEMBL
MNVLDTIHSALAQRKTRFAFELLPPLKGDGMGGICAAIDPLMEFDPAYINVTFHREGIKQ
TQRADGTAEWHVVRRRPGTVGISAAIRSKYGVETVPHLICGGLSRYDIEDALIDMDFLGL
HNVLALRGDKSQNEKRFMPHPQGHAHAVDLVRQIAAMNRGQFVDGEVEECHHSRFSIGVA
GYPEGHDEATSPEADIAALKAKVDAGAEYVVTQLFYDNARFFDFTARCRAAGIGVPIIPG
IKPLSTVRHLSLLPDTFGCSIPEPLRREVLAHGDDPTAVRQIGTEWAIAQSRELMRVGVP
VLHYYPMGKADNIIRIARELF
>A0A538SG02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium|TrEMBL
MLGAHALGIRNILCLTGDPPSLGDYPNATAVFDTDAPGLMRIVHKMNRGTDLAGTSIGAA
TQFAVGCGVNPTAEDLDGEFEYVKRKLDSGPQFVMTQPVYDLDCWKRFVERLSTLTTIPI
LIGVLPLQSYRHAEFLHNEVPGIQVPDAIRARMRAAGNEGQRVGVDLARDLLAECRTMAS
GVYLMPSFGRYENCLDVLEGAL
>A0A1H4SZA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PAN_FS17|TrEMBL
MTTTLREVLARDLAAGTPTFSFEFFAPKTESGTRGLWDAVRRIEPLSPTFVSVTYGAGGS
SKDRTVEVTRRLATHTTLRPVAHLTAVDHSVAELRHIIGQYADAGVRDVLVLRGDPPGDP
NGPWTAHPEGFTHAHELVALVRDISDFSIGVAAFPERHPRSPDWESDIRHFVAKCRAGAD
YAITQMFFDAEDYLRLRDRVTAAGCTTPIIPEIMPATDVRQIRRFARLSNASFPADLAQR
LEAARDDPAEGHRIGVAHATHMATRLLTEGAPGLHYITLNRSPATYEIHRNLGLTGRGVR
VAA
>A0A250FXN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga stomatis|TrEMBL
MKVTEHIAKAKGKTLFSFEIVPPKKGNNIEELYRNIEPLIEFKPPFIDVTTSREEYFYKE
HPNGLLEKKITRMRPGTVGICSAIKYKYGIDTVPHVLCGGFTKEETEYLLVDCFYLGINN
VMALRGDAMKEERYFQPTKNGHTYAMELVKQIKDLSKGKYLHDVIETDYGADFCIGVAGY
PEKHIEAPSMSFDLARLKEKVNAGADYIVTQMFFDNQKYFDFVEKVRLAGIDVPIIPGIK
PITTKRHISLLPQVFKLDLPEELVSELEKCKTNSEVKQVGIEWAIHQSKELKNYGVPTLH
YYSMGKSDGIVDIVSKVF
>A0A828RQF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis M01-240013|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A7G5NWP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium butyricum|TrEMBL
MIKEFLNNNILICDGAMGTYYSEKTGNDISYCEFGNLNDKNTIRRIHEEYIEAGAKLIRT
NTFSANSKELGVSRKTLKDIIESGIEIAKEAVYNKEVFIGASIGPIRENGADENVVEVLE
EYKFIVDCFLDNNINVFIFETLSNLDYLEEVSTYIKNKKPESFILTQFAVKPDGFTRDGY
SVSKIVGEVKKINTIDSYGFNCGSGPTHALELIKKIDIGDDIVSSLPNAGFPEIIHERTV
YPNNPVYFARKVKEIKKLGVSIIGGCCGTNPSYISKLRDTIDNKPEAGDKIKRYEHETYN
EKNIIKNKFKEKVKNGDFVIAVELSAPVDTDINKIMTGAKVCKDNNIDIVTVPDSPMSKV
RADSVVMSSKIKREIGIEAMPHMCCRDKNTNAIRSSLIGGHIEEIRNILAITGDPISDAS
RIETKSVFNLNSFKLIELINDMNNEVFTSDDIFIGGALNLNVLNKEVEYGRMMKKVERGA
KFFLTQPIYDDSAVEFLKSIKERTDVKILGGILPVVSYRNAMFLNNELPGVTIPQEILNR
FSEDMNREEGQNIGIDIAVSMGKKLKGICDGLYFITPFGRVNMIVDIVNRIKEV
>A0A8C8YXF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prolemur simus|TrEMBL
MDHRKAKVLPAVHHCPSLGMRASEAGSMRFSVPPSISRNPAMVNEARGSGGLNPHSEGSS
SGSENSKDSSRCSTPGLDPERHEKLREKMRRRIESGDKWFSLEFFPPRTAQGAVNLISRF
DRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQEEITG
HLHKAKQLGLKNILALRGDPTGDHWTEEEGGFNYAVDLVKHIRNEFGDYFDICVAGYPKG
HPEAESLEADLQYLKEKVSAGADFIITQLFFETDTFLHFVKACTDMGVTCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHF
YTLNREMATTEVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPRSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVHYLS
GEPNQNGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYDEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDALELLNRPTQSQREAEAP
>A0A818UC40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sordida|TrEMBL
MEFTVSDNQAVPNNHKINGVETHLQSTCDLNGFKRIESEGANISAKGCCLQPIKYVSLKE
KILKRIADHDRWYSLEFFPPRTPSGAANLIGCFDRIAAGQPLFCDITWHPAGDPASNKET
SSMMIANTMLNYCGIDTMLHITCYGAKKANMLEYLYKAKDCGIRNLLALRGDPLVGEEWD
AEKSDFRYAVDLVKFIRQHFGDYFVICVAGYPQGHPDSTSYEDDLSYLKKKVDCGADFII
TQLFFQPETFLKFESDCRAIGITCPIIPGILPIQGFASLRNIVRLAKLDVPKEILACIEP
IKDNDEAIRNFGVQTCLDLCRTLLESGKVDGLHFYTLNREFATIEILKKLGLWLEEQTLR
ALPWKKTSFSHARSKENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGALTDYH
LFYMKIDATRDELLDEWGRELTCEQDVWNMFACYVGGEKNCLNKVVRHFPWTDDELALET
GLIRKELVEFNSQGILTINSQPAVNGKPSLDPVVGWGTPNGYVYQKAYLEFFTNEGNIPA
LRAVLKKFPGVNYHFVNKSGEISETNADDEQPIAVTWGVFAGREIIQPTVVDPVSFMIWK
DEAFSLWTERWGKLYEQESCSRAIIDKIANTYFLVNLVDNDYPQGSCLWQILDSMFEYQK
LSNKHIDS
>T0IA74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. UNSWDHB|TrEMBL
MPGIMPVYSIKMMEMLAGNCGAKIPEKLKKGISELPEGDTKALVDFGIEYAMGQCEELLK
EGVRGLHFYTMDKSESAVGIVKGLRSKSFLTVK
>A0A718XFR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium (strain SL1344)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAE
>A0A814GGC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sordida|TrEMBL
MEFTVSDNQAVPNNHKINGVETHLQSTCDLNGFKRIESEGANISAKGCCLQPIKYVSLKE
KILKRIADHDRWYSLEFFPPRTPSGAANLIGCFDRIAAGQPLFCDITWHPAGDPASNKET
SSMMIANTMLNYCGIDTMLHITCYGAKKANMLEYLYKAKDCGIRNLLALRGDPLVGEEWD
AEKSDFRYAVDLVKFIRQHFGDYFVICVAGYPQGHPDSTSYEDDLSYLKKKVDCGADFII
TQLFFQPETFLKFESDCRAIGITCPIIPGILPIQGFASLRNIVRLAMKIFIKDVFLQKLD
VPKEILACIEPIKDNDEAIRNFGVQTCLDLCRTLLESGKVDGLHFYTLNREFATIEILKK
LGLWLEEQTLRALPWKKTSFSHARSKENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSS
APSFGALTDYHLFYMKIDATRDELLDEWGRELTCEQDVWNMFACYVGGEKNSLNKVVRHF
PWTDDELALETGLIRKELVEFNSQGILTINSQPAVNGKPSLDPVVGWGTPNGYVYQKAYL
EFFTNEGNIPALRAVLKKFPGVNYHFVNKSGEISETNADDEQPIAVTWGVFAGREIIQPT
VVDPVSFMIWKDEAFSLWTERWGKLYEQESCSRAIIDKIANTYFLVNLVDNDYPQGSCLW
QILDSMFEYQKLSNKHIDS
>A0A5P8K042|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces phaeolivaceus|TrEMBL
MALGTASTRTDRARTVRDMLATGRTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSV
TYGAGGSTRAGTVKATEQIVADTTLTPVAHLTAVSHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMAEWVAHPQGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSPDWDSDVARFVD
KCRAGADYAITQMFFHPESYLRLRDAVAKAGCETPVIPEVMPVTSVKMLERLPQLSNAAI
PPALKERIVTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
PHHSPRA
>A0A328WGP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus lautus|TrEMBL
MKPNLRQAWENQVLVGDGAMGTYLYQKGFPVGISYEELNLTSPEVIGNVHRQYVEAGAQV
IETNTFSANHDKLSKYGLEAKVGEINRAGVRIAREAAGDNGYVVGAVGSIRAGKRSNIST
SELKRYFEEQLSVLISEGVDGILLETFYDVDEIQLALAQARMLSDLPVICQFAVEDIART
LDGFTMPDAYRILSQEGADVIGFNCRTGPNGIMRALETLNGIMNLPASVYPNAGIADYVD
GEYRYGASPEYFGKTALEFADRGARIVGGCCGTTPEHIAEISSALSGYVPAPLPIVEEAE
VNRIVIHETAQEQFYERSGEPTIVDIVKERHTVIVELDPPRDLDITKFMKGAEALKKAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVVGAAFNP
NVRHLDKAVARLEKKIASGADYVMTQPVYDPELMVRLREATAHLDIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAMGVKIGKELLDVATEHFNGIYLMTPFMFY
EMSVQLMEYVWEKSGRRLTPLFH
>A0A0U3J7X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum dicentrarchi|TrEMBL
MKVTKHIEKANGKTLFSFEIIPPKKGNNIQDLYQNIEPLMEFNPPFIDVTTSREEHLYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFSKEETEYLLVDCHYLGIEN
VMALRGDAMSHQRYFEVSKGGHQYATQLVAQIKNLNKGKYLHDVIEANHKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVKHAREMGITVPIIPGIK
PISVKRHLQLLPQVFKIDLPQNLITEIELCKNNQQVRELGIAWAIAQSQELLKSGVPVLH
YYSMGKSDNIKAISKALF
>A0A2C5ZYZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cordyceps sp. RAO-2017|TrEMBL
MDKITDKIAALPDGAEYFSLEFFPPKTSMGFSNLRHRLERMEQALRPLFVNVTWGAGGST
AIKSLELAELCQRELGLTTCLHLTCTNMSRRLLDKALEDAKVLGIRNILALRGDPPRMDE
YRDPQDTDDDSDEFTWAIDLVRYIRRNHGNHFCIGVAAYPEGHADGSFPLNQSLEHDLPY
LVEKVQAGADFIMTQLFFDIAAYENFDKKLRAHPSGAFKTIPIIPGLMPIQSYQMIKRTC
KLSHARMPEPILARLDSVRGDDEKVKMVGVDVISEMVNQIRAIKSERRPSHKGFHFYTLN
LEKAVSLIVEKTGLIQQDAAEGDDAVVVDDLLPSPPPLLQVNGNGLLRPHSHSRSSRRHS
SVGSDPHNRVIVDNRPVAHPEWEATGEEAAIPAASINSRANTLAISEGEGVLGREATWDD
FPNGRFGDARSPAYGEIDGYGVSLHVSITQAVRLWGHPQTREDINDIFVRHVRGELSAIP
WSEEGLTAESSAIQPRLVELNGKGWWTVASQPAVNGAPSSDRTFGWGPALGFVFQKSFVE
FFLPSADWKQLLEKLRQPEVGALVCFYAANARKDFESSDRSGGASGAGTASSTNAVTWGV
FPGKEIVTPTIIEEVSFRAWAEEAFGIWGEWAKVYGRGSESEKLLKSVKDDYWLVNVIHH
EFVDRDALWRLLLE
>A0A3D3E101|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillales bacterium|TrEMBL
MTKISFEFFPTQTEAGTEKLLKVRDRLAQENPEFISVTYGAGGSTRDRTRSIVHSIQESG
IAAAPHLSCVGDSKADLREILIDYKNMGINRIVTLRGDLPSGAGMANSELRYANELVEFI
RQETGDHFTLEVAAYPEMHPQATSFEDDLKNFERKVKAGADSAITQYFFNPDSYFHFVDR
VQAMGIEIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSESIMKFGEEVV
SSLSQKLLDQGAPGIHFYTMNQAEPSLAIWNNIK
>A0A067QLK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zootermopsis nevadensis|TrEMBL
QVDVGASFIITQFFFQVDVFINFVQRCRRIGIRVPIIPGVMLIRDYTSLIHTSNICSVKV
PREVLDIIEPIKDNEEAVRKFGVHLAVEMVSYLFRHNYSYGAHFFTLNR
>A0A1V5CXU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdus sp. PtaU1.Bin153|TrEMBL
MTEKKKESSCNTPGDELKDTLYLKYSYSRDSANHNAKLDIGKTTAFKFPGMHTGVLTLYT
EKTGWMPHKYGKFTEYAYTCFRMSTERGILQDRNFWQVWPDKTLKNHFREIIEKGEHFVY
TVELVPGRGSKGKTHDDVLDLASKASRGGLIHAMSITDNPGGHPALTPSVLGVEIARMGI
DPIVHFTCKDKNRNEIESILYGMDRIGIRNLLAMTGDFPLYGFEGKTKPVFDLDSVQLLH
LITTMNRGLQIDARAPGGGRILPPTRSFKGCAVSPFKQLESETLAQYFKLWKKIRAGADF
VITQVGFDARKFDELLRYMRHLDIKVPVLGNVYILNFPVARVMNRKAVPGCVVTDRLCRA
YEEESRAPDKGKTARLMRAAKLIAVLRGIGYNGVHIGGPNLKYEDIEWVIGKSADLSDKW
QSLVPEFDYPQPDGFYLYERDNETGLNTDVFSGQRSNPRKSSGYALMRFFHHLVFAADAP
LYNSACSFFSKMSGTRLERVLTELEYWIKFVSSGCRRCGDCTLAEIAFLCPQSQCPKFLL
NGQCGGSSEGWCEVFPGKRRCIFVRAYDRLKAFGEEESLKGEYIRPRHWELDQTSSWANY
FLGRDHHVEKCNGDAP
>A0A142M5F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter aminovorans|TrEMBL
MKLSVTRSDLDETIGGLVGNFSIEALPKDTQKLDDLRNHLPAGTRVYVAYTSGSTSEIVE
AAEKLRHHGMEPVPHIPARRFSSHDELRDFLGKLAARAAVKQVLLVGGDTTRPEGPYAAS
LDVLKTGMLEGHGIEAVGLAGHPEGHPSVSRDALRGALIDKCDYATKAGLEVSLVTQFLF
DTDKLFAWHADFVEQTAPGIPVDVGLPGLAKMTTLMRFAKDCGVGASLGMLTRHAGRAFK
LATSFSPEATLVDLAGGVRAAGRPLFRSVHFYPFGSFERTAEWLRGLQSQGPTRSKKHLA
EAL
>A0A1Q8W8S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MHDNEPTGPTAAAGGRAGGLSSAETGTARRLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPADGISSGGHEGSARESEAGRCEAAPRVRAVQEQTNPSECVLAH
VLESSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRADDVAGELRH
ADDLVRVIREVEADFFGDGRRHVTIAVAAYPATSDHIEAIEVLAAKQAAGADMAITQVFY
DAADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSTLGSASGAT
LVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDA
VDRGYLQATPGRGPSFLRRGSPGAALSSRHPVQPHTTITKENA
>A0A142M5T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter aminovorans|TrEMBL
MNQFPLSRRSDIGNKIRVSFEFFPPKNDDMEARLWETVTRLEPLRPQFVSVTYGAGGSTR
ERTARTVKRILEESTLTPAAHMTCVDATREEVDQVIAEFAAMGVKRFVALRGDPKEGVGA
AYQPHPGGYANGAELVGALKAQGDFDISVSAYPEKHPESPDFVTDFDMLKRKVDNGATRA
VTQFFFDNDLYERYVERARKAGIYIPIVPGVLPIHSFTQVANFASRCGAHVPGWLAERFE
GLDKDPQTHALVASAVAVEQVLDLVERGVNDFHFYTMNRADLVVAVCHMIGIRPQPVVQG
SAAA
>A0A1I6R9B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. BC26|TrEMBL
MKPDLREALQARILTGDGAMGTYLYGMGFPVGVSYEEFNVLRPEVIADVHRRYYEAGARV
IETNTFSANLASLSHYGLDHEVEAINRAGVQIARDAVGNDAYVVGAVGSIRAGKRKNIAT
TQLEQLFHQQMDALLNAGVDGILLETFYDLEEALLALRIARKLSDVPVITQFAVEKEAVT
QDGHPLAIAFNNLKQEGADVVGFNCRSGPNGIMRAIDSIVGDIVLPLSVFPNAGIPDYVD
GKYMFSATPEYFAQSARKFADRGARIIGGCCGTTPEHIAAIAKSLEGYTPQTVQPEAQQL
PVQRERITLQSEQSVSEPTIVDLVKERHTVIVELDPPRDLNIQKFMDGARALKEIKADAV
TMADNSLAVTRMSNIALASLVQHQVGIRPLVHIACRDRNLIGTQSHMMGLDALGIDHVLA
VTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGIAFSGKALKQKANFITGAAFNPNVK
YLDKAIARLEKKIDSGADYIMTQPVYDNELIVRIAEATKHLSVPIFIGIMPLASGRNAEY
LHNEVPGIQLSDDVRRRMAGLEGEEGRAEGVRIAEELLDTALEYFKGIYLITPFMFYEMT
VQLTDYVWRKTSGKTG
>A0A8J6TQI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfatibia vada|TrEMBL
MKVKTPSKLEKILAAGHLAVTSECGPPRGSDMEKISEKAELIKDYVDAINITDNQTSVTR
MCSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAAAFDIHNILCLSGDHQSFGDCA
QGQNVHDLDSMQLAQTVRLMRDEAKFLGGGDISRPPQMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNMEKFELWLQIAGDRGLLDNVYILAGVTPFKSAGMAKYMKNRVPG
IEVPDELVKRMSDTPKEKQPEEGVKICIEQIQHLKEIKGVHGFHVMAIEWEEMVPEIVKA
CGLYPRPSVE
>A0A839HEW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiospirillum jenense|TrEMBL
MTTHYQPAFSFELFPPKTTEGMEQLKQTVARLNAVRPLYFSCTYGAGGSTRERTFETVTW
LREQGITTAPHLACIGSSEEEIRAIVQHYREQGVDRLVALRGDLPSGMGRLDSGTFRYAN
ELVTFLRREFSDEFYIEVAAYPEFHPQAPSAMADLENFKRKVDAGANAAITQYFYNADAY
FALLDSCAHLGINIPIIPGIMPITNYTQLARFSDACGAEIPRWIRRRLEYFGDDRDAIRA
FGHDVVLDLCERLLEHEAPGLHFYTMNQAAPGLRLWADLGLTGYRL
>A0A417DUU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM36-17|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVFKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNVLCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>S6FLE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis A12|TrEMBL
MTSNSKILSFEVFPSTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFRFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>A0A1S1EYU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC074C03|TrEMBL
MSSTMPLSPGRQVTIRQALSMPSAGSIPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFA
SVTYGAGGSSRDRTLRIAQRVSKQPLTTLVHLTLVEHTVDELREILRSYLSAGLTNLLVL
RGDPPGDPLGPWMETEGGLHYASELIELIKAESEFERFEIGIASFPEGHYRSPDLDHDTQ
YTLAKLRAGAEYSITQMFFDIEHYLRLRDRLAEADPVHGVKPIIPGLMPITSLRSVRRQV
ELSGAQLPSDLEERLIKAADGDEQANKDEIRKIGIEFSTNMAERLIAEGVPGLHFMTMNF
ARASQEVLHNLGMAPAWGTGQDMLRGGF
>A0A0Q5L4G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. Leaf160|TrEMBL
MSQRPASPPVSAALPVSFEFFPPKTAEGAEKLRAVRQQLYARQPEFCSVTYGAGGSTQEG
TFGTVREILSEGVSAASHFSCIGATEETVRAQLAQLKAMGVKRLVALRGDLPSGYGAGGA
FHYASDLVAFIRAETGDDFHIEVAAYPEVHPQARSPEADLQAFAAKVRAGADSAITQYFF
NADAYFRFVDETRRLGLDVPVVPGIMPILGSTQLMRFSDACGAEIPRWIRLRLLGFGDDV
ASIRAFGLDVVAELCEQLRTRGVPALHFYTMNQSGATLELCRRLGL
>A0A1V2HZZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia asymbiotica|TrEMBL
MGRASRGTSTNGFELICEIEPPTRPDLTHARHQIGVLAPVADAFLIPDNHLGRATVSSIA
VAHEVQAMGGRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVQGDKPTAGNRTGDLTV
RAMIEEVRAVADDPVYAGRPSFRVGTAAGLRPLPAWKRAADFVFVQVSYSVDALLRWRDT
HPIDRPVYAGVMVLASAGMARRLAATIPDIDIPTDLVERVERDQAAGVDAACEQILRLRD
SAAFTGVHLVPVSRYRQVAAQLEGLL
>S4H9Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis JCP7659|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNATGVFNHASDL
VSYIRSQRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A4P9ZDI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metschnikowia bicuspidata|TrEMBL
MALSPFFVSVTWGAGGSTAEKSLDLAGACQRELGVTSVLHLTRTNTKHSIIDDALSRGKA
ANIRNILALRGDLLRTQEYWTSDCDFQYAVDLVIGVAGYPDGHVYGADSSLQDAARDMPY
LEENVRAGADFILTQLFFGVEKFVAYESALRHDPYLCKTVIIPALMPIATYKVFVCATKL
SHAQGPADIQQRLSVPGYDDMVKAIGVDVLSDSFEQLRQRTDGHIRGFHFFTLNLETSVA
SIVERTGLLNASSKTLHVDHEDTVASDSGEDAPVRTRMHRTTLVDIKATWDDFPNSRFGD
SNSPAYEKVARTWGHPETLDDVNRVFLDYISGKFAVLPWTFLEFFVPKDMWDRQPRPRIK
DAFESRIVTYFCGDCSGRIVSNLDTHGGTHNSKSVEVLQFIIIDYQSFKAWNEAFLLWIE
WACCYKMGTKSYDLLNDIYCLHYLVSMIHHDFTDEGALWRMLLQ
>A0A2N9BGF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces chartreusis NRRL 3882|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSTDWDSDVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDRVSAAGCDTPIIPEVMPIASVRSLERIGSLTNAAF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHRPQA
>A0A847NQ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacteraceae bacterium|TrEMBL
MLSDKLKNGSVLLYGVTPPKLGTSDEKVEGIAARLKTRVPKELVDGFVIYDLQDESSRNS
NDRIFEFFDTIAPEVYHQNYLSEYEAVIYKVANKHTPDEFAKFIQSVNSPVVLVGSSSSK
EKVKFSLKDAYKIKNELAPNLTMGGICIPERHTAKGDENFRVARKSIDGCEFFITQAVYD
LESAKKFIDDYAKMEVEKKKIIFTLTPCGSAKMLNFMKWLGIYVGKEIEKTLLSSENMLE
TSVNLNIEMFKFLQIYSKNKGISIGVNVESISKRKVEIEASVELLKKIRENLK
>A0A4U8SCD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter trogontum|TrEMBL
MLESLVAKLRSNESFLSVEVSPRLSATIGQNVIDELESLEQADCFVCTDSPLARLKPSSI
LSSIKLQNALNKPLICTLSMRDRNSIALCGDILAANEFGLRAFLSLSGDSVKNGDCAGAK
GVFEESSLKLGRIIEDLNQGVAANGKALKDGVKPIYNFSVINSHANNTESLKKKMLKKLS
NSKVEGLFTQPVFSLQSAQFLLESLEEINENLEQKCVMILGFFPVLNYKVALFLRDKLPG
VYIPNEWVERLEKASIRSKEEEQKVGLELSRELFFGLQTLHNKFHFMSANKPSLLKEFVR
G
>A0A7X7DBZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MTQLPDFVPTDGGRHPSIVERIAASTTPRVPFSVEFYPPRDEAAEDRLWRAASVFSELGA
SFASVTYGAGGSTRDRTVRVVERIVRETDILPIAHLTAVGHTVDELREMIRLYGEAGVSN
ILALRGDPPGDPLGEWTAHPEGLHYAAELVRLIHEVGDFHVGVASFPEGHYRARDLDHDT
EVLVGKLRAGAEYSITQMFWDVDDYLRLRDRVVAADPEQGAKPIIPGLMPVTSLRVVRRM
VELSGCELPQGLSDKLRSAAGDGPEEDRSAVREVGIEFATGLCERLIAEGAPCLHFNTLN
FSRATHEVLANLSMVPSAGLSVGSN
>A0A0R2NM53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus fabifermentans DSM 21115|TrEMBL
MDLRTALKQRVLVADGAMGTLLYGNYGIASAFENLNLTHPDTILRVHQSYINAGADVIQT
NTYAANRLKLARYDLQDQVTAINTAAVHLAVKARQAADHPVYILGTIGGLAGDTDQDIQR
ATPAEITASLTEQLTALLATGQLDGILLETYYDLPELLAALKVVKAHTTLPVITNVSMLA
PGVLRDGTTFADAIIQLAAAGADVVGTNCRLGPYYLAQSFENLAIPATVKLAVYPNSGLP
GTDQDGQVVYDGEPSYFEEYAERFRQLGLNLIGGCCGTTPLHTAALVRGLASRSVVPHVS
HGYHPAAPSLAPANGQHLFLQKVATQKTALVELDPPKDFATDKFFKGAQRLKAAGVDGIT
LSDNSLATVRIANATIAAQLKLSYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAV
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKQATDFRVAGAFNPNAYR
TTVSTKSIERKISYGCDYLITQPVFDLANVQALATALADNHLDIPVFVGVMPLVSKRNAE
FLHHEVHGIRLPRSVRDRMAQAELDGNERAVGIQIAKELIDGICEHFNGVHLVTPFNRFK
TIIELVNYVQQKNLTPTK
>A0A1F4AA14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_65_20|TrEMBL
MRHAGALAVLYRLFIRLAPRLRRSVEWLGPERLERVVAPAERTIKGFFFDCHMCGRCTLS
STGMACPMNCPKLHRNGPCGGVMADGGCELDPGMRCVWLEALDGAKRVVGRADLDPAQIQ
RPADQRLRGTSVWIGAIMARDTAAPESPSEGPAAPGQVREPGALERACRSGRFVVTAELS
PPDSADPQDLLRRAAPFRGQVDAVNVTDGAGGNCHMGSLAASALLAADGYEPVFQIACRD
RNRIAMQGDILGAAALGVRNLLAITGDGVENGDHPQARPVFDLDSVSLLEVARGLRDRGA
YASGRSIGARPGLFLGATINPFAPPFRERIANFEKKIAAGAQFVQTQYCFDPEMLEAFMQ
EVRARGIERRCHILVGVGPLASARTARWMLAHVPGVHIPAQLLHRLEQSADQRREGTMIC
VELIRAVRQMEGIAGVHVMAHRNESLVPEILRESGLAAERDAVPPRHGAT
>D7DXQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc azollae (strain 0708)|TrEMBL
MQDTHSTSALNNFRKAVEAGDFLVTAEVAPPKGGNVTHTIEMAATLKGRVHAVNITDGSR
AVLGMSSLAASVILLQHGIEPICQVACRDRNRIGIQADLMGAHALGIRNILALTGDPVKA
GDHREAKAVFDLEAVRLLQLIRKMNQGIDFNNKNLNDGALDLFAGAAVDPQSASWSGLET
RFEKKIEAGAQFFQSQLITDFERLEKFMDKIASGYNKPILAGIFLLKSAKNAQFINRMVP
GVNIPEHIIDRLAKAKQPLEEGMNIAAEQVQIARSLCQGVHLMAVKKEDAIAPILDLAGV
GKVS
>T1AQJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
FHFYTLNRAELTYAICHALGLRPDAQAPAAGRTRAAGDVK
>A0A2G6HHZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MVSISDLLTNSAKPLYSFEFFPPASAEAENQLFGAIEKLKPLSPDFVSVTYGANGSNRDR
TINITGRILTEAKLPTMAHLTCVSQSKDELLQTLQRYKDIGVRHILAIRGDMPGGPQVEW
QQHPSGLANATQLVELIKEFDPEMTVGVAAFPDIHPQKNDPELDVEILLAKAEAGASFAI
TQMFFTAQRYFELVDRLRKSGCELPIIPGIQPVTALKQIKRFAKFSGADLPVELVSRLEN
SESEEQLRANGVAAATELCQELLAGGAPGLHFFTLNRSRATREIYAQLISDS
>A0A1I0QVB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivirga pacifica|TrEMBL
MKVTDHIENAAGKTLFSFEILPPVKGESVQNIFDAIDPLMEFKPPFIDVTYHREEYMYKK
RENGLLEKVTTRKRPGTVGICAAIMNKYHVDAVPHIICGGFNKEETENALIDLDFLGVDN
VLVLRGDAIKSEGRFVPDPEGHSYASELLGQVLELNQGKYIHEEITRNKTNFCIGVAGYP
EKHFEAPSLKTDIKYLKKKVEMGAEYIVTQMFFDNDKYFEFVEKCRKNDINVPIIPGLKP
ITTLKHMSILPSIFHVDLPDDLVDALEKCKDNEGAREVGIEWAIQQSKELMERGAPVLHY
YTMSKSKVVRRIAEALF
>A0A0P7XZU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium HLUCCO18|TrEMBL
MTPPTVSFEFFPPKSLEASFRLWDTLGVLAPLDPQFVSVTYGAGGTTRALTHDAVKTIHK
NYGVSVAAHLTCVDATREETLEIAESYAEAGVTEIVALRGDPPRGQGRFTPHAQGFAGSV
ELVEALAKTGKFTLRVGAYPDPHPEAATMQDCVDHLKRKIDAGATSAITQFFFEAETFFR
FRDACAASGITAPVIPGILPINSWKGVRKFAEACGTVIPAWLDEAYDKAIRDDRERLLST
ALCTELCAELVDGGVDALHFYTLNTPDLTREVCAALGVAPRVELSEVA
>E6PN83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MNLSHLSFEFFPPKTPEGAVKLRAARQRLYVHKPEFCSVTFGAGGSTQDGTLHAVKEIAE
EGVAAAPHLSCVGASRDSVRALLQRYRAEGIRRIVALRGDLPSGYGLGGEFHHARDLVEF
IRTETGDWFHIEVAAYPEVHPQARSPQDDLRHFVEKMQAGANSAITQYFFNSDAYFRFAD
DALAAGVDAPIVPGVMPITNASQLLRFSEVCGAEVPRWVRLRLQSFGDDRASILAFGREV
VANLCNQLVSGGAPGLHIYTLNQAEPTLDLLADLGTR
>A0A7W3RJP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces murinus|TrEMBL
MTTFSFEFFPPKTPAGERRLWNAVRKVEALRPDFVSVTYGAGGSSRDRTVALTRRIAAET
TLRPAAHLTAVGHSVAELRHIIGSYADAGITDVLALRGDPPGDPQGPWTPHPRGFTHAYE
LVELLRSLGDFTIGVAAFPEGHPRSADPRSDLRHFVAKCRAGADYAITQMFFRVEDYLRL
RDRVAAAGCDIPIIPEIMPATDVRQIRRFAELSAATFPEDLAHRLEAARDDPAASHRIGV
EHAVAMADRLLTEGAPGLHYITLNRSTAALDIHRTIHTSRSLSVH
>A0A6A5VVZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amniculicola lignicola CBS 123094|TrEMBL
MEKVTDKIHALPEGANYYSLEFFPPKTSMGFANLTSRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRSLIDEALEQAKVLGIRNILALRGDAPRSEE
YRDEAQSLDEDSNKDFTWAIDLVRYIKRQYGEYFCVGVAAYPEGHSDESHPEHQDPGFDM
PYLVEKTKAGADFLMTQLFFDVQAFDRFEEMLRGHESGVFKTIPIIPGLMPIQSYQILRR
TTKLSHAKLPAGLLERLDAVKGDDELVKQVGVQILSEMVEHIKKRPSVARRGFHFYTLNL
EKAVSHILENTHLIPPTTIEEDAVIDVELTPGTLSPPSGDSKRRRLSSVNSGPRNRVVVS
RPSKSSNVSYEAPEDEAGIPKGPINTRANTLAISEGEGSLGREATWDDFPNGRWGDARSP
AFGEIDGYGPTLHVSTPQALKLWGYPVEVSDISTLFRKHISGELSAIPWSEQDLSPETST
ISKQLLALNSKGWWSVASQPAVNGVKSTDAVFGWGPRNGFVFQKPFVEFFIPSADFDILK
PRLIAHAQITFFAANSRGAFECSEGAEEGVNPVTWGTFAGKEIITPTIIEAVSFRSWSEE
AFSIWREWQRVYPGGGGSAKLLAGVREDVWLVNVIWGDFVEGGGLWEFLMIGQNYGLGNN
ETASDIKSSSSLRTLDQLELQFNKQNIMLGTTIDGMTNGTLKSATNGKTQTSTIPPRLFS
VSKTPSLGDFKTLVTESKPVHYPLAASVKSNVPIYDLPEYSTLTNERKSALQDEWYHILL
HGPGVFVTKNMYRDTSLLERVNSAYAAIIQEEKQGPGKKGDHFASSGENDRIWNSFSKHC
LQDPESFAEYYSNPYLPLISSAWLGPHHRLTAQVNVVKPGSKAQISHRDYHLGFQSTADC
ERFPQALQVASQFLTLQGAVAHSDMPVESGPTRLLPFSQKFEEGYMAYRIPEIQNYFLEK
FVRLPLAMGDGLFFNPALFHAAGQNDSKDIQRCANLLQISSAFGKPMENIDTLPLVERCW
DGLREKFDAEGLTDSVEALVGNLAEGYPFPTNLDRRVPETAGMAPESEVGLLVRALKHGL
SKEEVIQGLRNMKEDEKP
>A0A1C5V3C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Eubacterium sp|TrEMBL
MGLLDKIKDHILLMDGAMGTYYNQQYGTELEAEEANLVHPEEITAIHKAYIEAGAELIRT
NTFAVNHLMFPKREECKRAIHAAIACARQAVAESGREVEIAASIGPIRQTVTEDDENTIK
EYQFLINSMLAEGIRIFVFETMLELKWVQPLSEYCKSQCEESVVIVQFSLNPSGYTQYGF
GMKEIIDKLCQMETVDIFGFNCGVGAAHLRKLLEKQTFPKECILSVLPNAGYQQELRGRM
HYGDDPEYYAKQMERMIPLGINIAGGCCGTTPEHIAALKKVLGGQAPQPKEVVEENADGE
SVSNAAPTDFISKLERGEKVFVVELDAPFDAQMDKFSKGVYALKENGVDMITVSDSPLAR
SRADAALLAVYAKRLTDISVMPHVAMRDRNLIGLRSEILGVHANGIRDFLVITGDPVGPD
NRGKITGVFDVNSIRFMEYLQHMNEEIFPDQPVYYGGALNYAGNNIRAIVGRMRKKMEAG
CAYFLTQPIFSEEDVQRVIELKEMTGAKIICGLMPLVSYRNALFMKNEMPGIHVNDEILN
RYDPEMSREEAEDTAVALCLDIAEALRGAADGFYLMTPFHRVGLVNRIINAIKQGE
>A0A1Q2MJB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limihaloglobus sulfuriphilus|TrEMBL
MNRIFTQKLNKNGLLFGDGAMGTMLYSRGVFVNTCFEHLNVSRPELVRQVHEEYAATGVD
FVKSNTFGANRLKLSRYGLGEQTEQIVSAGVKLARESCRPDMMTAASIGPLGVDIGSYDK
ALRAKAAEVFAEQVKISADAGADVLLFETFSNCDELICAIEAASASCDLEIIAHMTINDS
TETDYGSRIDESMRCVCRYENVAAVGLNCSTGPAAMLESIELVRGAVNKPLSVQPNAGYP
RNVDGRTLYMCTPEYMAEYAKRFYEKGAQVIGGCCGTTPEHIAAIINAVRPIKKSVTYKQ
PAIKIPAELAERLEPAPLETKSQFGAKLAAGEKVISIEVSPPRGFELSALIEKAKLCKDR
GACTINIPDGPRASSRLSAMVTALMIEQQCGIETILHFCCRDRNIIGMQSDLLGIQATGL
RNMLIVTGDPPKLGDFPDATAVFDLDSIALIKVIRELNRGIDIAGKSLGRRLELVIGAGA
NPAAAEPEREIQRYRQKIDAGAEYFVTQPVFDDESLLRFLDAAGGSVPVIAGIWPFSSLK
NAEFMANEVPGVSVPERLLERMSKLKSREDAIKTGIDISREMISRIEDTVAGFAVSAPFG
NVNIALEAAGL
>A0A5R9KEQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter sediminis|TrEMBL
MTKVTEFIDQAAGNTLFSIEIIPPLKGQNINELLNSIEPLMEFKPPFVDVTYHREELIDR
VGPNGLIERIPIRKRPGTVGICARLMERFHVDAVPHVICGGFTKDETEDVLIDLHYLGID
NVLVLRGDPEKSAGVFKAKTGGHTYASELVKQVSNMNQGILLNAETEMSPTNFCIGVAGY
PEKHIDAASMDMDYEHLRKKVELGANYIVTQMFFDNKKYFQFVERCRAEGITVPIIPGLK
PIATKKQLTVLAQIFHLEFPEELVSEVEKCASDKEVRQVGIEWGIQQCKELIDYGVPVLH
FYTMGKSDNVAQIAKQVF
>A0A1C7Z9X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae|TrEMBL
MSLDRRYSFEFFPTKTDAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRALLTQYKDAGIKRIVALRGDLPSGMGMASGELRYASDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDIKNFVHKAQAGADSAITQYFFNADSYFY
FVERVRKLGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EQVITQMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A0F0LHR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium azadirachtae|TrEMBL
MSRTTPVANPIAARALVDDFSLEMTGKDVPGLQEARDTIPAGTKINVTFLGNEDLDMRVA
AAKAVRDLGFVPVPHISARRLRSRAQLEELLGRLQEVGATDHVFVVGGDPATPDGPYASA
FDVIYTGLLLDYGVREVSIAGYPEGHPDIADDELWRHLENKSAVLAEQGLDAVILSQFAF
DTDPVLAWIDQVRARGIASEIRVGTPGPAGVKRLLGFARRFGIGANAMIVKKYGFSLTNL
MGTAGPDAFVSDLSALLAADTETGAVKLHFYTFGGLLATSAWARDFVAARR
>A0A1C5PVK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Eubacterium sp|TrEMBL
MKIRELLRQEQTSLSFEVFPPKKDTDFANVETATLGIAKLQPSYMSVTYGAGGSTKGNTI
QLASEIQQKYNVPAISHLTCVCASKENIKAALNEMKSAGIENILALRGDLPNNFEGEVFT
DFAHASELVTFIKENGDFCVGGACYPEVHPDSPTKADDLEGLKRKVEAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIIPGIMPITRRAQVKNAVKLSGCNVPERFKNIVDRFGDNEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEIAAGIQANLSEILKA
>A0A2X1UZQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oligella urethralis|TrEMBL
MNRIETEGSRFFSLEYFPPREQHARERLVETTKQLLEIDPAYISVTYGAGGSTREGTEDT
VQMVSNLGCEAVPHLACVGSQPEAIREILDSYQAKGIRRIVALRGDMPSGMGLADSPLRN
AVDLVRLIREHSGDWFSIKVAAYPEMHPQAESFDEDLDHFVAKVNAGANMAITQYFYNAD
AYWDFVDRAQAKGVTIPIVAGIMPITNYSKLARFSKMCGAEIPRWIAKRLESYGDDVQSI
RDFGHEVVSRLCDDLRRGGAPGIHFYTLNQAEPVLKICRALQAQ
>A0A158M0C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella holmesii CDC-H585-BH|TrEMBL
MTDTTSPAFSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTEDTVRT
LTNLGCDAAPHLSCIGASREQLREILNNYRQAGVRRVVALRGDLPSGMGGDAGELRYASE
LVRFIREETGDWFHIEVAAYPEIHPQAASPTVDLDHFVAKVQAGADAAITQYFFNADAYF
DFVDRAQARGVSIPIVPGIMPITNYSQLSRFSEMCGAELPRWIRLRLAEFGDDKASIRAF
GQDVVTELCQTLLDTGVPGLHFYTLNQSEAILGIWKNLQR
>A0A0X8JKY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio fairfieldensis|TrEMBL
MQIGTLIQAAKAPFFSLEFFPPSDEAQLPGFYATVEQLRALDPLFVSVTYGAGGARQHST
LAVTAELARRGFTTMAHLTCVGAEPGNIAAFLKELRAAGVGNVLALRGDPPKTGNWDWKQ
GYFQHAADLVAFTREHEPDMGIGVAAYPAPHPESRSFALDRRYTEEKLRAGADFAVSQLF
FDVREYEALVEDLRAKGLNVPVVPGILPIQSFDSLRRVLSLCGANIPGKLYLSLEEAHRK
GGAEAVRDAGLDFAVRQICQLLECGAPGIHLYTLNKGDLCLQIAEEVGM
>A0A7G8BN75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacterium sp. 4Y35|TrEMBL
MTNRLHNLFGNRTVIFDGAMGTMLYARGVFINRCYDELNLSQPELVRSIHEEYLQTGAEV
IETNTFGANQFRLVRYGLQDQVAKINQAGARIARQAVNQLKDKQAGMAWVAGSVGPLGIH
LEPLGKTSLEEARAAFAEQIQGLIAGGPGVGVDLLVIETMPALNEAEQALLAAREIAPDL
PVMALVTVDEEAHCLDGATPEVAAAKLASWGADAIGVNCSTGPATVLTAIECMAGASDLP
LAVMPNAGMPRAVDGRNIYLCSPEYMASFTRKFLKSGVQIIGGCCGTTPNHIRAMKSATR
AVEAQKSSAGHTARAPIVTETPPPPIDERSSLGRLIRDGKFVAMVEIVPPKGIDCSKELA
GASLLAGLGIDVINVPDSPRASARMSAQSLCIQIQQKTGIETILHYTCRDRNVLSIQSDL
LGASSIGLRNILCLTGDPPKLGNYPDATAVFDVDAIGLVNIVNRLNHGLDIGGNPIGAST
GFTIACAANPGVPDIDNEVRRFAYKVEAGAEYAITQPVFDLRVLEAFLKRIESFRIPVIA
GIWPLTSLRNAEFMKNDLRVAVPDTIMLRMQSAASPETARAEGIRIAQEMLETARPMVQG
VQVSAPFGRYTSAAEVLAAVLPNVTVTKQDITEGTSVVKL
>A0A1F9ZZ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon RBG_19FT_COMBO_56_21|TrEMBL
MMKAGSNLEKVFESGQFAVTAEIGPPQSANPAPLTHHAKMLKGYADAFNLTDNQTAVVRL
SSIASAVIIMREGVEPVIQMTCRDRNRIALQSDLLGAAALGVKNVLCLTGDHQTFGNEKG
AKNVFDFDSIVELQVFNQLRIQGKQVGGEVLKDPPKTYLGCAENPFATPYEFRAFRLAKK
VVAGADFCQTQAIFDMDMFEMWMDEVRARGLDKKIHILAGVIPMKSAGAARYMKNKVPGM
IVPDHIVDRMKGAKDAKEEGIKLCVEQIEHLKNVKGVHGVHIMAVAWEEMVPRIVEMAGL
LPRPNFES
>A0A150I2K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter venetianus|TrEMBL
MSKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIKRFVEKVQAGANAGITQFFFNPDAYFYFI
DRLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A3D6C877|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKTESRLEKVFAAGHIAVTSEVGPPRGCDVDIVEKKANMIKDHVDGINITDNQTAMVRMS
SIAGAVIVKNMGLDPIIQMVARDRNRLAMQADIIGAYSLGINTMLCLSGDHPKFGDHPTA
KAVYDVDSVNMIKMVTDMRDTGKFQGGADIKMPPKMFVGAAANPFADPFE
>A0A353H9N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKLKEALKKGRFVVTSEVQTPIDEDPQALIKRLEFVRGRVDGVTVPELEIEGVVGDSIKM
CDLLKKNRFESIYQTTTRDKNRPQLQKDLMLAHETGVENLLVFTEDYRITGDSLQEMMFF
HVDSGKLASVMEHMREGQTIDGKELPSKADFTLGSGVESGWGKNVPDLEMKEMEELTKIG
TGYFLTTPVFDVALFEKFLKQVNTFGVPVIAEVMIIRTAGMAQFLNRHFKSGLVPDWMIK
KLAGSPDKQRASIELFADTVKGLKDLCQGIHIITIGSEEKLRRYLDAAKLR
>A0A1B9HUA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kwoniella pini CBS 10737|TrEMBL
MPQLTSLLRDRITPFHTFEFFPPRTEAGLVNLLDRIQRLASAPLPSPLAVSVTWGAGGST
ADKSLELAEQVVKLGLEVILHLTCTNMPKEKVDQALERCKSLGVRNILALRGDAPRSEEY
STEPNPQPDYFQHADDLVRYIRNNYNDYFCIGVAGYPTPHPDSESSDKDLEYLKIKCDAG
ADFIITQLFYDVEGFLDWVRICREKGITQPIIPGIMPIQNFASFRRLVNLTKCPVPEAIS
SDLIPISSDDSAVKRYGAELATKMVKQVLESKLVPGIHFCTLNLEKSVRTILENLKWTST
SAPSIEKSPLVRHNRLIEDDQPQTNGTIAINGRTTVNGSGLGHQISELSVSPSEASQLAQ
WGLQHNSLPPVPKKGGIQGGATSNSGQGAEDSWDEYPNGRFTDVRSPAYGEIDGWGSGLK
ITAAQALKEWGTPTTVQELSAFFTSYLRSSPSTPTTPFCDLPLSPESLTILPHLLELNSE
KMQCWTVGSQPCVDAVKSEDPIHGWGPRGGYVFQKAFVEFFVKEEEVEKLKEKVELKSQG
KISFYAGNKKGKFKTNTEEDTVNAVTWGVFPGQEIVQSTIIETESFLAWKEEAFDIWTEW
SLLYPRNSISRKLLEKISSEWWLVSLIHHDYKDKEALWKFLIEE
>A0A512CZ72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrabacter aerolatus|TrEMBL
MVCGMAHGTASSMARAERFTRSIPAMIEADTPTFSFEFFPPKDDASEAQLWDAIRRLEKV
SPSFVSITYGAGGGTRGRTVRLTQRVLEETSLTPMAHLTCVGHSVAELRSIVGSYAAAGV
RNILALRGDPQGGLGQPWVAHPEGLDHADELVALVRGLGDFTVGVAAFPDGHPESSDISE
DAETLVRKEQAGAQFAITQMVFDVDHYLRLRDELARRGSRLPVVPAIMPITNARQVARMA
ELAGQPMPAAVTERLERHGDDADGVRAEGMAIATESSRRLLDEGAPGIHFITMNRSSATL
EVFGNL
>A0A139L2M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides ovatus|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDVEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A3A5AIY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKLKDALKRRKFTVTSEIQTPFDEDPLSLMKALEAVRERVDGFSVVETEINGVVGDSIKI
CKELQNNRFEAIYRTTIRDKSRPQLLKDLAQANKSGVENILTFTEFYRISGDSLQEMMFF
HVDSGKLQSVLEHMKEGRNVDGQELPSKADFLVGAGVDSKWGSEVPSMELKEMESMRDLG
AGFFLTTPIFEVDRFEKFMKHANQIGVPVIAEVMILKTAGMGSFMNRHVNPNMVPEHVIK
RLAKSTDRQKTSIEIFAEIVKGLKDLCQGVHIITIGAENKLKLYLDAAKLY
>A0A3A4SAJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKVAELYKNNAGKPVVSFEFFRAKTPKAAENLEKVLDLLAGTRHDYMSVTFGAGGSTREG
SYQLIDKLKSERNIKTVAYIAGVGLGPDDLTAVLDTFKRQGIETVFVIQGDEPQEDAAFT
PHPDALAHASDLLSFIKARYDFCLGAAGYPEGHIHAVSLEKDIEFAKLKQDCGAEYLVAQ
YFFDNRFFYDYVDRCRAIGVTIPIVPGIMPIYTVSLLEMLTSVCGSSIPDSVRKGLSDIP
ADDKEGVVKFGIDLATDQCRDLLKQGVPGLHFYTMNRGQSVHEIVTALEKEGLL
>A0A1K1LHJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio piger|TrEMBL
MQIAQALRQATRPFVSLEFFPPAEECHLPEFYKTVERLRSVDPLFLSVTYGAGGGKQQNT
LDVTAELARRGFTVMAHLTCVGAEPQAISDFVGKLRRAGVHNVLALRGDAPRGASGWDWN
AGHFHNARDLVHFLRSEHPDLGIAVAGYPAPHPDAATFASDRAYLADKLRAGADFVITQL
FFDVREYESLVSSLRAAGLEAPVIPGILPIQSFDSLRRVLSLCGANIPGKLYLELEAAHN
KGGVEAVREAGLRFAVRQIRQLLDCGAPGIHLYSLNKSEMCLRLVEEAGL
>A0A3N5V822|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MHLKSKFDKGVFAVLAEIEPPKGVDISSMLTNAKKVKGKIDAFVVPEMSSAVMRISSLGG
ALILKGNGFETIFQVNCRDRNRLALQADLLAAGASGIEYVMTVNGEDPRFGDHNEAKAVN
DIDLIELIKTISSMNNGKDMAGIELAGSPQFAIGSTVNAGASEQALVLELEEMKKKIDAG
ATFFITPPLFDPASIHPFLERSILSKTKIIPTVLLLKSVGMARYIDRHMDNIKIPAALID
RIQAAPDRVSECIKIASENIEMIRSEGFAGVLVSTIGWENRLPEILG
>H0TEC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. STM 3843|TrEMBL
MLAQTSVVSNRLSQMLPSASVEISSRGHQTGELSDNFAPGTGVSITFLPGDNYHHNIETA
AAVRRAGFNPIPHLAAREIHSRDALADFLARLRGEADTTSLLLIAGDVLAARGPFKASRD
IAESGLIERHGFISVNIAGHPEGHPFLDGNGALKLLVDWQDWSARSGIAVGVTTQFCFES
APILDWLRQLRTHGVSLPVTIGLAGPASPATLVKFALRCGVGNSLRAARNQIGRYGRLLT
DTGPDEVTHGLETAPPAETEAVIGFHLFPFGGLRKASRWLRDYENGATSVAAPLHQKP
>A0A7V8VKS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MDLADELQSRLVCGDGAVGTLLLEAGVPLDRCFEELCLSEPERIRSVHEQYVAAGARIIE
TNTFGGNAVRLERFGFEHRVAEINRAAAQLARDAATGKDVAVAGSVGPLGITADEAAARG
IDREQCFREQILGLLEGGVEWIFFETFMDFEEMALALRAKTELGDVPTICSFACSPEGRL
STGMPIVEAFAKLHENGAKILGVNCMNGPHGTVQLLERVPADYLLAAYPNAGYPKYHEGR
FLYHTAPEYFAQSAREMVAQGARLIGGCCGTNPTHIKAIAAAIGDLQPIRSKTVRVAVEP
LPSRNRTRELGVEESLLDRIAGKRRVIICELDPPKTLALEKFFAGAQALVKAGCDAITLA
DNSLAILRISNLAMGAMLKERYGITPLLHLSCRDRNVLGLQSELLGMAALGMRHVLPLTG
DPSRVGDHPGAASVYDVNSVELISIIKRLNEGFSQAGKSIKAATAFVIGCTFNPNARNLD
SQVNRLERKVAAGAQYAMTQPVFDLHLIEETKKRTQHLNIPIFVGVWPLMSGRQAEFLHN
EVPGIIVPDAVRAEMANAEGAEGRARGVRLAKKIVAATLAQYDGVYLITPFLRYDTTVEL
AEFARSL
>A0A838N4Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
LIGGCCGTNPTHIRAIAAAIADLQPVKSKTVRVIAEPLPLRRANNAEAVEESLLDRISNG
HRVIICELDPPKTLALEKFFTGAQALVKAGCDAITLADNSLAILRVSNLAMAAMLKERFG
ITPLLHLSCRDRNVLGLQSELLGMAALGMRHVLPLTGDPARVGDHPGAASVYDVNSVELI
SIIKRLNEGFSHAGKSIKSLTGFVIGCTFNPNARSLDSQINRLERKIAAGAEYVMTQPVF
DVRLLEEMKRLTVHFGVPIFTGVWPLLSGRQAEFLHNEVPGIVVPDAVRAVMAGSEGAEG
RARGVRLAKEITEAALQQFEGVYLITPFLRYETTVKLAEFARGL
>A0A8H4YB93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sp. NRRL 66182|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
AQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALADAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTQGDYFCIGVAAYPEGHAEESHPLGQSVEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGVFKTLPIIPGLMPIQSYQMIKRT
TKLSHAKIPQDILSRLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSYILERADLIPELPEDEEAVAPDDLPIPSLQINGSFNMRSSSHSRSRQSRRHSSV
GSDPHNRVIVGDRPAVHPEWEATGQEAGVRAEAVNTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQATKLWGNPKTREDINDLFVKHIQGELPAIPWS
EEELLAESSTIKPHLLQLNRKGWWTVASQPAVNGLRSSDDTFGWGPPSGFVFQKSFVEFF
IPANEWQTLKGKLTSPELRDSVCFYASNARGDYVSSDGSDHVNGTAASVAGTNPSTNAVT
WGVFPGKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLSGIKDEYWLVNL
IHHDFVDKDALWQVLSS
>A0A7J3UYL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanosuratincola petrocarbonis|TrEMBL
MREAFSRLISEIRSGKFVYTGEIAPGKTTRVETLIESAKALGRHVVACNVTDNPRARANM
SSLAASIAVQERAGVEAICQMTARDRNRIALTSDLLGASALGVRNVLVMSGDHPSLGDNP
SAMPVYDLDSAQMVELVRRMVDDGTDLAGNRIDGKVRIHVGVTGNPNADPLEVEIAKLER
KAQLGAEFIQTQAVFDIEVAERFLEAVDGFGIPVLIGILPCRSSRIAEQIAKNVPGIRVP
EEYLGMLRGAEDLNDQASVEERVDLMNEEYFSGMVSELRRTARLAGVHIMGVAYGRIVGR
IADGVERKMSCRVR
>A0A850JLI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. BRA 177|TrEMBL
MRRVRPDRPPTVRELLASGGRSFSFEFFPPKTDKGARNLWRTIRELESLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPDGVEYAAELVRMIRSYGDFCVGVAAFPYKHPRSPDVDSDVRYFIEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDVPILPGIMPVTQMSTIERSEQLSGAPFPPEV
RARFEAVADDPEAVRRLGVEHAAELCRELLDQDAPGIHFITFNKSTATREVYSLLGAGEY
GARGSVPPMTA
>A0A192F4V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. AntiMn-1|TrEMBL
MSQLIDKLKNNILVADGAIGTILYSEGLDTCPEAYNLTHPEKVAHIHRSYIEAGADIIQT
NTYGANFEKLKDFGLEHKVKEIHQSAVKIAKEVAKNDTFILGTVGGFRGVKQEDLGLSAI
QYHTEIQVDTLVESGVDGLLFETYYDLEELTNIIKATKRKHNIPIIAQLTALNTNYLRDG
TEINTALQQVAASGADIVGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSQF
KYSDNAEYFGNVAQKLINEGVRVIGGCCGTTPEHIEFIKSSIANLKPVTQKNVIPITKYT
STSSKSKQSQNLTSKVKQRPTIIVELDTPKHLDTDAFFRNIKKLDDANIDAVTLADNSLA
TVRISNVAAASIIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLLDINEILTITGDPSKI
GNLPGATNVYDVNSKGLTEIASRFNQGINTDGDALKTKTNFNIAGAFDPNVRKLEGAVKR
LEKKLESGMHYFITQPVYSTEKIKEVYEATRHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEEVLEQFEAVKDDKEKSKELSLKLSKELIDTVHEYFNGLYLITPFQKADYTLELAAY
SKSITSTKQEAIL
>A0A5K7Z4T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina widdelii|TrEMBL
MHLKNKFDVGKFTILAEMQPPKGVNVSAMVNSATRVKKAVDAFLVPEMGNAVMRMSALGG
AMMLQSKGMETIIQVNTRDRNRIALQADLLAAYACGIINVMGVSGEDPSLGDHHQAKAVN
DIDLMTLFNAVAKLQDGKDLAGNELSGAPSFLVGANLNARATGEELEKELARMAEKQAAG
VEFFIAPPVFDVEAMAAFMDKVDLKKTRVIPTVMLLKSVGMARYLDRHLNLTISHELIKR
MMRAPDKAVESLSIAAEIISEVKEAGFSGVMISAMGWEDKLQKLMDMI
>A0A838Q2C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MDLIDELQTRLICGDGAMGTLLLERGVPLERCLEELCLSEPDRIRTAHEQYAGAGARVIE
TNTFGANAVRLARFGLENQVGEINRAAAQLARTAMKGKDVAVAGSIGPLGISADEASARG
IDRAHCFREHITALLDGGAELIFFETFMDFEELALALRVKNEVSDALAICSFACAAEGRL
PTGTPIVEAFGKLQQSGAKILGVNCMNGPRAMVQLLERVPVDYLLAAYPNAGYPKYHEGR
FIYHTAPDYFAQAAREMVAQGARLVGGCCGTNPAHIRAIASAIADLQPVKSKTVRIATEP
LPSRSRAQELAGEESLLDRIGRGQRVIICELDPPKTLVLEKFFAGAQALVKAGCDAITLA
DNSLAILRVSNLAMGAMLKERFGITPLLHLSCRDRNVLGLQSELLGMAALGMRHVLPLTG
DPSRVGDHPGAASVYDVNSVELISIIKRLNEGFSHAGKSIKSATRFVVGCTYNPNARNPD
AQVSRLERKVAAGAQYAMTQPVFDVRLIKETKRRTAHLNIPIFVGVWPLLSGRQAEFLHN
EVPGIVVPDAVRAEMMGSEGAKGRARGVELAKEIVRAIFSEYGGVYLITPFLQYETTVEL
AEFARSL
>A0A4V5SPI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus terrae|TrEMBL
MKPDLRTVLDREIIVGDGAMGTFLYQLGFPVNTSYEELNITSPDVISDVHRQYVQAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
VELARNYDQQIDALLSEGVDGILCETFYSLDEVRIALRGVRKYSNIPVICQFAVDQVGRT
QDGFSVAEAFTVLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAASFVELGTRIIGGCCGTTPEHIAAISKALNGLQPPPLAPREVRT
DAPVIVAEPEQITRKGERGNGRNASEPNIVELVKERHTVIVELDPPRDLDITRFMQGAQA
LKAAGADALTLADNSLAVTRMSNMALGHLVSLETGLRPLIHIACRDRNLIGTQSHMMGFD
ALGIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVV
GAAFNPNVKHLDKAVQRLEKKIASGADYIMTQPVYDRELIIAMGEQTRHLEVPIFIGIMP
LASGRNAEYLHNEVPGIQLSDEVRARMSGLEGEEGRAMGVTIAKELLDTAMEHFNGIYLM
TPFMFYEMTAELTSYVWQKSGRVQAPLFRL
>A0A7S3HU88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Favella ehrenbergii|TrEMBL
RNLLALRGDPPRGATDWVAVENGFNYATDLVKFIREEYGDFFCICVAGYPEVHLQATSRE
DDIRHLKEKVDAGADFVITQLFFDNQIFYDWVRDCRLAGIECEIIPGIMPILGYDRFHRM
CKFTKTQVPAQIMARLEELKMDDQEVQAYGVEFGVEQTRDLIAHGHRFIHYYTMNLETSI
LKILLGNGTLDKQRSLPFQKMTYDGRTEEQVRPIFWAIKPKSYVAQTSTWDDFPNGRWGH
SSSAAFSLAA
>A0A2G6S4R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. 59|TrEMBL
MNAAHAQGTGFPVSFEFFPPKTPEGADKLRVARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILSEGVGAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLQAYVTKVQAGADSAITQYFYNSD
AYFRFVEDAHQLGADVPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A023X0N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacter radiotolerans|TrEMBL
MTGEALRREGRSAGGTSLLHALEHPRFEVVPLKGALSVADHLPPGAEVSVTCSPALGIEN
TLDFSEELLRRGFYVVPHLSARLVRDEAHLEGILGRLSEAGVREVFVVGGDAKEPRGPYP
GGLELLQAMRLLGHDFERIGVPAYPEGHPLVGEEVLTQALLAKQPFASYAVTQICFEPEP
ILLWLSRVRRAGLALPVYIGIPGVVDLKKLLGISLKIGIGASVGYLRKQHGWLGNLVLRG
RYSPESLVRELAPHAGEGGIEGFHINTFNAVEETESWRRRTLAASGEKNAKSARETEP
>A0A1X1B0I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia sp. 1135|TrEMBL
MIGSADRATWPGSPGQSYDCRVSSQLPQTSIVQRLAEPHPGPVPFSVEFYPPRDEQAEAR
LWRAVRIFERMGPAFVSMTYGAGGSTRDRTLRIVGQLARETTLLPVAHLTAVGHSVEELR
AMVGGFADQGITNILALRGDPPGDPLGEWVKHPEGLEYAEQLVRLVQELGDFNVGVASFP
EGHHRAPDLDHDTKYLVSKLRAGAQYSITQMFFDVDDFLRLRDRVVAADPEQGAKPLIPG
IMPITSLASVRRMVELSGSVLPADIDRRLAAAAGGGPEEDREAVRAVGIDLATQMAQRLI
AEGVPCLHFCSLNFAKATSEVLERLGMNVMAA
>A0A081FZR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacterium sp. AK27|TrEMBL
MQLSLREKFADPSRGIYFIGTTPPRDTTSDEQMKEIAGKLLSRLAKLEYDGLIIYDIQDE
SARIDTPRPFPFKETRDPREYSRLISDLSNRETITYKSVAQRDRADFDRWLDEAWNDFGL
RNLVLVGSPSSEGDIRLTLPEAYAAINEHQYPFHLGGVTIAERHAIKGNEHERLLNKQAN
GVEFFVSQAVYNPQATIDLLASYARSCREQGITPKRIILTFTPCGSAKTLEFMEWLGISV
PPATRWRILDAQNPLAESIRICQNSLDQILEACIPLGLPLGLNIESLTNRKEEIDASIQL
YRLLKATLDLKLAEHQLEG
>D2V2R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naegleria gruberi|TrEMBL
MKIIDKINQCIEENKTFYSFEYFPPKTDAGVENLYQRLQRMAKLAPMFIDITWGAGGSTA
GKTIEIGATAQNMIGVETQIHMTCTNMKVEELDKAIQTAKDMGISNILALRGDPPLGSED
WEQTDGGFKYARDLISHIRKTHGDYFGISCAGYSEGHPEGDYQKDLMYLKEKYDAGADFV
VTQLFYDWQQFLKFVKEAREIGIKCPIIPGIMPINNHASWQRMTTFCKTSIPQNVHDEMA
KLNLEDDNEVKAYGIKLCITICRALMDNGIRGLHFYTLNLEKSTEAILEGLELSPKESIP
RSLPWVKPANAKRLAEEVRPIFWSNRVKSYIDRTQHWDEFPNGRWSDSRSPAFGELGEEI
AYFYRRKFGEKENIVAAWGAEHANLESISQVFVNFIEGKIPFLPWNEQSTSPETNIIKNE
LIELNKNGFLTTNSQPKVNGVSSSDDSVGWGPLNGFIYQKAYVECFISPQHLETLENIIK
EKYPMVTYQALTKDGRVKTNIQGDNYVNAVTWGVFPAQQILQPTVVDSNAFLVWKDEAFQ
ILDTHWLSLYEEGSQAHTLLKTISDEWYLINVVDNDYINGDIFKLFREVSQQKQ
>A0A4R4VPT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora terrae|TrEMBL
MTTPQEVAGPRSGLAALVRNISYEVMPFKGTEQAVVEAVPISVPLTVTATEAKGLDATLG
LAERLLARGYRVAPHLPARQFVDRAQVSDVLDRLTAAGADSVFVIGGDAPRPAGTFPDAH
SLLQVMAEIGHPFAEVGISGYPEGHGSIPRPVVDEALRRKAPLATRVITQICFDAATTRD
WASGVGLPVAVGMPGPVGRQKLVRISAGVGLGRSARFLQKQQGLLRRFLLPGSYDPTRLA
RRLGAVAPGTNLRGLHIFTFNELAGTERWRQRLLDSLAEAR
>A0A1F2YDE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium RBG_19FT_COMBO_70_19|TrEMBL
MTAQSRLERLVRSGTFCVTAEVVPPRSADGAAVRAQARELVGYADAVNVTDNPRAAAHMS
PVAGVALVGAAGLEPTMQLTCRDRNRLGLTSDLLGGWALGARNLFCLTGDPVEVGDHPDA
ATVNDVTVEGLVRLATDLREHGRLLSGTVVEDPPGFFVGVADVPLAPSYDPARLEAKLDA
GAGFVMTQIVYDVEALAAWVEVARVRGIVERAALIVGVAPLGSAKQARFLNEKVPGVTVP
GELIRSLEDAGPDAASVGVAQCIEVVRRLRSLPGIAGVHVMGMGREEGVRAVVEGADLLP
RPAALRA
>A0A4Q7T6L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. BK036|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGISFEFFPPKTEKMETQLWEAIRTLEPLAPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGDPNADIDNL
KRKLDAGASRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPSETVAAA
>A7VHI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. L2-50|TrEMBL
MKIRDIIGQEKATLSFEVFPPKKDTDFASVEAAALGIAALRPSYMSVTYGAGGSTKGHTI
KLANEIQEKYGVPTIAHLTCVCANKDSIRTALSEMKNAGIENILALRGDIPKNYDGQVFT
DFAHASELVKLIKESGDFCVGGACYPEVHPDSANKQDDIANLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRIREAGITVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEVAAGIQANLSDILPV
>A0A5M8FL61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiohalocapsa marina|TrEMBL
MSNTPTPSGNRPDIRSRNFSFELFPPKTADGLDKLKLAVRRLQAVGPLYFSCTYGAGGST
RERTFETVDWLREQGIETAPHLACIGSDKDEIGAIVRRYIDEGISRIVALRGDLPSGMGR
TGFGTFRYANELVEFLRAEFGDHFHIEVAAYPEFHPQAPSADADLANFKRKVEAGADAAI
TQYFYNADAYFGFMDDCERLGIDIPVVPGIMPITNYSQLARFSDACGAEIPRWIRKRLEG
YGDDRDAIRAFGHDVVLDLCRRLLDGGAPGLHFYTMNQSAPTLRLWEDLGLPTSAA
>F0XZS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureococcus anophagefferens|TrEMBL
MPKINDLIAQKAAKGEDWVSYEYFPPRSEQGVKNLEARFERMKAARMPLFCDMTWGAGGS
TSDLTMELTLKMKQLGLEPNMHLTCTNVAKADVVKALKTCRDNGVANIVALRGDPPVGQD
KWEATEGGFECALDLVKFIRETHGDYFCLSVAGYPEGHPDTIVHKVFVCPDASFKLEMDY
LKKKVDAGADMIITQMFFDASTYGAFLKECRKCGIDVPVVPGIMLVQAAGGFRKMTTMCK
TRVPEAVAKAVDTRASDDAELKSYGVDLGVEMSHQLLKYGAPGLHFYTLNLEKSTLAIAD
RVAADRAKAAKGEPDWLKLAVGVAAVAGLFAFALKKRA
>A6L4W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 / NBRC 14291 / NCTC 11154)|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKDGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVEAGADYVVTQMFYDNRKYVDFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAMKCKDDKEARALGIEWCINQCRELIAYGVPGIHF
YTVGAVDNVKEVATAVY
>A0A853UYZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. HMSC063F10|TrEMBL
MSQFLNQLQNNILVADGAIGTILYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKPFGLEHKVKEIHKAAVKIAKRAATKNTFILGTVGGFRGIKQDDISLSTI
QYHTENQIDTLIEEGVNALLFETYYDLDELKRIVTWTKRNYDIPVVAQLTASNTTYLVDG
TEINDALAQLVTCGADVVGLNCHHGPHHMEKSFSHIALPDNAYLSCYPNASLLDIENSEF
KYSDNAQYFGAVAEKLIEQGVRLIGGCCGTTPQHIHYIKSSVSHLSPVNHKKVIPIHKKS
NQRRTDSIKQSLTSKVKQGPTVIVELDTPKHLDTDLFFENIGKLDAAHIDAVTLADNSLA
TVRISNIAAASLIKQRYDIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGSTNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKIASGMSYFITQPVYSKEKIIQVYEATKHLNIPIFIGIMPIASYNNALFLHNEVPGI
KMSESVLNQFKAVKDDKEKTKELSLRLSKDLIDTVHQYFNGLYIITPFQRVDYSLELAAY
SRSITTNKEAIL
>A0A2R8ACC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontivivens insulae|TrEMBL
MARPHLSFEFFPPHSPAANMRLWSSVERLAPLGPDFVSVTYGAGGTTRDRTRAAIATIKE
RARLQVAAHLTCVDATRSETLDVARGFRRMGVKRIVALRGDPPKGADRFVAHPDGYGSAA
ELVEGLMRDGDYDITVAAYPEVHPEAASVSADIDNLKRKFDAGAQRAICQFCFETDTFLR
FRDACADAGIAQPILPGILPVENFAKMQGFAARCGAGIPEWMKAAFGNAQTEAEAKLLAV
AIAAEQATDMMEAGVDHLHFYTLNDPDLTWDICAALGLEANDMQAVAGGAA
>A0A378QB95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella osloensis|TrEMBL
MTTMTTPFSFEFFPPKTDDGQTKLLATFDELNALKPQYFSVTYGAGGSTRERTLGIVKAL
SEKSDTPITPHLSCIGDDKAKIGELLDYYKSLGINRLVALRGDLPSGMVGLGELPFAVDL
VKYIREHSGDYFRIKVAAYPEMHPQAKSFDADIQNLLNKYRAGATEAITQFFYNADSYLY
LRDALAKKGVTQDQFPIIAGIMPITNASNLIRFADGCGADIPRFIRKQLADYGDDKKAIR
QFGFEVVVNLCERLIAEGVPSMHFYSMNQVSPNKQLIEALGLV
>A0A2E3IG54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibacillus sp|TrEMBL
MQNTPHISDLLSQGNPSISFEFFPPKSAEASDRLFSTIHELKQLNPSFVSVTYGAGGSTR
ELTHKLVLRITEETTIPAIPHLTCVNHSQAEISEILSGYANAEIPAILALRGDPPEENPE
YNRAKDAFCYAADLVCFIQNFNRETSNPRKRFGVGVAAFPEGHPDTQNRLKEMDYLRQKV
DSGADYICTQLFFNNYSFLDFRDRCRLAGIHIPIIAGIMPITTKSGMVRMADLAAGVHFP
AQLQRMLFSAQDDPVAFEKAGTDYATSQCRELLAEGVDGLHFYTLNRSGATAQIATALDL
GQK
>A0A2W1K3A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesonia sp. K7|TrEMBL
MKVTEHIAKNKGKGVFSFEVLPPLKGQNIQSIFESIDPLMEFDPKFIDVTYHREEYIYKT
QSNGLYKKHVVKKRPGTVGICAAIQNKYKVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VLALRGDAVKTETYFRAEPDGHHYASELISQLSDMNKGKYLDEELKNSSATNFCIGTAAY
PEKHMEAPSLESDLNFLKKKIENGAEYIITQMVFDNQKFFDFVARCRKGGIKVPIIPGLK
PLSTKRQLNLIPHRFHVDLPDDLVNEVLKCKNNQAVKQVGVEWCIQQSQALLKLGVPALH
YYTMGKSENIKEIAKRVF
>A0A2N1DE77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraglaciecola sp. MB-3u-78|TrEMBL
MASYAQGIDALNQSLSEVKGIDVSFEFFPPKTESMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQAETGIQAVPHLTCVDATREELIEIAKDYWKSGIRKIVALRGDLP
EGVEKPQSYASDLVALLKEVADFEIAVAAYPEKHPEAPSSQFDLLNLKRKADAGATEAIS
QFFFDAEVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLQRFAGFTNVHVPQWLHKMYDGL
DKDDQTTRNLMGANISMDMVKVLAKEGVRKFHFYTLNRSELSYAICHMLGVRAD
>A0A1E9BYW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. HMSC067B03|TrEMBL
MRVIDLIHNSEKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFSREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLFWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEALKCKNDKEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A1B8PUP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella osloensis|TrEMBL
MTTPFSFEFFPPKTDDGQTKLLATFDELNALKPQYFSVTYGAGGSTRERTLGIVKALSEK
SDTPITPHLSCIGDDKAKIGELLDYYKSLGINRLVALRGDLPSGMVGLGELPFAVDLVKY
IREHSGDYFRIKVAAYPEMHPQAKSFDADIQNLLNKYHAGATEAITQFFYNADSYLYLRD
ALAKKGVTQDEFPIIAGIMPITNASNLIRFADGCGADIPRFIRKQLADYSDDKKAIRQFG
FEVVVNLCERLIAEGVPSMHFYSMNQVSPNKQLIEALGLV
>A0A416F4T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF32-7AC|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPELCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A091NA35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acanthisitta chloris|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNY
HIVNVQGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A5C4WNH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides albidus|TrEMBL
MRNKDAATLRHLLTHARYEILPTKTIEEKVLESVPTSVPVTVTASPSMGLERTVETAERL
AAQGYSVVPHLAAKMVTGRSQLAELAERLTAAGVTTIFVPGGDAEPAGDYKDALSLLEDH
TDLGRPFAEVGVAGYPESHPSIHDDLTVQSMWDKRKHATHIVSNLTFDPDVVKDWLHRMR
LRGIDLPVLLGVPGPVERTKLLSMATKIGVGDSTKFLSKQKGLMARLVAPGGFTGESFLT
KCAPTIGEPEVKVTGLHIYTFNQVAETEAWRQDWLSRIAKE
>A0A1T2Q8B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDSDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAALNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLKQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2C2B885|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSLGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1J9WI95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEYLVKYVR
EKQEVKEGIN
>A0A1G4L4M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALMEEVYEATKHLEQPLFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7D3Z1Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEALKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEAIKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7L9UKJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum|TrEMBL
MHSPMFTLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPGLKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRAAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNAEPLFLGTQG
>A0A363U436|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MNKFLELLSSQTLLADGAMGTMLHARGVGFDKCFDELNITNPSAVAEIHREYIEAGAQLI
ITNTFGANRFKLSKHGLQDDVVEINKAGVDLAKRIVAASFKDVLVAGDVGPLGVRIAPYG
RVQLEEAREAFAEQIGALADAGADLIVIETMSDLYEIREAIKAARKVCNLPVVASVTFTR
DDRTLLGDDPTKVARVLNEAGTDVIGVNCSGGPAQLLRILKQMGQAVPNGRFWVKPNAGW
PEQVGGRIMYPADAEYFGDYALLFRDTGACIVGGCCGTTPQHIAAMRKALDTASNSDQSQ
IVILPQEELSETAQEQPTKFAQKLTSGGFAVSVEMDPPRGLSTHKLIAGASLLADAGADV
INVADSPMARMRMSAWAVCDVVQRQVGVETTLHFPTRGRNLLRVQGDLLAAHALGIRNVF
VVMGDPTAIGDYPEAMDNYDLVPSGLIKLIKQGFNAGVDHSGTSIGQPTNFFVGAALNLC
PPDIDTEIKNLHRKVKAGADFFLTQPVYNPNDGPRILEGYEAKHGKLHQPILAGVLPLVS
VRHANFLHHEVPGVFIPEETRKRIEAAGEDGVKAGVEIAVELVEQLKAWAGGVYVMPQFH
KYDMVAEIIEAVR
>A0A2B4LKW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGTVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRSAVKLAKASVTEKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEALKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMAPKFIEQGVRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIEAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRHRMDGHETKEEAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7W9EBU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola|TrEMBL
MIDPDTPSLASTITEAYSLEVSAKHIAGLAAAAPRITRGATIAIPYLPNQDDDARLAAAR
MVRALGFQPMPHLSARRIASREQLHAFVSRAVDDAGVERCLLIAGDPPAPLGPFPDSLSL
IDTGIFERSGIRTIAVAGHPEGHPSMPAADRWEVLQRKCRSIAERGMAPLIVTQFAFDAD
IVLTWLQALRARGIAHPVRVGVPGPAGVAVLARYAASCGVGACASMLSKYGISLGKLLGT
AGPDRFVERLATGLTDAHGEVRMHFYPFGGIAQTVAWVEQYRSRSARV
>A0A1D3QV92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGVMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7W9N5X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola|TrEMBL
MSARRSCDAARFHCAPWHCFHSIRADGAAPPNHPHRTTSPLIHPETPSLASTITDAYSLE
VSAKDIAGLAAAAPGIMRGATIAIPYLPNQDDDARLAAARMVRKLGFEPMPHLSARRIAS
LDALHAFVRRAVDEAGVARCLVIAGDPASPAGPFSDSLSLIATGVFERSGIQTIAVAGHP
EGHPIVHATDRWDVLERKCRSIAERGMAPLIVTQFAFDADIVLTWLSALRAHDIQHPVRV
GVPSPAGVAVLARYAARCGVGACASMLSTYGISLGKLFGTAGPDRFVDRLATGLTEAHGD
VRLHFYPFGGIAQTVAWVERYRSRIARPGVD
>A0A838MD39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiaceae bacterium|TrEMBL
MAIDDRNGKTAERLRYSFEFFPPKSEDMADQLWKTVDELADWAPDFVSVTYGAGGTTREP
TLSTVRRLIAETPLRTAAHLTCVGATKEEVHQVVEQFRAVGVKHFVALRGDPQGGMGTPY
QPHPGGYANAAELVAGLRELGDFEISVSAYPEKHPESPDAASDIDMLKRKVDNGACRALT
QFFFDNDIFERYLERVRAAGISIPIVPGIMPIQNLTQLKRFASMCGASIPGFLDERFAGL
DEQPQARAEVAAEVAAEQIEDLVRRGISDFHLYTMNRSALVTATLGNLGLRPLAARGREG
AGAAA
>J7SV85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sporogenes (strain ATCC 15579)|TrEMBL
MRIYLGILNLREISFRFFIFKVSQKLNICNTLYKKLLGGFRMHIKELFNQKNLVFSFEIF
PPKATSSVKTIYETLEELKDLTPDFISVTYGAGGSLKDNKTCELSSLVKNKYGIEALAHL
TCINSTKDDIDLIIKELKENNIKNILALRGDIPKDKNIIGEYNYAFELIRKIKENDNFGV
AGACYPEGHIECESLEKDIKELKRKVDAGAEHLISQLFFDNNIFYEFLNKAQQKNINVPI
QAGIMPVVNKKQIERIIKISRATLPKKFMKILDRYEYDKEAMKDAGIAYAVEQIVDLVSS
GVKGIHLYTMNNPYIARRITESTKSIFNSINKDVAV
>A0A2N2FJ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-8|TrEMBL
MRIADLIPTRKPFLSLEFFPPKERDTWPKFFEEVEKLKVLDPLFVSVTYGAGGGTQANTL
DIVTHMKNDLGLEPMAHLTCVGASSDALHGFLKAITEAGIQNVLALRGDPPRNVENFSFE
GQEFQHASDLVRFIRRHYPDMGIGVAGIPTVHPESASPEEDLKWLKHKVDAGGQFVVTQL
FFENELYLGYVQRLRALGVSVPIVPGIMPILSMKSAEFIAGLNGRAVFGGFFETLEATFA
KGGDVAVRELGLAHATAQVQGLLDAGVPGVHLYTLNRAEACLSIMNNIIIR
>A0A454XU51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas testosteroni (strain CNB-2)|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPEFCSVTYGAGGSTQAGTFTMVRDIQNE
GVGAASHFSCIGATHEKVRAELNELKAMGVKRIVALRGDLPSGYGLGGEFQYASDLVAFV
RQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VRALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A1H3AME7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora shandongensis|TrEMBL
MTAVVDRLRTEKTTFSVEFFPPRGDDEERVLWRAIRELEPLDPAFVSVTYGAGGSNRDRT
IRTTGRIAQETTLTPMAHLTAVDHSVAELRNVIGWYAASGVQNVLAVRGDPPGDPNGEWR
RHPDGLTYAEELVRLVRELGEFCVGVAAFPHGHPRSSDLETDADHLVRKIRAGAGFAIAQ
LFLEPEYFLRLRDRMAARGCDVPLLPGVMPITTPRVLGKFGELAGVPVPAEVSEQLLPLA
EDPAGFRAAGVDLVTRLCERLIAEGVPALHFYTLNRSKATRQVVANLGLGAG
>A0A1H2H6X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stappia sp. ES.058|TrEMBL
MPSTDKYRRFELGSGADVSVSFEFFPPKSEKMEASLWRAVERLQPLSPNFVSVTYGAGGT
TRERTHRTVERILRETDLSPAAHLTCVGSSREEVDAIVRDYQALGVKHIVALRGDPVEGI
GAVYKPQPGGYAYSCDLVEGIRRIGDFEVSVSAYPERHPESPDWSTEIDNLKRKVDAGAT
RAITQFFFDNDLFETFMEKVRAAGIDIPIVPGILPIVNFETTMVFSAKCGTSIPDWLVRR
FAGLDQDVETRKLVASAVACEQVLDLVDRGVSDFHFYTMNRAELTYAICHTLGLRPAPEK
KQAA
>A0A5M6IC71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseospira marina|TrEMBL
MTLDPTTAARPALTLPLCNHLPDDVKVSFEFFPPKTDKMAESLWAAVKRLEPLDPAFVSV
TYGAGGSTRERTHETVTRIARETALKPAAHLTCVDATREEVDTVARQYWDAGIRHIVALR
GDAPDSDGVYRPTPGGYAFAADLVAGLKKVADFEVSVAAYPEPHPEASSAEADLDNLKRK
VDAGATRAITQFFFDVDVFNRFRDRAAAAGITVPIVPGILPVSNFTTVTKFAGMCGASIP
QWMAETFDGLDDDAETRKMVAAMVAAQQCRGLAAAGADQFHFYTLNRADLTYAICHVLGV
RPPMPVPSPAMAEA
>A0A511NE80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Empedobacter brevis NBRC 14943 = ATCC 43319|TrEMBL
MNSKDCSEKPARRERPNETLALRHLQHKLLQIRHTNFATRLKTMKVTQHIERANGKPLFS
VEILPPLKGQDVNATFKTLDPLVELNPAFIDVTYHRQEYIYKQKENGLLKRYQVRKRPGT
VAICAAIQNHYKVDAIPHLICGGFTKEDTEDALIDLNFLGIDNVLVLRGDPIKSEKSFVP
EMGGHAHASDLIGQITGLNTGSYLDDELQESHPMDFCIGVAGYPEKHFESPNLAMDLHYL
KKKVELGADYIVTQMFFDNQKYFDFVNKCREMDIHIPIIPGIKPLTTFSHLTSIPQNFYI
DLPEPLSMEVLKAKDKEAVKQIGLEWSIHQCKELIEFGVPGLHFYTMSNSNNTKTVAEAI
F
>A0A523VBN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MTQASTELAAGSNLEKVFRAGHFAVTGELGPPASSNRKVVEDKAQHFKTTVDAINVTDNQ
TAVVRMSSISVGTILLGMGLEPVIQMTARDRNRIAIQADLLGASALGVKNLLCLTGDHQM
FGNHPVAKGVFDMDSLQMLSMVRDMRDKGVVQSGDEMDVPPRFFLGAAANPFAPPYDFRI
HRLAKKVKAGAQFIQTQIVYNVDRFAEYMKRAGDAGLLDNLYVMAGVTPVKSVGAARYMA
SQVPGLEVPDEIVQRMVDSGAGIPKEDKAARRAARREEGINICVEIIQRVREIAGVAGVH
IMAIEWEEAVPTIVERAGLLPRPKV
>A0A3A9FDH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium 1XD42-54|TrEMBL
MKISELFDRGEFVVTAEVGPPKGIHIEHILEEAKTYLSGITAVNVTDNQSSVMRLGSLAT
CKALKDEGLTPIFQLTCRDRNRIALQSDLLSAAMLGIDNVLCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTIKQLESGVDLGGNELVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGVHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKVPDLLKQAGI
>A0A1X0KBB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium scrofulaceum|TrEMBL
MSAGPECPKRMEFGPCGGVRPDGQCEMRPGACAFDHVVAWSGHQPAPRRVRAPMVLTDFS
CTPFDRDDLAATAAVLAPGCDAVLVGEHQNKPDFPPTLLGSLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSVGVETVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASTGVVAAVP
ETPTAPPVHARPARLVEKQRAGASLAVLNHVPFPDMVAGFMTTARAAGLTIPVIAAVAAF
TDTVSAAVLQGLPGLELDQAVTDRVLSAADPVGAGIAAAVDEARALLSIDGVEGVNVSGP
GSASGPRIGAEIKAEIGRRIREEYR
>A0A7H9CGT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Campylobacter infans|TrEMBL
MLRQKIKANSAGIILYGLTPPRIGTDFSKCEQIAKTQLERLENSGIDGLVIYDLQDESNR
NQNERTFAFKDTIPPEIYHKNYLKNAYNAVIYKAVSKYNSNDLKEFLQNNNDLISVFVGV
SSKKDIPKTKLSDAYKIKAQVAPNIILGGICIPERHIKKGDEDERVAHKIAQGCEFFITQ
AVYNPKNAIKFLDDYSYLCAYENVPRVPIIFTFTPCGDLATLSFMRWLGIDVPLSFQAAL
NASSNPLEMSIQTSLQSFKLLYDTGKKLGLSVGANIESISAKKSEIDASIRLLALIKNQV
L
>A0A6N6LBG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSTTPFSIEFFPPQTPAGVDKLRATRAQLAQLKPEFFSVTYGAGGSTQERTFETVFEIQG
EGLPAAPHLSCIGATRESIRDILKRYQDKNIRRIVALRGDLPSGVVDPGELRYANELVEF
IRAETGDWFSIEVAAYPEYHPQARSPQADLAAFKRKVDAGATSAITQYFYNVDAYLHFRD
ECDAMGIDIPIVPGIMPIVSFSKLARFSDACGAEIPRWMRRKFESFGDDSDAIKAFGADV
VTDLCARLLEEGAPGLHFYCMNMAGPTSTLVERLGLKA
>A0A6L3EL57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MYFEDEPVPGYSLPILPAHYSPGRFERVLRAGNFAVTAELAPPDSADPEEVLLRARIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYSTIMQISCRDRNRIAIQGDILGAAAMGVA
NLLCLTGDGVQAGDQPGAKPVFDLDSMTLLSTARRMRDESEFLSGRTLDSSPKVFLGAAA
NPFAEPLDFRVDRLAKKVEAGAQFVQTQYCYDVPRLKTYMERVRERGIDKEVFLLVGVGP
LASSRAASWIRDHVPGVHIPDEIIERLMKAEKPKLEGKKICIELIQQIREIPGISGIHLM
AYRQEESVAEIVDASGVLEGRVPWYPNRSSKSDTMRLAQ
>A0A7C4SPL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKSASRLERVLTEGHFAVTTECGPPRGAEPGVIRKKGELLKGFVDAINVTDNQTSVVRMS
SIASCVILKELGFDPIVQMVTRDRNRIALQSDILGAAALGMNNLLCLSGDHQTFGDDPEA
KNVFDLDSIQLIQLVKRMRDEGVFPSGKKIEGPPKFFIGAASNPFAEPFEIRPLRLAKKV
EAGVDFIQTQCIYNLDRFEKFMDEVRKLGLHKEVKILAGVTPLKSAGMAKFMKKNVAGMD
VPDAVVKRLADAPKEQQPEVGIQICVESIARLRQIEGIAGVHIMAIEWEQKVPEIVERAG
LLPRPQV
>A0A7C7I7C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIKDILKKTRTISCEFFPPRAEEGIPEVFSAVDRLKAYRPDFVSVTYGAGGSTRAFTER
ITSEMKQQADLEVMAHLTCVGQTKEEIHSVLERLDQTGIENIIALRGDPPRGETDFVPVE
GGFQHATELIEHIHNNFQMGVAAACYPEGHTESPNLSADLDYVKQKVDKGADFLITQLFF
DNSDFFGFLDRAKNAGIDVPIIPGLLPILSAPQIRRFASMCGASIPPDLDRQLDKCADDD
QSARALGIEHATKQVEELWANGVPGIHFYVLNRSYSVSKILDNLDLPGHSGRD
>A0A7V2KP43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTNLERVLESGAFAVTAEVGPPKGTSPRVVERKGEMLKGYADALNVTDNQTAIVRMS
SFASCVLLKHLGVDPVMQIVCRDRNRIAIQSDVLGAVALGIGNFLCLSGDHQRFGNHPTA
KNVFDLDSIQLIHTLRTMRDEGKFLCGEDISGEVPLYIGAAENPYADPFEFRVTRLAKKI
RAGVDFIQTQAVYDVPKFARWMEMVAERGLDQKVHILAGVIPIRSAGMARYMRDYVSGVS
VPDEIVRRMEEAREAKEEGINIALETIEQLKEIPGVHGIHIMAVGWEDSVPLIVERAGLL
PRPIV
>W4AD91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL R5-192|TrEMBL
MKADLRKVMQERVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRSYRDAGTEI
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQISALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GEFRYGATPEYFGQTAVQFAELGARIIGGCCGTTPDHITAMKEALADYVPSPILEPDPSE
SKPRIVLHENVDERSGRGGQPTIVDLVKHRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALSINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLEKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A2S0LJQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 864|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVESCKNNNEVKQVGIEWAIQQSKELKATGVPVLHY
YSMGKSDNIVKVISEVF
>A0A2E9LNX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIKDILAKTRPVSFEFFPPRVADGIPAVLETLDELKVYCPDYVSVTYGAGGSTRAFTEE
ITFEAKRTAGVEVMAHLTCVGQTKEEIHGVLERLDAEGVENIIALRGDPPKGASQFVAVD
GGFKHASDLLEHVKANFDFGVAAACYPEGHTESIDLASDLKYVKQKVDNGADFLVTQLFY
DNRHYFEFVDRARAAGIEVPIVPGVLPVLNSSQVRRFTSLSGSEIPPELDKLLDKYADNN
SSALDMGVEYATEQVRELWDAGVPGVHFYVLNRSYSVSRILDNLMIPGHLRQD
>A0A0E2Q4F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus thermophilus M17PTZA496|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILLALDDMKGSAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRELDAVGVNRILALRGDIIPGVEPLKDFRYATD
LIEFIKAEAPNFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETARHIYEATHSLFKHHSQVGAL
>A0A2E0CL13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MDSSGISDISFNIISDFSPEKSSKSEHYDLNADLVLVASNPGQSTRIESSSRASYMQATT
SADCLATLTLRDLSPLAIESMVLGLMMWEVKGVVIVAGDPPLEDPCKGLTQDWPKRTTQQ
IRSLQKLIQDHKNPANPFVLGSVVDLGQSIDKAADLAGLKVKSGAEFFITQPIFSEGPAF
DFETLLMERLSGMEKPSIYYGLQLLEQESLCFSIVPDRVKEEVQRETNNLDSLTALAKKL
IASGQKQFYTIPPIFSGGQRNYQLCRDFNLLLKKLIMAPKGQERTDSHL
>A0A2W4L1C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MNSERKSRLLGNGEITVSFEFFPPKNEKMEEALWAAVRRLEPLNPAFVSVTYGAGGSTRE
RTHATVSRLVRETTLSPAAHLTCVGATCEEIDSIVRSYWEAGVRHIVALRGDPPGGVGTR
YEPHPGGYANAAALVAGIAKIAPFEISVAGYPEKHPESPTVEDDLDNLKAKVDAGASRVI
TQFFFDNERFLRFVEKARARGIWCPIVPGIVPIHNFKQVAGFAMKTGASIPAWLARRFEG
LDDDPATTHLVAAVVAAEQVMDLVDEGIRQFHFYTLNRADLVFAICHLLGLRPRPAVMQQ
AVTA
>A0A4Q9VDN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azotobacter chroococcum|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMTVARQLAGYDPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRSLLNTYQDAGIRRIVALRGDLPSGMGMASGELRHASDL
VEFIRAETGEHFHIEVAAYPEMHPQARNFEDDLRHFAAKMQAGANSAITQYFFNADSYFH
FVERARKLGVEQPIVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFG
EQVVTQMCEKLLDGGAPGLHFYTLNQAEPSLAIWNNLGLPR
>A0A3C0ECD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIKDILATTRPVSFEFFPPRAADGIPAVLETLDELKVYCPDYVSVTYGAGGSTRAFTEE
ITFEAKRKTGVEVMAHLTCVGQTKEEIHGVLERLNAEGVENIIALRGDPPRGATEFVPVE
GGFQHATDLLEHVKANFDFGVAAACYPEGHTESVDLVTDMKFVKQKVDNGADFLITQLFY
DNRHYFDFVERARGAGIEVPIIPGVLPVLNSGQVRRFTALSGSEIPPELDKLLDKYADNE
SGARDMGVEYASAQVRELWDAGVPGVHFYVLNRSYSVSR
>K2HBN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceaniovalibus guishaninsula JLT2003|TrEMBL
MTPPRISFEFFPPKSLDASFRLWETIRTLAPLRPEFVSVTYGAGGTTRDLTHDAVTTINK
RTGLRVAAHLTCVEATRDETLAIADSYADAGITDIVALRGDPPDGRRFAPHPGGFADTGE
LIAALAATGRFTIRVGAYPDRHPDAATDTSDVDWLRRKLDAGASSAITQFFFDADTFFRF
RDRCAAAGIDRPIVPGILPIESWKGVRRFAERCGTPVPAWLDDAFATAGQNGGSDALATR
LCTDLCTRLVEGGVEDLHFYTLNKPHLTRDVARALGVVPQGGLERVA
>A0A523WJX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTNLEKVLASGKFAVTAEAGPPKGTNAEVIQKKGELLRHCCDAVNVTDNQTAIVRMS
SLAGCMLLKQQGVEPVMQMVVRDRNRLALQSDVLGAVALGIGNILCLSGDHQKFGNHPTA
KGVFDIDSIQLIQTLKQMREEKKFLSGEDISGEVPLFIGAAANPFADPFEYRVSRLAKKI
KAGADFIQTQAVYDLDRFAKWIEMARERGLDKQTHILAGVIPIKSVGMARYMRDYVPGVN
VPDEVVARMEKADNAKEEGVSIILEIIEQLKEMSGVHGIHIMAVGWEDIVPEMVEQAGLM
PRPVV
>A0A352UF46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAKIPDLANNGSSSLKIICDFSPPRGGTPSLIGDLDGLNPDIVSVAYNPGKSVRVNPVAA
AAWIKANTKQDVVFTLATRDMNKVAIQSLLLGAQLLGLQNIVIVEGDGLSIRDRERFKAV
YDFQPTSLIESVRDMNQGKDFRGLKLRVATDFSVGATIDMGRPSDSEIPLAVRKAQTGAK
FFLAQAEFDPSVIARFRADFESHFDKGHAPPVFYGVQILAEDGIIFGNVPQGTRSELESG
RSGEEIALELIQNLMDQGVRTVYLVPPIFRGGRRDYDSARRVIESARRLAS
>A0A3D1M3D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MNNILEAIDRKINKPFVLCDFSPPKGGNPDLLADANELTPDMFMVAYAPGNSVRVNPIFV
AEWIQNKTKVPSMFAISTRDENKRAIQSLLLGAELKDLRNLLVVAGDKSVDGHLSMQVDM
KYSGPTELIASIKAMNDRRDYQGKPLIYPTRFCVGAALDLSRGWENEVRLTKAKVDQGCD
FMISQPVFDINLPHKFLSFYKDSIGENLNVPIMWGIQMVEKNTVSFAAVPEWLYQELENG
RLAHEITIDLIRQYREIGIETFYLIPTVFKGGRRDYVSAQAVIEEVG
>A0A0P1GNN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobius mediterraneus|TrEMBL
MPVSPSVPAVSFEFFPPQNLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRDLTRDAVA
TLHKTSGLNVAAHLTCVEATRTETLAIADEFAAAGVTDIVALRGDPPKGANGFQPHTDGF
ASSIELIEALAETGKFNIRVGAYPEKHPESPSSAADVDWLKRKLDAGADEALTQFFFEAD
TFFRFRDACAKAGIDDRVVPGILPIENFKGVAKFAQRCGTSVPAWVTQAFEKAERIDQQD
LLATALCSELCSELIEGGVDKLHFYTLNRPELTRDVCHVLGITPQVGLQNVA
>A0A3B8VHU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MLRDRAWLNPLRLRRPTVVSATSVSRWHAGVVKILRTWRQAGFYPIPVATTRDMLIFLYL
RRRSASKFMRHLMKISDILKNKRTLSFEFFPPRDEQGVERLFETIDHLKRYEPDFIDITY
GAGGSTQRLTVELCVRAYRDSGVTVMGHLTCSAQTKEMVHSVLKRFESEGIENVILLRGD
PPQGEDTFVPAEDGFSHATDLVQHTKENFDFGIAAACYPEAHPESLDADSDLYYTKMKVE
QGAEFLITQLFYDNEYYYAFVDRARQSGIDVPIIPGLMPILNASQIRRITSLCGATIPAG
LDRQLERHANDDRAVRQIGIDHTLRQAQELMASDVPGIHFYVLNRRYSITEILDNLQGLS
VGVTSS
>A0A523QCC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTNLEKVLESGRFAVTAEAGPPKGTSAAVMQRKAEALRHCCDAANVTDNQTAIVRMS
SLAGCVIMKQGGVDPVMQIVCRDRNRIAIQSDVLGAVALGIGNILCLSGDHQMFGNHPTA
KNVFDIDSIQLIQALKAMRDEQKFLCGDDISGEVPLFIGAVANPYADPFEFRVARLAKKV
KAGAEFIQTQAVYDIDKFAKWMEMVVERGLDKQTHILAGVIPIKSAGMARYMRDYVSGVT
VPDELVTRMEQAQDTKVEGAKVAVEIIEQVKEIPGIHGVHIMAVGWEDIVPEIVKQAGLL
PRPVL
>A0A547LN41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM4315|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVGRILNETSLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKEAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A7K8DLC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eulacestoma nigropectus|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDVCVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7G8QIE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. JUb54|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A8F6B4S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olleya sp. HaHaR_3_96|TrEMBL
MKVTEHITKGEGKTQFSFEILPPLKGQHIQSVFDNIDPLMEFKPPFIDVTYHREEYVYKD
LGDGLLKKHVVKKRPGTVGICAAIQNKYNVDAIPHILCGGFSKEDTENFLIDLDFLNIEN
VMALRGDAVKTETYFTPEKDGNAFASDLVKQVSQLNHAKYLDEGLLNCSATDFCIGVGAY
PEKHMEAPSLDSDIHFLKKKIKNGAEYVVTQMFFDNEKYFQFVDKCRAEGITVPIIPGLK
PISTRKQLNIIPHRFHVDLPEALIKAIIKCKTNAEVRQVGVEWCIQQSLELEKSGIPLLH
YYSMGKSDNIKAIAEAIF
>A0A520VM53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp|TrEMBL
MSPTMDQMREAQRALEAPLFSGLPGDIDVSFEFFPPKNAAMSETLWQSVETLAPLGPRFA
SVTYGAGGSTRERTHQQVVRIQNEARIPAAAHLTCVEATREEVDEVARHYWDEGIRHIVA
LRGDAPDGQSQYAPHPGGYANAVELIAGLKRVADFEISVAAYPEVHPDSPDRQADLDNLK
AKFDAGATRAITQFFFDPQCFFDFRDRAAAAGIDGEIVPGIMPVLSFAAVRRMSGLCGTA
IPPWMEGLFDGLDDRPAARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRAKAGR
>A0A0U3N9E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseateles depolymerans|TrEMBL
MSTPVSIEFFPPNTPVGSEKLKTVVQELRAVNPQYFSVTYGAGGSTREKTLATVAEIARQ
GFDAAPHLSCVGSTRENIAEILATYRAQNIRRVVALRGDLPSGTATAGEFRYAAELVRFI
RETQGADWDIEVAAYPEYHPQQRYAARDLQFFADKMKAGASGAITQFFYNPDAYFHFVDA
ARALGVDAPIVPGIMPINNYARIAQFAQRDGIEIPRWVALKMEGYMDDAASVRAFGLDVV
TRLCERLIAGGVPGLHFYTLNQSALTLELCSRLKLSSEL
>A0A432GE52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR324 cluster bacterium|TrEMBL
MHLIELYKKKDFVFSIEIFPPKTAKGMEKLKTTLEAFKSCTPDYISVTYGAGGTSRENTH
ELAAHIHHDLDVPAMAHLTCVAHTVEEIDVVLSNLKNSEITNVMALRGDPTAGTKHFVQP
KGGYHYASELITAIREHSDFGIGAAGYPEGHLENPDKDDDRKHLHEKIAAGAEFIVTQFF
LENTHFLRWRDQLRREGASVPLVAGILPPANWKATKHMSEMCGVSIPEDLAQALIKNETD
PEASREIGFDHVENQFEELLQEGVEGVHLYALNRLSTVERLGPILKDASGTISTPHL
>A0A2S6HNS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella xylanolytica|TrEMBL
MKITDILSQGKPTLSFEVFPPKTEDKYDSVEKAAAEIAKLKPAFMSVTYGAGGGTSKYTV
DIASALHHEYHVTALAHLTCVSSTKEKVHQVLGELKEAGIENVLALRGDIPADAPDKREY
NYASELIREIKETGDFCIGAACYPEGHVESANKTIDMDYLKQKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVVAGIMPVTNVRQIIRSCQLSGTYLPTRFKAIVDRFGEDPAAM
KQAGIAYATEQIIDLIANGVNAIHVYSMNKPDVALKIKENLSQIL
>A0A316BYV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudaminobacter salicylatoxidans|TrEMBL
MNMVTPRPPHPDENPAGIDLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSANPQDV
YERAAIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDV
LGAAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTP
PQVFLGAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMERARDLGFTEK
VFILCGVGPLASAKTAKWIRSNVPGVHIPDEIIKRLEGAQDQKKEGKQICIDIINEVKEI
PGVSGIHVMAYRQEEYVAEMVHESGVLKGRKPWKREGRADDQIVADRLEHLLHDEPTQQP
VQLVEKAAR
>A0A1H1KNR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium GAS113|TrEMBL
MTSIFRRDSAPDPGTPQTQVERYVSNGRLERVLRAGKFAVTAELDPPDSADPQDVFDRAL
LLKGCVDAINATDGPGANCHMSSSAICALLTRAGYEAILQVSCRDHNRIAIQGNMLGAAA
MGVANVLCLTGDGVQAGDHPEAKPVFDLDSTSLLSVIKRMRDEGMFLSGRRITTRPRFFL
GAVENPFAPPFDFRPLRLAKKIAAGAQFVQTQYCFDVPMLQSFMQRVRDLGLDRHCHILV
GVGPPPSARAARWMRSHVPGVHIPDSVIARLEGARDQKVEGRRLCIEIIQQVREIPGVSG
VHVMAHRQTQHVAGIVHDSGVLSGEPSPGELHEAPRATAP
>A0A1I5XUJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivivax halotolerans|TrEMBL
MTRPEISFEFFPPKNIEASFRLWDTVQTLAPLNPRFVSVTYGAGGTTRELTREAVSAIHK
HSGLRTAAHLTCVNATREETLGIARSFAEVGVTDIVALRGDPPKGETRFTPTDGGFANSC
ELIAALKETGDFTVRVGAYPDIHPEAPSDTADVEYLKRKFDAGADEAITQFFFEAETFFR
FRDACEKAGIDKPIVPGIFPIENWKGARRFAESCGTKIPAWVIEAFDAAERDGREDLLAT
ALCTELCTDLIEGGVDKLHFYTLNRPELTRDVCFALGVTPETRLENVA
>A0A1I0NYD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcaceae bacterium KH2T8|TrEMBL
MKLSEIYKKEGRVLSFEIFPPKHEEELNNIDATLEILCDLKPDYISVTFGAGGSSNNNKT
IAIARKIKEQYHVEPVVHLTCLTYDKAEIDGFCKELQANGIENILALRGDRNPNIAPKGV
FEHASELIEYIRPRTDFCIAGACYPEAHPESKDRVSDLRDLKKKVDAGAEVLLSQLFFDN
SYFYDFVEGARIAGIDVPITPGIMPCLSATSIKRMVTTCGASLPPAFEKIIKRYEDNKDA
LFDAGMYYAISQIIDLLTSGCDGIHLYTMNNPVVAGRICDGIKNII
>S3WXJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium sp. oral taxon 192 str. F0372|TrEMBL
MSDPSSIGELLATACSPTSSFEYFPPKDDESHALLLRTIDELEEVGPDWVSVTYGANGSN
RARTLAITTELGRRHRFRVMGHLTCTGQTVDELKAAIDAYGNAGITNILAIRGDMPGGAS
VAWEQYPGGLANATELVELIASRGPYSIGVGAFPDGHTGSSVEMDARILLGKQQAGASFA
ISQLFFDVEHYFAMIGRARSIGCTLPIVPGIMPVSSLKQLGRFAQMSGADIPAAMAERLM
TVSDDAEQVRQVGFQIATELCTRLLTGGAPGLHFYTQNRSRATREIVARLKGFI
>A0A6H9XC87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. AMSO1212t|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTQAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWIAHPEGVRYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVDSDTAHFVR
KCRAGAEFAITQMFFDADEYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAQRFERVADDPEAVRRLGVEQASEMCEKLLDEGVPGIHFITLNRSTATREVWQRLR
AAARV
>A0A7C6LTA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Intrasporangiaceae bacterium|TrEMBL
MATGLPSRLERPAHVTASIPDHLAGPTPSISFEFFPPRDDASEIALWQAIRQLEAVRPAF
VSVTYGAGGSTQDRTVRVTERIALETTLTPLAHLTCVNASVAQLRHVVGQYAAAGVRNIL
ALRGDPPGNVRGPWIPHPEGLDHADQLVALVRSLGDFTVGVAAFPDVHPESPDLEHDVQT
LIRKADAGASFAVTQMVFDADSYLRLRDKVAAHRDLPITPGLMPVTNVKQIARMSELMGT
PLPQAVVSRLAAAADDPAAVRAVGVEIATELATRMLAEGAPGIHFITMNRSTATLEVFGN
LDL
>A0A2R6F966|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QH_8_64_26|TrEMBL
MSLETRQTTTTAEGASTLLAEPRFELMPFDSFGDQLTYLPDGAEIAITTSPTLGLDATLE
WTEKGAERGYEIVPHIAARYVRDEEHLEEIARRLTEAGVSDIFVPGGDREDPVGEFDSAY
ELLVALDESEYAFEEVGITGYPEGHDFLDDRTLAEAMERKAPYATYIVTQLCYDSEAVVD
WVEEIRSRGIELPVEVGIPGVMKYQRLLEISQKVGVGDSVNFLRKTTGILGFARQLIGSR
GKYTPDELIEGLAPYAGDPEYGIRGVHVYTFNQSADTEDWRRRTVGG
>A0A6M7W316|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. NZP2298|TrEMBL
MTARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
IHVMAYRQEEYVAEIVDESGVLRGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A2D5GY09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia sp|TrEMBL
MRISELYQGGTFGLSVEIFPPRNESGDAELFKTLEELVRYQPAFVSCTYGAGGSTSKRTI
ELCALIQNQLHNTATAHFTCVNSTREELVEWLQNAVDAGITNIMALRGDPPAGQETFVPA
DGGLKYANELVSLIRKHFPDMGIGVAGYPECHPEASDSEVDLTNLKRKVDAGADAIYTQL
FFNNEHFYQFREQCLKAGIDRPIVPGIMPITEYRRIQRIMSMCSSEFPADLVGQLEAAQD
DLEAQFEIGVEYAIRQCEQLIKEGVPGIHFYVLNRSQACKRIFDALGFPETQENIAT
>A0A2S8K2L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium SEEP-SAG9|TrEMBL
GLTEKVHILAGITPMKSEGMARYMATKVAGMDVPEALIKRMGGVSKAKAPEEGIQISLET
IAALREVEGIHGIHIMAIEWEEKVGPIVEAAGL
>J0UYD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiovulum sp. ES|TrEMBL
MFEEFIRKLKSEEKFITLETTPNRSASLQKLVEKIEKSGVVENIDGFSTTDSPLAKMKYS
SLFSAVKIQNRFQKPVLATVSMRDKNKIALQSDLLGANDFDIRTILALTGDSAKISDQPN
TTGVFEGDSTLLLDIVNCFNTGIDFAGKPFAEGEKPKEIYPFTVVNSSARNSKTLLKKMV
KKIEHSTVGIISQPIFNREQAQNLLQIFESAKEKCGCPNPTAQLVFGLFPLTRFRTAQFL
ASHVPGIDVPQNWLDSLRIASQNSEEEEYRVGMDMSRELYRDILEIHPKIHMMTANRFEV
AKEVLT
>A0A1A7R9R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter gandensis|TrEMBL
MSKNIPISFEFFPTKTDAGAEKLKAVHQELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIKRFCDKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTESIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTNPTRQLVLDLGLA
>A0A1Y2F509|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Protomyces lactucae-debilis|TrEMBL
MVATGPARTTGRRITDKLEELDKDAPFYSFEFFPPKTDMGLENLHARIARMTKLEPLFVT
VTWGTGGSTADKSLELAKACERQHGLTTCLHLTCTNMDSHILDRALEEAKANGIRNILAL
RGDPPRGQEYWTPNEGDFVYAVDLVRYIRKQYGDWFCIGVAAYPEGHADNTHPEHMDPAS
ELPFLAAKVQAGADFILTQLFYDVDAFLKFQKLLSEYEGGMLARVPLIPAIMPIQSYQTL
MRMTALSHAAIPPAIHDAVEQVKGDDEAVKSVGVQVAIDMIHSLRHKTGGAVRGAHFCTL
NLEKSVALILKHGGLFRKASRETSPVGVRVPLRPSIVQNGTDGRHRPAADKIVDQMARID
MLTNPTNVNGQDTHDVDAQSLEEEAVSTSEGHGTQAREATWDEFPNGRFGDSRSPAYGEI
DGWGVSLGVHRTKALQLWGEPKTADDITRVFTRHLNGEIDATPWSNGPVSAETAYIKDHL
VALNTRGLWTVGSQPAVHCAPSSHPAFGWGPAGGHIFQKSFVECFMTESAWRRLRDSIKG
DPMVSYYAGTRMGRFETSMKDSGDCNAVTWGIFPGKEIVQPTIIEEVSFKAWKDEAFALW
AEWERLFEPASQSARLLRGVMERVWLVSLVHHDFKDEEALWRLMLEASLPQE
>A0A1W7A0X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodoplanes sinuspersici|TrEMBL
MLRRQADTSGGGGSGLGKILSGYSIEVMPRTAAKVERFADLLPRGTRVYIAHIEGTPIAD
MVTTARRLRDEGYAAMPHVPARIIKDTATLEDWVRQYRDEAGVEEALLLAGGPREPHGDL
HSAMQLLETGLFDKYGFRRLHVAGHPEGNRDIDPDGSSRQADEALLWKQSFSERTDADMA
IVTQFFFDAKPVIRWSERLHALGITLPIHVGVAGPTKLQTLIKFAIACGVGPSLKVLQKR
AMDLTKLMTPYEPFDVLGELAAYREAHPNSMIEQVHIFPLGGITASAKWANTQSNAVAEA
GVA
>A0A3S5E5S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter spanius|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGATRQDLRDILQTYKSEGVRRVVALRGDLPSGMGGDAGELRYASE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVAKVNAGADAAITQYFFNADAYF
DFVDRAQAKGVNVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNQAEAPLAVWKELAL
>A0A411WGA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jinshanibacter zhutongyuii|TrEMBL
MSFFHANQREALNQSLAEINGQINVSFEFFPPSNVEMEQTLWQSIDRLKNLKPKFVSVTY
GANSGERDRTHSIIKGIKDKTGLDAAPHLTCIDATPEQLREIAKDYWDSGIRSIVALRGD
LPAGGGKPNMYASDLVELLKSVGDFDISVAAYPEVHPEAKSAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPQWMSQMFS
GLDDDPETRKFVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPV
>A0A3S8X0U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC 01438|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVHAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PDALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A2W6YUU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp|TrEMBL
MGYRLRTAAQADQFLVTAEVMPPKGGNPEHMLAMGQLLKGRVHAVNVTDGSRAVMRMSSW
AAALLLQQQGVEAVCQVACRDRNRIALQADLMGAHALGLRNILALTGDPVKAGDHPEARS
VFDLESVRLLKLLEKLNFGVDSHDKPLTDGALDLFAGAAIDPQSPSWSGLQRRFEAKVKA
GAQFFQSQLITDFDRLAKFMDQVAAGYNRPVLAGIFLLKSAKNANFINRNVPGVNIPQTI
VDRLAAASDPLQEGVQIAAEQVQAARQVCQGVHLMAVRREDLIPQILDQGGVAPVDAALV
VCQDKILG
>A0A1W6ZL58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodoplanes sinuspersici|TrEMBL
MMRLRPPCNCLRVKSRRLSWRGFRHKRICSVGFDCRGGAYERRLMGKTLAPHRHVKSRNV
ATRHPCLTQSLDWGLFRRSSCVFLLHSVVPMASHNIVHLKDALKSGKFVLTAEITPPVSC
DSNDLLEKALPLRGLADAVNVTDGAGARAHMDSLTAATILLQNGIEPILQLTCRDRNRLG
LQAALMGAAAVGVRNLLALRGDDPKFGDQPDTKPVFDIDARGLLLTAARMRDAQELPSGK
KVGGKPDFFLGAADAPIDPAPDWKPVSLKGKVEAGARFAQTQFCMDAGVLRRYTERLTEE
GILPELAMIVGVVPFRSGKSARWIKNKLFGAIVPDAMIERMDTASDPIAEGKAILGDYLL
EISEIPGVVGAHIMAPNNDDAVPDVITEFRKRKGK
>A0A2E2C4L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia sp|TrEMBL
MRISELYQDGTFGLSVEIFPPRNESGDAELFKTLEELVRYQPAFVSCTYGAGGSTSKRTI
ELCALIQDQLHNTATAHFTCVNSTREELVEWLHNAVDAGITNIMALRGDPPAGQETFVPA
DGGLKYANELVSLIRQHFPDMGIGVAGYPECHPEASDSAFDLTNLKRKVDAGADAIYTQL
FFNNEHFYQFRERCQQAGINRPIIPGIMPITEYRRIQRIMSMCSSEFPADLVGQLEAVQD
DLDAQFEIGVNYAIRQCEQLMEVGVPGIHFYVLNRSQACKRIFDALGFPETQDKIAT
>A0A7W7R3X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora kifunensis|TrEMBL
MSRTPGTGGGRSLADVLAAGERSYSFEFFPPKNAEGERTLWQAIRRVETLAPTFVSVTYG
AGGSSRTHTVALAEGIRAQTTLRPVAHLTAVGHSIAELRRIIGRYAEAGIRDVLALRGDP
PGDPQGAWQPHPQGLRHAAELVSLLKSSGTLSVGVAAFPERHPRSPDWESDIRHFVAKCR
AGADYAITQMFFRTEDYLRLRDRVAAAGCDLPIIPEIMPATSFGQIRRFAELSNATFPAE
LAGQLAAAQGHPEAGHRIGVEHATAMGERLLAEGAPGLHYITLNSSTAAMEIHQNLGLHR
VQSALTTV
>A0A6N7KXB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces kaniharaensis|TrEMBL
MSTPSTLRERLRSGGPTFSFEFFPARTEAGARTLWEAIRRIEPLAPDFVSVTYGAGGTSR
DRTVEMTRRIATETTLRPVAHLTAVGHSRAELRRIIGQYADAGVRDVLALRGDPPGDPRG
EWHPHPDGFHHAHELVSLVRESGDFSVGVAAFPERHPRSPDWESDIRHFVAKCRAGADYA
VTQMFFRVEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIARFAELSGAVFPEDLAHRLH
AARDDPREGHRIGVEHATAMARQLLSEGAPGLHYITLNRSTATVEIHQNVQTSRSTGHAL
ARH
>A0A7Y9GQF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium immunditiarum|TrEMBL
MTVSSSLFTDRPGAVPFSFEVYPPRTPDAAAALHESVRRLADAGPRFISVTFGAGGSTGG
RSLELLRYIRETTDVEPLAHLTCVGSTTARAEALVRQFLDAGIDRFLALRGDPPAGLGED
DAFLGELTRAADLVRLIRRVRAERGIHDGPGAPALAVAAFPNGHPRSRHPRHDIDTLLEK
QAAGATFAITQVVFRADDHLSFADRAREAGVRIPILPGIMPVTSPARLRRVLELTGEAEP
ADLALELALAPDDESRREAGIAHAARLARELVAGGAPGIHLYAFNVHDTVLAVIREAGIP
THEKETAR
>A0A7Y9KJZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium immunditiarum|TrEMBL
MATITPAQNKAAARELVSGFSLEMTGKDVPGLQEAAHAIPQGTKINVTFLGNEDLDMRVS
AAKAVKDLGFVPVPHISARRLRSQDQLEEFLGRLQEVGATEHVFAVGGDPTEPEGPYPDS
LSVIRTGLLQKYGVREVSIAGYPEGHPDIKDDVLWRHLEDKSASLKEQGLDAVILTQFAF
DTDPVLTWIKGVRDRGIDTEIRIGTPGPAGIKRLLGFARRFGIGANAMIVKKYGFSLTNL
MGTAGPDKFVTDLSSLLADASAGSATGYGPVKLHFYTFGGLLATSEWVRDYLAAQA
>A0A1H0AAQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fictibacillus solisalsi|TrEMBL
MGLLKDLESKILIADGAMGTLLYSYGTDCCFEQLNLSHPEQIQSIHQAYIQAGANVIQTN
TYSANYIKLQRYGLEEQVKELNSAAVSLAKKAAGGHAYVLGTIGGIRGTGPSSLSLEEIK
RSFREQLYCLLLEGVDGLLLETFYDLEELEAVLKIARSQTDLPIISQISLQEVGILNDRT
PVNTAIKRLEELGSDIVGLNCRLGPFHMIKTLEEVEIPKHAFLSAYPNASLPSYVDGKFQ
YEGDAEYFKNSASLFRNQGVRLLGGCCGTTPAHIEAFATELDGLSPVTKKDVRRRPEPIA
VAPSGQKPQISLPKILQERRSVIVELDPPRKLDTTRFFEGAKALKEAGADAITLADNSLA
SPRICNTSLSSLAKAQTGTQAIVHLACRDRNIIGLQSHLMGLHTLGLHDILAITGDPAKV
GDFPGASSVYDVTSIELIKMIKQFNEGISLSGKDLGEKTHFTVGAAFNPNVKALDRAVQR
AEKKIEAGADYFISQPVYSEEKLVQFHEAVKDLPVPVYVGIMPLTSSRNADFLHYEVPGI
KLSDEVRSRMAEFKDDPLAAAREGLAISKSLIDAATELFNGIYLITPFMRYELTVELTKY
AYNIAPKNVRRIQNV
>B7AQD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Bacteroides] pectinophilus ATCC 43243|TrEMBL
MMESLREYLKGHRLITDGAMGTYYSEITNNPEAFAEFANIERPDIIERIHNEYIDAGAKL
IRTNTFAANTQMLGIGRDELKKLIEDACRIAQRCADGRAYVAGDIGPIKENAESEGSAVE
EYKMICDIFLDMKVDAIRFETFADFDDIKEVAEYVRSKSDMFIMADFCLNKNGFTAGGIS
AARIMQQAGQMDCIDSCGFNCGIGSGHMNNIMQKLTFAKDKYMSCLPNAGYPEQMNNRMV
FMNNASYFCDNMQKISAYGMNIIGGCCGTKPAYIRELCRRIGDAVPAGRTETSDGNEPVN
GNNPAEAADIRVNEKRPNEFMQLFKSGHKVVAVELDPPYDAKYDRLIEQAQYLKSIGVDI
LTFADSPMGRSRVDSVLMSLKVTQETGMMVMPHVCCRDKNVIAMRSTLLGAYINGIRQLL
LVTGDPVPSVSRVSTTGVFDYNSIRLMNFVKEMNQEHFADEPLYYGGALNVTLGRIDRIM
ERMQKKIDNGASYFMTQPVFSKEGIERLAIIKEKMDTKILCGIMPLVSYRNANFIKNEFI
GIDVPDEIVARYSPDMSKEEGEAVGAQIANELIGQMYDYVDGFYFMLPFNRVSLMDKINI
NNR
>A0A4P7GJY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides euryhalodurans|TrEMBL
MRNIAATSGGLADLLEQPRFEVLPTSGTADLVAAHVPGGRMLTVTASPSKGLEVTLALSV
ELAGLGYEVVPHLAARMVADEHHLAEVVDRLTEAGITRIFVPSGDAPEAGAYADAVSLLE
ALTALGRPFPVVGITAYPESHPTISDDITIQAMWEKRRHATEMVSNLSFDPRVVETWLGR
VRRRGVTLPLWLGVPGRVDPTRLLSVATRIGVGDSTRFLLKHKRTVARLASPRGFDTEKF
LRTLAPALVSDASVVAGLHVFTFNQVAETEAWRARLVAKLREGGASPRSTRRGPAATR
>A0A1I6Z4I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus amargosae|TrEMBL
MKRSLAVRDATTRKSLRQAFQGLGYEVIPFKKTEQSVLSCVPKDVRLTVTASPAKGQDAT
IDLSVALAGHGYTVAPHLSARQVRDRAHLADAVARCREAGITDVFVVGGDPTEDPTEFRH
AHDLLVALHELGHGFTDIGIGGHPEGHPTASTEILFQALKDKAPLATHIKTQIVFDPAVI
LTWARELRNRGIDLPVQVGVPGAVHRQKLLRVSGGLGIGESAKFLTKQQSMFWRFFIPGG
YSPDKIIKGLAPHIGKPDNSIDGFHVFTFNDLGPTEAWRQRMLKDLA
>H0GQA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae x Saccharomyces kudriavzevii (strain VIN7)|TrEMBL
MSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKT
LALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVE
AGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
AILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETVANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWET
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKA
WRDEAFSIWSEWAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETDELWEMLLDQA
>A0A100I555|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus niger|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVDQLVDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A430USI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus|TrEMBL
MKIRDLLKARKGPLFSFEFFPPKTPEGEEALFRTMEELKVFRPAFVSITYGAMGSTRDRS
VLWAKRILDLGLNALAHLTVAGQSQEEVAGVLDRFVEAGVENILALRGDPPQGERVFRPH
PQGFRYAMELVAFIRSRYGEGVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRMGIEIPILPGIMPITSYTQLRRFTEVCGASIPGPLLSRLERYQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGFKPQP
>F7Z770|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weizmannia coagulans (strain 2-6)|TrEMBL
MSAYPNASLLDYEEGRFTFTNNADYFKTCAEKLVEQGVRLIGGCCGTTPAHIKAIADGVQ
GLLPVTEKTVRPPKIEIAAAPAQYEPPLHEIVKKRHSVIVELDTPKTLNTARFFEGAKAL
HDAGIDALTMADNSLASPRISNTAIAAILKEKHGIRPLVHITCRDRNLIGLQSHLMGLAA
LGIDQVLAVTGDPSKIGDFPGATSVYDLSSMELIAMIKQFNDGISHSGKSLQRKTNFSVA
AAFNPNVRNLDKTVGRLERKIRHGADYFITQPVFSTEKIEQIHEATKHLDAPIYLGIMPL
TSYRNAVFLHNEVPGITLTDDILQAMEKTNGDPVKAREESLAISRTLIDAALAYFNGIYL
ITPLERYELTVECTRYIHEKTAVRSAGIF
>D4AR17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371)|TrEMBL
MEKISDKINALPKDAHYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEETKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFNYAVDLVRYIRKKYGDYFCIGVAGYPEGHADESHPEVQDPLKDLPYL
IEKTQAGADFIMTQLTYDIEAYKKYEALLRNHESGTFKTIPIIPGLMPIQSYHTLTRVTK
LSHAKIPPQILAKVEACKADDEAVKRVGVDIVSDLVEDIKKIATPGHRGFHFYTLNLEKS
VSFILERCNLIPPSSEAPSDSELEFESAVYAASGASNGVATPDGRSTNVNRLRASSMNSQ
PHNRVIVDRLTRASDRSERSSTVHETSAQTAGYPALNPPNRNTALQISEGLGSLGREATW
DDFPNGRWGDARSPAFGEIDGYGPSLHVTAQVARKLWGTPTSREDISNIFKRLLSGELHA
VPWSEGGAGEEGGLNPETATIKAELLKLVEGRGWWTLASQPAVNGVRNDHPVFGWGPRGE
GFVFQKAFVEFFCSGDDFHSKLKPLLQSYGHDEFAWFATNAKGDFQSSSSPETPTQPPTD
PTEVPFDADPLTEMDNGSVNAVTWGVFRGKEIVTPTIIEAVSFRAWGEEAFGIWEEWRRV
FPRGSPSEKLIREIKDDVWLVCVVGQRFGAGGDVGKESNEEDGKLLWKVLAGEQTK
>A0A4Q7LJU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptothrix mobilis|TrEMBL
MTVTSHLPAGLPLSLEFFPPKTPEGVIKLASVRQQLYALNPVFCSVTYGAGGSTQDGTLQ
TVQAILDEGHEGASHFTCIGATRDSVREKLALFKSMGLTRIVALRGDLPSGYGPFGEFRH
ASDLVAFIREETGDHFHIEVAAYPETHPQAKSPQADLQAYASKVKAGADTAITQFFFNSD
AYFRFVDDAAALGADIPVMPGIMPITNASGILRFADGCGAEVPRWIRLRLQSYGDDVESI
KAFGLDVVTDLCDQLRTAGVPGLHFYTMNASATVLEIVRRLQA
>A0A521WWP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacter sp|TrEMBL
MQSQKKHPQLFSFEFYPPKTEEGAASLQVVHSKLAKLNPDFFSVTFGAGGSTRDKTFTTV
VDIQSKGIAAAPHLSCVASTKDNIRAILKDYQDHGITKIVALRGDLPSGMMSAGEFRYAN
ELVEFIRQETGDHFQIHVAAYPEVHPQAASGSEDFKNFKRKVAAGANSVITQYFYNAEAY
FHFVDACEKSGITIPIVPGIMPITQYAQLFRFSEMCGADIPRWMRKRLESFGDDREAVQA
FGLDVVSNLCQRLLEGGAPGLHFYTMNQSAPTLAILENLQIKPQS
>A0A519U7M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp|TrEMBL
MKVTEHLSRATGKTLFSFEVLPPRKGENIHTLFSNIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRK
>A0A3T0FTK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. ISO98C4|TrEMBL
MISTDTPHLASTVTDAYSLEVSVKDIGALTNAAPRIVPGCAMFIPYLPGQNEAARLAAAR
TVRGLGFEPVPHLSARRIGSPEELQASVARLVDEAGVTRCLVIAGDPATAKGPFPDSVSL
IETGVFERAGIRSVGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
LVVTWLEALRARGMSHPVRVGVPGPASVAVLARYAARCGVGACASVLSNHGISIGKLFGN
AGPDRFVDRLVSRLTQAHGDVRLHLFPFGGIAQSVEWVAQYRSRNASQRLVGSEPADQA
>A0A822QGL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQYMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A6G2DDH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKK
>E7N338|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas artemidis F0399|TrEMBL
MAQGRAELRDYLKTAPLIFDGGMGTYYAQKLHTRGKGVELANIETPIVVGDIHTEYLRAG
AQAIKTNTFAANRIVYQGDEELVRRIVTAGWEIAAHAAAPFDAYVFADIGPVMGLPHADI
IDEYAFLADTFLALGARYFIFETNSSDEGLIETAAHIKQKCPEAFVLNSFSAYPGGYTRD
GRFVEDLVRAVAGSGYVDAVGFNCVNGTKQMKELIRHLGAHELPLSLMPNAGHPVVVDGR
TFYESAPDYFGSSLAAVRRDGVSILGGCCGTTPAHIKALCDALAAQGDIMPEEDEEAPPQ
VAELPKSPFYEALKSGAKPIAVELDPPETGSADKFMAGARELMAAGVNAITIADNPIARA
RMDAAMLAGRVHRELGIEPIPHMTCRDRNLNAIKSLLLGLSAEGVHNIITITGDPIPTAE
RDEVKSVYQFNSRKLASFITSLGSRGDVVPFHIFGALNVNAKFFGTQINLAKKKVEEGMM
GFFTQPVLSERAKENMRAVRETFPEALILGGIMPVVSERNARYMESEITGIHVEERIIDM
YRGLDREQAEELAVRLSLEIARDIEPYIDGYYIITPFSRTTLVARIVKELKK
>A0A2J7QG57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptotermes secundus|TrEMBL
MVWNFSKFCFNFRVSSASLAEQMHAQIDSGDKFYSIEITPPISVLDSCQLLRSLQNLYNC
SPLFTAITWHIKTSAMPVPPVLPFGKLRALRLGAEISNINSVLLHLSSVGLTKKQVCQVL
WYIRDMGIRNIFALRGDRPERNNDLKLDRGFPYASDLVSFIQERFGDYFTICVAGYPLGH
PEAVSFEQDLAHLKEKVDKGASFIITQFFFKAGDFVNFVQWCRRIGITVPIIPGILLIQD
YTSLIHISSACSVEVPRSVLDIIEPIKDNREAVRKFGVHLAVEMVSYLFSQNYSNAAHFF
TLNRQLSVIETCKCLGFCLLEPARPLMHHERCKKSKRIVKLL
>A0A8B4IIZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gordonii|TrEMBL
MVRHHSPSLSFEVFPPNPAVGNEKIIQALREMQDIAPHYISVTASNNKFNIEETTVRLAD
FIYNDLKIPTIAHLPAVYLTKEMVSDTLQALDKVGVHKILALRGDIFPDVAPKDDFKYAT
DLIEYIKEEAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDIPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGVHLYTMNNAATAHHIYQATHTFFS
>A0A6I6UXC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. R32|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLIQYKAAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHIEIAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A7Y3URE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SbB1|TrEMBL
MSLLKTALREKNFVCVMEFVPKPSAERFAAMEAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFANPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGLRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFFTLQLGF
DAAKHQEAMLWMRRQPTPKPMLACLMSLTHGRATMLDHVAGVTVTPSMRDMLEAETALSK
VFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQTRVHTLEQWAPA
WQASWQMPGLPAVIFHPPQASWRQGESQVDATFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPLWATRLGALVLHKVERAVKRPLVGCDTCGRCRLEDTLYVCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAAQTP
RRLSPQPTPRSQPES
>A0A0Z8ID58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEISVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARTIHQATHSLFKHYS
>I4G5B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa PCC 9443|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>A0A0H3MK08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O7:K1 (strain IAI39 / ExPEC)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>R6F3U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. CAG:520|TrEMBL
MNISDILTSGGGEKHFSFEVLPPLKGTGTERLFSTIEKFRDFDPAYINITTHHSEYVYRE
LENGQYERLRVRRRPGTVAIAAAIQNKFGVPVIPHIICSGATAEAIEYELIDLQFLGIEN
VLLLRGDKARDDSQFVPTPGGHAHTTDLIEQVNRFNDGFFNDGTPIKNPGKKFHYGVACY
PEKHEEALNMEMDLKYLKMKQDMGADYAVTQLFYDNRKYFRFVEKAREIGITIPIVPGIK
PLAKLSQLTVVPRVFRCDFPQELAVEALKCKTDDDARQLGIEWSTEQCRQLYKAGVNNIH
FYTVSAVDSVREVARRLL
>A0A123SFH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIHALNEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VHNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIINGLSPKEDFKYATD
LVSFIKEEAPQFDIIGACYPEGHPESPNAVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCILADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARTIHQATHSLFKHYS
>A0A5C6TRG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingosinicella ginsenosidimutans|TrEMBL
MSRFSPGPPLFADAAGDIALSFEFFPPKTEKMEAQLWESIKTLEPLAPRFVSVTYGAGGS
TRERTHATVARIVRETALTPAAHLTCVAATKGEIDDIAREYWAAGVRHIVALRGDPPEAG
QAYATHPGGYADAAALVEGLKKVAPFDISVAAYPECHPDSASRAADLDNLKRKIDAGADR
AITQFFFSAECFLRFRDEAAAAGIDAEIVPGILPVSNVAQTRKFAALCGATIPQWMDRLF
EGLDDLPDARKLVAATVAAELCAQLYAGGVRHFHFYTLNRAELAYAICHLLGVRPGGKSQ
EQAA
>G4CJ78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria shayeganii 871|TrEMBL
MMKKNTLSFEFFPTRTPEGREKQKITRKQLRQYRPAFFSCTSGAGGSTRDGTLQAVNDIM
AEGTAAAPHLPCVGMNEAELSDILHTYKNMGIRHIVALRGDIPSGMGAGSSGLRYANELV
ELIRRDFGDWFHIEVAAYPEFHPQARSAEDDINHFVRKVKAGADSAITQYFFNPDAYFRF
VDDVRGRGVEIPIVPGIMPIASFSKLARFSDTCGAEIPRWLRLKLQSYADDTASIKALGL
DVVTEMCEHLLEQGAPGLHFYTLNQAGLVSTICQRLGY
>A0A327KGT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoplanes roseus|TrEMBL
MVMALRTAARMQTGTQQDVAAIAAFMAATSFETTRLPDDDAAALRTHAAPGTPVYVSELP
SRPLAEQIAVVEAVRQAGFEPVPHVAVRNFGSAAALSDHIGRMVERAAVTRVLVIAGDRA
EPAGPFRAAVELIESGLLQSAGIGEVGIAGYPDGHPRIAPITLERALAAKLEAAAATGLS
AHVVTQFTMAPEPVVAWLTRLRDQGIDHLVRIGFAGPTSVAALLRFARICGVRASAQGLA
RNVGLARNMLGAAAPDRAVRGVAI
>A0A139N5Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gordonii|TrEMBL
MVRHHTPSLSFEVFPPNPAVGNEKIIQALREMQDIAPHYISVTASNNKFNIEETTVRLAD
FIYNDLKIPTIAHLPAVYLTKEMVSDTLQALDKVGVHKILALRGDVFPDVAPKDDFKYAT
DLIEYIKEEAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNEHFY
DFQDKCTLAGIDIPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGVHLYTMNNATTAHHIYQATHTFFS
>A0A7V2B2G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermus marinus|TrEMBL
MKVIEILEQAAGPLISYEIIPPRRGGSLEEVMAVVAELMPFDPPFIDVTSHAAEVEYEPL
PDGTLRPRIKRKRPGTLSICAAIKSRFGVETVPHLLCHGFTREETEDALIELHYLGIQNV
MALRGDSPGYRKPIPPDRTVNLYAVDLVQQIANMNRGIYLEPLEDAVATDFCIGVAGYPE
KHYEAPNLTWDILNLKRKIEAGAHYVTTQMFFDNRHYFRFVERCREVGITVPIIPGLKIL
TSKQHLQLLPSRFHIEIPEALAAEVEAAKPEHVPEIGIAWALRQAEELLEAGVPCLHFYI
MLRADYVRRVVEALRKMA
>A0A094C6U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4515|TrEMBL
MKTTWKDIQPVPTSQEFLDIVLSRTQRRLPTQIRAGFQISRIRNFYTRKVKFTQETFSEK
ISLILDGFPRLQDIHPFHKDLLNTLYDADHFRIALGQLATAKHLIETVSRDYVRLLKYAQ
SLFQCKQLKRAALGRMATICKRLKDPLLYLDQVRQHLGRLPSIDPNTRTLLICGYPNVGK
SSFLRSVTRADVDVQPYAFTTKSLFVGHFDYKYLRFQAIDTPGILDHPLEEMNTIEMQSI
TAIAHLRSAILYFMDLSEQCGYTVAAQIALFQSIKPLFANKLVFIVINKIDVMRPEDLDP
ESQAQLQALLKPGDVEMLQLSCTTEEGVQEVKNAACERLIADRVAQKLKAGTNSNGAVGG
RLGDVLARIHVARPMNGVVREAFIPDAVKEMKKYDKTDPERRKLARDIEEENGGAGVFNI
NLKDKYMLENDEWKYDKVPEVLDGKNVYDFIDPEIEAKLAALEDEEEKLEAEGYYDSEDD
LEDAEDADIRMKAELIREKRILIRNAAKMKKSLKNRAIIPRTLTKAKLTDMEDHLDSLGL
DTTSLTTRARSQSRGRSVVRSRTGTEDVMDVDSPEYEAKMRAKSRARSQSNRREDGVPEG
TARTKAERIAKLGQRHRNRMARAGEADRHVAAAMPKHLFSGKRGVGAAKLQLHRGVFQLE
KLNLGSSHTHTHTLHDAYQGHAKPGGAGEEAYFLVRVLPAKDCPGVAQSVYGLETCMHLT
CTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEKWVATDEGFQYARDLVRYIRKTYG
THFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATFIVTQMFYDVPNFLDWVSKVRAKG
ITIPIIPGIMPISTYASFLRRCNHMNARIPPGWIEAMEPVKNDDAAVREIGRGLVTGMCR
AILESGINHLHFYTMNLAQATRGVLEQLEMLPSEERPLKQALPWRQSLGLGRRGEDVRPI
FWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDAYGIGLKGSNEQNIKLWGQPKSVK
DIANVFLRYLNADVDSLPWSEAPISNEADVIKNQLVKLNERGLLTINSQPAVDGVKSSHP
VYGWGPLNGYVYQKAYLELLVAPELIDELLDRIAKDPEVTYYAVTNTGTLRTNAPSDAPN
AVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDWAHCHETSSPSRNVIQRVMETYYL
VNIVHNDFHQRDGLFSLFEGLSVPNIDEPAEGDVAPAAAAPATNGDKVEDAPPAIVSNVL
PVA
>A0A178F334|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton rubrum|TrEMBL
MEKISDKINALPKDAHYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEETKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFNYAVDLVRYIRKKYGDYFCIGVAGYPEGHADESHPEVQDLLKDLPYL
IEKTQAGADFIMTQLTYDIEAYKKYEALLRNHESGTFKTIPIIPGLMPIQNYHTLTRVTK
LSHAKIPPQILAKVEACKADDEAVKRVGVDVVSDLVENIKKVATPGHRGFHFYTLNLEKS
VSFILERCNLIPPSSEAPSDSELDFESAVYAASGASNGVATPDGRSTNVNRLRASSMNSQ
PHNRVIVDRLTRASDRSERSSTVHETSAQTAGYPALNPPNRNTALQISEGLGSLGREATW
DDFPNGRWGDARSPAFGEIDGYGPSLHVTAQVARKLWGTPTSRDDISNIFKRLLSGELHV
VPWSEGGAGEEGGLNPETATIKAELLKLVEGRGWWTLASQPAVNGVRNDHPVFGWGPRGE
GFVFQKAFVEFFCSGDDFHSKLKPLLQSYGHDEFAWFATNAKGDFQSSTSPETSTQPPTD
PSEVPFDADPLTEMDNGSVNAVTWGVFRGKEIVTPTIIEAVSFRAWGEEAFGIWEEWRRV
FPRGSPSEKLIREIKDDAWLVCVVGQRFGAGGDVGKESNEEDGKLLWKVLAGE
>A0A0Q9SCS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycicoccus sp. Soil803|TrEMBL
MALVHTSRDGRPGREPQSIPGMLAADHPSISFEFFPPKDDAGESVLWDAIRRLESVRPDF
VSVTYGAGGSNQDRTVRVTERIARETTLTPLAHLTCVGASVAALRQVVGLYAASGVRNIL
ALRGDPPGDPGGEWTAHPEGLNHATDLVELVRTLGDFTIGVAAFPDVHPASPSFEHDVDV
MVRKADAGASFAITQMVFDADSYLRLRDAVAARRDLPITPGLMPVTNFKQVARMSELMGT
PLPQAVVQRLQAVSDDPAATREVGVQIATELADRMLSEGAPGLHFITMNRSTATLEVYRN
LDLGARTAASRA
>A0A5R9FP99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces montanus|TrEMBL
MALGSASTRTDRARTVRDMLATGKTTYSFEFWAPKTEKGERNLWNSLRRIEAVAPSFVSV
TYGAGGSTRAGTVKATEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWIPHPQGLTYAADLVRLIKEAGDFCVGVAAFPEMHPRSDDWDRDVVHFVD
KCRAGADYAITQMFFHPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PDALKERLLTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTASLEIYENLG
LHHSQQA
>A0A0Q4H765|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylophilus sp. Leaf220|TrEMBL
MTASPESTSSVDAGPAALPVSFEFFPTKTPEGAVKLRAVRQALYARGPEFCSVTYGAGGS
TQEGTFTTVREILAEGVDAASHFSCVGATRASVRAELAELAAMGVKRIVALRGDLPSGYG
AGGEFSYASDLVAFIRAETGSAFHIEVAAYPEVHPQARSPQADLQAYAAKVRAGADAAIT
QYFYSADAYFRFLDDTRALGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQAF
GDDTASIRAFGLDVVTGLCERLRAGGAPALHFYTMNQSAATLALLDRLLPAA
>A0A6J4MRU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Nocardioidaceae bacterium|TrEMBL
AQQTARRAPQQPGPRRPLRGAADAHRGAEGARAPADRPHRDGDSVPRQGLGRHPRPVRAA
GQAGLHGRPAPRGADGPRPQSARRDRRPADDRRRPLRVRPRGGQDAAGGAVRRRAGAAGG
PDRAGTAVRGGRHHRLPRDPPVAERRRRRAGDVGQAPPRHEHREQPRLRPGCHGRVAAAD
ADARDHAAGVARDPGTRRARQAARDGDEDRRRRLHEVPHQAQARDAAAGGAGRVHRGALP
RGLRARALTARRRCRRAPRLHLQPGRRDRAVAHDAARADAGHRPSTL
>A0A2D1IR54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. LoGeW2-3|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A5R9FRZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces montanus|TrEMBL
MGDAGLRALLRSVRYEVLPAKSTEDKVLAHVPRDVVVTVTASPVKGLEPTLDLVTRLAAH
GYRVVPHVPARLLRDEGHVKDVVDRVREAGVDDIFVPAGDADPPAGVYDGALPVLRSLSE
LGSPFSRVGIAGYPESHPLIHDDVTIQSMWDKREHATYIVSNLCFDPRELGQWIARIRRR
DVPLPVHVGVAGPVQRAKLLSMAAKIGVGESTRFLTKHASWFLRFAAPGGYSPERLLARA
EEALTAPSAGVAGLHLFTFNQIAETERWRCALLDRLGG
>N8NXS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bohemicus ANC 3994|TrEMBL
MTKRIPVSFEFFPTKTDVGAEKLRVVHQELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYASDLVA
FIREHSGDHFHIEVAAYPEMHPQAESFDQDIQNFITKARAGANSALTQFFFNPDAYFYFV
DRLQKEGVDLPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNQTEPNRQLVLDLGLA
>A0A1G1P7H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium RIFCSPHIGHO2_02_FULL_52_10|TrEMBL
MNKISELFRTKKRTFSFELFPPKTEQGYAGLLDTIAALAKLHPDFISCTYGAGGGNRGKT
LDVVEHIQNKHRVTGLAHLTCVLHTKDEIRNILKEIKARGINNVLALRGDPPQDRPDWKP
GAENFKYSSELCAFIREHFADYFTIGVAGFPEGHVLCPDREQDAKYLKIKIDNGADFVIT
QLFFNNQDYFDYVARLKRLGVSARVIPGILPITNYPSLLKFCDLCGATVTDEIKRLFAPI
QDDKEAILQAGIQFAVKQCRELLNGGAPGLHFYCLNKLEPTATILRKLEK
>A0A1F1A588|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC061E03|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQPNFEGN
>A6DQ44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaera araneosa HTCC2155|TrEMBL
MTQDDDQLNINFNESNPFQDALAGGKFSVVVEVAPPLEGEGDSDNMFSLEKIAEECSRHE
EIVGIAVNDRIQGPTHIPAWKLAQRLSKISTKPAISHISGQGHDQESFEEEVAAASSAGI
NNLLLISGTLQEGEEKYFESTEQLRNCTAKHENINTGAAVNPFKYSVNSSFAQYLKMIQK
ISSGAKFITTQAGLDMRKYDELLRFCTHREITVPLIARLNLISHDCLPMITDLQMEPGVP
LSREISSLVLRELNEAQDHSSFMNIQLRRLCLQINACALMGYSGVQIKGIKNAVELHQVM
IRMRACMEEIISLEQFYQEWDALNQSVSFSPGSSIVQSLPNQDLKSSNHAQTGTYYIYKK
SELRPVDESLSSDNTDDLIYADFNHPSEFEVFRTKLAKKLNLDEKDGSIARLLKKTITGI
SDDSPADLAKTQFTDLSACPKKLIHGCCGGTRSDDLCEDGKSSCIHLARIGMAASLNQLD
LLEQPSD
>A0A2M7MXA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium CG_4_10_14_3_um_filter_63_21|TrEMBL
MNDRTFSIEFFPPKTPEGVEKLRHARRQLAQLHPKFFSVTFGAGGSTRERTLETVLEIQG
EGLAAAPHLSCVGSTHENIREILETYRANGIRHIVALRGDLPSGMADPGEFRHANELVSF
IRQETGDWFEIEVAAYPETHPQARNYREDLENFKRKVEAGANAAITQYFFNADAYFNFVD
DCAELGVTLPIVPGIMPISNYSQLSRFSAMCGADIPRWLARKLESYCDDTASIKAFGLDF
ITGLCERLIEGGAPGLHFYTLNQAGLTTTLWQRLGLN
>A0A8C4MI07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Equus asinus asinus|TrEMBL
MVNEPRGNGGPIPRSDGSSSGSESSRDSSRCSTPGLDPERHERLREKMRRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETVLHMTCCRQSREEITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVKH
IRSEFGDYFDVCVAGYPKGHPDSGSLEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDGAIRNYGIDQ
AVSLCQQLLASGLVPGLHFYTLNREVATTEVLKRLGMWVEDPRRPLPWALSAHPKRREED
VRPIFWATRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTFELLNRPAPNEREMEAP
>A0A7X6WKM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MATWLYQHGVPIGVCYEELCLSKPALIQTVHREYYAAGARLIETNTFGANRTALSRYGLE
HLSYRINWKAAVIAREAVGEDAWVVGSISSITGGGIRDVKMAGYAAQFAEQAEALLAGGV
DGIILETFLDLEELLLALTTLRPLTALPIIAQLACLEVGPTRDGYSLAEAFTCLDRAGAD
VVGLNCRLGPAEMLRSLEQTVVPEGVLLSIFPNAGRLGVTDGEYAYTSSPEYLAEKARHF
REQGVRLIGGCCGTTPAHIQAVAEALAGLAPLPRVNPDRGVLTDEKAEQTDAPGDSVRLI
HLPGTAGLVQPSRPLTTLSSPPALTIVDKVRQGPTVIVEFDPPKDLEVEGYLRGAANLQD
AGADAITMADNSLAQTRMSNMALGAIVKQKLGIDPLIHLTCRDRNLIGQQSHLMGLHALG
LHQVLVITGDPARFGDLPGASSVFDVNSFDLIRMVKQLNEGISFSGNRLQQRARFVVGAA
FNPHVPKFDNALRRLEKKIEAGADYIMTQPVYDVATIELIYESTKHLNIPIFIGIMPLTS
SRNAEFLHNEVPGIRLTDAARERMRRYTGEAARQEGVAMAKELVEAAQQYFQGIYLITPF
AYHEMTAELTRFAKKK
>A0A3N2JK73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. PhB143|TrEMBL
MTVTVGTGHRPTVSFELMPPRNPDAAPKFWETARRLVAVRPDFVSVTYGAAGNDRTTART
VVGRLLRDTPVLPIAHLTCVGASEEDVTDVIGDFLDEGVRSFLALRGDPPKDQPDWQPAA
DGVGSSIELVDLLRRVEAERCAASASTALRGAARPLTIAVATFPEGNRDAGTTREQEVAR
LLQKQQAGADFAITQLFYEAAAYTGFVEQARDAGVTIPILAGILPMTEPRRLRRVEELMG
VPAPRTIVAELEAAADDDAARHALGVRRSVELAQEVLDAGAPGIHVYTFNKHEAALDLLE
GVHLGGGSTAPDLASGPWVIGRTTPAPDTAEGLRR
>A0A0E0P313|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryza rufipogon|TrEMBL
MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPIEKIDDALTTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQNTEGATPEAYSNDLAYLK
QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNL
GLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFVNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGERSDSTNVGWGGPGGYVYQKAYLEFFCSKEKLD
QLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWK
DEAFEIWSKGWACLFPEGDSSREILDKVQKSYYLVSLVDNDYINGDLFAAFKEI
>A0A2E5CH94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MSANLFNLKDDDFIFTAETTPSVSTNLSENVQKISSLIGVADAVNITDAPNCKTKLSSLV
VAGEIKKNGLDVILQITGRDRNSIALESEILGASSLGIDKILCLSGDRPPEDGPMAVNEM
NSSNLIELLSKMSAGKLLDGTEIREYKKIYSGCADSIHDHYVRDTHSSFFVEKVRMGVDF
VQTQYCYDLDLCKKYSEFILENNLSDKTKFIVGLGPLKSAKQASWMRENLYGVKIPDSII
LRLEEASSPIDEGKKICEEIIQDLIDLKGISGVHLMGPNCEDQCAELIKHFR
>C6L995|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marvinbryantia formatexigens DSM 14469|TrEMBL
MKITELFERGEFVVSAEVGPPKGFHIENILEEAKTYLSGITAVNVTDNQSSVMRLGSLAV
CKALKDEGLNPIFQLTCRDRNRIALQSDLLSAAMFGIDNVLCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVTKLESGEDLGGNPLIGEPPKFAKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGVHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKVPALLEQAGL
>A0A5D3AMA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus floricola|TrEMBL
MPPLTSLIAAHDGPFHNYEFFPPRTDAGLVNLLERIRRLISAPLQRPLAVSITWGAGGST
AEKSLELAEQVVKMGVEVVLHLTCTNMAKEKVDLALQRCKDLGIQNILALRGDAPRSEEY
AVTPNVPDFFQHADDLVRYIRAEHGAYFCIGVAGYPTAHPDSETDEDEMKWLKVKCDAGA
DFIVTQLFYDVDGFLAWVKECRAQGIKQTIIPGIMPIQSFGSFRRLVNLTKCPVPSSITS
DLQPISSDDAAVKQYGATLATKMVKQILDSGEIHGVHFCTLNLEKSVRTILDNLDWVERD
QRDSVSSLDRNRFIESDEDARPSGIPINGKTRSYSNSASLSISPSDASHLAQLGLTSALP
PKSQTHSTATGAPSGPGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKE
WGVPTTTSDLSTLFTSYLQNSPATPTTPFCDLPLSPESQTILPHLLKLNSADKCFWTVGS
QPAVDAAKSEDSVVGWGPRGGYVFQKAFVEFFVRPEEVEGLVKKVDELGKSMITLYASNK
KGDFKTNTDPSAVNAVTWGVFPGQEIVQSTIIEQESFFAWKEEAFDIWTEWAELYPRQSA
ARKLLEGVSGEWWLVSLIHHDYKKEDALWKFLLDA
>A0A553Y655|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. YGAH215|TrEMBL
MTKPTFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRGRTLDIVQALCA
RGDTDIAPHMSCIGDDKSQIAELLDLYKSLGITRLVALRGDLPSGQVSMGELPFALDLVK
FIREYSGDHFRIEVAAYPEMHPQARSFEFDVDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTVAQPLVAGIMPITNSSNLVRFADSCGADIPRYVRKRLADFGDDRTAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVEALGLIA
>X0ZXB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MAKRPAYSNLVKTMREGKFLFTGELEPKKMVDLSSILHSAEEMKKTGKIVAANVTDGPQG
DAYTCSMVPCYLVQEKVGLEAIWQMTVRDRNRIALFGDILGGAILGLKNMLALTGDHSAL
GDHQNARAVYDLDSTQLIDLVSKMVD
>X1V4X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKLINLWKTSQKPTLSFELFPARSPKAAERLEKAIDNLADLEPNFVSVTFGAGGSTRKGS
YNLIKKLIYEKGLEVLGYFACFGLSPGEITSVLDSYQALGLENILIVRGDEPREMDDWEP
HPDSFLYASDLMAYVKPRYDFCFGCAGYPEGHIDANSKEADLEFLKLKVDNGAE
>X1F4N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSLQPLLEAGKFVVTAEVGPLKGTDTTETEEAAELLLGKVDATNVTDQQSSVMRLGSLAI
CHLLKEKGLDPVFQLTCRDRNRLALQSDLLSAYILGIKNVLAITGDLPSLGDHPQAKPVY
DLDSVQLLWAIKRLNEGYDMIGNELKGKPDFFPGAVVNPGADTEAAFELQLISMEKKIMA
GARFFQTQAVYDMDAFARFMKRAEGFNTPILAGVIPLKSAGMARFMNKNVAGVFVPEDLI
NKMAEAEDKARTGIDIAINIIQELKDICQGVHIMAIGWEKRVPEIVELAGLLPRPVL
>X1JX76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKTKSNLERVLEAGHFAVTGEIGPPAGADPEVVRRKAKMLKGNIDAFNVTDGQTAVVRMS
SWAACLIGKEEGLDPIVQMTCRDRNR
>A0A0F8X1I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
PCSERLISLIRVYIPNWIMALFTPGRRWQPPFLPFKKEKFSKRLLRKIERWIKGPLFGCR
MCGNCLLQETAFICPMECPKGLRNGPCGGSTAEKCYVDETRPCIWYKIYERAYNMGREEI
LLEELPPLDWDKVGTETWGDVVRSIRKFGSRAFFKSLFTRNKEKKANAWEGVFKPVRQPE
WWQGDSEYHAPAYDEPISELERKLREGKFVVTAEVAPPLGTATGKLSRDIEMVRDHVAAV
NFTDSASASPRMSSMACCKVAAELNADPVLQIAARDKTRSGLQSDIIGANLMGVRNVLCI
TGDNARIGPTPTSNTNILDVDAIQMLWMLRRMRDDNIYLDGRKMKSSP
>A0A0F9CJ16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
SRAITQYFYNPDSYFYYLDQCGKAGIDQPIIPGIMPIINYQNLVRFSDSCGADIPRWIRQ
RLQQYGNDTESIKAFGLEVVTNLCEKLLAGGAPGLHFYTMNQVEANTALCRNLGFTEELG
>X1DUU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MATPFREILKTKGFVVTAEVGPVKGSNVSKAIEHIELLKDKVDGLNVTDNQSSVMRYPSL
GICLLIKEHGGEPVFQVTCRDRNRLAIQADLLFAYSRGISNVLCLTGDSIDVGDHKEAKQ
VFDLDSVQLIHLVHTLNSGKINILGTVSLAVITLDAEPDSV
>X1KVV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MTGELGPPQSADPEVVRRKARILKDYVDAFNVTDGQTAMVRMPSWAACLIGKEEGLDPVV
QMTCRDRNRIALQMDILGVAGLGINNVLCLTGDHQKFGNHPEAKGVFDLDSIQFLKVVKD
MRD
>X1RKG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
METIMQICSRDRNRLALQGDILSTYFLGIKNLLVVPGEEIVYGDHIDTKPIVDIDELTLL
RAIKGLQNGVDMAGMELKGSPKFVTGCSIKPAKNEIALEAELELAQKKVREGAQFIVTPP
VFNIPAFTYFMEKAKVLGVPVIATVFLLKSVGVARYIATNVPGPPIPPEMITRIRKAPDR
IHECITIAAELVTTLKGLCQGVQIVTMGWENRLPAILDAANI
>A0A3M8DAQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus fluminis|TrEMBL
MANKPNLKEYVKDHLIVGDGAMATQLYQLGVPVGVSYEELCLSNPQLVQSVHAAYYRAGA
RLIETNTFSANRDSLTRFGLESKVTRINRAAVTIARNAVGEDAYVIGGIGSIIAGRVRSQ
QLDEYRDQFEEQATALLHAGADGILLETFLDLDELRLAVEVIRPLTELPIIAQLATLEVG
RTRDGYTLTEAFAQLQQSGADIVGLNCRLGPAEVIRSFETTVTPDDILLSAFPNAGRLGL
SDGEYAYKSSPDYFAQSALLLRKQGVRIIGGCCGTTPDHIRAMAEALAELPPVERFNPSP
ATEPRIEIGTVAPRRTPHIVDKVKQQHTIIVEFDPPKDLDAEGFLHGCCELHNAGADAVT
LADNSLANVRMSNMALGAMMKSQYGLEPLLHLACRDRNLIGQQSHLMGLHALGIDQVLVV
TGDPSRFGDLPGASSVFDVTSFDLIRMIKQLNEGISFSGRPLKQKANFLVGAAFNPHVRQ
IEAAVQRLERKVEAGADYIMTQPVYDAETIKLIYDATKHIDIPIFIGIMPLTSYRNAQFL
HNEVPGIKLSDMALERMKNVEGEAARQEGIQMAKELLDVAMSYFKGIYLITPFNYYQMTV
ELTQYVRKQALLQPTR
>A0A7K3CW72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID337|TrEMBL
MTALRALIDQDTPSFSFEFFPPKSDAGARTLWKAIRRIETLAPTFVSVTYGAGGSSRDRT
VEVTKRIAAETTLRPVAHLTAIGHSVAELRHIIGQYADAGVRDVLAVRGDPPGDPGAPWT
PHPDGFTHAHELVRLVKESGDFSVGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQ
MFFDVEDYLRLRDKVTAAGCTTPIIPEIMPATDVRQISRFAQLSGAAFPEHLAHRLEAAR
HQPAEGHHIGVEHATAMAQRLLAEGAPGLHYITLNRSTATLEIHRNITDARSTPHDLAAH
H
>A0A2R5G8R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hondaea fermentalgiana|TrEMBL
MAPAPLISDLVADKGDEPWIAFEYYPPKTEKGVATLYKRLESMKELGPLYADFTWGAGGS
TSDLTLELAVTAQDRFGLVSNMHLTCTNMPREKIDIALEESEKAGIRNILALRGDPPAGQ
EDFKAVDTGFSCALDLVRYIREKTGDLFSISVAGYPEGHPTRIKKVIAGQSLSPSEQARS
VRMDDGSVHVCSDVDFHEEMLYLKQKVDAGAQMIVTQMFYDVQVFLDFVEACKRYEINVP
VIPGIMCITSYGGYKRMCAFCKTRVTPQMYEELEAIKDDEAAVSRFAVKFGVETCQKLLD
SGVKGLHFYTLNLDKVVTAVLEGLGMLKSEEGEKIAATA
>X1UR28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
KEIIPAKDWSTSRDGGPRKLNIREPHHKKAATSKEKKTEEAKTPVSSAKANSNLRRILDG
GEFAVTGELGPPKGADAEVIKKKALYFKDSVDAVNITDNQTAIVRMSSIAAGVILSQMDI
EPVVQMVCRDRNRLAIQSDILGAAALGIRNVLCLSGDHQKFGNHPQAKNVYDLDAIGLIQ
VLKSMRDEKKFLSGDSLTVSPQLYIGAVENPYADPYEFRAIRLAKKIEAGCDFIQTQGVF
NVKKFRDWMKIVRDSGLDGKVHILAGVIPIRANSA
>X0WFE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKLTEIWKKSTNPTVSFELYPPRTIKAAEKLEKTIDLLAALKPDFASVTFGAGGSTREGS
YQLLDNLKNQKELEVVGYFAGYGLAPKEITSVLDSYQELGLGNILVVRGDIPHDPEGFTP
HPDSFAHASSLLEFIRPKYDFCMGVAAYPESHIEAESREKDLEYLKLKVDLGADYIITNY
CYDNKYYFEFVERCQEKGITLPIIPGVMPIYSPKMMENLAKLCGATITDEIRQDLAD
>A0A0F9UZD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSNEPVSNLQRDLDSGEFVVTAEIGPPKGTNIAPVIHEAEEFLKGKVSAVNVTDIQTAVM
RGSSMVGAKLLFDAGIEPVLQMVTRDRNRLALQSDLLAAHIFGIRNVLCLTGDHVTMGDH
PQAMPVYDLDSVSLLDAMCKLEAGTDLGADMKGKANELDGVPTFFKGCCVTPCADEVDPQ
VIKLEKKVEAGAQFVQTQAVYEPKVFETFMKKVEHIKVPILVGIVMLKTAGMAKYMNRGV
PGVVVPDAIIQRMTDCEKPDREKVSIEICGELVSTMKDMCQGAHLMTLGWDHCVPGIIQA
AGLA
>A0A8H5KG28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium pseudoanthophilum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFEATLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLSSDSSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGVKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A0M8YJ76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL F-6491|TrEMBL
MALGTASVRSDRARTVRDILASGGTSYSFEFYAPRTEKGEQSLWKAMRRVEAVGPSFVSV
TYGAGGTTRGGTVKATQKIASDSTLTPVAHLTAVDQSVAELRNILGQYADAGIRNMLAVR
GDPPGDPLGEWIEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVVKAGCETPIIPEVMPVVNVKTLDRLPQLSNAAF
PARVKDRILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A3M7I785|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGIRNILALRGDPPRSDE
YNDPNNPLSEQDDSNKDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLVEKTAAGADFIMTQLFFDVEAYNNYEKRLRSHESGGFHFYTLNLEKVVTQILERT
GLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSSNRNSMPQNRVVVS
RRSSTSSSKTQAYEAPEDEAGVPPVNSRANTLAISEGQGSAGREATWDDFPNGRWGDVRS
PAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLKGEIEAMPWSEEPLQPETL
TIKKELLSLINKGWWTVASQPAVNGVRSTDPIYGWGPKNGFVFQKPFVELFLPSADWQRL
KPILQSDDQVTYYAGNAAGEFQSSDENSVNPVTWGTFAGKEIITPTIIEADSFKAWLEEA
FGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDALIAA
>A0A0T1SHX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Root1304|TrEMBL
MALGTASVRSDRARTVREILASGGTSYSFEFYAPRTEKGEQVLWNAMRRVEAVGPSFVSV
TYGAGGTTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNVLGQYADAGIRNMLALR
GDPAGDPLGDWIEHPEGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDADIRHFVD
KCRAGADYAITQMFFDPEAYLRLRDSVAKAGCETPIIPEVMPVVNVKTLDRLPQLSNAAF
PPDVKDRILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A5N6L4L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carpinus fangiana|TrEMBL
MTTSCVCALLNTIEGTTKFEWSTRYREPQILGRNYHLGLCNSWTGVVDYQANSNRRWRGR
SATAVSSSLPTFFANRPSDAYALTLDSPIARHLACFLLLSTHLVPVLDAARRYTALGPYC
LLPARLVFDHAHCGQAKREREARSYGLLLRVLPTQDCSGKSCRGTKAPPTTLLILARAYK
TFMIVCWTLPIAGFLHRPSARAYINIGIDRMHGLGPTFIDVTWGAGGRLSNLTCDMVKVA
QNVYGLETCMHLTCTDMETTKIDNALKEAYNAGCTNILALRGDPPREKEKWQATEGGFRY
ARDLVKYIRKEYGDHFDIAVAGYPEGCEDQDDPDLLIDHLKEKVDAGASSVITQMCYDAD
IFINWMEKVRAKGITVPLIPGIMPIHTHAAFMRRANWTQCHIPDHWKEALDPVKNDDVAV
REIGAELVADFCRRVVTAGVKHLHFYTMNLAQATRMVLEQLDLVPSEETPVEKPLPWRPS
LGLKRRDENVRPIFWRNRNRSYVERTQDWDEFPNGRWGDSRSPAFGELDSYNIGLKGTNE
NNRKVWGEPKTVAELSTLFVRYMQGKLESLPWSESAITGEADVLRNDLVDLNRRGLFTIN
SQPPVNGAKSSHPVYGWGPRNGYVYQKAYLEVLISPEVFGELIDRIEDDQDLTYYAVNKH
GELRTNAPSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEFFRLGEDWAHCYDADSPS
RNLIEGIMNDWYLVNIVHNDFHSTRGIFPLFNGMELTAMDQPYTSQAAPDAPLTNGNHTN
GTAELHN
>A0A3M7F5H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMSYDAEIFIEWAKKVRAAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAELFVKYMSGKVETLPWSEQPISPESNVL
TNDLVNLNSRGLLTINSQPAVDGMKSSHPVYGWGPNNGYVYQKAYLEVLISPSLITELIR
RMDANADITYYAVNNSGELKTNAPQDGGPNAVTWGVFPGKEIVQPTIVETISFLAWRDEF
YHLGSEWAKCYDEGSRSKNLIKEITESWYLVNIVDNDFRNERGIFPLFDGLKVQGVESTA
AAVNGVAPHVNGDAQHADVEKKQGAQKPEVNGVPDKNNAVNHADGPAVNGQVKN
>A0A2X0JWY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptacidiphilus pinicola|TrEMBL
MALGTPSTRPDRAVSIRDLLASGAKSYSFEFMPPRSPEAEAGLWKAIRRLEALAPTFVCV
TYGAGGSTRGRTINITGRIAAETTLTPVAHLTAVDHTVAELRNILGCYADQGVRNVLALR
GDPPGDPLGEWVPHAQGVNYASELVELIKESGDFCVGVAAFPERHPRSTDWDEDIRHFVT
KVRAGADYAITQMFFDVDFYLRFRDRVGAAGCDVPIIPEIMPVTSVRSLHRIPTLSTAWF
PPQLRDRMLAHEDDPKAVRAIGIEYATEMCRRLLDEGTPGLHFMTMNFSTVTSEIYQNLG
LTPQS
>A0A3M7GYG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGIRNILALRGDPPRSDE
YNDPNNPLSEQDDSNKDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLVEKTAAGADFIMTQLFFDVEAYNDYEKRLRSHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLRRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTL
NLEKVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSS
NRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPVNSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLQGEIEA
MPWSEEPLQPETLTIKKELLTLINKGWWTVASQPAVNGVRSNDPIYGWGPKNGFVFQKPF
VELFLPSADWQRLKPILQSDDQVTYYAGNAAGDFQSSDENSVNPVTWGTFAGKEIITPTI
IEGDSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDA
LIAA
>A0A154VDP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira sp. MCCC 1A02898|TrEMBL
MTVPEINAVRKHLKVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGTTRDRT
HGSVTRIQGETGIPAAAHLTCVGHTKEEIDQIARSYWNEGIRSIVALRGDLPDAGDKYEP
TPGGYAYAVDLVAGLKEIADFDISVSAYPETHPDAPSSDFEIDYLKRKIDAGANRAITQF
FFDNETYLRFRDKCVAAGIEAPIVPGILPVTNFASLLKFADMCGASVPQRLHWRFEGLDE
DPDTRRMVAFHEAISQVEGLISEGVTDFHFYTLNRAELTYAICHALGIRGTEQVAA
>A0A4S2F489|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriaceae bacterium|TrEMBL
MATKTVSQIFATQKLPVSFEIFPPKGDLSQEEAQQVASQLAPLDPAFISVTYSAGGSGNS
SRTLEVARLIQRDYDVSTVAHLTCQGLTRQSLAKKSARLKEAGIKNVLALRGDPNPEAAP
GDFEYASDMIPQLVEGGFCVGAAAYPEGHISCLDPDIDVAYLRGKQDAGASFLVTQLFFD
NQLAYRFRERCHKAGITVPITFGVMPFLSKSQVSRMIFMCGASLPSAVVKLLARYEDDPE
SLRAAGIEYACAQLQDLATHGVDGLHIYTMNRPQVAAAAVAAIREVL
>A0A238JS42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actibacterium lipolyticum|TrEMBL
MSAPRISFEFFPPQSLEASFRLWDTVQTLAPLNPGFVSVTYGAGGTTRKLTHEAVATIHK
NYGLNVAAHLTCVDATREETMEIVNAYAEAGVSEIVALRGDPPKGQGGFTPNPDGFANSC
ELVEALAETGKFNIRVGAYPDPHPEANGAGDDVKWLKRKIDAGASSAITQFFFEADTFFR
FRDACEKEGIDAPIIPGILPIENWAGVRKFAARCGAHIPTWLDEAFEAAKRDGREEILST
AIATELCSDLIDGGVEDLHFYTLNKPHLTRDICHALGAQPDVTLEDVA
>K0G451|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus suis H91-0380|TrEMBL
MSYAKEIDHLNQSVADLNGQINVSFEFFPPKNEKIETMLWDSIHRLKALKPKFVSVTYGA
NSGERTRTHSIVKNIQQETGILAAPHLTGIDASPDELRTIAQDYWDNGIRNIVALRGDEP
AGYAKKPFYAADLVRLLKEVADFDISVAAYPEVHPEAKSTQADLIYLKQKIEAGANRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKVTNVRIPSWMQKMYQGL
EDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A4Q0IY65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Isolate-013|TrEMBL
RDETEYALIDLNFLGVHDLLLLQGDAKGPDKSTDPSLVNLHATDLQAQVNDFNRGIYADG
EPFEANATPFSYGMACYPEKHEAAPNMESDLRYARMKVDNGASYLVTQMFFDNQKYYDFV
ARCRAEGIT
>U4QI63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus CIRM-BIA 953|TrEMBL
MSLTALFKNKTVFSLEVVPPKKDSPKEAILPTLQQLQSINPDFISVTSGAGGSDHYTGTV
QIADLIQNQLNIPAVAHVPGLYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDF
NHANDLVAFVHQNRPDFSIASACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDN
QAFYDFQEKAEIAGIHVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSKEA
MREAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTMNYT
GTEVPGFWEH
>A0A1H5NBA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas migulae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A504KPK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B1-1-5|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEVRLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFADMGVKRFVALRGDPAAGVGA
SYHPHPDGYANGAELVGALKNAGDFDISVSAYPEKHPESPDFATDIDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHETEAA
GSAAA
>A0A3M7FAG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGIRNILALRGDPPRSDE
YNDPNNPLSEQDDSNKDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLVEKTAAGADFIMTQLFFDVEAYNNYEKRLRSHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLSRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTL
NLEKVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSS
NRNSMPQNRVVVSRKSSTSSSKTQAYEAPEDEAGVPPVNSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFHRHLKGEIEA
MPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSTDPIYGWGPKNGFVFQKPF
VELFLPSADWQRLKPILQSDDQVTYYAGNAAGDFQSSDENSVNPVTWGTFAGKEIITPTI
IEADSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDA
LIAA
>A0A2N8ZG02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio tapetis subsp. tapetis|TrEMBL
MGYTHASHIDALNQNIAELSDDINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDANREELINIADDYWANGIQSIVALRGD
IPPGGGVPDMYASDLVELLKSRHDFDISVAAFPEVHPEARSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDAEIIPGILPVSNFKQASRFAGMNNVKIPGWMKQQFE
GLDDDPLTRQIVGSSQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRP
>A0A0S7WS10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium DG_58|TrEMBL
MKSGSKLERILEAGHFAVTAELGPPMDCNAEEVIKKAKLLKGVADGYNITDNQTAVVRLS
SIAAAVLIMAEGLEPVMQMTCRDRNRLAIQSDILGAAALGIRNCLCIAGDHQSFGAAGRL
KGHPGAKNVYDVDSIQLLAILKGMRDDGQQQGGDPIEVRPRLLIGAAWTPLGDPVEIRPL
RLKKKVDAGADFIQTQGVYDVERFREQMKVVHDMGLHERTAILAGIIVPRNLGMLKYMDS
SVAGVSVPEALMKRMAKARAAAGKDKKQASKNQAAEGIKISVELIEQVREIPGVKGVHIQ
AIEWERRVPEILEKAGLLPRPTVAGEETTNGPKSEDHGGGG
>A0A7C7XCP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lambdaproteobacteria bacterium|TrEMBL
MSRHRKHQPSPLYRLRHETPMKLIDLYRRKSFVFSIEVFPAKTAEGMETLKQTLGTFAKF
RPDYFSVTYGAGGGTRENTHALATHLQNKLGIETMAHLTCVSHTGQEIEVVLRRLEKSGI
ENVMALRGDPPQGSTEFRRPENAYNYACELVAAIQKRGGFGIGAAGYPEGHIENPDQDAD
RHFLVEKINAGVDFIATQFFLDNSFFLRWRDQLAADGVSVPLVPGLLVPTSLKQLTRMAD
FCGISIPNKLRIQLETHHTDPEAMKQIGLEHTSCQLENLLREGIPGIHLYALNKLATVQH
LAPLLPYSSKNLLAPCAA
>A0A357BZV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MEQNTKLSRLLSKQVVIGDGAMGTMLYSKGVFVNTCFDELNITRPGLIKDIHEQYVSAGA
DFIETNTFGANEYKLAKFGLFDKVEQINASAVKIAKEAAGGNALVAGAIGPLGIEGSAKL
SEKQIIEIFERQIKSLADAGADFLLFETFGNLAELLLAVRAAGSVCGLEIVAQLSVNENK
ETLFGDRLDEAIIELCRCSHVAAAGLNCLLGPAAMLDCLDVLKTVATKPISIQPNAGLPQ
TVDGRTLYMSTPEYMAEYAKRFYQRGARIIGGCCGSTPEHIRQIAQAVKSIDKSERPPAI
EIRQVEKAVRQIPVELKDKSQFGAKLAAGQKIITIEISPPKGADLSGLIEKVNLCKQAGV
DAVNIPDGPRASSRISAMITAIKLQQACGIETLLHFCCRDRNIIAMQSDLLGIHTIGLRN
VLIITGDPPKLGEYPNATGVFDLDSTALTKVVSDLNCGLDIAGNGFTPKTALVVGVGANP
VAAEMKRELERFKKKIAAGAEFAITQPVFDSRSLFDFLDAADCRIPVIAGIWPFTSFKNA
EFMANEVPGVVVPKNILDRMATAKDQLQSKKLGVQIAKELMEQIKDRVAGFAISAPFGNV
KMALAAADKFDIQLG
>A0A6N8A2C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium sp. RKSG952|TrEMBL
MTDTRLTPNGRLAASTEMSPKQVVEKSELLSFIPRGTRVYVTDLGNASEDMIVSAAKTLH
DRGLTPVPHMAARRYPSAEAFERRIKRLTQEAGVADVLVIAGEADKAGPLTSSVALLETG
LFDELGIKTIAVAGHPEGAPDIKPDVIKSFLLRKHEIAASSDARFFLVTQFGFDPVKVNQ
WLDDIASWGNKFPVHIGVAGPAKMTTLLKFAAFAGVENSLNFLKKRGGSVVSMLSGYDPD
TMVEPLEARLQTRPHSQLAQIHAYPFGGIQKTADWLTERGSWSFRNDQTSSLTA
>A0A8H7ENP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria burnsii|TrEMBL
MHISQKLAQAKEEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDDALRDAYNAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDDVDELIDHLKEKVDAGGTF
IVTQMFYDTDLFLDWVNKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTRCNIPKHWTEAL
EPVKNDDVEVREVGKHLVAEMCRKLIDAGITHLHFYTMNLAQATRMVLEELDLLPDPESP
LEKPLPWRPSLALNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPMSIRDLSELFVRYMEGKLESLPWSEQPITTEAGSIQDDLIN
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEHISEIITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVIHNDFHATRGIFPIFDGLEVKDMDKPLVNPSVDVPSANGEEATKVVNGGSHTN
GTNGEQAEPHKEENPSLIDAAKAAAVEVTNGMRSLAMSN
>A0A7G1H030|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dissulfurispira thermophila|TrEMBL
MSFKDALNSGKFVVTAEVGPPKGTDIKEMIHHIELLKGKVDALNVTDNQSAVMRICSMAV
CKIALEHGVEPILQMTCRDRNRIGLQSDLLGASILGIKNVLCMTGDHVLAGDHKQAKPVY
DVESVQLLRIVDSLNNGKDMAGNELKGATDFFQGAVVTPEANPIEPQLIKFEKKVRAGAK
FFQTQAIYDINKFKEFMSYARKFPVKILAGIVVLKSAGMANFINNNVPGIRVPQELIDEL
KAAGKEKALDTGLNIAARHIRQLKQENICDGVHIMAIGMEDKVPIIMERAGLI
>A0A2E0ZHE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MPLFTPGRRWQPPYYPFKKESADRRFLAFVERVTKGPLFGCRMCGNCLLQETAFICPMEC
PKGARNGPCGGSTEEHCYVDETRPCIWYEIYERAFKMGREEMLLEVLPPLDWNKVGTETW
GDVARQVKDVGTKKVLIDLVARDKETRAETWDAVFRPVRQPDWWEGDAEYHPPAYDEPVS
ELERRLRAGEFVVTAEVAPPMSAATGKMGRNVEMVRPYVAAVNFTDCPSATPRMSSIACS
KLALEQDAEPVLQIAARDRTRTGLQAEVLGASAMGIRNILCLSGDSANMGPSPKGRMDVI
DIDSIQMLWILRRMRDEGKYLDGRSIKFRPQYFLGAAGSPFASRPEFQAIREHKKVNAGA
QFFQTNLVYDPDGLEAWLNELAKRDILDKVYILIGITPLKTLKMAQYMHHDVPGVVIPKR
ILNRLEAAGDGVEEEGVQIALELIEAIKGKHGVNGIHLMAVGWEEIVPRIVTEAGLAQPE
LSVAEPWLNGR
>A0A3A4VZV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MKRDAFLNKLREGKPLVADGAMGTLLHDRGVGFESCFDELNLTNPALVASIHQEYIKAGA
EVILTNTFGANRYKLERCGLEELLDEINQTGVDLARRIIRASFKDVLIAGDVGPLGVRLA
PFGRVQAEQAREAFREQIQALVDAGCDLIVIETMTDLYEIREAIAAAREVDPDIPVIASM
TFTRDDRTLLGDDPQKVAAKIFSYGADVIGINCSGGPNQLLRLLKKMKKEIPDGFFWVKP
NAGWPEQISGRIFYPASAEYFGEYALAFWQAGARVIGGCCGTTPAHIQSIRQAIDSQEVN
SIANGITLEFIEEESIEEEISEPSKFAQKLGNGEFVYSVEMQPPRGLATKKVIAGASMLV
DSGADAINVADSPMARMRMSPWAVCSLLQYKVNVETILHFPTRGRNLLRVQGDLLAAHAL
GVRNVFVIMGDPTAIGDYPEAMDNFDLAPSGLVKLIKQRFNQGIDQSGSDIGQPTNFYVG
CALNLAATDPEREMDILKRKIHSGADFIITQPIYEADLIPSFLKAYQASYEELRIPLIIG
IMPLVSARHAAFLHQEVPGISIPDVIHQRMQTAEENGTGPQEGIRIAIELIRKIRGLAQG
VYISPSFSRFDYVAEIIENSK
>A0A506QGV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea deleyi|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTHEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATREELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGSDLVSLLKEVGEFDISVAAYPEVHPEAKSAQADLINLKRKIEAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATLTNVRVPGWMHAMFA
GLDNDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAAAA
>A0A1E4ZV39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MKDVNFSYEFFPPGNLIGERRFWRSLGCIETMNPAFFSITYGALGTDQERSINTIENVVQ
ETDVPIAAHLTFEGSTRKEINRVARRLAKAGVDKIVALRGDARADADAAAQRGPCYQSVA
EFIAGLVEIYPFDISVACYPEVHPKALSVGADILELKGKCDAGANRAISQFFFDVDQFER
FRDNATAAGINVPIVAGILPIRDFHKMTVFAERCGTKVPQRLYDLFEPAKRNPQLAAQIA
QDEVESFIDRLISRDCSDFHIYTLNQPIELRQCAMSRQRSLAAPIAVSA
>A0A2N2IPN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-16|TrEMBL
MLVKDILDNNRFSFSFEFFPPKDEPGWENLFANISDLMPLKPAYVSVTYGAGGSTRDRTH
KLIVRIQQETNLTVVSHLTCVGSNRAETGEILRNYAASGVENILALRGDPPKGQTDFVHP
PDGFAYAADLVAFIKKNFPHMGVGVAGFPEGHPATPNRLLEMDYLKAKVDAGADYIVTQL
FFDNRDFYDFRDRCELSGITVPIIAGLMPITTKSGMVRMAELAAGARIPAALLRALDRAR
SDEQVEKVGVHWATEQV
>I9F2D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei CL02T12C06|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEAQINDFNKGVFVDGSPIKITGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVEKVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A101C637|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. JAH|TrEMBL
MKITDHIKNADGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEATPGGHASAMELVNQINNLGRGKYLHDEQICDDHNKFCIGVAGY
PEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVTKAREMGITVPIIPGIK
PIATKKHLKLLPQVFKIDLPEDLINAVESAKNNEAVKQIGVEWAISQCKELLDFGVPVLH
FYSMGKSDNIKKVAGELF
>A0A0K2RSN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Hiyo8|TrEMBL
MSPPSLIDTHPNLTGTAPVALSYELFPPRSPAAAESLWTTIGELEATDPDFVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPEELAEIIGELLDNGVRGILALRGDLPKD
SGQPVNGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSVEHDVEVLL
AKQRSGADFAITQVFFHTEQYADLISRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAPELIERLAAADSDAERRRIGVRATVDLANAALQAGAPGIHLYTFNEHACALDVLDKLA
LPGRPGPPAGSVPSPAAKNSSADQPTLLRTPLDTSICTYCPKEIP
>A0A2P1TIL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNQKKLVFSFEIFPPKATSSVKTIYETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTREYIDSIINELKENNIQNILALRGDIPKDKNIIGK
YNYAFELIRKIKENDNFGVAGACYPEGHIECESLEKDIKELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQQKNINVPIQAGIMPVVNKKQIERIIKISGATLPKKFMKILDKYEYDKEA
MRDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARRITESTKSIFNSINKDIAV
>A0A1G0ZXZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium RIFOXYC12_FULL_60_16|TrEMBL
MTPPSGFLDRIRQRPLIFDGAMGTMIYQRGVFLNACYDELCLTRADLIRGIHRDYAEAGA
EVLETNTFGANRIKLAPYGLIDQVAAINRAGVRLAREEAGTDRAVAGSVGPCLLPGTPLS
DANRPDIEAAFREQVGALAAAGVDLIILETFHDLPELQLAARIAREAGQTVLASYMVRDT
TGSESHPEEIMAHALDADPNVDLIGLNCGVGPAQMFHPVRRVLAVTRKPVVAIPNAGGAS
EVGGRHLYLNSPEYFTEFAKRFIELGVRGVGGCCGTTPDHIRMAVRAIRTMSGVKTFVGV
ADRARPESVARPPVETIPFAKRSAFAAKLAAGQRVTSVEMLPPRTVGGLPKFLAGVERCR
DRGVDVINLPDGPRASARLSVLVTAMILQRETRMECVPHYCCRDRNLIAMQADLLGGWAG
GLVNWLFITGDPPKLGDYPDASGVFDLDAIGLARLARNLNSGFDAGGFSIDPPTGMVIGV
GANPLAVEPEREISRYREKVDAGAEYAITQPVFDADALLRFLDRVEAAGCRIPVLAGLYP
LLSFKNAEFMSQHVPGVVVPEDVLRRMATCTTKEEGMRMGARIAAEIRDRVAGRVAGFQV
SAPLGNVTLALEVLDL
>A0A3D2G6W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MNIQEYIRTHKLITDGAFGTYYADRFQTQDMPELANISFPQRVTAIHQEYIEAGARLLRT
NTFASNTILLHADMNEVRANITAAVNLAKEAVKGREDVFIAGDIGPIPSDEVISREELEE
QYYQIARVMLDQGLKILTFETFHELQYILPAIGRIKEEAPDTFIMVEFTVNQFGYSSAGL
SVKSLLKDASACKDIDAVGMNCGIGPAHMEKLLDQAGVGISGTKYRIALPNAGYPRRTSS
RIRYSNSSAYFAAKVEEMAAQCELDIVGGCCGTTPEFIRQLSQGLDTTPCPPRTAAETSK
TEQVVPQRKGFLYDEQGNLKKKKLIAVELAPPMGADDEKVLEAARLLQKSDVDVLTFPDS
PSGRTRIDSVLMAEKVRRETGMEVMPHICCRDKNAIAMRSLFLGAYINDITNMLIITGDP
VPSLVRQTIKAVFNFDSVGLMKIAQEMNTENFPARPLSYGGAISQGRKNLDVEIMRVKKK
MEAGAEFFLTQPVFSKEDAERVRRIKQETGTRILCGIMPFVNKRNALFMKNEIAGIIVPD
EVIARYPENGTKQEGEAVGVEIAREIMEFTADFADGYYFSFPFNRVYLLEQILR
>A0A6H3IRT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Hz7|TrEMBL
MPHTSDPACRKIPFSFELYPPTSDAATSVLHATIERLAAAGPEFISVTYGANGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSNAESSQLIREFLDAGVRSFLALRGDPPEGIREGEAF
LGDLGSAAELVQLIHRVQAERVPYREAVIPGLPAARTIKREREKVRIAVAAFPNGHPRSR
SATQDIDALLAKQAAGANLAITQLFFHADHYLSFILRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRQATELARQLIAGGAPGLHLYAFNQHE
TVLAVLDGCGLLTPTLPASALPAPHPVKENS
>W2XTW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora parasitica CJ01A1|TrEMBL
MGKIIESIRSAYAARADDASARPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGAERWSPVEGGLSNAVDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIQWISDCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPEKVLTALDAIKNDDAAVRRYGTQLAVETCRRLLAAGVNSLHFYTMNLATT
VTQVLEGLQLLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRTELWGTPQTEEDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAAIRENLQWLNSNGFLTINSQPRVNGAPSSDPSVGWGGDDGVVFQKAYVEFFVA
PEKIAHLVKVMRRDYPQLSFHALNRRGDEHRNTPLHSVTAVTWGVFPGIEIVQPTVVDSD
SFAAWKDEAFELWQTQWASAYPEGSCSREVIQHIYDSYFLVNIVDNDYANDDSDIFSIFT
RIITEAMDKEELRTRVLELEARREKMFDTLASFQSLQKDLNGELRAAHSELAGVRGENLQ
LKEKVRQLEAQLALASL
>A0A3Q3ALK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kryptolebias marmoratus|TrEMBL
MVNQVQRVDGGWQSGKSDSSGASNSGGESSKESSRCSTPVLDADRSDRLRDKMRRRTESR
DHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGSDWEEEEEGFNYAV
DLVKHVRSEFDEYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLVVPEEITEVIEPIKDNDAAIRN
YGIHQAVEMCQVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWVEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLRMWGEELKNEESVFDVFTSYITAQPNGNGHQVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHVTGHSGPRMVSVR
>A0A162K2S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tistrella mobilis|TrEMBL
MTVTTDGRVLTPRALWDAPAPVPGLKISLEFFPPRGAQAEARLWENVARLAAYAPDFVSV
TYGAGGSTRDKTRDTVLRMRRDYGLAAAAHLTCVDASRADVMAVAEGYLADGIDHIVALR
GDPPQGAGPYVPHPDGFPFAVDLVRALADLGRFEISVAAYPEVHPQAQSAGADLDNLKAK
LDAGATRAITQYFFDPAVFLRFRDRAAAAGITRPILPGLMPVLGFQQIKRFSAACGAGIP
DWMERLYDGADADETTHQAVSAMLLAEQARVLAAEGCADLHFYTLNKAELTISACHLLGI
RPRAEVAAARAAG
>A0A349BY39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKVIDILKQKEVTVSFEVFPPKTDAGFASVSGATRKIAALRPDFMSVTYGAGGGTSKNTA
RIAADLQNTYGTTVLAHLTCVSSTRETVSSMIEKYKELGIENIMALRGDIPAQGRTVFDY
DHAAELIYDIKSRAEDICIGGAC
>A0A0S9QGC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Leaf288|TrEMBL
MSIDLSTPPVPISFEVYPPRSDAGVAALHETIRHLASVDPRFISVTYGAGGSTGGRSLEL
LTHILRETHVEPLAHLTCVGNSYAAANALIREFLDAGITSFLALRGDPPAGVSEDDVFLG
DLDSAAQLVQLIDCVQAEREPYSEAPIPGVPGAVRVAERPRVDIAVAAFPNGHPRSRHPF
EDIDALLAKQAAGATLAITQLFFHADDYLAFVQRSREAGVTIPILPGIMPITSPTRLRRV
LELTGEQLPVDLAVALDVEPTVEGQREVGVAHAARLAREVVDGGAPGVHLYAFNNHETVL
DVLSEAGVLAPSMRMPDAVR
>A0A3D4RAH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKLSEKMKEKQLLSFELFPPKTEKGMANLPGTIEHLMEFKPEYISCTYGAGGGNVGANRE
VCQMIKKAGSIPVTHFTVIKNTKEGIREQLDQYLEEGVDHMLALRGDFPMGETSTMGDFD
YATDLVKFVRDQYGDKFEIAVAGSPEGHISCRSLEADIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGVTMPVDVGVMPILDQAATINMALSRNGCVMDRELSRLISRHWLFPN
PFAAKDAEGKPFDLFYDKKIAEFKEEGIEYTIRQIDTYRALGVEGIHLYALNKWKDVSEI
INRSGLRTLV
>A0A512UN48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metschnikowia sp. JCM 33374|TrEMBL
MKISEKLKQAHAGPNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSSLTNEMVYTAQSTLGLETCMHLTCTNMPVSYLEEALDKAYKAGCQNILALRGDPPLD
GSESTGDFRYAKDLIAYIRKNYGDHFNIGIAAYPEGHPEEEDDEKLLQYLKEKTDAGADF
IITQMFYDVDNFIAWCRRIRDYGINIPIIPGIMPISTYSAFIRRAKWSEVAVPQHFLDAL
DPIKEDDYAVREIGSQLVAELCQKLIDSGFVNHLHFYTMNLERSTIMLLERLNLIECVKD
NEAVGEDLPWRKSLHPNRSKEQIRPIFWQNRKYSYISRTSGWDEFPNGRWGDSRSPAFGD
IDLSASQLLRQSPKRALELWGCPQELKDLANIVISYLKNEVKALPWSDGPIGTDTDVLKD
SLIKLNENGFITLNSQPALSAVRSNDQVYGWGPKNGFVYQKQYLEFLVHKNVAPQLLKAV
ESHNNADPTGLITFYLVDKEGNLTTNSKDDDINAVTWGVFPGEEILQPTIVEKVSFLAWK
DEVFSLIDEWVTIFHSKAISELVEQSKIETLSRFLTDFGNDYVLCNLVNNDFTSDNNVMF
QLLNSLSGPSN
>A0A182ISG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles atroparvus|TrEMBL
MASHTINSITDENSKDLHTKLRAISSHPPGAVSHLCYSVEVSAKDDFNPELLGDLSPQPI
FCSLPWISDENLRYEENFLQAPPLRMSTKLQKAGYTVVNHLSCYNLTEQQVGKFLATGVR
NLFIIRGDTVTPGQRFPKAADLVQYLRDRQQEDGVKLTIGVGGYPYGHSQSKSDTDELRY
LKEKVAIGVDFLLTQTLYDAESFFGYRERCKQVGINIPVIPGIYLPHSYSHLQTMLKITN
ITLPPTLHASFETHAEDPPEQFEAFVVEHFVGVLRELLAPNDVSRDPVRCSLFLPISGLE
GGALGEDTVVGVAALGGAADEALDTPELFVIMLSFDAGTRVSVPFDVFETVSTPSLSFRE
PPPFAEGASFAAPDWFSLFAVPFGTIVPTVFIVVVVVVVVVVVIGAVAYPISTSKASAAF
HLAAFFVMPTPVALLPAALTSIVNWRRRPTVGRSFSTSVYTGCFSLRACWICMSREMGFS
FSVNTSPATDFSLIRLRGFFFTVVPTSRGDASAVDAVAAVF
>A0A412UNZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus bromii|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGIESVAHLTCINSTKADIDRNLALFKENGIENILALRGDRVEGVEPQKD
FAYASDLCRYIASQGDFDIAGACYPEVHSEAADEVEDIHNLRKKVESGASHLISQLFFDN
SVYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A3D5WH42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKITQLLQEDKVTLSLEVFPPKKDTAVEQVSRSVREIAALQPDFMSVTYGAGGGTSAYTV
QIAKDIKAEYNVPSMAHLTCVSSTKENVKKQLECMQEAGIENVLALRGDIPADAEFPLPD
QFHYAVELVRYIKQIAPEMCIGGACYPEGHPEAVSKAQDIQHIKEKVDAGCEFLTTQMFF
DNSIFYNYMYRLREAGVLVPVIAGIMPITRKNQVGRSIQLSGSCVPARFKSIVDWFGDDP
AKMKQAGIAYATDQIIDLIANGISHIHVYTMNDPEVAAGIMNNLSAILH
>A0A351UUJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIIDKLQDGKVHVSIEVFPPKTDAKYQEVIEAVDQIAAMRPFYISVTYGAGGGTSRNTV
KIASHIKKDLGVESLAHLSCVSSTRETVRQVISELQQEGIENILALRGDIPTDPEIPVAK
DYQYASQLIEEIRKQGDFCIGAACYPEGHVDSRDRKEDICYLKEKVDRGVDFLTTQMFFD
NMVHYSFLYRIREKGITVPVIPGIMPVTNAKQMRRILSMSGTALPARFQAVLDRFGTNPQ
AMKQAGIAYATEQIIDLIANGINHIHIYSMNKPEVAGAILHQLSEIIEND
>A0A163AS49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus sp. MIT 1306|TrEMBL
MSEGHSDLSSALQRSIEAGAVTITAEVMPPRGADPVHSLTMAQGLKGFVHAINVTDGSRA
VMRMSSLALCRLLLDEGLEPILQLACRDRNRIALQSDLLGAHALGIRNLLCLTGDPVRVG
DQPEARPVHDYESVKLLHQVAAFNRAEDPVSGLLPDGATALFAGAAADPNCKSLSGLRRR
LERKKEAGARFLQTQMVMKPAVLEHFCNEVANPLGLPVLAGVFLLKSARNASFINRVVPG
ACIPESLVVRLEQASDPMAEGIAIAAEQVRSYLSLTQGVHLMAVKAEERIPEILDQAGIS
LVPM
>A0A3C1XKW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MNIQRLFESKKVVYSLEVFPPKKTTSIDTIYNTLYGLRGLRPDFISVTYGAGGSEAQKNK
TCEIASLIRSEYQIEPVSHLTCVGSTKQDIMEFLDRLKAEGVQNILALRGDITPGNDIID
FEHASDLAAFIKNYDDSFNISGACYPEGHCDSANLDQDIENLKKKVDAGVTHLVSQLFFD
NNHFYEFMDKVEKVGIHVPIEAGIMPVINKAQIERTVSMCGASFPVKFSKLLNKYAQDPI
ALKDAGIAFATEQIIDLINNDVRGIHLYTMNNVETATRITNSISNILASCNRQV
>A0A2M9B4Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter chitinivorans DSM 11115|TrEMBL
MKVTEHLSRADGKTLFSFEVLPPRKGENIQTLFSNIEPLLEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFKAEPDGHAYACDLIGQVSNLNKGEYLDEEQDDTWATDFCIGTAGY
PEKHFESPNYGADLRYLKHKVDRGADYIVTQMFFDNEQYFNFEKRCRDAGITVPIIPGLK
PLTTKGQLTMLPRSFYLNIPEELAEAVHHAPDNEAARQIGIEWCINQSKELMAHGVPCLH
YYSMGKSESIRRVASQLF
>A0A2G2E3Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fluviicola sp|TrEMBL
MKVTDHIKASKETLFSFEILPPLKGKSIQSIYDGIDPLMEFNPKFVNVTYHREEYVYKER
ENGLLEKISIRKRPGTVGICAAIMNKYDVDAVPHLICGGFSREETENALIDLQFLGIDNV
LALRGDSIKTESNFRPHKDGHQFAEDLIKQIGEMNGGSYLMDDITLEPTNFCIGTAGYPE
KHFEAMNLHTDLHYLKAKVDAGAEYVVTQMFFDNEKYFAFVKACRKIGITVPIIPGLKPI
KSMNHISFLPKFFHIDYPEALSKELLKCKNNKEVEIVGREWGIHQSKELKAAGVPCIHYY
TMSNSSSVKAIAKEIF
>A0A3F3H150|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructobacillus tropaeoli|TrEMBL
MQSVTDFYQDHRGPVISQELTIKNGLKSACARDQAQYFSLANQGQTDHDWQTLLKTATKV
QLTTKKPVMVHVRAKDVQPDQVESTFHHLQDLGLNNFLLVTGDKRADSNGFSSAQDLLVA
TGQTGLAELCLATTLDVNQVANHGVAWVVNQALAKERAGAKVLISQIFFDVDNFLAVQEG
LKMAGSDLILVAGVLHYPSQNQLDWVQRVLRLTVPDDWRKNPDLASARLVADLTDGQAAG
IHYFANF
>A0A257TS07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium 37-53-5|TrEMBL
MKKPFRERLKDGVIVCDGAMGTLLELYEYGEKPPEIHNLKNPDIVERAHREYIQSGAEII
ETNTFSANRLRLEGYRLDDKTKEINEAAVRIARAAAEDNIYVAGAVGPSGRLLQPLGKTK
LSDVKKAFKEQIGYLVSGGVDLLILETFLDLNELDAAIDAAKEISKDIPIIAQKTFSEDG
AILASDFPLEVVKHIKSKGVDVVGSNCTVGPQRMYGIIKSVYSEDVILSAQPAAGIPTLV
DGRSIYHATPEYLATYAKQLVEAGVTVVGACCGSTPSHIRAIAEAVRGVKIEPKPVVVRR
KTTVEEETPGVALPSRSEFSKKLGRKFVTTVELDIPRGLDISSVLAGARSCKENGIDAVN
ITDGARARIRMSSIAISHLIQREVGIEAITHITTRDRNMIGLQAELLGAHALDLRNILVI
TGDPAKIGDLPQAQSVFDIDSVGLVRIVKSMNDGSDSMGNQIGAPTSFLIACAANPSADR
FDYEIEKLVRKVESGADVIFTQPIYEINTFSRFMKAIEPLKVPVVVGILPLRGHKHAEFL
HHEIPGIFIPDKIREKMFRAGADAAQVGISISAEFLREVKSVIAGAYLLPPFKKYEVAFK
VLEMA
>A0A8H6T1I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycena chlorophos|TrEMBL
MKVTQKINQADKENKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPASKVDVALREAKLSGCRNVLALRGDPPAGKDE
WEAVEGGYVHGIDLVKHIRREYGDYFDIAVAGFPQHQLLPPEERDQEMKWLKEKVDAGVD
FIFTQMFYDVQIFIDWVHSVRAAGITIPIVPGIAPIQTWNGFMRATSLAKTIIPQSFLDA
LEPHQNDDEKVRAIGTKLVAEMCRKILDENLGIRGLHFYTMNLEKGTKMLLEELNLVPRV
ETVKPLPWRQSLTPTRRTETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGEPKSFTDVADLFARFCGRSLKALPWSDQAPAGETSIIASQLA
RMNRYGFLTINSQPAVNGAKSEDPVVGWGPRNGYVYQKAYLEFFVQPELLSLLLTHIERD
SNITYYVINARGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGQQ
WAKIYDAGSHSRKLISELMDTCFLVNVVHNDFHDTEAIFQPFFKAGEEYLAGKPKLNGTH
>A0A833E8P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrodictium delaneyi|TrEMBL
MRILGELEPSKNGEKLAKRVEKLMPVVDAIDIPEAPMGKPIAHAAILASYIKARYGIDTV
PHIRVIDVNTVGLLSILGGLKATGIGEAVLLRGDAPIVGSEVRDLSVETAAEIAVEKLGR
NPQLGAMISLRYPLEAITDRLNAPLSFYLILRPGYSLEKLRQVSRLARSLGKQLYAYVIV
ASNKNYNKLKNMLIGQPVYSVGEATRFVEKIRDLVDGILVSSPGDVDAISEAARQIKREL
CLSLR
>K9YLY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacterium stanieri (strain ATCC 29140 / PCC 7202)|TrEMBL
MDSNLSKLRGAIALKEFLITAEVTPPKGGNPERMLGVAKLLKNRVHGVNVTDGSRAVLRM
SSVTASALLLQEGIEPICQVTGRDRNSIGLQGDLMGAYALGIRNILALTGDPIKAGDHPQ
ARAVFELESIRLLNLINKLNQGFDINNKPLSDGKLDLFVGAAVDPQSKSWSGLQRRFEKK
LEAGAQFFQSQLITDFDKLDKFMNQIAVKGDRPILAGIFLLKSAKNAHFINKYVPGVEIP
DHIIKRLEKAKKPPPRRNKNRRGTNKNGTGYMSRSSFNGSKKRRINS
>A0A8I2JNS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus alvei|TrEMBL
MKNFREALREQIIIGDGAMGTYLYQLGYPVGISYEILNVSDPDVVRNIHKQYVDAGAQLL
ETNTFTANREKLYRHGKEHLVKDINRAAVRLAREAAEDRAYVIGALGSIRAGKRENVHTN
QVIRDYHEQLSAMLEEGVDGIMFETFYDLEEMRLALQIVRELDHDVPVICQFAVEESRRT
KDGKSLLEAFRVLRDDGADVVGLNCHMGPTGVLRALEGVQGHIDLPLSAFPNAGLPDYVD
GRYNFVATAEYMAQSAVQFVQMGARIIGGCCGTTPEHVAAIVGALQDVEVPELPVQPVES
ISIEEEAESLHWHDGATCYDGCGHGHHAEESIVDMVRSRHTVIVELDPPRDLDISKFMKG
AKVLKEAGIDALTLADNSLAVTRMSNMALGYMALDQIGIRPLIHIACRDRNLIGTQSHMM
GLHALGIDHVLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNSGLAFSGKPLKQKAN
FVVGGAFNPNVKHLDKAIARLERKIEAGADYIMTQPVYDVDLIERIAEGTKHLNVPVFIG
IMPLASGRNAEYLHNEVPGIQLSDDVRRRMSGLEGEAGRKEGVAIAKELLDVALTHFKGI
YFMTPFMFYEMTAELTRYVWEKAERQADPLYRLT
>A0A8H3WQX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum asianum|TrEMBL
MDKITDKIAALPADANYFSLEFFPPKTVMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
SQKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKSE
YRTAEDSDVEDMDDFVWAIDLVKYIRKKYGDYFCIGVAAYPEGHADESHPLGQSFEHDLP
YLVDKVQAGADFIMTQLFFDIKAYDNFEKVLREHPSGAFKTIPLLPGLMPIQSYQMIKRT
TKLSHAKVPDALMARLDAAKGDDEKVKRVGVDILSELVEQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPEHADDDNESAIIDDAVGGAAVVPTVQLNGLNPMSAVPRALSNSN
RRASSIGSDPHNRVIVSSASNPAYETTAASLSAEPVNTRANTLAISEGEGVLGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHMSVTQAVGLWGTPKTVQDINNLFIRHIKGQLSAIP
WSEEELLPESNIIQQELLELNSRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKSFVE
FFLPSADWAGLVARLNEVKDKSICFYAANAAGDFVSSDSSGGLVLEGTETSTNAVTWGVF
PGKEIITPTIIEEVSFRAWAEEAFKIWGEWAKVYGKGSESEALLERIRSEYWLVNIIHHD
FVERDALWKLLSGEKEI
>A0A829M7B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus MAB_091912_2446|TrEMBL
MTTNPLDRDGPVAELQDPGRSPIGSPRSSPARSRSRSSSCRPDEAAEARLWRAARVFERY
RPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRGI
TNILALRGDPAGDVNAEWIPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLES
DTANLVNKLRAAPSTPSRRCFSTSTTISGCATGW
>A9B657|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)|TrEMBL
MANPFLEQLGQRALLCDGAMGTQLYGRGIDFDECFDALNLTQPDVVREIHQSYIEAGADI
IETNTYGANRFKLEPFGLADKVRQINHRGMKLAREAREIAGTNTLIAGAVGPLGVLLQPY
GPLTEQAAHEAFAEQIGTLLEQGADLLMFETFSDLREMLIAVKAAKQVGDLPIVAQMTFA
EDGRTVLGNTPEEVVRKLVELGVAVVGVNCSVGSQRVFRVVQSMRAVNPTIPISAQPNAG
WPTERHNRVFYPSSPEYMADYARRMVEELNVQIVGGCCGTTPQHISNMHSALQDLNPAST
LNITIVDDEVPSVQLPSKSAETTQLGRMLADGAFVTSVEIDPPKGHNPRRCLEGARQMQA
AGVNFINVADSPMARVRMSALPMCNLIQQQVGMETILHFTTRDRSLMGLQSDLLGAHALG
VRNILALKGDPPSFGAYPGTSGVFDVDTIGLVKVIAGMNSGVDTAGNDIGTPTNFLIGVA
LNINAEDPDWEIDRLHQKVAAGAHYAMTQISYDATELDRFLDKLGPLPIPIILGLMPVQS
YRHASFLHNEVPGITLPKDVLERMKEAGANGRAVGVQVSQEILAAAYDRIQGVYIMPSFG
RYEMAAEVLEVLKAANA
>A0A1F3CXC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium RBG_16_67_12|TrEMBL
MGTMLYARGVPFDHSFEAANLHRPDLVRGTHLAYLEAGAELLETNTFGANRLKLAAHGLD
DEVESVNAAGVRLAREAIALAGRPAWIAGSIGPLGRRMAPLGATPESEAGEVFAEQARAL
AGAGVHLIMLETFFDLNEIVAAVRAVQRVTDLPIIAQMTFAQDGRTLLGYTPEEIVARLE
PLGVAMIGANCSVGPHGMVDVLDRMAAASRTPLSAMPNAGLPAYIGGRFAYMASPGYVAE
HAVSLVQMGVSVVGGCCGTTPEHIAAMSAAVAGHRTGAPRRRAPATVAPPPPPAPAMEPP
GTFAQKLGRRFVITAEVSPPHGADDAEELETCRRFRAAGVDAIDVPDNPMARLRMSPWAT
AARVQREVGVETILHFTTRDRNLIRLQSDLLAVHALGIRNVLVLRGDHPQTGDYPQATEV
SDIHPSGLVRMIKEFNQGRDVAGNAIGEPTRFLVGVALNMAARDLGREIRGLERKLAAGG
DFICTMPIFEPRTFDAFLARYGRLPVPVLVGILPLYGAKHAEFLHNELPGMAVPEAIRAQ
LRDAGDGREMGMTLARDLLAAIRDRIDGIYLIPSFGRYERILHLAREMRAALPAR
>A0A7W4GFB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. SG41-4|TrEMBL
MAFHHAQHAQSLNQSLSELNDINVSFEFFPPSTPAMEEILWNSIRRLEPLNPKFVSVTYG
ANSGVRDRTHSVIERIQKETNLLAAPHLTLVDASDEELVELAKHYWNSGIRDIVALRGDL
PDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDARNAQADLINLKKKIDAGANRAI
TQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVTNFKQTKRFADMTNVAIPHWLHRQFEG
LDDDPATRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A0J8J8N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria fleischmannii 1991|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRAFEELSLTHPEDVLNIHKAYIEAGADIIQTN
TYGANYIKLKRYGLEDEIKRINQAAIRLAKRATSGTGTYIFGTMGGINGASDSKVEQAPL
DEIKRSFREQLYCFLLEGVDAILLETFYDPNELKTVLQIVRENTDLPVIANVSMHEPGLL
QNGEKLPDVLQEIANLGADVVGVNCRLGPYHMARALETVPLLDNAYLAAYPNASLPEMQE
GKIIYQAETDYFQEYGEIFRKQGARIIGGCCGTTPEHIRAFRAGLTSTKPIKTKEVRPII
ELVPEEPSPLEGVRLLDKVREGCTVLVELDPPRTFDTEQFFEGAKALHEAGADAITISDN
SLATPRISNMAIASILKHEYDIKPLIHLTTRDHNLVGMHSHIMGFHKLGLHDVLAVTGDP
TKVGDFPGASSVFDLRSVELIQLIKKFNDGISYTGKSLKEKARFHVAAAFNPNVLNVEKA
VRLIERKVEYGADYIITQPIYDTQKARVLNEALEEAQISVPVFVGVMPLLSSRNAEFLHN
EVPGIRLTNEVRERMREAEKAGRGNEEGMLISKEIIDSISEHFNGVYIITPFLRYDLSLE
LLQYAKSKEQVHVI
>A0A834CM38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzias melastigma|TrEMBL
MVNQRLEGGWQTCRSDSSGGSNSSGESSKDSSRCSTPLPDGDRTDRLRDKMRRRTESGDR
WFSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVN
YCGLESVLHLTCCNQTREKITGYLAKAKHLGLKNIMALRGDPIGTDWEEEEEGFNFAVDL
VKHIRSEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTFLK
FLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEDITKVIEPIKDNDAAIRNYG
IHLAVEMCSVLLESGNVPGLHFYTLNREVATMEVLRQLGLWLEDPRRPLPWAVSANPKRK
VEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALL
QMWGEELKNEQSVFEVFTSYITAQPNQSGHKVMCLPWNDDPLAPETNLLKDQLEKVNRRG
VLTINSQPNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSSENVAALLKVLKKYEPRVNY
HIVNVHDQNLNNAADMRPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKL
YEDESPSRMIIQYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPEPLHSETV
>A0A7Y7AFR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTDHIKASKETLFSFEILPPLKGKSIQSIYDGIDPLMEFKPKFVNVTYHREEYIYKER
ENGLLEKIAIRKRPGTVGICAAIMNKYQVDAVPHLICGGFSKEETENALIDLQFLGIDNV
LALRGDSIKTESNFRPHKDGHQYAEELIKQITEMNNGTYLMDDVTLEPTDFCIGAAGYPE
KHFEAMNLQTDLHYLKAKVEAGAEYIVTQMFFDNEKYFAFVKACRDIGITVPIIPGLKPI
KTMNHISFLPKFFHIDYPEELSKELLKCKTNSEVEKVGLEWGIHQSKQLKEAGVPCIHYY
TMSNSSMVKAIAREIF
>S3A9I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. oral taxon 186 str. F0373|TrEMBL
MTAPLRLREATRRCPKRMVHGPCGGVAIDGGCEVPGIRCSFVDDPAVLHDLEFSAAEVDA
PNAARASGDALPVSPRGEASTAFAALVDADAVITADLPVRSTDPAVITEAGVRLRELTAV
IAGEPPGLRDALSLTHKALLLAAAGSRVVAGLTCRDRNRVALEGELAALADLGVSGVLAV
TGDHPASTALPQAQPVFDLDATRLTALARRAGLFVAVAEQPSAPPVDHRPVRLARKAQAG
AELGILNLCGDLAEIRRFTAALATTAAPVPVLVSVPVLTSVATARRLAALPGVGLPDELV
TAVAGADDPVDAGIAAAVAWARRALAIPGVVGIHLSAIAAAASAPTAGAADAAELTAVDA
LASAAARLRTAIATDAIAAETAGTA
>A0A2G9XE44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium CG23_combo_of_CG06-09_8_20_14_all_48_27|TrEMBL
MTLPENLKSKKFVVTSEVQPPIGIDVQELARSVERIRGKVDALTVPELKIEGLVTDMMGT
CRVLKEQKFEAILQTTCREKNRLDLQDHLLHASEAGIENILTFTEDYRLTGDSLQEIMFF
HVDSGKLFSVLDGLRDGHDISGREIPVKSRFCVGAGIDASCGKKVPDMELKEMEEMAGLG
TQYFLTTPVFDLDSFKQFMKQVEPMRIPVIAEVILVRSAEMCLFLNKHVKMGLVPNFVIE
KLARAPDKEKVSIEIVSDLVKGLRHLCQGVHFIPIGAEDRIAKYLEAAKL
>A0A127ERE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoplanes sp. Z2-YC6860|TrEMBL
MAAPIRVSFEFFPPKSEEMEKSLWEAIGRLAPLSPNFVSVTYGAGGSTRERTHSTVKRIV
NETALTPAAHLTCVAATKDEIDNVIQAYRDAGVRHIVALRGDPTSGIGAKYAPHPGGYQH
AADLVSGIKRIADLEVSVSAYPEKHPDSPSVQADIDMLQAKVDAGATRAMTQFFFENDRY
FDYLDKVRARGIDIPIVPGILPVQNFKQMKSFAERCGTSVPRWLAERFDGLDDDVATRKL
IAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRPARAEVPLSSLSQGARVP
ARSAGG
>A0A3N1SMG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 840.1|TrEMBL
MDSLSTAAAPALAALLDDFSLEMTGKDVPALEEARDRIPAGTRINITFLGSEDPDTRLAA
ARTVRRLGCTPVPHISARRLRSRPELEEFLAALRSDGTAGDVLVVGGDPATPHGPYDDSL
AVIGSGLLQSYGVRHVGISGYPEGHPAIAAPALWSAIEDKTTALARHGLSGDIITQFGFD
AGPVLAWVEAVRRRGIDAPVRVGVPGPAGIKRLMTYATRFGVGTSTSVAKKYGFSLTNLM
GTAGPDRFIHALAEGYDPHRHGVLKLHFYTFGGIGATSRWITEFRAGAGG
>A0A5S5CZM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus xanthinilyticus|TrEMBL
MKRALTVRDTATRASLRRTFEDLGYEVIPFKKTQEQVLAHVPKDVRLTVTASPAKGQDAT
IDLTVALAGHGYAVAPHLSAQQVRDRGHLADIVARCREAGISDVFVVGGDPAETPTEFQD
AHALLVALHELDHGFTEIGIGGHPEGHPAVSEDVLFQALKDKAALATHIKTQIVFDPAVI
LRWARELARRGIELPVHVGVPGAVHRQKLLRVSGGLGIGESAKFLKKQQTLLWRFFVPGG
YSPDKIIKGLAPHIGKPDNHLEGFHVFTFNDLAPTEAWRQKMLTDLA
>A0A2D8JLH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVIEHIKKAKSTLFSFEILPPLKGKSINSIYESLDPLMDFKPPFIDVTYHREEYVYKKR
GDGLLERRSVRKRPGTVGICAAIMNKYQVDTVPHIICGGFNKEETENALIDLDFLGVENV
LVLRGDPIKSETYFTAEKGGHRYASDLLTQVKGMNQGVYLDEDLRNSSPTSFCIGVAGYP
EKHFESANMKSDIHFLKKKVDAGADYIVTQMFFDNQKYFDFVDLCRENNINIPIIPGLKP
ISTKKQLTLLPQRFHLNLPNLLVDEVLKCKDDDQVRQVGVDWSKQQVKELIKFGAPCIHF
YTMGRSDNVQKIVSNFA
>A0A1H4ZI40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 3213.3|TrEMBL
MAFGIASTRTDRARTVRDMLATGKNTYSFEFSAPKTPKGERSLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPMADWVAHPRGLTYAAELVRLIKESGDFCVGVAAFPELHPRSPDWDTDVRHFVD
KCRAGADYAITQMFFRPESYLRLRDRVEAAGCATPVIPEVMPVTSVRMLERLPQLSNAVI
PDALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPKA
>A0A4Q3KZZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKITQHIAEAKKTLFSFELLPPIKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKEQ
ENGLLEKVSYRKRPGTIAICAAIIHK
>A0A128FE35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grimontia celer|TrEMBL
MGYSHASHLDALNQNLSDLNGDINVSFEFFPPSSEAMEQTLWASVQRLKTLKPKFVSVTY
GANSGERDRTHGIVKSIKQETGIEAAPHLTCIDASRDELREIARDYWNSGIRHIVALRGD
LPEKSQKPDMYAADLVELLKGEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIIPGILPVSNFKQASKFANMTNVRIPAWMYKQYE
GLEDDAVTRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPTA
>A0A543FYU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia cypriaca|TrEMBL
MADLASALRRVTYEVLPLGRTEEAVVAHVPHDVPLTISTSHAKGPEPTVDLAVRLAGHGY
SVTPHLAARQIRDGTHLSDLVARLHDAGVDKAFVIGGDSPEPAGSFGDALSLLEALDGVG
NPFQSIGIAGYPEGHARIPGALLETALERKAPYATHAITQICFDADATIGWARHVKQHGI
RLPIRVGLPGVVSRQKLVRISAGLGLGQSARFLLKQQSLFWRFFLPGGYHPGRLAGRLAP
HLEQPDAHLEGFHFFTFNEVASTEAWRRSLLARIS
>A0A2E6SXZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MLRDKIQNREAGIVLYGMTPPKENTQIERVREIASKHVSRIQSLDIDGVVLYDIQDESAR
NGDTRPFPFLPTFEPQKYSGDFLSELNLPKVFFQVVGKHSEASLANWMQNNLNNGDLGVF
VGNSSSNQETQITMDQAYEIRKQYAAEMPVGGVAIPERHYAKKDEHLRIASKINKGVSYF
TTQAVYNVEASKNMLSEYYYHAQSNNLPLVPIMMTFSPCGSKKTMEFMQWLGIHFPKWLK
NDLTHSKDILGSSIDTCLRTFRELVDFSLKKGIPIGANIESVSIRKDEIDASVELLENVK
DILNKKL
>A0A6G1JYC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pleomassaria siparia CBS 279.74|TrEMBL
MHISQKLAQARAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHSFGPQFVDLTWGAGGRLA
QLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDNALRDAHQSGCTNILALRGDPPREKEK
WEATAGGFRYAKDLVKYIRDRYGNHFDIGIAGYPEGCEDNDDVDLLLDHLKEKVDAGATF
IVTQMFYDADLFIDWVKRVRAKGIDIPIIPGIMPIHTHAAFIRRATWTKCNIPPHWTAAL
EPIKNDDVEVREVGKVLVAELCRKLIDAGILHLHFYTMNLAQATRMVLEELDLLPDMNSP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDARSPAFGELDS
YGVGLKGTNEQNIKLWGAPTSIKDISELFVRYMGGKLDSLPWSEAPISKEADSLQNDLLD
LNKRGFLTINSQPAVNGAKSTDPVFGWGPRNGYVYQKAYLEILVSPEFIAEVITRIDRDP
NLTYYAVNKDGDLKTNAPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQDW
ANCHASISPARYVIEDLMDTWYLINIVHNDFHVTHGIFPLFDGLKVQDMEKPLHSTGITN
GTPNGVSDHTSNDTTTNDEKSVLTTAVDAAKSATQAVTNGINGLTVSN
>A0A2N2FRA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-7|TrEMBL
MQSNRFKEALLNPSEFPVTWELVPGRGAKEAAQEKALALAGQAATGGKIHALTLTDNPGG
TPAMSADFMGCEILKLGIEPLVHFTCKDKNRNQMESQLYALDRAGIRNLLVMSGDYPASG
FQGRPAPVFDLDPIHTLQLISDMNRGLTYPGIKGNIIHQTSDFFPGAVVSPFKATEAEQM
VQYYKLKKKIAAGAQFIVTQLGYDARKFHEVLLFMKQNGFNIPLVGNIYILPFGAAKMMN
RNDLPGSVVTDKLLADIDRERNDPDKGEGARILRAARMYAIMKGMGFSGVHIGGHNIKYE
QVEAIIRQGEELAPRWTELIRYFDYPIPDGFYYFERDPDTGLNRETATTRQNRPLDARIE
FPYGFSRFFHQVMYEPGKKLYGVMKSLCTKVEGTKMEGFFHKLEHLTKVALFDCKDCGDC
ALIDAAYLCPMSQCPKNQRNGACGGSFRG
>A0A507ALH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thyridium curvatum|TrEMBL
MHIQEMLAEAERTSQPSFSFEYFPPKTAQGVQNLYDRMERMYHMGPKFIDITWGAGGRHA
ELTCEMVAQAQTYFGLETCMHLTCTDMGEEKVNNALKKAYQAGCTNILALRGDPPRDQEK
WEATDGQFQYARDLVAYIRKTFGNHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGATF
IVTQMFYDVDNFIRWVGRVRERGITIPIVPGIMPIATYASFIRRANHMNCNVPPEFMAAL
EPVKNDDVAVREIGKTLVADMCRKILAAGIRHLHFYTMNLAQATRMVLEELDWMPSAAKP
LKQALPWKQSLSLGRREEDVRPIFWRNRNKSYVSRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLPGTNEQNRKKWGEPKSVQDIASLFLRYLDNDIESLPWSEAPLTNEADSIKDDLVD
LNKRGLITINSQPAVNGLKSSHPVHGWGPPNGYVYQKAYLELLVAPEVYPQLIARIRANP
DLTYYAVTKTGDLDTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGADW
ARCYDVDSPSRALITDIVENWHLINIVNNDFHQPKTIFEVLAGLRVNNLVTPVEPKSATN
GVGAAHN
>U5MQ98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium saccharobutylicum DSM 13864|TrEMBL
MIREYLKNNVLICDGAMGTYYSELTGNDITYCEFGNINNKDIIKRIHEEYINAGAKLIRT
NTFSANRYDLGISFDKLKDIITLGINIAKEVTENTAVFIGASIGPIREESIDECDNDILD
EYKFIVDCFIENNIDIFIFETLSNYNYLEEICGYIKLKNPNSFILTQFAVKPDGFTRDGL
SVTKIINNVKGINQIDAYGFNCGSGPTHIYDIIKKINIDGDIVSALPNAGYPEIIHERTV
YPNNPVYFAQKVNKIKSLGTSIIGGCCGTNPVYIKELANLVNKNVNVVNTLTKNEEETNK
FENKQENSFKNKLDNNEFVIAIELSSPTNTDISKLMQGAKLCKENNIDLVTIPDSPMSRV
KAESTIISAKIKREIGIEAMPHICCRDKNINAIRSGLIGAHIENIRNVLAITGDPISDAS
KVETKSVFNLNSFKLIELIDDMNSEVFNNDNILIGGALNLNVLNKEVEFNRMMKKIEKGA
NFFLTQPIYDDDAIEFLKKIKERTNVKILAGLLPIVSYRNAMFLNNELPGVTIPEKYINM
FSEDMTKEEGQQVGIDISVEIGRKLKGLCDGLYFVTPFNRVNMLIEIINKIKG
>A0A3C0PC52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacteres bacterium|TrEMBL
MHIRDILNTHSTSFSFEFFPPKDEKASDRLFKTINDLIQLKPLYVSVTYGAGGSTRELTQ
NLVMRLTRETRLTVAAHLTCVCSTRLEIKGILENYVKNGIENIMALGGDMPKNGICPVIP
ASEGFERAPDLVAFIKKNFPSLGIGVAGFPEGHPRIPNRLKEIDYLKSKVDAGADYICTQ
LFFDNHLFFDFCERCVLAGINVPVIAGIMPVTSLKGMQRMAELSACTHFPARLLKAMARA
EDESHVEKVGIHWAAEQVSDLVDKGVKGIHFYTLNQSDATLRIYDSLGLTNSDRLSI
>A0A1T4MSP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enhydrobacter aerosaccus|TrEMBL
MSPDTGPLSSSPLAGGTAEFPARAPQRLKVSFEFFPPKTEAMEHSLWEAVKRLAPLHPTF
FSVTYGAGGSTRQRTHDTVVRLKTETGIEPAAHLTCVGATCGEIDEVARAYWDAGIRHIV
ALRGDPPSGMGGKYTPHPGGYANAAALVAGLKKIAPFQISVAAYPEKHPDSPDADADLEN
LKRKVDAGADRCITQFFFEADDFLRFRDRAAAIGIEAPIVPGIMPVSNYQSVARIAGLCG
SKVPSWMAQLFDGLDDDAETRRMIAATVAGDLCRRLRDEGADQFHFYTLNRADLTFAICH
LLGVRPARAGGVS
>A0A2V4LL86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mosselii|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALLAEYQAAGIRRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFETDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQQLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A261ERP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoscardovia suis|TrEMBL
MSEKTQQGESSQEPAAQPAEVSPAVSAAKSAAEPAKGSAAASAQRRRDHVPVFSLEVFPP
KRNASVGTIYDTLDGLQGVDPDFISVTYGTGKQADRTATARICNTIRQEYDIPVIGHLTA
QYLDEQGASEALEMFEQAKVRGVLALRGDAVPGREPAGVFDHASDLAAFIRRTHPDLTIY
GACYPEGHPQSVSLKEDVENLRKKVDAGVSHLISQLFYDNADFLNFVQMARAEGVDVPIE
AGIMPVMNVGQVRRMGKLCGARIPHALDRMLDKWQDDPRSLRAAGIVYASQQISDLVAQG
VQGVHLYTMNHPGITRRIWQNVGDLFETQA
>A0A679J291|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium bullatum|TrEMBL
MPTASHHRASRDGYRPIQVSIEFFPPKTDEMEKVLWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMIKETSLKPAAHLTCVDATREEIDEVVQSYWDAGVRHIVALRGDPQDGVG
TAYRPHPGGYARTSDLVAGIKRIGDFKVSVSAYPEKHPEAATLDADIDALKAKVDAGADQ
AITQFFFENEVYLRYVDKVRAAGIDIPIIPGILPVQNFKQSANFARRTGASVPYWLAARF
EGLDNDVDTRRLIAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKV
AAAKAA
>Q1K0Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas acetoxidans (strain DSM 684 / 11070)|TrEMBL
MLMKEILDQGRISLSFEFFPPKTVVGGERLFDNIAELAPLAPSSVSVTYGAGGSTRSQTH
DLVLRIHNETGVTVVPHQTCVAATRDDVAMILAEYEQNGIENVLALRGDPPLDDPDWTPP
VNGFAHAIDLVKFIRERFPGFSIGVAGFPEGHPEMPNRLLEIDYLKQKVDAGADYIVTQL
FFDNRDFYDFCDRCCLAGIEVPIIAGIMPLRTRKGMMRMAELAAGARFPAPLLRRVTEAD
SEEDVEQIGIDWAIEQVKDLVAHQVSGIHFYTLNSATATCEIFSRLGLR
>K9FMU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium digitatum (strain PHI26 / CECT 20796)|TrEMBL
MEKKITEKIAALPQDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKALGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRQTHGDYFCVGIAAYPEGHPADTFQDLQDPVRDIPY
LVEKTLAGADFIMTQLTYDIEAYQKFENTLRNHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIARRMEELKHDDEAVKRAGVDIVSEIVGGIRDIPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPSYSDAGDLAIEDDPASIPLDFPGRALRRRRASSINSQPHNRVVVDKL
SVHGSSQDSVHEARADSAGVPAPPPSRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTANSARRLWGHPVDSKDMSTIFRRHVSGELHMVPWSEGGAEEDGEG
LNAETELIRPELLKLIDGRGWWTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFC
SSNDYTNILKPMFAKHGHDKLTWFATNIKGDFESSLPIQPADVELDDLGSNPESVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTEAYLDTTKNDSWLVCVV
GQQFGAGTKQGSKEEEDEVKWMWRVLAGEEV
>A0A7Y9NH30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. JAI102|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKVFAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFDAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASELISFI
RAEHGDAFRIEVGAYPETHPQANDALLDLKHFKTKIDAGADAAITQYFFNADAYFHFVDA
VRKLGVTVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAESVRAFGAEVV
ASLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLRS
>A0A1S3HII0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lingula unguis|TrEMBL
MKDLQHSPDRSPQNGTPATPSPNSSRPESPGLLPYKYISLMDRIKAKIADDEPFFSLEFF
PPKTEEGAVNLVARLERMLLGGPLFCDITWHSAGDPTSDKHTSSTAIAGTMLNYVGMETM
LHLTCIGASKATMINQLERAKELGIRNILALRGDAKFGEEWKPEPDGFNYATDLVRFIRL
HYGDYFVICVAGYPSGHPDCESYEADLQNLKTKVDAGADFIITQLIFQSKTFLKYVQDCR
NIGITVPILPGIMPFQSYQSLRHITRLSKMEIPQEILDEVIPIKDNDEAIRNWGIDIAYR
MCSEILAAKGAPGLHFYTLNREVATVSVLKRLGMWCEEPKRMLPWKPTANHIRCMEDVRP
IFWRARQKSYVQRTSDWEDFPNGRWGDSSSAAFGALKDHYPFYLTSKSSHEELLSMWKKE
LNSEEDVWDVFYHYITGEAYDDGVKVTRLPWEDDEVTLETSLISSELASINRKGVLTINS
QPRINCVPSTDPAVGWGSHDGYIFQKAYLEFFVSKEKVDCLKEILPEYPLVNYHIVNCTG
EADYTNCDEHKPIAVTWGVFPGREIIQPTVVDPVAFKAWKDEAFMLWLNPWADLYPEGSR
SQELIRYFHDNYYLVNLVDNEFPKETVLWEIVDRMCSMAESRSDGAVQQEEACQPKFQKL
AASQ
>A0A3D2PVI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp|TrEMBL
MNIKEYIKEQRLITDGAMGTYYEEKYSEDTVIAEKENLKNPEQIKEIHLEYLRAGARLIR
TNTFAANTMFLADMQEVKETVRAGYEIAKEAVTAFQAENGKEIPVFIGADLGPIYDLDHQ
DYDNVLQEYKEICDTFLSCGADCFVFETQSDFTYIEPVTAYIKEKSDAFILVQFAFDKSG
YTRSGLSMQRVAVEASEMENVDAYGFNCELDSTHMYQFMKNLKFSSDKFVSALPNAGYPY
TLRGKTIYSNNASYYAEKMKDIAALGTDILGGCCGTTPEYIALLSGELQDVPKAVKKIEN
VVTQEVTRTPSIFEEKLSRGEKAYIVELDPPFSEDASKVMKGAEDLRKCNVDLITLSDSP
MARARMDAGQLAVKIQQKTGVAVMPHISCRDRNVIALRAGLLGMHMNDIRHFLIVTGDPV
SRADRERVTSVFDFNSIKLMQYVKEMNLEVFAQEPVYYGGALNYHGTNPDAIIERMKRKA
EAGCGYFLTQPVYTEEDVERLTYIKEHIDTKIMCGIMPLVSYKNAMFVKNEMPGIHVSDE
IVNRYREDMTREEAEEVAIELSVEIAAKLYDIADGFYFMTPFNRTGLIARIIEAIRQEEE
RR
>A0A7T1DY23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diaphorobacter sp. JS3051|TrEMBL
MSLSTAFPVSFEFFPPKTPEGADKLRAVRQQLYARRPEFCSVTYGAGGSTQAGTFGTVRE
ILAEGVSAASHFSCIGATKDSVRAQLAELKAMGVKRLVALRGDLPSGYGIGGEFHYASDL
VAFIRAETGRDFHIEVAAYPEVHPQARSSDADLQAFATKVRAGADSAITQYFFNADAYLR
FVQDVRRLGLDVPVVPGIMPIMGASQLLRFSDACGAEIPRWIRLRLQGYGDDVASIRAFG
LDVVTHLCEQLRREGVPGLHFYTMNQSAATLEICDRLGL
>A0A6P5WBJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila obscura|TrEMBL
MEQRLWHCIRRLAPLAPRFVSVTYGAGGTTQAGTLSTVLRLKRETDLIPAAHLTCVGANR
EDVLLTIYSPRPGGYAYASDLVAGLRRIADFDISVAAYPETHPTASSPDADLDNLKRKLD
AGVTRAITQYFFDNEIYLRFLDRCLAAGITAPIIPGIMPVSNYEQIVRFSAVCGVTVPAW
LRHLFDGTTKNPELRRIIASMVAVEQIRTLQTYGLNEFHVSTLNRSDLTYAIAHILGVRP
PQTNASRNVTGLLETMEIPDERETAANFDPIEGTQEGAPPFMLRTLFG
>D4JC63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus catus GD/7|TrEMBL
MDIREYLANNRLITDGAMGTWYDRLTGYKGKLAERANLDDLQQIRDIHRAYIEAGARLIR
TNTFAVNSMFFSADEIEAVLKAAWENACQAVSDSGRDVWIAADMGPIDENETKSAADVEN
EYIHLADCFLGLGAKIFVFETLSEFRSVKKAIAYIKAECPDAFIVTQFSFNRNGYTRSGL
SVRALLLEAAAMKELDAVGFNCGVGPLHLYELLKNQSFPEGKYMTVLPNAGYPTELRGRT
FYSENVPYYVDMMGRIAALGFDIIGGCCGTTPEHIRGLHDLLVNDVRPPKKLMPAVYSAD
GKENCAEEAVEEKTDFIQKLERGEKVFVVELDPPFDVNDTKLMEGAALLRDINVDMITLA
DSPLARPRADSIASAIKMRYTRQMEAMPHICCRDKNMIAHRSQLLGMQMNGLRHALIVTG
DPIARGDRESIKSVFNFNSIKLMKYIQTMNQEVFGSRPIYYGGALNHNNGSIDNIAARMC
QKMEAGAQWFLTQPVYGQEDIDRLKELKEKSGGRIIAGIMPLVSRKNALFIKNEMPGIHV
PDQVLERYEAGMSREAYEDVAEAISVDLMKRLEDVCDGYYMMTPFNRAALIKRIILQAKK
ELR
>A0A5B1QK35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dentipellis sp. KUC8613|TrEMBL
MKLAEKFASSERPFYTLEFFPPRTDQGFGNLISRISRLAELKPIGVSITWGAGGSTRARS
LELAAVTQKDLGLDTIVHVTCTNMEMGVVDETLRAVKDSGVQTILALRGDPPRGKESWIP
TDPRFDHAIDLVKYIRAHPEFSDWFSIGVAAYPDGHSDHVLTEDEELGYLKDKVDAGADF
IITQLFYDVDNFLRWEGKVRERGIKVPIIPGIMPIQTYASFLRLTKLCGTSIPPFLEKDL
DAIKHDDAKVKDYGVSLAISMVKRLVNEGGIRGFHFCTLNLEKSVQRIIESLDWAQAPSI
NQTPNRLIADTPGVVESASNDPAHTVTPATATTSATSGLAMHAAREGEIGKGEANSAATW
DEFPNGRFGDVNSPAFGSQDLWGGFSSLHSSTLSQWPRPKSVADITDICMRFLTSETTSY
PFSPSPLSTESQRILPQLKRLARLGWWSVGSQPAVDGEPSEDPVIGWGPTGGYVFQKPFI
EFFADEDVVKRLEKKVKEKGKGWVDYLAANFEGGFKSNVQEGQRNAVTWGVFPGQEIIQS
TIIEQESFLTWKEEAFSIWTEWASLYPPKSQERELLEGIRNSRWLINVTHHDYKDPEGLW
NFLFEDTPEAPGSGEQ
>A0A1G4J2N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea meyersii CBS 8951|TrEMBL
MKVSEKLQKNLESNEKSKATFSFEFFVPKTSQGVQNLYDRMDRMYQTRPQFIDITWNAGG
KLSQLSTDLVSTAQSVLGLETCMHLTCTNMPVQLIDDALEKAYASGCQNILALRGDPPVT
TGEWKQCEGGFAYAKDLVSYIRQKYGDHFDIGVAGYPEGHPEEEATPQLIEFLKEKVDAG
ANFIITQMFYDADIFIDWCRQVREAGIDVPIIPGIMPITTYAAFMRRANWCQIHIPDDFM
SKLDAIKEDDQAVREMGTQLLTEMCQKLLDSGYVTHLHMYTMNLEKASLMILDKLGLLTE
EEDIFRDEVSPMPWRRSLHPQRRNESVRPIFWQRRPYSYVARTSEWSADEFPNGRFGDSS
SPAFGDLDLLGSSLIRQSPQRALELWATPTSITDISNLVIGYLQGKIKCLPWCDVALNHE
VDTIMPQLLDLNKNHIVTLNSQPRVSGISSSDSVLGWGPNNGYVFQKEYLEFLLPKSKLP
QFTEIIGDNTSLTYFAVDASDKLYSNHPDDTAANAVTWGIFPGREVLQPTIVEKVSFLAW
KEEFFHILDEWQLILAQDGHTDSAALLDTIIRDYALVNIVDNDFVTVGDRIHDRLKLLY
>A0A4Q9GR18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciihabitans arcticus|TrEMBL
MTDATFSFELYPPRSARAEELLLDSLEHLVAAGPEFISVTYGAAGTTRGASLAVLLRLLG
DTDVKPMAHLTCVGSSYAEATRLIREFLDAGVTSFLALRGDPPTGAVEGDSFLGDLGSAG
ELVQLIHRVQAERVPFRQLDVPGFPGAKRLGSGEKVTIAVAAFPNGHPRSRSVEQDLDTL
LAKEAAGANLALTQLFFHAEDYLRFVDQARAAGVTMRILPGIMPVLSPQRLHRIVELTDE
RLPTDLLRNLEAQSTPEGQAEVGIQHAIDLSRQVIGTDRPGLHLYTFNQHEAVLAVLRGV
GLLPSQSAPEKESV
>A0A0K6FSD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKVTEKIRQAEKDGRVWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSELVKTCQGAIGIETCMHLTCTNMPQEKVDVALKEARANGCRNILALRGDPPSGQEE
WTSVEGGFQHGIDLVRHIRREHGDYFDVAVAGFPQTIQLPEAEAKQEMQWLKEKCDAGAN
FIFTQMFYDADVFIRWVKAAREAGITIPIVPGINPIQTWNGFIRATSLSGTEIPQDLMDI
LEPHKNNDEKVRELGIKIVADLCRKILNADIGIKGLHFYTMNLEKGTKMLLEELNFVPRV
ETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQTPEEGRKIWGTPTTLDDIKSLFAKFCSQQIKALPWSDQPPSTEMLVIGQQLA
RMNELGYLTINSQPAVNGARSDDKAFGWGPKNGYVYQKAYLEFFVHPDQLQALIKRIERD
TNVTYYAINKQGDLKTNSTSEGPTAVTWGVFPGKEVVQPTIVEAVSFMAWKDEAFELGCQ
WAKIYEPGSPSRKLIEGIMNEYFLVNFVHNDFHDREAIFRPFFVDSGLKANGDTETPAVN
GIKVNGFVNGHATAVRA
>C4KD22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera sp. (strain MZ1T)|TrEMBL
MKPEISIEFFPPTTAEGAEKLHATREKLAALEPAFFSVTYGAGGSTRERTFATVKEIAAA
GHEAAPHLSCVGSSRDSIREILQEYAAAGIRRIVALRGDLPSGAGAAGEFRYASELVEFI
RSETGDRFRIEVAAYPEWHPQAKSPKDDLAAFKRKVEAGADSAITQYFYNLDAYLNFVDA
VRRMGVDVPIVPGIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDSDAIRAFGLDVV
TRLCEKLLAAGAPGLHFYSMNMAGPTTEICRRLGLTA
>A0A4Y4KGB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 6-11-2|TrEMBL
MTPARTAQDPASRTAGGFFARPAKAALADALRNASYEILPFKSAEVKVLAHVPKDVALTV
TTTEAKGLGPTIGLAARLSGHGYSVAPHIAARLVRDEAHLTDIVSRLRDSGVDRLFVIAG
DAPEPAGAFPDALSLLEGLQSVGRTFASIGIGGYPEGHGRISDELIEKALQAKAPYASHV
ITQLCFDADTTIRWARTAQASGVDLPVRVGIPGAISRQKLIRVSAGLGLGQSARFLKKQQ
NMLWRFFLPGGYSPNKLIERLTPAFGMSGNRLQGFHVFTFNDLDSTEAWRQAWLARLS
>A0A376DY81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter universalis NCTC 9529|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPAGSGKPEMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVELKT
A
>A0A1E3G278|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium thailandense|TrEMBL
MILGCELLEKRFILETLPPRGTNWEKYVEFCTGAVKSGAQVIAVTDLPMGSSRVSPIAPA
HILVEKGFEVLMHFSRTTRNAIRIEGDLIAAHMLGVKNLLILSGDDPRVGTYPFASYIED
FSIYDVFKLVELMNKKSENLAGVKLYGKFDFCTGGVFSPYEKDVVGTVNRMRGKFDNGCA
FFISQPVFLPEAMETFLSKALEMDDEMFSKVKIYVALMVFETVSQMEYFSKVPGVYVPKE
YFNHRTDEDLKAYSLKRVLDVVEALRPYVHGFYLTATVRDFELIQQVAEAVL
>A0A0K6FXB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKLTEKLANYASDVPYFTFEFFPPRTDQGYSNLLTRISGLASLKPIATSVTWGAGGSTRD
RSLDLAGFCQADNGLDTILHLTCTNMEKGTIDEALTTAMERGVSTVLALRGDPPRGEEYW
IPADPRFRHAEDLVTYIRQHPKFGGHFCIGIAGYPDGHSEGGTEQEQLTYLKRKVDAGAE
FIITQLFYDVDKFKSWLRKVRNAGITVPVIPGVMPLQTYATFTRMTDLCKATVPQHIQAN
LDAIKHDDQLVKEYGVSLAVSMIRSILVDGDIKGVHFCTLNLEKSVRKILDELGWTHESL
HHNQIIIDASQSPHILPAPADAPHPVAFTISPSEATQYATTSLAEHTRTGTVRTAAEAID
SGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPPHVAITQWGRPTTEQELSDLFLAYLNG
KTSTTPFSPEPLSDESTTILPHLVSFTKRGLWTVASQPAVDGALSSDPVIGWGPRDGRVF
QKSFVEFFATEADLEKVAKAIEDSGDGWVTFFAGNNEDGFLTNIPDSGSNAVTWGVFPGK
EIAQPTIIDRDSFLAWKDDAFMIWHDFGQCYPPDSPTRTLLEDVIKTRWLVSLVHHDYKN
PNALWDFLAKHLD
>A0A6P0GH28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus normandii|TrEMBL
MTRSVRELLASSRPTWSFEFFPAKTPEGEAQLWTALRQLERLQPSFVSVTYGAGGSTREG
TVAVTERIAAETTMTPLAHLTAVDHSVAELRHVVSRMAAAGVRNLLALRGDPPGADPQAE
WVRHPEGLEYASELVELIRSMGDFSVGVAAFPERHPRSPDFETDVAMFVRKCRAGADFAV
TQMFFRVEDYLRLRDRVAARGCDVPLIAGVMPVTNARQITRIVQLSGQAFPEELAARFAE
LDGDRPEDKAAVRAYGVEVATEMCRRLLDEGVPGIHFITMNRSTATREVFLNLTDADTGT
SVPSTLAATP
>A0A1U8N204|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium hirsutum|TrEMBL
MKVIDKIQSLSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
NIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DVLVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A7C0YI47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MTLEKKLEEKAFAVLAEFEPPKGADFSEMLNNAVNVKGRIDAFVVPEMASAVMKASSLGG
SLFLQINGLEAVVQVCCRDRNRLALQADILSAAALGIRNLMVVKGDDIAVGDHPQARAVN
DLDLFELLDVIKQLQAGKDMAGIELKGSPR
>A0A7U9BKD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli H299|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7Z7J7D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus taiwanensis|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
DGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVKAGADSAITQYFYNADAYFRFVD
DVRALGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A7X9XF27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. SM-530-WT-3G|TrEMBL
MITEYLKNNILICDGAMGTYYSELSGNDISYCEFANLNNRDIIKKIHCEYIEAGAKLIRT
NTFSANTYDLGITRKELKDIISEGINIAEEAVGNRNVYIGASIGPIRNEYMEENDDEILE
EYKFIVDCFIEKGIDIFIFETFSSYHHLDKISEYIKKKNKNNFILTQFAFKPDGYTRDGV
GVDNIFENVKNNKYIDAYGMNCGSGSAHLLELVRKIKISKGDIVSILPNAGFPEIIHERT
VYPNNPIYFARRINDIRMQGAVILGGCCGTNPLYIKEIKKILEKKDFKEVKKNEEISKKI
DSSDNVSNTFKNKLKNNEFVIAVELTAPVDTDVTKLINSADICKKNKIDLVTVPDSPMSR
VRADSVLISAKIKREIGIEAMPHVCCRDKNTNAIRSSLIGAHIENIRNVLAITGDPVSDI
SKVKTKSVFNLNSFKLINLINTMNTDVFFNNGMLIGGALNPNVRNKHVEYERMKKKIECG
ASFFLTQPIYDEEAMQFIKEIKEKTNTKILGGILPIVSYRNAVFLNNELPGVNVPECIVN
KFKEGMPKEEAQKVGMEIAVDIGRKLKDICDGLYFIVPFNRVDMIMEIVKNIR
>C6CG35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya chrysanthemi (strain Ech1591)|TrEMBL
MSFFHANHQEALNQNLAELQGRINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPPGAGKPEMYASDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRSELSYAICHTLGVRPATLA
>D5SY14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctopirus limnophila (strain ATCC 43296 / DSM 3776 / IFAM 1008 / Mu 290)|TrEMBL
MTVLTTPNALPSTNLRSLYASGQFALSIEIFPPKTAEGDAALRQALQEFSTYNPAFVSCT
YGAGGSTRSRTLDWCREIIDRVGVAPTAHFTCVGSNSDELIDWLGQAWQLGVRNIMALRG
DVPQGETEFKAVEGGFSHARQLVELIRKEFPEMGIGVAGYPEKHPEAVSLETDIAFLKEK
ITVGGHAVFTQLFYDNETFYRYWEMCLKQGIDAPIIPGVMPITEYSRVKRIVEISGTKVP
AELLEQLEAAHLRDDKAAQLEIGIEYSVQQCQDLIDHGVPGLHFYVLNKAHATSQILQSL
GLKNSEITTG
>A0A559REM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olleya sp. Hel_I_94|TrEMBL
MKVTEHITRGKGKTQFSFEILPPLKGQHIQSIFDNIDPLMAFNPPFIDVTYHREEYHYKD
LGDGLLKKQVVKKRPGTVGICAAIQNKYNVDAIPHILCGGFTKEDTENFLIDLDFLNIDN
VMALRGDAVKTETYFTPEKEGHAYASDLVKQITALNKANYLDDQLLNCSATDFCVGVGAY
PEKHMEAPSLESDIHFLKKKIKNGAEYVVTQMFFDNQKYFQFVDKCRNEGITVPIIPGLK
PISTLKQLNVIPHRFHVDLPEALIKSIIKCKTNVEVRQVGIEWCIQQSLELKKAGIPMLH
YYSMGKSDNIKAIAEAVF
>A0A416YBA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF14-5|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEQAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A0C1H366|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leisingera sp. ANG-M1|TrEMBL
MTTPKISFEFFPPQNLEASFRLWDTVQVLAPMDPRFVSVTYGAGGTTRTLTRDAVATLHK
SSGLNVAAHLTCVNASKAETLEIADQFAEAGVTEIVALRGDPPKGEGKFTPHPDGFSNSV
ELIKGLKARGNFNIKVGAYPDRHPEAADQSADVEWLKRKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDGSKLTPGILPIENWKGARNFAKRCGTIIPDWVENAFDKALRDDREELLA
TALCTELCSDLMEGGVDKLHFYTLNRPELTRDVCFALGITPKVALSNVA
>A0A2D7FJK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Filomicrobium sp|TrEMBL
MPEHDQMRTSRLLGAEEIAVSFEFFPPKTDKMEATLWSAVDRLAPLMPEFVSVTYGAGGS
TRERTHATVTKLVKDTQLVPAGHLTCVGASKEEVDDVVRNYWEAGVRHIVALRGDPPEGV
GQRFEPHPGGYQNTAELVEGIRSIGEFDIAVSGYPEMHPESVSLKVEMDHLKAKVDAGAS
RIITQFFFNNSHYLRFVERVRAHGIWCPIMPGIVPIHNFRQVSGFAQRCGASCPPWLVHR
FDGLDGDPGTSHLVAAAVAAEQVMDLVDHGVRTFHFYTLNRADLVYAICHLLGVRPRQAR
ALAS
>A0A1G9DKX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbulbifer yueqingensis|TrEMBL
MPVLAGTRSLGGQEKDRTMTDTPRISFEFFPPKTPAGREKLYKTRETLQEFQPAFFSVTY
GAGGTTRETTSNIVTGLRRDGISIAPHLSFGGDDEETVLGLLNSYREAGVDRIVALRGDM
PSGMGTVAQLVYANELVAFIRRHTGEHFHLEVAAYPEIHPEAESYDDDIRYLKGKFEAGA
NSALTQYFYNPDAYFYFLDQCEKAGIDAPIYPGIMPITNFANLARFSRNCGAEIPRWLKK
RMESFSNPDDIRKLGLEVVTDLCETLLAGGAPGLHFYTMNQVEPTAEILRALEIETGA
>A0A424MXV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED134|TrEMBL
MFESQNFLFTAETTPDVSTDLAASAGRVDDLVGVADAINVTDSPNSKTRLSSLLVAAEIR
RKGLDVILQLTGRDRNAIALESELLGALSAGVNKVLCLTGDQPPEGGPKAVNEFNGAGLI
QLCNTLSQGTLSDGTPIKAAKTVYPGAADDIYQHLDNENAAAGLLRKIEDGAGFVQTQYC
FDLDVIKAYAKKLSETPAFKDRKVLVGLGPLASAKQADWMRKNLWGVNISDDIVQRLEQS
HEPLREGEAICEELIGELMQLPEIGGVHLMGPNCEKRSARIIARFRS
>N9MZJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 51.11|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAADLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A7C3TLS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MRIDELLGRGLPTVSFEFFPPKSEDGWAQLYRAVGELYELRPSYVSVTYGAGGSTRRRTV
DLAIRIQTDLNIRSMAHLTCAGHTADELDGILRQLRDAGIRNVLALRGDVPAGAMRFEPT
PGGFAYANELVEFIRRSYDFCIGVAGYPEGHPQCLNRIRDLENLKKKVDAGANFIITQLF
FDNADFYRFRDEARRMGIAVPIIAGLMPIISVSQIKRFITMCGAKIPHPLLLRIEAVEHS
PDAVYAIGIEHALAQCRDLLANGVDGLHFYTLNRSKATIEIVRTLNIPHAGT
>A0A5T0MPJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A7G7KNM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. LTW-R|TrEMBL
MRLQQALEAGDFALTAEVMPPRGGEIKRTLEHAALLKDWVHAVNVTDGSRAVMRMSSLAV
CRLLLDAGVEPVWQQACRDRNRIGLQADLLGAHALGIRNILCLTGDPVRAGDQPQARPVN
ELESVRLLQQVAAFNRGEDPVDGLLPDGPTDLFAGAAADPQSPSWSGLSSRISRKQKAGA
RFVQTQMVMDEDCLKRFVDEITAPLGLPVLAGVFLLKSAKNAAFINRVVPGACIPQSIID
RLAAASNPADEGITIAAEQVSRYARTCQGVHLMAVKAEERIPLILERAGFSPRC
>A0A5R8YFU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohaesibacter sp. CAU 1516|TrEMBL
MNHNAERSGRRSQSADKLNISFEFFPPKTPKMEEKLWECVERLAPLAPDFVSVTYGAGGS
TRERTHATVERIIRETSVPAAAHLTCVGATKEEVNDVVRSYIEAGVKHIVALRGDPADGV
GTKYQPHQGGYINAADLVGGIKQLGDIEVSVSAYPEKHPESPDFATDVEMLRQKVDAGAT
RAITQFFFDNDLYEAYVERVRRAGIFIPIVPGILPIHNFVQMANFASRTGASVPQWLANR
FEGLENDEETHRLVAAAIAAEQVNDLHERGVDDFHFYTMNRANLSYAICHLLGLRPIKGA
AEQD
>A0A2E7A2G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHFEDIRQRDARTISFEFFPPASEKALERLRSKLDDFISLAPSFVSITYGAGGSTRERTH
DLVIELGQTGQVDPIPHLTCVRQTRSEVQTILERYASAGISNLLALRGDRPVDDPGEPGE
EEYAYAIDLVRHIRSFNESGIHPDPRGFGIGVAGFPEGHPETPNRLKQLAFLKEKVDAGA
HWVTTQLFFDNASFYDWRERCDLVGIHVPLVAGIMPITSMKSLHRMADLAAGTNFPARLQ
REIYRHQDDPGAVQKVGVEWAVEQCRDLLEHETDGIHFYTLNNSDVTMEIFRSLGIEDAN
ALR
>A0A4R4SLC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces hainanensis|TrEMBL
MALGIPSTMTDRAETVRDLLSAGERSFSFEFTPPRTEVGERTLWNAIRRVEAVGPTFVSV
TYGAGGSSRERTVLATERIATETTLTPVAHLTAVNHSVAELRNIVGQYAGAGIRNMLALR
GDPPGDPMAEWQRHPEGVAYAAELVSLIKESGDFCVGVAAFPEMHPRSTDWESDIRHFVN
KCRAGADFAITQMFFHPEDYLRLRDRVAAAGCDVPIIPEIMPIANVRQIERFKQLSNSSF
PPELESAILAVKDDPMAVRSVGIDFATELCARLMDEDIPGLHFVTLNTTLHSTATLDVYK
NLGLHQRT
>A0A5N0E400|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia colli|TrEMBL
MPFSVEFNPPRDAANEARLWRAVRQFERMHPAFVSMTYGAGGSTRDRTVRVTGELAQQTT
LLPVAHLTAVEHSLSELRSLVGSYADSGIRNILVLRGDPPGDPLGEWQQHPEGVAYAEEL
VRIVRDLGDFHVGVASFPQGHHRSPDLDSDTAYLAAKLRAGAEYSITQMFFDVEHYLRLR
DRIAEFDPIEGAKPIIPELMPITSLRTVARAEELCGRALPATVLERLNNAAGDDPDANHA
AVREVGIEIATEMAQRLIDEGAPCLHFITLNFAKATTEVLTNLGYGVTAAPISA
>A0A6C9ABX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYQAVKHLLKEELHA
>A0A5T2AAK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAAGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A059FVJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas johnsonii MHS-2|TrEMBL
MSTFSIADRQSDAAPSVSFEFFPPKSDAMAARLWETVQRLEPMAPDFVSVTYGAGGSTRE
RTHDTVKRIAGSTTLLPAAHLTCVSATKAEVLSVADSYAAAGVHHIVALRGDPPEGMSGT
FTPHPAGFANSVELIESLSDAGQFEISVSCYPEPHPNSRGWDEDLAFLKAKQDAGATRAI
TQFFFEPDVYLRFVERARARGITMPLVPGIMLQPNFAGLKRMAGMVQASVPAWLDRLYDG
LDDDSETRDLVTATVAAELCHKLADQGVNQFHFYTLNRAGLALSTCRLLGLKPKPAQPA
>A0A2E3KIW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHMSDVIKRDTTTFSFEFFPPSTEKSWNQLEETISQLTRLGPSFVSVTYGAGGSTRTKTX
DLVKRLXETSXLDPVPHLTCVEHDPEQIXXILXAYAETGXSNXLALRGDVPAGSVXGXHX
GHFPHAADLIXTISAFNRSGAHPDPRGFSIGAAGFPEGHPETPNRLVQMDHLKNKVDQGV
DWICSQMFFDNRTFLDWQERCRLKGIDVPIFAGIMPVTSLSGLKRMAELAAGTNFPARLL
XALEXAGPDPKNIERVGIHWATQQCLQLMDEGVQGIXFYTLNKSXATIEIYKSLGVTDSE
QLRGR
>A0A4Q8U9J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. KUL49|TrEMBL
MVSYAEGIDALNQTLSELRDIDVSFEFFPPNSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAQDYWDSGIRRIVALRGDLP
KGVDKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTSVYLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DDDDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRGN
>R6E4U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. CAG:1320|TrEMBL
MNITETLTDKTQGKRFSFEILPPLKGNGTQALFATLDELTEANPLFINITTHHSEYVYKE
MENGLLQRLRVRRRPGTIAIAATIQNRYHVPVIPHVICSGVTREDIEYELIDLQFLGINT
ILLLRGDKAKEDNHFKPTPGGHAHTTDLIRQVKRFNEGYFDDGTPISHPGEKFQYGVACY
PEKHEEAPNLEQDMLYLKEKQDLGAQYAVTQLFYDNRKYFDFVDKARAMGITIPIIPALK
PFAKLSQLSVVPKTFHCDIPQELAMEVRKCKTDDDARALGVEWATQQVRELYAAGVENIH
FYTVSAVESVKEIVKRVM
>A0A1I1VIH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora alba|TrEMBL
MTTNAQQQLQRYLRNARYEVLPLRGVVEQVRELPAGTTVTVTSSPAKGTEATLDTAARLR
DEGMHVVPHLAARLVRDSAHLSDLLARVSDLGLTEVFVIAGDAERPAGRFTDALSLLRGM
EEIGTRPHRVGITGYPEQHAFIPDRMTIQATDEKARYADYIVSQICYDPNTIASWVKSMR
ARGVELPVYIGAPGSIDPSKLLRISMKIGLGQSMRFLRKQHGVVTKLLTRYTPENVFDEL
SPCLVDPDYNIAGWHLFTFNEISKTRQWAIEMADRLQEVPA
>A0A7X8AAX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MLADKIRNRESGIVLYGIVPPKKGTEPEQLREIAQRQSQRLQSLNMDGLILYDIQDEKTR
TTEERPFPFIETLDSFSYSRDYLSSVPVPKIIYRSVGKYTRDELSEILARISEQGDLTVF
VGTASKSQQVTMSLSEAYRLKREVNPDLLVGGVTIPERHITKGDEHLRVFSKIAQGCSFF
VSQGVYDVNASKNFLSDYYYHGREQNIPLVPIIFTFTPCGSLKTLQFMKWLGISIPRWLE
NELIHAKDILQQSVEFAEQNWRELKHFAHERNIPIGCNIESVAVRKVEIEASVELLRRVS
SQ
>A0A7T7V335|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia bruuniana|TrEMBL
MKVTDHIKEAKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGEKYFEPTKGGNRYASDLVTQINDLGKGKFLHGEISGNDLNNSFCIGVAG
YPEKHLEAPSMQYDLKMLKQKVELGADYVVTQMFLDNQKYFEFVKLAREAGIDVPIIPGI
KPLAVKKHLQLLPQVFKIDLPEDLVNAVSQCKNNEAVKQVGIEWCVQQCKELLDFGVPAL
HFYTMGKSDNIQKIVSEFF
>A0A6A6F405|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cercospora zeae-maydis SCOH1-5|TrEMBL
MDKLTDKIAALPPDAIYFSLEFFPPKTQQGFSNLNARLSRMAHSLRPLFVNVTWGAGGST
SVKSLALAEVTQRELGLTTCLHLTCTNMSRKLIDEALEQAKVLGIRNILALRGDPPRSDE
YRDDSLPDAGQDDSNKDFTWAVDLVRYIRKQYGDYFCVGVAGYPEGHSDQSYPEHQSVEH
DLPYLVEKTAAGADFIMTQLFYDVDAYQKYEKRLREHESGLFKKIPIIPGLMPVQSYQIL
RRTTKLSHAALPQEILKRLEAVKGDDEAVKRVGVDVLSEIVDAMKHSEFAGPRGFHFYTL
NLEKVVTQVLERNDFIPPSTPDAELSLGMQAVAVEETDDFVVVEDAKKQQHRRRSSMANS
NPRNRVIMSRTRASSTSSNRASSAYEAFDDEAGVPREKINSRANTLAISEGEGALGREAT
WDEFPNGRWGDARSPAYGQIDGYGVSLHVSVPEARKLWGEPKSVEDISACFRRHLEGEID
SMPWSEETLQPETLTIKNELLSLINKGWWTVASQPAVNGIRSTDPVFGWGPRNGFVFQKP
FVEFFIPNDEWQKLQSRLIENPQVTYFAGNAKLDFVSNDADAVNPVTWGTFAGKEIVTPT
IIEAVSFKAWCEEAFGIWNEWQRIYKSGSESSKLLERIRKDYWLVSVIHHGFLEPGALWN
DLLDENSSGV
>A0A8C7VBS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
MIAHVNYDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRHRTESGDHWFSLEFFP
PRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLESIL
HLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYATDLVKHIRCEF
DDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVRDCRAI
GITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGIEQAVSMC
RVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHPKRKVEDVRPIF
WASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEELT
SEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVNRRGVLTINSQP
SINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGQ
NTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQWAKLYEDESPSR
MIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEQPAEQPNDEQSDK
EQPGK
>A0A847W072|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MYIKDLLSKKRPTVSLELFPPKKGDTLEKSYEVISKSVALKPDFISVTYGAGGSNNKNTL
EMADYIIKEGAVPLVHLTCVGVDEEMIISELIQQKNIGVKNILALRGDLKDGIPIPEDAK
FRFASDLVEEIMDFGGFCVGGACYAEGHVESANLDEDIENLKKKVDAGCSFLTTQMFFDN
SVLYKFLYKIREAGITIPVLAGIMPVTNGKQIRRILELSGASLPPRFKNIVDKFGHDRNA
MEQAGVAYATEQIIDLIANGVNGVHIYTMNKPDIAEGILNNISHIIEV
>A0A8C7VBP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
MHTFDKSNYAPHITHCNTALHSTCIMVNLVQRVEDTWRTCSKSDSSGASNSGCESSKESS
RSSTPVLDTDRTDRLRDKMRHRTESGDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLF
IDVTWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGL
KNIMALRGDPMGADWEEEEAGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDED
LRHLKEKVDAGADFIITQLFFRADTFLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVK
LSKLEVPEEIMQVIEPIKDNDAAIRNYGIEQAVSMCRVLLESGEVPGLHFYTLNREVATM
EVLRQLGLWIEDPRRTLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWG
NSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKV
MCLPWNDDPLAPETNLLKDELDKVNRRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQK
AYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIV
QPTVVDPVSFLYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDN
CLWQVIDDMFELLDNPPEEQPAEQPAEQPNDEQSDKEQPGK
>A0A350XYE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKITEILNNGKMSLSFEVFPPKTDTAFESVQQATHEIAKLKPAYMSITYGAGGGTSRYTL
DIAEDIMKDYGVPTLAHLTCVSSSKATVRERIAEMNRRGIKNVLALRGDIPAEMENEDRS
GWEHQYAVDLIREIKESGFDFCIGGACYPEIHPESPNQKEDIKHLREKVEAGCEFLTTQM
FFDNNLLYNFLYKIREAGITVPIVAGIMPITNAKQVDRAIKLSGSFMPQRFKIVDKFGSD
PLAMKQAGIAYATDQIIDLYANGVENVHVYSMNKPDVAQKIQSNLSDIL
>A0A2Z6ES47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycoavidus cysteinexigens|TrEMBL
MSQIELSFEFFPPRTAEGMDKLRATCTQLAVLQPHFVSVTFGAGGSTQQGTLDTVLEIAR
NGLKAAPHLSCIGAARDNVRAILARYRAHDIRHIVALRGDLPSGMGEIGAFQYASELVEF
IRTEHGDWFHIEVAAYPEYHPQAHSPNQDLESFARKIKAGANAAITQYFYNADAYFRFVD
DVRRLGIKVPITPGIMPITNFSQLMRFSSMCGAEIPRWIARRLESFGDDKASIRAFGIDV
VASLCQRLLNGGAPGLHFYTLNGAVATSAICQQITLNR
>A0A0L0ASA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella sp. RIT-PI-d|TrEMBL
MSFFHANQREALNQSLAEVQGRINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKDIKERTGLVAAPHLTCIDASRNELRAIAQDYWNNGIRQIVALRGD
LPADGGRPEMYAADLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAE
>A0A1Y2GMK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lobosporangium transversale|TrEMBL
MKITDKIAQKQAEGKPFYSFEYFPPKTAQGLSNLYDRIGRMQALSPMFVTCTWGAGGSTF
EKTTELTAVAQTVHGLDTCMHLTCTNMDRGKVDEALAEAKRNGIQNILALRGDPPRGQEY
WTQVDDTFVHAIDLVRYIRQQYGDYFCIGVAGYPEGHMDNTTFSSEEEIGFLKQKIEAGA
DFVLTQLFYDVDGFLAWEKQCRSLGITCPIIPGIMPIQSYNGFRRITSLAKVRIPTEVAQ
ALDPIKNDDQKVKDYGVELAASIIERLLNAGISGFHICTLNLEKSVRLILERIGLVPKAS
TWKQQQQHLTNEPTHVNINSQEGPIVGIDSTDANLNPMIWTPTKDLTGRSESWDDFPNGR
WGDARSPAFGDLDGYGASLKVEPRKALEMWKEPKNTEDISQLFVQFIQGKIPLLPWSEGS
PLPETEAIQSRLVACNERGLWTVGSQPAVNGKPSTDPLFGWGPKGGYVYQKAFLELFVGP
NEVEGIVQRLRTVSPWITFFAASRDGEVLTNTTGDDSNAVTWGVFPGKEIIQPTVIEKVS
FLAWRDEAFEIWREWEQLYPKGSESRKLLHQIGHDYWLLNVVHNDFRDENGIWDIILS
>A0A2E8G8T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MMNNVPRLREALATRPFVTTIEFNPPKGTDVSKVMTLAGKMVGMVDGVNVTDNTAAVLRA
GSISLCRLLYEIGHDPVMQITCRDRNRLAIQSDLLSAHLLGIRNLLCLTGDYPTVGDHKD
AKPVYDIDSIQMMQIIDGMNQGHDMNGKTLNGMTDLHVGAAMTPDMLPRGLAQTKFETKV
NAGAHFFQTQAIFDAVRFKEFMAFARQFQVKVIAGIILLRSAKMARFLNDNIPGLSVPQD
MVDELDGVPEDKACDVGIDLAVRTINAIRDSCDGVHLMTITAIDRLPELIKRAELR
>A0A3D5P8R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MLTSQLFRKKKVFSFEVFPPKKDSSVSTIYKTLEKLKALSPDYISVTYGAAGGSSRLSIK
IASDVKNIYGIESVAHIPCINMTKSEVLAELHELKKNGIENILALRGDIDPSVPPKHDFK
HASDLIAFIHKHGNFNIIGACYPEVHPEAKSAEDDLQNLKMKVEAGVSQLITQLFFDNSS
FYRFRERARAVGINVPIQAGIMPVTNKKQIARIVSLCGVAIPEKLSEIIEKYGDDPASLR
EAGIAYAIGQISNLAANGIDGIHLYTMNNADVAKKISEATVPLICHK
>A0A354F4P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
RIKNELDIEAMAHLTCTGTSCENLKRILDKLQENGIENILALRGDKPQDTNSIAQMPQCY
NHTNELIQYIHDNYDFCIGAAAFPEGHTESPSLEKDTYYLNMKSMAGAEFFITQLFFDNR
LYFDLLDRASKIGINKPIIPGIMPITSADQVERFTSLCGATIPSDLRERLHEIRNDRRAV
MELGIGYATKQCQDLLSKGAPGIHFYTLNRSSATRTILKNLL
>A0A679K894|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp. ghe19|TrEMBL
MAQTNERKSKLLGSGDILVSFEFFPPKTEKMEETLWSSITRLAPLGPEFVSVTYGAGGST
RERTHATVTRLIKETPLKPAAHLTCVDATKEEVNAVAKTYWDEGVRHIVALRGDPAQGTG
TKYEPYPGGYKNAADLVAGLKAIADFEISVAGYPEKHPESPSIEADIENLKAKVDAGADR
IITQFGFDNAHFLRFIERARAAGIWVPISPGIVPIHNFKQVAGFAKRAGATVPSWLARRF
EGLEDDSATSHLVGAAVATEQVMDLVDEGIKKFHFYTLNRADLVYAICHLLGLRSVRAAN
ADAA
>A0A0F3GXH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Magnetobacterium bavaricum|TrEMBL
MSFKETLQSGKFVVTAEVGPPKGTDIATMLHDMHLLKGKLDAVNVTDNQSAVMRINSMAV
CKLAIENGLEPILQMTCRDRNRIALQSDLLGASVLGIHNVLIMTGDHVSAGDHKGAKPVY
DIESVQLLQVVDGLNNGKDMYGNALKGATSFFQGAVVTPESNPIEPQLMKFKKKVKAGAN
FFQTQLA
>A0A354NE43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKIPELFKNGRTVFSFEVFPPKKDNDVSVIYDTLDQLGGLHPDFISVTYGAGGSAAGAST
IDLVKRIKSHCHTESIAHLTCVNSTHADIDEKIKEFEANGIENVLALRGDINPNIPPKHE
FLHASDLIEYMKPRSDLSFSGGCY
>A0A102DF41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. FSW06-99|TrEMBL
MTDCLSPIAADAPLFAGLPGDIAVSFEFFPPRTEAMDEQLWDAIGTLAPLDPAFVSVTYG
AGGSTRERTHATVARLVRETALVPAAHLTCVGASRGEIAEIADRYWEAGVRHIVALRGDP
QPGMGGQFAPHPDGYANAAALVAGLAARHPFDLSVAAYPEGHPESPSPQADLDNLKRKID
AGATRAITQFFFSAETYFRFLDRALAAGITVPILPGIMPVTNLAGIRRMGGNTAIPSWLE
AMFTGLDDRAGPRALVAAVVAADLCRRLYEGGVRDFHFYTLNRADQAFAICQLLGLRPRD
SQS
>A0A4R4PZ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella albertanoniae|TrEMBL
MANGLPSTLPGSTPTVRELLASGSRSFSFEFFPPKTPEAEEVLWRSLREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPIGHLTCVSHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWVAHPQGLNHAVELVELIRELGDFCVGVAAFPDKHPEASSLEADAQVLAA
KAQAGADYAITQMFFGADDYFRLVDRAAALGCDIPVLPGIMPVTNIKQIQRMAELTGMAL
PKPVTDRLLAVEADPAAVRQVGVEIATELCEQLLAGGAPGIHFITLNRSTATRQVFQNLG
SHVAS
>A0A3D2TRX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKISKILRDNKVTVSFEVFPPKQWDKIEHTKDIVKEMSEYAPSFMSVTYGAAGTKSGFTQ
EIATQIKNSGVTPLSHLTCITSTRDKIHTVVNDLQENGIENILALRGDIPEGFEFPDDQY
FTHAYQLVNEIKAIDPTICVGGACYPEIHPESANRVDDIEYLKQKVDCGVEFLTSQMFFD
NDKFLNFYEMCRIKGITVPIIAGIMPITNAKQIKRSIELSNSSVPKKFYKIMERFGDDER
SMKQAGIVYATEQIIDLMANGINNIHIYTMNKPEVAGAIMNGLSDIINE
>A0A5R9B299|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus xylosus|TrEMBL
MSQLLDKLKSNILVADGAIGTILYSEGLDTCPEAYNLNHPDKVERIHRTYIEAGADIIQT
NTYGANFEKLKVFGLEHRVKDIHQAAVQIAKKAANDDTFILGTVGGFRGIKQEDLELSSI
QYHTEIQVETLVNAGVDGILFETYYDLQELTNIIKATKSKYDIPIIAQLTALNTNYLRDG
TEINQALQQVTASGADVVGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSQF
KYSDNASYFGKVAEQLINEGVRLIGGCCGTTPEHIQYIKSSVAGLNPVTKKDVIPITKYI
NNTEKEPKKQNLKSKVENRPTIIVELDTPKHLDTETFFRNIKKLDDAKIDAVTLADNSLA
TVRISNVAAASIIKQRYDIEPLVHITCRDRNLIGLQSHLLGLSLLDINEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKTKTNFNIAGAFDPNVRKLDGAVRR
LEKKLESGMHYFITQPVYSKEKIKEVYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSETILEQFEAVKDDKAKTKALSLKLSKELIDTVHEYFNGLYLITPFQKVDYTLELANY
SKTITLTKQEAIL
>A0A7J5DRW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides simplex|TrEMBL
MTTGAGRSLGEIIREGGRSFSFEFFPPKDEAGEAQLWDAIRALEPYQPTFVSVTYGAGGS
TRDKTVAITGRIARETSLVPMAHLTCVGHTREELGLILDAYVAEGVSHVMALRGDPQEGP
RADWTPTEGGLNYALDLVELARSRGDFRVGVAAFPEGHPSAGSLDADADVLAAKARAGAE
FAVTQMFFRASDYFGLVERVRARGVDIPILPGIMPILNLSAIRRQGELIGTSVPDDIVAR
ISAYDGDPAAVRAEGIKVAAELCDELLAGGAPGLHFYTLNRSKATLEIFEALQITV
>A0A7K9HKS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bucco capensis|TrEMBL
MVNETQHTCSASCSSKSDGSSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKCLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7C5PZK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeodactylibacter sp|TrEMBL
MKVIEFLEQAQGKTLTSFEVLPPLKGGSMASIFKLLDPLMEFKPPFIDVTYHREDCIYKE
TASGYYEKVAIRKRPGTVGICASIMHHYGIEAVPHLLCGGFTREETENALIDLNFLNIQN
VLALRGDSRQFEKKFVPTPGGHHYAVDLVRQIHNMNQGRYLDDMIENGQKTDFCIGVAGY
PEKHFEAPNMDTDLMYLKAKIDAGAHYIVTQMFFDNKHYFNFVERCREMGINCPIIPGLK
PLTKSYQLQSIPRMFHVDIPHELVTEIQKAKNAEAVREAGIAWCIAQSQELKKAGVPCIH
YYTMGNAETIRRIVSAVF
>A0A136L334|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium OLB14|TrEMBL
MNLLETLSTKTILADGAMGTMLHARGVSFEKCFDELNLNNPAAVAEIHREYIEAGAEIII
TNTFSANKFKLGKYGLQNHVQEINKAGVELAKRVVAASFKNVLIAGDVGPLGVRIAPYGR
IKLEEAREAFAEQIKSLAEAGADLIVIETFSDVYEIQEAIKAAKEVCDLPVIASVTFTRD
DRTLLGDDPAKVATRISEAGADVIGVNCSGGPSQLLRILKQMRQAVPHGKFWIKPNAGWP
EQVSGRIMYPADAEYFGEYALLFRSAGANIVGGCCGTTPQHILMMKKALESAPQTSEVLE
TSEVSNEETAEINIQTSQLAQKLADKKFSICIEMDPPRGLSTHKLLAGASLLHDSGADVI
NVADTPMARMRMSGWAVCDLVQRQIGVETTLHFPTRGRNLLRVQGDLLAAHALGIRNLFV
VMGDPTSIGDYPEAADNYDLVPSGLIKLIKQGFNMGIDHSGTSIGQPTNFFVGAALNLCP
QDIETEVKNLNRKIKAGADFFLTQPIYHKDDGPKLIEAYEAKHGKLNKPILAGILPLVSA
KHANFLNNEVPGISIPDEMIQRIESAGEHAAKAGVDVTVELIQAIKPWASGVYIMPQFHR
YDLISEIIDQVKE
>A0A135VGM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thorarchaeota archaeon SMTZ1-83|TrEMBL
MLPKTHLRELLERGHFVVTAEVGPPQGSDAALVAERVEMIRNHCDAINVTDNPLGVPRMS
SLACARLIIDAGVEPIMHIATRSRSEMLLQSELFGASALGIRNLLFITGDEAVAKVEPRS
GIVPEMDSVGGLGLASTLMKGTNSEGEEIAGSPSFFLGSTFNPYAQSTDEEIRRIEQKRN
AGAQFFQTQAVYGVERFRDFTEKIENLDVRVLAGIVPLQGSEMAEYMNTHVPGIQISDAI
IARLRDAEEGLADEELLNAGRAEGLLIAAETVDEIRSLKGVDGIHIMGIGWYESILQTVE
RSRLHPRPTRG
>A0A2A2EZM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halovibrio salipaludis|TrEMBL
MKSQKQFKRRFSFEFFPPKSDKGAETLHQTRDKLATLKPEFFSVTFGAGGSTREGTKNTV
IELNQKGISTAPHLSCVGSDKAIISDLLDAYKEGGVERIVALRGDIPSGMGNTGYGEMRY
ANELVEYIREHSGDHFSLEVAAYPEFHPQAQSAEADLMNFKRKVEAGANSAITQYFFNVE
SYFHFIDRLEKMGVDIPVVPGIMPIVNFQKVVQFSEMCGADVPRWIRKQMEAYGDDTDSI
KQFGEEVVTRMCEQLLDAGAPGLHFYTLNQADPSMRIWKNLGLDNEVQEKIAF
>A0A2T2U9S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QS_4_64_154|TrEMBL
MKVTEHFDQASEPLISYEIIPPKRGGSADQILRVVEELMPFDPPFIDVTSHSAEVEYKQQ
DDGTWQRCVKRKRPGTIGLCAAIEARFGIDTVPHLLCKGFTREETEDALIELNYLGVENV
LAIRGDDKGYEKSISGNRSRNEQAVDLVRQIQDMNQGTYLEDMMNAEPTDFCVGVGGYPE
THFEAPNLAWDIMRLKEKVDAGADYIVT
>A0A4D6Y091|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola subsp. Melaphis rhois|TrEMBL
MNSFNSRYYEMLNEYLVNVRDKINISFELFPPKNQVLKEDLWKVISQLKLFNPIFFSVTC
GAFLGERNRTYDIANQVKNQTGIETVPHLTCIDLSKDELENIAKRYWNNGFRHIIALRGD
VKNHDNKPNMYAVDLIKLLKNVADFDISVAAYPEVHPEAHNSYYDIVNLKRKIDVGANRA
ITQFFFNVDYFLRFRDSCIRHGITIDIVPGIFPISNFQQLCKFSKMSNVTIPNWMYYMFN
GLENNSKISKIIGSSIAIDTVKVLYKEGVRNFHFYTLNKSDVVSSICHILGTRSK
>H6RCZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia cyriacigeorgica (strain GUH-2)|TrEMBL
MVQSLRLHASRAVPFSVEFNPPRDAAGEARLWRAVRTFERMHPAFVSMTYGAGGSTKDRT
VRVTGELAGETTLLPVAHLTAVGHSVAELRSLVGAYADSGIRNILVLRGDPPGDPLGEWH
KHPEGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLDHDTRFLAAKLRAGAEYSITQ
MFFDVEHYLRLRDRLIAMDPVEGAKPIIPELMPITSLRTVKRAEELCGRPLPRAVIERLE
RAAGSGPEEDAAAVRAVGIEIATEMGQRLIDEGAPCLHFITLNFAKATSEVLTNLGYGVT
AAPISA
>A0A0A0LIC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cucumis sativus|TrEMBL
MRFPIVFLLLFHLFLSLHLPFSPSLSLLLPISNSYTSQREEKMKVIDKIRAATAGDGGRV
VFSFEYFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTADLTLDIANKMQNMICV
ETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQDKFVQIEGGFACALDLVK
HIREKYGDYFGITVAGYPEAHPDVIGSNGVATTEGYQSDLAYLKKKFDAGADLIVTQLFY
DTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPDEIMAALEPIKDNE
EAVKAYGIHLGTEMCKKILTHGIKTLHIYTLNMEKSALAILMNLGLIEESKVSRSLPWRR
PTNVFRVREDVRPIFWANRPRSYISRTIGWDQYPHGRWSDSRNPSYGALTDYQFMRPRAR
DKKLLEEWALPLKSIEDVYEKFMKYCLGKLRSSPWSELEGLQAETRMISEQLGKINMKGF
LSINSQPAVNGERSDSPCVGWGGPGGYVYQKAYIEFFCSREKLDAIVDKCRALPSLTYMA
VNKEGIWVSNATQKDVNAVTWGVFPAKEIIQPTVVDPASFIVWKDEAFEIWSRGWAALYP
EGDWSRKLLDEIQSSYYLVSLVDNDYINSDLFAILEDF
>A0A286CEA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ag82_G6-1|TrEMBL
MALGTASIRSDHARTVRDMLAAGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWDADVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVSAAGCDTPIIPEIMPIASVKSLERIGSLTNAAF
PSALKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHSPQA
>A0A317KNQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. S4605|TrEMBL
MALGLPSVLPQSQPAIGELIRDRQPTFSFEFFPPKTEQGERLLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPEGVLYAEELVRLVRESGDFSVGVAAFPYKHPRSPDVASDTEHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQLSTIERSVQLSGAPF
PPALAERFERVADDPEAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLQ
VGARV
>A0A1Y2VA72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypoxylon sp. CO27-5|TrEMBL
MHINEMIAEAEKTGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDITWGAGGRIA
ELTCDMVVQAQAYFGLETCMHLTCTDMGEEKINDALRRAYKAGCTNILALRGDPPREKEK
WVASDGRFQYAKDLVAHIRKTYGNHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDMGATF
IVTQMFYDADNFIRWVGKVRERGITVPIIPGIMPIATYASFLRRANHMNCKIPEEWMIAL
EPVKNDDAAVREVGKTLVAQLCRKIMSAGIVHLHFYTMNLAQATRMVLEELDWMPTSTRP
RKQALPWKQSLALGRREEDVRPIFWRNRNKSYVSRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKRWGEPKSVQDIASLFVKYIQRELPSLPWSEAPLTSESDSIKDDLIK
LNQRGLLTINSQPAVNGVKSTHPVHGWGPSNGYVYQKAYLELLVSPDLFPEVIRRIEANP
DLSYYAVTQSGKFTTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGMDW
AHCHDADSPSRVLIEKIMNEWYLVNIVNNDFHQPRTIFELLDGLTVKDIDVPVTVSQESA
QSNGIHKEANGVSTVSGHGASATA
>A0A5R8NXH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia cyriacigeorgica|TrEMBL
MTFDNVRGRSTPGRPSSAPPIVSGTPSVVHSLRLHSSRAVPFSVEFNPPRDAAGEARLWR
AVRTFERMHPAFVSMTYGAGGSTKDRTVRVTGELAGETTLLPVAHLTAVGHSVAELRSLV
GAYADSGIRNILVLRGDPPGDPLGEWHKHPEGVEYAEELVRIVRDLGDFHVGVASFPQGH
HRSPDLDHDTRFLAAKLRAGAEYSITQMFFDVEHYLRLRDRLIAMDPVEGAKPIIPELMP
ITSLRTVKRAEELCGRPLPRAVIERLERAAGNGSEEDAAAVRAVGIEIATEMGQRLIDEG
APCLHFITLNFAKATGEVLTNLGYGVTAAPISA
>A0A1F8YKT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium GWC2_65_14|TrEMBL
MQTILDRMRETPLIFDGAMGTMLYERGVFLNACFDELCLSNPKIVRQIHQEYLEAGAEVI
ETNTFGANRIALRGYGLGDRVEAINREGVRIAREVAGDSAYVAAAVGPCIRTGQILLEGH
ADEVEASFAEQVGALAAEGVDLVVLETFTGLSELLLAARAARRFGLTVLASFMVNDRGET
ALGTLAESMAESLSANADVDAVGINCGTGPVGVFDALPSVLSATTKPVVVMPNAGFPRDV
GGRMIYLTSPEYFTEYAKKYIELGVRGVGGCCGTTPAHIRMAARAIKTLSGVKRHIEVRP
VAREEIRVEQVPTREKSRLARKLCDGEKVTSVEIVPPRSSDMSDMLAKVRRCAEAGVDAI
NMPDGPRASARVSPMISALTILREVGIEPILHYCCRDRNLIGMQSDLLGGYAVGLANFLI
ITGDPPKLGDYPEATGVFDVDAIGLTRVASNLNRGYDIGGNPISPPTGLLIGVGANPCAV
EMEREIERYYRKIDAGAEFAITQPVFDAEALFRFLDRVEGASRRIPVIAGVWPLASFKNA
EFMNNEVPGVVVPREILDRMARCRTREEGHRTGIEIARETIERILPRVSGLQVSAPFGKV
ETALAVLGKSAVEIPRDG
>A0A7Y1B4U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. WS 5027|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCETLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A7K4YLA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bucorvus abyssinicus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAIDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGISCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLRVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A4Y8I5U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium MT.SAG.2|TrEMBL
MIRSIDYLKISDLYLNSDKPVISCEFFAPKTERGFQSLNKVFEKLKQASPAFYSVTYGAG
GGTARPTLELVCKIQDEFGITSMPHLTCVNHSKEYLINYVLELKENGINNILALRGDMPD
SDGFVPHPEGLRFAADVVGLVGELNHFCIGVAAHPEGHPDSTSLEEDIQYLKIKLDAGAD
FAITQFFFDNEFYFKFLEMARNIGIDKPIIPGIIPFINSNHVMKFAKINGTYIPDLLKEQ
MFEAGDDRKRSTKLGVEQAVKQCRELLDSGVPGIHFFTLNNSKPTLSVLQRLGIN
>A0A2P2GSZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces showdoensis|TrEMBL
MNPTFSFEFFPPKTDKGEQTLWDAIRRVEALAPDFVSVTYGAGGSSRDRTIEVTKRIVTE
TTLRPVAHLTAVGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRAPWTPHPDGFTYAY
ELVELVRSLGEFRIGVAAFPEGHPRSPDPASDLAHFVAKCRAGADYAITQMFFDPEDYLR
LRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAKDDPAAAYRIG
VEHATAMGLRLLDEGAPGLHYITLNKSTAALEIHRSIHASRSLARV
>A0A1C6N8N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. AmelKG-E11A|TrEMBL
MLASGKATYSFEFWAPKTPKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRAGTVKATES
IVADSTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGAWVPHPEGL
AYAAELVRLIKESGDFCVGVAAFPEMHPRSESWDQDVRHFVDKCRAGADYAITQMFFDPE
SYLRLRERVSAAGCDTPIIPEVMPVTSVKQLERLGQLSNAAFPDELKERILAAKDDPAAV
RSLGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGLHHTRA
>A0A1J7BW61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium johnsoniae|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNKFAIDLVRQINDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFNFVAKAREMGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>W0A4L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas hydrophila 4AK4|TrEMBL
MGFHSARQVEALNQSLADLGNNISVSFEFFPPNSEGMENTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNFQTLNKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQA
>A0A2U2ACL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignatzschineria ureiclastica|TrEMBL
MSAQYVELLNQNLAELPKDVNVSFEFFPPNSEQMVKTLWNSIERLKVLKPQFVSVTYGAN
ASTRDRTHKVIQDIVTQTDLTAVPHLTCIDTSEEELNEIADNYWDLGIRQILALRGDLPK
GADNPGIYADHLVSLLKKRHDFDISVAAYPEVHPDAKNAQADLLHLKRKIDAGANLAISQ
FFFDIDAFLRFRDRCVAVGIEAEIVPGILPVSNYESLVKFAGPLNVKIPSWLHKRYEGLE
QDPETRNLVGASIAIDMVRVLRNEGIKDFHFYTLNRSELTYAICHTLGLRPQD
>A0A2E3VYG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovoraceae bacterium|TrEMBL
MTKVVDHLKNSNETMFSFEILPPIKGHGIKKLFSQVEPLMEFKPKFIDVTYHREEYVYKK
RQNGLLEKVSLRKRPGTVGICAALMNKFQVDPVPHLICGGFTKEETESALMDCHFLGIDN
VLALRGDAIKSENRFVPTEGGNAYASELVKQISDMNKGQYLYQEDAGAEATNFCTGVAGY
PEKHFEAPNFNTDLKHLKRKVELGAEYIVTQMFFDNSKFFKFVEQCRAVGIDVPIIPGLK
PLTTLRQLSILPSIFFIDMPDELVHAVESCKTNEQVRQVGIEWSINQCKELKKHKVPCLH
FYSMGKSDNIKTIASEIF
>A0A286I2E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 2323.1|TrEMBL
MRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTADLRNIIGQYAGAGIRNMLALRGDPPGDPMGEWVKHP
DGVAYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVDKCRAGADFAITQMFF
YPEDYFRLRDRVTAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQQS
>A0A4Y3WQ86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia hydrocarbonoxydans|TrEMBL
MDPAVVRQLMARFSVEITPREAPTLPPLADVLAPGTAVYLTFLPHTPWADTVAVARSVRD
AGMRPVPHLAARAVPDHATLRRMLADLAAVGVRDLLVLAGSLTTPVGEFHEAAQVLDSGL
LADAGITRVGIVGHPEGHPDVDDDELLRALLAKCRIARERGLDLHLVTQFAFAPEPIVAW
ERRIRAHGVDVPVHVGLPGLTTPARLLRFGLRCGVGASLKVLRQQAGGVLRLATSPVHHP
DATLVGVAAAAAADPACLLRGIHFFPFGALAPTAAWAGDIRDGHFVVDDRDRLRVTA
>A0A1X7CFY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Amel2xC10|TrEMBL
MSEILTTTVPTAPKLLDGFSLEMTGKDVAHLEAAREAVPPGTRVNVAFLGTETQELRLAA
VREAARLGFVPVPHLSARRLRSRAELAEFLAALREAGATERVFVVGGDPAVPRGPYPDTL
SVLRSGLLQEYGVRHVGVSGYPEGHPAIDGPVLWSAIEAKAAVLREQGLAGSVITQFGFD
VEPVLTWVEELRSRGVDLPVRVGVPGPAGVRRLLSYATRFGVGTGAGIARKYGFSLTNLM
GTAGPDRFVQDLTEGYDPVRHGDLGLHFYTFGGLAATADWVAARA
>C2P3L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus 172560W|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7X5QV44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter yeojuensis|TrEMBL
MPAISFEFFPPKTDEQREQLDAAVGRLKAHAPEYVSVTFGAGGSTLSYTDDTVKRLRANH
GLSVAPHLSCMGGTRAEIAALLDTYKTTGCRRIVALRGDLPSGMASPGDFRYASELVAFI
REHSGDHFHIEVAAYPETHPQADNALADLRHFKAKVDAGANGAITQYFFNPDAYFRFVDD
VAKLGVRVPIVPGIMPIANFSQLRRFSEQCGAEIPRWIVKRMQAHGDDAAAVRELGADVV
ADLCRRLLEGGAPGLHFYTINRARATTSVLERLATR
>A0A2E7D283|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MTPSEFTPRRIRDVYSSGQFGLSVEVFPPQTAKGDDLLYRTLDRLQSFRPAFVSCTYGAG
GSTQARTVEICSEIQSRYQLAATAHFTCVGASRDDLIQGAELMMQSGIRNIMALRGDPPA
GTETFTVAEGGLAHANELVELLREKSTDIGIGVAGYPEKHQEAADAQTDLDNLKRKVDAG
ADAVFTQLFFINDNFFEFRDRYAKAGITQPLIPGIMPITEFARIKRITSMCGAVFPEDLA
SRLEDAQDDQEQQFQIGLDHAIQQCQQLIDAGVPGIHFYVLNRSQACEQILTALGIGK
>A0A6C1DQX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces pastorianus|TrEMBL
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRD
AENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDVKLDLEYLKQKID
AGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQH
FSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANKCLELWSAPTSINDVAFLVINYLNGNLKCLPWSDIPIN
DEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL
>A0A8J3AVP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalicibacterium solurbis|TrEMBL
MTQQNFSIEFFPPKTDAGVEKLRATCARLSELKPQFFSVTFGAGGSTQQGTLDTVLEIRS
AGHDAAPHISCLGSSRDNLREILQRYKSHGIKRLVALRGDLPSGYGDFSSSEFHYANELV
EFIRAETGNWFHIEVAAYPEMHPQAKSPRDDIDSFVRKVKAGADSAITQYFYNADAYFRF
VDEVRKAGCDVPVVPGIMPITNYSQLVRFSDMCGAEIPRWIKLKLASFGDDTDAIRAFGL
DVVTDLCDRLLDGGAPGLHFYTLNQAAATHAIWSRLNLSRG
>A0A8G0JQ56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium hwasookii|TrEMBL
MKIADIYKSKNLTTSFEVFPPNDKVGLEEVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHFTCIGSKKEEIDRVLEDLERNNIENILALRGDYPVDRELEPGD
FNYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVDAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A8B4YUI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella sp. BIGb0149|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A223P0Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter xinganensis|TrEMBL
MKITEHIANAKGKTLFSFELIPPLKGHSIQGLYDAIDPLMEFKPPFIDVTSLREDFIYKQ
HESGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLEFLGIEN
VLVLRGDARMGDASFVPNPNGHSYATDLLGQVVNMNNGIYLHDNSGENLKTNFCIGVAGY
PEKHFEAPNLKSDFKYLKQKVDMGAGFIVTQMFFDNQKYFDFVNNCRANGINVPIIPGLK
PITTSKQLVNLSKTFHIDMPDDLCDLIHDCKSEKDVKDAGIEWMINQCKELMAFGVPVLH
FYTMSNAGPTRRIAEAIF
>A0A1T5DGL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter arcticus|TrEMBL
MKVTDHITNAQGKTLFSFEIVPPVKGRNIQELYNNIDPLMEFKPPFIDVTTSREETIYVQ
KEGLLDKKTTRMRPGTVGICASIQHKYNVDTVPHVICGGFTREETEYMLVDCHYLGIENV
MALRGDARSEQKYFEPTDGGHPFAIDLVKQIQDLNCGKYLHETIESEYSSEFCIGVAGYP
EKHLESPSLQSDLKRLKEKVEAGADYVVTQMFFNNQKYFEFVEAAKNIGITVPIIPGIKP
IAVKRHLQLLPQVFRIDIPQDLIEAVDGCTSNKDVRAVGIEWAIQQSKELKEAGVPVLHY
YSMGKSDNIKAIAKELF
>J3HB98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM74|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLAIYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A346SCR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria sp. AD91A|TrEMBL
MSNPEISFEFFPPKTLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRELTRDAVSTLHK
SSGLNVAAHLTCVDASRQETLEIADAFARAGVQDIVALRGDPPKGQDKFVPHPDGFSSSV
ELIEALAETEMFSIRVGAYPDTHPEAADMAADVDWLKAKLDAGADEALTQFFFEAETFFR
FRDACAKAGIDKPIVPGILPIENWSGARNFAKRCGTHIPEWVEQAFEKAVRDEREDLLAT
AICTELCSDLIEGGVDKLHFYTLNRPELTRDVCFALGISPRVELENVA
>A0A547CBL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium rhizogenes|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
SGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFRDYMKKVRDLGLHEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEIIKRIEGAEDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEMVHDSGVLKGRRPWKHEANRTDALVAERLERIREGKEENQQEMAEAAA
HHPPHQTH
>A0A2M9BWM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Compostimonas suwonensis|TrEMBL
MPTFSFELYPPRSAAAELALVDSLVHLARVDPEFISVTYGANGSSRGASLAVLKELLVLG
IQPMAHLTCVGSSYSEATRLIREFLDSGVRSFLALRGDPPEGTSEDDVFLGDLRSAGELV
QLIHHVQAEREPFSEQDVEGFPGVKRLRTGERVTIAVAAFPNGHPRSRSVTQDLDTLLAK
EAAGANLAITQLFFHAEDYLRFVDQARAAGVTMRILPGIMPVLSSRRLERILELTGEAAP
VELQRRLSVHASPASQAAVGLDYATELSAEVLDGGAPGLHLYTFNRSGPVLAILRELGLI
TTVREPA
>A0A0Q8GYG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelomonas sp. Root662|TrEMBL
MTTPVSFEFFPPNTPVGVEKLKTVVQELGALAPQYFSVTYGAGGSTRDKTLGAVMDIAAA
GFEAAPHLSCVGSTRENIAEILATYRAQDIHRVVALRGDLPSGTATAGEFRYASELVSFI
RETQGKDWHIEVAAYPEVHPQQRYAAKDMQHFADKMNAGADGAITQFFFNADAYFHFVDE
ARRLGVTQPIVPGIMPFHNYGRIAQFAQRDGIEIPRWVQMKMEGFMDDTASIRAFGLDVA
AKLCERLIAGGAPGLHFYTLNQSALTLELCKRLGLDRQSPSPGLPR
>A0A6B3FPX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7982|TrEMBL
MALGTASTRTDHAPTVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSEDWDTDIRYFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LQDDKG
>A0A7Z9S414|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MNRNAPLAIASPLPNDVRVSFEFFPPNTEKANETLWNSIQRLSPLKPSYVSVTYGAGGST
RERTHATVYRLRHETDLEPAAHLTCVGATTDEIDDIARSYWDAGVKHIVALRGDPAEGGG
PYQPHPGGYAYASDLVAGLKNIADFNISVAAYPETHPEATGAEADLDNLKRKIDAGASEA
ITQFFFDTDIYLKFLERARAAGITVPIIPGILPVTNFTRVAEFSDKCGTKVPHWMADLFD
GLDDDPQTRKLVAAGVAAEQCRTLHTEGITDFHFYTMNRADLVYAICHILGVREKREA
>A0A147KEG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermobifida cellulosilytica TB100|TrEMBL
MLGSPTRPAPRPRRISELLATGEPTFSFEFLPPRTPEGERLLWRAIREVECLRPSFVSVT
YGAGGSTRDRTVDVTERIATDTTLLPVAHMTAVNHSVRELRHLIGRFASAGVCNVLALRG
DPPGDPLGEWVRHPEGLTYAEELVRLIKESGDFCVGVAAFPYKHPRSPDPETDTDFFVRK
CRAGADYAITQMFFEPEDYLRLRDRVAARGCDVPIIPEIMPVTKYSTIARSEQLSGAPFP
ARLAEEFERVADDPEAVRALGIDHATRLCERLLAEGAPGIHFITFNRSTATREVYRRLVG
SPRPRAAAVEAARP
>A0A6L7I2X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella insulae|TrEMBL
MAFHHAQHANSLNQSLSELNGDINVSFEFFPPATPEMENILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETDLVAAPHLTLVDASDEELVELAKHYWNSGIRDIVALRGD
LPAGSPKPTRFANDLVRLLKSVADFDISVAAYPEVHPDAPNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSIPSWLHKQFE
GLDDDPSTRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A2V6Q055|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MGGDLPVSLSRGAGGARAAAHARVRAPRRGRRGALRRVRGAVHARARDHRREDPRGGDRG
SGGRAHPPGDQARAGGSRLRESGLRPDAPAARRRLREARRDGRRNGHRASRARWVSTVRT
NPLATAVAERRFCYVVELVASALRREWQVLEAASRLARVPQLVAGSITSYAGGALGQDPI
RVGTAARARGLTPNVHVTCVSQDREGIRKTLEDLHALGLHNVFALTGDWPREGTPIFDID
SVELVRMIAELRRGGMPFHVAVAVSPFKYVEADQLYQYLKLEKKIAAGADLAITQVGWDA
VKFAELRRYLDERGLAVPILGNVYVLGPRAAERMATGQPPGCWVSPELLEAVRVESRAPD
KGLRARLERAARTVAVLRGLGYAGAYIGGTHDADQVQWVIRRADALATQWEELYGELSFG
RSGGFYLYEDPRRSATRRAPRAAPPGDRATAPAAPSSRSTLVPRALDALGRLFPVARDTP
LRRVLRRLFAWIDRRPPLARAVERLELAVKQPVFGCQACGNCVLSWMEYVCPQTCPKQMR
NGPCGGTDMGRCEVLDQPCIWVAVHERATAAGRVDTLRTFVPAPDRSLRGTSSWINYFLD
RDRRPDRDDQDAGRQVR
>A0A2V7HE16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFSERLAEGPLLCDGAMGTVLYARGVPLDACFDVLNLNNPRVVQAVHADYVAAGADA
IETNTFGANRFKLGVHGVEAQLREINRRGVRLARDVRESAGRDVWVLGSIGPLGKYLEPL
GTVTAAEGREAFGEQAEALLEGGVDAFVVETFSDLAEIALAVEAIRAITDLPVVAQMAFT
DEGVTFMGRSPADVARTLRALGVQALGANCSIGSSTLYDVLERMVAEAGGLPLAIQPNAG
LPSRIGERLIYLSSPGYMADYAGRMVEAGARLVGGCCGTTPQHTAAMRETLDRLLPGPRR
VVARAPVTARPAAVETPGLARTLPPTPLARKLQAREFVVTVELDPPRGHTVDKLVQGAKL
LKEKGVEIVDINDGSLGRVRMSVLATALLIRDHTGLDVNMHFTCRDRNLMGIQADLLGAH
ALDIRNILAMTGDPPRTGDYANATAVFDVDGVGLIGILRRMNEGLDATGSSIGDPTGFCI
GAALNPAAEDPDHEIERMHRKIEAGASWLQTQPVYDLEALERFLARAGRIPVPVLVGILP
LHSFRHAEFLHNEVPGITVPDAARARLRDAGESALRAGIEMAQALVAEVRRRHAGAYLMP
SFGRFEVVAEVLDALH
>A0A6I4VDI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. Eser|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPGTSEMEATLWSSIDRLSSLKPKFVSVTY
GANSGERNRTHSIIKGIKDRTGLEAAPHLTCVDATREELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPEMYGCDLVSLLKEVGDFDISVAAYPEVHPEAKSTQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMNTMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAAAA
>A0A0W0CG34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida glabrata|TrEMBL
MSICKTFSDRDGPLISLEFFPPKTESGKRNLLERMERMSALDPLFITVTWGAGGSTSEKT
LELAQIAQRDLNVPICMHLTCTNMDTTLIKEALDACRSYGIKNILALRGDAPIEDQWDDK
TINSSEGPEFRYAVDLVRYIKENYGDEFCIGVAAYPEGHCEGEAEGNEQDPLKDLVFLKE
KIDAGAQFVITQLFYDVSKFLDFEKMFREQISETIPVFPGLMPINSFSLFHRAARLSHAS
IPKAVLDRFPQEIQNDDGIVKSIGVDVLIDIIEEIYSKTNGRVKCFHFYTLNLEKAVAQI
VSQSSTLSKILEESDNEEDQVVSQDEDGDIVLVDQHEENPLKFKRRRQSSSVSADVIFNR
AIINRGKTDRNESSELASKKLVVSISRGSGVLGRDATWDEFPNGRFGDSRSPAYGEIDGY
GPSLKVSNKRAYELWGSPTSIRDLKAVFVKYLEGSIQSLPWCDLGLSPETALIQEELIQL
NYRGYLTLASQPCTNASSSTDKIFGWGPSKGHVYQKAFIEMFVHRQQWKTILKPKLDYYG
RRKFSYYAGDSKGSFETNLDPHSSNVVTWGVFPNSQVIQTTIIEEESFKAWRDEAFSIWS
EWAKLFPRNTPSNTLLREVHSDYYLVSIVHHDFIETDELWDLLLD
>A0A6G1LN51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Teratosphaeria nubilosa|TrEMBL
MDDRITTKLAALPADASYFSLEFFPPKTQQGFSNLHARLERMAQALRPLFVNVTWGAGGS
TSEKSLALAELTQRSLRLTTCLHLTCTNMSRKLVDEALEQAKVLGVRNILALRGDPPRSD
EYRDPNNPLAEEDDSNKDFTWAVDLVRYIRKQYGDYFCVGVAGYPEGHSDQSHPDDQSVG
HDLPYLVEKTQAGADFIMTQLFYDVEAYEKYEKRLRGHESGAFKTIPIIPGLMPVQSYQI
LRRTTKLSHASLPNDILKRLEAVKGDDEAVKRIGADILVEVIEKMRRMHNPGPRGFHFYT
LNLEKVVTQILERSSLIPPATPVATNGDGLTEEAVADEEKDGFLMVEDAKKMQLRRKSST
KNSQSRNRLIVVRDRASSTSSNRTSAYEAFEDEAGVRRDHINGRANTLAISEGEGALGRE
ATWDDYPNGRWGDVRSPAYGEIDGYGVSLHTSVPEAKRLWGHPTTIEDITTSFRRHLEGE
INAMPWSEEALQPETLTIKPQLLKLINKGWWTVASQPAVKGVRSTDPTFGWGPKSGFVFQ
KPFVEFFFSSADWKRLKPILAKDEQITYFAGNAAGDFESSDESSVNPVTWGTFTGKEIIT
PTIVEAESFKSWLEEAFGIWAEWQRVYALGSESSKLLERVRKDYWLVNVISHGYLEEGAL
WDMLISA
>A0A7V2TAQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MTPTVQETTRRAAWSYDAPLPSVRLSIECFPPRGERAAARFWRNLGRLASVEPVFLSVTC
GAGGTGREGTFPLVQEIRRRLGLEVAAHLTCAGHSRAEVDDLARAYWRSGVRHLVALRGD
PPDGAARYEPRPDGYAYAADLVAGLRRIADFEISVAGYPETHPEAPSPAFDLDNLRRKVD
AGASRIIGQYCFDTEKVLRFRDTLQRAGIRVPFVPGIMPIHDFARIKRFSRRCGASVPLW
LERMFCGVPADSPLHAMIAASIAAEQCRRLVAEGFDHLHIYALNRASLTLAVCRLLGGAG
ALSAAA
>A0A345XLW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces armeniacus|TrEMBL
MALGTPITRTDRTPTVRELLASGEQSYSFEFFAPKTEKGERTLWNALRRIEAVSPTFVSV
TYGAGGSSREGTVKNTERIANETTLTPVAHLTAVNHSRTELRNVIGQYADAGIRNVLAIR
GDPPGDPMGEWVRHPEGVTYASELVELIKEAGDFCVGVAAFPEMHPRSTDWDTDVRHFVN
KCRAGADYAITQMFFRAEDYLRLRDSAAAQGCQTPIIPEIMPVTSVAQIERLAELSNASF
PSGLTDRIHAAKDDPAAVRSIGIEYATELCARLLSEDIPGLHFITLNHSTATLEIYENLG
LHRQSQG
>A0A4Y9QBA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. CT_GayMR16|TrEMBL
MNGTVRELLASDRPTWSFEFFPPKTPDGAAQLWTALRELERLQPSFVSVTYGAGGSTREG
TVSVTERIATETTMTPLAHLTAVDHSVTELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WLAHPQGLNYAAELVELIKSMGDFCVGVAAFPERHPRSPDFDSDVEMFVRKCRAGADFAI
TQMFFRAEDYLRMRDRVAAQACDVPIIAGVMPVTNAKQITRIVQLSGQAFPADLAERFVE
LDGESAEEKAAVRAFGVEVATELCRTLLAEGVPGIHFITMNRSTATREVYANLAPEAAPT
R
>A0A2M6YDQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydromicrobium americanum|TrEMBL
MKVINLYKGNKPVFSLEVFPPRNGESLGAVLNTIDSLWSFQPAFVSVTGGALGSMRGGTI
AIAAGIKRKYGIEGIPHFTCVNKSKQDIENLLMEMKFNEIENIFALRGDPPMGQKEFIPH
PEGHRYASELVEQIKLLNEGVYILSSIEKDYEASPTNFGIAVAGYPNGHPECPDKKKDLE
HLKIKVDNGADYIVTQLFFDIDVFLEFVENAKKIGIDIPIVPGVMPMNKYGQIKFVSKQM
GIEIPEKLKDKLEAHKDDKDAIKKILEEHTLLMCKKLVEQGSPGIQFFTMDKPEGTEKVL
QELCKEKKRY
>A0YXW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lyngbya sp. (strain PCC 8106)|TrEMBL
MNYFRTACTTPGEFIITAEIAPPKGANPTHMIEMANTLKGRVHAVNITDGSRAVLGMSSL
ASAIILKSHGIEPICQMACRDRNRIGLQADLLGADALGIRNILALTGDPVKAGDHPKAKS
VFDFESVRLLTAIQKLNNGTDWNDKALPHGATDLFAGAAVDPQSPSLSGLKSRFERKLKA
GAQFFQSQLITDFDCLDKFMTEVAAGIDQPILAGIFLLKSAKNARFINKYVPGVNIPEST
IERLEKAPKPLQEGVMIAAEQVKLARQLCRGVHLMAVKREDLISKILDVAGIPPLY
>A0A4R2UIF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. (strain PP-F2F-G36)|TrEMBL
MSGFPSASGDLLPGHSSRGRLEQVLRRGEFAVTAELNPPDSADPEEVYARAAVFEGWVDG
INAVDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQGDVLGAAAMGVANILC
LTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDHAKFLSGRKLTAPPRVFLGAAINPFA
PPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFRAYMEKVRDLGLHEHCHILVGVGPMASA
RTARWIRSNVPGVHIPDAIIARLEGAADQKKEGKQICIDIINEVKEIKGVSGIHVMAYRQ
EEYVAEIVHESGVLKGRRPWRREQDPADAGVAERLDAARGGEMQDQESLAETAAKRPH
>A0A286FEU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma fluviale|TrEMBL
MTKITEHIKAANGKPIFSIEVIPPIKGDNLKSLLDNIEPLMEFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFSREETEDFLIDLHYLGID
NALVLRGDPAKPFSTFKAKENGYSYASELVEQVANMNKGIYLHEEDTALAPSNFCIGVAA
YPEKHFEAVDHDIDFQYLKQKIDKGADYIVTQMFFDNAKYLSFVERCRQEGITVPIIPGL
KPLSTRKHLQILPKLFHLHMPEDLVRAVEACENDQQARQVGVEWCIQQCRELIEAGAPVM
HFYTMGKSDNIMKIAREVF
>A0A1G1R4H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium RIFOXYC2_FULL_45_15|TrEMBL
MTFKEKIQAGKFILTSEVGPPKGIESGRILEDVELVRGRVDAINVTDLQSSVMRLGSLAV
SIRLKEKGFEPVYQVTCRDRNRLALQSDILSAANFGIENILALTGDHPKLGDHPHAKAVF
DIDSVQLIQVIRRLEQGLDMAGKKLEGVLPKFCVGAVVNPGSDPLEPQIMKMEKKIDAGA
EFFQTQAVYDLKSFENFLSKTKHLKTTVIAGIVLLKSAGMAKYMNENVAGISVPDNLINE
MRDTKDKQAQSIEIAARLIKELKPMCQGIHIMPIGWDKLVPKVLDAAGL
>A0A1I3SIK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia megapolitana|TrEMBL
MNPLELSFEFFPPKTQEGVDKLRLTCVQLAALKPKFVSVTFGAGGSTQQGTLDTVVNIAK
EGLEAAPHLSCIGSSRENLRAILNEYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRSEFGDWFFIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFYNPDAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARQLESFGDDRDAIKAFGLDV
VTNLCRRLIDGGAPGLHFYTLNGAAATKSICERLGT
>A0A2V7I1V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
ALNPAAAEPQQEMERFLAKAEAGARWAQTQPVYDLEPIERFFARTRPPIPIVVGILPLHS
SRHAEFLHNEVPGIAVPEPVRARMRDAGERGLRAGIEMAQSLLRDVRSRYMGAYLMPSFG
RFEVVAEVLDALH
>H6RDT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Flavobacteriia bacterium|TrEMBL
MKVTEHIEQAQGKTLFSFEIIPPKKGSSIQELYDNIDPLMEFNPPFIDVTTSREEYIYIQ
REGLLEKKITRMRPGTLGICAAIAHKYNVDTVPHVLCGGFTKEETEYLMVDCHYLGLDNV
MALRGDAMKEQQYFEPTKGGHNYALGLVEQLSDMNCGKYLNDRVESKHCADFCIGVAGYP
EKHLEAPSMKNDLRRLKQKIDAGAHYVVTQMFFDNQKYFEFVKMAREEGIDVPIIPGIKP
LAVERHLQLLPQVFNLDLPQSLIEAVEGCKNNKEVREVGIEFCIEQSKELMEFGVPVLHY
YSMGKSDNIKAIASALF
>A0A8H4KIX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium austroafricanum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFENTLRDHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPNHLLARLDAVKGDDERVKMVGVDIVSELIDKVKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRHSRRHSSV
ASDPHNRVIVGDRPAMYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSIHMSVTQAVKLWGHPKTRQDINDLFVKHIQGELSAIPWS
EEELLAESSTIQPHLLQLNRKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQNVVCFYASNARGDYVSSDNGDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRASESEKLLSGIKDEYWLVNLIHHD
FVEKDALWQVLSS
>A0A3R9F065|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MSLLAQYFAQQQFCVLVEYLSAHQAQWSVKTEFAGFPAAMTLADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDAKTQGQKNLLLLTGDKLKQHCYSHDLEPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMAAL
QDAHAFLARHQYAQKILACVMPLTLARAKFMLKHEVAGIVITPHMLQVLQQEKEQGLSDR
VYVRCALQILMCRHLGFAGVHLSACHQPGEQLLLESYIEEYRHLSFAECEQLWNTLWQVQ
TGTEFHPKLAYYSRPATSSQIIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDRSRAKQ
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSIKARLAKAVGQTKILKEKLIPTVSIAVRGTSSWKNWYVEAAG
>R8LAN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus HuB13-1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPNFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A401P6U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scyliorhinus torazame|TrEMBL
MVNEEQSGMGQVFKSDDRFSDGSQESSRSSTPSPDADGLQEKIRRHIESGDKWFSLEFFP
PRTSGGAVNLISRFDHMAVGGPLFIDVTWHPAGDPGSDKETSSMTIASTAVNYCGLETLL
HITCCNQTKDQITQHLHKARHLGLKNLLALRGDPMGDEWKTEEGGFNYASDLVKHIRSEF
NDYFAICVAGYPTGHPECKSYEEDLRHLKLKVEAGADFIISQLFFKPETFLSFFKDCRAM
GITCPILPGIFPIQGYHSLRQLVKLSKLQVPQEIKDIIDPIKDNDAAIRNYGIDLATDMC
KVLLESGLVPGLHFYTLNREVATVEILKRLRLWTEDPRRALPWTISANPKRKIEDVRPIF
WASRQKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLNSNCSKEELLKMWGEELV
DEKSIFDVFTAYITGQSNSNGKRVTCLPWNDEPLALETSLMKGELEKVNQMGILTINSQP
NINARPSADPIVGWGPEGGFVFQKAYLEFFTSAENIPTLLKVLKKYKTRVNYQIVNVKGE
NINNAFDLQPIAVTWGIFPGREIIQPTVVDPISFIYWKDEAFALWIERWAKLYPTGSPSW
QIIQDIHDRYYLVNLVDNDFPFENCLWQVIDDLFRLKASEKTCGSPTCELPVKP
>A0A1L8X7A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus raffinosus|TrEMBL
MSSALSFEVFPPNTQIGTEKLFKTLKELQQLEPDFISVTCSNNRQTIEETTLKVADYIHR
KLKVPTIAHLPAAYLSQSQLAELVKRLDQIGINQILALRGDILPDLPPKKDFVYASDLIQ
YVKREAPHLHISGACYPESHPESLNRIEDIKQLKHKVAVGCEQLITQLFFDNDLFYQFQE
SCYLADIKVPILAGIMPIVNRNQALRLIKTTNTKLPRKFLAILEKYEHDPVALREAGLAY
AIDQIVDLTTQDVSGIHLYTMNNAEVAKHIYHNTKNVLNGQWKAG
>A0A8J2EHA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amoebophrya sp. A120|TrEMBL
MAKIIDLIREDDEPDRPFFSFEFFPPKTDIGTVNLYERIERMSRVNPLWIDVTWKPETKG
QTLEICRIASQFYGVNVMMHLTCANATKRSIRRALECCKQAGIKNLLALRGDLAPTDEGT
TSPSTSGPGPVGSVNSSIPSTTGQGNDDFQKLKGERELSVNDLSDCSSSEERTAAKDKGI
TATQKPDFEHAVDLVRFIREEEGNYFCIAVAGYPEGHLEAASFEQDMKFLKEKIDAGADF
VVTQLFYEVSAFVKFVRALRKIGVDTEETPVLPGIMPIQSYNGFCRMTENCKTQVPDDIV
QELELIKDNDQMVKNFGVEQCIKMCTELLTKNPDVKPRGLHFYTLNLETAVLRVINGMEL
FDWWRNNRKLPWRPGFRSSGNLCTSSGHGNTAGSTSNASPGGQHHQNQNDRDVISQSPPA
DHATKLHHQTSNEESVRPIFWANRPQSYLYRTASWDDFPNGRFGNKDSPAYGDFSTQFVS
YSKESLTKVRQDRRNMWGEELSNGLKSIATVFVKFLQNDPKVKKLPWNTEAPTKETNFIL
PQLCKLNLLEIFTINSQPRVNATLSNDPFVGWGPPGGFVYQKGYIEFFISPTNLHYLLEK
IDEEKLKSWRYTAINRSGSKKYTNNSSNTICAITWGVFPSSEVIQPTVCDDVSFEAWKDE
AFELWDLWSSIYPENSPSKLLISQTIKQTWFLMNIVDNDFVSGDLFSTLVELMDANAAKA
WRQNCVVSNPSSTSSTTSSTYTTSKR
>A0A8C3Q0I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chrysolophus pictus|TrEMBL
MVNENQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVHGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETSLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPPQQ
>A0A699Q1U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tanacetum cinerariifolium|TrEMBL
VEHIRKSYGDYFGIAVAGYPEAHPEVIESNGLATPEXSIPKGS
>A0A8J7CCJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfomarinibacter sp. MAG AM2|TrEMBL
MPDGSSLDLAAHEHPQAVLDIHLAYIEAGAELIETATFGSSRPRLERVRVGDLTETVNAT
AVKLAREAREISGKDVLVAGSMAPLAGVLDLDEPEGRAMIPVAHAEQAAILAGRGADLLV
LETFFRVDELAIAVEAVRSVTDLPLIAMMTFAHERPPHPYEEQGCLLDELADLDLLALGV
NCAPGPMGAIEILRRVRQVRLPLAASPNAGTLVRREGRILMPPATPSYLARFARQAVGLG
TAVVGGCCGTGAEHIRAIAEAVRSLTPERRAKTTVAAPDIAEAPEAVRPSSALAAKLARG
RFVRLVQLDPPKGTNVDAMLEAAAAIAAHPDIDGVDINSNPLARLRMDPLFLGQLVQQRT
GLEAVPHITPRDASLMGLQSQLLGAWRGGIRNLLAITGDPSQLGDFPGVHDVYHVDIFEL
VRALSRMAEGFDCAGNRIGDPPGFLIGVAVNPAADDPAKEADRLRRKIDNGAHFAMSQVC
FDWEAWDRFAELFNGELPIPTLTAVWPLRSLKMALRLHHEVPGIFVPDDLLAALEEAGAD
AARVGYERAVQMLREAPDRAAGAYLIAPFKQPQAILPVIDDAAGLGVWLLVAVLVGKMVA
MAVSLGAGFMGGNVFPLIFMGGTAGVIVSLVFPDIPYALAVSCMLAAVPGSYLRAPVSMA
FIAAIAMSLGPEAVAPVSVAIATSYLLVAVTRYLLSQRRAATPVQ
>A0A7G5EEE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas piscis|TrEMBL
MSFPISFEFFPPKTPEGAEKLRVVRQALYARKPQFCSVTYGAGGSTQEGTFGVVKAILEE
GFDAASHFSCVGATKQTVRAQLQQLKDMGVKRLVALRGDLPSGYGLGGEFHYASDLVTFI
RDEFGSDFYIEVAAYPEMHPQARSPEADLQAFLAKVKAGADSAITQYFFNADAFCKFQED
LQKRGVDLPVIPGIMPITGSTQLLRFSDACGAEIPRWIRLRLQGYGDDVASIRAFGLDVV
SQMCEDLRRRGAVGLHFYTMNQSAATLAICDRLGL
>A0A6I0M216|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides thetaiotaomicron|TrEMBL
MRVIDLIHNSEKTAFSFEILPPLKGTGIEKLYQTIDILREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLFWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEALKCKNDKEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A553JUN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella hanedai|TrEMBL
MSFNHAQHSTSLNQSLAELNGDINVSFEFFPPASPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETNLVAAPHLTLVDASDEELKELAKHYWNSGIKDIVALRGD
LPDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDARNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFKQLKRFAGMTNVGIPGWLHKQFE
GLDDDPVTRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>I0QQY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. M24T3|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPDELRQIAQDYWQSGIRHIVALRGD
LPANSGKPEMYATDLVHLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPRWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPIPASLA
L
>A0A1M2YKM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. 63-7|TrEMBL
MSPDINPFDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNGKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRAYMDKVRDLGFDEKCFILVGVG
PLASAKTAKWIRSNVPGIHIPDAVIKRLEGAEDQKKEGKQLCIDIINEVKEIKGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWTPEASPTDALVAARMNQMRQGTEQNQQQLAEIAAH
HPH
>Q1YUX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium HTCC2207|TrEMBL
MNTDTPDLSFEFFPPKTEQGKTKLATTRQELGKFNPEFFSVTYGAGGSTRATTADQVAAI
QADGFDVAPHISFGGNSETEVLELLNSYKAAGVRHLVALRGDLPSGMGGAAQLVHANQLV
EFIRQHTGDHFNINVAAYPEIHPEAESYSKDVFWLGEKFKAGADRAITQYFYSADAYLKF
VDECAKGGINQPIIPGIMPLTNYANLIRFSDSCGADIPRWLRWQLKERSDNMDDLVSYGI
DIVSELSQKLLDGGAPGLHFYTMNQWQVTGTLCRNLGFAENT
>A0A656TXG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL S-444|TrEMBL
MSARPTPYPERPVPAPVTGGGLAELLRRVRYEVLPAKATEDKVLAHVPADVPVTVTASPA
KGLGPTLDLATRLAGHGYRVVPHVPARQVSDAAHLADIVDRLVAAGIEDVFVPAGDADPP
AGAYDAALPVLRRLGELGSPFAHVGITGYPESHPLIADDVTVQAMSDKQPHATYIVSNLC
FDPATLRQWLARVRRRHVVLPVHVGIAGPVERAKLLSMATKIGVGESAKFLTRHPSWFLR
FAAPGGYSPERLLRRSAPALGSPEAAVAGLHLFTFNQIAETERWRRAMLERIGG
>E4Q8M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldicellulosiruptor hydrothermalis (strain DSM 18901 / VKM B-2411 / 108)|TrEMBL
MKKSFREFLKEQSTVIFDGAMGTELLNRGFSLDFPLEWANVTRPELVKQIHTDYILAGAS
SIETNTFGANECKLKVFGFENEVERINRSAVRIAKEAAENKVYVIGSVGPLGKPVGSGFE
IDARRAKEVYKRQLYFLLDEGVDAIIFETAASTHEVQIAIEALKELNDKIPYIIQFSFTK
DLSTIYGEDIYRVIEFLKSTDADVVGLNCGNGPQKTLEALKIFSQHLKGPFSVQPNAGYP
QLVQGRLIFSTSAKYFASFVPEYIKLGAKVVGGCCGTTPEHIKAIKEKVKEFSPSIEVEV
SERKEEQKAVLKDTPSELSQKLGKKFIFTVEISPPKGIELEKTKEGVKLLKEAGADTVNI
ADSPMARVRISPIALAHILKEELGMESILHFTCRDRNLISLQSELLGAAALGVKNVLALT
GDPPSIGDHPQAKPVFDVNSEGLVLILSRLNNGTDYMGNPIGKATNFTIGVALNLNADDL
GKEIEKLKHKIENGAHFIETQPIYDAETLERFLEKVDFTLPPILGGILPLRSSRHAEFLH
NEVPGITIPDKIRERMRSSKEPAKEGVEIACEIVDRIKHMVSGIYIMPPFEKYEMAVEII
RNFRY
>A0A7N6B5U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabas testudineus|TrEMBL
MVNQVQRGGGSWQSCKSDSSGASNSGGESSKESSRCSTPVLDADRLDRLRDKMRRRMESG
DRWFSLEFFPPRTAGGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKISGHLAKAKHLGLKNIMALRGDPIGSDWEEEEGGFNYAV
DLVKHIRSEFDDYFDICVAGYPTGHPEAQSYDEDLQHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRANGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGRVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLQMWGEELMNEESVYEVFTCYITGQPNRSGHKVMCLPWNDEPLAPETNLLNDELEKVNR
RGVLTINSQPNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSSENVDALLQVLKKYEPRV
NYHMVNVHGRNMTNATDLQPNAVTWGIFPGREILQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWQVISDMFELLDAPPEPLTDRAV
>A0A851D9W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Todus mexicanus|TrEMBL
MVNETQQPGSASSSSRSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNVMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDVCVAGYPTGHPEAESYEADLKHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKRYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A501WJI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amaricoccus solimangrovi|TrEMBL
MAETATRALPSLSFEFFPPHSPEASLRLWRSVERLAPLGPDFVSVTYGAGGTTRDRTYAA
IQAILDRARLDVAGHLTCVGATREETLGVARNYARLGLRRIVGLRGDPPKGETRFTPHPG
GFAGAAELVAALREAGDFEISVAAYPEKHPEAESLESDIANLRRKLEAGASNALTQFFFE
NEDFLRFRDLCAKAGITAPIHPGILPVENFRKMVNFAARCQARVPAWMHEAFEKTETAED
AYSLSIELARKQVEALMAEGVEHLHIYTLNNPNLSYDLCVSLGYREIPLAKSGAA
>A0A7Y9BDM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. EB106-08-02-XG196|TrEMBL
MSLLEKLEKQILIADGAMGTLLYSFGKDSCLEELNLSHSEKIQEIHKAYIDAGADVIQTN
TYAANYLKLQRYGLEDSVKEINAAAVENAKKAAQKNAYVLGTIGGNRGIKSNTVTIEELR
RSFREQLYCLLLEGVDGLLLETFYDLEELRTVLSIARKETNLPIIAQVSLQEPGILQDRT
PINEALTSLENLGADVIGLNCRLGPHHMLKSLEQIELPAHAFLSVYPNASLPAYTDGKFH
YEGDADYFRKSAKAFRNEGVRLLGGCCGTTPEHIRAFALELKNSEPVTEKVVKFKQRVVV
ESNAPKRDFQPLEELVKEKPSVIVELDPPRKLDTTKFFEGAKALKDAGIDAITLADNSLA
QVRISNESLGYLVKKELGMRPLIHISCRDRNIIGLQSHLMGLHTLGMNDVLAITGDPARV
GDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTAFSIAGAFNPNVRSVEKAVKR
LEKKIEYGADYFISQPVFSEEKLIEVYEHTKDLKAPIYIGLMPLTGSRNAEFLHNEVPGI
KISQSIRDRMSALNDQPLLAAREGIEITKSLIDTALDLFNGIYLITPFLRYELTTELAIY
AKQRASQVRGNNYVESSIK
>A0A1H0V7R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia sp. 25mfcol4.1|TrEMBL
MTDRYYSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRDILKTYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQARSPRHDLDNFVRKVKAGANSAITQYFFNADAYFRFVD
DVRAMGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDKESIRAFGLDV
VTALCERLLASGVPGLHFYTLNTAGATKAIWQRLKL
>A0A1V5NE60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin397|TrEMBL
MNYLGIDNVLLLRGDPIKTESHFTPEEGGNVFALDLVQQVGSMNKGIFLDEDLRDVDPTT
FCIGVAGYPEKHFEAPSINTDIKYLKMKIDAGAEYIVTQMFFDNSKFFSFVDKCREAGIQ
VPIIPGLKPLTTKKQMTLLPKTFHIDLPDDFVKALENCETDAQVKEVGTEWCIAQSKELA
QHKIPCLHYYTMGNAELIRRIASNVF
>M1E654|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobium narugense DSM 14796|TrEMBL
MNELRIKERYKNERTGFSLEFFPPKEKEHEEKFKETMRKYIELKPLFASITYGAGGTTQD
KTFEIVKFVNSLKAFAVMPHLTCIGATKDSVNFLIKKYDDLGVFNILALRGDPPKNVENF
DISKGEFKHAIDLVKYVREYFDHFSIGVAFYPEGHAQASSFEEDFEHCIEKMKLADFAIS
QMFFENSYFLRYRDLVAKRGVDITLVPGIIPIGNFEKIKEFAKFCKVEIPKRLEDIMSKA
SSHEDMKKAGIDFATQQCAELIKEGVKFFHFYTLNQFDLCSKVIKNFW
>A0A1G1HLB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium RBG_16_43_8|TrEMBL
MKIRDVIKEKAAGISFEFFPPKSVEGRQGFMKVVHELKKYDPLYVSVTYGAGGSTQDRTF
NTLKWIKEETSLNVMSHLTCIGATRTSMEGLLKSYAENGIDNILALRGDPPKNIPDFDQI
KGEFKYAKDLVAFVKGYKSFSIAVAVYLEGHQESPNIEKDIEYTKQKVDAGADFAITQMF
FDNSYYYGFMDRALKAGINIPILPGIMPITDFKKVEEFANFCNATMPKEIKKKMETVLDK
PEDMRKMGVELAIKQCEDLMRNGVKYLHFYTMNKLETVSEIVEGLGRFHPSL
>A0A3M4L280|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. actinidiae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A256FFV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella grignonensis|TrEMBL
MGFYGLSRRSDIGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLKPEFVSVTYGAGGSTR
ERTIRTVARILKETDIEPAAHLTCVDATREEVDRAAQEFAALGVNRFVALRGDPASGIGE
KYVPTQGGYQNGADLVGGLRKLSDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVSNFCARSATHIPAWLAERFD
GLDKDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKIDAEL
EVA
>A0A4R5NQN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Secundilactobacillus malefermentans|TrEMBL
MKLTEVFKQKTVFSFEVFPPHGKTPLVKIKQTLEELEDIHPDFISVTLGAGGTGKRDSTV
EIADLIQNDLHIPAVAHIPGLYQSKKDVQGLLDQFAAHHVTNIMALRGDRVPGHEPVGDF
DHADDLVKFIKQNGDFDVIGACYPQCHQEAKDIATDIRFLKQKVDCGTEHLISQLFFDNQ
CFYDFTKQARQADIIVPIEAGIMPVTNQKQIARIADISGTPLPEKFLTIMNRYVDNPEAM
RDAGIAYAIDQIVDLVAHGVDGVHLYTMNHSQVAQRIWAATKTLFEASTTKPV
>A0A0B0SER7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus sp. (strain 2.9)|TrEMBL
MKIRDLLRSRQGPLFSFEFFPPKTAEGEEALFRTMAELKAFRPAFVSITYGAMGSTRERS
VVWARRILGLGLTPLAHLTVAGQSRAEVEEVLRRFVESGVENLLALRGDPPQGERVFRPH
PEGFRYAAELVALIRGRYGDGISVGGAAYPEGHPESESLQADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIAIPILPGIMPITNYAQLRRFTEVCGASIPGPLLSQLERHQ
DDPKAILEIGVEHAARQVAELLEAGVEGVHFYTLNKSPATRMVLERLGFRPA
>A0A0R1MNU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus hordei DSM 19519|TrEMBL
MDKILTKPHLSFEVFPPSASIKNPKIYQTVQALGDLHPEFISVTCNNKQLDFEDSTLKVA
SYIENELQVPGVVHLTARYFDKKQIDYILAELKKRGISNILVLRGDLVPGKVPKSDFKYA
SDLIDYIKQRDSTFKIFGACYPEGHPESPNKVTDIRQLQTKVAAGYDCLITQMFFSNETF
YQFEEDCALANIDVPILAGIMPIVNRSQALHVVQNSASFLPKKFVAMLDRYQTNPAALKA
AGLAYAINQIVDLVTQNVDGIHLYTMNHPDVARHIYQETQTLFAM
>A0A081MZQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endozoicomonas montiporae|TrEMBL
MTTSTLPISFEFFPAKTEEGAKKLEHTASQLADNKPEFFSVTYGAGGSTRDRTLDTVTGL
SRVTGVNTAPHLSCVGDTKEELRTLLKQYQALGINRLVALRGDLPSGMGGFHGELQYANE
LVSFIREETGEHFTIEVAAYPESHPQAPNFEQDLLNFKRKVDAGADSTITQYFFSAEGYF
YFRDRATALGVDIPIVPGIMPITNYTRLARFSDACGAEIPRWIRKQLEAYGDDVKSIKQF
GEEVITKLCERLIAEDVPGLHFYTLNQAAPVQAICRNLGL
>A0A7S1Q0V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neobodo designis|TrEMBL
MATPQPKASEILRKNAAEGKQSFSFEFFPPKTEAGMDKLLGSMADFQKQGPVFIDFTWGA
GGTTSEQTPALCKKCKEMGFIVNMHLTCTNMPQGKVKEALDLCKENGITNLVALRGDPPA
GQEWKASEDGFNCALDLVKYIRANYGDYFSVAVAGYPEGHPDRIDAESGKCADFDAEIAY
LKEKIDAGGEYIITQLFYDTDIFLRFVQTCRANGITVPILPGMLPFTAYGGLQRMVGLCK
TYLPDELKAKVEELKEQPDAFKQLGIDVTAEQCKKILASGACNHLHFYTLNNSYSTFKVM
EQLGWLKQ
>A0A7K7CB40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphelocoma coerulescens|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLRDKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A2H5A3E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula taiwanensis|TrEMBL
MALGTHAVSNSQGVQTLLTSARFELMPFESFDEEITHLPDDATIAITTSPQLGIEKTVEK
TEQAAAMGYDVVPHVAARYVEDRAQLEAIAGRLDQAGITDIFVPGGDREEPAGEFESALD
LLEALADTEYDFEEVGITGYPEGHDFIDDETLAESMARKAPYATYIVTQLCYDPDAVLEW
VEEIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDNDYNIRGIHIYTFNQTPDTEKWRHKRLDS
>A0A7D6I8Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas chlororaphis subsp. aurantiaca|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLSQYKAAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQTFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A5M7BAZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora hirsuta|TrEMBL
MAVVDRLRTERTTFSVEFFPPRDDAEERVLWRAVRELEPLDPAFVSVTYGAGGSSRDRTI
RTTGRIAQETTLTPMAHLTAVDHSVAELRNVIGWYAASGVQNVLAVRGDPPGDPNGEWVR
HPEGLEYAEELVRLIRELGDFCVGVAAFPHGHPRSADLDVDADHLARKIRAGAGFAIAQL
FLEPEYFLRLRDRLAARGCDVPLLPGVMPITTPRVLAKFGELAGVPVPSAIADQLLPLAD
DPAGFRQAGVDVVTRLCERLIAEGVPALHFYTLNRSKATRQVVAALGL
>J0L549|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus mali KCTC 3596 = DSM 20444|TrEMBL
MSTFNYSLELLQNNSNSKEQALNKLAPEFISIAYTNHTLSFFETTFSTALALKKATKNKT
VIHLPASSFTQEELDKLVAALQKSTIDSALILSGKKINKNSAYTSALELTQFLNNKLPDL
NILYSCHPEAITSEISLQNELSLMKTKEAAGCKIFISQIFFDNTMFVQFVNHCRHAGIKA
QIRAGIMPIVNKKQLTFVKNILKLQLPNSFERASNDIQLKKIGVRFALNQINMLKKQGIT
DFHFFTMDNLDTVKLLIDGVL
>A0A5F0GFF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT1-2-1|TrEMBL
MTETTTTTRTRGRRIPFSFELYPPKSEAASTALTHTIDRLAAAGPDFISVTYGANGSSRT
SSLDVLRYILDATGVDPMAHLTCVGSSAAEASRLIREFLDAGVRSFLALRGDPPQGVDEG
ETFLGDLGSAAELVQLIHRVQAERVPYRETVIPGLPGARAVKTEREKVRIAVAAFPNGHP
RSRSTSQDIDTLLAKQAAGANLAITQLFFHADHYLSFIHRAREAGVEFPILPGIMPVTSP
NRLRRILELSGEEEPADLSIQLQVEPTEQGQREIGITHAVGLARELIAGGAPGLHLYAFN
QHETVLAVLEGCGALPASSPHAATQITAAQRTAHRPTSTGHTHPVKESA
>A0A0Q5AW14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. Leaf294|TrEMBL
MTRPRFEIIPTDDIGEKTARAFADPSRVTLTVTSLPKHGTERTISCALDLAGRGFRVVPH
LAARNIGGRSDLERTLGRLLDAGIDEAFVISGDARTAAGAYTTSLELIRDTVEIAPGIAL
DIAGYPEGHPHLSDESIERHLRERAPYVRSIVTQMCFDVDAVVGYADGLRDRGITAGVWA
GVPGPVERTRLLSLGARIGVGSSLGFLKRSSSVAGGLLRGRRFDPTAFVGRLEAAAGDRL
EGLHVYTFNELDGVEAFTS
>A0A5S4SY76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp. Z1|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPEFCSVTYGAGGSTQAGTFTMVRDIQNE
GVGAASHFSCIGATHEKVRAELNELKAMGVKRIVALRGDLPSGYGLGGEFQYASDLVAFV
RQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VRALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A0S9DBB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Leaf234|TrEMBL
MTVLPDLPVRVEVIPGENLVEKLRAYLPAPATVTVTCLPQHGPRAAVDLAVGLAAAGYTA
VPHLAARSVADRTELGDHVGRCLDAGITDVFVIGGDAPVAAGPYVWSGALMEEVAGLSGG
ALRMGIAVYPEGHPATAEDALLTTLRSKQDLASWCVTQLCFDPDTVRTFPAKLRAEGITL
PVWAGIPGPVRMSRLLRLAGSIGVGQSLGFLKRSAGGSNSGSVLRQLVTSASYDPAPLVE
DLDGAGYAGLHLYSFNDLAELADSGLVGPVAPGS
>A0A1H0LFY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus singaporensis|TrEMBL
MGDGQETSNSTTGKNYRLIAEIDPPKGVDLEPFIDTALQLRGRVDTTRVTDSEHAIMRMS
PLAPCVSLMDRGFEPEMTITGRDRNRISFQADLLSAAALGINRIVIKKGHDPAEGDQPVA
RSSGDLDLVTMLKCAAALNSGKDLGGESLTGTPTFDIDVAIDLSDDVNLNRERAEFFRQM
AGYGVKSVTLGPTYDLNIIEPFIPFAEETGIKLNTSVMFLKSVTMIRYLNNLPGVPSIPQ
EYLKKMMDAPVKKDAGMEVAAGFIKEVAPLCDGVVLLAIGWRDRLSQFLDLIGR
>A0A248VGX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia aromaticivorans|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRVQLATLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRQDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCGRLIDAKVPGLHFYTLNGAAATKAICERLKT
>A0A7D6YW22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPLGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A1F2RA19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium RIFCSPLOWO2_02_FULL_64_15|TrEMBL
MTNPLGDALAAGRFCYVVELVASRRKREAQLFEIASGLARLPEVVAAGITNYAGGAMGHD
PLRIAVGALARGLTPNVHLTCVGQDRQGLRKTLEEMHALSLENVLALTGDYPKTGDRPPV
FDLDSVQLVRLIDEMRRGGMDFNIGVAVSPFKYSEIDCVYQYLKLEKKIEAGADVAITQV
GWDARKFEELKRYLDRRELHTPLLGNVYVLDLKTAERMAKGGPPGCWVSPELLGAVRAER
QEKDGGRHARLDRAARTVALLRGLDYAGAYIGGIHDSDQISWIIRRAEELVPQWKELAAE
LQYGAPGGFYLYDRPAWADADAPHRTAPPSPTAPKDRPRRELVPRILDLLGRTFPVRRDT
RLRRTLTSIFAWIEGRPRLAAAFERAELALKKPLFGCQACGNCVLGHMEYVCPQTCPKQL
RNGPCGGTHRGQCEVIPDNQCIWVKVYQRAKEAGEVESLKVYIPPPNRELQGTSSFINFF
LERDSLSAPLNRDRRRGARDNDRIGMAQHRPSSGSSSSSSAPFE
>A0A4R8XNU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TmT2-59|TrEMBL
MSTTSEPDCGRIPFSFELYPPRSDAAATALHATIATMASAGPDFISVTYGANGSSRSSSL
EVLTHILKTTTVDPMAHLTCVGSSSLEASRLIREFLDAGVRSFLALRGDPPEGAGEGEAF
LGDLGSAAELVQLIHRVQAERVPYRETVIPGIPGARAVKTEREKVRIAVAAFPNGHPRSR
STSQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRARTAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIQLEVEPTREGQREIGTRHATDLARELIAGGAPGLHLYAFNQAD
TVLAVLAGAGLIKPVLG
>A0A7Y5AMH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rheinheimera lutimaris|TrEMBL
MAFANAQYLEAINRNLQDVEGKVNVSFEFFPPKTPQMEQTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDATKDDLIAIAKDYWQNGIRHIVALRGD
LPPGSTSKPDLYAADLVEILRSVADFDISVAAYPEVHPEAPNAQFDLLNLKRKADAGASR
AITQFFFDTEKFLRYRDRCAAIGIDVDIIPGILPVTNFQQLKKFAGLTNVAVPQWMHKAY
EGLDNDATTRNLVAANIAMEMVKVLSREGVDHFHFYTLNRSELSYAICHLLGVRPQIAV
>A0A7W9A4Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas halotolerans|TrEMBL
MTSLAEARALLLSPLGPVARAGSNRNAVNVSFEFFPPKSDEAEATLWKAIRRLEPLNPGF
VSVTYGAGGSTRERTHRTVQRILAETGLAPAAHLTCVEASRDEVDSVVAEYKAAGVRHIV
ALRGDPPGGNGIGGVYQPRADGYANATELTAAIARHGDMEISVGVYPEKHPESPSIDHDI
DVLKAKIDAGATRAVSQFFFDIDAFLRFRDRVRAAGITLPLTPGIMPVSNFNGLKRMSAA
CGASVPDWLAAHFDGLDDDPETRRLLAASVAAEMCARLQEEGFADFHFYTLNRADLVYAI
CRVLGVREAVS
>A0A2P9AXR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium delmotii|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHQVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A1V1I3H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Romboutsia ilealis|TrEMBL
MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAANVTDFQSAVMRTTSLA
TCKLLKDVGLEPVLQITGRDRNRIAIQGELLSAGVFGIKNMLALTGDHTVVGDHPQAKGV
FDLDCIGILQTAETLMGGKDLVGNELKGSPEFYLGASVTPEYAPIEIQLIKMQKKINAGA
KFFQTQAVYDIEHMREFRKLTKDMDCKVLAGIVPLKSPGMAKFMTANVPGIFVPDEQIER
LRAVGKENWVSEGIKMAGEFIRQLREEDLCDGVHIMAIGAEENVPAILDEAGL
>A0A640UYH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces tubercidicus|TrEMBL
MRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALRGDPPGDPMGEWVKHP
DGIGYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVAKCRAGADFAITQMFF
YPEDYFRLRDRVTAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQQS
>A0A2P8DBK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Taibaiella chishuiensis|TrEMBL
MKVTDHISQADKPLISFEILPPMKGKGIDSIFKILDPLMEFKPAFVNVTYHRAEQIFKKR
TDGSFDRVEIRKRPGTVGICAALMNRYRVDAVPHLICGGFAKEETENALIDLRYLGVDNV
LALRGDSPANEKFFTPHPQGHRYAVDLVDQITNMNNGRYLEDDIVDAGKTDFCIGVAGYP
EKHFEAANMNLDLHYLQQKIAAGAGYITTQMFFDNAKYFAYVDNCKSANIHVPIIPGLKP
ITNKRQLSILPSIFHVDIPNEFASEMLQCKTDAACEQLGTEWLIAQCRELLARKVPVLHF
YTLGKPQVVYNVVKAIL
>A0A5C8FZ55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira aalborgi|TrEMBL
MNSVENFINKLENEKEFTFTLEVTPQAKSDLGYLVEKIKSSNIEKYIDAFIIPDSPFANL
KISPILSSLQLSQRLKTEKPFIITQTMRDKNSIALQNDLIGANYFDIRMVLALTGDPVVN
GNQKQAKGVFEGNSELLIKIIKNLNEGKSAGNFIFKEPLKKIYPFCSINSYSKNDEMLKV
RLSKKTASGVKAIFTQPIYEVETLKKFLNWIDEMPLKEMKLKEKPILFPGFFPVLSYKTA
YFIYYKLPGAYIPEEWLNKLKDASEKSAEEEKKVAFELSSNLFKDMLSVCKKMHIMSMNN
YDFVADLLKHIC
>A0A3A1P4K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantiacibacter xanthus|TrEMBL
MSYAAIHPNWENPASNMVDGYSLEMTAKEIEGLREAAPLIRPNTQIAVTFLPGEELSQRV
EAAVLVRALGFEPIVHLSARRIESEEQLDWYLGEITQKAGVKRVFIIAGDPPEAEGPYEN
SLQIIESGLLEKHGITIVGVGGHPEGHPNNSAEELWVWMQKKIDAVRAHGMTPLVVTQFA
FDDDAIVAWLAEMRERGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGISITN
LIGSAGPDKLVGNLEKKLTERHGRVRLHFYPFGALTASAEWINAYDAKHS
>A0A659UML3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.158.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHEVDAVIQEFTDMGVKRFVA
>A0A7I0RGB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. CGMCC 11546|TrEMBL
MVTKRIMLKLPDISAASLIPASIEASPAQVLGPASLAGIFPRGVRVYLTDTGAASQEKLV
DAATHLRNLGYEPVPHLAARRIPSRVEFEEQVKRLAGEADVTDVLVVGGGVDRPAGPFAS
SMDMLSSGIFDRYGIKKIAIAGHPEGSPDFSEETAIAALRLKRDFGERSDAAMRIVTQFG
FDPARFIAWAEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LARGHSPDSIVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVSRGSWQTRDAGRPAP
ADSMAG
>A0A8G0WLA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. S11A 273|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATAHQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKEDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VEFIRQESADHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVQQLGVTIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVNSIQAYG
EEVITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A7I8DHU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Effusibacillus dendaii|TrEMBL
MYQIHGLREKLQLGKSVVTVELEPPKGADPMPTMLTAKHLRGYVDAVNIADSPMATLRMS
PIALSHIVQQDLGLEAIFHLTCRDRNILGLQSELLGAAALGVRNILTLTGDQPSRGDHPD
AQGVFEVDAIGLVNIAKTLNEGQDLAGKSLNAKTDFFIGGAANPGAEDQEVEFSKLRAKT
SAGVRFVQTQPVFDVETALRYQERVEKEGLPVYVLFGILPLKSGKQARFLNEKVPGISIS
QEIIDRVEAFGREAGVEIAQELYHALKPHVAGVHLYPLNNLQTVYDVLDIRVDQSVAL
>A0A7K8HXM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aleadryas rufinucha|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVHDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A8F7K4W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. 21P|TrEMBL
MKITEHIQNANGKTLFSFELIPPLKGHSIQGIYDAIDPLMEFKPPFIDVTSLREDFIYKE
QENGLLQKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLHFLGIEN
VLVLRGDARKGDSSFVPTPNGHCYATDLLQQVVNMNNGVYLHEHYDNMLRTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGAGFIVTQMFFDNQRYFDFVNGCRAAGINVPIIPGLK
PVTASKQLISLAKTFHIDIPEDLSDAIHDAKSEKDVKEIGIEWMINQCKELVKFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A2R6IZV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QS_5_70_15|TrEMBL
MGHLPDGTEIAITTSPTLGLDATIEWTEKAAAAGYEIVPHIAARYVRDRDQLDEVMGRVA
DAGVTDVFVPGGDREEPEGEFESAHELLVAMEELDYDFEEVGITGYPEGHAFLDDETLAE
AMARKEPHATYIVTQLCYDPDAVVEWIEEIRGRGVELPVEVGIPGVMKYQRLLGISQKVG
VGDSIDFLRKTSGILGFVKQLVGSRGKYTPDDLIGGLAPYADDPEYGIRGVHVYTFNQVP
DTEEWRLAALEG
>A0A1F9US63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RBG_16_66_12|TrEMBL
MPELLAAAKRPIFSFEFFLPKAPEDLDAFVAFVRGIVGLSPDYLTLTYGAGGSARERTIE
TAGRLQRETGLPTAAHLTCIAHTRAEISAILDRLRALGIRNIVALRGDEPKDGTALPPGR
RDFAHASDLVRVIREGGGFRTAVAAYPEKHPESPSPEEDLRRFAEKIAAGGDWAVTQLFF
DARDYFSFVRRAREAGVAVPIIPGIMPVTGYPQLKRFVALCGTRIPPELDERLASIQHDP
QAVVAHGIDWAVRQCRALLDGGAPGIHFYTLNRSHSTAEILSRLRRA
>G5ETW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia mucilaginosa M508|TrEMBL
MTTVHPALSFELFPPRSQASCESLLRTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSTLVDSAHLAGVDIPIIPGIMPVTSLKRLRNLCQMAGMEVPTDLAYALETATSSAE
LHRIGVEYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQSLSELEY
A
>A0A388RAW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp. P-10|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVKAGANSAITQYFYNADAYFRFVD
DARALGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A437MDW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovarius crocodyli|TrEMBL
MQSTLARWLDTPRVAMLPSPAAQPAPKLSFEFFPPKSEKLEADLWACIRRLAPLGPRFVS
VTYGAGGSTRARTHDTVARLARETSLTPAAHLTCVGGTREEVDEVARAYWQAGVRHIVAL
RGDPPAGSARYEPHPGGYAQAEDMVRGLRRVGDFDISVGAYPEGHPVALSAEADLDFLKR
KIDAGATRAITQYCFDTDTILRFLDRCHAAGIRAPIVPGIMPIANFTSLSRFSAMCGASV
PAWLARMFEGLENDPETHQLVAATVAAEQVRVLRANGVDEFHLYTLNRPELSLAVARILG
VRPQQEGKGA
>A0A1V8TVB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rachicladosporium antarcticum|TrEMBL
MSRPAPTVPPNMADDRITTKLAALHRDATYFSLEFFPPKTSQGFSNLHARLARMAHSLRP
LFVNVTWGAGGSTSAKSLALAELTQRSLGLTTCLHLTCTNMSRKLIDEALEQAKVLGVRN
ILALRGDPPRSDEYRAEGAAVGEDEDDSNLEFTWAVDLVRYIKKTYGDYFCVGVAGYPEG
HADTSHPEHQGVGLDLPYLVEKTSAGADFIMTQLFYDVDAFLKYENTLREHESGVFKEIP
IIPGLMPVQSYQILRRTTKLSHAKIPLNVLKRFEAVKSDDEAVKRVGVDVLSEFVDKIKA
RPDVRPRGFHFYTLNLEKAVAHILERSSLIPPYTPTIIEKNGFTSPEGAIAEDESSTSPP
TNGHATRTRRESSTANSAPRNRVVVSRTRASSTSSTRTSAFEAPEDEAGVPRDKINSRAN
TLAISEGEGALGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHVSIAEATRLWGHPSST
ADLSEIFRRHLEGEVDAVPWSEEGLSPETLTIQSQLLALVQKGWWTVASQPAVNGVRSTD
PIFGWGPRNGFVFQKPFVEFFLPAQDWKRLQPILDEDPRITYFASDAAGDSAASDEESVN
PVTWGCFTGKEIVTPTIIEGVSFRAWCEEAFGIWSEWRGVYGKGSPSSKVLDQVRKEYWL
VNIIHHGYLEPEALWETLVKA
>A0A2G1CX08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malaciobacter canalis|TrEMBL
MFETLIQKLQEDKYLTLETTPQHEPIMHNIIEKVKKFDLQNRVDGFSATDNPLAKLKYNA
LFASLRLQQEFKKPVIATMSMRDRNKIALQSDLLGANEFDVRAILALTGDPAKMSDQPHS
KGVFESNSSMLLKMIKSFNYGMDIAGRPFKIEPKQIYPFAVTNSYARSFTSLEKKMHNKI
QNGAMGIITQPVFDVNNAKKLLEIFENAKEDVVGNKKKAQLIFGIFPITKLRTALFLSAQ
VPGIHVPQDWIDKLELANQISEEEEYKVGMQLSKDLFYEIRKLHPKIHLMTANKFDLADE
ILA
>B9JH74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium radiobacter (strain K84 / ATCC BAA-868)|TrEMBL
MLGEFDMSSKNENGQGGIRISFEFFPPKSEEAEAQLWNTVEELSEWEPEFVSVTYGAGGT
TKAPTLSAVRRMIHETPFTTASHLTCVGATREDTHRVIDDFLATGVRRFVALRGDPPTGV
GSAYQPHPDGYANAAELVAALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGAD
RALTQFFFDNDAFERYHDRVRAAGITIPVVPGIMPIQNLTQLKRFAGACGTSIPSWLDDR
FDGLDDNADERAKVAADVAAEQIKDLVRRGIHEFHLYTMNRSPLVSAVLERLGLQRKADA
RAVA
>A0A434A9J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium cupreum|TrEMBL
MKVTEHIENAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
IMALRGDAMKDEQYFIPKAGGNDYAIDLVKQISLLNQGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNTKYFEFVAKAREMGITVPIIPGIK
PIAVKRHLQILPQIFRIDLPEDLIHEVDKCKDNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASRIF
>A0A8E2LVH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli TA464|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6P1DNF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiorhodococcus mannitoliphagus|TrEMBL
MSTDTHRLPIYSVELFPPKTSEGMAKLKREIDRLSAVGPRYFSVTYGAGGTTRERTFETV
DWLRSQGIDTAPHLACIGSTRDEVREILARYRDQGMRRLVALRGDMPSGMGSGHGGDFRY
ANELVTFVRSEFGDAFFIEVAAYPEYHPQSRNPAQDLENFKRKVDAGADGAITQYFYNAD
AYFGFLESCHKVGIDLPIIPGIMPITNYTQLARFSDACGAEIPRWVRRRLEGYGDDVESI
RAFGHEVVASLCRQLIDGGAPGLHFYTMNQSKPVVRLWEELGLPTPG
>A0A2E7E5N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium|TrEMBL
MLIEKIRNRESGIILYGIVPPKLDTDSDRVEEIAAMQMQRIAPLPIDGLVIYDIFDETSR
TPEKRPFPFIETLDGYGYSQNQLANLDVPRVIYRSVGKYSEAELSDYLNHASQDDLLTVF
VGAASKDQPVSMTLPQAYELKQRMAPESLLGGVTIPERHSSKGTEHLNVFNKIQQGCSFF
ISQGVYDLTASKDLLSDYYYHAQENNLPLVPILFTLTPCGSIQTLKFMKWLGISIPKWLE
NDLKHATDILEKSVDISQQNWLELKAYADEKGIPVGCNIESVAIRKLEVEASIELVKRIA
G
>A0A2J6JDU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MSMLEQRLGAQEFVVTTEVAPPKGCDLSEVLATAAAIEGMTAINVTDNQGANMRMAPMAV
AAKLVAAGIEPVLQVTCRDRNRLALQSDLLAASAFGIENILLLSGDHARFGDHPQARSVF
DLDSVQLLQAVTTLKEGNDLAGRPLQGSPSFFAGAAVTPEAEPLELMLQKFHKKVASGAR
FFQTQAVFSTPRLEIFMAEASRCGTPVILGVLLLKSARMARFLNANIPGVRVPDAMIERL
DKASVPLEEGVAIARELVAAARSYCQGVHLMTLGQETRIPDLLT
>A0A0H3C9A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter vibrioides (strain NA1000 / CB15N)|TrEMBL
MTLPPTRRVIGPVARAGERTGRPRVSFEFFPPKTPQMEESLWQAITRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASREEVDEVIREYWETGVRHIVSLRGD
PPPGEGGIGGVYVPRADGYANATELTKAVRAIAPFEVLVGVYPEKHPESPSLEHDIDVLK
QKVDAGATLGISQFFFDLDAFLRFVDKVRAAGITIPIVPGIMPVTNFAGLKKMAAACQTA
IPSWLGNLFDGLENDAETRRLIACSVAAEMCAKLQEQGFEDFHFYTLNRADLVYAICRVL
GVREISPAASEVAA
>R5L0B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:678|TrEMBL
MKISEILKSRKVTVSFEVFPPKEWSKIENTKAVVEEMAKSDPAFMSVTYGAAGTRTGFTT
EIARAIKDCGITPLSHLTCLTSTKDKIDSVLDEWKAEGIENILALRGDIPAGFEFPDGQH
FEHAYELVQEIKAKGDFCIGGACYPEIHPESANRVEDIQHLKEKVDCGIDFLTTQMFFDN
EVFFRFKENCLIKGINVPIIAGIMPITNANQIKRSVELSGCKFPGKFEKIIERFGDDPAK
MKQAGIIYATEQIIDLMANGQDHIHIYTMNHPDVAGSIMKGLSAIING
>A0A344LIZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis albispora|TrEMBL
MSTLREELATGRPSFSFEFFPPKTEAGERRFWDSVRRVEALAPTFVSVTYGAGGSSRERT
VKVTEAIVADTTLRAVAHLTAVGHSVAELRQIIGQYAGAGIRDVLVLRGDPPGDPRARWI
AHPQGFTYAAELVSMVKSMGDFSVGVAAYPELHPRSSDVDSDTRHFVAKCRAGADYAVTQ
MFFDVTHYLRLRDRVEAAGCSTPIIPEIMPATDFRQIHRFAELSDASFPPELARALEHAT
PADAYRIGVDHATAMADRLLAEGAPGLHYITLNKSDAALDIHRHILTGPASRAA
>A0A2N6E0J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MSRLSEQLLAGRFVVTAEIAPPKGIDVTETLAVANRLEGMAAINVTDNQGANMRLSASAL
AALLAREQLEPVLQITCRDRNRMALQSDLLGAAAHGIENLLLLSGDHACFGDHPDARPVF
DLDSVQLLQVVETLQRGVDMVGESLAGTPTFFPGAAVAPEAEPFELMFRKFEKKIEAGAR
FFQTQAVFSPEKIERFMDEARRYQTPVLAGVLLLKSARMARFLNEHIPGVRVPEHLVERL
DKAHKPQAEGVAIARDMIAMARERCHGVHLMTLGREDLIPDLLS
>A0A4U5WAR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lasalocidi|TrEMBL
MTTFSFEFFPPRTAKGERTLWDAIRRIEPLAPDFVSVTYGAGGSSRERTVDVTKRLVTET
TLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPAGPWVPHPEGFTHAHE
LVRLVKESGQFTVGVAAFPERHPRSPDWDSDIRHFVAKCKAGADYAITQMFFHVEDYLRL
RDRVAAAGCDTPIIPEIMPATDVRQIARFAQLSGAAFPEALAHRLEAARDRPGEGHRIGV
EYATAMAHRLLAEGAPGLHYITLNRSTATLEIHRAVLDSLTPAPAAPAPHSRVPDPRRAP
HALAAHR
>A0A1F4MQV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFCSPLOWO2_12_FULL_64_99|TrEMBL
MTQSSPNSLPVSVEFFPPKTPEGVDKLAAVRQQLYAIRPEYCSVTYGAGGSTQEGTLQAV
RAILSEGCDAAPHFSCIGASKASVRAELAQFRAEGIQRIVALRGDLPSGYGGFGEFRYAS
DLVAFIREETGDHFHIEVAAYPEMHPQARNPQADLQAYVAKVKAGADVALTQYFFNSDAY
FRFVDEAEALGATIPVVPGIMPITNSSQLLRFSDACGAEVPRWIRTRLEGFGDDKASIQA
FGLDVVTELCEQLRSVGVPGLHFYTMNQAAPVLAICERLGLTPA
>A0A1G0PCV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium GWA2_35_9|TrEMBL
MKVIEHLAKAKEPLISFELIPPKRGGDFISLLSVIEEVSKYNPPFIDITSHPAEVVYEET
SKGIKKIIKRKRPGTLGICALIQNKYNIDAVPHVLTNGFTREETEDFLIELNYLGIENVL
AIRGDDLGYQKPVPEGRSKNIYAADLVKQIVNMNNGKYLEESLLDAKPTNFCIGVSGYPE
KHFEAPNLKTDVKFVKQKVDAGAEYVVTQMFYDNKVFFDFVDLCRKEGINVPIIPGLKIL
TTKAHLVTIPKNFYVNLPQDLVEEVNAAKPEQVLDIGVEWAVKQVNELLDKNIPSVHFYI
MQNSKPVKKLMERLKQFKKIA
>A0A4U5WES0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lasalocidi|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTFSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPQGLTYAAELVELIKASGDFCVGVAAFPAMHPRSADRDVDVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVAAAGCDTPIIPEVMPIASVRTLERVPSLTNAAF
PAALKERILTAKDDPSAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHPPQA
>A0A0C1KLW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. C5pp|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLQLPR
>C3K3G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens (strain SBW25)|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFENDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISTMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A5P2H4I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus pauculus|TrEMBL
MTDRYYSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIDAAPHLSCVGSSRDSIRQILNTYREAGIRHIVALRGDLPSGMGEIGEFRYANELVAF
IREETGNWFHIEVAAYPEYHPQARSPRHDLDNFVRKVKAGADSAITQYFFNADAYFRFVD
DVRAQGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLEGFGDDRESIRAFGLDV
ITALCERLLAAGVPGLHFYTLNTAGATKAIWERLKL
>A0A1E7IN64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium C00003093|TrEMBL
MRVTNLWKKNERPTLSFEFFPPRSEKDAGKFEKVIDALAELNPDFVSVTFGAGGSSREGS
YQLVNKLIKEKGLDVIAYLAGYGLDPDEIISVLDSYQDLGVETILALRGDPPRASEGFTP
HPQGMHHASDLLEFMGERYGFCVGAAGHPEGHPEAESKEKDLEYLKLKVTNGAEFIIANF
VYDTRFFFDFVERCRAIGIKVPIIPGVMPIYSVKLLEILTKTCGATITEEIHRGLAELPT
DDNKAVAEFGIDFATQQCRELIEKGVPGIHIYTMDRAKAATEIVQRLRSEGLL
>A0A1Y2CRM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoclosmatium globosum|TrEMBL
MERMYTLGPEFVDVTWGAGGAQSELTLQICTTAQSVAGLETCMHLTCTNMPREKIDWALK
NAKEAGIQNILALRGDPPHGHSDWQKIDTGFAYAIDLVKYIREQYGDYFCIGVAGYPENH
IENPDPEADFRHFIEKAKLADYVVTQLFYDCDIYLAWVDRVRAAGVTIPILPGIMPIQMY
GGFKRMTTLSKTRVPAFIDAALEPIKDDDKAVKEYGVRLAIDMCNKLRAHGQKGFHFYCM
NLEKSVRLILEGLGFVAPIEVAKPLPWNPSLAKNREKESVRPIFWRNRTRSYVLRTESWD
DYPNGRWGDSRSPAYGDLDGYGVSLKFTPEEALKVWGTPKTHQEIYTLFAEFCKGNLSAL
PWCDNMAPESESIKSPLASVNMKGFLTINSQPAVDGIPSSDPRVGWGPKNGFVYQKAYVE
FFVSPEALQKLIKKLGENPYITYYAVNKQGDLKTNVQAEGPNAVTWGVFPGQEIVQPTVV
DGMSFMAWKDEAFELWNQWARIYAPGSESSKLIQSVSDTWFLMNVVNNNYRDAQAIFEIF
N
>A0A7H4K622|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oricola sp|TrEMBL
MNQPRIPASIEVAPKQAIESADLPGLFPPGTRVYITDVGSDPSPTLVRAARRVRELGYEP
VPHFASRRLTTRTALDERVRATVAEAGVTDILVIGGGLERPAGAFTSTMEVLETGIFDAN
GITDIGIAGHPEGSPDFNEQVALEALRLKKNFGERTGARMRIVTQFGFDGERFARWANGL
RDNGIDMPVHLGVAGPAKVTTLIKFAAMCGVGNSLSFFKRNTRSIATLATSHSPESVVGP
IEQAWHDNPTGAIRQIHVFPFGGIKKAAEWLDQRGSWDIKTSLYPHVQSNGH
>A0A4Y7QX90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. BH2|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7M2V646|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. BDA59-3|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRAIAKDYWDNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVEAGANRA
ITQFFFDVESYLRFRDRCASTGIDVEIIPGILPVTNFKQAKKFADMTNVRIPAWMSQMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A7U3F3E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella africana|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A6P1G5D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Empedobacter brevis|TrEMBL
MKVTQHIERANGKPLFSVEILPPLKGQDVNATFKTLNPLVELNPAFIDVTYHRQEYIYKQ
KENGLLKRYQVRKRPGTVAICAAIQNHYKVDAIPHLICGGFTKEDTEDALIDLNFLGIDN
VLVLRGDPIKSEKLFVPEMGGHAHASDLIGQITGLNTGSYLDDELQESHPMDFCIGVAGY
PEKHFESPNLAMDLHYLKKKVELGADYIVTQMFFDNQKYFDFVNKCREMDIHIPIIPGIK
PLTTFSHLTSIPQNFYIDLPEPLSMEVLKAKDKEAVKQIGLEWSIHQCKELIEFGVPGLH
FYTMSNSNNTKTVAEAIF
>A0A6J4I2X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Acetobacteraceae bacterium|TrEMBL
MDQSFPGTLQRWLTAPRVGALPAPAAMPAPQLSFEFFPPKTEALEAQLWACVRRLAPLRP
RFVSVTYGAGGSTQARTHATVSRILRETTLTPAAHLTCVDASRAEVDRVAREYWDAGVRH
IVALRGDQPPGVERYEPHPDGYAYAADLVEGLRRIAPFEISVAAYPEAHPTALSADHDLD
NLKRKIDAGATRAITQYFFDTDVYLRFLDRCGAAGITVPIVPGIFPVNSIVQVKKFSAMC
GASVPGWMDHLFDGLENDPETRRMVSAVVAAEQVRLLQANGVDEFHFYTLNRPDLVYAIA
HILGARPASAEASAPASANGVVEERAAAGAASTPP
>A0A7C6M9L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MKINDILEKRKLSISFEVFPPKKNAAIDGVIRCTDELSRLNPDFISVTYGAGGGTSANTV
RIASHLQAIGVTPLAHLTCLSSTKTEVHKIVTELKGKNIQNILALRGDRPNDPDFVPPGD
YCWASDLVTDIQSLGDFCVGGACYPEGHPESGGRDHDIENLKIKVDAGCSFLTTQMFFEN
SLLYSFLYRAQARGIRVPVLAGIMPVTSGKQIHRIQELSNAYLPPKFLALVDRFGDNNDA
MKQAGITYASEQIIDLIANGVRGIHIYAMNRPDIVSAIMANISSVLEGARV
>A0A0J8TLW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccidioides immitis RMSCC 3703|TrEMBL
MEKISNKIAALPEDANYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT
ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPPRSDE
YNLDGEDDSNKEFTYAVDLVRYIRKKHSDYFCIGVAAYPEGHSDESHPGVQDPVRDLPYL
VEKTKAGADFIMTQLTYDLEAYKRFESMLRNHESGVFKTIPIIPGLMPIQSYPRLTRITK
LSHVRVPPEMLSRIEACKKDDEAVKKVGVDILSELVEGIKTIPGTGPRGLHFYTLNLEKS
VSFILERCNLIPPSSEASSDTDSDSVFASGNLQNGLGTAAGKPPLISRRRASSLNSQPHN
RVIVDRADISSQSSITHEASAQGAGMPALNPPHRNTALQISEGMGALGREATWDDFPNGR
WGDARSPAFGEIDGYGPSLHVTANVARRLWGYPTTREDINNIFRQHVSGGLHAVPWSEGG
AAEETGGLSPETITIRPYLLSLIEKRGWWTIASQPAVSGVRSDHPIFGWGPPGEGFVFQK
AFVEFFCSKDDYRSHLKPLLQRYGHDEFAWFATNAAGDFESSTSSSIPVPTGPVDAVFDD
MDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWDEWRRIFPRGSPT
EKLLNRVKEDTWLVCVIGQRFGAGGDPGKDAMEEGKILWKVLAGENVSLQS
>A0A1M3BNN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium 70-9|TrEMBL
MDLQQRITSRRGEFLLFALTPPRLSTAPAAAQEIADVTFERLRPLDLDGLILYDIDDEAD
RNPAERPFPFLPTMDPGDYLDRHLEAWPTPVVVYRATAKYTEDELRDWIGCQDPATRMTV
FVGAPSGEKRVETTLRRAQQLRAEIAPDLLLGAVAIPERHTRKGEEHLRLIAKQEAGCSY
FVTQVVYDVNAAKNLVSDYAYECRDRGLDPLPIAFTFSVCGSIKTLEFLRWLGVDVPRWI
ENDLRHADDTLDASLEHAEATALELIPFCRHLGVPFGLNVESVSIRRVEIEASVRLAERL
AGELHRGGPCRR
>B9HG95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Populus trichocarpa|TrEMBL
MKVIDKIREAAGGGGDANGNGGDNSSSNKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNP
SFCDITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQN
VLALRGDPPHGQDKFVQIQGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGSDGF
ATPEDYQKDLAYLKQKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINN
YKGFLRMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYT
LNMEKSALAILMNLGLIEESKITRALPWRPPTNVFRAKEDVRPIFWANRPKSYLSRTIGW
DQYPHGRWGDSHNPSYGALSDYQFMRPRARGKKLFEEWASPLKSVEDIYEKFKVYCLGKL
KSSPWSELEGLQPETKIINEQLGRINLKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQ
KAYLEFFCSKEKLNALVERCKAFPLVTYMAVNRGGSWISNVALTDVNAVTWGVFPAKEII
QPTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEVQNSYFLVSLVDNDYIHGD
IFAVFAEL
>A0A087VUH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium indicum LMG 11587 = DSM 20214|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLMPDFISVTYGTGKQSDRTATARIARTIH
TEYGIPSVAHLTAQYADKEIVDQALDMFDRAGVAAVLPLRGDSVEGRTPAGVFDHASDLV
AYIHAKRPDMTIFGACYPETHPEAASPQADLDNLKIKVDAGASHLISQLFYDNDYFTDFL
GRARGTGIDVPIEAGIMPITNASQVRHMSEVCAASIPPAVNTILDRWGDDRTSLREAGII
YASQQIADLVSQGVDGIHLYSMNQAGVTRRIWHNVRHLFKVRQASSSMLSL
>Q1YZZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium profundum 3TCK|TrEMBL
MGYSHASHLDSLNQNIADINGDINVSFEFFPPSSEKMEETLWHSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLIAAPHLTCIDASRDELRTIARDYWRNGIRDIVALRGD
LPAQGTKPDMYAADLVELLRKEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNMTQAKRFAAANNVKIPGWLEKQYQ
GLDDDLLSRQMLGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAEVEAK
>A0A607IT20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enteritidis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6M4H9P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Usitatibacter palustris|TrEMBL
MQSQRKRPRLFSFEFFPPKTPEGVEKLRATRRQLAQLDPAFFSVTFGAGGSTREGTLATV
LEIRAEGHEAAPHISCVASTRESIREVINEYRTNGIKRIVALRGDLPSGMAVSGEFRYAS
ELVQFIREETGSAFHIEVAAYPEYHPQARKAQADLAAFKAKVDAGASSAITQYFFNADAY
FHFVDQVEALGIDLPIVPGIMPIQNFSQLARFSDACGAEIPRWMRMKLEGFGDDTASIKA
FGLDVVTELCDRLLQQGAPGLHFYTLNQAGPTSTIWQRLGL
>A0A849TC08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionella sp|TrEMBL
INFKRKVSAGANSAITQYFYNADAYFRFVEDSRKLGITAPIVPGIMPIMKFSQLARFSDM
CGAEIPRWMRKTLEGYGDDTESVQAFGLDVVTQLCEKLITGGAPGLHFYTLNQAGASLEI
VKRLGCQ
>A0A2S4IFJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. morsprunorum|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1A9T1B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylovorus sp. MM2|TrEMBL
MEMTAPMISFEFFPPKTAEGLAKLRETRKQLALLNPKFFSVTFGAGGSTRDRTLETVLEI
QSEGHEAAPHISGVSSSGEEIQGLLETYRNKGINRLVVLRGDLPSGEVSAGDFHYANELV
SFIRQTTGDWFHIEVAAYPEFHPEARSPSADLMHFKNKIDAGANTAITQYFYNPDAYFRF
MDQCQSAGINVPIVPGVMPIYNITQLARFSDVCGADIPRWLRLRLQDYGDDLASLRAFGL
DVVTELCQKLLAGGAPGLHFYTLNQAGIISTIASHLNLQGD
>A0A1G9NSB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Daejeonella rubra|TrEMBL
MKITEHIKNAKGKTLFSFELLPPVKGQSIQGIYDAIDPLMEFNPPFIDVTYHREDYIYKQ
HDNGLLEKVSYRKRPGTVAICASIMNRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADSGFIPTPGGHAYATDLLKQVVDMNNGIYLHEDHDTAYKTKFCIGVAGY
PEKHFEAPNLKSDFNFLKQKVEMGAEFIVTQMFFDNSKYVEFVDQCRKNGINVPIIPGLK
PITSSKQMISLPKIFHIDLPEELSEAVAKCKSEKEVREVGIEHMIAQCKELMTIGAPVLH
FYTMSNPGPTKRIAEAIF
>A0A1F8MP35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_51_52|TrEMBL
MVSRFKEALNSGKFVITSEVAPPKGTNLEKMFHHIELLKDKVDAMNVTDHQSSVMRYPSL
GGCLAVKERGGEAIMQMTCRDRNRMALEADLLFAYSRGIENVLCLTGDAVPVGDHKEAKG
VFDLDSLQLLKAIKQLTAGEDLGGNKLEGAVEFCAGAIVTPEAQPIEPQLIKFEKKVEAG
AEFFQTQAIYDLDNFRKFMEYARKLKAKVLAGIVLLSSARMAKYMTENVPGIFVPKNLID
ELSAVPKENMLAKGIEIAGRTIAALKKEALCDGVHIMAIGKEEVVPDILAAAGL
>A0A5R8VGY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. NamB4|TrEMBL
MSPPSLIDTHPNLSDTAPVALSYELFPPRSPAAAETLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIIGELLDTGVRGILALRGDLPKD
GGEPAPGALRYAQDLIELVRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEEHDVEVLL
AKQRSGADFAITQVFFRAEQYADLLTRARRAGVTIPIIPGVMPLTSLRRLKRLGELAGVE
PAPELIERLAAADSDLDRLHIGVNATVDLANAALEAGAPGIHLYTFNEHQSALEVLDKLA
LPRRTHSSSGRNIAARQLAG
>A0A5C8AML7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVIDHLNASKSTLFSFEILPPLKGKSIQSIYDGIDPLMEFKPKYINVTYHREEFIYKER
ENGLLEKIAIRKRPGTVGICAAIMNKYDVDAVPHLICGGFSKEETENALIDLQFLGIDNV
LALRGDSIKTEASFRPHPEGHRYAVELIGQVVDMNNGNYLTEDYQLEPTDFCIGTAGYPE
KHFEAMNLSTDLMHLKNKVDAGASYIVTQMFFDNQKYFSFVRACREIGITVPILPGLKPI
KTLEHASFLPKFFHIDLPEDLSKEILKCKDNKAVAEVGIEWGIQQSKELKDAGVPGIHYY
TMSNCSSVKAIAAEIF
>A0A511AXI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter wancherniae NBRC 103581|TrEMBL
MPAQTRTVAGPEISFEFFPAKTEKGAESLLQTSRTLAGFGPRFMSVTYGAGGSTRDRTLS
TLKDMVRETGVPMAGHLTCVGASKGEVEAVARAYWDAGVKHIVALRGDPPPEANGVYTPH
PQGYVGAVDLIEGLRKIAPFEISVAAYPEAHPAALSPEADLAHLKAKLDAGGDRAITQFF
FEASTFLRFRDRAARIGITKPIVPGILPIGSVAQAWKFADMCGASVPAWMRDLFDGLDER
PQTRALVAATVADRLCQELRAEGVEHFHFYTLNHADTSYALCRLQGRNMQSS
>A0A1I0PWC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] fimetarium|TrEMBL
MKIDSIFKKKKPILSFEIFPPKKEIALLNIDETLKSLSELNPDFISVTFGAGGTTTNNST
VEIAKKIKHEYNIEPLVHLTCINYSKAEICDILEQLNDAEIKNILALRGDINPEFPRKND
FTYASDLVSFIKQYGDFCISGACYPESHIEAKNVSEDILNLKKKTDNGVSHLISQLFFDN
NLFYSFNNKVRVAGVNVPIEAGIMPVINKTQIDKMISLCGASLPTDLRKMIQKHENNCDA
LFDAGIEYAIDQIKDLLEHDVEGIHIFTMNNPIVARKICEGIRPLL
>A0A2E4YTZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVTEHISNSKDTIFSFEILPPLKGKGIEDLYAGIDPLMEFNPPFINVTYHREEYQYKEM
GNGLLKKVSVRKRPGTVGICAAIMNKYKIDAIPHLICGGFSKEETESALIDLKFLGVDNV
LALRGDPIKSEQIFTPAQGGNAYALDLIKQMDEMNQGQYLHEETKNNPSNFCIGTPGYPE
KHFEAMNMSTDLKYLKMKVDAGADFIVTQMFFDNSKYFSFVKKCREIGINIPIIPGIKPI
TTLKHISFLPKFFHVDFPDALSNELSKCKTNDQVKQVGKEWGINQAKELKDNNVPVIHFY
TMGKGESVKNIAKAVF
>A0A2P8WCF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|filamentous cyanobacterium CCT1|TrEMBL
MPKEDFLTSAPLGYRLRTAAKAGQFLVTAEVMPPKGGDPAHMLAMGQLLKGRVHAVNITD
GSRAVMRMSSWAAALLLQQQGVEAVCQVACRDRNRIALQADLMGGYALGLRNILALTGDP
VKAGDHPEARGVFDLESVRLLKLLDKLNCGVDSNDKPLTDGALDLFAGAAIDPQSSSWLG
LQRRFEAKVKAGAQFFQSQMITDFDRLGKFMDQVAAGYNRPVLAGIFLLKSAKNANFINR
NVPGAHIPQAIVDRLAAAADPLQEGVQIAAEQVQAARQVCQGVHLMAVRREDLIPQILEQ
GGVAPVNVAPDVALDAALTQG
>A0A7K0IX84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
MNEKTYTIIDRLQRELLTGDGAVGTMLYAKGVSLDSNFEHLNLIRPALVKELASEYAAAG
AQIIETNTFGANFTKLSAIGLGHKVVEINLAGARIAREAVAGREILVAGSVGPLVSVKGD
DKELSPAEMEAIFSVQCKALTEGGVDLLLLETFSSLVQLEAAVRAARGCSVPVCASLAFL
EGGRAADGTSVERFCEAMEAAGADLIGANCGAGPMELLKVIKRLATLTDKPISAYANSGF
PEYRDGRYIYRATPEYFADMAAEMAAAGANLLGGCCGTTPEHINAIARKITGLKPAVRSR
TPLITVSEPVEAPQKAASFLDNWGSRKVITVELDPPKGIDCSKIITGSRRLKEAGADAIN
LAENPLARPRMGNIALGSIIQREVGIEVIVHVTGRDRNLIGMQSDLMGASLLGIRSILAV
TGDPATMGDHAGAKSVFDLHSFTLIKLLSDMNRGVNAIGNPIGEGTGFTIGAAFNPNTRN
MNVQAERLRKKIANGARFTQTQPIYDPAILFEALDSTGDCDIPFLPGIMPLVSERNAEYL
NNEVPGITVPDAVRARMRGLEKEAGAREGLAIAKEFIDATFAAVGGYYLIPPFGKYELAE
ELIKHIQQREREQQ
>A0A7X8LYK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKTVEFFKKKTVLSYEVFPPKRTSPVNTIYDTLSELKELSPDFISVTYGAGGGENNNQTF
EIASAIKSYGIESVSHLPCIGLTKEDVSAKLKELKRAGIENILALRGDVPSEGCIQGDFR
YASDLIAFIKSQGDFNILAACYPEGHIEAESKLEDIRNLKRKVDAGANHLVTQLFFDNEF
FYSFIERCQLADINVPIEAGIMPVINKKQIERMASLCGVTVPKKFVTMMERYENNPIAMR
DAGIAYAIDQIVDLTAQGVDGIHLYTMNNPYIARKIHEAIHSLI
>G3PGH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gasterosteus aculeatus|TrEMBL
QRGDRSSQSCKSDSSGGESSRESSRSSTPVLDGDRCDRLRDKMRRRTESGDRWFSLEFFP
PRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESIL
HLTCCDQTKGKITGYLAKAKHLGLKNIMALRGDPIGADWEEEEEGFNYATDLVKHIRSEF
EDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTFLKFLDDCRAI
GITCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITRVIEPIKDNDAAIRNYGVQQAVEMC
RVLLDSGKVPGLHFYTLNREVAIMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIF
WASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSPKDALLQMWGDELK
NEESVFEVFTCYITAQTNCNGHKVLCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQP
NINGKPSADPIAGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKNYEPRVNYHIVNVHGR
NLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWAKLYEDESPSR
MIIKYIHDNYFLVNLVDNDFPLESCLWQVIDDMFKMLDAPPEPEDGSVSE
>A0A7X5D0S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKAAGITTVLALRGDPIKKPAAGTPSANASGTDSKSTAGTSASHTGATNAAAGGTTEAAA
HEIGASNDAPGTGTVAGALGNASNSTVGAPEFVHATDLIPLLKDAGFCVGAAAYPEGHID
CLDLQADIEHLKRKQDAGADFFITQLFFDNDDFYRFRERARAAGITRPITCGVMPFLGKS
QIERMVFLCGSSLPSPIIKLLARYEDDPVALRQAGIDYACKQLVDLGRNRVDGVHVYSMN
HPDIALAAAQALAEAGLRD
>A0A819ZD99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood2|TrEMBL
MTLTHTEKNAASNHHDAHENGIGAENMSNSSHHFVDLKRSESEHACLAARGNSLQPVKYV
SLTEKIEKKIANNDRWYSLEFFPPRTTNGAVNLIGCLERMATGDPLFCDITWHTAGDPAG
TKETSTMMIANTMLNYCNIDTMLHITCYGAKKATMIEYLSKAKNFGIRNLLALGGDPPVG
ETWDPEKNDFRYASDLVKFIREHFGDYFVICVAGYPKGHPDSKNYEEDLGYLKEKVDCGA
DFIITQLFFQAETFLKFQSDCRAVGITCPILPGIFPIQNIVRLTKLDVPDAIQTHMESIK
DNDQAIRDFGVQTCVDLCKALLDSGKVHGLHFYTLNREYATTEILKQLGFGFEDPPLRAL
PWKKTSRNHVRSKEDVRPIFWSTRPKSYIHRTSNWNEFPNGRWGISSAPSFGVLTDYHLF
YMKIDAAHNELLDEWGHELTSEQDVWKMFACYIGGEKNSSDKIVRHFPWKDEDMSLETNL
IHNELVEYNRKGILTINSQPAVNGKPSTDPIFGWGEKNGYIYQKAYLEFFTSANNIPALR
AVLKDFPGVNYHFVNKSGEVNETNTDDEQPIALTWGVFPGKEIIQPTVVDPVSFMIWKVT
NLNAFNFNYSYYFFNIKDEAFNLWMERWVDNDYPQGSCLWAVLDAMFEYQQKTNQDTNS
>A0A8H3YFS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naganishia liquefaciens|TrEMBL
MAKLSSLIAREPATAFHTFEFFPPRTPQGLANLLDRIHRLISDPLRPPVGISVTWGAGGS
TAVKSLELAGEIVRLVREDARGADVQVVLHLTCTNMGTRLLDQALAKCRELGIQNILALR
GDPPRKEEYRPAPGPETASLSPTTPADRAPLGDLDPADMIHEDASSGDQDHDEFTYAEDL
VRYIRAGPHGDWFCIGVAGYPTPHVDSPSVESDVAFLAQKVNAGADFVVTQLFYDVDGFL
RWVERVRSAGVDVPIIPGIMPIQNYASFRRLVNLCKCPVPRDIIDDLEPIKSDDAAVKRY
GITLATTMIQRILDARLPQVHGVHFCTLNLEKSVRTIMDNLGWTSATAYRTPAADLTGEH
HHHHRDLLIEQNGTMVPATAADLSASSPSRQVQALSISPSDAAQMAQVGFKHRQMHQLGI
TGAVEDAAGAGPHQVQPGGGVVEDWDEYPNGRFTDVRSPAYGEIDGYGNGLKITPAQALK
DWGAPVDAESLSALFTSYLQSAPSTPTTPFCDLPISPESHTILHYLIHLNSPARQMWTVG
SQPAVDGARSDDPIHGFGPKGGYVFQKSFVEFFVGGVRDVERLQERIEREGQGAIKFYAG
NKRGDFISNLDNEDVNSVTWAVFPGQEIVTSTQIQEESFLAWKEEAFEIWTEWSRLYPLR
SASRKLLQGIADNAWLVSVIHHDYKDPEGLWRFLLGDEYEAVRQKAQKKQ
>A0A5C5XY87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula solitaria|TrEMBL
MKRSPPQQPFELSMTLADQYNSDGCAISFELFPPKTDAGIESLCENVERLLQFQPRFFTC
TYGAGGSSQGTTLEVLQRVKQITKLPVASHLTCVGLNTEQLSDYLRRATEIGVDYIVALR
GDPPKGTTEFSVTEGGLRYANELVGLIREQFQDLGIAVAGYPEVHQEASDAQTDLDNLKR
KVDAGADIVITQLFYDNADFYRFRDDCVRAGITVPIVPGILPVTNFKQAQRIAGMCKAAI
PISLADAMTTDDSPEHQFRVGVDHARQQTIDLIEHGVPGIHYYVLNRSAAAAELLDGLQL
AGQA
>A0A8C9MHV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serinus canaria|TrEMBL
MLGLSIGFFIHLLLTPAVPAPCRDPRTDHPRSAPLCRAPTMVNETQHSCSASSSSRSDGG
SSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDKWFSLEFFPPRTANAAVNLIS
RFDHMGAGGPLFVDVTWHPAGDPGSDKETSSMIIAYTAVNYCGLETILHMTCCNQTKDDI
TGHLQKAKRLGLKNIMALRGDPSGEEWEEEVHGFNYAVDLVKHIRNEFDDYFDICVAGYP
KGHPEAESYEADLRHLKEKVYAGADFIITQLFFRPETFLKFMKDCQAIGITCPIIPGIFP
IQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGL
HFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRT
QEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFTCY
ITGEPNRNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNINGKPSTDPIV
GWGPSGGYVFQKAYLEFFTSSEIVRALLKVLKKYELRVNYHIVNVKGENITNAPDLQPNA
VTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYL
VNLVDNDFPLENCLWQVVEDTFELLNAPIQQ
>A0A7V6UXB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKIIDLFENKKTVISFEIFPPKQDAPLDKIYNLLEHFKLLNPDYISVTYGAGGNTRGRTI
EIAEKLKYKYNIESMVHLTCVNHTEQQIENLLVLIKEKGLKNILALRGDPPKNQPGYDFT
KNYYKHAYELIQHIKQRYSFCIAAAAYVEGHVESRRLSDDLAHLKNKVDAGVDFLITQFF
FDNRIFYDFLDKLASVNINCPVAAGIMPVFNADRIKEIAAKSGCSIPAKLVLLMDKYRLS
PDDMLKAGIEYAAVQIRDLIDNRVDGIHIYTMNRYDSTRDILEQAGILQVYA
>A0A3G8WKG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium taklimakanense|TrEMBL
MKITDHIKKASGKTLFSLEVIPPTKGTGIEDLYKNIDPLMEFKPPFIDVTTSREEYVYIE
KGNGLMERKITRMRPGTLGICASIQHKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
VMALRGDAMKGQNQFLPTEGGHHHAIDLVHHINDIGRGKYLTDEKRCKEENKFCIGVAGY
PEKHIEAPSMNYDLQKLKEKVDAGADYVVTQMFFDNQKYFNFVKEAREIGIEIPIIPGIK
PIATKGHLSMLPKTFKIDLPEELIAEITKAKDNTAVKQIGIEWAVKQCRELLNFGVPVLH
FYSMGKSDNIRKVASQLF
>A0A2N2HIK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-19|TrEMBL
MKEMSRLKAVLEKGGFAVTAECGPPKGADPDTVLRKGQLLNGKVDAVNVTDNQTAIVRMS
SLAACTLLKSAGMDPVLQVVVRDRNRIALQSDILGASALGIRNVLCLSGDHQSFGNQPQA
MGVFDLDSIQFVQTVRSMRDQGLVLGGDKLSRGPDVFIGAAANPFADPMAFRAVRLAKKI
AAGAEFIQTQCIYNLERFETWMGLVRDRGLHEKAFILGGVTPLKSAKMAKYMRDKVSGMD
IPDQVIERMEKVPPGKQREEGIRICVETVERLKEMPGVKGVHIMAIEWEDAVGEIVEKAG
LLPRPS
>A0A2D7F2P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceicoccaceae bacterium|TrEMBL
MESQTIIHTIASGKKTLSLEFFPPKSDKAIQQLKESSRDLAKLSPDFVSITYGAGGSTRK
STFTYAEQLKTDHDYKVMPHLTCVGHSQNELAEIIQQYQEAGFRTLMALRGDPQGDSQTF
TPHPDGFQFANQLVAFIKSQFPNFEIGVGGYPEKHPESPSQTNDIQNLKKKVDAGADFIT
TQLFYNNDHYYRFVDQCRDAQIDCPIIPGLMIPTNLERVERFCHFCQAELPDSLKAALSS
AHEDSQALQDVAVEWTFQQVKALLENGAPGIHLYIMNQSKFVLALYQKLREADHLFHT
>A0A368B7N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceicoccaceae bacterium|TrEMBL
MTAVSLKTRLQSGKALFSIEFFPPKSDTSAEQLLRTAEALKVYSPDFASITYGAGGSTRS
RTLKYARHLSEDCGYAVMPHLTCVGHSREELRGIIAEFREAGLGQIMALRGDPPEGETDF
KPHPEGLHHANELVGLIHETFPECTIGVAGYPEMHPEASSPDIDLLNLKRKVDAGGHFVT
TQLFFDNTKYFEFVNRTSQAKIEVPVLPGLMCVTSREQILRFCAMCRASIPAELNQRLLA
AGDDAAAVEAVGIDWVYHQARELLERGAPGIHLYILNREGPAVKIMEKLKAAGFYKA
>A0A1F3H0F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWD2_45_23|TrEMBL
MKISDFFNQEGKTAFSFELLPPLKGNSIQQIFNTIDRLKEFDPKYINITTHHSENEYKED
EQGVYRKVNVRKRPGSVAIAAAIQNRYGIKAIPHIISQGFSKEETEYALIDLSFLGVTDL
LLLRGDTKKLDGEQRKMDSHLHATGLQEQVNNFNKGIAYDGSTFTPPDTPFAYGMACYPE
KHEESPNMESELLYTKMKVDEGADYLVTQMFFDNSKYFAFVDRCRAAGITVPIIPGIKPI
HLKNQLTVLPKVFRSDIPADLEKELRRCKDDAEAREVGVAWCVAQCRELMQHNVPGIHFY
ALMATESVHKVASEIY
>R5BZS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. CAG:933|TrEMBL
MVTSLREKHKAGQFTITVELDPPKSASANKTFKEAAQLLDKVDAINIADCPMAKLRMSPI
ALAHLIKYRAQIDTIFHLTCRDRNILGLQAELLGAAALGVNNILTLTGDEPSRGDHPDAK
PIFEVDSMGLLKIAHTLNSGFDLAGNELEVPTNFYIGTTGNPGADDLEEEKAKIIRKVEA
GANFIQTQPIYDLEKAKRFIDMVAPLGIPVMLGLIPLKSFKMATYLHTKVPGISLTEDIL
DRMEKGGKEAGLEIALETLLAIKKVAQGVHIMPLNDIQTVLYLIDHV
>A0A3B9H2F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas adhaerens|TrEMBL
MSTSTPHVSFEFFPPKSDAMANRLWDTVQRLEPMAPDFVSVTYGAGGSTRERTHETVKRI
AQETSLKPAGHLTCVSATKEEVLAVAEEYWQAGVKHIVALRGDPPAGMGAAFDVYPGGFR
DAVDLVKGLREHRPELGKCFEISVSCYPELHPESRGWDAEIAYLKAKQDAGADRAITQFF
FEPETYLRFLDKARAGGVTMPIVPGIMLQANFRGLQRISGLCGATIPDWLADLYDGLDDD
VETRELVTANVAADLCRKLAEEGVENFHFYTLNRAGLALSTCRLLGLKPHPAKAA
>A0A197BU56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. 20006FA|TrEMBL
MTLSFPSVEEARRALDAPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIQTLTPLAPKFV
SVTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKAEIDGVADAYWEAGVRHIVA
LRGDPPEAGAKFEAHPDGYKGAAELVEGLVKRHPFEISVAAYPETHPDALSARGDIDNLK
RKLDAGATRAITQFFFEPDTFFRFRDTVAAAGIDADIIPGIMPVSNFAAVQRMSAMCNTD
VPGWMGKLFEGLDDLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPATLEKTA
>A0A412W732|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odoribacter splanchnicus|TrEMBL
MTKVIDIINQKKAPFASFELVPPLKGSDINKLYGAIEPLMEFAPPFINITFHRDEVEFRQ
TADGTFEKVTITKRPGSVAIAAAIMKRFPVEVVPHLICGGASKHQIENDLIDLNFLDIQN
VVALRGDAIPGQKYFVPEPDGHRYSCELVEQIHNMNRGIYLDECLKNAVPTNFCIGVAAY
PEKHYEAPNIDIDIENLKRKVDAGADYIVTQMFFDNTRFYEFAAKCRAAGITVPIIPGLK
PISTQTHIEMLPRAFSIDLPQELMNEVRKCKDNKAIYQVGIEWCTAQSKDLLVHGAPAIH
YYTMGKADNIREILKRTF
>A0A4Q4GWW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter piscicola|TrEMBL
MSRLSHYLAQNQFCVLLEYLTSTQEILPVPQQLAGFPVCMTLADRVHSDTDLSPLDAANL
YTKDIEKVLHFAGKGRDISDFENFLTAAKNSGQHNLLLLTGDKLKHHNFGEGQQPRTRYL
ESVNAVMAAKKQGGFLIGVAFNPFKYAEAEQDAQYFKLRKKLTAGADFIITQLGYDIAAL
QQVKSFLIEQHDAQKILACVMPLTLARAHFMVKHQVAGIVITPHMLKVLQEEKTLGLTEP
VYQRCALQILLCQHLGFAGVHLSACHQAEEQLRLQRYIETYRTLGFDACLSLWNDLWQVQ
TGKEFHPELRSYSSPISSAQILKYQHLSFIHDAFFESKMAKGVGRFIFKSHFWDQTPMAH
ALLKTEWVSKHAIVGCESCGQCRLGETLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKTELIPTVPLHIRDSSSWKNWFRDI
>A0A0C2W3U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jeotgalibacillus alimentarius|TrEMBL
MRVLCLSELNEHLPLFIYTRIRKGERMNLLDEMKQRILIGDGAMGTLLYSYGSDQCFEEL
NLSQAAHIQQIHQAYIDAGADVIQTNTYGANYHKLERYGLEEKVKEINTAAVKNAKAAAA
EDTFILGTIGGIRSFRPQSIEINEIKRTFREQLYCLLLEGVDGLLFETYYDFEELATVVE
ISRNETDIPIIAHISVQEPDVMQNGKPVAEALLELESLGADVVGLNCRQGPFHMIKSLEQ
VPLPEKAYLSCYPNASLPSYSEGSLQYSNNATYFGEVAPAFREQGIRLLGGCCGTTPDHV
RAFSQALKGLTPVTEKKVEKAEKIILHAREKDLPEPLPEIVDRRKSVIVELDPPKKLQTD
KFIEGAKALGAAGADAVTLADNSLASPRVSNESLGYLIKEQGVRPLVHLTCRDRNLIGLQ
SHLMGLHTLGLHDILAVTGDPTKVGDFPGAASVYDVSSFELIEMIQQLNNGMSMSGKDLG
EKASFTIGAAFNPNVRSVERAVQRLEKKITAGADYFMSQPVFSEEKLIETAEAVKDLGKP
VYIGLMPLTSSKNADFLHNEVPGIKLTEQVRDRMAAVSGDREKSYLEGLAITKSLIDTAL
DLFNGIYLITPFMRYEMTAELTRYANEQAAKRGGQERAIY
>A0A834UPN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmota monax|TrEMBL
MWASEAGSMRWSVPPSISRRRAMETRGLGGPTPPSEGSSSGSESSRDGSRCSTPGLDPER
HERLREKMRRRMESGDKWFSLEFFPPRTAEGAANLIARFDQMAAGGPLFIDVTWHPAGDP
GSDKETSSMMIASTAVNYCGLETILHMTCCRQRREEITGHLHKAKQLGLKNILALRGDPI
GDQWETEEGGFSYAADLVKHIRSEFGDYFDICVAGYPKGHPDAESFEDDLKHLKEKFSAG
ADFIITQLFFEADTFFHFVKACAATGITCPILPGIFPIQGYSSLRQLMKLSKLEVPQEIK
DVIEPIKDNDAAIRNYGIELAVSLCRELLASGLVPGLHFYTLNREVATTEVLKRLGLWTE
DPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELR
DYYLFYLKSKSPREELLKMWGEELCSEESVFEVFAHYLSGEPNRHGHKVTCLPWNDEPLA
AETSLMREELLRVNQRGVLTINSQPNINGRPSSDPVVGWGPSGGYVFQKAYLEFFTSRET
VEALLQVLKKYELRVHYHIVDVKGENVTNAPELRPNAVTWGIFPGREIIQPTVVDPVSFM
FWKDEAFALWIKRWGKLYDEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFE
LLNRPAQSERESEAL
>A0A828YUN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. malvacearum str. GSPB2388|TrEMBL
MIPTDTPSGASTITDAYSLEVSVKDIGALTNAAPRMPPGSDMFIPYLPGQTEAARLAAAQ
RVRRLGFEPVPHLSARRIGSLEELQAAIARLVGEADVTRCLVIAGDPSTPKGPFADSVSL
IETGVFERSGIRTIGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
IVMTWLEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLASRLTEAHGDVRLHLFPFGGIAQSVEWVAHYRSCEVSQDRVSSVAAD
>A0A839LDT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mitsuaria sp. WAJ17|TrEMBL
MTLQLAPTRSAAQRLIERGAVLRASGAKVRKAGEDVGEHEVLAVTDDAELRYVSRGGLKL
EGALQASGIAVQGLTVLDMGQSTGGFTDCLLKHGAARIVGVDVGHGQLHAALQADVRVTA
LEGLHVRELAGSALPAHAPPGGFPLIVGDLSFISMIGAFAQLDPWLAPEGQVLLLIKPQF
ELGPKALSRGGLVKDPALFPQLEQQVRTTAQGLGWHVQGYFSSAITGGDGNTEFFLWARK
TSGPPRSHRKGIAMSQANIPAARPPVSFEFFPPNTPVGTEKLRTVVQELSAVRPHYFSVT
YGAGGSTREKTLATVSEIAAAGHEAAPHLSCVGSTRENIAEILATYRAQDIRRVVALRGD
LPSGTATAGEFRYAAELVQFIRETQGADWQIEVAAYPEYHPQQRYAARDLQHFADKMKAG
ASGAITQFFFNPDAYFHFVDEARKLGVTAPIVPGIMPFHNYGRIAQFAARDGIEIPRWVA
LKMEGFMDDTASIRAFGLDVVTRVCERLIAGGAPGIHFYTLNQSALVLELCKRLGLGA
>A0A4R8ENX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. S87F.05.LMB.W.Kidney.N|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFTPKAGGNHYAIDLVRQINDLNCGKYLHEVMDVDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A380QDU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pseudotuberculosis|TrEMBL
MERKLSFEMNSAKNEKEMENIFKLIEFTDTLDPIYYTVNTEIGSSVWSDTYRTVIELREK
TDVPLVPHITINNKKEREIMQIIEQYIKAGICEFFVIRGDKHVYDQNNPINYGVELIELI
RRSDKNIGIKTSLYPDFHKETTDVKEEMDWNERKYQLGVNEFISQLTLNTNALDFLSHWV
DKERPFTPSIMPLGNFSFIEKFTSSNSIDYPLWIKKFANSKSNSNEDKENIGIEIIRFLC
REYLNKRERLHVFTLNKVDVMKRIFQ
>A0A4P6KX06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia lutea|TrEMBL
MADHNFSIEFFPPKTAEGTEKLRATRAKLAELHPKYFSVTFGAGGTTQRGTLETVLDIMG
AGEEAAPHLSCVGGTRESIRAILDEYKSHGIKRVVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQAKSPQSDMDAFVRKVNAGADAAITQYFYNADAYFQFVD
AAQKAGVNVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQVAPTTALWQRLVK
>A0A3G6RYB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium lactis|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIEN
VMALRGDAMKGHQYFEPTQGGHPSAMDLVNQINNLGRGKYLHNEEQACDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKEKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKRHLKLLPQVFKIDLPEDLINEVENAKNNEAVKQIGVEWSIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A4Y9NCI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. AZ43|TrEMBL
MVFGPCGGVRDDERCEVAEHRCVFLDGPLPRWPGPDAAPAGRSGLLARAAAGPVVLADLS
APAFDPATVRRVAGALGDAVDAVLLGEHADRPDLPPTMLAAEVLAAGGRLWTTLACRDRN
RVVLEQELAGLAALGVDGVLCVTGDARGPDVRAGATQVFDLDGLRLAALAAGMGLPVAVP
ESPETPPVALRPVRVAEKQRAGAQLCVLNHVSSPARVAAFVAAARAAGATLPFLAGVAVY
TDEQSARVLQRFPGLRLDDATVERVLSAPDPRAAGIEAAVAEARELLAIPGVVGVNLSGS
GSGQGWDDGARVKAAVAERLRGMS
>A0A5A8UKB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thioglobus sp|TrEMBL
MKVSFEFFPPRSENSKQTLAQARQQLSLIQPEYFSVTFGAGGTTQEETLKTVLDIQANDP
VSAVPHLSCIGSEKSAIITLLDKYKAANIKRIVAIRGDVPSGMSDIGDFHYANELVEFIK
NQYGDHFHIEVAAYPEVHPQAKNAQTDLQHFANKVKAGADSAITQYFYNADGYFRFVDEA
QKLGVDVNITPGIMPITNHTQLLKFSNMCGAEIPKWILERLKLYKNDTESLQKFGVEVVA
>A0A2C5XI40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps australis|TrEMBL
MEKITDKVAALPAGSEYFSLEFFPPKTAMGFANLRHRLQRMEQALRPLFVTVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRRCLDKALDDAKAVGIRNLLALRGDPPRQDE
YHDASDSEDDVDFAWAADLVRYIRKNHGDYFCIGVAAYPEGHGEGSCPADQSLHKDLSYL
VDKVRAGADFILTQLFFDVDAYDSFEKLLRDHSSGVFKTLPMIPGLMPIQSYQMIKRTAR
LSHARIPDAMLERLEAVKSDDEQVKMVGVDIISEMVERLRAVKNRTSNRNGYHFFTLNLE
KAVSFIVERTGLIPDSFEQEEAVIDESSRLALPVVQINGNNSSRGRSHSRSSRRLSSVGS
DPHNRVIVGNRPLTHPEWEATGLEAGVPADSINTRANTLAISEGEGVLGREATWDDFPNG
RFGDARSPAYGEIDGYGVSLRMSPRETLRFFGVPRTRSDIDALFVKYVRGELHQLPWSEE
KLMPESSKIRNQLEELNSRSLWTMASQPAVNGAPSSDATFGWGPHHGFVFQKAFVEFFMS
STAWHQLLARLRSPEVLASVSFYATNSKGDFVSSDSSGGINSISLQASTNAVTWGVYPGK
EIVTPTIIEEVSFRAWSEEAFAIWGEWAKVYGRGSESEKLLKSLQDDCWLVNIIHHDFVD
GDALWKLLSEQRLD
>A0A3S2LLA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.08.1.1|TrEMBL
MNDMRQELIQTRGSATFAFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLATAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLEICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWLRVNER
>A0A3G8GSF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pigmentiphaga sp. H8|TrEMBL
MSSSLSPDPAPADAAPVFSLEFFPPRDIAAQERLVRTAKQLQGLHPHFASVTFGAGGSTR
DGTMLAVSMLQKLGYEAAPHLSCIGSTPESLRDILYTYRQAGIRRLVALRGDMPSGMGDM
GELRYARDLVEFIRQETGDWFHIEVAAYPEMHPQAQGPEADLDRFVEKMRAGADSAITQY
FFNADAYFDFVDRATAKGVLAPIVPGIMPITNYTQLARFSDMCGAEIPRWIRLRLASYGD
DRASIRAFGHDVVVELCQTLLDGGAPGLHFYTMNQADATQAVWKELER
>F6DHG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus thermophilus (strain SG0.5JP17-16)|TrEMBL
MKIRDLLKARRGPLFSFEFFPPKDPEGEEALFRTLEGLKAFRPAFVSITYGAMGSTRERS
VAWAQRIQSLGLNPLAHLTVAGQSRKEVAEVLHRFVESGVENLLALRGDPPRGERVFRPH
PEGFRYAAELVALIRERYGDRVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIEIPILPGIMPVTSYRQLRRFTEVCGASIPGPLLAKLERHQ
DDPKAVLEIGVEHAVRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGLRSASGQP
>A0A2K4WKR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae group genomosp. 3|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLDTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A246JD40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseateles aquatilis|TrEMBL
MTTPVSIEFFPPNTPVGTEKLKTVVQDLRAVDPQYFSVTYGAGGSTREKTLATVADIASQ
GFDAAPHLSCVGSTRENIAEILATYRAQNIRRVVALRGDLPSGTATAGEFRYAAELVRFI
RETQGEDWDIEVAAYPEYHPQQRYAARDLQFFADKIRAGASGAITQFFYNPDAYFHFVDA
TKAMGVEVPIVPGIMPINNFSRIAQFAQRDGIEIPRWVAMKMEGYLDDAASVRAFGLDVV
AQLCERLIAGGVPGLHFYTLNQSALTLELCERLGLARKA
>A0A3D8TDE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIRSKRPYLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A672HBT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salarias fasciatus|TrEMBL
MSAVLNCSYAALENSKESSRCSTPVLDADRSDRLRDKMRRRIESGDCWFSLEFFPPRTAS
GAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCC
NQTREVITGHLAKAKHLGLKNIMALRGDPMGTDWEEEEEGFNYAVDLVKHIRAEFDSYFD
ICVAGYPTGHPEAESYEEDLLHLKEKVEAGADFVISQLFFRADTFLKFLDDCRRIGISCP
ILPGIFPIQGYQSLRQLVKLSKLEIPEEITEVIEPIKDNDAAIRNYGIHQAVEMCRVLLD
SGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRP
KSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLQMWGEELMNEESV
FEVFTSYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELDKVNRRGVLTINSQPNINGK
PSTDPIVGWGPPGGYVFQKAYLEFFTSSENVSALLKVLKKYEPRVNYHIVNVHGLNLTNA
PELQPNAVTWGIFPGREIVQPTVVDPVSFVSWKDEAFALWIEQWAKLYEDESPSRMIIKY
IHDNYFLVNLVDNDFPLENCLWQVIDDMFEPQLHRKDAFTHH
>A0A6M9DCJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 14181154|TrEMBL
MSLLKTALREHHFVCVMEFVPKASAERFAAMQAIMDRAQLCGWPMTVAIGDRVGSPLDMS
PLDALASFDRPVPALPHFSGKDRERHHLLAQLQRMAAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVPALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQAAPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMREMLEAEMAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGIHDLKQLLALEARLAYWQTQVHTLEQWAPA
WQASWQMPGLPAVTFHPPQANWRQGESRVDASFKEKARYHLMHGMHGLLFSRRNSLSKAF
GWAVRQPLWTTRLGAQVLHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVGQTAVLSERLIPCIEVQTRHRSSWPQWFAPPSP
RRVSPQPAPRTQPES
>A0A3M1BND4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ardenticatenia bacterium|TrEMBL
MTHPLLMRLAQGPLLTDGAMGTQLYSRGYSFKQGFDSANIERPQVVRDIHEAYLLAGADV
LETNTFGANRIKLAEHGLQDRVAEINRAAVQIAQAAREALRQPAFILGAVGPLGRMLAPL
GALSPQEARAIFREQIQALIEAGVDGIILETFSSLAEIQEALRAAKEIAPDIPVIAQMTF
GRDGVTKLGHAPVDVAAALLANGADVVGANCGIGPRSVLAAIRTMQAQYPHATYSAIPNA
GWPEQMDGRILYPATPEYFANFAREAAEMGVRLIGGCCGTTPDHIRAMRAALDSWQAGEP
IPARPREPVAVHVRHIAENPAPTALARAFASGHFVTTVELEPPRGVDLTDLLNTAAMLKG
AGATVLNVADSPLARMRMSPWAVASLIQSRVGIETVLHFPTRGRNLLRVQGDLLAAHALG
VRNIFVVMGDPTAIGDYPDATDSYDIVPTGLMKLIKEGFNQGRDFGGNDLGAPTHFLVGC
ALNFGAANLEREVKLLRKKIASGADFCLTMPFYDPDVPRRFIEAYGGPVEIPVLMGVLPL
YNERHAAFLHNEVPGITIPEHVLERMATAENKPQEGVRIALELIDAVRDLVDGIYIMPPF
RKYDIAAQIIRAVYRGSHANLIQEE
>A0A7N8XUU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mastacembelus armatus|TrEMBL
AALLHRIPGGRRSGHISHVAAALQSSMEDGQNTGDRRKPAGTGESSRCSTPVLDADRADR
LRDKMRRRMDSGDRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPSGDPGSD
KETSSMMIASTAVNYCGLESILHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPMGTD
WEEEEGGFNYAVDLVKHIRSEFDDYFDICVAGYPTGHPEAQSYEQDLRHLKEKVDAGADF
IITQLFFRADTFLKFLDDCRANGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVI
EPIKDNDAAIRNYGIHQAVEICRVLLDSGKVPGLHFYTLNREVATIEVLRQLGLWKEDPR
RPLPWAISAHPKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYY
LFYLKSKSSKDALLQMWGKELMNEDSVYEVFTCYITGQPNRNGHKVMCLPWNDDPLAPET
NLLKDELEKVNRRGVLTINSQPNINGKPSADPIVGWGPAGGYVFQKAYLEFFTSSENVNA
LLKVLKKYEPRVNYHIVNVHGRNLTNAPDLQPNAVTWGIFPGREIVQPTVVDPVSFMYWK
DEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLQSCLWQVIDDMFELLD
APTEPLRDITV
>A0A2T6NNB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium symbiont of Ctena orbiculata|TrEMBL
MQRDNQQKTFSFELFPPKTERGQENLQKAVGELRAKQPAFFSVTYGAGGSTRQRTFDTVE
WLIEEQITTAPHLSCIGASRDEILEILAHYKAIGIRRLVALRGDLPSGTGMGELSDLGHA
NQLVELIQERYPQQFHIEVAAYPEFHPQASSAQQDLNYFKLKVAAGADSAITQYFYNADA
YFRFLDSCQQLQIDIPIVPGIMPITNFTQLARFSDACGAEIPRWLRKRLEGFGEDLEAIR
SYGAEIVIRLCERLLEGGAPGLHFYTMNQAKPTLDIWHALSL
>A0A1Q6LQ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:12237_41|TrEMBL
MNFKDYIKTHNILADGSFGTYYAEKYHTNEAPEYANIYHKDRVTNIHSSYLDAGANLIRT
NTFATNTMSMQKDFSFVEDNIKEAVSLAKIAVKLSGKKDIFIAGDIGPVSTVSGVSDENL
INEYFNIAKTFADEGIEIIQFETFMSLDVLADVIPKIKKELGLFIMVSFSVNQLGYSASG
LSAKNLINDICAVDGVDAVGLNCGIGPYHMYNILEKIKLPKDKVLIAIPNAGYPVLTRNR
MEFNSHPEYFAEKTKELLSLGADIIGGCCGTSPEFIKSLYDIMSMDIKADKKIRKADSAD
EKVSKKCGFLYDENGRKKDKKFIAVELIPPFNTDDEKLLESAHYLKNAGVDVLTFPDSPS
GRTRVDSVLMAAKVYRETGIEVMPHVCCRDKNAFAMRAMFMGAKINDIKNFLIITGDPVP
ASARDLVKSVFNFSSVGLMKIAQEMNREVFNENPLNYGGAINQNLINLESIINTTKRKMD
AGASFFLTQPVFSKEEADRLREIKEETGACIFAGIMPLISRRNALFMKNEIAGINVTDEI
VNRYPENGSKEDGEKVAVELAKEIISYIDDFADGYYFSFPFNRVYLLNRILG
>A0A2R6JRB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QS_8_69_26|TrEMBL
MSVKPGSTTTDEGVTALLTDPRFELMPFDSFGEQMGHLPDGASIAITTSPTLGLDATLEW
TEKAAAEGYEIVPHIAARYVRDEDHVEEIAGRLTEAGVTDVFVPGGERDEPAGEFDSAYA
LLSTMEELGYEFEEVGITGYPEGHAFLDEETLAEAMAKKEPYATYIVTQICYDPDEVIDW
TGAIRDRGVELPVEVGIPGVLKYQRLLSISQRVGVGDSVNFLRKTTGIIDFVRQLVGSRG
KYTPDALVDGLAPYAHDPEIGFRGVHLYTFNQVPDTEEWRKGRLGE
>A0A6M9DFM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 14181154|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVQVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMACGELRYASDL
VEFIRVETGDHFHLEVAAYPEMHPQARNFEADLGNFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLALWNNLKLPR
>A0A0E0UEN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium meliloti (strain BL225C)|TrEMBL
MNGRTPYPVDCDGLRFSFEYFPPKNDEMETQLFQTVTALSVFAPAFVTVTYGAGGSTKAR
SLTTVKRMIGEMEIANTAAHLTCVGAPKAEVDAVIDEFLACGVRHFVALRGDPQGGIGSV
YEPFPGGYENAAALVKALRARGDFEISVSAYPEKHPESPDVAADIDMLKRKVDNGATRAL
TQFFFDNDDFERYLERVRRAGIAIPIVPGILPINNLTQVQKFAGLCGARVPESIVSRLGP
IDDQPEERFREAAHIAAEQVADLVRRGVSDFHLYTMNRPQLITAVCELMGYDPEIAPAQP
ADTERSVRAVARA
>A0A812A4V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MRVKDILNATKISFSFEFFPPKTDTGWKQLFDTISELMLLKPSYVNVTYGAGGSTRDRTY
NLVTQIQRETGLTVVSHLSCIGSTKEEIRSILEKYNQSGVENILALRGDPPKGQKLSSLK
GDFKYAADLVAFIKKHFPHMSIGVGGYPEGHPETPNRLKEIEYLKAKVDAGADYIVTQLF
FDNRDFYDFCERCELVGIHVPIIAGILPITSYQGMIRMAELAAGSRLPAPLLKSVMRAES
DEYVEKIGIHWATEQVRDLVDHNVRGIHFYTLNNSRPIFKIYEFLGVRDSIQLSAQPGHV
IRRDTKVE
>A0A081XUK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces toyocaensis|TrEMBL
MRDMLAAGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRAGTVRA
TEQIAADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMADWVPHP
RGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFF
QPESYLRLRDRVHAAGCETPVIPEVMPVTSVKMLERLPKLSNASFPDALKERILTAKDDP
AAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>A0A416NSE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium AF22-6AC|TrEMBL
MKIRDILNKDTATISFEVFPPKKSTDFGNVEAAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGEIQKQHNVPTVAHLTCVCADRGSIGAALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKENGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITEPIIPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGNNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNISEILKA
>A0A1V3K290|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter sp. Ppn85|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMENMLWESIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDATTEELKKIAQDYWDNGIRRIVALRGDEP
KGYDKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHIIT
QFFFDIDSYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPSWLTKAYDGL
DEDPTTRNLVAASVAMDMVKILSTEGVSDFHFYTLNRSELTYAICHMLGVRSSV
>A0A2N2JVJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-15|TrEMBL
MASPFKKALQSGKFVVTSEVAPPKGANLDRMKHHVELLRDKVDAMNITDHQSSIMRYPSL
GGALLVREMGGEPILQMTCRDRNRLALQADLLFASSRGINNVLCLTGDSVILGDHKEAKE
VFDLESCQLLSTVRLMERGKDLGGNALESPVSFCAGAIVTPEADPIEPQLIKFEKKVEAG
AEFIQTQAVYDLDNFKTFMEYAGKFPVKILAGIILLTSAPMARFMNKNVAGIHVPQELID
EMASAPKGRALQKGIDIAGRMIRRIREDKMCDGVHIMAIGKEEVVPEIMSAAGLL
>A0A430DIQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. ABOLF|TrEMBL
MTISVNQLEEARRALDAPLFADMAGDAAVSFEFFPPKSAKMEETLWEAVRTLEPLGPRFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEASRDEIDQVAEEYWAAGVRHIVA
LRGDPPVAGQKFQAHAQGYANAAELVAGLKKLHPFEISVAAYPECHPDSGTKVEDLDNLK
RKLDAGATRAITQFFFTPEAFFRFRDAATAAGISAEIVPGILPVSNVAQTRKFAGMCGAA
IPDWMDRLFEGLDDHPASRQLVAATIAAEMCRRLYAGDVRHFHFYTLNRAELSYAICHLL
GLRPNKAAGAVAA
>A0A2M8DVS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium CG_4_9_14_0_8_um_filter_55_61|TrEMBL
MNQSPISFEFFPPQTAEGVEKLTVVRARLATLKPEFFSVTFGAGGSTQERTVDTIRQIHA
EGYQAAPHLSCVGSTRDNIRAMLLAYRQMGIRRIVALRGDLPSGMAGIGEFQYANELVSF
IRAETGEHFHIEVAAYPEFHPQAQSAQADLLNFKRKVEAGADAAITQYFYNADAYFNFVE
AASKLGVTVPIVPGIMPIMRFSQLARFSDACGAEIPRWMRKTMEGYNDDTEAVQAFGLDV
ITALCEKL
>A0A514EEW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas translucens pv. cerealis|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQASDALSDLRHFKTKVEAGADGAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQALGDDADAIREFGADLV
AALCERLLAGGAPALHFYTLNLAKPTTSVLSRLA
>R6BIW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:56|TrEMBL
MKLSEKMKEKQLLSFELFPPKTEKGMANLPGTIEHLMEFKPEYISCTYGAGGGNVGANRE
VCQMIKKAGSIPVTHFTVIKNTKEGIREQLDQYLEEGVDHMLALRGDFPMGETSTMGDFN
YATDLVKFVRDQYGDKFEIAVAGSPEGHISCRSLEADIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGVTMPVDVGVMPILDQAATINMALSRNGCVMDRELSRLISRHWLFPN
PFAAKDAEGKPFDLFYDKKIAEFKEEGIEYTIRQIDTYRALGVEGIHLYALNKWKDVSEI
INRSGLRTLV
>B6GAW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella stercoris DSM 13279|TrEMBL
MRIDELFARAASQGTTPVSFEMFPPKGELTLERAREVGSRFAELSPGFVSVTYSAGGSTN
NAATTQIASMLTRELGITSCAHQTCISLHREDLPAKIAELRAAGIENVLALRGDVPADAP
TGPGCADYRYAMDIIPALVEAGFCVGAAAYPEGHIECDDLDRSIAHLKLKQDCGASFLVT
QLFFDNELFYRFRERAERAGITAPITAGIMPFMGKQQISRMVFMCGASLPSPVIKLLARY
EDDAESLRAAGIEYACRQLEDLAAHDVDGLHVYTMNRADVASAAMSALRQDSANR
>A0A3P3XQQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured spirochete|TrEMBL
MPATSYCGVTMHNDKPSVNTSRARVLDTLASGLASRPVSGRAPRRCISIEMVPPPRGGDL
DSIMAAMETIAPHRPSFVSVTDHPGGKAWVDSGEGPKRVALRTKPGTLGTAVALRDAFDI
TAVPHIVGGMADRLDVEDLLIDLHYANFRDIFVVMGDDRYAPAALPPGGRAGRMGNGPDG
YNHARDIVEHVVRLNRGEYTPPSEGKPTDFVVGVAAYPQKHFAAANPETDFEHLVEKIRA
GASFVITQMVFEAGPYADLVRRLRDAGVGAPVLPGIKPILKASSLDMIPRTFFVDIPPLL
VAALREARSPAEERAAGIAWTVKLCQDLLDAGAPGLHFFTMGRGVGTRWILDALFGTPGG
KV
>A0A2G4TYR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia bercovieri|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLRDIAADYWSSGIRHIVALRGD
LPPDSGKPEMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A5B7SKJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aggregatimonas sangjinii|TrEMBL
MKITDHIKEAKGETLFSFEIIPPVKGHKIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
RNGLLDKKLTRMRPGTVGICASIKHKYDVDTVPHVLCGGFTKEETEYVLVDCQYLGIDNV
MALRGDAMREEKYFQPAEGGHEYAIGLVEQLNDLNCGNYLHDTMEGTNCADFCIGVAGYP
EKHLEAPSLQSDLKRLKEKVDAGAHYIVTQMFFDNKKYFEFVDAAKAMGIDVPIIPGIKP
IAVKRHLNLLPQVFRIDIPQDLIDAVDGCENNKAVRQVGIEWAIQQSKELKEAGVPVLHY
YSMGKSDNIHAIASALF
>A0A1L9BR25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. SM22M-07|TrEMBL
MSRQTPKISFEFFPPKTLDASFRLWETAQALAPLGPEYVSVTYGAGGTTRKLTHEAVTTI
NRQFGLNVAAHLTCVEATREETMKIVQDYADAGIREIVALRGDAPKGSDGFSAHADGFAN
SVELIEAIAARGDMTIRCGAYPEPHPDSADTDADVAWLKRKIQAGASSAITQFFFDADTF
FRFRDKCAATGIDAPIVPGILPVQSWAGTKRFAAMCNTTVPDWAHEAFDLAALDGPEAER
QLATGICVDLCETLIAGGVDRLHFYTLNRPELTRDVCAALGIRPKGGLEAVA
>A0A7W7QLS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium saharense|TrEMBL
MALGRSSVFPERVPTVRELLATGGRSFSFEFFPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGGTRDRTVEIVERLAHETTLTPVAHFTAVNHSLRELRHLVGRFAGAGVRNILAVR
GDPPGDVTGEWIRHPEGVQYAEELVRLIRQSGDFCVGVAAFPYKHPRSVSVEADTEHFVR
KCRSGADYAITQMFFRAEDYLRLRDRVTARGCETPIIPGIMPVTQMSTIARSEQLSGAPF
PPEVAARFEAVAHDPAAVRSLGIEHAAELCQTLLDEGAPGIHFITFNRSSATREVFQALD
VRTGAAPLAV
>H1C6N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 7_1_58FAA|TrEMBL
MMDIRTYLSQGKPLLFDGAMGTYFAAHPGRAEERCERANLTRPEEILRIHRAYLQAGCRA
IKTNTFAISGDLSDGNDETACDIVNAACHLARQAAQPYGAYVFADLGPAPRDHSRAPADL
YQTQAQWFLEQGVTHFLVETLSGDEGLPELAGWLKEKNPDAFLMVSFAVDHSGMTSAGRL
GSELYRFASELAGVDAVGFNCVSGPRHLLKYIQTLELSDKPLTVMPNAGYPTVLGRRTVF
GGQPDYFAGQIAQIVQAGASIVGGCCGTTPEHIAQTAQALKEPLPKCTVSAPKKLLKPAA
NASNSLWEKLEAGKRVIAVELDPPVDDDSAGFWEGVQALRGSGADAVTIADCPIGRPRAD
SSLLACKIKRDIGIEPLPHMTCRDRNLNATKALLLGLSMEGVHNVLVVTGDPIPTEDRNE
VKSVFNFNSRKLARFVHMLNENTLRTPFRIYGALNLNARNFDVELRRAQEKEACGVSGFL
TQPVLSAEALDNLKLAHKTLRGKILGGIFPVVSHRNACFLNNEISGMRVCDEIIHLYEGK
DRDAAEALAVTVSTAIAKEIFPYTDGYYLMTPFRRVALMEHIIQNIQQSCIS
>F8W9T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Homo sapiens|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQL
>B3PTY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium etli (strain CIAT 652)|TrEMBL
MALKNEAQARNIGISFEFFPPKSEEMEGQLWNTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRRAGISIPIVPGIMPIQNLTQLKRFAGACGAVIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIRDFHLYTMNRSPLVSAVLDNLGLSRRPAKNAGAAA
>A0A2P8ALB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. MH33|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRHVIGRLASVGVRNVLAVR
GDPPGNPGGEWIEHPEGVRYAEELVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQLATIERSVQLSGAPF
PPALAARFAEVADDPEAVRRLGVEQAGEMCAKLLDEGVPGIHFITLNRSTATREVWQRLR
ADARV
>F3MXX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus rhamnosus MTCC 5462|TrEMBL
HQVGDFDVVGACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFFDNQVFYQFRERAA
LAGINVPIEAGIMPVINEHQIERMATMAGVHLPPKFVAMMQHFSGNKEAMRDAGIAYAID
QIIDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A0J9E6I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rhodobacter lobularis|TrEMBL
MPRLSFEFFPPNGLDASFRLWDAVNELAPLEPHFVSVTYGAGGTTRDLTHEAVGTINSHY
GLNVAAHLTCVDATRAETLEIAQGYAEAGVTEIVALRGDPPKGVSHFEPHPDGFADSAEL
VAALADMNKFHIRVGAYPDPHPEAQLPGADVDWLKRKIDAGAGSAITQFFFEAETFFRFR
DACAAAGIDAPIIPGILPIENWTRMQRFAQRCGAHVPGWLADAFETAIRDDRHDLLAIAT
CTELCSDLIEGGVEDLHFYTLNKPSLTREVAHALGVTPKLALRDVA
>A0A5A9W4K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrincola tapanii|TrEMBL
MTQTLRTKFSDPQQGVYFIGTTPPKRSTDDAQMLEIADKLLARLDSLEYDGLIVYDIQDE
SSRIDTPRPFPFMETRDPREYSRLLSQRSGHETLTYKSVAQRDAKEFSAWLDETQRDFGL
QHIVLVGSPSSEGEIRLNLNQAYEVLAQHPQDYHLGGVTIAERHASKGNEHLRLQQKAQQ
GCDFFVSQAVYNAEATIDLLQSYAQLCEETGETPKRIIMTFTPCGSAKTLEFMQWLGISI
PDATQARILQAEQPLTESIRICQDNLEQILEACAGLNLAWGLNIESLTNRKEEIDAAIHL
YRLLKATLELTLAERSLELDPL
>W3Y3E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. AS16|TrEMBL
MTLREKHKNGQFTITVELDPPKSSSAQKVFDQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHHEGIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAKAV
FEVDSMGLLDISKTLNSGKDMAGNDLDEPTSFYIGTTGNPGAEDLEIERQKLAAKIEHGA
NFVQTQPIYDLEQAKRYIDAMSGFNIPIMLGLIPLKSFKMATYLHEKVPGISLAQEILNR
VEKGGKEAGTEIAIETLEEIKKIASGVHIMPLNDIDTTLHIIDHV
>A0A4R2H9U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter psychrotolerans|TrEMBL
MKIVDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QDNGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADHSFIPTKGGHCYATDLIQHIKNHNEGKFLHEDIETFKSDFCIGVAGYP
EKHFEAPNLNADFKYLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPDELTDALSHAKSNAEAKEIGTEAMIKQCKELMDFGAPVLHF
YTMGRPEQTKQIAKAIF
>A0A7X5WCN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
LEVTEPARKLRVAGVDAVSIVESPRSRSRMGALSAALIIEREVGIETIVHYTCRDKNMLG
MISDLLGAAAAGIRNILVVSG
>A0A2V7MWC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTITLRDLLNDGKVHVLDGAMGTMLYSKGFLLNVCYDELNLKQPKLVQEVHEAYVRAGAE
ILETNTFGANPLKLKSFGLADETEQINQAAARLARAAAAGRASVVGAIGPLGVRIEPFGA
LARDEACAHFSRQVKGLLAGGVDGFILETFSDVEELHAALRAVQSLSDLPVIAQMTIGDD
GLTHYGTGPETFARQLTEWGADVIGVNCSVGPAGVLEAVEKMVKVTDRPISGVPNAGLPR
DVGDRKIYLASPEYMASYARRMIEAGARLVGGCCGTTPEHIKKIRDYVASVVPRHQPAVV
SRDTIAAPAGVAEVPLAARSRWGAKLARGELVTSVEIVPPKGVDATPMLAQCRALKAAGV
DAVNVPDGPRAQSRMGVLPSAILIQREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRN
ILIITGDPPKMGPYPEATAVFDIDSIGLTNLVFRLNHGLDPGNNPIGAPTQWAIGVGVNP
GAVDLDRELSRFAWKVDAGAEFAVTQPVFDPQQLAAFLKRVEQFKIPIVAGIWPLLSLRN
AEFLANEVPGVSVPDSVLARMRQAQEKGKEAALAEGVKIAREMFEQVKGGVQGVQVSAPF
GRVEVALEVFG
>A0A1N6W2P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia flexa|TrEMBL
MGLLEDLQSRILIGDGATGTLLYSHGIDSCFEELNITKKEEIQRIHRAYVEAGADVIQTN
TYAANYQKLARYGLEDAVKDINISAVRIAKQAAKKDAYVVGTLGGIRSFQKNAISTEEVK
RSIREQLFWLLNEGVDGLLFETYYDFEELKTVLSLARKETSKPIITHVSLHDIGVLQNGT
SLYDAFQELESLGADVVGLNCRLGPSHMIQSLEEVPLLDRAFLSAYPNASLPAYVEGKVE
YATNQEYFVESAKAFRNQGVRLVGGCCGTTPAHVQAMSQALKHEKPITQKKVKIRPVVEI
KEQEQTKEPHLHDLVKERRSIIVELDPPKQLGPTKFLDGAKALHKAGVDAVTLADNSLAS
PRVSNLAMASLMQQQTDARPLVHITCRDRNLIGLQSHLMGLHTLGINQVLAITGDPSKIG
DFPGATSVYDVSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVVRL
EKKISCGAHYFITQPLYSTKQIEEVYEATKHLDAPIYIGIMPLTSARNARFIHHEVPGIK
LSEDILARMDATGDDRIKGEVEGLAIAKDLIDTAYELFNGIYLITPFLRYEMTEILTRYI
NDKQLVTTERKN
>A0A7H9BMA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinibacter bivalviorum|TrEMBL
MQSSLRPISFEFFPPKTDEGASKLATTRQQLAQFKPEFFSVTFGAGGTTQEGTLRAVLSI
REAGFAAAPHLSCIGSTKENIREIVQQYKDHGIRHIVALRGDIPSGMVGLGEFRYANELV
SFLRAEFGDWFHIEVAAYPEFHPQSESAEADMRNFVNKVRAGADSAITQYFFNADAYFRF
VDEVQARGVNIPIVPGIMPIQNYSQLQRFSDMCGAEIPRWLRLRLQAYGDDMASIRSFGL
DFVTELSDRLLSGGAPGLHFYTLNSAGAVSTVCQRLGY
>A0A6L7QLH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MQQTATLRHLLEETDRFITCVELVTSRGTLADRGGKRVLEMAQALAADPRFDALSITDNP
GGNPMISADALGTPLKESGQEVIIHLSCKDFNRNGLMGQAWKLADGGFDNILTLSGDYPI
AGYQGQSSGVFDIDSVGLLQLLSDMNEGHFEDASPGRKPRPLKPTRFFLGAVVNNHKRLE
AEVMPQYFKLAKKIRTGARFIINQIGYDARKQDELLKYMALHGLRVPVIANVFVLSGGVA
RFFHAGRIPGVEVTDELLAVAQKQAASPDKGRAFFLEFAAQQCAIARGLGYRGVYLGGHI
GAEEYGRILELAAQYAAD
>A0A7V9R4B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MEPFRDILETDRIHVFDGAMGTMLYAKGVYINRCYDELNLTNPDLVQEVHSEYVQAGADI
IETNTFGATAHNLNQYGLADNLREININAARIARAAADERAYVAGAIGPLGLRIEPYGPT
SFDEAKDMFKVQAEALLEGGVDLFVLETFSDVSAMRQAIRAVREVSDLPIIAQMTILTDG
NTSYGTTPELFTARLDEWGADVIGLNCGVGPAIILSALEKMRAVTKKKLAAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRFIQAGAKFIGGCCGTTPAHIKLISDAVRAASPRAQKVVMT
SGALAHITDAAPTDLKLVPPAERSHWSRKIVNGEFVTSVEVLPPKGVDAEKTLASIRLLK
DAGVDGVNIPDGARAQSRMSALATAVLVEQQIGIESVLHYCCRDRNLLGMMSDLLGAAAL
GIRNLLLITGDPPKMGPYPDATAVFDIDAIGLTNMVNKLNHGLDIGNNPIGQPTAFCIGV
GVNPGAINLDEEIRRFEYKVEAGAQYAITQPVFDTDQLRDFIKAIEHVRIPIVAGIWPLV
SYRNAEFLHNEVPGVRVTPSIMERMRTASAVSKEAGRDEGLKIARESLLEVRDLIQGVQV
SAPFGNVKYALEVFGALDEFLPAKTAETASDRN
>A0A6G7P706|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. JB150|TrEMBL
MALGTASTRSDHAPTVRDMLATGKTTYSFEFYAPKTPKGERMLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVRHPEGLTYAAELVELIKNSGDFCVGVAAFPAMHPRSTDWDTDVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLERIPSLTNAAF
PAALKERILTAKDNPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A2G4IEY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MPVVPSPHRSAPSSLTPHRHQQALPSPFSVSFEFFPPKTPESEEALWRAITRLAPLSPKF
VSVTYGAGGSTRERTHRTVKRILAETELVPAAHLTCVGSTQSEIHEVADAYWESGVRHIV
ALRGDPSTAGARYEPTPDGYAWASDLVAGLKARHDFDISVATFPEGHPEARSLDAELDNL
KRKIDAGATRAISQFFFDHGTFLRFVDRARKAGITVPIIPGIMPVTNFGQMTKFAEMAGA
TVPSAMALMFDGLENDVETRKLVAVTIAADLCQKLADAGVKEFHFYTLNRADLTYALCHI
LGLRPVR
>A0A1H0SJZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora xinjiangensis|TrEMBL
MTTNAHQQLQRYLRNARYEVLPLRGVVEQVRELPAGTTVTVTSSPAKGTEATLDTAARLR
DEGMHVVPHLAARLVRDSAHLTDLMARVDDLGLTEVFVIAGDAERPAGRFTDALSLLRGL
EEIGTRPYRLGITGYPEQHAFIPDRMTIQATDEKARYADYIVSQICYDPNTIASWVKGMR
ARGVELPVYIGAPGSIDPSKLLRISMKIGLGQSMRFLRKQHGVVSKLLTRYTPENVFDEL
SPYIVDPDYNIAGWHLFTFNEITKTRQWVVEMADRLQEVPA
>Q31EK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenovibrio crunogenus (strain DSM 25203 / XCL-2)|TrEMBL
MQSQQKYEQKLSLEFFPPRTDKGVEKLQTVIEELGTIHPEYMSVTYGAGGTTQNRTIETV
EYIQTQTEFDAAPHLTCIGASEESVLDLLDRYEAMGIKRIVALRGDLPSGMMDPGEFKYA
SDLIAFIRQERGDTFKLEVAAYPETHPQARNCDIGIKWFKHKVDQGADSAITQYFYNVDS
YLYFIDNCERSGIDLPIVPGIMPITNYENLIRFSEGCGAEVPRWLKCRLESFGDDTESLK
AFGEDVVTELSQRLLDAGAPGLHFYSMNQSAPTLNIVNALTFKNT
>A0A1H0WLV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora xinjiangensis|TrEMBL
MTRVVDRLQPGRTVFSVEFFPPRNDDEEQILWKAVRELEPLDPAYVSVTYGAGGSSRDRT
IRTVGRIAQETTMLPMAHLTGVDHSKDELRHVVGSLANEGIRNILAIRGDPPGDPMGEWI
PHPDGILYADELVRLVRSCGDFSVGVAAFPHMHPRSTDIETETDHLVNKIRAGSDFAVAQ
LFLQPEYFLRLRDRLAARDCHVPILPGVMPITTPKVLSKFQHLAGVPVPAEVSNVLDPLA
DDPEAFRAAGIELSTRLCERLISEGVPGLHFYSLNRAKATREVVDNLGLAEVVPQPA
>A0A1H1VZH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillaceae bacterium GAS479|TrEMBL
MSSTLKDKLLRKESGILTYGMTPPKSSHPPEKIREIADKQISRLKDTGIDGLVLYDVQDE
AERTDKDRPFPYLEALDPTEYYNSYLKQELGVPAIIYHCVAIEGPDKLAKWILQDRDEQR
YTVYVGASSSRQQVQIRLPEAYRMSGILNEKLMTGGVVIPERHRSKGDEHMRAQAKQESG
CGFFISQATYDVEASKSFLSDYYYDSRKNGTEMVPILFNIAPCGSAKTLEFMKWLGISIP
KWLENELMHSQDILDKSVQLSRQVFLELYRFGIEKGIPIGCSVESVSTRKVEIEASIQLL
KDIRQDMQSISEQLTTV
>A0A7X8MC59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MALKEKIESKQLILCGEISPPQSCDGDVIREKARYFKGLVDAVNITDNQTAIARLSSIAS
AKILLDEGVEPIMQMTCRDRNRLAMQSDLLGAAALGLHNLLCVTGDYPTFGDQPEAKAVF
DLDSIQLIAAVSHLNQGLLLSGHVMKKAPDFLIGAAANPCGRPLEMRLIRLYKKIQAGAR
FIQTQAVFDLELFSRWLKQAVAWGLTEKAVILAGVLPLKSVKAVRHMQQVPGVRIDEGYV
QRMQQAKDPQEEGVKIAVEIIHALVRMKGVAGIHLMPVMWESITPTLLREAGWTTINQGE
RP
>A0A7C3MMJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MAGNSFGAVSPPSSEKTDSLSIFLESLSGRRPALWLEVAPPRGINPEPLLKRLSALVGHA
DAINLTDNALGRVKMSSIVFGSIIRTRLGIPVVVNFSCRDRNRLALKSDLLGAAALGIDA
VVALTGDRIAPGDPSGAHAVHDLDAFGLLEMIAMLNRGDTGEGRALLKVLPNLVAGAVAN
PNRGNIEREFELLERKAQAGARFVITQPVFEVETARRFIARARAYGLATMLGVMPVKRES
MAAYMRERVADLKEAAHHLDRYAGMSEEEVRAESLAQNLALMKALAAEVAGFNIMSGGGP
SLAIELALEFSRWRKESGR
>A0A851LJW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corythaeola cristata|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQESGEK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETVLHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAADL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSEAFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A4Z0QLW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp. Sb-LF|TrEMBL
MENKFKESLLDKNTLSVTWELVPGRGANEKAQESAIFSAEQAAKGGRIHALTITDNPGGN
PAILADYLGMEILKMGIEPLVHFTCKDKNRNQMESQLYALDRANVRNLLVMTGDYTVSGF
KGRPKPVFDLDPSNTLQLISDMNKGLEVAGMKGPTFHKPSDFFAGAAVSPFKSTEAELMV
QYYKMKKKIAGGAQFIVTQLGYDARKFHEVLQFLKVNKLDIPVVGNIYILPFGAARVMNQ
NQLPGCVVTDKLLAELDAEKVAPDKGVGARLLRAAKMYAIMKGMGFAGVHIGGHNIKYEQ
VEYVLDKGEELSKNWQDLVREFDYPQTDGFYYFEKDEKTGLNTDRPANRNNRPLDAPANV
GYTMMRGMHSLMFTPDKKLFPMLRKMYSSVEGKKNTEKRLHAIEHISKVVMLDCKDCGDC
AILDLAYLCPMSQCPKNQRNGACGGSLNGWCEVYPNEKKCVWVRAYARLKKYGEEANLDV
PPVPPANWDFYQTSSWSNFYLGKDHSAPLLGIKRPVNKVSETKK
>A0A7X3PY14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0667_bin_9|TrEMBL
MHIAEVFRQSQPAISFEFFPPKSEAASESLFHTIQKLIPLKPAYVSVTYGAGGSTRDLTH
DLVVKLHNETNLTIVSHLTCVQSSRDEIFRILQRYDEHSIRNIMALHGDPPSQEPCDPSG
QDFRHAVELVAFIKKHFPHMGIGVAGFPEGHPDTPNRLQEIEYLKAKVDAGADYVCTQLF
FDNRDFYDFCERCQLAGIHVPIIAGIMPITSLQGMKRMAELALGARFPGRLLRALASAKD
DAQAEKIGIHWATEQVLDLLDNKVLGVHLYTLNKSRASLQIYETLGLQRVDMLME
>A0A8I0BLE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp|TrEMBL
MALSLKEKIEDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQARPFAFKQTVDPREYSHLLRDLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDL
QNVVLVGSPSSVGDIKLSLPDAYKAMAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGITPQRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASIHL
YRLLKAIMELNLAEKLIA
>A0A7W0PT57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexia bacterium|TrEMBL
VDAINVADSPMARVRMSAMTLCYLIQHEVGVETIIHFTTRDRSLMGLQSELLGAHAAGVR
NILALTGDPPSLGTVPVSSGVFDVDSIGLIRIIKEMNGGSDATGSSIGRTANFTIACAVD
PNKPDLEDEARRLRQKIEAGANFVMTQPIFDTSVWTNFLNVFGAERLPIPVMIGILPLQS
TKHAEFLYNEVPGINPTENSRERMRLAGANGRAEGVRMAQELLEELVPHAQGVYLMPSFG
RYEVAAEVLDVLPG
>A0A7V1DQ14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MRICHLLQQKRPVFSFEFFPPKTPQGEAALFRTIEALRPLAPGFVSVTYGAGGSTREKTL
DWVARIKHELGIEAMAHLTCVGSNRDEMRAMLQRIDDLGIENVLALRGDPPRDQPGFQPI
PDGFAHASDLVRFIRTEGFSFCLGGAAYPEGHIEAPDLETDLTYLGEKVAAGVDFLITQL
FFDNRFFFDFVERARSRGIHVPIIPGIMPITNVAQIERFTRLCGASIPPALQARLDAVRH
NEDAVRSIGIEHAVAQCRDLLAHGVAGIHFYTLNQSPATRAIVEQLQRGPVACPAS
>A0A2B2C3X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS073361|TrEMBL
MSFLEKLKNQILIADGAMGTLLYSYGKDSCLEELNLSQPDHIQSIHKAYIDAGADVIQTN
TYAANYLKLQRYGLEDSVKEINSAAVRLAKQAASKSNTFVLGTIGGNRGVKPDSVSIEEL
KRSFREQLYCLLLEGVDGLLLETYYNLEELETILTIARKETKLPIIAQVSHQEPGFLQDR
TPVNDALQRLEALGADVVGLNCRLGPHHMLLALEQIELPKQAYLSAYPNASLPAYTDGKF
HYEGDADYFRNSARAFRSQGVRLLGGCCGTTPEHIKAFAAELKNSVPITEKIVKLKPKRI
IVDQLSPQREFTPLHEIVKERPSVIVELDPPRKLDTTKFFEGAKALKEAGIDSITLADNS
LATVRISNESLGYLVKEKLGMRPLIHIACRDRNIIGLQSHLMGLHTLGMNDVLAITGDPA
RVGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTSFSIAAAFNPNVRSVEKAV
KRLEKKIQYGADYFISQPVFSEEKLIEVYEQTKHLDAPIYIGLMPLTSSKNAEFLHNEVP
GIKIADSIRNRMAMFNDNPEQAAREGIEITKSLIDTALDLFNGIYLITPFLRYELTAELA
LYTRQRSSELRRSNYAENTIY
>A0A2T5U0K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas faeni|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGISFEFFPPKSEKMDAQLWEAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPTEKVAAA
>A0A1F9NPL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium GWB2_56_26|TrEMBL
MELKTKSKLEKVFKSGQLAVTSECGPPRSSDPEHIIKKGHIIKNHVDAINITDNQTSVTR
LCSLASCIHLKLEGMEPVLQMVVRDRNRIALQSDILGAASFGINNMLCLSGDHQSFGDHP
KAQNVFDLDSMQLIQTVRHMRDEGKFLGGEEIKVPPNLFVGAAANPFADPFKIRVPRLAK
KIAAGAEFIQTQCVYNLEKFELWMKGVVERGLHEKVFIMPGITPMRSVGMAKYMARAVPG
MDVPEELIKRLSGVPKEKQAEEGITIAVEAIQRLREVKGVAGFHIMAIEWEDKVPEIVER
AGLYPRPKFD
>A0A416UAU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. AF17-9LB|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>M3BSG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces gancidicus BKS 13-15|TrEMBL
MTTFSFEFFPPKTDRGERTLWDAIRRVEALRPDFVSVTYGAGGSSRDRTVAVTRRIAAET
TLRPVAHLTAVGHSTAELRRIVGRYADAGIRDVLALRGDPPGDPNGPWVPHPDGFTHARE
LVELVGLLGDFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFHVEDYLRL
RDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSGAAFPEDLAHRLERARDNPAAGHRIGV
DHATAMAERLLAEGAPGLHYITLNRSTAALDIHRNVQTLGSLSAH
>A0A316B5C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter iranicus NCPPB 2253 = VKM Ac-1602|TrEMBL
MTPARFEIIPSNDIAERAERAFPDPSAVTLTVTSLPKHGTQRTVDCAVELAGRGFQVVPH
LAARTIEGRDALQRLLARLGDAGINEAFVISGDAREAAGSYATSLELIRDARELAPSLAL
DIAGYPEGHPHLSAESIERHLHERAPFIRSVVTQMCFDVDAVVRYADRLREQGVTADVWA
GVPGPVERSKLLTLGARIGVGASLGFLKRSTSVAGGLLHGRRFDPTAFVARLDSAAGDRL
AGLHVYTFNEVDALATFA
>A0A511UX12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halovibrio variabilis|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARKPKFFSVTYGAGGSTQARTRQVVR
EISESGITTAPHLSCIGSEKAQLRDLLAQYREEGIDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFEIAVAAYPESHPQAANLDRDVENFARKMKAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCERLLDGGAPGLHFYTLNQAAPVLKIVDNLTD
>A0A0Q7MH37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Root483D2|TrEMBL
MAHIDENPLGRHLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNSKFLSGRKLTTPPQVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMNKVRDLGFDEKCFILVGV
GPLASAKTANWIRNNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIKGVSGLH
VMAYRQEEYVAEIVHESGVLKGRTPWTREANPGDSRVAERLDAIRDGKQENQEEMADVAA
HRQH
>R6V7L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:227|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELLEEAKTYLQGVHAVNVTDNQSSVMRLGSLAM
CKALKDAGLNPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAIFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKVPELLKQAEI
>A0A7H8IVL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NA02950|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEHTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAIDHSRAELRNIIGQYADAGIRNMLALR
GDPPGDPMGEWIRHPEGLGYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVN
KCRAGADFAITQMFFFPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVRQIERFAKLSNAAF
PPELAERILAVKDDAAAVRSIGIDYATELCARLMAEEIPGLHFITLNHSTATLEIYENLG
LHQRSS
>A0A849ZHZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sumerlaeia bacterium|TrEMBL
MHIRDVFHRDRVTCSFEFFPPKSAQGFQTLFESVRQLESLKPSFVSVTYGAGGSTREQTH
DLVVRIKRETALDPIPHLTCVCHSERDIARILERYAEARVSNILALGGDPPRDLPGHGRA
MDAFQHASDLVAFIRRFNEGGRHADPRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAG
ADYICTQLFFDNRDFYDFRDRCELAGIQVPIVAGIMPITGESNLRRMADLAAGAHFPAPL
LRAVARCQGNDEAIKSVGIHWATQQCFDLLDHGVRGLHFYTLNRSDATVQIYRNLGLRDS
GVLRQAG
>A0A7S7MTR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. OST1909|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQSEPSLAVWNNLKLPR
>A0A3R7ETW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MKTMFREVLKSNVTPVTYEIWSPKGCVINQHIKDIKDFKDRIDAVNVPDNPLSTLKVSSI
AYAKIVMDELKVDAIPHLNCRDRNLLALQSDILGAHILGLRNLFIIGGDKPSGILKPKEV
WETTSIELCRIVKGLNKGFAYNDESIKIEGKTDFLVGGTIIFDRKNEVETVSKKIEAGFD
FFQSQITFNPNLVLNFFEKAEKQGVNLDKPVLIGLAPQPSEKALKKVLSFLHVEVSENLL
KRLSQSGDFQGELISVLLEAADEIKSALSPKYKIGFHIMTLGCDYLGKKIIEGLRRK
>A0A523VTI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MTGEAYSELMKQINEGKFVFTGELEPVKTTKLDDVIEGAKTLKDHVVAINITDNPTAFGY
MNALVPSYMIQKEVGVEAVYQMTTRDRNRLALISDVLAAGALGIKNILALTGDHTTVGDT
PQAKPVFDLDSATFVYMLRKMMDEGVDLNNNEIENPPKFNIGIAAAPNANPLEPELLKIE
RKVRLGVDFVQTQCVYSVEQAKNFLDAASYIDVPILVGIAPFKSISMMKWMVKYVPGIKV
PEEIQETLHKAKKTGGKEAVYEVNIEIFGELLREIRKTTNAAGIHTMAIGFEWIVPKIIE
RARL
>A0A2A2A7U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vandammella animalimorsus|TrEMBL
MSASAPSQPQAPRAALSLEFFPPKTEAGALKLRATRQALYPLQPQFCSVTYGAGGSTQAG
TFAAVREILAEGQQAAAHFSCIGATREKLRAELAELQAMGVKRLVALRGDLPSGYGLGGE
FQYASDLVAFIREETGEHFHIEVAAYPEMHPQAASPEKDLQAFATKVRAGANSAITQYFF
NADAYFRFVDEAQRLGLDLPIVPGIMPIHAASQLLRFSDACGAEVPRWVRSRLQAYGDDT
ASIQAFGLDVVTKLCQRLLAAGAPGLHFYTMNQSTLVLEIARRLGLPTH
>D0RM84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora infestans (strain T30-4)|TrEMBL
MIQWITQCKDAGISIPILPGYLPIQNYSSFCKFTSWCKTRVPEKVLAALDAIKNDDAAVR
RYGTQLAVETCQRLLAAGVNSLHFYTMNLAATVTQVLEELQLQPARNQRELPWQSTLQRS
TVEGEQVRPIFWSNRQASYIARTAAWDEFPNGRWGDRTSPAYGELSEYYLAFKRPKLKRT
ELWGTPQSEQDVWNVFVRFIDGHVKQLPWCEQALSLESAAIRENLQWLNSNGFLTINSQP
RVNGASSSDPLVGWGGDEGIVFQKAYVEFFVAPEKMEHLVKVMRRDHPHLSFHALNRRGD
EHRNTPLHSVTAVTWGVFPGIEIMQPTVVDSDSFAAWKDEAFELWQTQWASAYPEVSHSR
EVIQHIYDSYFLVNIVDNDYANDDSDIFSIFTQIITEAMDKEQLRARVLELEARREKMFD
TLASFQSQQEELNGELRAAHSELAGVRGENLQLKEKVRQLQAQLALASL
>A0A6G0IQD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Larimichthys crocea|TrEMBL
MVNHVQRLDCSMQSCKSDSSGASNSGGESSKESSRCSTPVLDADRADRLRDKMRRRMESG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGYLGKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAI
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVITQLFFRAESF
LKFVDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIQQAVEMCHVLLDSGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLQMWGEELKNEESVFEVFTCYITAQPNCHGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKSSTDPIVGWGPAGGYVFQKVRELFVLFVRLVGMDREWGGMDREWG
LLSDMDL
>A0A6N3UZZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKIKDLYTPGRTVFSLEVFPPNKNFPIETVYDAIEGLAAINPAYISVTYGAGGNRANRST
CEIASHIKEKYGIEAMAHLTCINSTRDDVDFMLDDFAANGIENILALRGDNKPDEEPKND
FPHASDLTAYIASKGNFDIAGACYPETHVDAESAEEDIKNLKIKVDAGASHLVSQLFFDN
SCYYDFEKRARAAGIDVPIAAGIMPVTNKKQIERMVTMCGASLPSKFVKMMQKYENDPEA
LRSAGIAYAIDQIVDLISNDVQGIHLYAMNNPAVASRIYNGIKDLL
>A0A537CG71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MRLSDRARHHNLVTVELIPDRVVPSDLALLRGRVDAITVPALRNGHNDPSYPKSFPVTPQ
RRSLASASIINRAGITAVPSLTCRDCRRSDLSTISNQVEEGLGNVLIVYGDPYPEPRPGT
YEFAKTNQLIREISSLNGGNDPCIGAVTNQHANNRESEISRTLSRVDAGADFIVTNVAFD
AQSVLGHRDSLLEAGLNVPLFIQVSIPLSLDNVLFVGQKFDIPVPAHVRKKLLDDPAGGS
LAVAAEAYEALRGEANGIHFSYLFRQRNPIPAYRHLLETIGIAGPTLAPLSTSAVKTYPV
A
>A0A537DPV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MRLRLSDRARHHNLVTVELIPDRVVPSDLALLKGRVDAITVPALRNGHNDPSYPKSFQVT
PQHRSLAAASIINRAGITAVPSLTCRDCRRSDLSTISNQVEDGLGNVLIVYGDPYREPRP
GTYEFSTTNELIRGISLVNGGCDPCIGAVTNQHSNDRESEVSRTISRVDAGADFIVTNVA
FDSESVLAHRDSLLEAGLNVPLFIQVSIPISLDNVLFVGQKFDIPVPVQVRKKLSEDPVG
GSLAVAADAYEALRGEANGIHFSYLYRHRNPIPTYLHLLETVGIESPTLAPIIASAVRT
>A0A132B1L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mollisia scopiformis|TrEMBL
MHIKDILAGSEQSGQPTFSFEFFPPKTAQGVQNLYDRMDRMHAFGPSFIDITWGAGGRLA
ELTCEMVGVAQTTYGLETSMHLTCTDMGEDKVNEALNNARNAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVKHIRAKYGDHFDIGVAGYPEGSDDQKDEAILLEHLKEKVDAGATF
IVTQMFYDADNFLRWVSEVRAKGITVPIVPGIMPINTYSSFLRRANHMGCKIPPEWSAAL
EEVKNDDAAVRSIGTGLVAEMCRKILAGGIHHLHFYTMNLAQATRMVLEQLDLLPSVHRP
LTQPLPWRQSLGLGRRDEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDARSPAFGELDA
YDIGLKGTNEQNRKLWGEPKTIKDIANVFVKYLENGVESLPWSEAPITNEADIIKADLIS
LNQRGFLTINSQPAVDGVKSSDPVYGWGPRNGYVYQKAYLELLVPPNLIGELIARIERDP
ELTYYAVSKASPLKTNSADGPNAVTWGVFPCKEIVQPTIVERISFLAWKDEAFRLGTDWA
RCHSSLSPSRHLIENMMETWFLVNIGNSFLLFYVGMNLALTIQP
>A0A416ZY62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM46-21|TrEMBL
MKIRDIIGQEKATLSFEVFPPKKDTDFASVEAAALGIAALRPSYMSVTYGAGGSTKGHTI
KLANEIQEKYGVPTIAHLTCVCANKDSIRTALSEMKNAGIENILALRGDIPKNYDGQVFT
DFAHASELVKLIKESGDFCVGGACYPEVHPDSANKQDDIANLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRIREAGIAVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEVAAGIQANLSDILLV
>A0A3D2K5A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNQYNVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKETTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>A0A1L7FUT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas alcaliphila JAB1|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLPR
>A0A2T6FGA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrio sp. 79|TrEMBL
MSDSQLRLSFEFFPAKTPEGKAKLINVRNELNFFNPDFFSVTYGAGGSTRDNTKSLVTQC
VRDGISTAPHLSFGGDDEETIKALIQEYKDAGVDRIVALRGDMPSGMGGGFQLVYANELV
AFIRKHFGEHFQLEVAAYPEIHPQAKNYSDDVRYLKGKFDAGANSAITQYFFNPDSYFFF
IDQCQKAGITQPIYPGIMPIINYRNLTRFSDTCGAEIPRWLRKALENYGDDEASLKAFGI
ELVSELCETLLENEAPGLHFYTMNQTEPTAQIVRNLGLVPVE
>A0A2E4R0Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinovum sp|TrEMBL
AFERATRDGRHDLLSTAIGTELCDTLRSEGVDTLHFYTLNRPELTRDICLALGLTAKPSL
KAVA
>A0A350H442|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MQISKLFDGDKTVLSYEIFPPKRNDSIDKIYDTIEKLSDLNPDFISVTYGAGGNIADSKT
ADIAQLIKDKYNIESVAHLTCINTGKEELDYILNDLESKGIENILALRGDINPDIKPKKE
FKYASELATYIIKRGGFYVSGACYPEVHVEAEDSIADIKNLKKKVDCGVSHLISQLFFDN
EVFYAFKDRARAADINVPIEAGIMPVTNKKQIERMVTLCGASLPAKFVKVLQKYEDKPEA
LVDAGIAYAVNQIVDLVANGVDGIHLYTMNNPYVARKITESVKNIL
>A0A416I0U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium AM59-13|TrEMBL
MKIREILAQDTATISFEVFPPKKSTDFENVETAALGIAALQPAYMSVTYGAGGSTKGHTI
VLASEIQEKHNVPTVAHLTCVCAEQGSIRAALDEMKTAGIENILALRGDIPKDFHGEVFT
DFTHASDLVRFIKENGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIVPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQKNLSEILKA
>A0A2K1P8B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrotoga mexicana DSM 14811|TrEMBL
MKIVDLIEQSNKPILSFEIIPPNVGESIDSIFNVVDNLIEFSPKFINVTKHANEIEYIEE
KGEIIKIIKKKRPGTVGVSASIKHRYNIEVVPHLICTGFNRYQLEDILIDLNYLRIENIF
VVRGDKKRYTWKETDEYEHASQLVEQITNMNKGIYTCPTKEHNPTNFCVGIAGYPEKHFE
SPNFEKDLEYLKLKVDMGAEFIITQMFFDIEYYKNFVNKVRELGIEVPIIPGIKPLGSKK
SLYNIPKTFHVNIPKSIVEEFEDAKSSQDEYRIGVRHGIKLIEQLLEGGVPPEFDS
>R6RN74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:58|TrEMBL
MAHLTCVSSTREHVMGVVERLRENGIENILALRGDIPSDGHVEKDYSHASDLAAELAAMG
DFCIGGACYPEGHPESKNKAEDIRYLKEKVDAGCSFLTTQMFFDNDLFYNFLYRIREAGI
AVPVVAGIMPVTNAKQMKRILSMSGTVLPTRFKMLLDRFGDDPAAMKQAGGAHAVSQIID
LVANGIHAIHIYSMNKPDVAEQIKSSLSEILV
>A0A7C6KLY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MGTLLYSRGASTTGSLELLNLTNPEMVERAHLDYLLAGARVIETNTYGANRLRLAEYGLA
EKVWDINLRGAKLARSAREVAGEPALVAGAVGPLRAARVGSPGKELSPGEVRALYREQME
ALLAGGVDLFVVETHADPKEAVEAIRAAREICRLPVVLEFAFWPVGPTEGVPAGPGRPGL
WEEDEDSGGLTTAAGYTPEGVAGYLNALPEGDRPEVIGLNCGGGVVHLLQALTRLKRELR
FEVLWCAMPNAGLPRYEGGRLYYAASPAYTASRVPALIEAGVKLIGGCCGTTPEHIQAMR
QALAGISSPAGLFPGTTHAAGRAATRGGTSAHLPAGASTHKEAPKTAPVETGALPGMGIG
APTFRAKLGRQFIISVELDPPRGSTARKYLEAAQALGRAGADVINVADSPMARVRMGAVA
AASLVQWQAGVETIVHFTARDRNLMAIQSDLLGAHAMGLRNVLALTGDPPSLGNVARATP
VYDVDSIGLIQVLAALNRGEDVAGNPIGRGTEFTIGCALSPNADDLAREVERFRRKVAAG
VHFAMTQPLYELAPLEHLLNELGGGPVPILLGVMPLHSFRHAEYLHNEVPGISIPERIRE
ELARAGDEGLKVGLEQAARLVTEARSLVAGIYVVLSFGKHEPVCDFVRWIRELVTKES
>A0A1G1FB96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium GWC2_57_13|TrEMBL
MKSGSNLEKVLASGKPAVTAELGPPMSADPHEVVHKAKQLKGFCDAANITDCQTAVVRIS
SIAAAAIAFQNGLEPVMQMTCRDRNRIAIQADLLGAAALGLKNCLCLAGDHQKFSAAGRL
KGHPGAKNVYDLDTSQLVSMLKKMRDESKQEGGDPIEVPPKFFIGASWTPMGDPIDIRPM
NLLKKVNAGADFIQTQGIYDMELFRAQMAKIRDLGLHERTAILAGIIVPKSAMMLKYMDS
SVAGVSVPKAMIDRMSKAKAAAGEDKKKMKELQEQEGIKITIELIHQALETPGVKGVHIQ
AIEWESAIEGIVKAAGLYPRPSF
>A0A7M1AZ80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp. B2|TrEMBL
MFEKLTDKLKNGKYLTLETTPGHNAQFSPTIDKIEELGLDKLVDGFSTTDNPLAKLKFNA
LFGAKLLQERFNKPVIATMSMRDRNKIALQSDLLGANEFDIRAILALTGDPATISDQPNT
KGVFEGDSTLLLDIISAFNSGMDYSGKPFNIEPQPIYPFAVVNSYAKNPKTLQKKMQKKI
KHGAIGIITQPVYDIENAKQLLELKEDANKECCSENKSAELIMGVFPITKLRTAQFLSAH
VPGINVPDCWIEKLRKASKGGSEEEYKVGFDLSKKLVDDLQELHPKIHLMTANQFQIAKE
LLT
>A0A7C7A230|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MQEFRSYIEAGEFVITAEIEPPKGSNLERTIEHAKSLAGKVHAVNITDSPMANMRMSPIA
VAHVVREETDLDAIFHLTCRDRNVIGLQSELLGAAALGVKTILILTGDHPERGDHPFAQG
VYEVDSLGLVEIADRLNQGYDCQGNKLAGSTQFYIGVAANPCARDLDMEIWRLTKKIERG
AQFVQTQPVYEMEVLYRFINKIKHLNVPVIAGILPLKSEKMAKHLEENVPGVHIPEWLVE
QLRERGRVAGVEAARGLLAMLPEVVQGAHIMPVGSRKIALEVIEGFHVTGASNVGLG
>A0A0B0KJA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. neg1|TrEMBL
MSLFSQCLEQKRFCILVEYLCSKRDTLAVTQSLAGFPAMMTLADRVHSDEDPAPLELAQR
YSFEIEKLLHFSGKGRDIKEFEHFLDQAEQQGYHNLLLLTGDKLKNHNFGREIPTQRSRY
LESVSAVMAAKQRHVFNIGVAFNPFKYTEAERDAQYLKLHKKIKAGADFLITQLGFDLDC
LQHSQSFISQNYKQFPLIACVMPLTLKRAQFMVKNQVAGLVIAPHIVDVLEREYAADPVQ
AEANVYARCALQILICKHLGYVGVHLSACHKPQEQQKLEQFLKQFENWSLEACEKAWKEL
WKMDSGLELKPELSTFSKPVSQIQILKYKKMHLMHHIFFASQAALGVGRFIFKANFWNKP
RPQHLLLKMEHWSKQQLVGCESCGHCRLDDTLYICPETCPKGLANGPCGGTTLDRCEFGD
RECIHSVKARLAKSIDQTEVLRSKLIPAISIETRYTSSWKNWFRNSDLN
>A0A7V9INV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MKVTEHIRTTTKTLFSIEILPPLKGRSIKSIYELIDPLMEFKPPFVDVTYHREEYIYKIR
DGGYLEKIAIRKRPGTVGICSAIINRYKTDAVPHIICGGFTCEETENALIELNYLGIDNV
LLLRGDPIKTETHFTPDPGGNNYALDLVKQVSSMNKGKFLDDDLKDVDPANFCIGVAGYP
EKHFEAPSMSTDLRYLKMKIEAGAEYIVTQMFFDNKKFFRFVENCREAGIDVPIIPGLKP
LTSKKQMTLLPKTFHIDIPDDLVKEIESCKTDDAVKEAGIEWCVHQSRELMKNKIPCLHY
YTMSNAGVIKKIASQVF
>A0A411YDH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Egibacter rhizosphaerae|TrEMBL
MSPETRRAIADLLENPRFEILPLKGAEAKVDALPAGTTVTVTSSPTKGLEATVELAQRLA
GRGLRVVPHLSAKQMPAGRLQEFAGRLLAVGVEDVFVVGGDATEPVGDFQNGWELLEALA
QLGHPFPNLGVPAYPEGHYLVDDRTLTDALLHKQEHATYMVTQLCFDADTIARWLGEVRD
AGVTLPAFAGIPGVVDARRLLSISVRLGIGDSVRFLRGNRESALRLIRGGYRPDRLVKRL
GTMARDGYVDLEGFHVYTFNQVAESYRWAVEAHERAEADRRRARRLRSPARRGRHTTAPP
RGRVDTRPAAMSDTADGTTADQQGFGPADGPGTPESPRHTTTTRAGGRR
>A0A1V6IZC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium ADurb.Bin018|TrEMBL
MTWPTIREILAARRQPTLSLEFYPPKDPLSFGILGGSIERMRPVRPDFVTCTYGAGGSSR
EFSFAAWELLARMGFQPVVAHLTCVGASRADLAAQVDRIHAAGIRNIMALRGDPPRGETE
FKPAPDGLAYAADLVALIKERHPDICCGVAGYPETHPEADSLVDDLRHLKTKVEAGADFI
TTQLFYDNAVYFQFVAAAREAGITVPILPGLMPVSSVAQLERSLAFSRATAPAALRTALA
AGSADDARAAGIAWLTEQIEGLVAGGVPGIHLYILNQARTILDPRLAECLARWRRLPTGA
TT
>A0A1C6JEY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Bacteroides sp|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYDTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNRYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQITMIPKTFKVDLPEELTCEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHF
YSIGAVDSIKEVAKLVY
>C6RBZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium tuberculostearicum SK141|TrEMBL
MSPRLSASAPLDYESEEESHVPERLALSFEVIPPRHDADAAKIDRLLEVLESYHPDYIAV
TSSQRSGWLEGTAAFIEKISHNTSMRPLAHLACTAGTRDELIGWINRLVDAGVRGLLALR
GDLPEGGMPEHYFQHADELVRLIRELESHQAARFAAGRLAVSVACYPSGHAESKNEDEDF
DVLLNKQRLGADFAITQLFFDAEDFLRFAQRAELAGVKIPLIPGIMPMTSLRRLERMGQL
SGLPVPERVRTRLAAAKTPEEEYEIGMELTAQLARTIVAGGAEGLHIYTHNNPDITQDLL
SRIGVSNDEH
>A0A1B3JJX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurellaceae bacterium NI1060|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMENLLWESIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATSEELKKIAQDYWDSGIRRIVALRGDEP
KGYDKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHIIT
QFFFDIDSYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPSWLTKAYDGL
DDDPTTRNLVAASVAMDMVKILSSEGVSDFHFYTLNRSELTYAICHMLGVRPSV
>A0A450YTM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. TC|TrEMBL
MHLSGSIPRVFSFEFFPPKTLKGRNTLRATWRRLSELDPDFFSVTFGAGGSTQAGTMETV
LEIQRDSSIDAAPHLSCIGSTCVKIRNILEHYLSNGIGRIVALRGDFPPDMVELGEFRHA
NELVAFIRAEVGDDPRIEVAAYPEFHPTALSASADLENFKRKVDAGANSAITQYFFNKDA
YLRFVDSCQRIGVHIPIVPGIMPITNYVSLAGFSERCGAEIPRWLNWRLQEFGDDMKSLR
EFGVDVVTELCQGLLDAGAPGLHFYVLNRAEPVMTIWKNLGLSETRGSR
>A0A1M7K487|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius pacificus|TrEMBL
MPETSLSVLSDRMIDGDISLELPPGSTDKFRPDTKVLPQGAKVFLPHLEGKPPERQITAA
KTLIEMGYTPVVHLGARHFETEADFTRHLDAHSVNGVTHALFLGGNPNRYTGPFGQALDL
LHHPSLPDSGIRTAFLGGYPEGHPDISENALDTALDAKIARCRDIAITPGIVTQFAFDGE
TMARFAQKMQARHPDVRVRLGLAGVTSLSRLIRYAIMCGVGPSLSVLRKSSGKMLGVLAD
KDPSDVTDTIERCMPGHGGQVDLHFFPFGGWKKTLDWVGSYRKLS
>A0A411YJM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Egibacter rhizosphaerae|TrEMBL
MSAEPVTRTRPDPKIGELLAAGPTYSIELFPPKTDQGRANLQGALEELTPFGLSFVSVTY
GAGGSTQDRTQTIVDDAVGAGYTTMPHLTCIGSSRAHLRGLLTGYHHKGRRNVLALHGDA
PKDNPELTDVGELKRAWELVELAREVADFSVGAAAHPEGHPAAPDRETDRKHQAAKLQLA
DFGVTQFFFRAEDYLAFIEDLSALGVETPIIPGIIPITDAKQVQKFAAMSGAEVPAELAT
RLDTVADDPDEVRRIGVDTATDLAKRLLDEGAPGLHLYALNRAQATSEVLRNLGLPREV
>A0A0K0GG81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzae (strain PXO99A)|TrEMBL
MPPHHHEKTARPVISIDMPSHTRAITDAYSLEVSVKDIGALTKAAPRLLPGSSMFIPYLP
GQHDAARLAAAQLVRSLGFEPMPHLSARRIGAPEELQAFVARLVDEAGVTRCFVIAGDPS
TPKGPFADSLSLIETGVFERSGIRTIGVAGHPEGHPIMRTAEQWDVLERKCRRIQERGMA
PLIVTQFGFDADMVVTWVEALRARGIPHPVRVGVPGPASVAVLARYAASCGVGACASVLS
NYGISIGKLFGNAGPDRFVDRLASRLTDAHGDIRLHVFPFGGIGQSVAWMAQYRSRASSQ
DRMSSVHADQA
>A0A351J5Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MEAEVDRLEAKIAAGAHFAQTQPVFDLRILEHWLMKVAGRVRIPILYGVMPLRNYEFAVH
LNNDVPGITVPEWAVERMRVRGPQAGMEMVREFISSASAASEISGIHIFPMNNAARILKV
VDIIDELGLRCQRKAKPIRIETRD
>A0A4Q1KGH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium fluviale|TrEMBL
MNAERRALEEARRILDTPLYADLGGDAEVSFEFFPPKTEKMEAQLWDSIETLTPLAPRFI
SVTYGAGGSTRERTHNTVARIARDTSIPAAAHLTCVDASKDEIAEVADAYWQAGVRHIVA
LRGDPPEMGAKFEPHPDGYASAAELVAGLRALHDFEISVAAYPETHPEALSAQSDLDNLK
RKLDAGAARAITQFFFSPEAYFRFVDKARAAGIEAEILPGIMPVTNFASTLRMAAMCNTE
VPSWMARLFEGLDDHPPARQLIAATITAELCRKLYAGGVRSFHFYTLNRAELSYAICHLL
GLRPQGQVA
>X7F6S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivivax isoporae LMG 25204|TrEMBL
MPRPEISLEFFPPKSLEASFRLWDTVQTLAPLGPRFVSVTYGAGGTTRELTRDAVKAIHN
HSGLRTAAHLTCVDATREETLEIARGFYDVGVRDIVALRGDPPKGQDTFVPTDGGFANSC
ELIEALKATRDFTIRVGAYPDKHPEAPSSQADVDYLKRKFDAGADEAITQFFFEAETFFR
FRDACDKAGIDKPIVPGIFPVENWKGARRFAEKCGTVIPAWVIEAFEAAERDGRSDLLAT
SLCSELCAELIAGGVDKLHFYTLNRPELTRDVCHAIGVTPETRLENVA
>A0A6C7CDW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 55:k:z39 str. 1315K|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDASGDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQARKFADMTNVRIPSWMSQMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A537KZ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrabacteria group bacterium ANGP1|TrEMBL
MSGASRPNGVRQGLAARRFVLTVEIATPRTREPFEQAIRPLLVLAREVRDDPRIDAVALT
DRSRSDQDHDPILTGHRVAEESGKMPIVHWAGKDRILRHLEADLQRAEALGLDTFLLVTG
DKVRQPPGGRPVRYLDSVNALAAARQRSQELLLAAAVSPFKYREEELVNQYLKAGKKIRA
GADFLMTQIGWDLRKYEEARRVLNERGYHAPLMAELLLLTPARSRRIRRVGLAGVTITGD
LAQRLEEEAASRDGGRGFAFRRLALQTASVRDLGYAGAQVSGLDTYPDIVRLLDEVERAT
RECPTPEARRQAWRELLTLQNGRAVQVAPAHGLYLKPGAMGERSGGARAREWARFRIMDV
IDHLLFKEGAAGARVLAPVLRRLDARSGVGRLLLRVEGAIKGPLVGCQTCGFCRLPETAY
VCPETCPKGLANGPCGGTKDNVCEFGDRECIHNQIYRVSKRAGLLAHLEETLIPPVPETA
WDSCSWVAHFRGEGPKVTRLPG
>A0A848UNC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ilumatobacter sp|TrEMBL
MTPSVSFEVFPPKESAGLVALGETVTQLAVARPSFVSVTYGAGGSDRQRSFDAIETVRRT
GVGVAAHLTCVGQSRAAVRSVIARFDALGVRHIVALRGDPPHGIDAPYEPHPDGFTDTAD
LVRAIKAERADTTVTVSAYPERHPQSPSFDHDLDVLAAKVDAGAERAMTQMFFDNASFLD
YRDRVRSRGIDVPIVPGIFPVHSFPAVARFAGRCGASIPTWFADRFAGLDDDRAGTAEVA
AELAAAQIAELAEHGVEHVHLYTLNRAELALAVCERLGLVERQPA
>W9FL62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces filamentosus NRRL 11379|TrEMBL
MALGTASTRTDHARTVRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGPWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A0D0BEJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Suillus luteus UH-Slu-Lm8-n1|TrEMBL
MKLSDKIAAYNSSRPFYTFEFFPPRTDQGFENLIPRISRLSTLNPLAISVTWGAGGSTRE
RSIDLAGLTQSDYGIDTILHLTCTNMVPGMVDDALRAAKVRGIQNILALRGDPSRGTEHW
TPVDSQFTCGIDLVKYIRSSPEFSSHFCIGVAAYPEGHPDRETDEDGSLNILKEKVDAGA
DFIVTQLFYDAEPFLEWIDKVRAKGITVPIIPGVMPIQTYSSFLRLIKLCGVKVPPTVMA
ALEPICHDDQLVKGYGVGLAVDIIRKITSTGKIKGIHFCTLNLEKSVQLVIEKLQWADGS
PTMKNRLIADAPGPMIHVQLANSSDLVIDPTTATNTATNALTFKQTLDPDPGRGELNNAA
TWDDFPNGRFGDYKSPAFGARDQWGGSGLCQYEGLSEWGHPKSTDDLTSLVLRYLHSEVS
SSPFSSLPLSPESLTILPHLEQLTKRGWWTVCSQPAVDGACSTDEIFGWGPRGGYVYQKG
FVEFFVEEQDLEKIEKKIEEEGQGWVHYFAGNLQGECRSNVPDDGRNAVTWGMFPGQEIT
QTTIIERESFLTWKDEAFSIWAEWASFYPPGSEERELLNSVRRERWLVSIVHHDYKRPDA
LWTFLLDGEFPV
>A0A316S9B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phascolarctobacterium sp|TrEMBL
MKISELLKSDKPCISCELFPPKAGSELQNALKIVDEIAVIKPHFISVTYGAGGTSAGQTV
AIAKSVEEHNIPALAHLTCIDATEAKIDGMLANFRANGIQNVLALRGDAVTNGVRDFAHA
SDLMRKISASGDFCIGGACYPEGHPEAGSLDKDIEHTKKKIDAGCEFLVAQMCFDNNIMY
NYMYRLLRNGIDVPVVAGIMPVTNAKQINRICELSGTKLPPHYRAIVERFADDPQALMQA
GIAYALGQIIDLIANGFKNIHVYTMNKPEILRGIMKNLSEIVK
>A0A8B9M1U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Accipiter nisus|TrEMBL
MGNTSIRELTMVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPILDADRHERLREK
MRRRQESGDKWFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETS
SMIIANTAVNYCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEE
VDGFNYAADLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRYLKEKVFAGADFIITQ
LFFRSETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIK
DNDAAIRNFGVEQAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWTEDPRRPLP
WAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYL
KSKSPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLK
EQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKV
LKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAF
ALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNTQTQ
Q
>K7W402|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabaena sp. 90|TrEMBL
MPDTHSFSAFNNFRKAALAGEFLITAEVAPPKGGDPVQMLAMAATLKGRVHAVNITDGSR
AVMRMSSLVASVILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDNPQAKAVFDLEAVRLLQLIRNMNQGFDFNEKPLTDGALDLFAGAAVDPQSQSWSGLQS
RFEKKIVAGAQFFQSQLITDFETLEKFMDKIAVGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEEGMKIAAEQVQIARGLCQGVHLMAVKREDLIAPILDLAGV
EKVS
>A0A7Y0GJR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp|TrEMBL
MNVPVSFEFFPPKTPDGVEKLRATRQALYRHQPEFCSVTFGAGGSTQEGTFQTVKEILGE
GVAAACHFSCVGATKSTVRQQLAVLQAMGVKRIVALRGDLPSGYGMGGEFHYASDLVAFI
RSETGAAFHIEVAAYPEIHPQSKSADADLKAFAAKVKAGANSAITQYFFNADAYFRFVDD
ASRLGADVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVI
TDLCVQLCTAGVPGIHFYTMNQAAATTEILRRLTPL
>A0A194RRI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Papilio machaon|TrEMBL
MTKAYLNDLLPWLQEKGICNLFIVLGDSFNPNRSDFKTSSEMISYIKAKTLDYFCIGVAG
FPYDDCKITALKEKIDLGADFVISQAFFEANIYKNYLEKCKDAKIDVPIIPGIFPFQSQK
ELDMFLKLCKVEVTDEFKMKLEGENVMDIIENLVLDLHNNLNVKHFHFFTINKLEITCDL
VKKIQLSL
>A0A0N1AHR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. AAP1|TrEMBL
MTRYDQLREARTALDTPLFAGLPGDIRVSFEFFPPKTDALMAQLWDVVQTLAPLQPEFVS
VTYGAGGSTRDRTHDTVARIIREARLPAAAHLTCVDASKAEIRAVAEGYWEAGVRHIVAL
RGDMGAPGVPFTPHPDGYANAAELVAGLKAIAPFDISVAAYPESHPDSPSQEADIDNLKR
KLDAGASRAISQFFFEPETFFRFQDKLAAAGIDAPVLPGILPVSNFAQTRKFAAACGAAL
PAWMESLFAGLDTHPASRQLVAATVSAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
RRPHGAAGLENAA
>A0A2R7QKQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. HMWF003|TrEMBL
MTAISFEFYPPKTDDQRAQLDRTAAKLKAFAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFDAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASELISFI
RAEHGDAFRIEVGAYPETHPQANDALLDLKHFKTKIDAGADAAITQYFFNADAYFHFVDA
VRALGVTVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDAESVRAFGAEVV
AGLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLKG
>A0A1G4W863|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium YSD2013|TrEMBL
MNISNLYKSKKTVYSMEVFPPKKSGAVETVYNTLYGLRGLPIDYISVTYGAGGTDSQKDK
TVEIASLIKSEYGIEPLSHLTCVGSTREQIAETLTHLKNAGVQNILALRGDMPAEGPCKM
AFPHASDLAQFIREQDSFFNVAGACYPEGHVDAESLDADIENLKRKVDAGVTHLTTQLFF
DNEVFYTFMDKVEKAGINVPIAAGIMPIIKKTQIERTVSMCGASIPAKFSRLISRYADSP
EALKSAGLSYTIDQITDLVASGVRGIHLYTMNNVEVARAVTTATESLFESVNKI
>F4H5A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547)|TrEMBL
MSAPTVSPAGTVPDEALGTRTVSRRATGPHVAAVDRPLAAVDRPTVSFELFPPRNPGAAP
RLWDTIQHLADAHPDFVSVTYGASGSTRQTTRALVRRLLRETSLNPIAHLTCVGTSRAEI
TAIVEEFLDEGARSFLALRGDPPAGQPDWQPHPDGLHTASELVELLREIESRRCAGSPSQ
AVRARVRPLSVAVAAFPRGNAATGGTRAQDVASLLAKQEAGADFAITQLFFDAEAYLGLV
AEARDAGVTIPIVPGIIPATDPARLLRVQDLSGVPVPRDLLDLLGSADDDVERHRRGVRY
GVDLVRGVLDGGAPGVHLYTFNQHHAALDLLEGAGLDGGARTGRQAAPDPTSPDPTHEGQ
TPR
>A0A3A5M8W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter cheniae|TrEMBL
MTSNEWAATPPSLSYELYPPATPKAAEAVLRTIDELSATNPDYVSVTFSGTPERRRASID
LIEHLVRNTRLRPLAHLTCVGETRESLELLVRQFLGLGVRGLLALRGDLPQDPDVARGDL
PFAHFLVELIRDIEGRHTATLAGGRLAVGVAAYPNRHPESPSFLHDIEVLVSKQRAGADF
AITQVYFDPTHYVRLVTAASAAGVTMPIIPGVMPMANVGRLERLAVMTGVRPDKALLHRL
ETASDGAERRRIGVQAAAVLAQAAFDGGAPGLHLYTFNDHRASVEVIEQLDLPAIRTLAD
VVPA
>A0A4Q8M6T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas winnipegensis|TrEMBL
MTPISFEFYPPKTDEQRAQLNRTAERLARYAPEYVSCTFGAGGSTLSYTAETVRHLKQHH
GFDAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHAGDLRYASELIAFI
RAEHGDAFQLEVGAYPETHPQASDALSDLKHFKAKVDAGADAAITQYFYNADAYFGFVEA
VRRLGVEIPIIPGIMPIANFAQLRRFSEQCGAEIPRWIAKRMAAYGDDAAAVKDFGADVV
AQLCQRLIDGGAPSLHFYTLNLAKPTQTVLQRLGIR
>M2ZJD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus ruber BKS 20-38|TrEMBL
MDRLRAPRGARIPFSVEFSPPRDADAEARLWRAVREFERLGPAFVSMTYGAGGSTRDRTV
RVTGELAEETTLLPVAHLTAVGHSVDELRAMVGAYADRGITNILALRGDPPGNPLGEWTR
HPQGLEYAEELVRLVRDLGDFHVGVASFPEAHHRSPDLEHDTRYLVHKLRAGAEYSITQM
FFDVEDYLRLRDRVVAYDPEQGAKPIIPEIMPITSLRTARRSLELSGSKLPATLEERLVR
AAGNGPEEDRAAVREVGIDVATEMAERLIAEGAPCLHFITLNFARATREVLARLGIAVPT
AV
>A0A1I7JWY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. INlla21|TrEMBL
MKIIDIIREKEVTLSFEVFPPKTDAGYAAVEEAAAEIAALKPDFMSVTYGAGGGTSKNTA
NISADLQNKYGVNVLSHLTCVSSTKEDVRSMISTYKEKGIENIMALRGDIPKEGRVCYDY
DHATQLIYDIKSVDDSLCIGGACYPEGHVECARQSEDIMHLKEKVEAGCDFLTTQMFFDN
STLYQFLYRIREKGIDVPVLPGIMPITNAKQVARSVALSGSTIPQKMKIMVDRFADNPEK
MKEAGIIYACDQIIDLISNGVSHIHVYSMNKPDIAAGMMRNLASIIR
>A0A5B7URA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. YIM 121038|TrEMBL
MLATGKTTYSFEFSAPKTPKGERNLWNSLRRVEAVAPSFVSVTYGAGGSTRAGTVKETQQ
IVADSTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLALRGDPPGDPMGEWGKHPEGL
TYAAELVQLIKESGDFCVGVAAFPAMHPRSTDWDSDVRHFVDKCRAGADYAITQMFFHPE
EYLRLRDRVAAAGCETPIIPEIMPVTNVRQLERLPQLSNADFPPALKERILSAQDDPAAV
RSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHQQA
>A0A4R1WVK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PP-F2F-G48|TrEMBL
MSGSPVDLLPGHSSRGRLEQVLRRGEFAVTAELNPPDSADPEEVYARAAVFEGWVDGINA
VDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQGDVLGAAAMGVANILCLTG
DGVQAGDQPGAKPVFDLDCMSLLETVRIMRDHAKFLSGRKLTAPPRVFLGAAINPFAPPY
DFRPYRLAKKIEAGAQFVQSQYCFDVPMFRAYMDKVRDLGLAEHCHILVGVGPMASARTA
RWIRSNVPGVHIPDAIIARLEGAADQKKEGKQICIDIINEVKEIKGVSGIHVMAYRQEEY
VAEIVHDSGVLKGRRPWRREQDPADAGVAERLDAARGGEMQDQESLAETAAKRPH
>A0A4Q9TAX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas winnipegensis|TrEMBL
MTPISFEFYPPKTDEQRAQLNRTAERLARYAPEYVSCTFGAGGSTLSYTAETVRHLKQHH
GFDAAPHLSCVGGSREEIRELLKLYRAIGCKRIVALRGDLPSGMGHAGDLRYASELIAFI
RAEHGDAFQLEVGAYPETHPQASDALSDLKHFKAKVDAGADAAITQYFYNADAYFGFVEA
VRRLGVEIPIIPGIMPIANFAQLRRFSEQCGAEIPRWIAKRMAAYGDDAAAVKDFGADVV
AQLCQRLIDGGAPSLHFYTLNLAKPTQTVLQRLGVR
>A0A0M8VYU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL WC-3723|TrEMBL
MDPALLDDFSLEMTGKDVPGLEEACDSVPSGTRINITFLAGEDTRTRLAAARAVKRLGFV
PVPHISARRLPSRPALEEFLAGLAADGTAGNVFVVGGDPARPEGPYEDALAVLRTGLLRR
HGVRHVGIAGYPEGHPGIADRALWSALTDKAAAIGAGRFTGDVITQFGFDVDPVLAWLEA
LRARGVHLPVRVGVPGPAGVRRLLRYAGRFGVGTSASVARKYGFSLTNLMGTAGPDRFLT
ALADRYDPARHGTVKVHFYTFGGLRATADWITRFRHESERSGEVRQTARS
>A0A1Q3R3R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium 68-10|TrEMBL
MSVNLSLEFFPPKTPEGADKLRAVRGQLYALKPEFCSVTFGAGGSTQEGTLDTVRAIVAE
GRPGVPHLSCIGQTADSIRQRLASYRAAGVRQLVALRGDLPSGYGMGGEFRHASDLVAFI
RAETGEHFRIAVAAYPEFHPQARSPEADLDAFATKVRAGVDLAITQYFFSAGAYFRFVDE
ARRRGVTVPIVPGIMPITNSTQLLRFSDSCGAEVPRWIRLRLQGFGDDAAAIKDFGADVV
AALCRRLHEGGAPGFHFYTLNQAAGVLQVCRRLGWAGDDI
>A0A4Q5WLM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSAPKVSFEFFPPKSPEMEQKLWDSVRRLEPLNPSYVSVTYGAGGSTRERTHDIVRKMAA
ETSLKPAGHITCVAATKPEIDQVLQDYWDAGVKRIVALRGDPTAGIGTKYAPHPGGYAYA
NDLIEGARKIADFDISVGCYPEVHPDAASLKSEIENLKRKFDAGAARAITQFFFFPDVYF
KFLDAARDAGITQPIVPGIMLQSNFKGLKRMADLCGTAIPARIANLYEGLDNDAETRDLV
TAHVAADLCNRLAEQGVDHFHFYTMNRAGLSLSTCRLLGIKPEIQS
>A0A6N3LSN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio nigripulchritudo SFn135|TrEMBL
MSYTHASHIDALNQNVAELSDDINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASRDELVNIANDYWNNGIESIVALRGD
IPPGGGAPDMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAINNVKVPGWMSKQFE
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQG
>A0A7C2JLB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MPAFHEREPFDPTLHEPPAPPPGHRSGSILERVLRRGEFAVTAELNPPDSADPRDVLAAA
EPLWDVADAINATDASGANCHMSSMGICSILSRCGVGAVLQISCRDRNRIAIQGDVLGAA
AMGVGNILCLTGDGVGVGDQPGARPVFDLDSPSLLRTLRTMRDEGAFLSGRKLATPPAIF
LGAAENPCVPPLEYRAERLAKKVRAGADFIQTNYIFEVEPFRRFMARVRDLGLDGKVYIL
AGVGPLASARAARWMRANVPGIRIPDAVIDRLERAARPGEEGKKLCIELIREIREIPGVH
GVHVMAFRREHLVGEIIEESGILK
>A0A853R815|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio ordalii FS-238|TrEMBL
MGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSAQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASRDELIQIADDYWHNGIQNIVALRGD
IPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQSDLVNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFN
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A7W5K5B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas campaniensis|TrEMBL
MSTQEHPLGVSFEFFPPNTDAGREKLLGVRDALAAREPRFFSVTYGAGGSTQDRTLETVR
RVRESGITTAPHLSCIGSEKGQLRELLARYREEGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSLERDLENFARKMKAGANLAITQYFFNADAYF
HFVERARALGVEAPIVPGIMPITNYAKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAF
GEEVISRLCQRLLDGGAPGLHFYTLNQAAPTLKILDNIVG
>A0A7Y8MDH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTPTVSFEFFPPKTDAMAETLWASIERLAPLRPAFVSVTYGAGGSTRERTHATVKRILDE
TALHPAAHLTCVSATRAEVDEVIRSYWQAGVRHIVALRGDPPEGIGSAYQPTPGGYANAA
ELARGIRAVGDFEISVGCYTEKHPESASIEADLDLLKAKIDAGATRAISQFFFEPAAFLR
FRDRARAAGIGVPIVPGIMPIANFKGLSRMAAGCGASIPAWLAERFAPLDDKPEIRSLVA
AVAAAELCEKLVAEGVPHLHFYTLNRAELAYAVCHMLGLREAVPARSVQ
>A0A259T2W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. XY044|TrEMBL
MKPDLRQAWDQQVLVGDGAMGTFLYQMGFPVGISYEELNLTSPEVIKDVHRRYVEAGAQL
IETNTFSANFDKLSKYGLESKVEDINRAGVRIAREVAGPTGYVVGAIGSIRGGKRTNVST
TELKKYFEQQIQALLQEGVDGILLETFYDVEEMYLALSIVRKLSPLPVICQFAVEDVART
LDGYTMPEAFRMMQQQGADVIGFNCRTGPNGIMSAMKTLGGHLSVPMSVYPNAGVADYVD
GEYQYGAKPDYFGQMAVKFADLGARIIGGCCGTTPAHIEAISSALQNYKPQPITYEPIAI
APAPIEIHEHLALGEGEGEGSKPNLVDLVKERHTVIVELDPPRDLDIAKFMKGAQALKDA
GADALTLADNSLAVTRMSNMALGHLVQAQTGLRPLVHIACRDRNLIGTQSHLMGFDALGI
DHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQTANFVVGAAF
NPHGKHLDKAVLRLERKIAAGADYIMTQPVYDPELIRALKEATSHLDIPIFLGIMPLASG
RNAEYLHNEVPGIQLSDEVRSRMSGLEGEEGRAMGVAIAKELLDVAMEHFNGIYLMTPFM
LYEMSAQLISHVWEKSGRQQPPLFHR
>A0A1C5LR67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Coprococcus sp|TrEMBL
MKLKEYIQTKRIIADGAFGTYYISLYGDGSRAENGAGLSNLPELANIKAPERVIGIHTEY
IEAGAQFVRTNTFASNTKSLSADMEKVKENICAAVMCAKMAAGKVDREIYLAGDIGPIPV
EGMLHSDRLTQEYIAIGETLLSQGIDILLFETFPELETILPAVTYLKENHDCTILVHFSV
NQFGYSNTGLSAKRLIAEANACPYIDGTGLNCGVGPGHMEKLIRKIAPDDTTFLSVFPNS
GYPKYLNNRLTFTDNAEYFTEKMEEIAALDVGIFGGCCGTTPEYIRRIAAGISADHPVRK
TETEAEKITVPEHPAYGFMERRVKEPAHKLIAVELVPPLNANDEKLLDAAHILKNAEVDV
VTFPDSPSGRTRADSVLMAEKIRLETGLCVMPHICCRDKNAIAIRSTILGASLNHITNFL
LLTGDPVPILFRQTTKSVFNFDSVGMMKIVQEMNSDTFTGHPVTYGGAINHNRMNTKAET
ERIRRKMAAGATFFMTQPIFSAEQADVIRQMKKETGATILVGLMPLVSRKNAVFMKNEMT
GIEIPDTVIERYREDMSREEGEACGVQIAREFMAMTDDFADGYYFSFPFNRVHMLKKILK
>N8TYB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 3789|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRAVHQDLQQLNPEFFSITYGAGGSTRERTLAAISDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDQDIQRFAEKVHAGANAAITQFFFNPDAYFYFI
ERIAKLGVHIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSKSIQEFGHE
VVVKLCERLIAGGAPSLHFYTMNHIQPNRQLVTDLGLA
>A0A6A7KUZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MANTPEVSFEFFPPQDVASEDRLWQVIESLAPLAPSFFSVTYGAGGSTRERTDRIVRRIH
TETTVSPAAHLTCVGASRDDVDRLARSWWEFGIRQIVALRGDAPKGQGPYAPHPDGYENA
AALVEGLRKIADFDISVAAYPECHPDSPSLEADIDNLKRKIDNGAKRAITQYFFENDGFL
RFRDRVAAAGIAVPLVPGILPVTNFARVLQFSQQCGTSVPARMAELFDGLDGDPETRNLI
AGTVAVEQCEGLSREGVEHFHFYTLNRAALTKAICWRLGVRPRAENAA
>A0A537RVV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTARQPASRLEALLRARQFAITAEITPPVSCEADDLLRKALPLAGLADAVNVTDGAGARA
HLSAPIAACLLARAGIEPVLQFTCRDRNRLALEADLMGAAACGVRNVLCLTGDDPRAGDQ
PQTKPVFDVDSVALTAIARELRDKGELPSGRKVAGHAAFFLGAADVPIDPPPSWRPDKLA
AKAAAGAEFAQTQFCMDTGVVRRYSAQLAKHAGTRDLFLLIGVAPLRSARSARWMRERLY
GTIIPEAFIERLERATDAAAEGERIAVELIEELAAIPGVAGVHLMAPANEDALPRVIVEA
RKRLPSR
>A0A4R8J6T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium litorale|TrEMBL
MATDLQCPKRMQFGPCGGVRPDGQCEMRTGPCVFPDVVPWTGVEPAPRPASAPLVLTDFS
CAPFDEADVAATAGILAHSCDAVLVGEHQNRPDFPPTLMGRLLLESGMSPWITLSCRDRN
RVVLEQELRGLRTLGVGTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGMVAAVP
ETPTAPPVRARPARLVEKQRAGASLAVLNHVPFPGTVADFMASARTAGLTIPVVAAVAVF
TDLVSAAVLQGLPGLELDQRVVEEVLGAADPVSAGIAAAVAEARALLAIDGVDGVNVSGL
ASASGTRVGAEIKAEVGRLIKAQEAA
>A0A537QVV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
AYPETHPSARSPGHDLDNLKAKLDAGASRAITQFFFDVDLYLRFRDRAAAAGIRVPIVPG
ILPVTNFAQLRRMAGGCGASIPDWMAGHFDGLDDDPDTRRLVAASLAAEQCRRLHANGVH
EFHFYTLNRADLIVAICHLLGVRAARPAAATA
>A0A3D3F736|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium|TrEMBL
VDRCRAEGITVPIVPGIKPIHLKNQLTVLPRIFRTDLPEELAKALRTCQSDDEAKQVGVE
WCTAQCKELIAGGVPGIHFYSLMASESVYKVAKEIY
>A0A1Q6R6Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phascolarctobacterium succinatutens|TrEMBL
MTSEKIIDILKNGKIHLSCELFPPKQGAELQNSLEIVNKIAASKPSYMSVTYGAGGSTVG
YSAALAKKVEDNGMPALAHLTCVKADEAKLAEVLGQLQGFGVKNILALRGDIPADMQGEE
IGSFAHASELMRFVKQQGDFCVGGAAYPEGHPESGSLEQDIENTKYKVDAGVDFLVTQMF
FDNTILYNYMFRLLRAGINVPVVPGIMPVTNAKQIIRICQLSGTKLPPQFRAMVEKFADK
PEALKQAGIAYATGQIIDLIANGFDNVHIYTMNKPEIFAGIMNNLGEIVDK
>A0A2D6WE25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSLTIDALSSAAANWSIEVTPNGASKVESFADALEPETHVNVTFLPGSDPADTNLVAKRL
HDEGMIPIPHIAARSIKDRKHLEKIVSTFAKQASVKEVLVIGGGVDKPIGEFDCSMQILK
TGILQANGITKIGVAGHPEGSPDIADNEIKRALQEKNEFAIKENLNMYIETQFCFEAKIV
LAWEKKAREDGNQLPIRIGIPGPATIKTLFRFAQISGIGPSMRFIAKQAGNVAKLMAVQS
PHLLLAGLAEGMAADKACLIKHFHYYPFGGFVRTAKYARAISDGNVSLKTNGGFEVIEN
>A0A537UDK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTEVTPPVSDGHRAPKTPTISFEFFPPKTEEMERSLWETIKRLAPLAPNFVSVTYGAGGS
TRERTHSTIARILAETELLPAAHLTCVGAARGEIDEIVGRYHDIGVRHIVALRGDPPGGI
GTAYTTHPDGYRNSAELVAGIKRQHGDIEISVSAYPEKHPESPDFDADIDFLKAKVDAGA
ARAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTSVPNWLAE
KFEGLDDDPETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A534MW68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MRAGSRLERILASGGFAVTAEIAPPASADASEIRRHAAAYRGMVDACNVTDGQRALVRIS
SLAGALIALQEGVEPIMQMVSRDRNRIGLQSDLLGASALGIHNVLCLWGDPPAAGNEKDA
KAVFDLNTEEMIATFRALRDTGILRGGDKVENAPKVFIGAAADPFRGSNEESFGKLRGKV
MAGADFVQTQGVYDVDAFEEWMRLVRKEWLHDKVYILAGVIPLKSAKMARFMVEKLGAVV
PKHIVNRMERAPNPKAEGVSIAVRTIKALEKIEGVRGVHLMPIGWEEVVPDLVQEAGLLP
RPDPTPRVTSPSA
>A0A534L941|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MRSGSRLERILASGAFAVTAEIAPPASADGAEIRENASRYRGAVDACNVTDCTRARVHIS
SLAAAAIAIQEGVEPVMQMVLRDRNRIALQADLLGAAALGVRNVLCLWGDPPSAGNERDA
KGVFDMKTEDMIEMFRNLRDAGTLRGGDKVKTPPKVFIGAAADPFRGSKEESFGKLRAKV
MAGADFVQTQGVYDVDAFEEWMRLVRKEWLHEKVYILAGVIPLKSAKMARFMVEKLGAVV
PTHIMDRMENAPNPKAEGLSIAVRTIKALKKVDGVRGVHLMPVGWDGVVPRLVKDAGLAP
RPETAV
>A0A534MLJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MAEAVGVRTVRSGSHLERMLASGIFAVTAEIAPPASADPTDIREIVSRYRGAVDACNVTD
CTRARVRLSSLAAATIALREGIEPVMQMVARDRNRIALQADLLGAAALGIRNVLCLWGDP
VSAGNEPEAKGVFDLKTEEMIETFRDLRDRGRLRGGDTVDAPPKVFIGAAADPFRGSKEE
SFAKLRAKVLAGADFVQTQAVYDIDAFEEWMRLVRKEWLHEKVYILAGVIPLRSAKMARF
LVETLGATVPKHIMDRMEKAPDPKAEGVSIAVRTVKALRKIDGIRGVHLMPVGRDRVVAR
VVKEAGLLPRPEPSF
>A0A534IVS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MRSGSRLERVLASGAFAVTAEIAPPASADATEIRQNAARYRGAVDACNVTDCTRARVQIS
SLAAAAIVLQEGVEPVMQMVVRDRNRIALQADLLGAAALGIRNVLCLWGDPPSAGNEREA
KGVFDLKTEEMIETVRNLRESGTLRGGDTVETPPRVFIGAAADPFRGSKEESFGKLRAKV
MAGADFVQTQGVYDVAAFEEWMRLVRKEWLHEKVYILAGVIPLKSLKMARFMEDKLGAVV
PKHIMDRMEKAPNPKAEGVSIAVRTIKALKKIEGVRGVHIMPVGWDGVVSKVLKDAGLAP
RPDLPG
>A0A414D449|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus gnavus|TrEMBL
MKIIDRLREDGIHISFEIFPPKTDAGYDKVIRAAEKMAGLKPEFISVTYGAGGGTSKNTA
KIASYIKHDLHVESLAHLTCASSTKDEVRSVIASLKEQGIENILALRGDISEDMVFPSED
RFHYAYQLVEEIRRHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSARQMKRSCELSGTVFPRRFQAILDRFGDSPK
AMEQAGIAYATDQIIDLLANGVKNIHIYSMNRPEVAAAIMHNISEIIQC
>A0A0N0YJD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL S-4|TrEMBL
MALGTPSTRTDHARTVRDVLATGETSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVRATEQIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPKGVRYAADLVRLIKEAGDFCVGVAAFPEMHPRSADWDSDIGHFVD
KCRAGADYAITQMFFHPESYLQMRDRVVAAGCETPVIPEVMPLTSVKQLERFAQLSNASL
PSTLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A0W1KK27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trueperella bernardiae|TrEMBL
MATCTSATPVLSAVPTPAARATDPTVTSPAANPPEPTANPASFGWLPARGSDQLPSHITT
SFEVMPPRNPQTAPKFWTTVKQLVDARPNFISVTYGAAGQDRRGARAVTEILARHVPTPP
IAHLTCVGTSIEEITQIVTDYLDSGVRTFLALRGDPPLGKPGWTPADDALVRATDLIRLI
REVD
>A0A1F3YMC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RBG_16_66_20|TrEMBL
MSSLENAAERLAAERPASVAAELVSGGSLEMGAHRPQDARDIAALLPAGTPVYVNHLPRH
RLLDTVPTLVAVREAGLEPVPHIAARRVRDRAELQTFLARAVGDAGVRKALIIGGDEPDA
AGPYADGAALIREGLLASAGLREIGLPGYPEGHPRIPRAVLERAIAEKMSLAAGQGLGTY
IVTQFSFSPARVIEYCAGLARAAPSVPVYVGLAGPTDPLALLRYAQRCGVSASLRALRAQ
GLDAVRLVTHTDPAEQLATLARYCASHADCNVVGIHLFTFGGVTAAAAWMNRYIASRGSS
A
>A0A0M8U410|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. H021|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMADWVAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A3D2SRT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter ursingii|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKIVHQELQLLNPEFFSIT
>A0A1B4XC33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuricaulis limicola|TrEMBL
MESQKKSSRNFSFEFFPPRNEDGRAKLRETVEQLAQLKPKFFSVTFGAGGSTREGTYETV
KSIQAMGQQAAPHISCIGTTRADIRALLDSYRKLGIRHLVTLRGDLPKDAPKTGGDFHYA
NELVSFIRAETGGEFYLEVAAYPEFHPESPSPESDIRHFADKVRAGANSAMTQYFYNVDA
YWRFVEEAAAQGVNVPIVPGIMPITNYKQLTRFSDACGAEIPRWIRRRLEGFGEDLDSIR
AFGLDVTTVLCDKLLEGGAPGLHFYTLNRAGPTCTVWERLGL
>A0A0D0UAI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus gattii CA1280|TrEMBL
MPHLTSLIATHNGPFHNYEFFPPLTDPGFVNLLDRIRRLTSPPFQAPLAVSVTWGAGGST
AERSLELAQQIVGMGVEVILHLTCTNMPKDKVDWALQRCKDLGISNILALRGDPPREEEY
AINPTSTPDFFKHADDLVRYIRQTHGDYFCIGVAGYPNPHPDSESEEEDFKWFKAKCDAG
ADFIVTQLFYDVDVFSEWVKTCRAKEINQPIIPGIMPIQNYASFRRLVNLTKCPVPDSIT
SDLQPISSDDAAVKRYGAELATKMVNQIIESGLVPGVHFCTLNLEKSVRTILDNLGWSAT
SKTSASDGVVKNKLIQDDSLVVNGIQINGKAGNTQNPAKDLSISPSEANQLAQLGLTSTT
LPPAPKTGLSAQGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKEWGVP
VSTSDLSALFTAYLHSDPNHLTTPFCDLPLSPESHMILPHLLALNSAKVQHWTVGSQPAV
DAAKSEDEVVGWGPRGGYVFQKAFVEFFVTEDEVNRLTKKVEEEGKGLITMYAANREGAF
RTNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWTEWSLLYPRNTPSRKL
LEGIANEWWLVSLIHHDYKDQDALWRFLLEDLQ
>J4J7X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter marplatensis|TrEMBL
MPLIHPSSPKLPGHITDAYSLEVSAKDIPALTAAAPRMLPGSTVSIPYLPGQDNDARLAA
ARAVRALGLVPMPHLSARRIASLAELESFVTRAVAEAGVERCFVIAGDPSTPLGPFADSS
SLIETGVFERAGIQVVGVGGHPEGHPVMSAADRWEVLERKCRSIGMRGMTPLIVTQFGFD
ADIVLAWLKTLRERGIEHPVRVGVPGPAGIAVLARYAALCGVSACASMWSKYGISLGKLF
GTAGPDVFVDRLAAGLTEEHGEVSLHFFPFGGIAQSVKWIAQYRAQGQ
>A0A831BHJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPSL
>A0A7V4G6Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans|TrEMBL
MSLKEKLEAHKFVILAEMEPPKGTELGDLAANAARVKGRVDAFLVPEMSNAVMRLSSLGG
ALFLQTRGLETVMQMCCRDRNRLALQGDLLAAAALGVANVMGVAG
>A0A285MZG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda parva|TrEMBL
MKVTDHIEKAKGETLFSFEIIPPVKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLFDKKLTRMRPGTLGICASITHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFAPTNGGHRFASDLVEQINDLNKGNYLHEVIETDNCANFCVGVAGYP
EKHMEAPSLKSDLKRLKQKVDLGADYVVTQMFFDNKKFFKFVDEARKMGINVPIIPGIKP
IAVKRHLQLLPQVFRVDIPEDLIDAVESCKNNKEVRQVGVEWCIEQSKELKEAGVPVLHY
YSMGKSDNIKAIAKKVF
>A0A7K2XB56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID2131|TrEMBL
MALGTASVRSDRARTVRDILASGGTSYSFEFYAPRTEKGEQSLWKAMRRVEAVGPSFVSV
TYGAGGTTRGGTVKATQKIASDSTLTPVAHLTAVGQSVAELRNILGQYADAGIRNMLALR
GDPPGDPLGEWIEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVVKAGCETPVIPEVMPVVNVKTLDRLPQLSNAAF
PARVKERILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A6M7TK61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium jarvisii|TrEMBL
MSARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A432UI88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfatator sp|TrEMBL
MEPRSHLHRVLREGHFAVTAEIGPPKSADGEVVRRKARLVKGYVDAANITDCQTAIVRMS
SIASAVLVMAEGVEPVIQMTCRDRNRIGMQADLLGAAALGVKNLLCITGDHQKFGNHPEA
KGVFDLDSIQLLDMVRRMRDEGKFLCGEELTGARPGFFLGAAANPFADPFEFRVKRLAKK
IAAGAEFIQTQIVYNVERFRRFMEMAREMGLTEKAYILAGITPPKSFGMARYMKYFVPGL
DVPDEILKRMKEAKDKREEGIRLAVEIIQQVREIPGVAGVHIMAIEWEEAVPEIVKRAGL
HPRPLEAEVRPPVVVEVEKPVERVEVIAPPKEEVPEEGPPKLEIPVEAVKEVFSTVRSSL
ESLREGVNLLYDSLMRLERALLGGEVVPAEAPEVPPPEVKPEEVAPPEEIKPEERPPEKE
EVKPEEKPPVEEKVEVKEEKPPEKEKAVVEERPPVEEKPPVEEKPPVEEKPPVEEVPPVA
PPEGVEILGFFGEYRDLSERAAGLPEELYKDPGTAYIREVEIGKGEKAFRVGGTNVLPFH
LFEGEMRQVPRIAMEVLDVKPEGWPESLTKYFADVLGDPGAWAKKCVEVYGAEAICVYLM
GTDPNYLDLDAKHAREVVEKVAQAVDVPLIIWGAGHAEKDVEVLREVVELVGDRGTVIGP
VVEANHRTLGATAMGYGVPVVASSPIDVNLAKQLNILLENVGVALDKILMDPSIGALGYG
LEYTYSVMERIRLAALYAQDDKLQVPFICNVGREVWKTKEAGLPSDETLGDQEVRGVLME
AITSVALALAGGDLFIMRHPKAIELTKTIISGLMQ
>A0A852LUV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Centropus bengalensis|TrEMBL
MVNETQHTCSTSSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDVCVAGYPKGHPEAESYEADLRHLKDKVFAGADFIITQLFFRAETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRSYG
VELAVSMCRDLLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A8J7FLA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plectonema cf. radiosum LEGE 06105|TrEMBL
MLGTLNSTQLTTFRTSANHGEFLITAEVAPPKGGNPQHMVEMAATLKGRVHAVNITDGSR
AVLRMSSLAASVILQQQGIEPICQMACRDRNRIGLQSDLMGAHALGIRNILALTGDPVKA
GDHPDAKSVFDLESVRLLQLIGKLNNGLDSNDKPLTDGATDLFVGAAVDPQCRSWSGLQK
RFERKLAAGAQFFQSQMITDFEILDKFMTQIAAGCNKPILAGIFLLKSAKNARFINKCVP
GVEIPGHIIDRLEQAKNPLEEGMKIAAEQVQIAQQLCQGVHMMAVKREDLIVPILDMAGV
KAVKI
>A0A4Q7QQH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2569|TrEMBL
MFELICEVEPPTRPDLKKVRHQIGVMSPIADGFLIPDNHIGRATVSSVAVANEVQLMGAR
GIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVHGDDPAEGARTSQLTVRRMIEQTRETT
YPGCDPFKVGAATRLRPVPKWKAEADFLYVQVSYDLDELLRWRESVELDIPVYAGVMVLA
SAQMAHNLAKLPQLKIPAELIDAVERDRDAGVDHACEQILKIRDSGAFEGVHLIPVSRYR
QVAARLERDLLERDL
>A0A124IL65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibacter sp. BRH_c52|TrEMBL
MKVTDHIKQAKGKTLFSFEIVPPQKGQNIQELYDNINPLMEFKPPFIDVTTSREEHLYIS
KENGLLEQKITRMRPGTVGICASLKYKYNVDAIPHVLCGGFTKEETEYLLVDCHYLGLDN
VMALRGDAMKHEKYFAQTKGGHQYARELVSQISDLNKGKYLHEIEETLYKPDFCIGVAGY
PEKHMESPSLDADLRRLKEKIDAGADYVVTQMFFDNQKFFEFVDKARAMGITVPIIPGIK
PIAIKRHLQVLPQVFKLDLPEALISEIEKCTNNEQVRQAGIEWSIAQSKELVAKGVPVVH
FYSMGKSDNIKAIAKEVF
>A0A0Q4GGS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. Leaf216|TrEMBL
MKITDHIKNAKGKTLFSFELLPPVKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QANGLLQKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHCYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMSTDFKFLKKKVEAGAEFIVTQMFFDNQKYFDFVKKCREHDINVPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNNEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKKIAKAIF
>F0XGD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grosmannia clavigera (strain kw1407 / UAMH 11150)|TrEMBL
MHIRDMVAEAERSKQPSFSFEYFPPKTAQGVQNLYERMERMHLFGPKFIDITWGAGGRIA
ELTTEMVAQAQTYFGLETCMHLTCTDMGEDGINDALRRAYQAGCTNILALRGDPPRDADS
DGWVAADSKFRYAKDLVAHIQRHYGDHFDIGVAGYPEGSDDNSNEDELLEHLKQKVDAGA
SFIVTQMFYDADNFLRWLARVRAAGITVPVLPGIMPIATYASFWRRVNHMGCRVPADWLA
ALEPVKNNDDAVREIGKTLVAGLCRAILAGGDIVHLHFYTMNLAQATRMVLDDLGWLPSA
DRPRPPPALPWRQSLALGRRDEDVRPIFWRHRGKSYVARTADWDEFPNGRWGDSRSPAFG
DLGSAYGAGLPGSSAQNRARWGAPRCIADVAALFVRYLLGDLASLPWSDSPLTGEADLIQ
PDLVALNRRGLLTVNSQPAVDGVPSSDPVHGWGPPNGFVYQKSYLELLVPPALYPALADR
VRAHPHLTFHAGSRHGPLETNAPADGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQ
LGAEWARCYDVGSPSRALISQMMDEWHLVTIVNNNFHQPRTIFTVLDGLALPDIDKEVEG
TADTTASAVKVNGAATVAI
>A0A2E1XV61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacteriaceae bacterium|TrEMBL
MASPRFTRTPHADQPLSVSFEFFPPRNEAMAQRLWETVQRLAPLQPEFVSVTYGAGGSTR
ERSLDAVRRIIAETSLNVAAHLTCVDATRQEVDAVIGEFVASGVRRFVALRGDPAAGVGA
QFQPHPDGYVNGADLVKALHAKGDFEVYVSAYPEKHPESPDFATDIEMLKRKVDNGATKA
ITQFFFDNDNYERYVERARRAGIYIPIVPGILPVHAFTQVANFAGRCGASIPQWLADRFE
GLEHDPHTHQLVAAAVAAEQVLDLMERGVDDFHFYTMNKPDLVFAICHLIGIRSRTPGQP
GAKAA
>A0A5B9ABH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVRGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPWFINSV
AFVKITQ
>A0A2Z4PCY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus mutanolyticus|TrEMBL
MTTPAISFEFFPPKTLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETMQIVADYAAAGVHEIVALRGDAPQGQDRFAPHPQGFANSV
ELIEAIAARGDMTIRCGAYPEPHPESPDTAADVAWLKRKTDAGATSAITQFFFDAETFFR
FRDQCERAGITARIIPGILPIQSWAGTRRFAERCGTSVPAWAEDAFAAAGKAGEAQLALE
TCVQLCSDLVAGGVDSLHFYTLNKPDLVQKVCAALGVVPPRGAMSDVA
>A0A1H4X9R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beijerinckia sp. 28-YEA-48|TrEMBL
MSTAPVAAKPPDPIDATVDQIAAFMRDCSFEATRPSAGDVAALGKTLAPGTQVYLTMLPH
RPLDEMMAAAVAIRQAGLEPVPHLSARHFPRFDVLERHVGRMVDEAGVRTALLIGGDAEH
GVGEIQTALSVIENGLFQRRGLKAIGLPGFPDGHPAMGEDEIEANLVTKLAAAQQAGLEP
HIVTQFCFDSRSIIAWLHWLRQRGVHAPVRVGLAGPTSLMTWLNYARKCGVKASAEALAS
RSGLVRHAFKAVSPDPIIRTIAAAVAAKQIDGVTPHLFAFGGIGATAKWVQPAISGAIRL
NKDGGFDPA
>A0A1T5K0Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium WCE2008|TrEMBL
MNITEILESSARPFPSIEIVPPLNGISKDELLNTVGQFMDFDLKYINVTCHRDEFEFRQH
ADGSFSRHLVRNRISPVAVCGAIMSRYKVEMVPHIICGGNSPEEIESLLYDFNFLGIGNV
MALRGDSITGEKRFTPTPGGYNHADELVSAIRRFDGKNGSHFCIGVGGYPEKHFEAANLE
TDIANLKKKVDAGADYIITQMFFDNEVFYSFVDKCRKAGIMVPIIPGLKPLSTARQVAAL
PEAFSLDIPLELTEAISKASGPEDVYRIGTEWCIRQTKDLLRHEVQAVHYYTMGKSRNIV
EILKACF
>A0A3N4KR20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morchella conica CCBAS932|TrEMBL
MLKITDKVAALRPGEPFHSLEFFPPKTTMGFDNLEARLRRMACALRPLFVNVTWGAGGST
ATKSLQLAELCQRQLELTTCLHLTCTNMSQAVIDETLEAAKEIGIRNILALRGDPPRNEE
YSNAPSDATANGTSGIEFEYAVDLVKYIREKHGDYFCIGVAAYPEGHVEGACPERQDVEF
DIPFLVEKVKAGADFIMTQLFYDVDKYLSFEKSLRDEPSGVFRDLPIIPGMMPIQSFQML
KRITKLSGASIPPDILTRLEDVKGDDEGVKREGVNIVSEIIEKIKSTESTQLRGFHFYTL
NLEKAVSFILERTNLIPAPEESVFEEIDGPITNGNNRRDRRSSSVTSDPHNRVIIDSDSG
ITESYGHAFASEAGFLKPPEQNRPPEVALAISEGEGSLGREATWDDYPNGRFGNARSPAF
GEIDGYGPSLHLSQAQAVKLWSYPVTTDDISALFVKHIRGELEAIPWSEQELSSESKVIQ
EHLIKLNTKGRWTVASQPAVNAAKSTDELFGWGPKGGFVFQKAFVEFFCSPDDWTALKEK
LDKLEEMSYYAANKNGDYQSNVPTGEDSLHAVTWGVFPGKEIITPTIIEEVSFKAWKDEA
FSIWNEWGRVYPSRTASSKLISEITKTYYLVNIIHHGYLEPDFLWEFLEA
>A0A2M7EAM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium (Candidatus Ratteibacteria) CG01_land_8_20_14_3_00_40_19|TrEMBL
MSKLSEALEGKKFVVTSEIGPPKGTNIEKCLEDAELLRDKVSAINVTDIQSAVMRIGSLA
ICHLLAEKGLEPVFQMVCRDRNRLALQSDLLSAWVLGIKNVLCLTGDYTSLGDHPETKPV
FDLDSVQLLKTVATLNQGHDIAGHELDGTPNFFAGAVVTPGCDPLEPQIIKMKKKIDAGA
KFFQTQSVFEPKKFESFMNDVEKFHVPVMAGIVVLKSAGMAKFMNENVAGVFVPEEIVKE
MAETKKEDRRKKAVEIAARIIREIKPICQGAHIMPLGWDALVPEI
>A0A6C9SQL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGI
>A0A2M8PMP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phototrophicales bacterium|TrEMBL
MKVIEHLAKAKKPLVSFEIIPPKRGGDIKSLMKIIDDIAQFNPPFIDITSHAAEVIYEET
PTGIQRRIKRKRPGTLGICALIQNKYNIDAVPHLLCLGFTREETEDMLIELQYLDIDNVL
AVRGDDSGYRKPLEYGRTANK
>A0A8I0Z3H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRKETADHFHLEVAAYPEMHPQARNFETDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A2M8NFW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phototrophicales bacterium|TrEMBL
DQAGNPIGGATAFTVGCALNMGAADIDKEIDVLLKKIDAGADFALGQPIFEPRLAEQFLR
RYEQITGTALALPVIMGVMPLHSLRHAQFLHNEIPGISIPDALMKRVADAGDNAPDEGII
IAQELMTDLRGMVQGAYIIPSFGKYDLAARLIREVALI
>A0A518HM90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stieleria neptunia|TrEMBL
MGVRFSTTSHSDLRSQMSSPIKLADHFNGEQCAISFELFPPKTDAGMDLLEKNVERLKAF
QPSFFTCTYGAGGSTQSRTLDVVQRVREMTGLPVASHLTCVGSTVEQLREYLAEAKRRGA
DYIVALRGDPPKGSESFQAVEGGLRYANELVELIQASFPDQFGIAVAGYPEIHQEAPDAQ
TDLDNLKRKVDAGADVIVTQLFYDNDDFYRFRDACQTAGISIPIVPGILPVTNFKQALRI
AGMCKARIPDQMAAAMNENDDADYQFKVGVDHARVQTIDLIENGVPGIHYYVLNKSDAAG
QMLDGLSLGVQS
>A0A1Z9T828|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pelagibacter sp. TMED273|TrEMBL
MKVTDHINKSNDTQFSYEIIPPLRGKGIKIVLDMVESLQKFNPPFIDVTSHASTVSLNKD
GKKIKKKKRPGTISICGIIQNRFNIDTVAHLGCNGFTKEETEDALIELGFLGIENILAIS
GDGNPKEVLNDGKTINANSLDLVHQINDLKDGKYLTDISNSSPIEMCTGIGVYPENHFHS
NNFEQEISLIKRKIEAGADYAVTQMFFDNKKYFDFVDKCRAQGITIPIIPGIKILDKPRQ
VESLERIFHINLPEELKNEARENIEHIDEIGTKWAINQSEELINAGVPVIHYYLMNDTSC
MLDILNYLHK
>A0A6B3ET52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID11233|TrEMBL
MAFGTPSTRTDRARTVREMLATGKTLHSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSV
TYGAGGSTRAGTVKATQDIAAESTLTPVAHLTAVNHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGPWVEHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPQDYLRMRDRVVAAGCETPVIPEVMPLTSVRQLERFAQLSNATL
PTALKERILAAKDDPAAVRSIGIDFATRFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>C2M1V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga gingivalis|TrEMBL
MKVTEHIAKAQGKTLFSFEIVPPKKGNSIEELYKNIEPLLEFKPPFIDVTTSREEFYYKE
HPNGLLEKKLVRMRPGTVGICSAIQHKYNVDTVPHVLCGGFTREETEDLLVDCFYLGIDN
IMALRGDAMKEEKYFRPTKNGNVYALDLVKQINDLRKGIYLHDTLENNTGMDFCIGVAGY
PEKHIEAPSKAFDLEKLKEKVDNGADYVVTQMFFDNKQYFDFVEKARQMGINVPIIPGIK
PISVKRHLNIIPQAFFLDFPEELVKEIEKCKNNNEVKQVGIEWAIAQSKELRQAGVPSLH
YYSMGKSENIIQIISKVF
>A0A352MNK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDASRNELRAIAQDYWNNGIRHIVALRGD
LPPNGGKPEMYAADLV
>A0A3N1UHW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosoma caldarium|TrEMBL
MKAGSNLEKVFTQGHFAVTGELGPPRGASVEVIEKKAGYLRGVVDSINVTDNQTSVVRMS
SVAVCKLLVDMGLEPNLQMVCRDRNRIAMQSDLLGAYALGIRNVLCLSGDHNRFGDHPQS
KNVYDVDSMQLIGIVKKLRDEGKMLSGQELEGVPKFFIGAAANPFGDPFEFRVTRLAKKI
DAGADFIQTQCIYNMEKFRKYMHIAHEEGLTEKCYIMAGITPLKSVGMARYMAKFVPGLD
VPDYYIDRLKGVEKKKQADEGIKIAVEQIQEVREIPGVRGIHLMAIEWEHKVPEILEAAG
LLPRPSVN
>A0A0T2N1B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp. Root635|TrEMBL
MLDDNLRASRQTAHERPELQISFEFFPPKTDVMEEKFWDTVHKLAPLKPRFVSVTYGAGG
STRERTLRMVRRIKAETGVDAAAHLTCVGATRDEVDAVVRGYQQAGINRIVALRGDPPEG
VGQPFVPHPEGYQNAADLVGGLRRIGNFDISVAAYPEKHPQSADWRSEIDNLKRKLDAGA
DRAITQMFFSNPDYLRYLERARAAGITAPIVPGIQPIHSFKQIASFAARCGTAIPAWLAE
RFDGLDEDPETHALVAAAVAAEQVTELVDEGVTEFHIYTHNRSPLALALGRILGRRHEAE
AVNAA
>A0A150A8F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. LB1|TrEMBL
MTNLSNETGVRHRSSNAADLVRNMSYEVMPFKNTEQDVVDHVPKTVPLTVTVTEAKGIDT
TLNLTERLINHGYQVSPHLPGRQFVDDAHVADVIARLSEIGVKSVFVIGGDAPNPAGKFV
DAFGLLRAMEEVGHPFQEVGIGGYPEGHGAIEQELIDLALQQKAPLATRILTQICFDATT
TSKWAAGVAASGVDRPIYIGMPGPVSRQKLMRISAGIGLGQSARFLQKQQSMLWRFLLPG
GYNPTRLVKQLGGAVPKTSNNIAGLHIFTFNELRKTEIWRQKLLTAIVEKDARS
>A0A093QF08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Manacus vitellinus|TrEMBL
MVNETQQSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEGGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAADL
VKHIRSEFDDYFDICVAGYPKGHPEAESYETDLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGHRVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A2H3ILF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium sp. 'occitanis'|TrEMBL
MHVGQKLQEQAATGRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRS
ELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALEAAYNAGCTNILALRGDPPREQEK
WEAAEGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNSDVDQLIDHLKEKVDAGSTF
IVTQMFYDVDNFLNWVDKCRAKGINAAIIPGIMPISTYDAFMRRSNWTKIRIPPDWLEKL
EPVKADDAKVREIGSKLVAEMCRKLLASRQIHHLHFYTMNLAQATRLILEELKLLPSEEA
PLHKPLPWRRSLGLRRRSEDVRPIFWRNRNASYIARTADWDEYPNGRWTDARSPAFGELN
AYGVRLKGTNEQNIKLWGAPKSIKDLSDIFLRYLNGKLERLPWSDSSVTPETSDIHNELV
DLNKRGFLTINSQPAVNGVKSTDPVHGWGPRNGFVYQKAYLELLVPPEHVDELLRRIEKN
PDLTYYCVNKTGELKARSDEGPNAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQLGDDW
AKCHPADSPSRKLLQRVMDEWYILNIVNNDFHKKDDIFRLFDGLVIKDFETEVTGTAPVV
ANGTN
>A0A3M8T3U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLQLPR
>A0A1S2VYK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. suis|TrEMBL
MHSPMFTLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPGLKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRAAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNAEPLFLGTQG
>A0A126RZ43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYQAAGIRRIVALRGDLPSGMGMASGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTVSIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A076PR79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas testosteroni TK102|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A7L0ETR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trogon melanurus|TrEMBL
MVNESQPSSTSSSSRSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETVLHMTCCNQSRDDITGHLQKAKRLGLKNVMALRGDPIGEEWEEEVDGFNHAVDLV
KHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFVITQLFFRSETFLKF
LRDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRSYGV
ELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGLWREDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYISGEPNRNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6H1WTR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosulfurimonas marina|TrEMBL
MSRFAEILQKKDFVITFELVPGRSTRTRHFRDIMRFAEEVAGEGLFDALSITDNAGGHPA
LAPEALGRELKRLGHEPIIHFSCKDKNRNVIESDLLALDREGLRTLLVITGDYPRYGYRG
RAKPVFDLDSVQLLRLISEMRRGYRLPPEVPGGGVTLPPVPLFPGCVVNPFKWTEAETLL
QYWKLLKKIRAGAAFAITQVGFSARKYQELLFFLKEEGQADFPVLAGILVMDRRLARILY
RGAVPGITVPEGLYRRLQGLSEEEARAEALERAARLMAVCRGLGYRGVHLCGAPLELEAA
RRLLSLYEEYRPRWREFLSEFAGAPEKAFFLYPRDPESGLNLPERRPLSPARRRSPVYLL
SRAAHGLFFARKGPLVRPLRALAHRISGSRGEHLFTRLEYWIKKVLFECQECGDCTLPRL
AFLCPQSQCAKYLLNGPCGGSRDRWCEVYPGLRRCVYVRAYERLSPEERRKVFLEEELPP
RNWSLFRTSSWLNFYLGRSAISLSEE
>A0A7Y0JN26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes sp. TBRC 11911|TrEMBL
MALGLPSRLPGTPAIGDMVRGAMPTFSFEFFPPKTPAGETNLWQAIRELEPLRPSFVSVT
YGAGGTTRDTTVSVTERVATETTLLPMAHLTAVNHSVAELRNMVGRLAGAGIRNVLVVRG
DPPGDPMGDWVPHPEGVLYAEELVRLVKEAGDFSVGVAAFPHKHPRSPDVESDTANFVRK
CQAGADFAITQMFFDADEYLRLRDRVSAAGCDVPILPGVMPVTRMATIARSSQLSGAPFP
PKLLERFERIAGDEAAVRALGIEMCAGMSARLLAEGAPGIHFITLNRSTATREVWQLLAP
SDVAVPAR
>A0A6G3C4R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5643|TrEMBL
MALGTASIRSDHARTVRDMLADGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSLDWDTDVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLERIGSLTNAAF
PAALKERILTAQDDPAAVRSIGIEFATEFCAQLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSSQA
>A0A0P6WR79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. SG61-1L|TrEMBL
MSYAAIHPDWEKSRANMVDGYSLEMTAKEIEGLKEAASKIRPGTQIAVTFLPGEEMSQRV
ECAKLVRDLGFEPIVHLSARRFTSEAELEQYLSDITSQAAVKRVFIIAGDPPEPEGPYSD
SLQIIETGLLEKYGIEIVGIGGHPEGHPNVSKPDLWIWMEKKIEAIRSRGMTPLVVTQFA
FDDDAIVEWVKEMRGRGIDVPVRLGIPGPAGIKRLLGFAKRCGVGASASVMKKYGISLTN
LIGSAGPDKLVNSLDKGLTEEAGRVRLHFYPFGALTASADWINGYADKH
>A0A1E7XBA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus sunkii|TrEMBL
MSLTELFKTKTVFSLEVFPPKKSSPTEAILPTLKRLQSIHPDFISVTLGAGGTDHCNGTV
EIANLIQNQLDIPAVSHVPGLYQSKEDVLALLDRLDNINVKNILALRGDRIPGKEPVGDF
NHANELVAFVHEQRPDFSIASACYPNCHTEAPDFVNDITHLKEKVDAGADHLISQLFFDN
QAFYDFKEKTELAGIHVPIEAGIMPCTNKNQIERITQISGVPIPKKFAAIMDRYQNSEEA
MLDAGIAFAVDQIIDLVSQGVDGIHLYTMNKSKIAKRIWNETRSVFEAADTSIQKDHA
>C0C3T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] hylemonae DSM 15053|TrEMBL
MKIKDILRDEEPHISFEVFPPKTDAGYESVLSATEKIAALKPSFISVTYGAGGGTSKNTV
NIASHIQNDLGVVSLAHLTCASSTKEEVHQVIEKLKEKGIENVLGLRGDIPDDVQFPVSN
QYKYAFELIRDIKSQGDFCVGAACYPEGHVETEHKKDDIENLKNKVECGVDFLTTQMFFD
NNILYNFLYRIREKGITVPVLPGIMPVTNSKQMKRICSLSGTALPERFRAIVDRFGDDPK
AMQQAGIAYATDQIIDLIANGINNIHIYSMNKPEVAGAIMKNLSDIVKV
>A0A261V668|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella genomosp. 2|TrEMBL
MTSTPALSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRMLQ
NLGCDAAPHLSCIGATRDNLREILAAYREQGVRRLVALRGDLPSGMGGDAGELRYAADLV
AFIRQETGDAFHIEVAAYPEMHPQAASPAADLAHFVAKVDAGADAAITQYFFNADAYFDF
VDRAQAKGVSIPIVPGIMPITNHSQLVRFSEMCGAEIPRWIRLRLAEFGDDKASIRAFGV
DVMADLCQNLLDNGAPGLHFYTLNHAEATLGIWRQLDLASAGVA
>A0A1W9YZ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium bacteremicum|TrEMBL
MDYGPCGGVRPDGACEMRPGPCAFPEVVPWDDAAAAESTLRAPRVLTDFSCTPFDHADVR
ATAGILAAGCDAVLVGEHQNKPDFPPTQMGSLLLECGVSPWITLSCRDRNRVVLEQELRG
LGSLGIRTVFCVTGDGRGYDVRPEVTQTFDLDGPRLVALAAGLGMTPGVPETPTAPPISG
RPVRLVHKQRAGAQLAVLNHVPYPATIAEFMAAARAAGLTIPVIAAVAVFTDHVSAAVLQ
GLPGLELDPEVTESVLAAADPIEAGIDAAVAEARALLAIEGVDGVNISGLASAAGPRQGA
EIKAEVGRRMREVIR
>A0A1S7SXJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium fabacearum CFBP 5771|TrEMBL
MLRSETARHNGEIRGDIRLSFEFFPPKNPEMENQLWETVAELKKWDPDFVSVTYGAGGST
KAPTLDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIG
TDYRPHPQGYENAAALVKGLRDISDFEVSVSAYPEKHPESASDAVDIDMLKRKADNGATR
ALTQFFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPSFLDERF
AGYDDDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSA
A
>A0A4D6XPM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MSFLKNEYHQDIVNQKLSNLNKLIRCSFEFFPPKNIYLEEKLFSSVIQLNKLKPFFFSVT
YGANSGERKKTYTIVKKIYEKTGVITAPHLTCVDATPSELEKIAKFYWENGIRSIFALRG
DSDNTNHLHQMYAYDLVVLLKKIADFDISVAAYPEIHPEAKNAQSDILSLKKKVDAGANR
AITQFFFNTESYLRFRDNCIKNNINVEIIPGILPIYNFSQLKQFSKLTNVHIPSWMFEIF
NRLTNDLITQRIIGASIVIDIIKNLSKEGVKNFHFYTLNQSDVVYSICRLFGF
>A0A7Y6GEA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CAI-85|TrEMBL
MTGKDVAHLEAAREAVPPGTRVNVAFLGTETQELRLAAVRAAARLGFVPVPHLSARRLRS
RAELAEFLAALREAGATERVFVVGGDPAVPRGPFPDTLSVLRSGLLQEYGVRHVGVSGYP
EGHPAIDGPVLWSAIEEKAAVLREQGLDGSVITQFGFDVEPVLTWVEELRSRGVDLPVRV
GVPGPAGVRRLLSYATRFGVGTGAGIARKYGFSLTNLMGTAGPDRFVQDLAEGYDPVRHG
DLGLHFYTFGGLAATADWVAARA
>A0A8B9CM87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anser brachyrhynchus|TrEMBL
RELTMVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQD
SGDRWFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIAN
TAVNYCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNY
AVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSE
TFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAI
RNYGIELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAH
PKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPR
EELLKMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKV
NRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYES
RVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQ
WAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPAQ
>A0A7H2BJV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia amarae|TrEMBL
MAPHTALSYELYPPRSVESRDSLLQTIDELSATSPDYVSVTYSGTAERKQQTLALLDYLV
HETKLTPLAHLTCVGHSVGELEHAVRLIVGLGVRGLLALRGDIPAGVSPDALELPFARYL
VELIRRVEREDFAHFAGGKLSIGVAAYPQKHPESVSLLQDIEILLAKQRAGADFAITQVY
FDNARFQGLLDAAQTAGVNLPIIPGIMPVTSLRRLIRLCELAGLAIPLDLASALENADNK
AERHKIGVEYALHQCKAALDSGASGLHFYTFNEHRAVLDVLEHLDIAPYTSRYFSPLKSS
QPSHFSTSDAEYASVSASA
>A0A0N0CT92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MPLQYSFEITPNIDQVNLDGLLKLYPEFISITDRNHDMDNLLQSIRIADYIRANSSVDVV
IHLTGIDKDEKRVKEMIDLMQQHDIHSVLALRGDKLSQNDTAVTFPHADRLIEFINQKYP
HVNISGTCYLNSSDEEMKWLRQKIAKGCTNLISQFSFDANDYVDYLNQIEIDTPIWFGIM
PVISISQAEKMLNMTHSTAPDELNALMNQHDDEFSEKSVQYTAGMINKIKQAGANHIHLY
SLNNAENTKRIINKI
>A0A0Q8JD86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. Root690|TrEMBL
MLPISFEFYPPKTDEQRGQLDKTALKLKPYAPSYVSCTFGAGGSTLNYTPETIRRLRAKH
KLDAAPHLSCVGGTRAEIRELLQLYREIGCKRLVTLRGDLPSGMASAGDLRYANELVEFI
RAETGDHFHIEVAAYPETHPQARDAHSDLENFKRKVRAGANGAITQYFYNADAYFRFVDD
VRAAGIDIPIVPGIMPISNFSQLRRFSDLCGAEIPRWVAQRMQAYGDDVDSIREFGADVV
ARLCSRLIEGGAPGLHFYTLNLSKPTLTVLSRIA
>A0A258K2R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azorhizobium sp. 32-67-21|TrEMBL
MTSPIRASRETSRPPVRVSFEFFPPKTEEMERTLWASIDRLAPLGPSFVSVTYGAGGSTR
ERTHATVERIARETGLAPAAHLTCVAASRAEIDEVVRDYAQAGIRHIVALRGDPVTGVGT
AYEPHPQGYAHACDLVAGIRRLGDFEVSVSAYPEKHPESPSLDADIDYLKRKVDAGATRA
ITQFFFENDVYFRYLDKVRAAGIDIPILPGILPVTNFKQAANFAGRTGASVPAWLLKRFE
GLENDPETRKLIAAAVAAEQVTDLVDRGVGDIHFYTLNRADLVYAICHLLGLRPGAAETP
AQRLAG
>A0A0S8FTM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR_3 bacterium SM23_42|TrEMBL
MLRDKILKKKIITLEILLPVSFGLDELLSDIKYVSAFIDAVNLPSNPLGKLRPDALSCAH
VIQDCLNIETIPHFVARHHTLLGYESRLLGARTLGIENILCVTGDAPSEGRSAFELDSSK
LLEIAKNLRQGQTSARKSISPIDFCLCTSFNPNVPNVQGEFVKAASKYHCGAEIFFTQPI
FAPERALVVFRELRARCKNAKIIAGLSFLYTKKRAFALMKFLGIPYEYIARVEVEDEGEM
LLATAKKIAKHVDGFYVITIAKYRAAAGFLKKLRKLLRC
>A0A2N2F2H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium HGW-Elusimicrobia-1|TrEMBL
MKKISDILSSGKTTLSFEFFPPKTPPGRIKLYEKASRLTELSPDFFSVTYGAVGGTREFT
EEVAGELQNRFGVPVMQHLAAVGHSAADIRNMLDKMKVRGIRNVMALRGDVPDGVSVSSV
EKFPYAADLCRFIVSEYGDYFSVGVAGYPEGHPDTPDPDVGAEHLKMKIAAGGEFVVTQL
FFDNDKFFRYMRMLAAHGLKARVIPGVLPITDYGRLLSFCQKCKVDIPEEVHKRFRPIAT
DAAATFKEGVALARAQCDDLLSRGAGGLHIYTLNQSEAAASTVEGLIK
>A0A8I1NHC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIGEIITAKRPVFSVEFFPPKTDEGRVQLFETARTLAELELDFVSVTYGAGGSTRDGTV
DITTALKDEVGLEVMAHLSCVGETAEGLDATLDRLREAGIDNIFALRGDPPRGEADFVQP
EGGFGSAADLAGHISANYDFSIGGACFPEVHPEAPDLDTDLTYLKTKVDAGAEFLITQLF
FDNRAYFDFVEAARAKGIEVPILAGIIPVTGYAHTKRICSLCDASIPVELEAAMLAAEGD
PEAEFNLGVAYAAQQSAELLAAGAPGIHFYALNKAPATRAVLGALRAAQPWRGARGQSLT
Q
>A0A7V9HS92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MISRGGRRTSFPPPGPSHLGRARRVHPLLRPDRAFRDRGFLLPGDPSRGQVRRGRHRLPR
GEGGRGCRVPRQAVFFDNDVYFEWLAAVHEAGIDVPVIPGILPIISRRACIASARSDARI
PDRLDEQLAALGGDEEAELAFGIAYASRRCEQSARNPLLRAQSPGVGQRGPRGPACRRGP
VKSCP
>A0A1B0FLJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glossina morsitans morsitans|TrEMBL
MSSNITNTTHLGAHFLPKIAAAPLETAKCSYEPKFRFNEQQLRKYPKTQQLKIAVAEKIE
KKEYFYGIEILARSHNPKLMLDYTKFGKMLPLFTSLVWLGLDYSRVANVEKVESVRVAKK
LKDNQREMLIAPHLSCYGLDTKRLKEFTELNFTNIVIVRGDQYDNEQEFKYASQLVAQIR
RECQDSITLAVAGHPEGHPSISTMQEDMKFLIEKINGGADLIITQVCFKAQALIDFIKSC
RLHSINIPIILGIYVPDNIKSLQFLMELTKIEMREEDLQQYRYYASKGTDEFRFFAAQKV
TEMILTVLKTKDINIYGIHFFTMNKFGMVTKVLEELRKYIKI
>A0A7W0S1K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIDEIFTTKAEPVFSFEFFPPKSDDGERNLFRALEELRPLQPDFVSVTYGAGGSTRDKT
LEIVAHIHREFGLEAMAHFTCVNATVEGLRSTLDEMRALGVENVLALRGDPPGGADVWTK
TEGGLEYSRELVALIDAEYEFAIGAACFPETHIHALDADSDLRYLKEKVDAGARFLITQL
FFENERFDEFVVRAREIGIEVPIVPGIMPITNVGQIRRITELCGSELPPRLLEQLEMRAD
EPDAVAEFGVAYATLQCADLLANGAPGIHFYTLNRSPATRAILSALKLMRPWERAGAPSP
A
>A0A7V9HDS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIDEAIAQADQPTFSFEFFPPKTPEGETNLEAALSELQHMEPTFVSVTYGAGGTTEEKH
RTVETVARIKERHGLEAMAHFTCVGATVDELRRMLDRMAEAGVRNVLALRGDPPPGQEDW
TATEGGLSYSRELVELIRDEYDFAIGAAAFPETHVHAESPEVDLAYLKAKVDAGVSFLVT
QLFFDNDDYLDFVARARAAGIDVPIIPGIWPITNYKQIARVTSLVGSRLPEPLLSELDAR
VDQPEAVAGFGVAYATLQCADLLARGAPGIHFYTLNKSPATRAIMSALRAMTPWRGAVPV
>A0A6B9YM51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edaphobacter sp. 12200R-103|TrEMBL
MSENILYPTHGSKAVERLFQGAPVLCDGAMGTMLYARGVFINRSYDELNLTQPELVREIH
LEYLQAGAEVIETNTFGANSFRLEHFGLRDKVREINLSGVRLAREAVNQIRDKQGVEAFV
AGAIGPLGVRLEPLGKVGLDEARAAFAEQIIALTEGGPGVGVDLLSIETMTSLIEAEQAI
AAARAVAPGIPVIVMVTVDEEGNCLDGATAETAARRLSAAGAEAVGCNCSAGPATVLSVI
ERMRPMTDLPLVAMPNAGIPRAVEGRTIYMTSPEYMASFTRKLVKAGASLVGGCCGTTPS
YTRAMRSALRAMDAMETGAQVMESRSETPSAPKVTPPPLAQRSKVGAMIAAGEFISMVEI
VPPRGIDCSREIRGAEQLHKLGVDAINVPDSPRASARMSAQSLCVQIQQKVGIETILHYT
CRDRNVLSIQSDLLGASSIGLKNILCLTGDPPKLGNYPDATAVFDVDAIGLVNIVRNLNC
GLDIGKNSIGESTGFAIAVAANPGVPDIDQEVRRFAYKVEAGAEFAITQPVFDLRVLEEF
LRRVEGFRIPVIAGIWPLTSLRNAEFMKNDLRVSMPDEIMARMARTSSPEAARAEGIRIA
QEMLAEARPMVQGVQVSAPFGKGKYLAAAQVLGLTEGVEVPRG
>A0A4R4PHZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 8K308|TrEMBL
MALGIPSTMTDRAETVRELLSAGERSFSFEFTPPKTAAGERTLWNAIRRVEAVAPTFVSV
TYGAGGSSRERTVLATERIATETTLTPVAHLTAVNHSVAELRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWRRHPEGVTYAAELVSLIKESGDFCVGVAAFPEMHPRSTDWESDVRHFVN
KCRAGADFAITQMFFHAEHYLRLRDRVAAAGCDVPIIPEIMPIANVRQIERFKQLSNSTF
PPELEKAILAVKDDPMAVRSVGIDFATELCARLMDEDIPGLHFVTLNTTLHSTATLDVYK
NLGLHQRT
>A0A1F8SXC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_19FT_COMBO_55_16|TrEMBL
MTTNGNGYLVGSNLEKVLRAGHFAVTGELGPPQSADPEVIRKKAALLRGYCDAVNITDNQ
TAIVRMSSIGAGAIVVQEGLEPVIQMTCRDRNRLAIQSDLLGAFALGMRNLLCLTGDHQT
FGNHPNAKNVFDMDSIQLVQTVTAMRDSKVFQCGDAFKGPEPRFFVGAAAAPFADPLEFR
PYRLAKKVKAGANFIQTQLIYDIEAFQAFMEKVRKLGVHEQTFILAGVGPLKGPAMAKYM
KDNVPGILIPDGLIERMNRVGAPWAGKSKDELTKEDKKARSEAWQAEGIQITIELIQQLR
QIEGVAGVHIMAIEWEEAVKPIVEGAGLYPRPVVTDPVPQPA
>A0A2V2FWD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales Family XIII bacterium|TrEMBL
MKLSELLKQNKLSLSFEVFPPKTDTAFESVKRATEQIAELHPSFVSVTYGAGGGTSKYTL
DIAKNIKQEHGVPTLAHLTCVSSTKATVKERIEDIKNAGIENVMALRGDLTPELEKSGLA
DCDYHHAAELVYELAESGAGFCIGGACYPEIHPESANQKEDIKYLKEKVEAGCEFLTTQM
FFDNNLLYNFLYKIREAGITVPVIPGVMPITNANQVERAVKLSGSFVPQRFKSLVDKFGA
NPAAMKQAGIAYATDQIIDLYANGITNVHVYSMNKPDVAAKIKENLSDMLGYEL
>A0A0E3Y6V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blochmannia endosymbiont of Polyrhachis (Hedomyrma) turneri|TrEMBL
MDVLYVGSELLDDQFMLNVSNGINVSFEFFPPHNEGMKKIFWQSITKLSELAPVFVSVTS
GVNFRNSDYVYNIIQEIKCRTGWTVAPHLTCIDVTLQQLTALAEKYWNNGIRHIVALRGD
PVDKVCQSAMYAIDLVVLLKRIANFDISVAAYPEVHPEAISAQSDLLYLKKKIDAGANRA
ITQFFFDVEKYLKFRDLCVSSGISIPIVPGILPVFDFCQLKRFLTFTRVVLPRWVLSVFD
GLESDKNTQKMIGIVIAMEIIRILIREEVRDFHFYTLNRFELTYAICSMLGVRKNSKGV
>A0A7S6MBR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaeraceae bacterium|TrEMBL
MHIADIFARHRTTISFEFFPPATEDGWEALFGRIADFEALAPSFVSVTYGAGGSTRQRTH
DLVVRLRRETTLDPIPHLTCVCHAPADVDAILARHAEAGISNILALRGDPPRDRPDYRHD
TADFRHAADLVRHIRLFNESGRHPDRRGFGIGVAGFPEGHPDTPNRLREMDFLKAKVDAG
ADYIVTQLFFDNRAFFDWRERCELAGITAPLIAGIMPITSIAGMKRMADLAGGANFPARL
QKMLLRAQDDPDAVERVGVHWATEQCRDLLDEGVRGIHFYTLNRSSATKRIYETLGVKDS
SALTR
>A0A8G1KWJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania aurantiaca|TrEMBL
MSPTLDQMREAQRALEARLFSGLPGDIDVSFEFFPPKTEKMAETLWSSVKTLEPLDPRFV
SVTYGAGGSTRERTHDAVRRIVAETGIPAAAHLTCVQATREEVDEVARQYWEEGVRHIVA
LRGDAPDAEAGYAPHPGGYENAADLIAGLKKIADFEISVAAYPEMHPDSPDRQADLDNLK
RKFDAGATRAITQFFFEPECFFDFRDKAAAAGIDGEIVPGIMPVMSFAAVQKMSGLCGTA
IPDWMEGLFDGLDERPEARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRPKA
>A0A7T4DJ98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei|TrEMBL
MVESTAVRLLEDFSLEMTGKDVDALREAAAVIPTGTRINVTYLGNEDLPMRVAAAEAVRE
LGFVPVPHISARRIASEPSLREFLSALQDVGASEHVFVVGGDPAVPEGPYPDSLTIIRSG
ILQDYGVREVSIAGYPEGHPDIDSATLAEHLAAKSASLSDQGLGQVVLSQFAFDADRVTA
WIEEVRAAGIDAEIRVGVPGPAGVKRLMGYARRFGVGASAGIVRKYGFSLTNLVGTAGPD
RFVSELATDLAGAGDAGTVKAHFYTFGGLAATAEWVRDFVGEA
>A0A1B6YU11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jannaschia sp. EhC01|TrEMBL
MHTPNVSFEFFPPKSLDGSFRLWETLGVLAPLDPRFVSVTYGAGGTTRKLTHEAVTAINS
NFGVPVAAHLTCVDATRTETMEIADQYAEAGISQIVALRGDPPKGANGFTPHADGFASSV
DLVEALARTGKFDIRVGAYPDPHPEAASMQACVDYLKRKIDAGATSAITQFFFEADTFFR
FRDACVASGITAPILPGILPIEDWTRARRFAASCGAVIPTWLDEAYASATRDGREDLLST
AICTELCTDLIEGGVEDLHFYTLNRPELTRDVCAALGVARKTVLAEVA
>C0ZBM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)|TrEMBL
MTTRKKDLRAYLKDHLLVGDGAMATQLHGLGVPVGVSFEELCLSNPRLVHEVHTSYYQAG
ARFLETNTYSANRDALSRYGLEHKVARINRLAVAIAREAAQDDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGVDGLILETFLDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYALTDAFSELKAAGADVVGLNCRLGPAELLRSFENTVIPEDALLSVFPNAGRLG
MTDGEYAFKSSPEYFGQSALRLREQGVRLIGGCCGTTPAHVKAIADALESLEPQARVNPT
IVAGDRPTISVQNTREREKPSIVERVKTATTIIVEFDPPRDLDADQFLHGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKSRHGIDPLLHLACRDRNLIGQQSHLMGLNALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMDAAVARLEKKVEAGADYIMTQPVYDAESIRNVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSTEALERMKKVQGEAARQEGIAIAKELVDTAVRYFNGIYLITPFNYYE
MAAELIQYTRQQSSLVRMAQT
>A0A7R7W9N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus kawachii|TrEMBL
MAQALRPLFVTVTWGAGGSTAARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEA
KVLGIRNILALRGDPPRSEEYNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPE
GHPADNFQDVQDPARDLPYLIEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTI
PIVPGLMPIHSYKILTRVTKLSHVKIPPQVLSKLEEVKHDDDAVKRIGVDIITDLVYGIR
DLVSPGLRGFHFYTLNLEKTVSFILERCELIPPYTEIDDSDALVDGGNLSAMDSSSYIAP
NGAPIRTLASRRSSVSSIPHNRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTT
LQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTRE
DISTLFRRHVSGELHMVPWSEGGAEEDSNGLNAETAVIQPELLTLIDKKGWWTLASQPAL
NGVRSDDPVFGWGPPGEGFVFQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKG
DFESSLPGPNPDDPDPIDINPANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWD
EWRRIYPKNSATERFLDETKNDVWLVCVVGQEFGAGTEAGSEEEEDEKKWMWRELANSQ
>A0A8B5ERS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. US42a|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSVNSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A2S4MQ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea psychrotolerans|TrEMBL
MNAFRPSRHGSRRPKVSFEFFPPKTAEMETALWESVRRLEPLVPSFVSVTYGAGGSTRER
THATVKRMVEETALKPAAHLTCVSATCDEVDDVIRSYWEAGVRHIVALRGDPAGGLGTAY
EPHPQGYHQTSDLVAGIRRVGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRARGIDIPILPGIVPVQNFKQTANFARKTGASVPQWLADRFEGL
EEDAATRRLVAAAVCAEQVLDLIDRGVSDLHFYTMNKADLVYAICHLVGLKPEKTAAQAV
AAE
>A0A086MRU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces mutabilis|TrEMBL
MTTFSYEFFPPKTEKGERTLWEAIRRVEALRPDFVSVTYGAGGSSRDRTIAVTRRLAAET
TLRPVAHLTAVGHSVAELRRIIGQYADAGIRDVLALRGDPPGDPNGTWVPHPDGFTHARE
LVELLRSLGDFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFHVEDYLRL
RDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSGAAFPEDLAHRLERARGNPAAGHRIGV
DHATAMAERLLAEGAPGLHYITLNRSTAALDIHRNVQTIRSLSAR
>A0A2D6Y7A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. ARS1019|TrEMBL
MDLNLTSALQRAVESGGMVLTAEVMPPRGADPSHTLAMAEALRGRVHALNVTDGSRAVMR
MSSLAVCRLLLDAGLEPVWQLACRDRNRIALQADLLGASALGIRNLLCLTGDPVRAGDQA
DARPVNEFESVKLLQQVSALNRGEDPVKGALSDGATTLFQGCAADPHSRSWSGLQRRLIR
KCEAGARFVQTQMVMDPAVLERFQNELAKPLELPVLAGVFLLKSAKNALFINRMVPGACI
PDDLIQRLDQATDPAQEGIAIAAEQVKRYSGLVQGVHLMAIKAEERIPQILDRAGVSLPP
G
>A0A0C6FYR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium aquaticum|TrEMBL
MYPTAFRPSRESRRPIRVSFEFFPPKTPEMEATLWSSIERLAPLGPSFVSVTYGAGGSTR
ERTHNTVSRLVRETELKPAAHLTCVAATKGEVDEVVRAYHEAGVRHIVALRGDPADGVGT
AYTAHPGGYERSCDLVAGIKRIGDFEVSVSAYPERHPEAGSLDQDLDALKAKVDCGADRA
ISQFFFDNDLFFRYLDRVQSRGIDIPIIPGILPVQNFKQAANFARRTGASVPDWLAARFE
GLEDDVATRKLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRAAPAAAE
KAAA
>A0A2E2B409|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaeraceae bacterium|TrEMBL
MHIRDIFDQQPTTLSFEFFPPKNEKSAESLYQAIEQLEGLKPSFVSVTYGAGGSTRDLTH
DLVVRIQKQSKLDPIPHLTCVCHQQDEIQQILERYAAAGVGNILALGGDLPFDKPDYDRS
QDAFRHAAGLVDFIKKFGEQGNHPDKRGFGIGVAGFPEGHPGTPNRLLEMDYLKAKIDAG
ADYICTQLFFDNRDFFDFCERCELAGINVPIIAGIMPVSTVTGMKRMAELSAGSRFPAPL
MRAIQRVQDDPEAVKQVGLHWATKQCMDLLDNDVRGIHFYTLNKSDTTQQIYLRMGLADS
TPVTGK
>A0A269ZDM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei|TrEMBL
MVESTAVRLLEDFSLEMTGKDVGNLQEAASAIAPGTRINVTYLGNEDLPMRVAAAKAVGE
LGFTPVPHISARRVTSEQALRDFLAALAEVNATERVFVVGGDPATPEGPYPDSLSIIRTG
ILQEYGVREVSVAGYPEGHPDIDTATLWEHLRAKTASLAEQGLSQVVISQFAFDAERVSE
WVAEVRDAGVTGDIRVGTPGPAGVKRLIGYAKRFGVGTSAGIIKKYGFSLANLVGTAGPD
RFITELAADTQVAGDGRGVKTHFYTFGGLSATAEWIRDFSRGA
>A0A329J0E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. RIT 412|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATARTLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
KEVNIPSAPHLSCVGDGKADLRGLLSQYQDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGGHFHIEVAAYPEMHPQARSFEEDLKNFVRKANAGADSAITQYFFNADSYFY
FVERVQKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYNDDSASIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLALWNNLKLPR
>A0A2T3KS08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium leiognathi subsp. mandapamensis|TrEMBL
MSDQYLSSQESELRVRYNDITRGVYFIGTTPPKTSTPLEDVEGIADRLVDRICDLAIDGL
IVYDIQDEASRTNKPRPFPFKSTHDPRHYSSLLNKKTDKPVITYKSVVQSETEEFDAWLN
EAWDEYRVRDMVLVGSPSAKNEVSLPLSAAYQTLADNRNNFFTGGIMIAERHAKKGNEHE
RLIEKYKQGCNFFISQAIYDTQATIDILTRYAIECKEQGLKPQRIILTFSPCGSAKTLEF
IEWLGVSVPEATSLRILNAENPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRKE
EIDGSILLYKLLRSSMDSHLAKHEFRVLKRKARANKQASV
>A0A2A4F1U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia acidicola|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRLTCVQLAALKPKFVSVTFGAGGSTQQGTLDTVVDIAK
EGLEAAPHLSCIGSSRENLRAILNEYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRSEFGDWFFIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNPDAYFRFID
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARQLESFGDDRDAIRAFGLDV
VTNLCRRLIDGGAPGLHFYTLNGAAATKSICERLGT
>R5N663|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:180|TrEMBL
MLITETFKDNGLSTSFEVFPPKNNAPYKPVEDAVDKLAVYRPDFISVTYGAGGGTSVNTP
KIAAHIQNDLSIPALAHLTCASSTKKELDKIINDLGAAGVNNILALRGDLPDGYDPDNPD
YYHYAYELIEAIKSKGDFCIGAACYPECHPEAESLQKDIENLKIKVDSGVDFLVTQMFFD
NNVMYSFLYRALKAGIDVPVIAGVMPVINAKQIKRSCALSQTSLPPRFRRMMDRFIDNPE
ALKQAGIAYATEQIIDLISNGVSGIHIYTMNKPEVAGKIMENLSSVLSAR
>A0A161SAW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myroides marinus|TrEMBL
MKVTEHIQKANGKTQFSFEILPPLKGQNIQGIFDSIEPLMEFEPPFIDVTYHREEYEYKE
AGNGLWEKRVVRKRPGTVGICSAIQNRFKLDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKNETYFKPEPKGNKYASELVTQIAELNQGIYLDPELENTSKTDFCIGVAGY
PEKHMEAPNFDTDLKYLKQKIDNGAEYIVTQMFFDNSKFFEFVDKCRAIGIDVPIIPGLK
PLATLSQLNLLPQRFKVDLPDELVAEVLKAKDNTAIREIGIEWCAQQSKELIAAGIPIVH
YYSMGKSDNIIKIIKKAI
>A0A520Q7N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaeraceae bacterium|TrEMBL
MSRIDQMFSERGPTASFEFFPPKDGEAWDALFSGISAFEQLQPSFVSVTYGAGGSTRART
HDLVVRLRSETSLLPMPHLTGRGHTKAEMESILVRFAESGVDNILALRGDPPKDGDPGPG
DFPHAIDLVRFIKSFNESGGHPNGGFGIGIAGYPEGHHETPNLLTEMDHFRAKVDAGADF
VISQLFFDNRRFLDWRDRCTMAGIQIPLVAGLMPITSAGGMRRMAELAAGTLIPARLLRG
VLDREADPEMVEAFGVLWATEQSRDLLDHGVAGLHYYTLNRSRAARRVYETLGIRDSRSF
MTGS
>A0A7X4EC94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0673_bin_12|TrEMBL
MTPRTLQHTLVQGQFAVTVELNPPKGTDVSELLETAKSLSGRVHGINVPDNAAAVLRASP
VAVARLLYEQGHDPVLQVTCRDRNRLALQSDLLGAHVLGIRNVLCLTGDSPGTGDHKDAK
PVFDLDTVQLMHAVQELNEGRDLAGNALEGRTAFFIGGAAAPGAEPAELLHKKFEAKVNA
GAEFFQTQPVFSAKVIHPFMEAVRPYSRKVLAGVLVLRSVKMAEYVNARVPGIDVPDEIL
QELRNAGDARVSEAGLEIAVRTIRAVRPFCDGVHLMAGRLAHRLPEIIRKAELS
>A0A840FWF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclus tenuis|TrEMBL
MTAAFAQSRRCFSVELFPPQTTEGADKLRAVRHQLALLQPEFFSVTFGAGGSTRDRTFDT
VLEIQAEGQRAAPHLSCIGATADSIRELLEGYRARGIRDIVALRGDLPSGMAEPGAFRYA
SELVEFIRTESGDWFHIEVAAYPEVHPQAANPQADLAAFKRKVDAGADAAITQYFYNGDA
YLRFVDACLALGVNIPIVPGIMPISSYTKLARFSDTCGAEIPRWMRKKLESYGDDAASIR
DFGLDVVAALCQRLLDAGAPGLHFYTLNQSGLTSELWQRLGLPAAPAAGSGV
>A0A7C9VSM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Afipia apatlaquensis|TrEMBL
MDQNTQSEQRPVETPAPRRKTGYRNQIREALQTGTFCYTLEYVPDLSSSDPHVLDELRRN
SELLGRDPRIAGVNIGDRVKSLDSFDTVLCGRIAADASGKVPLLHLAGKNRTLDQARAVI
ERALSHGLENMLLLTGDGIMEKRAERFRYQESVNAIVDAKRMSPSCLVAGAIAPFKYREE
ELANQYLKMAKKVGVGVDYLITNCGWDMRKLEELAWYRDARGFRQPLVANLLMPTMGWAR
GIHARRLPGVFMSDDLFNKICEEHAQGRSEAKRMAWNRLALQIVGAQLLGYAGVHMSGIE
NYGDLCTAIEMTEALARELPSLELWKEAWNDAHRLSDRRVVDFAPPGGLYLFSADAKPPP
GSLNHLPEFGDVKPSDAELTKYSRMKSLHHAVFEEGTAGAAVAGATVRALDKTEIGRSAL
LKLEKVTKHASLGCETCGFCRIEYLFYNCPETCPKGLANGPCAGTDQNTCEFKDRECIHN
RKYRLAKSQGRLDELERKIVPSVEGTRGTSSWINHFEGRTPKVR
>A0A844X5H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella sp. Lep-s5|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKNSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSLKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGVDNVLALRGDISPNVQPKDDF
RFASELVTFIKENGDFNVIGACYPEGHLEAATLKQDLLHLKEKVNAGTDQLISQLFFDND
YFYAFLDKARDIGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMAKYEHHPEAF
RDAGIAYAIDQIVDLVSQDVDGIHLYTMNNSYIARRISEAVSTLLAVPKSE
>A0A7H0HQQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces genisteinicus|TrEMBL
MALGTASTRTDRARTVRDMLATGETTYSFEFYSPKSDKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRVGTVKATQKIASDSTLTPVAHLTAVGHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMADWVKHPEGVTYAAELVELIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVD
KCRAGADYAITQMFFSPDNYLRLRDRVVAAGCETPIIPEIMPLTSVRQLERFPQLSNAQI
PADLKDRILAVKDDAAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHEQS
>A0A5R9M967|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. So13.3|TrEMBL
MRTLLQRVRYEVLPAGPTEDQVLAHVPRDVVITVTASPVKGLDPTLDLTVRLAGHGYRVV
PHVPARLLRDGAHVAEIADRLRASGVEDVFVPAGDANPSAGAYEGALPVLRQLSELGSPF
RHVGITGYPERHPLIDDDITIQAMWEKRVHATYIVSNLCFDPQVLGEWVGRIRRRGVALP
VHVGVAGPVERTKLLAMATKIGVGESTRFLTRHASWFVRLSAPGGYSPERFLTRTAPALT
APSAVVAGLHVFTFNQIAETERWRRAMLERADN
>A0A8I0VNU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fulva|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SQVQVPAAPHLSCVGDTKAELRALLAEYKQVGIKRIVALRGDLPSGMGMASGEMRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEADLANFAHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEELLQGGAPSLHFYTLNQAEPSMAIWNNLQPSR
>F9MGW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis SK569|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERLYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A3D1YNS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halieaceae bacterium|TrEMBL
MSAAKKLLESLYFEVIPMKGLEEKLDVLKAGDRVGITCSPKQGLQFMLDTVAKLSDRGFS
LTPHLAARQVMNKQHLKDIVSQLTDSGITSVFVPGGDLDEPMGEYDSSAAVLRDLAEMDH
PFTRIGVASYPEGHPAISDDLLFEALSAKQGIATHMVTQMCFDMPVLVKWLSEMRDRGIT
TPVWIGLPGVMDRMRLFKTSLRIGVGQSAKYAKKQKGLIGMFLRSPTYKPDSLFKELKPA
MNDERMAIEGLYMFTFNQIDNTVQWSQEQIKRIK
>A0A377I1C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parahaemolyticus|TrEMBL
MSFATDIDHLNQNIADLNGKINVSFEFFPPKNEKMENLLWDSISRLAPLKPKFVSVTYGA
NSGERDRTHSIVKSIQQETGLIAAPHLTGLMQRLTSCARLPKIIGIMVSVIS
>A0A2R9U918|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. 71-36|TrEMBL
MTVLPLLDACPKRMEYGPCGGVGFDGSCEIDASHSCAFLPRGTVPWTGIDRATPVDPGPR
TAAAAETLASLGTRPWVVADLPARALSVASIDSCAAVLAGEVDAVLAGDAGTARVQFPPA
YRAHLLQRAGLRVWTGINMRDRNRVAIEGELAALAVEGVAGVHCVTGDHTRTGDRPDAAP
VFDLDSTEAAALARAAGHVVSVAASPAAPPVDRRAARLREKLHAGADVCFVNHAGGAEPV
RRFIDAVAAPVSYIPCVPVVVDHASADVLESFTTLVLPDGFLERVRSARDPRAEGIALAV
ALAEELLALPGVVGVNLSGGRDGGEESFAEAQAEIARRLR
>A0A2K1Q731|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mixta theicola|TrEMBL
MSFFHANQREALNQSLAELNGRINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNSGIRHIVALRGD
LPAGGGKPEMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPAWMNSMFA
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPTAALVA
>A0A0D0L3H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fulva|TrEMBL
MQKKTNVSFEFFPTKTDAGHEKLLNTARELAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELIELLNLYKSKGINRIVALRGDLPSGMGMSSGELRHANDL
VELIRQQTGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGASSAITQYFFNADCYFY
FVERVRKLGVDIPVIPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDTQSIQRFG
EEMITAMCERLLQGGAPGLHFYTLNQAAPSLAVWKNLQG
>A0A3N2KUU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Isolate-039|TrEMBL
MRVIDHLQANPGRTAFSFEILPPLKGNSIEKVYNIIDKLRDFDPKYINITSHHSEMIFKE
MPDGSFRPQKMRKRPGSVAIASAIQNKYGITAVPHIICKGFTRDETEYALIDLNFLGVHD
LLLLRGDIKGPEKSDDPTKINRHATDLQAQVNDFNRGIYADGETFEPNATPFSYGMACYP
EKHEEAPNMDSDLYYAKQKVDGGADYLVTQMFFDNSKYFEFVERCRKAGITVPIVPGIKP
VVFANQLNVLPRVFRSDIPEAFASELRKCKDDAEVREVGIEWCIGQCRDLIAHGVPSIHF
YTLMASESVRRIAKEIY
>A0A1M5REP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidibacter thalassicus DSM 15285|TrEMBL
MSLLRKALENGEFAVTAEMAPPKGIDFNHLVECAKAIKGRVHGVNVTDFQSAVMRTTSLA
TCKILKDEGLEPVLQMTGRDRNRIAIQGELLSAGLFGIKNMLALTGDHTVVGDHPGAKPV
YDLDSVGILDVATTLMNGKDMVGNELKGKPEFFLGACVTPRYTPLEIQILKMEKKIKAGA
KFFQTQAVYDLDTMREFREKTKHLNCKVLAGIIPLKSVGMARFMNNNVPGIYVPDDVIQR
IKGAENKVQEGIKIAGEFIQQLREENLCDGVHIMAIGAEENVPAILDVAGL
>H1LV02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium oral taxon 082 str. F0431|TrEMBL
MENAKKIKAAGADIITIADNPIARARMDSCLLACKVRNELDFDVLPHMTCRDRNVNASRG
LLLGANAMGVDNVLVITGDPIPNAQRDEIRSVFEFNSVKFANFINSLNDEVFESPMNICG
ALNVNAKNFSAELRKAKRKQENGVKVLFTQPVLTQRAIDNLKEARENLDVKIMGGIIPIV
SERNARYMQSEVNGIYITDDIVEKYIGKEREEAEEIALSMSKEIANEIYDLVDGYYLITV
LNRVSLMERLIKTVKDVCENK
>A0A1R0H9V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sphagniphilus|TrEMBL
MELSVEFFPPKTPEGESKLHMVRERLSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRDSVREMLNQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
TETGDWFHIDVAAYPETHPQAKSPASDIDFFVQKMKAGADSAVTQYFYNSDAYFRFVDEA
YDLGVTQPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDIASIRAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAITDNLNLAQSK
>A0A1W9KL27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium ST_bin15|TrEMBL
MSTPLSVSFEFFPPRNDDMERTLWESVERLAPLAPRFVSVTYGAGGTTRERTHATVTRLV
AETALQPAAHLTCVAATRADIDAIVEEYWSAGVRHIVALRGDALAGPGATYEPHPGGYAY
THDLVEAITRRGGFEVSVSAYPERHPDSPDWDTEIALLKAKRDAGATRAITQFFFENDLY
FQYVERVRKAGIDIPIVPGILPVQNFAQVANFAKRCGSSVPEKLARRFEGLDGDQQTRAL
VAAAVCAEQVEDLRARGVSEFHFYTMNRANLVYAICHLLGLRPQHLQKAA
>A0A7W1HE92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
ADVIGLNCGVGPTHILTALEKMRGATTKRLSAQPNAGLPRDVQGRQFYMCSPEYMSKFAK
RFIKAGATFIGGCCGTTPQHIKLISDAVRAISPRTAKAAVKAKETAKVIDLKPADVEIVP
PELRSNWSRKIARGEFVTSVEVLPPKGCDAAKTLESIKLLKTAGVDAVNIPDGPRAQTRM
SAQATAILVEREIGIEAVLHYCCRDRYLLGMMSDLLGAAALGVHNLLIITGDPPKMGPFP
DATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGRPTAFSIGVGVNPGAINVEEEIRRFEWK
VEAGAEYAITQPVYDTKQLRDFLKRVEHVRIPIVAGIFPLVSIRNAEFMHHEVPGVVVTP
EILMRMRIASDRSKEAARDEGIKIARESLTEVRDLIQGVQVSAPFGNVKYALQVFDVLDE
LKSTGEAAAIS
>A0A0U5B203|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldimicrobium thiodismutans|TrEMBL
MERKSHLESLLSAGKFAVTAEIGPPRNADSEVIKKKARLLKGFVDAVNITDCQTAVVRVS
SLASAVLVLSEGLEPVLQMTCRDRNRIGIQADLLGASALGIRNLLCLTGDHPKFGNHPHA
KPVFDLDSIQLLRLAKGLNEGRFENGEEIKGLRPYFFLGAAENPFAEPFDFRPFRLAKKA
RAGARFFQTQIIYNVDKFRKFMEKLKDLGLTEEVYVLAGITPPKSLGMAKYMKYNVPGLE
VPDEIIQRLESAKDKKEEGIQIAVDIIQQVKEIPGVRGVHIMAIEWEEAVPEIVKRAGLS
PRESIAEMHPPFVVEKVVEKIVEKPVEVVVEKIVEKPVEVIVEKIVEKEIPLEVEMAGEK
ISALIEILSDLKASLKNLRSGMESLEEGIVKLEEEFLGKKEARPIVREIPKPAVEVKPPV
KVEERPVEAKPELKAEPEVKPELKPEEKPEVKPEIKPEAKPEVKPEVKPEVKSEVKPEVK
AEPKPEIKPEVKPEVEPEPKPEVKPAEVKIGGLKGVYRPLSARASKIAQDLYLEKANGEI
REVQIGKGEKALKVGGISGINFHLFEGEMKNGLKIAFEILDVKPEDWPEHLSKYYSDVYH
DPGLWAKKCVEEYGAEAICLYLLGTDPNFLNLPAEHAKKVAEKVVSSVDVPLIVWGSGNA
EKDVEVLRDVADIVGVRGAVIGPVVEANHRTLAAVAMGYSIPVIASSPIDVNLAKQLNIL
LENMGLALDKILMDPSIGALGYGLEYTYSVMERIRLAALFAQDTKLQVPFICSIGKEVWK
TKEAGLPTDALMGDAESRGVLMEALTGVTLALAGGDLLIMRHPKSVELCKILFNGLSLS
>A0A2V8MGG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MAYCTCRKRLHSQNCEQWFKERRLYARSSEDKVPRNPLRESLEAGRFCHVVEIVASRISR
EARLLHVAAQLAVTPGVVAGSITSYAGGSAGQDPVRVGTAAKARGLTPNIHVTCVSKDRR
ELREMLHTISDLDIENVFALTGDYPKGSTPVFDMDSVELVTLMNELRQNEGLQLWIAVAV
TPFKYTEPDCVYQYLKLEKKFAAGADYAITQLGFDAKKFAELRRYLDDHGIQKPVLGNVY
VLGLKAAEKMSKGEPPGCWVAPELVEKIRAETKAKDSGEAARLERAARMVAILRGMGYAG
AYIGGTHKAEHVRWIIERGQQLAPQWEELASELSYSPKSAFYMYEPSTAPRLAPLGWRER
AVNAFWHVPSPKRIPEGGVLHKLAKTVFGWIDHRPSLARSLERAEFAVKSPAFGCQSCGN
CVIPDMQYVCPQTCPKQLRNGPCGGTNNGQCEVIPERSCIWVKVYERAKAANELESLKVY
IPPPDRSLKGTSAWINYFLNRDSRPGRPKLGAPTPTPAPIKEESKIKVAVPQ
>A0A7X8UBJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MNRFGRALLSGRTLVTAECLPPRGADADVMRELSASLPRELDGIVVPDNPDRVRASALSC
GALLARERGRSVIMAMTSRDRNRIGLVSDALGAAALDIEAILCLGGRHQSSGIAPEAAAA
RDLDSIQLTQALKKMALYGSSMNGRKLEPEIKLQIGATANPYLRPLDLNLLRVRMKVHIG
ADFLFTHAVFDLDGFGQWLDAVRSLGLDKRTAIIASVLPLGSVERARELDRSGIYGPVGE
GVIARLARSADPVREGILIAAEVAKKLKELPGIRGIHILSGGAESRAAEVMRQAGLPMVP
SPAN
>A0A2V8S6H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MFIMDDFRDILASDQITVFDGAMGTMLYSKGVYINRSYDELNLTNPDLVREVHEEYVRAG
AEVLETNTFGATAHNLQQYGLDARLREINIAAARLAREAAGTRAYVAGAIGPLSLRIEPY
GPTSFDEAKEMFKAQAEALLEGGVDLLVLETFSDISEIKQAIRAVRELCDLPIITQMTIQ
MDGNTSYGTTPEVFTARLDEWGADVIGLNCGVGPAIVLNAIEKMRGVTNRKLSAQPNAGL
PRDVQGRQFYMCSPEYMAKYAKRLIQAGVKFVGGCCGTTPAHIKLISDAVRAVSPRRQRV
PFSTQQPARIAELTPADIRVVPLAERSNWARMIARGEFVTTVEVLPPKGCAPEKTLESIR
LLKDVGVNAVNIPDGPRAQTRMGAQATALLVEREIGLETVLHYCCRDRNLLGMMSDLLGA
AALGLRNLLLITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGCPTSFC
IGVGVNPGAINLDEEIKRFEYKVEAGAEFAITQPVFDVEQLRTFLRRIEHVRIPVVAGIW
PLVSYRNAEFLHNEVPGVRVTPEIMERMRVASDKGKEFGREEGLQIARESLVEVRDLIQG
VQVSAPFNNVRYALEVFEVLPEFAARKELIASPSV
>A0A2W0BTG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSSSDSAFVGVLSSHPVLCDGAMGTLLYSRGIFINRCYDELNLSQPELILGIHQDYLHAG
AEVIETNTFGGNSFRLARHGCADKVRDINLAGARLAREAAKSFQSLVAGAVGPLGVRIEP
LGKIAREEARDSFRQQIEALVEGGVDLLILETFGSLDELHQAIVAARDVNPDAPVVAQVT
IDEDGSCLDGSTPEVFGPKLTDWGADVVGINCSVGPVAMLDAIERLRQVTTAPLSAMPNA
GMPRNVEGRNIYLCSPEYMASYARKFVAAGVRFVGGCCGTTPEHIRVMKSAIRVTNAKRP
PASLSADSKAPSAIQPVPIQNRSRVGEKLKAREFVTLVEIVPPKGVNPFKEIEGARYLKS
VGIDAINIPDSPRASARMSNQALCLLIQQQVGIETVLHYSCRDRNVLGIQSDLLGGYAIG
IRNLICITGDPPKMGNYPDATAVFDVDAIGLVNIVRNLNRGLDVGENPMGNATAFVIGVG
ANPGAPNIDEEIRRFEYKVEAGAEYAVTQPVFDLKLLETFLRRIEHVRIPVLAGIWPLVS
IRNAEFMKNELRVSVPDSILTRMASASNSEAARAEGVAVAREMLVAVRGEVQGAQISAPL
GRYASAADVLEALGGNGRKAAGQW
>A0A2V9K4S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MREPFSERLEKRVVVCDGAMGTLLYAKGISLSRCFDELNLSAPPWVKDIHVGYVKAGAEV
LETNTFGATRVRLAKFDLADKVREINLAGARLAREVAGSELWVAGAVGPLGVRMEPLGPT
SREEARAAFREQMEALVEGGVDLIIIETMVDLEEARQALLAAREASKLPVVVQMTIQEDG
TTPTGTPPEEFAPSLDEWGADVIGINCSVGPRAVLEDMAGYAARFIEAGARLVGGCCGTT
PEHIRAIKAAVKSASLSRTRLVAEPVARRVRALEPAPVERRSPLAQKLSSGAFPVIVEIL
PPKGSDPAREVEGARYLATHGVDAVNIPDGAGATARMSALSLAALLKQQVGVDVLLHYST
RDRNVLTIQSDLLGAHALGLTNILALTRDAAQYSTAEESAVFEVDAIGLVNILNNLNRGL
DVGANPLGTQTCFLVGASLNPQAVNLDEELRRFEYKVKAGANFAMTQPVFDVWGLREFLK
RVRSIAGREVSIVASLWPLTSFRKAEFLNNEVPGVSIPPAVMERMRKADTGDRARAEGVR
IAQETLVEIRDLVEAVQIASPFGRYAMAVEVAEVLKKEEVRSQKSGGSRQ
>A0A522M152|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MNPAATAARFADHVVVADGAMGSELFAALPEGTHLDLAPLEHPRRVLDIHLAYLAAGAEL
IETATFAASRPRLARLHAGDQVEAVNSAGVKLAREAREIAGTDCLVAGSIGPLAGVIDLD
EPAGPAAIAAAHAEQAAILAGRGADLLVLETFFRLDELLLAIAAVRGVTKVPVVAMLTFP
YDKLPESHPEIAAALRELFAHEPLAAGINCALGPQGTLDVLEALGEVPGLLAVMPNAGSL
LRRDGRIIRPPTTPNYFGGFARRAAELGAAIVGGCCGTGPEHIRAVAEALKGVRPVPARS
PRVAVAAPAPPPRLQARPASGLAAKLGAREFVRVVQLDPPRGTNSDRIVEAARALAATGR
VDALDINSNPLARLRMDSLWLAAEVQRAAGIETIPHITPRDTSLMGLQAQLLGAWRAGIR
NLLAISGDPSQLGDYPGVHDVYHVDIFELVRSVSRMAEGFDCAGNPIGEPPAYCLGVAVN
PAADDLGHEVDRLRRKADAGAHFVMSQVFFSWQPWERLLDRCGGALPLPALVAVWPLPSF
RLALRLNNEVPGIVVPDELLRRLEHAGAAAAKVGREVALEMLRGAPERAAGVYLVAPFKN
PAEVVELLDE
>A0A2W0BG53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSSSDSAFVGFLSAHPVLCDGAMGTLLYSKGIFINRCYDELNLSQPELILGVHQDYLHAG
AEVIETNTFGGNSFRLARHGCADKVREINLAGVRLAREAGKSFQALVAGAVGPLGVRIEP
LGKIAREEARDSFRQQIEALVAGGVDLLVLETFGSLDELHQAILAAREVNPDIPVVAQVT
IDEDGSCLDGSTPEVFGPKLTDWGADVVGINCSVGPVAMLDAIERLRQVTTAPLSAMPNA
GMPRNVEGRNIYLCSPEYMASYARKFVAAGVRFVGGCCGTTPEHIRVMKSAIRVTNAKKT
PTSVSAQNKMPSAIQPVPIQNRSRVGEKLAAREFVTLVEIVPPKGVNPAKEVEGARYLKS
VGIDAINIPDSPRASARMSNQALCLLIQQQVGIETVLHYSCRDRNVLGIQSDLLGGYAVG
IRNLICITGDPPKMGNYPDATAVFDVDAIGLVNIVRNLNQGLDVGGNPMGNAAAFVIGVG
ANPGAPNLDEEVRRFEYKVEAGGEYAVTQPVFDLKLLETFLRRIEQFRIPVLAGIWPLVS
VRNAEFMKNELRVSVPDSILARMASAANAEAARAEGVAVAREMLVAVRGEVQGAQISAPL
GRYSSAADVLEALGGNGHKAAAVV
>A0A7C2XP52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurivibrio alkaliphilus|TrEMBL
METAMKSGSRLEQVLRSGAFAVTGELGPPKSGNPEVVREKARLLKGRVDAVNITDCQTAI
VRMSSIGAGLITQSEGVEPVIQMTCRDRNRIGMQSDILGAAALGLKNLLCLTGDHQKFGN
HPGAKGVFDMDSIQLLGMMRDLRDQKKFQCGEAIKSHEPRLFLGCAANPFAGPNEAARAA
RLAKKVTNGADFVQTQIIYNVERFAKFMAAVRDLGLDEKVFILAGVTPPRSLGMARYMKN
FVPGLDVTDEVIKRLQGAKNQEEEGIDICVEIIQQCREIKGVAGVHVMAIEWEAATAEIV
KRAGLDKRPQVAEEPAPNVAAPAAAPIQVSDRSGEPATAGAGEAELAAARLEAEKIVAAA
REEAVRLKAGAAAAGSAPGHANIDQTDAQSAEAGEDEMNERERQMALESVR
>A0A7W0U4U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MALNGSDGGGISSALAALTRGFSVEVTPREAPKVPPFGEVLPAGTRIYITFLENTPFEDT
LALAARVVQQGMRPVPHLAVRAIPDRAALSGMLARLADIGVTEVLVIAGSVAKPAGEYDE
TMQVLTSGVLPEHGITRIGVAGHPEGTPDIGPTELAAALAAKNALAAEQGLDMYVVTQFC
FAPEPIIAWEREIRAAGIRLPIVIGLPGLTSPAKLLRFGMSCGIGPSLKVLRKQSGGVLR
LATSSVYHPDQTMLGLVRSRVDEPASLIQGVHFFPFGSLQRTAEWAGQLSAGQFVVEPDD
KLRVTA
>A0A2V9STU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MAGDFIDRIKKAPVLCDGAMGTLLYAKGIFINRCYDELNLSQPDFIRGVHREYLQAGAEI
IETNTFGGNSFRLARHSMADRVHDINLAGARIAHEAAKSFDVWVGGSVGPLGIRIEPLGK
TSFDEARAAFRQQIAALAEGGVDLIILETFGYIEELHQALLAARDVRANLPVVAQVTIDE
DGNCLDGSTPETFGPRLTEWGADVIGCNCSVGPVAMLDAIERVRAVTSLPLAAQPNAGVP
RSVEGRNIYLCSPEYMASYARKFVAAGVRLVGGCCGTTPDHIRVMKSALRAGEARSKTAV
TQVKSSVEPAAISAVPIEQRSRLGQKLAKGDFVTMVEIVPPKGTDIHKELEGARFLKSVG
VDGINIPDSPRASARMSNQALSVLVQQEAGIEAILHYTCRDRNVLCIQSDLLGAAATGIR
NLICITGDPPKMGNYPDATAVFDVDAIGLVNIVHNLNRGLDIGGNPIGAGTAFVIGVGAN
PGVPNLDEEIRRFEYKVEAGGEYAVTQPVFDLSLLENFLRRIEHCRIPVVAGIWPLVSVR
NAEFMKNELRVSVPDSILERMAKARNLEAAREEGIAIAREMLASVRDMVQGAQISAPLGR
YASAVDVLEALGTARPAASV
>A0A7W0KNF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MSATVRDRLAAGVVTFSFEFFPPKDQASEAVLWRTLRDLERLRPSFVSVTYGAGGTTREG
TVRVTERIATQTTMLPMAHLTAVNHSVAELRNVVGRFAAAGVRNILAIRGDPPGDPSAEW
VKHPDGIEFAAELVTMVRRAGEFCVGVAAFPYKHPRSADIEGDARYFVEKVRAGADFAIT
QMFFDAEDYLRLRDRVAALGCEVPIIPGIMPVTSMSTIERAPKLSGAPFPLGLARTFETI
AEDKDAVRAQGIIQASELCQRLLDEGAPGIHFITLNRSTATREIWANLRETSPVG
>A0A8I0D6A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. BW16M2|TrEMBL
MSLLKTTLDANAFACILEFVPKPGAERFATLETLMARTRLCGWPLTVAIGDRVGSALDMS
PLEAFSSLSKPVPALLHFSGKDRERRDLLAQLQRMDAAGLDQLLLLTGDRLPGHNPGERP
VRYLESVAALQIVRQARPHWLLAAALNPFKYQEAEGGAQYCKAEKKLAAGADLFILQLGF
DIDKHQEAFDWMQRQPRPKPLMACIMALTEGRAGMLDHVAGVTVTPSMRALLAAETAVSK
AYARERANHRLALQVIGLKLMGYAGVHLSGIHEVAQFEALEQAIDALQAQFNSLQDWAPA
WEAAWQAPGLTPVTFQPPGHAWRFGQRQITAANKEKVRYHLLSAMHHQLFSRTTTLSKAF
GWAVTRPLWANPTAAQWLHQLERRIKRPLVGCDTCGSCRLEDTLYICPETCPKGLANGPC
GGTNLDRCEFGDRECVHSAKYRLAVSVGRTEVLRERLIPCVQVENRHRSSWPVWFEAATS
KSPSLQPDVAPEFNE
>A0A2V8ZFD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIHDFNERLKNAILIADGAMGSMLHEAVGPQRCFDELNATEPEAVFRVHQEYIEAGAQI
IETNTFGANRFKLGPLGLGDEVQRLNSRGVKIAREARESAAREVLIAGSIGPLGLGVQAR
HPDDKEILDVFYEQALALEERGVDFYILETFSYIEEIVLAVDAIRSFSGLPIVAQLTYSE
EGTTHGDIRPTDAARQLKNKNVQVIGANCTLGPQALLPILQELAAVDDIRISAMPNAGFP
KREGDRIVYPKSSPEYFALFAREAAALGVRLLGGCCGTTPAHIHAMAEAVKSLRPAKTHA
ASPVVETAAKPAPISQREPESQFWKKLKKKEFAVCVEIDPPKGLSLDRIFEQVDKVMASR
EVDAIDINSGAMARVGMDALVVAGALEARGVETVPHLTTRDQNIIGLQAALLGAWTVGGV
RNILAITGDPPSVGDYPEASGVYEVDSVGLVKVLNRLNQGTDWAGKTLGGATNFAIGVAL
NPMADDLDNEIARFRAKVEAGAHFAMTQPLFDPQHWHAFLKKLGGKPPIPILIGVWPLNS
YKQALRLNNEVPGIIIPEPLLKSLERAGANARDCGFAVARDMLAWARTELAGAYLIPPFK
RYEEILEIL
>A0A7C2X449|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MLYCCALLSRATAARVPAASRMKIDEFVERLRNGVLVADGAMGSMIYEAAGPQRSFDEVN
LTQPEVVFGIHQAYIQAGAQIIETNTFGANRHRLAQIGLGDEVVRINHRAVKIAREAREA
APHEVLIAGSIGPLGLLRQGRTLPDEEIRAIYTEQAAALEERGVDFFLLETFTDLDQLLL
AIAAIRSFSALPIVASLTFNEEGTTFGGTPAAEAAWRLAQQPVQAIGANCTLGPQPLLPV
LRAMATSGLALSAMPNAGFPQRMGDRIVYPKSSPEYFAAFAREAVETGARLVGGCCGTTP
EHIRAIAEAVRHLRPAPTRAARSVQVETPPAQPPAAISRAREPESRLWRKLQSGQFVISV
EIDPPKGVALDRIFEQVDRVMASGRVDVVDINSGTLARVGMDAMMLAGALEARGIETIPH
LTTRDMNIIGLQATLLGAWSVGGVRNVLALTGDPPSLGDHPETSGVYEVDSIGLVRVLAR
LNAGTDWAGKQLGGATNFTIGVALNPVAEDLDYEIERFRRKIEAGAHFAMTQPLFDPAYW
EAFVEKLGAPPPIPVLVGIWPLTSFKQAVRLHNEVPGMVIPASVLSQLEQAGAAARDCGF
ALARRLLEWARGKFAGAYLIPPFKRYEEVLELLV
>A0A2V9CDX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIDDLNARLADSVLIADGAMGSMLHEVAGPQRCFEELNVTQPEAVFRVHQAYIEAGAQI
IETNTFGANRQKLALLGLGDQATPFNYRGVKIAREAREAAAREVLIAGSIGPLGIVRQVR
ELPAVEVAEIFKEQALALEERGVDLFILETFSDLDELLTAIAAIRSFSSLPIVAQLTFSD
EGTTFGGTRPLDAALRLKEKNVQVIGANCTLGPQSLLPLIGEMAAAGDVRLSAMPNAGFP
KRVGDRTIYPKSSPEYFALFAREAAALGARILGGCCGTTPEHIRALAEAVKTLRPGKGVE
VTAPVRAGPEAKRVAARQPESRLWKKLQAKHFVVSVEIDPPKGVSLDRVFEQVDRIMACG
KVDAIDINSGTMARVGMDALMLAAALEARGVETIPHLTTRDLNIIGLQAMLLGAWSVGGV
RNILAITGDPPSLGDHPETSGVYEIDSVGLAKVLTRLNQGTDWAGKTLGGATNFTIGVAV
NPVADDLDYEVERFLKKVEAGAHFAMTQPLFDPGHWHAFLKRIGGKSPVPALVGIWPLNS
YKQALRLNNEVPGIVIPAAVLKELEASGAAARDCGFALARRMLEWARTELAGAYLIPPFK
RYEEILEVIS
>A0A7Y1W2T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MLKPWTPISFEFFPPRSEAQVETLDATWRALAPLRPEYFSVTFGAGGSALDATHRAVMGL
QRESGVPIAPHLSCLVDSRDTLQSFLDDYTAAGVRRLVLLRGDRPKEDEARAPGPFLHAD
ELVSAVRELAGDRFSIEVACYPEFHPESATPESELQFFRQKVDAGATGAITQYFYNADAY
FRFIEDCERAGIRIPIRPGVLPITNYAQLTRFSKLCGAEVPQWICRRLEAYGDDLDSIRA
FGLDVVTRLCERLLRGGAPGLHIYTLNQSGPSLGLIERLGGSPALSEHESRDPARNHVGG
HTG
>A0A1F8P358|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_50_11|TrEMBL
MKISDAIKQTGHSLSFEFFPPKTKADENRLFGVACRLESFFPTFVSVTYGAGGGTSKTTR
EVVKRIHEETSLTLMPHLTCIGQVEDELRGILRDYREMGVENILALRGDPPQGMVITPGH
NGRCHARNLIEIVKSFNVFSIGVAVYPEGHSESPSLEKDIAYTKEKIDAGADFAITQMFF
DNRYFYQFMERAEQAGIRIPVIPGIMPVTDIEKIKRFSGLCGATLPKDLIVRMERATSKQ
DEVKIGINFAIEQCQDLIENGVRYLHFYTLNNADIVSEILRGLNLDAGSLSQSDTESAGD
LIAFAD
>A0A2G4JTT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. B11|TrEMBL
MTLPPIAPTGRRVIGPVALAGERTDRPRVSFEFFPPKTPAMEDSLWQAITRLAPLDPAFV
SVTYGAGGSTRERTHRTVKRILEETSLKPAAHLTCVGASRAEVDEVIREYWQTGVRHIVA
LRGDPPPGEGGLGAVYVPREDGYRNATELTQALRAVAPFEVLVGVYPEKHPESPSFEHDI
DVLKAKIDAGATLGISQFFFDIDAFLRFNDRVLAAGITIPIVPGIMPVTNFNGLKKMSAA
CQTTIPGWLANLFEGLDGDAETRRLIACSVAAEMCAKLQEQGFKDFHFYTLNRADLVYAI
CRVLGLRETASVAEIAA
>A0A3N5P7Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPFIRDIFADARRTRRPVISFEFFPTKTPEGERTLLEKTIPALGSLKPDFCSVTYGAGGS
TREKTLTIVDRIQRQHGLTAMAHMTCVNATREDTTAVLEQARALGIGNILALRGDPPGGG
SDFQKTEGGFEFSYELVRFIKDMGGFSIGVAGFPEGHIAQTEGKHTDWRHLKHKIEQGAD
FVITQLFFNNRDYFEFRDYLTSLGVTAPLVPGIIPILSATQIKRFVALCGADLPERLVRE
LDKRGDDDEAVAAFGIEYATRQCEELLREGVPGLHFYTLNKAKSTTAIVRNLGLLKEAAA
G
>A0A4R4CHK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. SRS-46|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTNLCQRLIDAGVPGLHFYTLNTAAATRTICERLGA
>A0A1C5Q1C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Blautia sp|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMENLPGTIDHLMKYKPEYISCTYGAGGGNVGANRE
VCQMIKKAGTVPVTHFTVIKNTKEGIKEQLDQYLAEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDMSATINMALSRNGCVMDSELCRLISRNWLFPN
PFAAKDADGKPFDMFYDDKIKRFKEEGIEYTIKQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A2V8XZJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
RIFEQVDKVMASRKVDAIDINSGAMARVGMDALVVAGALEARGVETVPHLTTRDQNIIGL
QAALLGAWTVGGVRNILAITGDPPSVVDYPEASGVYEVDSVGLVKVLSRLNQGTDWAGKT
LGGATNFAIGVALNPMADDLDNEIARFHAKVEAGARFAMTQPLFDPEPWRAFLKKLGNKP
PIPILIGVWPLNSYKQALRLNNEVPGIVIPEPLLKSMERAGATARDCGFQVARQMLAWAR
TELAGAYLIPPFKRYEEVLEIL
>A0A2E8E2S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSLRESFARDQSVIAAELRPPRAELDAAAGMDAWIDTYHAVRRLARDETFVFLTDSAVGQ
REEDSLRHLGANLGAQTPRDRVAPFLTTKHTLAHCLTYADRAKELGFEALVVLGGDRHVG
PPRCVEHGWELRALIRERQPDLLLGGWANPAQQAEQQVEYLLAPDATADFFLTQIVSHHT
PEPVASFLEASRRRNLSIPGLFGVFYYRSANPRTLAALGRFLDVPAEALTREFEAGATAE
EVCVRTIRALRDLGARHFYVSNLPVGHAAQTLSAIMGRT
>A0A3N5F7Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MALQSQLVGAAAAGISNVLILTGDDPKAGDQPDAKPVFDLDSSALMRTAASIRDKGELPH
GRKVGGKARFFIGCADVPIDPKPEWVPEALRKKLNAGAQFVQTQFCMDLSLLQRYIDRLQ
EQGIPVGKDVHLLVGVAPLASAKQARWIRDNLFGSVIPDALIERLEVAADPRSEGKSICV
DILRQLVAMPGVSGAHIMAPLNEASMPEVIREFRIG
>A0A2V8L847|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MDSVELVTLINQYRQAGMPFWISVAVSPFKYREADCAYQYLKLEKKFAAGADYAITQLGF
DVRKFRELRRYLDEKGIRKPVLGNVYVLNKRGAEKMAKGEPPGCWVAPELVDRIRKESLA
RDGGQAARLERAAKMVAIVKGLGYAGAYIGGTHKTEQLKWIIDRSEALAPRWEELAEEFN
YAPKNAYYMYESPAKPPKPLGVIPRTLNLFGRMFPVRQDTPLRRILVSIFSWIDRRPRLA
HNFERLEFAMKSPMFGCQACGNCVLGDMEYVCPQTCPKQLRNGPCGGTDNGQCEVIPEQP
CIWVKVYERAKAANELELLKVYIPPPDRSLKGTSSYINYFLKRDSRPGRDVDNPGPPLPS
SSPDEKNELHSSRSR
>A0A226N9Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callipepla squamata|TrEMBL
MVNENQHTCSASSSSRSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVHGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETSLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPPQQ
>A0A2V8XQI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
EAGAHFAMTQPLFDPEHWHAFLEKLGGKPSIPVLIGIWPLNSYKQALRLNNEVPGIVIPE
PLLKSMESAGADARDRGFEVARKMLAWARTELAGAYLIPPFKRYEEILEIL
>A0A1C5NDR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Blautia sp|TrEMBL
MKLSEAMKEKMLLSFELFPPKTEKGMANLPGTIEHLMKYHPEYISCTYGAGGGNVGANRE
VCQMIKNAGTIPVTHFTVIKNTKDGIKAQLDQYLEEGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDQYGDKFEIAVAGSPEGHIACRSLESDIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGVTMPVDVGVMPILDMSATINMALSRNGCVMDRELCRLISRHWLFPN
PFAAKDADGKPFDMFYDDKIKAFKEEGIEYTIKQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLV
>A0A2V9FBZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTQPLFDPEHWNAFLKKLGGKPVIPVLIGIWPLTSYKQALRLSNEVPGIVIPEPLLKSME
AAGSAARDRGFEVARHMLAWARTELAGAYLIPPFKRYEEILEIL
>A0A523CYV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKFPDFYASGDPVVSFELFPPHSDLGLATLEERLPKLIALKPSFLTVTYGALGTTRDRTL
QVVSEIRNTYGKEVAHHLTCVGSTREEIGQLLHDIRKENIENIVALRGDPPQGETEFKPL
KGGYRYGNELVEHIREFGGFGIAVAGYPEKHIEAPDFETDLNHLKRKVDAGADLIITQLF
YENRFFYDFVARCRAVGIKQPIVPGLLPILNGEQIKRITRMCGSSIPTELLRKLTQAGDD
RKKVHEIGIRHTVAQAQDLLAHGVAGIHFYVLNQYFHIAEIMEQIQPSLQHSTVKKY
>A0A4Z0W9C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronospirillum operosum|TrEMBL
MNPKTPISFEFFPPKTEEGLAKLDKVHDALSERHPEFFSVTYGAGGSTQERTINTVLGLH
AKGIPTAPHLSCIGSTADTLHYLLQRYKAHGVKRIVTLRGDLPSGMGGSTGGDFRYASDL
VAFIREHYGDAFHLEVAAYPEMHPQAASLDADIRNFVHKAEQGADSAITQYFYNAEAYFH
FVEKVRALGCNIPIVPGIMPITNYSKLARFSDSCGAEIPRWMRRQLEAYADDADSIRAFG
LDVVSRLCEDLLSNGAPGLHFYSMNQAEINLQLCDRLNIH
>A0A285CJJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus oleivorans|TrEMBL
MSLVEDLKSKVLIADGAMGTLLYSHGIDRCIDELNISKPDEVLKVHQAYLKAGAQVIQTN
TYGANYQKLARYGLEDQVKEINQAAVRIAKEATNLNQNAYVLGTIGGIRGIKKSVASLGE
IKRSFREQLFWLLQSEVDGILLETYYDFEEICTVLQIARHETNIPIIAQVSLHEVGYLQN
GMELSDALFQLEKLGADVVGMNCRLGPHHTIRSLETVPLPQKAFLSAYPNASLPQYVDGE
YTYGGDDDYFEKSALALYKEGVRLIGGCCGTTPRHIAAFARAVKDKAPVLEKVLPERKVQ
VQLKSSGSSTKHVYKKAKTTRSIIVELDPPRHLDTTVFFAGAKALKEAGIDALTMADNSL
ATPRISNIALASRIKNDIGVPPLVHIACRDRNLIGIESHLMGLHSLGITDLLAVTGDPAK
IGDFPGASSVYDLNSFDLIKLIKQFNEGLSSSGKQLKGKTDFSVAGAFNPNVRNLDRAVQ
RLEKKLAAGADYFISQPVYSEEKMVEIYESVKGLDVPIYIGVMPLTGARNAEFLHNEVPG
ITLSEQILTRMSACGTDKLKATQEGMAIAKHLIDAAFDLFNGIYLITPFLRYDMTVELTK
YIHDKEAQRKERKVFNG
>A0A8J7N7Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mangrovicoccus sp|TrEMBL
MSAPRISFEFFPPKSLDASFRLWETVQALRHLNPSFVSVTYGAGGTTRKLTHEAVETIHR
HYGLNVAAHLTCVDASRDETLEIARAYAAAGVTEIVALRGDPPKGAGRFSPHPDGFRDSA
ELVAALAETGLFKLRVGAYPDRHPEAADDGADIRWLKHKMDAGAHSAITQFFFEPETFLR
FRDRAAAAGIAAPIIPGVLPIENWKGVRKFAEGCGTIVPDAIAAAFEAAQADGTAEALAH
RLCVEMCRRLLDEGVEDLHFYTLNKPHLTEAVCRDLGIVPDAGLVRVA
>A0A445EU28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachis hypogaea|TrEMBL
MNVTVFMIPADIFAALEPIKDNEEAVKSYGIHLGTEMCKKILAHGIKTLHMYTLNMEKSA
LAILMNLGLIEETKINRSLPWRRPANVFRVREDVRPIFWANRPKSYISRTIGWDQYPHGR
WGDSRNPSYGALTDYQFMRPRARDKKLVEEWVVPLRSIEDIYERFKQYCLGKLRSNPWSE
LDGLQPETRIINEQLEKINLKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFF
CSKEKLDALVEKCKNRSSLTFMAVNKEGSWRSNVGQTDVNAVTWGVFPAKEIIQPTIVDP
VSFMVWKDEAFEIWSRGWACLYPEGDASRKLVEEVGNSYFLVSLVDNDYVNGDLFAVFAD
F
>A0A6L9EIE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poritiphilus flavus|TrEMBL
MKVTDHIKNAKGETLFSFEIIPPVKGKSIQELYDNIEPLMEFNPPFIDVTTSREEYVYID
RGGLLDKKLTRMRPGTVGICASIKHKYDVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNI
MALRGDAMREEQYFEPTKGGHAYASDLICQIRNLNNGQYLHEVIETDNCSDFCIGVAGYP
EKHMEAPSLKTDLKWLKHKIDLGADYVVTQMFFDNQKYFAFVEAAREMGINVPIIPGIKP
IAVKRHMQLLPQVFRTDLPEALIEAVEACKDNKEVRQVGIEWAIAQSKELKEAGVPVLHY
YSMGKSDNIKKIAKAVF
>A0A1H3B3B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria halocynthiae|TrEMBL
MSTFDTTQIAPTGHIPTPDGCVSHSRLERVLKSGRFAVTAELNPPDSADPDDVFQAAQPL
GEVADAINATDASGANCHMSSIGICALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAALG
VSNVLCLTGDGVGVGDQPGAKPVFDFDSLTLLRTIRTMRDEGKFLSGRKITRPPQLFLGA
AENPCIPPYDWRPDRLAKKIEAGAEYIQTNYIYDVPLFEKFMSRIRDLGLDKRVYIIAGV
GPLASARAARWMRNNVPGIHIPEAVIDRMERAQNPSEEGKKICIELIQQMSEIAGVSGVH
IMAYRREHLVSEIILESGVLRGRSGSASGN
>A0A562UFI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter frigoritolerans|TrEMBL
MKITEHISNAKGKTLFSFELIPPLKGQSIQGIYDAIDPLMEFKPPFIDVTSLREDFIYKE
HSNGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLQFLGIEN
VLVLRGDARRGDASFVPTPNGHNYATDLLQQVVNLNNGIYLHESNDEILKTSFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGANFIVTQMFFDNQKYIDFVNSCRANGINVPIIPGLK
PVVNSKQLVNLSKTFHIDMPEDLCDAVNSCKSEKEVREVGIEWTINQCKELIKFGAPVLH
FYTMSNAGPTKKIAEAIF
>A0A0F7PEE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea sp. IMCC20628|TrEMBL
MSISPRASAQDASDRIKVSFEFFPPKNGDMESQLWDSITKLATFQPDFVSVTYGAGGSTK
QPTMNTITRMCQETALAPAAHLTCVGSDKASVDAVAREFQAVGVNHFVALRGDPPEGVGA
AYQPHPQGYANGAELVAGLRGIADFEVSVSAYPERHPESPDFATDIDMLKRKVDAGATRA
ITQFFFDNDTYERYVERVRRAGIYIPIVPGILPIHNFGQVARFSKLCGASIPDWLARRFD
GLEKDPETRSLVAAAMAAEQVNDLVERGIDDFHFYTMNRAQLVYAICHMLGLRGAEAVGA
AA
>H5V452|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atlantibacter hermannii NBRC 105704|TrEMBL
MSFFHANQREALNQSLAEVAGRINVSFEFFPPRTSEMEQTLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWENGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFS
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A5F2DD06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira levettii|TrEMBL
MIQILLEVVPRDLSVVIQEVDFVKNKFKQITGINIPDLLRFENRSWDVASVVRPVFPNVI
PHIRAIDFDLDNCEPLVKTLQVLQIASVVVIKGDPPTDMSKQVYPTTSVKLIKKLKKEIQ
HLKVYAAIDQYRVGIKDEFDYIEMKKDAGADGFLTQPFFDMRLVDIFSEKLRGTEVYIGV
SPVVTEKSQSYWESRNRAYFPKEFRPSLEWNVKFAKDVLTYCSENGMNAYLMPIRINLEE
YLQQIFD
>A0A1I8EEC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wuchereria bancrofti|TrEMBL
MDAVRDDNEGDMSPTSSTDGFVVSSSGSTSDVVIPQACSKKWGESRTDWVANGTYVPLRD
RIKKRVAKGIPFFSLEFFPPKTTNSVANFFARLDRFREGNPMFVDIAWHFGSDPGNISSE
TSSSSVAAGCLDYCGMDTMLHITCCPYTKEQSIRHLEQSKALGLKNILALRGDLPRQDEN
PVLYKYRALDLIRWIKEEYNDYFTIACSGYPAGHPEAPSYRADLLYLKAKVDAGADFIIS
QIIFDGEVFQNFLRDCREIGITVPIIPGILPIQSYESIRRIAELSQLVIPDSILTSLEPI
KNDDDAVRNFGIWHAVTLCRTLFSNGSATSIHLFTLNREASSREILQQLGLWPRSPMRAL
PWRLFGENHPVRCKEDVRPIFWSMRPKSYVFRTREWDEFPNGRWGNSSSPAFNDLKDYYL
FYLKGQPTRDEQLRMYGERLETLADIQKVFVNFITQNINENGVKVSQLPWNEQHDGIRAE
TSLIKDQLLWCNSNGFLTINSQPSINGAPSTDPFVGWGKPGGYCYQKAYLEFFTSQANAE
VLWNLLPSYSRLNCHIVNHDATIDWTNTETTMPIAVTWGVFPGSEIAQPTVVDPLSFRVW
KDEAFSAWLNWSSIYAEGTSSRCLLEKIYNEYCLVTLVDNDYPKSTIIFDCLAQLVNR
>A0A4V2GAV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microterricola gilva|TrEMBL
MTAAYHHATPVIGGHRGALTPVSFELFPPRTDAAALALGRTIDRLAEANPAFLSVTYGAG
GSSRERSLTVLRYILEHTTVDAMAHLTCVGSSYQEANSLVRQFLDAGITSFLALRGDPPT
GVTGPAELGDLGSASELVQLIHRVQEEREPFSQERVPGAPQGTRIARRRRPERVAVAAFP
NGHPRARGTNADIDSLLAKQVAGATLAITQLFFHADDYLGFVDKARTAGVTIDIVPGLMP
ATSPRRLARIAELTGEEVPAELAIALEVEPDEQGQHEIGVGYIARVAAEVLAGGAPGLHL
YTFNQHRAVLGVLEQLGRMPVGAGSSR
>A0A5F2KNS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis|TrEMBL
MGLLEDLQKQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETSLPIMLNVSMHEQGVLQDGTP
LSEALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITDKEVKTRPKEFIS
VQDERTEPGLNEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPVYIGIMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIYLH
>A0A0B9ATB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium linens|TrEMBL
MSSTIVTPRLSASAPDNAPDRLPVGRRRLRRALSFEVIPPRSEAQAARMPGLLRFLDSLG
SDYLAVTSSATSNWLQGTADFIAEVTATTSLRPLAHLACTAGTEAELLTWIDHLLGVGVR
GFLAIRGDYPAGQQTLPAGHLPHADALVSLLRRIENDNVACLAAGRLGIGVAAYPSGHPE
SSGSEEDLDVLAAKQRNGADFAITQLFFDPTAYSRLRRRAEHAGIIIPIIPGILPITDPR
RLHTMSRLSGLPVPDGLLARFDGISDPASARRIGLDITAEHTAAILEHDADGLHFYTFND
QNTTEDLLTALDQKGISVSSFPPQPPPRRWPPSTDHTTTKENHA
>A0A7G5ILV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sandaracinobacter sp. M6|TrEMBL
MTLSLAAMGEAARAVNAPLFADVPGDIAVSFEFFPPKTEAMAATLWASVETLAPLRPRFV
SVTYGAGGSTRERTHGTVERIARTTAIPVAAHLTCVNATRGEIDAVADQYWEAGVRHVVA
LRGDPPGGQARFSPTEDGYRDAAELTAGLVARHPFEVSVGAYPEVHPEAANATSDLAHLK
RKLDAGATRAITQFFFEPETFFRFRDRAAAAGITAELTPGIMPVVNYASLVRMAGMVGTS
IPAWLGRLFDGLDAHPEARQLVAATIAAEMVRRLYAGGVRHFHFYTLNRAELAFAICHLL
GVRADSIENQVAA
>A0A6G1U1F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLQNEGNKRGFSFEVLPPLKGNGTATLFRTIDSLKDYAPRFINITTHHSEYVYKE
LENGLLSRQRVRRRPGTVAIAAAIQNKYDIPVIPHVICSGVSKEDIEYELLDLQFLGISN
ILVLRGDKAKDDRVFTPTLNGHANATDLLKQVNQFNEGFFCDGTPIKHPGEKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQKLGAAYAVTQLFYDNQKFYDFVDKARKIGITIPIIPALK
PFAKLSQLTVVPKTFHCDIPEDLAQEVLKCKTDEDAKALGIEWTTAQVKDLFEHGYNNIH
FFTVSAVESVKQIAKTLF
>A0A2S7BBA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. populi|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDT
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGDAPALHFYTLNLAKPTTQVLQLLGR
>A0A5B8S2V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium ginsenosidimutans|TrEMBL
MNQASETRRAHASPLFAGLPGDIGVSFEFFPPKTEKMEETLWDSVLTLAPLSPRFVSVTY
GAGGTTRERTHNTVARIVRETGIPAAAHLTCVEATKDEIAEVADAYWQAGVRHIVALRGD
PPGGDAKFTPHPQGYANAVELVAGLREMHPFELSVSAYPETHPDAASPAADLDNLKRKLD
AGASRAITQFFFEPDTFFRFQDACLAAGIEAEIVPGIMPVSNFAAIQRMSGMTGTAVPDW
LGHLFEGLDEKPAARQLVAATVAAEFCRRLYAGGVRNFHFYTLNRAELSYAICHLLGLRP
EHAA
>A0A2W4Z8U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas hengshuiensis|TrEMBL
MTPTISDLEEARRALDAPLFADLAGDCAVSFEFFPPKTEKMESALWDTVRALEPLGPKFV
SVTYGAGGSTRERTHATVARIARETSMPAAAHLTCVEAGRAEIDEVAQEYWAAGVRHIVA
LRGDPPTMGQKFVAHPDGYENAAALVAGLQRLHPFEISVAAYPECHPDSAHQAADLDNLR
AKMDAGATRAITQFFFTPEAFFRFRDAAAAAGITADLVPGILPVTNVAQVRKFAGLCGAS
IPAWMDRLFEGLDDHPGARALVAATVAAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLM
GLRPKATPVAAAA
>Q87L52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDATRSELIEIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRVAVEA
>A0A1Z8P3U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium TMED23|TrEMBL
MDKNHNVAKESNLATRLNSNQFAITAEITPPISVDPSDVLKKIMPLKDIVDAINVTDGPN
ANVHMSSLAASAIMQRSGIEPIVQITCRDRNRIALISDLLGISALEIKNILILTGDNPTS
GDQPTAKPVFDLKSHELIKIASQMATEGTIPSQNTKTPNIKSISKKANFIIGAADVPTDK
YVEKWSNSLKKKQQSGANFIQTQLCYDMQIIRSYAKLLIEEGYTRDMFFLIGNGPLGSVK
SATWMKDNLWGVKIPNNILNRLDNAKDSEEEGIKICIEQMEEISQIEGISGVHLMAPLNA
KSIPVAISEANVLKRD
>A0A7W5ZQH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Runella defluvii|TrEMBL
MTKITDYIQQANGKTLFSIEVIPPVKGNNINELLGNIEPLMDFKPPFIDVTYHREEYIEK
PLADGRIQQIVTRKRPGTIGICASIMHRFGVDAVPHVLCGGFTKDETEDFLMDLHYLGID
NVLVLRGDPAKPYKTFKPKTNGHAYASELVEQVVNMNKGQYLHEEVEPLAPTGFCIGVAA
YPEKHFEAVDFDTDFDYLKQKVALGADYIVTQMFFDNSKYFDFVQKCRAVGVNVPIIPGL
KPLSTKKQLGILPKIFYLHMPQDLVKAVEGCENDAQAKQVGIEWCTQQCRELMDFGVPVL
HFYTMGKSDNIYKIASNLF
>A0A8F8X2X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. USK10|TrEMBL
MTRTPSIVDRIRSSGDGRVPFSVEFSPPRDEAAEARLWRAVREFERMGPAFVSMTYGAGG
STRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRGISNILVLRGDPPGD
PLGEWEKHPQGVEYAEDLVRLVRDLGDFHVGVASFPEGHYRAPDLAHDTRYLVSKLRAGA
EYSITQMFFDVDDYLRLRDRVSAYDAEQGAKPIIPEIMPITSLGSVRRMLELSGSSLPAH
LEKRLATAAGDGPEENRAAVREIGIDLATEMSERLIAEGAPGLHFITLNFARATSEVLAR
LGDKVGSGVADPSPVTPAPVS
>A0A850HB57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea phocaeensis|TrEMBL
MKIRDLLKDSNPHISFEVFPPKTDAAYESVMKATEEIAALKPSFVSVTYGAGGGTSKNTV
KIASHLSNDLGVTSLAHLTCVSSTKEEVHRVIEELKEQKIENILALRGDVPADGEFPLPN
HYRYASELIEDIKRQGDFCIGAACYPEGHTETEHKKDDIQNLKHKVDCGVDFLTTQMFFD
NNILYNFLYRIREKGITVPVLPGIMPVTNGKQMKRICALSGTVLPERFRAVVDRFGDDPK
AMQQAGIAYATDQIIDLIANGINHIHIYSMNKPEIAAAIIRNLSEIVKP
>A0A1Y1VWB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Basidiobolus meristosporus CBS 931.73|TrEMBL
MKVTSRIQQALEEKRPFWSFEYFPPKTDEGVENLFERIQRMSGLNPEFIDVTWGAGGSTS
DRTLEICTTAQAYQNLETCMHLTCTNMTKSKIDFALKEAKAAGIQNILALRGDPPRNHEY
ANECETQFRYAFDLVSYIRQEHGDYFCIGVAGYPEGQPESESKEKDLEYLKLKVDAGSDF
VMSQIFFDPRLFLRFVEDCRAIGITVPILPGIMPIQTYTSFRRLTNLCQIEVPTQILETL
ESIKHDDQAVKEYGVKLCIEMIQELRKGGVNGFHFCTLNLERSVRLILEGCGFVSKQLTK
IDGLPKQENGHTAPIQPTVLEGIIMQNESWDEFPNGRWGDSRSPAYGEMDGYGASLKVTM
QEAIALWGYPVDNDDISALFSKYIQGQLKALPWSDEPLFAETNAIGEKLADLNSKGYWTV
GSQPAVNGVRSNDPVFGWGPKNGYIYQKAFLEFFTSPEKLAELLAKAASNPFITFYAQNT
KGDFKTNVELEEPNAVTWGVFPSREIAQPTVIERGSFEAWAEEAFQIWNEWKMIYPPQSP
SAKLIQEIGDTYYLVNIVHNDFQNADAIFALFQ
>L7LGK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sihwensis NBRC 108236|TrEMBL
MTDPISTDSDVRARPGQSVVERLADPHSGPVPFSVEFFPPRDAAEEARLWRAVRIFERMN
PAFVSMTYGAGGSTRDRTVRIAGELATETTLLTVAHLTAVNHSVDELRGLVGAYADKGIV
NLLALRGDPPGDPLGEWVKHPEGVAYAEELVRLIGELGDFHVGVASFPEGHHRAPNLAAD
TGNLVRKLRAGAEYSVTQMFFDVDDFLRLRDRIAAADPEQGAKPLIPGMMPITSLASARR
MTELSGSKIPPAVEERLAKAAGDGPEENRADVRAVGIDLCTEASLRLISEGVPCLHFCSL
NFAKATSEVLERIGIDTRGALAGV
>A0A2K9PSR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavivirga eckloniae|TrEMBL
MKVTNHIKKAKGKTLFSFEIIPPQKGRSIQELYNNIDPLMEFNPPFIDVTTSREQYIYID
KGDGLLDRKITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMSHQKYFEPSKGGNHYATDLVAQIQNLNCGKYLHDVVESDHKSDFCIGVAGY
PEKHMEAPSLQADLRRLKEKVNAGADYVVTQMFFDNEKYFEFVEKAKEAGINVPIIPGIK
PLAVKRHLQILPQVFKIDLPETLVNEVEKCKDNKQVRQVGVEWAIKQSEELKKAGVPVLH
YYSMGKSDNIKAIASKLF
>A0A1Q9T2C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serinicoccus sp. CUA-874|TrEMBL
MGNTYPSVVLERLLRGARLEILPTAAVADQVHGHVEPGRTLTVTASPAKGLEATLQLAEQ
LVGAYHVVPHLAARMVERAALPDLVARLTEAGITEIFVPGGDAEPTDQTFTSALDLLIEL
DSLGSPFTGVGITGYPESHPGIDDDVIVQSMWDKRRYATAVVSNMTFDDDRVGQWLERVR
RRGVELPVWVGVPGPVDPARLLRMASTIGVGDSMRFLRKQRNVFTRMVMPGFSTTRFAHR
MAVLGTADRLGIAGLHLYTFNQVAQTEAWRRTQLSKVAELRDPASGP
>A0A0M2QZX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiloniella litopenaei|TrEMBL
MSTEFNPEVVKQQIIDFMTGFTIETTPGSAAKTPDYRVHLRPGTEIAVTFLPGSDFADTV
STSKRLKEEGFAPLPHFAARSIRSQSDFEEYLKTLQGEVGIEHAVALGGAVDKPLGEFES
SMQLMETGLFDKYGIKSIGVAGHPEGSPDISEAGLREAIAWKNAYKEQTDAYMYIATQFC
FEAEPIIAWDKKIQAEGNKLPIHLGVPGLATLKTLMNHAKACGIGSSMRVLTRQAKNIAK
LMTVNAPDKLVMDLARYHAEDPSCGIKKVHMYPLGGMKKSAAWSYAVTDGDFTIDPKGKG
FKVNRDIG
>A0A4Q4SDH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria tenuissima|TrEMBL
MERITDKINALPDGANYFSLEFFPPKTAMGFSNLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCIGVAAYPEGHSDQSHPQHQDPQFDL
PSLIEKTKAGADFIMTQLFYDVEAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTTLSHAKLPSDMLARLDAVKSDDELVKQEGVKIMDEMVEHIKARPDTCRRGFHFYTLNL
EKAVSHIVEDTHLIPSTIDDNDDVIVETTPAINLEPPPNGFVPHRRRSSAVNSGPRNRVI
ISHSSAAKSSNYSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKDDISKLFRRHIEGDLEAIPWSEQSLSP
ETLTISKQLLALNAKGWWTVASQPAVNGVKSTDPVFGWGPKNGYVFQKPFVEFFIPASEF
AALKPKLDAHEQVTYFAGNAAGEFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIFQEWQRIYPPRSASSTLLGALRRDYWLVNVIWGDFVQGEGLWEFLEQ
>A0A1E4KZU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium SCN 69-48|TrEMBL
MLPTSFEFYPPKTDEQHAQFDRTVRKLKAHAPQFMSVTFGAGGSTLSHTPETVQRLRGEH
GVDGVPHLTCVGGSREEIRALLKLYRALGCTRIVALRGDLPSGMARSGDLRYASELVRLI
RDEHGDHFHVEVAAYPETHPQAEDAGIGLGHFKTKVDAGASGAITQYFYNADAYFRFVDD
ARAQGIDLPIVPGIMPIANFSQLRRFSEACGAQIPRWIDQRMRAFGDDAGAVREFASDVV
AGLCRRLAEGGAPALHFYTLNLAKPTQAVLQRLA
>A0A3A8W6S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium D16-59|TrEMBL
MDIREYLEKKPLLFDGAMGTYLAKKYQELDTEPCEMMNLLHPELVLEVHKEYIKAGAVAV
KTNTFSANCEMLKEDRAVVEEVIREGFRLARRTASEAGREVFVFADIGPVPEHEGVDASA
AYREIADVFLACHAECFLFETMADSEAAEACAAYIKERSPEAFVMVSFAASPEGYTRGGF
LAKKLFWGMQQSEAVDAVGFNCISGPKHLLELVKKLPKEQVKKYLTVMPNAGYPTMVGNR
IYYGTDRRYFGQAAYDLLQEGVSIVGGCCGTTPEDIAQVQEKIQVCEKEWAERRENGQKT
ESPGKGKVLAKGQEGTQESQMAGGKNIADAMENPGNSFAEKLRQGKKVLVVELDPPVEPD
IDFFMEGAARYQLAGVDAIDIADCPVAKARIDSSILACKVSRELGLTAIPHMTCRDRNIN
ATKALLLGLNMEGVNNVLAVTGDPVPTELRNQVKTVFGYNSAVLARHIQSFNEEIFCENP
FMVSGALNINALNFDFQLSHAKSKIENGMSVLFTQPVLSERGFENLKRARKELDVKLLGG
IMPVVSYRNAAFMNSEMAGIEVTPEIMEQYRGKNREEGEELAFKISAGVIREISEYIDGY
YLITPFKRVELVLRIISYIRNC
>A0A7L1I7E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nycticryphes semicollaris|TrEMBL
MVNETQHTCSASSSSKSDCGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRAETFLR
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A850GI08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudenhygromyxa sp. WMMC2535|TrEMBL
MLIRDRLAHKRPVYSFEFFPSKDEAGERALWRSLAHLSRLRPDFISVTYGAGGSTRARTI
ELVGRIKRELDIEPMAHLTCVGSTRDELAEVIDGLSEQGVQNILALRGDPPRGEKTFEPT
PGGFRYASELIAWMRERWPQLCIGAACYPEVHPEASSPEDDLANVKRKVEAGADFLITQL
FFDNATFFEFCDKLRGVGVNVPVLAGIMPVTNIKQIQRFTKMCGATIPQVLHDRLDELGA
EGRPDPHEVFWTGVSYAAHQCRELLVHPNPGPFAGRGELGVAGLHFYTLNRSPATRALFE
MLHLSAPMR
>A0A218ZLV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cuniculiplasma sp. C_DKE|TrEMBL
MIQNRESFRETLRSVPLIFTVVPLRDSKTGDPEHDNRIVKNIESRIMEISHTLSDFPKLT
AVNVPELVEENHEGKPRYNSIYTRKLAKGIADGIGREAIINKVVAHMESYDEFANWIIET
ESQGIRNIVLVGGNTRHHRYTGPNVSEANLIARHLMKIKELDDLTIGNICLPERSGEARR
MLYKTISGADFFTTQMLFESDHITHLLKEYSELCKKAEVSPATVILSFAPLKSVADLNLL
DFLGVDLPDETKDYILENEQVSRVYKRSIKNALDVLQVIVKDRKENYPEISIGINVEQLT
KSNMPYSIEMLREFHSMIEKK
>A0A7G6Y0C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. NBWT7|TrEMBL
MTLSINQLEEARRALDAPLYADVAGDIEVSFEFFPPKSEKMEATLWDSIATLAPLGPRFV
SVTYGAGGSTRERTHATVARIARETDIPAAAHLTCVEATRAEIDAVANEYWAAGVRHIVA
LRGDPPRAGERYAAHPGGYENAAALVEGLRRLHPFEISVACYPESHPDSGDPAADLDNLK
RKMDAGATRAISQFFFSPDTFFRYRDAVAAAGIDAEIVPGIMPVTNFAAVTRMSKMCGTD
VPAWMERLFAGLDDLPEARQLVAATLTAELCRKLYAGGVKQFHFYTLNRAELSFAICHLL
GVRARPAARAEAA
>A0A1E4LYW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium SCN 68-20|TrEMBL
MSLPISFEFFPPKTPEGAEKLRAVRQQLYALRPQFCSVTYGAGGSTQEGTFATVRAILAE
GADAASHFSCIGATRASVRAQLAELKAMGVKRLVALRGDLPSGYGMGGEFQYASDLVAFI
RAETGRDFHIEVAAYPEVHPQARSPEADLQAFAAKVRAGADSAITQYFFNADAYSRFVED
ARRLGLDVPVVPGIMPIMGSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIRAFGMDVV
AQLCEQLRRAGAPGLHFYTMNQSAATQALCQRLGLIG
>A0A090EGM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. SOD10|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDAVIREFADMGVKRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A380ZBH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides eggerthii|TrEMBL
MHKRIACPSGHFSFLFRIFVPNVQGFCQLDKDNEEEMRVIDLINSNEKTAFSFEILPPLK
GTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDLGNGLFQRNRLRRRPGTVSVAAAIQ
NKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDLLVLRGDKAKHESAFTPESNGYLHA
IELQDQINQFNKGIFVDGSEMTVTNTPFSYGVACYPEKHEEAPNIDTDIYWLKKKMENGA
EYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKPFKKLSQLSMIPKTFKVDLPEELTK
EVLKCKNDAEAQQVGIEWCVQQCKELMKHHIPSIHFYSIGAVNSIKEVARQIY
>A0A2D8RED6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hahellaceae bacterium|TrEMBL
MQSQQKFKPRYSFEFFPPKTDEGWKKLQKERDELAKRKPDFFSVTYGAGGSTRERTIDTV
LQLHRQGISTAPHLSCIGSTKEAMDDLLTLYKNEGIQRIVALRGDLPSGMGSSGAFRYAS
DLVRHIREHSGQHFLIEVAAYPEFHPQGPSASKDFDFFKQKVECGANSAITQYFYNIDAY
FSFIDECEKQGIDIPVVPGIMPITNYSKLARFSDMCGAEIPRWIRWKLEGYGDDSESIVK
FGEEVVSKLCERLIQAGAPGLHFYTLNQAAPSLAIWDNLGLKSPIEF
>I2GHB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrisoma limi BUZ 3|TrEMBL
MTKITDHIRNANGKPIFSIEVIPPVKGDTLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHKFGVDPVPHVLCGGFTREETEDFLIDLHYLGID
NVLVLRGDPAKPFNTFKPKENGYSYASELVEQVANMNKGVYLHEEDTALSPSDFCVGVAG
YPEKHFEAADHEIDFQYLKQKIDKGADYIVTQMFFDNQKYFTFVEKCRQAGINVPIIPGL
KPLSTRKQLQVLPRIFHLQMPQDLVTAVEVCENDQQARQVGIEWCIQQCRELIAAGAPVL
HFYTMGKADNIAKIAKEVF
>A0A3A5RFB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AM41-16|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A084ZU30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trabulsiella guamensis ATCC 49490|TrEMBL
MSFFHANQREALNQSLAELHGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNYKQLTKFATMTNVRVPKWMDAMFE
GLDDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPNV
>A0A6F9D8S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phallusia mammillata|TrEMBL
MGPGNNDVSKFSNDSDNLSERIKSRIASRDNFFSLEFFPPRTEQGASNLIGRLDRMGGGG
PLFIDITWHPAGDPGGDKITSSTKIAGTVLTYCGLETMLHMTCINQSTDTMLKHLEKTKN
LGIRNILALRGDCEDENRPLNDDGFNYGVDLVKFIRKHYGQYFTICVAGYPNGHPDNPSY
KNDLHYLKEKVDAGADFIITQLFFKANDFLQFVDDCRDIGIVCPIIPGIFPIQTNRSLVQ
LTKLSKLDIPEEVANVIEPIKENDAAIRKFGIDFATDMCRTLLNSGKVHGLHMYTLNLET
ATAQILKNLGLWCTEVARPLPWRASGKLERKSHEEIRPIFWVDRPKSYIHRTQEWDEFPN
GRWGDSASPAFGELKNYHLFFLRSRTPVSKLKQQWGEKLNSEEDVFHVFEHFINGKKNQN
GVKVTETPWSDDGLSAETALLSETLAKYNSLGVLTINSQPNVNGVPSTHPIFGWGDKGGY
IYQKAYLEFFVNETNAQALKQVLSEYEPRVLYHIINRCGEEDYTNADRKVPNAVTWGIFS
GKEVIQPTVVDPVSFKVWKDEAFALWLEKWAKLYDDKSHSREIIEDIASNYYLVNLVDND
YPSENILWEVLDKMLHIAQTSRDKNENVITHVAEKSLNGHGHVNDKIVA
>A0A7K5XY49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dromas ardeola|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAIDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A0D8FTE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrimicrobium acidiphilum DSM 19497|TrEMBL
MRKVELLPAHQGLVRSVEVWPARNEAQSDRLSALLTAMKTVQPDFITVTYGAMGSSRERT
LTLIEDLIEEGFAVVAHLACLGHSRSELVDLIHRYQTLGVRGILALRGDPPLDGVVEFAA
SELHYANELVELVRQESDLPVAVALHPDGHPDSTDTASDIQYAAQKLEHADLGLTQFFFE
YASFAGLREAMLGQGVKVPIVPGLMVPATHKQLMKMSQIAGLDPPTSFDGVALSGDGDTS
AFQSLALDAAVALAKRAIADGVRGIHLFSMNNARVTTEFFARLQVTASA
>A0A249E103|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Portiera aleyrodidarum MED|TrEMBL
MKKNEVEISFEMFPQKEHYKTKVFIKKIKQLYKKKDIKFCSITYGAGGSNKKNTLEIIKN
IKKQKIECVPHLACITTKEKDLIKTLKSYKKIGIKKILALRGDIKTNTKTKFINSLDLLT
LIKKNFYKNFEVIVTAYPEMHPNTISFEKEVCFVIKKFMFGANKAITQYFYDPDSYFYFV
EKVRKYGVEKHIIPGIMPISNVNNLINFSKKCGANIPKWIYKKLEFCKTDNDIEHIGNDI
VIKLCETLIKGGAPGLHFYTLNKLEPTLNILNSLIT
>A0A451CXB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MINIIKCNNEKYNYESYHLKNKIRISFEVFPPKDVILTKQLFHSVQKLNKCNPDFFSVTN
SIYSKNRDETFLIVKKIRSLTNKTVFAHFTTIGYDESDIKAIAMKYWNHGIKNIIALRGD
LPVQYTKKIIYASNLIKLLKSINNFEILVAAYPELHPESNSLKDDLNNLKYKVDLGITQA
ITQFFFSIDKFLKFRDNCKSMGLAISLIPGILPILNINQLQKFANMTNVYIPRWIFDSFH
EYEGDYDKCTTLSVNIAVNLIVRLYHEGVKNFHLYTLNQSHLSWKICYQLGLI
>A0A5D0MTC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flexistipes sinusarabici|TrEMBL
MKISDILSGKKRVLSFEFFPPKKVENEHILFESIERLKGWNPDFISVTYGAGGSTRDKTL
DWTKKIKDDYLLNVMMHLTCIASTEERVVSILKELKKNGIDNIFALRGDIPEDLDNKEEA
FKDFRYASDLVRLIREVDDSFSIGVAGYPEGHIECPNIGEDIENLKKKIDQGADFIITQL
FFDNRYFYDYLDMLEKYRITLPVIAGIMPIINIKQVIKFTDMCGATVPKYLKNKMMDRSP
EEMLNVGVDFATEQCRDLIENNVKGLHFYTLNRSKATINVLNNLNLD
>A0A5C4S2Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobaculum thiosulfatiphilum|TrEMBL
MLVKEILDARTEPVFSLEFFPPKKQEDWDKLFATITNLNPLEPSYVSVTYGAGGSTRERT
HNLVTKIQQETGLTVVSHLTCIGAEKSEIESVLKLYREHGIKNVLALRGDKPADIPTLEE
AIKDFPHAIDLVRFIRENFPEMGIGVAGFPEGHPETPNRMKELEFLKEKVDAGADYIVTQ
LFFDNRDYFDYVERCDLAGITVPIIPGIMPIMSKKGMIRMGELALGSRIPSKLLRKVLEA
SDDKEVAEIGIEWATNQVQELLDHKVKGIHFYTLNLSEATLKIFRNLKRG
>A0A4R1UK22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. PhB165|TrEMBL
MTSVQRPAGQRPNLAPAFGCLPGDISVSFEFFPPKTEKMDEQLWDAITQLAPLTPSFVSV
TYGAGGSTRERTHATVARLVRETSLVPAAHLTCVGASKGKIDEIADQYWEAGVRHIVALR
GDPPPSQGGVFTPHPEGYASAADLVAGLKARHDFDISVAAYPEVHPEATSAQSDLDNLKR
KIDAGANRAITQFFFSADAYFRFLDKTQAAGIDAPILPGIMPVTSFAAIRRMSGNTEIPV
WLEAMFEGLDERPGPRALVAAVAAADLCRGLYEGGVRDFHFYTLNRAEQTYAICQLLGLR
PQS
>A0A0Q5QZN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia sp. Leaf354|TrEMBL
MKRQTWCEAGTGEPLFFAITPPRKTVSAERAKEIAAATIGRLTAISPDALVVYDIADESA
RNPDKRPFPFSPTMDASEFVTQHLHGWTGRKIIYRAVGKYTEDSLGAWLTQQNPDEVSSV
FVGASNADQVGATSLRRAYTLRDERRPELTLGGVAIPERHTKDRCEHEKLIAKQESGCSF
FITQIIYDVNAAKNLLSDYRLECRRRGIAPVPIVLTFSVAGSLTTLEFMRWLGISVPTWV
DNDVANSLDPLATSHAHALAAAADLADYCRRMRIPFGINIESVSARRAEIDSAMDLALRV
SDLLR
>A0A6A7SHC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|wastewater metagenome|TrEMBL
MNEAATTTTTAADAARACTALAAPRFELLPIKGVHERASALPAGATVTVTCSPRHGIERT
LDTAEGLAAAGFRVVPHVAARLIRDRHHLQAVLERMAAAGIDDCFVVGGDAERPAGPFPG
GVELLDTLAGASPRPARIGVPAYPEGHHRMDTRTLDAALSAKAANADYVVTQLCFESAPV
LAWLRRQRERGLTLPVLAGIPGVMDRRRLLSVAVRIGIGDSTRALGRQRGLVGRLIHSGE
YRGDDLVWGLVDGLGDPVQGLAGVHVYTFNEVAATRDWLTTLHDGLCQWHGLSAEAEVAA
GTAGVHAEQPG
>A0A7C3HSZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meiothermus ruber|TrEMBL
MKVSTLLQSGKPLFSFEFFPPKTPRGEAALFRTLHELKPLKPAFVSITYGAGGSERNKTA
EWAARIQNEVGLPAMAHLTCVGSTREELLARLHEYARAGVENIMALRGDPPQGAREFQPV
AGGFRYAAELVALIRAEFGDRFTVAGGAYPEGHIEAVSLEADLRHLKQKVEAGLDFVVTQ
LFFNNALYFGFVERARRIGIRVPIVPGLMPITDLAQVRRFMDLCGASIPGPLLSRLERAQ
SPEEVLEIGVEHTTRQAQELLEAGVPGLHLYTLNKSPATRRVMQNLQIVLR
>A0A1G3K2C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. RIFCSPHIGHO2_01_FULL_65_24|TrEMBL
MTTNLNSLAEAHRAAASPLFAGLAGDIGISFEFFPPKTDKMGETLWDSIRTLEPLGPRFV
SVTYGAGGSTRERTHATVARIVQETGIPAAAHLTCVDASRDEIAEVAQAYWDAGIRHIVA
LRGDPPVKGESFRAHPDGYGCAADLVSGLLEIAPFEISVAANPEMHPEALSPQADLDNLK
RKLDAGATRAMTQFFFEPDTFFRFRDAAAAAGITAPILPGIMPVSNFAAIQRMSAMCGTD
VPRWLASLFEGLDDLPAARQLVAATTAAELCRRLYAGGVRDFHFYTLNRAELSYAICHML
GVRPAAPATEKAA
>A0A0R2X474|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium BACL22 MAG-120619-bin32|TrEMBL
MKITEHIKNSNGKTLFSFEIIPPKKGNSIQELYDNIDPLMEFNPPFIDVTTSREEYLYIS
KENGLLERKITRMRPGTVGICAAIKHKYKVDPVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMSHQKYFEPIDGGHEYASDLVAQIHNLNTGKYLHDVQESIDKTDFCVGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYIVTQMFFDNKKYFEFVEVAKNMGIHVPIIPGIK
PLAVKRHLQLLPQVFRIDLPEVLISEVEKCTTNQQIKQVGIEWAIQQSKELLAAGVPVLH
YYSMGKSDNIREIASKLF
>A0A1R4GGS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gulosibacter sp. 10|TrEMBL
MTQEEARLAALLHDYSLEITGRDLDSIGEARAAIPAGSRINVTFLGSEEPELRLRTARAI
REAGFAPVPHLAARRLRSRDEYRGALAALQREGLSERLFLVGGDPATPLGPYADAHSLIA
AEPLAEYGVREVGIAGYPEGHPGIGADALREALLGKLAAIRGLGLEAVVATQFSFDAEAV
ARWVRSVRELGYEGPIRIGTPGPVGVKRLLRYASRFGVGSSAGIVRKYGFSLTGLMGTAG
PDRFLRALAAEPGLGDIAVHFYTFGSLAGTAAWARDAG
>A0A1Y1R932|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacteraceae bacterium 4484_4|TrEMBL
MFERLIKKLQDPKKSYITLETTPRHDATFMPIIETIDKLGIAEKVDGFSTTDNPLAKLKF
NSIIAAHQLQQHFKKPVLATMTMRDRNKIALQSDLLGANAIDVRAILALTGDPAKISDQP
NAKGVFESDSTMLLDIVKCFNAGIDYAGREFGIKPKPIYPFAVSNAFAKNPKTLLKRFVK
KLDHGALGIITQPVFDRENVLMLLELFEEAKASNSKGKNGTLILGLFPVTRLKTAQFLSS
HVPGIHVPKKWIDALYEAQKKGEKTEEKVGLELSMELYASIMEIHPKIHIMTANRFSLAK
KLLS
>A0A522J422|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp.|TrEMBL
MVPGSTSAKKTISLEFFPPRDIAAREKLVRTAKQLLALQPEYVSVTFGAGGSTRSGTIDT
VHIMQNLGLEVAPHLSCIGASRAMLREVLDTYRENGVRRIVALRGDVPSGMGGDQGELHY
ASELVRFIREYSAGWFQIEVAAYPEVHPQAHSTDADLDHFVAKIEAGADSAITQYFFNAD
AYFNFVERVRARGVTVPIVPGIMPITNHSQLVRFSEMCGAEVPRWIRRRLGEFGDDRASI
KAFGVEVIARMCQNLLDQGAPGLHFYTLNSAESIMAISKLLAR
>W9DFG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia alkanivorans CGMCC 6845|TrEMBL
MTPTAPAPSIVERLSAPHRGPVPFSVEFMPPRDAEGEARLWRAVRIFERLSPAFVSMTYG
AGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSIAELRALVGAYADQGIANILALRGDP
PGDPLGEWIAHPEGVEYAEELVHLIDTLGDFHVGVASFPEGHHRAPDLEHDTRNLVNKLR
AGAEYSITQMFFDVEDYLRLRDRVQAADPEQGAKPIIPGIMPVTSLASIKRMAELSGSVI
PPKVVERFTKAAGDGPEEDRATVRAVGIDFATETAERLIAEGAPCLHFCSLNFAKATSEV
LGRLGVDVDAALHVPA
>A0A2N0VV45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rahnella sp. AA|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLRPKFLSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELRQIAQDYWESGIRHIVALRGD
LPAGGGKPDMYATDLVQLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPHWMNSQFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEAAIPV
RA
>C9KZW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides finegoldii DSM 17565|TrEMBL
MKVIDLIHNNKKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELVKEALKCKTDAEAEQVGIEWCVTQCKELMSHGVPSIHF
YSIGAVDSIKKVAKIIY
>A0A7J8NKB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium lobatum|TrEMBL
MKVIDKIQSFSQEQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGIATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFINDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DALVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A7W4E0L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIEKANGKTLFSFEILPPLKGQNINLFFDAIDPLLEYSPSFINVTYHREEYEYVE
HENGLLERKVVRKRPGTVGICAAIQNRYHIDAIPHILCGGFNREETENFLIDLDFLEIDN
VMALRGDVMKSETYFKPEKNGNAHASDLVHQIKQMNNGIYLDHNIELPSPTNFCIGVAGY
PEKHMEAASLHQDIMNLKKKQEAGAEYVVTQMFFDNQKFFEFVDKCREEGITIPIIPGLK
PITAKSQLSMLPYRFKVDLPDDLVIEITKCKTAADIKQVGIEWCTAQSKELKERGVPALH
YYSMGRSEGVKQIVNEVF
>A0A7Y3A0F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIEKANGKTLFSFEILPPLKGQHIQSIFDNIDPLMEFNPPFIDVTYHREEYVYKE
MENGLLQKQLVRKRPGTVGICAAIQNKYEVDAIPHILCGGFTKEDTENFLIDLDFLGINN
VMALRGDPVKSEIYFKAEKEGHHYASELVTQIQQLNEGYYLDEALLNTNKTDFCVGVAGY
PEKHLEAPSLDSDIHFLKKKIKKGAAYIVTQMFFDNEKYFEFVEKCRASGITAPIIPGLK
PIATMKQLNLIPHRFNVDLPEELIKEVIKCTDNNQVSKVGIEWCIAQSKQLKAAGIPVLH
YYSMGRSDNIKAIATEVF
>A0A7W4EXL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIEKANGKTLFSFEILPPLKGQNINLFFDAIDPLLEYNPSFINVTYHREEYEYVE
HENGLLERRVVRKRPGTVGICAAIQNRYHIDAIPHILCGGFNREETENFLIDLDFLEIDN
VMALRGDVMKSETYFKPEKNGNTHASDLVHQIKQMNDGVYLDHNIELPSPTNFCIGVAGY
PEKHMEAASLHQDVLNLKKKQEAGADYVVTQMFFDNQKFFEFVDKCREEGITIPIIPGLK
PITAKSQLSMLPYRFKVDLPDDLVIEITKCKTAADIKQVGIEWCTAQSKELKERGVPALH
YYSMGRSEGVKQI
>A0A8F6G0L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulophaga sp. HaHa_2_1|TrEMBL
MKVTDHIKNANGNTLFSFEIVPPVKGNSIQELYANIEPLMEFNPPFIDVTTSREEYVYVD
KAGLYDKKITRMRPGTVGICASIKHKFDVDTIPHVICGGFTKAETEYMLIDCHYLGIDNV
MALRGDAMKEEKYFKPTEDGNCFASELVTQIQNLNQGRYLHDDVQGEDKSNFCIGVAGYP
EKHLEAPSFKSDLIRLKQKVDAGADYVVTQMFFDNQKYFQFVEAAREIGINVPIIPGIKP
IAVKRHLQLLPQIFSLDLPHDLVEAVEACKNNAAVRQVGVEWAIQQSKELKAAGIPVLHY
YSMGKSNNIKAIAKEVF
>A0A559JLD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella terricola|TrEMBL
MKPDLRAALSNRPLVGDGAMATYLYQLGLPVGVSFEEFNLLKPDVIAEVHRQYAAAGAEI
IETNTYSAQHNKLSRYGLEKKTEVINAAGVAIARNAVGPEAYVVGSIGAVRGGAGKNIRT
ATVKRDFEEQIGVLLASGVDGLILETFFDLEELSLALSIIRKKSDIAVICQFAVEDPSRT
RDGIPLPEAFRRLKAEGADVIGLNCRSGPAGILRALETIPKDIGLPLSVFPNAGIPDYVD
GHVVYSATPEYFGASALRFANAGARLIGGCCGTTPEHIAEISKALRDYMPPAQEEATKES
AHPAVEVAVEPTAAEAFDDGTPVITEPSIVDLVRERHTVIVELDPPRDLDIRKFMAGAQA
LKDAKADALTMADNSLAVTRMSNLALAALLKERVGIRPLAHIACRDRNLIGTQSHMMGFD
ALGIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKAKFVI
GAAFNPNVKHLDKAIQRLERKIAAGADYIMTQPVYDPVLIERIADMTKHLSIPIFLGIFP
LASGRNAEYLHNEVPGIQLSDSVLGRMSGLEGGAGRAEGVRIAEELLDVAMEHFNGIYLM
TPFLAYDMTVSLTEYVRSKSKTTSGV
>A7EWQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)|TrEMBL
MHIKDMLAEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHYIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVTIPVIPGIMPINTYASFLRRCNHMGCKIPPKWSASL
EAVKNDDSAVRNIGKDLVAEMCRRIIQAGVHHLHFYTMNLAQATRMVLEELNLTPSTQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLENGIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHDP
DLTYYAVKKTGDLQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIGRANFNKFGVQKGSQRSKMVWAGV
>A0A285HCX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes atraurantiacus|TrEMBL
MALGLPSRLPGTPAIGDLIAGPEPTFSFEFFPPKTAEGERLLWRAIRELEPLRPDFVSIT
YGAGGTTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRNVIGRLAGAGVRNVLAVRG
DPPGDPMGEWVRHPEGVLYAEDLVRLVKESGDFNVGVAAFPYKHPRSDDVDTDTAHFVRK
CRAGADFAITQMFFEADDYLRLRDRVTAAGCAVPIVPGVMPVTRMATIERSSQLSGAPFP
PALLARFERVAHDEAAVRALGVEVCAEMCARLLAEGVPGIHFITLNRSTATREVWQLLAP
TVAAV
>A0A286HJU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ag109_G2-15|TrEMBL
MNPTATARPAVGTSLLDDFSLEMTGKDVPKLEEAHAGIPRGTRINVTFLAGEDPGMRLAA
ARAVKRLGFVPVPHISARRLPSQRHLEEFLAGLDADGTAENVFVVGGDPARPEGPYEDAL
AVIRTGLLQRHGVRHVGISGYPEGHPAITEHSLWSALGDKSAVLGAQRIAGDVITQFGFD
ADRVLGWVEDVRARGVGLPVRIGVPGPAGVRRLMTYATRFGVGTSASIARKYGFSLTNLM
GTAGPDRFLHALADGYDPARHGEVKVHFYTFGGLRTTAEWIARFRRGDQEG
>A0A2D6KIS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTFELIPLKNLEDQIPFIPTGSTVSMTCSPVRTVEDTLDPCERLGNYGFSTIPHIAARMV
EGEAHVDQIVARITGLGIRRVFVIGGDAEPHGPFTDAASFLRSFLARKPDIDVVGIGSYP
DGHGTIPDDALISALLEKQEIITEAGLEGYMSTQMCLDHQKIGSWLAERRSAGVTLPCHL
GVPGAVDRTRLLTISLRLGIGHSARYLKKNRTSVIRLLSPGGYNPNKLITPLSKRAAELG
ITGIHCFTFNAVDTTEDWRQKTLADLRR
>A0A2G2J1U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robiginitomaculum sp|TrEMBL
MAKHSDISDPTVATPANLRVSFEFFPPKTEKMQINLWESIQKLETLNPDFVSVTYGAGGS
TRERTHETVAKIAKETGLSAAAHLTCVGSERGEIDEIAQAYWDAGVRHIVALRGDPEGGI
GTAYTPTQNGYGYSDDLVAGLQKIAPFDISVSAYPELHPESKNWDTEIDNLKRKVDAGAS
RAITQFFFSADTFFRFQDRVLDAGITIPIIPGLMLQPNYKGLKRMSDMCKISIPDAYHEL
FSDLDDDPKTRQLLTANAASELARNLRTGGVRHFHFYTLNKADLAFMVCKILGLQAQQK
>A0A368TC03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinitenerispora sediminis|TrEMBL
MLGSPTRSGAAPGLTARPRRISDLLTAGKPTFSFEFFPPKTPEGQRKLWRVIREIEALQP
SFVSVTYGAGGGTRDRTVEITERMATDTTLLPVAHMTAVDHSVRELRHLIGRFAGVGVGN
MLALRGDPPGDPLGEWVRHPEGLEYADQLVRLIKESGDFCVGVAAFPYKHPRSADIDSDV
EFFVRKIRAGADYAITQMFFEADEYLRLRDRVAARGCDVPIIPEIMPVVKLATIERSEQL
SGAPFPRRLAAEFERVADDPEAVRELGIEQATRLCERLLDEGAPGIHFITFNQSTATREI
YQRIAGSRQPAAAAARP
>A0A355DGU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MPTTNHPNGRRRPSVLARGDKAVHRRLLEGMTYELIPLRNIHDQSKFLPPGATISVTCSP
AKTIDDTLDLCEQFGDDGFTTIPHFAARMVEGEDHVDRIAARVAGLGIRRVFVIGGDADP
RGPFTDAAGFLRSFLDRGPDIDTVGIGSYPDGHSTIPEQALVDALLEKQEMIAAAGLEGY
MSTQMCFDAGTIGEWLALRRSAGVTLPCHLGVPGAVDRTKLLTISIRLGIGHSARYLKKN
RTSVIRLLSPGGFNPNKLIAPLSRRADDLDIAGIHCFTFNAVDTTEDWRQKSLRDLKR
>L8WIJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thanatephorus cucumeris (strain AG1-IA)|TrEMBL
MKLSEKLANHTSDAPYFTFEFFPPRTEQGYSNLLTRITGLASLKPIAASVTWGAGGSTRD
RSLDLAAFCQAENGLDTILHLTCTNMEKGTIDEALTTAMEKGVSTVLALRGDPPRGEEYW
IPTDPRFQHAEDLVTYIKQHPKFGNHFCIGVAGYPDGHSEGGSEEEQLTHLKRKVEAGAE
FIITQLFYDVEKFKSWLRKVRNTGELNCISGSRQPLLNPLVRYHRTSNTWNDAPTNVRNF
YPDDRFMQSYGTSTYPSQSRRHQEYGASLAVSMIRSILVDGDVKGVHFCTLNLEKSVRKI
LDELGWTHGTHHPNQIITDASQSPHILPAPADAPHPVTFTISPSEATQHAATSLAEHTRT
GTLRTAAEAINSGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPVRFPHVAISQWGRPTT
EQDLADLFLAYLNHKAPTTPFSPTPLSDESITILPHLISLTSKGLWTVASQPAVDGILSS
DPVVGWGPKDGRVFQKSFVEFFATEEELVKIAKAIEDSGDGWVTFFAGNNDVSAFKVPVV
SNAVTWGVFPGQEIAQPTIIDRDSFLAWKASIYTWTMREIAIEYVEQDDAFMIWHDFGLC
YSPDSPTRKLLENVTKTRWLVSIVHHDYKDPNALWDFLAKHLN
>A0A2E7QAS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MFENNRPDKXXQQQLLEGMTYELIPLKNVXDQAKFLPQNSTMSVTCSPAKTIDDTLXLCE
SFSADGHITIPHFAARMVESEEHVDSIIDRVHKLGIRKIFVIGGDADQRGPFYDAPSFLQ
ALVARKPDIDTIGIGSYPDGHADIPNSSLDXALFEKQEIILGAGYEGYIATQMCFDAKKI
AEWLXEIRXAGISLPXHLGVPGAVDTKRLLTISLRLGIGHSTRFLKKNRATALRLLSPGK
YDPNKLLSPLSRNALDLGITGVHCFTFNSVDTTEEWRQKVIKXLSS
>A0A2D7MT47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVIEHIAQADQCLFSFEILPPLKGQDINAIYHTVENLLEFNPPFIDVTYHREEYQYVEK
AGGLLEKRVVRKRPGTLGICAALQSKYDIDMVPHVLCGGFTKEDTENFLIDLDFLGINNV
VALRGDAVPTEVYFKPEKQGHSYASELVAQINGLNKGHYLDEELQHSHTTDFCIGVGGYP
EKHMEAPSLEKDIAFLKQKVEAGADYIITQMFFDNQKYFEFVKRCREEEINCPIIPGLKP
ISTIKQLSLLPHRFHVDLPQDLIQAVESCSSNAQVKEVGIEWCIAQSQELIEAGVPXLHY
YTMSRSENIHKIAKAIF
>A0A0P1KP76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea quebecensis|TrEMBL
MRVSEKLQKNREANGNSKATFSFEFFVPKTSQGVQNLYDRMDRMYQTHPQFIDITWNAGG
RLSQLSTELVSTSQSVLGLETCMHLTCTNMPRQLIDDALQKAYESGCQNILALRGDAPIT
SSEWKPCEGGFTYAKDLVRYIREKYGDHFDIGVAGYPEGHPEEEASPKLIQYLKEKVDAG
ADFIITQMFYDAENFIEWCRQVRAAGIEVPIIPGIMPITTYAAFLRRSSWCQINVPEAFM
AQLDPVKDDDQAVREVGTELVAQMCQKLLDSGYVTHLHMYTMNLEKACIMVLDRLGLLTE
DEEIFRDEVMPMPWRKSLHPQRRNESVRPIFWQKRPYSYVARTSQWTADEFPNGRFGDSS
SPAFGDLDLLGSTSIRQSPQRALELWSTPTKFSDIADLVIDYLHGKLKCLPWCDVALNHE
VDTTMPQLLDLNKHMILTLNSQPRVNGASSADKIVGWGPNNGYVYQKQYLEFLLPKSKLS
QLRDFVNDMPSLTYFAVDSADELHSNHPDDTAANAVTWGIFPGREVLQPTIVEKVSFLAW
KEEFFDILDEWKRIMGENNHSESVALLDSIIGDYLLVNIVDNDYVSDGDRIYDMLQRLY
>A0A1W1BYL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MFKRLANKLKNDTYITLETTPPHEPRFAPVIERIEELGLHTLVDGFTTTDSPLAKMKYNS
LFAAQMLQRRFNKPAIATMSMRDRNKIALQSDLLGANEANIRAILALTGDPASISDQPNT
KAVVEGDSTLLLDIIECFNSGIDYAGKPFKSAPDPILAFAVINSYAKNPKTLQKKMQKKI
KHGAKGIITQPVYDIENAQLLLELLDNANKECCNERKKAELVLGIFPITRLRTAQFLASH
VPGINVPPCWIEELRSASRDGVEKEYEVGFALSKKLFEDLKKLHPKMHIMTANNFALAKE
LLS
>A0A1W7QTT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrifermentans pelophilum|TrEMBL
MAFGSPIEASEIEVKIVEKMNQAQQFVSLEFFPPKDKNEWPAFFKTVDRLSQINPLFASV
TYGAGGSTKGDTLEIVKRLQSGNGLDTMAHLTCVGAYRGDLQRFLDDLALAGVKNVLALR
GDLPSDEPPEFSACRTLLYASDLAAFIRESHPEMGVGVAGYPETHPEATDPECDLGYLKL
KLDQGGDFVITQLFFDNRLYFDFVAKARAAGIDKPIIPGIIPVVSLKVIQRIISMCGATL
PPAYLAQLEEADRSGGAAAVQKVGIAYARRQAQELLGAGVPGVHIYTLNRDQAVLELVDG
LLPS
>A0A254QDA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium Cent15-Ar3|TrEMBL
MTLLEALATRVLLGDGANGTLLAERGFKKQPYDLANLEAADLVLAVHREYIEAGADFIET
NTFCSNRFKLEGRGVSIFELNKRGAEIAREAAGEKFVMGAVGPCGKPLAPFGHIEQDVAT
AAFTEIANGLVAGGVDGFFLESFVDLGEIEIAVAAIRAVSDLPVFVSKAFIEDGEMLAEG
LPSRCAREMSASGAVAVGANCIVGPQRMLDLVRMMAEESELPIIAFPTPGLPQLVKGEIT
YDTSPEYFAKATARLVEEGARVIGGCCGTTPAHIRAMREMIDRGIKVKPRTVVTRTEKEK
EELIQTPPSTLSEKISEGKFVVAIEMDVPRGLRIQKLIAGAKKLKEAGCDVINISDGARA
RLRMNPTAVSTLIQNEAGIEATMHFSCRDRNLLAVQSDLLGAHALGIRNILAVTGDPANI
GDYPSATSVFDIDAIGLCRIMSRFNDGVDLAGYSVGMKTAFTICAAYNPCAIDQALEDDR
LARKVAAGATLIYTQPVFDLADAQRSVEACKKLGVAVLVGILPLRSARHAEFMHNEVPGI
SIPEALRAKIAGAASDEIALEIGIEDARQLCRDIKGANGIYLMPPFGNADIAARVMEAVR
>A0A6G0RAC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora fragariae|TrEMBL
MDPPQTLDTCDSRLLPNDSLATSVSAFIKWEEAAALEAFPLAVVPSNHPHTREKGSKMPR
VSSIHVTKQKERHEEADELAATKFVLDDSTVWTGLSTEDTRAAGESEGDQERLLQRLHLV
QGLLTFVRMLRRSRGLQAEEEDDEAKTSAQWTPEWASLKRALGLQRLKAKQDAGADFIIT
QFFFDVDMIHWIADCKDAGITILPGYLSIQNYSSFCKFTSWCKTRVPESVLAALDTIKND
DAAVRRYGTQLAAETCQRLLAAGVNSLHFYTMNLPRP
>A0A7H9DSU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Empedobacter falsenii|TrEMBL
MKVTEHIERANGKPLFSVEILPPLKGQDVNATFKTLDPLVELNPAFIDVTYHRQEYIYKQ
KENGLLKRYQVRKRPGTVAICAAIQNHYKIDAIPHLICGGFTKEDTEDALIDLNFLGIDN
LLVLRGDPIKSEKSFVPEVGGHAHASELIEQITALNTGNYLDDELQESHAMDFCIGVAGY
PEKHFESPNLAMDLYYLKKKVELGADYIVTQMFFDNQKYFDFVKKCREMDINIPIIPGIK
PLTTFNQLTSIPQNFYLDLPEALAMEVLKSKDKERIKEIGIEWCIQQCKELIDFGVPGLH
FYTMSNSINTKKIAEAVY
>A0A8H7L087|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Athelia sp. TMB|TrEMBL
MKLSEKIKAHEPTKPFYTFEFFPPRTDQGFENLVSRIQRLSLLNPIAISITWGAGGSTRE
RSLELAGLTQAEYGIDTVMHLTCTNMVKGLVDNALRGAKERGIETILALRGDPPRGEEEW
APADPAFTHAVDLVKYIRSSPEFSSHFCIGVAAYPDGHPDHETDEEGEFKYLKEKVDAGA
DIIFTQLFYDVDGFLAWVKKVRAKGITVPIIPGIMPIQTYSSFQRLIKLCGCKVPPEVTA
ALDPIRNDDQKVKDYGVTLAVDIIRRITAEGDIRGVNFCTLNLERSVQLVLENLHWAGGG
PHDTTNPTSPITQPNSDLLTTPNVATLSAKTGLANLPATETEAGRGELNNAASWDDFPNG
RFGDYKSPAFGNQGLWGGTGITRSDAIAQWGHPKTLNDLTSLFLRQLHSETATTPFSSEP
LSPESLTILPHLEKLTHKGWWTVGSQPAVDGARSSDDIFGWGPRGGYVFQKAFVEFFAEE
ADVERIEKKVRESGKGWVDYFAGNIQGEVRTNVPEDGRNAVTWGVFTGQEIAQSTIIERE
SFLSWKDEAFSIWTEWASFYRPGSQERDLLDGVAQKRWLISIIHHDFKEPEGLWTFLFG
>A0A3B1DEX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MIISRKRDFQELLENIKNYKSFFLIGCSECASLCGTGSEKEVKELAETLKAEGKEVTGGI
VAKTGCQVLGTKKELKVYKDEVNNADCILVMSCGAGTQTAVELFEDKPVYATNDSLFLGN
MTRFQVFDERCSMCGKCILDKTGGICPITTCPKGLLNGPCGGMKDGHCEVSPEIPCAWVR
IYERMKKLDKLEELTGSVLDARDWSTGQSPRAFSAREKKGK
>A0A3B1BLB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MESQKKYPAQFSFEFFPPKTDKGVEKLKLVRDKLGALKPKYFSVTYGAGGSTQQGTFDTV
MSIRGAGFDAAPHLTCVGASRESLRNLLQQYIDNDIHRIVALRGDMPSGMHTSGEFHYAN
ELVAFIRAETGDHFHIEVAAYPEFHPQASNAQTDIDNFKRKIDAGANSAITQYFFNPDAY
FRFIDDCERRDIDVPIVPGIMPITNYSNLARFSDMCGAEIPRWIRKRLEAFADDTDSIKA
FGEDVVTDLGHQLLEAGAPGLHFYSMNQADASLAIWKNLGL
>A0A1W9XI54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_88|TrEMBL
MRVTDLYGSKKPVISMEFFPPRNEKAAEAFGSIIDDLAELKPDYMSITFGAGGSTRDGSY
QTVKQLMLDKNLPTVAYIAGYGLGPDELTDVLDKYKELGVETIFVIRGDKPGGDDFTPHP
DSFSYASDLIAFIKERYDFTLGCAGYPEGHIDSESLEKDIEYLKLKVDNGAEYVVAQYFY
DNLYFSEYVEKCRAVGIHVPIIPGIMPIYTVKLTKILSEVCGSTITDTLQSKLEAVDAGD
KDAVLNLGIDFATEQCRGLLKEGVSGLHFYTMDRSKSTSEIINRLKQENLL
>A0A4R2IV14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2541|TrEMBL
MFELVCEVEPPTRPELKKVRHQIGVMSPIADAFLIPDNHIGRATVSSVAVANEVQAMGSR
GIACLNSRDRNLLGFKRDLLTAAAYGVEQFLFVHGDDPAEGARTSQLTVRTMIEQARATS
YPGCNPFQVGAATRLRPVPRWKAEADFLYVQVSYDLDELLRWRDSVTLDIPVYAGVMVLA
SSKMAHNLAALPQLNIPSALIEAVDQDRDAGVDHACDLILRIRDSGAFDGVHLIPVSRYR
QVAARLEREL
>A0A3B0WIA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MSLANNTGSTVKISCEFFPPRTEAGVEKLQSVQEILDEAISPEYYSVTFGAGGSTRDSTL
EIIKLLSAKNINVAPHISCIGSTKQQLNDLLTEYKNLGVTRLVTLRGDIPKSGESTKELA
HANELVSFIRETTGNHFTLEVAAYPEYHPESTTPQSDFEHFKNKVAAGADGAITQYFYNI
DAYQRFIDNCQRENISIPITPGIMPITNFQSLTRFSDTCGAEIPRWIRKQLEAYADDKES
LQSFGVDVVSHLCNQLIERGVPGLHFYTLNQTTTTHAIWKNLSL
>A0A2I0L2R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Punica granatum|TrEMBL
MKVIDKIREAAVCADGEGAGSGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPNFCDIT
WGAGGSTADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALTTIKSNGIQNVLALRG
DPPHGQDKFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDVIGPDGMATLEAY
QNDLAYLKRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGISCPIVPGIMPINNYKGFLR
MTGFCKTKIPPEIMAALEPIKDNEEAVRNYGIHLGTEMCKKILANGIRTLHLYTLNMEKS
ALAILMNLGLIEETKVSRSLPWRRPTNVFRVKEDVRPIFWANRPKSYITRTMGWEHYPRG
RWSDSQSPSYGALTDYQFMRPRARDKKLKEEWTVPLSGIEDVCEQFKKLCLGKLRSSPWS
ELDGLQPETRIINEHLGKINLKGFLTINSQPAVNAERSDSPSVGK
>A0A3B0S7J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MTTLSQNAFNVARDPGGFTISFEAFPPMSEAGQGKLLDVAKNLEDFDPAFFSVTYGAGGG
TQERTLNTLADISQKTGHNLAGHLTCVGATKEQTNAVAEQYRKMGVKHIVALRGDTPDGV
DQYQPHPGGYKNAADLVAGLKEIGGFDISVGAYPESHPDSPSRNADLDNLKAKFDAGADR
AITQFFFDNHVFYDFMDSVQDHGITGPIVPGILLIHDFWKVKRFAKMCQTDVPDWLEARF
AGLQGDTAAQQLVAVSVAVEQVLEMAASGVRHFHFYTMNKSDLAVAVCRSLGLKPARNMR
SVA
>A0A428EAA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISSLQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3B0SK30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MHTPTISFEFFPPKSLDGSFQLWQAAQTLAPLEPKFVSVTYGAGGTTRKLTREAVGALHK
STGMNVAAHLTCVEASREETLAVADEFAAAGVSEIVALRGDPPKGTDSFTPHAEGFKDSC
ELITALAETGKFSIRVGAYPETHPEARDAAADIDWLKRKIDAGACEAITQFFFEADTFFR
FRDACDKAGITAPIIPGILPIENWQGTRKFAARCGAGIPGWLDDAFDKASRDGEGRHDLL
ATAVATELCTDLIEGGAEHLHFYTLNKPDLTRDICHALGVTSRAELRNVA
>A0A2S6I323|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lewinella xylanilytica|TrEMBL
MRVTEHFKQADGQTLISFEVLPPLKGGSMQAIFDTLDPLMEFKPPFIDVTYHREEYVYKK
RASGYYEKTAIRKRPGTVGICAAIMHRYGVDAVPHLLCGGFTKQDTENALIDLAFLDVQN
VLALRGDARKFEGRFIPEEDGHNYACELVGQIVDMNDGKYLDDLIKGEHASKTDFCIGVA
GYPEKHFEAANLEHDLRYVKQKVEAGADYIVTQMFFDNQKYFDYVDACRKVGINVPIVPG
LKPLTKLYQLNSIPRLFHIDLPDDLVREISQAKSSDARTQVGIEWCAAQSKELKERDVPC
LHYYTMGDSSTIQSIAEQVA
>A0A4T0M900|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia mellicola|TrEMBL
MIVDSQFSDIMYIPDGFVNLKSRLQRLSLLKPGFVSVTWGAGGSTDERSLELAAVARDLG
LDVLLHLTCTNMEKSRLSWALDKAKELGIDNILALRGDPPRGHEYWVESDKNLSHSSDLV
KFIRDNYADNFCIGVGAYPESHKDSSDAAQDLKYLKLKQDLGADFVITQLFYDSDAYLNW
LDKCLDIGIKIPIIPGIMPIQNVPSLRRLANLCGAHIPSVISDHLEPIKNDDALVKDYGV
ELSTSMVRQLIDKTNGQKEKYGNLAISAAHFCTLNLEKSVRRILANLDWSSGLDASSLEP
NGLTHNTTTGAVEPARLGNRLVAENCISHGHTADGPPPLSITAHEAAVRALHALKHHPPS
EDSGLPSSNKTSSGGNSLWDEFPNGRYGDIRSPAYGELDGWGASLKLSSQNALKQWGYPV
EVSDINEIFKKYINGQVASLPWFEENLDPESNSIKDYLFRLAEKGWWTVGSQPAVDAVES
SDQIFGFGPKNGWIFQKAFVEFWVPEHELEGLCKRLDGWKDGGYYAGNAKGEMKTNFYED
TINAVTWGIFPGQEVVQTTIIEDVSFNAWREEAFEIWLEWSMLYSPKSASQQLMKNVHDN
YWLVSVVHHDYKDTNGLWEFLLS
>A0A839PSF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terracoccus luteus|TrEMBL
MAHGTASSMVRAERFTRSIPEMVQADASTFSFEFFPPKDDAAATTLWEAIRRLEKLSPSF
VSITYGAGGTTRDRTVRLTQRVLESTSLTPLAHLTCVGHSRDELRRVVGQYAAAGVHNIL
ALRGDPQGGLGEPWTPHPEGFDHADELVAFIRSLGDFTVGVAAFPDGHPESRGVADDAEA
LVRKERAGAGFAVTQMVFDVENYLRLRDEVARRGSSLPVIPAIMPITNARQVVRMAELAG
QPMPTAVTDRLGRAGDDPAAVRAEGLAIATESSRRLLDEGAPGIHFITMNRSSATLEVFG
NL
>B0SQU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris)|TrEMBL
MHISEILGKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRHLTH
DLVVKLQNETGLTIVSHLTCVGSTKEEIGDILKRYDKSGIHNIMALRGDPPKGQQDFQQT
ENGFAYAGELVGFIKKEFPKMGIGVAGFPEGHPSTPNRLKEIEYLKWKVDQGADYICTQM
FFDNNQFYDFVERCEIAGIKVPIIAGIMPVTSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDVYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRKIYESLGVRNFDRIV
>A0A7X6DJ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramlibacter lithotrophicus|TrEMBL
MKTPVSFEFFPPKTPEGAAKLRTARQALYALQPEFCSVTYGAGGSTHEGTFATVKEILAE
GREAASHFSCIGATRDKVREQLAELRAMGIRRLVALRGDLPSGYGTGGEFQHASDLVAFI
RVETGDDFHIEVACYPEMHPQARSPEHDLRAFAAKVRAGANGAITQYFYNADSYFRFVEE
VRKAGLDIPVVPGVMPIVSSTQLMRFSDACGAEIPRWIRLRLQSYGDDSASIRAFGLDVV
TRLCEQLVAGGAPGLHFYTMNQAAASVEICKRLGV
>A0A378ATF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae subsp. pneumoniae|TrEMBL
MSFFHANQREALNQSLVEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKCSK
GWITTPKPVNWWGRISPWTW
>A0A380A748|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella algae|TrEMBL
MAFHHAQHAHSLNQSLSELNGDINVSFEFFPPSTPEMETLLWNSIQRLEPLNPKFVSVTY
GANSGVRDRTHSVIERIQQETELVAAPHLTLVDASDEELLELARHYWNSGIRNIVALRGD
LPEGSPKPTRFASDLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIEAGAGRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVGNFNQLKRFAAMTNVSLPGWLHRQFE
GLDNDPGTRALVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A0A2KTD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium expansum|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKALGLRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRQTHGDYFCVGVAAYPEGHPADTFQDVQDPARDIPY
LVEKTQAGADFIMTQLTYDIEAYQKFENTLRNHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIARRMDELKHDDDAVKRAGVDIVSEIVGGMRDIPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPSYSDAGDLAIEDDPASIPLDFPGRALRRRRASSINSQPHNRVIVDKL
SVHESSQDSVHEARADSAGIPAPPPNRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTANSARRLWGHPVDAKDMSTIFRRHVSGELHMVPWSEGGAEENGEG
LNAETELIRPELLKLIDGRGWWTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFC
SNNDYTNILKPMFAKHGHDKLTWFATNIKGDFESSLPVQPADVELDDLGSNPESVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTETYLDTTKNDSWLVCVV
GQQFGAGTKQGSKEEEDEVKWMWRVLAGEEA
>A0A258IQ43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 32-66-11|TrEMBL
MAGPIRASREIGKAPVGVSFEFFPPKSEEMERTLWASVARLAPLAPRFVSVTYGAGGSTR
ERTHATVERLVRETDLAPAAHLTCVAATRAEIDDVVRAYAKAGVKHIVALRGDPSSGVGT
TYEPHPDGYAHACDLVAGIRKLGDFEVSVSAYPEKHPESPSIDADIDYLKEKVDNGATRA
ITQFFFDNDVYFRYLDKVRARGIDIPILPGILPVTNFKQAANFAARTGASVPDWLAKRFE
GLDNDPETRKLIAAAVAAEQATDLVDRGADDIHFYTLNRADLVYAICHLLGLRAKGVEST
MPQAVAV
>F4V8T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli TA280|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMMKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0Q9H6T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. Root381|TrEMBL
MMNAFRPSRHGSCRPKVSFEFFPPKTEEMEVALWESVRRLEPLGPSFVSVTYGAGGSTRE
RTHATVKRMVEETGLKPAAHLTCVSASCAEVDEVIRAYWEAGVRHVVALRGDPAGGLGTA
YEPHPQGYHQTSDLVAGLKRIGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAI
TQFFFDNDVYFRYLDRVRAKGINIPILPGIVPVQNFRQTANFARKTGASVPQWLADRFEG
LEDDAATRRLVAAAVCAEQALDLIDRGATDLHFYTMNKADLVYAICHLVGVKPEAAAAQA
AAAE
>A0A1E4NGP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus sp. SCN 65-179|TrEMBL
MSGRTFSFEFFPPKTAEGAEKLRATRAQLAQLKPKFFSVTFGAGGSTRDRTLEAVRDIQA
SGSEAAPHLSCIGSTRESIREILGEYKSQGIRHLVALRGDLPSGTMDAGEFNYANELVSF
IRAETGDWFEIEVAAYPEIHPQARAWKDDLANFKRKVDAGADSAITQYFFNGDAYFRFVE
EVRALGVAIPVVPGIMPINNYLQLARFSDACGAEIPRWLRKKLESYGDDLVSIRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPSTTIWQRLGLS
>A0A140NIS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia stuartii (strain MRSN 2154)|TrEMBL
METALSFEISAMSKIDNTLEHLLKNTEELTPLFYTVNTEIGKTEWRDTYNTCCELKNLTH
VNVVPHIAINNKDECELCFIIEEYLKNDITELFVIRGDRHRFDEELPFNYGIELIDFIRR
RYPEVMIKSSIYPDYHKESIIPEIEIDWLRKKLQLGVTELISQLCLNKNAFSYMKKQLGN
DIPITISMMPMLNFSFIESFFKNNAIDYPLWIKKHIRPSNINNHRAFGIQLTQFLIGEYI
KENKRLHFFTLNNAQMVKKLFDKLR
>A0A1S2TF74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella algae|TrEMBL
MAFHHAQHAHSLNQSLSELNGDINVSFEFFPPSTPEMETLLWNSIQRLEPLNPKFVSVTY
GANSGVRDRTHSVIERIQQETELVAAPHLTLVDASDEELLQLARHYWNSGIRNIVALRGD
LPEGSPKPTRFASDLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIEAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVGNFNQLKRFAAMTNVSLPGWLHRQFE
GLDNDPGTRALVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>D7LWJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabidopsis lyrata subsp. lyrata|TrEMBL
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGSTA
DLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITTLHLYTLNVDKSAIGILMNL
GLIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPHGRWGDTRSA
SYSTLSDYQFTRPKARDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPE
TKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TLVEKSKAFPLITYMAVNKAENWVSNTDESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK
DEAFEIWSRSWAKLYPEDDPSRKLLEEVKNGYYLVSLVDNDYINGDIFAVFA
>A0A1E3YTF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. SCN 65-108|TrEMBL
MIAANAQGTGFPVSFEFFPPKTPEGADKLRAARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREQLAMLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPEADLNAYIAKVQAGADSAITQYFYNSD
AYFRFVEDTQRLGANVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A845A5H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantiacibacter arachoides|TrEMBL
MSYEAIHPNWEKPAGNMVDGYSLEMTAKEIEGLREAAPLIRPDTQIAVTFLPGEEIEQRI
EASCEVRRLGFEPIAHVSARRIKSHEELEHYLKETAERAQAKRVFVIAGDPPEPEGPFED
SLQIIETGLLEKYGYEVIGVGGHPEGHPNVDKDALWTWMERKLDAVRAHGMTPLIVTQFA
FDDDAIVEWLGEMRRRGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGISITN
LIGNAGPDKLVDGLDKKLGQEHGRVRLHFYPFGALTASAQWINDYDARHS
>A0A1V4TCR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccales archaeon PtaB.Bin134|TrEMBL
MTISGLQGSLDAGRFVVTAEIGPPRSCEVERLREMARMLRGWAHAFNLTDNQAANVRMSS
IASSLICLQEGLEPVMQMTCRDRNRIAMQSDVIGASALGIRNVLCISGDHQTFGNHPQAK
NVYDIDSVQQLMVLRRLREGANWSGEALPEPPQLYLGAAANPFADPFEFRARRLARKAEA
GAQFVQTQCVLDLERFRSFMQMVVGMGLHEKVHVMAGVIPLRSHKAALFMKNKVAGMSVP
DEVVERLRRASDPKEEGIRLCVETIQELSGIKGVHGVHITAIAWEDIIPRLVSESGIRP
>A0A521BSM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium rhizoplanae|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFNPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEEQVSDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWSIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A2S7EY29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas populi|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRRLKQKH
GFEAAPHLSCVGGSRQEIRELLKRYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGEAFRIEVGAYPETHPQASDALSDLRYFKAKVDAGADAAITQYFHNADAYFHFRDT
VQRMGVEVPIIPGIMPISNFSQLQRFSEQCGAAIPRWISKKMQSYGDDADAVRAFGTEVV
ATLCERLIVGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1W2B868|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocicer vacuolatum DSM 3385|TrEMBL
MNLKDSLKKKKFVVTSEIQAPMGDDDPQELIKSLNRVKGRVDGVSLSEVELEGVVGDSIQ
TCDLLRKNRFNAIYQTTTRDKNRFQLQRDLTLAHEAGVENLLVFTEDYRISGDSLQESMF
FHVDSGKLSSVLDHMKQGQTIDGNALDKKVDFMLGSGVETPWGKNLPKRGMEEMEDMINV
GTGYFLTTPIFDLDQFEKFIKQVNTFGVPVIAEVMILRTGGMAKFLNRHFKSGLVPEWAV
QKLLKAPDKTRASIELFADTIKGLKDLCQGVHIITIGGEEKLGEYLDAAKLR
>A0A1A6HC37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neotoma lepida|TrEMBL
MPPAPTLSSRNPAMVNEGSSSGSESPKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCQQRQEEITGHLHRAKQLGLKNIMALRGGDHWEAEEGGFNCAADLVKHIR
SEFGDYFDICVAGYPKGHPEAENFEDDLKHLKEKVSAGADFIITQLFFEANTFFSFAYSS
LRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGXVPGLHFYTLN
REVATMEVLKQLGMWTEDPRRPLPWAVSAHPKRREEYVRPIFWASRPKSYIYRTQDWDEF
PNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPN
RHGHTVTCLPWNDDPLAAETSLMKEELLRVNRLGILTINSQPNINGKPSSDPIVGWGPSG
GYVFQKAYLEFFTSPETVEALLKVLKKYELRVNYHIVDVRGKNITNAPELQPNAVTWGIF
PGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSRMIIQYIHDNYFLVNLVDN
EFPLDSCLWQVVEDTFELLNRHTTEREAQAP
>A0A081BF62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidicaulis marinus|TrEMBL
MVRLGDKIRGREDLRVSFEFFPPKTEKMEETLWDSIKRLEPLQPNFVSVTYGAGGSTRER
THATVARIVKETSLKPAAHLTCVGASREEVDEVVQAYWDAGIRHIVALRGDMPELGTPYK
PHEKGYQSVPELIRGIKAIGDFEVSVSAYPERHPESPDGDADLRLLQDKIEAGATRAITQ
FTFDSSIYGTFMERVEKAGIKVPIVPGIMPTTNFKGISRMAEKCGATVPGWLADYYEGLD
DDLTTRKLIAAAVAVEQVHDLERMGFRDFHFYTLNQADLTYAICHILGLKPSTKPTPGLK
AAE
>A0A4Z1CCC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides eburneiflavus|TrEMBL
MRNKRTTATLVRLLENARYEVLPTASTEEKVLEHVPRDRTITVTASPSKGLEATLDLAER
LTGHGYPTVPHLAARMVSGRGELAEIAERLRGKGITSVFVPGGDAEAVGDYPDALALLED
LRDLGSPFAHVGITGYPESHPTIHDDLTVQSMWDKRRYATHIVSNLTFDPAVVRDWVRRL
RARGVAMPLLLGIPGPVERAKLLGMATRIGVGESTKFLAKNKGLFARLAAPGGFTGETFL
ERCAPALGEDGAIVEGLHVFTFNQIGETEAWRTDMLERLRDGT
>I4BUC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetomicrobium mobile (strain ATCC BAA-54 / DSM 13181 / JCM 12221 / NGA)|TrEMBL
MKIKELFEKKRFVFSFEIFPPKPTTPLERIYNTLDELKGLKPDFISVTYGAGGSTRDRTP
QIAIDVKNNYGIESLAHLTCIEATREETCDLINFLIGNGVHNILALRGDLPQGQSAPKGD
FRHAVDLVSFLREKYGQAISIGGAAYPEGHIECEDPIKDLRYLKQKVDAGVDFLITQLFF
DNELFYRFMERADIAGINVPISAGIMPVVNKNQIERIVTLCGASLPQKFVRILHRYADEP
RSLEEAGIAYATDQIVDLIAFGVRGIHLYTMNKAHVARRIVSNVSTLRETMHGPKGEEAL
YEGR
>A0A117MAM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinimicrobia bacterium 46_43|TrEMBL
MDKGHETSQKPRNFLACLRDHVLLFDGAMGTMIYERGVYVNQCYDALNIQKPDLILGIHR
DYADAGADALTTNTFGANRFLLKKYGYEERTVEINRKGAELARQIAGEELFVAGSMGPPP
DRMEPLGKLTVRELREAYHEQAEALIHGGADILILETFSDLGMICEIIREIKSAFPKVPL
IGQMTVDKEGRTSLGSTPEIFASEIVRAGADVVGVNCSLGPSTMLEVAERIFRISPIPVS
AMPNAGLPQRVDGRNIYFSSPEYFSEYTRRFVQVGVRIVGGCCGTTPDFIRSMRNALRSI
QPRKRIEITSLPPQHDEDVDLIPTSKKSRLAEKISRGEFVTTVEIVPPQGPDPRKAVEQS
RILFESGVDAINIPDGPRALSRMASSYLSLIIQQETGGEVIQHFTCRDRNLLGMVGDFLG
AYAAGIRNILIITGDPPKMGTFPDASAVFDVDSIGLTRVASILNHGRDLGGNVLKKATGF
FIGVGANPGAINPEEEIRRLEEKRDSGAEYIMTQPVFDPEIFLTFMDRIRHINLPVIAGI
WPLVSVRNAEFMNNEVPGANVPDWVMERLKRSRTRDEARETGLAIARETLRILKPYLQGA
QISMPFGNVKYPLEVLKEVLS
>A0A811GA02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bouvetii|TrEMBL
MTKRVPISFEFFPTKTDVGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKTRIAELLELYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFTIEVAAYPEMHPQADSFDKDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A0R2I5V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carnobacterium maltaromaticum DSM 20342|TrEMBL
MGLKEVLGTKLLIADGAMGTLLYQYGIDRSHEELNCSHPEAILKIHQDYLAAGADIIQTN
TYGANYIKLARYGLEDQVQKINRAGITLAKEARGDKEAFILGTIGGIYGAVDTKIHDPGM
EEISRSFKEQLYCLLLGGVDGILLETYYDLNELKTVLAIAREATDIPIIANVSIHEVGIL
ANGQSLATALEELADLGANVVGTNCLLGPHFMAQSFESVPLIPGKVLAAYPNASFPTMEN
GRIVYQKETDYFKLFGELFRKEGVGLIGGCCGTTPEHIAAYRKGLTTLDLVTQKKVKALT
TYRFQAKQETGKERLLDKVQREFTVLVELDPPRTFNTTAFFKGAARLKEVGVDAITLSDN
SLASARISNMALSAMLKYEYDIQPLVHLTTRDHNLIGLNSQIMGFHKLGIHDVLAVTGDP
AKVGDFPGASSVFDVSSFELIKLIKNFNQGIAYTGKNLREKTNFQVAAAFNPNIPRLERA
GCLLKKKQEAGADYFITQPIFDSEKVKILKEVMKTAGVTIPIFIGVIPLVSSRNAEFLHN
EVPGILLTDETRERMRMAEEEGRGLEVGMTIAKELIDEICQEFNGIYLMTPFMNYEISAE
LCEYIQAKKQQEKSICSCGQVHSQ
>A0A1F7PFJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium RIFCSPLOWO2_12_FULL_71_22|TrEMBL
MATRQDTPFREAMRSLLVFDGAMGSLLYERGVFVTQNFEQLNVTRQDIVRKIHDDYVGAG
AQVIETNTFGANRFRLDRHGLADQVRAFNVAGARLARQAAGETVWVGGSMGPSGLVPGVA
TQAELALVSATFAEQAAALVEGGVDVLVLETFRHLAEIRLALEAAHEAAPGVPVIASMAF
DPSGTVADGSTPEQVASTLRDLGADAVGVNCGDGPQLALAIAERLRGAGLPLCVQPNAGL
PRNVDGRLLYMATPEYFDVFLRRTAQLGATMIGGCCGTTPEHVRWMAKSARMLGDRRVEV
APVRAVTTAEAFAGLAPTPLAERSAFAAKVAAGRFVVSVEVNPAPGLDPSKALAGAKMLV
DSGVDIVNVADGPRAMARMSNLAFCTLLLERHGIQPILHVCGRDRNLLGQIAHLLGAHAV
GIRNLVIITGDPPKVGDYPEATAVYDLDSIGLLHVAANANRGIDPAGKPLPGGKTAFLLA
TGFEPGAADLDREILRLERKKAAGAELVMTQPVFQQDLLEKVLERIAHLELPVMVGVLPL
VSYKNAEFLHNEVPGMQIPEEIRERMRRTPGGEAARKEGVRIAREMLFAVRDRVQGAYLM
PPLGRYELALEVLEGLKA
>A0A385NAB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WCHA55|TrEMBL
MSLLAQYFAQQQFCVLVEYLSAQQAQWPVKTQFAGFPVAMTLADRVHADDDEAPLMVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDAKTQGQKNLLLLTGDKLKQHHYSHDVEPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMAAL
QDAHVFLAQHQYAQKILACVMPLTLTRAKFMLKHKVAGIVITPHMLQVLQQEKEQGLSDR
VYARCALQILMCRHLGFAGVHLSACHQPEEQMLLESYIEEYWHLSSAECERLWNTLWQVQ
TGTEFHPKLTYYSRPATSSQIIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDRTKANN
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTAILKEKLIPTVSIAVRGTSSWKNWYAESAD
>A0A416L2I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF27-2AA|TrEMBL
MKIRDILAKNEPTLSFEVFPPKTEDKYESVEMAASEIAKLNPAFMSVTYGAGGGTSQYTV
DIAASLKAKGVTPLAHLTCVSSTREKVHSVLEQLKAEGIENVLALRGDIPKDGKVENDYR
YASELIAEIKASGDFCIGAACYPEGHVESVNKTEDIQHLKEKVEAGCDFATTQMFFDNNI
LYNYLYRVREKGITVPVIAGIMPVTNVAQIKRICSMSGTYLPARFKAIVDRFGDNPAAMK
QAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIQNSLSEIIR
>A0A3R6WMA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM05-9BH|TrEMBL
MKITQLLQEDKVTLSLEVFPPKKDTAVEQVSQSVRAIAALHPDFMSVTYGAGGGTSAYTV
QLAQEIKAEYDVPSMAHLTCVSSTKETVKKQLECMQEAGIENVLALRGDIPADTEFPLPD
QFHYAVELVRYIKQIAPEMCIGGACYPEGHPEAVSKAQDIQHIKEKVDAGCEFLTTQMFF
DNSIFYNYMYRLREAGVLVPVIAGIMPITRKNQVERSIQLSGSCVPARFKSIVDWFGDDP
AKMKQAGIAYATDQIIDLIANGISHIHVYTMNDPEVAAGIMNNLSAILH
>A0A1C6N0U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WMMB 322|TrEMBL
MAIGISATRTDSSTTVRDLLATGQRSYSFEFFAPKTEKGERSLWNALRRIEAVSPTFVSV
TYGAGGSSREGTVRNTERIATETTLTPVAHLTAVNHSRSELRNVIGQYADAGIRNVLAIR
GDPPGDPMGEWVRHPEGLTYASELVELVKESGDFCVGVAAFPEMHPRSDDWDTDVRHFVN
KCRAGADYAITQMFFRVEDYLRLRDSVAAAGCETPIIPEIIPVTNVKQIETFAQLSNATI
PDELADRLRSVEDDPAAVRSVGIEYATEMCATLMAEDVPGLHFITLNNSTATLEIHQNLG
LHNRP
>N9LUZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 101934|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADNFDADIKRFCEKAHAGANAALTQFFFNPDAYSYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A5J4E9V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium MnTg04|TrEMBL
MNVTDLKNRLAEQSAQISSVNVSFEFFPPKTPKMESILWDSIENLAPLNPGFVSVTYGAD
GSTRDRTHRVVRRILTETDLVAVPHLTCIDASREEIQGIAKGYFDLGIRHIVALRGDLPA
GTTEYRPRKDGYAYASDLVTGLREVADFEISVAAYPEVHPEAPSQRFDLDNLKRKVDAGA
TRAITQFFFYNDAFLRFCDLCAANGIDVPIVPGILPITRFPRLVQFAKACGAAIPPQISQ
QFEGLENDPDTHQLVAASVAIDQVRRLQQHGVENFHFYTLNRSRLTYAICHILGIRPQQG
IAHASA
>A0A5P3XHD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraclostridium bifermentans|TrEMBL
MSLLREALESGNFAITAEMAPPKGIDLSHLVECAKAVKGRVHAVNVTDFQSAVMRTTSLT
TCKLLKDEGLEPVLQVTGRDRNRIAIQGELLSAGVFGIENMLALTGDHTIVGDHPQAKPV
FDLDCVGILQTAQKLSQGTDMVGNQLKGSPEFYLGASVTPRYTPIEIQLLKMKKKINAGA
KFFQTQAVYDIDTMREFKEHTKEMNTKILAGIIPLKSPGMAKFMNENVPGIYVPDELIDR
LRSVGKENWASEGIKIAGELIQQLRDEDLCDGVHIMAIGAEENVPAILDAAKL
>A0A544YJA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbispora sp. SCL1-1|TrEMBL
MALGLPSRLPDRVPTVRELLAAGERSFSFEFMPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPRGGNPLDEWVKHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSATIESDTKYFV
QKCRAGADYAITQMFFRAEDYLRLRDRVAAHGCDTPIIPGIMPVTQMSTIARSEQLSGAP
FPPEVAERFAAVADDPAAVRRLGIEHAIEMCQKLLDEGAPGIHFITFNRSSATREVFQAL
HSVPAAAVAG
>J4TMG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptostreptococcaceae bacterium AS15|TrEMBL
MKVKDILRKNVINISFEVFPQKYGQPMEPIKSTVDAISKLNPAFCSVTYGANGGASENTV
KVASYIKNELKTSVLAHLTCVSSSKDDIDGKLQELKKNNIENILALRGDIIDTEKFEQKK
DLLYASELIEYIKDNYDFCVGAACYPEIHPESRNKDTDLAFLKLKQEVGADFFTTQMFFD
NSIFYRFMYRLRSIGVKIPVIAGIMPVTNVIQLTRIKQLSNADIPAKFMSIADKFENDKE
SMKQAGIIYACNQIIDLISNDVNNIHIYTMNNASVAEEITKNLSHIIYQ
>A0A382AE66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MVTQTRIALIFSRLVVGLIHQPSQILLPTRFRRAAQVYSFRSSNPGLLSTNSFTLSDLLV
QRFIEALSGEAFVLTAELSLSPKLNSTAIVKMAKELSDFVSGVQIPDHTNARPHISNLTA
SGLLLQAGIDPIMHMNSRDRNRISLQSDLLSAQVVGITSILLMRGMDLPPDHRPRATSIF
DVGAIDFITTAAAIRDGGALSAARDDDVLPFQIGAIAQVFDPAPGWTPEKLKAKTDAGAN
FIQLPLCMNLEILRRYMQQLISAKLLWKAKVMVTVAPFTSRQEAEATKASLPDSMIPDSV
LQQLGDSSDPRRTGIEICINMLHAMRQIPGISGANLLVL
>A0A7V1ZKP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MRFPDFFKCAKRPIISFEIFPPKTEKALENLLQVIPELIELSPDYITVTYGAMGSTREKT
LEIASLIKQHYNMETACHLTCVGASQREIDNILIRIYKAGIQNIVALRGDPPRGERDFTA
PADGYSYAYQLVEHIRRFERTFIGQENFFGIAVAGYPEKHIEAPSLEEDILHLKRKVEAG
ADIVITQLFFNNEFYFNFVKKAKASNISVPIIPGLMPIVSVRQIKRITSMCGATIPPSLQ
EELEEAIDDDEKASEIGIRQCIKQARELLESGVPGLHFYVLNKSQHISRIMSAIKPYIYP
RS
>A0A382MFW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKIIEKLNGSSPIFSFEFFPPKDSDGFTTLFETIGRLKPSDPAYVSVTYGAGGSTRAKTV
DL
>A0A7V5M0L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium|TrEMBL
MKLSELFSKGKFVITSEIGPPKGTNIEPLLKEAEELKGKVDAINVTDLQSSVMRLGSLAV
CRLLKERGIEPVFQITCRDRNRLALQSDLLSAYVLGIENVLCLTGDHNVLGDDPQSKPVF
DLDSVNLLRAAKGLMEGKDMVGNKLDGSPDFCLGAVANPGADPLEPQVIKMELKVEAGAQ
FFQTQAVYDVKKFEQFIRATEHIKVPKMVGIVLLKSAGMARFMNANVSGVFVPEKLIKIM
ASASKEERPKKSVEIAASLIKELKGMCQGVHIMPLGWDKYVPDVLEKAGLI
>A0A382MS03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MMLANSDSVRLIRDIYADRQSVDRPVISIEFFTPKTSKGDQVLCESTLPALIRLRPDYCS
VTYGAGGSTKSKTLSVVDMIQRQFGLTAMAHLTCVESSKNDIGAILDEAKELNIRNILAL
RGDPPG
>A0A381PM64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
VSQPQISYEFFPPHTKAGITKLVETAQVLAATDPAYFSVTYGAGGSTRTRTYETVVKLME
NGMTMAPHLSWGSDSESTVVSLLDKYRELGVTRIVALRGDPPSGIGSIAPIRRAHSLVDL
IRRRFGDTFIIHVAAYPETHPDALSPEDDIRFLRKKIEAGASDCITQYFFNADSYFYFID
RCQAHGIETPIVPGIMPITNYEGLVRFSDGCGADIPRWIRTRLAHLVDKPEDLLAFGIEV
VTNLCERLLNGGAPGIHFYTLNKPVASAQIARNLGLG
>A0A1Y4LYV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus pullicaecorum|TrEMBL
MELREYLKHKTLLFDGAMGTYFRSVHPEYPGKCELANCNAPAKVAEVHKNYLESGARAIK
TNTFAANTHALECKFDEVRTVIRQGWKIATKVAEPYRAFVFADIGPITDPDGEYEQIVDE
FLALGAKNFLFETWSDDDDLYALAAYIKARCPDAFLIASFAVSPDGFTRQGLSARAVLER
VTNCPVIDAAGFNCVSGPNHLLAQARANADLFGKERPAADPAMLSVMPNAGYPTIVDGRT
FFENRAGYFASRMVEIVAAGAKIIGGCCGTTPEHIRLTAEALNEEEIKPEPAAAQVEVKP
RKVKNRLADKFVAKKRVIAVELDPPADDNLEKFMAGAKALKEAGVDAVTIADCPIARARA
DSSLLAAKLRRELDIDPIPHMTCRDRNINATKALLLGLSAEEVRNVLVVTGDPIPSAERD
EVKGVFSFNSAVLAGYIRELGEQGVTAPFRVFGALNVNAANFEVELRKAKRKVEQGVAGF
LTQPVFTSRAFENLIHAHEELDADILGGVIPIVSHRNALYMNNEVAGIEISQGVINRYEG
LDREAAEDLAVDLSVQLAQRMEPYTAGWYFITPFQRVSLITRILRELNKSTETDPS
>A0A6N0LN95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. TCL240-02|TrEMBL
MYHTHSHTAFRRAVQAGEFLVTAEVAPPKGGNPAHMIQMAATLKGRVHAVNVTDGSRAVL
RMSSLIASVILSQNGIEPICQVACRDRNRIGLQADLMGAHALGIRNILALTGDPVKAGDH
PDAKAVFDLEAVRLLQLIRKMNQGVDCNEKPLTDGALDLFVGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFERLEKFMDTIASGYKKPILAGIFLLKSAKNAQFINRCVPGVN
IPQHIIDRLAKAKDPFEEGVKIAAEQVQIARQLCQGVHLMAVKREDAIATILDLAGIAPV
NQLVSK
>A0A656D1Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kryptobacter tengchongensis|TrEMBL
MKKPFLERLLDDRPIICDGAMGTMLDLYEYPEQPRCIHNLLNPDIVARIHREYIEAGAEI
IETNTFDANRFRLEFYHLQDKIKEINRAGVEIAKSVAGDDVYVAGSIGPTGKLIEPLGKI
KIQQVKDVIKEQAEILISEGVDLIILETFVSLNELDAAIEAVKEISDKIPLIAQKTFPED
GAILATDFPIEVVKHIKGKGVTVVGSNCTVGPQRMFSIIKSMYQDDVILSAQPAAGIPTL
VDGRSVYHASPEYLATYAKQLVEAGVKIIGACCGSTPSHIRAIANAVKDLRLKKPKIEIK
VKEQGQVETQQERGSKAEVVVLEAESSNFAKKIGKKFLTTVELDIPRGLDISSVIEGAKY
LKENGIDAVNITDGARARFRMDPVAISHLVQTKTGIETITHITCRDRNLIGLQGLLLGAW
ALGVKNILAITGDPTKIGDFPQATTVGDVDSIGLIKILRNMNHGLDAVGNTIGEPTHFLI
ACAANPTAQNLDYEISRLEKKVEAGAQIVFTQPLYEIQTLELFIKKIEHLKIPVMLGVLP
LRSYKHAEFLHNEVPGINIPAWVREKLFLARDDAGKVGIEIASQFLKEAKPLVQGVYLLP
PFKKYHIAIEILQKI
>A0A7V9QZ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MRNKAATQAVVRKALATARYEVLPTAKVEQTLVDAVPRDVTLTVTASPAKGIEATLDLTS
RLVAHGYRVVPHLAARMISGNSELTEIADRLVGIGVTNVFCPAGDADPPAGEYAGSLAML
EHLTQLGRPFAEVGITGYPESHPAIEDDVTIQSMWDKRQHATYVVSNLCFDSEAIGGWLG
RMRRRGITLPVLLGLPGPVERAKLVSMAAKVGVGQSVRFLKSHATTFARIAVPGGFSPER
FLQKSAPLLTDPALQVRGLHLFTFNQVAETEAWRQEVLGRTDARSQG
>A0A381TDB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MTSTTSTRLDRLPATAGAAAPPVRLIRDIYAEQRMLGQPVLSIELFPPKTPKGNALLFEH
ALPALRDLEPDFYSVTYGAGGSTRDRTIAIVDRIQREHQTTTMAHLTCISTSRADIEHFL
LDARKRGIRNILALRGDPPLDDIGPVEPGFEYSYQLVEFIKELGGFSIGTAGFPESHIAC
TEGKHVDWQRLKAKIDRGADFVLTQLFFDNDDYFAFRDYLTETLGVSVPITPGILPILST
DQIKRFTSLCGATLPAAVSAKLDAYGNDAAAVGEFGVEFATRQCEALLAGGAPGLHFYSL
NKPHAPTRIIGNLGLRG
>A0A382VL30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
IPTFNLGAVVNPCSADLDTEVRRMQQKVEAGAKFFQTQAVFDLEKLERFMHMVRPMNVPV
IVGIMVLKSAAMARNVNASLPGIDIPDRLIEEMDNASDGDSVGVAIAGRLLNSVKAFCNG
VHLMTIGRERNIPRVIQAANNLKGD
>A0A7X3RTV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MNFSEYKNKKKDTPLISFEVFPPKDDPEFEKLKDTLARLAELSPAIITVTHGAMGKGRKR
TAEVASYVKNVIGMESACHLTCIGYSEKEIDLMLEQIEQEKIRNIVALRGDIPKENGEKL
LSEGAFQHANQLVEHIRKYEKEKTQRFSIAVAGYPEKHIESPSFEEDISNLKKKVDAGAD
IIITQLFFDNRYYFDYVDRVRAAGIDLPVIPGLMPVLSSKQVIRISSLCGTEIPEALRKK
LEDAGDDNRKAVEVGIAQCRDQVRELIAEKVPGIHFYVLNRTSHIEKILESV
>A0A1E5TVR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus equorum|TrEMBL
MSQLIDKLKNNILVADGAIGTILYSEGLDTCPEAYNLTHPEKVAHIHRSYIEAGADIIQT
NTYGANFEKLKDFGLEHKVKEIHQSAVKIAKEAAKDDTFILGTVGGFRGVKQEDLGLSAI
QYHTEIQVDTLVESGVDGLLFETYYDLEELTNIIKATKRKHDIPIIAQLTALNTNYLRDG
TEINIALQQVAASGADIVGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSQF
KYSDNAEYFGNVAQKLINEGVRVIGGCCGTTPEHIQFIKSSIANLKPVADKNVIPITKYT
STSSKKTQSQSLTSKVKQRPTIIVELDTPKHLDTDTFFRNIKKLDDAHIDAVTLADNSLA
TVRISNVAAASIIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLLDINEILTITGDPSKI
GNLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKTKTNFNIAGAFDPNVRKLDGAVKR
LEKKLESGTHYFITQPVYSTEKIKEVYEATKHLDVPFFIGVMPVTSYNNAIFLHNEVPGI
KLSEEVLEQFEAVKDDKTKTKELSLKLSKELIDTVHEYFNGLYLITPFQKVDYTLELAAY
SKSITSTKQEAIL
>A0A382DTN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MTFAKELWDGNFPITLEITPPKISKPTVLLRRASLLENVSSAVNIIHRPNRQSSLAAALE
LQKNHIEPIWHLTVGGKSRDTIQSEIENAQAAGLKNILCLLGDNTSKGDLKVHETITLLR
EKLSPPLIATAFDQYQDKSSKYDILSKKIAAGATCIWTQPVLESRKLQKEAERLKSTYSD
TLIIAMAMPLIRGDQLDRITERLKIPKQPNLENRINAGENEA
>A0A7K1KN11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio alkaliphilus|TrEMBL
MFIPEAIRAGGRPFVSVELLPPRSEAEQEGFWLAVEAVKAVRPLFAAVTCGAGGRGAVGT
AETAGILAREHGLTVMPHLTCVHEEPSGLPARLEALQGAGIRNVLAVRGDFPTGETARPG
GFAHASDLVARVRRLAPDIAVGVAAYPDGHPDSRSLVDDIAFLKFKLDQGADFAVTQLFF
DNRRYFDMVDRLAATGCHKPVIPSVLPVRGLGQIKRVAALCDAPVPGKILAAMEAAHAKN
GDQGVRRLGVSLAAAQVEELLRHGAPGVHLYPFNRADLCLEVVERAGLLP
>A0A1F0CJU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC069D09|TrEMBL
MSKFLEKLKTDILVADGAMGTLLYTYGLDTCHESYNVTHPEKVLAIHQAYIEAGADVIQT
NTYGAQRHRLKNYGLEDQVVSINQAAVNIAHQATLGKETFILGTVGGFRSQRQCDLTLDN
IVEETLEQVEALLATGQLDGLLFETYYDIEEITTVLKIVREMTDLPIITNISLHEAGVTS
NGKPIVEALSQLVMLGADVIGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASQLSLDGE
NSQYQFSQNSEYFGKSAELLVAEGVRLIGGCCGTTPDHIRAVKRSIRGLKPIERKVVTPI
IPVKDFVRRIRRTDTLVDKVKKEVTIIAELDPPKHLDIVQFQKAIRAIDQKGIAAITLAD
NSLSNTRICNLSIASLLKDEISTPFLLHIACRDHNLIGLQSRLLGMELLGFNHILAITGD
PTKLGDFPGATSVYDVTSFKLLSLIKQLNQGLSYSGASLRRPTDFTVAAAFNPNVKNLTR
TVKLIEKKVASGADYFMTQPIFDHSVLKELADLTKTVEQPFFIGIMPITSYNNAVFLHNE
VPGIKLSESFLSALEKVKDDKEACLTLALNESKSLIDEALNYFNGIYLITPFLRYDLTLE
LIDYIQKKQVRKSS
>A0A7K1KLS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio alkaliphilus|TrEMBL
MHVCDLIEKHSPFLSLEFFPPKEKDAWPGFFEVVEKLKELGPLFASVTYGAGGGTQDNTL
EIATRMKRDHGIEPIVHLTSVGASAEKLDAFLASLTAAGIENVLALRGDPPRGQEDFDFE
SQEFRHATDVIEFIRQRYPNICVGGAAYPEPHPESPSIQSDLDMVQLKVAKGAKFLVTQL
FFDNRLYFDYVARLRAMGANVPVVPGVLPIMSLRSAKFILGLCGAAIPGKFLSALEKANE
EGGDEAVYALGIDYAVRQAQQLIDGGAPGVHLYTLNRAEACLEIGKNLKI
>A0A381YTX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MERKLWSCVAQLAPLSPRFVSITYGAGGSTRQRTHATVERILAETSLTPAAHLTCVGTTR
DDADEVVQRYWDSGVRHLVALRGDSADPGRPFAPHPQGYQTAVQLVAGIRKIADFEISVG
AYPEIHPDAKSQEADLDNLKRKLDAGANRAITQYFFDVDDFFRFLDRAQNVGISAPIVPG
ILPVTNFATVVEFSKKCGTTIPVWMQDLFAGLDDAPEIRQLIAATVAIEQCRLLLEQGVS
EFHFYTLNRAELTRAICHALGLRDYREDSLCELNVPGR
>A0A381YM24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MSAGPTELEAKIDLLKGSVHAINITDNPGATAHISSLAGSVIVLNKGIDPILQMTCRDRN
RLAIQSELMGASALGIRNVLALSGDPIRVGNQPDAKAVFDINSKTLLSIIEDMNSKGQTM
AGRELLTKAEFFPGAAAIVHDPEIDWDPKKLSNKAKAGAKFIQTQFCFDVELLTRYMDRI
VASGLSEQLYFIVGIGPLRSDKSAKWMKDKLFGTVMPDNIVSRMAQAKDQVQEGIDICAE
LIDQFREIPGVHGVHLMAPRNLSAIAPTVARAGIKI
>A0A382HZ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
IMDVNATELIRIANIMKNDEKIASQGNFFLGGVVTAHAPKPQWPAKNITEKIDAGAQFVF
THTCLDLDLLRTYMQRLGETKLLWSCHVVAGIVLLSSVEDAQWVSKNRPNVIIPNDIIAR
LRDAKNPEQEGIEICAEQLQELSKIPSISGAHIIASEKLTNIPIAISKSGICKENIAN
>A0A3G2W8N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis pv. commiphoreae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGAAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCQRLIAGGAQALHFYTLNLAKPTTQVLQLLGR
>A0A3N5VIE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MHIRDILSGSKPSLSFEFFPPRGTAAWEDLYQTIRELEALRPSFVSVTYGAGGTTREMTH
DLVVRIKQTTTIPPVPHLTCVGHTKAEVLAILERYAAAGVANILALRGDPPRDQPDYDWS
QGDFRHAADLVRFIRSFNETGKHPDPRGFGIGVAGFPEGHPSTPNRMQELDFLKSKVDEG
ADYICTQLFFDNHDFLDFRDRCRLAGIEVPIIAGLMPVTSLPGMKRMAELAAGARYPAKL
IRALNRANSSPGVVERVGIHYAAEQCAGLLNEGVDGIHFYTLNKSHATREIFHSLGLDTS
A
>A0A523S6H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium|TrEMBL
MSFAEKLKSGKFLVTSEVGPPKGVNIDKSLEEAEILKGKADAFNVTDLQSSVMKLGSLVV
CHLLAERGLEPVFQLTCRDRNRLALQSDLLSAYVLGIRNVLVLTGDHPILGDHPGARPVF
DLDSVSLLEVASGLMEGKDMKGNELDGKVEFCLGAVVNPGADPLEPQLIKMEKKIEVGAK
FFQTQAVYDLKTFEKFMKKVEKFEVPILGGIVLLKSAGMARYINKNVAGVSV
>A0A143ZJG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. 9140|TrEMBL
MRGFPNASGDLLPGHSSRGRLEQVLRRGEFAVTAELNPPDSADPEEVYARAAVFEGWVDG
INAVDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQGDVLGAAAMGVANILC
LTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDHAKFLSGRKLTAPPRVFLGAAINPFA
PPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFRAYMEKVRDLGLHEHCHILVGVGPMASA
RTARWIRSNVPGVHIPDAIIARLEGAADQKKEGKQICIDIINEVKEIAGVSGIHVMAYRQ
EEYVAEIVHESGVLKGRRPWRREQDPADAGVAERLDAAREGDIQDQESLAETAAKRPH
>A0A2T0WWN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Donghicola tyrosinivorans|TrEMBL
MTAPRISFEFFPPQSLEASFRLWDTVQVLAPMGPRFISVTYGAGGTTRDLTHEAVTTLHK
TTGLPVAAHLTCVNATKDETLNIANSYAEAGINQIVALRGDPPKGSGGFQKHPEGFADSC
ELISALADTGKFTLRVGAYPEKHPEATDHKADVEWLKRKLDAGATEALTQFFFEAETFLR
FRDACADAGITAPIIPGILPIENWKGVKKFSAACGTSIPAWLDEAFDKAIRDNRQDLLAT
ALCTELCDELLREGVEDLHFYTLNRPELTRDVCHAIGVTPQVKLENVA
>A0A3C1GS84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLTTFDELNQLSPTYFSVTYGAGGSTRDRTLSIVQALLE
RSDTPVAPHISCIGDDKAEIAELLDLYKALGITRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSADHFHIEVAAYPEMHPQAKSFLFDIDNLVNKYKAGADTAITQFFYNADSYLHLR
DALEQRGIDTVAQP
>A0A662C8H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquificae bacterium|TrEMBL
MRVRDILKERDLAISFEFFPPKSHQEEEALFENLERLKKWNPAFVSITYGAGGSTHDKSL
EIAYTMKEQGLNVVAHLTCVGATKEDLARTLDWLAERGIENILALRGDPPQGEKTFRPVP
GGFRYAYQLVEFIKRGWDFCVGVAGYPEGHIENPDKEADLRYLKLKVDKGADFVVTQLFF
DNRFFFDFLKRAKAIGIKVPIIPGIMPITNLKQVMRFTQLCGATIPRALLEWLEEGSTPE
EVRRRGIEHAHLQCKELVERGIKALHFYTLNRSRATEEILTRLLGEPEV
>A0A8H4JA34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryosphaeria dothidea|TrEMBL
MEKITDKLAALPPDGRYFSLEFFPPKTQMGFANLQNRLERMASALHPLFVTVTWGAGGST
ASKSLELAELTQRQLGLTTCLHLTCTNMSRSLVDDALEQAKTLGVRNILALRGDPPRSEE
YREGEADKDNDSNKDFTWAVDLVRYIREKYGDYFCIGVAAYPEGHSDQSHPDKQDPKFDL
PYLIEKTKAGADFIMTQLFFDIKAYEDFETMLRNDPSGVFKFIPIIPGLMPIQSYQILRR
TTKLSHAKLPAQVLERLDAVKGDDEAVKSVGVDILSEIVEKVKKRPNPGPRGFHFYTLNL
EKAVAHIVERCHLIPPAAPDENEEEAVTIDDIPVNGDGPSDSLKVKDRRRASSANMTPHN
RVVVDRPSTSSNKSYEALADEAGVPKDKIMTRANTLAISEGEGSLGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHVSIPQAIRLWKYPTSVEDISDIFRRHILGDLEAIPWSDEGLN
AETETIREQLLKLIGKGWWSVASQPAVNGVKSTDSIFGWGPKNGYVFQKPFVEFFLSSAD
WKKLQAKLDELSDVTYFAGNNAGDFSSNDEQSVNPVTWGSFAGKEIVTPTIIESVSFRAW
LEEAFSIWSEWRHIYPPRSATADLLGRIRDDYWLVNIIHHDFVEKDALWRLLFED
>A0A837B0X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaesserella parasuis HPS9|TrEMBL
MSYAKEIDLLNQSVADLNGKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERNRTHSIVKTIQQETGIVAAPHLTGIDATPDELRAIAKDYWDSGIRHIVALRGDEP
AGYAKKPFYASDLVKLLKEVADFEISVAAYPEVHPEAKSAQSDLLYLKQKIDAGASRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMAKMYQGL
DDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGVRPE
>A0A1V3FXG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus karvacharensis|TrEMBL
MGLLNDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIDAGAEIIQTN
TYGANYVKLARYGLQDDVKKINEAAVSLAKQAAKGRAYVLGTIGGLRSTNKSTISLEEVK
RTFREQLYVLLNENVDGLLLETYYDFEELQTVLSIARQETTLPIIAHVTLHDIGVLQHGM
PLADALYQLEQLGADVVGLNCHLGPYHMLRSLEEVPIPSRAFLSVYPNASLPQYRDGRFV
YETSEQYFEETARAFRDQGVRLIGGCCGTTPKHIAAIARALSDRTPVYKKEVKQRHTITV
QEAEQTSAPSLADIARMRRSIIVELDPPKKLGLTKFLEGAKALKEAHIDALTLADNSLAT
PRISNVAVGTIVKQQLNMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRL
EKKIECGAHYFLTQPLYSEKQIEDVYEATKHLSTPIYIGIMPLTSARNADFLHHEVPGIT
LSDDIRARMAACANDPIQATKEGLAIAKSLIDAAFDLFQGIYLITPFLRYDMTVELVRYI
HEKERLAKERTVYYG
>A0A3G4YVG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niallia circulans|TrEMBL
MNFLDRLKNEILIGDGAMGTLLYSYGKDTCFESLNLSHPEQIEQVHQAYIHAGADIIQTN
TYAANYLKLQRYGLEDNVKEINSAAVKIAKKAVENKNVNVLGTIGGNRGMKPQAISLEEL
KRSFREQLYCLLLEDVDGILLETFYDLEELETVLEITKKETDIPVLAQLSIHEIGILQNQ
ISLASAFDRLENLGADIIGLNCRLGPHHMIASLEQIPLPRNAYLSAFPNASLPSYIDGKF
EYKDNAEYFQRSAEEFRKQGVRLLGGCCGTTPEHIRNFAKVLKDASPITEKTIETNKAVV
DSILEHSPPPRDYTPLEEIVKTRASVIVELDPPRKLDTTRFFEGAKKLKEEGIDALTLAD
NSLASARISNTAIATLVKQNIGLRPLVHIACRDRNIIGLQSHLMGLHTLGIHDVLAITGD
PARVGDFPGASSVYDMTSFDLISMIKQLNEGLSFSGKNLGQKTTFSVSAAFNPNVRQVEK
AVKRLEKKIECGADYIITQPVYSEQKIIELYEATKHIDTPIYIGLMPLTSSNNAEFLHNE
VPGIKIDDSIRRTMAQFKDNPVQAAQQGLKITKSLIDTAANYFNGIYLITPFLRYELSVE
LARYTKLRTAALRRTTDATNFIS
>A0A7D5R217|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas yamanorum|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKSAGIQRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A2C9WH12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Manihot esculenta|TrEMBL
MKIIDKINAATGGVGLPDGHSNGGAEPNNNRVVFSFEFFPPKTEDGVDNLFERMDRMVSH
NPSFCDITWGAGGSTADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGI
QNVLALRGDPPHGQDKFVQVEGGFACALDLVKHIRSRYGDHFGITVAGYPEAHPDMIGSD
GLATPENYQKDLEYLKRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGIKCPIVPGIMPI
NNYKGFLRMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGVHLGTEMCKKILAHGIKTLHL
YTLNMEKSALAILMNLGLIEESKVARSLPWRRPANIFRVKEDVRPIFWANRPKSYISRTL
GWEQYPHGRWGDSGNPSYGALTDYQFMRPRARDKKLHDEWATPLNSIGDISEKFKRYCLG
KLKSSPWSELDSLQPETKIINEHLGKINLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYV
YQKAYLEFFCSPDKLQILVEKCKSFPRLTYVAVNKGGNLISNVGSNDVNAVTWGVFPAKQ
IIQPTVVDPASFFVWKDEAFEIWSRGWASFYPEGDPSRKLLQEVQSNYFLVSLVDNDYIH
GDIFAVFADL
>A0A399ELQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calidithermus terrae|TrEMBL
MKISALLRATQPVFSFEFFPPKTPEGEQQLFQTIAELRPLSPGFVSITYGAGGSTRKRTV
EWVRRIRELGLEPLAHLTCAGSSREEIAALLEELATCTDNVLALRGDPPKGATAFVPAEG
GFRYANELVAFVRERQGDRFALGGAAYPEGHPESVSLEADLQNLRRKVDAGLDFVITQLF
FNNALYFGFVERARRAGVTVPILPGLMPVTNLAQVRKFMDLCGASIPGPLLSRLESVADD
PQGVLEVGVEHATKQAAELLAAGAPGIHFYTLNKSPATRRVLENLR
>A0A3A5TJF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AM37-9|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A4R8VTC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. MDB2-B|TrEMBL
MSTPSDSARTRRIPFSFELYPPKTDAAAAALATTIDHLAAAGPDFLSVTYGANGSSRRSS
LDVLSRILRTTNVEAMAHLTCVGSTHEEANRLIREFLDAGVRSFLALRGDPPAGTKEGEA
FLGDFGSAAELVQLIHRVQAEKSPYRETIIPGIPAARAVKPGHEKVRIAVAAFPNGHPRS
RSSAQDIDTLLAKQAAGANLGITQLFFHADHFLSFVQRAREAGVLFPILPGIMPVTSPAR
LRRIIELSGEQMPADLSIRLEIEPTREGQREIGIRHAVDLATQVIAGGAPGLHLYAFNQH
ETVLEVLDGCGLLGATAPVRDTPAQPQAPAPTALPTIV
>A0A1F9H6K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFCSPLOWO2_02_FULL_40_36|TrEMBL
MNFKDFYQDQKVKFSFEVFPPKTEEGVRSLFSELNQIQNLNPAFISVTYGAMGSTRDLTR
DLAIKIKKELGLTTAFHFTCVGSTRKSIKEYVEHLKKEGLNLVVALRGDAPQKTNKFTPP
LHGFSYANELVDYLKQINGFSIAVAGYPEGHIEAPNKNVDLENLKRKVDAGADSVITQLF
FDNKDYFDFVNRARKIGISIPIIPGILPILNVKQVERLAGLCGAKIQANLHQKLLQCGED
ILAMREIGIEHATTQCQELIKKGAPGIHFYMLNKAHSVEKILANL
>A0A5C7F4C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. BA40|TrEMBL
MTIAQIFERAQHDGTLPVSFEMFPPKGELSLERAREVAHAFAPLAPDFVSVTYSAGGSGN
NAATTHIARMINDELQTPSVAHLTCISLKRADLAAKIEEMRGAGIRNVLALRGDVPDGAP
TGPGCADYRYAKDIIPALVDAGFCVGAAAYPEGHIECDDPALSIQRLKQKQDAGASFLVT
QLFFDNQYFYRFRERAAAAGIAVPITAGIMPFMSKQQITRMVFMCGASLPSPVIKLLARY
ENDPASLRAAGIEYACRQLEDLAAHGVDGCHVYTMNRLDVARAAMSALRR
>A0A1Y3QA12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermobacillus sp. ZCTH02-B1|TrEMBL
MRPVLRDALRTSVLTGDGAMGTYLHQLGHPIGVSYEEFNMTRPETIAAVHRQYYEAGARV
IETNTFSANAERLARYGLEDEARRINREGVRIAREAVGADAWVVGAVGAIRAGRLRAVGL
PAIERALAEQIDALLEAGVDGILLETFYDLDELLLALRLVRQRSDTTVICQLAAVGTELL
YTGLPIAEAFRRLEAAGADAVGFNCESGPNGILHAIEALGGAVNLPISVYPNAGGADYVD
GRITYAAGPAYFGDCAKRFAGLGARLIGGCCGTTPEHIRAIASALAGMAQDGAPAGGQAR
AAAMRDAGAKAADAAPAAESRPRIRVTAEPAPSAPGGEAPGGGDDPTLVELVRRRPTVIV
ELDPPRDLDITKFMAGARALRDAGADALTMADNSLAVTRMSNLALGAIVKERVGIRPLVH
VACRDRNLIGTQSHMMGLHALGIDHVLAVTGDPAKFGDLPGSSSVYDLTSFDMIRMIKQL
NEGIAFSGKPLRQRARFIVGAAFNPNVKHLDKAVRRLEKKVECGADFIMTQPVYDAALIE
RIADATRHIGVPIFIGIMPLASGRNAEFLHNEVPGIELSDEVRRRMAGLEGEAGRAEGIR
IAEELLDAALQFFNGIYLMTPFMFYDMTVRLTGYVRAKARLETCEISCSSGKNELK
>A0A838NQ50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
VDSKMPVVAQMTIGTDCHTPYGASAEDIATSLDAFGADVIGLNCSVGPQIILDAIEKMVK
VTRKKLVAQPNAGMPREVGGRSMYMASPEYMATYAGHLVRGGARIVGGCCGTTPEHIAAM
VEGIRPLSPRQARVPVRAPARDGATLPPEDKGVAPVPFEERSRFSGKIARGEFVTSVEIV
PPRGVDASKMLRDTEALKAAGIDAVNVPDGPRAQSRMGALLTSLLIEQRVGIETVTHYCC
RDRNLLGMLSDLLGASAIGLRNILLITGDPPKMGPYPNATAVFDIDAIGLTNLVNKLNHG
LDPGGNAIGAPTSFAIGVGVNPGAIDFAHELKRFAWKVEAGAEYAITQPVFDVEQLERFL
ASIDGSRIPIIAGIWPLLSLRNAEFMANEVPGVVVPGHIIERMRQASARSKEHGLQEGIA
IAREMLERVRPSVQGAQVSAPFGKVELALEVFGETMSAASV
>A0A7X8LF73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierellia bacterium|TrEMBL
MHISKLFKDKVFVYSFEIFPPKAVYPIDSIYTTIDELSELKPDFISVTYGAGGSITNNRT
AEIASIIKNKYSIEALAHLTCINSTQEQIDHVIKDLKKKGVENILALRGDIIEGGEPLGI
FKNSQEIIRYAKENSNFGISAACYPEGHMESKDKSIDLEILKLKEEAGAEHFMSQVFFDN
KYFYDLLDKAEKKGIKSPIQAGIMPVINKKQIERIISLSGCTIPEKFIKIINKYEYDKVA
LRDAGIAYALDQIVDLISSGVKGVHLYTMNNPYIAKTITNSISSILASVNNQD
>A0A7Y8JI55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilaceae bacterium|TrEMBL
MATPTYSFEFFPPKTPEGMEKLRATREKLAALKPKFFSVTFGAGGSTRDRTLETVLEIQQ
QGYEAAPHLSCIGATREDIRAILQTYKQHGIRRIVALRGDLPSGMAEPGELRYAGELVEF
IRSETGNTFHIEVAAYPEIHPQAKNAQDDLKNFAGKVRAGADSAITQYFFNADAYFRFVD
EVHALGVSIPIVPGIMPIGNFSQLARFSDACGADIPRWIRKRMEGYGDDSESIRAFGLDV
VTDMCRRLLAGGAPGLHFYTLNQAELSLEIWKRLGL
>A0A084T376|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. ER1A|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSTPTMEETLWKSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSETGLVAAPHLTCIDASRDELIDIAEDYWSNGIKNIVALRGD
IPAGGGQPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAGMNKVKVPGWMQKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQV
>A0A436JBI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.03.2.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>V8D3Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia sp. D3|TrEMBL
MDTTTDGPDAFTEYRGTRSRECPKRMVFGPCGGVRDDATCEMDAHICPFAVLTEPIPWPQ
PLTSPASPSELINASRTRPVVLSDLSVPAFDRGVLEQVASILGESSDAVLVGEHQNRPDY
PPTVMAQIIRGVGGCPWVTLTCRDRNRVVLEQELMGLGQAGADGVFCVTGDGRAQGVRQD
VTQVFDLDGTRLAALAAQADLAVGVPEAPEAVPTSIRPARLLEKQRAGAQLAVLNHVSTP
DSLRAFMSAARAQGVTMPVIAGVAVYTDERSAQVLAAFPGLHLDHSQITRVLAADDSVEE
GIETAVVEAVALLDIPGVVGVNLSGLASAAGEVPAAKVKAEIGRRLRERLADGAQSVKAA
QW
>A0A2D0KG16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus ishibashii|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEQTLWKSIDRLSKLRPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLDAAPHLTCIDASREELSNIAHDYWQNGIRHIVALRGD
LPANGCKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFASMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A5M8QPD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrococcus sediminis|TrEMBL
MSALPYSFELFPPRNDAAAVRMLEAVDAFAAVEPAFVSVTFGAGGTTSRHSLGVLQRLLD
AGVSPMAHLTCTGLGVSDTARLVRQFLDAGITKFLALRGDPPADGVPEPATSLRSAAELV
QLIDRVDSERVPYAEVPLPGLRASALAERRCGVEIAVAAFPNGHPGAGVHRGDVDALLAK
QEVGATLAITQLFHDPYDYARYVELARARGVTIPIVPGVVIPTSHRRLVRSAQLAGEGLP
RVLAERLERATPDEAVAIGVDAAVALIDSLAEHDPPGVHLYTFNDHRPAIDVLHGIGALA
PTRTITTGAP
>A0A5Q3Q7U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allosaccharopolyspora coralli|TrEMBL
MDATSTQQLRSLLGRARFEVLPTHGVLDRVDALPTGTTVTVTSSPSRGPETTVDVAEDLA
ARGMHAVPHLAARQVVGTSQLSSLLDRIHDAGVSEVFVIAGDGPTPAGPFPDALALLRAI
TDSGRRPSRIGITGYPERHSAISDEDLVEAMERKSVHADYVVSQICYDSQTIGDWLTAVR
RRGIDLPVYIGIPGSVDVTRLLRISLKIGLGDSMRFLRKQRGGLGKLLSRYTADDVVEQL
SPYLLEPWYDVAGWHLFTFNEVATTARWRDDLAARIEEVPA
>A0A2P5TI76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanisphaera arctica|TrEMBL
MGFHSARHVEALNQSMAELNGDINVSFEFFPPNSEQMEQTLWSSIERLKTLAPKFVSVTY
GANSGTRDRTHKVIKDIQDKTGLIAAPHLTCIDASRDELRGIARDYWNNGIRQIVALRGD
LPKGIDKPDMYAADLVSLLKEEADFDISVAAYPEVHPEAKSAQADLLSLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTIGIDVEIVPGILPVSNYQTLIKFAGFSNVRIPGWMHQRYQ
GLEDDQNTRNLVGASIAMDQVRVLSREGVKDFHFYTLNRSELTYAICHSLGVRPPVAVAS
>A0A496SZQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MNQQKSFKAGSRLEKVLLSGHFAVTAELGPPKSADLELVRRKIGYLKSYVDAANITDNQT
AIVRLSSIATATVLCQNGLEPVIQMTCRDRNRIAIQSDILGAYALGIKNILCLTGDHQSL
GNHPGARGVFDLDSIQLVQMLKVMRDEKRFLCGEEIRNSPKAPVVEPRMFIGAAANPFGD
PFELRVVRLAKKIAAGADFIQTQCIYDMKRFRQWMQQVQDKGLHQKVHILAGLTPLRSVR
MAQYMKQSVAGVTIPDEIIQRMAQAKDPAEEGVKICVEQIEELKEIEGIAGIHLMAVAWE
KIVPVIVERAGLMPRPSV
>A0A5D2F2N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Darwin's cotton|TrEMBL
MKVIEKIQSLQEGKAVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNELAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGVKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQYPYGRWGDSRNPS
YGALTDHQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSYCLGKLRSSPWSELDSLQPET
KIIHEQLGNINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGTTDVNAVTWGVFPAKEIVQPTVVDPASFMVWKD
EAFEIWSRAWAALYPEGDPSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>A0A5D2F2N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium darwinii|TrEMBL
MKVIEKIQSLQEGKAVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNELAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGVKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQYPYGRWGDSRNPS
YGALTDHQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSYCLGKLRSSPWSELDSLQPET
KIIHEQLGNINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGTTDVNAVTWGVFPAKEIVQPTVVDPASFMVWKD
EAFEIWSRAWAALYPEGDPSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>A0A1W6MJZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonlabens spongiae|TrEMBL
MRITDHLKKADKPLFSFEIIPPVKGKSIKELYDNIDPLMEFKPPFIDVTTSREEFIYIEK
ENGLLEKRLTRMRPGTLGICASIQNKYGIDTVPHILCGGFTKQETEYLLVDCMYLGIDNV
MALRGDARKEEKRFSKTEEGHEFAIDLVKQIQAQNKGKYLHEVIEISCDVDFCIGVAGYP
EKHEESPSLKSDLKRLKEKVDAGADYVVTQMFFDNNKFFEFVEAARAMDINVPIIPGIKP
IATKKHLNILPQTFHLDLPQELVDAVESCKNNKEVRQVGVEFAVQQSKELLEYGVPVLHF
YSMGKSDNIEAVARELF
>A0A246GDQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium columnare|TrEMBL
MKVTEHIEKAKGKTQFSFEILPPLKGQNIQCIFDGIDPLMEFNPPFIDVTYHREEYEYKE
LQNGLLQKKIVKKRPGTVGICAGIQNRYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGNAYASELVAQISNLNNGIYLDSDLQNTNTTDFCIGVAGY
PEKHMEAPSMDSDIHFMKQKIKNGADYIITQMFFDNQKFFEYVEKCRNAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNEAVKQIGIEWCIQQSKELVKAGVPFLH
YYSMGKAENIKAIAEEVF
>A0A660Y476|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MKTKSNLERVLEAGHFAVTAELGPPRGADPEAVRKKAKILKGYADAFNVTDGQTAIVRMA
SWAACLVAKEEGLDPIVQMTCRDRNRIALQMDVLGVAALGINNILCLSGDHMSFGDHPGA
KGVYDIDSVQLVKMVKDMRDEKKFQCGEEMEVEPRLFIGAAANPFAQPYDYRPYRLAKKV
AAGADFVQTQIVFNLDRFKEYMKRVCDMGLHEKVYILAGVSPIRSYGAAKYMATKVPGLD
VPEEILERMRKTPKGERAEEGKKICVEIIQQVREIPGVRGVHIMAIEWEEAVPEIVERAG
LLPRP
>A0A374BW19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM43-6|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A1H3YPJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium NK3A20|TrEMBL
MKVIDILHEKDVTISFEVFPPKTDDKYAQVEEAARKIAALAPSFMSVTYGAGGGTSQNTA
AIAADIQNTTGTPVLAHLTCVSSTKDHVRRMIRVYKESGIENIMALRGDIPKEGRTVFDY
NHASELIYDIKSQDASFCIGGACYPEGHVECERPSEDIAHLAEKVAAGCDFLTTQMFFDN
NTLYNFLYRIREKGINVPVLPGIMPITNKRQVARSISLSGATIPQRFRMMVDRFGDDPAK
MKQAGVIYATEQIIDLISNGVTHIHVYSMNKPDVAAGIMNSLSEILKS
>A0A0C1DCP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter kyungheensis|TrEMBL
MKITDHIKNAKGKTLFSFELLPPMKGQSIQWVYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARQAEASFIPTKGGHHYATDLIQHIKDHNNGKFLHEDIDTYKSDFCIGVAGYP
EKHFEAPNLNADFKYLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLKQLTVLPKIFHLDLPNELTEALSHAKNNAEAKEIGTEAMIKQCKELMDFGAPVLHF
YTMGRPEQTKEIARAIF
>A0A2D4SF82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinisphaeraceae bacterium|TrEMBL
MTQHPNAFSFEFFPPKGPKGADRLGRVRRELAALGPKFFSVTFGAGGSTQAGTRETVAAT
RRETGIATAPHLSCIGTTRARIRDLLEDYAALGVDRIVALRGDVVPGQTETGEFAYASEL
VAFIREAFGDRFHVEVAAYPEFHPEAPSPEADIRHFVTKVKAGADSAMTQYFYNADAYFH
FVDQLEKAGVDIPVVPGVMPLANFRQVARFSELCGADIPRWVRLKMDSLADDPAAQTDFA
EEVVSRLAQRLLEAGAPGLHFYTLNQARPVQAIWKNLALPMQD
>A0A6G6RGR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. 'scallop'|TrEMBL
MASSASLNLADARALLLSPLGPVARAGSNRDAVRVSFEFFPPKTDEAEANLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTNRTVQRIITETSLRPAAHLTCVEASREEVDEVIEGYKAIG
VDHIVALRGDPPGGAGIGGVYQPRADGYANATELTAAINRIGGFDVTVGAYPERHPESPS
IDHDIEVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVIIPLIPGVMPVSNFTGLQ
RMCGACGASIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETATA
>A0A2W5YCN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dormibacteraeota bacterium|TrEMBL
MVVNKLAQRLERGPLLFDGAMGTEIYARGVAEAECLEALNVSQPALIARIHRDYIAAGAD
VIETNTFGANRFRLGEHYREAEVRQLCLAGARLALEARNAAGRPVLVAGSVGPLGRPIEP
VGAIKRSGAERVFSEQIAALAEGGVDLLILETFTALNELELAVDAARATAPDLPVVALLS
FDDELNPARAASALVESLSARGVTALGANCGAGPQSALSVARQLASLGAQRLAILPNAGL
PHREAGRLVYSAGPQYFAEQMAELLELGVSVVGGCCGTGPAHIQALRRRVDGAAPGRTVS
PRIRRAEPGERQVEAPSTSLAAKLRAGEFPISVELTPPRGIDPSRMLAGARLLQEAGVEF
ANVTDSAMARLRMGVISCAALVQQQVGLETIAHFTCRDRNVMAIQSELIGAHALGIRNIF
ALRGDPPRVGDYPKATPVWDVNAVGLITILSNLNRGLDANGTPIGERAFFNIGAAFNPTA
EDPLKELRLLRRKLAAGAHFVLTNPVYDFAALALLRQVFQEVEVPLLIGAMPLRSAKQAA
YLQNEVPGIVVPETVAKRLEAAGEEAPQIGVEMAIAFFEELAGVAAGAYVIPSGGRYDLA
AQVVEGIKSHRS
>A0A7V7BFQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MENRFKNSLLDKSTVSVTWELVPGRGAKEPQQEFAVQAAEQAAKGGKVHALTITDNPGGN
PAMLADYLGMEVFQKGIEPLVHFTCKDKNRNQMESQLYALDRAGVRNLLVMTGDYPVTGF
KGRPKPVFDLDPVHVLELIEEMNKGLEYPGMKGTIKHQPSDFFAGAAVSPFKATEAEQMV
QYYKLKKKLDAGAKFIITQVGYDARKYHELLLVMKQLGYEHIPVVGNIYVLPYGAAKTMN
ANRIPGCVVTDKLLA
>A0A7V6GCK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MENRFKQSLLDPNTFSVTWELVPGRGAREKSQESAIAAAEQAAKGGKVHALTITDNPGGN
PAMLADYLGAEILKMGIEPLVHFTCKDKNRNQMESQLYALDRANVRNLLVMTGDYPVTGF
KGRPKPVFDIDPTHALQLIQEMNKGLEYPGLKGTIKHQASDFFAGAAVSPFKATEAELMV
QYFKLKKKIASGAQFIVPQLGYDARKFHELIQFMRLNDLNVPVVGNVYILPYGAGRAMNQ
NQVPGCVVTDKLLAVLDKERQAPDKGLGARLLRAAKMYAFMKGMGFAGVHIGGHNIKYEQ
VEYIIEKGEELSKNWMDYIHEFDFPMENGFYYYQKDEKTGLNTEIPTERKGRPLDTKVEF
TYRLSRVVHSLIFEPGKNFFGLMKGISKAVEGKKIEKLYHGIEHLGKVAIYDCKDCGDCA
LIDLAYVCPMSQCPKNQRNGACGGSYNGWCEVYPGKKKCAYVRAYSRLKNYNQESELDSY
QVDPCNWDHYQTSGWINYYTGKDHSAERLGLNKDRKKAPSDGKSVSK
>A0A7T1HL19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. CBW1107|TrEMBL
MLLRQALETGQFAITAEVTPPRGGDPTRTLTVAAKLRGLVHAVNVTDGSRAVMRMSSLAL
CRLLLEAGIEPVLQLACRDRNRIALQADLLGAHALGIRNVLCLTGDPVGAGDQPGARAVN
ELESVRLLQLLGRLNAGLDPVEGVLPDGPTALFPGAAADPQSTSWSGLRARVARKQEAGA
RFLQTQMVMSTEALRRFCGEISEPLGLPVLAGVFLLKSARNAAFINRVVPGASIPQPIID
RLAASADPAAEGVAIAAEQVRAYRAIAQGVHLMAVKAEERIPWILAEAGVSPPGGAVLTE
VSSHPH
>A0A838PET4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MRIDEVLVEQRPVFSFEFFPPKTDEGYENLRATLDALRHDRPHFVSVTYGALGSTRDRTI
DLVKEIEQQLGIEAMAHFTCVGAATDELRATLREIEDAGVANVLALRGDPPEGEDVWTQT
DGGLRYSTELIELLSGEFDFSVGAAAFPEVHPEAESAEHDLRFMKAKQDAGASFFITQLF
FDNEFYFDFVARAREAGVTVPIVPGIMPVTNYRSIKRITELCKSEIPEPFERELEARQED
ADALADLGVAYATLQCVDLLSRGAPGIHFYTLNRSPATRAILAALRAAQPWTRAAQPV
>A0A7X8Z5K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MVTTKMNKDFIELVTPKQSTTDLEGEMEKFAERYRLFLENDMVISITDNPMSNISYMGTE
MIEALELPVEPENIIPHLNTFHRKTEEKYDPGKDQNEQDFNILVEHAAALGIKYLLCVSG
DGNERLPRLQPEDLGYDPAKVKTITSVQLLEYLNRAYPGVFTMGVAFNQYEPLAAEMEKL
RQKTAAGAAFIITQPVVLTESGDPALTTANNNLRQMLKYADDQGIQVILGVWMSAKLAYL
IPECIGFDVDFGNFSPDENLKVIRETYPGRRFYYSMVLTAKRLQDVQAIAGNR
>A0A4R2D6L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella granuli|TrEMBL
MAHIDENPLGPHLPLDPLPGHSSLGRLERVLRRGEFAVTTELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGV
GPMASAKTAKWIRSNVPGIHIPDSVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEIVHDSGVLKGRQPWKREPNPVDQLVAERIERTRQGVEQNQQQMAETAA
HHPH
>A0A7C6RFM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MLKNENLCTKLKKRKFVVTAEISTPKGVDITKTIEEARKLKGIVDALNITDCPMANMRMS
PIAVAHLLQDHLNIEAIFHLTCRDRNLIGLQSELLGAYALGVRNILALRGDDPSRGDTPQ
AKGVYDVDSVGLLKIISAFNRGYDYNGNKLDSPTEFCAGTTANPNDLRDEALEKLKVKIE
AGAEFIQTQPVYDEEILFKFIEKIKNFNVPLLIGILPLKSYKMAVNLNEKVPGIDIPEKV
LERLKDGGREEGINIAVEFIKRIRSEVAGIHIMPLGSTNVVLEIISRVDDLVCDFAENNV
QMN
>A0A7X7RUV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MNFEEKLKSGKMVITSEIGPPKGTNIMPHIKEAEGIKDKVDAFNVTDLQSSVMHLGSLAT
SRLLAERGLEPVFQITCRDRNRLALQSDLLSASVLGIRNVLVITGDHTVLGDHPQAKPVF
DLDSVSLLKVASGLMKGKDMVGNELDGIPEFFLGAVVNPGYEPQELQIMKMEQKIEAGAR
FFQTQAVYDLTSFESFMKRVLPFGAPVLGGIVLLKSAGMAKFMNKNVAGVNIPDKYINMM
AAADKKDRPKVSISIAAELIKGMKTLCSGIHIMSLGWEKYIPDVLEASGF
>A0A847AYL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MRIPELYKIKKPVFSCEVFPPKPEYPLDTIYDTISKIRNLEPDFISVTYGAAGGTRERTE
EISTEIKKKYGLETLMHLTSINSTRNEIESIISEIRESGIENILALRGDIHKDADKESLS
VDFNFASDLVKYIRQKGGFSIGVAGYPESHPESPDVKTDIVRLKEKVDAGADFIISQMFF
DNPLFISFMERVRSAGIDIPVSAGIMPVFRAGFVVNIVNLSNATIPPDLRVLIEKYGDNP
EDMEKAGIEYSCRQISGLMENGVDGIHLYMMNRANLATEIALNTGLRKIEGNKKNE
>A0A7C3NWK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MQSQRKFPRAFSFEFFPPKTPAGKVKLRETWQQLGQLKPKFFSCTYGAGGSTREGTLETV
LEIRAAGHEAAPHISCVASSRSDVKAQLERYRSHGIRHIVALRGDLPSGLASLGELRYAN
ELVAFIRETTGDWFDIEVACYPEFHPETRSAADEIRYFKRKVEAGANGAITQYFYNADAY
FRFVEECEAAGIDIPIVPGIMPIGNFAQLARFSDACGAEIPRWLRLRLESFRDDTASIRA
FGLDVVTRLCDDLLRGGAAGLHFYTLNQAGLTTTIWQRLGL
>Q5KN82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)|TrEMBL
MPHLTSLIAAHNGPFHNYEFFPPLTDPGFVNLLDRIRRLTSSPFQAPLAVSVTWGAGGST
AEKSLELAQQVVDMGVEVILHLTCTNMPKDKVDFALRRCKDLGISNILALRGDPPREEEY
AINPTSTPDFFKHADDLVRYIRQTHGDYFCIGVAGYPNPHPDSESEEEDFKWFKAKCDAG
ADFIVTQLFYDVDVFLEWVKTCRARGINQPIIPGIMPIQNYASFRRLVNLTKCPVPDSIT
SDLQPISSDDATVKRYGAELATKMVSQIIESGLVPGVHLCTLNLEKSVRMILDNLGWSAA
SKTSEDEGLVKNKLIEDDGQARKGIPINGKAGTAQSPAKNLSISPSEANQLAQLGLTSTT
LPPAPKTGLSAQGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKEWGVP
VSTSDLSALFTAYLHSDPKHLTTPFCDLPLSPESHMILPHLLALNSANVQHWTVGSQPAV
DAAKSEDEVVGWGPRGGYVFQKAFVEFFVTEDEVNRLKEKVEREGKGLITMYAANRKGDF
KTNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWAEWSLLYPRNTPSRKL
LEGIANEWWLVSLIHHDYKDQGALWRFLLEDLQ
>A0A536TC79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTGSVDRIFSCEFFPPATPEGVAKLRATREQLARLGPKFFSVTFGAGGSTRDRTLAAVLE
IQASGQRAAPHISCIGSTRESVRSTLQTYREHGIGHLVALRGDLPSGSADVGEFRYANEL
VEFIRDATGDWFHIEVAAYPEYHPQARTPHEDLASFKRKIDAGADSAITQYFFNADGYYH
FVAEALAAGVSVPIVPGIMPILSFSKLARFSDACGAEIPRWIRRKLESFGDDTASIRAFG
LDVVTRLCDDLLGHGAPGLHFYTLNQASLTTIIWQRLGLS
>A0A416K503|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium AF29-16BH|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGKDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKAAEI
>A0A2V2C7M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MSVAEIYEKRATFSFEVFPPKTDVGMEKLCGEGGVLEKLYTLNPDYISCTYGAGGTNVGK
NLEVLDKIVKDGKTTPITHFTCIGNTKEDIKEKLQTYLDHGINHMLALRGDLPFGWTGTN
GDLHYATELVKFVRKEFGDKFTIAVAGSPEGHIQCRSLEADIAFLKQKQDNGADFIISQL
CWDMDAFRYWLDAIRGAGIWLPVDVGIMPILDQAATINMALSRNGCVMDRKLCEIISKNW
IFPNPFDKEPFDADVAGKKASFKAAGIEYTINQIDEYRACGVDGIHLYALNKYDDVANIA
KLAGLIDLV
>A0A536Y0D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MSFPASATEPGIEARASELVAAGSVEISPRELHRATEVAALLPAGSCVYIPSLAGLPLAR
TLEAIAAIRAAGLDPVPHVSARRIVNREEFRDFLRRAAAEHGVHRVLLIGGDEPRPKGPF
VDSLQILEERLLADCGVREIGLAGYPEGHPRIPLNAIEAALARKLELAAAQSIGVYVLTQ
FSFAPARVVEYCVMLARRWPSLPVYVGIAGPTDPAALARYAQRCGVSRSLRALRTLGSGI
AQLVTNTDPRDQVVTVARYTRSREPSNVVGVHLYSFGGAVRTAAWMRELL
>A0A562FRE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter sp. J15|TrEMBL
MAANQFFSRRTDLGARIKVSFEFFPPKTDEMEQRLWDTITRLEPLDPQYVSVTYGAGGTT
RERTARAVDRILRESSLKPAAHMTCVDASRAEVDAVIAEFVAMGVKRFVALRGDPAAGVG
ARYQPHPDGYQNGADLVAAIRKQGDFDVSVSAYPEKHPESADFATDIDMLKRKVDNGATR
AITQFFFDNDLYERYVERVRRAGIYIPIVPGVLPIHNFQQVANFASRCGTHVPEWLAERF
AGLESDPQTHALVASAIAAEQVLDLVERGVEEFHFYTMNRADLAFAICHLIGIRPHVRTT
QAKAA
>A0A1C4Q125|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ScaeMP-e83|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRIESVRPSFVSVTYGAGGSTRSGTVRA
TQQIAADSTLTPVAHLTAVSHSVAELRNMIGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFSQLSNATVPEPLKERILAVKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A536SPI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MESQKKHPRAFSFEFFPPKTPEGMERLRATWKQLAQLKPRFFSCTYGAGGSTRDRTLETV
LEIQAAGHKAAPHISCIGATRADIAATLELYKSKGIDHIVALRGDLPSGAASAGELRYAS
DLVAFIREKTGEHFHVEVACYPEFHPQARSPREDIANFKRKIEAGADAAITQYFYNLDSY
FRFVDDCEALDIDLPIVPGIMPIGNFSQLARFSDACGAEIPRWLRLKMQSFGDDAASIRS
LGLEVVTDLCDRLLSAGAPGLHFYTMNQAGLTSTIWQRLGI
>A0A3C1ELP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MKIAELFGRPDPVFSFEFFIPKTPGETDAFLANVRALQALKPAFVTLTYGAGGSARERTI
ELAGRMRNEVGTETVCHLTGITHTRAEMSRNLERLRALGISHVVALRGDRPKDWDGELPG
DFPYALQLVEFIRRAGGFHMAVAGYPEGHPEAVDKSDDLARLAAKVRCGGEWIITQLFFD
NRHYFAFVDAARRAGITVPIVPGLMPVTGFAQLKRFTSLCGASIPPEMAADLERIHGDGE
AVVRYGIDWATRQCRELLERGAPGIHFYTLNRSRSTAEILSALRKLN
>A0A433VYE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroococcidiopsis cubana SAG 39.79|TrEMBL
MHNTTRLNSFRKAVKAREFLVTAEVAPPKGGDPSHMLQMAQALKGRVHAVNITDGSRAVV
RMSSFASSVILSQQGIEPICQVACRDRNRIGLEADLLGAHALGIHNILALTGDPVKAGDR
TDAKSVFDLESVRLLQLIGKMNQGLDCDDKPLTDGATDLFVGAAVDPQCKSWSGLQSRFE
RKLAAGAQFFQSQLITDFDRLEKFMTQIAGGCNKPVLAGIFLLKSAKNAQFINRCVPGVN
IPEHIIDRLAQAKEPLAEGVKIAAEQVQIARQLCDGVHMMAVKREDLIPQILDLAGIPPV
VSYSLPSQVVSSLR
>A0A536UTC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTGNADRCFSFEFFPPATPQGVEKLIATREQLAQLRPQFFSVTYGAGGSTRDRTLETVLD
IQKSGQRAAPHISCIGSTRESIRETLATYREHGIGHLVALRGDLPSGSVDAGDFRYASEL
VEFIRSVSADAFHIDVACYPEYHPQARSPADDLASFKRKIDAGASSAITQYFFSASSYYY
FVDDAAALGIQVPIVPGVMPIASFSKLARFSDACGAEIPRWIRKKLESFGDDSASIRAFG
LDVVTDLCADLLAHGAPGLHFYTLNQASLTTIIWQRLGLS
>A0A536SDQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
DVASIRSLGLDVVTDLCNRLLSAGAPGLHFYTMNQAGLTSTIWQRLGI
>A0A536XVP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MVAERRAASELQAKLRSGQFVITAEITPPVSTDPAEFLRRAMPLKGLATAVNVTDGAGAK
VHLSSLATAHFLVQSGIEPIFQMTCRDRNRLALQGDILGAASLGIRNILVLGGDDPKAGD
QPETKPVYDLDSRTLLAMAHRMRTENALPTGTKIDGPQLRLVLGAADVPLDPPPGWEPNG
LKAKIEAGADFVQTQFCMDVGVVRRYLQRLADAGVRVPLLIGVAPIPSARSARWMREKLY
GTIIPDAYVERLERAADPKLEGRKICIEVLRELAEIPGVAGAHVMAPMNFAEIPVVITES
GVAGRRLAHAVH
>A0A2H5B3F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora sp. MMS16-BH015|TrEMBL
MFRSEVGEPSYSFEFFPPKTPAGELSLWRTIRRVEAVAPAFVSVTYGAGGSSRERTIETV
ERIASETTLRPVAHLTAVGHSVRELRSFIGQLADSGIRDVLALRGDPPGDPGGPWVRHPE
GFAYAADLVRLVKECGDFTVGVAAFPERHPRSESWDEDIRHFVAKCRAGADYAITQMFFR
AEDYLRLRDRVAAAGCDTPIIPEIMPATSFSQIARFAALSNATLPPELARQLEAAAGDPG
AGHRIGVDHATAMAAELLAEGAPGLHYITLNSSTAAVEIHQNLGLHRAPSILTAV
>A0A5D4FRP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium urealyticum|TrEMBL
MSTMISFMSASNPHDHHEKASPLPGIPPQPTLQVPVSQAIRGYSPGKIPFSVEFMPPRDD
AAQTRLWNAAEAFHDLGVSFASITYGAGGSTRERTMEVAQQLAAKPLTTLMHLTLVDHSA
EELRAMLQDYARRGMTNVLALRGDPPGDPLGTWQPTPGGLNYASDLIELIRNTPECENFD
IGIASFPEGHYRAEDLEQDTQVTLHKLRLGADYSITQMFFDVENYLRLRDRLAAADPVHG
AKPVIPGLMPITSIRSVRRQMELAGGEVPVKILERLEKAAAGDEVANRDAVREVGIDITT
EMSERLIAEGAPNLHFMTMNNVRATQDVLHNLGMAPAWGPGYGQDMVR
>A0A537G786|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MASNLLTRLQSGDFVVTAEITPPVSTDPAEFISRALPLKGLATAVNVTDGAGARVHLSSL
AAAHFLVQNGIEPIFQMTCRDRNRLALQGDLLGAISLGIRNVLCLAGDDPKLGDQPEAKA
VFDLDSRGLLAMAHRMRTEQRLPSGTEVKGGVRLVLGAADMPIDPPRDWEPKALRAKLEA
GADFVQTQFCMDVAVARRYARRLLDHGIAQRLPILIGVAPIPSAHSARWMREKLYGTLIT
DAQVARLEKARDPKAEGNRICIEVLQQLAEIPGVAGAHVMAPQNFTEIPVVIAESGVTGK
KRKT
>A0A521V8Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MLTSLDGGTRTAALEIAAYAAELLACGSIEMGAHQPEMARRIAALLPSGTPVFVNHLPRH
SLADALASLIAVREAGLEPVPHLAARRIASRGELEAFLNRAAGAAGVRKVLLIGGDEMAP
LGPYADGAAALRSGVLSACGIREIGIAGYPEGHPRIPAAALESSFAEKLALAAGEGLGAF
VVTQFSFAPARVIEYCAGLARRAPGVPVYVGLAGPSSAAALLRFAQRCGVSASLRALRAQ
GFGAVQLVTHTDPGDQLTTIARYCMAHVDCNVVGAHVFSFGAAVASAEWINRFIARST
>G6F474|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus delbrueckii subsp. bulgaricus CNCM I-1519|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADYLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILNRYQNSKEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHRS
>A0A7W7VCB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola algeriensis|TrEMBL
MTSVVARIPGDRPVFSVEFMPPRDDADELRLWNAIRSLEGLDPAFVSVTYGAGGSSRDRT
IRTTGRVVTETTLVSMAHLTAVDHSVAELRNVIGWYASLGIRNVLALRGDPPGDPNGEWV
KHPEGLEYAEELVSLVRSLGDFCVGVSAFPYGHPRSADLDEDTRYLVSKLRAGADFAIAQ
LFFEADDFLRLRDRVAAAGCETLLLPGVMPLTTPRILSKTVELSGADVPASLAGRLDPLA
GDAKAFREEGMNVTTELCERLLAEGVPSLHFYTFNRSKATKEIVVDRLGLAPGRSQLRSV
G
>A0A3R5WQ50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus eutactus|TrEMBL
MNILESLKDKLLVADGAFGTCYAGMYGERGTVAPELANMRHPERVLEIHKEYVKAGAVII
RTNTFAANTASLDADMDYVISNVRAAVKLAKQAVAEAGEPGIDRKKAYVAGDIGPIPVDA
GLTLNERVSQYKLLGEAMQDMGVDIIWFETFPEFNVLEPVVKQLKARKDTPVMVSFCVNQ
FGYSNCGFSARALLSQAAVNSDVDCVGLNCGVGPYHMLQLLKKLDIDCGKPVSIMPNAGY
PKFTQSRLVFNDNKEGFIDKIQDIAALGADIIGGCCGTNPEYIRQIKESVKKGDIVKAAK
VHVEKQQFDNAPKDNFLKGRLKSGKAAVKNAGGHKLIAVELAPPVDVNDQKLLDAAHILK
QSHVDVVTFPDSPSGRTRADSILMAEKVHKETGLRVMPHLCCRDKNAIAIRGSVLGAQLN
GIKDFLVITGDPVPVMFRQTTRSVFNFDSVGMMKLLQTMNEEVFIGDKITYGGAINQNRI
NTKFEIDRIKRKLEAGAEFFLSQPVFSREQAQILRDMKAETGATILVGVMPLVSRRNALF
MKNEMSGIEIPDEIIERYGENATRQEGEDCGIQIAREILDYTADFADGYYFSFPFNRVHM
LAHIVD
>A0A674P2Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Takifugu rubripes|TrEMBL
MVNQVQSVDSSWQSSKADSSGASNSSGESSKESSRCSTPVLDADRSDRLRDKMRRRIESG
DHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKDKITGYLGKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAV
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYQQDLRHLKEKVDAGADFVITQLFFRAETF
LKFLDDCRTIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITSILEPIKDNDAAIRN
YGIQLAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWTEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELLSEESVFEVFTFYITAQSNRCGQKVLCLPWNDEPLAQETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGRNLTNAPDMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWA
KLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDSPYRTSGSVP
>A0A0Q5EJB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Leaf127|TrEMBL
MNLLKQALHEQRFICLVEFVPKPTAKSFAAFEALMQRRTLCGWPLVATIADRVASRFDLS
PLDAFDRLADPAPALLHFSGKDRERHDLLQQLEHMDRLGLEQLFIISGDRLPGHEPGQQP
VRYLESVPALQQVRQARPDWLLGAALNPFKYREEEGGAQYFKARKKLAAGADFLTLQLGF
DAHKHLEALTWMRQQPSPRPLLACLMALTHGRATMLEHVAGTVVSPSMRAAVAAEAEVSK
AHAQQRSISRLGLQVIGLKLMGYAGVELSGIHDLTQLQALEQAIEHWQAQITTPAQWSEA
WQASWQTPGQPPVTFHPPGATWQWGQSTVSASLQEKTRYHLLAGLHHQAFSRTTWLSRAL
GWGVRRSLWSTPGGASALHRIERSLKRPMVGCDTCGQCRLEDTLYICPETCPKGLANGPC
GGTTLNRCEFGDRECIHSIKYRTAKAVGQTAVLTERLIPCIEADHRHRSSWPGWFDAAED
LPSNPRSRFSGECSVQTDPDQ
>A0A833VTF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frieseomelitta varia|TrEMBL
MEHTPAPYAPRSVYGYALYIGSNMLFVLFLIWAVIPDQILYTLGLTYWPSKYWAVAIPIW
ALTALATFAFIIYPAVNLSMTPDINDIATITDKHSCSKKETIPGGISPVYDIPITEVCRK
LYLTKKKHKIRDQGIDNECDNNTNYFLFTNIKCQMIDLRKTLKDIINTNAISCSFEIMRV
KNNDFYQRFFAEVNKYHPSFYTLTWHIKNDMKDYLSLDVFNALPNNTLLHLIANNLTPTD
VKIILKKALERDIRNIFVLRGDSTKSNGEFPHAVDLVRFIRNQFDDIFCICVAGYPEMHP
ESSSKEMDLIYLKEKIDAGADFIITQIVFEANIFIKFVNDCKKIGINVPIIPGIFPILNY
MCLQKMAKICNIKVPKIILNTLECIKDNNEKVHNYAVEIATNIIKEIIASKTTCGFHFFT
LNKPSLSLEICDKLGIFC
>A0A833HIR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobaculia bacterium|TrEMBL
MKVTEHLERAAAPPISFEIIPPLRGGNIHSLLALIEDLAKFRPPYIDITSHAAEVVYEET
PQGLQRRVKRKRPGTMGVCALIQNKWDIDAVPHVLCQGFTREETEDFLIELRYLGIDNVL
AVRGDESGYQKPLRDGKTANDFAIDLVRQVADMNRGRYLATDLLDASPTDFCVGVGGYPE
KHFEAPNLETDIRRTREKIEAGAGYVVTQMFFDNARYFSYVERCRAAGITVPIIPGVKIL
TARAQLASIPRNFYVDIPSALSDEASAVPEAQVAEVGVEWAERQVRGLLDGGAPSVHFYV
MQNARAVSRLLDRLRLA
>A0A0B4GWH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium guizhouense (strain ARSEF 977)|TrEMBL
MDKITDKIAALPADREYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSKRLVDKALEDAKALGIRNILALRGDPPRKEE
YCDAEDSEDDGQQDFTWAIDLVKYIRRKHGDYFCIGVAAYPEGHSDESHPQDQSLEHDLP
YLVDKVQAGADFIMTQLFFDISAYDHFEKTLREHPSGAFKTIPILPGLMPIQSYQMIKRT
TKLSHAKMPPAIMDRLDAVRGDDEKIKLVGVDIVSELIDQIRKIKSRTPGRRGFHFYTLN
LEKAVSFIVERTGLIPRESENEEALIDDGTLAPPAIQVNGTRASTHSRTSRRHSSVGSDP
YNRVIVAGQPPSHPEWEATGQEAGVPAESINSRANTLAISEGEGVLGREATWDDFPNGRF
GDSRSPAYGEIDGYGVSLHMSVNQAVTLWGCPTSRQDVNNVFVRHIKGEISAIPWSEEGL
SPESSTIQSRLVEMNGKGWLTVASQPAVNGISSSDRTFGWGPVNGFVFQKAFAEFFLPSA
DWHTLAEKLKGSDYFDSVCFYAANAKGDFVSSDTSGGRSTRTVAASTNAVTWGVFPGKEI
VTPTIIEEVSFKAWSEEAFGLWGEWAKVYGRGSESEKVLSGIRSDYWLVNIIHHDFIDRE
ALWKLLLE
>R6KML2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides cellulosilyticus CAG:158|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYDTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELAYEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A0Q5IRT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. Leaf334|TrEMBL
MSAAAVQPRTPGTHASPSRRAVAANDRPTISFELFPPRNPDAAPRLWATIQQLETVKPDF
VSVTYGASGKTRVTTRALVRRLLRETSLNPIAHLTCVGTSREEITTIVGEFLDEGLRSFL
ALRGDPPTDQSDWEAHPDGLQTAGELVELLREIEAQRCADSPSQAVRARVRPLSVAVAAF
PRGNHATGGTRAQDVASLLAKQEAGADFAITQVFYDAEDYLGIVAEAREAGVTIPIIPGI
IPTTDPARLLRMQELTGVPVPQDLLDLLGSADDELDRHRRGIRASVDLVNGVLDGGAPGV
HLYTYNQHHAALDLLEGAHLDGGARTAPDLASWPQDSAPARSTRD
>A0A1J5GJF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillatoriales cyanobacterium CG2_30_44_21|TrEMBL
MPSDQTFNQFRQAIARKEFLITAEVSPPKGSDPSHMLEQTQLLKGRVHAINITDSSRAVM
SMSPVAASVLIQQRLGIETICQLACRDRNRIALQGDLFGAAALGINNILALTGDPVKAGD
SPKARSVFDYESVRLLQLIQKLNQGLDANDKALPNQGTTLLAGAAIDPQSPSWSGLEKRF
ERKLLAGAQFFQSQLITDFDRLDKFMQQIASQSDKPVLAGVFLIKSAKNAQFLNKFVPGV
QIPDRLIERLAKAKSPLQEGMAIAAEQIQIARQICQGVHIMAIKAEHLIPEILDLAAIN
>A0A806E6Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus casei (strain BD-II)|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A496PYW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MGSNDMDLLTALASGPILADGAMGSYIFEQTGRLSEANHVYEALNIDSPDLIRQIHFAYL
SAGARCLTTNTFAANRTRLAPVGEGVRLAEINRAGVRLAREAISSFQRQTDAQSPCFVLG
SIGPTHETNESQQQAKQVYAEQLGALLEAGVDAIVLETFTFLPHLRAVLELIGEGVNSPP
VFAQMSLQQRGEEATWDPDPVAFVETAADLGAAVVGVNCCAPWEASAFVDAVEQVPAVRQ
RHIHLSAMPNAGGIQRIGHRYMTRVNPEYMGKLSRTLADRGVRLIGGCCEVHPRHVREMR
NFLTSRRAGGKTAAIVATNGHAPVGDEVKKDNGPFSRKIKEGTFAVSVEVVPARGTGPHV
LARKVEFVRHLAASGLVDALDVTDGSRGIPLMPPGDFINVLREGLGWTTSTGDGVEFIAH
FTSRDLNVLGLQSRLIGYWGNRIHNMLFVTGDPPKMSPTYPRSTAVFDLDSVDMIHRAQG
FMNRGLDFGGQPLGKHADPRTHFTIGSGFEPEAVDGAHELDKLRHKIDRGADYIMTQPVF
RYESFNRLEPFRDQVAILVGVMILTGLEHARRVAEIPGVSIPADFLDRLGAYPDPADQAK
VAKDIALEQARWVKRQGWAGLYLMSPGSMQLTLDVLQAGD
>A0A7K4QEN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neopipo cinnamomea|TrEMBL
MVNETQQSCSASSSSKSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELSVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGHRVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIITALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>R4KFU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoscipio gibsoniae DSM 7213|TrEMBL
MKNLSKLQQILDNGQFAVTAEIGPPKHSSAEGIRHHAEMMRDYVDATNITDNQTAIVRLS
SIAAGVHVLANGIEPIVQMTCRDRNRIAMQSDLMGAYSLGMRNVLCLSGDHQKFGNHPTA
KNVYDIDSMQLIYYLRRMRDEKLFFSGEEIKEHEPQFFIGAVANPFADPFEFRVDRLEKK
VEAGAQFIQTQCIFDMERFERFMEMVRERGIDERVHILAGVTPMKSWRAAKYIQNNVSGM
IVPDELVERLKNAEDPKREGVDICIEQIKYIKEKVKGVHGVHVMAIAWEEVVPEIVEKSG
LYPRPKVG
>A0A7K2MIA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID6013|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPTADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCRTPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A6N6PXM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
CSVTYGAGGTTREKTLGIVDRIQRDHDLTCMMHLTCVGATQAQIAQVVAEARALGVHNIL
ALRGDPPPGSAEFVRTEGGFEFSRELVQFLRQSAGLCIGTAGFPEGHVAQKAGKLVDWGF
LADKIRAGADFVVTQLFFDNDDYYRFRDHLVSRLHIDVPLVPGLLPVIARAQTKKFVELC
GARLPAPFLAKLEALGDDDAAVTAYGIDYCSKQVEDLLANGAPGAHFYTLNKAHSTASVL
KNLGH
>A0A7C5R028|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MNTAPTLREAFDSGQFCYGAELVTTRGFASPAEPARFVELGQALTSDPRITWVSITDSPG
GNVMLPPDTLARALAGRGAHIIVHLTCKDRNRNALEAAAWRLASDGFTNVLAMTGDYPRS
GYGGLASPVFDLDSVSLIALLKAMNDGLAVPGRKGETVTLPKTDFFIGACVSPFKRHENE
LMPQYFKLLRKIACGARFIITQLGYDMRKFYEVKLLLAAHNIQIPLIGNVYLLNRTVAEM
FHQNKIAGCVVSAKLLELANKYAAGPDKGRAFFLDLAAKQLAVFKGLGFTGGYLGGIAKA
ETFFEIIERSQQFGETDWKTFAREIQFPQPDEFYLFEQDPQTGLGDPNRLNPRLAMRPEA
VDFSYRISRWVHDKFFTPNTPGYRFMQRIYRRLDQRPGPLANAAHGIEKLSKFVWFGCKD
CGDCSLPDVGYLCPMVSCSKNARNGPCGGSADGQCEMLDKPCIWARAYDRLKHYDEARDM
LKGPAIFYNAQLKGTSSWANTYLGRDHHAQQPNDHKEK
>A0A8I1SVD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHVQDIFSVRRPTLSLEVFPPRTPESTDRLFETIVQLEDVAPDFVSITYGAGGSTRELTH
DLVVRLGTETAFNLIPHLTCVGHSRWEVERILERYAHAGVSNLLALRGDLPGGGCGTVGD
FRHAADLVRAIRRFRGHSDPRGFGVGVAGFPEGHPGTPNRLLEMDYLKAKVDAGADYICT
QLFFENRDFFDFRARCDLAGIHVPIVAGIMPVTSASGLNRMAELAGGARFPARLLRDLRR
ANGDPDVVRRIGIHYATEQCVDLLHHGVAGIHFYTLNQSAATREILSNLGSLRQAGDAVR
EKPGAG
>A0A6N6M6B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salibacter halophilus|TrEMBL
MKVTEHIEKANGKALFSFEILPPLKGQNIEGIYSTIDPLMEFKPPFVDVTYHREEYVYKT
HKNGLLEKTVTRKRPGTVGICAAIMHKYKIDAVPHIICGGFTKQDTEDALIDLDFLGIDN
VLVLRGDPIKSEKRFTPEPNGHAYAIDLMEQVKNLNDGVYLDEDLKYNSPTNFCIGVAGY
PEKHFEAPNMKNDLYWLKKKVENGAEYIVTQMFFDNSKFFEFERQCREEGIDVPIIPGLK
PLSTERQLSLLPQIFHLDLPDALVDEVNKAKSKDAIREIGVEWCIEQSKELIKNGSPVLH
YYSMGKSKNIQKIAREVF
>A0A2V6AZW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
IHIPIIAGIMPITSISGLKRMAELAGGARFPAKLLRALQRCQSDPEMVRRVGIHYALDQC
HDLLNNDVAGIHFYTLNRSDATRVIFDSLGIPRHRGAEASSV
>A0A2V5PVJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMQGGSPTFSFEFFPPQTPEAAETLYQTIRELEAYMPHFVSVTYGAGGSTRDLTH
NLVERIKTTTKLDPIPHLTCVCHKHEEIEAILNRYAQNAIGNILALGGDPPRGCAYDKSA
DVFQHAVDLVKFIKKFNESGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALAGIHVPILAGIMPITSLSGFKRIAELAGGARFPAKLL
RALQRCENDRAMVSRVGVHFALEQCHDLLDNDVAGIHFYTLNRSDATRTIFDSLGIPRQR
NQEAPLA
>A0A386TZB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium paragordonae|TrEMBL
MSETAVAPDAGCPKRMEYGPCGGVRPDGQCEMRSGACTFTDIVPWNGPVRGMVRGPVPLV
LTDFSCAPFDRDDVAATAAVLASSCDAVLVGEHQNKPDFPPTLMGSLLLDAGVAPWITLS
CRDRNRIVLEQELRGLRTIGVDTVLCVTGDGRGYDVRPDVTQTFDLDGLRLVSLAASLGA
VPAVPETPTAPPVAARPARLVEKQRAGAALAVLNHVPFPDMIAEFMKSARAQGLSIPVIA
AVAVFTDSVSAAVLQGLPGLELDPAVTERVLSSADPIAAGISAAVSEAQSLLSIDGIEGV
NVSGLASASGTRVGAEIKAEVGRLIREGVA
>A0A2V6ECZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMQGDSPTFSFEFFPPKTPVAAEILYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQTTTKLDPIPHLTCVCHKEHEIESILIRYAKTCIGNILALGGDPPRGCSYDKSG
DAFQHAIDLVKFIRRFNESGGHPDRRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALAEIHIPIIAGIMPITSMSGFKRIAELAGGTRFPAKLL
RALQRCENDPEMVSRVGVQFALEQCHDLLDNNVAGIHFYTLNRSDATRIIFDTLGIPRRR
NAQAPTV
>N9G116|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii ATCC 9957 = CIP 70.31|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAADLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVEKVQAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNSSNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A2V6DFP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIADIMREDSPTFSFEFFPARTPDAAEILYHTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHDEEEIE
>A0A0F2DBB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>C3QXU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. 2_2_4|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A2P6JSL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MYb185|TrEMBL
MTKQINVPVSFEFFPTKTEAGHEKLIAAAHVLAEQQPEFFSVTYGAGGSTRDRTMNTVLQ
LDQQVKIPTAPHLSCVGDSKDDLRQLLNQYQESGIRRIVALRGDLPSGMGRASGELRYAN
ELVEFIREETGSHFTIEVAAYPEAHPQARNFEDDLKNFVRKANAGADSAITQYFFNADCY
FHFVDRVRKAGVELPIVPGIMPITNYSSLSRFSDACGAEIPRWIRKQLESYGDDTRSIAA
FGTEVISDMCQRLLAGGAPSLHFYTLNQAEPSLAILRNL
>A0A7W5U6E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK612|TrEMBL
MSSRSESHNAGIRISFEFFPPKSEEAEQQLWNTVEELSDWDPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLATGVRRFVALRGDPPGGVGSAYKP
HPGGYANAAELVGALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKAENGANRALTQF
FFDNDAFERYHDRVHAAGIKIPVVPGIMPIQNLTQLKRFASACGTTIPTWLDERFDGLDE
DVEERAKVAADVAAEQIQDLVRRGIHEFHIYTMNRSPLVSAVLERLGLQRKMASQAGAAA
>A0A5E4KD35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon|TrEMBL
MSFRDKLLSGDFIVTAEISPPKGTDKKPLLNEAARLKGVADAINITDNQRAIMRMSPSAA
CSILQDNGYETIMHITCRDRNRLSLQSELLGACGMGIRNILVMTGDHPSKGDHEGAKPVY
DLDSVQLLELVRKLNSGYDFSGNRLEGRTDFTAGAVSNTRLDYVSLIKLKKKIKSGASFF
QTQAIFEADSLSDFIDKIDEAGPKRPKVIVGIMPLRSEKNALFLNKNIAGIKVPDKIIKR
MREANDPASEGIEIAADLVRELKSLCDGVHIMPVKDHENTKKILEMAGIR
>A0A6G6WJ84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides anomalus|TrEMBL
MRNKSKVNAAATVARLLEHARYEVLPTASIEDTVLEHVPSTSAVTVTASPSKGLEATLDL
TERLTKHGYTAVPHLAARMVRDRAELEEIAARLTSQGIESVFVPGGDADPPGAYPDALSL
LEELKVIGTPFTHVGITGYPESHPTISDDLTIQSMWDKRKYATHVVSNLTFDPDLLTDWV
ARMRGRGITLPLLLGIPGPVDRTKLLGMATKIGVGESTRFLMKNKGTFARLAAPGGYTGE
RFLEKVAPALSGPEMLVEGLHVFTFNQVAATIAWRDQLLDELSARA
>A0A3A6JY13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. AF10-46|TrEMBL
MKDVREILKKRPLLFDGGMGTYYKAKPGQECEQANLLDPDGILTVHRAYLEAGADAIKTN
TFGLPRMAAAQNPMWEAMADEGWKLAAQAAAKTSAAVFADLGPAPDTEALPAAQIYTALA
ERFAALGAKNFLFETLSSDAGVAEAAKKIKETVPDAFVLVSFAVLPDGYTREGRHCAELV
RSMTACGAVDAVGLNCVSAPGAMRTLVQQLGETKLPLAVMPNAGYPVVTRTRVQYQGRPE
YFARELARLAAEGVRILGGCCGTTPAHIAALRAALDALPGQLPVAAAAPVPTAAKPEVET
DDAFLRKLNAGKKVIAIELDSPKDADLTGYLDGARRLQATGADLLTIADCPIARARMDSS
LVACRVHRELGLNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPLTVFGALNLNARNFDVELRRAQEKLQNGMSGFL
TQPVLSAQAVVNLKKTRETLGEKAKILAGIMPVVSQRNAIFMENEVNGIHVDAEIIERFA
GLDRAQGEELGLEVSVKAAQAAAPYADGFYLMTPFNRIALMERLIARLKDEGIAD
>A0A6P4IES9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila kikkawai|TrEMBL
MAHFVDSPRQNFFSYVPCVTFASKQHGVKEPRIGPLIEGRQLQQRLYYGIEVMPHTDGIP
VCLNLNRLLPFMPLFVSIAWLAKSSWDVEPLGRVDSLQLAKHLASKIPVMPHLTLYRLND
ERLDQFLDLNFSNVLALRGSTIYENQTYAYSKTIVERAKEKFKDKATVCVAGFPEGYNIA
EGEPPDLKIHLHYLKEKVDAGADCIITQACYRPEIIIDYVKKVRAAGITVPIMVGIAAHE
SFKKYKTIEKEQGARLPPRLHEKLAKMGNKFEKDVRTDPHLIRNLFVRINVNIICQILKA
DIQVYGFQIFTLNNFGATAGLLRELRQQKLFGEHSLFGFS
>A0A6L2R426|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfovibrio kirbyi|TrEMBL
MPDFYDTVESLCVLAPLFVSVTSGAIGSRQRNTLTATSEMARRGLNAMAHLTCVGAEPAA
IAVFLKELRNGGVANVLALRGDAPRDRSWTPESGVFQHASDLVAFVRERDPDMGIGVAAY
PAPHPESSSFSADRDHTAQKLLAGADFAVTQLFFDIREYGDLVDGLRARGIDAPVVPGIL
PILSFDSLKRILSLCGANIPGKLYLQLEEADKKGGLEAVREAGHNFAVRQIRRLLDCGAP
GIHLYTLNRSDLCLHIARDASLSGMRAEL
>A0A256HTI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halorubrum sp. Eb13|TrEMBL
MSAGTQAIKRSDGVGALLTDARFELMPFESFEDEIRHLPDDATIAVTTSPQLGIDTTVER
TEQAAALGYDVSPHIAARYVEDRDHLDEIAERLTDAGVTDIFVPGGDREEPAGEFESAHD
LLVALDELGHSFDEVGITGYPEGHDFLDAEALSDAMAKKSPYATYLVTQLCYDPDAVLEW
IDDIRDDGVDLPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVRQLVGSRG
VYKPDDLIDGLAPYADDDHYKIRGIHIYTFNQTPDTESWRTERLGR
>A0A2D8TXV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. EAC657|TrEMBL
MSSALQRSLEAGSVTVTAEVMPPRGGDPSHALAMAERMRGWVQAINVTDGSRAVMRMNSV
AVCRLLLDAGLEPVLQMAGRDRNRIALQADLLGAHALGIRNLLCLTGDPVQAGDQPHARP
VHELESIRLLKQVSAFNRGEDPVKNNLPDGPTDLFAGAAADPHCPSWSGLTRRLERKREA
GARFLQTQMVMDPRVLERFCRELATPMELPVLAGVFLLKSAKNAAFINRMVPGACIPDDL
IARLAAADDPASEGIAIAAEQVHRYLGIAQGVHVMAVRAEERIPEVLKKAGLSSQPL
>C6SF34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis alpha153|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRPLKPYQTVS
DGI
>M6FEU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira kirschneri serovar Bulgarica str. Nikolaevo|TrEMBL
MKKVSEIYGSTKGPVYSFEFFPPKTPEGDLKLMETVKELSLLNPDFITVTYGAGGSTRDK
TAQILSRISKNYSFPTVSHFTCVGSDKGQILETLKGIRSSGIVNLMALRGDPPKGEGEFK
KVENGFENATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVRNLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>R6JJ34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides ovatus CAG:22|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>D7DKY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera versatilis (strain 301)|TrEMBL
MKKTAFSFEFFPPKTADGIEKLRENRAKLAQYNPEFFSVTFGAGGSTRDRTMDTVLEIHQ
EGFQAAPHISCVSASKEEIRELLKTYQERGIKRLVALRGDVPSGEVSAGDFKYAVELVEF
IRAETGNQFHIEVAAYPEFHPEARTPKADLLNLKRKVDAGANSAITQYFYNADAYFRFVD
QCQTAGVNVPIVPGIMPIYNITQLARFSSVCGADIPRWLKMRLEEYGEDIDSLRAFGVDV
VSELCETLQAWGVPSLHFYTLNRSTMICKIIENISEK
>A0A562XI29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter hyointestinalis|TrEMBL
MLKDKIKENKPGILLYGITPPKINLSKDEAYQIAKKQLERLENTGIDGLVIYDLQDESSR
NNKKRTFEFCGTIKPEIYHKEFLKLSYPAVIYKAVGNYTKEEFANFLNTYNNDMLSVFVG
ASSKNDLLKFNLNEAYQLKKEQGRNVTVGGICIPERHEKKGDEDLRVASKIVKGCEFFIT
QAVYNIENAKRFLDDYANLGIKKVPIIFTFTPCGSPKTLEFMRWLGISVSKQFEDRLFES
DDPLSASVELSLDMFEFLYKYGRAKGVSVGANVESISTRKVEIEASINLLCGIKNIIQNE
KECNLEELIQSASKFYE
>A0A8C5CHW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gadus morhua|TrEMBL
MVNQVQRVDGSWQTSKSDSSGASNSGESSKESSRCSTPLLDADRSDRLREKMRKRMESGD
PWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSNKETSSMMIASTAV
NYCGLESVLHLTCSNQSQETITGYLTKAKQLGLKNIMALRGDPLGTDWEDEEEGFNYATD
LVKHIRSEFDDYFDICVAGYPTGHPEAQSYAEDLQHLKEKVDAGADFIITQLFFRADTFL
KFLRDCRAIGITVPILPGVFPIQGYQSLRQLVKLSKLEVPEEIMEVIEPIKDNDAAIRSY
GIHQAVEMCRVLLDSGAVPGLHFYTLNREVATTEVLRQLGLWIEDPRRPLPWATSANPKR
KVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LKMWGEELTSETSVFEVFTSYITAQVNRGGHKVMCLPWNDDALATETNLLKDELEKVNRR
GVLTINSQPNINGKPSSDPIAGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVQGHNMTNAQDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQVLDDMFELGCTTILTDRFLFCVS
FFFFF
>A0A8C4YWP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gadus morhua|TrEMBL
MVNQVQRVDGSWQTSKSDSSGASNSGESSKESSRCSTPLLDADRSDRLREKMRKRMESGD
PWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSNKETSSMMIASTAV
NYCGLESVLHLTCSNQSQETITGYLTKAKQLGLKNIMALRGDPLGTDWEDEEEGFNYATD
LVKHIRSEFDDYFDICVAGYPTGHPEAQSYAEDLQHLKEKVDAGADFIITQLFFRADTFL
KFLRDCRAIGITVPILPGVFPIQGYQSLRQLVKLSKLEVPEEIMEVIEPIKDNDAAIRSY
GIHQAVEMCRVLLDSGAVPGLHFYTLNREVATTEVLRQLGLWIEDPRRPLPWATSANPKR
KVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LKMWGEELTSETSVFEVFTSYITAQVNRGGHKVMCLPWNDDALATETNLLKDELEKVNRR
GVLTINSQPNINGKPSSDPIAGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVQGHNMTNAQDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQVLDDMFELLDAA
>A0A353X688|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MRFSFELFPPKTPQATAALEAALPRLAVLNPALFTVTYGAGGTTKDGTLATAATVAARTG
VPVAAHLTYLTTPREALLAYAQDLWGRGVRHILALRGDLPPGRTFADFAGPQYFRSTAQF
IAALRDVHDFEISVAAYPEVHPDAADAAEDIETLKAKVAAGAERAVTQFFFDNADYWALV
DRARAAGVAVPIVPGLLPVHDFPAMARFAAKCRARVPADLEARLAAEGPAAVLAAQIRDL
RAQGAAHAHIYTLNRADIVEQALAKI
>A0A2E4F1H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTGLPEHDKIGSHRPMVSFEFFPPKTEKMAKELWVAVRRLAPLKPRFVSVTYGAGGTTRD
RTHSIVSQLRKETSLQPAAHLTCVDSSIEEVNSVVRNYYEAGIRHIVALRGDPTNRESQF
VPHPAGYKGAVELVSGLKKIANFEISVGAYPEPHPDSRGTRSDLDYLKRKLDAGATRFIT
QFFFDNDFFFRFIDSVRGAGINAPIVPGILPVTNFQQVARFSTMCGASIPQWFKYRFDGL
DDDPGTRQLVAAHTAADQCFELXESGVTELHFYTLNRADLVFAICHMLGVRAVQNSXPVS
T
>A0A2E9YKZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MVNLSFEFSPPKTEESEKKLWSSIKHLAPLNPKFVSVTYGSGGSTRNRTHKCVEKIINET
NLKPAAHLTCVSSSKMEVDQVIANYHEIGVRHIVALRGDMPNMGTFEPHPEGYSDSVELV
KTLHNFGVSEITVATYPEKHPESKSIDDDIEFLKRKINAGANRAITQFVFDAEILLRFRD
KTEAAGINIPIIPGIMPTTNFKNVKNMAQKCGATIPNWLEKKYEGLDDNHKARREVAKEV
GLDFCEKLISNDYINLHFYTLNQADLTYDICNSLY
>F4JAK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabidopsis thaliana|TrEMBL
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGSTA
DLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEADGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMNL
GLIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPHGRWGDSHSA
AYSTLSDYQFARPKGRDKKLQQEWVVPLKSIEDVQERIGYQTPVSPM
>A0A3D2SYB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MWADRTAGLARRICEETGIETAAHMTCIGQTKDALFEQLDMYAAQGIKHIVALRGDIPRD
KEKPAPDNTDYFHYANEFVEGIKAHNSDFDISVGAYPETHRDAVCAAEDLRFLKQKIDAG
ARRAVTQFFFETDVFAQFLEQARAAGIDCEIVAGLSAINDFERICRYAKGAKAHMPDALI
KQFADQQEDHLSLAAVFLENQIKSLMQGGTRHFHFYTLNTAEPLLTALERL
>A0A562UTL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altererythrobacter ishigakiensis|TrEMBL
MSPTLDQMHEARTALDSPLFKGLPGDIDVSFEFFPPKTEKMGETLWKSVETLKPLGPRFA
SVTYGAGGSTRERTHEQVVRIQTEAGIPAAAHLTCVAATKEEVNEVARHYWESGIRHIVA
LRGDAPDGGGQYTPHPGGYANAVELIAGLKEVADFEISVAAYPEVHPDSPDAQSDLDNLK
AKFDAGATRAITQFFFNTKCFFEFRDKAAAAGIKGEIVPGIMPVVSFAAVQRMSGLCGTD
IPHWMEGLFEGLDDRPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GMRPKAGL
>A0A242NRY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apis|TrEMBL
MKTNLLFNQKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMLKILHDLKCAGIDNLLALRGDISPNVPPKDDF
RFASELVTFIKENGDFNVIGACYPEGHLEATTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKAHDMDINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKSA
>A0A8C2C769|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MDNTERSDVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDH
WFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVN
YCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDL
VKHIRCECDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGAHFIVTQLFFRAETFLK
FVKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYG
IQQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRK
VEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALL
QMWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNCRG
VLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNY
HIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKL
YEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQEEGRSIQA
F
>A0A8C1RJ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADAGWQSSKSDSSGVSNSGESSKESSRXYGCVPGGSQNESFLFLCVRFDRMGSGG
PLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKR
LGLKNIMALRGDPIGEDWVEEDGGFNYATDLVKHIRCECDDYFDICVAGYPTGHPEAESY
DEDLRHLKEKVDAGAHFIVTQLFFRAETFLKFVKDCRAIGITCPILPGIFPIQGYHSLRQ
LVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGIQQAVEMCKVLLASGEVPGLHFYTLNREV
ATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNG
RWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITGQTNPSG
HKVMCLPWNDDPLAPETNLLKDELEKVNCRGVLTINSQPNINGKPSSDPIVGWGPAGGYV
FQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVQGKNITNAHEMQPNAVTWGIFPGR
EIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFP
LDSCLWQVIEDMFTLLDSPPETQEEGRSIQAF
>A0A8C1UI61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MDNTERSDVGWQSSKSDSSGVSNSGESSKESSRCSTPVQDADRTDRLRDKMKRRIESGDH
WFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVN
YCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDL
VKHIRCECDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGAHFIVTQLFFRAETFLK
FVKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYG
IQQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRK
VEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALL
QMWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNCRG
VLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNY
HIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKL
YEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQEEGSPS
>A0A7X7FB93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MNRDFLQRIAAAPLVFDGAMGTVIYQKGVFLNACYDELCLSRSSLVAEIHRDYVAAGADV
IETNTFGANRVKLAEFGLAEKLPEINAAAVTLARREAGAAVLVAGACGPCSARGAGLAAL
DAATIEAAFDEQVGLLAQAGADLVVLETFHDADELLLAARAARRHGLPVVASVSPAAFEK
TPLETVLARLDASPDVDVVGLNCQYGPAEMLEPARRARAAVRKPLLVMPNAGGPHEVGGR
SLYLTSPEYYTEYAKKYIELGANGVGGCCGTTPAHIRMAAKALHVLSGVKRHLEIRAADE
APANAGADPAPFASKSPFAARLAAGRRITSVEILPPRSAQGLEGFLAKCRACEAAGVDAV
NLPDGPRASARMSVVATAFAMRAAGLAIEPIPHCCCRDRNLIGLQSDILGGVALGLKTWL
FVTGDPPKLGNYPDATGVFDVDAVGLVRLCANLNRGLDAASQPLDGPVPLAIGVGLNPAA
IDLDREIAHFEAKVAAGAEYAITQPVFDAEALLRFLDRLAKRPPLIPVVIGLYPLLSAKN
ADFMNLYVPGVHVPEPILERLRQCKAKEDAIATGVEIAREIRARLADAPIAGFQVSAPLG
RTDIALNVLRE
>A0A7J5AIN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum aiptasiae|TrEMBL
MKVTEHIKNANGKTLFSFEILPPLKGQHIQSIFNNIDPLMEFNPPFIDVTYHREEYIYKE
LENGLLKKQVVKKRPGTVGICAAIQNKYQVDAVPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPEKDGHKYASELVSQIQSLNNGKYLDDELQNSSQTNFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKNGATYIVTQMFFDNQKYFDFVAKCRAEGITAPIIPGLK
PISTKKQLNLIPHRFKVDLPDDLIMNVVKCKDNSEVRQVGIEWCIHQSKELIKAGVPLLH
YYSMGKSTNIQQIAKEVF
>A0A7H9HW30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Torulaspora sp. CBS 2947|TrEMBL
MSVRELYDGKSRPALSLEFFPPKTETGKRNLLERMVRMSALDPLFITVTWGAGGSTAEKT
LELAAIAQRSLNVPVCMHLTCTNTDKTVIDEALRTCQQVGIRNILALRGDACIEDCVDQE
SATQDAVEFKHAVDLVKYIREQYGSYFCIGVAAYPEGHCEGEAEASEQDPLRDLPYLKQK
IDAGADFVITQLFYDVGKFLKFHKLFVDHVSAEIPLIPGLMPINSFLLFNRAAKLSHASI
PQYILDKIPPEVQPDDNAVKSICVDVLADIIDTIYRETNGRVKCFHFYTLNLEKAVAHIV
AKSHVLHHIMKEAEEEEEEEAKTRADEDGDIALDDGPGTATLQEDNRKRRRNSSNVSTDF
ISNQLAVHKTRRSNMGIPSRKVAISISQGTGTLGRDATWDEFPNGRFGDSRSPAYGEIDG
YGPSIKAGSKRALQLWGSPTNVEDLRNIFIKYLENSIDSLPWCDLGLSPESALIQEELIQ
LNDRGFFTLASQPATNGASSTDKILGWGPAHGVVYQKAFVEMFVQKERWNASLKHMVDHY
GREKLTYYVGGSDGSFATNLEPESSNVVTWGVFANSQVIQTTIISEESFKAWRDEAFSIW
LEWAKLFPRNSQSNSFLRQMHQGYYLVSIVHHDYNQSDELWEILLS
>A0A6I6PWU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rossellomorea marisflavi|TrEMBL
MNTLLDALSENILIADGAVGTLLYSYGVDRCFEELNLSHPEEIINVHKQYIEAGADIIQT
NTYGANYAKLSRYGLQDQVKEINEAAVKLAKKAAKEGTYILGTIGGIRAINQHISLEEVK
RGFREQLYCLLLEGVDGILLETYYDFEELRTVLQIVKKETDLPVIAQVSMHETGVLQNGM
DIKDALGELELLGADIVGINCRMGPFHMVKSLEGVPLPKSSFLSVYPNASLPNYEEGRFY
YAAEPDYFGDISNELRLQGARIIGGCCGTTPAHIKAVKERMISRVPVKEKKVKRQELIKL
KDPLLQKSLLHHKVKVKKTLIVELDPPKHLDTGLFFQGAKALKEEGIDAITLADNPLASP
RVSNDAMGTLVQQKYDLDPLVHITCRDRNLIGLQSHLMGLHTLGIHNILAITGDPAKIGD
FPGAASVYDLSSIELIELIKQNNEGLSFSGKSLRQRTNFSVGAAFNPNFRHLDASVKRLE
KKQSAGADYFISQPVFSCEHLVQIAEATRHLQSPLFIGIMPLISSRNAEFLHHEVPGIKV
PDQARRLMKEAEGDPLQSRAVGMGIAKELVETAMELFNGLYIITPFMRYDMSVELIRHAN
VIEKEKREVPYDHNIV
>A0A1F9C908|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_49_23|TrEMBL
MKKNRFKEALLEKKEFIYTLELVPGRGSRGKTQDDILRIAEKAAKSRLVHALSITDNPGG
HPALSPNVMGLEVARLGIDPIIHFTCKDKNRNQIESTLYSLDRIGISNLLVMSGDYPLYG
FEGKAKPVFDLDSIQLLHLIHQMNNGLDLDGKAPGGGVRVPPTHFFKGCTVSPFKKYEAE
AMPQYYKLFKKVEQGADFLITQVGFDARKFDELLRYMRHHGIRIPIFGNVYILNQAVAKV
MNRGTVPGCVVTDELCRVIEEEAKAPDKGKKARLTRAAKQIALLKGMGYDGVHIGGPNLS
YEEVEWVIGKSTEFFPNWEEWVHEFTFPQKDGFYLFEKGAKTGLSRDDWVRQRSKPRKVL
GHGIMRFFHRLAFTPEAPLYRPAQRLFKKIDGTTLEGPVTELEYWIKFISSRCRRCGDCT
LLEVAFLCPQSQCPKYLFNGQCGGSFEGWCEVFPGKKRCIYVRAYLRLKPYGEEESLKEG
YTPPRNWALDQISSWANYFLGRDHHG
>A0A8C2GZV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MQDYSWIHTCESSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCECDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGAHFIVTQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNCRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQEEGSQS
>A0A7X7G5F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MRHHITHKIYHIEILTPKQNSEQLEDDLAKFAVKYETVTKAGYVACITDNPMGIVSFQAT
DIIPELGLKVNPEQLMIHLNTFHTKKALDEILGTAQKMGCKYLLAISGDGSERLTRLTPD
ALGLTVNTVTSVELLRYIKHAYPGVFTCGVAFNPYEPQDLELEEMRRKVEAGAEFICTQP
VIGHNDRIGALKPFGLPVIIDAWMSKKLHLLSECVGYNIPEDTPYDPLSNLRELRRNYPD
CGLYLALLGFKTQFPVLKDIWV
>A0A099I303|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium innocuum|TrEMBL
MIENYLNTQGYMLFDGAFGTYYAQRYAEDQKPCEMANLNHPKRVAAIHQEYIEAGADAIK
TNTFSANEQHLECSWEMIRRILQEGYRIAKEAAKDKVKVFADIGPIMEQKNVSLAQQYQR
IVDVFLAEGADCFLFETLLNTQELHAVTSYIKEQCPQACIIVSFAVTADGYSRQGIAMSR
LLQDCLADEHVDACGLNCVCGPMHMKRLLDSIDRTQKPILIMPNAGYPTILANRTYFRDS
STYFAKEMREIWQKGARLLGGCCGTTPVYIQKTREALQEHKIIQKVQQPAQETQRIPQED
HNPLRRKLQRKQPVIAVEFDPPANCEIERFMNHVEFLKEAGVDAVTIADCPIARARVDSS
LIACKLHRELGLDVIPHMTCRDRNINATKALLFGLQIEGIRNVLVVTGDPIPSEDRQEVK
GVFNFNSQILAGYIRDLNATMFTSPFMVFGALNLNAVNFEAELAKAKRKVTQGMEGFLTQ
PVHSRQALFNLKRARKELQAYILGGVLPIVSHRNAVYMNNEISGIEVDEEIVAMYEGTTR
KEAQKLAVDISCKTMDEMRPYIDGYYLITPFNRVEIIADMITYIHKQ
>A0A5N6KI10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monilinia laxa|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALKPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRELVDRALEDAKALGIRNILALRGDPPRSEE
YRAVDEKNGNTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDKFEQSLRDHPSGAFKNLPIIPGMMPIQSYQMI
KRTTKLSHAKLPTNIITRLDEVRGDDEMVKKIGVDILSEMVEHLKGTKSQYLGPRGFHFY
TLNLEKAVSFILERTDLIPDADAVAALEPDLVPTIPDIADLLSVHSGSHKRSSRRRSSVG
SDPYNRIIITAPHTSNPSFEATANEAGVPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDPIFGWGPKNGFVFQKAFVELFL
PTSSWETLQAKLTSPALRDIVSFYASNSKGDFVSSDETIGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSATRKVIDGIKEDVWLVNVIHHAYVEGESLWDV
LLQ
>A0A1B7M2D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enteractinococcus helveticum|TrEMBL
MSQSTQSANVRQLMQDFSLEMTGKDVEALREAAPVIPAGTRINVTFLGNEDLDMRVTAAK
AVKELGFIPVPHISARRLRSEDELKEFLQALADVDAVKHVFAVGGDPAEPMGPYGSSLEM
LQSGIFAQYGVEDVSIAGYPEGHPDISDEVLARELKGKVNLLAEQNLSAVVLTQFGFDTD
PVATWLNELAAQNIAAPIRIGVPGPAGIKRLMNYAKRFGVASSAGIVKKYGFSLTNLMGS
AGPDKFLHNLADEVAVSNYQGTVGVHFYTFGGMAKTAEWARDFINKL
>A0A1V3RUL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. A25(2017)|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGASSAITQYFFNADSYFY
FVERIRQLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A2D8TTR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacteraceae bacterium|TrEMBL
MNFSLEVTTQSNLSDLPKLKDIYITFLPGTGYEDVVKQTAALSESGFNPIPHFPARSITN
LDMLKDYVEKVRAAGVKQVLIIGGDRDILGDYHCSLQLIETGLFDGLKIGIAGHPEGSPN
MTDEAIDEAMKSKTPFADYIVTQWSQDVDSLXKFVTDSPLPVHVGVAGPASVKTLVKFAS
FVGLKGSLNFAKKNASKIFDLXTVQTPDXVIQELRNKVDHFHIYAFGGIKKTNEWLQKEN
YYV
>A0A3A9UPM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. BL110|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTDVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
KGVDKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVRFAGFTDVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGLRSGN
>A0A166SIT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. HI0023|TrEMBL
MTTPRVSFEVFPPRSVDAAFKLWDTAQALAPLAPRFFSVTYGAGGSTRDLTQDSAHVLRR
TSGLPVAAHLTCVGASREETLDVARGFTEAGVTDIVALRGDPADGADRFTAHPQGFANSC
ELIEALADMNQFTIRVGAYPDSHPDAADEAANIEWLKRKFDAGADEAITQFFFEAETFLR
FRDACEKAGIDKPITPGIMPVVNWKSARSFAERCGALIPDWVHQSFDAAIRDDRHDLLAT
ALCTELCSELIDEGVDTLHFYTLNRAELTRNVCRALGVTPQVALSDVA
>A0A6B9YZJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. 14171R-50|TrEMBL
MKITEHIKNANGKTLFSFELIPPLKGQSIQGIYDAIDPLMEFKPPFIDVTSLREDYIYKE
HETGLLEKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLQFLGIDN
VLVLRGDARRGDASFVPTPNGHCYATDLLQQVVNMNNGVYLHEHYEGIMKTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKIDMGANFIVTQMFFDNQKYFDFVNNCRAVGINVPIIPGLK
PITTSKQLVNLSKTFHIDIPEALSDAIHDCKEEKHVKDIGIEWMIDQCKELVKFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A5M9HCS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcticibacter tournemirensis|TrEMBL
MKITEHIAGANGKALFSFELLPPVKGQSIQQIYNAIDPLMEFKPPFIDVTYHREDYIYKQ
HPTGLLEKVTYRKRPGTVAICAAIINRYKVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKADPAFMPTPGGHSYACELLQQVVNMNNGKYLHEDHDSNKTNFCIGVAAYP
EKHFESPNPETDFKYLKQKVDMGADFIVTQMFFDNQKYFSFVNRCRENGINVPIIPGLKP
ITTSKQLINLPKIFHIDIPLELSEAVSGCKTEKDVKDAGIEWMIHQCKELIEFGAPVLHF
YTMGNPEPTYRIAKEVF
>A0A224X5M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus reticulitermitis|TrEMBL
MKITDIYRAKNIQKKSVISLEIFPPKTDAGIETIYQTVAGLTHKPDYISVTYGAMGNVGQ
ENKTLEIAEKIKKAYGIETMHHLTSIHNNPEQITEILAEIKAKNVQNILALRGDLPKNTD
VTGCPDSYHYAHELITDIKKAGDFDIAAAIYPEGHVDSPLDVENIEHVKRKYDAGANFFI
SQLFFDNAKFLRLNDYIKNSGIEAPIAAGIMPVLQKSQVERMIFFGASLPTRLIKIINKY
KDSPEDLQKAGMDYACKQIDDLLARGVDGVHIYTMNKPFVANTMMDRYL
>A0A1M4VJD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenibacter palladensis|TrEMBL
MLKDRIINKESGFLFYGLTPPKINTEEDKVGIIADKQVKRLRGLKIDGLVLYDIQDESSR
TDSPRPFPFMPTLAPNYYSDKYLSDLKVPKIIYKSVGKYTADEFRSWIYQNSHNIDCSVF
VGSPSKNQVSGISLNEAYKINQHSNSSILLGGVAIPERHIKKGDEHIRLFDKVDKGCSFF
ISQCVYSVNNTKDFLSDYYYTSIETERDLVPIIFTLTPCGSLKTLQFMEWLGIDIPKWLN
NDLKHSNDILSKSIDLCKNIAIEILDYSVTKNLPIGFNIESVAIRKEEIEASIELLKDIK
GLMNR
>A0A6C0Y0K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter indicus|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
ERIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVLKFCERLIAGGAPSLHFYTMNNTEPTRQLVTDLGLA
>A0A4P5UYM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTSINLQEKLRRGTLLADGALGSELYARGIIHGSCLDALNLTDPAAVLGVHAGYLQAGAD
LIETNTFGANPFRLASHGHAEQVAAINQAGVVLARQAAAASGRAVAVAGSVGPLGVRLAP
FGRVKPEAAYAAFSAQIGALLAAGVDALVLETFSDLMELSEAVRAARDCAAAHPPVLLVA
SMTFTRDDRTQLGDSPAHVARTLAGLGVDVLGANCSIGPAQLLRVLKGMHAAAPQLPLSI
MPNAGMPELSGGRVVYPAGPDYFAQLTPDWLATGARIVGGCCGTTPAHIAALRQALDTPR
TASVRSVPARPSSPAESLPATDEPTKLATQLQSKRFVITVEMSPPKGYTPHKVLAGAHML
AEAGADVINVADSPLARMRMSPWAVCHLIQQQVGVETVLHFPTRGRNLLRVQGDLLAAHA
LGVRNVFVVMGDPANIGDFPQAFDTFDVAPTALLQLVKQRFNAGMDQAGQDIGQPTSFVA
ACALSLSAPDPAREIKLLRKKLECGADFALTQPVFDAQVARDFFARYAAEHGPLQLPVLV
GVLPLYSERHAGFLHNEVPGVHIPEAIQRRIAGAADAPAEGIRIALELLAELREITPIRG
AYLQPPFRRYELAAEIIEHLRAQD
>A0A8G1NVQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania psychrotolerans|TrEMBL
MREAQRALEAPLFSGLAGDIDVSFEFFPPKTDKMAQTLWHSVETLSPLSPRFVSVTYGAG
GSTRERTHEAVRRIVNETQMPAAAHLTCVNATREEVDAVAREYWEEGVRHIVALRGDPPE
GGSAYTPHPGGYANAAELIAGLKKVADFEISVAAYPEVHPDSPDRQADLDNLKRKFDAGA
TRAITQFFFDPECFFEFRDKAVAAGIEGEIVPGVMPVLSFSAVQRMSGLCGTGIPDWMEG
LFEGLDEKPEARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPEAR
Q
>A0A3B9J8Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPIFTPGRRWQPAFSPFKHESFAHQVLATAELAVKGPLFGCRMCGNCMLQETAFICPMEC
PKGLRNGPCGGSTAKGCYVDETRPCIWYKIYERSFKMGREERLLEVLPPLDWEKAGTETW
GDVINQAKEVGLKKVVSGLAQAETRQETWESVFKPVRQPDWWQGDDQYHAPAYEQPVSEL
ERRLKAGEFVVTAEVAPPMTVKTDKMCKNIELVRESVAAVNFTDSPSATPRMSSWACSAL
AVQHGVEPVMQIAARDRTRVGLQGEVLGASALGIRNILCLSGDSMRLSGKPRGRMDVFDL
DAVQMLWILRRMRDEGRYLDGRELKTRPQFFLGAAAAPFASEPKFQALREQKKVNAGAQF
FQTNLVFDTEQLDEWLNELGKRGILDKVYILVGITPLKSFKMARFMHDEVPGVVIPQTLL
KRMEKAEAAGNAAEEGVQIALELIERIKGKQGVNGLHLMAVGWEEIVPRIVAEAGLR
>A0A7C3WBJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MSELAHNGYKSGSNLERVLKAGHFAVTGELGPPKNHDANVIRRKAALLKGYVDTVNITDN
QTAIVRMSSIAAGVLLIQEGMDPVIQMTCRDRNRLGMQSDLLGAAALGVKNVLCLTGDHQ
SFGNHPTAKNVHDLDSIQLVRMVKDMRDESRFQCGEEIPGGGPRFFIGAAANPFGDPFDF
RPYRLAKKVAAGADFIQTQLIYDIPRFREFMKRVVDMGLHEKVFILAGVGPLKSVGMAKY
MRDQVPGMIVANEYIERMEAAVKHIDKTDKKARAEAWQQEGIRICIEQIQQIKEIEGVAG
IHIMAIEWEEAIRPIVEGAGLLPRPVIQ
>A0A832B9E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIDHINQAQKTLISFEVLPPLKGKGIGALYNHLDPLMEFKPSFINVTYHRSEHVFKKN
ADGSFQKVIVRKRPGTESICAAIMNKYNVDTVPHLICGGFSINETEDALINLHYLGIDNV
LVLRGDAAKNETSFEPEPGGHKYASDLLQQVVNLNSGIYLEDELKDTHKTKFCIGVAGYP
EKHFEAPNMATDLQYLKKKVELGADYIITQMFFDNAKYYAFVDACREIGINVPIIPGLKP
IYSRKQLTVLPKTFHIDLPTDLSNEILKCKTDAEVEKLGTEWLLHQSKDLKKSGVPVLHY
YTLGKPHVVANVVREIV
>A0A7Y3U2P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MDLKSGSNLEKVLQSGQFAVTAELGPPRGADRSVIEKKAGLLKGYGDAFNITDCQTAVVR
MSSIAAGRIVLDAGLEPIIQMTCRDRNRIAIQSDLLGAAALGAKNLLCLTGDHQKFGDHP
MAKGVFDMDSIQLIQMVKAIRDEKKFQGGQELKASEPRFFIGAAENPFADPFKFRAIRLA
KKIAAGADFIQTQIIYNINKFKDWMKMVTDMGLHEKAFILAGVAPLKSAGMARHMKHNVP
GMDVPDEVINRMTAVSAAKKGKEEGIKICLEVIEQIREIKGIAGIHIMAVEWEEAVPEIV
KETRLYPRPLL
>A0A7Y5QH84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MSVSLRQRLESDLPLLADGAMGTLLHSQGVPIDGCFDHYNVTQPDLIKGLHRAYLDAGAE
MIETNTFGANRLKLQEHGLEDQVVAINAAGVALVREAIRESGRQNAYAAGSVGPLGTGIL
PYGRLKVEDAHAIFAEQIMALVAAGADAIICETFTHIDELVIALEAARQVAAGVPVICEM
TFTRDDRTISGHLPGAVARRLADAGADVIGVNCSGGPAQIIRVVRQMKDAVPDGRFSAMP
NAGFPQTVGGRMMYPATTEYFGENALLLRAIGVSIIGGCCGTTPDHIQSMRAALDDPAHP
TPALPRLVIRSPEEEADSAAAEMPSELYHKLHNGKFLFSVEMAPPRSHNLERLIDAATLL
RDAGADVLNVADSPTARMRLSPWAACSVLQTRLGLETVLHFPVRGRNLLRVQGDLLGAHA
LGVRNLFVVMGDPTRIGDYPEAMDNYDIAPSGLIRLVKQRMNAGVDQAGNSIGQPTSFTV
GCALNMGADDPDKEIDVLCKKIEAGADFALGQPVFEPARVERFLKRYEEIVGEPLRLPVM
LGMMPLYSLRHARFIDNEIPGISIPPAILKRMESAGESAAQEGVRIAQELLSALKDYVRG
AYIIPAFGRYDLAAQVIDSVAVRS
>A0A7V3K2Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPALALNGAFEITVEVVPPAGPDPGPLLQALKPLRGLPFAAFSVATNPLAKPRLSALALS
ALIQKEVGRPAILHCTTRDHNRLSLQALLWGARALGVETVLVATGDFVALGDRARTTTVR
DVDVFGLVQMAREAGLQTGVVLDPRPESNGLRQAIRRLRRKAEAGAQFAVTQPVYDRAGA
LALAEAAGGVGLPVFLGILPLRSARHALFLHEKVAGIVVPEAVRRQMAEAADPVAEGVAL
AREMLHLAREVFAGACIMPPFDRYEVVEQVLAP
>A0A7V4MSN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MLQHLARQIRQGSGLESRERLRARLGASLAKRVDRLLFACQTCGHCLLYETAFICPLTCT
RGLRNGPCRGSNPDHCFIDRTRPCVWYRIYAKAEREGTLERLLEVNAPTDTRCRGPGAAM
TAHELCRRHGRSPRLADLILNPARYRTEWEAYHSQQRQLPWWQGDSRYHPPAYAEPVSRL
ESRLRNGRFVVSVEVAPPMEPSGRRITHLAEQLEGCADTFNFTDNPRGVARMSGLACAIH
ALASGVEPVLQIQTRYRGRYDLESEVVGACLIGVRNILCLCDDAGRLGPGPRPPAGPSDL
DAVQALWMLRRLRDEGVNVDGEAVEHHPEFFLGAIASPCATLPRYAALITEKKVNAGAQF
LQTLPVFDLHRFRDWMEALDQRNVLGKAFLIVAVAVFKSAAHARYMAEEVPGVVLPPVLR
ARVENAADPHRESIDVALETISELKRMRWVNGIHIHAPEQEEVALRLIEEAGLKDFVPQV
DVMPGNGRQAAAVRH
>A0A7Z8L7J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRLDHLFARQPQTLSFEFFPPKTDRAWHTLEDTIDQLSGLGPDFVSVTYGAGGSTRARTR
EIIEHIQAQTPLTAMAHLTCVGATKDEIRALLDEYAGAGIANILALRGDPPRGSGGFTPT
PGGCRYASELMELVAADGRFALVGAAYPEGHPEAADRFSDWKHLLHKFDAGACAAITQCV
FVEDEYLELQRWASAQRPDARIIPGILPVTDFAAVKRFCSFCGAKIPDSMSALLEPLLDQ
PVAMRAAGIQFTIALCRRLLEAGAPGIHIYALNRSTATAEIVTSLRDSGHLSQPCSS
>A0A7C7QP03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MLLPEAGKFTLTVEVVPPAGPDAEPVLAKLEALAPLSFDGFSVATNPVARPRMSALALCV
LIQHQTGRPAILHCTTRDHNRLSIQSLLWGARALGIETVLVATGDFVALGDRARTTTVRD
VDVFALVRLAREARLHTGVVLDPHPESDGLEQAVRRLERKAEAGAQIAVTQPVYDQASAR
TLAEATGHVDLPVLLGILPLRTARHAEFLHHKVAGIAVPEHVRERMSRAGDPMAEGVANA
RQMLAAARQHFAGACLMPPFDHYEVLFDILSSPLD
>N8XES8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bereziniae NIPH 3|TrEMBL
MFVFLHLYFMSQLSQYFAQNQFCCLVEYLPTKKQVLPVRESLAGFPACMTLSDRVRTDED
IAPLIAAQAYPDHIEKVLHYAGKGRDIDDFKLFLKQADLVGLRDILLLTGDKLKQHHDGQ
GQHARTRYLESVNAVMAAHQYGGFHIGVAFNPFKYTPAEQQAQYLKLHKKLNAGADYIIT
QLGFDLSALKQLQTFLAQEKYIQKTLACVMPLTLARAQFMVKHKVAGIVITPHMLEVLAQ
DQVNQCPENVYKRCALQILICQHLGYAGVHLSACHKADEQMLLEQYIEQYRDLNLSQCEI
LWNQLWQLAEGEQLRPKVAAKRIKSALNNKVKYQFLDLIHRAMFQSSFMKGVGTFIFNAS
FWNRKAAAKVLLQTEYLSKHYLLGCESCGQCRLAETLYICPETCPKGLANGPCGGTDLDR
CEFGDRECIHSVKSRLAHDVDQIQLLKEQLIPTVPIEVRGTSSWKNWYKAE
>A0A2M8PIC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thermofonsia Clade 1 bacterium|TrEMBL
EQAFEAFYEQIAALILGGVDLLILETFTDLNEIAEAVRAARAANPRVPVVASMTLTRDST
TIYGDSPREIANALAATGADVIGVNCSSGPSQLARVAQIMRQAQPEALLSVMPNGGFPEL
VNGRVMYPAAPDYFGDYAVILRDIGVTIIGGCCGTTPEHIRAMRTALDTPERKPRIVVTS
NEPSPLHTSGIPEAPTRLAQKLALGKFVTTVEMAPPRSFNAQKILASAQMLQEAGVDCID
VSDSPMARMRMSPWAVCHLIQDRLGMETILHFPTRGRNILRVQGDLLAAHALNVRNILVI
MGDPTAIGDYPEANDKYDIVPSGLIKLIKQNLNGGQDQAGNSIGQPTAFTVACALNLTPK
DLDAEIQSLRKKIEAGADFAMTQSVYEPHKVELFLKRYEALYGKLTLPILVGILPLYGAR
HAAFLNNEVPGISIPESIMARINAAGDVAPAVGVQIAAEILRDLRGMVQGAYIIPPFGKY
EMAAEIVESLAQPV
>A0A4R5VVX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus salipaludis|TrEMBL
MSFLDKLKNQILIADGAMGTLLYSFGKDSCFEELNLSHSEQIQKIHKAYIEAGADVIQTN
TYAANYLKLVRYGLEDSVKEINSAAVRNAKLAAGQDAYVLGTIGGNRGIKPDSITIEELK
RSFREQLYCLLLEGVDGLLLETFYDLEELETVLTIARKETKLPIIAQISLQEPGILQDRT
PVNDALRRLEGLGADVIGLNCRLGPHHMLLALEQIELPEHAFLSAYPNASLPAYTDGKFH
YEGDADYFRKSAQAFRNEGVRLLGGCCGTTPEHIRAFASELKNAVPIVEKVVKLKPKKIT
IDDRTPEREYPPLEKVVKERPSVIVELDPPRKLDSITKFFEGAKALKKAGIDAITLADNS
LATVRIANEALGYRVKAELGMRPLIHLACRDRNIIGLQSHLMGLHTLGMNDVLAITGDPA
RVGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTDFSIAAAFNPNVRTLEKAV
KRLEKKVEYGADYFITQPVFSEEKLIEVYENTKHLSAPIYIGLMPLTSSKNAEFLHNEVP
GIKIADSIRDRMARLNDQPQQAVREGIEITKSLIDTALDLFNGIYLITPFLRYEITAELA
AYTNQRANEIRGNFYVESTIQ
>A0A7C7VZP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
ADAVNITDNQTAIVRMSSIASAVLAMGEGLEPVVQMTCRDRNRLAIQADLLGAYALGARN
LLCLTGDHQSFGNHPTAKNAHDLDSIQLIRMVKEMRDEGRFQCGDGIKGVVPRFLIGAAI
NPFADPFEFRPYRLAKKAAAGVDFIQTQIVLDMDRFREFMKRVVDMGLHEKVYILAGIGP
LKSAGAARYMRDRVPGMRVADVYIERMQVAVKGIPKEEKKARREAWRQEGIRIAIEQVQE
IKEIEGVAGVHIMAIEWEEAVKPIVEGAGLLPRPQV
>A0A7V8VZS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIEHIKQSKSTVISFEILPPLKGKTINSIYDHLDPLMEFKPSFINVTYHRSEQVFKKK
ADGTFDKVEVRKRPGTVGICAAIMNHYKIDAVPHLICGGFSKQETESALIDLAFLGIDNV
LVLRGDAAKNETLFEPEPNGNRYALDLLKQVVDLNNGIYLEEDIRDGSKTQFCIGIAGYP
EKHFEAPNLQTDLQFIKRKTDAGADYITTQMFFDNKKYFEFVKSCRDLGIDVPIIPGLKP
ITSKKQLSVLPRTFHVDIPTALSTEILKCKTDADVALVGTEWLIDQSMELKKAGVPVLHY
YTLGKPEVICNVVKKII
>A0A7Y5QET3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTKPSDPALSFEFFPPNTPEGAARLREVRARLAAFAPEFLSVTYGAGGATRDKTLATVLE
ILAEKHTVAPHLSCVGATRESVRELLALYRGHGIRRLVALRGDVPSGMREPGDFRHASDL
VAFVRAETADWFHLEVAAYPEMHPQARSPRDDLEAFAVKVRAGADSAITQYFFNADAYLR
FRDDARRIGIDVPIVPGIMPIANFTQLARFSDACGAEIPRWIRLRLASFGDDIEAIREFG
VEVVAAMCRRLLAEGVPGLHFYTLNQSVAAVRVLEAIGLARG
>A0A2R6D087|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QH_10_70_21|TrEMBL
MSLKSRATGRQAGVEALLTDARFELMPFESFDEEIEHLPEDATIAVTTSPQLGIETTVER
TEQAAELGYDISPHIAARYVEDREQLDDIARRLTDAGVTDIFVPGGDREEPAGEFESAHD
LLVALDELGHSFEEVGITGYPEGHDFLDDETLAEAMERKEPYATYIVTQLCYDPDAVIGW
IEDLREDGFDLPVEVGIPGVMNYQRLLQISQKVGVGDSIKFLRKTTGVLGFVKQLVGSRG
IYKPDDLIDGLAPYVGDDHYDIRGVHIYTFNQTPDTEEWRHGRLE
>D4VDB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus PC510|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKDGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVEAGADYVVTQMFYDNRKYVDFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAMKCKDDKEARALGIEWCINQCRELIAYGVPGIHF
YTVGAVDNVKEVATAVY
>A0A2G6JMV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRIIDRLGRDKSSVSFEFFPPKTDAGAEHLFQVVQELQQLAPNFVSVTYGAGGSTRAKTR
EIVTRIKRETGIETMAHLTCVGHTKDELKQILDELLQADITNILALRGDLPKGQSQSRPA
EGGLAYASELIHFIKELGAPVCIGGACYPESHPESEDPATDLEMLRLKVDAGAEFLITQL
FFDNAYYYGFVERARNIGIQVPIIPGIMPITSYKQVHRFTHMCGAHIPATLFEELESVHG
NMEAVAGLGISYAIDQCRDLRKHDTPGLHLYTLNKSSATRAIVARLRHDPESRHR
>A0A3L7MN90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MHIRDVLARDGMTASFEFFPPRTDAAWNEFVASLPEFEALQPSFVSVTYGAGGSTRDRTD
ALVTRLATDTTLAPVPHLTCVGHSTAEINQILQAYASRGVSNILALRGDAPRAQTAESAD
FRHAIDLVRAVKSFNESRCHPDQRGFGIGVAGFPEGHSETPNTLVQMDHLKAKVDAGADF
IITQLFFDNNAFFDWKARCSLAGITVPVIAGLMPVTTLAGLKRMAELAAGTRFPAPLLRA
IKRCEDDAESVANVGIHWATEQARDLIDRGVDGIHFYTLNRSDATRRIYRTLGLAGRVGS
AATGNQIR
>A0A4Q3R901|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MVNDNSFPIALYQVIRMDTNAHGWQVNTPLMEFKPAFINVTYHRSESMFKKKPDGTFDKV
EVRKRPGTVGICAALMNRYQVDAVAHLICGGFTKQETEDALIDLHFLGVNNVLVLRGDAP
KNESSFEPEPGGHRYAIELMQQVNNMNNGIYIEEDLKNAVKTNFCIGVAGYPEKHFEAPN
MQTDLAFLKAKVDAGAEYIVTQMFFDNQKYFAFVKACRDAGINVPVIPGLKPITSKKQLS
IIPRTFHVDIPEALSSEILKCKNDAEVEEIGQRWLLQQSKELKAAKVPVLHYYTLGKPHV
IANVVKDL
>A0A3D4TFP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTEHIQQAKDTLISFEVLPPLKGKTIQSLYDHLDPLMEFKPSWINVTYHRSETAFKKK
TDGTFEKVEVRKRPGTVGICAAIMNHYQVDT
>A0A3E0NVX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MKISDAYGSEKFGLSFELFPPKTPAGEEQMFSHVARLTEFRPDFITCTYGAGGTTRSKTL
EVVQQVHDRFGCSVAAHLTCVGSTVEELRSFLQEASDRGIENIVALRGDPPRGETSFQPV
AGGLRYANELVALIRAEFSDFGVAVAGYPETHQEAPSAEIDLENLKRKVDAGADAVITQL
FYNNEDFWQFRDACDAAGICTPIVPGILPVTNLAQIKRITSLCGAMLPKDFLSALEGESE
AEGQFSVGVDFATRQVQGLVDGGVPGLHFYVLNKSPATSAVIEAVALPRFAA
>A0A4Y4AVY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium flevense|TrEMBL
MKVTQHIENAQGKPLFSFEIVPPQKGSNINDLYVNIDPLMEFKPPFIDVTTSREEYVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGVDAIPHVLCGGFTKEETEYLLVDCQYLNIDNL
VALRGDPMKGEKYFEPCKGGNNYAVDLVKQIKAMNAGKFLHGELPIANAPDFCVGVAGYP
EKHIEAPSLEADLKRLKEKVDAGADYIVTQMFFDNQRYFKFVEAARAIGITVPIIPGIKP
VAVKRHLQLLPQVFWLDMPESLISEIENAKDNAAVRQIGVEFAVQQSKELIEFGVPCLHY
YSMGKSDNIHKIASEIF
>A0A3L7P690|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSKRLKDLLATGKPVWSFEVFPPKTPAGLESMYGAVDRLMTFKPVYFSCTYGAGGSTQGP
TLDICTEIMRRHQVATMAHLTCVGLTVDSLRDFLRQARERGIQNIMALRGDPPKGQEGFQ
KIEGGLGYASDLVGLIRSEFPEMGIGVGGYPETHQEATSPEDDLRHLKTKVDAGADAVVC
QLFYNNDDYFRFVDRCHLINIRIPLVPGLLPIVNFPQIQRITALCGAKLPGSLYAELEKH
QNDPAATAEIGADHARRQTEGLIQKGAPGVHFYVLNQSEAAYQALKGLGVA
>A0A1Y0MGA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella sp. PC-19|TrEMBL
MKVTEHINNGNGDSQFSFEILPPLKGQDIQSIFDNIDPLMEFKPPFIDVTYHREEYTFKD
VGNGLLKKQIVKKRPGTVGICAAIQNKYGVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKTETYFKPEPEGHAYASELVSQISDLNNGIYLDDELQNCSKTNFCVGVGAY
PEKHMEAPSLESDIHFLKKKIKNGAEYVVTQMFFDNQKYFDFVDKCRKAGIEVPIIPGLK
PISTKKQLNLLPHRFYVDLPEDLVIEVIKCKNNSQVREVGIEWCIAQSKELQDAGIPVLH
YYSMGKSSNIKEVAKAVF
>A0A2D6W8E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MLELSVEFFPPRTGEGISRFNKAADDLVPLGFGFASVTYGAGGSTREGTLTAARELKKRF
KEGVPHVSCYGSDEESIYELLKTYSNDGFSRLVILRGDLPSGYGGLGEFKNAVDLVRFVR
REFGDQFKIEVAA
>A0A3M2CPH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MHIQDLFKQSPTLFSFEFFPPRSPEQAETLYEHMVRLEKLRPSFVSVTYGAGGTTRELTR
DLVLRAQNQTGLTTVPHMTCVKQSEAELTDLIGAYARHGVSNILALRGDPPNGQPHDWGA
ERFRYASELVSFIKEQGPKLGHPDRRGFGVGVAGFPEGHPACPNRMLEMDYLKAKVDAGA
DFIITQMFFDNRDFYDFRDRCTLAGIRIPIIAGIMPVQSVAGMRRMAELALGMRYPAPML
RALRRTDGSDESIRRVGIHWATEQCRDLLDHGVQGIHFYTLNKSGATTEIYKTLGVSHSG
QLLEGNDLGI
>V3P8B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. MGH 24|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELQAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A4Q2KQ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces albus|TrEMBL
MAETGSAAEGADCRPRPPISFELFPPRTDAAALALGRTIDRLAEADPAFISVTFGAGGTS
RDRSLTVLRYLLAHTNVEPMAHLTCVGSSHSEANRLVREFLDAGVTSFLALRGDPPVGAD
PDAGIGDLASAAELVQLIHRVQEEREPFAQVGMPGMPGASRIRERARPERVAVAAFPTGH
PRSRGIAHDVDILLAKEISGATLAITQLFWRADDYLTFVDRARAGGVTIPIVPGIMPVTT
PARLARLTELTGVEPPAELAIDLEIEPDAAAQAELGITFAARLAAAVLEGGAPGLHLYTY
NRHEVVLEVLNRLDLRNPDQLVNERNTTQR
>A0A167TZC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium fryxellicola|TrEMBL
MKVTQHIEDASGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTQEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKKGGNDFAVDLVKQINQLNCGKYLHDVMDVDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVEAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIQAVDQCKNNSDIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIKQIASKVF
>A0A2E7QQN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDIFAEAREAGEVVVSCEFFPTKTPEGERSLLEKTIPRLKTVGPAFCSVTYGAGGS
TRGKTLDIVETIQCEHGLPAMAHLTCVGSTRDDIQGFLNEAQSRGIRNILALRGDPPAGE
VEFVKPEGGFEFSYQLVEAIRGHGGFSIGTAGFPEGHIACTEGREVDWRRLKEKVDCGAD
FVITQLFFDNDDFFRFRDHLRGLGMDKPITAGIIPVLSGQQIRRFTSLCGARLPSPMTDR
LDELGDDNDAVREFGIEYATKQCRALLESGVEGLHFYTLNKSNSTVRILENLGLAKDLS
>A0A2V4KZ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas alcaligenes|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLAGYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVGVPTAPHLSCVGDNKAELRSLLSQYKNSGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGDHFHIEVAAYPEVHPQARSYEDDLKNFVRKCQAGADSAITQYFFSADCYFY
FVERVRKLGVTLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDLESIQAFG
EQVVTEMCERLLAGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2L1GLW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus oralis|TrEMBL
MRIPEAIAQKRPFVSLEFFPPKKREDWPAFLQTARELAGLKPLFVSVTYGAGGSSRSNTL
EICRLLAERCGFTVMPHLTGVLASPESIDRFLDEIKAIGIDNVLALRGDRPAAFTGADEE
LFAAFPHAADLIRHIREHSPGLAVGTAAFPEGHAEARSFSSDLKVMRDKFQSGADFGITQ
LFFDNRSYFDYVERLGELGVTAPVIPGILPVRSLASLRFTLKLCNARVPGSLINELLDAE
EREGPKAAFEVGIAHARSQVRELFERGAPGVHLYTLNRADMCTRLLDGLL
>A0A651FXM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSFMRLDHILQRGKRCLSYEFFPPKSDRAWYTLEDTITQLAGLGPDFVSVTYGAGGSTRA
KTREVIEHIQRNSPLTAMAHLTCVGATVAEIRGLLDEYHHAGIENILALRGDPPRDQGAF
TVTPGGCAHSNELLQVVAADGRFASVGAAYPEGHPDSPSREEDWGHLLEKFDNGACAAIT
QCIFDSKDYCELLQWVEHRRKGSTIIPGILTVVDYPAIERFSSFCGATIPQALKELMEPL
QERPSAARAAGIAYTIHLCRELLDLGAPGIHIYALNRSTAAAEITTALRDSGHLPQPYTE
TELRRGPLS
>A0A3M1UXP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MGSRTGERRVDGNELSGQKVFQPRTLRELYRSGETVVSIEVFPPKNAAGDAALFETLNRL
VPYQPQFISCTYGAGGGTRERTVEICRTIQQDYGVTATAHYTCVGATREELEQGLAQIYR
AGIRNIMALRGDPPRGEKSFRPVPGGLVHANELVALIRERYTDVGIGVAGYPEKHQEAPD
METDLRNLKRKVDAGADAVFTQLFFVNAHFLRFRDACERLGIRVPIVPGIMPVTEYGRIK
RITELCGAYFPPALAERLQALEGDPDGQFAAGVDWAVRQCEELLQAGVPGFHFYALNRSP
ACEEILRRLGVASRAA
>A0A1V5DR19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp. PtaU1.Bin162|TrEMBL
MTNSIMRELGASVLIGSGAIGTCLREKSGRSDEPVELLNLREPEMVKNLHAAYRSAGSQI
LVTNTFAANAVVMGDAGVAELCEEINRAGVALAREAGGEECLIWASVGPLGLGLRLDDYP
ADALLDIYRRQCGALGTADALLLETFVDVREARAALFAARETGLPVIFQIGNTGGGSQRW
NRVNQLLDEAHRAGVVAVGTNCYHPDEIVRVASYIGTYTNLPLTASPNAGHPRIERGAVK
YEFTPDDFATAAVALSAAGAAVIGGCCGTTPEHISRMSGVLGRRAVALRPRMEIFPERSR
ALPEKPDTEANPIRSMMKSKHFIISVEIRADRRQSLSEIVQGASKVAAAGADMFDVPDNP
GATVGRDATVTAARLQNTLQIPSICHFGVTQSNLMRLHSTLLGCWDSGLRGLLAVTGDAP
SMGHLGSLAHRVVDMRSSVELLRLIRGLREGKIINGEGLADPPDFCAGCAVGKPIPAQIR
WLQTKIAAGAEFVFSQPVFTLDDYKRLRDAVAGLPIRLFAGIMPLISLRSAVFMASGRIP
GISVPADVVTSFEHYESPADQHLFGLDNACELAAGIAQDGAGLYLIMPFGKSSYDDAAKI
VRRVRKQRVD
>A0A432LAT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus antri|TrEMBL
MGLLEALKSKVLTADGAMGTLLYSYGLDHCHEEMNIVRPELIEKIHSEYIAAGADVIQTN
TYGANVIKLARYGLESKVQEINEAAVRLAKNAASSGNQFVIGSIGGIRGVRKNEATLNEI
LDAIREQAEILIQGQIDGLLLETYYDFEELTETIKMLRDLTSLPIIAQVSMHEPGVLQNG
MLLNDALQELERLGADIVGVNCRLGPHHTIQAFEGVELPQKAFLSAYPNASLLDIDEGRV
IYESEIDYFARAAIQLRNQGVRLIGGCCGTTPKHIEAVKKQLEKLTPLEEKQAKQQQIVS
IQEPDPTRQEPLHEKVKRERSVIVELDTPRHLEIDGFVEGAKSLYNEGADIIMMADNSLA
SPRISNIAMGSILKLQHGIRTMPHITCRDRNLIGLQSHLMGLNALGLHDILAVTGDPTKV
GDFPGATSVYDVSSMELVSLIKQLNEGISFSGKALRKKANFSVAAAFNPNVRVLDRAVSR
LEKKIEHGADYFISQPVYSSEKIEEIYEATKHLSAPIYIGIMPLTSFRSAEFLHHEVPGI
KLSDEVLERMKACEGDKVREAAEGVAIAKELLDTATKHFNGIYLITPFLRYDLTIQLMQY
IKQLDKQNEGVKANV
>A0A7G7W7U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp. S2-20-2|TrEMBL
MKVTEHLNRAEGKTLFSFEVLPPKKGENIQNLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRKRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGNFIPNPDGHAYACDLIGQVADLNKGAYLDEKQDDVWATSFCIGTAGY
PEKHFESPNYGADLRYLKHKVDRGADYIVTQMFFDNEQFFAFEKRCREAGITVPIIPGLK
PLTTKSQLTMLPRAFYLNIPEELADAVHLAPDNTAAREIGIEWCINQSKELMAHGVPVLH
YYSMGKSESIRRVAAALF
>A0A5S3UVT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas rubra|TrEMBL
MALSLQEKILDPNQGVYLIGTTPPKSGTEQDKVERIATKLLDRLHEIEYDGVIIYDIQDE
SSRTNVPRPFPFKETVDPCEYSRLVKSLSKLDVITYKSVAQRDSAEFNQWLSTTKQEFGL
NNLVLVGSPSSQGKINLPLPEAYQALAQHEESFFLGGVTIAERHASKRNEHERLIEKTTQ
GCEFFISQAVYDAQATIDLITSYARTCKQQGIAPKRLILTFTPCGGEKTLQFMEWLGISV
PEATKWRMLDADNTLSESIRICRENLDSILRSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKATMELTLAEKQIA
>B7S0R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine gamma proteobacterium HTCC2148|TrEMBL
MAKPRISFEYFPPKTEAGKDKLLNMTTTALNELNPEFFSITYGAGGTTRGATLGVVSAMS
EAGIDVAPHLSFGGDDEDAVNDLLDTYKALGIKRLVALRGDIPSGMGTANQLVHASELVA
LVRERSGDHFEIEVAAYPEIHPESKSYESDVQFLKTKLDAGANSAISQYFYNVEAYFYYL
DQCAAAGIDKPIYAGIMPITNYENLARFSHNCGAEIPRWICKRMESYGNDTDSIRKFGLE
VVTQLCQTLLDSGAPGIHFYTMNQVEPTSTIYKNLGL
>A0A1I5S494|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sagittaria|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMTVARQLAGYNPDFFSCTYGAGGSTRDRTLHTVLQLD
GEVKVPTAPHLSCVGDSKAELGELLNLYQNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGEHFHIEVAAYPEVHPQARSFEDDLLNFVRKVQAGADSAITQYFFNADCYFY
FVERVRKLGVKIPIVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDLESIQAFG
EQVVTEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1Y5GNP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium 45_16_T64|TrEMBL
MESQKKYKSRFSFEFFPPKTDVGVQKLKVVREQLAEKNPAFFSVTYGAGGSTRDRTVDTV
LDIQKSTGISTAPHLSCVGDSREQLRELIQHYKKNGIERIVTLRGDLPSGMGASSGELKY
ASDLVAFIREETGDHFHLEVAAYPEMHPQAASMDADLLAFKAKVDAGASSAITQYFYSVD
SYKFFVDSCEKMGIDIPLVVGIMPITNHDNLMRFSNMCGAEIPRWIRTRIENHSTDLDYI
TKFGEEVVTGLCEQLLDLGAPGFHFYTLNQTEPSLSIWNNLDLSNR
>A0A5N1ISX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adhaeribacter soli|TrEMBL
MKITERLKTLTKPAFSFEVLPGAGVSAAESLTPYQNLLDQQPLFVDIPFHPHKTATGFNS
QKHTLSKAAPSKEALSRELLITHGLEPLPHLLCKGFSPEETAKTLKDLQQLHVQNLLLLR
GDHQQDNGRPDQHQYAFQLVKQVREFNEQVKAADPTQTGFCIGVAGYPEPTRENPDMDLN
IQYLKQKVDAGADFILTQLFFDNACFFTFEKRCREAGIMVPIIPGICPLTSFRVLKLLPG
FFQVKLPERLQELVDEATDESQLAEIGIEWAIRQAQELYHGDTECVHFFGLSNPEAVEEV
VRVVL
>A0A2S4LA92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolypocladium paradoxum|TrEMBL
MHIADMLTEAEKSGQPSFSFEYFPPKTAQGVQNLYERIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLEQVNDALSKAYKAGCTNILALRGDPPRDQEK
WTATDGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGCDDNKNEEELLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGKVRERGITIPILPGIMPIATYASFLRRANHMQCKVPDHWMNAL
EPVKNDDVAVREIGKTLVAEMCRKLLANGIFHLHFYTMNLAQATRMVLEELSWAPSAERP
LQPALPWKQSKGLGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTTIRDIANTFVRYLDQKIDSLPWSESPLTGEADAIRQDLVA
LNKRGFLTINSQPAVDGVRSSHPVHGWGPSNGYVYQKAYLELLVPPSILTEIISRIESQS
NLTYYAVTKDGDLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
AHCFDSNTPSRALIETIMNEWYLVNIVNNDFHENHTIFELFRDIEVPDVDGPQAA
>A0A0R2VFV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium BACL12 MAG-120813-bin55|TrEMBL
MKVTERIHQATSTLLSFEVLPPLKGKSVQSIYDILDPLMTFNPAFVNVTYHRSEYMYKKR
SEGIFEKIYTRKRPGTVGICAAIQFKYKVDAVAHLICGGFTKEDTEDALVDLWFLDIENV
LLLRGDAARNERVFEPEPGGHAHAIDLVKQVVNMNKGLYLEEEHQGGKTDFNIGIAGYPE
KHFESPNMSTDLKVLKEKVDAGAHYIVTQMFFDNQKFFAFEKKCREAGIHVPIIPGLKPL
TAAAQINTIPRIFHVDIPEALADAVEKAGSAEAVQKVGTDWCVEQSRELKAAGVPCLHYY
TMGKIDVMRSIMQEVF
>A0A4R6ID41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter duraquae|TrEMBL
MKITDHIKNAQGKTLFSFELLPPMKGQGIQGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HASGLLEKVSYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARRSDASFIPTPDGHAYASELLQHVVDMNNGKYLHEHIDNSEKTDFCIGIAGY
PEKHFEAPNLQTDFKYLKHKVDLGAEFIVTQMFFDVNAYKTFVEKCRENGINVPVIPGLK
PITSSKQLISLPKTFHLDIPMELSEAITACSSEADVREVGIEWMIEQCKQLKALGAPVLH
FYTMGKSGPTKKIAQAIF
>A0A3E0VDR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Subtercola boreus|TrEMBL
MTGKDIPGLLEAKDAIPAGSKVNVTFLGNEDLAMRIAASKAVIEAGFVPVPHISARRLSS
EAQLEEYLGALQEIGASGHVFAVGGDPAIPEGPYEDSLAVIRSGVLQKYGVREVSIAGYP
EGHPDIPGDVLWKALEDKSKALSEQGLDATILTQFAFDTTPVVEWIREVRTRGIDTPIRV
GTPGPAGIKRLLSFARRFGVGANTMIVKKYGFSLTNLMGTAGPERFVSELGDLLAEDAGS
GPVSLHFYTFGGLKATADWARAFSADTAL
>A0A427ZY83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTFAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNXAATAYHIYKATHALFNHNPSVQSF
>A0A4Y9F1Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia nasimurium|TrEMBL
MSTHIPALSYELFPPRSSASCESLLTTIDQLAPTNPDYVSVTYSGDRARKQKTLALLDHL
VHETRLTPLAHLTCVGHTAEELEAAVRRILAIGVRGFLALRGDLPLGNTQAPDIPFARSL
VELIRRVETQDFAHLAAGRVAVGVAAYPSRHPESSSELQDIEILLSKERAGADFAITQVF
FEATRYESLVQRARTAGVTLPLIPGIMPVTSLRRLTTLCSLAGLPVPQQLAYDLETASGD
AQRHRIGVEFGVRLLQESLDAGAPGIHFYTFNEHAAVLDVLERVDLPRYSTRFENPLAEL
TYA
>A0A0G4PJW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium camemberti FM 013|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEAAENGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNTDVDQLIDHLKEKVDAGSSF
VVTQMFYDAENFIEWLKKCRAKGITVPIIPGIMPIQTYASFIRRSSWTKVKVPPQWMEAL
EPVKNDDSAVRDIGKTLIADMCRKLVAAGIKHLHFYTMNLAQATQLVLKELDLSPSDESP
IQRALPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISDIFVNFLTGKLDRLPWSDSPITTEAHDIQEDLLN
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLLDELITRIEKND
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCHDAASPSRKLIQHVMDDWYLVNIVDNDFHRSNAVFELFDGLEIKDLNVEMTGKPLTNG
HAEQNGVAAN
>H0Q523|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azoarcus sp. KH32C|TrEMBL
MSADYPFSVEIFPAQTSEGRLRLADTVRRLVAQGPEFISVTYGAGGCTREASLAALQLVR
AAGGVAVPHISAAGASRDDIRSLLAEYEALDVHRLVVLRGDPSSGLPGRGAFPHAVELVR
FIREETGSRYHIDVAAYPETHPQARSAEHDLACFKAKIEAGANAAITQFFFNADAYEDFL
ERCARQGINVPVVPGVMPVASFSRLLRFSDAHGIEIPTWIRRRVADFGDDAESIRAFGVD
VVRRLCARLLALGAPGIHYFSRNDWQRIADIGSGLRIPASSRV
>A0A2P5FKI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trema orientale|TrEMBL
SHIYCQLVLVTPSSSSSYLVLFDFSHRVNDCRRVGITCPIVPGIMPINTYRGFLRMTGIP
AEITAALEPIKDNDEAVKSYGIHLGTEICKKILANGISTLHLYTFNVEKSALAILMNLGL
IEERKVSRGISVSRIVEEAEAKTG
>A0A7V2SNT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSENAFNVARDSKGFTISFEAFPPMNEAGQGKLLDVAKNLESFAPEFFSVTYGAGGGTQE
RTLNTLAEISRKTGHNLAGHLTCVGATKEHTNAVAAQYRKMGVNRIVALRGDTPVGVDKY
EPHPGGYKNAADLVAGLKEMGGFDISVGAYPESHPDSPSKSADLDNLKAKFDAGADRAIT
QFFFDNHIFYDFISDTQAHGITGPVVPGILLIHDFWKVKRFAKMCQTDVPDWLEARFAGL
EDDLAAQRLVAVSIAVEQVLDMAANGVRHFHFYTMNKSDLAVAVCRSLGLKPARDMQSVA
>A0A7C4E993|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MRITEIFKKQKHTFSFEFFPPKDEITAVEFGINAGQLMRLQPSFISVTYGAGGSTQERTF
NLVDLFQNKLGLTCMAHYTCVNASAQKVSADLDYLYSRNIENLMLLRGDPPKGQQSFIAT
SADFTHASDLIRLAKSQNRFSIGAACYPEMHIESRDTDEDMQFVKEKTEAGADFLVTQMF
FDNSFYYRFVERARAAGITCRIIPGIIPVINYHQIKKFVEVSNATIPRQLATILESYKDN
EKKSYQIGVDLAINQCEDLLNHGAPGIHFYTLNKSRAVIDIYESLSLRYKC
>A0A2U3BA92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio albus|TrEMBL
MGYTHAGHIDALNQNIAELSDINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKEIKEQTGLIAAPHLTCIDATRDELKAIAEDYWRNGIRNIVALRGDI
PPGGGTPEMYASDLVALLKSLHDFDLSVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVSAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMARQFEG
LDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQK
>A0A4P6PZR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomonospora litoralis|TrEMBL
MPGSPTRNGSAPAAATRPRDIRELLKAGEPTFSFEFFPPKTDEGLRKLWQVIRQIEALAP
SFVSVTYGAGGGTRDLTVEITEQLQTDTTLLPVAHFCAVNHSVSELRHLIGRFASVGVNN
ILALRGDPPGDPLGEWVKHPEGLEYADELVRLIKELGDFSVGVAAFPYKHPRSPDIESDT
KYLVQKCRAGADYAITQMFFDPEDYLRLRDRVAAAGCDTPIIPEIMPVVKYSTIGMSEQL
SGAPFPRHLAAEFDKVADDPESVRKLGIEQAQRMCERLLDEGAPGIHFITFNQSTATREI
YEQVAYDRLPATAGARP
>A0A6N7H1P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MNARPSRFMNAGADRRMHVSFEFFPPKTAEMEATLWDSITRLAPLRPNFVSVTYGAGGST
RERTHATVKRILGETALIPAAHLTCVAATKPEIDEVIRGYHEAGVRHIVALRGDPIGGIG
EKYAPHPGGYKNGADLVVGIRRLAPDVDVSVSAYPEKHPDSPTVAADIDMLKAKVDAGAT
RAITQFFFENDQYFRYLDRVRAAGINVPIVPGILPVQNFKQTKNFAARTGASVPDWLAER
FDGLDDDAATRKLIAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAVCHLLGLRPAEQA
AA
>A0A7C2QSF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MPAQRHNQLRDSLQSGRFAITAEIVPPLSCDRADLLAKVAPLRGVADAVNVTDGAGARAH
MGSLAAAALLLESGIEPILQLTCRDRNRIALQGELLGSAALGIENLLLLKGDDPAGGDQP
EAKAVFDLDSLTLTEIARGIRDRRELPSGQKVSGSANFLIGTADAPVDPPPGWRPTRLKS
KIDAGAQFAQTQFCMDAGVVRRYAQCLADNGLGGFRLLVGLAPIRSARSARWIREKLPGS
IVPDRVIARLEAAAEPVREGRRICLELIEELCEVPGAAGVHIMAPGNDAGLAEVVAEARG
IALARGGRAAERLRGPGEAASAGGRPLHPD
>A0A3E0QIJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHLKRANGKTLFSVEILPPLKGKSIQSIYDILDPMMEFKPAFIDVTYHREEYVYKK
RENGLLEKFSMRKRPGTVGICAAIINHYKVDTVPHIICGGFAKEETENALIDLNFLGIDN
VLLIRGDAIKSEAVFVPHPKGHNFAIDLVKQVVNMNQGMYLDEELNDVVPSKFCIGVAGY
PEKHFEAPNMRSDMKHLKAKIDAGADYVVTQMFFDNKKYFDFVEKCREAGINVPIIPGLK
PLTSIKQCTVLPKIFHVDIPEDLDDAIAQCKSDKDARKIGIDWCIQQSKELMKAGVPCLH
YYTMGNADNTVSIAKELF
>A0A516H8E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassotalea sp. PS06|TrEMBL
MNYRSARQLDSLNRTVSELSADLQVSFEFFPPNSPEMETTLWNSIERLAPLNPNFVSVTY
GAGSGTRDRTHGVIKRIQQDTGLIAAPHLTCIDASREELVQIAKDYWQSGVRHIVALRGD
LPDSDKKPDMYASDLVSLLKDVEDFEISVAAYPETHPEAPNAQFDLLNLKRKVEAGANRA
ITQFFFDIDSYLRYRDRCVSVGIDVEIVPGILPVSNFNTLKRFAGLTNVHVPNWMYNMYE
GLEDDPTTRNLVGASIAMDQVKILRSEGVEHFHFYTLNRSELTYAICHTLGIRP
>A0A2W4UNN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MNAFRPSRHGSRRPKVSFEFFPPKSDEMEVALWESVRRLEPLGPSFVSVTYGAGGSTRER
THATVKRMVEETGFKPAAHLTCVSASRGEVDEVIRAYWEAGVRHVVALRGDPAGGLGTTY
EPHPQGYHQTSDLVAGLKRIGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRAAGIDIPILPGIVPVQNFKQTANFARKTGASVPQWLADRFDGL
EDDAATRRLVAAAVCAEQALDLIDRGATDLHFYTMNKADLVYAICHLVGVKPEKAEPQAA
AAE
>A0A2P5BP95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trema orientale|TrEMBL
MKVIEKIREAVGVSEGYQNGTTQKNVVFSFEFFPPKTEDGVDNLFERMERMVAHNPAFCD
ITWGAGGSTADLTLDIANRMQNSVCVETMMHLTCTNMPLDRIDHALSTIKSNGLQNVLAL
RGDPPHGQDKFVQIQGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIGPDGVASLE
AYQSDLAYLKRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGF
LRMTGFCKTKIPAEITAALEPIKDNDEAVKSYGIHLGTEMCKKILANGIRTLHLYTLNME
KSALAILMNLGLIEERKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTTGWDQYP
QGRWGDSHNPSYGALTDYQFMRPRSRDKKLLEEWGIPLKNIEDINEQFKKLCIGKLKSSP
WSELDGLQPETKIINEQLGKINTKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYL
EFFCTKDTLNALVDKCSRSFPSLTYMAVNKEGRWLSNVDQTAVNAVTWGVFPGKEIIQPT
VVDPASFTVWKDEAFQIWSRGWARLYPEDDPSRKLLEEVENSYFLVSLVDNDYVHGDIFA
TFNEL
>A0A5Q4E433|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MTIPELIAQSNGSRRISYELLPPVKGSSIDTIFSTIDKLMPFNPPFINITYHREEISFIK
QKDGSLIPSVVRKRPGTVGIAAAIQAKYKVDVVPHIICGGFSRQETEDALIDLDFLGIKN
LLVVRGDGDKITGRFKPNPQGHRYASGLIEQIIAMNNGIYHEQYVENPTHTKFSLGVAGY
PEKHAESPNADEDLLFLKQKVEKGAEYIVTQMFFDNEVFFNFVKRCRDAGIQVPIIPGLK
PVSIKEHLHVLPRTFNLSIPSALVKEINKCKDNAEIRELGAEWTSNQIKELMENGHNFVH
IYTMGKVDHICRISEKVLFDK
>A0A5D4HD65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium phlebotomi|TrEMBL
MKIVDHIKNANGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYLYKQ
HVSGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDPDFVPTPGGHAYATDLLQQVVDMNKGKYLHEDIESSAKTDFCIGVAGY
PEKHFESPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKRQLITLPKIFHLDIPEELSDAVEDCKTNADVRQVGEEWLVEQCKELIKFGAPVLH
FYTMSNPGPTKKIVERLV
>A0A4P5TR44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKITDHISGANKTLFSFEILPPLKGASIKELFASIDPLMAFQPSFIDVTYHREDYVLKKR
ADGSYDRISTKKRPGTVAICAALQNHYKIDAVPHLICGGFSKEDTENALIELSFLGIDNI
LALRGDNRKGDSHFEPENNGNKDTLDLIRQIQNMNAGIYLDEEISNSNESNFCTGAGCYP
EKHADAPNMESDLKYLKRKVDAGAKFLVTQMFFDNQHYFNFVDSCRSAGITVPIIPGIKP
ITTRKQLSILPNLFHMDIPFALTNEIDQCKDDKHIADIGVAWAIEQCKELVAKGAPVLHF
YTMGKSTQTKKICEAIF
>A0A522F527|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVVDHIKQSKSTLFSIEILPPLKGKSIQSIYNIIDPLQDFKPSFVDVTYHREEYIYKKR
EGGYLEKVSTRKRPGTVGICAAIMNRYKIDTVPHIICGGFTKEETESALIDLQFLGIDNV
LVLRGDAVKNERSFIPEPGGNAYAIDLVKQAVNMNKGSYLHEEDMVEVTPTNFCIGVAGY
PEKHFEAPNMTSDLRHLKTKVDAGAQYVVTQMFYDNQKYFDFVKKCREMDINVPIIPGLK
VLTTKSQSSILPKTFYIDIPQDLMEAVEKCKNDSEAKEVGIEWAIRQSKELIKFGAPVLH
FYTMGSAEPVRRVVSTVF
>A0A2A3D9U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3860|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILHETTLTPAAHMTCVDAARHQVDAVIQEFAGMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALLPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A2W4P9U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
HFLGIDNVLVLQGDAIKTESRFIPEPGGHHYASELLQQVVAMNQGRYLDDTLQNPTPTNF
CIGVAGYPEKHYCAPNLTTDLKYLKLKVDLGANYVVTQMFFDNKKYFDFVARCREIGINV
PIIPGIKPITSKAQTTVLPKVFHIDIPEDLADAIDKCKNNAEAKEVGIEWCIQQSRELIK
YGVPTLHFYSMGKSDPIYRIAKELF
>A0A365N7C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella intermedia|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIHDIALLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDSEPIANGTAATAVAN
>A0A431QST7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MTGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFRTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>R0LJR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis 11/5|TrEMBL
MSRQTPSLSFEVFPPNPEVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>N1UDE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira weilii str. Ecochallenge|TrEMBL
MNSIFENFLNLVRKAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEVEHRP
EEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A431PI45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MFNALHPTAAGKRFKISYEFFPPKSAEMEKQLWESVKRLEALKPHFVSVTYGAGGSTRER
THAIVERIARETAMKPAAHLTCVSSSAAEIEDILREYWAAGVRHIVALRGDPPTGVGTKF
EPNPEGYASSSDLVRGIRRLHDFEISVSTYPEGHPESASIEQDLDALEAKIDAGATRAIT
QFFFDNDIYFRFLDKARARGIKIPIVPGIMPIRNFRQVASFAAKAGASVPRWVAERFEGL
DDDPETRALVAATTAVEQVMGLARAGVDEFHFYTNNRADMVFAICHLLGVRPVREKVNA
>A0A249K9M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nanopelagicus hibericus|TrEMBL
MSNDQSAPTLSVEFFPPKDISGEERLWQVLAQLAPLKPDFVSVTYGAGGSTRDRTIRVTT
EITARTSIPTVAHLTCVGSTKSELSNVLDQYKKAGIESILALRGDPPGGPRSNWQSIPGG
FDHADQLVELAIESKDLKVGVAAFPDGHPSSNFDLDKDIEVLLRKEELGASFATTQFFFD
VNKWQQLVERLRKRGSKLPIIAGILPITNLKQLNRMVELSGMQIPEQILTRFKDHSEDVN
VVREIGIDIATEMGSKLLEMNVPGIHFYTMNSADSTIKIARNLGLVKR
>G1X2G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491)|TrEMBL
MQEKITDKIKALPKDATYFSLEFFPPKTPAGLQNLHARLDRMAKGLRPLFVNVTWGAGGS
TATKSLELASLCQSHGLTTVLHLTCTNMSKSVLDDALENAKLMGIRNVLALRGDEPRQHE
YLDVTEQVRNGSGENEFVYAIDLVRYIRKQYGEYFAIGVAAYPEGYAETAYPVAQDTARD
LPYLREKTAAGADFIMTQFFYDVEAYISFEKVLRNDESGVFKDIPIIPGLMPVQSYQIFR
RTTKLCSVKVPGTISSRIESVKADDEMVKEHGIQVLTEMIGKIRSSTESDGGLPRGFHFY
TLNLEKAVAFIVERCNLIPEIPTSNEMAVEDEDDEGPGLLTVNGGGASIPRRSRRTSSII
SDPHNRVIVDTVSSARSELQAEAGEAGVPKILDPGSQEGNLAISEGEGSLGREATWDDFP
NGRWGDARSPAFGEIDGYGVSLHRTPTEALKLWGKPTSTKDISDLFVKNSKGELEAMPWS
EDILNPESFLITEELVKMNAKGWWTVASQPAVNSAKSDHPTFGWGPKNGFVFQKAFVEFF
ILDEEWTELKKKLENEGKEDVSFYAGNKAGDFQTNLASDSSLNAVTWGAFPGKEIITPTI
IEEVSFRAWRDEAFDIWSEWQRIYPLSSATSKLLGELKNKLWLVTIIHHDFVNADGLWKD
ILGL
>A0A1F9APD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_61_14|TrEMBL
MKSGSNLERVITAGQFAVTAEIGPPMDANPEVVIEKAKVLKGYADAFNITDCQTAVVRIS
SIAAAVLVLREGLEPVMQMTCRDRNRIAIQADLLGAAALGLKNCLCIAGDHQSFSAAGRL
KGHPGAKNVYDVDSIQLVNILKIMRDEGRQQGGDPLKTRPQFFIGAAWTPLGDPIEFRPI
RLGKKAKAGADFIQTQGIFDVEAFARQMEKVRNLGLHEQTAILGGIIVPRSMMMMKYMNQ
NVAGVSIPEKLIARMAKAKESAGADKEKAKQLQEEEGTKLAVELIEQVRAIPGIKGVHVQ
AIEWETQIPEIVKRAGLYPRPSAPA
>A0A1J9TS87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus albus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVVQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTEKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAALNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7S7LU94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfurimonas baltica|TrEMBL
MFDELINKLKNDTYITLETTPGHSPVFTPTVDKIAELGLDKLVDGFTTTDNPLAKLKYNA
LFAAKILQDRFNKPVIATMSMRDRNKIALQSDLLGANEVDIRAILALTGDPATISDQPHA
KGVFEGDSSLLLDIISAFNSGMNYAGKPLAVKPKTLYPFAVVNSYAKNPKTLQKKIQKKI
KHGAIGIITQPVYDVQNAIQLLELRDAANAECCSEDKKGELIIGLFPITKLRTAQFLSAH
VPGINVPNSWLEALREANLKGADEEYKVGFELSKKLFDDVKKLHPKIHLMTANQFTLAKD
LLS
>A0A1Y6G8E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. OV166|TrEMBL
MSFLDKLKNQILIADGAMGTLLYSFGKDSCLEELNLSQPGHIQTIHKAYIDAGADVIQTN
TYAANYLKLQRYGLEDSVKEINSAAVSIAKKAAAQNDTYVLGTIGGNRGIKPDSISIEEL
KRSFREQLYCLLLEGVDGLLLETFYDFEELETVLTIARKETKLPIIAQVSHQEPGLMQDR
TPVNDALKRLEGLGADVVGLNCRLGPHHMLLALEQIELPAHAFLSAYPNASLPAYTDGKF
HYEGDADYFRNSAKAFRNQGVRLLGGCCGTTPDHIRAYASELKNSVPVTEKIVKLKPKKI
IVESHSSKREYTPLQDIVKERPSVIVELDPPRKLDTTKFFQGAKALKEAGIDSITLADNS
LATVRISNESLGYLVKQDLGMRPLIHIACRDRNIIGLQSHLMGLHTLGMNDVLAITGDPA
RVGDFPGASSVYDVSSFELIQMIKQLNEGLSFSGKDLGQKTDFSIAAAFNPNVRSLEKAV
KRLEKKVHYGADYFISQPVFSEEKLLEVYEHTKHLDAPIYIGLMPLISSKNAEFLHNEVP
GIKIADSIRQRMAQLNDQPLQAAREGIAITKSLIDAALDLFNGIYLITPFLRYELTAELA
LYTRQRASELRRSTYAENTIY
>A0A832MUG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriia bacterium|TrEMBL
MKVTEHIKKANGKTLFSFEILPPLKGQNIQSIYKNVDPLIEFNPSFIDVTYHREEYIFKE
LENGLLQKQITRKRPGTVGICAALQYKYKVDAVPHILCGGFTKEDTENFLIDLNFLEIDN
VMALRGDPVKSETYFKPEKDGHQYPAELVSQISDLNAGKYLDEELLNTSKTDFCIGVGAY
PEKHLESPSLDADIHFLKRKIKAGADYIVTQMFFDNQKYFEFVQRCRKAGITIPIIPGLK
PIAVKKHLNIIPHRFNVDIPNELIMQVVKCKDNKEVRQVGVEWAIAQGKELIKAGVPALH
FYSMGKSDNIKAIASALF
>A0A679FSB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus subterraneus|TrEMBL
MGLLDELKQRVLIADGAMGTLLYSHGVDRCFEELNLSKPEDIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSAVPLDEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPVIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYYMLQSLEEVPLPTRAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLLGGCCGTTPNHIEAMARALQDRTPVTEKTVKRRAVPVS
VQSDIPSSATPLPELVRARRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLA
TPRISNAAVAAIIKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVER
MEKKIQCGAHYFLTQPVYSEEKIMAVHEATKHLNAPIYIGIMPLVSARNAEFLHHEVPGI
TLSDDIRARMAACGDDPVRAAREGIAIAKALIDAAFDLFHGIYFITPFLRYDMTVELVRY
IHEKEAAAKERKVVHG
>A0A844QDE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor arenosus|TrEMBL
MSTHRPVQPDENPAGIDLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPHEVYE
RAAIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYATILQISCRDRNRIAIQGDVLG
AAAMGVGNILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDKAKFLSGRKLSTPPA
VFLGAAINPFAPPHDFRAHRLAKKVAAGAQFVQGQYCYDVPMFRDYMQKVRDLGLLEDVF
VLCGVGPLASARTARWMRANVPGVHIPDHVIARLEGAADQKAEGKRLCIDIINEVKDIPG
VSGVHVMAYRQEEYVAEIVHESGVLKGRTPWKREARADDVMVAERLEHILHDESSETPQQ
IVKEAAN
>A0A2E8UFS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MQETSVXVTPAGARAVKNFSTILKPKMTVYVTFLPGSDFRDTLETVCRLXNEGYCPIPHF
AARSIESEKIFEXSLAKLRQEANVNEALLIGGGVDIPVGPFTASIEILRTGLFDKYGFNR
IGVAGHPEGSPDITPKECEQAIREKNEFNQHTDAXLYLATQFXFEAKPLFQWEKTIRDQG
XKLPIHVGIPGLATIQTLXRHAKQCGVGPSVRFLKKNPVDMLKMSLRNTPFSSLVKAPSS
NPSKLIFDIVTGIASDKDCLIEKCHLYPLGGLQKSVDWLYQIQDGNFSVSWDDFNVH
>A0A060SMI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pycnoporus cinnabarinus|TrEMBL
MKFVDKIVKYDKRRLFYTFEFFPPKTDQGFENLVARIGRMVGLNPLAISVTWGAGGSTKE
RSLDLAGLTQLEYGVDTILHLTCTNMVQGSVDTALREAKERGIENILALRGDPPRGKEHW
EPTDPRFQHGADLVRYIKATPEFAHFCVGVAAYPDGHPDRDTDEDGELQFLKEKVDAGAD
FIVTQLFYDVDNFLRWYGRVRAKGITVPIIPGIMPIQTYASFLRMTKLCATRVPPSLMHD
LMPIRHDDQKVKDYGVKLAVDMIRQMQRGGIEGVHFCTLNLERSVTRVLESLGLAGNIPT
LVNRLIADIPAPPERTITPHSAADQATKELIYAPKPEPDAGKGEINSAVDWDDFPNGRFG
DFKSPAYGDTDRWGSSVLQSNVAPSQWGNPRTLEDLTAMFLRYLHSKIPTTPFSPTPLSP
ESLLIFPHLERLTRRGWWTVGSQPAVNGVPSTDDVVGWGPKGGYVYQKCFVEFFVEHEDV
ERVAKKVREEGNGWINYFAANAKGDFLTNVPEGGRNAVTWGVFPGQEIAQTTIIEKESFL
SWKDEAFSIWSEWSTYYPPGSQERTLLEGVRDRRWLMTLVHHDYMDSSALWNFVFKDPNP
LV
>A0A2I2DRR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium FS1-H7996/R|TrEMBL
MLENKINNRKSGVLLYGLTPPKLNTEEHKIKAIADKQIERISVLEIDGLVLYDIQDESSR
NDKPRPFPFMDTLSPEIYNTTYLRELNLPKIIYKSVGKYSVNELNAWINEYAKNIDYSVF
VGTPSNRLKSNLSLNEAYHINKNSVNSIRLGGVIIPERHYKKNDEHIRLFNKIDKGCHFF
ISQCVYNIDNTKNFLSDYYYSSLDNNRELHTIIFTLTPCGSLKTMEFMEWLGIDIPKWLK
NDLKHSKDILLKSIEICKTIAEELLNYCKDKNIPIGFNIESVSIRKAEIDASIELLKEVK
VLMNKYQYSAIVCE
>A0A317ZM22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coraliomargarita sinensis|TrEMBL
MTPHLTPDRQLSKEPIFSIEFFPPKSENAAQQLLATAKELQSYRPDFASITYGAGGSTRS
RTLKYAKCLHEDFGFKVMPHLTCVGHSRDELREIIREFKDSGLNQIMALRGDPPQGETDF
KPHPDGLSYANELVRLIREVHPDCSIGVAGYPEKHPEAVSSDVDLLNLKRKVDAGSDFIT
TQLFFDNRIYFDFVERCQHAGIQIPILPGLLCITSGDQVRRFCALCETDIPAELEAQLAD
AGDDKQKVEALGAEWILRQARELLEKGAPGIHLYILNKSGPAVTVLNGLKKAGFYKA
>A0A6J4YI54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis Delta 1 endosymbiont|TrEMBL
MIVGDLKPLAEIVSAVKEYKQVLVLGCGSCVTVCLSGGEKEAEELSRELSQIKHWEGVPP
NFEVGCILRQCEQDLVVDYHKIPEGTDAILSLACGCGVQTLGDAFDPLPVIPALNTTFYG
ASAKPGVWAEMCRGCGDCVLTFTGGLCPVARCAKGLFNGPCGGSHNGSCEVGLDTPCVWA
MIYFRLKRQNKLHLLEEIRAPKDWRPGGAGGPRKRVRKGLGEGIK
>A0A2V2BBS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea allii|TrEMBL
MSFFHANQREALNQSLAELNGRINVSFEFFPPRTSEMEERLWNSIHRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDASRDELRGIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYGSDLVSLLKDVGEFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPTLAA
>A0A414CCH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM33-4BH|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKERGADGLHLYTMNRPAIAATIMERLG
>R7LZG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidaminococcus sp. CAG:542|TrEMBL
MKIIDLLKSPKVCVSCELFPPKKGSELEHAQEIVRTIAIQGVDYMSVTYGAGGTAVGKSV
ALVSEIERCGVPALAHLTCVGADEQKIEGVLDQLKAANVQNVLALRGDLPQGQEHPLGDY
AHASDLVKKIKSYGDFCVGGATYPEGHPEAAGLDDDLEHTKMKVEAGCDFLVTQMFFDNS
MFYNFMYRMLAKGINVPVVAGIMPVTNLKQIEKIFTLSGTPVPAPLRAMAERFADHPAAL
KQAGMAYAIGQIVDLIANGFTNIHIYTMNKPDIIGGIRSNLSEIIRC
>A0A1G9KCX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas muralis|TrEMBL
MSANEHPLGISFEFFPPNTDTGREKLMLARDALAERKPRFFSVTYGAGGSTQERTYTTVK
RVRESGINTAPHLSCVGSDKGALRELLASYRENDIDSLVALRGDLPSGMGGIGELRYANE
LVEFIRAETGDHFEIAVAAYPEAHPQAPSFEKDLENFVRKVRAGANLAITQYFFNPEAYF
HFVERARALGVETPIVPGIMPITNYTKLARFSDACGADIPRWVRKQLEAYGDDSASIAAF
GEEVVSDLCQRLLDGGAPGLHFYTLNQSAPTLRVLDNLT
>A0A2E2Q5V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp|TrEMBL
MSIGRGRSLKELIEAGEQSFSFEFFPPKDEAGEEQLWSAVRALEPYHPTFVSVTYGAGGS
SRGTTVRVTRRIAQETSMLPMAHLTCVGHTRAELEEILDEYAAAGVHHVMALRGDPEGGP
RAEWTPTEGGLTYASELVEMVAAREDFRVGVAAFPEKHPSSPSLDHDADVLVAKARAGAE
FAVTQMFFRAEDYVGLVERVRARGVDLPILPGIMPILNLAAIRRQGELIGTEVPAEVVER
IAAHDGDPVSMRAEGIALAAELCRDLLDAGAPGLHFYTLNRSKATLEIFEKLDVRP
>A0A2G1Y4V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccus sp|TrEMBL
MNDRHLSFEFFPPKTPEGREKLRLVHSQLARFNPEFFSVTYGAGGSTRDHTRDIVLEINR
AGSNASPHLSFGGDSKQSVLSLLETYREAGIRRIVALRGDLPSGMGGSTQLVYANELVQF
IREHFGDTFELLVAAYPEIHPEAESYQKDIYWLGQKFSAGASRGITQYFYNIDAYFYFRD
QCLAAGIQKPIIPGIMPITNYQNLIRFSDNCGADVPRWIRQQLKSYGTDTASIRAFGLDV
VSRLCEKLLAGGAPGLHFYTMNQADTCTVLCRNLGFPLADA
>U7NTL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. EVN1|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTREEIGELLDVYKENGINRIVALRGDMPSGMGASGELRYAN
ELVEFIRQHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEQMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCQKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A3R6VAR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM07-10AC|TrEMBL
MKISDIYSEKKSLSFEIFPPKKTEDLENIDETLAVLCECDPDFISVTFGAGGSSNCNRTI
ELAKKIKNQYHVEPVVHLTCLHYDKKEIDEFARVLTEEGIQNVLALRGDRNPDIPEKEDF
KHASDLIRYLKPKEDFCLLGACYPECHPESENKIREMRHLREKVDAGAEVLLSQLFFDNE
QFFKFVEDCRIAGIQVPIIPGIMPVINARQIKRMVTMCGASFPERFQRIIHKYEDNKEAL
FDAGMSYALSQIIDLLVSDIDGIHLYTMNNPLVARRICDGIRNII
>A0A7C1KA53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTTTPTHASAAERLRQAFAAGRFVITAELECPRDASVAHVERQARGYAPYVDAVNCTDNA
AAVVRMSPVAAAAIVARTGLTPLVQLTCRDRNRIALQSDILGAAAVGAAGIVCMTGDPPG
TGNHPDAKAVFDITSIDLMRVVRGLREGHFMSGDPVSRPPDLLVGGVENPAEGERSVSRL
AAKVEAGLELVQTQLVFDVEPFARWMEQVRAAGLHERVYILAGIAPLRRPSIARYLREHV
PGVSVPDATIERLERADDPAAEGVQVAAEVLRTVREIPGVRGAHVMSFGWIDGVRRLVDA
L
>A0A535E9H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGSSMNRMAELLARGPVLFDGAMGTELLARGVAPGRCLEELNLAEPVLVSGLHRDYIAAG
ADVIETNTFNASRFGLGEHYLEHLVREVNLAGARLAVEARNASGRPVLVAGSVGPLGRPI
EPVGSIKRSSAQRMFRERIEALVEGGVDLLVFETFSALGELELAVGVARDVAPDLPVVAS
LSFEDESNPEDAAEAAVAALAPLGVTAIGANCGSGPQPVRRVARHLAQQGAPAVAAWPNA
GLPQRVGGRLVYTSGPEYFAESAVRMVEDGVAILGGCCGTGPAHIAALRARLAEARSGVI
EVRRRQPREDEAAQTPVPTSRLARELSQRRFAISVELTPPRGIDPGRMLAGAHLLKEAGV
DYANVTDSAMARMRMGVIACAALVQQQVGLETIAHFTCRDRNVMAIQSELIGAHALGIRN
IIALRGDPPRVGDNPTATAVWDVNAVGLITIIANLNRGLDANGTPIGDKAGFHVGAAVNP
GADDLERELRLLRRKIAAGADFVVTNPIYDATALERLRDIAAEVRVPMLVGVLPLRSVRQ
AEYLHNEVPGITVPQDLRDRLERAGDGAEHLGVDLAVDFLEAARTQVQGAYVIPSLGRYD
LAARVVTRTRELVG
>A0A3A0B0A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTNPFLARLASGALLCDGAMGTLLHQRGVSIDSCFDAMNLNGRESVVQIHRDYIAAGADI
IETNTFGANRYKLAAHGLADRVRDINFRGAKHASEAREVAGMPVFLAGSVGPTGRFVAPF
GLVDPEGVRAAFREQIGALLEGGVDLLVIETMGSIDEMTAAVLAARDVSDLPIVAQMTFA
DDGRTVGGNSPQQVADALLDLGVDVIGVNCSVGPRRVLEVLHELSALLPEGTYLSGQPNA
GWPMQVGDRMIYPSTAEYFGSFVRNALDLQVRILGGCCGTTPQHTAAMRSALDEQRPPAQ
RRVAPGQQPSRHIELLPPEAPTRLAQVLGREFVVSVELDPPRGLNPAKMLAGARLLKDAG
VEFVNIADSPMARVRMSALALCFLIQTEVGLETILHFTTRDRNLMGLQSDLLGAHALGVR
NIIALTGDPPSLGDYPNATAVYDIDSTGLARVLASMNEGADASGAPIGMRASFTVAVAAD
PTRDDLEHEANRLHRKLAAGAHFVMTQPVYDMATWQRFVDVYERLHGPIGVPVVLGILPL
QSHRHAEFLHNEVPGIRLTERARERMRLAGNQGRKEGVAMAQDLLLEAREQVHGVYIMPS
FHRYEVAIEVLEAVPDRSLAAALSR
>A0A535GU99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNEGHDAASSSIGAQASFHIGMALNLNMTEQETEQEIDKYRRKIEAGAHFIMTQPIYELA
RLERFLARAGKPPIPMLLGCIPLHSSRHAEFLHNEVPGITIPDDVRSRMRAAGDQGHEEG
LKLSQELLTSARSMIEGVYLMPSYGRYDVVSKLTKMLQMQQTP
>A0A535RQ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGEVIRMPTHSRFIERLRRGPILCDGGMGTEPYAPGGSYERCFEQLNLTDAELVKTIHIE
YAAAGAEIIETNTFGANRYRLAEHGLEHNVRALNRAGAKVAREARELSERSIFLAGSIGP
LGAPLAPLGSIQASDARVAFREQAEALLETGVDLLILETISDLAEMREALAAVRSITTVP
IIACMTFSEDGTVISGEEPATVARVMRELGADVVGVNCALGPASTLEVVEAMRRGFTDAQ
LLAAQPNAGLPKRIGNRFMYMSTPEYFAEYTHRFLHAGVRLLGGCCGTTPQHIAAMSKAL
REFAPHLNAQATPAQAPQARVIVSEMEPEIAERGAAPQRSTHLAHLLAEGRFVVSAEMLP
PRSVKFTQFLQNAEYLRDRGVDVINIPDNAMARVRMSNISAARLIQQHAGVETIVHFTPR
DRNLMALQSELIGAHASDIRNILAVTGDPPTQGDFPNATGIWDVDSIGLIAILRNLNRGL
DGTGRNLGTSSSFFIGCAATPSAPDVELDLERLHRKIDAGAQYIMTQPVYAAASFLDYFE
RYRRRYGPLPIPILVGLQPLHSAQQAERFHNEVPGIVIPEDVRTRLRQAGEAATLVGLEI
LKEVFDALYPSVQGTYIMTLGRYDLVGELLPYIRSRVQ
>A0A6L7PD48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
RLFVMPNAGLPRITGGRPFYPSSPEYFADFALRAKDLGAAIIGGCCGTTPAHTRAMRAAL
DSAERMPATVEVLSRGPVLAVSDTRGGVDITATPPAEEPPEPDEPSRLRDKLAAGQYVVS
GEIEPPRGINPRKAVEGARLLREAGADAINIGDSPMARVRMSALALALRIEREVGIETII
HQTTRDRNLMALQSDLLGAHSLGIRNLIALTGDPLPEASQSSAVWDVDAIGFVRILKRLN
EGVDFAGNSLGRPTDFFVACAANPTADDIDIELRRVRAKLDEGGDMLMTQPVYDLATLTG
FFERLGPVDVPVLLGILPLMSSRHTEFIHNELAGVVVPDDVRRRMREAGDAGAAAGLEIA
FEQIEETRDFEWVSGIYIMPSFGRYEVAAELIERVRATTPVRAG
>A0A2W6C9S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MINTFLQRLARGPLLADGAMGTTLYARGVSYEHCFEELNVSQPDLVQEIHRTYIAAGAEL
IETNTFGGNRYRLAQHGLEGEVRRFNRRAASIAREAREVSGKPVFVAGSVGPLGQQLAPI
GKLKLTNVSYAFREQIDALLEGGVDLILIETMTDLAFARAAVQAARAACDLPVVAMMTFG
EDGLTVDGHAPAPVAQALRDVGADVVGANCSVGPQGVLNVIAEMHRSDGGLLAAMPNAGM
PTHYDGRTFYIATPEYFAHMTPAFINAGVTLLGGCCGTTPAHISAMRAALPTVEEAPVRP
TTTPILILDSPAPEQQLAPDQPPTGLAAKLAAGQFVVSVEMTPPRGLNPAKMLQGAEMLC
AEGADVLNMPDNAAARMRMNCISAALLIQQRVGLEVIIHFTPRDRNLLALQSDLLGAHAH
GIRNILAITGDPLHNGSYAGAAGIWEVDSIGVVAILKKMNEGLDWAGNSIGEAARFFIGV
GANPTAEDLPREIERLHQKLEAGAQFIMTQPVYDPTVLRNFLDTVGPLKIPILLGVMPLQ
SYRQAEFVHNELPGVVVPEQVRERMRAAGEKGMAEGIAMAQEFVRASWGWGQGIYLMPSF
GRYEVAGEIMRTIKEQLAANSEPLLMA
>A0A3M1ZV11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRREEFRKLVAERPLLLDGAMGTLIHAHGVPIDHCFDAVNVENPAIIAQIHRGYIDAGAD
IIETNSFGANRFKLAEYGLQDKVRVFNQAAVTIARRVIAGSFQQVWLAGSVGPLGVRLAP
LGRVSVEEAHAAFAEQIEALVTAEPRGVDLLILETMSDLKEMETAVSAARSVAPDIPLIA
NMTFARDDRTLLGFTPDRVAARLSQLDVDAIGINCSGGPAQVLRLILIMRQIAPDMTLAV
APNAGWPEQTQGGRVLYPATPEYFGKYARAFLEAGARLVGGCCGTTAEHIAMMRQALDTP
GPSELPLPEVRIVTKEETMTAVTDQPTQLADYLARKQFVVTVEMSPPRGIATQRMLAGAQ
MLKEAGANFLNVADSPLARMHMSAWAVAYLIQKEVGLETILHFPTRGRNLLRVQGDLLAA
HAMGIRNLFVVMGDPTRIGDFPEAMDSYDIVPTGLIQLIKEQFNKGMDKAGHSIDQPTNF
VVGCALNLTPSDVEREMKLLRKKIRNGADFALTQPVFDPQAARAFIQAYEDRYEEPILPL
VVGIKPLYNSRNAEFLHNEVPGMIIPEPLRERMRQAQNPQQEGVRIAQEILGELRPFVHG
VYMMPAFGRYDLVADVLDILPEL
>A0A7C1PIJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTAVPTALAAARAAGRLVVACDVSPPRGPGLADLTRFRALTRADFLCCAYLPGRAVRLEA
AVMAFLLKRELGVDAIVNLATRDMNRLALSAHLLGIAALGLENVVVLRGDDFPDRDAGRV
RAVHDTTPSELIALIARLGEGRDFRDTALMAPVSLCPGATMDFSRDFTREVRLAARKARA
GARFFLTQSIYDDTLPERFAAAYRAATGADLVAPVLWGVPVLAPGSLAFGAVPDAWRRDL
GAGRPGAEIALEFIHALRARGVEAIYLIAPILRGGERDYAAAGAVLAAL
>A0A6J2TZZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila lebanonensis|TrEMBL
MHTIEVPALNGLGQPISDIPAGPASYQPQVIFAPNQTAPSQARIGSLVADLTARGQFFYG
IEITARTAGKPTHLDFNDFLPVLPTFVSLVWLGWEYWKVHPIEHVNTLTLAKHLEPHIPV
MPHLSAYRLSEKRLDAFLAMNLSNMLAVRGDKVYADQIYTYSQQLVKRARRARGDTLSIG
VGGYPEGYTNEPTHTHYAAQSIEHLREKVESGADFIITQFCYRPEMIVQFVRDCRAANIT
VPIMMGVAVPDSYRSYGTLEKITGVRLPLELRAQVEQLKETPAAVSKFFEDLALQIIQHV
LNANVGVYGVQFFTMSRFKPVLAVLQQLRELGILQVPPASPETTNLI
>A0A3A0BFK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNPFLQRLREQPLLCDGAMGTMLYARGASSEQCLEQLVIDRPGWVTGIHQAYASAGADMI
TSHTFGANRFRLAQHGLEDKVRELNFKAVRLVRDVREVTGRALFIAGNVGPVGRRVAWDN
VAERDAVAAAFREQIEVLWEAGADLLLFETFSDLKELETAVQMAKALCDLPIVASTTYAG
DGLTLAGQSADEVTARLLTAGVDVVGVNCSVGPAPMLETLRIMHAVAPDAPLSAMPNAGF
PRRVEGRLYYPSSPEYFAEQVTPFLGLGAQIVGGCCGTTPMHIRAMRLALDAHLAARPGR
PVAAVKVAGEDELPEMYVGLSAELDGDDSARPTGLLRKLRAGKFVISVEVDPPRAFTAEK
QIEGARHAKSMGADVINVADSPMARVRMGALALCTQIQQQVDIETILHFTTRDRSLMALQ
ADLIGAHALGVRNILALTGDPPSLGDMRDSSAVYDVDSIGLVRIIHTFNQGLDIAGREMG
QKAGFTIAVACDPTRPDLGQEVDRFHQKVSGGAHYTMTQPIYDPQLWRDFLALYEERYGE
FPVPVLIGVLPLQGHRHASFLHHEVPGITLTEATLERMRLAGSQGRQEGVKMAQELLLEL
KELPHVQGVYLMPSFGRYELACQVLEVLTPEERGAVATG
>A0A7C2K985|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MIRPVRPSKTAPFAAWLELSRPRLADGAMGTMLHARGVPMGTCFDELNRSQPDLVRAIHR
EYRLAGAALLETNTFGANPYKLAAHGLEDDLEAIVAAAVALARQAAEGDPDVRIGGSIGP
LGVRLAPYGRVRPEQAAAAYRRQIDALAEAGVDLLVFETHTDLRELVLAVETARAACDLP
ILASMTYTRDDRSLLGDTPAAVARALGQAGADVVGANCSGGPAQMLRLAEQMRSATDAPL
ALMPNAGWPERHGGRIMYAATPEYLGEFARQFAAMGAAIVGGCCGTTPDHIAAMRRALDA
TETRAPATIAVVEPVPPSAAPAGEPPTRLAQRLARGEFVISVEVDPPRGFSTHRLLAAAQ
VLAEAGADTLNVADSPMARMRMSPWAVCHLIQHELGLESVLHFPTRGRNLLRIQGDLLAS
HALGVRNLFVVMGDPTAIGDYPEAMDDYDVAPSGLIRLIKQNFNAGVDQAGADIGGETSF
VVGCALNLGAPDLGRECRVLRRKVEAGADYILTQPVYDAAVVRDFRERYSRLYGELDVPL
LVGVLPLHGDRHAAFLDNEVPGIRIPDDVRRRIAEAGADAPQVGVHLAQELVESLAGLAQ
GIYLMPAFHHYDLAAEVIEHVRARVPAG
>A0A7C3JCK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPIFTPGRRWQPPYSPFKKEPFGRRVLAAVERAVKGPLFGCRMCGNCLLQETAFICPMEC
SKGVRNGPCGGSTEEYCYVDESRPCIWYRIYDRAFKMGREEMLLEVLPPLDWDKVGTETW
GDVVRQVRRVGTKKFFSGLLSKDPLQRTMVWDAVFRPVRQPDWWQGDAEYHPPAYTEPVS
ELERRLKAGEFVVTAEVAPPLTTATKKLIENIQMVKPYVAAINFTDNPSATPRMSSWACS
TLAIQQGAEPVMQIAARDRTRTGLQSEVLGANALGVRNLLCLSGDSMKLGPDPRGRMDIV
DIDSIQMLWILRRMRDENKYLDGRNIKFPPKFFLGAAASPFASEPRFQALREHKKVNAGA
QFFQTNLVFDPDGLEIWLNELAKRNILDKVYILIGITPLKNLKMAQYMHHEVPGISIPEK
IMKRMEAAGDKAEEEGVQIALELIEAVKTKQGVNGIHLMAVGWEEIVPRIVTEAGLLPKD
FVSVQAHKSAAAQPTAR
>A0A6L9ITY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRLVDLWKTKRPTLSFELFPARSDKAAVSLEQAIDALAALDPDFVSVTFGAGGSTREGSH
QLLKKLKHEKGLEVLAYFAGYGLGPDDIVAVLDSYQALGVESVLAVRGDPPREEFKPHPD
SLPYAADLVAFIRERYSFCVGVAGYPEGHIDAPSPAQDLDYLKHKLDRGAEYVITNYCYD
NRFFFDFRERCRRAGIDVPILPGVMPIYSVKMMETLAKLCGATITDEIRQGIAALDADDK
PGLVAFGIDQAVRQCTELLQADVPGIHIYTMDRSTSAVEIVNRLHTAGLM
>A0A7C3GLH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPTPRERFLNLLENADKPILLDGAMGTLLHEHGIGFDACFDALNLTNPALIADIHRRYID
AGAQIILTNTFGANRYRLAEHGLEDKVAEINRAGVELARRVVLASFKDVLVGGDVGPLGV
RLAPFGRVQPEEAREAFREQIAALAEGGVDFVVIETMSDLYEVREAVAAAREVAPDLPVV
ASLSFTRDDVTLLGDPPEKVAEALLSYGVDVLGANCSGGPAQLLRILRRMRKVAPDAYFW
IKPNAGWPERLPNGRIAYPAGAAYFGEYARFFAQEGASLVGGCCGTRPEHIAAMHQNLAE
LPPVLSLEWNPAQPQEDAAPEAAALSPSGLAQKLAAGEFVVAVEVQPPRGFSAHKVIAAA
QLLADVGADVLDVADSPMARMRMSPWAVCHLIQREVGIETTLHFPTRGRNLLRVQGDLLA
AHALGIRNVFVVMGDPTSIGDYPEAADNYDLVPSGLIKLIKQKFNAGVDHAGSTIGQPTS
FFVGCALNLNPKNPEREFKVLRRKIRAGADFALTQPVFDPEKARRFLEAYEAEFGPLEIP
VLVGVMPLYSRRHAAFLHNEVPGIEIPPEVMRRIEQAGDKAPREGVRIAQELVEAIRPWA
AGIYIMPQFRRYELAAEIVEAAKGGEASRPA
>A0A535IX23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPHRSNSGWPTLLHPPDAPTVPSPRGGGDNFGPSTLLLRSVAQASKNPASRVPPFLERLA
RGPLLGDGAMGTQLHARGVSFERSFDELNLTEPKIVEEIHRAYISAGAELIETNTFGANR
IKLARHGLDKRVRDINFRAVKLAREAREIAGEPVFIAGSVGPIGQQLGPIGRITVAQATA
AFEEQIAALLEGGADLLVLETFTNLPEILAAVSAARKTTDLPIVAQMTFAEDGLTLSAEE
PSQVVQALERAGVDVIGVNCGVGPQVALQVLEQMQQQTRLPLSGQPNAGLPARVEGRFFY
FATPEYFATFARQAADLGVAYIGGCCGTTPAHIAAMRAAPKPAASPTRITMPAPSAAIAI
DLNPAEQLPPTSFAQRLNDHAFVVSVEIDPPRGLNPAKCIAGAQLVKDAGADAVNIGDSP
MARVRMSALSLAVMIQQQVGTDTLIHFTSRDKNLMALQAELIGAHALGIRNIIALTGDPP
RIGDYPSATGVWDVDSIGLIKILQRLNEGYDWLGTSIGKPANFTIACAVNPSAEDLDHEI
DRFRQKIEAGAHLAMSQPLYDRQTLEKFFERTGPLPIPFLLGVLPLQSSRHAEFMHNEVP
GIVIPAQLRERMRLAGENGIAEGLAQSRELLHEVKGVVQGVYLMPSFGRYEVVAELVRWL
RRERVTSPS
>A0A6N8Z4L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAKVTDRISAVTGRPAFICDYSPPRSGRAQDLPAPPDNADFVSVAYNPGRAVRVNSVAMA
AALRDQRDVAPIFTLATRDMNRLALESLLLGAQALGLQNVIVVAGDPFGPRDVAMPVNDY
RATELIAAIANLNQGIDHRERPLRGATDFCIGATVDLGRGIEREARLAVRKVDVGAHFLI
TQPVFDPDDVGRFADSCARASGEELTVPVFYGVGLMETDGVSFASVPQWVTDDLANGRSG
VDIALQVWSALRPAGVGDCYVVPPIRRSGARNYAAAREFIQRAAME
>A0A6N7GG37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonosporaceae bacterium|TrEMBL
MAATPPAGSGSGRHPSIGDLIRNHPPTFSFEFFPPKTPEMETILWRSIRDLETLQPTFVS
ITYGAGGSTRDTTVEVTERVATDTTLLPMAHLTAVNHSVAELRNVIGRLAAAGIRNLMLI
RGDPPGDPEGEWVQHPEGLLYAEDLVRLARQIGDFSIGVAAFPYKHPRSLDIAGDTEKFV
QKCRAGADFAVTQMFFDDADYLRLRDRVAAAGCATPIIAGVMPVTSMKTIEMSEKFSGAP
FPPKLLPRYERVAHDPKAVRALGIARATEMCRRLLDEGVPGIHFITLNRSTATREVWESL
GVGVSA
>A0A7C3DUA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MQLIRDLYAAAPGRPLISFEFFTPKTAEGERAFFEKTLPALARLRPGYCSVTYGAGGSTR
EKTLDVVQRIQDEHGIPAMAHLTCVGSTRTQIQALLEDARRRGIRNILALRGDPPAGTGV
FEQVDGGFRYAHELVTLTRHLGGFSIGVAGFPEGHLECREGKFVDWQRLRAKIDCGADFV
LTQLFFDNAFFYEMREYLTRCLGVRVPIVPGMIAIQSVGQIRKFVALCGATIPAALASRL
DALGDDDAATAEFGIEFATAQCADLLRQGVPGLHFYTLNKAGPVTRILENLGLAAGR
>A0A536IA99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MASPSRLASLLRDGRFVVTAELSSSNSADPEATWRRADVLRGSVDAINCTDNTGAHVHMS
SLATAHLLVERGLEPIMQLTVRDRNRLALQADLLGAAALGVRNLVLMSGDDVTAGDHPEA
RRIYDIDSMQLLEVAAAMRDRGTYLSGRKLEQAPSFFIGAVENPFAPPLEFRPLRLQKKV
RAGADFIQTQLVFDVPVFKRFMDLVGGLDLQRKVFIIPSIGIPRSARGARFMQQKVPGLH
VPESLVNRLERTAPARQAEEGIQIAIELITAVREIPGIAGVHLIGIKWEEGVVQVAERAG
LLPRPTLSPVATVGGRG
>A0A2E2ZN50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLSITELIRSSSQTVYVLDVSPPRSGNDLLFQELLDLTPDVFSVAYNPGLSVRVNSVMLA
SWLQNSTGIPTSFFLATRDMNKLALQSLLLGAQLHGLNNVTVVQGDAFSETKLQFVKGVN
DFTPTEFITAIKNMNFRKDFENKNLIYPTDFCLGATVDLSKDLENEAELLHKKIFLGSDY
IVFQPFFDFDLPEKLFDIFYKKFHSHVDLPIIWGIQMLENFSKSFSEIPSWVLDELSKGR
PSIEIAQEMIEDLKNTQKVGSVYLVPPIFENGRRNYEVANELLTLIR
>A0A3L8P0I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmoricola mangrovicus|TrEMBL
MNSIGDRLDGLLLRGRRSFSFEFSPPKDAEGEEVLWRSISELEPLRPTFVSVTYGAGGGN
RDRVVEITGRIARETSMLPMAHLTCVGHTTDELDVVLGRLQQAGVRNVLALRGDPQEGPR
ASWTSTPGGLDYASELVAFVRDHADVCIGVAAFPEGHVGATSLEQDAEVLRAKRDAGASF
AVTEMVLRASDYLGLVERARAAGVEFPIIPGIMPILNLRSMERMVELSGREMPAEVLARL
EPLKDDPAAVRAEGIAMATELCETLLAAGAPGLHFYTLNRSKATREIWASLGSLTG
>A0A535MCM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MDRAPSRLAGLLRRGQFVVTAELSAVDSADPGAVFRKVDPLRDHVDAVNCTDNTGAHVHL
SSLAAARLLIDRGVEPIMQLATRDRNRLALQADLMGAAALGVRNVLLMSGDDVSAGDHPQ
ARSIYDIDSLQLIEVARGLRDRGEYLSGRKLEAAPSFFIGAVENPFAPPLDFRPLRLGKK
VAAGAEFIQTQLVFDVPRFREFMARVRDLGLIQQVFILPSVGVARSARAARFMKDKVPGV
SVPEAIVRRLEGVPTGHQSAEGIKIATEIVAELRQIPGVAGVHVIAIKWEEGVMRVIEEA
RLLPRPSVVGIPA
>A0A2D9ZT52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVMKSVLEAINKRGRKPFLLCDFSPPKGGNADLLLESYALNPDMFMVGYAPGKSVRLNPI
FAADWIHSKTKIPSIFTVSTRDMNKSAMQSLLLGAELMGLPNVLIVKGDKFSAEDXNLQS
EVYDFTPTELISDVKAMNERRDFRGNELTYPTRFCIGAALDLSRDWEKESRLTKTKITRG
XNFIVSQPTFDPELPSKFLSFYEKTIGEKLKIPVMWGIQMVEKDTISFXNVPKWVHQDLE
XGGSSYEITIDLXKRYLEFGIDTFYLVPTIYKGGRRDYLSAQAVIEDIE
>A0A535GFE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKARLKAAPRSRPRSAVRHEHAPRRHAALHSVSIRWRCHHAMTKAAAIGGSPVAIGSRLR
RALDAGRSVITAELAVPATVAHELILERAKGLLRPQIVAMNITDGLRGRPALSPIAAAAI
LTHADLGVEPIVQVVARSRARNALIADLLGASALGVRNLLCMTGDVPESSADIQDVDVFT
LIGLARGFPAGLGTELLGTAEPFCVGAAWSPFAPDPDHEADRLARKHSAGALFVQTQPVF
DAHAFAAAIDRLPRTLADLPIIVGLAPIRSCDHARRLGAIPGIVVPDRLLALLDRASDEA
DACERYWAYLDAELDWLTRNVPHRGFHLMPIGHSKRGIRQSSSFDRLYAAVTRALDAAPP
KPADVAAPVD
>A0A2E7G444|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSKLQNDIQDKNFVVTSELNPPKGTDLSLLFNKAELLKNSITAFNITDNHTSKMSMSPIA
VANLLKEQGIEPIVQLACRDKNRTALQSDILGISALGIKNILCMTGDHSNIGDDPDAKAV
FDLNGISLLKAVSSLNRGKDLANNELKGTPNIFSGAVANPGSSNINKEIDRMKEKIEAGA
KFFQTQPVYDIRKFELFFNQTSDLNIPIIAGHIMLKSADMADRFNKNIPGVSIPENVIKE
LSVTHDRKNKSSKIAINLINELKNMCQGVHLMALGWESLIPNILKTANIKS
>A0A535E7H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MWRGRFYLSNLASLLRQGEFVVTAELNPPKSASGEVVKRRAGLLKGSVDAVNVTDSNRSI
AAMAAIPAALLVREAGVEPIVQVTGRDRNRIALQADLLGAAALGLSNFLFMSGDDPKHGN
HPDAVYVKDLDGVGLVKMAVTMRDEHKFLSGDEIRQAPEYFIGATASPFTKPMSADLERT
VQKVGSGADFLQTQPVFDLATFSQWLAELRRVGGGREAAVIAGVLILRSAEQAERFARVP
GVALSQEIVDRLKKAADAEQEGTAIAVEMVKSLRALPGVRGVHLYAIEWPEAVPLVAERA
GLLPRPKVKESNP
>A0A257W7M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium 12-47-4|TrEMBL
MVSFEVLPPLKGKGIQALYDHLDPLMEFKPSFINVTYHRSESMFKKKPDGTFEQVEIRKR
PGTVGICAAIMNRYKIDAVAHLICGGFSRQETEDALIDLNFLGIDNVLVLRGDAPKNMSF
FEPDPHGHKYAIDLLKQVMSMNRGQYLEEDLKSAVYTKFCAGVAGYPEKHFEAPNLDADL
RYLKAKVDEGAEYIVTQMFFDNKKYFDFVERCKAAGINVPIIPGLKAITSKKHLTVLPKT
FHVDIPDDLSRAISECKKDDEVTKVGVEWLIQQSKELKQNGVPVLHYYTLGKAQVVVDVV
KGVF
>A0A2E2ZMJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNIVESNFKNKLTNNEFVITMEVSPPDEFDLQSFFPKFDFLSKTTIDALNITDTARAQGR
MSPLAISSLIQNQFDIETIMHIAVRHRNLLSLHSDLMGAHALGIKNIFSVMGDKPKKDSP
FFNSTFSNLTPNSALKLMNNFNKGISISGEKLKSSANFYKGAAFNPSTQNLEKEIQNLKL
KVESGADFLLTQPFYSTKTLQNILNIIGEFPIPLIIGVLPLRSIKNAQFLQNHVPGININ
SEIMSLMESSKSPIKTGMEISSNIVNQLKGKIAGMYYIPPFNNYKSILEFTKRLELPFSF
Q
>A0A535KLZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAVFLRAPRYEIFPTDDILAVVAQYVPKEVTITVTASPRRGLPATVHLAVNLARLGYKAI
PHLSARLIRDRKELGQILEAIRDAGIRGIFVVAGDAKEPAGEFPDALSLLAALPPDHGLT
EIGVTGYPERHPFIHDDVTIQAMWDKRRYATCIVSNMSFDPDTVKGWVERVRRRGVELPI
YIGMAGLADPARLLRLSTKIGVAESARFLRGHPSWLARMFRPGGYEPGRFVSALLPDIAQ
PDRRIAGLHVFTFNEIEPTERWRREMLARLV
>A0A3D9B633|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium pennipullorum|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTHGGHASAMDLVNQINDLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAITQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A535PQS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVDHDGSLDWGEAVESAQLAGLHRELAGNVPVAGFDSPRAGTPQDRNVILPVRWPPEGVA
HGATVPYSATSRARVVIGRARSGLAAPARLLGRIGLGDETSRAGLISFLTSPRYEVLPTE
DVEAPILAHVPKDVTITVTASPRRGIDATVSLAERLAKQGYPVVPHISARLIRDQAHLRE
VLDRVVALGRGEVFIVAGDAKEPAGDFPDSVLLLEAIIAEPHGLKEIGVTGYPERHSFIE
DDLTIQAMWDKRRIATYIVSNLCFSPRVVKKWVARVRRRGVQLPIYVGLAGVADPAKLLR
VSTRIGLGDSARFLKGHTNWFMRMMQPGGYDPERFTIGLLPELAAPERNVAGLHFFTFNE
IEATERWRQETLARLIAG
>A0A3N5S3I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPGFTPGRRWQPPFYPFKREPFRYRLLEAVERMVKGPMFGCRMCGNCLLQETAFICSMEC
PKGVRNGPCGGSTPEKCYVDETRPCIWYQIYDRSFKMGRQEKLLEVLPPLDWDRVGTETW
ADVWNQVRKVGVRHFVGGMFSRDVQRRAANWDSVFRPIRQPDWWKGDSVYHAPAYSEPMS
TLERRLKAGEFVVTAEVGPPLGAITGKLTRNIEMVRPYVAAVNFTDSPSATSRMSSIACS
TLCIQNGAEPVMQIAARDRTRTSIQADTIGASALGVRNVLC
>A0A536KP29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARITDLLKTGRTFSFEFFPPRNDEEQARLTRTISDLQPLQPDFVSVTYRGGRSSRERTT
RVVIDILGSTRITPMPHLTCVAHPRFELGEIIGGFRAAGLENLLALGGDPLPDEESYQEL
AYAEELVGLARMLGFESIAVAAHPAGHPKSPDRQTDRKHLAAKLQAADFAITQFFFHVEE
WQRLVDELAALGIDKPVIPGIMPITNLASIQRMAQLSGYAVPADVIAQLEKGGDDPQAVR
RIGIELACALCSDLLEAGVPGLHFYTLNFSTATREIYSGLGLVTA
>R7MBG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:813|TrEMBL
MELKEIYDGKTFVETGLAIHVPKISFDVFHPKSGDISKLFEELRVLKKYNPSLVSLTYGA
SGSGARFSKEDMKTILGLELNLMPHFTCVCETKNAIERNIINIENLGIENILALRGDIPQ
GVNPCSLDFEHANDLVEFVHEKTTLSIGIAGYPEGHVESPSLDVDIENLKRKVDAGASAI
FTQLFFDNDKFYRYVEKVEKAGINLPIIAGIMPIRSSAQIQKMLEMTHVDIPQNLINELE
RFPQQVKKIGAEFAIHQCHNLIDNGIQALHFFTLNHSDQVSEVLDNIL
>A0A536A4H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRKTSHSRKERSFSLSALASLLGSKEFVVTAELNPPKSASASVVRRRAEALRGSVDAVNV
TDSNRGTPAMAAIPAASIVRSVGLEPIVQMTGRDRNRIALQADVLGAAALGIENFVFMSG
DDPKQGSHPDAVNVKDLDGVGLLRMAAGLRDGHFLSGDEIKQPPRMTIGATASPFTKPME
ADLTKTFEKIAAGAEFLQTQPVFDLATFSQWLVEVRRADVRAIPIIAGVLVLRSPEQAER
MAKVPGLAIGQQTLDRMKAAADAESEGIAIAVEQARALRALPGVHGVHLYAIEWPEAVGR
VVEAAALLPRPQAKVVAV
>A0A520RH82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MEFIKDIHREKIATGKPAISFEFFPPKTEKGEAQLFHAVLPELLKIQPDYCSVTYGAGGS
TRGKTLEMVSRIQKDFQLTCMSHLTCVNATREEVNQVLIEANKSGIKNILALRGDPPGGK
GDFQATEGGFTYSKDLVAFVRSEFDFSIGVAGFPEGHIACKEGREVDWDRLKEKVDSGAD
FIITQLFFDNDDFFRFRDHLVKKTGMTKPIIPGILSVLSTRQIKRFTELCGASIPESMLN
RLDDLAEDDAAATEFGIEHAVRQCEALLDAGVPGLHFYCLNKSYSTNRIVDALSRYR
>A0A3D5C013|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSPQSNLQAVLEAGEFAVTCELGPPRGPDSQGVREKVKLLRGYVDAASCTDNQGAALKMG
NWGAALLCIQAGLEPIMQLSCRDRNRLAIQADVIAASAFGVRNFMSISGDSLVLGDHPMA
KPVFDLQGIQLVRLLQRLRDDGITGAGDPINGNFPFFIGGAANPFAPPYGWRPLRLLKKA
EAGQQFALTQMIFNVDRFKEWMSYVRDEGLDERVHILAGVGPLKSARMAEFMKFKIAGME
VPDEVIGRMRAAEKPRREGVKICVELIDQVRNIKGVHGVHIMAIDWEQVVPRIVERAGLL
TPRPIPDPDFALTPNSSLAAI
>H5U022|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sputi NBRC 100414|TrEMBL
MSQASPYTGPVNSSAPVPSVVERLSAPHPGQVPFSVEFLPPKDAEGEARLWRAVRVFERL
NPAFVSLTYGAGGSTRDRTVRIAGQLATETTLVPVAHLTAVDHSIAELRSLVGAYADKGI
TNILALRGDPPGDPLGEWVKHPEGVSYAEELVDLIGELGQFHVGVASFPEGHHRAPDLDH
DTRVLVSKLRAGAEYSVTQLFFDVEFYLRLRDRVAAADAEQGAKPIIPEIMPITSLASVR
RMVELSGSVLPESVERRLIDAAGSGEQEDRAAVRAVGIDIATEMSQRLIAEGVPGLHFIS
LNFAKATCEVLDRLGVDTSDALPLVSSN
>A0A661VZB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAEERANGYKSGSNLEKILRAGHFAVTAELGPPQGADPEDILRKARILKGVADAVNITDN
QTAIVRMSSIASGVLAMSEGLEPVVQMTCRDRNRLAIQADLLGAYALGMRNLLCLTGDHQ
SFGNHPTAKNVHDLDSVQLIRMVKDMRDEGCFQCGDAIKGVVPRFFIGAAANPFGDPFEF
RPYRLAKKVAAGADFIQTQLIYDIPRFREFMKRVVDMGLHEKVYILAGVGPLKSSGAARY
MRDKVPGMIVRDEYVERMVAAIKGIPKEDKKARREAWRKTGIQICIEQIQEIREIEGVAG
IHIMAIEWEEAVRPIVEGAGLLPRPTVE
>A0A535QP74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAATAGRLKAGNRMPSPSRLADLLRDGRFVVTAELSSSNSADPEATWRRAEVLRGSVDAI
NCTDNTGAHVHMSSLAASHLLVEKGFEPIMQLTVRDRNRLALQADLLGAAALGVRNLVLM
SGDDVTAGDHPEARRIYDIDSMQLLEVAATMRDRSTYLSGRKLEQAPTFFIGAVENPFAP
PLEFRPLRLQKKVRAGADFIQTQLVFDVPLFARFMTMVADLGLIGKVFIIPSIGIPRSAR
GANFMREKVPGLHVPDEIVTRLEKTPPARQSEEGIKIAVELVNAVRAIPGVSGVHLIGIK
WEEGVVRVAEAAGLLPRPTLSPLVTAGGRG
>A0A535AQU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKARLKAAPRSRARSAVRHEHGPRRHAAPHSASIRWRCHHAMTKAAAIGGSPVAIGSRLR
RALDAGRSVITAELAVPATVAHKLILERAKGLLRPQIVAMNITDGLRGRPALSPIAAAAI
LTHADLGVEPIVQVVARSRARNALIADLLGASALGVRNLLCMTGDVPESSGDIDDVDVFT
LIELARGFPAGLGTELLGTAEPFCVGAAWSPFAPDPAHEAERLVRKHAAGAVFVQTQPMF
DAHGFAAAIDRLPVSLTELPIIIGLAPIRSCDHAQRLGAIPGIVIPDRLLALLDRASDEA
DACERYWAYLDAELDWLTRNVPHRGFHLMPIGHSKRGIRQSSSFDRLYAAATRALDAAPP
NLAEVAAPVEVSGRVFRTSAV
>A0A1H9I1P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentzea xinjiangensis|TrEMBL
MTSVVERLQGQSPKFSVEFLPPRDAEDEKVLWKAVRELEGLDPAFVSITYGAGGSRRDRT
IRATGRIAQETTLLPVAHLTAVDHSVAELRNVIGWYAAIGVRNVLALRGDPPGDPMGEWV
AHPEGLNYADELVRLVRELGDFCVGVAAFPYGHPRSADLDTDLKFLLRKLNAGADYAVAQ
LFHAPEPFLRLRDRVAAAGCSAAILPGIMPMLSPRGLAKIVELSGADLPPEIARRLEPYA
DDVAGFRATGIDIATEMCQRLLDEGVPALHFYTMNRAKATREVLGRLGLVTRS
>A0A2E2V5Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIKDILKSKRTISCEFFPPRDSDGIPGVLRTXGRIRGYNPDFVSVTYGAGGSTRAFTEE
ITSSLKRDTDLEVMAHLTCVAQTKEEVHTALVRLDELGIENVIALRGDPPAGQTDFVPSE
GGFQHATELLKHVRDNFAFGLAAACYPEGHIESVDLMTDIDYVKMKVDNGADFLVTQLFY
DNQDFFKLLDRAASVGINVPIIAGILPILNANQIRRFTSLCGSKIPDELDVQLERYSDDD
DAVRELGIEYATKQVQELWNQGTAGVHFYVLNRSYSVSKILDNLKLPEHIKTT
>A0A536NMS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIAEMLARGRPTVSFEFMAPRDENEVAMVEKTIAALAGHAPDWVSVTYRKATGKKTLEL
VTRIKRQYHIEAMAHLTCANTADETRPILNWMEREGVANVLALRGDPPGPGQAFVPADPQ
FQHGSDLVAFLRRSGYRFGIGAACSAEKHPESPDQAYEFRYMQMKVDSGADFLITQLFFD
NRFYFDLVRRAKEAGITIPIVPGLMPVPSRRSLAFMAAMTGATLPPDLARAIEEAADDDA
VRALGVRHCIEQCVELLEAGVPGVHFYTFNRARAPMEILASLRGQQLLTA
>A0A4R3KZH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Keratinibaculum paraultunense|TrEMBL
MFIRDLFSIKSPVISFEIFPPKKEYPIEVVYDTIEGLEELNPDFISVTYGAGGSSKDRTI
EIASKIKNEYKIEALAHLTCYTSTRAETESILKELKINNVNNILALRGDPPAHGFEYKKD
YEYAKDLIKHIKEFGDFSIGAACYPEGHIECDSLDKDIENLKQKVSCGVDFLITQLFFDN
EKFYNYRDKLIKKGIDIPIMAGIMPVLNKNQIKKMVYLSGSSLPKKFIRIIDKYEYQPEA
LKEAGIIYAAEQIIDLLSWGVEGIHLYTMNKPDVANRIIGGISKIRCAVTEEKECII
>A0A1Q9C047|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiodinium microadriaticum|TrEMBL
MAQQLEGHQKISDLVTQVLMHALGPLFSDFASGPSSTPERALQLTSKAKNHFGVLAGMHL
NCTNKSSEMTGNALLKCKQRGVHGHPLGTAGGFSSALDLLKFIRQNHDDYFSVSVVDSDA
KFMVRFSDVGKTVLAMIYAGRPMRCLGRLLAHPRLRGGLMGQRRVAFRVLVRSLLVPAPP
PPGTRRARRVPQPAQGRFANGPSPSGRSSRFGSLTSNAKLSLKMAIVFSTPWHCTPS
>A0A7Y3NHV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
EYFAEFAKLFVDGGASIVGGDCGTTPEHTEKMAQAILNFDAGRRQIRWTATAEIAEIPPV
PLSRRSRLGTALAEGRWVSLVELVAPLGVELAPLIEKAKALESGGVEFVNFPDGPRASAR
LSAMIAAVEVSRATRLEPVLHLACRDKNLIGLQGDLFGYHAAGLRNVLLVTGDPPKVGKY
PNVTGVFDTDSVGLTKIVRRFNGGIDMGGEALPTPTSFVHGTGVNPAFPVPEQELDRALQ
KAEAGTEFFITQPVWDADQLERFLDQLQKTGKPVFLGVWPLASYRNAVFLASEVPGVVIP
RKVLDRMERHQDKESARADGVAISREIIDRLRSRIQGIQVSPPFGNVKTALEVLKGY
>A0A519FFF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax sp|TrEMBL
DSYFYFVERVQKMGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSAS
IQAFGEEVISNMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2D7YWW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium|TrEMBL
MTTNAPISFEFFPTKTEAGHEKLLATAQTLAAAGPEFFSVTYGAGGSTRDGTRRTVLQLD
GEVKVPTAPHLSCVGDSREDLRTLINDYRANGIQRIVALRGDLPSGMGHASGELRYANEL
VEFIRAETGDHFTIEVAAYPESHPQAPNFETDLQNFIRKAHAGADSAITQYFFNADCYFH
FVDRVRQAGVDIPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDSISAFG
TEVISQLCERLLDGGAPGLHFYTLNQAEPSLAVVRNLQGDR
>A0A1H6W1N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas linyingensis|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMTVARQLAGYNPDFFSCTYGAGGSTRDRTLHTVLQLD
GVVKVPTAPHLSCVGDSKTELRQLLDTYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGDHFHIEVAAYPEVHPQARSFEDDVLNFVRKAQAGADSAITQYFFNADCYFY
FVERVRKLGVKIPIVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDLESIQAFG
EQVVTEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1G5E6Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoluna spongiiphila|TrEMBL
MKSGSNLEKILAAGHFAFTGELGPPRGSNVEHVKEKAQHLVGHVDSVNITDNQTAMVRMS
SWAAALLVNEMGLEPNYQMVCRDRNRLAIQADVLGASAMGIRNMLCLTGDHQMFGDHPNA
KGVFDIDSIQLINTVKTMRDEGTFLSGEEIDGPPKMFIGAAANPFADPFEWRVHRLAKKV
EAGVDFVQTQCVYNMDKMREWVKQAVDMGLTEKVHILAGITPMKSVGMAKYMKNKVPGIE
VPDDVIKRLQGAGKGKVAEEGIKIACEQIEEFKEMKGVNGVHLMAIEWEHRVPEIAERAG
VLPRPVVE
>A0A4T0X294|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] inconspicua|TrEMBL
MSLKIVDKIRALEKDEPFFSLEFFPPKTETGMRNLYARLGRMSLLGPLFVTITWGAGGTT
ADKTIDLAVTCQKDLGLTTCMHLTCTNTSKEVIDEALQRAKDAGIKNILALRGDPARETS
VSHGIGEFQHAVDLVRYIRQEYDDYFCIGVAGYPEGHADGSFEELHQDPKKDIAYLIEKV
QAGADFIITQLFYDADKFVDYEKLVRSQPELENIEIIPGLLPINGYNIFQRASKLSHASV
PAKLLNKFPEEIQNDDDTVKDIGVDALVDIINQIYEKTDHRIKGTHFYSLNLEKSIAQIV
NKSPLLAKVVAKKELELAIEENTSSSDDEIDETITTAKRAAYANRFNTTNKVISDVKAVH
NVKMANTSSSQLQKLISISAGHGILGKDATWDDFPNGRFGDSRSPAYGEIDGYGPSLKVT
SNEAYELWGYPKSMKDISKIFINYLLKKLDCLPWSELSLSPETALIQEELISLNEKNYFT
VASQPAVNCALSKDKIVGWGPSNGFIYQKAFVEMFVSKEEWHNKLLPKLDSYGSSISYYY
GDFKGSFHTNLPKNASNCVTWGVFPNREIVQTTIIEEESFKAWTEEAFEIWKEWKLLYKK
DSDSAKLIDGILSDFYLVTIIHHEYPNESALWDLLNEN
>A0A426R0Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. Eu-32|TrEMBL
MTSDAVRGRSSDGWVTRTPSIVDRLRTSSDSRIPFSVEFSPPRDHDAEARLWRAVREFEQ
MQPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSIAELRSMVGAYADRG
ISNILVLRGDPPGDPLGDWEKHPEGVEYAEELVCLVRELGDFHVGVASFPEGHYRAVDLE
QDTRVLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAFDPEQGAKPIIPEIMPITSLRSV
RRALSLSGSALPRHIDDRFVKAAGTGSEEDRAAVREVGIELATSIGERLIAEGAPALHFI
TLNFARATREVLVNLGLSPARV
>A0A1F8M2M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_50_10|TrEMBL
MPSKFKLLLDSGKFIMTSEIGPPKGTNIEKMHHHIDILKDKVDAINVTDHQSSVMRFPSI
GGCLAIEERGGEPILQMTCRDRNRLALQAELLFAYVRGVRNVLCLTGDAVPVGDHKEAKG
VFDLDSVQLLRAIQTMESGKDLGGNDLDGNVEFCAGAIVTPEANPIEPQLIKFEKKIEAG
AEFFQTQAVYDLDKFTRFMQFARRFPVKVLAGIVLLSSAKMAKYMTENVPGIFVPQHLID
ELANAPKGTALNKGIEIAGRMVATLKKEAICDGVHIMAIGKEEVVPDILTAAGI
>A0A1C5LR00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKIIDKLNEDRIHISFEVFPPKTDAGFEKVKDATDKIAQLNPSYISVTYGAGGGTSKNTA
KIASHIKHELGVESLAHLTCASSTKEEVRQVIENLKQLEIENILALRGDIVPGMTFPSED
RFHYAYELVEEIKKHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITTAAQMKRSQELSGTVFPRRFLALLDRFGDYPD
AMKQAGIAYATDQIIDLLANGVKNIHVYSMNKPEVAAKIMENLSEVIKC
>A0A1C6APV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKINELLKKRPTLSFEIFPPKNNENDITSIYATIDELAKMNPDFISVTYGANGSTSKNTC
KIASTIKNKYGIESVAHLTCMNNTKDEIKEILEELKENGIENVLSLRGDYPKDGDGINHG
DFKYASELNEFIEENFPNDFCLSGGCYPETHYEAKNFEEDLLNLKKKVDAGAKYLVTQIF
YDNQYYYRLVREARKIGIHVPILAGIMPAHNPKQLKNIAKMSNCSVPFDLAAMIDRFAGN
PKAGREVGLHYATYQIIDLMTHGVDGIHIYTMNKPEIAKEILKRTEYIRDEFFKD
>A0A093YY97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-3808|TrEMBL
MHIKDMLNQGEQAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHA
QLTCEMVSVAQSVYGLETCMHLTCTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEK
WVATDEGFQYARDLVKYIRKTYGNHFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATF
IVTQMFYDVPNFLDWVRKVRAKGITIPIIPGIMPISTYASFLRRCNHMNARIPPGWIEAM
EPVKNDDAAVREIGRGLVTGMCRAILESGINHLHFYTMNLAQATRGVLEQLEMLPSEERP
LKQALPWRQSLGLGRRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGEPKSVKDIANVFLRYLNADIESLPWSEAPISNEADVIKQQLVS
LNERGLLTINSQPAVDGVKSSHPVYGWGPLNGYVYQKAYLELLVAPELIDELLDRIAKDP
EVTYYAVTKSGTLRSNAPGDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHETSSPSRNAIQRVMETFYLVNIVHNDFHQRDALFSLFDGLSVPNIDQAAEGDVAPA
ATPAATAATAPAANGDKVSPAIVSNVLPVA
>A0A4R1LZI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Albibacterium bauzanense|TrEMBL
MKITEHIKNAQGKALFSFELLPPVKGQSIKHIYDTIDPLMEFNPPFIDVTYHREDYIYKE
QPGGLLQKIAYRKRPGTVAICAAIMNRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARQTENAFYPTPGGHAYASDLLEHVVDMNQGKYLHDAIDVTDQSTFCIGVAGY
PEKHFEAPNLETDFKYLKKKVDLGANFIVTQMFFDNQKYLEFVKKCKEYDIHVPIIPGLK
PITHSRQLISLPKTFHIDIPVDLSDAVRACKSELDVKEVGIEWLISQSKELIEMGAPVLH
YYTMGNAEPTKRIAEAVF
>A0A1I5MC14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tranquillimonas alkanivorans|TrEMBL
MKVMSIMNLSHTARNGTRGQLQDRISVMPRPNVSFEFFPPQSLDASFRLWDTVRHLAPLD
PTFVSVTYGAGGTTRDLTHDAVTTIGKNYGLNVAAHLTCVEATRDETLAIAKRYAEAGVT
ELVALRGDPPKGKGPFRAHPDGFADSYELISALAETGDFHIRVGAYPDPHPDAAHDGADV
EWLKRKVDAGATSAITQFFFEAETFFRFRDACEKAGIDVPIIPGILPVENWKGVRKFAET
CGARIPAWVDEAFTKAERDDRTELLATALCSELCSELLDGGVEDLHFYTLNKPHLTRTVC
HALGVVPEAVLEKVA
>A0A1K2HBT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus chungangensis CAU 28 = DSM 22330|TrEMBL
MRITDIYREKNLQKKSVISLEVFPPKTDAGIETIYQTVSGLTHKPDYISVTYGAMGSLGR
ENKTLEIAEKIKKEYGIETMHHLTSINNHPEQITEILAEIKAKNVQNILALRGDLPKNTD
VTGCPDIYHYAHELITDIKKAGDFDIAAAIYPEGHVDSPLDVENIEHVKRKYDAGANFFI
SQLFFDNDKFLRLNDYVKNSGIEAPIAAGIMPVLQESQVARMLFFGASLPTRLIKIINKY
KDSPEDLQKAGMDYACKQIDDLLARGVDGVHIYTMNKPFVANTMMDRYL
>E1L4Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella atypica ACS-049-V-Sch6|TrEMBL
MTLREKHQKGQFTITVELDPPKSSSAQKVFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNEGIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDHGDHPFAQSV
FEVDCMGLLNIAKTLNSGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNGA
HFVQTQPIYDLEQAKRYIDKMSEFNVPIMLGLIPLKSFKMATYLHEKVPGINLTQDILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A2D9Z4Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula sp|TrEMBL
MASVAQFYTSEHKGLSFELFPPKTEQGDAALMRHMEVLMQFSPDYITCTYGAGGSTQTKT
MDVITAVKTAFDVPVASHLTCVGSTADDLRSYLEEASRKEVDFLVALRGDPPQGDSKFQA
VEGGFSYANELVEFIRAEFPQFGMAVAGYPEVHQEALSAESDLENLKRKVDAGADIVITQ
LFYDNTDYFDFCDRCETAGIEVPIVPGILPVTNLAQIQRITSLCGSKLPDQFVQRLSQKE
DDADWQFEVGVEFAAAQVKELIDQGAAGVHFYVLNKSQATLRVLEAADW
>A0A4Q1FR47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. CH25|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVGQINNLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREIGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A6N9I1Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Furfurilactobacillus rossiae|TrEMBL
MVADAEHQKLTDDGQRLTHTGEAQTEHPFLHPSVGHKSVLVEMDPPTTFKTASFYRGAER
LRDAGVDAITLADNSLAAVRVSNVAVAAKLKLEYGIHPIVHLTTRDHNLIGIQSEIMGLH
SLGIDDILAIAGDPAKAGDFPGATSVRDVNALGLIKLIKQYNTGVSPSGKDLDDRPNFCV
AAAFSPKITNGVLATRGIKRKIDCGADYLITQPVFDIARVNELADAFSQCGLQIPVFVGV
QPLMSKRNAEFLNEHVSGMSLPQSVLDRMAQAEIDGNEHEVGLQIAEEIADAICDRFDGV
HVVTPFNRYKMAAKLVTHIRQRENVAVNG
>A0A7Y2K8S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriaceae bacterium|TrEMBL
MRVIDHLMNAKEPLISFELIPPKRGGDIKDVLAVLDELIKYKPPFIDITSHSAEVIYDET
ADGIKKKIKRKRPGTLGICALIQNKYNVDAVPHILVKGFTREETEDFLIELNYLAIDNVL
AVRGDDSGYDKPVPLGKSIHEHSLSLVQQIVDMNKGNYLEENLLDAKATNFCVGVGGYPE
KHFEAPNLNSDVRYAKQKADTGADYIVTQMFYDNKHYFDYVKLCRESGIDIPIIPGLKIL
TSKSQLYSIPKNFHVSIPTDLADEVEAAKPEDVLKIGVEWSVNQVKQLLDENVPSVHFYI
MLDSKPISMLLDRLKIFKKTA
>A0A6J7GUT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSKLRDLLTQTKDVVYTAEFPIIDGGGMEQVKKNVDRLAPWFVAVNATDNTAAHAHASNV
SVAIAMKQHGLEPIMQIVCRDKNRLAIQADMAGANLHGIENIALLTGDDVTAGDEPETRR
VFDLDGPQAINVASILNAGTYLSGRKLNPAPNFFICSVENPFAPPHDYRIERALKKHRAG
AQMIQLQIGYHPDRLEKFCAGVAATVPDLAIIPSVVLIKSAKPLSFMNDKVPGISVPQEV
IDRVAQSADQSEAAYQLALEQCQHALALPGVRGLHITDFRHDDTLERLMRDLGRTPNQYT
>A0A5C6XL27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lujinxingia vulgaris|TrEMBL
MSQIQMQSPFLKALAAGPVVFDGAIGTQLYERGIYINKSFDDANLSRPDLVAAVHAEYLS
AGAEVITTNTFSSNRIKLKRHGLEERAAEIASAGARIAREVAGDLALVAGSVGPTGRTPT
MLTERELEEMREAFREQITALAEGGVDVIVLETFRQLAEVRMALEAAREVCDLPVIAQMS
FDGERRTGDGADPERVAMLLADWGADVVGANCMEGPHVLYDVVVDMLSCGLPVIAQPNAG
YPRKVDERLVYMATPEYFGVYARRFFKAGVRLVGGCCGTGPEHIRQVSAAARMLGGGRAS
VEVSAARMPREEAEPELAQSQKVPTRLAEKIEAAHRSRAAGEAVSRENFVVSVEVNPPSG
LRADRAIEAARMLIEGGVDVINIADGPRASVRMANWALGRMLQESLDIEVILHLCGRDRN
LLGLQSDVLAFEALDLRNLVVITGDPPKVGDYPHATAVFDLDSVGILRMINNFNRGVDPA
GKPVGDATAFYCACGAEPAAADYERELRRLELKKAAGARFVMTQPVYDPAVLDRFLADIA
HLDLPVLVGLLPLASARNAEFLHNEVPGMAVPLEVRERMRAAGTGQAARAEGVRIAQETL
EAVGSRVTGAYIMPPFGRYEAALEILSCLPGYAQTPATEEAR
>A0A6J7D6V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MAIFRSHDRRPDAGSAALAPVIVDRVQHAHLELIPTPKAHLQFPALPPACTVSVTCSPAK
DIQATLDMAAQLLDLGHTVIPHLAARMVEGPDHVAGIASWFNDHGVSDVFVIGGDAPEPR
GPYLDAAALIAALLDSNARLTNIGFGGYPDGHATIPLPALAEAITAKQQLLDSAGISGWV
STQMCFDTKAVTRWISQNRAAGMHLPIHLGIPGVIDTTKLLTMGAKLGIGASLRYLRKNR
AVVSKLATPGGYDPMDMLAPMARDIETLDIAALHIFTFNQVTNTAEWRRAVLDGAGPTES
NLNTGSNNDSGTSTTAGAASLTRG
>A0A6J6T7J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MMRSLKNQLTYSFEFFPPKDVEGEERLWAAMSQLESIAPDFISVTYGAGGSTRDRTIRIT
SEITARTHIPTVAHLTCVGSTRDELIEILGKYRDAGIKSILALRGDPTGGPRAPWTPTPN
GLSHADELVTLAAEFGGFTIGVAAFPDGHPASDGDSSHDIEVLIEKERRGATFATTQFFF
EVDKWKSLVDKLEAKGSSLPIIPGILPVTNVKQLNRMAELSGTPIPASVSEAFAKVEDNP
EDVRKLGVDIATKLCQELLEAGAPGLHFYTMNTSTATREIYSQIKDLR
>A0A2N2M042|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-8|TrEMBL
MDTKNKFLEKLHLSKPILSDGAMGTNLHLKGVRFDECFDDLNLTNPAIVAEVHRSYLEAG
SQMLQTNTFGANRFKLSQFGLENKVDEINRAGVDLIRRVGLASFKDVIIAGDVGPLGVRL
APFGRVQLDEARKVFKEQINALITSNVDVILIETMTDFYEVKEAILAAREVDPSVPVIAS
MTFTRDDRTLLGDSPEKVAQNIFAAGADVIGINCSGGPLQLLRILKKMKNVVPQAMFSVM
PNAGWPEQQDGRIMYPAGPEYFGDYAIAFWQAGARVLGGCCGTTYQHIASMAKVLSETKI
SDVILNIDFPLEKESNEEPEISDQSELSKKLAKGDFIVAVEMDPPRGLSTKKLLAGASLL
VDSGADVINVADSPMARMRMSPWAVCNLIQNYLQTETVLHFPTRGRNLLRVQGDLLAAHA
LGIRNVFVVMGDPTSIGDYPEASDKFDLVPSGLINLIKKSFNAGLDHAGSEIGQPTSFFV
GAALNLNALHPENEAKNLLRKIEAGADFFLTQPVFDITRTKESIKRMRDRAGDSKIRVFI
GILPLASDRHANFLHHEVPGISIPDDTMERMQKAGTDGARTGIKIAVELIQKLHDFVDGV
YLMPAFNRFDYASEIVEEIKNH
>A0A1S8SYJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium puniceum|TrEMBL
MIKEYLKNNVIISDGAMGTYYSELTGNDVSYCEFANLNDKETIKKIHTEYIDAGAKLIRT
NTFSANIYDLGVSKERLKDIINSGINIAKEATQDKSIFIGGSIGPIKEDNLDESNKDILD
EYKYIVDCFLDENIDIFIFETFSNYNYLKEISEYIKKKNQNSFILTQFAVKPDGFTRDGL
SISKLVNSVKNIKDIDAYGFNCGSGPMYISEVINNLNIGNDIVSALPNAGYPEIIHERTV
YPNNPVYFAKKIIDIKSMGASIIGGCCGTNPKYIKQIVSLIHENSKVINTTIRKEEKAKE
NERKVQNTFKNKLDNNEFVIAIELSAPINTDISKLIEGAKICKANNIDLVTVPDSPMSKV
RADSTIIAAKIKREIGIEAMPHICCRDKNTNAIRSTLIGSHVEDIRNVLAVTGDPISDAS
KIETKSVFNLNSFRLMELIEDMNVELFNEDNILIGGALNLNVLNKEVEFKRMLKKIDKGA
KFFLTQPVYDDEAIEFLKKAKERTNVKILAGLLPVVNYRNAVFLNNELPGVTIPDKYVKM
FSEDMSKEEAQEVGIKITTEIGKKIKDICDGLYFITPFNRVEMLMEIIKRIKE
>A0A679GUR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKAIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2A7VYC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKDAAIEEGIRISQELIDTAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6J6G075|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MADFAITQFFFEADPYLRLVDGLSAFGCDKPVLPGIMPVTNAAQVVRFAELAGAAFPPHL
AARFDAIADDPDAVRALGVELASELCQRLLDEGAPGLHFYTLNRSTATREIAANLGLGDA
SSTGA
>A0A1Y2R0S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp. IBVHS1|TrEMBL
MSLPISLEFFPTKTAEGAVKLRAVRQQLYALKPEFCSVTFGAGGSTQDGTLQAVSEIMAE
GCPAAPHLSCIGQSRESIRERLAAYSAAGIRRIVALRGDLPSGYGTGGEFRYASDLVAFV
RSETGDRFHIEVAAYPETHPQAKSPLSDLDAFAAKVKAGANSGITQYFFNSDAYFRYVDD
LHAMGVDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRMRLQAFGDDTASIKAFGLDVV
TDLCDQLRNAGVPGLHFYTMNQSGATSEIVRRLALA
>A0A316SBP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Succinivibrio sp|TrEMBL
MNTADLFKYKTVFSLEVFPPKRESSLQSIYSAFDNLKEIRPDYISVTYGAGGSSNINATA
NIADRLVQNYGYTAVAHLAGIGLKKADVEHIIDNLLPMGVNNILALRGDERDDLEKGDFE
HAVDLISYIKGKYGDKVNIIAACYPEGHIEAHNIVDDVKHLKEKVDAGASQLITQLFFNN
DSFYRFKERCDLVGIKVPIQAGIMPVANKKQIERIVTLCGVELPAKFTKIMSKYEDNPEA
LRDAGIAYAIDQIVDLITQGIDGIHLYTMNNPYMRVK
>A0A517DRS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa termitida|TrEMBL
MSEAVALDKQAELKTDSKLEKLYSLGHFVVTGELGPPQHAEGHELEHHAHELKDIVDGFN
LTDNQTAIVRLSSIAAGIHVLKGGGVPIIQMTCRDRNRIAMQSDLLGAYSLGIRDVLCLS
GDHQSFGNHPTSKNVYDVDSVQLIAMVKKMRDDKKFLSDAVIKANEPRFFIGAVENPFGD
PFEFRAIRLEKKVNAGADFIQTQAIFDLEKFARFMEMAVARGIHERTKITAGILPVRSVK
ALQYMKKDVAGMEIPDSLIERMKKAEDPKKEGIQVAIEMCNELKKIPGVAGIHIMPVGWE
AALPEIVKGAGFLPRPKV
>A0A1Q8JXQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. Ae707_Ps1|TrEMBL
MDLRRRIWERHGEFLLFAVTPPRRSTSPQRAQEIADATVARLRPLGLDGLVLYDIDDESD
RNVEQRPFPFVSTLDPADYLARYLTDWTAPAVIYRVVGKYPEADLRPWLDAQDPERVLSV
FVGASSRDKEVAMSLKQAHTLRAQASPELAVGGVAIPERHTRSGDEHLRLLAKQDASCSF
FVTQVVYDVNAAKNVVSDYRLECDARGVDPAPIVFTFTVVGSTKTLEFLSWLGVEVPRWI
QNDLLHSDDVLTTSYEQSLSCALDLIAFCRRLGVPFGLNIESVSSRRTEIEQAVQLAARL
GQELHRPHR
>A0A1F9BW02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_50_11|TrEMBL
MKSGSNLEKVLTKGLFAVTGELGPPKGNDVSVIKRKADLLKGYVDAVNVTDNQTAIVRMS
SIATSSLLLQTGLEPVMQMVTRDRNRIAIQSDLFGATALGIKNMLCLTGDHHTFGNQVDS
KNVHDLDSIQLIYCVRTMRDQGTLLGGEEKIEGKFNMFIGAAENPFGDPFEFRAVRLSKK
AAAGVDFIQTQCIYDMNRFKEWMKMVRDRGLHEKVHILAGVTPLKSGGMARYMAKNVSGI
IIPDEIIDRIVKAKKPAEEGIKLVVEQIQELREIEGVHGVHIMAIEWEQMVSQITEMAGL
LPRPKVE
>A0A0M3U9P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. AL041005-10|TrEMBL
MLDPPDRGTGPRRTDRRAVLARVLREATYEVLPFPSAADKVLAHVPTGTGLSVTTTEAKG
LGPTVDLAVRLTGHGYRVAPHLAARLVRDRAHLTDLTDRLTGAGVRTLFVVGGDAAEPAG
CYPDSLALLTDLHEVAGGRFDHIGIGGYPEGHGGIADELIEGALTAKAPHATQIVTQLCF
DPSATVRWARRIAAAGVRLPVRVGVPGAVSRQKLIRVSAGLGLGQSARFLRKQQGMVRRF
FTPGGYRPDRVLDGIAPALAAGDIGLAGIHVFTFNDLESTETWRRRLLERLGR
>A0A521UQU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospiraceae bacterium|TrEMBL
KAGIDVPIVPGLKPLTKAHQLTSIPRNFYVDIPEELSIEIGKASTPEARTEVGIEWCTMQ
SKELKKSGVPCLHYYTMGDATTIRKVAEAVL
>A0A6V8SDW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium fungisolvens|TrEMBL
MLIKDLFKQKRMVFSFEIFPPKLTSPIETVYNTIEELAVLNPDYISVTYGAGGSVNNNRT
CELSSLVKNKYGIEALAHLTCINSSEDKINRIVDNLNKNNIKNILALRGDVNGEENGSDR
YNYAFELIKHLREKGNLCLGAACYPEGHVQSDNLDNDILYLKNKVDAGADFLVSQLFFDN
NLYYNFLDKVASQNINVPIQAGIMPVTNKKQIERIASLSGAHLPQKFVKIMDKYEHNKEA
LRDAGIAYAVEQIVDLVSSGVSGIHLYTMNNPYVAKKITTSIESLINHINEEAI
>A0A7X5R398|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacter cavernae|TrEMBL
MRVEIIPSKDAVANIVAHLPRDTTLTVTCLPQHGLEPTLRVSTQLADLGYDVIPHLSARL
IVSEAELVAHLDRLADHGIRSLFVIGGDGPQHGGPFADGGELLCAVRENWGKLANLGIAA
YPEGHPLFNREQGIDLLLHKQSTADYAVTQLCFQAPVVAEFLRDTAAAGVTLPVWIGLPA
AVNWRRLVAIGTKIGVGASLAFARKNSALQLLSAAHFDPQVFSAEVTGALTNWANAESEI
ALPAGIHLYSFNDFRSLSTSRP
>A0A2G4F194|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tychonema bourrellyi FEM_GT703|TrEMBL
MNRFRTACSTPGEFIITAEVAPPKGGDMTHTLAMAELLKNRVHAINITDGSRAVLRMSPL
AVSVILLQHGIEPICQVACRDRNQIGLQADLMGAHALGIRNILALTGDPVKAGDHPKAKS
VFDFEAIRLLQAIQKMNTGTDWNDKPLTDGVTDLFAGAAVDPQCPSWSGLQSRFEKKVAA
GAQFFQSQLITDFELFDKFMHHIAAGCNKPILAGIFLFKSAKNAEFIRKNVPGVHIPQET
IDRLAKATEPLQEGIKIAAEQVKLARQLCQGVHMMAVKREDLIPQILDLAGIDPLS
>A0A530BT38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
SADPEDVYNRAKIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNR
IAIQGDVLGGAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGRFLS
GRKLTTPPQVFLGAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQSAR
DLGHTEKVFVLCGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDI
INEVKEIPGVAGVHVMAYRQEEYVAEIVDESGVLKGRQPWKREMRRDDQVVADRLDHLLH
DEITETQVDMVKTAH
>A0A531CQ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MTVRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQSARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A4U6QJ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nakamurella flava|TrEMBL
MVSVRERLSAPGPKFSVEFMPPRNDGEENVLWNAVRRLESLHPAFVSVTYGAGGSHRGRT
IRVTERIATETTLLPVAHLTAVGHSVAELRQVIGSYAAVGVTNILALRGDPPGDDPTAEW
VAHPEGLTYASELVRLTRSLGDFSVGVAAYPDTHPRSPDVDTDTRFLVDKVRAGADYAIT
QMLFSAADYTGLRDRMLAAGADVPVIPGIMPVTSYQRLMRIHELSGQSIPADLAEELYAV
RDDPAAGRAIGMDHAIRMSADLLSEGAPCLHFYTFNRSKATIEVLTALGLTPALRR
>A0A0P0NA22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus anginosus|TrEMBL
MSSQSPSLSFEVFPPNPAVGNEKIMAALKEMQDLVPHFISVTASNSKFNIEETTVRLADF
IRNDLHIPTIAHLPAVYLTKEMVTETLTALDKVGVHKVLALRGDILPDVEPQKDFVYATD
LIEYIKKEAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYD
FQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSSTAHQIYQATHTFFDK
>F1KZ16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ascaris suum|TrEMBL
MITTTTTNESNTTNDGMKKNDSLPVFPYSGGYMNGEQSASSLEGENLSGRNREQNGKLSM
HGGNYIPLHERIRKRINDNSPFFSLEFFPPKTANGVANFFNRLDRFREGNPMFIDITWHL
SSDPANIKKETSSLSIAAGCLNYCRMDTMLHITCAQYTKEQTLRHLQMSKAIGLRNILAL
RGDIPQQDENPIVYKYRALDMIRWIKEEYGDYFTIGCAGYPTGHPEAPSYAADLRYLKSK
VDAGAQLIITQLFFDADVFEKFVHDCREIGITVPIIPGVMPIQGYESIRRIAALSQLTIP
ESILKALEPIRHDDDAVRSFGIRHAVEMCRRLLNSGTATSIHLYTMNREASCREILQELG
LWTRMPMRSLPWKSFEGNHPLRSKEDVRPIFWSTRPKSYVFRTRDWDEFPNGRWGNSSSP
AFNDLADYYLFYLKGQLNKEEQLRMYGYQLENMEAVRKVFVNFITQQPNEHNVKVTRLPW
NEQDIGTDAETVLIRDQLIWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKGYL
EFFTCRKNADVLRNILPSYPRLSCHIINHNASIDWTNTDATTPIAVTWGVFPGCEIAQPT
VVDPLSFHVWKDEAYEAWNNWASIYPDGSKSRKILEEIHDEFCLVTLVDNDFPKPLIIFE
VLAEVLRIAGSTA
>A0A5E7KMI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAIYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A8D0AU87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sander lucioperca|TrEMBL
MVNQVQRGDGSWQSCKSDSSGASNSSESSKESSRSSTPVLDVDRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGTGGPLFIDITWHPAGDPGSDKETSSLMIASTAV
NYCGLESILHLTCCNQTKEKISGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATD
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNY
GIKQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LKMWGDELMSEESVYEVFTCYITAQPNRSGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIAGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVN
YHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKKHIVFDTRRTRPS
PCGSSSGRSSTKTSLLHG
>A0A7X9RNC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium thermophilum|TrEMBL
MHQPMFSIEVFPPKRNAPVGTIYDTLDGLQGLNPDFISVTYGTGKSSDRTATARIANTIR
KEYDIPAVAHLTAQYTTREQVDEALDMFKQAGVSAVLALRGDPVPGREPEGAFEHASDLV
AYIREHEPDMTIFGACYPECHPQATDLDEDIRNLKIKVDAGASHLISQLFYDNADFYHFL
DKARAAGIDVPIEAGIMPVTNAKQIRRMVRMCSSRVPLPLESLLDKWGDDPKTLKQAGVI
YASNQIADLVAHGVDGVHLYSMNKPAVTRQIWHNVEDLFSPAQTGTDFA
>A0A6M0J761|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. UIC 10630|TrEMBL
MYHTHSPTAFRRAVQAGEFLVTAEVAPPKGGNPAHMIQMAATLKGRVHAVNVTDGSRAVL
RMSSLLASVILSQNGIEPICQVACRDRNRIALQADLMGAHALGIRNILALTGDPVKAGDH
PDAKAVFDLEAVRLLQLIRKMNQGVDCNEKPLTDGALDLFVGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFERLEKFMDTIASGYKKPILAGIFLLKSAKNAQFINRCVPGVN
IPQHIIDRLAKAKEPFEEGIKIAAEQVQIARQLCQGVHLMAVKREDAIAPILDLAGIAPV
NQLVSK
>A0A432HK45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISDKLEDFKTQGKTYYSFEFFPPKTDFGLDNLYSRIDRMASLQPAYIDITWGAGGSTA
DRTLEMSKTIQKYFGLEVMMHLTCTNMPVSSINKVLVDVQENGLSNILALRGDPPEGNVE
WEKHEQGFKYGIDLVRFIRKEFGDDFFLGVAGYPDSHQEQSDIDLDVSYLKEKVDAGSDI
VVTQLFYDVDKFLVFRDKCSNKGIQVPIIPGIMPIHNYARFIKFTQFCKISIPNSVTKTI
ESLKNDDSSVINYGIDQATSMCEKLIAEGVPGLHFYTLNLEHSVSGILELLGLTSTQRSV
RELPWRQSTAENRKTTEDVRPIYWSNRPVSYLTRTETWDDFPNGRWGDITSPTFGELNQY
HAIRAGSKSDKVKTRRRKLWGEPKSIRDITKVFVSFCKGKINSLPWCEIPLAIESGQISK
ELVKLNESGFLTINSQPSVNGAPSEDPDVGWGTPGGKVYQKAYLEFFTTKNKLDTLLETI
DSLDNISYQAINS
>R5T7B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium hathewayi CAG:224|TrEMBL
MKIKDILGQGKPTLSFEVFPPKTEDKYESVERAAAEIAKLKPSFMSVTYGAGGGTSRYTV
DIASTLHHEYQVTALAHVTCVSSTREKVHEVLEELKAAGIENILALRGDVPKDGPVASDY
RFASELIREIRAYGDFCIGAACYPEGHVESVSKTIDMDYLKQKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVVAGIMPVTNVKQIIRSCQLSGTYLPSRFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANGVDAIHVYSMNKPDVAAKIKENLSEILS
>A0A2A5D405|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIEFLEKANKTLFSFEIIPPTRGGSIDRVFNLVEALIPFDPPFIDLTSRSAEVYYEDA
GEGKMIRFIRRKRPGTIGISAAIKNKFNVETVPHILCRGFTREETEDALIELNYLGINNV
LAVRGDELRKDAPDSPGKTRHRYASNLVSQIKDMNDGKYVEELIDAAPTNFCIGVGAYPE
KHFEAPNMATDIKYLKAKMDAGADYIVTQMFYDNSAFFKFVDDCRSAGIDVPIIPGIKIL
STEKHLSVIPKNFYVDIPEALSEKVIGQSKEDIVNIGVEWALEQVQALVDAKVPCVHFYI
MSSAKSAAKVVSQFK
>A0A101FF62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermacetogenium phaeum|TrEMBL
MKEINPEKLKAGSNLEKVLVSGQFACTGEIGPPTYASFDVIDKHAEEMRGLVDSINFTDN
QTAVVRLSSWAASVHLIQLGLEPNLQMVCRDRNRLAMQSDLLGAYALGVRNVLCLTGDHQ
AFGNHPGCKGVFDVDSVQLIHMLKRLRDDGCFECGAECKVPPKFFIGCAENPFGDPFEFR
AIRLEKKIEAGADFVQTQCILDMERFELFMEKVRERGLHKRAYICAGIMPVKSPRMARYM
QTGVPGMLVSEEFCQRLEKAEDPKAEAVEISVEYIKRCQQIEGVAGVHIMAVAWESIVPT
IVKKAGLAPRPTF
>A0A0C2A6T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVTEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A420E2D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum lutimaris|TrEMBL
MKVIEHLEKANGTSLFSFEILPPLKGDTIESIFKNIDPLMEFNPPFIDVTYHREEYVYKE
LGDGLLKKQVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPENDGHAYASELVTQIENLNKGRYLDDDLQNSSKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKNGANYVVTQMFFDNQKYFEFVEKCREEGITVPIIPGLK
PISTKKQLNLIPHRFKVDLPDALVKEVVNCKSNAEVRQVGVEWCIAQSKELQQKGVPILH
YYSMGRSTNIQQIAEAVF
>A0A397EJ72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces astaci|TrEMBL
MKIIDKINEKIEKKEPFYSFEYFPPKTPAGVTNLYTRMDRMALMEPLFCDMTWGAGGSTA
SMTIELCVNAQKLSGLEMLMHLTCTNMPKGSIKNALDSAKDAGIQNILALRGDPPRGQTE
FKECEGGFAYAIDLVKYIREEYGDYFCIAVAGYPEGHSDAKDLDTDILHLKEKVDAGADF
IVTQLFYDVQKYFDFVDKCRAVGINVPILPGIMPIQNYNGFVRMSSMCGHVPDAILQALE
PIKDNDEAVKDYGVELGIQMCRDLLDHGVPGLHMYTLNLERSTRLILEGLGLTATARREL
PWRPAMWGESPVTYADVYETFTRYVMGAVKSLPWCDTPLHLETKSIQERLAAVNRAGYLT
INSQPRVNAAPSDDPMFGWGGPGGHVYQKAYVECFVSPENLKRIIEKCNKMKHVQYHAVD
VNGNSYSNCGKGTTAVTWGSFPNKEILQPTIVDTDSFMAWKDEAFSLWLSMWASLYHDES
AAHALIHQIRDSFFLVSIVDNNFVNGDIWDAFDVDVTTASAAGP
>A0A660XPN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIEFLAKAEDPLISFEIIPPDRGRSANEIYRIVEELMIFRPPFIDVTSHAADARYVEQ
PDGSFIRKISRKRPGTIGLSAAIKYRFKVETVVHLLCTGFTREETEDALIELNYLGIENV
MALRGDVRKFKKHIQPDRTINPYAADLVGQIQNMNKGIFLEDELDADRTDFCIGVAGYPE
KHEDAPN
>A0A4Q5QGX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriaceae bacterium|TrEMBL
LSDAVQSCKNDKEVKEVGIEWMINQCKELKEMGAPVLHFYTMGNAEPTKRIAKEVF
>A0A839S273|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella isguenensis|TrEMBL
MKRRRESGKAAVPAAARAGILARPRFEVLPLSGVLEETGALPEQTVVTVTASPRCGTGAT
VELCEKLAAQHLRPVPHLAARQLTGRGELIDVLDRLAGAGVADVFVVGGDTDESAGPYPD
GESLLREMADLGRLPAEVGVPSYPEGHPSIDDATLWASLRSKQDLATYTVTQLCFDLTAI
RTFLRRAGEEGVTLPIVIGVPGAVDVATLAKVGARIGVGDSLRFVTSHRSLVGRLLRPRR
GRDAVLRGVADLAARSGETTPSGVHCYTFNKVRATARMVAELPAATRGTGGPAREPRGER
>A0A7R8AI29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus puulaauensis|TrEMBL
MHVSEKLSQNEAAGRIGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDVTWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMAQEKVDDALQAAYKAGCTNILALRGDPPREKEV
WEATDDGFRYAKDLVKYIREKYGNHFCIGVGGYPEGADDNSDVDLLIDHLKEKVDAGSTF
VVTQMFYNTENFIQWVQKCRAKGITVPIIPGIMPIQTYAAFIRRANWTKTQIPPDWLEAL
EPVKNDDAAVKQIGKRLIADMCRRLIDSGIKHLHFYTMNLAQSTQLVLEDLQLMPTAETP
IPRPLPWRPSLGLNRREEDVRPIFWRNRNSSYIARTQIWDEFPNGRWTDSRSPAFGELDA
YGVGIKGTNEQNIKLWGEPKSIRDLAEVFVRFLEGQLDRLPWSDSPITPETNAIKDPLVE
LNKGGFLTINSQPAVNGVKSSHPIYGWGPKNGFVYQKAYLELLIPAYLIDDLISRIEANE
DLTYHAVTKYGELRTNTRDSPNALTWGIFAGREVVQPTIVETVSFLAWKDEAYQLGEDWA
KCHDSASSSRKLLQSVMDSWYLVNIVNNDFHNTYDLFELFKGLNVKDIDVEFPGEISEPK
VQNGTTNGTTNGATNGTTPAQPVKN
>A0A7Y0NRN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. SG918|TrEMBL
MKITEHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QANGLLQKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHSYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMSTDFKYLKKKVEAGAEFIVTQMFFDNQKYFDFVKKCRENDINIPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNNEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKKIAKAIF
>A0A3E2ET34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adlercreutzia equolifaciens|TrEMBL
METVARIFESCREDRLSESCVARVAVAQEAGAACTEVSESRARHIPFSVEMFPPKGQLTL
DAARKVVEGLRAASPDFISVTCSAGGSGNGHGGQTVAIAELIQNEAATPAVAHFTCVSAT
ASLVATEVEALRAAGVETVLALRGDLAPGQEPADFRYAYELIPRLKAAGLCVGAAAYPEG
HIDCLDPRENIRHLRAKQDAGADFFITQLFFNNDDFYRFREAAESAGVAAPISCGIMPFL
GKSQIQRMVFLCGSSLPAPIIKLLAKYEDDPVALRQAGIEYACNQLVDLGRHGVNGLHVY
AMNQPDIACAAAEAVAAAGLR
>A0A4Q8MLF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp. JR1-6|TrEMBL
MNKATARPARKDIRLSFEFFPPKSAEAEGQLWQTAAALSAYDPGFMSVTYGAGGSTKAPT
LATVRQLLAMGLPAASHLTCVGATKEEVHAVVAEFQAVGVKHFVALRGDPPGGVGTAYQP
YPGGYANAAELTAGLRGLADFEISVSAYPEKHPQSPDVAADIDMLKRKVDAGATRALTQF
FFENDDFERYLERVRKAGISIPVVPGILPVHNLSQVQKFAGLCGASVPDWLADRLAPVDD
RPQERAAVAIDLAARQVEDLIARGIGEFHFYTMNRATLVSAVCDRVGFARSERQPAGAAA
>A0A2T2UFN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium SW_6_67_9|TrEMBL
MRFEDEPVPGFQLPILPGHSSPGRLERVLRAGRFAVTAEIAPPDSADPNEVYLRTRIFDG
YVDAINATDGSGANCHMSSTGVCSLLTREGYATIMQVSCRDKNRIAIQGDVLGAAAMGVA
NVLCLTGDGVQAGDQPEAKPVFDLDCMSLLETVRTMRDEGRLLSGRNLSATPKLFLGAAS
NPFSPPHDFRPERLAKKIAAGAQYIQTQYCFDIEMLKRFMQRVRDLGLHERVFIIVGVGP
LASANAARWIRTHVPGIHIPDEIIDRLAGAKKPKLEGRKICVELIQQIREIEGVHGVHVM
AYRQEEAVAEIIDASGVLEEREPWHPHRDADTDIGEHASVAS
>A0A1V4S3P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4484_190.2|TrEMBL
MKLKEALKKGRFVVTSEVQTPIDEDPQALIKRLELVRGRVDGVTVPELEIEGIVGDSIKM
CDLLKKNRFQSIYQTTTRDKSRPQLQKDLITAHDTGVENLLVFTEDYRITGDSLQEMMFF
HVDSGKLASVLEHMREGQTIEGKELPSKANFTLGSGVESGWGKNVPELEMKEMEEMTKIG
TGYFLTTPVFDVAHFEKFLKQVNTFGVPVIAEVMIIRTAGMAQFLNRHFKSGLVPDWMIK
KLASAPDKQKASIELFADTVKGLKDLCQGVHIITIGGEEKLRLYLDAAKLK
>A0A0Q6P5K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp. Root105|TrEMBL
MRPDVRPNFQVSFEFFPPKTDVMEERFWDSIHKLAPLHPRFVSVTYGAGGSTRERTLRMV
SRVKADTGVDAAAHLTCVGATRDEVDTVVRGYQEAGISRIVALRGDPAEGIGKPFTPHPE
GYKNAADLVAGIRRIGEFDISVAAYPEKHPQSPSWEADIDNLKRKLDAGATRAITQMFFD
NDDYFRFVERARAAGITAPIVPGIQPIHSFKQISGFAARCGASIPGWVAERFEGLEEDPE
THALVASAVAAEQVLELVDNGITEFHFYTLNRSNLVLALARLLGARPD
>B9M771|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geotalea daltonii (strain DSM 22248 / JCM 15807 / FRC-32)|TrEMBL
MISRLQQKLMTGSFVLTAEVCPPKGSDCSEFLEKARKLAPLVDAVNVTDNQGATMRISPL
AAAALLVREGIEPIYQITCRDRNRLALQSDLLGAAALGINNVLALSGDHISFGDHRAGKP
VFDLDSVQLLHAIRGLGEGMDLAGKSITGLPSFFVGAAAAPEAEPFELTTFKLEKKVVAG
ASFFQTQAIFDPERLALFAEAIKPLQVKVIAGILLLKSAGMARYVNNNIPGLKVPAALIE
ELEKATDPLAAGVDIAKRLAAACKPHCHGLHIMAMGREDLIPEILESVKSEE
>A0A354BG84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
AGAQFFQTQAVYNPDVFASFMKQVRPFNVKVLAGILVLRNHKMAEFMNANIPGMAVPKEM
IDELKAAGDRAEDVGVDIAVRSIKAVRPHCDGVHLMAIKATHRLAEIITKAELG
>A0A1Z9CAM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium TMED108|TrEMBL
MKITDYLKKSNKTLFSYEIIPPFRGGSIDKVFNLVEELMPFDPPFIDLTSRSAESYYQDD
GSGKLVEHIRRKRPGTIGISAAIKNKFNVETVPHVLCNGFSKEETEDALIELNYLGIDNI
LAVRGDELRKRKKNQDQISNKYASDLVKQIQDMNTGKYLEDLLDANKTNFCVGVGGYPEK
HFEATSLDADIETLKYKVDCGADYIVTQMFFDNNIYFQFVDLCRKNGIEIPIIPGVKILS
LERHLKALPKHFYLNIPPELVSSVEGKSKSEIKIAGIDWATNQVQELVDYGAPCIHFYIM
SSAKSATKVVSNFI
>F0M4H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3)|TrEMBL
MMFPVRIEIIPSEGIVEQVQARVPRTTTLSVTCLPHHGIERTMRTAIELSDDGYTVVPHL
AARSIRSRAELTGIVRACDAAGIREVFVIGGDRKQAAGNYDSALPVLEDIAQYTGGLMLA
GVAGYPEGHPAVSPLDLLDGLLAKQHLASHVVTQMCFDAGKIHDYAALLRREGVDLPVWA
GVAGSVPRTKLVALATQIGVGSSLKFLSRKGPLVRNLLGGDRYSPDSLITGLETQPGSIT
GIHLYSFNNVGAVPTLLGNRTVVLR
>A0A3N9RZJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. LASN5T|TrEMBL
MTTSYDQLREARTALDTPLFAGLPGDIRVSFEFFPPKTDALMTQLWDVVTTLAPLEPQFV
SVTYGAGGSTRDRTHGTVARIISEARLPAAAHLTCVDASKAEIREVAEGYWEAGVRHIVA
LRGDMGAPGVPFTPHPEGYANAAELVAGLKAIAPFEISVAAYPESHPDSPSVQADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAAACGAA
IPAWMDGLFEGLDTHPASRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPGRPALEKAA
>G2FFT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|endosymbiont of Tevnia jerichonana|TrEMBL
MTSQTKTAPSISFELFPPKTGQGFENLKRTISQLNQAKPEYFSVTYGAGGSTQERTFASV
DWLREQGIETAPHLSCIGASVEETVAILQHYRDQGVNRIVALRGDLPSGAGLGALGELNY
ANELVSLIRERFSDQFRIEVAAYPEFHPQAPNPETDLANFKRKVDAGADSAITQYFYNPD
AYFRFVDECSRLGVEIPIIPGIMPITNYSSLVRFSDACGTEIPRWIRKRLEGFSDDLESI
RAFGLEVVTELCRRLLEGGAPGLHFYTMNQSEPTLRLCDRLGL
>A0A1I4CCB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. 1_12|TrEMBL
MLKEKIINRMPGILTYGMTPPKATNLPEKIAEISQKQCERIKGLDIDALILYDVQEEADR
IEHERPFPFLPTIDPTTYSDVYLNQLLIPKINYRCVGKYTETQLVDWIKADEDQERFSVF
VGGSSSKQEVKLDLTEAYKLSKQFNRNLTFGGVVIPERHMMKNDEHIRVVNKMKNGCNFF
VSQATYNVEASKNFLSDYFYYCTNYGIEMVPILFNLAPCGSPKTLEFMKWLGISIPKWLE
NDLINSNDVLDKSIRLSQKIFEEILDFGLEKGIPVGCSVESVSTRKVEIEASLQLVKDIK
STLDKRLKLAVVN
>A0A1H4UZW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus jostii|TrEMBL
MTFDSVRGRASEGWVTRTPSIVDRIRSSGDGRVPFSVEFSPPRDEAAEARLWRAVREFER
MGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWQKHPEGVEYAEDLVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSV
RRMLELSGSSLPAQLEKRLAAAAGDGPEENRAAVREIGIDLATEMSERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSGVADPAPVTPTPVS
>A0A208XHH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pigmentiphaga sp. NML080357|TrEMBL
MSSSVPSDTAPADAAPVFSLEFFPPRDIAAQERLVRTAKQLHGLHPHFASVTFGAGGSTR
DGTMLAVTMLQKLGYEVAPHLSCIGSTPDSLRDILYAYRQAGIRRLVALRGDMPSGMGDM
GELRYARDLVRFVREETGDWFHIEVAAYPEMHPQAHDPEADLDHFVEKMRAGADSAITQY
FFNADAYFDFVDRATAKGVLAPIVPGIMPITNYTQLARFSDMCGAEIPRWIRLRLASYGD
DKASIRAFGHDVVTELCQTLLDGGAPGLHFYTMNQADSVQAIWKELER
>A0A4Y3RM85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces gardneri|TrEMBL
MNPTFSFEFFPPKTDKGERTLWDAIRRVEALSPDFVSVTYGAGGSSRDRTIEVTKRIAAE
TTLRPVAHLTAVGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRGAWTPHPQGFTYAY
ELVELVRSLGDFRIGVAAFPEGHPRSAGPADDLAHFVAKCRAGADYAITQMFFDPEDYLR
LRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAKDDPAAAYRIG
VEHATAMGLRLLDEGAPGLHYITLNRSTAAPEIHRTILSARRVAAHV
>A0A4S4HVX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. HUB-I-004|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDVSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A081C8G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Vecturithrix granuli|TrEMBL
MNTNAFKAGSRLEKVLYAGHFAVTSELGPPKSADVDVILTKVGYLKGYVDAVNITDNQTS
IVRMSSLATGLIAMQHGLEPVVQITCRDRNRIAIQSDVLGAYALGIRNILCLTGDHQKFG
NHPTCKNVYDLDSIQLIHTLKTMRDAKTFLCGDEIRNSKKSPIMEPRIFIGGAANPFGDP
FEFRVIRLAKKVKAGVDFIQTQCIYDMERFEKWMALVRERGLHEQVKILAGVTPLKSAKM
AMYMRDHVAGLKIPDVYIERLIQAKDAAAEGINICVEQIQHLRTIAGVAGVHIMAIEWEQ
RVPEIVERAGLLPRPEVK
>A0A6G2ZUB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4915|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDRVTAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A1V6FZL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium ADurb.Bin069|TrEMBL
MPGDFLAALGERVLVCDGGMGTSLYARGVQINACFDELNLSQPHLVREVHRGFLSAGADV
LETNTYLCNRHKLGPHGLDGRVREIILAGVRLAREEARGSAWVAGALGPLGVALEPYGRL
SAAAARAAFRESIDALIEGGVDLLILETFGCVEELLVAVAAARDAREAARRSLPIVAQLA
CGQDGMTLGETPVGCAAAMLADAGADVVGANCGVGPRLMLRYVQEMAAAVRAPLSAQPNA
GLPEEVDGRLMYVSTPEYFATYAKRLIRSGVRLLGGCCGTGPEHIKMLARTVRALSPGRV
AVAAAAAPPAPPQIRPLPAAEKSSLAAKLARGEFVTSVELLPPRGSNPEKARAAAALLRS
AGVDAVNIPDGPRASARMSPMCLASILQREAGIETVLHYTCRDRNLLGMQSDLLGAQALG
LRNILAVTGDPPKLGNYPDATAVYDVDSIGLVRLIANLNRGLDVAGNPLGEPGALHIGVG
ANPGALNLEEEVRRFKRKVDEGAEFCLTQPVFDRSVLERFLEKTAPHRIAVLIGILPIAS
ARVAEFLHNEVPGMQLPDRIRAAMHAAEARGGAAEAGIEIAREALLQMRDLAQGAYVMSP
AGGAKTSLAVLRVLPGFESPSA
>A0A849E4H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anderseniella sp|TrEMBL
MSIVSPVSANFAPGGNPRVSFEVFPARSTMQSDGMAELARVMRKYDPLFTSVTYGAGGTS
HQASFGTIGQLLGVDGLDVVGHLTCAGQSKAQTDAVIERYAAQGVKGILALRGDMPGITG
PYQPHPEGYENGAGLAAAVIARGGLDTYVAAYPEVHPASGSGHACIANLKTKLATGAKAA
ISQFFFDNRDYFHFMEHVRAAGIYQPIVPGILLIHDFAKVASFAGKCQARIPDHLHAAFD
GLAPHSTEHKARACELAGQQIMQLGAQGVDHVHIYSMNRPDLVDQTCKLAGIAQTARIAA
AM
>A0A6H2JNY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mojavensis|TrEMBL
MGLLEDLKKQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASADDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGMNCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSAAEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKHVKVRAKELVT
VQHERTEPGLDEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHLTCRDRNIIGLQSHLMGLDTLGLHDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKMDCGADYFISQPVYSEQQLVDIHNETKHLKTPIYIGVMPLTSSRNAEFIHNEIPGIKL
SDSIREKMARAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTSELTSYIK
QKDEQRQNIYLH
>A0A3R7RWT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED92|TrEMBL
MGPNTTVPVSFEFFPPRDETARHKLVTGTAETLAGLQPEYFSVTXGAGGXTKEGTKQXVT
GLMSNDWNTVPHLSMSGADPQDTLDLVSYYKDLGVRKILCLRGDQANSDAPEPQYAEDLV
RLIRQEFGDHFDIVVGAYPEVHPDAASSETDLEYXKRKVDAGADVAITQYFYNIDAYAYF
VEECRRLQVEIPIVPGIMPITNYESLCRFSAKAGADIPRWLDKAMALRQHAEKDLTEFGV
EVVTRMCXKLIAMGAPALHFYTLNRWGATTKICNNLGVQSG
>A0A3E1P682|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga silvisoli|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMAFKPAFINVTYHRSEHMFKKR
SDGTFEKVEIRKRPGTVAICAAVMNHYNVDAVPHLICGGFSREETENALIDLNFLGVDNV
LVLRGDAPKNEPSFEPEPHGHRYAEELLHQVVNMNNGMYLEEDLQGGVKTKFCIGVAGYP
EKHFEAPNLATDMSYLKRKVENGADYIITQMFFDNQKFFDFVKKCREMGITVPIIPGLKP
MTTRKQLTVLPRAFHVDIPNDLATEILKCKTDKDVELVGTEWLIQQSKELKEFGVPVLHY
YTLGKPEVIRKVVEAVV
>M2UXG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O)|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDEALEQAQVLGIRNILALRGDAPRSEE
YRDEDTPPEQDSNKDFTWAVDLVRYIRKQYGDYFCIGVAAYPEGHSDQSHPEHQDPVADL
PYLVEKTKAGADFIMTQLFYDVEAYDKYEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHAKLPTDIIARLDAVKSDDELVKQVGVQIMDEIVEHIKVRPDTCRRGFHFYTLNL
EKAVSHILEDTKLIPSTLIDDDEVIVETTPAINLEPPPNGMMPHRRRSSAVNSGPRNRVI
VSHVSAARSSNPSYEATEEEAGIPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKNDISTLFRRHIEGDLEAIPWSEQGLSP
ETLTISKQLLALNAKGWWTVASQPAVNGIKSTDPVFGWGPKNGYVFQKPFVEFFIPASEF
ATLQPKLDAHDQITYFAGNAAGDFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIWREWQRIYPPRSAPSTLLGELRRDYWLVNVIWGDFVNGEGLWEFLLE
>A0A2H0LM99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG11_big_fil_rev_8_21_14_0_20_45_26|TrEMBL
MRLSKLYRSQKPDISVELFPPKTKEGTDKIFEEVKILNQFHPTFFSMTYGAGGSTRDLTL
ELVDELKNKIGVETMCHLTVVSQSKADVRNVLNFLKEKGVYNLIALRGDPPQGTEKFQPH
PNGFRHAVDLVREAKRDNFFSVAVAGFPEKHPDAPTLESDIQHLKEKVDAGADAVITQLF
FDNRFYYGYLDKVRRAGVQVPVIPGILPILSTQQVKRFTALCRSQIPPAVGRMLAKYEND
SEAATQYGIELATQQCQDLIKQGVPGIHFYCLNRSRSVKTILSNLNQK
>A0A5B8XNT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradymonadales bacterium V1718|TrEMBL
MTSFLDRLKEGPLVFDGAMGTQLYERGIFINKSFDDANLSNPALVQAIHADYVRAGADII
STNTFAANRIKLKRHGLEDKVRDINRAGVELARAVCPEECFVAGSIGPTGQIPTMMSDSE
LQEIRAAYAEQALILAETGVDLIALETFRLLSEIRIAIEAIKSVCELPIVALMAFDSEHR
TGDGATPERVARLLVEWGADVIGANCLEGPHVVFDVVEEMVNHGVPVCAMPNAGYPRKVD
ERLIYMATPEYFGVYARRFFKAGIAIVGGCCGTGPEHIQGISAAARMMGGGRSTKPKARL
SVVESAQVAGLAEVPLAERSGLAAKLQRVWRDRICQGSAPVNRENFVVSVEVNPPAGLDP
SKSINAAKMLQRHGIDVINIADGPRASVRMANWAMASMVQRELDMEVIVHLCGRDRNLLG
LQSDVLAYHALGLNNLVVVTGDPPKVGDYPHATAVFDLDSIGILKMINNFNRGIDPAGRD
VGATTQFFCACGAEPAAADYERELRRLEEKKAAGASFVMTQPVYDPAVLDKFLSDIEHLG
LPVLVGILPLASYRNAEFLHNEVPGMSVPDDVRKRMKDAGEDAAQEGVRIAKETLNAVVD
RVVGAYIMPPFGRYHTAVEVLSDIPGYSVDAAPQASEAAQR
>A0A1W5LFJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylacidiphilum sp. RTK17.1|TrEMBL
MATLIDRLNESLLIGDGALGTYLYSLGVPRNYCIEELSLSQPYLIEKVHKDYIEAGAKII
RANTAEANAYHLSFFKLEKKLKEIVSSSIGLAKKALGFKEGWIAGTINPIWVRPADPPID
LSTRRTLYEEQISLLLEEGCDLLFFETFTDLSDLLLGLELARNKGAQFLFAFVASFEEGK
LSSGQSLKEAFSKLREAGALLVGINGASGVQASLHLLEEIEKKETDLLGAYPNAGKPEFY
EGKLTYSASPSYFGQNVLKFVEEGLNLLGGDYGTEPVHVAAMAQAAVGVKPIKRKLAKIR
LRYEVGEKETLPQVEPSLLDRLNIKPVFMVEYDSPKTLSMGKFLEGVKAIEKAGADALTL
ADNSLAILRVSNFAAAIHVRRVSKLIPVLHVACRDRNLLGLQSELMGLGTLGFRHILALT
GDPAKSGDHPGATSVYDLNSIGLIRLLAGLNRGVNAAGKDLKGKTDFIIGCAFNPNTVQF
DAQVRKLEAKLAAGARFVMTQPVFDFELIKKIFNYLKPLGVPVFVGLMPILNYRNAEFLH
NEVPGISIPEKIRRRMKDLEGEKATEAGVEFARELGEEILSHFRAIYLITPFLRYDISVR
LLESLQSTKTA
>A0A7Y0HFH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pacificispira spongiicola|TrEMBL
MSGNIKIGFEVFPPKAGTSVTFESGVAALASAGDYVSVTYGASGSGRERSEIALDVLSKN
GLAGQIAAHLTAAGQSREDIDALARHWKSIGVKRVVALRGDAPAESDDEYACAAHLTEGL
TRIGGFDISVACYPETHPKSTSEAAELDHLKRKFDAGAARAISQFFFEPDLFLRFRDRCA
AAGIDKPIVPGLLPVASLDSLHRFAGGCGASVPDWIDTRFGGLEDDPDAFHALSIATTVS
IAERLIAEGVDHIHLYTLNRVGDALTISRALGRIGELPAPAPAQPLKTEEAA
>A0A1W9R1E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium 4484_249|TrEMBL
MRIPFPEYLKNNLVLFDGAMGTELYNKGVFINSCYDELNITRPKLIKEIHESYVKAGADV
IETNTFGANRLKLLKHGLEDKIYEINYAGAMLAREVAGDDVYVAGSIGPLNERLEPWGPL
SEEDARKIFVEQAQGLIDGGVDLIIFETFSDLHLIQQAIFAIKEKYDIPVIAQMTISNDG
NSLFGTPPELFATKMAKWGADVIGINCSVGPKPMLDALEKMSEVAEVPISIMPNAGTPVD
VDGRNIYLSTDDYFAEYTRHFIQAGAQIIGGCCGTDPSFTKKMRKAIQSIQPRKIIYKQV
SVKTVEKLVKTKPTCDKSDFSRKICKKEFVTSVEIVPPRGPDAAKAIEQAKIFKQAGVDA
INIPDGPRALSRMGASYLSLMIQQQADIEVILHYACRDRNLLGMVGDLIGAYAAGIKNIL
IITGDPPKMGTYPDATAVFDVDSIGLTNVANCLNSGQDLGGNPIDTPTGFLIGVGANPGA
IDLDYEIKRFEWKVKAGAEYAITQPVFDNELFYKFLKRIEQFKIPVIAGIWPLVSIRNAE
FMNNEVPGASVPENIMKRMYATKSKEEARELGLEIARETIRELKADIAGVQVSMPFRKSK
YPLDVLKEVL
>A0A2M8B231|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_9_14_3_um_filter_65_9|TrEMBL
MKKSPLIFDGAVGTMIYDHGVFINTCYDELCLTNPKLILRIHRDYVEAGAEVIETNTFGA
NPIRLKPYGLAEKTEAINRAGVRLAREAAGDEVFVAGSVGPCTESRQRMPDAFAAEVEAA
FRAQMGALAAEGVDLFLLETFSNLNELQLAARVAKEFGEPVLASFVLNDRGETALGMRAE
TMASALSGDANVDIVGINCGTGPSGAFDALQAILPHTGKPVVVMPNAGMPREISGRVIYL
TSPEYFTEYAKKYIELGVRGVGGCCGTTPAHIRMAARAVKPLRVGKRRFEVKPLLRQESL
VYAVPTERKSRLAAKMCAGEKVTSVELVPPKSSDMTALLDRARKCAEAGVDAINIPDGPR
ASARVSPMISALTISREVGIETILHYCCRDRNLIGMQSDLLGGYAAKLANFLIITGDPPK
LGEYPDVTGVFDVDSIGLVQVAANLNRGLDIGGNPIDPPTGLFIGVGANPCAVDLSREIE
RYFRKIDAGAEFAITQPVFDPEALLRFLDRVDGYRRRIPVLAGVWPLVSFKNAEFMNNEV
PGVVVPKEILERMSRCRTREDGRKAGIEIARGIIERISDRVSGFQVSAPMGHVETALAVL
GKST
>A0A6N7VJF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidaminococcus fermentans|TrEMBL
MKIIDLLKSPKVCVSCELFPPKKGSELEHAQEIVRTIAIQGVDYMSVTYGAGGTAVGKSV
ALVSEIERCGVPALAHLTCVGADEQKIEGVLDQLKAANVQNVLALRGDLPQGQEHPLGDY
AHASDLVKKIKSYGDFCVGGATYPEGHPEAAGLDDDLEHTKMKVEAGCDFLVTQMFFDNS
MFYNFMYRMLAKGINVPVVAGIMPVTNLKQIEKIFTLSGTPVPAPLRAMAERFADHPAAL
KQAGMAYAIGQIVDLIANGFTNIHIYTMNKPDIIGGIRSNLSEIIRC
>A0A2X2RMV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga ochracea|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVESCKNNNEVKQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A329ZLW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. 10-6591|TrEMBL
MLDSLITHIHSSANFLSLEITPSLSASLDSKLLYSLKSFQKVTCFVCTDSPLARLKPSSI
LSSFKLQNALQKPVICTLSMRDRNSIALCGDILAANELGVRAFLSLTGDPINLGDCKESK
GVFEDNSLKLAQIITSLNEGYAFNGKELASKVQKIYNFHTLNSYANNMDTLVNKMSKKLA
SSECEGFFTQPVYERKSAEFLLHNLQKLNAKYNRNVELILGYYPILSFKAALFLRDKLPG
VFVPEDFITRLESAAEIGKEEEEKVGFELSSKLLLELQTLSNKFHFMNPDKFKLFEHFF
>A0A178IJ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutaceae bacterium TSB47|TrEMBL
MIPDLPIADLFAQGRPLRSLEFFPPKDDAGVAGLRETATALRRIRPDFVSVTYGAGGGTR
ERTTQVSALLRGELGFTVMPHLTCVGHSRAELEGMADRIHAGGFRNIMALRGDPPRGATE
FKPAPDGLRHANELVALLKARHPDFCLGVGGYPERHPEAPSMEADLDNLKRKVDAGAAFV
TTQLFFDNNAYYRFVDRCRARGILVPVVPGIMPVLSLNQTQRFTQMCGVALPAVLTKRLE
AAGDDAGTAEAVGIDWALAQIRDLLANGAPGYHVYILNRAKSALALAAGLAA
>A0A2M8AYI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_9_14_3_um_filter_65_9|TrEMBL
AHLTCVDASKTEIEEVVGDYWDAGVRHIVALRGDPPRRNDAFAPFVPHPDGYASAAELVA
GIKALRPFEISVAAYPEVHPEADCPQTDLDNLKRKLDAGATRAITQFFFSPECFFRFRDA
AAAAGIDSEIVPGILPISNVATTRKIAGLCGAAIPDWMERLFEGLDTLPAARQLVAATVA
AELCRKLYTGGVREFHFYTLNRAELAYAICHLLGMRGGETEEEKAA
>A0A5B8BVP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanicola sp. D3|TrEMBL
MHVKLMIVLRVMSLFHIRANATTKTDLKHTRPVMPAAPSVSFEFFPPQNLEASFRLWDTV
NVLAPLNPSFVSVTYGAGGTTRELTREAVATLHKSSGLNVAAHLTCVDATREETLGIARG
FHEAGVREIVALRGDPPKGSDGFEAHPEGFANACELIAALKDTGDFKIRVGAYPDPHPEA
KGEGADVAWLKRKFEAGADEAITQFFFEADTFLRFRDACAAAGIDKPVIPGVLPIENFKN
TARFAARCGAHVPQWMVEAFEAAERDGREELLATALATELCSELLDEGVEHLHFYTLNRP
GLTRDVCRAIGVQPEQALENVA
>A0A4R1T8X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PP-WC-2G-219|TrEMBL
MSTRTLYPAERGDLRLSFEYFPPKSDEMDAQLTRTAAALNAYAPEFVSVTYGAGGSTKAR
SLTTVRRLIDDCAVPGTAAHLTCVGATRAEVDAVVEEFAAAGVRHFVALRGDPQGGIGAQ
YQPFPDGYENAAALVAALARSGRFQISVSAYPEKHPESSDVDADIDMLKRKVDNGATRAL
TQFFFDNNDFERYLERVRKAGISIPVVPGILPINQFGQVSKFAALCGARIPEALSARLAH
LDESPEERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFKRTDDAAVE
GAAA
>A0A6N0X0N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. CL5.1|TrEMBL
MTLSFNQLEEARRALDAPLYADVAGDIDVSFEFFPPKTEKMEETLWHSIGTLAPLAPRFV
SVTYGAGGSTRERTHATVARIARETAIPAAAHLTCVEATREEIDAVAREYWAAGVRHIVA
LRGDPPVQGARYQAHPGGYENAAALVEGLRRLHPFELSVAAYPESHPDSADAAADLDNLK
RKIDAGATRAITQFFFEPETFFRFRDRAAAAGIAAEVVPGIMPVSNFAAVQRMSAMCGTA
VPPWMGRLFEGLDDLPDARQLVAATLTAELCRKLYAGGVKQFHFYTLNRAELSFAICHLL
GLRAKIGAQAAAA
>A0A7U8D755|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia mallei JHU|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A7G2JTH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia grimesii|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLDAAPHLTCIDASPDQLREIATDYWNSGIRHIVALRGD
LPPGGGKPDMYATDLVALLKDVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAIA
>M7NFZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paeniglutamicibacter gangotriensis Lz1y|TrEMBL
MSSEKSPPLQRDLPAVFGNLGYEVLPFKSTAENVVTWIPKSTCLTVTASPPKGIEATIAL
TERLAAAGYQVAPHLSARMITDKVQLTEIVTRMKASNVNEVFVVGGDAKEAAGEFRDGYD
LLKALDEIGHHFGEVGIGGYPEGHAFISRANLASSLREKSELATYIATQICFDAKTIASW
AREVKADGVNLPIRVGMPGAVTRQKLLRISMASGVGDSVNFLKKQQNMFWRFFVPGGYSP
GKLVNGLKPFIGQPDNNITDFHVFTFNELEKTEIWRQKSLLRYSK
>A0A2P8QZL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter blaseri|TrEMBL
MLKDKILNNEPGILLYGITPPRMNLPNSEYERIGKIHKQRFEEIGVDGIIIYDLQDEKSR
NSSERIFDFVQTLDPQKYYEDFLHTSIEPIIYKAVSKYDTATFYDFLQKEKDYIYVFVGS
SSSKVVPKLTLDEAYRLTKNSNFNSVLGGICIPERHVIKKDEHIRMIEKSKNGCKFFISQ
AIYNVENAKKFIDDYAQTNFANIPIIFTFIPCGSKKTLDFIKWLGIFVEDRFEKKLIDSN
DMIQTSINLSLEFFNFIYKYSLSKGISVGANVESISKQRDEIQASLTLLDEIKKIIKRAS
YSYRS
>A0A2M7SHM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_10_14_0_8_um_filter_43_12|TrEMBL
MANYMKKSVPGMDVPDELIERMKAAPKEKKAEEGINICIETIQRLREIEGIHGVHIMAIE
WEEMVPEIVKRAGLFPRPHIEG
>A0A0Q5P4E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf343|TrEMBL
MTISVNQLAEARCALESPLYADVGGDLDVSFEFFPPKNEKMEEQLWESVRTLEPLGPRFV
SVTYGAGGTTRERTHATVARIQRETSLAAAAHLTCVEATREEIDQVAEEYWAAGVRHIVA
LRGDSPTAGTKFASHPGGYENAAALVAGLRKLHPFEISVAAYPENHPDSADAAADLDNLK
RKLDAGANRAITQFFFEPETFFRYRDAVAAAGISAEIVPGIMPVSNFASVQRMSAMCGTD
VPAWMGRLFEGLDVHPAARQLVAATVAAELSRRLYAGGCKQLHFYTLNRAELAFAICHLL
GVRAKAAVQEVAA
>A0A2T1CFU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|filamentous cyanobacterium CCP2|TrEMBL
MSDLHAQPSPFQPAPSRLYRAVQTGEFLVTAEVMPPKGGCVSHMVDMAMRLKGRVHAMNI
TDGSRAVLRMSSLAASAILVQQGLEPVYQIACRDRNIIALQADLMGAQALGICNVLALTG
DPVKAGDHPIAKSVFDLESVRLLKLIGKLNQGFDFNDKPLTDGATKLFVGAAVDPQCPSW
SGLQRRFERKLAAGAQFFQSQLISDFDRLEKFMDQIAVGCNKPILAGIFLLKSAKNAQFI
NRNVPGVQIPQHIIDRLAQAENPLDEGITIAAEQVKIAQQLCQGVHLMAVRREDLIPEIL
DRAGVKPVKADQG
>A0A1H1ET19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. UC 17F4|TrEMBL
MSVLKKALLDGVFTCVVEYVPKPSSERFTAFEALMEQSRLHEWPLVPAVADRVGGKFDIA
PVDACAALKGPTPALIHFSGKDRERSDLLSELDRMDRLGVNQLLLISGDRLPGHQPGQHP
VRYLESVPALQIARAARPDWLLGAALNPFKYREEEGCAQYLKAHKKLAAGADFLTLQLGF
DAKKHIEAITWMTRQKTAKPLLACVMGLTEKRASLLKSVPGIVVSPSMLGVLAAEAAVSK
EHARSRCTDRLALQIVGLRLMGYAGIHLSGIHTAQELEALEQRIAVWVKNIGSLEHWSAA
WADSWQPPGQLAVTFNPPGASWYLGESSVKATSKETLRYHVLAGFHSSLFSRTTLLGKAL
GWAVRRPVWSSYRGASLLRQLERSLKRPLVGCDTCGQCRLEDTLYICPETCPKGLSNGPC
GGTHLNRCEFGDRECIHSVKYRTAKSVRQIQILTDRLIPCVEQGSRHSSSWPRWFEADAS
QTRGTSD
>A0A7C1J0Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium|TrEMBL
MENPFLERLKKGPILCDGAMGTMLYQKGVSFERCFDELNLSAPELIADIHRAYIKAGAEI
IETNTFGANRYRLSTYGLEKQTVKINRQGAKIARDAREIEGKSVFVAGAVGPLGKPLYPI
GKIKAKEAFDAFREQAEGLLEGGVDLFIVETQSDLKEVEQAVLAIRTLSQLPIIAQMSFT
EEGKTTTGAGPAEATKFLSNLPVEVIGANCSVGPQGVLAVVSQMAHETKKYVSAQPNAGL
PRLVSGRFVYSTPPEYFAEYTRYFLATGVTLVGGCCGTTPAHTEAMAEALVHFAEKKVLP
ETVEVISFPAEEEKREFKPGRPTGLAAKLGKKFVISVELDPPRGINPEKLLKAAARIKEA
GVDCVNIGDSPMARVRMGCLSVAYMVHQQVGIDVVIHFTTRDRNLMGIQSDLLGAHALGI
RNVLAITGDPPTVGDYPHATGVFDIDSIGLLKVLAKLNTGADWNGNSIGNPTEFFIGCGV
NPTAEDMEREVERFGQKLEAGAQFVFTQPLYDRRVLEEFLKRVKGVKIPILLGILPLQSS
RHAEFLHNEVPGITIPEPARRAMREAKDKGPEVGIEMARVFLEEVKDLVAGTYLMPSFGR
YEQVLEVVKNVLPKEEVVKTTR
>A0A8J6Y839|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Polarisedimenticola svalbardensis|TrEMBL
MARDFNKLVGERVVVFDGAMGTRLYDLGVFLNRCFDELNLSAPSLVEDVHRSYVDVGVDV
LETNTFGANAVKLGKHGLGESLDRINETGAALARNAAGESVLVAGAIGPLGVRIEPWGPT
AVEEAAEMFAAQAAALERGGVDMFSVETFFDLPEIEAAIRGVRSVSKLPIVAQITLEDDG
TSLEGVAPELFGPQLAALPIDGVGVNCSVGPAAMMDAVEKLAAVVDLPVIAQPNAGKPRI
VENRNLYLCSPEYMATFASRFIAAGARIVGGCCGTTPDHLAAIRRAVRAAAPMAARTRPP
RIELPEDRTGKQAKAVPMAKRSRFAARLAEGRFPISVEMLPPRGVELDKCLKGGERLRDA
GIDVINIPDGPRASARVSPMAMAVRLERELGVETLIHYCCRDRNLLGMQSDLLGAHVLGL
RNVLIITGDPPKLGDYPDATAVFDVDSIGLTNMVQRLNHGVDVGGNLIGEPTAFCFGVGV
NPGVLDLGREISRLEWKVEAGAEFAISQPVFDVEQFLAFKEKIAHLDVPILAGIWPLASY
RNAEFMNNEVPGVHVPESILRRMQKTETGETARNEGIAIAREMLTALLPHIQGAQIAAPF
GRYLTAVDVARAVPADRRGD
>A0A7K3J1H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSIIKPARRWQPAFYPFKKEKFSARLLGRIELAVKGPVFGCRMCGNCLLQETAFICPMEC
PKGMRNGPCGGITPEKNCYVDESRKCVWYAIYERSRKMGRQKMLLEVLPPLDWYKVGTET
WGVVVRQVRKTGIWTFIRSLFLKDKIKKSEVWDSVFKTIRQPAWWMGDSEYHKPAYEEPA
SLLEKKLRNGEFVIATEVSPPLGANPAKIIREIELVRPWVTAVNFTDASSASPKMSGIAC
CKVANDLNCEAVFQIAARDTTRTGLQSAVIGSGQMGVRNILCVTGDNPRVGPSPASDMNF
VDVDSVQMLWILRRMRDEGIYLDGRKIKYPPKFFLGAATTPFASDPELQAIRDQKKINAG
AQFFQTNLIFEPDRLDQWLEQLDKRDLLDKVYILAGISPLKSYKIARYLHDKVPGVFLPK
DILTRMEKAGDGASEEGFQIALELIDSIKSKKGIHGIHLMTMGWEEIVGRLVAESGILQQ
>A0A5B2X0T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solihabitans fulvus|TrEMBL
MSSVVERLRGDGPVFSVEFFPPRDAEDEQVLWRAVRELEPLDPAFVSITYGAGGSSRDRT
IRTTGRIAQETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILAVRGDPPGDPYGEWI
RHPDGLTYAEELVRLCRELGDFCVGVAAWPYGHPRSADLDDDTVHLVRKLRAGADFAIAQ
LFFQPEDFLRLRDRVLAKGCETVLLPGVMPLTTLRMLHKTAELAGVPVPPHIAAKLERYA
DDPAGFRAAGIDHVTELCERLLAEGVPGVHFYTLNRSKATREVVARLGLVPART
>A0A2U3WPV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odobenus rosmarus divergens|TrEMBL
MVNEPRGDGGPPPRSEGSSSGSESSKESSRCSTPGLDPERRDRLREKMRRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSQEQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRH
IRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFARYLSGEPNQHGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPTPEQGAEAL
>A0A7J6N0V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perkinsus olseni|TrEMBL
VPRAIADQLEQVKGDDQKVKDLGVEICVAMCSQIMSYGVDHCHSSGGLHFYTLNLESSVS
RIIERLMMVDSHVATRALPWRPSKASSRQEENVRPIFWSNRQKSFIQRTSCWDEFPNGRL
GNQASAAYGDFELNFRSYSKETQDKVAADRRRMWGDHVPNGDHVRRVFTAFIKGEVKRLP
WCTESPTEETLFIQKQLIRLNQCNMLTINSQPRVNGALSTDPYVGWGPGGGFVYQKAYVE
FFCPESQLEQLIRGIEGEKYESISYMAVTADGSKVKSNIPPQGQVNAVTWGVFPNSEIIQ
PTVVDVTSFMAWKDEAFALWNEWMDVYPEDDHQSRQVLSFIRDHYFLCTVVDNDFVAGDL
FSKLTKICTPIPWETLRIENPSESDGHEVPETSLAVIAEVYSPRPKPTDLSPRHETEDDI
TSFAPL
>A0A7W1HPL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacteraceae bacterium|TrEMBL
MSPNLRELLATRVLIGDGAVGTLLGERGVGFGHPYARANLSHPEMVTDIHVEYLRAGADV
IETNTFAANRFKLETHDLEERVREVNAEGASLARKAAYTVAGTGDRALVLGAIGPLGRPL
APVGPVSPERAKSVFLEQAEALLEGGADAILLETFTDLVELRLAYEAVGALGAPVLAYKT
FVEDGETLAEGLPGRAAREISSWGADLAGANCTVGPQRMVEIIGQMADAAGPVAALPNPG
LPQIVGGHIRFSKGVDHFAEYGIKLAEAGARLVGGCCGTTPAHVKALSEALQDFRVEGKR
TRRRGSVAERTWLTEVSVEPVSEFAERLRAGFAVTVEVDLPRGNAIEQVVEAARRLKERG
VHAIDISDGARARLRMHPVAAARIVQDEAGIEVVAHISCRDRNIIGLQADLLGAAALGVK
NILAVTGDPAQIGDYPEATSVFDTDSVGLVHILSRMNRGEDLAGNPIGEPPGFLVGASFN
PTAEDLDEEVEKLRRKVEAGAHAFWTQPVFEIGGLENALERIGVDGVCILLGLMPLRSAR
QAEFLHHEVPGIDIPKHVREKLAALSPEDAPKYGVEVAQELLIAARPLIGGAYIMPPASA
PDLA
>A0A369Q2V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter chinensis|TrEMBL
MKITDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADHSFVPTKGGHCYATDLIQHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNSDFKYLKKKVEMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLTQLTVLPKVFHIDLPDELTDALSYAKTNAEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKKIARAIF
>A0A221R6H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinomonas sp. R1AF57|TrEMBL
MSPPTLIDAPTSIAAPAPVALSYELFPPRSPAASETLWKTIRELEATDPDYVSVTYGVSG
SNHDTALDLVDRLQLETTLRPLAHLTCVGGSPAELSTVVNELLDRGVRGILALRGDTPRD
GVLPQGALRYAQDLIELIRRVELRRSAQFAAGKVAIGVAAYPTKHPESPSEAHDIEVLLA
KQRSGADFAITQVFFHTDQYASLLHRARRAGVTIPVIPGIMPLTSVRRIEKLASLSGVLP
DASLVDRLRSAGDDEAAARGIGIEASVALAEAALEAGAPGLHLYTFNEHEASLEVLARLS
LPRPSRPSLAARRRAAH
>E6R5R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071)|TrEMBL
MKITEKLQKAEKEGRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALKEAKSHGCQNILALRGDPVAGTST
WEPTPGGFMNAVDLVRYIHKHYPGDFCVAVAGFPQGHPETPGTPEGRAQEMEWLKAKVDA
GAEFIFTQMFYDTSIFFDWVKRVREAGINVPIVPGIMPIQNWEKFEKWVQRENIIVPSHF
YEALNPVRGDDEKVRQVGTKLVADMCKTILQNKEAGIKGLHIYTLNLEKGARMLLKELGF
EGRREQIAPLPWRPSLTPSRREETIRPIFWANRTRSYLSRTADWDEFPNGRWGDSRSPAY
GDLDGYPVSIGVTAPDAYNLWGHPTTSFDLHTLFARFCRGDLAKLPWSTQPPASETSLII
EQLAKMNELGYLTINSQPAVDGVRSDDKVHGWGPAGGYVYQKAYLEFFVSPDLLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWAHLYPAGSPSRKLITDTMNTSYLVNIVANDFRDGMSIFEPFLLNQTTVAKVVEGV
KGTVEGVVEGVKGVVSA
>A0A0D1YSH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala spinifera|TrEMBL
MDDRLPSIWSKLDPSSRYFSLEFFPPKTSSGFANLQARLVRMAQGLRPLFVTVTWGAGGS
TATKSLELAEICQRQLGLTTVLHLTCTNMKRKAVDEALEGAKEVGIRNILALRGDPPREE
YKDTDETGSGGEGTDSNEEFVWAVDLVRYIRRQYGDYFSIGVAGYPEGHADENNPEVGKQ
SVEYDLPYLAEKTAAGADFIMTQLTYDIQAYQAYEKRLREYVDEKGEKLFGSIPIIPGLM
PIQSYQIIKRITKLSHAKIPGNILERIEAVKSDDEAVKRVGVDILSELVEQMTELPQPEG
VPRGFHFYTLNLEKSVAFILERTGLIPPVSEQASPAESSDSDAIIDDEKRPGYSEGQGTD
GTARGTLDRTPRFTKRRTSSVNAQPHNRVIVDATLKASHGSKKATQRGPETAPIISRHEA
SEKGTGIPASGPTRKHTLMISEGQGSLGREATWDDFPNGRWGPSDSPAFGEIDGYGPSLK
VGPITARKLWGHPTSHKDITELFRRHVVGELEAVPWSDEMDIDGASSGGSGPLRAETQVI
RKELLDLIETKGYWTLASQPAVDGARSDDEIVGWGPPGEGWVFQKAFVEFFCPRQEWEDR
LKPLLLKYEADTLGWMKTDASGVFESSTDIKQPNTPEKSTTKQTPGTSGISAVTWGVFRN
REIITPTIIEDESFRAWGEEAYSIWSVWRRCFPRGSEEEKFLDRMRQDLVLVNVVGNNYA
GGHSGQGGELWKILLERK
>A0A395L854|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. M14|TrEMBL
MNTFARHDLETALFHNYSLEITGKDIGQIEAARFAIPAGTPINIAFLGNETHAQRIEAAA
RIRQWGFEPVPILSSRRLKSVEDRDELLAGLIVAARPTRFMFVGGDPSSPAGPYKDSLDL
IAGGIIEDHGITHVGIGGYPEGHPRIDRTRLWEALEQKIGLLKARGCTVEITTQFGFDAD
AIVDWIVRVRERGIDVPIRIGVPGPADVRRLLRFAVQFGVASSAAIVGKYGFSLANLVDK
VGPDRFMSRLADGMAGRNLGTVLLHLYPFGGIAETVAWAADAACRQMSARVRGETR
>A0A2S6TB09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha5_Bin3|TrEMBL
MNRNQKEFNIKKLLNNYSIETTPNVYEKYGKFSDLISTDNAVYVTYLPDENSSRVINTAK
KLTNEGFDVIPHLPARTIKDNNELEKYIGDLSEKAGCNKILVIGGGSNQKGNITSSLDIL
KTDLLSKYQFKEVGLAGHPDGNPDISEEELDKAIIEKNEFVKNVDYKAYLATQFFFEVSS
LEIWEQKLNLHNNKLEIHAGIPGPATLKTLIAYAKSCGIGNSIHFLSKQARNITKIMKTR
TPDKLIADLADYKEERPNSKLAKLHFYAFGGIKTTSEWLYDVINSNLEINSKNEFKIIGK
>A0A3B9N2K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVIDKIKNAKSALFTFELLPPLKGHTIQEIYDTIDPLIEFNPAYINITYHQQEVVYKTR
PDGLMEKRVIRKRPGTVAIAAAIQNKYKITVVPHMICGGFTKEETEDALIDFHFLGINNL
LVLRGDPEKGKRKFVPEKGGHTYSSELIEQIMNLNKGKYLHEDLENAMPTDFSLGVAGYP
EKHIEAPNMDTDLEYLKLKVDKGAEYIVTQLFFDNQKYFNFVDSCKKIGIDVPIIPGIKP
VSTLNDSSLLPQTFNIDLPNELIKEIKKCKTTKDVRQVGVEWTTMQSKELIKFGVPGIHY
YTLDQSDNIQRIARAVF
>A0A4S4GW16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MRIIDIINDSPNPVFSFEILPPLKGNSIYKVFDIVEKLKRFDPKFVNITSHHSEYIYKPL
PDGTHRRVSIVKRPGTVAIAAAIQNRYGLIPVPHIICKGFTKEETEYALLDLNFLGINNL
LVLRGDEKGQDSTMGQPNISHEHATDLQKQINLFNEGIGLEDMRIQGIETPFSYGMACYP
EKHEEAPNMESDIYYMKKKMENGADYFVTQMFFDNEKYFSFVERCRAAGINVPIIPGLKP
ISKMSHLTMLPKVFRIDIPEELASRIRECKTDTEVKQVGIEWGIRQSRELLEKGALGLHY
YTMSVSDSVSKIVENVY
>S7SW85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. WSUCF1|TrEMBL
MGLLDELKQRILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLARQAANERAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALLA
>A0A1I2TNY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus hitonicola|TrEMBL
MKITEHLKNAKKTVFSFEILPPLKGQSLNELLEGIAPLMEFNPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFHVDAVPHLLCGGFTKEETENALIDLNFIGVENV
LALRGDAPKTEGRFEPEKDGHHFASELVEQIIRMNNGKYLHEETETSFHTNFCVGVAGYP
EKHFEAPSLKFDLKYLKDKIDKGAEYIVTQMFFDNQKFFEFERKVREAGIEVPIIPGLKP
ITTLGQITMLPRTFFLDLPDALTDELVKCKTNAEVKEVGIAWAIAQSKELVAAGVPSLHF
YTMSKADATYKIAKEVF
>A0A062UEB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas chukchiensis|TrEMBL
MSSLSIANRQKHAAPSVSFEFFPPKSEAMAARLWETVQRLEPMAPEFVSVTYGAGGSTRE
RTHDTVKRIASDTALRPAAHLTCVSATKAEVLDVADSYAAAGVHHIVALRGDPPEGMGAA
FAPHPDGFANSVELIEALSEAGKFEISVSCYPEPHPNSRGWDEDLAFLKAKQDAGAKRAI
TQFFFEPDTYLRFVEKARAKGITMPLVPGIMLQPNFAGLKRMAGMVQATIPAWLDRLYDG
LDSDDETRDLVTATVAAELCHKLADEGVSDFHFYTLNRAGLALSTCRLLGMKPKPAQAA
>G7H1R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia araii NBRC 100433|TrEMBL
MIGLPGAFYTMAGKILLLTGVGDGAGVERGRGVGLAERIAQRDDGVLLFSLTPPRSATSP
DDAQRIADVTLARLESLDLDGLVLYDIDDESDRNPAERPFPYLPTMDPAAFLADHLSRWR
RPVVVYRCVGKYDESSMEEWLARQDPASVLTVFVGASSDDKPRALELPAAQKLRAEVNPK
LQLGGVAIPERHSRTGAEHLRMVAKQQSGVSFFVTQVVYDVSAAKSMLSDYFYACAEAGL
APVPVIFTLSVCGSMKTVEFLEWLGVDVPRWLRNDLAHSDDPLAASFRQCMAAADELADF
ARRLGTPHGFNVESVSNRRREIEASVELAARLRP
>A0A7G5M1G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mumia sp. ZJ1417|TrEMBL
MDLVRRITARGSEFLLFALTPPRITVTPERAQEIADVTQKRLTPLGLDGLVLYDIDDESD
RNPKERPFPFLPTIDPAIFRAQHLKDWSTPVVVYRAVGKYEESDLRAWLEAQDADDALTV
FVGASSRHAQSATSLARAQELWAQTRPNLQLGGVAIPERHSRRGEEHLRLIAKQEAGCSF
FVTQVVYDVNAAKNLVSDYRYECAARGLEPVPIVFTFSVCGSLKTLEFLGWLGVDVPRWI
QNDLRHADDTLQASYEQSLCAARELIGYCRRMGVPFGINVESVSIRLAEIEASVDLAQEL
ERELRR
>A0A524C337|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
GGLDAWVLAGIIPLKGPKMAQFMNKRIPGIKIPDSMISRLEKAGRGLKGAEKRASVRGEG
LRIASETIKEARKIKGVDGIHIMSVGWESAIPELVKGARLHPRPD
>H2JJD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. BNL1100|TrEMBL
MRIQEIFAKKMPVLSFEIFPPKRDSELKDIDETLAILSELSPDFISVTFGAGGSSNNNKT
IEIAKKIKHQYGIETLVHLTCSSYTKQEIDSFISILSENGIENILALRGDKNPNVLEKSD
FHYASELTGYLNKAANFCLAGACYPECHPESKNRISEISHLKEKVDAGSNFLISQLFFEN
EFFYSFIESCRIAGINVPVTAGIMPVINKAQIERIVNLCGASLPNRFRKILNRYENEPTA
LFDAGMSYALSQVIDLLVNDVDGIHLYTMNNPIVAKRICEGIKNII
>A0A518JW54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rosistilla carotiformis|TrEMBL
MSLSQLFRNGGCPISFELFPPKTPAGFESLYEHVESLKQFDPAFFTCTYGAGGSTQNSTL
DVVREVKRRTGKPVASHLTCVGSTQDQLRSYLTEAGALGVDYIVALRGDPPKGETSFTAV
EGGFRYANELVDLIHREFPAFGIAVAGYPEVHQEAVDANVDLENLKRKVDAGADCVVTQL
FYDNDDFFRFRDACQAAGIEIPIIPGLLPITNFAQAQRIASMCKARLPQGLVDRFNENDT
ADWQLKVGIEHAQQQTNDLIRRGIDGLHLYVLNKSQAAAEVLAGVDRG
>A0A4R2J7W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia coccoides|TrEMBL
MKLSEAMKNKMLLSFELFPPKTDKGMENLPGTIEHLCKYQPEYISCTYGAGGTNVGKNMD
VCKMIQDAGTIPVTHFTCIGNTAEGIKEQLQNYLDNGVDHMLALRGDLPFGWTGTGGDFA
YATDLVAYVRKEFGDKIEIAVAGSPEGHIACRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKRWMDAIRTAGITMPVDVGIMPILDQAATINMALSRNGCVMPRKLCEIISKNWIFPN
PFDKDPFDAAVDEKKAAFKEAGIEYTIRQIDEYRALGVNGIHLYALNKWKDVSEIIDRCG
LRTLV
>A0A0B1U1N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp. TomC|TrEMBL
MEARRPFVSLEFFPPKEREAWEGFFGVVERLLPVRPLFVSVTYGAGGSTHAHTLEIVSRL
KTAYGLEPMAHLTCVGASQDKIRGFLDALRAAGVDNVLALRGDPPKGQEHFVPDSEDFQH
ASDLVTFIRQEYPELCVGVAGYPECHPEAASPEADLEHLRAKLARGGNFVVTQLFFDNDK
YFAFVDKARAAGITAPMVPGVLPVLSLGSIKRFASLCGASLPPAYMAELEAADAAGGAAA
VAEVGIEYARNQARDLIARGAPGVHLYTLNKAEAVLSIVSGLEY
>W1WVS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli DORA_A_5_14_21|TrEMBL
MMTLREKHKQGKFTITVELDPPKSSSAQKVFDQAARLKGKVDAINIADSPMSKMRMSPIS
LSYLLQHNEGIETIFHLTCRDRNIIGLQSEL
>A0A3S6F0L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia entomophaga|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKDIKERTGLDAAPHLTCIDASAGELREIAQDYWRNGIRHIVALRGD
LPEGSGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMTSVFE
GLDNDPETRKMLGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRP
>A0A2A2SHN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas lenta|TrEMBL
MTLSVPQLEEARRALDAPLFADLAGDMAVSFEFFPPKNEKMEETLWSSIRTLEPLGPRFV
SVTYGAGGSTRERTHATVARIQRETPMAAAAHLTCVEATREEIDAVANEYWAAGVRHIVA
LRGDSPTPGTPYATHPGGYENAADLVAGLRKLHPFEISVAAYPERHPDSPCDQSDIDNLK
RKIDAGANRAITQFFFSPETYFRFRDRAVAAGVDAEIVPGILPVMSVAQVRKFAGQCGAS
IPDWMDRLFEGLDDHPAARQLVSATIAAELCRKLYAGGVREFHFYTLNRAELAYAICHLL
GVRPKAVAQAEAA
>A0A077JE63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|cyanobacterium endosymbiont of Epithemia turgida isolate EtSB Lake Yunoko|TrEMBL
MINRFRQAVQNKEFLITAEVTPPKGSNPARMVEMAQKLKGRVHGVNVTDGSRAVLRMSSI
AASALLLQYGIEPICQIACRDRNVIGLQADLMGAYALGLRNVLALTGDPVNAGDHKKAKA
VFELESVRLLKMINNLNRGVDFNYQSLPDDSLDLFAGAAVDPQCPSWSGLQRRFEHKLAA
GAQFFQSQLITDFEQLDKFMHKIAAGTGKPILAGIFLLKSAKNANFINRNVPGVKIPETI
IQRLANANDVLQEGVKIAAEQVQLAKELCQGVHVMAVKREDLIPKILNLAGVSPISLEQA
IIN
>A0A520I0A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKIIDHINNAEGKTLFSFELLPPIKGQSIQGIFNAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNRYKVDAVPHLLCGGFTKDETENALIDMQFLGIDN
VLLLRGDARKSDSSFIPTPDGHAYASELVSHVANMNRGQYLHDDLANEKTDFCIGVAGYP
EKHFESPNLDTDFKYLKHKVDLGAEFIVTQMFFDNNAFATFVEKCRSNGITVPIIPGLKP
ITSSKQLVSLPKVFHLDIPLELTEAIQACNSEKEVKEVGIEWMINQCKELKSMGAPVLHF
YTMGNPEPTKKIAQAIF
>A0A084TM42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mangrovimonas yunxiaonensis|TrEMBL
MKVTEHIKQANGKTLFSFEIIPPQKGSSIKELYNKIDPLMEFKPPFIDVTTSREQHVYIE
KNGLLDRKITRMRPGTVGICASIKHKYHVDTVPHVLCGGFTKEETEYLLVDCHYLGIENV
MALRGDAMSHQKYFQPSQGGHSYASQLVGQIQNLNKGKYLHEVIDAGDKSDFCIGVAGYP
EKHIEAPSLKSDLKRLKEKVDAGADYVVTQMFFDKKKFFEFVTAAKQAGINVPIIPGIKP
IATKKHLQLLPQVFKIDLPEALIEAVESCKDNKAVRQVGVEWCIAQSKELLAAGVPVLHY
YSMGKSDNIKAIASELF
>A0A1G1Q357|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium RIFCSPLOWO2_12_FULL_63_16|TrEMBL
MNLPEGERFERKLGAKSFLVTMEVNPPKGTDLSEIEAAVERVKGLVDAINVTDGSGAIMR
ACSLAVAKTVLDAGVDPILQMTCRDRNRLALQADVLGAHILGIRNVLLLTGDDPKAGDHP
EAKPVFDITSAALMQAARGLTQGHDMAGKELRGAPRLCLGAAADPGANDLDVEMQKFKAK
IDGGAQFFQTQAVFDIETLRRFMDRARGFGNAASPAAGGTSSVGSPAAVDTPSPERIVPA
RSPAGTVPARSPVLAGLLLVKSAKMARYMNEHVWGIHVPEELINRFERSGDARRECVAVA
AQLLNELRGVADGVHLYALGWDDLVPEILKKAGVR
>A0A519UJQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKITQHIAEAKKTLFSFELLPPIKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKEQ
ENGLLEKVSYRKRPGTIAICAAIIHK
>A0A5B0C979|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ANT_H4|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLHSLLTQYKSAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRFIRKQLESYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>H5XTQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus youngiae DSM 17734|TrEMBL
MENKFKESLLDKNTLSVTWELVPGRGANEKAQQTAIASAEQAAKGGRIHALTITDNPGGN
PAILADYLGMEILKLGIEPLVHFTCKDKNRNQMESQLYALDRAKVRNLLVMTGDYTYSGF
KGRPKPVFDLDPSNTLQLITEMNKGLEVPGMKGPTYHAPSDFFAGAAVSPFKSTEAEQMI
QYYKLKKKIQGGAQFIVTQLGYDARKCHEVLQFLKVNKLDVPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNEEKTAADKGVGQRMLRAAKMYAFMKGMGFAGVHIGGHNLKYEQ
VEYIIDKGEELSANWQDYIKEFDYPQNNGFYYFEKDEKTGLNTDRPANRKGRPLDAPAGA
MNSLMRGMHSLMFTPNKKLFPVLRSMYHAAEGKKKAEKRLHAVEHIAKVVMLDCKDCGDC
AILDIGYLCPMSQCPKNQRNGACGGSLDGWCEVFPKEKKCVWVRAYARLKKYGEEHTLDV
PPVPPANWDLYQTSSWSNFYLGKDHSAPILGIKRPESKIKK
>A0A2N8G7N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FW305-130|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSTERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALAAFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQLARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQPTPLPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
VFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQTQVHTLEQWAPA
WQASWQMPGLPAVIFHPPQAAWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRRPLWATRVGAQVLHKVERAVKRPWVGCDTCGRCRLEDTLYVCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFQAATP
RRVSPQPAPRSQPES
>A0A7X0AEB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. MP1X3|TrEMBL
MPAISFEFFPPKTDEQRAQMDRAAQLLKAHQPEYASVTFGAGGSTLSYTSETVQHLNKVH
GLSVAPHLSCVGGTRAELGALLDEYRAAGYRRIVALRGDLPSGMATPGDFRYAVELVAFI
RQHSGDHFHIEVAAYPETHPQADNALKDLQHFKAKVDAGADGAITQYFFNADAYFRFIDD
AGKLGVNVPIVPGIMPIANYSQLRRFSEMCGAEIPRWIAKRMQAHGDDAESVRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRAKATQSVLQQLV
>A0A7J9I6K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium harknessii|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDIRPIFWSNRPKSYITRTIGWDQFPHGRWGDSRNPS
YGALTDHQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSYCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCPKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGTTDVNAVTWGVFPAKEIIQPTVVDPASFMVWKD
EAFEIWSRAWAALYAEGDPSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>R4LAA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes sp. N902-109|TrEMBL
MALGLPSRLPATPAIGSLIRRPGPTFSFEFMPPKTREAEQLLWQTIRELEPLQPDFVSIT
YGAGGSTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRNVIGRLAAAGVRNVLAVRG
DPPGDPNGEWVRHPEGVLYAEDLVRLLREVGDFSVGVAAFPYKHPRSGDVESDTRNFIRK
CRAGADFAITQMFFEADDYLRLRDRVAAAGCDTPIVPGVMPVLRMATIARSAQLSGAPFP
PALLARFEQVQDDPDAVRRLGIDLCSEMCQRLLDEGVPGIHFITMNRSTATREVWQHLAD
RAAAA
>A0A8H8X446|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMFAADLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>W7L4S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus firmus DS1|TrEMBL
MSFLNKLKNEIIIADGAMGTLLYSYGTDSCFEELNLSQSEQIQHIHEAYVGAGAELIQTN
TYAANYLKLQRYGLEDSVKEINSAAARIAKKAAKGRAYVAGTIGGIRGFKPNMITLEEIK
RSFREQLYCLLLENVDGILLETYYDLEELETVLAIARKETDLPIIAQVSLQEAGVLQNQT
PIADALKKLDGIGADVVGINCRLGPHHMLKTLESVPLPEHAYLSAYPNASIPAYTDGKFH
YEGDAEYFRQSAIEFRNQGVRLLGGCCGTTPDHIKAFSDVLKGLPPIEEKETKAINKIIV
SEKPSSSRELPPLQDIVRERPSVIVELDPPRKLDTSRFFEGAKALKEAGIDSITLADNSL
ASPRVCNSALGYLVKQQTGLRPLVHVTCRDRNIIGLQSHLMGLHALGLNDILAVTGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSFSGKDLGQKAAFSVAGAFNPNVRSLEKAVG
RLEKKIEHGADYFISQPVFSEEKLLEVHEAVKDLKAPVYIGLMPLTGSRNAEFLHNEVPG
IKISDSIRNRMASLKDDPARAGAEGIAIAKSLIDTAAELFNGIYLITPFMRYEMTVELSN
YARETTERLSRRKQHA
>A0A2N7Q856|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MKVTEKIKKGPILSLEILPPDRGKNLEEIFQILDRLLKFPVDFISVTKHPPEITYLELPD
KIIKVPKVKRPGSIGITAALLNKCRLEVIPHVLCYGMSKYELEDMLIDLHLLGVRNVFIV
RGEYENHQPVEVQDEYQHAEELVRQVAGLNRGEYLYPCENAQPTDFCIGVAGYPEKHPES
PNPTEDLKQLRTKVEAGADFIFTQMVFDFEIYQTFIERAAAFSIKVPIIPGIKPIISLKT
VYNLPRKFFVNIPEELVNQLQEARTPEMEFKVGTKYMAELVQKLLDSGAPGVHVFTMGKG
QGTQALLQALYGKEI
>F2NGM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2)|TrEMBL
MSVKTPSTLEKILASGQQAVTSEIGPPRSTDGAEIEHKANLIKDYVDAINVTDNQTSVVR
LCSLAACIRLKQMGLEPVMQMTTRDRNRIAIQSDILGAASFGINNILCLTGDHQIFGDHA
ASANVFDLDSVQLLETVRLMRDEGKLMSGFDLPSRPNMFVGAAENPFAGPNVLVRAMRLA
KKIKAGAEFIQTQCIYNIPKFKEWLKIAVDKGLTQKVHILAGITPFKSLGMARYMKSRVP
GMDVPDNLIERLKGVPKEKQAEEGIRLAIEMMQELKGLNGVKGFHIMAIEWEEKVPELVK
GAGLYPRPTA
>A0A0M1I300|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. C15|TrEMBL
MTKRVPISFEFFPPKTDIGAEKLITVHQDLQQLQPEFFSITYGAGGSTRERTLAAIKEFN
GKGTPVAPHLSCIGDDKARIAELLDLYVAQGINKIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAETFDQDIQRFTEKVNAGANSAITQFFFNPDAYFYFL
DRLQKQGITIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSRSIRAFGHE
VILKLCERLIDGGAPSLHFYTMNTTEPTRQLVVDLGLN
>A0A1S7PBR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium tumefaciens str. CFBP 5621|TrEMBL
MHKLPDISAASIIPASIEASPAQVLGASDLAGLFPQGVRVYLTDTGAASQERLVDAAGHL
RDLGYEPVPHLAARRIASRTGFEEQVRRLAGEAGVTDVLVVGGGVDRPAGPFASSMDMLS
SGIFDRCGIRQIAIAGHPEGSPDFNDDTAMAALRLKRDFAERSDAAMRIVTQFGFDPARF
IAWAEGLKASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTTLAKGHS
PESIVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGGADRSASQDSIAG
>A0A0B2WNM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium album (strain ARSEF 1941)|TrEMBL
MDKITDKIAALPADREYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSKRLVDKALEDAKALGIRNILALRGDPPRREE
YRDAQDSDDDGQEDFTYAIDLVRFIRKKYGDYFCIGVAAYPEGHSDESHPRVQSLEHDLP
YLVDKVQAGADFIMTQLFFDISAYDHFEKTLREHPSGAFKTIPIMPGLMPIQSYHMIKRT
TKLSHAKMPTAIMDRLDAFKGDDEKVKSVGVDIIGELIEQIRTIKSRTPGRRGFHFYTLN
LEKAVSFIVERTGLIPDESEHEEVLIDDNALAPPAIQVNGARTSTHSRTSRRQSSVGSDP
YNRVIVAGQPPTHPEWEATGQEAGVPAESINSRANTLAISEGEGVLGREATWDDFPNGRF
GDSRSPAYGEIDGYGVTLHMSVSQAVTLWGRPTSRQDVNDVFVRHIKGEIAAMPWSEEGL
SPESSTIQTQLIEMNRRGWLTVASQPAVNGVSSSDRTFGWGPVNGFVFQKAFAEFFLPSA
DWRVLEDKLKGSDHLDSVCFYAANAKGDFVSSDTSGGASTRTVAASTNAVTWGVFPGKEI
VTPTIIEEVSFKAWSEEAFGLWGEWANVYGRGSESHKVLAGIRSDYWLVNIIHHDFIDGE
ALWRLLLC
>A0A1T5JR20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas indica|TrEMBL
MTDVSAATSIPLSFEFYPPKTDEQRQQLDRTAEKLKAYSPEYVSCTFGAGGSTLSYTSET
VRHLNQQHGFSAAPHLSCVGGSREEIRELLKLYRAIGCKRIVALRGDLPSGMGHPGDLRY
ASELIAFIRQEHGDTFHIEVGCYPESHPQSEDAMSDLKYFKAKVDAGADGAISQYFYNAD
AYFHFVDGARKLGVEIPIVPGIMPISNFSQLKRFSEACGAEIPRWINKRMQAYGDDAESI
REFGADVVAKLCEQLIAGGAPALHFYTLNLAKPTQTILARLGV
>B1VZV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A2T4MH94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus agnetis|TrEMBL
MSRLLNTLKDNILVADGAMGTILYSEGLDTCPEAYNLTHPEKVEHIHRSYIQAGADIIQT
NTYGANFEKLKAFGLEHKVRDIHEAAVAIAKRAAKEDTFILGTVGGFRGIKQGDFSLPAI
QYHTEIQVDSLVQGGVDGLLFETYYDLDELLTVIKATRKKYNIPIIAQLTASNTNYLRDG
TVINDALEQVIQAGANIVGLNCHHGPHHMKNTFSHIALPSHAYLSCYPNASLLDIENNNF
KYSNNATYFGEVAEQLIQEGVRIIGGCCGTTPEHIHHIKTSVQGLKPIKHKKVIPIHKKQ
ESMQHPSSKLNLKERVTRQPTIIVELDTPKHLDTGRFFKNIEALDRANIDAVTLADNSLA
TVRISNVAAASLIKQKYHIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNEGINTDGDALKRRTNFNIAGGFDPHVRNIDAAVRK
LETKIESGMHYFITQPVFTKEKIVEIYEATKHLNVPLFIGIMPITSYNNALFLHNEVPGI
KMTDDVLARFKAVAGDKTATYELSISICKSLIDTVHQYFNGLYLITPFERVDYSLELAAY
SKSITSTNQEVIL
>A0A1M6U3S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hespellia stercorisuis DSM 15480|TrEMBL
MKTVDLFGKKTVLSYEVFPPKATSSINKIYETLDELQMLNPDFISVTYGAGGGGNAHKTF
RLASMIKEYGVESVAHLSCISSTKEEIEEALVELKKNGVENILALRGDIPSEGYAPGDFK
YASDLIAFIKSHGDFNIIAACYPEGHIEAKSRVEDIQNLKIKVDAGVDQLITQLFFRNED
FYSFSERCQLAGINVPIEAGIMPVTNKKQIERMATLCGVNVPKKFVTMMDRYGDDPIAMR
DAGIAYAVNQIVDLIAHGVDGIHLYTMNNPYIARKIYEAIHRLI
>A0A1H1BU52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas sp. CF125|TrEMBL
MRTPVSFEFYPPKTDEQRSQLDRTAEKLKAHSPEYVSCTFGAGGSTLSYTSETVRHLNQT
HGFDAAPHLSCVGGSREEIRELLRLYRALGCKRIVALRGDLPSGMGHPGDLRYASELIEF
IRAEHGDAFHIEVGAYPETHPQSDDALTDLKHFKAKVDAGADGAITQYFYNADAYFHFVD
AVRKLGVRIPIIPGIMPISNYTQLKRFSEACGAEIPRWIGKRMQALGDDADGIREFGADV
VAGLCQRLIAGGAPALHFYTLNLAKPTQSVLSRLD
>E2N7K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides cellulosilyticus DSM 14838|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYDTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELAYEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A4T0USY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. GY 10127|TrEMBL
MTLASRVAQREGELLLFALTPPRTTTDPERAQEIADLTRERLSPLDLDGLVLYDIDDESD
RNPAERPFPFLPTMDPAQFSSRHLAGWDLPVVVYRAVGKYEEDDLRTWLGAQDAEDVLTV
FVGASSKDKRTATSLARAQELRAQTRPDLLLGGVAIAERHTRRGTEHERLLAKQEAGCSF
FVTQVVYDVNAAKNLVSDYHYACLERGVEPVPLVFTFSVCGSLRTLEFLGWLGVDVPQWI
RNDLRHALDTLEASYQHALGAARELIAFCRHLGVPFGVNVESVSIRRAEIEASVELARQL
AGELRR
>A0A3N9MYR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MKVTEHLDKAKNPLISFEIIPPKRGGDIQGLLKAVDDVSKYNPPFIDITSHAAVELYSET
PEGIKRKVIRKRPGTLGICALIQNKYKIDAVPHILCRGFTREETEDFLIELQYLQIENVL
AIRGDDSGYEKPLPRGRSANKDARELVRQINNMNNGRYLEENLIDAHSSDFCIGVAAYPE
KHFEAPNLDFDIRFLKEKIEAGADYIVTQMFFDNRVFFDFQDKCRKAGIKVPIIPGLKIV
SHKNQLNNIPRHFYVDIPAELTDEIMCEKDEHTIEIGVNWSARQVTDLFNNGVPAIHFYI
MQNSSPINMLMKKLNL
>A0A3M1ABE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MIKHHLQIKPVRRPRDRRPKLLEIVKQRPTFIVELDPPRDLQFEKIIAGARELKACGADA
ITMADSSLGITRMSNMALGHLVQDRTGLLPILHMSCRDRNLIGIQAELMGMYALGINYVL
AITGDPAKFGDQPGATSVYDLNSFNLVRMIKQMNRGVSFSGRAMGQGTHFTVGVAFNPNV
ARIETQVRRLRKKLKYGADFVMTQPIYRPEQAKELARVAREFDIPFFVGIMPLVSARNAE
FLHNEVPGIEIPGKVRERMRKFEGEKAREEGIRIAHEIEQEVLAYFNGIYLITPFKRHEM
CVQLIELARPVAKLNYS
>A0A4U5X169|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces galbus|TrEMBL
MDVVAPLPRPAAGDLLDGFSLEMTGKDVAALEAARPAIPDGTRVNVTFLGTEDTELRLAA
VRAVRRLGLVPVPHLSARRLRSRAELDAFLSALRDADAADHVFVVGGDPSVPLGPYDDAL
AVLRSGLLQEYGVRHVGVSGYPEGHPAISEPVLWSAIEEKAAVLREEGLTGSVITQFGFD
TEPVLAWVEAARDRGVDLPVRVGVPGPAGIRRLLRYAARFGVGTSAGIAKKYGFSLTNLM
GTAGPDRFVRALAERHDPGRHGELGLHFYTFGGIGATSDWAAAFRTGTHVPAPAPASA
>A0A2L0LVG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. PONIH3|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALLAEYQAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGNHFHLEVAAYPEMHPQARNFESDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITHMCEQLLQGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A1E7HHU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium S3730MH12|TrEMBL
MKLKDALKKNQFIVTSEVQSPVEDDPEKLIQNLQLIRGRVDGVSVSEIEIDGVVGDTIKT
CDLLKKSNFDPIYQTTTRQKNRLQLQKDLIGAHEAGIENLLVFTEDYRLTGDSLQEMMFF
HVDAGKLSSVLDHLKEGHTVEGDALPEKTEFLLGSGVESSWGKNIPDLEMREMEEMTKIG
TGYFLTTPVFNLDSFEKFIKNVNTFGVPVIAEVLIIRTAGMGQFLNRHMKPGLVPDWVIK
KLSQAPEKQKASIEIFADIVSGLKDICQGVHIISIGGEQRLRQYLDAAKLK
>A0A0N0D1A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Magnetomorum sp. HK-1|TrEMBL
MKSGSNLEKILRSGNFAFTGELGPPRGANVDAVRKKAEPLKGMVDSVNITDNQTAMVRMS
SWAASIIAIQEGLEPNYQMVCRDRNRLAMQADILGAYAHGIRNLLCLSGDHQQFGDHPNA
KGVFDIDSIQLVNMLKNMRDEGKFMGGANIDTPPGMFIGAAANPFADPFEWRVHRLAKKV
MAGADFVQTQCIYNMKKMREWVKQANDMGLTDKIYILAGVTPMKSLGMARYMKAKVPGMD
VPDEIINRLKGVKKNVQADEGIKIACEQIEEFKEMKGVAGVHLMAIEWEHRVPEIAERAK
VLPRPVIKDEDVS
>A0A4Y3R3S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cacaoi|TrEMBL
MAIGISAPRTDRPPAVRELLASGKQSFSFEFFAPKTEKGERTLWDALRRIEAVSPTFVSV
TYGAGGSSREGTVRNTERIATETTLTPVAHLTAVNHSRTELRNVIGQYADAGIRNVLAVR
GDPPGDPLGEWVPHPQGLRYASELVELIKESGDFCVGVAAFPEMHPRSSDWETDVRHFVN
KCRAGADYAITQMFFRTEDYLRLRDKAAAAGCETPIIPEIMPVTNVGQIERFAQLSNATI
PPELIDRLRAVEDDPKAVRSVGIEYATEMCTRLMAEGVPGLHFITLNHSTATLEIHQNLG
LHPRP
>A0A850I6B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. 2S1|TrEMBL
MTETISSVPNGYRAPKTPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTITRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAAIKRRHADIEISVSAYPEKHPEAADFDADIDTLKAKVDAGA
ARAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A358GRW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp|TrEMBL
MKADLRSVMRERVLIGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
HETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGANGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGASPEYFGQTAVQFADLGARIIGGCCGTTPDHISAIAKALVEYTPVPILEPDPSE
SKPRIILHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVSFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
SMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A370AXI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanispirochaeta sp. M1|TrEMBL
MTPFLEQIKKQPLVFDGAMGTMLYSKGIFLNRCYDELNITNPEIVAEVHKAYSEAGADVL
ETNTFGANRIKLTEHGLGDKVVEINKAAARLAREYADEAQYVAGSMGPCLKSGQILKENR
REELAAVFTEQAEALYKGGVDLIILETFSHSEELILAARCAASTELPVCGCFTLTEEGYT
PGGENLETLMQKLNDCDALDVLGLNCGTGPSHTYNWVEKAVTLTDKPIIAMPNAGFPKQK
DDRMVYLTNPEYFASYAKKFIELGVSGIGGCCGTTPEHILKASRTVKATSLVKQHVEIKA
VDKESIEITPVPQEQKSRLACLLKQGKMVTSVELTPPRSTDLTIFINKAKICAFHGVDAI
NIPDGPRASARVSPMIAASIIQKEAGIEAVLHYTCRDRNLLGMQSDILGSVAAGLNNFLV
ITGDPPKSGDYPEVTGVFDVDSIGLTQVVHNLNYGRDFGGNPITPPTAIFTGVGANPCAV
SPELEMDRYRRKIEAGAEYAITQPVFDPDALLRFLDKASAFGSIPVIAGVWPLVSFKNAE
FMRNEVPGVEVPDEVMERMSRCKTREEGIAEGIRIAEDICRIIEPHVQGFQVSAPFGKVE
LALKVLGMDTNK
>A0A1J4TU11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium CG1_02_37_35|TrEMBL
MKSFRERLGNELILFDGGTGTYLYEKGIYINRCFDELNLTNPELVTEVHCDYINAGADII
ETNTFGANSFKLTPHGLGNKVYEINLRGAKLAKTAAKESVLVAGAVGPLGVQIEPLGKLS
FDEAKDVFKEQIKGLLDGGVDLIVLETFALVKELIQAIRAVRELNADIPIVAQVTINESG
TLLSGAPLERFIEKLKDYPVDAVGLNCSVGPKAMLDALENLRSLTDIPISVQPNAGLPQN
ISGRNIYMTSPEYMAEYAKRFIQTGANIVGGCCGTNPTHIKAMRKAVQALQPVKKMDVKI
ADLQVEKPSEIKIYEKNEKSRLSNKLLKKEFVKLVELVSPKGVSPSREVDKARKLYHAGI
DAINIPDGPRASARMSALALAAIIQKEVGIETVLHIACRDRNVIGMQSDLLGAWALGLRN
ILAITGDPPKLGNYPDATAVFDVDAIGLTNIINRLNHGLDIASNPIGDPTGFCVGVGVNP
GAINLDEELKRLEWKIEAGAEFMITQPVFDIKLLEHFMKRIEKIKLPLICGIWPLVSFRN
AEFMNNEVPGASVPQKILQRMKKMTTKEEGFNEGVKIARETFDQVKTFADGVQISAPLGR
IEAIFDMIE
>A0A7C2AKQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon|TrEMBL
VFNLNRFQEWVDTIRSLGLDKKVHILAGVTPLKSIKMMQRMRFHVPGVDIPDEIANRIEN
ARDPKEEGYNIAIEILEELKKINGIHGVHITALFWEDIIPKLVKEVNLYPRP
>A0A6P0YNZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Merismopedia sp. SIO2A8|TrEMBL
MTTINDLPISFEFFPPKTPEGVEKLHQQHDRLCQCNPDFFSVTYGAGGSTRDRTQRLVFD
LNPKGIPTVPHLSCVGDTRESLTRLLDSYQASGVRAIVALRGDRPSDDDKIAHEFYYANE
LVEFIRQQYGDTFELFVAAYPEVHPEATTAHQDLTNFKRKVDAGATAAITQYFYNPDAYE
DFINRCQQQGITIPIFPGIMPIT
>A0A1H3BCJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tritonibacter mobilis|TrEMBL
MTTPEISFEFFPPKNLEASFRLWDTVQSLAPLAPRFVSVTYGAGGTTRELTRDAVTTLHK
NSGLKVAAHLTCVSATRQETLDIADQYAAAGITDIVALRGDPPKEQGRFTPTEDGFGSSV
ELIEALAAKGKFNLRVGAYPESHPEAASQQANVEWLKRKLDAGADEALTQFFFEAESFFR
FRDACAKAGIDTDRITPGILPIENWKGVRRFAEACGTTIPAWLDEAFEKAQRDDRCDLLA
TALCSELCTELLDGGVKKLHFYTLNRPELTRDVCHALGVKSKARLQNVA
>A0A1D2QPK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Endobugula sertula|TrEMBL
MNSSEFRLSFEFFPPRTEAGKEKLVHVRNQLHQLSPEFFSMTYGAGGSTRNNTKALVIEY
NEAGFPTVPHLSFGGDTEETIIALINAYKNSGVNRIVALRGDMPSGMGSASQMVYANQLV
AFIRKHFGNDFHLEVAAYPEIHPESASYTTDVHYLKGKFDAGADSAITQYFFNLDAYCFF
VDQCQRAGITQPIYPGIMPIIKMQNLVRFSETCGAEIPRWLCKAIEAYGDNQESMMAFGI
DVVTELCEGLIDQGIPGLHFYTMNQIEPVKSIIDNLGLSSRAFK
>A0A179DBW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter psychrophilus|TrEMBL
MKITDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIDPLMEFKPPFIDVTSLREDYIYKE
KESGLLEKVSYRKRPGTIAICAAIINKYGVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADSSFVPTKGGHCYATDLIKHIKDHNSGKFLHEDVVSDYNSDFCIGVAGY
PEKHFEAPNLKADFKFLKQKVDAGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLK
PISALGQLVALPKIFHIDLPEELSEAVQECTNVKDVKKVGTEFMIQQCKELMDFGVPVLH
FYTMGKPEQTYNIAKAIF
>A0A4R8BV04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2573|TrEMBL
MRGFELVCEVEPPTRPDLKRVRHQIGVMSPIADGFLIPDNHIGRATVSSVAVANEVQLMG
ARGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDEPAEGARTSQLTVRTMIEQARD
TTYPGCNPFQVGAATRLTKVPRWKAEADFLYVQVSYDLDELLRWRDSVDLGIPVYAGVMV
LASAKMAHDLAALPQLKIPPALIEAVDQDRDAGVDHACEQILAIRDSGAFDGVHLIPVSR
YRQVAARLEREL
>A0A2H0M0H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG11_big_fil_rev_8_21_14_0_20_41_12|TrEMBL
MTFKEKIQAGKFLITSELGPDKGIQTQGLLDDAELIRNKVDALNVTDLQSSVMRLGSLAV
SIMLKQKGFEPIYQLTCRDRNRLALQSDLLSAAAFGIENVLIVTGDHPTLGDHPQAKLVF
DLDSVQLLQVAGKLATGHDMNGNKLTGAPPRFCLGAVVNPGSDPLEPQIMKMDKKVSAGA
EFFQTQAVFDLKTFENFISKIKYIKIPVIAGIVLLKSAEMANYMNKNVPGISVPDNLIKE
MNNSKDKTATSVQIAAGLIKELKPLCRGIHIMSIGWGKIVPQVLQASGL
>A0A419AQF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium carotovorum|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLRDIAQDYWQSGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTTMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>K6WXG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineosphaera limosa NBRC 100340|TrEMBL
MSNALPSTVLERLLHGARYEVLPTATIAEKVLTHVPRTTTVTVTASPSKPLSTTLDMAEQ
FAAEGFDVVPHIAARMVSGRTELSEIVDRLRAAGITKVFVPAGDAADAAGDYTGAIDLLT
DLHALDHPFTHIGITGYPESHPSIDDDVTIQSMWDKRKYATHVISNMTFDAEAVGKWSER
MRRRGIALPIVVGVPGPVDPTKLLGMATKIGVGDSVRFLRKQRGVFARLAAPGFTSDRFV
TRIAALAATPQLAIEGLHIYTFNQVEAIEAWRQKMIAEAQRR
>A0A4U1MFV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus hwajinpoensis|TrEMBL
MSLLSELENNVLIGDGAMGTLLYSYGIHQCFEELNLSHPEQVLNIHRAYIDAGSDVIQTN
TYGANYSKLVRYGLEDFVKEINTEAVKLARKASKESTYILGTIGGIRGINTRATALDEVK
RSFREQLYCLLLEGVDGIMLETYYDLEELTTVLEIARKHTNLPLIAQVSMHEPGVLQDGT
SLSSALKQLETAGADVTGVNCRLGPYHMIQSLEQVPLSQSFLSAYPNASLPDYEDGRLVY
PTAPDYFRESALALHQQGARLIGGCCGTTPEYIAAAASALKGIKPITSKEVTVKDNDSFI
FESESDRLPHLHEIAYYQKSIIVELDPPKKLSIDKYLKGAKALQDIGVDAITLADNSLAS
PRICNTAMASTIQTQYNVRPLVHIACRDRNIIGLQSHLMGLHTLGINQVLAVTGDPTKIG
DFPGATSVYDVSSFDLIKLIKQFNKGLSYSGKSLGIKTSFSVAAAFNPNIRHLDRAVSRL
EKKQQYGADYFISQPIFSEEQLVEVYEATKHLTCPIYIGIMPLTSSRNAEFLHNEVPGIK
LSDTIRNRMAKASDQQEAQNEGLAIAKSLIDAAFDLFNGLYLITPFLRYELTVELARYIK
EKTRLEDERKIRNGLHIV
>A0A7C1V226|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
MKVIDQIKSATETVFSFELLPPVKGHSIQKLYDAIDPLMKFNPININITYHQQEIVYKKL
KQNLVEKTIIKKRPGTVAVSAAIKYKYNITVVPHLICGGFTKEQTESGLMDLHYLGMHNV
LALRGDPPRGEKRFAPEEDGHSQAAGLVGQIVNMNKGIYLDENLINATPTDFSVAVAGYP
EKHFEAPNMKSDLVYLKEKVDAGADYVVTQMFFDNKKFFEFVDLCRAEGITVPIVPGIKP
ITFLNDLRLLPQTFSIELPDDLVRELKKCKETAEARQVGVEWGIQQSKELKAAGVPVIHY
YSLGLSENIRQIVSAVF
>A0A158NKS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atta cephalotes|TrEMBL
MRNLILENDICERNDADGNDNSSISDFHIENPHKTIVNLRQLLKDKISKNEIFYSFEIVS
TRKSGVFYRRFLIDMEEYSPLFYALTWHNEATSNNDGYLPLDLAENFPANTLLHLTAKGL
KRDEVIYILKKALAFGIINIFALRGDSLSENGDFEHAADLVVFIRQRFGDTFCVCVAGYP
QMHPESSSKELDLHYLKAKVEAGADFIITQICFDSRVLINFVRDCREIGIQIPILLGILI
PTNHACLEKMIDKCRLDVPIKIKEELARMKDDDQAVRKYSVDLIAQIITDVIRNGATYGF
HLFTLNRLSLVAEICKHIESFKAEKL
>A0A2A4FDW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia ubonensis subsp. mesacidophila|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTGLCQRLLDAGVPGLHFYTLNTAAATRTICERLV
>A0A166KL76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYLDKNQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKSHR
>A0A2T9KAW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter radicis|TrEMBL
MTLPPTRRVIGPVARAGERPVGAARPRVSFEFFPPKTEKMEASLWEAITRLAPLDPAFVS
VTYGAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRAEVDEVIHDYWNIGVRHIVSL
RGDPPPGEGGIGGVYVPREDGYKNATELTAALRGVAPFEVLVGVYPEKHPESPSLDHDIE
VLKAKVDAGATLGISQFFFDIDAFLRFVDKARAAGITIPIVPGVMPVTNFKGLKTMSAAC
QTSVPSWLANLFEGLDEDPETRRLIACSVAAEMCAKLQEQGFNDFHFYTLNRADLVYAIC
RVLGVRETAPAHEAAA
>A0A0S8B2L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium SG8_19|TrEMBL
METEFKSDGRLERVLRSGRFAVTAELNPPDSANPQEVYDAALVLSSVCDAINATDASGAN
CHMSSVAICALLTRAGYAPILQVSCRDRNRIAIQGDVLGAAAMGVCNVLCLTGDDISVGD
QPQAKRVFDFDSIQLLRTIKIMRDEGMFLSGRKLTAPPRLLLGAASNPFVPPYDWRPLRL
AKKVEAGADFVQTQYCYDVPRLRQFLKQVCDMGLDERVYILIGVGPLRSEKAAEYLRTRV
PGVVIPDKIVDRLRKTPKHKKREEGKRICVEIIQQVQEIKCVSGVHLMAYRQEELVAEII
EEAGLLPRPMQPLARDSDPRARPSKRRRANRDGDQ
>A0A4R1JQG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 90|TrEMBL
MKVTEHIENAKGNTLFSFELIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
LMALRGDAMKDEQSFVPKVGGNKFAIDLVRQINDLNCGKYLHEVMDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQIF
>A0A5C8JU08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea sp. C10|TrEMBL
MALGQPSILPGRVPTVRELLASGGRSFSFEFMPPKTDEGQRQLWKAIRELESLRPTFVSV
TYGAGGSSRDRTVDIVERLAHGTTLTPVAHFTAVNHSTRELRHLIGRFADAGVRNILAVR
GDPPGDPTGEWIPHPEGVLYAEDLVRLIRQSGDFCVGVAAFPYKHPRSPSIESDTEYFVR
KCQAGADYAITQMFFRADDYLRLRDRVAARGCDTPIIPCVMPVTQMSTIARSEQLSGAPF
PPEVAARFEKVADDPAAVRALGIEHGAELCQRLLDEGAPGIHFITFNRSSASREVFQRLR
HAPALTV
>A0A351HT97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacterium sp|TrEMBL
MRITELFERGEFVLTAEVGPPKGVELDHLIKDAHEYLKTRVHALNVTDNQSSVMRTGSLA
TCRVLKDEGLLPIFQVTCRDRNRIALQSDILSAALLGIENLLLLTGDYTTLGDHPQAKPV
FDLDSVSLIHAVKRLEEGFDIAGNAVDGAPPKFAKGAVVSPCSDSVDVQLAKMEAKVKAG
CEYFQTQGVYEPEKFIKFMEQAKQFGVPVQLGLIIPKNVGMCRYMNANVAGVHVPDEMIA
ELQADKEKTKAGDTGVEICARLIRECKDYAQGVHIMSLGWENRIPEILDLAGIAPITPVV
>A0A367JHQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus azygosporus|TrEMBL
MKVIDKIKKAEAENRSFWSFEYFPPKTPQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
ELTTEIVATAQSVYGLETMMHLTCTNMPIQQIDDALEAAKKCGCQNILALRGDPPKGQAN
WESCEDGFEHAIDLVRYIRKKYGDYFCIAVAGHPEGHIDNPDKEDDLLRLKEKVDAGADL
VVTQLFFDVDMFIEFYKKARAIGITVPILPGVFPIQNYSGLKRVIAFNDNFVPQKIWDDL
EPIKDDDTAVKEYGINLAVEFIKRFREVGINGFHLYTFNLERSSRLVLERLDLVAPLESI
KPLPWSPSLNTKRAKENVRPIFWKNRTKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
INLRYPVEQCVNMWGTPKSVDDVALTFARYCKGEISGIPWSSQQLDPETDIIRQRLAAIN
LLGYFTINSQPAVNGVKSCHPIYGWGPKNGYVYQKAYLEFFVSPEKLNELIDKISQNPQV
TYYAVNKQGDLRTNTTSDEPNAVTWGVFPGKEIVQPTIVESVAFMAWKDEAFELWNRWAR
IYERDSESAKLILDITDSYYLINIVHNDFQDENGIWRLFDLEIDGEISRKLLQSSVAR
>A0A7C3N4T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLEESLKKKGFVVTSEIQPPMEANATGLLQSVHRIRGKVDALTVPDLKIEGLVADTMGT
CRILKEQNFEPILQTTCREKSRIDIQDLLLRASQTGIENLLTFTEDYRITGDSLQEIMYF
HVDTGKLFSVIEHLQQGQDISGKELPFRAKFCIGSGVDCSWGKKVPDMELREMETLAQLG
THYFLTTPVFDLDSFHQFMRRVGPIQLPVIAEVILVRSPGMGLFLNKYVKPGLVPNHIIE
KLARASDKEQASIEIIRDLVKGLREVCQGVHFVPVGSTERLSKYLEAVEPGISSDP
>A0A7C3S0H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MVAFKERLASGAFSFVVELQPPKGIDLSDFLEQAKGLKNYVEAIYVPDLPNGVMTLGSIA
TCAKLKEAGVETIFELSCSHRNRLALQSELLGASLLGLENAFLRQGESPAIGDHYEAKPV
FDLDGIGLLEVAKGLEEGHDLMGNALKGKPRFFVGSPIEIRSEPKDFDRELREMERKIGL
GAKFFVTTVIYDPRLFEAFVKRAASLHVPVLASLPLLKSAGMARYMSKHVEGALIPEAVI
ERLMKAPDKQKASVEIARETIRELRALCQGIRLIPMGWESLIPLVLDKGGL
>A0A6M0GEQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symploca sp. SIO2E6|TrEMBL
MTKPTYNSFRTAVESGEFLITAEVAPPKGGNPDHMIKMAQTLKGRVHAVNITDGSRAVMR
MSPLAASVILLQHGIEPVCQVACRDRNRIGLQGDLLGAQSLGIR
>A0A1V4EQY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidibacillus ferrooxidans|TrEMBL
MEEKKHPQEIGSANAGRHEPLMARIEREVLIADGAMATQLYQMGTPVGTCYEALCIERPN
AVTSVHRSYLEAGAQLLETNTFGANAYGLARYGLEGKVVEINRAAVRLARNVAGEHAYVA
GTVGSVRGVRPAGPARAELEAIYREQIDALLTEGPDALLFETFYDLDELEIALYVARSLT
ALPTIAQLSLIDLGVTRDGVALSDAFARLYEHGASVVGLNCRFGPSDMLRVLEKARLRET
DRISVFPNAGLLSVTDGAYHYPSEPAYFGEIAQAFHTMGVRILGGCCGTTPEHIRAMART
VAGKAPMPVKVGGQTVSVGVGDAPRSRVTERIDERRDDAQVLVHEKARHDYTVIVELDPP
KDLSPNVFLEGARALSDAGADAVTLADNSLAVTRMSNMALGAMMRQMDIEPLLHMSCRDR
NLIGQQSHLMGLHALGIRQVLAITGDPSRFGDFPGATSVFDVSSFDLIKMIKQLNEGRSF
TGRALDECARFTVGAAFNPHVRHLDKAIRRLERKIEAGADFIMTQPIYDPEFFDVLADLT
AHLNVPIFVGVMPLLSARNAEFLHNEVPGITLTDDVRKRMAEAGTGAHARSVGVEIAREL
VDAAMKRFRGIYLITPMMRYEMTVDLVKHVARVAREVDQAGATPA
>A0A841E426|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella solani|TrEMBL
MDSKPELSGILGGGRRTRLLFYGMTPPRQSMEAAARDRFVEVTRGRLETLDVDALILYDI
DEEAERTPDERPFPFSPTMDPADFLTDHLSWWDRPAIVYRSVGKYAPAELDSWVRRPSDR
LGTVLVGAATSTAPVKTTLPDAYDLWRRGESTLPLGGVTIPERHASRQDEHHRLLRKQQS
GCSFFVTQVVYDVGAAMDLASDYLYLCREQGLEPVPMVFTLSICGSVKTLEFLAWLGVRV
PRWLRNELVHSADPVADSYAHCVAIARTLSAYCHDHGVPFGFNVESVSTRRVENDASIAL
VKELRTFVG
>A0A3A4R295|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MAKSFKEALESGKFVITAEVGPPKGVDIEEMKHHIELLKDKVDGLNVTDNQSSVMRISTL
PVCRLIQEAGGEPILQMTCRDKNRIALQAELLGAYILGIKNVLCLTGDYVTVGDHVDAKP
VFDLDSVLLLKAISGLEQGKDFAGNELKGSPAFCKGAIVTPEANPIEPQLIKFEKKIKAG
AEFIQTQAIYDLDNFKKFMKYARKFDVKIMAGIVLLVSAGMARYMNANVPGIFVPKDLID
EMAGAEKGKALEKGIEIAGRMIKTLKDEKICDGVHIMAIGKEGKVPDILAAAGLI
>A0A7C2VPA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MAFKEALESGKFAVTAEVGPLKGTDTTEIMEVAELLKGKVDGVNVTDQQSAVMRLGSLAT
CHLLVQKGLDPIFQMTCRDRNRIALQSDLLNAHVLGIRNVLAITGDYPTLGDHPDAKAVY
DLDSVQLVWTINRMNQGYDLAGNELEGKTDFFVGAVVTPITDTEAAFELQLIKMEKKVEA
GARFFQTQAVYDVDAFARFMKRAEGFGVPVLAGIIPLKSVGMARYMNKNVAGVFVPE
>A0A7C5YYT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
GIRNILALTGDHPSLGDHPQAKSVFDLDSVSLLHTITQMKNGKDLSGADLVGAPKEIFPG
ASVTPGAEPLEPQLIKMEKKISAGAKFFQTQAIYEPKKFEQFMKQASKFKVPVLAGIVII
KSPAMAKYMNEKVAGVNVPEPIIKKLSEASKEDRAKVAIELMANLMKELKPMCQGFHIMA
MGWEKYVPSLLDQVGLA
>A0A6G2UBA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7805|TrEMBL
MALGTASTRTDHAPTVRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSTAELRNVIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDADVAHFVA
KCRAGADFAITQMFFYPEDYLRLRDRVAAVGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEGVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A853KBF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidibacillus ferrooxidans|TrEMBL
MARIEREVLIADGAMATQLYQMGTPVGTCYEALCIERPNAVTSVHRSYLEAGAQLLETNT
FGANAYGLARYGLEGKVVEINRAAVRLARNVAGEHAYVAGTVGSVRGVRPAGPARAELEA
IYREQIDALLTEGPDALLFETFYDLDELEIALYVARSLTALPTIAQLSLIDLGVTRDGVA
LSDAFARLYEHGASVVGLNCRFGPSDMLRVLEKARLRETDRISVFPNAGLLSVTDGAYHY
PSEPAYFGEIAQAFHTMGVRILGGCCGTTPEHIRAMARTVAGKAPMPVKVGGQTVSVGVG
DAPRSRVTERIDERRDDAQVLVHEKARHDYTVIVELDPPKDLSPNVFLEGARALSDAGAD
AVTLADNSLAVTRMSNMALGAMMRQMDIEPLLHMSCRDRNLIGQQSHLMGLHALGIRQVL
AITGDPSRFGDFPGATSVFDVSSFDLIKMIKQLNEGRSFTGRALDECARFTVGAAFNPHV
RHLDKAIRRLERKIEAGADFIMTQPIYDPEFFDVLADLTAHLNVPIFVGVMPLLSARNAE
FLHNEVPGITLTDNVRKRMAEAGTGAHARSVGVEIARELVDAAMKRFRGIYLITPMMRYE
MTVDLVKHVARVAREVDQAGATPA
>A0A7C2X1G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MFSRIPAPAVTGEIVPNGVQFRPTFPVATTQVAAAGERRRRAVKIRDFFTTDTCVLSFEV
FPPVRDGTIARLVPVIDRLAGLNPHFISVTYGAGGGTRDMSVEIASLLKKKASVEVLAHL
TCVGSGRDQIDEILREFRSEGVQNILALRGDPPAGETSFTRPADGFGHACELVDFIRSYG
WFCVGVAGYPEGHQEAESFEADVDHLKRKVDAGSDFVITQLFYRNEDFYRFRDAAGRAGV
DVPIVPGIFPVINYRQINKIASLCGATIPGELREQIEPVRDNDDEVARRGIDYAVRQTED
LLRHGVPGLHFYSMNRSGPVEEILNNVSVPGRKTA
>A0A318D458|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MISASYAEDKKITQSPNHQITKFPSGSLHSKLQKAMEDRLAQKDSGYDVKGTKRNFVITF
ELVPARASKGKAIDEILQFAKEAAAGGGGGGLISALSITDNAGGHPALTPRALGSEIMAL
GIDPVIHFSCKDKNRNLVESQLFVLDRSGLKNLLVLTGDYPRYGFMGNAKPVFDLDSVQV
LDMISHMNQGFVLDSKAPFGGVKLAPMNFHAGCVVSPFKRLESELIPQYLKLKRKVVAGA
SFVITQMGWDVRKFDELRRFMDREGIRVPLIGTVFIPTTGLAGTLCRGEIPGCILPDRLF
ERIEQEAISDDQEGGPRLERAARLVSILKGIGYEGVHLSGPGLKYSHVRWVIERANEIGE
RWKLFTCQFLFPEEWKFWYFKEDPETWLNCDEPNPGSKASLSLRDSLGLSLGRLFHELAF
EPGKPLFKSLRRMAGWIDGSSSKRHFTSFEYRLKEWLYDCRRCGDCALGEMGFLCPQSQC
SKFLLNGPCGGSRDGWCEVWPGRQRCFYVKVYERLQSLGKQERLGGPRIPPRDWTLDSTS
SWLNFYLGRDHWGIDD
>A0A3N5NGI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEGDRNGPMKDKFVEHLNEKVMLGDGALGTYLFEKGVDLEENTDLLNISDPDLVYSIHE
EYIRAGSELIETNTFGANRFKMLKVGREQRVREINLKGAELACRAAGNEIFVAGSVGPTG
VNFPLENGKIESGTVQNAFVEQMTALLEGGVDLFILETFTHLDELLLAIETAKRIAPDIP
IVAQMVYPFHGRTAIGLDALDCGRASVAAGAAVVGTNCGRGVKAMLSAVERLSYLKDEVF
LSAFPNAGFPEIVEHRMVYSTPPAYMAEKVAEMVKSGVRLIGGCCGTTPAHIHEFRKYLH
IKRHKAIQFVTSVEKSSDLPEGRKDSIGRGGMIESLRSDRIPVLVEVDPPKHLDIEGVLT
GARALADAGADAITLAEHPLAVLRSDNLSLAHRIREETGIQTVLHLTCRDRNILGLQAQI
MGAHVLGLEAILAVTGDPATSTDQPGVS
>A0A7C8DRZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
IQTQCIYNLDRFEAWLSMARDRGLTEKVFILGGVTPLKTAGMAKYMKTRVSGMDIPDEII
RRMEGVPKEKQREEGISICVETITRLKELKGVNGVHIMAIEWEEAVKEIAERAGLLPRPV
FGEG
>A0A6I4U610|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania citrea|TrEMBL
MSPTMDQMREAQRALEAPLFSGLPGDIDVSFEFFPPKNAAMNETLWQSVETLAPLGPRFA
SVTYGAGGSTRERTHQQVVRIQNEARIPAAAHLTCVEATREEVDEVARHYWDEGIRHIVA
LRGDAPDGQSQYAPHPGGYANAVELIAGLKRVADFEISVAAYPEVHPDSPDRQADLDNLK
AKFDAGATRAITQFFFDPQCFFDFRDRAAAAGIDGEIVPGIMPVLSFAAVRRMSGLCGTA
IPPWMEGLFDGLDDRPAARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRAKAGR
>A0A7V4UL16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKAGSNLEKILSKGLFAVTGELGPPKGNDVSVVKRKADLLRGYVDAVNVTDNQTAIVRMS
SIATSSLLIQMGIEPVMQMTTRDRNRIAIQSDIFGATALGIKNMLCLTGDHHTFGNQVDS
KNVHDLDSIQLIDCVRTMRDEGTLLGGEEKIEGKIELFIGAAENPFADPFEFRVVRLAKK
VKAGVDFIQTQCIYDMKRFKEWMKMVRDRGLHEKVHILAGVTPLKSGGMARYMAKNVSGI
IIPEEIIDRIVKAKKPAEEGIKLCVEQIQELREIEGVHGVHIMAIEWEQMVSQITEMAGL
LPRPKVE
>A0A0A7JNZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas parafulva|TrEMBL
MSLLRQALHDHSFVCVMEFVPKPSAKRFAELASIMAREHLCGWPLAVSVGDRVGSALDLS
PLDACQSFETPVPTLLHFSGKDRERQELLAQLPRMDAAGLDQLLVLTGDRLPGHTPGQRP
VRYLESVAALQIVRQARPDWLLGAALNPFKYREEEGGAQYFKAEKKLAAGADFFILQLGF
DFQKYREAQRWMQRQPTPRPLLACVMALTEGRAAMLEHVAGVTVSPAMRRVLAAEAAVSK
AFASQRGIERLALQIIGLRLLGYAGINLSGVHSLEQFVALEQALDTRLAQVQTLDDWQTA
WDQAWQMAGVETVSFHPPGHPWQEGQRGVRASALEQTRYHLLSALHHQVFDRQTLLSRAF
GWGVRQPLWSTPKAARLLHRLERSLKRPLVGCDTCGQCRLQDTLYICPETCPKGLANGPC
GGTQLNRCEFGDRECIHSRKYRTAVTVGQTEVLTQRLIPCVEVGGRQRSSWPRWFAESAT
SVGNEARQELTQG
>A0A7G8HEF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. PROS-U-1|TrEMBL
MRTALQRAIETGDHVVTAEVMPPRGGDPSHMLAMAEILRGCVHAVNVTDGSRAVMRMSSL
ASCKLLLEAGLEPVLQMACRDRNRIALQADLLGAHALGIGNLLCLTGDPVRAGDQADARP
VNEFESVKLLQQVQALNRGVDPVQGTLPDGETTLFAGCAADPQSRSWSGLQRRLQRKQAA
GARFVQTQMVMDPSALERFQHELAGPLDLPVLAGVFLLKSAKNARFINRVVPGACIPDAL
IERLESSENPAMEGVEIAAEQVKRYLGIVRGVHLMAIKAEERIPMILERAGLSSLPG
>A0A5B0FND2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter sp. UC 10|TrEMBL
MTKVTDFIQQANGKTLFSIEIIPPLKGQNINELLNSIEPLMEFKPPFVDVTYHREELIDR
VGTDGIIERVPIRKRPGTVGICARLMERFHVDAVPHVICGGFTKDETEDVLIDLHYLGID
NVLVLRGDPEKSAGVFKPKSGGHTYASELVSQVSDMNKGILLHAETEMFPTNFCIGVAGY
PEKHFDATSFDTDYQHLRKKVELGANYIVTQMFFDNEKYFRFVERCRAEGITVPIIPGLK
PLATRKQLSVLAQIFHLEFPQDLVKEVEKCASDKEVRQVGIEWGIQQCRELIEYGVPVLH
FYTMGKSDNVSQIARQVF
>A0A3R7LIG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylarcula marina|TrEMBL
MAGTICMLRPVYRMLKKEGRMTNLTPPGNASTRPGLLHADISMELPPEMVDGFDPDPGIL
PRGTKIFLTHIAGKDVRAQIHAAKRLLSVGYVPVVHMGAHNFETEEEYVRLVQAHSRNGV
THGLFLGGNPRKHDGPFHEALDLLNHDVLRDANFTHALIGGYPEGHPDIGLDALENARRR
KLEACHARAMSPEIISQFAFDGDAMAAWANRIAAEEPGLPIRLGLAGVTSLPNLIRFAVL
CGVGPSTAVLKKNAGGFMKIMADHDPGGIIEGIETGYFGTNPLNLHFFPFGGWKKTLAWI
GDRRAC
>A0A496Z5B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRPTGGDTNNMARSFEEALTSGKFLIATSLDTPKGMDLEDLARLIKELKDVVDALGVSDN
PHAMMCMSPWAVCRLALEQGVEPIMHVACRDRNRLALQSDLLAAASIGIKNILCVSGDHV
KFGDHIDAKPVHDIDSVHLLTVAKALAEGKDMAGNPLKGSPALFLGATANPEADPLEPQL
IKVDKKIKAGASFLVTHPVFNIENLKRFMNHVKQSKVKVIAGIRLLVPEEASKYKDGSYP
GLLVPDDLIEEIKGADTGKCMKLAGDLIKEIKSANLCDGIHITAPGHEEKIPDIMKAGGL
>A0A0Q7VF27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. Root552|TrEMBL
MNATPTHQRDENPAGPHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RARIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
GAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNGKFLSGRKLTTPPQ
VFLGAAINPFAPPYDFRPHRLGKKIAAGAQFVQSQYCFDVQMFRTYMQRVRDLGYTDKVF
ILCGVGPLASAKTAKWIRSNVPGIHIPDAVVKRLEGAQDQKKEGKQLCIDIINEVKEIPG
VSGIHVMAYRQEEYVAEIVDESGVLKGRKPWKREARSDDQIVAERLDQILHENMTETQVD
MVKSAH
>A0A5B0ELD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paeniglutamicibacter gangotriensis|TrEMBL
MTTDHPGTTSGSLLDGFSLEMTGKDIPALEAAAPSLPPGTPVNVTFLGNEDLSMRVAAAA
AVKRAGLHPVPHISARRLASTGELDSFLEALERVGSAHHVFTVGGDPAEPMGPFSDSLSL
ITSGRLEAFGVNKVSIAGYPDGHSGIEVDVLWSVLEAKVAALRERGLEGEIITQFGFDTV
PILDWLTTLRDRGISLPVRIGVPGPAGIKRLLGYAGRFGVASSAGIAKRYGFSLGNLLGT
AGPERFIEDLARDYQPERHGEIKLHFYTFGGIETTAEWVAAHR
>A0A436ZJG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas koreensis|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A520SQJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|OM182 bacterium|TrEMBL
MSQTDPANTQPSLSFEFFPPRDEDGMAKLLDGAITKLAAFNPDYCSVTYGAGGSTRQGTQ
DLVQAMLATKIQAVPHLSIGGSSDAALYQLVEYYQEIGVTKILCLRGDQPSGDASKPAYA
KDLVERLQQRYPKQFELAVAAYPEVHPDASCATDDLAHFAAKVNAGANSAITQYFYNPEA
YGYFIDRCAQAGLSIPITPGIMPITNIDALQRFSAKAGADIPRWLAKSMSSYANDDKGLI
AFGVEVVTKLCERLLELGAPGLHFYTLNRWGASSQLCRNLGFLER
>A0A661PMZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSYLSDQLAAGKFVVTAEIAPPKGTNLAPALADVKKFEGITAVNVTDNQGANMRLSSLAL
AAQLQRTGTETILQLTCRDRNRMALQSDLLGAATFGIENLLLLSGDHSKFGDHPDARPVF
DLDSVQLLDMTAGLMAGFDMVGQPLNGVPNFFPGAAVNPAAEPFELIFQKVSKKVDSGAR
FFQTQSIFDRASLERFMSAMVPLNVPVIAGVLLIRSGKMARFLNDNIPGVQVPESLLDRF
DRATDPMAEGIAIARETVSWARELCHGVHLMTLGHEDKIPAILE
>A0A661T120|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEKTPSRLEKILRAGHLAVTSECGPPRGSDPEKITRKAEMIRDYVDAINITDNQTSVTR
LCSLAACIHLKGMGLEPVLQMVTRDRNRIALQSDILGAASHDIHNILCLSGDHQLFGDCA
RGQNVFDLDSMQLIQTVRRMRDEGKFLGGDDIDRPPRMFVGAAANPFADPFEIRVPRLAK
KIAAGAEFIQTQCIYNLDKFELWLKQARDRGLHEKVHILAGVTPFKSAGMAKYMKNRVPG
MDVPDEVVKRMSGVPKEKQAQEGIDICVETILRLKEVEGISGFHVMAIEWEEKVPEIVER
AGLYPRPDPG
>A0A2A9P3A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps unilateralis|TrEMBL
MAVDKITNKIAALPDDAEFFSLEFFPPKTAMGFANLRHRLERMEQALRPLFVNVTWGAGG
TTATKSLELAELCQRELGLTTCLHLTCTNMSRRLMDRTLEDAKVLGIRNILALRGDPPRK
EEYREAIGDDDSVEFTWAVDLVRYIRSKHGDYFCIGVAAYPEGHADGSHPEAQSLEHDLP
YLVDKVGAGADFVMTQLFFDTEAYEKFERTLRDHPSGVFGTLPIIPGLMPIQSYQMIKRT
TKLSHARMPDAILARLDAVKGDDERVKKIGVDIVSEMIEQIRAIRRTSSSRRGFHFYTLN
LEKSVSLIVEQTGLIQQDLSDEAVSDSLLSPPPTMHVNGNGPLRQASHSRSSRRQSSVGS
DPHNRVIVGDRPLTNPEWETTGREAGVPADGVNSRANTLAISEGEGVLGREATWDDFPNG
RFGDARSPAYGEIDGYGVSLHMSVAQAERLWGHPAVLEDINRIFVRHIRGELAAIPWSEE
GLMPESSTIQDRLVELNSRGWWTVASQPSTNGAPSSDATLGWGPANGFVFQKAFVELFLP
AGDWRTLLEKLQRPETHDSVCFYAANAKGDFVSSDETRGANDASGTTSTNAVTWGVFPGK
EIVTPTIIEEVSFRAWSEEAFGIWGEWARVYGRGSASEKLLRGIRDDYWLVNVIHHEFVE
KDALWDLLLA
>M3HWL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Copenhageni str. LT2050|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESA
>A0A399EWY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meiothermus luteus|TrEMBL
MKISTLLKHNRPLFSFEFFPPKTPQGEASLFRTLHELKPLKPAFVSITYGAGGSERRKTT
EWAARIQGEVGLTAMAHLTCVGHTREELRAILQGYAEAGIQNVMALRGDPPKGAGGFQPT
EGGFRYASELVAFIREEFGDTFTLAGGAYPEGHPEAVSLEADLHHLKQKVDAGLDFLVTQ
LFFNNALYFGFLERARRIGIEVPILPGLMPITDLAQIRRFMDMCGASIPGPLLSRLERAQ
SPEEVLEIGVEHTTRQAQELLEAGVPGLHLYTLNKSPATRRVMENLQGVLR
>B3LL40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain RM11-1a)|TrEMBL
MSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKT
LALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVE
AGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
AILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETLANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPFKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWET
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKA
WRDEAFSIWSEWAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETDELWEMLLDQA
>A0A660QR37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotogae bacterium|TrEMBL
MKVIEKIKKEQILSIEILPPNRGEDMNQIFSVVENLMDFSPSFVNVTRHAPEVTYVELND
HIKKVPKLKRPGSVGVTAALMNRYNIDVVPHILCTDMNKYQIEDTLIDLHFIGVQNLFVI
RGERENRTVSHVGKDMHSHASELVEQISNMNKGKYLYPCENPRPTDFCIGVAGYPEKHFE
SPNLQEDIRYLKKKIDAGADYVITQMVFDFDVYKRFSEIARESGVLVPIIPGIKPIVNLR
SIYRIPKKFFVTIPETLLSKMHQARTSKEEFEIGTTYMANLAEKLLSEGAPGIHVFTMGK
GRSARALLEKVFGSSR
>A0A661K972|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKAGSRLEKILEAGHFAVTGELGPPRGADAEVIKEKAEHLRGKVDSINVTDNQTSVVRMC
SMAVCKILLEMGLEPNLQMVCRDRNRIAIQSDLLGAYALGIRNVLCLSGDHNKFGDHPQC
KNVFDLDSMQLIATVKRMRDEGKLLSDQELEGGVKFFIGAAANPFGDPFEFRVIRLAKKI
EAGVDFIQTQCIYNMEKFKTWLDQANDEGLTEKCYILAGVTPLKSVGMARYMQKFVPGLD
VPEEYITRLKGVEKKKQAAEGIKICVEQIEQLREMKGIAGIHLMAIEWEHKVPEIVEAAK
LLPRPEVD
>A0A496YV85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGLQERLRSGKFVVLGEFEPPKGADFSPLLRNADLIRGRIDAIVVPEMSNAVLKASSLGG
CAFFQREGIESVFQLCPRDRNRLALQSDILSAAALGIKNIMVVPGQDITHGDHPRARAVY
DLDLLGILEAINKLKNGRDLAGVELRGAVDFCVGTGIDTGAPGGLLTIEMEALKKKMELG
AEFIVTNPVFDLHRLQEFTKRVDTGNIALIPTVLLLKS
>A0A3D3X457|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MQDFDKYIEQDFIQKIIQLSNRCMSDKIPNWSLEILPHHVSEVQGLPQWVEEIYVTMIPG
SKISEVVEASAQLVDEGRTPIPHIAARGMESREQFSEMLESLKQKGVNRLLLIGGGEEEQ
QGPFTEVMDLMETGELQRIGFEEIGIAGHPEGNPSDPDAENSLLKKTRWATKQGISTRIV
TQWCFESQTLNRWINNLHEQGVTNPIHIGIPGPATLKTLLRYAQVCGVKASSEVLKKQGF
NLGKLLFVNKPDRLVQEIRGHQQLHLFPFGGLTKSSEWLQQQRNLASTA
>A0A5A8F0H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus gilardii|TrEMBL
MQDRYYSFEFFPPKTPEGREKLRNTRAQLAPLGPKYISVTFGAGGTTQQGTLDAVLEIQR
DGIDAAPHLSCVGSTREGIREILRTYRDNGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFQIEVAAYPEYHPQARSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRAMGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDREAIRAFGLDV
VTALCERLLAGGVPGLHFYTLNAAGATKAIWQRLKL
>A0A3A4QS18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLREALAKGKFLVTTEIQAPIDEEPEGLVKTFNLVRGRVDGVSVSEVEIEGIVGDTIKT
CEVLRQNRFEAIYQTSTRQKNRLQLQKDLTLAHEAGVENLLVFTEDYRITGDSLQEIMFF
HVDSGKLASVLEHMREGETVDGKELPFKAEFVLGSGVESSWGKNVPELEMKEMEEMTGIG
TGYFLTTLVFDLDRFEKFVKTVETFRVPVIAEVMILRTAGMGRFLNRHFKSGLVPEWIIQ
KLAKASDKQKASIDLFADIVTGIKGICQGIHIITIGGEEKLRYYLDAAKLR
>A0A1A9RJX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eikenella corrodens|TrEMBL
MLHNTLSFEFFPTRTPEGREKQKITRKQLSQYQPEFFSCTSGAGGTTREGTMQTIRDILA
EGMAAAPHIPCVGLDAVELTELLQEYKDLGIRHVVALRGDIPSGMGLGTTGLHHANELVE
LIRHRFGDWFHIEVAAYPEYHPQSRSAEDDIQSFVRKVKAGADSAITQFFFNADAYFRFL
DDVRGRGVEIPIVPGIMPIANFSKLARFADMCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCGRLLRHGAPGLHFYTLNQAGLSSTICQRLGY
>A0A3N5U7D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
PQAKSTKDDLDAFARKVRAGANSAITQYFYNPDAYFHFVDEARALGVEVPIVPGIMPIVG
FTKLARFSDACGAEIPRWMRKKFEGFGDDVGSIRAFGLDVVSELCERLLKGGAPGLHFYC
MNQSALTMEICKRLG
>A0A423WQM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Valsa malicola|TrEMBL
MHIKEMIAEAEKTGEPSFSFEYFPPKTLTGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVSQAQAYFGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPRDKEK
WQAADDGFNYAKDLVAHIRTTYHDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDAGATF
IVTQMFYDVDNFLRWVGKVRARGIDIPILPGIMPIATYASFLRRANHMNCKVPQEWIDAL
EPVKNNDVAVREVGKTLVANMCRKIVAAGIPHLHFYTMNLAQATRMVLEELDWMPTDRSP
LKQALPWKQSLALGRRYEDVRPIFWRNRNKSYISRTMDWDEFPNGRWGDSRSPAFGELNA
YSIGLTGSNEENRKKWGEPKSVKDVATMFVKYLNKELDQLPWSEAPLTSEADSIREDLID
MNTRGLVTINSQPAVNGVKSSHPVHGWGPANGYVYQKAYLELLVSPDVFPELISRIDKNP
DLTYYAVTKAGNFRTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGMDW
ARCFDAGTPSRILLERMMGEWYLVNIVNNDFHQPRTIFEVMSGLQVKDLDVEVQADGPTA
N
>A0A074MWL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter litoralis|TrEMBL
MTPTLDQLHEHRTALDTPLFSGLPGDVDVSFEFFPPKTEKMEAQLWDAVQQLKVLAPEFV
SVTYGAGGSTRERTHATVSRIIKEAHLPAAAHLTCVGATKAEIREVAEQYWEAGVRHIVA
LRGDAGEPGAPFTPHPEGYAGAAELVKGLKEIADFDISVAAYPETHPDADCPQACIDHLK
RKLDAGASRAITQFFFSPETFFEYRDKLAASGIDKLVIPGILPVTNVATARKFAGACGAI
IPDWMDGLFEGLDEKPAARQLVAATVAAELCRRLYAGGVRNLHFYTLNRPDLAYAICHML
GKRPVGEKAAEAAVTGEAA
>A0A7Y2NX75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
SDPDKELARFAWKVDAGAEFAVTQPVFEPELLEAFLDGVGGPSIPLIAGIWPLTSLRSAE
FLENEVPGIHVPQSIIERMRRAQDRSIDAARAEGVAIAREVFQAVRGFVQGVHINAPFGR
VEPVQAVLREISGQASQ
>A0A1B1B6T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseochromogenes|TrEMBL
MALGTASTRTDRARTVRDILGAGKTTYSFEFYAPKTPKGERNLWNALRRVEAVSPDFVSV
TYGAGGTTRTTTVKETQQIVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPSGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDTDVAHFVA
KCRAGADYAITQMFFQPESYLRLRDRVEAAGCDTPVIPEILPVTSVKMLERLPKLSTAQF
PDDLKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQT
>A0A7W5GQ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvibacter caecicola|TrEMBL
MSSLSSLFPAFALPFSVEMFPPKGQFTLDAARTVAAGLAQARPSFVSVTCSAGGSGNSAQ
TVDIAALLQNEFAIPGIAHLTCVGATRASLDQQVRRMREAGITTVLALRGDMAEGQEPGD
FLYAKDIIPLLKQEGFTVGAAAYPEGHISCFSAADNLWHLKEKQEAGADFFVTQLCFDND
VLLRFCRQAKEAGVTAPLTCGIMPFLAKSQLQRMVFLCGSSLPAPIIKLLAKHEDSPEEL
RQAGIRYACQQLVGLAQAGVDGLHVYAMNQPDIALAAAEALAAEGLR
>A0A6I6IDN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus equinus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLIHPEKVSAIHKAYIEAGADVIQT
NTYAAKRHRLKGYGYEDKVKEINQAGVRIARQAAGKDIFVLGTVGALRGLKQCELSLDEI
IQETLEQVNYLLETNQIDGLLFETYYDEEEIIAVLKAVRPLTDLPIITNIALHEAGITEN
GKPLVEIFGKLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAIKGLKPVSRKFVTP
MVEEAELIKTVKQSETIVDKVKRQVTVIAEIDPPKTLDIEKFTEGVKALDDAGVSAITLA
DNSLAKTRICNVSIASLLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDILGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIKQLNKGKGYSGASIKKETTFTAAAAFNPNVKNLS
RCSRLIDKKIAAGADCFITQPIFNKEIIENLAELTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDDFLEKIEAVKDDKNKCQELALQESKALIDSALECFNGIYLITPFMRYDLTV
ELVNYIHQKVEEKKQKIS
>A0A7D4CDD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kroppenstedtia pulmonis|TrEMBL
MKKKDLKRVLSQRLLVGDGAMSTYLYQLGIPAGVPVEELTLSKPGWVREVHSRYYKAGAR
FIETNTFGANRERLSRYGLEGKVTRLNREAVFLARQAVGEDAFIMGAVGSIHAGRVFRYS
PAEYRDMFEEQVTAQLFAGVDGIILETFLDLEELVLALETIRPLTNQPIFCQIAMSEVGR
TQDGRTLSEAFQILKETGADGVGLNCRFGPLELQRALEKTIVPEGMILSAFPNAGRLGIT
EGEYQYKSTPAYFGERARILREQGLQIIGGCCGTTPEHIQAIASALKNLSPLPRVNPNLP
VEEVQARQSFSTIRITPTVVEKVKKSRTVIIEFDSPKDLDITDYLKGAEKLHQAGADAIT
LADNSMATTRMSNMALGSIIKEKIGVEPLVHITCRDRNLIGQQSHLMGLHALGMDQILVI
TGDPTRIGDLPGSSSVYDVNSFDLIRMVKQLNRGISFSGRPLKQKAQFVVGAAFNPNVSK
IETAVRRLEKKVEAGADFIMTQPIYDREAVQIVAEATRHIGVPVFIGVMPITSHRNALFL
HNELPGVKIPDSVMKKIEGKRGAEARQIGVELAKNLLDEAMLHFNGIYLITPFSYWEMTA
ELTQYIRQGELISLTGER
>A0A7X4K5L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium silvae|TrEMBL
MTAAPQPATGRTAETPLFAGARGDICVSFEFFPPKTEKMEEQLWDAITQLAPLDPSFVSV
TYGAGGSTRERTHATVSRIVRETSLVPAAHLTCVAASKAEIAEVVDQYWEAGVRHIVALR
GDPPPSDGGRFVAHPEGYASAAELVEGLMKRHDFEVSVAAYPEVHPEAASADLDLDNLKR
KIDAGATRAITQFFFSTDAYFRFLDKALAAGITAPILPGIMPVTSFTAIRRMSGNTEIPD
WLETMFEGLDERPGPRALVAAVAAADLCKRLYEGGVRDFHFYTLNRAEQAYAICQLLGLR
PKELAA
>A0A7Z1LQ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRTQLDRAAAKLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAQDALLDLKHFKAKVDAGADAAITQYFFNPDAYFHFVDE
VQRLGVQVPITPGIMPISNFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGAEVV
AKLCQRLVEGGAPGLHFYTLNLAKPTVSVLKLLQG
>A0A1Q5XRF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. P46E|TrEMBL
MKPDLRSAWKNNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYIEAGAVL
LESNTYSANYDKLSKFGLEAKVDEINRAGVRIARHAAGETGYVVGAVGSIRAGKRANLSS
TELKRFYAQQFSALLEEQPDGIMLETFYDVEELHLALRAVRKLSELPVICQLAVDETART
LDGLTLTEAFHILEQDGADIIGFNCRTGPNGIKRALKSLQGSLRLPASVYPNAGIADYVD
GQYRYGASPDYFGQMAPVFADMGARIIGGCCGTTPQHIAEISAALREYSPQPLPEPTAQN
NLERLTVQEHLGDNEERDGHEPTLVDLVKERHTVIVELDPPRDLDIAKFMRGAEALRRAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIKQLNDGIAFSGKPLKQNANFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIERIAKATAHLEIPIFIGIMPLASGR
NAEYLHNEVPGIQLSPEVRSRMQGLEGEEGRAEGVRIAKELLDAATRHFNGIYLMTPFMF
YDMSVQLLEYVWEKQGRKLSPLFR
>A0A645CYG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MAEIELQGTPDFFLGASVTPRFDPVDAQIFKMEKKIAAGAKFFQTQAVFDIETMRDFREK
TKHMDCKIMAGIIPLKSPGMAKFMNSNVPGIFVPDELIDRLKASAEGIEDKKEKNKAMVM
EGIKISGEFIKQLREEGLCDGVHIMAIGAEENVPLILDAAGL
>A0A645DE23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MRKRPGTIALSALIQYTFNIPVVAHLICGGMDADQLEDALVELNFLGIENILALRGDPPN
GEKRFVPMKGGYAHSSDLVKQIANLNEGRYLDSTLQDGRKTHFCTGVAGYPEKHAEAPNL
EEDIQMLKYKVECGAQYIVTQMFFDNTVFYRFVDDCRKAGITVPIIPGLKPIGSKRDLAT
IPQTFHVDFPSELVQLLNKAQKLSEIREIGVHWCTKQAKDLLAHGVPGVHFYTLGKAESV
SRIVREVF
>A0A417LFA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. TM09-4|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A431UE43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas maltophilia|TrEMBL
MPAPGSLRTEAFINTFSLEVSAKAMPALRAEADRIPRGTTISIPYLASEDDDARLAAART
VRALGFEPMPHLSARRIGSRVALERFLERAASEAGVEQCLVIAGDLATPAGPFADSISII
EAGLLERSGIKVVGVGGHPEGHPVMSSDDRWQALEGKCRAIETRGMAPVIITQFAFDADI
VLTWLAVLRARGVNVPVLVGVPGPASITRLMRYAAMCGVGASASMLARYGVSIGRLLGTA
GPEIFVDRLVQGLTDAHGLVSPHLFPFGGIAPSLDWMEQYRRRASGAGR
>A0A431UE43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAPGSLRTEAFINTFSLEVSAKAMPALRAEADRIPRGTTISIPYLASEDDDARLAAART
VRALGFEPMPHLSARRIGSRVALERFLERAASEAGVEQCLVIAGDLATPAGPFADSISII
EAGLLERSGIKVVGVGGHPEGHPVMSSDDRWQALEGKCRAIETRGMAPVIITQFAFDADI
VLTWLAVLRARGVNVPVLVGVPGPASITRLMRYAAMCGVGASASMLARYGVSIGRLLGTA
GPEIFVDRLVQGLTDAHGLVSPHLFPFGGIAPSLDWMEQYRRRASGAGR
>A0A1H9WNF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas subterranea|TrEMBL
MSRHEHPLGISFEFFPPGTDAGRDKLIQTRDELAARNPRFFSVTYGAGGSTQARTREIVR
KVSQSGVTTAPHLSCIGSEKALLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRDETGNHFDIAVAAYPESHPQAPSLDRDVENFARKMKAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIADF
GTDVVSRLCQRLLDGGAPGLHFYTLNQSKPVLKIVDNLSG
>A0A520SJ55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoricolaceae bacterium|TrEMBL
MSKQIKKAMQNWSIEVTPSSNKKINDFREVLPVGTTVNVTEIPGSDLERILSTVHQLASQ
EMNAVPHIAARGIESLAALEALITRYREAHVTEVLLIAGGYKQPVGDFSSSIDVLETGLL
ENLGIKKVGVAGHPEGSPDISKAGLGDALRRKNAIAQESGLDMYLETQFCFDAQAILDWE
AQIRKAGNRLPIRVGLAGPARLKTLIHFAVISGVGPSLQFLKKQARNVTKLLTVQDPYEL
IETLAPHIDPQSPSALESIHFYSFGDFSQTAYFANQLAAKGTR
>A0A1Z9J3J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. TMED169|TrEMBL
MKTALQRVLEAGKAAITAEVMPPRGADPVHTLAMATDLSGRVHAINVTDGSRAVMRMSSL
AVCRLLLDAGLEPVWQLACRDRNRIALQSDLLGAHALGIRNLLCLTGDPVKAGDQQTARP
VNEFESVKLLGQVDAFNRGEDPNGGSLADGATELFAGCAADPQSRSWSGLQRRLMRKREA
GARFVQTQMVMDPQALERFQKELAGPMEIPVLAGVFLLKSAKNARFINRVVPGACIPEEL
ISRLEGAPNPAEEGVAIASEQVRRYTGIVQGVHLMAIKAEERIPLILEMAGFSSLPG
>A0A099SG35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. HMP27|TrEMBL
MYIKDIFSRKKPIISFEIFPPKKESSIDTIYNTIDELAPLKPDYISVTYGAGGNSETRNK
TVEIASIIKNKYNIEALAHLTCMTSTRDEVNGILNDLKENNIKNVLALRGDLPQDTNFKF
PEPLHFKYAEDLIKDIKNHGDFCIAAACYPETHIESNSADEDFKNLKSKVNSGVDFMITQ
LFLNNKFFYDFKQRAEDKKINIPIEVGIMPVINSKQIVRIASLCGAHIPEKFTKIINKYI
DNPQALRDAGIAYATEQIIDLLSSGVDGIHIYTMNNPEVAKKIVSNIDSIVSALNSENRL
>A0A345QKN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. SK012|TrEMBL
MNTPAISFEVFPPRSVDAAFKLWDTAQALAPLTPRFFSVTYGAGGTTRDLSHDAAHVLRR
TSGLPVAAHLTCVGASKKETLETAERFAKIGITDIVALRGDPADGDTSFQPHPQGFANSV
DLIEALAETDKFTMRVGAYPDSHPDAVSQHANIQYLKRKFDAGADEAITQFFFEADTFLR
FRDACAAAGITKKIIPGILPVANWASARKFADRCGAVVPAWIEEAYRAAERDGRHDLLAT
ALCTELCSDLLDEGVEDLHFYTLNRPELTKTVCHAMGITPRSELSNVA
>A0A3L9M943|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium YIM 102668|TrEMBL
MKVTEHIERANGKPLFSVEILPPLKGQDVRSTFKTLDPLVELNPAFIDVTYHRQEFIYKQ
KDNGLLKRYQVRKRPGTVAICAAIQNHYKVDAIPHLICGGFTKEDTEDALIDLNFLGIDN
VLVLRGDPIKSEKSFVPEIGGHAHASDLIDQITALNDGKYLDDEIQESHQMDFCIGIAGY
PEKHFESPNLAMDMYYLKKKVELGADYIVTQMFFDNKKYFDFVNKCREMDINIPIIPGIK
PLTTFNHLTSIPQNFYIDLPEDLAVEVLKAKDKEVIKEIGIEWSINQCKELLEFGVPGLH
FYTMSNSVNTKKVAEAIF
>A0A2W6G6A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIEFI
RTEHGDAFHIEVGAYPETHPQATDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWIGRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLRG
>A0A1G6PGL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niabella drilacis (strain DSM 25811 / CCM 8410 / LMG 26954 / E90)|TrEMBL
MISGRSPAFCRLTRLAALQLPGARDKNGSHIKRETWNFNTGIFPLVLQPMKVIDHIKNAK
NTLISFEILPPLKGKGIEALYDHLDPLMEYKPAFINVTYHRSEHIFKKNPDGSFKKVIVR
KRPGTESICAAIMNKYNVDTVPHLICGGFSINETEDALINLNYLGIDNVLVLRGDAAKNE
TAFIPQPDGHPYAIDLLKQVVDLNNGVYLEEDLRNSRKTDFCIGVAAYPEKHFEAPNMET
DMAYLKAKVEAGADYIVTQMFFDNAKYYAFVNACRKAGITVPIIPGLKPVYTLKQLNVLP
KTFHIDLPTDLSKEMMKCRTNEDVEKVGTEWLLMQSKDLKKNGVPVLHYYTLGRPQIISA
VVKEL
>A0A246I2A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPVPGSLRAEAFINTFSLEVSAKAMPALRAEADRIPRGTIISIPWLASEDDDARLAAART
VRALGFEPMPHLSARRIGSRAVLGRFLERAASEAGVEQCLVIAGDLATPAGPFADSISII
EAGLLERCGIKVVAIGGHPEGHPVMSSDERWQALEGKCQAIEARGMAPLVVTQFAFDADT
VLAWLDGLRARGISVPVLVGVPGPASIPRLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPEAFVDRLVTGLTSAHGPVSPHFFPFGGVAPSLEWMARYRRRISSARSVIPEG
>A0A0U5IBS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAGTSAQAEAFINAFSLEVGAKAMPALRAEADRIPRGTVISIPWLASEDDDARLAAVRT
VRALGFEPMPHLSARRIGSRTALERFLERATSEAGVERCLLIAGDLATPAGPFADSASII
ETGRLERFGIKVVGIGGHPEGHPAMSGDARWQVLERKCEAIEARRMAPVIVTQFAFDADA
VLAWLDALRARGISVPVLVGVPGPASIARLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVKGLTSAHGQVSPHLFPFGGVASSLEWIEQHRQRVRGARGVIHED
>A0A139Q1U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MTLTDQGTAWPSWLSSHEIKKKRIMTMSRQTPSLSFEVFPPNPAVGNDKIISALQDMQEL
APHFISVTASNNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVG
VQKILALRGDIIPDVEPQKDFRYATDLIEFIKEQAPHFEIVGACYPEGHPDSPNQISDIQ
NLKKKVDAGCSSLVTQLFFDNERFYDFQDKCTLAGIDVPIHAGIMPILNRNQALRLLQTC
ENIHLPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYI
HQATHALFNHQSLG
>A0A5K7ZKU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina ovata subsp. sediminis|TrEMBL
MLRVFQNDISDPQQFVVTLELVPGRASTGRAVDTVMGIARDAFSDGRISAVSITDNPGGN
PSLSPDAIGYRIFSIGMDVIVHFTCRDMNRVGMESRALQLAMMGMKNILALTGDYAGKGF
GGQGAPVFDLDSVNLQIMLGMIGKRINAAGDPDAFFTGCAVSPFKKTEGECVAQYAKLSR
KVAAGAQFVITQLGYDARKFQELIEIGRHMDLGVPALGSVYVLTPKAAELMNQGRVPGAV
VTDPLLATVRQEWQDKTAGQAAAIERAARLGAILKGLGYRGVHLGGIHRDFSTVGKILDR
MQTIQDDWIQFLPEFNDPQPGGFYAFREAPPEPVTALVFGQQRQPVPIVDRVLYPLMRFS
HHLFFNFDSKLAPAYRLASHALDNSIAGRLFMHLGEHPIKLSLLGCQRCGDCAIQHVGFL
CPESGCPKHTRNGACGGSRGGMCEVYPDRRCVWFRAHTRLASNNKVSEMCHGCVPPRMWE
LNHTSSWLNFHLRRDHQSNGGEISGCCRQTTCHLLLGNTKERKDQP
>A0A520LMC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR92 clade bacterium|TrEMBL
MLDKISKQEKNIKEFMRGTSVEVTPGGARAIEDFSEILRPGTIVYVTFLPGSDFNATVET
VSRLKREGFYPIPHFAARSIESEKILEEGLERLKEEADTTEALLIGGGVDNPLGPFSASI
EVLRTGLFDKYGFKKIGVAGHPEGSPDITPQECAQAIQEKNDFSYHTDADLYLATQFLFE
AEPLFKWEKAIRSQGNKLPIHVGIPGLATIPTLIRHARQCGVGPSVRFLKKKPIDLFKMS
LSNTPLGKFINAPSSNPSKLIFDIVSGLTVDSDCLINKCHLYPLGGLKKSIDWLYQIQDG
NFSVANGDFIVH
>A0A8J3WBF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planobispora rosea|TrEMBL
MRELLAAGGRSFSFEFFPPKTDEGERQLWRAIRELEALRPTFVSVTYGAGGGTRDRTVEI
VERLAHETTLTPVAHFTAVNHSIRELRHLIGRFAGAGVRNILAVRGDPPGDPMGEWVAHP
EGVLYAEDLVRLIRQSGDFCVGVAAFPYKHPRSASVESDTEYFVRKCRAGADYAITQMFF
RAEDYLRLRDRVAAAGCDTPIIPGIMPVTQMSTIARSEQLSGAPFPPEVAARFEAVADDP
AAVRRLGVEHAAELCQTLLDEGAPGIHFITFNRSSATREVFQALDSAREAAPLTA
>Q8R926|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)|TrEMBL
MLKNEKLCNKLKEKKFVITVEISPPKGIDVTKTIEEARKLKGVADALNITDSPMANMRMS
PIALAHILQDHLNIETIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDNPSLGDTPQ
ARGVYDVDSVGLLKIIKALNSGFDYNGNKLDYPTSFCAGTTANPNDLRDEAIEKLHVKVE
AGAEFIQTQPVYDEEILFKFLDKVKDLKVPVLVGILPLKSYKMALRLMEKVPGIEIPEKV
IKRLQHGGKEEGINLSAEFIKNIKSEVAGIHIMPMGSVDFVFDIISKVEGIAISAKKAET
K
>A0A1I6DMJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoscipio geothermicus DSM 3669|TrEMBL
MKTESKLQKILDNGQFAVTAEIGPPKHSSAEGIRHHAEMMRDYVDATNITDNQTAIVRLS
SIAAGVHVQSCGIEPIVQMTCRDRNRIAMQSDLLGAYSLGMRNVLCLSGDHQKFGNHPTS
KNVYDIDSMQLIYYLRRMRDEKLFFSGEEIKEHEPRFFIGAVANPFADPFEFRVARLEKK
VEAGAQFIQTQCIFDMERFERFMEMVRERGIHERVHILAGVTPMKSWRAAKYIQNNVSGM
IVPDELVERLKNAEDPKREGVEICIEQIKYIKENIKGVHGVHVMAIAWEEVVPEIVERSG
LYPRPKVD
>A0A345P6V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquirhabdus parva|TrEMBL
MSTSTSTPISFEFFPPKTDVGAEKILKVHQELQALNPAYFSVTYGAGGSTRDRTLSTIDA
IHGQGAPVAPHLSCIGDDKARIAELLERYKAQGIRHLVALRGDLPSGQVGLGELPYARDL
VQFIRETTGDHFHIEVAAYPEMHPQAESFNKDIEQFIAKIKAGANSAITQFFFNADSYFY
FVDELAKRGVHTPIIPGIMPITNASNLIRFADSSGAEIPRWIRKQLAAFGDDSESIRAFG
HDVVVNLCQRLIKGGAPALHFYTMNHTEPTQQLVLDIR
>A0A1I4X2A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura madurae|TrEMBL
MRARLDRPPTVRELLATGRRSFSFEFFPPKTDKGARNLWRTIRELEPLHPTFVSVTYGAG
GGTRDKTVDIVERIATDTTLTPVAHFTAVDHSQAELRNLIGRFAAAGVRNILAVRGDPPG
DPMGEWVKHPDGVEYAADLVRMIRAYGDFCVGVAAFPYKHPRSPDIESDTRHFIEKCRAG
ADYAITQMFFRAEDYFRLRDRVDAAGCDVPILPGIMPVTQISTIERSEQLSGAPFPPEVK
ARFDAVADDPEAVRRLGIEHAAELCGELLGQDAPGIHFITFNKSTATREVYSLLDGAGYG
ASGRVPPMTA
>A0A7U7FPZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia enterocolitica (type O:3) str. YE12/03|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A512CL53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicyclobacillus acidoterrestris|TrEMBL
MATKDQVVWPAHSLQVGNRRYVIGDGAMATYLHQRGVPIRVSAEALNLSDPALVEEVHRA
YVQAGSTMIQTNTFAANRRSLARHGLGNRVREVNQTAVAIARKAAGQAASVYGTIAPVEG
GNRYGSALLNEERQQLQAFYEEQVEALAAAGIDGWILETFPDLEELLMAVEVVTTHSNLP
IVANLSPEEIGVTRDGVGLAEAFTALRAAGVHVTGINCRLGPYGILRSFEQLQPLADISG
QYAAMPNGGMLHQTDDGALSYTGDEENFADIMLRMANLGVTWLGGCCGTTPAHIRTLVSR
LKTSTDGSATTTAQHGHGAGRPWRVVNRDDKPAVGEILPPTPQSLVERVQQKTTIVVELD
PPKTLNCDKFLEGARALRDAGCDLITMADNSLGSVRVSNMALAGMLQQEGIEPLVHVTCR
DRNLIGQQSHLMGLSVMGVRHILLITGDPSRYGDLPGASSVYDVSSIDLTKMVRRLNDGV
GFSGKALTRPAKFVIGTAFNPHVRNFDKAIERLKRKVAAGADYVMTQPVYDAAMMERIAT
ATLHLGVPVFIGIMPLTSLRNAEFLHYQVPGMTIPEPVLQQMREASPESAQEVGLAIARD
LCDEACQYFNGLYLVTPFLKYDMTVSLTKYIRANTAAAVRSS
>A0A1I8AC55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steinernema glaseri|TrEMBL
MRKVEPLREIQDNGVDYRKKCLKKSPYVGVKPGAMVLDTTGAVECGLMKDAVKDVNGIAH
ANEYVPLHRRIEKQIESGTPFFSLEFFPPKTVNGVANFFTRLDRLREGGPLFVDITWHLG
SDPGTV
>A0A6G2IE75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HUCO-GS316|TrEMBL
MADRRFELICEVEPPTRPDLTQVRHQIGVLSPIADSFLIPDNHIGRATVSSVAVAHEVQA
MGARSIACLNSRDRNLLGFQRDLLTAAAYGVERFLFVHGDKPSAGGRTSELTVRAMIEQA
RAAEEDPAFGGCGPFRAGVTSGLRPLPGWKSAADFVFVQVSYSLESLLRWRDSVSLSMPV
YAGVMVLASAGMARNLAAKIPDIDIPEQLVADVERDRDAGVAAACEQVLAIRDSGAFDGV
HLVPVSRYRQVAALLERDVNAGRVSEKRGQAAPGTGRQAPFSLYGPRL
>A0A7G9G4Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium NSJ-38|TrEMBL
MKQLTAIMKERTAFSFELFPPKTDKGMENLPGTIEHLCEFKPDYISVTYGAGGTNVGKNM
DVCGMIQKAGTTPVTHFTCIGNTREGIKEQLQDYLDHGVNNMLALRGDLPFGWTGTGGDF
AYATDLVAFVRKEFGDKIEIAVAGSPEGHISCRSLEADIAVLKQKQDNGADYIMTQLCWD
MEQFKRWLDAIRKAGITMPVDVGIMPILDMAATINMALSRNACVMDRKLCEIISKNWIFP
NPFDKEPFDAAVDEKKAAFKEAGIEYTIKQMDEYRACGVDGIHMYALNKWKDVSEIINRS
GLRTIV
>A0A4U3AAM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGCSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7C4L5C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MKTFRQVLEGGEVLLFDGAMGTELYKRGIFINKCFEEANLTAPELVLSVHRDYREAGANV
LTTNSWGAGRFKLARHNLQDRLGEINRAACALARRVAGQDLYVAGSVGPLGPRLEPVGSL
TPVQALEAFREQILALAEGGADLILLETFGDVHEAVLAVQAAHEAAPGLPLITSLTIDMD
GNPLFGMELEEAVDLLVRAGTDALGLNCSVGPQPMLRAAQRIRRRHPAVPLLIEPNAGLP
RQIEGRMIYMSTPEYFATYAKYYLQEGVRMVGGCCGTTPAHIRAMAGAVRQYRAMCTDAP
FPDAECGSGRIEFIPLGRAPGGAAADASETAFETAAPGAPAAGSAGPSASSPARLPFASK
SRFAAKLAAGELVYALELVPPAGTTLDTIIQNAIRAREAGIDAINIPDGPRASSRISTLV
TAIMIQQKAGIETILHYTCRDRNLISMQADLLGAQAIGIRNILCITGDPPKLGDYPDATG
VFDIDSIGLTRMIYRLNSGYDISGRQIGTPTSLSHGVGVNPGLGGFESEMQRLRKKLEAG
AEWVITQPVFDPRVMEHFLDYLDKEGIRIPIIMGIWPLSSLRNALFMKHEVPGIEIPDSV
IARMERCRDVQEAREEGIAMARELFETFRGRIQGVQLSAPFGRVELALRVVGKA
>A0A7R9NE89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon GB37|TrEMBL
MWLPTEFYPPKEANKNEVEKRALVLKDVVEAVVVRDNPLAQVHTSPIATATLLLNVGLAP
IVQISIRDKNRLAIQSDILGAVTLGVKAFFCLEDCHQRVGDNPGAKGVFDLDCVQLISIM
KKIEHSLVGTRINPFAHPLELHLVNLSKKINAGVDFIQTMPVFDLERFKEFISLIKGENL
YLLAGVRPIKSWQALQSMSQMVIPENIVQRIKNTPENKQAEEGIKICVEIIKALKQIKGV
NGIHIFAHDWEEAVPILVRQANLK
>A0A6N8TK29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apibacter sp. B2912|TrEMBL
MKVTEHISNAKGKTLFSFEILPPKKGEDLQNIFSNIDPLMEFNPPFIDVTYHREEYEYRE
LPNGLIQKIVTRKRPGTVGICAAIQQKYKVDAVPHLICGGFNKEETENILIDFNFLGIDN
ILVLRGDPIKSEGIFKPHSQGHSYANELVSQVQNMNSGKYLHEEYAHGATDFCIGIAGYP
EKHFESPNLDTDLNYLKQKIDAGADYIVTQLFYDNTKYFEFVKKCRNVGITVPIIPGIKP
VSIKKHLTILPNIFHIDMPQELVMAVEKCKDNKAVYEVGIEWTVSQCKELMKQGVPVLHF
YSMGRSENIRKIAKQLF
>E0QTX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobiluncus mulieris ATCC 35239|TrEMBL
MASRVDWVAPDAGGVLDAPGTPVAFTSVSRGANPKSSRNPTRPVRVSFELYPPRNPDPFS
QAWAGIDRLLDAHPDYVSVTFGTSNSTSASSQSVLAHALQRLGRPVLAHLTCVGKTRTEL
STTITEMLDIGVRDFLALRGDNPKGSVNWEPAPGEFSRASQLVTLLREVAAEYLGDARAI
SIAVAAYPAGTVSARTNAVAALAEKQSAGADFAITQVFYNADDYGALLDSATYQGVSIPI
IPGIIPFTDAARLQRLEGLTGVSVPSRLQAISEISDPEERFLEGLSATLDFVNDLIQAGA
PGLHFYTFNRPRPVLDLVEHLRSRGFTHVDEDSSSELLDLMNAAMQRFSP
>A0A0D0X5G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus gattii EJB2|TrEMBL
MKITEKLQKAEKEGRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALKEAKSHGCQNILALRGDPVAGTST
WEPTPGGFMNAVDLVRYIHKHYPGDFCVAVAGFPQGHPETPGTPEGRAQEMEWLKAKVDA
GAEFIFTQMFYDTSIFFDWVKRVREAGINVPIVPGIMPIQNWEKFEKWVQRENIIVPSHF
YEALNPVRGDDEKVRQVGTKLVADMCKTILQNKEAGIKGLHIYTLNLEKGARMLLKELGF
EGRREQIAPLPWRPSLTPSRREETIRPIFWANRTRSYLSRTADWDEFPNGRWGDSRSPAY
GDLDGYPVSIGVTAPDAYNLWGHPTTSFDLHTLFARFCRGDLAKLPWSTQPPASETSLII
EQLAKMNELGYLTINSQPAVDGVRSDDKVHGWGPAGGYVYQKAYLEFFVSPDLLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWAHLYPAGSPSRKLITDTMNTSYLVNIVANDFRDGMSIFEPFLLNQTTVAKVVEGV
KGTVEGVVEGVKGVVSA
>A0A5P8PVJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Levilactobacillus zymae|TrEMBL
MDPAKPELSFEVFPPSSPAGTAKLTQTLAQLKGIAPSFVSVTCSNHQLNYEQSTISLAQA
VHRDLRCATMVHMPAAYVTKAQVRQILDQLEAAHIQQVLALRGDLDGAAPETDFTHASDL
VRFIKRVKPQFRVTGACYPEVHPDSPDRVADIRNLKAKVDAGCDQLITQLFYDNAQFYRF
REACAIAGITVPILAGIMPITNRQQALHVVQNCAASLPPKFKAILDKYRDNPVTLREAGL
AYAVDQIVDLVTHDVAGIHLYTLNQAATAQHIYDNTASLFAPVTVAD
>A0A1H4VQ25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TLI_105|TrEMBL
MIPTYSFEFFPPKTDKGEQTLWDAIRRVEALKPDFVSVTYGAGGSSRDRTIDVTKRIVTE
TTLRPVAHLTAVGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRGAWTPHPQGFTYAY
ELVELVRSLGEFRIGVAAFPEGHPRSDGSAADLAHFVAKCRAGADYAITQMFFDPEDYLR
LRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAKDDPAAAYRIG
VEHATRMGLRLLDEGAPGLHYITLNKSTAALEIHRTILSTRRVAAHV
>A0A4Y3KV53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas cellasea|TrEMBL
MHVPVSATLGGARPADRPLMSAPVTDAVPAPAPTRSRDVRAAVDRPTVSFELFPPRNPDA
APKLWATIQALGEARPDFVSVTYGASGKTRDTTRGLVRRLLRETSLNPIAHLTCVGTSRA
EVTAVVEEFLDEGVRSFLALRGDPPADQPDWRPHPEGLETASELVALLREIEERRCRGSL
AQKVRATVRPLSIAVAAFPRGNAGTGSTRAQDVAALLAKQEAGADFAITQVFFDAGSYLE
LVAEAREAGVTIPIIPGIIPTTDPARLLRVEALTGVTVPRPLLDRLGSVDDDAERHRVGI
RASVDLVNAVLDGGAPGVHVYTFNTHHAALDLLEGAHLGGGAPTAPDRAPGPQAGSPSPV
PAPTN
>A0A1F4CYN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_68_19|TrEMBL
MSYPASATEAGLQARVGELVAAGSLEISPRELHRAGEVAALLPAGTCVYIPSLPGLPLAR
TLEAVAAIRAAGLDPVPHVSARRILDREEFEKFIKQAVASHGVHRVLLIGGDEPRAKGPF
ADSLELLETGLLADSGIREIGVAGYPEGHPRIPGPVLSDSFEKKLRLARGQGLGLYVVTQ
FSFAPARMVEFCAGLARSAPAVSVYVGIAGPTDPVALARYAQRCGVSVSLRALRNLGSGI
ARLVTHTDPKDHVVALARYSVGREPSNVAGVHLYSFGGAVRTAAWMRERIAS
>A0A1A3NCU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium asiaticum|TrEMBL
MEAGCPKRMEFGPCGGVRPDGQCEMRPGACAFDDVVPWAGPAPARRPGRWQNSGPVVLTD
FSCAPFDRGDVAATAAILAPACDAVLVGEHQNKPDFPPTLMGSLLLDAGVAPWITLSCRD
RNRVVLEQELRGLRSIGVDTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGVTPA
VPETPTAPPVHARPARLVEKQRAGADVAVLNHVPYPAMIADFMAAARSAGLSIPVIAAVA
VFTDSVSAAVLQGLPGLELDHAVTEQVLTATDPVAAGIAAAVAEARELLSIEGVAGVNVS
GLASASGAHIGAEIKAEVGRRIRQEAQ
>A0A857EBA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia rhizosphaerae|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSSLKPQFVSVTY
GANSGERDRTHGIIKGIKDRTGLDAAPHLTCIDASREQLSAIASDYWNNGIRHIVALRGD
LPPGSGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPIAAA
>A0A7W5PRB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK275|TrEMBL
MTQKNDARRRDIAISFEFFPPKSEEMEGQLWNTVRDLQDWNPEFVSVTYGAGGTTKAPTL
STVTRFLADTPLATASHLTCVSATKEETHQVVDSFRKAGVTHFVALRGDAPGGVGAPYQP
HPGGYANAAELVAGLKQIGDFEISVSAYPEKHPESRDQAADIDMLRQKAENGADRALTQF
FFDNDNFERYLDKVRAAGVKIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGYDD
KPEERAKVAAEVAAEQIEDLIRRGLHEFHLYTMNRAPLVSAVLDNLGFSRQTVRSAGAAA
>A0A6G7YZM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sanguibacter sp. HDW7|TrEMBL
MSITGTGGAPARPTVSFELMPPRNPDAAPKFWATARALLAARPDFVSVTYGAAGTDRATT
RQVVQTIARDTPVLPIAHLTCVAATRDHVTEVVREFLDAGVRSFLALRGDPPAGQPDWTP
RPGGVNSSEDLIRLLQQVEAVRCGESPASALRGATRPLTIAVATFPGGNLAAGTTPAQEV
ERLLVKQEAGATFAITQLFYEASTYVDFVERARTAGVTIPILAGVLPTTEPRRLHRVAEL
TGVPVPVRLTSELEALPEDERHAHGMRASIALARDVLDAGAPGLHVYTFNNAAPALDLLE
GVHLGGGAQIASDLAGGPRVGEPLRDVARVDGP
>A0A522YU85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosotenuis sp|TrEMBL
MAAAQNAIYEARGAAYVAGSMGPLGTGIQPLGTVSAEDAAAVFREQAGALIDGGVDLIIL
ETFVNFKELEIAVAAVRARKADIPLVAHMTFGEDGHTPLGEPIEKVAAAMDAMPIDVLGV
NCSVGPAPMLEMVTKMATVTNKPVSAMPNAGYPRMHEGRLIYMTTPEYLETYAKRFIRSG
VKVIGGCCGTTPAHIRALHHAVKALAPARPAVEVKESKKEEAAPIVPTAEKSPLAKKLSQ
GKFVTCVEILPPKGADPSKVLDMAKQLKDAGVDACNIPDGPRASARMSPMSLALLFEQKV
GIEPVLHYTCRDRNILGIQSDILGAHAIGLRDILAVTGDPPKLGNYPEATAVYDVDAIGL
VKIISNLNRGLDVAGNRIGSPTAIHIGVGVNPVAINLEQEIARLRQKVEAGAEFIFTQPV
FDTNLFIRFKNLTKDITIPTLIGILPLASSRMAEFLHNEVPGMSVPDGIRKQMADAGDKG
AELGVELAIEALEAMRGMVQGVYVMSPAGGVKAPLAVLKKYL
>A0A6N4HIX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus sp|TrEMBL
MSLTALFKNKTVFSLEVFPPKKDSPKEAILPTLQQLQSINPDFISVTLGAGGSDHYTGTV
QIADLIQNQLNIPAVAHVPGLYQTREQVLNLLDNLSEINVKNILALRGDKIPGKQPVGDF
NHANDLVAFVHQNRPDFSIASACYPNCHAEATGFVDDIAHLRTKVDAGADHLISQLFFDN
QAFYDFQEKAEIAGIHVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSREA
MRDAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHR
S
>A0A8F9UD47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya zeae|TrEMBL
MSFFHANHQEALNQNLAELQGRINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPLGGGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPIASA
>A0A399JBA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Galactobacter valiniphilus|TrEMBL
MPHYPAPPPSLSYELFPPASAAAAERLEVSLEALAHTEPDYVSVTYSGTPHRRRATLDLV
DHLVRDTRLRPLAHLTCVGESAESLAGLVRHFIGLGVRGVLAMRGDLPEDPAADVGEYPF
ARYLVELIREVEGQYSAALGAGRLSVGVAAYPVRHPESPSFQHDVEVLVGKQRSGADYAI
TQVYFRPEDYTQLVDAARRAGVTIPIIPGVLPVDSPDRLARLAKLTGVEPDPLLGHALET
ASDEAERRRIGVEFAASLVRRALGDGAPGVHVYTFNRHEGAIDLVERLDLPGQRTDARHG
LAARVGA
>A0A546X2I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium salinitolerans|TrEMBL
MVIKRITHKLPDISAAPIIPASIEASPAQVLGATDLAGLFPQGVRVYLTDTGAASQERLV
EAAAHLRDLGYEPVPHLAARRIPSSAAFVEQVRRLAGEAGVTDVLVVGGGVERPVGPFAS
SMDMLSTGIFDRCGINQIAIAGHPEGSPDFNDDTAMAALRLKRDFAERSDAAMRIVTQFG
FDPARFIAWAEGLIASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LARGHSPESIVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGAADRSAS
PDSRAG
>A0A0E3YGL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea oxalativorans|TrEMBL
MTQPSFSFEFFPPKTADGAEKLRATRAQLFPLGPKFVSVTFGAGGSTQQGTLDTVIEIQR
EGVDAAPHLSCVGSTRENIRDILTTYRDHGIRHIVALRGDLPSGMGEIGEFRYACELVEF
IRAETGDWFHIEVAAYPEYHPQAKSPRHDLEHFANKVKAGANAAITQYFFNADAYFRFVD
DVARLGVDVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDREAIRSFGLDV
VSALCERLLKEGAPGLHFYTLNAAAATKAMWQRLGL
>A0A1I3VIP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium albiziae|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTGRTIKRILTETGIPAAAHLTCVGATREEVDAVIREFQNIGIERFVALRGDPASGVGN
TYRPHPGGYQNGADLVAGLKAIADFDISVAAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYVPIVPGIQPVHSFRQVANFSRKAGAHVPAWLAERFE
GLENDPQTHALVASAVAAEQVMDLVERGVSDFHFYTMNRSDLVFAICHMIGIRAEGAATA
QAAPAAA
>A0A2T9Q551|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Cerro|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A817AEQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria magnacalcarata|TrEMBL
MILTHNENRTLSSHFNTYQNDAGAEKISSSRFNNFKRSDSETRLLTAKGCCLESIKYMSL
AEKIHQRIANNDRWYSLEFFPPRTASGAANLIGCFERMAVGQPLFCDITWHPAGDPAGTK
ETSSMMIANTMLNYCSIDTMLHITCYGAKKETMLEYLWRAKEFGIRNLLALRGDPPVGEE
WIPEKSDFRYASDLVKFIREHFDDYFVICVAGYPQGHPDMVSYEKDLRYLKEKVDCGADF
IITQLFFQPETFIKFESDCRSIGIQCPIIPGIFPIQAYASLKNIVRLAKLDVPEEILACI
EPIKDNDEAIRNFGVQICVDLCRILLDSGKVHGLHFYTLNREYATIEILRKLDLWLEDPP
LRALPWKKISKNYVRSKENVRPIFWSARPKSYVHRTLNWNEFPNGRWGLSSAPSFGVLTD
YHLFYMKIDATRDALLDEWGHELADEQDVWRMFACYIAGEKNGTDKIVHHFPWKDEDISP
ETNFIHDHLIKYNRKGILTINSQPAVNGKSSTDSIFGWGVKNGYVYQKAYLEFFTSEKNI
PALRAVLKKFPGVNYHFVNKSGEVNETNTDGEQPIALTWGVFAGREIIQPTVVDPISFMI
WKDEAFNLWMECWGKLYEQGSRSYSIIEEISNTYLLVNLVDNDYPQDSCLWALLDAMFEY
QKANSKDNNC
>A0A7V9QMW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
MSDRKELLDRLLDPLQVVVFDGAMGTQLYAKGVFINQCYDELNLRAPDLIREVHRAYIKA
GAEVIETNTFGASRAKLAQYGLEADVTKINLEAAKLAREVAEDDVLVAGAVGPLGIRLEP
YGPTSLLEARQMFAEQMNGLKEGGADLFILETFADVHEIEQAILAAREIAPDFPIIAQMT
IGSDCLTPYGLSPEDIAKTLDALGADIVGLNCSVGPQTILDAIEKMTPVTRRKLSAQPNA
GMPREVSGRSMYMASPEYMATYAHHLVQAGVKLVGGCCGTTPEHIAAIVEGIRPLVPRQR
KPVRDRRVHQAEIPEEPKGVAPVPFADRSKFSAKIARGDFVTSVEIVPPRGVDATRMLKD
TAALKAAGVDAVNVPDGPRAQSRMGALLTSLLIEQRVGIETVTHYCCRDRNLLGMLSDLL
GAAATGLHNILLITGDPPKMGPYPNATAVFDIDAIGLTNLVSNLNRGLDPGGNPIGAPTQ
FAIGVGVNPAAIDPANELSRFEWKVDAGAEYAITQPVFDAEQLERFLGTIDHTRIPIIAG
IWPLVSLRNAEFLANEVPGVTVPQPIIERMRRASAKSKEAGVAEGIAIAKEMLERVRPLV
QGVQVSAPFGKVELALEVFGDHIKSEATTQ
>A0A842WDP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon|TrEMBL
MSGLSESLGKGFTVTTEVKPPRGPDTTGFEGEIGMLKSLKGLTAVNLVDSPSARLFMSSL
GASIMLKQAGLEPIFQMVCRDRNILALESDLISASAFGIENILALTGDHPSRGASDHPDA
KPVYDLDSTSLIRTISLMNEGRDITGKELKGSTEFYVGGAISPGVNPVEPEVLKVKRKME
AGARFFQTQVVFDLGVVEDFMEKADEMVGDIRGRVLVGIIPLASERMIDFLNRLPGILVP
EDVASRVVKADDPVAEGVSVALELIDGVRSAGMAGAHIMPVGRLNSLERILADI
>A0A0P4WD38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scylla olivacea|TrEMBL
MVKEEVADQLLAMASSHLSPKDSSIALPILKEILIQRENAKSSDHISPEDESHLIHEPEY
LSGYHNLKEKIQSRIESKDKFFSLEFFPPRTKGGAVNLLARFDRMREGDPLFCDVTWHPA
GNPGGDTETSSLTIAGAALNYCGLETMLHMTCCSMTKSEISHHLQRAKEVGIRNILALRG
DPPIGHDDWVAPGNGFSYAADLIRHIRKEFGQYFVLCVAGYPNGHPEAVSYEDDLHHLKE
KVDAGADFIITQLFFKAQTFIKFVTDCRAIGIECPILPGIMPIQSYDSLRHIVKLSKLDV
PQDIIDAVTPLKGNDEAIRNYGIHQTTTLIKELFDADMAPGIHFYTLNREVATTAILKQL
GLWAATPRRPLPWKMAANHKRSGEDVRPIFWASRPKAYVFRTQHWDEFPNGRWGSSESPA
FGELKDYYLFYLKSKSTKEELLNMWGERLESEQDVWDVFHAYLTGSCNPKTGKKVTKVPW
NDDELSAETALLTEKLANFNKRGVLTINSQPNVNGASSEDPVVGWGMPGGYVYQKAYLEF
FTSKDNVDALLNVMPLFPRINYHIINRAGTEDFSNCHKHRSTAVTWGAFPGTEIIQPTVV
DPVSFRAWKDEAFGLWEEQWGKLYAENSKSREIIQHITTNYYLVNLVDNDYPKEPCLWDV
LESMFTWRTLRQENVLGLSDSLPQC
>A0A7Y3TID4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. CLA17|TrEMBL
MKVTEHIENAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
IMALRGDAMKDEQYFIPKAGGNDYAIDLVKQISLLNQGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNTKYFEFVAKAREMGITVPIIPGIK
PIAVKRHLQILPQIFRIDLPEDLIHEVDKCKDNAAIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASRIF
>A0A694XK36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEIEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A098AWY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfitobacterium hafniense|TrEMBL
MENRFKQSLLDPNTLSVTWELVPGRGAREKAQESALLAAEQAAKGGKVHALTITDNPGGN
PAILADYLGQEILKLGIEPLVHFTCKDKNRNQMESQLYALDRAEVRSLLVMTGDYTVSGF
KGRPKPVFDLDPTHTLELIAQMNEGLGIPGPKGMSYHQPSDFFAGAAVSPFKGTEAEQMV
QYYKLKKKVTSGAQFIVTQLGYDARKIHEVLQFMKLNDLNVPLVGNIYILPFGAAKIMNQ
NQLPGCVVTDKLLAEIDKERTAEDKGVSARLLRAAKMYALMKGMGFAGVHIGGHNIKYEQ
VEYVIEKGEELSKDWLALVPEFDYPMPNGFYYYEKDPKTGLNTTTPVNRKNLPLDAPVGV
AYSGMRLMHSMLFTPGKNFFPVMRKIYKGRKDNRKHGLEHLAKVITNDCKDCGDCAMFEL
AYLCPMSQCPKNQRNGACGGSYQGWCEVYPNQKQCIYVRAYARLKKYDEEGDLDSHHIPP
ANWDLYQTSSWSNFFLGRDHSGKILGIPTPEEEAKAKGADPAK
>A0A5T0S8H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELRA
>V4JB11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp. PB-SRB1|TrEMBL
MFNYPYIVELLSPKRSPETDTKNLLARFAERFEKVMEAGWGVSIPDNPMGQPRLGALETI
ELTGLSLDPEKTVMNLNTFHEKDELDALLKKADAARLQYILVVRGDGGPLLPTLDPESIG
GRFSVATSIDLLRYINTAYPSRFITGAAFNPYKPADFELDRARQKIDAGARYFITQPIPG
PDKNVDMLKELETTVVVEAWMSQNVELLYKSVGKKDSTEEKGFNPAESLRSLHSHYPDCC
VYLSMLSFKQQWKALLPRM
>A0A5T1D0D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSVNSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A3H9R458|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A497GRN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoprotei archaeon|TrEMBL
MKRIYSRLMEELLSGKFVFTAEIEAGKTTSLDKVIEAAKMLKNYVTAINITDNPGACAHM
NPLVPAYVIQRDVGVEAVYQITCRDRNRIAIISDLLAAAALGIRNVLALTGDHVTMGDNP
EAKPVFDLDSASLVYLIRRMVDEGVDLAGNKIEGEVKFHVGIAANPNAMPLELEILKIER
KVRLGIDFIQTQCVFDMELTKEFLREVKKFNVPVLVGICPIRSIGMMKWYIKECPGGIKI
PMEIQERLLTARERRGKKGVLEESIEISAELIKEIRKTTSAAGVHIMAIGFEWVIPQIIE
RTGLKC
>A0A0C4UTD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria montana|TrEMBL
AYGIHLGTEMCKKILAHGIKTVHLYTLNLEKSALAILANLGLIDMTKIKRPLPWRPPANV
>A0A259NPN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. 39-45-136|TrEMBL
MELSVEFFPPKTPEGESKLHVVRERFSETLKPAFYSVTFGAG
>A0A2C2BRN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDVAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A437SCN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0A6VGI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A2S0WJH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium chenweiae|TrEMBL
MRNKSTARELRRLLESSRYEVLPTASIEDKILESLPRGHTLTVTASPGKGMDATLDLAER
LVGHGYQAVPHLAARMISGRAELTEIVDRLRAIGIDSVFVPAGDADPAGDYAGSLDLLQD
LTAMGSPFHHVGVTGYPESHPTIADDVTVQAMWDKRHHATTLVSNLCFDPQVVRTWVQRV
RSRGAVMPLLIGMPGPVERTKLLAMATKIGVSESTRFLAKNKSVFARIAMPGGFSPEKFL
ERIAPTTQEPASHVEGLHLFTFNQVAETEAWRQELLARLGATAHSA
>A0A7S3G8W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Palpitomonas bilix|TrEMBL
MKYFLSKQYSNAKKLHTIIEVFKPATREGENSLMERLNRLATLNPALFSISSQNHQHENN
TLSLTQLVREDVCAEVQVHLQCDEPLEILRANIASAKAFNVRHFLFFVLRQPQALVQEGG
EVSHDSVAIEEALKKMRQLLHLLGEEQSIGVMVPYCDTRDEQIWASVARLACPGIDYVVL
PMIATTQSYSAS
>A0A7V7RIB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter sakazakii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPAGSGKPEMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPALELKT
A
>A0A2R3MVN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides heparinolyticus|TrEMBL
MRVIDLINSHEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLYQRNRLRRRPGTVAVAAAIQNRYNITMVPHILCSGFTREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFTPEGNGYHHAIELQEQINNFNKGIFVDGSEMKITKTPFSYGVACYP
EKHEEAPNIHTDIYWLKKKMETGAEYAVTQLFYDNRKFFDFVERARLEGITIPIIPGIKP
LKKLSQINMIPKTFKVDLPEELTKEVLKCKSDKEVQQVGIEWCVQQCKELIAKGVPSLHF
YSVGATDSIKEVARQIY
>A0A085U3L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia ruckeri|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTREMEDTLWSSIDRLSTLKPKFLSVTY
GANSGERDRTHSIIKDIKERTGLDAAPHLTCIDASPGELREIAQDYWRSGIRHIVALRGD
LPEGSGKPEMYATDLVALLKNVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATLTNVRVPHWMTSVFD
GLDNDPETRKMLGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRP
>A0A8C8FMC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
MPASIASMVNNVQRVDDTWRTCTKSNSSGTSNSGGESSKESSRSSTPVLAADRTERLRDK
MRRRTESGDHWFSLEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETS
SMMIASTAVNYCGLESILHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEE
EGGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEADSYDEDLRHLKEKVDAGADFIITQ
LFFRADTFLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIK
DNDAAIRNYGIEQTVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLP
WAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYL
KSKSSKDALLKMWGEELTSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMM
DELDKVNRRGVLTINSQPTINGKPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKV
LKKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAF
ALWIEQWAELYDDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPE
EQPTEQPVEQPAEESPVEDQSPK
>A0A1A7PQL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallibacterium genomosp. 3|TrEMBL
MSYAKEIDVLNRSIADLNGEINVSFEFFPPKNEKMENLLWDSIQRLKVLQPKFVSVTYGA
NSGERERTHGVVKAIKQQTGIEAAPHLTGIDASPEQLKQIAKEYWDSGIRRIVALRGDEP
PGYSKKPFYARDLVTLLKGVADFDISVAAYPEVHPEAKSAQADLIFLKQKVEAGANRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFVQLQKMAKVTNVRIPSWMYKLYDGL
EQDQTTRNLIGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGLRPHLAAA
>A0A2V5YNT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRGQCPTFSFEFFPPKTPEAAETLYRTIRDLESYAPDFVSVTYGAGGSTRELTH
DLVERIQNTTKLDPIPHLTCICHKEEEIEAILLRYARSAIGNILALGGDRPPEMAYDKSR
DSFQHAIDLIKFVRRFNESGVHPDRRGFGIGVAGFPEGHPATPNRLIEMEHFKAKVDAGA
DYVITQLFFENSDFIDFRERCALAGIHIPIIAGIMPITSMSGLKRMAELAGGARFPAKLL
RALQPWQDDAAMVRRVGIQYALEQCRDLLENDVAGIHFYTLNRSDATRIIFDSLGISRHR
NAHASSL
>A0A6G1LY96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orbilia oligospora|TrEMBL
MHIKDKIAACEKAGKPCFSFEYYVPKTAQGVQNLYDRMERMGSFGPQFIDITWNAGGRLS
NLTTEMVNVAQTVYGLETCMHLTCTGMEKEKVDNALQEAYNGGCTNILALRGDPPRENEK
WSAVPGGFRYAKDLVKHIREKYGDYFDIGVAGYPEGCDDEVDPDILLDHLKEKIDAGGTF
IITQMFYDVDIFLDWVNKVRAKGITVPIIPGIMPIHTYAAFIRRATWTKIHVPEKWLEVL
EPVKNDDVAVRDIGRDLVVELCKKILAAGINQLHFYTMNLATATRMVLEGLDLMPSLEAR
ELPALPFKSSLGLGRREENVRPIFWKNRHKSYVARTQEWDEFPNGRWGDSRSPAFGELDT
YGIALKGTTEQNIKLWGRPETVAEIADLFVRYIDGKLETIPWSDSPIDASAEPIKAQLSE
LNKRGFLTTNSQCALNAVKSSHPIHGWGPKNGYVYQKMYVELLVSPDVLSELITRIERSP
DLTYYAVNKAGVLHHNAPAGGSPNAVTWGVFPGKEIVQPTIVELISFLAWKDELYRLGED
WAACYPQSSASRHIISSVMENWFLVNIVNNNFLDNDSIFELFKDLKIDNLNEKIPVDEYL
QNLKMTDGTNGTAHEATNGAPAA
>A0A1K0HFT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ustilago bromivora|TrEMBL
MASSNEAATSATATPSDPAHITTKIQSALSRDAPFWSFEFFPPKTTQGLANLYNRIARMR
ANLDPSWIHVTWGAGGTTGGKSLELAGRIQKGKLHPDLQLVQTEAKHLDPGPQQQHLDNV
KGGQPCEQGDLDACDVCLHLTCTNVEKSSLDETLATAKRLGIKNILALRGDPPRGDEYWV
AADERFQHATDLVRYIRDNHGHFFCIGVAGYPEGHADYVDRDVKRDLGYLKQKQDAGAQY
IVTQLFYDVDRFLAWYKECRAIGITIPILPSIMPIQNHQGFRRMTNLCKVQIPQPILDAL
EQIKSDDAAVKEYGVSLSIHMIGRIFLESDIRGFHLCSLNLEKSIERILDGLGWKTDLGA
QVEAEAPLTAIPAHIHLEKTQNQMLCDGTGAQTPKDLKVTTQEALARTLARTSASYQVPE
TTTWDEFPNGRYGDSRSPAFGEMDGYGVSLKVPPQDALRIWGHPLTLADISKIFASYLEE
RIACIPWCDAPLMSETLQIRHHLLSLNRLSEPSTTDAAQSGKGWWSVGSQPAVDGAPSTD
PTVGFGPPGGFIFQKAFVELFMSAADKDRLISRIDSLGPNAQITYFAGNAKGDFASNLGD
GEANTVTWAVFPGKEIVQSTIIERESFEAWRDEAFEIWSEWSLLFPKASASCKLIEAVKE
ARWLVTVVHHDYKDIEALWRFLAE
>A0A0S2FM23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter capsici|TrEMBL
MLPISFEFYPPKTDEQRGQLDKTAIKLKPYAPSYVSCTFGAGGSTLNYTPETIRRLRAKH
KLDAAPHLSCVGGTRAEIRELLQLYREIGCKRLVTLRGDLPSGMASAGDLRYANELVEFI
RAETGDHFHIEVAAYPETHPQARDAHSDLENFKRKVRAGADGAITQYFYNADAYFRFVDD
VRAAGIDIPIVPGIMPISNFSQLRRFSDLCGAEIPRWVAQRMQAYGDDVDSIREFGADVV
ARLCSRLIEGGAPGLHFYTLNLSKPTLTVLSRIA
>A0A8D0MEV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGGDQWEAEEGGFSYAADLVKHIRS
EFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACS
EMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVS
LCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRP
IFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQE
LTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINS
QPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDGE
NITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSR
MLIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>A0A2V6IP54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMLRESPTFSFEFFPPRTPEAAEILYHTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIEAILIRYTKSAIGNILALGGDRPRGIDYDKAR
DSFQHAIDLVKFIRKFNESGAHPDRRGFGIGVAGFPEGHPATPNRLLEMDHLKAKVGAGA
DYIVTQLFFDNRDFYDFRERCALADIHVPIIAGIMPIISVSGLKRIAELAGGARFPARLL
RALQRCENDPEMVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRIIFDSLGIQRRR
SAQPQTV
>A0A1S1M605|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides chelonae|TrEMBL
MTTNPLDHDASVAELQDPGSIADRLAGVQPGDVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDLE
RDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEEQLLRAAGDGPEEDRDEVRKVGVEVATSMAARLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A8D0UWB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MDRPKAKGLPAGQCCPSLGVRALEAGISRSSVPPAISRSSAMVNEPRGNGGPGPRCEGSS
SGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEVTG
YLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACSEMGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKVGASLGHRVRGRHIYA
TIRQSRSAPPIQALCQTDTQTEPGPCPLRAPSLAREAIRG
>A0A0B3SN00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mameliella alba|TrEMBL
MQRPEISFEFFPPKNIEATFRLWDAVQVLSPLAPRFVSVTYGAGGTTRDLTRDVVATLHK
HSGLRTAAHLTCVNATRAETLAIAEGFAEAGVTDIVALRGDPPKGAAGFTQHPEGFANSI
ELIEALAETGKFTQRVGAYPDCHPEAADMDANIAWLKRKLDAGADEALTQFFFEADTFFR
FRDACQKAGIDGDKLVPGILPIENWNGARRFAESCGTYIPQWVSDAFEKAQRDGREDLLA
TAICTELCSDLLEGGVDKLHFYTLNRPELTRDVCFALGVTPEVALEQVA
>A0A1S3C5N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cucumis melo|TrEMBL
MKVIDKIRAATTGDGGRVVFSFEYFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGS
TADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKANGLQNVLALRGDPPHGQ
DKFVQIEGGFACALDLVKHIREKYGDYFGITVAGYPEAHPDVIGSNGVATTEGYQSDLAY
LKKKFDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCK
TKIPDEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHIYTLNMEKSALAILM
NLGLIEESKVSRSLPWRRPTNVFRVREDVRPIFWANRPRSYISRTIGWDQYPHGRWSDSR
NPSYGALTDYQV
>A0A132EAK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomultivorans|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATKTICERLDP
>D1JD40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon|TrEMBL
MGDEVYSDLMRELREGEYVFTGELEPEKAGDVNEPIEMARELVGMVVACNVTDNPQSFAY
VNSMAASYLIQKETGMECVYQLRCSDRNRMALLSDVLGAGALGLKNILALAGDHVSLGDT
PDAKPVFDLDSTTLIKLIRTMVDEGKDLGGNEIHNPPKLHVGGAAAPGAAHLKAEVGKVK
RKINAGVEYLQTQVVYYTDVLDKFFDELGKVDVPILVGIFPARTFGQADFFDKYVAGVDV
PPDYLEAMRATKAIKDKEKKKEEVDRVNIEFFTGFLEHLKGTPAAGCHMMAVGYPRIIPP
LKKLME
>A0A0P9Y958|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. maculicola|TrEMBL
MEVSSPMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLN
TVLQLENEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGEL
RHANDLVAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFN
ADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQ
SIQAFGEDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A5P0WXK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHSHATDLLKQVNQFNEGFFFDGTPIKHSGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQMGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDDDAKQLGIEWTTAQVQDLFEHGYNNVH
FFTVSAVDSVKQIAKILF
>A0A183ITV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Soboliphyme baturini|TrEMBL
MTDLSGYGKYISPYMGETDWPVQCNGNDYVPLAERLRERIKSGVPFFSLEFFCPQTRAGL
KNFPIEFRSLRIDCFSKADPLFVDITWSYKNNIDIYKETSTISLSEAVLNFCFTDVVLHL
TSAPYTKAQMLLYLRLIRNPPLWSLWTLLEP
>A0A126Y8X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albidoflavus|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDRVTAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A1E7TZ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax boronicumulans|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPQFCSVTYGAGGSTHQGTFGAVQEILAE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFATKMKAGADSAITQYFFSPEAYFRFVDD
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLQEGGAPAIHFYTMNQSAATLAILERLD
>A0A4Q9P4B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dichomitus squalens|TrEMBL
MKISHKIEQAAKEDRIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRSS
ELTSELVKTCQKLIGIETCMHLTCTGMPKEKVDTALREAKQHGCRNVLALRGDPPVGKEW
EAVEGGFSYGVDLVRYIRAEYDDYFDVAVAGYPQTQTLPPAEAAREMQYLKDKVDAGANF
IFTQMFYDIDMFVAWVKAARAAGITVPIVPGIMPIQTWNGFQKATQLAKITVPQFFLDEL
EPHKNNDEKVRELGTKLVAKMCRQILAADIGIKGLHFYTMNLEKGCRLLLEELNLVPRVE
VVKPLPWRQSLTPNRRTENIRPIFWANRTRSYLSRTENWDEYPNGRFGDSRSPAYGELDG
YGIWIKQSKEDALKLWDTPTTVEQIRALFTKFCLGQLSALPWSDTAPSSETTIIAQQLAK
LNELGFLTINSQPAVDGARSDDRVHGWGPANGYVYQKAYLEFFVPPELLELLIPHIERDI
NITYYVINARGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGRQW
AQFYEPDSSSRQLIDEMMSTYYLVNVVHNDYKKPDAIFEPFFKAGAEYAAKHTATNGTAN
GTAN
>A0A3D4A1J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MPGLADLYKSDSAVLSFEVFPPKTEKGEAVLFQHMEKLVDHKPAYMTCTYGAGGTTQSKT
LEITSRIKQQFNIPVASHLTCVGATIDQLRQYLTDAERQQIDYIVALRGDPPQGSETFEA
VEGGFHHANELVSLINHEFPHYGVAVAGYPEKHREAPSMEVDLQNLKHKVECGADIVITQ
LFYKNENFFQFREACQRAGIDVPIIPGLLPVTNLAQIQRITSLCGAELPESFVQRLSEKD
DPEWQFKVGVEQCSEQLDELLQAGIPGVHFYVLNKSQATSAVLDAVPLA
>A0A560CWP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum brasilense|TrEMBL
MTSGIPSVSFEFFPPKTEKMEQSLWQAIQRLAPLAPSFVSVTYGAGGSTRERTHNTVTRI
QKETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPETEGGVGGRYVPHPG
GYAYAADLVAGMKKVADFEISVAAYPECHPEAPSAQFDLDNLKRKVDAGATRAITQFFFD
NDAYFRFLDRCAAAGITVPIVPGILPITNFARAVEFAGKCGAAMPQRFAETFEGLDADPE
TRQLVAATMAAEQCQALQAQGIKEFHFYTLNRSDLTVAICRMLGVKAKQPAVS
>A0A1I7D676|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas marincola|TrEMBL
MSKERRYSFEFFPTKTEAGHEKLLATARELATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVETAPHLSCVGDSKAELRELLALYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VSFIREETGDQFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVDRVRKMGIDLPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIESIQAYG
EQVITEMCERLLQGGAPGLHFYTLNQSAPSLAIWNNLKLPR
>A0A0Q0B879|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. syringae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A6L8TXR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSVIDKIRTAKSPLFTFELLPPLKGHSIERVYSTIDRLMEFSPAYINFTSHRNETVYRER
PDGLLEKKVVRKRPGTFALAAAVKYKYNITVVPHVLCGGFTKEETENVLIEMNFLGIDDV
LALRGDPPRGSRSFIPEKDGHSYTSELVGQIVDMNNGKYLEDSLQDTAPTSFCIGVAGYP
EKHFEAPNRQVDLENLKIKVDAGASYIVTQMFFDNRKFFRFRDECRSIGIDVPVIAGIKP
ISALNDINLLPQTFHIDMPNDLVVALRKCTNDNEAREVGIEWAVQQSKELIAEGVPGIHY
YTLGRSDNVARIVKAAF
>A0A0M5L3P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium breve|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQAVGEFNHASDLV
SYIRSVKPDLKVFGACYPEGHYQADTIDQDIENLKIKVDAGATHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>I1RSK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDAEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSVEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFNGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLERLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAVYPEWEATGLEAGGRAEAVNTRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWDYPKTRQDINDLFVKHIQGELSAIPWSE
EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PANEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGSTEASPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNLIHHDY
VNRDALWEVLSS
>A0A178VC94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabidopsis thaliana|TrEMBL
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGSTA
DLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEADGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMNL
GLIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPHGRWGDSHSA
AYSTLSDYQFARPKGRDKKLQQEWVVPLKSIEDVQEKFKELCIGNLKSSPWSELDGLQPE
TKIINEQLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNYINGDIFSVFA
>A0A5U9QC06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Albany|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8D8KIW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Culex pipiens|TrEMBL
PVFCSLPWISDNNLQYQRFVDTPMLKMTAKIVPHSSCLNHLSCYNITETQVDKFVDMGNW
NLFVIRGDTVSEGQRFQHSCDLVEYLRAKNNPDLTIGVGGYPYGHPESPSVDYDVKYLKQ
KVDLGVDFIVTQTLYDAASFLAYVDECRRAGITVPIVPGLFLPGSPDQLETVLALTRVNP
PAGVRELLQSHAHDEPDQFEAFVVKHFA
>A0A0S7LLL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poeciliopsis prolifica|TrEMBL
MCRVLLDSGKVPGLHFYTLNREVATLEVLRQLGLWVEDPRRPLPWAVSANPKRKVEDVRP
IFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEE
LKNEQSVFEVFTCYITAQPNKNGQKVLCLPWNDEPLAPETNFLKDELEKVNRRGVLTINS
QPNINGKPSADPVV
>A0A359JJQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKIIDILNKKTMSLSFEVFPPKKETSFESVKETTEKIAESKPAFMSVTYGAGGGTSRFTL
DIARTIEEKHGVPTMAHLTCVSSSKDLIHNKIEEIHSMGIENIMALRGDLTPELENTDRS
KWDYRHAVELIREIKESGYDFCIGGACYPEVHPESENQREDIKHLKEKVDAGADFLVSQM
VFDNNLFYNFLYKIREAGIMVPVIPGIMPITNAIQVEKAIKLSGSFMPQRFKAIVDYFGQ
DPESMKQAGIAYATDQIIDLYANGVTNVHVYSMNKPDVAEAIMHNLSNILWKDYGVK
>A0A4U8VTI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium indologenes|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIEN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEDQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKRHLKLLPQVFKIDLPEELINEVENAKNNEAVKQIGIEWSIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A6B1B8H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MLLLKDASGRRRLLQHAQWELIPLRNLAEQLPYLPPQSPVSVTASASKTLEDTLDLTAEL
CALGHHPVPHVAARMVTSRDHLEELLGRIESMGLSEIFLVGGDVASPAGPFDSAIGLLEA
LREVSHSLVHIGVTSYPEGHALITDAVLHEALHVKQVLLAEAGIEGHAATQMCFHPKAIL
EWLTAERDSGLNLPVHLGIPGAVDPARLLRIGTRLGVGASLRYLRKNTGAVARMLRPGGY
DPSGLVDRIAPHAERLDIAGLHVFTFNAIADTVAWRESALAETSSRRR
>A0A1B9N9Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sediminis|TrEMBL
MTGKDVPGLLEAQSAIPQGTRINVTFLGNEELEMRVTAAKAVKDAGFVPVPHVSARRLAS
QGQLEEFLTALQEVGASKHVFVVGGDPATPEGPYESSLDVIRTGLLPQYGVEEVSIAGYP
EGHPDISNELLWEHLTAKSASLKEQGLGSVVLTQFGFDTAPVMEWIDAVRDRGIDSTIRI
GTPGPAGIKRLLNFARRFGIGANAMIVKKYGFSLTNLMGTAGPDRFIDDLSALVAQDEKA
GEVGIHLYTFGGLKATADWAAGYRAKR
>A0A3S0NIJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium phaeovibrioides|TrEMBL
MLVKEILNTAHKPVFSFEFFPPKKDADWETLFETITALSPLNPSYVSVTYGAGGSTRTRT
HDLVTRIQKETGLSVVSHLTCIASTSGETGEILENYQSHGINNVLALRGDKPAGTESIAD
AVKDFPHAIDLVRFIKNNHPDIGVGVAGFPEGHPETPNRLQEIEYLKAKVDAGADYIVTQ
LFFDNRDYFDFVDRCRLAGISVPIIPGIMPVTSTKGMTRMSELALGARIPAPLLKKVLDA
ENDAQVASIGIEWATNQVQELIDNQIRGIHFYTLNMATATLEIFQNLHS
>A0A244DN54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia hospita|TrEMBL
MNPIELSFEFFPPKTQEGLDKLRATRAELLPLKPKFVSVTFGAGGSTQQGTLDTVLDMAK
DGLEAAPHLSCIGSSRESLRAILNEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRSEFGDWFRIEVAGYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DAHKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VADLCRRLVEAKVPGLHFYTLNGSAATKAICERLVG
>A0A356QVY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSTLSNALHSSEFVVTSELTPPKGLDLAPLLEKAGLLKPYVSAINLTESHAARMAMDPVA
VGHLMLDEGVEPIVQMTSRDKNRLAIQASILGACALGISNLVFMGGDSPKNGDHPDAKPV
FDLFASQLLEAVRALNNGADLNGNTLNQHTEIFAGAVVNPGATDPDAEIENLHRKINGGA
EFFQTQAVYDVNAFSAFLEKANSPKPILAGIIPIKSVKMAQYMNERIPGVDIPNHLIEKI
AAAGEDKDEIARISIEIAADTIRELRSVTKGIHVMAIGWEQHIPTMLEQSQS
>A0A351XI95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTSFEFFPPRTDKGKQTLAQVRQELSAINPEYFSVTFGAGGSTQDATLETVLDIQANDG
VSAAPHLSCIGSEKAKIIELLDQYKAADINRLVTLRGDIPSGVRDIGDFRYANELVEFIK
SEYNNHFHIEVAAYPEMHPQAKNIQTDLEHFANKIKAGADAAITQYFYNADAYFRFRDDA
QKLGIDVPITPGIMPITNHTQLVRFSNMCGAEIPKWILERLKLYENDLDSLTAFGTEVVS
NLCQTLKDQGVDSFHFYSMNRTEPSLSIAKNLL
>A0A450VG60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. H|TrEMBL
MNIQRSDTRVFSFEFFPPQTPEGQNNFRATWQRLSELNPHFFSVTFGAGGSTQSGTLEAV
IEIQRNSGIQTAPHISCIGSTRDKIRKILDSYLSVGIRRLVALRGDLLPGMDEAGEFRYA
NELVEFIRAETEDIFYIEVAAYPEVHPAALSAEIDLKNFKRKVQAGANGAITQYFYDLNA
YLRFVENCQRVGVHVPIVPGIMPITNYTSLARFSERCGARIPRQLAEQLEGFGDDLDALR
AFGIDVVTELCRQLLEAGVPGLHFYALNRAEPVMTIWKNLNLPQ
>A0A123TBC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVQSILHSLNEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARTIHQATHSLFKHYS
>A0A7C1QU04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MTLREKITMGQFVVTAEMTPPQDADGDIIRRKAVHFHKGVDGVNITDNQTAIVRLSSIAA
AKIALEEGLEPIIQMTCRDRNRIAIQSDLLGAAALGIENVLCLTGDHQRFGNHPEARSVF
DLDSVQLIAMVQRLTQGYFLSGETIKKPPALFIGGAANPFADPLGFRVIRLAKKIQAGAR
FIQTQPVYDLDRFQEWMEGVRAQGLNKKTAILAGIMPVKSLKALLHMENEVPGIRIPKSC
FTRMENAEDQNEEGVKMAVEMILALREIDGVQGIHLMPMMWESVTPRILDEARLLNR
>A0A6V7EH15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. pelargonii|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYACDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDT
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1Q9A3J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium taibaishanense|TrEMBL
MAHTSTKTGTRGFKLSFEFFPPKSEEMEHQLWATVDDLAGWDPEFVSVTYGAGGTTKAPT
LAAVRRLIGETGLATASHLTCVGATREEVAQVVEDFRAVGVKHFVALRGDPPTGVGSAYQ
PHPGGYENAAALVEGLKTLGDFEISVSAYPEKHPESADLSMDIDMLKRKVDNGATRALTQ
FFFDNDHYSRYLDRVHAAGITIPIVPGIMPILNLNQLKRFASMCGTSIPASLDKRFEGMD
DKPAERATVAAALAAEQIADLQARGVDEFHLYTMNRAPLVNATLEQLGLQRSDATVRNRA
GALA
>A0A4J1TBY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEEHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEYDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A323VNB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter versicolor|TrEMBL
MKRALTVRDGATRESLKRAINDLGFEVIPFKKTEQAVLDNVPKDVRLTVTASPAKGQDAT
IDLTIALAGHGYSVAPHLSAQQVRDRAHLTDVVARCREAGITDVFVVGGDPTDEPTGFKN
AHELLVALHELDHGFTDIGIGGHPEGHPSAPAELLFQALKDKAPLANHIKTQIVFDPKVI
LTWARELKNRGIDLPIHVGVPGAVHRQKLMRVSGGLGIGESAKFLKKQQNLLWRFFIPGG
YSPDKIIKGLAPHIGKPDNHLEGFHVFTFNDLAPTEAWRQQMLRDLA
>A0A5D2NTD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium tomentosum|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPGNDGVATPEAYQNELAYLKRKVDAGAD
LIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAA
L
>A0A5K0WDH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nymphaea colorata|TrEMBL
ICVETMMHLTCTNMPVDKIDHALDTIKSNGIQNVLALRGDPPHGQDKFVQVEGGFACALD
L
>A0A171KWN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kerstersia gyiorum|TrEMBL
MTSLSSQYAISLEFFPPRDLAAQERLVRTAKQLMALNPGYVSVTFGAGGATRDGTADTVR
TFANLGCEVAPHLACIGTSRADLSAILGAYREQGVRRVVALRGDLPSGMGSLYGEFRYAS
ELVAFIRETTGDWFHIEVAAYPEMHPQAESLARDMDHFVEKVQAGADSAITQYFFNPDAY
SDFVERAQARGVAIPIIPGIMPIVNNTQLTRFSQMCGAEIPRWLRLRLNDYADDRESLRA
FGADVVAQLCQTLLERGAPGLHFYTLNGSEAVRNIWRRLSPGEL
>A0A108GIJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia stagnalis|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATKTICERLGA
>A0A379Z6L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella flexneri|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A174LFN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusicatenibacter saccharivorans|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A1J5TW87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bathymodiolus thermophilus thioautotrophic gill symbiont|TrEMBL
MKTSFEFFPPRTEKGKQNLAQVRQELSVIQPDYFSVTFGAGGTTQDATLETILNIQKNDT
IPAAPHLSCIGSEKENIIELLDQYKAAGVNRIVALRGDIPSGVRDIGDFHYANELVEFIK
THYNEQFHIEVAAYPEMHPQAKNIHADLQHFANKVKTGADSAITQYFYNADAYFRFVDDI
EKLGINIPITPGIMPITNYAQLVRFSQMCGAEIPKWILERLKLYENDLDALSAFGTEVVT
NLCQTLKSQGVESFHFYSMNRSQPSLDIAKTVL
>A0A2X3Y6W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A6I3I0D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARISDLIAAGRTYSFEFFPPQTQAAQMSLGRAIAELSPLAPSFVSVTYGAGGSTRERTR
EVVTWVRKETDITPMAHLTCQGHRRSEIKEILDNYADAGVENILALGGDVPLDGEVQPSD
YTFASDLLDDVLADGRFSVGVAAHPELHPRSPDRATDRRYLAAKLGSSDFAITQFFFEVD
VYVRMVDELRALGVDKPVLPGIMPVTNKSQILRMAAMSGAAFPEWLAQRLEAFEDPEDIR
RVGVEAATELGQALLDAGAPGLHFYTLNRSTATREIYANLGLPIEQ
>A0A1V8UCH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rachicladosporium sp. CCFEE 5018|TrEMBL
MHITKKLAASHAKGEPTYSFEFFPPKTSQGVQNLYDRMDRMHGFGPAFIDITWGAGGRHS
QLTCEMVKVAQSVYGLETCMHLTCTDMETSKIDEALKEAYNSGCTNILALRGDPPREQEK
WEQAEGGFRYARDLIKYIKTNYGDHFDIGVAGYPEGCDETTGSEEHIPYLKEKIDAGGTF
IVTQMCYDADIFIDWVHRCHAAGIPESVPIIPGIMPIHTHASFMRRATWTQCHIPPEWHE
KLEPVKNDDVSVREVGKELVADFCRRVLDSGTTMHLHFYTMNLAVATRMVLEELAVTPPS
NEHNPLLKPLPWRQSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAF
GELDTYGVGLKGTNEENRKLWGSPESNRDIADLFVGYMKGSVKSLPWSEAPINTEANVLQ
SDLIDLNGRGLLTINSQPAVDGAKSNHQDYGWGPKNGYVYQKAYLEVLVHPNLIDTVISR
MERDEDITYYAVNSSGSLRTNVPVDCGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFY
HLGSEWAKCYAEGSASKTLIKDVVDNWYLVNIVHNDFRQARGIFPLFEGLSAPGLSVTEQ
ANGNGYVNGHVNGGAENSDLSFRKKPETNGVYDGNNAVNGADHANMTNGQNGEVEA
>A0A6L6D0B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSAGTAFDVSSATVQTPTISFEFFPPKDPEGEQKLWQTIDELQEFKPDFVSMTYGAGGGT
RDRTVRIAAEFIAKTGVPVIGHLTCVGSTRDELVDVLEQYKSEGFHGVLALRGDPVGGPT
APWVTTPGGFDYADQLVELAAEIGGFSIGVAAFPDVHPASDGNFAQDINVLLRKEELGAT
FAITQFVFDSGRYEALRNALDARGSKLSIYPGIMPVTSYPQIVKMLELSGGYMPKATRLR
FARYQNDPESLKQLGIDVAVQICEDVFALGAEGLHFYALNTAGPTAAIIKQLSMLAR
>A0A457RG42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A2T4KK94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus devriesei|TrEMBL
MSRLLKQLHNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVERIHRSYIQAGADIIQT
NTYGANFEKLKAFGLEHKVKEIHKAAVQIAKRAAKPDTFILGTVGGFRGLKQEDLSLSTI
QYHAENQIDTLVEEGVDGLLFETYYDLEELSNIVTATRRKYDIPIIAQLTASNTNYLVDG
TEINEAFKQLIECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIAYIKSSVKDLKPVSDKKVIPINRKT
NHSRTHTYKHNLTTKVKNGPTVIVELDTPKHLDTDLFFENVGKLDEANIDAVTLADNSLA
TVRVSNIAAASIIRQKYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAVTGDPSKV
GHLPGASNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMSYFITQPVYSKEKIKEVYEATKHLNTPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQRLDYSLELTAY
SKAITQNKEAIS
>A0A6N6JZT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter pasteurii|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A090B3A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVK
TGKEFTPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWKNSVVAK
VLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPIETRGTSSWKNWYLAIET
>A0A3V0MPV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A803KJJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pan troglodytes|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYE
EESPSRSIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELVNRPTQNARETEAP
>A0A3S0KWB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHISPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEHFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQTGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQSEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A3D2V1Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospina sp|TrEMBL
MKIIEKLNGSSPIFSFEFFPPKDSDGFATLFETIARLKPSAPAYVSVTYGAGGSTRAKTV
DLVGKIKNDIGIESMAHLTCVGHDEQEIRSVLESLQGQDIENVLALRGDPPQGEETFVKT
EGGFEYASELVSFIKNNFSFCIGAASYPEGHVECPDLDKDIENLQRKVDSGVDFLITQLF
FDNRYYFDFLDKVQKKNINVPMIPGIMPILNLKQIKRFTKMCGAHLSDSLMAKFEGVQDD
NEKVRQIGIEHAIAQCKELLENKVPGIHFYTLNRSKATLAILEELKEFA
>A0A358CYE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MAVSIFRSKELPGDKAHRVALLKQARFEVIPLKNLAAQLPFLPAASEVSVTASPAKSLED
TWSLSRELSKMGMKPIPHLAARMITGQDQLRMLIDQLPDIGASELFLVGGDAPEPFGPFN
DSIQVLEVILGMKHELTHIGVTAYPDGHSFIDSEVLSESLHKKEALLKGSGVEGHAATQM
CFDPRTIRTWLSEERKRGLKLPIHLGVPGAVERTKLLSIGARLGVGASLRFLKKNRATLA
RMFAPGGYDPDKLLRPLNPELKSLGVEGLHVFTFNQVQSTVTWRDEAIAGS
>A0A653KAH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter proteolyticus|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKTVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>J7EQB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nicotiana tabacum|TrEMBL
MKVIEKIQEAAKDENRVVFSFEFFPPKTEDGVENLFERMERMVAHNPSFCDITWGAGGST
ADLTLEISKRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKINGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDVIPANGIATQEIYENDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQLGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPEEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTLGWDEYPHGRWGNAQN
PSYGALTDYQFMRARSRDKKLQEEWAVALNSVDDIYERFKDYCLGKLRSCPWSELDGLQP
ETKIINEKLGHINTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSGEKL
NTLVEKCKAFPYLTYMAINKEGNWISNISQTDVNAVTWGAFPAKEIVQPTVVDPASFMVW
KDEAFEIWSRGWAQLYPETDPSRKLLEQVQNSYYLVSLVDNDYINGDLFSIFKDI
>A0A395XJT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea formicigenerans|TrEMBL
MTCKIRDILKDQTPQVSFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKN
TVSIASHIKDDFGVTSLAHLTCVSSTREEVHQVIDKLKEKNIDNILALRGDIPKDNAFPL
PNQYRYACELIEDIKQQGDFCIGAACYPEGHVETEHKKDDISNLKTKVDCGVDFLTTQMF
FDNNIFYNFLYRIREKGILVPVLPGIMPITNKKQLRRSMELSGTAVPQRFLAIIDRFGDD
PEAMKQAGIAYATDQIIDLIANGINHIHVYSMNKPDVAAAIMNNLSAILKIED
>A0A399WYQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MLEVTLLEALRERVLVLDGAMGTQLTALGYEGAPLALANLERPDIVRRIHDDYLTAGADV
IETNTFWLNSFRLSEMGCIADPVEICAAGARIAREAAGDRFVLGSIGPCGKPLIPLGPID
LEAAKREFVVQAEALLSGGVDGILLESFSDLEELLIAIRVVRPVCQLPLFATKSFIEDGE
TLAEGFPLRAAQRILDAGADGTGANCVVGPQRMFDIVRWMAEVGDAPIIAMPTPGMPQLV
KGEPVYDVTPAYFGEACARLAEAGANIIGGCCGTTPEHIRATVASLRDRRPRKRVHQLTA
EAESRRPIPESEPSRFSQKLGKEFVITVELDLPRGLDTDKVLHSSAVLHERGADLIDISD
GARARLRMTPVAICALIQNAVGIEAMMHVACRDRNLLALQADLLGAHALGIRNVLAVTGD
PANIGDFPSATSVFDIDSVGLVRILSRFNEGRDMAGNTVGRKCAFTIAIAFNPLARDMAL
ETDRLTRKADAGAHVIYTQPIFEKAHLDAACEAARRVGLPILIGVMPLRNRRHAEFMHNE
VPGIEIPDWVRARMGEVSEEAAPEVGIEIAQEFAQCLPGRANGMYVMPPFGNPTVAIRVM
EAIGR
>A0A8B8UA96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Camelus ferus|TrEMBL
MVNEPRGNGGPNPRSEGSSSGSESSKESSRCSTPGLDPERHEKLKEKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYAADLVKH
IRGEFGDYFDICVAGYPKGHPDAESFEADLMHLKEKVAAGADFIITQLFFEADTFFRFFK
ACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCRELLESGLVPGLHFYTLNREVATMEVLKRLGMWIEDPRRPLPWAISAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GKELTSEESVFEVFVRYLSGEPNQDGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETTEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGKLYEE
ESPSRMIIQHIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRAPQNEREMEAP
>U5H9V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbotryum lychnidis-dioicae (strain p1A1 Lamole / MvSl-1064)|TrEMBL
MVKISEKIAKAERDGRPWWSFEFFPPRTPDGWANLYDRIERMKQLGPIFVDITWGAGGAT
SEATTTFVKHAHSELGLETCMHLTCTNMPVSMVDAALKDAYDSGCRNILALRGDPPRGSE
EWVQTEGGFNHAIDLIRHIRKHYGDYFDIGVAGFPEGHPQAESAELEMKHFKAKIDAGAN
VVFTQMFYDANVFINWGRRVREAGITVPIVPGIMPIQTFASFKRRTDFAKTIVPQELWNL
LEPIKDDDLKVREVGTKFVADMCRKVLTAGIGINGIHCYTMNLSRGTEMLLEEMNFVAQA
DIVKPLPWRVSLTQKRRTETTRPIFWSNRTRSYLSRTADWDEFPNGRWGNQASPAFGDLD
SLALSLPHKAQDATTLWGEPTSFGDVAQLFARFCTGDLKALPWSDQPVARETTVISEPLK
KINSAGFLTINSQPRVDGAGSSDPVHGWGPRGGYVYQKAYLEFFASSAHLEDLLKVLQRY
PSMTYHAVNKAGDLQTNAAPGPNAVTWGVFPSAEVIQPTVVDGTAFLAWKDEAFELGTLW
AELYSKTRQESAKVISEIFDTFYLVNLVQNDYRNVDELAIFKPFFEVIDGTKTATANGVN
GSH
>A0A0F7RZC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporisorium scitamineum|TrEMBL
MASASAVFPSAGAGSSDPAHITSKIHAASSRDAPFWSFEFFPPKTTQGLANLYNRIARMR
ANLDPSWIHVTWGAGGTTGGKSLELAGRIQKGKLDPDVQVVQKQVKQIGSGAQQHIDNVK
GGESWEQSGPDACDVCLHLTCTNVEKSSLDETLETAKRLGIKNILALRGDPPRGEEYWVA
ADEHFQHATDLVRYIRQQHGDFFCIGVAGYPEGHADYVDRDVKRDLRYLKEKQDAGAQYI
VTQLFYDVDQFLSWYKDCRDIGITIPILPGIMPIQNYSSFRRMTNLCKVRVPQLILDALE
PIKSDDAAVKEYGVSLSIHMVGRIFLESDIRGFHLCSLNLEKNIERILEGLGWKTDLGAQ
LETDARLRGIPARLHLEATKNQMLSDRTGANTPKDFKVTTQEALARTLARTSSSYQVPET
STWDEFPNGRYGDSRSPAFGEMDGYGVSLKVPPQDALRIWGHPVTLVDISKIFASYLEEK
ISCIPWCDAPLMNETLQIRDRLLSLNRLAEGATQSGKGWWSVGSQPAVDGAPSTDPTVGF
GPPGGFIFQKSFVELFMSTADKDKLVARIDALGANAQITYFAGNAQGDFQSNLGDGEANT
VTWAVFPGKEIVQSTIIERESFEAWRDEAFEIWGEWSLLFPKQSASRKLIEEIKDGRWLV
TVVHHDYKQKEALWHFLAE
>W6I2P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulibacter bethesdensis|TrEMBL
MTTPTGFSLPVRGDGWRQRDMNRLAGQEQQGASATLRRWLTGPRVTGLPAMDAEHPVPLL
SFEFFPPKTAALERQLWSCIRRLEPLGPRFVSVTYGAGGSTQARTHETVARIVRETSLTP
AAHLTCVGATRDEVDEVARHYWEAGVRHIVALRGDMPGGAPYQPHPGGYAYASDLVAGLK
RIGDFEISVAAYPETHPAAPDAGFDLDNLKRKLDAGATRAITQYFFDTDTFLRFLDRCLV
AGITAPIVPGIMPVSNYAQAVRFSTAIGTSVPDWLGRLFDGLEDDVETRRMVAAVVAAEQ
VRLLQANGIDEFHFYTLNRPDLVYAIARILGVHPPAAPVA
>A0A4T0SBM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia mellicola|TrEMBL
MKITEKLLAAEREDRLWWSFEFFPPPRFVDLSTTISAHSVQGMTNLVDRIERMRRLGPEF
VDITWHSGGRTAELTTELVKTCQASIGVETCMHLTCTGMPREKVINALEEAKKNGCTNVL
ALRGDPPRGQTEWYPHPNGFTYAADLVRHIRQEYGDYFEVAVAGFPEGNLQYKHSSDKDN
EIQYLKEKVDAGADLIMTQMFYDVDNFIDWCNKVREAGVTVPIVPGIMPIQTWNGFQKAV
QMAQTKVPQDWMDQLEAVKEDDAKVREVGTKLVSDMCRKILDANVGIRGLHLYTMNLERG
PKMILQELNLIPQTQILNPLPWRPSLTPTRRAENIRPIFWANRQKSYLSRTEMWDEFPNG
RWGDSRSPAYGEIDGWGPTINFKLDEAREIWGEPLKYDDVCNLFSRFCLNDLKALPWSDQ
PPARETSVIDRQLAMMNKIGFFTINSQPAVNGARSDDPVHGWGPKGGYVYQKAYLEFFVS
PDNLDKLISRIELNPMMTYYAVNRRGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVS
FMAWKDEAFELGYQWSDIYEKGSTSQQLIKDIMDSHFLVNVVHNDFKNGQDIFKPFLDEI
ANESAIKDTTKN
>A0A6A4DL13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora fragariae|TrEMBL
MKIIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMAEADIRKALDQAKDAGIQNILALRGDPVRGATS
FDECDRGFSHAVDLVRYMREHYGDHFCIGVAGYPEGHMESSDKKADVQYLKEKVDAGADF
VITQLFYDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTAFCNTFVPQEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRIVEGLSSLSSRVPR
RELPWQTSTLSKRAAESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSSTSTPNERRAMWGEAPAAKEDIRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGVLSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
PSVQYHAVNLNGHSYSNASKSAIAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEDGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSPATSP
>A0A3M6YY78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGVRNILALRGDPPRSDE
YNDPNNPLSEQDDSNRDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLVEKTAAGADFIMTQLFFDVEAYNDYEKRLRSHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLNRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTL
NLEKVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSS
NRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPVNSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLQGEIEA
MPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSNDPIYGWGPKNGFVFQKPF
VELFLPSADWQRLKPILQADDQVTYYAGNAAGDFQSSDENSVNPVTWGTFAGKEIITPTI
IEGDSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDA
LIAA
>A0A6P5X3Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Durio zibethinus|TrEMBL
MKVIEKIQSVQDDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGSGGST
ADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDAIGSNGVATPEAYQNDLAYL
KRKVDAGADLIITQLFYDTDIFLKFVNDCRQIGISCPIVPGIMPINNYKGFLRMTGFCKT
KIPHEITAALEPIKDNEEAVKSYGIHLGTEMCRKILAHGIRTLHLYTLNMEKSALAILMN
LGLFEESKISRCLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDHYPHGRWGDSRN
PSYGALTDHQFMRHRARDKKLHEEWVTPLKSIDDVQEKFKNYCLGKLRSSPWSELDGLQP
ETKIIHEQLGRINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSMEKL
DALVNKCKAIPCVTYFATNKNGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFMVW
KDEAFEIWSRAWCALYPEGDPSKKLLEEIQSSYYLVSLVDNDYIGGDIFSAFEDL
>A0A536D5P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIAEMLARGRPTVSFEFMAPRDENEVAVVERTTAALAGHAPDWVSVTYRKATGHKTLEL
VTRIKRQYHIEAMAHLTCANTADETRPILNWMEREGVANVLALRGDPPGPGEAFVPADPH
FQHGSDLVAFLRRSGYRFGIGAACSAEKHPESPDQAHEFRYMQLKVDSGADFLITQLFFD
NRFYFDLVRRAKEAGITIPIVPGLMPVPSRRSLAFMAAMTGASLPPDLARAIEEAPDDDA
VRALGVRHCIEQCVELLEAGVPGLHFYTFNRARAPMEILASLRGQQLLTA
>A0A3Q9I2L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomicrospira sp. S5|TrEMBL
MQSQQQYEQKISLEFFPPRTEKGMEKLKTVIQELSPIQPEYMSVTYGAGGTTQSRTIDTV
RYIQTETDNEAAPHLTCIGASEESVLELLDTYEAMGIKRIVALRGDLPSGMMDPGEFKYA
SDLIAFIRRERGDTFKLEVAAYPETHPQARNCNIGIKWFKHKVEQGADSAITQYFYNVDS
YLYFIDNCERSGIDLPIVPGIMPITNYENLVRFSEGCGAEVPRWLKCRLESFEDDQESLL
AFGEDVVTELSQRLLDAGAPGLHFYSMNQSKPVLNIVNQLTFKDR
>A0A718ZFV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium (strain SL1344)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7D9HV13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paramuricea clavata|TrEMBL
MHIAGTILDYCGVEIMLHITCANETRETITRHLYKAKSMGIRNILALRGDPPHGEDFEVV
DEGLVYGTDLVKHIRQEFGDSFTICVAGYPQGHPDCSSYEEDLIHLKEKVDAGADFVITQ
LFFETKTFLKFVDDCREIGIDVPIIPGVMPIQSYDSLRHLVKLSKLSIPQDLLDAIQPIK
DDDKAIRNYGVDYTVKMVNELFSNGVPGIHFYTLNREVATTEILKQTSLWSLEPLYARSL
PWKPSANVKRIKEEVRPIFWASRAKSYVHRTSEWDEFPNSRWGDSAAASFGDLSDYHLFY
LRNRTKKETLLKMWGEQLTSVQDVYDVFVCYISGEKNVNGTKVTMLPWNEDELAPETSEV
SEDLVELNRKGVLTINSQPHANAAKSTDPVFGWGGAGGYVYQKAYLEFFTRKEVVDKLLE
VLGTNYPSVSYHVVDHTGEVDTISEDLASPVAVTWGVFPGKEIIQPTVVDPVSFQIWKCR
CCAASFKWLDRNIIADFREESSFQISHLVVARVYKATFFTLHRVTEAFFLQCPPLRWNKW
AT
>A0A6B1BSA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MARIVDLLSAQNTLSFEFFPPADDIASKQLDETLDELAGLSPSFVSVTCGVGGDGHDRTH
DIVTDICRDRTFPAMAHLTCVGHTREGVAALLDDYAAAGVANILALAGDPPDGSAISGDF
HYASELVEVIRDHPADFSVGVAAHPEVHPRSTNRASDRQHLAAKLSRADFAITQFFFDPA
DYVQLCEELADLGCQQPVIPGVMPVIWPKSIRRFADMNGSTVPEDLFTRLESMPAPDRIG
AAAESAAKLSQTLLDAGAPGIHLYTLNRPEASTQITELLNL
>A9RW65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Physcomitrium patens|TrEMBL
MKVIDKINNGLAGGNVVFSFEFFPPKTEEGVENLFDRMDRMVRHQPAFCDITWGAGGSTS
AITLDIANKMQNMICVETMMHLTCTNMLVETLDNALDNVKSNGIQNILALRGDPPHGQDK
FVTIDGGFSCALDLVRHIKDKYGDYFGITVAGYPEAHPDVIGEDGIASEEAYKKDLAYLK
EKCDAGGEVIVTQLFYDTDIFLKFVNDCRQIGIKAPVVPGIMPIQNYKGFLRMTSLCKTK
VPAEIMATLEPIKDNDEAVRAYGIHLGTEMCKKILAHDIRTLHLYSLNLEKSVLGILQNL
GLIDFSKVTRPLPWRPPTNSKRTKEDVRPIFWANRPRSYISRTTSWDEFPRGRWGDTGNP
AYGSFSDHQFLRKKTRSKKLQKEWAVPLNSCEDVNQIFAKYCQGTLSTHPWSELEGLQPE
TSQINDKLVALNTQGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSPEKLQ
AVIEKAKSNPSLTFIAVNAKGETQSNIGPNCVNAVTWGVFPAKEVIQPTVVDPVSFMVWK
DEAFQTWDHEWAALYSEEDSSRKILSEIKDSYFLVSMVDNDYINGDLFAVFATL
>A0A5W0W8F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Typhimurium var. 5-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2E9NFZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MAHATPTTESAKRLVEGYSLEITGKEKDVVGLTEAASLIPAGTKVNVTFLGNEDLPMRVA
AAKAVKELGFVPVPHISARRIASQAQLEEFLSALAEIGATEHVFAVGGDPATTEGPYPDA
LTMIRSGVLQQYGVKEVSIAGYPEGHPDIATDVLWQHLEDKSAALKDAGLDAVILTQFSF
DTDPVMAWIKGVRDRGIDTQIRLGTPGPAGIKRLISFASRFGVGANAMIVKKYGFSLTNL
MGSAGPDKFVSDLAALFDADPSVGAVKLHMYTFGGLEATATWARDFIAK
>A0A1H3QVE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas salomonii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITQMCEQLLQGGAPGLHFYTLNQTEPSLAIWNNLKLPR
>A0A1D8UQ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kozakia baliensis|TrEMBL
MSRIAVELVPRDNETLLRDFEVVRETAPEVSAINLPDLLRMPVRSWEGAATLRAAGPLPI
IPHVRAIDIAPGAPLPGAEDEGLREVLIIAGDPPPDETHRVYPNTSEEIIARYRREAPHL
TVYGAFDPYRRAPYQELEALQRKRDAGASGFFTQPLFDRRLLELSASWLEKDTVFWGVSP
VIGPKSRAYWERVNHVVFPSDFEPTLDANIAFAREVLQFARARNDNAYLMPLRVDLAKYL
TPLRDAMR
>A0A1X1A3Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREKNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFFTLQLGF
DAAKHQEAIHWMYRQASPKPMLACLMSLTHGRATMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALEARIEHWQTQLQSLEQWTPA
WHASWQMPGLPAVTFHPPQAGWRLGESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPLWATRAGAQVLHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A0E0D8P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryza meridionalis|TrEMBL
MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVHHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLK
QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNL
GLIEESKISRPLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLD
QLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWK
DEAFEIWSKGWACLFPEGDSSREILDKVQKSYYLVSLVDNDYINGDLFAAFKEI
>A0A508AQI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter maris|TrEMBL
MSADQAQDTAMTPISFEFYPPKTDEQRSQLDRTAARLKAHAPEYVSVTFGAGGSTLSHTP
EAIQRLAGEHGYSAAPHITCMGGSRQEIRGLLKLYKAMGARRLVTLRGDLPSGMVSPGDL
RYANELVEFIRAETGDHFHIEVAAYPEMHPQARDAHADLGHFKRKVEAGADGAITQYFYN
ADAYFRFVDDARAAGIDIPIVPGIMPISNFSQIRRFSDMCGAEIPRWIAQRMLAYGDDAA
SVRAFGADVVAQLCQRLIDGGAPSLHFYTLNLAKPTQSVIDRLA
>A0A2K4AIM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus schweitzeri|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFSHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A1C5TXH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MGMLEKALEGGKFGVTVEMAPPKGYDFTEQLAVAELLKGKVHGVNVTDMQSACLKASSLG
LCIKLKEAGLEPIVQVTGRDRSRMGIMGDMLSAAAFGIDTMLALTGDHPTVGDCKESKPV
YDLDSVGILHMLTYMEATGKDCGGNDLDNAPTFYKGAAVTPVYDPLPLQINKLRQKVDAG
AQYIQTQGIFDIEGLKRFMDEVDKANIHTHIMAGIIPLKAAGMAKYMNENVPGIAVPQDM
IDRLSAAAAEGKEKGVKGLPTQLGIEMAAEMIAKIKDEGICDGVHIMAIGAEKNVPKILE
KAGITIE
>A0A6B3W2J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus aquiflavi|TrEMBL
MSLRKALKERILIGDGAMGTLLYSHGIDRSFEEITLSHPEEIYHIHKAYIHAGADVIQTN
TYGANVIKLSRYGLENKVNVINQEAVRIARKAAGRETFVLGTIGGILGFNKQEIPLNDIT
NSFKEQLYSLLEEGVDGLLLETYYDLEELTAVLAIARLETNLPIIAHVTMHEPGVLQNGL
SLTQALTQLEGIGADVVGVNCRLGPHHMIRALESVPLQQKAFLSAYPNASLPDYEDGKLT
YTAKEDYFKKCAIAFRNEGIRLLGGCCGTRPEHIKAFAEGIKGLRPLQEKVIKQKEKRKD
ILIKPILQETPLFKKVMKERSIIVELDPPKHLNTNQFFAGAEALKKAGIDALTLADNSLA
SPRISNSAIAAILKKDFDLKPLVHITCRDRNLIGLQSHLMGLHTLGLNEVLAVTGDPTKI
GDFPGATSVYDLTSFDLIRLIKQFNQGISFSGKSLKQKTDFRVAAAFNPNVNHLDRAVQR
MEKKISSGADYFITQPVYDSNKMIQIKEATKHIKAPIYIGIMPLTSARNAEFLHNEVPGI
RLTEQIRSAMANKAHDPEQSRQEGIAIAKELIDTALEHFNGIYLITPFLRYEMTVQLTNY
IKEKSVSATEGMNVSGYTV
>A0A3T2WG51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Orion|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3E2E8P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia marcescens|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLRDIATDYWNSGIRHIVALRGD
LPPGGGKPDMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A100PTF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1S0ZR14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATGDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDIYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J6S6Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MEQMTVSVEFFPPKDDAGETRLWEASSALETIAPDFISVTYGAGGSTRDRTIAITKEITK
RTGRGTVAHLTCVGSTKAELIEILNQYKSAGIKSILALRGDPVGGPTANWVTTAGGFDYA
DQLVELAVGQGGFDVGVAAFPDGHPASSGDFSRDIDVLIRKEQLGATFATTQFFFESSKW
ENLVSKLGARGSKLPVIAGILPITNVKQLQRMAELGGTPIPDKISKLFSEISEDPDAVRK
AGVELATKLCEEMIALKVPGLHFYTMNTAAPTLEICANLGITARG
>A0A0T5P4S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius indicus|TrEMBL
MTGMSDDLSISFELFPPKTDAGITRLGDTVSQLSAADPTYFSVTYGAGGTTRDTTARVVE
MVAGQTGRPVAHHFTCVGASRAEIDRQAEGFWENGIRKIVALRGDLPEGETVPDDGYHDA
AELVAALRKVGDFDISVAAYPEVHPEAKDAGADLDHLKRKIDNGAARAITQYAFDTDTVL
RFIDRARAAGIDAPIVPGIMPVANFGGLKRFSEGCGATIPDWLGQMFDGLDDAPDTRAMV
ATGVAAEQCRRLIEEGVTEFHFYTLNQPKVTLAVCRTLGLTPDIPAEDAA
>A0A7J4QKA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon|TrEMBL
MKKITDILKKRFTRSVELVPPRNGTDPQVVWAALEELKSIPVDFISVTKGAGGSLRGGTT
PICHLGRERYGLTPVAHFTCREITARQVESELVDHHYFGIRNILALRGDPPEMSDEAEWK
GDYAYAHQLVSQIAAMNRGEYLCRRGKDDESASFHEGIPTDFCIGVAAHPEGQEDNVQHL
KEKVDAGAEFAITQMVFDVNLYASFVSACRKEGIAIPIIPGIWPLDKKWKILAAQEKFGA
TIPKPLAQRLLSQDDHEEFRKNGMLATVELCRAFKQAGAPGVHLFLFLDAVLAKEIFSQL
>A0A7H2SKG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKTQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLESAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A0D6IR75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J6Y609|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRRPFSFDTPNGKPIFSLEFFPPKDEKGEANLWVELAELNSLQPEFVSVTYGAGGSTRER
TVRITSEITARTGLRTVAHLTCIGSSKNELSEILDQYWQAGIRDILALRGDPPTGPQSEW
IPTAGGFSHSDELVSLAAAANFNVGVAAFPDCHPASNGDHLKDISVLLEKERRGAQFATT
QFFFSTDKYYNLVNELKERGSNLPIFAGILPITQVKQLNRMAQLGGTPIPANIVQKFSRI
EDDPEKVKALGIEIAVNLCEELIAMGAPGLHFYTMNNAYATKEIVKRIGLR
>A0A6J6JW00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTHISDLLAAGRTCSFEFFPPKTDDAARALEQTIAELEPLDPSFVSVTYGAGGSTRERTR
DVVINIERNIGITAMAHLTCVGHTRAQLDSLLDEYKAAGVSNILALAGDPIVDDNGVVAE
SEFEYAMELVELIKEKGGFSIGVAAHPEGHPRSADLYSDRRHLADKLNVADFAITQFFFE
AEPYLRLVEGLSAFGCDKPVLPGIMPVTNAAQVVRFAELAGAAFPPHLAARFDAIADDPD
AVRALGVELASELCQRLLDEGAPGLHFYTLNRSTATREIAANLGLGDASSAGE
>A0A316NRG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Gastranaerophilales bacterium|TrEMBL
MKLGKIYNSNKPVISFEVFPPDNDEKIQELYSEIKILMKCNPQFISLTYGAGGKNNENYQ
KVLKALKTDLKADVMPHFTCMCSGKSFIEENLEFLKSAGIENILALRGDIPQEIEKICTD
FCHANELVEYLKKKTDFSIAVAGYPETHIESASIEDDIKYLKQKVDAGAEVIITQMFFDN
EKYFKFCEHVQKAGINVPVIPGIMPVISNQQLLKMTKLARITIPKNFKDKLEKHFSDKDY
MKELGIEFATGQCQALLDKKVKGLHFFTLNKSYSTVKILENIL
>A0A442HN58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHLLHDEITETQVDMVK
TAH
>A0A3Y8PM78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella virchow|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A832VKT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosotenuis sp|TrEMBL
MTIRYEINPPRVIQDGVLSHKQVKGLLSKVEKRIISASKFCNGIHLTDSVLGVPRISPIT
TGAMIRHKLNLEITASIRVRDRNITAMTQSIYDAVLLGLDGLLILQGDEPPAGPKNSGLV
PSEVVKHFTKQGFGKNLDFFLSISAEPDFEKINKKLEAEPTGFVTQVIQSPDQVHRLVDH
LKPLGFKVIPCVMIPSQKNSNSAKMVGVDFSKYEEKTLDFIKEIHSSAKDILITSPNDSK
AALKILSQIKGLKRK
>A0A817F8T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood2|TrEMBL
MEFTLSDNQTVSDNQEIYTDEIHCQTAYNLNRFKRIESEGANLGAKGCSLQPVKYVSLTE
KILKRIADNDRWYSLEFFPPRTPSGAANLIGCFDRMAAGQPLFCDITWHPAGDPASNKET
SSMMIANTMLNYCGIDTMLHITCYGAKKADMLEYLYKAKDCGIRNVLALRGDPPIGEEWD
PAKSDFRYALDLVKFIRQHFGDYFVICVAGYPQGHPDSTSYADDLGYLKEKVDYGADFII
TQLFFQPETFIKFESDCRAIGITCPIIPGILPIQGYSSLRNIVRLAKLDVPKEILACIEP
IKDNDEAIRNFGVQTCLDLCRVLLDSGKVNGLHFYTLNREYATIEILKRVGLWLEEQPLR
ALPWKKTSFSHARSKENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGVLADYH
LFYMKLDATRDELLDEWGRELTCEQDVWQMFACYIGGEKNRLNKVVRHFPWTDEELSSET
TLIQKDLVNFNKRGILTINSQPAVNGKPSLDPIVGWGTPNGYVYQKVTITVCNLIADNIP
ALQAVLKNFPSVNYHFVNKSGGVNETNADDEQPIAVTWGVFSGREIIQPTVVDPVSFMIW
KDEAFSLWTERWSKLYEPESRSHEIIDKIANTYFLVNLVDNDYPQGSCLWQVLDSMFEYQ
KLSNKHVDS
>A0A847IYN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus chungangensis|TrEMBL
MRITDIYREKNLQKKSVISLEVFPPKTDAGIETIYQTVSGLTHKPDYISVTYGAMGSLGR
ENKTLEIAEKIKKEYGIETMHHLTSINNHPEQITEILAEIKAKNVQNILALRGDLPKNTD
VTGCPDIYHYAHELITDIKKAGDFDIAAAIYPEGHVDSPLDVENIEHVKRKYDAGANFFI
SQLFFDNDKFLRLNDYVKNSGIEAPIAAGIMPVLQESQVARMLFFGASLPTRLIKIINKY
KDSPEDLQKAGMDYACKQIDDLLARGVDGVHIYTMNKPFVANTMMDRYL
>A0A815KUB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria magnacalcarata|TrEMBL
MEFTLGDNETVPGDCKMHAHETHLESIHNLNRLKRIESEGANIAGKICSLQSAKYVSLTE
KISKRIADNDRWFSLEFFPPRTPSGAANLIGCFDRMAAGRPLFCDITWHPAGDPAGNKET
SSMMIANTMLNYCGIDTMLHITCYGAKKTAMLEYLYKAKDCGIRSLLALRGDPHVGEEWN
PAKSDFRYALDLVKFIRKHFGDYFVICVAGYPQGHPDSTSYEDDLAETFIKFESDCRSIG
IKCPIIPGILPIQGYASLRNIVRLAKLDVPKEILACIEPIKDNDEAIRNFGVQACLDLCR
TLLDSGKVNGLHFYTLNREFATIEILKKLGLWLDEQSLRALPWKKTSFSHARSQENVRPI
FWSIRPKSYVHRTSNWNEFPNGRWGISSAPSFGVLTDYHLFYMKIDATRDELLDEWGREL
TCEQDVWKMFACYIGGEKNSIDKVVRRFPWTDEELSAETTLIQKSLVEFNKRGILTINSQ
PAVNGKSSSDPVVGWGTPNGYVYQKAYLEFFTSAENIPALRSVLKTFPGVNYHFVNKSGE
VNETNTDDEQPIAVTWGVFAGKEIVQPTVVDPVSFMIWKDEAFSLWTERWGKLYEPESRS
HAIIEEIANTYFLVNLVDNDYPQDSCLWAILDSMFEYQKLPKKNIES
>A0A838E7U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euzebyales bacterium|TrEMBL
MTDDLRRSLERARFEILPLAGVSEQLDHLPANSVVTVTSSPTKGIDATLDLCERLGGRDL
RVVPHLAARLVRGRGHLAELLDRVEGLGIREVFVVAGDAKDPAGPFEGAADLLRAMAGIG
HALDEVGITGYPESHAFITDDTTIRVMSEKAPFATYIVSQICYDPTVIAGWVGAVRRRGI
TLPIHVGVPGVVDLARLGRISLKVGLGDSVRFLRKQTGVVARLVAGYTPDELIHGLAPLV
TEAGNGVRGWHIFTFNEVARTERWRQDLLRQIDGVRA
>A0A838SQR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euzebyales bacterium|TrEMBL
MIKPDGAALTESLRRARFEIIPMKGIDAQIPYLPREATVTVTSSPTKGIDATLELAQRLR
RDGFHVVPHLAARLVAGGGHLRDILDRVEDLGISEVFVVAGDAKEPSGPYEGASDLLRAM
ADLGHRLTDIGITGYPESHSFISDATTIQAMYDKAPYATYIVSQICYDPAQVAWWVGAVR
ERGVDLPIHIGLPGVVDRARLMRISLKVGLGDSLRFLRRQGGVAARLLGGYSPDDLVTAL
APTVAGGRGNVRGWHLFTFNEVEKTERWRQQMLSRYSGAQQA
>A0A6L6ISJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. DK608|TrEMBL
MTTPAISFEFFPPKNLDQSFRLWETARALAPLGPEFVSVTYGAGGTTRQLTHEAVTALST
HYGLNVAAHLTCVDATREETMQIVADYAAAGVHEIVALRGDAPQGQDRFAPHPDGFANSI
QLIEAIAARGDMTIRCGAYPEPHPESPDTSADVAWLKRKSDGGATSAITQFFFDADTFFR
FRDQAERAGVTARIIPGILPIQSWAGTRRFAERCGTSVPQWAEDAFAAAGKAGEAQLALE
TCVRLCQDLVDGGVDILHFYTLNKPELVLKVCDAMGVAAKPELAA
>A0A3A4KAV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MISRDEFAKRLERRPMLADGAMGTLLYERGVFINRSFEEACLSQPALVRQIHADYIRAGA
ELIETNSYGANRLKLKNHGLEERVAEINAAAARLAREAAGTETLVAGAVGPLGLSDPAAD
RPARPEMEAIFEEQIAGLIEGGVDLFILETHYALEELEAALAAIRRRSGEMPVIAQVTVR
EDGYSSHNLSLIEAIRRLSRLDVDMVGLNCTLGPRLLLDQVRQMAEIAAKPMSAMPNAGA
PTVVEGRYLYMSTPEYVAGFAQKYIELGVRLVGGCCGTNPEHIRQMGGFLASRAAGRVEV
LRSSEKDAGREQAQPKEPLPAWRKSPFAYKLRKSKRYVTSVEVSPPKGADLRAVVEKVKQ
LQAAGIDVINIPDGPRAVARMTPVALGSYLERVVGMETVLHYTCRDRNLLGMQADLIGMN
ALGVRNVILITGDPPKMGDYPNATGVFDVDSIGLARILQQLNRSLDMGGHELAQAPVLHY
GVGCEPGAANQERETARLAQKLEAGAEFIMTQPVYDTEMLANFLARADVGDTPILVGILP
LASYRNAQFLHYEVPGMRIPDPIRERMKAAGSGAAAQEEGVRIAREAVEAAKDLPNVRGF
YVMPPLGRYHLALDVLSPVRSGGEQSNYEI
>A0A2H9NDZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeum sp. CG_4_8_14_3_um_filter_33_2054|TrEMBL
MSLLRENFSRKFTATGEVSPPPCPDKTLFAREVEEMKPLMGRILGVNVVEGPGGRVLMSS
LGASIYMIQHGVEPILQQVVRDKNRVALQNDLISASIFEIENVLSIAGDHPACPASDNPK
SKPVYDMDSTTLIVMLKKLNEGKLWNGKDTNYENKNLNAKTNFFIGTGLSPTSSPLDGEI
YKVKRKLIAGCDFFQTQGVFDIEPIINFLNLYEKTIGEKISDKILVGIVPIWSYGMMKYL
LTLPGIVIGEKFRNDVNEARKKQKETGQKGLIEEIGVNLCVDLVDKIKGLGVKGVHIMPV
GNLHAMKEILDKSGL
>A0A838SUG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euzebyales bacterium|TrEMBL
MQRTVRELLATGQPSFSFEFFPPKTDDGWNQLWRAIRELEPLQPAFVDVTYGAGGTTRDR
TVEVVRRIAEETSLTVVAHLTCVSATKAEIREVVDELGAAGIRNILALRGDMPGDPSAAF
RPTPGGLDYAEDLVRLLKASGDFCVGVAAFPEKHREAPDIDTDAKFLAQKCAAGADFAVT
QLFFHVIDYVALVERLRRLGCDVPVIPGVMPVTNVRQILSISKLSGAAFPPDVAQRLQAV
EDDPDAVRAIGVEVATQLCRQLLAAGAPGIHFYTLNRSTATREIYESLHADLA
>A0A8F6LKZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter junii|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDHIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIQRFVEKVQAGANAGITQFFFNPDAYFYFI
ERLAKSGINIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1B9EKT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PTY087I2|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKA
TQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGPWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A427DNC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. v388|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLLNVARQLAGYNPDFFSCTYGAGGSTRDRTMNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLNQYRDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFDIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQQFG
EQVITDMCDRLLDGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A3A4KET8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MSFHQQITARNFLLIAEIDPPKGVNIKPFLDQALALKGRVDAVAVTDSEHAIMSMSPLAP
CHELLANNMDPLLVINGRDRNRISLQADLLSAWALGVRNVILKEGIDPAWGDQPLVRTSG
DLNLDVMAQAVSALNQGKDLGGESLNGGTAFAAGVGIDPSDDINVNRRRADALARYKEIG
VQFAVLGPTYDLNIIELFVNKAQDAGIRLFATLMLLKSVAMIRYLDGLAGVPSVPNEFLK
RLMDAPVKAQAGLEIAAEFMKDIEKLCSGAVLHALGWGPRLTELLTLIGR
>A0A4Y8US97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. HD19AZ1|TrEMBL
MTLVAEVEAPAPPPARAAGRRAEQAGALDRPTVSFELFPPRNPDAAPRLWRTVRELETVE
PDFVSVTYGASGRTRETTRVLVRRLLRETSLTPIAHLTCVGTSRDEVTTIVEEFLDEGVR
SFLALRGDPPAGEPDWRPHPDGVHTAAELVELLREIEGRRCGRSASQAVRARVRPLSVAV
AAFPRGNHATGGTRAQDVQALLAKQEAGADFAISQVFFDAEAYLGLVAEAREAGVTIPIV
PGIIPTTDPARLLRVQELTGVPVPQRLLDLLGGTDDPAERHRRGTRAGVDLVNGVLDGGA
PGVHVYTFNTHEAALDLLDGADLVGGRRTTVADPAPPTTTAPTTPAAPTGAASTTPRGNL
S
>A0A348MWE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciecola sp|TrEMBL
MVSYAQGVDSLNQTLSELREINVSFEFFPPSNDKMENMLWKSVERLAPLKPAYMSVTYGA
NSGERDKTHNVVKRIQHDLGVPAVPHLTCVDASREELIDIAKEYWANGIRRIVALRGDLP
PGMEKPDMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGANEAIT
QFFFDTSHYLRFRDRAAAAGIDLDIVPGILPVTNYHTLVKFAGFTDVHVPNWLHKMYDGL
DDGDQTTRNLLAANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGLRA
>V5V4V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosynechococcus sp. NK55a|TrEMBL
MPSRALAISLSVSRFQAACEQGEFLITAEVCPPKGRDASTMLRQAAHLKGRVHAVNVTDG
SRAVLRMSSWAAAYLLQQQGFEPICQIACRDRNRIALQADLMGIAALGLRNILALTGDPV
KAGDHPQAKPVFDLESVRLLRVIGQLNQGVDSEDRPLADGATHFFAGAAVDPQSASWSGL
QQRFERKLAAGAQFFQTQLITDFGRLAKFMDQIAAGCGRPILAGIFLLKSAKNALFINRA
VPGASIPQHIIDRLAAAPDPLDEGITIAAEQVQQARELCQGVHLMAVRREDLIPEILNRA
GIPPLSASPAPLAKRPHSP
>A0A2E6VTV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MKVSEHLDRAKDTLISYEVIPPPRGKSAQPIIEIVEQLQPYNPPFIDVTSHSAEAYYDEL
ADGSVQRRIRRKRPGTISLCGIIQNRFKIDTVAHVLCRGFTKEETEDALIELNYLGIHNV
LAIRGDETNYKKPMANNRTANVYAEDLVEQIEELKQGQYLEHVTNAAKLDFCVGVGGYPE
KHFEAPNLKTDIHYLKRKIDAGAEYIVTQMFFNNDAYFSFVDACREAGITVPIVPGLKLL
KSVKQLTTIPKNFYVDLPDELVDEVMENPQHVKEIGFNFALKQCEDLLNRGSKYLHFYIM
NDASGVLGIVDKLNK
>A0A0U3E7I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paucibacter sp. KCTC 42545|TrEMBL
MSTPNKTPVSFEFFPPNTPVGTEKLKTVVKDLSVLNPHYFSVTYGAGGSTREKTLATVMD
IAASGYEAAPHLSCVGSTRENIAEILATYRAQNIRRVVALRGDLPSGTATAGEFRYAAEL
VRFIRETQGPDWQIEVAAYPEYHPQQRYAAKDLQHFADKMKAGANAAITQFFFNPDAYFN
FVDEARKLGVDAPIVPGIMPFHNYARIAQFAARDGIEIPRWIALKMEGFMDDAASIRAFG
LDVMSRVCERLIEGGAPGIHFYTLNQSGLTLELCKRLKLG
>A0A2N6C443|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKSGSRLERILKAGHFAVTGELGPPKNGDPEVVRQKARILKGHVDAVNITDCQTAIVRMS
SIAAGLITQQEGVEPVVQMTCRDRNRIGMQSDILGASALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMVKNMRDEKQFQCGEAIKSSEPRLFLGCAANPFAFPFEFRAKRLAKK
VANGADFVQTQIIYNVEKFARFMEMVRELGLHEKVHILAGVTPPKSLGMARYMKNFVPGV
EVPDEVIDRLSAAKDKQDEGINICVDIINQVKEIEGVAGAHVMAIEWEEAVPEIISRAGL
DGRPVLDDDQPEAPAAPAPERIEVTTTAPVESKAADAALAEAKAEAEKIIAAAKAEAAKL
VETQKSVAPVSTPAPTAEKDTIVETQDEAGEHEMNERERLLALESVQNGLKALKQAFNLT
DDQFEALANFAGAKSVLEKDPNVTPAAAAPSAPATPAAPAPETPAPESPAPAAPAAESAA
APATPAEKAPLTPQTAADLPSAVVARYEELMKRAGGTVPSGLTGEAADIAAQDSAKVEKK
AEEATAEKQKKEEKAKEPAAEKKAPAKKKAAPAAPVATGDVAALAAQEVPLAERCTKVPA
DAYTQQYSGAIRETVLGNGDNTITVGGESTMAFQLFEGSMDNKPRIAMDILDVDPSDWPE
GLRKHFEDVIGNPVEWARKCVKEYSADAICISLVSTDPNGMNRAAAEAAQTAADVINNID
VPTIVWGCGNAEKDTDTLREITSLIGDKKVCLAPLEDANYRTLGATAMAFQHPIVAASPI
DVNLAKQLNILLQNLGVTLDNVLIDPSIGALGYGIEYTYSVMERIRQAALTQQDDKLQVP
MICNLGREVWKAKECRLPTDEFLGDQETRSVMMEAITASCMLMAGGELMIMRHPKAVNLT
RALIEGLMA
>A0A329Z8R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. 11-8110|TrEMBL
MNMIETFIKTLRSDEKCFTYEFSSPASFTLEALFETIKKENLPSKINAFVCTDSPLAKLK
HNAILASLKLQNTFKIPSITTMSMRDRNTLALQSELIGMNSLDLRLILALTGDPMRHGNQ
PQAKSIFEGNSNVLLKTICQLNTAKDINNNQIQGDFKPFYPFSVLNSYANKKQNLYKKMQ
EKIQNGALAIFTQPIYDLEIAEELLQWINQINQEYNTHCILMFGFFPITSYKTALFLHNK
LPGVFVPQDYLKSMEKAFQKGIEFEVGLQKSQELFNHLCKIHHKIHLMSANKADIIGKIL
NG
>A0A1D7MDK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus polymyxa|TrEMBL
MKPDLRTVLNREIIVGDGAMGTFLYQLGFPVNTSFEELNITSPDVISDVHGQYLSAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
LELARNYEQQIDALLSEGVDGILCETFYSLDEIRIALHSVRKYSDIPVICQFAVDQVGRT
QDGFLVAEAFSVLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAKSFVDLGTRLLGGCCGTTPEHIAAISKALNRLQPPPLASKEALS
KESFQVAERIADEEERGNGRHTSEPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHALK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYVMTQPVYDHELIAAIAEATRHLEVPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGPEGRAMGVSIAKELLDTAMEHFNGIYFMTP
FMFYEMTAELTSYVWQKSGRAQAPLFRL
>A0A8E2W9W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium loti|TrEMBL
MIGRQRDENPAGIDLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIASGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A7W0EKL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MTTESSFRRSLFDRNQFTLTFELVPSRGGHSKGQSRLLNLARQAAADGRMQAVSITENAG
GHPALSPEVLGQEIQAMGLEVINHFSCKDKNRNQMESLLFSWDRQGLHNLLVLSGDYPQE
GYQGRPKPVFDLDSVQVLDLISQMNRGRIEASHPEAALEFTPTSFLKGVAVSPFKLLPSE
LFLQYAKLHRKIKAGADYIITQLGYDARKFHEVLLYLKLNNFNLPVLGNVFIPNLTVAKL
MHHGEIPGCVVSDTLYAQIMEEAASPDRGRQARLIRAAKLLAILKGLGYAGAHIGGPGLT
FTDLDFVISQAHDLTPDWRDLVPELTYWPDNGAYFYAQDPENGLNMAQAIKDPAVNPGLS
IPYALSHAVHSLFFEPDGAGFTLARKLCLGLGEAGYDTLLMRIEYLIKLLLFGCQNCGDC
RLADLAYLCPQSGCAKYMLNGPCGGSQNGWCEVYPNRKRCFYVRIYRRLARYGLIDIMKE
APTRPRDWSLHNTSSWLNFFNNFEQKP
>J9G0H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gut metagenome|TrEMBL
MKVIDLIHNNEKTAFSFEILPPLKGTGIEKLYETINTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHEAVFTPENDGYNHAIELQKQINQFNRGIFVDGSEMKITNTPFSYGVACYP
EKHEEAPNMESDLYWLKKKAEAGAEYAVTQLFYDNKKYFKFVRLAKEAGINIPIIPGIKP
FNKLSQLSMIPKTFKIDMPEELVKEALKCKNNAEAEQVGIEWCANQCRELMAHGVPSIHF
YSIGAVNSIKEVAKMIY
>A0A2N6C766|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MSSHAAGVRRFRQSLHNTDEFTLSFELVPGRGGRSTVHTRALDMAQAMVADGRICAVSIT
DNPGGHATLAPDVLGQEILAMGLDVISHFSCKDKNRNKMESLLFGWDRLGLHNLLVIAGD
YPQKGFCGHPKPVFDLDTVHLIDLLSHLNKGESDLDVQPTSFHIGVAVSPFKYSEAEQMM
QYYKLQRKIDAGAHFGITQLGFDARKYHEALLYVEEHGLALPLLGNLFIPTLKVARLIKK
GAIPGCRMPEHLFRQMEKEARSQDKGRKARLERAANQLAVLRGMGYSGVHIGGPTLTMAD
LDFVLNQAEARQEQWPELLVEFRPDISAAFYYFQADPATGLNSRQRTALSPAKRQPPLYH
LSNLIHNLAFAADGPLYRPARTCCLALDKTLLRRPLFWLEHLSKFILFSCRNCGDCTLAE
YGYRCPQAGCAKYLLNGPCGGSIDGWCEVYPGRKRCHYVLAYERLKSKGAADAFSRGYIP
PRDWSLEDGSSWVHFYAGLDHSNRCCDRQDTAPSTPKKE
>A0A2S6T510|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha3_Bin6|TrEMBL
MGVSFEFFPPKTPQLEKSLWCSVERLAPLNPVFVSVTYGAGGSTRKKTHKIVTRLQNKMG
IPAAAHLTCVAASKAEVNRVARRYWEAGIRHIVALRGDPPDGQGKYVAHPEGYNNASDLV
RGLKQIGDFEISVAAHPEGHPEAKSIEADIENLKRKVDEGATRGITQFFFQPEHFLRFRE
KTQKAGLSIPIIPGILPVTNFSQVRRFSKVCGASIPHWMSTLFEGLDNDPDTRLRIAANI
AIDLCRILKAEDVTNFHFYTLNRADLTYAICHVLGNSRNT
>A0A2H6JXU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon BMS3Bbin15|TrEMBL
MKHYSELMRSLKSSEFTISGEIDPPKDVNPDEVKEQVKHLKDTVVAANVTDNPIGDVIMN
TLAPCVIMQDLGLEAIYQQTCRDRNRIALQSDIIGAAALGIKNVLALTGDHPKMGNHPQA
KPVFDLDSVQLTGMLRKMREGSTLAGTELENPPEFHIGVGISPGIEPLEPEIIKLEKKVE
AGAEFAQTQVIYDVKILERLKDEAFHLDLPILPGFAPLKSVGMAKFMLKYVPGIRIPEET
MKKLEESKNRVETSIEIVAELIAAARDLNFPGVHIMPVGMDAHVREMVERAGEI
>X6DRJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNHC221B00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKSDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILQETSLTPAAHMTCVDAARHEVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHADGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A4Y7KZR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Papaver somniferum|TrEMBL
MKVIEKIQEAALNDKVVFSFEFFPPKTDDGVENLFERMDRMVSHNPSFCDITWGAGGSTA
DLTLDIANRMQNQICVETMMHLTCTNMPVESIDQALNSIKGNGIQNVLALRGDPPHGQDK
FVAVEGGFACALDLVRHIKKNYGDFFGITVAGYPEAHPEVIGEDGVASPEAYQKDLAYLK
EKVDAGAEVIVTQLFYDTDNFLKFVNDCRQIGIACPIVPGIMPINNYKGFVRMTGFCKTR
IPAEIMAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMDKTALAILQNL
GLIEESKISRTLPWKRPTNVFRVKEDVRPIFWANRPKSYISRTRGWEQYPQGRWGDSCSP
AYGALTDHQFLRPRSKDKKLQEEWAVPLTSVEDINEKFSKLCLGKLKTSPWSELDGLQPE
TKIIGEQLGGINSKGFLTINSQPAVNGVKSDSPAVGWGGPGGYVYQKAYLEFFCSKDRLS
SLVEKCKAFPSLTYIAVNKAGETLSNVSPADVNAVTWGVFPAKEIIQPTVVDPTSFVVWK
DEAFEIWTRGWARMYPEGDSSRTVLESVQSNYFLVSLVDNDYINGDLFGVFRDL
>B0CSW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686)|TrEMBL
MKLSDKIAAHDPSQPFYTFEFFPPRTDQGFENLVSRISRLATLNPLAISVTWGAGGSTKD
RSLELASLTQGDYHLDTLLHLTCTNMEQGLVDEVLKAVRDRGIQNILALRGDPPRGEEEW
IPSDPRFTHAVDLVSYISASPEYSSDFCVGVAAYPDGHTESTTDEDKEIDYLKAKVDAGS
DFIITQLFYDVDQFLRWLAKIRSKGITVPVIPGIMPIQTYASFVRLTKLCGTRVPACITE
DLAPISHDDQLVKDYGVKLAVQMIRRLRLEGGIQGFHFCTLNLEKSVQRVLETLRWAGDT
PGTMEPPAEMGPPDLLITPTSATDTATSTLATISVTDGEAGRGELNNAATWDDFPNGRFG
DFKSPAFGNQDLWGGSGISGSDVLAQWNNPKSLDDLTQIFLGHLHAKILTTPFSPTPLSS
ESLMILPHLERLTRRSWWTVGSQPAVDGVSSGDKVVGWGPRGGYVFQKGFVEFFCEEKDM
DVIERRVERNGHGWVHYFAGNYKADGECRSNVPEGGRNAVTWGVFPGQEIAQTTIIEKES
FLTWKDEAFSIWSEWASFYRPGSEERKLLEGVRNERWLVSIVHHDYKDPQALWTFLFDGN
DS
>N8VEL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 899|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A0L1JRN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudaestuariivita atlantica|TrEMBL
MPLPAVSFEFFPPQTMAGSFRLWDAVQTLAPLDPRFVSVTYGAGGTTRDLTVEAVDALSR
QTDLTVAAHLTCVDATREETLDLAARFAKVGVRDLVALRGDPAKGSGAFEPAPGGFAGSV
ELIAALAETGQFTLRVGAYPDPHPEAASPTADVDHLAAKIDAGAHEALTQFFFEPETFLR
FRDACAARGIAAPITPGILPIEDWSRVKRFAARCGAKVPTWLDEAFATADRDGRSDLLAV
AVCTELCSTLIDEGVETLHFYTLNRPELTRDICCALGLRPRASLQKVA
>A0A3L6S883|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panicum miliaceum|TrEMBL
MKVIEKIQQAAADGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYTNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALAILMNL
GLIEESKVSRPLPWRPPTNVFRVKEDVRPIFWANRPKSYITRTLGWDQYPQGRWGDSRNP
SYGALTDHQFARPRGRGKKLQEEWAVPLKSVEDISERFTNFCEGKLTSSPWSELDGLQPE
TKIIDDQLVKINRKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLELFCAKEKLD
QLVEKIKAFPSLTYIAVNKDGESFSNVPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWTRGWGCLFPEGDSSRELLEKVQKSYYLVSLVDNDYIHGDLFAAFKEI
>A0A653NDY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. AX2bis|TrEMBL
MAELFAEGERSFSFEFYPPKDEAGEEQLWRAISELEPYRPTFVSVTYGAGGSSRDSTVRI
TSRIAHETSMVPIAHLTCVGHTRTELEAILDTYAAAGVHHVLALRGDPQEGPRAPWTATP
GGLDHATELVELARARGDFRIGVAAFPEQHPSSASLDHDADVLVAKARAGAEWAVTQMFF
RAEDYFSLVQRVRDRGCDLPVLPGIMPILNLANIEKQGELIGTTVPADVVDRISAHAGDA
AAMRAEGVAMAAELCRDLLDGGAPGLHFYTLNRSKATLEIFSALDVRV
>A0A1H1L3R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutus sp. GAS368|TrEMBL
MTADRPISELFVQQRPLRSLEFFPPKDDAGVETLRQTALALKRIAPDFVSVTYGAGGSTR
ERTAQVSRLLRTEIGFTVMPHLTCVGHTREELNGVADQLHAGGYRNIMTLRGDPPKGQTE
FVPYQDGLRYGSDLVALLKARHADFCLGVGGYPEKHPEAPSLEIDLDNLKRKVDAGAAFI
TTQLFFDNAVYYRFVEKCRARGIRVPIVPGIMPVLSLKQIKRFTEMCGATLPHKLTKRLE
AAGEAPEIVESVGNEWAVTQIRDLVAHGAPGYHLYIMNRAKAALALAAGLAA
>A0A4T0FKH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia hederae|TrEMBL
MKITEKLQAAEREDRLWWSFEFFPPGMTNLVDRIERMRRLGPEFIDITWHSGGRTAELTT
ELVKTCQASIGVETCMHLTCTGMPREKVINALEEAKRNGCTNVLALRGDPPRGQTEWYPH
PNGFTYAADLVRHIKREYGDYFEVAVAGFPEENPQYRHASNETLEMQYLKEKVDAGADLI
MTQMFYDVGIFIDWCNRVRAAGITVPIVPGIMPIQTWNGFQKAVQMASTKVPESWMEQLE
AVKDDDASVRKVGTKLVSQMCKQILEANIGIRGLHLYTMNLERGPKMILQELNLIPQTQI
LNPLPWRPSLTPTRRTENIRPIFWANRQKSYLSRTEMWDEFPNGRWGDSRSPAYGELDGW
GPTINLKAEDALQIWGEPATYEDICSLFSRFCLNDLKALPWSDQPPARETSVIDRQLAKM
NEIGFFTINSQPAVNGARSDDPVHGWGPKGGYVYQKAYLEFFVSPDNLDKLISRIELNPM
MTYYAVNKRGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGYQWS
DYYKQGSTSHDLIKQIMDTHFLVNVVHNDFKNGQDIFKPFIDELDKAAIDDTIKN
>A0A1V6GJI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium ADurb.Bin063|TrEMBL
MQFIRDIYANGRTAGRPVFSFEFFPPKTDEGDRILFEKTLPALLQARPDYCSVTYGAGGS
TRDKTLRIVERIQRQHALTTVAHLTCVCATREQIGELLAQLRALGIRNLLALRGDPPGGG
EFQPAPGGFEFARQLVQFIRAQGDFSIGVAGFPEGHTACRAGRHADWRHLKEKIDAGADF
VLTQLFFDNADFFCFRDHLTRELGVQVPIVPGVVSILSGAQIQRFTAMCGASIPAPLAAR
LAELGGDDAAVAEFGIEYATRQCEGLLQADVPGIHFYTLNKAAATVRILQNLGRAR
>A0A353NCS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MELKTKSKLEKVFKSGQLAVTSECGPPRSSDPEHIIKKGHIIKNHVDAINITDNQTSVTR
LCSLASCIHLKLEGMEPVLQMVVRDRNRIALQSDILGAASFGINNMLCLSGDHQSFGDHP
KAQNVFDLDSMQLIQTVRHMRDEGKFLGGEEIKVPPNLFVGAAANPFADPFKIRVPRLAK
KIAAGAEFIQTQCVYNLEKFELWMKGVVERGLHEKVFIMPGITPMRSVGMAKYMARAVPG
MDVPEELIKRLSGVPKEKQAAEGITIAVEAIQRLREVKGVAGFHIMAIEWEDKVPEIVER
AGLYPRPKFD
>A6BDT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea longicatena DSM 13814|TrEMBL
MKISDILVEKTPHLSFEVFPPKTDAAYEGVLKATEAIAELKPSYMSVTYGAGGGTSKNTV
KIASHIKDKYNVPSLAHLTCVSSTKEEVHQVIDQLKAAGIENILALRGDIPQESEFPLPN
HYQYAYELIEDIKSQGDFCIGAACYPEGHVESEHKKDDIAHLKQKVDCGVDFLTTQMFFD
NNILYNFLYRAREKGVTVPVIPGIMPVTNANQVKRILSMSGTNLPERFKAIVDRFGDNPK
AMQQAGIAYATDQIIDLFANGINHVHVYSMNKPEVAAAIQANLSEILNK
>A0A285BRJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TLI_55|TrEMBL
MLATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVKETQQ
IVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMADWVPHPQGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDTDVEHFVDKCRAGADYAITQMFFKPD
SYLRLRDRVAAAGCATPVIPEVMPVTSVRMLERLPQLSNASIPSVLKERILTAKDDPAAV
RSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>N9HSW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii NIPH 478|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMYLAEFPCAITLADRVHADSDLAPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKSIQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHKIAGIVITPHMLRVLAQEKQDGRTENA
YKRCAIQILICKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVET
KKELVPQLAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTSAEKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A2M8T5I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. SN1|TrEMBL
MGLLEDLQKQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETSLPIMLNVSMHEQGVLQDGTP
LSEALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTRAKEFIS
VQHERTEPGLNEIAAEKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDSIRETMALAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIK
QKDEQRQNIYLH
>A0A1T4VKX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paradesulfovibrio bizertensis DSM 18034|TrEMBL
KLPRLLNSMRIRKGIIPLRGGLGAGPQPFPSHLCSHKLDKKRSGVESILPTYRMWEREKK
KMEQRLTEELKRRVVLADGAMGSRIFEKGIPAELSYDELNISHPELISEIHAEYLQAGAE
LLETNTFSATSLRLERFGLAGKTHEINRRGAELARAAAGEHCQHRQCWIAGSMGPLGRLE
EMPSAHKIAELYTEQAAALLEGGVDALILETFTRLDMLLPALEAVRKLTELPVIAQLVFT
AQGSSFSGLNIEDSLRRLEDAGADVVGTNCGSGPLGVLRALRNAGTRQCPLSAFPNAGFP
EQIGDRMLFNSDPSYFAQSALQAIPLGARLIGGCCGTGPAHIAALRKALDAGEYRKVKQP
EPQPETGTTGEELRALPETLFSRKLRRGKKMILVELDPPKHLDTGLALEAASALSRAGVD
AITIAENPLAVPRLSNTTLAGMIHRRTGSEVIVHITGRDRNLVGMQATLMGLAAEGLSNV
LAVTGDPPPSGSDDVVKGVFDLRSFDLLDLIRRFNKGMNHHGDSMRLRANFCAGAAFNPN
TKNKPMQVRRMERKIENGAGYFLTQPVYTKADVDAVADMTAHISAPIFLGIMPLISSRNA
EFLHNEFPGITIPDDIRQRMKDAGDKGVDEGIEIAWDLVQHAWDKFAGIYIMPPFNRYAI
ALELMKRLQQNGMWEA
>A0A845G5V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rugamonas sp. FT82W|TrEMBL
MANHNFSIEFFPPKTAEGAEKLRVTRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILA
AGEDAAPHLSCVGGTRESIREILAEFKAHNIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGEWFHIEVAAYPEVHPQAKSPQDDLLAFERKIKAGANAAITQYFYNADAYFQFVE
QTRKLGIDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQAAATTALWQRLV
>A0A7S2RQZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|labyrinthulid quahog parasite QPX|TrEMBL
IVSSTRFFWASLMMTTRWAVEVTPKWVLSQASKGLVHPGLKGKRVNVAFLPTQSENNVVQ
ACRFLKESCLAKPVCHVPARKFVDGHHVSDFIHRLAEVGVRDHFAISGDGQPSGEIKDSV
DLLKIMHDMQDTFDSIGFAAYPDGHASMSDATLDQALIEKAEMFNPGKGFAVTQLCLKTQ
SLVSWDERLFKRTPELDGFPVWVGIFGPVKLEFMRRLSQRLGFSKALDLEIVERERANTD
GKLHGSDDLVREVQLLATTGKLCMDIRGFQVSTFDDVDRSLTWINEV
>A5GP44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. (strain WH7803)|TrEMBL
MSSALQRSLEAGSITITAEVMPPRGGDPAHTIAMAECLRGRVQAINVTDGSRAVMRMCSL
AVCRLLLDHGLEPVLQMAGRDRNRIALQADLLGAHALGIRNVLCLTGDPVRAGDQASVRS
VHELESVRLLQQVSAFNRGEDPVKDRLVDGPTNLFAGTAADPHCASWSGLSRRLARKREA
GARFVQTQMVMDPHALERFCRDLADPLELPVLAGVFLLKSARNARFINRMVPGACIPDHL
IDRLDQAKDPMAEGIAIAAEQVRQFTGIAQGVHLMAVKAEQRIPEVLDRAGVSLPVQ
>A0A4R0XZJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4862|TrEMBL
MTKRVPISFEFFPTKTDVGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFIIEVAAYPEMHPQAESFDKDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVIDLGLA
>A0A8G7RX81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSALTQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A3M8B4Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus gelatini|TrEMBL
MTTSKKDLREYLQDHLLVGDGAMATQLHALGAPVGVSFEELCLSNPRVVHEVHASYYQAG
ARLLETNTFAANRDALSRYGLEHKVARINRLAVAIAREAAQNDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGVDALILETFLDLEELLLAIEVIRPLTEVPIIAQLATLEV
GRTRDGYALTDAFPQLKKAGADIIGLNCRLGPAEILRSFESTIFPDDSLLSAFPNAGRLG
MTDGEYAFKSSPEYFAESALRLRDQGVRLIGGCCGTTPAHVKAMADALAAQKPKARVNPP
VPQGERPHISVQSLREREKPSIVDRVKTGTTIIVEFDPPRDLDAEQFLEGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKNRHGIDPLLHLACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGISFSGRPLKQKAQFIVGAAFNPN
VRNLAAAVARLEKKVEAGADYIMTQPVYDVESIRQVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSAEALERMKRVQGPAARQEGIAIAKELLDEAIRYFNGIYLITPFNYYE
MTVELIAYVRQQSALVKMAQP
>A0A662RDK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon|TrEMBL
MDHIQQRRAFVVETLPPRGPNPERYLSYVRSVWKLGVSAIAVTDMPLARVRVSPWAVSGL
MIREGMEVLPHFSRITRNKCRIESDLLGFHVLGVRNLLLLSGDDPSHGDYPESSKVQDLS
IYDLVRLVKLMNTGTDLAGNKLNAPTEFHVGAVFGHNFDEEVERVEKKIEAGVDFFISQP
VFKEENLQRFLGKLSKVPPILVSAVVFKNRSQLSHFASVPGVVLPKSFVELLEKGRSDEY
IKAYTTDYVLKVVEELQPHVCGVYVAGIVRDLSFMSQLSQMLGSECF
>A0A6J4R902|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Rubrobacteraceae bacterium|TrEMBL
MIGEHGETPKGGREGHATAPLRGLEHPRYELVPVEGAREQAVHLPDGAEVSVTCSPALGI
GATLAFAEDLLGRGFRVVPHLAARLIEGEAHLKEVLRRLEGGGMRDVFVVGGDSKSPAGP
FASGLELLEAMARLGAEVERVGVPAYPEGHPFVPKGELRRVLLAKQAYASYAVAQICFEP
RTILGWLAEAREGGMELPVYAGVPGVVDRRKLLRISLRIGLGDSVRFLKKQSGLAGRLLR
PRGYSPDALIEGLSPYIGDPAYGLRGVHINSFNHVEETEKWRRRMLGMLRHEGVSNGASH
SAPASMRGKE
>A0A7J4NV93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon|TrEMBL
MGFADVLGSGKFVVTAEVSPPKGTDISGALAGAGLLLGLVDAVNVTDNQRSMMHMSPIVL
CHKLGEMGFETIMHMTCRDRNRLALQSDLLAAHALGIHNILAMSGDYPTMGDQPSTKPVF
DLDSVQLLQLIEKMNNGSDFQDKPLDGPTSLYAGAVANPGARPLGPQLLKLNKKVLAKAR
FIQTQAVFDAAVFNEFADAAGHIGIPVIAGIIPLRSVKNARFMIEKIPGVKIPDEAISRM
ETADDPALEGMRIAAETIAEIRTNCQGIHIMPIGGHGNTRRLLEMCGLD
>A0A7K6ZSM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothoprocta pentlandii|TrEMBL
MVNENQHTCSASSSSKSDGGSSSGSESSKESSRCSTPVLDAERHERLREKMRRRQDSGDK
WFSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPAGEEWQEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAENYEADQRHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATIEVLKRLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWSSRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKALKKYETRVNY
HIVNVKGQNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A5N0TCD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium caowuchunii|TrEMBL
MTGKDIPGLEQARATIPAGTKINVTFLGNEDLDMRVAASKAVKDMGFIPVPHISARRLSS
QAQLEEFLGRLQEVGATEHVFAVGGDPAEPEGPYPDSLSVIRSGILQKYGVKEVSIAGYP
EGHPDIPNDVLWRHLEDKSAALKDAGLDAVILTQFAFDTDPVTTWIQGVRDRGIETEIRI
GTPGPAGVKRLIGFARRFGVGANAMIVKKYGFSLTNLMGTAGPDRFVTDLAALLAQNPTS
GDVKLHFYTFGGLLATSQWARDYVAARS
>A0A521SH99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MKRLKEAITSGEFLLTAECLPPKGTDISRFRDHAERLLGKVHAVNVNDNPAAIVHASPLA
LSKVLLDIGHDPVCQITGRDRNRLAIQSDLLGLQILGVRNVLCLTGDDITVGDQKEGKAV
FDLESVEILKTVVGLNEGKDLSGKPIEGATSLLPGAAVSPEAEPLAPALIQSKKKIEAGA
RFFQTQAIFNPDRFDRFMEEARKFSVKIIAGVFLLRSLKTAQYVNEHIPGIRVPERFLQK
LERAGKAGELEAGMEIALELIESIKRKCDGIHLMAVGAEEQISVILERAGLVSSGGVGRR
AVGGAHG
>A0A524B5J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium mtb01|TrEMBL
MARIADLIAAGRTFSFEFFPPKTDMAQLTLGRTIAELESLSPSFVSITYGAAGSTRLRTQ
QLVQWIRQETSINPMAHLTCQGHRRSEIAEILDTYATSDVQNILALGGDAPADGSAEPSD
YTYASDLLDDVLASGRFSVGVAAHPEIHPRSPNRESDRHHLAEKLHRADFAITQFFFEAE
TYIRLVDELAALGVTKPVIPGIMPVTNKSQIVRMAQLSGTAFPTWLAESLNEVDDPDDVR
RVGVDVATDLCARLLEAGAPGLHFYTLNRSTATREIYANLDLPVKG
>A0A2I1UQH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. dentisani|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLQTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1E7GPJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium S5133MH15|TrEMBL
MDAADQNSNSTNSYSLIAEIDPPKGANLAGFLDTALKVRGRVDSVRVTDSEHAIMRMSPI
APCLALLDKTIDPIMIITGRDRNRISFQADLLSAAALGIKKIVIKEGHDPAEGDQPVART
SGDLDLVSMLQCAAALNSGKDLAGESLDGGTDFEIGVSVELSDDVNFNRERAEFFMQLGD
YGVTSVTLGPTYDINIVEQFVPFAEKTGIKLYSSLMFLKSVTMIRYLNNLTGAPSIPQEF
LKKMMQAPVKKDAGMQVAADFMEELSTLGDGIVLLAIGWKGRLPEFLDLIDR
>A0A127HTI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas azotoformans|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKSAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQAHSFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITNMCEDLLNGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>C5L500|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perkinsus marinus (strain ATCC 50983 / TXsc)|TrEMBL
MGVQNLYERLDRMAELGPMWIDVTWGAGGSSSSSNKTFEICRNALTYHGLDVMMHLTCTQ
QSVEEIDEVLDKCKEVGIRNILALRGDAPTQSSEWRACQGGFSHAVDLVRHIRGKYGDYF
CIAVAGYPEGHLEAESIEEDLVHLKEKVDAGADLIITQLFYDTEVFFKFVAAVRKLGIQV
PIFPGIMPIQSYSGFKKMTEFCKTKVPRAIADQLEQVKGDDQRVKDLGVEICVAMCSQIM
SYGVDHTHSSGGLHFYTLNLESSVCRIIERLMMVDNHVATRVLPWRPSKASSRQEENVRP
IFWRNRQKSFIQRTSSWDEFPNGRLGNQASAAYGDFELNFRSYSKETQEKVAADRRRMWG
DHVPNGDHVRRVFTDFIKGEVKRLPWCTEPPTEETLFIQKQLIRLNQCNMLTINSQPRVN
GALSTDPYVGWGPAGGFVYQKAYVEFFCPEGQLEQLIRGIEAEKYDSISYMAVTADGSKV
RSNIPPQGQVNAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWNEWMDVYPEDDHQSR
QVLNFIRQHYFLCTVVDNDFVAGDLFSKLTKICTPIPWETLRIENPSESDGHEVPEPSLA
VIAEVYSPRPKPSDCSPRRDANDGITAFAPL
>A0A0U4FIV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentibacillus amyloliquefaciens|TrEMBL
MDQQSSTALFNQAGASRFELIPAKGIVERATAALPSHATLTITCSPTNGIDATIDKSIAL
APHFAQVIPHIAARMIRSEKHLNTVLDRLAENDVHEIFIVGGDQEKPLGPYQHGLELLQS
LATHENGLHRIGIPAYPEGHPHIDTATLNQDFAAKAPLAHYTVTQMCFDPEQVLAWLRKQ
RASGLQLPCYLGLPGPVKLDKLLRIAPRIGVTDSLRFLRKNLKLSRKLMRGYDPSALVNA
YTPYLNESDYGIAGFHIYTFNELDTLEKAGGE
>A0A5S9QBY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|BD1-7 clade bacterium|TrEMBL
MSHSDKRFSFEFFPPKTEAGHAKLEKTWADLNALNPAFFSCTYGAGGSTRDNTFGVIKQM
REQGISIAPHLSFGGDDEAAMTELLDSYKALGVDRIVALRGDIPSGMGAAKIVYANELVE
FIRNHSGDHFELEVAAYPEIHPESKSYDADIHYFKQKLDAGANAAITQYFFNPDAYFQFI
DACTKAGINKPIYPGIMPITNFTNLARFSAHCGAEIPRWIKYKIENCGDDQEAVIETGKE
IVIRLSEQLLAGGAPGIHFYTMNQVEPSKAIYQAIV
>A0A3M2CSH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MHISEILRRHHPAISFEFFPPKSEAASQELFQSIAALMPLKPAYVSVTYGAGGTTRERTH
DLVVKLQRETNLTIVSHLTCVGSTKDEIHQILEKYAASGIHNIMALRGDPPKGQPHYEPP
AEGFRYAAELVAYIKKHFPYMGIGVAGFPEGHPSTPNRLVEMDHLKRKVDAGADYICTQL
FFDNRDFYDFCERCEIAGITVPIIAGIMPITSRKGMMRMAELALGARFPAKLLKAVQRVD
SDEAVEKVGIHWATEQVIDLIDHKVKGIHFYTLNKSKATLRIYESLGIRNSDSLQHSSPA
G
>A0A450ZSR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. TUN|TrEMBL
MIMNSPGLNTRVFSFEFFPPRTPEGRNKLRTTWQRLSRLNPHFFSVTFGAGGSTQSGTLE
TVLEIQQHAGIDAAPHLSCIGSTRVKIREILEHYLSKDIKRIVALRGDFPPDMVEMGEFR
HANELVEFIRTKAGNRLHIEVAAYPEFHPTAPSASEDLKNFKRKVEAGADSAITQYFYNK
DAYLRFVDSCERIGIHIPIVPGIMPITNYTSLARFSEQCGAEIPRWLDWRLREFGEDMNA
LRTFGVDVTTELCHQLLEAGAPGLHFYVLNRAEPATTIWKNLGLSEIPSSGRSVDQ
>A5FV15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiphilium cryptum (strain JF-5)|TrEMBL
MSHTPPRAVLERWLSGPRVDPLPTPALRAPAPAISFEFFPPKTETLEAQLWACIRRLEPL
APRFVSITYGAGGSTQERTHATVTRLVRETTLVPAAHLTCVGASRGEVDDVARRYWDAGV
RHIVALRGDPPGGTAYAPHPEGYAYAADLVAGLRRVADFEISVAAYPETHTQAPSPQADL
DNLKRKLDAGATRAISQVFFETGHFLDFLDRALAAGITAPIIPGIMPVSNFGQAKRISEM
AGTHVPAWMGEMFDGLDDDAETRKMVAASIAAEQVRTLQANGIDEFHFYTLNRADLTYAI
ARILGVKPAR
>A0A6J0XQN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odocoileus virginianus texanus|TrEMBL
MDRPKPKVFPVGHCCPSLGMRASEAGSRRFSVPPSISRNSAMVNEPRGNGGPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEAESFEADLKHLKEKVAAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGAELTSEESVFQVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKTACLCLCACVPACPWVSVCAPVCSHVLTCRMRPSRC
GLSSGASCMRRSPPPA
>A0A5C7DBM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia nevei|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIATDYWNSGIRHIVALRGD
LPPGAGKPEMYATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A4R1BE15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacter taiwanensis|TrEMBL
MADSLNLRERMAERVLIGDGAVGTLLQERGIRYDHPYARANLTHPDVVRRVHEDYARAGA
EILETNTFAANAVKLAAYDLEDRVREINVAGARLAREAADGALVFGAIGPLGRPLAPVGP
IAREEARAIFREQAGALVEGGVDALVLETFTDLDELRLAFEEAEKPGVPVLIYRTFVEDG
ETLAEGLPARVARELAGWGAVLVGSNCTVGPQRMLGIVEQMSAELGPVAAFPNPGLPQLI
GGVVRYRQDVDHFAAYGREIAAAGARLVGGCCGTTPEHVRALAEALRDFEVQEKRPRGGV
SLREVEERPAAEPRSELWQKIKSGAFAVAVEVDLPRGHDISGVVEVSRSLRQRGADAIDI
SDGARARLRMKPVAVAKIVQEAAGIEVVAHISCRDQNLLGLQAELLSAAALGVKNLLPVT
GDPAQIGDYPEATSVFDTDSIGLVHIISRFNRGEDLSGNPIGEPPGFLIGVAFNPTAEDL
DGEAERLRRKAEAGAHAAWTQPVFEVGALERALEKIEDLKLPIMLGLMPLRSARQAEFLH
HEVPGIEIPARIREKLARLPAEDAPRYGVEAAQSVLLKARPLVQGAYIMPPASMPELAAD
VMEALGERSPSPAPEGQTKEDG
>A0A4U9TIJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus capitis|TrEMBL
MSQFLNQLQNNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDNVERIHRSYIEAGANVIQT
NTYGANFEKLKTFGLEHRVKEIHKAAVQIAKRTAHHDTFILGTVGGFRGVRQDDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELKSIVVATRRKYEIPIIAQLTASNTNYLVDG
TEINDALKQLVACGANVVGLNCHHGPHHMQRSFSHIELPDNAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIHYIKTAVQGLTPIKDKKVVPITKKS
NHKPTKVVKQNLTSKVKNGPTVIVELDTPKHLDTDTFFENVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQQYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>Q0GA67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emericella nidulans|TrEMBL
MHIKEKLAQNEAAGKIGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQERVDAALQAAYKAGCTNILALRGDPPREKEV
WEAADGGFRYAKDLVKYIREKYGNHFCIGVGGYPEGADDNSDVDQLIDHLKEKVDAGSSF
IVTQMFYDTDNFIKWVEKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKTHIPPDWLEAL
EPVKNDDAAVKQVGKRLIADMCRRLIASGIKHLHFYTMNLAQSTQLVLEELELTPTAEAP
IPRPLPWRPSLGLNRREEDVRPIFWRNRNSSYIARTAIWDEFPNGRWTDSRSPAFGELEL
YGVGLKGTNEQNIKLWGEPNSLRDLAEVFVRFLEGNLDRLPWSDSPITPETSAIKDALVE
LNRRGFFTINSQPAVNGVKSSHPVFGWGPKNGFVYQKAYLELLVPPYVIDELIARIEANE
DLTYHAVTKKGELRTNTRDSPNALTWGIFAGREVVQPTIVETVSFLAWKDEAYQLGEDWA
KCHEASSPTRKLLQGIMDSWYLVNIVNNDFHNTYDLFELFKDLNVKDLELEISGGITEDK
AHHNGTANGATNGTTSNGTAAEQPVKN
>A0A1Q6SWN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Subdoligranulum sp. 60_17|TrEMBL
MTITEQFKAKRCVFSIECFPPKQTTQMDKLKDTLRQMQAMDPGFISVTFGAGGSAGGVST
AEVADYIQNELHIPTLAHLICMGNDETRAAEILDQLESVGVRDVLALRGDRSPSRPESPD
FKHASDLTSFIKWKKPEFSVHGACYPEGHPEADSLLHDVENLRIKQAAGAEHLLTQLFFD
NMHFYRFLNLARRAGITLPVSAGVMPIVKRSQIERTVSLSSASLPSEFTRMISRYQDDPA
SLYDAGIDYAVRQLRDLIEGGADGIHLYAMNDAAVAAKVYDGIRDLL
>A0A554KP81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parcubacteria group bacterium Gr01-1014_19|TrEMBL
MTRSINERLASREFLVSVQIDPPKPDQLDDFRRTINVLSDIGVDLVDINSSRRLCHDSLL
LAAYLKARGLEVIPHITTRDSTINGLLSQIATANQLHRVKNFLVITGDSYSPGANLNNSP
GVFESDSVGLIGAAMEKLKLTAGLDITLLAAVNQNNPDMELEKLRLKQKIVAGASMFMSQ
PVFDETQLNELLDFYNYHTSLPLLVGIWPLVDSKTLRAIEDGKVSGVVIPDSVLAESKEL
RKDSEGLRNWGLVKALQLVQKAKDKMADGVYIVAPSRQPLQILDFLKEVLRLR
>A0A2E9QAW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MKKIAEILKEEAGKRPVFSFEFFPPKKPEGEQTLMNTIQRLKSLDPDFVSVTYGAGGSTR
EKTRQWVKDIQDKHGITAMAHYTCVGHGRAEILSNLKDLYSDGIRNIMALRGDPPKGEKN
FTPPEDGFAYGSQLIEFIRSTGMDFSLGGGGYPETHMEAPSAEQDLQNLKKKVDAGAEFI
VTQLFFRNDHYFRYVKQCREIGITVPIVPGIMPITSFTQIEKFTEMAGCEIPNELTEDIK
ACGEDRGRLLEVSLGYSIRQCRDLLKGGAPGIHFYTLNQSQATSTILKAIN
>A0A1F3CD18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWA2_31_9|TrEMBL
MKVCELFKKSKKPLFTFEILPPLKGVNISTIYDAIEPLMEFDPAYINVTYHQQETVYKKR
QDGLLEKKVVSKRPGTVAISAAIKFKYKVEIVPHLICGGFTKEDTEDALIDLHFLGFNNV
LALRGDPPKTERFFRPEEGGHKYAIDMVKQIQQMNKGIYLDSDLQNVTKTDFCVGIAAYP
EKHAESPNKEIDMKYLKEKVDAGADYIVTQMFFDNNKYYDFVNSCRKEGINIPIIPGIKP
ITSLNDIKSIPKIFHIDIPYEFMKTIENCKNNKEAAEAGIEWATYQSKELVKFGVPSIHY
FTIGYSQNIVRIAKEIF
>F2IFX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fluviicola taffensis (strain DSM 16823 / NCIMB 13979 / RW262)|TrEMBL
MKVIDHINAAKDTLFSFEILPPLKGANIQSIYDGIDPLMEFKPKYINVTYHREEFIYKER
EKGLLEKIAIRKRPGTVGICAAIMNKYNIDAVPHLICGGFSREETENALIDLQFLGIDNV
LALRGDSIKTESTFKPDPEGHKHAVDLINQITDMNRGSYLVDDIQLAPTNFCIGAAGYPE
KHFEAMNLSTDLHYLKSKVDAGAEYIVTQMFFNNQKYFDFVDACRAIGITVPIIPGIKPI
TTLNHISFLPKVFHIDLPEELSKDLIKCKSNKDVFEVGVEWGIHQSQELKKAKVPVIHYY
TMSTSESVKTIAEKIF
>A0A157R053|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella ansorpii|TrEMBL
MNDHTTPAFSLEFFPPRDLAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRT
LRNLGCDAAPHLSCVGASRDQLREILQAYRDEGVRRVVALRGDLPSGMGGDAGELRYARD
LVEFIRAETGDWFHIEVAAYPEMHPQSGSVKADLQHFVDKVNAGADAAITQYFFNADSYF
DFVDRAQEKGVTLPIVPGIMPITNHSQLLRFSEMCGAEVPRWIRLRLAEYGDDKASIRAF
GVEVVTRLCETLLEGGAPGLHFYTLNSAEAPLGIWKALGR
>A0A838V6Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium|TrEMBL
IQTLAPLGPRFVSVTYGAGGSTRERTHATVARIERETDLTAAAHLTCVEATREEIDAVAE
EYWAAGIRHIVALRGDPPVAGAKFVSHPDGYENAAALVAGLRKLHPFEISVAAYPECHPD
SAHAEADIDNLKRKMDAGANRAITQFFFSPEAYFRFRDRVAAAGITAEIVPGILPVSNVA
QTRKFAGMCGAEIPDWMGRLFEGLDDHPAARQLVAATVAAELARRLYAGGVRHFHFYTLN
RAELSYAICHLLGVRPKAAAREQAA
>A0A2P5AUJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasponia andersonii|TrEMBL
MEPQKSPISNNIIVAGYPEAHPDAIGPDGIASSEAYESDLAYLKKKMEEILVDAGADLIV
THLFFDTDIFLKFVNDCRRIGITCPIVPGIRPINTYKGFLRMTGIPAEITAALELIKDND
EAVKSYGIHLGTEICKKILANGISTLHLYTFNMEKSALAIQMNLGLIEERKVSRSLSVSH
IVEEAEA
>A0A6A2WCZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium apri|TrEMBL
MHQPMFSIEVFPPKRNAPVGTIYDTLDGLQGLNPDFISVTYGTGKSSDRTATARIANTIR
KEYDIPAVAHLTAQYTTREQVDEALDMFRQAGVSAVLALRGDPVPDREPAGAFEHASDLV
AYIREHDPDMTIFGACYPECHPQASDLDEDIRNLKIKVDAGASHLISQLFYDNADFYHFL
DKARAAGIDVPIEAGIMPVTNAKQIRRMVRMCSSRVPLPLESLLDKWSDDPKTLKQAGVI
YASNQIADLVAHGVDGVHLYSMNKPAITRQIWHNVEDLFSPAHTGTDFA
>A0A8D5FRS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomarina profundi|TrEMBL
MNFQKKLAANEFVVLAEMHTPKGVNISRLVNDGARIKGRVDAVVIPDMDNGIMRMSALAG
AVLLKQQGLETVMHMYCRDRNRMALQGDALAAHVLGNQNIIVADSEEMSQSDHSDAATVE
DITEVQLIEALKTLQQGKDMSGFELDGSPDFTIGCTLPPCADDKALEKALETAQEKIAAG
ATFIVTPAVYSVETGNELVAKAGKLGVPVITTVFLIKSLAIAQYIASSEPGSNISEDLIR
RIRKSSDRELEGIKIAGETIQSLKEQCQGVLIQTLGWEHKIPEILDNAGF
>A0A7Z6KTL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. AQ5-07|TrEMBL
MTFDPVRGRSSEGWATRTPSIVDRIASSTGSRIPFSVEFSPPRDADAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSTEELRAMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPEGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
YDTKYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVSAYDAEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGPEENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTPDTSVGTAQAV
>A0A6A2R728|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium adolescentis|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVDEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREKRPDLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCQSRVPEKLSVLLDKWGGDTALLKEAGITY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A7W6J3S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gellertiella hungarica|TrEMBL
MTNVTLDPATRGRLRFSFEFFPPKSPDAEDQLWTTVSELASWNPDFVSVTYGAGGTTQAP
TLSTVTRLIEETPLRTASHLTCVGATREEVNAVVERFRVSGCRRFVALRGDPPSGVGSAY
RPHPGGYENAADLVAGLKAIDPDFDISVSAYPEKHPESRDQDADIDMLALKAANGADRAL
TQFFFDNDLFCRYLDRVRARGVSIPVVPGIMLIQNITQLKRFAGLCGASVPAWLEARFEG
TENNPALRDATACDLAAQQIAELARRGVQEFHLYTMNKANLVNGTLERLGYRRILPMHLC
AA
>A0A4U6AQ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. LC34|TrEMBL
MIIKRIMHKLLDISASSIIPASIEASPAQVLGPASLAGLFPQGVRVYLTDTGAASQVRLV
DAARHLRDLGYEPVPHLAARRIPSRVEFEEQVKRLAGEAGVSDVLVVGGGVDRPAGPFAS
SMDMLSSGIFDRYGMKQIAIAGHPEGSPDFSEETAVAALRLKRDFAQRSDATMRIVTQFG
FDAARFIAWAEGLVASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESVVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVNRGSWQTGGADRSAS
PDSVAV
>A0A0F4I7R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL S-104|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMADWVAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A1I5G1P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. NFR06|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMETRLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHLTCVDAARDQVDGVVREFADMGVKRFVALRGDPAAGVGT
IYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHETEAA
GSAAA
>A0A2G4F903|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MSRSLLIDALRSPVRPTVSVEFFPPKDAEGGARMLKVAATLKPLGIDFASLTYGAGGTSR
DTTITYGAELVKMGIPLIGHLTCVGHSRTELAGIISQYDKAGFSGILALRGDPPKGQQDF
VAHPEGFAHAQGLVRQIAAEQPDRFAIGVAGFPERHPDAVDDLSDIRFLAGKVAAGADFV
TTQLFLDNEDYFRFVARARAAGVVVPILPGIMPVLSLKQARNFCGFCKARIPDALVRELE
ACGPDEEAQRKVGVSWAVRQARGLVARGAPGYHVYILNKAESAVELFAALRD
>A0A2D8FF31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium|TrEMBL
MSPTMDQMREAQRALEAPLFSGLPGDIDVSFEFFPPKNAAMNETLWQSVETLAPLGPRFA
SVTYGAGGSTRERTHQQVVRIQNEARIPAAAHLTCVEATREEVDEVARHYWDEGIRHIVA
LRGDAPDGQSQYAPHPGGYANAVELIAGLKRVADFEISVAAYPEVHPDSPDRQADLDNLK
AKFDAGATRAITQFFFDPQCFFDFRDRAAAAGIDGEIVPGIMPVLSFAAVRRMSGLCGTA
IPPWMXGLFDGLDDRPAARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRAKAGR
>A0A2G4G4L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MPKAEFINRLRAKHRPTVSVEFFPPKTSSDGAAMLETAKILKPLGVDFASITYGAGGSDR
STVLEYGSQLVKAGYPLIAHLTCVGHSREELKEIISKYDAAGFAGILALRGDPPKGQNEF
TAHPKGFAYASGLVELIKESFPNRFALGVAGFPERHPSSPDDLSDIRYLAGKVSAGADFI
TTQLFLDNEDYFNFVNRARAAGVAVPILPGIMPVLSLKQARRFCGFCKAKIPDLLVKELE
SCGEDEEAQRQVGVSWAVRQIKGLLSRGAPGYHVYILNRAQSAVELFKQLEAK
>A2CD52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus (strain MIT 9303)|TrEMBL
MSSALQRSIEAGAVTITAEVMPPRGADPVHSLTMAQGLKGFVHAINVTDGSRAVMRMSSL
ALCRLLLDEGLEPILQLACRDRNRIALQSDLLGAHALGIRNLLCLTGDPVRVGDQPEARP
VHDYESVKLLHQVAAFNRAEDPVSGLLPDGATALFAGAAADPNCQSLSGLRRRLERKKEA
GARFLQTQMVMKPAVLEHFCNEVANPLGLPVLAGVFLLKSARNASFINRVVPGACIPESL
VVRLEQASDPMAEGIAIAAEQVSSYLSLTQGVHLMAVKAEERIPEILDQAGIKKLMDP
>A0A7X1FCA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MSSRFD41|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLADYNPDFFSCTYGAGGSTRDRTVNTVLQLE
NEVKVPSAPHLSCVGDSKDDLRGLLRQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VNFIREETGSHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVQKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSTSIQAFG
TQVISQMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A8I1JAB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ACIN00229|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFERFLEQAQAANIHNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLMKHAYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFSPEISHFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALVAK
VLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKALEQTEILKEKLIPTVAIETRGTSSWKNWYLATEA
>A0A1G8A7L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium congolense|TrEMBL
MKIKNIFEEKEVVFSLEVFPPRPDVPIENIYQTLEELKDIDPDYISVTYGAGGGLRKNRT
CELSSIIKEKYDVEALAHLTCINSDQETLNKILARLESKNIENILALRGDKPVDGEALGD
YNYAYQLVEHINKHNDFGVAAACYPEGHLETESLDQDLEYLKQKVDHGVDYLISQMFFDN
SLFYKFRNKAEKKGINVPIEAGIMPVINKKQVGRIIELSDAYFPKKFQKILDKYEDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKVD
>A0A7T7CCS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salicibibacter cibarius|TrEMBL
MMNRQSSVELFEQMSEPRFEVIPTHNIVERATEALPSHAMLSITCSPTKGVDTTVETAIA
LAPRFARVVPHIAARMIRSEEHLDAVIDVLHAHDVDEIFVVGGDQDQALGPYRHGLDLLQ
SLATREHGIRRIGIPAYPEGNPNIDNDTLAKDLLAKAPFAHYAVTQMCFDPDKVLAWLRR
QREAGLELPFYLGIPGPVKPDKLVRIATRIGVTDSLRFLRKNLKLTGKLLRGYDASGLMN
AYTPHLNDPDYGIAGFHMYSFNELNSLKKIFGRIAI
>A0A7V8N6D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. BIGb0393|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRGIARDYWDSGIRHIVALRGD
LPPGSGKPDMYGSDLVELLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMSAMFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAIGG
>A9A1I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilus maritimus (strain SCM1)|TrEMBL
MTIRYEANPPKILPDVDTDQSIKKFIERIKDISKKCDAIHLTENVLGFQRVSPLEVGKII
KKEIPDLPITVSLRVRDKSEEEISEFVENCINIGFSGILVLMGDPSQTGKTDSGQIPSLT
VKKLKEKNVDSKIDLYLSVSNKPNFSKLGKKKDAKPKGFMTQVVQNVEQVQTLADNLKEF
SVIPIILFPSQKNEKSAEFLDLDLESYSQEFEELLKKAHEITGDVLLTSPNDFTGLNEFL
SKTSF
>A0A1H2NYJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mucidolens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYHPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFENDLQNFVRKVNAGADSAITQYFFNADSYFY
FVERVQAMGVSIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCETLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1W6BMB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus lutrae|TrEMBL
MSRLLEALQHKILVADGAMGTILYSEGLDTCPEAYNLTHPEKVEQIHRSYIQAGADVIQT
NTYGANFEKLQAFGLEHQVKAIHQAAVAIAKRAAHAETFILGTVGGFRSMKQGELSLSAI
QYHTDIQVDTLVAAGVDGLLFETYYDDQELLNAIVQTRQKYDIPIIAQLTASNTHYLTNG
KSINDALQQLIKAGANIVGLNCHHGPHHMKQTFSHIALPDHAYLSCYPNASLLDIDHQSF
KYSDNAQYFGDTAQQLIQEGVRLIGGCCGTTPEHIHKIKTAVKHLQPIREKKVIPIHQKQ
TSETPKSQRQNLAARVRERPTIIVELDTPKHLDTTRFFNNVKALDEAKIDAITLADNSLA
TVRISNIAAASLIKQQFSIEPLVHITCRDRNLIGLQSHLLGLSLLGIHEILAITGDPSKI
GHLPGATNVYDVNSKGLTELALKFNKGVNTDGDTLKIATQFNIAGGFDPHVRNINAAVRK
MESKIKSGMHYFITQPVFTKEKIVEIYEATQHLDVPIFIGIMPITSYKNALFLHHEVPGI
KMSDDVLAQYEAVADDKQATYALSLSICKSLIDTVHQYFNGLYLITPFERIDYSLELAAY
SKSITTSHQEAIL
>A0A7H8SBI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentibacillus sp. CBA3610|TrEMBL
MTMMDQQSAAALFNQTGGPRFELIPANGIVERAIAALPSHATLTITCSPTNGIDATIDTS
IALAPRFAQVIPHIAARMIRSEEHLITMLDRLAEHNVHEIFIVGGDQEKPLGPYHHGLEL
LQSLATHENGLHRIGIPAYPEGHPHIDTDTLNQDFAAKAPYAHYAVTQMCFDPGQVLAWL
QEKRASGLQLPCYLGIPGPVKLDKLLRIAPRIGVTDSLRFLKKNLKLSRKLMRGYDPGAL
VNAYTPYLSESDFCIEGFHVYTFNELDTLKKEVGGV
>A0A1H3FQP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcaceae bacterium YAD3003|TrEMBL
MKINEILKEQTPSISFEVFPPKKEADLDNVKAAAGSIAALKPSFMSVTYGAAGSTSKLTI
EVASDIKNLHGVSVLPHLTCVASTKEHVDDMIKRIRENNIDNIMALRGDIPKDGVICHDF
EHASDLIRHIKSIAPDLCIGGACYPEGHVECARKSDDIHFLKEKVDAGCDFLTTQMFFDN
NIFYNFLYRVKDIGINVPVLPGIMPVTTAKQLSRSVQLSGTAVPERFKAIVDRFGDDPVA
MRQAGIVYATEQIIDLIANGVNHIHVYSMNKPDVAADILNNLKGIVS
>A0A1G8MRV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium congolense|TrEMBL
MKIKNIFEEKEVVFSLEVFPPRPDVPIENIYQTLEELKDIDPDYISVTYGAGGGVRKNRT
CELSSIIKEKYDVEALAHLTCINSDQETLNKILARLESKSIENILALRGDKQVDGEAIGD
YNYAYQLVEHINKNNDFGVAAACYPEGHLETDSLEQDLEYLKQKVDFGVDYLISQMFFDN
SLFYKFRNKAEKKGINVPIEAGIMPVINKKQVGRIIELSDAYFPEKFQKILDKYEDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKAD
>A0A3N7BZB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paucibacter sp. KBW04|TrEMBL
MSIANKKTPPVSFEFFPPNTPVGTEKLKTVVQDLSVLNPHYFSVTYGAGGSTREKTLATV
MDIAASGYEAAPHLSCVGSTRENIAEILATYRAQNIRRVVALRGDLPSGTATAGEFRYAS
ELVRFIRETQGPDWQIEVAAYPEYHPQQRYAAKDLQHFADKMKAGANAAITQFFFNPDAY
FNFVDEVRKLGVDAPIVPGIMPFHNYARIAQFAARDGIEIPRWVALKMEGYMDDAASIRA
FGLDVMTRVCERLIAGGAPGIHFYTLNQSGLTLELCKRLNLG
>A0A653NZW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. 9AX|TrEMBL
MFPIRIEIIPAQGIVEQVQALVPKTTTLSVTCLPHHGIERTMRTAVELSDAGYTVVPHLA
ARSIRSRAELTEIVRGCDAAGIREVFVIGGDRKQQVGAYGSALPVLEDIAQYTGGTMRAG
VAGYPEGHPSISPVDLLDGLLAKQHLASHVVTQMCFAAEKIQDFAALLRREGVHLPVWAG
VAGSVPRTKLVALGAQIGVGSSLKFLSRKGPLARKLLSGDRYSPDSLITGLENRPGSIAG
IHLYSFNSLDSVPTGPDQATTSALQKALTQGAARDN
>A0A2T4AVM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma harzianum CBS 226.95|TrEMBL
MHIKSLVAETEKSKAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLEKVNDALQKAYKAGCTNILALRGDPPRDQES
WTAADGNFQYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGAGF
IVTQMFYDADNFIRWVGKVRERGITIPILPGIMPIATYASFLRRAKHMQCRVPPDWMAKL
EPVKNDDVAVREIGKTLVAELCKKLLANGIHHLHFYTMNLAQATRMVLDELNWTPSAENP
LKQALPWKQSKGFGRRDEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPASIQDIANTFVQYLEKKLETLPWSESGLAAEADPIKDDLVA
LNKRGLLTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLMPPYLLEEMISRLDDFP
NLTYYAVTKNGQLKSNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGVDW
AHCFDANTPSRALIEGIMNEWYLVNIVNNDFRENSTIFGFLEGLEVKDLAVPVTPTA
>A0A3Q9WQ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. MN05-02|TrEMBL
MTDLPVRVEVIPSEGIAERLRGHLPVPAAVTVTCLPHHGPREAVELAVDLARAGYTAIPH
LAARSVTGRAELGRYVERCADAGITDVFVIGGDATVAAGPYAWSGALMEDIADLSGGGLR
MGIAVYPEGHPGTTDEELVRTMLAKQRFASWCVTQLCFSQETLRGYPSRLLLQGVSLPVW
AGVPGPVRMARLVRLAGRVGVGQSLGFLKRSAGAADSGSAVRQLLSSASYDPAPLVGAVH
ASGYAGLHLYSFNDLAGLARSGLAAAAG
>A0A1I6KQC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] populeti|TrEMBL
MKLQDYLKKHRLVADGAMGTYYSRLHEEDKAVAEFGNIKEPKTIEMIHRQYIESGARLIR
TNTFAANTVVLGLKVQEQIEIISKACEIAKTAAGNRFAGISPIGDQREEDLVFIAGDIGP
IPVVMELGEDKVLEEYKRICDLFIEEKLSAIIFETFVDLAYLKELAVYIKQKSDLFVICD
FCVNKNGYTEMGISGSKIWQTVSEIEEIDAIGLNCGIGSGHMHQVLSRMNFPNNKYIVAM
PNAGYPEQLQNRMTFMDNAEYFVDNMAQIAELGIDIVGGCCGTTPHYIEKLAKCISLDPS
VRGNSADIVVSEPAGVQKEIIKNDFYEKLRSGKKVVAVELDPPFDASYEKLMEHAQTLKD
KKVDIITMADSPMGRSRVDSILMSTKLKHDIGVSVMPHICCRDKNMIAMRSAILGAYIND
IRNFLLVTGDPVPSVSRMNTTGVFDYNSINLMSFVKEMNEEHFSREPIYYGGALNYARGV
LEKVADRMKRKMDVGCTYFLTQPIYIKEDIERIYQLKKTTDSKILCGIMPPVSYRNANFL
KNELAGIHVTEEIVARYHMDMTKEEAEQTGADIANEIIGEIKSFADGYYFMLPFNRVSFM
DRITIE
>A0A2H5VUC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR09|TrEMBL
MSWQANRVWRRFEDHVVVADGAMGSELLTRLAPGAHLDLAPLEHPREVLEIHLAYLKAGA
ELLETATFAASRPRLERLQAGDLTEEVNAAGVKLAREAREIAGVDCLVAGSVGPLAGVVD
LDAPEGPAAIAAAHQEQAAILAGRGADLLILETFFRVDELELAVSAVREVTHLPVVAMLT
FPGETHGEDWDGAAEQLRRLAQLDVLAVGVNCAPGPGGTLEILERLGTVSKMLAAMPNAG
LLLRRDGRLLLPPATPSYLAAFARRAVALGAGLVGGCCGTGPDHIRAIVEAVRGARPSPR
QTTVVAVPEPVPSAAPEPKPSPSSFAAKLAAGQFVRIVQLDPPKGTNAQRVLEAARGFAA
HPAIDAVDINSNPLARLRMDSLWLAAEIQRTTGLETIPHITPRDASLMGLQAQLLGAWRA
GIRNLFAITGDPSQLGDYPGVHDVYHVDIFELVRAVARMAEGVDCAGNPIGEPPAFCIGV
AVNPNAEDLAREADRLRRKVEAGAQFAMTQVLFDWALFEKLLDQFQGKLPVPVLVGIWPL
PSLKLALRLHHEVPGIMVPEELLFQLEAAGSGAAEVGAKRARAMLEAAPSYAAGVYLVAP
FRQPGDIVSLLGVAG
>A0A377H1J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Flavobacterium] thermophilum|TrEMBL
MGLLDELKQRILIADGAMGTLLYSHGVDRCFEELNLSNPDEIIHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGGAYVLGTIGGLRTLNKSVVPLDEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALSRLEALGADVVGLNCRLGPHYMIQSLEEVPLPNRAFLSAYPNASLPDYRDGRLV
YETNAEYFEEAAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTRRSVIVELDPPKQLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIVKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDVSSFDLIRLISQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPVYSEEKIVQIYEATKHLATPIYIGIMPLVSARNAEFLHHEVPGIT
LSDEIRARMAACGGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A8I0DW79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. M12|TrEMBL
MTLREKHQQGQFTITVELDPPKSSSAEKTFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDAPTNFYIGATGNPGAPDLEIERQKLAAKIQNGA
HFVQTQPIYDLEQAKHYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
MEKGGKEAGTEIAIETLEQIKKMAAGVHIMPLNDIDTTLYIIDHV
>A0A7M1P6Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parainfluenzae|TrEMBL
MSYANEINTLNQHLADTNKKINVSFEFFPPKNEKMESMLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGIEAAPHLTGIDATPEELKEIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIEAEIVPGILPVTNFKQLQKMASFTNVKIPAWLAKAYEGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHTLGIRPTTNP
>A0A1S8CEE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia oryzae|TrEMBL
MSFFHANQREALNQSLAELSGQINVSFEFFPPRTSEMENTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLDAAPHLTCIDASPAQLRDIAADYWNSGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPSWMTSMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAIA
>A0A2N2RTP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-4|TrEMBL
MTTEISIEFFPPQTPEGVDKLRTVRAELAKLNPAFFSVTFGAGGSTRERTFSVVKEIAAE
GYDAAPHLSCIGSTRDNIREILNEYKAAGIKRTVALRGDLPSGMAETGEFRYANELVEFI
RAETGDWFSIEVAAYPEWHPQARSPKDDLDAFARKVKAGANSAITQYFYNADAYFHFVDE
ARALGVDVPIVPGIMPIVGFTKLARFSDACGAELPRWMRKKFESYGDDSDSIRAFGLDVV
TELCERLLKGGAPGLHFYAMNQSALTTEICRRLG
>A0A0F6Z680|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Brevibacterium] flavum|TrEMBL
MSLTNIPASSQWAISDVLKRPSPGRVPFSVEFMPPRDDAAEERLYRAAEVFHDLGASFVS
VTYGAGGSTRERTSRIARRLAKQPLTTLVHLTLVNHTREEMKAILREYLELGLTNLLALR
GDPPGDPLGDWVSTDGGLNYASELIDLIKSTPEFREFDLGIASFPEGHFRAKTLEEDTKY
TLAKLRGGAEYSITQMFFDVEDYLRLRDRLVAADPIHGAKPIIPGIMPITSLRSVRRQVE
LSGAQLPSQLEESLVRAANGNEEANKDEIRKVGIEYSTNMAERLIAEGAEDLHFMTLNFT
RATQEVLYNLGMAPAWGAEHGQDAVR
>A0A2A3XKI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glutamicibacter sp. BW78|TrEMBL
MPSPTDSPHPLGAELVRGFSLEMTGKDQRSLAEAAGTIPAGTRVNVTFLGNEDAGLRVAA
AAAVRAAGHEPVPHISARRLASFGELDGFLDQLVTQARVTEVFAVGGDPVEPLGPFPDAL
ALIASGRLQAHGVTGVAIAGYPEGHPEIDDASLWAALQDKASAVRSAGLSGSIITQFGFD
TRPVLSWLAELRGRGIDLPVRIGVPGPAGIKRLLSYARRFGISSSAGIAQQYGFSLANLL
GTAGPDRFVNDLAAGLDHRLHGEVRLHFYTFGGLSATARWAQDFRAGP
>A0A2P4WG75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis remanei|TrEMBL
MTNAGGTHVAETQETIKKIDSLSTMPYCGIDTDDNTGVEERATLETGKSWSPKHYELLHE
RIERLIDEKQPFFSLEFFPPRFVNGVPNFLERVERLSEGGSVFVDMTWHMGSDPANIDKV
TSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPGTEL
QDTHQFRALDMIRWIREEYGSYFSIGCAGYPLGHPQAPSYKADLMYLKAKCDAGANFVIT
QLFFEPETFEKFVRDCREIGITQPIIPGIMPIMGYESIKRIATLSQLEIPQHILDDLEPI
KHDDDAVQKYGTERCIAMCRRLLDNGSAPSIHLYTMNREGSIREILKALGLWKLEGDRVF
PWKNRSQHPIRCLESVRPIYWSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLS
NLTTLRNGDDRLSMFGDNIDSIEDVKRVFINYITQTPNAAGKKVTVLPWTEAETGVQPET
SLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSEK
LIQIIQRDFPIRVNYHAIDKDSTFDQTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRA
WRDEAYQMWMAQWGDFYPKESKSYGVIKSIHDTFRLVTLVDNDFQKPSVLFDVLQTALEE
LRKV
>A0A522KW52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp|TrEMBL
MPSISFEFFPPKTDEQRAQLDRVAAALQPAAPEYVSVTFGAGGSTLSYTSDTVRGLHQQH
GFHVAPHLSCMGGSRAEIAALLDEYRAAGYRRIVALRGDLPSGMATAGDFRYAAELVRFI
REHSGDHFHVEVAAYPETHPQAEDALVDLRHFKAKIDAGANGAITQYFFNPDAYFRFVDD
AQRLGVKVPIVPGIMPITNYSQLKRFSDACGAEIPRWIAKRMQAHGDDAASIRALGAEVV
AQMCLRLLDGGAPGLHFYTLNRARATLAVLERLH
>A0A1V3K7V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter pneumotropicus|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMENILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDATPQELKKIAQDYWDSGIRRIVALRGDEP
KGYDKKPFYASDLVTLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHIIT
QFFFDIDSYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPNWLAKAYDGL
DEDPTTRNLVAASVAMDMVKILSSEGVNDFHFYTLNRSELTYAICHMLGVRPSV
>A0A5B7RA69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. S-1144|TrEMBL
MATGRGRSIGELLRDGERSISFEFFPPRDEAGTERLWRAIQALEPYRPTFVSVTYGAGGA
TRDTTVEITGRIARETSLTPVAHLTCVGHTRDELESILDTYAEAGVHHLMALRGDPPDGP
RADWTPTEGGLDYARDLVELARSRGDFRVGVAAFPEGHPNAASRDADADVLVAKAEAGAE
FAVTQMFFRAQDYFDLVDRVRARGVDIPILPGIMPILNVAAIRRQGELIGAEVPADLVAR
IAAHDDPAAVRAEGIAIAAELCDELLAGGAPGLHFYTLNFSRATLEIFERLQITV
>A0A1W1V0A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfonispora thiosulfatigenes DSM 11270|TrEMBL
MNGLKNKLNNKQFVTTVEIDPPKGASPWIVYEKMKNLKGVVDAVNIADCPMGKMRMSPIA
LAHLVQKELQLEAIFHLTCRDRNVIGLQSELLGAYALGVKNILTLTGDKPENGDHPEAKG
VFELDSTGLIKLANTLNQGTDMMGNNLNEATEFFIGGVANPTATDLEIEVSKVEAKIDSG
VNFFQTQPIFDINSLEHFLTKINDTSAHFIYGLMPLKSVKLAQYLNKNVPGIVVPDKIID
RLQLKGREAGLEIAKELYLELKKMVPGVHIFPMGDVPLIEELLQEQGNGKG
>R7XVN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. CF8|TrEMBL
MRELIESGEKSFSFEFFPPKDEAGEERLWRAITELEPYRPTFVSVTYGAGGSSRDTTVRI
TGRIARETSLTPVAHLTCVGHSRAELAEILDAYREAGVAHILALRGDPPGGPHTEWVSAE
DGLEYASDLVSFIKEHYDAAVGVAAFPEGHVSAESLEQDALVLKAKQDAGAEFAVTEMVL
RASDYFALVERARALGVDMPIIPGIMPILNLNSMSRMVELSGREMPDEVRARIEPLAETP
EELRAEGIRISTELCEALLHGGAPGLHFYTLNFSKATREIFAALQITV
>A0A0M7CR22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A0G3G7F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas chlororaphis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASHKPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGDHFHIEIAAYPEMHPQARNFEDDLRNFVRKAHAGANSAITQYFFNADSYFY
FVERVRQLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EDVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A7V9V897|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSGENFEIICEVEPPTRPDLMHVRHQIGVMSKVASAFLIPDNHIGRATVSSVAVAHEVER
MGSRSIACLNARDRNLLGFRRDLLTAAAYGVDQFLFVYGDEPASGSRTGQLTVRSMLDEV
RDFSATPAFGGHAFRAGVTSRLGPLPGWKAEADFVFTQVSFSLEDLLRWRDSVNFDGPIY
AGVMVLASAPMARKLAAEIAAITIPADLVEALVGDRAAGVEQACDLALAIRNSGAFSGVH
LIPVSRYREVAARLEAEVRTLLP
>A0A7W0NM92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPSGAEPSDAGSFLDRSDFGVLCEIEPPRRPSLDHVRTQIEALKPVTDAFLIPDNHLGRA
TVSSIAVAREVAASGCASVACVNARDRNLLGFRRDLLTAAAYGVDHFLFVYGDAPKEGRR
AEDLTVRGMMEEVRTFGTGSLFSGFPNFRIGTAARWDRPLSWRARADFLVTQITFEIEPL
LRWRESLSYDGQVYAGVLVLASSRMAARVNATVAGITVAQNVVDKLDGNPELGVDLALSQ
VEAIRGSGAFEGVHLVPVGRYREVAERLGAARPPSGPGAAA
>A0A7V1U6W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTSRLERLVRAGTFVVTAEVVPPRSADGGAVRAQARELVGYADAVNVTDNPRASAHMSPV
AGAAFVAAAGLEPTMQITCRDRNRLGLAADLLGGWALGARNLFCLTGDPLAVGDEPGAAA
VHDLAVEDLVRMAAELRERGRLPSGAEIDPAPRYFIGVADVPLAPGYDPARLERKLDAGA
GFVMTQIAYDLEALRVWLELARARGITERAALVVGVAPLASAKQARFLHEKVPGVSVPAE
LLAELEDAGERAPEVGVARCVELVRALRDTPGVAGVHVMGLGREAAVRAVIEGAGLLPRP
PAPG
>A0A7K1CJ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MEMRMTGIGESVTYSFEFFPPKDQEGEDRLWSAISALEPIAPDFISVTYGAGGSTRDRTI
RITSEITEHTKLPVVAHLTCVGSTREELIEILARYKSAGIHNILALRGDPTGGPRAPWTP
TPGGLNHADELVTLAAEVGGFTIGVAAFPDGHPASGLNLDQDIEVLLRKEKAGAAFATTQ
FFFEADKWKALVDRLAKRGSNLPIIAGILPVTNVNQLNRMAELSGVPIPAPMRDRFTALK
DSPEDVRKLGVEIATELCEDLLTAGVPGLHFYTMNTSSATREIFAQIKDKKRS
>A0A7K0U6J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
DGPEAVHRVGVEEATRLCRELLDGGAPGLHFFTLNRSMATREIYEALGL
>A0A7K1ASC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVVRTSYSFEFFPPKDVEGEERLWAAIDGLKSITPDFVSVTYGAGGSTRDRSIRIAQEIT
KRTGISTVAHLTCVGSTRDELIAILHSYKEAGITSILALRGDPTGGPSAPWTPTPGGLNH
ADELVQLADEFGGFTIGVAAFPDGHPASYGDFEKDIDVLIRKEELGATFATTQFFFEADR
YTRLVDRLAERGSKLVIIPGILPVTNVKLLHRMAELGGTPIPSQIAEAFAKVESDPVAVR
ALGVEIATSLCQQLLSAGASGLHFYTMNSSTATQEIYGNLNA
>A0A7W1QBG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKVIEHLANATNPFVSVEIIPPRRGANVQRIYEAVSSLMPYAPPFIDITSHAAETVWDEV
PGGTFRRRVTRKAPGTFGLCAAIKYRFDVDPVPHVLCNGFTREETEDSLIELNYLGIENV
LAIRGDGERRVPPDGRSANEGALDLVGQVAAMNRGEYLEDLVESTPTDFCIGVAAYPEKH
EEAPNLERDIGVLLQKQRAGAEYAVTQLFYDNEVFFRFVKSCRDQGVTIPIVPGLKILTR
RTHVTSIPRTFNVAVPEALVAEVASVGDDDVAGVGIRWAHEQTLQLFEQGVPSVHFYVMQ
DTGPLVSLMEMLKQSI
>A0A7K0TPR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSPTRTAPSLGAVLAGGGHSFSFELFPPKTDAGEQALWQTVRELEALKPTFVSVTYGAGG
STQDRTVRITKQIAEHTTLLPVAHLTCVDASVDDLRKVIAQYSDAGVNTIMALRGDPTAG
PESQWVQHPGGLRHADELVALVRELGAFSVGVAAFPEGHPESGDFEDDARVLAAKQDAGA
EFAITQFFFRAEDYERLVTRAAAHGCTMPIVPGLMPVTNVAQIERFAVLSGAQFPSDLAD
KFGKIKDNQSAVHELGVEVAADLGAKLLAMGAPGLHFYTLNRSTSTREVYEALGLNQV
>A0A7W0Q1I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAAPNRFVERLENGPPIVGDGGMGALVTSVVPRLRTPEEANLRAPDAVVSLHVGFIRAGA
ELIETNTFGANRRKLAGHYLEDEFEQIISAGVRLAREAREVTGSNVFIGGSIGPLGDVDD
YHPEERSGLFSEQASILEGRGADLFMLETFFDLEELVVAVEAVRAVSSLPIVALLTFENE
AETLAGVTARAAADKLRELGVSALGANHGAGLQAALRAIEQMGGDGIPLAALPNIGLASM
AGGRVIYPHASPEYFAEFAAHARRLGAKIIGGCCGTTPAEIAAIRRSIDEAREPRAPLVF
RERETAIPVQEAPPETALARMLRKGEWVVSVQLDPPLGGSNAGMLEVAQALKDTGAAQFV
DINDNPRARARMSGIMSAVAIERTVGLETIPHQTPRDTTISGLESLLLGAHAEGVRNVLA
VTGDPPEEGDYPGAGGVYHVEAIGLVQIIERLNRGEDFHGRAIDAPTHFFTGVAVNPTAD
DLELELQRFEQKLEAGAKFAMTQILFDLSYLEAFFERFGEPSPIPLLVGIWPLRSHQLAQ
RLHNEVPGIVVPDHVQQALLDAGPNAPDVGTKLAHELVARSRELAAGIYVVAPFRQPLGV
LDFLR
>A0A6L6E543|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSNDLRDTSFSLEFFPPKDLAGEERLWQVLAQLQPLHPDFVSVTYGAGGSTRDRTIRVTT
EITARTAIPTVAHLTCVGSTKFELIEILNQYKNSGITSILALRGDPQGGPTAAWQSIADG
LDHADQLVEMAMKLGGLEVGVAAFPDGHPASNFDLEKDIEVLLRKEELGATFATTQFFFE
FEKWQKIVDRLSQKGSKLPVIAGILPITNLKQLSRMVELSGIQIPAQILAQFDNAADNPQ
EVKKIGIEIASELGAKLLAANVPGLHFYTMNTAESTIEIAKNLGLVKL
>A0A7N0VE14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kalanchoe fedtschenkoi|TrEMBL
MKIIDKIKAAEEQGKVSFSFEFFPPRTEDGVENLFDKMERMVAFNPTFCDITWGAGGTTA
DLTLDIANRMQNMMAVETMMHLTCTNMPVEKIDHALATIKANGIQNVLALRGDPPKGQER
FVQIEGGLGCALDLVQYIRSKYGDYFGIAVAGYPEAHPDVIQPETGLATPEGYQGDLEYL
KKKIDAGGELIVTQLFYDVDTFFKFLDDCHRIGITCPIVPGIMPINNYNGFKRMTGFCKT
KIPAELSAALEPIKDNEEAVRAFGIHLATEMCKKILAHGVKTLHLYTLNMDKSAVAILMN
LGLIEESKISRSLPWRRPANVFRTKEDVRPVFWANRPKSYVSRTLGWDEFPHGRWGDSRS
PSYGALSDYQFMRPRVRSKKLQAEWAVPLKSIEDIQERFSKLCLGELKSSPWSELEGLQP
ETKIIDEQLGNINLKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCTEEKL
NALVEKSKGYPSLTYMAVNKSGVWISNVGTTAVNALTWGVFPAKEIIQPTVADPASFLVW
KDEAFEIWSRGWAQLYPDEEVSSKNLLQEVQGSYFLVSLVDNDYIQGDLFGIFKEL
>A0A1Q7QW53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon 13_1_40CM_2_52_13|TrEMBL
MQGRVDAITIPALRNREDDPSYPAGFRVTPQTRSLASAVIVRKTGAEAVPSLTCRDFRRS
DLALVPSLFKKGLDNFLVVFGDPYPGHRIEDYDFRKTEELIRGVLSAFDGPRPCIGAVTN
QYAEDQERETSRTVRKVDAGADYVVTNTAFDDDLVLDHVDRLRSKGLKAPIFVQVSIPSG
LKNLLFVSQKFGIPVPEKVRQTLSRNPFGGGIRIAADAYTALRTEVNGIHFSYLHRSHNP
IPAYTHLLDAIETDGQLTVSIQAALIQ
>A0A6I5RML0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas laurentiana|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSTNDLRTLLAQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIRKESGDHFHIEVAAYPEMHPQARNFEDDLANFARKVKAGANSAITQYFFNADSYFY
FVERVQQLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDAKSIQAFG
EDVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7W1D5H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MHESGTETLARLLANPVLEVFPSSGIEERVAGLPDGTRISVTCSPARGVDATLALSGSLR
REGLNVVPHISARLVDDHQHLDAICRRLTELGVAEIFVIGGDLKQPAGRFSSTHELLAAM
AEMGHSFGEVGVAAYPEGHPSLSDETLWEHLRAKQPLATYMVTQMCFDAGAILAWIERAH
REGVTLPVVIGVPGVVQRRKLLGLSLKIGVGDSTRFIAKHTDLTAKLLGSGRYSPEDLVK
RLAPDAE
>A0A7K0XYM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MEMRLEKRMYSFEFFPPKDLAGEERLWQALSS
>A0A7V9BQJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSRQRSSAPPPPDPPPSFLDAGGFRVVCEIEPPRKPDIEHVRRQITVLNPVVDAFLIPDS
HLGRATVSSVAVAHEVAYLGGLGVACLNARDRNLLAFRRDLLTAAAYGVDHFLFVYGDPP
KEGRRAEDLTVRGMIDEIHAYGGGPLFHGFSDFRIGTVAKSNRALAWRTRADFLFTQITY
RFDRLLSWRESLDYPGRVYAGVLVLASTRMAQRINASLPDVHIPDEIVDKLDDHPDVGLD
LALEQIEEIKRSGAFDGVHLVPVSRYREVASRLARDG
>A0A3Q9JGZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Entomomonas moraniae|TrEMBL
MNRTDKLFSFEFFPTKTEAGLEKLLDNAKLLTKSCQPNFFSCTYGAGGSTRDRTLETVLQ
LTKKTQVSTAPHLSCVGDSKESLRNLLQHYKQEGVNRIVALRGDLPSGMGTASGELRYAS
DLVSFIREEMGDHFHIEVAAYPEVHPQALNMEQDLLHFVNKVNAGATGAITQYFFNADCY
FYFVERVQKMGITIPITPGIMPITNYSRLARFSDSCGAELPRWIRKQLEAYADDIESIQA
FGIEVITSLCEQLLAGGAPGLHFYTLNQAEPTLAVWKNLI
>A0A523RXS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MNLREKLAANKFVITVELDPPKTLNLDKILTEVNSANFRKIVDAVNVTDCPLAKLRMSPI
ALSHIIQEKIGLEAIFHITCRDRNLLGLQAELLGASALGVRNILALTGDPPEVGDYIMAT
GVFDVDSIGLVRMVNKLNNGYEYSGNELKDKTDFFIGIAVNPTAQDLTKEIKRFEGKVSA
GANFIQTQPIYDIGLLEKFLKLTAHINIPKIIGIMPLKNYKMVKYLNNNLPGIFVPPEVK
ERMRGKDVEEGVKISRELISKIRKFKEVAGIHIFPLRDMNLVCRLLN
>A0A538EGQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MCRASSEGDEVPAQNRFLERLENGPAIVGDGGMGALLSAAVPRLRSPEEANLRAPEAVVS
LHVSFINAGAELIETNTFGANRRKLAHNFLDDDLEALNSAGVKLAREAREVTGREVFIGG
SIGPLGEPAASRVRRELFAEVAAVLDGRGVDLFMVETFYDLEEVVDAVEAVRSVSSLPIV
ALLTFDESAETLAGVTAAEAAERLSELDVAALGANHGAGLLAALAALQNMRTNGKPLAAL
PNVGLASLAGGRVIYPHATPEYFAEFAAHARDLGAKVIGGCCGTTPAEIAAIRSAVEDER
RPRAPLVFESPELVVALGEEQRETGLSRALAAGEWVVSVQLDPPLGGNSAGLVEVAAALK
DSGRVGWVDINDNATARAGMSSLMVSATIERLAGIETIPHLTTRDWSVLGLESMLLGAHA
EGVRNVLAVTGDPPEVGDYPGSRGVYEIDAIGLTQLLTNLNRGEDFHGRPIDAPTSFFYS
VAVNPTPDDLEVEHERFQQKLDAGAKFGMTQIVFDFEYVDRFVDRLGGSWPIPVLLGIFP
LTSYRLAVRLHNEVPGIVVPQKLQDALEAAGSNAAEVGFAHARELIAAAREKAAGVYVVA
PFRRPLRVLELL
>A0A3D1Z6R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGFKEEIQSGNFVITAEVGPPKGTDISEMKHHIKSLKGKVTALNVTDNQSAVMRICTLAV
AKEIMDIGIEPIYQMTCRDRNR
>A0A537YZE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSWRFWKRRRASGLTEEQRAALKSLVADARYELIPLSSALESASALPPGSQVTVTASPSH
GIEATFDLAEAVAAQGHDVTPHLSAHMLSDRAHLARLLERARANGLRKVFVVGGDTRDRG
ELHDGLMLLRAMDELGHPFEEIGVPCYPEGHPDIPDERLLEVLREKQRYANAMTSQMSFN
PAAVTRWMGEVRDAGIILPLHLGVPGVADLPKLMRIAARIGVSDSARYLKKNKQLIGHLV
RGGSFGPDAFLEWLAPMLADPVADVRVLHVFTFNQVEQTAAWQRRMLEELGG
>A0A1H3Q1C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora pattaloongensis|TrEMBL
MALGLPSVLPGSQPSIGDLIRKTGPTFSFEFFPPKTADGERLLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAAAGVRNVLAVR
GDPPGNPMGEWVRHPEGVLYAEDLVRLVKQAGDFSIGVAAFPYKHPRSPDVASDTGYFVR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPIVAGVMPVTRMATIERSEQLSGAPF
PAALAARFERVADDPEAVRRLGIEQCSEMCRRLIDEGVPGIHFITLNRSTATREVWQNLD
VGARV
>A0A5C7NXY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSRSIAEHVAEGGRSYSFEFFPPKTDVGEANLWDAISALDPLRPDFVSVTYGAGGSTRDR
TIRLTGRIAAETDLLPVGHLTCVGSSRDELAEIVDQYADAGVHHILALRGDPPGGPGDRW
ESHPEGLEHADELVSLVNSRGDFTVGVAAFPEGHPEAATLDDDAKVLRTKQDAGADFAVT
QFFFSTSDYFDLVGRARQMGAELPIIPGIMPVTSVRQIERFADLSGAAFPPELAARFHEV
ADDPQAVIDLGVEVAAQMCQELLDGGAPGLHLYTLNRSTSTLRVFHELGLEQR
>A0A538GUX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MCRASSEGDEVPAQSQTRNRFVERLERGPVIVGDGGMGALLSAAVPRLRTPEEANLRAPD
AVVSLHVSFVNAGSELIETNTFGANRRKLSHHFLEDDLEAINSAGVKLARDAREMTGRDV
FIGGSIGPLGEPATSRVRRDLFAEQAAVLDGRGVDVFMIETFYDLEEAVDAIEAARSVSN
LPIVTLLTFDESAETLAGVTAAEAAARLMELDVAAVGANHGAGLLAALAALEQMGKNGKP
LAALPNVGLASLTGGRVIYPHATPEYFGEFAAHARELGAMVIGGCCGTTPAEIAAIRSAV
EEERKPRAPLVFDAPELVVALGEEQRETGLSRALAAGEWVVSVQLDPPLGGNSAGLLEIA
STLKESGRVGWVDINDNATARAGMSSLMVSATIERRAEIETIPHLTTRDWSVMGLESMLL
GAHAEGVRNVLAITGDPPEVGDYPGARGVYEIDSVGLTRLMTNLNRGEDFNGRPIDAPTS
FFPGVAVNPTPDDMGVELERFEQKLEAGAKFAMTQIVFDAEHLDRFVERLGGAWPIPVLV
GVFPLTSYRLALRLHNEVPGILVPQALQDELERAGSDAAEVGFAHARELIAASRERAAGV
YLVAPFRRPLRVLELLVD
>T0AX06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera terpenica 58Eu|TrEMBL
MSHARQFSVEISPLQGDQGRARLQQVITGLQAMGPEFVSVTYGAGGATEQASLAALEQVQ
AAGAVGVPHLSAIGMQRASVRALLAHYRALGVRRLVILRGDAPSGQRGSGDFLFAGELVR
FIRAECGAHFHLDVAAFPECHPQARNSDEDLRHFKAKVEAGADSAITQYFFNPDAYADFI
ERCAATGITIPIVPGIMPIGSFSRLVGFSEARGIEIPRWISMRMAAYGDDKASIRALGIE
LAVRLCERLLTLGAPGLHFFSLNDDARVAEIWRSLNLPSSGTGTGTAAAKVA
>A0A0D1EFH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jannaschia aquimarina|TrEMBL
MSAPAVSFEFFPPKSLQGSFRLWDTVRALAPLSPEWVSVTYGAGGTTRQLTREAVAAIGG
EFDLRVAGHLTCVDASREETLEVAEGFREAGVEDIVALRGDPPKGADRFTPHPDGFADSV
ELVGALAERGFRVRVGAYPDRHPEAADADADVAWLKRKIDAGAAEAVTQFFFDPETFLRF
RDRCAAAGIEAPIVPGILPVENWSRTRGFAERCGAVIPDELAAAFDVAERDGRADLFAIA
QCAELCDRLVEEGCGHLHFYTLNRPDLTRDVCAALGRVAAPSLEAVA
>A0A3S9F3N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M8A.F.Ca.ET.057.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHEVDAVIQEFTDMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVA
GSAAA
>A0A537WJD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
LQATDSPDPESVYRLADLLRGSVDAVNCTDNSAAHPHISPLAAGHLLLDRGVEPIVQLAC
RDRNRLALQADLVGAVALGARNVCLMTGDDVTAGDHPEAKPIYDIDAVHAIQIARIMRDR
GIYVSGRRLDRPLPLFIGAVENPFAPPHDFRPMRLGKKVEAGAEFVQTQIVFNLATMRVF
MARSGELGLLDRVFILPSVYVCRSAGAARYLRDMVPGIDVPDSVIARIEGVPSERQADEG
IRIALEIVEELREMRGVAGVHLISIKGDESIVRLVEEAGLLPRPAGFSVNGGLHGAE
>A0A537V4F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MLRHRARAHDRDRHRAARSRAACPDRVPRGGSRRADPRRGHGRPADEAGGQARDRSLRRD
GRDGAAPVVQCRPAGRRGGDALIHEQADIETVLHFPTRGRNLLRLQGDLLGAYALGIRNL
FVCVGDPVTIGEYPHGSNNVDVTATGLLSMITHAFNAGVDRSGTSIGAPTSFFAGAAVAP
SAPDLEREARLLARKAEAGARFVLTQPFYSIDPLLALRETYEKVAGEPLTVPVIAGVLPL
MMSRHAEFLHNEVPGIEIPEAARNRMRSAGDDDDRAWEEGAAMAIELIAALREEGVAGVY
VMPQFGRYDRAAEVVEAARGPATM
>A0A350SH59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MENLSSVKDESFDSIKKTTLQKKLENNEFAITCEIGPPKGIDITEIRETAEILKGIVDAV
NVTDLQSSVMRLGSLATCHLLLDYGIEPIFQMTCRDRNRLALQSDLLSAYVMGIKNVLAL
TGDHTTVGDHPQSKPVYDLDSVSLLWTMKKLESGKDLADKELKGNPVFFKGAVVNPGADT
EVSLQLQLLKMQKKIDAGAQFFQTQAIFDADTFENFMERIDKLDIITPVIAGIILLKSEK
MARYMNKFVPGINVPADIINKMENSQDKVSAMLEITQELIEKIKPMSHGVHIQALGWEKH
VPVLLKNLNV
>A0A2C8F3P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio profundus|TrEMBL
MRVCDLIDKKSPFISLEFFPPKEKDAWPGFFDVVEKLKELAPLFASVTYGAGGGTQDNTL
EIATRMKRDHGIEPITHLTSVGASAKRLDDFLLKLREANIENVLALRGDPPRGVEDFDFD
KQEFRHATDVIEFISKRYPEMCVGGAAYPEPHFESPSIQSDLEMVNLKVQKGAKFLVTQL
FFDNRLYFDYVERLKQMGSEVPVIPGILPIMSLKSAKFILSLCGAAIPGKFLSALEKAHE
EGGDEAVYSLGMEYAIKQSQELLDGGAPGVHLYTLNRAKACLDIGRNLKIEERLERE
>A0A537VD16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSWRFWRRRRASGLTEEQRAALKSLVADARYELIPLSSALEHAAALPPGSQVTVTASPSH
GIEATFDLADAVAAQGHDVTPHLSAHMLRDRAHLADLLERAQANGLRKVFVVGGDTRDRG
ELHDGLMLLRAMDELGHPFEEVGVPCYPEGHPDISDERLLEVLREKQRYANAMTSQMSFN
PAAVTRWVGEVRDAGISLPLHLGVPGVADLPKLMRIAARIGVADSARYLKKNKQLLGHLV
RGGSFGPDEFLEQLAPMLADPVADVRVLHVFTFNQVEQTAAWQRGMLDELSA
>A0A1A2LLA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. E3251|TrEMBL
MSAGLECPKRMEFGPCGGVRPDGQCEMRPGACAFDDVVAWSGPQPAARPARAPLVLTDFS
CSPFDRRDVAATAAALAPGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDRN
RVLLEQELRGLRSINVETVLCVTGDGRGYDVRPDVTQTFDLDGPRLASLAASTGVVAAVP
ETPTAPPVHARPARLVEKQRAGASLAVLNHVPRPEIVADFMTMARAVGLAIPVIAAVAVF
TDNASAAVLEGLPGLKLDQAVTERVLGAPDPVAAGIAAAVAEARALLSIEGVDGVNVSGL
ASASGGRAGAEIKAEVGRRIRVGASS
>A0A7Y0QRE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. SF27|TrEMBL
MSPPTPTVPHFDAEITNHPALSYELFPPRNAQANEALWRTIRELEGTAPDYVSVTYGAGG
SNQGTALELLERLQNETRLRPLAHLTCVGSSGPELARTIEAILGRGVRGILALRGDAPAG
SSGRPSGELRYAQQLVELIRRIERRRTAHLAAGKVAIGVAAYSSRHPESPSFEHDVEVLL
AKQSSGADFAITQIFFDANDYSSLLRRAQQAGVRIPIIPGIMPLTSVRRLDRLAQLAGID
VDLAVRDRLASAGDDSTRQRIGIQATVDLANAALDAGAPGLHLYTFNEHVSALQLLEKLQ
LPRPTAPVRHKVLARA
>A0A8C7HWY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus kisutch|TrEMBL
AVNEDNYTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTESGDH
WFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVN
YCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYATDL
VKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADTFLK
FVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYG
IEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHPKRK
VEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALL
KMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVNRRG
VLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNY
HIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEQTAEQ
PNDEQSDKEQPGK
>A0A7G6AGU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHISPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDIIDKVLHFSGKARDIQDFELFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQTLACVMPLTLGRANYMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVK
TGKEFTPEITRFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENSLVAK
VLIKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVAQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A8C7HVV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus kisutch|TrEMBL
LTCAELSNGSITPAVGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTESGDHWFS
LEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYATDLVKH
IRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVR
DCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGIEQ
AVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHPKRKVED
VRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMW
GEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVNRRGVLT
INSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIV
NVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQWAKLYED
ESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEQTAEQPND
EQSDKEQPGK
>A0A0B7JLQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bionectria ochroleuca|TrEMBL
MHIKQMLTEAEGTGQPSFSFEYFPPKTAQGVQNLYDRMGRMYNFGPKFIDITWGAGGRIA
ELTCEMVHQAQAVHGLETCMHLTCTDMGMEKVNDALKRAYKAGCTNILALRGDPPRDQEK
WTATEDGFQYARDLVKHIRKEFGDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDEGASF
IVTQMFYDVDNFIRWVKKVREKGIDIPILPGIMPVATYASFLRRANHMQCKIPQAWLDRL
EPVKNDDVAVREIGTTLVAEMCRKLLANGIFHLHFYTMNLAQATRMVLEELQWTPSAERP
LQPALPWKPSKGLGRRDEDVRPIFWRNRTKAYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPQSYRDIAELFVKYLKNEIETLPWSESPLTGEADAIRENLVN
LNRRGILTVNSQPAVDGVKSSHPIHGWGPSNGYVYQKSYLEVLVHPRLYQELTSRMAKQE
DLTYYAVTKSGQLETNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFQLGMDW
AKCFDSGSASRKLIEHIMTDWHLINIVNNDFHDNESIFKLFDGLEIDFKELESPFEGQTD
NQESVTNGSHASQAIPKEAAALVAN
>A0A386HU03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachidicoccus soli|TrEMBL
MKITEHIHQAKKPLISFEILPPLKGKDISSIYNHLDPLMEFKPSWINVTYHRSETIIKKK
EDGSFEKVPIRKRPGTVGICAAIMNHYGVDAVPHIICGGFTKPDTEDALIDLNFLGIQNV
LVLRGDAEKHAPNFEPEKGGHRYAIDLLKQVSQLNNGIYLDENIRDGGKSNFCMGVAGYP
EMHLEAVSYENDLKWLKAKVDAGAEYIMTQMFFDNQKFFSFVKDCKAIGIHVPIIPGLKP
LTTQKQLSILPPIFNIDIPNDLATAITQAKTDEAVRQVGIEWLIQQCKELKEFGVPVLHF
YTMGKAHNTYDVVKQII
>A0A2N9LJW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MPLDRVFSVEFSPPRNAEGVEKLRATRAELAHVAPAFYSVTFGAGGSTREGTLSTTLEIY
AAGLHAVPHISCIASTRASVRELLCTYRDAGIHHLVALRGDAPSGVAGSAGEFRYAVDLV
ELVRAEFGDWFRIEVAAYPEIHPQARSPAEDVQNFVRKVRAGADSAITQYFYNDDAYYRF
VDEVAGLGCTVPIVPGIMPITNFTQLARFSDNCGAEIPRWIRRRLESFGDDRSSIRAFGA
DVVAALCERLLAQGAPGLHFYTMNMAAPTLEIWRRARLPVPPR
>A0A212K1G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured delta proteobacterium|TrEMBL
MVKIIDALRERTRPFYSLEFYPPKDKAEWPAFFEAVDKLKALDPLFASVTYGAGGGSQDN
TLAVAAKIRETGITPMPHLTCVNATRERLADFLRELGTIGVDNVMALRGDAPQGEGFSWE
AGEFRYASDLVAFARREFPEICLGVAGYPGAHPESPSFSSDILHTKAKLDAGADFVVTQL
FFDVREYFALVEGLRAMGVTKPVLPGILPIQSLESIRRILQMCGANIPGKLYLALEDANK
TGGAKAVREVGIRFAVEQIRRLIDNGAPGIHLYTLNRAGMCLRIAEEAGIA
>A0A518AGE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia panareensis|TrEMBL
MRISEIYRSGTFGLSVEIFPPKSESGDAELFRTLEDLIRYQPAFVSCTYGAGGSTSKRTI
ELCDIIQKQLQTTATAHFTCVGSTREQLLAWLQEAADVGITNIMALRGDPPKGAETFVPA
DGGLKYASELVTLIRENFPDMGIGVAGYPEVHPEALTPQADLENLKRKIDAGGDAVYTQL
FFNNEHFYRFRERCGQAGIDCPIIPGIMPITEFRRIQRIMSMCSSEFPADLVNRLEAAQD
DLDAQFEIGVEYAINQCKELIDSGVPGMHFYVLNRSQACKRIFDALGWHEDQA
>A0A3S1ETH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2C.T.Ca.TU.002.02.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDTVIREFADMGVKRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A257FWC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium PBBC2|TrEMBL
MEGDVMRALNLPISLEFFPPKTPEGAEKLRLVRQQLYALKPEFCSVTYGAGGSTQEGTFA
TVGAIQNEGVAAASHFSCIGATKASVRQELATLKAMGVKRLVALRGDLPSGYGAGGEFHY
ASDLVSFIRAETGDDFHIEVAAYPEVHPQAKSPESDLQAFATKVKAGANSAITQYFYNAD
AYFRFVDDAHKLGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGYSDDIESI
KAFGLEVVTDLCEQLIRAGVPAIHFYTMNQSAATMAILSGLQSR
>R5DUS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:86|TrEMBL
MKISSIVGKDKLTLSFEVFPPKTDSDFEKVKEAAFGVAAIKPAYISVTYGAGGSTSTNTL
AIAKGIQEKYGVATIAHLTCVGASKDSIIKSLSDMRDAGIENVLALRGDKPKWFDGEPFK
EYKYASELVSTIKEFGGFSVGGACYPEVHPDSANRQEDIINLKKKVDAGCEFLTTQMFFD
NSVYYDFVENVRKAGIDVPVIPGIMPITRESQIENVIKLSGCKMPQQFIKIVDRFKEDKA
SMKQAGIIYATQQILDLYANGVKNVHVYSMNDSSVAGAIYNNLSDILSM
>A0A3E0JML7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillaceae bacterium|TrEMBL
MKPVLRDALRTAVLTGDGAMGTYLHQLGYPIGVSYEEFNMTRPETIASVHKQYYDAGARV
IETNTFSANAERLARYGLEDEAARINREGVRIAREAVGADAWVVGAVGAIRTGRLTAVGT
PAVERAFAEQIDALLDAGVDGILLETFYDLDELLLALRLVRDRSDVTVICQLAAVGTGLL
YSGLPIGEAFRRLEDAGADAVGFNCESGPNGILHAIDALDGAVKLPISVFPNAGGADYVD
GRYTYAAGPAYFGDCARRFADRGARLIGGCCGTTPEHVAAIAASLAGWTPGAAAPERTAE
AVQASAPQIRVNAEPAPAGGGEAPGGGDGPTIVELVRQRPTVIVELDPPRDLDTSKFMAG
ARALRDAGADALTMADNSLAVTRMSNLALGAIVKEQVGIRPLVHIACRDRNLIGTQSHMM
GLHALGIDHVLAVTGDPAKFGDLPGSSSVYDMTSFDMIRMIKQLNEGIAFSGKPLKQRAR
FVVGAAFNPNVKHLDKAVRRLEKKVESGADFIMTQPVYDAALIERIADATRHIGVPIFIG
IMPLASGRNAEFLHNEVPGIELSDEVRRRMAGLEGEAGRTEGVRIAEELLDAALSFFNGI
YLMTPFMFYDMTAKLTGYVRAKASVKTSVISCSSGENELK
>A0A6G2MYZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4946|TrEMBL
MGTDLLDDFSLEMTGKDVPALEEARGSIPQGTRINVTFLAGEDHATRLAAARAVRGLGFV
PVPHISARRLPSSAALEGFLAGLAEDGTADNVFVVGGDPARPEGPYEDALAVLRTGLLER
YGVRHIGISGYPEGHPAISGPALWSALTDKARAIGAGPFTGDVITQFGFDADPVLDWLAA
VRARGVDLPVRIGVPGPAGIRRLVGYATRFGVTTSASVARKYGFSLTNLLGTAGPDRFLH
ALGERYDPARHGVVKVHFYTFGGLRTTAEWVGGFRERTR
>A0A435AGC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.11.2.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A1I5ILZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. tf2-5|TrEMBL
MYFCKILYIYAVMTVADYIKKQDTGERRFSFEVLPPLKGNGTEALFETIDKLVVFNPAFI
NITTHHSEYVYKELENGQFERQRIRRRPGTIAIAAAIQQRYDIPVEPHVICSGTTVEQIE
YELLDLQFLGIRNLMLLRGDKAKEDSRFTPTPGGHAHTTDLIKQVVRFNEGFFADGTPIK
HPGPKFDFGVACYPEKHEEAPNLERDMEYLKQKQDLGAQYAVTQLFYDNEKYFEFVKKAR
QMGITIPIIPGIKPMAKLSQLTVVPKTFHCDIPEALTKEIVKCKTDEQARQLGIEWTTQQ
CQELYEHGVKNIHFYTVSAVDSVVEVAKRLL
>A0A1V5U952|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dependentiae bacterium ADurb.Bin246|TrEMBL
MFETLISKLQEDKYLTLETTPQHEPSMHNIVEKIKKFKIDSKVDGFTCTDNPLAKLKYNS
LFAALKLQQEFKKPVIATMTMRDRNKIALQSDLLGANDFDIRAILALTGDPANMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFAVVNAYAKNFGSLEKKMHLKI
QNGAVGVITQPVFDIENVKKLLENFENAKENVEGDKRKAQLIFGVFPITKLRTALFLSAQ
VPGIHVPQFWIDELEKAHNISEEEEYKVGMQLSKNLFDEINRIHPKIHLMTANNKFEVAS
EILA
>A0A2K0XW32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. SA916|TrEMBL
MTLSFPSVEEARRALDAPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIQTLTPLAPKFV
SVTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKAEIDGVADAYWEAGVRHIVA
LRGDPPEAGAKFEAHPDGYKGAAELVEGLVKRHPFEISVAAYPETHPDALSARGDIDNLK
RKLDAGATRAITQFFFEPDTFFRFRDTVAAAGIDADIIPGIMPVSNFAAVQRMSAMCNTD
VPGWMGKLFEGLDDLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPATLEKTA
>A0A7Z8D1Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus mirabilis|TrEMBL
IKDIKERTGLEAAPHLTCIDACREELQHIAQDYWQSGIRHIVALRGDLPDNSQKPDMYAV
DLVHLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKKKVDAGANRAITQFFFDVESYLR
FRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMFDGLDNDPETRALVG
ASIAIDMVKILSREGVKDFHFYTLNRSELAYAICHTLGVRPQLAKV
>A0A009G3L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 118362|TrEMBL
MLVEYLTSLHEIYPVRHEFAGYPAAITLADRVHSDHDIAPLEASKSYPDSVEKVLHFSGK
ARDIQDFERFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICEH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVKTGKEFTPEIARFSR
QPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENSVVAKALLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKQT
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A6M4WUU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces asoensis|TrEMBL
MQPASTVRTAVGTSLLDDFSLEMTGKDVPKLEEARDSIPQGTRINVTFLGNEDLRLRLDA
ARAVKRLGFVPVPHISARRLGSRDDFERFLAGLRADGTSDNVFLVGGDPAHPEGPYADAL
SLIDTGLLREYGVRHVGIAGYPEGHPAIDGTALWSALRDKHAALAAQPLEAGVITQFGFD
VDPVLAWVEEVRSRGVALPIRIGVPGPAGVRRLMAYAARFGVGTSASVVKKYGFSLTNLM
GTAGPDRFLRALAAAHDPARHGELKIHFYTFGGIKATSDWAARFRKDSLA
>A0A7W9BTF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas prati|TrEMBL
MTLSVTELEEARCALDAPLFADLAGDAKVSFEFFPPKTEKMEIALWNAISTLLPLKPDFV
SVTYGAGGSTRERTHATVARIASETDTPAAAHLTCVDASKDEIAEVARAYWDAGVRHIVA
LRGDPPREGEKFAPHADGYQSAAELVAGLSRIAPFEISVAAYPEMHPEATCADTDIDNLK
RKIDAGATRAITQFFFSPDAFFRFRDRATAAGITADLLPGILPVSNVAQTRKFAAMCGAA
IPPWMDRLFDGLDDHPATRQLVAATVAAEMCRKLYAGGVRDLHFYTLNRAELAYAICHLL
GKRPVVGERALELAA
>A0A7G8DHP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. BIOS-E4-1|TrEMBL
MGSALQRSLEAGAVTVTAEVMPPRGGDPSHTLAMANLLRDWVQAINVTDGSRAVMRMSSL
AVCRLLLDVGLEPVLQMAGRDRNRIGIQADLLGAHALGIRNLLCLTGDSVKAGDQPAVRP
VHELESVRLLQQVSAFNRGEDPVKESLPDGPTALFAGAAADPHCASWSGLKRRLERKREA
GARFVQTQMVMDPQVLERFCREMAAPMEMPVLAGVFLLKSARNASFINQKVPGANIPDSL
IARLDAASDPAAEGIAIAAEQVRQFAGIAHGVHVMAVRAEERIPEVLERAGLSSQQS
>A0A7W6JWI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas kyeonggiensis|TrEMBL
MTILDPLAAPLFADVAGDIDVSFEFFPPKTEKMEETLWESIETLSPLGPRFVSVTYGAGG
STRERTHNTVARIARETGIPAAAHLTCVEATKEEIDQVAQEYWEAGVRHIVALRGDPPRA
GEKYSTHPGGYENAADLVAGLRKLHPFEISVAAYPECHPDSPNPSADIENLKRKMDAGAT
RAITQFFFEPETFFRFRDDAAKAGIDAEIVPGIMPVMNFASVQRMSAMCGTDVPAWMGRL
FEGLDAHPAARQLVAATLAAELSRKLYAGGVRQFHFYTLNRAELSYAICHLLGVRPKVGA
EVVAA
>A0A1G9EA60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maridesulfovibrio ferrireducens|TrEMBL
MKIVDLIEKNKPFISLEFFPPKDKESWPAFFEVVEKLKVLNPLFASVTYGAGGGTQSNSL
EIVKQMKQDMGVEPLAHLTCVGATPENISYFINSLREAGVENILALRGDAPKDVEDFDFN
TQVFKQGSDLVTYVNDQHPGMGIGVAGYPEAHLESPSIKEDFKWMKYKVDEGGQFILTQL
FFDNRVYFDFCERLSEMGINVPVIPGVLPIMSLKSAKFILSLCGATIPGKYLSALEKAHA
DGGDEAVYRLGIDYATKQAQGLLDGGAPGVHLYTLNRAKACLEIGQALKF
>A0A0R2VC10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium BACL12 MAG-120802-bin5|TrEMBL
MKVTERIHQATSTLLSFEVLPPLKGKSVQSIYDILDPLMTFNPAFVNVTYHRSEYMYKKR
SEGIFEKIYTRKRPGTVGICAAIQFKYKVDAVAHLICGGFTKEDTEDALVDLWFLDIENV
LLLRGDAARNERVFEPEPGGHAHAIDLVKQVVNMNKGLYLEEEHQGGKTDFNIGIAGYPE
KHFESPNMSTDLKVLKEKVDAGAHYIVTQMFFDNQKFFAFEKKCREAGIHVPIIPGLKPL
TAAAQINTIPRIFHVDIPEALADAVEKAGSAEAVQKVGTDWCVEQSRELKAAGVPCLHYY
TMGKIDVMRSIMQEVF
>A0A435VHS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.003.02.2.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>M4CKS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica rapa subsp. pekinensis|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRANGIQNVLALRGDPPHGHDK
FVKVEGGFGCALDLVNHVRGKYEAHPDVIGENGLASDEAYQSDLEYLKRKVDAGADLIVT
QLFYDTDVFLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMTGFCKTKIPAEVMAALEPI
QDNEEAVKAYGIHLGTEMCRKILAHGTKSLHLYTLNMEKSALAILMNLGMIDESKISRSL
PWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSASYGALTDHQRFR
ELCLGNLKSSPWSELDGLQPETKIINEQLVKLNSKGCLTINSQPSVNAERSDSSTVGWGG
PGGYVYQKAYLEFFCSKEKLDAIVEKCKALPSITYIAVNKGDNWVSNTAQSDVNAVTWGV
FPAKEIIQPTIVDPASFKVWKDEAFETWSRSWANLYPEAADPSRNLLEEVKNSYYLVSLV
ENDYINGDIFSVFADL
>A0A2G9DJV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. JV178|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVRATEQIAADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMADWVPHPQGLTYAAELVHLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFHPDSYLRLRDAVAKAGCETPVIPEVMPVTSVKMLERLPQLSNAAI
PDALKERIVTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A395GUX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus ibericus CBS 121593|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLGKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEATDGGFRYAKDLVNYIRSKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGASF
VITQMFYDTDNFIEWVRKCRDRGITVPIIPGIMPIQTYAAFIRRSNWTKVRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVSFLEGKLARLPWSDTPITTEANAIKESLVE
LNKKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLLGELIGRIEKNG
DLTYHAISKDGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQGVMDSWYLVNIVNNDFHNTSNLFDLFKDLDVQDLDTEISVENGESK
AHTNGAANGTTNGVLNGAAPETAVKN
>A0A4Y8K7C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Hh7|TrEMBL
MSACNARPAFSFEVYPPKSAAAASALMSTIDHLAAAGPEFISVTYGANGSSRNSSLDVLR
YIKNHTEADAMAHLTCVGSSHAEASRLIREFLDAGIRSFLAIRGDAPPGAVEGDNTFLGD
LHSAGELVQLIHRVQTERVPYIETVIPGLPGARGVKTERSKVRIGVAAFPNGHPNSRSVS
QDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLFPILPGIMPVTSPNRLRRI
LQLSGEKLPAGLSIDLEVEPTEEGQRQIGIDYAVRLGQDVLAGGAPGLHLYAFNQHDTVL
QVLEGCGALPVPAVML
>A0A1Y4GS78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Barnesiella sp. An22|TrEMBL
MKVADLLKNNGSTGFSFEILPPLKGSSIEKSFKTIDTLREFDPLYINITTHRSELVYKDT
PDGLFRRVSERSRPGTVAVAAAIKNKYQIPTVPHMICSGFSAHETEYALIDLNFLGICDL
LILRGDKAKHESRYTAVPGGYEHAIELEQQVNRFNEGFFIDGTPMDVVSSRPFSYGVAGY
PEKHDESPNPDEDMKWLKAKVDTGADYIVTQMFFDNSKFFNFVDRCRAAGITVPIVPGLK
PISKASQLTLLPRVFHVDIPDALVREVAKCKDDSQVKQVGIEWCTAQSRELKARGVPSIH
FYSLMAVDSVYQIAKQVY
>A0A421BAN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinokineospora cianjurensis|TrEMBL
MTTVVQRIRVGRPVFSVEFMPPRDSADEQRLWNAIRELEGLDPAFVSVTYGAGGSSRDRT
IRTTGRVARETTLVSMAHLTAVDHSIAELRNVIGWYAALGIRNILALRGDPPGDPNGEWS
AHPDGLHYADELVRLVRELGDFCVGVAAFPYGHPRSADLDADTENLVRKLQAGADFAIAQ
LFFEPEDFLRLRDRVAARGCDADLLPGIMPITTRKTLAKTIELSGAPVPARISALLEPHT
DAKSFRAAGIDLATEVSERLLAEGVSGLHFYTFNRSKATKEVVNRLGLVPART
>A0A0P9LRH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. ciccaronei|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>A0A223E108|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeribacillus pallidus|TrEMBL
MSIYIGNRLVSANDFTVTSEMVPPRSWNPSPLVEQAVRARGYVDAVDLSDNLLAIARLTP
VVGAFFIRQVGLEPIVQINLRDRNRMGIQSDLMGLAALGVKNITILGGYPAKIGTEPNAK
EVYDLETMELVRYVRRFVDEGKLFDNTVMEEAPEMTIGVVENIAGKPVKELIDRLEAKID
AGANFVRTQLVFDIELLEEWMEEARRRGLHERSYIMASILPLRDADHVDAVLKIPGIAIP
DKIIKRIKEADSPDEGMKMVVELIHKLRTIDGIRGIHIRPLGGMDRYVSSIVKEAGLMNR
KQEKVEEYAS
>I0V6F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora xinjiangensis XJ-54|TrEMBL
MRTVVERLSSARCPTFSVEFFPPRDDADEAVLWRSIRELEPLDPAYVSITYGAGGTSREG
TIRNIARVATDTTLVPMAHLTAVNHSVAELRHVIGHFAAVGVRNILALRGDPPGDPMGEW
VPHPKGLMYAEELVRLVRELGDFCVGVSAFPYGHPRSTDLDTDTRYLVRKLDAGADFAIA
QLFFEAGDFLRLRDRVAAAGNAALMLPGIMPLTTPRTWRKTIELSGATPPSWLVERLEPL
SDDPKAFRAEGLDVITELCERLLAEGVPELHFYTFNRSKATRELVDRLGLRTPRVEPASA
GS
>A0A1X0HB58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium monacense DSM 44395|TrEMBL
MTSTDLQCPKRMQFGPCGGVRPDGQCEMRTGPCAFPDVVPWSGVEPASRPAQAPLVLTDF
SCAPFDEDDVAATARILGRSCDAVLVGEHQNRPDFPPTLMGRLLLEAGVTPWITLSCRDR
NRIVLEQELRGLRSLGVGTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGMVPAV
PETPTAPPVHARPARLVEKQRAGASLAVLNHVPYPDTITDFMATARTAGLSMPVVAAVAV
FTDVVSAAVLQGLPGLELDQSVVDEVLGAADPVSAGIAAAVAEARALLAIDGVDGVNVSG
LASASGTRVGAEIKAEVGRLVKAEVGA
>A0A2A3M5I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas plecoglossicida|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSTERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSRQATPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPMWATRLGSQVLHKVEHAVKHPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTALLTERLIPCIELETRHRSSWPQWFQAQTP
RQLSPQPAPRTQPES
>A0A8H5TAG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium heterosporum|TrEMBL
MHIKDMLSEAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFRYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGVTIPILPGIMPIATYASFLRRANHMQAKVPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELEWAPCAERP
LQHALPWKQSKGLRRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPQTIQDIAQLFVRYLHNEIESLPWSEAPLTSEADEIREGLIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPGVFGEMIARIENHP
DLTYYAVTKDGELRTNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLATPATPLSKST
NNGAIETEPVANGTAATALAN
>A0A1Q6DLW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium DB1|TrEMBL
MKVAFSDYIKEHVILGDGAFGTYLFEKGIDFGKNIDLLNIKNPDLIYSVHEEYIRAGSQL
IETNTFGANSFKLQAAGKEDQIAEINQAGARIAVKAAGHDAYVAGSVGPTGIEFPLISGD
ITVEDIKAAFALQMGALVEGGVDLLILETFTHLEEMLLAIETARQVGSGLPIVAQMVYPA
QGRTARGIDALECARAALAAGATVVGTNCGRGIDAMSMAVSRLMPLADEHVPLSAFPNAG
LPEVMGHRMVYPAQPSYMARRAAEMLKMGVRLIGGCCGTTPAHIHEFRKTLKLRHKKTLD
AKSVPAAPLEETPAAPAGLKRSGRGAFLDNLPEDRLPVLVELDPPTHLDIDNVLAGARSL
AASGVDAVTLGENPLAILRAGNIALAHRIREETGVQVVLHQTCRDQNALGLQSHIMAAHI
LGIEAILAVTGDSASSTDQPGVSGVFDVNSLGLIRMISQFNQGLNMAGQSIKKPTRFSIG
AAFSFRPSNPTMQITRLERKAAQGAHFVMTQPLFDKNAVEAMVEQTSHLNLLVFPGIFPL
ISARNADFLHNEVPGISIPAEIRKKLWSYAEVADQRKAALEITEKLIADLASFVDGLYII
SPLNKWEIAENFVKQIRLAGWKGSGRAAMKTAP
>A0A559TPN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. BK340|TrEMBL
MNPAATVPPAVGTSLLDDFSLEMTGKDVPKLEEARDSIPRGTRINVTFLAGEDPDMRLAA
ARAVKRLGFVPVPHISARRLPSQRHLEEFLAGLAADGTADNVFVVGGDPARPEGPYEDAL
AVIRTGLLERHGVRHVGISGYPEGHPAITDHSLWSALGDKSAVLGAQRIAGDVITQFGFD
ADRVLGWVADVRARGVTLPVRIGVPGPAGVRRLVTYATRFGVGTSASIARKYGFSLTNLM
GTAGPDRFLHALAQGYDPARHGEVKVHFYTFGGLRTTAEWIARFRRPDRGA
>H0X153|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Otolemur garnettii|TrEMBL
MDHRKAKVLPAMHHCPSLGMGASEASSVRLSVSPSISRNSAMVNEARGTGGFNLRSEGSS
SGSENSKDSSRCSTPGLDLERHEKLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQEEITG
HLHKAKQLGLKNILALRGDPTGDQWEEKEGGFNYAVDLVKHIRNEFGDYFDICVAGYPKG
HPEAESFEADLKHLKAKVSAGADFIITQLFFETDTFLHFVKACTDMGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHF
YTLNREMATTEVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFDVFVHYLS
GEPNQNGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGRPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSRTIIQHIHDNYFLIN
LVDNEFPLDSCLWQVVEDALELLSRPSQSERAVEAS
>A0A0L7CVQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium breve MCC 1114|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGSHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQAVGEFNHASDLV
SYIRSVKPDLKVFGACYPEGHYQADTIDRDIENLKIKVDAGATHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>Q92NK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium meliloti (strain 1021)|TrEMBL
MNGRTPYPVDCDGLRFSFEYFPPKNDEMETQLFQTVTALSVFAPAFVTVTYGAGGSTKAR
SLTTVKRMIGEMEIANTAAHLTCVGAPKAEVDAVIDEFLACGVRHFVALRGDPQGGIGSV
YEPFPGGYENAAALVKALRARGDFEISVSAYPEKHPESPDVAADIDMLKRKVDNGATRAL
TQFFFDNDDFERYLERVRRAGIAIPIVPGILPINNLTQVQKFAGLCGARVPESIVSRLGP
IDDQPEERFREAAHIAAEQVADLVRRGVSDFHLYTMNRPQLITAVCELMGYDPEIAPAQP
ADTERSVRAVARA
>A0A172QUP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium crudilactis|TrEMBL
MSSTNIPASSQWAISDVLKRPSPGRVPFSVEFMPPRDDAAEERLYRAAEVFHDLGASFVS
VTYGAGGSTRERTSRIARRLAKQPLTTLVHLTLVDHTHEEMRDILDGYLELGLTNLLALR
GDPPGDPLGDWISTEGGLNYASELIEMIKSTPRFEQFDLGIASFPEGHFRAKDLEEDTKY
TLAKLRGGAQYSITQMFFDVEDFLRLRDRLVAADPIHGAKPIIPGIMPITSLRSVRRQVE
LSGAQLPSRLEESLVRVANGDEQANKDEIRKVGIEYSTNMAERLIAEGVEDLHFMTLNFT
RATQEVLHNLGMAPAWGAEHGQDAVR
>Q92XS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium meliloti (strain 1021)|TrEMBL
MVAALAAANGICLFENPGEAMTNPAEACTDTRVHPVDGADTTISIELAPEQVRNFAPQAD
TLALGSRVFLTHLAGKPEVLQVEAAARIIEMGYVAVPHLAARNFKSERDYISHVEAHSRN
GIDEVLFLGGNPALFPGPLGESAELLAHPVLSDSSIRTAFVAGYPEGHPNISEARLKDAL
KRKLEICARRSLEPRIVSQFAFDGAMIGAWAKRLHDDFPEVPIHVGLAGVTSLTKLIRFA
AMCGVGPSIAALRRSVSGLLNIVADRNPADVIDAVSKAYPDTVTPLHLHFFPFGGWEKTL
TWLGDYRVARQLQAGVR
>A0A3C1IEP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTPPQISFEFFPPKNLESSFRLWDTVQVLAPLEPRFISVTYGAGGTTRDLTRDAVSTLHK
SSGLRVAAHLTCVNASRQETVAVARSFAAAGISDIVALRGDPPKGVDGFTPHPEGFQSSL
ELISALAQSGDFTLRVAAYPESHPEAESPTADIEFLKRKIDAGASEALTQFFFEAETFLR
FRDACDKAGINVPITPGILPIENWQGTRRFAKACNAKVPNWLTDAFSKAERDDREDLLAT
AVCTELCSQLIDEGVDTLHFYTLNRPDLTRDICHALGITAAVKLEKIA
>A0A840UQW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoprunum benzoelyticum|TrEMBL
MSTETKYSSGSNLEKVLKSGQFAFTGELGPPRGTDVDEVREKARFLKGHVDSVNITDNQT
AVVRMSSWAASLIAIDEGLEPNYQMVCRDRNRLAMQADILGGYALGIRNMLCLSGDHQQF
GDHPDAKGVFDIDSIQLIALVKQMRDEGRFLSGNEIHKPPKMFIGAASNPFADPFEWRVH
RLAKKIEAGADFIQTQCIYNMPKFREFIRLANEEGLTEKVYILGGVTPMKSVGMARYMAT
KVPGMDVPEEIINRLKGVEKSKVAQEGINIACEQIEEFKAMKGVHGVHLMAIEWEHMVPQ
IAEQAKVLPRPVFD
>A0A553LK03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. LEMMJ02|TrEMBL
MGLLDKLKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIAAMAKALSDRTPVTEKTVKRRAVSVS
VQADRPAPSPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKEQLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACGGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A808IIQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. Crenshaw|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A6F8UUY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. ANAM02|TrEMBL
MNAFRPSRHGSRRPRVSFEFFPPKTEEMELALWESVRRLEPLGPSFVSVTYGAGGSTRER
THATVKRMVEETRLSPAAHLTCVSASKAEIDEVIRSYWDAGVRHVVALRGDPAGGLGTAY
EPHPDGYHQTSDLVAGLKRIGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRARGIEIPILPGIVPVQNFKQTANFARKTGASVPQWLADRFEGL
EDDAATRRLVAAAVCAEQVLDLIDRGATDLHFYTMNKADLVYAICHLVGLKPEKPAAQAV
AAE
>A0A8D5HJ64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus hoagii|TrEMBL
MTFDAVRGRNSAGFVTQTPSIVDRIRSSEASKSGRIPFSVEFSPPRDEAAEARLWRAVRE
FERLGPAFVSMTYGAGGSTRDRTVRVTGQLADDTTLLPVAHLTAVGHSIDELRAMCGAYA
DRGISNILVLRGDPPGDPLGDWVKHPDGVEYAEELVRLVRDMGDFHVGVASFPEGHYRAP
DLDHDTKYLVQKLRAGAEYSITQMFFDVEDYLRLRDRVVAYDREQGEKPIIPEIMPITSL
RSARRSLELSGSSLPPALEQRLTRAAGDGPDENRAAVREIGIEVATEMSERLIAEGAPCL
HFITLNFARATGEVLANLGMSASASV
>F9Y8C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ketogulonicigenium vulgare (strain WSH-001)|TrEMBL
MPRDLLAGFSIEVTPRALRGAGDLTALLPRGTTVYIAHIAGTPFDDMLWAAKTLRGAGFQ
PQPHFPARLIADRAALVDMIHRYQDAADVRRALVLGGGPRSPVGDFDRALQLIETEAFDR
AGFTHLFFAGHPEGSPDLDPSGGTQTADAALVSKRDFAQCSDAQSALVTQFVFDAQPVID
WTARIASLGVDLPVHVGLAGPAKLSALIRFGLACGVGSSLQVLNKRRGDLRHFLFPMRPD
AVAAALAAHVAAQPTSPIAALHLFPIGGIKPAAHWATGKRF
>S6K1R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri B1SMN1|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKAELRELLNLYKSAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVQTPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQS
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A3D0W8W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas bacterium|TrEMBL
MTLSVGQLEEARRALDGPLFADVAGDADVSFEFFPPKTEKMEAAMWEAVQTLAPLGPRFV
SVTYGAGGTTRDRTHATVARIARETNVPAAAHLTCVEASREEVDAVAREYWAAGVRHIVA
LRGDPPTMVEAFVPHPQGYASAAELVAGLKRLHPFEISVAAYPEAHPEATCAASDIDNLK
RKLDAGATRALTQFFFEPETFFRFRDAAAAAGIGAEIVPGILPVSNYAQTQKFAGMCGAA
IPDWMGRLFDGLDAHPAARQLVAATIAGELCRRLYAGGVRHFHFYTLNRAELSYAICHML
GLRPKAQAALAAA
>A0A6B8N3A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. THAF191c|TrEMBL
MVQLPHGESKMGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKT
LKPKFVSVTYGANSGERDRTHSIIKEIKAETGLIAAPHLTCIDASREELARIADDYWANG
IQSIVALRGDIPPGGGKPEMYASDLVKLLKERHDFDISVAAFPEVHPEAKSAQADLLNLK
RKVDAGANRAITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVK
VPSWMAKQFEGLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTL
GVRPQV
>A0A373TQA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF23-6LB|TrEMBL
MKIRDIIGQEKATLSFEVFPPKKDTDFASVEAAALGIAALRPSYMSVTYGAGGSTKGHTI
KLANEIQEKYGVPTIAHLTCVCANKDSIRTALSEMKNAGIENILALRGDIPKNYDGQVFT
DFAHASELVKLIKESGDFCVGGACYPEVHPDSANKQDDIANLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRIREAGIAVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEVAAGIQANLSDILLV
>A0A3P1XTI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter sp. OH1287|TrEMBL
MSASDLLVASAPTKTRFSFEVFPPRSNQAALALGAVIQHLAATRPEFISVTYGANGSHRE
ATLDLLKHIRKHTDVLPMAHLTTVATPREQLEAVIQGLMDAGIHDFLALRGDNPRGMDEA
DPLLQDSLSSLELINLLSAARASRPAFTSVGRTAVAVYPTGHPQSRSLEADIDWLLQKEQ
AGASLAITQLFFYAEEYLEFVAAARAGGVKLPILPGVMPVSTSQQLRKVAELAGQQAPTE
LERAMDSAGGFAPELGVEYAIKLCRELLAGGAPSLHLYTFNKHEQVTAVLRELELI
>A0A2U9Q0D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium smegmatis (strain MKD8)|TrEMBL
MVLTDFSCAPFDEWDLVRTANVLAGSCDAVLVGEHQNRPDFPPTLMGRLLLDALADTGVT
PWITLSCRDRNRVVLEQELRGLRSIGADTVMCVTGDGRGYDVRPDVTQTFDLDGPRLVAL
AASLDMVAAVPETPTAPPVNARPRRLVEKQKAGAGIAVLNHVPYPHIVARFMESGRAAGL
TIPVIAAVAVFTDTASAAVLQGLPGLELDPAVTQRVLGAADPVEAGIEAAVEEARALLSI
DGIEGVNISGSASASGGGAAIKAEVGRRVKNLCVDRTRGEAP
>M5S2K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula europaea SH398|TrEMBL
MICLMTLASVYQSTDCAISFELFPPKTSEGVDLLCKNVERLMQFGPKYFTCTYGAGGSSQ
GTTLEVLQKVKEITSLPVASHLTCVGSTVKELETYLTEARRIGVDYIVALRGDPPKGTTQ
FEVTEGGLKYANELVELIRGQFSDLGIAVAGYPETHQEAVDFQTDLTNLKRKVDAGADIV
ITQLFYDNDDFYRFRDACQKIGIEVPIVPGILPVTNFKQAKRIASMCKAAIPQSLESAMT
EAGDDQDQFRVGVEHARQQTIDLVNNGVPGIHYYVLNKSEAAADLLDGLSLTSC
>A0A842JZQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 4CII|TrEMBL
MTFDSVRGRASDGWVTRTPSIVDRIRSSGDGRVPFSVEFSPPRDEAAEARLWRAVREFER
MGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWQKHPDGVEYAEELVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLGSV
RRMLELSGSSLPAHLEKRLATAAGDGPDENRAAVREIGIDLATEMSERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSGVAAPHPVTPTPVS
>F0KJ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus (strain PHEA-2)|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKVQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A8D3Y446|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas balearica DSM 6083|TrEMBL
MSTSHRPSISFEFFPTKTDAGHEKLLATARQLAAQQPDFFSCTYGAGGSTRDRTLNTVLQ
LDSEVKVPTAPHLSCVGDSKTELRGLLNLYRDAGIRRIVALRGDLPSGMGLASGELRFAN
ELVEFIRSETGDHFHIEVAAYPEMHPQARNFEDDLSNFARKAQAGADSAITQYFFNADCY
FYFVERVRKLGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIESIQA
FGEQVIAQMCEKLLAGGAPGLHFYTLNQAEPSLAICSALGLSR
>A0A368BZ39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR86 cluster bacterium|TrEMBL
MGAPLRCRIMNISLEFFPPANLDFNALLSEYKKLEHLDPSFVSVTYGAGGGAENKSLELI
KALKKNNLDIAAHITLVNKSIDDLEKIVSDFAKLGVKKFVALRGDSPGGKFKQHPNGFFN
TSDFVEFLNNKNFEVIVSAYPEPHPDSKGFDFDLQLLKNKSESGAKKAITQFCFSKDDYE
KLIETVLKENIEVEVIPGIMPIYNIENMTRMAEKCGTKVPPNIINKFGNDDISNQKYAVE
ICNDQLDYLSELGCQKFHFYTLNKSYLINKIFRERSLL
>A0A839QEB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paeniglutamicibacter cryotolerans|TrEMBL
MTPEHPDPTSGPRRLLSGFSMEMTGKDIPELEAATPNIPPGTPINVTFLGNEDLGMRVAA
ASAVKAAGFHPVPHISARRLSSATELGEFLDALAKHGASGHVFAVGGDPATPMGPYPDAL
SLIASGVFEDFGVGTVSIAGYPDGHAEIDDRMLWAALEAKHAALAERGLGGEIITQFGFD
TTPVLDWLAELRGRGVDLPVRVGVPGPAGIKRLLGYARRFGVSSSAGIAKRYGFSLSNLL
GNAGPERFIQDLARDYDPSLHGEVQLHFYTFGGLEATADWVAGQR
>A0A3P1VH86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. OH4692_COT-348|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLNKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKHIHQATHALFNHQSLG
>A0A495U1S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. RAU2J|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLASLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHLSCIGSSKESLRAILNEYRKHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFANKVRAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCQRLIDAKVPGLHFYTLNGAAATKAICERLGA
>A0A1D7NJ59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyrobacter sp. LM 6|TrEMBL
MTPTLSQLHEYRTATDAPLFSGLPGDVAVSFEFFPPKSEKMEAQLWDAVTQLKPLGPSFV
SVTYGAGGSTRERTHATVARIIAEAKLPAAAHLTCVAASKAEIREVAEHYWEAGVRHIVA
LRGDAGEPGAPFTPHPEGYASAAELVAGLKAIAPFEISVAAYPETHPDAANRQADIDNLK
RKLDAGASRAISQFFFSADTFFRFRDECAAAGIDAPILPGILPVTNVAQARKFASACGAA
IPAWMDGLFEGLDAMPAARQLVAATVAAELCRRLYAGGVRDFHFYTLNRPELAYAICHLL
GKRPSGEAA
>A0A4V2ZB66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. GT3P67|TrEMBL
MKVTQHIEDAKEKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTIPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQYFIPKQGGNDFAVDLVKQINQLNCGKYLHDVMDVDNKANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVARAREMGITVPIIPGIK
PIAVQRHMQILPQIFRIDLPEDLIHAVDQCKTNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A4U8VBE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium PBA|TrEMBL
MQERHFSFEFFPPKTPEGAEKLRVTRSQLATLQPKFISVTFGAGGTTQQGTLDAVLEIQR
EGTEAAPHLSCVGSSRDSIRQILKTYREAGIRHIVALRGDLPSGMGEIGEFRFANELVEF
IRAETGDWFHIEVAAYPEYHPQSRSPRHDMENFARKVKAGADSAITQYFYNADAYFRFVD
DVRRLGVEIPIVPGIMPITNYSQLMRFSDMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTSLCERLLASDVPGLHFYTLNAAGPTKSLWQRLGL
>A0A011N7I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter sp. BA-92|TrEMBL
MTPNKRTFSLELFPPQTPEGAEKLRAARARMAKLKPRFFSVTFGAGGSTRERTLETVLDI
QHEGHQAAPHLSCIGSTRESIRSILEQYRANGIRHLVALRGDLPSGMARPGTFRYANELV
EFIRAQTGDWFHIEVAAYPEYHPQAKNPQEDLQNFKRKLDAGANSAITQYFYNFDAYAHF
IDDCQAAGIDAPIVPGIMPIAGYSSLARFSDTCGAEIPRWIRRKLESYGDDSASIRAFGL
DVVTRLCEQLLANGAPGLHFYTLNQDALTTALWQRLHLS
>A0A254RHN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWR2|TrEMBL
MKIVDILKQDKMSLSFEVFPPKKETSFDSVKAATESIAALGPAFMSVTYGAGGGVSQYTL
EIAKNLKQKFNIPMLAHLTCVSSSKDTVRQRIEDMKAAGIKNVMALRGDLTPELIENGRD
NCDYKHAIDLIRELKESDSDFCIGAACYPEKHPESPNQAEDIKHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVSCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPDAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFAG
>A0A7X8ZER1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp|TrEMBL
MSSMNIPASSQWSISDVLKHPVPGRVPFSVEFMPPRDDAAENRLYRAAEVFHDLGASFVS
VTYGAGGSTRERTSRVARRLSRQPLTTLVHLTLVDHTREELEEILRGYSELGLINLLALR
GDPPGDPLGDWVTTEGGFDYALDLIEMIRDNPEFAHFDLGIASFPEGHYRAGSLENDTRY
TLAKLRAGAEYSITQMFFDVDDFLRLRDRLAAADPVHGAKPIIPGLMPITSLRSVRRQVE
LSGAVLPRALEERLLKAANGDEEANKAEVRKVGIEVTSEMAERLIAEGVPDLHFMTLNFT
RATQEVLHNLGMAPAWGAEHGHDAVR
>A0A2P8MEB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. NJ4|TrEMBL
MVNTVIREYIKNNVLVTDGAMGTYYSKTTGDYNNFCEFANLTNPEVILNIHKEYIKSGAK
LIRTNTFSANTLTMDISKTELENIITKGYMIARKAAEGKEIFIAADIGPINKFEIEKPVE
YIIEEYKFVVDIFMNLGADIFVFETLSSIDCLKEVFQYIKRKNKNAFILAQFAIMQDGFT
REGISVNSIVNKIKAIGSIDAYGFNCGSGPAHLYNIIKGLDIYGDIISTLPNAGYPEIIN
ERMVYVDNPDYFADKMSMIKNRGVKIVGGCCGTTPKHIEKMVSNLKENLINIEEIEIKKN
KGINNYKKKNSFTEKLDKGEFPIVVELDPPFDTNIDKIMYAAKVCKQNNIDLVTIADSPM
SKVRVDSVMIASKIKRELGIEVMPHICCRDKNVNAIRSSLLAAHIEGIRNILAITGDPVT
GIDKVNTKSVFNLNSYKLMNLISEMNKETFKEDKISIGGALNLNVLNKEVEVTRMLKKVE
NGGTFFLTQPIFKEETIEFLAKLKKDRNIKIIGGVLPIVSYRNIQFINNELFGVDIPKEY
IERFSVDMTRQEAEEVGVNLARELIAKIRNYVDGIYIVTPFNRIGMVMKILENVRK
>A0A5J4R4N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
MKIIDLIADSKHTAFSFEILPPLKGTSISKLYDMIDTLREFNPKYINITTHRSEYVYTDI
GNGLYQQNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLIDLQFLGITDL
LVLRGDKAKHEPVFTPEENGCLHAIELQEQINNFNKGIFIDGSKAKEAITPFSYGVACYP
EKHEESPNTDY
>A0A5B0F7T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ANT_J28|TrEMBL
MSEDRRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>I9URW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides xylanisolvens CL03T12C04|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A0B5I200|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces vietnamensis|TrEMBL
MSPTFSFEFFPPKTDKGEQTLWDAIRRVEALKPDFVSVTYGAGGSSRHRTIEVTKRIVTE
TTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGDPRGEWTPHPQGFTHAH
ELVRMIRRLGDFSVGVAAFPERHPRSSDWESDIRHFVAKCRAGADYAITQMFFDPEDYLR
LRDRVAAAGCDTPIIPEIMPATDVRQISRFAELSNAAFPETLARRLDAARDNRDVAYEIG
VEHATEMSRRLLAEGAPGLHYITLNRSTAALDIHANVLGLDLKSYGETHEFAGAR
>A0A196P6Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. EhC04|TrEMBL
MATPKVSFEVFPPRTVDAAFKLWDAAQALAPLAPRFFSVTYGAGGTTRDLTHDAAHVLRR
TSGLPVAAHLTCVGASKAETMDVADSFAKIGVTDIVALRGDPADGASTFTPHPEGFQDSC
ELITALAETGKFNIRVGAYPDPHPESASQEANIEWLKRKFDAGATEAMTQFFFEAETFLR
FRDACAKAGIDKLITPGILPIVNWKSARNFAGRCGTPVPAWLDDAFAKAERDDRTSLLST
TLCTEMCSDLVDEGVENLHFYTLNRADLTRDVCRALGVTPQVTLEDVA
>A0A0D1DAU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio parahaemolyticus VP766|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDATRSELIEIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRVAVEA
>A0A071MDH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cenocepacia|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DTRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAATATRTICERLAV
>G6YEU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium amorphae CCNWGS0123|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVVREFADMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKGAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHEAEAA
GSAAA
>A0A3D9V3N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermasporomyces composti|TrEMBL
MAPRRPSTRLAAPPTVRELLAGGAVSYSFEFFPPKSDEGERQLWRTIRELEGLSPTFVSV
TYGAGGSNRDRTVRITGRIAAETTLNPVAHLTCVGHSRAELRSVVGAYADAGVRNILALR
GDPPGGPGQPWVRHPDGFDHAEELVALIRQLGDFCVGVAAFPEGHPEAESLEADARYLAR
KAKAGADFAITQFFFDADDYFALVERASRYGCDIPIIPGIMPVTNVRQIERMALLSGAEF
PADLAERLLAVEDDPAAVRAIGVEVATELCLKLLAGGAPGLHFYTLNRSTATREIYANIA
GVRAAR
>A0A8J6NL75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfolinea nitratireducens|TrEMBL
MKENRSGSTLEGLLKSGQVAVTAEVSPPDSANPEDLLKAARELAIVSDALNLTDAAGANC
HMSSIGACALLAHEGYEVVMQMTCRDRNRIALQGDLLGASAIGIKNVLCLTGDDVTIGDQ
PETKRVFDFDSIQLLHTAKTMRDESVFLSGRQISASPKLFLGAAVNPFVEPIDFRPLRLA
KKIEAGADFIQTQYCFDIKRFQDYMETVRRLGLHEKCYILVGVGPLRSELAAEFLRTKIP
GVVIPDALVNRMRKTPKKKQREEGKRICVEIIQKVLEIKGVAGIHMMAYRQEDIVGEIIE
EADLLPRPDKEMIQ
>A0A8J6NFL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfolinea nitratireducens|TrEMBL
MPIFTPGRRWQPPYLPFKKEPLNRRLLASLEKAIKGPLFGCRMCGNCLLQETAFICPMEC
PKGARNGPCGGSTEEFCYVDNTRPCMWYKIYERSFKMGREEMLLEVLPPLDWEKTGTETW
GDVTRQVKKVGTGRVVKGMLSKDAATRTVTWDSVFRPVRQPDWWEGDAKYHPPAYDEPMS
ELERRLRAGEFVVTSEVAPPVSAATGKLVRNTQMISPYVAAVNFTDCPSATPRMSSIACS
KLALENGAEPVLQIAARDRTRTGLQAEIIGASALGIRNVLCLSGDSSQMGPSPLGRSDII
DVDSVQMLWILRRMRDEGKYLDGREIKFPPQLFLGAAAAPFASEPKFQAIREHKKINAGA
QFFQTNLVYDPDGMEIWLNELAKRDILDKVYLLIGITPLKTLKMAQYMHYDVPGVFIPEK
LLKRMEAAGPDGEAEVGFEIALELIESIRNKEGVNGIHVMAVGWEDIVPRLVTEAGLLPP
DFVAPEPKADPAKVKAVA
>A0A0K9F6W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus xylanilyticus|TrEMBL
MGLLERLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLEQI
LATVDEQATVLLAGNPDGLLLETYYDFEELTATLSMLRAKTKLPIIAQVSMHEPGILQNG
MSLNNALHELEALGADIVGVNCRLGPHHTIQAFEGVELPEKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVEEKYTKPEKVEV
VREAEPANYEPLHIKVKRERSIIVELDTPRHLEIEGFIEGAKKIYEAGADVVMMADNSLA
SPRISNVAMGALLKETHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVSR
LEKKIEHGADYFISQPVYTKEKIVEIYEATKHLETPIYIGIMPVTSYKSAEFLHHEVPGI
KLSDDALSRMKACGDDREHATLEGIAIAKELVEVAAEYFNGIYLITPFLRYDMTLELMKF
IEQLDEQKKGVSING
>C0RE88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella melitensis biotype 2 (strain ATCC 23457)|TrEMBL
MGFYGLSCRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A8J7T4E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeota archaeon|TrEMBL
MKSFVDDLGKRFVITGEFEPPSGVSDSFLEKARKFKPYVDAINSTDSPLGKPHLSALVAS
YLVKKELGMEPVLQMCARDRNKVAIINDLLGASLLGVNHVLCLAGDYPKDAKPVYDLDST
RFARLVKEEMPKKYPGFEMKAGVAYNPMCKPNEPEQIVLEKKMKWADFVQTQMVFDFDLL
DNKAVQNFKEKILVGVLPLLSKGMAEYFNNNVPGVSIPPETIKSINAPEDGIKLANEITK
AAKKEGFGGAHLMVFDVEDRIPEILAGLV
>A0A5P2CAA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces venezuelae|TrEMBL
MTALRALIDQDTPSFSFEFFPPKSDAAARTLWKAIRRIETLAPTFVSVTYGAGGSSRDRT
VEVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLAVRGDPPGDPGAPWI
AHPDGFTHAHELVRLVKESGDFSVGVAAFPERHPRSTDWDSDIRHFVAKCRAGADYAITQ
MFFHVEDYLRLRDKVTAAGCTTPIIPEIMPATDVRQISRFAQLSGAAFPEHLAHRLDAAR
HHPAEGHRIGVDHATAMARRLLAEGAPGLHYITLNRSTATLEIHRNVTDARSTPHDLAAH
H
>A0A4Y8WBY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio ouci|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELIQIADDYWANGIQSIVALRGD
IPAGGGAPEMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRSVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAQQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQG
>A0A520R5F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvularculaceae bacterium|TrEMBL
MSDLQVSFEFFPPKNEAMQKKLWSSVEKLKPLEPKFVSVTYGAGGSTRERTHDTVLRIIN
ETGLSVAAHLTCVAATKDEIDDVLRAYWDAGVRHIVALRGDPPGGPGDPYTPHPGGYANA
AELAAGARKIGDFEISVGCYPEKHPDSPSTAADIDMLKRKVDAGATRGITQFFYDNTAYL
RYVERVRAAGIDIPIVPGIMPVTNFTSVRRMADVCGTTLPGRLVKLFQNLDDDPATRQLI
AATVAAEQCLDLAEHGVKHFHFYTLNRDDLAYALCHMLGLRPRGKPRVNAA
>E3DCE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia sp. (strain Ejp617)|TrEMBL
MSFFHANQREALNQSLAEISGQINVSFEFFPPRTGEMEDILWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELRTIAEDYWNNGIRHIVALRGD
LPPGGGQPEMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMTSMFA
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAPALVL
AAS
>A0A5N7TH69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKAELRELLNLYKSAGIQRIVALRGDLPSGMGIASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVQTPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A355TYQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKIANLFKENKKTVFSFEVFPPKKDSPIESVYSKMEELCALKPDFISVTYGAGGTVGHSR
TCEIASKIKYDFGVESVAHLTCVNSTKSDIDINLADLKANGIENILALRGDYVEGVEPVH
DFKYASDLCEYIDRTEEYRQFFDIGGGCYPEVHGEAENEIEDILNLKKKVDAGASHLISQ
LFFDNNAYYRFIERAKIARIDVPIEAGIMPITNKSQITRMVSMSGASLPAKFSKILQKYE
NKPEALRDAGIAYAIEQIIDLIANGVDGIHLYTMNNPYVAKKITEAVANLL
>A0A835X0I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon|TrEMBL
MTIIYEVNPPKLPKDKTLSDDERKNLLEKLNERMSEISKNCDGIHITDSVLGTKRISPLV
ASKSIKKNFPDMKMTISVRVRDNDITEIEKIVNDAITLGVNGVLILKGDASPDNTKDSGL
IPSQVVKHLKELELDKKIDLFLSLPANPDFKKIQKKIDAKPIGFITQVVESVDQVSNLVS
LLKPHGFKIIPIVLFPSDKNLKSAQFLKLDWSNYEENVFDFIKKIHDLTTNVLITSPNDF
NGVQKTLTKLVI
>A0A6G2T5C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8359|TrEMBL
MALGTASTRTDHARTVRDMLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVTYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A811T189|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella hafniensis|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAADLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPNWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A8G1N2Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycomyces sp. TRM65418|TrEMBL
MPQQAAKIGDLLRSGTPKFSFEMFPPRSEKDEQILWRTVRALEGLGADFVSVTYGAGGST
RQKTVETTERINAETTLLTMAHCTAVDHSVAELRNLIGHFANVGVRNILALRGDPPGDPR
AEWVRHPEGLHYARELVELIKHSGDFSVGVAAFPEGHPRDADWETGVRYFVEKCRAGADF
AITQIFYRVEDYLRLRDAVAAAGCDIPILPGIMPVTNIKQIERFAILTGMDFPEDLAARL
RAVEGDRDAIRDIGVEVATDMGSRLLAEGAPGLHFTTLNHSRSTRRVWQNLRR
>A0A6V8KXU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytohabitans rumicis|TrEMBL
MALGLPSVFPGSQPSIGDLIRGPAPTFSFEFFPPKTAEGERLLWQAIRELESLRPTFVSI
TYGAGGSTRDTTVALTERVATETTLLPMAHLTAVNHSVAELRHVIGRLAAVGVRNVLAVR
GDPPGNPMGEWVRHPEGVLYADELVRLVKASGDFSVGVAAFPYKHPRSADVATDTARFID
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPIVPGVMPVTKMATIERSEQLSGAPF
PPALAARFEQVADDPEAVRRLGIEQCSQMCQRLLDEGVPGIHFITLNRSTATREVWQNLP
VTARV
>A0A1V4MHX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|delta proteobacterium ML8_D|TrEMBL
MKYNFVEQLNEKVMLGDGAFGTYLFEKGVDLSKNTDSLNISDPDLVYSIHEEYIRAGSEL
IETNTFGANRFKMLKTGREHKIREINIKGAELACRAAGNDIFVAGSIGPTGVKFPFENDE
IDSSAVQDAFFEQMTALLEGGVDLFIIETFTYLDEILLAIETAKKVAPDIPIVAQMIYPF
RGRTAIGLDALDCGRATAAAGATVVGTNCGRGVKAMLSAVERLSLLKDEVLLSAFPNAGL
PEVIEHRMVYSTPPAYMAEKVAEMVKLGVRLIGGCCGTTPAHIHEFRQHLHIKRPKAIGV
TARAEKIFDLPEGEKDLVGRGGLIDGLRPDRIPVLVEVDPPKHLDIEDILTGARALADAG
ADAITLAEHPLAVLRTDNLSLAHKIRVETGIQTVLHLTCRDRNVLGLQAQIMGAHILGLE
AILAITGDPATSTDQPGVSGVFDVRSFGLIQMISQFNRGLNMAGISMKKRTNFSIGAAFS
YRPANPDLQISRLGRKADLGAHFVMTQPIFDRDAVEDMMNSTQHLNLLIFTGIFPLISAR
NADFLHNEIPGISIPRQIRKHLWKYEKVEDQRKAALDLSRKLIADIITFVDGLYLISPLN
KWEIPLKLLQELRASGH
>W5TQ15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia nova SH22a|TrEMBL
MHSGPRIPFSVEFNPPRDPAGEARLWRTVRQFERMHPAFVSMTYGAGGSTKDRTARITGE
LAQETTLLPVAHLTAVAHSVAELRALVGSYADCGIRNILVLRGDPPGDPLGEWRKHPDGV
EYAEELVRIVRGLGEFNVGVASFPQGHHRSPDLDSDTAFLAAKLAAGADYSITQMFFDVE
HYLRLRDRVLAADPEQGSKPIIPELMPITSLRTVARAEELSGRPLPEAVANRLRRAAGTG
AEPDHAAVRAAGIEIATEMAQRLIDEGAPCLHFITLNFAKATTEVLTNLGYAVSAAPHPQ
VDPLPADSPRAG
>A0A4S8P4U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium ipomoeae|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKVF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VQNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDHVIARLEGAADQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEFVAEIVHESGILKGRKPWKREHARADDIAAERMREIGADPVQDQQELAARAA
HAQQH
>A0A0R0MJA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Curvibacter sp. PAE-UM|TrEMBL
MSLQQLPLSIEFFPPKTPEGVEKLRAVRQQLKALKPEFCSVTYGAGGSTQEGTFAAVREI
LAEGMDAASHISCIGATQATMRENLVTLKAMGVKRLVTLRGDLPSGYGAGGEFQYASDLV
AFIRAETGDHFHIEVAAYPEIHPQAKSPASDLQAFVTKVKAGADSAITQYFYNADAYFRF
VEEADALGVTVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIKAFGL
DVVTELCEQLRAGGAPALHFYSMNQSVATLEICKRLGL
>A0A372BRD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. JW|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLRIVHQELQLLNPDFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKTQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A353VQ76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rikenellaceae bacterium|TrEMBL
MTMKQYPSLEIVPPLKGMTKDELLDDIRPFIEFTPKYINVTCHRDEIMYDEQPDGSYRKR
LVRRRVSETAVCGAIQSEFKVDVVPHLICGGLTAEQIEFQLQDFKFMGISNVLALRGDCL
TGEKRFSPVPGGYNHANELVEAIRCFEKENGCEGFFRIGVGGYPEKHFEAANMDEDIANL
KRKVDAGANYITTQMFFDNKVFYDFVDRCRKAGISVPIIPGLKPISTPKQVKLLPESFSI
DIPFELTSEIAAHEEDKESVYQIGQEWAMAQCKDLLAHGVPGVHFYTMGKSANIIGILRE
CF
>A0A2D0JLS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus miraniensis|TrEMBL
MSFFHANQREALNQNLAELDGQIRVSFEFFPPSTPEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKEKTGLDAAPHLTCIDASREELRDIAHDYWRNGIRHIVALRGD
LPNDSGKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATITNVRIPSWMTKMFE
GLEDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPS
>A0A3D4JXL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
LPEDLINEVENAKNNEAVKQIGIEWAIAQCRELLEFGVPVLHFYSMGKSDNIKKVAGALF
>F3PLP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides clarus YIT 12056|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESAFTPEGNGYHHAIELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTKEVLKCKNDAEAQQVGIEWCVQQCRELMEHRIPSIHF
YSIGAVDSIREVAKQIY
>A0A7Y1SJF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium|TrEMBL
MNKHDIDVERVGTNPGDPLVSLPGHVSHGRFERVLRAGNFAVTTEIAPPDSSDPDEVLKR
ASLFDGYVDAINATDGSGGNCHMSSLAVCAILTRVGYSPILQISCRDRNRISIQGDTLGA
AALGVCNVLSLTGDDVGAGDHPEAKPVFDLDSISLTKTLRVLRDESRFLSGRKLDLAPKI
FIGSTINPFVPPQHSRVNQLAKKINAGAEYIQSQYCFDIPVLKDFMKRAVDMGLTENCYI
LIGVGVLPSARTASWMRENVPGVHIPDEIINRLKSADKPLREGRNICVELMQEIKEIPGV
AGLHVMAYRQEKWVGDVVKSSGVLAGRTPWSPDHSETTIGLVS
>A0A8J5ES05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MKVVDKVRSAAEGDGRTVFSFEFFPPKTEEGVENLFERMDRMVAHNPSFCDITWGAGGST
ADVTLDIANRMQNMACVETMMHLTCTNMPVEKINHALNTIKANGIQNVLALRGDPPHGQD
KFVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDMIQGDEGALLEAYNSDLAYL
KRKVDAGADLVITQLFYDTDTFLKFVDDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPPEITAALDPIKDNEEAVRAYGIHLGTEMCKKILDHGIKTLHLYTLNMEKSALAILMV
NLGLIEESKISRSLPWRRPTNIFRSKEDVRPIFWANRPKSYISRTVGWDQYPHGRWGDSK
NPSYGALTDYQFMRPRARGKKLHEEWATPLKSVDDVNERFMKFCQGKLRSSPWSELDGLQ
PETKIIDEQLSQVNLRGFLTINSQPAINGEKSDSPAVGWGGPGGYVYQKAYLEFFCSKDK
LIAITEKCKALPSITYVAVSKEGECISNCTLNAVNAVTWGVFPGKEIIQPTVVDPASFMI
WKDEAFEIWTRGWACLFPEDDPSREVLTQVQKSYFLVSLVDNDYVHGDLFAAFKDL
>A0A7C5WZA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermocrinis ruber|TrEMBL
MKIGELLKSEFSVSFEFFPPKSPEGERELFETIKELEALKPTFVSVTYGAGGSTRDRTRR
IAYRIHTETKLTVMAHLTCIAHSKEELLEILQDYKNIGIENILALRGDMPKGDFQAPKGA
CKYAVELVRFIRENFDNFFSVGVASYPEKHPESPNMEWEIRFFKEKVLAGADFSITQMFF
DNSYYYRFVERCHKEGINIPIIPGIMPITNFSQIKKFASMCGATIPQGLVETLEPYAEDP
EETTKRGVEFAIRQCEDLIANGVPGLHFYTLNKSRATLLIYQAIKHLIPPKVLSRLF
>A0A6L6IK65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia alba|TrEMBL
MSFFHANQRDALNQSLAEVQGQINVSFEFFPPRTGEMAQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRVIARDYWNNGIRHIVALRGD
LPPDSGRPEMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGAGRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSTMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPI
>A0A7Z1GRF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas poae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLATYHPDFFSCTYGAGGSTRDRTINTVLQLE
SEVNIPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISNMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A8J5H430|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
METIMHLTCMNIPVEKIDHALNTIKANGIQNVLALKGDPPHGQDKFVQVAGGFACVLDLV
QHIRAKYGDYFGITVAGYPKAHPDMIQGDEGATLEAYNSDLAYLKRKTLSVVLKFWKSFS
HVKILELCEIFILWSAIREA
>A0A2M7Y183|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclales bacterium CG_4_9_14_3_um_filter_68_10|TrEMBL
MARTFSFEFFPPQTAEGVEKLRATRRQLAQLEPAFFSCTFGAGGSTREHTLETVLEIQAE
GLCAAPHLSCIGSTRENIAALLDRYREAGVRRIVALRGDLPSGMAAAGEFRYANELVSFI
RERTGDWFHIEVAAYPEYHPQAKSPAEDLANFKRKVEAGADSAITQYFYNADAYEHFVGE
CAAIGVDVPIVPGIMPIANFTKIARFSDACGAEIPRWMRKKFESFGDDAASVRSFGLDVV
TALCERLLAAGAPGLHFYTLNQAGLTCTIWERLGLGSRDRE
>W1TTH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus anginosus DORA_7|TrEMBL
MSIQSPSLSFEVFPPNPAVGNENIMVALKEMQDLAPHFISVTASNNKFNIEETTVRLADF
ICNGLHIPTIAHLSAVYLTKEMVTETLTVLDKIGVHKVLALRGDILRDVEPQKDFVYATD
LIEYIKKEAPHFEIIGACYLEGHPDSPDRVSNIKNLKKKVDAGCSSLVTQLFFDNERFYD
FQERCTLAGIEVPIHAGIIPILNRNQVLRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSSTAHQIYQATHTFFNNKVSS
>A0A0Q9TUU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrabacter sp. Soil810|TrEMBL
MAHGTASSMARAERFTRSIPAMIEADTPTFSFEFFPPKDDASEAQLWDAIRRLEKVSPSF
VSITYGAGGGTRDRTVRLTQRVLEATSLTPMAHLTCVGHSVAELRGIVGSYAAAGVRNIL
ALRGDPQGGLGQPWVAHPEGLDHADELVALVRGLGDFTVGVAAFPDGHPESGDIGEDAET
LVRKERAGAEFAITQMVFDVDHYLRLRDELVRRGSRLPVVPAIMPITNARQVVRMAQLAG
QPMPTAVTDRLERHGDDAAGVRAEGMAIATESSRRLLDEGAPGIHFITMNRSSATLEVFG
NL
>M6RB90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Icterohaemorrhagiae str. Verdun HP|TrEMBL
MNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEVEHRP
EEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESA
>C3MDU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium fredii (strain NBRC 101917 / NGR234)|TrEMBL
MSPDINPFDPSAPLDPLPGHSSRGRLERVLRRSEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPHVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSVITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHEATPTETLVAERLGHLREGIEENQQRMAEAAAH
HPH
>A0A366PJ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella moniliformis|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFETTLREHPSGAFEGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKKRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQSNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPTNEWDILKAKLTSPELQDSVCFYASNARGDYLSSDSSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A3B8KMG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminiclostridium sp|TrEMBL
MRLIDLFKTKKPVISFEIFPPKLDMPLDSIYDKLEDFKKLKPDFISVTYGAGGSAKDRTI
EIASKIKKDYKIESMAHFTCVGHSKEEIDSLIDSLENEGLENVLALRGDPPRDQPDFDFS
KNVYQYASQLIEHIKKRSNLCIAAAAYAEGHVDSPRIKDDLINLKNKVDTGVDFLVTQLF
FDNRIFYDFLDRAISLGITCPVTPGIMPVFRADQIKRIASLCGASIPAQLVIIMDKYGGN
PDDMLKAGIEYACMQIQDLIDNGVDGIHLLTMNRAKSTRKILENLNLLNR
>A0A2M8GHL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium CG_4_8_14_3_um_filter_49_14|TrEMBL
MTISFKETLASGKFIVTSEVGPPKGTNLEKMIHHIALLKESVAAINLTDHQSSIMRYPSL
GAALLVKEQGGEPILQMTCRDRNRLALQADLLFAYSRGIKNVLCLTGDSLVVGDHKEARG
VFDLDSSQLLAAIRTLEKGKDMGGNDLDGTVSFCAGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVYDLDKFRDFMSYARQFPVKILAGIILLTSAPMARYMNKNVPGVRVPQELID
EMAAAPKGSTLSKGIEIAGRMIREIKDDRICDGVHVMAIGKEEVVPEILKEAGL
>A0A3P1YA56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium OH2310_COT-174|TrEMBL
MSASAPSQPQAPRAALSLEFFPPKTEAGALKLRATRQALYSLQPQFCSVTYGAGGSTQAG
TFAAVREILAEGQQAAAHFSCIGATREKLRAELAELQAMGVKRLVALRGDLPSGYGLGGE
FQYASDLVAFIRTETGEHFHIEVAAYPEMHPQAASPEKDLQAFATKVRAGANSAITQYFF
NADAYFRFVDEAQRLGLDLPIVPGIMPIHAASQLLRFSDACGAEVPRWVRSRLQAYGDDT
ASIQAFGLDVVTQLCQRLLAAGAPGLHFYTMNQSTLVLEIARRLGLPTH
>A0A368Z1A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium bourgognense|TrEMBL
MTKIAASIEVAARQAIESQDLPGLFPTGTRVYITDMGTDSVDTLTAAAKRIHELGYKPVP
HFASRRLTTKAALETRIRRAAQEAGVTDVLVIGGGLERQAGEFSSTMEVLETGFFDKYGI
TEMGVAGHPEGSPEFSEAVAIEALRLKKDFGERTGAKLRVVTQFGFDADRFIRYSESLRQ
HGVDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNALSLTALATSHSPEGVVGPIE
QHVLANPTSVIKQIHIFPFGGLKKSSEWLVDRGSWSLNTAHYSTNAVAN
>A0A7H4UDE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum|TrEMBL
MNLKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHQSYIQAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVRIAVTAREHADHPVYILGTIGGLAGDTDAAVQR
ATQAEIAANVTEQLTALLATEQLDGILLETYYDLSELLAALKIVKAHTDLPVITNVSMLA
AGVLRNGTSFTDAIVQLHAAGADVIGTNCRLGPYYLAQSFENLAIPADVKLAVYPNSGLP
GTDQDGAIVYDGEPSYFEEYAERFRQLGLSIIGGCCGTTPLHTAATVRGLSSRSLVPHNA
PTHVAQAPTLVTTKSQHRFLHKVVTEKTVLVELDPPRDFDTRKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTAIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAV
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TDVSTKSISRKLSYGCDYIITQPVYDLANVDALADALAANQIDVPVFVGVMPLVSRRNAE
FLHHEVHGIRLPKSVLERMQQAELDGNERAVGITIAKELIDGICARFNGVHIVTPFNRFK
TVLELVNYVQQKNLTKVQ
>A0A7H0MJN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kosakonia sp. SMBL-WEM22|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPEMYATDLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGASRA
ITQFFFDVESYLRFRDRCASTGIDVEIVPGILPVSNFKQAKKFADMTNVRIPAWMTQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPACNVAV
>R7QW52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:182|TrEMBL
MNIAAYLKEHRLITDGAMGTYYQKKYKDEHIFVERANTEAPERVKEIHLDYIAAGAKLIR
TNTFATNTMFFDTMEEVTENIKAGYQIAEKAVAESGSEVFIAADLGPIYDSGEEAYEDVL
AEYKTICDTFFACGARIFLFETLSDFAYVSPLAAYIKEKGDTFVIAQFSFDKSGYTKSGI
SVKRVIELAAGDDAIDAYGFNCGVEAAHLYQLLKDAEFPNEKYLTALPNAGYPVVLRGKT
VYSSNERYFVEMQKKIAVLGVDILGGCCGTEPSYIEKLGQALEESPRGKKRIGQIVPEAG
EKSSHALEEKFAKKEKVYIVELDPPFQTDIAKVMNGAKLLKENQVDLITLADSPMARARM
DAGLLAEKVQREVGIPVMPHICCRDKNVLALRSTLLGDYMAGIRQFLFITGDPVAREFKG
KISSVFDFNSIKLMNYVKEMNADVFAEDPVCYSGALNYHGVNVDAIIKRMQLKIAEGCTF
FLTQPIYTDADGGRIRYVERIRYIKEHVDTRLICGIMPLVSYKNALFVCNEMPGIHITRD
IVDRYDKEMTREEAEAVATQISVETAKKLYDMADGFYMMTPFNRAGLISNIITEIRKIGE
R
>A0A6G7W5Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia terrae|TrEMBL
MRPAPYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFFPPRDAEAESRLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSVAELRALVGAYADQGIT
NILALRGDPPGDPLGEWVAHPDGVEYAEQLVRLIDTLGDFHVGVASFPETHHRSPDIEHD
TRTLVSKLRAGAEYSITQMFFDVEHYLRLRDRVAAADPEQGLKPIIPGIMPVTSLATVRR
MVELSGSVIPPDVEERFAKAAGNGAEEDRASVRAVGIDFATEMAQRLVAEGAPCLHFCSL
NFAKATTEVLGRLGVDVDAALHVPA
>A0A7X3DG70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Z38|TrEMBL
MTTFSFEFFPPKTAAGERTLWQAIRQVEPLRPDFVSVTYGAGGSSRASTIEVTRRIAAET
TLRPVAHLTAVGHSVTELRQIIGAYADAGIKDVLVLRGDPPGDPRGPWAAHPDGFTHAYQ
LVELVRSLGDFTIGVAAFPERHPRSPDWDTDIRHFVAKCRAGADYAITQMFFHVEDYLRL
RDRVAAAGCDIPIVPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAARDDRAAGHRIGV
EYATAMAERLLTEGAPGLHYITLNRSTAALDIHRNVISSRSIRVA
>A0A4R3M2B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paralcaligenes ureilyticus|TrEMBL
MNSASSISLEFFPPRDIAAQEKLVRSAKQLLALHPSYVSVTFGAGGSTRSGTADTVSLMQ
NLGCEAAPHLSCIGSSRAVLTEILDAYRAAGIRRIVALRGDTPSGMGVEAGELRYASDLV
RFIREHSGDWFHIEVAAYPEMHPQALNASEDLDHFVTKVKAGANSAITQYFFNADAYSDF
VNRVRAKGVSIPIVPGIMPITNHSQLVRFSTMCGAEIPRWIRLRLAEFGDDRASIKAFGA
DVITRLCQRLLDQGAPGLHFYTLNNADSILAIHRGLS
>A0A2N3FIV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium HGW-Actinobacteria-6|TrEMBL
MGRQVRGASRPRLHARPHPAPPHRTRPGWSEAASSQGLLQEAQARLGQHPQVQERRCRVS
RLRDALERGEFVVTGEIAPPLGTDLSAMRRSIETIGPYCHAINITDNQGASLHLSSLAAS
RVALDMGFEPIFQQTCRDRNRLALQSDLLAAWTLGLENVLIVTGDDPRSGDHPEAKGVFD
LDSTQLLEVASAMNAGSDMIGRPLKGGTDFYLGAAMFPEAEPWDIQMIRATRKVEAGASF
FQTQAIFDITKLERAVEVMRPLGVKVIAGVLVLRSGRAVDFINERLAGLMVPEEIGARIK
GADNAASEAVALATEQVRAAREVADGVHIMTLGLDDAVPEILRGAGIS
>A0A2L0N899|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB01881|TrEMBL
MALGIASTRTDRALTVRELLAAGKRSFSFEFMPPRTEVGEQRLWDAIRRLEPLDPNFVCM
TYGAGGSSRERTVNMVGRIATETTLTPVAHLTAVDHSVAELRNIIGQYADQGVRNVLAVR
GDPPGDPMGEWVKHPQGVTYAYELVELIKGIGDFCVGVAASPNMHPRSTDWDEDIRHFVA
KIRSGADYAITQMFFEVDDYLRLRDRVAAAGCETPIIPEIMPVTNAKQLDRFPQLSGSAF
PAELEARLRAAIDDPAALREVGMEHATAMSERLLAEGAPGLHFITLNHSTATLEIYQNLG
LHQR
>A0A0P9JFS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. berberidis|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A2S6MXM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopila globiformis|TrEMBL
MDTSLDTASPTLQRWLTGPRFSGLPMRNADLPAPKLSFEFFPPRTEALEQQLWACIKRLE
PLAPRFVSVTYGAGGSTQARTHAIVSRIARETGLVPAAHLTCVGATRVDVDAVARRYWEA
GIRHIVALRGDPPPGSAYEPHPGGYPYAVDLVAGLKMVADFEISVAAYPEVHPAASSPMA
DLENLKRKLDAGATRAITQYFFETSTYLRFLDLCLAAGITAPIVPGIMPVSNFAQAVKFS
DMCGASVPAWMGRLFEGTDDDPETRRMVGMVIAAEQVRLLQANGVDEFHFYTLNRPDLTY
AIAHVLGVRARVAA
>A0A101NSV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cellostaticus|TrEMBL
MTGKDIPKLEEARDSIPRGTRINVTFLAGEDLAVRLAAARAVKRLGFVPVPHISARRLPS
QAHLEEFLAGLAADGTAENVFVVGGDPARPEGPYEDALSVIRTGLLQRYGARHIGISGYP
DGHPAITDRTLWSALTDKTAALGTERLRGDVITQFGFDVAPVLGWLEAARARGVHLPVRI
GVPGPAGVRRLLGYAARFGVATSASVARKYGFSLTNLMGTTGPDRFLHALAKEYDPARHG
AVKVHFYTFGGLRATSEWIARFRQGDHQR
>A0A1Z8WV82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium TMED69|TrEMBL
MLISKPSETKSISFEFFPPNSAEALEKLVLEAQKFLIFQPEFFSVTFGAGGGTRKKTLLT
ANSLNQKFKISIAPHISCISLNADLARRTISQYIEAGHQRLVVLRGDMPSGVPVNSEFRY
AKDLVKFISNEFKESIFIDVAAYPECHPESLNFFDDLKYFKEKVEAGANRAITQYFFNCD
SYYRFIDDCNKLNISIPILAGLMPISNGEGILRFSKKCNADIPKWLRNKIEYYSDNNDYL
IKLGIEFMSKMCESLLENEAPGFHFYTLNKSYPTIEICKNLNFDNC
>C0WHC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium accolens ATCC 49725|TrEMBL
MSEEELMVPERLALSFEVIPPRHDADEAKIDRLLETLESYHPDYIAVTSSKRSGWLEGTT
AFIERISRTTSMRPLAHLACTAGSRTELIGWTNRLVDAGVRGLLALRGDLPEEGLPEYYP
QHADELISLIRQLERQQAARFAAGRLAVGVACYPSGHVESKNEDEDFDVLLKKQRLGADF
AITQLFFDAQDYLRFTKKAQLVGVHIPLIPGIMPMTSLRRVERMGELSGLAVPERVRSAL
AAATTPEEEYETGMELTAQLARDIVAGGASGLHIYTHNNPDNTHDLLTRIGVDNDQR
>A0A1H1V302|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopseudomonas litoralis|TrEMBL
MTTNKDIPVSFEFFPTKTEAGHEKLIAAAHVLAEQQPEFFSVTYGAGGSTRDRTINTVLQ
LDQQVKIPTAPHLSCVGDSNEDLRQLLNEYREAGIRRIVALRGDLPSGMGRASGELRYAN
ELVEFIRAETGDHFIIEVAAYPEAHPQARNFEADLENFIRKVQSGADSAITQYFFNADCY
FHFVDRVRKAGVETPIVPGIMPITNYTSLSRFSDACGAEIPRWIRKQLESYGDDTASISA
FGTEVISRMCERLLAGGAPSLHFYTLNQAQPSLAILRNL
>S9QW56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubellimicrobium thermophilum DSM 16684|TrEMBL
MSLLPFLRRKSESAAAPGGAVPAFLSGWSIEVMPRTAEKVEDFRAILPPGTRVYIAHIDG
TETEDMVRTAARIAREGFPVMPHVPARSIPSREALFDLVARYRGEAGVDQALLLAGGRRE
PLGDFHSSMQLLESGAFDGFRRLHVAGHPEGNRDIDPDGSDRMVMEALRWKAAFAERTDA
AMAITTQFAFEAAPVIAWAERLKREGVGLPIHLGIAGPAKLQTLIKYAIACGVGPSLQVL
QKRAMDVTKLLLPYEPDEIVEAVAAHKAANPDFGIAQLHIFPLGGIKAAADWANKRTGTT
LAPAING
>A0A8H2ZUD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sclerotinia trifoliorum|TrEMBL
MHIKDMLAEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHYIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVTIPVIPGIMPINTYASFLRRCNHMGCKIPPKWSVAL
EAVKNDDAAVRNIGKDLVAEMCRRIIQAGVHHLHFYTMNLAQATRMVLEELNLTPSTQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLGNGIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHDP
DLTYYAVKKTGDLQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLEEPFETSENGD
VDGVRFIEPQSVPLTNGQANGH
>A0A7W6BK47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium jiangsuense|TrEMBL
MSIPVIHPNWDRPPAGITDGYSLEITAKDVESLREAAPMIAPETPIAVTFLPGEEAPARI
AATKAVRELGFEPMPHFSARRIRSHEEFQSYLSAVVNEAGVRRCFVIAGDPEQPEGPFED
SSALIATGAFERAGIRAIGIGGHPEGHPNMTEAQCWEVLERKCADIAARGMAPLIVTQFG
FDTDRFLAWLRELRARGIEHPVRIGVPGPAGIKTLLRFAARCGVGASASVMAKYGISLTR
LIGTAGPDKLVDRLATDFGSEHGRVRLHFYPFGGLVRTVEWINDYAARH
>A0A134A0U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemella haemolysans|TrEMBL
MRNLLERLEQNVLVADGAMGTALYSNGLESCHEYNNISNPDSVEKIHKAYIEAGADIIQT
NTYAAKKCQLKTYGYEDKFEEINIRAAEIARKAAGENTFVFGTIGAIRGLRECELSLETI
VNETLDQVKVLLSTNKIDALLFETYYDQEEIRAVLTEARKLTDLPIITNISLLEAGITQN
GEKVTDALSTLVNLGADIVGLNCHLGPYHMIKSLKQVPLFAQSYLSAYPNASLLQLTQTI
NGNEYRFRKNSAYFEQSAKLLVEEGVRLIGGCCGTTPEHIRAIKKGIKDLKPVKRKIITP
LPAEEELVRVANNKPTIVDKVKKQVTIIAELDPPKHLNVDKFIEGAKAIDKKNIEAITLA
DNSLASTRICNLAAATLLKEHISTPTLLHLTCRDHNLIGLQSRLMGFDILGINNVLALTG
DPSKLGDFPGATSVYDMTSLKLIPFIKQLNEGLGYNGASLKKTTNFTVAAAYNPNVRDLS
KTKRLVEKKIKAGTDYFITQPVFEAEKIEQLAEFAADYPDTPFFVGIMPITSYNNAVFLH
NEVPGIKLSEEFLAKLEEVKDDKELCQKIALEESKKLLDIALKHFKGIYLITPFFRYDLT
LELIDYVEENKDK
>A0A6S7B170|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter kerstersii|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LGNLGCDAAPHLSCVGATRQELRDILQTYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQATNPSADLDHFVAKVNAGADAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPLAVWKELAK
>A0A6I4THX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania aquimaris|TrEMBL
MREAQRALETPLFSGLAGDIEVSFEFFPPKSDKMAQTLWDSVETLAPLSPRFVSVTYGAG
GSTRERTHAAVRRIVTETSMPAAAHLTCVNATREEVDAVAREYWEEGVRHIVALRGDPPE
GGTAYKPHPGGYANAVELIAGLKRVADFEISVAAYPEVHPDSPDRQADLDNLKRKFDAGA
TRAITQFFFEPECFFDFRDKAVAAGIEGEIVPGIMPVLSFGAVQRMSGLCGTGIPDWMEG
LFAGLDEKPDARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKA
>A0A7C4RQD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatirhabdium butyrativorans|TrEMBL
MKTESVLEQVLRSGNFAVTSECGPPRGAVPAKILEKAKMLGDFVDAVNVTDNQTAMVRMS
SFAASVFLRQAGLHPILQMVTRDRNRLAMQADIIGAYSHGINTMLCLSGDHPKFGDHPMA
AAVHDIDSIQFIQMVRKMRDEGKFQGGADIENPPKMFIGAAANPFADPFELRVARLAKKV
AAGVDFIQTQCIFNLDKFELWMEGVRKRKLHEKCYILAGVTPIKTVGMARYMKNKVPGMD
VPQHIVDRMAATPKEKQADEGITICVEMIQRLRQIEGVAGIHLMAIEWEHKVPEIVQKAG
LYPRPNIQ
>A0A737Y5S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 30:1,z28:z6|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1M5W157|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium grantii DSM 8605|TrEMBL
MIKEYLKKNILVTDGAMGTYYAETTKDYLTLCELANITNPAIIEKIHQDYLKAGAKLIRS
NTFSANSISLEVSREKVKEVIEQGYKIAKSATKNSTAFIGASIGPIPKNEVDISDLHILD
EYKFIVDTFLNLGTEIFVFETFSSLEYLKEISKYIKEKNPNVFILTQFAIRLNGLSRKGI
SIKSFVEEVKSITYIDAYGFNCGSGPAHLYKHLKKLDIFSDIVSVLPNAGYPELVNERTV
YVNNPEYFSEVMFDVKKLGAKIIGGCCGTTPSHIKKLTESLNKNIVADLDSFEDDLIKTS
SITKKNNAFLKKLENKEFVIAVELDPPYDTSIEKIMLGAKVCKKNNVDLVTIADSPRAIS
RVDSIMISSKIKREIGIDTMPHICCRDKNINGLRSGLLATHIENIRNVLAVTGDPVADVD
KHSTKSVFNLNSIKLMNLISDMNKSVFEEDNITVSGALNLNVVNKDAEVSRMLKKNRNGG
YFLSYTAYL
>A0A652K2J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. adm13(2018)|TrEMBL
MSPVPGDPTFSFEFFPPKTDRGERALWEAIRRVEALAPDFVSVTYGAGGSSRDRTIGVTK
RIAAETTLRPVAHLTAIGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRGPWTPHPHG
FTYAHELVELVRSLGDFRIGVAAFPEGHPRSAGPAEDLAHFVAKCRAGADYAITQMFFDP
EDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAARDDPAA
AYRVGVDHATRMGLRLLDEGAPGLHHITLNRSTAALEIHRTILSARSVVHV
>A0A494YY40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus endophyticus|TrEMBL
MGLLEALKSKVLTADGAMGTLLYSYGLEHCHEEMNLVKPELIEKIHSEYILAGADVIQTN
TYGANAIKLARYGLESKVVEINEAAAKLAKKAASSGNQFVIGSIGGIRGVRKSEVTLDEI
LDAIRVQAETLIRADLDGLLLETYFDFEELTKTLKMLRNMTDLPIIAQVSMHEPGVLQNG
LKLNDALQQLESLGADVVGVNCRLGPHHTIQALEGVELPQNAFLSAYPNASLLDIEEGRV
IYESEIDYFARAAVQLRNQGVRLIGGCCGTTPKHIEAVKKQLAQLKPLTEKRTVQQPEIY
IQDAEPTRVEPLHEKVKRERSVIVELDTPRHLEIDSFVEGAKALYNEGADIIMMADNSLA
SPRISNVAMGSILKLQHGIRVMPHLTCRDRNLIGLQSHLMGLSALGMNDILAITGDPTKI
GDFPGATSVYDVSSMELISLIKQLNEGISFSGKALRKKANFSVAAAFNPNVRVLDRAVSR
LEKKIEHGADYFISQPVYSAEKIVEIYEATKHLEAPIYIGIMTLTSFRSAEFLHHEVPGI
KLSDEVLARMKACEGDKEREAQEGVAIAKELLDTATKYFNGIYLITPFLRYDLTLQLMQY
IKQLDEQNEGVEANA
>A0A6P2CHL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus rhodnii|TrEMBL
MLDDVIFDTVRGRASAGWRTTTPSIVDRLRGGDDTRIPFSVEFSPPRDEAAEQRLWRAVR
VFERLGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVDHSIDELRSMVGAY
ADRGISNILVLRGDPPGDPLGEWRRHPEGVEYAHELVRLVRDLGDFHVGVASFPEGHHRS
PDLDHDTRYLTAKLRAGAEYSITQVFFDVEDYLRLRDRVAAFDPEQGAKPIVPEIMPITS
LRSVRRMMELSGSRLPRHLEERLVRAAGSGPEEDRAAVRAEGIDIATEMCERLVDEGAPG
LHFITLNFARATGEVLERLGGRIRTAADSAPVRSVG
>I2NK92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus paraphrohaemolyticus HK411|TrEMBL
MSFATDIDHLNQNIADLNGKINVSFEFFPPKNEKMENLLWDSISRLAPLKPKFVSVTYGA
NSGERDRTHSIVKSIQQETGIVAAPHLTGIDATPDELRQIAKDYWDNGIRNIVALRGDEP
EGYAKKPFYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRAIS
QFFFDIDSYLRFRDRCVNVGIDVEIVPGILPVTNFKQLQKMAKITNVKIPSWMHRMYDGL
DDDPTTRNLVAASIAMDMVRVLSKEGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A0R1W839|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus nantensis DSM 16982|TrEMBL
MTETNKTPTLSFEVFPPNSEVGTANLTATLDQLEGLNPSFISVTASNHKLDYEKTTIDLA
KYVHDKLQCPTMVHMPAAYVTKKEVDEVLNRLEEMHINQVLALRGDIVEGYTPETDFKYA
SDLITYIKQQKPYFEVSGACYPEVHPDSKNRIDDIRHLKDKVDSGCDQLITQLFYDNEAF
YRFQEECAIANINVPILAGIMPIVNRKQALHVIENCSARLPKKFINILDKYKDNPVSLKE
AGIAYAVDQIVDLVTNNVEGVHLYTMNKSDTAKHIFSNTASLFGLE
>A0A2A4FS30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizorhabdus dicambivorans|TrEMBL
MTSVPLNQLEEARRALDAPLFADLAGDAAVSFEFFPPKSEKMEETLWSAIQTLAPLKPRF
VSVTYGAGGSTRERTHHTVARIASETAIPAAAHLTCVEATKAEIEEIAREYWAAGVRHIV
ALRGDPPTEGASFAPHPDGYRNAAELVAGLKAIHPFEISVAAYPECHPEAASFDSDLANL
KAKFDAGATRAITQFFFTPEAYFRFCDKARAAGITGEIVPGILPVSNVAQTRKFAGMCGA
AIPAWMDRLFEGLDDHPATRQLVAATITAEMCRRLYAGGVRQFHFYTLNRAELAFAICHL
LGLRAEAKALENAA
>R6DWY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:563|TrEMBL
MKITNILNNGKMSLSFEVFPPKTDTAFESVLHATHEIAKLKPSYMSITYGAGGGTSRYTL
DIAEDIMKDYGVPTLAHLTCVSSSKATVHERIAEMNKRGIKNVLALRGDIPAEMENEDRS
GWDHQFAVDLIREIKESGFDFCIGGACYPEIHPESPNQKEDIKHLKEKIEAGCEFLTTQM
FFDNNLLYNFLYKIREAGITVPIVAGIMPITNAKQVDRAIKLSGSFMPQRFKSLVDKFGS
DPLAMKQAGIAYATDQIIDLYANGVENVHVYSMNKPDVAQKIQSNLSDILGK
>A0A2G5L6S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reichenbachiella sp. 5M10|TrEMBL
MLNNKIEQNKSGYLFYGLTPPKDNTDEEKIHAIASRQIERLKNINLDALVLYDIQDESAR
TDVPRPFPFMQTLDPGAYSARYLQDLDVPKIIYKSVGKFTQAGFQEWLATNPNQIEYSVF
VGSPSTGQEGLSLNDAYEIKESADSKLIIGGVTIPERHFKKQDEHLRVVRKIENGCRFFI
SQCVYSLDNAKDFLSDYYYHCQDTNTPLAPIIFTLTPCGSVKTLQFMEWLGIYIPKWLKN
DLERSEDILSRSLDICKIVAKELLEFSRVKNIPIGFNIESVAIRKAEIDASIDLLREVDM
MQRASALKNELLTNKS
>A0A2N0KQZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Ae2-Chloro-G2|TrEMBL
LQGILLGAQLIGLDNVVSVMGDEFNSSEKLSQKTISDFTASGFVSSIKQMNTRVDFRDRF
LQYPTGFCVGATIDLSRDWSGEIPLTEKKVTAGADFFLSQPIFDTSQPHKFMERYFKDTG
CRLEIPVMWGVQVKVQDSVSLTPVPDWLQKDLERGRSGFEIALQIISEHTDYGFDTFYLV
PPILRGGMRDYESAQAVIDEL
>W9IMJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum NRRL 32931|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>B6JJE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afipia carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5)|TrEMBL
MSDTNSPAPSQAHRPSISFEFFPPKTEEMEQNLWGVINRLAPLAPDFVSVTYGAGGSTRE
RTHSTIKRILDETRLVPAAHLTCVDATRADVDEVVDRYHEIGVRHIVALRGDPSGGIGTS
YQAHPQGYQSSADLVSAIRSRHPEMEVTVSAYPEKHPESASLDADIDALKAKVDAGATRA
ITQFFFDNDLYFRYLDRVRAAGIAIPIVPGILPVQNFKLAKNFATRAGATVPDWLAEKFE
GLDDDADTRRLVAATVAAGQVQKLAKHGVEHFHFYTMNRADLVFAISHILGIRPNGTQKA
A
>A0A024TPG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces invadans|TrEMBL
MKIIDKINDKIEKKEAFYSFEFFPPKTPAGVTNLYSRMDRMALLEPLYCDMTWGAGGSTA
NKTIELSANAQKLSGLEMLMHLTCTNMPKGSIKNALDSAKDAGIQNILALRGDPPRGQTE
FKECEGGFSFAIDLVKYIREEYGDYFCIAVAGYPEGHSDADDLDTDILHLKEKVDAGADF
VVTQLFYDVKNYLKFVDKCRAVGVTVPIVPGIMPIQNYNGFVRMSTMCSHVPEEILQALE
PIKDNDEAVKEYGVQLGIHMCKELLAQGVPGLHIYTLNLERSTRLILEGLGLTATARREL
PWRPSTLAKRAGESVRPIFWANRPKSYLDRTANWDEFPNGRWGSSESPAFGELNESYYLH
ATASVQERKAMWGENPVTYEDVYETFTRYVMGAVKSLPWCDTPLHLETKSIQERLAAVNR
AGYLTINSQPRVNAAPSDDPMFGWGGPGGHVYQKAYVECFVSPENLKRIIEKCNKMKHVQ
YHAVDVHGNSYSNCGKGTTAVTWGSFPNKEILQPTIVDTDSFMAWKDEAFSLWLSMWASL
YNDESPAHALIHQIRDTFFLVSIVDNNFVNGNIWDAFDVDVTTSSASAAGA
>A0A329U899|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MDDIRAFLSRKPLLFDGGMGTYYKAAPGTDCEQANLTDPAGVRKVHAEYLAAGADAIKTN
TFSLPRLAAGHVPGWEKLADAGWKLAAEAAAETGAAVFADLGPAPDTEAVPAAQVYTAVA
ERFAALGAKNFLFETLSSDVGILEAVRAVKAQVPEAFVLVSFAVLPDGYTREGVYCKDLV
RRMTESGCVDAVGLNCVSAPGAMRTLARGLAGGALPLSVMPNAGYPVVTRTQVRYQGKPE
YFARELSGMAAEGAVRILGGCCGTTPAHIAALRAALDALPERKLSAEPAKLSTTEVKPVE
NDDAFLRKLNAGEKVIAIELDSPRNADLTGYLEGARKLQAAGADLLTIADCPIAQARMDS
SLVACRVHRELGMCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEV
KNVYQFNSRKLAQYIVSLAGEDREMPTPMTVFGALNLNARNFDVELRRAGEKLENGMSGF
LTQPVLSEQAVENLRRTRETLGSRAKILAGIMPVVSQRNAIFMENEINGIHVDEEIIQKF
AGLDRTGGEELGLAISLEMARKALPYADGFYLMTPFNRVALMERLIAQLRTEVLQES
>Q9I687|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A024UV54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces invadans|TrEMBL
MGKIIDRLMELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPRDQLREILKNVRAAGIRNILALRGDPPIGSE
RWKPVPGGFHNAVELIRFIREEHGDWFCIAAAGYSEVHSEAWNNPNLPPSDQARQLDMIR
LKEKQDAGADFIITQFFFDVDKLLQWIRDCRQLGISIPILPGYLPIQTHNSFLKFTNWCK
TSVPPQVQEALVSIKNDDAAVKKYGIQLAVDTCKKLIANKLSLHFYTMNLARTVRAVLEG
LHLIERERGLPWGAPIMRNKDGSLEKSIEQVRPIFWSNRASSYIARTSEWDDFPNGRWGD
RTSPAYGELSEYYLAYKRPKVARDQLWGRPQTEEDVWNVFVKFIEGSVKQLPWCEQGLSG
ESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPRLM
QRLVVALADYPNLSYHAFSANGTEYTNSPGPSVTAVTWGVFPGKEIIQPTVVDTASFAAW
KDEAFELWLSQWASAYEPETVSHQLIKRIYDSYVLVNVVDNDYTNEDSDIFKIFAQVITE
SMTKDDLRQRVLELEGKNEKLHETVAKLKIIQAEANRELKDLHGDLSSSREENSRLKAQL
RDLRSRLAMAEL
>A0A024TPF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces invadans|TrEMBL
MKIIDKINDKIEKKEAFYSFEFFPPKTPAGVTNLYSRMDRMALLEPLYCDMTWGAGGSTA
NKTIELSANAQKLSGLEMLMHLTCTNMPKGSIKNALDSAKDAGIQNILALRGDPPRGQTE
FKECEGGFSYAIDLVKYIREEYGDYFCIAVAGYPEGHSDADDLDTDILHLKEKVDAGADF
VVTQLFYDVKNYLKFVDKCRAVGVTVPIVPGIMPIQNCNGFVRMSTMCSHVPEEILQALE
PIKDNDEAVKEYGVQLGIHMCKELLAQGVPGLHMYTLNLERSTRLILEGLGLTATARREL
PWRPSTLAKRAGESVRPIFWANRPKSYLDRTANWDEFPNGRWGSSESPAFGELNESYYLH
ATASVQERKAMWGENPVTYEDVYETFTRYVMGAVKSLPWCDTPLHLETKSIQERLAAVNR
AGYLTINSQPRVNAAPSDDPMFGWGGPGGHVYQKAYVECFVSPENLKRIIEKCNKMKHVQ
YHAVDVHGNSYSNCGKGTTAVTWGSFPNKEILQPTIVDTDSFMAWKDEAFSLWLSMWASL
YNDESPAHALIHQIRDTFFLVSIVDNNFVNGNIWDAFDVDVTTSSASAAGA
>A0A852BVC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramphastos sulfuratus|TrEMBL
MVNETQHTCGASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTRDDITRHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEEDLKYLKEKVFAGADFIITQLFFRSETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTSYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7Z1LGN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hodgkinia cicadicola|TrEMBL
MINQTSVSFVAANSIYVRFSVEYLPPRKISNLSKMLTSNLNPNQTKLLEFNSITYNSENK
NRLNPTTLLLILLRRLCNCSIILHNFLTQIKCMLISDTSMLHDLGVNNILLISGDKYTTN
KKRSDDISPYRIRRLLREKHIFNIGTDYPNNHILYSGSFQDLFTMLLNRESGCSMHITQI
FNHMDNFLRNNLRCSIFKLGSLLPGLFISSKHPLAVDINLKYGIYLTRQVKELLESEYLD
ERAAFLFNMYRIIEIIKNDITWIQVFTLNKTRILKEIIWVLNDLTYYIRYWRLRTRNECY
AVMCDMHNAYKRR
>J8B163|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus BAG6X1-2|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINRAAVKLAKESVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIAGMKRVIANITPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVIVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2A6ZDK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MKDVREILKKRPLLFDGGMGTYYKAKPGQECEQANLLDPDGILTVHRAYLEAGADAIKTN
TFGLPRMAAAQNPMWEAMADEGWKLAAQAAAKTGAAVFADLGPAPDTEALPAAQIYTALA
ERFAALGAKNFLFETLSSDAGVAEAARQIKEAVPDAFVLVSFAVLPDGYTREGRHCAELV
RSMTACGAVDAVGLNCVSAPGAMRTLVQQLGRTELPLSVMPNAGYPVVTRTRVQYQGRPE
YFARELARLAAEGVRILGGCCGTTPAHIAALRTALDALPGQLPVAAAAPVPTAAKPKVET
DDAFLRKLNAGKKVIAIELDSPKDADLTGYLDGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGLNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPLTVFGALNLNARNFDVELRRAQEKLQNGMSGFL
TQPVLSAQAVVNLKKTRETLGEKAKILAGIMPVVSQRNAIFMENEVNGIHVDAEIIERFA
GLDRAQGEELGLEVSVKAAQAAAPYADGFYLMTPFNRIALMERLIARLKDEGIAD
>A0A8D3E658|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scophthalmus maximus|TrEMBL
PAGEAPRGEGSWSDSSGASNSGGESSKESSRSSTPVLDADRSDRLRDKMRRRMESADRWF
SLEFFPPRTTSGAVNLLSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYC
GLESVLHLTCCNQTREIITGHLAKAKHLGLKNIMALRGDPVGADWEEEDGGFNYAIDLVK
HIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVITQLFFRSDTFLKFL
DDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITNVIEPIKDNDAAIRNYGIH
QAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVE
DVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLHM
WGEELMKEESVFEVFTCYITAQPNCSGQKVMCLPWNDEPLAPETNLMKDELEKVNRRGVL
TINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHI
VNVHGRNLTNALDFQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYE
DESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIEDMFEMLDAPPEPV
>A0A416C1C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF37-5AT|TrEMBL
MNLREYLKETNLITDGAFGTYFAAKYQTQEIPELANLSDPEKVKKIHEEYLNAGANFIRT
NTFAANTETLQERFPEVEKNIRAAVEIARSAADGKNVWIAGDIGPIPVNGTEDAAAAADE
YYQIAKTFAETGVKVLDFETFADLDGILPAIKKIRAEYDMFIAVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPVYFAEKMKELQELGADILGGCCGTDPEFIREMSARDGILKKSAPEKEAESSGQSEP
VVRHGFLYDENGNRKEKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMANKVRQATGLNVMPHICCRDRNAIAMRSLFLGAAINDIYNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFANNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTEEDAARLRRIKDETGARILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKASRKEGEAVGIQLAKEVMKLVEDFADGYYFSFPFNRVYMLKDICNCSVGLRTCCAD
RNKTQA
>A0A1S7DPR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Riemerella anatipestifer|TrEMBL
MKVTEHIKKSEGKTLFSFEILPPLKGQNIKCIFDAIDPLIEFNPSFIDVTYHREEYEYVE
VRDGLLEKRVVRKRPGTVGICAAIQNKYKVDAIPHILCGGFNREDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKNGNAYASDLVKQIQEMNQGIYLDTSLEKAAPTNFSIGVAGY
PEKHMEAASFSQDIGHLKKKVEAGADYIITQMFFDNQKYFDFVDRCRSEGIEVPIIPGLK
PIATKSQLSLIPHRFKVDLPDDLVTAITKANNNTEAKEIGVEWCIEQSKDLMKNGVPILH
YYSMGKSESVRKIAEAIF
>A0A3E2NAK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium indicum|TrEMBL
MKITDILSQGQPTLSFEVFPPKTEDKYDSVEKAAAEIAKLHPAFMSVTYGAGGGTSKYTV
DIASALHHEYHVTALAHLTCVSSTKEKVRQVLGELKDAGIENVLALRGDIPPDAPDKREY
NYASELIREIKETGDFCIGAACYPEGHVESANKTIDMDYLKQKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVVAGIMPVTNVKQIIRSCQLSGTYLPTRFKAIVDRFGENPAAM
KQAGIAYATEQIIDLIANGVNAIHVYSMNKPDVALKIKENLSEIL
>A0A1F6SCV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Melainabacteria bacterium RIFOXYA12_FULL_32_12|TrEMBL
MKLKEIYNSKKPVISYEIFPPKGEGAELKVKIETLFQELNTLLKYNPSFISVTYGAGGST
RERTLELVLKVKNELNIQPLLHFTCVGTEKEQTHQYIKEVQDAGIENILALRGDPPKGET
KFVKPENGFGYANELVEFISFHTDLGIAVAGYPEGHQECASFEQDIINLKKKVDAGADVI
ITQLFYDNAFFFNYLEKAHKAKIDVPIIPGIMIITNVSQVERMTTMCGCTIPDKIMSKLK
EYQDDNKAVSEIGIEYAINQCKELLASDVPGLHFCTLNKASATDRVLKELDIK
>B4EZN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus mirabilis (strain HI4320)|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTQEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHAIIKDIKERTGLEAAPHLTCIDACREELQHIAQDYWQSGIRHIVALRGD
LPDNSQKPDMYAVDLVRLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKKKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMFD
GLDNDPETRALVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPQLAKV
>A6Q7Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp. (strain NBC37-1)|TrEMBL
MFEKFCDILCGDKNFITVEVNPPHGASLDKILEDIKKYKLHEKVTGFSCTDNPLAKLKMS
GVLSAIRLQQTFKKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKFSDQPE
VKGVLERDSTLLLSIIYHLNNGVDYSNKPLNPAPKPIYPFAVSNSYARNMRSLQKRIVKK
LDYGARAIITQPVYDLENAMELLELFEEAKTMSVRETSKEAHLILGQFPIVRARTANFID
DKVPGISVPKDIIDEMNLAAMDGEEKEQEVGFTLSKKIFDEMMKKHGKVHMMTHNRFDLC
SELIG
>A0A1Z1NU02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas salmonicida|TrEMBL
MGFHSARQVEALNQSLADLSGDIGVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKNPA
>K7AAW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraglaciecola psychrophila 170|TrEMBL
MASYAQGIDALNQSLSEVKGIDVSFEFFPPKTESMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQAETGIQAVPHLTCVDATREELIEIAKDYWQSGIRKIVALRGDLP
EGVEKPQSYASDLVALLKEVADFEIAVAAYPEKHPEAPNSQFDLLNLKRKADAGATEAIS
QFFFDAEVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLQRFAGFTNVHVPQWLHKMYDGL
DKDDQTTRNLMGANIAMDMVKVLAKEGVRKFHFYTLNRSELSYAICHMLGVRAD
>A0A511DT42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sulfidoxydans NBRC 16205|TrEMBL
MSLRAAFAAGRFAVTAEIGPPRGADPDAITRKAELLRGWVDAANVTDNQGAHVRMSSLAG
SVLAMRAGVEPVMQLTCRDRNRIALQSDLVSAGALGIPNVLLLSGDHPRFGDHPDAAPVF
DLDSTQLVATARTMRDEGVLASGREIGARPGWLVGAVENPFAPPRSFRARRLAKKVAAGA
EFVQTQYVFDVEVFAAWLARLRDLGVTEKCKVLAGVGPIRSLRVCEFLRSGVPGIHVPDE
AERRLRGVPAARVAEEGVSMCVETIQRVAAVPGVAGVHVMAFGYERGVPEILERAGIAPQ
PAVSMEGLGHAG
>A0A3S1VWH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.09.1.1|TrEMBL
VTRLEPLKPKFVSVTYGAGGSTRERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIR
DYKSIGINRFVALRGDPASGVGEPYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHP
QSPDFATDIEMLKRKVDNGATRAITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSF
KQVANFSARAGAHVPGWLAERFEGLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTM
NRADLVFAICHMIGIRSHEAAAAGSAAA
>A0A511DNX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sulfidoxydans NBRC 16205|TrEMBL
MVDRLDVDHPLFSVEFFPPKDAAGEAQLWGAIRRLEPLDPAFVSVTYGAGGTSRDRTIRT
TERIASDTTLVPMAHLTAVAHSRAELRHVIGSYAAAGVRNVLAVRGDPPGDPLGDWTPHP
DGLTYADELVTMVRSLGDFCVGVAAFPYGHPRSVDADTDFEHLVAKIRAGADFAITQLFL
EPGGFLRLRDRLDAAGCHVPLLPGIMPLTTVRTLHRGPELSGAPLPEDLVARLDRFADDP
VAFRAAGMDATAELCEKLLAEGVRGLHFYTLNRSPATVELVGRLGLAAARS
>A0A4Q3D1J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium|TrEMBL
MKVTEHITRAQGSTLFSFEILPPLKGETVRQIYDTIDMLIDYNPAFIDVTYHREEYIFLE
RENGLLEKKVVRKRPGTVGICAAIQNKYKVDAVPHILCGGFDKEDTENFLIDLDFLGIHN
VLALRGDAIKSEIYFKSERNGHHYANELVSQIKGLNQGTYLDDYLENNTPTNFCIGVAAY
PEKHMEAASLRQDINYLKQKVAAGADYIVTQMFFNNEAYFDFVDKCRAAGITVPIIPGLK
PIATKSQLSMIPHRFKVDLPDDLVIEVLKCKDNKEVKQVGVEWCIAQCRELKTQGVPALH
FYSMGKSENIKTIVNEVL
>A0A1I5AV93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira briensis|TrEMBL
MESQKKFAPTFSFEFFPPQTPEGVEKLRATRRQLAQLNPKFFSVTFGAGGSTRDRTLETV
LEIQAEGYAAAPHLSCIGATSENIRTMLQKYRDGGIRHVIALRGDLPSGMAQGGEFRYAN
ELVAFIRKEFDDAFHIDVASYPEYHPQANSVQADLQNFKRKVDAGADSVITQYFYNADAY
FSFIDACEAMGIGVPIVPGVMPINKFSQLARFSDTCGAEIPRWIRKKLESYGDDSASIRA
FGLDIVTDLCDRLLSAGAPGLHFYTLNSAGLTTTIWQRLGL
>A0A2T9XS95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. WB94|TrEMBL
MELNHDLLGTVSVDPVRGLAVTATPEASVDARTEAAPRHRATLAPIDRPTVSFELFPPRN
PDAAPKLWATIEALGAARPDFVSVTYGASGKTRDTTRGLVRRLLRETSLNPIAHLTCVGT
SRDEVTAVVEEFLDEGVRSFLALRGDPPLDEPDWHPHPQGLSTAAELVELLREIEARRCS
TSPAQKVRATVRPLSIAVAAFPRGNAGTGSTRAQDVAALLAKQEAGADFAITQVFYEASA
YLELVAEARTAGVTIPIIPGIIPTTDPARLLRVEGLTGVPVPRDLLALLGSVDDEIERHR
IGIRASVDLVNGVLDGGAPGVHIYTFNTHHAALDLLEGAHLGGGAPTAPDQASEPQVAAP
QTDHSPRG
>A0A8I0T0D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter amalonaticus|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGSGKPDMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A0A2TGD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp. Tol-M|TrEMBL
MKTAELFKIKQVLSFEIFPPKRTASIDTMYSTLDELKDLHPDFISVTYGAGGSANNNATL
EIASAIKNSYGMESVAHLPGINLSQEDVLFLLNGLKRNGIENILALRGDINPDIKPCGDF
KYASELVSFIKEHGNFNIISACYPEGHPESNSMINDIRNLKHKVDAGTDQLITQLFLDNS
YYYAFQERAAIAGIDVPIEAGIMPVVNKKQIERMVTLCGVNLPKKFVRMMERYEDNPIAM
RDAGIAYAVDQIVDLFAQGVDGIHLYTMNNPYIAQKIYEAVYRLLAA
>A0A7G8I281|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. M16.1|TrEMBL
MSTALQRAIEAGDQVLTAEVMPPRGADSSHMLAMAASLQGRVHAVNVTDGSRAVMRMSSL
ASCKLLLEAGLEPVLQMACRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAGDQADARP
VNEFESVKLLQQVDALNRGVDPVQGTLPDGATTLFAGCAADPQSRSWSGLQRRLQRKQAA
GARFVQTQMVMDPEALERFQHELAGPLGLPVLAGVFLLKSAKNARFINRVVPGACIPDAL
IHRLECAENPAMEGVAIAAEQVKRYLGIVRGVHLMAIKAEERIPLILDRAGLSSLPG
>A0A1V5WDY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium ADurb.Bin222|TrEMBL
MEENRFLKLLETSPLPVLRDGAMGTLLHSRGVSFDSCFDALNLSEPALVGDIHRAYIEAG
AQLLQTNTFGANRYKLAAHGLEDRVAEINRAGVDLARRVIYASFKDLLIAGDVGPLGVRL
APFGRVQPEEARAAFVEQIAALAGAGVDVISLETFTDLYEIREALAAARQVCELPVIASM
TFTRDDRTLLGDGPEKVAQRLVEMGADVIGVNCSGGPAQIQRILQRMKLAVPGARLAAAP
NAGWPEQVAGRIMYPAAADYFAEYALAFRQIGAVLIGGCCGTTPAHIAAMRRTLDAPPGP
EVELAVLRLLDPEPAENGGETPTHLAQKLAAGNFVIAVEVDPPHTISSHKLLAGASLLAE
VGADVINVADSPMARMRMSPWAVCHLIQQEVGIETVLHFPTRGRNLLRVQGDLLAAHTLG
IRNVFVVMGDPTAIGDYPEAMDNYDLAPTGLIQLIKEQLNAGRDHAGADIGQPTAFFVGG
ALNLDPPEPERELKLLRRKLRSGVDFLLTQPVFQPERAEAFLQRYADEYGPLPVPVLVGI
LPLNNPRHARFLHNEVPGIVIGPEIFERLERADKDAPREGVRIAAELVEQVRPWAAGIYL
MPAFSRYDLAAELVEAVRRL
>A0A8I2B7I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plesiomonas shigelloides|TrEMBL
MSYHAHQLEALNQSVAELDGRINVSFEFFPPRSEE
>A0A6L9YSH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO3E8|TrEMBL
MTNPTKNSFRTAVESGEFLITAEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRHQGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFEK
KLEAGAEFFQSQLICDFDRLEKFMDQIAAGTNKPILAGIFLIKSAKNAKFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSPVNDFVCK
>A0A226R6B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. M13(2017)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVADKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAEALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNGGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7S2V0I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrocapsa japonica|TrEMBL
MAGKKIVDLMQDRAGEKSPWVSFEYFPPRTAQGVTNLEARIERMKALGPMFVDMTWGAGG
STADVTLDISAKCQNKFGLETNMHLTCTNMPQEQIKKALASAKEAGIRNILALRGDPPHG
EERWEATEGGFNCALDLVKYIRKEYGDYFGVSVAGYPEGHPNTISLVEGGMDALSEAEKG
RCRVEESGEVYVCPDSDFEAELDYLKEKVDAGADFIVTQMFFDAGVYESFVKACKAKGIN
VPVIPGLMCVNAYGGFVKMTKFCKTRVPAELASQLAEVAEDADAVKKMGIKVGIELSKRC
IAAGAVGVHYYCLNLEKVVSGIVEGLDLAPPVKVMPKIIDVLAARKAEGKASVSLEFFPP
RTAKGVENLMARLQRMKAVDPVFADFTWGAGGSTSEVTLELTKGAKQKAQVNPNMHLTCT
NMPKEKITGALQEAREAGVTNIVALRGDPPHGEEKWEVTEGGFSCALDLVKFIRQEHGDF
FGISVAGYPEGHPDKIVEVAEGEEGLSEGERKRCRVAVDEATGEKKVWVCRDAAFEEELT
YLKEKVDAGADFIITQMFFDVETYVAFVEACRRRGINCPVVPGIMCINAYAGMKKMTDFC
KTRVPSAIWEALEPIREDAAAVKQFGVHWGTTFCNQLLEAGAPVLHFYTLNLETVTMKIL
EGLGLYQPPVTLESLPAAPAQSTLPPAPPTTADKSTEVATTQPGAMFA
>A0A127QP24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas arenae|TrEMBL
MSRKNFSIEFFPPKTPEGAEKLRVTRAKLAELHPKYFSVTFGAGGSTQKGTLDTVLDIRS
EGHEAAPHLSCLGSSRESLREILTQYKSHGIKRLVALRGDLPSGYGAMDISSGEFRYANE
LVEFIRAETGDWFHIEVAAYPEMHPQAKSPLDDVQRFVSKVKAGANGAITQYFYNADAYF
RFVDEAQKMGATVPVVAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTDSIRAF
GLDVVTQLCERLLAGGAPGLHFYTLNQSPATIAIWQRLKL
>A0A352WS56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MRISSMFKKDRPLYSFELFPPKPNSPIKTIYETLEAIADLNPAYISVTYCAGGNPADNST
FDIACLLQEKYHITPLPHITCITSSKDEINNRLAKYQDAGIENIFALRGDENPHIAAKDD
FRYASELITYIKGRFNFDITGACYPEGHIASPSLEQDIQYLKRKVDAGASHLISQLFFSN
EHFFDFVERCRAVGIHLPIEAGIMPVVNVKQIQKMVTLCGASLPRKLTRMMQKYEDNPAA
LRDAGIAYATDQIVELLAAGVDGIHLYTMNNPYVARRITENIAGIIK
>A0A124EH19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tractidigestivibacter scatoligenes|TrEMBL
MRITDKLAAGQTLSFEIFPPKGEMPLEEAYRVASQIAENKPDWISVTYSAGGSGNSANTV
PIAARIEGDLGVTALAHLTCMGATASDVDSYVDSLRAAGIQNALALRGDRRPGADVVDFA
HASDLIAHLRKTAPSLCIGAACYPEGHVESASLDESMRALRIKQEAGADFLVSQLFFDND
DFYRFREQCLRYRIKLPVVAGIMPFTSVKQIQRMAFNCGASIPAKVVKRLVRAGDDPAAQ
AHAGIEYACEQICDLAENGVDGIHIYSMNHPEIARATHDALVAMGYLG
>A0A380NLG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella criceti|TrEMBL
MVVSLRDKHKAGQFTITVELDPPKSASVTKTFKEAAQLMDRVDAINIADCPMAKLRMSPI
ALAHLIKYRAQIDTIFHLTCRDRNILGLQAELLGAAALGVDNILTLTGDEPARGDHPKAQ
PVFEVDSMGLLKIAHTLNSGFDLAGNPLDEATNFYIGTTGNPGADDLEAEKGKIIRKVEA
GANFIQTQPIYNLEKAKRFIDMVAPLGLPVMLGLIPLKSFKMANYLHTKVPGISLTDDIL
KRMELGGKEAGLEIALETLWEIKKIAHGVHIMPLNDIQTVLYLIDHI
>A0A4U8YLM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoluna butyratoxydans|TrEMBL
MRPKRTPRTASRLEHVLAQGHLAVTSECGPPRGTDGNVLETKGAMLKGYVDVVNVTDNQT
SMTRLCSLAASIRLKQAGLEPVLQMVTRDKNRIALQSDILGAASFDINNILCLTGDHQSF
GDCKTGQNVHDLDSMQLLQVVRQMRDDGTFIGGDAISRPPEMFIGAAANPFADPFEIRVP
RLAKKIAAGAEFIQTQCIYNVDKFEAWMQGVRDRGLHEQTYILAGVTPFKTAGMAKYMRS
RVPGIDVPEELVKRMSDTPKEKQADEGIAICLETIERLKEVEGVCGFHVMAIEWEEKVPE
IVKRAGLYPRPELEEATPMPASAAAP
>A0A135TGG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum simmondsii|TrEMBL
MHIKAMLDESRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREQEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGATF
IVTQMFYDGDNFVRWVGKVRERGITVPIIPGIMPIATYSSFLRRAKHMNCKVPEEWMAAL
EPIKNDDVAVREVGKGLVAEMCRKIVAAGIHHLHFYTMNLAQATRMVLEELEWMPTSDRP
VKHALPWKQSLAHGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSVKDIANIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSTHPVHGWGPANGYVYQKAYLELLVHPDVYHEIVARVEKNP
DMTYYATTKNGNLKYNASNDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGIDW
AHCFEAGSPSRTLVERIMNEWYLINIVNNDFHQKTALFDLLEGLEVKEYSDISAEPQTNG
AAKEQQINGSAPAAAVAAN
>A0A6L8ARZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MASCVNGILTVHNRRLMDFPLKTLRDALRGKDFAVVGQLRLHQDHGRDDLIRQAECLSPA
VDAVAVTDNPYGLVHMSGLAAASILLHRGIDPVLQISARDRNRIALKSELLGAAALGVTS
LVLQRGNKLPKDGQPQVKEVFDTGAKKFLAAAKQLSSFQVAQGSPELFLGTMATVFDPDD
GWQPTEIKAKVEAGAQFVQTQACLNVALLRRYMKFLVAAQVARRCHVLVSVPLLASVESA
RWLAAHHRGAVIPDGLVGQFKRAEDPEAFGITLCAETLQAIREIPGVGGVNLSTTGNPEA
IVAAVNQAALG
>A0A7S6SH81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTEGAGQSAVPSGPASLLERRLAAGAFVVTTEMVPPDSADADDFRSLLAPYRGCVDAINV
PDGPGANCHMSSLAAAALLVREGLQPVMQLCCRDRNLIAIQAELLGAAALGVHNLLCLRG
DDIANGDHGWAQPVFELDSLALIRTAVTLSREGRLCSGRPLAAAPALFIGAAVDPFSGPV
EACVGNFAGKVAAGARFVQSQYCFDVARLEAFMQQVRDQGLHERCAILVGVGLLPSARAA
GWMRGHIPGVHIPDGLVHRLEQSRDPPATGVAICIELIERIRAVPGVSGVHLMLHRHVQR
LAEITQRAGLSRPASRMD
>A0A6N9BTZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGTDRQGGSPGRGAVAGPARTSPRRLSFEFFPPKTDRGRANLLRTATRLLEAGGAATEFC
SVTYGAGGSTRTGTFEAVHALREGGINAVPHLSWGADPAAAMRKFLARYRELGVDRIVAL
RGDIPSGVGPRSQVHHAVELVRLIRESEDDRFQIEVAAYPEVHPDAPSPEADLDYLKQKV
DAGADGCITQYFYHPESYFYFVDRCRTRGIDAPIVPGIMPITNYDGLVRFSDACGADIPR
WIRLRLEAYRDDEASLAAFGTEVVTRLCQRLLDNGAPGLHFYTLNKAPPTLAIAGNLGLA
REAET
>A0A847C0H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadaceae bacterium|TrEMBL
MDLQRRQRFFQLLTERVVVGDGAMGTLLYSRGIAPDTPCERLNLIDPDLIYLIHREYVEA
GAQLIETNTFRANALCLSTLGLAGETRRINREGARLARKAAGEEAFVAGSVGPLPRAATE
AGVLVSARREEIFREQMEALIEGGVDLILLETFASLEELEIAVGAGVSLNVPLIAQMAFF
EGGTTREGFTAESAARRLDRSGIAVLGANCGSGPHGMLGVVKSLSAATDLPLSIFPNSGF
PQRLEGRSVYLASPEYFAARGRELAENGASLVGGCCGTTPEHIRALAAAVDGLKPALRYP
ARRLVIVSRPPEGLKKTVEATFLDDWGRRPVVTVELDPPRGLDPARVMNAARLLAAKGVA
AINLAENPLARIRMGNIALGSRIQEETGIPVIIHVTGRDRNLIGLHSEMMGAWLLGIRNV
LAVTGDPTSMGGEAGASDVFDVTSLGLLRLLSSLNEGRTFFGAELQGRTRFTLGAALNPN
LADLDDQWRRLEKKIEAGASFVQTQPVFCEKVLDRLLKRARSLKVPLLLGIMPLVGERNA
EFLHNEVPGITIPDPVRERLKGKSGEEGVREGLAVARELIDAARGRAGGFYLIPPFGRVE
PALELIDHIRSVAAG
>A0A7W7WLN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora gansuensis|TrEMBL
MALGIPSTRADRALSIRELLATGARSYSFEFMPPRSAQAEVSLWNAIRRLEVLSPTFVSV
TYGAGGSTRGRTVNMTGRIAQDTTLTPVAHLTAVGHSIAELRNILGHYADQGVRNVLALR
GDPPGDPLGDWVRHPQGVRYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDSDIRHFVE
KCRAGADYAITQMFFDVDDYLRFRDRVEKAGCAVPIIPEIMPVTTIRSLERIPTLSTAVI
PAEFTERMTAAQDRPGDVRSIGIEHATQMCRRLIAEDVPGLHFMTMNFSPVTMEIYQNLG
LQNRP
>A0A1A8KX94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius kuhntae|TrEMBL
MVNQVQRVDGSWLSCKSDSSGTSNSGGESSKESSRCSTPVLDAVRSDRLRDKMRRRMESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEEEEGGFNYAV
DLVKHIRSEFDDYFDVCVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTF
LTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIE
>A0A417VIJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium OM02-2AC|TrEMBL
MIEEYLNTQGYMLFDGAFGTYYAQRYAEEQEPCEMANLKHPQRVAAIHREYIEAGADAIK
TNTFSANEQQLECSWEMIQQILQEGYRIAKETAGDRVKVFADIGPIMEQKNVSLAQQYQR
IADVFLAEGAECFLFETLLNTRELHAVSAYIKQRCPSACIIVSFAVTADGYSRQGIAMHQ
LLQDCLTDEHVDACGLNCVCGPMHMKRLLDSIDRSKKPILIMPNAGYPTILANRTYFRDS
STYFAKEMQEIWKKGARLLGGCCGTTPVYIQKTKEALQEQTIVQKTLQPAQQTDKIVRED
HNPLRKKLQKRQQIIAVEFDPPANCEIERFMNNAEFLKEAGVDAVTIADYPIARARVDSS
LMACKLHRELGLEVIPHMTCRDRNINATKALLFGLQIEGIRNVLVVTGDPIPSEDRQEIK
GVFNFNSQLLAGYIRDLNETMFREPFLIFGALNLNAVNFEAELAKAKRKVAQGMEGFLTQ
PVHSRQALINLKRAREELQAYLLGGVLPIVSHRNAVYMNNEISGIEVDDEIIDLYEGTTR
AEAQKLAVAISCKTMDEMRPYIDGYYLITPFHRVEIIADLMKHIHKQ
>A0A0A3IRS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus odysseyi 34hs-1 = NBRC 100172|TrEMBL
MGLLEALKTRILTADGAIGTLLYSYGLDYCHEEMNVTKPEVVQKIHEQYIAAGADIIQTN
TYGANAIKLARYGYEDRVKEFNEAAVKLAKAAAGDTIFVLGTIGGIRGIRKSDATLEEII
TAVCEQARVLLDGDVDGILLETFYDFEEIEAAVRAVRAMTDKPVIAQVSMHEPGILQGGI
SFRAALLELEAAGADIVGSNCRLGPFHTIQAFEKVDLPKRAYLSAYPNASLLDVEDGRVV
YESEADYFARAAEELVKQGVRLIGGCCGTTPKHIEAAKKRLSKLTPLLEKETKPATTEFV
RIPEPPKYEPLHMKARRERSVIVELDTPRHLEIDGFIKGARELYENGADVIMMADNSLAS
PRISNIAMASILIREGIRALPHITCRDRNLIGLQSHLMGLDALELHDILVVTGDPTKVGD
FPGATSVYDVSSMELISLIKQLNEGISFSGKPLRKQATFSVAGAFNPNVRVVDRAVARLE
KKLEHGCDYFISQPVYSKEKIMEIYEATKHLDAPIYIGIMPLTSFRSAEFLHHEVPGIKL
SAEVLARMEACGEDKAKAAEEGVAIAKELLETACEYFNGIYLITPFLRYDMTLQLMDYVK
ELDAQYKGVQTNA
>A0A7S6SHU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPEVEAASAAPAPVQVSFEFFPPKSAAMEASLWQAVERLAPLQPRFVSVTYGADGSTRDR
THNIVRRILRETGLTCAPHLTCVGASREEVLEVVRGYHDDGIRHIVALRGDPPSGESRYR
PHPGGYAYAADLVAGLRQFADFDISVAAYPDVHPEAPSAAFDLDNLKRKFDAGASRAITQ
FFFDVDRFLRFRDDCDRAGIRGPLVPGLLPIAKFSQLLGFAARCGTPVPGWLHQRFEGLD
EDPETRQMIAASVAIELVGRLRRHGVDEFHFYTLNRAELTYAICYALGLRPRAAEAGA
>A0A7C2JTS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MANDELKRHIADFVRDYSIEITPHDAGKLDAIRAELAEGTAVYVAHPPGVPIDDIVSLAG
QVQKLGLKATPHIIARKLESREQLERALARCQELGIVNALCVAGDITAEKPAYNSSLEVL
QTGLFEKYGFREVGVAGHPEGSKAIGAERVEQALNGKAEFAKTAGFNLYFATQFGFDPQP
FIDWEAATTAKGIRLPIHVGMPGPASLRQLAKFAMLCGVGASMRMLTTRTSAMANLLSTQ
APDEMVTALARHKGANPQSRFKKVHFFAFGGVVKTARWANAVISGRFVLNNQGTGFRVED
VN
>A0A348UN14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MRNGLDSQSPTRFTASETRVSLEFFPPRGGDVASIDPVVTRLREARPLFCSCTYGAGGST
RDGTRQTVAHLFELGLDAAPHLSIGTDSEETIHALLDEYQALGVRRIVALRGDVPSGVGR
ARYTHNAETLVRWIRAHSGDHFDIEVAAYPETHPDARTPAEDLEFFRRKVDAGATGAITQ
YFYNVQAWEDFVERATKVGVTLPIVPGIMPITNLEGIVRFSESCGADLPRWIRKHLEALR
DDEAGLKAFGIDVVTRLCEDLLAAGAPGLHFYTLNRWGATAAICRNLGLIGPS
>A0A2M7VZJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium CG_4_10_14_0_2_um_filter_32_8|TrEMBL
MKITEHLSKAKKVLFSLEILPPLKGNGIQSIYDSIDPLIAFGPSFINVTYHREEFVYKKR
EKGYLEKIAIKKRPGTVGICAAIVNKYKIDAVPHIICGGFTKEETENALIDLNFLGIDNV
LLLRGDPIKTEASFIPEEEGHHYAVDLVRQVVGLNQGIYMDEDLQNAQPTNFCIGVAGYP
EKHFEAPNLKNDLKYLKQKIDAGAEYIVTQLFYDNQKFKTFVNLCREEEITVPIIPGIKP
ISSKNQILTLPKNFHIDMPHELVEAIEKCKSDEEVKKVGIDWAIQQSKDLIEFGVPCIHY
YTMGKSLSVREVVKAVF
>A0A2E4LK90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MEAKPXKQYXIEFFPPKXKEGGARLDLAFEKLLELRPDFCSITYGANGSTXQGTKDLTYR
YQXKAGNIAPHISFGDASEEDMGKLLQDYKSAGIRRLVVLRGDQSNGSSKKLPHANELVE
FIRXETRDLFHIDVACYPEIHPESENIEREVKYFKKKVDAGAXSAXTQYFYNPDSYFRYR
DYCYDKGISIPIVPGIMPITNYQNLSRFSANCGAEIPRWLRFRLEKFXDXKPALQEFGVX
VVTELCEXLLSGDAPGLHFYSMNLATSVTRVWDNLDLSKRGRXKRYAHPKALFQGRP
>A0A348DLT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metakosakonia sp. MRY16-398|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRAIAKDYWDNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVEAGANRA
ITQFFFDVESYLRFRDRCASTGIDVEIIPGILPVTNFKQAKKFADMTNVRIPAWMSQMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A2E8XJU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MQEKSENQFSIEFFPPKTISGEAKLDGVFDKLSRLKPHFYSITYGANGSTKKGTQELTFR
YQXMGAXIAPHISFGDTSEKDIIGLLXEYKKSGVGRIVXXRGDLPKGSDEKLRYASELVX
FIRXKTADQFHIDVACYPELHPESDSIKTEVKHFKNKVDAGANSAITQYFYNPDAYFRYR
DYCAQNGINIPIVPGIMPITNYNNLSRFSANCGAEIPRWLRFRLEELSDDKRGLQEYGIE
VVTELCEKLLAGGAPGLHFYSMNLSASVTKIWDNLXLSGKGN
>A0A2D5T615|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAAKITPSVSFEFFPPSNDEMDSMLWQSLGKLSNLKPQFVSVTYGADGSTQKRTYSVVSK
IINETNLTPAPHLTCVNATRDEINEIARRYWDMGIRHLVALRGDAPKECKSYIPHPKGYA
YASDLVAGLIKVADFDISVAAYPEVHPEAKDALFDLDNLKRKLDAGASNAITQFFFDSDK
FLRFRDLCGQAGIESAIIPGILPITRFSQMERFAKICGTKIPKDLRLQFKGLDEDSKIHQ
TIATNAAVAQVKYLESEGIKDFHFYTLNRSEITFAICNALGLKKLS
>A0A534AXY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTQQLQHRAPLPEVSLESIIAGLAREASVEINVQDLRDVEASRAFLAPGRRIFVSFLPKQ
TWEDTAAACRTLKQAGFDPVPHVPVRLLTDEQMLDELVAGLVRDVEVEELLLLSGDYPQG
RGPFSRVEDVLETGVLAKYGLQRVSFAGHPEGHPVVPVEEVRRAERAKTLGAAESGLEVS
FVTQFFFEADPFLAWVEAMRSSGVQVRLVAGLAGPARISTLFKFAMRCGAGPSIRALGAR
PTAFTKLIADHGPQNVLRNLAQAQSSGAADFAGIHLFCFGGYLHTCAWLHRVASGEFCLN
RTGGFDIN
>A0A534FKN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPILPGHSSPGRFERVLRAGTFAVTSELAPPDSADPEDVYRRARIFDG
HVDAINATDGSGANCHMSSLAVCALLTRLGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQALPVFDLDSLSLLETARTLRDEHRFLSGRKITCAPRVLLGAAE
NPFAKPCEWRAQRLAKKVAAGAQFIQTQFCYDVPLLRAFMRQVEELGLLDKVFILVGVGP
LRSVKAAEWIRTHVPGVHIPDGIIKRLAGASDGALEGRKLCIDLIQEIRTVKGVHGVHVM
AYRQEETVAEIIERSGVLGGRVPWYPGRDPQASTNRMAS
>A0A534D0N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNAESGRTPIRVSFEFFPPADEAMGAMLWKSIERLAPLAPRFVSVTYGADGSTRERTHNV
VTRIQRETPLTGAPHLTCIGASREEILEIARGYWDEGIRHMVALRGDPPQGEGARRPNPR
GFRYASELVAALAGLAPFDISVAAYPEVHPEASSAAADLENLKRKIDAGATRAITQFFFD
TDAFLRFRDALAAAGVHAPIVPGILPITRFPQVLRFAKACGTSIPGRLHERFAGLDDDHE
TRRMIAASVAIEQVEALRRHGVSEFHFYTLNRAELTYAICHALGLRPHARSASAALQEAR
A
>A0A523MEA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSDQPRVSFEFFPPSTPKMEETLWNSIQRLAPLNPRFVSVTYGADGSTRDRTHRIVHRII
EETGLRAAPHLTCVGASKTEVQELAQKYWDEGIRDIVALRGDPPEGVGTYVPHADGYEFG
VDLVAGLREVADFEISVAAYPESHPEAPNPAFDLLNLQRKIDAGATRAITQFFFDTDRFL
RFRDNCADLGITESIVPGILPINKFPQLLRFANMCGAKVPQWLHERFEGLDDDEETRRMI
SANITIEMVHKMQAEGINEFHFYTLNRAELTYAICHALGVRPKEKTNGVVANG
>A0A534E3H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPIRPGHTSPGRFERVLRAGQFAVTTELDPPDSADPEEVYRRARVFDG
YVDAINATDGSGANCHMSSLAVCALLTRVGYAPVMQISCRDNHFLSGRKITHAPRVLLGA
AENPFADPIEWRAERLAKKVAAGAQFIQTQFCFDVPLLRTFMNRVEDLGLLDKVFVLVGV
GPLRSAKSAEWIRTHVPGVHIPDEVVKRLAGASDGALEGRRLCIDLIQEIRTIKGVHGVH
VMAYRQEEAVAEIIQRSGVLGGRVPWNPGRDPPANTNRMASEPTPSAALEPARS
>A0A2E4SR44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTEKYLKLKDVLESGKFAITAEIPAPVSASSNEMEEKIKILKGSVHAINVTDNPGATAHM
SSLAGSAIVRNQGIDPILQITCRDRNRLAIQSELMGASALGINNVLTLAGDPVKNGDQKD
AKAVFDIXSKTILTIMDVMNNDGKTMSGRELQTKSSFFPGGAAIVHEPEDNWDPKVLSEK
ASFGARFIQTQFCYDVELVKRYIERIVDTGLSERMYFIIGIGPLRSEKSAKWMKDKLFGT
VMPDSIIKRMEGSNDQIQEGADICAELIESFREIEGVHGAHLMAPRNLSAIPETVKQSGI
TI
>A0A2E8F546|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNKTSAPQFSFEFFPPRTPVGETKLDAVHAELAALGPEFFSVTYGARGTTKVGTRKIVLR
FKALGSTMTPHLSFGGSSEPEVEQLLEEYRAEGIDRLVVLRGDIPSDSSSTVTYRYASEL
VEFIRLKTGDHFHIDVACYPEIHPESSSYDADIGFFKQKVDAGANSAITQYFYNADAYFN
FVENCAAIGMDIPIVPGIMPITNFANLSRFSVNCGAEIPRWISQRVMAFGEDQKSISAFG
IDVVTRLCERLREGGAPGLHFYTMNQAKSVKQIWQNLGLSE
>A0A359BGI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGAPRVSFEFFPPKTPEAEASLWKTVNRLQALRPEFVSVTYGADGSTRERTHQVIKDILT
KTSLRPAPHLTCVGAPQKEIDAIADEYWSMGVRQIVALRGDPEGGAEADYIPHPEGYAYA
SDLVQGLLEKHPFKLFVAAY
>A0A2E3QJD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MFKEAEFLFTAETTPDVTTDLSKTVARIDDLVGLADAVNVTDSPNCKSRLNSLLVASEIK
RNGLDVILQLTGRDRNQIALESXLLGALSVGVNKVLCLSGDQPPAGGPTAVNELNSNGLI
ELCAILSDGALSDGTLIDEPLAIFSGAADDLYEQKSKADAMGKLIKKIESGANFVQTQYC
FDYEVIKEYSEKLSQSGLFEDCKILIGMGPLKSAKQADWMRKNLWGINISDEILRRLELS
DSPSETGEQICEELIEKAMDLPCIHGVHLMGPNCEKRSANIISHFR
>A0A2G6KRR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSGSLEHLSFEFFPPRSAAGKDRLLNDIAPKFSAFSPEFMSVTYGAGGTTRDSTFGVVKR
LRESGVDAAPHLSVGGDDEETIARLLEEYKAIGVNRLVALRGDVPSGMGGFNVIYANELV
AFIRERTGNHFHIEVAAYPEIHPQAESYDKDIYYLKGKFDAGADSAITQYFYNVESYFYF
LDRCAAMGIDKPIYAGIMPITNFQNLARFSRNCGAEIPRWICQRIEGFGDDQQSIRDFGV
EVVTQLCQTLIDSGAPGLHFYSMNQADPTVQILNNLGR
>A0A060JCN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoluna lacicola|TrEMBL
MAETSLLRKSDLNSLSFGNISEISAARRNGAEPTLSFEFFPPKDEVGEANLWNAFEKLLE
VSPDYVSVTYGAGGSNRERSLAVVERMSKQVLTIGHLTCVGATKSSTLEIVKFFEQVGVG
AILALRGDSPKDDPDALSKGELKTALELVDLVREATDLEVGVAAFPEVHPESPNMEHDSR
VLALKQASGAKFAVTQLFFSVQAYTDLVASAQAAGASLPIVPGVMPISNAKQIVRMAELS
GAAIPDELLAKFDQAEDEDQAREIGMAYSTQLAKDLVAAGAPGIHIFTLNHHAAALELAR
GAGLCR
>A0A3B9R081|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MATDTAADTLPDLKSGSNLERVLAAGHFAVTGELGPPKHMDTSVVDRKIDLLKGVVDAAN
VTDNQTGIVRLSSIATGIYMAQHGLEPVIQMTCRDRNRLAIQSDLMGAYIHGIRNVLCLS
GDHQSFGNHPGAKNVQDIDSMQLIRMLQEMRDKNQFQCGDEIKGGGPKLFIGGAGSPFSE
PISFRPLRIAKKMAAGVDFIQTQMIFDMDIFRQFMRRLVDLGVTEKVHILAGIGPLKSSP
MARFLNENIPGIIIPEDLLKRMDGAVQGISEDDKEARRDAWRAEGQDICIEQIEELQQME
GVSGVHIMAIEWEAAIRPIVERAGLLPRP
>A0A2G6L7W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTQKQFNRRFSFEFFPPKTPPGMEKLQVIRNQLAEKSPDFFSVTYGAGGSTQERTVSTV
LNLHKQGIDTAPHLSCIGATQDNLTELLDLYKKNGIDRIVALRGDLPSGMGGHGELRYAN
ELVSFIRKHSGDYFTIEVAAYPEFHPQAVNAEQDLLNFKLKVDAGADSAITQYFFNADAY
FYFIERVEQLGLNLPIVPGIMPITNYSNLIRFSAMCGAEIPRWIRKQLESYGDDSTSIHK
FGEEVVTQMCEKLLDAGCPGLHFYTLNQATPSLNIWNNLNLNSMVSTWV
>A0A349UZG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
GGAGSPFSEPISFRPLRIAKKMAAGVDFIQTQMIFDMDIFRQFMRRLVDLGVTEKVHILA
GIGPLKSSPMARFLNENIPGIVIPEDLLKRMDGAVQGISEDNKEARRDAWRAEGQDICIE
QIKELQQMEGVSGVHIMAIEWEAAIRQIVERAGLLPRPIV
>A0A127R509|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas pratensis|TrEMBL
MAQKNFSIEFFPPKTPEGTEKLRVTRAKLAELHPRYFSVTFGAGGSTQKGTLDTVLDIRS
EGHEAAPHLSCLGSSRESLRAILAQYKDHGIKRLVALRGDLPSGYGAMDFSSGEFRYANE
LVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDVQRYVSKVKAGANGAITQYFYNADAYF
RFVDEAQKLGATVPVVAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTDSIRAF
GLDVVTQLCERLLAGGAPGLHFYTLNHSPATIAIWQRLKL
>A0A2E8NGI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSCIFTVFVLLFLQYLLKGVFVVNKLVDKFNDGAFVVTSELTPPKGTDVSMLLSKAEVLA
PVADAVNVTDSHGSKMSLSPIASAKLLKDXGVEPILQMTTRDRNRIALQSDMMGAWVLGI
ENLICMGGDPPHLGDHPDAKPVFDIPTEQLIKAAKNLNEGCDLMANSLKGNTSFNIGAVV
NPGADDLAGEVNRLEKKVESGATYFQTQAVFDVNLFAEFMEKVKHLDIRVLAGIMPIRSA
KMALYMNDNIPGIDVPEAIIERIEQADDILEESLAISSEIIQGLRHTCAGIHIMAPGWET
NIPTLVERSGLAI
>A0A1Y4SBK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilimicrobiota sp. An134|TrEMBL
MKISEILKKKATISFEVFPPKNKEGDISSIYYTIEELSQLNPDFISVTYGAGGSTKGKTV
EIASTIKNQYNIEAVAHLTCISSTESEILDICQQLKDNHIENILSLRGDYPQDGLQHELS
FHYAKELNTFISQHFPGDFCLSGACYPEVHQEASCLEDDLKALKEKVDAGAQYLITQIFF
DNHYYYRLVKEARKRGINVPILAGIMPVTHSKSLLRTAKLCGCSIPYELSTMIESYYHYP
EAMKEIGINYATHQIIDLITNGVDGIHIYTMNKPEIAKAIFQSIPTVLKELNHE
>A0A806QRD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. BH072|TrEMBL
MGLLQDLEERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIADLGADITGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTDKEVKIRREEEVI
SVRNERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A8B7BYG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phoenix dactylifera|TrEMBL
MKVIEKIRAAGEGEGRTVFSFEYFPPKTEEGVENLFERMDRMVAHNPTFCDITWGAGGST
ADLTLDIANRMQNMICVETMMHLTCTNMPVEKINHALDTIKTNGIQNVLALRGDPPHGQD
KFVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDVIQGEGGATLEAYSNDLAYL
KRKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
RIPPEITAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPTNVFRAKEDVRPIFWANRPKSYISRTLRWEQYPQGRWGDSRN
ASYGALTDHQFMRPRARDKKLQEEWAVPLKSLNDIKERFMNFCMGKLRSSPWSELDGLQL
ETKIIDEQLGEIILKGFLTINSQPAINGEKSDSPAVGWGGPGGYVYQKAYLEFFCSKEEL
NLLTENCKGFPSLTYIAVSKEGECLSNVAPNAVNAVTWGVFPGKEIIQPTVVDPASFMVW
KDEAFEIWTKGWACLFPEGDPSRKLLAQVQRNYFLVCLVDNDYIHGDVFAAFKDV
>A0A1X0TCL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snodgrassella alvi|TrEMBL
MSFTQLSFEFFPPRTEEGRRKLAITRKQLSQYQPEYFSCTYGAGGTTRAGTLQTITDIMN
DGVAAAPHLACIGASREEMINLLQTYKDMGIRHIVALRGDVPSGVGFGHQGLRYANELVA
LIRQEFGDWFHIEIAAYPEFHPQSRSAEDDINHFVRKCQAGADSAITQYFFNADSYFWFV
DEVQGRGIDIPIIPGIMPIASFSKLARFSETCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCDHLLQQGAPSLHFYTLNQAGLVSTICQRLGY
>B8FKU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatibacillum aliphaticivorans|TrEMBL
MAEFKSNSKLERILRAGHFAFTGELGPPRGSSVEHVREKAKPLKGNVDLVNITDNQTAMV
RMSSWAASIIAKEEGLEPNYQMVCRDRNRLAMQGDILGAYAMGINNILCLSGDHMQFGDH
PGAKGVFDVDSTQLINMIKKMRDEGTFQGGAEIEEPPKMFIGGAANPFAEPFEWRVHRLA
KKVAAGVDFIQTQCIFNMEKFRKWVAQANDMGLTEKVYILAGVTPMKSVGMAKYMKNRVP
GMDVPDEIIKRLQGAEKGKVADEGIKIACEQIEEFKEMKGIAGVHLMAIEWEHKVPEIAE
RAKVLPRPVV
>A0A429NSC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC08401|TrEMBL
MALGTASTRTDRARTVRDILAAGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVELIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEIMPVTSVKMLERLPKLSNASF
PAELKERILAAKDDPAAVRSIGIDFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A1A9QJ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albulus|TrEMBL
MRDLLATGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRAGTVKA
TQEIAADTTLTPVAHLTAVNHTIAELRNMIGQYADADIRNILAVRGDPPGDPMGEWVPHP
QGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDKCRAGADYAITQMFF
LPEDYLRLRDRVAAQGCETPIIPEIMPVTSVRQIERFAQLSNAHFPPELKERILAVKDDP
AAVRSIGIEYATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGLHEQS
>A0A1Y4C505|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor sp. An306|TrEMBL
MKIIDKLKQDKVTLSFEVFPPKTSGTYESVAKATQEIAALRPDFMSVTYGAGGGTSDYTV
GIAAGIQDQYGVDVLAHLTCASSTRAHVAQVLDQLKARGIQNVLALRGDIPEGGVPANDY
HYAAELVRDIKTHGDFCIGGACYPEGHPESPTKNADIDHLKAKVEAGCQFLTTQMFFDNN
ILYNFLYRIREKGITVPVVAGIMPVTNGKQIARICKLSGTYLPERFKAIVDRFGDNPPAM
RQAGVAYATDQIIDLIANGVNHIHIYSMNKPEIAAGIQASLSEILK
>A0A086AP43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium hydatis|TrEMBL
MKVTKHIENANGNTLFSFEIIPPQKGKNIQELYDNIDPLMEYNPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
VMALRGDAMKDEQYFMPKAGGNCYAVDLVAQIYELNKGKYLHEVMDIDNRPDFCIGVAGY
PEKHLESPSLTSDLKRLKEKVDAGADYVVTQMFFDNSKYFEFVKRAREMGITVPIIPGIK
PIAVQKHLQVLPQIFRIDLPEDLIIEVDKCKNNAEIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A1I2G3A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoflexibacter ruber|TrEMBL
MKVTEHLKNNQGKTLFSIEILPPLKGESIQNIFAAVDTLMEFKPVFIDVTYHREEYVYRE
IQNGLLKKELTRKRPGTVAICAALMNRYKVETVPHIICGGFSREETENALIDLHFLGIDN
VLVLRGDPVKSEGVFVAHAEGNRYASELLQQVINMNQGKYLDPHLQNPVPTNFCIGVAAY
PEKHFEAPNLSTDMKYLKMKIDMGADYVVTQMFFDNQVYFDFVKKCREIGIDAPIIPGLK
PLTTKAQLSALPRAFHIDMPDDLVKAVEQCKDNESIKQVGIEWCIQQSKELISFGVPCLH
YYTMSKSTAIKEVAQAVF
>A0A5Q8CCH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1A.F.Ca.IN.022.07.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTITRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILHETTLTPAAHMTCVDAARHQVDAVIQEFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A2A9IPJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSSNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILKRLKDKQIKKILALRGDISDESRKEDFRFASD
LVKFIKDYDDSFEVLGACYPDIHPESENRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTI
>A0A1W6LL59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sedimentisphaera salicampi|TrEMBL
MPIENLVQKGVVIGDGAFGTMLYQKGVFINACFEELNLTKPDLIREIHTEYAAAGCDFLE
TNTYAANSIKLAGFGLADKVEEINMRGAELARECAGESLVAGSVGSASTASDAAESDNYL
DDVRRAYAEQIAALDKAGVDLLVFETFADVNAMLAALDAAADNTDRKIIATLRPALNWRE
RGAERIKSALARVAERENVFACGFNCGMGPSDMLELLDETRELTDKPFCIQPNAGLPQNV
DGRSIYMCTPEYMAEYSKRMYEKGADIIGGCCGTTPEHISEIAKAVKGVSKADQKARVYS
VKASGQDEKLEKPVVPLEERSLVGRKLANNDFLTTVEITPPRSISLESTAEKAEKCRSAG
VDAINIPDGPRASFRQSALATAVRIKQAGISPILHVCSRDKNIISLQSDMLAAASMGIND
MLFVTGDPPKVGDYPDATGVFDVDAIGMARMARMLNSSRDIAGSEVPDATKMTIGVGVNP
GANDFEREIERYKMKVEAGAEYCVTQPVFDLDTFFRFTDAISGYEIPVIAGIWPFTSKRN
AEFMANEVPGIVVPKELIDRMGKADNKEDAAKTGIDIARESIEAIRDKIAGLAVSAPFGK
VDLAISVIQ
>R6GD62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum CAG:234|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A1C3JI71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio celticus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A225TQV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. BUPNP1|TrEMBL
MDRLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERLGPAFVSMTYGAGGSTRDRTV
RVTGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWEK
HPEGLEYADELVRLVRDLGDFHVGVASFPEGHHRSPDLDHDTRYLVQKLRAGAEYSITQM
FFDVEHYLRLRDRVVACDAEQGLKPIIPEIMPITSLRSARRSLELSGSHLPPVLEERLRR
AAGDGPEENRAAVREVGIEVATEMCERLISEGAPCLHFITLNFARATGEVLDRLGYELEA
PAVVQPA
>A0A0F2PPW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium BRH_c4b|TrEMBL
MSKLQQVLETGNFAVTAEIGPPKHASAEGVRHHAHMMKDYVDATNITDCQTAIVRISSIA
TGVHVMDCGIEPIVQMTCRDRNRIAMQADMLGAYSLGMRNLLCLSGDHQKFGNHPTSKNV
YDVDSMQLIYLVKRMRDEKKFFSGEEIKEHEPQFFIGAVANPFADPFEFRVDRLEKKVEA
GAQFIQTQCIFDMERFERFMEMVRERGLHERTHILAGVTPLKSWRGAKYMQSNVSGMIVP
EEIVQRLKSAEDPKKEGVDLCIEQINYIKDNIKGVHGVHVMAIAWEEIIPEIVQRCGLYP
RPKFED
>A0A3A8JYL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus carmarthensis|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTVEELAPLEPGFVSVTYGAGGSTRDRTV
ELVTHIKQHTGIEAMAHLTCVGHTRDELRDVLRRLDAAGIENVLLLRGDPPQGQTTFEPV
PGGFRYAEELVRFVREEDFNFCIGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRVGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVGALKGRS
>A0A3E0DSR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinomonas pollencensis|TrEMBL
MKSELATKFTDPSRGVYFIGTTPPRASVEEEQLNQISQKLLQRLDNIDVDGLIVYDIQDE
SSRIDKPRPFPFMQTHDPRAWSKRLKDAAQIPVITYKSVSSRTTEEFTLWLQEAWNEFDI
SDIVLVGSPSSDGDIKLPLAEAYKTLANTPLDFNLGGVTIAERHAKKKDEHLRLINKSEA
GCEFFISQAVYNPQATADLISQYAQTCKAQGITPKRVILTFTPCGSAKTLEFMEWLGISV
PVATKNRILGSATPLDESIKICRSALELIMETALPDGVPLGLNIESLTNRKEEIDASIDL
YKLLKATLDLKLAEQALL
>A0A1W6PUX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. NXC14|TrEMBL
MALKSEGRGRNFGISFEFFPPKSEEMEAQLWDAVAKLQDWDPDFVSVTYGAGGTTKAPTL
SAVTRFLSQTPLATASHLTCVGATKEETHQMIDTFRKVGVKHFVALRGDAPGGVGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGISIPIVPGIMPIQNLTQLKRFAGACGAVIPAFLDERFAGFDD
KPEDRAKVAAEVAAEQIEDLVRRGIGDFHLYTMNRAPLVSAVLDNLGYSRRAPKSAGAAA
>A0A1H9FFH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobius taeanensis|TrEMBL
MTTPAISFEFFPPQNLEASFRLWDTVQVLAPLSPRFVSVTYGAGGTTRDLTRDAVATLHK
NSGLNVAAHLTCVDATRAETLAIADSFAAAGVTEIVALRGDPPKGTAGFTPHPDGFAHSV
ELIEALADTGKFKIRVGAYPEAHPEAPTATADVEYLKRKIDAGATEALTQFFFEAETFFR
FRDACAKAGITAPIIPGILPIENWKGARNFAKRCGTSVPAWVDDAFEKAARDGREDLLAT
ALCTELCSELLDGGVDSLHFYTLNRPELTRDVCHALGVTPRAQLENVA
>W4S8U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. pruni str. MAFF 311562|TrEMBL
MLTRSAGPAAMTHLSFEFYPPKTDDQRAQLDRTAARLRGYAPEYVSCTFGAGGSTLSYTS
ETVRHLKQKHGFDAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDL
RYASDLIAFIRAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYN
ADAYFHFRDAVQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWISKKMQSYGDDAD
AVRAFGAEVVATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A5R2N9B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2D.F.Ca.ET.145.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHEVDAVIQEFTDMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGAGDFDISVS
>A0A3R7WME8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Puniceispirillum sp. TMED213|TrEMBL
MHPHPAPHGVSLNGLYPXNYTSEVQIKADRQSKLSFEVYPAKTEKAQKALLSELRLLSPY
RPTFISVTYGAGGKSQAGTADTAKQIQKTLNTDVMAHLTLAVQTRDDVLATADRFSAAGV
RQILALRGDQPHEAVSLPQNPFTDTVELIRCLAARGWDNIRTSAYPDIHKEATDADSDFD
WLLAKFDAGASEAVTQFFFNADNFFRLRDRLDRYGLAKKLIPGILVFREIEKMIGFAKKC
GVHIPARLHVELSRSRQTDVEEAHCLSILLDLLLRLSSQGVXQYHFYTLNKAQPLVTLLD
LLDLPKQGICAVADRQPETCY
>R9L231|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adlercreutzia caecimuris B7|TrEMBL
MEPVASLFAPRSIPFSVEMFPPKGSLTLDAARKVVGGMALARPDFISVTCSAGGSGNGGQ
TIEVASLIQSEAHIPAVAHLTCVNSTRETVQAAIAELKAAGITTVLALRGDLVGNAQPGD
FRHGADLIPLLKDAGFCVGAAAYPEGHLDCLDLDEDLRHLREKQDAGADFFVTQLFFDND
DFYRFRERALAAGVTRPVTCGVMPFLGKSQIQRMVFLCGSSLPSPIVKLLAKHEDDPAAL
RAAGVEYACRQLVDLARNQVDGVHVYSMNHPDIAQAAATALADAGFRA
>A0A2L0I087|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ACNIH2|TrEMBL
MPLLTDSLQNQPFSIFLEYLPTKHAQLVPSCIAGYPVTMTIADRVRSDDDPEPLAIAQNY
AAEIPKILHFSGKGRDIADFNEFIRAIQEQGYSNVLLLTGDKLKHHQDGQDVNLPRTRYL
ESVNAVMQAKKLAPQIKVGVALNPFKYAKAEHDAQYFKLDKKVQAGADYVVTQLGFDLDA
LKEAKQYLNKLPSCLDLFACVMPLTAARAEFMVKHKVAGIVLTPHLLQLLKHEQSVDVVI
AEQNVYARCALQILICRFWGFAGVHLSACHKAEEQKKLEQALERFQDFSFERCMQIWSEL
HQLKSGDELKPKPDVFQKKVSSEQMLKYKSMQFMHDSMFDSKIARNVGRKLFNPKLWSGQ
FANKLLIKSEYMSKHGVVGCESCGQCRLADTLYICPETCPKGLANGPCGGTNLDRCEFGD
RECIHSVKARLAEQTNQIAILKERLIDTVPIELRGTSSWVNWFNPK
>A0A538UA04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium|TrEMBL
MLAPLLERLAQGPLVADGAMGTLLYGRGIPFSESFDELNLSRPALIESVHRDYLAAGAEM
IETNTFGTNAVRLAPHGLEQEVGMIARQGVKVARAAREIVGINAFVAGSIGPLGKPLEPF
GHIAAAQAEAHFRAVAEGLLEGGCDAFILETFQDLNEILAALRSVRRVTLDLPVIAQMTF
GTDGKTLYGHTPTLAVQMLKQAGAAVVGVNCGVGPQPTLEVLEEMVRAAEGTPVSAMPNA
GLPQMVEGRYLYLSSPEYFADFAARAVDLGVRIVGGCCGTTPAHVKAMRDRLALHLPAER
LSPGAEVRVLEAAPAPVAVPEVVAEPALLRMLREKFVVSVEIDPPRGINTTKVMEAARLM
AQRGVDCVNIADSPLARIRMSAMALAYQIHLHFPRLELILHFTTRDRNLMGLQSDLLGAH
ALGIRNILCLTGDPPSLGDYPNATAVFDTDAPGLMRIVHGMNHGTDLAGTSIGAATGFAV
GCGVNPTAPDLDQEFEYVRRKLDAGPQFVMTQPVYELDCWKRFVERLSGLTEIPILVGIL
PLQSFRHAEFLHNEVPGILVPDWIRARMHQAGNEGQKIGVELARELLAACKGMANGVYLM
PSFGRYENCLDVLTDAR
>A0A1I2L426|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. CF614|TrEMBL
MTAADRPAERPLFAGLPGDISVSFEFFPPKTEKMEEQLWDAITQLAPLGPGFVSVTYGAG
GSTRERTHATVARLVRETDLVPAAHLTCVGASKEEIAEIADQYWEAGVRHLVALRGDPPP
ADGGFVPHPQGYASAAALVAGLKARHDFDISVAAYPEVHPEAVSAEADLDNLKRKIDAGA
ARAITQFFFSTDAYFRFLDKVLAAGIAAPVLPGIMPVTSFAAIRRMSGNTAIPGWLETMF
EGLDERPGPRALVAAVAAADLCKRLYEGGVRDFHFYTLNRAEQAYAICQLLGLRPKG
>A0A0E9MCF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuricella sp. T08|TrEMBL
MSTNKPILSFEFFPPKTQEGMDKLHATRKQLGQLNPEFFSVTFGAGGSTRDRTLETVIEI
QREGHEAAPHLSCIGSTRESIRAILNEYKSHGIRHIVALRGDMPSGMASAGEFRYANELV
EFIRTETGDWFHIEVAAYPEFHPQAISAQADLANFKRKVDAGANAAITQYFYNADAYFNF
VDECQAMGVTIPIVPGIMPIGNFSQLARFSDACGAEIPRWLRLKLQGYGDDSAAIRACGL
DVVTSLCERLLKGGAPGLHFYTLNQAGLISTIWQRLGL
>A0A6N9ZNB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium laguerreae|TrEMBL
MALKNEARGRNDIRVSFEFFPPKSEEMEGQLWHAVSQLQDWDPDFVSVTYGAGGTTRAPT
LSTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQ
PHPGGYANAAELVAGMKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQ
FFFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTVIPDFLDERFAGFD
DKPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLENLGLSRRQTKSAGAA
A
>A0A6L8WB41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sneathiella litorea|TrEMBL
MIMSGIPHNREVSGKLLGAKANNRVEVSFEFFPPTSDALAEKHWQALTRLAPLNPKFVSV
TYGAGGSTRERTHSLVSRIRQETALEPAAHLTCVGATRDELEEVAEQYWSSGIRHLVALR
GDPPEGYASFTPHPGGFAGSVELIEFLRKKHDFEVSVGCYPEIHPDAKSSLADIDYLKRK
MDAGATRAITQFFFDPEVYLRFVDRARAHGITIPIVPGILPVTNYSKIRQFSSQCGTQVP
AWLTHLFEDLDEDPATRNLVAAMVASEQCLQLQRAGVTDFHFYTLNRADLVYSVCHTLGL
RPEQSTVTA
>A0A7I8BMN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. PGU16|TrEMBL
MNPIELSFEFFPPKTQEGLDKLRATRAELLPLKPKFVSVTFGAGGSTQQGTLDTVLDMAK
DGLEAAPHLSCIGSSRESLRAILNEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFRIEVAGYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DAHKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VADLCRRLVEAKVPGLHFYTLNGSAATKAICERLGV
>A0A832MLG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium|TrEMBL
MPSPLLDRLARGPLLADGAMGTLLYERGVSYDDCFDELNLSRPTLVEEVHRDYLAAGAEL
IETNTFGCNAVRLAAHGLEDKVRLIARQGVKVARAAREIVGTPAFVAGSIGPLGKPLAPF
GPLTLADAERHFHAVAEGLLEGGCDAFLLETFQDLNEILAALRSARRVALQMPVIAHVSF
GLDGKTLYGHTPAQAVTALLRAGADVVGVNCSVGPQPMLEILEEVVAAAGEAPVSAMPNA
GLPQFSGGRFHYPGSPEYLAEFAARAVDLGVRIVGGCCGTTPRHVRAMRERLASHLPAEK
LPSGAEVRVLERSPEPVAAQAGREEPSLLRKLRERFVVSVEIDPPRGTNTAKVMEGARLM
AQRGVDAVNVADSPMARIRMSAMALSYQIHHHFPRLEIILHFTTRDRNLMGLQSDLLGAH
ALGLRNILCLTGDPPSLGDYPNATAVFDTDAPGLMRIVQRMNAGTDLAGTSIGAPTNFAY
GCGVNPTAEDLDAEFAWVAKKLEAGPQFLMTQPVYDLESWKRFVDRLSGLTDIPVLIGIL
PLQSYRHAEFLHNEVPGIHVPDWIRERMHRAGNDGQRVGVALAQELLAQCRGLANGVYLM
PSFGRFENCLEVLDARP
>A0A0K0SSP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilus sp. TWE2|TrEMBL
MNNKLSYSFEFFPPKTAEGMANLRNVRNELAAFSPEFFSVTFGAGGSTRDRTMESVLEIQ
AEGHGAAPHISCISSSKEEIRELLQAYQAKGIKRLVTLRGDIPSGEVSAGDFKYANELVS
FIRAETGDWFHLEVAAYPEFHPEAGSAQKDLENFKRKIDAGADSAITQYFYNVDAYFRFV
EAAQKMGVAAPIIPGIMPIYNYTQLARFSNVCGAEIPRWLRLRLEAYGDDLSSLRAFGVD
VVTDICAKLIASGVDKMHFYTLNQAGIIGQIIRQL
>A0A160VNI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium freudenreichii subsp. shermanii|TrEMBL
MLDNYRPADLAPARRSNTDTTQTIAELLARAERPTFSVEFFPPKTDEGARVLHEAIEKLE
PWNPDFVSVTYGANGSLRDRTLAAVRDMVASTKLRVVGHLTCTGQSVDELKSVIDAYGDL
GVHHILAVRGDMPGGPRQPWEPHPQGLKNATELVELVKSRGDYCVGVGAFPDIHPGSTPE
QDVRVLHDKQDAGAEFAITQLFFRPSAYYDLIDRMRADGCTLPVIAGMMPVTAISQLDKF
AELSGVPLPASVTERLMAVANDPLAVRATGAQICAELASDLLERGAPGLQFFTRNRSAAT
REILAILLARRPW
>A0A0P0D486|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algibacter alginicilyticus|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPKKGTNIQDLYDNIDPLMEFKPPFIDVTTSREEYVYID
RGNGLLDKRITRMRPGTVGICASIMHKYKVDAIPHLLCGGFTREETEYVLVDCHYLGLDN
VMALRGDSMREEAYFKPVKGGNAYASELVSQIADLNRGKYLHDDFKVEHNSDFCIGVAGY
PEKHMEAPSLTTDLKRLKEKVDAGADYVVTQMFFDNNKYFEFVDKARAAGINIPIIPGIK
PIAVKRHLQLLPQVFKIDLPQDLIDTVEDCKDNKAVRQVGIEFAIKQSKELKAAGVPVLH
YYSMGKSDNIQAIAEALF
>A0A1E3HWD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus amylolentus CBS 6039|TrEMBL
MHLCCTEMPKEKVEWALKQAKQNGCQNILALRGDPVAGTSTWEPTPGGFMNAIDLVKYIH
KNYPGDFCVAVAGFPQGHPESPLTPEGKEQEMKWLKEKVDAGADFIFTQMFYDTDIFFDW
VKRVRAAGITVPIIPGIMPIQNWEKFDKWVQRENIIVPQHFYDALNPVKGDDEKVRQVGT
KLVAEMCRKILDNKEAGIKGLHVYTLNLEKGARMLLQELGFEGRREQIAPLPWRPSLTPN
RRDETIRPIFWANRTRSYISRTEDWDEFPNGRWGDSRSPAYGDLDGYPVSIGISATEAYN
LWGNPTTTTEIYNLFARFCRGELTKLPWSTQPPASETSVITDQLTKMNELGYLTINSQPA
VDGVASDDKVHGWGPSGGYVYQKAYLEFFVSPELLSPLIRRIERDPRITYYAVNKQGDLR
TNTHSEGPNAVTWGVFPGKEIIQPTIVEAVSFVAWKDEAFELGLQWANLYPAGSPSRELI
TKVMNDSYLVNIVANDFRDGLSIFEPFLLDQTPVGKVVEGVKGVVEGVVEGVKSVVAE
>A0A330GXV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium atlanticum|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A319AMW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus lacticoffeatus (strain CBS 101883)|TrEMBL
MGSAVRHGAFSGGSIGGRKSCSSPPPSFTPSFLAFHSLSSVRHRVAVSAAAETGLIMEKI
TDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGSTAARS
LELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMH
GEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDGQDPARDLPYLIEKT
QAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTKLSHV
KIPPHVLSKLEEVKHDDDAVKRIGVDIISDLVHGIRDLVSPGLRGFHFYTLNLEKTVSFI
LERCELIPPYTEIDDSDALADGGNLSALDSSSYIAPNGAPIRTLASRRSSVSSIPHNRVI
VDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWSEGGA
EEDSNGLNAETAIIQPELLTLIDKKGWWTLASQPAINGVRSDDPVFGWGPPGEGFVFQKP
FVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNTDDPDPIDINPANV
NAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDDTKNDVW
LVCVVGQEFGAGTEPGSEEEEDEKKWMWRELANSQ
>A0A0B7MZX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasitella parasitica|TrEMBL
MKVIDKIHKAEQEGRPFWSFEYFPPKTAQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
DLTTEIVATAQSVYGLETMMHLTCTNMPVKQIDDALEAAKNCGCQNILALRGDPPKGQAN
WESCKEGFEHAIDLVRYIREKYGDYFCIAVAGHPEGHIDNPDKEDDLLHLKKKVDAGADL
VVTQLFFDIDSFLAFYKKARAIGITVPILPGVFPIQNYTGLKRVISFNNNFVPQKIWDDL
EPIKDDDTAVKEYGINLTIEFIKKFRETGVNGFHIYTFNLERSSRLVLERLSLVAPVESI
KPLPWNPSLTSKRAKENVRPIFWKNRAKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
INLKYPVEQCIDMWGSPTNIDDVAQTFARYCKGQIAGIPWSAQQLDAETDIIRQRLAAIN
LLGYLTINSQPAVNGVRSSHNVYGWGPKNGYVFQKAYLEFFVSPEKLNELIEKIGKDAQV
TYYAVNKQGDLRTNTQSDEPNAVTWGVFPGKEIVQPTIVEAVAFMAWKDEAFELWNRWAR
IYERESESAELILDITKTWYLINIVHNDFQDENGIWKLFDLEIDGEISRKLLQSNAVAR
>A0A0A2A2K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus str. MIT 9201|TrEMBL
MKSKLQQTLEKKSKVITAELMPPRGGDPLRSLKIAQLLKEKVHAVNITDGSRAVMRMCSL
AMSKLLLENGLEPVMQISCRDRNKIALQSDILGANALGIRNILCITGDSVKAGDQQNAKA
VHEFESVKLLQQIQAFNNGIDPTFGELSDEKTYIFSGAAADPNCRNKRSLENRIRKKKEA
GAGFIQTQMVMEKENLIEFCEKISNPLEIPVIAGVFLLKSYKNALFINKYVPGANIPEKI
LNRLKDAKDPLQEGIKIAAEQAHDFINIANGVHLMAVKAEHLIPEIIEKAGLSLEY
>A0A1I2RZ00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. CF614|TrEMBL
MVKPLIHPNWERAPDGVTDGYSLEMTAKDIESLRAAAALMPVDTPVAVTFLPGEEPAARV
AATRAVRDLGFEPMPHFSARRITSQAEFEDYLQAVVHEAGVKRCFVVAGDPPEPQGPFFD
TSALIATGAFERAGIKAIGIGGHPEGHPNMNAAQCWQVLEAKVAEIERRGMAPLIVTQFS
FDPDAVLAWLEELRAHGIDAPVRVGIPGPAGIKTLLRFAARCGVGASASVMKKYGISITN
LIGNAGPDKLVDTFAARLGEEHGPVRLHFYPFGGLVRTVEWIAAYAKA
>A0A5Q4FYC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trueperaceae bacterium|TrEMBL
MRVSIELVPRDRAVLRRQLDDTLALGAAVGAVNLPDLLRFDLRSWDAACDVRRDSASTGR
PLAAIPHVRAMDVPLDRPWAPAERLDAAGIDEVVVVQGDPPDDMRHDLSGASSLQVIAKL
RAQRPAWRIYAALDPYRQSIAAERDYALRKLDAGADGFFTQPFFDVRLMAAWRDLLPDVP
VFWGSTSVTSERSLRYWVSRNRAVFPSGFEPTLEWHRRFAVAFMEHARSEAASVYFMPIR
VSIRDWLSEALAR
>A0A3S7KNA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. ESTM1D_MKCIP4_1|TrEMBL
MTAISFEFYPPKTDEQRGQLDRAAARLKTYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCRRIVALRGDLPSGMGFPGDMRYAAELIEFI
RAEHGDAFHIEVGAYPETHPQAPDALTDLKHFKAKIDAGADAAITQYFYNADAYFHFVDE
VRALGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMLAYGDDSASVRAFGAEVV
ARLCQRLVEGGAPGLHFYTLNLAKPTVSVLALLDA
>A0A409Y559|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gymnopilus dilepis|TrEMBL
MAGAKLSELIDAQSPSKPFYTLEFFPPRTDQGFENLMSRISRLSTLDPLAISVTWGAGGS
TKDRSLELAGLTQGSGLTTILHLTCTNMEMGLVDEVLKAVKGQGIQNILALRGDPPRGKE
EWIPSDPRFTHAIDLVSYIRSVPEYSSWFCIGVAGYPDGHADSPVDEDTEIQRLKLKVDA
GADFIITQLFYDVDHFIKWHAKVRQRGITVPILPGIMPIQTYSSFARVTKLCGARVPETV
AAELAGISHDDRLVKDYGVTLAVQTIRRLQSEAGMNGFHFCTLNLEKSVQRILETLGYVG
SLSIDHNKLIVEPPGTPSHPPPDGTSELLTTPSNATSTATQGLSALAATDEAGRGELNNA
ASWDDFPNGRFGDYKSPAFGNQDLYGGSGISKSEFLSSWGHPKTEDDLTQMFIDHLQGKI
AATPFSPTPLSPESLIILSQLEKLNRRGWWTVGSQPAVDGADSSNEVVGWGPRAGYVFQK
CFVEFFCPEEDVSKIERKIQEKGKDIVHYFAGNYKGDCRTNVPEDGRNAVTWGIFPGQEV
VQTTIIERESFLAWKDDAFSIWSEWASFYRPESEERKLLEGIRDNRWLVSIVHHDYKDSE
GLWTFLLDDKAETVSL
>A0A829NRN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter capsulatus YW2|TrEMBL
MNTPHVSFEFFPPQTLDASFRLWETAQVLAPLKPGFVSVTYGAGGTTRKLTHEAVAAIHK
NYGLNVAAHLTCVDATRAETQEIIDAYAEAGVTEIVALRGDPPKGAARFTPHPDGFASSV
DLIEWLARDGRFTLRCGAYPEPHPEAADTLADVRWLKRKCEAGATSAITQFFFEAETFFR
FRDACVKEGITAKIIPGILPIQSWKGAKGFAQRCGTSIPTWVEEAFDHAIRDDREQLLAT
ALCTELCDNLIAGGVEDLHFYTLNRPQMTRDVCHALGVNPDVVLENVA
>A0A6G6J726|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas nitroreducens|TrEMBL
MSQKDRRFSFEFFPAKTEAGHEKLLATARQLAAKKPDFFSCTYGAGGSTRDRTLTTVLQL
DGDVQVPTAPHLSCVGDTKAELSALLAHYKDAGIRRIVALRGDLPSGMGMASGELRFANE
LVEFIRAETGDHFHIEVAAYPEVHPQARNFEDDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAEKLGVSIPVVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDIASIQAF
GEQVITDMCERLLEGGAPGLHFYTLNQAEPSLALWNNLKLPR
>A0A409VNV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gymnopilus dilepis|TrEMBL
MKISQKFQQNSKDDKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPKEKVDVALKDAKKHGCRNVLALRGDPPMGKDE
WEAVEGGFVHGIDLVKHIRREYGDYFDIAVAGFPQHMTLPPDELKQEIQWLKEKVDAGVN
FIFTQMFYDAQLFIDWVKAIREAGITIPVVPGIAPIQTWNGFQRATSLAKITVPQSFLDA
LEPVKNNDEKVREIGTKLVADMCRKILNAGIGVRGLHFYTMNLEKGTKMLLEELNLVPRI
ETIKPLPWRQSLTPNRRSETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGHPTTFSDITSLFARFCTSDLKALPWSDQQASSETSVIASQLA
RINELGFLTINSQPAVNGVRSDDKVFGWGPSNGYVYQKAYLEFFVNPTLLDLLLTHIERD
SNITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAYELGAQ
WAKLYEHDSPSQKLINELMETSYLVNVVHNDFHDSDAIFKPFYKAGAEYIALQSKTNGVN
GH
>A0A8C8YTP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prolemur simus|TrEMBL
MVNEARGSGGLNPHSEGSSSGSENSKDSSRCSTPGLDPERHEKLREKMRRRIESGDKWFS
LEFFPPRTAQGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSQEEITGHLHKAKQLGLKNILALRGDPTGDHWTEEEGGFNYAVDLVKH
IRNEFGDYFDICVAGYPKGHPEAESLEADLQYLKEKVSAGADFIITQLFFETDTFLHFVK
ACTDMGVTCPILPGIFPIQGYHSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIEL
AVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWAVSAHPKRREED
VRPIFWASRPRSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFEVFVHYLSGEPNQNGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKVKKPAGGRLCPTFLLPS
PGSPRNPTLLCSSPSPGLHCQT
>A0A2D1UAU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter ginsengisoli|TrEMBL
MFLDKIKSGQSGILTYGITPPKSETSPERVAEIANRTMARLIPLDIDALIVYDVQDESAR
TSEERPFPFLNAYDPFTFASKYLGDFEIPKIIYRPAGKFSAKELSNWLNDLHEYGFYPVF
VGVPAPDFPVKISLTDAYDLWRTHEKHSVIGAVTIPERHEVLKDEDKRILGKAACGVSYF
ISQCIFNVDYAKKVVDDLCQTCREHQTVPPTIIFTLTACGSVKTLHFMEWLGIHIPDQLK
EELRHTDNMLEKSVSVCLDIATELIAFCAERCVPFGFNIESVAIRKDEIEASIQMVNQIA
EMLEQKGIRKTAAVPVQKVIRL
>A0A7K5LXL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cardinalis cardinalis|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRRVLQGRRGEVFDHMGAGGPLFIDVTWHPAGDPGSDKETS
SMIIAYTAVNYCGLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEE
VDGFNYAVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVYAGADFIITQ
LFFRPETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIK
DNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLP
WAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYL
KSKSPREELLKMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLK
DQLERVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVRALLKV
LRKYELRVNYHIVNVKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAF
ALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A836ESB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoatta argentina|TrEMBL
MRNLILENDMCERNDADGNDNSSTPDFHIENPRKTVVDLRQLLKDKISKNEIFCSFEIVS
TKKSDAFYRRLLIDMEEYSPLFYALTWHNEAASDNDGYLPLDLVENFPVNTLLHLAAKSL
KRDEVIYILKKAIAFGIINIFALRGDSLSENGDFEHAADLVVFIRQRFGNTFCVCVAGYP
QMHPESPSKKLDLHYLKAKVEAGADFIITQICFDSRVLINFVRDCREIGIQIPILPGILT
PTNHACLEKMIDICRLDVPIKIKEDLAQMKDDDQAVRKYSVDLIVQIITDVIRNGATYGF
HLFTLNRLSVVTEICKRIESFKAENL
>A0A1F9PQS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca sp. RBG_16_60_12|TrEMBL
MSVTTPSKLQKMIDSGNLAVTSEVGPPRSADGAIIEHKGNLIKDHVDAINVTDNQTSVCR
VCSLACCIRLKLMGLEACLQMVTRDRNRIALQSDILGAASFGINNILCLTGDHQYFGDHA
KCANVFDLDSIQLIQTVRMMRDEGRLLGGFEFEVRPQMYIGAAANPFAGPNVAMRVSRLA
KKVAAGVQFIQTQCIYNLDKFKEFMKIMVDRGLHEKVAILAGITPMKNVGMAKYMQKRVP
GLEVPDEIVRRIGGVPKEKQAEEGINLAVEQIQELKEVEGVRGFHIMAIEWEEKVPEIVE
RVGLYPRPQLA
>A0A811IFX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus thermophilus|TrEMBL
MTSQTPSLSFEVFPPNPAVGNKKILLALDDMKGSAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRELDAVGVNRILALRGDIIPGVEPLKDFRYATD
LIEFIKAEAPNFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIYAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETARHIYEATHSLFKHHSQVGAL
>A0A343TG94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halalkaliarchaeum desulfuricum|TrEMBL
MTRDDITALLTDPRFELLPFDSFYDQADQLPEGSKIAVTASPDLGVDRTVEVSLDAVERG
FEVTPHIAARGVSDVDHLQDIADQYEEAGISDLFVVGGDNEEPVGEFESAHDALVALAEH
GYDFEEVGIGGYPEGHQKIDDDTLAEALEKKSPYATYAVTQLCFDPEAIIEWTDEVQDRG
IDLQVHVGIPGVVKYQRLLQISRKVGVGDSIGFLRKTTGIIGFVKQLVGSRGNYTPDRLV
EELAPYGADPDYPIEGVHLYTFNQAADTEKWRRELV
>A0A1F9P532|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca sp. RBG_16_60_12|TrEMBL
RDRNRLALSSDLLGAASLGLENLLLVSGDYVTLGDHPQAKPVYDADSVQLLQIAAGLMDG
HDSAGLPLTGSPVFFLGAVVIPEAEPLPPQLIKFEKKLAAGARFFITPPIFDLDKLRRFR
EHLPETPVKLLAGVKVLGADEVALAAAGQWRQVYSLPPDLVRDLAGKEPEEVMARGVEAA
GRLVKQIKQEKLADGVYLKAKGRTDLFTQILKGAGL
>A0A2E0PV54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Legionellales bacterium|TrEMBL
MESQKQYKPKFSFEFFPPKTRQAVEKLQMTTERLAQLNPSFFSVTFGAGGSTRERTFETV
MDIFKKTGIDGVPHVSCVGSTLEEIQIILDSYIEGGIRNVVALRGDLPSGSIGGGPLRYA
SELVEFIRRETGDHFHIEVAAYPEFHPQALSAQKDLENFKRKIDAGADAAITQYFYNPDA
YYRFIDSCEKLKINIPIVPGIMPIVTCTQLCRFSDACGAEIPRWILKRLQEFGDDRASIQ
EFGIDVTTKLCEELLANGAPGLHFYTMNQSEASVAILKNIGINMKD
>A0A149RZL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter japonicus|TrEMBL
MIRSIGQVRADLMTESSIELLPSRILELSGVLPDLDRGSRVFVTWLPGVPFAEVLAACDL
LKLCGYLSVPHVAARSIRDTEHLRNICAALIERDIPRMLLIAGGADKPAGIFTDTVQVLE
TEIPAQAGIRTVYVAGHPEGHPQASEKQLEQYLLRKQELARAQGLNMQIVTQFCFDATPV
LDWEKRLRAAGIRLPINLGVYGLTTPKTLVRYGLACGVGQSLRFMQKQRWKLHRWFTPCN
PKDLVDAIAGSIAETPDTLFHGLHFYPFGAIARTLEWRRNLSCSGTGEPS
>A0A3D9FKJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasphingopyxis lamellibrachiae|TrEMBL
MNLTVDQLHEARRATDDPLFADLAGDAQISFEFFPPKNAKMETTLWDSVKTLEPLNPRFV
SVTYGAGGSTRERTHATVRRIVEETPIQAAAHLTCVDASKAEIEEVIGDYWDAGVRHIVA
LRGDPPRKGDTFEPFRPHPEGYASAAELVAGIKAFKPFEVSVAAYPEVHPEADCPQADLD
NLKRKLDAGATRAITQFFFSAENFFRFRDAVAAAGIDAEIVPGILPVSNVATTQRIAGMC
GAAIPPWMNRLFEGLDELPAARQLIAATVAAEMCRKLYAGGVREFHFYTLNRAELSYAIC
HLLGMRPHGPDQTS
>A0A3G9G3M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asticcacaulis excentricus|TrEMBL
MAPPPAFVQSAIARSVRAGASHLNVSFEFFPPKSAEMEESLWGAIRRLEPLNPSFVSVTY
GAGGSTRERTHRTVKRILDETALKPAAHLTCVEASREEVDEVIREYWNAGVRHIVALRGD
PPGGLQDGQYRPRPDGYQNATELTAAIRRIGDFEVSVGVYPEKHPQSPSLDFDLDVLRQK
VDAGATRGISQFFFEPETFLRFRDAVADAGIQIDLTPGIMPVTNFKGLRKMAAACEAAVP
DWLQELFQGLDDDAETRKLLASAVAVEQVLGLEREGVNHFHFYTLNRAELVYSICRVLGL
RDGQPTAA
>A0A5B0S7T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia graminis f. sp. tritici|TrEMBL
MKISQKLAAAESENRISWSFEYFPPKTDNGLTNLYDRICRMSQLGPIFIDITWGAGGSTS
NLTTEFVKTAHEQFGLETCMHLTCTNMPKSKIDTALKEAYEFGCENILALRGDPPKGSTE
WTATEGGFEHAIDLVRHIRAEYGDHFDIAVAGFPEGHMHSTLSREQQTIYLKEKIEAGAN
FIFTQMFYDVDIFIDWVREIRAAGITVPVIPGLMPIQSWAQFKRVTNFSKTIVPQYFLDK
LEPIQSDDQAVREAGTKLVADMCRKILNSDLGIRILHFYTMNLERGTKMILDELNLNPSR
DITNPLPWKMSLLGKRRSESIRPIFWANRAKSYLSRTETWDEFPNGRWGDSRSPAYGELD
GYGININAATMETLKGLKKFPTSLADLARIFANYCGARFPGEEPVKYLPWSDIPLSEETN
KIEDVLVKINKRGFLTINSQPAVDGAKSSDPVHGWGPRGGYVYQKAYLEFFCCPEKFQSL
TERLEKDPDVTYYAVTKTGDLVTNNTRPGPNAVTWGVFPGKEIVQPTIVELVSFIAWKDE
AFELGHQWAELYKEIAPESARFIHQIMDSWYLVNIVNNDFRKSNDDSEHSALFQFFGPEP
VIVDQDDLPPTTNGLSHPNGLPKTNGSSSPAISEVNGELKNLAI
>A0A0M3HKP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ascaris lumbricoides|TrEMBL
MIECCAGYESIRRIAALSQLTIPESILKALEPIRHDDDAVRSFGIRHAVEMCRRLLNSGT
ATSIHLYTMNREASC
>A9U7N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Physcomitrium patens|TrEMBL
RIAREVAGSAGYVVGAIGSIRGGKRTNVSTAELKKYFEQQIQALLQEGVDGILLETFYDV
EELYLALSIVRKLSPLPVICQFAVEDVARTLDGYTMPEAFRMMQQQGADVIGFNCRTGPN
GIMSAMKTLGGHMSVPMSVYPNAGVADYVDGEYQYGAKPDYFGQMAVKFADLGARIIGGC
CGTTPAHIAAISSALQGYEPQPITYGPIDIAPAPIEIHEHLAPDGDGEGEGGSPNLVDLV
KERHTVIVELDPPRDLDIAKFMKGAQVLKDAGADALTLADNSLAVTRMSNMALGHLVQAE
TGLRPLVHIACRDRNLIGTQSHLMGFDALGIDHVLAVTGDPARFGDLPGSSSVYDLTSFE
IIRMIKQLNEGIAFSGKPLKQKANFVVGAAFNPHGKHLDKA
>D0J903|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blattabacterium sp. subsp. Periplaneta americana (strain BPLAN)|TrEMBL
MKVTDHIDKAKKSLFSFEILPPLRGHDIKDIFSTLDPLMEFNPPFIDVTYHREEFIYVEK
ENGLLQRRTISRRPGTVGICAAIMNKYGIDAVPHLICGGFNRQMTENALIDLNFLGIDNV
LVLRGDPLKSEKSFFSKKDGHQYAVELVEQVKNLNNGKYLDNTFEQKDSPLFDFCIGIAG
YPEKHLEAPNMESDLFFLKKKVEAGANYIVTQMFFDNKKYFSFVKKCRSEGITVPIIPGI
KPISSKKQLNSLPSRFYLNIPHELVKEIEKVKDKKMISHIGIEWAIQQSKELKDSGVEVI
HYYTMDKPENIYKIVQAVY
>A0A2V1A895|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] duobushaemulonis|TrEMBL
MSTVLNKIQALQPGERFCSFEFFPPKTDAGFRNLLARLSRMMALNPLFLTITWGAGGSTS
EKSLDLAATCQKELGVTTVLHLTCTNTNKEIIEDALKRAREAGIKNILALRGDPPRAEEY
WTPNCDFNNAVDLVRYIREQHGDYFCIGVAGYPEGHVEGADASDQDPRKDLPYLIEKVEA
GADYVVTQLFFDVDKFVAYEQLLQETPQLKNIVLIPGLMPITTYRVFIRSTRLSHASVPK
TILEDLNAHANDDDMVKVIGLDVLTKMISEIDARTNGRVRGYHFYTLNLEKAVASIINRS
PVLQNMIPHNQSVQHDDAIASDSDDDLPVVPQKNGRRKSSVNENSVAVPGTAEAKRALVS
KALSKDPKAIVDISTGKGALGKDATWDEFTNGRFGDSNSPAYGEIDGYGPNLKLHSNKEV
EETWGEPKSVSDITKIFVDYLSNKINVLPWADSELSPETALIQEELFELNERGWFTLASQ
PAVNNCSSRDKILGWGPSNGHIFQKSFVEFFIPKKQWHDDLLPRLASQVDDKTITYYCGD
ASGHISSNLPLSIGKNSNSKSAVTWGVFPSKEVLQPTIIDYESFRAWNEEAFLLWLEWAR
CYRKDSASFQLLNDIYNSYYLVSLVHHNFTDEFVLWTTLLSD
>A0A7T4Y7A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp. ISTL7|TrEMBL
MQDRYYSFEFFPPKTPEGREKLRNTRAQLAPLGPKYISVTFGAGGTTQQGTLDAVLEIQR
DGIDAAPHLSCVGSTREGIREILRTYRDNGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFQIEVAAYPEYHPQARSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRALGVDVPIVPGIMPITNYAQLMRFSEMCGAEVPRWVAKRLESFGDDREAIRAFGLDV
VTALCERLLAGGVPGLHFYTLNAAGATKAIWQRLKL
>A0A1G2YBF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium GWF2_50_10|TrEMBL
MQQGPLQKLLSQRVIIGDGAMGTMLYSQGVFVNSCFDELNLSNPVLIKKIHQQYVEAGAD
FIETNTFGANECKLARFGLADKVELINTKAVQIAREAAPSTVLIAGAAGPLDMEIEPYGS
FALQKVKDAFKRQISSLAKAGVDFLILETFVLPEELCIAIEAARSVCDLEIIAQLTVDSQ
QETKYGQRVDEAILTLPLEHVTAVGLNCSVGPSAMLAGLELLLEATDKPVSLQPNAGMPR
QVDGRMVYMCTPEYMAEYAKRFFEKGARIIAGCCGTEPQHIKQMVKAVRALDKAVTAKPK
SPSVLSVGRETSLPPTKSLGQKSKFGHKLASRQKVTTVEIVPPRGVDLTAIYQKAQLCAK
AGVDAINIPDGPRASSRLSPMVAAIKIEQTCGIETIVHVCGRDRNLIGIQADMLGAYAIG
LRNVLAITGDPPKLGEYPDATAVFDLDSIGMVRLIRNLNAGIDLGANRFSPQVELTIGVG
VNPAAVDLKREVERYRAKIDAGAEYAITQPVFDRDCLERFLEITSDCKIPVIAGIWPFAS
FKNAEFMANEVPGVVVPSNILERMRGASDRNDAVKTGIDIAKEMIDSVGDKVAGFAVSAP
FGNVGIALAVLGKSEIT
>A0A7K5CVR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pachyramphus minor|TrEMBL
MVNETQQSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCSNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGIACPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPR
>A0A1Q8WFV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MHDNEPTGPTAAAGGRAGGLSSAETGTARQLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPADGISSGGHEGSARESEAGRCEAAPRVRAVQEQTNPSECVLAH
VLESSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRADDVAGELRH
ADDLVRVIREVEADFFGDGRRHVTIAVAAYPATSDHIEAIEVLAAKQAAGADMAITQVFY
DAADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSTLGSASGAT
LVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDA
VDRGYLQATPGRGPSFLRRGSPGAALSSRHPVQPHTTITKENA
>A0A1G7SJ25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klenkia brasiliensis|TrEMBL
MTYGPCGGVAEDGSCEVAPDPCAFLPLPTVRWPRERESRPGPEPRLLALMRQRPVVVADL
PAVALSRGSLERCTDLVAGRVDAVLLGDHAAARVQFPPAYRAALVQSRGVPVWQGLNCRD
RNRVALEGELAALADLGVGAVHCVTGDHTATGDRPDAQPVFDLDSTQLAAASRAAGLLVS
VGETPHGPPADRRPQRLVEKVRAGAEVCFVDHAGGPAELADFVAAATDAGADVPFVACVA
VATDPGSVAELRRFTGLRLPAGYLAAIESARDPRRAGVAAAVELAEAYLAVPGVRGVDLS
GVAAPGTEPTTAAALAEIGRALG
>A0A4R6KY24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2571|TrEMBL
MANGLPSTRPGGAPTIRELLASGDRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWVAHPEGLNHATELVELIRSLGDFCVGVAAFPDKHPEAASLEADAQVLAA
KAQAGADYAITQMFFGADDYFRLVDRAAALGCEIPVLPGIMPVTNIKQIQRMADLTGMAL
PTAVTDRLLAVEDDPAAVREVGVEIATELCERLLAGGAPGIHFITLNRSTATRQVFRNLT
AAVVS
>A0A171BYM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planomonospora sphaerica|TrEMBL
MTDRPFEIVCEIEPPTRPDLKHVRHQIGTLSRIAGSFLVPDNHIGRATVSSVAVAHEVQA
MGGRSIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPATGNRTSDLTVRSMIEEV
RRLGEDPAFAGSPAFRVGTAAGLRPLPAWKRAADFVFVQVCFSLEALLRWREANPVDVPV
YAGVMVIASENHARRLAAAIPDIDIPADLVERVAADRLAGVGAACEQVLAIRDSGAFDGV
HLIPVSRYREVESRLSGAL
>A0A4U6P8K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. MP9-4|TrEMBL
MTQTDRARHDAEGPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFVSVTY
GAGGSTRERTHNTVARIAKETPLAAAAHLTCVAASKAEIDEVADAYWEAGVRHIVALRGD
PPEAGTAFQPHPDGYKGAAELVEGLRKRHDFEISVAAYPETHPDALSAQSDIDNLKRKID
AGATRAITQFFFEADTFFRFRDTVAAAGIDADVIPGIMPVSNFAAVQRMSAMCNTDVPAW
MGRLFDGLDQHPAARQLVSATLAAELCRNLYMGGVRDFHFYTLNRAELSYAICHLLGLRP
QVTVDA
>A0A0E8XIW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia wautersii|TrEMBL
MERKLSFEMNSAKNEKEMENIFKLIEFTDTLDPIYYTVNTEIGSSVWSDTYRTVIELREK
TDVPLVPHITINNKKEREIMQIIEQYIKAGICEFFVIRGDKHVYDQDNPINYGVELIELI
RRSDKNIGIKTSLYPDFHKETTDVKEEMDWNERKYQLGVNEFISQLTLNTNALDFLSHWV
DKERPFTPSIMPLGNFSFIEKFTSSNSIDYPLWIKKFANSKSNSNEDKENIGIEIIRFLC
REYLNKRERLHVFTLNKVDVMKKIFQ
>A0A512D7G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas aerilata|TrEMBL
MPAPVPARRPGLTHGPAAIDRPTVSFELFPPRTPEATATLWRTVEALARVRPDFMSVTYG
ASGSTRATTRELVRRLLAETHVLPIAHLTCVGATRRDLVTVIEEFLDEGVRTFLALRGDP
PTGAAEWRPHPGGLTRASELVELIREVEHARCGSSASGALRGAAHKLSIAVAAFPTGHPG
PESPEERRARDLQSLVAKQAAGADFAITQVFFDARTYLDLVRDARALGVSIPILAGVFPT
TDPARLLRLEQMTGVTVPADLLGRLLATDDEDERHRIGTRASVDLANAVLDGGAPGLHVY
TFNRHRAALALVEGAGLAEASVAGPSRPLGPPPPIPSVIPHPHDLETQGAP
>A0A0C1DLG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia vulneris|TrEMBL
MRTHSGTAVPFSVEFNPPRDAPAEARLWRAVRQFERMHPAFVSMTYGAGGSTRDRTVRVT
GALAQETTLLPVAHLTAVEHSVAELRSLVGSYADSGIRNILVLRGDPPGDPLGAWQRHPD
GVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLDSDTAFLAAKLRAGAEYSITQMFFD
VEHYLRLRDRVQKFDPIEGAKPIIPELMPITSLRTVARAEELCGRTLPPAVLARLHKAAG
DAPDGNPAAVREAGIEIATEMAQRLIDEGAPCLHFITLNFAKATTEVLTNLGYGVTAAPI
SA
>A0A3M0C4L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenothermus marinus|TrEMBL
MKISEKLKQVNTSISFEFFPPKNEEGEKQLFNTIKDLEKLNPTFVSVTYGAGGSTRDRTR
NIVKKIHEETSLTVMAHLTCIGHTKKELIEILSDYKNIGIQNILALRGDIPLGQEESEIY
KKDGCRFANELVKLIRTEFKDWFSIGVAAYPEGHPESPNLERDILYFKKKVEAGADFAIT
QMFFDNRYFYEYLNLCEKEGINIPIIPGIMPITNFKQIRKFALMCGATIPEDLVKKLEKV
EDKPEEVEKIGIEFATKQCEDLLKHGVKGLHFYTLNKSKATIEIYNNIKHLVK
>A0A1J5S1P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MLFDKIRNRENGIVLYGMVPPKRETPPEKVEEISLRQVQRLQSLKIDGLILYDIHDEQSR
TPEERPFPFIETIDPFFYSNNYLSALCIPKVIYRSVGKYSNSELSRFFAEASPENDLTVL
VGASSNSQEVTFSLSEAYKLKREINRDLLMGGVTIPERHLSKGNEHVRVFDKMFQGCSFF
VSQGVYDLNASKSFLSDYYYYGQEHNVPLVPIIFTLTPCGSLKTLQFMRWLGISIPRWLE
NELTHAKDILQQSVEFSEQCWLELKNFADQKGIPVGCNIESVAVRQAEVEASIELLQRVT
KQ
>A0A8J7H2A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobilitalea sibirica|TrEMBL
MKHRLIMDGSMGTYYSNLINLPGAFSETANLTTPKVIEQIHTEYILAGARMIRTNTFAAN
RAALKIDVKEQRLLVEAACRIAKNAVSEFTTDKNSHMIWIAGDVGPIVEDANSTWEEIFE
EYKLLCDIFIDQGLHGIHFETFPSLKYIEELVPYIKERNKDMFILASFSLNKNGYSGAGI
SASRLMEKVGLIEGIDGCGFNCGVGSGHMYQIFKKVNFPDHKYIFAAPNAGYPEQMQNRM
VFMDNEAYFAKNMRQIAELGTDLLGGCCGTTPAYMKAMIQNIDIDQPSNIRKKNQSQASG
IETVEKPNDFYELFKSKKKVIAVELDPPYDANIDHILECAHILKNSKADIITFADSPLGR
SRVDSILMSTKIAEETGLKVMPHVCCRDRNMISMRASLLGAYIHGIRNLLIVTGDPVPGD
SRVSTTGVFDYNSIRLMEYVKEMNIEHFKTEPFYYGGALNHGRGSIEKVVARMKKKIDAG
AKFFLTQPVYSIEDAERILRIKELVDTKILCGIMPLVSYRNANFIKNEFSGINVPDEIVN
RYRPDMSKEEAELVGASIAREIMEFLEPVADGYYIMLPFNRVSLMEKIMG
>A0A7C0Y8K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosulfidibacter takaii|TrEMBL
VGVAGYPEGHIENPDKEADLRYLKLKVDKGADFIVTQLFFDNRFFFDFLKRAKAIGIKVP
IIPGIMPITNLKQVMRFTQLCGATIPRALLEWLEEGNTPEEVRRRGIEHAHLQCKELVER
GIKALHFYTLNRSRATEEILTRLLGEPEV
>A0A1F8QSH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_57_11|TrEMBL
MTPSKFLDLLDQSPSPLLSDGAMGTMLNARGASFEACFDLLNLSHPALVAEVHREYIESG
SNIIQTNTFGANRYKLSAHGLEGKVAEINRAGVELARRVVAASFKDVLVAGDVGPLGVRL
APFGRVQPEQARQAFAEQIAALASAGVDLIILETFSDLLELSEAVLAARQECELSVVASM
SFTRDDRTLLGDSPARVARVLAASGADVIGVNCSGGPAQIWRILRQMRQAAPAAQLSAMP
NAGWPEQVGGRIMYPANPDYFGEYALAFCEAGARLVGGCCGTTPAHIAAMRLALDSLPQG
CGPSVSELAMPAEVEEALEQAGVASPLAQKLAQGKFVVSVEMDPPRGLSAHKLLAGASLL
AEAGADVINVADSPMARMRMSPWAVCDLIHRQVGVDTTLHFPTRGRNLLRVQGDLLAAHA
LGIRNIFVVMGDPTAIGDYPDAMDNYDLVPSGLIKLIKQSFNLGLDHAGVDIGQPTSFFV
GCALNLAPQDIDQEIKNLQRKVKAGADFLLTQPVFDPLAAATFLQRYADRYGPLDLPVFA
GVLPLYSVRHTTFLHNEVPGISISESTQERIRRAGAEAPWEGVRIALELVEQMKPWARGI
YLMPQFGRYDLAAEIVEKCR
>A0A7X7H1G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistaceae bacterium|TrEMBL
MRDYFEQAKPTMTFEIFPPKGSGDLASIFATVDALASLAPDLISVTYGAGGTSRENTVEI
ASQIQNSYAIPVLAHLTCAGNSIEDVEPVLQVLSKNGVKNILALRGDLAEGETLKDFKYA
SDLIRYIKSRYDFRVFAACYPEKHIEASSMEDDLRCLKEKADCGVDALISQLFFDNELFY
RFRNRARAMGIETPIVAGIMPITSASQISRMVSMCGATVPEKVRKIIKAFGHNSMAMKEA
GIAYATAQIVDLLSTGVDGIHLYTMNQPDIAKRISENIRGILYSLRVKRG
>A0A1J5QCG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MTAVDRPTVSFELFPPRNPDAAPKLWATIQALASARPDFVSVTYGASGATRYTTRALVRR
LLRETSLNPIAHLTCVGVSRAEITQVVEEFLDEGVRSFLALRGDPPVGQPDWHPHPDGLR
TASDLVSLLRTIESRRAAGSPSQKVRGAVRPLSVAVAAFPRGNAGAGSTRDQDIQALLDK
QASGADFAITQVFFDAGCYLDLVAAARDAGVTIPIIPGIIPTTDPARLLRVQELTGVEVP
RDLLAALTAEDDPVARHRVGIRASVELVTRVLDGGAPGVHIYTFNTHQAALDLLEGAHLG
GGAPMAPDVASEPRVQAPPSTFIPSRG
>A0A7X7S3Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MAARLADRSRPLRLFSLTPPRETTPVEDLDRVAALTVERIHGLDLDALVLYDIEDESDRN
PDERPFPFVRCLDPADFHAGHLAAWRQPVIIYRSVGKYEPEVLKQWLADQDAERVATVLV
GASSSSKTVRTRLSEAQSLWRDTGSIVPLGSVAIPERHAQHLDEHERILRKQQAGSSFFV
TQVVYDLTAAKDMVSDYAYACRERGVEPAHTVFTLSVCGSLKTLEFLQWLGVHVPRWLQN
QLAHVEDPLGESYDQCVRTARELAAFCRHLDVPFGFNVESVSIRRVEIEASVRLAAEIRD
LLAE
>F1VXK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacteraceae bacterium IMCC9480|TrEMBL
MTSPDFSIEFFPPKPAEGADKLRATRARMAVLNPKYFSVTFGAGGSTQQGTLDTVLDIRS
EGHQAAPHISCLGSSRARLREILAEYRSHGIERLVALRGDLPSGYGAMDAASGEFRYANE
LVEFIRAESGDWFHVEVGAYPEMHPQARSPSDDMQHFVRKVQAGADAAITQYFYNADAYF
RFVDSARKHGVQVPIVAGVMPITNYTQLMRFSDMCGAEIPRWIRLALASYGDDSESIRAF
GLDVVTAMCERLLVGGAPGLHFYSLNQAAPTMAICQRLDASLV
>A0A3A4K9J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia panacis|TrEMBL
MTFDNVPGRSTLGPDQPPPNVSATPSVVRSLRTHSGRAVPFSVEFNPPRDAAGEARLWRA
VRQFERMHPAFVSMTYGAGGSTADRTVRITGELAEETTLLPVAHLTAVGHSLAELRSLMG
GYADCGIRNILVLRGDPPGDPLGEWHKHPEGVEYAEELVRIVRDLGDFHVGVASFPQGHH
RSPDLESDTRFLVSKLRAGAEYSITQMFFDVDHYLRLRDRVAACDPVEALKPIIPELMPI
TSLRTVARAEELSGRSLPESVLARLRRAAGDGPEEDRAAVRETGIEIATEMGERLIAEGA
PCLHFITLNFAKATGEVLANLGYGVTAAPISA
>A0A2A3FDE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. ACPA4|TrEMBL
MTFDAVRGRSSDGWASRTPSIVDRITSSTGSRIPFSVEFSPPRDAEAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSIDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPDGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
HDTKYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAFDPEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGSQENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTSDVSTDSQASV
>A0A1J5R0R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MDIPNLSFEFFPPKTPEGAVKLRATRQQLYAHRPQFCSVTFGAGGSTQDGTLHTVKEIAE
EGMAAAPHLSCIGASHDSIRNLLRRYRAEGIRRIVALRGDLPSGYGIGGEFHHARDLVAF
IRAETGDWFHIEVAAYPETHPQARTPQDDLRYFAEKMRAGANSAITQYFFNSDAYFRFVD
EAAAIGVDAPVVPGIMPITNASQLLRFSEVCGAEVPRWIRLRLQSFGDDRASILAFGREV
VADLCDQLLAGGAPGLHVYTLNQAAPTLDLLRDLGGR
>A0A1K1LIE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosovibrio sp. Nv17|TrEMBL
MESQKRFVPTFSFEFFPPQTADGMEKLRATCRQLAQLDPKFFSVTFGAGGSTRDRTLEAV
LKIQAEGHAAAPHLSCIGSTRESIRAMLERYREVGIRHIVALRGDLPSGMAQSGEFRYAE
ELVRFIRKEFGSAFHIEVAAYPEYHPQAPSAQDDLLNFRRKVEAGADSAITQYFYNADAY
FNFIDACEAMGIDVPIVPGIMPINKFSQLARFSDTCGAEIPRWIRKKLEGYGDDGASIRA
FGLDVVTDLCDRLLSAGAPGLHFYTLNSAGLTTTIWQRLGL
>A0A1G7VGQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionivibrio dicarboxylicus|TrEMBL
MTTNISIEFFPPQTPEGLEKLRGERAKLAVLKPEFFSVTYGAGGSTRERTFAVVKEIAAE
GYEAAPHLSCIGSTRASIREILDEFQSAGIRRIVALRGDLPSGTAEAGEFRYANELVEFV
RSETGKHFEIEVAAYPEWHPQARFPRDDLANFVRKVKAGADSAITQYFYNADAYFHFVDE
VRRQGVDIPIVPGIMPIVSFSKLARFSDVCGAELPRWMRRKFEGLGDDTEAIRAFGLDLV
TSLCQRLLAGGAPGLHFYSMNQSALTLEICKRLGI
>A0A562WDC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sagamiensis|TrEMBL
MALGLPSVLPSSQPSIGELIRDCQPTFSFEFFPPKTPAGETLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGDPTGEWVPHPEGVHYAEDLVRLIRDSGDFSVGVAAFPYRHPRSPDVASDTDYFVR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILPGVMPVTQLATIARSEQLSGAPF
PPALAERFAKVGDDPEAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWRNLQ
VGARV
>A0A387FX38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium jaguaris|TrEMBL
MSSKTENGQRGIRISFEFFPPKSEEAEVQLWNTVADLTEWQPEFVSVTYGAGGSTKAPTL
SAVRRMIHETPFTTASHLTCVGATREDTHRVIDDFLSAGVRRFVALRGDPPGGVGSAYRP
HPGGYANAAELVSALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGANRALTQF
FFDNDVFERYHDRVRAAGVKIPVVPGIMPIQNLTQLKRFAGACGTSIPSWLDERFDGLDE
HADKRASVAADVAAEQIEDLVRRGINEFHLYTMNRSPLVSAVLERLGIRRKADACEGAAA
>A0A7K3WC57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter deserti|TrEMBL
MTHGPCGGVTGSRGCEVAPLPCPFVELPTVRWTGPPRPAPGPEPHLLALMRQRPVVVADL
PSQALSRVSLQRAAETVAGQVDAVLLGDHGGARVQFPPTHRAAIVQAQGVPVWQGLTCRD
RNRVALEGELAGLADVGVAAVHCVTGDHTDVGDRPDARPVFDLDSTQLAAAAAAAGLLVS
VGETPTGPPARRRPARLAEKVRAGAQVCFVNHAGPAGAVADFVQAATDAGADVPFVACVA
VALDPGSAAELRRFTGLVLPAGYLDAIESARDPRRAGIAAAIALAESYLAVPGVRGVDLS
TVPTPGRELSTAAALAEIGAELT
>A0A5N4DCD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Camelus dromedarius|TrEMBL
PAPRGCGSHAHRSSSTTCSSSTGTPCTPPSSSFTATLDPSAYPLPARIRASRDWPRLCHV
ALSSLGKETGSGCRRVGRGPASHDGGGTASNVTSGRGHVGGGASRRQRGWCPPSGPASPR
QPDTCASPPTXXXXXXAPRPLRWCPQSGQAAATCALSESSATRSRNSAMVNEPRGNGGPN
PRSEGSSSGSESSKESSRCSTPGLDPERHEKLKEKMKRRMESGDKWFSLEFFPPRTAQGA
VNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQ
SREEITGHLHKAKQLGLKNILALRGGRRNREATWRLGETQHCDLNPADPIGDQWEEEEGG
FNYAADLVKHIRGEFGDYFDICVAGGAPLSLLPSLSAGYPKGHPDAESFEADLMHLKEKV
AAGADFIITQLFFEADTFFRFFKACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQ
QIKDVIEPIKDNDAAIRNYGIEQAVSLCRELLESGLVPGLHFYTLNREVATMEVLKRLGM
WIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFG
ELKDYYLFYLKSKSPKEELLKMWGKELTSEESVFEVFVRYLSGEPNQDGYKVSAAGMGVL
PASPRPVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGWGPS
GGYVFQKVWHGSMSVPPWDAPGSLPQAYLEFFTSRETTEALLQVLKKYELRVNYHIVDVK
GENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGKLYEEESP
SRMIIQHIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRAPQNEREMEAP
>A0A8B4YIK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus pentosus|TrEMBL
MNLKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHQSYIQAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAVTAREHADHPVYILGTIGGLAGDTDAAVQR
ATQAEIAANVTEQLTALLATEQLDGILLETYYDLSELLAALKIVKAHTDLPVITNVSMLA
AGVLRNGTSFTDAIVQLHAAGADVIGTNCRLGPYYLAQSFENLAIPADVKLAVYPNSGLP
GTDQDGAIVYDGEPSYFEEYAERFRQLGLSIIGGCCGTTPLHTAATVRGLSSRSLVPHNA
PTHVAQAPTLVTTKSQHRFLHKVATEKTVLVELDPPRDFDTRKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTAIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAV
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TDVSTKSISRKLSYGCDYIITQPVYDLANVDALADALAANQIDVPVFVGVMPLVSRRNAE
FLHHEVHGIRLPKSVLERMQQAELDGNERAVGITIAKELIDGICARFNGVHIVTPFNRFK
TVLELVNYVQQKNLTKVQ
>A0A1A8EE05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius kadleci|TrEMBL
MGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITGHL
AKAKHLGLKNIMALRGDPVGSDWEEEEGGFNYAVDLVKHIRSEFDDYFDVCVAGYPTGHP
EAESYEDDLRHLKEKVDAGADFIITQLFFRADTFLTFVDDCRAIGVTCPILPGIFPIQGY
QSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIHQAVEMCRVLLDSGKVPGLHFYT
LNREVAPTEVLRQLGLWIEDPRRPLPWA
>A0A5N4DC19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Camelus dromedarius|TrEMBL
PAPRGCGSHAHRSSSTTCSSSTGTPCTPPSSSFTATLDPSAYPLPARIRASRDWPRLCHV
ALSSLGKETGSGCRRVGRGPASHDGGGTASNVTSGRGHVGGGASRRQRGWCPPSGPASPR
QPDTCASPPTXXXXXXAPRPLRWCPQSGQAAATCALSESSATRSRNSAMVNEPRGNGGPN
PRSEGSSSGSESSKESSRCSTPGLDPERHEKLKEKMKRRMESGDKWFSLEFFPPRTAQGA
VNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQ
SREEITGHLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYAADLVKHIRGEFGDYFDIC
VAGYPKGHPDAESFEADLMHLKEKVAAGADFIITQLFFEADTFFRFFKACSEMGITCPIL
PGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCRELLESG
LVPGLHFYTLNREVATMEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKS
YIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGKELTSEESVFE
VFVRYLSGEPNQDGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPS
SDPIVGWGPSGGYVFQKAYLEFFTSRETTEALLQVLKKYELRVNYHIVDVKGTAAVCAPG
LLSPPPQGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGK
LYEEESPSRMIIQHIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRAPQNEREMEAP
>A0A142YY07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia caribensis|TrEMBL
MNPIELSFEFFPPKTQEGLDKLRATRAELLPLKPKFVSVTFGAGGSTQQGTLDTVLDMAK
DGLEAAPHLSCIGSSRESLRAILNEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFRIEVAGYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VADLCRRLVEAKVPGLHFYTLNGAGATKAICERLGG
>A0A1C6JBD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Eubacterium sp|TrEMBL
MKLAELFKNKKTVFSFEVFPPKRNNPIETIYHTLDELQDLKPDFISVTYGASGSLADNST
CEIASAIKHRYGIESAAHLTCVNSTKEEVTQVLKQLHENEVENILALRGDLVPDVSPKED
FKHASELITFIKESEYDFGISGACYPEGHLDSRDQIEDILNLKKKVDAGAQHLISQLFFD
NNLFYDFLDKARIAGINVPIEAGIMPVVNKKQIERMVSLCGASLPAKFTKMMSRYETRPE
AMRDAGIAYAVNQIVDLVSQGVDGVHLYTMNNPYIARRISESVKSLF
>A0A483ACZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured SUP05 cluster bacterium|TrEMBL
MQLSFEFFPPRTDQGKQNLREVRQQLSIIKPHYFSTTFGAGGTTQDATLETVLDIQANDG
IPAAPHLSCIDSEKSKILTLLNQYKDAGINRIVALRGDIPSGVRDIGDFHYANELVEFIR
NEFNDHFHIEVAAYPEMHPQAENMKTDITHFVDKINAGADSAITQYFYNADAYFRFVDEV
QNQGVDTLITPGIMPITNYDQLLRFSTMCGAEIPRWIEKRLAGYGDDMQSLRVFGFDVVA
NLCDQLKTQGVENFHFYSMNKSQPSLKLAQSII
>A0A0H3Z067|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKAELRELLNLYKSAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVQTPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQS
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A1F1GSE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC078H07|TrEMBL
MSPRLSASAPLDQISEDTPKHLERTALSFEVIPPRHDADAAKIDRLLATLSAYNPDYIAV
TSSQRSGWLKGTAAFIEKISRDTAMRPLAHLACTAGTEQELIGWIDALVDAGVRGLLALR
GDLPEEGMPEGHLPHADSLVRLIRRWESARVARLAAGRLAVGVACYPNGHAESATPDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTKVLDRLAAATSPEEEQEIGMQITASLAQSVLNAGADGLHIYTHNNPDITTDLL
NRIGVTP
>A0A1F9M4F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYD12_FULL_55_16|TrEMBL
MLVKDILLNNRISFSFEFFPPKDEPGWEYLFANISDLMPLKPAYVSVTYGAGGSTRDRTH
KLIVRIQQETNLTVVSHLTCVGSNRVETGEILRSYAASGIKNILALRGDPPKGQTDFVQP
QDGFAHAADLVSFIKKGFPQMGIGVAGFPEGHPATPNRLLEMDYLKAKVDAGADYIVTQL
FFDNRDFYDFRDRCALAGITVPIIAGLMPITTKSGMVRMAELAAGARIPASLLRGLDRAR
SDEQVEKVGVHWTTEQVRDLLDNEVRGIHFYTLNHSRQALDIYQTLGVEDSLQLGA
>A0A1A8CSG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius kadleci|TrEMBL
MVNQVQRVDGSWLSCKSDSSGTSNSGGESSKESSRCSTPVLDAVRSDRLRDKMRRRMESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEEEEGGFNYAV
DLVKHIRSEFDDYFDVCVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTF
LTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKREESVFEVFTCYITGQLNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDAVVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRV
NYHIVNVHGRNLTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLKSCLWQVLDDMFELLDAPLETLADEMPG
DGSHGDGSHDNGTLAE
>A0A3M2TD41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus sp. HF37|TrEMBL
MSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNKEFMYAVDLVRYIREQH
GNYFCVGVAAYPEGHPSESYQDPQDPARDLPYLIEKVEAGADFIMTQLTYDLDAYTRFEQ
LLRNHESGVFKSIPIIPGLMPIHSHKILTRVTKLSHVQIPPPILERMERLKYDDDSVKQA
GVDILTNIVEGVKKIPCPGPRGFHFYTLNLEKTVSFILENCDLIPEHPDESAVFDGEDMA
PDGPSTTEIISNEGQGRSFAKRRASSINSQPHNRVVVDKSQIQSISNESSKDSTTHEAPA
TSAGMPAMPPNRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVP
ASAARRIWGHPVSHEDVNTLFRRHVSGDLYIVPWSEGGAEEVTGGLNPETNEIRPELLKL
IDGRGWWTLASQPAVNGVRSDHPVFGWGPQREGFVFQKPFVEFFCPSKDYKTILKPMLEK
HGHEQFAWFATNETGEFESSLPAQPDADNTIEMNPDNVNAVTWGVFRGKEIVTPTIIEEV
SFRAWGDEAFRIWDEWRRIFPRGSPTERFLESAKKDVWLVCVVGQQFGAGTEVGSKEEED
ETKFLWRVLVGEE
>A0A0N9HX98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kibdelosporangium phytohabitans|TrEMBL
MTSVLERINVGRATFSVEFMPPRDDADEQILWRSIRELEGLDPAFVSVTYGAGGSRRDRT
IRTTGRVARETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVHNVLALRGDPPGNPMGEWV
KHPQGLSYAEDLVRLVRELGDFCVGVAAFPYGHPRCPDVEMDADRLVQKFRAGADFAVGQ
LCYSAEDFLRLRDRVAAKGGNAPILPGVMPLTTPKMLSKTVELSGAPVPPHIAGRLEPLT
DDPKAFRAEGIDVVTEMCQELLAEGVDVLHFYTFNRAKATKEVLGRLGLMPSRTA
>A0A444WMX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium dauae|TrEMBL
MKVTEHIQNADEKALFSFEILPPLKGQNIQCIFDTIDPLMEFNPPFIDVTYHREEYTYKD
VGNGLLEKKIVKKRPGTVGICAAIQNKYKVDAVPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKAEKNGHRYASELVTQISELNNGIYLDDELENSHTTNFCIGVGAY
PEKHMEAPNFDTDLQFLKQKIDKGADYIVTQMFFDNSKFFDFVAKCRKAGINVPIIPGLK
PLTTKSQLNMIPHRFKVDLPDALVIEILKAKDNEAVKQIGIEWCIQQSKEIITAGIPIVH
YYSMGKSDTVKRVAKEVF
>A0A0J5PE70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructobacillus sp. EFB-N1|TrEMBL
MQSVTDFYQDHRGPVISQELTIKNGLKSACARNQAQYFSLANQGQTDHDWQTLLKTATKV
QLTTKKPVMVHVRAKDVQPDQVKSTFHHLLDLELNNFLLVTGDKLADSNGFSSAQELLVA
TGQTGLAKLSLATTLDVNQVANHGVAWVVNQTLAKDRAGAKVLISQIFFDVDNFLAVQEG
LKMGGSDLILVAGILHYPSQNQLDWVQRVLRLTVPDDWRENPDLASARLVADLTDGQAAG
IHYFANF
>A0A196QNJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. EhN04|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYREHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A154WFV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanibaculum pacificum|TrEMBL
MSGTLSFEFFPPKTPAMEESLWRSIQRLAPLKPDFVSVTYGAGGSTRERTHSTLQRLLAE
TQLVPAAHLTCVNANRDEVDEVAQAYWDAGVRHIVALRGDAPADAAGNFTRYLPHPEGYA
FAVDLVAGLKRIGDFEVSVAGYPERHPESADLSDDLDNLKRKVDAGATRVITQFFFEAET
FCRFVENARKAGITVPIVPGILPVTNFAQVQKFAKACGAAVPDWMGGLFEGLDGDPETRQ
LVSASVAVKLCEKLRDNGVEDFHFYTLNRADLTLAICRMLGLGARVPASVA
>A0A2A4GLD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinivibrio sp. YCSC6|TrEMBL
MSYTHAGHIDALNQNIADLNGDINVSFEFFPPSTPTMEETLWNSVHRLKALKPKFMSVTY
GANSGERDRTHDIVKSIHEQTGIAAAPHLTCIDASEDELRHIARDYWQNGIRDIVALRGD
LPSPEKKPDMYAVDLVRLLKEEHDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQASRFAKVTNVRVPQWMHKQYQ
GLEDDPVTRQMVGASIAIDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPLAAVS
>A0A415JJN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF38-3AC|TrEMBL
MRVDEVFKQAASLGTVPVSFEMFPPKGELTLDTARKVAGSLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCIGRTHADIAAKIDEYRTAGVNNILALRGDLPAGAT
EDDKPASEYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLSLSVEYLKQKQDSGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMSKSQISRMVFMCGASLPSPVIKILAK
YENDPESLRAAGVEYATRQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A8J3K1V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catellatospora chokoriensis|TrEMBL
MSDDSVTARRSLRAMLERAEDGVLLLGITPPRRSVSPEQAAQIAEVTLARLATVDLDGLI
LYDIDDESDRNPQERPFPYLPTMDPVSFHRDHLGSWELPSVVYRCVGKYTEPELADWLGE
VDTDRVLGVFVGASSRDKGVRTGLTQAYALRDRVRADLPLGAVAITERYTRTGDEHLRML
TKQDRGASFFITQVVYDVDATKSLLSDYYYTCAQKGVAPRPVIFTLSVCGSLKTLSFLHW
LGVNVPRWLENALRYSDDPLTESYQQCLVTARELAAFCRRLGVPFGFNVESVSIRKVEIE
ASVELAREVRDLLNG
>A0A1F8MXQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_53_26|TrEMBL
MRTTANLVREAILDPDTFCVTWEQVPGRGAFEMQQEELVENARRAARRGRIHAVSVTDNP
GGNPAISTEILCTEIRKLGIEPLVHLAFRDKNRNECESMLYGLAALGVRNLLLLTGDYPS
SGGFMGRSKPVFDLDSVHGLQLVEMMNAGMEHEAMGKKTTLAPTDFFAGTSVSPFKQSEA
ELVGQYHKLKKKVDAGADFVITQLGYDARKLHEVLTWLKVNGYNTPVMSNIYVLPYGAAK
IMNANQIPGCVVTDKLLEEVAQEAKASDKGRSARLARAAKIYAVAKGMGCAGAHIGGHGL
TYEMVEGIIDKGEELAKDWKTLVAEFDYPQPNGFYFFERDLKTGLNLETPASRPAKTGLS
PVYELSRLAHVTLFNPRSIIFKAFKPVMKRVDSSARIESIFGSMEHLAKVAMFGCMNCGD
CSLFDVAFLCPMSQCPKNQRNGPCGGSHEGWCEVHPDKKCVWVRAYERLKRHKEDNSIGE
YTVPPCNWELMGTPSWINFYLGRDHTAKRLGIPPVPKKPPSVERDKVKSDQKTASS
>A0A7K4F728|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilus sp|TrEMBL
MTIRYEANPPKILPDKNLEELISNFVNKIKLISNNCDSIHLTENVLGHARVSPIKVGKII
KKEIPNLPITVSLRVRDKSKIEIEEFVREAISVGFSGILVLLGDPSQNGQSDSGLIPSQV
VKMLKEKRIDSKIELYLSISNKPNFSKIEKKLEANPKGFITQVVDKVEQVQKLAENLKGY
SLIPIVLYPSEKNEASAKFLGLDFGTYRENFNEFLNQIHQITGDVLITSPSDFLGLNQFL
EKRST
>A0A7C1DV87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSDLKSGSNLEKVLRAGHFAFTGECGPPQGADVEAVRKKAAHLKGCVDAVNITDNQTAVV
RMSSWAASLILLQDGVEPNFQMVCRDRNRLAMQSDILGAYAHGIRNMLCLSGDHQKFGNH
PESKNVFDLDSIQLVNMVKTMRDEGKFLNGQEIETPPKLFIGAASNPFADPFDFRPYRLA
KKVAAGADFVQTQCIYNMEKFREFMKRAVDMGLHEKCYILAGVTPMKSVGMARYMAKQVP
GMDVPDSLIKRLQGAGKGKVAEEGIRFALEQIEEFKAMEGVSGVHLMAIEWEHRVPEISE
RAGMLPRPEL
>A0A653NVQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus altitudinis|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSLDEIKR
SFREQLYILLNEEPDGLLLETYYDIEEAKAVLEIARKETALPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPLLENSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHISAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLIAANELKSAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIREIMAKAGEDKEKQRTEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKEPNIHANYH
>A0A8H7Y2C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psilocybe cubensis|TrEMBL
MKLTDKISARDASNPFFTFEFFPPRTDQGFENLMSRISRLSSLNPLAISVTWGAGGSTKD
RSLELAGLTQHSDLDTILHLTCTNMEIGLIDQVLSAAKDQGIHNILALRGDPPRGEEEWT
ASDPRFTRAVDLVSYIRSIPEYSSWFCVGVAGYPDGHADNPVDEDTEISRLKEKVDAGAD
FIITQLFYDTNHFLLWYRKVRAEGIDVPVIPGIMPIQTYSSFSRVTKLSGARVPESVSAA
LAAISQDDRLVKDYGVKLATETVRRLNFEAGIKGFHFCTLNLEKSVQRVLENLGWAGSPF
STQNKLIIDSSSNPPPSNIDSTLVISPSSATNSATVGLSTLATSEGEAGQGELNNAATWD
DFPNGRFGDFKSPAFGNQDLYGGFGISKNEALALWGNPKEASELTQIFLNYLHSKIPTTP
FSPSPLSPESQMIFSHLENLTKRGWWTVGSQPAVDGTDSSDDVVGWGPRSGYVFQKCFVE
FFCGLKEVEEIVKKIEEKGNGWVHYFAGDYKGEFRTNVPANGRNAVTWGVFPGQEIAQTT
IIEAESFLSWKDEAFSIWSEWASFYRPGSEERKLLEGVRDDRWLVSIVHHDYKNKDALWT
FLLDGH
>S5ZA75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. (strain JF8)|TrEMBL
MGLLDELKQRILVADGAMGTLLYSHGVDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDDVPAMNRAAVKLAKQAANGRAYVLGTIGGLRTLNKSVVPLDEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALNRLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRNQGVRLIGGCCGTTPKHIEAMAKALTDRTPVTEKTVKRRAVPVS
VQADRPTPTPLPELARARRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNVAVGSIVKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLISQFNEGLSYSGKSLGQKTNFSIGAAFNPNVRHLDKAVVRM
EKKIQCGAHYFLTQPIYSEEKIVQMYEATKHLDAPIYVGIMPLTGTRNAEFLHHEVPGIT
LSDEIRARMAACGDDPVQAAREGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAATKERKVVHG
>A0A3D6BZQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MLRIFSEELQDPKNFVVTIELVPGRESFGRTTDSLVGIAKDAFADGRVSAVSITDNPGGN
PSLSPDVLGYEIFKYGLDVIVHFTCRDMNRVGMESRALQLARLGMKNILCLTGDYSGKGF
EGRGAPVFDLDSVLLSRMIKGLTHRLLASGDPEPFYQGCGVSPFKTRKSECIAQYKKLDK
KIAAGAGFVITQLGYDINKFNELIRYHNEKNAHIPVMGSVYLLSPRAAKAMNMGRVPGAF
VSDALYKQVASEWKDPKAGMNAAIERAARLGVVLKGFGYRGIHIGGVHKSFDTVGAILDR
MEEIEDDWPKYLSDFADKEKNAYYCYDQVTQVEETPEPKPGIRDRLTDHYPYSFLSTAHN
LFFDKTNVLAPMYRKFAQFLENHDKTWVLKRCLEDPMKMSMLSCQGCGDCGIQHAGFLCP
ESGCPKHTRNGPCGGSRDGFCEVYKEKRCIWVRAYDRLKHADKLSTFLEDRVPPRNWELN
KTSSWANFHLNRDHQKS
>A0A143DBD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haematospirillum jordaniae|TrEMBL
MHTATDPNTASVQRALQVSFEFFPPKTEKMQESLWACVKRLAPLAPLFVSVTYGAGGSTR
ERTHDTVIRLQKEWGVPAAAHLTCVQATRDDIDAVARDYRDAGIRHIVALRGDPPEGSVE
YVPHPGGYPFAVDLVAGLRRIADFEISVAAYPEVHPAARSARDDLENLRRKIDAGATRAI
TQYFFDADTYRRFVDRARSAGISVPIVPGILPVTNFSQVVKFSRACGTSIPAWLRDRFEG
LDEDPRTRELVAATTAIELCEELQRDGVRHFHFYTLNRADLVFAICHTLGVRPPAFSSP
>A0A523YLR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLERLLEKGEFVVTGELGPPKGPDVDVVKKKAAMLKGNVDAVNITDNQTAIVRMS
SIATAKILIEEGLEPNMQMVARDRNRIAMMSDLFGASAFGIKNMLCLSGDHQSFGNHPEA
KNVFDIDSIQMIYMVKTMRDDHKMICGEEIEGDFKMFIGAASNPFADPFQYRVHRLAKKV
EAGVDFIQTQCIYDMKRFKEFMKQVVDMGLHEKCKILAGVTPLKSVGMARYMAANVSGII
IPEEIIDRLKGAGKGNVATEGIKILCEQMQELKETEGIAGIHLMAIEWEHKVAEIMEKAG
FLPRPTI
>A0A435R917|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.003.02.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A1D7VZC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MSQEVLASLLKSARYEILPTAGVVDRVHEYVVPGRVITVTASTGLTLEATLSTAEQLQAL
GFTAVPHIAARMVQGRTELEEIVDRLTQAGIDRIFVPAGDATPPAGGYAGALDLIIDLAS
MAAPIQHLGVGAYPETHPLIPDDVTVQAMWDKRDYATHLVSNLCFDPGTIATWLARVRAR
GIDLPLILGIAGKVELAKLARVATKIGVGESTRFLRKNTVTFTKMAKPGGYNPRKFLDKL
APVLDNPSMGVAGLHIYTFNQIKDTEIWGRRQLAALGHNDEVPSTS
>A0A1G6G7M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides ovatus|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVEAGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMVPKTFKVDLPEALVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A3N5FKW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MNCKTPSKLEKILAAGHIAVTSECGPPRGSNIEHIVHKAGLIKDHVDAINITDNQTSVTR
LCSLAACIKLKLMGLEPVLQMVTRDRNRIAIQSDILGAAAFDIFNMLCLSGDHQSFGDCA
QGQNVHDLDSMQLLQTVRHMRDEGKFLGGADIDSPPKMFVGAAANPFADPFEIRVPRLAK
KVAAGAEFIQTQCIYNLDKFELWMKMARDRGLHEKVYILAGVTPLKSAGMAKYMKNRVPG
MDVPDDVVKRMAAASKEKQPEEGIKICIESIQRLKEVEGVRGFHIMAIEWEEKVPEIVEN
TGLYPRPKVD
>A0A3A4WM64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MDLKEVLKRKKFIVTSEVQTPIDEEPEALVRNLTPVRGRVDGISVSETELDGVVGDTIKA
CEILQKNRFEAIFQTPTRGKNRLQLQKDLITAHEAGVKNLLVFTEDYRITGDSLQEMMFF
HVDSGKLQSVLASLREGATVEGQRLPFKADFILGSGVESGWGKNVPDLELKEMEAMTEIG
TGYFLTTPVFDLDAFEKFMKKAGTFGIPVVAEVMILRTAGMAQFLNRHLKSGLVPDRIIR
QLAGAPDKQKASIEIFAGIVQALKDLCQGVHIITIGGEDRLRHYLDAAKLK
>A0A3D6C7G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
YNTFDLIKLVKKMNSGLDYNDKEFGGKTDFAVSCTATPVGKKTDAELERMSKKIDAGADF
FQTQVVYDAPKTIDFLKQAKPLGKPLLVGLMPLKSVKMARFMTRNVDGIDVPDEVIHRME
TKGATGIDIACDFIRDIIEFADGIHIMAMGDVAGTNKIIEFTRALLSK
>A0A3D6C5Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MGLIDTFGQKFVITTELGPVKGVNTDVALEKAADYLPLDGINIHDCPMGNLRINAIAMGS
LIQSRLGIDAIPHFTCRDRSLLGTQADLLGAHATGIRNILVTTGDPPKQGPYPSKAVYDY
NTFD
>A0A5Q2MH82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium yanjiei|TrEMBL
MRSEATSLLAALRAPTPTCSFEFFPPKDDEGEAVLWQTIADLEPLSPTFVSVTYGAGGTS
QERTVRITGRIAEQTSMRPVGHLTLVGQTRGEIEAVLKQYATAGVDNVLVLRGDPKGGPR
APWEPCPDGMTYAIELVELAAGMGGFEIGVAAFPEGHPDAESLERDAEVLVAKSAAGAEY
AITQLFFRAEDYFGLVERVRALGCDMPIVPGIMPILNFAQVARMAELSGAEMPSEVLEQI
EPIQDDKAAVRAKGIELATQLCRDLLAGGAPGLHFITLNRSKATREIFEALRADGLV
>A0A1V4MAM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ML8_F2|TrEMBL
MLKLTAVSNLEKAINSGQFVATGELGPPKGADLTEFKENAEGMRNHVVACNITDNQTAIV
RTSSIACGATLVQMGIEPIIQITVRDRNRICIQSDVLGAYALGIKNILCIAGDHQKFGNE
TGSKGVYDIDSIQLLKGLKDMRDEKKFMGGDEVEGDIDYFLGAVENPFADPFEYRVTRLE
KKVRAGAKFIQTQCIFDLDRFERFMELVRERGLHKKIAILGGVTPIKSLGAARYMKNNVS
GITIPDALIDRMKGAEDKKAEGLTIAVETIQRLKEIEGVAGVHIMAIAWEEKVPEIVERA
GIYPPPKV
>A0A1L9QID7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium AO1-B|TrEMBL
MTVLSSRLSRGATQTPITASFEFFPPKSEKMGETLWETVQRLAPLNPSFVSVTYGAGGST
RERTHKTVERILNETDLAPAAHLTCVGSPKAEVDAIVKDYWDLGVRHLVALRGDPLAGIG
AVYEPHPEGYAYATDLVEGIKKIANFDVSVSGYPEKHPESGSWQKEIDNLKRKVDAGADR
IITQYFFDNDLFDDYLDRIAAAGINIPVIPGILPIHNFEQTMVFSAKCGTSIPEWVARRF
AGLQNDPETRKLVGVAIACEQVMDLVDRGLTDFHFYTMNRADLTYAICHMLGMGQQGTEK
VAA
>A0A6I1IBA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. FT14W|TrEMBL
MANHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEEAAPHLSCVGGSRESIRAVLADFKAAGVNRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A023X119|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacter radiotolerans|TrEMBL
MSNGPGSRGFRFDFAERLASGVLVTDGAMGTLLGEHGVGFRHPYDRANLTHAELVERLHG
EYVRAGAQLIETNTFSANRVKLSEYKLDERVAEINREGARLARRAADNEANGRERVPVLG
AVGPLGRPLSPIGSITEDEAQGVFREQVEALLEGGVDAVLLETFTDLRELRLAFEVTREF
GVPVLAYKTFVEDGETLAAGLPVRVAKELSGWGVDVVGSNCTVGPQRMVGIVEQMSDEIG
PVAALPNPGLPQLINGEIHYRRDVGHFTEYGVKLAEAGARLIGGCCGTTPEHIKSLADAL
RDFDASGAAARQAVRNVSVKTRDTGEGPSDIFTEEEARPASEFARRLMDGEFATTVEVDL
PRGNDITEVIEASRRLKERGVNAIDISDGARARLRMGPVAVGRIVQDEVGIEVVAHMCCR
DRNTIGLQSDLLSASALGVMNILAITGDPPLIGDYPEATGVFDTDAIGLVHILSEMNRGR
DLAGNSIGRAPGFLIGAAFNPTADDLPAEVEKVRRKHEAGAHAYWSQPVFEIEDLRRAQE
ALAAADLAEIKVLLGLMPLRSARQAEFLHHEVPGINIPKRVREGLAKLPPEDAPKFGVEV
AQELLVAAKDSVAGAYIMPPASAPDLAGDVVEALGTPVR
>A0A6L7FYY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudooceanicola sp. GBMRC 2024|TrEMBL
MTIPEISFEFFPPKNLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRELTRDAVATLHK
NAGLNVAAHLTCVNATRAETLAVADSFAEAGVTEIVALRGDPPKGEGKFTPCEGGFANSV
ELIEALAATGKFTLRVGAYPERHPDAPDADADVTWLKRKFEAGAAEGLTQFFFEADTFLR
FRDRCVAAGIDKPIVPGILPIENWKGMRRFALNCGANVPAWMDEAFEKAGRDGREDLLAT
SLCTEMCDRLMQEGVEKLHFYTLNKPELTRDVCHALGVTPNGKLEHVA
>A0A8G1ZIC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium cupriresistens|TrEMBL
MPVIHPNWERPPVNMVDGYSLEMTAKDVESLREAAPSIAAETPVAVTFLPGEDFAARIAA
TKLVRSLGFEPMPHFSARRITSTDEFENYLAAAVAEADVRRCFVIAGDPSQPEGPYADSS
ALIGSGAFERAGIRAIGIGGHPEGHPNMTPDQCWSVLLDKCTEIERRGMAPLIVTQFVFD
ADAVLVWLTELRARGIEAPVRIGVPGPAGIKTLMRFAARCGVGASASVLAKYGISITKLL
GTAGPDKLVETFERSLGEEHGRIRLHFYPFGGLEKTVAWINDYARAH
>A0A8H3EY15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gomphillus americanus|TrEMBL
MTKIIDKIKALPRDANYFSLEFFPPKTDVGFSNLQARLARMASAFRPLFVTVTWGAGGST
AGRSLELAELCQRQLGLTTCLHLTCTNMSKKLVDEALETAYEIGIRNILALRGDPPRDHE
YELDGVESEGSEQFVWAVDLIKYIRKQYGDYFCIGVAGYPEGHSDESVPASQDPKHDMPY
LLEKIQAGADFILTQLFFDVDAYIAYERLVREYQNGVMKDVTIIPALMPIQSFSILKRTT
YLSHSRVPQDIMDELERMRGDDEEVKKIGVKVLSSIIEKIKSTPSPQHRGFHFFPLNLEK
VISLILQNTHLLPPIVSEAESSAVIEADLTPEEIKIRRIRRSSGRGRRTSSAHNHVTSDD
RTSSTLEPPSRATTLAITNGIGTLGREATWDDYPNGRFGDARSPAFGEIDGYGPSLHLSP
AAARQKWGAPTVASDISALFHNHIDGKLDQLPWSEGPLSPETCVIRTQLQNMIEKRGWWS
IASQPAANGVCSSDPVFGWGPKSGFVFQKAFVEFWIPAKDWQQVLKPYLISSEIASTVSW
YAASNPHNVSLSLSNGTTTNGTNVHQQCSGAKSESSTPASSADSVTWGVFPGKEIVTPTI
IEQLSFRAWADEAYNIWKEWERCYPLGNQSRNLIRSCSEEYWLVNVIAHDYQDKEALWRI
LMAA
>A7VDU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. L2-50|TrEMBL
MRLKEYIQTKRIIADGAFGTYYMSLYGDGSKPEKGLAISNLPELANITAPERVIGIHTEY
IEAGAQLIRTNTFASNTKSLLSDTEAVKENIRAAVTCAKAAAEKAEHEIYIAGDIGPIPA
EGVPHSDNLTKEYIMIGETFIEQGIDILLFETFPELETILPAIAYLKETHDCTILVHFSV
NQFGYSNTGLSAKRLIADAEACRYIDGTGLNCGVGPGHMKKLIRKISADDATFLSVFPNS
GYPKYLNNRLTFTDNAEYFAEKISEIAESGICIFGGCCGTTPDYIRKIAAGISLDYPVGS
RETVAEVTVSSEKPAYGFMERRVKDPSHKLVAVELVPPLNADDEKLLDAAHILKNAEVDV
VTFPDSPSGRTRADSVLMAEKIRLETGLCVMPHICCRDKNAIAIRSTILGASLNHITNFL
LLTGDPVPVLFRQTTKSVFNFDSVGMMKIVQEMNSDTFSEHPVTYGGAINHNRMNTKAET
ERIRRKMAAGATFFMTQPIFSAEQAEIIRQMKKETGATILVGLMPLVSRKNAVFMKNEMT
GIEIPDSVIDRYREDMNREEGENCGIRLAREFMAMTDDFADGYYFSFPFNRVHMLKKILG
>A0A0Q9RXC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Soil796|TrEMBL
MDIAARIKSGQGDFVIFAVTPPRRSTPTDRLPEIARATVERLEHLDLDGLVLYDIDDESS
RNPEERPFPFSPTVDPAEYRTEHLEQWGTPVIVYRAVGKYQREDLRSWIAEQDPRRTLSV
MVGAASSGSSPSVSLADAQAMSAALNPDLLLGGVAIPERHSRRENEHLRLIAKQEAGCRF
FVTQVVYDLNAAKNLVSDYRYECESRGLVPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLRHAANPLLASLAQATATAVELIDYCRRLGVPFGLNVESVSIRREEIEASVELAGQL
AGHLRK
>A0A2I8QY21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. ASNIH3|TrEMBL
MGFHSARQVEALNQSLADLGGDISVSFEFFPPNSEGMENTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLENDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQA
>A0A4R4VRD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora terrae|TrEMBL
MPFASTEEKVLAHVPRDVVLTVTTTEARGLEPTVDLAVRLGKNGYAAAPHLAARLVRDRA
ELDEIAARLLESGVDRLFVVGGDAAEPAGEFPDAESLLVALAEGGHDFSHIGIAGYPEGH
GTIPDSVIAEALRRKTVHANEIVTQLCFNPATTIDWAGGLHESGITTPIRVGVPGSVNRQ
KLIRVSAGLGLGQSARFLAKQSAMFWRFFLPSGYRPDKLVTGLTDQITSPANAISGFHLF
TFNDLAGTERWRQARLAELS
>A0A3E1KEH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas nasturtii|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVDVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
ASLCQRLIEGGVPALHFYTLNLAKPTTQVLQLLGR
>A0A4R4C154|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. SRS-25|TrEMBL
MKTIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNTAAATRTICERLVM
>A0A1I4VT54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. cf124|TrEMBL
MTGATRPAVGTLERSGTAGPRLPGAPADRERPSFSFEFFPPKTEAGARTLWEAIRRVEAL
SPAFVSVTYGAGGSSRRRTVEVTGRIAAETTLRPVAHLTAVGHSVAELRRIVGQYADAGV
RDVLVLRGDPPGDPRGPWVPHPQGLRHACQLVELVRSLGDFSVGVAAFPERHPRSPDWES
DIRHFVAKCRAGADYAITQMFFHVDDYLRLRDRLTAAGCHVPVIPEIMPATDVRQIRRFA
ALSDAAFPEDLAHRLEAARGDPAEGRRIGVAYATAMASRLLDEGAPGLHYITLNKSTATL
EIHRNVEPVRVAHRPPAPEQGWRATRCASPSQVPSPPTIWPPFPGGSPTS
>A0A558QVV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas solaris|TrEMBL
MTFSLTQLEEARRALDAPLFADLAGDAAVSFEFFPPKTAKMEETLWGAIETLAPLAPQFV
SVTYGAGGSTRERTHATVARIARETDIPAAAHLTCVGASKGEILDVAREYWEAGVRHIVA
LRGDPAEAGMPYASHPEGFRNAADLVAGLRTVAPFEISVAAYPENHPDSADEQADIDNLK
AKIDAGAHRAITQFFFSPEAFFRFRDRAAAAGIEAEIVPGILPVSNVAQTRKFAGLCGAA
IPPWMDRLFEGLDAHPAARQLVAATVSAEMCRRLYAGGVRHFHFYTLNRAELAYAICHLL
GKRPVPVAARETVAA
>A0A3D2JF40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ktedonobacter sp|TrEMBL
HFTTRDRNLMALQSELLGAHALGIRNVLALTGDPLRVGAYPNTTGVWDVDSTGLIRILRN
MNEGHDAAGSSLGAHASFHIGCALNLNMSDEEIHQEIEKYHRKLEAGAHYIMTQPIYDAA
PLERFLQRVGTPPVPLILGCIPLHSSRHAEYLHNEVPGITIPDAVRRQMREAGEHGHEEG
LRLAHELLVQVRSHIQGVYLMPSYGRYDVVGELTHMLRTQKVSL
>A0A6L8B179|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MNTESPTKTNFIDALAERILVCDGAIGTELRQRIKTHLHCVDACNISNEHADTVKDIHQA
YVNAGADVIQTNTYQANRKALSVHGLADKVDEINRAGVLLAHSVVSDIGYIAGSVGQIPF
GSQDTSNIDVEPSTKTIRKLFQEQMDPLVDAGVDLLILETFVSTKQAQIATEQALTYHIP
VVVEISGISGGTVGAGIDVRVFAQELEQLGATAVGVNCRGPHDLVQAMELLAPVINVPLV
VQPNAGNPRVEQGEIAVSYTVNADVFTDYVQKLIKLGANMIGGCCGTTPEFTAKIRQAVG
RSKPIRRLPRIFVLPKSSPTSKTQRENPIKQVFETRERIVSVETRANTFPQLRALLKEAR
VLASIGVDLFDVTDNSGAAVNIGAVGTAFRLQQATHIPTLIHWTTRSRNLISMQSHLLEA
EALGIRGIVALSGDHPKAGPYEAASLVPDVRGAVQLMKLIDRLNQGILADGSSIGDPCGF
YYGGGFTIAEKLDPHIKHLSNKVAAGAKFAYTQPVWTFEDIERSQKAIQHLNIKVLYGIL
PLTSFRSASYLRDNLGLYIPQFIVDKFQDLGDTAGSELGMQLTLDLVKEIRNQDTIPIDG
IYLIPPARLNWKNRRSVITEIVQTYR
>A0A7X3REV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MTNLSRKKDSFIYALAHRILVCDGAIGTELRKRIPAHLQCIDACNISEEYAEKVTATHRA
YIEAGADVIQTNTYQANREALTVHRLSEQVEEINKTGVLLAREAATEASYIAGSVGPIPF
QSFDAAVPATKTVRQIFKQQMDALVDAGVDLLLLETFVSPKQAEVATKQALTYGIPVIVE
ISGVSGGTVGAGLDVRVFAQELEQLGAHAVGINCRGPHDLVEAMERIAPVIKVPIVVQPN
AGNPRVEQGEVAVSYTVEADVFSDYVGKLVELGANMIGGCCGTTPEYTARIQQAIAGREP
IKRESRIFVLPEITVGARSPRPSRPDDNPVQQVFETRERIVSVEMRANTFPQLRAMLKEA
KGLAARGADLFDVTDNSGAAVNIGAIGTAYRLQQATQIPTLIHWTTRSRNLISMQSHLLE
AEALGIRGIVALSGDHPKAGPFEAASLVPDVRGAVQLMKLIARLNHGELADGSSIGDPCG
FYYGGGFTVAENLKPHVKHLANKVAQGASFAYTQPVWTYQDIVRNQKATEHLGIKMLYGI
LPLTSFRSASYLRDNLGLYIPQFIVDKFRDLGDTAAQELGMRLCLELIRDIRNLDECEID
GIYLIPPARMNWKNRASVISEIVRTYR
>A0A2D6S3D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
METWQKPSFRSLLQETSTFVACVELVNSRGIITERGGTRVLKLARELSQHPQIHALCITD
NAGGNAMLSADTMGTXLISRGQEVVIHLSCKDWNRNGLQSQAWKLASEGFDNVLALSGDY
PVSGYKGQASAVFDIDSVGLLKMISEMNTGLEVSVGQNKKKQVLKRTRFFSGAVVNNHKR
YEREVMPQYFKLKKKIENGASFIVNQIGYDARKQDELLKYMNWSGLHVPALCNVYVLSLT
AARFFHANNIPGVTVTDDLLALVVKQADSVDKGKAFFLEFAAKQCAIAKGLGFRGVYLGG
HLKASDYKRVLEIADQFGEDDWQDFAKEICFSQTDEFYFFEPDIATKLSSTEINREYLHS
KHLKASQVSRQKVPLGYKINRTIHDIAFKKGTVGFGLGEKISRAIERKNKGAQKIFHGLE
QTFKIAAFDCQDCGDCSLPDIAFLCPESQCVKNQRNGPCGGTKQGKCEVGEKECIWSLAY
DRLKAYDQEEPMLDGPVVFRNGALKGTSAWINTFLGRDHHGKDKK
>A0A495YZT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MNTAPTETPHNSDNSQQPSFRHLLQETDTFLTCVEVVTSRGTITDSDGERVLELAQKLAD
NPRIHGLSITDNPGGNAMIGPDTLGRDLLSRGQEVIIHLSCKDWNRNGLQSRAWQLASEG
FDNILALSGDYPIDGYRGQASPVFDTDSVGLLKMFTDMNAGMTVGAGRRSQVLERTNFFL
GAVVNNHKRYEREVMPQYFKLKKKIENGAAFIINQIGYDSRKQDELLKYMATHNLDVPVI
GNVYVLSRSAARFFNKGNIPGVTVTDELLDLVEKEGKSKDKGKAFLLEFAAKQCAIAKGL
GYRGVYLGGHLRYTDYQKILKIVDHFGEDDWKGFAKEICFHYPGEFYFFEPEPGTGLSST
EINREYLFSKRAEGLKAAKGEIPLGYKINRTVHDQVFEKGSLGFNIGRRISQAIDGASER
VKKAMHGLEQAVKVTAFDCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTRQGKCEIGE
KDCIWGRAYDRLKAYGEEETMLDGPAIFKDGALNGTSAWGNTFLERDHHAKNNE
>A0A7K3FBL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5477|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSAAWDTDVAHFVD
KCRAGADYAITQMFFQPDSYFRLRDRVAAAGCDTPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A1E5FTW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio splendidus 12E03|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSNEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A3N8P4Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia contaminans|TrEMBL
MKTIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVM
>A0A3N7ZEV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Bp9143|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDNLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDREAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAATATRTICERLSM
>A0A2E3N6M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibacillus sp|TrEMBL
MQAXXDIPQLLRQETPTISFEFFPPKSAEASERLFSTIHELKLLNPSFVSVTYGAGGSTR
DLTHKLVLRIMEETTIPAIPHLTCVNHSRAEISEILSGYADARIPAILALRGDPPDGNID
YDRGKDAFCHASELVDFIQKFNQGASDPRKKFGVGVAGFPEGHPDTQNRLREMEYLRQKV
DSGADYICTQLFFNNYSFLDFRDRCRLAGIHIPIIAGIMPITTRSGMARMADLAAGVQFP
AQLQXMLLGXXXDPVAFEKAGTEYXISQCRELLSEGVDGIHFYTLNRSRATAQIASALDI
XQE
>A0A258LHE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidocella sp. 35-58-6|TrEMBL
MTHSPPRDALERWVTGERVMPLPGRSSTGAPAISFEFFPPKTPALETQLWACVERLATLQ
PRFVSVTYGAGGSTQERTHATVVRLVQETNLVPAAHLTCVGATREEVDDVARRYWEAGVR
HIVALRGDAPAGQTYTPYSGGYAYAADLVAGLKRVADFEITVAAYPEVHPQALSEAADMD
NLKRKLDAGATRAITQVFFENTTFLRFLDKAVAAGITAPIVPGIMPVSNFVQAAKFCTGC
GTSVPDWMADLFDGLEDDAETRRMVAAATAAEQVRFLQANGVDEFHFYTLNRPDLVYAIA
RILGVKPAAV
>A0A0T2ID83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycicoccus sp. Root563|TrEMBL
MALGQPSRLERPAQLTRSIPGMLSSPAPSMSFEFFPPKDDASEAVLWDAIRRLESVRPDF
VSVTYGAGGTNQDRTVRVTERIARETTLTPLAHLTCVGASVAALRQVVGLYAASGVRNIL
ALRGDPPGDPGGQWVPHPEGLNHATDLVGLVKSLGDFTIGVAAFPDVHPASPSFEHDVEV
MVRKADAGASFAITQMVFDAESYLRLRDAVAARRPDLPITPGLMPVTNFKQVARMSQLMG
TPLPETVVSRLEAVSGDPAATREVGVQIATELANRMLGEGAPGLHFITMNRSTATLEVHR
NLGLH
>S6DB77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter pasteurianus 386B|TrEMBL
MSLSRLSVELIPRSAEALAADVATVKAAFPAADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQPGLEEILVVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMQGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLDANIQFAQTVLKELAQEKGKAYLMPVRIKLEQY
LPALLDAVA
>A0A1G6E2P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio sp. YE44|TrEMBL
MLKDMFDRDFSLSFEVFPPKKDDEFENCYKVLDSLSTLNPDFISVTYGAGGSNSKKTVDI
ANYIQNTLGMDAMAHMTCVGSEANDILEVTKALEEVGVNHVLALRGDKPRDMSDEQFERR
IFPHATDLIHFLNENTSLSISASCYPEKHPEAISMDSDIAFMKMKQDMGAEMFISQLFFD
NADYYRFIERTDRAGITVPVVAGIMPITSVKQIGSTVTLAGSSVPKKLADICAKYSEDPE
AMRQAGIEYAINQINDLRKCGMGHIHIYCMNKPKMTAEICEAIK
>A0A3G5HT20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium acidifaciens|TrEMBL
MQHEYRPTAVAPQDRLDSRPDETIAQLLARADRPTISAEFFPPRDDEGAAVLHRSIEQLE
ALHPDFVSVTYGANGSSRERTLDAVRDILASTRLRVMGHLTCTGQSVDELKAVIDGYGEM
GVRHVLAIRGDMPGGPLVPWERHPQGLANATELVELVKSRGEFCVGVGAFPDVHPGSTAE
RDVQVLRDKQTAGAEFAITQLFFRPGAYRRLVDRLRDAGCGLPVIAGMMPVIAIGQIDRF
AELSGAPLPDEMVARLRAVGDDRAAVRGVGTALCAELARELLAGGAPGIQFFTQNRSVAT
LEILGRLAGVSW
>A0A0X3VZ68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL S-1521|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGDWVAHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSTDWESDTRHFID
KCRAGADYAITQMFFDPEEYLRLRDRVEAAGCDTPVIPEMMPVTNVRQLDRLPQLSNAVF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHRRA
>A0A2E5D432|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibacillus sp|TrEMBL
MQATTDISQLLTRGKPTISFEFFPPKSDEASEKLFSTIHELKLLDPSFVSVTYGAGGSTR
ELTHKLVLRIMEEATIPAIPHLTCVNHSRAEISEILSGYADARVPAILALRGDPPEGNLD
YDRTQDAFCYASDLVDFIQNFNQGTNDPQKRFGVGVAGFPEGHPDTQNRLKEMEYLRKKV
DSGADYICTQLFFNNYSFLDFRDRCRIAGIHIPIIAGIMPITTRSGMARMADLAAGVQFP
AHLQHMLLDAKEDPVAFEKAGTEYAISQCRELISEGVDGLHFYTLNRSSATAQIASALDL
GKE
>A0A1X4G4E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cylindrospermopsis raciborskii CENA303|TrEMBL
MQENHTTNYTSNTLTSFREAVQAGEFLITAEVAPPKGGDISHTIAMSATLKGRVHAVNIT
DGSRAVLGMSPLAVCAILWQHGIEPVCQIACRDRNRIGLQADLMGAHALGIRNILALTGD
PVKAGDHPDARAVFDLESVRLLQLITNMNQGLDFNHRTLVDGGLDLFAGAAVDPQSKSWS
GLQSRFERKVQAGAQFFQSQLITDFEKLEKFMDKIASGYNKPVLAGIFLLKSAKNAQFIN
RMVPGVNIPDYIIQRLAKAKYPLEEGMKIASEQVRMAKDLCQGVHIMAVKKEEAIAPILD
LAGVSR
>A0A1Q9JQI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerostipes sp. 494a|TrEMBL
MTIQEYLKHHKLITDGAFGTYYSNKYSTQEIPETANITHPDRVLDIHRSYINAGARLIRT
NTFAANTLLLQTDLQKVKENIRAAVKIANDAIQESEHTVYIAGDIGPIPNYQYAQEQYLE
IAKTFLEEGVDILSFETFADMEQILPVIQKIKHKDLFIMVQFSVNQFGYSNSGLSARRLI
QEASCVDEIDAVGLNCGVGPGHMAQILDKINLDHGKFAIALPNAGYPKLIRNHMQFTDNQ
HYFVLKVQEMAEKGMDIVGGCCGTNPDYIQKLSAILDIAQNPKKTSTAQNKSPEKQMIKH
GFFCNPDGSLKKKKLIAVELAPPANVDDEKIMDAAHILKKSGVDVVTFPDSPSGRTRIDS
VLMAEKVKRETNLNVMPHICCRDKNAIAIRSLLMGAQINDIDNMLVITGDPIPVVIRQTV
KGVFNFDAVGLMNIIKDMNEEIFTNHSIVYGGAINQGRPNLEVEIKRVRRKIDAGAEFFF
TQPVFSKAEADRIHTIKKETGARILCGIMPLISRRNALFMKNEIAGIAVTDEIVNRYPEN
GTREEGESVGISIAKEVISYTEDFVDGYYFSFPFNKVYLLDKIL
>Q1I4X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas entomophila (strain L48)|TrEMBL
MSLLKTTLDANAFACILEFVPKPSAERFATLETLMARTQLCGWPLTVAIGDRVGSALDMS
PLEAFSSLANPVPALLHFSGKDRERRDLLAQLQRMDAAGLDQLLLLTGDRLPGHNPGERP
VRYLESVAALQIVRQARPHWLLAAALNPFKYQEAEGGAQYCKAEKKLAAGADLFILQLGF
DFAKHQEAFDWMQRQPRPKPLMACIMALTEGRAGMLDHVAGVTVTPSMRALLAAETAVSK
AYAKERANHRLALQVIGLKLVGYAGVHLSGIHEVAQFEALEQAIDTLQPQFTSLQDWAPA
WQAAWQEPDLTPVTFHPPGHAWRLGQRQINASNKEKARYHLLSAMHHQLFSRTTALSKAF
GWAVTRPLWTNPTAAHWLHQLERRIKRPMVGCDTCGSCRLEDTLYTCPETCPKGLANGPC
GGTSLDRCEFGDRECVHSAKYRLAVSVGRTDVLTERLIPCVQVESRHRSSWPAWFDTTLA
PAPQVNATPELTE
>A0A329F846|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
NGNDVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEG
RYVYEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPK
VVHTHEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADN
SLASPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPA
RVGDFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAV
KRMERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVP
GITLPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVK
YVREKQEVKEGIN
>A0A2C1M5Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEALKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMAPKFIEQGVRLLGGCCGTTPEHIECMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIN
LPEAIRERMDGHETKEAAIEEGIHISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2C1MT24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELIHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVIPVIEKDTIQRPKVVH
THEKRSKAQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGVYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7K3LZJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytoactinopolyspora mesophila|TrEMBL
MSYEVMPFESTEHDVLAAVPTSIRLTVTTTQKRGLDATLELTERLLDHGYAVAPHLPARL
FIDQAHVRDVVARLREKDVRSVFVIGGDSPTAAGRYADAYSLLQALREADHPFDEVGIGG
YPEGHANIPQEAIELALKQKAPMASHLITQMCFDTRTTVSWARRVAEAGIEVPIRVGMPG
PVNRQKLVRVSAGLGLGQSARFLRKQQSVLWRFLLPGGYDPTKFAKHLGAEVNRCGTGIR
GLHIFTFNELRRTEAWRQKLLALLTGRNEA
>A0A7X7TRQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotogaceae bacterium|TrEMBL
MPDNEFYDHEGPSGQQSPECSILNKRFILETLPPRSTTSDKYLDFCESSVKCGVQVIAIT
DLPMGSSRTSPIAPAHMLVERGIDVLMHFSRTTRNAIRIEGDLIASHMLGIKNILILSGD
DPRIGTYPFSSSVEDFTIYDVFKLTKLLNEKNEDLAGVKVYGKFNFCPGGVFSPHEGDYR
QTLERINGKLANGCKFFISQPVFSQQEILDFLEKAADIRNESNIYVAIMLFETRSQLEYF
SKVPGVFVPKEYFRYESDEALKQFSLKRAILMVEKLARYVDGFYLTSTTKDLETIKAISD
VVLDSYQN
>A0A7G7VQR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnospira indica BM01|TrEMBL
MNRFRTACLNPKEFVITAEVAPPKGGDPTHMIEMARGLKNRVHGVNITDGSRAVLGMSSL
ASCVILQHHGIEPILQVACRDRNRIGLQADLLGAHALGIRNILALTGDPVKAGDHVNAKP
VFDFESVRLLQAINKLNNGMDWNDKKLPHGRTDLFPGAAVDPQSPSFSGLQSRFYRKLKA
GACFFQSQLITDFERLYKFMNQVASDTDKPILAGIFLLKSAKNALFINKYVPGVNIPDHI
IHRLEKSSHPLEEGIKIAAEQVQIARQICRGVHLMAVKREDLIPKILDAANIPPLP
>A0A852RIG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides kongjuensis|TrEMBL
MDVATCIEQGRGDFLLFAITPPRQSTPAERLPEIARATVERLEHLDLDGLVLYDIDDESS
RNPAERPFPFSPTVDPSTYRAEHLGSWQAPVIVYRAVGKYQREELRTWLAEQDDRRTLTV
MVGASSSSTSTPVSLVDAQVLRAEENPRLLLGGVAIPERHSRRGDEHLRLIAKQEAGCRF
FVTQVVYDLNAAKNLVSDYRYACEERGLAPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLRHSTNPLTASFEQAAATAAELAEFCRRLQVPFGLNVESVSIRREEIEASVELAARL
SGLVRSG
>A0A2A8S449|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKILDLLSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRAYGLENQVVQINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALIEECVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQLALHEAGTTQNGN
DVNEILTQLLDYGANVVGLNCQLGPLHMTEALKMISIPKSGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPAHIEGMKRAIANVTPVTEKQIVQRQQVVH
MQTKSASTHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNEGRSILGKTIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKVAAGAEYFLTQPIYDVDLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMGGHETQESAVEEGIRISQELIDAAMKYFNGIYLITPFLKYEITENLVKYVK
EKQEVKEGIN
>A0A387A0A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVADKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAEALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNGGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>U6SR07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalophilus marmarensis DSM 21297|TrEMBL
MNFLEKMKNEVLVGDGAMGTLLYEQGISKCFEELNLSDPNRIIDAHKQYIEAGAVIIQTN
TYAANRLKLEKYELDEKVKIINQEAVKLAREAGPNGIFIVGTVGGLQNFHQEEWTKEEVL
EALEEQIEALLVSNVDGILLETFYDLEELLGAINIVRKQSELPIIANVSLGEIGVLHGGV
SLKEAIGKLENAGADVVGINCRMGPSHMLRSLEDVPLPKRAYLSVYPNASLPEYQDGRLF
YHSNPEYFESMGEQFVNQGVRLLGGCCGTTPEHIRAFSHVAERRTPVEEKWVTPSLKKVT
KKIEFPRSLEPLSDIAKKRRSVIVELDPPKKLSTDKFIKGAKVLKEAGVDAVTLADNSLA
SPRIDNMALAAQIKEDVRPLVHVTCRDRNLIGLQSHLMGLHALGINDVLAVTGDPTKVGD
FPGATSVYDVTSFQLISLMKQLNEGISFSGKDLGQKANFSIAAACNPNVRHMDKAVQRME
KKIESGADFFMTQPMYSEEQIEAFYHETKHLDTPVYVGIMPLTSSRNAEFLHNEVPGIKL
TDSIRSSMASCETKESAQLEGIKIAKSLIDTATQYFNGIYLITPFLRYEITAELTAYIEQ
KSTAKLTH
>A0A0R2NE03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pediococcus argentinicus|TrEMBL
MFPPKTEVGVEHLHQTLENLQGIHPDFISVTLGAGGTGRHDLTVHIADEIQNGLGIPAVA
HIPGIYQTKESVDEILDQLEERGISNVLALRGDRIEGLTPTGVFHHADDLTAYIQQRGGF
EIVGACYPQVHQESVNAVDDIKHLCEKVDAGADHLISQVFFDNQCFYDFQEKAELSGIEV
PIEAGIMPCTNKKQIERIAQVAGVPLPHKYVAMLSRYENNPEALRDAGIAYAVDQIADLV
SQGVDGIHLYTMNNSDTAQRIWDATKSLFSATVK
>A0A523TNW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MTEAQSNGYKSGSRLERILRDGHFAVTGELGPPQSSNGDVIREKAKILLGYCDAANITDN
QTAIVRMSSVGAGTIVVQEGLEPIIQMTCRDRNRLAMQSDLMGAYALGMRNVLCLTGDHQ
SFGNHPTAKNVHDLDSLQLLQMMVGMRDEKLFQCGDEIKGIEPRFFLGAAANPFGDPFEY
RPYRLAKKVEAGADFIQTQLIYNVPRFEEYMEKVHDLGLHEKTYILAGVGPLKSPGMAKY
MRDQVPGLDVPDEIVDRMTTATKGIDKEDKKARREAWRSEGIQITIELIQKLRDIEGVCG
VHVMAIEWEEAVKPIVEGAGLMPRPEVTALPAASTETGE
>A0A1M6T1C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia thermophila|TrEMBL
MSPVSDHEVGAMLRRLVRSFSAEITPRETATLPPLDGLLAPGTSVYLTFLQRTPWDRTVA
AARWVAAAGMRPVPHLAARYVPDRAVLARMLADLTAIGVTDLLLVAGSTEPVGEFHETAQ
ILATGLLEEAGIRRVGLAGHPEGHPDVADDVLDAALLTKAALAREHGLTAHVVTQFGFAA
EPVVAWERRIRAAGIDLPVHVGLPGLTSPVKLLRFGLSCGVGPSLSVLRHQTGGVLKLAT
SAVHHPDAMLLGIAEAVAADPASLISDVHFFPFGALPATAAWAGEIRAGRFAVHDRARLS
VPA
>A0A1N7QEZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium gambrini|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICASIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHGSAMELVHQINDLGRGKYLHNQDEICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEDLINEVENAKNNEAVKQIGIEWAIAQCRELLEFGVPVL
HFYSMGKSDNIKKVAGALF
>A0A3S1BD67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. PAMC 29040|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETADHFHIEVAAYPEMHPQARNFEDDINNFVRKAHAGADSAITQYFFNADSYFR
FVERVRAAGVTIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIQSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1W9PNX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacteraceae bacterium 4484_230|TrEMBL
MIEQLIRKLHNGSYITLETTPGHSPKFSPTIDKIADLELENYVDGFTTTDNPLAKLKYNS
LFAAKMLQDRFSKPVIATISMRDRNRIALQSDLLGANEAGIRTILALTGDPAKISDQPHA
KGVFESDSTLLLDMITCFNSGIDYAGRPLVSKPEAIYPFSVINSFAKNPKTLQKKMSKKI
SHGTQGIITQPVYDTESARLLLDLMEEANRENRDRSDAQLILGIFPITKMRTAQFLAS
>A0A413CNL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF11-11|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>U2ZFU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio proteolyticus NBRC 13287|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDASREELIQIADDYWANGIENIVALRGD
IPAGGGRPEMYASDLVQLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVECYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPGWMARQFD
GLDDDPTTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPR
>A0A7V2QXR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTNLEKILESGRFAVTTEAGPPKGXGAGVIQRKGELLLHCCDAINITDNQTAIVRMS
SLAGCALLKQLGADPVMQIVCRDRNRLSIQSDVLGAVALGVGNILCLSGDHQKFGNHPTA
KNVFDIDSIQLIQTLKKMRDEKKFLCDEDISGEVPLFIGAAANPYADPFEFRVTRLAKKV
KAGADFIQTQAVYDVAKFVKWMEMVTDKGLDKEAYILAGVIPIRSVGMARYMRDYVSGVS
VPDEIVTRMEESKSAKEEGVKIVLEIIEQIKEIPGVHGVHIMAVGWEEIIPEIVERAELL
PRPIL
>A0A4E9F9V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brugia malayi|TrEMBL
MDAVRDDNEGEMSPTSSTDGVVIPRSCSKKWGESRTDWVANGTYVPLRDRIKKRIANGIP
FFSLEFFPPKTTNSVANFFARLDRFREGNPMFVDIAWHFGSDPGNISSETSSSSVAAGCL
DYCGMDTMLHITCCPYTKEQSIRHLEQSKALGLKNILALRGDLPRQDENPVLYKYRALDL
IRWIKEEYNDYFTIACAGYPAGHPEAPSYRADLLYLKAKVDAGADFIISQIIFDGEVFKN
FLRDCREIGITVPIIPGILPIQSYESIRRVAELSQLVIPDSILTSLEPIKNDDDAVRNFG
IWHAVTLCRTLLSNGSATSIHLFTLNREASSREILQQLGLWPRSPMRALPWRLFGESHPV
RCKEDVRPIFWSMRPKSYVFRTREWDEFPNGRWGNSSSPAFNDLKDYYLFYLKGQPTRDE
QLRMYGERLETLADIQKVFVNFITQNINENGVKVSQLPWNEQHDGIRAETSLIKDQLLWC
NSNGFLTINSQPSINGAPSTDPFVGWGKPGGYCYQKAYLEFFTSQANAEVLWSLLPSYSR
LNCHIVNHDATIDWTNTETTMPIAVTWGVFPGSEIAQPTVVDPLSFRVWKDEAFSAWLNW
SSIYAEGTSSRCLLEKIYNEYCLVTLVDNDYPKSTIIFDCLAQLVNR
>A0A7V1W1B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MGGSATSALPDGREQASFSRLHAVLLGGQFAVTAEIGPPRGATLAGIRRRARLLRGWIDA
ANITDGQSAVVRLASWAGCVALLEEGVEPVMQLQCRDRNRIALQADLLGAAAVGIPNVLL
LTGDHQRFGDHPDARGVFDLDSVQLIWTARTMRDHGRLLSGRTLSSAPRWFIGAVENPFA
APQRYRAERLGKKVAAGAQFVQTQFVFDVPAFARWMARVRELGLHERCFILAGVGPVRSL
RALEHMRREVPGLHVPEAVVRRMHAMPEDRVAEEGIALCAEIIQQVRDIPGVAGVHIMAF
GWEEAVPDILTRAGLGQRSQAGTAAVAAAELSHSPRSARGNAPEGEAAGRSPAPSPPSTG
GADGLASAPMSLAQYSRRLAWGAQAARLFRRGAGGAQTDRLDGYGR
>A0A6M8WCB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSTNHTAGEPVFSCEFFPPKTDAGVEKLRRARDELARLDPEFFSVTYGAGGSTRERTLGT
VFEIQQAGLEAAPHISCIGATRDTIRELLDLYSERGIKRLVALRGDMPSGMATPGEFRYA
NELVEFIRSETGARFFIEVAAYPEFHPEAHGAEKDLANFARKVAAGANGAITQYFFNADA
YFRFIDDCRRLQIDIPIVPGIMPITNSSQLIRFSEACGAEIPRWVRKRLEGFGDDRDSIR
TFGLEVVTELCTRLLAGGAPGLHFYTMNQSGPTTAIWQTLGLR
>A0A7C3F8M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTKLERILASGKFAVTAEAGPPKGTSAEAMRKKGELLRHCCDAVNVTDNQTAIVRMS
SLAGCLLLKQQGIEPVMQMVVRDRNRLALQGDVLGAVALGIGNILCLSGDHQKFGNHPGA
KGVFDIDSIQLLQTLRMMRDEHKFISGEDISGEVPVFIGAAANPFADPFEYRVHRLAKKL
KAGADFIQTQAVYDVPRFARWMEMLTERGLDKQVHILAGVIPIRSAGMARYMRDYVPGVN
VPDEIVTRMEKSESPKEEGVKIILEIIEQLKDMPGVHGIHIMAVGWEDIVPDVVAKSGLM
PRPVV
>A0A7V7N0S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTPTNKGPVPFILDQGVPGIHFYTLNRAKATLDVVRALGG
>A0A7X1PH14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTTAPPQAASRQRSRFLEALSLRVIVADGAIGTMLQERGVPIDACLEQVNISRPALVRTL
HREYVEAGAELIQTNTFGANRVRLAAFSLEGRVAEINRRAVQIAREAVALTGRGVFIAGD
VGPLGEAVAPEEAQAAFEEQIGSLAQEHVDLLLIETFSSLEEAMIAIAAARKAAPGTPVV
VEMSFLVNGRTAEGRGARETGEALIEAGADVIGVNCGEGPPQALRLLKELARIPGARLIA
QPNAGKPQLVQRRVVYTATADYIAGYAKRFVRAGALIVGGCCGTSPRHIAAMREALDQKP
APDSVSVEIAPTPLAPEPVVARSFQEKLKTGRFVVSVEVDPPRSQAVVQTIEAARLMREA
GADCVNVGDSPMAEARLSAIAMASLLKEKAGIEPVLHCSTRDRNLMALQSDLLGAHALGI
RSVLCIKGDAHALGSYAKATAIWDLNAFGLLRLLRGFNAGEDAAGKPVRPSTSFFAGAAV
NPSAPDLVEEAKMVRRKAQAGAEFLISQAVFEAEAVERLIERLGPSHPPIIIGVWPVHSL
RQADFLSEYITPVPSWVRDRIEAAGSDAEKAGVEMAQDLLEKLRPLAQGVYLIPSFGRFS
GIAELVVAARELADSRA
>A0A7V1QTB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTAPCPAARPQQRIADLFRAGEPLFSFEFFPPRTDAAARALARTVAELAPLNPAFVSVTY
GAGGSTRALTLETVSRLRAETGITVMAHLTCVGHGRAELHRILADLRRAGVRNLMALRGD
PPRGEAAFVPPADGFAHADELIRFVRAEGFDFCIGAACYPEGHLESEDRAQDLVHLAGKV
AAGAEFLITQLFFDNAFYFDFLRRARAVGITVPILPGIMPITDVAQVQRITRLCGATLPT
RLQLQLERCGTPEEVFQVGLRWAIMQCRELLAEGAPGIHFYTLNRSPATRLILGAIRSA
>A0A7Y5SE70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MRFADRLRSGQFAVALEITPPQRPLQSVLLRRASALGHCADAVNVIQRPGRQSSLDASIS
LLRTGIEPVWHLVTRGASRGDIARDLVSAREAGIGQILVIRGDHATHDLPDTPAIREAIG
LAREALPGALIGATFNQYAPDPGAALRNLLPKLRAGADFIQTQPVFDPQALAPFVQRLRD
ECPGVAFVPMVVPLLSPAAVDGIQRRLGFRLPEQLARRLAGGPESGWEVLSETIAGLVAS
PLADGAAIMTTEMDPPPAVGERIVSALRAAGIDC
>A0A8B7VZX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Castor canadensis|TrEMBL
MRPTQPHSCSGPANIESPGTGGPPGGAEATPGPSLLNLLAGEERGGPLALSTPERTESCC
ARISAETPCLAPSNRNPAMVNEARGSGGPHPRSEGSSSGSESSKDSSRCSTPGLDPERHE
KLRDKMKRRMESGDKWFSLEFFPPRTAHGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGS
DKETSSMMIASTAVNYCGLETILHMTCCRQRREEITSHLQKAKQLGLKNILALRGDPTGD
EWEAEEGGFNYAADLVKHIRSEFGDYFDICVAGYPKGHPEAGSFEDDLKYLKEKVSAGAD
FIITQLFFEADTFFHFVKSCTEMGITCPILPGIFPIQLVKLSKLEVPQQIKDVIEPIKDN
DAAIRNYGIELAVSLCQELLASGQVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWA
VSAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKS
KSPTEELLKMWGEELTSEESVFEVFASYLSGEPNRQGYKVTCLPWNDDPLAPETNLMKEE
LLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLR
KYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFAL
WTEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQIVEDTFELLNRPARNE
QETATP
>A0A0B5FT59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geoalkalibacter subterraneus|TrEMBL
MCAERVVIGDGAMGTLLYERGVSLDANFEHLNLVRPTLVASVHEAYAAVGADLLETNTFG
ANRARLGAIGLQSKVAEINRAGARLARQAAGSTRYVAGSVGPLIGPRGGDAPLEESEKRQ
ILREQMNALAEGGVDLFLLETFSSLADLRLALAVAAEIGLPAVAQLAFLEGGRTRDGIDA
ETAVPVLESAGADLIGANCGSGPRDLLAAVKAMAALTDRPLSAFANSGFPQYHDGRYIYL
ATPEYFASMGREMVAAGATLVGGCCGTTPEHIRALSEAVRGSVPAPRMLPRRTQAASPVE
STHPLCRPTGFLDGWGKRPVVTVEIDPPRGLDCDKVLAAARSLHEAGVDAISLAENPLAR
IRLGNLALASRLQQEVGVPVIAHVTCRDRNLIGLHSDLMGAHLLGLRNILAVTGDPVSLG
GESGATSVFDLNSIGLLELLSALNRGTNLMGADLGGHTEFLLGAAFNPNVRNMEGQILRL
EKKIAAGACFVQTQPVYDAALLDEMLRLTEPLEIPVLVGILPLVSERNAEFLHNEVPGIR
LPDTVRQRMRGKSGPEGVAEGLAVARELIDAGRGRVGGWYLMPPFGKVDIALELIRFIRR
WS
>A0A7C7K6G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTTLAELVAKNSRRPFVVCDVSPPRGGSTQLLNGITNVTPDMFFVAANPGGTVRASSVSV
AQWLETNTKIPALFTMTTRDMNKTAMQTTLLGAHVMGLRNLVVVKGDKFPVSGRCTDVSV
KGFTPTAFIRSVKEMNKRTDFTGQALSEPTDFCIGSTLDISRDWGSEMSLTGNKVRCGSD
FLIAQPNFDPVLARKFLEEYQNDQGAGLTVPVMWGVQIMSKDSISFTHVPDHVIKELALG
NSGYEIALEMIHKYLEIGIKDFYLVPPIFRGGRRDYESAQAVIEDL
>A0A1H3A108|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula vallismortis|TrEMBL
MALGTRAVSDSQGVQTLLTSARFELMPFESFDEEITHLPNDATIAITTSPQLGIEKTVEK
TEQAAAMGYDVVPHVAARYVEDWEQLEAIAERLEQAGITDIFVPGGDREEPAGEYESALD
MLEALAETEYTFEEVGITGYPEGHDFIDDETLAESMAQKAPYATYIVTQLCYDPDAVLEW
VEDIRGRGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDNEYNIRGVHIYTFNQTPDTEQWRHKRLDS
>A0A1V4Y548|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophus sp. PtaB.Bin138|TrEMBL
METLFEASLKDPAVMTVTWELVPGRGAREKAQDSVLLEAEKAARGGKIHAVSLTDNPGGQ
PALMADALAVEIKALGIEPLVHFTCKDKNRSQIESQLYALERWGIRNLIVMSGDYPVSGF
QGRPQPVFDLDPTHVLELIRELNGGLKFPLPKGTGELQPGHFFAGAAVSPFKHTEAELLC
QYYKLKKKIDSGASFIVTQLGYDVRKYHELLLYMKRREIDVPVLGNIFLLSYPVARLMME
NRLPGCVVPDDLLAQLDRERSLPDKGLEARLSRGAKMYALLKGLGFSGVHVGGHLVTCEQ
VEAVIEKGEELSASWESLIPEFQYSTPGAFYYFRKDPYGRLNELIPESRQGSRSSLSERR
LYGISRFFHNLIFEPGTKGFALMRSLAAKLKGSRLEGLLHKLEHLLKTLLYDCRDCGDCA
LVDVAFLCPMSQCPKQQRNGPCGGSFQGWCEVYPGRRRCVYVRAYDRLRGSQQESRLEEI
PVPPCNWDLNSSSGWLNFFLGKDHTAKRLGIEEPSDQSR
>B9DIA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus carnosus (strain TM300)|TrEMBL
MSRFLQTLKENVLVADGAIGTILYSEGIDTCPEAYNITHPKKIEQIHRSYIQAGADVIQT
NTYGANFEKLQTFGLEHQVKDITRAAVRIAKKAANEDTFILGTVGGFKGVKQNELSLSTI
LYHTDIQIDTLIDEGVDALLFETYYDLNELLQVIRATKKKYDIPVIAQLTASNTNYLQDG
TEINEALKQVEAEGADVIGLNCHHGPHHMQQSFTHIELPQHALLSCYPNASLLDFENSSI
KYSDNASYFGKIAKSLVKEGVHLIGGCCGTTPEHIHYIKEAVEGLEPINEKKVIPIRRKS
NHPSIPVQKDNLTTKVKSGPTVIVELDTPKHLDTTKFFVNVTKLDKANVDAITLADNSLA
TVRVSNIAAASIIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKV
GHLPGANNVYDVNSKGLTELAVRFNQGLNIDGGALKTTTNFNIAGAFNPNVRKMEAAVRR
LDKKLDSGMNYFITQPVYTVEKIQEIAEKTAHLDSPFFIGIMPITSYRNAQFLHNEVPGI
TLPEDVLEQFEAVKDDKQKTKELSLRICRKLVDEVTKHFNGLYLITPFEQVDYSLELATY
FKTKTENNQEAII
>A0A7D8IHZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klenkia terrae|TrEMBL
MAVVSRPDAGLPRAGRAQLAAALRDATYEVLPFKTAEDKVLADVPTDVALTVTTTEAKGL
GPTVDLAVRLTAAGYRAAPHLAARLVRDRAHLADLVAQLREAGVDRVFVIGGDAAEPAGD
FTDALGLLEALDEMGRPFSTVGIGGYPEGHGSIADELVERALEAKAEHATQVITQLCFDA
ATTVRWARTAYERGVTLPVRVGIPGAISRQKLIRVSAGLGLGQSARFLKKQQNMFWRFFL
PGGYSPDKLIQQLTPAFGVPGSGLEGLHVFTFNELDTTEAWRQRWLARLP
>A0A1Y2X5X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Daldinia sp. EC12|TrEMBL
MEKITDKIAALPADSNYFSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
ATKSLELAEICQRELNLTTCLHLTCTNMSRKLIDRALEDAKALGIRNILALRGDPPRAAE
YQDPNENPEDAIDETFTYAIDLVRYIKKNHGDYFCIGVAAYPEGHADESHPQGQSLEHDL
PYLVDKTLAGADFLMTQLFFDTNAYDTFERTLREHPSGAFKTIPIIPGLMPIQSYQMIKR
TTKLSHAKIPDAIMSRLDAVKMDDEKVKSVGVDILCEIVEKVKEIKSRTPGPKGFHFYTL
NLEKAVSFIIERSDLIPLGTPIEEEAIEDITSKIPALQVNGSLDHETLPEISRSRRQSNV
SSETRNRVIVSGRPVSHPEYEATSAEASIPADPINSRANTLAISEGEGVLGREATWDDFP
NGRWGDARSPAYGEIDGYGPSLHVSHAQAVSLWGYPTKREDINDLFVRHLEKELSAIPWS
EEEFNEETQMIADKLIQLNRKGWWTVASQPAVNGLRSSDPVFGWGPQQGFVFQKAFVEFF
IPDAEWKVLLEKLQSSEVQDTVCFYAANAAGDFVSSDLTGGLAGEVKESSTNAVTWGVFP
GKEIITPTIIEEVSFRAWSEEAFGIFGEWAQIYGKGSETEKLLEKAKADSWLVNIIHHDF
IDKDALWRLLLE
>A0A523UVR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTRLERILASGKFAVTAEAGPPKGTSAEVIRKKGELLRRCCDAVNVTDNQTAIVRMS
SLAGCLLLRQQGIEPVMQMVVRDRNRLALQGDVLGAVALGINNILCLSGDHQKFGNHPTA
KGVFDIDSIQLIQTLKMLRDEKKFISGEDVSGEVPVFIGAVANPFADPFEYRVSRLAKKV
KAGADFIQTQAVYDVPKFARWMEMLTERGLDKKVHILAGVIPVRSAGMARYMRDYVPGVA
VPDEIVTRMEKADNPKEEGVRIILEIIEQLKDMPGVHGIHIMAVNWEDIVPEIVEKSGLM
PRPVV
>A0A2E5LSA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MPYASNLQKLFDNKDFVITSEVSSPDASTHSTLIERLDHLKHSCDAINATDASGAHCHMS
SMAASKIMIDQGIEPILQISCRDRNRIAIQGDVIGAHALGIRNILCLTGDGVETGDHPEA
KAVFDLDSITLLQTISHIKNTGTFLSGRKLENQPDLFLGAASNPFAPPFDFRPFRLQKKI
EAGCQFIQTQYCFDIPRLKSFMETARDLGLDKQCHILVGVGPLKSAATAEWITKNVPGVV
IPDETIGLLRRTPKESQIQEGKKICIDIINQVRSIEGIAGVHIMAYLLDHLVPEIVSESI
LDKEVKSRKSGN
>A0A2E5Q8G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MGRLAEALKASPFVITGELTPPKGTDLGDLFTKAELLREHVTAFNLTESHAARMAMDPVA
VGHLLIDRGVEPIVQMTSRDKNRLAIQASILGAAALGISNIVFMGGDPPKNGDHPDAKPV
FDLFASQLLEAASALNAGNDLTGNPLKGVPQLTIGAVANPGANDIDTEIDNMKRKADAGA
EFFQTQAVYDTEAFGRFMDRAKPDKTVLAGIIPIKSVKMARYMNDRIPGVDIPQQLIDRI
DSAGDDQAQITEISIEIASTTVRALRSMTGGVHVMAIGWEDKVPAILDRSSA
>A0A0Q9NBR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Soil761|TrEMBL
MSPPSLIDAHPNLSDTAPVALSYELFPPRSPAAAETLWTTIRELEATEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAAIVGELLDTGVRGILALRGDLPKD
ASAPATGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEEHDVEVLL
AKQRSGADFAITQVFFETRQYADLLTRARRAGVTIPIIPGVMPLTSLRRLNRLGQLTGVE
PAPELMARLAAADSDLERLHIGVDATVDLANAALDAGAPGIHIYTFNEHQSALEVLDKLA
LPRRSRPGTRRESIARSQLAS
>A0A2E1E2K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKKYSLEILPKQVSNIGKLNTDFFADVYITHIPGSSLDDLVSAASTILDAGFNPIPHIPA
RSFPSANVLKNTLTTLKRIGVKDLLTIGGSIKSPEGPYDSTISMYRSGVFDQLEFEQLRI
AGHPEGNPDDSTPLKSLEGKLTWLRDNAISTAIVTQFCFSHEITNRWISHIKNILEKLFI
TDVEIHIGVAGPAKITTLIKYAKLCGVSASAEFLKKQGLDLAKVVKLSPSKIIDQLNGHD
QIHFFPFGGLEEVSSWISEQISSTEGAEL
>A0A523QTB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MVSRFRDTLNSGKFVITSEVAPPKGTNIDKMLHHIELLKDKVDAINVTDHQSSVMRFPSI
GGCLAIKEQGGEPILQMTCRDRNRLALQAELLLAHTRGINNVLCLTGDAVPVGDHKEAKG
VFDFDSVQLLSAIRSMESGQDMGGNSLDGSVEFCAGAIVTPEAQPIEPQLIKFEKKVEAG
AEFFQTQAIYDLENFGKFMHYARQFPVKILAGIVLLSSARMAKYMNENVPGIFVPKELID
ELANVPKEDMLAKGIEIAGRMIASLKKDAIADGVHIMAISKEEVVPDILAAAGL
>A0A523UII1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKTKSNLERVLELGQFAITSEIGPPQSADPEVIRRKARLLKGHVDAFNVTDGQTAVVRMA
SWAACLIGKEEGLDPIIQMTCRDRNRIALQMDVLGAAALGINNVLCLTGDHQKFGNHPEA
KSVFDLDSIQLIQVVKNMRDEKRFQCGDEMALEPHFFIGAAANPFADPFEFRVTRLAKKV
AAGADFIQTQIVYNVDKFAEWMKRARDRGLHEKVKILAGVAPVKSVGAARYMKTRVPGMD
VPDNVIERLRGVPKEQVPKEGIKLCVDIINQVSQIEGVAGIHLMAIEWEEVVPEIVEAAG
LLPRPKFA
>A0A127FAW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steroidobacter denitrificans|TrEMBL
MSVEYVKERIARAADGLYGRPAVSFEFFPPNNEQMEHTLWQSLQRLIPLQPRFVSVTYGA
DGSTRERTHDIVTRIQQTTSLTAAPHLTCVGASREEVLDIAHNYWEHGIRHIVALRGDPP
QGASVYTPHPGGFPYALDLVKGLKSVADFEISVAAYPETHPEASSPAFDLDYLKAKIDAG
AQRAITQFFFDPELFLRFRDRCAAAGISAAIVPGILPITRFPQMQRMAQRCGASVPDWLV
HRFDGLDEDADTRRLIAAAFAIEQVQALQRHGVEEFHFYTLNRSELTYAICHALDVRPVA
MQAVSA
>L1MZ24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella saccharolytica F0055|TrEMBL
MKVTDFIEHSNTRRYRFSFEVLPPLKGNGTSALFATIDKLNEFDPCYINITTHNSEYVYR
ELENGQFSRERIRRRPGTIAIAAALQQKYSIPVIPHIICSGATIEQIEYELLDLQFLGIS
NLLLLRGDKARDDKHFMPTPDGHAHTTELIAQVNRFNEGFFADGSEMKHPGERFEYGVAC
YPEKHEEAPNIEMDIAYLKQKQDMGAAYAVTQLFFDNARYFSFVQKAREAGVTIPLIPGI
KPFAKLSQLTVVPKTFHCDLPEELAKEVLKCRNDEDAKALGIEWAVQQCKQLYAAGISNI
HFYTVSAVSSVCEVARRLL
>A0A2E0CN63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MLSDKQTISFEFFPPRREEGIPDVVXKMKMLSAYTPDFISVTYGAGGSTQGFTEELSRIA
KADLNLEVMSHITCVGQTTEEIDHILSRLKSSNIDNIIGLRGDPPKGSDKFIPTVGGFQY
ASELINHINNKFEFCVAAAAYPESHTESTSIDTDIEHLKEKVDMGVDFLITQLFFDNDYY
FNFVERARKAGIQIPIIPALLPILNASQIRRFTTLCGASIPEQLNNKLTKIEDDDDQVIQ
LGIEYASQQAENLLSNKVPGVHFYVLNKNYSVQKILKNLNLVPH
>A0A432SP85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp|TrEMBL
MRDQNKIALQSTLLGANYLDVRLFLSLTGDHAKHSDQPDTKNVMEGRSSLFMDMIKCFNN
GIDYAGKEFKSKPKPIYSIAVSNSYAKNFNNLKKRLVSKLNSGVKAIITQPVFDLENAKN
LLNLFEEAKEEAKYCDKDATLILGFFPTFKEWSEANTLESSVLLHEHINPDFTNLSLLHL
IPYETFYTRDDQMIETGGANPVTDIYSAYDFMVDYEAARVVSADHIGVELEFMHHLCEAQ
IKAQKEDDLSAVDALKNVQKEFLNKHLLQWAPLYLINMTYEARTPYYYDIAQTTLEFMLS
DNEHLTQGTPLQ
>A0A424N2V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED1|TrEMBL
MKQHLSFEFSAPRNPEETARLLKVHNKLKVFSPDFFSVTYGAGGSTKEGTKHAVLDIQRL
GSRVAPHLSFGGDKPEKIDELLREYQKAGVKRVVALRGDMPSGQITKMTFARELIEFIRK
STGSYFHIDIAAYPETHPDSASVESDIKFFKNKVDAGANSAITQYFYNADAYFRYMDNCA
SCNINIPIVPGIMPITNYKGIVRFSKNCGAEIPRWMLKQLESYQDQPNSLKAFGLEVVTE
LCEKLLDGGAPGLHFYTLNQALPSASILRNLNS
>A0A396FLI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF36-3AT|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A3B8VXP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAKIPDLANNGSSSLKIICDFSPPRGGTPSLIGDLDGLNPDIVSVAYNPGKSVRVNPVAA
AAWIKANTKQDVVFTLATRDMNKVAIQSLLLGAQLLGLQNIVIVEGDGLSNRDRERFKAV
YDFQPTSLIESVRDMNEGKDFRGLKLRVATDFSVGATIDMGRPSDSEIPLAIRKAQTGAK
FFLAQAEFDPSVIARFRADFESHFDKGHAPPVFYGVQILA
>A0A1B3PEV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. RAC01|TrEMBL
MNAANAQGTGFPVSFEFFPPKTPEGADKLRVARQQLYALQPDFCSVTYGAGGSTQEGTFA
TVREILAEGVSAASHFSCIGATRQSVREQLATLKAMGVRRLVALRGDLPSGYGAGGEFHY
ASDLVAFIRAETGNDFHIEVAAYPEVHPQARSPESDLQAYVAKVQAGADAAITQYFYNSD
AYFRFVEDAQRLGADVPVVPGIMPIASSTQLMRFSDACGAEIPRWIRLRLQAFGDDTVSI
KAFGLDVVTDLCDQLRVAGVPALHFYTMNQSAATLEICRRLGI
>A0A2G2PCD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp|TrEMBL
MFDKLIDKLKNDTYITLETTPAHSPVFSPIIEKIADLGLDKMVDGFSTTDNPLAKLKYNS
LFAAKMLQDRFDKPVLATMSMRDRNKIALQSDLLGANEVDIRAILALTGDPATMSDQPHT
KGVFEADSSMLLDIISCFNSGMNYAGRPFTHKPKEIYPFAVVNSFSKNPKTIQKKIIKKI
KHGAIGIITQPVYDLENAKRLLELSDDANKEYSPDNNKAELILGIFPITKLRTAQFLSAH
VPGIHVPDTWIEKLRYANEISAQEEYKVGFELSKNLFDNIKDIHPKIHLMTANQFQLAHD
ILK
>A0A524AJJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAPSFREVLKSDKFIITSEIGPPKGTNIEKMLHHIDLLKDKVDALNVTDHQSSVMRFPSI
GGCLAIKEKGGEPILQVTCRDRNRLSLQAELLFAYTRGIRNVLCLTGDAVLVGDHKEAKG
VFDLDSAQLLKTIRQMEAGKDLGGNELDGAVEFCAGAIVTPEANPIEPQLIKFEKKIEAG
AEFFQTQAIYDLDKFAKFMEYARQFPVKILAGIILLVSARMAKYMTENVPGVSVPQNLID
ELAAAPKGEAINKGIEIAGRMITTLEKESICDGVHVMAIGREEVVPDILKAAGLAT
>N9QZS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 64.7|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHNVAGIVITPHMLRALAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVKT
KNELVPELAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDLCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A4R4D3Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. 12DCB1|TrEMBL
MENTFRKAIQDNNEFIVTWELVPGRGSKEVSQEKALQLAEQAAKGKKVHAVSLTDNPGGS
VGINPEGIGREIKSLGIDAIIHVACKDKNRTQLESQLFSLERSGLHNLLVLTGDYDPGNF
FGRPKPVFDLDSTQLLAFITKMNGGLELPTVRGIHKLQPTHLFAGAAVSPFKATEAEQML
QYTKLKKKIENGAKFIIPQVGYDVRKYHELYQFVKHNNLPGCLMGNIYLLTYGAAKAMSM
NKVPGCIVTDKLVAELEQEKQSSDKGVAAMLDRAAKLFAILKGMGYKGVHLGGHNTTYEQ
VEYIIDRGNELTANWQDYIREFDYPQKNGFYVYAKDEKTGLNTDQKSNDYNNYEKSFDLN
YKMSRVVHKMMFEPNKGMFGFMRGFCHAIKDSALEKPFHGIEHLAKSCMYNCQDCGDCAL
IDVAYVCPMGNCPKNQRNGPCEGSYNGWCEVYPDKQKCIWVKAYYRLKDYSEEEKLNSYH
VSPYNWEKQHTSGWINFFEGQDHSAERLGIRPRTKSKEKE
>A0A8E3LVB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas yindakuii|TrEMBL
MIPLSFEFYPPKTDEQREQLDRTARRLKAHAPEYVSCTFGAGGSTLSYTPETVRRLRQEH
GFEAAPHLSCVGGTREEIRELLKLYRAIGCRRLVALRGDMPSGMGHAGELRHAADLVAFI
RAETGDHFHIEVACYPETHPQADDAHVDLRHFKAKVDAGANGAITQYFYNADAYFQFVDD
AHRLGVDVPIVPGIMPIANFSQLRRFSEACGAEIPRWIARRMQGYGDDADAIREFGADLV
ARLCRRLIEGGAPGLHFYALNLARPSQAVLARLELAEDRPSLPPPA
>N9P684|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 64.7|TrEMBL
MLNFFQHLEHYKFCILVEYLTSSKTQHVAQDIAGFSAFIAIADRVHSDHDMAPLEASQHY
SKSSDKVLHFSGKDRDIQDFELFLDQAKSANIKNLLLLTGDKLKEHSYGGDESGRTRYLE
SVNAVMVAKRRGGFHLGVAFNPFKYAEAERDAQYLKLHKKMKAGADFIITQLGYDMDALK
QVKAFLNRHHYQQKILACVMPLSFARANFMVKNKVAGIVITPYMLGVLAQEKQDGLSDRV
HLRCALQILMCKHLGFAGVHLSACYKPEEQMLLESYIEQYRHLDLNALEALWNSLWQVKT
GKEFMPELPYYSRQPTSSQLIKYQQLHFMHEALFESKIAKGIGRFIFKASFWEHTPAAKA
LLKTEFISKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPLEVRGTSSWKNWYTEA
>A0A352HD15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp|TrEMBL
ETLWQSVETLAPLGPRFASVTYGAGGSTRERTHQQVVRIQNEARIPAAAHLTCVEATREE
VDEVARHYWDEGIRHIVALRGDAPDGQSQYAPHPGGYANAVELIAGLKRVADFEISVAAY
PEVHPDSPDRQADLDNLKAKFDAGATRAITQFFFDPQCFFDFRDRAAAAGIDGEIVPGIM
PVLSFAAVRRMSGLCGTAIPPWMEGLFDGLDDRPAARQLVSATIAAELCRRLYAGGVRQF
HFYTLNRAELSYAICHMLGLRAKAGR
>A4CYD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. (strain WH7805)|TrEMBL
MNSALQRSLEAGSLTLTAEVMPPRGGDPSETLAMAECLRGRVHAINVTDGSRAVMRMCSL
AVCRLLIDAGLEPVLQVAGRDRNRIGLQADLLGAHALGIRNVLCLTGDPVRAGDQSSVRS
VHELESVRLLQQVSAFNRGEDPVKDRLADGPTNLFAGTAADPHCASWSGLSRRLTRKREA
GARFVQTQMVMDPRSLERFCRDLADPLELPVLAGVFLLKSARNARFINRVVPGACIPNHL
IDRLDQADDPMDEGIAIAAEQVRQFSGIAQGVHLMAVKAEQRIPEVLDRAGVSLPVL
>A0A432G0U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR324 cluster bacterium|TrEMBL
MKVLFGESDSFESNMTIETTDDLQDNLEQQTKWSMEILPHNFADVSLIPDFINEVYITMI
PGAACWETIQTAQQIKAVGKHAVPHIAARSFAGVEELSACLSGLQEAGIERALLIGGGNS
QPAGDFSCVMDLLKTGLLAKYGINAFDFAGHPEGNPDDPNSEFHLLEKLRWTAEREISAR
IVTQWSLDAKKTNNWISDLREKGVSNPIHIGVPGPSTIKTLMRFAKVCGVKASTKVLRKQ
GLSLSKLMFVNKPDKIISGLRGYDQLHLYPFGGIEKSAAWLTEWQTNVSFE
>A0A2D8MJ69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp|TrEMBL
MSPTLDQMREAQRALETPLFSGLPGDIEVSFEFFPPKTEKMSETLWESVKTLEPLDPRFV
SVTYGAGGSTRERTHEAVRRIVGETNIPAAAHLTCVQATREEVDDVAREYWAEGVRHIVA
LRGDAPDGADGYSPHPGGYENAADLIAGLKRIADFEISVAAYPEVHPDSLDRQSDLDNLK
RKFDAGATRAITQFFFEPECFFDFRDKAATAGIAGEIVPGIMPVLSFAAVQRMSGLCGTA
IPDWMEGLFRGLDERPEARQLVSATIAAELCRRLYAGGVRKFHFYTLNRAELSYAICHML
GLRPQGDEL
>A0A0R2T2E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. BACL8 MAG-120531-bin13|TrEMBL
MKITQHIAAAKGKTLFSFEIVPPVKGGNIQELYNNIDPLMAFNPPFIDVTTSREEFVYLK
KEGLLEKKLTRMRPGTVGICASIKHKYGVDTVPHVLCGGFTKEETEYLLVDCQYLGIENV
MALRGDAMAGQRYFEPTPGGHTYAKELVGQIKDLGTGKYLHEEIESAHSSSFCIGVAGYP
EKHMEAPSLQQDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVAAAKEMGIDVPIIPGIKP
IAVEKHLQLLPQVFSLDLPQDLIDAVSDAKDKAAVRQVGIEWAIAQSKELLAAGVPVLHY
YSMGKSSNIEAIAAEVF
>A0A1H3TCK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. NFIX28|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLSQYKAAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A3D2LIE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp|TrEMBL
MNETLWQSVETLAPLGPRFASVTYGAGGSTRERTHQQVVRIQNEARIPAAAHLTCVEATR
EEVDEVARHYWDEGIRHIVALRGDAPDGQSQYAPHPGGYANAVELIAGLKKVADFEISVA
AYPEVHPDSPDRQADLDNLKAKFDAGATRAITQFFFDPQCFFDFRDRAAAAGIDGEIVPG
IMPVLSFAAVRRMSGLCGTAIPPWMEGLFDGLDDRPAARQLVSATIAAELCRRLYAGGVR
QFHFYTLNRAELSYAICHMLGLRAKAGR
>A0A085TZF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioclava atlantica|TrEMBL
MTTPKVSFEFFPPQTLDASFRLWETAQVLAPLKPEFVSVTYGAGGTTRKLTHEAVGAIHK
NYGLNVAAHLTCVEATRAETMEIVNSYAEVGVTEIVALRGDPPKGQGKFTPHPEGFASSV
ELIEALAEDGRFTIRAGAYPEPHPDAADIHADVRFLKRKVEAGASSAITQFFFEAETFFR
FRDACEKEGIEAKIIPGILPIQSWKGAKNFALRCGTSIPAWVEEAFEAAIRDDREQLLAT
ALCTELCDKLIEGGVEDLHFYTLNRPGLTRDVCHALGVTPEAVLENVA
>A0A1G4K0M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea mirantina|TrEMBL
MRISHKLQQRQDRDGSAKEPTFSFEFFVPKTSQGVQNLYDRMDRMYQTHPQFIDITWNAG
GRLSQLSTDLVATSQSVLGLETCMHLTCTNMPVELIDEALQKAYDSGCQNILALRGDPPV
NTNKWTACEGGFSYARDLVRYIRKKYGDHFDIGVAAYPEGHPEETDGRSLIGFLKEKIDA
GADFIITQMFYDGDLFIDWCRDVRAAGISVPIIPGIMPITSYASFMRRVNWCQIHVPEEF
LTRLEPIKENDQLVREHGTELMAKMCQKLIDSGYVTHLHMYTMNLEKASLMILDKLGLLP
KEAEEVNLPNVPLPWRKSLNPQRRNESVRPIFWQRRPYSYVARTSQWAADEFPNGRFGDS
SSPAFGDLDLCGSGLIRQTPTRSLELWSTPTTLQDVANLIIAYLEGKLKCLPWSDTPLNH
EVDSILQPLIELNKNSIVTVNSQPRVNGASSTDSVVGWGPSNGFVYQKEYLEFLLPKSKL
KEFVQNIGDDSPLTYFAVDAADELYSNHPDDTAANAVTWGIFPGREVEQPTIVEKVSFLA
WKEEFFHILDEWKLNFQENNKSDSAELLQDLIDNYFLVNIVDNDFVSGKDRIFELLRGLH
>R6C1V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri CAG:164|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHAHATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDEDAKQLGIEWTTAQVQNLFEHGYNNVH
FFTVSAVDSVKQIAKILF
>F8LIH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius (strain CCHSS3)|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHGATHSLFKHHSQVSAL
>A0A1U9QZN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces niveus|TrEMBL
MALGTASTRTDHARTVRDLLATGKLSYSFEFWAPKTEKGERNLWNALRRVEAVAPNFVSV
TYGAGGSTRAGTVKATQQIASDTTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVKHPEGVTYAADLVRLIKESGDFCVGVAAFPEMHPRSPDWESDIRHFVA
KCRAGADYAITQMFFDPEDYLRLRDKVSAAGCDTPIIPEIMPVTNVRQIERFSQLSNASL
PPALKERILSAAEDPAAVRSIGIEYATEFCATLRAEGVPGLHFITLNNSTATLEIYENLG
LHEQS
>F6I5I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vitis vinifera|TrEMBL
MKVIEKIRDAATEEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGST
ADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHGQD
KFVQIQGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDVILNGVATSEAYQSDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALAILMNL
GLIEESKISRPFPWRRPTNVFRVKEDVRPIFWANRPRSYISRTIGWDQYPHGRWSDSCNP
SYGGLTDYQFMRPRARDKKLQDEWVVPLKSIEDVQERFIKFCLGKLKSSPWSELDGLQPE
SKIINELLGNINSKGFLTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSREKLN
ALVDKCKGHTSLTYMAVNKEGTWMSNVGPGEVNAVTWGVFPAREIIQPTVVDPSSFMVWK
DEAFEIWSRGWALLYPEDDPSRKLLEEVQNSHFLVSLVDNDYINGDLFAIFMEF
>A0A838SKP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidothermales bacterium|TrEMBL
MTDSITAEKGAPLSSRARDHRQRQTLEAALRQARYEVLPLDGTAAQVLEHVPKDVSVTVT
ASPRRGLDATLALSETLARDGYRVVPHLAARLVVDDAHLRETLQRIDEVGIADVFLVSGD
GEPVGDFRDSLGLLTAIHRHRSAGLVQHLQRVGVTGYPEGHPLVPDEQLTEALRAKQPMS
TYMVSQLCFDARAVSAWVRRMRQSGISLPLLPGVAGVVEQRKLLRVAQRIGVGQSARFLR
KHRGIGRLLVPGGYRPDRLVRALAADLADQTGGMAGLHVYTFGAVAATEDWRRTALERLA
GSTDDG
>A0A6P1T8R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbulbifer hydrolyticus|TrEMBL
MSDLRISFEFFPPKTEQGREKLYDTREQLQAFNPEFFSLTYGAGGTTRDTTANIVTGLRR
DGISIAPHLSFGGDNEETVLGLLERYKEAGVDRIVALRGDIPSGMGSVAQLVYANELVAF
IRRHTGDHFHLEVAAYPEIHPEAESYDDDIRFLKGKFEAGASSALTQYFYNPDAYFYFLD
QCEKAGIDAPIYPGIMPITNFANLARFSRNCGAEIPRWLKYRMESFRDPEDVKKLGLEIV
TDLCETLLDGGAPGLHFYTMNSVDPTASILKALDLKQEA
>A0A2S7YSD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. T11011-6|TrEMBL
MTLREKHQQGKFTITVELDPPKSSSAQKVFDQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKDIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNSGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNGA
HFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A2S0IEY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter spanius|TrEMBL
MSESNSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVTKVKAGADAAITQYFFNADAYF
DFVDRARAKGVNVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGVHFYTLNSSEAPLAIWKELTV
>A0A1E8CM72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudohongiella acticola|TrEMBL
MEIVNTDARFSFEFFPPRTEVGVEKLKVVHSELAALRPDFFSVTYGAGGSTKDGTRQTVT
RINETGSDVAPHLSFGGSTRDEILALLESYQALGINRLVALRGDIPSGTGTASQYYYANE
LIEFVRETTGDHFHIEVACYPEIHPQSDSYDSDIEFFKRKVEAGANSAITQYFYNQDAYF
YFLDSCAKAGIDIPIVPGIMPITNFTNLQRFSNSCGAEIPRWMRQRLQSYGDDSDSIREF
GIEVVQSLCEDLLAGGAPGLHFYSMNQTDPVRQIWQQLNLR
>A0A395MHZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium flagelliforme|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKSIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFENTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVNELINKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAVYPEWEATGLEAGVRAEAINSRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGNPKTRRDINDLFVKHIQGELSAIPWSE
EELLAESSTIKPHLLDLNGKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PSNEWETLRAKLVSSELQDYVCFYASNAHGDYVSSDIGGHVNGSTEGNPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNLIHHDY
VNKDALWEVLSS
>A0A2H6J802|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Bbin12|TrEMBL
MESQKRHNPVYSFEFFPPKTPEGVEKLRRVRARLAVLGPRFFSVTFGAGGSTRERTFETV
AEIQRESGIEAAPHLSCIEATREGVRAILSRYRDEGIRHIVALRGDLPSGSGTGGPREFR
YAADLVAFIRAETGRHFFIEVAAYPEVHPQARGARADLLNFQRKVEAGADGAITQYFYNA
DAYLRFVDECEARGLDLPIVPGIMPITNHNRLAHFSDACGAEIPRWIRKRLEDFGDDRDS
IRAFGTEVVSDLCRRLLEAGAPGLHFYTLNQAAPSLAIWENLGLGRIDTAGSPSAHRP
>A0A0L6WYE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Termitomyces sp. J132|TrEMBL
MKITDKITSQITPNPFFTFEFFPPRTDQGFENLISRISRLCILNPLAVSITWGAGGSTRE
RSLELTSLTQLEYGVDTVLHITCTNMERGSVNDALQAAKANKIQNILALRGDPPRGKEEW
IPIDPNFQHAIDLVKFVRSTPEFSDHFCVGVAAYPDGHPDSHLDPDTELNYLKEKVDAGA
DFIVTQLFYDVDRFLEWVKMVRAKGITVPIIPGIMPIQTYSSFLRLVKLCGIRVPQYVMG
ALAPINHNHQYILFLITKHDDQLVKDYGIKLAAEMIERITKQNVVPCFHFCTLNLEKSVQ
RVLEILGWTGTTSPLHNRLIAETAGNVIHPPASVDGTEFMVTPITATNTAAFGLASLPAS
ETEAGRGELNNAASWDEFPNGRFGDYKSPAFGDQDRWGGPAMRNDEVSQWRHPKTLDDLT
QLFLDHLHSRIATTPFSQTALSPESILILGHLEKLTKRGWWTVGSQPAVDSASSADEVFG
WGPRSGYVFQKGFVEFFCTVEDVDAIERRVEERGEGWVHWFAGDVKGECRGNVPEDARNA
VTWGVFPGQEIVQTTIIEKESFISWKEEAFSIWADWASFYRPGSPERTLLESVRNERWLV
SIVHHDYKNVDSLWTFLFDEP
>A0A7X5Y4C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas kaistensis|TrEMBL
MSSAPVPFPAAEPPPLFAHARGDIDVSFEFFPPKTDPMNESLWRSIQMLEPLNPRFVSVT
YGAGGSTRERTHQTVARIVRETGLAAAAHLTCVDASKAEIDDIARAYWDAGVRHIVALRG
DPPEEGRDYAPHPQGYANAADLVAGLTRIAPFEISVACYPEVHPQADCPDSDLDNLKRKI
DAGATRAISQFFFSADNFFRFRDRAAAAGIDAQIVPGILPVSNVAQTRKFAGLCGAEIPA
WMDAMFEGLDALPAARQLIAATVAAELCGQLYAGGIRHFHFYTLNRAELAYAICHLLGVR
APCEAAEAIK
>A0A8D4V4F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas koyamae|TrEMBL
MNISFEIVPRSLAAFDEQYAFVQTLSGGINIINVPDIQRFDTRSWQLATRIDRDKYRFIP
HFRAIDFKIESGELFRIIEEYGLDSVLLVTGDPPEGLKRAFYNTDVVDLIRAVRSRFPEL
NIYAGFDPHRQGLQDECDYIWRKADAGATGFFSQPFYDPRMVEIYAEHMQGLETYIGISP
ITTQASQNYWEVKNRVKFPKSFRPDYDWNVEFANNLIATAAETGLHVYFMPIRIDLAKYF
QRIRFDTAQ
>A0A3Q9TI53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. Arc7-R13|TrEMBL
MTDIPPVDFDRWQPSYDPPPPGHVSGSRLERVLRQGHFAVTAELNPPDSADPADVFAAAR
PLARVADAINATDASGANCHMSSIGISALLTRAGIGTVYQISCRDRNRIAIQGDVLGAAA
MGVRNVLCLTGDGVGLGDQPGARPVFDLDSISLLRTIRTMRDDGMFLSGRRITSPPRMFL
GAAENPCIAPLDWRPDRLAKKVEAGADFIQTNYIFDVPTFARFMARVRDLGLNRRVFILA
GVGPLASARAARWMRSNVPGVHIPDAVIARMERAADPGEEGKRLCIELIQQIRAIAGVSG
VHVMAYRREHLVSEIIAQSGVRDGRPAD
>A0A0D7KHI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. E194|TrEMBL
MKNFREALHEQIIIGDGAMGTYLYQLGYPVGISYEILNVTDPDVIRNIHKQYVDAGSGLL
ETNTFTANREKLYRHGKEHLVKDINRAAVRLAREAAGNQAYVIGALGSIRAGKRENVHTN
QVIRDYHEQMSAMLEEGVDGIMFETFYDLEEMRLALQVVRELDQDVPVICQFAVEESRRT
KDGKSLLEAFRVLRDDGADVVGLNCHMGPNGVLRALEGVQGRIDLPLSAFPNAGLPDYVD
GRYNFAASAEYMAQSAVKFVQMGARIVGGCCGTTPEHVAAIVEALRDVEVPKLPVQPVES
IIIEEESESMLWHDGAACYDGCDHGHDAEESIVDMVRSRHTVIVELDPPRDLDVSKFMKG
AQVLKEAGVDALTLADNSLAVTRMSNLALGYMALDKVGIRPLVHIACRDRNLIGTQSHMM
GLHALGIDHVLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNSGLAFSGKPLKQKAK
FVVGGAFNPNVKHLDKAIARLERKIEAGADYIMTQPVYDKELIVRISEATKHLNVPVFIG
IMPLASGRNAEYLHNEVPGIQLSDEVRSRMSGLEGEAGRKEGVVIAKELLDVALTHFKGI
YFMTPFMFYEMTAELTQYVWEKAERQADPLYRLT
>A0A1G5NJW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas psychrotolerans|TrEMBL
MASPARQGGAAHERDAVKPSLSFEFFPCKTEAGHEKLIATARQLASHGPEFFSCTYGAGG
STRDGTYRTVRQLNDEVGVPTAPHLSCVGDSKAKLRELLQQYREAGINRIVALRGDLPSG
MGLSGGGELRYASDLVAFIREETGDHFHIEVAAYPETHPQARSFTDDVRNFVYKMQAGAD
RAVTQYFFNADCYFHFVERVRKLGVEAPVIPGIMPITNYSKLARFSDACGAELPRWLRKQ
LEAYGDDTQSIQAFGEEVMTALCERLLEGGAPGVHFYTLNQAEPCIAIWRNLGF
>A0A430RYI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus|TrEMBL
MKIRDLLKARKGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRERS
VLWAKRILGLKLNALAHLTVAGQSRKEVAEVLDRFVEAGVENILALRGDPPQGERVFRPH
PQGFRYASELVAHIRTRYGEGLSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRMGIEIPILPGIMPITSYPQLRRFTEVCGASIPGPLLSKLERHQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNRSPATRRVLERLGFKPA
>E9DS87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium acridum (strain CQMa 102)|TrEMBL
MDKITDKVAALPADREYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSKRLVDKALEDAKALGIRNILALRGDPPRKEE
YGDAEDSEDDGQEDFTWAIDLVKYIRRKYGDYFCIGVAAYPEGHSDESHPQEQSLEHDLP
YLVDKVQAGADFIMTQLFFDISAYDHFEKTLREHPSGVFKTIPILPGLMPIQSYQMIKRT
TKLSHAKMPPAIMDRLDAVRGDDEKVKLVGVDIVSELIDQIRSIKSRTPGRRGFHFYTLN
LEKAVSFIVERTGLIHRGSENEEALIDDGTLAPPAIQVNGTRASTHSRTSRRHSSVGSDP
YNRVIVAGQPPTHPEWEATGQEAGVPAESINSRANTLAISEGEGVLGREATWDDFPNGRF
GDSRSPAYGEIDGYGVSLHVSVNQAVTLWGCPTSRQDVNNVFVRHIKGEIPAIPWSEEGL
SPESSTIQSRLVEMNSKGWLTVASQPAVNGIPSSDRTFGWGPVNGFVFQKAFAEFFLPSA
DWHMLAEKLKGSDYFDSVCFYAANAKGDFVSSDISGGASTRTGAASTNAVTWGVFPGKEI
VTPTIIEEVSFKAWSEEAFGLWGEWAKVYGRGSESEKVLSGIRSDYWLVNIIHHDFIDGE
ALWKLLLG
>A0A177N0M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas koyamae|TrEMBL
MNISFEIVPRSLAAFDEQYAFVQTLSGGINIINVPDIQRFDTRSWQLATRIDRDKYRFIP
HFRAIDFKIESGELFRIIEEYGLDSVLLVTGDPPEGLKRAFYNTDVVDLIRAVRSRFPEL
NIYAGFDPHRQGLQDECDYIWRKADAGATGFFSQPFYDPRMVEIYAEHMQGLETYIGISP
ITTQASQNYWEVKNRVKFPKSFRPDYDWNVEFANNLIATAAETGLHVYFMPIRIDLGKYF
QRINIGTAK
>A0A430V3T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus|TrEMBL
MKIRDLLKAQEGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRDRS
VLWAKRILDLGLNALAHLTVAGQSQGEVAGVLDRFVEAGVENILALRGDPPQGERVFRPH
PQGFRYAMELVAFIRSRYGEGVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRMGIEIPILPGIMPITSYTQLRRFTEVCGASIPGPLLSRLERYQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNRSPATRRVLERLGFKPT
>A0A5P9D3B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labrenzia sp. THAF82|TrEMBL
MTEQRLLANGRLPASTEMSPKQVIEKTELLASIPTGTQVYVTDLGNASEDTIVAAARTLT
SHKLTPVPHMAARRYPSYEAFERRIHRLTQEAGVTEVLAIAGEAEKSGPLTSSVSLLETG
LFDKLGIKKIAVAGHPEGAPDISPDVIREFLNRKHELAAQSDAEFRIVTQFGFDPHRVSL
WLDELRDWGNLFPVHIGVAGPAKMTTLLKYAAFAGVENSLNFLKKRGGAVVSMLSGYDPD
TMVEPLENRVVSQPSCQLVQIHVYPFGGVQKTADWLHNRGSWSFQSPSSTLTANESA
>A0A177NWF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas koyamae|TrEMBL
MNISFEIVPRSLAAFDEQYAFVQGLGNGINIINIPDIQRFDTRSWELATRIDRGKYRFVP
HFRAIDFKIESGELYRIIEQYQLDSVLLVTGDPPEGLKRAFYNTDVVDLIRATHQRFPEL
NIYAGFDPHRHGLRDECDYIQRKADAGATGLFSQPFYDSRMVEIYAEQVRGLETYIGISP
ITTKASMNYWEVKNQVKFPADFRPDYDWNVAFANQLIASATIADLHVYFMPIRIDLQKYF
ERIDLPR
>A0A0Q8A7T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. Root157|TrEMBL
MIVNQRDENPAGPHLPLERLPGHTSLGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAINPFAPPYDFRPFRLGKKIAAGAQFVQSQYCFDVQMFRTYMQRVRDLGYTEKVFILC
GVGPLASAKTAKWIRSNVPGIRIPDAVLKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREARDDDRMVADRLDQILNEDLTETQVDMVK
SAH
>A0A231NRR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacterium sp. MES1|TrEMBL
MVISFEISPIQSIQKIQSQKKKIDQLCSFNPNYISCSISGIKDVSFERNLEMCRLLKLDK
RTIPMTHFAIGDKKKKELTDRLKTYVSIGIEHYFVIRGDSKYHSQRNDAFPNSFSFIKTI
KKLNPDMHVSVAGYPETHILADSVKTDIKHLKLKQEFGADKIITQICFDGYAIANWLDLC
QKNDIHLPVDISILPVTNKNRILQLSFANGISIPKELSKIIGRYGDDPQDFKKAGIDYTI
KQIDALKKLGINGFHFLGGNNTSTISEVLTMASLANNN
>A0A519T368|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp|TrEMBL
MKVTEHLARAEGKTLFSFEVLPPRKGENIHTLFSNIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRKRPGTVGICAAIKNRFDVDTVPHLICGGFAKEETENALIDLHFLGIDN
VLALRGDPIKSEGQFQAHPDGHRYACDLIGQVSELNHGRYHDHDEQYQPAGAEPVLCTDF
CIGTAGYPEKHFEAPNFGSDIRFLKEKVDRGADYIVTQMFFDNEEFFKFEKLCRAAGITV
PIIPGLKPLTTKAQLTALPRAFFLSIPEALSEAIHQAKDNAAAREVGIEWCLNQSRELMA
HGVPCLHYYSMGKAEA
>A0A327RCG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olleya aquimaris|TrEMBL
MKVTEHIKNANGNTQFSFEILPPLKGQHIQSIFDNIDPLMEFKPPFIDVTYHREEYVYKD
LGNGLLKKQVVKKRPGTVGICAAIQNKYNVDAIPHILCGGFTKEDTENFLIDLDFLDIDN
VMALRGDAVKTETYFRSEKEGHSYASDLVTQISQLNNGVYLDDDLQNCSVTDFCIGVAAY
PEKHMEAPSLDSDIHFLKKKIKNGAEYIVTQMFFDNQKYFDFVKKCREEGITVPIIPGLK
PIATKKQLNLIPHRFHVDLPEALILEIIKCKDNKAIREVGIEWCIAQSKELKAAGIPVLH
YYSMGKSDNIQTIASQVF
>A0A429BTY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea sp. WAC 01424|TrEMBL
MALGRPSILPDRVPTVRELLAAGGRSFSFEFFPPKTDEGERQLWKAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERLAHDTTLTPVAHFTAVNHSVRELRHLIGRFADAGVRNILAVR
GDPPGDPGADWVQHPEGVLYAEELVRLIRQAGEFCVGVAAFPYKHPRSASVESDTEYFVR
KCRAGADYAITQMFFQADDYLRLRDRVAAQGCETPIIPCIMPVTQMSTIARSEQLSGAPF
PPDVAARFEAVADDPAAVRALGIDHGAELCQRLLDEGAPGIHFITFNRSSASREVFQRLT
PVAATA
>A0A4S1EEH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium 429|TrEMBL
MEFFPPRDIAAQEKLVRTAKTLQGLNPAYVSVTFGAGGSTRSGTVGAVDLLQNLGFDVAP
HLSCVGSTRDELLAILDDYRERGINRIVALRGDLPSGMGGDAGELRYASDLVRLIREHSG
DHFNIEVAGYPEMHPQAISMETDLQHFIHKVQQGANSAITQYFFSPHAYFDFVQRVREKG
LDIPIVPGIMPITNSSQLLRFSNMCGAEIPRWLRLRLADFGDDRASIRAFGVDVIGRLCQ
DLLDGGAPGIHFYTLNGADASMAILPKLTFK
>A0A2T4UY41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter caricis DSM 15933|TrEMBL
MTRARFEIIPTADIAERARRAFPDPSAVVLTVTSLPKHGLERTLDAAIELAALGFGVVPH
LAARTVEGRPALERALGRLGDSGIGEAFVVSGDAKKASGTYSTSLELLRDALEIMPALAV
GIAGYPEGHPHLSDDSILKHLRERAPYIRSIVTQMCFDVDAVARYADSLRAEVIDAELWA
GIPGPVERAKLLSLGAKIGVGSSLGFLTRSSSVAGGLLRGRRFDPTAFVGRLEAAAGDRL
HGLHVYTFNELDGLASFGS
>A0A0Q8AF78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. Root157|TrEMBL
MTITAHPIHRLFETYALEITGKDIAEIGEARATIAPSTPINIAFLGNESHDQRINAATVI
RQCGFLPVPIISSRRLKSKDDRDALLSGLVRAAHIERVILVGGDPSSPAGPYRDSLDLIA
SNILDDHGIRHVGIVGYPEGHPKIVEAALWDALARKVELLRGAGRTVEITTQYGFDAEAV
IVWIERVRALGIDAPIRIGVPGPADVRRLLRFAVQFGVGTSAAIAHKYGFSLANLLSKVG
PGRFLAQLGKRLAADDLGTIRLHFYPFGGIAPTVDWIARQKEAHRPAALA
>A0A1N6IP75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas cryotolerans ATCC 49181|TrEMBL
MESQKQFTPTFSFELFPPQTPEGVEKLRATRKQLAQFNPKFFSVTFGAGGSTRDRTLETV
LEIQAEGHVAAPHLSCIGSTQQNIRAVLEKYRLSGIQHIVALRGDLPSGMAQAGEFRYAS
ELVAFIRKEFGSTFHIDVAAYPEYHPQARSAQEDIKNFKRKIEAGADSVITQYFYNADAY
FHFVKTCEAAGIKIPIVPGIMPINKFLQLVRFSDSCGAEIPRWIRKKLEGYGDDSASIHA
FGLDVVTDLCERLLKAGAPGLHFYTLNSAKFVATIWQRLNIK
>A0A4J2FBH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVNAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A7U7J4E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Contendobacter odensis Run_B_J11|TrEMBL
MPQSNWPQTFSCEFFPPNTDEGMRKLFAAREELMRMQPAFFSVTYGAGGSTRERTFEAIQ
AIQTHSGVDAAPHLTCVASTRSGIREILDHYRAQGIHRIVALRGDLPSGMREFGEFRYAN
ELVEFIRAETGDYFHIEVAAYPEFHPQALSPERDLLNFQRKVEAGANSAITQYFYNPESY
FRLVDDCQRLGLDLPIVPGIMPITNYTQLARFSDACGAEIPRWIRRRLEGFGEDRDAIRA
FGLDVVTDLCQRLLAGGAPGLHFYTMNQAGTTLAIGERLGLTTD
>A0A3P3VY40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gulosibacter macacae|TrEMBL
MSIPFSFELFPPRTAQVAERMPDVARALGALGPEFISVTFGAGGSSRDASLGVLEMVRDL
GGARPLAHLTCVGSSFAEAAEVIAEFVDHGIVDFLALRGDPPQGMDEADDFLGDLRSAAE
LAQLIRGVRIARTPCELQTVGPRLDRWQVRRPSDGLLAVAAYPNGHPQAKSIEQDYDTLL
AKEAAGANLAITQLFFEADDYLSFVEGARAYGVTMPILPGIMSITSIARLERMAALAGEA
VPEKWRRALEGCRSDGARRELGIAQATAMCHDLLDGGAPGLHVYTHNRVDEPIELLCRVG
AVDRTLVAA
>A0A3M8G2K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella sp|TrEMBL
MKVTDHIKNANGKTLFSFEILPPLKGQHIDSIFNNIDPLMEFKPPFIDVTYHREEYIYKE
LDNGLLKKQVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKSETYFKPEKEGHQYAGELVSQIQNLNAGKYLDEELLNSSKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKNGAKYIVTQMFFDNSKFFKFVEKCRAEGIDVPIIPGLK
PIATKKQLNLIPHRFKVDLPQDLILEVIKCKDNYQVRQVGIEWCINQSKELVKEKAPFLH
YYSMGKGDNIKAIASQVF
>A0A2S4UZR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia striiformis|TrEMBL
MKKVVELIECLGDDEVYFTFEYFPPKTIDGLSNLYARIQRMANLKPSCAHVTWGASGSTS
DTSLEIAAMVQDQLSIPACLHLTCTNIQRSHLDQTLSQAKESGIVNILALRGDPPRGTEN
WIPTDQQFQHAIDLVKYIRKEHQTHFCIGVAAYPEGTNDFDQDQELDYLKQKVDAGADFI
VTQLFYDVDFFLNWVKACRKLGINVPIIPGIMPIQSYEGFRRLTALCKTKIPDSIHAKLI
PIKGDDQAVRDFGVELSMQMIKLLQVNGFKSFHLCTLNLERSITRLVSQLGWAPGRGNKQ
CQSLLGPGAKMGTADIVQGGLSVGWDEFPNGRFGDQRSPAFGLREGYSSSLTSAFSHLTT
DVHALWGTPTSLEDITNIFCAFTQGKLHSTPWSEEPLALETTSITPFLAKLNQNGWWTVG
SQPAIDGVDSLDSVVGFGPEGGRVYQKAFVEFFIPKSHLEGLLSAVGEYNKDHPEGVAQL
RYYAGNCNQDQIRTNMALGETNAVTWGVFRGAEVVTTTLIEAQSFKTWKKQAFDIWNDWA
ESFESGSANQRLLNEIEDSYWLCSMINHDFKQADHLWSFLIDHQQRLLAEQS
>A0A4U2LA97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puteibacter caeruleilacunae|TrEMBL
MKVIDIINNTDKTVFSFELLPPLKGQDASKLHRTIESLLEYDPKFINITTHRDVVEYKEQ
SDGIVRRQIVKKRPGTVAIAAAIQHKYGIPVVPHMVCGGFTKEETEYNLIDLNFLDIHNV
LALRGDGLKTETVFKPEEGGHANANELVDQIANLRKGKYLDSELTNNTPMDFCMGVAGYP
EKHFEAPNMETDLMYLKQKVDAGADYIVTQMFFDNQKYYDFVDRCREIGITVPIIPGIKP
LSLINQITVLPKIFSIDIPEEFSKEVAKCKDNKQAREVGTEWAIHQAKDLIAHGVPCLHV
YTYGIGDNTAQIAKTVF
>M7RK07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Dublin str. UC16|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1T5EA95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Daejeonella lutea|TrEMBL
MKITEHIQNAAGKTLFSFELLPPVKGQSIQGIYDAIDPLMEFNPPFIDVTYHREDYIYKQ
HDNGLLEKVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADSGFIPTPGGHAYATDLLQQVANMNNGIYLHEDHDTAFKTQFCIGVAGY
PEKHFEAPNLKTDFSFLKKKVDMGAEFIVTQMFFDNSKYIDFVKKCRENGINVPIIPGLK
PITSSKQLISLPKIFHIDLPEDLSEAILKCKSEKEVKEVGIQFMIQQCKELMKAGAPVLH
FYTMSNPGPTKRIAEAIF
>A0A2N7PHN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio splendidus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIKIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A365W441|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MWU12-2534b|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLAGYNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLKQYQTAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A6S6RWC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Portiera aleyrodidarum|TrEMBL
MKNKNKKKNKNMNKNELEISFEFFPPNTNDKIKELLNLVKTLYKKINITFCSITFGAGGS
NKKNTLEVIKTIKKNNIECVPHLACISNSKNEIIQLIKMYKNIGIKTILALRGDINKTDN
IKTITNNFINSLDLLTLINKKFYKKFALIVSAYPEMHPNTINFDKEVCFIIKKFLFGANK
AITQYFYDPDSYFYFLEKIIKYGVEQPIIPGIMPIINVKNLIKFSKKCGANIPKWIYKKL
ESCKTDNDIENIGKEIVINLCEILIKGGAQGLHFYTLNKIEPTLNILNELIT
>A0A098L5C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus thermoleovorans B23|TrEMBL
MGLLDKLKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEEAAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTRRSVIVELDPPKQLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIVKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACGGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A1E1KYN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhynchosporium commune|TrEMBL
MEKITDKIAALPPGSSYFSLEFFPPKTTMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELTQRELGLTTCLHLTCTNMSRELVDQALEDAKALGVRNILALRGDPPRSEE
YRDLGEKGTGEGNVDMEEEFEWAIDLVRYIRKQYGDYFCIGVAAYPEGHADESDPAGQSL
EHDLPYLVDKVRAGADFIMTQLFFDVDAYDAFERRLREHESGVFKTIPIIPGMMPIQSYQ
MIKRTTKLSHARMPRNIMERLDRVKGDDEMVKKVGVDIVSEIVTHIQKEPAPGPRGFHFY
TLNLEKAVAFILERTNLIPSSPTDSEFAILDVPSSLESLQINGSSHKRPSRRQSSIGSDP
HNRVIISGSKASNPTRETTADEAGIPAEPVNTRANTLAISEGEGSLGREATWDDFPNGRW
GDARSPAYGEIDGYGVSLHMSVNQAIKLWGFPTSAEDITSLFIRHIEGSIPALPWSEEGL
NEETNTIKSQLLKLNQKGWWTVASQPAVNGVKSSDPIFGWGPKNGFVFQKAFVELFIPAA
GWTSLHAKLTSSTVAPTVSWYASNASGSFLSSSPNGPEEGDGNGGGSTNAVTWGAFPGKE
IITPTIIEEVSFRAWAEEAFGIWGEWGRVYGSRSVSKGVVDGCREGYWLVNVIHHGYIER
EGLWELLLS
>A0A6Q2Y5V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Esox lucius|TrEMBL
MVNQVQTVDDTWRRCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESVLHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPIGTDWEEEEGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAQSYDEDLKHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKENDAAIR
NYGIEHAVGMCRMLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEKSVYEVFTSYIMAEPNQAGHKVMCLPWNDEPLAPETNLLKDELAKVN
RRGVLTINSQPSINGKPSSDSIVGWGPPGGYVFQKAYLEFFTSSENVTALLQVLKKYEPR
VNYHIVNVQGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDVNPLEQCP
>A0A383S2P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas reidholzensis|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMGVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVAAAPHLSCVGDTKADLRALIGEYQAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQAQNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERVQKMGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDTASIQAFG
EDVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A371QJP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodohalobacter sp. SW132|TrEMBL
MKVIEHYEKAKEPLISFEIIPPKRGGAVSNVFESLDKVVEKVKPPFIDVTYHAAEAHVEE
QKDGTLKRVIRRKRPGTIGLCAAILHRYDIDPVPHLICEGFSKEESEDALIELNYLGIHN
VLAIRGDNTGSQTSLNLNGTVNKFAIDLVNQIKNMNQGKYLEDIINAEPTNFCVGVAGYP
EKHFEAPNLDWDIKRLKQKVDAGGDYIVTQMFFDNSAYFTFVEKCRKAGIDVPIVPGLKI
LTTPGHMVRLPRNFHLNIPDALADEVSADEKNARQIGIEWAKQQSLELMEAGVPGLHYYI
MGSPDPALEVIDFLKKK
>A0A239A5B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dokdonia pacifica|TrEMBL
MTKVIDHIAQALEKKETAFSFEILPPLKGQNIDTIFSNIDPLMEFKPPFIDVTYHREEYI
YKERPDGLLEKKVVRKRPGTVGICAAIQNRYSVDAVPHVLCGGFTKEDTENFLIDMDFLG
IENVMALRGDAVKSETYFKPNKNGNMYAQDLVEQIMDLNDGKYLDEDLLNSSKTDFCVGV
AGYPEKHLEAPSLESDIHFLKKKLEAGACYVVTQMFFDNQKYFDFVDKCRAAGITKPIIP
GLKPLSTRKQLNMIPQRFSVDVPDALVMEVVKSKDAAAVRQVGIEWCIQQSKELKEAGVP
VLHYYSMGKSDNIRQIAAGVF
>A0A2E6E5Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia sp|TrEMBL
MGDLDSKTLLDALRGRDFVMTAELSLAPGSHVEEITEQAKALRSHVDAIQVTENQYGALH
MSPLAAASILLAEGVDPIMQISVCNRNRAALIGDLLGARALGIRNVQLVQGKKMPDSYQP
QPTQVKDIDVEELIATTKLINEDSELSGSVDFLIGAVVRARILKQDEKMPMVIGKVDAGA
QLLQTQVCFDLDVLRKYVAKIVSLKLIQRCSVIADIAVFESAESARWLRDNLPHISVPNT
IIRRLERADNPEQEGADICAEYLRELAEIPGLSGANLISIGSPTMKVKAIVSSGVRGE
>A0A369TPW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassococcus profundi|TrEMBL
MTRPEISFEFFPPKNIEATFRLWDTVHVLAPLAPRFVSVTYGAGGTTRDLTRDVVATLHK
HSGLRTAAHLTCVEATREETLQIARDFAAAGVTDIVALRGDPPKGADGFTPHPEGFASSV
ELIEGLKDAGDFTIRVGAYPDVHPEARDQAADIEYLKRKLDAGADEALTQFFFESETFFR
FRDACVKAGIDKPIVPGILPIENWKGARRFAESCGTVIPQWVIDAFETAERDNRQDLLAT
AIATELCSELIDGDVDKLHFYTLNRPELTRDVCFALGVTPDVKLENVA
>A0A1H3XGY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium aggregans|TrEMBL
MSSLLQRTLEAGEFAITAEMAPPKGTDFSHILDIADSMIGRVAAVNVTDFQSAAVKASSL
AMCVELAQKGLEPVLQMTGRDRNRIAIQGEMLSAGHFGIKNLLALTGDHTTTGDNPEAMP
VFELDSVSILQTAEILMSGQDLAGNELAGAPDFYLGACVTPVYDPVEVQLIKMRKKIKAG
AKFFQTQGVFDIDVMRTFKEETKDMDCKILAGIIPLKSAGMAKFMNRCVPGIAVPDALIE
RLTGAEDKVAEGITIAGEFIAQLKEEGLCDGAHIMAIGAEENVVKIMDKAGL
>A0A3E2X1P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi|TrEMBL
MKIKDRLNENRIHISFEVFPPKTDAGYEKVQEATDRIAALNPDFISVTYGAGGGTSKNTA
KIAEHIKEDLGIESLAHLTCASSTKDEVRSVIGSLKELGIENILALRGDIPADMQFPSED
RFHYAYELVEEIRKHGDFCIGAACYPEGHVENEHKADDIKYLKQKVDSGVDFLTTQMFFE
NDIHYNFLYRIREAGITVPVLPGIMPITSAKQMKRSCELSGTVFPRRFQAILDRFGDCPD
AMEQAGIAYATDQIIDLLANGVRNIHIYSMNKPEVAEAIMSNLSEIIKC
>A0A384JMU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryotinia fuckeliana (strain B05.10)|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRALDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDGFEQKLRDHPSGAFKDIPIIPGMMPIQSYQMI
KRTTKLSHAKLPSTIITRLDAVRGDDEMVKKVGVDILSEMVEHLKSTKSQYSGPRGFHFY
TLNLEKAVSFILERTELIPDAETVAALEPEYVPTIPDIADLLSIHSGSHKRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGPKNGFVFQKAFVELFI
PVADWKTLHAKLTSPDLCDTVSFYASNAKGDFISSDEAVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSQTRKIIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLS
>A0A161GP98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus fascians D188|TrEMBL
MTRTPSIVDRLRTEPEARIPFSVEFSPPRDEAAEARLWRAVREFEQLQPAFVSMTYGAGG
STRDRTVRVTGQIAEETTLLPVAHLTAVSHSVAELRSMVGSYADRGITNILVLRGDPPGD
PLGEWEKHPEGVEYAEELVRMVRELGDFHVGVASFPEGHHRADDLEQDTRCLVGKLRAGA
EYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSVRRMLELSGTTLPSH
LDEKFTRAAGSGAEEDKAAVREVGIELATNIGERLIAEGAPGLHFITLNFARATREVLSN
LGLAAARV
>A0A2E6EAN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia sp|TrEMBL
MRTTTTSQMNNHELINDLREAYMEVIPTPNIEEKLRILQPDSYVAVTCSPTKGVDETLDL
SERLVDQGFRVAPHIAAKCVRNETHLSHIMQKLDALKIDSIFVPGGDRAEPLGDFDTAFE
LLKAINNFDHGLKEIGIAAHPEGHPDIADEMLLKELEKKKNLAQYIVTQMCFDADALGKW
LVDISRRGIKLPVWIGLPGAIERTRLFKTSLRIGVGDSLRFLRKKSVVAAELMKSSVYRP
DDLVTDIAQYKNVADTNIAGYHIFCFNQVESTEKWRNETIARLQ
>A0A0K2R778|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Hiyo4|TrEMBL
MFPTRIEIIPSTGIVDKVQALVPLTTTLTMTCLPHHGIERTMRTSVELSTLGYTVIPHLA
ARSIHDQAELTRIMRECDGAGIGEVFVVGGDRKQPAGPYGSALPLLEDIAQYTGGRMRAG
VAGYPEGHPTVAALDLLDALQDKQHLATHVVTQMCFDAPKSSPTRRSCAAKA
>A0A413X2E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi|TrEMBL
MKISDIYNKKKSLSFEIFPPKKDSELENIDETLKVLCELNPDYISVTFGAGGTSNCNRTI
ELAKKIKYEYHIEPVVHLTCLHYDKSEIDKFAKILIDEEIQNILALRGDKNPSIQEKGVF
KHASNLITYLKSKHDFCFLGACYPECHPESDNKINEMKHLKKKVIAGTEILLSQLFFDNE
QFFSFVEECRIADINIPIIPGIMPVINTSQIKRMVTLCGATFPERFQKIILKYENNKKAL
FDAGIAYALSQVIDLLANDIDGIHLYTMNNPLVASKICEGIRNII
>A0A494T8K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. P1Y|TrEMBL
MVDNLRSDSTSSIPFSVEFSPPRDEAAEARLWRAVREFEQMRPAFVSMTYGAGGSTRDRT
VRVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGAYADRGISNILVLRGDPPGDPLGDWE
KHPEGVEYAEELVSLVRELGDFHVGVASFPEGHYRALDLEQDTRVLVDKLRAGAEYSITQ
MFFDVDDYLRLRDRVVAFDPEQGAKPIIPEIMPITSLGTVRRALALSGSALPKALDDRFT
AAAGTGQEEDRAAVREVGIELATNIGERLIAEGAPALHFITLNFSRATREVLTNLGLCPA
RV
>A0A7X0WMJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria innocua|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDKAYLAVYPNASLPEVQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLESTKPILEKEVRPIL
ELVPEEVEDEESGERLLDKVKERLTILVELDPPRTFDTSKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGRANEEGMTIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYVQNKQQVQIASK
>A0A7X8U6N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MSHNKFKASLRDKNKFSVTWELVPGRGAHEKAQDNAILAAEQAARGGRIDALSITDNPGG
KPAMSAAYLGMEILKLGIEPLVHFTCKDKNRNQIESELYALNRAGVRNLLVMTGDYPVSG
FKGRPKPVFDLDSVQAMELISNMNNGLEITEANKSILHQPGDFFAGSVVSPFKATEAELM
SQYQKLGKKISHGAGFIVTQLGFDARKFHEVLQFIRGIDADLPVIGNLYILPYGAARLMN
ANQLPGCVVPDKLLAEIDQERNAADKGVGARLLRAAKMYALMKGMGFDGVDIGGHNIKYE
QVEYIIDQGEELSADWMKLISEFDYPQPHGFYFFAQDEKTGLNTKDPVDRAKLQPELPVG
MNYRMMRLFHQVFFTPDKNLYPLLHKYYAGIKNPRRYKFEHRLKVIGNDCRDCGDCALLD
LAYLCPMSQCPKNQRNGACGGSYDGWCEVFPNEKKCVWVRAYAMLKAYNEESQLENQYLP
PVNWDLYQTSAWYNYYTSRDHSAAKKEDAGLKEKATVNR
>A0A812F7Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. B1ASS3|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDASRDELINIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>L0II97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterium thermosaccharolyticum M0795|TrEMBL
MLNSKNLCQKLNNREFVVTVEMSTPKGADISNSIEEARKLYGIVDALNITDCPMANMRMS
PIALAHLLQNHLNIETIFHLTCRDRNLIGLQAELLGAYALGVRNILALTGDDPKRGDVPQ
ATGVYDVDSIGLIKIAKSLNNGFDYSGNRLESSTSFCIGTTANPNDLSKESIEKLKIKIE
NGASFIQTQPVYDEKILYRFLDAISKFGIPVLVGVLPLKSYKMAVNLNAKVPGIEIPDYI
LERLKNNGKGEGLKIAVEFINKIKNLVSGVHIMPLGRTDIVVDIINNVKNIKTDIKKEVL
>A0A1Z8QEZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED36|TrEMBL
MNDLNQISETVAKRIRQDLQKSYMEIIPVPGIEDKLDSLPSDMYLAVTCSPTKGVDETLE
LSEKLIERGFKVTPHIASKCVSGEKHLEAIIKKLDELGIESIFVPGGDRPEPMGDFNNAL
DLLKALKKLGHNLNKIGMAAHPEGHPDVSDEILMEALEEKKDLADFIVTQMCFDAEILND
WMNQIHNKGIELPVWVGLPGVIERGRLLKTSLRIGVGDSLRFLRKKSQVATELMKSSIYN
PDDLVRDITEQIDINDSKLAGYHIYCFNQIETTEKWRTERISALN
>A0A2V3A0H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. AG844|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWSIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A2E5CFQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MQLSSSNTRIFNHLQNAYMEVIPVPNIEKKLEGLSRSTHLAVTCSPTKGVDETIELSSQL
VDMGFEVTPHIAAKCVTDNSHLSSIISXLKEKNIKSVFVPGGDRPEPAGDFSNAXQLLES
MKDMDVXDMTIGIAAHPEGHPDIKDEVLINELIKKKDLADYVVTQMCFDANILGDWLIKI
KNEGVDLPVWVGLPGVIERGRLLRTSLRXGVGDSLRFLRKKTQVATEIMKSSIYYPDSLV
ESISNYDQIDATNLAGYHIYCFNQIEITEKWRSAKIANMQ
>A0A162DV46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus glucanolyticus|TrEMBL
MKPDLRQAWENQVLVGDGAMGTYLYQKGFPVGISYEELNLTSPEVIGNVHRQYVEAGAQV
IETNTFSANYDKLSKYGLETRVEEINRAGVRIAREAAGNHGYVVGAVGSIRAGKRNNIST
SELKRYFEEQLKVLISEGVDGILLETFYDVDEMQLALAQARMLSDIPVICQFAVEDIART
LDGFTMPDAYRILSQEGADIIGFNCRTGPNGIMRALETLNGVMNLPASVYPNAGIADYVD
GEYRYGASPEYFGKTALEFADRGARIIGGCCGTTPEHISEISLALSGYVPSPLPVVEEAE
VNRIVIHESAQEQFYERSGEPTIVDIVKERHTVIVELDPPRDLDITKFMKGAEALKKAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVVGAAFNP
NVRHLDKAVARLEKKIASGADYVMTQPVYDPELMVRLREATAHLEIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRMRMAGLEGEAGRAMGVKIGKELLDVATELFNGIYLMTPFMFY
EMSVQLMEYVWEKSGRRLTPLFH
>X0ZW63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKVVNLYKGNKPVFSLEVFPPRNGESLEAVLNTIDSLWSFKPAFVSVTGGALGSMRGGTI
AIAAGIKRKYGVEGIPHFTCVNKSKHDIENLLMEMKFNEIENVFALRGDPPMGQKEFIPH
PEGHKYASELVEQIKLLNEGVYILSSVEKDYKVSPTNFGIAVAGYPNGHPECPDKKKDLE
HLKIKVDNGADYIVTQLFFDIDVFLEFVENAKRIGIDIPIVPGVMPMDKYGPIKFVSKQM
GIEIPEKLKDKLEAHKDDKDTIKKILEEHTLLMCKKLVEQGSPGIQFYTMDKPEGTKKIL
QELCKE
>X1F4Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
KGLRDEKKFENGEPIAGREPRLFIGAVTNPFAEPTEHEVIRLGEKVAAGADFMQTQSVYH
IKKFERWMEMVWEGELPKKVKILAGITPLKSVAIARYMKTKLSGVDVPDELIERLRKATT
REQVRKEGIKIAVETINSLKEIEGVAGIHIMAIEWEEVVPEICEASGLYPRTSLEELGRQ
>X1FT50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
YRVHRLAKKVEAGVDFIQTQCIYDMKRFKEFMKQVVDMGLHEKCKILAGVTPLKSVGMAR
YMAANVSGIIIPEEIIDRIKGAGKGNVATEGIKILCEQMQELKETEGIAGIHLMAIEWEH
RVAEIMETAGFLPRPTL
>A0A0F9W766|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MNTALNKPISFEFFPTKTDAGHAKLIAAGHVLAAENPEFFSVTYGAGGSTRDRTRKTVLQ
LDSEVKVATAPHLSCVGDSLEDLRTLLGEYQEAGIKRIVALRGDLPSGMGQASGELRYAN
ELVEFIRKETGNQFTIEVAAYPEAHPQAQHFEADLKNFVRKVQAGADSAITQYFFNADCY
FHFVERARKAGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSDSICA
FGTEVISQMCERLLEGGAPGLHFYTLNQAEPSLDILRNLRTN
>X1LQ56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MASSFKDVLNSSKFVITSEVAPPKGTNLEKILHHIDLLKDKVDAINVTDHQSSVMRFPSI
GGCLAIKEKGGEPILQITCRDRNRLALQAELLFASSRGINNVLCLTGDAVTVGDHKEAKG
VFDLDSLQLLKTIRLMESGQDLGGNNLDGAVEFCAGATVTPEAQPLEPQLIKFEKKVEAG
AEFFQTQGIYDLD
>X0TQ13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKLIDMWNSSPKPTISFELFPARSEKAAESLGKTIDILAALKPDFVSVTFGAGGSTREGS
RQLIEKLKHEKGLEVIAYFAGFGLGPKDIVAVLDKYQAIGIESVLAVRGDTPQEEKFEPH
PDSLPYASDLVAFIRPRYDFCIGVAGYPEGHIDAPSKEKD
>X0UJ21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
ITGDSLQEMMFFHVDSGKLSSVLDHIREGHTVDGKDLPFKAEFIFGSGIESKWGKNVPEL
EMKEMEEMTKIGTGYFLTTPVFDVGLFEKFMKQVNTFGVPVIAEVMILRTAGIAQFLNRH
VKSGLVPDWIIRKLAKAPDRQKASIEIFSEIVSGLKDLCQGIHIITMGAEEKLRHYLDAA
KLKKL
>A0A846ZVI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp|TrEMBL
MTHPLMNELGRTMLVGSGAIGTCLRKADGRSDEPVELLNLREPALVRNLHTAYRDAGSHI
LVTNTFAAQTLALEEAGAGELCDDVNRAGVALAREAGGAQCLVWASIGPLGLGLRLEDYP
DGALEEIYRRQCRALVEADALLLETFVEPREAKAALAAAAATGRPVIFQIGNTGGGGQRW
ERVDRLLAEARLANVAAVGANCRHPNEIVRVAAYLAAYTDWSVTASANAGHPQIERGAVT
YEFSPDDFAAFALELADAGAAVIGGCCGTTPDHIRKLSEALGGRVVAARPRPVAVAAPLP
VVAATAAAAANPVRALVADKRFLISVEIRAERTRTLDEIMQGAAAVAEAGADLFDVPDNP
GATVGRDAMVTAARLQSVLDVPSICHLGVTQSNLMRLHSSLIGGWDLGLRGLLAVTGDAP
SMGHLGNLVQRVTDVRSSVELLRLLRGLREGRIINGEGLADPPDFCAGCAIARPIPPQIK
WLRAKIDAGAEFVFSQPVFTVDDFRRLQDALSELPIRLFPGVMPLTSRRNAAFLAGGRIP
GIAVPPEVAVGFDRYESLQDQRRFGLDQACELAAGIAAEASGLYLIMPFGKSCYEDAARI
VREVKNSG
>A0A348W5I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp|TrEMBL
PVSGYGGRPAPVFDLDPIHTLRLMSDMNKGLTYPGIKGNISHQSSDFFPGAVVSPFKATE
AEQMLQYYKLRKKIDAGAQFIVTQLGYDVRKFHEVFLFMKQNGLNLPLIGNIYILPYGAA
KMMNRNELPGSVVTDKLLAELDRERNESDKGEGARILRAARMYAIMKGMGFSGVHIGGHN
IKYEQVEKIISQGEALISQWADLVRYFDYPIPGGFYYFEQDSKTGLNLDKPTTRQSRPLD
ATVGLSYGFSRFFHNLMFDPGKKFYGVMKGLSGKVAGTKIESIFHKLEHWTKVVIFDCKD
CGDCALIDVAYLCPMSQCPKNQRNGACGGSFEGWCEVYPGKKKCVYVRAYARLKKHEEEA
QLDKGIVAPCNWDLYQTSSWINFYLGRDHTSKKQNSNSSGD
>A0A8B7HS77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcebus murinus|TrEMBL
MMIASTAVNYCGLETILHMTCCCQSQDDITGHLHKAKQLGLKNILALRGDPTGDHWKQEE
GGFNYAVDLVKHIRNEFGDYFDICVAGYPKGHPEAESFEADLKYLKEKVSAGADFIITQL
FFETDTFLHFVKACANMGVTCPILPGIFPIQGYHSLRQLVKLSKLEVPQKIKDIIEPIKD
NDAAIRNYGIELAVNLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPW
AVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLK
SKSPKEELLKMWGEELSSEESVFDVFVRYLSGEPNQNGHKVTCLPWNDEPLAAETSLMKE
ELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVL
KKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFA
LWIEQWGKLYDEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDALELLNRPTQS
EREAEAP
>X1Q0B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
FALDLIGAAALGIKNVLCLTGDHQSFGNHPSSKNVFDVDSIQLIKMFKDMRDEQKFQCGE
KMKHPPEIFIGAAANPFADPFDFRPIRLAKKVNAGVDFIQTQLVYNVEKFKKYMKKIRDM
GLHEKVYILAGVGPIKSVRMAKYMRNNVAGMDVPIEIVERLKKSEDTKDEGMNICVDIIK
EVREIEGVSGVHIMAIAWEEAVPIIVERAGLLQRPKP
>A0A2M9HKF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium felsineum|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGIEDLKPDFISVTYGHGTHSDRTATARIANTIV
NEYRIPAVAHLTALYSDKAKIDEALDMFENAGVNTVLALRGDYIDGEQVVGAFEHASDLV
AYIRERKPNFTVFGACYPEGHYQAESLDKDIEHLKIKVDAGVTHLITQLFYDNDDFYRFR
DKVRAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPEHLDELLTRWEGNAEALHNAGIL
YASEQIADLVAHDVDGVHLYTMNHPATTRRIWRNVKSLFGE
>U2NLB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium intestinale URNW|TrEMBL
MFIKDIFKEKKVVFSFEIFPPKTTTSLDTIYKTIEDLKDLKPDFISVTYGAGGSTIDNKT
TLLSSLIKNKYGIESAAHLTCIGSSKSDIETILEDLKKNNIKNILALRGDIPEDKTSNGE
FSYAYELISHIREHGDFGISAACYPEGHLECRDLDLDIVRLKQKVENGADHLVSQLFFNN
NVFYDFLERCSKKSIDVPIEAGIMPVINKKQIERITALCGAELPEKFIKIMNKYEHNPVA
LRDAGIAYAVEQIVDLLSSGVRGIHLYTMNNPLVARRITESVGSIITSLNKDIIV
>A0A2G2BLD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp|TrEMBL
MTTPAVSFEVFPPKSVDASFRLWDTAQALAPLGPRFFSVTYGAGGSTRDLTHDSAHVLRR
TSGLPVAAHLTCVGASKAETLEVANSFAEIGVTDIVALRGDPENGASVFTPHPDGFADSC
ELIEALAATGKFTLRVGAYPEPHPESPDQAQNVEWLKRKFDAGADEAITQFFFETETFLR
FRDACAAAGITKPITPGIMPVTNWKSARNFATRCGALVPAWLDEAYNAALRDDRHDLLST
ALCSEMCSELVDEGVENLHFYTLNRPELTRSVCRALGVTSQTALSDVA
>N9NWA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter variabilis|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
ERIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>V6SSZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium limnosediminis JC2902|TrEMBL
MKVTQHIENANGKPLFSFEILPPLKGQNIKCIFDNIEPLMEFKPPFIDVTYHREEYEFKE
LPSGLLEKKIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDMDFLGIDN
VVALRGDAVKSEIYFKPEKEGHSYASELVTQINNLNNGVYLDADLQNTNKTSFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGADYIITQMFFDNQKFFEFVDKCRAAGITVPIIPGLK
PISTKKQLNLIPHRFKVDLPDDLIMEVVKAKDNEAVSQIGIEWCIAQSKELAKAGIPVLH
YYSMGKSDNIRQIATEVF
>A0A0T1SUE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Root1304|TrEMBL
MNPTFSFEFFPPKTDRGEQTLWDAIRRVEALSPDFVSVTYGAGGSSRDRTIDVTQRIVTE
TTLRPVAHLTAVGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRGAWTPHPQGFRYAY
ELVELVRSLGDFRIGVAAFPEGHPRSRGPAEDLAHFVAKCRAGADYAITQMFFDPEDYLR
LRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAKDDPAAAYRIG
VEHATRMGLRLLDEGAPGLHYITLNKSTAALHIHRTILSARRVAAHV
>A0A1G3QN17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium RBG_16_49_21|TrEMBL
MKSESDLEKLLNAGKFVVTGELGPPQGNDPEVVKKKAEMLKGNVDAVNITDNQTSVVRMS
SIATAALVVQFGLEPVMQMVCRDRNRIAMQSDIIGANALGIRNMLCLSGDHQTFGNQPYC
KNVYDIDSIQLIYTVKRMRDENKILDVDKEMGGSIRMFIGAAANPFAEPFEFRPYRLKKK
VEAGVDFIQTQCIYDMKIFKEWMKKVRDLGLHERCHILAGITPLKSGGMTRYMAANVSGI
IIPDEIINRMTSAPKGKAAEEGIKICCEQIAEIREIEGVHGIHLMAIEWEHMVGEIVSQA
KLLPRPPVPL
>A0A2Z6GFG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferriphaselus amnicola|TrEMBL
MNKTPISFEFFPPQTPEGLGKLADTCKQLALYKPEYFSVTFGAGGSTRDRTLATVEQILH
QGYGAAPHLSCVGSTRENIREILHTYKALGVKRIVALRGDLPSGMATTGEFQYANELVSF
IRAETGEHFHLEVAAYPEVHPQARSARDDLLNFKRKMHAGANAAITQYFYNADAYFHFVE
QARKQGITQPIVPGIMPIMKYSQLARFSEMCGAEIPRWMRKTLEGYGDDTDSVQAFGRDA
VTQLCEQLLTAGVPGLHFYTLNQAAASTEILKRLGYRA
>A0A0D8CZM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassomonas actiniarum|TrEMBL
MGYSHAREVESLNRSLSEISKDIQVSFEFFPPNSPEMETTLWNSIERLAPLKPSFVSVTY
GAGSGTRDRTHDVIKRIQKDTALIAAPHLTCIDAGKEELVQIAKDYWQSGVRHIVALRGD
LPNSSEKPSMYASDLVELLKSVADFDISVAAYPEGHPEAPNPQFDLLNLKRKVESGANRA
ISQFFFDIESYLRFRDRCVTVGIDVEIIPGILPVTNYKMLERFAGLTNVHVPSWMPKMYE
GLDDDETTRRLVGANIAMEQVKVLNKEGVKNFHFYTLNRAELTYAICHTLGIRP
>A0A3M7IZF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMSYDAEIFIEWAKKVRAAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAQLFVKYMSGKVETLPWSEQPISPESNVL
TNDLVNLNSRGLLTINSQPAVDGMKSSHPVYGWGPNNGYVYQKAYLEVLIPPSLIAELIR
RMDANPDITYYAVNNSGELKTNAPQDGGPNAVTWGVFPGKEIVQPTIVETISFLAWRDEF
YHLGSEWAKCYDEGSQSKNLIKEITESWYLVNIVDNDFRNMRGIFPLFDGLKVDGVEPTA
AAVNGAAVNGEANGGDVEKKEGARKPEVNGVPDGNNAVNHADGPAVNGQVKN
>G8PUV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudovibrio sp. (strain FO-BEG1)|TrEMBL
MEQQLWSSIKRLEPLSPSFVSVTYGAGGSTRERTHSTVSRIVNETALKPAAHLTCVDATK
EEVNEVIQAYWDAGVRHIVALRGDPAAGLGEKYHPHEGGYQSTADLVASIKTIGDFEVSV
SAYPEKHPESPSWDAELDVLKAKVDAGATRAITQFFFDNDHYFRYVDRVRAAGINIPIIP
GIVPVTSFKGISGFAKKTGASVPGWLAHRFDGLDDDPRTRELVAAAVAAEQVMSLADDGV
EDFHFYTMNKADLVYAICHMLGLRAKQDVKASVAA
>A0A1S9RKA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium brasilianum|TrEMBL
MHIREKLASKEAAGEPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGHLS
DLTCEMVGVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEATENGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSSF
VITQMFYDVDNFIEWVKKCRAKGINVPIIPGIMPIQQYASFIRRSNWTKTRVPPEWMEAL
EPVKNDDSAVREIGKRLIADMCRKVMASGINHLHFYTMNLAQATKLVLEELGLAPSDEAP
IQRALPWRPSLALGRRGEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGEVDA
YGVRLKGTNEQNIKLWGEPKSIKDLSEIFVRFLEGKLDRLPWSDSPISAEANDIKDLLVD
LNRRGFLTINSQPAVNGVKSSHPIYGWGPKNGFVYQKAYLELLVPPSLIDELVARIDKNN
DLTYHAIRKNGELRTNTHDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYRLGEDWS
KCHDSSSPSRKLIQQVMDDWYLVNIVDNDFHRNNAVFELFTDLEVKDLNVELPGKPETNG
STEQNGAATKN
>W0VCJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium agaricidamnosum NBRC 102515 = DSM 9628|TrEMBL
MDTANFSIEFFPPKTPEGAEKLRVTRQQLSALHPKYFSVTFGAGGTTQQGTLDTVREIQA
AGEEAAPHLSCIGGSRESIRSILQQFKADGIQRVVALRGDLPSGYGASGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQARSPQDDLQNFARKVQAGANAAITQYFYNADAYFQFVE
QTRKLGLDVPVVAGIMPITNYTQLVRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTQLCERLLAGGAPGLHFYSMNQAGPTSALWQRLAG
>A0A5J5F3D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerosporella brunnea|TrEMBL
MEKIVDKIAALPPGERFHSLEFFPPKTDMARSDPPAGFQNLSARLERMAQALRPLFVTVT
WGAGGSTSAKSLQLAEICQRDLNLTTCLHLTCTNMSKKVLDDALESAKRIGIRNILALRG
DPPRDEEYFNTKEEVEGEEGQREFVWAIDLVRYIREKYGDYFCIGVAAYPEGYAEGTCPE
HQDPKRDLPYLIDKVKAGADFIMTQLFYDAERYLDFEALLRNDPSGVFKDITILPGLMPI
QSYTILRRTTKLSNATLPQSIQERLEGIKGDDAKVKKVGIEILSEIIDRLCTGLPNPDRR
PQGFHFYTLNLEKVVSFVLERCGLIPAHDEDAIVEEETTDTIIINGQRRDRRTSSLADPN
NHVIVDKVEGRRESCTLLEAAKQAGFLKTAEHPEVTLAISEGEGALGREATWDDFPNGRF
GDARSPAFGDIDGYGPSLHMSHSQAQNLWGFPVTVEDINNLFVRHITGDLSAIPWSEQGL
NDESKVIQQQLVSLNRKGWWTVASQPAVNSCRSDDPTFGWGPPGGFVFQKAFVEFFCPDE
DLVRIQAKLKEMGDGAVSFYAANNKGEYRSNMPPSDESLNAVTWGVFTGKEIITPTIIEE
VNFMAWKEEAFSIWHEWSRVYPPRSPTAAFLANVASTYWLVNIIHHDFPEADSLWSLLEG
L
>H6NEK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus mucilaginosus 3016|TrEMBL
MLKEKIQGRKPGIITYGITPPKQNHPPEKIAEIAKKQIDRIADIGIDGLIIYDIQDEADR
IDQERPFPYLSTVDPTTYSKEYLGPLTVPHIIYRSVGKYSESELSGWISSDPGQDRFSVY
VGASSSKQEVRLSLPQAYELSRHLNDTLHFGGVVIPERHLTRKDEHLRMISKMNSGCQFF
VSQATYDVEASKNVLSEYYYTCQEQGLEMVPILFNLTPCGSLKTLEFMKWLGISVPKWLE
NDLMHSNDILDKSVRLTLKIMEELMDFGLEKGIPIGCSVESVSTRKVEIDASVQLLKDVK
QSMESRLLQPQSL
>A0A2T5QIW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIDKVLHFSGK
ARDIQDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKEHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTQHAYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYVEQNRHLTLEALEELWNSLWQVTTGKEFSPEIAHFSR
QPTPKQIIKYRQLHVMHEAMFGSKIAKGVGRFIFRASFWENALVAKVLIKTEVLSKHSLV
GCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKQT
EILKEKLIPTVPIETRGTSSWKNWYLATEA
>A0A7W6MMR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantimonas endophytica|TrEMBL
MSHALPQTRDVIPASIEVAPRQAVRSTELPGLFPPRTRTYLTDVGVDSVKDFVAATRRIA
DLGYVPVPHIPARRIRSRDELQTRIRAYAEEAGVTDVLVIGGGLDRPAGPYTSSMEILES
GLLDRHGISEIGVAGHPEGSPEFSLATAEAALRLKRDFCERTGARMRIVTQFGFDADAYV
DWAMAVRESGIGLPIHIGVAGPASITTLIRYAALCGVGSSVTFLKKRTGALAALAAHHSP
ESVVGPIEQHWRQTPESPIRQIHVFPFGGLAQSATWLRERGSWPGSVAERALG
>A0A7Y4R981|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MRIRDALNQPRPALSFEFFPPKDEIGFWDLFKTIGALKPLAPTYVSVTYGAGGSTRRHTV
NLVERIKNDLAIETMAHLTCVDATRAEIAAVLDELKGSGIENVLALRGDPPQGSQRFVKT
EGGFAFANELVAFIRERYDFCIAAACYPECHPECKDVRRDMDNLKRKVDAGVDILITQLF
FDNADFYAFRDRAERAGITVPIIAGIMPVLSVKQIKRFTTMCGATIPAPLLARIESVEDD
AEAVRHLGVYHATEQCNDLLDNAVAGIHFYTLNRSTATRAIFQQIKTRLPVTR
>A0A7Y3K2K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHILDIFARDTTTFSFEFFPPKSDQAAAQLFDHIAQLEPLAPSFVSVTYGAGGSTRQRTH
ELVLRLKQQTTLDPVPHLTCVSHKRADIQDILTRYAAAQVGNILALGGDVSRDVAGYDRA
HDDFKHAADLVRFIREFNRASLHPEPRGFGVGVAGFPEGHPATPNRLQEMDYLKAKVDAG
ADYICTQLFFDNHDFYDFRERCELAGIRVPIIAGIMPITSVSGMKRMAELALGAHYPARL
LRAINRAGDDADAVRRVGIHWATEQCRDLLDNQIRGLHFYTLNNSYATLEIYRNLGVKNS
AALR
>A0A7V1MBL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHIRDVFNRQKTTFSFEFFPPKSAEGADRLFKSISELERLEPAFVSVTYGAGGATRDLTN
DLVVRINKETSLDAMPHLTCVCHSRDEIQRLLERYAAQGISNILALRGDPPADNPDHRHE
DDDYRFAAQLVGAIRRFNELGTHPNGKGFGIGVAGFPAGHPATPNRLDEMDHLRAKVDAG
ADFIITQLFFDNASFLDFRDRCRFCGIDIPIIAGIMPLTSLSGMRRMAQLALGTHFPARL
LRALDRTDGTPESIRRVGVHWATEQCVDLLDHGVDGIHFYTLNQSTATREIYATLGVQSS
SQLSS
>A0A8C3W3G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catagonus wagneri|TrEMBL
MDRPKARVLPAGRCRPSLGVRASEAGISRSSVPPAISRHSAMVNEPRGNGGPSPRWEGSS
SGSESSKDSSRCSTPGLEPERHERLREKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
YLRKAKRLGLKNILALRGDPAGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFFKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSRLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATTEVLKRLGLWIEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPLVGW
GPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGKLYEEESPSRAIIQYIHDNYFLVN
LVDNEFPLDSCLWQVVEDTFELLSRPPQNKEEAEAQ
>A0A0K9H281|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. FJAT-27231|TrEMBL
MTLLERLQNEVLIADGAMGTLLYSYGIDFCYEELNIEKPEIIEKIHREYIKAGADVIQTN
TYSANALKLTRYGMEDRVEELNKAAVRIAKKAAAPDQRFVLGTIGGMRGIRKSSVSLADI
KASFQQQAEAILLEEPDGFLLETYYDFEELTTVLQLLRQMTDLPIISQVSMHEPGILQNG
LSLNHAFKQLEALGANVVGVNCRLGPYHTIQAFEEVTLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGQAAVHLRNEGVRLIGGCCGTTPKHIEAAKKALAGLAPITEKKVVAKKPII
IKEPAPLVVPPLHEQVKKERTIIVELDTPKHLDTATYIKGAKALQQTGMAAITMADNSLA
SPRVSNLAMGSLLKMQHQIRPLVHITCRDRNLIGLQSHLMGLHALGLHDVLAITGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGISFSGKPLKQKANFSVAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPIFTKEKIVEVYEATKHLPTPIFLGIMPLTSSRNAEFLHHEVPGI
KLSEETLARMKAHENDKEAAALEGLAIAKELIDTAAKLFNGIYIITPFMRYEMSIELIHY
IEELDGKTNERGIAHVQTIFN
>A0A7J4VZX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neorhizobium sp. P12A|TrEMBL
MALKTESSRRDIRISFEFFPPKSDEMEAQLWETVPELAAWQPEFVTVTYGAGGSTKEPTL
AAVRRMISEKRLPTAAHLTCVDASQDEVKAVVEEYRAAGVRRIVALRGDPAAGIGSAYTP
HPQGFSDTADLVRMLVDYGDFDISVSAYPEKHPESPDMAADIATLKRKADAGATRALTQF
FFENDAFERYLERAHAAGVTMPIVPGIMPIQNLTQLKRFARRCGSTVPAFLDDRFEGLDE
KPEERAEVAADVAAEQIEDLIRRGIREFHLYTMNRAPLIGAVLERLGFRRDTDIRAAGAA
A
>A0A6N2EFP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHFRDIFVQQNRTCSFEFFPPKTDPAAEELFGTLTQFQTLRPSFVSVTYGAGGSTRERTH
GLVLRMKRETALDPVPHLTCVCHDETEIGKVLERYAEAGISNIMALRGDEPKDYDGKAGS
FPFATDLVRFIRKFGERGGHADKRGFGIGVAGYPEGHPSTPNRLLEMDYLKAKVDAGADA
IVTQLFFDNHDFYDFRERCELAGIRVPIIAGIMPITSIKGMKRMAELAAGARYPASLIRA
MNRTDGSDEAAKRVGVHWATEQCRDLLDHQVDGLHFYTLNRSTATRDIYASLGVKDSLAL
AV
>A0A7W1T8L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria rustica|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARIAAPSL
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIVANVSMHEPGLL
QSGQTLASALQELADLGADVVGANCRLGPYHMSKALESVPLLENAYLAAYPNASLPQMDE
GKVIYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRRGLKSIKPVTSKVVHPIL
ELAELDAAEDAGVRLTDKVKEQYTVLVELDPPRTFDTAKFFEGAQELDAAGVDAITISDN
SLATPRISNMALAAILKQEYDIRPLIHLTTRDHNLIGMHSHIMGFHKLGIQDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALVEAGITVPVFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREADKSGTGREEGMAIAKEILDAICEHFNGVYIITPFLHYDLSIE
LTKYVQSKEQVIEISSQN
>A0A4Y3JDD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIDKVLHFSGK
ARDIQDFERFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPCKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQVKSFLTKNNYSQ
QILACVMPLTLGRANFMVKHKVAGIVITSHMLKVLADEKQAGHTDRVYLRCALQILIYKH
LGFTGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVTTGKEFTPEITRFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALVAKVLLKTEVLSKHSLV
GCESCGHCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQT
EILKEKLIPTVPLETRGTSSWKNWYLAT
>A0A7L5A9Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulicella sp. WH15|TrEMBL
MKTGKVAESLFGGGSERKVVLCDGAMGSMLYGRGVFINRCYDELNLSQPDVVRGVHLEYL
QAGAEVIETNTYGANSIRLKRFGLEARVAEINLAGVRLARECVDQMREKQGSEAFVAGAM
GSLGDLTVSAEEAFAAFSEQVRALAQGGPGVGADLLIVETLPGMLEAEQAIRAAKAEAPA
LPLIVMVTVSESGDCLDGTSPEEAARRMTEWGADAIGCNCSDGPATVLSVIERMRPMTTL
PLAAMPNAGQPRAIDGRSLYLTSPEYMASFARRFVQAGATFVGGCCGTTPQHTRAMRGAL
RALEAQATGVQAVESGAAARVVASKVEPPPLAERSRVGAKIATGAFVTMVEIVPPKGIDT
THELEGAEELHRLGVDAINVPDSPRASARMSAQSLCVQIQQRVGIETILHYTCRDRNLLS
IQSDLIGASSIGLKNVLCLTGDPPKMGTYPDATAVFDVDAIGLVKIVEGLNHGLDIGGNA
IGASTGFTISVAANPGVPDIDNEVRRFAAKVEAGAEFGITQPVFDMRLLEQFLKRIEGFR
IPIVAGIWPLTSVKNAEFMKNDLKVSMPDEIMRRMAAAGSPEAARATGIAIAQEMLTAAR
TMVQGVQVSAPFGKYKAAAQVLGVV
>A0A7Y5SVB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHIRDLFIQHSTTFSFEFFPPKSPSAAEDLFSSISDLTSLKPSFVSVTYGAGGSTRELTH
DLVVRLRTQTPLDPIPHLTCVGHDDAEIGQILERYAQAGISTIMALRGDLPREGCNGGDP
WRSFRYASELVRYIHKFNERRIHPDKRGFGVCVAGYPEGHSETPNRMREIEFLKAKVDAG
ADAIVTQLFFNNHDFYDFRSRCELAGIRVPIIAGIMPVTSIAGMKRMAELALGARYPATM
LRALARAGDDDEGVRRVGIHWATEQCRDLLDHGVAGIHFYTLNRSTATREVYATLGVKDS
HQLRR
>A0A3V2ZXF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella newport|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1E2YRM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MSHVSPCFQQNQFFMLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFEHFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHSGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQVKSFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLTEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYVEQYRHLELKVLEELWNSLWQVT
SGKEFSPEITHFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGLGRFIFKASFWENAVVAK
VLIKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKDKLIPTVPLETRGTSSWKNWYLATEA
>A0A5J6LNF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. LPB0220|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFAHQPNFEVN
>A0A3D1EUA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MFSERGPTASFEFFPPKDGEAWDALFAGISAFEQLQPSFVSVTYGAGGSTRARTHDLVVR
LRSETSLLPMPHLTGRGHTKAEIESILERFAESGVDNILALRGDPPKDGDLGPGDFPHAI
DLVRFIQSFNESGGHPNGGFAIGIAGYPEGHHETPNLLTEMDHFRAKVDAGADFAISQLF
FDNRRFLDWRDRCSMAGIQIPLVAGLMPITSAGGMRRMAELAAGTLIPARLLRGVLDREA
DPEMVEAFGVLWATEQSRDLLDHGVAGLHYYTLNR
>A0A5A7ZZH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. P1-11|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTDEMEKILWNSIERLAPLQPSFVSVTYGAGGSTR
ERTHNTVARMVRETGLKPAAHLTCVDASREEIDAVVQSYWDAGVRHIVALRGDPAEGVGH
AYRPHPEGYASTAELVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQA
ITQFFFENEIYLRYLEKVRAAGITIPIIPGILPVQNFKQAANFARRTGASVPYWLAARFE
GLENDVETRRLVAGAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AAKAAA
>A0A5S4ET32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter phosphatis|TrEMBL
MLEIQREGHQAAPHLSCIGSTPDSIRSILKQYQAHGIRHLVALRGDLPSGMARPGTFRYA
NELVEFIRAETGDWFHIEVAAYPEYHPQAKSPMEDLLAFKRKLDAGANSAITQYFYNFDA
YAHFIDECQALGIDVPIVPGIMPISSYSSLARFSDNCGAEIPRWVRKKLESYGDDTLSIH
AFGLDVVSSLCAKLLASGAPGLHFYTLNQVELTTTLWQRLGLSRRY
>R5CE01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:598|TrEMBL
MKVVDLINSNQHTAFSFEVLPPLKGTGIEKLYATIDLLREFDPKYINITTHRSEYVYQEL
GNGLYQRKRLRRRPGTVAVAAAIQNKYGLTTVPHLLCSGFTREDTEYVLLDLQFLGITDL
LVLRGDKAKHEARFVPEEGGYSHAIELEEQINRFNQGIFEDGSPMTVTRTPFSYGVACYP
EKHDEAPNLESDLMWLKRKVDAGAQYAVTQLFYDNNRYFDFVERARKAGITVPIIPGIKP
LKRAAQLSIIPKTFKVDIPQELAEEVERCKDDEQVKQVGIEWCVRQCRELMAHGVPSLHF
YSVAAEDSIREVAKQIF
>A0A1H1U9Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium timonense|TrEMBL
MRGNNPSSRLSTPTPRVWATHPLVSASAPLDGPDDPPPAPKPATRTALSFELIPPRGSAD
AERLGALIQGLAAYRPDYVSVTSSRRSGWLAGTAELISLLASRTNLRTIAHLACTAGTRE
ELAEWIRTLLDAGVRGFLALRGDLPEGETRLPAGYLQHATDLLNLIQDVEDEEAFHLAAG
KLALSVACYPAGHAESRNRDEDLDVLLAKQRLGADFAITQLFFDAQDYLSFAETSRMAGV
RIPLIPGIMPMTSLKRVERMGVLSGVTVPDRVIDRLSAAATPEEEYEVGMELSADMTRTI
LDAGAGGLHIYTHNNIAVTRDLLDRVGIPRPQ
>A0A368KBC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium salinisoli|TrEMBL
MSRIAASIEVAPKQAIESQELPGLFPAGSRVYITDIGTDSVDTLTAAAKRVHDLGYKPVP
HFACRRLTTKEALETRIRRAAEEAGVTDVLVIGGGLERPAGEFNSTMQVLETGFFDRYGI
TEIGVAGHPEGSPDFSESVAIEALRLKRNFGERTGARLRIVTQFGFDADHFIAWAEGLRE
AGIDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNAFALTALATTHSPEGVVGPIE
RHMLENPASNIKQVHVFPFGGIKKASEWLVERGTWNLDPAAPVAAAQ
>A0A2T5B8U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycoplana dimorpha|TrEMBL
MAHFDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGV
GPMASAKTARWIRSNVPGIHIPDSVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEIVHESGVLKGRKPWRREPNPVDQLVAERIERTREGVEQNQQQMAEIAA
QTPPLIRAGAPAGMSLPTLKIER
>A0A034VUF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bactrocera dorsalis|TrEMBL
MALKTPPNCERTKAFYATLKSSAISLHRSERIQLFENLFVNQIAIACGYGRTTKVPLTQN
QKKISILNQNLRRSDIRIQKTMHNPDYVPATNCCNATTSICGGHVPLPTAPEFHPIYVRF
SSKQQAPEQRKLAELFKQKVAAKEFFYGIELTARSYGKQPSLLDYNGFDVLLPLFTSLVW
LGRDYANVEDVNAIEAISLGRQLQPHVVVMPHFTCYRADSRRLDDFLTLNFTNVLALRGD
DVVPQQQFQHAKDMVEYIRSKRGDTISIGVAGYPDGHPESKSLDEDMQYLKEKVDAGADF
IVTQICFSPESIISFVQKCRKMGITVPIIVGVIVPDNMRILQFIMNIVKAVIPEEQLSKY
KELEGDRKAFKAYAVENAVRTVQMLLDSNLDVYGFQFFTMNRLKSVQQVIQQILNMNQTQ
SI
>A0A7X7ZG11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brooklawnia sp|TrEMBL
MGLTVADRPTIASVPTDQTIGELLATATAPTFSFEFFPPKDEAGQQLLTKTIGELEPLCP
DWVSVTYGANGSSRQRTLDATMAILQTTDFRVMGHLTCTGQSVDELKAVIDAYGDAGVRN
ILAIRGDMPGGPSVPWERYPGGLANATELVELVRSRGDFCVGVAAFPDGHATSTLEQDAE
ILLGKQQAGASFAVTQLFFEVGHYFELVGRARSAGCTLPIVPGIMPVTSVKQLGRFAEMS
GADIPARVAERLLAAPDDPAQVRITGSQIAAELCERLLAGRAPGLHFFTQNRSVATREIL
AMLRGDHR
>A0A8E1ZDY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MNIKNLFRDKKVVFSFEIFPPKTTSSIQTIYNTLDDLKGLNPDYISVTYGAGGSVKNNKT
IELTSLIKNKYGIEAVSHLTCISSTKSDIEYYLREFEKNNIENILALRGDIPIGSKITGE
LNHANELIKHISDNGQFNIAAACYPEGHIEHKGLYREIESMKRKEEAGASYFISQLFFDN
NLYYNFQDEVRAANINLPIEAGIMPVTNKRQIERILSLSGASLPDKFKRIMERYEHNPEA
LRDAGIAYAVEQIVDLISTGVDGIHLYVMNNPYVAKRISQSIENILLTVNQNQFV
>A0A8J6TA87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfacyla euxinica|TrEMBL
MSTKTPSRLEKILDSGQLAVTSECGPPRGSDPEAITKKAEIIKDHVDAINITDNQTSVTR
LSSLAACIHLKLMGIESTLQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQMFGDSP
QGQNVFDLDSMQLIQTVRLMRDEGKFLGGDDIKRPPKMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNLDKFELWMKEARDRGLHEKVYILAGVTPFKSAGMAKYMKNRVPG
MDVPDEVVKRMAGVPKENQPEEGIDICVETIQRLKECEGVRGFHVMAIEWEEKVPEIVER
GGLYPRPEDL
>A0A257VK21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriia bacterium 12-62-4|TrEMBL
MSSATLPKTRAKEFREALAHGVLVADGAMGTMLYEKGVFINRCYDELNLSAPHLVKEVHE
AYVKAGAQILEANTFGANRGRLATFSLGEKLVAINQAGVRLAREAAGEVAFVAGSIGPSG
MRNASPEELRDIFTEQATVLVEAGVDLLVLETFFAIDELREAVAAVRAVAGPELAIIAQV
TINDDGAMLDGTSTEDFTALLDQWPVDVIGLNCSVGPKATLETVERIMRQTSKPVSAMPN
AGHPADVEGRKIYLCSPEYMSQYARRFLWAGVKIVGGCCGTTPEHIKLVRSEARSLQPGH
QTLPVTVDETKPPVVKMPLVPVAEKSKLGAKLAAKQFVTFVEILPPRGVDPSREVAGAIL
CRDAGIDVINVPDGPRASARLSAAITCKIFQEQAGIEAVLHFCCRDRNILGMQSDLLGAH
ALGVRNLICITGDPPRMGAHQHATAVFDVDAIGLADIVTNLNSGLDIGGNAMGSQTALLL
GVGANPGALNIDEEVRRFERKVAAGAEYVVTQPVFDIKLLENFLKRTEHCRIPVVCGIWP
LTSYRNAQFMVDELRVPVPEPFMQRMQRAADAEAARQEGIAIAQEMTREVQWMVEGIQLS
APFGRYQMAVDVATVIEKR
>A0A0E3LTT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina mazei S-6|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRFSASLEDASQLKGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDYPTCGDHPGSKP
VYDVDSVQLIELVRKLDTGVDFAGNKLDGGTSFCAGAVSGIDPEKTMQLIKLQKKVKCGA
DFIQTQAVYDIGMFEEFMDAVNYLEVPVIAGLIPLKSLGMAEFMNKNISGIHVPEEIMLR
MKDASSPMEEGLLIASETIKELTKLSRGIHVMPIGSHRNTARLLSLAGISQK
>A0A3C1MH09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
AGAQALKTNTFGAYASLVGGPEKQAEIIWKGLSLAEEALRDYRELDSAPGNRPVYIFADL
GPAPGDTPEQKAEQYIQAAELFLQAGAKHFLFETQTVTDGLVEATRYIKKQRPDAFILVS
FGVLPDGYSTAGQFYRQMILEVLESGYVDLAGLNCVSSPGHMAKLLGKLPEELLLRIAAM
PNAGYPVVRGFRTFFDGSAKYFQGTMKRFLDMGIHVLGGCCGTTPDYIRGLAELAVDQVV
VPHDYTSPYHGKGENPREGEAYHGTINRLLTKLRRGKRVIAVELDSPRNAELDRFMEGAK
RLQAAGVDTLTIADCPIAQARMDSTLLACKVKRELDLDVIPHMTCRDRNVNATKALLLGG
HAEGIRNVLVITGDPIPTAERDEVKTVYQFNSRKLMSFVSSLNQEEFHPDPYGIFGALNV
NARNFSVELDRAKEKMENGCMGFLTQPVLTEQAIQNLKQAKAELEGAYILAGLIPVISER
NGRFMDQEINGISVPEEMIESFHGLNREKGEALGRKYVNDIYHEIKEYTDGVYLMTPFQR
IGLMEGIVRDLLQE
>A0A7U9MPQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MCLRGIHKLDKPKLTLAQKLRRNEVKMIISNLFEKKKPVISFEIFPPKKEAELQNIDATL
QTLATLHPDFISVTFGAGGSSADNRTVKLAQKIKKDYGIEPLVHLTCISNSKEEIKEILG
QMESAGLKNVLALRGDVNPNVPAKDDFRYASELVSFIKEQGDFHVSGACYPEVHLEAADE
VSDLRNLRKKVDAGAEHLVSQLFFDNNKFYDFLSKVRIAGIDAPVEAGIMPVTNKAQIKR
MVTMCGAALPEKFERILERYGENKEALFDAGMVYAVNQIVELISSGVDGIHIFTMNNPVV
AGRICEEIKNLI
>A0A8F8G8P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp. Y33R10-2|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPQFCSVTYGAGGSTQAGTFTMVKDIQSE
GVNAASHFSCIGATQDSVRAELTELKAMGVKRIVALRGDLPSGYGLGGEFHYASDLVAFV
RQEFGDWFYIEIAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VKALGLDIPVVPGIMPITSSTQLMRFSDACGTEIPRWIRLRLQAYGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A0L9T7R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaseolus angularis|TrEMBL
MKIIEKIRDAAADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANRMQNIVCVETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVKHIRAKYGDYFGITVAGYPEAHPDVIGSDGLATAEGYQKDLEYL
KSKIDAGADVIVTQLFYDTDTFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPADIMSALEPIKDNEEAVKSYGVHLGTEMCKKILSHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPTNVFRVKEDVRPIFWYVTFAIVMSCSIT
>A0A352CSF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKITDLFERGEFAVSAEVGPPKGIHIEEMIEDAKKYLGGVDAINVTDCQSSVMRVGSLAV
CKELKDAGMNPIFQMACRDRNRIALESDLLSAAMFGIDNVLALTGDHTKMGDHPQAKPVF
DLDSVSLLHTMCVLESGKDLGGNDLVGEPPKFAKGAVVSPCSDSVDAQLVKMEKKIEAGA
EFFQTQAVFDSEKFIRFMERAKQFGKPVMLGIIIPKSAGMCKFMNNNVAGISVPDSILEE
LKADKEKTKAGITGVEIAARIIRECKPYCQGVHIMSLGWESKIPSLLEQSGLAR
>A0A416GI16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. OF04-15BH|TrEMBL
MNVIDLINSTKSTAFSFEVLPPLKGTGIDALFRTIEQLKEFDPKYVNITTHRSEYVYKDA
GNGLMQRARLRRRPGTIAVAAAIQNKYNLHVVPHILCSGFSKEDIEYMLLDLQFLGISDL
LVLRGDKAKEDASFKPTPGGYSHATELIGQINRFNEGFFVDDTPIKVPGVPFSYGVACYP
EKHEEAPNLETDLQMLKLKADLGARYAVTQLYYDNEKYFSFVERARAIGINIPIIPGIKP
LAKLSQLTMVPKTFHCDLPLALSSEIQKCKSDEEVKQVGIEWAVQQCKELMAHGVPSIHF
YTVSAVDSIREIARQIY
>A0A6B4S1A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MNIKNLFKDKKVVFSFEIFPPKTTSSIQTIYDTLDDLKGLNPDYMSVTYGAGGSVKNNNT
IELSSLIKNKYGIEPVSHLTCINLTKKDVEYYLREFEKNNIENILALRGDVPIGSKITGE
LNHANELIKYISDNGNFNIAAACYPEGHIEHKGLYREIESMKRKEEAGVSYFISQLFFDN
NLYYNFQDEVRAANINLPIEAGIMPVTNKKQIERILSLSGASLPDKFKRIMERYEHNPEA
LRDAGIAYAVEQIVDLISTGVDGIHLYIMNNPYVAKRISQSIESILLTVNQI
>A0A2G2FCD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fluviicola sp|TrEMBL
MKVIDHINESNETLFSFEILPPLKGKSIQSIFNGIDPLMEFKPKFINVTYHREEYIYKER
DKGLLEKVAIRKRPGTVGICAAIMNKYHVDAVPHLICGGFSKDETENALIDLQFLGIDNV
LALRGDPIKTESSFTPNPNGHKYAVNLIEQIVQMNKGTYTLDDIQLEPTNFCIGAAGYPE
KHFEAMNMATDLQYLKQKVDKGADYIVTQLFYDNKKFFEFVDKCRAAGITVPIIPGLKPV
TKLRHISFLPKFFNIDFPDELSSELLKCKTDEEVRNLGIEWGIAQTKELKEANVPCIHYY
TMSNSSEVKSIASEVF
>A0A2I9DUG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus aerius|TrEMBL
MTTTPRTRVSVELVPRSRSGLRAELEVVANHLPGIDTVNVPDLTRFSTRSWVGCSFARPR
YRAIPHVRAVDLNPVEPLPMAETLEAAGIDEVLVITGDAPADMSARVYDVDAVRAIRRFR
RELPHVRVYAGLDPYRQSFARERDYLERKLDAGACGFFTQPFFDLRLMDAFADLIPEGVE
VWWGATTVTNDATLNYWRARNHAVFPRSFQPTLEWNREFAARTLAFARERGHHAYFMPVR
ADVRAYLEGIV
>A0A3C0LUG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKLSEKMKEKQLLSFELFPPKTEKGMANLPGTIEHLMEFKPEYISCTYGAGGGNVGANRE
VCQMIKKAGSIPVTHFTVIKNTKEGIREQLDQYLEEGVDHMLALRGDFPMGETSTMGDFD
YATDLVKFVRDQYGDKFEVAVAGSPEGHISCRSLEADIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGVTMPVDVGVMPILDQAATINMALSRNGCVMDRELSRLISRHWLFPN
PFAAKDAEGKPFDLFYDKKIAEFKEEGIEYTIRQIDTYRALGVEGIHLYALNKWKDVSEI
INRSGLRTLV
>A0A239R3Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKISEVYKNKKRSLSFEIYPPKKDTELENIDDTLEILAELKPDFISVTFGAGGSSNNNRT
IELAKKIKFQYGVEPVVHLTCLHYDKQEIDEFARVLEAEGIENVLALRGDRNDRVPEKND
FKHSSDLISYLKPNHDFCFLGACYPEKHPESDTRVRDIKDLKTKVDAGAEVLVSQLFFDN
NSFFNFKESCSMADIDVPLIPGVMPVINAAQIKRIVHLCGASFPERFQRIIDRYENNRDA
LFDAGMSYALSQIIDLLVSDIQGIHLYTMNNPAVARRICEGIKNII
>A0A1C5DZ02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MnatMP-M17|TrEMBL
MAAQNPERPEHPRPGPRVRPADGGRSYSFEFFPPKTEAGERTLWNAIRRIEALAPSFVSV
TYGAGGSSRDRTIEVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGIRDVLALR
GDPPGDPRGEWVRHPEGFAQASELVSLIRELGDFTVGVAAFPERHPRSADWESDIRHFVA
KCRAGADYAITQMFFHVEDYLRLRDRIEAAGCTTPIIPEIMPATDHRQIRRFAELSDARF
PDELAARLEAARDQPGEGHRIGVEYATAMAERLLAEGAPGLHYITLNRSTATMEIHQNLG
VGAGARNVPVPVPAPAA
>A0A3B9INQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tistrella mobilis|TrEMBL
MMTVTTDGRVLTPRALWDAPAPVPGLKISLEFFPPRGAQAEARLWENVARLAAYAPDFVS
VTYGAGGSTRDKTRDTVLRMRRDYGLAAAAHLTCVDASRTDVMAVAEGYIADGIDHVVAL
RGDPPQGAGPYVPHPDGFPFAVDLVRALADLGRFEISVAAYPEVHPQAQSAGADLDNLKA
KLDAGATRAITQYFFDPAVFLRFRDRAAAAGITRPILPGLMPVLGFQQIKRFSAACGAGI
PDWMERLYDGADADEATHQAVSAMLLAEQARVLAAEGCADLHFYTLNKAELTISACHLLG
IRPRAEVAAARAAG
>Q0KF23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLENFVRKVKAGANSAITQYFYNADAYFRFVD
DVRATGLEVPIVPGIMPITNYTQLMRFSESCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A418W9G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleomonas cavernae|TrEMBL
MILAPLGPLNVSFEFFPPKTPEMEDALWRTVRRLEPLQPSFVSVTYGAGGSTRERTHATV
KRLVDETSLNPAAHLTCVAAAKGEVDEVAREYWDAGVRHIVALRGDPQVPGSPYEPHPGG
YTRAADLVAGLKRVADFEISVAAYPEIHPEAPSPGVDLDNLKRKIDAGATRAITQFFFYN
DVYFRFLDRVLAAGITVPVVPGIIPVSNFKQIVRFAAACGAAIPGTMARHFEGLDEDPET
RKLVATTIAAEQVRGLAAAGIKDFHFYTLNRADLCFALCHLLGLRAAPTAVAA
>E0XYM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Chloroflexi bacterium HF0770_09E03|TrEMBL
MKISDTINDFKTQGKTFYSFEFFPPKSDYALDNLYSRIDRMASLQPAYIDITWGAGGSTA
KRTLEMSKTIQKYFGLEVMMHLTCTNMPVSSINKVLINAKENGLSNILALRGDPPDGAVE
WENNEKGFNYGIDLVRYIRKAFGDDFFLGVGGYPDSHQEQTDFDLDISYLKEKVDAGSNI
VVTQLFYDVDKFLVFRDKCSAIGIHVPIIPGIMPIHNYSRFIKFTQFCDVTVPDSVSKTL
ESLKHDDSSVIHYGIEQGTAMCEKLIAEGVPGLHFYTLNLEHSVSRILESLGLASVQGSA
RELPWRQSTVGDRKTTEDVRPIYWSNRPVSYLTRTETWDDFPNGRWGDITSPTFGELNQY
HSIRAGSKSEKGKTRRKKLWGEPISVNDITKVFVSFCEDKINSLPWCDSPLEIESKKISK
ELVKLNKSGFYTINSQPQVNGAPSEDPDVGWGAPGGRVYQKSYLEFFTSKDKLDTLLKIL
NSSNNISYQAINRNGDLISNVPENSVNAVTWGVFPGHEIVQPTIVDTRSFLIWKDEAFSL
WINDWAHIYDTESESYKLLNEIYDTYYLVNIVDNNFVDGDILNRILKSH
>A0A4R2S1J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Baia soyae|TrEMBL
MNRMGIIEYLKNHLVVGDGAMATYLYQEGAPVGTCYELYNLTHPKMIADVHQAYEQAGSK
LITTNTYGANRERLERYGYGHKVTRINREAIKIARESIQSDTYIAGSIGSIVAGRVTQYD
SDEYHDLYEEQATALLHAGVDIILLETFMDLQELLVAINAIRPLTDTPIVAQLSLLEVSR
TRDGHSLTDAFAQLQKHGVSGVGLNCRMGPLEIIRALEKTIIPPDLLISAFPNAGRLGES
DGELRYKSAPSYFGETAQLLINQGVSMIGGCCGTTPEHIREIAQIAQNQTPVTRINPPVV
PEACEVLSQPPKRTESTVLEKVARERTIICEFDPPKDLDVQSFLLGSQELYKSGVDAVTL
ADNSLASARMSNLALGALLKSQLGIEPLIHVSCRDRNLLGQQSHLMGLHALGIDQILVIT
GDPTRIGDLPGASSVYDVTSFELISMIKQMNQGLAFTGRPLKQQAQFIVGSAFNPHVRQI
ESAVTRLEKKIQAGADYAMTQPIYDKQGIIKLYEATRHLEIPIFVGIMPLTGYRNALFLH
NEVPGIKIADDVIRRFESIKDPTVARQVGVEIAKDLLDTAMTYFPGIYLITPFSYWPMTV
ELTRYIREKDTRAAQDSA
>A0A7X6N984|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio aestuarianus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASREELIQIADDYWNNGIQSIVALRGD
IPVGGGKPEMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFD
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A518ILR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia fumaroli|TrEMBL
MRISELYRSGTFDLSVEIFPPKNESGDAELFRTLEELIRYQPAFVSCTYGAGGSTSKRTI
ELCETIQNQLHTTATAHFTCVASTRDQLVDWLQSASDAGINNIMALRGDPPKGQETFVPA
DGGLKYANELVALIREHFPQMGIGVAGYPEVHPESPDAETDLANLKRKVDAGANAVYTQL
FFNNTHFHNFRERCVQAGITCPIIPGIMPITEFRRIQRISSMCNSEFPVELTEKLEAVQE
DLEAQFEIGVDFAIRQCQELIDDGVPGIHFYALNRSPACKRIFEALGFHEA
>A0A3N2K6I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Isolate-042|TrEMBL
MKVTDIIAARQTPGFSFEVLPPLKGRGINQLFKNIDILCEFDPLYINITTHRSEIVFKDT
SDGLYRRVSERSRPGTVAVAAAIQQKYGIPAVPHMICSGFSKIETEYALIDLNFLGITNL
LLLRGDKAKHESRFTPNADGHAHASELQQQVNDFNRGYFIDGTKMDIITGETFSYGVAGY
PEKHEESPNPDIDLQYLKLKVDNGADYIVTQMFFDNEKYFRFVERCRNAGINVPIIPGLK
PITTMSQLNLLPKVFHVDMPSDLANELMKCTSDAQAKEIGVEWCTMQARELIAHNVPSIH
FYSLNATRSVERVARTVY
>A0A0C2HWW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geoalkalibacter ferrihydriticus DSM 17813|TrEMBL
MSRFAEKLAGGEFVVTAEIAPPKGVSLDQELALAASLPAEVTAVNVTDNQGANMRMAPLA
VAALLRQRGIEPILQMTCRDRNRMALQSDLLAASALGIENLLLLSGDHPRFGDHPQARPV
FDLDSVQLLRAAEALMAGHDLAGRPLQTSPVFFPGAAVTPEAEPFELMFQKVQKKAASGA
RFFQTQAVFREESLRRFMAQARPLGVPVVLGVILLKNVRMARYLNEHIPGVRVPEDIMTR
LSEAADPLEQGVIIAREMVALARSECQGVHLMTLGCEDRIPQILC
>A0A2G9XIF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium CG23_combo_of_CG06-09_8_20_14_all_48_27|TrEMBL
MTISFKETLASGKFIVTSEVGPPKGTNLEKMIHHIALLKESVAAINLTDHQSSIMRYPSL
GAALLVKEQGGEPILQMTCRDRNRLALQADLLFAYSRGIKNVLCLTGDSLVVGDHKEARG
VFDLDSSQLLAAIRTLEKGKDMGGNDLDGTVSFCAGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVYDLDKFRDFMSYARQFPVKILAGIILLTSAPMARYMNKNVPGVRVPQELID
EMAAAPKGSTLSKGIEIAGRMIREIKDDRICDGVHVMAIGKEEVVPEILKEAGL
>A0A2W5AL76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagerythrobacter marensis|TrEMBL
MTSPTLEQMRAAQTALEAPLFAGLPGDVEVSFEFFPPKNESMAETLWQSVQTLAPLGPRF
VSVTYGAGGTTRQRTHDAVIRIERDTDIPVAAHLTCVEASREEVDAIARDYWANGVRHIV
ALRGDPPQAGTRYTPHADGYANAAELVAGLKAIAPFDISVAAYPETHPDSPDLAADLDNL
KGKLDAGANRAITQFFFEPDCFFRFRDAATGAGIDAEIVPGIMPVLSFASVERMSGLCGT
AIPAWMADLFTGLDERPAARQLVSATIAAELCRKLYAGGVRQFHFYTLNRAELSYAICHM
LGLRPKEMP
>A0A0N0JFG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. AAP116|TrEMBL
MPERPIAKTPDARISFEFFPPKSPDMEDQLWQAVKALQPYQPDFVSVTYGAGGTTREPTL
ATVKRLIAETPLATASHLTCVGATRDEVRAVVEEFQAAGVRHFVALRGDPQGGVGSRYAP
HPGGFVNAADLVSGLRDLGDFEISVSAYPERHPESENDDVDLDMLKQKVDAGATRALTQF
FFDNDIFERYLERVRAAGITIPIVPGIMPIQNLTQLKRFASMCGASTPSFLDERFEGTEG
DAQARAAVAADIAAEQIADLARRGIEEFHIYTMNRAPLTIATLDRLGITAKAAKVSSAAA
>S3ACL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. oral taxon 186 str. F0373|TrEMBL
MALKWGIEAGADRPHDPDPRGNRAKMAHEPRVGAPAAAVTASPRVPFSFEIYPPRTPEQL
PALYETIRVLAAAGPRFISVTFGAGGSTTDRSLTVLTHILRETTVPPVAHVTCVGSSYAE
ATTVIRDFLDAGITRFLALRGDPPVGIGEDDIVFGDLESAAQLVQLIGRVQAERSPYRER
EIPGLPGAVQVTDGDRVQIAVAAFPNGHPRSRHRYEDIDALLAKQAAGATSALTQLFFHA
DEYLDFVERARAAGVVIPIVPGIMPITSPGRLRRVLELTGDARPDALAAALESAPDAAAQ
RAVGLAHAADLARSVVAGGADGIHLYAFNNHDTVLGVLRAAELISEASP
>A0A095WQB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. YS-1r|TrEMBL
MTAHRESFSVSFEFFPPKSDEMEIQLWETVEQLSGWDPDFVSVTYGAGGSTKEPTLAAVT
RMIGEEKLPTAAHLTCVDASRDEIRSVIEDYRVAGVRRIVALRGDPTSGIGTAYAPHPEG
FAETADLVRALVEYGDFDVSVSAYPEKHPESADLAADIDTLKRKADAGAARALSQFFFDN
DIFERYLEKVRAAGIGIPVVPGIMPIQNLTQLKRFARRCGSSVPAFLDARFEGLDEKPEE
REKVAADIAAEQMEDLGRRGIRDFHIYTMNRAPLVSAVLQRLGRRQISSPRIAAA
>A0A6G1JQT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pleomassaria siparia CBS 279.74|TrEMBL
MMEKVTDKINALPEGASYFSLEFFPPKTSPGFANLQGRLERMSQALRPLFVTVTWGAGGS
TATKSLELAEICQRQLGLTTCLHLTCTNMSRSLVDEALEQAKVLGIRNILALRGDAPRSE
EYREHGQSPEEDSNKDFTWAIDLVKYIRKQYGDYFCIGVAAYPEGHSDESHPEHQDPSFD
IPYLVEKTKAGADFIMTQLFFDVTAFDKFEETLRNHESGVFKTIPIIPGLMPIQSYNILR
RTTNLSHASLPAHILNRLDAVKGDDELVKQVGVKIISEMIEHIKKRPSAGPRGFHFYSLN
LEKAVSHIVEECSLIQQTVTADEGAIDFDGPDILLSPPDGLARRRRLSSMNSSPHNRVII
SQHSKSSHASFEASESEAGIPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGDARS
PAFGEIDGYGPTLHVSTPQALKLWGHPVSKDDISHIFRKHIEGELEAIPWSEQGLSPETS
TIAEELLALNAKGWWTVASQPAVNGVPSNDPIFGWGPKNGFVFQKPFVELFVPSADWKAL
QLRLDAHEQITYFAGNASGDFEASSDDGVNPVTWGTFSGKEIITPTIIEAVSFKSWQEEA
YSIWREWQRIYPSKSATARLLGEIREDVWLVNVIWGDFVEGKGIWDFLMG
>A0A507AXU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thyridium curvatum|TrEMBL
MDKITDKVAALPPDASYFSLEFFPPKTAMGFSNLRYRLDRMSRALRPLFVNVTWGAGGST
AQKSLELAEICQRELGVTTCMHLTCTNMSKDLIDNALADAKALGIRNILALRGDPPRPTE
YRAEGEEVQEGAQEFTWAIDLVRYIRKNHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVEKTKAGADFIMTQLFFDIEAYKKFETTLREHPSGVFKDILIIPGLMPIQNYQMIKRT
TKLSHARIPDALMARLDEVKKDDEKVKSVGVDIVSELVEQVKEFTGKKGPKGIHFYTLNL
EKAVSFIVERTGLIPPYTPETESAVVDDATSLAVPAIQVNGTGSSGAGQASSRTRKSSMN
SDPRNRVIVSGPASHPDYEVTALEASVPAEPVNSRANTLAISEGEGVLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVAQALKHWGTPTTKDDISQLFVRHLKGELSAIPWSEE
EFNAETGTITGQLIKLNSKGWWTVASQPAVNGLKSEDPIFGWGPQHGFVFQKAFVEFFIM
DSEWEVLRERLSRPEMKNHICFYAANATGDFQSSDFSGGLDKEVKEASTNAVTWGVFPAK
EIITPTIIEEVSFRAWAEEAFGIWGEWAKVYPKGSESDRLLEGIKSGYWLVNLIHHDFVE
SDALWELLSQ
>A0A7M7H5P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nasonia vitripennis|TrEMBL
MEFIRGICYRRRGRRRDACRFFRDTQICEPLFYALTWHEGWATGEERFPSLKSAEVFPRN
TLLHCTAKGLKKTDAEMILTRALELGIANIFALQGDSGSDDGDFDHASDLVKFIRERYGQ
QFSICVAGYPEMHPHSPSKELDIFYLKAKVDAGADFILTQFFFESQLFIKFVNDCREVGI
SVPIIPGIYPFTDVKLLGKMIEICHTNIPDWIQEELRHIEDDDEAVRKFGIDLSVKLIKE
IRESAHFCGYHVYTLNRSFSAIEVHRQLNTQHEIDQLVASNS
>A0A521G179|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electronema sp. GS|TrEMBL
MKPDFLEYVHDHVVLGDGALGSYLFEQGVERGRNLDLLNIQSPEIIFAAHEEYIRAGSQL
IETNTFGANRFKLREAGAGERAREISRLGAEIAAKAAGQQVYVAGSVGPTGLAFPLDEEE
TAVDAIQDSFREQVLGLAEGGADLLILETFSNLEEILLAIEAARSVAPQLPVVAQMVFPA
KGLTVLGEDALICGQRMRAAGAALVGTNCGRGVDATVQAIVRMSPLAAEGTPLSAFPNAG
LPEMLDGRMIYPAQPSYMAVRAKEMIRNGVHLIGGCCGTQPAHIQEFRSVLRIKPVRVQV
SGIAVKAEEPATAPVAAKNGGFLDSLQPGRLPIIVELDPPAHLDVEPVLRGAAELVKAGT
DAISLGENPLAVLRAGNLSLAALIRQRTGIQTILHQTGRDVNALGLQSRMMDAHLLGIEA
VLAVSGDSAAGTDQPGVSGVFDLRSYGLISMLEGLNRGQSMAGQPLRQQCNFSIGCAFSY
RPSDPETQLRRLEKKAELGARFAMTQPLFSVAAVEQMLEQVRHLDILVFPGIFPLISARN
AEFLHNEVPGISVPQELRNRLAQFSQVADQRKAALEYTAALVAQIAPFIDGLYLISPLNK
WDIALEFVVQARQAGWKGSGRADRIHQHF
>A0A7H2PXK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIEDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKAFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDH
VYLRCALQILICKYLGYAGIHLSACHKPEEQMLLESYVEQYRHLELKALEELWNSLWQVT
SGKEFSPEISSFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGLGRFIFKASFWENTLVAK
VLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKEKLIPTVPIETRGTSSWKNWYLVTEA
>A0A7S1UIH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeomonas parva|TrEMBL
MEALADTLADPARPSFLFGVTPPREGTSAGKCREICSKFVARQRALATDGFIVYDIQDES
SRNNEKRPFPFRSLLDPSWYAGLFQAESGKQCLVYKCTPNTESEEHFMSWLEEANRLHRH
RAFNLVGAASSSQEVKGPSVEESAALLRGYGKLDASKRCRFGCVTIAERHAQKHREHDNM
LRKIGWGAEWFVSQGIYDPDAMVELINDYAALCRSRGIVPKKVLLTFVPCGRKKTLQFIK
WLGMKIPQHAEERIFRAAEDPTTSPVEMSCQLNRENLIKILEGTSGCGVPLGLNVESVSG
YRDEIDATHQLFRDLQCILLDHRGSPWMVRWYDVPRTIGEQHRARGLSMGSDGDMVAASE
SQRQMLQEFQQMLASAQATVDSARGAQSFQAGQAALCAFGGAAVASSVLLAGLFVGLKMG
GK
>A0A166ATC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudovibrio axinellae|TrEMBL
MSEHSIDRRFRLNGASDISVSFEFFPPKSEKMEQRLWSSIKRLEPLAPSFVSVTYGAGGS
TRERTHATVSRIVNETCLKPAAHLTCVDATKEEVNEVIQAYWDAGVRHIVALRGDPAAGL
GEKYAPHEGGYRTTADLVASIRSIGDFEVSVSAYPEKHPESPSWDAELDVLKAKVDAGAT
RAITQFFFDNDHYFRYVDRVRSAGITIPIVPGIVPVTSFKGISGFAKKTGASVPGWLAHR
FNGLGDDPRTSELVAAAVAAEQVMSLADDGVEDFHFYTMNKADLVYAICHMLGLRENRKV
RTSVAA
>A0A2N1ZBM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium HGW-Gammaproteobacteria-11|TrEMBL
MTNNTNKAPVSFEFFPTKTEAGHEKLIATGKILAAENPEFFSVTYGAGGSTRDGTLKTVL
QLDQEVQVPTAPHLSCVGDSKDDLRSLLNLYKDAGIKRIVALRGDLPSGMGQASGELRYA
NELVEFIRNETGDHFTIEVAAYPEAHPQARHFEADLENFIRKAKSGADSAITQYFFTADC
YFYFVDRVRKAGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLESYGDDSESIG
AFGTQVITELCQRLIEGGAPSLHFYTLNQAEPSLAVWRNL
>A0A0A0JVJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Knoellia aerolata DSM 18566|TrEMBL
MGPRSIPALLAGERPSVSFEFFPPKDDASEAALWDAIRRLERVRPDFVSVTYGAGGSTQD
RTVRVTERIARETTLTPLAHLTCVGASVEDIRRVVGQYAASGVRNILALRGDPPGNPGGE
WVAHPDGLDHATDLVSLIRTLGDFTIGVAAFPDVHPASPDLDHDVEIMVRKADAGASFAI
TQMVFDADSYLRLRDRVAERRDLPITPGLMPVTNLRQIKRMSELMGMPLPRAVVDRLEAV
GDDVDAVRAVGVEIATELARRMLAEGAPGLHFITMNRSTATLEVYDNLGLSAGAH
>A0A0Q0WRD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium aquidurense|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
VMALRGDAMKDEQYFMPKAGGNDYAIDLVKQISLLNQGKYLHEVMDADNRANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFNFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDSCKNNAEIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASHLF
>A0A1X6YLV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius albus|TrEMBL
MTTPKISFEFFPPRSLEASFRLWDTAMALAPFSPDFVSVTYGAGGTTRKLTQETVSALHN
TTDLNVAAHLTCVDASREETLEIAKQFAREGVTEITALRGDPPAGTGPFQARKDGFANSC
ELVDALARTGNFKIRVGAYPEVHPEAANQAADIDWLKRKIDAGASEIITQFFFEADVFFR
FRDACDKAGITVPILPGILPIENWKNARAFSQRCGASIPDWLDQAFDKALRDDREQLLAT
SVATELCTDLIEGGVEQLHFYTLNRPELTRNICLALGLKTQQALRHVA
>A0A5M6IRB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovastum atsumiense|TrEMBL
MRISVELVPRSEAALLADAATVRDALPQASALNIPDLLRFPLRSWEACALTHGVMPASIP
HIRAIDIPPGEDLPMAEAILAAGLTEILVIKGDPPHDMSRRTWPNSSEDIIRRCKRRHPG
LRVYAAFDPYRQGFRDELDAVARKRDAGADGFFTQPLFDLRLLEICAEMLRGQCVFWGIA
PVLGERSRAYWETTNRVIFPADFAATLEWNRDFARRALATIDELGGNAYLMPVRVNLDAY
LRGLLPG
>A0A7L4WES3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus paracarnosus|TrEMBL
MKITDIYKTKNKKNKSVISLEIFPPKTDAGVETIYHTVAGLTNKPDFISVTYGAMGSFNQ
GNKTLRIAEKIKKDYNIETMHHLTSINNNPEQIAAILSDIKAKNVNNILALSGDMPVGAA
CSDFPDAYHFAYELINDIKKNGDFDIAAAIYPEGHVNSALEVENIEHVKRKYDAGANLFV
SQLFFDNEKFLRLNDYIKNSGIEAPIAAGIMPVLQKSQVERMIFFGASLPTRLIKIINKY
KDSPEDLQKAGMEYACKQIDDLLARGVDGVHIYTMNKPFVANTMMTKYL
>A0A246PXU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. K2I17|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKYLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8B2Z2F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ligilactobacillus ruminis|TrEMBL
MSQTTFSFEIFPPNKESAAEKLTETLDELVGLSPDFISVTCTNKNDDLARLTVKLAGYVK
NRLDVPSIAHLPAAYLDKQQVSEILNELETLGVTNLLALRGDRIEGRKPKDDFRHASDLI
AYVHENFPEFHISAACYPEIHPESDSRVDDIKHLKYKTDQGVDSLITQMFFDNESFYGFK
ECCELADINAPIVAGIMPIVRRNQALRILKTSSATLPKKFTAILNKYQDDPESLRAAGLA
YAIDQIVDLVTQGVAGIHLYTMNDAKTAEAIWQATRSLFENGRKVHQV
>A0A8H3B7E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKVTEKIQQAEKDGRIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSELVKTCQGAIGIETCMHLTCTNMHQEKVDIALREAKANGCRNILALRGDPPSGQEE
WTSVEGGFQHGIDLVRYIRREYGNYFDIAVAGFPQTIQLPEAEAKQEMQWLKEKCDAGAN
FIFTQMFYDADVFIRWVKAAREAGITIPIVPGINPIQTWNGFIRATSLSGTEIPQDLMDT
LEPHKNNDEKVRELGIKIVANLCRRILDAGIGIKGLHFYTMNLEKGTKMLLEELNLVPRV
ETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQTPEEGRKIWGTPTTIDDVKDLFAKFCSKEIKALPWSDQPPSTEMLVIGQQLT
RMNELGYLTINSQPAVNGVRSDDKAFGWGPKNGYVYQKAYLEFFVHPDQLQTLMKRIERD
TNVTYYAINKQGDLKTNSTSDGPTAVTWGVFPGKEVVQPTIVEAVSFMAWKDEAFELGCQ
WAKIYEPGSPSRKLIEDMMDEYFLVNLVHNDFHDREAIFRPFFADAGLKTNGCTEAPATN
GIKQVNGLTNGHAMTVHA
>A0A7X4XLM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. V27_P1S3P104|TrEMBL
MGYTHASHIDALNQSISEVSDINVSFEFFPPSTPKMEETLWNSVHRLKNLNPKFVSVTYG
ANSGERDRTHSIIKAIKEQTGLIAAPHLTCIDASRDELITIADDYWHNGIQSIVALRGDI
PLGGGKPEMYAADLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPQWMAKQFDG
LDDDPVTRQLVGASQAIDMIRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPR
>A0A8H8PAH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKLSEKLQIYIDAPYFTFEFFPPRTEQGYSNLLTRITGLASLKPIAASVTWGAGGSTRDR
SLDLAAFCQAENGLDTILHLTCTNMEKGTIDEALTTAMEKGVSTTGTSRRSSQRRGVLDS
YRPRFQHAEDLVTYIKQHPKFGNHFCIGVAGYPDGHSEGGSEEEQLTHLKRKVEAGAEFI
ITQLFYDVEKFKSWLRKVRNTGIRTSNTWNDAPTNVRNFYPDDRFMQSYALEATQHAATS
LAEHTRTGTLRTAAEAINSGWDDFPNGRFGDSKSPAFGAVDPWDGGGLGVPPHVAISQWG
RPTTEQDLADLFLAYLNHKAPTTPFSPTPLSDESITILPHLISLTSKGLWTVASQPAVDG
ILSSDPVVGWGPKDGRVFQKSEVAKAIEDSGDGWVTFFAGNNDDGFLSNIPDSGSNAVTW
GVFPGQEIAQPTIIDRDSFLAWKASIYTWTMREIAIEYMEQDDAFMIWHDFGLCYSPDSP
TRKLLENVTKTRWLVSIVHHDYKDPNALWDFLAKHLN
>A0A8H3DWR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKLTEKLASYASNAPYFTFEFFPPRTDQASATLHSSQPHSELTVFEQGYSNLLTRITGLA
SLKPIATSVTWGAGGSTRDRSLDLAGFCQADSGLDTILHLTCTNMEKGAIDEALTTAMEK
GVSTVLALRGDPPRGEEYWIPADPRFRHAEDLVTYIKQHPKFGSHFCIGVAGYPDGHSEG
GSEEDQLAHLKNKVDAGAEFIITQLFYDVEKFKSWLRKVRNTGITVPVIPGVMPLQTYAT
FTRMTDLCKATVPQHIQANLDAIKHDDQLVKEYGVSLAVSMVRSILVDGDIKGVHFCTLN
LEKSVRKILDELGWTHESLHHNQIITDASQSPRILPAPADVPHPVTFTISPSEATQHAAS
SLTEHTRTGTLRTAAEAIDSGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPPHVAVSQW
GRPTTEQELSDLFLAYLNNKAPTTPFSPEPLSNESSTILPHLVSLTKRGLWTVASQPAVD
GALSSDPVVGWGPRDGRVFQKSFVEFFATEADLEKVAKAIEDSGDGWVTFFAGNNDDGFL
TNIPDSGSNAVTWGVFPGKEIAQPTIIDRDSFLAWKDDAFMIWHDFGLCYPPDSPTRNLL
ENIIKTRWLVSIVHHDYKNPNALWDFLAEHLE
>A0A0W0I343|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas viridiflava ICMP 13104|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLELE
NEVKVPAAPHLSCVGDSKEELRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VNFIREETGSHFHIEVAAYPEMHPQARNFEDDLQHFVNKANAGADSAITQYFFNADSYFN
FVERVEKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLQLPR
>A0A1L3L4U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium americanum CCGM7|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMEIQLFQTVADLSVFAPAFQTVTYGAGGSTKAR
SLTTVKRMIGEMGLENTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGSA
YEPFPGGYESSAALVKALRARGDFEISVSAYPEKHPESADVAADIDMLKRKVDSGATRAL
TQFFFNNDDFERYIERVRRAGVQIPVVPGILPINNLTQVIRFAGLCGSKVPEVIISRLAH
LDDQPEERFKEASHIAAEQVVDLARRGFRDFHLYTMNRSPLIAAVCDLVGYQRRPARPTA
APSYPAVATA
>A0A4S2H4Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinicauda algicola|TrEMBL
MTQPPREAVARPKVSFEFFPPKSEEMEERLWDSISRLEPMDPAFVSVTYGAGGSTRDRTH
RTVRRIVKETGLKPAAHLTCVCATKDEINEVIRDYWDAGVRHIVALRGDPPEGIGETYQP
YPGGYINAADLAGGIKTIGDFEISVGCYPEKHPESPTWDYDLDLLKQKIDNGATRAITQF
FFDPEVFFRYRERAVKAGIDIPIVPGIMLQPNFKGLTRMASMCGASIPSWMDELYEGLDE
DVKTREMVTANIAANLCTELARGGVDQFHFYTLNRAELALSTCRLLGVKPREMEPA
>A0A2D5UWG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MATAIEQIQAAAANWSIEVTPTGATKIESFRDCLNEGTTVNVTFLPGTDPADTIAVCERL
HNDGMKPVPHLAARSLRNADQLDELLTAYTSRCGVEEVLCIGGGVDXPVGXFTATMEVLK
TGLIQKHGIRHIGVAGHPEGSPDISDDEIAEALGAKNELARAEGLDLYIETQFCFEADIV
LDWERRVRAAGNALPIRIGIPGPATIKTLFRFAQISGIGPSMRFVAKQAKNVAKLMTVQS
PHLLIAGLAEGMAADGDCLIRHFHFYPFGGFARTATYAGAIADGKIEMLPKGGFNVTEG
>A0A4U0P3Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium olei|TrEMBL
MKIVDHIKNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYLYKQ
HDNGLLERVAYRKRPGTVAICAAIMSKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDSDFIPTPGGHAYATDLLQQVADMNRGQYLHEDIELSEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVDMGAEFIVTQMFYNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSDAVSECKTNADVRQVGGEWLVEQCKELIKFGAPVLH
FYTMSNPGPTKKIVEKLF
>A0A0H2VFI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A349HJN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp|TrEMBL
MQVAQSINEAGQFFSFEFFPPKDKSTWPVFMERAARLAALNPLFASVTYGAGGTSHDNSL
EICSMLKKDMGIDIVAHLTCVGASEQSIDEFVNRLGEAGVSDILALGGDGVRDANVNAES
RFFHASDLVEYVDGKFSEVGLAVAGYPGGHPESPSISMDIEIHNSKLSKGADFTMTQLFF
DNRLYFDYVDRLAELGSTAPVIPGVLPIQSLSSLRRIMSLCGAAIPGDLYCGVEKAFEKG
GDEAVMEFGFDFARKQIADLLDKGAPGVHIYSLNRAAMCERLITDLKSDGYFN
>A0A377NJG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ewingella americana|TrEMBL
MSFFHANQREALNQNLSELQGQFNVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERERTHSIIKGIKDRTGLEAAPHLTCVDASREELTQIAQDYWDSGIRHIVALRGD
LPPGGGIPELYATDLVQLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPHWMTRQFE
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGLATPL
SAAV
>A0A1C3V7S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium shewense|TrEMBL
MTDLTIPARADGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPPA
GIGTAYSSHPDGYQTSAALVAGIKKRHADIEVSVSAYPEKHPEARDFDDDIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A0Q7ZG76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root151|TrEMBL
MDIAARIKSGQGDFVIFAVTPPRRSTPTDRLPEIARATVERLEHLDLDGLVLYDIDDESS
RNPEERPFPFSPTVDPAEYRAEHLEQWGTPVIVYRAVGKYQREDLRSWIAEQDPRRTLSV
MVGAASSGSSPSVSLADAQAMSVALNPDLLLGGVAIPERHSRRENEHLRLIAKQEAGCRF
FVTQVVYDLNAAKNLVSDYRYECESRGLVPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLRHAANPLLASLAQATATAVELIDYCRRLGVPFGLNVESVSIRREEIEASVELAGQL
AGHLRK
>A0A7C7QLS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MSLIQKLGKDFVITTELGPVKGALFKDSLDKAREYLALDAINIHDCPMGNLRINSIAMAH
VIQSELGVESIPHFTCRDRSLLGTQADLLGAHALGIRYVLVTTGDPPKHGPYPSKPVYDY
NVFELINLIKKMNSGLDYNDKEFGGNTDFNISCTALPTARDIDQELKKMERKIKAGADFF
QTQVVYDAERTITFINSAKVLGKPILIGIMPLKSLKMARYMKEKVEGIDVPDEIISRMEK
EGVSGIQIVCDVIRDIYEYVDGIHIMALGDVKGTNQIIEYVKGLSSGTSVARS
>A0A7Y3GHK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKVKTPSKLEKVLAAGHLAVTSECGPPRGSDPEPIIKKAEMIKDHVDAINITDNQTSVTR
MCSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAASFDINNILCLSGDHQSFGDCA
QGQNVHDVDSMQLIQTVRHMRDESKFLGGDDIARPPQMFVGAAANPFADPFEIRVPRLAK
KVAAGAEFIQTQCIYNLDKFEEWMKLVVDRGLDEKISILAGMTHMKSAGMAKYMKNRVPG
MDVPDEIVKRLADTPKEKQAEEGINICVEAIQRIKEMKGIKGFHVMAIEWEEKVPEIVER
AGLHPRPDLN
>A0A1J9UPG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus paramycoides|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADIIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQDGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPEFIEQGIRLLGGCCGTTPEHIAGMKRAIANIAPVIAKETIPRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKETAIEEGIRISQQLIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEVKEVKEGIN
>A0A7C0YBV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MSEYKSGSNLERVLKAGHFAFTGECGPPQGANVEKLREKAQHLKSMVDAVNVTDNQTAVV
RMSSWAASLILLQEGLEPNFQMVCRDRNRLAMQSDILGVYAHGIRNMLCLSGDHQKFGNH
PQAKNVYDIDSMQLIHAVKTMRDEGKFLNGEQIDEPPKLFIGAACNPFADPFEFRVYRLA
KKIEAGADFIQTQCIYNMDKFRQFMKRVVDMGLHEKCYILAGVTPMKSVGMARYMAKQVP
GMDVPDSLIKRLQGAGKGKVAEEGIKFAVEQIEEF
>S3N807|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter rudis CIP 110305|TrEMBL
MSQLSNIFAENQFCVLVEYLTSLKELFPVVTEFAGFPALMTLADRVHSDDDVAPLVAAQQ
FPAEVDKVLHYAGKGRDIAEFKQFLQQAQTAGQHNLLLLTGDKLKHHESGEHGARTRYLE
SVNAVMAAKQHGGFCIGVAFNPFKYTEAEIDAQYLKLHKKVKAGADFIITQLGYDIAALK
QLQRFLKRHSYAQKLLACVMPLTLARANFMLKQQVAGIVITPRMVEVLEQEKSLGLTERV
YERCALQILIYQHLGFAGVHLSACHKPEEQQLLQSYIERYRHLDLADCEQMWHDLWEDQS
DEVFRPNVNTYSKKVSLGQIVKYQQLHLMHDAVFNSKLGLGLGHMIFNQGFWNKKPAAKA
LLKTELLSKHSVVGCDNCGQCRLADTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKVRLAKAVEQTDVLKDQLIDAVPIEVRGSSSWRNWYLKDDH
>A0A5M3WM06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acrocarpospora macrocephala|TrEMBL
MDLCFPGQACNLWGMSLGLPSRLPDRVPTVKDLLAAGERSFSFEFFPPKTDEGERQLWRA
IRELEALRPTFVSVTYGAGGGNRDHTVSIVERLAHSTTLTPVAHFTAVNHSIRELRHLVG
RFADAGVRNILAVRGDPPGDPMGTWVRHPEGVEYAEDLVRLIRQSGEFCVGVAAFPYKHP
RSATIESDTEQFVRKCRAGADYAITQMFFKADDYLRLRDRVAAKGCYTPIIPGIMPVTQM
STIARSEQLSGAPFPPEVAARFEAVAHDPESVRRLGIEHAAELCQTLLDEGAPGIHFITF
NRSSATREVFQALVPAIV
>A0A7Y3DMN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKLKDALNKKKFVVTSEVQAPIDQEPEDLVRSLSQVRGRVDGVSLSEVEFEGIVGDTIKT
CELLNKSLLEPIYQTTTRDKNRLQLQKDLVDAHQAGIDNLLVFTEDYRITGDSLQEMMFF
HVDAGKLQSVLEHIKEGQTVEGDTLSTKADFLLGSGVESSWGKNVPDLEMTEMEEMTKLG
TGYFLTTPVFDVDQFANFLKKAETFGVPVIAEVMILRTAGMARFLNRHLKSGLVPEWITQ
KLAQAANKQKASIEIFTDIVTGLKDLCQGVHIITIGGEEKLKLYLDAAKLK
>A0A7C4MYP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MSFQKRLASGEFVILAQMNTPKGVNISEMVNNARRIKERVHGVIIPDMDNGVMRMSAFAG
GVLMRQQGLEPVMHVYGRDKNRMALQGDILAAYVLGIQNLVVVRGEGMAAGDHVQAKPVD
DLDELSLLRVIRSLEKGTDMAGFELDGNPSFTVGCTFGAYVDDQTLDQEMEKARQKIEAG
AQFILTPAVFDMDRFASFLSKAKGLGVPIIPTVFLLKTVGIARYMATYEPGAFIPEHLIK
RMRQSKNREMEGFVIAGETIKHLKNLVQGVQIVTLGWEHRLPTILDYAEL
>A0A4V3D4I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiopseudomonas denitrificans|TrEMBL
MSKQRFSFEFFPTKTEAGHEKLLATAKELAGYKPEFFSCTYGAGGSTRDRTLNTVLQLDK
DTGIPTAPHLSCVGDSKQELRELLNLYKDNGIKRIVALRGDLPSGMGMANGELRYANELV
EFIREETGNHFFIEVAAYPEMHPQARNFEDDLQNFVRKVQAGANSAITQYFFNADCYFYF
VDRVRRLGVDIPIVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSDSIQAFGT
ETISKMCEQLLQGGAPGLHFYTLNQSIPSLAIWNNLQLSQRQ
>A0A1V3JIF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter genomosp. 2|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMENLLWESIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAINQETGLEAAPHLTGIDATTEELKKIAQDYWDSGIRRIVALRGDEP
KGYDKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHIIT
QFFFDIDSYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPNWLTKAYDGL
DDDPTTRNLVAASVAMDMVKILSSEGVSDFHFYTLNRSELTYAICHMLGVRPSV
>A0A5Q3LAL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetales bacterium 10988|TrEMBL
MKISEAYGPGKWGLSFELYPPKTAKSEKDLYQQLEKLAGFRPDFVTCTYGAGGSTREKTL
DIISEVKKRLGCPTASHLTCVCATVDDLREYLKEASKRGIENIVALRGDPPQGETEFKAT
ANGLRYANELVALIREEFPEFGIAVAGYPEPHREAPSAEIDLDNLKRKVGAGADAVVTQL
FYKNENFFEFRDRYEACGIKAPLIPGILPITNLAQIKRIASLCGAYLPPELLTSLEKYAD
DPEGQFKVGVEFATKQVQELVDQGVPGMHFYVLNKSKATAEVLDALSLPQRLRKLAG
>A0A3F3HWU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructobacillus fructosus KCTC 3544|TrEMBL
MDVSELFKNKTVFSIEIFPPKTALGREKLMTSLLEIRDIQPDFISITQSAAACFNEQRTL
AIAQAIQQKLGIATIAHVPCLYRTKEEVKDYLTDLEAAGVQNILALRGDAGNQQICPRDF
TYASDLINFINRNGHFDISAAAYPQKHPESSDVVSDTLHLKEKVQAGAKHLITQMVFDNQ
DYWEFKERLALADIHVPVEVGILPCTNSRQIKRITKMSGIKLPKKFLAITERYADDPVAM
RDAGLAYAIDQIVDLIANGVDGIHLYTMNNMENTRHIWNAIKNLLPDQTVSQSQCTFVEK
ERVRG
>A0A1H7Y1Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter sp. UNCMF331Sha3.1|TrEMBL
MPAISFEFFPPKTDEQREQLDTAVDRLKGHAPDYVSVTFGAGGSTLSYTDETVRRLRAEH
ALSVAPHLSCMGGTRAEIGALLDTYKVSGCRRIVALRGDLPSGMASPGDFRYAAELVGFI
REHSGDHFHIEVAAYPETHPQAENALADLRHFKAKVDAGADGAITQYFFNPDAYFRFVDD
VAKLGVTIPIVPGIMPIANFSQLRRFSEQCGAEIPRWIVKRMQAHADDAAAVRELGADVV
AELCQRLLDGGAPGLHFYTINRARATTSVLERLAAG
>A0A2E1AX68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda sp|TrEMBL
MKITEHIKKAGGKTLFSFEIVPPVKGKSIQELYKNIDPLMEFKPPFIDVTTSREEYIYKE
KDGLLDKKLTRTRPGTLGICASLKHKYDVDTVPHVLCGGFTKEETEYLLVDCQYLEIENV
MALRGDARKEERYFTPTKGGHRYASELVKQINDINHGNYLHDSIESSDCGDFCIGVAGYP
EKHMEAPSLQSDLKRLKEKVDLGADYVVTQMFFDNQKFFEFVKAAREMGIDVPIIPGIKP
IAVKKHLQLLPQVFRVDIPQDLINAVEACKDNKEVRQVGIEWAIQQSKELKEAGVPVLHY
YSMGKSDNIKAIAKELF
>A0A258Q014|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp. 35-63-240|TrEMBL
DVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIRSFGLDVVTDLCDQ
LITAGVPGIHFYTMNQAGATGEIMARLQQRR
>A0A0Q7PUM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. Root494|TrEMBL
MPAISFEFYPPKTDEQRAQLDKTAAKLKSRKPQYVSCTFGAGGSTLSYTPETIERLQAHH
GLEAAPHLSCVGGTRAELGELLLRYKAMGCRRIVALRGDLPSGMGQSGDFRYASDLVEFI
RTEYDGFFHIEVAAYPECHPQADDALADLRHFRRKVDAGANGAITQYFYNADAYFRFVDD
VRSLGMDIPIVPGIMPISNFTQLRRFSEACGAEIPRWIGKRMQAFGDDVDSVREFASDFV
AGLCQRLIDGGAPGLHFYTLNLSKPTLGVLSRLG
>A0A6A5TMV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Byssothecium circinans|TrEMBL
MMERITDKINALPEGANYFSLEFFPPKTQMGFANLQSRLERMSQALRPLFVTVTWGAGGS
TATKSLELAEICQRQLGLTTCLHLTCTNMSRSLIDEALEQAKVLGIRNILALRGDAPRSE
EYRDEDQAPEEDSNKDFTWAIDLVRYIRSQYGDYFCVGVAAYPEGHSDESHPEHQDPMSD
LPYLVEKTKAGADFIMTQLFFDEEAYEKWEKMLREHESGVFKTIPIIPGLLPIQSYQILR
RVTKLSHAKLPADILARLDAVRTDDDLVKQVGIKILSEIVEKLKKVPSPARRGFHFYTLN
LEKAVSHILEDCNLIPQPLFEDEEAIESTPAINLAPPDGAQSIKDRRRLSSVNSGPHNRV
IISRPSASKSSNPSYEALETEVGGLQGPINTRANTLAISEGEGSLGREATWDDYPNGRWG
DARSAAFGEIDGYGPTLHVSTAQALKIWGYPVERDDVSKLFRRHIEGDLEAIPWSEQGLL
PETSTISAELLALNSKGWWTVASQPAVNGLPSTDPVFGWGPRNGFVFQKPFVEFFISSAD
WKALQPRLKAHEQITYFASNAKGDFEASSEHGVNPVTWGTFAGKEIVTPTIIEGVSFRSW
CEEAYSIWREWRRIYPTKSKSSRLLGELREDMWLVNVIWGDYVEGDGLWKFLLE
>A0A428KZ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus canaveralius|TrEMBL
MSFLKKMENQILIADGAMGTLLYSYGTDCCFEELNLSEPEQILNIHKAYINAGADLIQTN
TYAANYLKLQRYGLEDSVKEINSAAVKVARNAAQDKAYVLGTIGGNRGIKPHSISIEEIK
RSFREQLYCLLLAGVDGLLLETYYDLKELETVLSIARRETALPIIAQVSLQETGILQDRT
PINEAFERLELAGADIIGLNCRLGPHHMLLTLEQVALPKHAYLSAYPNASLPAYVDGKFH
YEGDAEYFRKSAQPFREQGVRLLGGCCGTTPEHVRAFAEELKDKAPVTNKIVKLKEKKII
VETAIVKREEPPLDHVVKQRRSVIVELDPPRKLNTGKFFEGAKALQDAGIDAITLADNSL
ATPRIANEALGHLVKQKLGLRPLIHITCRDRNIIGLQSHLMGLYTLGLHDVLAVTGDPAR
VGDFPGASSVYDMSSFELIQMIKQLNEGLSISGKELGQKTAFSVGGAFNPHVRSLDKAVK
RLEKKIACGADYFISQPVFSEEKLIEIHDATEHIEAPIYIGIMPLISSKNAEYLHNEVPG
IKISESIRERMARFKDLPADASREGLEISKSLIDAALELFNGIYLITPFLRYELTVELTN
YARRHHNALTGRNDHVQTNIL
>A0A6P2GXW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia aenigmatica|TrEMBL
MSSLKQALNEGRFVCVLEVVPQQSPSRLTAFEQIVQRGHLAGWPLLPSFADRVGLHSDMS
PLDGAGALGNPATSLLHFSGKDRERADLLRQIESMRARGLEQLLLLSGDRLPGHHPGQAP
VRYLESVPALQIAREQCPDWLLGAALNPFKYREEEGGAQYLKAQKKLLAGADFFTLQLGF
DAAKHVEAQTWMRAQVRMKPMLACVMRLTDKRAAALQTVPGVVITESMRELLGREQRVSQ
AYASARSLERLTLQIVGLQLMDYAGAHVSGVHTLDELLALEQAITEQRDSVTSLTEWDER
WRASWQMPGAPQVCFAPEIDAWEMGQSDVTATRRERLRHTLLSTAHSQVFGGTGWLSRAF
GWSVTRPIWKIGVAADALHAVERTVKRPLVGCDTCGSCRLHDTLYVCPETCPKGLANGPC
GGTRLNRCEFGDRECVHSVKYRIAKSANQLPVLAQTLIPCIEAGNRHRSSWPEWFEPEES
TPGR
>A0A2C5HJ51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia aryabhattai|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINVAGVKLAKQAANDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLNEGVDGLLFETYYDFEELKTVLTLARKETDKPIITHVSLHDIGVLQDGR
PLADALKELEDLGADVVGLNCRLGPYHMIQSLEEVPLPDRAFLSAYPNASLPAYVEGKLE
YETNEDYFVESARLFREQGVRLIGGCCGTTPAHVRAMSSALKDLPPITSKVVKMRPAVTV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRIRGEVEGLAIAKNLIDTAYELFDGIYLITPFMRYEMTEILTRYI
HDKQLVTSERKI
>A0A838KBF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporichthyaceae bacterium|TrEMBL
MPGKAAEEADSGVLSATTQTQPGAVWGAAAVKRFSTHGKTEPSVGTLTDPTSADSPENRQ
RQALVGLLRQPRYEVLPLAGTADIVEQHVPLTLPVTVTASPRKGLEPTITLAEGLARGGF
TAVPHLAARLVYDEAHLSEIMCRLDDSGVRDVFVVGGDGETPVGDFADSLQLLSAMKRLR
QTDSGRSLQAVGVAGYPEGHPRVSQDELDRALLEKQPLSSYIVTQMCFDAGAVHGWIGHA
RALGVRLPVHAGIAGAVDRLKLMRIAGRIGVGTSLRFLRKQEGGARLLRSGGFRPDRLLD
ELTSGGELAMDGLHVYTLGDVETTERWRRELLDRLTDGGGHG
>A0A228IAG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia aenigmatica|TrEMBL
MSSLKQALNEGRFVCVLEVVPQQSPSRLTALEQIVQRGHLAGWPLLPSFADRVGLHSDMS
PLEGAGALGNPATSLLHFSGKDRERADLLRQIESMKARGLEQLLLLSGDRLPGHHPGQGP
VRYLESVPALQIAREQCPDWLLGAALNPFKYREEEGGAQYLKAQKKLLAGADFFTLQLGF
DAAKHVEAQTWMRAQVRMKPMLACVMRLTDKRAAALQTVPGVVITESMRALLGREQQVSQ
AYASARSLERLALQIVGLQLMGYAGAHVSGVHTLDELLALEQAITEQRDSVTSLTEWDER
WRASWQMPGAPEVCFAPEIDAWEMGQSDVTATRRERLRHTLLSTAHSQVFGGTGWLSRAF
GWSVTRPIWKIGVAADALHAVERTVKRPLVGCDTCGSCRLHDTLYVCPETCPKGLANGPC
GGTRLNRCEFGDRECVHSVKYRIAKSANQLPVLAQTLIPCIEAGNRHRSSWPEWFEPEES
TPER
>A0A510TL24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 1-11|TrEMBL
MRDILAAGKTTYSFEFYAPKTPQGERNLWNALRRVEAVAPDFVSVTYGAGGTTRTTTVRE
TQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVRGDPAGDPMGEWVPHP
QGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVRHFVDKCRAGADYAITQMFF
QPESYLRLRDRVAAAGCETPVIPEILPVTSVRMLERVPKLSTALFPDALKERILTAKDDP
AAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>A0A1Q3X9U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus sp. 65-1402|TrEMBL
IRDILNEYKSQGIRHLVALRGDLPSGSMDVGEFQYANELVEFIRKETGDWFEIEVAAYPE
VHPQARSYAEDMINFKRKVDAGANAAITQYFFNADAYFGFVEDARAHGVSIPIVPGIMPI
GNYVQLARFSDACGAEIPRWLRKKLESYGDDLASIRAFGLDVVTDLCDRLLAGGAPGLHF
YTMNQAGPSTVIWQRLGL
>A0A0Q8R2W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noviherbaspirillum sp. Root189|TrEMBL
MTQKNFSIEFYPPKTPEGVEKLRITRAKLAELQPKYFSVTFGAGGSTQRGTLETVLDIQR
EGHEAAPHLSCIGSSRDSLRAILNEYKANGIRRLVALRGDLPSGYGASGEFRYANELVEF
IRAETGDWFHIEVAAYPETHPQAKSPQDDVQSFVRKVNAGANAAITQYFYNADAYFRFVD
DARKAGADVPIVAGIMPITNYSQLMRFSDMCGAEIPRWIRLKLASYGDDTESIKAFGLDV
VTGLCERLLAGGAPGMHFYTLNQAAATTALWKRLNLSA
>C3PE90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CIP 107346 / CN-1)|TrEMBL
MSPRLSASAPLDQISEDTPKELKRTALSFEVIPPRHDADAAKIDRLLATLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTEEELVGWIDTLVDAGVRGLLALR
GDLPEGGMPEGHLPHADSLVRLIRRWESDRVARLAAGRLAVGVACYPNGHAESATPDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLAGPTKVLDQLAAATSPEEEKEIGMQITASLAKSVMNAGADGLHIYTHNNPDITTDLL
NRIGVTP
>A0A510TBV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 1-11|TrEMBL
MNPRPAAPPAVSASLLDDFSLEMTGKDVPKLQEARHSIPPGTRINVTFLAGEDLATRLAA
ARAVKSLGFVPVPHISARRLPSRAHLEEFLAGLAADGTAENVFVVGGDPARPEGPYPDAL
SVIRTGLLQRHGVRHIGISGYPEGHPAITEGTLWSALTDKSAVLGAERLAGDVITQFGFD
VDPVLGWLEAVRARGVALPVRIGVPGPAGVRRLMAYATRFGVATSASVARKYGFSLTNLI
GTAGPDRFLHALARHHDPARHGRVKVHFYTFGGLRATSEWIARFRHGERADRRP
>A0A1I5MG64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. PDC80|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAARQQLYARKPEFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRETVRAQLAELKAMGVKRLVALRGDLPSGYGAGGEFQYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVKAGADSAITQYFFSADAYFRFVDE
ARALGIDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIKAFGLDVV
TDLCARLREGGVPALHFYTMNQSAATLAVLERLD
>A0A2X4V3A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia plymuthica|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLDAAPHLTCIDASPAQLREIATDYWNNGIRHIVALRGD
LPPGGGKPDMYATDLVKLLKEVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAA
>A0A0Q8KLF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. Root172|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILNETNLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A1X9NDT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanicoccus sagamiensis|TrEMBL
MSENKRFSFEFFPPKTDVGREKLATVRKELNQLGPDFFSVTYGAGGSTRDNTKDIVLTMT
DEGISTAPHLSFGGDDEASMLELITSYKEAGINRIVALRGDMPSGMGAQRLIYAEELVQF
IRKHTGDHFHLEVAAYPEIHPDADNYDSDIQFLKQKFDAGADSAITQYFYNADAYFYFMD
QCQKIGIDKPIYAGIMPITNYQNLARFSKNCGAEIPRWVCQKLEGYGDDKESIAAFGTDV
VTKLCEQLLANGAPGIHFYTMNQIEPNKAIWNNLKL
>A0A518EQ13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium Poly30|TrEMBL
MTAGQRIAEIYASGKPVFSFEFFPPKTDQGAENLMRTAADLKESVEPDFISVTYGAGGTT
RDRTHSVVTQIQDDLGITGLAHLTCVGASSEEIQSVVQRLEDAGVRNVLALRGDPPEGAE
RFEVHEGGFGHATDLIAFLQENHDVCIGGACYPESHPEATSAEEDLRFAKAKQDAGADFL
TTQLFFDDRLYLAFVERARAAGITIPIVPGIMPITNVAQIQRFTKMCGASLPEKLLDRLR
PVQDDPAAVMATGIEFAITQCRELLEKGAPGIHFYTLNKSHATRSVLAALR
>A0A854E6E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. MB339|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RTEHGDAFHIEVGAYPETHPQATDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWIGRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLRG
>A0A6A6FWZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cercospora zeae-maydis SCOH1-5|TrEMBL
MHITEKLQQAHGKGKATCSFEYFPPKTAQGVQNLYDRMDMMHGLGPAFVDITWGAGGRHS
SLTCEMVKVAQTAYGLETCMHLTCTDMERSKIDDALKEAYKAGCTNILALRGDPPREQEK
WEATEGGFRYAKDLITYIKKTYGNHFDIGVAGYPEGVDETCGADEHILYLKEKIEAGGTF
VVTQMCYDADIFIDWVKKCRAAGIPESVPIIPGIMPISTYAAFLRRANWTKAHIPEQWLE
KLEPIKNDDSAVRAVGCDLIVEFCQRLLDFGLMHLHFYTMNLAQAVKMVLEKLDMIPEAE
SPHPDIKPLPWRQSLGLNRREENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
GLDEYGIGLKGTNEHNRKIWGEPKSIQDIAQLFVGYMSGKVESLPWSEAPINDEANTLVN
DLVQLNSRGLLTINSQPAVDGVKSSHPTYGWGPRNGYVYQKQYLEVLVSPALIDTVIARM
NRDPEITYYAVNCNGELKTNAPPDGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYH
LGLEWSKCYEEGSESRKIIREVTQNWYLVNIVHNDFRQQRGIFPIFDGLKAPGLEPAEVN
GVNGHAETNGVPPETNGVPDGNNAVNGADKVASSNSAQTA
>A0A7S3LLF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aplanochytrium stocchinoi|TrEMBL
MAAMTSLDVFKIPGKVCEKTSEKPFIAFEYYPPKTETGVENLMKRMKRMKELGPLYVDVT
WGAGGTTSDLTMDLCDRAQKEFGLVANMHLTCTNMPREKIDEAIRVAKEKDIKNILALRG
DPPIGQKDWKPVESGFSCALDLIKYLREKAGDFFAITVAAYPEGHPTRIKKVEEGHALSE
TEKGRCVTLEDGVYVCSDKDFQEELEYLKKKVDAGAGMIVTQMFYDVDCFLAFVNACREY
GITIPIIPGVMCVTSYGGFKRMGQLCKTRVPKDVAEMFESVKDDPHKVKQAGIHLGLQMS
KKLLDSGIQGLHFYTLNLEDVVEGILKGLDMVESKDSENASEDN
>A0A836LSW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 6112|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A6I1VQ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FSL R10-0071|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDINNFVRKAHAGADSAITQYFFNADSYFR
FVERVQAAGVMIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A6A6TE63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lophiostoma macrostomum CBS 122681|TrEMBL
MEKITDKIKALPDGANYFSLEFFPPKTSMGFANLQTRLERMSRALRPLFVTVTWGAGGST
ATKSLELAEMCQRQLGLTTCLHLTCTNMNRSLVDDALEQARALGVRNILALRGDAPRSEE
YRDEGQSPDEDSNKDFTWAIDLVRYIRKQYGDYFCVGVAAYPEGHADESHPDHQDPLFDL
PYLVEKTRAGADFIMTQLFFDVNAFDKFEKMLREHESGVFKTIPIIPGLMPIQSYQILRR
TTKLSHASLPDDILRRLDAVKGDDELVKKVGVQIISELVEHIKPRPSPARRGFHFYTLNL
EKAVSHILEDCKLIQPTFEDEDEEAVFSELDPPGITISPPKAALNRERRRLSSVNSSPHN
RVIVSRPSKSSNTSFEASESEAGIPKSAINNRANTLAISEGEGSLGREATWDDYPNGRWG
DARSPAFGEIDGYGPTLHVSTAQALRLWGHPVEVEDISTLFRRHIRGELEAIPWSEQGLS
PETSTISRELLALNAKGWWTVASQPAVNGLNSTNPVFGWGPKNGFVFQKPFVEFFLPGKD
WEKLQPRLDEHDQITYFAGNAHGDFESSNEESVNPVTWGTFAGKEIVTPTIIEAVSFRSW
QEEAYSIWREWQRIYPTRSQTNKLLGSCREDFWLVNVIWGDFVEGQGLWEFLLE
>Q063K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. BL107|TrEMBL
MLAMAAYLQGRVHALNVTDGSRAVMRMSSVAACKLLIEAGAEPVLQLACRDRNRIALQAD
LLGAHALGIRNLLCLTGDPVRSGDQPLARPVNEFESVKLLQQVEALNQGEDPVKGNLPDG
ATALFAGCAADPHSRSWSGLQRRLQRKAGAGARFVQTQMVMAPQVLDRFQRELAGPLQLP
VLAGVFLLKSAKNALFINRVVPGACIPDHLIQRLDAASDPAMEGVAIAAEQVRTYLGIVQ
GVHLMAIKAEERIPLILDQANISSLTT
>A0A2V2FH30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKITALLAENKPILSFEVFPPKTESGFDSVRTATEEIAALHPAFMSVTYGAGGGTSAYTL
DIAENIKARYGVPTLAHLTCVSSTHETVRERIAAIRSRGIENVMALRGDVPPELRDADRS
GWDYHYAAELVRELRAAAPDLCIGGACYPEVHPESRSQAEDIRRLKEKVDAGCDFLTTQM
FFDNNLLYSFLYKIREAGITVPVIAGIMPITNCSYLTRAIELSGSFMPRRFVSLVDRFGD
DPAAMKQAGIAYATDQIIDLYANGITGVHVYSMNKPDIAAEILGNLSAILGR
>A0A356AML2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MYISHLYQKNATVLSFEVFPPKKDSDIESIDGVLKDFADLHPDFMSVTYGAGGSAQTVSR
SKKLADKIENTFHIPALFHLTCIGADKNRLGELLLQLRQMKIQNILALRGDFPGDGSGTG
DYTHACDLIRQIKEEGGFCVGAACYPEGHIDCESPELDREYLKRKQEAGADFFISQLFFE
NRYFFRFLNDARKNGITVPISAGIMPILSRNQIERMIFMCGASLPGSIVKLLHRYGDNPA
DLRKAGIEYAVCQAEDLIANGADGVHLYTMNHPDIARSAMWRFRREKTANHE
>A0A3D2AA14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
KDKLDYRHATDLIKEIKSIAPEFTVGGACYPEIHPESANQKEDIRYLKEKVDCGCEFLTT
QMFFDNNLLYNFMYKIREAGITVPIVAGIMPITNANQVERAIKLSGSLMPQRFKSIVDKF
GYDPDAMKQAGIAYATDQIIDLFANNITNVHVYSMNKPDVAEKIEANLSAIIGK
>A0A502WD79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-8-4|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>C3LSB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cholerae serotype O1 (strain M66-2)|TrEMBL
MTLGHREYKMGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKTLQ
PKFVSVTYGANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQ
NIVALRGDIPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRK
VDAGANRAITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVP
NWMVKQFEGLEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGV
RPQA
>A0A4S9C6U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNNNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEVTAPQAPQ
IVNGATNGEKHEEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A1G8AM79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrococcus jejuensis|TrEMBL
MSHCLPFSFELFPPRDASATDTLDDSLARLVAAGPSFVSVTYGASGSTRDGSLAVLRQLL
AADARPMAHLTCVGLTVREASVLVRDFLDAGITRFLALRGDPPVDGAPLGDLGSASELVQ
LIQRVEAERAPYREIGREGRSVVAERPRAVEVAVAAFPNGHPGSGAGSARHDVDALLAKQ
AAGATLAITQLFFDPYDYERFVDLARSRGITIPIVPGIIIPDSARRLVRAAELANERPPA
ALLAALDGASPEDAERIGIDATVALVDELRHLAPSVHLYTFNRHRAALEVLRGVGSIAGA
SA
>E3J1M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia inefficax (strain DSM 45817 / CECT 9037 / EuI1c)|TrEMBL
MFPGGDPTPDAGGHRGGLRGDGGHQRVPRVRGPDVRALRDEQSLGQQLVDSGADVGRIGL
EGPVNPSGPGAGNSHGPPAPAVAARLAVAVAGGRIVAPYPVRVQESTAGHERPERGFELI
CEIEPPTRPDLTHARHQIGVLSPVTDAFLIPDNHIGRATVSSIAVAHEVATMGGRSIACV
NSRDRNLLGFRRDLLTAAAYGVEEFLFVHGDKPTAGNRTSDLTVRAMMDEARAASADPVF
ADTPAFRVGAAAGLRPLPTWKRAADFLFVQVSYSVDALLRWRDAHPVELPVYAGVMVLAS
AGMARRLAATIPDIDIPDDLVQAVERDRAAGVEAACDQVLRLRDSGAFAGVHLVPVSRYR
QVATRLEDLL
>A0A2H9VPN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter auburnensis|TrEMBL
MKITDHIAKANGKTLFSFELLPPMKGQGIQGIFNAIDPLMEFNPPFIDVTSSREEYVYKE
HANGLLEKVSYRKRPGTVAVCAAIMNKYGVDAVPHLICGGFTKEETEYALIDLQFLGIEN
VLVLRGDARKTESSFVPTQGGHCYANELLEQVVNMNNGKYLHEDHEAVKSDFCIGVAGYP
EKHFEAPNLKTDFKYLKQKIDAGADFIVTQMFYDNSKYMEFVKQCRENGINVPIIPGLKP
ITSSKQLINLPKIFHIDIPDELSDAVHACKSEADVKEVGIEWMINQCKELMKFGAPVMHF
YTMGNPGPTKRIAQAIF
>A0A4R8I8L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epilithonimonas xixisoli|TrEMBL
MKIIDHIKSANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFNPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEQSKGGHKYASDLVKQIHDLGIGEYLHGKIESDTDNSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKFFEFVKQAREIGIDVPIIPGIK
PIATKTHLQMLPQVFKIDLPEALINEVLKCKTNNDVREVGIEWAINQSKELLDFGIPVLH
FYSMGKSDNILKIGREVF
>A0A1F9NVP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula sp. RIFOXYA12_FULL_46_16|TrEMBL
MKTESKLERILASGNLAVTSECGPPRGARPEKVREKAALLKDHVDAVNVTDNQTAMVRMS
SWAAGVIIKQMGMDPILQMVTRDRNRLAMQSDIIGAYSLGINTMLCLSGDHPKFGDHAAA
KSVYDLDSVQLVRMVQKMRDEGKFQGGADIDCPPKMFVGAASNPFAEPFDLRVSRLAKKI
KAGADFVQTQCIFNLDKFEKFMEMVCDRGLNEKVYLLAGITPMKSAGMAKYMKNKVPGMD
VPDEVIKRLEGVSKAEQPEEGIKIAVESIQRLKEVKGVHGFHIMAIEWEEKVPQIVEKAG
LFPRPAVENL
>A0A4S9R3B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MDRVHLFVFFILFFIAKRLISRHRQVNRRAAAKEKKATYSFEFFPPKTAQGVQNLYDRMD
RMHNFGPSFIDITWGAGGRHASLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEA
HDAGCTNILALRGDPPREKEKWEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDD
NDNPEELIQHLKEKVDLGGTFIVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHA
AFLRRANWSNIHVPPHWHEALEPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMN
LAQSTRMILEELSITPSQDTPLEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDW
DEFPNGRWGDSRSPAYGELDTYGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVES
LPWSESPITDEADALRKDLINLNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAY
LEVLVSPELISELITRMERNPNITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPT
IVETVSFLAWRDEFYRLGSDWSRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFP
LFDELEVPDLNKEITAPEAPQKVNGATNGEKHQEEPKVGNGDVTDSKIPDSVHKKLETQI
NGAEEKPDTEPKDATAHNTGAGPSTSV
>A0A7S6YLS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. Ac-14|TrEMBL
MSHLSPCFQQNQFFVLVEYLTSLHEIYPVRREFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEFFLEQAKSANVQNLLLLTGDKLKEHHNGRDGQLRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHVGFSGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
SGKEFSPEITYFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGLGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVAQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A7Y2Z8K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp|TrEMBL
MKSGSNLEKVLAAGHFAVTAECGPPRGANPNKVLEKAEHVKGNVDACNVTDNQTSVVRMS
SLAGCILVKESGTEPLLQMVVRDRNRIAIQSDLLGASALGVRNLLCLSGDHQKFGDDPQA
KNVFDIDSIQLIYLAKMMRDEGIFPSGDKLEGAPKFYIGCAVNPFADPYEIRVARLKLKV
DAGADFVQTQCIYNMDIFKQYMEDAKKQGLHERVKILAGVTPLKSAGMAKFMNRMVAGID
IPEDVIKRIADEPKEKQAAKGIEMCIEQIQEVKEMEGIAGAHVMAIEWEEKLNEIIGGAG
LLPRPAVEQ
>A0A2P6V4G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micractinium conductrix|TrEMBL
MPGAKIIDKLNERVSAGQTFFSFEYFPPKTDEGVANLKERQMRMAALGPAFCDITWGAGG
STADVTLDVARSMQQEVGVETMMHLTCTNMPVDQLQEALAKAKEYGIRNILALRGDPPKG
QDHFEQVEGGFACALDLVKYIRAEHGDYFGIGVSGYPEAHPDVIVEDAAQMEKNYWVDID
YLKQKIDAGADFVVTQLFYDVDRYFKFVKDCRSRGIHCPILPGVMPIMAYGGFKRMTSFC
KTAVPQHMADTLEAIKGSDEAVKAFGISLGTMMCQRLLDGGAPGLHMYTLNLERSAVAIL
ENVGLIPKAPKQLAAADGVA
>A0A8F8ATF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella bongori|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1F9ZGZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon RBG_16_68_12|TrEMBL
MKSGSRLERVLLSKRFAVTAEIVPPASPDPSGVLATARRFRGYADAFNVTDSPRASVRMA
GWAASVLLLREGLEPVLQVTTRDRNRIALQADALGAAALGIKNVVCMGGDDPKTGGESAA
TRVHDLRTEELIETLRDLRDRGVLRGGDPVQARPALFIGATANPFGGPVEDSFANLRGKA
EAGADFVQTQGIYDVEAFEEWMHLVRKEWLHEKVHILAGVIPLRSARTARVIAERLPGVR
VPPQVIARLESASDPKAEGIRIAVESVEALRKVEGVHGVHLMAVGWEDAIPSVVKGAGLL
PRPSA
>A0A1Q7UK71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium 13_1_20CM_4_68_9|TrEMBL
MPHAFDRRLAAGPLLCDGAMGTLLYARGVSIDACFDVLNVSQAKVVQSVHSEYIAAGADC
IETNTFGANRFKLAVHGLASDVHQINLRGVKLARDVRESMGRDVLVLGSVGPLGKYLAPL
GTVTADEARAAFREQAEALLEGGIDAFVVETFSDLTEIALAIETIRTLTDLPIVAQMAFT
DEGVTFAGRSPAEVARTLRELGVRALGANCSVGSSTLYEVLEAMGPEARDVPLAIQPNAG
LPHRIGERLMYLSSPGYMADYAGRMIDAGARIVGGCCGTTPQHIAAMRRVLDARAPASKA
EPRPTSAARVIEALETPGLRTTLAPTLLGRKLEQRSFVVSVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLPTAILVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALGIRNILAMTGDPPRTGDYVNATAVFDVDGIGLLEVLRRMNEGMDATGNGIGEPTSFCV
GAALDPGAPDPGREVERFHRKLEAGARWFQTQPVYDLEVLDRFLARVVGSPVPVLVGVLP
LHSFRHAEFLHNEVPGITIPDGVRARLRAAGDGALRAGIDMAQQLVGEIRSRYAGAYLMP
SFGRFEVVAEVLDVLR
>A0A2N2MX47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-4|TrEMBL
MPGFTPARRWQQAYYPFKNRTVGQKIEEALERTIKGALFGCRMCGNCLLQETALICPMEC
PKGLRNGPCGGSTPEHCYVDETRPCVWFKIYERAEKYGRLDVLMEVLPPLDWDKVGTSPQ
PDGWNNLRKHGGIQAISRYLRSTPEIRKQKWEHFFKEIRQPDWWQGDALPHPAPLHVPVS
HLEQLLSDGKFAITAEIAPPLSASPDDLVKKILMLKECVDAVNFTDNPSSTPRMSSLACS
LIALQNGVEPVLQIAARDRTRMGLQGEVLGASALGIRNILCLTGDHPRLGPGPNGRMDIW
DIDAIQAMWIIRRMRDEAQFLDCREIKCAPQVFIGAAGSPYASTPLIQAMREEKKVNAGA
QFMQTNLIFDYDGFKQYLEALERRDVTQRVPILAGISPIRSVKAAHAMRQVPGVKIPDAI
IQRMEASADPKEESVQITLELIDKVKTLPGVRGIHFMAVGWESIVPRLIKDSGLR
>A0A0R1PFN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus kefiranofaciens subsp. kefirgranum DSM 10550 = JCM 8572|TrEMBL
MSLTALFKNKTVFSLEVVPPKKDSPKEAILPTLQQLQSINPDFISVTLGAGGSDHYTGTV
QITDLIQNQLNIPAVAHVPGLYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDF
NHANDLVAFVHQNRPDFSIASACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDN
QAFYDFQEKAEIAGIHVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSKEA
MREAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWNATKSVFDAANARTWTTIA
>A0A1I2K1R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces mirabilis|TrEMBL
MDSVSTAAASAVAPLLDDFSLEMTGKDVPKLEEARGTIPQGTRINVTFLGNEDLDMRLDA
ARAVKRLGFVPVPHISARRLPSRAALEEFLAALEADGLADNVLVVGGDPAEPHGPYDDAL
ALIRSGLLQKHGVRHVGVSGYPEGHPAIADPVLWSAMEHKSAALEEHGLPGAVITQFGFD
VDAVLAWVEAVRARGIDLPVRIGVPGPAGIRRLMTYAARFGVGTSTSIARKYGFSLTNLM
GTAGPDRFIRALAKGFEARRHGELKLHFYTFGGLRTTSEWVADFRDKEN
>A0A2W2C268|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora endophytica (Xie et al. 2001) Li et al. 2019|TrEMBL
MALGLPSILPNQHPAIGELVRTSPQTFSFEFMPPKTEQGERQLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERVATETTLVPMAHLTAVNHSVAELRHVIGRLAGAGVRNVLAVR
GDPPGDPTGEWVPHPEGVHYAEDLVRLVRQSGDFSVGVAAFPYRHPRSPDVATDTEYFVR
KCRAGAEFAITQMFFDADEYLRLRDRVAATGCDTPILAGVMPVTRIGTIERAVQLSGAPF
PPALAARFERVADDPEAIRQLGIEQTSEMCQRLLDEGVPGIHFITFNRSTATRQIWQNLR
VSAAT
>A0A417AT14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM43-3BH|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPELCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A1Y4NEL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeromassilibacillus sp. An172|TrEMBL
MNIADKFNKGKTVLSFEVFPPKKTSPVETIYGTLEKLVELRPDFISVTYGAGGSNVGHTV
EIASKLINDHKIDALAHLTCINSEKSHIDRVLEEFKAGGIENILALRGDIVPDKEPCHDF
KHASDLCSYIKEKGNFYLSGACYPEVHVDAADEVEDILNLKKKVDAGAEHLITQLFFDNN
AYYRFRERARIAGINVPVSAGIMPVVNKKQIEKMVSLCGASFPAKFSKIMAKYESNSEAL
RDAGIAYAVEQIVDLIASGAEGIHIYTMNNPYIAEKITSAIKNLL
>A0A5B8KUN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor sp. SY7|TrEMBL
MNQFRLSRRPDIGEKINVSFEFFPPKTDAMAARLWETTQRLEPLAPYFVSVTYGAGGSTR
ERTARTIERIIKETSLTPAAHLTCVDAKCDEVDGVIRQFLDLGVKRFVALRGDPAEGVGS
HYQPHPGGYASTADLVAALARHGAEDISVSAYPEKHPESPDYATDIDVLKRKVDSGAKRA
ITQFFFDNDVYERYVERVRRAGIYAPVVPGILPVHNFAQVANFAGRCGAHVPAWLAERFE
GLEDDPQTHMLVAAAVAAEQVLDLVERGVTDFHFYTMNRADLAIAICHMIGIRAQALVEE
EKPAAA
>A0A396A5J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM36-4AA|TrEMBL
MRVDEVFKQAASQGTTSVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A3R8WC39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. SC28|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYQNIDPLMEFNPPFIDVTTSREEYVFIE
RGNGLMERKITRMRPGTLGICAAIQHKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEPSKGGHKYASELVKQIHDLGTGKYLHEEIQCDDSSSFCIGVAGY
PEKHIEAPSMKYDLQMLKKKVDAGADYIVTQMFFDNQKYFDFVKQAREIGIDVPIIPGIK
PIATKTHLQLLPQVFNIDLPETLISEVLKCKTNNDVREVGVQWAISQCKELLDFGVPVLH
FYSMGKSDNILKIGRAVF
>A0A136L110|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium OLB14|TrEMBL
MPLFTPGRRYQPPFMPFKRLPFKKRLLTKIELAIKSPLFGCRMCGNCLLSKTALICPMEC
PKGLRNGPCGGSTPEKCYVDESRPCIWYKIYDRAFKLGREAHLLEVLPPMDWDKAGHDSW
SEIVSHAKDMGIKTILSHLNSGEVGSVSATVESIIQPIRQPEWWQGDSEYHAPKYTQPIS
ELEKKLKAGEFVVTTEIVPPLSINTDKLKRNINLLKNYASALNFTDNASAVPRMSSMACS
KISIDLGAEPIMQISARDKTRVGLQSDVIGASALGIRNFLCLTGDSMMMSPNPKGRMDIV
DFDSIQMLWILRRLRDEAKYLDGREIKNPPQYFLGAAATPFASNMKFQALREQKKVNAGA
QFFQTNVVFDADDLDNWLNEMLNATF
>A0A2D8URP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesonia sp|TrEMBL
MKVVDHIKKAKGKTLFSFEILPPLKGQNIQSIFDHIDPLMEFQPPFIDVTYHREEYVYKE
LSGGLLQKKVVRKRPGTVGICAAIQNKYEVDAVPHILCGGFTKEDTENFLIDLDFLGIDN
VLALRGDAVKNETYFSAEKEGHTFAKDLVKQIVGLNKGEYLDEELLNKSKTNFCIGVAGY
PEKHMEAPSLDQDVLRLKEKVAAGACYIVTQMFFDNQKYFEFVDKCRTAGITVPIIPGLK
PLATKRQLSILPHRFHVDLPDTLTLEVLKCKTKDQVRQVGVEWCIQQSRELISAGAPVLH
YYSMGKSNNIHKIASELF
>A0A0C2G6J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylostoma duodenale|TrEMBL
MDITVPIIPGIMPIMGYDSIRRIATLSQLTIPESILSDLEPIKHDDDAVRKYGTIKVSLL
LWNPYLEALC
>A0A8B9PNV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apteryx owenii|TrEMBL
MVVLAQTSLPFYLQSSAAHPSTYCSLVRSVFSLIPTVLLFLSTREFTMVNETQHTCSASS
SSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDKWFSLEFFPPRTAS
GAVNLTSRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIASTAVNYCGLETILHMTCC
NQTKDEITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVEGFNYAVDLVKHIRNEFDDYFD
ICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLKFMKDCQAIGITCP
IVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLD
SGMVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRP
KSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESV
FEVFTCYITGEPNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNINGK
PSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNYHIVNVKGQNITNA
PDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKLYEEESPSRMIIQY
IHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTH
>A0A0B7C506|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arion vulgaris|TrEMBL
DAGADFIITQLFFKPETFFNYIKDCREMGIKVPILPGILPIQAYQSLHHIVKLSKLVVPQ
DIIDTITPIQHNDEAIRKYGIDQSVDMCR
>A0A2H9LB51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Diapherotrites archaeon CG08_land_8_20_14_0_20_34_12|TrEMBL
FDLRGKKITDILAENRFTLSVEIVPLRNGKSYGEILGDIGKLSTLGIDFASVTKGAGGGL
RGGSLPLSYFITQRFGINSIAHFTCMERTKEQIETELVDYHLFGIKNILALRGDLPVGNN
SLNIKSDYEYAWQLVRQINSMNNGIYLKRAETEKGTGERTDFCIGVAAYPSAPNIDEQIA
YLAKKVDEGAEYALTQMIFDSSAYFNYLDKCKESGINIPIIPGIRPIVNRAQCEFSEKFF
GLKIPNELKNAVTVNDQAIARENGLEYAIGLCDELKRNGAPGLHLFVINDIKAACEIITS
LRKKEENAQFCRDFYHNPYKIN
>A0A7S0KI27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonas pusilla|TrEMBL
SDAGSARARVDARRHRGRIRSDVHQAGAPRECPIPAPDTSDGVPPSVGTDVVHANNRIPV
QPTPHPEPKAARVFLERSPYVSWRAQRPVFAHPAFNGVIHPDLPVWAGEPGIPEPAVGSD
AAAPRISRLAKTEVDILPDFHVQTIAASRCRSAAEARQRIAAASDAGASAILMVTGDAPG
GSSRRGSRRGSWDSTDLLREAGAMRERGEVHEDVTLACVANPSLEGAARDPTARLRAKLD
AGAEMVVTQPAMLAPATSRRWWDAARLRSLHRECDVVFGVAYLASWRSVRHWQRLCGLNG
DGSAGDVGGAGAEESDEVARLWEETERTMDLKTFQEWRDERLDLAVAAVLADEDAHGVHL
MPVTEEGYGAVARVADAIGALARPPSGAAREG
>A0A1G1DSS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium RIFCSPLOWO2_12_39_16|TrEMBL
VTDNQRGIMRMCSLAFSHLLKEIGHNPIMQVCTRDRNRLALQSDILGAGALGIENICIMT
GDHPKLGDHPDAKPVFDLDSIQLIQVIKEMETGVCMSGKRLESSAKFFVGGVANPFFEPF
ELELIKIKKKIDAGAEFFQTQPFFDKESLEKFLEEVRGLNTKFLIGISPIKSIKMINFLN
EKVLTKKIPENISKRVEAAENQTEEGIRIAAEFIRDIKGMVKSIHIMPIGIESYLPYLLD
EAEL
>A0A1F8MWZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_52_14|TrEMBL
MKQGFRETLKSGKFIITSEIGPPKGTNLDKMRHHIEILKDRVDGINVTDHQSSVMRFPSL
GGCLEIKEHDGEPILQMTCRDRNQMALQADLLLAYTRGIRNVLCLTGDAVPVGDHKQAKG
VFELDSVQLLRAIKQMESGKDMGGNDLDGAVEFCAGAIVTPEAKPIEPQLIKFEKKIEAG
AEFIQTQAIYDLDNFARFMKSARQYPVKILAGIVLLVSAKMAKYMNENVPGIFVPQNLID
ELASAPKGQALNKGIEIAGRMIKTIKDEKLCDGVHIMAIGKEEVVPDILAVAGLNGHV
>A0A2K4VMX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. avii|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1Z9G6A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceicoccaceae bacterium TMED149|TrEMBL
MKSASIRSKIQAGTLTLSLEFFPPKSETAAQQLLKTSEQLKVLNPDFVSITYGAGGSTRA
STLEYAETLKNTHHYEVMPHLTCVGHSQDELLKILKDYETNGIQTIMALRGDPPIGDQHF
TXHPEGFHYANELVQFIKAQCPDFEIGVGGYPEKHPEASDLETDIANLKKKVDAGASFIT
TQLFFNNEHYFRFVEQCQDAGIECPIIPGLMIPTNLERVERFCDFXGAELPQALKDALST
ASANQEPQALEAAAVEWTFQQVKGLLENGAPGIHMYIMNQSKFMLALYQKFKEANIAF
>A0A2E3XU73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovoraceae bacterium|TrEMBL
MKVIEHLEESKGKTTFSFEIVPPPRGKSVKSVVDIVEKLVPYNPPWIDVTAHSAGAFYNE
KKDGSVERRIYKKRPGTIGICGIIQNRFKIDTVTHLLCNGFTKEETEDALIELQYLGIHN
ILALRGDGLNYSKKIDRSRRVNQYAIDLVEQVEEMKQGRFLDELSGADPLEMCVGVAGYP
EKHFEAPNMKYDLGWLKKKVDAGAEYVTTQMFYDNKHYWSYVEQCRAEGIDVPIIPGIKI
LKSVRQLQSIPKHFYINFPDELVDEVMQNQDHVKEIGLRWAKKQVEDLVNNGVPCVHFYI
MNDTSSVIDVIKQFK
>A0A2S0N4X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Simplicispira suum|TrEMBL
MSFEYFPPKTPEGAEKLRTVRRQLQALAPEFCSVTYGAGGSTQQGTFETVREILQEGVAA
ASHFSCIGATRQSVREQLALLSAMGVQRLVALRGDLPSGYGMGGEFQYASDLVSFIRSET
GDAFHIEVAAYPEVHPQARSPEADLRAYVTKVQAGASSAITQYFYNADAYFRFVDDAARQ
GAQVPVVPGIMPIGSSSQLLRFSDACGAEVPRWIRLRLQSYGDDVASIKAFGLDVVTHLC
EQLLAGGAPALHFYTMNQSAATLELCRRLERASPLSA
>A0A7J8QF06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium raimondii|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFDRMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFIKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGI
>A0A7C7V5D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MSSPGSVAELLREAVVVFDGAMGTELYRRHAQPGRSFEELGLSNPDLIRQVHSEYVDAGA
DVLTTNTFAANRATLERFGLAEKLHAIHLAAARLARQAADAADRPVFVAGSIGPLPTQPQ
YDEQREAMIFEQVEALREGGVDLILFETQPNRKALETCAAAMQQLPDVPYALSFAIGEQG
QTVDGEPLSRMLAPLEGLQHQPLFWGMNCGTGPDGLMTALEEAVRLTSVPLVVQPNAGIP
KEIDYRRIYLCSPEYLTVYAKRYVRLGASGVGGCCGTGPEHIQQVAEAVKPLARATRATR
VVVRPAEVEEKTPVPMEKRSRLAWRLAHRKWVTSVELLPPRGYDLTATIDKCTALYRHGV
DATNIPDGPRASCRISPLVTADRIQRQAKIEVILHFCCRDRNLIGMQADLLACAACGIHN
ILFVTGDPPKLGNYPHATGVFDTDSIGMVAVQRRLNCGIDMGGQPIDPPTAALIGVGLDP
TALDQKRELDRFRRKVEAGAEFAITQPVFDPDALLRFLDAVQQFDIPIIAGIWPLASYRN
ALFLQNEVPGVEIPEEVMARMEAAKSREQQLAAGVQIAQESIQRVQDRVAGIQVSAPFGK
IATALAVIEGWGEDR
>A0A7D5MEG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosarchaeum sp. AC2|TrEMBL
MAIIYEINPPKIPDGEISDDEINSSVEKLLQRVSDISNFCDGIHVTDSVLGTKRVSALSI
GRLLKSIHPNLQITISMRVRDKDMNLIKHLTQESIELKLDGILILKGDPSKENPTDSGLI
PSQVVKELNELGYGNKIDFFLSLPSNPNFEKIQKKIAAKPKGFMTQVIHSTEQVQRISNE
LRPKGLRIIPCVLLPSDKNNNSAKFLELDWSNYKENPSNFIKQIHNMSGDVLVTSPNDFT
FAKETLMKI
>A0A2D5Z0C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MLDTPANPSTNTIPGAWSQSTLRDLLLRPEAFVVCVELATSRGTITEQSGRRVLTLARQL
VENPRFDALCVTDNPGGNAMLAADTLGTDLIARGQEVIINLSCKDWNRNALQSRAWALAS
AGFDNILALSGDYPHSGYSGQASGVFDIDSVALLDMLNQMNRGLKITGPSKASNVTMECT
RFLTGAVVNNFKRYEREVMPQYLKLAKKIESGAQFIINQVGYDARKQDELLKYMDRHGLD
APVLANVFVLNARVAKVFHSGRIPGCLVTDALLAQCEKHGAAEDKGKSFFLELAAKQVAI
ARGLGYRGVYFGGHLKYEDYETILDLVESFSPDDWRTFARDVQFSQPDEFFYLEQDPDTA
LAADRVNRQYLASREPNAPRRLRPGPPISYRFSRFLHDEIFARAAPLFNVGKRIFARIDK
SGRFVRRATHRTELALKVLAFDCRDCGDCSLPDVAYLCPESQCAKNQRNGPCGGTHDGQC
EVGEKQCIWALAYDRLKSHGEELDMLNRPVVFKDAALKGTSAWANTFLERDHHARAAEKQ
DPEKPK
>A0A8C3CQI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cairina moschata domestica|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFIK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYISGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A7W8M4L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catenibacillus scindens|TrEMBL
MKGKNMNQIKDFLKRNRLIMDGAMGTYYAQKFARRGEPSEIGNFDAPDAIRAIHMEYIKA
GANLIRTNTFASNYQTLKRSGYGGESHNPGEVVKRNLTWGFNIARDAVNACGRPAFIAAD
IGPVPEYGGRDEQEILDEYLLMAKTFIQLGTDIILFETFSDLKYIVPVAQYIKEHSNIFV
IASFCLNKFGYTKSGISAKKLLKAVEEESAIDASGFNCGIGAAHMYQILKRMDWGTKPIL
VAPNSGYPDTIRDRSVYQENEDYFSEKMAEISRLGVNIIGGCCGTTPEYIRKLAPLVQEP
LEKRPVGKKNADTANVLAESGQGREAEKNPLLDRLEQGGKAIIVELDPPYNGDMEKMIQA
VEILKKYPVDMITLSDSPMGKMRADSIMTGAKVQRELDFPVMPHLTCRDRNQIAMGGAFL
GAHLNGIRNLLIVTGDPVPAGDRTVISSVYDFNSVTLMEYLKQMNEEYFSQDPIVYGGAL
NYGRKNLDKEIERMEKKIRAGASYFLTQPLYSQEDVDRIAYIKSRVHTKIFGGIMPLVSY
RNALFMKNEIYGIHVPDEVIQRYSPDMSREDGEKTGIICALELMEKMQNVVDGYYFMVPF
NRATMIGKIIEQFESETRRK
>A0A1W1YU86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. URIL14HWK12:I5|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>K3VHJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium pseudograminearum (strain CS3096)|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WEAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPSADRP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKAIQDIAQLFVSYLNNKIESLPWSESPLTTEADEIRDDLIE
LNKRGLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPV
ANGAVDTEPIANGTAATTVAN
>A0A3D3W043|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
DAGADAIFTQLFFINDSFLKFRDQCSALGINVPIVPGIMPITDFARIRRITAMCGSVIPA
ELSNRLEAVKEDSAAQFEIGVEYAIRQCQQLQAAGVPGIHFYALNKSDACERILQALNLP
VA
>A0A370F447|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. AG291|TrEMBL
MKVTEHIENANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPSGLLEKKIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIEN
VVALRGDAVKSEIYFKPEKEGNHYASELVTQIADLNKGIYLDADLQNTSATSFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGASYIVTQMFFDNQKFFDFVAKCRKEGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNDAVRQIGIEWCTEQSKELVKAGIPVLH
YYSMGKAENVKAIASAIF
>A0A239TAK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megamonas hypermegale|TrEMBL
MTKIAVELVPRDLAIFEEELKAIKADIPDVDFINIPDLLSCDIRSWDGAGIAKKYFKDAV
PHLRAMDFDFTCELPIKDKLKKYDIKEVLVIEGDPPQTMTHQVYPTISTDIIKKFSDEMP
DIKVYAGIDQYRSSIKEEEYRIRRKMLAGAKGFFTQPFFDMRYLEIYADILDGMDIYWGV
SPVLSQRSVSYWRNKNNVIFPKDFEPTLEWNVAFARKVVEFAKAHNQNVYLMPIKAKIMP
YLEGVLKNNI
>A0A0D2UUH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium raimondii|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFDRMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFIKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQFPHGRWGDSRNPS
YGALTDHQFMRRRARDKKLQEEWATPLKSIDDIQEKFKSFCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGELSDSLSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGATDVNAVTWGVFPAKEIIQPTVVDPASFMVWKD
EAFEIWSRAWAALYPEGDLSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>A0A315CI00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. Jir61|TrEMBL
MNANNSLSIEFFPPKTPEGAEKLRAVRQALYPLKPQFCSVTYGAGGSTQAGTISTLNEIL
SEGMAAASHFSCIGATRDSVRQQLADFKAMGVKRLVALRGDLPSGYGAGGEFQYASDLVA
FIRAETGDDFGIEVAAYPEIHPQAKSAEADLQAFATKVKAGADSAITQYFYNSDAYFRFV
EDADKLGVHIPIVPGIMPISSSSQLLRFSDACGAEIPRWIRLRLQGYGDDIASIKAFGLE
VVTDLCDQLRAGGAPSLHFYSMNQSATTLAICKNLGLAA
>A0A0D2VMP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium raimondii|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFDRMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFIKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQFPHGRWGDSRNPS
YGALTDHQFMRRRARDKKLQEEWATPLKSIDDIQEKFKSFCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGELSDSLSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGATDVNAVTWGVFPAKEIIQPTVVDPASFMVWKD
EAFEIWSRAWAALYPEGDLSKKLLEEVSK
>A0A2S6IDS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineococcus xinjiangensis|TrEMBL
MRPDDSDADRAEARSRSRWRAFAGVLREASYEVLPLPGTDDAVLAHVSREVPLTITTTEA
KGLGPTLELAERLSRAGRTAAPHLVARLVRDGAHLDDIAARLREAGVEGVFVVGGDAREA
VGPYPDALALLEALAERGHRFRHVGVGGYPEGHGTLGAQVMEEALARKAPHATHVITQLC
FDPGATRTWAAETARRGIHLPVRVGLPGAVSRQKLVRISAGLGLGQSARFLLKQQGMFWR
FFLPRGYHPGRLLRGLAPVLGQPGSTLQGAHFFTFNELQRTEAWRRSLIERLERR
>A0A2G4FN62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MRITDLLNTNKVTFSLEFFPPKTEDGERILFEETIPKLKTLNPTFTSVTYGAGGSTRNQT
LRIINRIKKEFNIEAMPHLTCVGSTREMIGEVLEEARGMGVENILALRGDPPKGETEFKA
TEGGFSHSLDLIEYIKVKNQFAIGASGYPEGHIECPDKILDWDRTAAKVKAGAQFLVTQL
FYDVEAFLAFQDYLRTKHKVMVPIIPGVLPFLGAEQVKRFTSMCGAKIPPAILQKIDACK
TDEEVRKVGVEVCTDICSHLIKHGTKAIHIYSLNRVPSSEELVKNLGLI
>B7LA42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli (strain 55989 / EAEC)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEIYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2V6ZIZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MTNPLREALATGQFCYVVELVASALTREARLLEAASGLARISAVVAGSVTSYAGGAMGHD
PLRVAAAARARGLTPNIHLTCVSQDRLGLAKSLDDMHALSLENVFALTGDYPGAGDQPPV
FDLDSVQLVRLIDERRRGGIPFHVAVAVSPFKYTEADCVYQYVKLEKKIAAGADVAVTQV
GWDARKFAELRRYLDDRGLRTPLLGNVYVLGPKTAERMATGRPPGCWVSPELLAAVRAES
RAQDGGRQARLERAARTVAVLRGLGYAGAYIGGTHDAAQIAWIIRRAEELAENWENLAAE
LGYGAAGGFYLPVRKPSMGAGAAPEQRGAELLPRVLEWLGRAFPVNRDTWTRRALTRVFA
WIDRRRPATALLERLELAIKKPLFGCQACGNCVLGHLEYVCPQTCPKQLRNGPCGGTDQG
RCEVIPDKPCIWIAVYDRAKVGNALDGLKVYVPPPDRRLRDTSSWINYFLDRDSRPAAER
P
>A0A7V2IBG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFSRRLAEGPLLFDGAMGTLLYARGVPLDACFDVLNLNNPRLVQGVHADYVAAGADC
LETNTFGANRFKLAVHGLADAVRAVNRQGARLARDVREATGRDVLVLGSIGPLGKYLAPL
GTVTADEARAAFQEQAEGLLEGGVDGFVVETFSDLREIALAIEAIRAVTDLPIVAQMAFT
EDHVTFTGATPAEVARTLRALGVDALGANCSVGSSVLFEVLEQMLAEAGGVPVAIQPNAG
LPSRVGERLMYLSSPAYMAEWAGRMLEAGARAVGGCCGTTPQHIAAMRAVVDRKRPPRPT
VARAAAPRVPAPVEAPGLRTAPPPTVLGRKLAAGEFVVTVELDPPRGHTVDKLVQGAKLL
RERGVEIVDVNDGSLGRVRMAVLPTAILVREATGLDITMHFTCRDRNLMGIQADLLGAHA
LGIRNILAMTGDPPRAGDYVNATAVFDVDAIGLLEIIRRMNEGQDATGQSIGEPTAFCAG
AALDPAPPDPAREIDRLHRKVAAGARWLQTQPVYDLDVLEGFLARAGRVPVPVIVGVLPL
HSHRHAEFLHNEVPGITIPDAVRAEMRRAGEAGVRVGIAMAQRLVTEIRRRWAGVYLMPS
FGRFEVVAEVLDALR
>A0A2V6PPP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MLNQRLREALPGAPGLSTDRMMRTGTSLRDTLSTGVWLCDGAMGTLLYASSGLDSCFDAL
NLSEPALVRSVHAKYIAAGADLIETNTFGANRFKLAPYGVQNHVVQINRSGAVLAREAAD
RSRREVWVLGAMGPLGRNLAPLGSVSPDDARSAFREQATALVETGVDAFVLETFSNLVEI
SLAIEAVRSIADLPIIAQMAFTDERVTFAGRTPGDVAQILRTLPVEVVGANCSVGPTILC
DVLEQMQPVVGALPLSAQPNAGFPRQVGERIVYVASPAYMAQSVARMIQVGARVIGGCCG
TTPEHIAAMRQAIDTASPAHRQPATHFRAPVIGPTPTANPWLQVPRTPLQRKLDRGEFVI
TVELDPPRGHSVEHLVQGAKILRDRGVDLVDINDGSLGRVSMGVLPTAVLIRERTGLDVN
MHFTCRDRNLLGIQADLLGAHALDIRNILALKGDPPRSGDYARATAVFDVGAVGLIEVVR
RLNEGLDAAGNRLGEPTAFSVGAALNPVADDPEREIRLLRRKVSAGAQWLQTQPVYDLEA
LDRFLSRAGGCPVPLIVGVLPLHSARHADFLHNEVPGIRIPEAIRARMRQASERALAVGI
ETAQQLVQEIRRRYAGVYLMPSFGRFDVVAEVLDAFW
>A0A2V7BW23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHEFSRRLEAAPLLCDGAMGTLLYARGVSLDACFDVLNLNNPRVVQSIHADYIAAGADC
IETNTFGANRFKLAVHGMDGRVREINRQGVALARDVRESSGRDVLVLGSIGPLGKYLAPL
GTVTTEEAQAAFLEQAEALLEGGVDAFVVETMSDLDEAALAVTAVRSITDLPIVAQVAFT
DDGATFTGRSAAEVGRFLRMLPIQALGANCSVGSSTLFEVLEQMQPEAGGLPLAIQPNAG
LPSRIGERLIYLSSPAYMAEYADRMVDAGARLVGGCCGTTPQHIAAMRTMLDQKRPGRGG
GVRPTVTVRPAAVSESPGLHVARPPTLLGRKLAAREFVVTVELDPPRGHTVEKLVQGAKL
LKERGVDIVDINDGSLGRVRMAVLPTALLVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALDVRNILAMTGDPPRAGDYANATAVFDVDGVGLIEILRRMNEGLDATGSSIGEPTSFWV
GAALNPAAEDVEREVDRFHRKLQAGARWIQTQPIYDLELLDRFLARAGGSPVPVFVGILP
LHSARHAEFLHNEVPGITIPDLVRRRLRESGDGALRAGIEMSQQLVRDVRTRYAGAYLMP
SFGRFEVVAEVLDVLR
>D0SG33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii SH046|TrEMBL
MMSLLAQYFAQQQFCVLVEYLSAHQTQWSVKTEFAGFPAAMTLADRVHADDDEAPLQVAK
QYPQEIEKVIHFSGKARDIQDFEQFLQDAKTQGQKNLLLLTGDKLKQHHYSHDLEPRTRY
LESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMAA
LQDAHAFLARHQYAQKILACVMPLTLARTKFMLKHEVAGIVITPHMLQVLQQEKEQGLSD
RVYVRCALQILMCRHLGFAGVHLSACHQPEEQSLLESYIEEYRHLSFAECERLWNTLWQV
QTGTEFHPKLVYYSRPATSSQIIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDRSRAK
QALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDREC
IHSVKARLAKAVGQTKILKEKLIPTVSIAVRGTSSWKNWYVEAAS
>A0A2V7HPM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MNHGLDATGNPIGEPTAFCVGAALNPAAAEPQQEMERFLAKAEAGARWAQTQPVYDLELI
ERFFARTRPPIPIVVGILPLHSSRHAEFLHNEVPGITVPEPVRARMRDAGERGLRAGIEM
AQSLLRDVRRRYMGAYLMPSFGRFEVVAEVLDALH
>A0A0Q6MG49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter sp. DSM 101952|TrEMBL
MTPPRPRQTDEHPDGIDLPLDRLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPYDFRPVHLGKKIAAGAQFVQSQYCFDVPMFRTFMQRVRDLGYAEQCF
ILCGVGPLASAKTAKWIRSNVPGIHIPDSIIARLEGAQDQKKEGKQICIDIINEVKEIAG
VAGIHVMAYRQEEYVAEIVDESGVLKGRRPWKREARPDDQLVASRLEHLLHDDVTESQVD
MVKTAH
>A0A2E0MN52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pimelobacter sp. (strain R48)|TrEMBL
MATGHGRSMAELIGDGDRSVSFEFFPPKDEAGAERLWKAINALEPYQPSFVSVTYGAGGS
TRDMTVDITGRIARETSMTPVAHLTCVGHTRQELEKILDSYTEAGVHHLMALRGDPPEGP
RAPWTPTEGGLTYATDLVELARSRGDFRIGVAAFPERHPSSESLDHDADVLAAKARAGAE
YAVTQMFFRAADYFSLVERVRARGVDLPILPGIMPILNLNAIRRQGDLVGTEVPQDIIAR
ISAHTEPEDIRAEGISLAAELCAELLDGGAPGLHFYTLNNSRATLEIFERLQITA
>A0A0F7F8P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus durus ATCC 35681|TrEMBL
MENRLKDKIRNKATGILTYGMTPPKATHPPEKIAEISQKQCERIRDLDIDALILYDVQEE
ADRMEQERPFPYLQTIDPTTYSNVYLSQLSVPKIIYRCVGKYSEAQLADWIKSDTDQDRF
SVFVGSSSSQQKVKLDLTEAYRLSNQHNRNLTFGGVVIPERHMKKNDEHMRVVNKVQSGC
SFFVSQATYDVEASKNFLSDYFYYCTNNGLEMVPILFNIAPCGSPKTLEFMKWLGISIPK
WLENDLKYSSDVLDKSLGLTQKIFAELLEFGLEKGIPVGCSVESVSTRKVEIEASVQLVK
DIKSILDKKLSQAAVI
>A0A2U1JF29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium angustum|TrEMBL
MSLIERINFAISSNIPFFSLEFFPPKTPQGMLNLHDRIGRMKTWNPLFASVTWGAGGSTF
RQSIDFAEMLKRDFDIEPEAKSKGIRTILALRGDEPVNNDYRDILIDNNSESETKPKHEF
RYACDLVEYIRSVPEYSEYFCIGVAGNPEGYCKRFSTEKPETESVLTPEENLSLQEEEEM
KWLLNKVNKGADFILTQVFYDTQKFTTWEQKCRKNGIKIPIIPTILPIQTYSSFIRIVNL
TKIHVPTEINEKLDLVKNDDYKVKSVGVEICINQLDKLVEYGVPGFHFSTLNLELSTYKI
ILESGLLKKGAELAATGKIYPKDKTDISTNNKFQVESVTWDEYPNSRWGDARSPAFFSES
SYGALAIAPRNELNTWGTPTSMRDINELFFRYIKGDIGSLPWTADNISVTDRKSLQILEK
LCLNSIWTLASQSAIDGISSTDPDHGWGPDGGYVYQRSFIEFFVTDSIAEKIFASLQATK
NKYTFYAAKVQQNINCGEDAEPKIISNAVNQDLTNVSVEESSSNDSYNKQQIESTALSWG
VFPGSPVVQSALIDKLNFGFWSKEAINLWSVWANHLAGSNTQRSADFLESIKGSIWLINV
IGNDYKKPNELFDTLEKIVNN
>A0A1Z9JTF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium TMED172|TrEMBL
MKKLKHYASLLETAKLELIPLKNLESQLQFLPPGSTVSVTASPTKTLEDTWELSRRLTEM
GMTPVPHLAARMINGPEHLQSLIDQLPYLGTSELFLVGGDAPKPFGPFQDSIEVLERILE
MDHSITRIGVSSYPDGHAMISNKDLSTALHRKQQLLGESNISGYAATQMCFDPAAVSQWL
SAERENGLTLPIHLGLPGAVDTAKLLKIGARLGIGTSLRFLKKNRGTVLKLLAPGGYNPR
QLLDPLGPKLSRLGIEDLHVFTFNQIESTIAWREKLLNP
>A0A0B6XFF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus bovienii|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPSTTTMEQTLWKSIERLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKDKTGLDAAPHLTCIDANREELRNIAHDYWESGIRHIVALRGD
LPDSSGKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A2U1IWX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium angustum|TrEMBL
MKIIDKINKAEQEGRPYWSFEYFPPKTPQGVLNLYERIERMGKLNPIFIDITWRWGGKSK
NLTQELCINSQTVYGLDANMHMTCTGTNINQVNEALKTSKRNNLQNILALRGDLISNIDT
KLISKDISELTTSDYNEIMMKTNEFQISSQLVKYIRDEFGDYFCISVAGYPEGCTCPNDT
DKDILVLKEKADAGADFVISQLFYDVGKYMQWIDKCKKSGINIPIIPGIMPIQNYNGFTK
MSDLCNISIPDEIWTSLASCKEDDLAVKDFGIKYAIKMIKQLSSYGIKGFHFYTLNLERS
TKLVLEGLQFVSVVAQPDISKELNLTKIQMFNRQEKQLPWPSTQNGKRSGENVRPIFWHN
NASTYIERTNSWDEFPNGRWGNSNSPAFGEIIYGKYWRYSNTKSIELWGLPTTISDIQEL
FVKYCEGELTDLPWSDSPLQLESNEIKDQLTKLNRLGYLTINSQPSCNGVSSTNLVHGWG
PKNGFVYKKAYIEFFIHPEKLQKLIKKLDEYNIENQESPTITYLAVSKHSDNLLTNFGKL
QPNAVTWGVFPGCEIIQPTIVDPNAFIAWKEEAFEYWNLWSKVYSGTYPASHNLIQNIMN
DWYLMNMVDNDYTRSSNFMYDLMSSL
>A0A2V2SN75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MIVRFEILPFGRGEEEAAQLPEDVRLTVTASPTHVLDDTVEVATRLRALGHAVTVHLAAR
MIRDRGHLDALLESMAASGVDDAFVIGGDATPPQGPYGSAMELLALVQDHPQRPSTIGIA
GYPEGHPLIDSSTLAKALEQKSRLADYIATQLCFDPNALFGWVRATRGAGISLPVVVTVP
GMVDRRRLLEISARVGVGPSLRFLRKQGGLRNLLRLSASSADRLYDALVPRLDDPQLNLA
GFHYVTFNRLLKTWRWEREKRRRDVTL
>F4W8I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acromyrmex echinatior|TrEMBL
MCERNDADGNDNPSTPDFHIENPRKTVVDLRQLLKDKISKNEIFCSFEIVSMRKSDAFYR
RLLIGMEEYAPLFYALTWHNKATSDNDGYLPLDLVENFPANTLLHLAAKSLKRDEVIYIL
KKAIAFGIINIFALRGDSLSENGDFEHAADLVVFIRQQFGNTFCVCVAGYPQMHPESPSK
KLDLYYLKAKVEAGADFIITQICFDSRVLINFVRDCREIGIQIPILPGILTPTNHACLEK
MIDICRLDVPIKIKEDLTRMKDDDQAVRKYSVDLIVQIITDVIRNGATYGFHLFTLNR
>A0A835TUR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lamprotornis superbus|TrEMBL
MTRLAAAALKVRRAGSPGSARHQPQPDAVALEQARAACAPCGKRAPGAAETLTMVNETQH
TCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDKWFSLEFF
PPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETI
LHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNHAVDLVKHIRNE
FDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQPETFLKFMKDCQA
IGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSM
CRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRVEDVRPI
FWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEEL
TSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGILTINSQ
PNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKG
QNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPS
RMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLNSPTQHCLRPGSYIQGNYKASI
IEASNGKAGDQTRLSRLNKAFGAQLFPAAVILLASSTAFIVRAVFSVVTGLYPPRALK
>A0A7Z8JWM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas hominis|TrEMBL
MELTMTSHDVPAHLAGAAVPDGLGAVDRPTVSFELFPPRNPDAAPRLWATVQQLASARPD
FVSVTYGASGSTRTTTRQLVRRLLRETSLTPIAHLTCVASSREDLAATVEEFLDEGVRSF
LALRGDAPADRSWEPHPEGLPTASALVELLRDVERRRCASSPAQAVRAATRPLSVAVAAF
PRGNAGAGSTREQDVAALLAKQQAGADFAITQVFYDAGSYLELVALARDAGVTIPILPGI
IPTTDPARLRRVQQLTGVPVPERLLARLDSFDPDDPADLAARHRLGTRLGVDLVNAVLDG
GAPGVHLYTFNAHGPALDLLDGAGLGGDAPRAHLRVPPPEPAAAAPAATTTTPTPVPTI
>A0A672ZKD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaeramia orbicularis|TrEMBL
VADGKHKGLWQSFKSDSSGASTSGGDSSKDSSRCSTPVLEADRSDRLRDKMRRRTESGDR
WFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVN
YCGLESVLHLTCCNQTTHKITGYLEKAKRLGLKNIMALRGDPVGADWEEEEEGFNYAIDL
VKHIRSEFDDYFDICVAGYPTGHPEAGSYEEDLQHLKEKVDAGADFVITQLFFRADTFLK
FLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRNYG
IQQAVQMCRVLLDSGKVSGLHFYTLNREVATMEVLRQLGLWTEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSTKDALL
QMWGDELMNEQSVYEVFTCYITAQPNHRGHKVMCLPWNDEPLAPETNLLKEELEKVNRRG
VLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNY
HIVNVHGQNRTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWGKL
YEEESPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQVIDDMFELLDTPPDPLSDGTASE
>A0A3E2TQL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus catus|TrEMBL
MDIREYLANNRLITDGAMGTWYDRLTGYKGKLAERANLDDLQQIRDIHRAYIEAGARLIR
TNTFAVNSMFFSADEIEAVLKAAWENACQAVSDSGRDVWIAADMGPIDENETKSAADVEN
EYIHLADCFLGLGAKIFVFETLSEFRSVKKAIAYIKAECPDAFIVTQFSFNRNGYTRSGL
SVRALLLEAAAMKELDAVGFNCGVGPLHLYELLKNQSFPEGKYMTVLPNAGYPTELRGRT
FYSENVPYYVDMMGRIAALGFDIIGGCCGTTPEHIRGLHDLLVNDVRPPKKLMPAVYSAD
GKENCAEEAVEEKTDFIQKLERGEKVFVVELDPPFDVNDTKLMEGAALLRDINVDMITLA
DSPLARPRADSIASAIKMRYTRQMEAMPHICCRDKNMIAHRSQLLGMQMNGLRHALIVTG
DPIARGDRESIKSVFNFNSIKLMKYIQTMNQEVFGSRPIYYGGALNHNNGSIDNIAARMC
QKMEAGAQWFLTQPVYGQEDIDRLKELKEKSGGRIIAGIMPLVSRKNALFIKNEMPGIHV
PDQVLERYEAGMSREAYEDVAEAISVDLMKRLEDVCDGYYMMTPFNRAALIKRIILQAKK
ELR
>A0A0H1RZS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pumilus|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSIEEIKR
SFREQLYILLNEEPDGLLLETYYDIEEAKAVLQIARKETTLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPLLENSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHISAMAEAVKGLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKNAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMAKAGEDKEKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKESNIHVNYH
>A0A1Q7N5A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_40CM_3_56_11|TrEMBL
MARNPLRECLQSRRFCHVVEIVASRISREARLLEVASQLATTPGVVAGSITSYAGGAPGQ
DPVRVGTAARARGLTPNIHVTCVSKDRQELRHYLETIAGLGLENVFALTGDYPKDANAVF
DLDSVQLITLMNELRRQGLPFWIAAAVSPFKYTEPDCAYQYLKLEKKFKAGADYAITQLG
FDVRKFRELRRYLDERHIQNPVLGNVYVLGLKSAEKMSKGEPPGCWVAPELVEKIRDEVK
AKDKGEAARLERAARMIAILRGLGYAGAYIGGTHNAEHLRWIIERGQILAPRWKELADEF
TYAPKSAFYMFEPGPAAPRKLRGLSDRAVNALWHLLSPTQIPRGSILEKWARAMFAWIDR
RPTMSHFLERAEFAIKSPAFGCEACGNCVLPDMQYVCPQTCPKQLRNGPCGGTNNGQCEV
IPERSCVWVRVYDRAKHAGEIPLLRIYIPPPDRSLKGTSSWINYFLQRDSRPGSPETSAL
SLRPQATKNPRPTWR
>A0A848KB03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Antrihabitans stalactiti|TrEMBL
MVFDSVRGRSSAGWVSQTPSVVDRLRSETDGRVPFSVEFSPPRDAAAEARLWRAVREFET
MRPAFVSMTYGAGGSTRDRTVRVTGQLAQETTLLPVAHLTAVSHSVEELRAMVGAYADCG
IRNILVLRGDPPGDPLGEWQRHPQGVEYADELVRLVRDLGDFHVGVASFPEGHYRSPDLE
HDTKFLVAKLRAGAEYSITQMFFDIEHYLRLRDRVAAFDAEQGAKPIIPEIMPITSLKSV
RKMVELSGSALPTELEQRLAKAAGDGPDENRAAVREVGIEAASQLGERLIAEGAPGLHFI
TLNFARATSEVLANLGLGAARV
>A0A7W5KAR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. BK069|TrEMBL
MTFSVNQLEEARRALDAPLYADVGGDVDVSFEFSPPKSEKSEETLWQSIETLCPLGPRFL
SVTYGAGGSTRDRTHATVARIARETAVPAAAHLTCVEATREQIDAVAQEYWAAGVRHIVA
LRGDPPAGAADYAPHPGGYENAAALVAGLRRLHPFEISVAAYPECHPSSADLAGDLDNLK
RKLDAGANRAITQFFFEAETFFRYRDAAAAAGIQAEIVPGIMPIGSFAGVQRMAAMCRTD
VPGWLVRLFEGLDDLPAARQLVAATVAAELCRKLYAGGVKQLHFYTMNKAELSYAICHLL
GVRARARETVAAA
>A0A525VNJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. CG24A|TrEMBL
MSREPRRLKEVLDQGQFAVTIEYNPPKGTNISGVLENAKQLVGRVHGVNVTDNTAAVVRA
GSLSVCRLLYELGHDPVMQMTCRDRNRIGIQSDLMGASMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGKDMAGNKLDGSTAYTIGAAVTPEADPLGPMLTKFEVKV
KAGAQFFQTQAIYHPEQFASFMKAVRPFKAKVLAGILVLRNAKMAEFMNANIPGVSVPQD
MIDELRAAGPERAEDVGVDIAVRTIKAVRPHCDGVHIMAIKATHRLAEIITKAEVG
>A0A317N9D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. A11-A|TrEMBL
MSAQEHPLGISFEFFPPNTEAGREKLVGVRDALAARGPRFFSVTYGAGGSTQDRTLTTVR
QVRESGISTAPHLSCIGSEKQQLRELLARYRVEGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSFERDLENFARKMQAGANLAITQYFFNADAYF
HFVERARALGVEAPIVPGIMPITNYAKLARFSDACGAEIPRWIRKQLEAYGDDSASIAAF
GEEVISRLCQRLLDGGAPGLHFYTLNQAEPSLKILDNIVG
>A0A0Q0X2T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas endophytica|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARHLATFNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKANAGANSAITQYFFNADSYLR
FVERVEAAGVTIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A435I4H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.001.04.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A3D5A7S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp|TrEMBL
MTDFQRGNGTSLSFEVFPANTQVGTKKLIQTLNELQDLQPNFISVTCSNNKANIEETTVK
IADYVTNTLRIPTIAHLPAAYLSKQQVSTILGQLEKLGIRHVLALRGDIVEGIPPKRDFS
YASDLVTFIQEQAPYFDISGACYPEIHPDSDNRISDIKHLRKKVEVGCSQLITQLFFDNE
QFYQFKEGCSLAGIDAPILAGIMPIVNRKQALRLIKVSSSQLPKKFLAILEKYEHNPVAL
RDAGLAYAIDQIVDLVTQGVDGIHLYTMNQSDTARQIHQATKSLFQTTELLGV
>A0A2W7TRQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium aquariorum|TrEMBL
MKVTEHIENAKGETLFSFEIIPPQKGKSIQELYDNIDPLMDFNPPFIDVTTSREEYIYVD
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKEGGNNYASDLVSQIYQLNCGKYLHDVMDIDNKADFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLINAVDKCKNNAEIRQVGIEWAIQQSIELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A3S4B4V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermothielavioides terrestris|TrEMBL
MGEFLPSLELPPEAVKNHGMEKITDKIAALPAGTDYFSLEFFPPKTAMGFSNLRGRLDRM
ARALRPLFVNVTWGAGGSTAIKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALDDAK
ALGIRNILALRGDPPRRAEYRDINEPEPTDEEEFAWAVDLVRYIRKTHGDYFCIGVAAYP
EGHADGSHPLGQSLEHDLPYLVEKTQAGADFIMTQLFFDIEAYKHFEKTLREHPSGAFKD
IPIIPGLMPIQSYQMIRRTTKLSHAKIPDALLARLDAVKNDDEKVKEVGVDIISEIVEQI
REIKSRTDAPRGFHFYTLNLEKAVSFIVERTGLISPTTPEPEQAIDDQQNPLPDIGLLRV
NGSATDQSSQEPPRRRQPSIGSDPRDRVIVPGRSASYPDWEATALEASVPAGPINSRANT
LAISEGEGVLGREATWDDFPNGRWGDARSPAYGQIDGYGVSLHVTVAQARELWGTPRTPQ
DVSAIFIRHLRGELSTIPWSEESFSAETDQIRDRLVALNSKGWWTLASQPAVNGLPSSDP
TFGWGPENGFVFQKAFVEFFLPSEDWKALERKLTRPEMKDVVCFYATNAAGDYVSSDTAF
PRAPAAARGGAAAGEQQEASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWGEWA
KIYAKGSDSSRFLESLRADLWLVNIIHHDFVDSEALWELLLD
>A0A399FZ09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division NPL-UPA2 bacterium Unc8|TrEMBL
MSLQSLLEAGKFVVTAEVGPLKGTDTTEIVEVAELLRGRVDAANVTDQQSSVMRMGSLAV
CHLLKESGLEPILQMTCRDRNRLALQSDLLSAYALGIENVLALTGDLPSLGDHPQAKPVF
DLDSVQLLWVIKRLNEGYDMVDNELKGKPNFFPGAVVNPGMGSEAAFELQLIKMEKKIAT
GARFFQTQAVYEPGAFAKFMKRVKGFGIPILVGIIPLKSAGMARYMNKNVAGVFVPEELI
NKMAEAEDKAATGIEIAANLIKELRDICQGVHIMAIGWEKIVPGVLDVAGL
>A0A845RLM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. 4CP|TrEMBL
MKISELFKTGKPTLSFEYFPARTEKNAETLEKTLDVLAGLNPSFVSVTFGAGGSTREGSY
ELVKKLKQEKRLEVVAYLAAYGLRLDEVAAVLDAYQDLGIENILALRGDLGKDGAKEIPT
DTIHYAYELVTFAKKNYNFCIGVAGYPEGHLEAPSLEKDIEYLKYKVDQGADFVIANFFH
DNIYFYHLLERCQKSGITVPVIPGLMPVYSVKMMEMLAANCGATIPEQLKKGIAALPEGD
ADALLEFGTQYAVAQCEELLQEGACGLHFYTMDRSESTAGIVKILREKGLL
>Q7CXU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium fabrum (strain C58 / ATCC 33970)|TrEMBL
MRSETARRDGDIRLSFEFFPPKNAEMDAQLWETVAELKKWDPDFVSVTYGAGGSTKAPTL
DAVRRMIGDSHLPTAAHLTCVDASRDDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYQP
HPEGYENAAALVKGLREIGDFEISVSAYPEKHPESASETVDIDMLKRKADNGATRALTQF
FFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPRFLDERFEGYDE
DLEGRARVAAEVAAEQIADLQRRGFNEFHLYTMNRAPLVDAVLENLGLQRLRRSAA
>A0A7Y2MJ30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. SEMIA 4085|TrEMBL
MALNTGDRRDIGISFEFFPPKSEEMEGQLWKTVAELQDWDPDFVSVTYGAGGTTKAPTLT
AVTRFLNETPLATASHLTCVGATKEETHQVIDHFRKAGVKHFVALRGDAPGGAGVPYQPH
PGGYANAAELVAGLREIGDFEISVSAYPEKHPESRDVAADIDMLKRKADSGADRALTQFF
FDNDNFERYLEKVRAAGVKIPIVPGIMPIQNLTQLKRFASACGTVIPAFLDERFAGLDDK
VEERAKVSVDVAVEQIEDLVRRGLDEFHLYTMNRSPLVSAVLTNLGLRREGAKRAAGAAA
>F7STF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. TD01|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLMHVRDELAARHPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFEIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
HFVEKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GTDVVSRLCERLLDGGAPGLHFYTLNQAAPVLKIVDNLRG
>A0A1A8ZX01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora narathiwatensis|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLASVGVRNVLAVR
GDPPGNPGGEWIRHPEGVGYAEELVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTEHFVR
KCRAGAAFAITRMFFDAEDYLRLRDRVAAAGCDTPILAGVMPVTQMGTIERSVQLSGAPF
PPALAARFEKVADDPEAVRRLGIEQASEMCARLLDEGVPGIHFITLNRSTATREVWQHLR
AEARV
>A0A2Z5JAR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces atratus|TrEMBL
MALGTPSTRTDHARTVREFLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVGPSFVSV
TYGAGGSTRAGTVKATQQIAADSTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDTQHFVD
KCRAGADYAITQMFFNPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLDRFAQLSNASF
PSALKERILAAKDDPAAVRSIGIDFATQFCARLQSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>F7SR27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. TD01|TrEMBL
MINHEKGDDRQVPGPMSYSSAGRLERVLKAGYFAVTSELAPPDSANPEDVYERASVFDGY
VDSMNATDGSGANCHMSSVAMCALLSRVGYDTVMQVSCRDRNRIAIQGDVLGAAALGINN
ILCLTGDGVQVGDHPEAKPVFDLDSMSLLEVIAGLRDKKAFVSGRKISDPPQVFLGAAEN
PFVPPQDFRPYRLAKKIAAGAQFIQTQYCFDLPRFEVFMARSRDLGLLEKCFILPGVGPL
ASARAANWMRDHVPGVHIPDTVIKRLEGAQDQKQEGRQICIELIQKLREIQGVSGVHVMA
HRQESAVADIIEKSGVLRERRPWFPGSDPLLEAPHESPVGLNSG
>X6K6Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L103C119B0|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A7D7LPP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia jinghuaiqii|TrEMBL
MRIAPYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFYPPRDAEAESRLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGQLAAQTTLLPVAHLTAVNHSVAELRALVGAYADQGIT
NILALRGDPPGDPLGEWVAHPDGVEYAEQLVRLIGTLGDFHVGVASFPETHHRSPDIEHD
TRTLVNKLRAGAEYSITQMFFDVEHYLRLRDRVAAADTEQGAKPIIPGIMPVTSLATAQR
MVELSGSVIPPAVEERFARAAGNGPEEDRAAVRAEGIDFATEMAQRLIAEGAPCLHFCSL
NFAKATTEVLGRLGVDVDAALHVPA
>A0A318M575|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella flavalba|TrEMBL
MRRVADRLNNAHRPTFSVEFFPPRDEADEAVLWRAIRELEPLDPAYMSITYGAGGSSRDG
TIRNIARVATDTTLVPMAHLTAVNHSVAELRNVIGHFAAVGVHNILALRGDPPGDPMGEW
VPHPQGLHYAEELVRLIRELGDFCVGVSAFPYGHPRSADLDTDTHYLVRKLRAGADFAIA
QLFFEAEDFLRLRDRVAAAGCDALMLPGIMPLTTPRTLRKTIELSGATPPSWLVDRLAPL
EDDPKAFRAEGLDVVTELCSRLLAEGVPELHFYTFNRSKATRELVERLGLRSPAPPLALT
>G0RA43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypocrea jecorina (strain QM6a)|TrEMBL
MHIRDLVADTEKSGAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLEKVNDALQKAYKAGCTNILALRGDPPRDQTS
WKAADGNFQYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGAGF
IVTQMFYDADNFIRWVGRVRERGITVPILPGIMPIATYASFLRRAKHMQCRIPPDWMAKL
EPVKNDDVAVREIGKTLVADLCRKLLANGIHHLHFYTMNLAQATRMVLDELNWTPSPERP
LKQPLPWKQSKGFGRRDEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKKWGEPKSVQDIATTFVQYLEKKIETLPWSESALSAEADPIKDDLVA
LNKRGLLTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLMPPYLLEEMIRRLDDFP
NLTYYAVTKNGELKSNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGVDW
AHCFDAGTPSRALIEDIMNNWYLVNIVNNDFRENNTIFALLEGLEVKDLAVPASGTTTSA
SGTA
>U4K2R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio nigripulchritudo|TrEMBL
MSYTHASHIDALNQNVAELSDDINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASRDELVNIANDYWNNGIESIVALRGD
IPPGGGAPDMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAINNVKVPGWMSKQFE
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQG
>J7EPI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tobacco|TrEMBL
MKVIEKIQEAAKDENRVVFSFEFFPPKTEDGVENLFERMERMVAHNPSFCDITWGAGGST
ADLTLEISKRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKINGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDVIPANGIATQEIYENDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQLGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPEEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTLGWDEYPHGRWGNAQN
PSYGALTDYQFMRARSRDKKLQEEWAVALNSVDDIYERFKDYCLGKLRSCPWSELDGLQP
ETKIINEKLGHINTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSGEKL
NTLVEKCKAFPYLTYMAINKEGNWISNISQTDVNAVTWGAFPAKEIVQPTVVDPASFMVW
KDEAFEIWSRGWAQLYPETDPSRKLLEQVQNSYYLVSLVDNDYINGDLFSIFKDI
>J7EPI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nicotiana tomentosiformis|TrEMBL
MKVIEKIQEAAKDENRVVFSFEFFPPKTEDGVENLFERMERMVAHNPSFCDITWGAGGST
ADLTLEISKRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKINGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDVIPANGIATQEIYENDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQLGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPEEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTLGWDEYPHGRWGNAQN
PSYGALTDYQFMRARSRDKKLQEEWAVALNSVDDIYERFKDYCLGKLRSCPWSELDGLQP
ETKIINEKLGHINTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSGEKL
NTLVEKCKAFPYLTYMAINKEGNWISNISQTDVNAVTWGAFPAKEIVQPTVVDPASFMVW
KDEAFEIWSRGWAQLYPETDPSRKLLEQVQNSYYLVSLVDNDYINGDLFSIFKDI
>A0A1I4A4S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azotobacter beijerinckii|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLATARQLAGYRPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRSLLNTYKDAGIKRIVALRGDLPSGMGMASGELRHASDL
VEFIRAETGAHFHIEVAAYPEMHPQARSFEDDLAHFAAKMKAGADSAITQYFFNADGYFH
FVERVRKLGVEQPIVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFG
EQVVTDMCKKLLDGGAPGLHFYTLNQAEPSLAIWNNLGLPR
>A0A2H0ATH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG23_combo_of_CG06-09_8_20_14_all_45_10|TrEMBL
MAKHFRETLKTKDFIVTAEAGPGKGSNTEKLVEHIELLKDKVDGLNVTDNQSAVMRYPSL
GTCLLIKEHGGEPILQITCRDRNRLAIQADLLFAYSRGINNVLCLTGDAIDTGDHKEAKP
VFDLDSVQLIHLVHTLNSGKDMAGNELEGGVDFCIGASATPSADPIEPQLMKFQKKLDAG
VGFIQTQAVYDMDELKRFMENFHKMDNIDGVKILAGIVPIWGAKMARYMNENVPGIYVPQ
YLIDEIDQAPKETKAAKGIEMAGRLIRQIKEEKICDGVHIMAIGREERVPAILEAAGI
>A0A415LD89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium ventriosum|TrEMBL
MNIADLFKKEHTVFSFEVFPPKKESGIETIYSTLNELKNLNPDFISVTYGAGGKGVANAT
TIDLCSYIKNELGTETIAHLSCLYNTKESIDRILDELDEKGVKNILALRGDVNPDFAIEK
DFKYASDLTAYIMSKNRGFNISGACYPEVHQEAANMIEDIQNLKKKVDSGADHLISQLFF
DNQVFFDFQEKARIAGINVPIEAGIMPVTNKKQIERMVSMCGASIPAKLSKVLQRFGDNH
EAMRDAGISYAIDQIIELAAHGVDGVHIYTMNDPYVARRISEGVKNILKSGK
>A0A5M7BNB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora hirsuta|TrEMBL
MTANAGLLEQSLNNARFEVLPLKGAVAQAELLPAGTTVTVTASPAKGVEATLDLAARLRE
RDLHVVPHLAARMIGDRSHLTALLDRLDGLGITEVFAVAGDSPEPRGEFPDALALLRAMD
ELGRRPARVGITGYPERHAFIADATTVRAMAEKARYADYVVSQICYDPQTVASWVKAVRA
RGVQLPIFVGVPGVVDAHRLLRISLKIGLGESMRYLRKQHGVVSKLLTRYTPDELLDELS
PHLVDPSAGIAGWHFFTFNEIAKTVQWRHDLVARLREVPA
>A0A841WLE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. 2RC|TrEMBL
MHHTHSPTAFRRAVQAGEFLVTAEVAPPKGGDPTHMIKMAATLKGRVHAVNITDGSRAVL
RMSSLVASLILLQNGVEPICQIACRDRNRIGLQADLMGAHALGIHNILALTGDPVKAGDH
SEAKAVFDLEAVRLLQIIRKMNQGLDCNDKPLTDGALDLFPGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFERLEKFMDTIATGYKKPILAGIFLLKSAKNAHFINKCVPGVN
IPQHIIDRLAKAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIAPILDLAGVATV
NQLVAR
>A0A859TT68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYATDLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A850E3T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tardiphaga robiniae|TrEMBL
MTEINPATPTKLPNISFEFFPPKTEEMDRTLWDTIERLAPLNPSFVSVTYGAGGSTRERT
HATIVRLLKETALTPAAHLTCVGAPKSEIDDVVTRYHEAGVRHIVALRGDPTTGIGTEYI
PHPDGYKTSADLVASIRNRYPDIDVTVSAYPEKHPESADFDADIDTLKAKVDAGATRAIT
QVFFDNDLYFRYLDKVRARGIDIPVLPGIMPMHNFKQARAFVTRAGTTVPDWLAAKFDGL
DNDAETRKLVATTVAAGQVQKLAKQGVSDFHFYTMNRADLVFAISHLLGFRPNGAQKAA
>A0A1Y6K889|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. ORS 285|TrEMBL
MTDLATAITDGHAAIIRPKISFEFFPPKTEEMDRTLWTSIERLAPLEPSFVSVTYGAGGS
TRERTHATIARILKETALLPAAHLTCVGASRGEIDEVVDRYHEVGVRHIVALRGDPPGGI
GTPYQAHAEGYQSSPELVAGIKRRHPDIEVSVSAYPEKHPESRDFDADIDMLKAKVDAGA
TRAITQVFFDNDVYFRYLDRVRARGIDIPIVPGIMPMHNFKQARGFVTRNGTSVPEWLAE
KFDGLDDDPETRKLIAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPKSV
NKVAA
>A0A1F4D5X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_63_13|TrEMBL
MESQKRHPRNFSFEFFPPKTPEGVQRLSATWRQLAQLQPRFFSVTYGAGGSTRDRTLATV
TEIRQAGFHAAPHVSCVGSSRADITETLDLYRAQGIRHIVALRGDMPSGAASMGAFHYAN
ELVEFIREHTGDRFHIDVACYPDFHPQAKSPQDDLRNFKRKIDAGANSAITQYFYNADSY
FRFVDDCEAIGIDIPIVPGVMPINNYTQLARFSDACGADIPRWLRLKLASYHDDIASIRS
FGLDVVTDLCDRLLSAGAPGLHFYTMNMAGPTSTIWQRLGL
>A0A6A5Q0E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae|TrEMBL
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRD
AENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDVKLDLEYLKQKID
AGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQH
FSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANKCLELWSTPTSINDVAFLVINYLNGNLKCLPWSDIPIN
DEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL
>A0A7G4RPQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylella fastidiosa subsp. fastidiosa|TrEMBL
MIPISFEFYPPKNDDQRAQLDRTANRLRAFAPEYVSCTFGAGGSTLSYTSETVRHLSQHH
GFDAAPHLSCVGGSRQEIRELLKLYRAIGCQRIVALRGDLPSGMGHPGDLRYAADLITFI
RAEHGDHFHLEIGAYPETHPQASNTLNDLHYFKAKVDAGADAAITQYFYNPDAYFHFVDA
VQRLGVTIPIVAGVMPISNFDQLRHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVV
TALCERLIAGGAPGLHFYTLNLAKPSTQVLQRLGY
>A0A848FR73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoflavitalea sp. G-6-1-2|TrEMBL
MKVIDHINQAKDTLISFEILPPLKGKTINSIYDHLDPLMEFKPAYINVTYHRSEHVFKKK
ADGTFDKVEVRKRPGTVGICAAIMNHYKVDAVPHLICGGFNKRETEDALIDLNFIGVDNV
LVLRGDAAKNETVFEPETGGNRYALDLLKQVMHLNNGIYLEEDIRDGFRTNFCIGVAGYP
EKHFEAPNLQTDMAYLKAKVDSGAEYVVTQMFFDNQKYFDFVKSCRDAGITIPIIPGLKP
ITTKKQLTVIPRTFNVDIPTEFSNEISKCKSDVEVEQVGTEWMLQQSKELKAAGVPVLHY
YTLGKPKVIYNCVKQIL
>A0A7K8VA34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciccaba nigrolineata|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFVITQLFFRSETFLK
FMKDCQAIGITCPVIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A0M2CU33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria sp. UCD-OTCP|TrEMBL
MTPRPTARPAPPSLSYELYPPRSAASADTLLRTIEELEPTRPDHVSVTYSGDEQRRDSSL
ALLDHLLARTSLRPLAHLTCVGSTRAELEQTVAALVRRGVRGVLALRGDLDPGAEPGELR
HAGELVELVREVEQRHTAALAAGRLAVGVAAYPTRHPESPSFRHDVEVLLAKQRSGADFA
ITQVYFRPQRYERLVAAARAAGVTIPIVPGIMPVTDPRRLRTLCRLAGLAPHPGLAAALE
DAPGPAERHRAGVAFAARLARAALDAGAPGLHLYTFNEHGAALDLLEHVDLPRVPHVPVA
LEDLLLPA
>S3CEG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glarea lozoyensis (strain ATCC 20868 / MF5171)|TrEMBL
MSMPNMDLEKITSKIAALPPGSSYFSLEFFPPKTAMGSSNLRARLDRMSRALRPLFVTVT
WGAGGSTADKSLELAELCQRELGLTTCLHLTCTNMSKELVDRALEDAKALGIRNILALRG
DPPRGEEYDMGKGEGFEWAIDLVKYIRKQYGDYFCIGVAAYPEGHADEGHPEGQSLEHDI
PYLVEKTKAGADFIMTQLFFDVEAYDKFETRLREHESGAFKTIPIIPGMMPIQSYQMIKR
TTKLSHAKLPTNIVDRLDPVRGDDEMVKKVGVDIVSEIVTHIKERPSPCPRGFHFYTLNL
EKAVSFILERTDLIPTSPADDETAILEVPMHHLTVNGSGKHSRRHSSVGSDPHNRVIINE
PKAPLSEFETTASEAGLHAEALNTRANTLAISEGEGSLGREATWDDYPNGRWGDARSPAY
GEIDGYGVSLHMSINQAIKLWSYPKTTDDITSLFIRHLEGTVAALPWSEEGLNEETNTIK
PQLLSLNRKGWWTVASQPAVNGVRSSDPIFGWGPKNGFVFQKAFVELFVPASDWKSLHKK
LTSPEIAPLVSFYASNANGDLVQSYDGEGESTNAVTWGAFPGKEIITPTIIEEVSFRAWA
EEAFGIWDEWGRVYAGKEGEDSRRLIEGFRGDRWLVNVIHHGFVEREGLWEFLLS
>A0A542B3M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. AK1|TrEMBL
MNAFRPSRHGSRRPRVSFEFFPPKTEEMEVALWDSVRRLEPLGPSFVSVTYGAGGSTRER
THATVKRMVDETGLKPAAHLTCVSASKAEVDEVIRSYWDAGVRHVVALRGDPAGGLGTPY
EPHADGYHQTSDLVAGLKRIGDFEVTVSAYPEKHPEAATLDADIDALQKKVDAGATRAIT
QFFFDNDVYFRYLDKVRARGIEIPILPGIVPVQNFKQTANFARKTGASVPQWLADRFEGL
EDDVATRRLVAAAVCAEQVLDLIDRGATDLHFYTMNKADLVYAICHLVGLKPEKPAAQAV
AAE
>A0A3D1P027|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp|TrEMBL
MTPSFDALREARTALDTPLFAGLPGDIGVSFEFFPPATDELREQLWKVVQTLAPLEPRFV
SVTYGAGGSTRDRTHATVSRIIAEAHLPAAAHLTCVDSSRDEIRAVAEAYWQAGVRHIVA
LRGDMGAPGVPFTPHPQGYANAAELVAGLKAIAPFEISVAAYPEAHPDSASAAADIDNLK
RKFDAGASSAITQFFFEPEVFFRFRDRLVAAGIDAPVYPGILPVTNVAQARKFARACGAS
IPGWMDGLFEGLDARPASRQLVAATVCAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPKEAQA
>Q1LS18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)|TrEMBL
MTDRYFSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSTRDSIRQILQTYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQARSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVD
DVRAMGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDKEAIRAFGLDV
VTDLCTRLLEAGVPGLHFYTLNAAGATKAIWQRLKL
>J7T7Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius K12|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFKYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDSESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHEATHSLFKHHSQVSAL
>A0A5N6HSZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus pseudonomiae|TrEMBL
MHIKEKLGQNEAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREQQK
WEAAEGGLRYAKDLVRYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFIDWVKKCRAKGINVPIIPGIMPIQTYSAFIRRATWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIRDLSHLFVSYLEGKLGRLPWSDTPISSEAKTIKPNLIE
LNNRGILTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELITRIESNE
DLTYHAVSKNGELRTNTQDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDNWYLVNIVNNDFHNTYDLFELFKDLNVKDFDVEVTADNADSK
SQEAEATAN
>A0A7Y6Z551|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium|TrEMBL
MKLMKQSGQQPGLDETAAVVRKLARTASVEVSPDRILGSQTPKVAELLPAGTAVYLPCLP
QTRFEDILAACQQLLAADLQPVPHLAARRLKNRAELQQRLSRLYETGTRQLMLIAGDVDQ
PAGPFRDTLDLLQCGLLADQGFHRLGIAGHPNGHPKVNEKALTHALETKREYARSTGARL
WVVTQFAFEATRYTDWVARFDDSTLPLPVYCGLPGPTRIRTLLAYAAHCGVGVSARLLRR
TPGAARLLRAWTPDGVVEALAQHCRAHPSTHLAGIHLFTFGGLETTAQWLHRLRDDPQQQ
SSQVST
>A0A7W4BTH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. SG44-2|TrEMBL
MAFHHAQHAQSLNQSLSELNDINVSFEFFPPSTPAMEEILWNSIRRLEPLNPKFVSVTYG
ANSGVRDRTHSVIERIQKETNLLAAPHLTLVDASDEELVELAKHYWNSGIRDIVALRGDL
PDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDARNAQADLINLKKKIDAGANRAI
TQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVTNFKQTKRFAGMTNVAIPHWLHRQFEG
LDDDPATRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A5I0CXR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Ouagadougou|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A832QVK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus solventivorans|TrEMBL
MTAPRISFEFFPPKNLDQSFKLWETANALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
NYGLNVAAHLTCVEATRAETMQIVDDYAAAGVREIVALRGDPPQGADRFRPHPEGFADSV
ELIGAIAARGGFKIRCGAYPEPHPESPDTAADVAWLKRKIDAGASSAITQFFFDADVYFR
FRDACDAAGITAPILPGILPVQSWAGAKRFAARCGASVPQWADEAFAAAGPEGERALAID
MAAGLCRRLIEGGVERLHFYTVNRPDMTLAVCKALGIEARQAQVA
>A0A7X9NGC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalicoccus pleomorphus|TrEMBL
MKVSEILTQDKVTLSFEVFPPKKIDDYSKVEAAAKKIASLHPDFMSITYGAGGGTSQYTV
DLARDLYQKYGTQVIAHLTCVSSTREHVLDMIQKCKDASIENIMALRGDIPKDGRIAHDY
QYASQLIQDIKAQGDFCIGGACYPEGHIECEHKKEDILHLKEKVDAGCDFLTTQMFFDNN
IFYNFLYRIREAGIQVPVLAGIMPITNKKQLARSVQMSGTQVPERFKAIIDHFGDDPKAM
EQAGIVYASEQIIDLIANGIRHIHVYSMNKPDVAARIQANLSEMIK
>A0A7C2KID8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MTLKEKLNSDKFIVTSEIGPPKGINTAKSLEDAELIRNRVDAINVTDLQSAVMRLGSMVT
CYLLKQRGIDSIYQISCRDRNRLALQSDLLSAAVLGIENVLIITGDHPKCGDHPEAMPVF
DLDSVHLIEAAKQLQSGKDLSGKELDGTPSFCIGAAVNPTAEPVEPEIIKMEKKAAAGAE
FFQTQAVFDAEKFKEFLNLTKHINVPVLAGIVLLKSAAMGRFMNKNIPGVCVPDKFIEQM
DKASDKQEKSIEIAARTIDEIKGLCRGVHIMPIGWAKVVLPLLDAARL
>A0A1B1BS35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio crassostreae 9CS106|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A3C0MYC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MMFKEKLASGRPIITSEIGPPKGISLDKILAEIAPIKGRVDAVNVTDLQSSVMRMGSLAA
SVILKNHGFEPILQMTCRDRNRLALQSDALSASALGIENILALTGDHPSLGDHPGAKPVF
DLDSVQLVDILRVLQTGVDAGGNKLVGTAPKYCLGAVVNPGADPLEPEIIKMEKKLEAGA
EFFQTQAVFDIRVFETFLKSCSYLNAKVLAGVVLLKSERMAQYMNDNVPGVTVPEDIIKE
MAGAQDKKVKSIEISVRLIKELKGMCGGIHIMPIGWYSIVPPILDAI
>A0A2E2G197|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium|TrEMBL
MTTLSFEFFPTKTEEGTEKLLKVRDELAAFNPEFFSVTYGAGGSTRDRTYAIVKAIQERG
IAAAPHLSCVGDSKDDLRSLLNEYKDLGIDRIVTLRGDLPSGAGLASSELRYANELVEFI
REETGDHFTLEVAAYPEMHPQATSFEKDLEHFVNKVKAGADSAITQYFFNADSYFNFVDR
VRDMGVDIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDNNESIQQFGEEVV
TEMCHRLLEGGAPGIHFYTLNQSEASLRVWRNLV
>A0A2N6F5U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MSRLQEAMAGGRFVATAEVAPPKGVAVAEALATAAAFDGIAAVNVTDNQGANMRMTPLVL
AGKLAEAGVEPILQLTCRDRNRMALQSDLLGAAALGIENLLLLSGDHTRFGDHPEARSVF
DLDSVQLLQVVHSLAQGCDMSGTELAGLPAFFPGAAVNPESEPFELMFQKYRKKIEAGAR
FFQTQAVFDSQKLEHFMDDAGPLNVPVLAGVLLLKNSRMARFLNANIPGVKVPAAIIERL
DKASDPLAEGVAIAREMVSVARDRCHGVHLMTLGLEAKIPEILRQN
>A0A0Q0B3N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. savastanoi|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>A0A419RR25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantiacibacter aquimixticola|TrEMBL
MSLAQPIPEFLDPASEQDRAHKRPLFSGLPGDIAVSFEFFPPKSEKMESQLWESVTKLAP
LSPQFVSVTYGAGGSTRERTHNTVARLIAEAGIPAAAHLTCVDASRAETQRIAEAYWEAG
VRHIVALRGDAGEPGAPFVPHEDGYGSAAELVAGLKEVADFEVSVAAYPEVHPDANCPQS
DLENLKRKIDAGATRAISQFFFSAETFFDFTERCARAGIEAPVVPGILPVTNVAQARKFA
GQCGAVIPDWMDGLFEGLDDFPGARQLVAATVAAELCRRLYAGGVREFHFYTLNRAELAY
AICHMLGKRPQEQAA
>A0A2P8WKN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|filamentous cyanobacterium CCP5|TrEMBL
MTGSSANQSATRGYTFRQAVKDEAFLVTAEVMPPKGGNPAHMLKMAKYLRHRVHAVNITD
GSRAVLRMSSLAAATLIQQAGIEAICQMACRDRNCIALQADLMGAHALGLGNVLALTGDP
VKAGDHPQAKSVFDLESVRLLKLIRQLNQGTDSNGKPLPDEPLDLFAGAAVDPQLPSWSG
LQRRFEHKLDAGAEFFQSQMITDFERLASFMHKVASQSDKPILAGIFLLKSAKNAAFINR
CVPGAQIPQSTIDRLAQAQDPLQEGIQIAAEQVQMARQLCQGVHMMAVRRENLIPQILDR
AGVLPINAVSPSISRSPAGTLSGQT
>A0A4Y3KI99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas gelida|TrEMBL
MSERSVRVSAATAVPPVAAPRPSDALAAPGATTTTETRAVTGTHVAPSPRPLGSVDRPTI
SFELFPPRNPQAAPRLWETVRALESVHPDFVSVTYGASGKTRETSRALVSRLLQETSLSP
IAHLTCVGTSREEITTIVEEFLDEGVRSFLALRGDPPVGQDDWQAHPDGLATASELVGLL
REIESRRCTASPAQAVRARVRPLSVAVAAFPRGNAATGGTRAQDVASLLAKQEAGADFAI
TQVFYDAEAYLGLVAEAREAGVVIPIIPGIIPATDPARLERVQALTGVPVPRALLETLAS
ADDERERHRRGIRAGVDLINGILDGGAPGVHLYTFNTHGAALDLLEGADLDGRGRD
>E7A4G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae F3031|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A358AGC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MTFKEKIQAGKFILTSEVGPPKGIESGRILEDVELVRGRVDAINVTDLQSSVMRLGSLAV
SIRLKEKGFEPVYQVTCRDRNRLALQSDILSAANFGIENILALTGDHPKLGDHPHAKAVF
DIDSVQLIQVIRRLEQGLDMAGKKLEGVLPKFCVGAVVNPGSDPLEPQIMKMEKKIDAGA
EFFQTQAVYDLKSFENFLSKTKHLKTTVIAGIVLLKSAGMAKYMNENVAGISVPDNLINE
MRDTKDKQAQSIEIAARLIKELKPMCQGIHIMPIGWDKLVPKVLDAAGL
>A0A3A4JW76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MSLKERIVQGEFVITAEIGPPKGKEVAQVLKTAEELMPYIDAVNVTDLQSAVMRLGSLAM
CIFLRQRGIEPIMQVACRDRNRLALQSDILSAAAHNIPNILILTGDHPVLGDHPDAKPVF
DLDSVQLLEVVKKLEEGFDMRGNKLEGEPPHFYKGAVVNPGARPLEPQILKMEKKIEAGA
EFFQTQGIYDIKIFEHFIHKTSHLKVPVLAGIIPLKSDTMARYINKNLAGVSVPDVLIRQ
MQEAQNKAEKSIEITSSLIKGLKGMCQGIHLMALGWERFIPDILASAQINRK
>A0A4P8A1D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium tyrobutyricum|TrEMBL
MLKDKILNRETGIITYAITPPKLNNLHQKIVEISQKQVERIKNIDVDGLIIYDIQDEIDR
QKEKRPFPFIETLDPALYNEEYLKNLTVPKIIYRCVGKYDENQFSKWIKSDKDSDRFSVF
VGASSSKQEVKLKLSEAYRISEQLNPNLILGGVVIPERHVTHKDEHMRIINKVGKGCKFF
VSQVIYNLENSKNFLSDYYYYCKNNNIEMKPIIFTITPCGSKKTLQFMKWLGINVPKWME
NDLMNSQDILHKSVSLSENIVEELLDFALEKDIPVGFNIESLSIRKVEIEASIKLVKDIK
SIIEKRLK
>K7FMS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelodiscus sinensis|TrEMBL
MVTEPPCVSNGSASSRSDGGSSSGSESSKDSSRCSTPILDAERHERLREKMRRRHDSGDK
WFSLEFFPPRTANGAVNLISRFDRMGMGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKEEITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVDL
VKHIRCEFDDYFDICVAGYPKGHPEAESYEADLRHLREKVSAGADFIITQLFFRSETFLT
FMKDCQAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKEVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVPGLHFYTLNREVATTEILKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYISGEPNREGHKVTCLPWNDDPLAAETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSENITALLKVLKMKKYELRV
NYHIVNVRGENIANSPDLQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVMEDTFELLNCPTEQQLNYRGG
EEP
>A0A6A0AQ09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CWH03|TrEMBL
MALGTASTRTDRARTVRDMLATGKTSHSFEFWAPKTEKGERNLWNALRRIEAVRPSFVSV
TYGAGGSTRAGTVKATQQIAADTTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPDGVRYAAELVRLIKESGDFCVGVAAFPETHPRSSDREADIRHFVD
KCRAGADYAITQMFFHVEDYLRLRDSVAEAGCETPIIPEIMPVTSVKQIERFAQLSNASF
PAALEARIRAVADAPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQQS
>A0A5P2EUX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium diolis|TrEMBL
MIKEILKNDILICDGAMGTYYSEVTGNDVSYCEFGNLNDKETIKRIHKEYIEAGAKLIRT
NTFSANTYDLGVSLETLMDIIKSGINLAKEVTRNTSVLIGASIGPIKTDNLDEFSNEVLE
EYKYIVDCFLKNGIDIFIFETFSNYNYLKKISEYIKYKNIDSFILTQFAVKPDGFTRDGI
SAAKLIKEVRNTEYIDAFGFNCGSGPAHILEMVKKINIENEIVSVLPNAGYPEIIHERTV
YPNNPVYFAEKVSEIRSFGVSIIGGCCGTNPSYIKQLTKIINENSKVINANTKAEPKVKS
FEKKAKNTFKDKLENGEFVVAIELSAPIDTDISRIIDGAKICKENNIDLVTVPDSPMSKV
RADSTIISSKIKREIGIEAMPHVCCRDKNTNAIRSSLIGSHIENIRNILAITGDPISDAS
KVETKSVFNLNSFRLIELIESMNEEIFKEDSIYVGGALNLNVLNKEVEYNRMMKKIEKGA
KFFLTQPIYDDNAIEFLKMIKERTNVKILAGLLPVVSYRNAMFLNNELPGVTIPDKYVQM
FSENMSKEEAQEIGVKITVEIGKKLKGIADGLYFITPFNRVNMLIEIIKQINA
>A0A1F3X8F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionales bacterium RIFOXYD1_FULL_44_7|TrEMBL
MEQIRNLNKGSYLPRRNDPGSQNQEPTSFCIGGAAYPDMADEHQRISYFKRKVEAGAEYG
ITDMLFDPESYARFLDSCGKNNINVPILPGTRILKSQDQVQKMLARFKVNVPKKLIDSLP
EKDGPDCFERSIDLFVEFAERLNVLGAPGIHVFVIGDTSGACEALRRLAEGPKKVRYVVE
GS
>A0A2H0AUK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG23_combo_of_CG06-09_8_20_14_all_51_20|TrEMBL
MSDYKAGSNLEKVLKAGKFAFTGECGPPQGANITKLKEKAAHLKGCVDAVNITDNQTAVV
RMSSWAASLTVLQEGVEPNFQMVCRDRNRLAAQSDVLGVYSHGIRNMLCLSGDHQKFGNH
PEAKNVFDIDSIQLINVVKTMRDEGKFMNGQEIDVPPKLFIGAASNPFAEPYEFRVFRLA
KKIAAGADFIQTQCIYNMVRFRDFMKRVVDMGLHEKCYILAGVTPMKSVGMAQYMAKQVP
GMDVPDSLIKRLKGAPKGKAAAEGIKMAVEQIQEFKEMPGVAGVHLMAIEWEHRVREIAE
LAGMLPRPVV
>A0A2H0AI50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG23_combo_of_CG06-09_8_20_14_all_51_20|TrEMBL
MNQTRAVKTDSKLEKILAAGHLAVTSECGPPRGSDSDLIKKKAELIKNHVDAINITDNQT
SVTRLCSLASCIHLKLMGLEPVLQMVVRDRNRIAIQSDVLGAASFDIRNMLCLSGDHQRF
GDSSQGQNVFDLDSMQLIQTVRRMRDEGKFLGGDEIKRPPKLFVGAAANPFADPFEIRVR
RLAKKAAAGAEFIQTQCIYNLDRFEEWMKQVRDRGLHEKVYILAGLTPLKSAGMAKYMKN
RVPGMDVPDDVVKRMSGVPKEKQPEEGIKICVESVQRLKELEGVAGFHIMAIEWEEKVPE
IVEMGGLYPRPNPDAI
>A0A6J4JM64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Acetobacteraceae bacterium|TrEMBL
GPVLSRHAATLADRAPSRRPAGAGGDARAPALLRVLPAQDGGAGGPALGLRAPLGAVAAA
VRVRDLRRGRQHPGAHPRHRVAHPARDDPHAGRAPHLRGRLARRGGPGGAGLLGRRRAAH
RRAAGRPAAGRGALRAASRGLCLRGRPGGGPAPHRALRDQRRRLPGGAPDRPFGRPRHRQ
LEAEDRRGRHPRHHAVLLRHRCVPALPGSLRGGGHHRADRPGHLPGEQHRPGEEVQRHVR
RQRPWLDGPPVRRAG
>E4ZDV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria lactamica (strain 020-06)|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>N9U2K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas diversa CDC 2478-85|TrEMBL
MGFHSARQVEALNQSIADLGGDISVSFEFFPPNSESMEQTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGVDKPDMYAADLVALLKAEADFDISVAAYPEVHPEARSAQSDLLSLKRKIDAGADRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLTKFAGFTNVKIPRWMHQRFE
GLDNDQATRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKVA
>A0A3M5PGA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas marginalis pv. marginalis|TrEMBL
MTMSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQ
LESEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIQRIVALRGDLPSGMGMASGELRYAN
DLVSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSY
FYFVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQA
FGEQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1I0QYH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] fimetarium|TrEMBL
MLNIREYLKNNRLIMDGAMGTYYSDLEGDESAFSEFGNINRPEIIEKIHSDYINAGAKLI
RTNSFATSIEALGVTVFEQKRIIEASCEIAKRAAKDKAYVAGDIGPIKENAESTESEILD
EYIRMCDIFLAADVDVILFETFSDMIYIKQLVKYIRSKKDVFIMTNFCLNKNGFTRNGLS
ATKILSELAQIDEIDACGFNCGIGSGHMSNIMKKLKYPSNKYIACIPNAGYPEQMQNRMI
FMDNVDYFSNNMKAIADLGIDIVGGCCGTRPTYIKKLAEKIDLKPVKKVSFLGSDIAEVH
KELRKNVFYSKFETGKKVIAVELDPPFDADYEKLVEYAHTLKKQGVDIITMADSPMGRSR
VDSILMSVKLANETGINVMPHICCRDKNMIAIRSTLLGAYINDIRDLLLVTGDPVPSESR
RLTTGVFDYNSIQLMNFVKEMNQEHFADEPFYYGGALNPTMGKIDNIIDRIQKKIDAGCK
YFLTQPVYSDDAIERLAEIKRRVDTKILCGIMPLVSYRNANFMKNEFIGIDIPDNIVARY
RPEMSKEEGEETGAKIARELMEKLNPIVDGYYFMLPFNRVSLIGKILG
>A0A6C1YSG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris|TrEMBL
MSPDPPSPAATITDAYSLEVGALDMPALTAAAPQIMRGSSMFIPYLPSQNDEVRLAAAQR
VRALGFAPMPHLSARRIASLDALQAFVRRAVEDAGVERCLVIAGDAPSAVGPFSDSESLI
ETGVFEHLGIKTIGVAGHPEGHPSMPASAQWDVLERKCRSIAERGMAPLIVTQFAFDADT
VLTWLDALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACASMLSKYGISLGKLFGTA
GPDRFVDRLTAGLGEARGDVSLHFYPFGGIAQSVAWVEQYRHRSARPLAD
>M5PHA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sonorensis L12|TrEMBL
MSFLEDIKRKTLIADGAMGTLLYSYGIDRCFEELNISKPDEVKRIHEAYVQAGADIIQTN
TYGANYIKLSRYGLEDETKQINEKAVRLARSAAGSAYVLGTLGGIRTFNKNAYSLDDIKR
SFREQLYLLLNEQPDGLLLETYYDLEEAREVLKIARKETELPIIVNVSMHEEGVLQDGTP
LSEGLKLLAGLGADVVGINCRLGPYHMITALEEVPLLEDAYLSVYPNSSLPSLVEGRLVY
ETDDEYFRNSAIEFRNQGARIIGGCCGTTPNHIRAMAEAVKDLPPVTEKQVKIRKKAAAA
VQNARTEPALNELAKEKRSIIVELDPPKQLNFEKFIRAAKELQSAGIDALTLADNSLATP
RISNVACGALLKQRLDMRSLIHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRIE
KKIACGADYFISQPVYSEEQLIKIREETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDAIREKMALAGDDKQKQAEEGLAIARSLLDAACDLFNGIYLITPFLRSDLTAELTAYIH
QKEKETTNVYHQ
>A0A1F4ELW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_67_28|TrEMBL
MYAARRWSVRHARGLRSVYQTLARLAPWLAPLVRLLGRAGAEAVARPVERAIKGFLFDCR
MCGECVLSGTGMACPMNCAKQMRNGPCGGVRADGGCEVDPQVRCVWLEAMDGAKRIGLSV
KEGGALLRPLDHAREGRSSWVPVILSEPPRAEPPRGGAPITHEPGPLERACQSGRFVVTV
ELAPPDSADPAGFLARADHFENLVDAINLTDGAGGNCHMSSVAASAILAANGHTPIYQVV
CRDRNRIAIQGDILGAAALGVRNILCLTGDDVSQGDQPQAKPVFDLDATTLLGIARGMRD
AGTFASGRRLEHAPDFFLGATVNPFVPPHAGRIANLENKVAAGARFIQTQFCFDVGRMEA
FMRAVRERGLHRRCTILAGVGTLGNAKALQRMAEKVPGVHVPRELLERIGRAADPRAESK
RAAIGIIRALSQIEGVGGFHFMGHRNESTLAEIIVESGLRRCGRAPAAATGG
>A0A6P3BZV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MSSLKQALNAGRFVCVLEVVPQQSPSRLAALGQILQRGHLAGWPLLPSFADRVGLHSDLS
PLEGAGALGNPASSLLHFSGKDRERADLLRQIESMKARGLEQLLLLSGDRLPGHHPDQAP
VRYLESVPALQIAREHCPDWLLGAALNPFKYREEEGGAQYLKAQKKLLAGADFLTLQLGF
DAAKHGEAQAWMRAQGRTKPMLACVMRLTGKRAAILQAVPGVVITESMRALLDNEQQVSQ
AYAGARSLERLALQIVGLQLMGYAGVHVSGVHTLDELVALEQAITGLRDSVTSLADWSER
WHASWQMPGAPLVCFAPEIDAWEMGQSDVTATRREHLRYTLLSAVHGQLFNRTGWLSRAF
GWSVTRPIWKVDAAANALHAVERTVKRPLVGCDTCGRCRLQDTLYVCPETCPKGLANGPC
GGTRLNRCEFGDRECVHSVKYRIAKSANQFAVLGQTLIPCIEAGDRHRSSWPDWFEPDDP
TSGR
>A0A7L9S7N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassotalea sp. LPB0316|TrEMBL
MNNGSELKARYNDNNRGVYFIGTTPPKSDTPVDQVDTIAQKLLERVSDIDVDGFIVYDIQ
DEGSRTNAPRPFPFKSTHDPRLYASLLNQKSTRPVITYKSVGQSSVEDIQQWADEAWRDY
NVRDLVLVGSPSHKNRVSLSLEDAYKAVKESSHEFFTGGVTIAERHASKGNEHQRLIEKY
QQGCNFFISQAIYNPQATIDQLTRYAIECKNLGLKPQRIILTFSPCGSEKTLAFIEWLGV
SVPEATSLRILNADKPLYESIRICSNSLQQILDAVIPYNLPLGLNIESLTNRKEEIDGSI
LLYKLLRSMMDNYLAKNELLTLSRS
>E6U1U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Evansella cellulosilytica (strain ATCC 21833 / DSM 2522 / FERM P-1141 / JCM 9156 / N-4)|TrEMBL
MGLLDDLKKQVIVADGAMGTLLYSYGVGNCFEEMNLSHPDQIKEIHGAYLAAGSQVIQTN
TYGANYEKLLRYGLEDQVKNINTKAVRLAKAALEEHRSDLSSFSSEENKYILGTLGGVRA
VPGKPISLTEIKRSFREQLYCLLMEEVDGILLETYYDFEELKTVLQIARKETQLPIIAQV
SLHDIGIVQGGISVDDAMKTLDDLGANIVGLNCRMGPHHMIRSLEQVSIPENAYLSAYPN
ASLPSYSNGRYHYSSNSEYFQQSANLLWEQGVSLIGGCCGTTPEHIKAIADAVKGKAPIT
EKEITVNQKSVVHIETPEPPKVEKLNEVVKTRSSIIVELDTPKDLVTTKFLEGAKALKEA
GVDAVTLADNSLANPRICNLSMSTILKEKLQVTPLAHITCRDRNLIGLQSHLMGLSTLGI
DNVLAITGDPAKVGDFPGATSVYDLSSFELIQMIKQCNEGLSFTGKPLGKKTNFTVAAAF
NPNVRHLDKAVERLQKKIDCGADYFMTQPVYSEKQIENIYEHTKHIKAPIYLGIMPLTSY
RNAEFLHHEVPGIKLTDDIRQAMALHKEDKARSQQEGIAIAKNLIDTALHYFNGIYLITP
FTKYEITVELTNYIKEKTSAATDRQAGPIRKVYDGNII
>A0A6L5BLL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas frederiksbergensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A7W6L6Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris|TrEMBL
MSARRSCDAARFHCAPWHCFHSIRADGAAPPNHPHRTTRPLIHPETPSLASTITDAYSLE
VSAKDIAGLAAAAPGIMRGATIAIPYLPNQDDDARLAAARMVRKLGFEPMPHLSARRIAS
LDALHAFVRRAVDEAGVARCLVIAGDPASPAGPFSDSLSLIATGVFERSGIQTIAVAGHP
EGHPIVHATDRWDVLERKCRSIAERGMAPLIVTQFAFDADIVLTWLSALRAHGIQHPVRV
GVPGPAGVAVLARYAARCGVGACASMLSTYGISLGKLFGTAGPDRFVDRLATGLTEAHGD
VRLHFYPFGGIAQTVAWVERYRSRIARPGVD
>R9K4H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium M18-1|TrEMBL
MKIIDRLNEDKIHISFEVFPPKTDAGFDKVLDATDKIAALKPSYISVTYGAGGGTSKNTA
RIASHIKEDLGVLSLAHLTCASSTKEEVRSVIANLKQLGIENILALRGDIPEGMIFPSED
RFRYAWELVEEIRKHGDFCIGAACYPEGHVENEHKADDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSATQMKRSQELSGTVFPRRFLALLDRFGGHPE
AMMQAGIAYATDQIIDLLSNGVKNIHIYSMNKPDVAAKIMSNLSEIIRC
>A0A2S6VIC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroococcidiopsis sp. TS-821|TrEMBL
MLNNLNGTSLNSLRTAIIQGDFLVTAEVAPPKGSNPAHMVQMAQQLKSRVHAVNITDGSR
AVLRMSSLAASVILLQHGIEPICQIACRDRNRIGLQADLMGAYALGIRNILALTGDPVKA
GDHVDAKSVFDLESIRLLKLIHKMNSGTDCCDQPLTDGATDLFPGAAVDPQLASWSGLQS
RFERKLEAGAQFFQSQLITDFDRLEKFMDQIAKGCGKPIMAGIFLLKSAKNAQFINRCVP
GVNIPQHIIDRLEQAKDPLQEGVKIAAEQVQIARELCQGVHMMAVKREDLIPQILDLAGV
APVKKEPVLSMTTQVK
>A0A3M4RTG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. glycinea|TrEMBL
MEVPSTMSQDRSFSFEFFPTKTEAGHEKLLNVARQIASYNPAFFSCTYGAGGSTRDGTIN
TVMQLQNEVKVPSAPHLSCVGDSKDDLRVLLNQYKEAGIKRIVALRGDLPSGMGMSSGEL
RYASDLVSFIREETGSHFHIEVAAYPEMHPQARNFDDDVKNFVHKAQAGADSAITQYFFN
ADSYFHFLERVQKKGVTLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQ
SIQAFGEQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A4R2N5Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Simplicispira metamorpha|TrEMBL
MTTSSATSTTPATHDSVAPGVPYPISVEFFPAKTPEGADKLRAVRQQLYALGPQFCSVTY
GAGGSTQEGTFAAVRDILAEGQSAASHFSCIGATRDSVRAELAQLQAMGVQRLVALRGDL
PSGYGVGGEFQYASDLVAFIRAETGSSFHIEVAAYPEVHPQARSPEADLQAFATKVRAGA
DSAITQYFFNADAYFRFVDDAQRLGLQVPIVPGIMPILGATQLMRFSDACGAEIPRWLRL
RLQGFGDDTASIRAFGLDVITTLCEQLRRGGAPALHFYTMNQSAATLEICRRLGLRD
>A0A556RCC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium asteroides|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLMPDFISVTYGTGRRSDRTATARIAKTIH
TEYGIPAVAHLTAQYADREVIDQALDMFDDAGVAAVLALRGDSVEGREPAGVFEHASDLA
AYIRSRRPNLSIYGACYPETHPEAASPEEDMENLRIKVDSGVDHLVSQLFYDNADFLDFL
DRARAAGIRVPIEAGIMPITNEGQVRHMSEVCKARIPAAVESILDRWGDDRANLREAGII
YASQQIADLVAHGVDGIHLYSMNHSGVTRRIWHNVRHLFRQVGTKEEPVSNQK
>A0A5C8ACI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVTEHLKEAKDTLFSFEILPPLKGKSIQSIYDGIDPLMEFKPRFVNVTYHREEFIYKER
ENGLLEKIAIRKRPGTVGICAAIMNKYQVDAVPHLICGGFSKEETENALIDLQFLGIDNV
LALRGDSIKTEATFRPHKDGHKYAVELIHQIGEMNHGNYMMDDIQLEPTDFCIGTAGYPE
KHFEAMNMTTDLHYLKAKVDAGADYIVTQMFFDNQKYFDFVAACREIGINVPIIPGLKPI
KTLDHITFLPKFFKIDYPEALSKELLKCKDNKQVEQLGIEWGIQQSKELKEANVPCIHYY
TMSNSSMVKAIAKEIF
>A0A3M6HYU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. tabaci|TrEMBL
APTKYVFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAG
GSTRDRTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPS
GMGMASGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGAD
SAITQYFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQ
LEAYGDDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A436LDU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.001.01.1.1|TrEMBL
PEDVYNRAKIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAI
QGDVLGGAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRK
LTTPPQLFLGAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLG
YTEKCFILVGVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINE
VKEISGVSGVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDI
TETQVDMVKTAH
>A0A0A2H1M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dokdonia donghaensis DSW-1|TrEMBL
MTKVRDHIAEAIAAKRTDFSFEILPPLKGQNINTIFDNIDPLMEFKPPFIDVTYHREEYI
YKEREDGLLEKKVVRKRPGTVGICAAIQNRYQVDAVPHVLCGGFSKEDTENFLIDMDFLG
IENVMALRGDAVKSETYYKPNKNGNIYAQDLVEQIIDLNNGTYLDEDLQNSAKTDFCIGV
AGYPEKHLEAPSLESDIHFLKKKLEAGACYVVTQMFFDNQKYFDFVEKCRAAGITKPIIP
GLKPLATKKQLNLIPQRFSVDVPDTLVMEVVKASDAAAVRQIGIEWCIQQSKELQAAGVP
VLHYYSMGKSDNIRQIAAAVF
>A0A7X7W0Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKIIEMFRKKRPVLSFEIFPPRPDVPLDTIYDHLEQFEALRPDFMSVTYGAGGSRKGRTL
EIAARIKDLHGIESMAHFTCAGHTREEIDNMLEAMHRSGLENILALRGDPPADQPDFDFS
RGAYRYASELVQHIRKVNDFCVAAAAYVEGHVDSRRLSEDLRHLREKVDAGVDFLITQLF
FDNRLFFDFLEKARAIGIECPVSAGIMPVFRADQIKTIALKSGCSIPAKVVLMMDKYQDD
PEDMRKAGIEYASLQIRELVSEGADGIHLYTMNRPKSTREIISNISDLTGIPSGGADAH
>A0A7X8PZK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKILDLFKEKKTVISFEIFPPKFDTPIETIFDTLEQFKNLTPHFISVTYGAGGSAKDRTI
EIASKIKNEYSIESMAHFTCVGHSKEEIDKLLQSLHDNNLENILALRGDPPIDQPDFDFS
KNTFEYANELISYIRSKNDFCISAAAYVEGHVNSARLKDDLRYLKQKVDTGVDFLVTQLF
FENRIFYDFLDKTAVIGINCPITAGIMPVFKADQIKRIASMCGASIPAKLVLMMDKYCNN
AEDMRKAGIEYASKQIRDLIDNGVDGIHLLTMNRPKSSKEILENVGVL
>A0A849DXD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiritimatiellales bacterium|TrEMBL
MKNILDLITKRPLIFDGAMGTVIYSKGVFINTCYEHLCITNPGLISGIHKDYVVAGADVI
ETNSYGANRIKLEAHGLVDQLEAINRAAVRLAREAAGDEVLVAGSVGPCLKSNQLYVDHL
AAEMEETFREQMAILADEGIDLFLLETFTHAQEAQLAAAVAREFGVPVFVSVTVGKDGET
RRGEKIEQMVRAFDADANIDGMGINCGMGPAAAFSIAERALPHTGKPFTVMANAGLPQEV
DGRMIYMSTPEYFTEYGKSLIQIGVRGVGGCCGTTPEHIAMLAKSVKTMTGVKQHVLIES
HTDQKMPEVNVIPMAEKCAFGAKLARGEKVTSVEITPPRSIDLQPMLDKCQTCKKAGIDA
INIPDGPRASARISPMVSALAVEREVGIETVLHYCCRDRNLIGMQSDLLGGYAGGLRNYL
IITGDPPKLGDYPDSTPVFDVDAVGLTQVVTNLNHGVDVGGNPINPPTGLLIGVGANPCA
VEPERELQHYMNKIHAGAEYTITQPVFDPEALLRFLDAAEARGGTIPVVAGVWPLVSLRN
AEFLANEVPGVEVPDAILERMSTAKTKEEGRELGVEIAREICERIADRVAGFQVSAPFGI
VDLALQVLK
>A0A1Q6ZUF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium 13_2_20CM_2_69_23|TrEMBL
MTITLSDLLKDGKVHVLDGAMGTMLYSKGFLLNVCYDELNLKQPKLVQEVHEAYVRAGAE
VLETNTFGANPVKLRSFGLADETEQINQAAVRLARAAAAGRASVVGAIGPLGVRIEPFGA
LARDEACAHFSRQVKGLLAGGVDGFILETFSDVEELHAALRAVQGLSDLPIIAQMTIGDD
GLTHYGTGPETFAQQLTEWGADVIGVNCSVGPAGVLEAVEKMVKVTDRPISGVPNAGLPR
DVGDRKIYLASPEYMASYARRMIEAGARLVGGCCGTTPEHIKKIRDYVASVVPRHQPAVV
SRETIAVPAGVEEVPLAARSRWGAKLARGELVTSVEIVPPKGVDATPMLEQCRALKAAGV
DAVNVPDGPRAQSRMGVLPSAILIEREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRN
ILIITGDPPKMGPYPEATAVFDIDSIGLTNLVFRLNHGLDPGNNPIGAPTRWAIGVGVNP
GAVDLDRELSRFAWKVDAGAEFAVTQPVFDPAQLEAFLARVGQFKIPIVAGIWPLISLRN
AEFLANEVPGVSVPESVLARMRQAQEKGKEAALAEGVKIAREMFQQVKGSVQGVQVSAPF
GRVEVALEVFG
>A0A4R5E5K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea mesophila|TrEMBL
MPFRGTEDAVLAYVPRTIPLTVTTTEAKGLAATVDLAGRLAGHGYSVAPHLAARQVRDGR
HLAGLVAELREAGIDGIFVIAGDVAQPAGGFPDALSLLEALDANGHHFRHIGIGGYPEGH
GSIRQELIDRAIELKARYATHVITQLCFDAATTVAWARRLRERGVELPIHVGLPGAVSRQ
KLIRISAGLGLGQSARFLRKQQNLFWRFFLPGGYSPDRLAERLAPRVYDPGSNLRGFHLF
TFNELEKTESWRRTMLIRAGYHT
>A0A371B8W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudolabrys sp. GY_H|TrEMBL
MHMKAASATVARRFSIETTRPKPAEIDAVAAAVPKGTEFYITAVPTQTEDELVAAAAHAR
SKGLEPVVHVAARRLPSVAMLQERLARLHAEADVRRLLVIGGDIDPVGPFADALAVIQKG
KLRDAGIEKIGIAAYPEGHPAIPADRLAASLDEKIAAAVAQGLEVRLVSQFSFSPDDIVA
WLKKLRATGITQPVSVGMVGPTSVPALLRFAKRCGVGTSLKGLMSGAASALIGNVGPDRI
IEALNAEQATVGDVQPHYFTFGNLVATAEYGSAMAGKEIAAA
>A0A371BB80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudolabrys sp. GY_H|TrEMBL
MISQLRPSRFMPAGHNRIDVSFEFFPPKDEAMEATLWDAITRLAPLMPQFVSVTYGAGGS
TRERTHATVKRILAETALTPAAHLTCVAATREEIDGIVRNYHDAGVRHLVALRGDPITGA
GDKYTPHPGGYENAAALVAGIKRIAPDFEVSVSAYPERHPDSPTLEADIDTLKRKVDAGA
TRAITQFFFENDLYFRYLDRVRARGIDIPIVPGILPVQNFGAARNFAARAGATVPAWLAE
RFAGLDHDPATRKLIAAAVAAEQAIDLLDRGITSFHFYTMNRADLVYAICHLLGLRPQVQ
EAA
>A0A5C4NGI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubellimicrobium roseum|TrEMBL
MPTVSFEFFPPKSLEGSFRLWDCCNVLGPMGPEFVSVTYGAGGTTRELTHEAVGTIHKHY
GLTVAAHLTCVDASREETLAIADAYAAVGVTEIVALRGDPPKGAERFSAHPQGFASSVEL
VEALARTGKFTIRVGAYPEKHPEAADARADIEFLKRKIDAGATSAITQFFFQPETFFRFR
DACAKAGITAPILPGILPVESWAGVKRLAGRCGTHIPETTAHAFENAERDGTTELLAVAV
ATSLCDRLIQGGAEHLHFYTLNKPGLTRDVCLALGIAPKARLQAVA
>A0A1W7M5P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. MD-1|TrEMBL
MTTSYDQLREARTALDTPLFAGLPGDIRVSFEFFPPKTDALMTQLWDVVTTLAPLEPQFV
SVTYGAGGSTRDRTHGTVARIISEARLPAAAHLTCVDASKAEIREVAEGYWDAGVRHIVA
LRGDMGAPGVPFTPHPEGYANAAELVAGLKAIAPFEISVAAYPESHPDSPSVQADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAAACGAA
IPAWMDGLFEGLDTHPASRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPGRPALEKAA
>A0A3D1LR18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
MKIIDKIRPGNQFISLEFFPPKGHSEWPAFFQTVERLAGLDPLFASVTYGAGGSTHGDSL
EIVTRLQKEYALETMAHLTCIGSTPDEVKSFLDALAGAGVENVLALRGDIPQDAKAGFTP
SPLLGHASDLVSLIRSSRPALGIGVAGYPEPHPEALSPESDLAYLKLKLDNGADFAITQL
FFDNDLYHDFVQRALSAGITKPIIPGILPVVSLKVIKRIVAMCGGTIPAEFMARLEEADR
RGGAAAVQQVGVAHARNQIGQLLEAGVPGVHIYTLNRAEVVLELVDGLLQKEWKS
>A0A3G8WP08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium taklimakanense|TrEMBL
MKITDHIKKANGKTLFSLEVIPPTKGTGIEDLYKNIDPLMEFKPPFIDVTTSREEYVYIE
KGNGLMERKITRMRPGTLGICASIQHKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
VMALRGDAMKGQNQFLPTEGGHHHAIDLVHHINDIGRGKYLTDEKRCDEENKFCIGVAGY
PEKHIEAPSMNYDLQKLKEKVDAGADYVVTQMFFDNQKYFNFVKEAREIGIEIPIIPGIK
PIATKGHLSMLPKTFKIDLPEELISEITKAKDNTAVKQIGIEWAVKQCRELLDFGVPVLH
FYSMGKSDNIRKVASELF
>A0A651H9P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceicoccaceae bacterium|TrEMBL
MPDPAIASLFTPDRTICSVEFYPPKDDAGVQALRETAATLQELQPDFVSVTYGAGGSTRA
RTAEVVRLLREEFGYLVMPHLTCIGSSARELTDLVADYHAAGIRNLMVLRGDLPKSGAAF
HPSPDAPRFAVDLVRLIRRHFPDICLGVAGYPETHPEAPDAATDLAHLKAKVEAGGAFVT
TQLFFNNAHYTAFVDRCRQAGIAVPILPGIMPVLSLKQIRRFTAMCGASLPEALVRRLEA
AEREDRSLPAEGVEWAAGQLQSLLQGNAPGVHLYVLNRAAAALELGSRLAPLLGR
>A0A371BC50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudolabrys sp. GY_H|TrEMBL
MDTLQQKLAAGRFVITAEITPPVSFDRADLSAKAAPLKGLADAVNVTDGAGARPHMGALA
AAAILIQDGIEPILQLTCRDRNRIALQSDLMGAAALGIQNLLILRGDDPSAGDQPDAKGV
FDLDARGLIETARKLRDDHELPGGRKVAGTAAFFLGAADAPIDPPPGWEPKGLAAKAAAG
AQFAQTQFCMDPDVVARYTARLAGHGLGHLKLIVGIAPLRSAKSARWMREKLFGTIIPDA
TVARLEAAADPAAEGRAIAVDLIAALAANPGVAGVHIMAPNNDEAVPPVIRAARASIKRL
SA
>A0A1Q7C9I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_2_20CM_2_66_6|TrEMBL
MRIADMLVGGRPTVSFEFMAPRDESEVDALEKTIAALAGHAPDWVSVTYRKATGDKTLEL
VTRIKRQYHIEAMAHLTCANTADETRRILNWMEREGVANVLALRGDPPGPGAPFQPTDPQ
LMHGSDLVSLIRGSGYRFGIGAACSAEKHPESPDLDHELRYMQLKVESGADFLITQLFFD
NRFYFDLVRRASESGVELPIVPGLMPVPSRRSLAFMTSMAGATVPAGLESEIAAAADDEA
VRAAGVRHCIAQCVELLEAGVPGLHFYTFNRARAPMEILAALRGQQLLTA
>M4NHI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter denitrificans|TrEMBL
MPSISFEFFPPKTDEQRAQLDRAAQVLKAHQPEYASVTFGAGGSTLSYTGDTVARLHTQH
GLNVAPHLSCMGGTRAEIAALLDGYRASGYRRIVALRGDMPSGMASAGDFRYAAELVGFI
REHCGDHFHIEVAAYPETHPQADDALRDLQHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VRRLGVEVPIVPGIMPIANFSQLKRFSDLCGAEIPRWIAKRMQAHGDDADSIRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRARATQAVLQQLS
>A0A840AUH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingorhabdus rigui|TrEMBL
MILPFDQMQEASRALAAPLFAGLAGDCEISFEFFPPKTEKMEEQLWDSVVTLAPLAPRFV
SVTYGAGGTTRERTHNTVARIARETNIPAAAHLTCVEASKGEIADVANAYWDAGVRHIVA
LRGDPPSSDSKFVAHPDGYASAAELVEGLRKLHPFEISVSAYPETHPEALSAASDIDFLK
RKLDSGASRAITQFFFEPETFFRFRDAVAAAGVDAEIVPGIMPVSNFAAITRMSAMTGTA
IPVWMAHLFEGLDDHPPARQLVAATVAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GKRPAGAAQEQAA
>A0A290ZRH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera sp. K11|TrEMBL
MAERGNHLARALAGERFAWLLECIPAAGRRPEADYGALIGPRGAPDWLSAFAVTDRVLSP
QDPDPLPIAGRLLQASGRQPLLHFAGKDRELAELRDRVRTMQQMGLRNLLLLSGDRLPGH
GHGKRIRYLESVAAVAAVRRWQPDWLLGVAVNPFKYREEDGMLQYLKLSKKLRAGASFAI
TQVGFDPDKHVEALGWMADSPLRRPLLACVMPLSAARARHLRRYPVPGITVSDSLLALLE
EDARRQPDGGRARVLHRLALQIVHLRRLGYAGIQLTGIRNAMDLQALADSVDALARDCAD
QAAWESAWRDHWCRADGTPADPRPPGECWRPGQGTVRASPRERYRYRVFAATHALLFQRG
PLAAAFAWTMRAACAQPGTMARGLERLERAVKHPLLGCETCGQCRLASTQFVCPETCPKG
LANGACGGTTQNRCEFGEQECIHSVRYRIAKETGALNELESVLVPAIPAETRHSSSWPAW
FIRQEPHVRILDASAPGTSIDTAGAPTCPHYGPDA
>A0A7T5EYT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicyclobacillus sp. SO9|TrEMBL
MTASRAEFREWIAHNRVVGDGAMATLLHQMGVPVRTCYEELCISKPWLVEQVHREYVSAG
ANIIQTNTFSGHAAGLDRYQLADRVQDINRAAVDIARKAATGDVRVFGTIGSIVGLTPGL
MTWDAESKAKLGGAFSEQMQALLLEQPDGLLLETFADLNELLLAVTTARELTNLPIIANL
SPEVVGVTRDGVHLVEAFPKLIEAGADVVGLNCRLGPEGIARSYAELSLNETVGYAAYPN
AGMLQREGNEVSYTANPDYFSNFAHDMYQLGVGLVGGCCGTTPQHIRAIAAVRDGTVPRS
TSGIAGKPRPIMHREVEGRHEAARPESLPNTSSLVKTTGGGTTVIVELDPPRTLNTDKFL
TGAKALTAAGADFITLADNSLGHVRVSNMALASQLKQLGMNPLVHIACRDRNLIGQQSHL
MGLHVLGIHQILLVTGDPSRFGDLPGASSVYDTSSMELTAMVKRLNEGIAFSGQHLKHAS
KFEVGTSFNPHVKNVDRAYERLQKKVAAGADYVLTQPIFDARRFEEIARRTKDLGVPVFV
GIMPLVSSRNAYFLHNEVPGIDVSDEILHQMGEVDSEAGEKVGLRIAKHLIDEALKHFSS
IYLITPFLRYHLTVELVEYIRSSKNQLVK
>A0A7U8QGH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae PID18|TrEMBL
MNYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGDRDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A520M6L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thioglobus sp|TrEMBL
MPIDTATQTVSALKSGSNLEKVLAGGHFAVTGELGPPKHMDTTVVDRKIDLLKGAVDAAN
VTDNQTGIVRLSSIATGIYMAQHGLEPVIQMTCRDRNRLAIQSDLMGAYIHGIRNVLCLS
GDHQSFGNHPGAKNVQDIDSMQLIRMLQEMRDKNQFQCGDEIKGGGPKLFIGGAGSPFSE
PISFRPLRIAKKMAAGVDFIQTQMIFDMNIFRQFMSRLVDLGVTEKVHILAGIGPLKSSP
MARFLNEKIPGIIIPEDLLKRMDGAVQGISEDDKEGRRDAWRAEGQNICIEQIEELRQME
GVSGVHIMAIEWEAAIRPITERAGLLPRPIV
>A0A4Y1WKU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes onderdonkii subsp. vulgaris|TrEMBL
MNVVDIINKAISERRTRFAFELLPPLKGDGCCGVFGSIDRLIGFDPAYINVTFHREGIKQ
AVRPDGSVEWHVVRRRPGTVGISAAIQKKYGVEVVPHLICGGQSKYDIEDALIDLDFLGL
HNVLALRGDKSQNEKFFMPHPQGHTHAVDLVRQIAAMNRGQFVDGEVEECHHSKFSIGVA
GYPEMHEEAASPEADIACLKAKVDAGAEYVVTQLFYDNARFFDYVRRCREAGITVPIIPG
IKPLSTVRHLTLLPQTFGCHIPEELGREVLRHKDDPKAVREIGTEWAVAQSRELVEAGVP
VLHYYPMGKADNIIKIAKAIF
>K0ZHH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. GMD6S|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A0H1BLC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomyces silverae|TrEMBL
MEKISDKIAALPRDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTYAVDLVKYIRRTHGDYFCIGVAAYPEGHSDESYPEVQDPARDLPYL
VEKTRAGADFIMTQLTYDLEAYKRFENMLRTHESGVFKTIPIITGLMPIQSYHILTRTTK
LSHARVPPSIMARVEEVKSDDESVKRIGVDILCEIVNGLKEIPCPGPRGLHFYTLNLEKT
VAFTVERCNLIPPSSEPSSDSETDLDTAVSMVHGQLNNLVRMSKRRASSINSQPHNRLIV
DRPSDGRGSSQASTTHETQALGAGMPALNPPHRATALQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVNATVARRLWGYPTTKEDINTIFRRHVSGELHIVPWSEGGT
QDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAF
VEFFCTAHDLKTILKPIFENHGHDELAWFATNIAGDFESSSPPSGDSANDYSGPVDVYLD
SNATSGGTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRVFPRGSPTER
LLDQLKNDVWLVCVVGQKYGAGCQSKEAAEAEGKLLWKLLAGQDTGAGSANKH
>A0A2I1P6Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNATGVFNHASDL
VSYIRSQRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A4Q1U614|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. Tri-39|TrEMBL
MMNAFRPSRHGSRRPRVSFEFFPPKNEEMEVSLWESVRRLEPLGPAFVSVTYGAGGSTRE
RTHNTVKRMVDETGLKPAAHLTCVSATTDEVDEVIRAYWAAGVRHIVALRGDPAGGLGST
YEPHPQGYHQTSDLVAGIRKVGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAI
SQFFFDNDVYFRYLDKVRARGIEIPILPGIVPVQNFKQTANFARKTGASVPQWLADRFEG
LEDDAATRRLVAAAVCAEQVLDLIDRGVSDLHFYTMNKADLVYAICHLVGLKPEKAQAQQ
VAAE
>A0A0H1BQ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomyces silverae|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPRENVDAALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCEDQDDPELLMEHLKEKVDAGGTF
IITQMFYDVDIFLTWVEKCRENGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEAL
EPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQATKMILDELGLIPSHKTP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSLKELSEIFVRFLDGSLDRLPWSEGAVTEETEIIKPDLLE
LNRKGFLTINSQPAIDGMPSSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVINRIEQNS
DLTYYCVNKQGELKTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHASSSPSRRLIEQVMDSWYLVNIVNNDFHKTHDIFNLFKDLKVENLDTEVEPIAPAAE
PVDNAQQNGQPPQTEVNGSFTEATKSMQERNSN
>A0A3G5KEL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pseudotuberculosis|TrEMBL
MKRKISFEMNSAKNEKEMENIFKLIEFTDTLDPIYYTVNTEIGSSVWSDTYRTVIELREK
TDVPLIPHITINNKKEREIMQIIEKYINVGICEFFVIRGDKHVYDQDNPINYGVELIELI
RRSHKHIGIKTSLYPDFHKETTEVKEEIDWNERKYQLGVNEFISQLTLNTNALDFLSHWV
DKERPFTPSIMPLGNFSFIEKFTSSNSIDYPLWIKKFANSKSNSNEDKENIGIEIIRFLC
REYLNQRERLHVFTLNKVDVMKKIFQ
>A0A672HC52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salarias fasciatus|TrEMBL
MVNQKQRVEGAWQSSKSDSSNSTSGGESSKESSRCSTPVLDADRSDRLRDKMRRRIESGD
CWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQTREVITGHLAKAKHLGLKNIMALRGDPMGTDWEEEEEGFNYAVD
LVKHIRAEFDSYFDICVAGYPTGHPEAESYEEDLLHLKEKVEAGADFVISQLFFRADTFL
KFLDDCRRIGISCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITEVIEPIKDNDAAIRNY
GIHQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELMNEESVFEVFTSYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELDKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVSALLKVLKKYEPRVN
YHIVNVHGLNLTNAPELQPNAVTWGIFPGREIVQPTVVDPVSFVSWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELINESLEQLRDSGDRL
RAPGEQLGASGDQLGASGDGIGASGDGIGASGDGLGASGDGLGASGDGLGASGDGLGASG
DGLGASGDGPSGDQPHRDK
>A0A6L6WI94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zongyanglinia huanghaiensis|TrEMBL
MTTPEISFEFFPPQNLEASFRLWDTVQVLSPLDPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNASRAETLAIADQFASAGVNDIVALRGDPPKGAGGFTQHEDGFANSV
ELIEALADTGKFNIRVGAYPDRHPEATGPDSDVDWLKRKIDAGASEALTQFFFEADTFFR
FRDKCAKVGIDHVLTPGILPIENWKGARNFARRCGTVIPQWLDDAFETALRDGREDLLAT
AICTELCSELLDGGVGKLHFYTMNRPELTRDVCHALGVAPKVSLENVA
>A0A1G9I512|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halarsenatibacter silvermanii|TrEMBL
MPEYISNLHKLLEEDHFVVCSEMGPPIGADPDFIREKCEDLHGYVDAVNVTDNQTAIVRM
SSIAASKIAHEEGLEMIIQATTRDRNRIGLQSDLLGASALGLRNVLCLTGDHQSFGKDEG
SKNVFDMDSVSLIKAARDMVDDEELVSGDELRTPPKLYIGGAHNPFAEPYEMHMLKLKKK
IKAGMDFIQTQCIYNLEKFDRWMEDMRKEGLHEEVHILAGLLPTKSEFALKYMKNDVPGM
DVPDELIDRIANADDKRQEGIDFTVEIIEHVKNTEGVKGIHLMPVGWEEITPVVVEEAGL
YPRPEVEVDDE
>A0A0W7WXW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces silvensis|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNSLRRVEAVAPSFVSV
TYGAGGSTRAGTVRETQQIVADSTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLALR
GDPPGDPMADWVKHPEGLDYAAELVRLIKESGDFCVGVAAFPAMHPRSSDWETDVRHFVD
KCRAGADYAITQMFFHPEEYLRLRDRVEAAGCETPIIPEIMPVTNVRQLERLPQLSNADF
PAALKERILSSKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHPQA
>A0A239C204|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium subroseum|TrEMBL
MALGRPSILPDRVPTVRELLAAGGRSFSFEFFPPKTDEGERQLWRAIRELESLHPTFVSV
TYGAGGGTRDRTVDVVERLAHETTLTPVAHFTAVNHSVRELRHLIGRFAGAGVRNILAVR
GDPPGDPMGEWVPHPEGVLYADDLVRLIRQSGDFCVGVAAFPYKHPRSGTVEADTEHFVR
KCRAGADYAITQMFFEADDYLRLRDRVAAKGCDTPIIPGIMPVTQMSTIARSEQLSGAPF
PPRLTARFEAVADDPAAVRELGIEHAAELCQTLLDEGAPGIHFITFNRSSATREVFQALD
FAPKAVSLAGR
>A0A150UH60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. AT1|TrEMBL
MTDLTRSARADGQDGHPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAGGST
RERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAGGIG
TPYASHPDGYQSSAELVAGIKKRHADIEVSVSAYPEKHPEARDFDDDIDTLQAKVDAGAS
RAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRAGTTVPDWFAAK
FEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAKSAQ
KAA
>A0A512RQ66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga cymbidii|TrEMBL
MAELAAFIDNPYDAMSNSLADKINTGNSRLIFYSLTPPKVTTAPERIAEIAKGQFERISQ
QDIDALILYDIQDESSRTEQERTFAFISTVPPEVYSREHFQQLEVPKIIYKSIANFTGAQ
FSEWLTQNVDIKQSVFVGASSQKQVEKTNFSLQDAFGLRQQVSPELLIGGITIPERHAKK
GDEHLRIMQKTLQGCSFFVSQCVYNVNDTKDLLADYYYHSCGQGIAPAPVIFTLAPCGSL
KTLQFMEWLGIKVPKWLYNDLKHSKDILESSMHTCLNVASEILEYADRKNMPVGFNIESI
SIKKDEIDASMELLNGVIRMAKRPVEAVV
>A0A504UL98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium glycinendophyticum|TrEMBL
MAQTARPNSADLKVSFEFFPPKSPDMADQLWQTVKALEPFQPDFVSVTYGAGGTTREPTL
DTVGRLIRDTSLATAAHLTCVAASRQEVRQVVDEFKARGVKHFVALRGDPQGGVGTRYTP
HPDGFENAADLVRGLQDMGEFEISVSAYPEKHPESINDAADIDMLKRKVDAGATRALTQF
FFDNDLFEQYLNRVRSAGITIPVVPGIMPIQNLAQLKRFASMCGASVPERLDHRFEGTDG
DPQARAEVAADVAAEQIVDLAKRGIEEFHLYTMNRAPLTIATLERVGLGPKSRRNVSGAA
A
>A0A1G9QX57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces wuyuanensis|TrEMBL
MALGTASTRTDRARTVRELLETGKTSYSFEFWAPKTEKGERNLWNALRRVEAVQPNFVSV
TYGAGGSTRAGTVKATQQIAADTTLTPVAHLTAVNHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPDGVRYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWETDIGHFVD
KCRAGADYAITQMFFRVEDYLRLRDSVAEAGCETPIIPEIMPVTSVKQIERFAQLSNASF
PAELEQRIRAVADDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQQS
>A0A150GQD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gonium pectorale|TrEMBL
MPVQELRTPVCRTRSKEYGDYFGICVAGYPEAHPDGIVEDPEQMDKNYWADIAYLKQKVE
AGADFIITQLFYDVDIFVKFVADCRSVGITVPILPGIMPIMTYGGFKRMTGFCKTKVPAE
ISDALEAIKDNDEAVRNFGIDLGVTMCRRLMEAGTPGLHMYTLNLERSAVAILEKLGLVD
TKGVPRSLPWSHVPQGTSRAVEAVRPVFWSARPKAYLRRTQGWPAYPAGRWGDVSPAFAE
LPDSPFMRRHSGSEKAREKARAAWGAALAGEEDVRAVFSKYAQGEISLFPWSEGEGGLSA
EAAPVRDTLAALAAAGYLTINCQPAVNGAASTDAVHGWGAPGGYVYGKSYLEFFVSPAAW
ESLRSRFDAAPSVSYVASTSSGSPSGSLAAGDVVGLKWGAFPACSRTDSVSPGPAPARPA
PPARRPHPAPTSRPRPPAPAPIPTPHGKEVIQPTVLCATSFGTWKDEAFALWSSEWAALY
EGEEGAASRQVLEGIAGSWVLVAAVDNDYVTGDLAKVILG
>A0A1Q5TLA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium subrubescens|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRALVDMALEEAKVLGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRKQHGDYFCIGVAAYPEGHPADSFQDVQDPVRDLPY
LIEKTVAGADFIMTQLTYDIEAYQKFENMLRNHESGVFKTIPIIPGLMPIHSYKILTRVT
KLSHVHIPDPIAKRMEELKHDDDAVKRAGVDIVSEIVGGMQELKSPGPRGFHFYTLNLEK
TVSFILERCDLIPASTDIEDDYAIVEADGVVPLGASARLARRRASSINSQPHNRVIVDKL
SAKESSHDSVHEALANSVGQPAMLPGRGTTLQISEGLGSLGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTSAVARRIWGHPVEPSDISTLFRRHVSGELYMVPWSEGGAEEGAGL
NAETELIRPELLKLIDGRGWWTLASQPAVNGVRSDHHIFGWGPQREGFVFQKPFVEFFCS
SSDYNTILKPLFEKHGHDKLVWFATNNTGAFESSLPTQPADVELDELNDNPESVNAVTWG
VFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTERFLDTTKNDTWLVCVVG
QQFGAGTPRGSKEEEDEVKWMWRVLAGETQ
>A0A2U0DJZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. HMWF035|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICASIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHGSAMELVHQINDLGRGKYLHNQDEICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEDLINEVENAKNNEAVKQIGIEWAIAQCRELLEFGVPVL
HFYSMGKSDNIKKVAGALF
>A0A0F2JHZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp. I2|TrEMBL
MAEEKSKLQSLFEQGEFAVTCEIGPPKNAQGDGIRKHTEHLKPFVDAVNLTDNQTAIVRL
SSIGAGVHVLAAGGEPIIQMTTRDRNRIALQSDLLGAYSLGVRNVLCLSGDHQTFGNHQE
AKNVYDLDSIQLIKTVKDMREAKVFQSGEVIKQGEPRFFIGAVANPFADPFEFRVLRLEK
KIRAGAQFIQTQCIFDMERFEAFMDLARKRGLHQQAYIMAGVMPIKSAKAAKYMQKNVSG
MLVPDGIVEKMSKAEDQPAEGVKLCIEQIKHLRTIPGVRGVHIMAVAWEEIVPEIVKGAG
LLPRP
>A0A2A7TYB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edwardsiella tarda|TrEMBL
MSFFHASQHDALNQSLAELQGRIQVSFEFFPPRTPEMEQTLWQSIDRLSTLKPAFISVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCVDASREALRAIARDYWQSGIRHIVALRGD
LAAGAGRPEMYASDLVALLREVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIEAEIVPGILPVSNFGQLQRFAALTNVRVPQWMMAMFD
GLENDVETRKLVGANIAMDMVKLLCREGVKDFHFYTLNRAELSYAICHTLGVRPQA
>R6ELA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:65|TrEMBL
MDFFVFETFSEMEELLPAIKMIGEQAFITVQFSVNQFGYSNAGLSARKLLQRAGAIKEID
AVGFNCGVGPSHMYRILQTLYKPADKFLTALPNAGYPQMVTGRMIFTGDNREYFVDRMQQ
MIALGVDMAGGCCGTTPEYISDLAGKLDFTQYPQTQEKAEPEKKQAGTENHSFYHNKEAE
GGKKLIAVELAPPAGIDDEKLMDAAHLLQRSGVDVLTFPDSPSGRTRADSILMAEKVARE
TGMCVMPHICCRDKNAIAMRSQLLGAYINGIHNFLVITGDPIPSMVRTTVKSVFNFDSVG
LMQILADMNEEQFARAPVSYGGAINQGRRNLEVEIGRVKKKMAAGATFFLTQPISTKESA
DRVRRIKEETGARILCGIMPFVSLKNATFMKNEMAGIDVTDEVLARYRADMTREEGEQAG
VQLAKEVIAMTEDFADGYYFSFPFNRVTMLEKILD
>A0A2G1QPN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zhengella mangrovi|TrEMBL
MIDSPDTNPLDPSAPLDPLPGHVSRGRLERVLRRGEFAVTAELNPPDSADPQEVYDRAAI
FDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAM
GVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDEQRFLSGRPITSPPHVFLG
AAINPFAPPYDFRPHRLAKKIAAGAQFVQSQYCYDVPMLREYMKRVVDMGLHEKCFILVG
VGPLASAKTAKWMRSNVPGVHIPDAVIKRLEGAEKQKREGKRLCIDIMNEVKEIEGVSGV
HVMAYRQEEFVAEIVHESGVLKGRKPWHRESRPDDAVIAERLEEIMAEETERPAAIVADV
VDSN
>A0A1Q1EVA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus sp. RS01|TrEMBL
MKSKLQQTLEKRSKVITAELMPPRGGSPIRSLKIAQLLKDKVHAVNITDGSRAVMKMCSL
AMSKLLLENGIEPIMQVSCRDRNKIALQSDILGANALGIRNILCITGDSVKAGDQQDAKA
VHEFESVRLLQQIQSFNQGIDPTLGELSDKKTFIFAGAAADPNCRNKRSLENRMRKKKEA
GAGFIQTQMVMEKENLIEFCEKISEPLEIPVIAGVFLLKSYKNALFINKYVPGADIPENI
LNRLKDAKEPLQEGIKIAAEQAHDFMNIANGVHIMAVKSEHLIPEIIEKANLSLEY
>V4XY30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium MOLA814|TrEMBL
MLPISFEFFPTKTPEGAANQRDVRKALYAKKPEFCSVTFGAGGSTQVGTFSMTQEILDEG
VCAASHFSCVGATKASVRDQLVTLKTMGVKRLVALRGDLPSGYGAGGEFHYAIDLVTFIR
AEFGEDFHIEVAAYPEVHPQARNAQADLQAFVDKVNAGAHSAITQYFFNTDAYFRFVDDV
YKMGIDVPVVPGIMPITNSAQLMRFSDMCGAEIPRWIRLRLQGFGDDAASIKAFGHDVIV
DMVDQLKNGGVPGMHFYTMNKSAPVLAICDEVGL
>A0A0G3QEK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytobacter ursingii|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRAIAKDYWDNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCASTGIDVEIIPGILPVTNFKQAKKFADMTNVRIPAWMSQMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A2N8ELI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FW305-131|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAIYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKEDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKAKAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A165JQB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. GW101-3H11|TrEMBL
MNAANAQGTGFPVSFEFFPPKTPEGAEKLRVARQQLYVLHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVGAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLKAYVAKVQAGADSAITQYFYNSD
AYFRFMEDTQRLGANVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A1E4FEY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterium sp. SCN 63-23|TrEMBL
MIDDNLRASRQTADQRPDLQLSFEFFPPKTDVMEERFWDSIQKLAPLHPRFVSVTYGAGG
STRERTLRMVSRIEADTGVSAAAHLTCVSATREEVDEVVRGYEAAGVNRIVALRGDPPEG
VGHPFTPHPQGYQNAADLVAGIRRIGDFDISVAAYPEKHPQSADWDADIDNLKRKLDAGA
NRAITQMFFSNADYLRYLERARKAGVTAPIVPGIQPIHSFKQISGFAARCGASIPGWMAE
RFEGLDDDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRP
>A0A2D8WC60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MKSMIEDGLVHIFDGAMGSVLYTRGVFVNICFDELNLSNPEIVRRIHQEYVSAGSEILET
NTFGANPVKLSSHSLGDRTEEINEKAAHLARDAGAGRVAVVGAIGPLGIRIEPWGPTARA
EATAFFERQVNGLLAGGVDGFILETFADLNEIDXAFTAXRKLGDLPVIAQMTLGQNGKTV
YGHTASQIAQELTSIGXDVIGLXCSVGPAVMLDAIEDMADXTSVPLSAQPNAGLPRTVRD
RKIYMATPEYMAQYAXRMVDAGXRFVGGCCGTTPDXIKQIRDXVRSXQPXPVMVRVTDVD
QEXSXXXDPVPLEACSXWGRKLSRGEPVVSXEVLPPRGWDRNAIVXPAHELKDAGVDSLA
IVDGPRSRSRMGALSAAVIVEQEVGIEAXVHYTCRDRNMLGMISDLLGAAAAGIRNLLVV
SGDPSVHGPYPDMTEVFDIDSIGLTNVVTGLNQGXDPAGNSIGDPTKFVQGVVAXPGALD
LXREVTRFRYKVEAGASFVVTQPIFXPESLEXFLXKIHQWKIPVVAGIWPFLNLRNAEFL
ANXVPGATVPEKIVDRMRXAQISGDEEALNEGVEIAAEMIDAVRPLVQGFHLXAPXRRVD
VALRVLXEAGVSTNT
>A0A2E7U2F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MKSMIEDGLVHIFDGAMGSVLYTQGVFVNICFDELNLSNPKIVRRIHQEYVSAGAEILET
NTFGANPVKLSSHSLEDQTEEINEKAAHLARDASAGQALVVGAIGPLGIRIEPWGPTGRA
EATAFFERQVNGLLAGGVDGFILETFADLNEIDCAFTAIRKLSDLAVIAQMTLGQNGKTI
YGHTASQIAQELTSIGVDVIGLNCSVGPAVMLDAIEDMADTTSLPLSAQPNAGLPRTVRD
RKIYMATPEYMAQYARRMVDAGVRFVGGCCGTTPDHIRHIRDSVRSDQPKPVMVRVTGVD
QEGLATLDPVPLEACSAWGQKLSRGEPVVSVEVLPPRGWDRNAIVEPARELKEAGVDSLA
IVDGPRSRSRMGALSAAVIVEQEVGIEAIVHYTCRDRNMLGMISDLLGASALGIRNLLVV
SGDPSVHGPYPDMTEVFDIDSIGLTNVVRGLNQGIDPAGNSIGDQTKFVQGVVANPSALD
LEREVTRFRYKVEAGASFAVTQPIFNPESLENFLDKIHQWKIPVVAGIWPFLNQRNAEFL
ANEVPEATVPEKIVDRMRKAQISGDEEALNEGVEIAAEVIDAIRPLVQGLHLSAPSRRAD
VALRVLQEAGVSTNT
>A0A7W5KK36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK049|TrEMBL
MALKSEGRGRNFGISFEFFPPKSEEMEAQLWDAVAKLQDWDPDFVSVTYGAGGTTKAPTL
SAVTRFLSQTPLATASHLTCVGATKEETHQMIDTFRKVGVKHFVALRGDAPGGVGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGISIPIVPGIMPIQNLTQLKRFAGACGAVIPAFLDERFAGFDD
KPEDRAKVAAEVAAEQIEDLVRRGIGDFHLYTMNRAPLVSAVLDNLGYSRRAAKSAGAAA
>A0A7G8E063|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. TAK9802|TrEMBL
MSTALQRAIEAGDQVLTAEVMPPRGADPSHMLAMAASLQGRVHAVNVTDGSRAVMRMSSL
ASCKLLLEAGLEPVLQMACRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAGDQADARP
VNEFESVKLLQQVDSLNRGVDPVQGTLPDGATTLFAGCAADPQSRSWSGLQRRLQRKQAA
GARFVQTQMVMDPEALERFQHELAGPLGLPVLAGVFLLKSAKNARFINRVVPGACIPDAL
IHRLECAENPAMEGVAIAAEQVKRYLGIVRGVHLMAIKAEERIPLILDRAGLSSLPG
>A0A7C2MSD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
SRKYAELGVDALNVSENTGSRVRMSCTALAHLIQSHTGMETILHFTCRERDLSSIQSELL
GAAALGIRNILALTGEPSTAGELPHVTSVFDVNATGLVRILHGFNHGYTITGHDIGQPTG
FRIGVTVNLAAEDLETEVAQFEERIEGGAHFAQTQPLYDLAIFERFRQRVGAFPVPVLVS
VLPLTSGRHAEFLHHEVPGILIPEALRRRVHEAPDPKQEGLTIAKEFIRQLRDQVAGVHL
MVQADHATVVSEIMSACAASASR
>A0A380L203|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus massiliensis|TrEMBL
MVGQSPSLSFEVFPPNPAVGNEKIFQTLKEMQDLAPHFISVTASNNKFNIEETTVRLADY
IHNDLSIPTIAHLPAVYLTKDMVSSILQALDRVDVHKILALRGDIIPDVAPKNDFRYATD
LIEFIRQEAPHFELIGACYPEGHPDSPNQISDIQYLKKKVDAGCSSLITQLFFDNERFYD
FQDKCVLAGIDVPIYAGIMPIINRNQALRLLKTCENIHLPRKFRAILNKYENDAASLRAA
GLAYAIDQIVDLVTQDTDGVHLYTMNNVETAHHIHQATKDLFHKSIT
>A0A8D1C5P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKH
IRSEFGDYFDVSVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLK
ACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GQELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMLIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>A0A286ZMK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRSVGFQPTPDASLTPRAHGKGVKGGAPPGAPVQKETPHRFDRM
GAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEVTGYLH
KAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKGHPD
AESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACSEMGITCPILPGIFPIQGYH
SLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTL
NREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDE
FPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQELTSEESVFEVFAHYLSGEP
NQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGWGPS
GGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGI
FPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMLIQYIHDNYFLVNLVD
NEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>A0A7X3UYE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MSPTPEIEARAALIELARSASVEVPTGQVPPPEVLARYVPSEAAVYVPFMPKGRWPDTIA
ACERVLAAGLEPVPHLSARSVRSADELGDWLSTLVEMGVDALMLVGGDRRIPAGPYADTL
ALLDSGQLAEHGLRRIGVTSYPEGHPLVSPADLDEALRRKMDYARATGTELWIVTQFVFS
ASPALAWLARTREAGCTLLVRIGMPGPVALSALIRYASRCGVGASARALKRKPGIARLAG
RWSPTPIALALARHLADHGNTPAVDIHVFTFGGLADAADWLSSLRAPTRAGTPDGVDETP
>A0A6I6JQU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribellus comscasis|TrEMBL
MKVIDIINNAKKTVFSFELLPPLKGNDTSKLYRTIESLTEFDPKYINLTTHRDEIEFKEM
DDGSIVKRTIRKRPGTVAIAAAIQHKYGIPVVPHILCGGFTKSETEHVLIDLNFLGIKNV
LALRGDGVKSQHVFKPESNGHSNAVQLVKQIKDLKEGTYLEKDLKNSTPLDFCIGVAGYP
EKHFECPNRELDLNYLKQKVDAGADYIVTQMFFDNKVYYDFVDKCREIGITVPIIPGIKP
INLKNQLTVLPKIFSIDLPAELASELAKCKNNEEARRVGTEWAIYQSKDLVAHNAPSLHI
YTYGISDNVKEIVKAAF
>A0A2E5GWX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MNNPPKENRNLQALISDGNVHVLDGAIGTEIYTRGVFVNRSYDGLNLENPELVQAIHKDY
VKAGAEIIETNTFGANPIKLSGHGLAEKTEIINKAGAQIAKKAASGSVEVLGAIGPLGIR
IEPFGPTAREEAQEFFGRQISGLIQGGVDGFILETFSDLNELEQAFISVRSQSDLPIFCQ
VTVGEDGQTVYGTSPEAVATEVSSWGADVVGVNCSVGPAVLLDVIERMVEVTNCPISAQP
NAGLPRIVADRKMYLTSPTYIGQYASRMIDAGARFLGGCCGTNPEHIYKIRESVRKITPS
TEKQQKTIRTVSHRIALEDKIPLANMSELGRKISNDFFISSMEITPPKGSDPTGMINQCK
KIKDAGADFISILDSPYAPGRMSSLPAATVVENQVNIETVVHYPCRDRNMYRMISDLLGA
AASGIHNLLLVTGRPPPTGPYQPTLSGIDIDSIGLTNIVHGLNQGLDPGGNKLDDRTDFV
IGARMNHLAMDQQKEISRLNWKVDAGIHFLVTHPIFSVQQLQEFLEKISDLSIPTIGTVW
PLRSFREAEYLHNEIPGIQIPQLIFDRMEAAEKQGDLEARREGIRIAQETFEAMRPLIQG
LQIKASDENFEEALELLHNINNSD
>A0A6B1CMW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MDNPTVPMQPFLAALHHRPLLADGALGSYLFALTGRVSEQNHLYEAFNLTRPALVRQLHL
EYLQAGAQCLTSNSFAANATYPSAVSIAELNAAAVRLAREAIDQYCQQAQYSDPLFVLGS
LGPPLPAAQAPRTASDLYRAQIEALVEGGVDALLLETFTCLDQVAALLELLQDLDNPVPV
IVQMALHQRDGTWEQAPQAYIQTAASLGADVVGINCCALAEARAFLDAAQECASVRDGQV
QLAVMPNGGEFRRVGHRYLTGVNPECMGRFAREMAHKGVRLIGGCCEVHPSHIHEMHNYL
HGLAAGERIVPLARTPDQQPIDATAKRRNGPFSRKLIDGQFAVSVEMLPPRGTGGLKARL
AFIAELAASGLADALDITDGSRGIPLMPPGDFIHLIRRRLHWERDRLELIPHCTSRDLNV
MGLQSRLIGYWANRIHNVLFITGDPPKMAPTYPRSTAVFDLDSAALIRYTHAFLNAGLDF
GGQPLGTHRDPRTHFTIGTGCEPEALDLQREWERLAHKIDAGADYVMTQPTFDRKALAPL
TTYRAQVPIIVGVMVLRGLEHARRIAEVPGVIVPEAIFAKLSAYADPADQTKAGVELAAE
QVRQVRAEGWSGLYLMSPAGHQPVLEVLKRGLG
>A0A7Y3E228|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MSLFSPRRYQAPFRPCRTAEDGFFVRAFTRVERLIKEPLFGCRMCGNCILEQTALICPMT
CPKGLRNGPCGGATPDSCEVDPSRPCTWYLIYDKANRKGLEDRLLEVCAPLDGDRVGRET
WLELLRTLRERGKGPRIRDAFFDRKRFRREREALLLEVRQPAWWQGDDRYHPPACDEPAS
GLEASLRRGSFVVTAEIAPPRGSSPESIREKVGWLRGIVTAANFTDNASASARMSSLASS
KICLDAGIEPVMQLQARDRNRLALEADAIGAGGLGIRNVLCLTGDHQRFGPAPMAKPDQF
DLDSVQLLWMLRRLRDEGRCLDGREIEDPPRLFLGAAASPFGAIPAYEAIRAEKKVNAGA
QFIQTQPVFD
>A0A7C2RW33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MALLGTLRAKAEAGERTFTVEISPPVNYKTIVKTGEMVQALKDFDIAGIAVTNSTGGSFR
MNPLAVVETIRAWRPETPIVIHLTARDEGSVRSVYSRADEMNRRAVSDVLVLRGDPTPHR
SREVDAFKFSTVELVQLLREYRDAQGYAIDIFVAGHPEYPSHALAKHMAYQRRKIEAGAQ
GIIANIITDPTNYARYAEAALAHGITVPILPSVIPLTSVRRCLFLHRSLHIPVPREIVER
LEQARSTEEAARIGLEVTIEIVERLLSDGAPGVNFNLIFPHDIASVADILRAVRGHATIW
EKYKIEDPEEIEYYSQLRGRLS
>A0A1S8LGK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium felsineum DSM 794|TrEMBL
MIREYIKNNILVTDGAMGTYYSKITGDYNNFCEFANLNNPKVIFNIHKEYIDAGAKFIRT
NTFSANTLTMDISKEELRNIITEGYKIAKKAAATKDNVFVAADVGPINKFEVGKPVEYII
EEYKFVVDTFMELGADIFVFETLSSIDCLEEIFKYIKLKNKYAFILTQFAVMQDGFTREG
ISANSIVNKMNSIKNIDAYGFNCGSGPAHLYSVIKNLKLLGDTISALPNSGYPELINERM
VYVDNPDYFADKMSMIKNVGIKILGGCCGTTPRHIEKLVEKLKTNVKQVEIKAIKKEEKP
NKKREKNKFWEKLVKDEFPIVVELDPPFNIDIDKIMYAAEVCKKNNIDLVTIADSPMSKV
RVDSIMIASKIKRELGIEVMPHMCCRDKNVNAIRASLLAAHIEGIRNILAITGDPVTGID
KVNTKSVFNLNSFKLMNLISEMNKEVFKHDEINIGGALNLNVLNKKIEVSRMLKKVDNGG
TFFLTQPIFEESTIEFLANLKRDKGVKIIGGILPLVSYRNVQFINNELFGVNIPKEYVER
FKIDMSREEAETVGVDLATELIHKIKKYVDGIYMVTPFNRIEMVMKILKNIRK
>A0A3A9SLB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. X503|TrEMBL
MKVSEIYKSGKKTLSFEIFPPKKDEALKNIDATLEVLTELKPDFISVTFGAGGSSNRNKT
IDIAKKIKHEYHVEPVVHLTGLQYDKNEIDEFARVMKDEGIENVLALRGDRNPQLVEKDD
FKHASDVIKYLKEKYDFCLLGACYPECHPESESRVSELKNLKKKADSGASALLSQLFFDN
DKFFNFYDECRIADINIPIIPGVMPVINAAQIKRMITMCNASFPERFQKIINRYEDNKEA
LFDAGMSYALSQIIDLLVSDIQGIHLYTMNNPLVARRICEGIRNIV
>A0A436JSM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.002.03.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A371YX11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataeibacter melaceti|TrEMBL
MTLTSVELIPRDRETLMHDAREVSEVFPDAQMINIPDLLRFPLRSWEAAALIRPIFPRVV
PHIRAIDIPPDAPLPGAEDEGLREVLVVQGDPPSDLKHRTYPNTTESIITRYRREAPHLT
VYAAFDPYRRAPYLEMEAIARKKDAGAAGLFTQPVFDMRMLDMCMNWLHGENVFWGISPV
VGPKSRSYWETTNHVIFPPDFEPTLEANIAFARQMMDAVAQAGGNTYLMPLRVNLARYLT
PLRRG
>A0A2J0LUG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG_4_8_14_3_um_filter_43_15|TrEMBL
MIKKITDIFKEKPRTYSFEFFSPKTDAGIARLYDTVGELVKLGPDFLSVTYGAGGSTRET
TTKIVDQLQKRFDVSVLHHLTCIGHTKDELTGIISNIKQAGVKNILALRGDPPVGVKEWK
KIPGGFEYSYQLVDMIRSLHKDYFSIGAAGFPECHMNCSSYELDTKYLKLKIDSGADFAL
TQLFFDNNDYFKYIDRLKKAGIKNRVIPGILPIVNYEKLVNFCSTCGASIPDKVRAIFEP
IKDNEKATHKTGVEFAVKQCQGLLDSGAPGLHFYTLNRIDPVREIIKNIKL
>A0A2D9T5S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sandaracinus sp|TrEMBL
MKVTEHLAKAQRPPISFEIIPPKRGDHVRDILRLVDELKEHEPPFIDITSHPAEVVYEET
PDGIQRHVKRKRPGTLGVCALIQNKYKIDAVPHVLCNGFTQQETEDFLIELRYLGIDNVL
AIRGDDKGYRKPLRDGRTQNAYARDLIAQIGSMNEGKYLDEYLDAAPTEFCVGCAGYPEK
HFEAPNLETDIRRTLEKVNAGAQYVVTQMFFENRHYFDYVKACREAGITVPIIPGLKVLT
RRGHLKAIPRTFHCEIPQTLSDELEGARASDVAEIGIQWTRQQCQELLAGGAPALHFYVM
SDASAVSSVIAGLSR
>A0A1B9R594|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp. UCD-TK1|TrEMBL
MRPAPYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFFPPRDAEAESRLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAHTTLLPVAHLTAVNHSVAELRALVGAYADQGIT
NILALRGDPPGDPLGEWVAHPDGVEYAEQLVRLIDTLGDFHVGVASFPETHHRSPDIEHD
TRTLVSKLRAGAEYSITQMFFDVEHYLRLRDRVAAADPEQGLKPIIPGIMPVTSLATVRR
MVELSGSVIPPDVEERFAKAAGNGAEEDRASVRAVGIDFATEMAQRLVAEGAPCLHFCSL
NFAKATTEVLGRLGVDVDAALHVPA
>M4AE75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xiphophorus maculatus|TrEMBL
MVNQVQQVDGSWQSCRGDSSGASNSSAESSKESSRCSTPLPDADRSDRLREKMRKRMDSG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLYIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGDDWEDEEGGFNFAV
DLVKHIRSEFDEYFDICVAGYPTGHPEAESYEQDLRHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAAGITCPILPGIFPIQGYQSLRQLVKMSKLEVPEEITKIIEPIKDNDAAIRN
YGIHQAVDMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWVEDPRRPLPWAVSANPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKNEQSVFEVFTCYITAQPNRNGQKVLCLPWNDEPLAPETNFLKDELEKVNR
RGVLTINSQPNINGKPSADPVVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVDVHGHNMTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWRVIDDMFELLDATPEPLNDEAAS
Q
>A0A1X7EZE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio gilichinskyi|TrEMBL
MKIVDLIKEKKPFLSLEFFPPKDKESWPAFFEVVEKLKVLNPLFASVTYGAGGGTQSNSL
EIVKKMKQDMGIEPLAHLTCVGASPENISYFINSLREAGVENILALRGDAPADDANFDFS
KQAFKQGSDLVTYVNENHPGMGIAVAGYPEAHLESPSIKEDFKWMKYKVDEGGELIITQL
FFDNRVYFDFCDRLSQMGINVPVVPGVLPIMSLKSAKFILSLCGAAIPGKYLSALEKAHA
EGGDDAVYRLGIDYATKQAQGLLDGGAPGVHLYTLNRAKACLEIGQALKF
>A0A429TQ00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC07149|TrEMBL
MGDHNDNATDRMLMAGAKGGVLLFGITPPRLSTAPERIREITAATLARLNFLDVDGLALY
DIDDESDRNPAERPFPYLPTIDPATYHAEYLGEWTRPAVIYRCVGKYTAAELRTWMQTAD
TGRVLSVFVGASSKDKAVRTRLSQAQTLRDGVRPDLLLGGVAITERPEEHLRLLAKQEAG
CAYFISQVVYNADAVKSMVSDYYYACRERQLEPKPVVFTLSVCGSVKTLTFLKWLGVDIP
RWLENSLRHADDTLVESYQHCLANARDLMSFCRKLGMPFGFLVESVSIRKVEIEASVALA
AELSGLLGRGQPSA
>A0A522WK42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MNFKEKIKTGKFLLTSEVGPPKGVEAAHLLEDAELVRGRVDAINVTDLQSSVMRLGSLAV
SIRLKEKGLEPVYQLTCRDRNRLALQSDLLSAANFGIENVLALTGDHPKLGDHPQAKPVF
DLDSVQLIQAIRGLEQGVDMAGKKLEGALPKFCIGAVVNPGAEPLEPQIMKMEKKIEAGA
EFFQTQAVYDIKTFENFLSKIKHLKTTILAGIVLLKSAGMAKYMNENVAGIFVPDNLIKE
MQETKDKQQKSIEIAARLIKELSPMCQGVHIMPIGWDKLVPKVLDASGL
>A0A523BG37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Korarchaeota archaeon|TrEMBL
MISLELNPPSRPSLDEIYEKIRRYNSFDAFIITELAMRREEDRWMDTMYTAIKLKEATGK
RIIPVMTSRESTKRGILSRILMAIHGGIDELVIVRGDQSPYGGAFGMTTVEIIRTIRSLC
ERFSKRVTVYVAANPTRDLEGEIVRAAEKLSSGADAVITQPTLDTNLLRKFIAGLRERGF
DNPVIGSIMILNSRNSAEMMERRCGIRFPEWFKEELERGNWRDSLLTSIREIADICDGVH
ISPIAEQDFSVLLAEEARKILRDRDEQLPIFLP
>A0A4Q3V6S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MDRDEDLRPQMSPARLTVEAIVAYPKRKDAGVFIQIGPTVFGRPTLFGDPSTVRLAVVPK
PSHRRKAGDRLRQRERPEDNRQKPAQNVQIRRVLPNIPATTTPSSPPPLILTEVSFLDAL
RGGVLVGDGANGTLLQKRGFARLPYDLANLLAPDMVRETHAAYFEAGSDFVETNTYSASR
LRLPEDFDAREVNLAGARLAREAAPEGKWVLGAIGPAGKTMEPIGSLTEAEVRASVSEQA
AALAEGGVDGFFLETFTDVCELRAAVEAIKSVSDLPVLVSKAYIEDGEMLAEGLPVRCTK
QMDEMGVAAVGANCIVGPQRMLDLVRQIAEGTDLPIIAFPTPGLPQLVKGQVVYDTDPDY
FARASLRLVEEGATVIGGCCGTTPEHIARLRELLDARPPKAKARVRATRESRLPTDLPQS
EPSELAQKLKRGKFVTAIEMDVPRGLNLEKLVAGARALKIAGADCINVSDGARARLRMNP
AAVSTLIQQRVGIEVTMHLSCRDRNLLAIQADLLGWHALGLRNILAVTGDPANIGDYPSA
TSVFDIDSIGLCRILSRFNEGIDMAGYSVGLRCGFTVACAYNPLALDPELELDRLRRKVD
AGAQVVYTQPVFEGSIAEACAETCQKLGLPVLVGVLPLRSQRHAEFMHNEVPGIEIPRWL
RERIAATTDDASALEVGVDEARKLATTIRGCAQGLYLMPPFGSASIAERVMAA
>A0A853GFG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MSQQQKVISLEFFPPRDIAAQEKLVRSAKQLLALHPSYVSVTFGAGGSTRSGTTETVRLL
KNLGCDTAPHLSCVGSSKAFLAETLDAYQELGIKRIVALRGDLPSGMGGDAGELHYASDL
VGFIREHSGDWFHIEVAAYPEVHPQSDSAATDMNHFVTKVQAGANSAITQYFFNADAYFD
FVSRAQHQGVNIPIVPGIMPITNGSQLLRFSNMCGAEVPRWVRQRLSDFGDDKASIRDFG
IDFVGDLSQRLLDGGAPGLHLYTLNNADVTMALWKQLRLN
>A0A7Y7HSL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. SG902|TrEMBL
MDNPNFSIEFFPPKTAEGAEKLRATRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILA
AGEDAAPHLSCVGGTRESIREILTEFKSHNIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGDWFHIEVAAYPEVHPQAKSPQDDLLAFERKVKAGANAAITQYFYNADAYFNFVE
QTQKLGINVPIVPGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VAALGERLLKGGAPGLHFYSMNQAAATTALWQRLI
>A0A661AZV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
GVAFNQNAHSIERELERLERKVESGANFVQTQPIFSTDGLERLANFLKNKKIPIIVSILP
LTSGRNAEFLHNEIPGIKIPKKIRDIMKNAGNSKKAREEGIAIARDMLASAKELAQGACI
MPQLGKFDMVEKILY
>A0A661BHK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MSINSITEIVSERILICDGAMGTFLYDIGAPSGHCYDELSISKPEMISRVHREYIAAGAD
IITTNTFGANRYILDKYYDLGDKTRDINISAVRIARACAKHSDREIFVAGDIGPVTRPLE
TAEILTESQIEQIFYEQISMLTEAGVDIIIFETFADLSELLIAINTAKKCALNIPIWASM
SFVDGKTLMGDDPERVGKALSETDILIVGANCGRGPKEILDAAKQLGKVFPRFVSAMPNA
GQPTFVDGRFFYPATSEYFAEFAKKSYLAGINIVGGCCGSNPEHIKAMSSALNKKKPRKR
KMIPGAKIPEPTVKVRKYPRTPTSFEKKIKSDFVLTMEIDPPRGTEVGNLVYRARVFKEL
GGDAINIADLPMARMKMSALGLAAAIRIRTGIDIILHFTARDRNLIAMQSDLLSAYALGV
DNILALRGDPPAVGDYPFATGVFDISTYGLVNLISSFNDGFDLLGNPLDSPTSFFIGVAF
NQNAQVFERELERLEKKLESGAHFVQTQPIFSADGLEKLIKFLEGREIPVIASILPLLSA
RHAEFLHNEIPGIRVPQKIRHILSKKSNKKSARMSGISIARDMLKVARELAQGACIMPQT
GKIDIIEKILY
>A0A846N0X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizomicrobium palustre|TrEMBL
MSLKDIAQRDRPIRVSFEFFPPKTAEMEEQLWTSIKRLAPLSPSFVSVTYGAGGSTRDRT
HATVKRLVQETGLKTAAHLTCVAAPKSEVNEVIREYWHAGVRDIVALRGDMPVAGTPYAH
HPEGYASTPELITGIRSIADFEVSVSCYPERHPESPSLEHDLDLLKQKVEAGATRAIAQF
CFSNETLARFRDRADRWGINVPILPGLMPTTNFKGIARMAGRCGASVPTWLAGLYEGLDN
DPESRRIVASAVMAEQVSDLYAKGFDQFHFYTLNQADLTYATCRILGLTPKENP
>A0A7C3UZ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MSNLRIKEKYKSENTGFSLEFFPPKEIGQEEKFKETMRKYIDLKPLFASITYGAGGTTQN
KTFEIVKFVNSLKAFAVMPHLTCIGATKDSINSLIREYDELGVFNILALRGDPPKDDKNF
DINKGEFKHAVDLVKYVREYFDHFSIGVAFYPECHSQAKSFEEDFEYCLEKMKFADFAIS
QMFFDNSYFLRYRDLVLKRGINITLVPGIIPIANFEKIKEFAKFCRVDIPKKLEDSMAKS
SSHEDMKKIGIEYATEQCSELIKEGVKFFHFYTLNQFELCSNVIKNFW
>A0A6N7URA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Suipraeoptans intestinalis|TrEMBL
MKIKDILEKKGAHISFEVFPPKTESGKESVLQAVKELITLQPDFISVTYGAGGGTSSQTA
GIAAAISKAGVTSLAHLTCVSSTREQVHQVIDRLKEEGIENILALRGDIPDSGQFPLPNH
YRYASELIEDIRTRGDFCIGAACYPEGHVETPHKKDDIRHLKEKVDCGVDFLTTQMFFDN
HILYNFLYRIREKGITVPVIPGIMPVTNAKQMQRICQLSGTVLPARFLAILDRFGENSAA
MEQAGIAYATDQIIDLLANGIRQVHIYTMNKPEIGRKILENISQIIRV
>A0A6B0R013|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos mutus|TrEMBL
MKRRMDSGDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETS
SMVIASTAVNYCGLETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPIGDQWEEE
EGGFNYATDLVKHIRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEKVAAGADFIITQ
LFFEAETFFRFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIK
DNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLP
WALSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYL
KSKSPKEELLKMWGEELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMK
EELLRVNRRGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQV
LKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKWGKL
YEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>A0A7Y5ZHG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia sp. C5G2|TrEMBL
MSCTDARYSFELYPPRTERAAAALPATIDRLAAVHPDFISVTYGAGGSSRTASLDVLRYI
IERTDVSAMAHLTCVGSSHEEAHRLIREFLDAGIRRFLAVRGDPPADLPAGEDGIGDIRT
TAELVQLIHRVQAERAPYGELSVPGLPAQAVLQHREHVQIAVAAFPNGHPSSHSISQDID
ALLAKQAAGANLGITQLFFHAEDYLHFAQRAAEAGVTFPILPGIMPVTSPARLKRMLELS
GEDLPSDLAIELEVEPTDEGRREIGIDWAARLGRRLLDGGAPGLHLYTFNQHEAVLSMLD
RIGVLPEGGAEHTHTPKKPATEKETA
>A0A7V2N127|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MNCNKLEIIFTVIPPPLEWDISKIERKAFEVANITKILDIDFISLPEVIEERSRGQRIIP
YKMKFDNAEFGKMIKNFDNSVEIIVNKISVIMEKEEFETWIKENSKSFNYLLIVGGESSK
IKYPGYHPIPATLIAKNYFKNVYGITIFHRKDEPKKLLEKTKAGMKAFISQIVFELENAK
KVIYEYFKLCEEENIKTSKIYISFAPVSQRKDLEFLKWLGVYVPKEIENYLLEDEKKLEK
RSIEIIESLFQELCFLNIENIGINVEHVMYNNLQVAAYAVHRIKETWKWRN
>A0A6L4YBH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MHFQELLDSKKFLVISELQPPKGTNLTEFYDYAEKMRGRIDAINVPDLQSAVMRLGSLSA
SYLLKEKGFTPICNMTCRDRNRLALQSDLLNISVLGIENIVVSRGEDPSLGDHPDAKPVF
DLTSLEFISAVRDLQKGYDMAKSDLHGTPKFCVGSTVNSSAQRGALDLEIKKMEEEIRAG
VDFFLTTSVFELDIFENFIRKIEYLKVPIIAGIMILKSVGMARFMNKHVEDVFVPEVLIE
KLMKSADKPKTSVEIASELINGLKPLCQGVHLIPFGWEDKVPSIIEKAGLY
>A0A5C8W376|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. WL119|TrEMBL
MPNANRHRASRDGYHPIRVSIEFFPPKTEEMEKILWSSIERLAPLGPKFVSVTYGAGGST
RERTHNTVARMVTETGLKPAAHLTCVDATRDEIDAVVQSYWDAGVRHIVALRGDPAEGVG
HAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFENDVYLRYVDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
DGLEGDVETRRLVAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKV
ATAKAA
>A0A260M9S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 05-2254-4|TrEMBL
MSEESVRGRSSRGFVTRTPSIVDRLRTEPEARIPFSVEFSPPRDAAAEARLWRAVREFEQ
LQPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRG
ITNILVLRGDPPGDPLGDWEKHPDGVEYAEELVRLVRDLGDFHVGVASFPEGHHRAADLE
QDTRCLVGKLRAGAEYSITQMFFDVDDYLRLRDRVSAFDAEQGAKPIIPEIMPITSLRSV
RRMLELSGTTLPSHLDEKFTRAAGSGPEEDRAAVREVGIELATNIGERLISEGAPGLHFI
TLNFARATREVLSNLGLAAARV
>A0A522YAE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MNFKEKLYSGKFLVTSEVGPPKGIETSLILEEAQLVRGRVDGINVTDLQSSVMRLGSLAV
SSILKQNGFEPIYQLTCRDRNRLALQSDILSAAALGIENLLILTGDHPTLGDHPEAKPVF
DLDSVQLLEAVRKLQSGVDINGNKLEGKLPKFCVGAAVNPGADPIEPQIMKMEKKLQAGA
EFFQTQAVYDVKSFESFLGKVKHLNAKIMAGIVLLKSEKMARYMNKNVPGIFVPDDIIKE
MEDSKDKSRACVEIAARLIRELKPMCQGVHIMPIGWNKYVPKVLDEAGL
>W6MCF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Competibacter denitrificans Run_A_D11|TrEMBL
MDSQKHYPKQISCEFFPPNTDEGMAKLAAARKALMPISPAFFSVTYGAGGSTRERTLQAI
QGIRANSDVDAAPHLTCVASTRAGIREILTTYRKLDIRRLVALRGDLPSGMSEFGEFRYA
NELVEFIRAETGDHFHIEVAAYPEFHPQARTTERDLLNFKRKVDAGANSAITQYFYNPES
YFRFVDDCEKLGLDLPIVPGIMPITNFSQLARFSDNCGAEIPRWIRKRLESYGDDLSAIR
AYGLDVVTDLCRRLLAAGAPGLHFYTMNRAGPTLAICERLALIRG
>G9NF79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypocrea atroviridis (strain ATCC 20476 / IMI 206040)|TrEMBL
MMDKITDKIAALPADGEYFSLEFFPPKTQMGFSNLRVRLQRMERALRPLFVNVTWGAGGS
TAQKSIELAELCQRELGLTTCLHLTCTNMSQAMVDQALQDARALGIRNILALRGDPPRAE
YRDADEPTGSEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPYL
VDKVQAGADFIMTQLFFDIKAYEKFETTLRDDPSGAFKTIPILPGLMPIQSYAMIKRTAK
LSHAEMPEEIMARLNAVKGDDEKVKMVGVDILSELIEQIREIKSRTPGPRGFHFYTLNLE
KSISFILERTKLIPDVPEDEEAVVDEPVPAAVTGQRSIPRISVNGNVPLRQSRSHSRTAR
RQSSVGSDPHNRVIVGRAAAHPEWEASSTEAGLPAESINTRANTLAISEGEGALGREATW
DDFPNGRFGDARSPAYGEIDGYGVSIHMSVTQAVSLWGHPKTASDINDIFVRHIRGEISA
IPWSEEDLLPESNIIKSSLEAMNKKGWWTVASQPAVNDLPSNHGTFGWGPASGFVFQKSF
VEFFIPSADWKILYDKLTSEEHEEVVCFYASNANGDFVSSDSTGGTSRAAVSASTNAVTW
GVFPGKEIVTPTIIEEVSFRAWCEEAFDIWAEWAKVYGRGSDSEKLLNEIGQDRWLVNII
HHDYVDTEALWRLLTN
>A0A356EB24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurellaceae bacterium|TrEMBL
MSYAKEIDTLNQHVADLDGKINVSFEFFPPKNEKMEETLWASIHPLKTLTPKFVSVTYGA
NSGERDRTHSIVKSIKQVTGLEAAPHLTGIDATPEQLVDIAKDYWQSGIRHIVALRGDEP
QGYAKKSFYASDLVALLRGVADFDISVAAYPEGHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVESYLRFRDRCASIGIEAEIVPGILPVTNFKQLLRMSSITNVKIPNWLAKMYEGL
NEDQTTRNLVAASVAIDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A1E7HSK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium S5133MH16|TrEMBL
MHLKSKFESEEFVVLAEMEPPKGVDVSTMVTSAMRVKGEVDAFVVPEMSNAVMRMSSLGG
AMILQRKGMETVIQVNCRDRNRIALQADLLAAYGCGITNVMAVTGEDPSFGDHYQARSVY
DIDLLELLRAARGLQEGKDMAGIDLSGSPEFLVGSTVNAGAKGKSYELEIEEMNKKIEAG
AQFFISPPLFDLSAIQPFMKRVDQKKTKIIPTVLLLKSLGMARYIIRNMDYVYIPDLLID
RIKKAPDKVRECTLIASEMVTTLKEEGFSGVNIATLGWEHKLPQIIEKI
>A0A4R2CQL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2500|TrEMBL
MATGLPSTRPGSRPTIRELLSTGQPSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVSHSRDELRSVIGAYAGSGVRNILALR
GDPKGGPSQPWVAHPEGLNHAVELVELVRSLGDFCVGVAAFPDKHPEAADLEADAQVLAV
KAAAGADYAITQMFFGADDYFRLIDRAAALGCDIPVLPGVMPVTNIKQIERMAELTGMAL
PKPVTDRLNAVAEDPAAVRAVGIEIATELSDKLLAGGAPGIHFITLNRSTATRQVFRNLQ
SAVV
>A0A522PNM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKIAEILAARRPAFSFEFFPPRSDEAMAALLETVSTLRSLGPAFVSVTYGAGGSTRARTI
EITKTIKRELDIEAMAHLTCVGATAEELRSTLGDFRSAGIENVLALRGDPPQGESAFTAV
EGGLAHGADLVRLAREGEAFCVGGACYPEKHIEAPDAAGDLRHLRHKVEAGAQFLITQIF
FDNQRYFSFVERARRAGIDVPIIPGIMPITNVAQIERFTRMCGATIPSRLMAELEARREE
PEAVIDLGVAYATLQCVDLLTRGVPAIHFYTLNKSPATRAVVSALSAARPWEPAKGRRYV
ENADSIIESALSLPSSL
>A0A317PX35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mangrovibacter plantisponsor|TrEMBL
MSFFHANQRDALNQSLAEVQGHINVSFEFFPPRTSEMEQTLWNSIDRLSSLRPKFVSVTY
GANSGERDRTHSIIKDIKERTGLVAAPHLTCIDATRDELKSIAQDYWDNGIRQIVALRGD
LPPGSGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVENYLRFRDRCAAAGIDVEIVPGILPVSNYKQLQKFATMTNVRVPQWMATMFD
GLDDDPETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAI
>A0A2H4VUT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Lz4W|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETADHFHIEVAAYPEMHPQARNFEDDINNFVRKAHAGADSAITQYFFNADSYFR
FVERVRAAGVTIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIQSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A4Q8U3N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. KUL42|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEKTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVSAVPHLTCVDASREELKQIAKDYWDSGIRRIVALRGDLP
PGVDKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIS
QFFFDTSVFLRFRDRAAAAGVDLDLVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DDDDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRGNS
>A0A0B8PZX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. JCM 19236|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLVAAPHLTCIDASRDELINIADDYWNNGIKSIVALRGD
IPPGGGKPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRSVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMSQQFE
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQTA
>A0A6S6YID2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter pestifer|TrEMBL
MDEHPPLMHSSRPTFPGNITDAYSLEVSVKDIAALTAVAPRILPGSTISIPYLPGQDNDA
RLATAQAVRGLGLVPMPHLSARRIASLAELDSFVKRAVAEAGVERCFVIAGDPSTPVGPF
SDSSSLIETGVFERWGIQVVGVGGHPEGHPVMSTADRWDVLERKCDSIGRRGMTPLIVTQ
FGFNADIVLMWLKTLRERGIEHPVRVGVPGPAGIAVLARYASLCGVSACASMWSKYGISL
GKLFGTAGPDVFVDRLAAGLTEEHGKVSLHFFPFGGIAQSVRWIEQYRSRAEQLRYASAS
LS
>A0A845M0A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritimibacter harenae|TrEMBL
MTGLSDDVSISFELFPPKTDTGVARLRESVAQLSAADPNYFSVTYGAGGTTRDRTARMVD
MVSNQTGRPVAHHLTCVGASRAEIDRQAEALWAKGLRRIVALRGDLPDGETVPADGYRDA
AELVGALRSVGDFDVSVAAYPEVHPEASSAEGDLDHLKRKLDNGAARAITQYTFDTDTIL
RFIDRARAAGIEAPIVPGIMPVANFASLRRFSEGCGASIPDWMFQMFDGLDEAPDTRAMV
ATCAAAEQCRRLMEAGLTEFHFYTLNQPKVSLAVCRALGLTPDIPAETAA
>A0A497NAA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MSKSSSSKFMKTMRACPKRVLNGPCGGMRSDGTCEVLEFKCVFYENYPSELLLDDGFKIK
PRIKHREYFTKLLSRTYERITWIAEIPPKAGITKKLHILRETTEDALSIPDNPFGRTHIE
PTAFAAYLGNLTKSEIVVHLTCRDLNRLALKSRILGLDLIGVKHVLALTGDHISPYEGNR
LMGVFDLDSMRLIYMIRLLSDYGLDERGRRITDKVTLHVGGGLNPYLPLEIELSRILRKL
NSGSEFFISQIIFDESYLIPLLKELRREGINVPIFAGFLLQDYDKIVSFTRTSALPLDDV
PKNLDKLIERYLESLRKLRREYKVIGAYVSTLGKLEYLRTWSEYITGSF
>A0A842N8X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MRNKRPAYSDLMKEIREGKFVLTGELEPEKTTGLEEILVSARAMKPYVIAANVTDNPLAM
AFMNSLVPSYVVQRDVGLETVYQMVIRDRNRLALLSDVLAAAHLGIKNILAISGDHTVLG
DHKGALPVYDLDSAQFVYMLSKLIDEGVDLEGNEIHGKVPINVGIAANPNANPLEPEILK
VERKTKIGADFIQTQTMFDIDLTKEFLKETERLNCPTLIGVFPLKSFGIADFFDKYIPGV
SVPKDLLESMRKCKEEPDKEKRKMLYDEVNMEFFAPFIREIRKTTKAAGVHVMAVLYERI
LEPLVAETM
>A0A842QRT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MFYESLNVDCPITYEVVPPRGYNIDSLGYIEAVEKHLSGVTITDNPMATMRISPIVYGSY
IKEHFNIPIIPNLSCRDRNLLALQSELLGAHMLGFRDVFLITGDSPKSNGGFKGVWEVKS
GDLCRIVKGLNNGSAEDKGNIRKIQTPTDFNVGGAIVLSRPNELDYFRSKLACGFDFFIT
QITYEAQPLIDFIESISKWGESPIQVGLAPVSTSKRLRAISRMSGVDISDETKKRLTNSN
DFKCAMVSELSELADSLRSELDYPIGFHIMPIGSDELGTRLVKELKK
>A0A2N1K476|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. SN10|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAILNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDEAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7C0XG08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MENFLEEILLNKDYILFDGAMGTYLYSRGVPIGSSTMEINLSNPSLIRKIHEEYINAGVD
IIKTNTWSANYSKLSQYNLENKVYEINFRAAEIANEASKGRVLIAASIGPLSKTVEPLGG
MKRNIAYQIFREQLIPLLDAGVDLILLETFQNLDELLLALKVAKEMSNIPVIAQMTFPNG
FSTIYGYSVMDFAKTMENEEVFAIGVNCGLGPWHLLKSIEILRSYTSHHISAQPNAGVPK
FLGDTLYYPTDPLHFSEYGIHYYRLGVRILGGCCGTTPKHIAELYSKLSMKRPKEMVIPK
LKPEVEIKKWTPTLLQSSLKKFFTILVEVDPPRRLSLSKIFRALMKLRAAGVDAINIGDN
PLAKPRINSIVFAHLVMENLGLETVAHFRCRDKNLLAIISDLKSAHILGVRNIVVLTGDP
ISIGEYPHVTPVMDIGATGVIKLMSMMNRGQMPDGSLLGESTSFYIGSVVNPNAKNLMKE
IRLLKKKVKFGARYVLTQPIFQTEKLKRFIKKADLNIHYIAGIILLKNEKHAMFLNDEVP
GIEIPDEIITKLEEGYSGMEIAKEVLSKLLGIAQGAYIIPPARNISLAGELVEYVKSITK
RL
>A0A843CIG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MKLSELAKHQRVVTAEVIPDRVVPAHLPLLQHRVDAIGIPALRSGESDPSYPTGFRVSPQ
TRSIASSVIVKRSGFDAIPSLTCRDFRRSDLELLPKLFEKGLENFLVVFGDPFPNCKLRD
YDFKKAEDLLRAVKSAFQGRTGPSLGAVTNQYALDWEQEISRTINKADAGADYVVTNSAF
DDYFVLEYIDALRSHGLKIPVFVQLSIPHGLNNLLFVSKRFGIPVPERVKQTVSRNPLGG
GVNVIAQAYEGLKREVNGIHFSYLYRSHNPIPTYTHLLDAIQTDGQLIVALKATLKN
>Q2STU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKAVCERLGL
>A0A537F3S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MRLSDQARHHNLVTVELIPDRVVPNDLALLRGRVDAITVPALRNGHDDPSYPKSFSITPQ
RRSLASASIINRAGITAVPSLTCRDCSRSDLAAISNQVEQGLGNVLIVYGDPYPEPRPGT
YEFTKTSELIREISSLNDGNDPCIGAVTNQHADKRESEISRTISRVEAGADFIVTNVAFD
SESVLEHRDSLLEAGLNVPLFVQVSIPLSLDNLLFVSQKFDIPVPAHVRKKLLDDPTGGS
LAVAAEAYEALRGEADGVHFSYLFRQRNPIPTYRHLLETIGIARPTLAPIATSPVNTYPV
A
>A0A2Z3ULZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium sp. 'caverna'|TrEMBL
MALGRPSILPDRVPTVRELLAAGGRSFSFEFFPPKTDEGERQLWRAIRELESLHPTFVSV
TYGAGGGTRDRTVDLVERLAHETTLTPVAHFTAVNHSVRELRHLIGRFAGAGVRNILAVR
GDPPGDPMGEWVPHPEGVLYADDLVRLIRQSGDFCVGVAAFPYKHPRSGTVEADTEHFVR
KCRAGADYAITQMFFEADDYLRLRDRVAAKGCDTPIIPGIMPVTQMSTIARSEQLSGAPF
PPRLTARFEAVADDPAAVRELGIEHAAELCQTLLDEGAPGIHFITFNRSSATREVFQALD
FAPKAVSLAGR
>A0A2A5SWV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus cremoris subsp. tructae|TrEMBL
MKTLDSLRALSPDFISVTCSNNNYENIADTTIKFADYVNNTLNIPAVAHLPAAYLDKTQV
IEILERLREKQIMKVLALRGDISDEATKKDFKYASDLVKFIKDYDSSFEVLGACYPDVHP
ESINRISDFHYLKEKVDSGADKLITQLFFDNNSFYDFQERCAIAEINVPILAGIMPVINR
NQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAGIAYAIDQIVDLVTEDVAGIHLYTM
NNSETARSIHSSISSLFKINT
>A0A2S6SD03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha5_Bin11|TrEMBL
MKNISLLSKKLQEGVFVYTAETTPPDASDMNVLINRTIFLKGVADAINVTDSPGAKVHMS
ALTASIILVQNDIEPILQLTVRDRNRIALQGDLVGASALGIHNILCLSGDNPKNGDQPES
VAVNDINSLTLVKTANLMRNAEQYPSGRKIDPPPKFFIGGAEVPTAGLPDPKKILQKIDA
GVDFFQTQYVFEDSILKEYMNVLEGEGILEKTHFIIGIGPFASAKSAKWMNDNLFGVSVP
NKIIKRLEQSQDQKKESKNICIELIQSFREIRGVKGVHLMGHNKEEVIAEIIKESKMQ
>A0A1C3YLI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WEAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPSADRP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKAIQDIAELFVSYLNNKIESLPWSESPLTTEADEIRDDLIE
LNKRGLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPV
ANGAVDTEPIANGTAVTAAAN
>A0A1H8JG22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus alcaliphilus|TrEMBL
MSRPAPKISFEFFPPKTLDASFRLWETARALAPLRPDFVSVTYGAGGTTRKLTHEAVTTI
NRHYGVNVAAHLTCVEATRAETLEIVGSYADAGIREIVALRGDAPRGQDRFTPHPDGFAS
SVELIEAIAARGDLTIRVGAYPEPHPDSNGADADVAWLKRKLDAGATSAMTQFFFEPETF
FRFRDKCAAAGIEAPIIPGILPIQGWAGARRFAAACGTSVPGRIEAAFDKAVAEGPEAER
RLATDLCIDLCGKLIEGGVDRLHFYTLNRPEMTLDVCAALGIRPEGNGLEAVA
>A0A1X4MHD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter concisus|TrEMBL
MLKDKIINNESGIVLYGLTPPKAEFDEAKLKEIAAKWDKRITDVQADGLVLYEIQDESSR
IKSERTFEFSDTLSPEIYYSKYLNLKTPSIFYRVANKYNESEFRANLAKSSSDINVFVGV
ASGKVEPKMSLERAYEIARDEFKELVVGGVCIAERHAKKGDEEQRMSQKAKMGAKFFISQ
AVFDIDLAKNLLESVAKSGLNLPIILTFTTCGTPKTLEFIKWLGISVDEKSEKRMLQSNN
FLATASQICLENFAELYEFAKKLGINVGVNIESVMAKRAEIEASLELTHKIREVF
>A0A223HK53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. CT06|TrEMBL
MKVIDLIRNSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQKPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNDKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A261QN97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sodalis-like symbiont of Philaenus spumarius|TrEMBL
EMEKTLWQSIDRLSELKPTFVSVTYGANSGERERTHSIIKEIKERTGLDAAPHLTCIDAT
PPELQAIAQDYWRSGIRRIVALRGDLPPGSGRPAMYGADLVVLLKKVGDFDISVAAYPEM
HSEAKSAQSDLINLKRKVDAGASRAITQFFFDLESYLRFRDRCVAAGIDTEIVPGILPVS
NFSQLQRFAAVTNVKVPNWMTTMFDGLDHDLETRKMVGASIAMDMVKILSREGVKDFHFY
TLNRAELTYAICHTLGVRPEIKIAPAAHRDALSRVPMSRVSDVRA
>A0A1E7I1T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp. S3730MH75|TrEMBL
MNVASNIKGSSQFFSFEFFPPKNMDAWDTFMGKAERLTALNPLFASVTYGAGGSSHDNSL
DVCKAIKDGMGVDILAHLTCVGASEESINDYVRKLREVGVSDILALGGDGKKDEGQSESR
FFHAVDLVEYVEDKYSDVGIAVAGYPGGHPESPTLAKDIKFHCAKLSKGSDFTITQLFFD
NRQYFDYVDRLVEYGFEQPVIPGVLPIQSLGSLRRIMSLCGASIPGDLYCGVEKAFEDGG
DEAVMEYGFTFARNQIAGLLNGGAPGVHIYTLNRAAMCERLIGDLKSDGYFI
>G7M5N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. DL-VIII|TrEMBL
MIKDYLQNNILIFDGAMGTYYSELTGNDISYCEFANLDDGDTIKKIHKEYINAGAKLIRT
NTFSANTHDLGVSYETLKNIIKCGIDIAKEVTRNTSVFIGASIGPIKEDNIDESQEDILK
EYKYIVDCFLDNNINIFVFETFSNYNYLKEISEYIKGKDSKSFILTQFAVKPDGFTRDGI
SASKLIKKVKEIKTIDSYGFNCGSGPTHVAEFIRTIDIENDIVSAIPNAGYPEIIHERTV
YPNNPVYFANKVNAMTTLGVSIIGGCCGTNPNYIKELVSLIKNNSNEINSYSKKEEIKEY
KEKTENAFKNKLDKNEFTIAIELSAPINTDISKLMAGAKICKENNIDLVTIPDSPMSKVR
ADPTIIASKIKREIGIEVMPHICCRDRNTNAIRSSLIGSHIENIRNILAITGDPISDANK
IETKSVFNLNSFRLMKLINDMNEDLFKEDNIYIGGALNLNVLNKDVEFNRMLKKIDNGAK
FFLTQPIYEDDAIEFLSKIKAKTNVKILAGLLPIVSYRNAVFLNNELPGVKIPERYMKMF
SENMSKEEAQEIGVKIAVEIGNKLKGVSDGLYFITPFNRVNMLIDIVKQLQLS
>A0A7C7DMS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MYVATLRHKLANNLFVITAETNPPRGPDPSRVLSRIAEISSVVDAVNIADSPMAKMRMSP
VALAHIVQEELGVETIVHFTCRDRNSIALQSDLLGAAALGIRNFLAITGDRPAQSGNHPD
NPCPRAVFDVDAAGLVRLAETLNNGYDASGNKLSGVPDFFVGVVANPSAQDLDREVERLE
HKVRSGAKFVQTQPVYDLRTLQRFREKTAYLEVPVLYGILPLKSYEIAVYLHEKVPGVVI
PDTVRERVRLGGRRAGVELARELFAEIRDQVAGVHIFPMGDTDIVLEVTNGLEVRQALAT
>A0A8G1YKK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus pasteuri|TrEMBL
MSQFLKKLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVERIHRSYIEAGADVIQT
NTYGANFEKLKVFGLEHKVKEIHKAAVQIAKKAANNNTFILGTVGGFRGVKQDELSLSTI
QYHTENQIDTLVDEGVDALLFETYYDLEELTGIIVSTKRKYDIPIVAQLTASNTNYLVDG
TPINDALKHLVECGADIVGLNCHHGPHHMQRSFSHIELPNNAFLSCYPNASLLDIKNSEF
KYSDNAQYFGDIAQELIHEGVRLIGGCCGTTPEHINYIKTSVSNLKPVNHKNVIPIHKKV
NREKDISFKQSLTSKVKQGPTVIVELDTPKHLDTEQFFNNIGKLDDADIDAVTLADNSLA
TVRVSNIAAASIIKQRFNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEATKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITTHKEAIL
>A0A3F3A6E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum (strain 657 / Type Ba4)|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIHDTLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKNIIGE
YNYAFELIEKIKANNKFGVSGACYPEGHIECESLEQDIRELKRKVDAGAEHLISQLFFDN
NVFYEFLNKAQQKNINVPIQAGIMPVVNKKQIERIVEISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A8B9WYP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos mutus grunniens|TrEMBL
MDRPKPKVFPVGHCCPSLGMRASEAGSGRLSVPPSISRNSAMVNEPRGNGSPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQAEPPPPASCFLPSEHPVQEAVCLALLPAAQGL
>A0A1V6FDH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium ADurb.Bin082|TrEMBL
MVQQTRQLNMSFEGDCRLASAMRSGQFCLLLEMNSPPSNQPLDSYMAAATPVFKQVGMLP
GVHGIAVTDRWPTVQRQDPVDFAAQAMKGSGKPVLMTLSGRGTDLARAKTLLAEARAKGI
RCFLAVTGDWLGKNGAEDVPTTYLDSVTTTVTACQFGSDAWVGAAVNPYKYTCEGVFLQY
AKLQRKITHGADFLVAQVGWDMKKAQELQWFLQMRELYRPTLARVVLMNQDDALKLGEGF
WPGVPMPIPLGALIMREAAGTADQFLEAQLSRTALQIVGFRLLGYSGVQVSGVRTPNLLA
QLVDRVHDCTAECPDYDAWLEAWRQRHGDISFGPGASDLCPDPPYYLFADLQQPGRRDFD
PELAQVSFNTIAPPTLGDRWTRWLHRPTRPRLIREAVRRLTFRSEVDEAAADLCQGLLNR
SCPKGLVYGACGGASTDGRCEDGNLECFFHRVIRLASAANDLEALENGEVAP
>A0A8I1BXE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. AP02|TrEMBL
MSTHNFSIEFFPPKTAEGAEKLRATRARLAALEPKYFSVTFGAGGSTQQGTRDTVLEIIG
EGHQAAPHLSCIGSSRTSLRAILDDYRAHGIKRLVALRGDLPSGYGAMDQASSEFRHANE
LVEFVRAETGDWFHIEVAAYPEMHPQARSPQDDVQNFARKVKAGANAAITQYFYNADAYF
RFVDEAARLGATVPVIAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTESIRAF
GQDVVTQLCERLLAGGAPGLHFYSLNQAVPTEAIWRQLVK
>A0A7I8MSZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis associated proteobacterium Delta 3|TrEMBL
MTAKTPSRLEKVLAAGHLAVTSECGPPRGSDPEVIAKKAEMIKDYVDAVNITDNQTSMTR
MCSLAACIRLKLMGLDPVLQMVTRDRNRIALQSDILGAASFDIHNVLCLSGDHQSFGDCA
NGQNVHDIDSMQLLQTVRLMRDDGKFLGGDDIKRPPQMFVGAAANPFADPFEIRVPRLAK
KVSAGAEFIQTQCIYNLDKFELWMKMMRDRGLHEKVYILAGLTPMKSAGMARYMKKRVPG
MDVPDEVVDRMAAVPKEQQAQEGIDICVEAIERLKEVEGVAGFHVMAIEWEEKVPEIVER
TGLHPRPAVD
>E3QQT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)|TrEMBL
MHIKAMLEETRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREHEK
WEATEDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDGDNFVRWVGKVRERGITVPIIPGIMPIATYSSFLRRAKHMNCKVPDAWMAAL
EPIKNDDVAVREVGKGLVADMCRKIVAAGIHHLHFYTMNLAQATRMVLEELNWMPTSDRP
VKHALPWKQSLAHGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSISDIATIFVRYLETELDSLPWSEAPLTSEADHIREELIG
LNKRGLLTINSQPAVDGVKSNHPVHGWGPANGYVYQKAYLELLVHPDVYAEIVSRIEKNP
DMTYYATTKNGTLKYNATNDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGIDW
AHCFDAGTPSRVLIERIMNEWYLINIVNNDFHQKTALFDLLEGLEVKEYTDIPLEPQTNG
AGKEQAAVANGNSAPITAN
>A0A5C7NXQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MTSPVPQFSAEIFPSETVAGLARLEQTVRTLHALGPDFVSVTYGAGGSTRGASQVALDRL
RAAGIAAVPHLSALGASRQDMRSQLDTCRDAGVRRLVVLRGDAPSGLRAHGEFTFATDLV
RFIREETAGRFHIDVAAYPECHPQARSADADLAHFKAKFDAGANSAITQYFFNADAYADF
LERCTAAGIHAPIVPGVMPIGRFARLVQFSEARGIEVPRWIRRRMEAFGDDNASIRAFGI
EVVVRLCERLLAMGAPGLHFFSLNDGDRVAEIWRALGLPPRLGAGATTALAR
>A0A395SNZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium longipes|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFENTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPEHEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAIYPEWEATGLEAGVRAEAINSRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGNPKTRQDINNLFVKHIQGELSAIPWSE
EELMAESSTIKPYLLQLNSKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PANEWDILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVNGSTEANPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNLIHHDY
VSKDALWEVLSS
>A0A520VU95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MLELSVEFFPPKTGEGISRFNKAADELVPVGFGFASVTYGAGGSTREGTLTAARELKKRF
KEGVPHVSCYGSDKASIFELLKTYSNDGFSRLVVLRGDLPSGYGGLGEFKNAVDLVRFVR
REFGDQFKIEVAAYPEKHPQSTSFEQDIDYFVEKVNAGADGAITQYFYNSDAYFSFVDEV
QSRGVSVPIVPGIMPITNFSQLARFSDSCGSEIPKWIKHRLSDFGDDRVKIYNFGINVVT
RLCKDLIRAGCPGLHFYSMNQSEPIIDILSGIEFTTDG
>E3QAK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)|TrEMBL
MEKITDKIAALPANANYFSLEFFPPKTAMGLSNLRVRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKSE
YRDAEDSDVDDAEDFVWAADLVRYIRKSYGDYFCIGVAAYPEGHADESHPLGQSFEHDLP
YLVEKVQAGADFIMTQLFFDIKAYDEFEKILKEHPSGAFRDIVILPGLMPIQSYQMIKRT
TKLSHAKIPDNLMARLDAVKGDDEKVKQVGVDILSELVEQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDHSLEDEEAVIDDGPGVPVSIPEVQLNGLAPIHPAARALSGRRH
SSMGSSDPHNRIIVPSASNPAYETTAVELSSTEPVNTRANTLAISEGVGAVGREATWDDF
PNGRWGDARSPAYGEIDGYGVSLHMSVTQAVRLWGTPKTVQDINNIFIRHIKGQLSAIPW
SEEELLPESNIIQQELLELNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVEL
FIPSSDWASLVARLNEVTDNTICFYAANAAGDFVSSDASGGLVLEGTEASTNAVTWGVFP
GKEIITPTIIEEVSFRAWAEEAFNIWGEWSKVYGKGSESESLLERIRSDYWLVNIIHHDY
IDRDALWKLLSGEKEN
>A0A315B1N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. T6-20|TrEMBL
MSGLKLPISLEFFPPKTPEGAEKLRGVRQALYGLKPEFCSVTYGAGGSTQEGTFATVGEI
LAEGVSAASHFSCIGATKASVREELATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLV
AFIRSETGDDFHIEVAAYPEIHPQAKSPESDLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGYGDDIASIKAFGL
DVVADLCEQLINGGVPALHFYTMNQSAATTDILRRL
>A0A0R2LPR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus kimchiensis|TrEMBL
MTETKNFPTLSFEVFPPNSEVGVGKLTDTLDQLKGLNPSFISVTASNHKLNYEKTTIDLA
KYVNDTLDCPTMVHMPAAYVTKAEVSSILDQLEAMHINQILALRGDIVDGYTPETDFTYA
SDLTKFIKQQKPYFEVSGACYPEVHPDSKNRIDDVKHLKEKVDSGCDQLITQLFYDNEQF
YRFQEECAIADINVPILAGIMPIVNRKQALHVIENCAAHLPKKFINILDKYKDNPVSLKE
AGIAYAVDQIVDLVTNDVNGVHLYTMNKSDTAKHIFSNTASLFNLEAQVEE
>R5NT05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:603|TrEMBL
MRIPELFKEGKTVLSFEIFPPKKTSSIDTIYNTLDELSDLNPAFISVTYGAGGNTADSKT
CQIASVIQDKYNITSAAHLTCVNCTKNDIDVILGQLKEKGIQNILALRGDINPDIPPKHD
FKYASELVTYIKEHGDFSVSGACYPEGHMETESIIDDIKHLKIKVDAGADHLMSQLFFDN
SHFYDFLEKARIAGIDVPIEAGIMPVINKNQIERMVSMCGASLPVKFTKMMQKYEHNPEA
LRDAGIAYAIDQIVDLISNGVDGIHLYTMNNPYVARRISESISSLL
>A0A537LWJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrabacteria group bacterium ANGP1|TrEMBL
MSGASRPNGVRQGLAARRFVLTVEIATPRTREPFEQAIRPLLVLAREVRDDPRIDAVALT
DRSRSDQDHDPILTGHRVAEESGKMPIVHWAGKDRILRHLEADLQRAEALGLDTFLLVTG
DKVRQPPGGRPVRYLDSVNALAAARQRSQELLLAAAVSPFKYREEELVNQYLKAGKKIRA
GADFLMTQIGWDLRKYEEARRVLNERGYHAPLMAELLLLTPARSRRIRRVGLAGVTITGD
LAQRLEEEAASRDGGRGFAFRRLALQTASVRDLGYAGAQVSGLDTYPDIVRLLDEVERAT
RECPTPEARRQAWRELLTLQNGRAVQVAPAHGLYLKPGAMGERSGGARAREWARFRIMDV
IDHLLFKEGAAGARVLAPVLRRLDARSGVGRLLLRVERAIKGPLVGCQTCGFCRLPETAY
VCPETCPKGLANGPCGGTKDNVCEFGDRECIHNQIYRVSKRAGLLAHLEETLIPPVPETA
WDSCSWVAHFRGEGPKVTRLPGDRA
>A0A0J8YTP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacteria symbiont BFo1 of Frankliniella occidentalis|TrEMBL
MSFFHANQREALNQSLAEINGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRNIAQDYWNNGIRHIVALRGD
LPPGAGKPEMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFAAMTNVRVPGWMTSMFE
GLDNDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPETVVNA
>A0A7W4TYH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. RAS22|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNAEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLATAAHLTCVDASRDEVHQVVDEFRNVGVRHFVALRGDPSTGIGTAYQ
PHPQGYENAAALVKGLKELGDFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPAFLDERFEGYD
EDLEGRARVAAEVAAEQIADLQRRGVSEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A5J5DT21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium vespertilionis|TrEMBL
MTTPMFSLEVFPPKRNAPVGTIYDTLDGLEGLKPDFISVTYGHGTASDRTATARIAHTIR
TEYGIPTVAHLTALYSDHEVIDHALEMFDEAGVQAVLALRGDYLPDQEPVGAFPHASDLV
AYIREKRPDLKIFGACYPEGHYQAESLDEDIANLKKKVDAGASHLISQLFYDDDDFYRFL
DKARAAGIDVPIEAGIMPVRGAKSVRRMAERNASRIPAKLNRILDKWADNPEALRAAGIN
YASDQITDLVAHGVDGIHLYTMNHPGGTRRIWQNVGCLFAR
>A0A414Q2G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium mortiferum|TrEMBL
MKIKELFKQKQPTISFEVFPPNKIYTLEKVYEVIDELSLLKPDFMSVTYGAGGSTRRNTV
DIASKIKNINNIEALAHLTCIGATKKEIDEILKDLNKNNIENIMALRGDIPQECENKIGE
FSHANDLIKYIKEYGDFSIGGAFYPEGHQETNDLLDLFNLKTKVDSGTDFLISQIFFENE
KFYEFKEKLGKLNIKTPLIAGVMPITNGKQIRRITSMCGCSIPEKLKKILDRYEDNPIAM
REAGIAYAMEQIIELISDDIAGIHIYTMNRVEASKKIMENIGNILRKRDENYGY
>A0A258W7D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrio sp. 28-41-41|TrEMBL
MKVIEHINRALQKSNPPEFSFEIVPPPRGRSVKEIIDIAEDLSKLDPPWIDVTSHASSAY
YHENSDGSIVKRTFKKRPGTLGICGIIQNRFRIDTVAHILCQGFTKEETEDALIELNYLG
IHNVLALRGDSLNYSKEVSKNRSINQYASDLVTQIKGMSTGQFIEEISNSEPLDYGIGVA
GYPEKHFEAANFKTDIQFLKKKVDAGADYIVTQMFFDNQKYYQFKKACLDAGITAPIIPG
LKIIKNVAQLKSVPKTFSVDLPERLVDEITSNPAHVEEIGRRWALAQVEDLIKNDEKNLH
FYIMNDAGLVIDLVKKFI
>A0A4V6XB66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella jiaozuonensis|TrEMBL
MANGLPSTRPGGPPTIRELLASGDRSFSFEFFPPKTPEAEEVLWRSIREIEQLHPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVSHSRDELRSVIGAYAGAGVRNMLALR
GDPPGGPNQPWVAHPEGLNHAVELVELIRELGDFSVGVAAFPDKHPEATSLEADAQVLAA
KAQAGADYAITQMFFGADDYFRLVDRSAALGCEMPVLPGIMPVTNIKQIQRMAELTGMAL
PDAVTSRLLAVEDEPTAVREVGIEIATELCERLLAGGAPGIHFITLNRSTATRQVFRNLS
STVVS
>A0A3S1VNX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.13.2.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A143I1I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter asburiae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKAVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A238JGI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagimonas phthalicica|TrEMBL
MQPQISFEFFPPRNVEGTFRLWDAVQVLAPLDPSFVSVTYGAGGTTRDLTRDVVATLHKH
SGLRTAAHLTCVNATRDETLGIAQEFAKAGVKDIVALRGDPPKGENSFTAHPDGFANSVE
LIEALAETGDFTIRVGAYPDKHPEAADMQADIDWLKRKLDAGATEALTQFFFEAETFLRF
RDACAKAGIDKQIVPGILPIENWKGARNFATRCGTTIPSWVDDAFAKAERDGREDLLATA
ICTELCSDLIDEGVDKLHFYTLNRPELTRDVCFALGVTPKVKLEHVA
>A0A0P8YX89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxobacter pfennigii|TrEMBL
MKLTELFQRGEFVVTCEVGPPKGFHIEHLLHEVETYLKDRVTAVNVTDNQSSVMRLGSLA
TCKALKDKGLTPIFQLTCRDRNRIALQSDILSAAMLGIENLLLLTGDHTRMGDNPQAKPV
FDLDSVSLIHMVKKLEQGEDLAGNALEGEPPKFAKGAVVSACSDSVDVQLAKMERKVKAG
AEYFQTQAVYEPEKFIKFMEKAKQFGVPVMLGIVIPKNAGMAKYMNDNVAGINVPQEMIE
ELKKDKEKTKAGITGVEISARLIKECKQYCQGVHIMALGWESKVPDILAQAGI
>A0A0G4M6R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium longisporum|TrEMBL
MGSTGVDTVAQSSNATYNRPKTRQRVQKAPPVLDVPDIDEDAAERKRVLNVLAQRRYRER
KREARTKSKDTKQQDDLSAVDGIQPPASSSHPDGSLSSVSPPDAPRTSVSPNDLLLTSGL
DLGLDMPWDAVSLEPTSVSTLAETFPCASFETIMWDSLSTPSSSSPPGSSSSLSSNLIAN
STAMSSINRSHLGAPAAPSPGEPFAPPVPVDDFTDRYLLPMADLTLLRAFLSIADRLGCA
TELWSPTSNSPFNKGGGTPAALLPPNFRPTPTQRQLPHHPMLDFLPWPSVRDRIISIFNM
PEAMRPPGARDALAPIKFAYDLEDEAEGVRIWGGDPYDATGWEVGQTFFERLQTCITGRR
NSRGKEGTQAGQRGRRGLPPNPTATMHIKEMLADAERDGQPSFSFEYFPPKTAQGVQNLY
DRMDRMYNFGPKFIDITWGAGGRIAELTCEMVTQAQSVYGLETCMHLTCTDMGLDKVNDA
LRKAYKAGCTNILALRGDPPREKEKWVAADGGFEYARDLVKHIRATYHDHFDIGVAGYPE
GCDDNKDEESLLDHLKEKVDMGATFIVTQMFYDADNFVRWVGKVRERGITIPIVPGIMPI
ATYASFMRRAKHMNCSVPQEFMDALEPVKNDDNAVREVGKVLVAGMCRKILAAGIHHLHF
YTMNLAQATRMVLEELNWMPTSERPLKQALPWKQSLGLGRREEDVRPIFWKGRNKSYILR
TQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEQNIKKWGEPQTVQDIATLFVRYLRN
EIDCLPWSESPLTNEADPIREDLIALNKRGIITINSQPAVNGVKSSHAVHGWGPKNGYVY
QKSYLEMLVHPDLYPEIISRIEKHPDMTYYAVTKSGNLKYNAPSDGPNAVTWGVFPGKEI
VQPTIVEGISFVAWKDEAFRLGLDWAHCFEQSSPSRVLVELNNDFHQQREIFDLFEGLSV
KEYDDIKPVVKDVAPDAVSAPTNGTTNGIAVPAA
>A0A1H7ZSR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Frackibacter sp. WG12|TrEMBL
MGQNKLKESILNKDEFTVTWELVPGRGAREANQEFIFEGAEQAAESDKVDGITITDNPGG
NPAISAEYLGMKAEEIGIPALVHFTCKDKNRNQMESFLYSLEREEVNNILVMTGDYPVGG
YDSRSRPVYDMDPTQVLEMVTDLNDGLKYKDAFGRSVELQETNFFPGAAVSPFKQLESEQ
MVQYYKLKKKIEAGAKFIIPQLGYDARKFHELIQFIEMNDWDIPVIGNVYVLSYGASRAM
NANRIPGCVVTDKLVDKLAEEKEADDKGKHARLMRAAKMYAYMKGMGYAGVHLGGHGMGI
EDVEFIVDKGEELAPNWQDYIHEFEFPMEDGFYYFEKDEETGLNTKQPAARTHKPSKGLM
NRTFRVMHHALFEPDSPFFKPMQYLCKSVDDSSLEKPFEFMERVIKTVSNDCQECGDCAL
FDLAYICPMSQCPKNQRNGACGGSRDGYCEVYPNEKKCLYVRVYDRLKAYGEEKQLQEYQ
IPPVNWDFHHTASWLNFFMGRDHSAKRLGITPPGSESEGKSKKA
>A0A1S8YHG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Izhakiella australiensis|TrEMBL
MSFFHANQREALNQSLAELGGRFNVSFEFFPPRTKEMEDTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELKTIAEDYWSSGIRHIVALRGD
LPPGSGKPDMYACDLVSLLKEVGDFDISVTAYPEVHPEARSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVSAA
>A0A0S8GEN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR_3 bacterium SM23_60|TrEMBL
MLKTRLKYHKIITIEMLLPIVHRRYELASTIAPFKEYIDAVNIPSNPLGKLRPDALCYAH
IVQEGTSVEAIPHCVARHFTSLSFESHLLGAAGLGIHNILCVTGDFPVEGQGRFELNSRK
LLRIAQNLKHGVTTARKRIEPIDMCLCTSFNANVPNVYGEFVKAREKHNYGAEVFFTQAI
FMPDDFLRILQEFRAQNRDVYVIAGLSFLHTKKRAVALMKHLTIPYEYIMRIEEEDEHEM
LLETARTLKDYVDGFYVIPIRKYDKALTFVKQLRKLLDQ
>A0A2N0ZNI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. Sarcosine-3u-12|TrEMBL
MTKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALCA
RGETDIAPHMSCIGDDKSQIAELLDLYKGLGIQRLVALRGDLPSGQVGMGELPFALDLVK
FIREYSGDHFRIEVAAYPEMHPQARSFEFDVDNLVNKYQAGADASITQFFYNADSYLYLR
DTLEKRGIDTVAQPLVAGIMPITNSSNLVRFADSCGADIPRYVRKRLADFGDDRTAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLIA
>A0A517M3A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rosistilla ulvae|TrEMBL
MSLSQLFRGGGCPISFELFPPRTPAGFESLYQHVDSLKQFDPAFFTCTYGAGGSTRDSTL
DVVREVKRRTGKPVASHLTCVGSTQDQLRSYLTEAGTLGVDYIVALRGDPPKGETSFTAV
EGGFRFANELVEMIHAEFPEFGIAVAGYPEVHQEAVDADVDMENLKRKVDAGADCVVTQL
FYDNDDFFRFRDACQAAGIEIPIIPGLLPITNFAQAQRIASMCKAKLPQGLVDRFNENDS
AEWQLKVGIEHAQQQTNDLIRRGIDGLHLYVLNKSQAAAEVLAGVDRG
>E1VBW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)|TrEMBL
MKFDDEPVPGYSLPVLPGHVSPGRLERVLRAGRFAVTTEIDPPDSADPAEVLRRAAIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYATILQMSCRDRNRIAMQGEILGAAAMGAC
NLLCLTGDGVQAGDHPHARPVFDLDSLSLLEMARRMRDESCFESGRPIDSPPRMFLGAAA
NPFVPPRAWRAQRLAKKVAAGARFIQTQYCFDTAVLRDFMAEIADLGLLEGPDRIHVLVG
MGPLPSARSARWVRDNVPGIHIPDSVIKRLEGAQNQREEGARLCRDILQEVREIEGVSGA
HIMAYRQEATVARIIEETGVLEGRVPWYPGRDDPTELNPEAPDAAGDLPAAASS
>A0A5C6FR22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crateriforma conspicua|TrEMBL
MKLTSAYQSADCTISFELFPPKTSAGLDKLCQNVDRLTDFGPKFMTCTYGAGGSSQGMTL
DVLRQVKSRTNLPVASHLTCVGATVPQLCDFLQQATDAGVDYIVALRGDPPKGSEKFVQT
EGGLRYANELVELIRERFDHFGILVAGYPEVHQEAPDAQTDLTNLKRKVDAGADVVVTQL
FYDNADFYRFRDDCDRAGITVPIVPGILPVTNFAQAKRIATMCKSAIPASLEDAFGKCQN
ADEEFEIGVEHARRQTIDLMENGVPGIHYYVLNKTEAAERLLQGLSFAV
>A0A1W9U819|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterium sp. 4572_20|TrEMBL
MALKETLDGGKFAVTTEVGPLKGTDISEIMELAEILNGKVDGVNVTDQQSAVMRLGSLAA
CSILVEKGLDPVFQMTCRDRNRIALQSDLLSASVLGINNVLVISGDYPTLGDHIDARDVY
DLDSEQLIWTINRMNEGYDLAGNELQGKTDLFVGAVVKPVSDTDESFELQLTMMEKKISV
GARFFQTQAVYDVEVFERFMKRAAQFKVPVLAGVIPLKSAGMARYMNKNVSGVFVPEHMI
DDMARAKDKVATGLEIAAQLMRDLKDLSQGVHIMAIGWEKKVPDILRLANLA
>A0A1K1PFN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus flavefaciens|TrEMBL
MKTAELFEHKTVFSLEVFPPKPDTDESVIYDTLNELSDISPDFISVTYGAGGGQNGCKTI
QIASDIKERCGVESVAHLPCIDLTKAQAVEILDSLQAHGIENVLALRGDRRGDLSETGDF
RHASDLISFIKERYDFNIIAACYPEVHPESVSAVDDLKWLRHKVDCGADHLITQLFLDNK
YFMDFSEKARIAGVDIPIEAGIMPVTNKRQIERMVKLCGVQLPKKFVRVLEKYEHNETAL
RDAGIAYAIDQITDLIAEGVDGIHLYTMNNPYVAKKIFSAVESLISVSSCALA
>A0A845B372|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allopontixanthobacter sediminis|TrEMBL
MNSPLDPVHEARTAVDTPLFASLPGDISASFEFFPPKTEKMEAILWESVQQLKPLNPDFV
SVTYGAGGSTRERTHNTVARIIAEAHMPAAAHLTCVDATKAEIREVAEHYWEAGVRHIVA
LRGDAGEPGAPFVPHPDGYASAADLVAGLKEIADFDISVAAYPETHPDASCPDSDIDNLK
RKLDAGATRAISQFFFAPETFFRFQDRLAAKGVTAPVLPGILPVTNVAQARKFAGACGAE
IPAWMDGLFEGLDERPAARQLVAATVAAELCRRLYAGGIRQFHFYTLNRADLAYAICHML
GMRPHGDVK
>A0A848W8K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTQNSAHISVSFEFFPPKTDAAERSLWEAVCRLAPLRPAFVSVTYGAGGTTRERTHATVT
RIVRETALTPAAHLTCVEATREQVDGVARTYWDSGIRHLVALRGDPPDGAAGYHPTAGGY
DYACDLVTGLRNVADFEISVAAYPEVHPDAPSAAFDLDNLKRKIDAGATRAITQFFFDNG
AFLRFRDAVAAAGIDAPVVPGIMPVTNFNGIRRFAEGCGASIPASLAQAFEGLDDNAEAA
QRVAKQVASAQCLDLAEHGVREFHFYTLNRAELTFAICQQLGVVAEDAPVAVDQEAAR
>A0A7W9W3N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oribacterium sinus|TrEMBL
MSIVDLFQEKTVFSFEVFPPRRNSPIETIYDTLDELRDLKPDFISVTYGAGGGKNNQSTI
PIAEHIKKVCEVPSVVHFPCINLTKQDVLEKIEELKTAGIKNILALRGDIPEGEENRGDF
RYASDLIAFLKEHGNFHISAACYPEGHIESADRVEDIRYLKNKVDAGAEHLISQLFFENK
QFYIFQERCALAGIDVPIEAGIMPVINKRQVLKMASLCGVKVPKKFQNILDKYEDNPIAM
RDAGIAYAVDQIVDLVTHGVDGVHLYTMNNPYIARKIYKATHSLFESTQKGNPGGSSASA
>A0A0G3BDY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schlegelella brevitalea|TrEMBL
MSNLSSGLPISLEFFPPKTPDGVDKLSAVRQKLYALRPEYCSVTYGAGGSTQDGTLQTVR
SILAEGCDAAPHFSCIGASKDSIREKLQQFKDEGIRRIVALRGDLPSGYGGFGEFRYASD
LVAFIRAETGTHFHIEVAAYPEVHPQSRSAEADLQAFIAKVQAGADIAITQYFFNADAYF
RFVDDVRKAGVDIPVVAGIMPITNSSQLMRFSDACGAEIPRWIRTRLQGYGDDKASIQAF
GLDVVTQLCERLRAQGVPGLHFYTMNQAGATTEICRRLGLGG
>A0A6I7NNX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneolaceae bacterium|TrEMBL
MKVIEHYDKATEPLISFEIIPPKRGGSVQAVFESLDKVVEKVHPPFIDVTYHAAEAYVEE
QQDGTLKRVVRRKRPGTIGLCAAILHRYGIDPVPHLICEGFTKEESEDALIELNYLGIHN
VLAIRGDNTGNQISLNLNGTANKYAIDLVRQIKKMNQGTYIEDIINAEPTNFCVGVAGYP
EKHFEAPNLDWDIKRLKDKLDAGADYVVTQMFFDNKAYFNFVEKCREHGIEAPIVPGLKI
LTTPNHLKTLPKYFYLNIPDELTAEVDANPGRAKEIGIEWTRQQTLELMESGAPGIHFYI
MGDPQPALDVIDFVRKK
>A0A8I1V062|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MAGRKKEKGPGMSLKSVIEGGAPRVSFEFSPPRSAEAEVSLWNAIRRLEPLAPAFVSVTY
GAGGSTRERTHATVRRIVEETSLKPAAHLTCVAAPRGEIDDIVRAYWDAGIRHIVALRGD
MPDMQGSYAPHPDGYRSTPELIAGIRKIAPFEVSVSFYPERHPDSPSHAHDIDLLKAKMD
AGASRALGQFCFDNDQTARFRDDAASAGITIPVVPGIMPTTNFRGVERMAARCAAAIPGW
LARAYEGLDEDVESRRIVAAAVLADQVEQLRARGFDQFHFYTLNQANLTYAACRILGVRP
KE
>A0A421K6I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium symbiont of Stewartia floridana|TrEMBL
MNDQTKQQIFSFELFPPKTEKGMENLKANVQQLQSLNPAFFSVTYGAGGSTQQRTFDTVD
WLVEQQIDAAPHLSCIGADQEEILEILERYKTQGIKRLVALRGDLPSGTGLGGLGELNHA
NQLVELIRQHFADHFHIEVAAYPEFHPQSATPQQDLENFKRKVEAGADSAITQYFYNADA
YFRFLDECQRLAIEIPIVPGIMPITNFTQLARFSDSCGSEIPRWLRKRLESYGEDLDSIR
DYGMEVVSDLCERLLAGGAPGLHFYTMNRSTQCQQIWQTLGL
>A0A2A4YRE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSKATFSFEFFPPKTDKTTELLFKAIEDLKALNPKFMTVTYGAGGSTRDKTLQIIKRMIA
DTDIPTASHLTYINSPRKEMYALADELWENGVHHIVALRGDMPADLEWPLDPDAEYFQYT
SHFVAALKARQDFEISVGAYPEKHPDADSMDKDVEALMKKVDAGANRAITQFFFDNNVYY
EFLEHCEKANIKAPIVPGLLPIHDFKSMCGFAGRCQASVPKWLHERFSGLEDKPEDARKV
ALDLLVGQSEDLVKNGVEHIHYYTLNKSDITTQAVEAIS
>A0A2N3P411|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. S06B 330|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATAHQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKEDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VEFIRQESADHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVQQLGVTIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVNSIQAYG
EEVITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A3M1J303|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
IRSYADIGIRHIVALRGDPVEGSGGVYRPHPGGYETSADLIAGIRRIGDFEISVSAYPEK
HPESPDFEADFDMLKRKIDAGASRAITQFFFDNDLYYRYLDRARARGIDIPVTPGIIPIH
NFRQVSAFAKRCGTHVPGRIARRFEGLDEDPETTKLVAATIAAEQVMDLAAQGVRDFHFY
TLNRGDLVYAICHLLGLRPKVAAREVR
>A0A1G8JKN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger marinus|TrEMBL
MTRPEISFEFFPPRNVEATFRLWDTVQALAPLKPRFVSVTYGAGGTTRELTRDVVAALHK
RSGLRVAAHLTCVDATREETLGIARQFREAGVQDIVALRGDPPKGSSGFTAHPDGFASSL
DLIAALREAGDFTIRVGAYPDKHPEAADAQADVAWLKRKFEAGASEALTQFFFEPDSFFR
FRDACAAAGIDKPVVPGILPIENWKGARRFAEATGTKIPGWVIDLFESPQAEGRQDQIAT
ELCTRLCQDLMAGGVDKLHFYTLNRPELTRDVCAALGVTPETALENVA
>A0A3M0FPI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. PP-CE-3A-406|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGLSFEFFPPKSEKMETQLWEAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQPHPGGYENATALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPVDKVAAA
>A0A429SMM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC05292|TrEMBL
MALGTASTRTDRARTVRDLLASGDPSYSFEFWAPKTEKGERNLWDALRRIEAVAPSFVSV
TYGAGGSTRGGTVKATQQIASDTTLTPVAHLTAVDHSIAELRNVIGQFADAGIRNMLAVR
GDPPGDPMGPWVAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSAQKAGCETPIIPEVMPVVAVRQLDRLPQLSNAVF
PDAVKERMLAVKDDPAAVRSMGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHKRA
>M6G2L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans str. 2006001854|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A3D2P2F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MNISFELFPPATSNGIGKVVEIARQLADFQPDMISVTYGAGGSGRERSSRLVAELNKPGF
PAITAHITLSGQSKQDVLQQMDEWQEHGVKRFVALRGDMPDMARPFKPHGDGFSSSLDLM
AHLASHGAEEIYGGAYPEGHPESPSQSAELDHLKAKQDAGATALITQYFFEVDCFLRFRD
RAESHGITLLIIPGILPVANFEKAKGFSKRCGASIPQFVHDRFAGLHNNPH
>G8T8V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niastella koreensis (strain DSM 17620 / KACC 11465 / NBRC 106392 / GR20-10)|TrEMBL
MKVIDHIRQAKDSLISFEILPPLKGKTINSIYEHLDPLMEFKPAFINVTYHRSEHVFKKK
ADGTFEKVEVRKRPGTVGICAALMNHYRVDAVPHLICGGFNKRETEDALIDLNFIGVDNV
LVLRGDAAKNETVFEPEKGGNSYAIDLLKQVQNLNTGIYLEEDIRDGFKTDFCCGVAGYP
EKHFEAPNLQTDLAFLKAKVAAGAEYVVTQMFFDNQKYFDFVKRCRENGITIPIIPGLKP
ITSKKQLSVIPRTFHVDIPDDLANEIMNCKTDVEVEKVGTEWLLLQSKELKKAGVPVLHY
YTLGKPKVIYNVVKEIK
>A0A539DKL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MGLLKTGLFERHGIRAIGIAGHPDGHPSMNAEECWRFLKLKCADIESRGMAPLIVTQFGF
DATPFLVWLKELRARGIGAPVRIGVPGPAKISTLLRFAAHCGVGASANVMAKYGVSLSRL
LGSTGPDRLVADLQRGLGPEHGPVRLHFYPFGGLERTVEWIRAYSGAH
>D3VH67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / CCUG 14189 / LMG 1036 / NCIMB 9965 / AN6)|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPSTTEMEQTLWQSIDRLSRLKPKFVSVTY
GANSGERNRTHSIIKGIKEKTGLDAAPHLTCIDASREELRDIAHDYWQSGIRHIVALRGD
LPNNCCKPEMYGADLVELLKEEADFDISVAAYPEVHPEAKSAQSDLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFSTMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPV
>A0A537TQJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MFSEPRASRFVRPRGDGEPRHIRVSFEFFPPKTEEMEKTLWESVTRLAPLKPNFVSVTYG
AGGSTRERTHSTVKRILAETALTPAAHLTCVAATREEIDSVIRNYCTVGVRHIVALRGDP
LGGLGDRYAPHPGGYCNAADLVAGIKRLSDVEVSVSAYPEKHPDSSTVEADLDMLGAKVD
AGATRAITQFFFENDLYFRYLDRVRARGIDVPVVPGILPVQNFKQTKAFAARCGASVPDW
LAERFDGLEDDAATRKLIAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAVCHLLGLRP
SQETDALPLPIVEKERA
>D5U4H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira murdochii (strain ATCC 51284 / DSM 12563 / 56-150)|TrEMBL
MNNVENFIKKLENKNEYTFTLEISPQAKYDLGYVEEKINNSNISDYIDSFVVTDSPFANL
KISSILAALQLKQRLNNNKPFITTQTMRDKNSIALQNDLIGANYFDLRMILAVTGDAVAN
GNQKQAKAVFEGNSNLLINIIKNLNKGKSLGEFVFKEPLKHIYPFCVINSYAKNNDSLKV
RLAKKANSGVKAIFTQPIYEIERLELLLKWIDELPLKEKPMLIPGFFPVLTYKTAYFIYY
KLPGAYIPEDWLNKLKEASDKSPEEEKKVAYELSANLFNSMIKKHKKMHIMSMNNYDFVV
SLLKSI
>A0A3N5YYC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MLFNFREKLNSSKFMVTAEVSPPKGTNFSASLENARQLKGIVDAINVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNVCLMTGDFPSCGDHPGSKP
VYDLDSVQLMQVVKKLNSGIDFAGNKLDGGTSFCTGAVSGINPEKTLQLIKLEKKAKCGA
DFVQTQAVYDVGMFEEFMESINHLEVPVIAGLIPLRSLSMAEFMNENISGISVPEEIMFR
MKEASNPAEEGLHIASETIKELMRLSRGVHVMPIGSHKNTPRLLSMAGISGK
>A0A286E2I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alysiella filiformis DSM 16848|TrEMBL
MNAPHQHQKKLSFEFFPTRTEQGRAKQVITRKQLSQFNPAFFSCTSGAGGTTREGTLQTI
QDILSEGIAAAPHLPCIGMTADEIKVLLNEYKAMGVKHIVALRGDIPSGIGFGGDGLRYA
NELVELIKNEHGNDFHVEVAAYPEFHPQARSAEDDLNHFVRKVKAGADSALTQYFFNADA
YFRFVDDVQGRGVDIPIVPGIMPIASFTKLARFSDTCGAEIPRWLRLKLQSYADDTAAIK
ALALDVVTDMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>J2UBE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. CF444|TrEMBL
MTQHNFSIEFFPPKTPEGTEKLRVTRAKLAELQPKYFSVTFGAGGSTQQGTLDTVLEIMR
EGHIAAPHLSCIGSSRATLRDILSNYKSHGIKKLVALRGDLPSGFGAVDTASGEFHYANE
LVEFIRAETGDWFHIEVGAYPEMHPQAKSPQDDVQNFARKIKAGADAAITQYFYNADAYF
NFVDEAEKLGISAPIVPGIMPITNYTQLMRFSDMCGTEIPRWIRLKLASYGDDGESIRAF
GLDVVTQLCEQLLEGGAPGLHFYTLNQPAATMAIWQRLVA
>E1L9Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella atypica ACS-134-V-Col7a|TrEMBL
MTLREKHHNGQFTITVELDPPKSSSAQKVFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNEGIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDHGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNGA
HFVQTQPIYDLEQAKRYIDKMSEFNVPIMLGLIPLKSFKMATYLHEKVPGINLTQDILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A1U7P140|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus marmoris|TrEMBL
MTTRISIELVPRSRSGLRAELAAVAEHLPGADTINIPDFPRFSTRSWHGCGFARPRYRAI
PHIRAVDLNPREPLPMAAHLDEHGIDEVIVITGDAPSDMSAKVYNVDAEAAIRRIRRELP
HLKIYAGLDPYRQSLAREQDYLERKLEAGACGFFTQPFFDLRLMDAYADLLPEGAEVWWG
ATSVTSEGSEGYWRTRNHAVFPRQFQPTLEWNRRFAGELLAFARERGQHAYFMPIKADVV
EYLGGIV
>A0A3C1IMN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phascolarctobacterium succinatutens|TrEMBL
MTSEKIIDILKNGKIHLSCELFPPKQGAELQNSLEIVNRIAASKPSYMSVTYGAGGSTVG
YSAALAKKVQDNGMPALAHLTCVKADEAKLAEVLGQLHGLGVKNILALRGDIPADMQGEE
IGSFAHASELMRFVKQQGDFCVGGAAYPEGHPESGSLEKDIENTKYKVDAGVDFLVTQMF
FDNTILYNYMFRLLRAGINVPVVPGIMPVTNAKQIIRICQLSGTKLPPQFRAMVEKFADK
PEALKQAGIAYATGQIIDLIANGFDNVHIYTMNKPEIFAGIMNNLGEIVDK
>A8TTR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|alpha proteobacterium BAL199|TrEMBL
MTKVPSISFEFFPPKDEAGEIKLWETLDRLAPYGPRFVSVTYGAGGSTRERTSRIVTRIK
RETGLEPAAHLTCVGATCDEVDEVARGWWDAGIRHVVALRGDAPAGSGGYKPHDGGYANG
AELTAGLRRIGDFEISVGAYPESHPDSASAEADLDNLKRKLDAGANRAITQYFFEADTFL
RFRDRCAAAGITTPIVPGILPVTNFQKVVEFSQACGATVPAWMADLFAGLDGDPETRQLV
AASTASELCMALMAEGVEDFHFYTLNRPQLAAAICRRLGVRPELEAAA
>A0A6B3HBI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8455|TrEMBL
WETDIGHFVDKCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLE
RFSQLSNATVPEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNST
ATLEIYENLGLHKQS
>A0A4V2UVX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidimonas ignava|TrEMBL
MACPLSFEFFPPKTPEGAAKLRAARQRLYAARPQFCSVTYGAGGSTQEGTFTTVAEILAE
GVDAAAHFSCIGATRQRVRAQLAELQRLGVRRLVALRGDLPSGYGLGGEFTYARDLVAFI
RAEFGAAFHIEVAAYPEMHPQARSPEADLQAFAAKVAAGADGAITQYFFNADAYLRFVDE
ARAAGVTVPIVPGIMPITNATQLMRFSDACGAEIPRWIRLRLQGYGDDTASIRAFGLDVV
SALCERLLRAGAPGLHFYTMNQAEPTLAILDRLGLAPV
>A0A2Z4J4T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cadmiisoli|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFYAPKTPKGERSLWNALRRVEAVAPDFVSV
TYGAGGSTRASTVKETEQIVADTTLTPVAHLTAVDHSISELRNVIGQFADAGIRNMLALR
GDPPGDPMGDWVPHPKGVTYAAELVRLIKESGDFCVGVAAFPEMHPRSCDRDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCVTPVIPEVMPVTSVRMLERLPQLSNAHL
PSTLKERILTAKDNPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>M5RMW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula maiorica SM1|TrEMBL
EESQFSIGVDHAREQTVDLIKNGVPGIHYYVLNKCDAAEKMLDGLDLCCS
>A0A101T6S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseoruber|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFYAPKTPKGERSLWDALRRVEAVAPDFVSV
TYGAGGSTRATTVKETQQIVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVLPVTSVKMLERLPQLSNAHF
PDVLKERILTAKEDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A1H6NL23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tardiphaga sp. OK245|TrEMBL
MTEINPATPTKLPNISFEFFPPKTEEMDRTLWDTIERLAPLTPSFVSVTYGAGGSTRERT
HATIVRLLKETALTPAAHLTCVGAPKSEIDDVVTRYHEAGVRHIVALRGDPTTGIGTEYI
PHPDGYKTSADLVASIRNRYPDIDVTVSAYPEKHPESADFDADIDTLKAKVDAGATRAIT
QVFFDNDLYFRYLDKVRARGIDIPVLPGIMPMHNFKQARAFVTRAGTTVPDWLAAKFDGL
DNDAETRKLVATTVAAGQVQKLAKQGVSDFHFYTMNRADLVFAISHLLGFRPNGAQKAA
>A0A2U8DUI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium drakei|TrEMBL
MKVTEIMKKKMSFSFEVFPPKIDKPTEPLLDTLEHLYEFNPDFISCTYGAGGTNAGRNME
ICKAIKDSGKSIPVAHYTCIGNTKEKMKQELQRYLDMGVDHILALRGDLPKGWEGTRGDF
NYANELVQYIKSNFPKFTIAVSGNPEKHFESYSFDEDITHLRIKQDTGADYIMTQLCHDV
DQYCWWVEKIRRAGVSMPIDVGVMPILSKDPTIRMAVSNGSSIPRDLAEIIARYGDNPED
FKKAGKEYSAKQIFKFINAGIDGLHIYSLNKWQDVTDIIKDVGIR
>A0A2N4UHI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp. JR1/69-2-13|TrEMBL
MNPNKAISLEFFPPRDTAAQEKLVRSAKQLLALEPAYVSVTFGAGGSTRTGTADTVRLLQ
NLGCDAAPHLSCIGATRAVLGDILDSYREQGIKRIVALRGDMPSGMGGDQGELHYASELV
AFIRQHSGDWFHIEVAGYPEMHPQSTSAEADLAHFIHKVKAGADSAITQYFFNADAYFDF
VDRMNAKGVDIPVVPGIMPITNYTQLARFSTMCGAEIPRWIRLRLADFGDDKASIKAFGI
DVITRLSQDLLDNGAPGLHFYTLNNAEVTMAIWRQLRLA
>A0A1F8PLQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_51_9|TrEMBL
MATPFKEVLNSGKFVVTCEVAGPKGANVEKTVHHIDLLKDKVDGINATDNQSANMRFPSL
GVCLLIKERGGEPILQMTCRDRNRMALEADLLFAYSRGITNVLCLTGDAITNGDHKQAKP
VFDIDSLQLLRAIRNMEAGKDMGGNDLVDGAPKFCAGAIVTPEAQPIEPQLIKFRKKVAA
SAEFFQTQAVYDMGNLRKFMEGARPLKTKVLAGIVLLTSAGMARFMNANVPGIFVPKVLI
DEMAGAEKGKALQKGIEIAGRMIKTIKDEKICDGVHIMAIGKEEVVPDILAAAGM
>A0A7V6A5F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans|TrEMBL
MTAPPPLERLSIQPIRGDTRPMSKLREVLSAGGFAVVVEIKPPRGTEVAEMLAPVSRLRG
RVTAFSVPDNEHARLGLAALAAGRLVQEAGGEPLVHLTCRDRNRLALESDLLGAASLGLE
NLLLVSGDYITLGDHPAAKPVYDADSVQLLQIARGLTEGQDSVGLPLSGRPSFFLGAVVI
PEADPLAPQLLKFEKKITAGAEFFITPPVFDLEKFRRWREQLPAPAVKILTGIKVLGAAE
VEQAAAGTWRKVYSVPPDLVQDLAGKEPEEILARGAAAAGSLVQRLKRGNLADGVYLKAK
GRTDLFQKILEAAGL
>A5FJS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / JCM 8514 / NBRC 14942 / NCIMB 11054 / UW101)|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAIDLVRQIKDLNCGQYLHEVIDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>F4CJ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 / CB1190)|TrEMBL
MNVRELLTTSVLVGDGAMGTMLHAAGNSLDQALPALNLTEPELVRTIHDSYVGAGVDLVQ
TNTFGASRLRLAEYGAADDVARINAAGARLAREAAARADRAVLVAGSVAPAVSVHQRRRV
AAEERRAAVREQVEVLVGAGVDVVLLETFGHLDELVEASEVALEVARRTGDVPVIAQATF
GSDRHTLSGHTPHEVVTALAGFPLAAMGVNCTLGPQGCLAVLRELRVHTAVPLTVQPNAG
LPRRVGPARFEYDIDADYFVRYTRQLLDAGAALVGGCCGTTPSQLAAAAAAVAEHRSQRA
AEVAERVAATAVVPERPETDGPFSAPGHVVAVELRPAPTGGVDEALELAAELQQAGVGLV
SVAASSSPRAQVNSVDLALHLHNRLGLTTLASVTTWDRTIMALQADLLGAHALGVRGVVC
ETGTPPLLGDYPHVDGIWDVDSLGLIELLAGLNDGTDYHGLRLGTKTSFEIGARVNPGSR
DPGRAAAGALDKIAAGAQFLITRPVHELAGLERVLEAVDGRVPVLVAVRPLTGFDEADYL
AHEVPDVTIPAATLAALQDAGPDARAAGIDLAVALADQVRGMAKGVVVTGGSDVVEAVRR
LLG
>N8W1W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 102529|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLHIVHQELQRLNPEFFSITYGAGGSTRERTLATIHDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGNHFHIEVAAYPEMHPQADSFDADIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERLEKEGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1H9DPR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas ureae|TrEMBL
MDSQKKFSPTFSFELFPPQTPQGIEKLRLTRQQLAQFNPKFFSVTFGAGGSTRERTFETV
LEIQSEKHVVAPHLSCIGSTQENIRIILEKYYEIGIRRIVALRGDLPSGMAQAGEFRYAS
ELVAFIRKEFGSSFHIEVAAYPEYHPQARSAQADFENFKRKIETGANSAITQYFYNTEAY
FHFVDSCESAGLSIPIVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLEGYSDDSASIQA
FGLDVVTDLCERLLKAGAPGLHFYTLNSANLTSIIWQRLNLKEYVQ
>A0A1I7E2K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kosakonia arachidis|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAVPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCASTGIDVEIVPGILPVSNFRQAKKFADMTNVRIPAWMSQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A521FSL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus aquaeductus|TrEMBL
MKRSLAVRDATTRNSLRQAFSGLGYEVIPFKKTQQSVLSCVPKDVRLTVTASPAKGQDAT
VDLAVALAGHGYTVAPHLSAQQVRDRAHLADVVARCREAGITDVFVVGGDPAEHPTQFRH
AHDLLVALHEIDHGFTDIGIGGHPEGHPTASTEVLFQALEDKAPLATHITTQIVFDPAAI
LTWAREVKDRGIDLPVHVGVPGAVHRQKLLRVSGGIGIGESAKFLKKQQNLLWRFFVPGG
YSPDKIIKGLAPHIGKPDNHIEGFHVFTFNDLGPTEAWRQRVLADLA
>A0A327KT55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoplanes elegans|TrEMBL
MSPSEPRASRVPHSRESLRVSFEFFPPKTEEMEKTLWESIERLAPLRPDFVSVTYGAGGS
TRERTHATVKRILDETALTPAAHLTCVAATRDEVDDVVREYLAAGVRHIVALRGDPVAGI
GTAYAPHPGGYVNAADLVGGIKRLAEAEKTDIEVSVSAYPERHPESPSDAVDLDMLAAKV
DAGASRAITQFFFDNDLYLRYLDRVRARGITIPIVPGILPVQNFKLARSFAGKAGASIPG
WLADRFDGLDDDPATRKLIAAAVAAEQVLDLVDRGVTEFHFYTMNRADLVYAVCHLLGLR
PPAAVPAAAAEAAA
>A0A3L7AQD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. BL4|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTEAGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVSVTERIATDTTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPQGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFEADDYLRLRDRVAAAGCDTPILAGVMPVTQISTIERSVQLSGAPF
PPALAARFERVADDPEAVRLLGIEQASEMSRRLLDEGVPGIHFITLNRSTATREVWQNLK
VGARM
>A0A3L0X4G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MGFHSARQVEALNQSLADLSGDIGVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKDPV
>A0A1Y5KQJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQASPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALETRIEHWQSQVQSLEQWAPA
WHASWQMPGLPAVTFHPPQAGWRLDESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPLWATRAGAHVLHTLERNVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A6S5TN31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQLKTALHDNTFVCIMEFVPKSSSERFASLEALMARQHLCGWPMTVAIADRVGSPFEMS
PLDAYSSFRQPLSALLHFSGKDRERHHLLEQLQQMDAAGLDQLLLLTGDRLPGHVPGQRP
VRYLESIAALQTVRQARPDWLLGAGMHPFKYREEEGGAQYFKAEKKLAAGADFLALQLGY
DASKHLEAIQWMRRQPHPKPLTACVMGLTLGRAKIFEHVAGIVVTPSMHDVLAAEAEVSK
AHAQARSLERLALQIIGLRLMGYAGIHLSGIHDLEQLDALERNLEHWQARLHSLEQWAPA
WHACWQVPGLPDVTFHPPGANWRLGESQVSASPKETARYHLLHGLHSLLFSRRNPLSQAF
GWAVQRPVWNTPTGARVLHRLERSAKRPLVGCDTCGTCRLEDTLYICPETCPKGLANGPC
GGTTLNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIDADTRHRSSWPTWFQAPAA
TTTIAKPCGSGLAPQSTTEATLKAPALHASEVPELDN
>A0A6N6JBE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoreibacter roseus|TrEMBL
MTKPAISFEFFPPRNVEASFKLSDAVQTLAPLEPEFVSVTYGAGGTTRQLTHEAVEAIQK
SSELTVAAHLTCVDASRDETLEVARAYKKAGVSDIVALRGDPPKGTDTFTPHKDGFTSSV
ELIEALKETGDFTIRVGAYPDIHPDAQDMSADIAYLKRKLDAGADAAITQFFFEADTFFR
FRDACVAAGIDKPILPGILPIENWTSARRFAERCGTKIPGWLDDAYTAAQRDDREDLLSI
AIASELCADLVEGGVEHLHFYTLNRPELTRDICTALGITQRTSLSQVA
>A0A8J3X7M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planotetraspora mira|TrEMBL
MALGLPSRLPERVPTVRELLAAGERSFSFEFLPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPRGADPLSEWIKHPEGVQYAEDLVRLIRQAGEFCVGVAAFPYKHPRSATIESDTEFFV
QKCRAGADYAITQMFFKADDYLRLRDRVAARGCDTPIIPGIMPVTQMSTIARSEQLSGAP
FPPEVAARFEAVADDPAAVRRLGIEHAAELCRTLLDEGAPGIHFITFNRSSATREVFEAL
APATATVRR
>A0A6J4X571|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius sp. associated proteobacterium Delta 1|TrEMBL
MPTPFKEALESGKFVVTSEVAPPKGTNLEKFKHHIELLKDKVDAMNVTDHQSSVMRFPSL
GGCLLVKEQGGEVILQMTCRDRNRMALQADLIFASYMGVQNVLCLTGDSIMLGDHKEAKS
VFDLDSSQLLETVRTLEKGKDLGGNELDGAVSFCAGAIVTPEADPLEPQLIKFEKKIESG
AEFIQTQAVYDLDRFKEFMDYARQFNVKILAGIILLTSAPMARFMNKNIAGVFVPQDLID
EMASAPKGQALARGIEIAGRMIKRIHDEKMCDGVHIMAIGKEEKVPDIMAAAGLI
>A0A4S1A0M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.156.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHEVDAVIQEFTDMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVA
GSAAA
>A0A0F2QU30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatitalea sp. BRH_c12|TrEMBL
MKTESTLEKVFNAGHIAVTGECGPPRGALPDKVREKAELLRGYVDSVNITDNQTAMVRMS
SFAASLILKQMDMQPVLQMVCRDRNRLGMQSEIIGAYSHGINTMLCLSGDHCKFGDHPMA
KGVYDLDSVQLIQTVRKMRDEGKFQGGADILNAPKMFIGAAANPFADPFELRVARLAKKV
RAGVDFIQTQCIFNIDKFETWMKGVRERGLDKEVYIMAGVTPIKSVGAARYMKNRVPGMD
VPDHIVERMAKTPKDKQAQEGIDICVESIQRILSIEGVAGIHIMAIEWESAVPEIVKRSG
LYPRPQV
>A0A4Z0PNM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter elongatus|TrEMBL
MKVTEHLSRADGKTLFSFEVLPPRKGENIQTLFSNIEPLLEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLNFLGIDN
VLALRGDPIKSEGHFKPEPDGHAYACDLIGQMANLNKGEYLDEEQDDTWATNFCIGTAGY
PEKHFEAPNYGADLRYLKHKVDRGAEYIVTQMFFDNEQFFSFEKRCRDAGITVPIIPGLK
PLTTKGQLTMLPRSFYLNIPEALAEAVHQAPNNEAARQIGIEWCVNQSKELMAHGVPCLH
YYSMGKSESIRRVAAELF
>A0A416HQP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eisenbergiella sp. OF01-20|TrEMBL
MKISELYQAKQNQGNPSKKTLSFEIFPPKKDSELKNIDKTLAVLCELNPDYISVTFGAGG
GANRNRTIELAKRIKQEYHVEPVVHLTCLHYDKAEIDEFARVLANAGLQNVLALRGDKNP
DMREKESFCHASDLIAYLKGKWDFCFLGACYPECHPESEDKVGEIRHLKAKVNAGAEVLL
SQLCFDNHAFFRFQEACRIADIQAPIIPGIMPVINAAQIKRMITMCGATFPVQFQKIIQK
YESNKEALFDAGMSYALSQIIDLLVSDVEGIHLYTMNNPLVARRICEGIRNIV
>A0A1F1J4L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC067H10|TrEMBL
MTTVHPALSYELYPPRSHASCDSLLKTIAELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLALRGDIPTENTRPLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAARLAGVEMPIIPGIMPVTSLTRLTKLCELAGLEVPRELAYRLETASEP
REMHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>A0A6A6ZV71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiobolus disseminans|TrEMBL
MHISQKLAQARAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQTVYGLETCMHLTCTDMEKSKLDEALKDAYQSGCTNILALRGDPPREREK
WEATAGGFRYAKDLVKYIKDRYGNHFDIGVAGYSEGSDDNDNVDELIDHLKEKVDAGATY
IVTQMFYDTDIFLDWVKKVRAKGIDAVIIPGIMPIHTHAAFLRRAQWTRCNIPAHWTEAL
EPVKNDDVEVREVGRGLVADMCRKLIDAGITHLHFYTMNLAQATRMVLEELELLPDVESP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPTSVKDLSDLFVRYMEGKLDALPWSEQPITGEASSIQPDLID
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVLVSPEYIAEIITRIERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAAVSPARYAIQGVVDTWYLLNIVHNDFHVTRGIFPLFDGLEVKDIDKPLHSASADL
PESDVHHEANGTRGTNGTNGETKEANGTEKQDPKLLDAAKSAALEVTNGVKNLAVSN
>A0A6N7RQ57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eggerthella guodeyinii|TrEMBL
MTQIADIYRTAKAEGRQPVSFEIFPPKGDLSLEAAHAMAGQLADLVPDFISVTYSAGGSG
NKQATAEVAAMVQFDFDVPTVAHLTCADATDEGLSRTIDDLRRKGIQNVLALRGDAAPAC
GEPRAGAFRYAKDLVAILAEEGFCVGAAAYPEGHIACIDARANVEHLKQKQDAGAAFFIT
QLFFDNAYFYRFWDAALAAGITVPIACGIMPFLGKAQIQRMVFMCGASLPSPIIKLLARY
EHAPDDLRRAGIEYANDQLVDLAAHGVDGLHVYTMNQPDIARANVAALRAAWRR
>A0A8C4HBZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dicentrarchus labrax|TrEMBL
MYVKLRVSDNFTHNFSSSKDSSRCSTPVLDADRSDRLRDKMRKRMESGDRWFSLEFFPPR
TASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHL
TCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAIDLVKHIRSEFDD
YFDICVAGYPTGHPEAESYEGDLRHLKDKVDAGADFVITQLFFRADTFLKFLDDCRAIGI
TCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRNYGIQQAVDMCRL
LLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWA
SRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLQMWGEELINE
ESVYEVFTCYITAQPNSRGHKVMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQPNI
NGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVDVHGRNL
TNAPDMQPNAVTWGIFPGREIVQPTVADPVSFMYWKDEAFALWIEQWAKLYEDESPSRMI
IKYIRDNYFLVNLVDNDFPLENCLWQVIDDMFELLDASPEQLNDGTLSE
>A0A833GCH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodoplanes sp|TrEMBL
MTVPHAVRPGGRFAQLLRERAFAITAEISPPLSADKADLLKKVLPLKGLADAVNVTDGAG
ARAHMSATSAAAFMVECGVEPVLQLTCRDRNRIALQSDLLGAAAAGVRNVMILRGDDPAR
GDQPEARPVFDYDTRELIAVAARMRDAGELASGRKIAAPPDFFIGAADLPVDPQPGWSPQ
ALRAKCEAGAQFVQTQFCMDGGLVARYVARLRAEGIVPRLRILIGVAPLRSARSARWIRD
NLFGSVIPDAIVERLDAASDPAAEGAAICLDLIAQLAAIDGVAGVHLMAPGHDEIVPEVI
AQARVRLS
>A0A1J0VND9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia mangyaensis|TrEMBL
MTGERRPETSGRRPTSFISRTPSVAQSLRDRTGHEVPFSVEFNPPRDAAGEARLWRAVRQ
FERMHPAFVSMTYGAGGSTKDRTVRITGELATETTLLPVAHLTAVGHSIAELRSLVGSYA
DSGIRNLLVLRGDPPGDPLGEWHKHPSGVEYADELVRIVRDLGDFHVGVASFPQGHHRSP
DLDHDTRHLAAKLRAGAEYSITQMFFDVEHYLRLRDRVVAMDPVEGAKPIIPELMPITSL
RTVQRAEELCGRTLPPAVMARLQRAAGTAPEEDRAAVRAEGIQIATEMAQRLIDEGAPCL
HFITLNFAKATSEVLTNLGYGAHTTATAVA
>A0A7X3FQ54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia marina|TrEMBL
MIDDNLRASRKTADQRPDLQLSFEFFPPKTDAMEQRFWDSIGKLAPLSPRFVSVTYGAGG
STRERTLRMVRRITTDTGVPAAAHLTCVGATRDEVNEVVRGYAEAGVNKIVALRGDPPEG
VGQPFTPHPDGYQNAADLVAGIRRLGNFDISVAAYPEKHPQSADWDADIDNLKRKIDAGA
DRAITQMFFSNTDFLRYLDRARKAGITAPIVPGIQPIHSFKQISGFAARCGASIPDWLAE
RFEGLEEDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRT
>A0A087RQ80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marine Group I thaumarchaeote SCGC AAA799-D11|TrEMBL
MTIRYEANPPKILPDVDTDQSIKKFIERIKNISKKCDAIHLTENVLGFQRVSPLEVGKII
KEEIPDLPITVSLRVRDKSEEEIFEFAEKCVEIGFAGILVLMGDPSQTGKADSGQIPSLT
VKKLREKNVDSKINLYLSVSNKPNFAKLAKKKDARPKGFMTQVVQNTEQVQALSDNLKEF
SIIPIILFPSQKNEKSAKFLGLDLESYSKEFEELLRKSHEITGDVLLTSPNDFTGLNEFL
GKTTF
>A0A6I9HRV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geospiza fortis|TrEMBL
MLGLGIGFFNHLLLTPAVPALCRHPCTDCPLCAPLCRAPTMVNETQHSCSASSSSRSDGG
SSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDKWFSLEFFPPRTANAAVNLIS
RFDHMGAGGPLFIDVTWHPAGDPGSDKETSSMIIAYTAVNYCGLETILHMTCCNQSKDDI
TGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDICVAGYP
KGHPEAESYEADLRHLKEKVYAGADFIITQLFFRPETFLKFMKDCQAIGITCPIIPGIFP
IQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGL
HFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRT
QEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFTCY
ITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGILTINSQPNINGKPSTDPIV
GWGPSGGYVFQKAYLEFFTSSEIVRALLKVLRKYELRVNYHIVNVKGENITNAPDLQPNA
VTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYL
VNLVDNDFPLENCLWQVVEDTFELLNSPPQQ
>C7GU28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain JAY291)|TrEMBL
MSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKT
LALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVE
AGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
AILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETVANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWET
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKA
WRDEAFSIWSEWAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETDELWEMLLDQA
>A0A2P5NTP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystis sp|TrEMBL
MFNALHPTASGKRFNISYEFFPPKTPEMETQLWETVKRLKALNPHFVSVTYGAGGSTRER
THAIVSRIARETQMKPAAHLTCVSSSKEEIDDILEGYWEAGVRHIVALRGDPPTGVGTKF
EANPTGYAKSCDLVRGIRRLHDFEISVSTYPEGHPESGSIEQDLDALEAKIDAGATRAIT
QFFFDNDIYFKFLDKARARGVTIPIVPGIMPIRNFRQVSSFATKAGASVPRWVAERFEGL
DDDPETRALVAATTAVEQVMGLARAGVDQFHFYTNNRADMVFAICHLLGVRPLREKVDA
>A0A4Q0Y036|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halarcobacter anaerophilus|TrEMBL
MLTDKIRNREKGILLYGITPPKANNTEEKIKEIAQKHIERISKLDVDGLVLYDIQDESDR
TNEKRPFPFIKTMNPCEYSKNYLQELKTPRIVYRAVGNYTAKRFKEWLKETRPTQVHSVF
VGAASYEQKNPLSLKEAYKLKREVNDNLCLGGIAIPERHTKKGDEHLRVFSKIDDSCEYF
ITQCIYDLEAAKIFLTDYAKYAKEHNYEMVPIILTLTPCGSSKTLDFMKWLGINIPNYLE
EDLKESGDILDASIKLSRDIFEELYSFGLKRGIPIGCNIESVAIRKAEIDASVKLLDEIK
AIIKKYS
>A0A0M8T8F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MMG1522|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PEALKERILAAKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>F8TES0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium ragsdalei|TrEMBL
MSLLKEAFEKGEFAVTAEMAPPKGTDLSHLIECAKKIKGRVHGVNVTDFQSATLKATSLA
TCKVLKDAGLEPVFQITGRDRNRIAIQGELLSAGVFEIENVLALTGDYTATGDHPGAKPV
YDLDSVGILQVASILNGGKDMGGTDLKGKPDFFLGACVTPRYDPLELQVIKMKKKIKAGA
KFFQTQAVYDMETLKKFKEETKAQGVDAKVMVGIIPLKSAGMAKYMNKNVPGIFVPDELI
DRMKNAEDKVQEGIKIAGEFIKAVKESGLCDGVHIMAIGAEENVPLILDEAGL
>A0A560EN26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirillum amazonense|TrEMBL
MTIVTETAADSPLGGGEPLVTVPRDLRVSFEFFPPKTEKMEQTLWQAIRRLAPLSPAFVS
VTYGAGGSTRERTHATVTAIQRQTGIPAAAHLTCVAATKEEIDAIARAYWDAGIRHIVAL
RGDPPQAADGSGGLGGSGYQPHPGGYAYATDLVAGLKRVADFEISVACFPETHPEAASAA
ADIDNLRRKVDAGATRAISQFFFDTDRFLRFRDTVAAAGIDIPIVPGILPITNFGRAVEL
GAKCNCAVPAWMEDLFGGLDAEPETRQLVAATVAVQQCLRLEREGVRDFHFYTLNRADLT
VAICHMLGVRAPKAP
>I0S8E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis SK616|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERLYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A8B9CNS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anser brachyrhynchus|TrEMBL
AVPAPQGCGSPSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDRWFSLE
FFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLE
TILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVKHIR
NEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFLKFMKDC
QAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAV
SMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVEDVR
PIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGE
ELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTIN
SQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNYHIVNV
KGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEES
PSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPQPEPSEVLR
>A0A8J7ITM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lusitaniella coriacea LEGE 07157|TrEMBL
MTNRFRRAVQAQDFLITAEVMPPKGGNPIRMVEMAKILKGRVHAVNITDGSRAVLRMSSL
AASVLLLQEGIEPICQMACRDRNAIGLQADLMGASALGIRNILALTGDPVKAGDHKTAKA
VFDLESVRLLQTIGKLNQGLDFNARSLPDEPTDLFAGAAVDPQLKSWSGLQRRFERKLAA
GAQFFQSQLIVDFERLDKFMTQIASGTNKPILAGIFLLKSAKNADFINRCVPGVEIPQTI
IDRLAAAENPLQEGMEIAAEQVRMAKQLCQGVHMMAVKREDLIPQILDMADITPIDPVWS
>A0A1H8D0V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stigmatella aurantiaca|TrEMBL
MKIRNRLNPSNPCFSFEFFPPKTDEGTENLLKTVEELAPLEPGFVSVTYGAGGSTRDKTL
GLVTRIKQTTGIEAMAHLTCVGHTREELRDVLQQLETAKLDNVLVLRGDPPRGQTAFEPT
PGGFRYASELVEFIREEDFNFCVGGACYPEGHVETESRDDDLQHLKAKVDAGLDFIITQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNVEQVQRFTRMCGATVPMRLGLQLDRVKD
QPDAVVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMILGALRSRS
>A0A4Y4DXM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulosimicrobium cellulans|TrEMBL
MPDGGRARTHPGRGDVVSVADAVGRAHGGAARPTVSFELMPPRRPDAAPKFWETARQLVA
THPDFVSVTYGAAGTDRATARQVVGRLLQGTPVLPIAHLTCVGASREDVEEVINDFLDEG
VRSFLALRGDPPRDQPDWQPAPDGVRSSTELVALLREVEASRCAADPAAALRGAARPLTI
AVATFCDGNPAAGTTRTQEVRRLWQKQQAGASFAITQLFYDASSYTDFVAEARAAGVTIP
ILAGLLPTTEPARLRRVEELTGVRAPQHLLDALDALPDPEAQHAYGVAYTVDLAQRVLDA
GAPGLHVYTFNKHRAALDLLEGVHLGGGSRGTGGSASAAAAPLVPDLASGPWVTGTSLPT
TSAATHGTPV
>A0A1E3IE70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus depauperatus CBS 7841|TrEMBL
MKITEKLQKAEKEGRPFWSFEFFPPRTAQASWMGLQNLYDRIERMRNLGPEFIDITWGAG
GKNADLTNSLVQVCQATIGIETCMHLCCTEMPKENVEWALKQAKAHGCQNILALRGDPVA
GTTTWEPTPGGFMRAVDLVRYIHEHYPNDFCVAVAGFPQGHPETPDADEGREQEMQWLKE
KVDAGADFIFTQMFYDTTIFFDWVRRVRQAGIMVPIIPGIMPIQSWEKFDRWVQREKIIV
PPHFYEALDPVKGDDEKVRQVGTKLVGDMCRTILGSKEAGIKGLHIYTLNLEKGARMLLH
ELGFEGRREQIVPLPWRPSLTPGRRSESIRPIFWTNRPLSYISRTSEWDEFPNGRWGDSR
SPAFGDLDGYPVSIGINPIDAYKLWGHPTTETELFDLFTRFCRGDLLKLPWSSQPPSPET
MVITEQLAKMNELGYLTINSQPAVDGVRSEDKVHGWGPAGGYAYLEFFVSPELLSPLLKR
IERDPRITYFAVNKHGDLMTNTHSEGPNAVTWGVFAGKEIPTIVDAVSFIAWKDEAYELG
LQWANLYPAASPARDLLTRVMNSFYLVNIVANDFKDGLSIFEPFLLNQTPIGKVVEGMKS
VAVGVKDAIGGQ
>A0A1R3RYT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus carbonarius (strain ITEM 5010)|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLGKVDAALQAAYKAGCTNILALRGDPPREKEA
WEATDGGFRYAKDLVQYIRSKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGASF
VITQMFYDTDNFIDWVKKCRDRGISVPIIPGIMPIQTYAAFIRRSNWTKVRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
IQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSIRDLTHIFVSFLEGKLARLPWSDTPITTEANAIKESLVE
LNKKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLLDELIARIDKNG
DLTYHAISKTSELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGEDWA
KCHEASSPSRKLIQGVMDSWYLVNIVNNDFHNTSNLFDLFKDLDVQDLDTEIPVENGEPK
THTNGAANGTINGVLNGTVPETAVKN
>A0A0D7QH81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. LTSPM299|TrEMBL
MTETVSPVSNGHRAPRTPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTITRILRETDLLPAAHLTCVGAARGEIDEIVDRYHEVGVRHIVALRGDPPGGI
GTAYATHPDGYQSSAELVAGIRKRHSDIEVSVSAYPEKHPEAADFDVDIDLLKAKVDAGA
TRAITQVFFDNDLYYHYLDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFDGLDNDAETRKLVAATVAAGQVQKLFKRGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A1Y3UG61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. An7|TrEMBL
MRVDQIFHEAKAAGRAPVSFEMFPPKGELTLERAHTAAEALSACGPDFISVTCSAGGTGN
SSATAQIAAMISHDFGVSAVAHLTGIGLTRGDLAERIEAYRAAGVENVLALRGDRPQGAA
LPEGDFSYAAEIIPALAEAGFCVGAAAYPEGHIECDDLAESIRHLRLKQDAGASFFVTQL
CFDNETIYRFLDLAERAGITAPITIGIMPFMGKQQITRTVFLCGTSLPSPVIKILARYED
DPESLMAAGIDYARRQLEDLAAHGVDGCHIYTMNRPSVARAAMAALRGDAA
>F5RR53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter hormaechei ATCC 49162|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMFAADLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A1G0M1E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium GWC2_58_44|TrEMBL
MAAEKTQLHNRIESGKQLLLAESSPPKGADPAALRDLARTLAGKVHALGVSDNRDGVHMS
ALAAAALIGAEGIEPIVHMTTRDRNRIALASDCLGAQAMGIRNLLCTTGTHQTLGPCRSA
KNVFDVDSIQLLGICNSLGVDASPLGEDSFEGAGPLCLGSTASPFADPREMQVIRLAKAV
AAGSRFVITQPVFDLERFALWWEEVTKRGLHEKVAIIAGIRPLADADHALAYAAKRPSPM
IPAAALERISAAGDKKGQRAAGIEIAVETVQRLAGLKGLRGFELRVDGEVDIAMELLEKS
GLRID
>A0A6G4XM94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces mesophilus|TrEMBL
MALGTASTRMDRARTVREMLATGKTTYSFEFSAPKTEKGQRNLWTSLRRVEAVAPDFVSV
TYGAGGSTRAGTVTETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPMAEWVKHPRGLTYASELVRLIKESGDFCVGVAAFPAMHPRSPDWDADVRNFVD
KCRAGADYAITQMFFHPEEYLRLRDRVEAAGCETPIIPEIMPVTSVRMLERLPQLSNAEI
PAGLKERILTSKEDAAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQA
>K9AQ69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus massiliensis S46|TrEMBL
MTLLKKLESNILVADGAMGTILYSEGLDTCPEAYNLSHPDKIEKIHRSYIESGADIIQTN
TYGANFEKLKAFGLEHKVKDIHVKAVEIAKRAARDDTYILGTVGGFRSVRQTELSLEAIR
YHAEIQIDTLVNAGVDGLLFETYYDLEELLQVIQDTRKKYEIPIIAQLTASNIHYLKDGT
ELNEAFEQLIEGGADVVGLNCHHGPHHMLKAYAHLKLPKQAYLSCYPNASLLDLQDQALT
YSDNATYFGDVARSLIEEGVRIIGGCCGTTPEHIQKIKQSVKDMKPITDKRVVPLKQPSR
QTRQTEAKENLTTAVKKRKSIIVELDTPRHLDTTKFFENVEKLDNERIDAITLADNSLAN
VRISNFAAASLIKQRYNLEPLVHITCRDRNLIGLQSHLLGLSMIGVNEILTITGDPSKIG
HLPGATNVYDVNSKGLAELAIRFNQGINTDGADLKGATHFNIAGAFDPNVRNIQGSVKRL
EKKIESGMNYFITQPVFSSEKIIEIYEATKHLETPFFIGIMPITSYKNAVFLHNEVPGIK
LEADVLQSFEAIKDDPEQTRALSIKLCKSLIHTVHQYFNGLYLITPFERVDYSIELAQYF
KSLSSKEEVIL
>A0A5L8RMT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter lari|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>L5NAM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacillus sp. BAB-2008|TrEMBL
MNLREALQNKTLIGDGAMGTLLYSYGIDRCFEELNLSHSEEVLNVHRAYVNAGADVIQTN
TYGANYIKLTRYGLQEQVKEINTAAVRLAKQAAHEGTYVVGTIGGIRGVQKQSFSLEEIK
RSFREQLYCLLFEEVDGLLLETYYDLEELKAVLEIARKETDLPIIAQVSMHEAGVLQEGT
SLSDALQQLEQQGADIIGVNCRLGPYHMIQSLEDVPLPDKAVLSAYPNASLPAFQDGRLV
YATDPNYFEKSAKSLYQQGARLIGGCCGTTPEHIEAIAAAVKGKEPIRKKEVPVKQGNGV
SLSSPEKNLEHLHERAKRGRSIIVELDPPKKLNTDKFLEGAKALQDAGVDSITLADNSLA
SPRISNDTMASIIKTKYGVDPLVHIACRDRNLIGLQSHLMGLHTLGIQQLLAVTGDPTKI
GDFPGATSVYDLSSFDLIHYIKQLNKGISFSGKSLGERTSFSVAAAFNPNVRNLNRAVGR
MEKKMKYGADYFISQPVFNHEQIVEVYEATKHIEAPIYIGIMPLTSARNAEFLHNEVPGI
QLSPEILARMEQAGTDKTQAQAEGISIAKSLIDTAMDLFNGIYLITPFLRYEMTVELTNY
IKEKTAQRERKVTDGIHLV
>Q0VL81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2)|TrEMBL
MKRISFEFFPPKTDQGKEKLLATQQKLLVKNPAFFSCTFGAGGSTRDNTRDTVNKLREQH
GDTAPHLSCIGQSREEILELVNGYKEAGVQRIVALRGDLPSGMGYAQSEIKYADELVQLI
RQETGDHFTLEVAAYPEMHPQARSFEDDIAHFKRKVDAGANSGLTQYFYNADAYGYYMDA
LQKIDCDAPVYPGIMPILNVANLLRFSNTCGADVPRWLQSKLNDIKDDDAAVKAFGEEVV
TRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGM
>A0A3S0TTE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp|TrEMBL
MAQERKSKLLGSGDILVSFEFFPPKTEKMEETLWSSITRLAPLGPEFVSVTYGAGGSTRE
RTHATVTRLIKETPLKPAAHLTCVDATKEEVDAVAKTYWEEGVRHIVALRGDPAQGTGAK
YVPFPGGYKNAADLVAGLKRIADFEISVAGYPETHPESLSIEADLDNLKAKVDAGADRII
TQFGFDNVHFLRFLERARAAGIWVPISPGIVPIHNFKQVAGFAKRAGASVPSWLARRFEG
LEDDSATSHLVGAAVATEQVMDLVDEGIKKFHFYTLNRADLVYAICHLLGLRSVRPANAD
AA
>A0A0D6SXM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FeS53a|TrEMBL
MSQDRRYSFEFFPAKTEAGHEKLLATARTFAGYKPDFFSCTYGAGGSTRDRTLQTVLQLD
GEIQVPTAPHLSCVGDSKAELRALLAHYKDAGIQRIVALRGDLPSGMGMASGELRHANDL
VEFIRAETGDHFHIEVAAYPEVHPQARNFEEDLKHFVNKVKAGADSAITQYFFNADSYFY
FVDRVRQQGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYADDTASIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>G3A3E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia syzygii R24|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILNTYRENGIRRIVALRGDLPSGMGEIGEFRFANELVEF
IRHETNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLLRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>A0A433A8M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp|TrEMBL
MAQNTEKKSKLLGSGDIVVSFEFFPPKTEKMEETLWSAISRLAPLRPEFVSVTYGAGGST
RERTHATVTRLLKETELKPAAHLTCVDATKDEVNAVARQYWNEGVRHIVALRGDPANGAG
AKYEPHPDGYKNAADLVAGLKKIGDFEISVAGYPEKHPESQTAEADLDNLKAKVDAGADR
IITQFGFDNAHFLRYLERARAAGIWVPISPGIVPIHNFKQVAGFAKRAGASVPSWLARRF
EGLEDDSATSHLVAAAVATEQVMDLVDEGIKKFHFYTLNRADLVYAICHLLGLRAARAAN
ANAA
>A0A674ANE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmo trutta|TrEMBL
MVNNVQRVDDNWRTCTKSDSSGKRNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKETITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRTDT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLKQLVKLSKLEVPEEIMQVIEPIKDNDAAIR
NYGIEQTVGMCRVLLESGNVLGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMMDKLDKVN
RRGVLTINSQPTINGMPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDNMFELLDNPPEEQPTEQP
AEQPAEESPVEDQPTK
>A0A845M3T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidaminobacter sp|TrEMBL
MLHHIENRIYHVEILPPKQDTEKLTADLALFADKYNKALEIGSCICLTDNAMGNLAFQGT
EVIEELELPVKSDQVMIHLNTFHTLEDLKNILNKCKALGIKYLLVISGDGSDRLPKLQAA
DLNLTDTTTVTSVELLSYIHREYPNEFILGVAFNPYEPAEHEFHKLERKLKAGAAFIVTQ
PVIESNEIINQLLNLYPAIPVVIEAWMSKKLHLLSEAVGYEIPENTEFDPIETLKMLHKI
YPNCGVYLSLLSFKTQFDLLSETWI
>A0A174YQ86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospira eligens|TrEMBL
MKYTGTAGILYDRLKSEILVADGAFGTYYAKKYDTGSLPELANLQASDRVLAIHKEYIEA
GAKIIRTNTFASNTVCLGAGFDEVRNNIKNAVDIAREAVKGTDVLVAADIGPIPGENMIE
KEHIEKEYVDIVNVFKECGVDIFVFETFPELGFIDKAIENAGENGFVITQFAINQFGYSS
AGFSARKLIEEAEKNSYIDACGFNCGVGPGHMKKLVQSLINRNDKYFAVLPNAGYPQVVS
GRMVFDDNNAAYFSQIMHDLAEDGADIIGGCCGTTPEYIRQMVLKTADVVHKKNASIEEE
ITEKKTANDVSFYKGKEGRKLIAVELAPPLGIDDEKIMDAAFLMKESGVDVLTFPDSPSG
RTRADSILMAEKVSRETGMCVMPHICCRDKNAIAMRSQLLGAHINDINNFLVITGDPIPS
VVRASVKSVFNFDSVGLMNIISDMNQEQFAGEPVIYGGAINQGRVNFKVELERVKKKMEA
GATFFMTQPVFSDEDIDRLRQIKEQTGARILCGIMPFVSLRNATFMKNEMTGINVTDEIL
SRYRADMSKEEGEETGIQIAREIIAKTTDFVDGYYFSFPFNRVHMLKKIIGKNNQ
>A0A7Y7ZYM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. IPO3779|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYHPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNAESYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A075HTC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured marine thaumarchaeote KM3_85_C11|TrEMBL
MIYRSKVLIMYNQKPPMTVRYEINPPKISDDGQDVRNVLFERIETISSVCNGIHLTDSVL
GIPRVSPFEIAKQIRESNKNIKLTCSLRVRDKNLNDIEKIVQESIGTVDGILVLMGDKSD
TMPNKDNLIPSQVVKALNDNGLDKKIELFLSIPSNPNFAKIQKKIDAKPTGFVTQVIHSK
DQVEKIVNYLRPNGFKIIPCLLLPSKNNLKSAEFLKIDWSNYKENIIEFINEIHSIDSEI
LVTSPNDFKRAHETLTKLAT
>A0A7R7WYH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus kawachii|TrEMBL
MTRMMLAAMGSAVRHGAFSGGSIGGRKSCSSPPPSFTPSSFLAFHSLSSVRHRVAVSAAE
TALIMEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGA
GGSTAARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPP
RSEEYNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDVQDPARD
LPYLIEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILT
RVTKLSHVKIPPQVLSKLEEVKHDDDAVKRIGVDIITDLVYGIRDLVSPGLRGFHFYTLN
LEKTVSFILERCELIPPYTEIDDSDALVDGGNLSAMDSSSYIAPNGAPIRTLASRRSSVS
SIPHNRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATW
DDFPNGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHM
VPWSEGGAEEDSNGLNAETAVIQPELLTLIDKKGWWTLASQPALNGVRSDDPVFGWGPPG
EGFVFQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNPDDPDP
IDINPANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFL
DETKNDVWLVCVVGQEFGAGTEAGSEEEEDEKKWMWRELANSQ
>A0A7S2JL28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haptolina brevifila|TrEMBL
MGIHDVLVTGSPPNTPPPASGSGKFASATELVSFVKERMGDAMRVAVCGYPRGSRGERGE
YAADLAEVGRQVLAGAERVVCLPCFDAETHWSFVADARAARISCPIAPGLLPIYSAAEFR
HVCRALAVDPPAWLEAKLRAAAGTKEVAALGESLLVQQLEALNSSRACTPHIYTLNSEAI
LQPLALAGYKPLKHRA
>A0A849VY92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium luteolum|TrEMBL
MSTISASAPLDACSPATAPEAGVPAGTSGTRLALSFEAMPPRSAAQQQRSGALLELLASY
DPDYLAVTSAVGTGWSAGTAAFIEQLAATTRLRPLAHLTCTAAPRRELTEWIERFIDAGV
RGFLAVRGDLAAGQSAPPRGHLAHADALVALLREVERGHVARLCGGRLAIGVAAYPSGHP
ESRHPAEDIDVLAAKQRNGADFAITQLFFDPALITAVADRARLAGVTLPIIPGIMPITGT
ARLQRMCRLSGLTPPPRISQALAAARSPAEEYDIGLDLTADFVDELIAAGVPGLHFYTFN
DPTTITELLSRLRPATLARLTADRKDLP
>A0A146FRI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus kawachii|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDVQDPARDLPYL
IEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPQVLSKLEEVKHDDDAVKRIGVDIITDLVYGIRDLVSPGLRGFHFYTLNLEKT
VSFILERCELIPPYTEIDDSDALVDGGNLSAMDSSSYIAPNGAPIRTLASRRSSVSSIPH
NRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEEDSNGLNAETAVIQPELLTLIDKKGWWTLASQPALNGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNPDDPDPIDIN
PANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDETK
NDVWLVCVVGQEFGAGTEAGSEEEEDEKKWMWRELANSQ
>A0A261R787|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella genomosp. 9|TrEMBL
MTDTTTPAYSLEFFPPRDIAAQERLLRAAKQMLAIHPRYVSVTFGAGGSTREGTAGTVRT
LRNLGVDAAPHLSCVGATQADLRAILASYREEGVRQVVALRGDLPSGMGGDAGELKYARD
LVAFIRKETGDWFHIEVAAYPEMHPQADNPSRDLDHFVDKVRAGADSAITQYFFNPDAYF
DFVERVAAKGVSVPIVPGIMPITNHTQLARFSQMCGAEIPRWIRLRLAEFGDDKASIRSF
GVDVVTDLCRKLLDGGAPGLHFYTLNSAEAPMAIWKNLTSQA
>A0A269YYL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei|TrEMBL
QRFNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKVGHLPGATNVYDVNS
KGLTEIALR
>A0A074J4B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioclava pacifica DSM 10166|TrEMBL
MTTPKVSFEFFPPQTLDASFRLWETAQVLAPLQPEFVSVTYGAGGTTRKLTHEAVGTIHK
NYGLNVAAHLTCVEATRAETMEIVNSYAEVGVTEIVALRGDPPKGAKGFVPHPEGFASSV
ELIEALAEDGRFTIRAGAYPEPHPEAADPLADVRWLKRKVEAGATSAITQFFFEAETFFR
FRDACEREGITAKIIPGILPIQSWKGAKNFAQRCGTSIPAWVEEAFEAAVRDGREQLLAT
ALCTELCDKLIEGGVEDLHFYTLNRPGLTRDVCHALGVTPEAVLENVA
>A0A0A2I1U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp. Tol-SR|TrEMBL
MKAGSNLEKVLAAGHFAVTAECGPPRGADPEIVRKKAAYVKGNVDACNVTDNQTSVVRMS
SVAGCMLLKEMGIEPLLQMVVRDRNRIALQSDLLGASALGVRNMLCLSGDHQKFGDDPQA
KNVFDIDSMQLIHLVKTMRDEGTFPSGQKLDGAPKFFIGCAVNPFADPFEIRVPRLKMKM
MAGADFVQTQCIYNLDKFKVYLEDAKRQGLHEKVKILAGVTPLKSAGMAKFMKKMVAGMD
IPDAVIKRIADEPKEKQSAKGIEMCIELIHQLKEMEGIAGVHVMAIEWEEKLQEIIGGAG
LLPRPVVD
>A0A7C9K818|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas alkaliphila|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAARQPRFFSVTYGAGGSTQARTRDIVR
TVSQCGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVEKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAF
GTDVVSRLCERLLDGGAPGLHFYTLNQAAPVLKIVDNIGG
>A0A5R9LUP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. So13.3|TrEMBL
MSTLREILASGTRSFSFEFFPPKTDAGERSLWESIRRIEAVAPTFVSVTYGAGGSSRSRT
IAVTQRIAAQTSLRPVAHLTAVGHSVGELRRIIGQYADAGVRDVLVLRGDPPGDPRGAWV
PHPDGLNHARELVTLVKGSGNFSIGVAAFPERHPRSPDWETEVRHFVAKARAGADYAITQ
MFFRAEDYFRLRDRVAAAGCDLPIIPEIMPATDVRQIRRFAELSNATFPDDLAAQLAAAE
HDPDVAHRIGVDHATRLAQRLLDAGAPGLHYITLNRSTAALDIHRNIRSADAVPHRR
>W6S099|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium bornimense|TrEMBL
MIKDYLKDKILVTDGAMGTYYMRDKVNAVPCCELANILNPEEIKKIHMEYIEAGAKLIRT
NTFAANREALDVTDEELKKIIVNGYKIAKDAAKGKEVFVAASIGPIRTNVEKDVDIFSEY
KYIVDNFLEVGADIFVFETFSKLDYLDKISTYIKGKNKDAFIITNFAIMGDGFTRDGVSL
NKIISEIKTYKSVDIYGFNCGSGPTHLYKLLKEIDIKDDIVAVLPNTGYPEVINERTIYP
NNPEYFGYKMMDFKRLGFRILGGCCGTSPEHIKKIVEALNRNDKLEIKRYKQEEGNNNIT
LKKENKFLGKLKENKFVLAVELAPPFDTSIDKMMHCAKVCKDNNIDLVTIPDSPMSKVRV
DSIILATKIKREIGIDAMPHICCRDKNTNAIRSGLMGAHIEDIRNVLALTGDPMSDINKL
ETKSVFNLNSFKLINLISEMNEEVFTDDNIAIGGALNLNVRNKDIEVSRMKKKIERGANF
FLTQPIYDDETFEYLKKVKEENNVKILGGILPIVSYKNAQFLNNELPGVHIPEKYLNRFT
LDMDKEEAEKVGIEIAVELGNKMKDIVDGFYFITPFKRVEMIIKIIDRII
>A0A7G9QR28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomonas brevis|TrEMBL
MLPISFEFYPPKTDEQHAQFDRTVRKLKAYAPQFMSVTFGAGGSTLSHTPETVQRLRGEH
GVTGVPHLTCVGGSREEIRTLLKLYRALGCDRIVALRGDLPSGMARSGDLRYANELVQLI
RDEHGDHFHIEVAAYPETHPQADDAQADLRHFKAKVDAGASGAITQYFYNADAYFRFVED
ARALGIDAPIVPGVMPIANFSQLRRFSEACGAEIPRWIAKRMQAHGDDAEAVREFAADVV
AGLCRRLIDGGAPALHFYTLNLAKPTQSILQRL
>A0A6L8T4D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia wexlerae|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKV
>E4Q2R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldicellulosiruptor owensensis (strain ATCC 700167 / DSM 13100 / OL)|TrEMBL
MKKSFREFLKEQSIIIFDGAMGTELLNRGFSVDFPLEWANIANPELVKQIYRDYILAGAQ
CIETNTFGANECKLKIFGFENEVERINRSAVRIAKEMADDKVFVIGSVGPLGKPVGSGFE
IDATRAKEAYKRQLYFLLDEGVDAIIFETAASTHEVQIAIEALKELNDKIPYIIQFSFTR
ELTTIYGEDIYRVIEFLKFTDADVVGLNCGNGPQKTLEALKIFSQHLKGPFSVQPNAGYP
QMIQGRPVFSTPAEYFAWFAPEYVKLGAKIVGGCCGTTPEHIKAIKDKVKEFLHGIEVEV
VEREEKQEAVLKDTPSEFSQKLGKKFIFTVEISPPKGIELEKTKEGVKLLKEAGADTVNI
ADSPMARVRISPIALAHILKEELGMESILHFTCRDRNLISLQSELLGAAALGVKNVLALT
GDPPSIGDHPQAKPVFDVNSEGLVLILSRLNSGTDYMGNPIGKATNFTIGVALNLNADDL
EKEIERLKRKIENGAHFIETQPIYDAETLERFLEKVDFALPPILGGILPLRSSRHAEFLH
NEVPGITIPDKIRERMRSSKEPAKEGVEIACEIVEKIKHMVSGIYIMPPFEKYEMAVEII
KNFKY
>A0A1G8TDP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas titanicae|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARNPRFFSVTYGAGGSTQARTREVVR
AVGESGINTAPHLSCIGSEKAQLRDLLAQYREEGVESLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLEGGAPGLHFYTLNQAAPVLKIVDNLTD
>A0A366DMF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudochrobactrum asaccharolyticum|TrEMBL
MDHVTSVHQQQGVIQLPCLPYTLEITGKAIGEIVAAQQVIPQGTAINIAFLGNENHAQRI
HAAKTIRDCGFEPVPIISSRRLLSVEDRDQLLSNLIKEAAPKRFLLVGGDPAQPAGPFQD
SLSLLNSKIVESFGIRHVAITGYPEGHPKIDQKELWRCLKWKLDYLRQAECSVEITTQFG
FDAQAIVRWIERLRSEGIDTPVRVGIPGPADAAKLLRFAKQFGVVASASIMRRYGLSLAN
LMRRSVADRYWEDLNALLLKQDLGQVYFHLYPFGGVAESVTWMNEQLRQRSS
>A0A2D8C8A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus sp|TrEMBL
MKITEHLKNAKSTLFSFEILPPLKGQSLKELLEGIAPLMDFKPPFVDVTYHREEFIYKKH
PNGLLEKISTKKRPGTVGICAAIMNRFQVDAVPHLLCGGFTREETENALIDLNFIGVENV
LALRGDAPKTEGRFVPENDGHHFASELVEQIIRMNQGKYLHEETETSFHTDFCVGVAGYP
EKHFEAPSMKFDLKYLKEKVEKGAEYIVTQMFFDNEKYFKFVEDVRAAGITVPIIPGIKP
ITTIGQITMLPRTFFLDLPDALMDELEKCKTNGEVKEVGIEWAIQQCKELVAADVPSLHF
YTMSKADATYKIAKEVF
>A0A558J0K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas titanicae|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARNPRFFSVTYGAGGSTQARTRQVVR
EVSESGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDNSEAIAAF
GTDVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKIVDNLTD
>A0A0Q9PRT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Soil766|TrEMBL
MLKNKILRRESGIITYGMTPPKETHSLEKMAEISQKQCERLQKLQIDGLILYDVQEESDR
IDQDRPFPYLQTVDPTTYSKTYLSKLNIPKIIYRCVGKYTEEQLAEWIQADLEEERFSVF
VGASSSKQEVQIGLPEAYELSRKLNDNLTLGAVVIPERHMKKDDEHLRMISKIASGSRFF
ISQATYNVEASKNFLSDYYYHCKENKLDMVPILMNIAPCGSTKTLEFMKWLGISIPKWLE
NDLKYSHDVLDKSVSVSQQIFEEIFEFGLEKGIPIGCSVESVSTRKVEIEASIQLVHEIK
AMMEKKMRSSFVF
>A0A2S1XKN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. TSH58|TrEMBL
MTSGTPSVSFEFFPPKTEKMEQSLWQAIQRLAPLGPSFVSVTYGAGGSTRERTHNTVTRI
QKETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPETEGGVGGRYVPHPG
GYAYAADLVAGMKKVADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQFFFY
NDAYFRFLDRCAAAGITVPIVPGILPITNFARAVEFAGKCGAAMPQRFAETFEGLDADPE
TRQLVAATMAAEQCQALQAQGIRDFHFYTLNRSELTLAICRMLGVKAKQPAVS
>A0A1X7KC89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenibacter troitsensis|TrEMBL
MFRGINKIIANGPFLWKRLEGEIMKVTEHIKKAEGKTLFSFEIIPPVKGRSIQELYDNID
PLMEFKPPFIDVTTSREEYVYIDRNGLLDKKLTRMRPGTVGICASIQHKYGVDTVPHVLC
GGFTKEETEYVLVDCQYLGIQNVMALRGDARKEEQYFNPTKGGHAYASDLVKQIYALNQG
NYLHDKVETVHSADFCIGVAGYPEKHLEAPSLITDLKRLQEKVEAGADYVVTQMFFDNQK
FFEFVEAAKKMGINVPIIPGIKPIAVKRHLQLLPQVFKIDLPQDLIDAVEGCSTNADVRQ
VGIEWAIQQSKELKAAGVPVLHYYSMGKSDNIEAIAKELF
>A0A2V9H2E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRPHEHRRQPHGTKALSAAASWSRQDNGTVKIYDFNERLKDAILIADGAMGSMLHEAVGF
ERCFDELNSTEPEAVFRIHQAYIEAGAQIIETNTFGANRFKLAPLGLAEEVQRFNSRGVK
IAREAREAAAREVLIAGSIGPLGLGVQSRHPSPEEIQEIFHEQALALEERGVDFYILETF
SYIEELLLAIDAIRSFSGLPIVAQLTYAEEGTTYGDVRPADAAAQLKNKNVQVIGANCTL
GPQALLPILEELAAVDGLRVSGMPNAGFPKREGDRIVYPRSSPEYFALFAREAAALGVRI
LGGCCGTTPAHVRAMAEAVKLLRPSKTHPVVRSVETVLRPAPVAHREPESRFWKQLQKKE
FSVCLEIDPPKGLSLERIFEQVDKVMASKKVDAIDINSGAMARVGMDALIVAGALEARGI
ETVPHLTTRDQNIIGLQAALLGAWTVGGVRNVLAITGDPPSVGDYPETSGVYEVDSVGLV
KVLNRLNQGTDWAGKTLGGRTNFTIGVAVNPVADDLDNEIERFHAKVEAGAHFAMTQPLF
DPEHWNAFLKKLGGKPVIPVLIGIWPLTSYKQALRLSNEVPGIVIPEPLLKSMEAAGSAA
RDRGFEVARHMLAWARTELAGAYLIPPFKRYEEILEIL
>A0A2V8RQ16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MFIMDDFREILASDQITVFDGAMGTMLYSKGIYINRSYDELNLTNPDLVREVHEEYVRAG
AEVLETNTFGATTHNLQQYGLDARLREINIAAARLAREAAGTRAYVAGAIGPLSLRIEPY
GPTSFDEAKEMFKAQAEALVEGGVDLFVLETFSDISEIRQAIRAVRELCDLPIITQMTIQ
MDGNTSYGTTPEVFTARLDEWGADVIGLNCGVGPAIVLNAIEKMRDVTNKKLSAQPNAGL
PRDVQGRQFYMCSPEYMAKYAKRLIQAGVKFVGGCCGTTPAHIKLIAGAVRAVSPRRQRV
SFHAPQPARGEELTPADIRVVPLEERSNWARMITRGEFVTTVEVLPPKGCAPEKTLESIR
LLKDAGVNAVNIPDGPRAQTRMGAQATALLVEREIGLETVLHYCCRDRNLLGMMSDLLGA
AALGLRNLLLITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGCPTSFC
IGVGVNPGAINLDEEIKRFEYKVEAGAEFAITQPVFDVEQLRTFLSRIEHVRIPVVAGIW
PLVSYRNAEFLHNEVPGVRVTPEIMERMRVASDKGKEFGREEGLQIARESLVEVRDLIQG
VQVSAPFNNVRYALEVFEALPEFAARKESVAS
>A0A2V8X9E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIHDFNERLKDSILIADGAMGSMLHEVVGPQRCFDELNTTEPEAVFRVHQAYIEAGAQI
IETNTFGANRFKLMPLGLGDEVQRLNSRGVKIAREARESAAREVLIAGSIGPLGLGVQSR
HPADDEILDIFHEQALALEERGVDFYILETFSYIEELLLAIDAIRSFSGLPIVAELTYAE
EGTTYGDVRPSHAAGQLKNKNVQVIGANCTLGPQALLPILQELAAVDDIRVSAMPNAGFP
KREGDRIVYPRSSPEYFALFAREAAALGVRILGGCCGTTPAHIRAMAEAVKLLHPAKSHA
VASPVEAVSKPAPVTQREPESQFWKNLKTKKFTVCVEIDPPKGLSLDRIFEQVDKVMASK
KVDAIDINSGAMARVGMDALIVAGALEARGVETVPHLTTRDQNIIGLQAALLGAWTVGGV
RNILAITGDPPSVGDYPETSGVYEVDSVGLVKVLHRLNQGTDWAGKTLGGATNFTIGVAL
NPVADDLDNEIDRFHAKVEAGAHFAMTQPLFDPEHWHAFLEKLGGKPSIPVLIGIWPLNS
YKQALRL
>A0A8F6BV88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum sp. AHE14PA|TrEMBL
MKVTEHIKKANGKTLFSFEIIPPKKGNNIQDLYNNIDPLMEFNPPFIDVTTSREQHLYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIEN
VMALRGDAMSHQRYFEASKNGHQYAIELVNQIENLNKGKYLHEVIEANHKADFCIGVAGY
PEKHLESPSLQTDLKRLREKVDAGADYVVTQMFFNNQKYFEFVNAAREIGITVPIIPGIK
PISVKRHLQLLPQVFKIDLPEILINSLDNCKSNKEVRQVGVEWCIEQSKELLEAGVPLLH
YYSMGKSDNIKAIAKALF
>A0A2V7XAA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MAADFLERLKQSPVLCDGAMGTLLYAKGIFINRSYDELNLSQPDLIRGIHHDYLQAGAEI
IETNTFGANSFRLARHSVADKVRDINRAGVRLAREAAKSFDVWVAGSVGPLGTRIEPLGK
TSYQEARDAFREQIQALVESGVDLLILETFGYLEEIHQAMLAARDVHPSITLVAQVTIDE
DGNCLDGSDPQTFTPKLAEWGADVIGCNCSVGPVAMLDAMERVRALTSLPLAAQPNAGIP
RSVDGRNIYLCSPEYMASYARKFVAAGVRLVGGCCGTTPDHIRVMKSALRVGEARGRIAA
ARSSTTQPAPPPIAAVPLEKRSPLGAKLAAGEFATMVEIVPPKGIDVSKEVEGARFLKSV
GVDGVNIPDSPRASARMSNQALSLLIQREVGIDAILHYTCRDRNVLCIQSDLLGAAAVGI
RNLICITGDPPKMGNYPDATAVFDVDAIGLVNIVHNLNRGLDLGGNSIGVGTGFVIGVGA
NPGLTDLDEEIRRFEFKVEAGAEYVVTQPVFDLRLLEVFLRRIEHCKIPLIAGIWPLVSV
RNAEFMKNELRVSVPDSILERMARAQNPEAARAEGVAIAREMLMACRQMTQGAQISAPMG
RYSSAVDVLEALGTEPAASR
>A0A7W1SGV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MGNNLGRGTFIVSVELVPPRGFRADEMLEQARQLRIHGVDLVNVPDGPRASGRMSALSAA
VLVQQHAGLETILHYTCRDRNLLGMQSDLLGAHSMGIRNVLIITGDPPQMGDYPDATAVF
DVDSIGLTNVVKRLNQGLDIGGQSLGQPTAFHIGVAANPGAPNIDEEIRRFEYKVEAGAE
FAITQPVFDAAELSRFLARIESVRIPVLAGVTPLDSLRHAEFMANEVPGVRVPEAVIERM
RRADGEGRAADEGLAIAREIAVEVRPLVQGIQITAAGGSLEPILALAGSTAA
>A0A2V9CKH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIADFEQRIEHAVLVADGAMGSMLFEGAGPQRCFEELNVSQPEAVFRVHQAYIEAGAQI
IETNTFGANRSKLTALGLRDQVAGMNHRGVKIAREAREAAPHEVLIAGSIGPLAIAPEMR
EVPREEMLEIYREQAQALEERGVDLFILETFSNIDMLMAAIDAVRAFSSLPIVAELTFSE
EGTTLDGTRPAEAAGRLAQKNVQVMGVNCRLGPQSLLTILEGYAEGHRPLSAMPNVGFPT
RIGDRTVYPRSSPEYFALFAREAAAMGARIVGGCCGTTPEHIRAMAGAVRGLRPAQAAKA
ASVTIATPPKKTRVVRRDPESGLWHKLKAREFAVSVEIDPPKGISLERIFEQVEKITTSG
CVDTIDINSGTLARVGMDALMLAGALQARGVETIPHVTTRDQNLIGLQAALLGAWSIGGV
RNFLAITGDPPSVGDHPESSGVYEIDSIGLVKVASRLNQGTDWAGKALGGATNYTVGVAV
NPTAEDLDYETQRFLAKVEAGAHFAMTQPLFDPEHWHVFLRRIGGRSPIPVLAGIWPLTS
YKQALRLNNEVPGIFIPESVLKEMQSAGTAARDRGFALARRMLAWARTELAGAYLIPPFK
RYEEILELLT
>A0A2V8WXG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIHDFNGRLKESILIADGAMGSMLHEAVGTQRCFDELNATEPEAVFRVHQAYIEAGAHI
IETNTFGANRFKLVPLGLGDEVQRLNSRGVKIAREARESAAREVLIAGSIGPLGLGVQSR
HPEPQEILDIFHEQALALEERGVDFYILETFSYIEELLIAIDAIRSFSGLPIIAQLTYSE
EGTTYGDVRPTDAAAQLKGKNVQVIGANCTLGPQALLPILQELTAVDDLRVSGMPNAGFP
KREGDRIVYPKSSPEYFALFAREAAALGVRILGGCCGTTPAHIRAMADAVKSLKPVTTHA
AAHSVEVLAKPAPVTHRDPESKFWKKLKASQFTVCVEIDPPKGLSLDRIFEQVDKVMASK
KVDAIDINSGAMARVGMDALVVAGALEARGVETVPHLTTRDQNIIGLQAALLGAWTVGGV
RNILAITGDPPSVGDYPEASGVYEVDSVGLVKVLNRLNQGTDWAGKTLGGATNFAIGVAV
NPVADDLDNEVERFHAKIEAGAHYAMTQPIFDPEHWHAFLKKLGGKPAIPILIGIWPLNS
YKQALRLNNEVPGIVIPASLLKSMESAGAAARDRGFEVARDMLAWARTELAGAYLIPPFK
RYEEILEIL
>A0A2V9Y045|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MASDLLAHLKTSPVLCDGAMGTLLYSKGIFINRCYDELNLSQPDLIRSIHHEYLQAGAEI
VETNTFGGNSFRLARHSLADRVRDINFTGARLAREAAKSFDLWVAGSVGPLGIRIEPLGK
TSYQEAHDAFREQIAALVEGGVDLLILETFGYLEELHQAILAARDVNPRIPVVAQVTIDE
DGNCLDGSDPETFTAKLEEWGADVIGCNCSVGPVAMLDAIERVHAVTSLPLAAQPNAGVP
RSVEGRNIYLCSPEYMASYARKFVAAGVRLVGGCCGSTPEHIRVMKAAMRVGGARSKTAA
AQVIGSQPPPPAAPAIPLEERSRLGAKIAAGEFVTMVEIVPPKGTDIRKEVEGARFLKSI
GVDGINIPDSPRASARMSNQALSLLIQKEVGIEAILHYTCRDRNVLCIQSDLLGAAATGI
RNLICITGDPPKMGNYPDATAVFDVDAIGLVNIVHNLNRGLDIGGNPIGHGTAFVIGVGA
NPGVPNIDEEIRRFEYKVEAGAEYAVTQPVFDLALMENFLNLIEHCRIPVIAGLWPLVSV
RNAEFMRNELRVSVPDSILERMGRAANPEAARAEGVAIAREMLVALRDMVQGAQISAPLG
RYTSAVDVLEALGSTSPANSV
>A0A7C2U9F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRIEDFNERLKDAILVADGAMGSMLYESQGPQRSFDELNLTEPEAVFRVHQAYIEAGAQV
IETNTFGANRLKLGLIGLGESAARINHRGVKLAREAREAAAREVLIAGSIGPLGASRQVR
PLPRDEICDIFREQAQALEERGVDLFVLETFSDIEELVAAIDAIRGFSRLPIIAELTFSE
EGTTFGGTRPADAWGRLKQKDVQAVGANCTLGPQALMPVLEEFTVLDAGFVSAMPNVGFP
KRVGDRVVYPKSSPEYFSLFARDAAALGVRIIGGCCGTTPEHIRAVAEAVKKLRPSRAAG
RAPGTAVLEAPVEVKRPATREPESKLWKKIRAGEFAVSVEIDPPKGVSLERIFEQVDRVV
ASGQVHAIDINSGTLARVGMDALMLAGALEARGVETIPHLTTRDLNIIGLQASLLGAWSV
GGVRNVLAITGDPPSLGDHPETSGVYEVDSIGLVKILTRLNQGMDWAGKTLGGATNFTIA
VALNPVADDVDEEVRRFVAKVEAGAHFAMTQPLFDPEHWHAFLKKIGGKCPIPVLVGVWP
LTSYKQALRLNNEVPGIVIPENVLKELDAAGTEARACGFRLARRMLDWAKTELAGAYLIP
PFKRYEEILEIFG
>A0A7V9ZN17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MIQAGAKFIGGCCGTTPAHIKLISDAVRAASPRKQHVVVSEAVAARVEELTPADIKVIPP
EERSLWSRKITNGEFVTSVEVLPPKGCAPEKTLESIRLLKDAGVDGVNIPDGPRAQTRMS
AQATAVLVERDIGIEAVLHYCCRDRNLLGMMSDLLG
>A0A0P1BCH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceraceosorus bombacis|TrEMBL
MAPSLSSPPAPLSPTQQQQQQQQDGKQEANTDWRITTKIAKAEREGRIWWSFEYFPPRTA
QGLTNLYDRIERMADLGPAFVDITWNAGGRTSDLTAQLVKTVHTYMGLETCMHLTCTNMP
RSKVDVALREAKQFGCRNILALRGDPPAGGGAWEKHEAGFEYAKELVQYIRQAYGDYFAI
AVAGFPEGHPESLEGKKMELERLKDKIDAGADFIFTQMFYDFDIFAQWVRDVRAAGITCP
IVPGVMPIQTYGGFQRATARFRTIVPQYFHDALEPVKDDDAKVREVGTQLVGDLCRRIID
PKEGLRISGLHIYTMNLERGSRMLLDYLALSPSPQQVKTLPWTPSLTPKRRDEGIRPIFW
ANRAKSYVDRTETWDEFPNGRWGDARSPAYGDVDAYGVKLRYSEAEARELWGEPTSLEQV
KQLFTGFCKGDIKALPWSETAIAKETTVINDKLVSMNQKGFFTINSQPSVDGARSDDPVH
GWGPKNGYVYQKAYLEFFVAPSQVDGLISKLEQDPQITYHVVNARGDMRTNTTSEAPCAV
TWGCFPHKEIIQPTIVESISFLAWKDEAYEIGRHWARVYPPGSQSRRLLESIFGNASGDV
TPGTSPDLHADQSWFLVNVVHNDFKNKEAVFAPFLDAADLSAAAVAAAAAAATTTASLEN
ATETARNVASGAENVAKSLAEKATAPLANGHVA
>A0A0B4CUH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hominis|TrEMBL
MSIVTSTPAALASRVAGCPKSMAYGPCGGVNADGTCEVHPTPCVFLARELPVRWTGAVAR
ATDPESGSGDPSTASTLAGRELVAIAARRPLVFTGFPVRALRADAVGATAEALLGSVDAV
LSGDAGRSRVQFPPSYRAALIGATGLRLWMGFNTRDRNRTALERELLSLRPLGVAGVHCV
TGDHTQTGDRPDARPVFDLESTTTLPRAAALGLLTSFAESPAAPPIAERGARVAEKQRAG
GGMCLTQYAGDAEEVAAFVALCRAAGSDVPVLPGVPLVVDREGAELLASFHAAKLPSGFI
DRLFAARDVRAEGIRLAVAYGQALIATGEVGGVVIAGGARPGDEAAYAADLATVARELGG
GS
>A0A0C1IKC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leisingera sp. ANG-M7|TrEMBL
MTTPKISFEFFPPQNLEASFRLWDTVQVLSPMGPRFVSVTYGAGGTTRTLTRDAVATLHN
SSGLNVAAHLTCVNASKAETLEIADQFAEAGVTEIVALRGDPPKGEGKFTPHPEGFANSV
ELIEGLKARGNFSIKVGAYPDRHPDAADQAADVEWLKRKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDGTKLTPGILPIENWKGARNFAKRCGTVIPDWVENAFDKALRDGREELLA
TVICTELCSDLLEGGVDKLHFYTLNRPELTRDVCFALGVTPKVSLQNVA
>K0C7L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax dieselolei (strain DSM 16502 / CGMCC 1.3690 / MCCC 1A00001 / B-5)|TrEMBL
MKRISFEFFPPKTDEGRTKLLTTQQKLLAKTPAFFSCTFGAGGSTRDNTREMVDKLREQH
ADTAPHLSCIGQSREEILELVRGYRDSGVRRIVALRGDLPSGMGYAQSEVKYADDLVRLI
REETGDHFTLEVAAYPEMHPQARSFEDDIAHFKRKIDAGANSGLTQYFYNADAYGYYMDA
LRRTGCDAPVYPGIMPILNVANLIRFSGVCGADIPRWLRSKLDDIKDDDQAVKAFGEEVV
TRLCERLLAMGAPGLHFYTMNQAQASLRILDNLGL
>A0A4Z0WFD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronospirillum operosum|TrEMBL
MKFDDEPIPGYSLPILPGHYSPGRLERVLRAGCFAVTTEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYATILQISCRDRNRIAIQGEILGAAAMGAC
NILCLTGDGVQAGDHPGAKPVFDLDSMSLLEIARTMRDESRFQSGRKLDLPPRVFLGAAE
NPFVPPLDFRPHRLAKKVAAGAQFIQTQYCFDIDLLRNFMRKVSDLGLLEGPDRVFILVG
VGPLASARAARWIRANVPGVHIPDAIIERIEGAQNQKAEGVAVCKDLIHQIRQIPGVSGV
HVMAYRQEHTVAEIIEQTGVLAGRVPWYPGRDNPEELNPESPDALQEETL
>A0A3N5K4I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MLNSHPGRDRVLAGMLGKAYLEIIPTGTILERVVHLPQHSYVAITCSPVHGIEPTLALTA
QLRALPEERRLKLIPHIAARMVRDRGHLREILARLDELRVESVFVPGGDAPVPAGVYHSA
LDLLVDMAEIGHTIEDIGVAAHPEGHPHADAAESLRLLRAKQPLATYLVTQMCFDPAALI
AWLRRIREAGVTLPAWIGLPGVADVAKLIALSLRIGVGQSVRVLRKQKGLAGKLISAQPY
QPDDLLQGIHAHLDDPELNIPGFHLFSFNSVEATEGWRQETLCRLETAEGFAHV
>A0A2P6WDC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MDSQLSFSFELFPPRTPEGVTKLPAVIRRLAELHPDYFSITYGAGGSNQEGTYETLMTVI
KQTGVEAVPHLTCVGSTRAHIACLLDRYREAGVKRVVALRGDLPATAMSPSAPGDFHYAN
ELVSFIRETYGNAFKIDVAAYPEMHPQAPSPGVDFENFCRKVEAGADAALTQLFFNADAY
FDFMERCDKAGIKIPVIPGIMPITTFDRTVRFCEGCGADLPRWVRLRLEELQDDKPALLD
FGLGVVTRLCETLLRNGAPGLHFYTINQSEVVQRLWNNLALTTSCEQGH
>K9DDF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium yanoikuyae ATCC 51230|TrEMBL
MTQTDRARNDAEGPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFVSVTY
GAGGSTRERTHNTVARIAKETPLAAAAHLTCVAASKAEIDEVADAYWEAGVRHIVALRGD
PPEAGTAFQPHPDGYKGAAELVEGLRKRHDFEISVAAYPETHPDALSAQSDIDNLKRKID
AGATRAITQFFFEADTFFRFRDTVAAAGIDADVIPGIMPVSNFAAVQRMSAMCNTDVPAW
MGRLFDGLDQHPAARQLVSATLAAELCRNLYMGGVRDFHFYTLNRAELSYAICHLLGLRP
QVAVDA
>G2E444|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiorhodococcus drewsii AZ1|TrEMBL
MSTDTPIYSVELFPPKTPEGMDKLKLEIPKINALGPAYFSVTYGAGGSTRDGTFETVNWL
CSQGIDTAPHLACIGSSRKEVREILTHYREQGIRRLVALRGDMPSGMGAGNSGDFRYANE
LVSFVRAEFGDAFHIEVAAYPEYHPQSGSPSRDLENFKRKVEAGADAAITQYFYNADAYF
SFLESCRRVGIEIPIIPGVMPITNYTQLARFSDACGAEIPRWIRRRLEGYADDVESIRAF
GHEVVANLCRHLIDGGAPGLHFYTMNHSGSVTRLWTDLGLPVARKPG
>A0A0M9YC95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WM6378|TrEMBL
MALGTASTRTDRARTVRDMLATGETTYSFEFYAPKTEKGERNLWNALRRVEAVAPDFVSV
TYGAGGTTRTGTVEATQQITEDTTLTPVAHLTAVGHSVAELRHTVGQYADAGIRNILAVR
GDPKGDPMGEWVKHPQGVTYAAELVALIRESGDFCVGVAAFPEMHPRSVDWDSDIRHFVD
KCRAGADYAITQMFFEPENYSRLRDRVSAAGCETPIIPEVMPVTSVKQLERLPQLSTAAF
PEDLRDRMLAVKDDPAAVRSIGIEFATEFCSRLLADGVPGLHFITLNNSTATLEIYENLG
LHQQA
>A0A3D9C351|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium pennae|TrEMBL
MKITEHIKSANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVDQINNLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A3M1WPE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSLAGILQRKSQRGEKIFSVEISPPMNYPGLVKTSEMVAALKDLDLDSIALTNNTGGSFK
LNPLAVVETVRAVLRSTPIIVHITSRDEGSVRTVYTHVDNMALNGVSDVLVIRGDPSPTN
SRQTDAYKFTTVELVKLMADYSRQQHYALDIFVAGHPEWQSHTLPKHMLYQRQKIEHGAR
GIIANIVTAPENYFRYVDAAQAHEIMVPIVPSVIPLTSVKRCQFLEKRLHIPVPEAVKER
LRTARDKEEARRIGVDISGDIAETLLQRGAPGVNFNVIFPQDVRSVKELLQRVRGYATIW
EKYQIEDPEEIDYFECLREGYF
>A0A0Q8UYX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root79|TrEMBL
MDITTRLRSGQGDVVLFAITPPRRSTPAERLPEIARATIERLQHLDLDGLILYDIDDESS
RNPVERPFPFSPTVDPSDYRAAHLPAWPTPVVVYRAVGKYPREGLQDWIREQDADRTLTV
MVGAASSGTSAPVTLSEAQAMRADLNPDLLLGGVAIPERHSRRDNEHLRLIAKQEAGCRF
FVTQVVYDLNAAKNLVSDYRYACEERGLEPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLRHAKNPLAASLDQAVATAVELVDFCRRLGVPFGVNVESVSIRREEIEASVELASQL
IGHLRADAATP
>A0A532TRU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon Loki_b31|TrEMBL
MEVDVKMTEAKSYSKLGEALAKGDFILTGELEPEKTCDLSHTIEEARQMAPYVVAANVTD
SPLGIVTINSMAATHLIQKATGLECVWQMTVRDVNKLGIAGMIMGAQALGIHNILSLTGD
HTAMGDMPESKPVFDLDSATLIKLVREMVDKGSINGYEIEDPPKLHVGGAANPNSDPMEP
EILKIGRKAEAGCEFIQTQVVYDLDRTIEFLTGIRKYKVPILLGIFPMKSYGIAKGFDTF
VPGVSVPKEILAKWKSVKKEVTDKKQKKELYDQYNYELFKPFIGELRKKGLIDGVHCMAV
HYPRIFPKLMDIIGG
>A0A5I2X3C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Ank|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2N1ZS83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium HGW-Gammaproteobacteria-10|TrEMBL
MQTQQKYPKLFSFEFYPPKTEAGEESLQAVHEKLSRLNPDFFSVTFGAGGSTRDKTFDTV
VKIQERGVAAAPHLSCVASTHENIREILHGYRSNGIKKIVALRGDLPSGMMSAGQFRYAN
ELVDFIRSETGDYFQIHVAAYPETHPQARSAAEDLKNFKRKVDAGANAAITQYFYNAESY
FYFVDACEKMGIDIPIVPGIMPITNYSQLFRFSDMCGADIPRWLRKKLEGFGDDREQIIA
FGCDVVTRLCQQLLDNGAPGLHFYTMNQSAPTLAIWNNLNLSD
>B0UIT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. (strain 4-46)|TrEMBL
MVSTAFRPSRESRRPIRVSFEFFPPKTTEMEETLWSSIERLAPLQPNFVSVTYGAGGSTR
ERTHNTVARLVRETSLKPAAHLTCVAATQEEVDEVVRSYWDAGVRHIVALRGDPAEGVGT
AYRAHPGGYARSCDLVAGIKRIGDFQVSVSAYPERHPEAPSLDADIDALKAKVDNGADRA
ITQFFFDNDLFFRYLDRVQARGIDIPIIPGILPVQNFKQAASFAKRTGASVPEWLAARFE
GLEDDVGTRKLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRALPSAPV
AEKAAA
>A0A2G2F780|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colwellia sp|TrEMBL
MALSLQEKIEDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVVIYDIQDE
SSRTNQARPFPFKQTVDPREYSKLLKDLSRLDVITYKSVAQRGEAEFKEWLDETKNEFDL
KNVVLVGSPSSEGDIKLSLPDAYKTLAEQSDDFFLGGVTIAERHASKRNEHERLIEKTTQ
GCQFFISQAVYNAQATIDLITSYARTCKAQGVTPKRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDSILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKATMELNLAEKQIA
>A0A3E1NQI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deminuibacter soli|TrEMBL
MKVTDHIQQAKDTLISFEVLPPLKGKSISSIYDHLDPLMEFKPSWINVTYHRSETMFKKK
TDGTFEKIDVRKRPGTVGICAAIMNHYQVDAVPHIICGGFTKRDTEDALIDLNFLGIDNV
LVLRGDAAKNEAAFEPEPGGNSYAIDLLKQVSRLNHGLYLDEDIQGGGKTNFCIGVAGYP
EKHFEAPNPEIDMNRLKEKVEAGAEYIMTQMFFDNSKYFAFVDACRKNGINVPIIPGLKP
ITNKKQLSVLPRIFHVDLPTELSNAIMKCKTDAECEQIGTEWLIQQSRELKKQGVPVLHY
YTLGKPKVIHNVVKELV
>A0A4R9K577|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira ognonensis|TrEMBL
MHISEVLNRKKTSISFEFFPPKNEEASEDLFKNIQDLSSLNPAYVSVTYGAGGSTRDLTH
DLVVKLQQKTGLTIVSHLTCVGATKSEIGEILKRYETSGIHNIMALRGDPPKGQKDFVKF
EDGFEYAGELVAYIKQHFPNMGIGVAGFPEGHPATPNRLKEIEYLKWKIDQGADYICTQL
FFDNHDYYDFVERCEIAGIKVPIIAGIMPITSRKSMARMAELSLGSRFPAKLLKSLSRAE
DDLYAENVGIHWATEQVRDLLDHNVAGMHMYTLNKSKATRKIYESLGIRNFDLI
>U7QLK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lyngbya aestuarii BL J|TrEMBL
MNYFRTACSTPGEFIITAEIAPPKGANPTHMIEMANTLKGRVHAVNITDGSRAVLGMSSL
ASAIILKSHGIEPICQMACRDRNRIGLQADLLGADALGIRNVLALTGDPVKVGDHPKAKS
VFDFESVRLLTAIQKLNNGTNWNDKALSDGATDLFAGAAVDPQSPSLSGLKSRFERKLKA
GAQFFQSQLITDFDRLDKFMTEVAAGIDQPILAGIFLLKSAKNARFINKYVPGVKIPEST
IERLEKAPKPLEEGVTIAAEQVKTARQLCRGVHLMAVKREDLISKILDVAGIPPLY
>A0A6A6NK64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hevea brasiliensis|TrEMBL
MKVIDKINAAIGGAGLPEVNANGGGDPNNNRVVFSFEFFPPKTEDGVDNLFERMDRMNMI
CVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQVEGGFACALDL
VKHIRSKYGDYFGITVAGYPEAHPDMIGSDGVATPENYQKDLEYLKRKVDAGADLIITQL
FYDTDIFLKFVNDCRQIGINCPIVPGIMPIYNYKGFLRMTGFCKIKIPAEVTAALEPIKD
NEEAVRAYGIHLGTEMCKKILAYGIKTLHLYTLNMEKSALAILMNLGLIDESKITRSLPW
RRPTNVFRAKEDVRPIFWANRPKSYISRTLGWDQYPHGRWQDSCNPSYGALTDYQFMRAR
ARDKKLHDEWATPLNSIEDILEKFKKHCLGKLKGSPWSELDGLQPETKIINEQLGKINLK
GFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSTDKLQVLVDKCKSFPLVTY
MAVNKGGTLVSNVGPNDVNVVTWGVFPAKQIIQPTVVDPASFNVWKDEAFEIWSRGWASL
YPEDDPSRKLLEEVQSSYFLVSLVDNDYIHGDIFAVFADL
>A0A1G3KRN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium GWB1_27_13|TrEMBL
MLFDYLKNNILITDGGMGTYYYELTGNDNDIIELANLTNPQIIEKIHSDYIKAGAKLVRT
NTFSANTQTLEITKQKLKQIIDSAYSIAKKASQNNAFIAANMGPIPENYNPTEFLDILDE
YYFIIDCFIENGATIFNFETFSDTNHLKEISSYIKQKNPDIFIITSFTFNIDGETRKGIT
IENIFNTICNINTIDVFGLNCGIGPTHLYNILKKLDTSKKIISALPNAGYPEVINERTIY
RHNESYFAEKIIEIRNIGVKIIGGCCGTNPEHIKKITKKLDTEEKKFQTIIKATEEIILK
QETKIVENKFYQKLKLNQFAIAVELDPPTKADFLSIEKGAKQLANNSNVDIVTVADSPSG
RVRLNSMIIASKIKRECGIDTMPHICCRDRNIISLKSDIMAGYLENIRNILAITGDPIPK
EEKNEIKSVFNCNSFTLMSLITELNKNEFINDPVLIGGALSVTFKNPDVVMNRIKKKID
>A0A2T6BC51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmobacter caeni|TrEMBL
MTTPRISFEFFPPQTLDASFKLWETVQMLAPLRPTFASVTYGAGGTTRKLTHEAVTTIGR
NYGLNVAAHLTCVEATKAETLEIAAAYADAGVREIVALRGDAPKGATRFTPHPEGFANSV
ELIEALAATGKFTLRVGAYPEPHPDAADTLADVRWLKRKLDAGATSAITQFFFEAETFLR
FRDLCAKEGITAPIIPGILPIENFAGVKKFASRCGAQVPQWLDDAYATAKRDGREELLSV
ALCTELCDELISEGVEDLHFYTLNRPHLTRDVCHALGISPEVALEKVA
>A0A0K0HG74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella bongori (strain ATCC 43975 / DSM 13772 / NCTC 12419)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3M9MFU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flexivirga caeni|TrEMBL
MWSPRERPDQQNASIPSLLNTGAPTVSFEFMPPRSERAEAVLWNSVRRLEQLRPTFVSVT
YGAGGSTRDRTVRITGRIEQETTLRTVAHLTCVGSSVAQLRSVVGAYAAVGIRNVLALRG
DPPGGPSSPWEAHPEGLDHADRLVALVRSLGDFTVGVAAFPDKHPESASLDDDVDTLIRK
ADAGAAFAITQMVTDVDAYLRLRDRLSRRGCRMPVIPGLLPVTAPGQLQRLTELNGQPLA
ADVMRRIAEAGDDVDAVRREGIAICTEHSERLLREGAPGLHFMTMNKSTATLEVFATLRE
LGLV
>A0A646FSA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIAEFLHQKGDKRGFSFEVLPPLKGNGTAALFRTIDSLKDFDPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHVICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHSNATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMKHLLEKQQLGADYAITQLFYDNEKFYAFVEKARQMGITIPIVPALK
PFAKLSQLTMVPKTFHCDIPEALTQEVLKCKSDEDAKALGIEWTTAQVKDLFDHGYNHIH
FFTVSAVDSVKQIAKILF
>A0A1C0ST70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. LC54|TrEMBL
MTNSSEACTETRIDPSSGGEATISIELAPEQVRSFAPQADTLPLGSRVFLTHLAGKPEAL
QVEAAARITEMGYVAVPHLAARNFKTERDFVALVHAHSRNGIDEVLFLGGNPALFPGPLG
ESAELLAHPVLADSAIRTAFVAGYPEGHPNIPADRLKDALKRKLEICARRSLEPRIVSQF
AFDGGMIGAWAKQLHRDYPEVPVHVGLAGVTSLTKLIRFAAMCGVGPSLATLRRSASGLL
NIIADRNPGDVLDAIASAYPIPPTPLHLHFFPFGGWEKTLTWLDDYREARQMGAGAR
>A0A542EG85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yimella lutea|TrEMBL
MPDASARPHPSIPDLLHAPDTAFSFEFFPPKDDASEAILWDSIRRVERIRPSFVSVTYGA
GGSTRDRTVRVTSRIEHETTLTTMAHLTCVGSSTTELRQIVGQYAGAGIRNILALRGDPA
GGLGTPWTPHPGGLDHADQLVGLIRELGEFTVGVAAFPDKHPESGSLEEDAQVLIRKAQA
GASFAITQMVTDVDAYLRLRDLVAASGRSIPIVPGLMPVTAYGQLQRMTELNGQPLAAEV
VERIEAVKDDRSAVREVGIQICTEHAQRMLAEGAPGLHFITMNRSTATLEVHRNLVG
>A0A0M3G6D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus haemolyticus|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWDSGIRRIVALRGDEP
KGYAKKSFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIESYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPE
>C0QKS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforapulum autotrophicum (strain ATCC 43914 / DSM 3382 / VKM B-1955 / HRM2)|TrEMBL
MKPLTPSRLEKILKLGHVAVTSECGPPRGSDPMAVISKGELIRNHVDAVNITDNQTSMTR
MCSLAACIHLKKLGIEPVLQMVTRDRNRIAIQSDILGAASFDINNILCLTGDHQSFGDSA
QGQNVHDLDSMQLIQTVRMMRDRGRFLGGDEIKRPPAMFVGAAANPFADPFEIRVPRLAK
KVACGVEFIQTQCIYNLEKFELWMEGVRERGLDERVFIMAGMTPMKSVGMAKFMKNRVPG
MDVPDEIIKRLAGVPKEHQAQEGLDICIEAIQRLKACKGVSGFHIMAIEWEEKVPEIVER
SGLYPRPEV
>X6IIJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L2C054A000|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTIKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A3R6FZJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHTHATDLLKQVNLFNEGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDDDAKQLGIEWTTAQVQDLFEHGYNNVH
FFTVSAVDSVKQIAKILF
>A0A2N5DQX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter zeae|TrEMBL
MTLPPTRRVIGPVARAGERPVGAARPRVSFEFFPPKTEKMEASLWEAITRLAPLDPAFVS
VTYGAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRAEVDEVIHDYWNIGVRHIVSL
RGDPPPGEGGIGGVYVPREDGYKNATELTAALRGIAPFEVLVGVYPERHPESPSLDHDID
VLKAKVDAGATLGISQFFFDIDAFLRFVDKARAAGITIPIVPGVMPVTNFKGLKTMSAAC
QTSVPSWLANLFEGLDEDPETRRLIACSVAAEMCAKLQEQGFNDFHFYTLNRADLVYAIC
RVLGVRETAPAHEAAA
>R6ZYM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:875|TrEMBL
MKVIDLIKNSKEPIFSFEILPPLKGNSIQKVYHVIDKLREFDPKYINITAHHSEIVYLPQ
PDGNLKKTTVRKRPGTVAIAAAIQNKYGIQAVPHIICKGFTKEETEYALLDLNFLGITNL
LLLRGDSKPLDIAAKDLYLYNEHATDLQEQVNRFNQGISLDGSKIEGIETPFSYGMACYP
EKHEEAPNMESDLFYLKEKVRNGADYVVTQMFFDNEKYYAFVDRCRQEGIEVPIIPGIKP
VVFKNQLNVLPKVFRTDIPEAFASELRKCENDEEVKAVGVEWCKAQCKDLLAHGVPGLHF
YTFMASDSVYKVAKEIY
>A0A5N7XEP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A1C0SQ73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. LC54|TrEMBL
MTAQTLYPAERGNLRLSFEYFPPKTDEMEAQLFQTAEDLSVFSPAFVTVTYGAGGSTKAR
SLTTVKRMIEEKGFANTAAHLTCVGAPTAEVDTVIDEFLAFGVRHFVALRGDPQGGIGST
YQPFPGGYESSSDLVRALRDRGDVEISVSSYPEKHPESPDVAADIDMLKRKVDAGATRAL
TQFFFDNDDFERYLERVRRAGIEIPIVPGILPINNLSQVQKFAGLCGASVPEVIVTRLSH
LEGQPAERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFERADEMSRA
EEISLKAVAGAAA
>N9L107|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii NIPH 80|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEHFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQVGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEITRFSCQPTSKQLIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILREKLIPTVPLETRGTSSWKNWYLATEA
>A0A6G6Y2A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingosinithalassobacter tenebrarum|TrEMBL
MNDQRNQREEERRAHDAPLFADMAGDLDVSFEFFPPKNEKMEATLWDSIQTLAPLGPRFV
SVTYGAGGSTRERTHATVARIARETDLAAAAHLTCVEATKEEIDAVAEEYWAAGIRHIVA
LRGDPPEKGAKYQTHPGGYENAAALVEGLRKLHPFEISVAAYPECHPDSPDDRADLDNLK
RKLDAGATRAITQFFFDADHFFRFRDKVAAAGIDAEIVPGIMPVMNYGAVERMSKMCGTE
VPSWMGRLFEGLDDHPEARQLVSATIAAELCRKLYAGGERSFHFYTLNRAELSYAICHLL
GMRAKPSAEAAAA
>A0A0U1QQS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporolactobacillus inulinus CASD|TrEMBL
MGQSILDVLKERILIGDGAMGTLLYSYGIDRCFEELNVSQSEAVRHVHQAYINAGADVIQ
TNSYGANRIKLARYGLEHEVARFNRASVQLAKQAAKPETFVLGTIGGIRGFQKQSVELDT
IRASFREQADALLSEGIDALLLETYYDFDELRDVLQIARTMTDLPIITHVSMQEPGVLQN
GMPVAEALEGLEAQGADVVGTNCRLGPFHMIEALRGIPLPKKAFLSAYPNSSLPDYRDGK
LHYENEPEYFKKYAVEFRNEGVRLLGGCCGTTPVQIKAFKEGISALEPLETKVVTVHPEV
VHVSEAAEPPESALYQKSVNGRSVFVEFDTPRHLNTDHFFRGVQALEAAGADAITMADNS
LASPRISNAAIGKLIKDRYHMPPLVHLTCRDRNLIGLQSHLLGLDVLGLHDLLVITGDPT
KIGDFPGATSVYDVSSMELIKLIKQFNRGISYSGKSLKKPTHFRVAAAFNPNVRNLDRAV
QRLKRKIECGADYFISQPVFDKERIIAISEATRGVSAPIYIGIMPLTSARNAEFLHNEVP
GIRLPDDVRAKMAATSGKEEARQMSFAICRELIDTAMAHFRGIYLITPMGHYSMSVDLVK
YIKKKEREYAALENSENILL
>Q8KCP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)|TrEMBL
MLVKEIFDARTEPVFSLEFFPPKKQDDWDKLFETISNLFPLDPSYVSVTYGAGGSTRERT
HNLVTRIQQETGLTVVSHLTCIGAEKSEIESVLQNYREHGITNVLALRGDKPADITTLEE
ATKDFPHAIDLVKFIKENFPEMGIGVAGFPEGHPETPNRMKELEFLKEKVDAGADYIVTQ
LFFDNHDYFDYVERCELAGITVPIIPGIMPIMSKKGMIRMCELALGSRIPSKLLRKVLEA
ADDKEVAEIGVEWATNQVQELLDHKVKGVHFYTLNLSEATLKIFRNLKRG
>A0A6A5Y7D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aaosphaeria arxii CBS 175.79|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTSMGFANLSSRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRSLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDDAQLPEEDSNRDFTWAIDLVKYIRAKYGDYFCIGVAAYPEGHSDESYPEHQDPARDL
PYLVEKVQAGADFVMTQLFFEVKAYDKFEKSLRTHESGAFKTIPIIPGLMPIQSYSILRR
TTKLSHAKLPGKMLERLDAVQTDDELVKKVGVDILSEMVDHIKKQTSASRRGFHFYTLNL
EKAVSHVLENCHLIPPTLQEEDEEAVVDITGPGIFVQPPEGAQNSQRRRVSSVNSSPHNR
IIVSRPSKSSNPSYEAWDDEAGIPKGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVAKDDISTLFRKHIQGEIDALPWSEQGLAP
ETSTISKELLSLNAKGWWTVASQPAVNGVKSTDPVYGWGPKNGFVFQKPFVEFFIPASDW
KKLQPRLDAHEQVTYFAGNAKGDFEASSDDGVNPVTWGTFAGKEIVTPTIIEEVSFKSWI
EEAYSIWKEWQRVYPPRSASSKFLGECWEDCWLVNVIWGDYVQGHGLWDFLKAEL
>Q1IL23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Koribacter versatilis (strain Ellin345)|TrEMBL
MGKSFLERLGDGPILCDGAMGTLLYSKGIFINRCYDELNLSQPELIGGIHADYVANGAEI
LETNTFGANSFRLARHGCQEKLADINRAGVELVRKAIKNNQVYAAGAVGPLGIRIEPLGK
TSRDEARDAFRDQIRVLVDSGVDLLILETFGYLGELHQAILAARDVDPKIPVVAQVTIDE
DGNCLDGSSPEHYGARLTEWGADVIGCNCSVGPVAMLDALERLRAATPKPLSAQPNAGIP
RSVEGRNIYLCSPEYMASYARKFVGVGVTLVGGCCGTTPDHIRSMKSALRVGEARTTSFK
VKTEVEEHAVEPTPLGQRSRVGARIASGEFLTLVEIVPPKGVNAEKEVEGARYLMSVGVD
AINIPDSPRASARMSNQALCLLTQQQVGIETVLHYTCRDRNVLGIQSDLLGASAIGIRNL
ICITGDPPKMGNYPDATAVFDVDAIGLVNIVSNLNRGLDIGGNTIGTATQFTIAVGANPG
AANLDEEIRRFEYKVEAGAEYAVTQPVFDLALLEEFLKRIEHCRVPVVAGIWPLSSARNA
EFMRDELNISIPDAIYNRMARTTNADAARAEGVAVAREMLQAVRPMVQGTQLSAPFGRYS
AAADVLEVLGSSDSACA
>A0A6H2KV07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sanguinis|TrEMBL
MSVRRTVPAVSFEFFPPKTLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVT
ALATHYGLNVAAHLTCVEATRAETMQIVDDYAAAGVREIVALRGDAPQGAAAWTPHPEGF
ASSVELIEAISARGGFTIRCGAYPEPHPDSPDSAADVAFLKRKVDAGATSAITQFFFDPD
TFFRFRDACAAAGIAAPVIPGILPIQSWAGAKRFAARCGTSVPAWAEDAFARAGKPGEAA
LARDIAVELCTRLIEGGVDRLHFYTLNRPELTAEVCAALGIEATEAAA
>A0A1V4WCS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdus sp. PtaB.Bin006|TrEMBL
MLKNRFREILEKREQFVYTVELVPGRGSKGKTHDDVLDLANKASQGGLIHAMSITDNPGG
HPALTPGVLGVEIARMGIDPIVHFTCKDKNRNEIESILYGLDRIGIRNLLAMTGDFPLYG
FEGKTKPVFDLDSVQLLHLITKMNEGLQIDARAPGGGRILPPTRMFKGCAVSPFKQLESE
TLAQYFKLWKKVQAGADFVITQVGFDARKFDELLRYMRHLDIKVPVLGNVYILNFPVARV
MNRNAVPGCVVTDQLFRICEEESKAPDKGKTARLIRAAKLIAVLRGIGYNGVHIGGPNLK
YEDIEWVIGKSIELSGIWPSLVSEFDYPQPGGFYLYEKDNNTGLNADNLTGRKSSPGKST
GYALMRFFHHLVFAADAPFYKPVCSFFKKVNGTRLEGVLTELEYWIKFVSSGCRRCGDCA
LADIAFLCPQSQCPKFLLNGQCGGSSEGWCEVFPGKRRCIFVRAYDRLKAFGEEGSLRGT
YIRPRHWELDQTSSWANYFLGRDHNVEKCNGKPQGRP
>A0A0R2Z5P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas synxantha|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKIPAAPHLSCVGDSKDDLRGLLTHYQQAGIQRIVALRGDLPSGMGMASGELRYANEL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A142HFI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp. PAMC 26554|TrEMBL
MKVTDHLARAAGKTLFSFEVLPPRKGENIHSLFANIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRKRPGTVGICAAIKNRFDVDTVPHLICGGFAKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFQPHPDGHTYACDLIGQIDSLNHGRYHDHDEQYQPAGAEPVLCTDF
CIGTAGYPEKHFEAPNNGSDIRFLKDKIDRGADYIVTQMFFDNEEFFKFEKRCREAGITV
PIIPGLKPLTTKAQLTALPRAFFLSIPEALAEAIHQAPDNAAAREVGIEWCLHQSRELQA
HGVPCLHYYSMGKAEAIRRVAAELF
>A0A317WK34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus sclerotioniger CBS 115572|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDGQDPERDLPYL
VEKTQAGADFIMTQLTYDMDAYTRFESMLRNHESGAFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPHILSKLDEVKHDDDAVKRIGVDIISDLVYGIRDLGCTGPRGFHFYTLNLEKT
VSFILERCELIPPYSEIDDSDALVDGGNLSAMDSSSYVAPNGAQIRNLASRRSSVSSIPH
NRVIVDKVLISEASSKGSVTHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVPAPIARQIWGYPVSREDISTLFRRHVSGELYMVPWS
EGGAEENSNGLNAETAVIQTELLTLIDKKGWWTLASQPAINGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPDKDYQTVLKPLFQKHGHEKLAWFATNVKGDFESSLPGPNPDDPDPIDIN
PANVNAVTWGVFRGKEIVSPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLNQTK
NDVWLVCVVGQEFGAGTEAGSEEEEDEKKWMWRELANSQ
>F0B927|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas vesicatoria ATCC 35937|TrEMBL
MAQPLIDPETSSLASALTADYSLEISANDIAGLAAAAPGMLRGSTIAIPYLPNQDDDARL
EAARRVRALGFQPMPHLSARRIGSRDALHTFVRRAVDEAGVARCLVIAGDPPVPAGPFPD
SLSLIETGVFERSGIQTIAVAGHPEGHPSMHATDQWDVLDRKCRSIAGRGMAPLIVTQFA
FDADIVLAWLQALRAHGIQHPVRMGVPGPAGVAVLARYAARCGVGACTAMLSKYGISLGK
LFGTTGPERFVDRLATGLTEAHGAVSLHFYPFGGVAQTVAWVERYRSRIARPGLD
>A0A1T4XPK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paucidesulfovibrio gracilis DSM 16080|TrEMBL
MQERIPDLIRPGTPFVSFEFFPPRDEEARQRMLRVGEELKVLHPLFVSVTCGAGGGGGRG
TLQAANMLHTALGYRVMPHLTCCGLEPKGVDDALAQFQANGINNVLALRGDGTDGNGPDG
DAPLQHASDLVEHIRKSYPDIALGVAAYPEPHPQSPSVQADIDMLRFKLDAGSDFGVTQL
FFDNRRYFDMVERLADQGCHKPVIPGIMPLRTMASARRILSLCGAAIPGNLYAALEKAHA
QGGDDAVREVGTAHAVQQVQGLLNGGAPGIHLYPLNQSSQCLDVAQQAGLLG
>A0A285VSK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ornithinimicrobium cerasi|TrEMBL
MTGPQTRISVELVPRSAESLAAEVGDIASRLPWVSTINVPDLLKFELRSWDACGLLRALP
ARPDGRAYPAIPHVRAADVDPDAPLPMAEAIVEHGVEEVLVVSGDDADYFTHHTYPVDAV
DVIRRFRAELPHVKVYAGLDPYRNGIAAEMRYLERKLSAGAAGVFTQPFFDTSYLRAWSA
LLPEDLEVWWGATTVTTPASVGYWRRRNMVAFPRDFELTLQWQRDLARRVIDVAQEQGQH
VYLMPVRTSVLDYLDGVL
>A0A4D6XTW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MRFSKNKYHKDIIDQKLNNLNKKIKCSFEFFPPKNIDLEEKLFSSVIKLNELKPFFFSVT
YGANSGEREKTYKIVKKIHEKTGVITAPHLTCVDSSPIELEKIAKFYWKNGIRSIFALRG
DSNNTDHSHRMYAYDLVMLLKKIANFDISVAAYPEVHPESPNAQLDILNLKKKIDAGANR
AITQFFFNTESYLRFRDNCIKNNINVEIVPGILPIYNFEQLKRFAKMTNVKIPSWMFEIF
DKLTDDVMSQKIIGASIIIDIIKSLSEEGVKNFHFYTLNQSDIVYSICRLFGF
>A0A5B0VWP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium tropici|TrEMBL
MSHIDENPLGVHLPLDPLPGHYSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLTEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDAVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRSDALVAERLHQISEGREENQQAMAEIAA
HHTPPQTH
>A0A0L8N195|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces virginiae|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSVAELRNVIGQFADAGIRNMLVVRG
DPPGDPMGEWVAHPEGVHYAADLVRLVKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CHAGADYAITQMFFDPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSNAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A0P1IP15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shimia thalassica|TrEMBL
MIGTKNMTAPAISYEFFPPQNLEASFRLWDTVQTLAPMDPRFVSVTYGAGGTTRDLTRDA
VATLHKSSGLNVAAHLTCVDATKAETLAIAEEFARVGVNEIVALRGDPPKGSDGFVPHPD
GFANSVELIEALADTGKFTIRVGAYPDKHPEASNAQADIDWLKRKIDAGASEAITQFFFE
PETFLRFRDACAAAGIDAPIIPGILPIENWKGARNFAKRCGTDIPRWLDDAFSKAERDGR
TDLLATALCTELCSDLMDEGVDALHFYTLNRPELTRDVCFALGITPNVALENVA
>A0A1J5KMH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteriovorax sp. MedPE-SWde|TrEMBL
MKVIEHIDKSSNPLFSFEIVPPPRGRTIEAVIEVVNTLQPYNPSWVDVTAHPAGAYYNEK
NDGSIERKIYKKRPGTIGICGVIQNRFRIDTVTHLLTQGFTKEETEDALIELNYLGIHNV
LALRGDGLNYNKQYDKVKHRNHYAIDLVDQINDVKKGIYLDEINQSIPMDFCVGVAGYPE
KHFEAPNLKLDIQRLKNKVDAGSDYIVTQMFFDNQKYFDFVKSCREADITCPIVPGIKVI
KNLKQFRSVPSHFYVDFPDEFVEEAHENPDHVEEIGVRWAIKQGEELLNANVPSLHFYVM
NDAKSVSQVVKKLF
>N9KVZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii NIPH 80|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A3B8S088|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrionales bacterium|TrEMBL
MTGTNQHPVSFEFFPPKTEVGMNKLQETRRVLGQLNPEYFSVTYGAGGSTRDNTKKVVLE
GIEAGFNTAPHLSFGGDEKEAILNLLKEYQANDVSRIVALRGDLPSGFGAGSRLVHANEL
VSFIREHTGDHFHLAVAAYPEIHPEADSYDSDIHFLKQKFDAGANSAITQYFFNPDAYAF
FIERCQKAGIDQPIYPGIMPITNFDNLKRFSQSCGAEIPRWLTYRVESLKDSPEDQKAFC
TEFMTTLCEKLLSYGAPGLHFYTMNQIEPTQSICHNLNIK
>A0A3D1MH49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp|TrEMBL
MIAANAQGTGFPVSFEFFPPKTPEGADKLRAARQQLYALRPDFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPEADLNAYIAKVQAGADSAITQYFYNSD
AYFRFVEDTQRLGANVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A1V5MJT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division TA06 bacterium ADurb.Bin417|TrEMBL
MTFKEKLKTDRFLATVEYGPEKGIATEPFLQMAREIGGRVDGINVTDLQSAVMRLGSLAL
CIKLKEAGQEPILQMTCRDRNRLALQSDLLSAAAFGIENVLLLTGDHPVLGDDPAAKPVF
DLDSIQLLETARRLESGLDSAGNKLNEPFPRFCLGAVVNPGAEPLELQLIKLEKKVAAGA
EFIQTQAVYEVERFEKFMKEAGRFGIPVMAGIVLLKSAGMAKYMNENVAGVHVPDTFIKR
MADAPKEKRSAESIAIAAELIGAMRGLCRGVHIMPIGWERHLPRVLDTAGL
>A0A1J5N0J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio hydrargyri|TrEMBL
MRVCDLIDGKSPFVSLEFFPPKEREAWPAFFEVVDKLKVLDPLFASVTYGAGGGTQDNTL
EIATRMKRDHGLEPITHLTSVGASAEKLDGFLESLVKAGIDNVLALRGDPPRGVENFDFS
SQDFRHASELIEYICSRYPDLCVGGAAYPEPHCESPSIKSDLDMVHLKVRKGAKFLVTQM
FFDNRMYFDYVERLKLMGANVPVIPGVMPLLSLKSAKFILSLCGAAIPGKFLSALEKAHE
EGGDDAVYALGIDYATKQAQELIDGGAPGVHLYTLNRAEAVLEIGKNLNI
>A0A319DUC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus ellipticus CBS 707.79|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNREFTFAVDLVRYIKEQYGDYFCIGVAAYPEGHPADNAQDRQDPERDLPYL
VEKTQAGADFIMTQLTYDLEAYTKFETRLRNHESGAFKTIPILPGLMPIHSYKILTRVTK
LSHVQVPPQILAKLEEVKYDDDAVKHIGVDIISNIVHGIRDLPGSKLRGFHFYTLNLEKT
VSFILERCELIPPYSEYDNDEALADGGNLSALDSSSYLAPNGTQIRNLTSRRSSVSSIPH
NRVIVDKIQASEGSSNHSVTHEALALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVPPSGARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEENSSGLNAETAVIRSELLTLIDKKGWWTLASQPAINGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPTKDFQSVLKPLFQKHGHEKLAWFATNSKGDFESSLPGPNTDDADPIDIN
PANVNAVTWGVFRGKEIVSPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDQTK
NDVWLVCVVGQEFGAGTEVGSQEEEDEVKWMWRELANSQ
>A0A413VII8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides nordii|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLCRDIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNKLRRRPGTVAVAAAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYYHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDSDIYWLKKKVEAGAEYAVTQLFYDNQKYFDFVEKARQEGINIPIIPGIKP
FKKASQLSMIPKTFKVDLPDDLVKEALKCKNEAEVQQVGVEWCVKQCRELMAHGVSSIHF
YSIGAVDSIKEVAKEIY
>A0A1Y2MWI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces platensis|TrEMBL
MRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALRGDPPGDPMGEWVRHP
DGVGYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVTKCRAGADFAITQMFF
YPEDYFRLRDRVTAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQQS
>A0A0J6FRZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. NCPPB 1128|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
RFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRADLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQANDALSDLRHFKAKVDAGADAAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAEAIRDFGADVV
ATLCQRLIDGGAPGLHFYTLNLAKPTTSVLARLRGAIDAG
>A0A021WX92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp. DD12|TrEMBL
MNKATARPARKDIRLSFEFFPPKSAEAEGQLWETAAALSAYDPGFMSVTYGAGGSTKAPT
LATVRQLLAMGLPAASHLTCVGATKEEVHAVVAEFQAVGVKHFVALRGDPPGGVGTAYQP
YPGGYANAAELTAGLRGLADFEISVSAYPEKHPQSPDVAADIDMLKRKVDAGATRALTQF
FFENDDFERYLERVRKAGISIPVVPGILPVHNLSQVQKFAGLCGASVPDWLADRLAPVDD
RPQERAAVAIDLAARQVEDLIARGIGEFHFYTMNRATLVSAVCDRAGFARSERQPAGAAA
>V8BY22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ruminococcus] lactaris CC59_002D|TrEMBL
MKIIDRLNEDRINISFEVFPPKTDAGFANVQRATDEIAKLDPSYISVTYGAGGGTSKNTA
KIASHIKDDLHVLSLAHLTCASSTKEEVREVIRNLKELGIENILALRGDIPEGMKFPDGD
RFHYAYELVEEIRKQGDFCIGAACYPEGHVENEHKEDDIRFLKQKVDCGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLALLDRFGSSPE
AMMQAGIAYATDQIIDLLANGVKNIHIYSMNKPEVATKIMSNISEIIKC
>A0A7G2MJD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricimonas sp|TrEMBL
MKVIDILNKSDKAVFSFELVPPLKGGDINKIYEAIEPLIALAPPFINITFHRDEVVYREY
PDGTIKKVTVTKRPGSVALAAAIMRRYNVDMVPHIVCGGATRHKIENELIDLNFLDIENV
MALRGDPIPGERFFTPEEDGHQYSCELVEQITRMNHGQYLDDTLTEAVPTNFCIGVAGYP
EKHYEAPNQACDIENLKKKVDAGANYIVTQMFFDNSKFFQFVDKCRAQGINVPIVPGLKP
ISTFKHLEMLPRTFSIDIPHELVKEIRSCKNNKEINQVGIEWCVAQSKELIAYGVPAVHY
YTMGKSENIQEIVKQVF
>A0A6B1DSZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineaceae bacterium SB0662_bin_9|TrEMBL
MVPFLEALQAGPLLADGGMGTLLLAHGARVDQNLEELCLTEPDRVRELQLAYARAGADIL
LTHTFGAQSLRLAEHGLDSQVVAINRAAARIARDVRESSGRDIFIAGDIGPLGRALAPRG
PISTEQARTAFREQAAALLEGGVDLFCVETMTDVAELRQAVLAIRELSDLPVLASLTFSA
DGETLFGLDAAAAAEMLTDLPIDVLGANCAVGPTALLDVLATLRAARPGIWLSAIPNAGL
PTRVDGRFQYEAGPEYFAAMVPEFLARGARIVGGCCGTTPAHIRAMRQALDSIESDHEGD
SVHLETEPSVEWGVRVSETGGPHASDPVSASGLLAKMRAGEFVVSVEVDPPRGLNPERQL
AGARLAKERGADAINVADSPMARVRMGALALSTLIENRVGIETILHFTTRDRSLMGLQAD
LLGAHALGLRNILALTGDPPSLGESQNSSPVYDTDSVGLVQILQQFNRGQDLQGKEMGQH
SSFAIAVACDPTRPDLELETERLTRKLQHGADFIMTQPIYDPMVWIRFADLYASRYGPIP
APVLIGILPLQSFRHASFLHHEVPGITLTPTALNSMKEAGKQGRQAGVAMAQDLLLDLID
APHVQGVYLMPSFGRYETACRVLDVLDRTPVREVA
>A0A8J7UW90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronogracilivirgula saccharolytica|TrEMBL
MKVIEHYEKAKDPLISFEIIPPKRGGSVTKVFETLDGVMKYHPPFIDVTSHAAEAYYEEL
KDGSVKRHIRRKRPGTIGLCAAIKHRYNVDPVPHLICKGFTKEETEDALIELNYLGIENV
LAIRGDDQGYQKPVQKSRGINEYAVDLVQQIKRMNSGVYLEDLMDAESTDFCIGVGGYPE
KHIQAPNMEYDIARLKEKVEAGADYIVTQMFFDNTAYFRFVEMCRDAGITVPIVPGLKVL
TTPRHLQSLPQFFHLSIPAPLTREVSENPDRARDIGVEWAVKQCRELLDYGVPGLHFYVM
GNPKPATRVIDQLDIVPVSAVSSKK
>A0A5B0T5Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter portucalensis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A4V2TS80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neorhizobium sp. JUb45|TrEMBL
MQTKAPEQKSGKNFRLSFEFFPPKSADMETQLWESVADLTDWNPEFVSVTYGAGGSTKAP
TMTAIQRLLAETPLAAASHLTCVDAAREETLGVIEELRAAGVRHIVALRGDPSAGIGTAY
QPHPDGYANAAELVAALKDVGGFEISVSAYPEKHPESLDTNADIEMLKRKADNGADRALT
QFFFDNDVFERYMDKVRAAGITLPVVPGIMPIQNLTMLKRFAGRCGSTVPEFLDQRFAGT
EDDAVARAEVAADVAAEQIEDLIRRGLGEFHIYTMNRSALTNAVLERLGRQRVPVKAGAA
A
>A0A849UKI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp|TrEMBL
MSTSTLSFEFFPPKTTDGIEKLRENREKLAKFNPEFFSVTFGAGGSTRDRTMDTVLEIQH
EGYQAAPHISCVSSSKEEIRELLQLYQTQGIKRLVALRGDVPSGEVSAGDFRYAVELVDF
IRAETGDHFHIEVAAYPEFHPEARTPAADLLNLKRKVDAGADSAITQYFYNADAYFRFID
QCAATGINIPIVPGIMPIYNITQLARFSSVCGAEIPRWLKMRLEEYGDDIESLRAFGVDV
VSELCETLQTWGVPSLHFYTLNRSTIISKIIENIGE
>F0J205|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiphilium multivorum (strain DSM 11245 / JCM 8867 / NBRC 100883 / AIU 301)|TrEMBL
MSHTPPRAVLERWLSGPRVDPLPTPALRAPAPAISFEFFPPKTETLEAQLWACIRRLEPL
APRFVSITYGAGGSTQERTHATVTRLVRETTLVPAAHLTCVGASRGEVDDVARRYWDAGV
RHIVALRGDPPGGTAYAPHPEGYAYAADLVAGLRRVADFEISVAAYPETHTQAPSPQADL
DNLKRKLDAGATRAISQVFFETGHFLDFLDRALAAGITAPIIPGIMPVSNFGQAKRISEM
AGTHVPAWMGEMFDGLDDDAETRKMVAASIAAEQVRTLQANGIDEFHFYTLNRADLTYAI
ARILGVKPAR
>A0A0S8DG79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira bacterium SG8_35_1|TrEMBL
MSLKSALESGKFTVTAEVGPPKGTDIAKILHEAEALKGKVDALNVTDNQSAVMRISSMSF
CKLLLDMGQEPILQMTCRDRNRIGLQSDLLGASILGIRNVLCMTGDHPNAGDHKEAKPVY
DIESVQLLNIVRALNSGKDMMGNEMKGGTDYYQGAVVTPEAVPIEPQLMKFEKKVNAGAQ
FFQTQAIYDIEKFKGFMEFAGKFPVKILAGLVLLKSAGMANFMNKFVPGITVPQELIDEL
KEAGKEKALDAGIDIMARHIKQLKDEKICDGVHIMAIGAEDKVPLIMERAGLL
>A0A2H0YZ68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium CG08_land_8_20_14_0_20_37_9|TrEMBL
KKEFVKLVELVSPKGVSPSREVDKARKLYHAGIDAINIPDGPRASARMSALALAAIIQKE
VGIETVLHIACRDRNVIGMQSDLLGAWALGLRNILAITGDPPKLGNYPDATAVFDVDAIG
LTNIINRLNHGLDIASNPIGDPTGFCVGVGVNPGAINLDEELKRLEWKIEAGAEFMITQP
VFDIKLLEHFMKRIEKIKLPLICGIWPLVSFRNAEFMNNEVPGASVPQKILQRMKKMTTK
EEGFNEGVKIARETFDQVKTFADGVQISAPLGRIEAIFDMIE
>A0A0Q8MU95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Root708|TrEMBL
MALNSDARRKIGISFEFFPPKSEEMEGQLWNTVSELQDWNPDFVSVTYGAGGTTKAPTLA
TVSRFLADTPLATASHLTCVGATKEETHGVIETFRKAGVKHFVALRGDAPGGVGAPYQPH
PGGYANAAALVAGLRELGDFEISVSAYPEKHPESRDIAADIDMLKQKADNGADRALTQFF
FDNDSFERYLEKVRAAGINIPVVPGIMPILNLTQLKRFAGACGTSIPAFLDERFAGYDDK
PEERAKVAAEVAAEQIEDLARRGLAEFHLYTMNRAPLVSAVMTNLGFKRDGVKNTGAAA
>A0A6C2D2T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zoogloea oleivorans|TrEMBL
MSNKTPFSIEFFPPQTSEGVEKLRATRAKLAELKPEFFSVTFGAGGSTQARTFETVFEIQ
REGHQAAPHLSCIGSTREHVREILARYKTEGIRRIVALRGDLPSGVGDPGELRYANELVE
FIRAETGDHFHIEVAAYPEYHPQAKSPKDDLLAFKRKVDAGANSAITQYFYNLDAYLHFR
DECAALGVNVPIVPGIMPIVSFSKLARFSDACGAEIPRWMRRKFEAFGDDSDSIKAFGLD
VVSELCAKLIAAGAPGLHFYSMNQAAPTIALCERLGLGR
>A0A5S9IPF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Uabimicrobium amorphum|TrEMBL
MKITDHIKNAKNLPLFSFELLPPVKGDGIGSIFKLIDELMPFNPAFIDVTYHRQDYTYVE
SSDGKIEKRPYRKRPGTVGISAAVINRYGVDVVPHMVCGGFSKQVTEDALIDLHFLGIHN
ILALQGDKLSHDKQFIAEKDGHQYASDLLGQINDMNNEKYIDPDLVVKDATNFCVGVAGY
PEKHYQAANMETDMFYLKKKIDMGAEFVITQMFFDNQKYFSFVDKCREMGINVPIIPGLK
PITSRRQLQILPSTFFIDIPVELTQKIEEARTGKEVRDAGREWCTKQCQELIEYGVPSLH
FYTMGKINPVKQIAADIFS
>A0A8J3DNU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limoniibacter endophyticus|TrEMBL
MSAYRLSRSPELGKKISISFEFFPPKTDEMAERLWETVKRLEPIAPKFVSVTYGAGGSTR
ERTSRTIERMLSESALSPAAHLTCVDATKEEVDHVIEDFAQMGVKRFVALRGDPTAGVGT
AYQPHPGGYSNGAELCGALKRIGNFDVSVSAYPEKHPESPDFATDIDMLKRKVDSGADRA
ITQFFFDNDLYERYVERVRKAGIYIPIVPGILPIHNFKQVAGFAGRCGASIPTWLAERFS
GLENEPQTHQLVAAAIAAEQVLDLVERGIDDFHFYTMNRADLPFAIAHMIGVRPKVAEAA
A
>A0A1N6FZJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum sp. ES.010|TrEMBL
MEAAPVSQPTDALLQRLFEAGGAVPLSFELFPPRTEERRRALHETVDRLAPVADDGFSVT
MGAGGTTRTGTHDTAVEVAQRSGRAVTAHVTALGLTEAQVLDAAEGLWAAGIARILALRG
DRPRTTAGPMPPGFAHAAELVAALAARHPFEIAVAAYPEKHPEAGTMSEDIDHLKEKLDA
GARRAYCQFVLDPAAYGRFLDTCARHGIDAPIIPGLMPLEGWTRLRGFARANAARVPDWL
DRLFAQGEETPELMPYLAAAATAEQARRLIAYGAPALHVYCMNRWPLPLALARLLGHR
>A0A1F9V078|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_64_13|TrEMBL
MKITEILKKKKPVFSCEFFPPKTEEGMDQLFGTIAEFRALGPAFVSVTYGAGGGTRDKTI
GIASRVKKEMGLETMAHLTCVGHSRAEIRSILDRLRSEGVENLIALRGDPPKGESSFVPH
PDGFRYAGELVEFARTGYDFCVAVAGYPEGHVEAPDRETDWKRLDGKIAQGGEVVITQLF
FDNAEFFAFDRRMKAKGAEVPILPGIMPITNFSQIEKFAKMCGAKIPAEVARALEPVKED
LEAVQDYGVRYAVRQCEELIRKGVSGVHFYTLNKTRSTRAIVLELKKKGLLA
>A0A1F2WXA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium RBG_16_64_13|TrEMBL
MKIVEILNSRMSFSFEVFPPKTDAGMEKLREALKHFYSYKPDFISCTYGAGGGNAGRNVE
VCKGIKEDGVTEVMTHFTCIGNARGKITGEIEHYRSLGIENILAMRGDLPAGWEGTNGDF
SNADGLIGYIRQGFPDFCIAAACYPEKHILAPSFAADIAHLRSKQDNGAEFLCSQLCHDV
KAFKDFVYRIREAGITIPVVLGIMPALDKDAVIRMTVSNGCSIPAELATIIGRYGDDPDE
FKRAGIEYTINQIYRFMEAGIGGLHLYTLNKWEDVDAIMTGSGIRKDI
>A0A564VYA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia luti|TrEMBL
MKMKELFDRGEFAVSAEVGPPKGIHVDELVEEAKTYLTGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMFGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A8I0UCZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mammaliicoccus lentus|TrEMBL
MKMKEALKNRILIADGAMGTILYSEGLDTCPESYNLTHPKKIEKIHRSYIEAGADVIQTN
TYGANFEKLQIYNLEHRVKDIHKEAVRIAKRASNEDTFILGTVGGFRNIRKSDLSIESIQ
YHTEIQIETLVNEGVDGILFETYYDLEELLAVLKDTRAKYDLPIIAQLTASNTNFLRNST
PIPDALQSLLDAGADIVGLNCHHGPYHMIQTYKHIDIPKDAYLSCYPNASLLDLEENELK
YSNNAEYFSKSAKELVNQGVRLIGGCCGTTPEHIKKIKEVVKDLKPVHHKNVIPIETKKY
QKQDKQEPSITELVSHKPTVIVELDTPKHLDTDKFFKGVKALEDAEVEAITLADNSLASV
RISNIAAASIIKQNYKIRPLVHLACRDRNLIGLQSHLMGLSLLGINDILAITGDPSKVGN
FPGATSVFDVNSNGLAEIIQQFNQGINADGASLRRNSNFSVAGAFNPNVRRLEPAVKRLE
KKLDSGVEYFITQPVYEPEKIKEIYEATKHLDAPIFIGVMPITNYNNALFLHNEVPGIKL
SEGVLNAFEKVKHDKEATRALSISLSKELIDTIHQYFNGLYLVTPFLKYDITVELAQYSK
SITGTQSKEAIL
>A0A0S4IIW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bodo saltans|TrEMBL
MTKVIDAIKETIAAQRTFFALEYFVPLTNAGTENLYAIMERMCNCGPLFCGITWGDRGST
ADSSISIAGTGQTFLSLNMQVNITGYTSTPEEIRSWLSELKNRSGVRNLCVLRGNATGTA
KDGLVHFP
>A0A850BIJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polyangiaceae bacterium|TrEMBL
MQHPKGSAGGSDRPGPTSSPRTGRTFLEAVERAPVTLDGGMGTQIYERGVLFSINYEELC
ISRPELILSIHDDYIRAGAQVIETNTFGANRIRLSRHGLDDRVAELNLAAARLARQAAEG
RAWVMGAIGPTGLVFAGFSEDERARIRQAFREQAEALAEGGVDALMLETMRQPEELELAI
EGVRLALGRSMPLIAQVSVDENLALADGSDIALMGARLRDLECDVIGVNCSDGPQGVLAA
AEKLLQFGVPVSAVPNAGIPRRVDDRFIYVSTPEYFGVFARRLCKLGVRLIGGCCGTTPE
HVRRIAAAVRMAGCTTPSIVGEGGVDLGAPMWVGTGPSSEGEELRARSSATPAPPLVARR
EKSEFASKIGEKFVISVEVNPPTGLDPTPAIEAAKRLIEGGVDVINIADGARAQARMSNL
ALAVLMQRELGIETLLHVCGRDRNLLGQVAHLIGAHALGIRNLVVITGDPPKMGDFPDST
AVYDLDSVGILRLVSRLNRGIDPGGKPLGAATSFFAATGAEPAALNYTREMDRLAMKKRA
GAELVMTQPVYDTEVLERFLADAEPLGLPILIGILPLASHKNAEFLHNEVPGMQIPDDVR
ARMKAAGSGPEARREGVKIAREMLQAVRGRVAGAYVMPPLGRYEMALEVIDGFV
>A0A7K2E1T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MLSKLRRAPLSGETLGARHYRLHLVRDLTFEVIPLKSLDAAIEALPAGSRVSVTASPVKG
QDATCEITERLMELGHEAIPHVSARMVTDRARVSELAGWFRSAGVSTMFLVGGDVESPGA
YSDAASFLRDLLECDHGLSTIGVTAYPHGHPLIAEEVLHEALHAKQALLTEAGVEGYCST
QMCFDPERIEGWLRGERAAGLTLPVHLGISGVVDRAKLLTMGARLGVGPSLRYLRKNRAA
IMKLMTSPNYDPDHILMALSPSLDDLGVTGLHVFTFNQVATTVTWQSSHRG
>A0A7R8W6S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprideis torosa|TrEMBL
RLLVFRFDRMAMSGPLFIDVTWHPAGDPGSEKETSSMMIASSALNYCGLETMLHLTCCKL
SKSDITRYLTKAKELGIRNILALRGDLPADEESWRPSEDGCRYAVDLVRYIRQEFGNDFV
IGVAGYPNGHPEAESYEEDLRHLKEKVDAGGQFIITQLFFKAETFIQFEKDCRAIGITVP
IIPGIMPIQSYDSLRHIVKLSKLDVPRDLVEKIEPLKDNDEAIRDFGVHMAVNMIKKLFD
AKVAPGVHFYTLNREVATLEILKQLDLYSKADVSKRTFPWKMAANFKRCAEDVRPIFWAQ
RPKSYIYRTQHWDEFPNGRWGSSQSPAFGDLKDYYLFYLKSKSPKDELLAMWGSDIRSEK
EVWNVFARYVGGETNETGITVTRLPWNDEALAPETNLLRDQLVRFNKNGILTINSQPAVN
AAPSTDPIVGWGKPGGYVFQKAYLEFFACPQIVEQLLEILEDYCPRVNFHITDKTGATNL
TNAAKHRANAVTWGVFPGTEIIQPTVVDPDSFQVWKDEAFALWYEGWGSLYPANSPSRNL
LNEIRDTYLLVNLVDNDFVSNSCLWEILEKTLSRVNSKAAVTESAKALNGY
>A0A7X6RF16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium mucifaciens|TrEMBL
MFEDTPSTRLSASAPLDREGAPLIRRPRPKRQRTALSFEIIPPRPTDDSAKIDELIAGLA
EYNPDYVSVTSSRRSEWLEGTAAVISRIEETTDLRTIAHLACTAGTRDEIAEWVRVLIDA
GVRGFLALRGDLPETGLPADHLQYATDLLNLIQDVQEEEAFRLAGGKLALSVACYPKGHA
ESRNLDHDLDVLLTKQRLGADFAITQLFFEAQDFLEFVEVARLAGVRIPLIPGIMPMTSL
KRVKRMGELSGLEVPEGVEKQLRAADDEYEAGMQLTADLAREILDAGTGGLHVYTHNNLA
VTRDFLDRIGIDRGQQ
>A0A5A8CGR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cafeteria roenbergensis|TrEMBL
MAARIDELMAAHSGDAPWVAFEYYPPRTEDGVNNLKKKMPRFKAQKPLYIDMTFGAGGST
SDLTLDLCKEAKAAGLEPNMHLTCTNMPQEKIYEALEGAKAAGIRNIVALRGDPPLGQER
WEAVEGGFTCALDLTKHIVKTYGKDQFCISTAGYPEGHPGAIKKVAEGQELSDKEKRRVV
SLEDGDYVCSDADFAKEMEYLKAKVDAGASLIITQMFFDVDVFADFLEACKEYGITVPVI
PGLMLVQNAGGFGRMTAFCKTRVPASIREGLEAVKEDDAAVKQFGIDLGAKMCEQLMALG
CKGLHFYTLNLEKVTFGVMRKLGLFDEDAAAAAAAAAAEPAAAASAGAASA
>A0A7S0JTU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cafeteria roenbergensis|TrEMBL
ENLFLRIDRMSILEPIFVDVTWTTAGDGKDSRDGTFSVCEYAKQYAGLTPMLHLTLTGLT
RADLLRQLQRARDAGIRNILALRGDPPKGATEWRPCENGLSRAE
>A0A7S0JWE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cafeteria roenbergensis|TrEMBL
PGNKIIDRIREVHAAGGTTVSLEFFPAKTSKGVDNLLARIEGMTFRLRPTFVTLTWRSAF
TDELLWLRIGAHVQREFGIDVLLHLTCHLPVEDLKRVLRRCREAGIRNILALRGDPPIGQ
DKWTPCEGGLRNAVELVRLIREEHGD
>A0A7C3IIA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MSPPQSVDKESIAKKCGYFKGYVDAVNLTDNQTAIARMSSLVSSYYVLQGGVEPIMQMTC
RDRNRLAMQSDILGAYALGVRNLLCLTGDYQSFGNHPQAKGVFDLDSTQLIQMVKRMRDE
KVFMSGDEIKQEPRMFIGGAANPFGEPFEFRILNLAKKIEAGVDFIQTQPVFDVPAFERW
MGAVRDEGMDKQVYIIAGVMPVRSIKALLYMKESVPGMRISQEYIKRMESITDKEAAMEE
GIKIAVEVMKQVSKIPGVAGLHIMPVMWESVTPRLVEEAGFLPRPEVPSDESLGISETAE
VVGGEAEK
>A0A7S0JU46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cafeteria roenbergensis|TrEMBL
DDGDAAAAAAGSADGAEGAEGAGGAVDAAARDVADRDAAVAAAAAKVAAGAEVLLTQCVY
DVEAYSGFVAACRAAGVPESVPIVPGVLPVHGYEAFRRMTAYTGVNVPAELQDALDAAAV
SGDDEAVRREGTARVSALCRALLEAGAPGLHFYTLNLEMATRAILKDVGLCRGAEARRLP
WRPLGDGPGALTQVRPIFWANRHRSYVERTRNWDEQPTGRWGDGQSPAFGALSESHFGGP
GAAQGTSEERRAIWGEAEALDGEGPVLEVFARYLEGQVPRLPWCDQALLPETAPIRERLV
RLNRSGFCTINSQPRVNGARSDDPHVGWGGAGGRVYQKAYVECFCSPARLAALMEAAPAH
PSITFTAVDASGNLYTNCKRRGVQAVTWGVFPGKEVLQPTVVDEAAFLAWKDEAFQLWAS
VWADAYPEDSPAAEVLHGIATSWYLVHVVDHDFVAGDVFRPFEAATAALRIASD
>A0A4P6YJR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTATRLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKY
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
AALCERLIAGGAPALHFYTLNLAKPTTQMLQLLGR
>A0A2E6UNP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSDADASAPGRPGRRRSGRTTAKRATHRRLLEGMTYELIPLKNVHEQAAFLPAGSTVSVT
CSPAKTVDDTLDLCATFAGQGHTTIPHIAARMVEGEEHVDTIVRRVNEQGIRRVFVVGGD
ADPRGPFTDAAGFLRSFLDRRPDIDVVGVGSYPDGHSAIPEQALVDAQLEKQEMIREAGL
EGYMATQMCFDADTIREWLVRRREAGFTLPCHLGVPGAVDRTKLLTISIRLGIGHSARYL
KKNRTSVIRLLSPGGYNPNKLVAPLASVAEELDIAGIHCFTFNAVDTTEDWRRKSLKKLA
>A0A261G4X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium hapali|TrEMBL
MTTPMFSLEVFPPKRNAPVGTIYDTLDGLEGLKPDFISVTYGHGTASDRTATARIAHTIR
SEYGIPTVAHLTALYADHEIVDHALEMFDEAGVTAVLALRGDYLPDRETVSVFPHASDLV
AYIREQRPNLKIFGACYPEGHYESSSLDEDIANLKIKVDAGASHLISQLFYDNDDFYRFL
DKARAAGITVPIEAGIMPVRGPKSVRSMAERNASRIPEKLDRMLDKWADNPAALRAAGIN
YASEQITDLVAHGVDGIHLYTMNHPAGTRRIWSNVESLFAK
>A0A355DGA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MALADFGITQFFFDPSHYRRMADDLAALDCTTQVLAGVIPVTNPKSVKRFADMNGTHTPD
DLWNRLEAADPDERLRIACDQQAALIVDLVDLGVPGIHLYTLNVPEAVEGVLGRLGDGFF
AAAA
>A0A388P2K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSIFSSLKKSSVKVTPAVKTLVSNMRYELIPMKSIEQGILDLPTGAPVSVTCSPAKGIAA
TQEISARLIAAGHEVVPHFAARLVESREHVTKLASWVREQGIKEVFLIAGDAEKPAGPYQ
DGIELLRDFLDSNSGVSRVGFGSYPDGHAFISREALSTALYDKQKLLEEAGVQGLASTQM
CFDITQIRQWLKTERDNGFTVPIQLGVPGVVDRTRLMTLGVRVGVGQSMRYLSKNKTSII
KMLAPGGYDPTELVAGLAKDAQSLNIVGLHSFTFNSVADTAAWQREVLAK
>A0A5P9EMY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. THAF39|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRAEIGELLDLYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEDVVTEMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISDREKIAF
>A0A0Q9NV18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Soil763|TrEMBL
MATRITPAKNRAASLELIQDFSLEMTGKDVPALIEAKDHIPPGTRINVTFLGNEDLEMRV
AAAKAVRELGFDPVPHISARRLKSSGQLEEFLGRLQEVDASEHIFAVGGDPATPEGPYED
SLSVIQSGILQRYGVRDVGIGGYPEGHPDIAKDVLWAALQDKTAALAEQDLGAVILTQFA
FDTDPVADWIDAVRASGINSPIRVGTPGPAGIKRLLGFARRFGVGANAMIVKKYGFSLTN
LMGDAGPDRFVDDLAAVLADHTSGAQPHIGGRVGLHFYTFGGLLATADWVRRFVAEEG
>A0A3C2CHH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MKSTQLKLLDGMTYELIPLKNVHEQGEYLPKSSTISITCSPAKDIEATLELCESFLSKGH
TTIPHFAARMVESEEHVAQIVKRIESLGIETVFIIGGDADQRGPFNDAPGLLRSFLDKNP
KIKTVGIGSYPDGHPSIPESALAESLIKKQEMIYESNLNGYMATQMCFEAKTISSWLKNC
REAGVTLPCHLGLPGVVDMKKLINISLRLGVGVSSRYLKKNRKSVFKLLSPRGYNPNKLI
VPVSDYAEELDIAGIHCFTFNAVESTEAWRTKTMERLT
>A0A0R0C2M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas humi|TrEMBL
MTAISFEFYPPKTDDQRAQLDRTAAKLKVHTPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLQAAPHLSCVGGTREEIRELLKLYRAIGVKRLVALRGDLPSGMGFPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLRHFKTKIDAGADAAITQYFYNADAYFHFVDA
ARKLGVDVPIIPGVMPISNFSQLRRFSEQCGAEIPRWISKRMQAFGDDVESVRDFGADVV
ATLCERLISGGAPSLHFYTLNLAKPTHAVLQRLRSA
>A0A6B2C922|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurococcales archaeon|TrEMBL
MSCPKKMINGPCGGYNRSRCEDPRLECVWIKAFENLKKYGKEKDLFKLKLDSMFKIRDHK
PIKRDIREKLKIKDRIYLIYEYVASRDIDPRKLEKDLDHIFSTYDAIDFVQNPGGRPLPD
PLSLAVFTKKIYPHKHVGFQITGRDYDRDAITSIVASAVVFNIDSIIATTGDLKFHKEKT
YGVWDLDSPRIIYLTRLISDLGRDYSGRKILEKPREILVGASLNPYLDPIEPEIYKLNIK
KHAGADFFVTQPIFEPETYTRIMRLYKDLLNENDIPEIIPGISIISDIRIASFLIERSGV
KLPSKILEALKREDFSLIKETNIEFISDLVRKICMNYGKKIFYISTFGDIDMALEIGESI
KKMNC
>A0A3B0RS57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MLEQKLKKGDFVITAEIVPPLSGDRDDLFKRVAPLAGLVDAVNLTDGAGARLAMSSTAAS
ALLVAEGFEPILQMTCRDRNTIGLASDLLGASAQGIKNLLILRGDDPAKGDMPTAKAVFD
IESSELISMASDLQGTLGKKGREITSPPEFFIGCADAPHDPASDWQPDGLRRKIAAGAQF
AQTQFCFDIDTARNYFARLNDLGITQQLKFIVGIGPLLSLRQARFMNENLFGVTVPERTL
KRLEEAGDQKAEGQKICIELARAFKGIAGISGVHIMAPQQNGETIAQVVKSIRGF
>A0A3B0U574|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MNALREDSNPNDIDPTIPLPKLAGHVSHTRFERVLRAGQFAVTSEIAPPDSADPNQVLVR
ADLFNGVVDAINATDGSGANCHMSSMGICAILTRNGYSPIIQVSCRDRNRIAIQGDVLGA
AAMGVGSVLCLSGDHVSVGDQPGAKPVFDLDSISLIKTIRTMRDEGRFLSGRKLDKPPSQ
FIGSTINPFAPPYQNRVDQLAKKVRAGANFIQTQYCFDIEMLTSFMARAVDMGLAEKTFI
LVGTGPLASAGSARWLRANIPGVHIPDAVIDRLAGADKPREEGHKICAELMARIKEIDGV
RGIHVMAYKQEKFVKKIIRNSGVLGSRKPWERIISDFDRTKSQQVENDHG
>A0A1W1BX85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MFEKFCKKLHSNEPFITVEITPPHGASITKTIETIKSIGLDKKVSGFSVTDNPLAKLKMD
ATLSAIKVQRSFKKPVIATMSMRDKNKLSLQSTLLGANDFNLRTILALTGDPAKLSDQPE
VKGVLERDSTLLLSIIYRLNNGLDYNNKELNPKPKPIYPFAVSNAYSKDMRRIKKKILKK
LNYGARGIITQPVYDLDNAKELIEIFEECKKESVRETAKEAELILGQFPVVRAKTVNFIS
DRVPGITVPKDIIDEMNLAAMDGEEREQEIGFGISKTLFDNIMNLHPKVHLMTHNRFDLC
SKLIGDKV
>G5NKY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Inverness str. R8-3668|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1W7QUZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrifermentans pelophilum|TrEMBL
MGGSFLERVAHEVLIGDGAIGTMLYAKGVALDANFEHLNLVRPQLVLDLHAEYLAAGAQV
IETNTFGANYAKLSAIGIGGKVAEINRQGAILARRAANGRDVFVAGSMGPLGRGKQELND
EQVREAFLVQAASLAEGGVDLLILETFSELDELETALAAARQTGLPVVANLAFGEGSRLA
GGIEAEDAALRLAAAGASLVGANCGAGPLELLATLKRMAAVTDLPLAAYPNSGFPEYVDG
RYIYRTTPDYFAARAEEMVAAGAVLVGGCCGTTPEHIRVMAQRLKGARPAARVAVGAVSR
TPVAEKAQALGSSFLDRWGKEMVVTVELDPPKGLDCSRILAGSRALKEAGADAINLAENP
LARVRMGNLALASLIRREVGIEVIAHITCRDRNLIGLQSDLMGASLLGVSSILAVTGDPA
SLGEEAGASSVFDLNSFTLIKLLSDLNRGVNALGNPIGAGTGFTIGAAFNPNTQKMEVQV
ARLAKKVANGACFAQTQPIYDLERFEQMVEQTAHLGIPVLPGVLPLVGGRNAEFLHNEVP
GISIPDSIRERMAGKVGEEGVREGLAIAREFIEATMGRVGGYYLIPPFGKYEIAVELVKF
IKSRG
>A0A031LTS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. Ver3|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLADFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFQIEVAAYPEMHPQADSFDLDIKRFCEKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A3B0ZFX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MLMESQKKYPRVYSFEFFPPKTDAGAANLRVTRDELAKLKPRFFSVTFGAGGSTRERTFD
TVSEIQRDSGIEAAPHLSCVGSTKDSIREILDLYRKEHIHHIVALRGDLPSGMGQPGEFR
YANELVEFIRTETGDHFHIEVAAYPEFHPQAPNAQADIDNFKRKVEAGADSAITQYFYNA
DAYFNFVDLCEKRGIDIPVVPGIMPITNYTQLARFSDMCGAEIPRWIRKRLEACGDDMDA
IRAFGTEVVTHMCRQLLDAGAPGLHFYTMNRAGPTRAVWEQLDLD
>A0A1X1KCJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPEVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A4T0RBD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia mellicola|TrEMBL
MKITEKLLAAEREDRLWWSFEFFPPPRFVDLSTTISAHSVQGMTNLVDRIERMRRLGPEF
VDITWHSGGRTAELTTELVKTCQASIGVETCMHLTCTGMPREKVINALEEAKKNGCTNVL
ALRGDPPRGQTEWYPHPNGFTYAADLVRHIRQEYGDYFEVAVAGFPEGNLQYKHSSDKDN
EIQYLKEKVDAGADLIMTQMFYDVDNFIDWCNKVREAGVTVPIVPGIMPIQTWNGFQKGV
QMAQTKVPQDWMDQLEAVKEDDAKVREVGTKLVSDMCRKILDANVGIRGLHLYTMNLERG
PKMILQELNLIPQTQILNPLPWRPSLTPTRRAENIRPIFWANRQKSYLSRTEMWDEFPNG
RWGDSRSPAYGEIDGWGPTINFKLDEAREIWGEPLKYDDVCNLFSRFCLNDLKALPWSDQ
PPARETSVIDRQLAMMNKIGFFTINSQPAVNGARSDDPVHGWGPKGGYVYQKAYLEFFVS
PDNLDKLISRIELNPMMTYYAVNRRGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVS
FMAWKDEAFELGYQWSDIYEKGSTSQQLIKDIMDSHFLVNVVHNDFKNGQDIFKPFLDEI
ANESAIKDTTKN
>A0A1S7NYG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium deltaense RV3|TrEMBL
MPDISTASIIPASIEASPAQVLGSTDLAGLFPQGVRVYLTDTGAASQERLVEAAGHLRDL
GYEPVPHLAARRIPSRAAFEEQVKQLAGEAGVTDVLVVGGGVDRPAGPFASSMDMLSTGI
FDRCGMRQIAIAGHPEGSPDFNDETAMAALRLKRDFAERSDAVMRIVTQFGFDPARFIAW
AEGLAASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTTLAKGHSPES
IVGPIERHWQANPQGQIRQIHVFPFGGLQNSADWLVKRGSWQTGAVDSSASPDSMTG
>A0A081S8Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MQELAPHFISVTASNNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADL
DKVGVQKILALRGDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIVGACYPEGHPDSPNQI
SDIQNLKKKVDAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRL
LKTCENIHLPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNAET
AKYIHQATHALFNHQSLG
>A0A1W9XDP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_88|TrEMBL
MKSGSNLEKILTAGHFAFTGELGPPRGANVEAVREKAAPLKGMVDAVNITDNQTAVVRMS
SWAASLIAIQEGLEPNYQMVCRDRNRLAMQGDIMGAYAHGIRNMLCLSGDHQQFGDHPQS
KGVFDIDSMQLIGMVSQMREEGKFLNGQDIDTPPKMFIGAAANPFAEPFEWRVHRLAKKV
QAGADFVQTQCIYNMERFREWIRQANDMGLTEKIHILAGVTPMKSLGMARYMKAKVPGMD
VPDEVIKRLQAAGKGNYAEEGIKMACEQIEEFREMKGVAGVHLMAIEWEHKVPEIAERAK
MLPRPVV
>A0A1G3Y5D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfovibrio sp. RBG_19FT_COMBO_42_12|TrEMBL
MKAGSNLEKVLEGGYFAVTAEVGPPKGTSASVIRRKGELLKFYCDALNVTDNQTAIVRMS
SLSGSVILREMGIDPVMQMVVRDRNRIAIQSDILGAVALGIRNVLCLSGDHQKFGNHPDA
KGVYDIDSIQLVQTLKTMRDEKKFLCGEGISGEVLLFIGAVENPFADPFEYRVVRLAKKI
RAGADFIQTQAVYDVNKFSKWIEMIRDRGLDKQVHILAGIIPIKSVGMARYMRDNVSGVS
VPDEIITRLEGAKDVKEEGVKISLEIIDQLKGIDGIHGIHIMAVAWEDIVPVIVERAGLL
PRPVL
>W9PQC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. pisi HDV247|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A1Y4BQY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olsenella sp. An290|TrEMBL
MRITEKLARRQTFSFEIFPPKGEMPLESAYAVASEMAADRPDWISVTYSAGGSGNSANTV
PIAASIERDLGVTALAHLTCLGSSRADVDAYVASLAEAGVENVLALRGDRAPGRDPIDFA
HASDLIAYLRASGSELCIGAACYPEGHVESPDEEESYRALYLKQEAGADYLVSQLFFDNE
DFYRFREKCLRHRVRLPIVAGIMPFTSVKQIQRMAFTCGASIPAKVVKRLVLAGDDPADQ
ARAGLEYACEQLADLAANGVDGLHVYSMNKPSVAHAAREVLLACGYLGA
>A0A1S1QU06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. EUN1h|TrEMBL
MQESTAGHERPVRSFELICEIEPPTRPDLTXARHQIGVLSPVTDAFLIPDNHIGRATVSS
IAVAHEVQTMGGRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVHGDKPTAGNRTSDL
TVRAMMDEARAASEDPVFADMPAFRVGAAAGLRPLPTWKRAADFLFVQVSYSVDALLRWR
DAHPVELPIYAGVMVLASAGMARRLAATIPDIDIPDDLVQAVERDQAAGVEAACDQVLRL
RDSGAFAGVHLVPVSRYRQVATRLEDLL
>A6LUG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)|TrEMBL
MIKELLKNDILICDGAMGTYYSEVTGNDVSYCEFGNLNDKETIKRIHKEYIEAGAKLIRT
NTFSANTYDLGVSLETLMDIIKSGINLAKEVTRNTSVLIGASIGPIKTDNLDEFSNEVLE
EYKYIVDCFLKNGIDIFIFETFSNYNCLKKISEYIKYKNIDSFILTQFAVKPDGFTRDGL
SAAKLIKEVRNTKYIDAFGFNCGSGPAHILEMVKKINIENEIVSVLPNAGYPEIIHERTV
YPNNPVYFAKKVNEIRSFGVSIIGGCCGTNPSYIKQLTQIVNENSKVVNANAKAEPKVKS
FEKKAKNTFKDKLENGEFVVAIELSAPIDTDISRIIDGAKICKENNIDLVTVPDSPMSKV
RADSTIISSKIKREIGIEAMPHVCCRDKNTNAIRSSLIGSHIENIRNILAITGDPISDAS
KVETKSVFNLNSFRLIELIESMNEEIFKEDSIYVGGALNLNVLNKEVEYNRMMKKIEKGA
KFFLTQPIYDDNAIEFLKMIKERTNVKILAGLLPVVSYRNAMFLNNELPGVTIPDKYVQM
FSENMSKEEAQEIGVKITVEIGKKLKGIADGLYFITPFNRVNMLIEIIKQINA
>A0A8H8SCT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceratobasidium sp. AG-Ba|TrEMBL
MVFLRRLTPNGMKLVDKIAQHPPGAPYFSLEFFPPRTDQGFSNLLTRINGLSGLRPIAVS
VTWGAGGSTRDRSLELVGFCQADNALDTILHLTCTNMERGTVDDTLTTAMERGVKTILAL
RGDPPRGEEYWIPTDPRFQHAEDLVTYIKQHPVFSTHFCVGVAGYPDGHSEGGTEDEQLT
YLKRKIDAGAEFIVTQLFYDVDRFKVWLGKVRTRGITVPVIPGVMPLQTYAMFTRMTTLC
NATVPERLQADLNAIKHDDQLVKDYGVTLAVSMIRSILADGDVKGVHFCTLNLEKSVRKI
LDELGWTHVPTHTTNQIIIDSTQSPHVLPPPADSSHPITFTISPAEATQHATSTLNETRI
GASRAAAEALDRGWDDFPNGRFGDAKSPAFGNADPWDGGGLGVPPHAAVAQWGHPTSMAD
LTSLFLAYLQQKTPTTPFSPSPLSAESVSILAELISLTSRGLWTVASQPAIDAALSSDPV
VGWGPRDGRVFQKAFVEFFCEEQTLRKLIKLVEETGDGWITYFAGNHEDGFETNVPDGGS
NAVTWGVFPGQEIAQPTIIERDSFLAWKDDAFTIWNDFGLCYPPNSPSRRLVEEVTKTRW
LVSIVHHDYKNTDSLWKFLEV
>A0A846AAU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. SIO4C5|TrEMBL
MTAAQLSSPPASSSLHRFRQAAQAGQFLITAEVMPPKGGDPSHMIEMARCLQPRVHGVNI
TDGSRAVMRMSSLAAAAILLQQGIEPICQMACRDRNRIALQADLMGAYALGIRNVLALTG
DPVKAGDHPEAKSVFDLESVRLLKLIYQLNHGFDINEKPLTDRPTDLFAGAAVDPQSRSW
SGLQRRFERKLEAGAQFFQSQLISDFERLEKFMDQVAAGCDRPVLAGIFLLKSAKNAQFI
NRCVPGVQIPQATIDRLAAASDPLLEGMKIAAEQVQAARQLCQGVHLMAVRREDLIPQIL
DLAGVAPVKAIAETAS
>A0A4U8Z727|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocella tundrae|TrEMBL
MAEQPKRTRRTLIWNKEDVSRIFNSLQEPGPAFRLLRTPCSSYAYQQYDAVRRPDGALAG
LSTFVGYSANEAKFLSLAMMNLEDAEIGAELTLTWGETDGGSRKPQVERHRQTEVRVTVA
PASYAEAVRKMKYAAVASATRAGRPPSPGLIRGGPLPLRRRRRRRPRATWSSIDIKDLKA
PVFACRKYCARAVPASPRQKVEFQMRFETDVQGAADHGAYTGALKTLLGGYSVELTAADK
RSVDLALDILPKGTEVFVAALPNSKVADVVATAARLRRAGLTPVPHIVARNITDQRALRS
LLAQFAAEADIDRCLAIGGDRDRPAGEYSSSLQLLQTGLMHQFGIREIFIACYPEGHPKI
ADECLKDTRSRKLAIAARDGLKVTLLSQFCFDANPIVRFAETIRQESVTAPYRVGVAGPT
NRALLLKFALICGVGNSVRLLKGHGDLAAKTLSGETPEALLTEVADAAAANPALGISGIH
FFTFGSLAKSVQWAEQYGR
>A0A0A2INA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium expansum|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEAAENGFCYAKDLVKYIREKYGNHFDIGVGGYPEGADDNSDVDQLIDHLKEKVDAGSSF
VVTQMFYDADNFIEWVNKCRAKGITVPIIPGIMPIQTYASFIRRSNWTKVKVPSQWMETL
EPVKNDDSAVREIGKTLIANMCRQLIAAGIKHLHFYTMNLAQATQLVLKELDLSPSDESP
IQRALPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISDIFVNFLTGKLDRLPWSDSPITTEAQDIQEDLLK
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKNN
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCHDAASPSRKLIQHVMDDWYLVNIVDNDFHRSNAVFELFNDLEIKDLNVEVAGKPLTNS
HAEQNGVAAN
>X6FKD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNHC209A00|TrEMBL
MTGRQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDDITETQVDMVK
TAH
>A0A7I8CZG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solibaculum mannosilyticum|TrEMBL
MSIAQLFETKSTVFSFEVFPPKRTSPIETIYSTLDELQELHPDFISVTYGAGGNLADNST
CEIASIIKNHYHIEPLAHLTCVNSTEQEIKEVLGRLKQNGIENILALRGDISPDRPPKTD
FAHASDLISFIKKQGGFHVSGACYPEGHIECDSLVDDVLHLRQKVDAGAEHLVSQLFFDN
DSFYRFVERARIAGIQVPIEAGIMPVVNKKQIERMVSLCGASLPPKFTKVMSRYEHNPQA
LRDAGIAYAIDQIVDLVSNNVQGIHLYTMNNPYVARRISESVSSLLRA
>A0A7T7HAU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia sp. M8|TrEMBL
MKVTEHIAQSKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGEKYFEPTKGGNRYASDLVTQINDLGKGKFLHGEISGNDTNNSFCIGVAG
YPEKHLEAPSMQYDLKMLKQKVELGADYVVTQMFLDNQKYFEFVKLGREAGIDVPIIPGI
KPLAVKKHLQLLPQVFKIDIPEDLVNAVSQCKNNEAVKQVGIEWCVQQCKELLDFGVPAL
HFYTMGKSDNIQKIVSEFF
>A0A524KJM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MTDLNPRPSKAPVQVSFEFFPPKSPEMEATLWQAILKLAPLRPRFVSVTYGADGSTRDRT
HRIVSRIASETGLVSAPHLTCVGSTREEIKSIARIYRDEGIRHIVALRGDPPQGATRYEP
HPGGYPYAVDLVRGLREVADFDISVAAYPEGHPEAPDANFDLDYLKRKLDAGANRAITQF
FYDTENFLRFRDKCVARGITAPIVPGILPIAKFRQMLNFANRAGAKVPAWLHERFEGLDD
DPDTQRMLGASIAIDQVVTLRRHGISEFHFYTLNRAELTFAICYALGIRPQPASAEGAA
>A0A076F2L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus opacus|TrEMBL
MTRTPSIVDRIRSSSDGRVPFSVEFSPPRDEAAEARLWRAVREFERLGPAFVSMTYGAGG
STRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRGISNILVLRGDPPGD
PLGEWEKHPDGVEYAEELVRLVRDLGDFHVGVASFPEGHYRAPDLAHDTRYLVSKLRAGA
EYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSVRRVLELSGSSLPAH
LEKRLATAAGDGPEENRAAVREIGIDVATEMSERLIAEGAPGLHFITLNFARATSEVLAR
LGDKVGSGVADPAPVTSARVS
>A0A3M4PYU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas salomonii|TrEMBL
MHDLRFYEFPRVLTMSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGAGG
STRDRTINTVLQLESEVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSG
MGMASGELRYANDLVSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADS
AITQYFFNADSYFYFVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQL
EAYGDDVKSIQAFGEQVITQMCEQLLQGGAPGLHFYTLNQTEPSLAIWNNLKLPR
>Q0G0C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fulvimarina pelagi HTCC2506|TrEMBL
MEQTLWQSIERLAPLQPDFVSVTYGAGGSTRERTHQTIERILKETNLTPAAHLTCVDASK
EEVNEVVRQYRQTGVKHFVALRGDSQLGVGEEWHGHEDGYRNGAELTEGIKEIDEDIEVS
VSAYPEKHPESADLMTDIDLLKRKMDAGATRAITQFFFDNDTFERYVERVRKAGIYIPIV
PGIAPVHNFTKIASFAGKAGASIPDWVQARFEGLEDDPLTHSHVAAACCAEQVLDLSHRG
FSDFHFYTMNKADLVYSICHILGLRGRQAETPVALQDAAE
>A0A520WXD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
GASRGEIDDIAREYWDMGIRHLVALRGDAPQGAEHYEPHPDGYAYAADLVEGLKRVGDFE
ISVAAYPEVHPEAPDAQFDLDNLKRKLDAGASRAITQFFFDVDVFLEFRDRCAAAGIDSP
IVPGILPITRFPQLEKFAAACGASVPDWLSEWFAGLEDDAQTRQLIAASVAINQVRRLQA
EGITDFHFYTLNRSELAFAICHALGVRPHSVAA
>R5PEK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. CAG:487|TrEMBL
MLSRTDRRTFSFEVLPPLKGTGTGSLFSTIEKLKEFAPAYINITTHHSEYVYRETGGGLF
ERRRIRRRPGTIAVAAAIKNRFGIPVIPHVICSGATIEDIEYELLDLQFLGIDNLLLLRG
DKAKEDRNFIPTPNGHAHTTDLIRQVNMFNNGFFADGTPIKCPMGTFDYGVAAYPEKHEE
APNIEMDMKWLKAKQELGAQYAVTQLFYDNSKYFEFVRKARAMGIHIPIIPGIKPFTKVS
QLTAVPRTFRCDLPQELALEAVRCKSDDDARALGIEWTTTQCRELYAAGVTNIHFYTMSA
SDSVREIVSNIL
>A0A316RWV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriia bacterium|TrEMBL
MKISDKLAAHQTFSFEIFPPKGDLPLEKAYEVASALTTHAPDWISVTYSAGGSGNSDNTV
AIAGSVENKLGTTALAHLTCMGATGADVDAYAAALAADGVQNILALRGDRRPDRDVVDFA
HASDLIAYLRATAGDGLCIGAACYPEGHVESSSEDADFEGLYRKQEEGADYFVSQLFFRN
EDFYRFREKCLRHRIKLPIVAGIMPFTSVKQIQRMAFNCGASIPAKVVKRLVQAGDDPEA
QAAAGVEYACEQLCDLAANGVDGLHVYSMNKPAIAAAAHDALAGCGYLAK
>V4PEN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asticcacaulis benevestitus DSM 16100 = ATCC BAA-896|TrEMBL
MSPSLNPNLTSDLAPIARSLAGGGQNLKVSFEFFPPKSEEMETTLWESIRRLAPLNPEFV
SVTYGAGGSTRERTHRTVKRILDETHLKPAAHLTCVDASRDEVDEVIRGYWEAGVRHIVS
LRGDPPTGFGDYTPRADGYQNATELTAAIKKIGDFEVSVGVYPEKHPQSPSLDFDLDVLR
QKVDAGATRGISQFFFEPHTFLRYRDAVADAGIRIDLTPGIMPVTNYKGLRRMAAACEAA
VPGWMERLFEGLDDDAETRKLLASAVAVEMCLGLEREGVENFHFYTLNRADLVFAIGRIL
GLKESKI
>A0A1Z4KRX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichormus variabilis NIES-23|TrEMBL
MDDNHSYTALNYFSKAAQAGEFLVTAEVAPPKGGNPTHMIEMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQQGIEPICQMACRDRNRIALQADLMGAHALGIRNILALTGDPVKA
GDHPEAKAVFDLEAVRLLQLIRKMNQGVDCNDKPLTDGATDLFVGAAVDPQCASWSGLQS
RFERKIEAGAQFFQSQLITDFEKLEKFMDKIASTHKKPILAGIFLLKSAKNAQFINRCVP
GVNIPEHIIDRLAKAKDPLEEGVKIAAEQVQTARQLCHGVHMMAVKREDLIPKILDLAGV
APVNQLVAK
>A0A2V2ENW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriia bacterium|TrEMBL
MHIIDVFGGEKLPVSFEIFPPKGDLPVEEAREVIGGLAPLSPSFVSVTYSAGGSGNSSRT
IDVAKMAQDEYGLNMMAHLTCMNADRAGIDSVLASMKAAGIENVLALRGDAVPGATPKDF
KFAKDLIPVAREAGFCVGAAAYPEGHVDCLDFDESIRHLKEKQDAGAQFFVTQLFFDNEL
ALRFLDAARKAGITVPITFGIMPFLSKAQIQRMVFMCGASLPSPIIKLLAHYEDDPKALR
QAGIDYACQQFVGLSKEGVDGLHVYTMNRPDIAQAAVQALRDAGAIA
>A0A1W1YKZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocicer vacuolatum DSM 3385|TrEMBL
MRVATLYKNQTHPSISFEFFPPRDEKAEVEFTTVVDQLATLAPDYMSMTFGAGGSTSEGS
YQAVKMMKQEKKLPTVAYLAGFGLSPDSITTVLDRYKALGIETIFVLRGDEPRGSDFVPH
PDSFSYASDILKFISDRYDFDLGCAGYPEAHVQAESLEKDIEYLKLKQDNGAQYVVVQYF
YDNDFFYTYVDKCRAAGVTVPIIPGIMPIYTAKLTNMLCKLCGSTLPQGIKKQLDNTKNA
KEAAALGMDVAFEQCKDLLAHGVDGLHFYTMDRVPSVTRIVQRLREEKLIK
>A0A495D152|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maricaulis maris|TrEMBL
MSADGQTARNTNGLAVSFEFFPPKTDAMEATLWESISRLEPLQPDFVSVTYGAGGSTRDR
THRTVHRIVEETSIRPAAHLTCVSATREEVDTVIRDYWRSGVRHIVALRGDPPDAIGGAY
VPPAGGYANAAELSRGIRDVGDFEISVGCYPETHPESPNADFDIDLLKAKIDGGATRAIT
QFFFDPDIYFRFRDRAARAGITIPIIPGVMLQPNFKGLKRIAGLCGASLPSWLHEAYEGL
DDDAGTRQLVTAHVAAKLCGKLRTGGVDGFHFYTLNRAELALSTCQLLGVKACERESEAV
AS
>A0A6N9TI53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas genovensis|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASKDELRQIAQDYWDSGIRRIVALRGDLP
PGMDNTEMYASDLVALLKEVADFDISVAAYPEKHPEARNAQFDLLNLKRKAEAGATEAIS
QFFFDTSVFLRFRDRAAAAGVDLDLVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRGDSK
>A0A1I2R7R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium C7|TrEMBL
MLKKLENLLEGKDKDSQYFLFDGGFGTYYSEKYNDISSKCEMANITYSKRVLDIHKEYIL
AGADAIKTNTFGAFRDTFGDDCSNIIREGVALARQAILETNSEKTVRNIHKEIEIFADLG
PTPREIVSEQIQQYKEVVDIFLECGVSNFLFETLSDVQAVKEIAKYIKEKEKNSTIVVSF
GVMPDGYSREGFFYRDLLERAAYDKNIDAIGLNCVSSALHIYSLIRRLVKEYNFDIQNKP
FITMPNAGYPVVRGYRTFFDGNIDYFGEQLAKMLGLGVKILGGCCGTTPRHMMVVSKKIK
DKAKLNEEIAVLDNDKKEEKKNEGKKITENYQGFDYSKKVIAVELDSPKNDDLTKFMDGA
KRLKKAGVDAITIADCPIARPRMDSSLLACKVKRELGLDVIPHMTCRDRNINATKALLLG
ISAEGIRNVLIITGDPIPSAFRDEVKIVYQFNSRKLARYVNSLNNELLQGKINIYGALNV
NARNFDVELSRAKQKMQEGVCGFLTQPIITENALNNLKKARTELAGAKILGGIIPIVSEK
NARFMQSEISGIDVDDATIERYVGKSKEEATKLAVEISEEIAYKIKDYVDGFYLMTPFNR
VSIMVDIIDKIKNIK
>A0A7C7VN87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteriaceae bacterium|TrEMBL
MSVPLAHLLNKAMQERLALKESGGGASSLERTFIFTFELVPARASRSKAINEILLFAEAA
SRGGLIHALSITDNAGGHPALAPASLGKEIKGMGIEPIIHFSCKDKNRNMIESQLFELDR
AGIRNLLILTGDYPSSGYQGIPKPVFDLDSVHVLEMISTMNRGYGLGSRHGVSATRLPPM
DFQHGCVVSPFKRLKSELVPQYLKLKRKIMAGAGYIITQMGFDARKFDELRIFMDTNKLS
VPLLGTVFISDIRLARIISRGKVPGCMIPARLLSRMEAESTAYDGGLSARLERASRLVAV
LMGIGYEGVHLSGPGLTYPEVAQVIKKSRKLAPLWREIVSEFLYPEEWRFWYYKKNPETG
LNTTEAEAQSRSKLSFMESLHMRVGCMVHNMAFIPGKGLYSPLSRMAERIHGSTFENSFT
ALEYMVKSWLYDCRHCGDCTLGELGFLCPQSQCAKFLLNGPCGGSTDGWCEVWPGKRRCM
YARIYDRLTCTGELFRLESNPMPPRNWGLYNTSSWINFYLKKGKRAEGAESNGLTGV
>A0A1F2Y1N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium RBG_16_68_12|TrEMBL
MDRFLERLHSGLPIVGDGGMGVLVSSAVSRLRCPEEANVRAPESVLSLHLGFIRAGADLI
ETNSFGANRPKLRGHFLEDEVKAINEAAVKIARDAREVSGRDVLIAGSIGPLGEIGDLDE
ERGSFFAEQAELLEGRGVDLFMVETFYDLDELLTAIGAVRAVSSLPIVALLTFDEDAQTL
GGVTAEQAAAALADQDVAAIGANHGLGLQAALRAIEQMRGNGKPLAAMPNVGLASLAGQR
IIFPHATPEYFGDFAAHAQALGARIIGGCCGTTPTEIAAIRGAVDEQRRPSAPMVVRERE
LVVAAPEPQRETLLQRKLHAGEFVVSVEIDPPRGGNAHAMLEVAQALKESGHVDVVDVND
NPRARARMSGLIASSTIERVIGMETIPHLTPRDSSIAGLESMLLGAHAEGIRNVLAVTGD
PPEAGDYPGAQGVYEVDSIGLSRIITRMNAGEDFNGREIDAPTSFFLGVAVNPAADDLEY
ELERFEQKLEAGAQFAMTQVLFDLDYLDGFLERLG
>A0A8J3CUF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mongoliitalea lutea|TrEMBL
MKITEYIAQAEKTLFSFEILPPLKGQSMQDLCDGIAPLMEFKPPFVDVTYHREEFIYKKH
PNGLLERVATKKRPGTVGICAAIMNRFHVDAVPHLLCGGFTKEETENALIDLNFIGVQNV
LALRGDAPKTANKFVPEEGGHAFTKDLVKQIIGMNHGKYLHEETETSFHTDFCVGVGGYP
EKHFEAPSLRTDLKYLKEKIDAGAEYIVTQMFFDNEKFYEFVRKVREMGIDVPIIPGLKP
ITTLGQISMLPRTFFIDMPDALMDELEKCKTNADVKQVGIEWAIHQSKDLINNGVQVLHY
YTMSKAEATYQIAKEVF
>A0A484NFK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cuscuta campestris|TrEMBL
MKVIEKIRELSKEENNGGKVVFSFEFFPPKTQDGVENLFERMERMVAHNPTFCDITWGAG
GSTADLTLEIASRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPH
GQDKFVQVEGGFSCALDLVKHIRDKYGDYFGITVAGYPETHPDVIPASGVATPEAYQNDL
AYLKRKVDAGADLIITQLFYDTDTFLKFVNDCRQIGITCPIVPGIMPINNYNGFIRMTGF
CKTKIPPEIMAALEPIRDNEEAVKAYGIHLATEMCKKIIASGIKTLHLYTLNMDKSALAI
LMNLGLIDESSISRSLPWRRPTNVFRTKEDVRPIFWANRPKSYISRTIGWDEYPQGRWGD
SRNPSYGALSDYQFMRPRARDKRFHDEWVVPLNTIEDICELFSKYCLGRVRSNPWSELDG
LQPETRFIDEKLADINKKGFLTINSQPAVNGAKSDSPSVGWGGPGGYVYQKAYLEFFCSR
QKLNALVEKCKSFPSLTYIAVDKEGTWISNVKQTDVNAVTWGVFPAKEIVQPTIVDPASF
MIWKEEAFEAWSKCWGHLYPESDLSRKLLDEVESTYFLVSLVDNDYISGDLFGIFNDM
>A0A1V5PB13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin356|TrEMBL
MLKNNRATVSCELFPPKDEWNMERAEALVGATAAFNPDFISVTCGASGSNSKNTLAMAEC
IKQSNAVALAHLTCVCCSKDEVLGLISRLKEAGIKNILALRGDIPQGYALTGNSHFKYAS
ELVDVIKNFGGFSIGAACYPEGHVSSANQQEDLLHLKEKADAGCDFLTTQMFFDNNILYR
FLYKIREHGINIPVLAGIMPVTNKKQISRIVELSGTALPPRFLSILDKFGDDQKAMEQAG
IAYATEQIIDLLANGVRGIHIYTMNKPEIAKAIMQNISFIIQQVRLCG
>A0A1F2XNV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium RBG_16_68_12|TrEMBL
VTTSPNKGLEPTLALAERLTGQGYAVVPHLSARLVRDRSHLAELVERLRASGTREVFVIA
GDATQPAGEFAGAAALLRELADLDHPFAEVGITGYPESHPIIPDETTIQAMFEKAEFATY
IVSQICFDPQVTVAWVEAVWKRGTRLPIHVGLPGAVPRTKLLRVSARIGLGESTRFLRQH
GSWLTRALRPGGFSPDPLIAGFEESLLDPERKIAGFHIFTFNDLADTERWRQQTLERHRN
ER
>A0A0R2Q8N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium BACL2 MAG-120813-bin23|TrEMBL
MNSAPTFSVEFFPPKDQAGEERLWSALKALEVYKPDFVSVTYGAGGSTRDRTIRITSEIT
ARSGLSTIAHLTCVGSSRDELIEILSQYKVSGIKSILALRGDPKGGPGVKWESTAGGFDY
ADQLVLLASSMGFEVGVAAFPDGHPASKGNFEQDIKVLLEKERCGASFATTQFFFDVKGY
INLVNQIRAKGSKLDIYPGILPITNFAQLKKMSELAGSAIPIEIQRRVEAAGDSPEEVVK
VGIDIASELSKDLLDYGVPGLHFYTMNSAAPTIEIIRRIGLR
>A0A4R2Y7V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. JUb134|TrEMBL
MTISVNQLEEARRALDAPLFADMAGDAAVSFEFFPPKSAKMEETLWEAVRTLEPLGPRFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEASRDEIDQVAEEYWAAGVRHIVA
LRGDPPVAGQKFQAHGEGYANAAELVAGLKKLHPFEISVAAYPECHPDSGTKVEDLDNLK
RKLDAGATRAITQFFFTPEAFFRFRDAATAAGISAEIVPGILPVSNVAQTRKFAGMCGAA
IPDWMDRLFEGLDDHPASRQLVAATIAAEMCRRLYAGDVRHFHFYTLNRAELSYAICHLL
GLRPNKAAGAVAA
>A0A235AMJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. N4311|TrEMBL
MTIAPQSEIREKAPLADLLSHYSIEVTSRDLSSLQSMTATLRPGSEVFIAHLPKEDIGLL
VRAAAGLRDAGFVPVPHIVARNIRNRLELDTMLARLSEEAGVRHALVLGGDRDDAAGAFG
SALDLIETGLFQTYGVGRIAIACYPEGHPRIAGAVLDTALTAKVDAAARAGLDVLLVSQF
LFDPQPLLSFARRLRERGVAAPLRVGIAGPASRTKLLKYALRCGVGASLRALRERSEIAR
NVLSGETPEELLIDIAAAQAAEPDLGIGGAHFFTFGDPAQSIRWAEQQEASD
>A0A533TXT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium sp|TrEMBL
MLVKEILASASKPVFSFEFFPPKKDDDWETLFETIAALSPLNPSYVSVTYGAGGSTRSRT
HTLVTKIQQETGLTVVSHLTCICSDTEETGTILQNYQENGINNVLALRGDKPSGMATIEE
AIKDFPYARDLVRFIKCNYPDIGVGVAGFPEGHPETPNRIKEIEYLKEKVDAGADYIVTQ
LFFDNRDFFDFVERCQIAGINVPVIPGIMPISTKKGMIRMSELALGARIPAPLLKRVLDA
ESDADVASIGIEWATAQVQELIDHHIKGVHFYTLNMADATLRIFRNLHP
>A0A4V2Q8M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerospora hongkongensis|TrEMBL
MSEQLTKELTTESRLEKGFARGEFVVTSEIGPLKGASAHNIIEHTKEAKLKCDGFNLTDN
QSAVVRLSSIAAAVHVLQHGGNPIIQMTCRDRNRIAIQSDLLGAYSLGVRNVLCLSGDHQ
SFGNHPTAKNVYDIDSIQLIALVKKMRDEQQMLSGEAMKAAPRFYIGAVESPFGDPIELR
IMRLAKKVQAGAQFIQTQAIFDIEKFKYWMSLVRKAGIDRQVNIMAGVLPVKSVRALQYM
KENVAGMSIPDELIDRMAKAENPQTEGIAIVIELIKQLRQVEGVKGIHIMPVGWEAALSD
IVTGAGLLPRPILD
>A0A5S4GQ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea zeae|TrEMBL
MPFELICEIEPPTKPDLKHVRHQIGTMSKIAHSFLIPDNHIGRATVSSVAVAHEVEAMGG
RGIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPTVGSRTSELTVRSMIEEARAF
SPDLRLGAAAGLRALPAWKRTADFLFAQVSFSVEAQLRWRESHPVDLPVYAGVMVLASER
HARTLAASIPDIDLPEDLIDRVATDRMAGVEAACEQVLALRDSGAFAGVHLVPVSRYRDV
ESRLAAALG
>A0A4R0FLZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4173|TrEMBL
MSKNIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDLDIQRFCDKANAGANAGLTQFFFNPDAYFYFV
DRIQKQGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A850CBT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycomyces artemisiae|TrEMBL
MTLGTPSVMPVKAAKIGDLLRSGEPKFSFELFPPRDEAAEGVLWRTIRDLERLGADYVSV
TYGAGGSTRLKTVDTTNLVNAETTLLTMAHCTAVDHSVAELRNLIGHFANVGVRNILAVR
GDPPGNPRADWVQHPEGILHARELVELIKESGDFSVGVAAFPDGHPRDVDWDTGVRYFVE
KCRAGADFAITQIFYDVEDYLRLRDAVAAAGCDVPIVPGIMPITNIKQIERFAVLTGMVF
PEALAERLRAVADDRDAVRDIGVEVATAMGARLLEEGAPGLHFTTLNHSRSTRRVWKNLR
P
>A0A381W0T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MTTLVELVAKNNQKPFIVCDVSPPRGGSTRLLDGITDLTPDMFFVAANPGRAVRASSSSV
AQWIESNTKIPALFAMTTRDMNKTAMQTSLLGAHVMGLRNLVVVRGDNFTVSRGCADASV
KGFTPTEFIRSVKNLNKRTDFTGRVLSEPTDFCVGSTLDTSRDWGSEISLTANKIRCGSD
FLIAQPNFDPVVTEQFLEQYQGNQKSELNVPIMWGVQIMSRDSISFTDVPEKVTKELALG
SAGYEIALDMIHKYLEIGIKDFYLVPPIFPGGRRDYESAQAVIEEL
>A0A838KR67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MVIGRPATSVRHLLERPGPSFSFEFFPPQDDEGERRLWQAIRELEPLRPTFVSVTYGAGG
TTRDRTVRITGRIAGETTLIPVGHLTCVGHSRDELRAVIGAYADAGVRNMLALRGDPPGG
PGNPWTAHPEGLDHADQLVALVRSHGDFSVGVAAFPEGHREARSLEEDARVLVAKEAAGA
DFAITELFFRPADYFALVERSRVAGTRIPIIPGIMPITNLKQILRFAELSGRPVPAEVVA
RFDGVSEPSDVRRIGVEIATEMCNELLSKGAPGLHFYTLNRSTATRQIFANLVQG
>A0A151E5X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon SG8-52-4|TrEMBL
MNFRSNLERVLSEGKFAITAEIGPPKGADPNKIKEKAEILRGYADAYNITDNQTAVVRLS
SMGGSFLLLNLKLEPIMQMTCRDRNRIALQSDVLGAASIGVRNILFITGDHQSFGNHPDA
KGVFDLDSIQLIQIIRNMRDKGIFQSGDKILSGNPEIFIGAAANPFAEPYELRVDRLEKK
IEAGADFIQTQSVFNLDRFNGWMDEVRSRNLDKKIHILAGITPLKSLKMTERMKFHVPGV
DIPDRIYERMKKASDPKAEGYNLALELINDIKKIRGVHGLHITALFWEDVIPHLVMKSGL
LNR
>A0A523W7G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium|TrEMBL
MEADDYISISGDDYVSLSHLVESVGLREKLNTKLRERVNTLREAILDPDTFCITWEQIPG
RGAFEIQQEEIIENVEKAAKGEAIHAISVTDNPGGNPALSTEMLCAEIKKLEIEPLVHLA
CRDKNRNEIESMLYGLAAAGVRNLLVLTGDYPSNDAFKGRPKPVFDLDPVHVLQLAEMMN
KGLEHEVMRRKRTLAPTDFFAGVCVAPFKQLEAELMGQYNKLRKKIEGGAKFIITQVGYD
ARKFHELLLWLRINGYDIPVLVNIYIMPYGTARLMNDNQIPGCVVTDKLLAEVAEEAKAE
DKGRSARLTRAAKMYAIAKGMGFAGAHIGGHGITYEAVEYVIEKGEELSKDWESLVAEFD
YPQRNGFYFFEKDTKTGLNLDKPAARPSKFSLQLMYRFCRVAHALLFEPKSPSFKMLKPF
ARLMDSSPTSKKTFGYFEHLLKVALFGCMNCGDCALFDVAYLCPMSRCPKDQRNGPCGGS
YEGWCEVYPNERKCIWVRAYERLKAFNEEDEIGAYVVPPCNWELWETPSWLNFYFGRDHT
AIRLGIETQQDGASLEKSSIATSEIPSSG
>A0A382L8R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MAKVTDILNNSNEPVVICDFSPPKGSDPYLQYNAESLDATFLCTAYSPGQSVRVDPAMLA
YTIKKLTQKEVIFTLATRDMNKLAIQNHLLGANLLGLENVLIVGGDAFSKSDSTSVKSVK
DFTTTQLIAATKSMNLGKDYRGRELLSPTNFCVGATIDLGNNLQKESILTHKKVTAGADF
FVTQPIYDTETLERFQDNYSLLNERFTRPFFVGLQIL
>A0A381UPX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MNISTKLDEYNNQGKTFYSFEFFPPKTDFGLDNLYSRIDRMASLGPAYIDITWGAGGSTA
DKTFEMSKTIQKYFGLDVMMHLTCTNMPSDSIKKILSDAQKNNISNILALRGDPTDGSSA
WKKNDSGFNYGADLVKFIRKEHGNNFFLGVGAYPETHQEQKNADLDISYLKEKVDAGADI
IVTQLFYDVEKFLLFRDKCSQAGINIPIIPGIMPIHNYARFIKFTQFCKVSIPNSVSDAL
ELIKNDDSSVIDYGIEQASNMCEKLIEEGVPGLHFYTLNLEHSVTEILSTLGLASTHKSN
RVLPWRQSTLDQRKLSEDVRPIFWSNRPVSYLTRTETWDDFPNGRWGDISSPTFGELNQY
HAIRAGSQSDKVKARRRKLWGEPISIKNISDVFVSFCKGKINSLPWCETPLAIESKQILD
DLVALNQEGYFTINSQPKVDGLPSDDPNFGWGAKGGKVFQKAYLEFFTSKDNLDRLVLRL
DELNDISYQALNFDGDLISNLPENNVNAVTWGVFPGQGILQPTIVDARSFLIWKDEAFGL
WINDWASIYKTNSDSYNLIHQIHDTHYLVNIVDNDFIDGNMIKHIIEK
>A0A7C7KSD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquificae bacterium|TrEMBL
VYGAVYNPYSGPKELQERKLEKKISLGATFIQTQPIYSIKIGKETLKLISNLNAYPILGI
LAINSRKMLEFLEDLLPGAIDESLKRHLLSTQNIKEAYFEYLEDFLKAFRGEDVGFHFMF
FKDIESLTKLLEKVF
>A0A382FH50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MEYQSILHKKLLDGNFVYTAETTPPDSSDQEVLLKKIKSLKNVADAVNLTDSPGAKVHMS
ALTAAIILIQNGIEPILQLTV
>A0A382JKY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MGRLAEALKASPFVITGELTPPKGTDLGDLFTKAELLREHVTAFNLTESHAARMAMDPVA
VGHLLIDRGVEPIVQMTSRDKNRLAIQASILGAAALGISNVVFMGGDPPKNGDHPDAKPV
FDLFASQLLEAASALNAGNDLTGNPLKGVPQLTIGAVANPGANDIDTEIDNMKRKADAGA
EFFQTQAVYDTEAFGRFMDRAKPDKTVLAGIIPIKSVKMA
>N9RTH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 542|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASES
YPNSIDKVLHFSGKARDIQDFERFLQQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAIMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
TGKEFSPEISRFSRQPTSKQMIKYRQLHVLHEAMFESKIAKGFGRFIFKASFWENTLVAK
LLLKTEVLSKHSLVGCENCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKALEQTEILKEKLIPTVAIETRGTSSWKNWYLATEA
>A0A382JXV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MSIPETNNQAYTYRPGELLPELEGHISRGRFERVLRNGDFAVTAELAPPDSTDRNEVFEQ
AALFDGCIDAINATDGSGANCHMSSVVVCALLSYIGYSPIMQISCRDKNRIAIQGDLLGA
GALSICNVLALTGDDVSVGDHPEAKRVFDLDSISLITLIKKIRDEGSFLSGRTITNPPQM
FVGTSINPFVPPVESKILQLEKKINAGADFIQTQYCFDMPMLKDFMSKTVDKGLTEKAFF
>A0A381WAA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MRFRDKVKKPRRPVVVYEILSPREQDGTLSSYAERISSLLSQTHIDAINIPEVHDEEGRG
SRPVQNQLRAEPREFGRLLQDNVGVEAIVNRVVVHEKMATQQRWLKETYYDYGIDNLVIV
GGESHENSYSGPGVNEASRYITRELNGNRFDYFCGGITIPSRKVESQRLLEKSRHGIEFF
TSQVLYDSRKIRKVLERYQQRCDADGMFPRRILLSFAPVSSPKNIEFLKWLGVEIPAKTE
KYLLEAPDEMGQRSTEIASGIMREILEYISEAELRVPIGLNVEHIMSYNFQASITMLQEL
ARDYREFCIRTNLYG
>A0A6G5QWJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. RM6914|TrEMBL
MLVDKILQNKQGIMLYGMTPPRDNVELSEKERLGTLHRERVQSIGCDGVVLYDIQDESDR
NESDRVFGLIEPIVPEIYYRDWMRTSVPAVIYKVVGKYDRAEFEKFINELSPNSICVFVG
ASSSSKQVKIHLNEAYEIAKSRTDIVYGGICIPERHITKGDEHLRVAQKIQQGCKFFITQ
AVYDDKNAKKFLDYYAKLDAPKVPIIFTFTPCGSARSLEFMKWLGIEISPKTEQELLGAQ
DMLAHSMKHSAKLFGELYEYGKRLGISIGANVESVAKNKTDIAAAVTLFSSLKTMI
>A0A366VYR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loktanella sp. D2R18|TrEMBL
MSNTTVSFEFFPPKSLAASFRLWDCVNTLAPLDPTFVSVTYGAGGTTRKLTHEAVGTIHK
TSGLNVAAHLTCVDATKAETLEIAEGYAQEGVREIVALRGDAPKGADGFTPHAEGFASSV
ELIGALADTGKFNIRVGAYPEKHPEAVDQAADIAFLKRKIDAGATSAITQFFFEADTFFR
FRDACVKAGIDAPILPGILPIENWAGTQRFAKMCGTTIPQVVTDAFENATRDGTTDLLAT
ALATELCDDLRQGGVEHMHFYTLNRPELTRDVCHALGVTPKASLQNVA
>A0A3D3KI66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTFDELNKLSPTYFSVTYGAGGSTRSRTLNIVQALCA
RGDTDIAPHMSCIGDDKSEIAELLELYKGLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFEFDVDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTTAQPLVAGIMPITNSSNLVRFADSCGADIPRYVRKRLADFGDDSKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLTA
>A0A1X7I3V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agreia pratensis|TrEMBL
MESLLSPRAAHAGCPKNMEYGPCGGVGFDESCEVGDFRCVFLGDPLVTWHGGAPAEFDAV
PRSSGALEMMALMNTRPIVVADFPAKALDAESLAECAALLAGPVDAALAGDVGHARVQFS
PSYRASLIRAAGLEVWTGINCRDRNRVAIEGELAGLAQVGVAGVHCVTGDHTLLGGRPDA
APVFDLDSTQLAALARAAGHLVSVGESPTTPPVELRAARLLEKTRAGADVCFVNHSGGVD
AVGRFVRESHDLGVTAGFIPCVPMVTDHASARLLQSFPSLVLPEGYLEGILSAADPREEG
IRAAVELSLELLEIEGVAGVNLSGGAGVGREMEFAIALAETAERLAL
>A0A5E4RUZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea horticolens|TrEMBL
MSGSLDNKTIMTQPSFSFEFFPPKTADGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQG
TLDTVIEIQREGVEAAPHLSCVGSTKENIRQILETYRANGIRHIVALRGDMPSGMGEIGE
FRYASELVEFVRAETGEWFHIEVAAYPEYHPQAKSPRLDLEHFANKVKAGANAAITQYFF
NADAYFRFVDDASRLGVAVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
EAIRAFGLDVVTALCERLLAGGAPGLHFYTLNAASATKTMWQRLGL
>A0A653VLF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. 8M|TrEMBL
MSFDVPPFAPHGAVAPRVPISFELYPPRTPAPVEALHETIQQLASVSPRFISVTYGAGGS
VGGRSLEVLRYIREHTAVEPLAHLTCVGSTYAGASRLIREFLDAGILSFLALRGDPPLGE
TEPFLGDLESSAQLVQLIDRAQAERAPYQERPIPGVPGAVQVTPRRKVNIAVAAYPNGHP
RSTYRNQDIDALLAKQAAGATLAITQLFFHPDDYFAFVERARRAGVTIPILPGIMPITSP
ARLRRVLELSGEELPAELSIALEVEPTAEGRTEIGVAHAAALVRELVEGGAPGVHLYAFN
QHRTVLDVLDEAGVLAPSASSRIDRPSAMPTVRR
>A0A1W7D3T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SCSIO 3032|TrEMBL
MALGIASRMYGQAQTVRELLAAGERSFSFEFSPPKTEQGERTLWNAIRRVEAVGPTFVSV
TYGAGGSSRERTVRATERIATETTLTPVAHLTAVNHSVAELRNIVGQYADAGIRNMLALR
GDPPGDPMGEWTRHPEGVGYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWETDVRHFVD
KCRAGADFAITQMFFNPDDYLRLRDRVAAAGCDTPIIPEIMPITSVRQIEKFTQLSNATF
PPELESRIRAAGDDPMAVRSIGIDFATELCGRLMSEDIPGLHFITLNTSTHSTATLDVYR
NLGLHQRT
>A0A1Y0LP64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tatumella citrea|TrEMBL
MSFFHANQYEALNQSLSELNGRIHVSFEFFPPRTQEMEDILWRSIDRLSILKPQFVSVTY
GANSGERERTHNVIKGIKERTGLEAAPHLTCIDADRNELQLIARDYWQNGIRHIVALRGD
LPDNSGKPAMHAADLVALLKGVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGADRA
ITQFFFDVESYLRFRDRCAAAGIEVEIVPGILPVSNFRQLQRFSALTNVRVPHWMSSQFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPQGVAA
>A0A316KQ69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marivita sp. XM-24bin2|TrEMBL
MPAPSVSFEFFPPQSLEASFRLWDTVQVLAPLQPRFVSVTYGAGGTTRDLTREAVATLHK
SSGLPVAAHLTCVNATRAETLAIAQDFSAAGVTDIVALRGDPPKGEEGFVPHPDGFASSV
DLIEGLRDAGDFTIRVGAYPDIHPEAADAQADVRYLKRKFDAGASEALTQFFFEAETFFR
FRDACEKAGIDKPVTPGILPIENWKGAVRFAQRCGTYIPAWVVDAFEKAERDGREDLLAT
AICTELCSDLIDGGVDTLHFYTLNRPELTRDVCHALGVTPKLDLKNVA
>A0A2E7KZY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MHITDIINKGRPTFSFEFFPPKSERASESLFETIKDLESLAPSYVSITYGAGGTTRERTH
DLVEKILEKTTLIPIPHLTCVQHTEEEISNILKRYSDKGISNILALRGDNPKGDAQYDRS
KDSFCFARDLVEFIRNFDNSTLNKKSKSFGIGVAGFPEGHPETPNRIKEMDHLKAKVDSG
ADYICTQLFFDNHDFFDFRDRCELAGINIPIIAGIMPVTSISGMQRMADLAAGSRFPAKL
LKSIDRCNLDSSAVERVGIQYATEQCSDLLNNGVDGIHFYTLNKSKSTRGVFEALGINKT
>A0A2D7DXK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MKQSKVNVSFEFFPPKNEGAISSLWHNINRLEPLKPRFISVTYGAGGSTRENTHDLVKQI
KKKTNLQPAAHLTCINSTKEEIESIANDYWLSGIKHIVALRGDLPKNNDGIKSDFKYATD
LISFLRKKYDFEITVSAYPETHPDSDSMEQEYDILKKKIDLGATKAITQFFFDVEYYFKF
IDGAVKRGIRIPIIPGILPVTNCKRTIEFAKKMNCKMPKKLKNMFEGLDSDNETRKLVAA
TIAYDQCDKLIGGGVKDFHFYTLNRADLSFAICHILGVKPKAQI
>A0A497E189|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium|TrEMBL
QSSVMRLGSLAVCHLLAERKLEPIFQITCRDRNRIALQSDLLSAYVLGIRNVLVLTGDHP
VLGDHPEAKPVFDLDSVSLLKVASTLMEGKDMKGNELVGKPEFCLGAVVNPGADIMELQL
IKMEKKIEAGAKFFQTQAVYDLDSFEKFMKEAEKFGVPILGGIVLLKSAGMARYMNEKVA
GVSVPERYIKMMAKAKKGERAEVSIKIASELIKGMKDLCQGVHIMPLGWGKYVPRVLEAS
NLLGSKE
>A0A4Q2XKA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
AQCADLLNHDVAGLHFYTLNQTDAVLKICERTGLANHPQATCA
>A0A520LED4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MAILSSLRASRPTLSFEFFPPKNNLGSEELLETVNELGKLDPAFVSVTYGAGGTTRERTR
EVVQRIIQDTNVPTIPHLTCVGHTKSEISEILSQYSADQVGTILALRGDPPRDQPNYDRE
GDDFKFAGDLVAFVKENSNEFEVGVAGFPEGHPETQNRLTEMDYFKSKIDQGADYICTQL
FFDNHDFFDYRERCNLVGVDLPIVAGIMPITTISSMKRMADLAAGSRFPAKLLKRLSVAD
GDAAAIRQAGIDHAIEQCQELIEQNVSGLHLYTLNKSSATREIANALTF
>A0A2N8K6Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. M4_45|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYERAAVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGVG
PMASAKTARWIRSNVPGIHIPDSIIKRLEGAQDQKKEGKQLCIDIMNEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLRGRKPWTREAAPTDALVAERLEHIREGKEENQQQMAEAAAH
HPH
>A0A6I7SUD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus paralicheniformis|TrEMBL
MSFLEDIKRKTLIADGAMGTLLYSYGIDRCFEELNISKPDEVKRIHEAYVQAGADIIQTN
TYGANYIKLSRYGLEDETKQINEKAVRLARSAAGSAYVLGTLGGIRTFNKNAYSLDDIKR
SFREQLYLLLNEQPDGLLLETYYDLEEAREVLKIARKETELPIIVNVSMHEEGVLQDGTP
LSEGLKLLAGLGADVVGINCRLGPYHMITALEEVPLLEDAYLSVYPNSSLPSLVEGRLVY
ETDDEYFRNSAIEFRNQGARIIGGCCGTTPNHIRAMAEAVKDLPPVTEKQVKIRKKAAAA
VQNARTEPALNELAKEKRSIIVELDPPKQLNFEKFIRAAKELQSAGIDALTLADNSLATP
RISNVACGALLKQRLDMRSLIHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRIE
KKIACGADYFISQPVYSEEQLIKIREETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDAIREKMALAGDDKQKQAEEGLAIARSLLDAACDLFNGIYLITPFLRSDLTAELTAYIH
QKEKETTNVYHQ
>D6ZU56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum (strain JDM301)|TrEMBL
MHSPMFTLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPGLKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRAAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNAEPLFLGTQG
>A0A835RM82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vanilla planifolia|TrEMBL
MKVIEKIRDAVDGEGGRFSPLSFPPKDGGRVENLFDRMDRMVAHNPSFCDITWGAGGSTA
ELTLDIANRMQNMRLILMRFKMKEKLGLIEESKVTRSLPLRPPAKFSGPKKDVKPIFCAK
TARNEITLDRLRKM
>A0A8F6TQ06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sanguinis|TrEMBL
MTNTILTQAEAALAHDEPLFADVGGDIAVSFEFFPPKTEKMDAQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTMDAAAHLTCVEATREEIDQVAQAYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPDSVDKQADIDNLK
RKIDAGATRAITQFFFSPEAYFRFRDAAAAAGITAEIVPGILPVSNVAQTRKFAAMCGAC
IPDWMDRLFEGLDDHPAARQLVAATISAEMCRRLYAGGVKGFHFYTLNRAELAYAISHLL
GVRGKRAEAVAAA
>A0A482SVA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon|TrEMBL
MMPIQSYSSFQKMTTFCKTTVPPHIWTALSPVKDDDEATKQYGIQLCVDMCRALSSGGVR
GFHFYTLNLEKSVTSVLSELGVTADNSRRYAYVWVWVCV
>A0A1G5KMF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus polysaccharolyticus|TrEMBL
MKADLRTAMKQRVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTDI
FETNTYSANFDKLSKFGLESKVEDVNRAGVRIAKEVAGAEGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGVPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAIQFADLGARIIGGCCGTTPDHITAIKEALADYVPQPIAEPYPAE
ITSRIVLHENVDERAGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRALVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDPELIVAMREATKHLDIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVTIAKELLDVATEHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A1D9FRL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium formicaceticum|TrEMBL
MKIKEYFKEKELVKSFEIFPHNNKLPFKSIIKVVEELVQYNPAFISVTCGASGFEQTTQT
LDVASLVKNQFNTEVMVHLTSIAASEEKILNTLDTMKANDIENVLALRGDTPKDFEKEIE
RDFYYGADLVNFIVKNRKNEFSIAAACYPEGHFETVSEEQDIEHLKDKVEKGVDFLVTQL
FFDNNNYFNFHQKIKDKGIHIPISIGLMPAINTKLIRKIVGMCGAKIPQDLEKLLAKYEN
DEDSMFEAGIDYACKQIEGLVTYGIEGLHIYSLDRPEVVKAIYKNMNW
>A0A2P2E3T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira ryugenii|TrEMBL
MHISQVLTKRKTSISFEFFPPKNEEASEELFKNIQDLSSLNPAYVSVTYGAGGSTRDLTH
DLVLKLQEKTGLTIVSHLTCVGASKDDIHQVLKRYHSSGIHNIMALRGDPPKGESNFVKP
VDGFEYAGELVQFIKQHFPEMGIGVAGFPEGHPSTPNRLKEIENLKWKVDQGADYICTQL
FFDNNDFFDFMERCEIAGIKVPIIAGIMPITSRKGMARMAELSLGSRFPAKLLKSLSRAE
DDAYAENVGIHWATEQVRGLLDQNVAGIHMYTLNKSKATRKIYESLGIRNFDAI
>Q3UDB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mus musculus|TrEMBL
MNHQKAKVLPAGHCYPSLGMWASEAGCVRLSVPPSISRNPAMVNEARGSGSPNPRSEGSS
SGSESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRF
DRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCQQRPEEITG
HLHRAKQLGLKNIMALRGDPVGDHWEAEEGGFSYATDLVKHIRTEFADYFDICVAGYPRG
HPDAESFEDDLKHLKEKVSAGADFIITQLFFEASTFFSFVKACTEIGISCPILPGIFPIQ
GYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHF
YTLNREVATMEVLKQLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQD
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLS
GEPNRHGYRVTCLPWNDEPLAAETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPISFMFWKDEAFAPWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDSCLWQVVEDTFELLNRHPTERETQAP
>A0A559SM02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium mongolense USDA 1844|TrEMBL
MALNTGDRRNIGISFEFFPPKSEEMEGQLWKTVDELQDWDPDFVSVTYGAGGTTKAPTLT
AVTRFLNETPLATASHLTCVGATKGETHQVIDHFRKAGVKHFVALRGDAPGGAGVPYQPH
PGGYANAAELVAGLREIGDFEISVSAYPEKHPESRDVAADIDMLKRKADNGADRALTQFF
FDNDNFERYLEKVRTAGVKIPIVPGIMPIQNLTQLKRFASACGTVIPAFLDERFAGLDDK
VEERAKVAVDVAVEQIEDLVRRGLDEFHLYTMNRSSLVSAVLTNLGLRREGAKRAAGAAA
>S6AQJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas resinovorans NBRC 106553|TrEMBL
MSQERRYSFEFFPAKTEAGHEKLMTVARNLASYQPDFFSCTYGAGGSTRDRTLQTVLQLD
GEVKVPTAPHLSCVGDSKAELRALLAHYKDAGIQRIVALRGDLPSGMGMASGELRFANEL
VEFIRTETGDHFHIEVAAYPEVHPQARSYESDLANFVRKVKAGASSAITQYFFNADSYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDVQSIQAFG
EQVITEMCEELLQGGAPGLHFYTLNQAEPSLAIWKNLNLPR
>A0A1C3TXS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium hainanense|TrEMBL
MSHIDENPLGVHLPLDPLPGHYSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLNEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDAVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRTDALVAERLHQISEGREENQQAMAEIAA
HHTPQQAH
>A0A7Y5V3S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
PLGVRLEPYGPTSHDEARAAFAEQMAALKEGGADLFIIETFGDLEEIGQAVRAARDVDPL
MPVVAQMTIGTDGRTPFGASPADVAAWLDGLGAEIIGLNCSVGPQGILEGIEQMAPVTRR
KLSAQPNAGMPREVSGRAMYMASAEYMATWARHLVQAGARVVGGCCGTTPEHIHAIAEGI
RPLAPRLGSHRIGASREGAPAALRAEQAPAHDSRITIRDSAPLEPVPFPARSKWSAKLAA
KQFVTSVEIVPPRGVNADRMLADVALLRDAGVDAVNVPDGPRAQSRMGAIMTSLLIEQRV
GIETVTHYCCRDRNLLGMLSDLLGAAAVGLRNILLITGDPPKMGPYPDATAVFDIDSIGL
TNLVRNLNHGLDPGGNPIGEPTRFAIGVGCNPAAIDPALELRRFMYKVEAGAEFAVTQPV
FDVAQLERFLREIAGVRIPVIAGIWPLVSARNAEFLANEVPGVVVPAEILDRMRRANERS
REQAVAEGIAIAREMLALVRSAVDGVQVSAPFGKVDLALRVFADEP
>A0A6P4WNI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panthera pardus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEANSGRFSVPPSISISHLTLPLRVLAACPLTLLPSTP
CSRNPAMVNEPRGDGGPTSRSEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRMES
GDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIAST
AVNYCGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYA
ADLVRHIRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADT
FFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIR
NYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHP
KRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPRE
ELLKMWGEELTGEESVFEVFACYLSGEPNQNGYKAYLEFFTSRETVGALLQVLKKYELRV
NYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWG
KLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A7X8FYB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacteria bacterium|TrEMBL
MKIVDILKEKFTVSFEFFPPKNELGFKNFESNLKALKSLQPDFVSVTYGAGGSTRDKTKS
IIEKISLNEKINVMAHLTCILHNENELVNLLEYYKGINVKNILAMRGDVPFNRQGNFDIT
KEVFPHAINLMELIKTKYNENFSIGGAMFPEVHPESKNIEEDIFYLKKKIDCGMEFGITQ
LFYDNSLFYRYMDTLEKNNVNIPVLPGIMPITEYGQIEKFVNMFNASIPKKILEKFEKYK
ENPDDLEKFGIEYAITNCQSLIDNGVKGLHFYTLNKSKATILVYENIK
>A0A6P4XEM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panthera pardus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEANSGRFSVPPSISISHLTLPLRVLAACPLTLLPSTP
CSRNPAMVNEPRGDGGPTSRSEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRMES
GDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIAST
AVNYCGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYA
ADLVRHIRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADT
FFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIR
NYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHP
KRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPRE
ELLKMWGEELTGEESVFEVFACYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVN
RQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELR
VNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQW
GKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A7V9QKR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
MNTDRPDVREIANPERIMVVDGAMGTMLYSRGVFINQCYDELNVRSPELVLDVHRAYVKA
GAELLETNSFGANRLKLAQYGLESHVAEFNRRAAEIAREAAGVNVLVAGAVGPLGVRIEP
FGSTSREEARDHFREQMHALLEGGADCFLLETFSDLGEIEQALAAAREISLTTPVIAQMT
IGQDGLTPFGATPEDVARTLDDWGADVIGLNCSVGPQAILEAIERMAAVTKRKLSAQPNA
GMPRDVSGRTMYMASPEYMASYARHFIQAGAKLIGGCCGTTPEHIKALVDGIRPLIPRNQ
RKPSARYQMPHTHGLEDSGNESPAAALGVEEMPFALRSKWAAKIARHEFVTSVEIVPPRG
VDATSMLEGVSALKVAGVDAVNVPDGPRAQSRMGALMTSLLIEQRIGMETVTHYCCRDRN
LLGMLSDLLGASAMGLRNLLIITGDPPKMGPYPDATAVFDIDSIGLTNLVSRLNKGLDPG
GNSLGSKTAFTIGVGVNPAAIDPSYELRRFEWKVDAGAEYAITQPVFDVAQLERFLDSIA
HVRIPIVAGIWPLVSARNAEFLANEVPGVVVPEAVLARMRSASEKSKEHAVNEGIAIARE
MLQRVRDAVQGAQVSAPFGKVELAVRVFES
>A0A7K1Q741|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium vitis|TrEMBL
MAHTSSKRDQARPFKLSFEFFPPKSEEMEAQLWATVDELTGWEPEFVSVTYGAGGTTKAP
TLAAVRRLLAETPLATASHLTCVGATREEITQVVEDFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGFENAAALVKGLKELGDFEISVSAYPEKHPESADLAMDLDMLKRKVDNGATRALT
QFFFDNDIFERYLDKVRAAGINIPIVPGIMPILNLTQLKRFAGMCGTSVPAILDQRFEGL
DDKPFERTSVAAALAAEQIADLQGRGIDEFHIYTMNRAPLVNATLERLGLQRSDTVVSSP
AGVVA
>A0A1M5F4J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium segetis|TrEMBL
MKVTQHIEKAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGINN
VMALRGDAMKEEQSFVPKMGGNCHAIDLVQQIKLLNEGKYLHDVIHVDNKADFCIGVAGY
PEKHLESPSLLSDLKRLKEKVDAGADYVVTQMFFDNEKYFQFVAKAREMGITVPIIPGIK
PLAIQRHLQVLPQIFRIDLPEDLIQAVDNCKDNVAIKKVGIEWAIQQSRELKAAGVPVLH
YYSMGKSENIKQIANEIF
>A0A1D2S9Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp. SCN 65-56|TrEMBL
MGVPVSFEFFPPKTPEGVAKLRGVRQQLYALAPEFCSVTYGAGGSTQAGTFAAVQEILAE
GVPAASHFSCIGATREKVRAQLGELRAMGVRRLVALRGDLPSGYGMGGEFQYASDLVAFI
REETGAHFHIEVAAYPEMHPQARSPEADLKAFAAKVHAGADSAITQYFFNADAYFRFVNE
ARKTGLTVPVVPGIMPILGSTQLLRFSDACGAEVPRWLRLRLQGLGDDVASIRAFGLDVV
GRLCEQLVAGGAPALHFYTMNQSAATLELCQRLGAGPA
>A0A2N2HEQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-20|TrEMBL
MRIAQLLQRQEPFLSLEFFPPKDRAQWPGFFDVVRQLRDLGPLFCSVTYGAGGSTQHNTL
EIVARMKQEYGLEPLAHLTCVGADRARLGSFLAGLVQADVKNVLALRGDPPRGESTFTPD
SEEFQHGSDLVSFIRQDFSELSIGVAGYPEKHPEAASMDDDLERLRHK
>A0A1W6BV44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter cuniculorum DSM 23162 = LMG 24588|TrEMBL
MNSQTTFSFEIFPPRRDENISNLSQILEDLKALKPNFISVTFGAGGSVNSKHTLEIANLV
QNTHKIPSIVHLPCIHLSRERALEILKECKEKGLYSILALRGDVCEGAQKSRDFSYASDL
VTLIKKQGEFEIYAACYPEKHNESKNFVEDIENLKIKVDCGVDKLITQMFFNNEDFYKFK
EYCALKGISVPILAGIMPIINKKQILKISSLCGAKIPPKFMKILEKYEDNPRALEDAGIA
YAIDQIVDLIASGVSGIHLYTMNKSRAAKKIYEATSYLLKET
>A0A432I9T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacteria bacterium|TrEMBL
MKIKDLFKKKKTLISFEIFPPNKKFPVEKIYKVIDELADLKPDYISVTYGAGGTTQGRTV
EITKRIKNVNNIETMAHLTCIGATKESIDETLAQLKNNGVENILALRGDIPRDQKHDSYF
SYASDLVKHIKQSDDFSVAGAFYPEVHFENNDLLDLFNLKTKVEAGTDFLVSQLFFDNED
FYAFREKTKKININVPLVAGILPVTNYKQIQKIKELCNARIPRKFQVILEKFKDNPKALE
EAGIAFATEQIIDLIASGVEGIHIYTMNKSDVTRKILENIKHIRESIEEVE
>A0A1J4SZ63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG1_02_56_21|TrEMBL
MKVTERLKAGGKVFSLEFYPPKTEADSARLFEAARELKKLAPDFVSVTNSSSGTLPYRTV
ALSGVLKAELGLEVVAHLTCVAHTRSEISEICSRLKVLGIRNVLALRGDIHNLDGLSPRR
DYSYASQLTADLAATGDFSIGGACYPEKHPEAPTLDEDISRLKEKIAAGAQYLITQLFFD
NSFYFRFLEKTSAAGITVPILPGLMPITGYKQMQNFTEMMKVSVPAALRKGIERWGGDKD
GMFRFSVDYASEQGAGLLKGGAPGLHLYTLNRSRAAIAILKNVKGESE
>A0A3D3KRG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetia bacterium|TrEMBL
MIAGSNLERLLRAGKFVVTAELGPPNAADRTVVEKKXMTCRDRNRIGLQSDLLGAAALGM
KNLLCLTGDHPKFGDHPTAKPVFDLDSVQLLHMVKTMRDEKRLLSGTEIAVGPRFFLGAA
ENPFAGTIDIRARRLAKKMAAGAEFFQTQIVYNVEKFTAWMKAVRDMGLHKKAFILAGVA
PLKSPGMARYMKQNIPGMDVPDEIIARMKEKKSKEEGIQICLDIIEQLRDIEGVAGVHIM
AIEWEEIVPEIVEXPQNDPPKAD
>W8YH50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis DB27|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELIHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2B4NU02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS075960|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALMEEVYEATKHLEQPLFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8E2KVD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. 63-713|TrEMBL
MAISQIHPNWERAPDGITDGFSLEITAKDVDSLRAAAPAIPPETPIAVTFLPGEEAPARI
AAAKAVRALGFEPMPHFSARRITSEAEFQDYLDTVVQEAGVRRCFVIAGDPEHAAGPYND
SSELIATGLFEKAGIKAIGVGGHPEGHPNMSEEQCWEVLARKCVDIDARGMAPLVVTQFG
FDPDAALNWLVALRQRRIVAPVRIGVPGPAGIKTLMRFAARCGVGASASVLAKYGISITQ
LLGSAGPDKLVDALAKGLNESHGPVRLHFYPFGGLEKTVAWINGYRKSRA
>A0A0Q7JSC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Root444D2|TrEMBL
MKLDLRTALQRDILVGDGAMGTYLYQMGFPVGISYEELNLLRPETVADVHRRYFEAGARL
IETNTFSANREKLSKYGLEGDVEAINRAGVELARKAVGDEAYVVGAIGSIRAGKRKNVRT
TDVEESLREQIGILLDSPVDGLLLETFYDLEELQLALRIIRSMSDLPVICQFANEGTGST
QDGIPLQEAFQRLRDDGADVIGFNCRVGPNGILRSMEKLTPIAGIPFSAFPNAGLPDYVD
GHYTYAATPQYFAESALRFADLGARIIGGCCGTTPEHIAAVAKALHGYVPAAPGTMPSAR
AVRVSEPAPAKPAPPAGKPSLLEIVKQRKTVIVELDPPRDLDIEKFMQGSKALQDAHVDA
ITMADNSLAVTRMSNLALGYLVQERLSARPLIHIACRDRNMIGTQSHLMGLHALGIDHVL
AVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFVVGAAFNPNV
KHLDKAVQRLERKIEAGADYIMTQPVYDAKLIEQIYEATKHLNIPIFIGIAPLASGGNAE
YLHNEVPGIRLSDEVRERMSGLKGPEGRAMGVEIAKELLDAAMPFFNGIYLMTPFLAYEM
CVDLTKYVWEKSNRHDFHLYPLSK
>A0A6M1QVV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. KC13|TrEMBL
MVTGRGRSLAELINEGERSFSFEFFPPKDEAGEEQLWNAIRALEPYRPTFVSVTYGAGGS
TRDKTVAITGRIAAETDLLPVAHLTCVGHTRDEVAGILDAYAAQGVAHVMALRGDPAEGP
RAEWTPTPGGLDYAIDVVRLARERGDFRIGVAAFPEGHPGAESIEADADVLVAKAKAGAE
FAVTQMFFRAADYFGLVDRVRARGVDIPILPGIMPILNLAAIRRQSELIGAEVPDEIVER
VTAAGPDPADIRAEGIAVAAELCQELLDGGAPGLHFYTLNRSKATLEIFAKLNVTV
>A0A838PQA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
DNDHYFGFVEAARERGIDVPIIPGIIPVTNFKQLKRITGMCGASIPADFERELAEREDDA
DAVKDLGVSYATLQCADLLSRGAPGIHFYTLNKSPATRAILAALRAARPWDRALEPV
>A0A4R2D414|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella granuli|TrEMBL
MKPATASPARKDIRLSFEFFPPKSAEAEGQLWETAAALSAYEPGFMSVTYGAGGSTKAPT
LATVRHLLAMGLPAASHLTCVGATKEEVHAVVAEFQAVGVRHFVALRGDPPGGVGTAYRP
HPGGYANAAELTAGLRSLADFEISVSAYPEKHPQSPDVAADIDMLKRKVDAGATRALTQF
FFENDDFERYLERVRKAGIAIPVVPGILPVHNLSQVQKFAGLCGASVPGWLADRLAPVDD
RPQERAAVAIDLAARQVEDLIARGIGEFHFYTMNRATLVSAVCDRVGFARNDRHAAGAAA
>A0A7W0JZG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MRIAEILEHRRPVFSFEFFPPKTDEGQRTLGVTLGQLQDDRPDYVSMTYGAGGTTRNATV
ELTRWIKQDLGIEAMAHLSCVGEPTERLVEILGQIEAVGVENVLALRGDPPRGETEWTPH
PGGLDYSVELIRLIAERFDFCIGAACFPEIHPDAPDRESDLRYAREKQEAGAAFLITQLF
FDNELYFDFVEQARGAGITVPIVPGIMPITNYGQIKRFTEMCGASIPDELERELNGRADD
PEAVAELGVAYATLQCSDLLARGAPGIHFYTLNRSPATRSILAALRAAHPWTRAGATV
>A0A2K6DSP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macaca nemestrina|TrEMBL
MDHRKARVLPAGHYCPSLGIWASKAGSVRFSVPPSISRNLAMVNEARGNDSLNPCLEGSA
SSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDALELLNRPTQNEREMEAP
>A0A7X8LRI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MNVRELIDGHKAVFSFEFFPPKTEADTKALFNVIGELKTLQPDYVSVTHSATGAAPLKTA
ALARIIKENYGMEPIAHFTCIAHTRPEVRDIAKLLKEHGIRNVLALRGDRRPDAPPPPPN
PYNYAAELVRDLNAEGGFCIGVAGYPEKHPEAPSPEADIARLREKVDAGASFIITQLFFN
NADYFSFVDKCRAAGIAVPIVPGIMPVTSHKQLNRFSEMCGCVIPKHLAEDLERIKDMPE
AVVEYGIDFAYRQCKELLDKGAPGLHFYTLNRSVSTMAVLRRLKNEGYGK
>A0A7V7C6Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MYLKDLFARKKGATLSFEIFPPKKNMPMDTIFTTIEGLSNLKPDFISVTYGAGGSSKDRT
VEIASHIKQKHGIEALAHLTCISSTKEEIEGIVAKLQENQIENILALRGDLPQDPSFVFP
TPLHYRYASDLIYQLKQKKAFCIGAACYPEGHVECISLEKDIEYLKIKVNAGTDFLITQL
FYDNEMFYKFMDKIRKTGVNIPVLAGIMPMLSKKQIERCLSFSNTALPNKFTRLLEKYGD
NTELLTEAGIYYATEQIIDLLAWGVDGIHIYTMNRPEIARRITENITPFRRMLQK
>A0A2H5B8I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora sp. MMS16-BH015|TrEMBL
MSPDGKSLRALMQSSEPTYSFEFFPPKTAAGEAGLWQAIRRVEAVVPAFVSVTYGAGGSS
RERTIETVGRIVAETTLRPVAHLTAVGHSVGELRSFIRQLADGGISDVLALRGDPPGDPR
GPWTRHPEGFEHAADLVRLVKECGDFTVGVAAFPEKHPRSADWESEVRHFVAKCKAGADY
AITQMFFRAEDYLRLRDKVAAAGCDTPIIPEIMPATSAAQIARFAELSNATLPDELRSQL
EAAQGDPESGHRIGVEHATALAAELLAEGAPGLHFITLNKSPAALEIYRDLGLPRAAHLA
TDDRAAYTAAV
>A0A4P6WKV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter arsenatis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A197K2S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Linnemannia elongata AG-77|TrEMBL
MKIVDRIHQRQEEGRPFFSFEYFSPKTAQGMINLNDRIERMCHLSPEFVDITWGAGGSRP
AATLEVVSNVQKVLGVETCMHLICTDNPIKNIDKALKEARACGNQNILALRGDAPSGQKS
WTPCKDGLPSATALVRHIRATHGDYFGIGVAAYPELHPESPTLEHDLYYLKQKIDAGADF
IVTQLFFDVPKFLDWVREVRRYGVGIEVPIVPGLMPIQTYAGFKKNVVDAGLSVPQWILD
GLEAVKEDEVAVRQFGVEVGVKMVRELVESGLVAGVHFYTFNLEKSTRLILEGAGLVPFI
RKDKPWRTHFLPHRRRQEHQRPIFWANRPKSYISRTETWHQFPSTANQWQRSVNKYGSLE
GYGVGIKYPTAAEARLHWSNNDGRQPRRVGDLSEVFQRYWRGELQTLPWCDHPCGAGVES
GGEWESYRDRLVELNGVGCYLAINAQPVVNGVKSDDKVLGWGPSGGYVYQKAFLEFFVSP
DQLPILIDRLKTQYPTYTYNAINHSDDEEEEEEEEEEPNTVTWGVFPNHEIVQPTIVERS
SFLAWKDEAFALWDQWAQCFEGGETESDLTRKVLDEVRGTWYLMNIVNNDYHEPTGVFDL
FEEDFVRVKEVREADAKVVAVEASDVSQVLEAKEVTEVEEEVEKATRRQEEKDGSNVFSN
ALAAVVVAAAAAAGGRGVCQELVVVENIAVAEANCSA
>A0A536ZMJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTAEPPLDRRAASDLQARLRSGQFVITAEITPPVSTDPAEFLRRAMPLKGLATAVNVTDG
AGAKVHLSSLATAHFLVQSGIEPIFQMTCRDRNRLALQGDLLGALSLGIRNVLVLGGDDP
KAGDQPEAKAVYDVDSRGLLAMAHAMRSEKKLPSGTTIDGPPLHLVLGAADVPLDPPAGW
QPKALQAKIAAGADFVQTQFCMDIEVVRRYTARLEECGVKIPLLIGVAPIPSARSARWMR
EKLFGTIIPDAHIARLENAADPKREGRKICIEVLRSLAEIPGVAGAHVMAPMNFAEIPAV
IVESGVAGRKLAHAVH
>A0A377IZJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus pittmaniae|TrEMBL
MHPEAKSAQADLINLKRKIDAGANHVITQFFFDIENYLRFRDRCASIGIDTEIVPGILPV
TNFKQLQKMASFTNVKIPTWLAKAYEGLDDDQTTRNLVAASVAMDMVKVLSREGVHDFHF
YTLNRSELTYAICHTLGVRPNL
>A0A547NLF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM4303|TrEMBL
MIARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLDRILHDEITETQVDMVK
TAH
>A0A1M6S8G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas rosea|TrEMBL
MTGAMNEMSPPAPHQAKTLQSWLTGPRVGALPSLTAMPAPLLSFEFFPPRTEALEAQLWS
CVKRLEPLRPRFVSVTYGAGGTTQARTHATVTRILRETSLTPAAHLTCVGATREEVDEVA
RGYWEAGVRHIVALRGDPPAGQAGYEPHPGGYAYAADLVAGLKRIGDFEISVAAYPEVHP
TASSPETDLDNLKRKIDAGATRAITQYFFDAPTFLRFIDRAHAAGITVPIVPGILPVTNF
AQVAKFSAMCGAKVPDWMGKLFEGLDEDAETRRMVAAVVAAEQVRLLQANGVDEFHFYTL
NRPDLTYAIAHILGARPQG
>A0A0Q7IUW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Root444D2|TrEMBL
MTIYLGHGSSMRPDNFLVTAELIPPRNWNPRPLVEQAVRYRGYVDAVDLSDNLLAIARLS
PVVGAFFVRQVGVEPIVQINLRDRNRMGIQSDLLGLAALGVKNITILGGYPAKVGTEPNA
KEVYDLETMELVRYVRKMVDEGKLFDGTQMEEAPKFTIGTVENIAGKPIKELIDRLESKV
DKGTNFVRTQLVFDMDLIEEWMAEARRRGLHERASIMASVLPLRNADHVNTALKIPGIVI
PESFHARLAASDSKDEGIAIAAELITQLRRIEGIKGVHIRPIGGAEDSVNNLVKAAGLMP
ITPLSIGALGA
>A0A3D0LVV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTTRKPSFSFEFFPPKTPAGMEKLRTTRKQLAQLRPEFFSVTYGAGGTTRDRTLETVLEI
QAEGFEAAPHLSCIGATPDSLRELLDDYRQRGITRIVALRGDLPSGMVETGEFRYAADLV
AFIRREYGNQFRLEIAAYPETHPEARSARDGLINFKRKADAGADSAITQYFYNADAYFHF
VDECEALGVALPIIPGIMPIYNYTQLARFSDACGAEIPRWMRKKLEDYGDDDLPSIHAFG
LDVVTALCDKLLRHGAPGLHFYTLNQSAIVSTLWQRLGLR
>A0A5C8KEM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter sp. GY10130|TrEMBL
MKVTEHFNNAQKTLFTFEILPPLKGENMRTLFDHIDPLMEFKPPFIDVTYHREEYVYKQR
ENGLLEKITTRKRPGTVGICAAIQNYYKVDTVPHLICGGFSKEETENALIDLHFLGIDNV
LVLRGDCVKNESRFTPEPGGHAYATQLIEQVVDMNNGRYLDEEQTFKNHTDFCIGVAGYP
EKHSEAPNLKADLNWLKRKIELGADYIVTQMFFDTQKYIDFVKLCREEGINVPIIPGLKP
LTTKSQLSVLPSFFHLDIPCELAEAVEACRDNKQVAEVGVEWAIKQSKELMEFGVPCLHY
YSMGRSGSVRKVAEALF
>A0A1H7A1R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Demequina mangrovi|TrEMBL
METCPKRMEYGPCGGVGPHGECEAAPEPCVFLGAPVRRWAGIDGRTMPERGVRTAAAAAT
LARLDAGRVIVADMPALANGEDALRRCARILRDGVDVTLAGDAPDARVQLPPSLRAAIVQ
EEGLSLWAGVNARDRNRVALEGELAGLRVTGAGAVNCVTGDHPHTGHRPDAMPVFDLDAT
ELAALARAQGHAVAVAAAPSRGPVDARVPLLLEKERAGAEVCFVDHCGGSGPVGAFVAAA
RAAGSSLRFVPCVPVVTSRAGAALLASFPGFAAPPGYLEELGRATDARSAGIAAAVRLAE
QMLEVDGVAGVDLSGGAGPGEEEDYAEALAEIGSRLR
>A0A831RTT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiolapillus brandeum|TrEMBL
METSDKDTPAISFELFPPKTEKGMEKLKTVVGELNHLNPEYFSVTYGAGGSTQERTFATV
DWLREQGIDTAPHLSCIGTDKEEILEILT
>A0A7I7L0H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium cookii|TrEMBL
MLTDFSCLPFNRDDVAATAAVLAPGCDAVLVGEHQNRPDFPPTLMGSFLLDAGVVPWITL
SCRDRNRVVLEQELRGLRSVGVGTVLCVTGDGRGYDVRPEVTQTFDLDGPRLVALAASVG
VIPAVPETPTAPPVHARPARLVEKQRAGAGLAVLNHVPFPDTIAGFMATARSAGLAIPVI
AAVAVFTDEMSAAVLQGLPGLELDPAATEMVLHASDPVAAGIEAALVEARALLAIDGVDG
VNVSGLASAAGGRFGAEIKAEVGRRIREEVRRT
>A0A643CIR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balaenoptera physalus|TrEMBL
MDRPKPKVLPAGHCCPSLGMRAWXXXXXXXXXXXXXXXXXXXXXXXXXDPRAAGACFCAG
WGLSYAESGSSRGQSLERGSADSRNWRVEPPGGRVVTRTLTGLPPAWKCSISRLTLPCWG
SAACLPSHAPCLTPCSRSSAMVNEPRGHGGPSPRWEGSSSGSESSKDSSRCSTPVLDPER
HERLREKMKRRMESGDNWFSLEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDP
GSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITGHLHKAKRLGLKNILALRGDPI
GDQWEEEEGGFSYAVDLVKHIRSEFGDYFDVCVAGYPKGHPDSESFEADLKHLKEKVAAG
ADFIITQLFFEANTFFRFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIK
DVIEPIKDNDAAIRNYGIEQALSLCQELLASGLVPGLHFYTLNREMATTXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXGEASGPEFRPWSHRGESGGQGDQREVTECVRPSWQCWLPR
GHRDVCAVASGTLRAPVSAGMPSGLTFTSQDGKTQVQWCPLPLAKPRPFLSPFSPRRPLP
WAISAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYL
KSKSPKEELLKMWGEELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMK
EELLRVNRRGILTINSQPSINGKPSSDPVVGWGPXXXXXXXXXXXXXQGRTGLPPLDLPA
GVPRGWGQRPSSAQQRHPARTGGYVMAPVSLPQAYLEFFTSRETVEALLQVLKKYELRVN
YHIVDVK
>A0A833G415|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bauldia sp|TrEMBL
MQIACRDKNRIAIQGDVLGAAAMGVANILCLTGDGVQAGDQPGAKPVFDLDCMSLLETVR
TMRDAQKFLSGRKLTTPPSVFLGAAINPFAPPVDFRPLRLAKKIAAGAQFVQSQYCFDVA
MFRDYMARVRDLGLHEQCFILCGVGPLASAKTARWMRSNVPGVHIPDAVIARLEGAADQK
REGKRLCIDIIDEVKEIEGVAGIHVMAYRQEEYVAEIVHESGILKGRKPWRREPRADDAL
VAERLDHILHDAPLETPQEIVRDVAQ
>B2FSU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia (strain K279a)|TrEMBL
MSAPTSLRVQAFLDAFSLEVSARAMPALGAEATRIPRGTTISIPWLASEDDDARLAAARR
VRELGFEPMPHLSARRIGSRAVLERFLQRAANEAGVAQCLVIAGDLATPAGPFADSASII
ESGLLERAGIKVVAIGGHPDGHPVLGSDACWQVLEHKCQSIEARGMAPMIITQFAFDADI
VLAWLHALRARGIHVPVLVGVPGPASIARLVRYAAMCGVGASALMLSRYGISIGRLLGSA
GPEVFVDRLAGGLTDAHGLVSPHFFPFGGIAQSLDWINQHRALPSVARR
>A0A5F0FAE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMN-39-2|TrEMBL
MTATPTTPPADPDCRSSIPFSFELYPPKTDAATTALHATIDALAAARPKFISVTYGASGS
SRTSSLDVLRYIRRATIVDPMAHLTCVGSSHAEASSLIREFLDAGVSSFLALRGDPPEGL
TENDAFLGDLHSAGELVQLIHRVQAERVPYQETPIPGLPRARAVKTEREHVRIAVAAFPN
GHPRSRSTAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPV
TSPGRLRRILELSGEELPAELSIQLEVEPTLEGQREIGVSHAAALAEKLIAGGAPGLHLY
AFNQHETVLAVLDRAGALAPAQPVVSAHNPPPTHPSTSPADTRAGIHSTKDHY
>A0A1S9E0R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus oryzae|TrEMBL
MHIKEKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTYMPTEKVDAALQAAYKSGCTNILALRGDPPREKEKWEAAEGGLRYAKDLVKYIRDKY
GNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASFVITQMFYDTDLFISWVKKCRAK
GINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLETLEPVKNDDAAVKEIGKVLIADMC
RRLLAAGINHLHFYTMNLAQATQLVLDELKLLPSEETPIQRPLPWRPSLGLNRRAEDVRP
IFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDSYGIGLKGTNEQNIQLWGEPKSI
KDLSRLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLIELNNRGILTINSQPAVNGAKSSH
PVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNEDLTYHAVSKNGELRTNTHDSPN
ALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWAKCHAATSPSRKLIQGLVDSWYL
VNIVNNDFHNTYDLFELFKDLNVRDFDVEVAADNADLKSQENETAETTAN
>A0A1W9RRX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium 4484_87|TrEMBL
MKVIDHLIHGKKPQVSFEIIPPERGRSGKIILEIVEQLKYFDPTFIDVTSHSAVANYEEQ
RNGTIKRRVRRKRPGTIGICGVIQNRFGIDTVAHLLCRGFTQEETEDALIELEFLGIENV
FAIRGDDTNYHKPVDPHRHENVHANDLVRQIADLRSGKYVEEILNAEPMEFCVGVAGYPE
KHFEAPNLKIDVQNLKRKVDAGAGYVVTQMFFDNQKYFNFVNDCRKNEINVPIIPGLKVI
HRKNHIYSIPKKFFVDIPEELVDEMEANPEHASEIGFNWTLRQCRELLEAGENHLHFFVM
NDAVVISKLLKELLK
>A0A2G5K229|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amylibacter kogurei|TrEMBL
MSDPKFGLSFELFPPRSLEASFKMWSTLEGLVGLDPSFVSVTYGAGGTTRDLSKSAVGVI
ADHYGLNVAGHLTCVGATRTETLQVAQDYAAAGAKQIVALRGDAPNGATNFEAHPDGFSG
SIELIEALAAQNQFNIRVAAYPHVHPDSANADHDIVMLHSKFKAGADSAITQFFFEAEDF
LRFRDRAEKAGIKNKIVPGILPVENWAKTKVFSQRCGAQTPDWLDKAFSNTKSKAEHDLL
STAVCTELCDDLINEGVEDLHFYTLNDARLTSDVCRALGRSVTPPVAAKVA
>A0A561Q2H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga polysaccharea|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPAFINVTYHRSEHMFKKK
ADGSFEKVEIRKRPGTVGICAAIMNHYTVDAVPHLICGGFSREETENALIDLNFLGIDNV
LVLRGDAPKNETFFEPDPHGHSYAIELLDQVAHMNNGVYLEDDLQGGVKTNFCIGVAGYP
EKHFEAPNMQTDLAHLKRKVENGADYIVTQMFFDNQKFFDFVTKCREMGITVPIIPGLKP
LTSRKQMTMLPRIFHVDIPADLSTEILKCKTDKDVELVGTEWLIAQSKELKAFGVPVLHY
YTLGKPKVIQKAVAAIM
>A0A7Y0EPY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium sp. DSM 109957|TrEMBL
MTAPLFSLEVFPPKRNAPVGTIYDTLDGLEGLKPAFISVTYGTGKLKDRTATARIANTIR
AEYHIPAVAHLTAQYLDKEAVDEALDMFAAAKVEGVLALRGDKVEGQEPAGVFDHASDLV
SYIRATRPEFKVYGACYPEGHPQAPSFQADIDNLKRKVDAGATHLISQLFYDNEDFYRFL
DAARAAGIDVPIEAGIMPVTNEKSVRRMAAMCSSRVPESLERILNKWGYDSYALTDAGIN
YASAQISELLAHGVNGIHLYSMNKPAVTRRIWRNVEVLFRS
>A0A8J6UHB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelovirga terrestris|TrEMBL
MTEISLELVPRSESSLRKELELVRRHLPLVQRINIPDILRFDMRSWQGCAIAGEYVSRTI
PHLRAIDFNPDAPLPIIDQLCQENVEAVLIINGDPPQEMKHTYYRTSSLEMIRRLKRECP
KLTIYAGIDPYRSGIKAEIDYLRAKQDAGADGFFTQPFFDLRLMEIFQGFLRNTTIYWGV
SPVLTESSRSYWENKNHAIFPRDFAPTLEWNREFARKVLEFAHHHDDNVYFMPIKTDIIK
YLHGII
>A0A1A9W1W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glossina brevipalpis|TrEMBL
MSSNISNTTHLGAHFLPDVHTTTKLESAKCSYEPKFRFREQPQLCKYPKTQHLKIAIAEK
IEKKEYFYGIEILARSYNSKLVLDYTKFGKMLPLFTSIVWLGLDYSRITNVEKVGSVRVA
KKLKDKQHEMLIAPHLSCYGLDTKRLNEFIKLNFTNIVIVRGDQYDNEQEFKYASQLVAQ
IKRECQDSITIAVAGHPEGHPSISTMQEDMKFLVEKISVGADLIITQVCFNAQSLIDFIK
TCRLNSINIPIILGIFVPDNIKSLLFLMELTKIEMLPEDLEQYRYYAEKGKDEFRFFAAQ
KVTQMILTVLEAENVNIYGIHFFTMNKFGMVTKVLEELRKYIKI
>A0A1Q9NJZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Heimdallarchaeota archaeon LC_3|TrEMBL
MKIHEYIKDHQGEPFISFELIPPKRGARYRDIEERIEILSRFNPPFIDVTTHASEIIYQE
SKSGIKKLFKKKRPGTHGICAIIQHKFGIEAVPHILCRGFTREETEDLCIDLHYLGINNV
LAVQGDERGYEPPYVNGGHNRYANELVSQINNLKEGIYLDEDSLNEETFDFCIGVGAYPE
KHYEAPNMEYDLQFLKQKIDAGACYMVTQMFYDNQAFKSFVKQASDFGINAPIIPGLKVF
TSKKQLNSLPKIFHINIPPELTKRTMKANDSNILDIGIKWAVEQCKDLLEFGVPGIHFYV
LENASVVAKVIDQLKDKKLI
>K9PGW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix sp. PCC 7507|TrEMBL
MPDIKSTTVLNNFRQAAQAGEFLVTAEVAPPKGGDPAHMIKMAATLKGRVHAVNITDGSR
AVLRMSSLVASVILLQNDIEPICQIACRDRNRIGIQADLMGAHALGIRNILALTGDPVKA
GDHPDAKAVFDLEAVRLLQLIRKMNQGVDHNEQLLTDGALDLFTGAAVDPQCASWSGLQS
RFERKIEAGAQFFQSQLITDFDRLEKFMDNIASVHKKPILAGIFLLKSAKNAQFINKVVP
GVNIPQHIIDRLAKAKEPLAEGVKIAAEQVQIAQQLCQGVHMMAVKREDLIPQILDLAGM
GKVTH
>A0A8J3G119|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algimonas arctica|TrEMBL
MTRSVPQRDPNAPVGAIARTSSDRSVTKNSSDVCVSFEFFPPKTVKAETRLWTAIETLEP
LGPDFVSVTYGAGGSTRERTHRTVERMAKETRMNPAAHLTCVEATRDEIDIIAKDYWAAG
VRHIVALRGDPTSGIGDKYQPHPDGYAYASDLVEGLKRIADFEVTVSAYPELHPESGDWR
SEIDNLKRKIDAGATRAITQFFFSPDIFWRFQDRVLDAGIDIPIVPGLMLQPNVKGLQKM
SELCGVAVPDWYVELFEGLDNEPTTRDMLTATLISELAAELHDRGVRHYHLYTLNRAEIA
NAVSRVLGLHRRQSIGDQSVGPSLRA
>A0A014BV10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_7|TrEMBL
MKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGKARDIQDFEQFLEQA
QTANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGGVRIGGAFNPFKYVE
AERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKAFLTKNNYSQQILACVMPLTLGRA
NFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKHLGFAGIHLSACHKP
EEQMLLESYIEQYRHLELNVLEELWNSLWQVTTGKEFSPEIVRFSRQPTSKQLIKYRQLH
VMHEAMFGSKIAKGVGRFIFKASFWENALIAKLLLKTEVLSKHSLVGCESCGQCRLGDTL
YICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVEQTEILKDKLIPTVSIE
TRGTSSWKNWYLGAEA
>A0A543EWK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia bhagyanarayanae|TrEMBL
MRGRSTPGRPSPTPPIVSGTPSVVQSLQVHSGRMVPFSVEFNPPRDAAGEARLWRAVREF
ERMHPAFVSMTYGAGGSTKDRTVRVTGELAQETTLLPVAHLTAVGHSVAELRSLVGAYAD
SGIRNILVLRGDPPGDPLGEWHKHPEGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPD
LETDTAFLAAKLRAGAEYSITQMFFEVDHYLRLRDRVVAMDPVEGAKPIIPELMPITSLR
TVTRAEELCGRALPDSVLERLREAAGDGPEEDRAAVREVGIEIATEMAQRLIDEGAPCLH
FITLNFAKATSEVLTNLGYGVTAAPVSA
>A0A2V6CKS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIADIMREDSPTFSFEFFPARTPDAAEILYHTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHDEEEIEAILLRYAKSAIGNILALGGDRPRGIEYDKSR
DSFQHAIDLVKFIRRFNEAGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVGAGA
DYIVTQLFFDNRDFYDFRERCALADIHIPIIAGVMPITSMSGFKRIAELAAGARFPARLL
RALQRCENDPEMVRRVGVHFALEQCHDLLDNNVAGIHFYTL
>A0A1I6HQ67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoreibacter janthinus|TrEMBL
MTRPNVSFEFFPPKSVEASFRLWDTIQTLAPLDPTFVSVTYGAGGTTRELTHEAVTALHK
TTDLRVAAHLTCVDATREETLAIARDYMKAGVTDIVALRGDAPKGQSFAASEDGFASSIE
LIEALKTETDATIRVGAYPDSHPEAGSMEANIAYLKRKFDAGADAAITQFFFEADTFFRF
RDACVKAGIDKPILPGIFPIEDWTRASNFAKRCGTAVPAWLDEAFTIAIRDDRHDLLAQS
VVTELCSDLVDGGVADLHFYTLNRPELTRDICAALGVTPKLALAQVA
>A0A2V6EBM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIADIMREDSPTFSFEFFPPKTPAAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
HLVERIQHTTKLDPIPHVTCVCHNEKEIEDILVRYAKSAIGNILALGGDRPHDIPYDKSR
DSFQHAIDLVKFIRRFNESGAHPDPRGFGVGVAGFPEGHPATPNRLIEMDHFKAKVDAGA
DYIVTQLFFDNRDFFDFRERCALADIHVPIIAGIMPVTSMSGFRRIAELAGGARFPAKLL
RALRRCENDPESVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRVIFDSLGIPRRR
NAQAPTV
>A0A1B9H971|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kwoniella heveanensis CBS 569|TrEMBL
MTQLTSLISSHDGPFHTFEFFPPRTEAGLVNLLDRIGRLAAAPMPAPLAVSVTWGAGGST
ADKSLELAEQVVKLGVEVILHLTCTNMAKEKVDQALEKCRSLGITNILALRGDPPRSEEY
AVDPNPQPDFFQHADDLVRYIRKEYGDYFCIGVAGYPTPHSDSESAESDLHYLKVKCDAG
ADYIITQLFYDVEGFLEWVTTCRERGITQPIIPGIMPIQNFSSFRRLVNLTKCPVPESIM
ADLQPISSDDAAVKRYGAELATRMVRQVFQSGLVPGVHFCTLNLEKSVRTILENLGWSAT
SDPNLRASPFIRYNRLIEDDEPQTNGAIAINGHSDGSPKNQVKDLSISPSEASVLAQWGL
THHAPPPVPKRGLGTQGGPGGITGASGEDSWDEYPNGRFTDVRSPAYGEIDGWGSGLKIT
AAQALKEWGTPTNVNELAKFFVSYLESSPSTPTTPFCDLPLSSESIPILPHLIALNSEKI
QHWTVGSQPAVDAANSEDPVFGWGPRGGYVFQKAFVEFFVREEEVKRLEEKVEKKGNGLI
SMYAGNKKGDFRTNTEKDAVNAVTWGVFPGQEIVQSTIIEAESFHAWKEEAFDIWTEWSL
LYPRLSPSRRLLESIAGEWWLVSLIHHDYKDPDALWKFLLEE
>A0A3D1U962|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MKIRNLIDDGKPEISFEIFPPKKDAPAAPVKEAVRRLAELKPSFISVTYGAGGGANVNTA
DVASFVQ
>A0A432FCV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MRFIRDIHAGKEAAGKPTISFEFFPFKTPEGEETFFGKTLPALMTAGPDYASVTYGAGGS
TREKTLEIVERIQNDFGLTTMAHLTCIRHTRAEIGGILDEAANRGIQNILALRGDAPPGE
NWAQTEGGFEFASELVTHLRERGGFGIGVAGFPEGHIDCTEGRDADWRHLVGKINHGADL
VITQMFFDNADYFRLADYLKGQDVAAPLFPGIIPVASAAQIKKFSAMCGATLPEKFASRL
DELGDDAEAVREYGIEYATGQCRELLERGAPGLHFYTLNKSKSVLRILDNLGMA
>K7ZYK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter condimenti 1330|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATADELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPALELKT
A
>A0A2V5UTY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRSSPPTFSFEFFPPKTPEAAEVLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
ELVERIQHTTKLEPIPHLTCVCHNAEEIEAILLRYAGSAIGNILALGGDTPAGIAYDKSR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPVTPNRLLEMDYFKAKVDAGA
DYIVTQLFFDNRDFLDFRERCVLNGIHIPIIAGVMPITSIRGFKRMAELAGGARFPARLL
RALQDCQSDPEMVRHIGIQYAVEQCHDLLDNDVAGIHFYTLNRSDATQVIFDSLGIPRHR
DVQASSV
>A0A1F2FHK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC11E11|TrEMBL
MSEFPPPAVGRQVPIRHALTLPSPGPIPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFA
SVTYGAGGSSRDRTLRIAERVSREPLTTLVHLTLVGHSVPELRQILRAYLERGLTNLLVL
RGDPPGDPLGDWTPTPDGLQYASELIELIRDEEEFADFEIGIASFPEGHFRAPDLESDTR
YTLAKLRAGAEYSITQMFFDVDHYLRLRDRLVAADPEHGAKPIIPGLMPITSMRSVRRQL
ELSGSALPPALDERLTRAAAGDEEANRDEIRKVGIEVTTEMAERLISEGVPGIHFMTLNF
ARATQEVLHNLGMAPAWGTGQDMVRGGF
>A0A356I7L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
LHYCCRDRNLIGMQSDLLGGYAGGLRNYLIVTGDPPKLGDYPDSTAVFDVDAVGLTQVVN
NLNHGIDVGGNQINPPTGLLIGVGANPCAVDPEREINHYLNKINAGAEYAITQPIFDAEA
LLRFLDSVEKKGDSIPVVAGVWPLISYRNAQFLKNEVPGVEVPDALLERMSHAKTKEDGR
ALGIEIAREIRDVITDRVAGFQVSAPFGIVDLALQVLE
>A0A2V5Y2E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
HPATPNRLLEMDHFKAKVDAGADYIVTQLFFDNRDFLDFRERCALADINIPIVAGIMPIT
SISGFKRIAELAGGARFPARLLRALQRCQDDAEMVRRVGLHFAIEQCHDLLDNDVAGIHF
YTLNRSDATRMIFDSLGIPRRKPEISTV
>V4T4S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrus clementina|TrEMBL
MKVIDKIQEKVASDKVVFSFEFFPPKTEDGVENLFERMDRMVAHNPAFCDITWGAGGSTA
DLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDK
FVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLK
KKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTVHLYTLNMEKSALAILLNL
GLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRTVGWDQYPRGRWGDSRNP
SYGALSDHQFMRPRSRDKKLHEEWAVPLKSVEDIYEKFKNYCLGKLRSSPWSELDGLQPE
TKIINEQLGKINVKGFLTINSQPAVNGERSDSSSVGWGGPGGYVYQKAYLEFFCSPEKLT
ALVDKSKVLPFITFMAVNKEGNWKANVNQTDVNAVTWGVFPAKEIIQPTVVDPASFKVWK
DEAFEIWSRSWASLYPEGDSSRKLLEEVGSLY
>A0A1M7EAE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira sp. Nsp11|TrEMBL
MESQKKFAPTFSFEFFPPQTPEGVEKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETV
LEIQTEGYVAAPHLSCIGATSENIRDMLQKYRAGGIRHVVALRGDLPSGMAQGGEFRYAN
ELVAFIREEFDDTFHIDVASYPEYHPQCNSAQEDLQNFKRKVEAGADSVITQYFYNADAY
FSFIDACEAMGISVPIVPGIMPINKFSQLARFSDACGAEIPRWIRKKLEGYGDDSASIRA
FGLDIVTDLCDRLLNAGAPGLHFYTLNSAGPTTTIWQRLGL
>A0A179D4D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosulfurimonas dismutans|TrEMBL
MRSFRRNLYEKDFLVTFELVPGRSTRTRHYRDIIGFAEKVAEDGLFDALSITDNAGGHPA
LAPEALGRELKRMGHEPIIHFSCKDKNRNKIESDLLALDREGLHNLLILTGDYPRYGYRG
RAKPVFDLDSVSLLRLISEMEKGFLLPPEVPGGGITLPPIPFFAGCVVNPFKWSEAETVT
QYYKLIRKLRAGARFVITQVGFSARKFQELKFFLEEEGFGEVPILGSILVMDVRLARILY
RGAVPGITVTERLLKTVEAEARRPDKGREAALLRAAKLMALLKGLGFQGAHICGAPLDPV
AARELLAMAEEFYPSWKEFLPEFSEAPERSFFLYDRDPETGLNLRRRRGLSPRSVRSLTF
LFSGLIHRLFFSSKAPFFRLTKSFFERLSGSRFEKYFARLEYGFKKPLFDCQECGDCTLG
ELAFLCPQSQCAKYLLNGPCGGSRDGWCEVYPGKRRCVYVRIYERLSPEERRKKLLENEI
PPRNWALYRTSSWLNFYLGKDHHSLLTHRKS
>A0A3D1U953|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
RICQLSGSFLPARFKAIVDRFGDDPASMTEAGIAYATEQIIDLFANGVNGVHVYTMNKPD
IAERIMGNLKCILGR
>A0A1H8Z6B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. yr375|TrEMBL
MSETPVSETRTTAPPGLIDGPLEGLLDGFSLEMTGKDVPGLEQARATIPPGTRINVTFLG
NEEPQARLAAARAVRRSGFVPVPHISARRLRSRAELAEFLGALRAVDAVEDIFVVGGDPA
VPHGPYDDAAAVLRSGLLQEYGVRHVGVSGYPEGHPAIADGVLWSALEDKVRLLREQGLR
GSVITQFGFDAGPVLTWVEALRERGVDLPVRVGVPGPAGVRRLLTYATRFGVGTSAGIAK
KYGFSLTNLMGTAGPDRFLHTLAERHDPARHGELGVHFYTFGGLAATSDWVAARRHGDDG
DPGNHGGHGSA
>A0A434WZ00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.010.02.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLRGRQPWKREIRRDDQMVADRLDSILHDDITETQVDMVK
TAH
>A0A7H1Q6I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseofuscus|TrEMBL
MLAGGKTTYSFEFSAPKTPKGERNLWTALRRVEAVAPDFVSVTYGAGGSTRAGTVRETQQ
IVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGAWVAHPKGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVVEAGCDTPVIPEILPVTSVRMLERLPKLSNAQFPDALKERILAAKDDPAAV
RSIGIDFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLGLHHPPQA
>A0A6I4U7C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteriqipengyuania halimionae|TrEMBL
MISLKQMDDARTALDAPLFSGLAGDIDVSFEFFPPKTDKMAETLWHSVGTLKPLKPRFAS
VTYGAGGSTRERTHDQVVRIQNEAGIPAAAHLTCVDATREEVDAVARHYWESGIRHIVAL
RGDPSDGSTTYTPHPGGYANAVELIGGLKQVGDFEISVAAYPEIHPDSADRDADLANLKA
KFDAGATRAITQFFFDPQCFFEFRDRAAAAGIEDEIVPGIMPVMSFAAVERMSGLCGTAI
PDWMEGLFEGLDDRPEARQLVSATIAAELCRRLYAGGARQFHFYTLNRAELSYAICHMLG
MRPKDADHG
>A0A5E4HKN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon|TrEMBL
MSFISKLRSGKFIITAEISPPKGTDTSRMLRDAVLLKGIADAVNVTDNQRAVMRMSPLAA
CSILQKKGFETIMHITCRDRNRLALQSELIGASALGIRNVLVMSGDHPSKGDHEGAKPVY
DLDSVQLLGMIQELNRGVDISGNKLDGKTDFFMGAVTNTELNEAGLIKLKKKIKMGASFL
QTQAVFDVKKFSEFIEKKSEIELKQSKQIKIIAGIIPLRSERSALFLNKVPGIRVPDDMI
KQIKDAKNPEAEGMRITSDIIKELRTLCDGVHIMPVGNHEHTKKLLEMAGLI
>A0A2M4BU60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles marajoara|TrEMBL
EEPAVSSLREKLTQIFRPTSGEGEPSAVRSVFYSIEIAAKDDFNIDQLRRLTPPPVFCSM
PWISAENLRYAADFAQMPSLRLADQLRREQITVVNHLSCYNLTEVQVDKLLSTQPSIRNL
FIVRGDTVSPDQQFQHSAQLLQHLRQYESTRTTTAATPKLTIGVGGYPGGHAESPSQEDE
LRHLADKVALGADFLLTQTLYDAASFFRYRDRCRAVGITIPIIPGIYLPHSYRQLQTMLN
ITRVAMTPTVRALFEEHRNDTPEAFEAFVVQYFVELVRELLQSNAIEPGSSSDPVGLVHF
FTFNKFSLLEKVISQLKFGQQ
>A0A6L9FHI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. V39_P1S14PM300|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDASREELIQIADDYWANGIENIVALRGD
IPAGGGRPEMYASDLVQLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVECYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPGWMARQFD
GLDDDPTTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPR
>A0A8F5F103|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp. NLF-1-9|TrEMBL
MALPLSLEFFPPKTPEGASRLRAARQQLYALAPEFCSVTYGAGGSTQAGTFATVQEILAE
GVAAASHFSCIGATRAGVRAQLAQLKAMGVKRLVALRGDLPSGYGMGGEFQYASDLVAFI
RAETGRDFRIEVAAYPEMHPQARSPEADLKAFAAKVQAGADSAITQYFFNADAYFRFVDE
VRAAGLELPVVPGIMPILGATQLLRFSDACGAEVPRWLRLRLQGFGDDVASIRAFGLDVV
ARLCERLVAGGAPALHFYTMNQGAPTLELCRRLGLGQA
>A0A3S3R9G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.039.01.1.1|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A1G1QG57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium RIFOXYB2_FULL_45_11|TrEMBL
MTFKEKIQAGKFILTSEVGPPKGIESGRILEDVELVRGRVDAINVTDLQSSVMRLGSLAV
SIRLKEKGFEPVYQVTCRDRNRLALQSDILSAANFGIENILALTGDHPKLGDHPHAKAVF
DIDSVQLIQVIRRLEQGLDMAGKKLEGVLPKFCVGAVVNPGSDPLEPQIMKMEKKIDAGA
EFFQTQAVYDLKSFENFLSKTKHLKTTVIAGIVLLKSAGMAKYMNENVAGISVPDNLINE
MRDTKDKQAQSIEIAARLIKELKPMCQGIHIMPIGWDKLVPKVLDAAGL
>A0A1T1PA30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis pv. melhusii|TrEMBL
MIPTDMPSGASTITDTYSLEVSVKDIGALTNAAPRILPGSDMFIPYLPGQTEAARLAAAQ
RVRRLGFEPVPHLSARRIGSLEELQAAIARLVGEADVTRCLVIAGDPSTPKGPFADSVSL
IETGVFERSGIRTIGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
IVMTWLEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISVGKLFGN
AGPDRFVDRLVSRLTEAHGDVRLHLFPFGGIAQSVEWVAHYRSCEASQDRVSSVAAD
>A0A437RLJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquincola rivuli|TrEMBL
MSTEHKPVPISFEFFPPNTPVGSDKLKTVVQDLSAVKPEFFSVTYGAGGATREKTLATVK
DIAAMGHEAAPHLSCVGSTRESIREILGTYRAQGIRRLVALRGDLPSGTAVAGEFRYAAD
LIAFIRQEQGADWHIEAAAYPEYHPQQRYAKKDLEHFAAKMKAGADSAITQFFFNPDAYF
HFVDEVRKLGVTAPIVPGIMPIHNYAKIAQFAARDGIEIPRWVALKMEGYLDDAASVRAF
GIEVVARLCRRLIDGGAPGIHFYTLNQSALSLDICKQLG
>A0A426SES0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseofuscus|TrEMBL
MALGTASTRTDRARTVRDMLAGGKTTYSFEFSAPKTPKGERNLWTALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVAHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVEAGCDTPVIPEILPVTSVRMLERLPKLSNAQF
PDALKERILAAKDDPAAVRSIGIDFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHHPPQA
>A0A0Q5XGR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Leaf383|TrEMBL
MSTRTLYPAERGDLRLSFEYFPPKSDEMDAQLTRTAAALNAYAPEFVSVTYGAGGSTKAR
SLTTVRRLIDDCAIPSTAAHLTCVGATRSEVDAVVDEFAAAGVRHFVALRGDPQGGIGAQ
YQPFPGGYENAAALVEALARRGRFQISVSAYPEKHPESSDVDADIDMLKRKVDNGATRAL
TQFFFDNNDFERYLERVRKAGISIPVVPGILPINLFSQVSKFAGLCGARIPEALALRLAH
LDESPEERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLIMAVCDLVGFKRTDEIAEG
AAA
>A0A0W1GHA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. H071|TrEMBL
MTSNLNSLAEARRAAASPLFANLDGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLAPSFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASRAEIDEVARAYWEAGVRHIVA
LRGDVPGGEPYRAHPDGYANAIELVAGLKAVAPFDISVAAYPEVHPDASCAEADLDNLKR
KLDAGATRAITQFFFSPEAFLRFRDAAAAAGIAAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMVSLFDGLDDHPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVANAKDQAA
>A0A7G8E972|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. A15-44|TrEMBL
MSTALQRAIEAGDQVLTAEVMPPRGADSSHMLAMAASLQGRVHAVNVTDGSRAVMRMSSL
ASCKLLLDAGLEPVLQMACRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAGDQADARP
VNEFESVKLLQQVDALNRGVDPVQGTLPDGATTLFAGCAADPQSRSWSGLQRRLQRKQAA
GARFVQTQMVMDPEALERFQHELAGPLGLPVLAGVFLLKSAKNARFINRVVPGACIPDAL
IHRLECAENPAMEGVAIAAEQVKRYLGIVHGVHLMAIKAEERIPLILDRAGLSSLPG
>D5BST0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceispirillum marinum (strain IMCC1322)|TrEMBL
MSATIEQIQAAASDWSIEVTPNGASKIDSFADCLAPGTTVNVTFLPGSDPMDTVAVAQRL
HNDGMNPVPHLAARSLKDTDQLDALLSAFTQKAGVSEVLVIGGGVDSPVGQFASSIEVLN
TGLIQKYGITDIGVAGHPEGSPDISDEEIVEALMLKNELAKRDGLNLYIETQFCFEADIV
LAWEKSIRDAGNNLPIRVGIPGPATIKTLFRFAQVSGIGPSMRFIAKQAKNVAKLMTVQS
PHILLDDLAEGMAADKDCMIKHFHFYPFGGFAKTAAYAQAIADGQIKSLPKGGFEALVA
>A0A660YS74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MGKSFREHLEQDEVLVCDGAMGTMLYSKGIYINRCFDELNLSNPVMVKDVHLDYLKSGAD
IIETNTFGANWFKLEPHGLEGRLYEINFQGVKIAREAAGDKAFVAGSIGPLGRPIEPIGH
LSQEEARQAFYDQAKAQFEGGVDLFILETFKDINEIHQALLAVKDVCDLPVIAQMAFTDE
GKTAYGVSPEEVVRKLEGWGADVVGINCSTGPEGVWKAIQEMARVSDIPLSAQPNAGFPQ
LVQGRLLYLASPEYFAEYAKRFIQSGVRIVGGCCGTTPAHIRAIRTAVKALRPSRQLVEV
KVVEVEEKVLQVKKPAEKSKLGEKLGKKFVVSIEMNPPRGPDFSKVVEGARRIKVAGVDA
VNIPDGPRASARMSPLALATILESKVGIETILHYTCRDRNILGMQSDLLGAHALGLRNIL
IVTGDPPKLGDYPTATAVFDVDSIGLVRIANNLNNGTDLAGNPIGAATSFHIGVGANPGA
ISFEEEISRLKQKIEAGAEYILTQPVFDIKLLEKLLDGIKEYKIPVLAGILPLVSYRNAE
FLHNEVPGMSIPKTVRDRMQRADSGEEAKKVGVQIAQEVLQEVKNMVQGVYLMPPFGRYE
VALEVVEVLK
>A0A8C3QT14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanoderma ruficeps|TrEMBL
MVNETQQTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLASGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGYKVSCMPWNDDPLATETNLLKDELEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLNSATQQ
>A0A414B7G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum hallii|TrEMBL
MRMNIREYLENHKLLTDGAMGTYFDSIEKENYICSEEANITNPALVREIHRSYVKNGAQL
LRSNTFLANEGTFLSLTQAKAEAFENITLKQLIIAGYQLAKETAQEVYQEEYPIFAAADI
GPILEERDSEEADILQQYYEICDSFLEAGADIFVLETFPDTQYVLKMAEYIRKSCPEAFI
IGQFSLTPTGYSRTGFHYKTILQEATQSGLLDGAGLNCGVGAAHMKKFLKSYIEEFGVPE
DMVLTSLPNCGYPQIVRGHAVYSDSVPYFGEKLGEISELGVQVLGGCCGTTPEYIGEIYK
TVFQAKKTEGAVKIPTKIVWGDVTKRVQKRKEAAVHITQAGEQKEAIKEKQVTNTFRQKL
EMGELVCAVELDPPFDTEDTKLLNGAKALLSTKADIITIADSPLARSRADASLMAAKIKM
TTGMDVMPHLSCRDKNRIAIRSGLLGSYASGIRNYLFVTGDPVAREDREFTKSVFDFNSI
RLMKFAQSMNQEVFKDDTIFYGGALNQNGASPENIAGRMLKKMEAGCRYFLTQPVYDKEG
IERLTFLKERTGAKILIGIMPLVSRRNALFIKNEMPGIHVPDEVVAKYKEGASREEFEEA
AIEISKQIIEMGKGIGAGFYFMTPFNRVSLVKSILEYV
>A0A2E2E874|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSHRIRIGFEVFPPKSGSSETFESSVATLAAVGDYVSVTYGASGSGRERSETAINALVAQ
GHANKIAAHLTASSQSKDQIDRLARDWKAKGIRRIVALRGDAPAVTGDEYPCAAALTEAL
SQIGGFNIAVACYPEGHPKSASKAAEMDHLKRKFDAGAREAITQFFFNIEDYLRFRDDCR
AAGIHQPIIPGLLPIASLEGLHRFAAGCGAKVPGWLDARFAGLEDDPDTVRTLSVATTVS
LSDRLIAEGVDHIHLYTLNRVRDALTIARALGITGTDTAVITQKEEAA
>A0A3D3VB94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MMASQADKPSVSFEFFPPKTLEMEKALWDALCDLAPLEPAFVSVTYGAGGTTRERTHATV
SRIVKETGLTVAAHLTCVDATREEIETVARGYWSEGVRHIVALRGDPPTGQTKYVPHTDG
YAYAADLVAALRAVAPFELSVAAYPETHPEAVSSDLDIDNLKRKVDAGAVRAITQFFFDN
DLFFRFRDRVVAAGVKIPLVPGIMPVGNFKNMMRFADTCGAGVPDLMAAAYEGLDDDPAA
RAEVGKRLASEQCLDLCSNGVNDFHFYTLNRSELTGAVCANLGVTGGGPEIDLK
>A0A5S5AWA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosediminibacter litoriperuensis|TrEMBL
MGLREKLESGGFALTAEMAPPKGVNTSRFRECARGVKGRVDAVNVTDFQSAVVRISSLGA
AIMLLEEGIEPVMQLTGRDRNRIAIQGELLAAGALGIKNILALTGDHPVFGDNRQAKPVF
ELDSVNILQIATLLMEGKDLAGNPLDGAPDFYLGASVTPLFNPLELQVLKMEKKIAAGAK
FFQTQAVYDIEVLRRFREKTAHLDAKVLVGVIPLKSPGMANYMNKNVPGIFVPEGVIERL
RNSENKVQEGLRIAAEFIMQAKEEKLCDGVHIMAIGAEENVPILLDMCGF
>A0A4P7AD16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum huttiense|TrEMBL
MSTHNFSIEFFPPKTAEGTEKLRATRARLAALAPKYFSVTFGAGGSTQQGTRDTVLEIIG
EGHNAAPHLSCIGSSRASLRAILEDYRAQGIKRLVALRGDLPSGYGAMDQASSEFRHANE
LVEFVRAETGDWFHIEVAAYPEMHPQARSPQDDVQNFARKVKAGANSAITQYFYNADAYF
RFVDEAARLGATVPVIAGIMPITNYTQLMRFSDMCGTEIPRWIRLKLASYGDDTESIRAF
GQDVVTQLCQRLLAGGAPGLHFYSLNQAGPTEAIWQQLVK
>D5P9P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium parascrofulaceum ATCC BAA-614|TrEMBL
MSAGPECPKRMEFGPCGGVRPDGQCEMRPGACAFDDVVAWSGHQPAPWRVRAPLVLTDFS
CTPFDRDDLAATAAVLAPGCDAVLVGEHQNKPDFPPTLLGSLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSIDVETVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASTGVVAAVP
ETPTAPPVHARPARLVEKQRAGASLAVLNHVPFPGMVADFITTARAAGLTIPVIAAVAAF
TDSVSAAVLQGLPGLELDQAVTERVLSAPDPVDAGIAAAVDEARALLSIDGVEGVNVSGL
ASASGPRIGAEIKAEIGRRIREGRR
>A0A2D7TU52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MTSISFEFFPPKSAEAEEKLWRAIGRLEPLAPEFVSVTYGAGGSTRDRTHACVRRLVDET
RLRPAAHLTCVAAXRAEVNSVVEAYAEAGVRHIVALRGDMPDMGGFAPHDDGYAGSVELV
QAISARGGFDITVSAYPEKHPESRSFADDIDLLKAKVDAGATRAITQFVFDTPAHLRFRD
AVAAAGVSIPIIPGIMPTTNFAGARRMAEACGTSVPDWLSAAYEGLEDDLDTRKHIAASV
ATDQCRMLIDEGFEYLHFYTLNQADLTFAVCRILGLGGGGQESDAI
>A0A2G3B0J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum chinense|TrEMBL
MKVIEKIQEAIKNDKVIFSFEFFPPKTEDGVENLFERMERMVTHGPSFCDITWGAGGSTA
DLTLEIVKRMQNMVCVESMMHLTCTNMPVEKIDQALDTIKSDGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGIATKEIYENDLAYLK
KKVDAGADLIITQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTK
IPEEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILANGIKQLHLYTLNMEKSALAILMNL
GLIEETKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDEYPHGRWSNAQNP
SYGALTDYQFMRARSRDKKLQEEWAVALNSVEDIYERFKDYCLGKLRSCPWSELEGLQPE
TKIINEKLGHVNTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSQEKLN
ALVEKCKSFPYLTYMAVNKEGNWISNVNRTDVNAVTWGVFPAKEIIQPTVVDPASFMVWK
DEAFEIWSRGWAQLYPEADPSRKVLQQVQNSYFLVSLVDNDYINGDLFSIFKDI
>A2BUC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus (strain MIT 9515)|TrEMBL
MKSKLQQTLEKNSKVITAELMPPRGGDPIRSLKIAQLLKNKVHAVNITDGSRAIMRMCSL
AMSKLLLENGIEPIMQISCRDRNKIALQSDILGANALGIKNILCITGDSVKAGDQQETKA
VHEFEAVRLLKQIQYFNQGIDPTFEKLADNRTNIFAGAAVDPSCRNQRSLKNRTRKKKEA
GANFLQTQIVMDRNYLIDFCQEISNPLEIPVIAGVFLLKSYKNALFINKFVPGANIPENI
LNRLKEAKDPLKEGILIAAEQAKDFINIAEGIHIMAVKAENLIPEILEKAGLNLEC
>A0A660CCV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella rugosa|TrEMBL
MSPQPSAPHRDALAGALRNASYEVLPFRSTEDKVLAHVPPTVPLTVTATEAKGLEATVEL
AVRLGKNGYQAAPHLPARLVRDRAELDDIAARLLESGIERIFVIGGDAAEPAGDFPDAES
LLIALAEAGHSFRNVGIAGYPEGHGRLPDTVIDDALRAKAGRAHEIITQLCFDPATTIGW
ARRLHAEGLRTPIRVGVPGSINRQKLIRVSASLGLGQSARFLRKQSAMFWRFFLPRGYRP
DTLIAGLAEQIGSSDNALAGIHVFTFNDLANTERWRQRWLARLT
>A0A3C0Q6V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSTRPTLSFEFFPPKTPAAAEILMASATDLQRLTPDFVTVTCGAGGSTKAGTFEAAKRLK
DELGYTVGAHISYFGTPKVDLLEYAETLWEDGIRHLVALRGDIPDGVNAGDYNHDDYFQF
TSDFVEALLATRPFDVSVGAYPEKHPDAPDMAADIRALKLKCGAGSKRAITQFFFGTDIY
TGFLEQVQEAGIETPIVPGLLPIADFARAKMFAVKCGASIPSAIEERFLQSSDPQQTAID
LLASQIDDLTNLNVSHLHFYTLNRADLILSAFQKLGKI
>A0A8C1UHG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
GPVLSRGTACPGRSSKSDSSGVSNSGESSKESSRCSTPVQDADRTDRLRDKMKRRIESGD
HWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATD
LVKHIRCECDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGAHFIVTQLFFRAETFL
KFVKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSY
GIQQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEAL
LQMWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNCR
GVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVN
YHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQEEGSPS
>A0A7X6Y9L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MTFFEKLQSGRPTVSFEFFPPKTPEGWARLYATLAETARLDVDFVSVTYGAGGSTRENTV
DLVASLQNNLALHAMAHLTCLGHSQVDLSKILDRLAAKNVPAIMALRGDPPQGESSFRPH
PYGFSHASDLIGFIRDGWPHFKIGCAAYPEGHPESFAEGQPHTPARDIAFLKRKQENGAD
FAVTQLFFDNAVYHDFVAQARAAGVTIPLLPGIMPLSSARQIERFVALSGCSIPDTLRQA
AASADVEEAGFRFALAQCRDLLTRGAPGIHLYTLNQSSLSGRILAALRAEIPGL
>A0A841IW59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium subterraneum|TrEMBL
MNTDPISSLPPVTHALGQTPLYADLGGDAQVSFEFFPPKTEKMEQQLWASISALAPMGPR
FVSVTYGAGGSTRERTHATVERIARETDIPAAAHLTCVGASKAEIAEVADAYWQAGVRHI
VALRGDPPVQGKAFMPHPEGYASAADLVTGLRALHPFEISVAAYPESHPEAVSAQSDIEN
LKRKIDAGATRAITQFFFSADTFFRFRDAAAAAGIDAEIVPGILPVSNVAQTRQFAAMCG
AEIPAWMDRLFDGLDDHPGARQLVAATIAAEMCRNLYTGGVRNFHFYTLNRAELSFAICH
LLGLRAKGVSS
>A0A1H9SZQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gracilibacillus ureilyticus|TrEMBL
MKSLQKELQEKILIADGAIGTLLYAHGVDQCFESYNVSKPEEVLQVHRSYIEAGADIIQT
NTYGANYIKLSRFGLEEQVHQINVKAVQIAKQAARNNTFVLGTIGGIRGVQKLITSKKEI
TRSFKEQLFTLLLEGVDGILLETYYDLEELRTVLEIVRKETELPVITNVSMHEPGILENG
TPLTDAFYQLEELGADVVGINCRLGPHHMIESLESVPLLDKAYLSAFPNASLPAYENGRL
VYSEQTDYFKQCAIKFRNQGVRLIGGCCGTTPEHIKALKEGINGLDPVTRKEIKEENPLI
ITRDEPQQEDHNPTILDTVKERQTVIVELDAPKHLEIDEFIEGVKQLEKAGVDAITLADN
SLATPRISNFAMAMKMKELNLNVKPLIHLTCRDRNLIGLQAHLMGLHTLDFHDILAITGD
PTRIGGFPGASSVFDVTSFELIRLIKQCNQGLSFSGASLRRKTNFQVAAAFNPNVANLEK
AVKRMEKKIEHGADYFLTQPIFNHEQIIALYRETKHLNTPIFIGIMPLVSHKNAEFLHHE
VPGMKLSDEVRARMQAHSNRNDAIQEGIQIAKELIDTAINYFNGIYLITPFMHYQITTKL
TKYIIKVNNERKILH
>A0A8C2C9W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
GPVLSRGTACPGRSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGD
HWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATD
LVKHIRCECDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGAHFIVTQLFFRAETFL
KFVKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSY
GIQQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEAL
LQMWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNCR
GVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVN
YHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQEEGSQS
>A0A2S4T3C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ABNIH27|TrEMBL
MSHVSPCFQQNQFFVLMEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEVSKS
YPESIDKVLHFSGKARDIQDFERFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVK
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEAMFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKKTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A6S6QM26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrihabitans soli|TrEMBL
MTPAPTERLSRNGAARDISVSFEFFPPKTEESEKSLWECITRLLPLAPQFVSVTYGAGGS
TRERTHQTVTRIVRESDVPPAAHLTCVAASKAEVDEVAQSYWDAGVRHIVALRGDPAGGV
GSKYEPHPDGYAYSADLVAGLKKIGNFEISVAGYPEKHPESRSLDEDIDILKAKVDAGAD
RVITQFFFENDIFLRYVDRVRKAGIDIPIVPGIVPVHSFKAVSNFAARAGASVPDWLAQR
FDGLENDPATRQLVASAVAAEQVLDLRDRGVTHFHFYTMNRADLVYAICHLLGLRVPAAA
>A0A1F9C0V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_49_23|TrEMBL
MTFKERLESGKFVVVAELQPPKGIDLSELYENAERLKGRLDAVNVPDLQNAIMRLGSLSV
CALLKEKGLEVIANLSCSDRNRLALQSELLNVSALGLKNVLILRGDPPSIGDHFEAQAVF
DLDVMGLLGAAKRLQEGYDLMGNDLQGKPQLFVGTQVNAAAKGHVLDLEMMDMEKKIRLG
ANFFFTGSIYDPGLLENFVKKVAHFKVPIIAGITLLKSVGMARYVNKHVEGALIPDSVID
RLMKASDKQKASVEIAGDLIRAMKPLCRGIQIIPIGWENLIPALLDQVGL
>A0A351Z459|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophus sp.|TrEMBL
MKSGSNLEKVFTNGHFAVTAELGPPKNNDVSVIQRKVDFLRGYIDAVNITDNQTAIVRMS
SIATSVFVIQMGMEPVMQMVTRDRNRIAMQSDLFGATALGIKNIVCLTGDHHTFGNQVNA
KNVHDLDSVQLINMVKTMRDEKTLMGGEEKIEGEVNLFIGGAANPFADPFEFRALRTAKK
AAAGVDFIQTQCIYDMVRFKEWMKMIRDLGVDKKVHIMAGITPLKSAGMARYMAKNVAGI
TIPDALIDRMAKAAKGSEEGIKICVEQIQEVREIEGVHGVHIMAIEWEQMISKITEMAGL
LPRPKVD
>A0A435A3W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.011.01.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDITETQVDMVK
TAH
>A0A1V3KG58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter heylii|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMENLLWESIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDASSEELKKIAQDYWDSGIRRIVALRGDEP
KGYDKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHIIT
QFFFDIDSYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPSWLTKAYDGL
DDDPTTRNLVAASVAMDMVKILSSEGVSDFHFYTLNRSELTYAICHMLGVRPSV
>A0A4Z1D428|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces bauhiniae|TrEMBL
MAGALLDGASLEMTGKDVPRLAEARAALDGGTRINVTYLAGEDAGMRLAAARAVREHGFV
PVPHLSARRLPSSAELERFLAGLAEAGAVENVFVVGGDPARPEGPYEDALSVISGGLLQR
YGVRHVGICGYPEGHPAIGDDALWSALTGKAAALQEAGLAGDVITQFGFDADAVLTWLEA
LRGRGVHLPVRVGVPGPAGVRRLLGYATRFGVGTGATVARKYGLSLTNLMGTAGPDRFLD
DLADGYDPARHGTVKLHFYTFGGLRPTAEWITRYRRERG
>A0A101CVW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium CRH|TrEMBL
MKVTEHIENAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
VMALRGDAMKDEQYFMPKAGGNDYAIDLVKQISLLNQGKYLHEVMDADNRANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFKFVEKAREMGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIHAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASHLF
>A0A2D6ZRQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacteraceae bacterium|TrEMBL
MSKDNIVSLLNGFTVELNPKVRHKLNSIPLDKKNNVYITYLPDATEKDILETVEFVSNQN
LVPITHLPARTMKDLEHVSSFLKELRKRTDSKKILVIGGGGNQNGSISSSLEILESDLLN
DNDFTEIGVAGHPEGSPDINQETINDFLNKKYDLSQNKNLNIELVTQFFFNASPFIDWCQ
DLKAKNINLPVRVGFPGPASFKTLLNFGIMSGVGNSINFLKKNSSKVTDLLTKTSNDDML
IELANFAQGENSLKSFHCFPFGGFEKTCLWLNAVQSGEFTIDNSKIVLHKKIF
>A0A2M7TB04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aquicultor secundus|TrEMBL
MGFKEEIQSGTFVVTAEVGPPKGTDLSEMKHHIEGLKDKVTALNVTDNQSAVMRVCTLAI
AQVMMDMGLEPIYQMTCRDRNRLGLQSDLLGASVLGIKNVLSLTGDHPVLGDHKDAKPVF
DIESVGLLEVISGLNEGHDMAGLELQGKTDFFAGAIVTPEANPLEPQLAKFEKKVKAGAK
FFQTQAVYDMPKFMKFMDYAKQFDVPIMAGILLLKSAGMAKYLNKFVAGVSVPQELIDEL
APYKGEDALKKGIEIAGRQIAELKSICAGVHVMAIGAEDKVPDILAAAGL
>A0A5C3NKB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polyporus arcularius HHB13444|TrEMBL
MKITQKIDQAAKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
DLTSELVKTCQKLIGIETCMHLTCTGMPKEKVDIALREAKQHGCRNVLALRGDPPVGKEW
EAVEGGFQYGVDLVRHIRKHYGDYFDIAVAGYPQTHRLPPEEAAREMQYLKDKVDAGANF
IFTQMFYDIDMFVEWVRAARAAGITIPIVPGIMPIQTWNGFQKATSLAKITVPRTFLDEL
EPHKNNDEKVRELGTKLVANMCRQILAADIGIRGLHFYTMNLEKGCRMLLEELNLVPRVE
VVKPLPWRQSLTPNRRTETIRPIFWANRTRSYLSRTENWDEYPNGRFGDSRSPAYGELDG
YGVWLKQSKEDALKLWDTPTTIADIHALFAKFCIGQLQALPWSDTAPSSETTVIAQQLAK
LNE
>D5ETP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23)|TrEMBL
MSVTEFIHQDKEAKRFSFEVLPPLKGTGTAKLFADIDKLREFDPAYINITTHHSEFVYHE
LENGQFERRRIRRRPGTIAIAAAIQQRYQIPVQPHVICSGATIEDIEYELLDLQFLGIND
LLLLRGDKAKEDSRFQPTPGGHAHTTDLMAQVKRFNEGFFADGTPIKNPGRPFDYGVACY
PEKHEEAPNLEMDMQYLKQKQDLGAQYAVTQLFFDNEKYYAFVEKARQMGITIPIIPGIK
PMAKLSQLTVVPKTFHCDIPEPLAKEVVKCKTDEDAKQLGIEWTTQQCKDLYAHGVHNIH
FYTVSAVDSVAEIVKRLVVRG
>A0A1M7YCZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila aestuarii DSM 18488|TrEMBL
MSLNEKLGNDFVITTELGPVKGVLVDESLEKASAYLPLSGINVHDCPMANLRINAVAMGS
LIQNKLGIDAIPHFTCRDRSLLGTQADLLAAHALGIRNILVTTGDLPKHGPYPSKAVYDY
NTFELIRLIGKMNSGLDYNEKEFGGKTDFTIACTAMPTAKNLDLELGRMTEKISAGADFF
QTQVVYDAEKAIAFLKEARRFGKPILTGVMPLKSVKMARFMNDNVEGIDVPEEVIARMEH
DGANGIEITCEFIEKIADYTDGIHIMAMGDVKGTNRIIEFINGLVAR
>A0A1E4U086|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pachysolen tannophilus NRRL Y-2460|TrEMBL
MKITEKLNKAHDVSNAPPATFSFEFFVPKTSQGVQNLYSRMDRMYQLNPQFIDITWNAGG
VLSNLTTEMVNTSQSVLGLETCMHLTCTNMSLEVIDNALKSAYDSGCQNILALRGDPPID
GSESTGTFKYSKDLIKYIKTKYGDHFNIGVAAYPEGHAEEGDADKLIDFLKEKQDCGGDF
IVTQMFYNADIFIEWCKKIRAKGITLPIIPGIMPIATYASFMRRAKWCEINVPENFLKEL
ELIKDDDAKVRLKGCELVSNMCLKLLKSGYVNHLHFYTMNLEKSTIMVLEYLNLIQPNLD
INSNKLTPWRKSLNPTRSNETVRPIFWANRKFSYIERTNNWDEFPNGRWGDSRSPAFGEV
DLFHNGLIRHSAKKTLELWGRPTKEEQLSDIFIKYLKGEIKSLPWSDDPISPETNPIVNE
LIDIIKKGYYSINSQPCINGLPSSDKINGWGPKNGYVYQKMYLEFLCPASKAPELLRKID
SINSEFQTGNCLTYYAVNSRGELSTNSKEDDINAVTWGVFPGSEVLQPTIVEKISFLAWK
DEVFKIINEWQGLYNSDSKEDAEVRELLSKLHDEFYLVNIVDNRYADGKSNDRIFGLFD
>A0A7C7QBT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MRNSFKSGSNLEKILRAGHFAVTAELGPPQGADPEVIRRKARLLKGVADAVNITDNQTAI
VRMSSIASAVLALQEGLEPVVQMTCRDRNRLAIQADLLGAYALGARNLLCLTGDHQSFGN
HPTAKNVHDLDSMQLIRVVKDLRDEGRFQCGDEIKGVVPRFFIGAAANPFADPFEFRPYR
LAKKVAAGVDFIQTQIVLDIPRFREFMKRVVDMGLHEKVYILAGIGPLKSAGAARYMRDK
VPGMMVRGEYVERMAAAVHGIPKEDKKARREAWRQEGIRIAIEQIQEIREIEGVAGVHIM
AIEWEEAVRPIVEGAGLLPRPQM
>A0A7W0J8T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTDKVTLIERLKTGKPILSDGAMGTMLHSRGITYEGCFDCLNLSHPGLVADLHREYIEAG
AQIIQTNTFGANRFKLGRHGLADNLVKINAAGVDLARRAVQASFKEILIAGDVGPLGVPL
APFGRVQVDEARAAFEEQISALSAAGVDLIIIETMTDLHEIVEAVKASKSVAPKLPVVAS
MTFTRDNRTLLGDSPAKVAKRLHEAGADVIGINCSGGPNQLLNILKQMKSALPEGLFSVM
PNAGWPEQVEGRIMYSAGPDYFGEYAVSFWQAGACVIGGCCGTTPAHIKAMAEKITATTA
VEVISKRETEKSQTDNESQEVFPPTQMAQKLRDGKFFIAVEMDPPRGLSTGKLIAGASLL
SQAGADVIDVADSPMARMRMSPWAVCSLVQRKVGIETVLHFPTRGRNLLRVQGDLLAAHA
LEVRNIFVVMGDPTSIGDYPGANDNYDLVPSGLIKLIKQGFNSGHDHAGTEIGQPTNFFV
GCALNLNPVDMESELKNLRRKLKAGADFILTQPIYNPELVTKFYEAYEREDGKLPIPLIA
GLLPLASARHAAFLQQEVPGIDIPEEVHQQMAESGAQGAKAGIRLTVELVEQIKTKVQGV
YLMPAFSRFDHAAEIIEQIRGNS
>A0A521SUM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MKMSQFLELLESSPNPILFDGAMGTQLHVRGASFQSCFDSLNLSNPALVAEIHHDFIMVG
AQVIMTNTFGANRFKLADHGLAAVVTEINRAGVELARKAATASFKEVLVAGDVGPLGVRL
APFGRVQLEQAREAFAEQIQALADAGADLIIIETITDLYEAREAIFAAHDVCNLPVVASM
TFTRDDRTLLGDAPAKVARELHRAGADVIGVNCSGGPAQILRIIKEMKEAVPEAHLSVMP
NAGWPEQVAGRIMYPAGPDYFGDYALAFRHAGVSIIGGCCGTTPEHIRAMHTALESMPDS
EYKNGLSIRMVEPAKAELSDDTPSQLAQKLAAGVFVAAVEMSPPRGLSTHKMQAGAGLLA
DAGADVINVADSPMARMRMSPWAVSQLIQHNIGIETTLHFPTRGRNLLRVQGDLLAAHAI
GIRNVFVVMGDPTHIGDYPEAMDNYDLVPTGLLKLIKQGFNMGLDHSGTEIGQPTSFFAG
AALNLTSREADREIKVLRRKLASGADFFLTQPVFDPAEAKAFLDQYAAEYGPLDKPVLAG
ILPLYNARHAAFLDNEVPGIDIPQEYLDRMEAAGEDAPKEGVRIALELIEAIRPFAQGVY
LMPQFGRYEIAAEIVEAVKAKVAD
>A0A7C5Q569|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTNKFLTRLEQGPLLNDGAMGTMLYARAPGFKQCFDELNISNPAVVAGIHRDYINAGAEM
IETNTFGANRIKLAEYGLEQQVAAINTAGVELARRVVEASFKDVLIAGSVGPLGARLAPL
GRISPEAAFDAFQEQITALLSAGVDLLIFETFSDLLELEQAVAAARALDAAAPIVAQITF
ANDGLTPLGDSPEKVAKKMAEWQVDVVGVNCSVGPARVFKTISKLKRLLPAETRLSAQPN
AGWPQKLGGRMMYPATPDYFAEYAVSFARAGVSLIGGCCGTTPAHIAQMRQALDNPPPEA
LIVHPPRASEEPAYTTDTLAPTLLAQKLAAGDFISSVELHPPRGASASKVLAVGQMLQEA
GVTVVNVADSPVARMRMSPWAVCHLLQSEAGLETVLNFPTRGRNLLRIQGDLLAAHALNI
RNLFVVMGDPTTIGDYPEAFNHHDVVSSGLIHLVKHKFNRGLDYADRQISQPTNFLVGCA
LNLNAPSPEREINLLKKKIDNGADFAMTQPIYEAAVFDRFTALYEERYGAL
>A0A7V9G5T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRLDQLFATRNQTLSFEFFPPKNERAWYTLEDTIDQLVPLGPDFISVTYGAGGGTRAKTR
EVVEHIQAKTGVTAMAHLTCVNATKDELRALFDEYHGAGIENLLALRGDPPKGEARFTPT
DGGCAYATDLIDLIRTDRRFAIVCAAFPEGHPDNPSRSADWDWLVEKFRRGATAAITQCF
FEARPYQELVEHVTRTTGKRQRIIPGILPITDFHALERFCARCGATIPDSVRATLAPLAD
DPIAVRKAGIACTVAFCQDLLEAGAPGLHIYALNRSTAAAELVTALRLAGCLN
>A0A7W0GP07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrinomonadaceae bacterium|TrEMBL
DELNLSNPDLVREIHAEYLHAGADIIETNTFGATAYRLHQYGLKGSLVDINVAAVRIARE
AAGDHAHVAGAIGPLGLRIEPYGPTSFDEAKDMFKAQGSALLEGGVDLFLLETFSDVSEI
RQAIRAIRELCDLPIIAQMTIMTDGNTTFGTTPEVFTARLDEWGADVIGLNCGVGPAIIL
SGLEKMRAVTKKKLAAQPNAGLPRDVQGRQFYMCSPEYMSKFAKRLIQSGAKFIGGCCGT
TPAHIKLISDAVRAASPRAQRMVMSSGPLALVEEIVPADIKVVPAEERSNWSRKIVRGEF
VTSVEVLPPKGVDAQKTLDSIRLLKDAGVDGVNIPDGARAQSRMSAMATAVLVEQQIGIE
SVLHYCCRDRNLLGMMSDLLGASALGLRNLLLITGDPPKMGPYPDATAVFDIDAIGLTNM
VNKLNHGLDIGNNPIGQPTAFCIGVGVNPGAINPEEEIRRFEYKVEAGAQYAITQPVFDT
DQLRDFIKSVEHVRIPIIAGIWPLVSYRNAEFLHNEVPGVRVTPSIMERMRAASAISKEA
GRDEGLKIARESLLEVRDLIQGVQVSAPFGNVKYALEVFGALEEFSRKEAEVATNRSAEE
>A0A7W0FF54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPGFTPARRWQQAYYPFKNRTVGQKIEEALERTIKGALFGCRMCGNCLLQETALICPMEC
PKGLRNGPCGGSTPDHCYVDETRPCVWYKIYERAEKYGRLDVLMEVLPPLDWDKVGTSPQ
PDGWNNLRKHGGIKAISRYLRSTPEIRKQKWEHFFKEIRQPDWWQGDSLPHPAPLHVPVS
HLEQILSDGNFAITAEIAPPLSASPDDLVKKILMLKECVDAVNFTDNPSSTPRMSSLACS
LIALQNGVEPVLQIAARDRTRMGLQGEVLGARALGIRNILCLTGDHPRLGPGPNGRMDIW
DIDAIQAMWIIRRMRDEAQFLDCREIKCAPQVFIGAAGSPYASTPLIQAMREEKKVNAGA
QFMQTNLIYDFDGFQQYLEALDRREVTRRVPILAGISPIRSIKAAYAMRQVPGVKIPDWL
IHRMEASADPKEESVQITLELIDKVKALPGVRGIHFMAVGWESIVPRLIKDSGLR
>A0A399ZTK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MINKFLDLLENQTLLADGAMGTMLHARGVGFDKCFDELNLTNPSAVAEIHREYIEAGAQL
IITNTFGANRFKLTKHGLQEDVREINSKGVELAKRVIAASFKEVLVAGDVGPLGVRIAPF
GRVQPEEAREAFAEQIQALSEAGADLIAIETFSDLYEIREAIKAAKEVERLRESPLPVVA
SVTFTRDDRTLLGDEPMKVARTLREAGADVLGVNCSGGPAQLLRILKQMKQAAPESKFWV
KPNAGWPEQVGGRIMYPADADYFGDYALSFREAGACVVGGCCGTTPQHIAVMKKALESST
YTSTLVLTSEIFETSEVSETEPPTQFAQKLGRSEFAISVEMDPPRGLSTHKLLAGASLLA
DAGADVINVADSPMARMRMSAWAVCDVVQRKVGVESTLHFPTRGRNLLRVQGDLLAAHAL
GIRNIFVVMGDPTSIGDYPEAMDNYDLVPSGLIKLIKQGFNEGVDHSGTSIGQPTNFFVG
AALNLCPPDVDNEIKNLHRKIKAGADFFLTQPIYRADDGPKLLEAYETKHGKMDKPILVG
ILPLVSVKHASFLHNEVPGISIPEETRKRVEAAGDEGVKAGVEIAVELVEQVKPWAGGVY
VMPQFHKYDMVAEIIEAVKVKT
>A0A3M1RAU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
PEQRERIVVHLTCKALNRNALEAYAWRLAAEGIRNILALTGDYPTAGFGGAPQPVFDLDS
VGLIYLLSAMNRGLEVPGRGGKKQTLPPTDFYIGCAVSPFKRTERELVPQYFKLVRKIAA
GARWVITQLGYDMRKFHEVKLFLEARGIRDVPVVGNVYVLTKGVARLFHQGKLPGCVVSD
ELWELCNKYGSGPDKGREFFRELAAKQLAVFKGLGFQAGYLGGLAKPEDFFDIIERAERF
GENDWRDFLREIRFSLPDEFFFFEHDPETGLSSSDRINPVYLESKKRPARSREVTWSYRL
SRWVHRIAFTRNKGLWNLLKRLYARWDKKPGLAAKAMYSLEKTSKFFMYGCRDCGDCSLP
DCAYLCPKRWCSKCARNGPCGGSHDGICELDDKPCFWARVYERLKAYGEEEEMLTGEPVL
YNAQLMYTSAWANTYLDRDHHAPKDDSADTEGKSSPPNGG
>A0A800G5D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRIVDLYGQGRPIFSFEFFPPKTDAGENKLMETMADLKSAVEPDFVSVTYGAGGSTRDRT
HGVVTRIQDELGITGMAHQTCVAASRTDVLENVKRLVASGVENVLALRGDPPDTDEDWQP
PADGFSHANELLEFLTAEFDLSLGAACYPEVHPEATSGDDDLAWTREKVKSGAGFLTTQL
FFQSDCYVQFVARAREVGIAVPIVPGIMPITNLGQIERFTKMCGAELPAELRTRLQRCGD
DAAAVMATGIEHAITQCRELLEAGAPGLHFYTLNKSHATRSILAAMRQL
>A0A7X7RK67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oligosphaeraceae bacterium|TrEMBL
PDGPRAAPRLSALATALLIQNQVGMEAVLHVCCRDRNYIGLQADLLGCAALGLHNLLFIT
GDPPKLGNYSFASGVFDTDSIGLVKLQKHLNQGVDLGGQSIKPPTAAVIGVGADPSAIDF
QREIDRLHQKAAAGAEYITTQPVFDIAALQRFLEAVADLHLPVIAGIWPLVSLRNALFMK
NEVPGVQVPDSVVARIEAAESAEEQLAAGIAIAREAVQAVRGLVAGVQVSAPLGNVQAAL
AVLGK
>A0A7V7D8Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MKLTERFKQGKFVITCEVGPPKGIEIDKMIDELGPLRSKIDAFNVTDLQSSVLRVGSMAT
CRLLKEKDFEPIMQLTCRDRNRLALQSDVLSAAVLGIENLLCLTGDHPQLGDHPGAMPVF
DLDSVQLLSAVKGLMNGKDMAGNDLEGTPPQFTIGATVNPGAEPLEPQIIKMEKKIEAGA
EFFQTQAVYEVDKFANFCEKVKHLNVPVMAGIVFLKSPGMAKFMNANVAGVHVPDAIIDE
LAGAGKEGRVEKSIEISARLIKELKASCRGIHIMALGWERHVAAVLEMAGL
>A0A3G8YQA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus psychrotolerans|TrEMBL
MAEPVQTAPKLTRVSVELVPRSRTSLRTELAELSSTLGNVQVVNIPDFLRYRMRSWEGCQ
MAREHVPEAIPHIRAIDINPREPLKMADFLREHGLSEVLIIEGDAPSDMSQRTYDVTSLD
IIRKFRRELPEVSVWAGLDPYRQSFTRERDYAEAKLEAGAIGFFTQPFFDRRLMDIWAEL
LPTRQVFWGATSVTTERSFSYWQNRNKAVFPSSFTPTLEANRAWAQEVLNFAAEVGGHTY
FMPIKESLSEYLGGIL
>A0A2G1ZG88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp|TrEMBL
METQKQFKRRFSFEFFPPKTDKGWEKLQGVRNTLAEVDPDFFSVTFGAGGSTRDRTVQTV
LDLHKRGVSTAPHLSCVGATRDSIAELLDVYRDNGINRIVALRGDMPSGMGAAGELRYAN
ELVKFIREYSGDTFNIEVAAYPEFHPQARTAEDDLKNFARKVEAGANSAITQYFFNADGY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCAKLLAAGAPGLHFYTLNQAEPSQSIWKNLGIGEREKIAF
>A0A3A0D776|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSLAATYAPGRFGLSFELFPPKTPQGDEQLFAHVAELVKFRPDFITCTYGAGGSTRAKTL
DIVSRVKRQYGVRVATHLTCVGSTVVDLRAYLNDAASKNVDYVVALRGDPPKGETAFRAV
EGGLRYANELVALLRTEFPAFGIAVAGYPETHQEAPSFEVDLANLKRKVDAGADVVITQL
FYDNTDFFRFEERCRAAGIRVPIVPGILPVTNFAQIQRITSLCKAKLPPAFVDALSQAGD
DDASQFEIGVDHATRQVEELVRHGVPGVHFYVLNKSQATAGVLAGVALPR
>A0A062L1P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 1571545|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A1W6WDQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcaceae bacterium CPB6|TrEMBL
MKIKNLLKPGQVTVSCEIFPPKQGTGLPHAREVVHAIAALQPAFVSVTYGAGGTNCANSI
ELAAEVEKCGVPALAHLTCVSAEKQEVLAVARRFAANGIENILALRGDLPKDDSFPRDGQ
YRHACELITDLKEMGNFCIGGACYPEGHVESANKAEDLQYLKEKADAGCDFFTSQMFFDN
DLFYNFLYRALAVGIHVPILAGIMLLTSAKQMRRCVELSGTYLPRRFLSLVDRFGSDPAT
MKQAGIAYATEQIIDLIANGVEHIHIYTMNKPDVAAKILSNLSHVISSHAD
>A0A2E6TU66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDIFAEASAEGRPVVSCEFFPTKTPEGERSLLEKTIPRLKAAGPSFCSVTYGAGGS
TRGKTLDIVEAIQNEHDLPAMAHLTCVGSTAEDIGGFLNEAQARGIKNILALRGDPPAGE
NVFVKPEGGFEFSYQLVEAIHAHGGFSIGTAGFPEGHIACTEGKDVDWQRLKEKVDHGAD
FVITQLFFDNEDFFRFRDHLRSLGMGRPITAGIIPILSGAQIRRFTDLCGAKLTPALSAK
LEELGDDNDAVRQFGVQYATEQCQGLLKAGVEGLHFYTLNKSYSTVQILDNLGLAGQVE
>A0A0F0DFD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium 26|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRNILNTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGEAFHIEVAAYPEYHPQSRSARHDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A3L7RX06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MKLKDFFSPERLQSGTRGLSFELFPPKNEELLPNLMNTVEELQRFSPDFFTCTYGAGGST
RDRTLGVLGALKTQHNLRIASHLTCVGSTVEQLRSYLDEATAIGVDYIVALRGDPPKGET
EFKQTEGGLRYANDLVSMLRREYPGLGILVAGYPEVHQEAPSAEVDLENLKRKVDSGADA
IVTQLFYNNEDFYRFRDRCEAIGIKIPVIPGILPVISLPSIQRIASMCKAALPQDFVDAL
SQSDQVDWQFQVGTDFAANQVADLLKSGIPGIHFYVLNSSKATSKVLDAVGW
>A0A2E2HPN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRLIRXILEEKRSLGETPLSCEFFPAKTPDGEKLLLQNVIPKLLAINPAFFSVTYGAGGT
TRDQTLEVVDLIQKEQEVPTMAHLTCVGSTRXDIGDFLKEASGRGISNILALRGDPPPGQ
DTFIKSXGGFEFSYELVEYXHSENRFGIGVAGFPEGHIACTEGREVDWDRLINKVEXGAD
FIVTQLFFDNADFXAFRDYLRXRGMTKPILXGXIPXLSSGQXKKFTQLCGAKLTKEISTR
LDELGDDNNAVSEFGVEYASRQCEELISNGVDGLHFYTLNKAKPTLEIVKNLGLQK
>A0A3M0XV24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MHAQDLFQRRTFSFEFFPPRSAEEAERLFHTIEELEPLKPTFVSVTYGAGGSTRER
>A0A2D5MP64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRLIKDIHSDKELLGKPTISFEFFPFKTPEGEVRFFEETLPSLMGSRPDYASVTYGAGGS
TREKTFEIVAKIQGDFGLPTIAHLTCVKHTIDEINSILDDAKKLGVRNILALRGDPPLGE
DWSMTDGGFEYASDLVSYIKAQGDFGIAVAGFPEGHIDCKDGKKVDWQYLIKKIKCGADM
VITQMFFDNSDYFQLADFLKEAGVNIPLLPGIIPVDNTSQIKKFSAMCGAKLPKKFTTRL
EELGDDLDGVREFGIEHATLQCQELLDRGAPGLHFYTLNKSKAVSSVLSNLNLA
>A0A117V2K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. Fuku2-ISO-50|TrEMBL
MTDPSPLWHPGDPADPGLPLPILPGHVSPGRFERVLRAGLFAVTTELAPPDSADPADVLT
RAREFDGVVDAINATDGSGANCHMSSLGVCAILTRAGYSPILQVSCRDRNRIAIQGDILG
AAALGVCSMLCLSGDDVSVGDHPEAKPVFDLDSVSLLDTARVMRDEHRFLSGRRLDSPPR
LFLGASINPFAPPADARVHQLAKKIAGGAQFVQSQYCFDIAMARDFLNRARDRGLLERCF
VLMGVGVLASAKTAKWLKSAIPGVHIPDETIRRLEQAEKPRAEGRRIAVEMIQQLAQTPG
VSGVHVMAYRQEEWVGEIIAAAGVLGDRRPWSPASPPFEQRTSA
>A0A349J854|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MITTLIERSEAWAKGLIFGCRACGQCVLRANAMTCPMRCPKNLRNGPCGGTLGGRCEVDA
ARPCIHVRIHTRRHHGKVEAAPIMPAVDHALVNRASLLTACSGADRGCREPLPALTSTGW
KDGEPRTASALEAALRSGRFVVTTELRAPRGADLARVRREAEALHGRFDAINATAYLGGN
PSLPSGVVARELQAMGVEAVAQVTARDTTRTTLIGELFALAHGGVHNLLCLTGDWRTGRP
MVKPVYDLDSSLMLYEARHLRDRSRIFHTGEEVAQAPRPFLGCAINPLSDPLDVPVRRLR
VKADCGAEFAQTQVLTETVRLAAFMAAASAQDLPRRVAILAGIPVVTSLKALDHLHRIAG
VAVDPGFAARLRAASDLRAAGVAEASRLCREARA
>A0A3L7N923|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MHLVDVLARDSFTASFEFFPPKNEAGWDSFFTTIKDFGILKPSFVSVTYGAGGSTRQFTH
DLVVRIGKEAELDAMPHLTCVNHSAQDIDQILSRYAEAGVSNILALRGDLPKGTSALASD
YSYASDLVQAVRAFAQSGRHPDPRGFGIAVAGYPEGHPQTPNTLVQMDHLKAKCDAGADL
IISQLFFDNHAFYDWRERCELAGIKTPILAGIMPITTVTGLKRMAELAGGTKFPAALLRA
VRRAQDDADAVSRVGIHWATEQCRDLLDHGVRGIHFYTLNRSDATRKIYENLGVSSTDAL
RL
>A0A3L7ULA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRLSQMFRTQRFVLSIEIFPPKTADGDTALRQNLQTLVEYDPSFVSCTYGAGGSTRDRTL
QWCREIQADFRRTAMTHFTCVGSTRDELLSWLDQAVAEGIHNVMALRGDPPAGQEAFKTV
EGGLSNANQLVELIRQTHPELGIGVAGYPEKHQEAPSLDIDLQHLKCKVDAGADAVFTQL
FFVNDNFFAFRDRCDEQGIRIPIVPGIMPITDFARIKRITSMCGTVFPQGLAMRLEAVQD
DPQAQFEIGVEHAIQQCEELRSAGVPGIHFYALNKSDACQRILDAMHLQEKA
>A0A538RVT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
FSFEFFPPKTDEAWEELFVNIARLQELQPSFVSVTYGAGGSTRERTHDLVVRIHRETNLT
AVSHLTCVCHQREELAAILDRYAASGIENIMALSGDPPRNLATYDRSGDAFQYAEGLVHF
IKAHASPPDPRGFGIGVAGFPEGHPATPNRLKEMEFLKQKVDAGADYICTQLFFDNRDFY
DFRERCDLAGIKVPIVAGIMPITSKKGMERMAELALGARFPARLLRSVSRCGDDASAVAR
VGVLWATEQCCDLLHNNVRGIHFYTLNKSDATRQIYENLGVKDSVALRTV
>A0A0T6LVN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces vitaminophilus|TrEMBL
MALGRPTTRTDRATTIRELISSGRRSYSFEFFPPRTDQGERNLWNAIRRIEAVSPTFVSV
TYGAGGSSRERTVRMTERIASETTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLALR
GDPPGDPQGEWVPHPQGLTHAVELVRLIKESGDFCVGVAAFPEKHPRSADWDSEIRHFVA
KCRAGADYALTQMFFHVEDYLRFRDRVAGAGCATPIVPEIMPVTNVRQIERFAQLSNAAF
PRALAEQVLAVEHDPAAVRAIGVEYATKMSEKLLAEGAPGLHFITLNHSTATLEIYENLG
LHQRV
>A0A8E5MGH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ustilaginoidea virens|TrEMBL
MDKITDKIAALPADRDYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
AAKSLELAELCQRQLGLTTCLHLTCTNMSKHLIDKALDDAKVIGIRNILALRGDPPRKEE
YRDANGHGPEDDGSADFTWAIDLVKYIRKRHGDYFCIGVASYPEGHSDESHPQGQSLEKD
LPYLVDKVRAGADFIMTQLFFDRTAYDHFEKTLREHPSGALETIPIIPGLMPIQSYQMIK
RTTKLSHARIPPAIMSRLDAVKGDDEKVKLVGVDIISELIEQIRTIKNRSPGRKGFHFYT
LNLEKAVSLITERSGLIPDAADQDEAVTDDYPRAPLALRVNGTARTSRTSSHSRASRRRS
SVGSDPYNRVIVGGRPATHPEWEATGQEAGVPAEGINSRANTLAISEGEGVLGREATWDD
FPNGRFGDSRSPAYGEIDGYGVSLHVSITRAVTLWGHPKTREDVDDVFVRHIKGEIEAIP
WSEEGLSAESSTIQPRLVEMNTKGWLTVASQPAVNGIPSSDRTFGWGPENGFVFQKAFAE
FFLPSADWRALAGKLAGPDCSGSVCFYAANARGDFASSDATGGASARTVAASTNAVTWGV
FPGKEIITPTIIEEVSFKAWSEEAFGLWGEWAKVYARGSESEAVLSAIRSDYWLVNIIHH
DYMDKDALWRLLLG
>A0A845VX40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO3I8|TrEMBL
MTNPTKNSFRTAVESGEFLITAEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQQGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFEK
KLEAGAEFFQSQLICDFDRLEKFMDQIAAGTNKPILAGIFLLKSAKNAKFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSAINDLVCK
>A0A151EEW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon SG8-52-1|TrEMBL
MNFRSNLERVLSEKKFAVTAEIGPPKGADSNKIRHKAEILRGCADAYNITDNQTAVVRLS
SMGGSFILLNLNLEPIMQMTCRDRNRIALQSDVLGAASVGVRNILFITGDHQSFGNHPDA
RGVFDLDSIQLIQIVKNMRDHGIFQSGDKILSGNPEIFIGAASNPFAEPYELRVDRLEKK
IEAGADFIQTQSVFNLDRFNVWMDEVRSRNLDKKIHILAGITPLKSLKMTERMKFHVPGV
DIPDRIYERMKNAVDPKHEGYNLALELINDIKKIKGVHGLHITALFWEDIIPHLVRESGL
L
>A0A8B8UR30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces paradoxus|TrEMBL
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPVSMIDEALENAYHSGCQNILALRGDPPRD
AENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPTKDVKLDLEYLKQKID
AGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQQ
FLSQLDPIKDDDELVRDIGTNLIVQMCQKLLNSGYISHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANKCLELWSTPTSINDIAFLVINYLNGNLKCLPWSDIPIN
DEINAIKTHLIELNKHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILNEWKLNMNKYDKPHSAHFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL
>R6QCJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. CAG:82|TrEMBL
MIDVRAHLARKPLLFDGGMGTYYKAKPGTECEQGNLLDPAGVRKVHREYLAAGAEAIKTN
TFGLPRMAAARQPDWQVLARAGWKLAAEAAVETGAAVFADLGPAPDTEAAPAGSIYTAVA
RCFVEQGAKNFLFETLSSDAGVLETVQAVKAQVPDAFVLVSFAVLPDGYTREGMYSKDLV
RRMTESGIVDAVGFNCVSAPGAMRTLVQQLGSTALPLSVMPNAGYPVVTRTQVKYQGKPE
YFAKELARIAAEGVRILGGCCGTTPAHIAALRAALDSLPAVEKAAPAVQVSTPEAPTVEK
DDAFLRKLNAGKKVIAIELDSPKDADLTNYLAGAKRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGLCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPMTVFGALNLNARNFEVELRRAGEKLENGMSGFL
TQPVLSEQAVENLRRTRETLGERAKILAGIMPVVSQRNAIFMENEVNGIHVAEDIMEAFA
GLDREQGEALGLEISLKMAREALPYADGFYLMTPFNRVALMERLIARLKTELLQEQ
>A0A497QJP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MYLGSNLLPICRTKPQKRFFQLLPTPRLAPYLSQRCGIKMHVNNSISNLPKQHFVSRMQE
GEFVFGGEIEYSTSLDLQTYRNQANFLKSHTSVLAIPDNPGSNIFLSNIAIAQVIQSLYP
YDLVLSISCRDTNRLGLATRLITAYSLGFRNLLLVTGDHPSLGSVPSSKPVFDLDSTQLL
HLCHEFNQSGTLFGNYFEKSQGIDYKLCQNADSDQDFCIIPPRLVVGTVINPQNSLPEIE
MARFQRKKTEGIDFIQTQVIFQAEAVIPLLKEFHHEKIPIMAGIVPLNNYSLAKKISNFL
PGVKFPKSLLQAYKIASQNSDNSKNKAKMFDKININYYSPLITELKHKNLIQGLYFATID
YPIIIPALIRSILNG
>R9LUJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium M10-2|TrEMBL
MNEVKEFLRFHPLLFDGAMTTFKDEKSSAEVLEQYMDAGVNAIKTATFQVSRLFSQNESL
ARQRLCEEVNAAQSVLRENVFLFGDIGPAFQGAAPFPVFQNQIDLFLEKGVKNFIFETMS
DEEGLKEACAYIKQKCPDSFVIVSFAIESTGDGMQILYDSMKDSMADAIGLNCRSGPRHM
VGHIKKLKRGNKPLFIAPNAGYPTVLGWRVHYEGTPSYFASAMEEIRKMGCEILGGCCGT
TPEHIRKVRYVLDHLPDHIDPVCETKEKKEKNPVRLDWKKKVFVELDPPKNDQVDSFIRG
VRAYQQAGADVVTIADSPIGRPRADSSLLACRIFSQTGMMPLPHITCRDRNLNAIKALLM
GLSSEGIHQVLFVTGDPLPQDAKEEVKAVYNFNSRKLMRMVSGMEELSQEMAMFGALDIN
AVNFDRQLILAKEKEKNGAIGFLTQPILSKRAFNNLKKAREQLQGFLFAGIYPIVSHKNA
LFLENEIHGMHIDSTLIERYEGLDRQQCEQLSKNVCVHIMKECVSWCDGFYLMTPFQRIS
LMKQLIEEARKILDAD
>A0A853C4G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides thalensis|TrEMBL
MATGRGRSLGELIRSGDRSFSFEFFPPKDEAGEEQLWNAIRALEPYQPTFVSVTYGAGGS
SRDKTIGITGRIAKETSLIPMAHLTCVGHTREELEEILDSYGAVGVHHVMALRGDPKEGP
RAEWTPTEGGLNYAVDLVELVRGRGDFRVGVAAFPEGHPSAESLDHDADVLVAKARAGAE
FAVTQMFFRASDYFGLVERVRARGVDIPILPGIMPILNLSAIRRQGELIGTSVPDDIVAR
ISAYDGDPAAVRAEGIKLAAELCEELLAGGAPGLHFYTLNRSKATLEIFEALRITV
>A0A524D2J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAEKKTYSKLGEALAKGEFVLTGELEPEKTTDLSHTIHEAKEMAPYVIAANVTDSPLGIV
TINSMAATKIIQDASGLECVWQLTVRDVNKLGIAGMIMGAHALGIRNVLSLTGDHPNMGD
MPESKPVFDLDSATLVKLVREMVDTGKVNGHEIEQPPTLHVGAAANPNADPMGAETLKIG
RKAEAGAEFIQTQVVYDLDRTIEFLTEIKKYNVPVLLGIFPMKSYGIAKGFDTFVPGVDV
PKDILAKWKAIKTDYKTDKAKQKEMYDQANYEFFKPFITEL
>A0A524P659|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MMTNHELPASHFLSRMQAGEFLYGGEIEYSSILNLSVFDHQAAFLDQYVDVITLPDNPGS
NIFPSNLTIAQHIQRVTSKDLILSISCRDSNRLGLGSTLLSAYALGFVNVLLVTGDHPSL
GPIPESKPVFDLDSTQLLQACQEFNEHQTLFGQKFELPVYQYQVDSEGGSEFDAEVDFGV
ELNENSSRFSPHFITGSVFNVNSSHPDLEFMKIQRKQKIGLDFIQTQIVFEVDQIISPLE
SLQSLDLPTMVGIAPMNNYSMARKVADFLPGVTFPKEILRVYRDITKNEENFQARIDKFN
AYNLAY
>A0A4D4J5J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gandjariella thermophila|TrEMBL
MERISGTRSVFSVEFFPPRDAEDEVRLWRAIRDLEPLDPAFVSITYGAGGSSRDRTIRTT
ARVAQETTLVPMAHLTAVNHSVAELRHVIGWYAAVGVRNILAIRGDPPGDPMGEWIPHPD
GVTYAAELVRLVRELGDFCVGVAAFPYGHPRSVDLDTDTDHLVGKLRAGADFAVAQLFFE
AEDFLRLRDRVAARGCQAPILPGVMPLTTVRTLRKAVELSGAPASPALAARLEPFADDPA
AFRAVGIDLVTELCQRLLAEGVPALHFYTLNRSTATKEVVGRLGLVPDRAGELTAS
>F5XX12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramlibacter tataouinensis (strain ATCC BAA-407 / DSM 14655 / LMG 21543 / TTB310)|TrEMBL
MLPISLEFFPPKTPEGAAKLRAARQRLYTLRPEFCSVTFGAGGSTQDGTLQAVTEIMAEG
VCAAPHLSCIGQSRDSIRDRLAAYAAASVRRIVTLRGDLPSGYGLGGEFRYASDLVAFIR
SETGRQFHLEVAAYPETHPQARSPQTDIEAFIAKVEAGADSGITQYFFNADAYARYVEEL
RRRGVGVPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSYGDDTASIKAFGLDVVT
QLCHQLRAAGAPGLHFYTMNQAEATLAICQRL
>A0A091ASC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenimonas metalli CF5-1|TrEMBL
MPQLSFEFYPPKTEEQRQQLDRTVGRLKKYAPRFGSVTFGAGGSTLSYTGETVRRLREHH
GLNGVPHLSCVGGTRDEIRQLLGEYKVLGCDRIVALRGDLPSGMARPGDLHYASDLVRFI
RNECGDHFHIEVGCYPETHPQAEDALADLRRFKEKVDAGADSAITQYFFNADAYFRFVDD
VRKAGLDIPVIPGIMPISNFTQLRRFSEACGAEIPRWIGKRMQAYGDDAEAIREFASDVV
AAMCRRLIEGGAPELHFYTLNLAKPTEAVISRLG
>A5DE00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)|TrEMBL
MSVVQKINSLGPQDRFISFEFFPPKTDTGFRNLLARLHRMSALNPLFITVTWGAGGSTSE
KSLDLAITCQKELGLTTVLHLTCTNTNKDIIDNALQRAKENGIRNILALRGDPPRTEEYW
TPDCDFYSAVDLVKYIKQQHGDYFCIGVAGYPEGHVEGSDTSNQNPEKDIPYLEEKIDAG
AEFIITQLFYDVDKFMHYQKLLSSSPKLKNIPLIPGLMPITTYKVFTRASKLSHSSIPHE
IESQLQNTSSDDNAVKSIGIRIITDMVDQINNRSNGAIRGYHFYCLNLEKAVASVLDQSA
VLRPIMEAPTNTISHDDAVASDDEDIEMPPKKGRRRSSIINENEVAAPGFAAVGMGHKAS
ANKALLSDKRTLVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPSLKIHSPQ
EAIAKWGTPESTKDISKVFLNYLSGKINILPWVDAPLSAETALIQEELFELNDKGWFSLA
SQPSVNGARSSDKIFGWGPSNGFVFQKSFVEIFIPKEEWSTKLYPKLKHMIDNLDITYYA
GDSSGKIQSNLPVGPDSHNSKNAVTWGVFPSQEVLQPTIIDIESFRAWNEEAFHLWSEWA
RCYKKNSVSYNLLNSINGDYYLVSLIYHNFNDETGLWRALLE
>A0A1Q4V5E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces uncialis|TrEMBL
MALGTASTRTDRARTVRDMLASGKATYSFEFWAPKTPKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATESIVADSTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPEGLAYAAELVRLIKESGDFCVGVAAFPEMHPRSEGWDQDVRHFVD
KCRAGADYAITQMFFDPESYLRLRERVSAAGCDTPIIPEVMPVTSVKQLERLGQLSNAAF
PDELKERILAAKDDPAAVRSLGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHTPA
>A0A0E9MP29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas changbaiensis NBRC 104936|TrEMBL
MTLSLSQMEEARRALDTPLFAGLPGDIGVSFEFFPPKTEKMEAQLWDAVQTLAPLGPRFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEASRAEIDAVAEEYWAAGVRHIVA
LRGDPPVAGEPFRAHPEGYANAADLVAGLRKLHPFEISVAAYPECHPDSGTQVADLDNLK
RKLDAGATRAITQFFFSPDCFFRFRDAAAAAGIESEIVPGILPVSNVAQTRKFAGLCGAE
IPGWMDRLFEGLDDRPAARQLIAATLAAELCRKLYAGGVRHFHFYTLNRAELAYAICHLL
GLRPVATAQEKAA
>A0A497TVW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium endosymbiont of Escarpia laminata|TrEMBL
MTTKRSFSFELFPPKTEKGFENLKSAVNQLNALNPEFFSVTYGAGGSTQERTFASVDWLR
EQQIETAPHLSCIGSGREEILQILDRYHGQEIRRLVALRGDLPSGTGLGSLGELNYANEL
VELIKERYGDHFHIEVAAYPEFHPQASSAQTDIKNFKRKVEAGADSAITQYFYNPDAYFC
FVEECSGMGIDIPIVPGIMPITNYVQLARFSDACGAEIPRWVRRRLEGFGDDLESIRAFG
TEVVTELCRRLLDGGAPGLHFYTMNQAAPTLKIWENLGV
>A0A8I0PHS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Pomona|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TAQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A670JN08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Podarcis muralis|TrEMBL
MVNESFGAGNGVAVLGNGAAVVRSDGSSGSDSSKDSSRCSTPVLDSERHDRLWEKMRRRQ
ESGDKWFSLEFFPPRTSNGAVNLISRLDHMGAGGPLFIDVTWHPAGDPGSDKETSSMMMA
STALNYCGLDTVLHMTCCNQTKEMITAHLQKAKRLGLKNIMALRGDPIGEEWQEEVEGFN
YAVDLVKHIRSEFEDYFDICVAGYPKGHPEAESYEEDLRHLKEKVSAGADFVITQLFFRS
ETFLKFLKDCQAIGITCPVVPGIFPIQVSCVWVLLMGFSHQASTPLGNFPGCQIYKLPRV
LLLTSVANLLKPRSLPWAVSTHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNS
SSPAFGELKDYYLFYLKSKSPRDELLKMWGEELTSEESVFEVFRCYIAGEPNKEGHKVTC
LPWNDEPLAPETNLMKEELAKVNRRGILTINSQPNINGKPSTDPIVGWGPDGGYVFQKVT
WLGTLCSSLLPFHLSNYGQRVNYHIVNVKGENITNAHEMQPNAVTWGIFPGREIIQPTVV
DPVSFMYWKDEAFALWIEQWAKLYEEESPSRMILQYMHDNYYLVNLVDNDFPLDSCLWQV
LEDMHTLLNCLAEP
>A0A6L5FL14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSLEPAIRPSRFVTPHLERRIRVSFEFFPPKTEEMEQTLWASVTRLAPLAPEFVSVTYGA
GGSTRERTHATVKRILDETALAPAAHLTCVAATRDEIDKVIRSYVDAGVRHIVALRGDPV
EGVGARYAPHPGGYRNGADLVAGIKRIASVEVSVSAYPEKHPDSPTVEADVDMLAAKVDA
GASRAITQFFFENDLYFRYLDRVRARDIDIPIVPGILPVQNFKQAKAFAVRCGTSIPGWL
AARFDGLDDDPTTRKLIAVAVAAEQVIDLVDRGVTDFHFYTMNRADLVYAICHLLGLRPE
VRAVA
>A0A8F9Z9L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. DSM 110487|TrEMBL
MKVTQRISRDRPVFSVEFFPPKDEAGEAELWRAIRRLEPLDPAFVSVTYGAGGSSRDRTI
RTTARIATDTTLVPMAHLTAVSHSVAELRQVIGAYAAAGISNVLAVRGDPPGDPLGEWVP
HPQGLTYADDLVRLVRRLGDFCVGVSAFPYGHPRSSDLDSDLTRLVAKIRAGADFAISQL
FLEPEGFLRLRDRLATAGCDDVPLLPGIMPLTTVRTLRRGPELSGAPLPPALVERMERYA
DDPAGFRAEGMDVTAEMCARLLAEGVRGLHFYTLNRSLATVELVQRLGLGARRAAPALTG
C
>A0A7V9MKE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVIDHIKQAEKTLFSFEILPPLKGKSIQSIYDGIDPLMEFKPSFINVTYHREEYVYKKR
EKGYLEKVSIRKRPGTVGICAAIINKYQADAVPHLICGGFTREETENALIDLHFLGIDNV
LALRGDPIKTEPYFMPTERGHKYAIDIVKQIVDMNTGKYLDEELDLADPTDFCIGVAGYP
EKHFEALNLKTDLLNLKRKVEAGADYIVTQMFFDNKKYFEFVENCRKMDINVPIIPALKP
IVTLNHIAFLPKTFNIDFPEDLADELIKCRTDAEVKTLGIEWAVQQSKDLIAAGVPCIHY
YTMGKSETVRNIASQVY
>A0A379MXP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas mucosa|TrEMBL
MNHVATPGAGASGASPGHDPGIHPGANPLGRWLTGPRFGALPAPAALPAPALSFEFFPPR
TEALENQLWSCIRRLEPLAPRFVSVTYGAGGTTQARTHATVSRLVRETALTPAAHLTCVG
ASCGEVDDVARQYWDAGVRHIVALRGDPPAGAPDYVPHPQGYAYAADLVEGLRRVAPFEI
SVAAYPETHPSARSAEADLDNLKRKIDAGATRAITQYFFDTETFLRFIDRALAAGISVPI
VPGIMPVSNFNQMRNFSARIGASVPDWMAALFEGLDDDAETRRMVAAVVAAEQVRLLQAN
GVDEFHFYTLNRPDLTYAIAHILGVRPSRPADPASESGVEEEGKAEAASRQAGQAGA
>A0A8C6KZA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius furzeri|TrEMBL
MVNQVQRVDGSWLSCKSDSSGTSNSGGESSKESSRCSTPVLDAVRSDRLRDKMRRRMESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEEEEGGFNHAV
DLVKHIRSEFDDYFDVCVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTF
LTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKREESVFEVFTCYITGQLNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDAVVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRV
NYHIVNVHGRNLTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLKSCLWQVLDDMFELLDAPSVQRETERRP
ELTNNVRLPHTCLRFKEYLG
>A0A3D3AR00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQRNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHKIAGIVITPHMLRVLAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVET
KKELVPQLAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIQTVPIEVRGTSSWKNWYLAIEA
>A0A7Y2BN73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MTTLQQKLERGDFVITAEIAPPLSASADALMDRAEPLRGLVDAINITDAATARAALSSLA
SAAILAGNGLEPIVQMTCRDRNRIAIACDLLGAAAQGVRNMLILHGDDPAGGDMPDAKPV
FDLDSRGVMSMARDMRDKGTLPSGREIKPAPDYYIGCADAPMNPPDDWEPKGLEGKIEAG
AQFAQTQFCYDLDIARNYFARLKQHGITGKLKFIAGIGPLLSAKQARFMDENLFGVNIPA
HIIDRLDAAQDQKAEGREICAELIMGLREVDGIAGVHIMAPMQGAKAIAESIALTGLRAR
AQ
>A0A662B1I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MIAFEEYLKENLVLLDGAMGSLIYEKGVFIDKCYDELNLSRPELIRSIHEEYIRAGARVI
ETNTYGANRFKLKSHNLMEQIEEINLTGVSLARDAAEENAYVAGSMGPSGVELEPWGETT
LEEVFEAYAQQAGIMERGGVDLYILETFQDIREMEQAIKAIRSVSDLPVVAMMTVGEDGK
TRYGVDLEDITCRLVNSEATVIGLNCTVGPKPMLDFVEQMVRLSDKPISIMPNAGRPQFT
DGRMIYMSTPEYFSVYTKRFIDKGVRVLGGCCGTTPEHISKMANALAMKQTRIQHSINIG
VRPVTKEPLPDPVPAEEKSNLSRKLISGEQVVLVEMVPPKSTDITKPLEGARLLKESRVD
AINIPDGPRASARMTGLALSVLLQNQVDIETVLHYTCRDRNLLGMQSDLLGASAMGIKNI
LAITGDPPMIGDYPQATAVFDIDAIGLVHLISNLNHGIDVGEKRIGDPTSFFTGVGLDPN
SVNSDNEIHRLQLKKGAGAEYIITQPVFDVASLESFMEKVDAGDMFLIAGIWPLVSLRNA
EFMKNEVPGVTVPDEVIARIARYETREDQLKAGIEIARSMVDKVLRFVDGIQVSAPFGRY
ALAVEVAQAILSKAK
>A0A6N7MLA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MPLLTPARRWQPAFYPFKREKLSRRLLAKIELFVKGPLYGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGATSEKCYVDETRICIWYKIYKRAAKMGREDALLEVLPPLDWDKVGTDTW
GDVVKQIRKVGIGAFFRGLLSKDDEKKSLVWDSIFRPIRQPEWWQGDSEYHPAAYDEPVS
DLERRLRNGEFVVTSEVMPPLSANSDKLIQNINIVKSYVVAVNFTDCASASPRMSSMACC
KVAHDNHAEPVLQIAARDRTRSGLQSEIIGANELGVHNVLCISGDSARIGPAPMSNLNIL
DIDSIQMLWILRRMRDDGVYLDGRKMKIPPKLFLGAATSFTLEPELQAIRDHKKVNAGAQ
FFQTNLVFDPICLDRWLEQLDKRDILNKIYILVGVIPLKSYKTAQYFHYKIPGVSIPDNI
MKRMEKAGESGQEEGIKIALEIIDSIKQKQCVNGIHLMTLGFESIVQRIITEAGLVTEKY
NPFFSKQ
>A0A8G0EG22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. DSM 110487|TrEMBL
MDLRRRILEGKGEFLLFAVTPPRRAASPERAQEIAEVTLERLRPLGLDGLVLYDIDDESD
RTSQERPFPFLPTMDPADYLSRHLSACDVPAVVYRVVGKYPEAELRSWLRAQDTDRVLSV
FVGASSRGKQVATSLAQARQLRATVRPELALGGVAIPERHTRRGDEHLRLLAKQATGCSF
FVTQVVYDVNAAKDLVSDYRYECDARGVAPVPIVFTFSVVGSTKTLEFLSWLGVDVPRWI
QNELRHAADPLVASHEQAFATALDLIAYCRRLGVPFGLNVESVSIRRAEIEQSVSLAAQL
GRELHRS
>A0A7V4I8W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MTVIELIKNAKGPLFTFELLPPLKGHSIERIYSTIERLLEYNPAYINFTTHRNEIVYRER
PDGLIEKKVVRLRPGTIALAASVKYKYNITVVPHILCGGFTMEETENALIEMKFLGINDV
LALRGDPQKGSRVFIPEKNGHKHTSDLVRQIANMNRGIYLEDSIENAEPASFCIGVAGYP
EKHFEAPNRQVDMEYLKMKVDAGAHYIVTQMFFNNDRFCRFRDECRKAGIEVPIIPGIKP
ISALNDINLLPQTFHIEIPNDLFKAVRKCKSDEEAREVGIEWAVQQSKELIKMGVPGIHY
YTLGRSDNIARIVKSSF
>A0A846Z4P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura latina|TrEMBL
MRRARPDRAPTVRELLASGGRSFSFEFFPPKTDKGARNLWRTIRELESLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPDGVEYAAELVRMIRSYGDFCVGVAAFPYKHPRSPDVDSDVRYFIEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDVPILPGIMPVTRLSTIERSEQLSGAPFPPEI
RARFDAVADDPEAVRRLGVEHAAELCRELLDQDAPGIHFITFNKSTATREVYSLLGAGEY
GARGSVPPMTA
>A0A2D8YSE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MVSATDESRLSRQPESGRPDIAVSFEFFPPKTDAMEERFWASLSRLAPLGPRFVSVTYGA
GGSTRERTLRMVSRITNETGVPAAAHLTCVGATRDQVDDVVRGYAAAGVKRIVALRGDPP
EGVGHAFTPHPHGYNSAADLVAGIRKLGDFDISVAAYPEKHPQSADWDADIDNLKRKLDA
GADRAITQMFFENGDYWRFVERAHKAGITAPIVPGVQPIHSFRQIAGFAGRCGASIPQWL
ADRIEGLDDDPETHALVAAAVAAEQVTELLDSGITEFHFYTLNRSNLVLALARLLGIRP
>A0A5P9GE01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria sp. THAF33|TrEMBL
MSKPEISFEFFPPKTLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRELTRDAVSTLHK
SSGLNVAAHLTCVDASRQETLEIADTFARAGVQDIVALRGDPPKGQDKFVPHPDGFSSSV
ELIEALAETEMFSIRVGAYPDTHPEAANMAADVDWLKAKLDAGADEALTQFFFEAETFFR
FRDACAKAGIDKPIVPGILPIENWAGARNFAKRCGTHIPLWVEQAFEKAVRDGREDLLAT
AICTELCSDLIEGGVDKLHFYTLNRPELTRDVCFALGITPSVELENVA
>A0A220SRZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp. N3-2A|TrEMBL
MKRISFEFFPPKTVQGQEKLLATQKKLLVKKPAFFSCTFGAGGSTRDNTRSMVDLLREQF
ADTAPHLSCLGQSREEIMELVNGYKDKGVKRIVALRGDLPSGMGYAQSDLKYADELVALI
REETGDHFHLEVAAYPENHPQSRSFDDDIAHFQRKIDAGADSGLTQYFYNADAYGYYMDE
LRRRGCGAPVYPGIMPILNVANLFRFSDNCGADIPRWLRGRLTDLQDDEATVKAFGEEVV
TRLCERLLAMGAPGLHFYTMNQAAPVIRVLDNLGL
>A0A2A5EFN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKLTEYINTDRSLFSFEVLPPLKGKSIDSLYHAIDPLMEFKPAFVDVTYHREEFIERPRK
DGGYDKISTKKRPGTVAICAAIMNKYQIEAVPHLICGGFNKDETENALIDLAFLGIENVL
AIRGDNLKDERNFTPEKNGNGNALELIRQISDMNNGVYQDQELQNATETNFCIGAAGYPE
KHIDAANINSDLKFLKRKVDAGAEFITTQMFFDNEKYFSYVKRCRDFGIHVPIIPGIKPI
TKKAHLRNLPKIFNMDIPEPLATELHDAKDDKAARQIGIEWCIQQCKELKAANVPALHFY
TMSFSSATKDVVSKIL
>A0A3D2HI09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTDHFKKSDKTLFSIEILPPLKGKSIQSIFNAIDPLMEFKPPFIDVTYHREEFVYKKR
EGG
>A0A0Q7MN79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. Root485|TrEMBL
MSAAAVEPRTPGLHASTRPRAQAANDRPTISFELFPPRNPDAAPRLWATIQALETVKPDF
VSVTYGASGKTRVTTRALVRRLLRETSLNPIAHLTCVGTSREEITTIVGEFLDEGLRSFL
ALRGDPPTDQSNWEAHPDGLQTAGELVELLREIEAQRCADSPSQAVRARVRPLSVAVAAF
PRGNHATGGTRAQDVASLLAKQEAGADFAITQVFFDAEDYLGIVAEAREAGVTIPIIPGI
IPTTDPARLLRVQELTGVPVPHDLLDLLGSADDELDRHRRGIRASVDLVNGVLDGGAPGV
HLYTFNQHHAALDLLEGAHLDGGARTAPDLASWPQDTAPARPPRD
>A0A1E3YAI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. SCN 61-19|TrEMBL
MTKPERPIAKTPDVRISFEFFPPKSPDMEDQLWQTVQALQPYQPDFVSVTYGAGGTTREP
TLATVKRLIADTPLATASHLTCVGATRDEVRAVVEEFQAAGVRHFVALRGDPQGGMGSRY
APHPGGFVNAADLVSGLRDLGDFEISVSAYPERHPESENDDVDLDMLKQKVDAGATRALT
QFFFDNDIFERYLERVRAAGITIPIVPGIMPIQNLTQLKRFASMCGAGTPSFLDERFEGT
EGDAQARAAVAADIAAEQIADLARRGIEEFHIYTMNRAPLTIATLERLGIAAKVDKVSNA
AA
>A0A2N6B5B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MTSNGNGKSPREAAATPEQPRIRVSFEFFPPKTEKMEETLWRSIEKLAPLEPEFVSVTYG
AGGSTRERTHATVTRILRETKMVPAAHLTCVDATREDVDEVARAYRDTGVRHIVALRGDP
VDGVGNAYQPHPEGYASTVDLISGLKRIADFEISVSAYPEKHPESPDWQTEIDLLKRKVD
AGATRAITQFFFSNDLYEAYLERVRAAGIFIPIVPGIIPIHNFTQVAKFGAATGTTIPPR
LAERFEGLEDDAETRKLVAAAVAAEQVDDLVARGVSEFHFYTLNRADLVFAICHLLGIKP
GHDAVAA
>A0A510L9J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia hongkongensis|TrEMBL
MKNKVEAGTDFLTSQMFFDNDIFIKFKEKAEKLDIKVPLVAGIMPVTNAKQIKRIIELSK
CSVPQKLDKLLEKYGDNPESMKKAGIMYASEQIIELLAYGIKGIHIYTMNKPEIAKEIMK
NIEFAR
>A0A523GW40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKITELLHNATDPQYSYEIIPPKRGGSANDLIEVVNGLIDLEPPYIDVTSHSAQVYYEEQ
AGGTWKRHVKRKRPGTLGMCAAIRGRFGIETVPHLLCYGFSREESEDALIELNYLGIQNV
MALRGDDNGYKKPLINDRTRNEFASDLVKQISDMNQGRYLENLIDSSPSDFCVGVAGYPE
KHFEAPNLTWDILNLKRKVETGAAYITTQMCFDNQQIIEFEKKCREVGITVPIIPGLKIL
TSKKQLMSLPKNFAVQIPEALAAEVESAKEGHVHEVGIEWAKKQSEELIEAGFQNIHFYL
LMTSKHVRKVVGPLRKMA
>A0A2K6UBD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saimiri boliviensis boliviensis|TrEMBL
MTVKAWPPTRPVGAAMLEAGLPVARKGGFRPVVPPRQQPDTCAAPLHCVPRPSTATGLRP
AGERSESPGTGGRNLAMVNEARGNGSLNPCLEGSASSGSESSKDSSRCSTPGLDPDRHER
LLEKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSD
KETSSMMIASTAVNYCGLETILHMTCCHQRLEEITGHLHKAKQLGLKNILALRGDPTGDQ
WEEEEGGFNHAVDLVKHIRSEFGDYFDICVAGYPKGHPDAESFEADVKHLKEKVSAGADF
IITQLFFEADTFFRFVKACTDVGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVI
EPIKDNDAAIRNYGIELAVCLCRELLASGLVPGLHFYTLNREVATTEVLKRLGLWTEDPR
RPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKNYY
LFYLKSKSPREELLKMWGEELASEESVFEVFVHYLSGEPNRNGHKVTCLPWNDEPLAAET
SLLKEELLRVNRQGVLTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEA
LLQVLKKYELRVNYHLVNVKGENITNAPGLQPNAVTWGIFPGREIIQPTVVDPVSFMFWK
DEAFALWIEQWGKLYEESSPSRAIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLN
RPTQNEREAEAL
>A0A7C1UQX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sedimenticola sp|TrEMBL
MESQKKYQPSYSFEVFPPKTEQGAEKLRLVRDRLMRLNPLYISVTYGAGGTTRDRTIGTV
LEFQEAGVNAAPHLSCIGSSRDEILELLELYRSHGIDRIVALRGDLPSGMGAAETGDFRY
ANELVEFIRAETGDHFYLEVAAYPEFHPQAPSARADLANFKRKVEAGANGAITQYFFNAD
AYLRFVESCEKLGLDIPIMPGIMPITNFTQLARFSDGCGAEIPRWLRRRLEDLEDDLESI
RALGLDVISEMCQRLLEQGAPGLHFYSMNQAEPVLGIWKNLGLPGAELI
>A0A841N117|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPSLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMKALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHKIAGIVITPHMLRVLAQEKQDGRTENA
YKRCAIQILMCKYLGFSGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVKT
GKEFVPALTHYSRRPTSSQLIKYQHLHFMHKALFESKISKGIGKFILKASFWENKAASNV
LLKTEFMSKHTVVGCESCGQCRLAETLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A383Z569|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balaenoptera acutorostrata scammoni|TrEMBL
MDGPKPKVLPAGHCCPSLGMRAWEAGSARLSVPPSISRSSAMVNEPRGHGGPSPRWEGSS
SGSESSKDSSRCSTPVLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAVDLVKHIRSEFGDYFDVCVAGYPKG
HPDSESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQALSLCQELLASGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPSINGKPSSDPVVGW
GPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGDNITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDSCLWQVVEDTFELLNRPPQNKSETEAP
>A0A840VEH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloferula luteola|TrEMBL
MHIQDILQQRRPSFSFEFFPPKSNGAWEELYRTIVELEPYAPSFVSVTYGAGGSTRDATH
DLVVRIKETTGIPPIPHLTCVGHDEAEVDAILSRYAEAGVSNILALRGDPPRNWPDYDWT
DSAFPHAADLVRFIRKFNESGRHPDPRGFGIGVAGFPEGHPSTPNRLSELEHLKAKVDAG
ADYICTQLFFDNHDFLDFRERCRLAGIEVPIIAGIMPVSTLGGMKRMAELAAGARFPAKL
LRSLERAGNDAAAVERVGIHYAAQQCSELLDQGVDGIHFYTLNKSAATREIYASLGFKPN
TEAASS
>A0A0T6AA49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CSP1-8|TrEMBL
MERILDRMKKSPLVFDGAMGTMIYERGVFINTCFDELSLSNPKLISQIHREYVEAGAEVI
ETNTFGANRIALRPYGLSEKVVEINRQAVRIAREAAGDSVYVAGAVGPCIRPDQIMPDEH
AVEVEEAFAEQIGALVAEGVDLVILETFTHLKELRLAARAAKRLGAVVLASFALNDRRET
AVGMKAGAIARELSADGNVDAVGINCGTGPAGVFDALQSVLPQVAKPVVVMPNAGFPRDV
GGRLLYLTSPEYFTEYAKKYIELGVRGVGGCCGTTPAHIRMASRAIKSLSGVKKHVEVRP
LTQQGVLVQVIPPERKSRLARKMLEGGKVTSVEIVPPRSSDLSGMLAKVKQCAEAGVDAI
NIPDGPRASARISPMIAAITILKEVGIEPILHYCCRDRNLIGMQSDLLGGYAAGLANFLI
ITGDPPKVGDYPQATGVFDVDAIGLTQVAANLNRGFDIGGNPIDPPTGIFIGVGANPCAV
ELPREIDRYFRKIDAGAEFAITQPVFDVEALFRFLDRVEGTTRRIPVIAGVWPLVSYKNA
EFMNNEVPGVVVPREILDHMARCRTKEESRRAGIDIARRTIERVSPRVSGFQVSAPLGSV
ETALAVLGKER
>A0A847GRM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Anammoximicrobium sp|TrEMBL
MSLKTTYGPGRFALSFELFPPKTSDGETALFAHLVQLVKFAPAFITCTYGAGGSSRDKTL
AVVAEVKRRFQVPVASHLTCVGSSVDHLREYLTQATHGGVDYVVALRGDPPKGETEFQPA
DGGLRYANELVALLRAEFPHFGVAVGGYPEKHVEAPSFEADLENLRRKVDAGADAVLTQL
FYDNQDFFRFRERCQQAGIRVPIVPGILPVTNFAQVQRLSSMCHARLPRGLVESLEARQD
PVSQFQVGVDYAIRQVGELIRQDVPGLHFFLLNKSQAASCVLAEVDLPPRTPPG
>A0A7Y1MM48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas gessardii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKADLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISDMCETLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A2E8Z661|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp|TrEMBL
MTTLTLPLVEACPKKMRLGPCGGVGPDGGCEIDPSHACLFLEPEWASAQAASAPVTPATH
RTAPGTSAFQDRLDSGAFGVVAEVNGPDTVDVTEFVTAAERIAEVADVVSVTDHSGATVH
MGNVAATAHLLARGLEVMPTFGCRDRNRMALQGDLLGIASLGARNALLVTGNHPEVGDSP
DATPVFDLDSPRLLQVAARMRDEGRYANGRPIEERPRLYLGATAHPFAQPYDDRPGQVLR
KVVAGADFVISQHVFDLPLWRRFVDGVNALRGDAPPFHLLGGVAILPDEPIARRVNAGLR
GFSIPEETLTRLRQARDPQAEGITIAAEIVAELDATDGVSGCLLAPVTGRSNALTASAEQ
TELIAEVRRQAGVPVPVSGAAS
>A0A2S6UNM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha3_Bin5|TrEMBL
MTQSTDYNNNVFKSNIQKFLSDFTTEVTPLSAAKISNFNTILREETKVYVTFLPGSDYED
TLRTSKRLREEGFIPVPHIAARSLPSKFFLEESLKYLKNEVNVDELLLIGGAVEQPIGCF
ESSMQVMETGLLDKYDIRKIGVAGHPEGSPDIPDTEVTSALKWKNAFSERTEAELYIITQ
FCFDAKSIIEWDQSIQREGNKLPVRIGLPGIASIKTLLNYAIACGVGPSIKFLKRQSKNV
SKLMMTNAPDKQIVALAEYWTVNPTCGLTGVHMYPLGGIKKSSDWIYAAIDGNFSMDKNN
NGFLVNY
>A0A5C8V890|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flagellimonas hymeniacidonis|TrEMBL
MKVTDHIKKAKGETLFSFEIIPPVKGKSIQELYNNIDPLMEFNPPFIDVTTSREEFVYID
RDGLLDKKLTRMRPGTLGICASITHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMREEKYFEPTKGGHPYASSLVKQIQELNCGNYLHEVIETDNCSDFCVGVAGYP
EKHMESPSLKSDLKRLKEKVDLGADYVVTQMFFDNQKYFEFVEEARKMGINVPIIPGIKP
IAVKRHLQLLPQVFRVDIPQDLVDAVEACKTNKEVRQVGVEWCIQQSKELKEAGAPVLHY
YSMGKSDNIRAIASEVF
>A0A4Q4YQ73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus sp. 5C6A|TrEMBL
MEKITDKIAALPADSNYFSLEFFPPKTAMGFANLRARLDRMARALRPLFVNVTWGAGGST
ATKSLELAEICQRELSLTTCLHLTCTNMSRRMIDTALEDAKALGIRNILALRGDPPRAAE
YQDPNGEPEDAIDENFKWAIDLVRYIRKTHGDYFCIGVAAYPEGHADESHPQGQSLEHDL
PYLVEKTLAGADFIMTQLFFDTEAYERFERILREHPSGAFGTIPIIPGLMPIQSYQMIKR
TTKLSHAKVPDPISARLDAVKKDDEKVKNVGVDILSEIVERVKEIKSRTPGPKGFHFYTL
NLEKAVSFILERTKLIPPSTPEEEEAVADVLESRVPKLEINGSTHEPPVPTKHRERRGSI
AGSDVEASIHELPMPAQDRLRRQSTIGSEPRNRVIVSEGCPSHPEYEASQAEASMLAEPI
NTRANTLAISEGEGTLGREATWDDFPNGRWGDARSPAYGEIDGYGPSLHVTNAQAITLWG
YPKKPEDISDLFIRHLTGELSAIPWSEEEFNAETATITDRLLALNSKGWWTVASQPAVNG
LPSSDPTFGWGPQQGFVFQKAFVEFFLPSAAWRVLLEKLQSAEVQDTVSWYAANAAGDFA
SSDLTGGLAGEAAKEPSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSDEAFGIFAQWAKVY
GKGSESAALLEAVRADVWLVNIIHHDYVDADALWNLLLD
>A0A368WR81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium sp. ST460_2HS_T2|TrEMBL
MKIKSIFDEKEVVFSLEVFPPRADVPIENIYQTLEELKDIDPDYISVTYGAGGGVHKNRT
CELSSIIKEKYKVEALAHLTCINSDQRTLNKILARLKAKNIDNVLALRGDKPVDGDPLGD
YNYAYQLVEHIKQQTNFGIAAACYPEGHLETESLDQDIEYLKQKVDYGVDYLISQMFFDN
SLFYKFRDKVEEKGINVPIEAGIMPVINKKQVGRIIELSDAYFPDKFQKILDKYEDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKVG
>A0A7X8YIS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio aestuarianus subsp. francensis|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASREELIQIADDYWNNGIQSIVALRGD
IPVGGGKPEMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFD
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A535EW87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKDLSKDFTQEITRRVLVCDGAMGTMLHASGISLDRPLPELNLSDPGLVRAIHDSYIAAG
ADVIQTNTFGASEVRLAVHGLGDLAPEINLAGARIALEARATASRPVFVAGSVSPAVTIA
QRGRVDHATRMDAIREQVATLVEGGVDLLIFETFGYLSELVEAVRAASTVCGLPLVAQMT
FAEDGQTLGGESPRAVAHALGELPVTVVGTNCTLGPQGLLRVVRELSRYTPLPLSAQPNA
GVPRMLGGRRFQYSVDAEYFGRHTRRYVEAGAVLVGGCCGTTPEHIRAAAAAAASQRPAE
RPGGGGARPITVSRGDQPPPEAADGGLAEQLGAGRFVVAVEVTPPVGGGAEHAAAEVMRV
RGLGGGGVHVFSVAPAISPRAQMSPLSLALHLQQRLQVEAILHVTTWDKSIMTLQADLLG
AHALGIRSVICRTGSPPLRGDYPNVDGIWEVDSVGLIELLDGLNHGRDSNGLGLEATTSF
CVGARCNPGAPDFRSELARTRAKIDAGAHFLVTRPLYELDGLRDMLSALSGRRVPVLLAV
KPLRSFSEAEELRHEVPDVTVPEAALDAMRRAGDGEEEVGIRLVEELLEEARGLVDGVVL
SIPEGSPTALDRLLQAAARAEAPAG
>A0A1J5CT78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium CG2_30_46_19|TrEMBL
MSKLSEALQSGKFVVTGEVGPPKGVSVQEMLESAKLYKGRVAAVNVTDQQSAVMRLGSLA
VCHLLKEMGIEPIFQVTCRDRNRIAIQSDLLSAYVLGIENVLCLTGDYVTLGDHPKAKPV
FDLDSVSLLQAAVQLQQGKDLAGKELDGIPKFFLGATVTPGANPLEPQIIKMEKKVKAGA
QFFQTQAVFEPRKFEEFMQTVKHLNVPVLAGIILLKSAGMARFMNKNVAGVHVPDSLIEE
MEKAENRVDTSIEIAARLINELKGLCQGVHIMPIGWEKRVPAVLGAAGL
>A0A2E4EZG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQQFNCTIKFHMGNSSLIERLSRGSLLSDGAMGTQLYAQGITGVPIEAANLERPEIVKAI
HRSYLQAGSELIATNTFGANSSRLASHGISSQTEELNRTGVALAREAIRLNGQQAWVAAA
MGPLAVDSFAAEILGSAAAHNVFAEQASILTESGADVLILETFTSLTQLRLALDAVRSVS
NLPLMATLTFNNDGLTPAGDTPEEIATTLNESSLLAIGANCSIGPDLLRSVIERMAQNTN
LPLIAQPNAGLPSYVDGQLQYTAESSYFAEVLKDIAYSGATILGGCCGTTPKHISSVRDK
IKGVIPQRTFAKIPXAPQKHSKHEDEGKPATGLAEKIAKGEFVVTVELSPPRGFDISDTV
DKLRGIAGHIDAVNVADSPRAQGRMSALATGSLIQSKLGIESIMHAAIRHRNLLAXHSDL
LGAHALGIRNVFTVMGDIPQSGDYPQATAISDVTASGLIRXMSGFNNGVDANGREIDSPT
SFFIGAAFNFNAPDIDRELKVLERKIAAGAHFLLTQPIYSMEQFDRVYSVLGKFPVPVIL
GVLPLRNTRHALFLHNEVPGIFVPGDIVKRLEQAGDKSASIGIDISKELLQELSGKIAGA
YFMPPFERFSVVQETLEGLNL
>A0A8G1D1V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 2hn|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYQAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFETDLANFVHKVKSGADSAITQYFFNADSYFY
FVERAQQLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7S8FC57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrospira kreftii|TrEMBL
MSREPQRLIDVLNRGTFAVTVEYNPPKGTNISSVLDSAKQLVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGKDMMGNKLDGSTAFTIGAAVTPEADLVGPVLAKFEVKV
KAGAQFFQTQAVYNPDVFAGFMKQVRPFNVKVLAGILVLRNHKMAEFMNANIPGMSVPKE
MIDELKAAGDRAEDVGVDIAVQSIKAVRPHCDGVHIMAIKATHRLAEIITKAEIG
>A0A7J9Y059|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonosporaceae bacterium|TrEMBL
MRNARPHALADLLRSARYEVIPAGGIEESVLAAVPRTVTITVTASPVKGLDTTLDLTERL
IRHGYQVTPHLSARLVRDERHLKDIVDRLLAQGVADVFVPAGDADPAAGKYDGALGVLAE
LTAMGRPFPHVGITGYPESHPAIDDDVTIQAMWDKHVHATYIVSNLCFDHRALGHWITRV
RRRGVSLPIMVGIAGPVERTKLLKVAAKIGVGESAKFLSKRPSWLLRFAAPGGYNLDRLL
DRCTPVLTDPWSRVAGLHVFTFNQVAETERWRQRAPHMNPAPA
>A0A536AEN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQHDFLEQLQQRPLLCDGAMGTLLYARGIAYERCFDELNLTRPALIQGIHSEYISAGAQI
IETNTFGANRAKLEAYNLEGRVRDINRHAVKLAREAREISGQSVFIAGAVGPSGRPLQAP
DEQRLSELRAIFREQIDALLVGGADLLILETFSSLAELRQAVLAAQDVGGLPIVAQMSFY
EDGHTLSGQSPARVAAVLNDLGIDVMGANCSVGPAATLDVLQEMIAAARLFLDNEQAIPQ
MFSAQPNAGLPTRIGNRFFYMATPDYFADYAVRFARAGVQLIGGCCGTTPHHIAAMRKAL
NDAYGAATPSIPGSSRETLQAKPVEITNGKVTIAGLIEEEVILPQQGTKTRLQEKLAARE
FVVSVELDPPKGLNPAKILEGAAMLQKVGVDCINIADSPMARVRMGCIALARLIQDHLGI
ETIIHFTTRDRNLMALQSELLGAHALGIRNILSLTGDPLHVGDYPNTTGVWDLDSVGLIQ
VLRRMNEGHDAAGSSIGAQASFHIGMALNLNMTEQETEQEIDKYRRKIEAGAHFIMTQPI
YELARLERFLARAGKPPIPMLLGCIPLHSSRHAEFLHNEVPGITIPDDVRSRMRAAGDQG
HEEGLKLSQELLTSARSMIEGVYLMPSYGRYDVVSKLTKMLQMQPTP
>A0A535S693|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MEASTAPDRRAHPFLERLAQGPLLGDGAMGTQLHARGVSFERSFDELNLTEPKIVEEIHR
AYISAGAELIETNTFGANRIKLARHGLETRVRDINFRAVKLAREAREISGEPVFIAGSVG
PIGQQLEPIGRIGIARATAAFEEQIAALLEGGADLLVLETFTNLPELLAAVSAARKTADL
PIVAQMTFAEDGLTLSAEEPSQVVQALERAGVDVIGVNCGVGPQVALQVLEAMRQQTRLP
LSGQPNAGLPARVEGRFFYFATPEYFATFARQAADLGVAYIGGCCGTTPAHIAAMRAALR
PVGATAPIPRRPASTAIPVDLNPAEQLPPTPFARRLADRAFVVSVEIDPPRGLNPSKCVA
GAHLVREAGADAVNIGDSPMARVRMSALSLALMIQAQVGIDTLIHFTSRDKNLMALQAEL
IGAHALGIRNIIALTGDPPRIGDYPSATGVWDVDSIGLIKILQRLNDGYDWLGTSIGRPA
SFTIACAVNPSAEDLDHEIDRFRQKIDAGAHVAMSQPLYDRRTLERFFERTGPLPIPFLL
GVLPLQSSRHAEFMHNEVPGIVVPEQLRERMRQAGENGIAEGLQQSRELLEDTRDLVQGV
YLMPSFGRYEVVAELVRWLRGRRVTTGAGTPGPAN
>A0A536K9F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAADKKRSNPFLERLRRGPLLGDGAMGTQLHARGVSFERSFDELNLTEPKIVEEIHRAYI
SAGAELIETNTFGANRIKLARHGLEGRVRDINFRAVKLAREAREISGEQVFIAGSVGPIG
QQLEPIGRIGIAQATAAFAEQIAALLEGGADLLVLETFTNLPELLAAVAAAQQTADLPIV
AQMTFAEDGLTLSAEEPSQVVQALERAGVDVIGVNCGVGPQVALQVLESMRQQTRLPLSG
QPNAGLPARVEGRFFYFATPEYFATFARQAADLGVAYIGGCCGTTPAHIAAMRGALKPAG
TATRIQRPTPSTAIAIDLNPAEQLPPTPFAQRLVAKSFVVSVEIDPPRGLNPAKCVAGAE
LVKDAGADAINIGDSPMARVRMSALSLALMIQQQVGIDTLIHFTSRDKNLMALQAELIGA
HALGIRNIIALTGDPPRIGDYPSATGVWDVDSIGLIKILQRLNEGYDWLGTSIGKPANFT
IACAVNPSADDLDHEIDRFRQKIEAGAHVAMSQPLYDRETLERFFLKTGPLPIPFLLGVL
PLQSSRHAEFMHNEVPGIVVPQQLRERMRRAGENGIAEGLSQSRELLQDTKDLVQGVYLM
PSFGRYEVVGELVRWLRQASISPVR
>A0A2E9TW79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTVKDKFIFGVEVETTRGLIKDLSVDTRINHAIEMSRSGHLDFLAVTDNPGGSSHIQPEF
LAQKLSGVDINLIVNVSCKDSNRNAIGSRLWTLASEGIFDILALTGDYPTEGYSGSSQPV
FDIDSVGLIDLMRSMSLEMENNGEKTLFNPGCVVSPFKLTEAELMTQLYKLDLKLKSGAK
WAVTQIGYDSHKLYELKNWFKQKSINRPLIGSVYILNRGSARFFNKWGIPGVYVSDSLLK
IAENQATARDKGKKYFNEFAARQISVLKGLGYSGVYISGKPTPQRLDEIINIYNSYSKND
WKQFADAINFPQDDEFYLYRKPKTFNTYHSEYSEKYLESSKKARTFKQRLKSPIRYRIGK
FIHDSFFSIDAKGYKIGHVFYKYVRGKKRTSQAFHALEQLSKVSLYGCKDCGDCSLPDIA
YLCPESQCVKNQRNGPCGGTRAGMCEIPDKECIWSRAYXRLKPFGXETNMLXRPVVFRDS
KLNGTSAWSNTFLGXDXNTKKNXIR
>A0A6B1GI32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAHPFIEAIRERVLLADGATGTVLRERGWRGPSPLAVLEDPGRVRTLHEEYLRVGADLIL
TDTFEATRIQLARHGYGERVRDVNFQAARIARDAREIIGTPAFIGGSVSPFGRDLAVGSV
TPQAAGEAVREQVGALVEGGVDVIVLETYPSLEEVRIALEAVRAVTDLPVIAALDFVAAL
TTPAGESPREVAELLAAEGGADVVGVNCGVGPRATLDILQELAAAGIEAPLCVKPNAGLP
RITGGQPLYPSSPEYFANFALRAKDLSAAVVGGCCGATPEHIRAMREALDGASAGGANGA
SDGGGVPLAVTDTRGGGLDTGLPPADEPSEGTDGEPVGEPDARLRDKLAAGAYVVSVEID
PPRGINPRKAVEGARLLREAGADAINIGDSPMARVRMSALALAVEIQREAGIETIIHQTT
RDRNLMALQADLLGAHALGVRNVIALTGDPPPEASQSSAVWDVDAIGFIRILKRLNEGVD
VAGNSLGRPTDFLVACAANPTAGDIPVELGRVRAKLDAGADLLMTQPVYDLATLEEFFER
LGTVEAPVLLGILPLMSSRHTEFIHNELEGVIIPDAIRERMRAAGEAGADAGLEIATEQI
EEARALDWVSGVYVMPSFGRYEVAAALVRQIRAR
>A0A2W1AS93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGTELYTRGLQTFDQCLDELNLLSPDMVLQVHLDYLQAGAELLETNTFGANRLRLEPYGL
SDRVSDINKKGAELAREARRLTGVTAWIAGAIGPTGRALAPLGPLTRPQAAETFREQIES
LVEGGVDLLIFETFSSLGELEEAIGAAQAACDLPIVALMTFTEEGNSLYGNTPSEAAQRL
RELGVDVVGANCSVGSQSMVETMEQMAKATDGMLAAQPNAGFPHYVGGRHVYMASPEYMA
DHARRLVELGVAIVGGCCGTTPDHIAALREAVATPLRRPARRPATTKPSVPEPDRSTPAI
SVPDLEPTGLAKKLGVKFVVTLEVDPPKGFDVGPILERLRPLQGTGLLDAVNIADNPRAQ
GRMSALATSALVQSRLGLETIMHLATRHRNLLALHSELLGAHGLGVRNLFLVRGDPPSLG
DYPQAGALSDVTPTGLLRLIEGFNRGASALGQTLDRPTSFVAGAALNLAASDMDREMRLM
ERKVEAGADFFLTQPIYDPEIVELWRKRLGAFPKPVLLGVLPLRSLRHAEFLHNEVPGIV
VPEQVRDHLRRAGQGEGEVGLELARELLRAAAAHVGGVYIMPPFNRYQIVAELLDGMEDA
ISGLASA
>A0A6L7TTS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGATLDLGRGIEAEAELAVRKVEAGADFLISQPIFDPDDAHRFRDSYERQGGSPLAVPVF
FGLQILEQGGVLFSSVPDSVRAELDAGRSSVDIAVGLYGRFREAGLNDVYLMPPIRRGGA
RDYGAAREFFRRLVSQLPSI
>A0A536NIZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSTGTSSERSRFHERLARGPLLFDGAMGTLLFSRGIPQRACLDELVVTRPDLIGAIHREY
LEAGADAIETATFGANRIRLAGYGLAAEARMFNRRGAQLAREARDVSGREVLVGGSIGPL
RGPTHGPAGYGERIIREAFREQVEGLLEGGVDLFVIETFSELEHLLLAVDEARKASAIPI
IAELTFGEELALTDGTTPEAAAAALIEAGVDALGVNCGVGPQACLDALERTGRGDARIAR
SIMPNAGLPQRVEGQFVYAAGPDYFGRMVPLALGAGAAIIGGCCGTTPDHVRAMRASLDG
TVARTAADMAREEARSRGLSSGIDRGPSSGPRTAIAESAAPHAVGEGPPATPLLAKLNEG
RYVISVEIDPPRSIRIERTIEAARLLKSAGVDLVNISDSAMARVRMGAMAVAFGIQHDLD
LECLVHFTTRDRNLMAIESELLGAHALGVRNIIALTGDPPRVGDYPTGTGVWDVDSIGLI
EILARLNRGEDQAGSPIGQQAGFTIACALDPTAADQATEWERLERKLAAGAHLIMTQPLY
DIAQVEAMDARARERFGQGGFPLPLLLGVLPLQSARHAEFLHNEVPGITIPEATRAALHA
AGDGGAEVGLEMAQTLLEQAEPLVHGTYIMPSFGRYAQAAELVRRIRDRQAARVSRATSA
G
>A0A535PTV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQHDFLEQLQQRPLLCDGAMGTLLYARGIAYERCFDELNLTRPALIQGIHSEYISAGAQI
IETNTFGANRAKLEAYNLEGRVRDINRHAVKLAREAREISGQSVFIAGAVGPSGRPLQAP
DEQRLSELRAIFREQIDALLVGGADLLILETFSSLAELRQAVLAAQDVGGLPIVAQMSFY
EDGHTLSGQSPARVAAVLNDLGIDVMGANCSVGPAATLDVLQEMIAAARLFLDNEQAIPQ
MFSAQPNAGLPTRIGNRFFYMATPDYFADYAVRFARAGVQLIGGCCGTTPHHIAAMRKAL
NDAYGAATPSIPGSSRETLQAKPVEITNGKVTIAGLIEEEVILPQQGTKTRLQEKLAARE
FVVSVELDPPKGLNPAKILEGAAMLQKVGVDFINIADSPMARVRMGCIALARLIQDHLGI
ETIIHFTTRDRNLMALQSELLGAHALGIRNILSLTGDPLHVGDYPNTTGVWDLDSVGLIQ
VLRRMNEGHDAAGSSIGAQASFHIGMALNLNMTEQETEQEIDKYRRKIEAGAHFIMTQPI
YELAPLERFLARVGKPPIPMLLGCIPLHSSRHAEFLHNEVPGITIPDDVRSRMRAAGDQG
HEEGLKLSQELLTSARSMIQGVYLMPSYGRYDVVSKLTKMLQMQPTP
>A0A7C1PM18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MIPDNQTAAARLRAVLAAGRFVVTCELECPRNASAANVERQARGYAPYVDAVNCTDNSAA
IVRMSPVAAAAIVARTGLTPLVQLTCRDRNRIALQSDILGAVAVGAAGIVAMTGDPPGTG
NHPDAKTVFDITSLELMRVARGLREGHFMSGDPVRPAPDLLVGGVENPAEGERSVSRLAA
KVEAGAELIQTQITFDVEAFARWMEQVRAAGLHERVRILAGIAPVRRPSIARYLHEHVPG
ISVPAPTLARLESAANPEAEGVRVAAEVLAAVRGIPGVAGVHLMTFGWVEGVARVVQAAG
IERTPAQGVD
>A0A535M6A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MEGPRINPFLSRLARGPLLGDGAMGTQLHLHGIPFERCFDELNLTEPRIVEEIHREYIRA
GAELIETNTFGANRIKLARHGLEAKVRDINLRAVKLAREAREVSGEPVFLAGSVGPIGQT
LQPVGRITLAEAQATFREQIEGLLEGGADLLVLETFTNLPELLAAVQAARAACDLPLVAQ
MTFAEDGLTLSGEEPSQVVTALEAAGVDVIGVNCGVGPQVALQVLETMRPLTRLPLSGQP
NAGLPARVEGRFFYFASPDYFADYAARAAALGVAYIGGCCGTTPAHIAAMRAALSPKTMA
QLARPVRPEPAIPLDLAPTEELPPTPFGQRLQERRFVISVEIDPPRGLNPAKCIAGAELV
KDAGADAVNIGDSPMARVRMSALALALMIRQQVGMDPIIHFTSRDKNLMALQAELIGAHA
MGVRNVIALTGDPPRIGDYPSATGVWDVDSIGLIKILSRLNEGYDWLGTSIGKPAAFTIA
CAVNPSAEDLETELDRFRQKIEAGAHVAMSQPLYDRKTLERFFQRTGPLPIPFLLGVLPL
QSSRHAEFMHNEVPGIVVPQALRDRMRKAGESGIQEGLAQSRELLEETRDLVQGVYLMPS
FGRYEMVAQLVRWLRETVKAPTG
>A0A536M257|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVMHYTTRDRNAMAIHSDMVGAHVLGIRNILCLRGDPPSVGGYTDIVGVWDVSAVGLMRF
LKLLNDGVDFTGKSVGRQASFVIGGSANLNADPLEPELRLMRRKVEAGAHFFVTQNVFEE
KKLETFLDGAAKFKKPVIVGVLPLANSRHAEFLHNEVPGMFLPDKVRERMRKAGEERGPK
EGQAMARDTIALCREKAAGVYLVPSFGRYELVAELVAELGR
>A0A521UFH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSRLKEALESGRFTVTAEVGPSKGVHTAPLLEDAEAISGEVDAINVTDQQSAVMRLGSLA
VCHLLVEKGLEPVFQLACRDRNRIALQSDLLSAHVMGIENVLCLTGDYVTLGDHPQAKAV
FDLDSVSLLETARQLQEGRDLAGKELVGAPRFYLGATVSPGANPLEPQLVKMERKVQAGA
RFFQTQGVFEPQRFEVFMRDAKDLGVPVLAGIILLKSAGMARFMNRNVAGVHVPEALIEE
IDGAGDKRQASIEIAARLISELRPLCQGVHIMAIGWEKLIPRILETAGLPASIKG
>A0A1F7ZM36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus bombycis|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRQKYGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYL
VEKTQAGADFIMTQLTYDIEAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVQIPPQILSKLEAVKHDDDSVKRIGVDIISSLVDGMRDIPCPGIRGFHFYTLNLEKT
VSFILERCDLIPPYSEDFDAIEEGDDISAMDGAQLRSLTRRRASSINSLPHNRVIVDKLH
ASEASSKASISHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVPPSVAHRIWGFPVSREDISALFRRHVSGELHMVPWSEGGAEEGSS
GLNAETEIIRPELLQLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFF
CPSKDYHSILKPLLQKHGHEKLAWFAANVKGDFESSLPAQTSDADPIEMNPNNVNSVTWG
VFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNETKDDVWLVCVVG
QDFGAGTEMGSEEEEDEKKFMWRVLLNAK
>A0A536CXI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSGLAALLKAGEFVVTAELNPPKSASAEVVRRRASALKGAVDAVNVTDSNRAVAAMAAIP
AAILVRESGVEPIVQMTGRDRNRIALQADVLGAAALGLENFVFMSGDDPKQGNHPDAVNV
KDLDGVGLVKMAAGMRDGKFISGDEIRYAPSYFVGATASPFAKPMSADITKTIEKVEAGA
EFLQTQPVFDLATFSQWLAELRRTDAREVAIIAGVLILRSGEQAYRLAKVPGVALGPEVV
ERMKKAADGEAEGVAIAVEMVRALKALPGVRGVHLYAIEWPEAVPQVVERAGLLPRPEAK
VAVS
>A0A3B9M9K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIVDLLTRGRPTVSFEFMAPRDETEVEVLEKTVATLAGHAPDWVSVTYRLRTGEKTLEL
VTRIKRHYHIEAMAHLTCANSRDETRRILNWMEREGVANVLALRGDPPGPGEPFQPADPE
LKHGSDLVAFVRGNGYRLGIGAACSAEKHPESPDLEHEFRYLRLKVEAGADFLITQMFFD
NRFYFDLVARARAAGITVPIVPGLMPVPSRRSLAFVTQMSGATVPDALQAEIDAAADDDA
IRRLGVDHCIKQCVQLLEAGVPGLHFYTFNRARAPIEILGTLRGQQLLAS
>A0A552WS24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Georgenia yuyongxinii|TrEMBL
MSTSSLLSVTTATHPTVSFELFPPRKPELYEAVWQRVLRMAEAGPDFFSVTYGASGSSRE
ASGELVRRLLAETSVPPIAHLTCVGADREQLAARVRGLLRAGVRDFLALRGDPPDGQTTW
APPAGGLARSSDLVALIREVEAEELGCGPAARSGAAGEPPSVVAQDLGVVPADAVSVAVA
AYPSGTSHTREEELVALREKQDAGADFAITQVFYDADAYASLVADARDAGVHIPILPGIL
PLTDPRRLHRLEALSGVPVPADLDALLRCDDDAERQRRGIDATIALIDGVLEAGAPGLHL
YTFNQDRPALDVLEHLRAGGLRNPALLTPPAGQRQSAAG
>A0A5N0V4H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis acidicola|TrEMBL
MTSVLERLQGDAPVFSVEFFPPRDAADEAVLWKSIRQLEPLDPAYMSITYGAGGSSRDGT
IRNIARAATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGDWV
AHPEGLKYAEELVSLVRSLGDFCVGVSAFPYGHPRSPDLETDTKYLVRKFKAGADFGIAQ
LFFEAEDFLRLRDRVAAAGCDAPLIPGVMPLTTPRTLHTTIKLSGAQCPQQLLDRLEPLS
EQPKAFREEGMNVVTELCERLLAEGVPDLHFYTFNRAKATREVVHRLGLVPARA
>A0A535FKA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTDEETDSEIEKYQKKIDAGAHFIMTQPIYELAPLERFLSRAGKPPIPMLLGCIPLHSGR
HAEYLHNEVPGITIPDEIRTRMKAAGEHSHEEGLKIAQELLAEAQNLVEGVYLMPSYRRY
DIVAELTKTLRAKYPKK
>A0A2E5J3R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKISNYYDLAQTTISFELFPPRTDKSARDLEERLPRLISLEPSFITVTYGAFGSDQNRTL
EIASKIRNEYQMDVAHHMTCVSSSKEDIDQLLAQIKENNIDNIVALRGDKPXTSNIFSPP
ENGFSHANELVAYIREYGDFGLAVAGYPEKHIEAEDFETDLFYLKKKVDAGADVIITQLY
YDNDHFYDFLTKCRDIGIDVPIIPGLMPILNLEQIKRITRICGATIPRDLLAKLEDAKDD
PDKLHEVGIEHTTNQALNLIQNGVTGIHFYVLNRYFHIAEIMXRIKPALQN
>A0A536H502|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLARSKPSISFEFMAPRDETEVDVMERTVAALAGHAPDWVSVTYRVRTGEKTLEL
VTRIKRHYHIEAMAHLTCANTADRTRQVLNWMEREGVANVLALRGDPPVSGEPFEPADPK
LVHASDLITLVRGSGYRFGIGAACSTEKHPESPDLEHEFRYMQLKVDSGADFLITQLFFD
NRFYFDLVARARAAGIKVPIVPGLMPVPSRRSLAVMTAMSGATVPPDLQSAIDAAPDDDA
IRALGVRHCIAQCAELLEAGVPGLHFYTFNRARAPIEILAALRGQQLLAS
>A0A535KGU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLHRSRPTVSFEFMAPRDETEVDVLERTIAALAGHGPDWVSVTYRQRTGEKTLEL
VTRIKRQYHIEAMAHLTCANTADRTRQVLNWMEPWRTRSSRTPAT
>A0A536BE49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNRERSFLLSNLASLLRQGEFVVTAELNPPKSASGEVVKRRAGVLKGSVDAVNVTDSNRS
VAAMAAIPAALLVREAGVEPIVQITGRDRNRIALQADLLGAAALGLSNFLFMSGDDPKHG
NHPDAVYVKDLDGIGLVKMAVTMRDEHKFLSGDEIRQAPEYFIGATASPFAKPMSADLEK
TVEKVTSGADFLQTQPVFDLATFSQWLAELRRVGGGREAAVLAGVLVLRSVEQAERFGRV
PGVALGQEIVDRLRKAADAEQEGLAMAVEMVKSLRALPGVRGVHLYAIEWPEAVALVAER
AGLLPRPKVKESKP
>A0A536NQZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MIAGPPVKPSRLRLDSASREALTRFLSHPRYEVLPTEESGDLVMRNLPTEVTITVTSSPR
RGIEATLALAERLAGGGYAVVPHLAARLVRDEPHLKEILARLDAIGGRVFVVAGDSQEAA
GAFPDSVSLLEAIASHAPAMKEIGVTGYPERHGFIDDDLTIQAMWDKRRQATYIVSNLCF
DVRVVKNWVARVRKRRVPLPIFIGMAGVADPAKLLRVSTRIGIADSARFLRGHTNWLMRL
IQPGGYAPDRFATGLMPELARPDMKVAGIHVFTFNEIEPTEQWRQQMLARLS
>A0A1C7PCK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia glycaniphila|TrEMBL
MSDTVAKSCLFDRTPCFSFEFFPPKSPAAAESLHRTICELEPYSPSFVSVTYGAGGSSRE
LTRSLVERIQQERQIPTVPHLTCVGHTEEELENIIEGYVRVGAKAVLALRGDPPRQGGYD
PSRDAFHHAAELVSFIRRWEERNRIQEPLTIGVAGFCEGHPDTPNRLKEMDYLKAKVDEG
ADYICTQLFFDNHAFLDYRDRCRLVDINVPVIAGIMPITSINGMQRMAELSGGTCFPARL
LKALLRAGGDPSAIEQVGIQYASSQCAELLDAEVDGIHFYTLNQSYATREIYRNLGLASS
PGKAAREAAASLQQKLS
>A0A2E5HTA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPXIXDLXNSTEXDPVFICDFSPPRSXDVSKLEPAKDLIADVISIAYSPGRSPCPXTLAS
SIWITQNTKSQSLMNLTTRDMNKLXXQXKLLGAEMLGVNNILAIQGDQFSTNENPIVKTV
NDYTPTSLLMDVNNLNRGLDFKGNKLNAPTNLCVGTSINPNKXPNTETXLTYKKXSSGSK
FFITQPVFNIQKTLDFQKLFSEKFNSXQIPNVFWGIQILSXDNFSFSPIPENLTRDISKG
XXGXDIAIEQIQILXLXKMNFIYLIPTIHSNGKRDYHSAXKVIEFFKS
>A0A1D2JMP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccidioides brasiliensis|TrEMBL
MTTTKATIAMERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKARLERMSQALRPLFVN
VTWGAGGSTVSKSLELAEMCQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILAL
RGDPPRSEEYNIDGEDDSNKDFTHAVDLVRYIRRMYGDYFCIGVAAYPEGHSDESHPEVQ
DPARDLPYLVEKRKAGADFIMTQLIYDLEAYKRFEEMLRNHESGVFKTIPIIAGLMPIQS
YHILTRTTKLSHAKVPPDIMARVEEVKADDEAVKQIGIDILCEIVNGIKNLPCPGPRGLH
FYTLNLEKAVAFIVERCNLIPTSSEPSSDSDTELDSAVFITPGMKNGVPLISKRRASSLN
SQPHNRLIVDHPASLSIGAPSSQTSTTHETQALGAGMLALNPPHQSTALQISEGMGALGR
EATWDDFPNGRWGDARSPAFGEIDGYGPSLHVNANVARQLWGYPTSREDINKLFHCHVSG
ELHIVPWSEGGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSDHPIFGW
GPRGEGFVFQKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGTT
GLDDAVPDYSGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFRIWDEWRRIF
RRGSPTEQLLDQLKKDAWLICVVGQKFGAGCGGKEASEAEKFLWRVLAGKEDTEANPTGL
Y
>A0A4Q0IY90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Isolate-002|TrEMBL
MTIPQIIASTPGRGFSFEVLPPLKGKSIETLFRGIDKLIEFNPRYINITTHRSELVFKQT
DGGLYQRVTQRTRPGTVAVASAIQNRYKIPVVPHIICSGFSKIETEYALIDLSFLGITNI
LVLRGDKAKHDSKYTPNENGYMHATELQQQINDFNNGYFIDGTSMDTGRDRPFSCGVAGY
PEKHEEAPNFDMDLQYLKTKVDNGADYIVTQMFFDNAKYFNFVDRCRAIGINVPIIPGIK
PITNINQLSILPKVFKVDIPTEFASRLLACTTDEDRKAAGIEWGIKQVNELYEGGAPSIH
YYSLNATDSVREIVRNTLH
>A0A2E6WRN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNNLQNKIKDKIFLVTSELNPPKGTDLSTLFNKVELLKKSITAFNITDNHTSKMSMSPIA
VANLLKTQEIEPIVQLACRDKNRVALQSDILGLSALGIKNILCMTGDHSSIGDDPNSKPV
FDLDGISLLKAVSSLRNGKDLANNKLKGAPEIFSGAVANPGSNDIQKEIDRMKQKIEAGA
QFFQTQPVYDIKKFESFFNQTKELNIPIIAGHIMLKSADMANNFNKNIPGVSIPQSIIKN
LSEASDKKSKSSNIAIELINELKNMCQGIHLMALGWESLIPNILKETEIKSNL
>A0A806J595|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum 16|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHADHPVYILGTIGGLAGDTDATVQR
ATPATIAASVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFVGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A7X6QG72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MQVIDILNQAKRPLFTFELVPPLKGGDVQTLLETVRQLSRFEPAYINVTNHQQEVVYIER
PDGLLERRTVRKRPGTIALSALIQYTFNIPVVAHLICGGMDQDELEDALVELNFLGIENV
LALRGDPPNGEKRFVPVKGGYEHSSELVSQISDLNRGKYLDQDLQNAQKTHFCTGVAGYP
EKHAEAPNLERDIEMLKYKVDCGAHYIVTQMFFDNAVYYRFVDACRKAGITVPIIPGLKP
IGSKRDLATIPQTFHVDFPSELVELLSKATKLSEIREIGVHWCTLQTKDLLAHGVPGVHF
YTLGKAESVASVVRSCY
>A0A6G6YK50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. POL2|TrEMBL
MKITEHIKNANGKTLFSFEILPPLKGQNIQSIFDAINPLLDYNPAFIDVTYHREEYEYIE
RHDGLLEKRVVRKRPGTVGICAAIQNKYKVDAIPHILCGGFNREDTENFLIDLDFLGIEN
VVALRGDAVKSEIYFKPEKNGHANASDLVLQIQGLNSGNYLDESLENSCPTNFCIGVAGY
PEKHMEAASLSQDLHYLKKKVEAGADYIVTQMFFDNQKYFEFVDKCREEGINIPIIPGLK
PLVTKSQLSMIPHRFKVDIPNELVIEIAKSKDNKAAKEIGIEWCIQQSKELLEKGAPVLH
YYTMGKSDVTKKIASAVF
>A0A7X8K9E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MRVTEIIQASKKPLFTFELVPPLKGRTLEPLMETIRTLMEFDPSYINVTNHQAEVVYIER
EDGLLQRKTVRKRPGTTALAALIQHTFNVPTVAHLICGGMSREQIEDALIELHFLGIDNV
LALRGDPPAGEKRFIPMPDGHAYSSQLVGQIVDLNHGRYLDDQYSDGEATRFSIGVAGYP
EKHAEALNMTVDLANLKKKVDAGAEYIVTQMFFDNGKYFSFVNACRSIGITVPIIPGLKP
IASKRDLSLIPQTFGVDLPEALTSELEGVDSNAEITEIGVQWCIAQSKELYAAGVPSIHY
YTLGKARNVARIVRAVY
>A0A7U4TIR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfofervidus auxilii|TrEMBL
MKTALSKGQFVVTAEFYPPKEANGSEIKERALVLKDVVEAVVVRDNPLAQVHTSPIATAT
LLLNVGLAPIVQISIRDKNRLAIQSDILGAVTLGVKAFFCLEDCHQRVGDNPGAKGVFDL
DCVQLISIMKKIEHSLVGTRINPFAHPLELHLINLSKKINAGVDFIQTMPVFDLERFKEF
ISLIKGENLYLLAGVRPIKSWQALQSTSQMVIPENIVQRIKNTPENKQAEEGIKICVEII
KALKQIKGVNGIHIFAHDWEEAVPILVRQANLK
>A0A8F8I8D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. S7/73|TrEMBL
MIRKRTKFKLHDISTSPAIAASIEASPAQVLGPASLAGIFPQGVRVYLTDTGQASQDRLV
DAAKHLRDLGYTPVPHLAARRISSRVQFEEQVKRLAGEAGVSDVLVVGGGVATPAGPFTS
SMDMLSTGIFDRCGINQIAIAGHPEGSPDFSDETATAALKLKYDFAERSDAAMRIVTQFG
FDPARFIAWAEGLAASGIDLPVHIGVSGPARITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESVVGPIERHWQANPAGPIRQIHVFPFGGLQNSADWLAGRGSWQIGDADFSAR
RGTVAI
>A0A1G9LW32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geoalkalibacter ferrihydriticus|TrEMBL
MTVYPSRSQRFLDLLQQRVLVGDGAMGTLLYQRGVALDANFEHLNLVRPQLVLEVHQDYA
AAGAEVLETNTFGANRLRLGAIGLAHKVAAINTAGARLARQVAGEERFVAGSVGPLPPAR
GEEQDLSETQKGEILREQMSALAEGGVDLFILETFSSLADLQLALGIAADLGLPASAQLA
FLEGGRTRDGVAAEAAVRALEQADAALIGANCGAGPRDLLTVLRQIAPLTQRPLAAYANS
GFPQYRDGRFIYLATPEYFAAMGREMALAGATLIGGCCGTTPDHIRALAQSLNQLTPAAR
PSAPARPHATQPSISPKPAAPHFLADWGRRPIITVELDPPRGLNCDKVLGAAEKLRAAGV
DAISLAENPLARIRMGNLALACRMQEQTGVPVIAHVTCRDRNLIGLHSEMMGAHLLGIRN
LLAVTGDPVSLGGEAGASSVFDLNSIGLLELLTALNEGINLFGTELEGRSEFLLGAAFNP
NVRHMDGQIRRLEKKIAAGARFVQTQPVYSHEILDKMLTLTDPLEIPVLVGILPLVSERN
AEFLHNEVPGISLPDEVRKRMRGLRGEEGIREGLAISGELVAAGRGRVGGWYLMPPFGKV
DLALALMKEIRRNAEH
>A0A7X7IEE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MQVIDILRQAKRPLFTFELVPPLKGGDVRTLLETVRQLSHFEPAYINVTNHQQEVVYLER
PDGLLERRTVRKRPGTIALSALIQYTFNIPVVAHLICGGMDRDQLEDALVELNFLGIENV
LALRGDPPNGEKRFVPVKGGYEHSSELVSQINDLNMGRYLDQGLQNAQKTHFCIGVAGYP
EKHAEAPNLARDIEMLKLKVDAGANYIVTQMFFDNAVYYRFVDACRKAGITVPIIPGLKP
IGSKRDLATIPQTFHVDFPSELVELLTKADKLSEIREIGVHWCTLQTKDLLAHGAPGVHF
YTLGKAESVASVVRSCY
>A0A1I6VB65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bohemicus|TrEMBL
MSQLSTCFTQNQFCVLVEYLCSMKEILPVKTQFAGFPALMTLADRVHADDDLAPIIAAQA
YPKYVEKVLHFAGKGRDISDFEQFLNDAQAIGQQNLLLLTGDKLKNHHKGKDSSERTRYL
ESVNAVMAAKQHGNFCVGVAFNPFKYAEAERDAQYLKLHKKLKAGADYIITQLGYDLSAL
KEAKAFLTQHGYAQKLLACVMPLTLARANFMVKHQVAGIVITPHMLKILSEEKESGLTDR
VYLRCALQILICKQLGFAGIHLSACHKPEEQLLLESYIEEYRHLGLDELELMWNALWQVK
TGKEFYPALTYYSRPVSSMQILKYQHLNLMHDAFFESKVAKGVGHFIFQSRFWNGSLAAQ
ALLKTEFVSKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVDQTQILKNNLIPTVPIEVRGSSSWKNWYVNQAS
>A0A8H9D041|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQIGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGARQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A1G8DYJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas flavescens|TrEMBL
MIQKKTNVSFEFFPTKTDAGHEKLLNTARELAGYNPDFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDSKAELIELLNLYKSKGINRIVALRGDLPSGMGLASGELRHAND
LVELIRQETGDHFHIEVAAYPEMHPQARNFEDDITNFVRKAKAGASSAITQYFFNADCYF
YFVERVRKLGVDIPVIPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDSASIQAF
GEQVITQLCERLLQGGAPGLHFYTLNQSAPSLAIWNNLQSRR
>A0A2S3ZXH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter glacialis|TrEMBL
MSPPSLIQASAPSTHSAPIALSYELFPPRNESASASLWDTIRELECTNPDYVSVTYGANG
SNRDTAVELLNRLLTETSLRPLAHLTCVGNTADELAEIISELLDHGVRGILALRGDLPQD
APSQPRAGSLSYAQDLIELIRRVEQRRSALLCAGKVAIGVAAYPAQHPESPSIEHDVEVL
LAKQRSGADFAITQVFFHADQYKDLVSRARRAGVSIPIIPGVMPLTSLRRVQRLGDLTGV
APSTKLLDALGRADDAAESRRIGVGATVDLARAALDAGAPGIHLYTFNEHAAALEVLDKL
QLLRPARPQPGLRGASSTIGTTARLVRA
>R7BKE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:882|TrEMBL
MKIRDILNQDKTTLSFEVFPPKKETDFANVETAAFGIAKLQPSYMSVTYGAGGSTKGHTI
KLAHEIQEKYNVPTIAHLTCVCADRAGINAALEEMKGAGIENILALRGDIPKNYEGEVFT
DFAHASELVELIKASGDFCVGGACYPEVHPDSANRNEDIIGLKRKVDAGCEYLTTQMFFD
NNIFFNFMYRIREAGITVPIIPGIMPITRKAQVRNAVKLSGCNVPERFKNIVDRFGDSED
AMKQAGIAYATDQIIDLIANGVRHIHVYSMNKPEIAEGIQRNLSEILKM
>A0A1M5NXM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marivita hallyeonensis|TrEMBL
MTTPSVSFEFFPPQSLEGSFRLWDTVQALAPLSPRFVSVTYGAGGTTRDLTREAVATLHK
SSGLPVAAHLTCVNATREETLKIAQDFATAGVTDIVALRGDPPKGTEGFTPHPDGFASSI
DLIEALSDTGHFTIRVGAYPDIHPEAKSADADVAYLKRKFDAGASEALTQFFFEAETFFR
FRDACEKAGIDKPITPGILPIENWKGAVRFAKRCGTHIPAWVVDAFEKAERDGREDLLAT
AICAELCSDLLDGGVDSLHFYTLNRPDLTRDVCHALGVTPKIELRNVA
>A0A0N1LL03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|alpha proteobacterium AAP38|TrEMBL
MDAAANPAPLITAPGDLTVSFEFFPPKTEKMHENLWTAIRRLAPLNPAFMSVTYGAGGST
RERTHATVTGIQAETGIPAAAHLTCVAATKEEIDEIARNYWDAGIRHIVALRGDPPPRAD
GTGGLGGRGYEPHPGGYAYAADLVAGLKRIGDFDISVACFPEVHPEAPSAQVDLDNLKRK
VDAGANRAISQFFFDVDAFLRFRDKAAASGIDVPMVPGILPILNFTKAAEMGEKCNTAIP
AWMRDLFDGLDEAPETRHLVAATVAIEQCRYLEKHGVKQFHFYTMNRADLTVAICHMLGV
RAAKG
>A0A1G7Y2E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium omnivorum|TrEMBL
MKVTQHIEAAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGSGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKIGGNDFAVDLVKQIDQLNCGKYLHEVMDVDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVYQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIKQIASKVF
>A0A212CQG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cervus elaphus hippelaphus|TrEMBL
MPSPSPPPPCSRNSAMVNEPRGNGGPGPRLEGSSSGSESSKDSSRCSTPGLDPERCERLR
EKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKE
TSSMVIASTAVNYCGLETILHMTCCHQSREEITGHLHKAKQLGLKNILALRGDPIGDQWE
EEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKGHPEAESFEADLKHLKEKVAAGADFII
TQLFFEADTFFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEP
IKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRP
LPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLF
YLKSKSPKEELLKMWGAELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSL
MKEELLRVNRRGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRP
PQDERETEAP
>A0A0Q8EUS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas sp. Root630|TrEMBL
MPIPVSFEFYPPKTDEQRTQLDRTADKLKAHAPEYVSCTFGAGGSTLSYTSETVRHLNQH
HGFDAAPHLSCVGGSREEIRELLRLYRALGCKRIVALRGDLPSGMGHPGDLRYASELIEF
IRTEHGDTFHIEVGAYPETHPQAEDALADLRHFKAKVDAGADGAITQYFYNPDAYFHFVD
AARKLGVEIPIIPGIMPISNFAQLRRFSEACGAEIPRWIGKRMQALGDDADAIRDFGADV
VTNLCERLVAGGAPSLHFYTLNLAKPTQTVLSRLGWTG
>A0A257KY02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobiaceae bacterium PARB1|TrEMBL
MEFEMTETTPATPNLPNISFEFFPPKTEEMDRTLWETIERLAPLSPSFVSVTYGAGGSTR
ERTHATIVRILKETNLTPAAHLTCVGAPRGEIDDVVARYHEAGVRHIVALRGDPATGIGT
QYAAHPDGYQTSADLVASIRNRYPEIDVTVSAYPEKHPESADFDADIDVLKAKVDAGATR
AITQVFFDNDLYFRYLDKVRARGIDIPVLPGIMPMHNFKQARNFVTRAGTTVPNWLADKF
DGLDDDAETRKLVAATVVAGQVQKLAKAGVNDFHFYTMNRADLVFAISHLLGFRPNSARK
AA
>A0A1F4TS90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-1 bacterium RIFOXYB2_FULL_48_7|TrEMBL
MKVTEAFKSGAPTLSFEFFPPKTPQQEEQLFEVIGQLKEFNPNFVSITYGALGTSRAKTF
QWAKIIKSDFGLEPIAHLTCVAASRPGIAAQLKELTELGIENLLALRGDPPQNDPGFRPP
ADGFRYASELISFIKQQYPAFCVGAAGFPEKHPSSPDLAADIRHLKIKVALGAEFVITQL
FFDNQDYFAFVDRCRQAGITVPIIPGVMPITGYKQIKKMTDIIGARIPAPLLEKIEKYQT
EPETIKQLGVEQAINQCRGLLERGVPGLHFFVMNQSGPIAHILTALDLKR
>A0A3A1XFA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium VN002|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNAAGVFNHASDL
VSYIRSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A2D6THB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium|TrEMBL
MTTNAPISFEFFPTKTEAGHEKLLATAQTLAAAGPEFFSVTYGAGGSTRDGTRRTVLQLD
GEVKVPTAPHLSCVGDSREDLRSLINDYRANGIQRIVALRGDLPSGMGHASGELRYANEL
VEFIRAETGDHFTIEVAAYPESHPQAPNFETDLQNFIRKARAGADSAITQYFFNADCYFH
FVDRVRQAGXDIPIIPGIMPITNYTXLARFSDAXGAEIPRWXRKXLEAYGDDSDSISAXG
TEVIXQLCXRLLXGGAPGLHFYTLNQAEPSLAVVRNLQGDR
>A0A1I6VTF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bohemicus|TrEMBL
MTKRIPVSFEFFPTKTDVGAEKLRVVHQELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYASDLVA
FIREHSGDHFHIEVAAYPEMHPQAESFDQDIQNFITKARAGANSALTQFFFNPDAYFYFV
DRLHKEGVDLPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNQTEPNRQLVLDLGLA
>A0A229GC83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NBS 14/10|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTEKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRAELRNVIGQYAGAGIRNMLALR
GDPPGDPMGEWVRHPDGVGYAAELVELIKESGDFCVGVAAFPEMHPRSADWDTDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAATGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPDLAERILAVKDDAAAVRSIGIDYATELCARLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>A0A1H9N5C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parafannyhessea umbonata|TrEMBL
MRIDSILRSKQSFSFEIFPPRGDLSVEQARSIANEMEKCRPDWISVTFSAGGSGNSQNTV
EIARDIQEAGKTTALAHLTCLGSTKADVDSIVDRLESHGVENILALRGDRAPGREASDFH
HASDLIAYLRQRGLCVGGACYPEGHVECESLKTDIENLKLKQDAGVDFLVTQLFFRNEDF
YRFREKCTRARIKVPIICGIMPFTSVNQIQRMAFNCGASIPAAVVKRLVRAGDSPEAQRV
AGVEYACEQLEDLARNGVDGIHVYSMNKPEIARAAHECLVAAGYLEA
>A0A519HPN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax sp|TrEMBL
MTASVSFEFFPPNTPVGVEKLKTVVQELGALSPQYFSVTYGAGGSTREKTLSAVMDIAGA
GFEAAPHLSCVGSTRENIAEILGTYREQNIRRVVALRGDLPSGTATAGEFRYAAELVSFI
RETQPEWHIEVAAYPEVHPQQRYANKDLQHFVDKMKAGADGAITQFFFNADAYFQFVDDV
RKLGVTQPIVPGIMPFHNYGRIAQFAQRDAIDIPRWVQMKMEGFMDDTASIRAFGLDVIT
KLCERLVAGGAPGIHFYTLNQSGLTLELCKRLKLGNHA
>A0A8H8XH12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bathymodiolus brooksi thiotrophic gill symbiont|TrEMBL
MKTSFEFFPPRTEKGKQNLAQVQQELSVIQPDYFSVTFGAGGTTQDATLETILNIQKNDL
VSAAPHLSCIGSEKKNIIGLLDQYKAVGINRIVALRGDIPSGVRDIGDFHYANELVEFIK
THYGEQFHIEVAAYPEMHPQAKNIHADLQHFANKVRTGADSAITQYFYNADAYFRFVDDI
EKLGINIPITPGIMPITNYTQLVRFSHMCGAEIPKWILERLKLYENDLDALSAFGTEVVT
NLCQTLKDQGVNNFHFYSMNRTQPSLDIAKTIL
>A0A822LRB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides vulgatus CAG:6|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A1C5XYI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MGNTKYTKEQIRERIQQKKILFDGAFGTYYGGKYDTRQLPELANLEAPERVKEIHREYLE
AGAQILRTNTFAANSFCMDIPREQIGETLRSGLRLAREAVAEWRDTTGETKEIYIAADIG
QIPGEAMAQKDALSREYEEICNIFLEEGADFFVFETFSEMEELLPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGEAKEIDAVGFNCGVGPSHMHRILQILEKPEGKLLTALP
NAGYPQMVTGRMLFTGDNKDYFVDRMQQMTALGVDMAGGCCGTTPEYIAELAGKLDLTQY
PQAKKDTEPEKQQAPKEDRSFYHTKEAEGRNRKLIAVELAPPMGIDDEKLMDAAHLLQKS
GVDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGI
QNFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFTQAPASYGGAINQGRRNL
EVEIGRVKKKMAAGATFFLTQPISTQESADRVRRIKEETGARILCGIMPFVSLKNATFMK
NEMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVIVMTEDFADGYYFSFPFNRVTMLE
KILN
>A0A6I6W235|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. S35|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQTEPSLAIWNNLKLPR
>A0A7X7Y5P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacilli bacterium|TrEMBL
MGLLEDLKDDILIADGAMGTILYSHGVDQCFEELNLSYPEQIKHVHEAYIHAGAKVIQTN
TYGANYIKLARYGLEEQVKKINQRAVQIAKEASRGRAYVLGNIGGIRGSRVLNETLSEIK
RSFREQLYSLLMEDIDGLILETYYDLEELKAVLTIAREETDLPIVTNVSMHEPGVLENGT
TLAEGLKQLEELGADIVGVNCRLGPAQIERALSTVPLPKRAYLAAYPNASLPAYRDGVLY
YENEPSYFKTAAEHLRQQGARLIGGCCGTTPEHIRAMAEALKGKKPITEKVVPIQERIKA
VKEPERKEKTIPELAKEKTTIIVELDAPKHLDLTDYLKGARALKEAGVDAITLADNSLAT
PRISNMAVATLLQKEGIRPLVHLTCRDRNLIGLQSHLMGLHTLGIHEILAITGDPTKIGD
FPGATSVFDVNSFKLIELIKKGNKGISFSGQSLREKTAFSVAAAFNPNVANLKKAVQRME
RKIESGADYILTQPIYSAEKFKALKEATRHIDVPIFVGIMPLTSSRNAEFLHHEVPGISI
ADEVRDRLKKVADNREKSTEESIKISKELIDAALEHFNTLYLITPFMRYDIIVELVKYIH
EKTSEKADQAII
>A0A0H3H1B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella oxytoca (strain ATCC 8724 / DSM 4798 / JCM 20051 / NBRC 3318 / NRRL B-199 / KCTC 1686 / BUCSAV 143 / CCM 1901)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAKDYWDSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFRQAKKFADMTNVRIPTWMAKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1X1Q0K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia casuarinae (strain DSM 45818 / CECT 9043 / CcI3)|TrEMBL
MAAVRSLSTQPTTMGEYLATGRASFSFEFFPPKTPDGERQLWTALRQIEALHPSFVSVTY
GAGGSTREGTIRVTERIATDTTLTPIAHLTAVNHSVAELRRVIGNYAGVGVRNVLALRGD
PPGDPQGTWTAHPAGLRHADELVRLVRSVGGFCVGVAAFPDKHPRSVDFDSDARYLVSKF
DAGADYAITQFFFGADDYFRLVDRVRRLGCDKPIIPGIMPVTNVAQIVRMAQLSGAAFPP
ALASRLQAVADDPAAVRAIGVEVATELSRRLLDGGAPGLHFITLNRSSATREIYQAVR
>A0A652LX19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. or43|TrEMBL
MALGTPSTRTDHARTVREMLETGKTSYSFEFWAPKTEKGERNLWNALRRVEAVGPSFVSV
TYGAGGSTRAGTVKATQDIAAESTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGPWVEHPQGVRYAADLVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCETPIIPEVMPLTSVRQLERFAQLSNAML
PADLKERILAAKDDPAAVRSIGIDFATRFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A117QFK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces corchorusii|TrEMBL
MALGTASTRTDRARTVSDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAVAGCETPVIPEVLPVTSVKMLERLPKLSNAHV
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A1C5QFP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKIRDILNKDTATLSFEVFPPKKSTDFGNVEAAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAREIQKQYNVPTVAHLTCVCADRSSIGAALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKENGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIVPGIMPITRGVQVRNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNLSEILKA
>C9RB79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ammonifex degensii (strain DSM 10501 / KC4)|TrEMBL
MRSGSRLERLLARGEFVVTAEIGPPKHASAEPLIRKARMLKGYVDAANITDCQTAVVRMA
SIPAAVHLLREGIEPVIQMTCRDRNRIAIQADLLGAYSLGIRNLLCLTGDHPAVGDHPEA
KGVFDLDAIQLLDMVRRLRDEKVFQSGVPLKGPEPRFFLGAAENPCGDPVELRVMRLAKK
VEAGADFIQTQCVFDLECFSRWMELVRKDGLDRRVYILAGVTPLKSARMANYMHENVPGI
SIPEEIRERMAKAADPHEEGIAIAVETIQALKKIPGVAGVHIMAIAWEEVVPEIVKRAGL
FPRPQLPEDSDK
>A0A093ZTH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-3808|TrEMBL
MADSATTDKITDKIAALPQDASYFSLEFFPPKTAMGSTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSRALVDDALMAAKEAGIQNILALRGD
EPRGEYKDALEAGKEGEDEFVWAIDLVKYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
EHDLPYLVDKVKAGADFIMTQLFYDVDAYDKFEQILRDHSSGAFKTIPIIPGLMPIQSYQ
ILRRTTKLSNAKLPQSIIDRLDAVRTDDEMVKKVGVDIVAEIVESVRHTKSRTKGPKGFH
FYTLNLEKAVAFILERVNLIPSFTPVLTSDVFVDDITDTIPLPQLLINGERKSRRQSSVG
SGPHNFVIIDREEASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNGR
WGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRSDISSIFVQYLNGTLSALPWSDEP
ITAESGLIKDELVKLNQKGWWTIASQPAVNAARSQDEVVGWGPKGGWVFQKAFVELFVPT
SDWARLKTLLEGNAEVSFLAQSASGEFLKSKLELGPGEEGSETNAVTWGVFPGKEIVSPT
IVEEVSFRAWAEEAWQMWREWAAVFGKGGDESRRFLDGVAKDGWLVNVIWHDFVGMCKAK
EGRSEEEGYKGLWDVLIEA
>H9UL29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaeta africana (strain ATCC 700263 / DSM 8902 / Z-7692)|TrEMBL
MNHLYTSLQQRESGLLVYGLTPPKVDNPVEKNRRITERRISRISQSPLDGVVVYDIQDED
TRTDAERPFPFLETIPSYTYADHDLHGLELPKIVYLSVGKYTPEELDTILGNLQERIVVF
VGSPSPEFPARTSLRQAYEMYQKYRSRLVLGGVTIAERHRKHHNEHQKLLRKSAAGVSFF
VSQCIFNAELFKDLLSDYYHICEDEGLPMQPVLMTLTPCGSLKTLEFIKWLGIQVPRWME
NDIKRNRDILHYSMRMAREIFQNISDFCSDKGIPVGCNIESVAVNREEVLASFELARQIR
DLQQR
>A0A1C6KWF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKIKDILAAGSPTLSFEVFPPKGEEAYESVEKAALEIAKLKPAFMSVTYGAGGGTSRYTV
GIASDIQRETGVNTLAHLTCVSSTRSEVKSVLKQLREKQIENVLALRGDIPADGPIATDY
RYASELIYDIKQFDENLCIGAACYPEGHVESVNKTADIEHLRDKVEAGCDFVTTQMFFDN
NILYNYLYRIRERGITVPVVAGIMPVTNVKQIKRICQMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAKIGDSLSEIL
>Q2JAL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia casuarinae (strain DSM 45818 / CECT 9043 / CcI3)|TrEMBL
MRGFEMICEIEPPTRPDLTHARHQIGVLSPVTDAFLIPDNHIGRATVSSIAVAHEVATMG
GRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVHGDKPTAGNRTGDLTVRAMMDEARA
ASEDPVFADMPAFRVGAAAGLRPLPTWKRAADFLFVQISYSVDALLRWRDAHPVELPIYA
GVMVLASAGMARRLAAAIPDIDIPDNLVQAVERDQAAGVEAACDQVLRLRDSGAFAGVHL
VPVSRYRQVATRLEDLL
>A0A1S6JE24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces pactum|TrEMBL
MALGTASTRTDRARTVRDMLASGKTTYSFEFSAPKTAKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPTADWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILTANDDPTAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A260Q4B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 02-925g|TrEMBL
MSEDSVRGRSSRGFVTRTPSIVDRLRTEPEARIPFSVEFSPPRDAAAEARLWRAVREFEQ
LQPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRG
ITNILVLRGDPPGDPLGDWEKHPDGVEYAEELVRLVRDLGDFHVGVASFPEGHHRAGDLE
QDTRCLVGKLRAGAEYSITQMFFDVDDYLRLRDRVSAFDAEQGAKPIIPEIMPITSLRSV
RRMLELSGTTLPSHLDKKFTRAAGSGPEEDRAAVREVGIELATNIGERLISEGAPGLHFI
TLNFARATREVLSNLGLAAARV
>A0A6J6D0E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MNKQVRVSFEVYPPRDQNSGESLESSIIELAKMDPTFISVTFGAGGSSTKNSLEVLKYIL
QNTQAAALAHLTCVGHSFLETKALVNQFMDEGISDFLALRGDPQPGMPVEPKGELKTSSE
LVQLISQVHKDRGNSRSTLNVAVATFPNGHPDSDSIAQDIQALLAKQNAGADYAITQLFF
FASDYVAFVKLAREAGVTIPILPGIMPVTSMQRLNRVIELTGEKYPEALAKQLSVTSKEE
AKQAGIDWAANLVSELVEQGAPGVHLYAFNQHESVTQVLQRAGIR
>A0A6J7PH40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVVRTSYSLEFFPPKDGEGETRLWDALENLQSINPTFVSVTYGAGGSTRNRTIGVTEEVT
HRTKIPTVAHLTCVGSSRQELISILHMYKAAGIKGILALRGDPVGGPRAPWTPTSDGFTH
ADELVQLIHEFGGFDIGVAAFPDGHPGSDGDSKKDIDVLLRKEFLGAQFATTQFFFEVSQ
YVKLVDALQARGSTMPIIPGILPITNVKQLQRMAELGGTPIPPQVAKSFGAVEHDPRAVH
QLGIELASQLCEDLLSAGAPSLHFYTMNSPTATLEIYGNLNSAD
>A0A2T0LEC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planifilum fimeticola|TrEMBL
MGEKRCLKEHLRENLIVGDGAMATYLYQQGVPVGLCYEELCLTRPDLILEVHRAYFEAGA
RLLETNTYGANRERLTRYGLEGKVTRINRAAVRLAREAAGNEAFVAGAIGSVLAGRVPRY
DRDEYRDMYEEQATALLHAGADAILLETFLDLEELLLAVEVIRPLTEVPLIAQLALLEVG
RTRDGYPLTEAFRRLQEAGVDGVGLNCRLGPAECLRSLEQAAVPEDVYLSAFPNAGRLGI
TDGEYRYKSSPEYFRESALRLREQGVRLIGGCCGTTPQHIRAMAEALRGLSPLPRINPEG
ASLERDSVPLAVQPPRKEPAITEKVEAERTVIVEYDPPRDLDIARFLHGATRLKEAGADV
ITLADNSMATARMSNMALGAILKSRGIEPLVHVTCRDRNLIGQQSHLMGLWALGIDQVLV
VTGDPTRIGDLPGSSSVYDVSSFDLIRMVKQLNEGISFSGKPLKQRARFVVGAAFNPHVH
NLEAAVRRLEKKVEAGADFVMTQPVYDPETIGRIHEATRHVGIPVFIGIMPLTGFRNALF
LHNEVPGIKIAPEVMERMRRCRGKEESRREGVAIARELVDAALEHFRGIYLITPFFHWRM
TAELTRHIRERDRRHAVVGE
>A0A1V2ZVW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioalkalivibrio halophilus|TrEMBL
MSNQERVFSVEFFPPKDEAGAERLAKARKRLGALKPEFYSVTFGAGGSTRDRTLETVKDI
INNDGIPAAPHVSCISSTKDELRDLLNAYRDIGVDRIVALRGDLPSGTRHSGGDFRYASE
LVEFVRAEFGNQFKIEVAAYPEFHPQAPSAEKDLDNFKTKVDAGADTAITQYFYNVDAYV
AFMERVQAMGITIPIIPGIMPITNYTQIVRFSEMCGAEIPRYIRKRMEAYGDDKDSIRKF
GIEQATRLTDDLLEKGAPGIHFYSMNQAGPTEQIWKDLDLDSRR
>A0A6J6DRT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVLGTSYSFEFFPPKDVEGEERLWHAIEGLKSISPDFVSVTYGAGGSTRDRSIRIAREIT
DRTGISTVAHITCVGSTRAELLEILHSYKDAKITSILALRGDPVGGPLAPWIPTEDGLTH
ADELVELARDCGGFKIGVAAFPDGHPSSGGNFEKDIDVLIRKEQLGATFATTQFFFDVKA
YANLVERLAKRGSSLTIIPGILPVTNVKLLHRMAELGGTPIPSHIAKSFADVESDSQAVR
NVGVEIATKLCQELLEVGAPGLHFYTMNSSTATIEIYRRITDAQ
>A0A1A9PVP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPFHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGILISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6J6B4Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MERMTVSVEFFPPKDDAGEARLWEASTALESISPDFISVTYGAGGSTRDRTVQITKEITK
RTGRSTVAHLTCVGSTKDELIEILGQYKSAGIKSILALRGDPVGGPAAKWVSKPGGFDHA
DQLVELAMGQGGFEVGVAAFPDGHPASDGNLTKDIDVLLSKEQLGATFATTQFFFESSKW
ETLVSELAKRGSALPIIAGILPITNVKQLQRMAELGGTAIPVQVSKLFNEIADDPEAVKR
AGIELATNLCNELIDLKVPGLHFYTMNSSPATLEICTNLGLTNRE
>A0A6J7ART1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSPTRTAPSLGAVLAGGGHSFSFELFPPKTDAGEQALWQTVRELEALKPTFVSVTYGAGG
STQDRTVRITKQIAEHTTLLPVAHLTCVDASVDDLRKVIAQYSDAGVNTIMALRGDPTAG
PESQWVQHPGGLRHADELVALVRELGAFSVGVAAFPEGHPESGDFEDDARVLAAKQDAGA
EFAITQFFFRAEDYERLVTRAAAHGCTMPIVPGLMPVTNVAQIERFAVLSGAQFPSDLAD
KFGKIKDNQSAVHELGVEVAADLGAKLLAMGAPGLHFYTLNRSTSTREVYEALGLNQV
>A0A6J7P0Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MREEGAGAGSDASRRSLGEVLSTGSRSFSFELFPPKTDDGERALWQTIRDLQGLSPSLIS
VTYGAGGSTRDRTVRIVGGIAAEPALTPLAHLTCVGASRDEVRAVVDEFAAAGVRAILAL
RGDPPGGPGSAWVQHQDGFAHADELVEFIASMGNFSIGVAAFPEGHPESANLADDAVVLA
RKQDAGAEFAITQFFFDARDYERLVRDAAGHGCTMPILPGLLPVTNVAQIERFAALSGAA
FPADLAARFALVKDDPDAVHSLGVEVAAELGQKLLEMGAPGLHFYTLNRSASTLEVCEAL
GLGAR
>A0A6J6MXB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSDYRLLRQANQADGTAASVIEALQTRASLNQQTLSFEFFPPKDDEAAAALWKHYETLIE
AEPDFVSVTYGAGGSSRETSLAVVDRMAKDVLTVGHLTCVGATAESSRETIKHFEQAGVS
SILALRGDPPLNDPQVLAVGEMKTALDLVQLAKSVSSLEIGVAAFPEVHPESPSMQHDAE
VLRLKQDAGATFAMTQLFFSVEAYLRLVSAAESAGSVMPIVPGLMPISNAAKVLRMAQMS
GADVPRELLEKLENASESDARVIGMDYSVRLANDLLQAGAPGLHIFTLNYSKAALEVARG
CGLA
>A0A6J7JFY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MCGMRIDEIIETSADPTFSFEFFPPKTDEAEALLHDALETLRELSPSFVSVTYGAGGSSR
DRTIKVVRNLRVEHGLEAMAHLTCVGATKDEIRTVLGQMRDAGIDNVLALRGDPPGGEEK
FSPTPGGFASSPELTALVDEEFPFCVGGAAYPEPHPDARHDDDDVQTAKAKVEAGAKFLV
TQIFYDNSDYFSFVGRLRDEGIDVPVIPGLMPITSIGQSRGFLKKIGARIPEGYRAELDA
REDDPDAIKSLGISYATLQAAELLAQGAPGIHFITMNRSPATRAILATLRLHRPWERTPE
SPASTGGQPSLA
>A0A6J6UGD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVVRTSYSLEFFPPKDGEGEARLWDALENLQSINPTFVSVTYGAGGSTRNRTIGVTEEVT
HRTKIPTVAHLTCVGSSRQELISILHMYKAAGIKGILALRGDPVGGPRAPWTPTSDGFTH
ADELVQLIHEFGGFDIGVAAFPDGHPGSDGDSKKDIDVLLRKEFLGAQFATTQFFFEVSQ
YVKLVDALQARGSTMPIIPGILPITNVKQLQRMAELGGTPIPPQVAKSFGAVEHDPRAVH
QLGIELASQLCEDLLSAGAPSLHFYTMNSPTATLEIYGNLNSAD
>A0A0S4I6Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. URMO17WK12:I11|TrEMBL
MPACQHPVSVMSVLKTALQEQQFACVMEFVPKPSAERFAAMDAIMARGQVCGWPMTLAIG
DRVSSPLDMSPLDALACFEHPVPALPHFSGKDRERHHLLAQMRRMDAAGQHQLLMLTGDR
LPGHTPGERPVRYLESVAALQIARQAYPHWWLGAALNPFKYREEEGAAQYLKAEKKLAAG
ADFFILQLGFDAAKHQEAMHWMRRQRAPKPLLACLMSLTQGRAGMLDHVAGVTVTPSMRQ
MLEAETAQSKAFAQARSIDRLALQVIGVKLMGYAGVHLSGIHEPSQLLALEARLEHWQAH
VTTLEQWAPAWQASWQMPGLPAVTFHPPQAAWREGESRVVATFAQKARYHAMHGMHGLLF
SRSNPVSQLFGWAVRQPMWTTGLGAQVLHSLERAVKRPLLGCDTCGRCRLEDTLYTCPET
CPKGLANGPCGGTTLNRCEFGDRECIHSAKYRTAKAVRQTDVLAQRLIPCVEQHTRHRSS
WPGWFGAQAQPVTRPSAPRSRPES
>A0A6J7DTV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRIDQLLAAGATRSFEFFPPKNDAESAILADTIRDLRSLDPSFVSVTYRGGRESRQRTFD
LVHSIETEGHITAMAHLICVGHGRDEMRDILQNYVDGGVENIMALGGDIPVDPALQGGEF
THALELVELAREVGSFSIGVAAHPLGHPRSDDLVSDRKHLATKLREADFAVTQFFFDFEE
WRRLVNELGSLGVTKPVLPGIMPVTTLSGVTRMADMGAAVPIWLVERLERAHEQGGSPAV
RTEGIRAATELCRELLDGGAPGLHFYTLNRSTATQEIHSQLFG
>A0A6J6U401|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRDAAGHGCTMPILPGLLPVTNVAQIERFAALSGAAFPADLAARFALVKDDPDAVHSLGV
EVAAELGQKLLEMGAPGLHFYTLNRSASTLEVCEALGLGAR
>A0A653I2J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnobacter sp. 130|TrEMBL
MNKHTMMNISFEFFPAKTDEGAEKLRATREKLSERKPEFFSVTFGAGGTTQDGTLSTVLE
IKASGEEAAPHLSCVGSSKEKVAALLKQYKENGIKRIVALRGDLPSGMLETGSFRYASEL
VEFIRQETGDHFFIEVAAYPETHPQAKSPAADVDAFVHKVNCGANSAITQYFFNVDAFLY
FRDQVQHRVSIPLIPGIMPITNFSQLARFSDACGAEIPRWMRTRLQHFGDDRESIRAFGL
EVVSNLCEQLIKEGAPGLHFYTMNNAQPTLSVLDQIGY
>A0A2K0U516|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma harzianum|TrEMBL
MHIKSLVAETEKSKAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLEKVNDALQKAYKAGCTNILALRGDPPRDQES
WTAADGNFQYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGAGF
IVTQMFYDADNFIRWVGKCRVPPDWMAKLEPVKNDDVAVREIGKTLVAELCKKLLANGIH
HLHFYTMNLAQATRMVLDELNWTPSAENPLKQALPWKQSKGFGRRDEDVRPIFWRNRNKS
YVIRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLTGTNEQNRKKWGEPASIQDIANTFVQ
YLEKKLETLPWSESGLAAEADPIKDDLVALNKRGLLTINSQPAVDGAKSNHPVHGWGPLN
GYVYQKAYLELLMPPYLLEEMISRLDDFPNLTYYAVTKNGELRSNAPSDGPNAVTWGVFP
GKEIVQPTIVESVSFLAWRDEAFRLGVDWAHCFDANTPSRALIEGIMNEWYLVNIVNNDF
RENSTIFGFLEGLEVKDLAVPVTGTA
>A0A2T3AJG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coniella lustricola|TrEMBL
MHVKEMVAEAERTGKPSFSFEYFPPKTLTGVQNLYDRIERMDHFGPKFIDITWGAGGRVA
ELTCEMVNQAQAYFGLETCMHLTCTDMGLERVDDALRRAYKAGCTNILALRGDPPRDKEK
WEAADDGFTYAKDLVAHIRKTYHDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDAGAGF
IVTQMFYDVDNFLRWVRKVRARGIDIPILPGIMPIATYASFLRRANHMNCRVPDEFMAAL
EPVKNDDVAVRDVGKSLVAEMCRKIVSAGIPHLHFYTMNLAQATRMVLEELDWMPTEQTP
IRQSLPWKQSLALGRRQEDVRPIFWRNRNKSYISRTMDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSIRDVSNVFLKYLNQELDSLPWSEAPLTGEASPITHDLIE
LNKRGLITINSQPAVNGVKSDHPVHGWGPRNGFVYQKAYVELFVSPDVFPELISRIEKNP
DLTYYATTKSGEFKTNTPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGMDW
ARCFDAGSPSRILLERMMREWHLVNIVNNDFHQPRTIFEITSDLQVQDIDVEVQSDGPVS
AK
>A0A117IX22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces kanasensis|TrEMBL
MALGTPSTRTDRARTVRDLLAGGTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVT
YGAGGSTRAGTVKATQEIAADTTLTPVAHLTAVGHSVAELRNMVGQFADAGIRNILALRG
DPPGDPMGEWVPHPEGLDYAADLVRLIREAGDFCVGVAAFPEMHPRSTDWDTDVRHFVDK
CRAGADYAITQMFFDPEAYLRLRDRVAAAGCDTPIIPEVMPVTAVRQLARLPQLSNAHFP
PAVEERILAVKDDAAAVRSLGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HPQS
>N9PVP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 102136|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAADLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A2A9GY46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriaceae bacterium ES.041|TrEMBL
MTESSTRVPGPAAAPAPVTLSQLARNVSFEVMPFAKTEGLVLEHVPTEVPLSITVTEAKG
LEPTLALTERLTQQGYRATPHLAARLFTGDQQVAEVADRLTEAGVTSIFVIGGDAPEPAG
EFTDARGLLDSLERQGRWFETVSIGGYPEGHAKIDDATLSEALRTKAPHANGLITQACFD
AKVLGAWAADVARDGISLPIKVGLPGPVNRQKLIRISAGLGLGQSARFLAKQQNMVWRFL
LPGAYDPMKLVKKLGAVTARTPTHISGLHLFTFNEVAGAERWRQRLLTATREGH
>A0A2D7AH33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiloniella sp|TrEMBL
MTDTKAAVMKLFGDFTVETTPNSAAKIPDYNARLRNDTPIYVTFLPGSDVYETVTLAKRL
RSEGFSPIPHIAARSIQSEDMLRDILDRYVGEAGVEHVLTIAGGVDNPLGPFDSSMAVLE
SGLIDKAGIHRISVAGHPEGSPDITDELIKDALAWKNGFAERTGAALDIVTQFAFEAEPI
IAWDRRINAEGNRLPIRIGLPGLATIKTLLGFSRAAGVGNSIKFLVKRAADVTKLMNINA
PDKQVIELARYATEEPTAGICGVHMYAIGGLKRTSAWSYALKDGLFEVTGKDQLKVSVDL
G
>A0A1W9M8H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium A2|TrEMBL
MSLSFRESLTRPGQFTITYELVPGQGAGSRQVERLLAFTLRAQADGRIKALSITDNAGGH
PALAPSSIGADVQSLGLEPLVHFSLKDKNRNQIESHIFFYHRQGFHSLLVMGGDYPGRGY
HGQAKPVFDMDSVQTLQLFRDLEQGRYRSGSGIQQELQALSFFRGCVVSPFKIGQAEQVW
QYGKLLRKIRAGAQFIVTQLGYDLRKFDELLQFLRQTDRDIPVLANVFIPTLPVARLMSR
GQVPGIVFPPVLLRAMEDEAQSGRADEHRLRRAALMIASLKNMGYAGVHLGGNGLDFDKV
AQVMDMAEAMDGDWRELAREAHFPLPGTFYLYEDDASGGNGPRPRPLRSTRGPGAAWHFN
HALHTLLFTEDTPLGRGFGRLCRHAFGRPRLTRLLILLELCSKVPLFGCRLCGDCTLSES
AYLCPQSDCPKKLLNGPCGGSREGRCEVHPERPCIWVRVYERARCPADATALGQSPSLPP
KDWSLERGSSWINFFTKRDHRQD
>A0A8F8CW62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter septicus|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKIVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTAVAPHLSCIGDDKSRIAKLLDLYQSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAETFDADIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERLEKEGITIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A431W036|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus yapensis|TrEMBL
MSFLDRLKNEILIADGAMGTLLYSYGTDSCFEELNVSHPNDILKIHEAYIAAGSDIIQTN
TYAANYLKLQRYGLEESVKEINSAAVKIAKQAANNKAYIVGTMGGNRGVNPKAISIDEIK
RSFREQLYCLLLEGVDGILLETFYDLEEIETVLAIARKETALPIIAQVSIHEPGIMQNQT
PINEAFERLEALGADIVGLNCRLGPHHMIKSLEEAQIPNQAFLSAFPNASLPTYTDGKFH
YEGEADYFKKSAQAFREQGVRLLGGCCGTTPALIRSFAEELKGAKPVTEKIVKFKRVSSI
SIEHAPIKRNNTPLQTIASERPSVIVELDPPRKLNTTRFFEGAKALKEAGIDAITLADNS
LASPRIENSALAYLTKTQVGLRPLVHITCRDRNMIGLQSHLMGLHTLGLNDVLAVTGDPA
RVGDFPGASSVYDVSSFELIQMIKQFNEGLSISGKDLGQKGDFSIAAAFNPNVRSVEKAV
QRLEKKIKYGADYFITQPVYSEEKLIEVHEATKHLDTPIYIGLMPLTSSKNAEFLHNEVP
GIKISDSIRNTMAELQDDPIQSAREGIAITKSLIDAASELFNGIYLITPFLRYELTVELA
QYANEYSSILGRKQNV
>A0A182WJ84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles minimus|TrEMBL
MSTVSQSTMAAPVTDNGVLYTKLDRIFRSPTETSVRVSYSMEIAAKDDFDVGEVERLIPQ
PVFCALPWISDENLRYADDFRRAPTLALTDKLCKAQYTVVNHVSCYNITEQQVDGLLSSG
IQNLFVIRGDTVHEEQKFQHSAALVQYLRKQRKGHPKLTIGVGGYPYGHHQSPSKEEELR
YLKEKIDHDVDFLLTQTLYDAESFFRYREQCRTAGISIPVIPGIYVPYSYRHLRAMLNLT
RITLSPDMDAKFKAHATDDPEQFEAFVVDHFVGVLRELLEPNVTSSDPIRLVHFFSFNKF
ALLQKVLQKLNDFFQ
>A0A1I2B479|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. DSM 26671|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYREHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDRESIRK
FGEEVVTEMCEKLLAAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A2M8CAY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium CG_4_9_14_3_um_filter_33_16|TrEMBL
MIHHIQNKIYHIEVLPPKQDSEKLEKDLEIFSNKYLRVMDSSYCTCITDNTMGLLSFQGT
EIIEELDLPVMSEQVMIHLNTFHTKDDLDNILDICKSKGIRYLLIITGDGSERLPKLQPS
DVGATDVESVTSVELLKYINHEYPDTFVLGAAFNPYEPEEHEFEKMKRKMKAGATYIITQ
PLIERNEVVDRLLEKYPEIPVIIGTWMSRKLHLLSEAVGYEIPGNAEYDPISTLKMLHKL
YPGCGVYLSLLGFKTQYDLIKDIWV
>A0A437JWE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax albus|TrEMBL
MSTVNLPVPVSFEFFPPNTPVGSDKLKTVVAELAAVRPEFFSVTYGAGGSTRDKTLATVK
DIAAMGHEAAPHLSCVGSTREGLAEILATYRAQGIRRLVALRGDLPSGVALPGEFRYAAE
LVAFVRETQGPDWHIEVAAYPEYHPQQRYAKKDLEHFVAKVKAGASGAITQFFFNADAYF
HFVDAVRAMGVDVPIVPGIMPIHNYARIAQFAARDGIEIPRWTALKMEGFLDDATSVRAF
GLDVVTQLCRRLVDGGAPSLHFYTLNQSALSLEICRRLAG
>A0A2E9IF99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MYFYDEPIPGAPLPILPGHVSNGRFERVLRAGXFAVTTELAPPDSVDRNEVYRRARVFDG
YVDAXNVTDGSGANCHMSSLAVSALLTRVGYSPILQVSCRDRNRIAIQGDLLGGATLGVS
NVLCLTGDGVDAGDHPEAKPVFDLDSVSLLGTVKIMRERSSFLSGRQLDSAPRFFIGASA
NPFVPPYDYRPLXLKKKIDAGAEFIQXQYCFDIDRLVTYMNQVRDLGLDKRCFILVGVGP
LASARSAGWIRDHVPGVVIPDAIVSRLLSAKDQRREGIKICIEMIQQIREIEGVAGVHVM
AYRQEESVAEIIKTSGVLEDRVPWHPQCDQLAAGPWLAEEENECN
>A0A2E6P509|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MNTSRNPDLKNAVNTLLDNWTIEVTPGGAKKIDDFRNYLRLGTTVYITFLPGSDFADTLE
IALRLKEEGMKPVPHLAARSIPSSSWLKDNLDQLKTKVGLDQVLLIGGGVDNPVGDFSDT
MQLLDTGLFEEFEIPNIGIAGHPEGSPDISDENIKSALLWKNDYAKRTGFNLCITTQFVF
EAGPVIEWEKRVREEGNTLPIRIGIPGIATIKTLLNHARACGVGPSIRFLTRQAKNVAKL
VQPSSPDILLLNLARHQIDNESLINGIHVYPLGGLKKSAAWFATVGDEKYELNDEGDQMI
FSANDE
>A0A527UZ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGEKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A367V510|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira lucentensis MCCC 1A00383 = DSM 14000|TrEMBL
MTAQNNTAAKNDLRVSFEFFPPKTEKMEETMWRSIHRLAPLSPSFVSVTYGAGGTTRDRT
HSSVTRIQGETGIPAAAHLTCVGHTKQEIEQIARKYWDEGIRSIVALRGDLPDAGDTYVP
TPGGYDYAADLVAGLKEIADFDISVSAYPEMHPDAPSADFEIDYLKRKLDAGANRAITQF
FFDNETYLRFRDKCQAAGITAPIVPGILPVTNFGSLLRFAKMCGADVPKRFHWRFDGLDD
DPDTRRMVAFHEAISQVEGLMKEGVTDFHFYTLNRAELTYAICHALGIRGTEQAVA
>A0A1H9UL81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium cystitidis DSM 20524|TrEMBL
MSAKNSSSRPSARLSASAPLDGFDDTIQSMPSGVPGTAFRTRRPRRLALSFEVIPPRHDA
DEAKIDNLLATLNAYKPDYISVTSSARSQWLTGTTKFIKRISANTQARTIAHLACTAGTR
DELTEWIYTLLDSGVRGFLALRGDLPEGVSKLDGDHLPHATDLVRLIREIEQQEAFRLAA
GNLAVSVACYPSGHAESASPDEDLDVLLAKQRLGADFAITQLFFEAEDFLRFEQRARLAG
VRIPLIPGIMPMTSLKRAERMGVLSGISVPDRVYQRMRQASNEAEEFEIGMEMTVDLART
ILEAGTGGLHIYTHNNAEVTQDLLNRIGIPTPDALR
>A0A527E5T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQLDENPAGIDLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIASGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLEHILHDDVTETQVDMVK
TAH
>K5YAM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Chol1|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLAGYHPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVRVPTAPHLSCVGDSKAELRELLDIYRKAGIRRIVALRGDLPSGMGLASGELRHANEL
VEFIRSETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKAQAGADSAITQYFFNADCYFY
FVERVRKLGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIDSIQAFG
EQVISEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLPRQA
>A0A442MTL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFAGMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>D8F8N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|delta proteobacterium NaphS2|TrEMBL
MPLKEKIAAGKFIILGEFEPPKGADFDSFITDANLVKGRVEALVVPEMANAVLKASSLGG
CACLEREGIPSVFQVCCRDRNRLALQADILSAAALGVQNIMAVNGVETRFGDHPQTRTVN
DLDLIELIETVQTLSQGKDLAGVELKGTPGFSVGSTIDAGAAGNLLDIEMERLEKMLENG
VDYVITNPVFDLRRFEQFVKRVDTSKIAVLPTVLLLKSAGMARYIDRNMRGITIPPDTIR
RIQKAPDKVQECIRIAAETIKQVKKMGLAGVLISTVGWESKLPSVLNEAQL
>A0A150XWJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivirga seohaensis|TrEMBL
MKVTQHIKRAKGKTLFSFEILPPRKGENVNGIFDAIDPLMEFNPPFIDVTYHREEYIYKQ
HDNGLLEKVTTRKRPGTVGICAAIMNKYGVDAVPHIICGGFNKEETENALIDLDFLGIDN
VLVLRGDAIKSEGRFVPDPDGHSYATELMQQVLDLNQGKYLHEEVEMAKTNFSIGVAGYP
EKHFEAPSLKSDMKYLKQKVDMGAEYIVTQMFFDNQKYFDFVEKCRKADIHVPIIPGLKP
LTTLNHSTILPSIFHVDLPDDLVDELDKCKDNKAAREVGIEWCIQQSKELMEAKVPCLHY
YTMSKSSVIKQIAEKLF
>A0A1Q4R766|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnothrix rosea IAM M-220|TrEMBL
MTTRLRRAIENREFVITAEVAPPKGGNPAQMLAMARLLKDKVHGVNVTDGSRAVMRMASI
AASTLLLQNGVEPIFQMACRDRNVIGLQADLMGAHALGLRNVLALTGDPVKAGDHKKAKA
VFDLESVRLLKLITKLNDGQDFNGKKLPDGELDLFAGGAVDPQLKSWYTIESRFAKKVES
GAKFFQSQMITDFVRFEEFMERVAAQHNVPVLAGIFLLKSAKNARFINRCVPGAQIPDGI
IERLDHAENPLEEGIKIAAEQVKIAKNLCQGVHLMAVKREDLIPKVLELAETSITVKSEP
VLI
>A0A2D8KYK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MSRFAQALSMSEFVVTSELIPPKGVDLEPLFEKAEALNQVVTAFNLTESHTAKMSMDPVA
VGHLLLDRGVEPIVQMTSRDKNRIAIQASILGAAALGISNIVIMGGDSPKNGDHPEAKGV
FDLYSSQMLDAASALNGGADYMGNPLKGAPAMNIGAVVNPGASDPGAEIENLHRKIEAGA
GFFQSQAVYDVDALASFLHKADTDAVILAGIIPIKSVRMARFMNDKVPGINIPEALIAEI
EAAGDNPDRLVETSIDIAARIIRQIRPLVKGVHIMAIGWEDKIPAIIQRAMD
>A0A2T3CPI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. BBP2017|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKEDLRSLLTLYKAAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHVEIAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVNSIQKFG
EEVITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A3N2ERZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium nakagawai|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVDQINNLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A251UHS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helianthus annuus|TrEMBL
MKVIDKILESTTAGDAGKVVFSFEFFPPKTEEGVENLFERMERMVAHNPTFCDITWGAGG
STAELTLEIARRMQNLVCVETMMHLTCTNMPVEKIDHALESIKKDGIQNVLALRGDPPRG
QDKFVQIQGGFACALDLVEHIRRSYGDYFGIAVAGYPEAHPEVIESNGLATPEAYAKDLA
YLKRKVDAGADVIVTQLFYDVDNFLKFVNDCRQIGITCPIVPGIMPINNYNGFIRMTGFC
KTKIPSEITAALEPIKDNEEAVRAYGVHLGTEMCKKIMASGIKTLHLYTLNMEKSALAIL
TNLGLIEESKVSRPLPWKKPTNLFRLKEDVRPIFWANRPKSYITRTTGWEQYPRGRWGDA
SNASYGALTDHQFMRPRSRDKKIQEEWVVPLKKFDDISEKFTKYCLGQLKTSPWSELDAL
QPETKIIDEQLASINQKGFLTINSQPPVNGAKSDSPSVGWGPAGGYVYQKAYVEFFCSGE
KLNSLVEKSKAYPSLTYLAVNKEGNLVSNVGKTDVNAVTWGVFPAKEIIQPTVVDPASFL
VWKDEAFEIWSRGWAQLYPEDDSSRSLLQEVQNTYYLVSLVDNDYINGDLFNVFKDF
>A0A836T716|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiaceae bacterium|TrEMBL
MEKQYSFELFPPKTEKGMEKLKAVVTELNKLEPAYFSVTYGAGGSTRERTFAAVDWLRDQ
GIDTAPHLSCIGADSDELLDILNRYRNQGIRRIVALRGDLPSGAGLGGTGQFNYANELVA
FINANFPGVFHIEVAAYPEFHPQAATAQQDLDNFKRKVEAGAQGAITQYFYNADAYWRFL
EDCAKREISIPIVPGIMPITNYVNLARFSDACGAEIPRWLRKRLEAYGDDRESLFSYGVE
VVTALCGTLLAGGAPGLHFYTMNQSAAVKAIWNGLGLDGGAAAA
>A0A7Z9TF14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEKIANYKAQGKTFYSFEFFPPKTDFGLDNLYSRIDRMASLQPAYIDITWGAGGSTS
NKTLEMCKTIQKYFGLEVMMHLTCTNMQVSSIKKVLIEAEENGLSNILALRGDPPEGSST
WDQHEDGFRHSVDLVRYIRKEFGNHFCLGVGGYPECHHEQSDLDADISFLKEKVDAGSDV
VVSINDC
>A0A7C1IC18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKTDFLSCLEDHVVLFDGAMGTMIYERGIYINQCYDALNLLKPDLILGIHRDYADAGADV
LTTNTFGANRFMLKKHGFEENIADINRKGAELARQIAGDFLYVAGSLGPPPDRMEPFGKL
SAEDIRTAYHEQAEALLSGGADLLILETFSDLTMITEIIHELKKFYPEVPLIAQMTVDAD
GRTLLGSPPEIFAAGIVNAGADVVGVNCSLGPNRMLQVAEKMIQISPIPVSAMPNAGLPQ
RVDGRNIYFSSPEYFSEYTRRFVQTGVRVVGGCCGTTPDFIRSMRKSLQSIQPRKRIQIT
PVVPDYNPDLDLIPTGKKSRLAEKISRGEFVTTVEIVPPQGADHSKAVEQSRILFEAGVD
AINIPDGPRALSRMASSYLSLLIQQETAGESIQHFTCRDRNLLGMIGDFLGAYAAGIKNI
LIITGDPPKMGTFPDASAVFDLDSIGLTRVAHTLNHGRDLGGNILKKATGFYIGVGVNPG
AVNLEEEIRRLEEKKNAGAEYIMTQPIFDAEEFLGFLDKIKYLNLPVIAGIWPLVSIRNA
EFIKNEVPGAHVPDAVMERLYKTESKDEARETGLSIARETLKELRPYIAGAQISMPFGNV
KYPLEVLKEVLS
>A0A024GR41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Albugo candida|TrEMBL
MSRIITSIQSTYQQHLDLTHKSTARPRPTISFEYFPAKTEDGIFNLLNRIEEMGFTLQPT
FVTLTWRSAFKDASLWLRIGAHIQKCFELNVLMHLTCHLSRESIREILIQAREMGICNIL
ALRGDPPIGKDRWVANRDGFNNAVDLIQFIRQEHGDYFCIACAGYPEVHTEAWNQPEYLP
PSKEAKSLDLERLKMKQDAGADFIITQFFFDVDNLLCWVQDCRTAGITIPILPGYLPIQN
YNSFVKFTQWCKTRVPGTILKTLDTIQNDDTAVKEYGTRLAIETCERILKAGIPSLHFYT
MNLATTVTKILCGLDLIPSPSERELPWHTTILRRNVTKAVAGKSNSELNEKQMRNISDGN
RESNGHLRKSKDERVRPIFWSNRQASYIARTSGWDDYPNGRWGDRTSPAYGEISEYYLAF
KRPKLNRLEMWGKPASESDVWNVFVRFLSGQVTQLPWCEQALSKESSFIREKLKWINQHG
FLTINSQPRVNGASSRDSAVGWGGADGFVFQKAYVEFFCSPLWIHKLLKAMEAYPTLSYH
ALDRQGNEFRNKPADSVTAVTWGVFPGREVLQPTIVDTSSFGAWKDEAFELWQTQWATLY
EKDSETFQVIQAICSSYFLVNIVDHDYTNENSDIFRIFTQLIADEMSKEALHDRMFDLEH
TNERLHENVTQLIHLQDTLMGDLKQAHAGMESLRRENDTLALRVRQLESQLASPQTRSIF
T
>A0A7L3ZLV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Circaetus pectoralis|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQESGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRYLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VEQAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7X0KIQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter aganoensis|TrEMBL
MTPPRPRQTDEHPDGIDLPLDRLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPYDFRPVHLGKKIAAGAQFVQSQYCFDVPMFRTFMQRVRDLGYAEQCF
ILCGVGPLASAKTAKWIRSNVPGIHIPDSIIARLEGAQDQKKEGKQICIDIINEVKEIAG
VAGIHVMAYRQEEYVAEIVDESGVLKGRRPWKREARPDDQLVASRLEHILHDDVTESQVD
MVKTAH
>C9YTY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces scabiei (strain 87.22)|TrEMBL
MREMLATGRTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSVTYGAGGSTRAGTVKA
TEQIAADTTLTPVAHLTAVSHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMADWVAHP
QGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSPDWDSDVARFVDKCRAGADYAITQMFF
QPESYLRLRDAVAKAGCETPVIPEVMPVTSVKMLERLPQLSNAAIPNALKERIVTAKDDP
AAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGPHHPPRA
>A0A2R4BJ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera aromatica K172|TrEMBL
MSTEISIEFFPPTTAEGADKLRTTCARLATLKPAFFSVTYGAGGSTRERSFATVRDIAAA
GFEAAPHLSCIGSTRDSIRAILQDYAGAGVRRIVALRGDLPSGVQDPGEFRYANELVEFI
RAETGDRFHIEVAAYPEWHPQAKSPKDDLAAFKRKVEAGADAAITQYFYNLDAYLYFVDA
ARKIGIDIPIVPGIMPIGSFSKLARFSDACGAELPRWMRKTCESYGDDAESVRAFGLDVV
TRLCEKLLAEGAPGLHFYSMNMAGPTTEICRRLGLAA
>A0A423LHM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFLRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A024GE48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Albugo candida|TrEMBL
MRVIDKINECISKDQVFFSFEFFPPKTAAGVQNLYKRIDRLGQLGPLFCDVTWGAGGSQQ
GSTIEISSNAQKMGMDILMHLTCVNLTSEGAIAALDAARKAGIQNILVLRGDPVRGASSF
KECDKGFSHAIDLIRFIRKMYGDVFCIGVAAHPEGHLHGVDKHQELVYLKEKVDTGADFI
ITQLFYDVAIYKEFVIECRQIGVTCPIIPGVMPIQTYGGFVRMTSFCETRVPDEIKTTLE
PIKDNDEAVKEYGIRLGVDMCRNLLEDGAPGLHFYTLNLERAVRAILSELELVKMSPVRE
LPWHSTCCIKRAGENIRPIYWSNRPESYVARTALWDEYPNGRWGNCESPAFGDLSDSPYV
TANLSAFERREMWGQAPTSTDNITQTFVAYVRGDIKSLPWCNTPLHLETQSIREQLISIN
KNGYWTLNSQPKVNGAPSKDPVFGWGGDHGYVYQKAYIECFTSPQQLRKLMDRASEINSI
QYYAIDSKGNSYSNAENSVIAVTWGVFRDKEILQPTIMDRASFIAWKDEAFSLWNSMWGS
LYEKESDSQKLIHDIHDSYFLVSIVENDFVHGDIWALFSDGLNELKSDN
>A0A5N7MQJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga tunisiensis|TrEMBL
MSPLTLRPSRQVSCPIKVSFEFFPPKTPEMETTLWASIQRLASLNPQFVSVTYGAGGSTR
ERTHATVSRLVQETHLKPAAHLTCVAATKEDVNEVVRSYWDAGVRHIVALRGDPVSGIGT
AYEPHAGGFQQTCDLVAGIKAIGDFEVSVSAYPEKHPEAASLDADIDVLKAKVDCGADRA
ITQFFFDNDHYFRYLDRVRARGIDIPIVPGIVPVQNFKQTANFASKTGASVPDWLAARFE
GLENDVETRKLVAAAVAAEQVIDLVDRGVNEFHFYTMNRADLVYAICHLLGLRDQSVKAA
A
>A0A5E6YIC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDINNFVRKAHAGADSAITQYFFNADSYFR
FVERVQAAGVMIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A4Q3ENI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriaceae bacterium|TrEMBL
MKITDHIANANGKTLFSFELLPPIKGQGIQGIFDAIDPLMEFNPPFIDVTTSREDSYYKE
RDNGLLEKLTYRKRPGTVAVCAAIMNRYKVDAVPHLLCGGFTKEETEYALIDLQFLGIDN
VLVLRGDARKGDTGFVPTPGGHKYATELLEQVHNMNKGKYLHEDHEAFKTNFCTGIAAYP
EKHFEAPNLKSDFQFMRKKVDLGADFMVTQMFFDNSKYAEFVKGCQENGINIPIIPGLKP
LTTAKQLINLPKIFHIDIPEALSDAVQSCKNDKEVKEVGIEWMINQCKELKEMGAPVLHF
>A0A415UX83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF31-11|TrEMBL
MRVDEVFKQAASLGTVPVSFEMFPPKGELTLDTARKVAGSLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCIGRTHADIAAKIDEYRTAGVNNILALRGDLPAGAT
EDDKPASEYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLSLSVEYLKQKQDSGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMSKSQISRMVFMCGASLPSPVIKILAK
HENDPESLQAAGVDYAARQLCDLKEHGVGGLHLYTMNRPAIAATIMERLG
>A0A0Q4XI44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. Leaf93|TrEMBL
MPTASHHRASRDGYRPIQVSIEFFPPKTDEMEKVLWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMIKETSLKPAAHLTCVDATREEIDEVVQSYWDAGVRHIVALRGDPQDGVG
TAYRPHPGGYARTSDLVAGIKRIGDFKVSVSAYPEKHPEAATLDADIDALKAKVDAGADQ
AITQFFFENEVYLRYVDKVRAAGIDIPIIPGILPVQNFKQSANFARRTGASVPYWLAARF
EGLDNDVDTRRLIAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKV
AAAKAA
>A0A0D0RXV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKIPAAPHLSCVGDSKNDLRGLLTHYQQAGIQRIVALRGDLPSGMGMASGELRYANEL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0B7DFG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKGDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A4Q5QI46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriaceae bacterium|TrEMBL
NVLVLRGDARKGDAGFVPTPGGHTYATQLLEQVHNMNKGKYLHEDHEAFKTNFCTGIAAY
PEKHFEAPNLKSDFQFLKKKVDLGADFMVTQMFFDNSKYAEFVKGCQENGINIPVIPGLK
PLTTAKQLINLPKIFHIDIPEALSDAVQSCKNDKEVKEVGIEWMINQCKELKAMGAPVLH
FYTMGNAEPTKRIAKEVF
>A0A2T3NSM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium sanctipauli|TrEMBL
MGYSHASHLDALNQNIADINGDINVSFEFFPPSSEKMEQTLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLVAAPHLTCIDATRDELRTIARDYWSNGIRDIVALRGD
LPAQGVKPDMYAADLVELLRAEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNMTQAKRFAGINNVKIPHWMEKQYE
GLDDDLLSRQMVGASNSIDMVRILSREGVKDFHFYTLNRAELTYAICHTLGVRAAAQ
>A0A6L6Q2U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia ginsengisoli|TrEMBL
METHNFSIEFFPPKTAEGAEKLRATRAKLSELHPKYFSVTFGAGGTTQTGTLDTVREIMA
AGEEAAPHLSCVGGTRDSIRAILNEYKSHGIKRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQARSPQHDLDAFVRKVNAGANAAITQYFYNADAYFQFVE
QATKAGVTVPIVPGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTDLAQRLLKGGAPGLHFYSMNQAAPTTALWQRLV
>A0A3U8PGC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella berta|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGQPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A853G5A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parapusillimonas granuli|TrEMBL
MSSKKVVSLEFFPPRDAAAQEKLAESARKLLALRPAYVSVTFGAGGSTRTGTADTVRMMQ
KLGCEAAPHLSCIGSARAVLGNILDSYREQGVRRIVALRGDLPSGMGGDPGELHYASDLV
SFIREHSGDWFHIEVAAYPEMHPQASSAQADLDHFIGKVNAGADSAITQYFFNPDAYFDF
VERVHAKGVDIPIVPGIMPITNYAQLARFSNMCGAEIPRWMRLRLMDFGDDKASIRAFGV
DVITRMCQRLLDGGAPGLHFYTLNNAEVTTAIWRQLDVGPKQAELQGATLRSA
>A0A1C6B400|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MKMKELFDRGEFAVSAEVGPPKGIHVDELVEEAKTYLTGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMFGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A372GW50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenibacter sp. P308M17|TrEMBL
MKVTEHIKKAEGKTLFSFEVIPPVKGRSIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
KGGLLDKRLTRMRPGTVGICASIQHKYGVDTVPHVLCGGFTKEETEYMLVDCHYLGIQNV
MALRGDARKEEQYFNPTEGGHAYASDLVKQIYALNKGNYLHDKVETVHSADFCIGVAGYP
EKHMEAPSLITDLKRLQEKVEAGADYVVTQMFFDNQKFFEFVEAAKKKGINVPIIPGIKP
IAVKRHLQLLPQVFKIDLPQDLIDAVDECSSNADVRQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIGAIAKELF
>A0A533BL89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPRRLKDVLDQGQFAVTIEYNPPKGTNISGVLENAKQLVGRVHGVNVTDNTAAIVRA
GSLPVCRLLYELGHDPVMQMTCRDRNRIAIQSDLMGASMLGIHNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGRDLAGNKLDGATQFTIAGAVTPEADPLGPMLAKFEVKV
KAGAQFFQTQAIYHPEQFASFMKAVRPFNVKVLAGILVLRNAKMAEFMNANIPGVSVPQE
MIDELRAAGPEHAEDVGVDIAVRTIKAVQPYCDGVHIMAIRATHRLADIITKAEVG
>A0A259R4A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium 14-68-21|TrEMBL
MPPISFEFFPPKTDEQRAQLDRTASLLKARRPEYASVTFGAGGSTLSYTGETVARLHGEH
GLDVAPHLSCMGGTRREIAELLDGYRAAGYRRIVALRGDLPSGMASPGDFRYAAELVRFI
REHSGDHFHVEVAAYPETHPQADDALADLRHFKAKVDAGANGAITQYFFNADAYFRFVDD
VRRLGVEVPVVPGIMPIGNFSQLKRFSDACGAEIPRWIVKRMQAHGDDAESIRQLSAEVV
AQLCRRLIDGGAPGLHFYTLNRARPTLAILDQLH
>A0A1C6CXB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MKISELFKKKIVLSYEVFPPKPTAPVKTIYDTLNELKKLSPDFISVTYGAGGGKNNNETF
KIASAVKSLGIESVAHLPCIGLTKEDVSDKLQELKERGIENILALRGDIPNDNYVQGDFK
YASDLISYIRSQGDFNIIAACYPEGHIEAKDIIEDIQNLKIKVESGADHLISQLFFNNDY
FYSFRERCQLAGINVPIEAGIMPVVNKRQIERMTSLCGASVPKKFAAMMERYENNPIAMR
DAGIAYAIDQIVDLITQGVDGIHLYTMNNPYIARKIYEAIHSLRIKTISEN
>A0A1G9EK93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronincola ferrireducens|TrEMBL
MSLLKEVLERGEFAVTAEMAPPKGIDLNHLMECARAIKGRVHGVNVTDFQSAVMRATSLV
TCKLLKDEGLEPVLQMTGRDRNRIAIQGEFLAAGVFGIKNVLSLTGDHTVVGDHPQAKPV
YDLDSVGILQTATIMMDGKDLVGNDLQGTPEFFLGACVTPRFDPVEAQILKMEKKINAGA
KFFQTQAVFDIETMREFREKTKHLDTKVLAGIIPLKSAAMAKFMNNNVPGIYVPEELIER
MKNTPKEQRVAEGIKIAGEFIQQLREENLCDGVHVMAIGAEENVPAILDAAGL
>A0A495GIQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. BL17N1|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLATLKPKFVSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLDNFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCRRLIDAKVPGLHFYTLNGAAATKAICERLAV
>A0A1W9PYJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfococcus sp. 4484_242|TrEMBL
MSAKTPSRLEKILDSGQLAVTSECGPPRGSDIGVITKKAEMIRDYVDAINITDNQTSVTR
LCSLAACIHLKQMGLEPTLQMVVRDRNRIALQSDILGAAAFDIHNILCLSGDHQKFGDCP
QGQNVFDIDSMQLIQAVRYMRDEGKFLGGDDIQRPPRMFVGAAANPFADPFEIRVPRLAK
KIAAGAEFIQTQCIYNVDKFEQWMKLARDRGLHEKVHILAGVTPFKSAGMAKYMKNRVPG
MDVPDEVVKRMAGAPKEKQPDEGIAICVETIKRLKECEGVRGFHIMAIEWEEKVPEIVEQ
AGLYPRPTMAE
>A0A3R9BVB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter soli|TrEMBL
MTKRVPISFEFFPPKTDIGAEKLITVHQELQQLQPEFFSITYGAGGSTRERTLAAIKEFN
GKGTPVAPHLSCIGDDKARIAELLDLYVAQGINKIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAETFDQDIQRFTEKVNAGANSAITQFFFNPDAYFYFL
DRLQKQGITIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSRSIRAFGHE
VILKLCERLIDGGAPSLHFYTMNTTEPTRQLVVDLGLN
>R5XL19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. CAG:257|TrEMBL
MKITEAFERGEFAVTAEVGPPKGIHIEGLLEEAKTYLSDITAVNVTDNQSSVMRLGSLGV
CKALKDEGLTPIFQLTCRDRNRIALQSDLLSAAMLGIENLLLLTGDHTKMGDHPQAKPVF
DLDSVSLIHAVKQLESGVDLGGNQLVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQIGIIIPKSVGMARFMNANVAGVHVPEDMINE
LKADKEKTKAGITGVEIAARIIRECKPYCQGVHIMALGWESKVPEVLKLAGI
>A0A4R6VLX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesocricetibacter intestinalis|TrEMBL
MGYAADIDTLNQHIADLNGNIDVSFEFFPPKNEKMEQTLWHSIHRLKGLKPKFVSVTYGA
NSGERDRTHSVVKRIKQETGLEAAPHLTGIDATPQQLKEIARDYWDNGIRRIVALRGDEP
KGYAKKPFYAADMVALLRSVADFDISVAAYPEIHPEAKSAQADLINLKRKIEAGANHVIT
QFFFDVESYLRFRDRCASVGIEAEIVPGILPVTNFNQLQKMAKVTNVKIPAWLAKMYQGL
DDDPTSRNLVAASVAMDMVRILSREGVKDFHFYTLNRSELTYAICHTLGVRPD
>A0A5D0UTL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. MP36|TrEMBL
MALGLPSVFPNPQPAIGELIRDGQPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGNPGGEWVRHPEGVEYAEELVRLVRDAGDFSVGVAAFPYKHPRSSDVASDTKYFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQMGTIERSVQLSGAPF
PPALAERFARVADDPEAVRRLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWQQLQ
AAARV
>A0A1J9QI08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomyces percursus|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDDQDDPELLMEHLKEKVDAGGTF
IITQMFYDVDNFLTWVEKCRRRGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPAWLEAL
EPVKNDDAAVRNLGKSLVADMCKKILASGIYHLHFYTMNLQQATKMILDELGLIPSHKTP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSIKELSEIFIRFLDGSLDRLPWSEGAVTEETEIIKSDLLD
LNRKGFLTINSQPAIDGMSSSHPIYGWGPKNGYVYQKAYLELLISPTMIDDVTNRIEQNS
DLTYYCVNKKGELKTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHAPSSPSRRLIEQVMDTWYLVNIVNNDFHKTHDIFNLFKDLKVENLDTEIEPSP
>A0A4R7G5L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rahnella sp. BIGb0236|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLRPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRQIARDYWESGIRHIVALRGD
LPPGSGKPEMYATDLVQLLKEVGDFDISVAAYPEVHPEAKNAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPHWMNSLFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPDIAVPV
RA
>A0A6A6CJE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zasmidium cellare ATCC 36951|TrEMBL
MHITQKMAAAHSKGQQTFSFEYFPPKTAQGVQNLYDRMDMMHGLGPAFIDVTWGAGGRHS
TLTCDMVKTAQAVYGLETCMHLTCTDMERSKIDDALKEAYNAGCTNILALRGDPPREQEK
WEQTEGGFRYARDLIHYIKKTYGDHFDIGIAGYPEGPDETTNADEHIVYLKEKVDAGGTF
IVTQMCYDVDIFIDWVKKVRAAGVPESVPIIPGIMPISTHAALIRRATWSQCRIPPQWHE
VLEPIKNDDAAVRDVGRDLIVEFCQRLLDFGIMHLHFYTMNLASACKMVLEKLDMVPSAG
SPNPDLKPLPWRQSLGLNRRDENVRPIFWRNRNRAYVQRTQEWDEFPNGRWGDSRSPAFG
GLDEYGIGLKGTNEHNRKLWGEPKSLKEISDLFVGFMRGKVESLPWSEAPINEEANVLVN
DLVDLNSRGIFTINSQPAVDGAKSNHPIYGWGPPNGYVYQKQYLEVLVSPDLIDTVVERM
NKDEDITYYAVNSSGELKTNAGQEGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYH
LGAEWSKCYDENSESRKLIRDITQNWYLVNIVHNDFRQDQGIFPLFKGLKAPGFDGEPLT
NGYHHETNGKPQVNGLPNGDHQATSNSSLKN
>A0A6A6CY95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zasmidium cellare ATCC 36951|TrEMBL
MDKLTDKIAALPPNSNYFSLEFFPPKTQQGFSNLNARLSRMAQALRPLFVNVTWGAGGST
SQKSLALAEITQRELGLTTCLHLTCTNMSRKLIDEALDQAKVLGIRNILALRGDPPRSEE
YMDDSDPKAQEDDSNRDFNWAVDLVRYIKKQYGDYFCVGVAGYPEGHSDQSHPEDQSVEH
DLPYLVEKTAAGADFIMTQLFFDVDAYHKYEKRLRGHESGVFKTIPLIPGLMPIQSYQIL
RRTTKLSHANLPTDILKRLEAVKGDDEAVKRVGVDILGEIVESMKKSDSVGPRGFHFYTL
NLEKVVAQILERCDLIPPEPAPQEADGAVAIEESDEFVIVDDAKKKAHRRKSSVANSQAR
NRVIVSHTRASSVSSNRTSAFEAFDDEAGVPKEKINSRANNLAISEGKGSLGREATWDDF
PNGRWGDARSPAYGEIDGYGVSLHVSVPEAKRLWGEPTSAEDISTSFRRHLEGEIDSMPW
SEESLQPETLTIKDKLLALINKGWWTVASQPAVNGVRSTDPVYGWGPKNGFVFQKPFVEF
FIPSADWKKLQGKLDQHPQITYFAGNGKGDFISSDEESVNPVTWGTFTGKEIITPTIIEA
VSFKSWQEEAFGIWAEWQRIYRPGSESSKLLERIRKDYWLVSVIHHGFLEEGALWDDLLK
E
>A0A6A6SFE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massarina eburnea CBS 473.64|TrEMBL
MERITDKINALPEGANYFSLEFFPPKTQMGFANLQSRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRSLVDEALEQAKVLGIRNILALRGDAPRSEE
YREEGQTPEEDSNKDFTWAVDLVRYIRRQYGDYFCIGVAAYPEGHSDESHPEHQSPKTDL
PYLIEKTQAGADFLMTQLFFDVDAYDRFEKMLREHESGTFKTIPIIPGLLPIQSYKILRR
VTKLSHAKLPADILARLEAVKTDDELVKQVGVKVLGEIVEQLKKSPSPGRRGFHFYTLNL
EKAVSHILEDCALIPQPLFEDDNEEAIESTPAINLQPYSAQSDRSRRRLSSVNSSPHNRV
IISRPSASKSSNPSYEAYETEAGIPKGPINTRANTLAISEGEGSLGREATWDDFPNGRWG
DARSPAFGEIDGYGPTLHVSTLQALKLWGHPVETDDVSKLFRRHIEGDLEAIPWSEQGLS
AETSTIAAELLSLNAKGWWTVASQPAVNGLPSHDPVFGWGPKNGFVFQKPFVEFFIPSKD
WKALQPRLKEHEQITYFASDAEGTFEASDEHGVNPVTWGTFIGKEIVTPTIIEGVSFRSW
CEEAYSIWREWRRIYPTKSASSKLLGQLRQDMWLVNVIWGDYVDGDGLWKFLVE
>A0A402AUF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyobacter kobayashii|TrEMBL
MGTELYARGISYERCFEHLNLTNPELIKSIHLDYVAAGAQIIETNTFGANRYRLAEHGLE
NQVVEINRAGAKIARDVRDLSEQPIFLAGNIGPLGSPLAPIGNIQPADARAAFAEQTEAL
LQSGVDLLIIETMSDLAEMREALMAVRSVTDLPVVALMTFGEDGTIISGEDAHAVASTLR
DLGANVFGVNCALGPASMFDVAKSMCKYSTEDFFVAVQPNAGLPRRVGNRFIYVATPEYF
AEYTRRFLGIGIRLIGGCCGTTPRHIAAMHEVLSELAPTISPEADAQSNTTTLEALRERM
QENAAQNTEEQPVTQLAARLQEGRFVISIEMSPPRSVKFTRFLQNATFIHESGADTINIT
DNAMARVRMNNVAAARLIQHNVGIETIVHFTPRDRNLMAVQSDVIGAYATEIRNILAVTG
DPPSHGDFPNSTGIWDVDSIGLISILNNLNKGLDGNRRKLAASTSFFIGCAANPAATDLE
LELERLQRKITGGAQYIMTQPVFDAGTFMHFINKYQDLYGEISIPILVGLQPLHSYQQAE
KFHNEVPGIVIPEEIRNRLRQAGEAGGAVGLEIIKELFDKLQPVVQGAYIMPLDRFELIS
ELIPYIRQRTTRQ
>A0A3N2HR50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frigoribacterium sp. PhB24|TrEMBL
MPTFSFEMYPPRTPANADALHASLRQLAATGPEFISVTYGASGSSRSESLAVLTEVLRDT
DVQAMAHLTCVGSSYAEASRLIREFLDAGVTAFLALRGDPPAGLTEADAFLGDLGSAGEL
VQLIHRVQAERVPFVENAVPGNPFASRLSSGPKTTVAVAAFPNGHPRSRSSRQDIDTLLA
KQAAGATLAITQLFFEADDYLVFVDRAREAGVTMRILPGLMPILGAGQLRRIVELTGDTL
PADLLRRLETADQPTVVGVDHAVHIGRRLLAGGAPGLHLYTFNRHEAPLAVLRGCGLLDH
CVPSTPTTPVDTLLRATPVLETASPSSS
>E3D9T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis (strain ATCC 14019 / 317)|TrEMBL
MQDAGSIFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A521MRZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbiconiux sp|TrEMBL
MNVALERRTACPKHMEYGPCGGVEFDGTCEVGDFRCVFLDVDTVRWHGIAPNPEWQAALE
VSPADGESPQRVGVHIEVRQLADAHEFPVDPQPGAAAMRALLGTRQIVVADFPGKPIDRA
SLLDCAQALAGRVDATLAGDSGRSRVQFPPAYRAHLIQDAGLAVWTGMNCRDRNRVAIEG
ELAGLAEVGVAGVHCVTGDHTATGDRQDALPVFDLDSTQVAALARQAGHLVSVGESPLTP
PVEKRAARLAEKVRAGADVCFVNHAGGAEPVRRFIRASHETGVAPAFIPCVPMVIDRGSA
ALLKSFTTLVLPDGFLDGILDAADTYRAGLDATLALCEELLQLEGVAGVNLSGGASAGGE
VAFADAMATVADRLGLRR
>A0A1M3QSB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium 66-474|TrEMBL
MTPISLEFFPPKNDEQRAQLERALPKLKALAPEFASVTFGAGGSTLTQTPRTVRHLREVH
ALEVAPHVSCMGGTREEIGALLANYRELGCKRIVALRGDLPSGMASPGDFRYASELVDFI
RREHDGWFHIEVACYPECHPQSDHVLADLKHFKAKVDAGADGAITQYFFNADAYFRFVDD
ARAAGIDIPIVPGIMPIANFAQLRRFSEMCGAEIPRWIGKRMLAFGDDADSVREFGADVV
AAMCRRLLDGGAPGLHIYTLNRARATTAVLQRLDGPVDA
>A0A2A2TF66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix elsteri CCALA 953|TrEMBL
MLDTLKSTALSSFRSAARSGEFLVTAEVCPPKGGNPEHMLKMAATLKGRVHAVNITDGSR
AVLRMSSLIASAILLQHGIEPICQFACRDRNRIGLQADLMGAHALGIHNILALTGDPVKA
GDHPDCKGVFDLEAVRLLQVIQKLNLGVDFNEKPLTDGALDLFTGAAVDPQCASWSGLQS
RFEKKLAAGAQFFQSQLITDFDKLEKFMDAIASGCNKPILAGIFLLKSAKNAEFINRVVP
GVNIPQHIIDRLAQAKEPLEEGMKIAAEQVQTARQLCQGVHMMAVKREDLIAPILDMAGV
GVVR
>A0A3S0IID5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum griseum|TrEMBL
MTATPSVSFEFFPPKTEKMEQSLWQSIRRLAPLSPSFVSVTYGAGGSTRERTHATVCRIQ
AETGIPAAAHFTCVGATRAEIDAIARTYWDAGIRHLVALRGDPPDAVGGVGGAYEPFPGG
YAYAADLVAGMKRIADFEISVAAYPESHPDAPSAQFDLDNLKRKVDAGATRAITQFFFDN
DVYFRFLDRCAAAGITVPIVPGILPITNFARAVEFAGKCGASMPAKLAETFEGLDDDPET
RQLVAATVAAEQCQALQAQGVNDFHFYTLNRSDLTIAICRMLGVKAQAAPAGDGVDGAGR
>A0A4Q1D1C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobaculum sp. 24CR|TrEMBL
MLVKEILDARTEPVFSLEFFPPKKQEDWDKLFATITNLNPLEPSYVSVTYGAGGSTRERT
HNLVTRIQQETGLTVVSHLTCIGAEKCEIESVLKLYREHGIKNVLALRGDKPADIPTLEE
AIKDFPHAIDLVRFIRENFPEMGIGVAGFPEGHPETPNRMKELEFLKEKVDAGADYIVTQ
LFFDNRDYFDYVERCDLAGITVPIIPGIMPIMSKKGMIRMGELALGSRIPSKLLRKVLEA
SDDKEVAEIGVNWATSQVQELLDHKVKGIHFYTLNLSEATLKIFRNLKRG
>U2JEP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium paucimobilis HER1398|TrEMBL
MKIIDHIKQADGKTLFSFELLPPAKGKGIQSIFNTMDKLMEFNPPFIDVTYHREDYLYKE
HAGGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLLLRGDARKGDADFIPTPGGHAYATELLQQVLSMNAGHYLHEDMESSEQTDFCIGVAGY
PEKHFESPNFNTDFKWLKKKVEMGADFIVTQMFYNIDKYKEFVTKCRDNDIHVPIIPGLK
PLTSKKQLIALPKIFHLDIPEELSDAVDACKTNADVHLVSQEWMVNMCKELIDFGAPVLH
FYTMSNPGPTQKIVEQLA
>A0A525WGE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. CG24E|TrEMBL
MSREPRRLREVLDQGQFAVTIEYNPPKGTNISGVLENAKQLVGRVHGVNVTDNTAAIVRA
GSLSVCRLLYELGHDPVMQMTCRDRNRIAMQSDLMGASMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGRDLVGNKLDGATQFTIGAAVTPEADPLGPMLAKFEVKV
KAGAQFFQTQAIYHPEQFASFMQAVRPFKAKVLAGILVLRNAKMAEFMNANIPGVSVPQE
MIDELRAAGPERAEDAGVDIAVRTIKAVKPYCDGVHIMAIKATHRLADIITKAEVG
>A0A1I3SJD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoflavimicrobium dichotomicum|TrEMBL
MVRKKGLKEYLADSLLVGDGAMATYLFQQGISIGQCNEELVLSNPAFIAHVHQAYYEAGA
RLIETNTYGANRERLARYGLESKVIRINREAVKIARNSVGEDAYVVGSIGSICAGRVAAF
DEEEYRDMYEEQATALLHAGVDGIILETFLDLKELLIAVKAIRPLTDLPLIAQLSMIEVG
RTRDAFTLSDALQQLADHGVDGVGINCRLGPMEILRSLEKTVIPEHLIISAFPNAGRLGI
DDGEMTYKSDPEYFGETAPLLVEQGVRLIGGCCGTTPEHIRQIAQALDGKKPVPRKNPEP
KLIEVVIPEVAEVKLKKNTIVDRVKKERTIICELDPPKDLDIHRFLLGAHRLSQAGVDMI
TMADNSLATARMSNLALGAILKSQLGIEPLVHVACRDRNLLGQQSHLMGLHALGIDQILV
ITGDPTRMGDLPGASSIYDVTSFELIRMVKRLNDGISFSGKPLKQKAHFVVGTAFNPHVQ
KIEAAVARLKKKVEAGADFVMTQPIYDEQGILELYEATKDIGIPVFVGIMPLTGYRNAVF
LHNEVPGIKIPKSVLERMEAQKDKEAGRKEGVQIAKELLDVAMEKFNGIYLITPFSYWQM
TEELTQYIREKDRKCLALEA
>A0A806H1H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium pseudotuberculosis 258|TrEMBL
MSASHIPAAYQRSITEVLKMPSPGRIPFSVEFMPPRDAAAEQRLWKAAEAFHDLGTAFVS
VTYGAGGSSRERTMRVAHKLSKLPLTTLVHLTLVEHTEAELVEILNDYAAHGLSNLLALR
GDPPGNDPMAEWLATPGGLEYACDLVELTKKNPETAHFQVGIASFPEGHYRAPTLEADTE
FTLEKLRAGAEFSITQMFFDIEHFLRLRDRLAKADSEHGNKPIIPGLMPITSIRSVQRQM
ELAGASLPRELERQLFDAAKGDEEAHKQDIRKVGIELTTQMAEKLIAEGVPDIHFMTMNY
VRATQEVLHNLGMAPAWGTEHGHDAVR
>A0A7K1X9E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. XHT-2|TrEMBL
MALGTASTRTDRARTVRDMLATGKRTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADTTLTPVAHLTAVEHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNAVF
PDALKERILAAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A7X0KWW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura coerulea|TrEMBL
MRPVRPHRPPTVRELLASGERSFSFEFFPPKTEKGARNLWRTIRELESLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPDGVEYAGELVRMIRSYGDFCVGVAAFPYKHPRSRDIESDTRHFVDKCRA
GADYAITQMFFRAEDYFRLRDRVEAAGCDVPILPGIMPVTQLSTIERSEQLSGAPFPPEV
RARFEAVAGDPEAVRRLGIEHAAELCGELLEQDAPGIHFITFNKSTATREVYSLLDGAGY
GARGSRPPITA
>A0A2H3QAT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS012607|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1V5D0W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdus sp. PtaU1.Bin058|TrEMBL
MSTASNLEKVLKGGNFAVTSECGPPRGADAEVVKKKGSLLAGYVDAVNVTDNQTSVVRMS
SFSASLILKTMGLDPVMQMVCRDRNRIAIQSDVLGASALGINNILCLSGDHQKFGDHPTA
KNVFDIDSMQLIQCIRQMVDDGKFLSGEEIKGKPALFVGCAENPFADPFEIRAMRLAKKV
KAGAQFVQTQCIFNVEKFGKWMEMVRDLGVHEKVYILAGITPMKSVGMAKYMKNSVPGMD
VPDDLIKRMQDTPKEKQAEEGIRICLETIEKVRAIKGVSGIHIMAIEWEQRVPEIVKSAG
LYPRPQP
>A0A4W3HDJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callorhinchus milii|TrEMBL
LRGGDLGQSPEEHCTRQCGGWRRSRWLRQNGGGMNQSRTEPWRLRWEESCSDSSSRESSR
SSTPSLESDRLREKMRRRIESGDKWFSLEFFPPRTASGAVNLLSRFDRMGAGGPLFIDVT
WHPAGDPGSDKETSSMMIASTAVNYCGLETLLHITCCNQSKEQITEHLQKACRLGLKNVL
ALRGDPIADKWQTEEGGFNYASDLVKHIRNKFDDYFDICVAGYPTGHPECTSYEEDLKHL
KEKVEAGSDFIITQLFFKPQTFLKFLKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKL
QVPQEIKDIIEPIKDNDAAIRNCGIDLATDLCKALLTSGAVPGLHFYTLNREVAATEILR
RLGLWIEDPRRPLPWAVSANPKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSS
PAFGELNDYYLFYLKSNCAKEELLKMWGEELVNEEHVFEVFTAYITGESNRNGTKVTCLP
WNDESLAVETNLMKAELQKVNRRGILTINSQPNINAKSSTDPVVGWGPEGGYVFQKAYLE
FFTSSENVTALLQVLKKYEPRVNYHIVNVKSENINNASDLQPNAVTWGIFPGREIIQPTV
VDPISFMYWKDEAFALWIERWAKLYPEESPSRQIIQNIHDNYYLVNLVDNDFPLKNCLWQ
VIEDMFLTNSFCKGLHEFPVCI
>B4SAJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelodictyon phaeoclathratiforme (strain DSM 5477 / BU-1)|TrEMBL
MLVKEILNSAAKPVFSFEFFPPKKDEEWETLFETIAALSPLHASYVSVTYGAGGSTRSRT
HNLVTKIQKETGLTVVSHLTCICSDQEETGAILRNYQEHGINNVLALRGDKPAGTTSMAD
AIKDFPYAIDLVRFIKKEYPDFGIGVAGFPEGHPETPNRMKEIEYLKEKVDAGADYIVTQ
LFFDNHDYFDFVERCALGGITVPIIPGIMPITTRKGMIRMSELALGARVPAALLKKVLTA
ANDDEVASVGIEWATNQVQELIDHHIKGIHFYTLNMADATLKIFNNIHQ
>A0A4W3H8Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callorhinchus milii|TrEMBL
MMVKQRQHNGQLSKSGESCSDSSSRESSRSSTPSLESDRLREKMRRRIESGDKWFSLEFF
PPRTASGAVNLLSRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETL
LHITCCNQSKEQITEHLQKACRLGLKNVLALRGDPIADKWQTEEGGFNYASDLVKHIRNK
FDDYFDICVAGYPTGHPECTSYEEDLKHLKEKVEAGSDFIITQLFFKPQTFLKFLKDCRA
IGITCPILPGIFPIQGYHSLRQLVKLSKLQVPQEIKDIIEPIKDNDAAIRNCGIDLATDL
CKALLTSGAVPGLHFYTLNREVAATEILRRLGLWIEDPRRPLPWAVSANPKRKVEDVRPI
FWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSNCAKEELLKMWGEEL
VNEEHVFEVFTAYITGESNRNGTKVTCLPWNDESLAVETNLMKAELQKVNRRGILTINSQ
PNINAKSSTDPVVGWGPEGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVKS
ENINNASDLQPNAVTWGIFPGREIIQPTVVDPISFMYWKDEAFALWIERWAKLYPEESPS
RQIIQNIHDNYYLVNLVDNDFPLKNCLWQVIEDMFLLKSIEKPLPLVP
>A0A2J8IGX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. AFG7.2|TrEMBL
MSPPSLIDTHPNLSDAAPVALSYELFPPRSPAAAETLWTTIRELETTAPDYVSVTYGAGG
SNRDTAVELIHRLVLETTLRPLAHLTCVGNTPQELAEIVGDLLDTGVRGILALRGDRPQD
GAPPVAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEDHDVEVLL
AKQRSGADFAITQVYFRAEQYADLLTRARRAGVTIPIIPGVMPFTSLRRVKRLGELSGVE
PAPELVARLASANSDAEQHRVGVRATVDLAKAALDAGAQGIHLYTFNEHQSVLEVLDELA
LPRHSRSAGRRSTILQRQLAS
>A0A2N8PLM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces noursei|TrEMBL
MALGTASTRTDRARTVRDLLASGKRSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTAELRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVKHPEGISYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDADIRHFVD
KCRAGADFAITQMFFYPEDYFRLRDRVRAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQRP
>C2GGV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium glucuronolyticum ATCC 51866|TrEMBL
MKTAELFEKKTVFSLEIFPPKKTSSIKTIYDTLDGLEGTHPDFISVTFGAVGAGDNTHTF
PIASTIKKYYQIEGVAHLPAISLTRDQVLQRLHEMESYGIENVLALRGDLPVGGEAPSGH
FPHASDLIAFVKEHTDLNIIAACYPEKHPECPNRVDDIRNLKRKVDAGANHLISQLFFNN
AHFYDFLERCDLAGINVPIEAGIMPVVNKAQIERITSLCGADIPPKFRRMMDRFGDNPRA
MRDAGIAYAVDQIIDLITQGVDGIHLYTMNNPFIARRINDAVSNLISVTPARAAHRKVLA
FA
>A0A4W3HVY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callorhinchus milii|TrEMBL
MMVKQRQHNGQLSKSGESCSDSSSRESSRSSTPSLESDRLREKMRRRIESGDKWFSLEFF
PPRTASGAVNLLSRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETL
LHITCCNQSKEQITEHLQKACRLGLKNVLALRGDPIADKWQTEEGGFNYASDLVKHIRNK
FDDYFDICVAGYPTGHPECTSYEEDLKHLKEKVEAGSDFIITQLFFKPQTFLKFLKDCRA
IGITCPILPGIFPIQGYHSLRQLVKLSKLQVPQEIKDIIEPIKDNDAAIRNCGIDLATDL
CKALLTSGAVPGLHFYTLNREVAATEILRRLGLWIEDPRRPLPWAVSANPKRKVEDVRPI
FWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSNCAKEELLKMWGEEL
VNEEHVFEVFTAYITGESNRNGTKVTCLPWNDESLAVETNLMKAELQKVNRRGILTINSQ
PNINAKSSTDPVVGWGPEGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVKS
ENINNASDLQPNAVTWGIFPGREIIQPTVVDPISFMYWKDEAFALWIERWAKLYPEESPS
RQIIQNIHDNYYLVNLVDNDFPLKNCLWQVIEDMFLLKSIEKGRWSG
>A0A5E8HDH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira yanagawae serovar Saopaulo str. Sao Paulo = ATCC 700523|TrEMBL
MHISQVLQKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEQTGQTIVSHLTCVGSTKEEIREILKRYEKSGIHNIMALRGDPPKGQTEFQKT
ENGFGFAGELVGFIKKEFPNMGIGVAGFPEGHPSTPNRLKEIEFLKWKVDQGADYICTQM
FFDNNSFYDYVERCEIAGIKVPIIAGIMPITSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDSFAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRKIYESLGIRNFDTIV
>A0A2H5XP43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR19|TrEMBL
MVSFREKIEKGDRFLITCEISPPRGPNTESFEERLKEVRGKVDAVNLTDNPMLSVRMTPV
VASLFAIKNGVEPIMQITCRDRNILGITSDLIGAWAIGVRNVLALWGDMPKDGKPKGVFE
VDTTELIKLITGLGKGLDFRGNEINGKCDFFVGAALNPFDEAEKLKENAEKKISAGARFF
QTQPIFDIKSITQFADFVYENKIKVLLGVIITPSEKTLENIKKFAKGMVIPEELEENLKK
YESKEDKEKVAVEFCSKLIEKIKQIKVFRGVHIYSPAKESLIGKLLEILPK
>A0A5S5C6V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus methanolicus|TrEMBL
MDVDALNISIELIPRDTAHLEAELELVQTGYASINAINIPDLLRLSTRSWEGAAQAGRRF
DTCIPHIRAIDFNLKQHFGLPDVLDEHGIDQVLVVTGDPPQDMTRSVYPTTSLDLIRKLK
QARPAMKVYGAIDPYRDNFRAEYDYIQRKLDAGVDGFFTQPFFDLRLMEVYHELMGRQEI
YWGVSPVMSERSRNYWETKNNAIFPGGFEPTLEWNTRFARSVLDYGATTGTNVYLMPIKV
DLKAYLDGIFGTRAE
>A0A3S0QUN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium vallis|TrEMBL
MALKNEARGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWDPDFVSVTYGAGGTTKAPTL
SAVTRFLSQTPLATASHLTCVGATKEETHQMIDTFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGIKIPVVPGIMPIQNLTQLKRFAGACGAVIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGLDEFHLYTMNRAPLVSAVLDNLGFTRRAPKSAGAAA
>A0A3T0VRT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hahella sp. KA22|TrEMBL
MESQTQFKRRFSFEFFPPKTPEGMEKLQAVRDKLAKRKPDFFSVTYGAGGSTRERTIDTV
LTLHRQGISTAPHLSCIGATKESIGELLDLYRSNGIQRIVALRGDLPSGMGAPGELRYAN
ELVSYIRERTGDHFSIEVAAYPEFHPQAQSAEADLNNFRRKVEAGATSAITQYFFNADSY
FYFVERCEKAGLNLPIVPGIMPITNYSNLARFSDMCGAEIPRWVRKQLEAYGDDSASIRK
FGEEVVTRLCERLLAAGAPGIHFYTLNQAEPSLAVWDNLNLGDKISF
>A0A7J6CV55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Onychostoma macrolepis|TrEMBL
MVNQRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPKGHPEAESYEDDLRHLKEKVDAGAHFIVTQLFFRAETFLKF
LKDCRDIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIKQVIEPIKDNDAAIRNYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAISAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDELERVNRRGV
LTINSQPNINGKPSSDPIVGWGPPGGYVFQKSYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGRNITNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFVLLDSPQETQEEGSDS
>A0A7Y5W3Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pirellulales bacterium|TrEMBL
MIAPKDGVSFRSMLSGGHFYYGAEVVTTRGFAPEGTQDQLVGMSSELLADPRIGWVSVTD
NPGGAPMLPPDYLAGKFSGRQSQMVLHLTCKDLNRNGLEAAAWRYAAEGFENILAITGDY
PTTGFGGLADPVFDLDSVGLISLLRSMNRGLKIPSRRGGTETFPKTNFFIGCVVSPFKRH
ERELMPQYFKLVRKLRIGAEWVIPQLGYDMRKFHEVKLMLQSRGIDVPVIGNVYLLNRAV
AKLFNSGQLAGCVVSDALMETVEKYAAGPDKGRAFFRELAAKQLAVFKGLGFSAGYLGGI
SKAATFGEIIDLAESYGPEDWREFLKEIQYSQPGEFFLFDHDPQTGLAAPDRINPEYLRS
LDRPPKSKEVTLWYRMSRLVHDVAFTRGKGLYGFLQRVFGRWDKKPGLMSRFSYWLERES
KHLGYGCQDCGDCSLPDCAYLCPLAHCSKGSRNGPCGGSCGGRCELDDKECFWARIYERL
KYYGESQEMFVGPAVLYDARLKHTSAWANTYLDRDHHASAAPAESADDEPSLENGGTTKD
GN
>A0A6N9Q456|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chengkuizengella marina|TrEMBL
MKPDLRELLKNNIITGDGAMGTYLYNLGFPVGISYEEFNIIKPDVIAEVHRKYYEAGARL
IETNTFTATREKLSKYGLENEVKAINRAGVEIARSAVGEDAYVVGAIGSIRAGRRNNIST
EQLRKDFEEQVDALLNGIVDGFMLETFFDLDEAIIPIQIIRSKSDLPIICQFAIEDAGRT
SDGFSISEAFDQVREHGADIVGLNCRSGPNLMLRTLENVTLEEVPLSVFPNAGIPDYVDG
EYTYMASPEYFAQSALRFAKLGAKIIGGCCGTTPEHIAAITDALKSFDPLDYIPYTSKAT
KDLRTNHKTSNFNNILEEKKPTIVEIVKQRHTVIVELDPPRDLDISKFMLGAEALKQVGA
DAVTMADNSLAVTRMSNLALGQLIKEKHDIRPLVHIACRDRNLIGSQTHMMGLHALGIDH
VLAVTGDPARFGDLPGSSSVYDTTSFEMIRMIKQLNEGISFSGRPLKQKANFVVGAAFNP
NVKHLDKAIKRLERKIEAGADYIMTQPVYDPILIKDVYEATKHLKTPIFIGVMPLASERN
AEYLHNEVPGIQLSDEIRKRMVGLSGEEGRREGVEIAKELLDTAVSYFKGIYLITPFMSY
KMTTELTQYVWLKTNHDNYLYPISK
>A0A7W9H1Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces caelestis|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSTDWDTDVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDRVSAAGCDTPIIPEVMPIASARSLERIPSLTNAAF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHRPQA
>A0A846XM27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia speluncae|TrEMBL
MQSLDRHAGAGVPFSVEFSPPHDEAGEQRLWRAVRTFERMHPAFVSMTYGAGGSTRDRTV
RVTGQLAEETTLLPVGHLTAVGHSVAELRSIVGAYADSGITNILVLRGDPPGDPLGEWEK
HPDGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLDCDTAYLAAKLRAGAEYSITQM
FFDVDDYLRLRDRIAALDPVEAAKPIIPELMPITSLRTVERAEQLCGRPLPERVLERLHR
AAGSGAEEDRAAVRAAGIEIATEMGERLIAEGAPCLHFITLNFAKATSEVLTNLGYGVTA
APLIA
>A0A8G2C297|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomicrobium norvegicum (strain DSM 1741 / NCIMB 8310)|TrEMBL
MRIAQLLQQQEPFLSLEFFPPKDRAQWPGFFDVVRQLRDLGPLFCSVTYGAGGSTQHNTL
EIVTRMKQEYGLEPLAHLTCVGADRARIGSFLSGLAQAGVDNVLALRGDPPRGESTFTPD
SEEFQHGSDLVSFIRQDFSDLSIGVAGYPEKHPEAPSMDDDLERLRHKVACGADFIITQL
FFDNDAYFDFVARARAVGIGVPIIPGILPVQNLAALKRMLSFCGASVPEGYMSDLEHVHK
VYGESGVRGLGLGYAKSQIRNLLDRGAPGVHLYTLNKADTCLDIWKDFLRRDGLK
>M7MZ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paeniglutamicibacter gangotriensis Lz1y|TrEMBL
MTTDHPGTTSGSLLDGFSLEMTGKDIPALEAAAPSLPPGTPVNVTFLGNEDLSMRVAAAA
AVKRAGLHPVPHISARRLASTGELDSFLEALERVGSAHHVFTVGGDPAEPMGPFSDSLSL
ITSGRLEAFGVNKVSIAGYPDGHSGIEVDVLWSVLEAKVAALRERGLEGEIITQFGFDTV
PILDWLTTLRDRGISLPVRIGVPGPAGIKRLLGYAGRFGVASSAGIAKRYGFSLGNLLGT
AGPERFIEDLARDYQPERHGEIKLHFYTFGGIETTATWVAAHR
>A0A0T6UU25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. TTU2014-080ASC|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMTVARQLASYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLNQYKDAGIKRIVALRGDLPSGMGMASGELRFANEL
VEFIRNETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVDRVRKLGVDLPIVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDIDSIQAFG
EQVITRMCEQLLEGGAPGLHFYTLNQAEASLAIWNNLQLPR
>A0A0Q4JAT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. Leaf26|TrEMBL
MTLNDPAQDRPGPPLYADLAGDARVSFEFFPPKTEKMEAQLWSAIETLAPLAPKFVSVTY
GAGGSTRERTHNTVARIARDTMLAAAAHLTCVAASKDEIGEIADAYWDAGVRHIVALRGD
PPEVGGTFEPHPQGYTGAADLVEGLMKRHPFEISVSAYPEVHPDAASAQSDLDNLKRKLD
AGATRAITQFFFSPDAYFRFMDKVGAAGITADIVPGIMPVSNFAATRRMAAMCNTDVPQW
MARLFEGLDDHPASRQLVSATIAAELCRKLYEGGVRDFHFYTLNRAELSFAICHLLGLRA
KAVVAQSEEAA
>A0A7C5F8B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium|TrEMBL
MPDHFLKRVQKGIILCDGAMGTLLFSRGVPYQHCFDEVNLSNPKLVQQIHQDYIQAGAEI
IETNTFGANPIKLAIHGLEDKVRDINFRGAKIAREAREITGKPVFVAGSLGPLGKPLQPI
GKISSSEALTFFRQQAEALLEGGVDLFIIETMVNLEEMQQAILAVKQICQLPVVAQMTFT
EEGKTVMGNSPEEVVDVLEALAVDLIGANCSVGPLGIFEVIQRILARTKFKVSAQPNAGL
PRLVDGRFIYLSTPDYFADYAQKFADSGVSLIGGCCGTTPEHIRAMAEVLQARQSSPTGK
SSFENVTIPIPKTDRVEVPGIAELKLSEFARKLKERKFVVSVELDPPKGANPEKILEGAK
AILKAGADACNIGDSPMARVRMSCLALAYLIKDKVGLETVLHFTPRDRNLMGIQSDLVGA
HALGLRNILCITGDPPSLGDYAHATAVYDVDSIGLTRIISKLNQGTDVAGNSIGSPTSFF
IGVGVNPGEENISREIDRFHQKLEAGAQYTFTQILYDVRILERFLKLIGEIEIPIVLGIL
PLHSYKHAEFLHNEVPGISIPDKLRERMRLAGEKGAQEGIKMAKELFHEAKSMVNGVYLM
PSYGRYQEVLEIVEEVL
>A0A352JUC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium|TrEMBL
MAIDLREKLDAGVLICDGAMGTYLNQKGISYDRCFDELNISAPQVVGEVHREYIEAGAEI
IETNTFGGNRFRLAAHGLEQKFRDINLQGAKIAREAREVSGVDLLIAGSMGPLGKPLEPI
GKIKLHDAQLAFTEQAEALLEGGIDLFMIETISSLDETEIAIAAIRQICDLPIVAQMTFT
AEGSTYLGHTPAEMVARLLPLKVDVLGANCSVGPQKMLEVIEQLSELGVGYISAQPNAGL
PRYYGGRFIYLSSPDYFAEYAKSFVKAGALIVGGCCGTTPAHISAVAKAIKGTGITRQLS
SIKVKSSAEAMIVEPFGGAKTRLYEKLKNNFAISVEIDPPKGTNPAKLIEAAIKIKEAGA
DAVNVADSPMARVRMSCLALAYLISSSVDIDIVLHFTTRDRNLMGLQADLIGANAVGIHN
ILALTGDPPSIGDYPQATAVYDVDSIGLVRIISRLNSGMDLAGNSIGKPTALSIGVGVNP
TVPNQELELRRLREKLDAGGQYIMTQPLYELDPLKHFIDKFKPNVPILLGVLPLVSFKHA
QFLHNEVPGISVPTRTCQMMEKAGERSAQVGGELAAEFIEQAKGYVTGVYLMPSFGRFET
CIELVRYIRGN
>A0A6I0DYF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVINILKDSKSTLFSFELLPPLKGHNIQTIFDSIDKLVEFNPAYINITYHKEEVVYRPD
PFGGVEPVKVRRRPGTVGLSAAIQQRYKIDVVPHLICGGFDSHETEDALIDLDFLGIQNV
LVVRGDADKITGKFEPKRGGHRYAVDLVRQVEKLNKGIYLENLMETPKQTEFCIGVAGYP
EKHPESPNFESDIKHLKAKVDAGASYIVTQLFFDNSKYFKFVESCRNAGIKVPIIPGVKP
ISIKEHISLLPKVFGVQIPQELVSAVEKCETNREVYELGIEWAINQAKELKSANVPAIHF
YTMGKSDNIARIASAVF
>A0A6C0P2S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus rhizovicinus|TrEMBL
MLSEKIRNRETGIITYGMTPPKETYPPDQIAEISRKQCERLEGLPIDGLILYDVQEESDR
IDQDRPFPYLRTVEPTTYSRDYLSRLSVPKIIYRCVGKDSESQLSEWLQADPGQERFSVF
VGASSSKQAVSLTLPAAYELSSTVNPKLAFGGVVIPERHQKKHDEHLRIADKIRSGCQFF
ISQAAYNVEAAKDFLSDYYYHCQNQEIDMVPILINLAPCGSAKTLDFMKWLGISIPKWLE
NDLKHSNDVLDKSIRLSQKIFEEIFEFGLEKGIPLGCSVESVSTRKVEIEASIQLVHDIK
ATMEKRMRPAIIV
>A0A7C4G1E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacteraceae bacterium|TrEMBL
MSSSHTPPLPSRAREFRDQIEQRIFIADGAMGTMLYSKGVFINRCFDELNLSNPALVKEI
HDEYVRAGAEILETNTFGATRPRLASYGLAEKLAAINEAGVRLAREAAAATGAFVAGAVG
PLGLHVEPLGPTSFDEARAYFREQIEVLVQAGVDLLILETFSDLNELREAVIAAREAGGP
DMTVVAQVTIDDYGNLADGTDTETYARRLQEMPCDVVGYNCGVGPKITLESVERLMRYTS
KPVSAMPNAGHPSRVEGRNIYLCSPEYMAQYARRLLWAGVRIVGGCCGTTPEHIKAIRAE
ARSLQPEHKDLKTSVETPSAKAQALPKIPMAQKSRLGAKLAAGKFVAFVEILPPRGVDAA
KEVAGARLCAERGIDCINVPDGPRASSRMSAQVACQIIEREAGIETVLHFCCRDRNILGI
QSELLGAHAVGIRNLICITGDPPRMGAYPDATAVFDVDSIGLVNIVNNLNSGLDIGGNPI
GSQTALVIGVGANPGALNLEEELRRFEWKVQAGAEYAVTQPVFDVKMLERFLRRIEHLRI
PVICGIWPLTSFRNAEFMVNELRVPVPDAFMERMRRADTAEKAREEGVRIAQEMVRETRG
MVAGVQLSAPFGRYDMALEVAAAIGPR
>A0A6L8U478|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVIDRLTQLKSTLFSFELLPPLKGHTIQTVFNTIDRLVAYNPAYINITYHREEVVYRPD
SRGGTEPVKVRRRPGTVGLAAAIQQRYNIDVVPHLICGGFDMHETEDALIDLDFLGIHNI
LALRGDADKVVGKFEPKIGGHRYAVDLVRQIDAMNRGEYLEKFMDKPKSTNFCIGVAGYP
EKHPESPNFESDLRHLKEKVEAGATYIVTQMFFDNSKFFNFVERCRSMGIEVPIVPGIKP
ISVREHLSLLPKIFGVHIPEDLAVEVEKCADNRQVYELGIEWAIAQTKELKNADVPAIHF
YTMGKPDNIATIAGSVF
>A0A1V2UPJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter genomosp. 33YU|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPNSIDKVLHFSGKARDIQDFERFLQQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGIAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGYAGIHLSACHKPEEQMLLESYVEQYRHLELKALEELWNSLWQVT
SSKEFSPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGIGRFIFKGSFWDNTLVAK
VLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDHCEFGDRECI
HSVKARLAKVVKQTEVLKEKLIPTVSIETRGTSSWKNWYLGVEA
>A0A847EUW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSVINNILNNKKTAFSFELLPPLKGNSINSVFKTIDTLKEFDPKYINITTHRSELVFKPL
SNGLYQQVAERHRPGTVAVAAAILNKYGIPVVPHVLCSGFTEAETEYVLIDLQFLGITDL
LLLRGDKARHEKAFIPTGHAHATDLQQQVNRFNEGFFMDGTPIKQQGQPFSYGMACYPEK
HEEAPNMATDIHWAKVKVENGASYLVTQMFFDNQKYLTFVEACRNEGITVPIIPGLKPIV
LLNQLTVLPKIFHVDLPEDLTKALSECKTDADAATVGVEWCTQQANELKAMGVPSIHFYS
MMATESVRKVASAIY
>A0A7X6XFE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MQVSRLIKNNEGKTAFSFELLPPLKGNSIQQVFNVIDRLREFDPKYINITTHHSEAVFEK
NKDGNLIKRNIRKRPGSVAIAAAIQNRYGITAVPHMISKGFAKEETEYALLDLSFLGVHD
LLLLRGDTSKLDKEQLAMDSHDHATGLQTQVNNFNKGIAFDGTPFAAPEYPFSYGMACYP
ELHAESPDMESELFYLKKKVENGAEYLVTQMFFDNEKYFNFVELCRKEGISVPIIPGIKP
IHLKNQLTILPKIFQSDIPEALAKELQNCSSDKDAKQVGAAWCTEQCKELVAHKVPSIHF
YTYMASEIVYKVAREIY
>A0A1V2UT27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter genomosp. 33YU|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDVAPLEASKS
YPDSIDKVLHFSGKARDIQDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMTAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKAFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYVEQYRHLELKALEELWNSLWQVT
KGKEFSPEIARFSRQPTSKQIIKYRQLHVMHEAMFGSKIAKGIGRFIFKASFWENTLVAK
VLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEVLKEKLIPTIAIETRGTSSWKNWYLATEA
>A0A5D4SYZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sutcliffiella horikoshii|TrEMBL
MGILDSLQQDKILIADGAMGTLLYSYGSDCCFEELNLSQPNQIYNIHKAYLNAGANLIQT
NTYAANYHKLERYGLQDQVKEINSAAVRLAKRAVADYPDAHVVGTIGGIRAIKPEAIPLE
EIKRTFREQLYCLLLEGVDGILLETFYDLEELETVLQIARKETDLPIIAQVSLQEVGYLQ
NRVHITDALNRLESLGADIVGLNCRLGPYHMISTLEEVSIPKTAYLSAYPNASLPSYVDG
KLEYDSDADYFKETALAFRDQGVRLIGGCCGTTPAHIKAFSDALEGVAPLKEKQVKRKER
TIILPSSKKKDVPTPLFEKAKKQQSIIVELDPPRKLNTDKFMAGAKALKDAGIDALTLAD
NSLASPRVCNTALGSIVKSDIGLRPLIHITCRDRNLIGLQSHLMGLHQLGIHDVLAVTGD
PTKVGDFPGASSVYDVTSFGLINMIKQFNQGVSLSGKELGERTSFSVGAAFNPNVRVIDK
AVQRLEKKIDAGADYFISQPVFSEEKLLEVFQATKHIDAPIYIGIMPLTSSRNANFLHHE
VPGIKLTPQVLEVMNRHQDDPQQASLEGLNIAKGLLDAALELFNGIYLITPFMRYELTVE
LANYAKKYGPFHSSRRVQNV
>A0A729Q6S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. houtenae serovar 18:z36,z38:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6V8MJY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomonas silvestris|TrEMBL
MKIVDQMSQGKQFLSLEFFPPKDKNEWPHFFKVAQRLAELNPLFASVTYGAGGSSQGDTL
EIVTRLKRDHGLESMAHLTCIGTERGALQQFLDELASAEVYNVLALRGDLPQDAGPEVSV
CRSLSHASDLASFIRAAHPEMGIGVAGYPEAHPEATSPEDDLAFLKKKLELGGDFVITQL
FFDNESYFDFVARARALGIQKPIIPGILPVVSLKVIRRIVSLCGASIPPEFLAKLEEADR
AGGAAAVQKLGIAHARSQAAGLLAQGAPGVHLYTLNRDEAILDLVDGLLPGA
>A0A7X8CP28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSVIDRIRNAKGPLFTFELLPPLKGHSIEKVYATIDRLMEFSPAYINFTSHRNETVYHER
PDGLLEKRVVRKRPGTFALAAAVKYKYNIPVVPHVLCGGFTKEETENVLIEMNFLGIDDV
LALRGDPQRGSRTFIPEKDGHSHTWELVQQIVNMNNGKYLEESLEDTAPSNFCIGVAGYP
EKHFEAPNILVDLENLKRKVDTGASYIVTQMFFDNSKFFRFTEECRKIGIDVPIIAGIKP
VSALNDINLLPQTFHIDMPHDLVLALQKCKTDKDAREVGIEWAVMQSKELIRAGVPGIHY
YTLGRSDNVARIVKEAF
>A0A7K8QID6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithornis capensis|TrEMBL
MVNETQHTCSASSSSRSDGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQEAGDRW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNF
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASTEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7X6TD15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKIPDILRRKKTLSFEIFPPKRQEDTFVLIEDTIKELSDFNPDFISVTYGALGNTLNNSV
AIAKHIKQHTHSEPLAHLACVSSNPAQVDEICQELREAKVKNILTLRGDLPADPGMYHHD
FCHASELAAYISQHYSADFAFAGACYPEKHPEALSMKEDIRYLKMKQDAGMDFFITQLFF
DNEAFYRFLLEARKAGITIPIIPGIMPVSNYKQLDGMIKVTGAAIPLQLRNYFDRYRYDK
QALEEIGIIFTSHQILDLIANDVDGIHLYSMNKSSFIKKLMSNIAYVRTGFFAQA
>A0A352ME54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
GLQAIKDQKKVNAGAQFFQTNLIFEPDRLDDWLEQLDKRDVLNKVYIMIGLVPLKSYKAA
LYLHNKVPGVYLPANILQRIEKAGEGAPEEGVRIALELIDKIKGKKGISGIHLMTLGWEE
IVGRIITESGF
>A0A1V6JX66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium ADurb.Bin006|TrEMBL
MRFIHDIYSDARQAGRPVFSFEFFTPKTESGDRAIFERTLPALCRLAPSYCSVTYGAGGS
TRAKTLQMVERIQLEFGVPAMAHLTCVGSTRDQIVALLDEARSRGISNILALRGDPPEET
GRFVRSDGGFEFAHELVTLTRDLGGFSIGVAGFPEGHLECREGKEVDWRRLAAKIGCGAR
FVITQLFFDNAFFYEFRDYLVGTLGITVPIVPGVIPILSSSQVERFVSLCGATIPSALAG
RLNALGDNDADVTEFGIEFATRQCADLLRQGVPGIHFYTLNRTEPTTRIVQNLRGG
>D6DDI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum F8|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A4R2MPC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Uruburuella suis|TrEMBL
MTGSQKKLSFEFFPTRTPEGRAKQVITRKQLSQYNPEFFSCTSGAGGSTKEGTLQAITDI
LSEGVAAAPHLPCVGMQPAEIIELLQQYKEMGVRHIVALRGDIPSGMGSGMSGLRYANEL
VELIKTEFGSDFHVEVAAYPEYHPQARSAEDDLNNFVRKARAGADSAITQYFYNADAYFR
FVDDARGRGVEIPIVPGIMPIASFSKLARFSDTCGAEIPRWLRLKLQSYADDTAAIKALA
LDVVTEMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>A0A564IV93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella spallanzanii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWDSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A316UJJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomicrostroma glucosiphilum|TrEMBL
MASPADTPPESASPSSSSSGPHPAHITSKLQNTPPSSPFWSLEFFPPKTSQGSSNLLSRI
ARMSSDLRPSWLNVTWGAGGTTEGKSLSLAGSCVHGAWEGETINGEPLTEWQGGLDVCLH
LTCTNVEKQSLDQTLRTARKLNIRNILALRGDPPRGEEYWIASDSQFQLATDLVRYIRQE
HGDFFCVGVAAYPEGHCDSIERDVARDVQHLKLKQEAGAQFIITQLFYDVDVFVQWYKQC
REAGITIPILPGIMPIQNYQSFRRMTNLCKATVPEEVLLALEPIRFDDAAVKDYGVQLAI
RIIARLYLETDIRGFHLCTLNLEKSVRRVLQGLGWVRDEQPTRSFEEGLGKGPVAKVKAI
EGMKARAAAINGESSRSEPIDYRTATQGALQRATSKTSQALYSPAIPPDGDATAHTIGNA
SHLTPDYVQNTATTSASSTSWDEFPNGRYGDARSPAFGEIDGYGVSLKVPPQDALRLWGT
PVEEDDISLIFSKYLLARLACIPWCDAPIFDETLAIRNWLLALNLPKKAKSSSSSSSSSL
SGRGWWTVGSQPAVDGVPSSDPTYGFGPRDGGGYVYQKAFVEIFVDEADKEWIREKIEQE
GEGRLSFFAGNRKGDYESNLSLGDVDAVTWGVFPGKEIAQPTIIEEESFKAWRDEAFEIW
GEWEMLFAKETKTRGLLRGVGEGKWLVTVVHHDFKDPTALWRFLGCEEHLPTDEDVARLE
QVWA
>A0A660Q0E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium|TrEMBL
MYVTEHLSRAQNPLFSYEIIPPQRGKSARDILDIVEQLQPYNPPFIDVTSHCANAYYEEL
GDGTLRRRIRRKRPGTMSICGIIQNRYNIDTVPHLLCRGFTREETEDAVIELGYLGIHNV
LVIRGDDTNYVKPVGDNRTTNIYSTDLVRQLADLKEGKYLEEIANPDSIEMCIGVAGHPE
KHVESPNLTDDIMHLKEKVAAGADYIVTQMFFDSGSYFKFVEKCRKAGIEVPIIPGLKIL
STMRQLTSLPKNFHISIPEELVNEISENRKHVKEIGIRWAVRQCRELLEGGVKCVHFFIM
NDAMLVTDVVKQLS
>A0A2D5UDS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium|TrEMBL
MIFRAHERYEKGRVVFMSAIIEEIRSPEVTVSIEVFPPKSENGAARLLEETARIQEGVRV
AFTSVTYGAGGSTRDGTLNLVIELAKRNPGRVVAHLTCVGSNEEALSRLLSAYHESGMTD
IMALRGDIPEGMTREEAVSGGFRYAADLVRWLREAGGVSSIGVAGYPEGHPETPDRAKDL
DYFVAKAGAGADYAATQFFFENSDYFRFVVEVAARGLQIPVAPGVLPVRDIDQVARFAGM
CGAAVPERVLSALEPYRGDPEGFKEKSADLAAEQISGLIEAGVRHFHIYSLNKSDIVLGI
ADRLGWRR
>A0A1W1UPY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella testudinis DSM 23072|TrEMBL
MSYAKEIDALNQSVADLSGNLNVSFEFFPPKNQTMETLLWDSIERLKDLKPKFVSVTYGA
NSGERERTHSIVKAIKQQTGLEAAPHLTGIDATPEELKVIAKDYWQSGIRNIVALRGDEP
QGYVKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQSDLLHLKRKIEAGASRAIT
QFFFDIDSYLRFRDRCAAVGIDVEIVPGILPVSNFKQLQKMATITNVKIPSWMVKMYDGL
ENDQTTRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPNIAE
>A0A350MQV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MHVAEILSKSNKTLFSFEILPPLKGGSFNDIYKSIEPLLEFKPVYINVTYHQEEVVYKDR
GNGLLEKKVVRKRPGTVGIAAALQYTCNIQVVPHMICGGFTREETENALIDLNFLGINNV
LVVRGDPDRSQKTFIPEPDGHIHSLDLVKQIVDLNHGKYLEEDLQNTTPTNFCIGVAGYP
EKHPEAPNKASDLRYLKMKIEAGASYIVTQMFFDNRKYFEFVNDCHEMGINVPIIPGLKP
VATCQHLYLLPKTFGIDLPDDLAKELEKCKTNQEARNLGIEWTIQQTKELIAAHVPAVHF
YTMGRSDNIY
>A0A8C6V2J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neogobius melanostomus|TrEMBL
MVNQVQRGDGTLSSRSDSSAASASGGDSSKESSRCSTPVLDADRTDRLRYKMRRRMESGD
HWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPSGDPGSDKETSSMMIASTAV
NYCGLESVLHLTCCNQSKDNISRHLSKAKHLGLKNIMALRGDPVGSDWEEEEEGFNYAVD
LVKHIRSEFDDYFDICVAGYPTGHPEAHSYKEDLIYLKEKVAAGADFVITQLFFRAETFL
KFEEDCRPSGSPCVCVQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIHQAL
EMCRVLLDSGRVPGLHFYTLNREVATMEVLRQLGMWQEDPRRPMPWAVSAHPKRKVEDVR
PIFWGSRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLVFEVF
TCYIAAQPNRKGHKVMCLPWNDEPLAPETNMLKDELEKVNTRGVLTINSQPNINGKPSTD
PIVGWGPPGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQ
PNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDN
YFLVNLVDNDFPLDSCLWQVIEDMFELLQTGQVANDSSLELDS
>A0A524M9W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MSSYCLSKSKLRRGFCFDTYTNWEFYNLLDTRLKQTLDAGIFAITGEIGPPRGADHNIVI
ERTKLIADYCDAINITDNVRGVPTMSSMACARIVLDAGAEPIMQLSTRDRNRISIESELY
GVYALGIRNILFITGDRTIMGPHSDAKMVFDIDSIQALQLSSHLMGGTNFDGEALEGTPQ
FFMGSTFNPYADSIEKEILRTEKKRDAGALFFQTQAIFDTDRLDSFMELVRDLKLKVLAG
IIPLRGPRMARFMNTNVPGIKIPEEYINRLESAGKGLKEDAERDTMREEGLLIALEIIKS
IRKIKGIDGLHLMGIGWEESIPELVKRAGLSQRPKME
>A0A523S3G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MEICELLDTRFKQLLERGEFVVTGEIGAPHGSDSNLINERVETVRNYCDAINVPDNARGV
PTMSSLVCAQYVFQAGVEPILHLTTRDRNQIAIQSELYGAFALGVRNILFMSGDHVRFGS
HPDAKMVNDLDTLEALSLAKHLSHGVDYAGDELEGTPEFYVGATINPNDDPMEELVDRVE
EKREAGAQFFQTQAIFEASRLEDFMSLVSVDLNVLAGIIPLRDSEMAEFMNEFVPGIHVP
EEVIKRLDDAGRGSNEAARIEMIKAEGIQIALETIEEVRKIDGINGLHLMGVGWTESIVE
LVKGAGLYPRPDRER
>S9V8E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strigomonas culicis|TrEMBL
MVELCKTYLPPDMQATLEELKEKPEELKAYGVRQVVELIRQIKAANIGCNHYHFYTINTT
KQTFGALKEMGILKE
>A0A4D6PB87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000189|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3S4EFY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyvera intermedia|TrEMBL
MSFFHANQREALNQSLADIGQINVSFEFFPPRTSEMEQTLWNSIDRLSILKPKFVSVTYG
ANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGDL
PPGSGKPDMYAADLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFNG
LDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A524CU93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MEMCTFSSPNPLDSSFSIDIKDNKKGPDAVAFDNSMEKTALSRTRLRTLLEDNEFVVTSE
IDLPCGSDASRIIDSADLIKDYCDVINAPDNPMGNPCMSSTIGSHFIIQAGAEPVLQISS
RDRNRIAIQSELFAAHALGIRNILFISGDHSRHGYMKRAKSVYDIDSIEALEMSRELMQG
YNALGEELEGTPHFFLGATFNPYEEPMEEHVLRTERKSEAGAQFFQTQGIYDPARLEEFL
SRVEYLDPKVIAGIIPLQSPEMARFMNEFVPGLVIPEHIIERLEAAADGLEEEESLEATR
PVGIQIATETIAELRKLDGVHGVHIMGVGWLESVIEIVKEAGLFPRPL
>A0A497QGW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MEYKNKSNLEKVLSEGKFAVTAEIGPPKGSDPDQIKQKAEILKGYAHAYNITDNQAAVVR
MSSLAGCCILLGMEMEPVMQMACRDRNRIALQSDVLGASALGIRNILFITGDHQSLGNHP
SSRGVYDIDSIQLIQIVKNMRDNGIFQNGEEILRGNPSIFIGSAANPYATPYEIRVDRLE
KKIYAGVDFIQTQSVFNIERFNEWMDEVRSRGLDKKVHILAGVTPLKSIKMTERMKYYIP
GVDVPDAIEKRMKNASDPKKEGYEIALEIIKEIKKIKGIHGVHITALFWESIIPSLISES
GLVPR
>A0A1Q4DBF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 64-17|TrEMBL
MTLREKLEAGRFVMTAEVTPPVSMARSDLVDRAMPLKGLADAVNVTDGAGARPHLGALTA
AAMLLAEGIEPILQLTCRDRNRIALQSDLMSAAALGIDNLLMLRGDNPDAGDQPEAKGVF
DIDTRTLMTTARELRDKGVLPPSRTVAGHANFFIGGADNPIDPPPGWQPDGLRAKLASGA
QFVQTQFCMDAGVVARYCARLAEAGVARQVHLLIGVAPLKSAKSARWMRDKLFGSIIPDD
IVARMEQASDPAAEGEAICVALIEQLARTPGVSGVHVMAPNNVGALPRVLRAARERVAKI
RG
>A0A1G5VRU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. NFPP33|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRAFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLPR
>F8MCY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neurospora tetrasperma (strain FGSC 2508 / ATCC MYA-4615 / P0657)|TrEMBL
MEKITDKVAALPPDSNYFSLEFFPPKTAMGFANLRDRLERMARGLRPLFVNVTWGAGGST
AQKSLELAEICQRELGLTTCLHLTCTNMSRRLLDKTLEDAKVLGIRNILALRGDPPRAAE
YHDENDPEPTDDEEFSWAADLVRYIKKTHGDYFCIGVAAYPEGHAEEAHPREQSLEHDLP
YLVEKIQAGADFIMTQLFFDIDAYEHFENTLRDHPSGAFKDVIIIPGLMPIQSYQMIKRT
TKLSHAKIPPALMARLDAVKGDDEKVKMEGVAIVSEMIERIKEIKSRTPGPRGFHFYTLN
LEKAVAFIAERTNLIPPGTPDEDESAILPDFPQLRINGSSVPTRSIQDLSTRKGSIGSDP
RDRVIVANQRPSHPDYEVSPLEAGLPAEPVNTRANTLAISEGEGVLGREATWDDFPNGRW
GDARSPAYGQIDGYGVSLHVTVPQALQLWGSPKTTEDINNIFIRHLKGELSAIPWSEEGF
NDETEAIRDNLIELNSRGWWSLASQPAVNGLRSDDGTFGWGPENGFVFQKAFVEFFIPSA
DWRVLEAKLRQPDMKDAVCFFATNAAGDFVSTDTINFRARMAAEAEGTAEADHRPHEPST
NAVTWGVFPGKEILTPTIIEEVSFRAWSEEAFGIWSEWAKIYGKGSDTQKLLEDLKEDLW
LVNVIHHDYLEKDGLWKLLSQ
>A0A6B2UN67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID11385|TrEMBL
MASGTASTWTSDHPTVAEVLASGKPSYSFEFWAPKTPKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRTGTVRATQAIAENTTLVPVAHLTAVEHSVAELRHMIGQYADGGVRNILAVR
GDPPGDPLGDWVAREDGLTYAAELVRLIKESGNFCVGVAAFPEMHPRSENWDSDVRYFVD
KCRAGADYAITQMFFDPASYLRLRDRLAAAGCETPVIPEVMPVTSVRQLERLSRLSTASF
PETVKERMLAAKDDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LPHHRP
>A0A435TYN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.006.01.1.1|TrEMBL
MNTAQSDENLDGFHLPPELLPGHSSQGRLERVLRRGEFAVTAELNPPDSANPKDVYERAA
VFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANILCLTGDGVQAGDQPGAKPVFDLDSISLLQTIRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQTARDLGLTEKVFILV
GVGPLASARTAKWIRSNVPGIHIPDVVIERLERAQDQKAEGKRLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRRPWKREQSADAILIGERINQLLDAEQRR
>A0A4R4X5F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella turkmenica|TrEMBL
MANGLPSTLPGGTPTIRELLATGDRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWVAHPEGLNHAVELVELIRSLGDFCVGVAAFPDKHPEATSLEADAQVLAA
KAAAGADYAITQMFFGADDYFRLVDRAAALGCDIPVLPGIMPVTNIKQIQRMAELTGMAL
PTAVTDRLLAVEDDTAAVRAVGIEIATDLCERLLAGGAPGIHFITLNRSTATRQVFLNLR
SSSPTTALSSLPAQG
>A0A0B5E0J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Celeribacter indicus|TrEMBL
MTRAPAISFEFFPPKNIQACFSLFETVEALQGLDPSFVSVTYGAGGTTRELTHDAVALLN
KEYGWNVAAHLTCVNATKEETLAIARSYKAVGVNEIVALRGDPPKGQGRFTPAPGGFANS
AELVEALAGTGDFRIRVGAYPDPHPDATGPDSDITWLRRKFEAGADSAITQFFFDPDTYF
RFRDRCAKAGITGTIIPGILPITSWTGVQKFAASCGTPLPDRYATAFEAAQSAVDREALS
VDLCTELCETLIAGGVGDLHFYTLNRPTLTKAVCARLGVTG
>A0A1B1Y943|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenyingzhuangia fucanilytica|TrEMBL
MNSQELKKKIENKEGGYLFYGLTPPKISTPVEKIDGISQRQIERIKNLPIDGLVLYDIQD
ESSRTHLPRPFPFLHTWAPDEYANQYLQELNVPKIIYKSVGKFTESSLKEWLVANEDTID
LTVFVGAPSKQQQVNLSLQDAYKIKKASNSTIKLGGVTIPERHFAKGDEHIRLSNKIGSG
CTFFISQCVYNLDNAKSFLSDYHYKTQEKNIAPAPIIFTLTPCGSVKTLEFTKWLGIDIP
RWLENDLTSSEDILAKSIEVCKYIAKELIKFAKEKNMPIGFNIESVAIRKAEIEASIELV
KSVKEMMI
>A0A0K8MGL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructobacillus ficulneus|TrEMBL
MTLIHNFYKDYQPIVSQERIKSEALFQQGEPAGRRVSYQSLVNHSQDQEGFKTLVEYADE
MQKQSQQPVLFHLRAGDVTPTNLVQTMTMFREHGLENLLIISGDQMRLADGYSSAISLLE
AVQVAEITGFDLAATLDVNQVKTQGLKAVVQQALAKEGAGAKVLITQVFFHIEDFLLVQD
ALREAQSKVSLVAGIMENPNPKQLAWVKNVLHGEVPEEWLQDPVQETNRLVAALTAHQAA
GIHYFAQPKN
>A0A7J9ZRY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangiales bacterium|TrEMBL
MADAHPFAHHHAPTVKDMLAQGPTFSFEFFPPKTDKGERSLWRAIRELESLQPSFVSVTY
GAGGGSRDRTVEITERIATDTTLVPVAHLTAVNHSVRELRHLVGRFAAAGVRNLLALRGD
PPGDPQGEWVQHPDGVAYAEDLVQLICASGDFSVGVAAFPYKHPRSPDIDSDTRFFVQKC
RAGADYAITQMFFRAEDYLRLRDRVAAQGCEVPIIPGIMPVTKISTIERSEQLSGAPFPA
ELAAEFETVADDPDAVYRLGIEHATRLGRKLLDEGVPGIHFITFNQSPATRELYQRLGLA
PERIPASA
>A0A7G3F0G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
YEGLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A4Q7KR39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbihabitans rhizosphaerae|TrEMBL
MDSVVQRLRVDRPVFSVEFMPPRSEEDERVLWRAVRELESLDPAYVSITYGAGGSRRDRT
IRTTGRVAQETTLVPMAHLTAVEHSVAELRNVIGWYAAVGVRNILALRGDPPGDPNGEWR
THPEGLSYAEELVRLVRELGDFCVGVAAFPYGHPRSVDLDTDTRHLVRKFDAGADFAIAQ
LFFEADDFLRMRDRVAASGYDGDALLVPGVMPLTTPRTLNKTVELSGAQVPPKVAARLDP
LADDPAAFRAEGIDLVTELCERLIAEGVPGLHFYTLNRSKATREVVARLGLVPGRTATAQ
RLRA
>A0A502DLX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax guangxiensis|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYAQQPEFCSVTYGAGGSTHEGTFGAVREILAE
GVDAASHFSCIGATKATVRTQLGELKAMGVRRLVALRGDLPSGYGVGGEFGHASDLVAFI
RQETGRDFHVEVACYPEVHPQARSPEADLQAFASKVKAGADSAITQYFFNADAYFRFVDD
VRRLGIDTPIVPGVMPITSSTQLMRFSDACGAEIPRWIRLRLQGYGDDTASIKAFGLDAV
ATLCERLRAGGAPALHFYTMNQATATLALLDRLEGSA
>A0A512AS81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adhaeribacter aerolatus|TrEMBL
MKVTEHIKNASSTLFSFEILPPVKGTSIQSIYDGIDPLMEFKPPFINVTYHREEYVFKER
GNGLLEKISIRKRPGTVGICSAIMNKYKVDAVPHIICGGFTKEETENALIDLNFLGIDNV
LVLRGDSIKTESTFRPHPDGHAYACDLLQHVVSMNHGKYLDEDIANPLPTNFCPGVAGYP
EKHAEAPNLATDLKYLKRKVDMGAEYIITQMFFDNKKYCDFVKACREIGINVPIIPGIKP
LTTKNQLKLLPNLFHIDFPDDLVDAIEAATTPQAVRQIGIEWTIQQSKELIQFGVPCLHF
YTMSKSDAVVQIAKAVF
>A0A2T2TDN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QH_8_67_23|TrEMBL
MKVTERLESADEPLISYEIIPPKRGGSAEQIMGVVEELMPYDPAFIDMTSHAAEVEYVES
GDGTWRRRVMRKRPGTIGLCAAIEARYGVDTVPHLLCKGFTREESEDALIELNYLGVDNV
MALTGDDPGYKKDIAPSRSRNEYAVELVEQINDMNQGTYLDELADTAPTDFCVGVGGYPE
KHIEAPNLTWDVLRLKRKVDAGADYITTQMFFDNDAYFEFVERCRDVGITVPIIPGMKIL
SRKRHLQFLPSFFHLSIPEALAAEVEAADDKEEVERIGVEWAIQQAEELMDAGAPAVHFY
IMSSARLAKRVVEPLRENRRKKKGQQAPVEEQPAPVEEAEEVDE
>F9P241|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis bv. 2 str. F0392|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLAKEKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNSETAKYIHQATNALFNHQSLG
>A0A428WXR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis balhimycina DSM 5908|TrEMBL
MTSVIERLSGDGPKFSIEFFPPRDTADEAVLWKAVRELEPYDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYASVGVRNILALRGDPPGDVYGEWV
PHPEGLTYAEELVQLVRELGDFCVGVSAYTYGHPRSPDLETDTKYLVRKLRAGADFAIAQ
LFHDAEDFLRLRDRVAATGCDIPVLPGVMPLTTMRTLQTTIKLSGAPAPRKLLDRLEPLA
DDPKAFRAAGIDVTTELCERLIGEGVPSLHFYTFNRSKATREVIARLGLVPARA
>N0D0V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces fulvissimus DSM 40593|TrEMBL
MSGLRELLAAGTRSFSFEFFPARTEAGAAGLWEVVRRIEAFAPSFVSVTYGAGGSSRDRT
VELTNRIAAETTLRPVAHLTAVAHSVAELRHVIGQYADAGVRDVLALRGDPPGDPNAPWI
PHPDGFSHAWELVKLVRESGAFSVGVAAFPERHPRSADWESDVRHFVAKCRAGADYAVTQ
MFFRAEDYLRLRDRVVAAGCDTPVIPAIMPATDPRQIARFAELSGATFPDDLARRLHAAG
GGEEGRRIGIDFAVAMAEKLLAEGAPGLHYITLNRSSPTSEIHRELLGSALTAPALTAHA
>A0A662LDT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MKLKESLEKKKFVVTSEVQGAVDEAPEQLVKSLELVRGRVDGVTVPEVEIEGVVGDSIKT
CEVLNKNRFEAIYQTTTRDKNRIQLQKDLLQAHDSGVENLLVFTEDYRITGDSLQEMMFF
HVDAGKLESVLQHMREGRTVDGGELGKGADFVVGSGVESGWGKNIPDLEMKEMEAMAKIG
AGYFLSTPVFDVDGFEKFLKQVNTFGIPVIAEVMILRTAGMASFLNRHIKSGMVPEWVIK
KLAKAIDKEKASIEIFADTVKGLKDLCQGVHIITIGGEEKLRHYLDAAKLK
>A0A3M1A9J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MPKKNFLEELNQRVILFDGAMGTMLYNRGIFINQCFDNVNLVNPRLVKDIHTGYAEAGAD
VLQTNTFGANRFKLTKYGLQDSLEAINYQGAKLARDIAGKDLYVAGSIGPLGIKIEPWGK
LAKEEAREAFKEQAQALLNGGVDLFILETFSDLNEIEQAILAIKEICDLPIVAEMTIDEQ
GNSLYGTAPETYTHRLDNAGADVIGVNCSVGPPSMLNALEKMVKVTKKPIIVQPNAGNPR
VIDERNIYLATPEYFSKYATRFIKAGARLVGGCCGTTPEHIKEMAKSVRMLSPRKHSLIV
HVPKEVIHEVEPLPREKKSKFAAKISRGELVTSIEIPPPRGTDPSKILDSAKILKEFGVD
AINVPDGPRAMCRMGAQHLCIIIEQKVGIETILHYCCRDRNLLGMQSDIMGLYAVGLRNI
LIITGDPPKMGDYPDATAVYDVDSIGLTNMVNRMNHGVDLGGNKLDAPTAFHIGVGVNPG
ALDLEYEIRRFEWKVDAGAEFAITQPVFDPQVLLDFLEKIEHVRIPILAGIWPLVSYRNA
EFMNNEIPGISVPDEYMERMQKAQEISPEAAREEGIRIAQEAIIKLKGHVEGFEINAPFG
KIDSPIKVLSILKEFGGDV
>A0A662LVF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MRKTKTPSRLEKVLAAGHLAVTSECGPPRGSDPAVIIKKAEMIKDHVDAINVTDNQTAMT
RLCSLASVIHLKAMGLEPVLQMVVRDRNRIALQSDILGAASFDINNILCLSGDHQKFGDC
PDAQNVYDIDSMQLIRMARHMRDEGKFVGGDDINRPPRMFVGAAANPFADPFEIRVPRLA
KKIEAGAE
>A0A7K1GJA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myroides pelagicus|TrEMBL
MKVTEHIQRANGKTQFSFEILPPLKGQNIRGIFDAIEPLMEFKPPFIDVTYHREEYEYKE
AGNGLWEKRTVRKRPGTVGICSAIQNRFKVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKNETYFKAEAKGNKYASELVTQITELNQGIYLDPELENTSKTDFCVGVAGY
PEKHMEAPNFDTDLKYLKQKIENGAEYIVTQMFFDNSKFFEFVDKCRSIGIDVPIIPGLK
PLATLNQLNLLPQRFKVDLPDDLVAEVLKAKDNAAIREIGIEWCAQQSKELIVAGIPIVH
YYSMGKSDNIIQIIKKAI
>D9QV59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetohalobium arabaticum (strain ATCC 49924 / DSM 5501 / Z-7288)|TrEMBL
MAENSLEESITDKDDFTVTWELIPGRGARETNQEEIFTNAEKAAESDKVDGVTITENPGG
NPAISAEYLGMKVQELGIEPIVHFTCKDKNRNQIESFLYSLEREEVSNILVMTGDYPVGG
YKGASKPVYDLDPTQALDLITDLNEGLEYKDPFGRSVSLKETNFFPGAAVSPFKRLESEQ
MVQYYKLKKKIEKGAQFIIPQLGYDARKFHELIQFVEMNDWDVPVIGNLFVLPYGAGRAM
NANRIPGCVVTDDLLEQLKKEKEAEDNGKQARLMRAAKMYAFMKGMGYAGAHIGGHGLDY
EGVEFVIEKGEELAPNWRDYIHEFDFPMEDGFYYFEKDEETGLNTDQPAQRKSKPSKETA
HQLIRVGHNLLFEPDGLFFGPMQSICNVSEDGLLEEPFNFMERVIKTITNECEECGDCAL
VDLAYLCPMSQCPKNQRNGACGGSKDGWCEVYPEEQKCLYVRVYDRLKAYEEEEKLRDNW
VPPVDWDLTHNSPWRNYFLGRDHTAKEIGITSPGSEESKKA
>A0A484Q190|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|plant metagenome|TrEMBL
MDVAVARRPPLHDCYSMEVSAKDIPALTAVAPRLPPASTISIPYLAGEGNAARLAAARAV
RELGFEPMPHISARRVASLAELQAFVARAAAEAGVERCFVIAGDPSTPKGPFPDSFSLID
TGVFERAGIKALGVGGHPEGHPVMSVADRWEVLERKCRGIEGRGMAPSIVTQFVFDADVV
LTWLAALRARGIAHPVRVGVPGPAGVAVLARYAAMCGVGACASMLAKYGISIGKLLGTAG
PDRFVDRLAAGLTPAHGTVSLHFFPFGGIAQSVGWIEQYRATRKQNTR
>A0A329YWM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. AQ5-06|TrEMBL
MFPTRIEIIPSTGIVDQVQALVPLTTTLTMTCLPHHGIERTMRTSVELSGLGYTVIPHLA
ARSIQDRAELTRIMRECDGAGIVEVFVIGGDRKQPAGPYDSALPLLEDIAQYTGGRMRAG
VAGYPEGHPTVAALDLLDALQDKKHLATHVVTQMCFDAPKILDYTALLRREGVDLPVWAG
VAGSVPRTRLVALATQIGVGSSLKFLSSKGTLARKLLSGDRYSPHTLVAGLESQPGIAGI
HLYSFNNLDAVSNEAAASSTMALQPALIRGAAREH
>A0A4Z0Z2T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylaria hypoxylon|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTGMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
ATKSLELAEICQRELNLTTCLHLTCTNMSRKMIDNALEDAKALGIRNILALRGDPPRAAE
YQDANEDPENAIDEGFVWAIDLVKYVRNKYGDYFCIGVAAYPEGHADESHPLGQNLEHDL
PYLVEKTLAGADFLMTQLFFDTDAYGNFERKLREHPSGAFKSIPIIPGLMPIQSYQMIKR
TTKLSHARIPDRIMARLDAVKKDDEKVKNVGVDILCEIVEQVKEIQGRGQGPKGFHFYTL
NLEKAVSFIVERAHLISSTPEEEAVVDDEPLPNIPDLVINGTSSRDRHLQDISQSRRQST
VGSEPRNRVIVSERTLSNPEYEASQADVGIKASAINSRANTLAISEGEGVLGREATWDDY
PNGRWGDARSPAYGEIDGYGPTLHVTRAQAISLWGHPQSIEDVNTLFVRHLKGELNAIPW
SEEEVHEETGTITDQLIRLNQRGLWTVASQPAVNGFRSEDPTFWLGPSPWLHISKGVRRV
LYLRCRMAHPKRKVNKPRAGDFVSSDFPSAASPSGTAETTGADDNGYSMGESTTNAVTWG
VFPGKEILTPTIIEEVSFRAWSEEAFGIFSEWAQVYGKGHESEKLLEAARADSWIVNIIH
HDYMDKEALWDLLLK
>A0A1Z9BYH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium TMED102|TrEMBL
MRFIRDIHAEKQAAGKPTISFEFFPFKTPEGEATFFGKTLPALMAAKPDYASVTYGAGGS
TREKTLEIVEQIQTEFRLTTMAHLTCIKHTQAEIDAILDEARRRGIRNILALRGDPPPGE
DWSQTEGGFEFASELVTHMNGRGDFGVAVAGFPEGHIDCNEGREVDWQHLVRKIGCGADM
VITQMFFDNADYFRLADYLSEAGVKTPLFPGIIPVANAEQIKKFSAMCGAKLPEAFAARL
NELSADADAVGEYGIEYATEQCRELLDRGAPGLHFYTLNKSKAVLQILSNLGLN
>A0A1E7H676|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium S3730MH12|TrEMBL
MKTESNLEKVLAAGHLAVTSECGPPRGAVAKELTDKAKYLEGVVDAVNVTDNQTAMVRMS
SLAGSVLIKQQGMHPLLQVVTRDRNRLAIQADILGAYSLGIDTMLCLSGDHTKFGDHPMA
ANVHDIDSIQLIQMVKGMRDESKFQGGSDIKGAPKMFIGAAANPFADPFELRVMRLAKKI
AAGVDFIQTQCIFNIEKFELWMEGVRKMGLHKKCYILAGVTPMKSVGAARYMKNRVPGMD
VPADVVERMASVPKEKQPDEGVDICIETIERLKKVEGVAGFHIMAIEWEEKVEEIVRRAG
LYPRPEIS
>A0A545SA36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halothiobacillaceae bacterium|TrEMBL
MTQISCEFFPPKTEDGAAKLRATWQGLKAMQPAYFSVTYGAGGSTQERSFATVREIQQDS
GIEAAPHLSCIGSTHAQIRAILDDYRTQGIRRVVALRGDLPSGMGDPGELRYANELVEFI
RAETGDWFHIEVAAYPEIHPQAASARADLENFARKVRAGADAAITQYFYNPDAYFRFMDD
CERMGLGIPVVPGIMPITNYNQLARFSDACGAEIPRWLAKRLQAMGDDLEGIRAYGLDVV
GEMCEDLLAGGAPGLHFYTMNHVEPSMSLWKRLHQRPDMEM
>A0A2X3DH22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter fennelliae|TrEMBL
MLDSLITHIHSNKPFLSLEVTPNLGANLSSSLISELKDCTKAHAFVCTDSPLARLKPSSL
LSSLKLQNALGKPVICTLSMRDRNSIALSAEILAINELGVRAFLSLTGDPIKLGDCADSK
GVFESNSLKLAQIISQLNAGYALSGKPLDSAVQRIYNFSTISSYAQNPKTLESKIQKKIA
SGCEALFSQPVYSPESAEMLLQNIQRANASTGKSAQGKSAQLILGFFPVMSYKAALFLRD
KLPGVFIPDDWVERLQKASQIGKDEEHKVGLDLSLQLFKALQKIHNKIHFMSSNNFALFK
QFADI
>A0A5C1E4C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzomicrobium terrae|TrEMBL
MTTPTMTPATLPISIEFFPPQTPEGADKLRATRARLAALNPEFFSVTYGAGGSTQERTFA
IVREIQDEGFAAAPHLSCVGATRESIREILAGFRAQGIRRIVALRGDLPSGMASLGEFRY
ASDLVSFIRAETGSAAEGGFHLEVAAYPEVHPQAASFESDLAAFVTKARAGADSAITQFF
YNPDAYAHFVARVRDAGVEIPIVPGIMPIASFTKLSRFADQCGAEIPRWVRRQFEAYGDD
AEAVREFGLEVVTGLCRALIAQGAPGLHFYCLNQADLTLEIVRRLKA
>A0A4P6TKC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquitalea sp. USM4|TrEMBL
MNEQKKTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGHAAAPHLSCIGSTRENISAILNEYRNHGIRHIVALRGDMPSGMVAAGEFRYANELV
EFIRSEHGEHFHIEVAAYPEFHPQAKSAEDDLNNFVRKVKAGANSAMTQYFFNADAYFRF
VDEAQARGVDIPIVPGIMPIANFGQLCRFSDMCGAEVPRWLRQRMQSYYDDAASIRALGL
DVVTELCDRLLANGAPGLHFYTLNQAGLVSTVWQRLGL
>A0A6P0BEY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MALKNEARGRNDIRVSFEFFPPKSEEMEGQLWHAVSLLQDWDPDFVSVTYGAGGTTKAPT
LSTVTRFLSQTPLATASHLTCVGATKEETHQMVDTFRKAGVTHFVALRGDAPGGAGAPYQ
PHPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQ
FFFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFD
DKPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRRQTKSAGAA
A
>A0A7T6X9Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia pickettii|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRGILNTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGEAFHIEVAAYPEYHPQSRSARLDLENFARKVKAGADSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A6H2CBG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NEB149|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAADLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVEKVQAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNSSNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A7M3DXZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MVLKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSQLQDWDPDFVSVTYGAGGTTKAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPTFLDERFAGFDD
KPEERAKVASEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGISRREAKSAGAAA
>A0A1Q3QPU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriales bacterium 59-55|TrEMBL
MSDGAGGIEIKDKEKSSAINRLFSGGTVLCDGAMGTMLYARGVFINRCYDELNLSQPDLV
REVHAEYLQAGAEVIETNTFGANRYRLEHFGLQDKVREINLAGVKLARECVEHIREKQSS
TAFVAGSIGPMGVRLEPLGKVGLDEARAAFAEQIQALAEGGPGVGADLLIVETMTSLAEA
KQILLAARSEAPNLPVIVMMTVDEEGNCLDGASPETAAKKLTEWGADAVGCNCSAGPATV
LSVIERMRPATSLPLAAMPNAGIPRAVEGRTLYLTSPEYMASFTRKLVKAGASFVGGCCG
TTPSYTRAMKSSLRAMGAMNAGAQVIERADSGGTATIKNKVEPPPLAERSKIGSMIAAGK
FVSMVEIVPPKGIDCSKELNGAAELHKLGVDAINVPDSPRASARMSAQSLCVQIQQNVGI
ETILHYTCRDRNVLSIQSDLLGASSIGLKNILCLTGDPPKLGNYPDATAVFDVDAIGLVN
IVRNLNCGLDIGKNSIGESTGFTVAVAANPGIPDIDQEVRRFAYKVEAGAEYAITQPVFD
LRLLEAFLKRIEQFRVPVIAGIWPLTSLRNAEFMKNDLRVSMPEEIMARMAAVTSPEAAR
AEGVKIAQEMLAEARPMVQGVQVSAPFGKYAAAAQVLGLIEAEVA
>A0A6I5I2E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4913|TrEMBL
MTTLRDTLARPDPSFSFEFFPPKTEAGMYGLWQAIRRIERIAPDFVSVTYGAGGSSRDRT
IEVTKRIVAETTLRPVAHLTAVGHSVAQLRHIIGQYADAGVRDVLVLRGDPPGDPNAPWI
PHPDGFRHAHELVSLVRELGDFSIGVAAFPERHPRSPDWESDIRHFVAKCRAGADYALTQ
MFFHVEDYLRLRDRVAAAGCDIPIIPEIMPATDARQISRFAELSGAAFPEDLAHRLNAAR
DNPAHGYRIGVEYATAMAERLLAEGAPGLHYITLNRSTAAPEIHRAVTGSRSGRRVEMLH
R
>J9UTN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira pilosicoli B2904|TrEMBL
MNNNVENFIKKLENNNEYCFTLEISPQAKYDLSYIEKKINNSNIQNYVDAFVVTDSPFAN
IKISPILAAIQLQQKLNNNKPFIATQTMRDKNSIALQNDLIGANYFDIRMILAVTGDAIA
NGNQKQAKGVFEGNSNLLIDIIKNLNKSKSLGEFTFKEPLKPIYPFCVINSYAKNDDSLK
VRLAKKANSGVKAIFTQPIYEVERLEFLLKCIDELPLKEKPILVPGFFPVLTYKTAYFIY
YKLSGSYIPEKWLSKLKKASDKSEEEERKTATELSTKLFEDMLKIHKKMHIMSLNNYEFV
VDLLKNI
>A0A7C1B5C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon|TrEMBL
DEGIDLFILESFVYLDALLITINLIKKWTQIPIVAEVTIDNEENLLSGEHISEIVEPIEK
SGVVAWGFNCCKGARHILKLIDVVKEKAKLPLIAQPNAGFPRKIEGRKIYLCTPEYLAKH
ARYYVQKGVKIVGGCCGTTPEDIKAVVSAVRSLSPGRMMRIENIMRAVFDTTATSSVIPL
AERSSLAKKIANKRFVVSVELTPPKGPDPSKMLEKAKILKEMAVDVINIPDGPRATARMS
AQALAILIEKIGIETLLHVCCRDRNVIGLQADLLGSYALGLRNLLIITGDPPKLGDYPDA
TAVFDLDSIALVKLVQNLNRGLDLIGRPIHGATGFLVGVGVNPMALNLERELERFEKKVE
AGAEFAITQPIFDVKALERFVTQVRHLNIPIIAGIWPLRSYKAVMFMKKEVPGVIVPDEI
VKRMEKSPTGEAAIAEGIAIARETLEAVKDLVQGVQISAPLGKVEMVSKILET
>A0A7X2HQ02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia pickettii|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQH
EGIEAAPHLSCVGSSRESIRGILNTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGEAFHIEVAAYPEYHPQSRSARHDLENFARKVKAGADSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A135LBM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium patulum|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPIEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEAAENGFCYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNADVDQLIDHLKEKVDAGSSF
VVTQMFYDVDNFVEWLKKCRAKGITVPIIPGIMPIQTYASFIRRSNWTKVKVPDQWMEAL
EPVKNDDSAVRDIGKTLIANMCRQLIAAGIKHLHFYTMNLAQATQLVLKELDLSPSEESP
IQRALPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISNIFVDFLAGKLDRLPWSDSPITTEAHDIQEDLLK
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDELITRIEKND
DLTYHATNRKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGDHWS
KCHDAASPSRKLIQQVMDDWYLVNIVDNDFHRSNALFELFDGLEVKDLDVEVEMSEKPLT
NGHAEQNGVAAN
>A0A1Y0N9J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Curvibacter sp. AEP1-3|TrEMBL
MSTNQRIPLSLEFFPPKTPEGAEKLRTVRQQLYGLKPEFCSVTFGAGGSTQEGTFNTVRD
ILSEGVSAASHFSCVGATKSTVREQLATLKAMGVKRLMALRGDLPSGYGAGGEFHYASDL
VAFIRAETGDDFHIEVAAYPEVHPQAKSPASDLQAFATKVKAGANSAITQYFYNSDAYFR
FQEEVDALGITVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSYGDDVASIKAFG
LEVVTDLCEQLRAGGAPALHFYTMNQSAPTLALCKNLGLDA
>A0A0Q9A9V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Root264|TrEMBL
MALGTASTRTDHARTVRDMLATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPQGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSDAWEKDVAHFVD
KCRAGADYAITQMFFEPDSYLRLRDRVEAAGCVTPVIPEVLPVTSVKMLERLPQLSNAHF
PAALKERILTAKDDPSAVRSIGIDFATEFCARLLAEGVPGLHFITLNSSTATLEIYENLG
LHHPPQA
>A0A2E2AC64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospina sp|TrEMBL
MKISEKLSSSSPIFSFEFFPPKNSEGFATLYETIARLKSSAPGFVSVTYGAGGTTRSKTV
DLVGNIKNAIGIESMAHLTCVGHNEHEINSVLENLYEKNIENVLALRGDPPQGEEKFIKT
KGGFEYGNELVSFIKKNFSFCIGAACYPEGHIECKDLDTDIENLKRKVDSGVDFLVTQLF
FDNQNYFKFLDRVQAAKINIPVIPGIMPILNLKQMHRFTKMCGANLSPSLLDKFKGIEDD
NDKVREIGIAHAIKQCQELLEYKVPGIHFYTLNRSKATLDILDALRDFK
>A0A5N8Z552|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium AD-802-E10_MRT_200m|TrEMBL
MKFHEFYNNTGPVISFELFPPKTSKAVEDLKERLPQLISLQPSFITVTYGALGSTRERTL
EFASLLKNTYGIETAHHLTCVGSSKSTITTILEQLRANNIENIVALRGDPPHDGKEFISA
PDGYAHGDQLVSHIQDFGGFGIGVAGYPEKHLEAPDFATDLQNLKRKVENGADVIITQLY
YDNTHFYRFVDRCRKIGITQPIVPGLMPIFSTEQIIRITKMCGATIPKSLYKKLVASRDD
EENVREIGISHTTDQAIELLQHGVPGIHFYVLNRHFQIAEIMERIKFML
>A0A4R8YUN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT1-23-1|TrEMBL
MPDTSDPACGNIPFSFELYPPKSDAATSALHATIKRLAAAGPEFISVTYGANGSSRRSSL
DVLTHLLRTTTVDPLAHLTCVGSSNAEASRLIREFLDAGVRNFLALRGDPPEGTREGDAF
LGDLGSAAELVQLIHRVQAERVPYREAAIPGLPAARTIKREREKVRIAVAAFPNGHPRSR
STTQDIDTLLAKQAAGANLAITQLFFHADHYLGFIQRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRHATELARKLIAGGAPGLHLYAFNQHE
TVLAVLERCGLLTPTPAPSVSEFPASHPVKEYS
>A0A5K1I3K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas lysinitropha|TrEMBL
MSTQEHPLGISFEFFPPSTDAGRDKLVGVRDALASRAPRFFSVTFGAGGSTQDRTLNTVR
MVRESGFTTAPHLSCIGSDKGALRELLSRYREEGIDSLVALRGDLPSGMGGGGIGQLRYA
NELVEFIREETGDHFEIAVAAYPESHPQARNLEHDLANFASKMKAGADIAITQYFFSAEA
YFHFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIG
AFGEEVVSRLCQRLLDGGAPGLHFYTLNQAKPVLRILDNIIA
>A0A4R4Z5G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora elongata|TrEMBL
MDANAGQLEQYLMNARFEVLPLRGAVEQAELLPAGTTVTVTASPSKGTEATLDVAAQLVG
RGLRAVPHLAARLIADTAHLTALLDRADGLGLSEVFVVAGDSPQPRGDFPDALALLRAID
ELGRRPARVGITGYPERHAFISDASTIRAMAEKSRYADYVVSQICYDPHTVAAWVKAVRA
RGLALPIHIGVPGVVDAHRLLRISLKIGLGESMRFLRKQHGVVSKLLTRYTPEELLGELS
PHLADPDLGIAGCHFFTFNEIAKTLQWRHDLVARLREVPA
>A0A444I0M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MVSKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSQLQDWDPDFVSVTYGAGGTTKAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRPVAKSAGAAA
>A0A269PH41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium hadale|TrEMBL
MRGTFAPTRLSASAPIDRVGEDTTQQRRRTRTALSFELIPPRHGADEGKLDELIAGLAAY
RPDYVSVTSSRRSDWLTGTAALIARVAETTNLRPIAHLACTAGTREELVTWIRTLIDAGV
RGFLALRGDLPETGMPADHLQHATDLLNLIQDVEDEEAFRLAAGKLALSVACYPSGHAES
KNFDEDLDVLLSKQRLGADFAITQLFFNAQDYLDFVEVARLAGVRIPLIPGIMPMTSLKR
VQRMGELSGIEVPECVARTLAQATTPEEEYELGMQMSARLANTILDAGTGGLHVYTHNNL
AVTQDLLSRIGIPQRADHSPQ
>A0A257NW54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halothiobacillus sp. 20-54-6|TrEMBL
MIPIPLSCEFFPPKSDEGAAKLRAITTQLTASLKPEYFSVTFGAGGSTQARSFATVETIQ
TESGVPAAPHLSCIGSTRAGIAAILDQYRVLGIQRIVALRGDLPSGMRDPGDFRFASELV
TFIREHSGDWFHIEVAAYPEFHPQSLNAEADLRHFKHKVEAGANGAITQYFYSIEAYSRF
VDDCEKRRINIPIVPGIMPINNYTQLARFSDACGADLPRWLRKRLETFGEDMDGLRAFGH
DVVAKLTADLVTAGAPGLHFYTMNQADSIIAICRDAGVLPAGTQ
>A0A4U6CD13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquamicrobium sp. LC103|TrEMBL
MIEPRPPQTDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPEDVYE
RARVFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPVYQISCRDRNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDCMSLLEAVRTMRDERKFLSGRKLTTPPS
VFLGAAINPFAPPYDFRPLRLAKKIAAGAQFVQSQYCFDVPMFRDYMKRVRDLGLTEKCF
VLCGVGPLASAKTARWIRSNVPGIHIPDPVIARLEGAADQKAEGKRLCIDIINEVKEIEG
VSGIHVMAYRQEEYVAEIVHESGVLKGRKPWKREARADDAMVAERLGHILHDDTTERPQE
IVKAAAH
>A0A831LQJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariniphaga anaerophila|TrEMBL
MKVIDIIKNSGKTVFSFELLPPLKGNEATHLYKTIENLVDFDPKYINVTTHRDEVEFREM
PDGSIIKRTVRKRPGTVAIAASIQHRYGIPVVPHILCGGFTKSETEHVLIDLHFLGIENV
LALRGDGIKNQHVFQPEKEGHTYARELVEQIVNLKKGKYLEEDLKNNTPLDFCIGVAGYP
EKHFEAPNLQQDLFYLKQKVDAGAEYIVTQMFFDNRVYYDFVKKCREIGITVPIIPGIKP
INMKNQLTVLPKIFSIDLPPELAKELAKCKNNEYARRVGTEWAVYQSKDLVANNAPSLHI
YTYGISDNVKEIVKAVF
>A0A6I4Q7E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella sp. Pas-s95|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVPPKDDF
RYASELVTFIKENGDFNVIGACYPEGHLEASTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKAHDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVATLLAVPKTK
>A0A327YII5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus vitaminiphilus|TrEMBL
MGFLDDLAQQILIADGAMGTLLYSHGVDSCFEELNLSRQEEILHIHKAYIEAGANVIQTN
TYGANYVKLARYGLEEQVKEINEAAVRIAKQAAKGRAYVLGTIGGLRSIKKTAITLEEVK
RTFREQLYALLSEDVDGLLLETYYDLEELLTVLPIARKETDKPIVAHVTLHEVGVLQDGT
HLADAFDRLEALGADVIGLNCHLGPYYMIRSLEEVPLPKKAFLSVYPNASLPDYRDGRLV
YETNPSYFEETALAFREQGARLIGGCCGTTPKHIAAIAKALKGLKPVTEKKVKERNIVVS
VQASAPNKKPALHEIVKQRRSVIVELDPPKKLGIAKFLEGAKALKETGIDALTLADNSLA
TPRISNVALGTILKEQLGLRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAVTGDPSKI
GDFPGATSVYDLSSFDLIQLISQFNEGLSYSGKPLGEKTNFSIAAAFNPNVRYLDKAVER
LEKKIRCGAHYFISQPLYSERQIEEVYEATKHLSVPIYIGIMPLTSARNADFLHHEVPGI
TLSDEIRARMAACANDPIQSAREGIAIAKSLIDAAFELFNGIYLITPFLRYEMTVELANY
IYEKERASQERKIFNG
>A0A8H5R226|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sp. NRRL 25303|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLASDNSDHVNGSTEGGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLN
>A0A836ZWN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas vasicola pv. vasculorum NCPPB 890|TrEMBL
MPTRFAEPAAMTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAG
>A7HDS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeromyxobacter sp. (strain Fw109-5)|TrEMBL
MRISDLLRFARERGEPVFSFEFFPPKTDDGVRQLFETVEALRPLAPAYVSVTYGAGGSTR
QRTLELVKRLKRDTEVEAMAHLTCVGASREELAAVLDELAEAGIQNVLALRGDPPRGETS
FSPHPEGFRYASELVAFIRSRPERWRFCLGAAAYPEGHVETRDLAADLANLKLKVEAGAD
FLVTQLFFDNAQYFRFVERARAAGIALPIIPGIMPFTNVDQTERFTAMCGAAIPPRLRAA
MEVRREDPDSARDLGVAYATLQCAELLRGGAPGIHFYTLNRSTSTRAIVAALRASEPWRG
>A0A1Y3TI65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp. An76|TrEMBL
MKIIDRLREDSIHISFEVFPPKTDEGFDKVIAAVDAMAGLNPAFISVTYGAGGGTSKNTA
KIASHIKDDLHLLSLAHLTCASSTKEEVRRVIDDLKAHGIENILALRGDIPAGMAFPDAD
RFRYASELVEEIRKHGDFCIGAACYPEGHVENEHKEDDIRYLKQKVDCGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSATQMKRSQELSGTVFPRRFLAMLDRFGGSPA
AMKQAGIAYATDQIIDLLANGVKNIHIYTMNKPDVAAAIMGNLSEIIKA
>A0A1D2XC97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endozoicomonas sp.|TrEMBL
MTNESNSTPVSFEFFPTKTEEGAQKLEQHALTLAKYQPEFFSVTYGAGGSTRDRTLETVL
STQERTGIATAPHLSCVGDSKRELRQLLSFYQEKGIRRIVALRGDLPSGMGHGHGELRYA
NELVEFIRAETGDHFHIEVAAYPEVHPQAINMDKDLQNFKRKVEAGADSAITQYFFNADS
YFYFRDRVKAMGVEIPVVPGIMPITNYSRLARFSDACGAEMPRWIRKQLESYGDDITSIR
QFGEEVISNMCENLVAGEAPGLHFYTLNQAAPCEAICNNLGVAQL
>A0A1H6GA41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. YR583|TrEMBL
MTSNLNSLAEARRAAATPLFANLEGDIGVSFEFFPPKTEKMEAQLWDAFRTLEPLAPSFV
SVTYGAGGSTRERTHATVARIAVESKVPPAAHLTCVEASRAEIDEVAQAYWAAGVRHIVA
LRGDVPGGEPYRAHPDGYANAVELVAGLKAVAPFDISVAAYPEVHPDASCAEGDLDNLKR
KLDAGATRAITQFFFSPEAFLRFRDAAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PSWMVSLFDGLDDHPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVATEKDQAA
>A0A239ICZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas segetis|TrEMBL
MSQERRFSFEFFPTKTEAGHEKLMATARQLATYNPDFFSCTYGAGGSTRDRTVNTVLQLD
GEVKVSTAPHLSCVGDSKAELRELLDLYKSNGIKRIVALRGDLPSGMGMASGELRYANEL
VGFIREETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADSYFY
FVERVRKMGIEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIDSIQAFG
QQVITEMCEQLLQGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A2U1A0E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia silvatlantica|TrEMBL
MKPIELSFEFFPPKTPDGVEKLRATRAQLATLKPKFVSVTFGAGGSTQQGTLDTVVDIAK
EGVEAAPHLSCIGSSKEDLRAILGEYRSHGIRHIVALRGDLPSGMGAMGELRYASELVAF
IREETGDAFHIEVAAYPEYHPQARSPRHDLEAFAQKVKAGANSAITQYFFNADAYFRFVD
DAKKLGVEIPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRDSIRAFGLDV
VTDLCRRLVEAGVPGIHFYTLNAAPATKAICERLGF
>C4JM22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Uncinocarpus reesii (strain UAMH 1704)|TrEMBL
MEKISDKIAALPEDANFFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
ASKSLELAEICQRQLGLTTCLHLTCTNMNRALIDDALDEAKALGIRNILALRGDPPRSDE
YNLAGEDDSNKDFTYAIDLVRHIRRKHGDYFCIGVAAYPEGHADESHPEIQDPVRDLPYL
IDKTKAGADFIMTQLTYDIVAYKKFESMLRNHESGVFKTIPIIPGLMPIQSYSRLTRITK
LSHACVPPEILARIEKCKMDDEAVKRVGVDVVSELVDEIKTISCPGPRGLHFFTLNLEKS
VSFILERCNLIPSSSEPSSDTESESAVYAMHKNLTAPAGKAAFVSRRRASSLNSQPYNRV
IIDRADMSSQSSTTHETSAQGAGMPALNPPPRNTTLLISEGMGALGREATWDDFPNGRWG
DARSPAFGEIDGYGPSLHVTANVARRLWGFPTSREDINQIFRRHVSGALHAVPWSEGGAA
EESGGLNPETATIRPYLLDLIDKRGWWTLASQPAVNGVRSDDTTFGWGPPGEGFVFQKAF
VEFFCSSNDYRSYLKPLLQRYGHDEFAWFATNAAGDFEASTPPSAHSPTEPVDAGFEDPS
SPAASNPGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWDEWRRIFARGSPTEK
LLAQTKEDVWLVCVVGQRFGAGGEPGKDATDEGKLLWKILAGENVALES
>A0A5D0MWU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. AP08|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRHVIGRLASVGVRNVLAVR
GDPPGNPGGEWIEHPEGVRYAEELVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQLATIERSVQLSGAPF
PPALAERFAEVADDPEAVRRLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWQRLR
ADARV
>A0A7V1IKI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MAIADLYQRSEPVLSFEFFPPKTDAGYRSLFRTIEDLKKLSPGFVSVTMGAGGSTRTKTV
DLTIEITREIGLVTMCHLPCTGFRREEIGTILDQLEEGDVHDVLALRGDPPRDDPDFVSP
EGGFRHANELVEYISARGGFSIGAACCPEVHPEAPDAETDLINLKRKVDAGTDFLISQLF
FDNDRFFDFLERARAIGIHIPIIPGIMPIATVPGIRRMAGMTGTSFPPELEAELRRVEGD
DEATYELGVRWATRQCEGLLAAGVDGIHFYTLNRSPATREIARNLFDR
>A0A7V1EG75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKAGSNLEKILSKGLFAVTGELGPPKGNDVSVVKRKADLLKGYVDAVNVTDNQTAIVRMS
SIATSSLLIQMGIEPVMQMTTRDRNRIAIQSDIFGATALGIKNMLCLTGDHHTFGNQVDS
KNVHDLDSIQLIDCVRTMRDEGTLLGGEEKIEGKIQLFIGAAENPFADPFEFRVVRLAKK
VRAGVDFIQTQCIYDMKRFKEWMKMVRDRGLHEKVHILAGVTPLKSGGMARYMAKNVSGI
IIPEEIIDRIVKAKKPAEEGIKLCVEQIQELREIEGVHGVHIMAIEWEQMVSQITEMAGL
LPRPKVE
>A0A7C5FHS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MALSLLEEKLEAGEFVVTAEVGPPKGTDLTEMIHNIDLLKEWVDAINVTDHQSSVMRFPS
LGGCLLVKERGGEPILQVTCRDRNRLALQADLLFAYTRGIRNVLCLTGDSVEVGDHRGAK
PVFDLDSVQLLRGIKEMEEGRDMGGNPLKGAPQFYLGASVHVEADEIEPQLMKFEKKVMA
GARFFQTQGIFRVESLRRFMPYASQFGVKVLAGIIVISSARMARYMNEKVPGITVPDEII
EELSSTEKGKALQKGIEIAARTIRTIKEEGLCSGVHIMAIGNEKVVPELIEAAGLNGRAR
>A0A147GD20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas parafulva|TrEMBL
MSVLKTALQQQQFACVMEFVPKPSAERFAAMDAIMARRQLCGWPMTLAIGDRVSSPLDMS
PLDALACFEHPVPALPHFSGKDRERHHLLAQMRRMDAAGQHQLLLLTGDRLPGHTPGKRP
VRYLESVAALQIARQTYPHWWLGAALNPFKYREEEGAAQYLKAEKKLAAGADFFILQLGF
DAAKHQEAMHWMRRQRAHKPMLACLMSLTQGRAGMLDHVAGVTVTPSMRQMLEAEAAQSK
AFAQARSIDRLALQVIGVKLMGYAGVHLSGIHEPSQLLALEARLAHWQTQVATLEQWTPA
WQASWQMPGLPAVTFHPPQAAWREGESRVVASFAQKARYHAMHGMHGLLFSRRNPVSQLF
GWAVRQPMWTTGLGAQVLHSVERAVKRPLLGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTTLNRCEFGDRECIHSAKYRTAKAVQQTDVLAQRLIPCVEQHTRHRSSWPGWFGGKAQ
PVTQPSAPRSRRES
>A0A373VZX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. AF17-7|TrEMBL
MNIADLFEEGKTIFSFEVFPPKKESGIETVYDTIEKLTDLKPDFISVTYGAGGSGVTNPI
TKDICSKIKNEYKLETIAHLSCINNTKDEIDKILEELKKEGIDNILALRGDRVEGLEPKK
DFTYASDLTKYIMDKGGFHVSGACYPEVHMEAKDAVDDIKNLKKKVDAGADHLISQLFFD
NRVFYDFLERARIADINVPIEAGIMPVTSKSQIERMVTMCGASIPASLSRIMQRYESNPE
ALRDAGIAYAINQIIDLAANGVDGVHIYTMNNPYVARKITEGVESVVKHNR
>A0A7V4EAN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNDYKSQSRLERVLKAGYFAVTGECGPPRGADPEAIRKKGELLIGCVDAVNVTDCQTAVV
RMSSLASCLILKEMGFDPILQMVTRDRNRIAIQSDVLGAAALGINNILCLTGDHQKAGDH
PQAKNVFDLDSIQMVQAIKRMRDEGRFINGEELTVRPRLFIGAAENPFADPFEIRHLRLA
KKVAAGADFIQTQCIFNVKRFREWMKRVVDLGLHEKVYILAGITPLKSVGMARYMKTQVP
GMDVPDELIERLKGVPKEKQGEEGIKIAIEIIQEIREIEGVHGVHIMAIEWEEKVKEIVE
GAGLLPRPQI
>A0A7V3KZZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKAGSKLEKILTSGGFAVTGELGPPKGADVSVIERKANLLRDNVDAINVTDNQTAIVRMS
SIAVGAILQRMGLEATMQMVCRDRNRIAMQSDIFGAYALGIRNILCLTGDHQKFGNHPTA
KNVFDLDSIQLIQMVRRMRDEHKVLGGDEIEGVPAMFIGAAENPFADPFAYRVIRLAKKV
AAGADFIQTQCIYDLEKFARFMEMVRDRGLDEKVHILAGVTPLKSVGMARYMKEKVAGME
IPDEIINRLKGVGKDKVREEGIKICVEQIQRLREIKGVHGIHLMAIEWEEVVHEIVERAG
LLPRPEV
>A0A7W0VU45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
AAVAIARDVAGDRAYVAGAVGPSGARFGIATAAERRNARFALAEQVDVLVLAGVDVIMLE
TFTSILEMELALEVARERGGSRMPVIAMMVFDAHGKAEGGLSPNEVADRMIAAGADVVGG
NCGIGPAELYQVTTGMVGRGRPVIAQPNAGLPASVEGRTLYVANPEHFGVFARRMLKGGV
RLVGGCCGTTPDHTRAMLGSVRMLRGESLERPGSERAPGANVSITTAPAPAPAAKVPLAE
RSKLGERLVAGEFAVSVEITAPAGSDLTKTKQQVADLLAGGVDIVNIADGPRASARMANV
AVCARLARETAVEPILHVCARDRSFLGIIAHLLGAQGLGLRNLVIITGDPPKMGDYPFST
PVYDVDSVGLLRIASGLNAGVDPAGKECEPTSFVLATGAEPAAHDRERELRRLEEKKHAG
AELIMTQPVYDPRTLERFLDDVKPLGLPVMVGILPLASHRNAEFLHNEVPGMGIPAEYRE
RMAKVGGGPAARAVGIQIAQEALAAVKHRVQGAYIMPPFNRVDSALSVLEVARDRMKR
>A0A7C4DJT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIDRLLGLGVPSISFEFFPPKTEQGFASLYQTIDELRPHKPTYVSVTYGAGGSTRQKTV
DLVSRIQHGLGIRSMAHLTCVGHTADEIGQILDQLWEARIRNVLALRGDPPGGQSQFVAT
EGGFSHANELTAFVRARHDFCIGVAGYPEGHPQCLNRIRDLEHLKHKVDAGANLVITQLF
FDNADFYRWRDLARAMGIKAPLVAGIMPITNVAQIKRFVSMCGAKLPHNLLLRIEAVESS
PEAVHAVGVEYAIHQCQDLLANGVDGLHFYTLNKSKATVEVCKALGARHVS
>A0A509LPC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTSLFLNNDEFTITIEVVPPTGNDPATILKKLTSISDLSFHGFSVASNPVAKPKMSAMVF
THLIQKATQKPAILHCTVRDHNRLGLQSELWGAKALGIDTVISVTGDPSAFRAEEPTSTV
GDLNVCQLISMARDSDLFTGAVLDFRPEFNGLEHETKRLAKKVASGCRFIVTQPIYDEET
AKEIHEAVKHLNVPVIMGILPLLSYKHALFLHDKVAGIAVPEPLRKRMEEAQDPAKEGVS
QARQMLELAKKMFSGACIMPPFDRFEILPDILKS
>S7TMC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfococcus multivorans DSM 2059|TrEMBL
MSKESRTPSKLEKILAAGHFGVTSECGPPRGSDPEAISEKAALIRNHVDAVNITDNQTSV
CRMCSLAACIRLKTLGVEPVLQMVTRDRNRIALQSDILGAASWDINNILCLSGDHQSFGD
HAKGQNVHDLDSMQLLQTVRLMRDEGKFLGGDEIKRPPKMFVGAAANPFADPYEIRVSRL
AKKVAAGAEFIQTQCIYNMEKFEDWMKQIVDRGLHEKVYIMAGLTPMKSVGMARYMKNRV
PGMDVPDAIVKRLADTPKEKQAEEGIKICIEQIQRLKEVKGVAGFHIMAIEWEEKVPEIV
EAAGLYPRPEV
>A0A535B992|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSHLRERLEAGKFVITTEMEPPKGTDLSQFLSTAALLKDKVHAVNVTDNQRAIMRLSSVG
GSALLIREGLEPILQVTCRDRNRLALQSDLLTAWVLGVRNVLAMTGDPVEAGDHPMAKPV
FDVGSAALLQLIAQLNVGKDGGGHPLEGRTDFFCGATVNPCVVPLEPELKRFQEKVEAGA
RFFQTQAIYDIEAFARFMEIARKLPVYILAGLIPLRSARMAQFLNEKVPGIHVPAAMIER
LDKTSDPVESGLAIAVELVEGLKELCQGIHLMVVGKEKDFEILRRISVLKAGVHEHRDSH
R
>A0A661NLN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRVIDLWSEKKKPTVSFELYPARDPAAAEKLDKVIDRLAKLEPDFVSVTFGAGGSTREGS
YALVKKLKQEKGLEVVAYFTCWGLGPEQISAVLDDYRELGVETILAARGDPPHDQPGFQP
HPESLAHASDLIAFIKPRYDFCIACAGYPEGHVEAASPEKDLEYLKLKVDRGADFVITNY
TYDNDLFFAFQKRARALGIEMPILPGVMPIYSVKMMENLARLCGASIPDRVRKDLESLDP
ADKKAVAAYGIDLACDLWRGLLRGGAPGIHIYTMDRSKAAVQIVTTLRDEGLL
>A0A661PXT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
VLPKLFSISLPQDLADELAKCKNNDDAKIVGTEWAIQQSKDLVAHNVPSLHIYTYGVSDN
TRKIIKAVF
>A0A661T8F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNSGSNLKKILEAGHFAFTGELGPPRGADVEAVRKKAAFLKGNVDSVNITDNQTAMVRMS
SWAASLIAIQEGLEPNYQMVCRDRNRLAMQADILGAYAHGIHNILCLSGDHQQFGDHPHS
KGVFDIDSIQLIGMVKKMRDEGKFLGGADIDTPPKMFIGAAANPFADPFEWRVYRLAKKI
AAGADFIQTQCIYNMEKMRTWISQANDMGLTEKVYILAGITPMKSIGMARYMKSKVPGMD
VPDEIIKRLQGVDKKKVADEGIKIACEQIEEFKEMKGVAGVHLMAIEWEHKVPEIAERAK
VLPRPQVD
>A0A259SK14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. 13-71-7|TrEMBL
MAARALVDDFSLEMTGKDVPALQEARDTIPARTKINVTFLGNEDLEMRVAAAKAVRDLGF
VPVPHISARRLRSRAQLEEFLGRLQEAGATDHVFVVGGDPATPDGPYASAFDVIYTGLLL
DYGVREVSIAGYPEGHPDIGDDELWRHLESKSAVLTEQGLDAVILSQFAFDTDPVLAWID
QVRARGIASEIRVGTPGPAGVKRLLGFARRFGIGANAMIVKKYGFSLTNLMGTAGPDAFV
SDLSARLAADAGTGAVKLHFYTFGGLFATSAWARDFVAARD
>A0A1C5WK24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Flavonifractor sp|TrEMBL
MKLAELFGKGRTVFSCEVFPPKKTSPVDSIYKTLDGLRDIHPDFISVTFGAGGSQVNQST
REIAGLIQNQYHIPAMAHLTCVAAGREDVDRLLEELKAEGVENILALRGDVNPDIPPKTD
FAHASDLVSYIRAHSDFGVSAACYPEGHLESPDLVSDIRHLKEKVDAGAQHLVSQLFFDN
EDFFRFLERARIAGIDVPIEAGIMPVLSRSSIQRMVSMCGASLPSKLTRILARYGDHPAA
LREAGIAYAIDQISDLIAGGVEGIHLYTMNDPAVAQQIAGSLTSIRSV
>A0A259EQQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. 17-46-58|TrEMBL
MELSVEFFPPKTPEGESKLHVVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
TETGDWFHIDVAAYPETHPQAKSPATDVDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YDLGVTQPVIAGIMPITNSTQLLRFSDA
>A0A1C6C3F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Flavonifractor sp|TrEMBL
MKLAELFGKGRTVFSCEVFPPKKTSPVDSIYKTLDGLRDIHPDFISVTFGAGGSQVNQST
REIAGLIQNQYHIPAMAHLTCVAAGREDVDRLLEELKAEGVENILALRGDVNPDIPPKTD
FAHASDLVSYIRAHSGFGVSAACYPEGHLESPDLVSDIRHLKEKVDAGAQHLVSQLFFDN
EDFFRFLERARIAGIDVPIEAGIMPVLSRSSIQRMVSMCGASLPSKLTRILARYGDHPAA
LREAGIAYAIDQISDLIAGGVEGIHLYTMNDPAVAQQIAGSLTSIRSV
>A0A661QEE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MASKFRKALESGKFVVTCEIAPPKGTNLKKMLHHVELLKDKVDAINITDHQSSVMRFPSL
GGALLVKESGGEPILQMTCRDRNRLALQADLLFAYTRGVNNVLCLTGDSVIFGDHKEAKG
VFDLDSSQLIMAIRKMEKGKDLGGNDLDGEMEFCVGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVYDLDNFKKFMEYASQFPVKVLAGIILLTSAPMARFMNKNVAGVSVPQNLID
EMASAPKGKAIDKGIEIAGRMVRRIYEEKMCHGVHIMAIGREELVPEIMAAAGLI
>A0A1M7L104|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerosporobacter mobilis DSM 15930|TrEMBL
MKIKDILNKKQPTLSFEVFPPKKDSDYMKVEEATIKIAKLKPAFMSVTYGAGGGTSKHTV
DIAAKLYNSCGVTPLAHLTCASSTKEEVANQLGKLKEQGIENILALRGDRVAGREIAGGE
EYQYASELVQVIRSYGDFCIGAACYPEGHVEAANRKEDIVYLKEKVDAGCDFLTTQMFFD
NNILYNYLYQLREAGITVPVIAGIMPVTNPGQIKRICELSGTVLPQRFKAIVEKFGDNKE
AMEQAGIAYATDQIIDLYANGVNAVHVYSMNKPEVASSIYHNISKIIG
>A0A523IIB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIAELYERGRPVFSFEFFPPKTDGGVRQLFRTLDDLRRLEPDFVSVTYPLDRSRRHMTV
EIVSRIQREIGIEAMAHLTCVDASRDELRDALKWLDAEGIENVLALRGDPPSEQETAIPR
GEWFPHASDLAEYIRQRFGFCIGGAAHPEKHPEAPDFETDLENLRRKVQAGCTFLITQLF
FTNSDYFELVERARALEIEVPIVPGIMPVTSVSGIKRMAKLNGSAMPKDFLAELERVQDD
ELSVEELGVAYARSQCRELLEKGAPGIHFYTLNRSPATRKVLSYLRGEACTR
>A0A534PAE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRITDMLRFAAERGEPVFSFEFFPPKNDSGVNSLFETLRALRPLAPSFVSVTWGAGGSTR
GRTLEMVTRIKRETEIEAMAHLTCVGASRHDLEEQLAVICDAGITNVLALRGDPPRGQRE
FIPHPEGLAHASDLIQIAREVSEKRGVKLCIGG
>A0A661RVQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSANGLKSGSNLEKILKAGHFAFTGECGPPKGANVEHLREKYAHLRGVVDAINVTDNQTA
VVRLSSMASCALMVADGLEPNFQMVCRDRNRLAMMADIFGAYALGIRNMLCLSGDHQHFG
NHPQAKNVFDIDSMQLIALVRKLRDEGKFPNGDEVDGPPRMFIGAACNPFGDPTEFRVHR
LANKVDAGVDFVQTQCIYNMERFRQFMRQAVDMGLAERCYILAGVTPMKSARMAKYMAKF
VPGMDVPEALIKRLEGAEKGKQAEEGIAAAIEQIQEFKEMPGVAGVHLMAIEWEHKVPEI
AQRAGVLPRPEV
>A0A5D0S9N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceaniovalibus sp. ACAM 378|TrEMBL
MTTPNVSFEFFPPQSLEASFRLWDTANILAPLNPGFVSVTYGAGGTTRTLTHEAVGLLHK
NYGLTVAAHLTCVDASREETLAIAQSYKDAGVSQIVALRGDPPKGSGTFTAHPEGFVSSV
DLISALAETGDFEIRVGAYPDRHPEAANDTADVDFLKRKIDAGATSAITQFFFEADTFLR
FRDACAAAGIEAPIIPGILPIENWGGVKRFAARCGTSVPQWLDDAFTTAVRDGREELLAT
AICTELCSGLLNEGVNDLHFYTLNKPHLTRNVCHALGVTPHVGLEKVA
>A0A0S8C8X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium SG8_51_3|TrEMBL
MKAGTKLERILTGGKFAVTAEAGPPKGTSAEAVRKKGELLRHCCDAVNVTDNQTAIVRMS
SVAGCLILKQQGIEPVMQMVVRDRNRLALQGDVLGAVALGIGNILCLSGDHQKFGNHPGA
KGVFDIDSIQLLQALKMMRDEKKFISGEDVSGEVPVFIGAAANPFADPFEYRVNRLAKKI
KAGADFIQTQAIYDVPRFAQWMAMLTERGLDKQVHIMAGVIPIRSAGMARYMRDYVPGVA
VPDEIVTRMEKSEAPKEEGVKIILEIIEKLKEMPGVHGIHIMAVGWEDIVPEVVQKSGLM
PRPVV
>A0A496Y898|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MASRFKDALESGKFVVTSEVAPPKGTNLEKMKHHVDLLKDKVDGMNVTDHQSSVMRFPSL
GGALLVKEMGGEPILQMTCRDRNRLALQADLLFASNRGINNVLCLTGDSVILGDHKEAKS
VFDLDSSQLLATVRQLEKGRDLGGSDLDGAVSFCAGAIVTPEANPLEPQLIKFEKKVEAG
AEFIQTQAVYDLDHFKQFMEYARQFPVKVLAGIILLTSAPMARFMNKNVAGVTVPKELID
EMAAAPKGRAVDTGIMIAGRMIKRIRDEKMCDGVHIMAIGREELVPAIMEAGELL
>S7TNZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfococcus multivorans DSM 2059|TrEMBL
MKSGSNLEKVLRAGHFAFTGELGPPRGANADAVREKARYLKGLVDSVNITDNQTAMVRMS
SWAASLIAIEEGLEPNYQMVCRDRNRLAMQADVLGASAHGIRNLLCLSGDHQQFGDHPNA
KGVFDIDSTQLISTIKKMRDESKFLSGAKIDGAPKIFIGAAANPFAEPFEWRVHRLAKKI
EAGADFIQTQCIYNMKKMREWVKMANDMGLTEKVAILAGVTPMKSLGMARYMKNNVPGMD
VPDEIIDRLKGCAKGKHAEEGIKMACEQIEEFKEMKGIAGVHLMAIEWEHKVPEIAERAG
VLPRPTFNEEPAE
>A0A661LG80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSNLERLLEKGEFVVTGELGPPKGTDVDVVKKKASMLKGNVDAVNITDNQTAIVRMS
SIAAAKVLIDEGLEPNMQMVARDRNRIAMMSDLFGANALGIRNMLCLSGDHQTFGNHPEA
KNVFDIDSIQMIYMVKTMRDEHKVICGDEIEGDFKMFIGAACNPFADPFRYRVHRLAKKV
EAGVDFIQTQCIYDMKRFKEFMKQVVDMGLHEKCKILAGVTPLKSVGMARYMAANVSGII
IPEEMIARLKGAGKGNVATEGIKILCEQMQELKETEGIAGIHLMAIEWEHRVPEIMEMAG
FLPRPKP
>A0A4Q4L749|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas koreensis|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETADHFHIEVAAYPEMHPQARNYEDDLANFVRKAKAGADSAITQYFFNADSYFY
FVDRLQALGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTLSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A7W1IBX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MAGAQPRVWEAGVKTLRDLIADGRVHVADGAMGTVLYGRGVFLNVCYDELNLRQPDLVRE
IHREYVRAGAEIIETNTFGANPLKLAGAGLAGETERINTAAATLALEASGQRAAVVGAIG
PLGVRLEPFGEMSAGEAQMAFSRQVQGLLAGGVSGFILETFSDVNEIRAAIAAVRALCDL
PIIAQMTVGTDGRTHYGTAPLVFGPELEAMGADVIGVNCAVGPHGVLEAIEQLAGATGRP
LSAQPNAGLPREVGDRKIYMASPEYMASYARRMVEAGARFVGGCCGTTPEHIKAIVGFVQ
SVSPRHAFTVSETALPAVAREPVPLAERSKLGAKLAAGRFVTTVEIVPPKGVNPAPMFEQ
VRQLKAAGVDAVNVPDGPRAQSRMGALLSALMIEREVGLEAVVHYACRDRNLLGMLSDLL
GAAAAGVHNLLLVTGDPPKMGPYPDATAVFDIDSIGLTNLVSRLNRGLDPGGNAIGEPTR
FVVGVGVNPAAPDFERELSRFRWKVDAGAEFAITQPVFDLDQFDRFLDRLGETRIPVIAG
IWPLVSLRNAEFLANEVPGITVPDGVLERMRRASAGGKEEALAEGVRISQEMLVALAERV
QGAQVSAPLGRVSVALDVLDSVRIEPAGGPRYTPAR
>A0A1H5SBL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryocella elongata|TrEMBL
MKTSSSPIEIERLFTSQTVLCDGAMGTMLYSCGVFINRCYDELNVTQPDLVRSVHQQYLQ
AGAEVIETNTFGANVFRLAHYGLSDKVHAFNLAGAKIARQCVDAIHEKQGTKAWVAGAIG
SLGVKLAPEGEVTADEARAAFAEQIKALAEGGVDLLIAETMMSVAEAEQAILAAREVAPQ
LKIVVLMTAGEDDNCLDGTSPEDAARRLTAAGADAIGCNCSTGPITVLEVIQRMRPVTNL
PLVAMPNAGMPRQVEGRHIYMTSPEYMARNARKLVSAGAAWVGGCCGTTPAHIRAIRSEL
RAMTAQAVGEASVGSSAVAGVARSEEVSVEPPALEERSLIGRKIARGEFVTMVEIVPPRG
FDPSKELAGAALLARAGVDAINVPDSPRASARMSAASLCLQIQQKVGIETILHYTCRDRN
ILGIQGDLLGAASSGLKNILCLTGDPPKMGNYPDATAVFDVDAIGLVRIVQGLNHGLDIG
RGPIGGSTGFTIAAAANPGVPDIDHEVRRFAAKVEAGAEYCITQPVFDLRLLETFLRRIE
GFRIPVIAGIWPLTSLRNAEFMKNDLKVAMPDEIMERMATAKNKEAGLAEGLAIAREMLA
AVRDEVQGTQVSAPFGKFGAAVEVLGLAVSQSAEVA
>A0A6S6FYS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. HMP6|TrEMBL
MTVSVKQMEEARHALATPLFADLAGDARVSFEFFPPKTEKMEETLWASVQTLSPLGPRFV
SVTYGAGGTTRERTHATVARIARETDIPAAAHLTCVAATRDEIDAVADAYWQAGVRHIVA
LRGDSPVPGEKFHSPVGGYANAVELVEGLRKLHPFEISVSAYPECHPDSVDAAADIDNLK
RKLDAGATRAITQFFHEAETFFRFRDAATKAGVTAEIVPGIMPIMNFGAVQRMSAMCGTV
VPPWMGTLFEGLDDHPAARQLVSATIAAELCRRLYAGGVRDLHFYTLNRAELSFAICHLL
GVRAKAPVPAVKAEAA
>A0A645FAA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MGAACYPEGHPEAGNRAADLAHLRQKVDAGVDFLTTQMFFDNATLYNFMYRALNAGITVP
IGAGVMPVVNAKQIKRIAALSGATLPARFWSIVDRFGDDPASMRQAGVAYATEQIIDLIA
NGVNNIHLYTMNRVDVAQDVFRNLGAILAR
>G2T1G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia hominis (strain DSM 16839 / JCM 17582 / NCIMB 14029 / A2-183)|TrEMBL
MRLTELLKTDQVTISCELFPPKQGAQLANYKNIVADMAALKPAYMSVTYGATGGTSDYTV
ELASEVEKHQIPALAHLTCASSTKEKVASVIEELKEKQISNILALRGDIPQNADFPLPNQ
YRHASELIADIKAQGDFCIGGACYPEGHPEADTIFEDLDHLKEKVDAGCEFLTTQMFFDN
HILYNFLYKALSRGIDVPVVAGIMPVTNKAQIKRIVSLSGNMVPPRFLAIVDRFGDNPAA
MRQAGIAYATDQIIDLIANGVNHVHIYTMNKPDVAGEILDNLSEIYVRA
>A0A1G8MZ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natribacillus halophilus|TrEMBL
MMEMMDRQSASELIGQMSEPRFELIPANRIVERTTAALPPYATLTITCSPKKGVDATIET
AVALAPQFARVVPHIGARMIRSEEHLETMLDKLRDHGIDEIFVVGSDQDQPLGPYRDGLE
LLQSLAARDHGLRRIGIPAYPEGQPKIDNDILTKDLQAKAPLADYAVTQMCFDSGQVLSW
LREQREAGLQLPFYLGIPGPVKPDKLLRIAASIGVTDSLRFLRKNLKLSGKLLHGYDASD
LMNAYTPHLNDPDYGIAGFHIYTFNELVTLKKYYERLAM
>A0A542I9V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. SLBN-83|TrEMBL
MSPPSLIDAHPNLSDAAPVALSYELFPPRSPAAAETLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNSPEELAAIVGELLDTGVRGILALRGDLPKD
ASAPAAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPARHPESPSEEHDVEVLL
AKQRSGADFAITQVFFETRHYADLLTRARRAGVTIPIIPGVMPLTSLRRLNRLGQLTGVE
PAPELMAKLAAADTDLERLHIGVDATVELANAALDAGAPGLHIYTFNEHQSALEVLDKLN
LPRRSRPGNQHSRRESVARIQLAS
>A0A520S784|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoricolaceae bacterium|TrEMBL
VEGLLTKHPFELFVAAYPETHPQAISADTDLDNLKRKVDAGGHRAITQFFFDNAIFLRFR
DRVAAANINVELIPGILPVTNFNTLVRFADACGASIPATLKTLFEGLDEDPSTRQLIAAH
AAVSQAEDLGREGVNDFHFYTLNRADLSFAVCHALGVRGNA
>A0A0V0TPZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella murrelli|TrEMBL
MHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSKIVIPDSVLTTLESIKENAEA
VRNFGISYAVQLCRKLLNREHHVVPGLHFYTLNQEKSILEQIGFWKKAPVRMFPWKKHTV
HSVRCREAVRPIYWTARPKSYLCRTRDWKQFPHSRWGDVGNPAFGDLKHYLFSCIDQMDD
SCALDMWDKELSTLEHVRDIFCNFIARTPNRHGHSVRRLPWNENHLDPAADVLKNELIYY
NSNGILTINCQAAVNGLPSSDPIFGWGEANGYIYQKGYLEFFASSTCTTILLNHVQNFPS
INYHAINFDGSFETFNYDEDATVALTWGVFVGQEIVQPTVANAASFRVWKVVAQLSFIQL
FLFVFEQDEAFDLWQRWAGLYESGSIGRKLLQRIHDDYRLITLIDNDYPQPCSLSALLRA
VISDYIGGKNLTTDDDRLACKKKQCVRECVRACAYVENSGRLALRASKHGITAEKEEEEE
EEAIIE
>A0A3S2HF43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.06.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>W3XEC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pestalotiopsis fici (strain W106-1 / CGMCC3.15140)|TrEMBL
MHIKEMLADAERSGQPSFSFEYFPPRTAQGVQNLYDRMERMYEFGPKFIDVTWGAGGRIA
ELTCEMVAQAQTYFGLETCMHLTCTDMGEEKVNNALQNAYKAGCTNILALRGDPPREKEE
WVATEGGFQYARDLVKHIRNKYGSHFDIGVAGYPEGCDDNKDEELLLDHLKEKVDEGATF
IVTQMFYDVDNFVRWVGKVRERGITIPIVPGIMPIATYASFIRRANHMKCKIPEHFTKAL
EPVKNDDAAVREVGKKLVADMCRQILGAGICHLHFYTMNLAQATRMVLEELDWMPTQGRP
RKHALPWKQSLGLGRRDEDVRPAFWRNRNKSYVARTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKSVRDIADLFVRYLENDLDSLPWSEAPITSEADSIKADLIE
LNRRGLLTINSQPAVNGAKSNHPIHGWGPPGGYVYQKSYLELLVSPELFQKILPRLHEHP
DMSYYAVTRTGAVKSNASSEGPNAVTWGVFPGKEIVQPTIVEGISFLAWKDEAFRLGSDW
ARCHDAGSPSRELIDKITNEWYLVNIVNNDFHQPRTIFELFDGLSVDGLEDEVIVPPKVT
NGVTAEPLD
>A0A316UX67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jaminaea rosea|TrEMBL
MTTMNGSEDWRITSKIAQAEKEGRTWWSFEYFPPRTPQGLANLYDRCQRMSELGPAFVDI
TMHAGGRTLDLTNDLVKIVQSYIGIETCMHLTCTNMPREKIDRALELAKEAGCRNILALR
GDPPAGQHEWEPHAAGFTYAKELIAYIKEHYGDYFSIAVAGFPEGHPEAKEGRDVELKHL
KEKLDAGADFIFTQMFYNYDIFAEWMKDIRAAGITCPVVPGVMPIQTYSGFQRATERFGT
LVPQYFHDALTPIRDDDEMVRKVGTQLVGDLCKKIIDPNNGLGISGLHIYTMNLERGSRM
LLEYLELGPTPQQVKSLPWTPSLTPKRRDEGIRPIFWANRARSYVSRTETWDEFPNGRWG
DARSPAYGDVDAYGVKLRYSNEEALKMWGEPTTLDEVKDLFRRFCAGEVKALPWSETGVA
KETTKIDEQLARLNSLGYFTINSQPAVDGVRSEDEIHGWGPKGGYVYQKAYLEFFIAPDH
LERLIAQIEADPQITYHAVNARGDMRTNTTSEAPNAVTWGCFPHKEIVQPTIVESISFLA
WKDEAYEIGRNWARVYDAQSQTRKLLESVFGAVGEGGDTSSSNDEGTWFLVNVVHNDFKS
PDAIFKPFLAAAGEDANVPAVQRAQQAATSTASAVANGISEATSAVVEGVDGLVDGGNAA
VTENGAPAMAGR
>A0A0V0TNH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella murrelli|TrEMBL
MKIVQLSKIVIPDSVLTTLESIKENAEAVRNFGISYAVQLCRKLLNREHHVVPGLHFYTL
NQEKSTRSILEQIGFWKKAPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYLCRTRDWK
QFPHSRWGDVGNPAFGDLKHYLFSCIDQMDDSCALDMWDKELSTLEHVRDIFCNFIARTP
NRHGHSVRRLPWNENHLDPAADVLKNELIYYNSNGILTINCQAAVNGLPSSDPIFGWGEA
NGYIYQKGYLEFFASSTCTTILLNHVQNFPSINYHAINFDGSFETFNYDEDATVALTWGV
FVGQEIVQPTVANAASFRVWKDEAFDLWQRWAGLYESGSIGRKLLQRIHDDYRLITLIDN
DYPQPCSLSALLRAVISDYIGGKNLTTDDDRLACKKKFEISFS
>A0A1V3D0S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSAPTSLRVQAFLDAFSLEVSARAMPALGAEATRIPRGTTISIPWLASEDDDARLAAARR
VRELGFEPMPHLSARRIRSRTVLERFLQRAANKAGATQCLVIAGDLATPAGPFADSASII
ESGLLERAGIKVVAIGGHPDGHPVLGSDACWQVLEHKCQSIEARGMAPVIITQFAFDADI
VLAWLHALRARGIHVPVLVGVPGPASIARLVRYAAMCGVGASALMLSRYGISIGRLLGSA
GPEVFVDRLAGGLTDAHGLVSPHFFPFGGIAQSLDWINQHRALPSVARR
>Q3M8T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MRDCWGKNYISSFPSPQSPVPNTQYPIPPLVLSGVIRYTLKKNRHHHVMDDNHSYTALNY
FSKAAQAGEFLVTAEVAPPKGGNPTHMMEMAATLKGRVHAVNITDGSRAVLRMSSLVASA
ILLQQGIEPVCQMACRDRNRIALQADLMGAHALGIRNILALTGDPVKAGDHPEAKAVFDL
EAVRLLQLIRKMNQGVDCNDKPLTDGATDLFVGAAVDPQCASWSGLQSRFERKIEAGAQF
FQSQLITDFERLEKFMDKIASVHKKPVLAGIFLLKSAKNAQFINRCVPGVNIPEHIIERL
AKAKDPLEEGVKIAAEQVQIARQLCHGVHMMAVKREDLIPQILDLAGVSPVNRMLVK
>A0A417CHK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. AM42-2|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A2R3Q177|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSAPGSLRTEAFINTFSLEVSAKAMPALRAESGRIAPGTTISIPYLASEDDDARLAAVRT
VRELGFEPMPHLSARRIGSRAALERFLERAASEAGVETCLLIAGDLSAPAGPYADSTSII
ETGLLERYGIKVVAMGGHPEGHPVMNAGDRWRVLERKCQAIEARAMAPLIITQFGFDADI
VLTWLDALRARGITVPVLVGVPGPASIARLARYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVSGLTAGHGQISPHFFPFGGIAPSLDWIERYRRRTSAASA
>A0A7K1SQT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma arboris|TrEMBL
MFLEKIKSAESGVLLYGITPPKVGTPPERVAEIAQKTIERLTTLDIDALVVYDVQDEAAR
TKEERPFPFLNALDPLDFASNYLGSLNIPKIIYRPAGKFSPLELSDWLEELHKQNFYPVF
VGIPAPDFPVKTSLPEAYKIWSKHQDTSVIGAVTIPERHNLLNDEDVRILDKMSCGVSYF
ISQCIFNLDYAKQVIEDLVLNCKGKNISPPTIIFTITACGSTKTLHFMEWLGIHVPDELK
EDLKKSDDILEKSVKICLDIASELTTYCMERSIPFGFNIESVAIRKAEIEASISIAGGIG
QMLKNKGVRKASKDYEAQVVK
>A0A069DBV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. TCA20|TrEMBL
MADLREVLKNEVIIGDGAMGTQLYQMGVPVGVSYEELNLTSPEMVKDVHRRYIEAGARLI
ETNTFSANYVNLSKYGLEDQVEAINRAGVRVAREAMGNKGFVVGAVGAIRAGKRADISAA
KLNLYFEQQISALVGEGIDGVLLETFYDVEELVIAVRQVKKLTDLPIICQFAIDDVGRTF
DGFTMPEAFSILHKEGADVIGFNCRTGPNGIMRAMESVQNLGIPMSVFPNAGLAEYVDGE
YRYGASAEYFGQSAVRFADLNARIIGGCCGTTPEHIKAMVSALDTYEAAPLTVVDDELLP
VPDSVSETLADGSAAGTIRTDPTIVDLVKERHTVIVELDPPRDLDIQKFLTGAKSLKKAG
VDALTLADNSLAVTRMSNMALGYLAKEQTGLRPLIHIACRDRNMIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPDSSSVYDLTSFEIIRMIKQLNSGIAFSGKPLKQKADFIVGAAFN
PNVKYLEKAVQRLEKKIAAGADYIMTQPIYDPKLFVQLKEATSHLDIPIFVGIMPLASGR
NAEYLHNEVPGIQLSDAVRERMAGLEGEEGRKVGTAIAKELLDVAMEHFNGIYIMTPFMF
YGMSEELTHYVWEKSGRVIKT
>A0A2M8QCR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thermofonsia Clade 3 bacterium|TrEMBL
MSRSNFLERLAERPLLADGAMGTMLYARGFGFDECYDALNLKHPEVIVDIHRQYAAAGAD
ILETNTFGANAFRLAAWNLESSAAELNMRGVELARQAARDVRADILIAGAVGPLGVHLAP
LGNISREEAYRAFYEQIGALAEAGADLLILETFSDLAELEEALRAAKAACNLPVVAQMTF
NREQRTFMGVTPLQAVQVLTPWRPALIGANCSTGPQGVLEVVRHMAAAAKAVPGAPGLSA
MPNAGFPEVRGSRVFYPATPEYFAEYTKQFIEAGARLVGGCCGTTPAHVRAMRAAFDKLT
ASASTAVAIARVEIHHSAEGGHAHPHGDARIPTTLAQALAERRFVTTVEVEPPKSADTSA
IEETARMLKEAGATVLDISDIPMARMRMTGMAAAYRVQAGAEIETVLHFPVRGRNLLRVQ
GDLLAAHALGIRNIFVTMGDPTRIGDYPQANDHHDVVPTGLVQMIKAQFNVGLDGLGASI
GKPCAFFVGVAANLTPTDFEKEAKLLRKKIECGADFALTQPVFDAEMARRFIAYYEQMFG
KLTLPILAGILPLASVRHAQFLRNEVPGVMMPEAIVRRLEAAGNKTRTEGAIIAMEILAG
IRDLVQGAYFIPAFGRYDIVAKLIQQTTGQLQLSSS
>A0A292YWV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. N23|TrEMBL
MTSVTDPQDAHTPSPRHRLARALRRAGYEVLPFPSAHDKVLAHVPREVPLTITTTEAKGL
EPTLDLAVRLRAAGYRVSPHLAARLVRDKEHLVDIVDRLRDGGVDGVFVIGGDAAEPVGD
FPDALGLLEALGDIGHPFTTVGVGGYPEGHGAIPDAALAQALADKAPHATHVVTQLCFDA
AATTRWARSTALPVHVGVPGGYRADRLLSRLAPDFEGPVAGIHVFTFNDLDATETWRQNL
LARLT
>A0A292Z547|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. N23|TrEMBL
MSLREAFAAGRFAVTAEIGPPRGADPDAITRKAELLRGWVDAANVTDNQGAHVRMSSFAG
SLLAMRAGVEPVMQLTCRDRNRIALQSDLLSAGALGIPNVLLLSGDHPRFGDHPDAAPVF
DLDSTQLVWTARTLRDQGFLVSGREVGTRPGWLVGAVENPFAPPRSFRARRLAKKVAAGA
EFCQTQYVFDVEVFASWMARLRDLGVTERCKVLAGVGPIRSLRVMEFLRTGVPGIHVPDE
VERRLRGVPGDRVADEGVTMCVETIQRVAAIPGVAGVHVMAFGYERGVPEILERAGVGRR
PALSSSRSEGLGHAG
>A0A2D8ACP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleibacter sp|TrEMBL
MTTLSFEFFPTKSDEGTEKLLTVRDKLAAYNPEFFSVTYGAGGSTRDRTYSIVDEIQQRG
IAAAPHLSCVGDSKAEIRELLNRYKEIGISRIVALRGDLPSGAGLASSELRHANDLVEFI
REETGDHFTIEVAAYPEMHPQAPNLEKDLENFVRKAKSGANSAITQYFFNADCYFYFVDR
VQSMGVDIPIIPGIMPITNYSKLARFSDGCGADIPRWIRKQLEAYGDDSNSIMKFGEEVI
TDMCRRLLDGGAPGLHFYTLNQATPSLVVWKNLIS
>A0A1S2KHY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CC77|TrEMBL
MALGTPSTRTDRARTVRDLLASGTTYSFEFWAPKNEKGERNLWNALRRVEAVAPSFVSVT
YGAGGSTREGTVKATQDIAADTTLTPVAHLTAVGHSVAELRNMIGQFADAGIRNMLALRG
DPPGDPMGPWVPHPEGLHYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDTDVRHFVDK
CRAGADYAITQMFFDPEHYLRLRDRVAAAGCDTPVIPEVMPVTAVRQLDRLPQLSNAQFP
AAVKERILAVKDDAAAVRSVGLEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HPQS
>A0A327NZF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma telluris|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFSREETEDFLIDLHYLGID
NALVLRGDPAKPFTTFKAKENGYMYASELVEQVANMNRGIYLHEEDTTLAPSNFCIGVAA
YPEKHFEAIDHDIDFHYLKQKVDKGADYIVTQMFFDNQKYLAFVDRCRQEGITVPIIPGL
KPLSTRKQLQILPKLFHLELPEDLVKAVEACENDQQARQVGVEWCIQQCRELTAAGAPVL
HFYTMGKADNVMKIAREVF
>A0A386ZD40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia yunnanensis|TrEMBL
MSFDNVRGYSTPGRVSRTPQVSGTRSVVQQLGPRPDGSIPFSVEFNPPRDAAGEARLWRA
AREFERLHPAFVSMTYGAGGSTRDRTIRVTGQLARETTLLTVAHLTAVDHSVAELRSIVG
AYADSGIRNLLVLRGDPPGDVLGDWVKHPEGVEYAEDLVRMVRDLGDFHVGVASFPQGHP
RSDNLDDDTRYLVAKLRAGAEYSITQMFFDPEHYLRLRDRAIACDPVEGAKPIIPELMPI
TSLRTVERAVELCGRPLPARVMERLHRAAGDGPEENRAAVREVGIEIATEIAERLIAEGA
PCLHFITLNFAKATGEVLANLGYTMSPAPAHA
>A0A5P9GUI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. THAF29|TrEMBL
MTRPTPMALDQMQEAKKALEAPLFSDLPGDIDISFEFFPPKTEKMAETLWESVATLSPLA
PRFVSVTYGAGGSTRERTHEQVVRIQNEAKIPAAAHLTCVNATREEVDEVARHYWEEGIR
HIVALRGDPPDGAAHYTPHPGGYENAADLIAGLKKVADFEISVAAYPEVHPDSPDAQADI
ENLKAKFDAGADRAITQFFFDPECFFRFRDKAAAAGIEAEIVPGIMPVMSFAAVQRMSGL
CGTAIPGWMEGLFDGLDERPAARQLVSATIAAELCRKLYAGGVREFHFYTLNRAELSYAI
CHMLGKRPVGDAA
>A0A0V1PZM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Debaryomyces fabryi|TrEMBL
MPTVKERVQALKPHQRFVSFEFFPPKTDTGFRNLLARLNRMLALNPLFITVTWGAGGSTS
EKSLDLAATCQKEIGLTTVLHLTCTNTNKEIIDNALKKAKEQGVRNILALRGDPPRTEEY
WVPDCDFNNAVDLVRYIKEQYGDYFCIGVAGYPEGHVDGSDNSNQDPRNDMPYLVDKVEA
GADYIITQLFFDVDKFIKYEAMIRSYPQLKDIILIPGLMPITTYKVFTRATKLSHASIPL
EIQSSLHSSSYDDDLVKNIGIEVVNKIIDEIDSKTDDRIKGYHFYCLNLEKAVASIINNS
DVLKSVMDLPDETNDNEDAIASDSDEDIQPVAISNKRRKSSIVNDNELADKASAQKSLVS
KALIGDKRTLVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPTLKIYSPDEA
FHKWGAPESVSDIIKVFVSYLSGKIDSLPWVDAALSPETALIQEELFEVNNKGWFSLASQ
PAVNGCLSSDKIFGWGPSNGIIYQKAFIEIFIPKETWTNKLLPGLQKYLDDQSITYYCGD
SEGHLSSNLQIDKDQYNSKNAITWGVFPLKEVLQPTIIDLESFKAWNEEAFILWLEWARC
YKKTSKTYELLNSIYKDYYLVSLISHEFSDEYALWNILLENK
>L7IB80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnaporthe oryzae (strain Y34)|TrEMBL
MHIRDMLAETEKTGKPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVTQAQTYFGLETCMHLTCTDMGVEKVNDALSKAYKAGCTNILALRGDPPRDKEK
WEAAQDGFNYAKDLVSHIRKTYGDHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGRVRERGITVPIIPGIMPIATYASFLRRANHMQARIPEEWLQRL
EPIKTDDAAVRIVGRQLVVELCRKILAAGIHHLHFYTMNLAQSTALILEDLDWLPSPNKP
LKHALPWKQSLGLGRREEDVRPIFWRNRNKSYVMRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLLGTNEQNRKKFGEPKSVKDIATLFVRYVQKEVDTLPWSESPLDAEAEQIRDDLID
LNLRGLITINSQPAVNGVRSTHPIHGWGPPNGYVYQKAYLELLVHPAIFEQLKERIHDHP
DLTYYAVTKSGNLHTNATYEGPNAVTWGVFPGKEIVQPTVVENISFLAWKDEAFQLGMEW
ARCHDQNTPSRILIQSMMQEWYLVNIVNNDFHAPRTIFDTLKGLTVPDIDTEIVPPALPT
AVPEAAAINGERNGERNGAQANGATAAVTAS
>A0A023D2S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidomonas methanolica NBRC 104435|TrEMBL
MSGRLAVELVPRSREGLLADAALVRGILPEMSVINVPDLLRLPIRSWEAAALLEGRAGSV
IPHIRAVDVDPERPLHGADDPALREVLVIAGDPPPDPTHRTWPQSSAEIIARYRRELPHL
TVYAAFDPYRRSPREELEEIARKRDAGAAGFFTQPLFDRRMLDLCMNWLHDDTVFWGLSP
VIGPKSRAYWERVNRIVFPRDFDPSLDANIAFAAEVLTLAAERGDSAYLMPLRVDLAAYL
TPLKGIYRSPA
>A0A2L2Q1G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC00288|TrEMBL
MALGTASVRSDRARTVRDILASGGTSYSFEFYAPRTEKGEQSLWRAMRRVEAVGPSFVSV
TYGAGGTTRGGTVKATQKIASDSTLTPVAHLTAVGQSVAELRNILGQYADAGIRNMLALR
GDPPGDPLGEWIEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVVKAGCETPIIPEVMPVVNVKTLDRLPQLSNAAF
PARVKERILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A1X2DE88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sherrisii|TrEMBL
MTSTELGCPKRMEFGPCGGVRPDGQCEMRPGACVFADVVPWSGVVSAPRAVRAPLVLADF
SCTPFDRNDVAATAAVLAPGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWMTLSCRDR
NRVVLEQELRGLHSIGVETVLCVTGDGRGYDVCPDVTQTFDLDGPRLVSLAASVGMVAAV
PETPTAPPVHARPERLVQKQRAGASLAVLNHVPFPAIIAEFMTAATAAGLTIPVIAAVAV
FTDRVSAAVLQGLPGLELDESVTERVLGAADPVAAGVAAAVAEARALLSIEGVAGVNVSG
LASASGGRLGAEIKAEVGRVIRAEAS
>A0A4P9C984|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium maltosivorans|TrEMBL
MVNKMSSLLQQTLEAGKFAITAEMAPPKGTDFSHILEIADLLKGRVQGVNVTDFQSAAVK
ASSLAMCVELERKGLEPILQMTGRDRNRIAIQGEMLSAGHFGIKNMLALTGDHTTTGDNP
EAKPVFEMDSVSILQTAEVLMSGQDLAGNELQGSPDFYLGACVTPVFDPVEVQLIKMRNK
IRAGAKFFQTQGVFDIEVMREFKELTKDMDCYVLAGIIPLKSAGMAKFMNRSVPGISVPD
ALIERLTEAEDKAAEGIKIAGEFVAQLKEEGVCDGAHIMAIGAEENVPKILDIAGL
>A0A4P5UQP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobi bacterium|TrEMBL
MLTDTFKDILGTIPIIASGSIAMELSLRDKSDIPADIWNLKDPVTIESIYREFVDAGATL
LLTNTLKSNRLALDAFSLSDKVYEINRKAVWIARTAALRKALVAGVIGPTGHFFSPIGDL
TQEEAHQVFAEQAMALLDSGADIIMLSSFIDIEELIIAIDAVRAVNPEIPIIALKSFPED
GTVLATSYPADIASRLQEKTLLALGSNGIVGPQRMTDILRALSGATIPLCILPDIAIPTL
LHGRPNYNAEPEYVASVAVKLVRQGACIIGADGGATVEHIRAIAKAVSKEIPGSEKIAPK
PSKIIDVHPFESDEKSQFAQNIESRFLTTVEVEIPRGLDMSSVLEASRFLKDHGIDAVNV
FDGARARVRINPITASHMIMQETGMECITHMACRDRNMVGLQSDLIGAYSLGVKNILAVT
GDPTTIGDYPFATSVYDVDSIGLCRALNHMNQGRDLLGNALGRATQFTIACAVNPCADDM
ATELNRLHKKVEEGATIAFTQPVFDMDTLLPFLDAIKNLNISIMLGIIPLRSARHADFLH
YEVPGMIVPSWVREAMHNAGNSAGEIGLNIATEFLTQAKENVQGVYIMPPAKRYDMAIDM
CKRSGIL
>A0A1D3NGB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINRAAVKLAKESVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIAGMKRVIANITPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVIVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7C5MM63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MKIAKLLEKGRSISFEFFPPKTEEGYKDFFANIKQLKKVEPDFVSVTYGAGGSTKEKTQN
IVIKLAHEEDMNVMAHLTCISHTKEEIKTILENYKNNGIDNILALRGDPPNGCSYSVVNE
LPHASDLIEFIRLNYDHYFSIGGAVFPEKHPDSIDWDSEMKFLKLKVSKGMEFGITQLFF
DNKYFYEFLDRCEKTKIYIPIIPGIMPVTNYNQIQKFTQMCKATIPSILARQLEKFKDNP
SDIVKIGIEYGIHQCEDLLKNGVKGLHFYTLNKSFSSLLIYREIEKYF
>A0A7V1MKF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MERIRAEGVTLRVIPGILPITDLNNLEQFCDTCGTTIPSSISDIFEPLECLRGSTLLR
>R6ZR63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:534|TrEMBL
MKKEKTLQEVLAQRNVITDGAFGTYYAEKYHTREMPELANIEHPERVKEIYREYIEAGAG
LIRTNTFAANTVTMQKSFAQVERTIAEGIRLAKETVREAAGEKEPVFIAGDIGPIPVTGE
LSAEEIEKEYERILQCFIENGIRIFDFETFSDLEPLLPAIEKAKNKQELFVMASFCVNQF
GYSASGLSAKRLLHDSAKSGLIDAAGLNCGVGAGHMCKILEEMELPGKLFLMALPNAGYP
VLSRNQLTYGNAAEYFARKMKDMAALGVDFLGGCCGTDPGFIRSVKEQEHILEKGPKKLC
VRTGEEKPAVRRKGFLYDEKGAVKKKKLIAVELAPPFNANDEKLLESAHILMKSDVDVLT
FPDSPSGRTRVDSVLMAEKVRRETGMEVMPHICCRDKNALALRSLFMGEQINEIHNMLLI
TGDPIPAMERGAVKPVFHFDSVGLMKIAKEMNEEIFGDCPLSYGGAINQGRKNFEVELQR
VKKKLEEGAEFFLTQPVFTGEDADRLRKIKKQTGARILCGIMPLVSRKNAVFMKNEIAGV
NVTEEIVERYPEKATKEEGEMIGVGLAREVMAMVEDFADGYYFTFPFNRVHLLSKIMEET
T
>K2FQA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLAPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKSTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMSLSLARANFMVKHNVAGIVITPHMLRVLAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEHYIEQYRHYGLQELEALWNALWQVKT
KNELVPELAYYSRQPSSSQLIKYQQLHFMHRALFESKIAKGVGHFIFKASFWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A7H8PWJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbulbifer sp. YPW1|TrEMBL
MSKLRISFEFFPPKTEEGRDKLYNTREQLQGFNPEFFSVTYGAGGTTRDTTANIVTSLRK
DGISIAPHLSFGGDNEEIVLGLLERYKEAGVDRIVALRGDMPSGMGSVAQLVYANELVAF
IRRHTGDHFHLEVAAYPEIHPEAESYDDDIRFLKGKFEAGANSALTQYFYNPDAYFYFLD
QCEKAGIDAPIYPGIMPITNFTNLARFSRNCGAEIPRWLKYRMESFRDPEDVKKLGLEIV
TDLCETLLEGGAPGLHFYTMNQVGPTADILKALDLNIAQ
>I4HGF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa PCC 9808|TrEMBL
MTTRLQRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSKSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A4S0LC32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1C.F.Ca.ET.187.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDDMEARLWDTVTRLEPLKPQFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIREFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVA
GSAAA
>K1YZH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MNFKDIYSKPKLHISIEIFPPKDEAGVTSLFEALEDLSALQPAFISVTYGAMGSTRDLTH
DLALRIKNECKLPVASHFTCVGSGKTQIQDYIEKLKSAGIDLVVALRGDAPKGSAFVAPA
DGFQYANELVTYLKSLNGFSLAVAGYPEKHIEAASAEIDLDNLKRKVDAGADIILTQMFF
DNEYYFDFVERARARGITIPIVPGIMPIMNVKQVEKIAGMCGARIPATLHEQLLAKATDT
LAQREIGVEQAIKQCQELKKAGVPGIHFYSMNKSYSVMKVIAAL
>A0A4P7SA76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. PAMC28707|TrEMBL
MTSDAVRGRSSEGWVTRTPSIVDRLRTSTESKIPFSVEFSPPRDEAAEARLWRAVREFEQ
MQPAFVSMTYGAGGSTRDRTVRVTGDISENTTLLPVAHLTAVSHSIDELRSMVGAYADRG
ISNILVLRGDPPGDPLGDWTKHPEGVEYAEELVSLVRELGDFHVGVASFPEGHYRAVDLE
QDTRVLVNKLRAGAEYSITQMFFDVEDYLRLRDRVAAFDPEQACKPIIPEIMPITSLRTV
RRALSLSGSALPSEIDERFTRAAGTGAEEDRAAVREVGIELATSTCERLIAEGAPALHFI
TLNFARATREVLTNLGMCAARV
>R6ZXX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:534|TrEMBL
MTCLHYNKAEIDEFANILTDAGLKNILALRGDKNPNIAEKEDFRHASDLIAYMKAKWDFC
FLGACYPECHPESDDRISDVKHLKAKVNAGAEVLLSQLFFDTKLFFRFQEDCRIADINTP
IIPGIMPVINASQIRRMITMCGATFPVRFQKIIHKYEDNKEALFDAGMSYALSQIIDLLV
NDIDGIHLYTMNNPLVARRICEGIRNII
>A0A1I3B9A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomicrobium piriforme|TrEMBL
MRIKDIYARGFGLSFEIFPPKTEQGDESLFEHLDRLMVRKPAFVSCTYGAGGSTSKRTVD
LCRTIQTRWPASSTAHFTCVGSTRQDLIDWLDLAHREGIHNIMALRGDPPVGQTEFQQVA
GGLKNANELVSLIREHHPETGIGVAGYPEKHPEAPNADIDLVNLKRKVDAGADAVFTQLF
YVNDAYFQFRDRARKSGISIPIVPGIMPITEFARIKRITGMCGSVFPPALAAKLEKVQDD
KQAQFEIGVEYAISQCRELIDAGVPGIHFYVLNKSEATDRILEELKLPL
>A0A316Z3N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tilletiopsis washingtonensis|TrEMBL
AMSASSSASGVPEHITTLLAAAAHAERPLVSLEFFPPKTAQGMRNLHARIARMRAQLAPA
WIQVTWGAGGSTRESSLDIANAVQRDAHPTRGNACLHLTCTNVEKASLDDTLDQARSLGI
RNLLALRGDPPRGEEYWVASDARFQHAEDLVRYIRERHGDWFCVGLAGYPEGHCDATTPD
IERDIGFLRAKQDAGADFVVTQLFYCVDAFLDYLKRCRAAGITLPIIPGIMPIQNYQSFR
RMINLCSTRVPAEVTAALEPIRFDDAAVKEFGVRWATHMVGRIFLESDVRVFHFCTLNLE
NSVRCVVENLGWVDAEQQQAAAAANGVPDSPTMHRNLMLSERTASDFPKQLKVTTADTLR
QTLERSQLLRPPTLGAPPQQTTTWDEFPNGRYGDSRSPAFGELDGYGVSLKVPPADALRL
WGHPVTTADIAGLFTSYLSGSLSGIPWCDVPILDETAAIRSELLHLNRARGGADGGREWW
TVGSQPAMDGADSADPTFGFGPPGGYIFQKAFVEFFVETKDKDELRRRIDEEEGGKWMGF
FAGNRRGDFETNMQAGQVDAVTWGVFPGKEIAQSTIIEEESFKAWRDEAFGIWAEWELLF
PLRSPTRQLLRSIGDERWLVTLVHHDFKRPRALWDFLGCPPA
>A0A7X9UKM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. SZ31|TrEMBL
MKADLRKAMQERVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEV
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEIAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFAELGARIIGGCCGTTPDHITAMKEALANYVPSPILEPDPSE
TKARIVLHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLEKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>C3G866|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar andalousiensis BGSC 4AW1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7V8NS35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Acidoferrum panamensis|TrEMBL
MGIMRSGSHLEEVLRGGRFAVTAELNPPDSADPESVYQRARVIAPVCDAINATDASGAHV
HMSSVGVCALLTRAGFDPVMQVSCRDRNRIAIQGDLLGAAAMGVRNVLCLTGDGVQAGDQ
PQAKPVFDLDSMTLLRTASILRDKGEFLSGRKLEVPPRLFLGAAENPFAPPYDFRPHRLK
KKVDAGADFIQTQYCYDVPRLREFMAKVRELGVDQKVFILVGVGPLRTAKAAEWMRANVP
GVSIPDRIIDRM
>A0A8J6NDT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfobia pelagia|TrEMBL
MPSSRFQQSLKNPDDFTLTFELIPTRGGRNRKIDATLRLAGDLTIDGRIEAVSITDNAGG
HPALTPDVVGLEMKELGLDVISHFSCKDKNRNEMESLLFGWDRVGLHNLLIISGDYPQKG
YCGNPKPVFDMDSVHVLDLLSHMNTLEYSSHATMPTRFFKGVVVSPFKTTEAEQIMQYYK
LHRKIIAGADYVITQLGYDARKFHETLLYMQLNGLNKPVLGNVFIPSMPLVELMHKNQLP
GCVIPDSLYKEFQLEAKAKDRGKKARIDRGARLLAVMKGMGYNGAHIGGPGLTMEDFDFL
LTRATKYETEWESLIPDLTNWPQDQFYCYRKDERSGLNLPEQLPRKKPALIQKPRPTFTA
ANLTHVLVFESGGPFFKIAKKISLAMAETRLQRPFHLLEYLIKFILFKCQDCGDCTLSKL
GFICPQSSCAKYLLNGPCGGSRDGWCEIYPGRRKCLYVRAYQRLAPWKKEEQFKTGFVPP
RNWKLADSSSWINFFSGKDNSGGCSKE
>A0A3G5UFL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. FDAARGOS_527|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKETAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8F8PG14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. AB2/73|TrEMBL
MSSSSESHNAGIRISFEFFPPKSEEAEQQLWNTVEELSDWDVEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLATGVRRFVALRGDPPGGVGAAYQP
HPGGYANAAELVQALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRAAGIKIPVVPGIMPIQNLTQLKRFAGACGTNIPTWLDERFDGLDE
DVEERAKVAADVAAEQIQDLVRRGIHEFHLYTMNRSALVSAVLERLGLERKMDARAGAAA
>A0A351DLZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus sp|TrEMBL
MQINQLFKDRPVISFEVFPPRKNATAASLRKMDETLAVLSDLHPDYVSVTFGANGALQAT
GTLATASYIKDTYGIETVAHLPASQLSADQIHGLLNELQAHGIENILALRGDIPAGGRLS
NDFPHACDLIRYIHQCGDFNVIGACYPEGHPESPDLATDIHYLKDKVDAGASHLISQLFF
DNQVFYDFVAQARAAGITVPIQAGIMPVINAHQIERMATMSGVALPEKFTRMMARFQDNP
VAMREAGIAYAVDQIIDLLVHGVDGVHLYTMDNADVAQRIFAAAEQVIHA
>K9ENS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. PCC 7375|TrEMBL
MSTSNGFHSAPSLLRSAIANHKFIITAEVMPPKGGNPSHMIKMAQMLKGRVHGVNITDGS
RAVLRMSSLASAVLLKQADVEPICQMACRDRNRIALQADLMGAHALGIHNVLALTGDPVK
AGDHPKARSVFDLESVRLLRTIGQLNQGIDLNEKTLPDGPLNIFAGAAVDPQSPSWSGLQ
KRFERKVEAGAQFFQSQLISDFERLEKFMTQIAAQAQKPILAGIFLLKSAKNAAFLNRNV
PGVHIPDDIINRLATAKEPLQEGIAIAAEQIKLAQGLCQGVHIMAIRREDLIPEILDRAG
IGPIDKPTTSMETPQPLEFPVLQN
>T2IE84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocosphaera watsonii WH 8502|TrEMBL
MINHFRQAVQNKEFLITAEVAPPKGGNPTRMLEMAKQLKGRVHGVNITDGSRAVLRMSSM
AASALLLQYGIEPICQMTCRDRNAIALQADLMGAYALGLRNVLALTGDPIKAGDHKRSKP
VFEVESVRLLKMIDKLNEGIDFNDKTLADEPLDLFPGAAVDPQSRSWSGLQKRFERKVAA
GAQFFQSQLITDFEKLDKFMHQIAANSDKPILAGIFLFKSAKNAQFINNNVPGVEIPESI
IKRLGEAEEPLKEGIKIAAEQVKQAQQLCQGVHLMAVKREDLIPEILDQAGIPPMVSQ
>A0A257HR53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium PA1|TrEMBL
MSQPTISFEFFPPKSEAMEAKLWDAVSRLAPLSPDFVSVTYGAGGSTRERTHRTVKRILD
ETSLQPAAHLTCVAASKAEVDEVLREYWAAGVRHIVALRGDPPTGVGTAFEPHPDGYVNA
TEVTAAARRIADFDVSVSFYPEKHPESPSLQHDIDVLKAKIDSGATRAISQFFCEADVYL
RFRDAAAKAGITIPLLPGIMPVGNVAGYTRMATSTGTSIPAWFAEAFDGLDQSPEVRDMV
AASVAADLCLKLQAEGVDRFHFYTLNRAELSLATCRRLGLKTPVTEKDAA
>N9DZH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter beijerinckii CIP 110307|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKTVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDADIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A178HGK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aerococcus urinae|TrEMBL
MKTKELFKGKTLFTYEVFPPNAKSSSASIYKTLDGLKELAPDAISVTCGALGSDNRLKSI
EIASLIKNYGIESVIHLPCLYETQASIDEKLAELKAANIENILVLRGDPKPGQSPKEDFP
YAADLIRYIKSKEDFNLIAACYPEGHVDAPDPITDIRYLKEKVDAGSDQLISQLFLDNDY
FYRFLERADLAGIDVPIEAGIMPVTNKKQIESMARICGVQIPDKFRRAMEKYQDNPLALR
DAGLAYAIDQIVDLISHGVDGIHLYTMNNPYVARYIYQAVKNLL
>A0A378YPV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea pnomenusa|TrEMBL
MTQPSFSFEFFPPKTADGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQGTLDTVVEIQR
EGVEAAPHLSCVGSTRENIREILQTYRQHGIRHIVALRGDLPSGMGEIGEFRYASELVEF
IRAETGDWFHVEVAAYPEYHPQARSPRLDLEHFANKVKAGANAAITQYFFNADAYFRFVD
DVARLGVQVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDREAIRAFGLDV
VTGLCERLLAGGAPGLHFYTLNAASATKAMWQRLGL
>A0A0W0HDV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNVEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISTMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1I3ST83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrisporobacter glycolicus|TrEMBL
MSKLQEAFERGEFAVTAEMAPPKGTDLSHLLECAKLCVGRVHAANVTDFQSAVMRATSLA
TCKLLKDIGLEPVIQMTGRDRNRIAIEGEMLSAGVLGIDNLLALTGDHTSVGDHPQAKPV
FDLDSVGILKTASTLNAGTDSVGLELQGKTDFYLGACVTPEYDPIEVQLLKMQKKINAGA
KFFQTQAVYDIEHMRKFRELTKDMDCKIMAGIVPLKSPGMAKFMTANVPGIFVPDDQIER
LKAAGKGNYVQEGIKMAGEFIRQLKEENLCDGVHIMAIGAEENVPKILDEAGL
>V4J2Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp. PB-SRB1|TrEMBL
MKSGSNLERVMAAGHFAVTAECGPPRGADPDHVIKKAELVKGNVDACNVTDNQTSVVRMS
SIAGCMLVKQSGIEPLLQMVVRDRNRIALQSDLLGASALGVRNLLCLSGDHQKFGDDPQA
KNVFDIDSIQLIHLVKTMRDEGVFPSGDKLDGAPKFLIGCAVNPFADPYEIRVPRFKLKV
DAGADFVQTQCIYNMDVFKKYMEDVKRQGLHERCKILAGVTPLKSAGMGKFMNRMVAGID
IPDSFIKRIADEPKEKQAAKGIEMCIEQIHELKEMEGIAGVHVMAIEWEEKLNEIIGGAG
LLPRPVVEHETVH
>A0A719REB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Typhi str. 404ty|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVVDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6P3BQU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia contaminans|TrEMBL
MKTIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNTAAATRTICERLVM
>A0A5N9H5W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MVKVTASFNKLTRKPCFICDYSPPKSGLTESNALYPDMADYILVNSSPGFSVRASSSMVA
AYIKGNAIADPIFTVVTRDMNKLALDSLILGGSIIGLENVVVVGGDRFHSERSDNPTAIN
DYTTTELIRSIVNLKQGIDYRGVELDRPADICVGSVLDLSSGVNKEVMLARKKILAGVEY
FITQPVYDMGSVDMFYDLYRERFFEDIKVPILWGIQIPDVNSISLTMFPDWVEDALNDGE
DPVAIALRLYKPFDCRDLKDMYIVPTIYKGGHRNYSSANIFMSTAKQT
>A0A521CIB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium resistens|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAVDLVRQIKDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A0U3FMT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium limosum|TrEMBL
MVNKMSSLLQQTLEAGKFAITAEMAPPKGTDFSHILEIADLLKGRVQGVNVTDFQSAAVK
ASSLAMCVELERKGLEPILQMTGRDRNRIAIQGEMLSAGHFGIKNMLALTGDHTTTGDNP
EAKPVFEMDSVSILQTAEVLMSGQDLAGNELQGSPDFYLGACVTPVFDPVEVQLIKMRNK
IRAGAKFFQTQGVFDIEVMREFKELTKDMDCYVLAGIIPLKSAGMAKFMNRSVPGISVPD
ALIERLTEAEDKAAEGIKIAGEFVAQLKEEGVCDGAHIMAIGAEENVPKILDIAGL
>A0A4S3JPV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus tanneri|TrEMBL
MHVKDKITQNDSAGRIGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDSALQAAYKAGCTNILALRGDPPREKET
WEATQGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDNFIEWIKKCQAKGINVPIIPGIMPIQTYGAFLRRANWTKARIPPDWLETL
EPVKNDDAAVKDIGKGLVADMCRRLLASGIKHLHFYTMNLAQATQLVLDELNLLPSEETP
LQRPLPWRPSLGLNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNVQLWGEPKSIRDLTHIFVRYLEGKLDRLPWSDTPLSSEANVIKDNLIE
LNNRGFLTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLVPSYLLDELVSRIEKNQ
DLTYHAVARTGELRTNTRDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHDAASPSRKLIQGVVDSWYLVNIVNNDFHNTFSLFELFKDLNVKDLDSEVSADNVDEK
HPANGAVPEAMVKN
>A0A2V9X3U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPSDLLAHLKTSAVLCDGAMGTLLYSKGIFLNRCYDELNLSQPDLIRNIHHEYLQAGAEI
VETNTFGGNSFRLARHSLADRARDINLAGARLAREAAKSFDLWVAGSVGPLGILIEPLGK
TSYQEARDSFREQIEALVEGGVDLLILETFGYLEELHQAILAARDVNPKIPVVAQVTIDE
DGNCLDGADPETFAAKLEEWGADLIGCNCSVGPVAMLDAIERVHAATSLPLAAQPNAGVP
RSVEGRNIYLCSPEYMASYARKFVAAGVRIVGGCCGTTPEHIRVMKAALRVGGARAKASG
SHGVSTPPAPSAGPTIPLEERSRIGAKLARGEFVTMVEIVPPKGTDIRKEVEGARFLKSV
GVDGINIPDSPRASARMSNQALSLLVQQEVGIEAILHYTCRDRNVLCIQSDLLGAAATGI
RNLICITGDPPKMGNYPDATAVFDVDAIGLVNIVHNLNRGLDIGGNPIGQGTGFVIGVGA
NPGIPNIDEEIRRFEFKVGAGGEYAVTQPVFDLALLENFLRRIEHCRIPVVAGIWPLVSV
RNAEFMKNELRVSVPDSILERMGRAATPDAARAEGVAIAREMLTALRDMVQGAQISAPMG
RYSSAVDVLEALGSAASARPAASR
>F0U6Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces capsulatus (strain H88)|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNILALRGDPPREKEK
WEAIEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDDQDDPDLLMQHLKEKVDAGGTF
IITQMFYDVDNFLAWVNKCRENGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEAL
EPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQATKMVLGELELIPSHKTP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSLKELSEIFVRFLNGNLDRLPWSEGAVTEETDVLKLDLLD
LNRRGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNP
DLTYYCVNKIGELRTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHVASSPSRRIIQQVMDSWYLVNIVNNDFHKTHDIFNIFKDLKVENLNVQVEPIAPAAE
LVDNTRENSQDPQKQVNGSSTELTESKQEIPSN
>A0A7H4H892|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hominis|TrEMBL
MMSHEPRATAPIVDDVSPRSARTVPFSFEIYPPRTAEGLPALHETIRVLAATGPRFISVT
FGAGGSTTDRSLAVLTHILRETPVPPVAHLTCVGSSYAEATTVIREFLDAGITRFLALRG
DPPAGVAEDEVALGDLESAAQLVQLIDRVQAERSPYREQEIPGVPGAAQVAAGERVEIAV
AAFPNGHPRSRHRFEDIDALLAKQAAGATSAITQLFFRSADYLDFVSRARAAGVVIPILP
GIMPITSPARLRRVLELTGDPRPDDLAVALEAATDAAAQRAVGIAHAADLARAVLDGGAP
GIHLYAFNNHDTVLAVLRAAGLIPEETTP
>A0A063CQT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1A5X166|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia tropica|TrEMBL
MKPIELSFEFFPPKTPDGVEKLRATREQLLAFKPRFVSVTFGAGGSTQQGTLDTVADIAK
QGVDAAPHLSCIGATRDSLRDILAQYRSHGIRHIVALRGDLPSGMGEMGELRYASDLVAF
IRAETGDAFHIEVAAYPEYHPQARSPRHDLEAFAQKVKAGADSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDREAIRAFGLDV
VTDLCRRLVDGGAPGLHFYTLNAANASKAICERLGV
>A0A5J5PSP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium barbadense|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFDRMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFIKFVNDCRQMGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQFPHGRWGDSRNPS
YGALTDHQFMRRRARDKKLQEEWATPLKSIDDIQEKFKSFCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSLSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGTTDVNAVTWGVFPAKEIIQPTVVDPASFMVWKD
EAFEIWSRAWAALYPEGDLSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>S3T5S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter colistiniresistens|TrEMBL
MLSLFAQHLGQDRFCILVEYLCSIPSILPVPQSIAGFPAMMTLADRVQTDEDPEPIEFAQ
HYPETIEKVLHFSGKGRDITEFETFLDQAEQAGQKNLLLLTGDKLKKHSSGQRLATDRTR
YLESVNAVIAAKKRKTFHIGVAFNPFKYTEAERDAQYFKLHKKIRAGADFLITQLGFDLE
QTKHAQAILALDYPDFPLIACVMPLTLRRAQFMQRHQVAGIVISEHILKVLEQEDRGDSA
QAEKNVYARCALQILICKHLGYKGVHLSSCHKPQEQAQLEQALQQYQHLSLTECEQLWYQ
LWQTTTHRVFQPRVDIFRKKVTSTQIFKYKNMQLLHGVFFSSKAALQVGRFVFKAAFWDR
PNASHLLLKVEHFSKHHVVGCDSCGQCRLSETLYICPETCPKGLANGPCGGTTLDRCEFG
DRECIHSVKARLAKVVGQTELLKTELIPAVSIETRATSSWKNWFKSIEP
>A0A1B1NKK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio scophthalmi|TrEMBL
MGYTHASHIDALNQNVAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKNLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDASRQELVQIADDYWANGIESIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFNQASRFAAQNHVKVPGWMAKQFE
GLDDDPTTRQLVGASQALDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A5W1EGC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. arizonae serovar 18:z4,z23:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8C8FL19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
AFHDGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTESGDHWFSLEFFPPRTASG
AVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCN
QTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKHIRCEFDDYFDI
CVAGYPTGHPEADSYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVRDCRAIGITCPI
LPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIRNYGIEQTVGMCRVLLES
GNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPK
SYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEELTSEQSVY
EVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMMDELDKVNRRGVLTINSQPTINGKP
SDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPRVNYHIVNVHGQNTTNAH
DMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAELYDDESPSRMIIKYI
HDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPTEQPVEQPAEESPVEDQSPK
>A0A8G6ZFN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAKLPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A8H6UF62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus hiratsukae|TrEMBL
MHVKDKLAENEAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALSAAYKAGCTNILALRGDPPRDKEA
WEATDGGLRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSTF
VITQMFYDTDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFMRRATWTKARIPPDWLEAL
EPVKNDDAAVREIGKRLVADMCRRLLAAGIKHLHFYTMNLAQATQAVLDELKLIPSEPLQ
RPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDAYG
IGLKGTNEQNIKLWGEPKSVRDVTQIFVRYLEGKLERLPWSDSPISSEANVIKDSLVQLN
SRGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDDLIARIEKNEDL
TYHAVGKKGELRTNTHDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRLGEDWAKC
HDAGSPSRKLIQDIMDNWYLVNIVNNDFHNTYDLFGLFNGLEVKDLDVEVVPETVETKPQ
TNGAAPEEVAVKN
>A0A7Y2N265|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp|TrEMBL
MAATVTGSKLEKILKSGHQAVTSECGPPRSSDPAHIKEKGELIKDHVDSINVTDNQTSVT
RLCSLAACIHLKGMGLDPVLQMVVRDRNRIALQSDILGAASFGINNILCLSGDHQSFGDS
PQASNVFDLDSMQLVQTVRYMRDEGKFLSGDEIKAPPDMFVGAAANPFGDPFKIRVPRLA
KKVASGAEFIQTQCIYNLDKFEKWMEGVRARGLHEEVYILAGITPLRSVGMARYLQKNVP
GMDVPDELIERMKGVDKKKQSDEGINIAIESIQRLKEVEGVAGFHVMAIEWEEKVPEIVE
RSGLYPRPQID
>A0A8C8FXX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
MVNNVQRVDDTWRTCTKSNSSGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEADSYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIR
NYGIEQTVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMMDELDKVN
RRGVLTINSQPTINGKPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQW
AELYDDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPTEQP
VEQPAEESPVEDQSPK
>A0A174SIL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster clostridioformis|TrEMBL
MKTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTREDVLLILEQLKEQKIENILALRGDRVPDREPAGDF
RYASDLVEFIKLHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFRERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFISVMERYGDNPIAM
RDAGIAYAVDQIVDLAAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>A0A6J0AGH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vicugna pacos|TrEMBL
MVNEPRGNGGPNPRSEGSSSGSESSKESSRCSTPGLDPERHEKLKEKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETVLHMTCCHQSREEITGHLHKAKRLGLKNILALRGDPIGDQWEEEEGGFNYAADLVKH
IRGEFGDYFDVCVAGYPKGHPDAESFEADLTHLKEKVAAGADFIITQLFFEADTFFRFFK
ACSEMGIACPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCRELLESGLVPGLHFYTLNREVATTEVLKRLGMWIEDPRRPLPWAISAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GKELTSEESVFEVFVRYLSGEPNQDGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETTEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWTEQWGKLYEE
ESPSRMIIQHIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRAPQNERETEAP
>A0A1C3SU21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus piscium|TrEMBL
MKITDIYKTKNKKNKSVISLEIFPPKTDAGVETIYHTVAGLTNKPDFISVTYGAMGSFNQ
GNKTLRIAEKIKKDYNIETMHHLTSINNNPEQIAAILSDIKAKNVNNILALSGDMPVGAA
CSDFPDAYHFAYELINDIKKNGDFDIAAAIYPEGHVNSALEVENIEHVKRKYDAGANLFV
SQLFFDNEKFLRLNDYIKNSGIEAPIAAGIMPVLQKSQVERMIFFGASLPTRLIKIINKY
KDSPEDLQKAGMEYACKQIDDLLARGVDGVHIYTMNKPFVANTMMTKYL
>A0A2U3XVU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptonychotes weddellii|TrEMBL
MVNEPRGDGGPPPRSEGSSSGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSQEQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRH
IRREFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDDAIRNYGIEQ
AVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFACYLSGEPNQHGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPTPEQGAEAL
>A0A818Q171|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood1|TrEMBL
MTLTHTEKSTASNHCDVHQNGIDNRKMSNSSDYFGEFKHSQSEHTLLNTRANSLPPVKYI
SLTEKIQKRIANNDRWYSLEFFPPRTTNGAVNLIGCLERMAVSEPLFCDITWHTAGDPAG
TKETSTMMIANTMLNYCNIDTMLHITCYGAKKATMIEYLSKAKDFGIRNLLALRGDPPVG
EKWNPEKTDFRYASDLVKFIRENFGDYFVICVAGYPKGHPDSKTYEEDLHYLKEKINCGA
DFIITQLFFQAETFLKFQSDCQAVGITCPIIPGIFPIQAYASFKNIVRLTKLDVPDEITA
HMESIKDNDEAIRDFGVQTCVDLCKGLLDSGKVHGLHFYTLNREYATSEILKQLGFGFED
PPLRALPWKKTSKNHVRSKEDVRPIFWSTRPKSYIHRTSDWNEFPNGRWGISSAPSFGLL
TDYHLFYMKIDATRDELLDEWGHELTCEQDVWKMFVCYIGGKKNSSDKILRHFPWKDEEI
SPETNLIHNELVEYNRKGILTINSQPVVNGKPSTDPIFGWGERNGYVYQKAYLEFFTSAN
NIPALRAVLKNFPGVNYHFVNKSGEVNETNADDEQPIALTWGVFPGREIIQPTVVDPVSF
MIWKDEAFGLWMERWGKLYEPDSRSYSIIEQISNTYFLVNLVDNDYPQGSCLWAVLDAMF
EYQQKTNQDINR
>A0A1S1NU95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kushneria phosphatilytica|TrEMBL
MTSTAFHTSFEFFPPRTEAGRDKLMGVRDRLVEQDPSFFSVTFGAGGSTREPTFDTVCQV
RETGINTAPHLSCVASDKASLRDLLHRYQEAGISRIVALRGDMPSGTLAGGELRYARDLV
DFIRHETGDHFRLSVAAYPECHPQASSFEQDIDHFVDKVRAGADMAITQYFFNAEAYFHF
VEQVRRRGVDVPIVPGIMPITNFTKLARFSDMCGADIPRWIRRQLEAYGDDSESIRAFGE
EVVSTLCQRLVEGGAPGLHFYTLNQADASLAILGNLGLGQRQVSAC
>A0A533VYB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MVECLKLRQKLERRDFLRIVEVFPPNFTAERDREPLIGLRQKTRDFLERVKKIQNLADAI
LVADVKDLSRLKLGTIYSAAMVQEEVGIEAVPVITARDSNRPAIRSAILTALSLGLDSLM
FVWGDTYADDGAKNVYDYTGVGEMMIEAGALFERAGVRPTFFAPIDLATLDAPRGRRLAH
SRLKSGAEYLLAQPPTADVSYTFPSHMRTLRRRRLNSRVLLNVFPFRSSDDIEYCRKKFG
WDIPPHLGAIAEKGGEPELLREAKRVADRLRAVGCQGVYVSTRGRPELARFILD
>H1XYT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldithrix abyssi DSM 13497|TrEMBL
MKVIEHLARAKETLLSFEIIPPKRGGDIHSLLRVVDDISKYNPPFIDITSHAAEVKYEET
PQGIKRKVKRKRPGTLGICALIQNKYNIDAVPHVLCNGFTREETEDFLIDLQYLEIENVL
ALRGEENSYQKPLVNGRSANRYAVDLVAQINNMNKGIYLEEELIDARPSNFCIGVAAYPE
KHVSAPNLEFDIKQLKKKIEAGAEYVVTQMFYDNRYYFDFLDKCRAAGIDVPIIPGLKIL
TAKSQLTSIPANFHITLPSELTDPVLEAESDEDVLEIGVDWAYKQVSELIEKKAPAIHFY
IMQNSKPIRMLMKKLGF
>L1JWQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Guillardia theta (strain CCMP2712)|TrEMBL
KFYSLEFFPPNTLEGARSLIARVDRLAKLQPLFVDVTWNMESGKRAIETLVAAKAVCSLD
VQMHMSCTGITKKMADDLLVEAMDADIRSILVLRGDPAPGKSDWEPVADGFKNASELVSY
IRHKYGDFFSLSVAGHPGKHPASSSKEEDLEHLKQKVGCGADFIITQMTFKASEYQEFVG
SCRRVGIDCPIIPGVLMIPPSLEKLRAVCNHCSVEVPEDLVELLEVSKSDGAELSHCSSC
CCPPLARVSSRAISGAPGLYMYTLNLEKSAQEIVRAAGRQRDSRTDPMLPGHKPQPQGPR
RRHVRPIFWASNAISYLTRTRNWSADFPSHHSIVGRRLGSMAERRNMCAGLTSLSRSQLT
RRRWGESPSTEEDVFDVFERFVRGFVPRLPWCDRLEKETLASGILKPLATLNHYGYLTIN
SQPRVNGAPSEDEQFGWGPRGGHVYQKAYLEFFCSPGNLDRLLEALGSHPSISLEAFNMR
VDRLNDDRHISAVTWGVFDGSEVTVPSPLPTLHLIFSFYSEEAMDMWKSVWASIYPERSE
SRSLIKKIHASYWHVYMVDNDFVKGDIFKVFSEV
>A0A0M4LJ73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. infantis|TrEMBL
MHSPMFTLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEQAGVSAVLALRGDYIDGERLVGDFNHASDLV
SYIRSMKPDLTVFGACYPEGHYQSGSLDQDIENLKIKVDAGVTRLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLDALLNRWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A076Z9E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus agalactiae|TrEMBL
MSKFLEKLKTDILVADGAMGTLLYTYGLDTCHESYNVTHPEKVLAIHQAYIEAGADVIQT
NTYGAQRHRLKNYGLEDQVVSINQAAVNLAHQATLGKETFILGTVGGFRSQRQCDLTLDN
IVEETLEQVEALLATGQLDGLLFETYYDIEEITTVLKIVREMTDLPIITNISLHEAGVTS
NGKPIVEALSQLVMLGADVIGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASQLSLDGE
NSQYQFSQNSEYFGKSAELLVAEGVRLIGGCCGTTPDHIRAVKRSIRGLKPIERKVVTPI
IPVKDFVRRIRRTDTLVDKVKKEVTIIAELDPPKHLDIVQFQKAIRAIDQKGIAAITLAD
NSLSNTRICNLSIASLLKDEISTPFLLHIACRDHNLIGLQSRLLGMELLGFNHILAITGD
PTKLGDFPGATSVYDVTSFKLLSLIKQLNQGLSYSGASLRRPTDFTVAAAFNPNVKNLTR
TVKLIEKKVASGADYFMTQPIFDHSVLKELADLTKTVEQPFFIGIMPITSYNNAVFLHNE
VPGIKLSESFLSALEKVKDDKEACLTLALNESKSLIDEALNYFNGIYLITPFLRYDLTLE
LIDYIQKKQVRKSS
>A0A537EUY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MRMSDRARHHNLVTVELIPDRVVPSDLALLRGRVDAITVPALRNGHNDPSYPKSFQVTPQ
RRSLASAAIINRAGITAVPSLTCRDCRRSDLSTISSQVEEGLGNVLIVYGDPYPEHRSGT
YEFTKTNELIREVSSLNGGSDPCIGAVTNQHVKDKESEISRTISRVDAGADFIVTNVAFD
SESVLDHRDSLLEAGLNVPLFIQVSIPLSLDNVLFVSQKFDIPVPAHVRKRLLDDPVGGS
LAVAAEAYEALHGEANGIHFSYLFRQRNPIPTYRHLLETIGIAGPTLAPLTTSAVKTYPV
A
>A0A429T731|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC05374|TrEMBL
MTTLRDILAAGTPSFSFEFFPPRTDAGTRTLWQAIRRIEPLAPTFVSVTYGAGGSSRDRT
IEVTQRIAAETTLRPVAHLTAVGHSTAELRRIIGQYADAGVRDVLVLRGDPPGDPNAPWT
PHPDGFTHAHELVSLVRELGDFSVGVAAFPERHPRSPDWESDIRHFVAKCRAGADYAITQ
MFFDAEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQISRFAELSHATFPAPLARRLDAAR
DDAAAGHRIGVEYATAMADRLLAEGAPGLHYITLNRSTATLEIHQNIQNSRSAHVLAAAR
>A0A1H6CS19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobellus limi|TrEMBL
MSVGTQRGVADGVTQLLSTARFELMPFDSFEGELSELPEGATVAITTSPQLGIDRTVEKC
EEAAEAGYEVVPHIAARYIEGPEELEEIARRLTEAGITDIFVPGGDKEEAVGEFESAYDL
LVALEDLEYEFEEVGITGYPEGHDFISEEELAEAMEKKAPYATYIVTQLCYDPDTILEWI
EEIRGRGIDLPVEVGIPGVMKYEKLINISRKVGVGDSVKFLRKTTGIVGFIKQFIGSRGR
YKPDELIEGLAPYVDDETYKLQGLHIYTFNQTSDLESWRQSRLNG
>A0A1R0XE35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus odorifer|TrEMBL
MTPPKASHAPEKVSEIAQKQVERLKNLDLDALILYDVQEEVDRVDHERPYPYLPTIDPAV
YGDKYLRQVEVPKIIYRCVGNDTRAQFEDWVKTDENEDRFSVYVGASSSKQEVKLNLPDA
YELSKQLNSNLTFGGVVIPERHIKKNDEHIRVVEKTNNGCNFFITQATYNVEASKNLLSD
LYYYYTNNGFEMVPILFNLAPCGTAKTLQFMKWLGISIPGWLENELKYSNDILDKSIQLS
QKIFEELLDFGLEKGIPIGCSIESVSTSKLEIEASVQLVKDVKAILDKKLPTK
>A0A3D4U326|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MARLLNRLTQGQFVVTVEIDPPRGPDAAKTLEKVRGFADRVDAVNVADCPMANVRMSPIT
LAHLIQRDAGVEAIFHLTCRDRNTIGLQAELLGAAGLGVRNILALRGDEPTRGDHPSATG
VFEIGSSRLIKLASTLNAGSTIGGSGLDCGTDFTIGCVANPNAEDLEAEVDRLEAKIAAG
AHFAQTQPVFDLRILEHWLMKVAGRVRIPILYGVMPLRNYEFAVHLNNDVPGITVPEWAV
ERMRVSGPQAGMEMVREFISSAFAASEISGIHIFPMNNAARILKVVDIIDELGVRCQRKA
KPIRIETRD
>A0A0T7RWH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Bovismorbificans|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A174KL99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELAGEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A0M6WVU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia faecis|TrEMBL
MKVSEILKKNEVTISCEIFPPKQGAQLQNYKAIAAEIAKLKPAYISCTYGATGGTSDYTV
EIADAINSYGVPAIAHLTCVSSTREKVHTVIHELKERGIENILALRGDIPTNTDFPLPDQ
YHHAIELIREIKEAGDFCIGGACYPEGHPEAANMNEDLDHLKEKVDAGCEYLTTQMFFDN
NIYYRFLYKALAKGIDVPVTAGIMPVTNAAQVKRTISLTGNLVPAKFLSIVDRFGDNPAA
MKQAGIAYATEQIIDLIANGVNHIHIYSMNKPDVAAAIMNNLSQIYVREQA
>A0A2S7DW48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas cucurbitae|TrEMBL
MTHLSFEFYPPKTDEQRAQLDRTAAKLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIGELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAIDALSDLRYFKAKVDAGADAAITQYFFNADAYFHFRDA
VQRLGVDIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDADAVRAFGADVV
ASLCERLIAGGVPALHFYTLNLAKPTTQVLQLLGR
>A0A369Z3F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parainfluenzae|TrEMBL
MSYANEINTLNQHLADTNKKINVSFEFFPPKNEKMESMLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGIEAAPHLTGIDATPEELKEIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIEAEIVPGILPVTNFKQLQKMASFTNVKIPAWLAKAYEGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHTLGIRPTANP
>A0A323VBD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter versicolor|TrEMBL
MTGTVRELLQSERPTWSFEFFPPKDEVGEAQLWTALRELERLRPSFVSVTYGAGGSTREG
TVAVTERIAAETTMLPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WVAHPDGLRYAAELVELIKGIGDFSVGVAAFPEMHPRSPDFEADTDMFVAKCRAGADFAI
TQMFFRVEDYLRLRDRVAARGCDVPVIAGVMPVTSARQISRIVQLSGQAFPTELADRFAE
LDGDTPDHKRAVRAHGVEVATDMCRRLLDEGVPGIHFITMNRSTATTEVYESLAGVSAL
>A0A1P8TMB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces alfalfae|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGDWVAHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSTDWESDTRHFID
KCRAGADYAITQMFFDPEEYLRLRDRVEAAGCDTPVIPEMMPVTNVRQLDRLPQLSNAVF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHRRA
>A0A1D8S6D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halodesulfurarchaeum formicicum|TrEMBL
MTQDPVRDLLADPHFELLPFAGLFDQAAKLPEGSTVALTASPDKGVDETVELSTELADRG
FEVSAHIAARAVRSDEHLETIAETLLDAGVEDIFVPGGDNETPEGPYDSAYALLSDLEEM
EYEFERVGITGYPEGHQFIDDDTLREHLLKKEEYADYIVTQMTFDPDAVADWALEIREDD
VELPIIVGVPGVMKYQRLLSISREIGVGDSLSYLRKTTGVFDFIKQFLGSRGQYAPDDFI
QGIGEYYADDSYGIEGVHLYTFNQVGDAEDWRQQYV
>A0A498C915|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas rhizophila|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAAKLKVFAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASELISFI
RAEHGDAFRIEVGAYPETHPQANDALLDLKHFKTKIDAGADAAITQYFFNADAYFHFVDA
VRKLGVTVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAEAVRAFGAEVV
ASLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLRG
>A0A0B7LPW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A5I4FBQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Uganda|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2D8Z399|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHITDIINKGRPTFSFEFFPPKSERASESLFETIKDLESLAPSYVSITYGAGGTTRERTH
DLVEKILEKTTLIPIPHLTCVQHTEEEISNILKRYSDKGISNILALRGDNPKGDAQYDRS
KDSFCFARDLVEFIRNFDNSTLDKKSKSFGIGVAGFPEGHPETPNRIKEMDHLKAKVDSG
ADYICTQLFFDNHDFFDFRDRCELAGINIPIIAGIMPVTSISGMQRMADLAAGSRFPAKL
LKSIDRCNLDSSAVERVGIQYATEQCSDLLNNGVDGIHFYTLNKSKSTRGVFEALGINKT
>A0A2N5XWT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohaesibacter celericrescens|TrEMBL
MNHNAERSGRRSQTAEKLNISFEFFPPKTPKMEENLWACVKRLAPLCPDFVSVTYGAGGS
TRERTHATVERIITETHVPAAAHLTCVGATKAEVNEVVESYAACGVKHIVALRGDPADGV
GSKYVPHADGYVNAADLVAGIRDIGGFEVSVSAYPEKHPESPDFATDIEMLRQKVDAGAT
RAITQFFFDNDLYEAYVERARRAGIFIPIVPGILPIHNFVQMANFAGRTGASVPQWLANR
FEGLDNDPETHRLVAAAIAAEQVNDLHERGVDDFHFYTMNRANLSYAICHLLGMRPVAV
>A0A5H6RLM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Reading|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6I2VMQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSTLEHKLTSTNEMVFTAEFHSLDGNGLEKAKKYADRMLGWFDGVNSTDNTAAHAHASNV
ATAIAIKQLGLEPIMQVVCRDKNRLAQQADIMGASMFGVENFVALTGDDVTAGDEPEARR
VFDLDGPQLVRLMNTIKRGEYMSGRKIDPAPHMFIGAVENPGAPPFEYRVERVAKKYEAG
AKFLQLQICYHQDRLERFCAGVKDAGLAGKIAIIPSVVLVKGPRPLNFMHNSVPGIDVPA
DQIARVESASDPAEAAYLQTLEFAQHALAQPGVRGLHITDFRNDETLERLMTDLGRVRQT
STNEVKDDHAYSA
>A0A2G9E9X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium pseudoperiodonticum|TrEMBL
MKIADIYKGKSLTTSFEVFPPNDKVGLDQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIADRIKNQNGVESVAHLTCIGAKKEEIDKVLEDLEKHNIENILALRGDYPVDRELEVGD
FSYARDLINYIHEKKDDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A3G2HMH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas monteilii|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A6I3AYU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSAPTISFEFFPPKDVAGEERLWGAIEALGPIAPDYVSVTYGAGGSTRDRTISITSEITK
RTQIPTIAHLTCVGSTQEEILHILTRYRDAGIKSILALRGDPEGGPRAPWVTIDGGLNHA
DELVALASEFGDFTVGVAAFPDGHPASHGNLDKDIDVLIRKEDLGASFATTQFFFDASKW
SALVARLDERGSKLPVIPGIMPVTNVKQLVRMSELTGTPIPDAMRKKFEAIESDADAVRA
LGIEIATEFCQKLLSAGAPGLHFYTMNTSTATSQIYENLALKR
>A0A2Y9FZH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichechus manatus latirostris|TrEMBL
MVNEARGDGGPSPSSDGGSSSGSESSKDSSRCSTPGLDPERHDRLWEKMRRRMESGDKWF
SLEFFPPRTTEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCHQSREEITGHLHKAKRLGLKNILALRGDPIGKQWEEEEEGFSCALDLVK
HIRSEFGDYFDICVAGYPKGHPEAVSFEADLKYLKEKVSAGADFIITQLFFEADTFFRFV
KACTEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQTIKDVIEPIKDNDAAIRSYGIE
LAVSLCRDLLASGLVPGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKM
WGEELTSEESVFEVFAHYLSGEPNRNGCKVTCLPWNDEPLAAETNLMKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKRYELRVNYHI
VDVKGENITNAPDLRPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYE
EESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPAPE
>A0A374Q8F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. 4_1_36|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIREVAKQIY
>A0A174RGX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi|TrEMBL
MKIKDILGQGKPTLSFEVFPPKTEDKYESVERAAAEIAKLKPAFMSVTYGAGGGTSRYTV
DIASTLHHEYQVTALAHVTCVSSTREKVHEVLEELKAAGIENILALRGDVPKDGPVASDY
RFASELIREIRAYGDFCIGAACYPEGHVESVSKTIDMDYLKQKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVVAGIMPVTNVKQIIRSCQLSGTYLPSRFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANGVDAIHVYSMNKPDVAAKIKENLSEILS
>A0A2D9E056|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leeuwenhoekiella sp|TrEMBL
MKITDHIKNANGKTLFSFELIPPKKGKSIQELYNNIDPLMEFKPPFIDVTTSREEFVYIE
KDGLLDKKVTRMRPGTIGICASIKHKYNVDTVPHVLCGGFTKEETEYMLVDCHYLGIHNL
MALRGDAMREEQYFKPTPGGHEYALGLVEQVAEMNKGRYLNGMVETSDCSDFCIGVAGYP
EKHLEAPSLKTDLKRLKQKVEAGADYVVTQMFFDNKKYFEFVDLVRAEGIDIPIIPGIKP
IAVKRHLQLLPQVFKIDLPQDLIDSVEACKTNADVRQVGVEWAIQQSKELMEGGAPVLHY
YSMGKSDNVKAIASELF
>A0A7T4VLH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzae|TrEMBL
MPSHTRAITDAYSLEVSVKDIGALTKAAPRLLPGSSMFIPYLPGQHDAARLAAAQLVRSL
GFEPMPHLSARRIGAPEELQAFVARLVDEAGVTRCFVIAGDPSTPKGPFADSLSLIETGV
FERSGIRTIGVAGHPEGHPIMRTAEQWDVLERKCRRIQERGMAPLIVTQFGFDADMVVTW
VEALRARGIPHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGNAGPDR
FVDRLASRLTDAHGDIRLHVFPFGGIGQSVAWMAQYRSRASSQDRMSSVHADQA
>A0A418UQE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. 2119|TrEMBL
MDRVDRVDQYDADLVPVTGPPLPAAGPVAPQRAASPGAAGAALAPAGLPSLSLELFPPRP
GVHASQTWGALDRLLGVLPDFVSVTYRPTFAPDPDGGPGVCAVREHNPAEDVVTHVLATS
RVPLMAHLTCIGYRRRDVVEIVRLFLGLGVRRFLALRGDPPRGTRASDVPGELRYASDLV
RVIREVEDEYFGDGARHLQVAVAAYPACEDLEAEVEVLAAKQEAGADLAITQVFYDAQDY
LSLSRAASYSGVVMPVLPGIIPLTDLRRLTRLESLTGVQVPADLSATLRRAEGAQAVAAG
IDATLRLATQVLDGGAPGVHLYTFNRTRPALDVVSHLRLGGIFRGQEPDRETQHEVDLAY
LNATPGGDRRPSVW
>A0A3B3TWG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poecilia latipinna|TrEMBL
MVNQVQQVDGSWQSCRGDSSGTSNSSTESSKESSRCSTPLLDADRSDRLREKMRKRMESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITSYLAKAKHLGLKNIMALRGDPVGDDWEDEEGGFNFAV
DLVKHIRSEFDDYFDICVAGYPTGHPEAGSYEQDLQHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAVGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKIIEPIKDNDAAIRN
YGIHQAVDMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWVEDPRRPLPWAVSANPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LVQMWGEELKNEQSVFEVFTCYITAQPNRNGQKVLCLPWNDEPLAPETNFLKDELEKVNR
RGVLTINSQPNINGKPSADPVVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGHNMTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWHVIDDMFELLDSTPEPLTDEAGS
Q
>A0A4Q5HW30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEAQINDFNKGVFVDGSPIKITGTPFSYGVTCYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVEKVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A3Y3U245|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1S4DQY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nicotiana tabacum|TrEMBL
MKVIDKIHESAKTDRVVFSFEFFPPKTEDGVDNLFERMERMVSHNPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGIATQETYENDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHQATEMCKKILATGIKTLHLYTLNMEKSALAILMNL
GLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDEYPHGRWGNAQNP
SYGALSDYQFMRARSRDKKLQEEWAVALNSVEDIYERFMNCCLGKLRSCPWSELDGLQPE
TKIIDEHLGNINTKGFLTINSQPAVNGAKSDAPSIGWGGPGGYVYQKAYLEFFCSREKLN
ALVEKCKAFPFLTYMAVNKEGNWISNANQTDINAVTWGVFPGKEIVQPTVVDPASFMVWK
DEAFEIWSRGWAQLYQESDPSRKLLEQVQNSYFLVSLVDNDYINGDLFAIFKDI
>A0A081GVG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLDKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A3F3L573|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter ursingii|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKIVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTAVAPHLSCIGDDKGRIAKLLDLYQSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAETFDADIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERLEKEGITIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A5T1JCL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEIEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALVGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A736VB73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. houtenae serovar 45:g,z51:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A081PWE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A119KK63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cepacia|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLMPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLVDAGVPGLHFYTLNTAAATRTICERLDV
>A0A848TGU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Silicimonas sp|TrEMBL
MSEPTVSFEFFPPKSLDASFQLWEALRSLRHLDPAFVSVTYGAGGTTRELTHEAVETIRD
HTGVEVAAHLTCVNASKDETLEIAQRYAAAGVSKIVALRGDPPDGSEAFEAHGDGFASSV
ELIEALASVGTFDIIVGAYPDPHPEAGYEDADVDWLKRKVDAGATSAITQFFFEAETFLR
FRDRCDAAGIDIPVLPGILPIQSWNGVRRFAERCGARIPDTLALAFEAAERDERSDLLAL
TQCTTLCTRLLDEGAGHLHFYTLNKPDLTREVIHALGLAPAAVLENVA
>A0A0H4LDJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus farciminis|TrEMBL
MTETNPTLSFEVFPPNSQVGVDNLTDTLDQLKGLNPSFISVTASNHKLNYEETTINLAKY
VKDNLHCHTMVHMPAAYVTKTEVRSILNRLEKMNIHQVLALRGDIVEGYVPEKDFKYASD
LTQFIKQEKPDFTVSGACYPEVHPDSKNRIDDIKHLKNKVDSGCDQLITQLFYDNEQFYR
FQEECAIADINVPILAGIMPIVNRKQALHVIENCAARLPKKFINILDKYKDNPVSLKEAG
IAYAVDQIVDLVTNDVSGVHLYTMNKADTAKHIFKNTASLFHLDGVTE
>A0A831J0Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKDGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVEAGADYVVTQMFYDNRKYVDFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAMKCKDDKEARALGIEWCINQCRELIAYGVPGIHF
YTVGAVDNVKEVATAVY
>A0A3M7AKU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGIRNILALRGDPPRSDE
YNDPNNPLSEQDDSNRDFTWAVDLVRYIRKQYDDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLVEKTAAGADFIMTQLFFDVEAYNDYEKRLRSHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLSRMEPIKADDEAVKRVGVDVLCEMVENMRRRESPCARGFHFYTL
NLEKVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVENAKRNRQRRKSS
NRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPVNSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLQGEIEA
MPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSNDPIYGWGPKNGFVFQKPF
VELFLPSADWQRLKPILQADDQVTYYAGNAAGDFQSSDENSVNPVTWGTFAGKEIITPTI
IEGDSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDA
LIAA
>A0A2I1QYQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria perflava|TrEMBL
MNHAREIAALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHSIVKRIKQETGLDAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVMMGIDVEIVPGILPVTNFKQLTKMAQVTNVKIPSWLSKMYEGL
DNDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRPR
>A0A535YLB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSTFTQLLRRGDFVVTAELNPPKSAAAQVVRRRASILKGYVDAVNVTDSNRAVAAMAAIP
AAVIAREAGVDPIVQITGRDRNRIALQADVLGAAALGIEHFVFMSGDDPKQGNHPDAVNV
KDLDGIGLVKMAASLRDKAQFLSGDEIKEPPQYTIGATASPFTKPMESDLRKTTEKIAAG
ADFIQTQPVFDLATFSQWLAEVRRLAGRHVAILAGVLVLRGAEQAERLAKVPGLALGTHV
VERIRAAEDQEGEGIAIAVETAKSLRSLPGVNGIHLYAIEWPQGVTKVVRAAGLYPRPLL
KESKSA
>A0A0D2XCQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936)|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIISELIDRIKAIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDPVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A536PZM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVRPLGAQSVGQALAGLLRTPRYEIFPTDGVVELVTAHVPKEVTLTVTASPRRGLPATVV
LAARLSRLGYRAVPHLSARLIRDRVELGQILDALKAAGIRNVFVVAGDASEPAGQFPDSM
SLLAALPPDHGLTEIGVTGYPESHPFIHDDVTIQSMWDKRRLATYIVSNLSFDPATIKRW
VERVRRRGVQLPIYIGMAGVADPARLLRLSTRIGMAESARFLRGHPSWLARMFRPGGYAP
GRFVSALLPDLAQPDRRVAGLHVFTFNEIEPTERWRQEMLARYAQEVV
>A0A507CHL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synchytrium endobioticum|TrEMBL
MKIIDKLHAKLQDDKCHWSFEYFPPKTEQGVLNLYDRLERMYKLGPEFIDVTWNAGGSTS
DLTLDICATSQTVYGLETCMHLTCTNMPKEKVDIALKGAKDAGIQNILALRGDPPRGQEH
WEAVESGFSHASDLVTYIRQQYGDYFCIGVAGYPEGHLDNPSRDDDIERLKYKIDCGSDF
IITQMFYDVDVYLTWLKDCREAGITCPIIPGIMPIQSYGGFQRMTTLSKTIVPDFIQEAL
EPIKDDDAAVKEFGINLSVQMCNQLRAAGVRSFHFCTLNLEKSVRRILEGLNFYCEPEVV
KPLPWVPSLAKGRQNETVRPIFWANRTKSYIMRTESWDDYPNGRWGDSRSPAYGDLDGYG
VSLKYSHDECREMWGHPASKEDIYKLFADYCRGRLKALPWSESPLAPESSRIRDYLTRIN
EIGCLTINSQPAVDGAPSSDRFVGWGPKNGFCYQKAYLEFFVSPEALDVLIKQIASDPYI
TFYAVNRHGDLRTNTKSDGPNALTWGVFPGQEIVQPTVVEAVSFMAWKDEAFELWGRWAH
LYEPGTASSTTIQEIADAWFLMNVVHNNYKVQEAIFSIFDGLTHSALHVNGR
>A0A2I1DRJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus irregularis|TrEMBL
MKITDKINNNLETSQPFYSFEYFPPKTDEGLNNLYDRLKRMSHLDPLFASFTWGAGGSTI
DRTTEMCATAQSLYGLESCMHLTCTNVVRGTIEKAMKEAKSAGIQNILALRGDPPRGQEY
WTSCDSDFTHAIDLVRFIRKEYGDYFCIGVAGYPEGNPDSENKEQDLKFLKEKVDAGADF
IITQLFYDVNTFVEWRDECRKNGINVPIIPGIMPIQGYNSFRRITNLCKIHIPAEILNVL
EPIKHDDQAVKDYGVTLAVSMISKLRNEHNTRGFHLCTMNLEKSVRLILEILGFVQTEEE
RNLRRLSRRRSSAGFGPNDIIRQEPDGSLPTAKPVIWKERSVDYLGRPEDWDNFPNGRWG
DARSPAFGELDGYGVSLRIPPEQALGYWQRPMTLDDLKQVFKSYILGEIPALPWYEEPLY
AETEAIRSKLVHLNELGFLTVSSQPAVNGARSDDPIYGWGPRGGYVYQKAFVEFFVSPEN
FEELVEKIKGNPWVTYCASNRNGDFRSNTKDDSPSAVTWGVFPGKEIVQPTIIAKVSFNT
WKDEAYALWTEWEHLYPKDSPSQRLLKDIGDNWWLVNLVYHNYVNSEEIWEIFFKS
>A0A536F1U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSPSRLAGLLRDGHFVVTAELSSSNSADPQATWRRAEVLRGSVDAINCTDNTGAHVHMS
SLAAAHLLVEKGLEPIMQLTVRDRNRLALQADLLGAAALGVRNLVLMSGDDVTAGDHPEA
RRIYDIDSMQLLEVAAAMRDRGTYLSGRKLEQAPSFFIGAVENPFAPPLEFRPLRLQKKV
RAGADFIQTQLVFDVPVFTRFMDMVGELDLQQKVFIIPSIGIPRSARGARFMQQKVPGLH
VPESLVSRLERTAPARQAEEGIQIAVELVRAVREIPGIAGVHLIGIKWEEGVVQVAERAG
LLPRPTLSPLAAIGIVHSPAGGGQGGGVP
>A0A3R6DEB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides merdae|TrEMBL
MKVIDLINSSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSFQKINIRKRPGSVAIASAIQNKYGITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQKTDIYHEHATDLQKQVNDFNKGIAIDGSAFEANETPFSYGMACYPE
KHEEAPNMDSDIFYLKEKVKNGADYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDDEAKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVYKVAKEVY
>A0A354MMI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides merdae|TrEMBL
MKVIDLINSSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQKTDIYHEHATDLQQQVNDFNKGIAIDGSVFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDDEAKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVYKVAKEVY
>A0A6D0IM07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
SAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMD
MVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A139Q7B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A6G4HMY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIKNILALRGDIPKDKDIIGE
YNYAFELIEKIKASNNFGISGACYPEGHIECKSLDQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQQKSINVPIQAGIMPVVNKKQIERIVKISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVNLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDIAV
>A0A0B8QP67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis|TrEMBL
MTSNSKILSFEVFPSTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFRFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>A0A1Y6GPI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella ornithinolytica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAEDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A502INB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus laterosporus|TrEMBL
MGKRDLRAYLTQHLLVGDGAMATQLYEQGVPIGVSYEELCLSNPQVIRNVHAAYYEAGAR
LIETNTFGANRDSLSRYGLESKVTRMNRAAVTIAREAVGDDAFVVGAMGSIIAGRVRNKQ
IEQYRDQFEEQATSLLHAGVDGILLETFLDVDELLLALDVIRPITQLPIIAQLATLEVGT
TRDGHMLTSAFQLIKDAGADVIGLNCRLGPAEILRSFEATVCPNDVYLSAFPNAGRLGMA
DGTLSYKSSPEYFAESAVRLREQGVRLIGGCCGTTPEHTRAIAEKLAGVTPLPRVNPQAP
IHSETITVPAVQQRLQPSIIDQVKHHPTIIVEFDPPKDLHTEDFLHGCCALHEAGANAVT
LADNSLATVRMSNMALGAMMKRLGVEPLLHIACRDRNLIGQQSHLMGLHALGIDQVLVIT
GDPSRFGDLPGASSVYDVSSFDLIRMVKQLNQGFAFSGKQLKQNAQFIVGAAFNPHVRHL
DAAVARLEKKVEAGADYIMTQPVYDAETIVHIYEATKHIHVPIFIGIMPLTSLRNAEFLH
NEVPGIKLSTYALEQMKLFTGEAARQEGNRMAKELIDVTLQYFNGIYLITPFNYYQMTVE
LTQYIRQQEQVKAGYKQVSSS
>A0A351HT66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinilabiliales bacterium|TrEMBL
MKVIDLINNRKKTLFSIEIVPPLRGNKVEGIYQRIEQLIEFQPAFINITYHKDEATYSQL
KNGKIIKRTISKRPGTVALTASIMNKYKVEVVPHLTCGGFSRDQAENALIDFNFLGIENL
LVLQGDAGRGQDVFIPDPDGHRYAVELVEQVMNMNKGKYLDENLEQANPSNFCVGVAGYP
EKHYAAASLESDIQYLKAKVLAGAEYIITQMFFDNKHYFDFVQKCRAAGITVPIIPGLKP
IALLDQVEVLPRLFHLEIPEDLKKEIKKCKDNKEALEVGTHWSIEQAKELINQGAPVLHF
YTLGAGSSIRKIAEEIF
>A0A3Q8SUZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus|TrEMBL
MSLTALFKNKTVFSLEVVPPKKDSPKEAILPTLQQLQSINPDFISVTSGAGGSDHYTGTV
QIADLIQNQLNIPAVAHVPGLYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDF
NHANDLVAFVHQNRPDFSIASACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDN
QAFYDFQEKAEIAGIHVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSKEA
MREAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTMNYT
GTEVPGFWEH
>A0A2S9RS42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>I1KG04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycine max|TrEMBL
MKIIEKIHAASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVVHNPSFCDITWGAGGTT
ADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVQHIRAKYGDYFGITVAGYPEAHPDVIESDGLATSEGYQNDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGINTLHLYTLNMEKSALAILMN
LGLIEETKVSRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALSDYQFMRPRARDKKLVEEWAVPLKSIEDIYERFRLYCLGKLRSNPWSELDGLQP
ETKIINELLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKL
DALVDKCKDRTSLTYMAVNKDGSWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFNVW
KDEAFEIWSRGWASLYPEGDASRKLVEEVGF
>A0A1C6FI94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MSLLKEALENGKFAVTAEMAPPKGTDLSHLIECAKAVKGRVHAVNVTDFQSAVMRTTSLT
TCKLLKDEGLEPVLQVTGRDRNRIAIQGELLSAGVFGITNMLALTGDHTIVGDHPQAKPV
FDLDCVGILKTAQKLSQGTDMVGNQLKGAPSFYLGASVTPRYTPIEIQLLKMKKKINAGA
KFFQTQAVYDIDTMREFRKHTKDMNTKVLAGIIPLKSPGMAKFMNANVPGIYVPDELIER
LRAVGKENWVSEGIKIAGELIQQLRNEDLCDGVHIMAIGAEENVPAILDAANI
>D3PMT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meiothermus ruber (strain ATCC 35948 / DSM 1279 / VKM B-1258 / 21)|TrEMBL
MKVSTLLQSGKPLFSFEFFPPKTPRGEAALFRTLHELKPLKPAFVSITYGAGGSERNKTA
EWAARIQNEVGLPAMAHLTCVGSTREELLARLHEYARAGVENIMALRGDPPQGAREFQPV
AGGFRYAAELVALIRAEFGDRFTVAGGAYPEGHIEAVSLEADLRHLKQKVEAGLDFVVTQ
LFFNNALYFGFVERARRIGIQVPIVPGLMPITDLAQVRRFMDLCGASIPGPLLSRLERAQ
SPEEVLEIGVEHATRQAQELLEAGAPGLHLYTLNKSPATRRVMQNLQMVLR
>I1KG02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycine max|TrEMBL
MKIIEKIHAASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVVHNPSFCDITWGAGGTT
ADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVQHIRAKYGDYFGITVAGYPEAHPDVIESDGLATSEGYQNDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGINTLHLYTLNMEKSALAILMN
LGLIEETKVSRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALSDYQFMRPRARDKKLVEEWAVPLKSIEDIYERFRLYCLGKLRSNPWSELDGLQP
ETKIINELLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKL
DALVDKCKDRTSLTYMAVNKDGSWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFNVW
KDEAFEIWSRGWASLYPEGDASRKLVEEVGGSYFLVSLVDNDYINGDLFTVFADF
>A0A6J7U585|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSQDLRTTTFSLEFFPPKDVAGEERLWQALGQLQPLKPDFVSVTYGAGGSTRDRTIRVTT
EITARTSIPTVAHLTCVGSTRSELIEILKQYKSAGIKSILALRGDPQSGPRGVWQENIDG
FNHADQLVELAIQTGDFKVGVAAFPDGHPASNFNFEKDVDVLIRKEELGATFATTQFFFE
VSKWQKLVDRLAKRGSTLPIIAGVLPITNLKQLNRMSELSGTQVPDEILKHFEGKEDNPE
EVKKIGIDIATSLGEKLLELKAPGIHFYTMNSSESTVAIAKNLGLIKP
>A0A6J7L0T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MPPASGFGSSVSTISELLSLGRHSFSFEFFPPKTDDGERLLWQAIRELEPLRPTFVSVTF
GAGGSTRDRTVRVTRRILEETTLVPVAHLTCVAASIAELRSVIGEYADAGLRNVLALRGD
PPGGPGTPWVQHEGGLEHADELVALVRSLGDFCVGVAAFPEGHPESTSRDDDARVLLRKQ
EAGAEFAITQFFFRADDYFDLVERARAAGCTIPIIPGLMPVTNLSQIERFSVLSGAAFPA
ELATRFRALGDDAAAVHALGVEVASEMAAEVLAGGAPGLHFYTLNRSTSTREIYTGLGLS
AFA
>A0A0P9SCG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. glycinea|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A174EM50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ruminococcus] torques|TrEMBL
MKIIDRLKEDKIHISFEVFPPKTDAGFEKVIAATDAMAKLNPAFISVTYGAGGGTSKNTA
KIASHIKDDLGVVSLAHLTCASSTIEEVRDVIENLKENGIENILALRGDIPEGMPFPNGN
RFRYAYELIEEIRKHGDFCIGAACYPEGHVENEHKAEDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGINVPVLPGIMPMTSEKQMKRSQELSGTVFPRRFLALLDRFGSSAA
AMEQAGIAYATDQIIDLLSNGVNNIHIYTMNKPHVAAAIMNNLSEIIKA
>A0A6J6UC53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSADTAPTISFEFFPPKDTVAEENLWNAIADLQQYQPDFVSITYGAGGGTRDRTVRIASD
FIARTGVPVIGHLTCVGSTRNELKEVLEQYKSEGFHGVLALRGDPVGGPTAPWVTTPGGF
DFADQLVALAADVGGFSIGVAAFPDVHPASDGNFVQDVNVLLRKEELGATFAITQFVFDS
GRYEALRNALDQRGSKLSIYPGIMPVTSYPQIVKMLELSGGYMPKATRLRFARYQNDAVS
LKKLGIDVAVQICEDVFALGAEGLHFYTLNNAGPTGEIIKQLSMLSR
>A0A6J6U9Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSKLRDVITQTKDVVYTAEFPIIDGGGMEQVKKNVERLAPWFVAVNATDNTAAHAHASNV
SVAIAMKQHGLEPIMQIVCRDKNRLAIQADMAGANLHGIENIALLTGDDVTAGDEPETRR
VFDLDGPQAINVASILNAGTYLSGRKLNPAPNFFICSVENPFAPPHDYRIERVLKKHRAG
AQMIQLQIGYYPERLEKFCAGVAATVPDLAIIPSVVLIKSAKPLSFMNDKVPGISVPQDV
IDRVAQSTDQAEAAYHLALEQCQHALALPGVRGLHITDFRHDDTLERLMRDLGRTPNQYT
>A0A6J7FDF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSSTTFSVEFFPPKDSDGEERLWAAMADLRALAPDFISVTYGAGGSTRDRTVRITKEITE
KTGIATVAHLTCVGSTKSEIVEILGQYKEAGIKSILALRGDPSQGPSAPWVSTPGGFDHA
DQLVEIAAHTGDFTIGVAAFPDGHPASAGNLDRDVDVLLRKEELGASFATTQFFFESAKW
IALVERLQRKGSSLPIIAGILPITNLKQLKRMAELSGTPIPTKIEKAFLDLGDNPSDVAK
LGVELATHLCDELLDAGVPGLHFYTMNTSSATVDIAKNLGFDSRATR
>A0A657Q0H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sedimenticola endophacoides|TrEMBL
MKSQEPFTKTFSFELFPPKTGAGMEKLQHNVRELSRLDPLYFSVTFGAGGSTRERTFDSV
QWLASEGLDTAPHLSCIGSTRSEIVEILDQYKAQGVRRVVALRGDLPSGAGLGGLGELNY
ANELVGLIREEFADHFHIEVAAYPEFHPQAPNANADLKNFMRKVEAGADGAITQYFYNPD
AYYRFIDSCEGMGLAIPVVPGIMPITNYSSLMRFSDACGAEIPRWIRKRLEAYGDDIESI
RAFGIEVVSGMCEQLLAQGAPGLHFYTMNQSVPTLRICANLGLSPAR
>A0A2A3N594|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sputigena|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYQNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
IMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVEACKNNADVKQVGIEWAIQQSKELKAAGAPVLHY
YSMGKSDNIVKVISEVF
>Q5L8K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow)|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A442FVF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDTVIREFVDFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>A0A442VWJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRLSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVAAAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
GSAAA
>A0A439U2H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMETKLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETAVPAAAHLTCVGATRDEVDAVIHDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A442S5G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGG
PYRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>N4W0R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422)|TrEMBL
MDKITDKIAALPADANYFSLEFFPPKTQMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRTLIDKALEDAKALGIRNILALRGDPPRKDE
YRTADDSDVEDMDDFVWAIDLVRYIRKKYGDYFCIGVAAYPEGHADESHPLGQSFEHDLP
YLVDKVQAGADFIMTQLFFDIKAYDNFERVLREHPSGAFKTIPLLPGLMPIQSYQMIKRT
TKLSHAKVPADLMARLDAAKGDDERVKRVGVDILSELVQQVREVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDADEDEEAVIDDAIGVPTVQLNGLSPIPPSTPRTFSGRRQSSIG
SDPHNRVIVSSASNPAYETTAASLSAEPVNTRANTLAISEGEGVLGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHMSVTQAVGLWGTPKTVQDVNNLFIRHIKGQLSAIPWSEEELL
PESNIIQQELLGLNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVEFFLPSAD
WASLVARLNEVTDNTICFYAANAAGDFVSSDASGGLVLEGTECSTNAVTWGVFPGKEIIT
PTIIEEVSFRAWADEAFKIWGEWAKVYGKGSESEALLERIQSDYWLVNVIHHDYVERDAL
WQLLNGEKET
>A0A0N1MPZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter pullorum|TrEMBL
MNKIENFIQILKSNEKCFTYEFSAPPSFSLDTFFDALQQENLVSKIHAFICTDSPLAKLK
HNAILASLKLQNAFNLPSITTISMRDRNTLAIQSELIGMNSLDLRLILALTGDPIRHGNQ
PQAKGVFEGNSLLLLKIIQQLNQAKDINNHPIQGDFKPFYAFSVLNSYSNKKENLYKKMQ
EKIQNGASAIITQPIYDLDIAQELLQWCDKINQESSTNCTLIFGFFPITSYKTALFLHNK
LPGVFIPQSWLETMEKASHNNTELEIGLEKSQRLFENLCKIQAKIHLMSSNKVDIIGKIL
NGR
>A0A0H4W7R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella hinzii|TrEMBL
MTDSTSPALSLEFFPPRDIAAQERLVRAAKQMLAIRPRYVSVTFGAGGSTRAGTEETVRT
LTNLGCDAAPHLSCIGASREQLREILNHYREAGVHRVVALRGDLPSGMGGDAGELRYASD
LVRFIREETGDWFHIEVAAYPEMHPQAASPTADLDHFVAKVQAGADAAITQYFFNADAYF
DFVDRAQARGVAIPIVPGIMPITNYSQLSRFSEMCGAELPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGVPGLHFYTLNQSEATLGIWKNLQL
>A0A6G1G1T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eremomyces bilateralis CBS 781.70|TrEMBL
MHISERLRAAEEAGRPSISFEFFPPKTAQGVQNLYDRMDRMHDLGPTFIDVTWGAGGRHS
GLTCEMVKVAQSVYGLETCMHLTCTDMEKSKIDDALKEAYNSGCTNILALRGDPPRENEK
WVASQGGFQYARDLVKYIRSQYGDHFDIGVAGYSEGCDDNKNTDELIRHLKEKVDAGGTF
VITQMFYDTDIFLDWLRKVREAGITVPIIPGIMPIHTYGAFIRRANWTECNVPKAWMEAL
EPVKNDDAAVRDVGRELIVEMCKRLLAGGINHLHFYTMNLAQATRMVLEDLNLVPDLESP
LEKPLPWRPSKGLKRREENVRPIFWRNRNRSYVVRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEANVKLWGEPSTIRDISNLFVKYMQGKLDHLPWSENPLSLESDVLRGELVD
LNTRGIFTINSQPPVDGEKSTHPVYGWGPRNGYVFQKAYLESFVSPEMISELITRIERNP
DMTYYAVNKAGELKTNAPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQDW
ANCYSATNQSRYVIEDMMDTYYLVNIVHNDFRKTEGIFPLFDGLGLQDMEKLIHAVDKGI
ATVDGVSDTLTNGDVKGQPNGHPPALANGVR
>A0A7Y2FMA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MRIADLYAANVGPVYSLEFFTPKNDAGRNALFRAVERLQAMKPGFVSITCGAAGTTRERT
ADLAIELQKEFGLTAMAHLVCTGTTQAELEGTLRHMRAHGIDNILALRGDPPKGATDWTP
VEGGFAHANELAAFVRERFSLGLGGACYPEKHHEASSLAADIQNLKLKVEAGAEFLITQL
FFDNDKYWSFVERIRAEGIEVPVVPGIMPVLNLTNLQRIASLSPGTSIPAELEDALREAG
DDDDVALRAGVRFAAKQCRALLANGAPGIHFYTLNRSKATLQTFARL
>A0A7C7U7J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MNIVDLYRHGDPVISFEFFPPKTDRGYHALFETIGDLKELTPGFVSMTMGAGGSTRSQTV
DLVIRIERELDLTAMAHLPCLGSERAEIAQVLDDLAVAGIQNVLALRGDPPRDTTDFRHP
DDGFDYASELTAFIAERGGFSIGGGCHPETHPEATSAETDLMNLKKKVDAGAQFLISQLF
FDNTKFFAFVDRARAEGIQIPIVPGIMPITSVSGIRRMSALGGGTIPSELDSELSRNDED
DAAVLEIGIEWASLQCRELIEAGVPGIHFYTLNRSSATRRIHRALREAGLVQ
>A0A3S6Z6T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfobacillus thermotolerans|TrEMBL
MKSLADALRDPTWIIGDGASGTALMAAGIDPAALPLVPLRQPDTLMNLHLQYLEAGARLL
ETQTFSANGSKLAALGLEADVVLLHRRAAQIARHARDIFGEPAWIVGSIGPLAQPVASPV
MESLTHEEAVDYYRPVVAGLLAGGVDGFIVETMSDIPTVLAAVEAIREESLLPIIVSFAF
SPEGATRYGLTPEQAIEAMGQLPGGPPQLVGANCGSGPAPLLDAVIRMAPRAKDLQIPLA
AFPNAGQPAMVANHVHYPASPHYVATMAPALAEAGCRVIGGCCGTTAAHIQAIAQTLQHM
PVLPQVRTWNVEDEHAANETMGSEGAPEGIRQLFGKRFVVSVELDPPRGVNPHRVLEAAR
TVWEAGADAINIGDSPMARVRLSALATARLIAEQLPVETILHFTTRDRNLMGLQSDLLGA
HALGIRNVLALTGDPPGIGDYAHATAVYDINSIGLVKVLAGFNQGQDASGQKIGGHTAFD
IGVGVNPTAEDLDHEVLRLQQKLEAGAGFIMSQPIYAKEQLERFLDRFGPLPVPLLLGVM
PLVSYRQALYLHNEVPGITIGTEILAQFEHVQDGTALGIDMACALLDDLESVIQGVYLVP
SFNRVEPLLPLIAYIRQKFSTKKRS
>A0A5C0A6R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter thailandicus|TrEMBL
MIRSIGQVRTNLMTESSIELLPSRILELSGVLPDLDRGSRVFVTWLPGVPFADVLAACDL
LKLCGYLPVPHVAARSIRDTQHLRNICTALIERDIPRMLLIAGGADKPAGTFTDTVQVLE
TEIPAQAGIRTVYVAGHPEGHPQATEKQLEQYLLRKQELARAQGLNMQIVTQFCFDAEPV
LNWEKRLRAAGVRLPINLGIYGLTTPRTLVRYGLACGVGQSLRFMQKQRWKLHRWFTPCN
PKDLVDAIAGSIAETPDTLFHGLHFYPFGAIARTLEWRRNFSCSTYGEPS
>K8DEQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter sakazakii 696|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDIVPDELRTIARDYWNNGIRHIVALRGD
LPAGSGKPEMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPALELKT
A
>A0A0L0V4U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia striiformis f. sp. tritici PST-78|TrEMBL
MKKVVELIECLRDDEVYFTFEYFPPKTIDGLSNLYARIQRMANLKPSCAHVTWGASGSTS
DTSLEIAAMVQDQLSIPACLHLTCTNIQRSHLDQTLSQAKESGIVNILALRGDPPRGTEN
WIPTDQQFQHAIDLVKYIRKEHQTHFCIGVAAYPEGTNDFDQDQELDYLKQKVDAGADFI
VTQLFYDVDFFLNWVKACRKLGINVPIIPGIMPIQSYEGFRRLTALCKTKIPDSIHAKLI
PIKGDDQAVRDFGVELSMQMIKLLRVNGFKSFHLCTLNLERSITRLVSQLGWAPGRGNKQ
CQSLLGPGAKMGTADIVQGGLSVGWDEFPNGRFGDQRSPAFGLREGYSSSLTSAFSHLTT
DVHALWGTPTSLEDITNIFCAFTQGKLHSTPWSEEPLALETTSITPFLAKLNQNGWWTVG
SQPAIDGVDSLDSVVGFGPEGGRVYQKAFVEFFIPKSHLEGLLSAVGEYNKDHPEGVAQL
RYYAGNCNQDQIRTNMALGETNAVTWGVFRGAEVVTTTLIEAQSFKTWKKQAFDIWNDWA
ESFESGSANQRLLNEIEDSYWLCSMINHDFKQADHLWSFLINHQQRLLAEQS
>A0A1E4A5N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagaceae bacterium SCN 52-12|TrEMBL
MLRSKLENNESGILLYGITPPKSGHDPEKIRAIAGRQQKRIESLDIDGLVLYDIQDESSR
NSQPRPFPFIETIDPWTYSREYLGGLNLPRIIYNGVGRYTPGTFADWLRLQGADLDLMVL
VGSPSRQSAAGLSLHDAYNLKRALGSPVLMGGVTIPERHARNTDEHLRVVSKTLAGCRFF
ISQCVYNVRNALVFLTDYCRLLDETGEKPVPIIFTITPCGSMKTLHFMEWLGIEIPASLR
KELEMSSDMLERSVEACRDIADELVSYASSLCVPIGFNIESVAVRKDEIEASLELVKYIK
DKSFKASRTVSG
>A0A4Q7B2A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter junii|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQNLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIQRFVEKVQAGANAGITQFFFNPDAYFYFI
ERLAKSGINIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>C3XBX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacter formigenes OXCC13|TrEMBL
MPTQKSFSIEVFPPKTPEGIEALRKTRAELAELSPKYFSITYGAGGSTQQGTHNIALEIQ
KEGFEAAPHVTCIGTTRESVRERLNECRANGIRHIVALRGDLPSSYGVLGEFRYANELVE
FIRAETGDWFRIDVAAYPEMHPQAKSLQDDVDNFVRKAQAGADAAITQYFYNASSYFRFM
ENVQKAGVDIPVIAGIMPITNFKQLAQFSDMCGAEIPRWIRLRLESYGDDLASIRAFGLD
VVTELCEQLLAGGAPGLHFYSLNKAATTREIWHRLKLDERKEIGSDKKAEAVQV
>A0A1Z4ND47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix sp. NIES-3974|TrEMBL
MTGLYAIAVPRVHSLDVMADTSNFLSSISFRDAARNGDFLITAEVAPPKGGNPEHMLRMA
ATLKGRVHAVNITDGSRAVLRMTPLAASAILLKHGIEPICQFACRDRNRIAMQADLMGAH
ALGIRNILALTGDPVKAGDHPNCKGVFDLEAVRLLQVIQKLNLGVDFNDKPLTDGELDLF
PGAAVDPQCSSWSGLQSRFEKKLAAGAQFFQSQLITDFDRLQKFMDGIAAGCNKPILAGI
FLLKSAKNAEFINRMVPGVNIPQDIIDRLAAAPDPLQEGMKIASEQVQFAKQLCQGVHLM
AVKREDLIAPILDMAGIAPIGKVYAQVDGNF
>J3K8E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccidioides immitis (strain RS)|TrEMBL
MEKISNKIAALPEDANYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT
ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPPRSDE
YNLDGEDDSNKEFTYAVDLVRYIRKKHSDYFCIGVAAYPEGHSDESHPGVQDPVRDLPYL
VEKTKAGADFIMTQLTYDLEAYKRFESMLRNHESGVFKTIPIIPGLMPIQSYPRLTRITK
LSHVRVPPEMLSRIEACKKDDEAVKKVGVDILSELVEGIKTIPGTGPRGLHFYTLNLEKS
VSFILERCNLIPPSSEASSDTDSDSVFASGNLQNGLGTAAGKPPLISRRRASSLNSQPHN
RVIVDRADISSQSSITHEASAQGAGMPALNPPHRNTALQISEGMGALGREATWDDFPNGR
WGDARSPAFGEIDGYGPSLHVTANVARRLWGYPTTREDINNIFRQHVSGGLHAVPWSEGG
AAEETGGLSPETITIRPYLLSLIEKRGWWTIASQPAVSGVRSDHPIFGWGPPGEGFVFQK
AFVEFFCSKDDYRSHLKPLLQRYGHDEFAWFATNAAGDFESSTSSSIPVPTGPVDAVFDD
MDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWDEWRRIFPRGSPT
EKLLNRVKEDTWLVCVIGQRFGAGGDPGKDAMEEGKILWKVLAGENVSLQS
>A0A1B9EJM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PTY087I2|TrEMBL
MALGIPSTRPDRAATIRDLLDSGRRSYSFEFMPPRTAEAEAGLWRAIRKLEALSPTFVSV
TYGAGGSTRGRTVNVTGRIAQETTLTPAAHLTAVDHSVAELRNILGHYADQGVRNILALR
GDPPGDPLGPWRRHPEGVAYAADLVRLIKESGEFCVGVAAFPEMHPRSSDWDSEIRHFVD
KCRAGADYAITQMFFDVETYLRFRDRLASAGCTTPVIPEIMPVTTVRSLRRIPSLSTAAF
PQRLAERMFAAEDDPKAVRALGIEHATGMCRRLIDEEAPGLHFMTMNFSQVTTEIYRNLG
LQSR
>A0A429XCZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Siminovitchia terrae|TrEMBL
MNLLDSLKERILIGDGATGTLLYSYGIDRCFEELNLTHPDGIFHIHEEYLKAGAEVIQTN
TYGANYIKLNRYGLEERVKEINSEAVKIARRAAKKDAFVIGTIGGIHGARFHSELSEEIK
RSFREQLYCLLFENVDGLLLETYYDLDELITVLKIARQVTNIPIITNVSMHEPGVLENGI
LLSEAIKRLEDLGADVVGVNCRLGPYHVLKALETVPIPEKAFLSAYPNSSLPEFRNGKLL
YKSEPEYFKKFAAHFRDEGVRLMGGCCGTTPDHIRSMKEGIQGLKPIKKKKVKEQARIEI
AETKKLDELTLFEKVKTKRSIIVELDTPKDLDTRRFFEGAKALKEAGIDGLTVADNSLAS
PRICNKTMASLVKRDIGLSSLVHVTCRDRNLIGLQSHLMGLHTLGIRDILAITGDPTKIG
DFPGATSVFDVTSFDLIKLIKQCNEGVSFSGKSLKQKTNFHVATAFNPNVHNIKKSTERL
EKKIQFGADYVLTQPIFSREKIIETREATKHIKAPIYIGIMPLVSSKNAEFLHNEVPGIK
LTDETRKRIAIAKSPEQELRTGLDIAKELIDTAIEYFNGIYLITPFIRYELSVELAKYIQ
QRTKELDAKKQSQFVLS
>A0A2N6CB92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKSASNLERVLTAGEFAVTGELGPPKSGNPEVVRKKARLVKDCCDAVNITDCQTAVVRMS
SIAAGLITQSEGVEPVIQMTCRDRNRISMQSDILGANALGLKNLLCLTGDHQKFGNHPGA
KGVFDMDSIQLLSMMRDMRDGKKFQCGEQIKEHEPKMFFGCAANPFAEPFDYRAPRLGKK
VNAGADFVQTQLIYNVERFRKFMEMCDDLGISEKTYILAGITPPRSLGMARYMKKFVPGL
EVTDDIIQRMKDAKDKEDEGINIAVDIINEVREIKGVAGVHIMAIEWESALQEITSRANL
LPRPVIAGEPSEAVISFQAEAAAPGEKPGDIIAAAKAEAEQIIINAKQEAASLQTPAAEP
VQVSTETEVPAVTAEDLGEDEMNEKERQMALESVRGGLEALKKAFGLSDEQFEALEKFSG
AESILKRDPGVKAATPSAAPAAPPPPAAPPAPAAPAPPAEATTKVEDDKAVEAAKAEEAK
AAEAKKAEEAKAAEAKKAEEAKAAEAKKAEEAKAAEAKKAEEAKAAEAKKAEEAKAVEAK
KAEETKASEEAKKAEKPKAAAAPAGVGAAELAAEETALSDRASKLPEDHYKIAYSGTIRE
ITLGNADKTETVGGATSLPFQLFEGDMPRKPLIAMDVLDVAPEEWPDSLARHFEGVLDNP
VAWAQKCVNDYGAGAICLSMVSTDPNGMNRPSAEAAKVAADVINSIDVPIIIWGCDNAEK
DTETLRDITAMIGDKKVCLAPLTDANYRSIGATAMAFQHPVVAASPIDVNLAKQLNILME
NLGMHLDTVLIDPSIGALGYGIEYSYSVMERIRLAALTQQDDKLQVPFICNLGREVWKAK
EAKLPSDDLIGDQENRGVLMEAVTASMMLMAGGEVMIMRHPKSIALIKSLINGLTG
>A0A1Y3WQR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. An58|TrEMBL
MKNAREILKDRVLLFDGGMGTYYKARPGLECEQANLEDPAGILAVHREYLAAGAQALKTN
TFGLPRMAAAHVPGWQQLARAGWELGAQALAEAGGEGALFADMGPAPDTEADPAAQSYKA
VAEVFLELGAENFLFETLSSDAGLAEAAAYIKSRRPDAFVLVSFAALPDGYTREGLSCRE
MAARMAACGQVDAVGLNCLLPPGAMAPVLQGVAGCGLPVSAMPNGGYPLVTRSRVVYRGR
PDYFAREMCRIRAGGAVILGGCCGTAPAHIAALRQALEETPIPICGTEAPAPQPEAQILP
AVSDPFLRKLAQGERVIAVELDSPRDADLTGYMASARRLQQAGVDALTIADCPIARARVD
ASLTACKLRRELGLVAMPHMTCRDRNLNAIKALLLGLYAEGVREVLAITGDPIPTAERDE
VKSVYQFNSRKLARYIHALAGPGEALPGMTVFGALNLNARNFDVELRRAQEKQDSGMAGF
LTQPVLSARAVDNLRAARAALPGAKLLAGIMPVVSHRNALYMENEINGIHVEDSIIRRYE
GADRARGEELGLEISLEMARAAGPWADGFYLMTPLGRVGLMEQLVQAIRREGL
>A0A2N6CBW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MNFASELSRNTSFPICYNLLPHFTAKGQEYTALTKCVTEAVNDGRIHTFLLADFLIHRQG
FSSLQLAEKILASGGEPVVSLSLTFNDRDTIIDKLQGYYRAGVRHFLIVSGDYPSQAPNK
PTRPVSEIDSVQLLMLLDDFQKKGDIAKGCVVSPFKTFESEQVWQYEKLRRKIRVGADFI
ITQLGYDIRKFDELIRFCALHEIAAPLVANIRITDMQTARLVQARSIPGVKIPSPLLHTL
HEEASNRQGALGRAAKVLAVLKGLGYDGALIGNHSTDFSEVKQVLDKAEALQNDWQNFLD
ELNFSDAESSFYYFRKDPQSGLNRGETASVALKHFPSPTYSFSYFVDWLVYVPRGPLFKL
TGRFCHFCSTRKFWYTFLWLLEYVSKGVLYGCKMCGDCTLYACGFLCYQSGCPKKMLNGP
CGGSSEGYCEVFPEKKRCYWVKVYHHMKGVNQHVTFVAPPIPARDTSLHRTSSWINFFLG
KDHRKMNFDDS
>A0A6S6M496|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrifermentans bremense|TrEMBL
MKIVEKMNQAQQFVSLEFFPPKDKNEWPAFFKTVDRLSQINPLFASVTYGAGGSTKGDTL
EIVKTLQSGNGLDTMAHLTCVGAYRGDLQRFLDDLALAGVKNVLALRGDLPSDEPPEFSA
CRTLLHASDLAAFIRESHPEMGVGVAGYPETHPEATDTECDLGYLKLKLDQGGDFVITQL
FFDNRLYFDFVAKARAAGIDKPIIPGIIPVVSLKVIQRIISMCGATLPPAYLAELEAADR
SGGAAAVQKVGIAYARRQAQELLGAGVPGVHIYTLNRDQAVLELVDGLLPS
>A0A2S7ZD87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. T14073-2|TrEMBL
MTLREKHQQGKFTITVELDPPKSSSAQKVFDQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKDIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNGA
HFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINITQEILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A0C3PPI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pisolithus tinctorius Marx 270|TrEMBL
MKVSKKIEQSQKEGKIWWSFEYFPPRTAQGLQNLLDRIERMRNLGPEFIDITWNAGGRTS
ELTSEMVRLCQGVIGIETCMHLTCTNMPREKVDVALCEAKKHGCRNILALRGDPPQGKDE
WEAVEGGFVHGIDLVRHIHKEYGDYFDIAVAGFPQNMLLPPEERDLEIKYLKEKIDAGVD
FIFTQMFYDVDIFIDWVKAIRAAGITIPIVPGVAPIQTWNGFLKATSLAQTKIPQSFMDA
LEPHKNDDEKVRAIGTKLVADMCRKILDADLGIKGLHFYTMNLEKGTKMLLQELNLVPRV
ETLKPLPWRQSLTPNRRQENIRPIFWANRTQSYLSRTENWDEFPNGRFGDSRSPAYGELD
GYGVSLKQTVWKSLKLWGEPKTFDDIAQLFSQFCLKKLSALPWSDQPVSGETSIISKELS
KINLLGFLTINSQPAVNGAPSDDPKFGWGPRDGYVYQKAYLEFFVNPELLEILISEIEMD
TKMTYYVINKQGDLRTNSHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYDLGVK
WANIYETASPSRQLIMDVMDNSYLVNVVHNDFKDTKAIFAPFFKAGEKYAASRATANGSA
QTNGDLN
>A0A2N5B397|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium loti|TrEMBL
MTPPRPPQRDENPAGIHLPLERLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKVFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPVMQIACRDKNRIAIQGDVLG
GAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQ
VFLGAAINPFAPPYDFRPIHLGKKIAAGAQFVQSQYCFDVPMFKTFMQKASDLGLTEKVF
VLVGVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAEDQKAEGKKLCIDIINEVKEIPG
VSGVHVMAYRQEEYVAEIVDESGVLKGRQPWKRETRPDDARVAERLGHILHDDITETQVD
MVKTAH
>A0A511RI99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanithermus desulfurans NBRC 100063|TrEMBL
MRLTDKLGHGFVLTAEVDPPRGADPAPTLKQALILRGYVDAVNVSDAPMANLRMNSIMLA
HLIQHHTGVEVIPHLTARDRNRLALQADLLGAWALGVKNVLVLGGDPPERGDHPEARPVY
EFGAVGLVETIARLNRGENLSGGSLEGAPDLTPGVAVNPGAADLAAEAEKFWAKVEAGAR
FAQSQPVFCPETAATFLDALGGRSPVPILWGVLPLRSLKMARNVGRWTRVPEALVADLER
EGRAAGMRAAQHVLRELHAAGMDGAHLYPLGRVELLKEMLKPLGARLG
>A0A143YJB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus palustris|TrEMBL
MKIRDMLAKGNPTVSFEIFPPKSTYPLETVFETMDSLKDLNPDFISVTYGAGGSTKGNTV
DIASRIKKDFGIEAIAHLTCCTSSKEGIQETLASIKESGLENILALRGDIPEALQNDKNW
NPQYRYASELIDEIKAFGDFSIGAACYPEGHVESKNMVDDLKNLKRKVDHGADFLITQLF
YDNELFYQFREKMELVGVDKPVIAGILPVLNIKQVKHIQKISGCNLPPKFLRILDRYEHD
PQSLQEAGIAYAVDQIIDLLSYGVDGVHIYTMNKPDPTRRIMESICSVRQAACKAVK
>A0A3A6MVE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ammonifex sp|TrEMBL
MAVSKFKEALNSGKFLVTCEIGPPKGTDLTQMLHHVDLLKYRVDALNVTDHQSSVMRFPS
LGGCLSVKEKGGEPVLQMTCRDRNRLALQADLMLAHTRGINNVLCLTGDSVIVGDHKGAK
GVFDLDSVQLLRAVRQMEAGKDMAGNDLEGGVSFCAGAVVTPEATPIEPQLIKFEKKVEA
GAEFFQTQAIYDLERFAKFMEYARQFPVKILAGIVLLTSVGMAKFINANIPGIVVPQDLI
DELANAGRGRALHKGIEIAGRMIAALKKDAICDGVHIMAIGKEEVVPEILAKAGL
>A0A353NC59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKLMTMRRPFHDRSLVRLPCHRRARSPLSLKKAIHFTHLTGGSMDAAQEISSPAQKKFSL
IAEMDPPKGVNLQGFVDTALQVRGRVDAVRVTDCEHAIMRMSPIAPCLALQDKGYEPEMI
ITGRDRNRISFQADLLSAAALGIKKIVIKEGHDPAEGDQPVARTSGDLDLESMLQCVAAL
NSGRDLAGESLDGATDFQVGVAIELSDDVNLNRERAEYFKKLAVYGVQSVTLGPSYDINI
IEQFLPFAEETKIKLYTSVMFLKSVTMIRYLNNLPGVPSIPNEFLKKMMQAPVKKDAGMQ
VAADLCKELAPMGDGIVLLAIGLKDKLPEFLDIIGR
>A0A4P5VHN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp|TrEMBL
MLLQDALQAGQFALTAEVTPPRGGDPSRAVEVASLLRGRVHAVNVTDGSRAVMRMSSLAL
CRLLLEAGIEPVLQMTCRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAGDQPAARPVN
ELEAVRLLQLVGRCNAGLDPVEGTLPDGPTLLFPGAAADPQSPSWSGLASRVRRKQAAGA
RFLQTQMVMDEAALRRFVEEITAPLGLPVLAGVFLLKSARNARFINRVVPGACIPEVVIT
RLEAAKDPAAEGVAIAAEQVQAYRTIAQGVHLMAVKAEERIPCILDLAGI
>A0A3N5EQU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MELKTSSRLEKVLKSGQLAVTSECGPPRSSNPEGIIKKGQLIKDHVDAINVTDNQTSVTR
LCSLAACVHLKLQGLDPVLQMVVRDRNRIALQSDILGAASFGINNVLCLSGDHQSFGDNP
QAQNVFDLDSMQLVQTVRQMRDEGKFLSGDEIKVPPNLFVGAAANPFADPFKIRVPRLAK
KIAAGAEFIQTQCIYNVDKFELWMQGVRDRGLDEKIYILAGITPMRSVGMAKYLKKSVPG
MDVPEELIKRMSGVEKTQQAAEGITIAVETIQRLKEVKGVSGFHVMAIEWEEKVPEIVER
SGLFPRPTIA
>U1HHX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endocarpon pusillum (strain Z07020 / HMAS-L-300199)|TrEMBL
MEKITDKLAALPPNTNYFSLEFFPPKTQAGSSNLQARLIRMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCMHLTCTNMSRALVDEALEEAKALGIRNILALRGDPPRSEE
YHMDGQENSNKDFTWAVDLVRYIRKVHSDYFCIGVAGYPEGHADDSHPEHQSVERDLPYL
VEKVKAGGDFIMTQLTYDIEAYTRYEDTLRSHPSGIFTSIPLIPGLMPIQSYQIVKRITN
LSHARIPAEMFSRIEAVKSDDEAVKRVGVDILSELVEGIKALPQPKSLPRGFHFYTLNLE
KSVAFILERCKLIPSSTEPTTPSTSDSESEIAITTMTNGPTMVINGTGELSKRSFSRRRA
SSFNSQPHNRLIVDNVSARDVGSRHRLPSGAQSSQGSETHQTPSECAGIPAGPSTRSNTL
LISEGQGSLGREATWDDYPNGRWGPSSSPAFGEIDGYGPSLKVGPVAARRLWGHPKSPED
ITGLFRKHVEGELVCVPWSDETDVTSGGALRAETEIIRPELIALIEGKGFWTLASQPAVN
GIKSDDEVFGWGPPGEGFIFQKAFVEFFVSRQSWEKEVRPLLQMHGEDELSWLKTDKEGV
FESSASAEMLVDPTTSKPAAGATGVNAVTWGVFRGKEIVTPTIIEEQSFRAWGEEAYGIW
EEWRRLFPRGSEEEKFLESCKRDYVLVNVVGQRFVGKDGARLWEILALR
>R6RHJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerostipes sp. CAG:276|TrEMBL
MKISELLKEKATISFEVFPPKNKEGDISSIYYTIEELAKLDPDFISVTYGAGGSSKGKTV
EIASAIKNKYQIESVAHLSCITSTKEDILTECRALKEHNVDNILSLRGDYPAGEEEKYRG
MDLEFHYASELNGFIRENFGDSFCLSGACYPEVHQEADCFRDDLEALKKKVDAGAEYLIT
QIFFDNSYYYRLVKEARKIGIDVPILAGIMPVTNAKSLLRTAKLCGCSIPFQLSTMIETY
YNYPEAMKEIGINYAAHQIIDLITNGVDGIHIYTMNKPEIAQRIFGNIPTVLKELNHD
>A0A1E3K1T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus wingfieldii CBS 7118|TrEMBL
MKITDKLQKAEKEGRPFWSFEYFPPRTAQGLQNLFDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVEICQSTIGIETCMHLCCTEMPKEKVEWALKQAKQNGCQNILALRGDPVAGTST
WEPTPGGFMNAIDLVKYIHQNYPGDFCVAVAGFPQGHPESPLTPEGKEQEMKWLKEKVDA
GSDFIFTQMFYDTDIFFDWVKRVRAAGITVPIIPGIMPIQNWEKFDKWVQRENIIVPQHF
YDALNPVKGDDEKVRQVGTKLVAEMCRKILENKEAGIKGLHVYTLNLEKGARMLLQELGF
EGRREQIAPLPWRPSLTPSRRDETIRPIFWANRTRSYISRTEDWDEFPNGRWGDSRSPAY
GDLDGYPVSIGISTTEAYNLWGNPTTTAEIYNLFARFCRGELTKLPWSTQPPASETSVIT
DQLSKMNELGYLTINSQPAVDGVASDDKVHGWGPSGGYVYQKAYLEFFVSPELLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIIQPTIVEAVSFVAWKDEAFE
LGLQWANLYPAGSPSRELVTKVMNNSYLVNIVANDFRDGLSIFEPFLLDQTPVGKVVEGV
KDVVEGVVEGVKSVVAE
>A0A424SJT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium TMED144|TrEMBL
MKVIEFLEKANKTLFSYEIIPPLRGGSIEKIFNLVEKLKPFDPPFIDLTSRSAEVFFEEN
NGNRFKKHIRKKRPGTIGISAAIKNKFNIETVPHILCHGFTKEETEDALIELNYLGIDNI
LAVRGDDLRFDKRASENPNVNQYASDLVAQISNMNKGIYLENLIDSSLSNFCIGVGGYPE
KHFESSSLDTDITNLKKKVDQGADYIVTQMFFDNKVFFNFVEKCKQAGIKVPIIPGIKIL
SSEIHLTKLPKYFFLDIPNELSNQVIGRDRNEIREVGVKWAQNQVHELIEFGVPCVHFYI
MSSAKSVVEVISEF
>A0A6P0S9G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO2I5|TrEMBL
IPDEIIDRLAAADNQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPL
QKSSAVNDLVFR
>A0A654M6A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus infantarius|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYETYNLTHPEKVLAIHKTYIEAGADVIQT
NTYTAKRHRLDGYGYGEKIKEINQAGVKIARQAAGEDTFVLGTVGALRGLKQCELTLNEI
IKETLEQVRYLLETEEIDGLLFETYYDEEEIIEVLKVVRPLTDLPIITNISIHEAGITEN
GRPLVEIFGKLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVSRKFVTP
MVEEAELIKAVKQSETIVDKVKRKVTIIAELDPPKTLDIRKFTKGVKALDEAGVAAITLA
DNSLAKTRICNVSIASLLKNEISMPFLLHLSCRDHNMIGLQSRLLGMDVLGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIKQLNKGIGYSGASIKKETTFTAAAAFNPNVKNLS
RCGRLIERKIAAGADCFITQPIFNSEIIENLAELTRDYDTPFFVGIMPITSYNNAIFLHN
EVPGIQLSDDFLAKLEAVKDDKEKCQQLALEESKQLIDHALKFFNGIYLITPFMRYDLTV
DLVEYIHQKVEQSHQIIP
>A0A268SBV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. 7516|TrEMBL
MKADLRSVLQERVLIGDGAMGTYLYQMGFPVGISYEELNLVSPEVVADVHRRYLEAGTEI
FETNTYSANYDKLSKFGLESKVTEVNRAGARIAKEVAGSNGYVLGAVGSIRGGKRTNVST
SELKRFYEQQIFALLEEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDIGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGVPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFADLGARIIGGCCGTTPDHIAAIAQALSEYTTAPIVLPDPTE
AKPRIVLHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLDKAVQRLEKKIASGADYIMTQPVYDPQLIVAMHEATKHLEVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A7W4ITT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconacetobacter aggeris|TrEMBL
MSLPQPPGPGLSFEFFPPKTPKMAEALRQTASVLAPLGPRFISVTYGAGGSTRDRTLQTV
AELVRETGVPVAGHLTCVDATRAEVDAVARAYWDAGVRHIVALRGDPSEPGAPFVAHPDG
YAGAVELVAGLRRIAPFEISVAAYPETHPAAISPAADLDHLKAKIDAGATRALTQFFFEA
ETFLRFRDRATAAGITTEIVPGILPVANIAQAYRFAEMCGAHVPDWMRRLFDGLDDHPGA
RAMVTTAVTAELCRQLRDHGVTDLHVYTLNRPDAALALHRLLHSGGTP
>A0A3R6XYH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. OM04-11BH|TrEMBL
MLDVRKLLTRRPLLFDGGMGTYYKTKPGQECEQANLTDPEGILAVHRAYLAAGADAIKTN
TFSLPRLAAAQQPGWEQLADAGWQLAAKAAGETGAAVFADLGPAPDTENFPAEQVYLAVA
KRFALLGARNFLFETLSTEDGVLEAIRALKRTVPEAFVLVSFAVLPDGYTREGRYCAELV
RRMAQSGVVDAVGLNCVSAPGAMRALVQQLGDAGLPLSVMPNAGYPVVARAQVRYQGKPE
YFARELSRLAAEGVRILGGCCGTTPQHIAALRTALDALPETLPAAPAAKPAEAAKSVVEM
DDAFLRKLRAGQRVIAVELDSPKDADLTAYLEGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGMNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPITVFGALNLNARNFEVELRRAAEKLENGMSGFL
TQPVLSAQAVENLKKARETLGEQAKILAGILPVVSQRNAIFMENEVNGIHVDEAIIQKFE
GLDRAAGEELGLEVSVQAAKAAAPYADGFYLMTPFNRVALMERLIARLRTEVTD
>A0A8B5YUB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas vasicola|TrEMBL
MMSTDTPSLANTIADAYSLEVSVKDIGALTKAAPRMLPGSTMFIPYLPGQNDAARLAAAQ
MVRGLGFEPMPHLSARRMTSLDELQAFVARLVDEAGVTRCFVIAGDPSTPKGPFADSLSL
IDTGVFERAGIRTIGVAGHPEGHPIMHTAEQWDVLERKCRSIEERGMAAVIVTQFGFDAD
MVVTWVEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSKYGISIGKLFGN
AGPDRFVDRLVSCLTEAHGDIRLHVFPFGGIAQSVEWVAHYRSRNAPQDRISAVRADRP
>R6CAG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:510|TrEMBL
MKISDILREDKTTISFEVFPPKTTANFESVKKAALGVAALHPDYMSVTYGAGGSDRGNTL
HIAEEIQKAENVTTIAHLTCVGAGKEDIRTALSEMKEAGIENILALRGDRPKDFDGDPFK
EYHYASELVATIKEYGDFCVGGACYPEGHPDSTNKKEDIKNLKKRWTQVVSSCPSF
>C4KXI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei MSHR346|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A5B7TUB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium 10Alg115|TrEMBL
MKITEHIAQAKGKTLFSFEIIPPQKGKNIQELYNNIDPLMEFKPPFIDVTTSREEYIYID
KDGLLDRKTTRMRPGTVGICAAIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIENV
MALRGDAMKHEQYFKATNGGHTFATELVSQIQNLNAGKYLHDVIDADDKADFCIGVAGYP
EKHLEAPSLVTDLKRLKQKVDAGADYVVTQMFFDNKKYFEFVAAARKEGIMVPIIPGIKP
IAVKRHLQLLPQVFKIDLPEELIKEVDKCKDNKAVRQVGVEYCIQQSKELLKAGVPVLHY
YSMGKSDNVKAVAQGVF
>A0A0L0BHC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. RIT-PI-e|TrEMBL
MAELPVSIEVVPAGGLVARLRDRLPGSAVLAVTCLPQHGPARTVDTAVGLVGAGSPAVPH
RAARSGASRRELAEYVSRFRDAGITGVFVVGGEAGEQAGPYAWSGGLLEDLAELGGGSLR
LGVAAYPEGHPDTAPDVLAEDLRSKQELASWCVTQLCFSPEILAGFPARLRADGVTLPVW
AGVPGPVHMTKLLTLAGRIGVGSSLGFLRRSAGGARTGSAVRQLLSSAAYDPSPLVRAIE
GAGYAGLHVYSFNDLAGLAGSGLVGGSR
>N1NQA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus nematophila F1|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPSTTEMEQTLWKSIDRLSRLKPKFVSVTY
GANSGERNRTHSIIKGIKEKTGLDAAPHLTCIDASREELRDIAHDYWQSGIRHIVALRGD
LPNNCCKPEMYGADLVELLKEEADFDISVAAYPEVHPEAKSAQSDLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFSTMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPV
>A0A5P6VQW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio xylanivorans|TrEMBL
MFKDMFKRDSSLSFEVFPPKKDDEFENCYKVLDSLATLEPDFISVTYGAGGSRSKKTVDI
ANYIQNTLKLDAMAHMTCVGSTQDDILAVTKDLEAVGVSHVLALRGDKPRDMSDEQFEQR
IFPHATDLIHFLNQNTSLKVSASCYPEKHPEAISMDSDIAFMKMKQDMGAEMFISQLFFD
NADFYRFVERADKAGITVPIVAGIMPITSAKQIGSTVTLAGSSVSKKLADICARYGEDAD
AMRSAGIEYAISQINDLRKCGMGHIHIYCMNKPKMTAEICDAIK
>A0A2G5I685|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HG99|TrEMBL
MAVHTSPGTAGDPASGAAVRSLIGDAAIEVIPLRSADEKLKAIPEGTTVSVTTSAKLGLG
RTLEFAERAVRAGFNVVPHLAARQLTGEEELRRFIGRLGELGISRLYLIGGDVTPPAGPY
DSSLQVLEAMQRMDHGLRRIGVACYPEGHPKISDAALSEALRDKQPYAAYMVSQLCFSPE
VLVSWLRRVRGEGITLPLLIGLAAPMQVTKLIKLGPQIGVGTSVRYLAKQHGFIGNVLKG
GAYRPESLLLEIGDAVTSPELGIEGLHLFSFNQVEETVRWQRDITAASSGAAR
>A0A430FNW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium samirii|TrEMBL
MHTPIFSLEVFPPKRDAPIGTIYDTLDGLEGLKPDFISVTYGHGTHADRTATARIANTIR
KDYRIPTVAHLTALYADKAKIDEALDLFEDAQVGGVLALRGDHLPGCESEETGVFPHAAD
LIAYIRERKPDMKVFAACYPEGHVESGSLDEDVAHLKEKVDAGATHLMSQLFYDNADFYR
FLDKTRAAGIDVPIEAGIMPVTSAKSVRAMAARNGTRVPKAVATMLDKWGDDLPSLRAAG
IGFASQQIGNLLANDVQGIHLYTMNRPATARRIWRNVEPLFTR
>A0A849QWB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon|TrEMBL
MGFADVLGSGKFVVTAEVSPPRGTDISGTLAGARLLQGLVDAVNVTDNQRSMMRMSPIVL
CHKLGEMGFETIMHMTCRDRNRLALQSDLLAAHALGIH
>A0A8G2ZBT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPPQARSFEDDLANFVRKVKAGASSAITQ
YFFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYG
DDSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A7C1BYQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSFRDIVESGKFVVTGEIGPPKGTDIKEVLHHIELLKGKIDVANVTDNQAAVMRISSLAG
CQLCLQNGLEPVLQMTCRDRNRIGLQADLLGASVLGIKTVLCLTGDHVNAGDHKQAKSVY
DVESVQLLKIVNGMNNGFDMSGNELQGATDFYPGAVVTPESVPLEPQLVKFEKKVEAGAK
FFQTQAIYNMDKFKDFMKYARQFPVKILAGIVVLKSAGMANFMNKNVPGIMVPQDLIDEM
KAAGKEKALDTGLNIAARHIRQLKEEKICDGVHIMAIGMEDKVPEIMERAGLL
>A0A318XRM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminiclostridium sufflavum DSM 19573|TrEMBL
MSIFEGKEYFLFDGAIGTYYSSKFNKNTACELANLFDRDSIYDIHREYISAGANAIKSNT
FGANRFSLACDQSEADKIIIKGWEIAKRAAEGTAAAVFADIGPLPMDENISAPEEYKKIV
DIFISCGAENFLFETFSGYDILLELSAYIRLRIPKAVIIASFAVYPDGYTKEGLFYKDII
DKVSTSGLADACGLNCISGPAHMCRLVKDLNIQGRRIIIMPNSGYPSSERGRDLFIDNSD
YFAEKILDLKKMGVQILGGCCGTTPKHIAALAGLLDANNHQEGNLAHKVNSTACVPSEEN
VLYKLLESKKPILVEIDPPFDTKWEYMLKDAFLLKQAGADMITIADSPLAKARADSSILA
SKIYREAGIPVMPHITCRDKNLLGIKAMLLGLHIEGIRNILTITGDPIAHTERENIKGVF
SINSSKLAGYISSLNSNVFHDGEFKIGGALNVNAVNFDAELRRSVNKIENGIGYFLTQAV
YTDAGINNAVRAVQTLKVPVFAGIMPLVGYKNAQFINNEVPGIEIDEETIELFRDKSREE
SERIGINFSMKSINKLYKHVSGFYLMTPLKRTHVICELIKMIREINI
>A0A8H3M6Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus clarus|TrEMBL
MKVINKILKAHEEGRPSWSFEYFPPKTQQGVQNLYDRMERMYRLGPEFIDVTWNAGGTSS
QLTSEIVATAQSVYGLETVMHLTCTNMPKEKIDKALKDAKECGCQNILALRGDPPRGQEH
WEACENGFSHAIDLVRYIRQQYGDYFGIAVAGYCEGHVDNPDKNDDLYRLKEKVDAGADF
IITQVFYDVDIFLNWVKKCRAIGISCPIIPGILPIQNYSGFNRIITLSKTIVPQFVLEEL
EPIKDDDAAVKEYGIRLAVDMIRKMFADGIKCYHFYTMNLERSTRLILETLEFVPPIENV
KPLPWCPSLSAKRKKENVRPIFWRNRTKSYIARTEAWDEFPNGRWGDSRSPAFGELDGYG
VSLKHSKKEALALWGYPQKLDDIFDVFVQYCRGEVNSLPWSDQPLARESNIIKEQLAHIN
SLGYLTINSQPAVNGVRSDHKIFGWGPKNGYVYQKAYLEIFISPAQLDTLIARIDRDSNI
TYYAVNKQGDLKTNTQSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELWNEWAK
IYDAESTSTKLITDIADNWYLINIVHNDFHDSDGEYV
>A0A6J4LXM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Gemmatimonadaceae bacterium|TrEMBL
VGGDRSAARGGRLEAAGRRGDAARRRGGRDQRARRAARAEPDGGDHDVAAHRAAGGDRDG
DPLRLPRPQPAGDVERPPRRLGGGAAQHPAHHRRPAEDGPLPGRHGGVRHRRDRAHEPGA
QPEPRHGPRRQLDRRADALRDRRGGEPGGARPRARAATLRVQGRSGGRVRDHAAGVRRRA
ARAVPGHGGAHAHPDGRRRVAAGLGAQRGVPRQRGAGRHGAGRDDRADAARERALQGARR
RRGDRDRARAAGAGARERAGGAGERPIRPGGAGAAGVRGPHRRAV
>A0A2W6E5T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MTAVIDRLGGDRPVFSIEFSPPRDDAGERQLWQAVRDFEPLDPAFASVTYGAGGSNRDRT
LRITKRIVQETTVVAMAHLTAVNHSVAELRQVIGNYAQAGIRNVLALRGDPPGDPLGEWV
AHPQGVHYAADLVRLARSLDDFCVGVAAFPERHPRSLDAESDVRYLVAKLRAGAQFAITQ
MFFRPEDYLRLRDRVAAAGADMATVPILAGVMPITTLRGVQKMAELSGCTIPAAVRDRLV
AVGDDAAAVRQVGVDVASELCERLLAEGVPGLHFYTLNRSGSTRAVLARLEMAPTVATR
>A0A2W6D9E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MRRALASGRFVVTAEIGPPRGADPAAIARKADLLRGWVDAANVTDNQSAHVRLSSFAGSL
LVLSAGVEPVMQLTCRDRNRIALQSDLISAAALGIPNILLLTGDHPRFGDHPEAKAVFDI
DGVQLVWTAATMRDQGRLLSGRRVDPAPHWLIGTVENPFSPPISFRARRLAKKVAAGAEF
VQTQFVFDLPIFERFMAEVRDLGIHHRCGVIAGVGPVRSLRALEYIATKVPGIHVPDAMI
RRLRGVPADRVADEGMQICVEIIERLTEISGVAGAHVMAFGHERGIPEILERAGVGPRPD
HAAAHEGSGRAG
>E6BQ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli MS 85-1|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1G3JBB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriia bacterium RIFOXYD2_FULL_35_12|TrEMBL
MKVTEHIQQAKNTLISFEVLPPLKGKTIQHVFDHLNPLMEFKPSWINVTYHRSETAFKKK
ADGTFEKVEVRKRPGTVGICAAIMNHYSIDTVPHFICGGFNKRESEDALIDLNFLGIDNV
LVLRGDAAKNEASFEPETDGHKYAIDLQKQVVNLNSGIYLDEDIQNGGKTNFCIGTAGYP
EKHFEAPNLEIDLQRLKEKVDAGADYIMTQMFFDNQKFYDYVKACRDMGITVPIIPGLKP
ITNKKQLSVLPRIFHVDIPTDLSNAISKCKTDADCEQVGTEWLIQQSKELKAFGVPVLHY
YTLGKPKVIWNVVNAVC
>F4HAL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallibacterium anatis (strain UMN179)|TrEMBL
MSYAKEIDVLNRSIADLNGDINVSFEFFPPKNEKMETLLWDSIQRLKSLQPKFVSVTYGA
NSGERERTHSVVKAIKQQTGIEAAPHLTGIDASPEQLKAIAKDYWDSGIRNIVALRGDEP
PGYDKKPFYAKDLVKLLKEVADFDISVAAYPEVHPEAKSAQADLIFLKQKVEAGASRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFVQLQKMAKVTNVKIPSWMFKLYDGL
EKDQTTRNLIGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGVRPSLAA
>A0A1V5CCM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdaceae bacterium PtaU1.Bin034|TrEMBL
MSASNLERVLKGGNFAVTSECGPPRGSNADVVRKKGAFLKDAVDGVNVTDNQTSVVRMSS
IASSIILKEMGFDPIMQMVCRDRNRIAIQSDILGAAALGLNNILCLSGDHQTFGDHPTAK
NVYDIDSMQLIQCVAGMRDEGKLLGGQELKGKPDMFIGCAENPFADPFEIRAMRLAKKAA
AGAQFVQTQCIFNVPKFEKWMEMVRDLGVHEKIYILAGITPFKSIGAARYMKNNVPGMDV
PDEMIGRLKGVPKEQVQEEGIKIAIETIERVRRIKGVAGVHIMAIEWEEKVPEIVKAAGL
YPRPQAVP
>A0A4Q1AWT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halarcobacter mediterraneus|TrEMBL
MLTDKIRNKEGGILLYGITPPKIKHTKEEIKEIANKHIDRISKLNVDGLVLYDIQDESDR
TDEKRPFPFIKTLNPCEYSRNYLQELKTPRIVYRAVGNYTAKQFTAWLEQTRETQVHSVF
VGAASHEQQTNITLKEAYSLKREVNDNLCLGGIAIPERHSKKHDEHLRVASKINESCEFF
ITQCVYDLEASKIFLTDYAKYVKENSIDAVPIIFTLTPCGSSKTLDFMKWLGINIPNYLE
EELKESKDILAESVKLSKEIFEELFIFGKKRDIPVGCNIESVAIRKAEIDASVELLEEVK
KIIKKHS
>A0A2Z6S7K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus clarus|TrEMBL
MKVINKILKAHEEGRPSWSFEYFPPKTQQGVQNLYDRMERMYRLGPEFIDVTWNAGGTSS
QLTSEIVATAQSVYGLETVMHLTCTNMPKEKIDKALKDAKECGCQNILALRGDPPRGQEH
WEACENGFSHAIDLVRYIRQQYGDYFGIAVAGYCEGHVDNPDKNDDLYRLKEKVDAGADF
IITQVFYDVDIFLNWVKKCRAIGISCPIIPGILPIQNYSGFNRIITLSKTIVPQFVLEEL
EPIKDDDAAVKEYGIRLAVDMIRKMFADGIKCYHFYTMNLERSTRLILETLEFVPPIENV
KPLPWCPSLSAKRKKENVRPIFWRNRTKSYIARTEAWDEFPNGRWGDSRSPAFGELDGYG
VSLKHSKKEALALWGYPQKLDDIFDVFVQYCRGEVNSLPWSDQPLARESNIIKEQLAHIN
SLGYLTINSQPAVNGVRSDHKIFGWGPKNGYVYQKAYLEIFISPAQLDTLIARIDRDSNI
TYYAVNKQGDLKTNTQSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELWNEWAK
IYDAESTSTKLITDIADNWYLINIVHNDFHDSDGIFKIFEQISVTDYEADR
>A0A5C4Y5K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus radiopugnans ATCC 19172|TrEMBL
MTRVSIELVPRSRSGLRAELAAVAEHLPGADTINIPDFPRFSTRSWHGCAFARPHHRAIP
HIRAVDLNPREPLPMAAHLDQHGIDEVIVITGDAPGDMNARVYNVDAEAAIRRIRRELPH
LKVYAGLDPYRQSLSREQSYLERKLEAGACGFFTQPFFDLRLMDAYADLLPEGVEVWWGA
TSVTSEGSEGYWRTRNHAVFPRRFEATLEWNRRFACELLTFARERGQHAYFMPIKADVVE
YLGGIV
>A0A521LA77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reyranella sp|TrEMBL
MSPDTGPLSTGTSTGASEFPARAPQRLKVSFEFSPPKTEAAERTLWETVNRLTPLHPTFF
SVTYGAGGSTRQRTHETVARLKKDTGIDAAAHLTCVAATQGEIDDVARAYWDAGIRHIVA
LRGDPPGGMGGKYSVHPGGYENAAALVKGLKKIGDFQISVAGYPETHPDSADAKADLENL
KRKVDAGADRCITQFFFDPDDFLRFRDNAAASGVRVPVVPGIMPVSNFQGISKMAALCGS
KVPAWLKELFQGLEDDVETRRMIAATVAGDLCRRLHAEGVDQFHFYTLNRADLTFAICHL
LGVRPR
>A0A6W0NZM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Rubislaw str. ATCC 10717|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8H4PSH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps sinensis|TrEMBL
MTQLFFDIDAYERFEKTLREHPSGAFTSIPIMPGLMPIQGYQMIKRTTKLSHARMPESIM
ARLNAVRGDDERVKMVGVDVISEMVEQIRAIKTGDSGHRGFHFYTLNLEKAVSLIVEKTG
LMQQDSSDSDEAVVDDVPLSPLPIIQLNGNAPLRPSSHSRTSRRHSSVGSDPHNRVIVGN
RPLAHPEWEAAGQEAGVPAGGINSRANTLAISEGEGALGREATWDDFPNGRFGDARSPAY
GEIDGYGVSLHMSVTQAVRLWGYPATRRDLDDIFVKHMQGQLAAIPWSEEELMAESSTIK
PCLIELNSKSWWTVASQPAINGAPSSDPTFGWGPVNGFVFQKSFVEFFLPSDDWKALHER
LSSPEVRESICFYATNSVGDFASSDSSGGLNSASSWTSTNAVTWGVFPGKEIVTPTIIEE
VSFRAWSEEAFGIWGEWAKVYGRGSDSETLLNGIRDDVWLVNIIHHDFVDTNALWKLLLE
>A0A6P4Z240|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Branchiostoma belcheri|TrEMBL
MSSSGYTSSGASTPSNGSRPSSPGPGVPYVKLADRIEAKINRGERWFSLEFFPPRTPQGA
ANLISRFERMVQGGPMFMDITWHPAGDPGNSDKETSSMSIACAALNYVGHETMLHMSCCN
STKDDIRRHLDKAKELGIRNILALRGDPIVGDEWKYVEDGFNYATDMVRFLRAEFGDYFT
VCVAGYPHGHPDSPTYEEDLQHLKEKVDAGADFIITQLFFKADRFVKFVEDCRRIGINVP
IIPGVMPIQGYHSLRNLVKLSKLEIPDEIREAIEPIRDNDEAIRNYGVHQAVTMIRELFD
SGLVNGLHFYTLNREVATIQILKQIGLWTEDIQRPWPWKRTANYNRCEEEVRPIFWASRP
KSYVYRTQEWDEFPNGRWESLKRRSSSGENWKEDRGSSESPAFGELNDYYLFYLKPNAKK
EELLDMWGHELTCLQDVFDVFTNYITGKDSKNGKKVRKIPWNDDDLAAETGYINDKLARI
NSRGVLTINSQPNVNAAPSTDPVVGWGTPGGYVFQKAYLEFFTSRENVQALFKVLPKYPN
VNYHIIKYEGEDDYTNCDQQQPIAVTWGVFPGKEIIQPTVVDPVSFKFWKDEAFTLWTEY
WGQLYAENSKSRELIQHIHDTWYLVNLVDNDFPRENILFTVIKDMFAEADLQRAKGKGQT
NGVNGVHHVDDDGVFVNGAGDVPKNTCAEQIQRNAEAEIVQAL
>A0A6I7QVB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MLEDRRPLLLDGATGTELYNRGVFINRCFEEANLTNPDLVRGLHDDYIKAGAGAILTNSW
GANEFKLGAHNLREKTREINERAATLARESAGEDHFVGGSVGPLGRRLEPWGPVTADQAF
AAFRLQVECLLRGGVDFIFLETFSDVMELEQALRAARAAVSDAASDQEPAAAIAASVTIN
LAGELLQGDSLETVITSADAWGADIVGLNCSVGPQPTLTAIERIKGLTAKPLCVKPNAGL
PREVDGRTIYMSTPEYVATYTRNFLQAGVQFVGGCCGTTPAHVKSMSQSFRHFVAMRDTP
TAGNDGKGRVTVEARRASTETEQPPVRRIPLEEKSRWSAKIARGEKVYALELLPPNGVNL
EPVLERTARVRDAGIDAINIPDGPRASSRMSTMLTAVMIEQQVGIETVLHYTCRDRNLIG
MQSDLLGIHAVGLRNMLLITGDPPKVGNYPNATGVFDVDAIGLTNVVHRLNGGIDVGNRS
IGEPTALSIGVAVNPVHRNFEYEMERFARKVAAGAEWAITQPVFDERDMLRFLEHIEKTG
IRIPIVVGLWPLTSLRNAEFMNNEVPGISIPDEVIRRMAEAGSREEALETGVEISRQLHE
RLAPEVQGFQISAPFGRIELALRVARG
>A0A5N1KY87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula sp. CBA1130|TrEMBL
MALGTRAVADSQGVRTLLTSARFELMPFESFDEEITHLPDNATIAITTSPQLGIEKTVEK
TEEAAEMGYDVVPHIAARYVEDREQLEEIAERLAQAGITDIFVPGGDREEPAGEYESALD
LLEALAETEYAFEEVGITGYPEGHDFIDDETLAESMAQKAPHATYIVTQLCYDPDTVLEW
VGDIRARGVDLPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDDEYNIRGIHIYTFNQTPDTEQWRRNRLDT
>A0A4S1XF99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas gei|TrEMBL
MAAPLFADVAGDIEVSFEFFPPKTEKMEETLWESIQTLSPLAPRFVSVTYGAGGTTRERT
HNTVARIARETGIPAAAHLTCVEATREEIDQVAEEYWAAGVRHIVALRGDPPRAGERFQS
HPGGYENAAALVAGLSKLHPFEISVAAYPECHPDSANPTADLDNLKAKIDAGATRAITQF
FFEPETFFRFRDDAAKAGIAAEIVPGIMPVMNFASVQRMSAMCGTAVPAWMGKLFEGLDE
HPAARQLVAATLTAELCRKLYAGDVRQFHFYTLNRAELSYAICHLLGLRPKVGAELVAA
>A0A2N2FUV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-4|TrEMBL
MRIAELLSKGKPFLSLEFFPPKERAEWPAFFATVERLKVLNPLFASVTYGAGGSTQSDTL
EIVARLAREYCLETMAHLTCVGADTAKLTAFLDQLVAAGVHNVLALRGDLPQDASPEIFA
CLPLQNASDLVTFIRATHPEIGVGVAGYPETHPEAVSPDIDLDFLKFKVDQGGDFIVTQL
FFDNQLYFDFVAKARAMGIEKPIIPGILPVVSLKVIKRIVSLCGATVPPVFLQELEIADQ
RGGTDAVRKTGVIFARKQAEELLAAGAPGVHIYTLNHADAVLSLAEGLLY
>Q0GA68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emericella nidulans|TrEMBL
MEKITHKIAALPPGANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCVGVAAYPEGHPADSFQDIQDPKVDLPWL
VEKTQAGADFIMTQLTYDIDAYTEFENLLRNHESGTFKTIPIIPGLMPIHSYKILTRVTK
LSHVKIPPPILAKLDEVKHDDDAVKRLGVDILAELVDGMKKLPTPGLRGFHFYTLNLEKT
VSFILERCKLIPDHDDDAEAVADGVSLLTVDAEIANRRRRASSISSLPHNRVIVDKVSNG
SSKDSVTHEATAASAGLPAGPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFG
EIDGYGPSLHVAPSVAHRIWGYPVSTDDISKLFRRHVSGDLHMVPWSEGGAEENTSGLNA
ETETIRPELLALIDKKGWWTLASQPAVNGVRSDDPIFGWGPPGEGFVFQKPFVEFFCPAS
DFKTTLKPLLQKHGHEKLAWFATNAAGDFESSLPAETSDTEPVEMNPNNVNAVTWGVFRG
KEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKSSATEKFLEKTKNDVWLVCVVGQDFG
AGTEVGSKEEDDEKKWMWRLLADC
>A0A2T7UJV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararhodobacter aggregans|TrEMBL
MPAPRISFEFFPPKTLEASFRLWETVRMLAPLRPDFVSVTYGAGGTTRQLTHEAVTTIGR
EFTLNVAAHLTCVDATRAETLAIAESYAAAGVTELVALRGDPPKGQGGFAARPEGFASSL
ELIAALKDTGKFKIRVGAYPERHPEARDEAADIDWLKQKFEAGADSAITQFFFEAETFLR
FRDRAEKAGIDAARIIPGIIPIEGWAGIRRFAQATGATIPGWLDEAFVKAGRDGHEQLLA
TAVCTELCDTLLGEGVPALHFYTLNKAHLTRDVCFALGVKPQVALQNVA
>A0A5B0APV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces apricus|TrEMBL
MALGSASTRTDRARTVRDMLASGRTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGTTRAGTVKATEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMADWVAHPQGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDTDVANFVD
KCRAGADYAITQMFFQPEAYLRLRDRVDAAGCSTPVIPEVMPVTSVKMLERLPQLSNASF
PDALKERILTVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A2Z3FWY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium fredii CCBAU 25509|TrEMBL
MSPDINPFDPSAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDTIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHEATPTETLVAERLGHLREGIEENQQQLAEAAAH
HPH
>A0A1B9U2G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium rubi|TrEMBL
MTKTEADRHVTENFKLSFEFFPPKNADMDVQLWETVEELSRWHPDFVSVTYGAGGTTKAP
TLVAVDRMISIAGLPTASHLTCVDASKQEVHDVVEELRAIGVKRFVALRGDPSTGPGTAY
KPHPDGYENAAALVRGLRELGDFEISVSAYPEKHPESESDSVDIDMLKRKADNGATRALT
QFFFDNDIFERYMERVTKAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPAFLDDRFEGY
DDDVVGRAKVAADVAAEQILDLQRRGINEFHLYTMNRAPLVNAVLENVGYRPMRKSAA
>A0A2T2T020|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QH_9_64_21|TrEMBL
MKVTEHFDQASEPLISYEIIPPKRGGSAEQMLEVVEELMPFDPPFIDVTSHSAEVEYKQK
DDGTWERCVKRKRPGTIGLCAAIEARFGIDTVPHLLCKGFTCEETEDALIELNYLGIDNV
LAIRGDDKGYEKSISENRSRNEYAVDLVQQIQDMNQGMYLEDLMNAEPTDFCVGVGGYPE
THFEAPNLAWDIMRLKEKVDAGADYVVTQMFFDNEYFFRFVDKCREVGIDVPIVPGIKIM
KRKRHLRTLPKYFHTEIPEELAAEIDAADPEDVEKIGVDWAIRQAHELMEADVPCIHFYI
MSSADTVKKVVEPLREPKEVA
>A0A1Y5HMC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium 56_14_T64|TrEMBL
MTTPEISFEFFPPQNLQASFRLWDTVQVLSPLDPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNASRAETLDIADQFAAAGVRDIVALRGDPPKGAGGFTAHPEGFANSL
ELIEALAETGKFNIRVGAYPDRHPEATSPDADVDWLKRKIDAGSCEALTQFFFEAETFFR
FRDKCAKVGIDHVLTPGILPIENWKGARNFAQRCGTVIPAWLDDAFDKAMRDNREDLLAT
AICSELCSDLLDEGVDKLHFYTMNRPELTRDVCHALGVTPKVALENVA
>A0A2N1JBD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malassezia vespertilionis|TrEMBL
MAESESKITTKLERAKKDGRVWWSFEYFPPRTPQGLSNLYDRIERMAKLGPEFVDITWNA
GGRTSDLTSQLVRTVQAYFGLETCMHLTCTNMPRNKIEVALREAKEYGCRNILALRGDPP
ASGGEWEPRAAGFSHAYELVEYIRNHYGDYFTIAVAGFPEGHPEEESGIEVELEYMKRKI
AAGADFIFTQMFYDVDLFITWVRRLHAEGIHVPIVPGVMPIQNYGGFTRAVARFRAKVPQ
FFHDALDPVKDDDEQVRLVGTKLVGEMCRKILNTTDLDVHGLHIYTMNLERGSQMLLEYL
ALRPSINQLSPLPWKPCLTPKRREENIRPIFWANRSKSYVNRTEAWDEFPNGRWGDARSP
AYGDVSAFGTQLRESKEEALALWGEPQTLDQVKDLFVRFCSGDLARLPWSDAPVAKETRV
IDRMLIELNRRGFLTINSQPAVDGVPSTDSVHGWGPKDGYVYQKAYLEFFVSPQQLDELL
RLIELDPQITYHAVNAQGDMRTNTTSDSPNAVTWGCFPHCEVLQPTIVESISFLAWKDEA
YELGRNWARMYAPDSASAKLLTHMFDSWFLVNVVHNDFKQSLAIFEPFLEARVDGA
>A0A370QF92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacillus tribolii|TrEMBL
MSFYHANQREALNQSLSELHGQINVSFEFFPPRTSEMETTLWQSIDRLSGLKPKFVSVTY
GANSGERDRTHSIIKDIKERTGLEAAPHLTCIDATKDELRTIARDYWENGIRHIVALRGD
LPAGSGKPDMYASDLVALLREERDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTAGIEAEIVPGILPVSNFKQLQRFATMTNVRVPSWMSNMFE
GLDDDAETRKMVGANIAMDMVKILCREGVKDFHFYTLNRAEMSYAICHTLGVRPAQG
>A0A158FDT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia sordidicola|TrEMBL
MKPIELSFEFFPPKTPEGIEKLRATGAQLKTLHPKFVSVTFGAGGSTQQGTLDTVLEMMK
QGLEAAPHLSCIGSSKDSLRGILGAYREHGIRHIVALRGDLPSGMGEVGELRYASELVGF
IRAEHGDWFNIEVAAYPEYHPQARSPKSDLDNFVRKVQAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPKWIARRLESYGDDKETIRAFGLDV
VTGLCERLVKEGAPGLHFYTLNGAAASKTICERLKLQGK
>A0A8J7KR55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Longispora fulva|TrEMBL
MAVNNASFRPARPASIGDLIRHPDPTFSFEFFPPRNAEGEQVLWQTIRELEQLRPSFVSV
TYGAGGTTRDLTVEVTERLATETTMLPMAHLTAVDHSVRELRHVVGRLASAGVRNILAVR
GDPKSGVNGEWIKHPEGVLYAEDLVRLVKESGDFSVGVAAFPYKHPRSRDVEEDTKFFVR
KMKAGADFAITQMFFDADDYLRLRDRVAAAGCEAPIVPCIMPVVAMGTIARSAELSGAPF
PPALAAEFEKVAADPAAVRRLGIDQAGELCQKLLREGAPGIHFITFNRSTATREVWQNIT
GVRAHAA
>A0A1V6KH85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium ADurb.Bin002|TrEMBL
MPENRFKEALLDPSEFPVTWELVPGRGAKEAAQEKCLAQAEQAAGGHKVCALTLTDNPGG
TPAMSADFMGAEILKLGIEPLVHFTGKDKNRNQCESQLYALDRAGVRNLLVMSGDYPVSG
FQGRPAPVFDLDPVHLLQLITSMNRGLTYPGIKGAVTHQPADFFPGAVVSPFKATEAEQM
GQYDKLKKKIAAGAQFIVTQLGYDARKFHEALLFMKQNYPQIPLVGNIYILPFGAAKMMN
RNDLPGSVVTDQLLADIDRERSDPDKGEGARILRAARMYAILKGMGYSGVHIGGHNIRYE
QVEEITRQGEMLVPSWTELVRYFHYPIDNGFYFFEANPATGLNRDTPVDRRSRPLETKVE
CAYGFSRFFHRLMYEPGKNLYGAMRTLCKTVQGTRIEPFFHKLEHLTKVALFDCRDCGDC
ALPDAAYLCPMSQCPKNQRNGPCGGSFQGWCEVYPQQRPCVYVRAYARLKKHGEESRLAG
DIVPPCNWDLYQTSSWINYYLGKDHTSAKQDGAGSPGTP
>A0A8B2QX05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phascolarctobacterium faecium DSM 14760|TrEMBL
MKIIDLLKNEKVCISCELFPPKAGTELQNALNIVSDIAEVGPHFMSVTYGAGGTSVGQTV
AIARAIEASGRPALAHLTCIDADEAKIDDVLAQMRAAGVQNVLALRGDAVNGNDGDFAHA
SDLMGKIKKAGDFCVGGACYPEGHPEAGSLDRDIVNTRRKIDSGCDFLVTQMVFDNNIIY
NYMYRLLRHGIDVPVVAGIMPVTNAKQINRICELSGTKLPANYRAIVEKFADDPEALKQA
GIAYATGQIVDLIANGLKNIHVYTMNRPEIIGGIMKNLSEIVK
>A0A8G1R585|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus piperis CBS 112811|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCKDRGIHVPIIPGIMPIQTYAAFIRRSNWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVDFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFNLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A0R2D210|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus senioris DSM 24302 = JCM 17472|TrEMBL
MEILDWRRFAIIKAINFCKGGLFMSFSIEIVPPSSPDKVPDYEEMLAGLADLQPTSVAVT
LGAGQTTTAKEASLVTLTRVQNQMGLPAIAHLTGLYETKASVTAFLERLRTINVHQIMAL
RGDYQADRQVGDFLHASDLITYLKTQGDFQISAACYPAGHAEADSLAADLQYLQLKVAVG
AERLISQVFFDNQVFYDFTDRAQTAGINVPIVAGVMPILSLHLVEILTTKMGLTLTPTLE
QLVSRYGDDPVAFRQVGLEFTQRQIEDLQTHQVAGIHLFTMNDLAATKALCGLN
>A0A412KBR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium adolescentis|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVDEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREKRPALKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCESRVPEKLAVLLDKWGSDTALLKEAGIAY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A1G2ZAK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RBG_13_60_9|TrEMBL
MKPNSKLASAIQASGFIVTAEVTPPPAADGAAIKAAADVMGNSLTAVSVADNHSGIGMSS
LAASLVLLQLGREPIYQVVTRDRNRIAIQSDLLGASALGIKNVLCTSGHHQTLSGCSESA
NVYDLDAIQVVWAIKQMRDKGTLLDGTAIAGTFSALIGAVVNPYLRPLELNMLQLAKKIE
AGADFVQTQPVFDVDEFGVWLNAAKKEGLTDETAILAGVLPLSTAEEAEKLREAHTELRI
PDAMVAKLRAAGNADAQEKEGLKLCADIIGKLKGMKGVRGVHILSGGREKLVSELRVAVG
L
>Q0YRM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium ferrooxidans DSM 13031|TrEMBL
MVPGRSALSAPASVYFSLQANHCFVYCSFSKKLLNIIFFMLVKEILDAAVKPVFSFEFFP
PKKDEEWETLFKTIAALSPLNPSYVSVTYGAGGSTRSRTHDLVTKIQRETGLTVVSHLTC
ICSDREETGSILQNYRDNGINNVLALRGDKPAGTATLAEAIKDFPHAIDLIRFIKTNYPD
IGVGVAGFPEGHPETPNRLQEIDYLKEKIDAGADYIVTQLFFDNRDFFDFVERCTIAGIT
VPIIPGIMPITTRKGMIRMSELALGARVPAPLMKKVLSASDDAGVASVGIEWATMQVQEL
IDNHIKGVHFYTLNMADATLRIFNNLHQ
>R5X4N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium bartlettii CAG:1329|TrEMBL
MSKLREAFEKGEFAITAEMAPPKGTDLSHLAECAKLVIGRVHAANVTDNQSAVMRTSSLA
TCKMLKDLGLEPVIQMTGRDRNRIAIESEMLSAGFFGIDNLLALTGDHVCVGDHKQAKPV
FDLDAVSILSTATMMNNGTDSTGLELKGKTDFFLGACVTPEYDPIEVQLLKMEKKIKAGA
KFFQTQAVYDIEHMRKFRELTKDMDCKVMAGIVPLKSPGMAKFMTANVPGIFVPDDQIER
LKAAGKGNYVAEGIKMAGEFIKQLKEENLCDGVHIMAIGAEENVPLILDAAGL
>A0A437KRY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. CNPSo 2736|TrEMBL
MRSETARRDGDIRLSFEFFPPKNPEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPTL
DAVRRMIGDSHLATAAHLTCVDASREDVHQVIDEFRNAGVRHFVALRGDPSTGIGTAYKP
HPEGYENAAALVKGLREIADFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQF
FFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYDD
DLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDSVLENLGLERLRRSAA
>R4V7Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spiribacter salinus M19-40|TrEMBL
MLPSDRRAEIAQAALGFSIESMPRDAARITDFRDHLPVGTEVYIAWPPRADLDEMIQAAT
KLHEQGMIPIPHVAARRVESQAVLRDFVQRLTEEAGVKRLLLLGGDPDTPVGPYPDASSL
LTSGVLSAFGIEAVDIAGHPEGHPVMQGDEPARVLQEKIALAQQAGIAVRVVSQFVLEPD
AVVDWHTQTYREAAGETALQIGVPGVVSTRRLLQLASSCGLSGSLGMLRKSGRRLAKTAM
GHDTTEVLVASLAHLVNAEKSVAGFHFYSFGNFEKTAAWACSVTRGDFDIKGDAIQLN
>A0A1Y4DUL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. An271|TrEMBL
MRIDQIFADARTAGAQPVSFEMFPPKGELTLERAREVAAQFATDGPDFISVTYSAGGSGN
SDATARIASMISTEFGIPSVAHLTCISLTHDTLAEKISEFRAAGVENVLALRGDLPAGMS
EAEAGDIAFPYAKDLIPALVNAGFCVGGAAYPEGHLTCDDLPTSVKHLKQKQDAGAGFFV
TQLFFDNDYFYRFLELADAAGITVPITAGIMPFMSKQQITRMVFTCAASLPSPVIKILAR
YEDDPESLRQAGIEYACRQLEDLKAHGAEGLHVYTMNRPDVARACMSALRI
>A0A7H4PCN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella grimontii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRTIAKDYWDSGIRHIVALRGD
LPPGSGKPDMYALDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7K1NT93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. GA104|TrEMBL
MSPPSLIETHPNLSDAAPVALSYELFPPRSPAAAETLWTTIRELETTAPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIIGELLDTGVRGILALRGDLPRD
GGEPAEGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLLTRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAPELLERMAAADSDAERMRIGVSATVDLANAALEAGAPGIHLYTFNEHQSALDVLDKLA
LPRRTRSSRREAVAGQLAS
>A0A2S9JXJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium myrsinacearum|TrEMBL
MTKIAASIEVAARQAIDSQDLPGLFPEGTRVYITDMGTDGVDTLTAAAKRIHDLGYKPVP
HFASRRLGTRAALETRIRRAAEEAGVTDVLVIGGGLERQAGEFSSTMEVLETGFFDKYGI
TEMGVAGHPEGSPEFSEAVALEALRLKQNFGERTGARLRVVTQFGFDAERFIRYSESLRE
HGVDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNALSLTALATSHSPEGVVGPIE
QHVINNPASAIKQIHIFPFGGLKKSSEWLVDRGSWTVASAQYASAASK
>A0A832PHK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfovibrio thiophilus|TrEMBL
MTKLKKKLQDGKFVITAELTPPKGPETSKIIQKLEELKNLVDAVNFTDNPSATMTMSSTA
ACKLSLDLGLEPVLQMTCRDRNRISIQSDLLGAYALGIRNLLVMTGDHTIHGDHKQAKPV
YDIDSSILIKLVGNLNKGLDINGNKLNGKTDFFYGGVVNPNAEPLIPQLKRFEQKWRMGA
EFFQTQMIFDIKRLEKFMEYAAKFETLVIAGIVIIRSKKMLNYLVSNIPGVVVPQWLIDR
IEGLKDEDVKKFGIEFASSTILSILERKLCNGIHIMAFSRVEEVKNLLDFIRI
>A0A135YN39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pasteurianus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADTIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAREAAGDDAFVLGTVGALRGLKQCNLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEVELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLTITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKEANFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDGLADLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALEHFKGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A3E2HJZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scytalidium lignicola|TrEMBL
MADFEYISQSSAIPPVEGKKAPLDFSHHFSRVTKNRVESSVKQFYKFFAIPGIGNLAGGL
PNASFFPYDTLEAQIARPERFLPTPNGPSLVANAQKRHPFTSKTPKTDASSHLTVPHASS
TANPLQKIDLTTALQYGQAQGYPPLYSFLRQFTRENLHPNVPYLDGPDIILTCGSTDGFA
KSIEALSNIWCEDRDWIREREGILCEEFAYMNAIQTARPRGLQVVPVKIDLEGMSPYGKG
GLEDVLENWDESKGKRPHLMYTVTIGQNPTSGTLSVQRRKEIYALCSKYDVMIIEDDPYW
YLQFPSAANLEAQARGTPPPPPQPVHTFEKSSGYDYLDSLVPSYLSVDTDGRVIRLDTFS
KTVAPGCRLGWITAQPAIVERILRITESSTQQPSGFVQSMIAELVMGPQPGVQFTPKSKA
EALTFSGWQTAGWVRWLEGLRGSYERRMNRMCAILEDGRFQVKQGTPLKASEQDWAVISK
TELYSFDWPRGGMFVWVHINFPSHPLFGIVEGPKMADALWLFLASRPYLALVSPGKIFSP
TPEILAEKGWQYFRLCFAAVTEEEIEATSKRFAAGVAAFWKIKTKKELDDIIDDPTEINA
IQEGVADLGLNWLKIPPATALLVPRRGFCPGTPLIMEKITDKIAALPPNSNYFSLEFFPP
KTAMGSSNLRARLDRMSRALRPLFVTVTWGAGGSTASKSLELAELCQRELGLTTCLHLTC
TNMSKALVDHALEEARVLGIRNILALRGDPPRAEEYRAHDGKDEEGSPEKEEFEWAIDLV
KYIRQQYGDYFCVGVAAYPEGHADEGDPAGQSPEHDLPYLVEKVQAGADFIMTQLFFDVQ
AYDGFEKTLRDHPSGAFKSIPIIPGMMPVQGYQMIKRTTKLSHAKIPPSIMARLDEVRGD
DEKVKNVGVNVISEIIEHLKYQKDAAKGPRGFHFYTLNLEKAVSFILERTNLIPASTPSE
PGDETAVLDTLLKPPIAEDRANGMQVNGTSSGSNRRLSSVGSDPRNHVIISSKVSNPEFE
VTPYEASVLAGPVNTRANTLAISEGEGSLGREATWDDFPNGRWGDARSPAYGEIDGYGVS
LHMSVNQAIRLWGYPTTVKDITNLFIRQLEGSLTAIPWSEEGLNEETNTIKSQLLKVNQK
DWWTVASQPAVNGVKSTDEVFGWGPKNGFVFQKAFVEIFLPSQDWKVLHEKLTSPGIRDQ
VSFYACNAAGDFYSSDNAASLNSTEQESSSTNAVTWGAFPGKEIITPTIIEEVSFKAWAE
EAFGIWKEWGRVYSPKSKSRELIDEMVGDRWLINVIHHTYVEPEALWDLLLS
>A0A846M6H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium vermicomposti|TrEMBL
MNKPVIHPNWDRPALNMVDGYSIEMTAKDVESLRAAAPAMAPETPVAVTFLPGETLSARL
DAIKLVRARGFEPMPHFSARRIASAAEFEEYLAAATAQAGVKRCFVIAGDPSEPEGPFFD
SSALIGSGAFERMGVTAIGIGGHPEGHPNMSEEQCWSVLEAKCAEIERRGMAPLIVTQFA
FDGERVLEWLRALRGRGIDAPVRIGVPGPAGIKTLIRFAARCGVGASAAVLAKYGISIAQ
LFGSMGPDRLVASLARGIGPDHGRVRLHFYPFGGLEKTIAWINGYDERP
>A0A353ZP55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp|TrEMBL
MSPPSLIETHPNLAETAPVALSYELFPPRSPAAAESLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPEELAEIIGDLLDTGVRGILALRGDRPKD
GAPPVAGSLHYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYANLISRARRAGVTIPIIPGVMPLTSLRRVTRLG
>A0A1G3UPL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium GWC2_56_13|TrEMBL
MKTNSVIEKVLEQGGFVVTSECGPPRGADPEVVRRKGELLRGVVDGVNVTDNQTSVVRMS
SLSACAILKGMGLEPILQMVCRDRNRIALQSDLLGAAALGINNVLCLSGDHQKFGDHPQG
KNVYDIDSVQLIQTVARLRDEGKFLGGDEVKGRPMLFVGAAANPFADPFEIRAARLGKKV
KAGCEFIQTQCIYNVERFTRWMEMVCERGLHERCGILAGVTPFKTAGMANYMKKNVPGMD
VPDDMIARMKGVAKEKQAEEGIKICVETIERLREIPGVRGIHIMAIEWEEKVAEIVKAAG
LLPRPEIQ
>A0A3D6DXW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter sp|TrEMBL
MTDHIPTFSLELFPPQTPEGSEKLRAARARMALLKPRFFSVTFGAGGSTRDRTLETVLEI
QREGHQAAPHLSCIGSTRDSIRSILEQYRAQGIRHLVALRGDLPSGMARPGAFRYANELV
EFIRTETGDWFTIEVAAYPEYHPQARSPQDDLLAFKRKLDAGANSAITQYFYNFDAYAHF
VDQCQTIGIDVPIVPGIMPISSYSSLARFSDNCGAEIPRWIRKRLESYADDSASIRAFGL
DVVTGLCERLLASGAPGLHFYTLNQDALTSTLWQRLRLS
>A0A0D6JC66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Filomicrobium marinum|TrEMBL
MTEMPVDIEERSILSHEMRHSTLFQDISIELLPEQVDAFLPKAKCFPENSLVFLTHIPGK
PISAQAEAAKKIHNKGFVPVPHLAARNFTSADEYAGHLRTLASIGVTTVLVLGGNPSSGT
PPLRFAADLLRHPVLNDVQLKKVFIAGHPEGHSVIPKDALIPALKEKISLVREWGAQPEI
VTQFAFNGEAMAAWAAELRTQDINAPLRFGMAGVTSLPKLIKFAAMCGVGASLNALKRQG
TSLIKAMRDQDPGDIIAELDSSLSQRGIKDVTLHFFPFGGWEKTLKWIDMQSTE
>A0A2N0XAE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium mastitidis|TrEMBL
MSTAHLYAGYRPGVPTDTPTVSFELYPPRNPSRGSGVWAGISRLIDTAPDYVSVTYGAAG
KRTDTRDRSVQVLLNVLDRHRDLPAVAHLTCLGSTRAELTLLVRLLLRAGVRDFLALRGD
PPGGDPDYRPPADEPARAVDLVRLIREVAAQELPLGMGRGYNGAGAATAARPEDYVSIAV
AAYPATGGRARANDIAALAEKEAAGADYAITQVFYSEEDYASMVRELRMVGSRLPIVPGI
MPLHDLNRLRAMERLAGIPVPKRIERIFTQATSPDRLVRDTLSATVDLIGGVLDAGAPGI
HLYTFNRPRPTLDILEYLRASGYLGRSAGPRAPRDPAVDTELVSLALHRMTPSYY
>A0A2T1EAP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|filamentous cyanobacterium Phorm 46|TrEMBL
MNRFRTACTTPGEFIITAEVAPPKGGDITHTIAMAELLKNRVHAINITDGSRAVLRMCPL
AVSAILLQHGIEPICQVACRDRNQIGLQADLMGAHALGIHNILALTGDPVKAGDHPKAKS
VFDFESVRLLQVIQKMNGGSDWNDKPLTDGVTDLFVGAAVDPQSPSWSGLQSRFEKKVEA
GAQFFQSQLITDFEVFDKFMHHIAAGCNKPILAGIFLFKSAKNAEFIKKYVPGVHIPQDT
IDRLAKSPAPLQEGIKIAAEQVKLARQLCQGVHLMAVKREDLIPQILDLAGIEPLS
>A0A8J7U0K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sciscionella sp|TrEMBL
MTTVIERLRAGLRPAFSVEFFPPRDDADERVLWRAIRELEPLDPAYVSITYGAGGSSRDR
TVRTTGRIAGETTLVPMAHLTAVNHSVAELRNMIGWYAAVGVRNILALRGDPPGDPMGEW
IAHPNGVHYAEELVELVRELGDFCVGVAAFPYGHPRSTDFVSDTEFLVRKFRAGADFAIA
QLFYRADDFLRLRDRVAALGCDSPIIPGVMPITTKRTLAKIEEFSGEKIPPEIDEKFAPY
SDDPAAFRAAGIDHTTQLCARLLSEGVPSLHFYTLNRSKATREVVARLGMAGVRA
>A0A7W6N7F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga flocculans|TrEMBL
MSPLTLRPSRQASRPIKVSFEFFPPKSPEMEATLWSSIQRLAPLNPQFVSVTYGAGGSTR
ERTHATVSRIVKETHLKPAAHLTCVAATKEEIDGVIRSYWDAGVRHVVALRGDPVAGIGT
AYEPHPADTGRPAISWRASRPSAISRSPSPPIRRSTRRPPRSMRISTC
>A0A8I0XFS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. NZS100_1|TrEMBL
MALSLKEKIEDTKQGVYLIGTTPPKIGTDKAQLKIIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQDRPFAFKQTVDPREYSHLIRNLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDL
QNVVLVGSPSSVGDIKLSLPDAYKALAEQSDDFFLGGVTIAERHLSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQDITPQRIILTFTPCGGEKTLDFMKWLGISV
PEATKWRMLDADNTLSESVRICRENLDLIIKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKATMELNLAEKLIA
>A0A6L5GAU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycomyces albidus|TrEMBL
MTLGTPSVMPQQVAKVGDLLRSGTPRFSFEMFPPRSEKDEGILWRTLRNLEQLGPDFVSV
TYGQGGKTRDKTIETTDRIISDTTLLTMAHLTAVGHTVAELRNLIGHFANVGVRSILALR
GDPPGDPRGEWVKHPGGIEYARELVELIKESGDFSVGVAAFPEGHPRDVDWETGVRHFVD
KCRAGADFAITQIFFAVEDYLRLRDAVAAAGCDVPIVPGIMPITNIKQIERFAVLTGMAF
PEDLAERLRAVEDDRDAIRDIGVETATVMGDRLLAEGAPGLHFTTLNHSRSTRRVWRNLR
G
>A0A809SBP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuriferula nivalis|TrEMBL
MTARTFSFEFFPPKTPEGMDKLRDVRSQLATLHPKFFSVTFGAGGSTRDHSLATVLDIQH
AGLEAAPHLSCIGSTRDNIRAILGEYQSNNIRHIVALRGDLPSGMASAGEFRYANELVEF
IRNETGDWFNIEVAAYPEVHPQAKSAQDDLMSFKRKMDAGANAAITQYFFNADAYFAFVD
DCAKLGITAPIVPGIMPIGNFSQLARFSDACGAEIPRWMRKKLEAYNDDIDSIRAYGLDV
VTALCERLLANNAPGLHFYTMNQSAATMEIWRRLGL
>A0A8H4S6A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium sp. str. #12|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKALGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRQTHGDYFCVGVAAYPEGHPADTFQDVQDPIRDIPY
LVEKTLAGADFIMTQLTYDIEAYQKFEHALRNHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIARRMEELKHDDDAVKRAGVDIVSEIVGGIRDIPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPSYSDAGELAIEDDPASIPLDFPGRALRRRRASSINSQPHNRVIVDKL
SVHESSQDSVHEALADSAGVPAPPPNRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTANSARRLWGNPVDSKDMSTLFRRHVSGDLHMVPWSEGGAEEDGDG
LNAETELIRPELLKLIDGRGWWTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFC
SSNDYTNILKPMFAKHGHDKLTWFATNIKGDFESSLPTQPADVELDDLGSNPESVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPSETYLDTTKNDSWLVCVV
GQQFGAGTKRGSKEEEDEVKWMWRVLAGEEA
>A0A7K9WZ81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psophia crepitans|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAADL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAISAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNKRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A854D2F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parainfluenzae|TrEMBL
MSYANEINTLNQHLADTNKKINVSFEFFPPKNEKMESMLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGIEAAPHLTGIDATSEELKEIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDNYLRFRDRCASIGIEAEIVPGILPVTNFKQLQKMASFTNVKIPAWLAKAYEGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHTLGIRPTTNP
>A0A0E9NLX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saitoella complicata (strain BCRC 22490 / CBS 7301 / JCM 7358 / NBRC 10748 / NRRL Y-17804)|TrEMBL
MKISKKLQESIKEKRPAWSFEYFPPKTAVGVRNLYDRMERMYELGPEFIDITWNAGGRLS
NLTCEMVATAQSVYGLETCMHLTCTGMPREKVDEALEDAYKAGCQNILALRGDPPRDVEK
WEQTDGGFRYSKDLVKYIKDKYDDYFDIAVAGYPEGHPDDEEDADANIRYLKEKVDAGAT
FVITQMFYDVDNFLDWVKRCRKAGIDVPLIPGIMPIQSWDAFLRRAKWSGVKIPQHFLDA
LEPVKDDDAEVRLRGTKLMVEVCKKILDAGIYQLHFYTMNLEKATKMILEGLECEASPGD
LPWKPSLGLKRKEENVRPIFWKNRHKSYIARTEEWDEFPNGRWGDARSPAYGGLDVYDGL
LKCSNEEAHKMWGYPTSIGDVGDLFARFCEGEVPQLPWSDSAITEEAASIRDALVKLNRH
GFITVNSQPAVNGVKSTDPVFGWGPKNGYVYQKCYLEVFVHPDQLDLLIQNMSKEDEITY
YAVNKKGDLHTNTTSDEPNAVTWGVFPGKEIIQPTIVEIVSFMAWKDEAFRLGTDWARCY
APGSESRKLIEDVMDTWYLVNIVHNDFHEPCKIFEVFETIEPVVGHTNGVNGDHGTNGYT
NSAANGIVEACEKVSLN
>A2BNU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus (strain AS9601)|TrEMBL
MKSKLQKTLEKKSKVITAELMPPRGGSPIRSLKIAQLLKDKVHAVNITDGSRAVMRMCSL
AMSKLLLENGIEPVMQISCRDRNKIALQSDILGANALGIRNILCITGDSVKAGDQQNAKA
VHEFESVRLLQQIQAFNKGIDPTLGELCDKKTFIFAGAAADPNCRNKRSLENRMRKKKEA
GAGFIQTQMVMEKENLIEFCEKISKPLEIPVIAGVFLLKSYKNALFINKYVPGANIPENI
LKRLKDAKEPLQEGIKIAAEQAHDFMNIANGVHLMAVKAEHLIPEIIEKANLSLEY
>A0A662F2R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Acetothermia bacterium|TrEMBL
MTALEQALTKGEFAVTAEVAPPKGTDVSEMMENAEFLRGKVHAINVTDQQSSVMRLGSLA
SCHLLKEAGFEPVFQLTTRDRNRIALQSDLLSAYALGIENVLCLTGDYVTLGDHPQAKPV
FDLDSVSLLMAAKSLENGTDMAGESLEGAPSFYLGAVVTPGYEPLELQLLKMERKIKAGA
QFFQTQAVYDPEVFRRFMESAKEFGVPVMLGCVLLKSAGMARYMNKNVAGVSVPDSIIDE
MKKTDDKVTTSIKIAARIIRETKEMCQGVHLMPMGWERHVPDILDEAGIAI
>A0A2X1TN94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morganella morganii|TrEMBL
MMNGISFEINAVSENNNGVELLKSLIEFTETLNPLFYTVNTEIGMMPQAATFDTCMALKQ
YTGRKTIPHIAINNKDECELDCILSRYINAGISSFFLIRGDKHIPGAEKSFNYAIDLIRY
CRENFREAEIRAAIYPDFHKETVSPAEERYWIKEKAGFGIREFICQFCLNSDAISHLKQT
GGHDIRIVPSLFPLVNFSFIEKFTKANGIGYPSWIRKTISDPSLVSVTDEGIALTRFFIR
SALSESGRLHLFTLNNPDLLKKIFSETV
>A0A0Q4S7M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. Leaf78|TrEMBL
MNAASAQGTGFPVSFEFFPPKTPEGAEKLRAARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREELAQLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLKAYVAKVQLGADSAITQYFYNSD
AYFRFVEEAKRLGADVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASI
KAFGLDVVTDLCDRLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A433ZY13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morganella morganii|TrEMBL
MSFLHIDQHEALNQNLAELAGRVAVSFEFFPPGTPEMEKTLWQSIERLSALKPKFVSVTY
GANSGERDRTHSVIKSIKEKTGLIAVPHLTCIDATRDELKTIAKDYWDNGIRHIVALRGD
LPDSSSKPDMYAADLVSLLKSVADFDISVAAYPEVHPEARSAQSDLINLKKKIDAGADRA
ITQFFFDVSTYLRFRDRCAAAGIDVEIVPGILPVSNFKQLQRFAGMTNVRIPGWLGTMFE
GLDDDPESRKLVGASVAMEMVKLLSREGVKDFHFYTLNRAELTYAICHTLGVRPAACVA
>A0A522G8E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp|TrEMBL
MAAFSFEFFPPKTDEQRAQLDQTAAQLLAWHPDYVSVTFGAGGSTLSYTAETAQHLKQTH
GLKVAPHLSCMGGSRAEIAALLDQYRTAGFRRIVALRGDLPSGMASPGDFRYAAELVRFI
REHAGDQFHIEVAAYPETHPQAENAHADLRNFKAKVDAGANGAITQYFFNPDAYFRFVDD
VRKLGVNVPVVPGIMPIANYSQLQRFSDMCGAEIPRWIGKRMQAHGDDAASIRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRVRATRAVLEQLD
>A0A7K1DFV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTSLSTEKRYPDAVEMRSVKSGGTKALTYSFEFFPPKDVEGEERLWAAMSQLESIAPDFI
SVTYGAGGSTRDRTIRITSEITARTHIPTVAHLTCVGSTRNELVDILSKYRDAGIKSILA
LRGDPTGGPRAPWSATEGGLNHADELVTLAAEFGGFTIGVAAFPDGHPSSDGDINKDVQV
LLEKEKRGATFATTQFFFEVDKWKSLVDKLAAKGSSLPIIPGILPVTNVKQLNRMAELSG
TPIPAHISESFAKIEDDADAVRALGVEIATKLCQDLLEAGAPGLHFYTMNTSSATREIYS
QIKDER
>A0A6I3BPP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGTKLRATSFSLEFFPPKDEAGEQRLWLALSELAPLAPDFVSVTYGAGGSTRDRTIRVTS
EITKRTQIPTVAHLTCVGSSKDELIQILNQFKNSGIKSILALRGDPVGGPTAPWEPTPGG
LNYAQELVEIAVEMGFKVGVGAYPDGHPASNHDLAKDITVLLAKERAGASFATTQFFFEI
DKWQAIVDKLAATNSSLPVIAGILPITNVKQLNRMVQLSGMQVPDDIAEKFAKVADDADA
TRKLGVELATNLGAELLRRGAPGIHFYTMNSAQSTIEIAQNLGLIKND
>A0A6I3CK48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNQQSTLGPRKSLLPRPTISFEFFPPKDDQGESNLHATIEALKKFSPDFVTLTYGAGGST
RDRTVRIAAEIILRHQIPTMAHLTCVGSTRDELTEILREYTKAGVKDLLALRGDPVGGPT
SEWISTPGGFDYADQLVDLATKVGGFNVGVAAFPDVHPASHGNFQQDIDVLLRKEELGAT
FAITQFVFDSERYAQLLFTLRDRGSKLTLYPGIMPVTNYMQIVRMLELSGGTMPSATRLK
FARYQNDPASIKELGIEVAARICEEVFEVGAEGFHFYTLNSALATSQVVSALSMLNFSS
>A0A7W0ZGS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDEGRRPTTRLVVRERELVVTAPKLGHETLLQQKLRTGEFVVSVEIDPPRGGNAQAMLEL
AKTLKDSGHVDVVDVNDNPRARARMSGLIASATIERVAGIETIPHLTPRDSSIAGLESML
LGAHAEGIRNVLAVTGDPPEAGDYPGAGGVYEVDSIGLSRIITSMNAGEDFNGREIDAPT
SFFLGVAVNPAADDLDEELERFEQKLEAGAQFAMTQVLFDFSYLDRFLARLGRPCQIPLL
IGIFYVRSHQLALRLHNEVPG
>A0A2L2KWX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas monteilii|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7K1E370|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDFSLLQASRATSKPTFSVEFFPPKDEAGEQRLWDSLSLLAENDPDFVSVTYGAGGSTRD
RTIRITAEITARTSIPTVAHLTCVGATRSEVDAILTRYKESGIATILALRGDPPGGPSAE
WIQTPNGFNHADQLVELAVERGFTVGVAAFPDGHPASGGETARDVDVLVRKFELGASFAT
TQFFFDVSKYQELRDRLSAKGVDRPLIAGILPITNFKQLIRMAELGGTPLPKVVIDRISR
FQDDPDSLRKEGIEIASELASDLIGVGAPGLHFYTMNSAHSTMEITARIGLR
>A0A8J6YS78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermicanus sp|TrEMBL
MGKFFEKVRKGETSIVVELDPPKSPDLSRYLRGAHALKEAGADAITIADNSLSHSRVANM
AVAKRLQDEVDIEGIVHINCRDRNLLAQQSYLLGLHVLGITNLLIVTGDPVKMGDMPHTK
SLFELNSIGLMEKVKKMNEGILFTGVKQEERTRFLYGGALASGKNHIPHRGRMMKKVEAG
ARFFFTQPVYSQEAIEALGKFSREMNPEIPVFLGIMPIVSHKNALFLKGVPGIFIPDEHA
ALFSGKEGKEAEKVGIELAYSLIRYGKKWFNGFYLITPYLRYSITAELTRRIKEGI
>A0A7W0NMW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPDFGTETMARLLANPVLEVFPSSGIEERVAQLPEGSRISVTCSPTKGVDATLALSGWLR
GEGFTVVPHLSARLVDDHHHLDAICRRVTELGIDEIFVIGGDVKQHAGRFSSAYELLAAM
AELGHGFDEVGIAAYPEGHPWLPDETLWQHLLAKQPLATYMVTQMCFDPGAILAWIDRTQ
REGVALPVVIGLPGVVQRRKLLGLSLKIGVGDSTRFIAKHADLTARLMGSGRYSPEDLVT
RLVLDAERQGLPLGGLHIYTFNQIDGTERWRRQMLRSLGGERGAGT
>A0A7K1DXC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVVRTSYSLEFFPPKDGEGELRLWSALEELEHIAPEFVSVTYGAGGSTRNRTIGVTEEVT
HRTKIPTVAHLTCVGSSRQELISILHMYRNAGIRGVLALRGDPAGGPRAPWTPTSDGFTH
ADELVQLIHEFGGFDIGVAAFPDGHPSSLGDSKKDVDVLLRKEHLGATFATTQFFFEVAK
WEQLVYALQARGSKMPIIPGILPITNVKQLHRMAELGGTPIPPSVSEAFSKVEDDSDAVH
ALGIELASNLCEDLLRAGAPSLHFYTMNSATATNQIYRNLNNAH
>A0A2T4KBG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus devriesei|TrEMBL
MSRLLNQLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVERIHRSYIQAGTDIIQT
NTYGANFEKLKAFGLEHKVKEIHKAAVQIAKRAAKPDTFILGTVGGFRGLKQEDLPLSTI
QYHAENQIDTLVEEGVDGLLFETYYDLEELSNIVTVTRRKYDIPIIAQLTASNTNYLVDG
TEINEAFKQLVECGANVVGLNCHHGPHHMQRSFSHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIAYIKSSVKDLKPVNDKKVIPINRKT
NHSRTHTYKHNLTTKVKNGPTVIVELDTPKHLDTDLFFENVGKLDEANIDAVTLADNSLA
TVRVSNIAAASIIRQRYDIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGASNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMSYFITQPVYSKEKIKEVYEATKHLNTPLFIGIMPIASYNNALFLHNEVPGI
KMSEYVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQRVDYSLELAAY
SKAITQNKEAIS
>A0A7V2DY99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTAPAPGGARATGRLARILADGAFAVTAEVVPPASADLGAVTDQARALVGYADAANVTDN
PRSSAHMSPLAGVAAVAAAGVEPIVQLTCRDRNRLALTADLLGAWALGARSVLCLTGDPA
STGDHPEALEVHDLAVTDLVRLAVRLRDEGRLLSGAPVDPAPRYLVGVADVPLARPYDPG
RLDRKLDAGADFVQTQIVFDVDGLGEWADGARARGVFERARVIVGIAPLRSARQARYLDE
QLPGVVVPPELVRALEEAGPDAAATGVRLAVGILERIRQVEGIAGVHVMGLGREDAVRRV
IEAAGLVPRPTLAGAQPRSSIGT
>A0A1Y1L3U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photinus pyralis|TrEMBL
MEMLSAVIHRASITNEKIISIEICPKRKLDVDELNKLRPTFCSIVWHYDGSEIEHIPALV
LLKKLSIHSKRLLLHVPGNCLSQTDVEKVLHSLKSAQVPNVLVLQGASSATQSCKHFVYA
IDLIKFIKRIYGNYFTIAVAAYPNCHPNSATEWDDLVHLKKKVHFAYLTILQIEFRWMQE
>A0A6I3BWH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNSKLRGTTFSLEFFPPKDEAGESRLWLALSQLQPLAPDFVSVTYGAGGSTRDRTIRVTS
EITKRTSIPTVAHLTCVGATRDELVEILNQFKNSGIDSILALRGDPTGGPTAPWQMIPNG
LNYAKELVELAVGMGFKAGVGAYPDGHPASNHDLAKDIEVLLAKEKAGATFATTQFFFEI
DKWQAIVDKLAKAGSKLPVLAGILPITNVKQLNRMVELSGMKVPTAIADQFNKYADDLEA
TKEIGIEIATNLGAQLLKRGVPGLHFYTMNSAQSTVAIAKNLGLIK
>A0A7K0KY75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGHAVTVPSSLMSTRPTISIELFPPKDSAGEERLWSAIASLREISPDYVAVTYGAGGSTR
DRTIRITSEITARTQLPTVAHLTCVGSTRDELIDVLNKYKSAGIRSILALRGDPQGGPSA
AWTATPDGLDHADQLVALASEVGGFTIGVAAFPDGHPASQGNFDRDIEVLLRKEDLGATF
ATTQFFFTAEKYFDLVERLRSRGSHLTVMPGIMPISNVKQLIRMAELSGTPIPSDVEQKF
LALDGDSDAVRDYGRELATTLCQKLLAGGAPGLHFYTMNTSTATKEIFENLGL
>A0A7V3BSN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSAPASRLEAIVRSGRFAVTSEVVPPRSADPAPATAQARELVGYADAANVTDNPAASAHM
SPLAGVAAVARAGLEPTLQLTVRDRNRLALTADLLGGWALGARNLLCLTGDPIGIGDHPD
AAPADDVSVHDLVRLAVALREEGRTLSGAEVSEPPRYFVGVTDSPLAPSYDPARLGSKLD
AGAMFVMTQITYDLDALASWADVLRARGVFERAAVIVGVAPLRSAKQARYMAERLPGVSV
PPPLVAMLEEAGPDAEAVGTAQCVEIVAGLRQMPGVAGVHVMGLGREHAVRHVIERAGLL
PRPAVDA
>A0A7V9SNZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARIDELIARGRTFSFEFFPPKTDTEQDRLEQVLHELEPLNPSFVSVTYRGGRSSRDRTT
NLVANLERETSLNPMAHLICVAHTRDELVEILDDFKAAGLDNVLALGGDPATDADAIEGE
LTYGEELVDLAREVGGFA
>A0A832XUD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poseidoniales archaeon|TrEMBL
MRFRDKVKKPRRPVVVYEILPPREQDGTLSSYAERISSLLSQTHIDAINIPEVHDEEGRG
NRPVQNQLRAEPREFGRLLQDNVGVEAIVNRVVVHEPMAAQQQWLKETYYDYGIDNLVIV
GGESHETSYPGPGVTESSRYITRELNGNRFDYFCGGIAIPSRKAESRRLLEKSRHGIEFF
TSQVLYDSKKIRKVLGHYQQRCDAEGTFPRRILLSFAPVSSPKNVEFLKWLGVEIPAKTE
KYLLEAPDEMAQRSTEIASGIMREILDHVSEAGLRVPIGLNVEHIMSYNFQASITMLQEL
ARDYREFCIRTNLYG
>A0A7Z2KII1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas monteilii|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSTERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DGDKHQEAMHWMRRQATPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETVQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQARIHTLDQWAPA
WRASWQMPGLPAVTFHPPQAGWRQGESRVDASLKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQRLWSTPVGAQVLHKVERAVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFQAATP
RRLSPQPAPRSQPES
>A0A538BMH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTRPPGRLAALLARGSFTVTGEIVPPKGASGDPVSEHARGLVGYVDAVNLTDNPVASAHM
SPLAGVRFVADAGIEPTVQLTVRDRNRLGLTADLLGAWALGARNVFCLSGDPVHVGDHPN
AAVVADLAVGEVIGLARRMRDDGTTLANTELADPPRYLIGVADVPFAEPYDPSRLESKLD
AGADFVTTQIVYDAERLAGWADAMRLRGLFERAKVIIGVTPLRNAKQARFMDQKLPGVRV
PSPTIAALDAAGEDAGAIGMDLTVQLVEAIQTIPDIAGIHVMAMGHDAVTRDLVERTGLF
PRPTV
>A0A417XJ72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium OF09-1|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGKDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKAAEI
>A0A537W9Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDEILGGDGPVFSFEFFPPKTEEGERNLDAALAELRTLEPSFVSVTYGAGGSTREKTI
EIVKRIREQYGLEAMAHFTCVGATVPQLRDTLDEMRGAGIDNVLALRGDPPAGEEQWTAT
>A0A2N5KEM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKQRTTGDQEAREAVAEALRRPRYEVIPLRGAEEQVLEHVPKHIKLTVTASPKKGVGGTL
ELAEQLSKQGYEVSPHLSARLIRDEAHLEDVLARLRESGIRDVFVVAGDAEEPAGKFAGA
GELLAAMSSLGHGLDEVGITGYPESHAFISDADTIKAMREKEPHATYIVSQICFDAEVIA
DWARRVRGRGVELPIYVGMPGAVSRQKLMRVSAGIGLGESARFLKKYGNWFVRFFMPGGY
SPDRLMERLTPSFADPRGNIRGFHIYTFNEVGKTEAWRREVLDRIGATPREERHKESIV
>A0A4R9QSN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2D.F.Ca.ET.232.01.1.1|TrEMBL
MNQFRFSRRPDIGEKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVIREFVDFGVTRFVALRGDPAAGVGT
IYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLGNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
AGSAAA
>A0A443KBD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinirhodobacter populi|TrEMBL
MTNTTDQKPQATNVPAVSFEFFPPQTLDASFRLWETVQALAPLRPDFVSVTYGAGGTTRK
LTHEAVATIHKNYGLTVAAHLTCVDATKAETMEIVEAYHQAGVTEIVALRGDPPKGAPRF
TPHPEGFASSIELIEALARDGRFTIRCGAYPEPHPEATDPLADVRWLKRKTEAGATSAIT
QFFFEPDTFFRFRDACLREGITAKLIPGVLPIQSWKGVKGFAARCGAHVPAGLESRFEAA
IRDGREQELSVELCVDLCEKLMAGGVDHFQFYTLNRPQLTQKVCAALGVTADRRLAVA
>A0A410UPK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. 17J80-10|TrEMBL
MTNSSSVQSNFSIEFFPPRTAEGVEKLRAVRTQLAVLKPAYFSVTFGAGGSTQAGTRDTV
LEIRKEGHDAAPHLSCIGRSPEELRAILAEYKAHGIRRLVALRGDLPSGYGAVGSNGHEF
HYASELIEFIRAETGDWFHIETAAYPEMHPQAKSPQDDLQNFVRKVKAGADSAITQYFYN
ADAYFRFVDDARAAGVEVPIVAGIMPITNYTQLTRFSDMCGAEIPRWIRLKLASYGDDTE
SIRAFGLDVVTRMCERLLAGGVPGLHFYTLNQAGPTTAIWQQLAR
>A0A538CJ99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MCRASSEGDEVPAQIQTRNRFLDRLETGPVIVGDGGMGALLSAAVPRLRTPEEANLRAPQ
AVVSLHVSFINAGAELIETNTFGANRRKLAHQFLDDDLEEINSAGVKLAREAREVTGRDV
FIGGSIGPLGEPTTSRVRRELFAEQAAVLDGRGADLFMIETFYDLEEVVDAIEAVRGVSS
LPIVALLTFDESAETLAGVTASEAADRLAELDVAAVGANHGAGLLAALAALERMGKNGKP
LAALPNVGLASLAGGRVIYPHATPEYFAEFAAHARDLGAKVIGGCCGTTPAEISAIRSAV
EEERKPRAPLVFESPELVVALGEEQRETGLSRALATGEWVVSVQLDPPLGGNSAGLVEVS
AALKESGHVGWVDINDNATARAGMSSLMVSATIERLAEIETIPHLTTRDWSVLGLESMLL
GAHAEGVRNILAITGDPPEVGDYPGARGVYEVDSIGLTQLMANLNRGEDFNGRPIDAPTS
FFPGVAVNPTADDVELELDRFRQKVEAGAKFAITQIVFDLDRFDDFTERLGGRWPIPVLI
EVFPLTSHRLALRLHNELPGIVVPDELQHALQDAGSDAAAIGFTHGSRERAAGVCLVAPF
RRRLRVLELLA
>A0A3N0X6B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epilithonimonas hominis|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFKPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEPSVGGHKYASDLVKQIHDLGIGEYLHGKIESDIDNSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKFFDFVKQAREIGIDVPIIPGIK
PIATKTHLQMLPQVFKIDLPEALINEVLKCKTNNDVREVGIEWAINQSKELLDFGIPVLH
FYSMGKSDNILKIGREVF
>A0A0F2IZ73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Magnetoovum chiemensis|TrEMBL
MVTAEIGPPKGTDISAMLHHMEILQGKVDAVNVTDNQSAVMRICSLAVCKLLLEHGIEPV
LQMTCRDRNRIALQSDLLGASILGIKNVLCMTGDHVTAGDQKGAKPVYDVESVQLLKIVD
MLNNGADMYGAELKGATNFYPGAVVTPEANPIEPQLMKFNKKVKIGAKFFQTQAVYNIDT
FKKFMEHARKYPVKILAGFVVLKSVGMAKFLNNFVPGIVVPEELIAEIKDAGKEKALDTG
LNIAARHIRQIKEENICDGVHIMAIGMEEKVPIILEKAGLL
>A0A376C9I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium amycolatum|TrEMBL
MSSTTPLSPGRQVTIRQALSMPSAGSIPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFA
SVTYGAGGSSRDRTLRIAQRVSKQPLTTLVHLTLVEHTVDELREILRSYLSAGLTNLLVL
RGDPPGDPLGPWVETEGGLHYASELIELIKAEPEFEKFEIGIASFPEGHYRSPDLDHDTQ
YTLAKLRAGAEYSITQMFFDIEHYLRLRDRLVEADPVHGAKPIIPGLMPITSLRSVRRQV
ELSGAQLPSDLEERLIKAADGDEQANKDEIRKIGIEFSTNMAERLIAEGVPGLHFMTMNF
ARASQEVLHNLGMAPAWGTGQDMLRGGF
>A0A3S3QB16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium cerinum|TrEMBL
MKVTEHIENANGKPLFSFEILPPLKGQNIQCIFDSIDPLMEFNPPFIDVTYHREEYEYKE
MPGGLLEKKIVKKRPGTVGICSAIQNKYQLDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VVALRGDAVKSEIYFKPEKEGNHNATELVTQIDNLNKGIYLDSDLQNTSATNFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGASYIITQMFFDNQKFFDFVAKCRKEGITVPIIPGLK
PISTKKQLNQIPHRFKVDLPDDLIMEVVKANDNEAVRQIGIEWCTAQSKELIKAGIPVLH
YYSMGKADNIKAIAREVF
>A0A0L8AD35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas geniculata N1|TrEMBL
MSAGMSLRADAFLNAFSLEVSAKAMPALRAEAARIPRGTIISIPWLASEDDDARLAAACA
VRELGFEPMPHLSARRIGSHAALERFLERTAGEAGVARCLLIAGDLATPIGPFADSASII
ETGLLERHGIKVAAIGGHPEGHPVMSSDERWQALQHKCQRIEARGMAPLIVTQFAFDADT
VLTWLDALRTRGITVPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVKGLTSAHGQVSPHLFPFGGVAPSLEWIEQYRQRVRGARGVIHED
>A0A133RZY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella atypica|TrEMBL
MMTLREKHQNGQFTITVELDPPKSSSAQKVFEQAARLKGKVDAINIADSPMSKMRMSPIS
LSYLLQHNEGIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDHGDHPFAQS
VFEVDCMGLLNIAKTLNSGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNG
AHFVQTQPIYDLEQAKRYIDKMSEFNVPIMLGLIPLKSFKMATYLHEKVPGINLTQDILD
RVEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A2G4GP01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAERFSTSERVFTVEFPSVDGGNLSAVKSRVDALLPWFDAANATDSPAAHAHASNVAIAI
ALQHFGLEPILQVVCRDKNRIAIQSDIMGAALHGVRNIELLTGDDVTAGDEPEARRVFDV
DGAQAIKIAVTLKGGRYLSGRKFSDAPDLFIGAVENAAAPPLEYRAERVTKKVNAGAKFF
QLQICFHGDRLENFTQAVNATHPSLPLLPTIVLLKGARPLKFMHEKVAGIDIPTEVIAKV
EQASDPKEAAYQLARAQAEHALSLPGVRGLHFTDFCHDDSLVRLMRDLGVAPRPTGSH
>A0A168PSA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor lusitanicus CBS 277.49|TrEMBL
MKIIDKIEQAQKSNHIAYSFEYFPPKTELGFANLIDRLGRMAQLEPEFISCTWGAGGSTH
DRTLELCTTAQSLYGLDTLMHLTCTNMEKAKIDEALEQAKKAGIRNILALRGDPPRGHEY
WTPVDSEFQHAIDLVKYIRKHYGDTFCIGVAGYPEGHIDCPDKEQDMQYLKEKVDAGADF
VMTQLFYDVDACVTWMQKCRAHGIQVPIVPGIMPIPTYQSFRRMINLCNVKVPDNVMSDL
DAIKGDDQKVKEYGVNLAVNMIQKLHKEAGICNFHISTLNLERSTRLILEALHLHKENGL
HVNKVSPWAPIHDPAKAELWDEFPNGRYGDSRSPAYGENTYSSGQILPTSQAILKWGEPE
TEQDIAQLFINYINGQVKSLPWCEEALHTESETIRQRLTDINQRGYWTVSSQPAVNGASS
QDKIYGWGPKNGYVYQKAFIEFFVSDQQVAELLTRIGKDDSITYYATNRKGDFSTNVSDA
EAQNAVTWGVFPGKEIIQPTIIEKASFEAWKDEAFSLWTEWEEQYAPSSSSQKILKEIGD
RYWLVNVVHNDFQKPDLLFDVMLS
>A0A553FKU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassomonas sp. M1454|TrEMBL
MNARARQLDLLNQTVRDLDQDLNVSFEFFPPNSPEMETTLWNSIERLAPLKPSFVSVTYG
AGSGTRDRTHGVIKRIQQDTGLIAAPHLTCIDAGREELIDIAKDYWESGVRHIVALRGDL
PNSGKKPDMYANDLVELLKGVADFDISVAAYPEAHPESKNAQFDLVNLKRKIDAGANRAI
TQFFFDMDSYLRFRDRCAAIGIDVEIVPGILPVSNFATLKRFSKLAGVNVPNWMGKMYEG
LDDDPTTRNLVGANIAMEQVKILRSEGVNDFHFYTLNRSELTYAICHTLGVRP
>A0A380P1Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weissella viridescens|TrEMBL
MEKTIKYSLEISTPATVGEQEDLIRQLQTLPRDEIEFIAITIGAGGSIELATPVLSFIQL
LLECINVPIVPHVTGSHQTQAQVQELLRKLSGMGIQTVLAVRGDGEPNAFGHGDDLIRFI
EKTGNLRCWEQLIRKDILKMIIYSKPFRRWKENGWRGPRP
>A0A537TUN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGSRFEERLASGQVVVGDGGMGVLVTSAVPRLRCPEEANLRSPESVVTLHTSFIRAGADL
IETNTFGANRRKLAQLYLDEELERINSAGVKLAREAREVAGREVFIAGSIGPLGDAQGLT
QEQRAEIFAEQASILDGRGVDLFMIETFYELDELEAAIEAARSVSSLPIVATLTFDEGAE
TLAGVSAAEAAKRLRPLELAAIGANHGSGLHAALAALEAMGSDGGPPLAALPNVGLASLS
GGRVIYPHATPDYFAEFAAHARDLGARLIGGCCGTTPLEIAAIRSAVEEERKPRGAFEAA
ERELVETALTGQPEETELARKLREGEWVTCVELDPPKGGRYDAMLAVASTLKASGKVGFV
DINDNPMARARANALMAAVAIERECGLETIPHVTPRDTSIMGLESLLLGVHAEGVRNVLS
VTGDPPEIGDYPGSRGIYEVDSIGLSQIVTQLNRGEDYNGKAIDAPTSFFLGVAVNPSAD
DLETEIGRLRQKVEAGARFAMTQALFDLDYLDRFEEQLGGWPLPVLVGIFYVRSYQLAVR
LHNEVPGIVVPEPVQRRLERAGPNAAAEGLALARELYAEAREKAAGVYLIPPFKQPEAAL
DVLE
>A0A2H0MGU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium CG11_big_fil_rev_8_21_14_0_20_56_8|TrEMBL
MKIRDILQHGNPVFSFEFFPPKNDEGFDQLFETIENLRKLNPGFVSVTYGAGGSTRSKTV
DLVGRIKNEIGIESMAHLTCVGHSADEIRSVLNELEKDGIENILALRGDPPQGETEFVRP
QNGFGHANELVGFIRKHYSFSLGVAGYPEGHLESRNLAQDMEHLKLKVDAGADFIITQLF
FDNEYFFDFVRRVREAGIQVPVIPGIMPILNVNQIKRFTKMCGATIPGSLVEKLEAVQED
HDAVRDIGIKHATEQCMDLLDLGAAGIHFYTLNRSRATLAILEQLTGRLLPDKNEL
>A0A538B8F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSLRFWKRRRASGLTEEQRAALKSLVADARYELIPLSSALESASALPPGSQVTVTASPSH
GIEATFDLAEAVAAQGHDVTPHLSAHMLRDRAHLARLLERARANGLRKVFVVGGDTRDRG
ELHDGLMLLRAMDELGHPFEEIGVPCYPEGHPDIPDERLLEVLREKQRYANAMTSQMSFN
PAAVTRWMGEVRDAGIILPLHLGVPGVADLPKLMRIAARIGVSDSARYLKKNKQLIGHLV
RGGSFGPDAFLERLAPMLADPVADVRVLHVFTFNQVEQTAAWQRRMLEELGG
>A0A849TGW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiaceae bacterium|TrEMBL
VTYGAGGSTRERTHTTVSRIVKETTLKPAAHLTCVGATREEVDAVVRDYWAAGVRHIVAL
RGDPAAGVGAKYAPHPGGYATTMDLIAGIKRIGNFDISVGGYPEMHPESGSLKLDIENLK
AKVDAGANRIITQFFFDNSHYLRFVERARAAGIWCPILPGIVPIHNFKQVASFASRTGAT
VPTWLARKFEGLEDDQGTQHLVAAAVAAEQVADLVDEGARQFHFYTLNRADLVFAICHLL
GLRAQPMEQKLAVNA
>A0A6S6T5W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Sulfurovum sp|TrEMBL
MFENFCKKLCSNETFISVEITPPHGASIKPTIEKIRELKLHEKVAGFSVTDNPLAKLKMS
GVLSAIQVQQAFNKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKYSDQPE
VKGVLERDSTLLLSIIYRLNKGLSYSNKELNPKPNPIYPFAVSNAHAKDMRRIKKSMLKK
LNYGARGIITQPVYNLENAKELLEIFEECKKESVRDTAKSAELILGQFPVVRAKTANFIS
DKVPGITVPKVIIEEMDLAAMDGAEKEQEVGYTISKEIFDGILKLHPKMHLMTHNRFDLC
SKLIGDIN
>A0A7S8WAY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQVKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWRSLWQVK
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVSLETRGTSSWKNWYLATEA
>A0A6H2BQ15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga oryzae|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIDSIYDHLDPLMDFKPAYINVTYHRSEHMFKKK
ADGAFEKVEIRKRPGTVGICAAIMNHYNVDAVPHLICGGFSREETENALIDLAFLGIDNV
LVLRGDAPKNETFFEPDPHGHAYASELLDQVVHMNNGVYLEDDLQGGVKTNFCIGVAGYP
EKHFEAPNMQTDMGYLKKKVEMGADYIVTQMFFDNQKFFDFVGKCREMGITVPIIPGLKP
LTSKKQMNILPRIFHVDLPTELSGEIMRCKTDKEVEQVGTEWLINQSRELKAFGVPVLHY
YTLGKPQVVRKAVEAII
>A0A6F8TEI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIDKVLHFSGK
ARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQTKSFLTKHDYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVKTGKEFTPEIARFSR
QPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENSVVAKALLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTNLDRCEFGDRECIHSVKARLAKAVKQT
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A7V9CIU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MQSQQEHARTFSFEFFPPQTPEGAEKLRTTRKQLAQLKPEFFSVTFGAGGSTRDRTLDTV
LEIQSEGQAAAPHLSCIGSTRASITEILRRYRDSGIRHIVALRGDLPSGTYSPGEFHYAN
ELVDFIRAQPGDNFRIEVACYPEFHPQSLSARDDLLNFKRKVDAGADAAITQYFFNADSY
YNFVDECEAMGITIPIVPGIMPINRYAQLARFSDACGADIPRWIRKKLESYADDTASIRA
FGLDVVTDLCDRLLASGAPGLHFYTMNQAGATSTIWQRLGL
>F7CI98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macaca mulatta|TrEMBL
MDHRKARVLPAGHYCPSLGIWASKAGSVRFSVPPSISRNLAMVNEARGNDSLNPCLEGSA
SSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDALELLNRPTQNEREMEAP
>A0A8C7HVR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus kisutch|TrEMBL
MVNQVQRVEDTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIR
NYGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVN
RRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEQT
AEQPNDEQSDKEQPGK
>A0A8C7K3C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus kisutch|TrEMBL
EHGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTESGDHWFSLEFFPPRTASGAV
NLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQT
KEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKHIRCEFDDYFDICV
AGYPTGHPEADSYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVRDCRAIGITCPILP
GIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIRNYGIEQTVGMCRVLLESGN
VPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSY
IYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEELTSEQSVYKV
FTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMMDELDKVNRRGVLTINSQPTINGKPSD
DPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPRVNYHIVNVHGQNTTNAHDM
QPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHD
NYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPDDIEALPGDGPVHQETWRRP
>A0A7K2Q4U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7760|TrEMBL
MALGTASTRTDRARTVRDLLASGSKSYSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSV
TYGAGGSTRGGTVKATQQIAADTTLTPVAHLTAVDQSVAELRHVIGQFADAGIRNMLALR
GDPPGDPMGPWVKHAEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVQKAGCETPIIPEVMPVVGIKQLDRLPQLSNAVF
PAAVKERMLAVKDDPAAVRSMGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQRA
>A0A6I3JBQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. zg-579|TrEMBL
MVTGPGRSLAEMIREGGKSFSFEFFPPKDEAGEQQLWDAIRALEPYRPTFVSVTYGAGGS
TRDSTVRITGRIARDTSLIPMAHLTCVGHTREELERILDSYREAGVHHVMALRGDPADGP
RAAWTPTEGGLTYATELVELVRSRGDFRVGVAAFPEGHPTAESLDHDADVLVAKARAGAE
FAVTQMFFRAADYFGLVERVRDRGVDMPILPGIMPILNLAAIRRQGELIGADVPQEIVSR
IAAHTGDPVRVRAEGIAVAAELCEELLAGGAPGLHFYTLNRSRATLEIFDRLNVSS
>A0A1V5M6Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium ADurb.Bin425|TrEMBL
MHPFLETLAKRPLLADGGIGTLLYSRGTSGEASFEHLNLTRQETVQQVHVDYINAGAEII
ETNSFSGNRFKLANHGLDAEVWKINVWSAKVARNAREITGQPVFVAGSVGPTGKLLPPLG
DTDRDSICDAFKEQMEALLAGGVDLFLIETMSSLEETALAVKAARNVSKLPVIAQLSFSV
EGHTLLGAVPEDIVKLLQELGDDMPDVIGINCGAGPGPVFDSFLRLTTAIKSLKIAPNRL
TFSCLPNAGQPSLMGGRPMFMSKPKYCASYIEPYLRAGARIVGGCCGTTPEHIKAMRQAL
DQYIAQNEEHSSKDESKETAETKGVGSLVTVLYNPEAIENTVETASQKENAKISLAERLR
RIKQKTEQDFYISVELDPPKGAGTKKITQAAELLYAAGADAINVGDSPMARVRMSSLATC
QLLSQRIGVDTIIHFTTRDRNLMGMQADLIGCQALGLHNILALTGDPPALGNYAHATAVY
DVDSIGLIKIIKQLNQGQDIAGNTIGAPLSLSIGCALNPTAQNRALELERIKRKIEAGAD
FIMTQPIYRKSDLADFIEDMGGCPVPLLVGIMPLHSSKHAEYLHNEVPGITIPKHIREEM
ARAGDDGARVGLEQAEALLAEVTELIEGTYLVPSFGRYDDMAALVTRLKRSRTIASSN
>A0A5M9I5B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mediterraneibacter catenae|TrEMBL
MDFHTIFRSRCLVADGALGTYYREKYGDTRRAPELDNLADPCKIETIHREYIKAGADILR
TNSFASNVRTLCPDRAGKMTRDERLKTVYDNVSAACRIAKTAVKQEQTAAAEEGRKLKEI
YIAGDIGPVPEQHSSDDQDEEIIEEYKEMVRAHLDAGINLIWFETFADFERILPVAEWIR
SIRHAFIMASFSVNAFGYTKTGLSMGELIKTAKESDLIDGIGFNCGVGPSHLSRLMKRQN
LGELIVAVSPNAGYADRIENRMIYRDNSGYFCEAMKEIAALGVNVIGGCCGTNPSYTRRL
ARTAENMPIAKRLADRPEQRAESEIRYDNNLFIRKLYSGEKVVIAELDPPFDGNDRKMME
AAGVLKRAGVEMITFSDSPMGKMRASAAMSAVKVSNQMQIETMPHMACRDRNTIGIGSEI
LGAYMNGIRNFLFVTGDPVPVGDRGSITSVYDHHSVTLMNYVRQMNRELFSEDPIAYGGA
LNYGRKNIDAEIRRMEKKCEAGASFFLTQPIYSDEDIERIRYIKSRIDTKIICGIMPLVS
YRNALFMKNEITGIHVPDEIIAQYTKDMSREEAQAAGVRIAAGIAGKLGEIADGFYFMVP
FNRAAMIAEIMEIMR
>I4S687|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 541-15|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A285TW09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira xiamenensis|TrEMBL
MTVKNDIAPQGTSHGDLRVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGST
RDRTHSSVTRIQGETGIPAAAHLTCVGHTKEEIEGIARNYWDEGIRSIVALRGDLPDAGD
KYVPTPGGYPYAVDLVEGLKRIADFDISVSAYPETHPDAPNADFEIEYLKHKIDAGANRA
ITQFFFDNEVFLRFRDKCAAAGITAPIVPGILPVTNFGSLLKFADMCGASVPKRLHWRFE
DLDEDPDTRRMVAFHEAISQVEGLMAEGVTDFHFYTLNRAELTYAICHALGIRGVAQAAA
>A0A2U8FL70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus porcitonsillarum|TrEMBL
MSFAANIDQLNQNIADLNGKINVSFEFFPPKNEKMETLLWDSIYRLAPLKPKFVSVTYGA
NSGERDRTHGIVKSIQQETGLIAAPHLTGIDATPDELKVIAKDYWDNGIRNIVALRGDEP
PGYTKKPFYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRAIS
QFFFDIDSYLRFRDRCVNVGIDVEIVPGILPVTNFKQLQKMAQLTNVKIPSWMHKMYEGL
DNDPTTRNLVAASIAMDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A1Y3RS08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor sp. An91|TrEMBL
MKIIDILNQDRPTLSFEVFPPKTSDTYDSVAKATQDIAALRPDFMSVTYGAGGGTSDYTV
GIAAGIQQQYGVDVLAHLTCASSTRDHVAQVLEHLKEKGIQNVLALRGDIPEGGAPAHDY
QYAAQLVRDIKAHGDFCIGGACYPEGHPESPTKNADIDHLKAKVEAGCQFLTTQMFFDNN
ILYNFLYRIREKGITVPVVAGIMPVTNGKQIARICKLSGTYLPERFKAIVDRFGDNPAAM
RQAGVAYAAEQIIDLIANGVEHIHIYSMNKPEIAASIQSSLSEVLK
>A0A2M7F9A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium CG17_big_fil_post_rev_8_21_14_2_50_50_9|TrEMBL
MGKKKTVRAAFEAGEFVVTGECGPPKGTDISEMLHHAEGMLGYVNGINVTDNQSSVMRIG
SLPVCKLLVDMGHDPVFQITGRDRNRLAIQSDLLGAHILGIRNVLCLTGDGVQAGDHKDA
KPVFDLESVQILQAVEALNNGKDMAGNDLKGATSLFPGAVVTPESRPIEPQLMKFEKKIR
AGAKFFQTQAVYDIENFLDFMKFARQFDTKIMAGLVLLTSAGMANYMNKFVPGVSVPQNL
IDRMKAAGKEKAIDTGIDIMCEFIKAVRDQCDGVHIMAIGKEHLVPEIVKRAGLA
>A0A257YHW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium 12-68-11|TrEMBL
MSYAAIHPDWEKPRTNMVDGYSLEMTAKELDGLREAAPLIRPGTQIAVTFLPGEDLEQRV
AAAVLVRELGFEPIVHLSARRIESLEQLDWYLGEITSKAQVKRVFIIAGDPPEPEGPFST
SLDVIETGLLEKHGITIVGVGGHPEGHPNNTPAELWDWMEKKLAAIRARGMVPLVVTQFA
FDDDAIVEWVGEMRRRNIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMMKYGISLTN
LIGSAGPDKLVNSLDKKLSDAEHGRVRLHFYPFGALTASAEWINQYAAKHA
>A0A4V1UQ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MSAPKVSFEFFPPKTPEMEQKLWDSVRRLESLNPPYVSVTYGAGGSTRERTHDIVRKMAA
ETSLKPAGHITCVAATKPEIDQVLQDYWDAGVKRIVALRGDPTAGIGTKYAPHPGGYAYA
NDLIEGARKIADFDISVGCYPEVHPDAASLKSEIENLKRKFDAGATRAITQFFFYPDVYF
KFLDAARDAGITQPIVPGIMLQSNFKGLKRMADLCGTAIPARIASLYEGLDNDAETRDLV
TAHVAAELCNRLAEQGVDHFHFYTMNRAGLSLSTCRLLGIKPEVQAKGVQA
>D6Z0B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurivibrio alkaliphilus (strain DSM 19089 / UNIQEM U267 / AHT2)|TrEMBL
MSANKPDFLEYIRERVLLADGALGSYLYAKGIELGKNIERLNLADPDLVYSVHEEYIRAG
SRLIETNTFGANRLKLENAGLEDKARQINLAGAELAVRAGSGEVYVAGSVGPSGADFPLG
ETEGPEREAVEAAFKEQIEALLEGGVDLLILETFSHLDELLLALKVARRLAGKMPIVANM
VYPKQGCTAAGLDALECGRAALAAGADVVGSNCGRGARAMLTAMERLAALGEEVPLAAFP
NAGFPEIVNHRLIYPAEPPYMAQLVREMVKTGARLVGGCCGTTPAHIQEFGKHLRLKRRP
LTQVASDKQATGPDSQAPTAAKAGSLLKRLPTDKLPVLVEVDPPTHLDISGVLGGAKELA
AAGADAITLGENPLAVLRADNISLAHKIRSEVGIATVAHVTCRDRNALGLQSQIMGAHLL
EIDSILAVTGDPATTGDQPAATGVFDVQSFGLIRMLNQFNQGRNPAGKAMKGQCDFSIGA
AFSYRPNNPDLQIRRLERKAALGAVYAMTQPFFSAGAVEDMLERTRHLEMLIFPGIFPLI
SARNAEFLHHEVPGINIPEDLRRKLGRYEAVEDQRRVADEFTRELIAEICPIIDGLYLIS
PLNKWEVTAELTREVRQAGWKGSGRLAALVQ
>A0A7T3EWC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria cinerea|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRVVALRGDEP
AGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A7L7LE09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adhaeribacter radiodurans|TrEMBL
MKVTEHIANAKKTLFSFEILPPVKGTSIQSIYNGIDPLMEFKPPFINVTYHREEYVFKER
ENGLLEKISIRKRPGTVGICSAIMHKYNVDAVPHIICGGFSKEETENALMDLNFLGIDNV
LVLRGDSIKTETQFRPHPDGHAYASELLKQVCNLNQGLYLDEDIANPVPTNFCAGVAGYP
EKHSEAPNLEIDLKFLKMKVDMGAQYIITQMFFDNQKYVNFVKACRENGINVPIIPGIKP
LTVKNQLRMLPNLFHIDIPNDLVQAIDKAQTPQAVRQVGIEWATQQCKELVQFGVPCLHF
YTMSKSEATAAIAKEIF
>V5TSU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula hispanica N601|TrEMBL
MALGTRAVSDSQGVRTLLTSARFELMPFESFDEEITHLPDNATIAITTSPQLGIEKTVEK
TEEAAEMGYDVVPHIAARYVEDQEQLEAIAERLEQAGITDIFVPGGDREEPAGEYESAHG
LLEALAETEYSFEEVGITGYPEGHDFIDDETLAESMAQKEPYATYIVTQLCYDPETVVEW
VEDIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDDEYNIRGVHIYTFNQTPDTEKWRHNRLDS
>A0A507CEL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synchytrium microbalum|TrEMBL
MTKITDKIAQKLKEDKCHWSFEYFPPKTEQGVLNLYDRLERMYKLGPEFIDVTWNAGGST
SDLTLDICTTSQSVYGLETCMHLTCTNMPREKVDIALKGAKDAGIQNILALRGDPPRGQE
HWEAVETGFAHASDLVGYIRQQYGDYFCIGVAGYPEGHLDNPSKDDDIKQLKLKVDCGAD
FIITQMFYDTNLYLAWLKDCRDIGITIPIIPGIMPIQSYGGFQRMTTLSKTIVPDFIKQG
LEPIKDDDAAVKDFGIQLSIQMCNELRAGGVRSFHFCTLNLEKSVRRILEGLEFYVDAEV
VKPLPWVPSLAKGRDKETVRPIFWANRTKSYIARTESWDDYPNGRWGDSRSPAYGDLDGY
GVSLKYSHDECREMWGAPQSTADIIKLFADYCRGQLKALPWSESPLAPESSRIRDNLTQM
NVMGYLTINSQPAVDGAPSADRSVGWGPKNGFCYQKAYLEFFVSPEALDILTARIATDPS
ITFYAVNRHGDLRTNTKGDGPNALTWGVFPGQEIVQPTVVEAVSFMAWKDEAFELWGRWS
NLYDPKSKSAQVITEIHDTWFLMNVVHNNYKVPEAVFDIFHLNVANGHP
>A0A1Y0CY90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanisphaera avium|TrEMBL
MGFTSARHVEALNQTMAELGTNINVSFEFFPPNSEKMEKTLWDSIERLSTLAPKFVSVTY
GANSGTRDRTHNVIKDIQEKTGLIAVPHLTCIDASRSELRDIAKDYWNSGIRSIVALRGD
LPEGLAKPDMYAEDLVRLLKEEADFDISVAAYPEVHPEAKSAQADLLSLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTVGIDTEIVPGILPVSNYQTLLKFAGFSNVRIPNWMHQRFQ
GLENDQNTRNLVGASIAMDQVRVLSQEGVKDFHFYTLNRSDLTYAICHSLGVRPQLSLPA
DK
>A0A424NIY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium TMED84|TrEMBL
MKVTEHFKQAKETLFSFEILPPLKGKSINSLYENLKPLMEFNPPFIDVTYHREEYIYKKQ
NNGLLERKAVRKRPGTVGICSAIMNKFQIDTVPHIICGGFNKEETENALIDLDFLGIDNV
LVLRGDPIKSETYFSPENDGHKYASDLINQVCSMNKGKYLDEDIKNTHSTNFCVGVAGYP
EKHFESPNMNSDIYFLKKKVELGAEYIVTQMFFDNQKYFDFVKLCRDNNINVPIVPGLKP
ISIKKHLNLLPHRFHLNLPETLVKNILKCKNNDDIRKVGVEWAINQTKELIDFGVPCVHY
YTMGNSSNIIDIVSKFN
>A0A085BLY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epilithonimonas lactis|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFNPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEQSKGGHKYASDLVKQIHDLGTGKYLHEEIVSDDNSSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKFFDFVKQAREIGIDVPIIPGIK
PIATKGHLQMLPQVFKIDLPENLISEVLKCKTNSDVREVGIEWAINQCKELLDFGIPVLH
FYSMGKSDNILKIGREVF
>D4DZ08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia odorifera DSM 4582|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLDAAPHLTCIDASPAQLRAIASDYWNSGIRHIVALRGD
LPPGSGKPEMYATDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAASIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPIAAA
>A0A4Q7PAE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cecembia calidifontis|TrEMBL
MKITEYIEQADKPLFSFEILPPLKGQSLKDLCEGIEPLMEFNPPFVDVTYHREEFIYKKH
PSGLLEKVATKKRPGTVGICAAIMNRFKVEAVPHLLCGGFTKEETENALIDLNFIGVQNI
LALRGDAPKSENKFVPEPNGHAYTKDLVKQIVNMNHGRYLHEETETGFHTDFCVGVAGYP
EKHFEAPSLKFDLKHLKEKIDAGAEYIVTQMFFDNQKYFDFVKKVREMGITVPIIPGIKP
ITTLGQITMLPRTFYLDLPDALMDELEKCKTNADVREVGVEWAIHQSKELIANGVPVLHY
YTMSKAEATYRIAKEVF
>R5SQR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:661|TrEMBL
MNVIELINSNQHTAFSFEVLPPLKGTGIERLYATIDTLREFDPKYINITTHRSEYVYQEL
GNGLYQRKRLRRRPGTVAVAAAIQNKYGLTTVPHLLCSGFTREDTEYVLLDLQFLGITDL
LVLRGDKAKHEARFVPEEGGYSHAIELEEQINRFNQGIFVDGSPMTVTRTPFSYGVACYP
EKHDEAPNLESDLMWLKRKVDAGAQYAVTQLFYDNRRYFDFVARARQAGITVPIIPGIKP
LKRTAQLSIIPKTFKVDIPQELAEEVERCTGDDEKVRQVGIEWCVAQCRELMEHGVPSLH
FYSVAAEDSIREVAKQIF
>A0A318HEL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium moriokaense|TrEMBL
MTFQSAATTVEELVTSANIEVIPLRGADEKALAIPAASTITITCSPKFGLERTLEHVIRA
RESGHRVVPHLAARMVEDEAQLRRFLGILSSVGVDDLYVIGGDGADPVGKYSEALHILEA
IQELDHDLQRIGVGCYPEGHPNIADDALVDALQRKQPYADYMVSQLCFDAGTFTGWLRTM
REAGISLPVRVGVAAPLQTRKLIELSLKIGVGSSVKFLTKQHGFVGNLLLGRSYTPEALI
SQIVNEAGFDELGIEGLHLFSFNQIDPTVEWQHRISAAATA
>A0A4Y6R586|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. NIBRBAC000502772|TrEMBL
MFPTRIEIIPSTGIVEQVQALVPLTTTLTMTCLPHHGIERTMRASVELSTLGYTVIPHLA
ARSIHDRAELTRIMRECDGAGIGEVFVIGGDRKQPAGPYESALPLLEDIAQYTGGRMRAG
VAGYPEGHPTVAALDLLDALQDKQHLATHVVTQMCFDAPKILDYAALLRREGVDLPVWAG
VAGSVPRTKLLALATQIGVGSSLKFLSSKGTLARKLLSGDRYSPHTLVAGLESQPGIAGI
HLYSFNNLDAVPNDAGLASSPTALQPALIRGAAREQ
>A0A212SEN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PgraA7|TrEMBL
MLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKATQE
IAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHPQGV
KYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVDKCRAGADYAITQMFFRPE
DYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDPAAV
RSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A626VB03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKISSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEIEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHT
>A0A2X3EZL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae|TrEMBL
MHPEAKSAQADLLNLKRKVEAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPV
SNFKQAKKFADMTNVRIPVWMSKMFEGLDNDAETRQLVGANIAMDMVKILSREGSRISTS
TP
>A0A139WXR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scytonema hofmannii PCC 7110|TrEMBL
MIQQSIEFGKDSQRRSFQTAVQTGEFLITAEVAPPKGGDPSHMVQMALALKNRVHAVNIT
DGSRAVLRLCPLAASVILLQHGIEPICQMACRDRNRIALQSDLMGANALGIHNILALTGD
PVKAGDHAEARSVFDVESVRLLQIIEKLNRGFDSNERPLTDSATQLFPGAAVDPQLPNWS
SLQRRFEHKIAAGAQFFQSQLIVDFNRLEKFMSQIAVNYGKPILAGIFLLKSAKNAQFIN
RCVPGVNIPQATIERLERASNPLLEGMIIAAEQIQLARQLCQGVHLMAVKREDLIPQILD
MAEILPLNQPVLAQPAVTTKV
>A0A7W7K124|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas kyeonggiensis|TrEMBL
MTILDPLAAPLFADVAGDIDVSFEFFPPKTEKMEETLWESIETLSPLGPRFVSVTYGAGG
TTRERTHNTVARIARETGIPAAAHLTCVEATKEEIDQVAQEYWAAGVRHIVALRGDPPRA
GEKYQTHPGGYENAADLVAGLRKLHPFEISVAAYPECHPDSPNPTADIENLKRKIDAGAN
RAITQFFFEPDTFFRFRDDAAKAGIDAEIVPGIMPVMSFASVVRMAAMCGTEVPGWMERL
FEGLDEHPGARQLVSATLAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGVRPKVPA
LVGA
>A0A7K5FLA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Probosciger aterrimus|TrEMBL
MVNETQHSCSASSSSKSDAGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTRDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPR
>A0A1C2Y046|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. TeCB1|TrEMBL
MKISELFKTGKPTLSFEYFPARTEKNAEILEKTLGVLAGLNPSFVSVTFGAGGSTREGSY
ELVKKLKQEKKLEVVAYLAAYGLRPDEVAAVLDAYQDLGIENILALRGDLGKDGAKEIPA
DTIHYAYELVTFAKKNYNFCIGVAGYPEGHLEAPSLEKDIEYLRYKVDQGADFVIANFFH
DNIYFYHLMERCQKSGITIPVIPGLMPVYSVKMMEMLAANCGATIPEQLKRGIAALPEGD
ADALVEFGIQYAAAQCEELLQEGACGLHFYTMDRSESTAGIVKILREKGLL
>A0A4U7JEM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminiclostridium herbifermentans|TrEMBL
MNFFEEKDYFLFDGAIGTYYSSKFNKNTACELANLFDRDSIYNIHKEYIEAGADAIKTNT
FGANRFSLACDQQEADKIIKMGWEIAKRAAEGTTTAVFADIGPIPVTEGFEVFEEYKRIV
DIFLECGAEKFLFETFASYDILLELSAYIRLKLPKAVIFTSFAVYPDGYTKEGLFYIDII
NKVSASGLVDAYGLNCISGPAHMLRLINDLNIEGRNIIIMPNSGYPSTERGRTVYIDNSE
YFAEKILDLKKFGVKILGGCCGTTPRHIAATTKLFSESTTCCENPNESGSSSERIAPKQN
ILFQLLESKKPILVEIDPPFDTKWEYMLKDTFLLKQAGADMITIADSPLAKARADSSILA
AKLYREAGIPTMPHITCRDKNLLGIKAMLLGLHIEGIRNVLTITGDSIAHTERENIKGVF
SINSSKLAGYISSLNSNVFYGEEFKIGGALNINAANFEAELKRAFTKIQNGIGYFLTQAV
YTDTGINNLIKAAKTLNVPIFAGIMPLVGYKNAQFINNEVPGIEIEQEIIEMFKDKSREE
SERIGINLSLNSINKLYNYVAGFYLMTPLRRTHVICELIKEIRNKSI
>A0A7K5FPV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Probosciger aterrimus|TrEMBL
MVNETQHSCSASSSSKSDAGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTRDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>M3ARN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudocercospora fijiensis (strain CIRAD86)|TrEMBL
MHISEKLAAAHAKGQHTCSFEYFPPKTAQGVQNLYDRMDMMHALGPAFIDITWGAGGRHS
SLTCEMVKVAQSAYGLETCMHLTCTDMERSKIDNALQEAYKAGCTNILALRGDPPREQEK
WEAKDGNFRYALDLIKYIKKTYGGHFDIGVAGYPEGVDDTTSADEHIKYLKEKVDAGGTF
IVTQMCYDADIFIDWVKKVRAAGIPESVPIIPGIMPISTYAAFLRRANWSKARIPPQWLE
VLEPIKNDDSAVRDAGCDLIVEFCRRLMDSGIMHLHFYTMNLAAAVRMVLEKLDLTPPAE
SPHPDIKPLPWRQSLGLNRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
GLDEYGIGLKGTNENNRKIWGEPKTIKDIVNLFVGYMRGKVESLPWSEAPINEEANTLVN
DLVALNSRGLLTINSQPAVDGVKSSHPVYGWGPRNGYVYQKQYLEVLVSPDLIGTVIRRM
EQDPDITYYAVNCNGELKTNAPTDGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYH
LGMEWSKCYEEGSESRKLIKEITQSWFLVNIVHNDFRQQQGIFPIFDGLKVSGLDEVAYT
NGVNGMNGFNGVSGHTHNHEKPATNGVPDGNNVVNGADKASSNSTLKH
>A0A1W9PU19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolinea sp. 4484_236|TrEMBL
MTSNENNNGYLVGTTLERMLKAGHFAVTGELGPPQSADGNVIREKAALLKGYVDGVNLTD
NQTAIVRISSIAAGAILIQEGLEPIIQMTCRDRNRLAIQADLLGAYALGIRNLLCLTGDH
QIFGNHPTAKHVFDMDSIQLVQMVTKMRDQKVFQCGEEFKGQEPRFLVGAASAPLADPLG
FRPYRLAKKIKAGANFIQTQLVYDIEAFAKFMEKIREMGLHEKTSILVGVGPLKSPGMAR
YMKNNVPGIDVPDEIIKRMSAAGKGEPWFGKKNADMTKEEKRARSKARQAEGIQVCIDLI
KQLREIEGVAGVHIMAIEWEKAVKPIVEGAGLYPRPSV
>J2FVE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. AP12|TrEMBL
MTAASRPAESPLFAGLPGDINVSFEFFPPKTEKMEEQLWDAITQLAPLDPSFVSVTYGAG
GSTRERTHSTVSRIVRETSLVPAAHLTCVAASKDEIAEVADQYWEAGVRHIVALRGDPPP
ADGGRFTPHPEGYASAAALVEGLKARHDFEISVAAYPEIHPEAISAEADLDNLKRKLDAG
ATRAITQFFFSTDAYFRFLDKALAAGITAPILPGIMPVTSFAAIRRMSGNTLVPDWLETM
FAGLDERPGPRALVAAVAAADLCKRLYEGGSRDFHFYTLNKAEQAYAICQLLGLRPKENA
A
>A0A1G8E1W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myroides phaeus|TrEMBL
MKVTEHIKNAKGKTQVSFEVLPPLKGQNIKGIFDSIEPLMEFNPPFIDVTYHREEYEYKD
AGNGLWEKRVVRKRPGTVGICSAIQNKFKVDAVPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKNETYFKAEPKGNKYASELVAQISDLNNGIYLDPELENTSKTDFCIGVAGY
PEKHMEAPNFDTDLKFLKQKIDNGAEYIVTQMFFDNTKFFEFVKRCREIGIDAPIIPGLK
PLATLNQLNLLPHRFKVDLPDELVAEVLKAKDNAAIRQIGIDWCIQQSKELIQAGLPIIH
YYSMGKADNIKKIIQSSL
>A0A2I1FZH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus irregularis|TrEMBL
MKITDKINNNLETSQPFYSFEYFPPKTDEGLNNLYDRLKRMSHLDPLFASFTWGAGGSTI
DRTTEMCATAQSLYGLESCMHLTCTNVVRGTIEKAMKEAKSAGIQNILALRGDPPRGQEY
WTSCDSDFTHAIDLVRFIRKEYGDYFCIGVAGYPEGNPDSENKEQYLKFLKEKVDAGADF
IITQLFYDVNTFVEWRDECRKNGINVPIIPGIMPIQGYNSFRRITNLCKIHIPAEILNVL
EPIKHDDQAVKDYGVTLAVSMISKLRNEHNTRGFHLCTMNLEKSVRLILEKLGFVQTEEE
RNLRRLSRRRSSAGFGPNDIIRQEPDGSLPTAKPVIWKERSVDYLGRPEDWDNFPNGRWG
DARSPAFGELDGYGVSLRIPPEQALGYWQRPTTLDDLKQVFKSYILGEIPALPWYEEPLY
AETEAIRSKLVHLNELGFLTVSSQPAVNGARSDDPIYGWGPRGGYVYQKAFVEFFVSPEN
FEELVEKIKGNPWVTYCASNRNGDFRSNTKDDSPSAVTWGVFPGKEIVQPTIIAKVSFNT
WKDEAYALWTEWEHLYPKDSPSQRLLKDIGDNWWLVNLVYHNYVNSEEIWEIFFKS
>A0A445N156|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MSTKTPSKLEKILSAGHLAVTSEVGPPRGSDAEAIKKKAEILRNHVDAINITDNQTSVTR
LCSLASCIHLKLMGIEPTLQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQSFGDQP
KGQNVFDLDSMQLIQTARYMRDEGKFLGGEEIKRPPKMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNLDKFEEWMRLARDRGLHEKCYIMAGVTPFKNAGMANYMKTRVPG
MDVPDEVVKRMKGVPKEKQAEEGIKICIETIQRLKECEGVRGFHIMAIEWEDKVPGIVEA
AGLYPRPKVE
>A0A3S7S880|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia persicina|TrEMBL
MSFFHANQREALNQSLAEISGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRNIARDYWDNGIRHIVALRGD
LPPGGGKPEMYGADLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRVPGWMTSMFE
GLDNDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGLAVA
>A0A7W7CTD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes abujensis|TrEMBL
MALGLPSRLPATPAIGDLVRGSAPTFSFEFFPPKTSKGEQLLWQAIRELEPLRPSFVSIT
YGAGGTTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGAGIRNVLAVRG
DPPGDPMGDWVQHPEGVLYAEDLVRLLKESGDFSVGVAAFPHKHPRSADIESDTANFVRK
CRAGADFAITQMFFDADEYLRLRDRVAATGCDTPILPGVMPVTRMATIERSSQLSGAPFP
PALLARFEAIADDEAAVRALGVELCAEMCARLIDEGVPGIHFITLNRSTATREVWQLLAP
MPTAA
>A0A6N7HN92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola sp|TrEMBL
MRNVDWLRDVRYEVIPTNTIEARVAESVPLEVTITVTASPTKGLGPTLDLAERLAERGYR
VVPHLSARLVVDERHLKEIVDRLTTAGIDDVFVPAGDADPPAGRYDGTLPLLAELTALGR
PFRHVGITGYPQSHPAIDDDIVVQAMWDKRAHATYIVSNLCFDAKALAAWVRRVRRRGVD
LPIRIGLAGPVERTKLLSMAGKIGVAESARFLGKHLSWFARLATSYSPGRLLARVAADLS
EPDLAVTGLHVFTFNQVAETERWRAELLRR
>A0A848X8Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MQVRSQDERPRRFQDPGAKPPLSFEMYPPRSAKGRRALAETTRRLAGVASAGFSVTMGAG
GSAPSGTHETALEIAQISGRPVMAHLIAQGHSRAETLRLADGFWQDGITQILALRGDPPS
ADQAVKKGGFSHASQLVAALRDRHDFRISVAAYPEKHPQARSLDDDIDHLKEKLDAGATD
AICQFVLDPAAYARFVDACGRRGVTAPLIPGLMPLENWPRVRAFAMANETRVPRRLDRLF
GAFEEESEARRLAAMAVVAEQARQLVAYGAPALHIYALNRWQMPLALAQVLQNADQAAAL
GLR
>A0A8F7GLV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. LW-XY12|TrEMBL
MSRTPSIVDRLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERLGPAFVSMTYGAGG
STRDRTVRVTGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGN
PLGEWEKHPEGLEYADELVRLVRELGDFHVGVASFPEGHHRSPDLDHDTRYLVQKLRAGA
EYSITQMFFDVEHYLRLRDRVVACDAEQGLKPIIPEIMPITSLRSARRSLELSGSHLPPV
LEERLRRAAGDGPEENRAAVREVGIEVATEMCERLISEGAPCLHFITLNFARATGEVLDR
LGYELEAPAAVQPA
>A0A6L5EP12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola sp|TrEMBL
MTNQPLPRGPRKRQNIAPLLAAPRYEVLPLPRVLEATEQLPAGSVVTVTSSPHKGVDATI
DVAERLAAQGMRAVPHLAARQLHDTAELSGVLDRLKLAGIDEVFVVGGDGQHPAGDFPDG
LALLRGMAELGRLPGEVGVPSYPEGHHAIDDATLWRSLHEKQEYATYTVTQLCFDADTIC
QFAATAQREGITLPIVAGAPGVVDMTKLLRVGLRIGVGDSLRFTRGNRSVAGKLLRPGGY
RPDGLVRKLAGRVADGDCALSGLHFYTFNHVAATARWVRQTHRRAA
>A0A559VJN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. BK340|TrEMBL
MRDILAAGKKTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSVTYGAGGSTRTTTVKE
TQQIVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWVPHP
SGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSVDWDTDVAHFVDKCRAGADYAITQMFF
QPESYLRLRDRVEAAGCDTPVIPEVLPVTSVKMLERLPKLSTAQFPDALKERILTAKDDP
AAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>F8EV45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymomonas mobilis subsp. pomaceae (strain ATCC 29192 / DSM 22645 / JCM 10191 / CCUG 17912 / NBRC 13757 / NCIMB 11200 / NRRL B-4491 / Barker I)|TrEMBL
MDRILKENPNFADVAFLGDKTTNISFEFFPPKNEQSDKMLWQSVERLAPLNPRFMSVTYG
AGGTTRERTHATVTRIARETSIPAVAHLTCVNASREEIDEIAQDYWNAGIRHIVALRGDP
PGGGRFEARPDGYASAVELVEGLKKIAPFEISVACYPETHPQALSPQADIDFLKRKFDAG
ATRAISQFFLSPEVFLRFRDRVAAAGITAEILPGIMPTSNISGLKRMAHSCGIEIPERLN
QLMDSLDKDDAAIKQMVSMAVVTDLCGRLAKEGVDSFHFYTMNRADITSALCRLLGRQPA
>W6K754|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospira sp. (strain QH-2)|TrEMBL
MTESRSPSRRPATLAVASPLPRDVRVSFEFFPPKSDKMEATLWASMTRLAPLAPSFVSVT
YGAGGSTRERTHATVTRILRETDIAPAAHLTCVGATRDEINDIAGQYWDDGVRHIVALRG
DPPEGESTYRPHPGGYAYASDLVAGLRKVHDFELSVAAYPETHPEASSPDADLNNLKAKV
DAGATRAITQAFFDPEVFLRFRDRCDAAGITVPIVPGILPVSNFVQVKKFSAMCGTSVPS
WMGDLFGGLEEDPETRKLVAATLAAEQCRVLSAEGVKDFHFYTLNRADLTYAICHVLGVR
PQG
>A0A364JXD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falsochrobactrum ovis|TrEMBL
MGFNGLSRRPDVGKTTRVSFEFFPPKTEEMEQRLWETVTRLAPLKPEFVSVTYGAGGSTR
ERTIRTVARILKETDIQAAAHLTCVDATREEVDVVAREFADLGVNHFVALRGDPASGPGS
QYVPTPGGYQNGADLVGGLRKIGAFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGMLPVHNFKQVRNFCARSATHIPSWLAERFE
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMLGIRPGITQAA
>A0A1Z3HQ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomicronema hongdechloris C2206|TrEMBL
MNRFLAAAQSGQFLVTAEVMPPKGSNPDRMLMVARQLKSWVHAVNITDGSRAVLRTSSVA
SAAILKQADIEPICQMTCRDRNSIALQADLMGAHMLGIRNVLALTGDPIQAGDHPKARKV
FELESVRLLRLIDRLNQGCDRNGNPLKDEATQLFPGAAVDPQSPSWSGLQRRFQRKLEAG
AQFFQSQLICDFDRLEKFIDQIASQSDKPILAGIFLLKSAKNARFINKYVPGVEIPQHTI
DRLERASHPLQEGITIAAEQVNLARQLCQGVHMMAVRREELIPQILEQAGISPLSPEVSP
HVAQEEAVKV
>A0A2U1T546|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium yudongzhengii|TrEMBL
MPTRRQAAPRLSASAPVDSGEQASSSTPHWDRLALSFEVIPPRAGNTADVEKLDGLLAEL
ESYRPDYLAVTSSQRSGWLKGTTALIEYITETTRMRPLAHIACTTGDRAAMVRGINELID
AGVRGLLALRGDLPEGESSLPPGYLQHATDLIRLIRDVERGQAARFAAGNLAVGVACYPS
GHFESANEDEDFDVLLAKQRLGADFAITQLFFEAEDYLRFVKKARLAGVTIPLIPGIMPM
TSAKRLERMGKLAGLSVPEKLAKQLNEAALIGPDAEWETGLELTVQLAREVLEGGAGGLH
VYTHNKIDVTRELLTRVGIHPKQPMRRMA
>A0A2D5TFZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTRHFDLSFEFFPPKSLDASFRFWHAVETLQVFSPNFMSITYGAGGSARDLTCSAVRVIT
ENYDVPVAGHLTCVDATMAETLSVATGYAASGVRRIVALRGDGTGPGGEFVPVRNGFSGS
LDLIRALKEIDSFDVTVAAYPNRHPDALSDSADVDHLKAKFDAGADRAITQFFFEKEDFL
RFRDRCTSAGISQPIIPGIMPIENWAKTKKFAQASAIPIPAWLEEGFRHAKAGGTERLFS
TALCAESCDDLLYEGVDGLHFYTLNDPTLTSDVCRALGRTQRHLELKATA
>A0A2S1LN29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium kingsejongi|TrEMBL
MKVTEHIENANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFQPPFIDVTYHREEYEYKE
LPSGLLEKKIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VVALRGDAVKNETYFKPEKEGNHYASELVSQITSLNQGIYLDDELQNSSATNFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGASYIITQMFFDNKKFFDFVAKCRKEGITVPIIPGLK
PIATKKQLNLVPHRFKVDIPDELIMAVVRAADSEAVKQIGIEWCIQQSKELLQAGIPVLH
YYSMGKAENIKAIAKAVF
>A0A292E9E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. ACO-34A|TrEMBL
MARNDHNEQAGAPLRISFEFFPPKSEEMEGQLWATVDELSRWNPDFVSVTYGAGGTTRAP
TLSTVRRLISETTLPTASHLTCVGATKDKVRHVVDEFRAVGVRHFVALRGDPQGGMGTAY
QPYPGGFANAAELVAGLREMGDFEISVSAYPEKHPESRDEAADIDMLKRKVDAGAHRALT
QFFFDNDIFERYLERVRAAGITIPIVPGIMPIQNLTQLKRFASMCGASVPSFLDDRFAGL
DDQPQARAEVAAEVAAEQIEDLVRRGIGDFHLYTMNRAPLVNATLANVGLKPSVQAVAGA
AA
>A0A543ECU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium aquifrigidense|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTHGGHASAMDLVNQINDLGRGKYLHNEEQVSDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWSIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A0P8A480|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium HLUCCA08|TrEMBL
MSLLPFRKKPQTGGTPPTDPRIGRFIEGFSIEVMPRTAEKVEDFKAILPAGTRVYIAHIE
GTPIEDMVATARRLAGDGFQVMPHFPARIIRDRAMLADWIARYRGEAGVSQALLLGGGVA
RPQGDYDNSMQLLESGLFADFSRLHVAGHPEGNRDIDPAGGRANVDAALRWKQAFSDSTD
AEMAIVTQFAFAAGPIIDWADSLRAAGITLPIHIGIAGPAKLQTMIKFAMACGVGPSMKV
LQKRAKDVTKLLLPFEPTEVLTDLAAHAATDPDFNVTHVHFFPLGGIRTCADWAATHGAA
PAVAQA
>A0A3B8QUJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTALSFETFPPKSLDAAFHLWDTVQVLNPLNPRFISVTYGAGGSTQALTQEAAQTLRKTS
GLPVAAHLTCTGQSKGQVLETANRFAKSGITEILALRGDPAGGNTFKSHPDGYANSIELV
KALADLGKFNIRVGAYPESHPDAASMDQNIDWLKAKIDAGASEAITQFFFEADNFLRFRD
ACANAGIDAPITPGILPISNWKRAKVFAEQCGTPIKVVTATAFDRAERENRSDLFALTFC
SDLCDTLMSEGVSALHFYTLNRPDLTLKVCRALGLVPVANIRNVA
>A0A1C3H4Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cardiobacterium hominis|TrEMBL
MCKIPLSCEFFPTATPEGAEKLAAVRRELAYLQCEYYSVTYGAGGSTRDRTMNLVARLVA
ENGPPVMPHLTCVASSEADIRSLLDDYRALGIYRLMALRGDMPSGALENAGFTTAQQLVA
YVRELWGNNARIFVAAYPEVHPRAHTPAADLQAFRDKVAAGATDAVTQYFYNVEAFLRFR
DEALALGIDVPIVPGIMPISNFNQLSRFSDACGAEIPRWLRKRLEALQDDLPALCDYGAD
VVAGICERLIAEGVPALHFYSMNRADLIGELCKRLGWC
>A0A0A8F2G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis LNP21362|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A2D5J9F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MIAETDPRGRLERVLRSGRFAITAELNPPDSADPEDVYDAARPLGEIADAVNATDASGAN
CHMSSLGISALLVRAGWEPVLQISCRDRNRIAIQGDVLGASALGVHNVLCLTGDDVSAGD
QPGAKPVFDLDSVSLLRTLRTMRDDGLFLSGRRITRPPRLFLGAAENPCVDPLDWRADRM
AKKIDAGAQFIQTNLIFDMPRFERFMDRVRDLGLHRRAYILAGIGLLPSARTARWMRARV
PGIHIPDEVIARIEAADDQAEEGKRICIELIRHVRDMPGVSGVHVMAYRREHQVSEIVLR
SGILERRRIMGHQVATQKGSGGAGAAKTLE
>A0A7T1H0Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia sp. 2.29|TrEMBL
METALSFEISAMSKIDNTLEHLLKNTEELTPLFYTVNTEIGKTEWRDTYNTCCELKNLTH
VNVVPHIAINNKDECELCFIIEEYLKNDITELFVIRGDRHRFDEELPFNYGIELIDFIRR
RYPEVMIKSSIYPDYHKESITPEIEIDWLRKKLQLGVTELISQLCLNKNAFSYMKKQLGN
DIPITISMMPMLNFSFIESFFKNNAIDYPLWIKKHIRPSNINNHRAFGIQLTQFLIGEYI
KENKRLHFFTLNNAEMVKKLFDKLR
>A0A840Z4A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas endophytica|TrEMBL
MTFSVNQLEEARRALEAPLYADVGGDVEVSFEFSPPKTDKAEENLWQSIETLCPLNPRFL
SVTYGAGGSTRDRTHATVARIARETKVPAAAHLTCVEATRAEIDAVAQEYWAAGVRHIVA
LRGDPPAGAADYAPHPGGYENAAALVEGLRRLHPFEISVAAYPEMHPNSADLAADLDNLK
RKLDAGANRAITQFFFEPETFFRYRDAAAAAGINAEIVPGIMPIGSFAGVTRMATMCNTD
VPGWLVRLFEGLDDHPAARQLVAATVAAELCRKLYAGGVKQLHFYTMNKAELSFAICHLL
GVRTRPAQERAAA
>A0A083XWI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum EK13|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A1Q4W581|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02923|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVRHPEGVMYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYFRLRDRVAAAGCETPVIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEESPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A1B2ISH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILNRYQNSKEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNHADIAERIWNTTKSVFDAANARTRTTIKHRS
>A0A4R2QML6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tamaricihabitans halophyticus|TrEMBL
MHKIVDRLAEARRPAFSIEFFPPRDAADEQRLWHAIRQLETMDPLFASVTYGAGGSSRER
TIRTTGRVAQETTLVPMAHLTAVSHSVAELRHVIGWYAAVGVRNILAVRGDPPGDPMGEW
IAHPEGLTYADELVRLCKELGDFCVGVSAFPYGHPRSDSLATDTEYLVRKIDAGADFAIA
QLFFHPDDFLRLRERVAARGCTVPILPGVMPLTTPKTLRKAVELSGVPETPAVVRELEPY
MDDPASFRAAGMDFVHKLSADLLGEGVDALHFYTMNRSTATGQLVDSLGLSPALV
>A0A1L3LNV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium americanum|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMEIQLFQTVADLSVFAPAFQTVTYGAGGSTKAR
SLTTVKRMIGEMGLENTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGSA
YEPFPGGYESSAALVKALRARGDFEISVSAYPEKHPESADVAADIDMLKRKVDSGATRAL
TQFFFNNDDFERYIERVRRAGVQIPVVPGILPINNLTQVIRFAGLCGSKVPEAIISRLAH
LDDQPEERFKEASHIAAEQVVDLARRGFRDFHLYTMNRSPLIAAVCDLVGYQRRPARPTA
APSYPAVATA
>A0A2M9TAI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. 141|TrEMBL
MGSQEHPLGISFEFFPPNTDAGREKLIHVRDELVACNPRFFSVTYGAGGSTQARTRDIVR
TVSESGITTAPHLSCIGSEKAQLRDLLAQYQSEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPSLDKDVENFARKMNAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAF
GTEVVTRLCERLLDGGAPGLHFYTLNQAAPVMKIVDNLT
>A0A087B343|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium catenulatum subsp. kashiwanohense JCM 15439 = DSM 21854|TrEMBL
MHSPMFSLEVFPPKRTSPVGTICDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVS
EYGIPSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFEHASDLAA
YIRQQRPGMKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KARTAGIDVPIEAGIMPVMNAKSVLNMSSKCQSKIPEKLGIMLDKWGSDKALLKEAGIAY
ASEQICDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A4V3HEY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicyclobacillus sacchari|TrEMBL
MPSGGWETWSIPPRELAAAASRYVIFDGAMATYLHQCGVPIRVCAEELNLSKPMLVEQVH
RAYVEAGATVVQTNTFAANRLDLARYGLDAETAAINHQAVITARVAAAQRASVYGTMGPA
AGGTRYGALLTADERSRLGQVYEEQAQALIAAGIDGIVLETFPDLEELLLALRVVRSIAP
DLPIVANLSPEEVGVTRDGVLLTQAFATLRDAGASVVGLNCRLGPYGILRSFEQIAFDGG
PYAAVPNGGILHRSESEGLAYTGDVDDFARVMSDIARLGVRWLGGCCGTTPEHIRKLVLT
LQAQDAIGTPAEPDQNPLPVQVVVADERAEVDHVAVEVPLGPSIVDMLANRNRTTVIVEL
DPPKHLSATRFLAGAKALCEAGADMITMADNSLGSVRISNMALASVLKQRGIEPLVHVTC
RDRNLIGQQSHLMGLHVLGVRNILLITGDPSRYGDLPGATSVYDVSSMDLTKMVRKLNDG
VGFSGKPLQRPAQFVIGTAFNPHVHNFAKAVDRLRRKVEAGADFVMTQPVYDPALMERIA
DVTQDLGVPILIGIMPLTSARNAEFIHHQVPGISIPADILSRMREAAPEEAQEVGVEIAK
SLVDRALSCYRGIYLVTPFLKYDITARLTAYIRELTVPAVASAARGGL
>A0A842K932|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 4CII|TrEMBL
MTNLSNETGVRRRSSNAADLVRNMSYEVMPFKNTEQDVVDHVPTTVPLTVTVTEAKGIDT
TLNLTEKLIGHGYQVSPHLPGRQFVDDAHVADVIARLSEIGVKSVFVIGGDAPDPAGKFV
DAFGLLRAMEEVGHPFQEVGIGGYPEGHGAIEQELIDLALQQKAPLATRVLTQICFDATT
TSKWAAGVAASGVDRPIYVGMPGPVSRQKLMRISAGIGLGQSARFLQKQQSMLWRFLLPG
GYNPTRLLKQLGSAVPKTSNNIAGLHIFTFNELRKTEIWRQKLLTAIVEKDARS
>A0A2P5K607|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|ANME-2 cluster archaeon HR1|TrEMBL
MGLEEAIRSGKFIVTAEICPPKGTDISGLFSEAALLQGIVDAVNVTDCPRAMVRMSPLVL
SSELIKMNIDTIMHLTCRDRNRIAIQSDLLAAHALGIRNVLAMSGDFTTMGDHPYAKPVF
DLDSVQMLQVITKMNRGFDLMDNPLGGATSLYAGAVVNPGARPLGFVRIKLQKKISAGAR
FIQTQAVFDADLFNEFMDEFKSLNIPVIAGIIPLRSAKSAGFMIENIPGVKIPQAAINRM
ESASDPVTEGLKIAAETIDRIKENCQGVHIMPIGNHDHTKRLLEMCSLL
>A0A7Y3ZV16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. RE88|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDASREELARIADDYWANGIQSIVALRGD
IPPGGGKPEMYASDLVKLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQV
>E6VR83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio aespoeensis (strain ATCC 700646 / DSM 10631 / Aspo-2)|TrEMBL
MRIPDLIGSLSRPFVSIELLPPRREAELAGFGQAVQALKGMKPLFAAVTCGAGGRGAVGT
LETARDLAEDHGFTVMPHLTCVHVPPAALPGQLDALRTCGIRNVLAVRGDFPAGMEPVSK
GFRHASDLVARVRQLAPDMAVGVAAYPDGHPDSRSILEDIGFLRFKLDQGASFAVTQLFF
DNRRYFDMVDRLAAMGCTKPIIPSILPIRSLGQIKRVMELCDAPVPGTLLADIEAAHAKD
GDAGVRRYGVAQAASQLSELLEQGAPGVHLYPFNRADMCLEVVQRAGLLP
>A0A7U8SPD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus WBG10049|TrEMBL
MRQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A0Q4WKF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. Leaf91|TrEMBL
MPTASHHRASRDGYRPIQVSIEFFPPKTDEMEKVLWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMIKETSLKPAAHLTCVDATREEIDEVVQSYWDAGVRHIVALRGDPQDGVG
TAYRPHPGGYARTSDLVAGIKRIGDFKVSVSAYPEKHPEAATLDADIDALKAKVDAGADQ
AITQFFFENDVYLRYVEKVRAAGIEIPIIPGILPVQNFKQSANFARRTGASVPYWLAARF
EGLDNDVDTRRLIAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKV
AAAKAA
>A0A4R8YPE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium breve|TrEMBL
MPTTSDPACGNIPFSFELYPPQSDAATSALHATILRLAAAGPDFISVTYGANGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSNAEASQLIREFLDAGVRSFLALRGDPPEGAREGEAF
LGDLGSAAELVQLIHRVQAEREPYRESVIPGLPAARSITRERNKVRIAVAAFPNGHPRSR
STAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRQATALARELIAGDAPGLHLYAFNQHE
TVLSVLDGCGLLTPTSSASAPSASAPPASDPAKEYS
>X6CUH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNHC232B00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKSDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILQETSLTPAAHMTCVDAARHEVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHADGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A2T5LSZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus ochraceoroseus IBT 24754|TrEMBL
MHIKEKLAQNEAAGRIGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPRERVDAALQSAYKAGCTNILALRGDPPREKEV
WEAADGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSSF
VVTQMFYDTDHFINWVKKCRDRGINVPIIPGIMPIQTYAAFIRRANWTKARIPPDWLEAL
EPVKNDDAAVKEIGKRLIADMCRRLIAAGINHLHFYTMNLAQATQLVLDDLKLTPTPETP
LQRALPWRPSLGLNRREEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDA
YGIGIKGTNDQNIKLWGEPKSLRDLADIFVRFMEGKLERLPWSESPISAEATSIKENLVE
LNKRGLLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLLPPYLINDLIARIEANE
DLTYHAVSKSGELLTNTRDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYQLGEDWA
KCHDAASPSRKLIQGVMDNWYLVNIVNNDFHNTYNLFELFNDLNVKDLDVEVAGEIVEPK
ALQNGTTNGTTNGATPEPVAQN
>A0A4S0J2P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.191.01.1.1|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLAQLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHLSCIGSSKESLRAILNQYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCQRLIDAKAPGLHFYTLNGAAATKAICERLKG
>A0A7C1FCV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ammonifex degensii|TrEMBL
MAVSKFQEALNSGKFVVTCEIGPPKGTNLSKMLHHIDLLKHRVDALNVTDHQSSVMRFPS
LGGCLSVKERGGEPILQMTCRDRNRLALQADLFFAYSRGVRNVLCLTGDAVVIGDHKEAK
GVFDLDSVQLLRAVRQLEAGEDLGGNKLDGAVEFCAGAVVCPEADPIEPQLIKFEKKVEA
GAEFFQTQGVYDLEKFAKFMEFARQFPVKILAGIILLTSAGMAKYMNANVPGIRVPQHLI
DELARAGKEGALRKGIEIAGRMVATIKKEKLCDGVHIMAIGREELVLDILEAAGI
>A0A5J4PGW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
EILKCKNDDEARQAGIEWCTAQCKELIARKVPSIHFYSIAAADSIKEVARRIY
>A0A6L3JZG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides cellulosilyticus|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYDTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNRYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELTCEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A7J5ZE67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dissostichus mawsoni|TrEMBL
MVNQVQRGDGSWQSCKSDSSGASNSGGESSKESSRCSTPVLDADRLDRLRDKMRKRTESG
DCWFSLEFFPPRTASGAVNLISRFDRMGTGGPLFIDITWHPAGDPGSDKETSSLMIASTA
VNYCGLESVLHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNHAI
DLVQHIRSEFEDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAIEEITEVIEPIKDNDAAIRNYGIQQAVEMCRVLLDSGKVPGLHFYTLNREV
ATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNG
RWGNSSSPAFGELNDYYLFYLKSKSSKDALQQMWGEELKNEESVYEVFTCYITAQENQSG
HKVKCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTDPVAGWGPAGGYV
FQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWGIFPGR
EIVQPTVVDPVSFMFWKDEAFALWIEQWANLYEEESPSRMIIKYIHDNYFLVNLVDNDFP
LESCLWQVIDDMFELLDAPPETHHDGEVSE
>R5S317|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:545|TrEMBL
MKISEILTGSKHTFPSIEIVPPLNGMSKTELLDKVRTFMEFSPKYINITCHRDEYAFRRE
SDGTYTRHLVRNRISEVAVCAAIQAEFDIDAVPHVICGGTSAEEIESDLYNYRFLGISNL
MALRGDSVSGEKRFTPHPSGYSHANELVEAIRRFDAQSEESFCIGVGGYPEKHFECANIE
TDILNLKRKVDAGADYIITQMFFDNSVFYSYVEKCRKAGINVPIIPGLKPLSSPKQIALL
PQSFSLDIPKELTDAVRDAGDDKEEVYRIGTEWCIKQCKDLIKNEVPAVHFYTMGKTRNI
TQIMRECF
>A0A1X0V628|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc mesenteroides subsp. mesenteroides|TrEMBL
MTRITDIYKKKSAPVLSFEIFPPKTEDGLHALYKTLQEVNPKETGVDYISVTYGAGGGSN
HKRTKEIAEYIERNCGITALHNLTGINQTPSSLKGNLEKISVAGVENIFALRGDTPTKDY
VNEYYPFAKDLIKEIKKDGRFDIGAAIYPEGHVDNPTTGISVTGVKEKVISGTEFLISQL
FFDNGVFYNMQEALKENYIKVPVSAGILPIISRAQVERITYMIGSSLPARLAKIVHKYED
QPEALQQAGIEYALEQIHDLLDHGVDGIHLYAMNQPNVLKIMLPEINRHIQSKILTL
>A0A2D8P3L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritimibacter sp|TrEMBL
MSLFFSDPNAIRPYEPIPEGHKSGSVLERVLRAGEFAVTSELNPPDSADPEDVFAAAKPL
SEVTDAINATDASGANCHMSSLGICSLLTRTGHGSVYQISCRDRNRIAIQGDVLGAAAMG
VRNVLCLTGDDVGAGDQPGAKPVFDLDSVSLIRMIRTMRDEGRFLSGREIVKPPRLFIGA
AENPCVDPVDFRAERLAKKVDAGADFIQTNYIFDIPRFERFMERVRDRGLDKRVFLLAGV
GPLASAKAARWMRSNVPGLHIPDAVIDRLEKADKPGEEGRRICVELIQQVKEIAGVSGVH
IMAYRREHLVADILREAGIARPQKEIA
>K4IQT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium asteroides (strain PRL2011)|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLMPDFISVTYGTGRRSDRTATARIAKTIH
TEYGIPAVAHLTAQYADREVIDQALDMFDDAGVAAVLALRGDSVEGREPAGVFEHASDLA
AYIRSRRPNLSIYGACYPETHPEAASPEEDIENLRIKVDSGVDHLVSQLFYDNADFLDFL
DRARAAGIQVPIEAGIMPITNEGQVRHMSEVCKARIPAAVESILERWGDDRASLREAGII
YASQQIADLVAHGVDGIHLYSMNHSGVTRRIWHNVRHLFRQVGANSESSSDKS
>A0A3D5YXC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prolixibacteraceae bacterium|TrEMBL
MKVIDIINQSNKTVFSFELLPPLKGNDASKIYKTIETLVDFDPKYINITTHRDEMMYIEL
PDGRIEKRTVRKRPGTVAIAASIQHKYGIPVIPHILCGGFSKSETEHVLIDLNFMGIKNV
LALRGDGNKGEHVFRSDPNGHSNANQLVEQIVNLRNGKYLEADLKNTHPMDFCIGVAGYP
EKHFEAPNAETDLQYLKQKVDAGADYIVTQMFFDNQKYYDFVTKCRAIGINVPIIPGIKP
INLKNQLTVLPKLFSIDIPQELATELGKCKNDDDAKVVGTEWAIQQSKDLVANKVPSLHI
YTYGVSDNTRKIVEAVF
>A0A1Y3UCQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enorma massiliensis|TrEMBL
MHVDDIFTKAHAAGKIPVSFEMFPPKGELTLDKAHDAAKKLSAYGPDFISVTCSAGGGGN
FTQTAAIASMLESEFNVSSVAHLTCISLTQEGLKERIAQYKAAGVENVLALRGDRPTKDS
PLYGAPSDFSFAAQIIPALIEAGFCVGGAAYPEGHIECESLETSIEHLKLKQDAGASFFV
TQLFFDNEYCYRFLDLAEKSGITVPITCGIMPFVSKQQITRMVLMCGASLPSPVIKLLAK
YDDDPASLAQAGIDYACRQLQDLKEHGVDGLHVYTMNRPSVASAAMQALGR
>A0A093RA98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pygoscelis adeliae|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADSFLKFMKDCQAIGIT
CPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCREL
LDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRVEDVRPIFWAS
RPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEE
SVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNIN
GKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQNIT
NAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMII
QYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A8J7M4U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermohalobaculum xanthum|TrEMBL
MNINRPKARVSFEFFPPKTPRAAVQLWESVERLAPLSPKFVSVTYGAGGTTRDRTLAAIL
AIRERARLEVAGHITCVGATKEDVLKVARGYAKLGCRRIVALRGDPPAGAGKFEPHPKGF
SGSVELVEALADMAQFEIWVGAYPEKHPEAADMRADIDHLKRKIDAGATGAITQFFFENE
TFYRFRDACAASGINAPILPGVLPIDDFEKTAGFAARCGTDVPDWMHRAYRNAETEDEHD
LLSVAIAVEQCDDLLANGVEHLHLYTLNKPELPWQVCRALGIEPHPLRMAASCG
>A0A8H5PK00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium pseudocircinatum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLSSDSSGHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSSIKDGYWLVNVIHHD
FVERDALWQLLLS
>A0A0Q9LD75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Soil724D2|TrEMBL
MKLDLRTALQRDILVGDGAMGTYLYQMGFPVGISYEELNLLRPETVADVHRRYFEAGARL
IETNTFSANREKLSKYGLEGDVEAINRAGVELARKAVGDEAYVVGAIGSIRAGKRKNVRT
TDVEESLREQIGILLDSPVDGLLLETFYDLEELQLALRIIRSMSELPVICQFANEGTGST
QDGIPLQEAFQRLRNDGADVIGFNCRVGPNGILRSMEKLTPIAGIPFSAFPNAGLPDYVD
GHYTYAATPQYFAESALRFADLGARIIGGCCGTTPEHIAAVAKALHGYVPAAPGTMPSAR
AVRVSEPAPAKPAPPAGKPSLLEIVKQRKTVIVELDPPRDLDIEKFMQGSKALQDAHVDA
ITMADNSLAVTRMSNLALGYLVQERLSARPLIHIACRDRNMIGTQSHLMGLHALGIDHVL
AVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFVVGAAFNPNV
KHLDKAVQRLERKIEAGADYIMTQPVYDAKLIEQIYEATKHLNIPIFIGIAPLASGGNAE
YLHNEVPGIRLSDEVRERMSGLKGPEGRAMGVEIAKELLDAAMPFFNGIYLMTPFLAYEM
CVDLTKYVWEKSNRHDFHLYPLSK
>A0A8J7X9Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeota archaeon|TrEMBL
MSLRERLERGDFVITLEISPPGDSAMDEFIRIARENKVDAINVPDNQRGIPRLSSLAASK
ILLDNKIEPIMHLSCANRNRTEMESLILGAEALKIPNLLIMTGDHPLVAKNREAKPVFDI
DSVDALRLAKEKSKLHLGAVANQMSNIELQAELVNRKVDAGAEFIQTQPVFDISRLEELI
DAASVKTKWIAGVMSIRSTKSAEFVSRKIPGIEVSGEITERLRNSKDPDKEGIQIMRDIL
DEFKEFGRISGVSLMSLSGIDIGEFLG
>A0A8J7X7X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeota archaeon|TrEMBL
MNFREKLLAGQFVVTGEIAPKKGVDISGIIEAIKHLRGVDAVNVTDNQRACVRLSSLAAS
KILLDNGVEPIYQLTCRDRNRIALQSDLLGAWILGIKNVLVISGDHPSLGDHPYAKPVYD
LDSVQLISTIKGLNQGQDLEGNKLNQPADYLIGAAANPGADDLDAEILKVEKKILSGAVF
LQTQAVYDVELFKTFMEKVKPLGIPVLAGIVPLKSAKMASFMNENIPGIHVPKHLIQELS
DSDNPTQAGIVQAAKIIKDVKKHCNGIHLMSLGWEDKVQEILQKAGLRQ
>A0A6N3TDF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
FSVTYGAGGSTREGTRRTVLQLDGEVKVPTAPHLSCVGDSREDLRNLINDYRANGIQRIV
ALRGDLPSGMGHASGELRYANELVEFIRAETGDHFTIEVAAYPESHPQAPNFETDLQNFI
RKAHAGADSAITQYFFNADCYFHFVDRVRQAGVDIPIIPGIMPITNYTKLARFSDACGAE
IPRWIRKQLEAYGDDSDSISAFGTEVISQLCERLLDGGAPGLHFYTLNQAEPSLAVVRNL
QGDR
>A0A2E9AWF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSLLKKALYERRFVCVVEFVPKPAVEHFAAYEKLMRHETLCGWPMVAAIADRVGSTFDIV
PLDAVGKLDKSVPALIHFSGKDREREALLEQLDRMDAMGLDQLLLLSGDRLPDHVPGQRP
VRYLESVPALQIVRQAKPTWLLGAALNPFKYHEEEGGAQYFKAEKKLAVGADFLTLQLGF
DAQKHLEAHQWMQQQATPVPLLACVMELTLKSAAILEHVPGVVISPSMRNLLAAEEAISS
AYARERSLARLGLQIIGLRLMGYAGIHLSGIRDPGQLKDLEQVIDAQMTDIQTLEQWSAA
WEASWRISGLSTVTFHPPQADWQLGKSYVRAAKKEQLRYHALSTLHSLLFSLNNPLSQGL
GWVLKRRFWRTPSGKHWLHRLERSLKRPVVGCDTCGNCRLEDTLYICPETCPKGLANGPC
GGTRLNRCEFGDRECIHSVKYRTAKVTGRTRVLTDNLIPCVDADSRHQSSWPRWFASLSE
GKRHDKGNSNDALEEA
>A0A8E6RS00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Shamba|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4R0D9C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4641|TrEMBL
MSALSHYLQQQQFCLVIEQIVSKRTELPPISTLAGLPCVMAFADRVHADDDPSPITLAQS
VCTEQAKLLHFSGKARDVKDLQQFVEQAKQQNMHDVLLLTGDKLKQHNFGKQDPLQRTRY
LESVSALMWVKAHAPDMYCGVAFNPFKYTESEEQAQYLKFEKKLKAGADFVITQLGYDLN
KILKFKKFVDASTQLCSVLACVMPLTYRRAKFMVKQQVAGIEISPHLLQHLKVEQQQNTA
WAEQRVYARAALQIWIYRHWGLAGIHVSGCQNSEQQALLEQALAQYQTWSVEQCLAEWNR
LCKVVRGDEMQPDLSAAYPQQQPSVLKYQVLHVTHDWLFDSTLAQKIGRFVFQQRFWQQG
LAAKGILAVEYASKHTVVGCESCGQCRLAETLYICPETCPKGLANGPCGGTHLDRCEFAD
RECIHSQKYRLAKQVGQQDILRCELIPAVPVEIRQTSSWVNWFNSESH
>A0A8J6TFT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfolinea nitratireducens|TrEMBL
MQEIRETFFDLLKSSPKPILADGAMGTVLHSHGVGFNQCFDELNLTNPALVGETHRAYIE
AGSQIIYANTFSANRYKLADHGLEDKVAEINKAGVELARRVVAASFRSVLVAGDVGPLGV
RLAPYGRVQIEDAKAAFTEQIAALCEAGVDLLVIETFGDLYEIREAVIAAREFCDMPIVA
SATFTQDDRTVLGDTPAKVAQALHKAGADIIGANCSGGPAQLFRILGQMKQAVPDTRFVV
KPNAGWPEQIGGRVMYSAGPDYFGEYTQSFVNLGVSILGGCCGTTPEHIAQMRIALDREV
SPVSQENLQIQIPSLDIDQIVPEQPTQLAQKFAAGEFVISVEMDPPRGLAPHKIIAGAST
LKEAGADVINVADSPRASMRMSPWAVCELIQRDVGIETTLHFPTRGRNLLRVQGDLLASH
ALGIRNVFVVMGDPTSIGDYPEAMDDYDLVPSGLMKLIAQRFNQGVDHAGSDIGQPTSFF
VGCALNLMPKNQEREIKVLRRKIANGANFALTQPVYKPEKALKFLKHYEDQFGKLEIPLL
VGILPLYGTRHAAFLHNEVPGIVIPGEIRQRIERAGDNAPKEGVRIASELAEEIKEWGQG
IYIMPAFGRYDLAVEIVDAVKK
>A0A840I2P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvularcula dongshanensis|TrEMBL
MSVHETPRRPLRVSFEFFPPKTEAMEETLWSSVEKLAPLRPDFVSVTYGAGGSTRERTHR
TVARLVSETDLPVAAHLTTVDATRAEVDDVLEEYWQAGVRHIVALRGDPPGGLGEAYAPH
PGGYANAAELTAGAKARHDFEVTVGCYPEKHPESPHFEADIEMLKRKVDAGASRAITQFF
YDNDVYERYLERVRAAGIDIPIVPGIMPVTNYKSLMRMAGLCGASIPRRVARLFENLDGD
PATRQLVAATVAADQCLDLAERGVGEFHFYTLNRAEMAYALCHMLGVRPT
>R7CRE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dialister sp. CAG:357|TrEMBL
MTTLRAKNKNHIFTITAELDPPKSASSEITEKQVAEIADYVDAVNIADCPMAKLRMSPIA
LSSIIQQKYCVESIFHLTCRDRNTIGLQAELLGAYALGVHNILTLTGDPPSIGDHPDATG
VFDVDSTGLIEIARRLNEGHDLKGNPLGAATNFYIGTTANPGADDLDKEILRLEGKKKAG
AQFIQTQPVYEISQAEKFLSYAKDLDLPILFGIVPLKSFKMANYLNDKVPGISIPQRILK
EMETGNRETGLKLASELVQGLKDIGTDGVHLMPVNDVDAVPVIVKNLK
>A0A352D133|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKKRVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A420Z405|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesebacteria bacterium|TrEMBL
MSFQELLDKDQFLIIAELEPPKGVDTSDFLKHADSLRGRAHAVLVPEMSGAIMRMGSIGA
SCLLKQKGIEAIVSMNCRDRNRLAIQADMLSIFSLGLENLSVSEGDDVTSGDHIEAKPVN
DLDVVSMLEAVKKLQKGIDLAGNDLSGIPQFCVGSEVNAGLAGGALEIEVMEMEKKIKAG
ANYFFTPTMYDLKALEDFAKKVAPFKVSVFPRVTILNSVGMARFMCRHMDGVLIPEEVLN
RLGKAPDKTKEGIVIAAETIQKLQNICQGVLLVAIGGQERLAAVLDQVGSLTA
>A0A437QWC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hwanghaeella grinnelliae|TrEMBL
MSKPAPDHATKIKLSFEYFPARTEKAAATLRRTASALDAMGPRFTSVTYGALGSNRDASI
NTIADVQDATAAPVAAHLTCSGASREEIHATADRFWDMGVRSVVALRGDAADDADAVRAY
DHASDFVAGLKKRHGFEVNVAAFPEGHPETSGPGLDGQLVDIENLKRKADAGADRALCQF
CFDDEAFLRYRDRAAAAGIGIEIAPGFLPIMNFRRLVDFSEKCGGTLPQWLWDRFAGYED
DVEATRRIAVEVGARQIERLRAAGVDRFHVFTLNKAALVQDIFRAAGVETRDRIAA
>A0A1T4RP88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga eiseniae|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMDFKPAYINVTYHRSEHMFKKK
ADGAFEKVEIRKRPGTVGICAAIMNHYTVDAVPHLICGGFSREETENALIDLAFLGIDNV
LVLRGDAPKNETFFEPDPHGHAYASELLDQVVHMNNGVYLEDDLQGGVKTNFCIGVAGYP
EKHFEAPNMQTDMGYLKKKVEMGADYIVTQMFFDNQKFFDFVAKCREMGITVPIIPGLKP
LTSKKQMNILPRIFHVDLPTELSSEIMRCKTDKEVEQVGTEWLINQSRELKAFGVPVLHY
YTLGKPQVVRKAVEAII
>A0A2N7UQR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas urumqiensis|TrEMBL
MTQQTQKGCDQQARGFAAKDPSGRLEQVLRAGNFAITTEIAPPDSANPQDVFDRAAVFRG
FVDSMNATDGSGANCHMSSSAMCALLSRAGFETVMQISCRDRNRIAIQGDVLGASALGIN
NILCLTGDGVQAGDHPQAKPVFDLDSMSLLETIISLRDKHQFLSGRRISDAPNVFLGAAE
NPFAPPFGMRAMRLAKKVAAGAQFIQTQYCFDLPRMRTFMHQCRDLGLLEKCFILPGVGP
LASARAARWMRQNVPGVHIPDAIIERLEGALDQQAEGRNICIEMIQALQEIEGVSGVHIM
AHRQESSVPSIVQASGALRGRTPWTPALNPLDQTQTAEA
>A0A0M0F840|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulosimicrobium cellulans F16|TrEMBL
MPDGGRARTHPGRSDVVSVADAVGQAHGGAARPTVSFELMPPRRPDAAPKFWETARRLVA
THPDFVSVTYGAAGTDRATARQVVGRLLQGTPVLPIAHLTCVGASREDVEEVISDFLDEG
VRSFLALRGDPPRDQPDWQPAPDGVRSSTELVALLREVEASRCASDPAAALRGAARPLTI
AVATFCDGNPAAGTTRTQEVRRLWQKQQAGASFAITQLFYDASSYTDFVAEARAAGVTIP
ILAGLLPTTEPARLRRVEELTGVRAPQHLLDALDALPDPEAQHAYGIAYTVDLAQRVLDA
GTPGLHVYTFNKHRAALDLLEGVHLGGGSAGTGGSTSAAAAPLVPDLASGPWVTGTSLPT
TSAATHGTPV
>A0A352E813|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
TKTEAGHEKLLATARRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQLDGEVKV
>U5DM86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubidibacter lacunae KORDI 51-2|TrEMBL
MLSRLHRAANARDFLVTAEICPPKGGDPQRMLKMAAALRSRVHAVNVTDGSRAVMRMSSL
AASVLLLQNGIEPVCQLACRDRNAIALQADLLGAHALGIRNVLALTGDPVKAGDHPNAKS
VFELESVRLLKAIGKLNRGYDANDKALPDGALDLFVGAAVHPQIKSWSSLQQRFERKVAA
GAQFFQSQLIVDFDRFDKFVTQIAAPCNRPVLAGIFLLKSAKNARFINKNLPGVAIPEDT
ISRLERAKHPLQEGLDIAAEQVRAARDICQGVHLMAVKREELIPEILDRAGIERL
>A0A420Z575|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesebacteria bacterium|TrEMBL
CIYNLDKFELWMQQARERGLHEKVAILAGVTPFKSAGMAKYMKNRVPGMDVPDEVVERMS
GVPKEKQADEGIKICIESIQRLKEVEGVRGFHIMAIEWEEKVPEIVEASGLYPRPDLG
>A0A2M4CSL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles darlingi|TrEMBL
KNKQSPVVAASLVRIAFTVAVRRYITSRSMSIAEEPAAFSLREKLSHIFQPTSGEAASSS
TRSVFYSIEIAAKDDFNIDQLRRLTPRPVFCSMPWISDENLRYEADFAQMPSLRLADQLR
QEQFTVVNHLSCYNLTEAHVDKLLSSQPSIRNMFIVRGDTVNPDQRFLHSAQLVQHLRQY
ESSRAATATKLTIGVGGYPGGHVESPSQEDELRHLADKVALGADFLLTQTLYDAASFFRY
RDRCRAAGITIPIIPGIYLPHSYRQLQTMLNITRVAMSPTVRATFEEHRDDTPEAFEAFV
VQYFVELVRELLQSNAIEPGSSDSVGLIHFFTFNKFNLLEKVISQLEFAQQERVGS
>A0A5J0WFK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Vitkin|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1B9F8M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dissulfuribacter thermophilus|TrEMBL
MKESILELLSHRVILGDGALGTYFYENGVPLSANLDLLNLQDPDLVASAHEDYVRAGSQL
IETNTFGANRFKLKGHVEKTVSVEDVVAQGVRIAKKVAGERLYVAGSIGPTGAFPMEEGG
EVSKEEVFESFSEVICVLLEEGVDLILLETFGFLEELLLGIRACRKQSADIPLFAQMVFP
SRGIAVDGNDAFFCAQKALAEGANGFGSNCGRGVKSMLEAFSLLEPLNGEVPLSAFPNAG
LPEIVGHRTIYSAQPSYMASGIAEMIKMGARLVGGCCGTSPQHIAEFKKRLHLKGPSRRA
SIFVGTKENRVEEKAASNAPGALIRSLPKKRIPILVELDPPTHLDCGDIILGAKELKAAG
VDAVTLAENPLAILRTDNLALARLIQEKAGIDTVVHMTCRDRNVLGLQNRIMGAHLLGIK
GILAITGDPATASDQPGTSGVFDLDSIGLVRTIQNFNRGINLAGRSVKVKTDFSIGVAFS
YRPKNPELQLKRLKRKRDQGAHFVMTQPLFDKGEIESMMELVGDMGLVIFPGIFPLISAR
NAEFLHNEVPGISVPKSIRDRLWRYEKVEDQRKVAFEMTFNLVESILKIVHGLYIISPLN
KWKVAKKLIVHLSLS
>A0A5N9BTZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MSGQLEEQSKLERVLRSGQLAVTAEINSPDSSLPESVHRNALVLGSLCDGINATDASGAN
VHLSSIAVSAILQKAGYEPVMQISCRDRNRIAMQGDLLGAAALNIKNVLCLTGDGVQTGD
HPEAKSVFDMDSINLLKMTRTMAHEGRFLSGRKLESKPKFFLGAAANPFVPPFDFRPLRL
KKKIDAGAKFIQTQYCFDVPRLKTYMDAVNDMGLSEKAFILIGVGPLKSAKSAQWIRSNV
PGVVIPDAIIRRLKQAKDQAAEGKKICLEIVQQAIEMPGVKGIHIMSYGQEELVPEIIAE
SGILDNRNNNI
>A0A0Q6MC30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. Root102|TrEMBL
MIGRQRDENPDGIHLPLAPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIASGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSIIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A1X7GN10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium oryzae|TrEMBL
MTALREPFSVSFEYFPPKSDEMERQLWETVEQLSVWEPDFITMTYGAGGSTKEPTLAAVK
RMIGEMDLPTAAHLTCVDASREEVRAVIEDFRAAGVRRIVALRGDPTTGVGTAYAPHPQG
YSRTADLVRGLVEYGDFDISVSAYPEKHPESPDIAADIETLKSKADAGAHRALTQFFFDN
DVFERYLEKVRAAGITIPIVPGIMPIQNLAQLKRFARRCGASVPAFLDARLDGLDEKPEE
RAEVAADIVAEQIEDLIRRGIHDFHIYTMNRAPLVSAVLQRLGRGEFRGARTAAA
>A0A5N9F2X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MKITEGCFEATGHTSIICDFSPPRSGDPVAVEQAQIDADFISVAYNPGRAVRTNSAMLAA
AIQRSGKDAVFTLATRDMNKLALQSELLGAQMLGLRNVVVVQGDPFGQQDQARVASVNDY
HPTGLIAAIAQMNQGVDFKEGQLRSPIDFCIGATIDLSRGIEEEAQLAVRKVQAGAEYLI
TQPVFNVDHVAQYWESYAYHSGKAGIPPIYFGLQILEKDCVLFSSVPESVRGELEEGRSG
ADIALELYQKFQEARLNNIYLVPPIKPGGARNYEAAKAFLGKINKR
>A0A2V4V7P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PP-F2F-G20b|TrEMBL
MSGFPSASGDLLPGHSSRGRLEQVLRRGEFAVTAELNPPDSADPEEVYARAAVFEGWVDG
INAVDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQGDVLGAAAMGVANILC
LTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDHAKFLSGRKLTAPPRVFLGAAINPFA
PPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFRAYMEKVRDLGLHEHCHILVGVGPMASA
RTARWIRSNVPGVHIPDAIIARLEGAADQKKEGKQICIDIINEVKEIKGVSGIHVMAYRQ
EEYVAEIVHESGVLKGRRPWRREQDPADAGVAERLDAARGGEMQDQESLAETAAKRPH
>D3FCP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Conexibacter woesei (strain DSM 14684 / CIP 108061 / JCM 11494 / NBRC 100937 / ID131577)|TrEMBL
MRIDEIIAAGGDPVFSFEFFPPKTEEGEARLFAALEALRPLEPAFVSVTWGAGGSTRAKT
IDIVSRIRANHDLEAMAHFTCVGATTDDLRGDVARMRDAGIENVLALRGDPPQGETTFVA
TEGGLSYSSELTALVGETYPEACLVGACYPEVHSEAADRESDLAHLKAKVDAGVRVLITQ
LFFDNAAYYRFVADARAAGIDVPIVPGIMPIISTAGIKRMTSLCGAKIPPALLAALEQRG
DDAEAVAELGVAYATLQCAELLANGAPGIHFYTINRSPATRAILSALRLQRPWDASAGTE
PALRVLAG
>A0A507WEQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxellaceae bacterium AER2_44_116|TrEMBL
MSRNIPISFEFFPPKTDEGAQKILQVHKQLCTLNPSYFSVTYGAGGSTRERTLSTVDSIQ
QASTIAVAPHLSCIGDNKAEVSALLHRYKNQGIKHLVALRGDLPSGQVGLGEIPYARDLV
EFVRQETGDHFHIEVAAYPEMHPQSADYQADLTNFINKAKAGANSAITQFFFNPNAYFYF
VEQVRKTGVNIPIVPGIMPITNASNLIRFADGCGADVPRWIRKQLAAYGDDSASIKAFGE
EVIAKLCETLIQGGAPSLHFYTMNMAQPTTRLCKMLGLG
>A0A5N9B5W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MPTKSTRLNQNKFIYTSELTPPKGIDLSKLINTASNLNMIDAFNITDNHNSKMTMAPIGL
ARKLIENNIEPIYQITCRDRNSMAIQSDLLAAYSLGINNILCMSGESVKYGDHPNAKDVF
ELSSEELIETITKLNNGYDYANNKLDSVTNFNIGAVVNPGSNTIEKELKKFENKIKNGAT
FFQTQAIFDPKTLNNIIQIKQNKNIKILAGYIPIKSVKMANYLNNKVPGIQVPENIINLM
KKTDDPQKTCIEISKEIISEIKAIKGIDGVHIMALGWEHLIPKMI
>A0A013TIZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 742879|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A5N9G6L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MACICEYVRDPQYGSASMAKVADHAMSNDGKLNIVCDFSPPRGGNPGLLDGAASLDPDFL
SIAYNPGRSVRINSVAVAAWVKANMGQDVIFTIATRDMNTIAIQSLLLGAQLLGLENVVV
VQGDPLTARDRERLTQVNDVRPAELIESIQGMNEGIDFRGLKLRQPTSFCVGATIDLSRG
LDAEAALTRRKVEAGAEFFLAQPTFDAKISQGLSDVYARDFGEELAAPVHHGVQIMSADG
VRFADIPKWVTHDLDSGRSGEDIALQVIRAYVDAGITHFYLIPPILRGGRRDYAAAARVM
ATARQAVP
>A0A1I0NXQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliiroseovarius sediminilitoris|TrEMBL
MTTPNISFEFFPPQSLDASFRLWETVRELAPLDPSFVSVTYGAGGTTRELTHDAVQTIHK
HYDLNVAAHLTCVDATRDETLAIAKDYAQAGVTEIVALRGDPPKGSNGFAPHKNGFASSV
DLIEALAETGDFHIRVGAYPDPHPESADLDANVAWLKRKVDAGANSAITQFFFEDDTFFR
FRDKCEKAGIDVPIIPGILPIENWNGVRKFAERCGAYIPAWLDDAFAKATRDGREDLLST
ALCTELCSDLIDGGVKDLHFYTLNKPALTREVAHALGITPPMKLQDVA
>A0A7G8PZS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella telluris|TrEMBL
MPPISFEFFPPKTDEQRAQLDQAANLLKAHVPEYVSVTFGAGGSTLSYTGETVHRLHATH
GLAVAPHLSCVGGTRAELAALLDDYRAAGYRRIVALRGDLPSGMATPGDFRYASELVRFI
REHSGDHFHIEVAAYPETHPQADDALADLRHFKTKVDAGANGAITQYFFNPDAYFRFVDD
VQRLGVNVPIVPGIMPIANFSQLKRFSDMCGAEIPRWIAKRMQAHGDDAASVRELGADVV
AQLCRRLLDGGAPGLHFYTLNRARATRAILDRLHG
>D5HJ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. ART55/1|TrEMBL
MKIRDLITQDKATLSFEVFPPKKDTDFADVEAAALGIAAFKPDYMSVTYGAGGSTKGHTI
QLAQEIQEKYDVPTIAHLTCVCASKEGIKTALADMKNAGIENILALRGDIPKNYDGQVFA
EFSHASELVELIKETGDFCVGGACYPEVHPDSANKHEDIIGLKKKVDAGCDYLTTQMFFD
NNIFFNFMYRIREAGISVPIIPGIMPITRRVQVKNAVKLSGCNVPERFKSIVDAFGDTEA
AMRQAGIAYATDQIIDLMANGVKHIHVYSMNKPEVAAGIQKNLSEILKI
>A0A427TMI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesobacillus subterraneus|TrEMBL
MNFLKRMENEILIADGAIGTLLYSYGAGTCFEELNTSHPDDIIQIHKAYMDAGADLIQTN
TYAANYIKLERYGLEDQVKEINSAAVKHARLAAGKDAEILGTIGGNRGIRPSAIPIEEIK
RSFREQLYCLLLQGIDGILLETFYDMEEIETVLAIARKETNLPIIAQVSLQEIGIMQDQT
PLQQVFNRLEDLGADIVGLNCRLGPHHMISSLEQVDLPAKAFLSAYPNAGLPAYTDGKFH
YEGTPEYFKKSARSFREQGVRLLGGCCGTTPEHIRAFAQEIKGLEPVTEKKVPVKQRKIV
VASPDVKRPVPPLHQIAKERPSVIVELDSPRKLDTTRFFEGAKALKETGIDALTLADNSL
ASPRISNAAIGHLLKEQIGMRPLVHLTCRDRNIIGLQSHLMGLHTLGLHDVLAVTGDPAR
VGDFPGASSVFDVSSFELIEMIKQFNSGLSYSGKDLGQKGAFSVGAAFNPNVRSLEKAVL
RMEKKIEAGADYFVTQPVYSEKLLMEVREATKHIDAPVYIGLMPLTSSRNAEFLHNEVPG
IKISQEILETMAKFNNEPLQSKREGIAITKELIEAAAELFNGIYLITPFMNYEMTVELSR
YAHEYSSLVSRRKQNVNIVN
>F5LF75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. HGF7|TrEMBL
MKPELRQVLAQKILIGDGAMGTYLYQQGFPVGISYEELNLIQSEVVADVHRRYYEAGARL
IETNTFSANREKLSKYGLEQEVEAINRAGVELARSSVGEDAYVVGAIGPIRAGMRKNVRT
ADVEDALREQILVLLDTQVDGLLLETFYDLEEMLIALRLIRQLSSIPVICQFATEGINTT
HDGISLQDAFLRLKEEGADVIGFNCRTGPNGILRSLQGVAQLSDIPFSVFPNAGIPDYVD
GRYSYAATPEYFAESALRFADLGARIIGGCCGTTPEHIAAMVKALQGYEPNRSEVYAAES
VSAAERAVVTEAAPQTSVREADVEPTLVDLVKQRHTVIVELDPPRDLDIGKFMEGTKALQ
DVHVDAITMADNSLAVTRMSNLALGMLVKEQHGARPLIHIACRDRNSIGTQSHLMGLHAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEMIRMIKQLNEGIAFSGKPLKKKANFIVGA
AFNPNVKYLDKAVQRLERKIESGADYIMTQPVYDPKLIERMHEATKHLDVPVFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMTGLEGEAGRKEGVAIAKELLDAAMPLFNGIYFMTP
FLFYDMSVQLTQYVWQKAERRELLLSPLLK
>R7D7U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. CAG:289|TrEMBL
MKVADIFSNAKATGAQPISFEMFPPKGELTLEHAREVAEQFQDLHPDFVSVTYSAGGSGN
SGATAKIASMLAHDFDITSVAHLTCISLTHDELQRKIEEMRQAGVENVLALRGDLPQGTN
AADAARAEYPYAKDLIPALVDAGFCVGAAAYPEGHITCENLELSVEHLKQKQDAGASFFV
TQLFFDNECFFRFREMADRVGITVPITAGIMPFMSKQQISRMVFMCGASLPSPVIKLLAK
YEDNPDALREAGIEYACRQVGGPRGAGGGGLPLYMRDAGADGLHIYTMNRPSVARAAIEA
LRK
>A0A6I4AZ73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium japonicum|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVGRILNETSLTPAAHMTCVDAARHQVDAVIQEFAAMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>C0GF40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dethiobacter alkaliphilus AHT 1|TrEMBL
MTLSNLQKALKSGEFIVTGELGPPKSAERDKIEHHGHLLGGVVDAINLTDNQTAIVRTSS
VACGKILIDMGLDPVIQITCRDRNRIAIQSDVLGAAALGIKNILCLQGDHANFGNEPNAK
NVNDLDSMNLIQTLKNMRDEEVFIGGEKLEAPIDICIGAVENPFADPFEYRAYRLAKKVE
AGADFIQTQAIFDMDRFERWMEKVRELGIHKKVPILAGVIPIKSLGAARYMKNNVSGMIV
PDEIIDRIKGAEKKKEEGVKLCVEMIEHLKTVEGVAGIHLMAVAWEEIVPEICERAGLLP
RPKFD
>A0A1Q8FJ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maricaulis sp. W15|TrEMBL
MSADGQTARNTNGLAVSFEFFPPKTDAMEATLWESISRLEPLQPDFVSVTYGAGGSTRDR
THRTVHRIVEETSIRPAAHLTCVSATREEVDTVIRDYWRSGVRHIVALRGDPPDAIGGAY
VPPAGGYANAAELSRGIRDVGDFEISVGCYPETHPESPNADFDIDLLKAKIDGGATRAIT
QFFFDPDIYFRFRDRAARAGITIPIIPGVMLQPNFKGLKRIAGLCGASLPNWLHEAYEGL
DDDAGTRQLVTAHVAAKLCGKLRTGGVDGFHFYTLNRAELALSTCQLLGVKACERESEAV
AS
>C3MEQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium fredii (strain NBRC 101917 / NGR234)|TrEMBL
MNARTLYPAERGNLGLSFEYFPPKNEEMEIQLFQTVADLAIFAPTFQTVTYGAGGSTKAR
SLTTVKRMIGEVGLKNTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGSA
YQPFPGGYESSAALVKALRARGDFEISVSAYPEKHPESPDVAADIDMLKRKVDSGATRAI
TQFFFDNDDFERYLERVRRAGIHVPIVPGILPINNLAQVVRFAGLCGSKVPEAIISRLAH
LDDQPEERFKEASHIAAEQIVDLARRGVRDFHLYTMNRSPLIAAVCDLVGYARRPANRTA
APSYRAVATA
>A0A1B8TR54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter vadi|TrEMBL
MKITEHIKKANGKTLFSFEIIPPKKGKSIQELYNNIDPLMEFNPPFIDVTTSREEYVYVE
KEGLLDRKMTRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIENV
MALRGDAMSHQKYFEASKGGHQYAKELVAQIQNLNCGKYLHDVIEADNCADFCIGVAGYP
EKHLEAPSLQSDLKRLKEKVDAGADYVVTQMFFDNNKYFQFVDAAKKAGINVPIIPGIKP
LAVKRHLQLLPQVFRIDIPEPLINAVESCKNNKDVRQVGIEFAIQQSKELLAAGVPVLHY
YSMGKSDNIQAIAKELF
>A0A1Y3KS31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 1239|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARTLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHIEVAAYPEMHPQARHFEDDLINFVRKVKAGADSAITQYFFNADCYFH
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVQSIQAFG
EQVITEMCEKLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A2E1LSC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium|TrEMBL
MIPDNNSAGAARAAPLVSFEFFPPKNDKMAARLWESVSRLEAMAPDFVSVTYGAGGSTRD
RTHETVRRMARETSLSPAAHLTCVSATKQDVLNVADAYWQAGVKHIVALRGDAPEGMGQK
FEAHPNGFRDSIDLIEGLKENAANNSHKFEITVSCYPESHPDSRGPDADIAFLKAKQDAG
ASRAITQFFYDTDIYLNFLERARAGGVTMPIIPGIMLQPNFEGLKRIAKLCAASLPDWLH
KLYEGTENDSETRDLITANLAAELCQKLQEAGIQNFHFYTLNKAGLALSTCHLLGLKPQT
TGVAQ
>A0A0V1MUG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella papuae|TrEMBL
LMASLEAVELKTTRHDLNSSPKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTPEGL
INLLNRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCVLNFCLLDTMLHITSVQY
NEKTVLSNLERVKKIGIRNILALRGDINDDANVTATDFQYACQLVQFIRSHYGDYFTICV
AGLYLCAKVDAGADFIITQLFFNEMHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMKIV
QLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVELCRKLLNAEQHVVPGLHFYTLNQEK
SILEQIGLWKKAPGRILPWKKHPVHSVRCREAVRPIYWNARPKSYLCRTRDWKQFPHSRW
GDLGNPAFGDLKHYLFSCIDQMNDSRALDMWDKELSSFKHVRDIFCNFIARTPNRHGHTV
RRLPWNENHLDPAVDILKDELIYYNSNGILTINCQAAVNGLPSNDPIFGWGEANGYIYQK
VDDAQCILISLGYLEFFASSKCTTILLNHVQNFPSVNYHAINFDGSFETLNYDEEATMAL
TWGVFVGQEILQPIVANAASFRVWKVVAELSFIQFAMYFFLFFEQDEAFDLWQRWARLYE
SGSIGRKLLQSIHDDHRLITLIDNDYPQPCSLSALLRAVISEYCEEKN
>N1WE15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira weilii serovar Ranarum str. ICFT|TrEMBL
MKKISEIYGAEKGPVYSFEFFPPKTPEGDLKLMETVKELSRLDPDFVTVTYGAGGSTRDK
TVQILSEISRNYSFPTVSHFTCVGADRDRILEILKGIRSSGIVNLMALRGDPPKGEGEFK
KTEGGFENATELVSFIRSENLDFCIGGGCYPEKHPDAKTLEEDVRNLKLKVDAGTDFLVS
QLFFVNSIFENFLNLARKVGINVPIIPGIMPITSFSQIERFRSMAGCGFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGGSL
>A0A0M4RSM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter alpinus|TrEMBL
MSPPSLIQATPSSGAGAPIALSYELFPPRNEAAAASLWDTIGELECTNPDYVAVTYGANG
SNRDTAMDLLNRILTETSLRPLAHLTCVGSTADELAEVISELLDHGVRGILALRGDLPKN
APAEPRAGKLEYAQDLIELIRRVEQRRSALLCAGKVAIGVAAYPTRHPESPSVEHDVEVL
LAKQRSGADFAITQVFFHASQYKDLVTRARRAGVSIPIIPGVMPLTSLRRVQRLGDLTGV
APSDSLLDALGRADNAAESRRIGVAATVDLARDALDAGAPGIHLYTFNEHAAALDVLDKL
QLLRPGRPLVGRRLGAGAQLVQA
>A0A3A6PGR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfarculus sp|TrEMBL
MSKFKEALAAKDFLLTVELDPPRGPELGPLTELAGQLAGRVDAVVVSDNRGARARLSPLL
AGQALVKHSGAEVIMTLTCRDRNRLALISDLLAAAAAGVENLLLVSGDFVSLGDQPGTKP
VYDLDSVQLLQLAAQMAQGRDPAGELAGPTPFFLGASLAPEARPLGPQVMKLKKKLAAGA
GFLITKPLRGLAGLKEFAAAAGELPVKLIAGVEVAAGAEPAEVLSLAREVKAAGLAAGVH
LAWPEQPQRLPDLVGQL
>A0A2E0E939|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriaceae bacterium|TrEMBL
MVRLSSVLQSSLEAGAVTITAEVMPPRGGDASHALEMARSLRGRVHAVNVTDGSRAVMRM
SSLAVARLLLEEGIEPVLQMACRDRNRIAIQADLLGAHALGIRNLLCLTGDPVRAGDQPK
ARHVNELESVRLLEQVSALNRGEDPVKGDLVDGPTSLFAGAAADPQCLSWTGLARRMERK
KAAGARFVQTQMVMDAAALERFCREIAEPMQLPVLAGVFLLKSARNACFINRMVPGACIP
DNLIARLEAAEDPAAEGIRIAADQVKQYLGLAQGVHLMAIKAEERIPTILDQAGVSLIA
>A0A2S8UX59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. MYb209|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTERNAIVGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVVPVIAKETIQRPTVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEEPIFIGIMPLVSKLNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>Q8G652|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum (strain NCC 2705)|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A1E3KR91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAASRLKLTRYDLQDQVTTINQAAVKIAATAREHADHPVYILGTIGGLAGDTDATVQR
ATPATIAASVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGKPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFIGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A3R1BTW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Kidderminster|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0A7FY38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium baratii str. Sullivan|TrEMBL
MNIRELFDCKRLVLSFEVFPPKNTSPVKTIYKALNELSTLKPDFISVTYGAGGSLINNKT
SEISSLIKNVYNIEALAHLTCISSKKENIDDITERLELEGITNILALRGDNNDNGAGEYK
YATDLIKYVNEKEKFNIISACYPEGHIENKGIEAEIMNMKRKIEYGTSSFISQLFFDNNI
YYDFLDKAKGSGVNVPIQAGIMPVVNKKQIDRITSLCGATIPLKFKKIMEKYEYDSEALR
EAGIAYAIEQIIDLASSGVDGIHLYTMNNPYVARRIKENIEVIVKSINNKGETIA
>A0A1M7B823|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium saccharophilum|TrEMBL
MKVTEHIENAKGNTLFSFELIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKLGGNHFAIDLVKQINNLNCGKYLHEVMDVDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQIF
>A0A1Y4BBI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olsenella sp. An293|TrEMBL
MRIIDKLAARQTFSFEIFPPKGEMPLETAYAIADEMARDRPDWISVTYSAGGSGNSANTV
PIAASIERDLGVTALAHLTCLGSERADVDAYVAALEASGIENVLALRGDRALGREARDFA
HASDLIAYLRDSGSTLCIGAACYPEGHVESPTEQESFESLYKKQEAGADYLVSQLFFDNE
DFYRFREKCLRHRVRLPIVAGIMPFTSVTQIQRMAFTCGASIPAKVVKRLVLAGDDPADQ
ARAGVEYACEQLCDLAANGVDGLHVYSMNKPSVAHAAREALLGCGYLEA
>A0A2G2HVQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp|TrEMBL
MTKQLTISCEFFPPKSDKGIAILRDVREKLAPLKPDFYSVTFGAGGSTQDNTLDAVIDIQ
QASATTGIDAAPHLSCVGSTEDNIKNILQTFKDNDIKRIVALRGDLPSGMRDPGDFRYAN
ELIDFIRKETGDHFTIEVACYPEIHPQADSAQADLDNFKRKVDAGADSALTQYFYNVDAY
LYFVERCQKVGIEIPIIPGIMPINNFSQLARFSDGCGAEIPRWLRKRLEGFHDDTESLQA
FTLDFLTGFTEKLIDAGVPGLHFYSMNRVDPTLTICQRLGLVK
>A0A519PUE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MAANLAEARALLLSPLGPVARAGSNHNPVRVSFEFFPPKTDEAEANLWKAIRRLEPLSPA
FVSVTYGAGGSTRERTHRTVQRIITETTLKPAAHLTCVEASRDEVDEVIAGYKSIGVDHI
VALRGDPPGGAGIGGVYAPRADGYANATELTAAIGRVGGFDVTVGAYPERHPESPSIEHD
IDVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGIMPVSNFTGLARMCG
SCGASIPDWLRAHFEGLDDDPETRKLLAASVAAETCARLQEEGFADFHFYTLNRADLVYA
ICRVLGVRETAQ
>A0A0S4LBH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrospira nitrificans|TrEMBL
MSREPQRLIDVLNRGTFAVTVEYNPPKGTNISSVLENAKQLVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGKDMVGNKLDGSTAFTIGAAVTPEADLVGPVLAKFEVKV
KAGAQFFQTQAVYHPAVFASFMKHVRPFNVKVLAGILLLRNAKMAEFMNANIPGMSVPNE
MIDELKAAGEKAEDVGVDIAVRTIKAVRPHCDGVHIMAIKATHRLAEIITKAELN
>A0A0A2N171|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium subsaxonicum WB 4.1-42 = DSM 21790|TrEMBL
MKVTEHIENANGKTQFTFEILPPLKGQNIQSIFDSIDPLMEFDPPFIDVTYHREEYEYKE
LPNGLLEKKVVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VVALRGDAVKSEMYFKPEREGNNFATELVTQVANLNKGIYLDDHLQNTSATNFCIGVAGY
PEKHMEAPSMDSDIYFLKQKIKNGAEYIVTQLFYDNQKFFDFVAKCRKEGITVPIIPGLK
PIATKKQLNLIPHRFKVDIPDDLIMDVVRAKDNDAVKQVGIEWCIAQSKELVKAGIPVLH
YYSMGKPDNIKAIAKEIF
>Q5A5S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida albicans (strain SC5314 / ATCC MYA-2876)|TrEMBL
MSTVAERIASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTS
EKSLDLAATCQNEIGITTVLHLTCTNTNKEVIDQALSRAKAAGVRNILALRGDPPRTEEY
WTPNCDFNGAVDLVKYIREKYGDYFCIGVAAYPEGHVDGSDTSSQNPQRDIPFLVEKVKA
GADFIITQLFFDVEKFIAFDKLLKEHDELKGIPLIPGLMPITTYKVFNRAAKLSHASIPK
EILKQVDQVCHDDNAVKALGVDILSEMIDQIDKSTTIKGYHFYTLNLEKAVASILDKSDV
LRQVLEGPSYATRFEDAVASDSDDEDEPEKASERDITLTKTIKPRRVSSINDNELTSSKA
LVGKALLNDKKVLVDISTGKGALGKDAIWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHTP
AEASTKWGTPESIADLTQVFINYLSGKVDVVPWADSSLSPETALIQEELFQLNEKGWFSV
ASQPAVNGCKSTDNIFGWGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNK
DGEIKSNLPIGPNVKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLWLEWARCY
KKNSKSFELLNSIYENYVLVSMIHHDFINENALWDLLLDE
>A0A544VCH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. SDF0028|TrEMBL
MKNFREALHEQIIIGDGAMGTYLYQLGYPVGISYEILNVTDPEVIRNIHKQYVDAGAGLL
ETNTFTANREKLYRHGKEHLVKDINRAAVRLAREAAGNQAYVIGALGSIRAGKRENVHTN
QVIRDYHEQMSAMLEEGVDGIMFETFYDLEEMRLALQVVRELDQDVPVICQFAVEESRRT
KDGKSLLEAFRVLRDDGADVVGLNCHMGPNGVLRALEGVQGRIDLPLSAFPNAGLPDYVD
GRYNFVASAEYMAQSAVKFVQMGARIVGGCCGTTPEHVAAIVEALRDVEVPELPVQPVES
IIIEEESESMLWHDGAPCYDGCDHGHDAEESIVDMVRSRHTVIVELDPPRDLDVSKFMKG
AQVLKEAGVDALTLADNSLAVTRMSNLALGYMALDKVGIRPLVHIACRDRNLIGTQSHMM
GLHALGIDHVLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNSGLAFSGKPLKQKAK
FVVGGAFNPNVKHLDKAIARLERKIEAGADYIMTQPVYDKDLIVRIAEGTKHLNVPVFIG
IMPLASGRNAEYLHNEVPGIELSDEVRSRMSGLEGEAGRKEGVAIAKELLDVALTHFKGI
YFMTPFMFYEMTAELTQYVWEKAERQADPLYRLT
>Q5AEI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida albicans (strain SC5314 / ATCC MYA-2876)|TrEMBL
MKISEKLTQAHKGSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALEKAFKSGCQNILALRGDPPLD
GSESTGDFKYAKDLIKYIHEKYDNHFNIGVAGYPEGHPEEEDEQKTLRYLKEKCDAGADF
IITQMFYDVDNFISWCSKLRKIGVDIPIIPGIMPISTYAAFIRRAKWSEIAIPQHFLDAL
DPIKDDDFLVRERGTELVSEMCNKLLQSGYVNHLHFYTMNLEKATVMILEKLNLIEAIKS
HDVVGGSELPWRKSLHPERSKESIRPIFWQHRKYSYISRTATWDEFPNGRWGDSRSPAFG
DIDLCASELLRQSPKKAFELWGLPQSLAELSGIIINYLKGDLKSLPWSDGPVGDDTKVIV
DDLIYLNQHGFFTMNSQPALNAVKSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDH
VEEFNVKGAESSSAFISYYAVDKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSF
LAWKDEVYRLFTEWAKIASSNLVEANQTQVDEFVQLMKKFGDEFVLCNLVNNDFVDGNST
LFDLIKRLNIDDLN
>A0A847UPS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrionales bacterium|TrEMBL
MHIGSLLNRQEPFLSLEFFPPKDRGQWPGFFDVVRQLKTLAPLFCSVTYGAGGSTQHNTL
EIVARMKQEYGLEPLAHLTCVGADVARLASFMRGLNEARVDNVLALRGDPPRGETAFVPD
SDDFQHGSDLVSFIRKDFPSFSIGVAGYPEKHPEAASAEKDLQHLRHKVDSGADFIITQL
FFDNDAYFDFVGRARAIGINVPIIPGILPVQNLPALKRMLSFCGATVPEGFMRDLEHVQA
TYGESGVRGLGLGYAKAQVRNLLDRGAPGVHLYTLNKADTCLEIWRDFSLRDGRQ
>A0A6I2G595|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia sp. SYP-A9097|TrEMBL
MSFDNVQGYSTPGRVFRTPQGSGTRSVIQQLGPRPDGSVPFSVEFNPPRDAAGEARLWRA
AREFERLHPAFVSMTYGAGGSTRDRTIRVTGQLARETTLLTVAHLTAVDHSVAELRSIVG
AYADSGIRNLLVLRGDPPGDPLGDWVKHPEGVEYAEELVRMVRDLGDFHVGVASFPQGHP
RSSDLDQDTGHLIAKLRAGAEYSITQMFFDPEHYLRLRDRVAALDPAEGDKPIIPELMPI
TSLRTVERAVELSGRELPVKVLERLRKAAGDGPEENRAAVRAAGIEIATEMAQTLIDEGA
PCLHFITLNFAKATGEVLANLGYTVSANSISA
>A0A4Q1SD39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidipila dinghuensis|TrEMBL
MNERIRALFGDRTILCDGAMGTTLYARGVFINRCYDELNLSQADLVRSIHDEYLQAGAEV
IETNTFGANSFRLLRYGLQDQVFAINKAGAELARQAVEHHAGKHAGKAFVAGSVGPLGVH
LEPLGKTSLEEARVAFAEQIRGLVAGGVDMLAIETIVALNEAEQAILAAKEVAPDLPILA
MVNVDDEGNCLDGTSPEIAATRLAAWGADIVGCNCSTGPATILTALEKLAAGTSLPLAAM
PNAGMPRAIDGRNIYLCSPEYMASFARKFLKAGAQFIGGCCGTTPNHIRAMRAALRAADA
QKVSVQPTAKVEIVSEVVPPPLAQRSKIGQLIHDGAFVTMVEIVPPRGVDASRELDGAAM
LASHGIHAINVPDSPRASARMSAQSLCIQIQQKTGIETILHYTCRDRNVLSIQSDLLGAS
SIGLKNILCLTGDPPKLGNYPDATAVFDVDAIGLVNIVQRLNHGLDIGGNPIGSSTGLTI
AVAANPGVPDIENEIRRFAYKVEAGAEYAITQPVFDLRILEAFLKRIEGFRIPIVAGIWP
LTSLRNAEFMKNDLRVSVPDSILLRMQQAATPDLARAEGIKIAQEMLAATMPMVQGVQVS
APFGRYPLAIEAIKDVLPKPQSVEELPAAQAITA
>A0A533ML86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|ANME-2 cluster archaeon|TrEMBL
MGLEEAIRSGKFIVTAEICPPKGTDISGLFSEAALLQGIVDAVNVTDCPRAMVRMSPLVL
SSELIKMNIDTIMHLTCRDRNRIAIQSDLLAAHALGIRNVLAMSGDFTTMGDHPYAKPVF
DLDSVQMLQVITKMNRGFDLMDNPLGGATSLYAGAVVNPGARPLGFVRIKLQKKISAGAR
FIQTQAVFDADLFNEFMDEFKSLNIPVIAGIIPLRSAKSAGFMIENIPGVKIPQAAINRM
ESASDPVTEGLKIAAETIDRIKENCQGVHIMPIGNHDHTKRLLEMCSLL
>A0A4T0VR06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum higginsianum|TrEMBL
MHIKSMLDETRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREQEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDGDNFVRWVGKVRERGINVPIIPGIMPIATYASFIRRAKHMNCKVPDDWMAAL
EPIKNDDVAVREVGKGLVADMCRKIVAAGIHHLHFYTMNLAQATRMVLEELNWMPTSDRP
VKHALPWKQSLAHGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPRSIKDVANIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSTHPVHGWGPANGYVYQKAYLELLVHPDVYAEIVSRVEKNP
DMTYYATTKNGSLKYNATHDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGIDW
AHCFEAGTPSRVLIERIMNEWYLINIVNNDFHQKTALFDMLEGLEVKEYADIPAEPQTNG
AVETNGNSVSATPN
>A0A329CPX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces avidinii|TrEMBL
MRELLATGETSFSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRAGTVRA
TQQIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVRYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDSDIGHFVDKCRAGADYAITQMFF
QPESYLQMRDRVVAAGCETPVIPEVMPLTSVKQLERFAQLSNASLPSALKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>R5VEJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:18|TrEMBL
MKISDACNHKKSLSFEIFPPKKDSELKNIDATLDVLCELQPDFISVTFGAGGSLNCNRTI
ELAKKIKQNYHVEPVVHLTCLHYNRAEIDEFARILTAEGIQNVLALRGDRNPDLTEKDDF
KHASDLISYLKPKGDFCFLGACYPECHPESANKIEEIRHLKEKVNAGAEVLLSQLFFDNT
QFYRFVEDCRIADINVPIVPGIMPVINAAQIKRMITMCGASFPERFQKIIHRFEDNKAAL
FDAGMSYALSQIIDLLANDTDGIHLYTMNNPVVARRICEGIQHII
>A0A1G3IB69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium RIFCSPLOWO2_12_FULL_58_28|TrEMBL
MGDPVALSGDIAVSFEFFPPKNEKMETALWDSVQRLAPLGPRFVSVTYGAGGSTRERTHA
TVTRIRKETDLEPAAHLTCVGSSRDEVDAIARRYWEDGIRHIVALRGDPPEGSAAYRPHP
DGYAYAADLVKGLKKIADFEISVAAYPETHPEAKSPKADLDNLKRKIDAGAVRAITQYFF
DPDVYLRFLDRARAAGITVPIVPGILPVTNFKNLIRFSANCGAAVPDWLGKMFDGLDDDP
ETTKLVAAALAADQCRKLHDNGVDQFHFYTVNRADLTFAICHILGVRPK
>A0A1G9ETR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora mzabensis|TrEMBL
MTRVVDRLQPGRTVFSVEFFPPRNDDEEQILWKAVRELEPLDPAYVSVTYGAGGSSRDRT
IRTVGRIAQETTMLPMAHLTGVDHSKDELRHVVGSLASEGIQNVLAIRGDPPGDPMGEWI
PHPDGILYADELVRLIRSWGDFSVGVAAFPHMHPRSTDIETETDHLVNKIRAGSDFAVAQ
LFLQPEYFLRLRDRLAARDCHAPLLPGVMPITTPKVLSKFQHLAGVPVPTEVSNVLDPLV
EDPKAFRAAGIELSTKLCERLISEGVPGLHFYSLNRAKATREVVDNLGLAEGVLQPA
>A0A2A6M416|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium fredii|TrEMBL
MSPDINPFDPSAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHEATPTETLVAERLGHLREGIEENQQQLAEAAAH
HPH
>A0A315D4L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. Bal53|TrEMBL
MSGLKLPISLEFFPPKTPEGAEKLRGVREKLYSLKPEFCSVTYGAGGSTQEGTFATVGAI
QAEGVAAASHFSCIGATKASVRAELATLKTMGVQRLVALRGDLPSGYGAGGEFHYASDLV
SFIRAETGDDFHIEVAAYPEIHPQAKSPEADLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQAYGDDVESIKAFGL
DVVSDLCEQLINGGVPAIHFYTMNQSAATLAIMQRLNSLTY
>A0A1M5W558|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium grantii DSM 8605|TrEMBL
MGINEKFKEKNTVISFEIFPPKETSSLNTVYNTVDALAHLHPDYISVTYGAGGTSKNKTV
EISSIIKNKYNIDSLAHLTCISSCKNEIDEILFNLQENNINNVLALRGDIPHDVVFSIPN
PIEFNYSSDLISYVKSKGDFCVAAACYPEGHLDSPTKESDWENLQYKINLGTDFLISQLF
FENKYFYQLNDHLKEKGINTPLQAGIMPITNKAQINKIISLCGAKLPKRYENIINKFGDS
PQALQDAGIAYATEQIIDLLANGVDGIHIYTMNKPEIAKQIVRNISSVVNSINNIY
>A0A1Q7TTS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium 13_1_20CM_4_66_7|TrEMBL
MRTPRYEVLPTDNAADLVAAYVPRDITLTVTASPRRGMPRTIHLAVALAKLGYHAVPHLS
ARLIRDKVELGQILDALKTAGITEVFVVAGDAREPAGPFPDALSLLAALPPDHNLTEIGV
TGYPESHPFIHDDMTIQAMWDKRRLATYIVSNMSFDPEGVKRWVERVRNRGVELPIYIGM
AGVADPARLLRLSTKIGLADSARFLRGHPSWVARMFRPGGYEPARFAGALLPDIALPERR
IAGLHIYTFNEIEPTERWRREMLAQIR
>A0A074XXJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans EXF-150|TrEMBL
MPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVNVTWGAGG
STSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILALRGDPPRS
DEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQSHPEHQHA
TYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGLMPIQSYQ
ILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSGPKGFHFY
TLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSIANSAPQNRVV
IDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIPWSEEGLN
PETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVEFFCSHED
WTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIEAVSFRAW
AEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLLEA
>A0A2T3C477|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter woluwensis|TrEMBL
MESAEADMLSLHLEVIPTAGIVEAVRKAVPPSSSGSISITCLPKHGVDATLAVATELARD
GYQVVPHLAAKGLGSRERLRHVLEECADAGVTELFAVGGDAGTPAGPYADGEALLRGIAE
LGGGRFTLGVAGYPEGHPGIPDHVLLESLRRKQEHARRIVTQMCFSAERIGEYVTGLRRE
GVDLPVRAGVAGAVPTARLVSLAAKIGVGSSLRFLSGKTSLARNLLPGNRYAPEEMIGRL
GAQPGIDSVQLYTFNSLDGLPALGPGRASLA
>A6VT58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinomonas sp. (strain MWYL1)|TrEMBL
MTIIMPKFSLETTAKSINELFSVASILPPNTPVNIAFLGNESHEQRVNAAASIRALGLEP
TPIISSRRIKSKADLDYFLGELMAHSKNKRIMLVGGDPEVPEGPYESSLELLKSDILKTC
DVESVVIAGYPEGHPKIASHQLISSLKWKVDYLREHQFKVEITTQLAFCAANIIRWVQEV
RAMGIVEPIRIGVPCPTRVKTLRHFAKLFGVYISEASFVKYEMNTIYQQLDAKTDTLYLE
LVQQIESLAIENIYFHLYTLDGLSKNKLWIESHL
>A0A1M2Z6N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 65-79|TrEMBL
MSQFRFSRLPDIGGRVRVSFEFFPPKSDEMEARLWETVTRLQPLSPNFISVTYGAGGSTR
ERTARTVARILGETSLAPAAHLTCIDATRGEVDEVIREFAAMGVKRFVALRGDPAAGVGA
IYRPHPGGYSNAAELVAALGRAGDFDISVSAYPEKHPESSDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGILPIHNFRQVTNFAARCGAHMPAWLAERFA
GLDGDPQTHALIAAAVAAEQVLDLVERGVGDFHFYTLNRADLAFAICHMIGIRMPMQEQS
AQEAAA
>A0A2A6ZII4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MKDVREILKKRPLLFDGGMGTYYKAAPGQECEQANLLDPEGIQAVHRAYLAAGADAVKTN
TFGLPRMAAAQNPVWEALADEGWKLAVQAAAETGAAVFADIGPAPDTEAQPAAQLYIALA
DRFAALGAKNFLFETLSTDTGVTEAAQHIKKTVPDAFILVSFAVLPDGYTREGRHCAELV
RRMTESGVVDAVGLNCVSAPGAMRALVQRLGGTKLPLSVMPNAGYPVVTRTRVQYQGRPE
YFARELARIAAECSGVRILGGCCGTTPEHIVALRGALDALPDALPAAPAAEISTPAKPEV
EKDDAFLRKLNAGKKVIAIELDSPKDADLTGYLDGARRLQAAGAELLTIADCPIARARMD
SSLVACRVHRELGLNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDE
VKNVYQFNSRKLAQYIVSLAGEGREMPSPMTVFGALNLNARNFDVELRRAVEKMENGMSG
FLTQPVLSAQAVENLKKARETLGEKAKLLAGIMPVVSQRNAIFMENEINGIHVEQAIIDR
FAGLDRAQGEELGLEVSVQAALAAAPYADGFYLMTPFNRVALMERLIARLKEEVIAD
>A0A6G0F6X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SS1-1|TrEMBL
MALGTASIRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVRPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGDWVAHPRGLTYAAELVELIKASGDFCVGVAAFPAMHPRSADPETDVRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCDTPIIPEIMPIGSVRTLERIPSLTNASF
PDALRERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHPPQA
>A0A014DJE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_8|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGVRIGGAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKAFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELNVLEELWNSLWQVT
TGKEFSPEIVRFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKDKLIPTVSIETRGTSSWKNWYLGAEA
>A0A418B767|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces invadans|TrEMBL
MELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFKDEKLWLKI
GSHIQNEFKIDVLMHLTCHLPRDQLRDILKNVRAAGIRNILALRGDPPIGSERWKPVPGG
FHNAVELIRFIREEHGDWFCIAAAGYSEVHSEAWNNPNLPPSDQARQLDMIRLKEKQDAG
ADFIITQFFFDVDKLLQWIRDCRQLGISIPILPGYLPIQTHNSFLKFTNWCKTSVPPQVQ
EALVSIKNDDAAVKKYGIQLAVDTCKKLIANKLSLHFYTMNLARTVRAVLEGLHLIERER
GLPWGAPIMRNKDGSLEKSIEQVNRPVVQP
>A0A6I2IY78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium RIT714|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCITAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1Q9G1H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus licheniformis|TrEMBL
MGLLEDLQKQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIVQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSEALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTRAKEFIS
VQHERTEPGLNELAAEKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQKLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIYLH
>A0A564UD74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MTDIREYLAHKPLLFDGGMGTYYKAAPGADCEMANLTDPEGVKKVHAEYLAAGAQAIKTN
TFGLPRMAAAQMPGWEELAEAGWKLACDAAAEKDAAVFADLGPAPDTEAAPASSAYGLVA
QQFAALGAKNFLFETLSSDVGIVEAVKALRVAVPDAFVMASFAVLPDGYTREGLLFRDLL
RRMEQSGVVDAVGLNCVSAPGAMKKLVQGLGETRLPLSVMPNAGYPVVTRARVLYQGKPA
YFAREMGQIAAAGVRILGGCCGTTPAHIAALRAELDALPQRTEAAPAAKLSTGTAPAVEK
DDSFLRKLNAGEKVIAIELDSPRVADLSGYLEGARRLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGMCALPHLTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSAMTVLGALNLNARNFEVELRRAVEKLENGMSGFL
TQPVLSAQAVENLRKARQTLGERAKILAGIMPVVS
>W9GQ28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Intrasporangium chromatireducens Q5-1|TrEMBL
MAHGTASSMARAERFTRSIPAMIRSERPTISFEFFPPKDDAAESQLWQAIRHLEKLAPSF
VSVTYGAGGSTRDRTVRVTGRIAQETSLTAMAHLTCVGSSVTELRSVVGHYAAVGIRNIL
ALRGDPAGGLGTPWTAHAEGLDHADELVTLVRGLGSFTVGVAAFPDGHPESGDLAEDAAT
LIRKERAGAQFAITQMVFDVDNYLRLRDELARRGSRLPVVPSIMPITNARQVIRMAQLAG
QPMPSAVTERLDRHGEDAAGVRAEGIEIATESARRLLDEGAPGIHFITMNRSSAALEVHA
NLGVHATL
>A0A2D4XJ46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aequorivita sp|TrEMBL
MKVTEHIKNGNGKTQFSFEILPPLKGENIHSIFENIDPLMEFQPPYINVTYHREEYVFKE
LKNGLIEKKIVRKRPGTVGICAAIQNKYVVDAVPHILCGGFTKEETENFLIDLQFLGIDN
VMALRGDAVKSETYFTPEKNGHKYACDLVSQINDLNKGTYLDDELQHTFPTDFCVGVAGY
PEKHMEAPSSESDIHFLKKKIKNGAEYIVTQMFFDNEKYFKFVEKCRADGITVPIIPGLK
PIAVKSHLNLIPHRFKVDLPDALVMEVVKAKDNKAVRQIGIDWCVKQSKELVKAGVPFLH
YYSMGKSSNIKEIASQIF
>A0A0Q4F2R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Leaf15|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITRMCEQLLQGGAPGLHFYTLNQTEPSLAIWNNLKLPR
>A0A2R4WQT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium currus|TrEMBL
MIPTAFRPSRESRRPIRVSFEFFPPKTPEMEATLWSSIERLAPLGPSFVSVTYGAGGSTR
ERTHNTVARLVRETELKPAAHLTCVAATKGEVDDVVRAYHEAGVRHIVALRGDPAEGVGT
AYTAHPGGYERSCDLVAGIKRIGDFEVSVSAYPERHPEAGSLDQDLDALKAKVDCGADRA
ITQFFFDNDLFFRYLDRVQSRGIDIPIIPGILPVQNFKQAANFARRTGASVPDWLAARFE
GLEDDVSTRKLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRAAPAAAE
KAAA
>A0A2E5B2B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aequorivita sp|TrEMBL
MKVTEHIENGKGKTQFSFEILPPLKGENIHSIFENIDPLMEFKPPYINVTYHREEYVFKE
LKNGLIEKKIVRKRPGTVGICAAIQNKYDVDAVPHILCGGFTKEETENFLIDLQFLGIDN
VMALRGDAVKSETYFTPEKNGHKYACDLVSQINALNKGTYLDDELQHTFPTDFCVGVAGY
PEKHMEAPSSESDIHFLKKKIKNGAEYIVTQMFFDNEKYFKFVEKCRAEGITVPIIPGLK
PIAVKSHLNLIPHRFKVDLPDALVMEVVKAKDNKAVRQIGIDWCVKQSKELVKAGVPFLH
YYSMGKSSNIKEIASQVF
>A0A3T0RQY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrio sp. qaytius|TrEMBL
MKVIEHIDRAAGKSPLFSYEIVPPSRGSSAKDIVDVVEKLAVLQPPWIDVTSHSSSAFYQ
EKQDGTIQKRTLRKRPGMLGICGIIQNRFKIDTVAHMLCLGFSKEETEDALIELNFLGVE
NILALRGDAPNFSKPIRADRTMNILASDLVNQVRELRNGQFLDDLDNSSALNFCVGVAGY
PEKHFEAPSLKLDIQNLKKKVDAGADYVVTQMFFDNKKYFEFVGQCRDEGITVPIIPGLK
MLKSEKQLRSIPKNFYIDIPDELVDQVTTHPKQAAEHGKNWMKKQVQGLLDANVPYVHFY
VLNNVDAVTEVVKSFR
>C7QA95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)|TrEMBL
MALGLPSVRPDRAATVRELLTRGERSFSFEFFPPRDDAQEQQLWRALRRLEGYSPTFVSV
TYGAGGSTRMKTVETTERIAAETTLTPVGHLTAVDHSVAELRHVIGQYADAGVRNILALR
GDPPGDPLGDWAAHPEGLSYASELVDLVRESGEFCVGVAAFPEMHPRSPDWDTDVAHFVE
KCRRGADFAITQMFFLTDDYLRLRDRVAAAGCDVPILPGVMPVTNVAQIKRITGLTGQAF
PADLERSLMAVEGDKAAVRAVGVDWTTRMCERLLAEGVPGLHFITLNMSTATLEIYRNLG
LDRRHEQSSGMRLSA
>A0A4Q2ZMH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium|TrEMBL
MKITEHIARAEGKTLFSLEVIPPQKGIGINDLYTNIDPLMEFKPPFIDVTTSREEYVYLD
KGNGLVERRTTRMRPGTLGICAAIQYKYKVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
VMALRGDAMKGHNHFTPTDGGHERAIDLVRHMNDIGQGVYLSGEIPSNEDNRFCIGIAGY
PEKHLEAPSFGYDLQRLKEKVAAGADYIVTQMFFDNQKYFQFVKQARDMGITVPIIPGIK
PIATKNHLSMLPKTFKIDLPEELIGAVDAAKDNAAVKQVGVEWAIAQCKELLAAKVPVLH
FYSMGKSDNIRKVAEAIF
>A0A4Q3BMQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium|TrEMBL
MKVIDHINQATKPLVSFEILPPLKGKGIQSLYNHLDPLMEFKPSFINVTYHRSEHVFKKK
TDGTFEKVVVRKRPGTESICAAIMNKYNVDTVPHLICGGFGINETEDALINLNYLGIDNV
LVLRGDAAKNEAGFEPEPGGHKYALELLKQVTNLNSGVYLEEELKNTSKTKFCIGVAGYP
EKHFEAPNMDTDLQYLKQKVDAGADYIVTQMFFDNSKYFAFVNACRSIGIEVPIIPGLKP
IYTKKQLTVLPKVFHIDLPTDLSNEIVKCKDDADVEKVGTEWLLMQSKELYKAGVPVLHY
YTLGRPTLVANVVKEIL
>A0A0X8ETB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fragi|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETADHFHIEVAAYPEMHPQARNFEDDINNFVRKAHAGADSAITQYFFNADSYFR
FVERVRAAGVTIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIQSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3S1YI84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.09.1.1|TrEMBL
MNDMRQELIQTRGSATFAFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLATAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLEICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWLRVNER
>A0A2H6FBG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Abin07|TrEMBL
MKISEIFKKRDKGISFEFFPPKTEEGKKQLLTVAKELSTFDPMYASVTYGAGGTTQERTR
DVLYMLKEETGLTLMSHLTCIGATAESMDSLLNDYKEHGIDNILALRGDPPPDVPDFDPT
KGEFSYAVDLVKFIKKYDYFSISVAVYPEVHQEATSAEADLEYAKQKIDAGADFGISQMF
FDSRYFLDFLDRAYKKGINIPILPGIMPITDLNKIRKFASFCKATIPKEVEDRMSGILDK
PDEMQRVGIDLAVQQCEDLLDNGVKYLHFYTMNKSEAVSEIIGALKNKLN
>A0A351R9K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera mobilis|TrEMBL
MKPTAKKFDLSFEFFPPKTTEGMDKLREARAKLAKFNPEFFSVTFGAGGSTRDRTMDTVL
EIQREGYQAAPHISCISSSKSEIRELLQAYQAQGIKRLVTLRGDIPSGEVSAGDFKYASE
LVAFIREETGNHFSIEVAAYPEFHPEARTPAADLLNLKRKVDAGANSAITQYFYNADAYF
RFVDQCDALGINVPIVPGIMPIYNITQLARFSSVCGAEIPRWLKMRLEEYGDDMVSLRAF
GIDVVSELCETLLAWGVPSLHFYTLNQSNIISNIIENVQD
>A0A514CKG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Echinicola soli|TrEMBL
MKVTEHLNQAKKTLFSFEILPPLKGQSLNEMLDGISPLMDFNPPFIDVTYHREEFVYKKH
TNGLLEKVSTRKRPGTVGICAALMNRFKVDAVPHILCGGFDKEETENVLIDLNFIGVENV
LALRGDAPKSEGRFIPEEGGHSYSNELVKQIVGMNHGKYLHEETETGFQTDFCVGVAGYP
EKHFEAPSFKFDLKYLKAKVDAGAEYIVTQMFFDNQKYFEFVKNVREAGITVPIIPGLKP
ITTLRQITVLPSIFFLDLPDALMDELEKCKDNAAVRQVGIEWAIQQSKELVKFGVPGLHY
YTMSKASTVHKVASAVF
>A0A511DIH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sulfidoxydans NBRC 16205|TrEMBL
MTSLTALPRELPGRLADALRTGRFAVTAEIAPPRGADLAPVRRAAEHLRGWVDAVNVTDN
AGANVRMSSLAGSLALLGEGVDPVMQMTCRDRNRIALQSDLLSASALGVPNLVLMTGDRP
EQGDHPDAAAVFDLDSAALMSAARTLRDDGTLLSERTVDPAPRYLLGAVDSPGPSADRFA
QKVEGGAQFVQTQFVFDIAAFGGWLGQVRDLGLDTRCGVLAGVGPIRSLRALEFLSSIPG
VVIPEALERRLRGVPADKVAAEGVAACVETLRELRELPGVAGVHVMVVGDERGVPEILEA
AGLPRTS
>A0A7K7Z0V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thryothorus ludovicianus|TrEMBL
MVNETQHTHSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFEDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A0A2TJN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp. Tol-M|TrEMBL
MENKFKESLLDKNSLCVTWELVPGRGANEKAQETAIASAEQAAKGGRVHALTITDNPGGN
PAMLADYLGMEILKMGIEPLVHFTCKDKNRNQMESQLYALDRAKVRNLLVMTGDYPVSGF
QGRPKPVFDLDPSNTLQLITEMNKGLEVQGMKGPTYHAPSTFFAGAAVSPFKSTEAELMV
QYYKLKKKIESGAQFIVMQLGYDVRKCHEVLQFLKINNLDIPVMGNIYVLPYGAANLMNK
NKLPGCVVTDKLLAELNTEKSAPDKGVGQRMLRAAKLYAILKGMGVAGVHIGGHNLKYEQ
VEYILDKGEELSPDWQDLVKEFDYPQTNGFYYFEKDELTGLNTDRPTNRANLPLDAPTGA
MYTLLRGMHGLLFTPHKRLFPMMRGMYRAAEGKKKTEKGLHAIEHLVKVAMLDCKDCGDC
AILDLAYLCPMSQCPKNQRNGACGGSLDGWCEVYPQEKKCVWVRAYARLKKYGEEASLDV
PAVPPANWDFYQTSSWSNFFLGKDHSASRLGIKRPESKIKDGTV
>A0A7W5N641|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Tn43|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARHLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A7V8H7X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PEPV16|TrEMBL
MMIAPQSESREEAPLADLLSHYSIEVTSRDLQSLESMTATLPQGCEVFIAHLPKEDIGLL
VRAAAGLRDAGFMPIPHIVARNIRNRLELDTMLARLSEEAGVRHTLVLGGDRDDAAGAFG
SSLELIETGLFQAYGIDRIAIACYPEGHPRIAGAILDAALTAKIDAAARAGLDVLLVSQF
LFDPKPLLNFARRLRERGVTAPLSVGIAGPASRTKLLKYALRCGVGASLRALRERSEIAR
NVLSGETPEELLMEIAAARAAEPDLGISGVHFFTFGDPAQSIRWAEQQVDR
>A0A367IVM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus stolonifer|TrEMBL
MKVIEKIRQAEEEGRPFWSFEYFPPKTPQGVKNLYDRMERMKRYGPEFIDVTWGAGGTSA
DLTTQIVATAQSVYGLETMMHLTCTNMPVKQIDDALEAAKKCGCQNILALRGDPPQGQTN
WESCESGFEHAVDLVRYIRQKHGDYFCIAVAGHPEGHIDNPDKEDDLLRLKEKVDAGADI
VVTQLFFDVETFIDFYHKAQKIGIKVPILPGVFPIQNYNGLKRVISFNDNHVPQKIWDDL
EPIKDDDAAVKEYGINLTIEFIKRFREIGISGFHIYTFNLERSSRLVLERLELIAPVEHT
NPLPTPPVEMYLKSEKEITI
>A0A7C6R249|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotomaculum sp|TrEMBL
MKTESKLEKLLERGEFVVTAEIGPPKHASAEGIRHHAHMLKDYVDATNITDCQTAVVRLS
SIASAVHILDCGIEPIVQMTCRDRNRIAIQSDLLGAYSLGMRNLLCLSGDHQKFGSEPTA
KNVYDIDSIHLIYLMRRMRDEKLFFSGEPIKDHEPRFFIGAVANPFADPFEYRVDRLEKK
VEAGAEFIQTQCIYDMERFERFMEMVRERGIHERVHILAGVTPLKSWRAAKYLQTSVSGM
IVPDEIVERLKKAEDPKKEGVEICIEQIKHIRNIPGIHGVHIMAIAWEEVVPEIVERSGL
YPRPKVE
>A0A352T0W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MYIKELFNKKRFVFSFEIFPPKATSPIDTVYKTLEALSDLRPDYISVTYGAGGGSNQNKT
KEISSMIKNKYEIEALAHLTCISSTKDEIKQILRELKEEGVENILALRGDIPLEEDVKGD
FKHSSDLARFITEGSSFDLGGTCYPEGHYDSKNVEEDVINLKHKIDAGVTHLTSQLFYDN
NAFYEFMNLVHKHNINVPIQAGIMPITNKSQFDRIIALSGAKISDKYIKIMDRFQHDKDA
MADAGIACATEQIIDLMSNGVEGVHLYTMNNPYVARKVHSNLISMIHAINRE
>A0A847TDU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sp. Ak27|TrEMBL
MLKEKIHQPGSNLVFYSLTPPKATTQSEQVKIIAGKQVERLQGLSIDGLLLYDIQDESTR
TEKERTFAFQSTITPEDYSKNYLASLQVPKVIYKSIGNLDKAQFTNWLQANQHIDYAVFV
GASSHQQVEATNFSLQDAYDLRNQYAKSLVLGGVTIPERHTKKGDEHLRIFSKINQGCSF
FVSQCVYSLNDTKNLLSDYYYAGQDNDQSLSPLIFTLAPCGSLKTLQFMEWLGIEVPKWL
YNDLKHSKDILSSSIETCKNIAIEILNYTQAKNIPIGFNIESISIKKEEIEAANELLKDV
LQLAKGAGTSAGSLDLATHTDNLRLIS
>A0A6B0ZZK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. SB0666_bin_14|TrEMBL
MKSQVNPSAFQQALASGQPVVTAEISPPRGGSVDHVLAMAEQLRGRVHALNVTDGSRAVM
GMSSVAVCRLLLERHLEPVLQVGCRDRNRIALQADLLGAHALGLRNVLCLTGDPVKAGDQ
PKARPVFDYEAVRLLQDVKSLNRGLDALGRPLPDGPTALFPGCAADPQSPSWSGLKSRLQ
RKKEAGARFIQTQMVTDLAALRRFCRELAAPLGLPVLAGVFLLKSGKNARFINRMVPGAS
IPDAAIARLDGARTPRAEGLRMAAEQVAAALDVAQGVHIMAIKAESAIPQILDLAGVPPL
APPVVGGLGLRSLAAEPC
>E7C6F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Planctomycetales bacterium HF0770_03I01|TrEMBL
MEYQSSLHKKLSKGEFVYTAETTPPDAANQDVLLTKIMPLKGIADAVNVTDGPGAKVHMS
SLTAAIILAQNDIEPILQLTIRDRNRLALQGDLVGASALGVHNILCLTGDNPKNGDQPET
ACCKMINXPV
>A0A4U8YX30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoluna butyratoxydans|TrEMBL
MASLFKQALDSGKFVVTCEVAPPKGTNLEAMAHHVELLKDKVDAMNLTDHQSSVMRFPSL
GAALLVKEMGGEPILQMTCRDRNRLALQADLLFAHSRGINNVLCLTGDSVMLGDHKEAKG
VFDLDSSQLVMAVRMLESGKDLGGSELEGGISFCAGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVFDMEKFASFMGYARQFPVKVLAGIILLTSAPMARFMNANIAGVYVPPELVD
EMASAPKGGALKKGIEIAGRMIRQVRDEKVCDGVHIMAIGKEELVPEIMAAADIR
>D3AUL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi DSM 13479|TrEMBL
MKIKDILGQGKPTLSFEVFPPKTEDKYESVERAAAEIAKLKPAFMSVTYGAGGGTSRYTV
DIASTLHHEYQVTALAHVTCVSSTREKVHEVLEELKAAGIENILALRGDIPKDGPVASDY
RFASELIREIRAYGDFCIGAACYPEGHVESVSKTIDMDYLKQKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVVAGIMPVTNVKQIIRSCQLSGTYLPSRFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANGVDAIHVYSMNKPDVAAKIKENLS
>A0A1I3JVK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema bryantii|TrEMBL
MRIADILNSKKVTLSFEVFPPKKKEALESIKKTAVSLTELKPDFISVTFGAGGTTKGYTA
EIAEAIEENGTAALAHLTCVRSTTDALKNTIDDLKTRNIKNVLALRGDFPKDAVTGENIF
PSGYTHASDLVKLLKQEGMCVGGACYPEGHPESRSHEADIEQLKYKVEAGVDFLTTQMFF
DNDMLYSFLYRLQSAGIHVPVLAGIMPITNANQVSRMIDLSNAYIPRKLLAICDRFRDSP
EAMMQAGIAYATDQIIDLISNGVRGIHIYTMNKPEIARAIIHNVDDIIKAINN
>A0A3C1A6Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKIIDILKKDSLSISFEVFPPKFDTSFESVKSATEEIAKLSPSFMSVTYGAGGGTSKYTL
DIAKNIMEHYHVPTLAHLTCVSSTKDTVKRQIDDMKNAGIKNVMALRGDKLSDTDGGGIS
DYTHAIDLIRELKESGDDFCIGGACYPEVHPESTCQKEDIRFLKEKVDAGCEFLTTQMFF
DNNLLFNFLYKIREAGITVPIVAGIMPITNANQVERAIKLSGSFMPQRFKSIVDKFA
>U7G1I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. ES-1|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRAEIGELLDVYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEDVVTEMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISDREKIAF
>A0A1V0KGF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lactucae|TrEMBL
MLVEYLTSLHEIYPVKHEFAGFPAAMTLADRVHSDHDIAPLEASKSYPDSIDKVLHFSGK
ARDIQDFECFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHHYSQ
QILACVMPLTLARANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYVEQYRHLELKALEELWNSLWQVTSGKEFSPEISHFSR
QPSSKQLIKYRQLHVMHEAMFGSKIAKGLGRFIFKASFWENAVVAKVLIKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQT
EILKEKLIPTVQLETRGTSSWKNWYLATEA
>A0A7K8K8D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lophotis ruficrista|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6L8AQX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSHLSDSLALKSFTLTAELNPPKGTELDELYAAAETLKDWVAAFNLTDSAASRMAMAPLA
VARLLKDRGIESTLQIAGRDRNRLAIQADMLAAHALGVENIVCMTGDPPSGGDHPDAKPV
FDLGAEDILKAAVSLESGHDLADNALKGSPHFLRGAVVNVAVPDLGKEIGRMEGKIEAGA
EFFQTNAVYEPAGFEGFMKRVEGFKVPILAGIIMLKSAKQARYMTEKIPGVEVPDALIDE
LENAESRVAASVAMAGRIVQNVAPMCQGVHIMAIGWEHRIPAVMEAAGL
>A0A849WN04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionaceae bacterium|TrEMBL
MKVIEHILKTNAKNTGPEFSYEIVPPPRGRSVKDIIDITEKLSGLSPQWIDVTSHASSAY
YHENPDGTIHKKTYRKRPGTLGICGIIQNRFRIDTVAHILCQGFTKEETEDALIELNFLG
IHNVLALRGDTLNYHKEVSKNRSVNLFASDLVEQIKDLNQGRFIEDISNSAPLDFGIGVA
GYPEKHFEAANFKTDIQFLKKKVDAGADYIVTQMFFDNEKYFQFKKSCLEAGITIPIVPG
LKVIKNTTQLKTIPKTFSVDLPEVLVDEIIENPEHVEEIGSKWAYKQVEELVSHGEKNIH
FYIMNDANLVVDLVKKFKAL
>A0A6L7VL51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKRSDIAHLSFEFFPPKSVRGTHNLLRTARRLAEYEPDFYSVTHGAGGSVRDGTLETIRI
LRAEGFNAIPHITWRDDTRETMVSLLETYEALSVDQLVVLRGDIADQDDVKPTTFHYARE
LVELIRTCTGQKFRLNVACYPEVHPEAQSPQDDIRHLKDKVDAGADCCITQYFYDAETYK
EFVATCTKAGITQPIVPGIMPISNFPKLLAFSSKCGAKIPDWLRIKLTFMQGYQAKIREF
GADVVADLCRTLLQNKASGLHFYTLNLARPTQAILTRLIDE
>F7T0A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter insuavis AXX-A|TrEMBL
MKQALDEGRFACVLEVIPQQSPARLAALEPIVRRGHLAGWPLLPAFADRVGLHSDLSPLE
GAAALDDPSACLLHFSGKDRERADLLRQMAAMQARGLKQLLVLSGDRLPGHHPGQAPVRY
LESVPALQIAREHGPDWLLGAALNPFKYREEEGAAQYLKAQKKLLAGADFLTLQLGFDAA
KHLEAQDWMRAQGRGKPMLACVMQLTARRAAVLQDVPGIVITDAMRELLHREQQLSPAHA
SARSLERLALQIVGLQWMGYAGVHLSGVHTLDELLSLEQAIARQRDAVTSLADWVERWQA
SWRMPGMPEVCFAPDTDTWALGQSDVAATPGERLRYALLSTVHEQLFNRKGWLGSAFGWS
VTRPFWKTGVAAQALHAVERALKRPLVGCDTCGTCRLQDTLYVCPETCPKGLANGPCGGT
RLNRCEFGDRECVHSVKYRIAKSADQLPALAQTLIPGIEAGDRHRSSWPAWFKPEDPTPG
NDCQSLPKSG
>A0A250DVZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus stearothermophilus|TrEMBL
MGLLDELKQRILIADGAMGTLLYSHGVDRCFEELNLSNPDEIIHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGGAYVLGTIGGLRTLNKSVVPLDEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEEAAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRAASVS
VQADRPAPTPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIVKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDVSSFDLIRLISQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACSGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A6L7MUS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MADLSFEFFPPRTAAGSRTLVKAAKSLLEGRTAWCSVTYGAGGSTRDGTFETVSSLHEAG
IDIAPHLSWGRDREEDVLGLIRRYITMGVNRVVALRGDRPSGVGSGWQGHYAEDLVRLIR
QRVSAPIEISVAAYPEVHPDAPSAQADLEFLKRKLDAGADTCITQYFYNADAYFDFRDRC
EAAGISAPIVAGIMPITNYRNLVRFSDKCGAEIPRWLRHRLADLDGDDEALADLGADVVT
GLCQRLLEGDVPGIHFYTLNRAAPTLRVLGNLGP
>A0A523LG35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSKAPSISFEFFPPRTEKQQETFLRAREAFRRYVPEYYSVTFGAGGSTRDRTLETIIGIK
DQTDVAPAPHISCIGTEAESVRSLLEAYQRAGIGRLVVLRGDMPSGMAATGEFSHANELL
EFIRAETGDHFHIEVACYPEFHPQSENARRDLENFKRKIDAGANGAITQYFYNPDAYFRF
VDAARGIGVDVPITAGIMPITNFTQLARFSDGCGAEIPQWLRARLADYQNDLDSLRAFGL
DVVTELCRRVIEGGAPGIHFYTLNRARATSAICDNLGLGANQDLA
>A0A534FSN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPIRPGHTSPGRFERVLRAGQFAVTTELDPPDSADPEEVYRRARVFDG
YVDAINATDGSGANCHMSSLAVCALLTRVGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQALPVFDLDALTLLETARTLRDEHHFLSGRKITHAPRVLLGAAE
NPFADPIEWRAQRLAKKVAAGAQFIQTQFCFDVPLLRTFMNRVEDLGLLDKVFILVGVGP
LRSAKSAEWIRTRVPGVHIPDEVVKRLAGASDGALEGRRLCIDLIQEIRTLKGVHGVHVM
AYRQEETVAEIIQRSGVLGGRVPWNPGRDPPANTNRIASEPTPSAALEPARS
>A0A523MFP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MMPGLRRCIEQLYLEVIPVDGIEDDLLELPDGAYIGITCSPRKGLDATLDLVERLCGHDF
HIVPHIAARQVRDTLQLRDIVQRLTDQGVESVFVPGGDVSAPVGEFASALAMLRALADIG
HTFKPIGVAAHPEGHPTIDNQALLDALREKQAFATYFVTQMCFDADVLVRWVRMIRHAGV
VLPAWIGLPGVLNRARLLRTSLRIGVGDSVRFARRQMKLAGQLVKSPHYRPDDLVFALAP
HLGDETLKIDGFYLFSFNQVRATIAWRDEMLAGY
>A0A3C0I2Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSKKQALTTSCEFFPPRTDKAMLKLHQIREQLQVLQPAYFSVTFGAGGSTQEKTFETIVD
IQEQSDFDAAPHLSCIGSTRENILKLLQEYQAHGIRRIVALRGDQPSGWAGPLGKFRYAN
ELVEFIRAETGSHFHIEVAAYPECHPQAQSAKADLDFFKQKVQAGANSAITQYFYNADAY
FRFIDGCTQRGIDIPVVPGIMPISNFEQLARFSDTCGAEIPRWLRGNLKDLETDKAALQA
FGVDVVTTLCERLLAGGAPGLHFYTLNQAKLTLEIAKRLDLF
>A0A2E6BHI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDIKNPDARFSFEFFPPRTDAGMEKLMIVHQELAALRPDFFSVTYGAGGSTRDGTRQAVT
KISQAGSAVAPHLSFGGSSKEDILALLESYREMGINRLVALRGDIPSGTGAASQYFYANE
LIEFVREKTGDHFHIEVACYPEIHPQSDSYDSDIHFFKKKVDAGANSAITQYFYNPDAYF
YFVDNCEKAGIEIPIVPGIMPITNFTSLQRFSVNCGAEIPRWIRQRLQSYGDDVESIRAF
GAEVVLHLCEDLLAGGAPGLHFYSMNQTEPVRQIWQQLDLR
>A0A2S6MNM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. AC87j1|TrEMBL
MTDLTIPARADGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPPA
GIGTAYSSHPDGYQTSAALVAGIKKRHADIEVSVSAYPEKHPEARDFDDDIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A2D7IA02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTXKYLKLKDVLESGKFAITAEIPAPVSASSNEMEEKXKILKGSVHAINVTDNPGATAHM
SSLAGSAIVRNQGIDPILQITCRDRNRLAIQSXLMGASALGINNVLTLAGDPVKNGDQKD
AKAVFDINSKTILTIMDVMNNDGKTMSGRELQTKSSFFPGGAAIVHEPEDNWXPKVLSEK
ASFGARFIQTQFCYDVELVKRYIERIVDTGLSERMYFIIGIGPLRSEKSAKWMKDKLFGT
VMPDSIIKRMEGSNDQIQEGADICAELIESFREIEGVHGAHLMAPRNLSAIPETVKQSGI
TI
>A0A2E5RIS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIKMGKPSEAIAKQMREDLKKSYMEIIPVPGIEEKIGTLDPNMYLAVTCSPTKGVDETIQ
LTEKLIAQGFKVVPHIAAKCVSGKKHLETIVKKLDALGIEDIFVPGGDRPEPMGDFNNAH
DLLKALDKSGHNIKKIGIAAHPEGHPDVSDEVLMEALEEKKDLADFIVTQMCFDANILSD
WLVRINQKGIDLPVWVGLPGVIERGRLLRTSLRIGVGDSLRFLRKKSQVAAELMKSSTYN
PDKLIRDISEHNDISKVNFAGYHIFCFNQIETTEKWRTESISSLS
>A0A3C0TC02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNRHFSFEFSAPRSPEATEKLLQVHDRLQVCHPDFFSVTYGAGGSTKDGTRQAVITINEL
GSNVAPHLSFGGDPPEKIEQLLQDYQNAGIKRVVALRGDIPSGQMTKMTYANELVSFIRD
KTGDHFHIDVAAYPEIHPESASVESDLNFFKNKVDAGADGAITQYFYNPDAYFRYLDACT
ALGINIPIVPGIMPITNYQGIVRFSKNCGAEIPRWILKHLESYEDDPESLKAFGLDVVTT
LCHKLLEGGAPGLHFYTLNQSLPTIRIWRNLDL
>A0A2D9QIZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
EKASFGARFIQTQFCYDVELVKKYMQRIVETGLSEKLYFIIGIGPLRSDKSAKWMRDKLF
GTVMPDSIVTRMESARDQIQEGINICAELIESFQEIEGVHGAHLMAPRNLSAIPETVKRS
GISI
>A0A3D5XJW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGPQFNTPVSFEFFPPRDESGRDKLAAGTAEKLAALQPRYFSVTYGAGGSTKEGTKHTVT
DLTKRGWQAVPHLSVGAADQAEVLDLVNYYKTLGVKKILCLRGDQTESESQNPQYAEDLV
RLIRQHFGDHFEVVVGAYPEVHPDSSSSQEDLAFFKRKVDAGADVAITQYFYNIEAYEYF
VQQCQNLGIDIPIIPGVMPITNYASLCRFSEKAGADIPRWLDRAMAQHQDSEHDLSKFGV
EVVTRLCERLIDLGAPALHFYTLNRWGAATKICANLGLTAS
>A0A2E7XDN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAAQESFPRLFSFEFSAPKSEEAFEKIRRVHDRLSELNPHFFSVTYGAGGSTKDGTKRLV
LEINDSGSTAAPHLSFGGDAPEKIEALLNEYKDAGVTRLVALRGDMPSGMGASIKMTYAN
ELVTFIREKTGDHFHIEVAAYPEIHPDSRSVESNLHFFKAKIDAGANSAITQYFYNADSY
FRFVDSCEKIGVDIPVVPGIMPITNYRSLVRFSDICGAEIPRWIRKNLEDLQDDKDSLTA
FGDEVVARLCEQLLEGGAPGLHFYTMNQSLPIVRLWRNLGL
>A0A349UZG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MATDTAADTLPDLKSGSNLEKVLAAGHFAVTGELGPPKHMDTSVVDRKIGLLKGVVDAAN
VTDNQTGIVRLSSIATGIYMAQHGLEPVIQMTCRDRNRLAMQSDLMGAYIHGIRNVLCLS
GDHQSFGNHPGAKNVQDIDSMQLIRMLQEMRDKNQFQCGDEIKGGGPKLFIGG
>A0A2A4HZF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas ginsenosidimutans|TrEMBL
MTISVNQLEEARRALDAPLYADVGGDVDVSFEFSPPKTDKAEENLWQSIEALRPLSPRFL
SVTYGAGGSTRDRTHATVARIARDTDVPAAAHLTCVEATRAEIDAVADAYWQAGVRHIVA
LRGDPPAGASDYAPHPGGYENAAALVAGLQRLHPFEISVAGYPECHPSSTDRAADLDNLK
RKLDAGATRAITQFFFEPETFFRYRDAAAAAGIDAEIVPGIMPIGSFAGVMRMAAMCNTA
VPGWLGRLFEGLDDHPGARQLVAATVAAELCRKLYAGGVRQLHFYTMNKAELSYAICHLL
GVRAAPVQATAAAA
>A0A355AWI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
SSSFVVTSELTPPKGTDLDELFAKADLLRDLVTAFNLTESHAARMAMDPVAVGHLLIDRG
IEPIVQMTSRDKNRLAIQASILGAAALGVSNVVFMGGDPPKNGDHPDAKPVFDLFASQLL
EAACALNNGTDLSGNALKGTPQLTIGAVANPGASDLALEIDNMKRKADAGAEFFQTQAIY
DVAAFDRFMTKAKPERPVLAGIIPIKSVKMAQYMNDKIPGVDIPQDLIDKIDAAGDDKAK
VADISIVIASNTVRELRDMTRGVHVMAIGWEDKIPAILDRASA
>A0A534GR96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNAEPARTPIRVSFEFFPPADEAMGAMLWKSIERLAPLAPRFVSVTYGADGSTRERTHNV
VTRIQRETPLTGAPHLTCIGASREEILEIARGYWDEGIRHMVALRGDPPQGEGARRPNPR
GFRYASELVAALAGLAPFDISVAAYPEVHPEASSAAADLENLKRKIDAGATRAITQFFFD
TDAFLRFRDALAAAGVHAPLVPGILPITRFPQVLRFAKACGTSVPGRLHERFAGLDDDHE
TRRMIAASVAIEQVEALRRHGVSEFHFYTLNRAELTYAICHALGLRPHARSASAARQEAR
A
>A0A3R9SF65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lactucae|TrEMBL
MTRRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAEDLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHD
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A534BEE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGSANFTAHTPIRVSFEFFPPGDADMATTLWKSIERLAPLAPRFVSVTYGADGSTRERTH
SVVTRIQRETTLVGAPHLTCIGASRGEILDIARRYHDEGIRHVVALRGDLPQTQTRYQPH
PDGFAYASDLVAGLRAVADFDISVAAYPEVHPEAPSAGFDLDNLKRKVDAGASRAITQFF
YDIDVFLRFRDRCAAAGIRAPIVPGILPITRFPQVLRFAARCGASIPPWLKERFQGLDDD
HDTRRLIAASVAIEQVHALVRHGVREFHFYTLNRAELTYAICHALGIRPATQSPAAAAYQ
PGVPA
>A0A0C2YSD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp. AS07-7|TrEMBL
MFNTFCASLCSSAPFITVEITPPHGGSINKIIDNIKSLGLDKKVAGFTITDNPLAKLKMD
SILSAIKVQTELNKPVIATMSMRDKNKLSLQSTLLGANDFDIRCILALTGDPAKLSDQPE
VKGVLERDSTLLLSIIYKLNKGLDYSNKVLNPAPKPIYPFAVSNSYAKDTKHLLKKMIKK
LDYGARAIITQPVFGIENAKMLMHIFEEAKEISIRDTAKSAELILGQFPLISTKTANFIN
EQVPGIDVPKDIIDEMNLASMDGKEKEHDVGFAISKRIYDEIMALHPKVHLMTHNRFDLC
SELIG
>A0A369T450|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Korarchaeota archaeon NZ13-K|TrEMBL
MGLADFISIPECPFGRLTPSPLPLSVVARGLGVEAVPNYRVMDRSELGFLSEMMALQEVG
VRRVVLVRGDPPSIGSPTDLDPVRAIRLIKEHGIRIRVGVASQIKPSEALRAKIEAGADF
VVTQPIQSAEEIEGLIDFLGGIPVYAMVMPGIEELEASVLREMGITDVKRVDCRELMREL
GRIPKVAGVIISSPKGISRAIELLR
>A0A6C2ULX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontiella sulfatireligans|TrEMBL
MKNILELTKERPLIFDGAMGTMIYSKGVFINTCYEHLCITNPKLIAGIHQEYAEAGADVI
ETNSFGANRMKLQGHGLADQLEEINRASVRLAREAAGGDALVAGSVGPILKSGQVFLDNQ
ADELAETFREQLAILADEGVDFFMLETFTHIQEAQLAAQVAKTFGLPVFVSMTVGVSGET
EKGRKIEQIIQTLENDGNVDGIGLNCGVGPAAAYSNAERALPLTTKPMVVMANAGYPQEV
DGRMIYMASPEYFTEYAKRMIELGVRGVGGCCGTTPADIDTMAKSIKSMTGVKKHVAIAS
YTSQEAPKVDVIPLAEKCGFAAKLARGEKVTSVEITPPRSIDLKPMLAQCQTCKDAGIDA
INIPDGPRASARISPMVAALAVEREVGIETVLHYCCRDRNLIGMQSDLLGGYAGGLRNYL
IITGDPPKLGDYPDSTAVFDVDAVGLTQVVTNLNHGMDVGGNPINPPTGILIGVGANPCA
VEPERELQHYMNKINAGAEYAITQPIFDPEALLRFLDAAEAKGGSIPVVAGVWPLVSFRN
AEFLATEVPGVEVPDSILERMNHAKTKEDGRKLGIEIAREMCAAISDRVAGYQVSAPFGI
VDLALQVLE
>A0A6M9PUG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. LimPoW16|TrEMBL
MELSVEFFPPKTPEGESKLHLVRERLSESLKPAFYSVTFGAGGSTQSGTLKVVSDIHATG
AAVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
TETGDWFHIDVAAYPETHPQARSPATDIDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YELGVTQPVIAGIMPINNSTQLLRFSDACGAEIPRWIRLRLQSYGDDVASIRAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLSLDRLPRQIRQ
>A0A7Z2ZG32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. badrii|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQRH
GFEAAPHLSCVGGSRQEIRELLTLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VERLGVAVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGRKMQAYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1G0ZP04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_50_93|TrEMBL
MLAMTDSFVLKLLRKAFIMADTGKPLIQHLNSGFIVSCLTLEDCIRDAGGDLSRGADILN
LTRPDLITRLHGEFADAGAMLIATNTAAANTFCLRRIGIADKMREINIAGAKLAISGAGK
TAFIAGAIGPLGLTLDEDWDMETLRDAYVGQITALLEGGVHAIQFLSFVKLEELAFAVGE
ARQLAGKDFPILAQMIFSDNGLCETGENVEIAAARLVEAGADVVGVNGGQSISASVKAAE
RLAASAAGKLVAAHPNAGYPETAEGGRLIYMASPSYMGDTAIRLAKTGVRIVGGFSGTTP
EMVRAMVLALTTIRAAPVVSAPVKAQAPATAIPAKFKQGAFLESLTMTHPVIAEIDPPPN
LLSAGIVEDARVLVAAGAQAISMAENPLASLKMSNMAMAAIIRRELEVHTICHLTCRDHN
LLGTQSILMGMHALDIRAVLALTGDPLTASAGQGRSVFDLNSFLLTRLIAKMNTGLTNSG
ASLKGETDFSIGVAFNTGARNLENEVQRLHRKVDEGARFVMTQPVFDPGHARRVMDLIRM
PGLRVFLGFFPLVSARSALYLHNEVPGIRIPEPILAQLTSLPNKEDQEKAGLESSSNLLE
SLRTDLDGVYLISPHNRPRLLAPLIRQFRPG
>A0A1B1AFR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Viadribacter manganicus|TrEMBL
MSVEHLQDLIVDTSTRKRETRVSFEFFPPKSEKLEADLWASIRKLEPLAPSFVSVTYGAG
GSTRDRTHRTVARMVSETSLKPAAHLTTVAASRTEVDAVLRDYWRAGVRRIVALRGDPPG
GVGMPYLQHPNGYASAIELVEAASRIGAFDISVAVHPEKHPSSANFEHDIVNFKRKLAAG
ATRGISQFFFEADIFLRFRDRLARAGVYAPILPGIMPVTNVNGLRKMVEACGATLPRWMV
RLFEGLDDDPETRRLVTAVTTAQLCARLAAEGVEDFHFYTLNRADLTYSICRILGVRAKE
QTP
>A0A2E5FL29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacterales bacterium|TrEMBL
MKIIDTLKAGHQTVSFEFFPPKDDAGFDQLYKSIAALKPLKPSHVSVTYGAGGSTRQKTV
ELVKKIKHEIDIEALAHLTCVGADRAEIVSVLDELEASGIENVLALRGDPPHGEAQFTQH
KDGFGYASELAAFIKSRYSFCLAGACYPETHPEASDATTDLDNLLRKVDTGIDFLITQLF
FNNDDFLRFRDRATARGISIPILAGIMPILSLKQVKRFTNMCGATIPTDLLSKMEAVSDD
VDAVRQLGTYHAVEQCIELVEKEVAGLHFYTLNRSTATRAIYQQLKGSLLKPTNTN
>A0A3M7NM02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetothyriales sp. CBS 134916|TrEMBL
MADGHITTLISSLPPDQPFFSLEFFPPKTQAGFTNLRSRLSRMATALRPLFVSVTWGAGG
STASKSIELAEVCQCQLGLPTLLHLTCTNMKKTTIDEALAAQNHGDYFCIGCAGYPEGFP
PETQAHPRQQSVAHDLPYLADKIEAGAQFVVCQFTYDFQSYADYEDLVRAYSHHGKKVLQ
NVPILPGIMPIQNYSMLKRICKLTHVKVPTDLSAKLEKVKHDDDAVKKVGVEVLTDLVNG
IKDFPARDLDRGFHFYTLNLEKSCVSILDTAKLIPPLREVTPPGSSSDSDVFTDGPNGST
TIQHFSRRRASSTNAQAHNRVILSSPTPGTSPSTASAKSRHEAPDLGVGIPASDPTREQK
LLISKGHGSLGREATWDDFPNGRWGPAHSPAYGEIDGYGPTLKVGPGTARRLWGHPKSSN
DITQLFQRHVLGQLEAIPWSDEIDADETGAPGAGVLRAETRIIRDELLAIIGKKHYWTLA
SQPAVDGARSDDETFGWGPQREGFVFQKPFVEFFCLKDEWVKNLKPRLLRSPPEQVSWMK
TDAAGRYESSEINSHPASSAAKTAPDSGRGNAVTWGVFPGKEIVTPTFIESESFCAWSDE
AFAIWAEWRRCFPRGSDEEKFLERMRHDCVLINVVGHAYIGGARGGGRRLWEILLGN
>A0A2I1M811|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alloscardovia omnicolens|TrEMBL
MHKPQFSLEVFPPRRNGPVGSIYDTLDGLQGINPDFISVTYGTGKTADRTATARICHTVR
QEYNIPVVAHLTAQYLDKQQADEALDMFKQAGVSAVLALRGDAVEGREPTGVFKYASDLV
RYIREQCPDMKIFGACYPEVHPNSAGVVDELRHLKTKVDAGTSNLITQLFFDNDDFFRFV
EQARIAGIDVPIEAGIMPVTNAAQVRRMVTMCGARIPKELSAMLERWGDDPDAIRQAGVL
YASQQIADLVSRGVDGVHLYTMNHPCTTRRIWANVSALFKEV
>A0A1G9WYQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maricaulis salignorans|TrEMBL
MSAGKASGDGLSVSFEFFPPKTGAMEATLWESIRRLEPLDPAFVSVTYGAGGTTRERTHR
TVHRIVDETAIPPAAHLTCVSATRAEIDEVIRDYRDAGVRHIVALRGDPPEGIGEAYRPA
PGGYANAAELAAGIRAIGDFEISVGCYPEQHPESASLEHDLDLLKAKIDAGATRAITQFF
FEPETFLRFRDRARQAGITVPIVPGIMLQPNFKGLTRIAGLCNTHIPDRVHRHFDGLDED
AATRQLVTAHLAAQLCADLHEAGVDDFHFYTLNRAELALSTCHLLGVKPKLAATEAAA
>A0A5X7XLZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella derby|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A831RPS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sedimenticola thiotaurini|TrEMBL
MTTDLKNNLSLELFPPKTDAGMEKLRNSVHRLAALRPAYFSVTYGAGGSTQERTFETVEW
LRREGIETAPHLSCIGASREHIREILDHYRHQGIHRIVALRGDMPSGMGEAGDFPYANEL
VAFIRAETGDHFHIEVAAYPEFHPQAADAWTDLENFRRKVEAGADGAITQYFYNADAYFH
FLDDCRRLGVDIPVVPGIMPINNYTQLARFSDACGAEIPRWIRRRLQAYADDVESIRAFG
IEVVTELCQRLLDGGAPGLHFYTMNQAGPVLRICDNLGLGGRGTPE
>A0A1Q6ZMM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium 13_2_20CM_2_65_7|TrEMBL
MPTDFRSLIADGRVHVFDGAMGTMLYGKGFFLNVCYDELNLKQPRLVQEVHAEYVRAGAE
ILETNTFGANPLKLNSYGLADDTEKINRTAAELARAAAAGGGGRASVVGAIGPLGIRIEP
FGPTSQAEAQALFARQVQGLLAGGVDGFVLETFSDMQEMHAALNAVRAATDLPVACQMTI
GTDGLTYYGTDPETFTKQLTAWGADVIGVNCSVGPAGVLEAVEKMVKATDKPISAQPNAG
LPKDVGDRKIYLASPEYMASYARRMIEAGARFVGGCCGSTPEHIKKIRDYVASVVPRQPS
VVVSRAQVKAPEGVTATPLALKSGWGNKLARGELVTSVEIVPPKGVDPTPMLAQCRALKA
AGVDAVNVPDGPRAQSRMGVLPSALLIEREVGIETVIHYCCRDRNLLGMLSDIIGAHAAG
LRNILIITGDPPKMGPYPEATAVFDIDSIGLTNLVYRLNQGLDPGNNPLGGATKWAIGVG
VNPGAGDQDRELSRFAWKVDAGAEFAVTQPVFDVRQLEAFLKRIDQFKLPIVAGVWPLIS
LRNAEFLANEVPGVSVPEEVLQRMRKAQEQGKEAALAEGVAIAREMFTRVKQMVQGVQVS
APFGRVEVALQVFQ
>A0A5C7F3R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalicoccus halolimnae|TrEMBL
MDLKEHLKNGIIVGDGAMGTYLYQKGVQGCFEELNLSDPEQIKHIHELYINAGADIIQTN
TYAANSSKLARYQLGDCVKEINEKAVDIAREAAAGKAFVAATIGGVATMHQEKMPLEERL
ESLKEQTDVLLAADVDGFLLETFYDFEELKEILHYLRSKTEKPIIAQATLGDIGVLHTGM
HLQEALEQLEEIGADVAGVNCRMGPYHMLQSLEEVSLLEKAGISVYPNASLPNVRDGRFS
YQSNPTYFGDMTKALVEEGAVLIGGCCGTTPDHIREIRAAIERDNLTPVKQKQVRTKARH
PFVEAEPQLPKLTDLNEGEKSVIVELDPPKALSGVPSFMEGARALTDSGVNAVTLADNSL
ASARIDNLALGTKIKDAGARPLLHVACRDRNIIGLQSHLLGMHELGIRDILAITGDPAKV
GDFPGATSVYDMSSMDLIRLIKQLNQGQSFSGKDLGAKTSFTVGAAFNANARRLDREVQR
LEKKVEAGADYFMSQPVYSSERIEEIAEAVKHLPVPVYIGIMPLVSSRNAEFLHHEVPGI
KLTDEVREQMRSLSGDREASEKEGIRLATELIDTAMKHFSTIYLITPFLRYNITETLTRH
IRAQEKRTAGSRG
>A0A8G1KZZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania xiapuensis|TrEMBL
MSPTLDQMREAQRALEGPLFSGLPGDIEVSFEFFPPKTEKMGETLWHSVKTLEPLNPRFL
SVTYGAGGSTRERTHEAVRRIVSETGIPAAAHLTCVQATREEVDQVAREYWEEGVRHIVA
LRGDAPDGSGSYTPHPGGYENAADLIAGLKKIADFEISVAAYPEVHPDSPDRQADLDNLK
RKFDAGATRAITQFFFEPECFFDFRDKAVAAGIEGEIVPGIMPVMSFAAVQRMSGLCGTA
IPDWMEGLFEGLDERPEARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRPKA
>A0A376B4K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomycodes ludwigii|TrEMBL
MTQVSQTIRERFILNGDNPSVSLEFFPPKTEAGKQNLLARMGRMCTALNPLFITITWGAG
GTTSEKTLELASIAQNAFNVPVCLHLTCTNTAKSVIDHALQTAQKVGIRNILALRGDAPI
SDIYEKQQQDQEGGGGDEEIFNFNYAVDLVRYIKQVYGEYFCIGVAAYPEGHCDSEAEIN
SKSFLRDLPFLKQKIEAGADFVITQMFYDVDKFLSFEKVFREQISSAIPVIPGLMPINNF
MIFNRASKLSHASIPQAILDKFPIDLRSDDDVVKSIGVDILVDMVSRIYTGTNGRVKCFH
MYTLNLEKSIAQIVSRSPLLSQILEDEHNNTVTEMVIADDSDSTNKDDAIVEKKRRRQSS
SHSQENYRSILKKDLDTNIITSGQPSRKMLVSISQGTGTLGRDATWDEFPNGRFGDSRSP
AFGEIDGYGPSLKVSPQTAYKIWGYPNKLQDIVNCFVRYLQGSIPSLPWSDIGLSAETAL
IQEELIQLNERGYLTLSSQPSTNASSSTDKIFGWGPVGGHVYQKAFVEFFVGKHDWEQNL
KLKLNGLNQKTGNNIITYYMGDAEGNFETNMEPNSSSVVTWGVFPNSEVQQTTIVEEESF
KAWRDESFSIWLEWAKLFPRNSTSNNFLKHIYSKYCLVAIVYHDFTNFEGLWESLLDS
>A0A1F8PVE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_52_11|TrEMBL
MEQEYLADSRLERVLRSGGFAVTAELNPPDSANPQEVYDAAVVLSEVCDAINATDASGAN
CHMSSVAICALLTRAGYEPVYQVSCRDRNRIAIQGDLLGAAAMGVKNVLCLTGDDVTAGD
QPEAKRVFDLDSIQLLRMISIMRDKGMFLSGRKITTAPRFYLGAAINPFVPPYDWQAQRM
DKKIEAGANFIQTQYCFDVPRFSRFMQQVRDLGIDQKVCILVGVGPLRSDKAAEFMRTRV
PGVVIPDELVDRLRKTPKERQREEGKRICVEIIQQVREIDGVAGVHVMAYRQEELVAEII
EQAGLLPRPKQRYTLETDKLRRPRKFRRQRSA
>A0A2K1QMQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaceloma murrayae|TrEMBL
MHISPKLRQSAEEGRPTFSFEFFPPKTAQGVQNLYDRMDRMHDFGPTFIDVTWGAGGQLS
QLTTEMVKVAQSVYGLETCMHLTCTDMPRSKIDDALRDAYNAGCTNILALRGDPPREKEK
WEAASGGFRYAKDLVKYIKESYGDHFDIGVAGYPEGCDDHRDQELLVKHLKEKIDAGGTF
VVTQMFYDGDIFIDWVKKCRAAGIDVPIIPGIMPIHTHAAFLRRANWTQCHVPEHWTKAL
EPVKNDDAAVREVGKGLIAELCRKLIDNGIYHLHFYTMNLAQSSRMVLEELNILPCAESP
VEKPLPWRQSLGLKRREENVRPIFWRNRNRSYIARTQEWDEFPNGRWGDSRSPAYGELDA
YGIGLKGTNEQNRKVWGSPKKLRDIAELFARYIEGKVESLPWSESPITGEADVLKTDLAN
LNRRGLLTVNSQPPIDGAKSSHPVYGWGPRNGYVYQKAYLEVFVSPELIAELITRIERDP
DVTYFAVNKDGDLKTNSPSDSGPNALTWGVFPGKEIVQPTIVEAVSFMAWKDEFYKLGGD
WSKCYDNDDPARYLIGEMMETWYLVNIVHNDFRRERTIFPFFNGLEVPDLDKPAVVGLHL
NGDAQHERTDSARVNGHNSANGKENSKPDTNGDSAVGLGIKPKN
>T0SSR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella parvula HSIVP1|TrEMBL
MTLREKHQQGQFTITVELDPPKSSSAEKTFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDAPTNFYIGATGNPGAPDLEIERQKLAAKIQNGA
HFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
MEKGGKEAGTEIAIETLEQIKKMAAGVHIMPLNDIDTTLYIIDHV
>A0A5R2NHZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2D.F.Ca.ET.145.01.1.1|TrEMBL
MNQFRFSRRPDIGEKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVIREFVDFGVTRFVALRGDPAAGVGT
IYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLGNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
AGSAAA
>A0A0R2PQG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR86 cluster bacterium BACL1 MAG-120920-bin57|TrEMBL
MKISYEFYPPKDLNYQKIIEEYSLLSNFGPRFISITYGALGSSQEKSVGLIKAFKESVDV
EVVAHLTLVGKSKQELSFIVDEFSSMGVTKIVALRGDVAEGSFIAHQDGFQNTAEFVDFL
AKKKMEVFVSAYPEPHPDSKGFDFDVRLLKDKTLAGSRQSISQFCFSMHEYQRLVDAIKD
QNIQNDLTAGIMPIYNIASLCSMAERCGIKIPPEIIGQFSEDPQKNEQASIKICIQQLED
LQAMGINNFHFYTLNQSSLLKKIFNEIGF
>A0A1Q7RST1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_40CM_2_56_11|TrEMBL
MARNPLRECLQSRRFCHVVEIVASRISREARLLEVASQLATTPGVVAGSITSYAGGAPGQ
DPVRVGTAARARGLTPNIHVTCVSKDRQELRHYLETIAGLGLENVFALTGDYPKDANAVF
DLDSVQLITLMNELRRQGLPFWIAAAVSPFKYTEPDCAYQYLKLEKKFTAGADYAITQLG
FDVRKFRELRRYLDERNIQNPVLGNVYVLGLKSAEKMSKGEPPGCWVAPELVEKIRDEVK
AKDKGEAARLERAARMIAILRGLGYAGAYIGGTHNAEHLRWIIERGQILAPRWKELADEF
TYAPKSAFYMFEPGPAAPRKLRGLSDRAVNALWHLLSPTQIPRGSILEKWARAMFAWIDR
RPTMSRFLERAEFAIKSPAFGCETCGNCVLPDMQYVCPQTCPKQLRNGPCGGTNNGQCEV
IPERSCVWVRVYDRAKHAGEIPLLRIYIPPPDRSLKGTSSWINYFLQRDSRPGSPETSAL
SLRPQATKNPRPTWR
>A9C182|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia acidovorans (strain DSM 14801 / SPH-1)|TrEMBL
MSFPISFEFFPTKTPEGAAKHVQVRKNLYARKPQFCSVTYGAGGSTQAGTFNMVRDIQSE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPHSDLEAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A2L1IGD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SWI36|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARTHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQVARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQASPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALETRIEYWQTQVQSLEQWAPA
WHASWQMPGLPAVTFHPPQAGWRLDESRVDASFKEKARYHLMHGMHALLFSRRNSLSKAF
GWAVRQPLWGTRVGAHVLHTLERSVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A2M7L2C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium CG_4_8_14_3_um_filter_66_20|TrEMBL
MQNLIERMKQSPVVFDGAMGTMIYDRGVFVNACYDELCLSKPDLIAEIHRDYVAAGVDVL
ETNTFGANRFKLRPHGLGEKVEQLNRAAVRLARQAGGDGVYVVGSVGPCTGSDQALPAVQ
AEAVREAFAEQIGALVGEGADAVLLETFAETEELRLALDAAAGCDCLVIASFTVNQFGQT
AMGTEADVIVAELERDDRVDAIGTNCGTGPAGAFDTLERILPLTSKPVIVMSNAGLPKEV
NGRMLYLTSPEYFTKYARKFIELGVRGVGGCCGTTPEHIRQMAKAIRALTGVKQHVIVTP
TVRAATQVQVIPAAEKSRFARKLLSGEKGTSIELLPPRSIDMSSLIAKARQCAEGGADCV
NIPDGPRASTRISPMIAALTIEREAGIEPILHYCCRDRNLIGMQGDLLGGYAAGLRNFLL
ITGDPPKLGDYPDATGVFDVDAIGLAQAVANLNSGVDIGGNPVDPPTGIFLGVAANPSAV
DLEREVERYFRKLDAGAEFAITQPIFDTQALYRFLDRVEGYGRSIPVVAGVWPLTSFRNA
EFMNNEVPGVVVTEDILERMAKCETKEEGAQAGVEIARETMDEIAGRVAGYQVSAPFGRV
ELALAALGLA
>F8JFY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp. (strain MC1)|TrEMBL
MTRLTTSLAGTQPNEDGSSLASEKPLMGNISIELLPEHVATFHPTAANLKPGSFVFLTHI
GGKSLAAQAGAAARIKAMGYEPVCHLGARNFTSRDEYANHLSALSDAGVTTVLMIGGNSS
DSVPPMHSAMELLSHSIVPRTGIKRIFFAGHPEGHPSIPPEILVPTLLEKINVARELSLV
PEIVTQFAFDGAAMAAWGAGLRKAGIDVPIRFGVAGVTSLPKLIKFAMLCGVGASLKGLS
RQGGSILKAMRDQDPGDVISQLRIGTEAYALKGIDLHFFPFGGWEKTLNWIAASSGAH
>A0A624BC22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella montevideo|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A538T569|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium|TrEMBL
MKHPFLKRLEEGVVLADGAMGTLLYERGIPFDRSFDLLNLQEPALVQSIHRDYIRAGAEL
IETNTFGASRVRLAAHGAGEDARRVNRAGAQLARNAREEVGEAVFVAGAIGPLGKPVAPL
GTIPKEEALAAYVEQVEGLVEGGVDLLIIETQTDLEEMKLAIQAVRRVTDLPLVAEMTFT
EDGRTLYGAYPEDVVRATQSLGVNVLGANCSVGPQKILEIVQRLRRRTELPISVMPNAGL
PQFVGGRFLYLASPDYFADYAIQLEAAGAHLIGGCCGTTPAHIRRMREALARPGAGAAEA
AALDRASAPPPPPPAPHVVLEEPAAGDPASRSLLARKLSNHEFVVSVEVDPPRGARPKKM
IEGAQFLKSSGVDVINVADSPMARVRMSSLALASMISHQVGVETILHFTCRDRNLMGIQS
DLMGAHALGIRNILALTGDPPRIGDYPNATAVFDVDSVGLIRILKQLNAGTDLAGNSIGE
PTRFLIGCAVNPASEDIHAELERFSKKVEAGAEFTMTQPLYELEPLTRFLEAVGKKRVPV
LLGLLPLQSHRHAEFLHNEVPGINIPEHAREAMRNAGEKGIEVGVEMCRALLLKAKDMVE
GAYLMPSFGRYEVVARVAEVVRSAPKAASPA
>A0A852W914|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia antarctica|TrEMBL
MDLRRRISDRHGEFLLFAVTPPRKSTSPQRVEEIADATIARLRPLGLDGLVLYDIDDESD
RNAEQRPFPFVSTLDPADYLARYLTTWTAPAVIYRVVGKYPEAELRPWLDAQDPEQVLSV
FVGASSRDKEVAMSLKQAHALRAQTSPELAVGGVAIPERHTRSADEHLRLLAKQDAGCRF
FITQVVYDVNAAKNVVSDYRLECIARGVDPVPIVFTFTVVGSTKTLEFLSWLGVEVPRWI
QNDLIHSDDVLSTSYEQSLSCALDLITFCRRLGVPFGLNIESVSSRRAEIEQAVQLAARL
GQELHRPRR
>A0A319B7Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus lacticoffeatus (strain CBS 101883)|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVEQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDTSSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A0K6H097|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chelatococcus sambhunathii|TrEMBL
MSHAPFRPSRRGACPVRVSFEFFPPKTAEMEATLWASIERLAPLGPHFVSVTYGAGGSTR
ERTHATVKRIVEETPLAPAAHLTCVSATRAEVDDVVRAYWAAGVRHIVALRGDPAEGIGA
VYTPHPGGYDGSPELVAGIRAVADFEVSVSAYPEKHPESVSIDADIELLKRKVDAGATRA
ITQFFFDNDVYFRYLEKVRARGIDIPIVPGILPVQNFKQAANFAARAGASIPAWLAGRFD
GLDQDVETRRLIAAAVAAEQVIDLVDRGVTDLHFYTMNRADLVYAICHLLGLRAGTAVAE
PVAAAAVA
>A0A516IZI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium cosmicum|TrEMBL
MSGAMTDPTTPAHAGQDGHLAVQRPAISFEFFPPKTEDMERNLWDTINRLAPLDPKFVSV
TYGAGGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALR
GDPAGGIGTPYSSHPDGYQSSADLVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLK
AKVDSGATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARAFVTRAGTS
VPDWFAAKFDGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISHLL
GIRAKSAQKAA
>A0A446TKT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Triticum turgidum subsp. durum|TrEMBL
MKVIEKIQEAAANGRTVFSFEYFPPKTEEGVENLFERMDRMVAHGPNFCDITWGAGGSTA
DVTLDIANRMQNMVCVETMMHLTCTNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFSCALDLVEHIKAKYGDYFGITVAGYPEAHPEVILGEEGATEEAYSKDLAYLK
RKVDAGADVIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNL
GLIEESKLSRTLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWGDSRNP
SYGALNDHQFTRPRGRGKKLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPE
TTIIDDQLVKINSKGFLTINSQPAVNAEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLG
QLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWSRGWACLFPEGDSSRELLEQIQKSYYLVSLVDNDYISGDLFAAFKEI
>A0A3M2HV42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas zhaodongensis|TrEMBL
MSQPRSHSFSFEFFPTKTDAGHEKLMATARRLAEYNPDFFSCTYGAGGSTRDRTLNTVLQ
LDGDVKVSTAPHLSCVGDGKQELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRRMGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMESIQA
FGNQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWDNLKLVR
>A0A2E2UN41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trueperaceae bacterium|TrEMBL
MRVSVELVPRNKIDLEGQLGQVQNYFPSVDTINVPDIHRFEMRSWEACTIARKYVPHVIP
HIRAMDVNPEAPLAMANELQATGVTEVVVISGDMPAEMSQTVYGTSTLTVIKKFRDELPG
VRIYGALDPYRQGFQAEIEYAHQKLEAGACGLFTQPFFDLRLLDIYSELLSGVQIFWGFT
TITSQRSMRYWQARNRAIFPVDFRPNLEWSRRLAGEAFSLLQSRNGNAYFMPIGIDVADY
LAGII
>A0A521F0Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliifodinibius sediminis|TrEMBL
MKVIEHYDRAEEPLISFEIIPPKRGKSVKKVFDSLDQVMKYNPPFIDVTYHAAESHYEEL
SDGTIKRHIKRKRPGTIGLCAAILHKYGVDPVPHLICEGFTKEETEDALIELNYLGIDNV
LTIRGDAADESVPRYKNGTFNKYAVDLVKQVKNMNRGEYLEDIVNAQHTDFCVGVAGYPE
KHFEAPNLDFDIQMLKNKVEKGGDYIVTQMFFDNEAYFRFVRKCRDAGIECPIVPGLKVL
TRERHLNWLPKYFHLNIPEGLSEEVQTNPTHAREIGIEWAAQQCTELLESGAPGIHFYIM
GDPSPALSVIDKLPLGHGVKK
>A0A1E4VAF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. DNP9|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A0R2R4I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium BACL11 MAG-121001-bin54|TrEMBL
MKVTEHIKNAKQTLFSFEILPPLKGTSIQSIYDSLDPLMDFNPPFIDVTYHREEYVYKQR
TDGLLERKSVRKRPGTVGICAAIMNKYNVDTVPHIICGGFSQEETENALIDLDFLGIDNV
LLLRGDPIKHETYFTSEQGGHTYACELTQQVFNMNKGIYLDEELKNSAPTNFCVGVAGYP
EKHFEAPNMRSDIHFLKKKVEAGADYIVTQMFFDNQKYFDFVNLCRENGITIPIIPGLKP
ISTTKQLTLLPQRFNLNVPNPLVDAVIKCKNNEDIRQVGVEWAIQQTKELIEFGAPCIHF
YTMGKSDNVVEIVANFA
>A0A502YPS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-6-6|TrEMBL
MIARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDIVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDDVTETQVDMVK
TAH
>A0A546XS46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MIIKRIKHKLPDISASSIIPASIEASPAQVLGPASLAGLFPQAVRVYLTDTGAASQERLV
DAARHLRDLGYEPVPHLAARRIPSRVEFEEQVKRLAGEAGVSDVLVVGGGVDRPAGPFAS
SMDMLSTGIFDRYGISRIAIAGHPEGSPDFSEETALAAMRLKRDFAERSDATMRIVTQFG
FDPARFIAWAEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLRKNALSLTT
LAKGHSPESIVGPIEQHWQANPQGAIRQIHVFPFGGLQASSDWLVKRGSWQTGNTSRSAP
PDSLAV
>E8U946|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus maricopensis (strain DSM 21211 / LMG 22137 / NRRL B-23946 / LB-34)|TrEMBL
MRVSVELVPRDAASLAEELAQVRAHLPGVNTINIPDLSRFPLRSWEGCAHAKGCFGDSGL
QHVIPHVRAIDVNPNRPLAIAAYLAEHGIDEVLVVTGDAPADMSRPIYNNDALGVIRKFR
EELPHVRVYAGLDPYRQGFTREREYAQRKLDAGACGFFTQPFFDVRLMDVYADLMDGVDV
FWGVTTVTSTRSLRYWETRNHAVFPRGFQPTMDWNRQLARDAFAFARERGAHIYFMPVRA
DVRAYLEGIV
>A0A1Q6HYZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. merdae-related_45_40|TrEMBL
MKVIDLINSSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSFQKINIRKRPGSVAIASAIQNKYGITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQKTDIYHEHATDLQQQVNDFNKGIAIDGSAFEANETPFSYGMACYPE
KHEEAPNMDSDIFYLKEKVKNGADYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCKTDDEAKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVYKVAKEVY
>R8Y6N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus ANC 3811|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLRIVHQELQLLNPDFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDAYFYFI
ERLEKTGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VIVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A128F0G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grimontia marina|TrEMBL
MGYSHASHLDALNQNLSDLNGDINVSFEFFPPSSEAMEQTLWASVQRLKTLKPKFVSVTY
GANSGERDRTHGIVKSIKQETGIEAAPHLTCIDASRDELREIARDYWNSGIRHIVALRGD
LPEKSQKPDMYAADLVELLKGEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIIPGILPVSNFKQASKFANMTNVRIPAWMHKQYE
GLEDDAVTRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPTV
>A0A1F8RKU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_63_12|TrEMBL
MRSGSRLERVLRSGRFAVTAELNPPDSADPQAVYDRALVLASVCDAINATDASGANVHMS
SVSVCALLTRAGYEPVMQVSCRDKNRIAIQGDLLGAAAMGVRNVLCLTGDGVQAGDQPEA
KPVFDLDSMTLLRTACTLRDNGMFLSGRKLDVPPKLFLGAAENPFAPPYDFRPHRLAKKV
EAGADFIQTQYCFDVPRLREFMAKVNDLGLHERVFILIGVGPLRSAKTAEWMRSQVPGVH
IPDAVVERLKKGKKDEGKRLCVEIIQQVHETPGVSGVHVMAYRQEELVAEIIEEAGLLPR
RRVRAETPADKKETVAK
>A0A1M6JLR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dethiosulfatibacter aminovorans DSM 17477|TrEMBL
MILDYLKKNILLTDGAMGTYYAELTGDYHTTCELANLQNPDIIREIHRQYLDAGAMLIRT
NTFAANRSKLDVSLETLKDIIQKGYAIAEEAAKESNAFVAGSIGPIVAVDIDQNENDILE
EYKIIADALLSAGARIILFETFSSINYLKSVSRYIKEKDDSITVMAHFAVMPDGYTREGI
SINHILDNVQEIESIDIHGFNCGSGPTHLHRMIRKLDFSGDPISVLPNAGYPEIINERTV
YVNNPDYFADKMMDIKNLGVKIIGGCCGTTPEHIRVLAQKLAEGNGKETRQEPARTVHKE
KHTKLQNTFQEKLSKGEFVFAVELDPPFDTDIAKIMEGARLCSKENIDLITIADSPMSKV
RVDSIAIACKIKREVGIDTMPHVCCRDKNVIALRSGLLAAHVEGIRNILAVTGDPVSADT
LASVKGVFNLNSYKFMSLISQMNIEVFGEDPLSIGGALNLNLANKDKEVSRMMKKAENGA
TFFLTQPIYEDETIDYLKTLKDRNVKILGGILPIVSYRNARFLNNELPGVHVPAEYVNRF
NPDMTRQEAEETGIQMAVELAKKLKPHVDGIYFMTPFNRVSMIVEIIKRMG
>A0A6N7HZ71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MSDFDTELGRRVLVCDGAMGTMLHAAGNSLDRALPELNLSNAELVTTVHQSYVSAGVDVI
LTNTFGASRLRLADHGYSGDVREINLAGARIARQVREAADRQVFVGGSISPAVTAGQRQG
IGVNERVEAIAEQVDALAEGGVDVLVFETFGYLDELVEAISTAAGRTDLPIIAQATITGD
GGTLGGETPHDLATAVSALPVVALGANCTVGPQGMLAVVEELRRFTSLPIIAQPNAGLPR
RVHGRRFEYNIDGDYFARYARRYTESGAMLIGGCCGTTPTHLGAAVSGVADLRPRERRET
GTRAAPASGQSELADRLVRRDFVTAAAITPPSGGGADEAAEVVAGLHRRGIDLFTVAARP
STRAQLTAISLALHIQQNVEVATIPTVTTWDTTIMTLQANLLGAHALGVRTVICETGNPP
LRGDYPNADGIWEVDSVGLIELLAGLNSGRDCNGLSLATKTSFHIGARFNPGADDIDAEI
ARTRDKLRAGADFLITRPVYELDTFRRMTVDLSEEDVPVLLAISPLGSFAEAEYLAYEVP
DVTIPAATLRAMERAGAGAADVGLELATELLGQARGLARGVVLGVPDGEPERVERLLRAV
>A0A2A4YLD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillales bacterium|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQVVRDQLAGVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTRAEIAELLDVYKENGINRIVALRGDMPSGMGASGEMRYAN
ELVAFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVEAGANSAITQYFFNPESY
FYFIDRLEKLGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTVSIKK
FGEEVITEMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISGREKIAF
>A0A0P9NRR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas congelans|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFT
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A2V4IBG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas soli|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALLAEYQAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGNHFHLEVAAYPEMHPQARNFESDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2G2DNQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotalea sp|TrEMBL
MKTESNLEKILAAGHLAVTSECGPPRGCKPDEVIKKSNYLKGIVDAVNVTDNQTAMVRMS
SLAASVIVKQQGLNPLFQITCRDRNRLAMQADIIGAYSLGIDTMLCLSGDHTKFGDHPQA
MNVHDIDSIQMIQMVRDMRDKSIFQGGAELKGAPKMFIGAAANPFADPFELRVMRLAKKI
AAGADFIQTQCIFNVDKFEKWMEGVRKLGLHKKCYILAGVTPCKSLGAAKYMSKRVPGMD
VPQEVIDRMSSVPKDKQAEEGVAICVETIKRLKKVEGVAGFHIMAIEWEEKVEEICERAG
LLPRPQV
>A0A0I9XN73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella fujikuroi|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIHDIALLFVRYLQNEIESLPWSEAPLTTEADEIRDELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYNMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKGLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A086CZI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium MFB021|TrEMBL
MNTHLPLGISFEFFPPNTVAGREKLDATRDALSARSPRFFSVTYGAGGSTQARTLDTVAA
LRQGGVATAPHLSCVGSEKAAIRELLGRYRESGIDSLVALRGDLPSGMGGAGELRYANEL
VEFVRAETGDHFNIAVAAYPEVHPQALSAERDLENFARKMKAGADFAITQYFFNADAYFH
FVDRARALGVEAPIVPGIMPITNYSKLARFSETCGADIPRWVRKQLEAYGDDQQSIQAFG
TEMVSRLCQRLLDGGAPGLHFYTLNQAAPSLRILDNLA
>A0A2D1U8B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter ginsengisoli|TrEMBL
MKIVDHINNAKGKTLFSFELLPPVKGKSIEEIYKAIDPLMEFNPPFIDVTYHREDYIYKQ
HSNGLLEKVSYRKRPGTVAICAAIMNRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADSSFIPTPGGHAFATDLLQQVTDMNSGKYLHEDHSAFKTDFCIGVAGYP
EKHFEAPNLKTDFKYLKQKVDMGAEFIVTQMFFDNNKYVNFVQQCRENGINVPIIPGLKP
ITSSKQLISLPKVFHIDLPEELTEAVQACKDEKQVKEVGIEWMIQQCKELIQVGAPVLHF
YTMSNPEPTKKIAQAIF
>A0A1H9SZ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas soli|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALLAEYQAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGNHFHLEVAAYPEMHPQARNFESDLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITHMCEQLLQGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A4Q1QVP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sioyaensis|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWVKHPDGVAYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVD
KCRAGADFAITQMFFYPEDYFRLRDRVTAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A7I9WMG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium murale|TrEMBL
MSNVGSRTLSVVDRIAEVGRDRVPFSVEFYPPRDAAAEARLWRAARTFEPMGPAFVSVTY
GAGGSTRDRTVRVVGELAEATTLLPVAHLTAVGHSVAELRAMVGAYADRGIHNVLVLRGD
PQGGVHDEWVKHPDGLEYAVEMVDLVRRLGDFHVGVASFPEGHPRAGGLEQDTANLVGKL
RAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPLIPGIMPITSLRVLRRQCELAGSQ
IPVALLDRLTAAAGTGAEEDRDEVRKVGIELATEMSARLIAEGAPCLHFCTLNFARATGE
VLANLGMMARV
>A0A8J6P4G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfatibia vada|TrEMBL
MQLKRKFETGEFAILAEMEPPKGVDVSTMVTNARRVKGNVDAFVVPEMSNAVMRMSSLGG
AVILQKEGMEAVSQLNCRDRNRIAIQADLLAAYGCGITSVMAVTGEEPGYGDHHQARSVY
DIDLLELLRATQKLQEGKDMAGIELAGAPRFLVGSTVDAGAKGKSPELVVEEMKQKVDAG
ATFFVTPPLFDLAAIQPFIKRVDLGKIKIIPTVLLLKSLGMARYIQRNVEHVDIPDALIT
RIQKSPDKVRECLRIASEMAKTLQQEGFGGVLLATIGWEHKLPEIMERM
>A0A7G2SPY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MTSSVDSVPAPAPFSFELYPPRTAASEAALHETIARLAEVGPRFISVTYGAGGSTGGRSL
EVLRHIRATTDVEPLAHLTCVGNTYAGANRLIREFLDAGIRSFLALRGDPPAGTSEDDVY
LGDLESAAQLVQLIDRVQAERAPYQESGIPGMPGAARVDPRPRVDIAVAAFPNGHPRSRH
PREHIDALLAKQAAGATLAITQLFFHADDYVWFVDRARAAGVTIPILPGIMPITGPARLR
RVLQLTGEEIPADLAIALEVEPTAEGQREIGIAHAARLAEEVLAGGAPGVHLYAFNNHDT
VLSVLREAGILTAGASGPASTPVKESRR
>M7TPI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryotinia fuckeliana (strain BcDW1)|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRALDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDGFEQKLRDHPSGAFKDIPIIPGMMPIQSYQMI
KRTTKLSHAKLPSTIITRLDAVRGDDEMVKKVGVDILSEMVEHLKSTKSQYSGPRGFHFY
TLNLEKAVSFILERTELIPDAETVAALEPEYVPTIPDIADLLSIHSGSHKRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGPKNGFVFQKAFVELFI
PVADWKTLHAKLTSPDLCDTVSFYASNAKGDFISSDEAVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSQTRKIIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLS
>A0A386XD96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ethanoligenens harbinense|TrEMBL
MKISTILQQDKIHVSCEIFPPKQSGKLQQTEEVVKELAAVHPDFISVTYGAGGSTKANTV
RLADIVQKHGIPALAHLTCVSSTQEMVRDTLAELRQNHIENVLALRGDLPQDGNVPVQQQ
YRYASELVCEIRSQGDFCIGAACYPEGHVESTSREEDIAHLKEKVECGCDFLTTQMFFDN
NVFYSFLYRILAKDIRVPVVAGVMPVTNARQIARICALSGAALPPRFSNMADRFANDPAS
MRQAGIAYATEQIIDLISNGVRAIHLYTMNQPDVALKIFENISEIIK
>I1D281|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora glauca K62|TrEMBL
MGLHDRGRHRPAVPSGVLASRLDSTRYEVLPLPGVLDQTARLAEGTTVTVTASPSRGLDA
TVELCEKLAAQRLRAVAHLAARQVRDTPHLRDVLDRLAGAEVDEVFVIAGDARTPAGPFE
DGLSLLRAIEESGRRPRRVGVPCYPEGHPLLSDDALWAALTAKQPHADYAVSQLCFDATV
VCRFLRLARERGVTLPVYVGLAGVVDPAKLLRVGARIGVGDSLAFLRKNRAALAGFTRSA
HHDPGRFLTALAERTTDGGCVPAGLHFYTFNRVTATVEWVDAARARRAE
>A0A559S0T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibacter sp. Hel_I_33_5|TrEMBL
MKVTDHIKKANGKTLFSFEIIPPKKGKSIQELYSNIDPLMEFKPPFIDVTTSREEFIYIE
KEGLFDRKITRMRPGTLGICAAIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGINNV
MALRGDAMKGEQYFKATKGGHSFATELVAQIQDLNCGNYLHDGVTVDDKSDFCIGVAGYP
EKHMEAPSLNTDLMRLKEKVDAGADYVVTQMFFDNKKYFEFVEAAKNIGINVPIIPGIKP
LAVKRHLQLLPQVFKIDIPENLIQAIDSCKDNKAVRQVGIEFAIEQSKELLAAGVPVLHY
YSMGKSSNIQQIASAIF
>A0A7X7JBD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MTTASTPPGVAARLVDAAAGPSVSFELYPPRTEAGMTALKATVERLAEARPDFFSVTYGA
SGSTQESSREVVRWLLATTDARVVAHLTCVGAPWEYVRRVAEGFLEDGVRDLLALRGDPP
RGTRDWRPHPEGLRSGSELVARLRALGDELGEPLSIGVAATPSARWAAPPDLPVPDGDDL
QALRAKQEAGADYAITQVFFEPSSYARYVAAARAVGVTIPVLPGVVPLADPARLRRLQEI
SGVPVPPPVLVRLDTSEGEERAAVGLRMGLALVHEVLRAGAPGVHLYTFNQHEAVLRLLD
GLRLPRAAATGRPGRAGRPGAVSAR
>C3H695|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar huazhongensis BGSC 4BD1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVADKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAEALLEEQVDGLLLETFYDEFELLHTVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNGGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLIKYVR
EKQEVKEGIN
>A0A7X8KMU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistaceae bacterium|TrEMBL
MRDYFEQERPTLTFEIFPPKRTGELSSIFATVDELASLAPDLISVTYGAGGTSRDNTVEI
ASQIQNSYAIPALAHLTCAGNSVEDVEPILRTLRENGVKNILALRGDLAEGEALKDFRYA
SDLIKYIRSRYDFRIFAACYPEKHIEAYSMEDDLRCLKEKADCGVDVLISQLFFDNELFY
RFRDRARAMGIAAPIVAGIMPITSSSQISRMVSMCGATVPEKVRKIIRAFGHNNMAMKEA
GIAYATAQIVDLLADGVDGIHLYTMNQPDIAKRISENIRGILYSLRVKRG
>A0A850K0T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacteraceae bacterium|TrEMBL
MLTDKIRNKENGILLYGITPPKVKHTQEEIKEIAKKHVERISKLNVDGLVLYDIQDESDR
TDEKRPFPFIKTINPCEYSRNYLQELKTPRIVYRAVGNYTAKQFATWLESTTATQVHSVF
VGAASHEQQTNITLKEAYSIKKEVNDNLCLGGIAIPERHMAKHDEHLRVFSKQNSSCEYF
ITQCVYDVHAAKTFLTDYAKYAKENNIEPVPIIFTLTPCGSSKTLDFMKWLGINIPNYLE
EDLKESGDILASSVKLSRDIFEDLFIYGKKRGIPVGCNIESVAIRKAEIDASVELLEEIK
QIIKDNK
>A0A850H5U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actirhodobacter atriluteus|TrEMBL
MTVQTSPVNDRAHEEFTAHDAPLFSGLPGDISASFEFFPPKTEKMEAKLWDAVSELKPLG
PSFVSVTYGAGGSTRERTHATVARIIDEAGLPAAAHLTCVGASKAEIREVAEHYWEAGVR
HIVALRGDAGEPGAPFTPHPDGYASAADLVAGLKDIADFDISVAAYPETHPDADCPQADL
DNLKRKLDAGASRAITQFFFSAETFFRFRDEAAACGIAAPIIPGILPVTNVAQARKFAGA
CGAEIPAWMDGLFEGLDARPAARQLVAATVAAELCRRLYAGGVRDYHFYTLNRADLAYAI
CHMLGMRPTGA
>Q9A6F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter vibrioides (strain ATCC 19089 / CB15)|TrEMBL
MTLPPTRRVIGPVARAGERTGRPRVSFEFFPPKTPQMEESLWQAITRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASREEVDEVIREYWETGVRHIVSLRGD
PPPGEGGIGGVYVPRADGYANATELTKAVRAIAPFEVLVGVYPEKHPESPSLEHDIDVLK
QKVDAGATLGISQFFFDLDAFLRFVDKVRAAGITIPIVPGIMPVTNFAGLKKMAAACQTA
IPSWLGNLFDGLENDAETRRLIACSVAAEMCAKLQEQGFEDFHFYTLNRADLVYAICRVL
GVREISPAASEVAA
>A0A4Q4D5W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MPVEDPTITALLAESGPSYSFEFFPPKDDAGEEVLWRTIAELEPLQPTFVSVTYGAGGTS
QERTVRVTERIASESRIKAVGHLTLVGQSRDEIAEVLRQYAAAGIDHVLALRGDPKGGPR
APWETHPGGMEYAIDLVRLAHEIGGFTVGVAAFPEGHPDADDLDHDARVLVGKVEAGAEF
AITQMFFRSSDYFGLVERVRALGCEAPIVPGIMPILNFPQVARMAELSGAAMPQEVLDVI
EPVSEDPAAVRAAGIELATQLCRDLLAGGAPGLHFITLNRSKATREIFEQLRSEGLI
>A0A1W1HFV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfamplus magnetovallimortis|TrEMBL
MRVANLYKTQTKPSLSFEFFPPRDENAEEGFYTVLDELSTLNPDYMSMTFGAGGSTREGS
YQAVKKMIEEKKLPTVAYLAGFGLAPHEITEILDRYKDLGVETIFIIRGDEPRNSDFKPH
PESFKYASDILKFVSGKYDFDLGCAGYPEGHINAPSLEKDIEYLKLKQDNGAQYVIAQYF
YDNEFFYSYIDRCRAAGITIPIIPGIMPIYTVKLTKMLCKLCGSTIPADLQARLDAFPEK
PDPNEVAALGVDVAFEQCLDLLTHGVDGLHFYTMDRSPSVTKIIQKLREKGSLT
>G8Q2K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas ogarae (strain DSM 112162 / CECT 30235 / F113)|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGASSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1W6KP66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. CIAT894|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWQTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGIKIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGLDEFHLYTMNRAPLVSAVLDNLGFSRRAPKSAGAAA
>A0A0C1F9J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kaistella jeonii|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFEPPFIDVTTSREEYIYLD
KGNGLMERKITRMRPGTLGICSAIQHKYNVDTVPHVLCGGFTQEETEYLLVDCMYLGIEN
VMALRGDAMKGQQYFEPTSGGHKNAMDLVHQMNDLGRGKYLHDENILDENNKFCIGVAGY
PEKHIEAPSMNYDLKWLKEKVDAGADYVVTQMFFENKKFMEFVKQAREIGITVPIIPGIK
PIATKSHLQMLPKVFKIDLPEDLISAVEKAKDNTAVKQIGIEWTINQCRQLLDFGVPVLH
FYSMGKSDNIKKIASELF
>A0A7L0Q5G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Setophaga kirtlandii|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLRDKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDHMGAGGPLFIDVTWHPAGDPGSDKETSSMIIAYTAVN
YCGLETILHMTCCNQSKDDITGHLHKAKRLGLKNIMALRGDPAGEEWEEEVGGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAQSYEADLRHLKEKVYAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWSEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVRALLKVLRKYELRVNY
HIVNVKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A4R5LW16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Seongchinamella unica|TrEMBL
MVAKPRISFEYFPPKTEAGREKLLNETTPALNELNPEFFSVTYGAGGTTRDTTLGVVSAI
GATGIDVAPHLSFGGDDEETVAALLETYRERGIKRLVALRGDMPSGMGAAMQLVHANDLV
GFIRERTGDHFEIEVAAYPEIHPESRSYDSDIQFLRKKLDAGANSAITQYFYNVEAYFYY
LDQCAAAGIDKPIYAGIMPITNYQNLARFSRNCGAEIPRWICQRMESYGDDLDSVRKFGL
EVVTQLCQTLIDSGAPGIHFYTMNQVEPTREIYNNLGL
>A0A1S1F5X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. HMSC070A03|TrEMBL
MSGFLQTLSKNVLVADGAIGTILYSEGIDTCPEAYNLTHPKKIEQIHRSYIEAGADVIQT
NTYGANFEKLQAFGLEHQVRDITRAGVRIAKQAANEDTFILGTVGGFKGVKQNDLSLSTI
LYHTDIQIETLIDEGVDALLFETYYDLNELLQVIRATKKKYNIPVIAQLTASSTNYLQDG
TEINEALKQVEAEGADVIGLNCHHGPHHMQQSFTHIEIPQHAILSCYPNASLLDFEDSTI
HYSDNASYFGKIAETLVKEGVHLIGGCCGTTPEHIRFIKQAVEGLKPTLEKKVIPIRRKS
NYPSIPVKKNNLTTKVKAGPTVIVELDTPKHLDTTKFFANVTKLDKAKVDAITLADNSLA
TVRVSNIAAASIIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKV
GHLPGATNVYDVNSRGLTELAVRFNQGLNIDGGALKTKTNFNIAGAFNPNVRKMEAAVKR
LDKKVDCGMSYFITQPVYTVERIQEIAEKTAHLDTPFFIGIMPITSYRNATFLHNEVPGI
SLPDEILDQFEAVKDDKQKTKELSLRICRKLIDEVIKHFNGLYIITPFEQVDFSLELTHY
FKKQTAKNQEAII
>A0A701QXK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 58:a:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>R6JZ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:248|TrEMBL
MDNIRDYLKDNILITDGAFGTYYAGLYDTRELPEKDNINYKDRITAIHREYIEAGARLLR
TNTFASNTINLDTDIEGVRANIKAAVQNARQAALLSGKGVYIAADIGPIPNDNMFDRQIT
ENEYVQIVNTFAKLGVNIYVFETFSDISHIIEAIKAVPKDAFIIVQFAINQYGYSSSGLS
ARKLISLADEIDSVDAVGFNCGIGPAHMEQFVSRNRKYTKKIFTALPNAGYPQVISGRMV
FSDKNIEYYSQKVCDLVRAGADIVGGCCGTTPDYIKNISEMIRSSHISCNINIDADGDFN
KTPVKNSAFYCGKEGKKLIAVELAPPFDSDADKLMDAAHYLKEKGVDVLTFPDSPSGRTR
ADSILIAAKVSRQTGMCVMPHLCCRDKNAIAIRSQLLGAHINGINNFLVITGDPIPQMIR
SSVKSVFNFDSVGLMNIIEDMNEDQFKQEPIVYGGAINQGRKRLDIEISRVKKKMEAGAA
FFMTQPVFSDEDIKRLSTIKKETGARILCGIMPLVSLKNATFMKNEMAGIDVTDEVLSRY
SEDMTKKEGEAAGVKLAVDMINKTKDIVDGYYFSFPFNRVYMLEDILSMSQI
>A0A847PTG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp|TrEMBL
MLFNFREKLNSSKFLVTAEVSPPKGTRYSVPLEDIRQLKGIVDAVNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDFPSCGDHPGSKP
VYDLDSVQLMQLVRKLDSGIDFVGNKLDGGTSFCAGAVSGIDPEKPLQLIKLEKKVRCGA
DFIQTQAVYDVGMFEEFMEAINHLEVPVIAGLIPLRSLGMAKFMNKNISGIHVPEEIMFR
VKDAPDPVKEGLSIASETIKELMKLSRGVHIMPVGSHENTPKLLSMAGISRK
>A0A512LCA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuriferula plumbiphila|TrEMBL
MMTMNMTESMLVSPPDALVNVNAIRHALTSAQFFWTLEFVPSVDKVLRDELNKIEGLLAS
VKNYPLIAGFSVSDRVHSDRDPDPVTAASHLAMRSGKQPLVHWSGKGRDIMDLHKSIARM
GDMELENMLLLTGDKLKEAAPGDRHRYLESVPAVEEVKRFNPNLLVAVALNPFKYREEDC
MAQYLKLGKKVGAGADYVVTQIGFDNAKYQEARDWVEKRNYQVPLVANLMPMLAKRARYM
RKHQLAGVTVTDSFLALLEEEEKLPDQGVGRSMRRFALQIIGMRFLGYAGVQLTGIHTSK
QFAHLQSQVAELNDFCKDENTWRQAWQECMSFPQGGMAETAPPRAWYLSGQRVAHASVSE
RLKYRIMEHTHDFMFSNGPGAWLFGKLMRPIRPRHGKLDHAVERFERMVKSPLFGCETCG
MCRLAATQYVCPETCPKGLANGPCGGTIENLCEFRDRECIHSVKYRIAKDAGVLDQLETW
LVPAVPKEIRHSSSYPPHFRGEGPEIRVVQFKKPLNK
>A0A0D9AJA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MSQPRSHNFSFEFFPTKTDAGHEKLIATARRLAEYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKQELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFETDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDADSIHA
FGEQVISEMCEKLLAGGAPGLHFYTLNQAEPSLAIWDNLKLTR
>A0A1I6IH22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium azadirachtae|TrEMBL
MSFDVPPFAPTGAVSPRVPISFELYPPRTPAPVEALHETIQQLASVSPRFISVTYGAGGS
VGGRSLDVLRYIREQTTVEPLAHLTCVGSTYAGASRLIREFLDAGILSFLALRGDPPLGE
SEPFLGDLESSAQLVQLIDRAQAERAPYQERPIPGVPGAVQVTPRRKVNIAVAAYPNGHP
RSTYRNQDIDALLAKQAAGATLAITQLFFHPDDYFAFVARARRAGVTIPILPGIMPITSP
ARLRRVLELSGEELPAELSIALEVEPTTEGRTEIGVAQAAALVRELVDGGAPGVHLYAFN
QHRTVLDVLEEAGVLDAAPPASRHVDRRSAVPTGRR
>A0A0N1BUW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. AAP58|TrEMBL
MLDVTGPDTTTGPRLAALLQSFSLEMTAKDVPALEEAAGVIPQGTRIAIAFLPGETFEQR
LHAAVRVHSLGFDPAPHLSARRIASESELRTFLEQLAAQAAIRRLFVVAGDPPEPLGPYF
DALSLIRSGMLADLGLESVGVSGYPEGHPDIGEPALWGAMFDKRDALAELGISMTILTQF
GFDPDAIVHWVGKVRDHGVDALIRIGVPGPAGIKTLMRFAARCGVGTSARVMSRYGLSIT
NLIGSAGPDRLVHDLAGQLDLERHGPLSLHFYPFGGIAKTAQWVSDFRVAHAA
>A0A1C6G7I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Eubacterium sp|TrEMBL
MKISEILKNKRTISFEVFPPKNKDGDISSIYSTIEGLKKLSPDFISVTYGAGGSTKGKTV
EIASAIKHEYGIESVAHLSCISSTKEDIKYECERLKEAGIDNILALRGDYPANATNFDPE
NLEFHYASELNEFIGEHFPGQFCLSGACYPETHQEADGFKKDLEALKKKVDAGAEYLVTQ
IFFDNNYYYRLVREARKIGITVPILAGIMPITNAKSLIRTTKMCGCTIPYQLSTMIEAHY
DNPEAMKEIGINYATQQIIDLITNGVDGIHIYTMNRAETAQRVFDSIPAVLKELN
>A0A196QNS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. EhN04|TrEMBL
MTLVSERQAFNRPDDEAAARFRDLVRSASIEATPRQILTTEHLPDLLPAGTCVYVPFLPK
GQFSDTLEASRRLLDLGMQPVPHVPARMAQSRGQLRDWLAQLDESGVDRLLLIAGDSDAV
AGPFPDTLAVLESGLLAQFRFHGIGVAAHPDGHPMADRATLAQALSVKREYARTTATRLW
VVTQFTFDAEVVIDWLQGLGNILEEVPVYIGMAGPTRVKTLIAYAAMCGVGASARMLLRR
PGSARMLGAWKPDDMVRALVQYCLENPETLLRGIHLFPFGGLRQSAQWIREHSGSFETNR
EAVP
>A0A1R3UKG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis sp. JB363|TrEMBL
MGLMLAAPTRLVAPRSPAPRPRHIRDLLDSGDPLFSFEFFPPRNARSQERLWRAIREIEA
LGPSFVSVTYGAGGGTRDLTVETTERIATDTTLMPVAHMTLVDHSVAELRHLIGRLCDAG
VSNMLAVRGDPPGDPDGEWVSHPEGLTYAEELVRLLKESGDFSVGVAAFPFKHPRSADVE
TDTDHFVRKCRAGADYAITQMFFDAEDYLRLRDRVAARGCEIPIIPEVFPVVKLASIRRS
EMLSGAPFPRALAERFERFGDDAEAVRAFGIEHAQNMCERLLAEGAPGIHFITFNQSTAT
REIYREIAPEQRPSAADARP
>A0A1L8ZF75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus obstructivus|TrEMBL
KAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLASPRVSNMAMGALLT
KHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVGDFPGATSVYDLSSI
ELIKMIKEMNDGRSILGKSIGPATR
>A0A6C8YRB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAKADLLNLKRKVDAGANRA
ITQFFLDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0Q6FQ64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sanguibacter sp. Leaf3|TrEMBL
MTASDVPPTPAGGSSATAPPGRPAARPSRQRPTISFELMPPRNPAAAPKFWSTVDHLIAA
RPDFVSVTYGAAGGDRTTAQTVVRRILEHAPVLPIAHLTCVGASRDNVAEVIDEFLAEGV
RSFLALRGDPPRDQPDWEPHPEGINSSDELVALLREVEAQRCADDPSSALRSAARPLTIA
VATFLDGNAAAGTTRSQEVQRLLEKQQAGADFAITQLFYEADSYVGFVDEARRAGVTLPI
LAGLLPMTDPARLARVETLTGVPAPRALVRDLESLADPAARHARGIRASVELAEAVLAAG
APGLHVYTFNKHEAALDLLEGVHLGGGPAHPAPADAGPDLASGPWVGASQPTAALI
>A0A7X1VNL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter aidae|TrEMBL
MNTNLKRLLSEKLADHPSLCHPDMPVPVLSFEVVPPRTNAMEQRLWQCIRHLTPLSPRFV
SVTYGAGGTMQARTQATVLQLKQETTLVPAAHLTCIGATREEIDDIARTYWQAGVRHLVA
LRGDAPAGTDYAPHPGGYAHASDLVTGLRRIADFEISVAAYPETHPTALSPQADLDNLKR
KLDTGATRAITQYFFEASTYLRFLDRCLAAGITAPIVPGIMPVSNYDQIARFSGLCGVRV
PSWLTRLFEGTAKNPELCRLTACIVAAEQVRTLQSHGINEFHFSTLNRPDLTGAIAYLLG
PRPARETDS
>A0A7W5Z2X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudochelatococcus contaminans|TrEMBL
MSSHANHSGFRASRNTSRPASVSFEFFPPKTPAMEETLWASIKRLEPLSPAFVSVTYGAG
GTTRERTHTTVKRIVDETPLRPAAHLTCVSATKGEVDDVIRSYLDAGVRHIVALRGDPAG
GLGTRYEPHPEGYASTPALIEGIRAIGDFEVSVAAYPEKHPESDSFAVDIDVLRQKVDAG
ATRAITQFFFDNDVYFRYLDKVRGAGINIPVVPGILPVQNFRQTAAFAERTGAHVPAWLA
HRFDGLDDDAETRRLIAAAVAAEQVFDLVDRGVTDIHFYTMNRADLVYAICHLLGLRPPA
TIQQATA
>A0A7V1WWB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSMESRLKKVLDQGGFAVTAECGPPKGADAAAVLKKAELLRDKVDAVNVTDNQTAIVRMS
SLAACAILKGAGLEPVLQMVVRDRNRIALQSDILGASAIGIPNVLCLSGDHQRFGNQSGC
VGVFDLDSIQFLQVVKGMRDEGVILGGEPLDTAPDLFIGAAANPFADPLEFRVTRLAKKI
RAGADFIQTQCIYNLDRFETWLSMAADRGLTEKTRILGGVTPLKSAGMARYMKERVSGMD
IPDEIIKRMDGVSKENQREEGLRICVETISRLKELPGVRGVHIMAIEWEAAVGEIAERAG
LLPRPGIDKG
>X7E5A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinomonas ushuaiensis DSM 15871|TrEMBL
MKSELATKFQDPNRGVYFIGTTPPRSSVEEEQLEQISNKLLERLAGVEADGLIVYDIQDE
TSRIDKPRPFPFMETHDPRAWSKRLHTQSGKPVITYKSVSSRSSEEFSGWLTEAWEDFGI
RDLVLVGSPSSNGDIKLPLPKAYDTLKASPHDFNLGGVTIAERHAKKGDEHLRLMKKSDA
GCEFFISQAVYNHQATADLISRYARECKEHGEEPKRIILTFTPCGSAKTLEFMEWLGISV
PDATKHRILDSATPLDESIKICRNALEQIIEIALPLDVPLGLNIESLTNRKEEIDASIQL
YKLLKATLDLKLAEKGLK
>A0A162RL58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus crassostreae|TrEMBL
MKPDLRKALENNVLIGDGAMGTFLYQMGFPVGISYEEFNLTAPEVVADVHRRYIAAGAQI
LESNTFSANFDKLSKYGLESKVEEINRAGVRIAREAAGADAYVVGAVGSIRGGKRTNMST
KELKQYFAEQISILLDEGVDGILLETFYDVEELLIALSRVRKLSDIPVICQFAVEDVART
LDGYTMPEAFRILQQKGADIIGFNCRTGPNGIMRAVESLSGQLSVPVSVFPNAGVADYVD
GEIRYTAKPEYFGQMAVRFADLGARIIGGCCGTTPEHIQEISQALHGYIPKPIDRTPVME
LEAPIVIQDSLEGNIEDDDREPNLVDLVKQRHTVIVELDPPRDLDIKKFMIGAKALKTAG
CDALTLADNSLAVTRMSNMALGYLAQAEIGIKPLIHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKANFQVGAAFN
PNVKYLYKAVERLEKKIAAGADYIMTQPVYDPKLIVAIKEATAHLDTPIFLGIMPLASGR
NAQYLHNEVPGIQLSEEVLTRMSGLEGEEGRAMGVTIAKELVEVAMEHFNGIYIMTPFMF
YDMSVQLMEYVWEKSGRELSPLFRS
>A0A3A4YZN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSDYKAGSNLEKVLKAGHFAFTGECGPPQGANIEKLKEKASHLKGCVDAVNITDNQTAVV
RMSSWAASLTVQQEGLEPNFQMVCRDRNRLAIQSDVLGVYSHGIRNMLCLSGDHQRFGNH
PEAKNVFDIDSIQLIKTVKVMRDEGKFMNGQDIDVPPRLFIGAASNPFAEPYDFRAYRLA
KKVAAGADFIQTQCIYNMERFREFMKRVVDMGLHEKCFILAGVTPMKSVGMAQYMAKQVP
GMDVPESLIKRLRGAPKGKVADEGIKFAVEQIQEFKEMKGIAGVHLMAIEWEHKVREIAE
LAGMLPRPTV
>A0A2P8VF83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Siccibacter turicensis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDASPDELRCIARDYWNNGIRHIVALRGD
LPPGSGKPELYATDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMYA
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVIAA
>A0A2P7TQG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium UPWRP_1|TrEMBL
MKVTEHLINRTKTLVSFEILPPLKGKSIHALYRILEELLEFKPPFINVTYHRAEYKYKLL
ENGLFEKTYIRKRPGTVGICAAMMYKYGIDAVPHLVCGGFARSETEDALVDLNYLGINNV
LLLRGDAVKPETHFVPEPKGNKNALELVQQVVNLNNGVYLEEELSNGYKTDFCIGVAGYP
EKHAEAPNMKTDLQYLKQKVDAGAHYIVTQMFFDNSKFINFVNACRSMGIEVPVIAGLKP
ITRKSQIYSLPSTFNISIPEELTDAVAACTTDEAVEQVGIEWAVQQCRQLIEFGVPCLHF
YTMSNTRPIQQIMKKLF
>A0A2A3CYC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3864|TrEMBL
MSIRHQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVF
LGAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>A0A2Z2H4G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kushneria konosiri|TrEMBL
MSDSSAPELSFEFFPPRTEAGRDRLPEVYTKLAELDPRFFSVTFGAGGTTRDFTFDAVKN
ISRDTGICTAPHLSCVASDKADLRRLLTQYREHGIKRIVTLRGDMPSGMLGLGEFRYARD
LVDFIREETGDHFDLTVAAYPECHPQARNFEQDIDHFADKVRAGADMAITQYFFNPDAYH
HFVDRVRARGVDVPILPGIMPITNYTKLARFSEMCGAEIPRWVRRQLESYGDDSDSIQAF
GHEVVTRLCQQLLDQGAPGLHFYTLNQAEACTRIVSDLSLEKAGR
>A0A3D6C4B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSFQEKLSSGEFVVLAEMDAPKGIDISDLITHAGHLKSRIDAVVVPDMDNGVMQMSALGC
GALMKQQGIEPMIHIYGRDRNRMALQGDLLAAHVLGIHNLVVVQGEEMINGDHPDAKVVD
DVDEEGLIKMVSKLTSGTDLAGFDLKGKPALSAGCTIAPVTNDAELDAEKEKAAKKVAAG
AKFVILPPVFDIPFYTKMIESISSLNVPVIASVFLLKNVGMARYISINDPNSRLSEDIIR
RIRKASDREAECVAIAGEMIKSLKQVSQGIKISALGWEDRLPAILDSAGL
>A0A353HAJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MNNVSQIQRVLERGEFAVTAECGPPKGADPGVVLKKAETLRENVDSVNVTDNQTAIVRMS
SLAACTLLKTEGYDPVLQMVVRDRNRIALQSDILGASALGIRNVLCLSGDHQSFGNQPQS
IGVFDLDSIQFVQVVKAMRDKENILGGDALSSPPELFIGAAANPFADPLSFRVVRLAKKI
KAGADFIQTQCIYNLDRFEKWMNMVRDRGLTEKVFILGGVTPLKSSGMAKYMKTRVSGID
IPDEIINRMEGVTKDKQQEEGIKICVETIERLKEIPGVKGIHVMAIEWEEVVGEIVERAG
LLPRPNFDVG
>A0A3A5AHQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSLQDRIRAGKFVLLGEFEPPKGADFSGLLRNALLTKGRLDAVVVPEMANAVLKASSLGG
CAFFQREGIETVLQVCCRDRNRLALQADILAASALGIGNVMAVPGDDIRFGDHPQARTVN
DLDLIGLLEMINRLREGRDLSGIELRGTPSFCVGSTMDAGAPGGLLTIEMENLKRKVDLG
IEFAITNPIFDLRRFEQFVKRLEVKIAVLPTVLLLKSAGMARYIDRNVKGISIPPETITR
IQKASDKVKECVLIAAETVARIKEMGMAGVLISTVGWEDKLPWILDEAKV
>A0A2P7MTC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium usitatum str. Tous|TrEMBL
MVPSGAIGLLLQRALASGQPALTAEVMPPRGGDPSRSLAAAGSLRGWVHAVNVTDGSRAV
MRMSSLALCRLLLDAGIEPVLQLACRDRNRIALQAELLGAHALGVRNLLCLTGDPVRAGD
QPGARPVNELEAVRLLQLVQQFNGGQDPVQGELPDGPTDLFAGAAADPQSASWSGLKSRL
LRKKQAGARFIQTQMVMDAEALKRFVGDLAAPLDLPVLAGVFLLKSARNAAFINRVVPGA
NIPQAVIDRLAAAPDPAAEGIAIAAEQVGAYLQIAQGVHLMAIKAEERIPAILLQAGLKP
LALG
>A0A2S4HL27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marortus luteolus|TrEMBL
MANRYSFEFFPPKTEAGREKLKDTRSQLAALNPEFFSVTYGAGGSTRDNTRGIVLETKKA
GLSVAPHLSFGGDDESDILELLNSYKDAGIDRIVALRGDIPSGMGATRLVYARELVEFIR
KHTGDHFQLEVAAYPEVHPDAKSYDADISFLKDKLDAGANSAITQYFFSADSYFYFLEAC
DKAGIDKPIYPGIMPITNYNNLARFSRNCGAEIPRWLSKKLEGYSDDQQSIIDFGTEFVT
ELCHILMEGGAPGIHFYSMNQVEPIKSIAEAVMQSHP
>A0A2K2VXK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKAGSHLEKMFAAGHFAVTGEMGPPRGADAGHIHEKAKYLKGMVESVNVTDNQTAVVRMA
SMAVCRLLLDMGIEPNLQMVCRDRNRLAIQADLLGAAALGIKNVLCLSGDHQKFGDHPQA
KNVFDIDSMQLIATCKKLRDEGKLINDHECEGVPQYFIGAAVNPFADPFDFRVTRLAKKI
EAGVDFLQTQCIYNMEKFRTYMQQAYDQGLTEKCYIMAGITPLKSVGMARYMQKFVPGLE
VTEDFIERLKGVDKKKQGDEGIKMAIEQIQEVKEIKGVAGVHVMAIEWEERVEEIVTGAG
LLPRPEIS
>A0A4R6LL37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium saccharolyticum|TrEMBL
MKIKNIFEEKEVVFSLEVFPPSPDVPIENIYQTLEELKDIDPDYISVTYGAGGGVRKNRT
CELSSIIKEKYDVEALAHLTCINSDRETLNKILSRLESKNIENILALRGDKPVDGEAIGD
YNYAYQLIEHINKNNDFGVAAACYPEGHLETDSLEQDLEYLKQKVDCGVDYLISQMFFDN
SLFYEFRSKAEKKGINVPIEAGIMPVINKKQVGRIIELSDAYFPEKFQKILDKYDDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKAD
>A0A5K1MI99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii NIPH 615|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKARINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A0F5ZSN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grimontia sp. AD028|TrEMBL
MGYSHASHLDALNQNLSDLNGDINVSFEFFPPSSEAMEQTLWASVQRLKTLKPKFVSVTY
GANSGERDRTHGIVKSIKQETGIEAAPHLTCIDASRDELREIARDYWNSGIRHIVALRGD
LPEKSQKPDMYAADLVELLKGEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIIPGILPVSNFKQASKFANMTNVRIPAWMYKQYE
GLEDDAVTRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPIA
>A0A4Z0KFC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MSQEVLASLLKSARYEILPTAGVVDRVHEYVVPGRVITVTASTGLTLEATLSTAEQLQAL
GFTAVPHIAARMVQGRTELEEIVDRLTQAGIDRIFVPAGDATPPAGGYAGALDLIIDLAS
MAAPIQHLGVSAYPETHPLIPDDVTVQAMWDKRDYATHLVSNLCFDPGTIATWLARVRAR
GIDLPLILGIAGKVELAKLARVATKIGVGESTRFLRKNTVTFTKMAKPGGYNPRKFLDKL
SPVLDNPTMGVAGLHIYTFNQIKDTEIWRRRQLAALGHNDEVPSTS
>A0A4Y8N9G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia dipogonis|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLVTLKPKFMSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHVSCIGSSKESLRAILNQYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLDNFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTDLCGRLIDAKVPGLHFYTLNGAAATKAICERLAV
>A0A3A4XNN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSFQKRLASGEFVVLAEMNTPKGVDISQLITNARRIKGRVDAVVVPDMDNGVMRMSALAG
GVLMQQQGIEAVIHLYGRDRNRMALQGDVLAAHVLGIQNLVVVHSEPMANGDHRDAKTVD
DLDEVGLIEAIQSLQQGKDLAGFDLEGAPEFITGCTLSAYADGAQMAAELEHAEKKIRAG
ARFVVTPPVFDVDRFGDFLGPAKALGVPVIATIFLIKSVGIARYMALNEPGAHISEALIQ
RIRKASDRETECLKIAGETIAALKGKVAGVKIETHGWEHRLASILDYAGM
>A0A7J4RT68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilaceae archaeon|TrEMBL
MTITYEINPPKVIQDTILSHDELQESVNRLKKRAFSIRNVCHSIHVTDSVLGIPRISPIT
IGALIRSSNDVIAISASIRVRDRNLTSLTQSICDAILLKLNSILILKGDPPPAGPKDSKL
VPSEVVKQFNEQGFGKKIDLFLSLPSNPDFAKIHKKIEAQPRGFVTQVVSSLDQITRIVD
KLKPQGFRIIPCILLPSEKNVRSAKILNLDWTNYSNDVVGFIKKAQKIAGDVLISSPNDF
KGAFETLKKLS
>A0A443SZR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylella fastidiosa subsp. multiplex|TrEMBL
MIPISFEFYPPKNDDQRAQLDRTANRLRAFAPEYVSCTFGAGGSTLSYTSETVRHLSQHH
GFDAAPHLSCVGGSRQEIRELLKLYRAIGCQRIVALRGDLPSGMGHPGDLRYAADLITFI
RTEHGDHFHLEIGAYPETHPQASNTLNDLHYFKAKADAGADAAITQYFYNPDAYFHFVDA
VQRLGVTIPIVAGVMPISNFDQLRHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVV
TALCERLIAGGAPGLHFYTLNLAKPSTQVLQRLGY
>A0A7W1U4B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MHITDIMRGGTPTFSFEFFPAKTPEAAETLYQTIRELETYMPHFVSVTYGAGGSTRDLTH
ELVERIKATTKLDPIPHLTCVCHTEEEIDGILQRYAQSEIGNILALGGDPPRGLAYDKKS
DFFQHAVDLVKFIRRFNDSGAHPDPRGFGIGVAGFPEGHPATPNRLAEMDHLKAKVDAGA
DYIVTQVFFDNRDYLDFRERCALAGINVPIIAGIMPITSMSGFKKLAELAAGARFPAKLI
RALQRCENDREMVNRVGVHFALEQCHDLLDNDVAGIHFYTLNRSDATRVIFDSLGIPRRR
DAQLSMG
>W2UNV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zhouia amylolytica AD3|TrEMBL
MKVTEHIERANGKTLFSFEIIPPQKGSNINELYKNIDPLMEFNPPFIDVTTSREEFVYID
KGDGLLDRKITRRRPGTLGICAAIKHKYEVDTIPHLLCGGFTKEETEYMLIDCQYLGINN
VMALRGDAMKHQRYFEPTAGGHPYAVDLVHQIHNLRCGQYLHETLEEGDRANFCVGVAGY
PEKHLEAPSMDFDLKKLKEKVDAGADYVVTQMFFDNQKFFEFLERAKDYGINVPIIPGLK
PIAVKRHLQLLPQVFKIDLPDALIEAVDSCKSNKEVRQVGIEWAIQQSRELKEAGVPVLH
YYSMGKSDNIKAIAEAVF
>A0A4R4TUU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. 7K507|TrEMBL
MRRLRPNRPPTVRDLLASGGRSFSFEFFPPKTDKGARNLWRTIRELESLQPTFVSVTYGA
GGGTRDKTVDIVEHIATDTTLTPVAHFTAVDHSEAELRNLIGRFAAAGVRNIIALRGDPP
GDPMAEWVKHPEGVEYASDLVRMIRSYGDFCVGVAAFPYKHPRSPDVETDTRFFIEKCRA
GADYAITQMFFRAEDYFRLRDRVEAAGCDTPILPGIMPVTQMSTIERSEQLSGAPFPPEV
RARFEAVAHDPEAVRRLGIEHAAELCQDLLDQDAPGIHFITFNKSTATREVYGLLDAGAY
AASGSAPPITA
>A0A2U2AIG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignatzschineria indica|TrEMBL
MSAQYVELLNQSLSELQNDVNVSFEFFPPNSEQMVTTLWNSIERLKVLKPQFVSVTYGAN
ASTRDRTHRVIEDIVYKTDLTAVPHLTCVDTSEEELHQIADNYWNLGIRHILALRGDLPK
GTENPGIYADHLVKLLKKRHDFDISVAAYPEIHPEAKNAQADLLHLKRKIDAGANLAITQ
FFFDIDAFLRFRDRCVAVGIEAEIVPGILPVSNYDSLVKFAGPLNVKIPSWLHKRYEGLE
NDPTTRNLVGASIAIDMVRVLRKEGIQDFHFYTLNRSELTYAICHTLGLRPEPALTIKEA
>A0A2A6NLJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. C9|TrEMBL
MTETISSLPNGQRAPKVPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTISRILRETDLLPAAHLTCVSASRGEIDEIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAAIKKRHADIEISVSAYPEKHPEAADFDADIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFDGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPTGA
QKAA
>B3S098|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoplax adhaerens|TrEMBL
MDCQYGAKKSVITDGIVDDNYDDAHIIQKIRKRINSGDKFYSLEFFPPRTDSGGVNLIAR
FDRLAIGNPLFIDVTWHPKGNSGGDEVTASLTIASAALNFCGLDSMLHMTCINSTTEDID
KYLRKAKKQGLRNILALRGDVSDSIDESVRHTKELKYASDLVKHIRKEFGNYFGIAVAGY
PDGHPECSSYEDDIRRLKEKLDNGGDFVVTQLFFDAETYFKFLRDCRNAGITAPIIPGIL
PIQGYNSLRHLVQLSKLPVPQRILDTIESIKDNDEAIRKFGIVEATNLCKKLLASDDVPG
IHVYTLNREEAVVKLLKRVGLWHEESIYKSLPWRPSANGKRISEDVRPIFWASRPKSYVH
RTMMWDEYPNGRWGSSASPAFGELKDYHIFYLKNTSKKDELLKMWGEKLESVEDVYEIFT
CFVSGERNKYGYKVDALPWSNDALALETLFIKKSLEYINSKGILTINSQPNVNALPSTHE
VFGWGGPNGYVYQKAYLEFFISAERFKTLLEVLPNFPMINYHALDLSESINVSNSDHHQP
IAVTWGVFPGREILQPTVVDPTSFSYWKDEAFALWTNQWANLYPEESKSRQVITAAVRNF
VLVNMVDNDFIQGGNLWKVLDQLFSLEADKAVY
>A0A327Q2Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga skermanii|TrEMBL
MMWRYVIFAGLLKKISSPTVIKRMKVTEHISQAKDTLISFEILPPLKGKSIESIYDHLDP
MMEFKPAFVNVTYHRSEHMFKKRMDGSFEKVEIRKRPGTVGICAAIMNHYNVDAVPHLIC
GGFTKEETENALIDLAFLGVDNVLVLRGDAPKNETYFEPEPNGHRYAIDLLHQVQHMNNG
IYLEEDLQNGVKTKFCIGVAGYPEKHFESPNLNSDLQILKAKVDAGAEYVVTQMFFDNQK
YFEYVKLCREMGINVPIIPGLKPLTTKKQLSVIPRSFQVDIPTEFSNEIMKCKTDKEVEQ
LGTEWLIQQSKELKAFGVPVLHYYTLGKPLVIRKVMEAIV
>A0A3E1KQL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas nasturtii|TrEMBL
MPALTAAAPGILRGTTMFIPYLPGQDDSAHLAAAQRVRTLGFSPMPHLSARRIASLDALQ
GFVRRAADDAGVAHCLVIAGDASSPRGPFPDSLSLISTGVFERAGIQTIAVAGHPEEHPN
MHASERWDALERKCRSIAARGMAPLIVTQFAFDADIVLTWLQALRTRGLAYPVRVGVPGP
AGVAVLARYAARCGVGASASMLSKYGISLGKLFGTARPDRFVDRLATGLTPAHGDVRLHV
FPFGGIAQSVAWVEQYRARTASAHLIGPGSATITPDFER
>A0A7Y2F712|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pirellulaceae bacterium|TrEMBL
MSLADHYTGSNCAISFELFPPKTEAGIKTLCQNVKRLMEFRPSYFTCTYGAGGSTRGTTL
DVLAKVREITKLPVASHLTCVGSTVEQLVDYLQEAKSQGTGYIVALRGDPPKGSETFEAV
EGGLRYANELVDLIRREFADDFGIAVAGYPEVHQEAPDATTDLDNLKRKVDAGADVIITQ
LFYDNADFYRFRDACVAAGINVPIVPGILPVTNFKQATRIATMCKARIPKELESAMNESD
DADYQFDIGVDHARQQTVDLLNNDIPGIHYYVLNKSDAAEKLIEGLPLGVDAK
>A0A7X3NS65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MTTILRKKDNFMESLAHRILVCDGAIGTELRKRIPAYLQCVDACNISTEHAEKVTAIHRA
YADAGADVIQTNTYQANREALAVHGLAEQVDEINKMGVVLAREAVPETCYVAGSVGQVSF
QSLDSPAPSTKTIRRIFKEQMDALVDAGADLLVLETFVSPKQAEIATKQALTYSVPVVVE
ISGISGGTVGAGLDVRVFAQELEQLGAHSVGINCRGPHDLVEAMELLAPVIKAPIVVQPN
AGNPRVEQGEVAVSYTVEAEVFSDYVGKLVELGANMIGGCCGTTPTYTAKIRQAIAGREP
VQREARIFVLPKITSTSKAPTDNPVQQVFETRERIVSVEMRANTFPQLRAMLKEAKGLAA
IGVDLFDVTDNSGAAVNIGAVGTAYRLQQATQIPTLIHWTTRSRNLISMQSHLLEAEALG
IRGIVALSGDHPKAGPYETASLVPDVRGAVQLMKLIARLNQGELADGSSIGEPCGFYYGG
GFTIAENLQPHVKHLTNKVAQGANFAYTQPVWTYEDIVRTQQATEYLGIKILYGILPLTS
FRSASYLRDNLGLYIPQFIVDKFRDLGDTAGHELGMRLCLELVRDIHNQGECEIDGIYLI
PPARMNWKNRARVISEIVKTYR
>A0A8J8GIN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calidifontibacillus erzurumensis|TrEMBL
MGILKELQNRILIADGAMGTLLYSFGVDYCFEELNLLQPDRITKIHEAYIEAGAEVIQTN
TYGANYLKLARYGLEDQVKDINAAAIKIAKKAANGKAYVLGTLGGIRSIKKSAATIEEIK
RSFREQLYTFLLEGVDGLLLETFYDLDELKTVLQIARKETELPIIAQVSIHEVAVLQDGT
PLADALKQLEDLGADVVGLNCRLGPHHITKALEEVPLPERAFLSAYPNASLPDYIDGRLI
YESDAEYFGECAVNLRNQGVRLIGGCCGTTPRHIKAVREKIQGLAPITYKEVKVKQTEPT
VTVLSKRNKPHLHEIVAKERSVIVELDTPKTLNTTSFLEGAKALKEAGIDALTMADNSLA
SPRICNMAMAAIVKNELGIRPLVHITCRDRNLIGLQSHLMGLDALGIDQVLAVTGDPTKI
GDFPGATSVYDLSSFELISLIKQLNEGITFSGKPLQKKTSFSVAAAFNPNVRHLDKAIKR
LEKKIKHGADYFISQPIFDEKKFLEVYEHTKHLSKPIYIGIMPIVSSQNAEFLHNEVPGI
KLTDEIREKMARCGSDREKAKMEGIAIAKSLIDAAFDLFNGIYLITPFMRYDMTVKLVQY
IHQKCANRVQERKITN
>A0A6N9CA84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MNTASTDTDLNFDDSQKPSFRQLLQETDTFLTCVEVVTSRGTITDSDGGRVLELAQKLAD
NSRIHGLSITDNPGGNAMIGPDTLGRDLLSRSQEVIIHLSCKDWNRNALQSRAWQLASEG
FDNILALSGDYPIDGYRGQASPVFDTDSVGLLKMFADMNAGMTVGIGKRAQVLEHTNFFL
GAVVNNHKRYEREVMPQYFKLKKKIENGAAFIINQIGYDSRKQDELLRYMAIHNLEVPVI
GNVYVLSRPAARFFNKGNIPGVTVTDELLSLVEKEGKSKDKGKAFLLEFAAKQCAIAKGL
GYRGVYLGGHLRYKDYEKILKTVDGFGEDDWKDFVKEICFHYPDEFYFFEPEQETGLSST
EINREYLFSKRAEGLKAAKGEIPVGYKINRAVHDQVFEQGSLGFTIGKRISKAIDGASER
VKKAMHGLEQAVKVTAFDCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTRQGKCEIGE
KDCIWARAYDRLKAYGEEETMLDGPAIFKDGALNGTSAWGNTFLERDHHAKNNE
>A0A495Z6D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MTTTPTKKENFLESLKHRVLVCDGAIGTELRKYIPENLPCVDACNISDEHVEKVVEVHRA
YAHAGADVLQTNTYQANREALAVHGLADQVEAINRAGVRLARSGAGESCYIAGSVGQIPF
YTEDATETHTEPSTKKMRQLFKQQMDALVDEGVDLLLLETFVSSKQAEVATKQALTYDVP
VIVEISGISGGTVGTGLDVRVFAQELEQLGAHAVGINCRGPHDLVQAMELLAPVITTPLV
VQPNAGNPRVEQGEIAVSYTVGADVFTDYVHKLINLGANMIGGCCGTTPEYTAKIRQAVT
GKKPVKRYPRIFVLPKRSATHKSQRDNPVQQVFETRERIVSVEARANTFPQLRALLKEAK
VLAALGIDLFDVTDNSGAAVNIGAVGTAFRLQQATHIPTLIHWTTRSRNLISMQSHLLEA
EALGIRGIVALSGDHPKAGPYESASLVPDVRGAVQLMKLISRLNQGELADGSSIGDPCGF
YYGGGFTIAENLAPHVKHLTNKVAEGAKFAYTQPVWTFEDIERAQKATEHLGIKILYGIL
PLTSFRSASYLRDNLGLYIPQFIVDKFRDLGDTAGNELGMQLTLNLVREIRNQDTIPIDG
IYLIPPARLNWKNRRGVISEIVETYR
>A0A7X3ZKU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MTYSRLSDNFMESLSQRVLVCDGAIGTELRKRIPVYLSCVDACNISDEYAEEVVKIHHAY
SVAGADVIQTNTYQANREALAIHGFGDRVEEINRAGVRLARSGTGKSCYIAGSVGQITFQ
TEDASEPVVEPSTKQIRQLFEEQMDALVDEGVDLLILETFVSTKQATIATKQALTYNIPV
VVEISGISGGTVGTGLDVRVFAQELEQLGAHVIGVNCRGPHDLVQAMELISPVIKAPLVV
QPNAGNPRVEQGEIAVSYTVGADVFTDYVHKLIRLGANMIGGCCGTTPEYIARIRGVVAD
QKPAKRQTRIFVLPKSSPSNKAQRDNPVQQVFETRQRIVSVEARANTFPQLRALLKEAKV
MAELGVDLFDVTDNSGAAVNIGAVGTAFRLQQTTHIPTLIHWTTRSRNLISIQSHLLEAE
ALGIRGIVALSGDHPKAGPFESASLVPDVRGAVQLMKLISRLNQGELADGSSIGDPCGFY
FGGGYTIAENLDPHIKHLTNKVAEGAKFAYTQPVWTFEDIIRAQQAAEHLNIKILYGILP
LTSYRSASYLRDNLGLYIPQLIVDKFRDLGDTAGRELGMQLTLDLVKEIRNQNSIQIDGI
YLIPPARLNWKNRRLVISEIVKTYR
>A0A7X3VRT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
QALTYSVPVVVEISGISGGTVGAGLDVRVFAQELEQLGAHSVGINCRGPHDLVEAMELLA
PVIKAPIVVQPNAGNPRVEQGEVAVSYTVEAEVFSDYVGKLVELGANMIGGCCGTTPTYT
AKIRQAIAGREPVQREARIFVLPKITSTSKAPTDNPVQQVFETRERIVSVEMRANTFPQL
RAMLKEAKGLAAIGVDLFDVTDNSGAAVNIGAVGTAYRLQQATQIPTLIHWTTRSRNLIS
MQSHLLEAEALGIRGIVALSGDHPKAGPYETASLVPDVRGAVQLMKLIARLNQGELADGS
SIGEPCGFYYGGGFTIAENLQPHVKHLTNKVAQGANFAYTQPVWTYEDIVRTQQATEYLG
IKILYGILPLTSFRSASYLRDNLGLYIPQFIVDKFRDLGDTAGHELGMRLCLELVRDIHN
QGECEIDGIYLIPPARMNWKNRARVISEIVKTYR
>A0A7V0W079|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MKIDDILKDKKRSISFEFFPPKTEQAEQALFETIEKLSSFNPSYVSVTYGAGGSTRDKTM
STVQKIKQKTSLTVMPHLTCIGSEKKEISEILDFYKSIGIENILALRGDPPMGVTELPDI
KDGFDYAKDLIEFIETYEVFSIGAAAYPEKHKESPNMEFDMIYTKDKVEAGAKFLITQMF
FDNRFFYGFLDRAEMIGIDVPIIPGIMPITDLKKIKQLSLMCGASIPNPLNSLINKYGDN
PEDSRKAGMEFTIEQCRNLMENNVRYFHFYTLNRWEAVSEIINILKLFPI
>X8K6H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sulci ATCC 35585|TrEMBL
MKISDIIKEKGFAASLEVFPPKNDLNIDTAIPLLDELSTLKPDFISVTCGAGGTIQSDNT
AKLCAHIKENYDTEPVAHFTCITSTKQQVADRLALLKEKGIENVLALRGDRPIEGLSISP
EYTYAKELIKEIKAEDFCVAAACYPESHIDCGDLDAEIEHTKQKVEAGASFLISQLSFSS
DIFLNYLSKLRNAGVDAPFLAGIMPILSKAQVERMIYMCGVSLPGNIVRILAKYQDNKED
LEKAGIEYACSQIETLKKEGVDGIHIYTMNKPHIAKALMQAARQ
>A0A2E3BCS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleispira sp|TrEMBL
MLIEKIKNRESNIVLYGITPPKKGTSDDXVAEISARXVERLQDQNVDGLVLYDIQDEKSR
TDEERPFPFMETLDCYDYSQQYLTNLKIPKIIYRAVGKYSETELSXFLTQADPQXNLSIF
VGAASKSQEVTLSISDAYKIKADTXXDVXXGGVVIPXRHQSKGDEHLRVFEKIAQGCXFF
VSQGVYDVXASKNFLSDYYYYGKENNXPLVPILFTLTPCGSAKTLQFMKWLGISIPKWLE
NDLIHSNDILQRSVDVSEQSYRELKAFADEKGIPVGCNIESVAIRKVEVDASIELLERVS
KA
>J9DXZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|alpha proteobacterium IMCC14465|TrEMBL
MTSISFEFFPPKSAEAEKKLWEVVNELATIGPDFVSITYGAGGSTRERTHNCVKHLVSET
DLSPAAHLTCVAASKSEVDEVIEDYAKAGVKHIVALRGDMPDMEAFSPHPDGYQGSVELV
ETLARRGGFDITVSAYPEIHPESGNMQTDIDLLKAKIDAGASRAITQFVFDTEQYYRFRD
VLDDNQINIPVIPGIMPTTNFKGVLRMSEACGASVPEWMKNKFAGLDDDLESRRALAIEV
ATEQCRDLLNNGFENLHFYTLNQVAVTKAVCGALNLGTASNANPPHINKSEFQS
>A0A1C3NG25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas bromi|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRQLKQKH
GFEAAPHLSCVGGSRQEIRELLEQYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGRKMQAYGDDADAVRAFGAEVV
AALCERLIAGGAPALHLYTLNLAKPTTQVLQLLGR
>A0A0S7YWF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium SG8_13|TrEMBL
MSTEGNGYKSGSNLEKVLAAGEFAFTGELGPPRGCNAEEVRHKASFLKGNVDSVNITDNQ
TAVVRMASWAACLLLIQEGLEPNFQMVCRDRNRLAMQADILGAYAHGVRNMLCLSGDHQM
FGDHPQAKGVFDIDSMQLIRMVKTMRDEGKFLAGDELDGVPKMFIGAAANPFADPFEWRV
HRLAKKVDAGVDFIQTQCIYNMEKFREWIRQANDMGLTEKAYILAGVTPMKSVGMAKYMK
NRVPGMDVPDAIIERLQGAGKGKVADEGIKIAVEQIEEFKEMKGVHGVHLMAIEWEHKVP
EIAELAKVLPRPQIK
>A0A1D3TPF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobium acetethylicum|TrEMBL
MGRQKSSMKIETIFEKKKPVLSFEIFPPKKEAAIKNIDETLEALSILHPDYISVTFGAGG
SCTNNLTVEIAKKIKHRYHIEPLVHLTCINHSREEICMILDQLKEADIQNILALRGDINP
EIERKHDFEYASDLVKFIKENGDFSVGGACYPEIHMEARDEIEDILNLKKKVDNGAGYLI
SQLFFDNEVFYDFQNKAKIAGIQVPIEAGIMPVINKAQIEKMVSLCGASLPGKFSRMMQK
YGNDKEALFDAGIAYAINQIVDLLAHDVDGIHIFTMNNPEVAKRICEGIKTLI
>A0A1Q9K0I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerostipes sp. 992a|TrEMBL
MTFREYLKEHILIMDGAMGTYYDSLKSDKNQIAEEANLADPVFIKSIHKEYLNSGAKLLR
TNTFAVNRFMAISKGLETKEEQDHYMNQSIKAAYEIAKAAIAECGKEAWIAADIGPISET
LFYEDEYQEREEYQILIDAFLECGADIFNFETFADSAVVEWAADYIKSQKPEAFVMVSFA
FNRNGYTTKGHSAKRLFQEVAAIEHIDSYGSNCLIGAGQMHDILKGLSFSDKKYIQALPN
SGYPQIMRGRTIYSEGASYYSEKMQDIANLGFNILGGCCGTTPKHIQALAQIIGCQKPSE
KRTCEEETSGVPVSKTRNNSFVKKLQQGKKVIAVELDPPFDQNAEKLLEGAYQLKKQGVD
IITLADSPLARARADSVLLGSKIHSMVDIPVMPHIACRDRNRISMHSTILGAHINGIKNF
LIVTGDPVPSGERDTTKGVFDFNSIRFMEYMKEINGELLFQDPISYGGALNQNQANLDKL
ILRMQKKIDAGVSYFLTQPIYSQQDIDRMRIIKSRLDTKIICGIMPLVSYRNAMFIKNEM
PGIFVPDEVVKQYDPDMTREQSEEVAVRISLSVIEKLKDIADGYYFMTPFNRVALICRII
DHMEEKND
>A0A5I5SY31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Isangi|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSQMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A161T6R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIKEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0U3G2Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignicoccus islandicus DSM 13165|TrEMBL
MNTGVVGKEVRELCPKRMLNGPCGGIRGELCEVDDFQCPFYKAFENLRSANYLKPLLDKG
FKVECEPGDVELSGYAKMLEEGGPVLSTEVEPWSLKDVQFFETLKDKYHAFNVTDNPFGK
PHVSSVAVSIELKRRGMEVIAQLTTRSRTREALASDLMSLNAFGVTNVLALTGDWAPHSV
FDLDAVRLVCLISLMNKGLLWDGSEIEPTTLVPGVASNPYFKYEKERLLRKARAGAVFAQ
TQPIFTSEIVRSLKEYPVTTVPSLLISTSRKVVRSLKEKGVKVPKEYEEGLIKSKAEGKA
DEFVLEYNLKLAEEILSKELKGIHVMAPGRWDLLVKFGNALRELL
>A0A2B9E0B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINRAAVNIAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQDGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANIAPVIVKETVPRPKVVH
TQEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPNVRHLKAAVKRM
ERKIDGGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDSAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2B9TND8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRVAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKRLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A4V3USQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter lindaniclasticus|TrEMBL
MASISFEFFPPKTDDQRAQLDRAAQALKAHRPEYASVTFGAGGSTLSYTGDTVARLHTQH
GLNVAPHLSCMGGTRAEIAALLDNYRAAGYRRIVALRGDMPSGMATAGDFRYAAELVAFI
RQHCGDHFHIEVAAYPETHPQADNALRDLKHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VRKLGVNVPIVPGIMPISNYSQLNRFSEMCGAEIPRWIAKRMQAHGDDADAVRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRAKATQAVLQQLG
>A0A6H9HHW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. TCA1|TrEMBL
MTSAERPVSAPLFEDLPGDISVSFEFFPPKTEKMEEQLWDAITQLAPLAPSFVSVTYGAG
GSTRERTHSTVSRLVRETDLVPAAHLTCVGASKDEIAEIADQYWEAGVRHIVALRGDPPP
AHGGIFTPHPEGYTGAADLVSGLKARHDFDISVAAYPEIHPEALSADADLDNLKRKLDAG
ANRAITQFFFSTDAYFRFLDKALAAGITAPILPGIMPVTSFAAIRRMSGNTEIPGWLERM
FEGLDDRPGPRALVAAVAAADLCRRLYQGGVRDFHFYTLNRAEQAYAICQLLGLRPKAEA
>A0A7L7ME05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SCUT-3|TrEMBL
MALGTSSVRTDRAVTIRELLASGERSYSFEFFPAKTEQGERTLWEAIRRIEAVGPTFVSV
TYGAGGSSRDRTVRATERIATETTLTPVAHLTAVDHSVAELRNIVGQYADAGIRNMLALR
GDPPGNPQGEWVQHPQGLRYAAELVRLIKESGDFCVGVAAFPEKHPRSADWDSDIKHFVA
KCREGADYAVTQMFFHVEDYLRLRDRVQAAGCDTPIIPEIMPVTNVRQIERFAQLSNADF
PAALADRLNAVRDDPAAVRAIGVEYATRMSAELLEQGAPGLHFITLNHSPATLEIYQNLG
LHQRTT
>A0A371IUJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Romboutsia maritimum|TrEMBL
MSLLKETLESGKFAVTTEMAPPKGTDLSHLLECAKPLVGRVHAANVTDFQSAVMRTTSLA
TCKLLKDAGLEPVLQMTGRDRNRIAIQGEMLSAGVFGINNMLALTGDHTVVGDHPQAKGV
FDLDCVGILQTAGTLISGKDMVGNELKGSPEFYLGASVTPEYTPIEVQLLKMQKKINAGA
RFFQTQAIYDIEHMREFRRLTKDMDCKVLAGIVPLKSPGMAKFMTANVPGIFVPDDQIER
LRAAGKENWVSEGIKMAGEFIKQLKEEGLCDGVHIMAIGAEENVPAILDAAGL
>A0A135V1I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum salicis|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTAMGLSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKNE
YRDTEDSETDDAEDFVWAVDLVKYIRKNYGDYFCIGVAAYPEGHADESHPQGQSFEHDLP
YLVDKVQAGADFIMTQLFFDIKAYENFEKSLKEHPSGAFKDIILLPGLMPIQSYQMIKRT
TKLSHAKIPDNLMARLDAAKGDDEKVKHVGVDILSELVKQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDPKDEDEEAIIDDGPGIPVPVAVPAVQLNGLSPVPHPATRTLSN
GRRPSSMGSDPHNRIIVSGSASNPAYETTTAGLMASEPVNTRANTLAISEGVGAVGREAT
WDDFPNGRWGDARSPAYGEIDGYGVSLHMSVTQAMRLWGTPKTVQDINNIFIRHIKGQLA
AIPWSEEELLPESNIIQQELLELNTHGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKA
FVELFIPSSDWAGLVARLNEVTDNTICFYAANGAGDFVSSDASGGLVLEGTEASTNAVTW
GVFPGKEIITPTIIEEVSFRAWAEEAFKIWGEWAKVYGKGSESEALLERIGSEYWLVNII
HHDYVERDALWKLLSGEKET
>A0A1T1JL34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. MF4640|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPIAPHLSCIGDDKARIAELLDIYKNQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A3D4DXP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Subdoligranulum sp|TrEMBL
MTITEQFKAKRCVFSIECFPPKQTTQMDKLKDTLRQMQAMDPGFISVTFGAGGSAGGVST
AEVADYIQNELHVPTLAHLICMGNDETRAAEILDQLESVGVRDVLALRGDRSPSRPESPD
FKHASDLTSFIKWKKPGFSVHGACYPEGHPEADSLLHDVENLRIKQAAGAEHLLTQLFFD
NMHFYRFLNLARRAGITLPVSAGVMPIVKRSQIERTVSLSSASLPSEFTRMISRYQDDPA
SLYDAGIDYAVRQLRDLIEGGADGIHLYAMNDAAVAAKVYDGIRDLL
>A0A4P6YBV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium nackdongense|TrEMBL
MKVTQHIGNANGKPLFSFEIVPPQKGTNIKDLYQNIDPLMEFKPPFIDVTTSREEYVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGVDAIPHVLCGGFTKEETEYLLVDCHYLGIDNL
VALRGDPMKGEKYFEPTKGGNGYAVDLVKQIKAMNAGQFLHDTLPMQNAPDFCVGVAGYP
EKHIEAPSLEADLKRLKDKVDAGADYVVTQMFFDNQKYFKFVEAARAIGITVPIIPGIKP
VAVKRHLQLLPQVFWLDMPQDLIHDIEQAKDNAAVRQIGVEFAVQQSKELIEFGVPCVHY
YSMGKSDNIHQIASQVF
>X8H0H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. ICM51a|TrEMBL
MTLREKHQKGQFTITVELDPPKSSSAQKVFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNEGIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDHGDHPFAQSV
FEVDCMGLLNIAKTLNSGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNGA
HFVQTQPIYDLEQAKRYIDKMSEFNVPIMLGLIPLKSFKMATYLHEKVPGINLTQDILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A6I1ZH41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTNLERILTSGKFAVTAEAGPPKGTSAEVIRKKGELLRRCCDAVNVTDNQTAIVRMS
SLAGCLLLRQQGIEPVMQMVVRDRNRLALQGDVLGAVALGINNILCLSGDHQKFGNHPTA
KGVFDIDSIQLIQTLKMLRDEKKFISGEDVSGEVPVFIGAVANPFADPFEYRVSRLAKKV
KAGADFIQTQAVYDVPKFARWMEMLTERGLDKKVHILAGVIPVRSAGMARYMRDYVPGVT
VPDEIVTRMEKADNPKEEGVRIVLEIIEQLKDMPGVHGIHIMAVNWEDIVPEIVQKSGLM
PRPVV
>A0A800EW83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTQPTSSPTSDSFRHLLTNTDRFIVAVELETSRGLAMEESSSRALSLARRLAGSNPVDLI
CITDNPGGNPHIRPEVLGYELLARGQEVVINFSCKDYNRNGVESRLWSLGSLGFDNVLAL
TGDYPITGHAGGPQPVFDIDSVGLLEVMRHMNGGLEVPSRRAGGDPYTLRQTSFFPGVAI
NPYKSVESELLPQFFKLGLKLRTGGEWAVTQIGYDSRKLDELKKYAAANGMDIPMLGSVF
VLNAPAARMFNRNGIPGVTVSDDLLHLAEKHARSEDRGRAFFEEFAAKQIAVLRGIGYRG
VYLSGRLPLSRIRRVLEIETSFGADDWHDFAKEIQYQKPGEFNYYERDPGTGLCSDQVNH
RYLESKTDRALKRSRRSVPLAYKAGRAAHNLVFDRGALGFGAARWAYERVGNRSRTGKLM
HFAEQAVKIPAFGCQDCGDCSLPDIAYMCPESQCVKNQRNGPCGGSHDGICEIGDKRCIW
VKAYERTKAYGEEDGMLDRPVVFKNGALRGSSAWANAFLGRDHNAQEHARDEAGAPTSSD
ARRSAESTD
>A0A6G9Z0P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia terpenica|TrEMBL
MSFDNARGRSTPGRLSRTPQVSGTPSVVGRLGPRPDGTIPFSVEFNPPRDAANEARLWRA
AREFERMHPAFVSMTYGAGGSTRDRTARVTGQLARETTLLTVAHLTAVGHSVAELRSIMG
TYADSGIRNLLVLRGDPPGDPLGEWQRHPEGLEYAEELVRLVRGLGDFHVGVASFPQGHH
RSPDLDHDTAHLCAKLRAGAEYSITQMFFDVDDYLRLRDRVIACDPIEGAKPIIPELMPI
TSLRTVQRAEELSGRSLPPRLRERLERAGGADPDANRAAVREVGIEIATEIAQRLIDEGA
PCLHFITLNFAKATSEVLTNLGYTVTAAPVGA
>A0A7V1VYY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MIPDNQTAAARLRAVLAAGRFVVTCELECPRNASAANVERQARGYAPYVDAVNCTDNSAA
IVRMSPVAAAAIVARTGLTPLVQLTCRDRNRIALQSDILGAVAVGAAGIVAMTGDPPGTG
NHPDAKTVFDITSLELMRVARGLREGHFMSGDPVRPAPDLLVGGVENPAEGERSVSRLAA
KVEAGAELIQTQITFDVEAFARWMEQVRAAGLHERVRILAGIAPVRRPSIARYLHEHVPG
ISVPAPTLARLESAANPEAEGVRVAAEVLAAVRGIPGVAGVHLMTFGWVEGVARVVQAAG
IERTPAQGVD
>A0A6M8VL99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSDSQLSFEFFPPRSDEQVKAFGLARDRLAELQPDYMSVTFGAGGSTRSRTRETVLAIER
ETRVPAAPHISCMSEDTDNIRELLDDYSRAGVRRLVVLRGDRPSGGGSGVFDYAVDLVRF
IRQHYGDRFAIEVAGYPEHHPESPSPESDLRHLADKVRAGADGVITQYFFNAEAYFRFVD
EAHGLGITVPIVPGIMPITNYSRLARFSKMCGAEIPLWIRKRIQAWEKAGDRDSLLGFGE
QVITGLCERLLDGGAPGLHFYTLNRSAPSLRLCRNLGLGGQAARDGVRKATA
>A0A7C6SLP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp|TrEMBL
YDFLDRAISLGITCPVTPGIMPVFRADQIKRIASLCGASIPAELVIVMDKYGDNPDDMLK
AGIEYACNQMQDLIDNGVDGIHLLTMNRAKSTRKILENLNLLKK
>A0A800EZC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTSTSRRLPLVSFEFFPPRTPHASRTLWRSFKRLEPYGPRFTSVTYGAGGSTRERTHQIV
RRMLEESDIPPAAHLTCVGASRDEVDEVARDYWEAGIRHIVALRGDPPAGMDRYEPHPHG
YHYASDLIAGLKRVADFEITAAAYPEPHPESISEKADLDNLKRKIDAGATMAITQFFFQP
ELYLRFMDRARAAGIMVPIVPGVMPVVDIVSASRFAKRAGASVPDWLVARFGRAGNGTQA
RLSVAISVATEFTHRLMLEGVEQLHFYTLNRAAVVAQTCENLGIIPAEVKVVD
>A0A7V2VS74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSLRALLGAGKFVVTAEVGPLKGTDTTEIEEVAELLRGRVDAANVTDQQSSVLRLGSLAT
SHLLREKGIEPVFQMTCRDRNRLALQSDLLSAYVLGIDNVLAITGDLPALGDHPEAMPVY
DLDSVQLLWVIKRLNEGYDMMGNELAGKPNFFPGAVVNPGANTEAALELQLIKMEKKIAL
GAKFFQTQAIYDIDAFVKFMKRVEGFNIPILAGIIPLKSAGMARFMNKNVAGVFVHEELI
NKLATAEDKARTGIGIAADIIKQLKDICHGVHIMAIGWEKRVPEILDAAGL
>A0A1C5T8E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Faecalibacterium sp|TrEMBL
MKDIRELLQTRPLLFDGAMGTYYKAAPGVECEQANLTDPAGVLAVHREYLAAGADAVKTN
TFSLPRLAAAHTPGWEQLAQAGWQLAVQAAEETDAAVFADLGPAPDTEAVPAGQVYTAVA
KQFAALGARNFLFETLSSDAGLLDAVGAIKAEVPDAFVLVSFAVLPDGYTREGMYCKDLA
RRMQESGIVDAVGLNCVSAPGAMRTLAKQLGGTLPLSVMPNAGYPVVTRTQVKYQGRPEY
FARELGRLAAEGTVQILGGCCGTTPAHIAALRAELDSLPVVEKTAPAEEFSTMKKQTVEN
EDAFLRKLNGGEKVIAIELDSPRNADLTGYLEGAKKLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGLCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPGPMTVFGALNLNARNFDVELRRAKEKLENGMSGFL
TQPVLSAQAVENLKKSRETLGADAKILAGIMPVVSQRNAIFMENEINGIHVEDWIIEKFA
GLDRAQGEELGLAISLEMAKAALPYADGLYLMTPFNRVALMERLIGRLKQEVLGAY
>A0A4E9F7M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brugia malayi|TrEMBL
MDAVRDDNEGEMSPTSSTDGFVVSSSGNTSDVVIPRSCSKKWGESRTDWVANGTYVPLRD
RIKKRIANGIPFFSLEFFPPKTTNSVANFFARLDRFREGNPMFVDIAWHFGSDPGNISSE
TSSSSVAAGCLDYCGMDTMLHITCCPYTKEQSIRHLEQSKALGLKNILALRGDLPRQDEN
PVLYKYRALDLIRWIKEEYNDYFTIACAGYPAGHPEAPSYRADLLYLKAKVDAGADFIIS
QIIFDGEVFKNFLRDCREIGITVPIIPGILPIQSYESIRRVAELSQLVIPDSILTSLEPI
KNDDDAVRNFGIWHAVTLCRTLLSNGSATSIHLFTLNREASSREILQQLGLWPRSPMRAL
PWRLFGESHPVRCKEDVRPIFWSMRPKSYVFRTREWDEFPNGRWGNSSSPAFNDLKDYYL
FYLKGQPTRDEQLRMYGERLETLADIQKVFVNFITQNINENGVKVSQLPWNEQHDGIRAE
TSLIKDQLLWCNSNGFLTINSQPSINGAPSTDPFVGWGKPGGYCYQKAYLEFFTSQANAE
VLWSLLPSYSRLNCHIVNHDATIDWTNTETTMPIAVTWGVFPGSEIAQPTVVDPLSFRVW
KDEAFSAWLNWSSIYAEGTSSRCLLEKIYNEYCLVTLVDNDYPKSTIIFDCLAQLVNR
>A0A8C8C9Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
LTCAELSNGSITPAVGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTESGDHWFS
LEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYATDLVKH
IRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVR
DCRAIGITCPILPGFVFQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGIEQA
VGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHPKRKVEDV
RPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWG
EELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVNRRGVLTI
NSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVN
VHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQWAKLYEDE
SPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEQTAEQPNDE
QSDKEQPGK
>A0A6I5EUB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8356|TrEMBL
MALGTASTRTDHARTVRDMLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPKGVTYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A2E5Q7H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKKNRVTRISRELQNSIHATNRRLGQRPFPDFISLRQQVSVSFELFPPASIEMERRLWSC
IAQLAPLSPHFVSITYGAGGSTRQRTHTTVEKILTETPLTPAAHLTCVGTTRDELDEVVQ
RYWDSGVRHLVALRGDSADPGRPFASHPQGYQTAVQLVAGIRKIADFDISVGAYPEVHPD
AKSQEADLDNLKRKLDAGANRAITQYFFDVDDFFRFLDRARDVGISAPIVPGILPVTNFE
KVVEFSKKCGTTIPVWMQDLFAGLDDAPEIRQMIAATVAIEQCRLLLEKGISEFHFYTLN
RAELTRAICHALGLRDYREDSLCELKVPGQ
>A0A521X047|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKHPFLTALEERILLADGAMGTLLQSRGVPTTACLEAVVLDDADKIRRVHEDYIAAGADI
IETNTFGANRFRLARHGLERRVHEINFKAARLARDAREIHGHPVFVAGAIGPTGRMLAAV
GDVRPVEVRAALREQAEALLEGGVDLIILETFPDIAELREAILAVKECCDLPIVAQATFQ
RDGRTYGGEPPDEVANVASSLGADVAGVNCSLGPQSALEVVEQMTANTAIRVSAMPNAGL
PRFMDQRLVYPSTPDYFADYTRKLVEAGANIVGGCCGTTPEHTAAMRRALDGEWNTRGRA
PVHATSISSPAIGAPAPSDGASADTRSLREKLAAGEFVVSVELDPPRGLNPRKALEGAAH
LKALGADTINIGDSPMARVRMSAISLAVLIQQRVGIETIIHFTSRDRNLMAIQSDLLGAH
ALGIRNVIALTGDPPSTGDYARATGVWDVDSIGLIRVLKMLNDGTDWAGNSIGKGTDFFV
ACAANPTADDVGVEVDRVRRKVEAGADLLMTQQLYSADVLREFLERLGPTGLPVLVGIMP
LQSHRHAEFIHNELAGVSVPDDVRERMRLAGENGIAEGIAHARELLEQCRPYVNGTYLIP
SFGRYEVVGELVTLAKQL
>A0A6I2A0X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MNIVELIKQGKFAVTAEVGPPKGVDIQEMLETAEVMRGRVDAINATDQQSSAMRLGSLAT
CCLLKQKGLEPVFQVTCRDRNRIALQSDLLSASVLGIENVLCLTGDHVSLGDHPQAKPVF
DLDSVSLLQAAKELEQGKDLAGKELEGSPKFCLGAVVSPASEPVEPQIIKMEKKVKAGAE
FIQTQAVYEPKKFEEFMKATAHLKVPVMVGIVLLKSAGMARFMNKNVAGVNVPDNLVEEM
DEAEDRAKKSIEIAARLIKEMKSMCQGVHIMAIGWERKVPEVLDAAGL
>A0A7K3BSR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4919|TrEMBL
MALGTASTRTDRARTVRDMLASGKATYSFEFWAPKTPKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATESIVADSTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPEGLAYAAELVRLIKESGDFCVGVAAFPEMHPRSESWDQDVRHFVD
KCRAGADYAITQMFFDPESYLRLRERVSAAGCDTPIIPEVMPVTSVKQLERLGQLSNAAF
PDELKERILAAKDDPAAVRSLGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHTRA
>A0A7X4BXC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSSSIPPAGQPSALLQKLHDGEFVTTVEVHPPRGFLFERTLGSLKALMERVYVDAFNATD
VPLAQARMSAVALSVLLQRQTGVEAILHTGTRNRNVLSLHSDLIGAHALNVRNVFVFHGD
NPSIGDYPNASSLSDVTSSQLISALSRMNAGEEVAGHTLPEPTSFAIACALSPNAPHIDE
EIASLERKVEAGAHYIMTQTVFDAAPVRRLHDLLGGFPLPVVLGVLPLQSARHAEFLHNN
VPGMVIPEAIRNRLHAAGDNARAEGAAIARELIEETREMIAGVYMIPSFGRYDVVADVLA
DD
>A0A2T3ZAU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma asperellum CBS 433.97|TrEMBL
MDKITDKVAALPADAEYFSLEFFPPKTQMGFSNLRVRLQRMERALRPLFVNVTWGAGGST
AQKSIELAELCQRELGLTTCLHLTCTNMSQAMIDQALEDARALGIRNILALRGDPPRAEY
RDADEPTGSEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPYLV
DKVQAGADFIMTQLFFDIKAYEKFETTLRNHPSGAFKTIPILPGLMPIQSYAMIKRTAKL
SHAEMPEEIMTRLNAVKGDDEKVKMVGVDILSELIEQIREIKSRTPGPKGFHFYTLNLEK
SISFILERTKLIPDVPEDEEAIVDEPVPVAATGQRSIPRISVNGNVPPRQSRSHSRTARR
QSSVGSDPHNRVIVGRAATHPEWEATSTEAGVPAESINTRANTLAISEGEGALGREATWD
DFPNGRFGDARSPAYGEIDGYGVSIHMSVTQAVSLWGHPKTASDINDIFVRHIRGEISAI
PWSEEDLLPESFIIKSSLEAMNKKGWWTVASQPAVNGLPSNHATFGWGPASGFVFQKSFV
EFFIPSADWKILYDKLTSEENEELVCFYASNANGDFVSSDTTGGTGRATVNASTNAVTWG
VFPGKEIVTPTIIEEVSFRAWSEEAFDIWAEWAKVYGRGSDSEKLLNEIGQDRWLVNIIH
HDYVDTDALWRLLTN
>A0A2E3BNI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTNKPVSNLAQRLGEEFFTVTAEVTLPDSIEKEALVTRAQMLEPYCDAINITDSTGAVPH
FSNIAAASILIENDIEPIIQFSCRDRNRIAVQADVIGAHAMGVRNIFCVTGDGVQTGDHP
EAKPVFDLDSITLLTTINHLKTKGKFLSGRELDAKPDLYLGAAVNPFVPPFEQRALRLLK
KQKAGASFFQSQYCFDIERLKTFLDRLIELTKGSPPPLLVGVGPLRSARFARWLRENVPG
VVVPNHIIEKIEKYPRKEQQKAGVETCIKIVETVKTLTGVAGIHVMAYNWESSVSEIIEA
TGLSKTARNV
>A0A2W4NN54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTSARPPQRDENPAGVHLPLEPLPGHTSRGRLERILRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSISLLE
>A0A1Q9JFE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hornefia porci|TrEMBL
MNLKDLFNGEKTVFSFEIFPPKRDADINTIYTTLDQLHYLDPDFISVTYGASGSLANNST
CEIASAIKKQYCLEAAAHLTCVNSTREEIDIMLERLANAGIDNILALRGDRVPDVPPKED
FLHASDLIGYIRSSRYDFGISAACYPEGHPDSPDMIDDIRNLKRKVDAGAEHLISQLFLD
NGMFYSFLEKARIAGIDVPIEAGIMPVVNKKQIERMVTLCGATLPEKFIKMMEKFEHKPE
AMRDAGIAYATNQIVDLLAHGVDGIHLYTMNNPYIARRICQNVKTLF
>A0A317I1J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTALAAQDEAPSDPLARIAAFMKGFSIEATRPSDADIAALAPLKRCACVYLSAVPNRPAD
ESLGAAIRLRAAGFEPVPHVAVRNFADLAALDDFLARLNGEAGVTHVLVIAGDRAESGSL
RRALDAIDSGTFRRRGIRTIGIAGYPEGHPRIGGVELNRALGEKIAVAEATGLAVEIVTQ
FCFNASAILNFLARLRAFGFEHPVRIGLAGPTSLAALLRYAARCGVRTSAQALVQRSGLV
RQMFAMTTPDDLVQALADVASAGVTPHFFSFGGVRATARWARAVADGSIALKAHGGFLVE
APKSEG
>A0A2Z4AWV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blattabacterium sp.|TrEMBL
MKVTDHINKAKKSLFSFEILPPLRGHDIKNIFSTLDPLMEFNPPFVDVTYHREEFFYVEK
ENGLLQRKKVSRRPGTVGICAAIMNKYGIDAVPHLICGGFNRQMTENALIDLNFLGIDNV
LVLRGDPIKSENSFFAKKDGHKYAVELVEQVKNLNKGKYLNKTFEKKNYPLFDFCIGIAG
YPEKHLEAPNMESDLFFLKKKVEAGANYIVTQMFFDNKKYFNFVKKCRSEGIIIPIIPGI
KPISSKIQLNSLPSRFYLNIPNELVKEIEKAKDKKLIFNIGIEWAIQQSKELKNSGVKVI
HYYTMDKPENIYKIVQAIY
>A0A354NXP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MLRDRASLNPLRLRRPTVVSATSVSRWHAGVVKILRTWRQAGFYPIPVATTRDMLIFLYL
RRRSASKFMRHLMKISDILKNKRTLSFEFFPPRDEQGVERLFETIDHLKRYEPDFIDITY
GAGGSTQRLTVELCVRAYRDSGVTVMGHLTCSAQTKEMVHSVLERFESEGIENVILLRGD
PPQGEDTFVPAEDGFSHATDLIQHTKENFDFGIAAACYPEAHPESLDADSDLFYTKMKVE
HGAEFLITQLFYDNEDYYAFVDRARQSGIDVPIIPGLMPILNASQIRRITSLCGATIPAG
LDRQLERHADDNRAVRQIGIDHTLRQAQELMASDVPGIHFYVLNRRYSITEILDNLQGLS
VGVTSS
>A0A523Z0X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MIMHYTTRDRNALAVHSDMIGAHALGVRNILCLRGDPPSVGGYNDVVGVWDISAVGLMRF
LKLLNEGADWTGKPISGQADFFIGAACDPNVEPLEPQLRLMRRKAEAGAHFFMSQNVFDE
KLLERFLHKAQRLGLPIIMGVLPLHNSRHAEFLHTQVPGMRLPDAVRERMRRAGEDGGPK
EGQAMARDFIALCREKCAGIYLVPSFGRFDLVAELVAEIKS
>A0A2W4SW43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MNSERKSRLLGNGEITVSFEFFPPKNERMEEALWAAVRRLEPLNPAFVSVTYGAGGSTRE
RTHATVSRLVRETTLSPAAHLTCVGATCEEIDSIVRSYWEAGVRHIVALRGDPPGGVGTR
YEPHPGGYANAAALVA
>A0A523UHB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKTKSNLERVLKENHFAVTAELSPPQNADPEVIRRKASVLKGYVDAFNVTDGQSAVVAMA
SWAACLIGKDEGLDPIVHMTCRDRNRIALQMDILGVAALGIDNVLCLSGDPISFGNYPEA
RFVLDVNSIQLVKIVKDLRGDNRFPNGEPIPGRRPELFIGAVANPFLELPETEVNRLERK
VDAGADFIQTQSVYNIEKFERWMEIVRERGLHNKVKILAGITPLKTVGAARYMKASIAGV
DIPDELIERLRKLPTKERVSKEGIRIAVETINRLKEIEGVRGIHIMATEWEEAMREICEA
SGLCPRPRFEELAALE
>A0A419DHB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKSDGASKLKSVLAGGGFAVTAECGPPRGANAEIIHRKGEWLKSCVDAVNVTDNQTAVVR
MSSLAACLHLLELGIEPVMQMVTRDRNRIALQSDIIGAYSLGIRNMLCLSGDHQSLGSQP
EASNVFDIDSVNLVHAVRVMRDEGKDMSGFALNGAPEMFIGAAENPFADPLSYRVVRLAK
KIAAGVDFIQTQCVYDLPRFREWMRMAREEGLTEKVYILAGITPLKSAKMAQFMATKVAG
MDVPEAVIKRMAGVTGPKAVEEGLKIAIETIAELRAIPGVRGIHIMAIEAEERVPDLVKA
AGLMPRPMK
>A0A4Q6CS68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
REPRFTWSAEILPADEKHDLSAVLDQCRKLKDQGVDFFSIADGPAGSPRGGTAELTDLLR
KEFQTLAVPHLITRDRTAEKLSEFIEDYAKRGVRNILALRGDPPNDLAEGTEWNPREKGD
YTFAYELIKQIAQERPEISIGAACYPDRPNLEKEAAYLKSKQDAGARFAITQLILSVDSY
RAFVEAARKADVTMPILPGVLVPHSEEHAQQIAQRFGTRLDPKSIVGVNETLADFAQKLK
AAGAPGVHLYVLRSADVSIRTVR
>A0A2W4NP00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
LGHLEKVFLLVGVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKAEGKKICIDII
NEVKEIPGVSGIHVMAYRQEEYVAEIVDESGVLKGRRPWKREVRPDDALVAERLDRLLHD
NITETQVDMVKSAHEP
>A0A069PLW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia glathei|TrEMBL
MKPIELSFEFFPPKTQDGVEKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLEMAE
EGFEAAPHLSCIGSSKESLRAILGAYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFNIEVAAYPEYHPQSRSPRADLENFVRKVQAGANSAITQYFYNGDAYFRFVA
DARKLGVEVPIVPGIMPITNFTQLMRFSEMCGAEVPKWIARRLESFGDDREAIRNFGLDV
VTDLCRRLIDEGAPGLHFYTLNGGAATKSICERLGLDNA
>A0A7R6V7S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratiruptor sp. YY08-10|TrEMBL
MFEALVEKLRNGRYISLETTPGHLPTVENIIQKIGQYHLHEKVDAFTTTDNPLAKLKYNA
ILAAIRLQTKFHKPVIATMSMRDRNKIALQSDLLGANDFDIRAILALTGDPAKISDQPNT
KGCFEGDSTLLLDIIKCFNAGIDYAGKEFSIKPKKIYPFAVSNSYAKNSKTLQRKFAKKI
EHGAIAIITQPVFDKENITLLLELFEETRSHFQNDKAKSQLILGLFPITKLKTAQFLASH
VPGINVPRFWIDELYKAHKDGEKKEYEVGMALSRDLFETMLKMHPKVHIMTANRFEVAHE
ILT
>A0A1G2WHX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadaceae bacterium GWC2_58_13|TrEMBL
MASSHHRSQRFLEQLTQQVLIGDGAMGTLLYSRGIQLDTNFEYLNLRSPEQVSRIHGDYL
AAGARLLETNTFGANALRLAGFGLEAQTRDINLAGARLARQVAGEGAFVAGSIGPLVRPR
GEEMILPRSQKEAVLRQQMEALAEGGVDLFILETFSDLDDLELGLKIANGLGLPAIAQMA
FLQEGRTRDGVSAEAAAARLTAAGAAVLGANCGSGPRELLQVVSRMATVSKLPLSAFPNS
GFPEFVDGRYIYLATPGYFAAMGRELAAAGAGLIGGCCGTTPEHIRALAQALEGLRPAAV
RRAVKAPEVAIPRTDAVVSGSNFLSAWGCRPVVTVELDPPRGLNCDKVMAGARALTAAGV
DAISLAENPLARIRLGNIALANAIQQATGTEVIVHVTCRDRNLIGLHSELMGAHLLGIRN
VLAVTGDPASVGGESGATSVFDLNSIGLLELLNSLNNGRNLLGAELEGRTRFLLGAAFNP
NLPSMDGQLRRLNKKVAAGARFVQTQPIYSIPVMEEMLVRTADLGIPVLVGILPLVSERN
AEFLHNEVPGINLPDHVRMRMRGKQGAEGVREGMAIARELIDAGRGKAGGYYLMPPFGKV
DLALELMAFIRRPDSSA
>A0A168A3P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus macquariensis|TrEMBL
MKPDLRKAWENNVLIGDGAMGTFLYQMGFPVGISYEELNLTAPEVIKDVHRRYVEVGAQV
LESNTFSANFDKLSKYGLESKVEEINRAGVRIARDAAGPDGYVLGAVGSIRGGKRTNVST
KKLKLYFEQQITALLAEGVDGILLESFYDVEELSIALSRVRKLSDLPVVCQFAIEDVART
LDGYTMTEALHILQQEGADVIGFNCRTGPNGMMRAVESLGNQLSVPVSVFPNAGVADYVD
GEVRYTATPEYFGTMALRFADLGVRIIGGCCGTTPEHIKEISKALTGYVPSPIDKNHVVA
TPVARIVHEHTNDTVEDDREPTIVDLVKQRHTVIVELDPPRDLDINKFMLGAEALKKSGC
DALTLADNSLAVTRMSNMALGYLIQDQTGMRPLIHIACRDRNLIGTQSHLMGFDALGIDH
VLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKANFVVGAAFNP
NVKHLDKAVQRLEKKIAAGADYIMTQPVYDPKLIGAIKEATAHLDTPIFLGIMPLASGRN
AEYLHNEVPGIQLSDEVRARMVGLEGEEGRAMGVTIAKELIDEAMKHFNGIYIMTPFMFY
GMSVELTEYVWKRSGREVTPLFRS
>A0A838MJY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium|TrEMBL
MIAPNSPLFADIPGDISVSFEFFPPKSEKMETQLWDAITQLAPLDPSFVSVTYGAGGSTR
ERTHATVARIVQETALVPAAHLTCVAASKGEIAEIADQYWEAGVRHIVALRGDPPPADAG
RFTPHPDGYANAAALVAGLRARHDFEISVAAYPEVHPEAASAEADLDNLKRKLDAGATRA
ISQFFFSTDAYFRFLDKAHAAGITAPIVPGIMPVTSFAAIRRMSVNTEIPPWMEAMFEGL
DDRPGPRTLVAAVAAADLCRRLYAGGVRDFHFYTLNKAEQTYAICHLLGLRPKS
>A0A2G9MWG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilales archaeon CG11_big_fil_rev_8_21_14_0_20_33_24|TrEMBL
MTIIYEVNPPKIPDNETPDDEIKSSIEKLMQRVSDISALCDGIHVTDSVLGTKRVSALTV
GRLLKKKHPDLQITISMRVRDKDMSLIKQLTQESIELKLDGILILKGDPSKENPTDSGLI
PSQVVKELNELGYGNKMNFFLSLPSNPNFEKIQKKIAASPKGFMTQVIHSAEQVQRISNK
LKPKGLRIIPCVLLPSEKNNNSAKFLELDWSNYKENPSNFIKQIHNIAGDVLVTSPNDFT
FAKETLKKI
>A0A7X1KWH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas kielensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRALLSQYQAAGITRIVALRGDLPSGMGMASGELRHANDL
VQFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLKLPR
>A0A143Z7S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus sp. ES5|TrEMBL
MKIESKFQKKKPVLSFEIFPPKRDKAIQNIDETLAILSELNPDFISVTFGAGGSHTDNQT
VELAKRIKQQYGIDPLVHLTCLNSSKFEICELLEELKEAEIDSILALRGDKNPAVEEKQD
FRYASDLVKFIRQYGDFSISGACYPECHTESKNKIEDIAHLKEKVDSGVQHLISQLFFDN
NAFYSFREHIQIAGMHVPVEAGIMPVINKAQIERMVTLCGASLPEKFSRVMHKYEDNKEA
LFDAGMAYAINQIVDLLAHDVDGIHIYTMNNPIVAKRICDGIKNLI
>A0A0F3L967|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. KM4|TrEMBL
MASSASLNLADARALLLSPLGPVARAGSNRDAVRVSFEFFPPKTDEAEANLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIITETSLRPAAHLTCVEASRDEVDEVIEGYKTIG
VDHIVALRGDPPGGAGIGGVYQPRADGYANATELTAAINRIGGFDVTVGAYPERHPESPS
IDHDIEVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLK
RMCGACGASIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETAAAQ
>A0A1G9NFQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas pantelleriensis|TrEMBL
MNDLLRLTPLPSDERACEALASPRYELLPLADLQQAADALPAGAVVTVTCSPRHGLARTL
TASETLAAAGFRVVPHLAARLVRDRGHLAEAVARMTALGIDECFVVGGDAEAAEGDFATG
LALLEALAELPTRPSRIGIPAYPEGHPHISVGDLQRDLEAKARFADYAVTQLCFEAAPLL
AWREQQRQRGMSLPVHAGLPGVLPRKRLLGLATRLGLGPSTRVLGRQKGLIARLLRPARY
RPDTLLEALWPHLGDATQGFAGVHLYTFNQAADTRAWCEAQCRRQCAWKTSDSLSVTP
>A0A1G4KER5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea mirantina|TrEMBL
MSTIKDRYEMASSPFISLEFFPPKTEPGKRNLLARMERMTALNPLFITVTWGAGGSTADK
TLELASLAQRELNVPVCMHLTCTNTNKLVIDEALKKAKEADIRNILALRGDPPVGEDWGF
DEGCSEFSHAVDLVRYIKNQYQDEFCIGVAAYPEGHCEGEADNGLQDPKRDLPFLKEKID
AGADFVITQLFYDVEKFLDFEQVFRTEISSDIPIFPGIMPINSFQLFNRATKLSHASIPA
KILDRFPPQIQSDDNEVKSIGVQVLTEIVDEIFARTNGRIKGIHFYTLNLERAIAQIVTN
SSALSKILEEDNEDEVLDGDGDVVLEDLEMMESDENLKKRRRQSSRSSDITSNQVLIDHD
RNLAGRRQISGAPSRKVLVSISKGAGTLGKDATWDEFTNGRFGDSRSPAYGEIDGYGPSL
KVSTARAYQLWGRPDSLFDLQNLFIKYLEGSLPALPWSDLGLSPESALIQEELIQLNERG
FLSLASQPAANSCPSTDKIFGWGPRGGYIYQKAFIELFVHKQQWEMILKLKIDKMGSKVS
YYLGDSAGAFQSNLEPNSSSVVTWGVFPNSEILQTTIIEEESFKAWRDEAFSIWLEWSKL
FARNTASHTFLKQMHRDYYLISIVHHDFGDGDALWDLLLS
>A0A0D0QGS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. L_1B5_3|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPEMYATDLVALLKAEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLENDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQP
>A0A318I7V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pyrrocinia|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTDLCRRLIDAGVPGLHFYTLNAATATRTICERLAV
>A0A1H9ZMF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea wenchangensis|TrEMBL
MLASGKHTFSFEFFPPKTDEGERQLWKAIRELESLRPTFVSVTYGAGGSTRDRTVDIVER
IAHDTTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVRGDPPGDPTGEWVRHPEGV
LYAEELVRLVRQAGDFCVGVAAFPYKHPRSESIESDTDHFVRKCRAGADYAITQMFFQAD
DYLRLRDRVAAQGCDTPIIPCIMPVTQMSTIARSEQLSGAPFPPDVAARFEAVKDDPAAV
RRLGIDHGAELCQRLLDEGAPGIHFITFNRSSASREVFQRLEPATLRG
>A0A7D6ZDY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia huaxiensis|TrEMBL
MHSPAERHRPSHSRFSPIVSGGPSVVQSLRTHAGARVPFSVEFNPPRDTAGEARLWRTVR
EFERMHPAFVSMTYGAGGSTKDRTARITGMLAQQTTLLPVAHLTAVGHSISELRALVGSY
ADCGIRNILVLRGDPPGDPLGDWQRHPEGVEYAEELVRIVRDLGDFNVGVASFPQGHHRS
PDLATDTAHLIAKLRAGADYSITQMFFDVEHYLRLRDRALACDPVEGAKPIIPELMPITS
LRTVTRAEELSGRPLPRAVLERLRRAAGSGPEEDRAAVRAEGIEIATEMAQRLIDEGAPC
LHFITLNFAKATGEVLTNLGYEVTAAPLSA
>A0A849VPM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium pellucidum|TrEMBL
MSFFRQSRRPDIGHNIRVSFEFFPPKTEVMEERLWETVTRLAPLNPEFVSVTYGAGGSTR
ERTARTINRILTETDVNAAAHLTCVDATKEEVDTVVREFAAMGVKRFVALRGDPASGVGS
HYKPTPGGYENGADLVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVEKVRRAGIYIPILPGILPIHNFTQVTNFCSKAGTHIPNWLAERFE
GLENDPQTHQLVASAVAAEQVLDLVERGAQDFHFYTMNRADLAFAICHLIGIRPGSNVVE
ANLAGAAA
>A0A6I2UP39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. SMMA_5_4|TrEMBL
MTTPAISFEFFPPRNLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETLQIVSDYAAAGVHEIVALRGDAPQGQDRFVPHPEGFANSV
ELIEAIAARGDMTIRCGAYPEPHPESPDTAADVAWLKRKVDAGASSAMTQFFFDAETFFR
FRDACVAAGISAPIIPGILPIQSWSGTRRFAERCGTSVPQWACDAFEAAGKEGEGQLALD
ICVRLCQQLIQGGVDRLHFYTLNKPELVGQVCAALGIEPRAEFPRVA
>A0A0A4ACE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia typographi|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPEMYGADLVGLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMTSMFE
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGVAAV
>V9HGD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. 7_2_43FAA|TrEMBL
MNINNLFDKKEVVFSFEIFPPKQESKIDTIYNTLEELKDLKPDFISVTYGAGGSLSKNMT
CEISSIVKNKYKIEPLAHLTCINSNKNQVNSILDNLKQSGIENILALRGDIPLGYKGSNE
FDHASDLIKHIKQRGDFNIVGACYPEGHLDSKNLEEDIINLKKKQKAGATHLISQLFFDN
EYFYSFLEEKEKYNIDIPVQAGIMPVINTKQINRIVSLCGAKLPKKFIRIMNKYEFNPEA
LRDAGIAYATEQIVDLISNGVDGIHLYTMNNSYVAKRISTSIFSILDTINNCERLIN
>A0A2V0P1W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raphidocelis subcapitata|TrEMBL
MKIIDKINDKLKRGESFWSCEFFPPRTEEGVENLFERLDRIASYGPLFCDITWGAGGTTA
DVTLDIAKRMQNMVCVETMMHLTCTNMPVEKLNQALDEVRAAGIQNILALRGDPPKGQEH
FETVEGGFSCALDLVRHIRATHGDHFGIGVAGYPEAHPDAIVDDPEQMKENYWKDVHYLK
AKLDAGADFVVTQLFYEADRYIQFVKDCRSIGITAPILPGIMPVMAYGGFKRMTGFCKTA
VPAAVAEKLEAVKDDDEAVKNLNLERSVVGILEGVGLLDTANVPRSLPWRHVPGGGQRAE
ERVRPIFWSNRPKAYITRTANWDAFPNGRWGNARSAAYATLTEHPFMRRHTGSDKRRERA
AAAWGEPKSVADVAEVFVRYCSGDVGVLPWAEMEELHRESGTIKDQLVELNRGGYLTINS
QPRVNGVPSNDATYGWGRPGGYVYQKEYVEFFCAPDKLEALLQRLGDSPSVTYLAVNAKG
EMRSNTDGEGGANAVTWGVFPGKEVEQPTVVDPVSFGVWKDEAFGLWLTEWGALYEEGSP
SRKLLQRIHDTWWLVSVVDNDYVGGNLFKALGV
>A0A4D6XY31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MNFFSEYHQDIMNQKLKNIRNSIHCSFEFFPPKNSSLEENLWSSVTRLSKLKPKFFSVTY
GANSGEREKTFNIVNKIYKKTGIITAAHLTCIDSTPSELKKIAENYWNNGIKSIVALRGD
TLKKDYKHNMYALDLVILLKKIADFDISVAAYPELHPESKSSKLDILNLKKKIDAGANRA
ITQFFFNIESYLRFRENCIKSGINVEIIPGILPICNFKQLQRFSKMTNIKIPKWMFEMFH
GLDDDLVTQKIIGSSIAIEMVKKLSFEGVKNFHFYTLNQSDITYAICHILGL
>A0A2W5FPQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micavibrio aeruginosavorus|TrEMBL
MTDLTYSFEFFPPKSEKSAQELLSSVEELSRFSPKFMTVTFGTGGGSRDTTLQTLKNLQR
AANGIPFGSHLTYISHTKEELDHYTDILWNQGIRHLVALRGDMPTNLVWPLDPDAEYYQF
TSDFVEALLKRHPFDISVGAYPEKHPDAPDMQADLIALKKKCDAGATRAITQLFFDNDVY
YRFVDAAQKAGIATPIVPGLLPIRDFQKVCEFASKCQASVPQFLHEKFAGDISDNLAEDL
LSAQVEDLAKNGVDHIHFYTLNKSSVLNAVCKNFSKN
>A0A261Q601|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Siphonobacter sp. BAB-5385|TrEMBL
MKVTEYIQQANGKALFSLEIIPPLKGQSVTELFDTIEPLMEFKPPFVDVTYHREELIEKR
HPSGLIQKVPVRRRPGTVGVCAKLMERFKVDAVPHVICGGFTKDETEDFLYDLHYLGINN
VLVLRGDPEKSAGVFKPKEGGHAYATELVEQVVDMNHGRLLHEETEAQPTNFCIGVAGYP
EKHFEAPNHSNDLRYLKKKVDLGAEYIVTQMFFDNQKYFDFVKRCRKEGITVPIIPGLKP
ISTKKQLTVLPRIFHLDFPEELVHAVEACKSDKEVREVGIEFGIQQCKELLDFGVPVLHF
YTMGKSDSVQRIARAVF
>A0A2A5HDV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium|TrEMBL
MSTPKTSVSTSRRLSFEFFPPKTEAGHEKLKDVRAQLQTLSPDFFSVTYGAGGSTRDNTL
SVVQKMKQEGLDVAPHLSFGGDSTGSMQDLLKRYIEIGVNRIVALRGDMPSGTGGAQQMV
YAKELVSFIREHYGDHFQLEVAAYPEIHPEADSYDDDIRHLKAKLDAGANSAITQYFFNA
DAYFHFVDRCQQAGITQPIYPGIMPITNYKRLARFSEACGAEIPRWISKRLEGYGDDLAS
ISAFGQEVITQMCERLLTNGVPGIHFYTMNQAEPITAIVRNLGLDKEA
>A0A395MDT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium flagelliforme|TrEMBL
MHIKDMLSDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WIAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVADMCRKLLANGIHHLHFYTMNLAQATRMLLEELEWAPSAERP
LQHALPWKQSKGLRRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKTIQDIAQLFVSYLENKVESLPWSEAPLTDEADEIRDGLIE
LNKRGLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPSVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPI
ANGAVDTEPIANGTTATAVAN
>A0A014CRI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_6|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A0F5VS93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WM6386|TrEMBL
MALGTASTRTDRARTVRDMLATGKATYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNILAVR
GDPPGDPMGDWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDADVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVKAACETPVIPEIMPVTSVRMLERLPQLSNAAI
PSVLKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A2D5M3S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium|TrEMBL
MVSYAQGIDALNQSLSEVKGINVSFEFFPPKTETMEKTLWKSVERLAPLKPKYMSVTYGA
NSGERDRTHEIVKRIQSETGIAAAPHLTCVDASRDELKQIAKDYWASGIRKIVALRGDLP
EGYTEHVSYASDLVALLRDVADFDIAVAAYPEKHPEAPNSQFDLLNLKRKAEAGANQAIS
QFFFDAEVFLRFRDRAAAAGIDMDIVPGILPVTNYQTLQRFAGFTNVHVPNWLHKMYDGL
DKDDQTTRNLMGASIAMDMVKVLAKEGIRDFHFYTLNRCELSYAICHMLGVRAD
>A0A0Q5NBF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. Leaf176|TrEMBL
MKITDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARSADTAFIPTKGGHCYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNTDFKFLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDIHVPIIPGLKP
ISTLTQLNVLPKIFHIDLPEELTDALSYAKSNAEAKEIGTEAMIKQCKELMDFGVPVLHF
YTMGKPEQTKKIARAIF
>A0A656QGY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia zhejiangensis|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRASRAELKKLSPKFVSVTFGAGGSTQQGTLDTVLEMAA
EGFEAAPHLSCIGSSKDSLRAILLQYREHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQEHGDWFNIEVAAYPEFHPQSRSPKADLENFARKVKAGANSAITQYFFNADSYFKFVE
EARKLGVDVPIVPGIMPITNFSQLMRFSDMCGAEVPKWIARRLESFGDDRESIRAFGVDV
VTGLCRRLIDDGAPGLHFYTLNGAWASKTVCERLGFKSV
>A0A286GW49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenispirillum bisanense|TrEMBL
MTTAADSTLAALRAGLPIAAPCDGPIDVSFEFFPPKTDKMQESLWTCIRRLAPLRPKFVS
VTYGAGGTTRERTHETVVDIRRKTDLEPAAHLTCVGATREEVDAVARHYWEAGIRHIVAL
RGDAPEGAGGYGPHPGGYAYAADLVAGLKKVADFEVSVAAYPETHPEAQSPDADVENLKR
KVDAGATRAISQYFFNPEDFLRFRDRVRAAGITVPLVPGILPVTNFATVCKFSAACGAGI
PPWMHGLFDGLDEDPETRKLIAATLAIETCRALAAEGVGEFHFYTLNRADLTYAICHVLG
VRARAAAAATPAAV
>A0A074JBW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira permensis NBRC 106175|TrEMBL
MTVKNDIAPQGTSRSDLRISFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGST
RDRTHSSVTRIQGETGIPAAAHLTCVGHTKEEIEGIARNYWDEGIRSIVALRGDLPDAGD
KYVPTPGGYPYAVDLVEGLKRIADFDISVSAYPETHPDAPSADFEIEYLKHKIDAGANRA
ITQFFFDNEVFLRFRDKCVAAGITAPIVPGILPVTNFGSLLKFADMCGASVPKRLHWRFE
DLDEDPDTRRMVAFHEAISQVEGLMAEGVTEFHFYTLNRAELTYAICHALGIRGVAQAAA
>A0A414AZM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster bolteae|TrEMBL
MKIRDILAEGKPTLSFEVFPPKTEDAYDSVEKAAAEIAKLKPSFMSVTYGAGGGSSEYTV
GIASAIKEEYGVTPLAHLTCVSSTREKVHHVLGELRERGIENVLALRGDIPQDGSTPKEY
HYASELIREIKKAGDFCIGAACYPEGHVESANKSVDIDYLKQKVEAGCDFVTTQMFFDNS
ILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTYLPSRFMSIVDRFGDNPAAM
KQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A3S9MWP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonlabens ponticola|TrEMBL
MKITDHIKNADDTLFSFEIIPPVKGKSIQELYNNIDPLMEFKPPFIDVTTSREEYIYIEK
QGGLLEKRLTRMRPGTLGICAAIQNKYDVDTVPHLLCGGFTKQETEYLLVDCQYLKIENV
MALRGDARKEEKRFESTDGGHEFAIDLVKQIENLNQGNYLHEVIEISCDVDFCIGVAGYP
EKHEESPSLQSDLKRLKDKVDAGADYVVTQMFFDNQKYFAFVKAARKRGIEVPIIPGIKP
IATKRHLQLLPQTFHLDMPQELVEAVENCKNNKDVRQVGVEFCIEQCRELLEHDVPVLHF
YSMGKSDNIYDIARAIF
>A0A1V4ZG72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccales archaeon PtaU1.Bin124|TrEMBL
MMSNLQSVLSSGRMAVTAEIGPPKSADAETVRKLARHLKGSADAFNLTDNQTAMVRLSSI
ASGVVCLQEGVEPIVQMTCRDRNRIAMQSDALGASALGIRNILCLSGDHQCFGNQKEAKN
VYDVDSIGQLMLLRKMRDEGQVWGGDKLEKAPELFLGAAANPFADPFEHRVVRLAKKLAA
GADFIQTQSIYDVDRFERWMSQVRARGLHEKVHIIAGVMPLKSHKVALYMKNKVSGMIVP
DHIIDRMKNAADPKEEGIRMCVEQIKHLQSIEGVHGIHVMAVAWEEKVPVIVKEAGLLPR
PVV
>A0A4R0K2S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella capetownensis|TrEMBL
MRGFEVVCEVEPPTRPDLKRVRHQIGVMSPIADAFLIPDNHIGRATVSSVAVANEVQAMG
SRGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDDPAEGARTSQLTVRTMIEQARE
TSYPGCNPFQVGAATRLRAVPRWKAEADFLYVQVSYELDELLRWRDSVSLDIPVYAGVMV
LASAKMAHNLAALPQLTIPDTLIEAVERDQDAGVDHACELILSIRDSGAFDGVHLIPVSR
YRQVAARLEREL
>A0A6H3Q615|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olleya aquimaris|TrEMBL
MKVTEHIKNANGKTLFSFEIIPPKKGKSIQDLYDNIDPLMEFNPPFIDVTTSREEYIYIE
KQGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFSKEETEYLLVDCHYLGINNV
MALRGDAMSHQKYFEACDGGHQYASQLVSQIQNLNCGTYLHDVVEVDDTSNFCIGVAGYP
EKHIEAPSLQTDLMRLKEKVDAGADYVVTQMFFDNKKYFEFVDAAKKAGIHVPIIPGIKP
IAIKKHLQLLPQVFKIDLPQDLITNIEQCETNKQVRQVGIEWAIQQSKELQAAGVPVLHY
YSMGKSDNVKGIAEAVF
>A0A3M4NZS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. tomato|TrEMBL
MEVSSPMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLN
TVLQLENEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGEL
RHANDLVAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFN
ADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQ
SIQAFGEDVITQMCERLLEDGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A4Q6E3S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxellaceae bacterium|TrEMBL
YKGKGINRLVALRGDLPSGQVGLGELPYATDLVKFIREHSGDYFHIEVAAYPEMHPQATS
FEQDIKHFAEKVQAGANTAITQFFFNADSYFYFVDRLQKLGIDTPITPGIMPITNASNLI
RFADSSGAEIPRWIRKQLAAYGDDSASIRAFGHEVVVNLCERLIAGGAPSLHFYTMNQTE
PTRQLVNDLSLAV
>D4AYQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371)|TrEMBL
MHIKDKLALAEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMPREKVDDALQSAFKAGCTNILALRGDPPREKEA
WEQTEGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFLDWVKKCRQAGIKVPIIPGIMPISTYAAFIRRTNWVKCAVPKGWMEAL
EPVKNDDAAVKQIGKALVSEMCRKLLENGINHLHFYTMNLAQSTTMVLEELNLKPSTETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGKPKSVRDLSDIFVRFLEHKLDRLPWSESAITQESEIIKDDLID
LNNRGFLTINSQPAINGAKSSHPIYGWGPRNGYVYQKAYLELLISPTLIDEVVRRIESNA
DLTYHCINKDGELKTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSASRKLIQNTMDTWYLVNIVNNDFHKTHDIFDLFKGLVLKDIDTEVSGTQQATE
PAENGTHSEAPASKTEKQAVSAN
>A0A147GYF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas psychrotolerans|TrEMBL
MKPSLSFEFFPCKTEAGHEKLIATARELAGHGPEFFSCTYGAGGSTRDGTYRTVRQLNDE
VGVPTAPHLSCVGDSKAKLRELLQQYREAGINRIVALRGDLPSGMGLSGGGELRHASDLV
AFIREETGDHFHIEVAAYPETHPQARSFTDDVRNFVYKMQAGADRAVTQYFFNADCYFHF
VERVRKLGVEAPVIPGIMPITNYSKLARFSDACGAELPRWLRKQLEAYGDDTQSIQAFGE
EVMTALCERLLEGGAPGVHFYTLNQAEPCIAIWRNLGF
>A0A0R2K0X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pediococcus ethanolidurans|TrEMBL
MFPPHSKTPVDKLRPILTNLAQIHPDFISVTLGAGGTSVRNQNVKIVDFIQNQLNITAVA
HIPGLYQSKEDVRNLLQELNAHHVNNILALRGDKIAGREPIGDFNHANELVSFIKQTGDF
QVIGACYPQCHQEAANLTADIANLKRKVDAGADHLISQLFYENQCFYDFIEQVRGAGIAV
PIEAGIMPVTNKGQIERMAKISGKPLPEKFLSILNRYADNKEALRDAGIAYAVDQIVDLV
AHGVDGIHLYTMNHSKVAQRIWDATASLFQDSAAKPSVHL
>A0A231GB18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas jessenii|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLAIYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A2W5CX05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas kuykendallii|TrEMBL
MTQKKTNVSFEFFPAKTEAGHEKLLANARRLAAERPHFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDSKDDLRSLLTQYQAAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRRETGDHFHIEIAAYPEMHPQARGFEDDLANFVRKARAGADSAITQYFFNADAYF
YFVERVRKAGVDMPIVPGIMPVTNYSKLARFSDACGAELPRWMRKQLEAYGDDVQSIQAY
GEQVISAMCERLLAGGAPGLHFYTLNQAEPSLAICSNLGLGA
>A0A0N0ZRQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus|TrEMBL
MKIRDLLKARKGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRERS
VLWAKRILGLKLNALAHLTVAGQSRKEVAEVLDRFVEAGVENILALRGDPPQGERAFRPH
PEGFRYASELVAHIRTRYGEGLSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRMGIAIPILPGIMPITSYTQLRRFTEVCGASIPGPLLSRLERYQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGFKPQP
>K5CLJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides finegoldii CL09T03C10|TrEMBL
MKVIDLIHNNKKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELVKEALKCKTDAEAEQVGIEWCVAQCKELMSHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A844KBY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mediterraneibacter faecis|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPE
AMKQAGIAYATDQIIDLLANGVNNIHIYSMNKPEIAVAIMNNLSEIIKC
>A0A821V4N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
AIHKVDHPDMASYEEDLRYLKEKVDYGADFIITRLFFQPATFIKFESDCRSIGIQCRIIP
GIFPIQAYASLKNIVRLAKLDVPEEILACIEPIKYNGEAIRNFGVQKCVDLCRTLLDSGK
IHGLHFYTLNREYATIEILRKLDRWLEDPPLRALPWKTISKNYVVQKKISQPAVNGKSST
DSIFGRGIKKWLCLSKSLFRIFTSEKKIPALRAVLKKFPGVNYHFVNKSGEVNETSTEGE
QPIALIWGVFAENMSRTTFLNVDDTKAGMEDLDKEKINKLIQDASKNSKFFKQQQRREED
NRRRIEVKLSKIKSFTPFQIEQAEKSVDRYLAQLDKTRDLSRTFCHIDMDAFYAAVEMRD
NPALQHVPMAVGGESMLSTSNYLARQFGVRAAMPGFIARHLCPNLVIVRCDFEKYRADSV
KVM
>A0A072NCL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus sp. RL|TrEMBL
MTPSPTRISVELVPRSRSGLRAELEAVARHLPDVDTVNVVDLTRYSTRSWQGCALARPRY
RAIPHIRAVDLDPDRPLAMADALAAHGLDEVLIITGDAPADMSARVYDVDAVRAIRRFRR
ELPHVRVYAGLDPYRQSLARERDYLLRKLDAGACGFFTQPFFDLRLLAAYADLIPPEAEV
WWGATTVLTPASLNYWRARNHAVFPRSFQPTLEWNRAFAADLLTFARERGQHAYFMPVKT
EVRAYLEGIV
>A0A0U4BIT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium erythreum|TrEMBL
MPSHSIVEDLRDQRPCVSFEFFPPKDDAGEEVLWRTIADLEPLRPSFVSVTYGAGGTSQD
RTVRVTSRIAEESRIRAVGHLTLVGQSRSEIEAVLKQYAASGIRHVLALRGDPKGGPRAP
WETHPEGMDHAVELVELARDLGDFTVGVAAFPEGHPDAGGLEPDADVLVAKHRAGAEFAI
TQLFFRAQDYVDLVERVRSRGSDLPIVPGIMPILNFSQVARMAELSGAEIPREVLDVVEP
VQDDPAAVRARGIELATQLCRDLLAQGAPGLHFITLNRSKATREIFETLRGEGLV
>A0A165EL08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calocera cornea HHB12733|TrEMBL
MKLTEAISRHVASTSTPYYTLEFFPPRTDSGFENLLARLSRLSVVNPVGLSITWGAGGST
KQRSLDLAEATQRENPVTILHLTCTNMERAMLDDALDSAKARGIRNILALRGDPPRGEEY
WIPCDPQFQHASDLVKYIRNRHGDEFCIGVAAYPDGHSFDEDTELANLKTKVEAGAEFII
TQLFYDADGFLIWLRKVREIGIEVPVLAGVMPIQSYASFLRMTKLCASRVPPSLIASLEP
IRHDDEAVKDFGVDFATDMIRTITSTKHNGPIVQGVHFCTLNLEKSTWRILDKLGWIGTS
THVLEEGKNRLIQPDSNAPLSSSSLLITPQDAASAVAPKDSENSGTIANTTTTLPALPAN
QAATWDDFPNGRFGSADSAAFGVRDPYKNELGLTTAEVHRLWGQPETIDDLTALFLKHLR
GHSPFSTTPWSPNPIAAETKLILPHLIELTLRGNWSVASQPAVDCARSDDEVFGWGPKDG
FVFQKAFCEFFCESATLDRLREKATIVDTVKFFAGNAKGEMVTNMALGESNAVTWGVFPG
KEVMQPTVIERAAFQAWAEEAFGIWSEWALFFPPASPTRQLLERVRDERWLVSICHHDFK
NPDSLWDFLLET
>F9EC60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. oral taxon 448 str. F0400|TrEMBL
MPAPGAPHAARPPIHVNRGHNPAEDVITHVATHSDVPLMTHLTCIGYRKDNVIEIVHRFL
DMGVRRFLALRGDPPPGLVADDVVGDLPHADDLVRVIREVEAEYFDDGARHIQIAVAAYP
ADIDHGTGIEVLSAKQAAGADLAITQVFYDPDDYLALRRAALYSGVTMPILPGIIPLTDL
RRLTRLEALTGVAVPPDLARTLGRADGPAAAAAGIDATLNLASAVLDGGAPGVHLYTFNR
VRPALDVISHLRLGGILTGSTPDTAVQREVRRDYLNATPGGDRGPSGRMPGATRP
>A0A5E8BYM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprochaete ingens|TrEMBL
MKISQKLAQAHSGSQASRPTYSFEYFVPKTTQGVQNLYDRMDRMYDLGPAFIDVTWNAGG
STESPSANNLTTEIVATAQGILGLETCMHLTCTGMPKETVEAALEQAYKAGCQNILALRG
DKAEGKSDSDSDKDTFIYAKDLIRFIRNKYGDYFDICVAGYPEGHPEEPDPKVLIKYLKE
KVDAGANFVITQMFYNVDTFLSWVQQCREAGINVPIIPGIMPISTYASFLRRANWCQVDI
PKHFLEALEPIKGDDSEVREVGTQLVADMCRKMLANGITHLHFYTMNLERATIMILESLS
LLEQSPAVTPQEERPTSSSSVSSSSSLKVNNPPLPWRQSLGLTRKEESVRPIFWKNRKHS
YVARTQDWDEFPNGRWGDSRSPAYGELERYGGVMRHSSARAREIWGQPASYRELASTFVR
YINGKTSSLPWSDSPISAEVDEIKPQLIDLNTRGILTINSQPSVNGVPSNHPVHGWGPAH
GYVYQKAYLELLVPESLADKIIAQITQDPQITYYSVDNAGHLETNAPENGGPNAVTWGIY
PGHEVIQPTIVEKISFLAWKDEAFKLAHEWARCCDKDSAAQKLLNEVADQWRLINIVHND
FQSSNKIFEALAGISAF
>A0A1D9GWR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp. USMAA2-4|TrEMBL
MQDRYYSFEFFPPKTAEGLEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDTVLEIQR
EGTEAAPHLSCVGSSRESIRAILEAYRAGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFHIEVAAYPEYHPQAKSPRHDLDNFVRKVKAGADSAITQYFYNADAYFRFVD
DARAQGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A0Z8K712|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VLNELQIPTIAHLPAAYLTKEKVQSILHSLNEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARAIHQAIHSLFKHYS
>A0A660RWG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteria bacterium|TrEMBL
MEERLAQRDPGYDVGRTERSFVVTFELVPARASRGKAIDEILRFAGEAAAGGLISALSIT
DNAEGHPALSPMALGSEIKALGIDPIIHFSCKDKNRNLVESQLFVLDRSGLKNLLVLTGD
YPGYGFMGNAKPVFDLDSVQVLGMVSDMNRGFVLDSKAPYGGVKLAPMSFHAGCVVSPFK
RLESELIPQYLKLKRKVAAGASFVITQMGFDVRKFDELRRFMDREGLRVPLLGTVFIPTI
KLARILHRGEIPGCILPGRLLERMEQEAMSDDRGKGARLERAARLVSILRGIGYEGVHLS
GPGLKYSQVEWVIKRANEIGERWKLFTCQFLFPEEWKFWYFKEDP
>A0A6B2W7L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID13588|TrEMBL
MTPVVNAPTTSNNLRDVLAAGQRTFSFEFFPPKTDAGERVLWDAVRRIEAVGPTFVSVTY
GAGGSSRDRTVDVTRRIATETTLRPVAHLTAVGHTVAELRQIVGRYADAGIRDVLVLRGD
PPGDPRGPWQRHPGGLDHAADLVELVRSIGDFSIGVAAFPERHPRSLNWDDDIRHFVDKC
RAGADYAITQMFFDADDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDATFPP
ALAEQLAAAQDAPETAHRIGVDHATRLAQRLLDAGAPGLHYITLNRSTATLEIHQNTRSA
DAVPHRR
>R7Y6L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia terrae C-6|TrEMBL
MTPTAPAPSIVERLSAPHRGPVPFSVEFFPPRDAEAESRLWRAVRIFERLSPAFVSMTYG
AGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSVAELRALVGAYADQGITNILALRGDP
PGDPLGEWVAHPDGVEYAEQLVRLIDTLGDFHVGVASFPETHHRSPDIDHDTRTLVDKLR
AGAEYSITQMFFDVEHYLRLRDRVAAADPEQGSKPIIPGIMPVTSLATARRMVELSGSVI
PPDVEERFAKAAGNGAEEDRASVRAVGIDFATEMAQRLIAEGAPCLHFCSLNFAKATTEV
LGRLGVDVDAALHVSA
>D4BPE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium breve DSM 20213 = JCM 1192|TrEMBL
MFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTISKEYG
IPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQAVGEFNHASDLVSYIR
SVKPDLKVFGACYPEGHYQADTIDQDIENLKIKVDAGATHLISQLFYDNEDFYRFLDKAR
AAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRAAGILYASE
QIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A447IM02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus haematequi|TrEMBL
MPRPRISFEFFPPKTLDASFRLWETARALAPLAPDFVSVTYGAGGTTRKLTHEAVTTIHR
HYGIPVAAHLTCVEATRAETMEIVQSYADAGIREIVALRGDAPKGQDRFNPHPEGFANTV
ELIEAIAARGDMTIRVGAYPEPHPDSSGADADVAWLKRKIDAGATSAITQFFFDAETFFR
FRDKCAAAGIEAPIIPGILPIQGWAGAKRFAATCGTSVPSWAEEAFSKAAAEGPAAERAL
SEQTCVKLCRELLEGGADRLHFYTLNRPDLTLAVCGALGVEPLDLGAVA
>A0A7X2NMC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium porci|TrEMBL
MKIRDILAEDKPTLSFEVFPPKTEDAYETVEKAAKEIAGLKPSFMSVTYGAGGGTSDYTV
GIASDLQRKYGVTPLAHLTCVSSTREKVAQVLAELKKENIENILALRGDIPEDKGMPKAY
HYASELIREIKRSGDFCIGAACYPEGHVESANKAADMDYLKQKVEAGCDFVTTQMFFDNS
ILYSYLYRIREKGITVPVIAGIMPVTNARQIKRITKMSGTYLPSRFMSIVDKFGDNPNAM
KQAGIAYATDQIIDLIANGVKGIHVYSMNKPDVAMKIKENLSEIL
>A0A8B7YFH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acanthaster planci|TrEMBL
MSSAVNGSARPKKRHSDSSSSGSESSTTPLSVSRSPSPSNTPLIDRIAQRIACKDKWFSL
EFFPPRTANGAVNLLARLERMHVGGPLFCDITWHPAGNPGGETETSSITIATSAINYCGI
ETMLHMTCVNQTRIDITKYLNRAKDCGIRNILALRGDVPGDLEWQKSDSEDTFNYALDLV
RYIKKMFGDHFSICVAGYPGGHPEAESYEEDLKYLKRKVDAGADFIITQLFFKAKEFLQF
YKDCRAIGITVPIIPGVMPIQGYSSLRNLVKLSKLDIPEDILKVIEPIKDNDAAIRNYGI
HQAVTMCKEMFDSGDVHGLHIYTLNREVATIEILKRLGLWNEDPIRPRPLPWKTTANHMR
TKEDVRPIFWAARPKSYIHRTKDWDDFPNGRWGDSSSPAFGDLKDYHLFYLKSKSSKEEL
QQMWGEELACEEDVFEVFKCYLDGEPNRYGHKVKRMPWNDDELASETSRLRDRLISINKR
GILTINSQPAVNGAPSTDPVVGWGAPNGYVYQKAYLEFFTSRENAAALLDVLRDYPSVTY
HVVNHNGKEDITNTDRQQPIAVTWGAFPGAEIIQPTVVDPISFMVWKDEAFGLWKHQWGH
IYSEGSPSRQIINHIHDTFYLVNLVNNDYVQDDYRLFEVLEKMLARKEERRREEIEGPDL
DEEICSKKLKIDSQSAASTEGIPSSVVIP
>D8RDX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selaginella moellendorffii|TrEMBL
MRIVDKIKDAQRENRTIFSFEYFPPKTDEGVENLFERMDRMVMHQPAFCDITWGAGGSTS
DLTLEIVNKMQNMICVESMMHLTCTNMPVSKLDFALGNVKANGVQNILALRGDPPHGQDK
FVQVEDGFSCALDLVKHIRKKYGGYFGITVAGYPEAHPDVISGDAATQEAYEKDLAYLKE
KVDAGGDFIITQLFYDTDLFLRFVNDCREIGITCPIVPGIMPINNYKGFLRMTGFCKTKI
PADITAALEPIKDNDEAVRSFGVHLGTEMCKKILASGINAVHLYTLNMEKSAIAILQNLG
LIDISQVRRSLPWRPPTNVRRTREDVRPIFWANRPKSYISRTTAWDQYPSGRWGDSRSPA
YGALTDYQFLRRRSRNKKIQEEWVVPLSSVEDIAEKFANYCAGKLKSFPWSELEGLQLET
KKINSELVKINKDGFLTINSQPAVNGEKSDSPAVGWGGPGGYVYQKAYVEFFCSPEKLEK
LIRKAEEFPSLTYIAVNSVGETKSNVGPGDVNAVTWGVFPAKEVIQPTVVDPISFMSWKD
EAFQGWEDEWASLYKAKDDPAKKILLEIKESYYLVSLVDNDYIGGDLFAFFSGI
>A0A178EWV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton rubrum|TrEMBL
MHIKDKLALAEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMPRERVDDALQSAFKAGCTNILALRGDPPREKEA
WEQTEGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFLDWVKKCRQAGIKVPIIPGIMPISTYAAFIRRTNWVKCAVPKGWMEAL
EPVKNDDAAVKQIGKALVSEMCRKLLENGINHLHFYTMNLAQSTTMVLEELNLKPSTETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSVRDLSDIFVRFLEHKLDRLPWSESAITQESEIIKDDLID
LNNRGFLTINSQPAINGAKSSHPIYGWGPRNGYVYQKAYLELLISPALIDEVVRRIESNA
DLTYHCINKDGELKTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSASRKLIQNTMDTWYLVNIVNNDFHKTHDIFDLFKGLVLKDIDTEVSGTQQATE
PAENGTHSEDPASKSEKQAVSAN
>A0A1Y5ICU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ostreococcus tauri|TrEMBL
MSSLVTPRQAGSPSVSFEFFPPKSEAMADRLWETVERLEPMTPNFVSVTYGAGGSTRERT
HDTVRRIAQQTHLRPAGHLTCVSATKDEVLSVAEDYWDAGVRHIVALRGDPPSGMGEKFE
QHPGGFRDSIDLIEGIRAHRPDLGRCFEISVSCYPELHPESQGWDAEIAFLKAKQDAGAD
RAITQFFFEPEIYLNFLEKARAGGVTMPIVPGIMLQPNFKGLKRISKLCGASLPTWLHEL
YQGLEEDQETRELVTANVAADLCRKLSDEGVSDFHFYTLNRAGLALSTCRLLGLKPKPVE
AA
>A0A7R6VL37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratiruptor sp. YY09-18|TrEMBL
MFEELLHKLRNGRYISLETTPGHLPTINNIIEKIDQRNLYKKVDAFTTTDNPLAKLKYNA
IMAAMRLQEKFKKPVIATMSMRDRNKLALQSDLLGANDFDVRAILALTGDPAKISDQPNT
KGCFEGDSTLLLDIIKCFNAGIDYAGREFSIKPKKIYPFAVSNAYAKNPKTLQKRLRKKI
EHGALGVITQPVFDIENVKNLLAMFDEVRNEFEGERQNAQLILGLFPITKLKTAQFLASH
VPGINVPRFWIDELYKAHKDGEEKEYDVGFNLSKELFEEILNIHPKIHLMTANRFEVAHA
LLYS
>A0A6H2FCH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae endosymbiont of Donacia tomentosa|TrEMBL
MNYFDINKQKYISKYNNNQLSSKINISFEIFPPNENKNNSFIFWEFINTLIKFKPKFISV
TYKNTNFSYNNNTFNIIKKIKKITNIELVPHLTCINMNNDQLYNIAKKYWDIGIRHIIAL
RGDKNFNAKNLQNNNNMIYASDLVYFLKKIANFNISVAAYPEMHPESKNITEDLNNLKRK
IDAGATKAITQFFFNIETYLRFRDLCILKGININIIPGILPIINLKQLKKFINMTNITIP
PHIGNIFRKIPPQNTNIPKLLGIIITLNMIQKLKSEGVCDFHFYTLNQPDIIHAICLYLD
II
>A0A3D9YZC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylovirgula ligni|TrEMBL
MALADFSEPQPRASRRICSGINVSFEFFPPQTEEMERTLWNSIERLAPLAPEFVSVTYGA
GGATRERTHATVARLAGETAIKPAAHLTCVGATCAEVDEIARAYWEIGVRHIVALRGDPP
GGVVGRFHPHPGGYANSTALVTGLKRLADFEITVSAYPEGHPESASVDQDIDVLKAKIDA
GATRAITQFFFENEVYFRFLDKVRDRGIEIPIIPGIVPVQNFRQTARFAERAGATVPGWL
AERFEGLDDDPTTRRLIAATVAAEQVFDLVDAGIDHFHFYTMNRADLVYAICHLLGLRPT
AETKVV
>A0A4R5KVF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter terricola|TrEMBL
MSPPSLIDTHPNLTGAAPVALSYELFPPRTPAAAASLWTTIGELEATDPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPEELAGIIGELLDNGVRGILALRGDLPKD
SGQPVAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSVEHDVEVLL
AKQRSGADFAITQVFFHAEQYTDLISRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAPELIERLAAADTDAERRRIGVRATVDLANAALDAGAPGIHLYTFNEQACALDVLDKLA
LPRPARPASRLHAIARRQELVS
>A0A1W5CSJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lasallia pustulata|TrEMBL
MHIRDKLAEAERRHRPMFSFEFFPPKTAQGVQNLYDRMDRMHDLGPSFIDVTWGAGGRLS
HLTCEMVNVAQTVYGLETCMHLTCTDMEKEKVDGALKEAYKAGCTNILALRGDPPREKEK
WTAVEGGFRYAKDLIKYIKEKYGDHFDIGVAGYPEGCEDQQDPEILIDHLKEKVDAGGTF
IVTQMFYDVDIFLSWVARCRAKGITVPIVPGIMPIQTHAAFLRRASWSNCHIPQKWSDAL
DPVKNDDAAVRQVGKDLVAGMCQKILDAGIMHLHFYTMNLAQATRMVLEELGLATPDGTP
SKALPWRQSLGLNRREEDVRPIFWKNRNKSYVVRTQDWDEFPNGRWGDSRSPAFGELDAY
GIGLKGTNEQNIKLWGEPRSVRDVADIFIRFLNDEIKSLPWSESPISSEANAIKPELVDL
NRRGFLTINSQPSVNGAKSSDPTYGWGPRGGYVYQKAYLELLISPQLIAELIARMRKDPN
ITYYAVNKAGDLRTNAANDGPNAVTWGVFPGKEILQPTIVETISFLAWKDEAFRLGSDWA
RCHHVSSPSRHLIDNIMENWYLVNIVHNDFHQTHGIFPLFDGLNVKEINQSPESTTNGVH
PHDHNITNGVNGSLTKAIPEHLRN
>F4HJB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrococcus sp. (strain NA2)|TrEMBL
MRVPGCPKDLLNGPCGGALNGICEVDGRRCPWVEVVKRLELLDGASLLMEHPIIVEMEKS
TPREVKIKDSEFIKALEKNKAISVEFPLRLFERGVREFEKRGYLFTIPDNPLGYPHISPT
ALATWLKLQGFQVMPHITGKDRNALAIAAEIRTAIELDFEGVLLTTGDWPGFLLHTKPVF
DLDSANMIKLAKLMFSGIMPTGETLNIKERPFIAATMNPSYSVKLEGKRLARKVIAGADL
IFTQVVANVKVVRRIPEIIAESLKYSGREIPVIVSLLYPITEELEGLLRKMGVETGSKFE
DIVEEVSTLELGGINLIIFDDSSWEEKLNEALDLIKESLGGGK
>A0A1X7HJV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus uliginis N3/975|TrEMBL
MRPDLRQAWGNKVLIGDGAMGTFLYQKGFPVGISYEELNLTSPEVIGDVHRQYIEAGAQV
LESNTFSANYDKLSKYGLESRVDEINRAGVRIAREAAGKDGYVVGAIGSIRGGKRNNIST
DELKRHFEQQIHSLLSEGVDGIVLETFYDVEEMLLALSQVRKVSDMPVISQFAVEDIART
LDGHTMTEAFRIVSQEGADVFGFNCRTGPNGMLRALETLQGVKTLPASVFPNAGIADYVD
GEYRYGASPEYFGKMAVQFADMGARIIGGCCGTTPAHIAEISSALTNYIPSPLPEPSMED
VDRDRIVLHEHPEQEQGMEQSGEPTLVDLVKERHTVIVELDPPRDLDITKFMKGAEALKR
AGVDALTMADNSLAVTRMSNMALGHLVHSRTGLRPLIHIACRDRNLIGTQSHMMGFDALG
IDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGVAFSGKPLKQKAKFVVGAA
FNPNVRHLDKAVQRLEKKIASGADYVMTQPVYDPELIVKLREATKHLDIPIFIGIMPLAS
GRNAEYLHNEVPGIQLSDEVRERMAGLEGEEGRSMGVKIGKELLDVAAEHFKGIYLMTPF
MFYEMTAQLTEYVWELSDRRLSPLFH
>A0A6I2LG46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter sp. MDW-2|TrEMBL
MKLSVTRSDLDETIGGLVGNFSIEALPKDTQKLDDLRNHLPAGTRVYVAYTSGSTSEIVE
AAEKLRHHGMEPVPHIPARRFSSHDELRDFLGKLAARAAVKQVLLVGGDTTRPEGPYAAS
LDVLKTGMLEGHGIEAVGLAGHPEGHPSVSRDALRGALIDKCDYATKAGLEVSLVTQFLF
DTDKLFAWHADFVEQTAPGIPVDVGLPGLAKMTTLMRFAKDCGVGASLGMLTRHAGRAFK
LATSFSPEATLVDLAGGVRAAGRPLFRSVHFYPFGSFERTAEWLRGLQSQGPTRSKKHLA
EAL
>A0A7K1SRG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter arboris|TrEMBL
MKITDHIKNANGKTLFSFELLPPIKGHGIQGIFDAIDPLMELNPPFIDVTSLREDSFYKE
RDNGLLEKVTYRKRPGTVAVCAAIMNRYKVDAVPHLLCGGFTKEETEYALIDLQFLGIDN
VLVLRGDARKGDAGFIPTPGGHTYATELLEQVVNMNNGIYLHEDHESFKTDFCVGIAAYP
EKHFEAPNLKTDFQFLKKKVDLGADFMVTQMFFDNNKYREFVKCCRENGINIPIIPGLKP
LTTAKQLINLPKIFHIDIPEDLSDAVQACKNDKEVREVGIEWMINQCKELKEIGAPVLHF
YTMGNAEPTKRIAKAVF
>A0A078KLB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] cellulosi|TrEMBL
MKNIREYLQNEILIADGAAGTYISSLTGRISGPCEMLNITSADTVLRMHKQYVKAGAKLI
LTNTFSASVAGNSIGGDFDTTSAIIKEGVKIASMAAQDNAYVAADIGPLPETMFDSAVIS
EEYRRIVDTFLASDVNIFVFETFSNSVYPIKFSRYIKNKNPEAFIIISFAVMPDGYSREN
ISGQRLIDEVAEAQCADAVGFNCCCGPSHLLNYAQTVDFRGMVPVIMPNAGYPQRESGDL
TIQESDVTYSGSPSYFASRLSSAASCGFKIIGGCCGTTPRHIAMLSDAVSKASRGCGNSL
SVHEVQKPIRRTLNTFSDTLLHENRKTVVVELEPPFNADISKLENAAKVLKDLNVDAITV
ADSPMARARADSLATAARLKRTIGIEVIPHLCCRDKNLNAIKSSLISAYIEGIRNILAVT
GDPIPDTDRALVKGVFNLNSESLCRYIRSLNSDIFSGDEIFYGCAFNVNAKNPKMELKRL
EKKLDAGASFVLTQPVFTDDAAEALKEAKNKGVKVIAGLVTPVNYKNAVFLANEMPGFNI
PEKFLKRFSPDMTREQGENEGIAITIEIARKIAHIADGFYFVVPFNRVNVTKRVIEALRA
DGII
>A0A1Y4A6Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. An322|TrEMBL
MKVIELIKSSEKTAFSFEILPPLKGTGIEKVYETIDLLREFDPKYINITTHRSEYVYTEL
GNGLFERKRIRRRPGTVAVAAAIQNKYGIPVVPHVLCSGFTREDIEYMLLDLQFLGITDL
LVLRGDKAKHQSVFTPEEGGYSHAIELEEQINDFNQGIFVDGSPIKQPVHPFGYGVACYP
EKHEESPNIEQDIYWLKKKIEKGAQYAVTQLFYDNQKYFTFVDRLRSEGINVPIIPGIKP
FGKLSQLSVIPKTFKVDLPQELVSEAMKCKTDAEAAEVGVEWCVNQCRELMSHGVPSIHF
YTVGAAQSVSRVAKAIY
>U1K4Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas marina DSM 17587|TrEMBL
MALSLQEKIEDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVVIYDIQDE
SSRTNQARPFPFKQTVDPREYSKLLKDLSRLDVITYKSVAQRGVAEFKEWLDETKNEFDL
KNVVLVGSPSSEGDIKLSLPDAYKTLAEQSDDFFLGGVTIAERHASKRNEHERLIEKTTQ
GCQFFISQAVYNAQATIDLITSYARTCKAQGVTPKRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDSILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKATMELNLAEKQIA
>A0A165EPC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exidia glandulosa HHB12029|TrEMBL
MKLTDKINNRLRSTPYYTLEFFPPKTEQGFANLLTRIHRLSQFQPLAVSITWGAGGSTKD
RSLELASICQSEHGTETILHLTCTNVESGTVQSVLKAAKDAGIQNILALRGDPPRGAEYW
IPTDPQFNHASDLVAAIRSSPEFSQHFCVGVAAYPDGHPDQEVDEERELANLKRKVDAGA
DFIVTQLFYDVDAFFAWERKVRAKGITVPIIPGIMPIQNYPSFLRVVKLTGSKVPDAVHK
ALEPIRHDDAKVKDYGVMLATSMVQRLTNSGVVKGVHFCTLNLELSVRKVLERLQWTVSS
PIPPVNKLIDDSTQAASKSEPEAHLLITPESAVGHLTVHPPSDTTNVGKGELNDPSTWDE
YPNGRFGDAKSPAYGGVEPWDSTLASSHAEAIAKWGNPKTEADLTALFLAHLNGHINGTP
FWESPLSPESRLILPHLRRMTARGWWTVGSQPAADAVRSDDPILGWGPVNGYVFQKAFVE
FFASREDVDWLERSAKTKSGGLVTYFAGNAEGEWATNMLDESGNAVTWGVFPGQEIAQST
IIERDSFLAWKEEAFRIWAEWSQFYPPESPERTLLEQMRQERWLISIVHHDFKDPNGLWH
FWLDGRESSNGSDS
>A0A3D5YQ19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseriales bacterium|TrEMBL
MRVIDHLKAATKTLFSYEIVPPVRGSATNISEIFAIIEQLLPYDPKWINVTTHASSLLYV
EKSDGSIIKRVHKKRPGTMGICGVIQNKYGIDAVAHVLCQGFSQQETEDALIELNYMGIE
NILALKGDNLNYNRKLDEGERSNKYAVDLVKQVAKMRQGLFLGDTEYPALDFCMGVASYP
EKHFEAANQELNIEYLKQKVAAGAEYVITQMFFDNQKYFAFVKACRQAGITVPIIPGIKV
LKSANQINSLPRLFHVDLPHELVAQLLAAPQNAQQIGLDWAKSQVRELIAAGVPCVHFFL
MNDVSSVLDVIDEYK
>F6IJG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. PP1Y|TrEMBL
MTAAIRPADAPLFGVQPGDISVSFEFFPPKTEKMEMQLWEAITQLAPLHPSFVSVTYGAG
GSTRERTHATVSRIIRETDLVPAAHLTCVAASKAQIDEIVDRYWEAGVRHIVALRGDPPP
ADGSIFVPHPEGYANAADLVAGIKARHDFDISVAAYPEIHPEATSAETDLDNLKRKLDAG
ASRAITQFFFSTDAYFRFLDKALAAGITAPILPGIMPVTSFAAIRRMSGNTEIPAWLEAM
FEGLDDRPGPRALVAAVAAADLCKRLYDGGVRDFHFYTLNRAEQAYAICQLLGLRPKEIG
>A0A435VNP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.001.02.1.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQAPTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYIDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAEQSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>G7Q5P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio carbinoliphilus subsp. oakridgensis|TrEMBL
MRIGELIEAKRPFVSLEFFPPKEREAWAGFFDVVERLLPVRPLFVSVTYGAGGSTHAHTL
EIVSRLKTAYGLEPMAHLTCVGASREKIRGFLDGLAAAGVDNVLALRGDPPKGQEQFVPD
SEDFQHASDLVAFIRREYPALAIGVAGYPECHPEAPSARADLDFLRQKIALGGDFTVTQL
FFDNDCYFAFVDKVRGMGITVPIVPGVLPVMSLASVKRLSSLCGASLPPAYLAALEAADA
AGGPAAVAEVGIAHARKQAQDLIDRGAPGVHLYTLNKAEAVLSIVSGLTM
>X0YKB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSFQKKLLSGDFVVLAEFHPPKGVDVSELVSNIIRVKGRVNGVIVPEMAHAVMRMSALGG
AALMQQHGMETIMQISSRDRNRLALQGDILAAYMLGVKNLLVVPGEEIVYGDHIDAKPIA
DIDE
>A0A6M1S307|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium daejeonense|TrEMBL
MARNDHNEQAGSQLRISFEFFPPKSEEMEGQLWATVDELSRWNPDFVSVTYGAGGTTRAP
TLSTVRRLISETTLPTASHLTCVGATKDEVRHVVDEFRAVGVRHFVALRGDPQGGMGTAY
QPHPGGFANAAELVAGLREMGDFEISVSAYPEKHPESRDDAADIDMLKRKVDAGAHRALT
QFFFDNDIFERYLERVRAAGITIPIVPGIMPIQNLTQLKRFASMCGSSVPSFLDDRFSGL
EDQPQARAEVAAEVAAEQIEDLVRRGIGDFHLYTMNRTPLVNATLANVGLKPSVQAVAGA
AA
>A0A7V7SAI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus luti|TrEMBL
MKLLDLLSKGTVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRTAVKLAKASVTEKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEALKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSSAYFEAMAPKFIEQGVRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEEAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>X0ZEQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MRNGLCGGATPDHCEVDASRPCTWYVIYDRAEKLGRLDTLLEINAPIDGSRTGHEQWLDM
IRVWRKRGEGPHPVDFLFKRDKFKREWNAYFYALRQPDWWQGDSVYHPPAYAEPISLLEA
TLRTGAFVTTAEIAPPLDASREGIYKKASMLRPYVSAANFTDNASATVRMSSIASSKICL
DAGLEPVMQIQARDRSRIVVESDAVGAAGMDIRNILCLSGDHHRFGLSPIAKPDQFDLDA
IQMLWVLRRIRDEGKYLDGRKLKTRPQWFLGTAASPFGAPPRFEAIRAEKKINAGAQFIQ
TQPIFDYDRFTDWLEALDKRNLLDWVYILAGLVPLKSARAAHFMDEEVPGVVLTPEIIKR
MDNAGDKAAMQQEGVAIALELIERIKNTPGLSGMHIMAVHWESIVPRLVEEAGLPRPVIR
ELAEPALAPVMAEERPHRATHAA
>A0A8H9LUC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas hamiltonii|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAACNPRFFSVTYGAGGSTQARTRDIVR
TVSESGITTAPHLSCIGSEKAQLRDLLAQYQAEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPSLDKDVENFARKMNAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAF
GTEVVTRLCERLLDGGAPGLHFYTLNQAAPVMKVVDNLT
>X1IMP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MHNVLCLTGDSIDVGDHKEAKPVFDLESAQLIHLVHTLNSGTDMVGNELNGGTDFCIGTT
ATPSADPLEPQLVKVQKKLEAGIDFIQTQAVYELEELKKFVEFVRKHDEKVKVLLGIVPV
TGAKMAQYMNENVPGIFVPQYMIDELAQAPKGTGINKGIEIAGRLIKKAKEEKLCDGTHI
MFIGKEERVPEVLEAAELL
>X1AQU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MQVINVLKKADKPVFSLEITPPEKGKSIQGIFDTIDMFKEFKPHFINVTYHQQKVVYNSN
VL
>X1U8J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MIMESIKKSKFEKNLRSGKFAVTCEIGPPKGAEVEEIKEAAEYLKDVADGINVTDLQSSV
MRLGSLTTCSLLKEWGLDPIFQVTCRDRNRLALQSDLLSAYVMGIRNVLALTGDYTTIGD
HPQAEPVFDIDSVQLLWTIKNLEEGKDLAGKELTQKPSFFKGAVVNPGADTEASYELQII
KMKKKIDQGAQFFQTQAIFDAEVFKRFMERVHKENIDVPILAGIILLKSE
>X1MDI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKAGTNLEKVLESGRFAVTAEAGPPKGASAAVIQRKGELLRPCCDAINVTDNQTAIVRMS
SLAGCVLLKQLGADPVMQMVCRDRNRIAIQSDVLGAVALGIGNILCLSGDHQKFGNHPTA
KNVFDIDSIQLIQAL
>X0WKB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKNSSNLARVLEAGHFAVTVEIGPPMDCDGTKVTEKAKLLKGLADAYNITDNQTAVVRMS
SIAACVLIMREGLEPVMQMTCRDRNRLAIQADILGACALGIKNCLCIVGDHQSFGAAGRL
KGHPGAKNVYDVDSTQLLSILKGMRDDGLQEGGDPIEVRPPLFIGAAWTPLGDPVDIRPL
RLKKKAEAGADFIQTQGVYDVARFKEQMKTVCDMGL
>A0A3M7GCD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMSYDAEIFIEWAKKVRAAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAQLFVKYMSGKVETLPWSEQPISPESNVL
TNDLVNLNSRGLLTINSQPAVDGMKSSHPVYGWGPNNGYVYQKAYLEVLIPPSLIAELIR
RMDANPDITYYAVNNSGELKTNAPQDGGPNAVTWGVFPGKEIVQPTIVETISFLAWRDEF
YHLGSEWAKCYDEGSQSKNLIKEITESWYLVNIVDNDFRNMRGIFPLFDGLKVDGVEPTA
AAVNGVAVNGEAYKGDVEKKEGARKPEVNGVPDGNNAVNHADGPAVNGQVKN
>A0A5Q3HGW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp. Pch-P|TrEMBL
MNLPLSFEFFPPKTPEGAEKLRVTRQALYAHKPEFCSVTFGAGGSTQDGTFGTVKEILDE
GVAAACHFSCVGATKATVREQLATLRAMGVKRLVALRGDLPSGYGAGGEFHYASDLVAFI
REETGDAFHIEVAAYPEIHPQAKSADADLQAFVKKVNAGANSAITQYFFNPDAYFRFVDD
AQALGVDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVI
TGLCEQLYAAGVPGIHFYTMNQAAATTEIIRRLNRA
>A0A140K736|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stanieria sp. NIES-3757|TrEMBL
MSNRFRSAVAAKEFLITAEVTPPKGGNPARMLKMAEQLKGRVHAVNVTDGSRAVLRMSSL
AASVILLQQGIEPICQIACRDRNCIGLQADLMGAYALGIRNVLALTGDPVKAGDHQKAKS
VFELEAVRLLKVIGQLNNGLDFNDKPLPDEPLDLFAGAAVDPQSKSWSGLQSRFERKIAA
GAQFFQSQMITDFEKLDKFMTQIASISDKPILAGIFLLKSAKNADFINRYVPGVNIPQSI
IDRLAQASEPLQEGVKIAAEQVKLAQQTCHGVHLMAVKREDLIPQILDLAEVKPLDYSS
>A0A5C2M7G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosynechococcus sp. CL-1|TrEMBL
MSVSRFQAACEQGEFLITAEVCPPKGRDASTMLRQAAHLKGRVHAVNVTDGSRAVLRMSS
WAAAYLLQQQGFEPICQIACRDRNRIALQADLMGIAALGLHNILALTGDPVKAGDHPQAK
PVFDLESVRLLRIIAQLNQGVDSEDRPLPDGATQFFAGAAVDPQSASWSGLQQRFERKLA
AGAQFFQTQLITDFERLAKFMDQIAAGCGRPILAGIFLLKSAKNALFINRAVPGASIPQH
LIDRLAAAADPLDEGITIAAEQVQQARELCQGVHLMAVRREDLIPEILNRAGIAPLSASP
APRAKTPHSL
>E4RTZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leadbetterella byssophila (strain DSM 17132 / JCM 16389 / KACC 11308 / NBRC 106382 / 4M15)|TrEMBL
MAKVTEHIAASKGETLFSIEIIPPMKGGKIDELMNDISPLMELKPKFVDVTYHREEYLLK
TKQDGSTVEVKTRKRPGTVGLCATLMHRFDTEPVPHILCGGFTKDDTEDLLIDLNYLGIK
NVMALRGDHAKPFTSFKPKKGGHHYASELITQIKDMNDGKYLHETSEYLNNSDFCIGAAA
YPEKHFEAATAEEDFEHLKRKVEAGAEYLVTQMFFDNKKYIDFVEKCKANGIHVPIIPGL
KILSTKKQLEILPKIFYLDIPEEFAQAVKSCKDDKEVRQVGIDWCIQQCKELKSYGVPAL
HFYTMSKSTTTLAVAKEIF
>A0A0M9VSR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escovopsis weberi|TrEMBL
MHIKAILDDSKKASQPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLDKVNDALQKAYKAGCTNILALRGDPPRDQEK
WTAAEGGFTYARDLVRHIRDSYGDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGAGF
IVTQMFYDADNFLRWVAKVRARGITVPILPGIMPIATYASFWRRANHMQCKIPQDWMDRL
EPVKNDDVAVREIGKTLVADMCRKLLANGIHHLHFYTMNLAQATRMVLEELNWAPSPERP
LKQALPWKQSKGLGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPASLAELAGIFLKYITNELDSLPWCESPLTLESGPIKDELVS
LNKRGILTINSQPAVDGVRSNDPVHGWGPANGFVYQKAYLEFLLPPHLLPELVGRIDERP
TITYYAVTKDGELRSNAPSDGPNAVTWGVFPGKEIVQPTIVEAISFLAWRDEAFRLGVDW
AHCFEASTPSRALLDNIMKDWYLVNIVNNDFHESQTIFELLRGLEAIEEAAPAA
>N1VX69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira terpstrae serovar Hualin str. LT 11-33 = ATCC 700639|TrEMBL
MTKILLEVVPRDIDTLLSEVNFVKNNFSQISGINIPDLLRFETRSWVAASEIKNIFPNVI
PHLRAIDFDLDNCGDIIEYLQNNQVSSVVVIKGDPPTDMSKRVYPTTSIKMIKKLKKEIS
HLKVYAAVDQYRVGIKDEFDYIEMKKDAGADGFLTQPFFDLRLIDIFTEKLRGMEVYIGI
SPVVTEKSQSYWESRNRAYFPKDFKLTMDWNVQFAKEVIAYCSQNELNMYLMPIRLNLEA
YLNNLFK
>A0A3S4SUP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces slackii|TrEMBL
MAHPQPPHSPPAPVAATVRPTLSMELFPPRSGPAAAATWGRIDTLLSTSPDFVSVTYRPR
FVTDPRDDEGGAGVRVVREHNPAEDVVAHVLATSRVPLMAHLTCIGYRKRDVVEIVTLFL
RMGVRRFLALRGDPPAGTAADELAGELAHADDLVRVIREVEAEYFDDGRQHVTVAVAAYP
ATSDHAQAIEVLAAKQDAGADMAITQVFYDSQDYAALLRGATYAGITMPILPGLIPLTDL
GRLTRLEALTGVRVPAHLRDALGSASGARLVGRGLDATLTLATELLAEGAPGLHLYTFNR
TRPALDVVSHLRLGGILTGSPPDPQMREAIERGYLQATPGGMPAFLQEAHSPLSPPSASR
PGHPGTASLSVSTSTVKETV
>A0A3C0YPA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MAIIAQMAVNDQNETLYGDKIDYALAKVAEFEQVAAVGLNCSIGPAEMLEVLPLIKNATS
KPIALQPNAGLPQNIDGRTVYMCTPEYMAEYAKRFYEKGVKIIGGCCGTTPAHIKEMVKT
VRPLHKADLSSAVIELRSPEPTHISLQKPVELKDKSKFGAKLVSGEKIYSVEISPPKGTN
VSALIEKVKLCQQHGIDAVNIPDGPRASSRLSAMITAIKINQLCPNIETILHFCCRDRNI
IAMQSDLLGIQAVDLKNVLIITGDPPKLGEYPDATAVFDLDSIALTKVVSNLNRGLDIAG
NNLPSKTALVTG
>A0A6S4UKJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDTIDKVLHFSGKARDIQDFEHFLKQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHAYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKHARHTDR
VYLRCALQILICKKLGFAGIHLSACHKPEEQMLLESYIKQYRHLELEALEELWNSLWQVT
TGKEFAPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGLGRFIFKASFWENTLVAK
LLLKTEVLSKHSLVGCETCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKEKLIPTVPIETRGTSSWKNWYLATEA
>A0A353T7A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MAVTKKRLSKALKEKNGFAVVAELVGGANFNYAPIKKFLAAHSQAGGKDIPSEFNFVGIT
NPQSPGGVANIEPADVHRFAVANNLLGELDFIPHISCKDSNKDGIISLLAAHKAAGVESF
LALTGDKPATSKGVFELESVGLLNLTSYMNDEAVIKAKPDTLNSVPKFFAGAAVSPFKYN
EESQMQQYFKMEKKISSGAEFLITQVGWDWKKSVELMKYLADAKINVPVIGNVYLLSTIT
PAPRLMHDIKLPGCFVSDELFAKVCSESVDEHIERAAQQIAMYKSIGAAGVDIGGVHDYE
MFVKLLKRAAQIGDNWQQFKDNLCWPAKKAFYLYDDAGKRVELSKTKKTFGHRVFNCFHA
AILDPQYKGFHWLKKIMKFLGADKGKGFCYKSFNTFEKSSKYLMFDCEECGDCFLPENFG
LCTIGGCEKGMDNAPCGDSTAEGKCGNNLDRICIGDRIYKAAAAEKAGLEKLRKIINKPR
NPALEHTASILNYLFGKDHTLRSPLIGIAELVHASIPKTGEIMAKLHSLGDDWDTKPSGE
LDYIKALIESQATDGADYIAVNIDQFGESNPAFAVELMKKYVMLVRKYGKGVPVCIDSSS
DDVLKAGLKQWYDTNENVKPPLINSIKVYTIENMMPLKKHFDYKFIGLLISEGKSGSIIE
TESVDDLHNLAKTIFAAAKKYGFKAEEIFFDSTVFPLAIDMPMMPGTASYTHRTFNTIKR
IKTDPILKGCHFSLGVTNSVRDLPGRKIGVARAYVEVAMRFGLDAGIINVSHQFGVKPAD
ADLVKLVEAFANMDGSNEKQNEAMMLMGDFCSKNRKASV
>A0A419E5Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MPIFTPGRRWQPAYSPFKKESLGSALMEDIEYIIKGPLFGCRMCGNCMLQETAFICPMEC
PKGLRNGPCGGSTPEHCYVDKTRPCIWYKIYERSFKMGREEKLLEVLPPLDWEKVGTETW
GDVATCVKKNGTGKVLKSLVLDQGEKRYKTWDLIFRTVRQPDWWQGDDKYHAPAYTEPVS
DLERRFKAGEFVVACEIAPPLSMATKKLIENIELVKPFVTAINFTDNASATPRMTSWACS
RIAVEKGAEPVMQIAARDRTRASLQAEILGATALGVRNVLCVTGDSPVLAPKPRGRMDIN
DLDAIQMIWILRRMRDEGHYLDGRELKTPPKFFLGAAASPFASEPKFQALREQKKVNAGA
QFFQTNLVYDMDRFEVWLNEIAKRNILDKVYIMVGITPLKSAKMAHYMTQVPGVFVPDAL
LKRMDEAEKGGPPAMQEEGVKIALEIIEKIKKLKGQGIHGLHIMPVGWEDIVPRIVKEAG
LMKEALPA
>A0A7W6MNX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantimonas endophytica|TrEMBL
MSRTSPLSPSGINVSFEFFPPKSEKMEENLWRSIERLAPLGPRFVSVTYGAGGSTRERTH
STIERILKETSLTPAAHLTCVDASREDVDAVVRQYWETGVRHFVALRGDSQAGVGGEYVA
RPDGYRNAVELVAGLKAFADFEISVSAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNDVYERFVERVRKAGIYIPIVPGIAPIHDFTKIARFSSACGTKIPSWLAERFDGLEN
DEQTRSHVAAAVCAEQVLDLTSRGISDFHFYTMNRADLVYSICHILGLRAGTAGGETAEG
KAEAA
>A0A8H4XCP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sarcochroum|TrEMBL
MDKITDRIAALPGDGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGANFIQTQLFFDIQAYEHFENTLREHPSGAFKDIPIIPGLMPIQSYQMIKRT
TKLSHANIPDNLLERLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERTDLIPEPPANEEAVAVDDLPIPSLQINGSANMRSSSHSRSRQSRRHSSV
GSDPHNRVIVGDRPAVHPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGNPKTRQDINDLFVKHIQGQLSAIPWS
EEELLAESSTIQPHLLQLNSKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPTNEWNTLRAKLTSSELHDSVCFYASNARGDYVSSDSSDHVNGSTEDGAGPSPSTNAVT
WGVFPGKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNL
IHHDFVDKDALWKVLLS
>A0A0V0VQD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella sp. T9|TrEMBL
LLNLKAKVDAGADFIITQLFFNEMHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMKIVQ
LSKIVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRKLLNREHHVVPGLHFYTLNQEKS
ILEQIGFWKKAPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYLCRTRDWKQFPHSRWG
DVGNPAFGDLKHYLFSCIDQMDDSCALDMWDKELSTLEHVRDIFCNFIARTPNRHGHSVR
RLPWNENHLDPAADVLKNELIYYNSNGILTINCQAAVNGLPSSDPIFGWGEANGYIYQKG
YLEFFASSTCTTILLNHVQNFPSINYHAINFDGSFETFNYDEDATVALTWGVFVGQEIVQ
PTVANAASFRVWKVVAQLSFIQLFLFVFEQDEAFDLWQRWAGLYESGSIGRKLLQRIHDD
YRLITLIDNDYPQPCSLSALLRDVISDYIGGKNLTTDDDRLACRLALRASKHGITAEKEE
EEEAIIE
>A0A3A4PWR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MRIRDRLDQKVPAMSFEFFPPKDEMGFWDLYRTIESLRPLRPDYVTVTYGAGGSTRRKTI
ELVSRIKSDIGLETMAHMTCVGATRDEIQTVLDELNRRGIENVLALRGDPPEGTDKFEAV
EGGFRYASELVAFIKDRYRFCIGAACYPESHPESPSLRSDLDHLKRKVDAGTDFLISQLF
FGNEDFYVFCERAQRIGIRVPIIAGIMPILSVRQIKRFTQMCGAKIPPDLRRRIEAVEDD
PEAVRHIGMFHATRQCLDLIAHGVAGIHFYTLNRSTATRAIFQYLRTEQGGTAAP
>A0A1C5HMR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora coxensis|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTPEGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGDPGGEWVRHPEGVLYAEELVRLVRDSGDFSVGVAAFPYKHPRSPDIASDTAHFVR
KCRAGAEFAVTQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQMGTIERSVQLSGAPF
PPALAERFARVAHDPEAVRRLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWRSIQ
AGARV
>M7WXP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosporidium toruloides (strain NP11)|TrEMBL
MTTTPELRSSHPSTKVVDRIAQSDPSKPFYTFEVFPPKTDAGLVNLLDRIDRMSALNPAW
MHVTWGAGGSTQERSLQLAGESQSMGLETCLHLTCTNLEEGVLDRTLKRAKELGVVNLLA
LRGDPPRGEEYWTASSDKFQHATDLIKYIRKEYGDDFCIGVAGYPEGHADSADKLADVEY
LFEKQQAGADFVVTQLFYDVGVFMEWYRACRKRITIPIIPGIMPIQNYLSFRRMTNLCGT
HIPPQILDDLQRIQHDDAAVKEYGVQLAVKMMRELFENDIRGFHLCTLNLEKSVTRVLEL
LQWVEPGSTKISARLRKGLSPNGAPLPKVINSLRPAPSTGANVAGPDIARKDSPASWDEF
PNGRFGDARSPAYGEMDGYGVSLKLPPAEAMRQWGQPTALSDVSRVFSSYLRGSLPSNPW
SEEPLRAETEMISSHLIEMNDKRHWWTVGSQPAVDGAPSADSVHGFGPKGGYVYQKAFVE
FFLTSEELDELERKSDEDERRRRESGEGDDGLIKWFAGNARGEFRCNMGKGDVNAVTWGV
FGAKEIVTTTLIEEMSFRAWCEEAFALWNEWSLLYPANSPSRTFIRSLADSRWLVSVVHH
DYKEKDALWKWLLALKRPEEAQGAAKGEAEGR
>A0A1H8BDN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. CF402|TrEMBL
MDNPNFSIEFFPPKTAEGAEKLRVTRAKLSELKPKYFSVTFGAGGTTQRGTLDTVVEILN
AGEDAAPHLSCVGGTRESIREILTEFKSHNIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGDWFHIEVAAYPEVHPQAKSPQDDLLAFERKVKAGANSAITQYFYNADAYFQFVE
QTQKLGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLQGGAPGLHFYSMNQAAATTALWQRLV
>A0A2E9PS31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MTSDNGYKSGSNLERVLRTGHFAVTTELGPPKSADPDVIREKAAILKGFADAANITDNQA
AVVRMSSIGAGAITLQAGVEPVMQMTCRDRNRLAMQSDLLGAHALGLRNVLCLSGDHQVF
GNHPQAKNVHDLDSLQLVQMVTDFREKGCFQCGEEVEGDSPRFFVGAAANPFATPLEWRP
LRLGKKAKAGADFIQTQLVFDLPRFREFMKEVVDLGVHEQVYILAGVGPLKSPGMARYMR
DKVPGLNVPNEFVERMTAAGSGIEDKPTRSAAWREAGIAICVELIQQMREIPGVAGVHIM
AIEWEKAIPIITKQAGLLPRPSA
>A0A3B9A632|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
GADFILTQPIYEIQPALKFLERIKNEIEGFNTPLLVGVLPLVSARHAAFLQHEVPGVNIP
QEIHDRMTSAGERAAQTGIEIAFELIQQMAEIAQGIYLMPAFNRFDYAAEIIERVRKMEL
PTAQPKLSSLQG
>A0A009QP95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 625974|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHKELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A8H5Y8N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium globosum|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIHDIALLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A508YY55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus rhamnosus|TrEMBL
MKISQCFKDHQVISFEVFPPRKNATNIAMRPILNTLDAVKAADPDFVSVTFGASGNKPHM
GTLEVAKLIKDEFNLEPVAHLPAAQLTRAQVDAELRGFQEAGIDNILALRGDIPKSGRVS
EDFPYACNLIEHIHQVGDFDVVGACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYQFRERAALAGINVPIEAGIMPVINEHQIERMATMAGVHLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A7X3HF74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp. SW-Y-13|TrEMBL
MTDRYFSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSTRENIRAILQAYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFHIEVAAYPEYHPQARSPRHDLDNFVRKVKAGADSAITQYFFNADAYFRFVD
EARANGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKKLESFGDDKEAIRAFGLDV
VTALCERLLAAGVPGLHFYTLNTAAATKAIWQRLKL
>A0A8J6T4S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfacyla euxinica|TrEMBL
MQLKEKIAAKKFVVLGEFEPPKGADFSSFLKNVNLIRGRVDAFVVPEMANAVLKASSLGG
CAFLEREGIGAVLQVCCRDRNRLALQADILSAGALGVKNIMGVTGVDISYGDHPHARTVN
DLDLLELLDTINKLQDGKDLAGVDLRGTPQFCVGSTVDMGASGDLLKIELEDIDKKIDLG
VEYLVTNPVFDMRRLQQFVKRIDTEKVAVIPTVLLLKSAGMARYIDRNVKGISVPAEMIR
DIQKAPDKPKECIKIAGETINRLKDMGMAGVLISTVGWEDRLPQILDMAKL
>A0A3B9SGL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MNIKDYLENNILICDGAFGTFYSQFYGTEILPERAVLTHPERVLDIHGQYVSSGARLLRT
ATFAVNKESLNCDFDEIKKYIKNAFALAKKAAEGKNVFVAADIGPIMADKAEYTEISDAF
LEEGADIFVFETLPGIKELLPALEFIKSKNEKAFIICQVAVNSYGYTQTGESIKDIFEEA
KGNPYIDAIGTNCSIGPSHMYEVLSETELPENKYVCAFPNAGYPTLIQNRFVYNSNVNYF
CDKTEEIAALGVNIIGGCCGTNPGYISELDKREIKLSERKKTVVHKKEHFYESDKKQGLF
FDSKINKKIIAVELDPPKGTDYGELMATASYLKSEGVDAITFADSPSGRTRASSILMSVK
VKNETGAVVMPHICCRDTNAIGLSSQILGAYLNGIRNFLVITGDPVPGVSRDDVKSVFNF
DSVKLMRFIREMNETCFTEDNVFYGGAVSYSKKNTDSEIKRILLKKEAGATFFLTQPVYD
DKDIETLEYIKRKTGVKMLCGIMPLVSKRNANFIKNEITGITVPNSIVDLYDESMTKEEG
RAVGIKISADIMKKTYDFADGFYFTIPFNRTQTAKALLLEAKKLS
>A0A7W8QSL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis composta|TrEMBL
MFGSPTRTGPAFEAAPRPKRIGDLLKAGEPTFSFEFFPPKTPEGQQRLWKVIREIEALRP
SFVSVTYGAGGGTRDRTVEITERMATDTTLLPVAHMTAVNHSVRELRHLIGRFAAAGVSN
MLALRGDPPGDPLGEWVKHPEGLEYADELVRLIKESGDFSVGVAAFPYKHPRSADVDTDV
EYFVRKCRAGADYAITQMFFDADEYLRLRDRVAAKGCDVPIIPEIMPVVKTSTIERSEQL
SGAPFPRHLAAEFEKVADDPEAVRRLGLDQAHRMCERLLDEGAPGIHFITFNQSTATREI
YQRLAGGRRPLAAAARP
>A0A7U9RZ40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKISELLHSQDVGISCELFPPKLGSQLANAKEVVKEMAELSPSYMSITYGATGGTSEYTV
DMANEIQNVNHIPALAHLTCVSSTREKVHSVIRQLKEKQIENILALRGDVPVRADFPLPN
QYRYACELIADIKSQGDFCIGGACYPEGHPEAASMYEDLDHLKEKVDAGCDFLTTQMFFD
NNIYYNFMYKILQKNIHVPVVAGIMPVTNSGQIKKIISLSGNMIPPRFKAIVDRFWDNPA
AMRQAGIAYATEQIIDLIANGVNHVHIYTMNKPDVAGEILDHLSEIYIRR
>A0A7M1QDZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. MCCC 1A13316|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGKFAITSEIDPPDSADPAEVLKRAAIFDG
YVDAINATDGSGANCHMSSAGVCSLLTRVGYATIMQISCRDRNRIAIQGEILGGAAMGAC
NLLCLTGDGVQAGDHPQAKPVFDLDSMSLLQIARNMRDAHRFESGRRIETPPRIFLGAAE
NPFVPPLDWRPHRLAKKVAAGAQFIQTQYCFDIERLRDFMLKVNDLGLLEGPDRVFILPG
IGPLASARSARWIRENVPGVHIPDAVINRLEGAENQKEEGKRLCMDLLHAIREIPGVSGA
HIMAYRQEHSVAEIIETTGVLEGRVPWYPGRDDPKALNPESPGALPLT
>A0A512U5W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metschnikowia sp. JCM 33374|TrEMBL
MATVIERIKALKPDEKFCSFEFFPPKTDTGFRNLLARLHRMMALNPLFFTVTWGAGGSTS
EKSLDLAATCQKELGVTTVLHLTCTNTNKEVIDNALEKAKEAGVRNILALRGDPPRTQEY
WTPNCDFKNAIDLVRYIKEKYGDYFCIGVAGYPEGHVDGSDETQQNPRKDLPYLIEKVKA
GADFIITQLFFDVDKFVAYENLLQSVPELSNVVLIPGLMPITTHKVFVRATKLSHASVPQ
EISTRLEAPGNDDDMVKSIGIDILTKIISDVDRKTQGRVRGYHFYTLNLEKAVAFIIERS
PLLKLIDHNQSVDHEDAIGSDSESEEPAKVTTSRARKSLTVEDARIALVSDALSKDRKTI
IDISTGKGVLGKDATWDEFPNGRFGDSNSPAYGEIDGYGPNLKLHTPEKIIQTWGTPENT
KDISKLFMEYLSGKINVLPWVDSEISSETALIQEELFELNQRGWFTLASQPAVNACPSSD
KLLGWGPSNGYLFQKAFVEFFIPKQEWDTKLAPKLSQQIEDKTVTYFRGDSSGKITSNLR
IGEHHQNSKTAITWGVFPSKEVLQPTVIDYESFKAWNEEAFHLWVEWARCYKKDTKSYKI
LQSIYDDHYLISMTHHDFTEEYGLWTSLLND
>A0A0K1U6L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. CP1|TrEMBL
MTLVSERQAFNRPDEEAAARFRDLVRSASIEATPRQILTTEHLPDLLPAGTCVYVPFLPK
GQFSDTLEASRRLLDLGMQPVPHVPARMAQSRGQLRDWLAQLDESGVDRLLLIAGDSDAV
AGPFPDTLAVLESGLLAQFRFHGIGVAAHPDGHPMADRATLAQALSVKREYARTTATRLW
VVTQFTFDAEVVIDWLQGLGNILEEVPVYIGMAGPTRVKTLIAYAAMCGVGASARMLLRR
PGSARMLGAWKPDDMVRALVQYCLENPETLLRGIHLFPFGGLRQSAQWIRDHSGSCENNR
EAVP
>V7G5G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNJC394B00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDTIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A352SGV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MIKDLFHTNRPTYSLEVFPPKKDADVSVIYDALDEFKTLHPSFISVTYGAGGNTAENTFA
IASYIQNQCGIEALTHLTCAAIPDRLFLKNFLTNLYRNGIHNLLALRGDKPQWMSDEQFD
ARYYDHASDLVTDVKEMFDFSVAGACYPEVHQEAASLSEDIANLKIKVDKGVDFLITQLF
YDNETFFRFLDEARNAGITVPILPGLMPITSAGQVKNIIGMSGTKITKELADAIEKYKDN
PADLKKAGLDYSKRQMENLLAHGVDGIHLYSMNKVEIARAIYE
>A0A259CBA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 17-65-6|TrEMBL
MTSPIRASRETSRPPVRVSFEFFPPKTEEMERTLWASIDRLAPLGPSFVSVTYGAGGSTR
ERTHATVERIARETGLAPAAHLTCVAASRAEIDEVVRDYAQAGIRHIVALRGDPVTGVGT
AYEPHPQGYAHACDLVAGIRRLGDFEVSVSAYPEKHPESPSLDADIDYLKRKVDAGATRA
ITQFFFENDVYFRFLDKVRAAGIDIPILPGILPVTNFKQAANFAGRTGASVPAWLLKRFE
GLENDPETRKLIAAAVAAEQVTDLVDRGVGDIHFYTLNRADLVYAICHLLGLRPGAAETP
AQRLAG
>A0A3D5XTV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIRDILNKDTATISFEVFPPKKSTDFGNVEAAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGEIQKQHNVPTVAHLTCVCADRGSIGTALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKKNGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIVPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNLSEILKA
>A0A146HIR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycena chlorophos|TrEMBL
MIDEALQEAKQRGITNILALRGDPPRGEEEWTPIDPRFKNGTDLVKYIQSNPDYASHFCV
GVIYLVLSFGSCQSFFYLSAPHTMSAADGLDAALSRLETAVNSLPDSLHIGRRDSPLVAH
LTPPGTSERNTDADGFPTHDEGAYFAFNKPWERAFQNQAKPAVRNQLVSCGKYGTGIAFH
GNIMMDRSMPFL
>A0A6L9KW44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrovum sp|TrEMBL
MQSQQRYPKVFSFEFFPPKSLEGMEKLRHTRRQLAQLNPAFFSVTYGAGGTTRERTLETV
LEIRSEGHPAAPHLSCIGSTRESLSEVLKQYQVNGIRHLVALRGDLPSGTFGGGAFRYAN
ELVSFIREQTGDHFYIEVAAYPEVHPQARSTQENIQHFKRKVEAGANAAITQYFYNPDAY
LSFVDECEASGLDLPIVPGVMPIANFSQLSRFSEACGAEIPRWIRMKMQGYGDDTASIKA
FGLDVVTQLCDRLLSEGAPGLHFYTMNSAGLTSVIWDRLHLSER
>B4SJI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia (strain R551-3)|TrEMBL
MPAPGSQRAEAFINTFSLEVSAKAMPALRAEAGRIAPGTTISIPYLANEDDDARLAAART
VRELGFEPMPHLSARRIGSRAALERFLERAASEAGVAKCLLIAGDLSTPAGPYADSTSII
ETGLLERCGIKVVAMGGHPEGHPVMNTEDRWRVLERKCQVIEARGMAPLIITQFGFDADI
VLAWLDALRARGITVPVLVGVPGPASIARLARYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVSGLTAGHGQISPHFFPFGGIAPSLDWIERYRRRTSAASV
>A0A7Z8R2F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium HT2|TrEMBL
MTIKNKADLFSFEFYPPKTEQGDLNLEQVHRDLAKLNPDFFSVTFGAGGSTRDKTYDTVV
KIQKNGVSAAPHLSCVASTKENIREILANYREHGVSKIVALRGDLPSGMMSAGEFRFANE
LVDFIRVETGDHFQIHVAGYPEVHPQAGNATEDFNNFKRKVDAGADAVITQYFYNAEAYF
YFLDKCEKSGINIPIVPGIMPITNYAQLFRFSDMCGADIPRWMRKTLECFGDDKASIMAF
GEDVVSKLCQELLDNGAPGLHFYTMNQSKPTLAVWDNLSFA
>B7RNW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseobacter sp. (strain GAI101)|TrEMBL
MTSPAVSFEVFPPKSVDASFRLWDTAQALAPLAPRFFSVTYGAGGSTRDLTHDSAHVLRR
TSGLPVAAHLTCVGASKAETMDVANSFAEIGVTDIVALRGDPENGAKVFTPHPDGFADSV
ELIEALAATGKFTLRIGAYPEPHPESADQAQNIEWLKRKFDAGADEAITQFFFDADTFLR
FRDDCAAAGITKTITPGIMPITNWKSARGFASRCGTSVPTWLDDAFETAIRDDRHDLLST
ALCTEMCSKLVDEGVENLHFYTLNRPEMTRSVCRALGVTAQTSLADVA
>A0A6P5SAJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prunus avium|TrEMBL
MKVIEKIQEALLEEKKVLFSFEFFPPKTEDGVENLLERMERMVAHNPAFCDITWGAGGST
ADLTLDIANKMQNVICVESMMHLTCTNMPVDKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQIQGGFACALDLVTHIRAKYGDYFGVTVAGYPEAHPDAIGTDGLASPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDVFLKFVHDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPPEVTAALEPIKDNEEAVKSYGIHLGTEMCKKILAHGIRTLHLYTLNMEKSALAILMN
LGLIEETKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDLYPHGRWGDSRN
PSYGALTDYQFMRPRARDKKLVEEWVVPLRSVEDIHEKFKKFCLGKLRSSPWSELDGLQP
ETKIINELLGKINTKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKL
DALVEKCKALPSLTYMAVNKDGRWISNIGQTDVNAVTWGVFPAREIIQPTVVDPASFMVW
KDEAFEIWSRGWARLYPEDDSSRKLLEEVQNSYFLVSLVDNDYIQGDVFAVFADF
>A0A7T4EFD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium glucuronolyticum|TrEMBL
MKTTELFEKKTVFSLEIFPPKKTSSIKTIYDTLDGLEGTHPDFISVTFGAVGAGDNTHTF
PIASTIKKYYQIEGVAHLPAISLTRDQVLQRLHEMESYGIENVLALRGDLPVGGEAPSGH
FPHASDLIAFVKEHTDLNIIAACYPEKHPECPNRVDDIRNLKRKVDAGANHLISQLFFNN
AHFYDFLERCDLAGINVPIEAGIMPVVNKAQIERITSLCGADIPPKFRRMMDRFGDNPRA
MRDAGIAYAVDQIIDLITQGVDGIHLYTMNNPFIARRINDAVSNLISVTPARAAHRKVLA
FA
>A0A2M7N2F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium CG_4_10_14_3_um_filter_31_20|TrEMBL
MKVAEILQNTKKTLISFEILPPLKGDSIEGIYKTIEPLLEFKPPFLNVTYHREEVVYKKH
SNGLLERRIVRKRPGTVAISAALHYKYGIEVVPHIICGGFSREETENALLELHFLGIRNV
LIIRGDPDKSLREFVPEEGGNAHAIDLVKQVMNLNKGIYLDDELLNSTKTCFSVGVAGYP
EKHPEAPNMKSDLAYLKNKIDAGAEYIVTQMFFDNKKFFDFVAQCRKIGITVPIVPGIKS
VSVLSHINILPKTFYIEIPEALEREAKKCKTNDEIKQVGIEWAVAQSKELIAAGVPVIHY
YTMGKSDNTRKIVEAVF
>A0A4Q3M5I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKITQHIAEAKKTLFSFELLPPIKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKEQ
DNGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDNV
LALRGDARVADTSFIPTKGGHCYATDLIEHIKNHNDGKFLHEDVETFKSDFCIGVAGYPE
KHFEAPNLNADFKFLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKPI
STLSQLNVLPKIFHIDLPDQLVDALSHAKSNAEAKEIGTEAMIKQCKELIDFGAPVLHFY
TMGRPEQTKQIAKAIF
>A0A3N1V5Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 2132.2|TrEMBL
MLASGSPSYSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSVTYGAGGSTRGGTVKATQE
IAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRGDPPGDPMAPWVAHPEGV
HYAAELVRLLKESGDFCVGVAAFPDMHPRSEDWDTDIRHFVDKCRAGADYAITQMFFDPE
NYLRLRDSTQKAGCETPIIPEVMPVVGIKQLDRLPQLSNAVFPAAVKERMLAVKDDAAAV
RSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGLHQRA
>A0A1Z3M105|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas diminuta|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRSAVNVSFEFFPPKSDEAEANLWKAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIEGYKTIGVDH
IVALRGDPPGAAGIGGAYTPRADGYANATELTAALSRIGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTISLIPGVMPVSNFAGLKRMT
AACGAALPDWLAGHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAVA
>A0A1F9VBE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFCSPLOWO2_12_FULL_39_28|TrEMBL
MKIKEILKEKKTIFSCEFYPPKTSEGIQDLYKAVYDLKNLGPGYISVTYGAGGSTREKTV
EMVSKIKQEIGIEAMAHLTCVGHSKNEIKEVLNQIKDKGIENIIALRGDPPKGEKNFMPH
PDGFKNAHELTGFIHGSYDFCIAVAGYPEGHIEAPSKAKDWDYLEKKVHAGADFIVTQLF
FNNADFFNFEKEMRKRGVVVPIIPGIMPITNFHQIVKFTQMCGATIPEVLLKDLESVQDN
GGAVEEKGVEFATKQCEELILNGVKGIHFYTLNKSKATKKIIENLKEKHLI
>E6D6D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium acnes HL110PA4|TrEMBL
MAPDFISMTYGANGSRCDRTLRCTQHMVSTGLRTVGHLTCVANR
>C9S8T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136)|TrEMBL
MDKITDKIAALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
AFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPPRKAE
YQDAVDEESDDGEDFVWATDLVKYIRKNHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVEKTQAGADFIMTQLFFDIDAYDHFEQVLREHPSGAFKTIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDALMARLDAVKGDDEKVKEVGVDIVSELVDQIRAVKSKRTTGPQGFHFYTL
NLEKAVSFILERTNLIPDKEQEDEEAVIDDATTPPVVPTVQINGLHPGSHHRPGRRQSSI
GSDPHNRVIVSSASNHAYETNPEGAGLPAEPINTRANTLAISEGEGVLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVTQAVRLWGHPKSSVDISTLFIKHIRGELSAIPWSEE
GLSPETNIIQEQLIELNTRGWWTVASQPAVNGVPSRDATFGWGPSHGFVFQKAFVELFLP
AADWKVLSERLTGPEVEGTVCFYACNGNGDFATSDDSGGLVRTAVPASTNAVTWGVFPGK
EIITPTIIEEVSFRAWSEEAFKIWGEWSRVYGRGHESEKFLKTVKEEYWLVNIIHHDFVE
TNALWDLLRG
>A0A554XE24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidimonas taiwanensis|TrEMBL
MALSLSFEFFPPKTPEGAAKLRAARQRLYAARPDFCSVTYGAGGSTQEGTFATVAEILAE
GVSAAAHFSCIGATRERVRAQLAQLQAMGVKRLVALRGDLPSGYGLGGAFTYARDLVAFI
RAEFGDAFHIEVAAYPEMHPQARSPQADLQAFAEKVRAGADSAITQYFFNTDAYFRFVDD
AYALGVDVPIVPGIMPITNASQLLRFSDACGAEVPRWIRLRLQSYGDDVASIRAFGLDVV
TDLCDQLRTAGVPGLHFYTMNQADTTLAILQRLDLLPDVA
>A0A239LTM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tropicimonas sediminicola|TrEMBL
MPAPKVSFEFFPPRSVEASFRLHDTVQALAPLNPEFVSVTYGAGGTTRRLTHEAVSAIHH
TSDLRVAAHLTCVDATREETLEIARSYAEAGVRDIVALRGDPPKGAARFEPHPEGFRDTC
ELISALKQTGDFTIRVGAYPDRHPEAASDTADVEWLKRKIDAGADAAITQFFFEAETFFR
FRDACAKAGIDAPILPGILPIENWAAARRFALRCGATVPAWLDEAFETAVRDGREEILSI
AVATELCSNLLEGGVDHLHFYTLNKPHLTQDICRALGVTPELHLEDVA
>A0A520U3Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKITEHIKKANNKTLFSFEIIPPKKGNSIQQLYNCIDPLMEFKPHLIDVTTSREEFVYID
KGNGLLDRKTTRSRPGTLGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMAHQKYFQATEGGHPFAKDLVLQIKDLNSGKYLHNVMETDYKSDFCIGVAGY
PEKHLESPSLQTDLKHLKEKVDAGADYIVTQMFFDNQKYFQFVEAAKEAGIHVPIIPGIK
PIAVKRHLQLLPQVFSIDLPETLISAVESCKTNKDVRQVGVEWAIQQSKELLEANVPFLH
YYSMGKSDNIKKIASAIF
>A0A7S1UD38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeomonas parva|TrEMBL
YFSIGVAGHPEGHAESTSREEEIQHLKEKIEAGADFILTQFFYDVDVFIDYVEAVRGAGI
NVPVIPGILPIQNYNTFQRMTSICRTRVPPEVPRQLAPIRDDDEAVKRFGVAYAVDMARR
LMAANPGGLHFYTLNLERSVREIVSGLTAPTPTPTPPPGDEADGMPPAAPP
>A0A858BVU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminipila butyrica|TrEMBL
MKISDIFKKRQSFSFEVFPPKAEQSMEPLKKTLAELYKFQPDFISCTYGAGGTNKGRSSE
LCEIIEKDGQHAMTHFTCIGNTRQDIIEAIQEYRDLGVENVLALRGDIPHGLDGTNGDFS
NANQLLEFLRENFPDLCLGAACYPEKHMEADSLDTDIHYLKLKQEAGADFLMTQLCHDVE
AYERFLETIRAQGIHLPVVVGLMPALSKDSIIRMSLSNGCSIPRELAEIIGKYGDTPEDF
KKAGKEYTAKQILRYRQAAINGLHIYSLNKYADIVDILQAAGIDK
>A0A1D2R7M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon WOR_SM1_86-2|TrEMBL
MSQLRDNFGKKFIATGEASPPPGPDMTEYAHEVEEMKHLMDKIEGVNVVDLPGARVLMSS
LGASIYMLQKGVEPIFQMVVRDRNMAALQADLIAGAAFGIENILSLTGDHPACMASDHKG
AKPVYDLDSATLIKTMKMLNDGKMLNGQDMNGKTNFFIGAAIGPTSSPLDGEVYKTKRKL
DAGADFFQTQGIFDIEPMRDFLNLYDRLIGGDIASKTLVGIVPIRSYGMMQYLLTMPGVV
IKDKIVNSVKEASDEQKRTGRKGLIEDAGINLCIDLVDEIKGLGMKGVHIMPVGNVRALK
AIVDRL
>A0A1I4T7J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. OV329|TrEMBL
MDLPLSFEFFPTKTPEGAVKLRAVRQKLYGMKPEFCSVTYGAGGSTHEGTFGAVREILSE
GSDAACHFSCIGATRATVRTQLAELKAMGVKRLVALRGDLPSGYGAGGEFLYASDLVRFI
REETGSDFHIEVACYPEVHPQARSPEADMQAFATKVRAGADSAITQYFFSPEAYFRFVDE
AHAQQLDLPIVPGIMPITSSTQLMRFSDACGAEIPRWVRLRLQSFGDDTESIKAFGLDVV
AQLCERLIAAGVPALHFYTMNQAVATLGVLQRLGWKTPS
>E6MII5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoramibacter alactolyticus ATCC 23263|TrEMBL
MKNVRIKMKLKDQLRTDRPMLSFEVFPPKTDARLESVGQAVREIAALSPAYMSVTYGAGG
GTSQYTTTIAKKIAGLGVTPLAHLTCVSSDRRVVRARLAELKAAGIENILALRGDLPADY
VPGEYRYATQLIADIRAAGDFCIGAACYPEGHPENARQKDDIRHLKEKVDAGCDFLTTQM
FFDNALFYNFMYKIREAGIHVPVVAGIMPVTNAAQIARMVDLSGAFMPQPFLAMVDHFRD
DPASIYEAGIAYATQQIVDLFANGINHVHVYSMNKPDVARDIQNNLKAILGK
>A0A150V3M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidomyces richmondensis BFW|TrEMBL
MDKITDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQGLRPLFVNVTWGAGGST
SAKSLALAELTQRGLQLTTCLHLTCTNMSRKLIDEALEHAKVLGIRNILALRGDPPRSEE
YRDPNNPLAEQDDSNKDFCWAVDLVRYIRQKYGDYFCIGVAGYPEGHSDQSHPEHQSVKH
DLPYLVEKTTAGADFIMTQLFYDVKAYQNYEKTLREHDSGVFKTIPIIPGLMPIQSYQIL
RRTTKLSHASLPAELLRKLESVKGDDEAVKSVGVEILIEMIETLKGTESPYPRGFHFYTL
NLEKVITQILERTSLIPPVTPADFDGLENGLGEEAVMDEETHGHIPDEVKQKRRRRKSST
INSQPRNRLVVSRERASSTSSNRTSAYEAPEDEAGIPRDQINSRANTLAISEGEGALGRE
ATWDDYPNGRWGDVRSPAYGEIDGYGVSLHASVPDAKRLWGHPKTLGDISNCFRRHLEGK
IDAMPWSEEILQPETLTIKEHLLTLINKGWWTVASQPAVNGVRSTDPVFGWGPKNGFVFQ
KPFVEFFLPSSDWKRLRPKLEEDDQVTYFAGNATNDFASSDEQSVNPVTWGTFTGKEIIS
PTIIEAVSFKAWLEEAFGIWAEWQRVYPPGSESSKLLEQIRKDYWLVNVIHHRYVEEGAL
WRLLCDA
>A0A2T1KQZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter shengliensis|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRAEIGELLDLYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISDREKIAF
>A0A167CE73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beauveria brongniartii RCEF 3172|TrEMBL
MHIKDLLAETKRSGKPSFSFEYFPPKTAQGVQNLYDRVDRMYNFGPQFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGMEKVNDALRKAYKAGCTNILALRGDPPRAQEK
WTATEDGFQYACDLVRHIRATYGEHFDIGVAGYPEGCDDNDNEDELIEHLKYKVDLGGTF
IVTQMFYDVENFIRWVGKVRAAGITVPILPGIMPIATYASFLRRCKHTGCKIPQSWLDLL
EPVKNDDVAVREVGKKLVVDMCRKLMAADIHHMHFYTMNLAQATRMVLEELSWTPSAERP
LQQALPWKPSKGFGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRLKWGEPKSLRDIANTFVRYLNQEIDSLPWSEAPLTSEADSIKPALIE
LNQRGFLTINSQPAVDGVKSSHPVHGWGPANGYVYQKGYIELLVSPKIVDQVIQLVNTNP
SLTYYAVTKNGNLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFDAKSPSRVLVESVMDNWYLLNIVNNDFHDNTTIFELFKDLKVDGLETPIVVEAEAS
VAAEAEKPAAAQAEAVA
>A0A2P8CHJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prolixibacter denitrificans|TrEMBL
MNVSDIITQSDKTVFSFELLPPLKGQNADKLYRTIEDLLEFDPKYINITTHRDEMEYRTL
PNGLHERRTIRKRPGTVAIAASIQYKYGVPVVPHVVCGGFTKEETENMLIDLNFMGVKNV
LALRGDKLKSENIFKPEPEGHAYASDLVKQIVDLRHGKYLDPELKNNTPMDFCIGVAGYP
EKHAEATNPDVDLLNLKRKVEAGADYIVTQMFFDNQKYYDFVDKCRAAGITVPIIPGIKP
LSRKNQVSVLPGIFSIDIPEEFAKEVRKCKNNDEAREVGTEWAIHQAKDLIAHNAPCLHV
YTYGISDNTRQIAKAVF
>A0A679JJ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium bullatum|TrEMBL
MPTASHHRASRDGYRPIQVSIEFFPPKTDEMEKVLWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMIKETSLKPAAHLTCVDATREEIDEVVQSYWDAGVRHIVALRGDPQDGVG
TAYRPHPGGYARTSDLVAGIKRIGDFKVSVSAYPEKHPEAATLDADIDALKAKVDAGADQ
AITQFFFENDVYLRYVDKVRAAGIEIPIIPGILPVQNFKQSANFARRTGASVPYWLAARF
EGLDNDVDTRRLIAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKV
AAAKAA
>A0A223VJL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. NS1(2017)|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLIQYKSAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQAHSFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITTMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A8F9HAI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. TM-G17TGC|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8H3HBQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKLTDKLANHTSNLPYFTFEFFPPRTDQGYSNLLTRINGLAGLKPIAASVTWGAGGSTRD
RSLDLAGFCQADNGLDTILHLTCTNMEKGTIDEALTTAMERGISTVLALRGDPPRGEEYW
IPADPRFRHAEDLVTYIKQHPTFGNHFCIGVAGYPDGHSEGGSEEEQLAHLKRKVDAGAE
FIITQLFYDVEKFKSWLRKVRDTGITAPVIPGVMPLQTYATFLRMTDLCKATVPQHIQAN
LDAIKHDDQLVKEYGVSLAVSMIRSILVDGDIKGVHFCTLNLEKSVRKILDELGWTHDSV
HHNQIIIDASQSPHILPSSADAPHPVTFTISPSEATQHAATSLAEHTRTGTVRTAAEAID
SGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPPHVAISQWGRPTTEQDLSNLFLAYLND
KTSTTPFSPEPLSNESATILPHLVSLTKKGLWTVASQPAIDGALSSDSVVGWGPKDGRVF
QKSFVEFFATEADLEKVAKAIEDSGDGWVTFFAGNNDDGFLTNIPDSGSNAVTWGVFPGK
EIAQPTIIDRDSFLAWKDDAFMIWHDFGLCYPPDSPTRKLIEEVTKTRWLVSIVHHDYKD
SNALWDFLAKHLG
>A0A7V8H1W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CES|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSTERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSRQATPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPMWATRLGSQVLHKVEHAVKHPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTALLTERLIPCIELETRHRSSWPQWFQAQTP
RQLSPQPAPRTQPES
>A0A8H2ZWT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKFSEKLANHTSDVPYFTFEFFPPRTEQGYSNLLTRINGLASLKPIAASVTWGAGGSTRD
RSLDLAGFCQTDNGLDTILHLTCTNMEKGTIDDALTTAMDKGVSTVLALRGDPPRGEEYW
IPTDPRFQHAEDLVTYIKQHPKFGHHFCIGVAGYPDGHDEGGNEEEQLVHLKRKVDAGAE
FIITQLFYDVEKFKLWLRKVRNIGITVPVIPGMMPLQTYATFTRMTDLCNATVPQHIQAN
LDAIKHDDQLVKEYGASLAVSMIRSILVDGDVKGVHFCTLNLEKSVRKILDELGWTHGTL
HPNQIITDASQSPHILPAPADGPHPVTFTISPSEATQHAATSLAEHTRTGTLRTAAEAIN
SGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPPHVAISQWGRPTTEKELSDLFLAYLNN
KTATTPFSPTPLSEESNTILPYLVSLTSKGLWTVASQPAVDGALSSDPVVGWGPKDGRVF
QKSFVEFFATEDELVKIARAIEDSGDGWLTFFAGNNDDGFASNIPDSGSNAVTWGVFPGQ
EIAQPTIIDRDSFLAWKDDAFMIWHDFGLCYPPDSPTRKLLEGVIKTRWLVSIVHHDYKD
PSALWDFLAKHLN
>A0A417FSP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium AM31-12AC|TrEMBL
MKIIDKLNEDRIHISFEVFPPKTDAGFEKVKDATDKIAQLNPSYISVTYGAGGGTSKNTA
KIASHIKHELGVESLAHLTCASSTKEEVRQVIENLKQLEIENILALRGDIVPGMTFPSED
RFHYAYELVEEIKKHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITTAAQMKRSQELSGTVFPRRFLALLDRFGDYPD
AMKQAGIAYATDQIIDLLANGVKNIHVYSMNKPEVAAKIMENLSEVIKC
>A0A1F6V5G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Muproteobacteria bacterium RBG_16_60_9|TrEMBL
MRPNLSADAAQEILEREAIVRLMENASVEMTIHDEPHLTACGTLLRGSVNVYVSYLPKQN
WEQTQRTVMAVRAAGFEPIPHVPARQIEDHAQLEDLLRRFAAGVAVRRILLIAGDRRTPL
GPFGSTIDVLQTGLLANHGIQGIIVAGHPEGHPSIPAQALRANERAKVEAAQRAGLDVTF
LTQFCFTAAPIISWIQQLRANGIRSPVVAGLAGPARLATLVKYAAICGIGPSLRNLGARA
GALSQLATERGPETIIRALARAACDGTVDLAGVHFFSFGGLTRTCTWLSGAARGQIRLSA
DTFYVD
>A0A1J0DEX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter asymbioticus|TrEMBL
MELSVEFFPPKTPEGESKLHLVRERFSETLKPSFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
AETGDWFHIDVAAYPETHPQAKSPASDVDFFVQKIKAGANSAVTQYFYNSDAYFRFVDEA
YDLGVTQPIIAGIMPITNCTQLLRFSDTCGAEIPRWIRLRLQSYGDDIASIKAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLDLTK
>A0A0S8BIQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillales bacterium SG8_45|TrEMBL
MANNDRQYSCEFFPPRTEKGRESWREALTGLVSLKPAYFSCTYGAGGTTQEGTADTLKEI
LAAGFPAAAHITCIGSTEDKIRDLLGQYKEMGVNRLVALRGDLPEGMADPGVFRYAEKLI
AFIRKETGDAFHIEVAAYPEKHPQAASLQQDMENFRKKAAAGADSAITQYFFNTDAYFRF
VDSLQDMGVDIPIVPGIMPITNYKQIVRFSDACGAEIPRWILTRLEGYDDDLDSIRAFGL
DVVTAMCERLLDQGVPGLHFYTLNRAEPTATIWRNLGLT
>A0A3E4I587|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. D20|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPKELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A4W5K2U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hucho hucho|TrEMBL
MVNQVQRVEDTWRTCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIR
NYGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVN
RRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQW
ANLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEQP
NDEQSDKEQPGK
>A0A7Z9WCB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MSEYKSGSNLEKVLKAGHFAFTGECGPPKGANVEHLKEKLSYLKGNVDAVNITDNQTAVV
RMSSWAASTILIQEGLEPNFQMVCRDRNRLAIQSDILGVYAMGVRNMLCLSGDHQRFGNH
PQAKNVYDIDSMQLIALVKKMRDEGKFLNGEEIDVPPRLFIGAACNPFADPFEFRVYRLA
KKIEAGADFIQTQCIYNMDKFREFMKQVVDMGLHEKCYILAGVTPMKSVGMANYMAKMVP
GMDVPDSIIKRLKGAGKGKVAEEGIKIALEQIEEFKEMEGVAGVHLMAIEWEHKVPEIAE
RAGMLPRPQL
>A0A7C7QMD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MPLKEKIESGEHIVLGEFETPKGADFSRLLKNANQVKGRLDALVIPEMANSVMKASSLGG
CVFLQMNGFETVFQVCCRDRNRLALQGDVLAAAALGIPNIMAVSGEDIRYGDHPQAKAVY
DLDLIQLVETIQKLQRGRDMAGIELSSAPEFFIGSTINAGAVGSGLDTEIENLQKMIEAG
VEFVVTTPVFDLHQFQQFIKRIDTSQVAVIPTVLLLKSVGMARYIDRNIKNISIPSEMIR
GIQKAPDRLKHCIQIAGELINQLKDMGMAGVMISTVGWEDKLPQVLNAANL
>A0A6N4REP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter bilis|TrEMBL
MLDQLITKLKSNQAFLSVEVSPSLSSTIGQGVIDELESLKIADCFVCTDSPLARLKPSSI
LSSIKLQNALQKPLICTLSMRDRNSIALCGDILGANEFGLRAFLSLSGDGVKNGDCTGAK
GVFEESSLKLGRIIDGLNQGIAANGKVLKDSVDTIYNFSVINSYANNTESLKKKMLKKLS
NSLVQGLFTQPVFSLEAARFLLESMESINKELGQNCVMILGFFPVLSYKVALFLRDKLPG
VYIPDEWVQKLKKASIQGKEVEQKVGLELSNKLFKDLQTLHNKFHFMSANKPSLLREFVQ
D
>A0A829G5X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli KTE36|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A351B173|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MNSTTPSRLEKVLAAGHQAVTSEVGPPRNCDGSVIEHKAQMIKDYIDAINVTDNQTSVTR
LCSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAASFGICNILCLTGDHQYFGDHP
NAVNVFDLDSTQLLQTVRMMRDEGHLLGGHQFEPRPQMFIGAAANPFADPFEIRVPRLAK
KAAAGAQFIQTQCIYNMEKFKLWLKLARERGLTEKVAILAGITPMKNVGMARYMKNRVPG
IDVPDEIVKRIGGVPKEKQAEEGIKLAIEQIQELKEEEGVRGFHIMAIEWEEKVPEIVER
AGLYPRPQIN
>A0A1U8KB63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium hirsutum|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNELAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGVKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRVKEDVRPIFWSNRPKSYITRTIGWDQYPYGRWGDSRNPS
YGALTDHQFMRPRARDKKLQEEWASPLKSIDDIQEKFKSYCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGTTDVNAVTWGVFPAKEIVQPTVVDPASFMVWKD
EAFEIWSRAWAALYPEGDPSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>A0A1Y6H2Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas fragariae|TrEMBL
MTHLSFEFYPPKNDDQRAQLDRTSAKLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFDAAPHLSCVGGSRQEIRELLKLYRALGCRRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAVDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRTFGAEVV
ATLCERLITGGAPALHFYTLNLTKPTTQVLQLLGR
>A0A1Z8L8N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Owenweeksia sp. TMED14|TrEMBL
MKVIDHLKKSEGNTLFSFEILPPLKGTSIEGLFHSIESLMEFKPKFIDVTSHREEFVFKK
HDNGLLEKIHTRKRPGTVGICAAIQNKFKVDTVPHVICGGFTREETEYALIDLHYLGIDN
VLILRGDALKTDNQFIPETGGHKYAIDLLRQVSDLNKGTYLHDEVENTNPSNFCIGVAGY
PEKHFEAPSLNSDIKYLKSKVNAGAEYVVTQMFFDNKHYFNFVNKCRESGIHVPIIPGLK
PIASKKQLTTIPRNFYINLPDDLIRSIETAKTQSAVKEIGLEWCIEQSKELMRNKVPVLH
YYTMGKGESTEIIAKELF
>A0A1H1LIM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gramella echinicola|TrEMBL
MKVTEHIKKANGKTLFSFEIIPPTKGKNIQELYDNIDPLMEFEPPFIDVTTSREEYVYID
RDGLFDRKITRMRPGTVGICAAIKHKYNVDTIPHVLCGGFSKEETEYLLVDCHYLGIENV
MALRGDAMSHQKFFEPSNGGHHYACDLVKQIQNLNKGKYLHDVIEADDKADFCVGVAGYP
EKHVEAPSLNSDLKRLKEKVDVGADYVVTQMFFDNSKYFEFVKEARNAGIDVPIIPGIKP
IAISRHLQMLPQVFKIDIPEPLISAVEKCKNNKEVRQVGIEWCIQQSKELMEGGAPVLHY
YSMGKSSNIEQIAKAVF
>A0A2T0ULR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas songnenensis|TrEMBL
MSSQQHPLGISFEFFPPNTDAGRDKLMLVRDELAARNPRFFSVTYGAGGSTQARTRDTVR
TVSQSGVQTAPHLSCIGSEKAQLRDLLAQYREEGVKSLVALRGDMPSGMASIGELRYANE
LVEFVRHETGDHFDIAVAAYPESHPQAPNLDKDIENFARKMKAGANMAITQYFFTAEAYF
NFVDKARALGVDQPIIPGIMPITNYTKLSRFSDACGAEIPRWMRKQLEGYGDDSDAIAKF
GTEVVSHLCQRLLDGGAPGLHFYTLNQSAPVLKVVDNLVG
>A0A259RQD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halothiobacillus sp. 14-55-98|TrEMBL
MGSEAIMHTPLSCEFFPPKSDEGALKLRAVTEQLTLALKPEYFSVTYGAGGSTQDRSFAT
VQAIQTESGVPAAPHLSCIGSTRASIAAILDQYRALGIKRIVALRGDLPSGMRDPGDFRF
ASELVAFIRENSGDWFHIEVAAYPEFHPQSANARTDLLHFKQKVEAGADGAITQYFYSIE
AYARFLDDCEKLQVTIPIVPGIMPISNYTQLARFSDASGADLPRWLRKRLEAFGDDMDGL
RAFGHDVVTGLTADLVQAGAPELHFYTMNQAVPVINICRDAGLMPSQPN
>A0A399EP28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calidithermus roseus|TrEMBL
MKISALFQDSKPVFSFEFFPPRTPEGEQQLFQTIADLRSLKPGFVSITYGAGGSTRSRTV
EWVRRIRELGLEPMAHLTCAGSSREEIASLLDELTTCTDNILALRGDPPRGSKEFQPAPG
GFRYANELVAFVRERHGERFTLGGAGYPEGHPESVSLEADLQNLRRKVEAGLDFVITQLF
FNNALYFGFVERARKAGIGVPIVPGLMPITNLAQVRKFMDLCGASIPGPLLSRLESVADD
PQGVLEVGVEHATRQAAELLGAGAPGIHFYTLNKSPATRRVLENLR
>A0A2G6MZ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKTDSALEKILTAGYLAVTSECGPPRGADAEDIRKKAACLSGVVDAVNITDNQTAMVRMS
SFGASVIVKQEGLNPLLQMVTRDRNRLAMQADILGAYALGIDTMLCLSGDHTRFGDHPMA
ANVHDIDSIQLIQMVRTMRDEALFQGGAEIKKGAPKMFIGAAANPFADPFELRVMRLAKK
VAAGADFIQTQCIFNVPKFERWMAGVREMGLHKKCYIMAGITPIKSVGAARYMRNRVPGM
DVPAQLVERIGSVPKEEQAEEGIKVCIETIERLKNVEGVAGFHIMAIDWEEKVAEICERA
GLLPRPQI
>A0A0R3L1S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium jicamae|TrEMBL
MTVSDQLSPRLAALLPSASVEISSRGHQLAELRDHFAAGTDVTITFLPGDHYRHNVETAT
ALRRAGYNPVPHIAARELASREALDDFLARARGEAGVSRILLIAGDVAAAKGPFKSTRDI
CVSGLIEAHAVSSVSLAGHPEGHPFLELPDAMKVLGGWRDWGRQTKTRVDIVTQFCFEST
PILQWIGALDRAGIDLPVIIGLAAPATPATLTKFALRCGIGNSMRALRAQIGRFGRLLTD
TGPDDVVRGLRSAPPAATASIAGFHLFPFGGLRKAGAWLRDTEHGPLQHVERAAISHAGL
QNP
>A0A3B8RK90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lautropia sp|TrEMBL
MSMALSFEFFPPNTDAGLEKLRQVRLELAKLKPQFFSVTYGAGGATRDKTLALVETMTGE
SIEVAPHLSCMGQQRSQLAELLDHYSALGIRRIVALRGDLPSGMVQGGEFRFAEDLVDFI
RQRHGAQFHLEVAAYPEMHPQASSPDADLKAFIRKVRRGASSAITQYFYNADAYLRFRDT
VRAEGVDIDIVPGIMPITNYTQLMRFSESCGAEIPRWMRLKLASYGDDRESIRAFGREVL
VKMCERLLKESVPGLHFYTLNQDQASRAILDDLSLCS
>A0A0E4BNG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium diazoefficiens|TrEMBL
MTDLTKPATADGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYGAGGST
RERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPPGGIG
TPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDAGAT
RAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARAFVTRAGTSVPDWLAEK
FEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAKSAQ
KAA
>A0A0D2CHV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cladophialophora immunda|TrEMBL
MASEHDDRLPTLLSSLPASSYYFSLEFFPPKTSSGFSNLQARLARMATALRPLFVTVTWG
AGGSTATKSLELAEVCQRQVGLTTVLHLTCTNMKRSMIDEALEGAKEIGIRNILALRGDP
PREEYKDATSADDSESGSGGSGTESNQEFTWAADLVRYIRRKHGGYFAVGVAGYPEGHAD
ESHPEQGKQSVEHDLPYLAEKVAAGADFIMTQLTYDIEAYAAYEKRLRGYTDPDGKKLFE
KIPIIPGLMPIQSYQIIKRITKLSHAKLPEKISQRIERVKSDDEAVKRVGVDILSELVEE
MKTLPQPEALPRGFHFYTLNLEKSVSFILERTGLIPSISSEGSVEDKDGDSASDSDVVVV
DSKQDPPTIVTTGPVDSKNEKGQQPSGFIRRRRSSVNAQPHNRVITDGRAEPRTKSRRPD
SDTDPPGRGPSPNLKLTSQHLARDRGTGIPAASPTRRHSLLISEGQGSLGREATWDDFPN
GRWGPSHSPAFGEIDGYGPSLKVSPLMARKLWGYPRSREDVTELFRRHVLGELMAVPWSD
DIDPDLISAGGAASDDGPKNSSALRAETDVIRAELQSLISKQNYWTLASQPAVDGAPSSD
PIFGWGPPGEGFVFQKAFVEFFCGRDEWEEKLRPRLMKYGSDVLGWMKTDAEGVFESSEL
VARDQARKSKPSSTDTEKENTKPASPLQPADQKFSTSTSTASPSNTVNAVTWGVFPSREI
LTPTIIEAESFRAWAQEAYAIWNEWKRCFPRGSQEALFLEKMGRENVLVNVVGQAFRGGH
NGGKGEGARLWRILLAEEGDEKP
>A0A3A5IFN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. PK3_68|TrEMBL
MKLLDRLQNEVLTADGAMGTLLYSYGIDFCYEELNIEKPEIIEKIHREYIKAGADVIQTN
TYSANALKLARYGMEDRVRELNKAAVRIAKKAASSEERFVLGTIGGIRGIRKSSASLADI
EAAFQQQAEAILLEEPDGFLLETYYDFEELTTVLQLLRQLTDLPIISQVSMHEPGILQNG
LSLNQAFNQLESLGANIVGVNCRLGPYHTIQAFEEVTLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGQAAVHLRNEGVRLIGGCCGTTPKHIEAAKKALAGLAPITEKKVIARKPII
IKEPTPPVLPPLHEQVKKERTIIVELDTPKHLDTAAYIKGATALQQTGMAAITMADNSLA
SPRISNLAMGSLLKMQHHIRPLVHITCRDRNLIGLQSHLMGLHALGLHDVLAITGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGISFSGKPLKQKANFSVAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPIFTKEKIIEVYEATKHLSTPIFLGIMPLTSSRNAEFLHHEVPGI
KLSDETLARMKAYEHDKETAALEGVKIAKELIDTAAKLFNGIYIITPFMRYEMSIELIRY
IEELDRKMNERGITHVETISN
>A0A7K0G920|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enorma shizhengliae|TrEMBL
MHVDDIFTKAHAAGKIPVSFEMFPPKGELTLDKARDAAKKLSAYGPDFISVTCSAGGGGN
FAQTAAIASMLESEFNVSSVAHLTCISLTREGLKERIAQHKAAGVENVLALRGDRPTKDS
PLYGAPSDFSFAAQIIPALIEAGFCVGGAAYPEGHIECESLETSVEHLKLKQDAGASFFV
TQLFFDNEYCYRFLDLAEKAGITVPITCGIMPFVSKQQITRMVLMCGASLPSPVIKLLAK
YDDDPASLAQAGIDYACRQLQDLKEHGVDGLHVYTMNRPSVASAAMQALGR
>A0A150KBP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weizmannia coagulans|TrEMBL
MDFLETLKNRILVADGAMGTLLYAYGADTCYESFNLSHPEDIHAIHRAYIEAGASVIQTN
TYSANYIKLAQYGLEEKVKDINKAAVRIAKEAANRDTFILGTVGGIRGQRKTEATLAEIK
RTFREQIFHLLNEGVDALLLETYFDAEELYTVVDIAKKEADVPVIAQFSLIEPGVLQNGT
PVRDAFKELENRGADVTGLNCRLGPHHMIQAFEEIPIPKRAFLSAYPNASLLDYEEGRFT
FTNNADYFKTCAEKLVEQGVRLIGGCCGTTPAHIKATAEGVQGLLPVTEKTVRPPKIEIA
AAPAQYEPPLHEIVKKSRSVIVELDTPKTLNTARFFEGAKALHDAGIDALTMADNSLASP
RISNTAIAAILKEKHGIRPLVHITCRDRNLIGLQSHLMGLAALGIDQVLAVTGDPSKIGD
FPGATSVYDLSSMELIAMIKQFNDGISHSGKSLQRKTNFSVAAAFNPNVRNLDKTVGRLE
RKIRHGADYFITQPVFSTKKIEQIHEATKHLDAPIYLGIMSLTSYRNAVFLHNEVPGITL
TDDILQAMEKTNGDPVKAREESLAISRTLIDAALAYFNGIYLITPLERYELTVECTRYIH
EKTAVRSAGIF
>A0A5T1X7X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IQKQGEFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKPKAAIKIYEAVKHLLKEELRA
>A0A6N6V8A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. B2-b|TrEMBL
MSQFLNKLQNNVLVADGAIGTIFYSEGLDTCPEAYNLTHPEKVEDIHRSYIDAGADVIQT
NTYGANFEKLKAFGLEHKVKEIHKAAVQIAKKAANEDTFILGTVGGFRGVKQDDLSLSTI
QYHTEHQIDTLVDEGVDALLFETYYDLEELKGIVISTKRKHHIPIIAQLTASNTNYLVDG
TPINDALKQLVECGADIVGLNCHHGPHHMQRSFSHIELPDKAFLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIRYIKTSVENLRPVTHKNVIPINKKV
NRKKDINFKQSLTSKVKQGPTVIVELDTPKHLDTDQFFNNIGKLDDADIDAVTLADNSLA
TVRVSNIAAASIIKQRFNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEATKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEEVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITTHKEAIL
>A0A6C8A489|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSCVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHV
>A0A1R0LQ74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. IMTB 2501|TrEMBL
MVRHQASQPKLGEVIAAGDTSYSFEFFPPRNELAERRFWKALRRVEAVAPAFVSITYGAG
GTSRDQTVRIAERIAAETTLTPVAHLTAVGHSRAELRNIIGQYAESGITNVLALRGDPPG
DPGGEWIPHPQGFRHAAELVEMVRSCGEFSIGVAAFPEGHPRSADPDTELRHFVDKCRAG
ADYAITQMFFRVEACLRLRDRVAAAGCPTPIVPEIIPITDHKQLRRFAALSDAPLPAELA
ARLDRHRDDPAAVRRIGMEHAHAMCARLVAEGVPGLHFITLNRAEDALALHAAVAPRRPA
RHPVGA
>A0A2L1CLT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae|TrEMBL
MAMSQAIHLRDQSDVLDDFSVEVTTKDTTQLAAMSDAIPKGTIISIPFLSTESDADRIRA
AKMVRQAGYVPLPHIAARRLGSESMLSAMLSALVNDAQVSRLLLVAGDADPPKGPFLDTA
TILRSGILEQHGISNVSIAGHPEGHPVQNAAMLTSALLEKRLIMEAANIEWSIFTQFAFA
SEPVLAWIGELRRLGIEVPIHIGIPGPASVRTLLKFAAVCGVSASTSVLKKYGLSITQLL
SSAGPDALVNEYATGLSNAEYGDVRLHFYPFGGLHKTVDWLQEYRTRPS
>R5JPZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:189|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLCRDIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAALQNKYNITVVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESIFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDSDIYWLKKKVEAGAEYAVTQLFYDNQRYFEFVERVRKEGIDIPIIPGIKP
FKKASQLSMIPKTFKVDLPDDLVKETLKCKNDAEVQQVGVEWCIKQCRELMAHGVPSIHF
YSIGAVDSIKEVAKEIY
>A0A2E0XY57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHILDILERDPTTISFEFFPPRSDSAASELAGRMDSFRSLAPSFVSVTYGAGGSTRKRTH
DLVVSLKGNGGLDPVPHLTCVQQTPEELEDILSRYEAHGISNILVIRGDAPEGSDQYDSD
SEAFPHAVDLVRSIRRRNEIGTHPDKRGFGIGIAGFPEGHPETPNRLRQMDHLKAKVEAG
ADWITTQMFFDNRVFYDWCEQCDLNGISLPKIAGIMPITSLATMKRMADLAAGTNFPARL
QKRIYKHQDDPAAVEQIGVQWATEQCNDLLDHDVRGVHFYTLNRSDATMRIFSALGAHSS
IPLRNNPI
>A0A2L1D167|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae|TrEMBL
MVLKNEARGRNIRVSFEFFPPKSEEMEGQLWHAVSQLQDWDPDFVSVTYGAGGTTKAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPTFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGISRRETKSAGAAA
>A0A060XIG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
MVNLVQRVEDTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRHRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGGRAFLHGLG
>A0A847C9B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKIVDIYGKKKPELSFEIFPPKRDTALSDITETLDVLCELEPDYISVTFGAGGSSSNNKT
IKIARMIKEKYGVAPLVHLTCRCYSKEEIDGFVKELHENGIENVLALRGDENPDAPSKSD
FLHASDLTAYLRQNTDFCIGGACYPECHPES
>W7U2T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nannochloropsis gaditana|TrEMBL
MPSCTWPTSGWYFLLFITSNITLKYYAKQFESAFSLQALIQWVRNLSNCTDEIGLCRTSK
RISKRMGGRKIIDTIHSVLAEGGTTLSLEFFPAKTEEGMGNLLARIEDMVARLQPTFVTL
TWRSAFADESLWLKIGGIVQREFSVDVLLHLTCHLPRADLVRVLQNARDAGIRNILALRG
DPPIGEDRWQPVPGGFSNAVELVHLIRELHGDHFCIAVAGYPEVHTECWNSPDLPPSEQS
FAQDLTFLKDKVDAGADLVITQFFYDVPKYIRFHDKCREIGIPAHIPILPGYLPIQNYAS
FRKFTSWCKTSVPNPIDKALEKVKDDDEQVKALGVQEALRACRQLLDHGHRTLHFYTLNL
ESTVTSVVEGLGLLPKANLRELSWQRHKASGNRVRAKGGPAEEVRPIFWANRQTSYVSRT
NDWDEFPNGRWGDSRSPAYGELSHYYLEFKRPKVDRQKLWGIPTKHEDVYNVFVRFLDGK
VGSLPWCEQAPAPETSAISSNLKFLNANGYLTINSQPAVDGRPSTDPEVGWGGPGGIVYQ
KAYVEFFCSPDKLKVLMEEMDRHPNLSYHAVNVKGQEYTNTRSARVNAVTWGVFPGREIV
QPTVVDSVSFGAWKDEAFELWLTQWATAYQEGSLPRMLIHEIHDTFYLVNIVDENYGGDK
TAVAETEDAVRLEHKSEGNDVTRLEKTVNRHLDIFSLFKCVITRGFTSEQLFHFASETQR
ESEHLYAVVKELKAINHDTANENRMLRTSLMQTQQEIADIKSELKRLRIQRGLDLIKPTT
GFLHSGQHAAAGAITPLVASNTICKNA
>A0A8F6B845|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. HaHaR_3_91|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVD
KGNGLLDKRITRMRPGTVGICASIMHKYKVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VVALRGDARKDESYFKATQGGNAFASDLVQQISDLNKGKYLHDDIKVEHNYDFCVGVAGY
PEKHMESPSLNTDLKRLKQKVDAGADYVVTQMFFDNNKYFEFVKKAREIGITVPIIPGIK
PLAVKRHLQILPQVFKIDLPEDLIDAVEGCKDNKAVRQVGIEFAIQQSKELKEAGVPFLH
YYSMGKSDNIHAIASKLF
>A0A2U3UZ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tursiops truncatus|TrEMBL
MDRPKPKVLPAGHCCPSLGMRAWEAGSARFSVTPSISRSSAMVNEPRGHGGPSPRWEGSS
SGSESSKDSSRCSTPVLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKRLGLKNILALRGDPIGDQWEEEDGGFNYAVDLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEAGLKHLKEKVAAGADFIITQLFFEADTFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDDAIRNYGIEQALSLCRELLASGSVPGLHF
YTLNREVATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGDNITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWVEQWGKLYEEGSPSRTIIQHIHDNYFLVN
LVDNEFPLDSCLWQVVEDTFELLSGPPQSKRETEAP
>A0A353UGH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MSFKDILNSGKFVVTAEVGPPKGTDIKEMLHHMEILKGKVDAVNVTDNQSAVMRICSMAV
SRTAMEHGLEPIFQMTCRDRNRIGLQSDLLGASILGIKNVLCMTGDHVSAGDHKGAKPVY
DVESVQLLKIVDGLNNGKDMSGNELKGSTDFFQGAVVTPEANPIEPQLIKFEKKIRAGAK
FFQTQAIYDIEKFKDFMKHARKFPVKILAGFVVLKSAGMANFLNNNVPGIRVPQVLIDEL
KAAGKEKALDTGMNITARHIKQLKEEKICDGVHIMAIGMEDKVPEIMERAGLP
>A0A3D1BN54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MHAKRRRSKVSFRDLLNSGKFVVTAEIGPPKGTDIKEMLHHAEMLKGRIDAVNVTDNQSA
VMRICSLAVCKLMHEMGHEPILQMTCRDRNRIGLQSDLLGASVFGIRNVLCMTGDHPNAG
DHKQAKAVYDVESVQLLSIVNSLNSGRDMSGNELKGPTDFFQGAVVTPEANPLEPQLIKF
EKKVRAGARFFQTQAVYDIEKFKEFMKFAKKFPVKILAGIVLLKSVGMANYMNNFVPGIR
VLQALIDELKSAGKEKAIDTGMDISARHIRQIKEEKICDGVHIMAIGAEDKVPIIMERAG
LL
>J7LGI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis alba (strain ATCC BAA-2165 / BE74)|TrEMBL
MAPRGPAPRPRHIRDLLDSGEPLFSFEFFPPRNERSQERLWRAIREIEALGPSFVSVTYG
AGGGTRDLTVETTERIATDTTLMPVAHMTLVDHSVAELRHLIGRLADAGVSNMLAVRGDP
PGDPDGEWVSHPRGLTYAEELVRLLKESGDFCVGVAAFPYKHPRSADVEIDTDHFVRKCE
AGADYAITQMFFDAEDYLRLRDRVAARGCEVPIIPEVFPVVKLSSIPRSEKLSGAPFPRE
LAARFERFGDDAEAVRAFGIEHAQNMCERLLAEGAPGIHFITFNQSTATREIYREVAGHR
DGSAGAARP
>A0A1F9NVU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula sp. RIFOXYA12_FULL_46_16|TrEMBL
MMLRKKLTQGEFAVLVELNIPKGVDISELVTHVRHLKSRIDAVVIPDMDGGVMRMSALGG
GAVIRREGFEPVIHIYGRDRNRMAIQGDVLAAQALGIQNLIVVQGDAMANSDHPAAKTVD
DLNELDLLSMVQSLQKGVDLAGFDLKGKPAFFTGCQVQPIRDDKHLSEEYEKAKEKVAAG
AQFIVVPPVFDIPAYTQILNKLKSLKVPVIATVFMLKNVGMARYISINDPGSGLSDELIG
RIRKAKDREMECVHIAAEMIQSLKGVAQGVKISAVGWEDRLPAILDCAGL
>A9M4E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis serogroup C (strain 053442)|TrEMBL
METMLWDSIHRLQTLHPKFVSVTYGANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASP
DELRQIAKDYWDSGIRRIVALRGDEPPGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVH
PEAKSAQADLINLKRKIDAGANHVITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTN
FKQLGKMAQVTNVKIPSWLSQMYEGLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYT
LNRSELTYAICHILGVRP
>A0A4S8T7X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSIANS
APQNRVVIDKTSRSASSGSATFEAFDDEAGVPGEDAPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVE
FFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLL
EA
>A0A351F8J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKITEILNNGKMSLSFEVFPPKTDTAFESVHRATHEIAKLRPAYMSITYGAGGGTSRYTL
DIAEDIMNEYGVPTLAHLTCVSSSKETVHERIVEMNRRNIKNVLALRGDIPAEMMDEDRS
KWDHRYAVDLIREIKESGYDFCIGGACYPEIHPESPNQKEDIKHLKEKVDAGCEFLTTQM
FFDNNLLYNFLYKIREAGITVPIVAGIMPITNAKQVDRAIKLSGSFMPQRFKSLVDKFGS
DPLAMKQAGIAYATDQIIDLYANGIENVHVYSMNKPDVAEKIQSNLSDILGK
>A0A3G7YHB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. R5-89-07|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLAGYQPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLKNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A328AQX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium deserti|TrEMBL
MSPSDTALGPVARAGIGGTPRPNVSFEFSPPKTAEAEANLWEAIRRLAPLSPSFVSVTYG
AGGSTRDRTHRTVLRMLTETDLKPAAHLTCVEASREEVDEVIRDYWNAGVRHIVALRGDP
PGQIGGAYTPRADGYNNATELTRAIKAVGDFEVSVGLYPQVHPESSGIDHDIDVLKAKVD
AGATRAITQFFFDIDGFLRFMERVRKAGVAIPISPGIMPVTNFNALKKMAGPIGIEVPAW
LANLFEGLDKDPETRRLIAASIATEMCARLAEEGFGDFHFYTLNRAELTYAICRVLGVRE
TQPAPAEAAA
>A0A1Q3WQW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium 46-16|TrEMBL
MKVTEHIAEATEPIVSLEILPPTKGKSIESIYKQLDPLMEFKPAFINVTYHRAEQVYKKR
PDGSFERVEIRKRPGTVGICAALMNKYKIEAIPHLICGGFSREETENALIDLHFLGVKNV
LALRGDAAANEKFFTPHPNGHRYAEDLVKQVISLNKGSYIEEDIMDGVKTDFCIGVAGYP
EKHFEAPNLDTDIYYLKRKIELGADYVTTQMFFENQHYYNYINRCAEHGVTVPIMPGLKP
LTSKRQLTMIPSIFNVEVPVDLYNEMMKAKTDADCEQVGTEWLLAQCRDLLKNKVPVLHF
YTLGKPHVVYNVLKQLF
>A0A3D4T4I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKITEILNNGKMSLSFEVFPPKTDTAFESVHRATHEIAKLRPAYMSITYGAGGGTSRYTL
DIAEDIMNEYGVPTLAHLTCVSSSKETVHERIVEMNRRNIKNVLALRGDIPAEMMDEDRS
KWDHRYAVDLIREIKESGYDFCIGGACYPEIHPESLNQKEDIKHLKEKVDAGCEFLTTQM
FFDNNLLYNFLYKIREAGITVPIVAGIMPITNAKQVDRAIKLSGSFMPQRFKSLVDKFGS
DPLAMKQAGIAYATDQIIDLYANGIENVHVYSMNKPDVADKIQSNLSDILGK
>A0A349DET3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKITEILNNGKMSLSFEVFPPKTDTAFESVRHATQEIAKLRPAYMSITYGAGGGTSRYTL
DIAENIMNEYGVPTLAHLTAVSSSKETVHERIVEMNRRNIKNVLALRGDIPAEMMDEDRS
KWDHRYAVDLIREIKESGYDFCIGGACYPEIHPESLNQKEDIKHLKEKVDAGCEFLTTQM
FFDNNLLYNFLYKIREAGITVPIVAGIMPITNAKQVDRAIKLSGSFMPQRFKSLVDKFGS
DPLAMKQAGIAYATDQIIDLYANGIENVHVYSMNKPDVAEKIQSNLSDILGK
>A0A5N6UT46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus tamarii|TrEMBL
MFPFPLVGGPVKLRPKPFPPRWISPQSSFFNNHLSRNFAGTDSGNKMEKITDKIAALPPD
ANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGTTAQRSLELAEICQRQ
LQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNRDFT
FAVDLVRYIRQKYGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTQAGADFIMTQ
LTYDIEAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVKIPPQILSKL
EEIKHDDDSVKRIGVDIITNLVDGMRDIPCPALRGFHFYTLNLEKTVSFILERCDLIPPY
SEDFDAIEDGGDISAMDGAQLRSLTRRRASSINSLPHNRVIVDKLQASEVSSKASVSHEA
PATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLH
VPPSVAHRIWGFPVSREDISALFRRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELL
QLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLL
QKHGHEKLAWFAANGKGDFESSLPAQTSDADPIEMNPNNVNTVTWGVFRGKEIVTPTIIE
EVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNETKNDVWLVCVVGQDFGAGTEMGSEEE
EDEKKFMWRVLSNAK
>A0A348ZBX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKVSQIYKDKKKTLSFEIVPPEKNSELSSIDETLDILCELNPDFISVTFGTGGSENCNST
IEVARKIKEKYNIEPVVHLTCLNYSKAEIDLIAKQLQQSGVQNILALRGDKITNIQAKND
FKYASDLIKYMKSKYDFCFLGACYPECHPESENSVDDIKHLKEKVNSGAEVLLSQLFFDN
NYFYDFQEKCKVADIDVPIIAGIMPAISKSQLEKMVSLCGVTIPPQLERIVNKFGSNKDA
LFDAGMYYGISQIIDLLTSDVDGVHIYTMNNPMVAKRISSEIHNFIK
>A0A354A3L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MITESRLKNVLDSGNFAVTAECGPPKGADPEVVKSKGTILKGHVDSVNVTDNQTGVVRLS
SLAACALLRAEGLDPVLQMVTRDRNRIALQSDVLGASALGIRNILCLSGDHQSFGNQPQA
KGVFDIDSVQLIQTVRQMRDAGEIIGGEKLASPPELFIGAVANPFADPFKYRAARLATKV
DAGAEFIQTQCIFNLKRFKEWMGLVRDNRTADQVYILGGITPLKSARMAEYMAKNVAGMD
LPKDVINRMKAAPAKEQRQEGIRIAVETIHALREIKGVHGVHIMAIEWEDAVPQIVEEAK
LFPRPQA
>A0A1F8RHB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_64_43|TrEMBL
MSSANNGFRTESRLERVLRSGTFAVTAELGPPKNADPAVIRQKAGLLRGWADAVNITDNQ
TAIVRMSSIAAGKLAFDEGLEPIIQMTCRDRNRLAMQADILGAYALGLRNLLCLTGDHHS
FGNHPQAKNVHDLDSTQLIQMVVGLRDHAAFQSGEEIKGVAPRFFVGAAENPFADPADFR
PLRLGKKARAGADFVQTQLVYNVPRFREFMARVCDLGVDKQIYLLAGVGPLKSLGAAKYM
RDKVPGLDVPNEIVERMEAAGKGIDEKKAKAEAAKRVGIDICVELIQQMREIPGVAGVHI
MAIEWEEAVEEIVTRAGLAPRPNGSAAK
>A0A0Q7D602|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium sp. Root1277|TrEMBL
MSPHETALGPVARAAAGNTRRPSVSFEFSPPKTPEAEVSLWEAIRRLEPLNPSFVSVTYG
AGGSTRDRTHRTVVRMLKETTLKPAAHLTCVEASKAEVDEVVQAYWDAGIRHIVALRGDP
PGNIGGVYAPRADGYLNATELTAGIKAVAPFEVSVSLYPQIHPESPSIDHDIEVLKAKID
AGATRAITQFFYDIDAYLFFMDKLRKAGVTIPVSPGIMPVSNYKGLKKMAGPVGIPLPAW
LGNLFDGLDKDPETRKLIAASVASEMCVRLAEEGYSDFHFYTLNRADLVYAICRVLGVRE
APTEPSEVAA
>A0A2A7D8U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus anthracis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTEKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLEYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAALNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLKQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7S9VRK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. Cam5-1|TrEMBL
MTLSFPSVEETARAWQAPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFV
SVTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKAEIDAVADAYWEAGVRHIVA
LRGDPPEAGTKFQPHPEGYKGAAELVEGLRKRHPFEISVAAYPETHPDASCAQSDIDNLK
RKLDAGASRAITQFFFEPETFFRFRDTAAAAGITADIIPGIMPVSNFAAVQRMSAMCNTD
VPGWMGKLFEGLDDLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPATLEKTA
>A0A067BLC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprolegnia parasitica (strain CBS 223.65)|TrEMBL
MKIIDKIRAKLEKDETFYSFEYFPPKTQAGVTNLYSRIDCMAQMDPLFCDMTWGAGGSTD
KLTLEISANVQ
>A0A5R8N601|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea sp. KC401|TrEMBL
MAFELICEIEPPTKPDMKHVRHQIGTMSKVAHAFLIPDNHIGRATVSSVAVAHEVEAMGG
RGIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPASGNRTSDLTVRSMIEEAREF
SPGSRLGAAAGLRPLPAWKRAADFLFLQVSFSVEAQLRWREAHPVDAPVYAGVMVLASAG
HARSLATTIPDIALPDALVEQVTGDRQAGVEAACEQVLALRDSGAFDGVHLIPVSRYRDV
ERLLAPALG
>R8BQ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeoacremonium minimum (strain UCR-PA7)|TrEMBL
MDKITDKIAALPPDSNYFSLEFFPPKTSMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
AQKSLELAEICQRELGLTTCMHLTCTNMSRRLIDKALDDAKALGIRNILALRGDPPRRAE
YRDANDEPEPADEDEFVWAIDLVRYIRKQHGDYFCIGVAAYPEGHADESHPLGQSLEHDL
PYLVDKTQAGADFIMTQLFFDIKAYEHFETRLREHPSGAFKDITIIPGLMPIQNYQMIKR
TTKLSHANIPDSLMARLDDVKKDDEKVKSVGVDILSELVEQVKELKKGTPGPNGFHFYTL
NLEKAVSFILERTHLIPPDTPIEEEAVADELLPPIPSIQVNGTSPINSIKNISRRQSSIG
SDPRNRVIIAGGAPSHPEYEATALEASLPAEPVNTRANTLAISEGEGVLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSITQAMRLWGSPKSAEDINTIFIRHLRGELSAIPWSE
EEFNPETATIRDQLLGLNSKGWWTVASQPSVNGLRSTDSTYGWGPPNGFVFQKAFVEFFV
PSSEWKVLLEKLSRPEMKDRICFYASNAAGDFLSSDSSGGLDKEVKEASTNAVTWGVFPG
KEIITPTIIEEVSFRAWAEEAFGIWGEWAKVYGKGSESEKMLHKLQEDLWLVNIIHHDYV
EQDALWDTLLK
>A0A016EA08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis str. 1007-1-F #3|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEETPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMTAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A552PVH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis panniformis Mp_MB_F_20051200_S9|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>A0A1N6Y3U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter ulvicola|TrEMBL
MKVTDHITNAKGKTLFSFEIVPPVKGRNIQELYNNIDPLMEFNPPFIDVTTSREETIYIK
KEGLLDKKTTRMRPGTVGICASIQHKYNVDTVPHVICGGFTREETEYMLVDCHYLGIQNV
MALRGDARSEQKYFEATDGGHPFAIDLVKQIQKLNCGKYLHETIESEHCSDFCIGVAGYP
EKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVEAAKNIGITVPIIPGIKP
IAVKRHMQLLPQVFRIDLPQELIEAVDGCATNKDVRKVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAQALF
>H5WZT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora marina XMU15|TrEMBL
MRRVVDRLNSAGCPTFSVEFFPPRDEQDEAILWRSIRELEPLDPAYMSITYGAGGSSREG
TIRNIARVATDTTLVPMAHLTAVNHSVSQLRNVIGHFAAVGVHNILALRGDPPGDVMGEW
VAHPEGLNYAEELVRLIRELGDFCVGVSAFPYGHPRSADLETDTHYLVRKLRAGADFAIA
QLFFEAEDFLRLRDRVSAAGSDALMLPGIMPLTTPRTLHKTIELSGATPPRWLLERLEPL
SDDPKAFRAEGLNVITELCERLLAEGVPELHFYTFNRSKATRELVDRLGLRSPEPQLALA
GRP
>A0A024GX86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter siccitolerans|TrEMBL
MMFPVRIEVIPSQGIVGQVQALVPRTTTLSVTCLPHHGIERTLRTAVELGDAGYTVVPHL
AARSISSTAELTGIVRACGAAGISEVFVIGGDRKQPAGVYRSALPVLEDIAQYTGGTMRA
GVAGYPEGHPAVSPVDLLDGLLAKQHLAAHVVTQMCFSTEKIRDYAAFLRGEGVHLPVWA
GVAGAVPRTKLVALGTQIGVGSSLKFLSRKGPLARKLLSGDRYSPDSLIASLESQPGSIA
GIHLYSFNSLQSVPGNQLPAEPEQATTAALQTALIRGAARDS
>A0A2U2CJI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritimibacter sp. 55A14|TrEMBL
MTPNVSFEFFPPKTLDASFRLWDAVQTLAPLNPAFVSVTYGAGGTTRKLTHEAVEAIHGN
TGLNVAAHLTCVDATREETLEIARGYARLGVSDLVALRGDPPKGQGRFRAAPDGFASSVE
LIEGLKEAGDFTIRVGAYPDPHPDAADVDADVSWLKRKFEAGADYAITQFFFEAENFFRF
RDRAEKAGIDGARLIPGVLPVEDWAKASRFAAACGAHVPREIDTAFRRAVRDGREELMAI
AVCSELCADLVEGGAENLHFYTLNKPHLTREVCGALGISPKVELSQVA
>A0A2G2WBK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum baccatum|TrEMBL
MMLIYRHILILLQSSLENLVLRQFRVLQLFVVDEGEASVVAPNIFFVNQPILNEVVVGIG
TDAESEEGDNNEPLLSDYDSEELKLFRNKKSREVNDQLDMFLELKKVKKVKRLVLEKLEG
SYIDEFNKLEAYAKELGESNPGTDVIINISKEALDQGKTRTWDLKGIPCPHAIKAYIHDK
QDPEDHVNWWYSKEAYMLVYMYKIQPVRGSKFWKVDSAHAMEPPEIHKMASRPKLKRKKE
KTESRKGEWVWSASRKGLKMTCGHCGATGHNQRKCPLVIADTDGDESEEDEQLTIQPKRI
SEAKTRLKAKKVTHRPTGTRKIDFKGDENGVDAGADLIITQLFYDTDIFLKFVSDWRQIK
INCPIIPVKNPPSHTDILLCSLDGNSNLDGHRSPNETDRKRLRRPYQSKTFKVMISFAAK
FPIQAIANALCGQES
>A0A6A5RDU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Didymella exigua CBS 183.55|TrEMBL
MHISEKLARSRAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDITWGAGGRHS
KLTTEMVKVAQTVYGLETLMHLTCTDMERSKLDEALNDAYQAGCTNILALRGDPPREREK
WEATEGGFRYAKDLVKYIKDRYGNHFDIGVAAYSEGCDDNDDVDELIDHLKEKVDAGATF
VVTQMFYDTDIFLDWVEKVRAKGVDVPIVPGIMPIHTHAAFLRRATWTRCNVPKKWTEAL
EPIKNDDVQVREVGSELVAEMCRKLIDAGILHLHFYTMNLAQATRMVLEELELLPDVESP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGVGLKGTNEQNIKLWGTPTSIQDISNLFVRYMQGDLESLPWSEQAITEEANAIQQDLVD
LNRRGFLTINSQPAVNGAKSSDPTFGWGPRNGYVYQKSYLEVLVSPEYIAEVITRVERDP
EFTYYAVNKTGDLKTNAPSEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQDW
ANCHASTSPARYVIGDLIDNWYLLNIVHNDFHVTSGIFPLFNGLKVEGMDKKFESGTSAT
NGHAEANGTNGASNGENSGAQKDPKEQKDEQSLLETAKAAAVEFTNGIKNLSVSNSD
>A0A839WNV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas sp. RC10|TrEMBL
MIPVSFEFYPPKTDEQRQQLHRTAGKLAAHAPEYVSCTFGAGGSTLSHTPETVRRLKQDH
GLEAAPHLSCVGGSREEIRELLKLYRAIGCTRIVALRGDLPSGMGQPGDLRHASDLVAFI
RSEFGDRFRIEVGCYPEVHPQAEDARRDLAHFKAKIDAGADAAITQYFYNADAYFHFVDS
ARRAGVEVPIVPGIMPISNFSQLRRFSEACGAEIPRWMQRSMAAHGDDVAAIRALGADIV
TRLCERLIAGGAPALHFYTLNLAKPTQTILSRLA
>A0A7W9S3P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquamicrobium lusatiense|TrEMBL
MNQYRFSRRADLGDSIRVSFEFFPPKTDDMETRLWETVTRLQPLHPHFVSVTYGAGGSTR
ERTARTVARIIRETSLAPAAHLTCIDASREEVDAVIRQFVELGVTRFVALRGDPAAGAGT
GYRPHPDGYANGAEMVAALRRQGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDVYERYVERVRRAGIYIPIVPGILPVHNIGQVVNFSARAGAHVPLWLRERFA
GLENDPQTHALVAAAVAAEQVHDLVERGVSDFHFYTMNRSDLAFAVCHMIGIRPRNGNGA
SVAA
>A0A3E0GDE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 2221.1|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTNFVD
KCRAGADYAITQMFFQPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A543CC72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoallomurus bryophytorum|TrEMBL
MTAARPRTIREVLAAGKTTFSFEFFPPKTEQGARNLWQAIRRLEVLQPTFVSVTYGAGGG
NRDHTIDIVERIATDTTLTPVAHFTAVNHSIAELRQLIGRFAAAGVSDLLALRGDPPGDP
MGEWVRHPSGVEYAEDVVRLIKSSGDFSVGVAAFPYKHPRSPDIESDTRYFVRKCEAGAD
YAITQMFFRAEDYLTLRDRVAALGCDVPIIPGIMPVTQLSTIERSEQLSGAPFPRELAER
FEAVGDDPEAVRRLGIDQAVQLCRRLLAEGVPGIHFITFNKSTATSEVYSRLEISGSRRD
LLVP
>A0A1F1AXT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alloscardovia sp. HMSC034E08|TrEMBL
MHKPQFSLEVFPPKRNGPVGSIYDTLDGLQGVNPDFISVTYGTGKTADRTATARICHTVR
KEYNIPVVAHLTAQYLDHAQVDEALDMFQQAGVKAVLALRGDVVEGREPAGVFTYASDLV
RYIRQQCPDMPVYGACYPEVHPNSAGVVDELRHLKTKVDAGVSNLITQLFFDNDDFFRFV
EQARIAGIDVPIEAGIMPVTNAAQVRRMVTMCGARIPKELSAMLERWGDDADAMRQAGVL
YASQQIADLVSRGVDGVHLYTMNHPCTTRRIWANVSALFKEV
>A0A1A3FRU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. 1245801.1|TrEMBL
MPADSGCPKRMEFGPCGGVRPDGQCEMRPGPCVFDDVVPWSGHSPAPRPARTPRVLTDFS
ATPFDPDDIAATATVLAPGCDAVLVGEHQNKPDFPPTLMASLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSIDVETVLCVTGDGRGYDVRPDVSQAFDLDGPRLVSLAASVGIVAAVP
ETPTAPPVQRRPARLVEKQRAGASLAVLNHVPFPDMVADFMKSARAAGLAIPVIAAVAVF
TDTVSAAVLEGLPGLELDPTVTQRVLGASDPVEAGIAAAVDEARALLSIEGVEGVNVSGL
ASASGPRIGAEIKAEVGRRIREQGGGAP
>A0A246JZG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis witflariensis|TrEMBL
MTMNLNSLAEARRAAASPLFADLAGDIGASFEFFPPKTEKMEAQLWDTFRTLEPLAPRFV
SVTYGAGGSTRERTHATVARIAAESNVPPAAHLTCVEASRGEIDDVARAYWDAGVRHIVA
LRGDMPGGAPYQPHPDGYANAIELVAGLKKIAAFDISVAAYPEVHPDSDCVQSDLDNLKR
KMDAGANRAITQFFFAPESFLRFRDAAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTVI
PAWMVSLFDGLDDHPAARQLVSATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
MRPVQPAAEKAA
>A0A1M7SQR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanicella actignis|TrEMBL
MPADSAPAISFEFFPPATPEATLRLWRSVERLAPLGPEFVSVTYGAGGATRDRTMAAILT
IRDRARLNVAGHLTCVGASREQTLAVARAYAKLGVRRIVALRGDPPKGAARFEPHPDGFR
SAAELVAALRAAGDWKISVAAYPEVHPESPSLAADLDNLKRKIDAGADEAITQFFFDNED
YFRFVDAARKAGIEAPIVPGVLPIENFKRMSNFAARCKARVPDWMAKAYENADELGVTEL
LSAAICAEQCEELLAQGAPRLHFYTLNNPDLTFSVCRALGVQPTPMQIAAQGCG
>A0A101W9Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium BRH_c36|TrEMBL
MNVHPAASSDPGLALDRTAVQNTERPVPNTGMGRLESVLKSGRFAVTAELAPPDSADPQD
VFDRAAVFEGCVDAINATDGSGANVHMSSVAVSALLKARGQTPVMQISCRDRNRIAIQGD
ALGAAALGIENILCISGDGVQVGDHPGAKPVFDLGSISLLETLRKMRDEKQFLSGRPLTT
PPRLFLGAAANPFMTPRDFRVRRLKLKVDAGAQFIQTQYCFDVDILRSFMADVCSQRLDE
RAYILVGIGPLASAKSARWIRSHVPGVHVSEEIVNRMERAEKPAEEGRRICVELIQQIRE
IPGVAGVHIMAARQERHVADIVRKSGVRVDSRAQSET
>A0A1N6PW36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulosimicrobium aquatile|TrEMBL
MTSEASFAHRPGRPRPTVSFELMPPRRPDAAPKFWETARRLVATHPDFVSVTYGAAGTDR
ATARQVVGRLLQGTPVLPIAHLTCVGASREDVESVITDFLDEGVRSFLALRGDPPRDQPD
WQPAPDGVRSSTELVALLREVEASRCASDPAVALRGAARPLTIAVATFCDGNPAAGTTRT
QEVRRLWQKQQAGASFAITQLFYDASSYTDFVAEARAAGVTIPILAGLLPTTEPARLRRV
EELTGVRAPQRLLDALDALPDPEAQHAYGIAYSVDLAQRVLDAGTPGLHVYTFNKHRAAL
DLLEGVHLGGGSVGTGGGASAAAAPLVPDLASGPWVTGTSLPTTSAATHGAPV
>A0A503X7Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-3-4|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRMLKETSLTPAAHMTCVDAARHQVDAVIREFTDMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKGAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>R6G0W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium hallii CAG:12|TrEMBL
MNTMQTNPQDILKTLSLSFEVFPPKKWEDFPGLYETLDKLKGLHPEFISCTYGAGGSNSK
KTAEIASHIENELGIHSIAHLTCAALTEDKLLSTIENFKNAGIHSVLALRGDKPFDMSEE
DFANRQYKHPSEIIPILKKAGFRVAAACYPEKHYEAPSMEEDLHWLKHKVEQGADALISQ
LFFDNDAFYRFMDAADQKGITVPVHAGIMPITSAKMINTTINLSGASIPKALSDLIATYG
ENPSDMRKAGIEYAARQINDLAEQGMHYVHIYTMNHSETAKEICALIK
>A0A0P7IWT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria sp. 83E34|TrEMBL
MSLPKLSFEFFPTRTPEGRAKQVITRKQLSQYAPDFFSCTSGAGGSTREGTMQTIQDILS
EGIAAAPHLPCIGMQPQEVVDLLNEYKELGIRHIVALRGDIPSGMGAGMDGLFYANELVS
LIKNEFGDHFHIEVAAYPEFHPQARSAEDDLNNFVRKVKAGADSAITQYFYNTDAYFRFV
DDVQGRGVDIPIIPGIMPIASFSKLTRFSDTCGAEIPRWLRLKLQSYADDTAAIKSLALD
VVTEMCERLLREGAPGLHFYTLNQAGLVSTICQRLGY
>A0A1H6FFJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichales bacterium HS_08|TrEMBL
MKPDKLTLSCEFFPPRTEKGRDNLRQAYEQLKTLNPAFFSVTFGAGGSTQENTLDTVVEI
QQRGEYDAAPHLSCITSDKAMLRNLLQQYQQHGIQRIVALRGDRPSGFGSGAAGDLEYAS
ELVQFIREETGDHFHIEVAAYPEFHPQATSAQADLEFFRQKVAAGADSAITQYFYNPDAY
ARFLDNCAKMGIDIPIVPGIMPISNYQQLARFSDGCGAEIPRWLRWRLQDFGDDLASLQA
YGVEMVARLCQDLLDLGAPGLHFYTLNKADSVLNIAKQLNLR
>A0A4R5H1V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium M269|TrEMBL
MVSYAQGIDALNQSVSELRDISVSFEFFPPKTETMEQTLWKSVERLAPLNPSFMSVTYGA
NSGERDRTHDVVKRIQTETGVQTAPHLTCIDATKEELIAIAKDYWASGIRRIVALRGDLP
PGSDTPTSYASDLVALLKEVEDFDISVAAYPEVHPDAPNSQFDLLNLKRKCEAGADQAIT
QFFFDADTYLRFRDRSAAAGIDLDIVPGILPVTNYKTLVKFAGMTNVHVPNWLHKMYEGL
EDDDQVSRNLIGANIAMDLVKVLAKEGVRDFHFYTLNRCELSYAICHMLGVREHS
>A0A098TEC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea sp. BAL378|TrEMBL
MSQADANPHDPSAPLEPLPGHSSHGRLERILRRGEFAVTAELNPPDSANPHDVYERAAIF
DGWVDGINAVDASGANAHMSSVGICALLTRMGYAPIMQISCRDKNRIAIQGDVLGASAMG
VQNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRIMRDNSKFLSGRKLTSPPTVFLGA
AINPFAPPYDFRPFRLAKKIAAGAQFVQSQYCYDVPMFQKYMSQVRDMGLHKECFILCGV
GPLASARTAKWMRSNVPGVHIPDAIIKRLEGAEDQKKEGKQICIDIINEVKEIEGVAGIH
VMAYRQEEFVAEIVHESGVLKGRRPWRKEPNPADELVAARMEEILEQPRQLPHEMAGAVG
DSEAAG
>A0A3M7TY72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. KQ-3|TrEMBL
MNFNERIKEGLLVGDGAMGTLLYQEGYDGCFEKLNVTSPEKVRAIHQQYLEAGADVIQTN
TYAANSLKLSRYNLENRVDEINEQAVHIAKEAANDKAYVFGTIGGIGYIHPQEYDTEDIT
NSLEEQALVLLQSEVDGFLLETFYHFEELRSLVSFIRKRTDRPIVAQVTLGDIGVLQGGI
PLREALVQLEDEGVDVAGLNCRMGPYHMLRSLEEVPVLEKAALCAYPNASLPNVRDGKYF
YQSNPSYFGDMTEALIEQGVRLIGGCCGTTPDHVRQIRQAIDEKQLRPVTEKFVKGREAS
IVSVVSPSAEESLPDLSKKRKSIIVELDPPKALSQADEFMKGATALTEAGVDAVTLADNS
LASSRIDNLALGSLIKQKTKGNPLLHVACRDRNMIGLQSHLLGLHTLGINDVLAITGDPA
KVGDFPGATSVYDMASMDLIRLMKQLNEGISFSGKDLGAKTSFTVAAAFNANARHLDREV
KRLEKKIEAGADYFMSQPVYSIEQFKQVYEATKHLPVPVYIGIMPLVSSRNAEFLHHEVP
GITLSDEVRSHMAKFSSDPEASQKEGLRIAESLIDAATEYFSGIYLITPFLRYNMTVQLT
NHIKEKEALTLESLR
>A0A848YHB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altererythrobacter sp|TrEMBL
MSPTLDQMHEARTALDSPLFKGLPGDIDVSFEFFPPKTEKMGETLWQSVETLKPLGPRFA
SVTYGAGGSTRERTHEQVVRIQKEAGIPAAAHLTCVAATKEEVNEVARHYWESGIRHIVA
LRGDAPDGGGQYTPHPGGYANAVELIAGLKEVADFEISVAAYPEVHPDSPDAQSDLDNLK
AKFDAGATRAITQFFFNTRCFFEFRDKAAAAGINGEIVPGIMPVVSFAAVQRMSGLCGTD
IPHWMEGLFDGLDDRPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GMRPKGGA
>A0A8I1RJ19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altererythrobacter sp|TrEMBL
MSYAAIHPDWEKPRRNMVDGYSLEMTAKELDGLREAAPLIRPGTQVAVTFLPGEEMEQRV
QAAVLARELGFEPIVHLSARRIESEEQLDWYLGEITKRAQVTRVFIIAGDPPEPEGPYST
SLDIIETGLLEKHGITIVGVGGHPEGHPNNSAAELWDWMERKLAAVRARGMVPLVVTQFA
FDDDAIVAWVKEMRQRGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGISLTN
LIGSAGPDKLVDSLDKKLSDEEHGRVRLHFYPFGALKASAEWINTYDAKHQ
>A0A373ZP95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF15-31|TrEMBL
MKLKEYIQTKRIIADGAFGTYYISLYGDGSRAENGAGLSNLPELANIKAPERVIGIHTEY
IEAGAQFVRTNTFASNTKSLSADMEKVKENIRAAVMCAKMAAGKVDREIYLAGDIGPIPV
EGMLHSDRLTQEYIAIGETLLSQGIDILLFETFPELETILPAVTYLKENHDCTILVHFSV
NQFGYSNTGLSAKRLIAEANACPYIDGTGLNCGVGPGHMEKLIRKIAPDDTTFLSVFPNS
GYPKYLNNRLTFTDNAEYFTEKMKEIAALDVGIFGGCCGTTPEYIRRIAAGISADHPVRK
TETEAEKITVSEHPAYGFMERRVKEPAHKLIAVELVPPLNANDEKLLDAAHILKNAEVDV
VTFPDSPSGRTRADSVLMAEKIRLETGLCVMPHICCRDKNAIAIRSTILGASLNHITNFL
LLTGDPVPILFRQTTKSVFNFDSVGMMKIVQEMNSDTFTDHPVTYGGAINHNRMNTKAET
ERIRRKMAAGATFFMTQPIFSAEQADVIRKMKKETGATILVGLMPLVSRKNAVFMKNEMT
GIEIPDTVIERYREDMSREEGEACGAQITREFMAMTDDFADGYYFSFPFNRVHMLKKILK
>A0A8G0SSA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. S07E 245|TrEMBL
MSLLKTALHEHAFVCIMEFVPKPSAERFAALEAIMARKQLCGWPLTVSIGDRVGSPLDMS
PLDAFNSLATPVPALLHFSGKARERHDLLSQLQHMDAAGLDQLLILTGDRLPGHTPGQQP
VRYLESVAALQIARQARPDWLLGAALNPFKYREEEGAAQYLKAEKKLSAGADFLTLQLGY
DDQKHQEALQWMARQRTPKPLIACLMALTHGRAQMLEHVAGAVVTPSMRDVLAAELALSK
AYAQARSIQRLALQVVGLKLMGYAGVHLSGVHELAQLQTLERELEQVLASVRTLEQWAPA
WTASWQMPDLPAVTFTPPGANWRLDQSRVSASLREQVRYHLLSGMHGLLFGRENRASRAF
GWAVTRPLWSKPGAASLLHGLERGIKRPLVGCDTCGSCRLHDTLYICPESCPKGLANGPC
GGTSLNRCEFGDRECVHGVKYRVAKTVGETDVLRERLIPCVEVENRHRSSWPVWFQPAPV
VKVEPVVVVRRAAGSESVQREVAVAEVDN
>A0A846UV65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella sp. SG609|TrEMBL
MPAISFEFFPPKTDEQRDQLDRTARLLKGRGPDYVSVTFGAGGSTLSYTGETVARLHREH
GLDVAPHLSCMGGTRAEIAELLDGYRAAGYRRLVALRGDLPSGMASPGDFRYAAELVGFI
RQHSGEHFHIEVAAYPETHPQADDALADLRHFKSKVDAGANGAITQYFYNADAYFRFLDD
VRRLGVDVPVVPGIMPIGNFSQLKRFSDACGAEIPRWIAKRMQAHGDDAESIRELAADVV
AQLCQRLLDGGAPGLHFYTLNRAKATQAVLERLSI
>A0A235HJ12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum brasilense|TrEMBL
MTSGIPSVSFEFFPPKTEKMEQSLWQAIQRLAPLGPSFVSVTYGAGGSTRERTHNTVTRI
QKETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPETEGGVGGRYVPHPG
GYAYAADLVAGMRKVADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQFFFD
NDAYFRFLDRCAAAGITVPIVPGILPITNFARAVEFAGKCGAAMPKRFAETFEGLDSDPE
TRQLVAATMAAEQCQALQAQGIKDFHFYTLNRSDLTVAICRMLGVKAKQPAVS
>A0A223P5G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. meg3|TrEMBL
MTSHNFSIEFFPPKTPEGTEKLRVTRAKLAELQPKYFSVTFGAGGSTQQGTLDTVLEIMR
EGHVAAPHLSCIGSSRAALRDILNSYKSHGIKKLVALRGDLPSGFGAVDSASGEFHYANE
LVEFIRAETGDWFHIEVGAYPEMHPQAKSPQDDVQNFARKIKAGADAAITQYFYNADAYF
NFVDEVEKLGINAPIVPGIMPITNYTQLMRFSDMCGTEIPRWIRLKLASYGDDSESIRAF
GLDVVTQLCEQLLEGGAPGLHFYTLNQPAATMAIWQRLVA
>A0A1I7N7J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoflavifilum thermophilum|TrEMBL
MHVTEHIRKAQKTLISFEILPPLKGKSIESIYQHLDPLMEFNPAYINVTYHRSEFMFKKK
PDGSFEKVEIRKRPGTVGICAAIMNHYKVDAVPHLICGGFTKEETENALIDLNFLGIDNV
LLLRGDPPKNEAYFEPEPGGHRYAVELIEQVVNMNHGIYLEEDLIDGVKTNFCIGVAGYP
EKHYEAPNLETDLYYLKQKIDKGAHYVVTQMFFDNQKYYDFVKRCREKGIDVPIIPGLKP
ITSRKQLSMLPRVFHVDIPAELCTEIMKCKNDKEVEEVGKEWLVYQSRELIKFGVPVLHY
YTLGKPEVIKKALAEIL
>A0A3B8KXM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
KRLEAVQDDREAELAVGVDYAIEQCRELISEGVPGIHFYALNRSQACARILDALGHGASP
ELSGEH
>A0A496BPV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. AF19-14|TrEMBL
MKVIDLIRNSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIVHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A3D0NEJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MASVAQFYTSEHKGLSFELFPPKTDQGDAALMRHMEVLMQFSPDYITCTYGAGGSTQTKT
MDVITAVKTAFDVPVASHLTCVGSTADDLRSYLEEASRKEVDFLVALRGDPPQGDSKFQA
VEGGFSYANELVEFIRAEFPQFGMAVAGYPEVHQEALSAESDLENLKRKVDAGADIVITQ
LFYDNTDYFDFCDRCETAGIEVPIVPGILPVTNLAQIQRITSLCGSKLPDQFVQRLSQKE
DDADWQFEVGVEFAAAQVKELIDQGAAGVHFYVLNKSQATLRVLEAVDW
>F2BXR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dialister micraerophilus DSM 19965|TrEMBL
MSLREIFNRKQVFSYEVFPPRKNAGIDSVCETIKELKKLNPDFISVTYGAIGARNNTDTF
KIASLIKSYGIESITHLPCLELKKEEVLLKLEELRKLGINNILALRGDKPEDGYRKGDFK
YASDLITFIKEHGDFNIIAACYPEKHSDSKNIVEDVKSLKIKVDAGANQLITQLFLDNDY
FYAFKERCELADINVPIEAGIMPVVNKRQIEKMTSFCKVETPKKFLKMMNRYEHNKIAMR
DAGIAYAIDQIVDLITQGVDGIHLYTMNNPYVAKRIHEAINNLLLDKTEFLKEA
>A0A2D7NK92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MHFKDVYQTKDTTFSFEFFPPKTGNGWTVLEEAISKLVPLNPDFVSVTYGAGGSTRDRTH
ELVLKLQENQMLDPIPHLTCVEHTKQEIQQILERYAQAGVSNILALRGDVPVDSSVKNPF
EHFAHAADLVGTIKEFNHSGIHADSRGFGISVAGFPEGHPETPNTLTQMDHLKAKVDMGA
DVIFTQLFFDNNAFFDWRERCTLAGIDVPIVAGIMPIVSMQGLNRMADLAAGTRFPASLL
RALERGQDDPESVRRIGTHWATEQCLDLLDKGVSGIHFYTLNKSEATLEIFKTLGMKSV
>A0A1C2HB02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioclava sp. SK-1|TrEMBL
MSTPNISFEFFPPQSLEASFRLWETVRVLAPLQPKFVSVTYGAGGTTRKLTHEAVTTIGK
NYGVNVAAHLTCVNASKEETMEIVNSYAEAGVTELVALRGDPPKGQENFTAHKDGFQTSI
DLIEALAKDGRFNIRCGAYPEPHPESADTLADVRWLKRKVEAGATSAITQFFFEADTFFR
FRDLCEKEGVNAKIIPGILPIQSWKGTKRFAQSCGTKIPAHLEEAFEAAVRDDREQLLAT
ALCTELCDTLIQGGVEDLQFYTLNRPNMTRDVCHALGITPRASLEDVA
>A0A1M6KJA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malonomonas rubra DSM 5091|TrEMBL
MTEISIELVPRSEKSLREELQLVKDKFPSVNRINIPDILRFKMRSWEGCAIAGESFSNTI
PHLRAIDFDPNQPLQIVEELCADAIEAVLVVTGDPPQDMSHKCYRTSCLEMIRRLKREVP
QLTIYAGMDPYRNGIKEEIDYIKAKQDAGAEAFFTQPFFDLRLMEIYQGFMQDCTVYWGI
SPVLTENSQNYWENKNNAVFPPDFEATLNWNREFAQKALSFAEAHQDNIYFMPIRTDIAA
YLDGIL
>A0A2E7CW84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MQTSSESTLRRTTWKAVRLLKQFDPDLGIGVAGYPEKHQEAIDAQTNLENLKRKVDAGAD
AVFTQLFFENDNFFRFRERYYQIGIKVPLVAGIMPITDFSRIQRITQLCGAYFPADLHRR
FEAVQDDKEAQFEIGVEHAIAQCRQLFDQGVAGIHFYILNQSAASERILEGLNLRVEQDQ
QQRELALA
>A0A2A6E821|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella forsythia|TrEMBL
METVIDLIKNSQRTAFSFEILPPLKGNSIQSVYQVIDKLREFEPKYINITSHHSEVIQRV
EPDGSIRTVNLRKRPGSVAIASAIQNKYGITAVPHLVCKGFTKDETEYGLIDLNFLGVNN
LLLLRGDIKRLDLTKDPKRCHDHATDLQHQVNDFNRGIALDGSAIEDIETPFSYGMACYP
EIHEEAPSMESDIRYAKMKVENGAEYLVTQMFFDNDRYDAFVARMRAEGVTVPIIPGIKP
IVFKDQLTVIPKIFHCTFPEPLTQALRQCKNDDEAKAVGIEWCIAQCRDLMKRGVPSIHF
YSFLASDSVRQVAKIIY
>A0A0Q5Z5X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramlibacter sp. Leaf400|TrEMBL
MKKDKLPISLEFFPPKTEEGAVKLRAARQKLYALKPEFCSVTFGAGGSTQEGTLAAVKEI
MAEGCPAAPHLSCIGQSHETIRERLAAYAAAGVQRIVALRGDLPSGYGLGGEFRYASDLV
AFIRSETGRQFQLEVAAYPEVHPQSRSADSDLAAFIAKVEAGADSGITQYFFNADAYLRY
VDELRGRGVQVPVVPGIMPITSSTQLLRFSDACGAEIPRWIRLRLQGFGDDTESIKAFGL
DVVTGLCERLRAEGVPGLHFYTMNQAAATLEIARRLGL
>A0A0B1T0L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oesophagostomum dentatum|TrEMBL
MLVFEKFVRDCREIGITVPIIPGIMPIMGYDSIRRIATLSQLTIPESILLDLEPIKHDDD
AVRKYGTVKAIEMCRRILSNGSAQSIHLYTMNREGACRLFCQMTIESLDCFVFDTLMLMI
HLASFSYPHFRCKEDVRPIFWSARPKSYIYRTSDWDDFPNGRWGNSSSPAFGDLQDYYLF
HLKGQMKKEVLLKMYGEELASFDDVKKVFVNFISQSENENGVKVTTLPWTEQDAGVQPET
KLINEQLLWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFISKENAVS
LLEIIDDYYPRINYHILNHDGSFDRMNGESTTPIAVTWGVFPGTEIAQPTVVDPLAFRAW
KDEAYETWIKNWANLYPKDSISRNVIQKIHDDFCLMNVVDNDFQKPVIIYEILEKMLKRT
EERKAASA
>A0A3C0ACS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MRISELYQDGTFGLSVEIFPPRNESGDAELFKTLEELVRYQPAFVSCTYGAGGSTSKRTI
ELCALIQDQLDNTATAHFTCVNSTREELVEWLHNAVDAGITNIMALRGDPPAGQETFVPA
DGGLKYANELVSLIRQHFPDMGIGVAGYPECHPEASDSAFDLTNLKRKVDAGADAIYTQL
FFNNEHFYQFRERCQQAGINRPIIPGIMPITEYRRIQRIMSMCSSEFPADLVGQLEAVQD
DLDAQFEIGVNYAIRQCEQLMEVGVPGIHFYVLNRSQACKRIFDALGFPETQDKIAT
>F3AI61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 9_1_43BFAA|TrEMBL
MKIIDKLQENKIHISFEIFPPKTDAGIEAVLSATEQIAKLAPAFISVTYGAGGGTSKNTV
QIASDIQKKMGVTSLAHLTCASSTKEEVLSVVDRLRAEGIENILALRGDIPEGREFPETD
QYHYAYELIREIKKQGDFCIGAACYPEGHVENEHKEDDIAYLKQKVDCGVDFLTTQMFFD
NAILYNFLYRIREKGITVPVLPGIMPVTNSRQMTRICKLSGTVLPQRFHAILDRFGEKPE
AMKQAGIAYATDQIIDLIANGIDHIHIYSMNKPEVAAAIMTNLSEILR
>A0A2V7ATP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MERRRYQNLLRERLGSGQFVASIEFVTPEASDELEGAIAPLIDLAEHIKADSRFHTIAIT
DRVKSDHDHDPVLVGARVAEACGKMPTVHLSGKDRDAAWTADALRRLEASGLDDLLVVTG
DKVKVEPGGRQVRYYDSVNMVAQARAAGAFHIAAAVSPFKYREEDLMNQYLKMAKKEKAG
ADCFITQVGWDMLKLKELMTYRRRRGFAAPVMGGVMLLTVARARYIRQNKLAGITITDAL
QARLEEEAKQPDKGVGAAYRRLALQIVGLRRLGFAGFQLTGMHQFEKLDKLFRQIDGLER
GLTHEGAWWDAWWLALRGHERAPVVTAPRPYYLFKELAEPGGWSLPSDRLTLRDLDPPAS
PNAELERYRSLDRLDSMIFKDGSPGAALLKPIARLVPSGGALDRGLLWLERHVKEPVLGC
QTCGFCRLPYTSYVCPETCPKGLANGPCGGTSENTCEFGDRECIHDRKYRIARDAGRLAE
LEDVLIPDVDATTRGTCSWTNHFRGADPAVVRLSEIRAKGSRA
>A0A7V2MV56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MANPFREALAAGRFCYVVELVASRLRREAQVLEVAAGLARIPEVVAGSVTSYAGGAMGHD
PIRVAAAARARGLTPNVHLTCVAQDRDGLRKTLDDLAALGIENVFALTGDYPRAAAAPGA
GAEPGSAPVFDLDAVQLVRLIDELRRAGRRFHVAVAVSPFKYTEADCVWQYLKLEKKVAA
GADVAITQVGFDARKFAELKRYVDARGLGIPLLGNVYVLGPRAAAKMARGEPPGCWVPPA
LLETVQRESAAPDGGLRARLERAAAMVAVLRGLGYAGAYLGGTHEPAHIAWIIRRAEALA
PAWPALAAQLAYAPVHGFYLDDPAALPWEPAPRRAASRPSPAAGRARAPARGRPLLPRLL
DALGRALPVGREQPLGRLLGRAFAWADRHRPVAAAVERLELAIKRPLFGCQACGNCVLGV
LEYVCPQTCPKQMRNGPCGGATDGRCEVVDRPCIWGAVYERARAAGRLGALLTYVPPPDR
TLRGTSSWINYYLGRDSRP
>A0A2V7C4H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MSNPLREALATGRFCYVVELVASALTREARLLEAASGLARIPAVVAGSVTSYAGGAMGHD
PLRVAAAARARGLTPNIHVTCVSQDRSGLEKTLDDMHALSLENVFALTGDYPSAGDQPPV
FDLDSVQLVRLIDERRRGGMAFHIAVAVSPFKYTEADCVYQYIKLEKKIADGADVAITQV
GWDARKFEELKRYLDERGLRTPLLGNVYVLGPKTAERMATGRPPGCWVSPELLAAVRAES
LAKDGGRLARLERAARTVAVLRGLGYAGAYIGGTHDAAHLAWIIRRADELAPGWEALTAE
LRYGAAGGFYLATSRESLRSGARAAPPRLWADLLPRLLDRFGRVFSVTHDTRLRRALARV
FAWIDHRRPAAALLERAELAIKKPLFGCQACGNCVLGHLEYVCPQTCPKQLRNGPCGGTN
YPGRCEVVPDKPCIWVTVYDRARASGRLDALKTYVPPPDRRLRDTSSWINYFLDRDSRPD
PKRA
>A0A0K2ZD83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas translucens pv. poae|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKTYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQASDALSDLRHFKAKVEAGADGAITQYFYNADAYFHFVDA
VRKLGVQVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQALGDDGDAIREFGADLV
AALCQRLLAGGAPALHFYTLNLAKPTTSVLSRLE
>A0A286FFZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma fluviale|TrEMBL
MFLEKIKSAASGVMLYGITPPKASTQPERVAEIAQKTVERLTNLDIDALVVYDVQDESAR
TTEERPFPFITALDPLVFASGYLEALTIPKIIYRPAGKFSVQELSDWLEKLHEHTFYPVF
VGVPAPDFPVKTSLQEAYKIWSKHQDTSVIGAVTIPERHNALNDEDVRMLDKMNCGVSYF
ISQCVFNLDYAKQLIEDLYLRCNRQQISPPTIIFTITACGSVKTLHFMEWLGIHVPDELK
EELKTSEDILEKSVRLCLEIAEALTTYCIERSIPFGFNIESVAIRKAEIEASIDLAHRIS
QMLTDKGVRKPSKESEVTFID
>A0A1E5KS42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus rivorum|TrEMBL
MKIENYYSQKKPVVSLEFFPPKKEAAIETIYQALEEMKEVQPDFISITYGAAGSKTDNKT
LELASMIKNKYGIEPLHHLSCVANTKEEISQLLAQIKGEGVENILALRGDIPLDPKNCPN
DFVYAKDLITSIKETNDFSVGAACYPEGHIDELTSRENIDHLKAKVDAGADFFVSQLFFD
NDTFYRLVEDARNGQVFAPISAGIMPILSRGQVEKMIFMCGTSLPSELIKIIHKYEHSIE
DLRKAGLEYALKQIDDLMNHGVDGIHVYAMNRPVVAKEAMSLLRGS
>A0A2I0H095|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. 4Bb|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALSV
RGTTEIAPHMSCIGDDKSEIAELLEYYKTLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
YIREHSGDHFHIEVASYPEMHPQARSFEFDIDNLVNKYQAGANASITQFFYNADSYLYLR
DKLEKRGIDTVAQPLVAGIMPITNSSNLLRFADSCGADIPRYVRKQLTDFGDDSKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLTA
>A0A0H4PHR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclobacterium amurskyense|TrEMBL
MKVTDYLKNTDKTHFSFEILPPLKGQSLTNLLDGITPLMDFNPPFIDVTYHREEYMYKKH
ANGLLEKISTRKRPGTVGICAAIMNKFKVDAVPHLLCGGFSKEETENALIDLYFIGVENV
LALRGDAPKSEANFIPNKDGHKFASELVGQIIGMNEGKYLHDETEIGFQTDFCVGVAGYP
EKHFEAPSLNFDLKKLRAKIDAGATYIVTQMFFDNQKYFDFVEKVREAGIDVPIIPGLKP
ITTLSQIVNLPKTFFLDLPDDLMLELEKCKNNAEVKEVGIEWAIHQSKELVKYGVPTLHY
YTMSKADTTYKVAKEVF
>A0A365P1X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium tibetense|TrEMBL
MKVTEHIQNANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
MPNGLLQKKIVKKRPGTVGICAGIQNKYEVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGHAYASELVTQISNLNNGIYLDEDLQNSTKTDFCIGVAGY
PEKHMEAPSLDSDIHFVKQKIKNGADYIITQMFFDNKKFFDFVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMEVVKAKDNDAVKQIGIEWCAQQSKELVAAGIPVLH
YYSMGKAENVKAIAREVF
>A0A2E8IRF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadaceae bacterium|TrEMBL
MSKERRYSFEFFPTKTEAGHEKLLATARELATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVETAPHLSCVGDSKAELRELLALYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VSFIREETGDQFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVDRVRKMGIDLPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIESIQAYG
EQVITEMCERLLQGGAPGLHFYTLNQSAPSLAIWNNLKLPR
>A0A4D6XKS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MNVFSQYHQDIIKQKLENISNNIQCSFEFFPPKKSSLEKNLLSSVQHLSELKPNFFSVTY
GANSGEREKTYDIVKKIYKKTGIITAAHLTCVNSTPNKLKKIAEHYWKNGIKSIIALRGD
TLEKNYKHTMYALDLVILLKKIANFDISVAAYPELHPESKNLKLDILNLKKKVDAGASRA
ITQFFFNIESYLRFRENCIKNRINIEIIPGILPVCNFKQLQRFSKMTNVHIPKWMFQMFD
GLDNDVFTQKIIGSSIAIDIVKKLSFEGVKNFHFYTLNQSDMTYSICNILGL
>A0A7V9U999|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriales bacterium|TrEMBL
MSEAMLTPAVGEVPSVMAEDRARAALVGALQRPRYEVLPLAATADQVQEHVPTHIPITVT
ASPRRGIEPTLALAETLAGLGFAVVPHLAARLFADESQLAETLHRLDEAGVRNAFVVGGD
SELPVGDFPDAVTLLAAMQRLRSDSGRGHCLDQVGIAGYPEGHPLVSDEKLSESLAEKQS
LATYVVTQMCFDPKVVSRWVSQVRRIGVRLPVYVGVAGKIDSRKLMEVSARIGIGGSARF
LRKHRHAWARLLLPGAYRPDRLVRELVSELAEPSRGVVGLHVYTLGAVASTERWRQQALD
RLTGDGDR
>A0A6G7IYA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda oceani|TrEMBL
MKITDHIKKANGETLFSFEIVPPVKGKSIQELYKNIDPLMEFKPPFIDVTTSREEYIYKE
KDGLLDKKLTRTRPGTLGICASLKHKYNVDTVPHVLCGGFTKEETEYLLVDCQYLEIENV
MALRGDARKEEKYFTPTKGGHQFATDLVKQIQDINEGNYLHDTIKSSDLTSFCIGVAGYP
EKHMEAPSLQSDLKRLKQKVELGADYVVTQMFFDNQKFFAFVKAAREIGIDVPIIPGIKP
IAVKRHLQLLPHVFSIDLPQDLIDAVEACKDNKEVRQVGVEWAIQQSKELRDAGVPVLHY
YSMGKSDNVKAIAKELF
>A0A8J7BHX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nodosilinea sp. FACHB-13|TrEMBL
MGYRLRTAAQAGQFLVTAEVMPPKGGNPEHMLAMGQMLKGRVHAVNVTDGSRAVMRMSSW
AASLLLQQQGIEAVCQVACRDRNRIALQADLMGVHALGLRNILALTGDPVKAGDHPEARS
VFDLESVRLLKLLEKLNFGVDSNDKPLTDGALDLFAGAAIDPQSTSWSGLQRRFEAKVKA
GAQFFQSQLITDFDRLAKFMDQVASGYNRPVLAGIFLLKSAKNANFINRNVPGVNIPQAT
VDRLAAAADPLQEGVKIAAEQVQAAQQICQGVHLMAVRREDLIPQILDQGGVAPVDAALA
ER
>A0A8J2FAG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amoebophrya sp. A120|TrEMBL
MMSSTSSTSALARRRIGEIFQQSALAPATSSSSSSSTTKPAAVFGVEFVPADDKTVVAQR
ISRTQKWQPAWVGVTWHVTQADQSRKTLQLVQNLTQNTELNCMMHLTCRDMTKTQIREVL
DQCKALGVRNILALRGDGMTAGTPKGDHGGATTSTSSSPVTTEAAVEGTGCEVDDKNVVN
KNHSDQQFQYAIELIQFIRTEYGDFFGIACAGYPEMHPDSKQDLEKDIFFLKQKVAAGAD
VIITQFFYDVGKFFEFKIQCRKSGIECPIIPGIMPITSYARLGKINRWNPTAAVPAALRE
ELEKRKEDGAALRAFGIEECVRSCRLLLEEEYGAAEGEKFLPGLYFFTLNQDDVIHEILK
ALKLVE
>A0A7G9WKU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caproicibacterium amylolyticum|TrEMBL
MITKSLFYDHTVFSFEIFPPKRTAPINTVYHTLESLRELCPDFISVTYGAGGSAINSATL
QIATDINQKYGVESVAHLPCLYLSRKQAVQRVKELTESGIENILALRGDAVPNKRPLRDF
AHASDLIAFLKGFDKFHIMAACYPEVHPEAPDMDTDIQHLKEKTDAGASHLISQLFLDNS
CFYTFLQKVRADGITVPVEAGIMPVINKKQIQHMVSLCGASLPEKFRTMMDRYEDNPEAM
RDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPLVAHKIHEATKTLFQH
>A0A514LDJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salicibibacter halophilus|TrEMBL
MKFLDKLQNEILIGDGAIGTLLYDRGHSGSIEDANRHAEEMVVSAHQEYIEAGANVIQSN
TYAANQLKLMNYGLEHGMGEINAQGVRLAKHAAKGKNVYVAGTIGGIRDGRASPFNNQEI
KAATQSQAEALLSEDPDVILLETYYDLHELVQAVRVIKRLSPDMPVIGNVSLGDVGVLHG
GIPVNDALLRLWNEGANVIGINCRMGPAQTIASLEEISLPEGAYLSAYPNASLPGIQDGR
LVYQSNPDYFKSQAEEFRKQGVHLLGGCCGTTPEHIRSFTEKLQGQSPAVKERTKVSAVR
EQASAEVGDTLQLDKKDPSIIVELDPPKSLTKMDKFLNGAQTLHEAGADAVTLADNSLAT
SRIDNLAASTLIKQQAGAHPLLHIACRDRNLIGMQSHLLGLHALGIRDVLAVTGDPTKVG
DFPGATSVYDLTSFDLIRLIKAMNEGFSHSGRPLGLQTKFTVGAAFNPNVSSMAKAVKRL
EKKIVAGADFVMTQPIYDVETLHQLKEATAHLDIPIYVGIMPLINGRNAEFLHNEVPGIQ
LTEQVRKRMAECGKDVQKGEEEGMAIAKELQGASLELFGRIYLITPFLRYHITAALTSDI
KTRSAQQMRFS
>A0A846E884|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desertifilum sp. SIO1I2|TrEMBL
MSKLRSAIQAGEFLITAEVAPPKGGDPAHMLEMAKLLKNRVHAVNVTDGSRAVLRMCSLA
ASALLQQQGIEAVCQVACRDRNCIGLQADLMGAYALGIRNILSLTGDPIKAGDHPQSKGV
FELESVRLLQLIDKLNHGIDFNDQPLVDGTVELFAGAAVDPQCGSWSGLQRRFERKVEAG
AQFFQSQLITDFERLDKFMTQIASASGKPILAGIFLLKSAKNAQFINRCVPGVQIPDSII
ERLAKAEDPLQEGVKIAAEQVQLARQLCHGVHMMAVKREDLIPQILDLAGISPL
>A0A803KU04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chenopodium quinoa|TrEMBL
MKVIDKIKASESSNQTLFSFEFFPPKTEDGVENLFERMERMVSHSPSFCDITWGAGGSTA
DLTLEIANRMQNIVCVETMMHLTCTNMPVEKIDHALDTIKSNGLQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHMRKKYGDYFGITVAGYPEAHPDAIGENGLATPEAYASDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYRGFIRMTGFCKTK
IPQEITDALEPIKDNDEAVKAYGIHLGTEMCKKILASGIKQLHLYTLNMDKSALGILLNL
GLVEESKIQRPLPWKRPANVNRIKEDVRPIFWANRPKSYITRTKGWDQYPQGRWGDARNA
SYGALSDHQFMRPRSRDKKLQEEWAVPLKSIEDINEIFKNFCLGKLKSNPWSEIDGLQPE
TKIIDEQLSNINKKGFLTINSQPAVNGERSDSPTVGWGGPGGYVYQKAYVEFFCSREKLN
ALVEKCKGLSHITYMSVNKGGDWISNVGQTDVNAVTWGAFPAKEIIQPTVVDPASFMIWK
DEAFEIWSRSWAQLYPEGDSSKKLLEEVQNSYYLVSLVDNDYVSGDLFSVFATL
>A0A009FZ59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 348935|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
DRIQKAGIDSPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A3C1CZB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp|TrEMBL
MRVDEVFKQAASQGTTPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITGEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAS
ENDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACENLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A519ELF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYAQQPEFCSVTYGAGGSTHEGTFGAVREILAE
GVDAASHFSCIGATKATVRTQLGELKAMGVRRLVALRGDLPSGYGVGGEFGHASDLVAFI
RQETGRDFHVEVACYPEVHPQARSPEADLQAFASKVKAGADSAITQYFFNADAYFRFVDD
VRRLGIDTPIVPGVMPITSSTQLMRFSDACGAEIPRWIRLRLQGYGDDTASIKAFGLDAV
ATLCERLRAGGAPALHFYTMNQATATLALLDRLKGSA
>A0A1L5NK12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium gallicum|TrEMBL
MALNTGDRRNIGISFEFFPPKSEEMEGQLWKTVAELQSWDPDFVSVTYGAGGTTKAPTLT
AVTRFLNETPLATASHLTCVGATKEETHQVIDHFRKAGVKHFVALRGDAPGGAGVPYQPH
PGGYANAAELVAGLREIGDFEISVSAYPEKHPESRDVAADIDMLKRKADNGADRALTQFF
FDNDNFERYLEKVRAAGVKIPIVPGIMPIQNLTQLKRFASACGTVIPAFLDERFAGLDDK
VEERAKVAVDVAVEQIEDLVRRGLDEFHLYTMNRSPLVSAVLTNLGLRREGAKRAAGAAA
>A0A396RR72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas gilva|TrEMBL
MTPTFGQLEEARRALDAPLFADLAGDAQVSFEFFPPKTEKMEETLWDSIQALAPLCPRFV
SVTYGAGGSTRERTHATVARIQRETLLSAAAHLTCVEATKDEILAVADEYWAAGVRHIVA
LRGDPPTAGAKFVARPDGYAGAADLVAGLRARHPFEISVAAYPECHPEAADAAADIDNLK
RKLDAGATRAITQFFFSPETFFRFRDAAAKAGVDREIVPGILPVSNVAQTRRMAGMCGTE
IPDWMGRLFEGLDDHPGARALVAATIAAEMCRKLYAGGVRHFHFYTLNRAELSFAICHLL
GLRAKAVAGEKAA
>A0A4Y6V0L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharibacillus brassicae|TrEMBL
MGMLDELRTRVLVADGAMGTLLYLNGIDRCFEELNLTRPEQVRQIHQAYLGAGAEVIQTN
TYAANDHKLKRYNLEYELEAINRAGARLARSAAEGTGAYVLGTIGGIRSTKPGEVTLGEI
KRSNERQIESLLGEGVDGLLLETFYDPEELRSTLTLARQKTDLPIVAQVSTQDSGFLQDG
STLTEMFAILEGLGADVVGLNCRLGPFHMTRYLKQVPLPKHAFLSAYPNAGLPEYNEGRL
RYRSGADYFGRSALELRGEGVRLIGGCCGTTPEHVAAMVEAVKGAAPITEKTTERSDDAE
PVPFGRIEVREKAEQLSAAQEGPPAEIPFHAAAAAKDHSVIVELDPPRTLRTDGFFKGVQ
ALKEAGIDALTLADNSLASPRIANESLASVVKEKYGVKPLVHVACRDRNMIGLQSHLMGL
AASGINQMIAITGDPSKVGDVPGATSVYDYNSFDLIKLCKQFNEGRLPSGRSLGLRANFS
VGAAFDPNGRHLEKGVQRLEKKIAAGADYFMTQPVYDERRIEELYHATKHIKQQIFIGVM
PLISSQNAAFLHNEVPGIRLTDEILARMQRHEHDKEAAMQEGMAISRSLIDAILEYFGGV
YIMTPFLRYEQSAELTRYVHEAAGKRALIQSRPAR
>A0A1E5LC33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus solimangrovi|TrEMBL
MKLLERLKDEILIGDGAMGTLLYSYGVDFCFEELNTSQPERIEQIHLAYLKAGSDVIQTN
TYGANYIKLARYGLEDQVKKLNEQACRIAKRASKTKEQTHVLGTMGGLRGIRKQDITLTE
VKRTFREQLYPLLTEDVDGLLLETYYDFTELKTVLEIARKETDKPIVAQLSLHEVGVLQD
GTPLAEGLKQLAELGANVTGVNCRLGPYHIIQSLEQVPLLDHAYLSAYPNASLPDYVDGR
FIYESDASYFEQCALDLREQGVRLLGGCCGTTPEHIQAFHSKLKGQKPVSEKVIKPFRSE
ITVQQTKREEVPLQDIAKERRSVIVELDPPKHLDTQTFFEGTKALKEAGIDALTLADNSL
ASPRISNTAMATIAKNEYKTRPLVHLTCRDRNLIGLQSHLMGLHTLGLHDVLAVTGDPTK
VGDFPGASSVYDLSSFELIQYIKQLNEGVSFSGKPLKQKCSFSVGAAFNPNVRHLEKAVQ
RLEKKIEYGADYFISQPIFSRVQIEEIYQATKHLTTPIYIGIMPLVSSKNAEFLHHEVPG
IKLSDQTRERMVKCGTDKESAQSEGIAIAKELIDTAMQYFNGIYLITPFMRYKMTATLAH
YIHQKDNSSIERKVHHV
>A0A1I1I969|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinospirillum celere|TrEMBL
MSHLSVPISYEFFPPKTSAGQEKLLRVGEQLAASQPEFFSVTYGAGGSTQDGTLQTVLDL
HQQTGIEAAPHLSCIGATRQELRERLQRYREKGIKRLVALRGDLPSGMGMGGELRYANEL
VEFIREEFAQDFIIEVAAYPEAHPQAPSFEADLQNFIRKCKAGADSAITQYFFNADAYFY
FVERVRAAGIELPIIPGIMPIMNYTKLARFSDACGAEIPRYIRKQLEAYGDDSESIQKFG
EEVVSRLCQQLLDGGAPGIHFYTLNQAAPSLNILKNLK
>A0A094FY75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4518|TrEMBL
MADSPTTDKITDKIAALPHDASYFSLEFFPPKTAMGTTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSRALVDDALSAAKEAGIQNILALRGD
EPRGEYKDALEEGKEGEDEFVWAIDLVRYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
EHDLPYLVDKVQAGADFIMTQLFYDVDAYDKFEKILRDHSSGAFKTLPIIPGLMPIQSYQ
ILRRTTKLSNAKLPQSIIDRLDAVRTDDEMVKKVGVDILAEIVESVKATKKRTQGPKGFH
FYTLNLEKAVAFILERANLIPSFTPVLTSDVFAVDDITDTIPLPQLLINGERKNRRQSSV
GSGPHNFVIIDREEASGFEATGAEAAVPKEGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRPDITSIFVQYLNGTLSALPWSDE
PITAETNLIKDELVKLNQKGWWTIASQPAVNGARSQDEVVGWGPKGGWVFQKAFVELFVP
TSDWARLKPLLEGNEEVSFLAQSASGEFLKSKLDLGPGEEGSETNAVTWGVFPGKEIVSP
TIVEEVSFRAWAEEAWQMWGEWAAVFGKSGEESRRFLDGVARDGWLVNVIWHDFVGMCKA
KEGRSEEEGYKGLWDVLIEA
>A0A5Q2QFR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoricola lipolytica|TrEMBL
MHLPAHERRNRLEHRFGARKPPKVSFEFFPPKSEKAEASLWKTVDRLKGLSPEFVSVTYG
ADGSTRERTHDVVKQLSDNSGLATMPHLTCVGADQSEIDDIADGYWDMGVRRIMALRGDP
VGGAGEKYQPHAGGYPYAAELVSGLTKRHDFEIAVAAYPEAHPEAPSARFDLDNLKRKFD
NGASMAVTQYFFDTDVYLRFRDACVLAGIEKPIIPGILPVTNYATTKRFSDACGTKVPDW
MADAFDGLDNDAETRNMIAANIAIEQVLALQAEGIDEFHFYTLNRADLCFAVCHALKVRP
GKTAPNDPESTNWRLAGY
>A0A540TWN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira noguchii|TrEMBL
MKKVSEIYGSTKGPVYSFEFFPPKTPEGDLKLMETVKELSLLDPDFVTVTYGAGGSTRDK
TAQILSQISKNYSVPTVSHFTCVGANKGQILETLKGIRSSGIVNLMALRGDPPKGEGEFK
KVENGFGNATELISFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVKNLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A0L0AJ85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. RIT-PI-a|TrEMBL
MSHDRPLSFEFFPTKTDAGHEKLMGVARQLAAYKPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVNVPAAPHLSCVGDSKQDLRGLLDQYRSAGIKRIVALRGDLPSGMGMSSGELRHANDL
VEFIRAETGDHFHIEVAAYPEMHPQARNFEDDLVNFARKANAGASSAITQYFFNADSYFY
FVERVQKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLGR
>A3J2A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteria bacterium BAL38|TrEMBL
MKVTEHIQNANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LENGLLQKKVVKKRPGTVGICAGIQNKYQVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGHAYASELVTQISNLNKGIYLDEDLQNSTKTDFCIGVAGY
PEKHMEAPSLDSDIHFVKQKIKNGADYIITQMFFDNKKFFDFVKKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSIELPDDLIMAVVKAKDNDAVKQIGIEWCTQQSKELVAAGIPVLH
YYSMGKAENIKTIAKDIF
>A0A1Z9CBW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium TMED111|TrEMBL
MALFGLKTKHSQAPQVSQNLELFLKNFSIEVMPRTAEKVENFKDILPKNTRVYIAHIEGT
PIEDMVDTARRLAEDGFPTMPHFPARIISNKAMLNDWITRYQGEAGVDQALLLAGGVSKP
HGEYKSSMELLETGLFDKANFKNIHIAGHPEGNKDIDPDGSRKNVDAALKWKQNFKNKTN
AKMAIATQFAFEAGPIIEWAKSIKAAGIDIPIHIGIAGPAKLQTLIKFAIACGVGPSLKV
LQKRATDVTKLLLPYEPAEVLSQLADYKANNPEFNISSVHFFPLGGIKTNAKWVTENGGA
SGIPANQV
>A0A417QMZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea sp. OM07-5|TrEMBL
MKIKDILKEKTPHISFEVFPPKTDAGFASVLSATDQIGALKPSYMSVTYGAGGGTSKNTV
NIASHIKDDLGLTSLAHLTCVSSTKEHVARVIDELKKNNIENVLALRGDIPKESEFPLPN
HYRYAYELVEEIKSKGDFCIGAACYPEGHVEAEHKKDDIYNLKKKVDCGVDFLTTQMFFD
NTIFYNFLYRIREIGIAVPVVPGIMPVTKGNQMKRISEMSGTVLPQRFRDVLDRFGEDPK
AMQQAGIAYATDQIIDLFANGINHVHVYSMNNPAVATAIMHNLSDIVKNG
>A0A552EZD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa Ma_MB_S_20031200_S102|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAIFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>A0A0B2UCM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter oleivorans|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLRIVHQELQPLNPDFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIRQHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>R9XAP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ashbya aceri|TrEMBL
MSKIDAKYAELNRPSLSLEFFPPKTDSGKSNLLARIERMSAMDPLFITVTWGAGGSTAEK
TLELAALAQRELNIPVCMHLTCTNMDRQILDKALLRAKEAGIRNILALRGDMPLAAEEEE
HVDGGFLYAIDLVRCIKMQYGDYFCIGVAAYPDGHCEGEADGMEQDPMRDLPYLKEKVEA
GASFVITQLFYDVEKFLAFEELFRREISETIPVFPGLMPINSFMLFNRAAKLSHASIPSH
ILDRFPHHIRHDDLKVKEIGVEIMVEIVNQVWERTGGRIKCFHFYTLNLEKSIAQIVTQS
PVLSRIIEEDSETEDGDGDVIVEDANAAGADDLSYKKRRRQSSMQGEPESGMVMLDGPRR
FSVRGAVPSRKVVISISKGSGTLGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSLKVSNK
KAYQIWGYPSTLNDIKSLFIGYLEGSIEALPWSDLGLSPETALIQEELIGLNQRGFLTLA
SQPATNSTPSADKIFGWGPPGGVVYQKAFVELFVEKTRWETELRPRLEGPDSKFSYYFGD
SAGSFSSNMAPESSSVVTWGVFPNSQILQTTIIEEESFKAWRDEAFSIWLSWSKLFPRNS
PQNAFLRGIHKDYCLVSIVHHDFSNVDELWETLLR
>A0A8J6BWR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zizania palustris|TrEMBL
MKVIEKIQEAAADGQTVFSFEYFPPRTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDT
FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIKGVVGATPEAYSNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTK
IPDEITAALDPIKDNEEAVRAYGIHLGTEMCRKILASGIKTLHIYTLNMEKSALGILMNL
GLIEESKVSRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWVVPLKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINLNGFLTINSQPAVNGEKSDSPSVGWGGAGGYVYQKAYVEFFCAKEKLD
QLIEKTKAYPSLTYIAVNKDGESFSNILSNAVNAVTWGAFPGKEIVQPTVVDSASFMVWK
DEAFEIWSRGWACLFPEDDSSREILDKVQKSYFLVSLVDNDYINGDLFAVFKEI
>A0A0K8JF18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionispora sp. 2/2-37|TrEMBL
MIREYVAKNMVIADGAMGTYYASLKGTTVVFSEPANLTEPELIESIHKQYIAAGARLIRT
NTFSANTLSLGVTQAEVKQIIQAGYRIAAKAAAGRDVFVAADIGPVPALVSGADDIDHDR
IMAEYRFVVDTFLAEGAAIFVFETFSSTEYLGEISTYIKRQNKAAFILAQFATTPDGFTR
RGISNASIVSEAKNLTAVDAYGFNCGVGPTHLYNAVKKLNHRFAGNIISVLPNAGYPEVI
NERTVYAQNPEYFAEVMKNISALGVKIIGGCCGTTPEHIACLVRKLSQQPSVVEPSQPAN
GKANVTVKTVHNNFSAKLQQGEFVVAVELDPPFDTGIDKILDNAKVCRRIGVDLVTVADS
PMAKARVDSIMLSAKIQRETGMETMPHICCRDKNLNALKSSLLAGHIEQIRNVLAVTGDS
VSAADKTEIKSVFNLNSFKLIELMNRMNREFFADDVINIGGALNLNVPKPELEVARMVKK
AEKGAGFFLTQPIFSSEAIDFLPTVKKPSQVKILGGIMPLVSYRNAMFLNNEIPGISIPE
EHIHRFDPAMDRAEAEQAGIALAVEIARKIKPYVDGFYFITPFNRIEMVAKILQEVG
>A0A6J2ESV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zalophus californianus|TrEMBL
MDHPTPKVLPARPRGPSLGMWALETGRVRFSVPPSIRNPAMVNEPRGDGGPPPRSEGSSS
GSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRFD
RMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQEQITGY
LHKAKRLGLKNILALRGGVEAALYSLGSCFLEGLFCPYPVGDQWEEEEGGFSYAADLVRH
IRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGVTCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFARYLSGEPNQHGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPTPERGEEALGSCTVV
SLP
>A0A858RRU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteolibacter luteus|TrEMBL
MHIRDILSGKEAKFSFEYFPPKSPQAAENLFRTISELQLYDPAFVSVTYGAGGTTRAATH
DLVLRLLRETRVNTIPHLTCVGHSEREISALLESYAEAGVSNILALRGDPPKNGAGAAGD
FPYAADLVAFIRRFSQRHGHDFGIGVAGFPEGHPSTPNRMRELDHLKAKVDAGADYICTQ
LFFNNGDFYDFRDRCELSGIGVPILAGIMPVTSLGGLDRMAELAAGARFPAKLLRALARA
NGDDAVVRRIGIHYATTQCADLLDHEVKGIHFYTLNQSSATVEIFNQLGLRRSDLVTA
>A0A5A5THW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyobacter arantiisoli|TrEMBL
MQTHYPFLERLRHGPLLCDGGMGTELYARGISYERCFEHLNLTNPELIKSVHLDYVAAGA
QIIETNTFGANRYRLAEHGLEDQVYEINRAGAKIAREVRDLSEQPIFLAGNIGPLGSPLA
PIGKIQPDEAQTAFLEQTEALLQSGVDLLIIETMSDLTEMSEALTAVRSLTDLPVVALMT
FGEDGTVTSGEDAPTVARTLRDLGANVVGVNCAMGPASMFDVAQDMCAYTSEDFFIGVQP
NAGLPRRVGNRFIYVSTPEYFADYTRRFLKAGIRMIGGCCGTTPRHISAMHDVLTELAPT
TTITTDLIPASTPTLEALRERIQETATAGTPAQPAPTHVAQLLQDGKFVISIEMSPPRSV
KFTRFLQNAILIRDSGADAINITDNAMARVRMNNVAAARLIQQNVGIETIVHFTPRDRNL
MAVQSDVIGAHATEIRNILAITGDPPSHGDFPNSTGIWDVDSIGLISILHNLNLGLDGNR
RKLAAASSFFIGCAANPVAPDLDVEMERLHRKIENGARYIMTQPVFAAETFLSYKQNYEN
RYGQIPIPILIGLQPLHSYQQAEKFHNEVPGIVIPTEIRNRMREAGDTGSTVGLDIIKEL
FDNLAPAVQGAYIMPLDRYELITELIPYIRQRTQSPYART
>A0A5P1V342|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacterium sp. TA1|TrEMBL
MRFRSHLERVLKSGYMAITCEFAPPKNASLEPLKKKARVLKGYVDAANVTDCQVAMVRLS
SLAGCLALMSEGIEPILQMTCRDRNRIAMQSDLLGAWALGIKNLFCTTGDHPKFGNHPEA
KPVFDLDSVQLIAMVNKLKEGKFLNGEEIKGERPAYFLGATENPFADPTEYRVRRLAKKI
RAGAEFIQTQLVYDVTKFKQFMYIAHNEGLTEKAYILAGIVPPKSFRMIEYIKSNLPGSC
VPEDLVKRMREAKDPLEEGIQIAVELIEKIKEIPGVRGFHLMAIGWEEYLPEILKKTGFY
PRPLPPEDLVEEQKIFSFKDEDKRQLEEEIKNLKAHLLRLETLITGKKEEPVKERPLEKP
VVSVMPKEPVLVKEPEAKTSAPKPEPIKIIKGEYRSVSERIRGLPEELYRELSSGKIREI
FFGKGDKALNVGGAEVLPFHGFEGNLGQPLKVAMEVLDVVPEDYPEVVAKYFRDVWHDPG
AWAKKCVEEYGAEAICVYLLGTDPNYLDLGPDHAKKVIQKVREAVEVPLIIWGSDNPEKD
TEVLKEVAEVIKDDNVFFGPIVEENYRTLGAVALGYQLPVIAQSPIDVNIAKQLNILLEN
LGVPLEKIIMDPSVGALGYGLEYTYSVMERIRLAALYANDQKLQNPFICNIGREVWKTKE
VSLPSDELMGEAEMRGVMMETITALCLALAGGELFILRHPKTVALTKKMFSLFWT
>A0A6I5FIL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7803|TrEMBL
TYAADLVRLIKEAGDFCVGVAAFPERHPRSEDWDTDVRHFVDKCRAGADYAITQMFFDPE
AYLRMRDRVVAAGCDTPPIIPPEVMPVTNVRQLERLSQLSDAKLPDDLKERILAAKDDPP
AAVRSIGIDFATRFSAKLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A2D3VJC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp. UBA12504|TrEMBL
MFDTLIDKLQNSTYITLETTPGHSPQFVPIIDKIQELGLEKLVDGFSTTDNPLAKLKYNA
LFAAKMLQERFNKPVIATMSMRDRNKIALQSDLLGANEVDIRAILALTGDPATLSDQPHA
KGVFEGDSSLLLDIISAFNSGMNYAGKPFAFAPEHIYPFAVINSYAKNPKTLQKKMQKKI
KHGAIGIITQPVYDLEGAKQLIELKELANKEVSNENKSAELILGVFPITKLRTAQFLSAH
VPGINVPNYWIEALRNAHDKGAEEEYKVGFELSKNLFDSLKSYHPKIHLMTANQFQIAKD
ILL
>A0A089WRN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cremoricolorata|TrEMBL
MTVLKNALQQGQFVCILEFVPKPSAQRFAQVAAMMARGGFCGWPLTVSIGDRVGSALDLS
PLDAYDCLPEPVPALLHFSGKDRERSELLAQLQRMDAAGLAQMLVLTGDRLHGHVPGQRP
VRYLESVAALGIIRQARPDWLLGAALNPFKYREEEGGAQYFKAAKKLKAGADFLDLQLGF
DMDKHVEALDWMQRQPQPRPLIACLLALTVGRAKMLGQVAGVTVSASMLAMLEAEAAVSK
AFAQARSVGRLALQIVELQRLGYAGVHLSGLHEAQQMDALEAAVQACQAQIRTPAAWQTA
WNEAWHMPGCAPVTFHPEQANWRQGQSHVQPSWREAARVKLLGGLHHQLFSASTPLGRGF
AWAVRRPFWQGRRGARWLHWLERRAKRPLVGCDTCGSCRLEQTVYICPETCPKGLANGPC
GGTQLNRCEFGDRECIHSVRYRTAKADPQAALASQALIDCVNVETRHRSSWPQWFDANRP
GEPR
>A0A8H6GUM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. conglutinans|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>R0BG02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster bolteae 90B8|TrEMBL
MKTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTRDDVLLILEQLKEQKIENILALRGDRTADREPAGDF
RYAADLVEFIKNHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFRERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFISMMERYGDNPIAM
RDAGIAYAVDQIVDLAAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>H5SS77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetothermus autotrophicum|TrEMBL
MESNLQRALESKRFVVTAECGPPKSADRKVIEEKAKLLKDWVDAANVTDNQTAVTRMSSL
AACAILKSVGLDPVFQITCRDRNRIALQSDILGAYALGIRNVLCLTGDHQSFGNHPQAKG
VFDLDSVHLLETVKKMRDEGRFLSGDELTGERPAMFLGAVENPFAPPYEFRALRLKKKVE
AGAQFIQTQIVYNIPRFREFMARAGDLGLLDRVYILAGVSPIKTPGAAKYMRDNVPGLDV
PNEIVARMEAAGKGIEDKKARAEAWRQEGIKICVEIMQQLKEIPGVAGVHIMAIEWEEAV
PQIVKQAGLKS
>A0A842A1T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTMPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVAEQIISQN
>A0A212PLG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp. DSM 9736|TrEMBL
MNFLDRARNEVLVGDGAIGTMLYSKGVSLDASFEHLNLVRPELVEELHREYLEAGAQVIE
TNTFGANRTKLGLIGLENKVEKINRRGAELARRAADAAGRSAFIAGSVGPLARPKGEEQD
LSPDDVLSVFREQCTALANGGADLFILETFSDLEQLKLALTAARETGLPAVASMAFLEGG
RTGGGIEVERMATALTEAGASLIGANCGAGPLEVLRNLERMAAVTEIPLAAYANNGFPEY
RDGRYIYRTTPDYFAERALEMASAGARLIGGCCGTTPDHIRRIAERLKGVRPGRRAVVIQ
VAAPESPRGAAEPSRGFLSGWGKQPVVTVELDPPRGLDCTKVIAGSRALKEAGADAINLA
ENPLARVRMGNIALASLIQREVGIEVIVHITCRDRNILGLQSDLMGASLLGIRSILAVTG
DPARLGEHAGATSVFDLNSFGLIKLLSDMNAGVNSLGSPIGAGTGFTIGAAFNPNTPRME
VQAARLAKKVANGAAFAQTQPIYDGKRLAEMLAHTEPLGIPVLPGILPLVSERNCEYLHN
EVPGIIIPDEVRRRMRGKEKEAGVQEGLNIAAEFISETKHSVGGFYLIPPFGKWEVAIEL
IRMIKGKKS
>A0A7D6JJ86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosynechococcus elongatus PKUAC-SCTE542|TrEMBL
MSVSGFQAACEQGEFLITAEVCPPKGRDASTMLRQAAHLKGRVHAVNVTDGSRAVLRMSS
WAAAYLLQQQGLEPICQMACRDRNRIALQADLMGIAALGLRNILALTGDPVKAGDHPQAK
PVFDLESVRLLRVIGQLNQGVDSEDRPLPDGATQFFAGAAVDPQSPSWSGLQQRFERKLA
AGAQFFQTQLITDFERLAKFMDQIAAGCGRPILAGIFLLKSAKNALFINRAVPGASIPQH
IIDRLAAAADPLDEGIMIAAEQVQQARQLCQGVHLMAVRREDLIPEILNRAGIAPLSASP
APRAKMPHNP
>A0A7X0XE62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRSLRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVTEQIISQN
>A0A7X6G1R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium A_SAG2|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGA
>A0A1I6M874|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulicella pectinivorans|TrEMBL
MTGTAVETTNKALDELFRAPDGETARRTVLCDGAMGTMLYDRGVFINRSYDELNISQPEL
VRAVHAEYLQAGAEIIETNTFGANAFRLERYGLRDSVRKLNLAGMRLARECVTQMREKQA
SEAYVAGALGPLGVRLVPHGPVSREDARETFREQVRALAEGGPGVGADLFVIETMMSMAE
TEEAMAAVKEEAPGLKLIVMLTVDDKGNSLDGTSAEEATRLMQLWGADAIGCNCSDGPQT
VLDVIQRMRAVTKLPLAAMPNAGIPREVDGRHMYMTTPEYMAGFARKAVKAGATFLGGCC
GTTPAHIRAMRHALRALGAMQEGVHAEAAVVIESTVKPPALKERSKVGAMIAAGDWITMV
EIVPPKGIDCTKEIEGARMLYKLGVDVINVPDSPRASARMAAQSLCVQIQQQVGIETIIH
YTCRDRNVLSIQSDLIGASSIGLKNVLCLTGDPPKMGNYPDATAVFDVDAIGLTKIVRGL
NHGLDIGNNPIGGSTGFAIAVAANPGVADLDFEVRRFEAKVEAGAEFCITQPVFDLQVLE
DFLRRIEGFRIPVIAGIWPLTSLKNAEFMKNDLKVRVPDQIMTRMGKASGPDAARAEGLA
IAREMLAEARLLGHMMVRGVQVSAPFGKYKAAADVLGLEG
>A0A069PEY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia grimmiae|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRASRAQLAKLSPKFVSVTFGAGGSTQQGTLDTVLEMAA
EGFEAAPHLSCIGSSKESLRAILGAYREHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQEHGDWFHIEVAAYPEFHPQARSPRADLENFARKVKAGANAAITQYFFNADAYFEFID
ETKKLGVDVPITPGIMPITNFSQLMRFSDMCGAEVPKWIARRLESYGDDRESIRAFGLDV
VTGLCRRLVDEGAPGLHFYTLNGAAATKTICERLGFGKA
>I4EZU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter marinus|TrEMBL
MTGTVRELLQTEQPTWSFEFFPPKDDAGEAQLWTALRQLEQLRPSFVSVTYGAGGSTREG
TVSMTERIATDTTMLPLAHLTAVDHSTAELRHVVSRLAAVGVRNLLALRGDPPGADPQAE
WVAHPEGVRHAAELVELIKGIGDFCVGVAAFPERHPRSPDLEFDTDMFVAKCRAGADFAI
TQMFFRVEDYLRLRDRVAARGCDVPLIAGVMPVTNARQITRIVELSGQAFPTELADRFAE
LDGDTPEHKRAVRAYGVEVATDMCRRLVAEGVPGIHFITMNRSTATREVFQALARADALS
GAARPPR
>A0A3B0BN58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus chosunense|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISSLQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLETCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2M9EKV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium NML95-0200|TrEMBL
MLPISFEIYPPKNDAQHAQLQRTLEKLKPYRPQFISCTYGAGGSTREHTAETVQLLSSEH
GLEGVPHLTCIGSTREEIIALLAHYQQQGVRRIVALRGDMPSGMLAPGELRHASDLVALI
RDAFGQHFHIEVAAYPETHPQARDALADIENFKRKVDAGADSAITQYFYNADAYFRFVDD
VRALGVKVPVVPGIMPISNFSQLQRFSESCGAEIPRWVVQRMRAFGDDGSAIREFAADLV
ASLCQRLLAGGAPALHFYTLNLARPVSNILKRLQ
>B4RL60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae (strain NCCP11945)|TrEMBL
MQINYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTY
GANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGD
EPAGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHV
ITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYE
GLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A6M7UIP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium erdmanii|TrEMBL
MTPRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A7I0RL77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. CGMCC 11546|TrEMBL
MRSETARRDGDIRLSFEFFPPKNAEMDAQLWETVAELKKWDPDFVSVTYGAGGSTKAPTL
DAVRRMIGDSHLPTAAHLTCVDASRDDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYQP
HPEGYENAAALVKGLREIGDFEISVSAYPEKHPESASETVDIDMLKRKADNGATRALTQF
FFDNDVFERYMERVTVAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFEGYDE
DLEGRARVAAEVAAEQIADLQRRGFNEFHLYTMNRAPLVDAVLENLGLQRLRRSAA
>A0A840XXT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas alkaliterrae|TrEMBL
MNQALSGTLARWLTGPRVAGLPAPAQMPAPRLSFEFFPPKTEKLEEQLWACIRRLEPLAP
RFVSVTYGAGGSTQERTHQTVARIVAETSLTPAAHLTCVGATREEVDAVARRYWEAGVRH
IVALRGDPPAGASRYEPHPGGYAQAEDLVRGLKRIADFEISVGAYPETHPAALSAEADLD
FLKRKIDAGATRAITQYFFDTETYLRFLDRCLAKGITVPIVPGILPVSNFQQVVKFSAMC
GASVPAWMGQLFEGLEEDVETRRMVAAVVAAEQVRLLQANGVDEFHFYTLNRPDLTYAIA
HILGARPRRG
>A0A8H7RPK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor saturninus|TrEMBL
MKVTDKIAKAEQEGRPFWSFEYFPPKTPQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
DLTTEIVATAQSVYGLETMMHLTCTNMPIKQIDDALEAAKNCGCQNILALRGDPPKGQEN
WESCEGGFEHADDLVRYIRQKYNDYFCIAVAGHPEGHIDNPDKEDDLLQLKNKVDAGADL
VVTQLFFDIDSFLTFYKKARAIGITVPILPGVFPIQNYTGLKRVISFNNNFVPQSIWDAL
EPIKDDDTAVKEYGINLTVEFVKKFREVGINGFHIYTFNLERSSRILLERLNLMAPVESV
KPLPWNPSLTTKRAKENVRPIFWKNRAKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
INLKYPVEQCIEMWGTPTTVDDIAQTFARYCKGQIAGIPWSAQQLDAETDIIRQRLAAIN
MLGYLSINSQPAVNGVKSSHKVYGWGPKNGYVFQKAYLEFFVSPEKLDELIEKVGKDHQV
TYYAVNKQGDLRTNTQSDEPNAVTWGVFPGKEIVQPTIVESVAFLAWKDEAFELWSKWAR
IYDRESESAELILDVTKSWYLINIVHNDFQDENGIWRLFDLEIDGEISRKLLNNVAR
>A0A1N6HWR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium scophthalmum|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICSAIQHKYGVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTLGGHASAMDLVNQINNLGRGKYLHDDEQICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVKKAREMGITVPIIPGI
KPIATKKHLKLLPQVFKIDLPEDLINAVEGAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKIAGELF
>A0A4S8N3M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium rhizophilum|TrEMBL
MTKTERPIANTSDLRISFEFFPPKSPEMDEQLWQTVEALQAYQPDFVSVTYGAGGTTREP
TLATVKRLITETPLSTASHLTCVGATREEVRAVVEEFQAAGVRHFVALRGDPQGGVGTRY
APHPGGYVNAADLVSGLRDMGDFEISVSAYPERHPESENDVVDLDMLKQKVDAGATRALT
QFFFDNDIFERYLERVRAAGITIPIVPGIMPIQNLTQLKRFAAMCGASIPAFVDARFEGS
EGDPRARAAIAAEIAAEQIADLSRSGLQDFHIYTMNRAPLTIATLERLGVSTQTGNVSGA
AA
>A0A017SPF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus ruber CBS 135680|TrEMBL
MEKLTDKIAALPPNSSYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AKRSLELAEVCQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNIHGEDDSNKDFMFAVDLVKYIRQQYGDYFCIGVAGYPEGHPADSFQDVQDPHQDLPYL
IEKTKAGADFIMTQLTYDLDAFNDYESLLRNHESGVFKTIPIIPGLMPVHSYKILTRVTK
LSYVKVPPRIAKKMEEVKHDDDAVKRVGMDVIIDIVEGIKKVASPGIRGFHFYTLNLEKT
VSFILERCNLIPEYDENAIEDGGALDVAASTLDVAPNGSRIGSKSRASSLNSQPRNRVIV
DRKQANLEDATRDSASHEASAVSAGMPAMPPNPSTTLQISEGLGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVPAPAARRLWGHPVSRSDLSTLFRRHVSGELHMVPWSEGGA
EEGSGGLNPETAVIRPELLKLIDGRGWWTLASQPAVNGVRSDHPVFGWGPQHEGFVFQKP
FVEFFCPNKDFQNSLKPVLVKHGHEKLAWFATNAKGDFESSLPAHPAGSDNDDIVEMNPD
NVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRVYPRGTPTERFLEDTKND
VWLVCVVAQEFGAGTEVGSSEEEKEVKWMWRVLAGEE
>A0A2R3JT90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus sp. CBA3606|TrEMBL
MNLRQALKQRVLVADGAMGTLLYGNYGLSSAFENLNLTHPDTILRVHQAYINAGADVIQT
NTYAANRLKLTRYDLQDQVVAINQAAVKLAVTAQQAADHPVYLLGTIGGLAGDTDQTVQQ
ATPAAITASLTEQLNALLATKALDGILLETYYDLPELLAALKIVTAHTTLPVITNVSMLA
PGVLRDGTTFADAVIQLAAAGAAVVGTNCRLGPYYLAQSFENLPIPANVQLAVYPNSGLP
GTNQAGQVVYDGEPSYFEEYAERFRQLGLNLIGGCCGTTPLHTAALVRGLVSRTIVPHSN
QGVPPIATPLTPTVGHHDFLKKVTQQKTVLVELDPPKDFATAHFFKGAQRLKAAGVDGIT
LSDNSLASVRIANTMIAAQLKLNYGITPIVHLTTRDQNLIGLQSEIMGLHSLGIEDILAV
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGNSLKQATDFRVAGAFNPNAVR
TTVSTKSIERKLAYGCDYLITQPVFDLEKVHDLAAALRARHLQIPVFIGVMPLVSKRNAE
FLHHEVHGIRLPVAVRARMAQAELDGNEAAVGLQIAKELIDGICTEFNGVHLVTPFNRFK
TIIKLVNYVQQKNLTVTK
>A0A350JDC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium|TrEMBL
MSILEHALNCRYSFEFFPPKSSVSSLALDTCLTGLATWQPEFCSMTYGAGGSSQAESFSA
IQRLQQRGHLTAAHITAAGASTVAINKTAQTFVQEGVDHLVALRGDSPSGPFIPHPQGYA
YGADLVAGLRHWFDGTISVAGYPETHPDAPNVNADIGHLASKVAAGASQIMTQYCYDTET
LLRFSDRVRGLAITVPIVVGIMPIHDIVAIQRFSARCGATVPANIVAPFERLSDANDQFK
LAIEFAVKQIEQLAEQGLDQVHLYTLNRPQWAHGILHALKPAKLAKSA
>A0A8J3SPP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planobispora siamensis|TrEMBL
MPTVRELLAAGGRSFSFEFFPPKTDEGERQLWRAIRELEALRPTFVSVTYGAGGGTRDRT
VEIVERLAHETTLTPVAHFTAVNHSIRELRHLVGRFAGAGVRNILAVRGDPPGDPMGEWV
RHPEGVLYAEELVRLIRQSGDFCVGVAAFPYKHPRSVSVESDTEYFVRKCRAGADYAITQ
MFFRAEDYLRLRDRVAAKGCDTPIIPGIMPVTQMSTIARSEQLSGAPFPPEVAARFEAVA
DDPVAVRRLGVEHAAELCQTLLDEGAPGIHFITFNRSSATREVFQALDAARETAPLTA
>A0A6P0CDF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sediminilitoris|TrEMBL
MPTPNVSFEVFPPRSVDAAFNLWDTAQALAPLSPRFFSVTYGAGGTTRDLTHDAAHVLRR
TSGLPVAAHLTCVGASKAETLEVADNFSKIGVKDIVALRGDPQDGAETFTPHPDGFADSC
ELIEALAQKGTFNIRVGAYPDSHPEADSQQANVDWLKRKFDAGANEAITQFFFEAESFLR
FRDACAAAGIDKPITPGILPVINWKSARKFATRCGTPIPQWLDDAFEAAIRDDRHDLLAT
ALCTEMCSTLIDEGVEDLHFYTLNRAELTRNVCRALGVTPQVTLEDVA
>A0A7K8IP70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetorhynchus papuensis|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLRDKMRRRQDAGDK
WFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFDYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKTPREELL
KMWGEELTCEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLDNCLWQVVEDTFELLN
>A0A0E2BKK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira santarosai str. MOR084|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSRLDPDFVTVTYGAGGSTRSK
TAQILSEISKNYSFPTVSHFTCVGANQEQILKTLKEIRSSGIVNLMALRGDPPKGEGQFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPNAKNLEEDVENLKRKVDAGADFLVS
QLFFVNSIFENFLNLVRAAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A3ZZ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastopirellula marina DSM 3645|TrEMBL
MNLADYYSPGRLGLSFELFPPKTDKGDASLMLHVEKLVKFKPDYITCTYGAGGSTRGKTL
DIVEKVKQVFGVPVASHLTLVDSTVGDLRLYLAEAERRGVDYIVALRGDPPQGQTKFRPT
AKGLSYASELVELIKDEFQEFGVAVAGYPEKHQEAESLDVDIDRLKHKVDCGADIIITQL
FYRNQDFYAFREKCAAAGITVPIIPGIFPIVNGAQIQRIATMCGAKFPRALVEALQKKPE
DTDYHMQVGVEYASKQIEELTEAGIPGLHFYVLNRSEATAAILANVRYAKSRS
>A0A1G0YZG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_44_16|TrEMBL
MEFCRSSGFKNFVPVSGDGVSGENIKQTRKHTFTEGIHLLRRMKSQDDSTLFGGCAFNPF
KYTPCDHFTQYFKLIKKINQGANFLVTQFGWDMLKLQELRWYLSSRGLYQPSIARLLLLT
PEWVEQISAGKCPGVHISPDFQGILKKEVNYSYKQFEAAQWRRLQIQAAGCKLLGYSGVQ
IAGLKNAEQVSIACNMIVEALSEFKTFESWKNEYYEHLARAEMAPYPHRFYMFDKLFSEA
HVDEFPSMKEGKIPQCSGSEKLHYKICEFLFSHASCQDADEHLITKKIFAGCRKCSFCRL
PLTHYICPELCPKGLSNGPCGGSRADGSCEFGEMECIHSRRMRLASWLNEIDSLEEHYIK
SAEKYSKAKK
>A0A3R9FMU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atlantibacter subterranea|TrEMBL
MSFFHANQREALNQSLAEVAGRINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIARDYWENGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFS
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPTV
>A0A1J4PUK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces malaysiense|TrEMBL
MNPAATAPAAVGTALLDDFSLEMTGKDVPALEEARDSIPRGTRINVTFLAGEDHATRLAA
ARAVRRLGFVPVPHISARRLPSRAALEDFLAGLAEDGTADDVFVVGGDPARPEGPYEDAL
AVIRTGLLERYGVRHIGISGYPEGHPAISGSALWSALTDKAAAIGAGPFAGDVITQFGFD
AEPVLDWLTAVRARGVDLPVRIGVPGPAGIRRLVGYATRFGVTTSASVARKYGFSLTNLL
GTAGPDRFLHALGERYDPARHGVVKVHFYTFGGLRATAEWVGQFRERAR
>A0A318NPW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora arborensis|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTEVGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATDTTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWIRHPEGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAQFVR
KCRAGAEFAITQMFFEADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PSALAARFERVADDPEAVRRLGVEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLK
VGARL
>V5TU83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter malonaticus|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASPDELRTIARDYWNNGIRHIVALRGD
LPAGSGKPEMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVAA
>A0A1Q7IR89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_1_40CM_4_65_12|TrEMBL
MHIAEMLDRGRPTVSFEFMAPRDENEVQVLEKTVAALAGHAPDWVSVTYRLRTGQETLEL
VTRIKRQYHIEAMAHLTCANTRDATRRILNWMEREGIANVLALRGDPPGPGQPFQPADAG
LTHGSDLVAFVRGNGYRLGIGAACSAEKHPESPDLEHEFHYMRLKVEAGADFLITQLFFD
NRFYFDLVARARTAGIKVPIVPGLMPLPSRRSLAFVTEMSGASVPEPLQRAIDAQPDDEG
IRKLGVEHCIRQCVELLEAGVPGLHFYTFNRARAPIEILGALRGQQLLAS
>A0A3D9RNX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus wratislaviensis|TrEMBL
MTFDSVRGRASEGWVTRTPSIVDRIRSSSDGRVPFSVEFSPPRDEAAEARLWRAVREFER
LGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWEKHPDGVEYAEELVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSV
RRVLELSGSSLPAHLEKRLATAAGDGPEENRAAVREIGIDVATEMSERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSGVADPAPVTSARVS
>Q7V3C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4)|TrEMBL
MKSKLQQTLEKNSKVITAELMPPRGGDPVRSLKIAQLLRNKVHAVNITDGSRAIMRMCSL
AMSKLLLDNGIEPIMQISCRDRNKIALQSDILGANALGIKNILCITGDSVKAGDQQETKA
VHEFEAVRLLKQIQSFNQGIDPTFEQLPDKRTEIFSGAAVDPSCRNQRSLKSRTIKKKEA
GANFLQTQIVMDRKCLADFCNEISNPLEIPVIAGVFLLKSYKNALFINKFVPGANIPENV
LNRLKDAKNPLQEGILIASEQAQDFINIADGIHLMAVKSEHLIPEILEKAGLNLEC
>A0A563DEZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apibacter muscae|TrEMBL
MKVIEHIEQAQGKTLFSFEILPPKKGDNLQSIFSNIEPLMEFNPPFIDVTYHREEYEYKE
FSNGSIQKIVTRKRPGTVGICAAIQHRYGVDAVPHVICGGFDKEETENLLIDLNFLEIDN
ILVLRGDPIKSEGTYQAHPQGYSYANQLIHQVVDMNNGKYLHDEYANGATNFCIGVAGYP
EKHFESPNLDTDFYYLKKKIEAGADYIVTQLFYDNKKYFSFVERCREAGITIPIIPGIKP
ISIKKHLNILPKIFHIDIPQELVLAIEKCKNNKEANEIGIQWSIQQCKELIEYGVPVLHF
YSMGRSNNIQRIAKSIF
>D8JZJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalogenimonas lykanthroporepellens (strain ATCC BAA-1523 / JCM 15061 / BL-DC-9)|TrEMBL
MNVRDIYGQGKIVFSFELFPPRSEEASERLFATIKDLIPLEPACVSVTYGAGGSTRELTH
DLVVRIRQETGLTVISHLTCVGSSRDEIYRILERYQRSGIENIMALRGDPPKGQADFTPA
PDGFAHAAELVEFIREHFPDMGIGVAGYPEGHPQTPNRLTEIEYLKAKVDAGADYICTQL
FFDNRDFYDFRERCGLVGIRVPIVAGIAPVTSERQLRKMAEVAACTRFPAALLRAVSRAG
DDEGVREVGVHWATEQVRDLLDHGVAGIHFYTLNTSGATLQIYKALGISSSRQLG
>A0A7C6Z6F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfitobacterium dehalogenans|TrEMBL
MENRFKQSLLDPNTLSVTWELVPGRGAREKAQESALLAAEQAAKGGKVHALTITDNPGGN
PAILADYLGQEILKLGIEPLVHFTCKDKNRNQMESQLYALDRAEVRSLLVMTGDYTVSGF
KGRPKPVFDLDPTHALELITQMNQGLGIPGPKGISYHQTSDFFAGAAVSPFKGTEAEQMV
QYYKLKKKVASGAQFIVTQLGYDARKIHEVLQFMKLNDLNVPLVGNIYILPFGAAKIMNQ
NQLPGCVVTDKLLAEIDKERTAEDKGVSARLLRAAKMYALMKGMGFAGVHIGGHNIKYEQ
VEYVIEKGEELSKDWMALVPEFDYPMPNGFYYYEKDPKTGLNTTTPVNRKNLPLDAPVGV
AYSGMRMMHSMLFTPGKNFFPVMRKIYKGRKDNRKHGLEHLAKVITNDCKDCGDCAMFEL
AYLCPMSQCPKNQRNGACGGSYQGWCEVYPNQKQCIYVRAYARLKKYGEEGDLDSHHIPP
ANWDLYQTSSWSNFFLGRDHSGEILGIPTPEEEEKAKS
>A0A8B2WLI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDSGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTSVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSCEGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A6N7BBP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MKVIEHLDKAKNPLISFEIIPPKRGGNVRQLLHVLDDIVKYNPPFIDITSHAAEVMYEET
SDGGMQMKVKRKRPGTLGLCALIQNKYNIDAVPHVLCSGFTREETEDFLIELHYLGIDNV
LAVRGDDSAFKKPLKFGRSMNEYAVDLVKQINSLNKGKYIEDGLLDAEPMDVCVGVGGYP
EKHFEAPNLATDIKNTKEKVDAGASYIVTQMFYSNKFYFNYVDQCKREGISAPIIPGLKV
ITSKAQIKSIPKNFFIDIPQELAEEVEAAKPEHVMEVGVEWTKKQVEELLNKNVPAVHFY
VMQNSQPIKLLMNKLKL
>A0A7C7TEH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pelagibacter sp|TrEMBL
MNFSLEIGLSADLENLPPVKNVYITLLPGENYLKTTEKAGDLVKKGFNPVPHFPARSITD
EAQLKDYVSRCKDLGVKQALVIGGSQEQIGTFDSSIQILETGYFEGFKIGIAGHPEGSPD
ISDSNLEKAMKDKKPYADYIITQWLLDSQTIIDFVSKQSIPVHVGITGPMKISSLIKFAN
IVGAKNSINFLKSNFSKALDLLKPKDPNELIGKVKKFSDNFHIYTFGGLKETNKWLKENN
YV
>A0A6N3T640|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter indonesiensis|TrEMBL
MTDGQSNGLSEKHIDGLLLRNFEAPIPILSFEFVPARTDAMEQRLWHCIRRLAPLAPRFV
SVTYGAGGTTQTGTLSTVLRLKRETDLIPAAHLICVGATHEDVDDLARCYRDAGVNHIVA
LRGDPPAGAADYSPRPGGYAYASDLVAGLRRIADFDISVAAYPETHPAASSPDADLDNLK
RKLDAGATRAITQYFFDSEIYLRFLDRCLAAGITAPIIPGIMPVSNYEQIVRFSAVCGVT
VPAWLRHLFDGTAENPELRRIIASMVAVEQIRTLQTYGLNEFHVSTLNRSDLTYAIAHIL
GVRPTQTNASRNVTDLLETTEVPDDRETPADFDPTKGTQEGAPPFMLRTLFG
>A0A2D7UGF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pelagibacter sp|TrEMBL
MKFSLEIGPTADLSTLPALKDIYITMLPGGDYRETAQQAINLVKKGYNPIPHFPARSIES
DNQLKEYVDMCKDGGVKQVLVIGGGREPAGKFDSSYQLLETGYFEKMKIGIAGHPEGSPD
ISDSDLEKAMIDKKPYADYIVTQWLLDPQPIIDFISKQSIPVHVGITGPLKISSLIKFAN
IVGAKNSLNFLKSNFSKALDLLKPKDPNDLIGKLNSHTDYFHIYTFGGLKETNKWLMENK
YV
>A0A2D8RWA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvibaculum sp|TrEMBL
MTKTQKKEREERTRVSFEFFPPKTPEMEETLWKSIRRLEPLQPEFVSVTYGAGGSTRERT
HQTVKRIHDETSLEPVAHLTCVGASKAEVDDVIRAYWDAGIRNIVALRGDMPELGAPYQA
HPEGYQSTPELIEGIRKIADFNVIVSAYPEKHPESESIEADIELLRRKIDAGATRAITQF
VFDTDQHVRFLEKAHAAGIDVPIVPGIMPTTNFKGTKRMAARCGASIPKWLDDYYIGLDD
DLPTRKLIGAYVAAEQVNRLRSYGFDRFHFYTLNQADLTFAICHVLGLRPQTVPAEPEAV
>D3SE56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioalkalivibrio sp. (strain K90mix)|TrEMBL
MSDQKRVFSVEFFPPKDEAGAERLAKARKRLGALKPEFYSVTFGAGGSTRDRTLETVKDI
INKDGIPAAPHVSCISSTKGELHELLSTYRDIGVNRIVALRGDLPSGTKNSGGDFRYASE
LVEFVRAEFGDQFKIEVAAYPEFHPQAPNAEKDLENFKTKVDAGADAAITQYFYNVDAYE
AFMERVEKMGITIPIIVGIMPITNYTQIVRFSEMCGAEIPRYIRKRMEAYGDDKESIRKF
GIEIATRLTDDVLDKGAPGIHFYSMNQAGPTETIWKNLDLDNRR
>A0A0Q6RJV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Root1203|TrEMBL
MASNSDARRRIGISFEFFPPKSEEMEGQLWNTVSELQDWDPDFVSVTYGAGGTTKAPTLA
TVSRFLSGTPLATASHLTCVGATKEETHSVIDTFRDVGVKHFVALRGDAPGGVGAPYQPH
PGGYANAAELVAGLRELGDFEISVSAYPEKHPESLDTAADIEMLKRKADNGADRALTQFF
FDNDNFERYLEKVRAAGIRIPVVPGIMPIQNLTQLKRFAGACGTVIPSFLDERFAGFDDK
PEERAKVAAEVAAEQIEDLGRRGISDFHLYTMNRAPLVSAVLANLGLKRGQTKSAGAAA
>A0A352T9E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MKITDIASQKKLLVSMEVFPPKKQDALDSVVSAAQELTQLKPDFISITYGAGGTTKVNTL
EISQKILSFGTPALSHLTCIGNTKESISSAIEQMKLHNIQNVLALRGDIPQGSTAEASLS
PDLRHASDLIPLLKEAGFCVGAACYPEGHPESDDRLQDLENMKYKVDAGVDFLTTQMFFD
NNMLYSYLYRLQSAGIRVPVFAGIMPITNASQVSRMIKLSSAYVPAKLLAICDRFEKQPE
AMYQAGIAYVTDQIIDLISNGIKGIHIYTMNKPKVARDILNNISAIREAVNASQEK
>A0A3N6TR87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica cretica|TrEMBL
MKVIDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGSTA
DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK
FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYQSDLEYLK
KKVDAGADLIVTQLFFDTDMLLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCKTK
IPAEVMAALEPIQDNEEAVKAYGIHLGTEMCKKILAHGIKSLHLYTLNMEKSALSILMNL
GMIEESKISRSLPWRRPANVFRIKEDVRPIFWANRPKSYISRTKAWENFPQGRWGDSRSA
SYGALTDHQFSRPRARDKKLQQEWVVPLKSVEDIHEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLVKVNSKGFLTINSQPSVNAERSDSSTVGWGGPGGYVYQKAYLEFFCSKDKLD
ALVEICKALPSITYIAMNKGETWVSNTSQSDVNAVTWGVFPAKEIIQPTIVDPSSFNVWK
DEAFETWSRNWANLYPEAADPSRNLLEEVKNSYYLVSLVENDYINGNIFKVFSDL
>C1GJU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccidioides brasiliensis (strain Pb18)|TrEMBL
MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKARLERMSQALRPLFVNVTWGAGGST
VSKSLELAEMCQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTHAVDLVRYIRRMYGDYFCIGVAAYPEGHSDESHPEVQDPARDLPYL
VEKRKAGADFIMTQLIYDLEAYKRFEEMLRNHESGVFKTIPIIAGLMPIQSYHILTRTTK
LSHAKVPPDIMARVEEVKADDEAVKQIGIDILCEIVNGIKNLPCPGPRGLHFYTLNLEKA
VAFIVERCNLIPTSSEPSSDSDTELDSAVFIAPGMKNGVPLISKRRASSLNSQPHNRLIV
DHPASLSIGAPSSQTSTTHETQALGAGMLALNPPHQSTALQISEGMGALGREATWDDFPN
GRWGDARSPAFGEIDGYGPSLHVNANVARQLWGYPTSREDINKLFHCHVSGELHIVPWSE
GGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSDHPIFGWGPRGEGFVF
QKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGTTGLDDAVPDY
NGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFRIWDEWRRIFRRGSPTEQL
LDQLKKDAWLICVVGQKFGAGCGGKEASEAEKFLWRVLAGKEDTEANPTGLY
>A0A1I6RUN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces harbinensis|TrEMBL
MNDRAHTVRDLLAAGKRSYSFEFTPPRTEQGERTLWNAIRRVEAVGPTFVSVTYGAGGSS
RERTVRATERIATETTLTPVAHLTAVNHSVSELRNIIGQYADGGIRNMLALRGDPPGDPM
GEWVPHPRGVMYAAELVSLIKESGDFCVGVAAFPEMHPRSTDWETDIRHFINKCRAGADF
ALTQMFFNPEDYLRLRDRVAAAGCDVPIIPEIMPIANLRQIERFKQLSNSTFPEELENRL
RAVKDDPMAVRSVGIEFATELCARLMEEDIPGLHFVTLNTTLHSTATLDVYKNLGLHRAD
LEHG
>A0A2E1EDT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvibaculum sp|TrEMBL
MSKTPKKERNERTSVSFEFFPPKTPEMEETLWKSIRRLEPLQPEFVSVTYGAGGSTRERT
HATVKRIHDETSLEPVAHLTCVGASKAEVDDVIRAYWDAGIRHIVALRGDMPELGAPYKP
HPEGYQSTPELIEGIRKIADFDVIVSAYPEKHPESESLEADIELLKRKVEAGATRAITQF
VFDTDKHIRFLEQARKAGVEVPIVPGIMPTTNFKGTKRMAGRCGASIPKWLDDYYIGLDD
DLPTRKLIAAYVAAEQVNRLRSYGFDRFHFYTLNQADLTFAICHVLGLRPQSVPATPETV
>A0A0N0K623|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. AAP93|TrEMBL
MAAALIHPNWDKPPLGITDGFSLEMTAKDEASLREAAPLIPVDTPIAVTFLPGEDVAARV
KATVAVRELGFEPMPHFSARRITSEDDFEGYLKAVVEQAGVQRAFIVAGDPPEPVGPYFD
TSALIATGAFERSGIKAIGIGGHPDGHPNMTEQECWDVLVKKVAEIEARGMAPLIVTQFG
FDPDAFLAWLLKLRALGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTAVLRKYGISVTN
LLGSAGPDKLVDAFAAGLGPQHGRVRLHFYPFGGMVKTLEWIKGYNTKHGIAA
>A0A2G2A571|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pelagibacter sp|TrEMBL
MEYQSSLHKKLSXXEFVYTAETTPPDASNXXVLLTKIXXLKGIADAINXTDGPGAKVHMS
SLTAAIILAQNDIEPILQLTVRDRNRLALQGDLVGASALGVHNILCLTGDNPKNGDQPET
AAVNDINSLTLVATANMMRKDKKFPSGRIIDPPPKLFIGXAEMPAQGRPNPDKILNKIKT
GVDFFQTQYVFDATILKEYMKVLDHSGILEKASFIIGLGPFTSAKSAKWMNDNLXGVEVP
VEIIKRLKQAKDQKEESQKICLELIQVFREIKGVHGVHIMGHNKEQVIAEIIKESKKN
>A0A5U2UQ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADITNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A315XHH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon|TrEMBL
MSFSSKLRSGKFLITAEISPPKGTDTSPLLRDSALLEDIADAVNVTDNQRAVMRMSPLAA
CSILQGKGLETIMHITCRDRNRLALESDLIGAYSLGIRNVLVMTGDHTSKGDHEGAKPVY
DLDSVQLIGMIRKLDQGFDLCGNELNGRTDFCVGAVTNTILNDVGLIKFRKKIKMGAVFF
QTQAVFDVRGFAEFMEKTSEMRSRKVKIIAGIIPLRSESSAHFLNRVPGIRVPDDMIKQM
KDAKDPKLEGMKIAAGLIRELRTMCDGVHIMPIGNHENTRALLEMAGLL
>A0A8G0F5D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium asteroides|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLMPDFISVTYGTGRRSDRTATARISKTIH
TEYGIPAVAHLTARYADREVIDQALDMFDDAGVAAVLALRGDSVEGREPAGVFDHASDLA
AYIRFRRPNLPIYGACYPETHPEASSPEEDIEHLRIKVDAGVNHLISQLFYDNADFLDFL
DRARAAGILVPIEAGIMPITNEGQVRHMSRVCQARIPAAVESILERWGDDRASLREAGII
YASQQIADLVAHGVDGIHLYSMNHSGVTRRIWHNVRHLFRQAGTKEETVRSRK
>A0A7Y3NIC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionella sp|TrEMBL
MSKSHISFEFFPPQTPEGMEKLVNTHQQLAALGPEFFSVTFGAGGSTQERTLQSVAHIKA
QGSDVAPHLSCVGSTRESIRRLLQTYQAQGVRRIVALRGDLPSGMGSVGEFQYANELVEF
IRAETGDHFHIEVAAYPEVHPQAKSARDDLLNFKRKMGAGANSAITQYFYNADSYFYFVD
ECRKLGVTAPIVPGIMPVVKFSQLARFSDACGAEIPRWMRKTLEGYGDDNEAVQAFGLDA
VTALCEKLLAGGAPGLHFYTLNQAAPSLAIWQRLGLSK
>A0A2D7K853|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVVDYIKXSNKTIFSFEIIPPLKGKGIEDICKGIDPLMEFNPPFINVTYHREEYDYKKM
GNGLLKKVAVRKRPGTVGICAALMNKYKVDAIPHIICGGFTKEETESALIDLKFLGVDNI
LALRGDPMKNESSFVPTKGGNGFAIDXIKQIDEMNRGQYLYEETLNSPSNFCIGAAGYPE
KHFEAMNLNSDLKNLKLKVDAGAEFIVTQLFYDNNKYFDFVDKCREIGIKVPIIPGLKPI
TNLRHLTFIPKFFNTNFPEEFSNELEKCKSNEEVNQIGTQWAIEQSKELIKAGVPVLHFY
TMGKGEAVKNIASKIF
>A0A268TEP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. 11S02596-1|TrEMBL
MIEACVQKILNARFLSYEISPPKSPHIGETLLEELDEWGGFDALVCTDSPLAKCRQSPIL
ASLKLQNALKKPVICTLNMRDRNTIALQGDILGANALDIRMFLTLTGDPIKLGDQPNAKG
VFEGNSSLLVELIENFNQQKDLAGNPIKGTLKTIYPFGVLNAYANNLLSLKNKMRRKIKS
GVLALFTQPVYDIEIAKLLLEWCEEINAELGKKAQVVFGYFPIVRYKTAQFLYAKLPGVF
VPEIWLEKLENAHKISEIEEEKVGFELSKTLFENLKNLHPKIHFMNGNKIAMAKKIIG
>A0A1V5FCQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium ADurb.BinA305|TrEMBL
MKPEISIEFFPPTTAEGAEKLHATREKLAALEPAFFSVTYGAGGSTRERTFATVKEIAAA
GHEAAPHLSCVGSSRDSIREILQEYAAAGIRRIVALRGDLPSGAGAAGEFRYASELVEFI
RSETGDRFRIEVAAYPEWHPQAKSPKDDLAAFKRKVEAGADSAITQYFYNLDAYLNFVDA
VRRMGVDVPIVPGIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDSDAIRAFGLDVV
TRLCEKLLAAGAPGLHFYSMNMASPTTEICRRLGLTA
>A0A2S6VBL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroococcidiopsis sp. TS-821|TrEMBL
MIAVNKFQTLLNAGHFVVSAELTPPRHYKIKPLISKAEKIAAHVDVVHLNDNALSQARLS
NVVAAHLIQQLGIEPVVQLTLRHKNRIALQSDLLGLAALGIRNVMILGGYPCSIGSDPDA
KEVNDISAIEAIAAIHNFTTHGKMFNGDAIAPAPDFYIGTIAVPCTAPDKLEESMALLEA
KIARGARYIQLQATFDLASMQQWMAEVVKRGLHKRVHFIGAVFPFSSWKGLEFLQKIPGF
YIPNEVVERIRNSDPKSESLRVTIELIQGMQAIEGIRGIHLRLMGSSNCAEIVELAGLRQ
LAQCR
>A0A1E7XQG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus ferrivorans|TrEMBL
MAHSVEFFPPKNAAGEERLREAISALLPLGPEYASVTFGAGGSTRERTFVTVAMIRQDYD
LEAVPHLSCIGSTEAGIREILEDYQKQGIRRIVALRGDLPEGMENPGHFQHAADLVAFIR
HFGGFDVYVAGYPEIHPRATSARDDVAHLVTKVQAGADAIITQYFFNPDAYLQLRDDLQR
QGVDVPVVVGVMPITNFEQISRFSAMCGADIPQYVRRRMEAYADDPQSQYQLGIELLSRQ
CQLLLREGAPSLHFYTLNQAEATVAIWRNLSL
>A0A191WGS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces aureus|TrEMBL
MAPNATDPTGAAADRTPLSFELFPPRTDAAAIALGRTIDRLADVDPAFISVTFGAGGSTR
DRSLTVLRYILENTDIEPMAHLTCVGSSHVEANELVRRFLDAGIRSFLALRGDPPVGADP
DAPLGDLATASELVQLIHRVQQEREPFQQVAVAGNPGASRIRERSRTTRVAVAAFPSGHP
RSKDLSQDVDILLAKEVAGSNLAITQLFWEADEYLGFVELARAAGVTMPILPGIMPTTTP
ARLARLAELTGVRPPADFALALERESDAAAQTELGIDFVTRLAAEVLEGGAPGLHLYTYN
RHEAVLDVVDRLGIAAPRQLANERNFSR
>A0A2N0LIS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G5|TrEMBL
MKITEGCFEATGHTSIICDFSPPRSGDSAVVTQAQIDADFISVAYNPGRAVRTNSAMLAA
AIQQSGKDAVFTLATRDMNKLAVQSLLLGAQLLGLQNVVVVQGDLFGEQDQARVATVNDY
HSTGLISAIVQMNQGQDFKEAELRTPSDFCVGGTVDLGRGIEEEAQLAVRKVQAGAEFLI
TQPIFNVDHVARYRESYAYNAGKAGTLPIYFGLQILEQDGVLFSSVPESVRADLEGGRSG
VDIALELYQEFQKARLNNVYLMPPIKRGGARNYEAAKEFLTLINKI
>A0A1Z9PX72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacteraceae bacterium TMED237|TrEMBL
MKVIDHIKNSNDTQFSYEIIPPLRGKGIKIVLDMVESLKKFNPPFIDVTSHASTVSLNKH
GKKTKKKKRPGTISICGIIQNRFNIDTVAHLACNGFTKEETEDALIELSFLGIENILAIS
GDGNPKKVLNNGKTINSNSLELVHQIQNLKNGKYLTDIANSSSIEMCTGIGVYPENHFYS
NNFEKEISIIKQKIEAGAEYAVTQMFFDNQKYFDFLEKCRKENITIPIIPGIKILDKPKQ
IDSLEEIFHISLPDELKNEAKENIEYIDQIGANWAIRQSEELINAGVPVIHYYLMNDTSC
MLNILNYFYK
>A0A401YNT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Embleya hyalina|TrEMBL
MSLGAAATRISRTPAIRDLLADGTRSFSFEFMPPRTEAGTRTLWEAIRRVEALAPTFVSV
TYGAGGSSRGLTVDTTERIATETTLTPVGHLTAVGHSRAELRNIIGQYANAGVRNVLALR
GDPPGDPKGEWVAHPDGFTYAVELVELLRASGDFCVGIAAFPEMHPRSSDWDEDIRHFVA
KCRAGADYAITQMFFDVEDYLRLRDRVAAAGCDIPIIPEVMPVTSPTTLVRADELSGCSV
PADLSAAVEAVGDDRAAVRAIGVEYATRMSERLLAEGAPGLHFITLNRSTATTEIYQNLG
LDGDAGAARGAGSTEVG
>A0A5B9FH77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. WL3|TrEMBL
MAHIDENPLGPHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VTNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLSTPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMKKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDSVIARLEGAADQKMEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGILKGRQPWKREHARADDIAAQRMQEIGEDPVQDQQEMAGRAA
QSQTH
>A0A178L4D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas oryzihabitans|TrEMBL
MKPSLSFEFFPCKTEAGHEKLIATARQLAGHGPEFFSCTYGAGGSTRDGTYRTVRQLNDE
VGVPTAPHLSCVGDSKAKLRELLQQYQEAGINRIVALRGDLPSGMGLSGGGELRYASDLV
AFIREETGDHFHIEVAAYPETHPQARSFTDDVRNFVYKMEAGADRAVTQYFFNADCYFHF
VERVRKLGVEAPVIPGIMPITNYSKLARFSDACGAELPRWLRKQLEAYGDDTQSIQAFGE
EVMTALCERLLEGGAPGVHFYTLNQAEPCIAIWRNLGF
>A0A2S8HQP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas frederiksbergensis|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIQRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A157SEJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella trematum|TrEMBL
MTQSSSPAFSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTAETVRT
LANMGCDAAPHLSCIGASRDQLRDILAQYREAGVRRVVALRGDLPSGMGGDAGELRHAVE
LVRFIREETGDWFHIEVAAYPEMHPQAISPTADLNHFVAKVQAGADAAITQYFFNPDAYF
DFVERARARGVTIPIVPGIMPITNYSQLSRFSEMCGAELPRWIRLRLAEFGDDKASIRAF
GQDVVTDLCQNLLDNGAPGLHFYTLNQSEATMGIWKNLQR
>W4QAC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus hemicellulosilyticus JCM 9152|TrEMBL
MTFLNQLQSNVLIGDGAMGTQLYALGVDQCFEELNQTHPEMIVDLHEKYVNAGADMIQTN
SYAANAIKLEKYGLAKQVKDINYQSVKLAKQASHTDTYIFGTIGGIRRFQLEEVGLEDIR
NTFKEQAEILLESGVNGLLLETFYDLEEAKLAVELTRNLTSLPIVMNISLGEIGVLNGGI
PVTEAFKALYNNGADVVGLNCRMGPYHMLRSFETVPLPTEGYLAAYPNASLPDFRDGRVF
YQSNADYFQSMGKKFIEQGVRLLGGCCGTTPEHIAAFAKIKKEVAPITSKVVRPLHQMMV
KDQTPAKVDKPLPEIVKERHSVIVELDPPKKLSTEAFMQGAKALQDSGVDAITMADNSLA
SPRVDNLALGSMVKQHLSARPLVHITCRDRNLIGLQSHLMGLHALGMNDILAITGDPTKV
GDFPGATSVYDLTSFQLIQLIKQLNDGISFSGKELGEKSQFSVGAAFNPNVKYLDKAVKR
LEKKIESGADYFMTQPIYNETQIEALYHETKHLSHPIYVGIMPLTNSRNAEFLHNEVPGI
KLTDNIRSAMANCGEDRAASTQEGLSIAKSLIDTTLEYFNGIYLITPFLRYEMTVELKEY
IDQKAKSTRRV
>A0A6F7WAN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. AgN23|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRADLRNVIGQYADAGIRNMLALR
GDPPGDPTGEWVRHPDGLNYAVELVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATEVCARLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>A0A817R3F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood2|TrEMBL
MTLTHTEKNTASNHHDAHENGIGAENMSNSSHHFVDLKRSESEHACLAARGNSLQPVKYV
SLTEKIEKKIANNDRWYSLEFFPPRTTNGAVNLIGCLERMATGDPLFCDITWHTAGDPAG
TKETSTMMIANTMLNYCNIDTMLHITCYGAKKATMIEYLSKAKNFGIRNLLALGGDPPVG
ETWDPEKNDFRYASDLVKFIREHFGDYFVICVAGYPKGHPDSKNYEEDLGYLKEKVDCGA
DFIITQLFFQAETFLKFQSDCRAVGITCPILPGIFPIQAYASFKNIVRLTKLDVPDAIQT
HMESIKDNDQAIRDFGVQTCVDLCKALLDSGKVHGLHFYTLNREYATTEILKQLGFGFED
PPLRALPWKKTSRNHVRSKEDVRPIFWSTRPKSYIHRTSNWNEFPNGRWGISSAPSFGVL
TDYHLFYLKIDAAHNELLDEWGHELTSEQDVWKMFACYIGGEKNSSDKIVRHFPWKDEDM
SLETNLIHNELVEYNRKGILTINSQPAVNGKPSTDPIFGWGEKNGYIYQKAYLEFFTTAN
NIPALRAVLKDFPGVNYHFVNKSGEVNETNTDDEQPIALTWGVFPGKEIIQPTVVDPDEA
FNLWMERWGKLYEAGSRSYSIIEQISNTYFLVNLVDNDYPQGSCLWAVLDAMFEYQQKTN
QDTNS
>A0A7C7D3J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MAVELDPPTNPHIGNMIEGAKSLNTCGADIITIADCPLARARVDSSILAVKLKREANVDV
LPHMTCRDRNLNAIKASLLGLHMEGIRNILAVTGDAIPEAERIEIKGVFNFNSYMFIEFI
NELNHTVFNNNEIFIGGALNINSSNFDIELKRAETKIKKGAKFFLTQPVFGNEAIIELKK
IKNTLDTKILGGVLPIVSHRNAIFLNNEIPGIEIPENIIKQFEGKERDEAESLGIKIAVE
ICREILPYVDGLYIITPFNRWKMVCKIIEDIKTSQQFF
>A0A8B2P0U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acuticoccus sediminis|TrEMBL
MTRVSFEFFPPKSDAMEQTLWATIQKLEPLQPDFVSVTYGAGGSTRERTHRTVKRIVDET
NLKAAAHLTCVAASKEEVNAVIRDYWDAGVRHIVALRGDMPDGPGTPYKPHADGYANGAE
LTAGIKSIAPFEVSVSAYPECHPDSANWDADIDQLERKVDAGADRAITQFFFDNDLFEAY
RERVARRGIKVDIVPGIVPILSFKQIKRFAEMCGASIPDRLADRFEGLDDDAEQRMLVAA
AIAAEQVLDLQARGVDTFHFYTMNRAELVYALCRLIGINPVAQAAAAA
>A0A7X9AJY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKIIEMFNKKRPVLSFEIFPPRPDVPLDSIYAHLEQFEALRPDFISVTYGAGGSRKGRTL
EIASRIKKLHGIESMAHFTCVGHTREETDYMLKAMHSSGLENILALRGDPPADQPDFDFS
RGAYKHASELVEHIRKVNDFCIAAAAYAEGHVDSRRLSEDLAHLKEKVDTGVDFLITQLF
FDNRLFFDFIEKARAAGIKCPVSAGIMPIFKADQIKSIALKSGCSIPAKVVIMMDKYQND
PEDMRKAGIEYASLQIRELIDEGVDGIHLYTMNRPKSTREIMDSISLLR
>A0A7W0I0L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. CGMCC 1.16610|TrEMBL
MKLDLRAALQRDILTGDGAMGTYLYQMGFPVGISYEELNLLRPETVAEVHRRYFEAGARL
IETNTFSANREKLSKYGLEGDVEAINRAGVELARKVVGKDAYVVGAIGSIRAGKRKNVRT
ADVEESLREQISILLDSPVDGLMLETFYDLEELQLALRIIRSMSDLPVICQFANEGTGST
QDGVPLQEAFLRLRDEGADVIGFNCRVGPNGILRSMEKLTPLAGVPFSAFPNAGLPDYVD
GQYTYAATPQYFAESALRFADLGARIIGGCCGTTPEHIAAVAKALQDYVPAEPGTAVSAR
AVRVLEPAPAKPAPPAGKPSLLEIVKQRKTVIVELDPPRDLDIDKFMQGSRALQDAHVDA
ITMADNSLAVTRMSNLALGHLVQDKLGARPLIHIACRDRNMIGTQSHLMGLHALGIDHVL
AVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFVVGAAFNPNV
KHLDKAVQRLERKIEAGADYIMTQPVYDAGLIEQIYEATKHLHIPVFIGIAPLASGGNAE
YLHNEVPGIRLSDEVRARMSGLKGPEGRAMGVEIAKELLDAAMPYFNGIYLMTPFLAYEM
CVDLTKYVWEKSKRHDFHLYPLSK
>A0A1I2LJ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolymorpha cephalotaxi|TrEMBL
MPTPAFEVVCEVEPPARPDLAHVRRQIEVLGPVADAFLAPDNHLGRATISSVAVAHEIQR
AGGRGLACLNARDRNLLGLRRDLLTAAAYGVQRFVFVYGDKPTSGNRTGDLTVRAMLEEV
RRFAEEPDLRGGGFRAGVAAGPGPLPAWKRAADFVFAQVGFDVAEQVRWRETHGPDRPAY
AGVLVLSSEPMARRLAASIPDLDVPEELIRRVGQDRQAGVEAACDQVERIRDSGAFDGVH
LVTGVRFRPMAEALARRGFGGVRAGR
>A0A178U307|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parageobacillus thermoglucosidasius|TrEMBL
MGIQSDLMGLAALGVKNITILGGYPAKIGTEPNAKEVYDMETMELVRYVRRFIDEGKLFD
NTVMEEAPQMAIGVVENIVGKPVKELIDRLEAKIDAGANFVRTQLVFDIELLEEWMEEAR
RRGLHERAYIMASILPLRDADHVDAVLKIPGIAIPENIIKRIKEANSPDEGTKMVVELIH
KLRSIDGIRGIHIRPLGGMDRFVSKIVREAGLMNRKLGKVAGYVS
>J3ER54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM18|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGIQRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>N1QKG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerulina musiva (strain SO2202)|TrEMBL
MDKITDKIAALPSDATYFSLEFFPPKTQQGFANLNARLSRMAHSLRPLFVNVTWGAGGST
SAKSLALAEVTQRELGLTTCLHLTCTNMSRKLIDEALEQAKVLGIRNILALRGDPPRSDE
YRDDSLPDAGEDDSNKDFTWAVDLVRYIRKQYGDYFCVGVAGYPEGHSDQSHPEHQSIEH
DLPYLVEKTKAGADFIMTQLFYDVNAYQKYEKRLREHESGIFRTIPIIPGLMPVQSYQIF
RRTTKLSHASLPPEILRRFEAVKGDDEAVKRVGLDVLGEILDTMKHSEFPGPRGFHFYTL
NLEKVVAQILERNSLIPPSTPTIGANLGDEATTFDEVDDFVIIAEAKKKQQRRRSSMANS
GPRNRVIISSARESSTSSNRASSVYETFDHEAGVPREAINSRANTLAISEGEGSLGREAT
WDEFPNGRWGDARSPAYGQIDGYGVSLHVSVPEARRLWGEPKSVADISKSFARHLGGEID
TMPWSEESLQPETLTIKNELLQLINKGWWTVASQPAVNGVPSTDPVFGWGPKNGFVFQKP
FVEFFIPNDEWQKLQSKLFEHPQITYFAGNAKSDFASNNAESVNPVTWGTFAGKEIITPT
MIEAVSFRAWCEEAFGIWSEWQRIYKPGSESSRLLERIRKDYWLVSVIHHGYLEDGALWR
DLLEDGSSVE
>A0A419N8H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rahnella woolbedingensis|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRQIAQDYWDSGIRHIVALRGD
LPAGGGKPEMYATDLVHLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPKWMNSQFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEIAVPV
RA
>A0A6B1C458|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriia bacterium|TrEMBL
MKIRHMLAPGSPTVSFEFFPPKEEDGFGPLFETIDALRPLSPSYVSVTYGAGGSTRHKTV
ELVKRIKRDAGIEAMAHITCVGSTREHIADVLDSLEADGIENVLPLRGDPPRGSDRFEPV
PGGFRYANELVGFIRQRYSFCLGAACYPETHPEAASPEDDLANLKRKVDAGADFLITQLF
FDDDDFLRFRDRAVAAGISVPVLAGIMPVRSLSQTQRFATMCGARIPAELLARLEAVQAS
PAQVRAVGIDHATAQCRHLLAEGVAGLHFYTLNHSTATQAIYRRIRDQLGR
>A0A1W7M7E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. MD-1|TrEMBL
MATPLIHPNWDKAPDGITDGFSLEMTAKDEASLRDAAPLIPADTPIAVTFLPGEDVAARV
AATVAVRELGFEPMPHFSARRILSEDDFEGYLKAVVEQAGVERCFIVAGDPPEPQGPYFD
TSALIATGAFERAGIKAIGVGGHPEGHPNMTVAECWAVLEKKVAEIERRGMAPLIVTQFG
FDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVTN
LLGSAGPDKLVNAFAQGLGPEHGRVRLHFYPFGGLVKTLEWIHEYNRKHGI
>A0A109FDC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodotorula sp. JG-1b|TrEMBL
MVKISDKIRKAEREGRPWWSFEFFPPKTAEGWVNLYDRIERMTQLGPIFVDITWGAGGST
SEATTNFVKTAHSELGLETCMHLTCTNMPVDMVDKALKEAYDSGCRNILALRGDPPRGVK
EWKPTEGGFNHAIDLVKHIRKHYGDYFCIGVAGFPEGHPDSESQEAEIRHFKQKVDAGAD
IVFTQMFYDADVFIDWGRRLRAAGITIPIVPGIMPIQTFSAFKRRTDFAGTIVPQELWDL
LEPIKDDDAKVREAGTQYVANMCRKILNADLGIHGLHCYTMNLSRGTEMLLEEMQFVPTA
DRVKPLPWRVSLTQKRRTETTRPIFWSNRQRSYLVRTRDWDEFPNGRWGDASSPAFGDVD
ALLAALPIKPQDAIDLWGKPVSLGDIAALFARFCRGDLKRLPWSDQPAAKETSRIAEQLA
KVNELGFLTINSQPRVDGAKSEDPAFGWGPINGYVYQKAYLEVFCPPQHVEELLEILNDN
PSITYHAVNKQGDFRSNTAPGPNAVTWGVFPGAEVIQPTVVDSAAFQAWKDEAYELGSQW
AQLYQETSPETQKLIHSVFDEYHLVNIVYNDYRDPDEDAVFKPFFELASKKGLAAVNGH
>A0A5Q0SHP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas brassicacearum|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1J1JJH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktothrix agardhii|TrEMBL
MNRFRTACQTLDEFIVTAEVAPPKGADPSQMIEMVRLLKGRVHAVNITDGSRAVLGMSSL
AASIILIHHGVEPIYQLACRDRNRIGLQADLLGAQALGIRNVLALTGDPVKAGDHPDAKA
VFDLESVRLLQAIDKLNQGKDWNNKTLPDGATDLFPGAAVDPQSSSWSGLKSRFERKIEA
GAQFFQSQLITDFDRFDQFMTEIADSSKKPILAGIFLLKSAKNARFINKYVPGVCIPDSI
IDRLEQAKHPLEEGILIASEQVKIARELCHGVHIMAVKREDLIPKILDLSGIKPLF
>A0A0J6J4A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas deceptionensis|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDINNFVRKANAGADSAITQYFFNADSYFR
FVERVEAAGVMIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQAFG
EQVISEMCERLLVGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A6P1TMF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerocolumna sedimenticola|TrEMBL
MKIQEYLKQHKLIIDGAMGTYFARLENNENAVSEYANLADPAKILKIHRNYIDAGAVMIR
TNSFAANQQVLNIRPAQQAELITASYLLAKQAVAESGREVYIACDIGPIPEYSGRTEEDL
FEEYKLICDTFLKEKPEIILFETFSDFNYIKKLVPYIKEKAPETFIITNFLINKNGYTTK
GISARTLLEEIAGTKEIDAGGFNCGIGSGHMYHILKKLNFPANKFIVAAPNAGYPEQFQN
RMIFMDNEVYFEENMQRIIELGVDIIGGCCGTTPGYIKKITEKIDLQESNRGIRINLSVK
TEKLTELRSNDFFRLLESGKKVIAVELDPPFDAKDDQIITCAHKLREAGVDMITMADSPM
GRSRVDSILMSIKLMRETGMSVMPHVCCRDKNMIAMRSGLLGAYANGIRNVLIVTGDPIP
SENRQSTTGVFDYNSIQLMEYVKEMNREHFSEEPIYYGGALNYGRGPLEKIIERMEKKIE
AGARYFLTQPIFTDEDIERVKYIKSKINTKILCGIMPLVSYRNANFIKNEISGIHVPDWV
IERYTPEMTREEAEWTGAKIAGEIIERLNPFADGYYFMLPFNRVSLMDKIKIN
>A0A6N0BL01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax sp. BAB1|TrEMBL
MSLQQLPLSIEFFPPKTPEGVEKLRVVRQQLKALKPEFCSVTYGAGGSTQEGTFAAVREI
LAEGMDAASHISCIGATQATMRENLATLKAMGVKRLVTLRGDLPSGYGAGGEFQYASDLV
AFIRAETGDHFHIEVAAYPEIHPQAKSPAADLQAFVTKVKAGADSAITQYFYNADAYFRF
VEEADALGVTVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIKAFGL
DVVTELCEQLRAGGAPALHFYSMNQSVATLEICKRLGL
>F9UND4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHADHPVYILGTIGGLAGDTDATVQR
ATPATIAASVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFVGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A1I4KBZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium pseudosasicola|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTDEMEKILWSSIERLAPLQPKFVSVTYGAGGSTR
ERTHNTVARMIRETTLKPAAHLTCVDASRAEIDAVVQAYWDVGVRHIVALRGDPADGVGH
AYKPHPEGYATTAELVEGIKRIGDFKVSVSAYPEKHPEAASLEADIDALKAKVDAGADQA
ITQFFFENEVYLRYLEKVRAAGITIPIIPGILTVQNFKQAANFARRTGASVPYWLAARFE
GLDNDVETRRLVAAAVAAEQVLDLVDEGVQDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AEKAAA
>A0A291BIF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus brevis X23|TrEMBL
MTTRKKDLRAYLKDHLLVGDGAMATQLHGLGVPVGVSFEELCLSNPRLVHEVHTSYYQAG
ARFLETNTYSANRDALSRYGLEHKVARINRLAVAIAREAAQDDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGVDGLILETFVDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYALTDAFSELKAAGADVIGLNCRLGPAELLRSFENTVIPEDALLSVFPNAGRLG
MTDGEYAFKSSPEYFGQSALRLREQGVRLIGGCCGTTPAHVKAIADALESLEPQARVNPT
IVAGDRPSISVQNTREREKPSIVERVKTATTIIVEFDPPRDLDADQFLHGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKSRHGIDPLLHIACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMDAAVARLEKKVEAGADYIMTQPVYDAESIRNVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSTEALERMKKVQGEAARQEGIAIAKELVDTAVRYFNGIYLITPFNYYE
MAAELIQYTRQQSSLVKLAQT
>A0A2S6SUG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha5_Bin5|TrEMBL
MKNDQNLSLAKKLLKSYSIETTPNVYNKYGKFSDIVNKTNSIYITYLPDEESIKVIDCAK
KLKIEGFDVIPHLPARTIKNNIELENYIKQLAEVCGCSKILIVGGGGNQKGEISSTMDVL
ETDLLSKYNFTEVGVAGHPEGSPDINKDELKNAIIQKNKFAQKADFKIYLTTQFFFQAKS
LIDWEVELNKLNNNLEIHAGIPGPASIKTLFFYAKSCGIGNSLRFISKQAMNITKLANSK
TPDKLIYDLASYKNKFTNSKLKKLHFYAFGGIKKTSDWLNSLQKSDIIYKNNQFISNI
>A0A1Q6D5I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIHSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKISEPVLAMIERWGSNPEVLQDTGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A0S2ENW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas sp. AU20|TrEMBL
MIQRRSQRAPFRVSFEFFPPKTEAMETGLWTSIQRLAPLSPDFVSVTYGAGGSTRERTHH
TVKRLLAETDLKPAAHLTCVDATREEVDEVVRQYRETGVKHFVALRGDGKAGAGGAYESH
PGGYRNAVDLAAGIKAIDPEIEISVSAYPEKHPESSDFATDIDLLKRKVDNGATRAITQF
FFDNDVFERYVERVRRAGIYIPIVPGIVPIHDFTKVARFSAATGASIPLWLAERFEGLEK
DAHTHSHVAAAVCAEQVLDLAERGIEDFHFYTMNRADLVYSICHILGLRPKNAGGGDDKV
TEVEQAA
>A0A3Q7IQV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solanum lycopersicum|TrEMBL
MKVIEKIQEAAKTDKVIFSFEFFPPKTDDGVENLFERMERMVAHGPSFCDITWGAGGSTA
DLTLEIVNRMQNMVCVESMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGIATKEIYENDLAYLK
KKVDAGADVIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTK
IPDEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALAILMNL
GLIEESKISRPLPWRRPANIFRVKEDVRPIFWANRPKSYISRTTGWDEYPHGRWSNAQNP
SYGALTDYQFMRARSRDKKLQEEWAAALNSVEDIYEKFKDYCLGKLRSCPWSELDGLQPE
TKIINEKLGQVNTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSQEKLN
ALVEKCKSFPYLTYMAVNKEGNWISNVNQTDINAVTWGVFPAKEIIQPTVVDPASFMIWK
DEAFEIWSRGWAQLYPETDPSRKLLEQVQNSYFLVSLVDNDYINGDLFSIFKDI
>A0A5J6NUJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrio sp. KY-YJ-3|TrEMBL
MNDSQPRLSFEFFPPKTPEGKEKLIKVRDQLNAFAPDFFSVTYGAGGSTRDNTKGLITQF
KSDGIAVAPHLSFGGDDETTIKTLIQEYKDAGVDRIVALRGDMPSGVGGAYQLVYANELV
AFIRKHYGEHFHLEVAAYPEIHPQAKSYSDDVGYLKGKFDAGANSAITQYFFNPDSYFYF
VDQCQKAGITQPIYPGIMPIINYKNLTRFSDTCGAEIPRWLRKALENYGDDEASLRAFGI
ELVTDLCDTLLENDAPGLHFYTMNQTEPTAEIVRNLGLIPNDE
>A0A2K1PX82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter silvestris|TrEMBL
MTPLSFEFYPPKTDEQRAQLDRSVQKLKPHSPEFMSVTFGAGGSTLSHTPETVQRLRGEH
GVDGVPHLTCVGGSREEIRSLLKLYRALGCSRIIALRGDMPSGMIGQGDLRYANELVELI
RAEHGDHFQVTVAAYPETHPQADDAHVDLANFERKVKAGAHNAITQYFYNSDAYFHFIDD
VRKRGIDIPIIPGIMPISNFTQLRRFSEACGAEIPRWIGQRMRAHGDDAEAIREFAADLV
ATLCRRLVDGGAPALHFYTLNMARPTQAILQRLA
>E1SN50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrimonas balearica (strain DSM 9799 / CCM 4581 / KCTC 23876 / PAT)|TrEMBL
MGFHHAQQVEALNERLSSLRDIQVSFEFFPPSSAEMETTLWHSIERLAPLKPRFVSVTYG
ANSGVRDRTHKVIERIHNETQLQAAPHLTLVDASDEELRTLAQQYWDQGVRHIVALRGDV
PQGQPNPNRYASDLVSLLRDVGDFEISVAAYPECHPEALSAQADLINLKRKVDAGATRAI
TQFFFDIEAYLRFRDRCAAAGIDAEIVPGILPVTNYQQLLKFADFAKIRVPNWLHHMFDG
LDDDPATRKLVGANVAIEMAKVLAKEGVEEFHFYTLNRAELSYAICHALGVRPGLEG
>A0A4R4XZI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. KC06|TrEMBL
MGFEVVCEVEPPMRPDLTRVRHQIGVLSPVADSFLIPDNHIGRATVSSVAVAHEVQAMGA
RGIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVYGDKPSAGGRTSELTVRAMMDETRAA
GDDAAFAGCGPFQVGVTSGLRKVPEWKKAADFMFVQVSYSIENLLRWRESVEVDGPVYAG
VMVLASGGMARNLASSIPDIDIPAELVEAVERDRSAGVAAACEQVLAVRESGAFDGVHLV
PVSRYREVAAVLERELR
>A0A0S3TWU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. NIES-3755|TrEMBL
MTYPQFSNPLGHAPLSALRTAAKRGEFLVTAEVAPPKGTDPTHMLQMAHLLKGRVHGVNI
TDGSRAVMRMSSLVSAALLLQQGIEPIYQVACRDRNAIGLQADLLGAHALGIRNVLALTG
DPVKAGDHPEAKAVFELESVRLLQMIAKLNGGNDWNDKTLTDGETDLFVGAAVDPQCGSW
SGLQKRFERKVAAGAQFFQSQLITDFERLDKFMTQIAIDHGKPILAGIFLLKSAKNARFI
NRAVPGVNIPEHIIDRLEQAADPLQEGVRIAAEQVKFAKELCQGVHMMAVKREDLIPEIL
DLAGIKEIDRTLVEVGKA
>A0A0Q7AVP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobacter sp. Root404|TrEMBL
MTAAREVPISFEFFPPNTPIGDEKLKGVVQELGALAPEFFSVTYGAGGSTREKTLATVTA
IAAAGFEAAPHLSCVGSTRAGLTEILATYRAQNIRRIVALRGDMPSGTHLGGDFRHAADL
VAFIRETQGPDWHIEVAAYPEYHPEQRYAARDLAHYVTKVKAGANSAITQFFFNADAYFH
FVDATTKLGATAPVVPGIMPFHNFAKIAQFAARDGIEIPRWIALKMEGYMDDTASIRAFG
IDVVTELCERLIAGGAPGLHFYTMNQAPVTVEICRRLSAR
>A0A368SD36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Setaria italica|TrEMBL
MKVIEKIQQAAADGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLDIANRMQNMVCVESMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATPEAYNNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVDDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTK
IPAEITDALEPIKENEEAVKEYGVHLGTEMCKKILASGIKTLHLYTLNMEKSAIEILKRL
GLIEEFKVSRPLPWRPPTNVFRVKEDVRPIFWANRPKSYIRRTLGWDQYPHGRWGDSRNP
SYGALTDHQLQEEWAVPLKSVEDISERFTNFCRGKLTSSPWSELDGLQPETKIIDDQLVK
INQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLVEKIKAFP
SLTFIAVNKYGVSASNIPANAVNAVTWGVFPGKEIIQPTVVDSGSFMVWKDEAFEIWTAG
WACLFPEEDSSSKELLKKVQDNYYLVSLVDNDYIHGDLFAAFKEI
>A0A2H5ZA51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR29|TrEMBL
MPFAVDLQTGAFPVSLEITPPKRMLRGILLRRARLLGECVRTINVIQRPDRLPSLDASIE
LLRHGFEPVWHLVTRGREEEDIRADIERAAAAGVRHALCLLGDHAVEREPARPLRIRETI
ALMRQLAPEITVGATLNQYAPSSDAVLRNLLPKVEAGAAYVQTQPVVELEAFLRLAERVR
REVPDLRIVPMVMPIVAPETAQRVGARLGFSASESILSRLAAGDGWRLFQDTVAQLRESG
LADGVAVMTFEMDPAPEVGDRIREALVGAGALSC
>A0A2E6Y9L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stappia sp|TrEMBL
MSSSDKFRRFELGNDSASRVNVSFEFFPPKTEKMEASLWNAVKRLEPLNPAFVSVTYGAG
GSTRERTHRTVERMIRETSLRPAAHLTCVGASREEIDEVIRSYHELGVRHIVALRGDPQE
GIGAIYKPHPQGYAYAGDLVAGIHRISPDMEVSVSAYPERHPESADWQTEIDNLKRKIDA
GATRAITQYFFDNDLFETFLEKVRAAGITIPVVPGILPIVNFETTMVFSAKCGTSIPHWL
AHRFSGLDEDAETRKLVASAVACEQVLDLVDRGVTDFHFYTMNRSELTLAICRMLGLVPA
PVEQQAA
>A0A673TTU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Suricata suricatta|TrEMBL
MDHPTPKVLLARPRGPSLQMWALEAGSGRFSVPPSISRNSVMVNEPRGDGGPTPRLEGSS
SGSESSKDSSRCSTPGLDPECHDRLREKMRRRMESGDKWFSLEFFPPRTAQGAANLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCCQSREQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEDGGFSYAADLVRHIRSEFGDYFDVCVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREMATTEVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMWGEELTSEESVFEVFACYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPGTEQETETL
>A0A812AF45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MEDCHQRVGDNPGAKGVFDLDCVQLISIMKKIEHSLVGTRINPFAHPLELHLVNLSKKIN
AGVDFIQTMPVFDLERFKEFISLIKGENLYLLAGVRPIKSWQALQSMSQMVIPENIVQRI
KNTPENKQAEEGIKICVEIIKALKQIKGVNGIHIFAHDWEEAVPILVRQANLK
>A0A1Q6S8N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:65_45_313|TrEMBL
MGNTKHTKEQIRERIQQKKLLFDGAFGTYYGGKYDTKQLPELANLEAPERVKEIHTEYLE
AGAQILRTNTFAANSFCMDMSKEQIEETLRSGVRLAREAVAAWRARTGETKEVYIAGDIG
QIPGDALAQKDTLCREYEEICRIFLEEGVDFFVFETFSEMEELLPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGAIKEIDAVGFNCGVGPSHMYRILQTLYKPADKFLTALP
NAGYPQMVTGRMIFTGDNREYFVDRMQQMIALGVDMAGGCCGTTPEYISDLAGKLDFTQY
PQTQEKAEPEKKQAATEDHSFYHKKEAEGGKKLIAVELAPPAGIDDEKLMDAAHLLQRSG
VDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGIH
NFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFARAPVSYGGAINQGRRNLE
VEIGRVKKKMAAGATFFLTQPISTKESADRVRRIKEETGARILCGIMPFVSLKNATFMKN
EMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVIAMTEDFADGYYFSFPFNRVTMLEK
ILD
>A0A7Y7EE17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagia bacterium|TrEMBL
MKVTEHIRNAKGKTLFSFEILPPVKGESVQNIFAAIDPLMEFKPPFIDVTYHREEYMYKK
RENGLLERVTTRKRPGTVGICAAIMNKYHVDAVPHIICGGFNKEETENALIDLDFLGVDN
VLVLRGDAIKSEGRFVPDPEGHSYASELLEQVMELNQGKYIHEEVTRNKTNFCVGVAGYP
EKHFEAPSLRSDMKYLKQKIDGGAEYIVTQMFFDNKKYFEFVDKCRENGVNVPIVPGLKP
ITTLNHMSILPSVFHVDLPDDLVDELDKCKDNAAVKEVGIEWAIQQSKELMEAGVPVLHY
YTMSKSHVVKRIAEALF
>A0A6L3UWI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus casei|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNVALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDLEPVAHLPAAQLTRAQVDVELHGFQEAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQRGDFNVVAACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYRFRERTELAGIHVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIATATKTIRNT
>D4S201|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio crossotus DSM 2876|TrEMBL
MKIIDLLKSDKVTVSFEVFPPKSEANYESIYNAAMNVAALKPAYMSVTYGAGGSTSKSTL
DIAGDIQKRYDVCTIAHLTCAGADKDDIHKSLDGMKTKGIENILALRGDIPKDYDGDPFA
HYRYASELISEIKEYAGDSFCIGGACYPEGHVDAANKKEDIGNLKKKIEAGCEFLTTQMF
FDNNIYYNFLYRIREQGIVVPVVPGIMPITRATQVANALKLSGSNMPERFRNLVDHFGTN
PAAMQQAGIAYATDQIIDLIANGINHIHVYSMNKPEVAAGIQKNLSEIIK
>A0A1Q5T8D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium subrubescens|TrEMBL
MHIREKLASKEAAGEPSISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGHLS
DLTCEMVGVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEATENGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNSDVDLLIDHLKEKVDAGSTF
VITQMFYDVDLFIEWVKKCRAKGITVPIIPGIMPIQQYASFIRRSNWTKARVPPEWMEAL
EPVKNDDAAVREIGKRLIADMCRKLMAFGLNHLHFYTMNLAQATKLVLEELGLAPSEEAP
IQRALPWRPSLALGRRTEDVRPVFWRNRKSSYVARTQTWDEYPNGRWTDSRSPAFGEVDA
YGVRLKGTNEQNIKLWGEPKSIKDLSEIFIRFLEGKLDRLPWSDSPISAEALDIKDHLVN
LNQRGFLTINSQPAVNGVKSSHPIYGWGPKNGFVYQKAYLELLVPPSLIDELTARIEKND
DLTYHAIRKNGELRTNTHDSPNALTWGIFAGREIIQPTIVETISFLAWKDEAYRLGEDWS
KCHDSASPSRKLIQQVMDDWYLVNIVDNDFHRNNAVFELFNDLEVKDLNVELLPGKPETN
GSAEQNGAATKN
>A0A2T6N3J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium symbiont of Ctena orbiculata|TrEMBL
MQRDNQQKTFSFELFPPKTERGQENLQKAVAELSARQPAFFSVTYGAGGSTRQRTFDTVE
WLIGERITTAPHLSCIGASREEILEILAHYKALGISRLVALRGDLPSGAGMGELSDLGHA
NQLVELIQESYPKQFHIEVAAYPEFHPQASSAQQDLNYFKLKVDAGADSAITQYFYNADA
YFRFLDSCQKLQINIPIVPGIMPITNYTQLARFSDACGAELPRWLRKRLEGFGEDLEAIR
SYGADIVVGLCDRLLEGGAPGLHFYTMNQAKPTLDIWRALSL
>N1J4Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blumeria graminis f. sp. hordei (strain DH14)|TrEMBL
MHIKDKLRQAESSGHPTFSFEFFPPKTTQGVQNLYDRMDRMHGLGPSFIDITWGAGGNIA
QLTVEMVSVAQSQYGLETCMHLTCTDMGLEKVDKALKDAYKAGCTNILALRGDPPREQEK
WTATDGGFHYAKDLVKHIRATYGDHFDIGVAGYPEGCDDQDDPELLLDHLKEKVEAGGTF
IVTQMFYDVENFLEWVGKVRAKGINVPIIPGIMPINTYASFLRRCNHMGCKIPPKWATAL
EGIKNDDAAVRSIGTGLVAEMCRKILASGLIHHLHFYTMNLAQATRMVLDQLGLTPSEER
PLKQALPWRQSLSLGRRDEDVRPIFWKNRNKSYVTRTQDWDEFPNGRWGDSRSPAFGELD
AYGIGLKGSNQQNRKLWGEPECIKDVAEIFVKYLDGKIESLPWSEAPISSEANKIKKELE
DLNRRGFLTINSQPAINGIKSSDSTYGWGPPNGYVYQKAYLELLVPAYLIDELLTRVSKD
AYLTYYAVNKAGDLKTNSTHEGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGID
WAQCHSATSPSRRLIEKIMDTWYLVNIVNNDIFENNKLFELFEGLQVNDIDKPLESPKIM
NGNSAHQNGHEPYENGKVTIENGNH
>A0A2U8WG55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium terrae|TrEMBL
MYATSFRPSRESCRPIRVSFEFFPPKTPEMETTLWSSIERLAPLNPSFVSVTYGAGGSTR
ERTHNTVSRLVRETDLKPAAHLTCVAATKAEVDDVVRAYHEAGVRHIVALRGDPAEGVGT
AYSAHQGGYERSCDLVAGIKRIGDFEVSVSAYPERHPEAGSLDQDLDALKAKVDCGADRA
ITQFFFDNDLFFRYLDRVQSRGIDIPIIPGILPVQNFKQAANFARRTGASVPDWLAARFE
GLEDDVATRKLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRAAPVAAE
KAAA
>A0A2N2K431|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-15|TrEMBL
MTEKETGFQARLRSREQVLVVEVAPPKGGDPIPLRSAAKRYQGKVHAISVSDNRHGICMA
SIAAGAILASEGMEPIVHVLTRDRNRIALIADCLGAQALGVRNILCTSGTHQTLPGCSQA
RNVFDMDSTQLIEAIAHLGNNGSMFFGERFEPAGPFCLGAVAAPFADPAELQLIRLAKKV
NAGAEFLITQPVYDLDRFRTWWGQVTKRSIHEKSAILASIQPLLHAGSAKAYAESRPTPG
VPRSLLDRLSSAGNAEAERAAGIDIAVETIKQVSALKGLAGFQICADGDEGAVLEILERS
GLEVR
>B0NKZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides stercoris ATCC 43183|TrEMBL
MQDCAGFCQLDKDNGKEMRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDP
KYINITTHRSEYVYKDLGNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSRE
DTEYVLLDLQFLNITDLLVLRGDKAKHESVFTPEKNGYHHAVELQEQINQFNKGIFVDGS
EMKVTNTPFSYGVACYPEKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVE
RARKAGVTIPIIPGIKPFKKLSQLSMIPKTFKVDLPEELTNEILKCKNDAEAQQVGIEWC
VQQCKELMKHHIPSIHFYSIGAVDSIKEVAKQIY
>A0A1K1X1U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. NFACC47-1|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRSLLTQYKAAGIERIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLLNFVRKANAGANSAITQYFFNADSYFY
FVERVRRLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2R3Z5J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gramella fulva|TrEMBL
MKVTEHIQKANGKTLFSFEIIPPKKGKNIQELYDNIDPLMEFRPPFIDVTTSREEFVYVE
RDGLFDRQITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFTKQETEYLLVDCQYLEIENV
MALRGDAMSHQKYFEPSEGGHNFACELVKQIKDLNTGRYLHDVIETDYNSEFCIGVAGYP
EKHMEAPSLKSDLKRLKEKVDSGADYIVTQMFFDNQKFFEFVKAAREMGIEVPIIPGIKP
IAVKKHLQLLPQVFKIDLPEELISEVEKCKSNKEVRQLGIEWCIQQSKELMDFGVPVLHY
YSMGKSSNIEQIASAVF
>F0JGR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio mercurii|TrEMBL
MRVCDLIDGKSPFISMEFFPPKEREAWPAFFEVVDKLKVLDPLFASVTYGAGGGTQDNTL
EIATRMKRDHGIEPVTHLTSVGASAAKLDGFLESLIEAGIDNVLALRGDPPRGVVDFDFN
AQEFKHASDLIEYICARYPSLCVGGAAYPEPHCESPSIRSDLDMVHLKVRKGAKFLVTQL
FFDNRMYFDYVERLKLMGSDVPVIPGILPIMSLKSAKFILGLCGAAIPGKFLSALEKAHE
EGGDDAVYRLGIDYATKQARELIEGGAPGVHLYTLNRAEAVLEIGKNLNI
>A0A2A7MMM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium neonatale|TrEMBL
MINEYLKNRVLVSDGAMGTYYSEISGNDISYCEFANLNDKNTIKKIHSKYIEAGAKLIRT
NTFSANIYDLSVTHKALKEIIHSGIDIAKEATYNKDIFIGGSIGPIRKENSLDEFDEEIL
DEYKFIVDCFLEKKIDIFIFETFSNYTYLDEISKYIKEKNNETFILTSFAFKPDGFTRDG
LSVSKVLSYLENINEIDGYGFNCGSGPSHLCEIVKKSAINNKIIAVLPNAGFPEIIHERT
VYPNNPVYFAKKVSELKNFGVSILGGCCGTNPSYVKELSSYISASKLGDNIKTNVVITNE
HTIKLKKNKFKQKLDDGEFVIAIELSPPSDTEISKVIEGARLCKENNVDLVTVPDSPMSR
VRADSVIMASKIQREIGIDAMPHVCCRDKNTNAIRSSLIGSHIENIRNVLAITGDPVSDA
SKVQTKSVFNLNSFKLIELINDMNTEVFKEDGMLIGGALNLNVFNKEVEFNRMMKKIEKG
ADFFLTQPIYDDEAIEFLKVIKQRVDVKILAGVLPIVSYRNAMFLHNELPGVTIPEKYIN
MFSEDMTKEEGQSVGTEIAVDIVKKLKEVSDGLYFIAPFHRVSMLIDIIKQIRD
>A0A8H9J085|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis bartoniae|TrEMBL
MKSVVERLRGEGPVFSVEFFPPRDAADEAVLWRSIRELEALDPAYMSITYGAGGSSRDGT
IRNIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGEWV
PHPEGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSPDLASDTKYLVRKFRAGAQFAIAQ
LFFEPEDFLRLRDRVAAAGCDAMLIPGVMPLTTPRTLKTTIKLSGASCPQWLLDRLGPLE
SDPKAFRAEGLDVVTELCERLIAEGVPDLHFYTFNRSKATREVVQRLGLVPVRA
>A0A7J5A9T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium luteum|TrEMBL
MKVTKHIENAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVN
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKEGGNNYATDLVTQIYQLNQGKYLHEVLDVDNKADFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNTKFFEFVKKAREIGINVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLINAVDQCKNNAAIKEVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRKIAGKVF
>A0A8H3YVI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Venturia inaequalis|TrEMBL
MGIPKPMRLLAFISLGIFFYVCFLMFSSPLELQVPGKGKIEKMTKDPNLEPTGEPPEPLR
RVVGSNYAPNNPNSERINATLLALVRNNELRDMLQSMRDLERTWNHKFNYPWLFLNDEPF
TEEFKTAIRGATKAEVKFELVPKDHWETPSWINDDLYQESVKVLKEQGVQYMDKKSYHNM
CRWNSGMFYKHPALLEMQYYWRVEPNVHFFCDVDYDVFRYMQDHNKTYGFTVNLYDNPES
VAGLWPSTQQFIADHPEYVHPNSAIKWLQDDTMRRENYVKANGYSTCHFWSNFEIGDMSF
WRSKAYEEYFQHLDRAGGFFYERWGDAPVHSIGLGLFEDQNKIHWFRDIGYQHIPFFNCP
NSPKCSGCVTGRFTDGEQWLNKDDCRPAWFKYVGMASTLNMEKITDKLAALPEDGTYFSL
EFFPPKTTAGFANLQARLERMSRALRPFFVNVTWGAGGSTATKSLELAELVQRQLGLTTC
LHLTCTNMNKSLIDSALERAKAIGVRNILALRGDPPRNEEYFNKEDLDKESTEFVWAVDL
VKYIRKQYGDYFCIGVAAYPEGHSDQSHPDDQNPKHDLPYLIEKTKAGADFLMTQLFFDV
KAYEEFEDMLRNDPSGVFKTIPIVPGLMPIQSYQILRRTTKLSHARLPPDILERLDVVKG
DDEAVKAVGVDIISEIIQELQARPHVGPRGFHFYTLNLEKAVSQIVERCHLIRDLSAMDD
DDDDDSALEISDDVPDSNGQQRRSRLSSVHSDPRNKVIADRPSGHLNPEYETMEKEAGLP
IEGATRATTLLISEGEGSLGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVSAPQALK
LWGYPVTIDDVSSIFRRHIAGDLEAIPWSEDGLNPETATIREELLKLNAKGWWSVASQPA
VNGIKSADEVFGWGPRNGFVFQKPFVEIFIPAADWTGLKRKFEAYPEEITFFAANVAGDF
ESTDTKSVNPVTWGTFPGKEIVTPTIIEAVSFRAWAEEAFSIWREWQHIYPPRSATAKLL
GGIREEYWLVNIIHHAFIEQDGLWKLLLD
>A0A411Z7N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tabrizicola alkalilacus|TrEMBL
MATPRISFEFFPPQTLDASFRLWETVQALAPMQPEFVSVTYGAGGTTRKLTHEAVTAIGK
NYGLNVAAHLTCVDATRAETMEIAAAYAEAGVTEIVALRGDAPKGAERFTAHPDGFASSV
ELIEALAATGKFKLRVGAYPEPHPDAADSLADVRWLKRKIDAGATSAITQFFFDADTFFR
FRDLCVKEGITAPIIPGILPITSWAGAKKFALRCGSDVPARLDEAFTTAARDGREELYAL
AHCTQLCDNLLQGGVEDLHFYTLNRPHLTREVVRALGIQPELVPELVLEKVA
>A0A013VSL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. Ant17|TrEMBL
MTLPSIHPNWDLPPKGMTDGYSLEITAKDIDALREAAPTMAADTPVAVTFLPGESLEARI
AAAKLVRSLGFEPMPHFSARRLESGDDFETYLAAVVREAGVQRCFVIAGDPPEAAGPYSD
SMALIRTGAFERAGIKAIGVGGHPEGHPNMTPDQCFAVLTEKCAEIEQRGMAPLIVTQFS
FDAAPVLSWLADLRQRGIDAPVRIGIPGPAGIKTLMRFAARCGVGASASVLTKYGISITK
LIGTAGPDKLVDALASGLGDQHGKVRLHFYPFGGLTKTVEWINDYTARH
>A0A356UCJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas sp|TrEMBL
VVNKKQIDRMVSLCGVKLPKKFVTMMERYENNPLAMRDAGIAYAVD
>A0A0C3QK59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tulasnella calospora MUT 4182|TrEMBL
MKLTEKLSQRDGQTPFFTFEFFPPRTDQGFTNLLARISRLTPLDPLAISVTWGAGGSTRE
RTMDLAGMSQARFGVDMIMHLTCTNMEQGMVEEALREAKDREITNLLALRGDPPRGSEFW
LPIDPRFTHAIDLVKYIKSSPEFADFFCVGVAGYPDGHPDGLPLDAQMQHLKAKVDAGAD
YIITQLFYDVNNFKDWVRRVRNAGITVPIIPGVMPIQNHTSFLRMAKLCGAKIPPEVTAA
LESIRNDDQKVKDYGVELAITIVKNITEDAALGIRGVHFCTLNLEKSVRRILDALGWTHE
SHRPRNQIIDSAPAEPHLPSQVAISPEHASKVAVSALSNPPASLSVPQSSEQEEGSTATD
LAGVSSTWDEFPNGRFGDPSSPAYGVGSGDQWDPGAGGLGVSRAEAITQWGTPTSIEDLN
AMFTRHLNSDPRTPTTPFSPDALLAESRMILPQLLEMTLKGWWTVGSQPAVDSAPSNDEI
VGWGPAGGYVFQKAFVEFFCDEGALRLLEAKIRREIGWVTWYAANSQVRDDEFITNLSDE
GRNAVTWGVFPGQEIAQSTTIERASFLTWKATFNIWSQWALLYPPNSDTRILLEKMRGTR
WLVSIVHHNFKEPNALWKLLLEQ
>A0A3M3E1F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas corrugata|TrEMBL
MTMSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQ
LESEVKIPAAPHLSCVGDSKDDLRTLLARYKAAGIQRIVALRGDLPSGMGMASGELRHAN
DLVSFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVNKANAGANSAITQYFFNADSY
FYFVERVRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQR
FGEDVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A167NLD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC 33097 / NRRL 1555)|TrEMBL
MKVIDKIKQAEKEGRHYWSFEYFPPKTPQGVQNLYDRMERMQRFGPEFIDITWGAGGSSA
DLTLEMVATAQSVYGLETMMHLTCTNMPLSMLDHALKTAKECGCQNILALRGDPPKGQTT
WESCADGFEHASDLVKYIRKHYGDYFCIAVAGHPEGHLDNPDKHDDLLQLKAKVDAGADL
VVTQLFFDVDLFLEFVKKCRQIGITCPILPGLFPIQNYNGLKRVISFNNNHVPQHIWDAL
EPIKDDDAAVKEYGINLTIDFIRKMWAAGINGFHIYTFNLERSTRLVLERLELVPDMESV
KPLPWSPSLTSKRAKENVRPIFWKNRTKSYIQRTETWDEFPNGRWGDSSSPAFGELDGYG
VSLKYPVKECLDMWGTPTSMDDISVLFAKYCMNKVPAIPWSAQPLDSETETIRQRLAAIN
LLGYLTINSQPAVNGAKSSHKVYGWGPKNGYVYQKAYLEFFVSPTDLDGLLAKIAKDPQV
TYFAVNNQGDLRTNTLNDHPNAVTWGVFPGQEIIQPTIVESAAFMAWKDEAFGLWREWSS
IYEPQSPSAKLLSNITDTWYLVNIVQNDFQDEGGIWRLFDLEIDGEISRKIRRSSIVLEE
>A0A4R3TSE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. Y-H1|TrEMBL
MTDVTTPATADGHLKRPAISFEFFPPKTEEMERNLWDTIKRLAPLEPKFVSVTYGAGGST
RERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPVGGIG
TPYASHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDAGAA
RAITQVFFDNDLYFRYRDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWFAAK
FDGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRARTAQ
KAA
>A0A1D8QY71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter ascendens|TrEMBL
MSLSRLSVELIPRSAEALAADVATVKAHFPAADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQPGLEEILVVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMQGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLEANIQFAQTVLKELAQEKGKAYLMPVRIKLEQY
LPALLDAVA
>A0A7G9G002|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium sunii NSJ-8|TrEMBL
MGNTKHTKEQIRERIQQKKLLFDGAFGTYYGGKYDTKQLPELANLEAPERVKEIHTEYLE
AGAQILRTNTFAANSFCMDMSKEQIEETLRSGVRLAREAMVAWRERTGETKEVYIAGDIG
QIPCDAPAQKDTLCREYEEICRIFLEEGVDFFVFETFSEMEELLPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGAIKEIDAVGFNCGVGPSHMYRILQTLYKPADKFLTALP
NAGYPQMVTGRMIFTGDNREYFVDRMQQMIALGVDMAGGCCGTTPEYISDLAGKLDFTQY
PQTQEKAEPEKKQAGTEDHSFYHIKEAEGGKKLIAVELAPPAGIDDEKLMDAAHLLQRSG
VDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGIH
NFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFAQAPVSYGGAINQGRRNLE
VEIGRVKKKMAAGATFFLTQPISTKESADRVRRIKEETGARILCGIMPFVSLKNATFMKN
EMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVIDMTEDFADGYYFSFPFNRVTMLEK
ILH
>A0A7W1XB24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoactinomyces daqus|TrEMBL
MRKPGLLEQLKSSLIVGDGALITYLYQLGVSIGHCSEELVLSTPSLISEVHQAYYEAGAR
VIETHTYGANRERLTRYGLDNKVIRMNREAVKIARDSVGDDAYVIGAIGSICAGRVPVFD
EEEYRAMYEEQATALLLAGVDGILLETFLDLKEILLAVEVIRPLTSLPIIAQLSMLEVGR
TRDAYTLTEAFGLLAERGADGVGLNCRLGPMEILRALEKTIVPEGMILTSFPNAGRLGMS
EGKLHYKSSPDYFEETAHLLVDQGVSLLGGCCGTTPDHIRKLAAALEGREKVKRTNPSSD
AIYDGAVESIAVRARSNPHVVDKVKSGRAIICEFDPPKDLDISQFLLGAERLHRAGVDAI
TMADNSLATARMSNLALGAILRDRLGIDPLLHVACRDRNLLGQQSHLMGIHALGIDQILV
ITGDPTRIGDLPGASSIYDLSSIELIRMVKQLNEGISFSGRKLKQKARFVVGAAFNPHVR
NLDAAVKRLMKKVEAGADFIMTQPVYDEQGALNLYEATKGIGIPVFIGVMPLIGYRNALF
LHHEVPGIKIPESVLKRMEATKDNKEAGREEGIQVAKELLEVILDKFSGIYLITPFSYWR
MTEELTRFIRLRDQQARRKLASR
>A0A2V7JP32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MLPRKRRPPLPENPLVARLLDPQQVIVFDGAMGTMLYNKGVFINQCYDELNLRAPDLVRD
VHKAYRKAGAEVLETNSFGANRIKLEQYGLSAQVADINRAAARIAREVAEDDLLVAGAVG
PLGIRIEPFGPTSLDEARAAFREQLQALKDGGCDVFILETFADLHEIEQGILAAREVDPN
IPVIAQMTIGADCHTPYGLSAEDLAQSLDAFGADVIGLNCSVGPQIILDAIEKMAPKTRR
KLSAQPNAGMPRDVSGRSMYMASPEYMGTYAHHLVQAGAKIVGGCCGTTPEHIAAMVEGV
RPLSPRQPRVPMKERRHIHPDLPPENPGVQPVPLAERSKWGRKIAQGEFVTSVEIVPPRG
VDASKMLRDTAALRDAGVDAVNVPDGPRAQSRMGALLCSILIEQQIGIETVIHYCCRDRN
LLGMLSDLLGASAVGLRNMLLITGDPPKMGPYPNATAVFDIDAIGLTNLVSNLNRGLDPG
GNPIGQPTRFTIGVGVNPAAIDPAQ
>A0A2V7ITW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYSKGFFLNVCYDELSRKQPKLVQEVHEAYVRAGAEILETNTFGANPVKLRSYGLA
DDTEQINQATAELARNAAGGHASVVGAIGPLGVRIEPFGALAREEACAHFARQVDGLLAG
GVDGFILETFSDMDEIHAALRAVRSRSDLPVIAQMTIGDDGLTHYGTGPETFAKQLTEWG
ADVIGVNCSVGPAGVLEAVEKMVKVTDRPISGVPNAGLPRDVGDRKIYLASPEYMASYAR
RMIEAGARLVGGCCGTTPEHIKKIRDYVASVVPRHPPVVVSRAEIRAPAGAEAVPLVQRS
RWGAKIARGELVTSVEIVPPKGVDATPMLEQCRALKAAGVDAVNVPDGPRAQSRMGVLPS
AILIEREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLTNLVFRLNHGLDPGNNPIGAPTRWAIGVGVNPGAVDLDRELSRFAWKVDAGA
EFAVTQPVFDPAQLEAFLARVGQFKIPIVAGIWPLISLRNAEFLANEVPGVSVPESVLAR
MRQAQDKGKEAALAEGVKIAREMFQQVKRSVQGVQVSAPFGRVEVALEVFG
>A0A287B634|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MDRPKAKCLPAGQCCPSLGVWALEAGISRSSVPPAISRSSAMVNEPRGNGGPGPRCEGSS
SGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEVTG
YLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACSEMGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMLIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>A0A7Y2ZGT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTRAPVPSLPDMLSDDRVHVFDGAMGTVLYGRGVFVNVCYDALALDRPEVVEEIHRAYVE
AGAEVLETNTFGANPVKLSAFGLADRTEEVNRAAARAALKAADGRARVVGAVGPLGIRIE
PWGPTSVDEAREHFLRQMRALIDAGVDGLLLETFADPHEVDVALSAAREAAGNRPVMVQI
TVGEDGRTAYGADAARELVRLAAAGADAVGLNCSVGPAVLLDVLEEAADRVSVPLLAQPN
AGLPRTVRDRKMYMASPDYMARYAERFAEAGVRFVGGCCGTTPEHIARIADVVRGRHPRH
APASVVPPPEAVRHPEVPLAERSAIGAALAEGRPIATVELLPPRGWDTTALVEAARACRE
AGVDAVAVVDSPRGRSRMSSLAASGILQRETGVEAVMHYTCRDRNMMGMLSDLLGAAGEG
IRNVLLVSGDPPVQGPYPDATAVFDIDAIGLTNVASGLNRGIDPGGADIGGPTRFVIGVA
LNPGAVDQERERSRFRWKVEAGADFAVTQPLFDVDALSRFLDATHDHPLPILVGLWPFGS
LRHAEFLAYEVPGVSVPEAILERMRRAQARGPDAARVEGIAIAREVREAVAALEPVAGVH
VGTPGADVGAALEVLAP
>A0A7Y8UYJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas allii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRTMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISTMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7L8RU42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter sp. SR38|TrEMBL
MTPPRPRQTDEHPDGIDLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSTSLLETVRLMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPYDFRPVHLGKKIAAGAQFVQSQYCFDVPMFRTFMNRVRDLGYDEKCY
ILVGVGPLASAKTAKWIRANVPGIHIPDTVIKRLEGAQDQKKEGKQLCIDIINEVKEIPG
VSGVHVMAYRQEEYVAEIVDESGVLKGRRPWKREARADDQRVAERLEHILHDDVTESQVD
MVKTAH
>A0A8H9WUG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTLLYGRGVFVNVCYDELNRRRPELVRQIHDEYVSAGAEILETNTFGANPVKLSSYGLA
EQTEEINRAAAELARAAAGKRASVAGAIGPLGIRIEPWGPTARSEAVNFFRRQVNGLLEG
GVDGFVLETFSDMSEIGCAVGAVRGLSDLPIIAQMTVGPGGKTAYGNDATLIARELTDLG
VDVVGLNCSVGPAVMLDAIEEMAEATNLPLIAQPNAGLPRTVRDRKMYLASPEYMAQYAK
RMIDAGVRFVGGCCGTTPDHVKQIRKAVASLQPKTVATAEPVAEAGVDIATEAVPLEVRS
AWGRKLARGEPVVSVEIIPPRGWDRAALIEPARRLKVAGVDTLAIVDNPRSVSRMGALSA
ALIVEHEVGIESLVHYTCRDRNMLGMISDLLGAAAAGIRNVLVVSGEPLLQGPYPDATAV
FDIDSIGMTNVMNGLNRGIDPGGNSIGAPTEFVQGVAANPGAVDQEREVERYRYKVEAGA
NFAVTQPIFDPEALERFLERVGSGSIPMIAGIWPFLSLRNAEFLAHEVPGVVVPDAIVER
MRGAQESGPEAALEEGVLIALEMIEAVRPHVQGYHLSAPSRRVDVALRVLREAGVSATA
>A0A4Y8UD71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Brevibacterium] frigoritolerans|TrEMBL
MNFRKELKERMLVGEGAMGTLLYSNGIDQCYEELNCTNPDQIESIHRAYLEAGADILQSN
TYGANFNKLKRYGLEDEVSRINRQGVILAKKAAKGKAYVFGTIGAQRSIRKSDLSMEEIK
RGFREQLYSLLMENPDGILLETFYDLEELETVLQIVKNETGLPIIANVSMHELGNLQNGI
HLNEAFQKLEQLGADVVGVNCRLGPHHMIRALEEVSLPKKASIAIYPNASLPDYVDGRLV
YKAVPEYFGSSALELREQGAAIIGGCCGTTPLHIQAVKHAIGSLAPVKEKFTKSREIEVI
EVNDRELELPLYEKAKTERTILVELDPPKKLGIESFMTGAEVLKKAGVDSITLADNSLAS
PRISNDALANLLKNQLNINPMVHITCRDRNLIGLQSHLMGLQTVGLNEILIITGDPSKIG
DFPGATSVYDLSSFDLISMVKQFNEGLSYSGQSLGQRANFKIAAAFNPNVKYLDKAVLRM
EKKIACGAQSFLTQPIYSVEQIEEVYEATKHLETPIFIGIMPLTSTRNAEFIHNEIPGIK
LPDNVRRAMALAGDDPVKSRVEGVNIARELVDAAREKFKGIYLITPFLRYEMTAELTKYI
RKVDSKQTSEVAVHE
>A5GBX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geotalea uraniireducens (strain Rf4)|TrEMBL
MNFSDRLRHEVLVGDGAIGTMLYAKGVSLDANFEHLNLVRPELVLGLHQEYVAAGAQVIE
TNTFGANYPKLHAIGLGNKVHDINLKGALLARRAAEGRDAFVAGSIGPLVKLKGEERDLG
EREMLEIFRAQVTALTEGGVDLFILETFSDLRQIEIALQVAKETGLPVVANMAFGENSRI
AGGIEAEAVAERLAAAGADVVGANCGAGPLEILRTVKRMGAVIELPIAAYPNSGFPEYVD
GRYIYRATPEYFAGMAAEMVAVGAALVGGCCGTTPAHIMRIAEKVRGLKPVPRAPAPPVH
AVERGGVREGTGPGFLAGWGKEKIVTVELDPPKGLDCSKVLIGSRILKDAGADAINLAEN
PLARVRMGNIALASLIQKEVGIEVIVHITCRDRNLLGLQSDLMGASLLGIRSILAVTGDP
ASLGEQAGASSVFDLNSFTLIKLLNGLNGGVNALGNPIGSGTRFTIGAAFNPNTQRMDVQ
AGRLAKKVVNGACFAQTQPIYDVQRLDEMIEQTAHLDIPILPGILPLVSERNAEFLHNEV
PGIIIPEEIRMRMRGKEKDEGVREGLAIAREFIAAVRERVGGFYLIPPFGRYEIAAELVK
YIKG
>A0A2V7R7R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYGKGFFLNVCYDELNLKQPRLVQEVHAEYVRAGAEILETNTFGANPLKLNSYGLA
DETEKINRTAAELARTASGGKASVVGAIGPLGIRIEPFGPTSKLEAQALFARQVQGLLGG
GVDGFILETFSDLDEMHAALLAVRAATDLPVVCQMTVGTDGLTYYGTDPDTFTKQLAGWG
ADVIGVNCSVGPAGVLEAVEQMVKTTEKPVSAQPNAGLPKDVGDRKIYLASPEYMASYAR
RMIEAGARFVGGCCGSTPEHIKKIRDYVASVVPRQPSVVVSRAQVQAPPDITPVPLAEKS
RWGAKLARGELVTSVEIVPPKGVDPKPMLEQVRALKAAGVDAVNVPDGPRAQSRMGVLPS
ALLIEREVGMETVIHYCCRDRNLLGMLSDIIGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLTNLVYRLNQGLDPGNNPLGGATRWAIGVGVNPGASDQDRELSRFAWKVDAGA
EFAVTQPVFDARQLEAFLKRVEQFKTPIVAGIWPLISLRNAEFLANEVPGVSVPEDVLQR
MRKAQEKGKEAALAEGVSIAREMFTRVKEMVQGVQVSAPFGRVEVALQVFA
>A0A6S7B5L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia ultramafica|TrEMBL
MNPIELSFEFFPPKTQEGIDKLRATRAQLALLKPKFVSVTFGAGGSTQQGTLDTVIDMAK
DGLNAAPHLSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGAVGELRYASDLVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFANKVKAGANSAITQYFFNGDAYFRFVD
DARKLGVEVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCKRLIDARVPGLHFYTLNGAAATKAICERLGA
>A0A1F8RU32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_68_14|TrEMBL
MAHPFLAALERRVLLADGAMGTLLHDRGVPGSACLDEQNLTNPELVQAAHREYLTAGAEI
IETNTFGANRLRLRSFGLADKVRQINAQGVALAREATRDCGHQAFVGGAMGPVGVGLASG
GDVTLRQAHRAFAEQAQALIESGVDLIVLETFPTLAEAREAVLAVREVAGDVPLVAQLTF
QRDGRTWTGEEPAEVARELHNAGADIVGVNCVPGPQAALDIIEEMARATKVKLIAQPNAG
HPRVVEREVAYPATPHVFAEYVPRLVAAGCVVVGGCCGTTPEHVAAMRDALRAEPGPRPA
EAPEAALAPPAILPLPDEELGPEEATLREKLAAGRFVVTVEIDPPRGLNPRRALQGAARL
KLAGVDCINVGDSPLAQVRMSPFAMAVLFRQQLGLETIVHVTTRDRNLLALQADLIGAHV
LGLRNVLCLRGDAPSGSGYARAVGVWDVTPVGLLRVLKGLNEGIDWAGNPMAQPTSFFVG
AAANPTAPSLEAESKLLRRKVEAGADFIMTQAVYDIEALERFLEQASRFKVPILLGVMPL
HSERHAEFIHNELAGVVVPEAVRQRMREAGEDALAEGAAIARELIAAARGAVQGVYLIPS
FNRYDLAAEFVQELKGEQVTAQTPR
>A0A848S1F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flaviramulus sp|TrEMBL
MKVTDHIKQANGKTLFSFEIIPPQKGRNIQELYNNIDPLMEFAPPFIDVTTSREEYVYID
KGEGLLDRKITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIHN
VMALRGDAMSHQKYFECTEGGHKYATELVSQIQNLNTGKYLHDVIESEHKSDFCIGVAGY
PEKHMEAPSLQSDLKRLKEKVDAGADYVVTQMFFDNNKYFEFVEKAKSVGINVPIIPGIK
PIAVKRHLQLLPQVFKIDLPETLINEVEKCKDNKAVRQVGIEWAVKQSAELKKAGVPVLH
YYSMGKSDNIKAIASQLF
>A0A2U2CYJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagicola sp. LXJ1103|TrEMBL
MTTPAVSFEFFPPKTLEASFRLWDTVQTLAPLAPRFVSVTYGAGGTTRELTRDAVGTLNK
HLGLPVAAHLTCVDASREETLAIAADFAKQGVREIVALRGDPPKGSTGFAPHPEGFANSC
ELISALAETGNFTIRVGAYPETHPEAASNMADIDWLKRKIDAGASEAITQFFFEADTFLR
FRDRCAAAGITAPIIPGILPIENWTAARKFALSCGTHVPALLDDAFTKAARDGRSDLLAV
AQGTELCSTLLDEGVDALHFYTLNRPELTRDICHALGLTPKAALRHVA
>A0A1N7SC50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia piptadeniae|TrEMBL
MNPIELSFEFFPPKTQEGLDKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLEMAK
DGVDAAPHLSCIGSSKESLRAILNEYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFRIEVAAYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DAHKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVAKRLESFGDDRDAIRAFGLDV
VTDLCRRLVDAKVPGLHFYTLNGAAATKAICGRLGL
>A0A1A2VF92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. E2733|TrEMBL
MSAGLECPKRMEFGPCGGVRPDGQCEMRPGACAFDDVVAWSGHQPATRPVRAPLVLADFS
CTPFDRRDVAATAAVLAPGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSINVETVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASTGVIAAAP
ETPTAPPVHARPARLVEKQRAGASLAVLNHVPRPGLVAEFVTTARAAGLTIPVIAAVAVF
TDTVSSAVLQGLPGLELDQAATERVLGAPDPVTAGIAEAVAEARALLAIEGVEGVNLSGL
ASASSPRIGAEIKAEVGRRIREEGRR
>A5GAM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geotalea uraniireducens (strain Rf4)|TrEMBL
MTSTLQSKLASGRFVLTAEVCPPKGSDCADFLEKSRKLSGLVDAINVTDNQGATMRISPL
AAAALLVREGIEPIFQITCRDRNRLALQSDLLGAAALGIENVLALTGDHISFGDHCAGKP
VFDLDSVQLLQAIKGLGAGQDLAGKSVTGAPAFFVGAAAAPEAEPFPLTFYKLEKKVAAG
AQFFQTQAIFDPERLRLFSEAVRPLKVKVIAGILLLKSAGMARFVTNNIPGLKVPAPLIE
ELEAAADPLAAGVAIAGRLAAACKPYCDGLHFMAMGREDLIPEILKAVGGRWSAVGS
>A0A2T0SKR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Umezawaea tangerina|TrEMBL
MTTVVERLHGRGPVFSVEFFPPRDSADELVLWRAIRELEPLDPAFVSITYGAGGSSRDFT
IRTTGRVAQETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILAVRGDPPGDPNGEWV
AHPDGLTYAEELVRLCRELGDFCVGVAAFPYGHPRSGDVDTDTEYLVRKLRAGADFAIAQ
LFFQPEDFLRLRDRVDALGCDTALLPGLMPLTTPRTLAKTIELSGAPVPPSVARRLDPFV
DDPKGFRKAGVDLVTEMGDRLLAEGVPGLHFYTLNRSKATREVVARLGLVPARA
>A0A1E4E2F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterium sp. SCN 63-126|TrEMBL
MLDDNLRASRKTADQRPPLQLSFEFFPPKTDAMEDRFWESIHKLAPLQPRFVSVTYGAGG
STRERTLRMVRRITADTGVAAAAHLTCVGASRDEVDEVVRGYREAGVKSIVALRGDPPEG
VGQPFTPHPDGYRNAADLVAGIRGIGDFDISVAAYPEKHPQSVDWDADIDNLKRKLDAGA
SRAITQMFFRNADYLRYLERARKAGITAPIVPGIQPIHSFRQISGFAARCGASIPDWMAE
RFAGLEDDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRS
>A0A435U753|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.14.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A2K9CFM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. S09G 359|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKADLRGLLTQYQQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISKMCEDLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3A3FNK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noviherbaspirillum saxi|TrEMBL
MTQKNFSIEFYPPKTPEGAEKLRVTRAKLAELHPKYFSVTFGAGGSTQKGTLETVLEIKR
EGHEAAPHLSCIGSSRESLRAILGEYKANGIRRVVALRGDLPSGYGASGEFRYANELVEF
IRAETGDWFHIEVAAYPETHPQARSPQDDVQSFARKVKAGANAAITQYFYNADAYFRFVD
DAHKAGVDVPIVAGIMPITNYSQLMRFSDMCGAEIPRWIRLKLASFGDDSESIKAFGLDV
VTGLCERLLAGGVPGMHFYTLNQAAATTALWKRLKLSE
>A0A7X2BPM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FSL R10-0399|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKDDLRGLLTQYKGAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDISNFVRKANAGADSAITQYFFNADSYFR
FVERVRAAGVMIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDANSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A6G8Q5U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacter tropicus|TrEMBL
MQDRRGALVGALRRPRYEVIPLPGIEDGVVEHVPKHIKITVTASPRKGLEPTLDLAGRLS
AEGFAVAPHLSARLIRDGAELGEILARLREVGVRDVFVVAGDAPEPAGEFEGSGALLRAM
DEIGHGLDEVGITGYPESHPLISDEVTIQAMFQKEPHATYIASQICFDTRIINEWVLRVR
RRGVGLPIYVGMPGAVSMTKLVRISSKIGLGESARFLQKYGNWFWRMFMPGGYSPDALVE
GVSLDHPELKVRGFHVYTFNEVEQTEAWRRGALERFGATPREERHEESTV
>A0A4Q3W154|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MDRHQHLRPQVAALSLPVQAVVAYAKGKNAGVLIEIGPPFLGRLTSLGDPAAVGLAVVPE
PAHRGKTGDRLGDGQQPQDNRENPAQSVQFRRVLPNFLASLGPASPSPLILGEVSFLDAL
RGGVLVGDGANGTLLQKRGFARLPYDLANLLAPEMVRETHAAYFDAGSDFVETNTYSASR
LRLPEDFDAREVNLAGARLAREAAPEGKWVLGAIGPAGKTMEPIGSLTEAEVRASVSEQA
AALAEGGVDGFLLETFTDVCELRAAVEAIKSVSDLPVLVSKAYIEDGEMLAEGLPVRCTK
QMDEMGVAAVGANCIVGPQRMLDLVRQIAEGTDLPILAFPTPGLPQLVKGQVVYDTDPDY
FARASLRLVEEGATVIGGCCGTTPEHIRRLRELLDARPPKAKARVRASRESRLPTDLPQS
EPSELAQKLKRGKFVTAIEMDVPRGLNLDKLVAGARALKIAGADCINVSDGARARLRMNP
AAVSTLIQQRVGIEVTMHLSCRDRNLLAIQADLLGWHALGLRNILAVTGDPANIGDYPSA
TSVFDIDSIGLCRILSRFNEGIDMAGYSVGLRCGFTVACAYNPLAMEPELELDRLRRKVD
AGAQVVYTQPVFEASIAEACAETCLSLGVPVLVGVLPLRSQRHAEFMHNEVPGIEIPRWL
REKISSTTDDASALEVGVEEARKLAETIRGCAQGLYLMPPFGSASIAERVMAV
>A0A6N6JVY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MEPFLDALKKRVLIGDGAYGTLFSRRGLSSPGLVSPLLNLAKPGFVKAIHEEYLRAGSEV
LETNTFGASRPVLEAAGAGDKAREVWRAGARIAREAAAQKAYVLGSIAPLGRAGLKLTPD
QRQAAYAEQVQGLVEGGIDAVLFETFSDLEDLQLAIIAANQAAPDTPVVAQMAFSIAGTT
TSGVSPESMIEGLKELRVSMLGANCGGGESAAIEVVRRMADHTDKPLSVFPNRGLADFDE
TGRPVYIEGADYFAKSARRLADLGANLIGGCCGTGPEEIRKLKGLLAGRRPSVRHKAVSS
SSGRRQAAVPPGPRVQKTLAADFARGGVVIAEVDPPRGIDATEQMAGARLLMEAGIDAIT
IADNALSVMRMGNLALAQLFMAEFKARIVLHVACRDRSLLGTQSHLLAAYALGVSNVLAV
TGDPIATQAHQGSSGVFDMSSTKLIELISRINRGEFTAESDGELRTNFYIGAAFNSATRS
LENESKRLMRKQQAGAGFVMTQPVFSVESARAVAAAIAPLNMPVALGIMPLVSERNAEFL
HNEVPGIQIPEAIRGRMAGKSGKKGRAEGLAIARELMEQVADSVAGFYLITPMDRYEMIA
ELTTFARSLRVKARA
>A0A7C5GSS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MGFIEELEEKILIADGAMGTLIYAKGVPKGHCYDELNISAPELIAEIHREYIEAGARIIE
TNTFGANRYILERYYDLGKRTREINLMGAKIAKEAAKGKGVYVAGSVGPVTRVWESEPSF
SPSDLRSIFKESISALLDGGVDLIILETFTSLEELVIGYKTALELAGEDFPVIASLSFLA
EGRTLMGVEPAQFAHEFQRLSANLIGANCGTGPKPLLDTVRRIGKIFSGFISAMPNAGFP
NFSDGRFVYPATPEYFASFAVRAARSGVNIIGGCCGTTPEHIRAMSRAIEKVRPVKRKII
TFYEGKFPKPITVPRPLPPFVAKLKEGFIFSVEIDPPKGSDVSKIIEQCNEFGSLGGSAV
NVADLPMAKLRMSALSLAIILKRETKLDIILHITARDRNIIALQSDLLGAYANGVDIILA
LRGDPPSLGDYPFATGVFDLTSAGIVKLASAFNTGKDTLGNPIENVTNFSIGVAFNQNAQ
SIDSEFKRLEMKIRAGAHFIQTQPVFDPQTIDPLVEFARYRDIPVIATVMLLSSVAQAEY
IANEVPGIKMPKSLIQRLQLAEDPEEESINFSIGLISELMGRVNGVCLVFPQGKFSLVRG
LMTRI
>A0A7V4EP96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MSDELKSGSNLEKVFKAGHFAVTCECGPPKGADIEVIKKKASYIKGKVDAANVTDNQTAV
VRMSSIATSAILIKEGVEPIMQMVTRDRNRIAAQSDVFGAYALGIRNMLCLTGDHQKFGN
HPRAKNVFDMDSIQLLDVVRTIRDEGKVNSGEEVEGGIGMFLGAAENPFGDPFEFRVHRL
AKKIAAGANFIQTQCIYDMDRFKTFMKQAVDMGLTEKCYIMAGLTPLKSAGMANYMNKFV
AGITIPQPLIDRIKGVEKGQQTEEGIKILMEQIEECRNIPGVAGVHIMAIEWEEKVPELV
ERAKLLPRPQV
>A0A7R6YL89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 131-3-5|TrEMBL
MSARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A7V7WMS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MTRLKQELQSGRFVVTSEIAPPKGPDLSDFLEKARLVKDRVVAINVTDNQRAIMRLSSLV
ASAALVREGIEPIYQLACRDRNRLALQSDLLGAHAFGIRNILPLTGDAVAQGDQKEAKPV
FDLTSVKLMALVQKLNQGLSYGDHPLSGKTDFFVGGAVDPKNIGAKAFFQKMEEKMKYGA
AFFQSQPIYDLAQVEAFYRYCEEHRVKSLIGVLLVKGPKQAAFLNSHVPGIRIPEEIIHK
FNGAAEPLRVGIDFAAQQIRELRAISHGVHIMTVGREDLVPEILDRAGL
>A0A4P7BY67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosococcus wardiae|TrEMBL
MHSQRNYPLIFSCEFFPPKGDEGASKLRRTRKKLARLHPRYYSVTFGAGGSTRDRTFETI
SAIQAEAKKTGIEAAPHLSCVGATRGNIREILKAYQQQGVKRLVTLRGDLPSGMVDPGDF
HYANQLVEFIRAETEDYFYIEVAAYPEVHPQARSARADLMNFKRKVEAGANSAITQYFYN
IDAYLRFVDRCESVGIDLPIVPGIMPINNYVQLARFSDACGAEIPRWLRKRLEEFRDPAA
MSAFALDVISDLCHRLLESGAPGLHFYTLNRADPTLAIWNNLGLKVKPADLSTAAKT
>A0A2E0BG78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MIKKKLLKSIEIIPPRYKIDNQLLRNLSKYQNNFDFLDIACSPMANLRISAITFAHNLII
KGVKKEKLIINFSTRDKNTLALQSEILGTYGMGINRLLIVKGDKISYGNSLKSKEVFEVS
TNELIKIVDNLNNGHDYSSNKLKFKTKFNIGSTLNIDSSYSIVKKTIQKRIKSGSNFFIT
QPLYSEKDFVLLSKLSKNKSYQILAGILPIKNKKTFVNLIKKINGISKVNELFDLLSGAN
EKDFADISTKYLLNLLEKYKSELDGVHIMTSGDIRLASKIADKI
>A0A1E4JH80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. SCN 67-31|TrEMBL
MTTSLDALAEARRAAASPLFANLEGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLAPRFV
SVTYGAGGSTRERTHATVARIASESAVPPAAHLTCVEASRAEIEEVARAYWDAGVRHIVA
LRGDVPGGGAYRAHPEGFANAVELVAGLKRIAPFDISVAAYPEVHPDADCPQADLDNLKR
KLDAGATRAITQFFFSPDAFLRFRDAAAAAGIDAPIVPGILPVSNVSQTRRMADMCGTAI
PAWMIALFEGLDDLPAARQLVAATVAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHMLG
LRPVAPAKDKAA
>A0A4R9DUP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. AN2|TrEMBL
MAHTPSLSFEIFPPNPAAGNEKILSALRHMQDLAPHFISVTASNNKYNLEDTTVRLADYI
HNDLGIPSIAHLPAIYLTKEEVTNILVALDQIGVHNILALRGDRIPNITPREDFHYATDL
ISFIKDEAPHFDIIGACYPESHPDSPNQVSDIKHLKTKVDAGCSSLVTQLFFDNEVFYDF
QEKCLLAGIEVPILAGIMPIINRNQALRLLNTCENIRLPRKFRAILDKYEHDPESLRAAG
LAYAVDQIVDLVTQDVAGIHLYTMNNPQVANYIHHATYSLFKHSAV
>A0A2D8B8W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MSSSRALSLEFFPPRDENARGKLTAAAKELEVLNPAYVSVTFGAGGSTREGTADAVDLLQ
KLGYEAAPHLSCIGASRAVLGDILQYYKDQGVRRLVALRGDLPSGMGMNKGELHYAVDLV
RFIREQTGDWFHIEVAAYPEVHPQAKGAQADLNHFVEKVRAGADSAITQYFFNADAYYDF
VDRAREKGVGVPIVPGIMPITNHNQLVRFSDMCGAEVPRWIRQRLSDYGDDLASIRAFGA
EVVTRLCQDLLDQGAPGLHFYTLNNAGATLAIARRLT
>X0PJU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus wratislaviensis NBRC 100605|TrEMBL
MTRTPSIVDRIRSSSDGRVPFSVEFSPPRDEAAEARLWRAVREFERLGPAFVSMTYGAGG
STRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRGISNILVLRGDPPGD
PLGEWEKHPDGVEYAEELVRLVRDLGDFHVGVASFPEGHYRAPDLAHDTRYLVSKLRAGA
EYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSVRRVLELSGSSLPAH
LEKRLATAAGDGPEENRAAVREIGIDVATEMSERLIAEGAPGLHFITLNFARATSEVLAR
LGDKVGSGVADPAPVTSARVS
>A8N945|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)|TrEMBL
MRISQKIQQSAKEDKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPREKVDTALKEAKEHGCRNILALRGDPPMGKDE
WEAVEGGFVHGIDLVRHIRKHYGDYFDIAVPGFPQHMLLPPEERDNEIRWLKEKIDEGVN
FIFTQMFFDVDIFISWVKAVRAAGITIPIVPGIMPIQTWNGFIKATNLASTKIPQFFLDA
LEPVKSDDEKVREVGTKLVADMCRKILDSGLGIRGLHFYTMNLEKGTRMLLEELNLVPRI
ETIKPLPWRQCLTPNRRNETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGEID
GYGTAIKQTKENALKLWGYPTTLEEVSVLFAKFCKGELDALPWSDSAPSKETSIIATQLA
KMNELGFLTINSQPAVNGARSDDKIFGWGPSNGYVYQKAYLEFFVDPALLQLLLKHLERD
TNITYHVINKRGDLQTNTHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGAQ
WARLYEHDSPSQKLILNLMENYALVNVVHNDFHNPDAIFEPFWKAGAEWTALKKAEQGDA
APSAPVANGVVNGH
>A0A366A4Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 2017V-1124|TrEMBL
MGYTHAGHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQNIVALRGDI
PAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVAAGIGVEIVPGILPVSNFKQASRFAAQNNVKVPNWMVKQFEG
LEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A1C7NVM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararhizobium polonicum|TrEMBL
MPIHTLYPAERGNLRLSFEYFPPKNDDMEVQLFQTVADLSAFNPAFVTMTYGAGGSTKAR
SLTAVRRMIHDEHIANTAAHLTCVGATRAEVDAIVSEFIDNGVRHFVALRGDPQGGIGAR
YAPFPDGYENAAALVAAIRSAGDFDISVSAYPEKHPESPDVDADIDMLKRKVDNGATRAL
TQFFFDNNDFERYLERVRRAGIHIPVVPGIMPINNLASIRKFAGLCGAKVPDAIVTRLIH
LDESPEERFKEATHIAAEQIVDLARRGLRDFHIYTMNRSPLVAAVCDLVGFERLAPAATQ
SRSAGAAA
>A0A522N273|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKIAEILAARRPSFSFEFFPPKSEAAMAALLETVATLRPLQPAFVSVTYGAGGGTRARTI
EITKTMKRDLGIEAMAHLTCVGATRDELRATLTDIRGAGIENVLALRGDPPAGEAAFAAV
TGGLAHGADLVRLVREDHSLCVGAACYPEKHVEAADPADDLRHLRHKVEAGAQFLITQLF
FDNQRYFSFVERARRAGIDVPIIPGIMPITNAAQIERFTRMCGATIPPALVAELEARGEE
PEAVIDLGVAYATLQCVDLLARGVPAIHFYTLNKSPATRAVVSALLAARPWEPARGRRYV
ENADSVAESALSLPTTL
>A0A0R2T540|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|OM182 bacterium BACL3 MAG-120619-bin3|TrEMBL
MSTDTSHFSIEFFPPRTPAGEEKLDIVHAELSKLGPEFFSVTYGAGGSTRDGTKRAVTRF
REAGSRVAPHLSFGGSDEGDILKLLHEYKEAGIDRLVCLRGDAPSGMGSASLYRYANELV
EFVRKETGDHFTIDVACYPEVHPQSRSVESDLEFFKAKVDAGANSAITQYFYNADAYFGF
VDDCARAGINIPIVPGIMPITNYANLARFSAACGAEIPRWLTKRLEFLEHDDHALREFGL
DVVTDLCEQLLAGGAPGLHFYSMNQADSVTRLWQNLLED
>A0A1U7NL04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dubosiella newyorkensis|TrEMBL
MSKIDTLLKQGPLLFDGAMHSYQGSQTSKEVLKDYIDAGAMAIKTNTFSCSSSSLPWNEI
EQKIEFEIEQAKEAAHEETLIFANIGPCPREDDAFSIYKKQVDLFLKHGINAFLFETISS
LNGIEAISDHIHQIAPEAFVLVSFAIHENGISDQGETIQSLYDALAQSSIDAIGMNCRVG
PKHMLELLKTLVRCDKPLYISPNAGYPTVLGWNVYYNGSPAYFAQMMKEIRLLGVEMIGG
CCGTTPAHIAAMKEAILLLPSYIPYHNPRTIQNDHPRSGKDWRNTIAIELDPPKNDQLDA
FMKGVYAFHKEGVDLITLADCPVGRMRADSSLLACKIKKETGIDPLPHITCRDRNLNAIK
ALLLGLSAQEIHQVLFVTGDPLPSDTIEEVKAVYHFNSRKLMKAVHQMNELSSPMALFGA
LNINAHNFDQQLVLAKEKEANGAIGFLTQPIHSWEGLQNLKKAKEHLNGVILAGIYPIVS
YKNALFLSNEISGMRIDARIVEMYKDKDRKEGEQIAIQISKAIMKEALPYCDGFYLMTPF
QRIEMMLPLIQEAKDLLKKTGTN
>A0A0M6WLE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] rectale|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNQYHVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAGDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>Q634T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus (strain ZK / E33L)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A3D2DM96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MDNIRDYLKDNILITDGAFGTYYAGLYDTRELPEKDNINYKDRITAIHREYIEAGARLLR
TNTFASNTINLDTDIEGVRANIKAAVQNARQAALLSGKEVYIAADIGPIPNDNMFDRQIT
ENEYVQIVNTFAKLGVNIYVFETFSDISHIIEAIKAVPKDAFIIVQFAINQYGYSSSGLS
ARKLISLADEIDSIDAVGFNCGIGPAHMEQFVSRNRKYTKKIFTALPNAGYPQVISGRMV
FSDKNIEYYSQKVCDLVRAGADIVGGCCGTTPDYIKNISEMIRSSHISCNINIDTDGDFN
KTSVKNSAFYCGKEGKKLIAVELAPPFDSDADKLMDAAHYLKEKGVDVLTFPDSPSGRTR
ADSILIAAKVSRQTGMCVMPHLCCRDKNAIAIRSQLLGAHINGINNFLVITGDPIPQMIR
SSVKSVFNFDSVGLMNIIEDMNEDQFKHEPVVYGGAINQGRKRLDIEISRVKKKMEAGAA
FFMTQPVFSDEDIKRLSTIKKETGARILCGIMPLVSLKNATFMKNEMAGIDVTDEVLSRY
SEDMTKKEGEAAGVKLAVDMINKTKDIVDGYYFSFPFNRVYMLEDILSMSQI
>A0A537EWL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MKLSERAKYHTIVTAEVIPDRVVPAHLPLLDGRVDAITIPALRNGENDPSYPSEFRVTPQ
TRSVASAVIVKKTGFEAVPSLTCRDFRRSDLPLLPVLFKKGLENFLVVFGDPYPNYEIKT
YDFKRAEDLIRGIRSVFDGQRPCIGAVTNQYALDREKEISRTLSKVDAGADYLVTNSAFD
DYYVLDYIDALRSSGLKVPIFVQLSIPHGLNNLLFVSRRFGIPVPESVKETVSRDPLGGG
VQVIARAFAGLRNEVSGIHFSYLFRSHNPIPTYTHLLDAIETDWQLVGSLQATLRT
>A0A7Y3J5E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steroidobacteraceae bacterium|TrEMBL
MSPPLNVSFEFFPPADEAGERALAVAVSRLAPLGPQFVSVTHGADGSHRARTLDWARRLH
REWGLPVAPHLAAAGSSRTEVRALAARYWQEGFRRLVALRGDVPTGPEKATVGGKGVVEG
YGFASELVADLAPRYRFEIFVAAYPEGHPDGGGVEADVRNLQRKIDAGASAAITQFFFDT
DAFLRYRDRCRAAGIEVPIVPGILPIRRFEQVLRFAGRCGASIPAWLHRRFEGLEADGEA
ARRVAMQVAVAQVRRLRAQGVEQFHFYTLNRADPTHAACEALQLRPPGAQVAPSSQAPPR
VGVDLAQHRGAAE
>A0A3G8JEU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia insulae|TrEMBL
MPFSVEFFPPKDEAAEARLWRAVRTFERLGPAFVSMTYGAGGSTRDRTVRITGQLAAQTT
LLPVAHLTAVNHSIEELRALVGAYADQGITNILALRGDPPGNPLGEWTKHPDGVEYAEQL
VRLIDDLGDFHVGVASFPEGHHRAIDLDHDTRTLVDKLRAGAEYSITQMFFDVDDYLRLR
DRVARADPEQGNKPVIPGIMPITSLASVRRMTELSGSVIPPDVQERFAAAAGDGPEEDRE
AVRAVGIDFATEIAERLIAEGAPCLHFCSLNFAKATSEVLERLGVDMTSVLPVASAAR
>K4LI31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermacetogenium phaeum (strain ATCC BAA-254 / DSM 26808 / PB)|TrEMBL
MKEINPEKLKAGSNLEKVLVSGQFACTGEIGPPTYASFDVIDKHAEEMRGLVDSINFTDN
QTAVVRLSSWAASVHLIQLGLEPNLQMVCRDRNRLAMQSDLLGAYALGVRNVLCLTGDHQ
AFGNHPGCKGVFDVDSVQLIHMLKRLRDDGCFECGAECKVPPKFFIGCAENPFGDPFEFR
AIRLEKKIEAGADFVQTQCILDMERFELFMEKVRERGLHKRAYICAGIMPVKSPRMARYM
QTGVPGMLVSEEFCQRLEKAEDPKAEAVEISVEYIKRCQQIEGVAGVHIMAVAWESIVPT
IVKKAGLAPRPTF
>A0A3D1NUJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNRYHVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>A0A0R2ZRQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas trivialis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGAGGSTRDRTINTVLQLE
SEIKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANEL
VSFIREESGDHFHIEVAAYPEMHPQARNFEHDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITQMCEQLLQGGAPGLHFYTLNQTEPSLAIWNNLKLPR
>A0A1V4A702|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces tsukubensis|TrEMBL
MAFGTASTRTTHPRSVRELLSSGKPSYSFEFWAPKTPKGERSLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATQQIAEDTTLLPVAHLTAVDHSVAELRNMVGQYADAGIHNILAVR
GDPPGDPMGEWVRHPEGVLYASELVRLIKESGNFCVGVAAFPEMHPRSLEWDTDVRYFVE
KCRAGADYAITQMFFDPSAYLRLRDRVSAADCETPIIPEVMPITNIKQLERVASLSTSQF
PAEVKERMLAAKEDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHHQA
>A0A259YCR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 06-469-3-2|TrEMBL
MPDGLRWAATYDLRVSEDSVRGRSSRGFVTRTPSIVDRLRTEPEARIPFSVEFSPPRDAA
AEARLWRAVREFEQLQPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSV
DELRSMVGSYADRGITNILVLRGDPPGDPLGDWEKHPDGVEYAEELVRLVRDLGDFHVGV
ASFPEGHHRAGDLEQDTRCLVGKLRAGAEYSITQMFFDVDDYLRLRDRVSAFDAEQGAKP
IIPEIMPITSLRSVRRMLELSGTTLPSHLDEKFTRAAGSGPEEDRAAVREVGIELATNIG
ERLISEGAPGLHFITLNFARATREVLSNLGLAAARV
>B6G131|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium hiranonis (strain DSM 13275 / JCM 10541 / KCTC 15199 / TO-931)|TrEMBL
MGRLKDSLESGKFTVTCEIAPPKGTDISHIMECIEVLKGKVDAVNVTDFQSAVVRSTSLV
TCKILKDNGIEPILQMTGRDRNRIAIQGELLSAGIFGIENLFAITGDHTSKGDHPQAKNV
FDLDSINILKAAEYISFGRDMNHNELNGHPKFYMGAAVSPGFVPIEIQIIKMIKKIAAGA
KFFQTQAVFDIETVREFRKRTKNFECKVLIGVIPLKSPGMARFLNRNIPGVDVPENIIER
MESVGKENYKEEGMKIAAEFIKQLKEEKLCDGVHIMSVGAEKNIPKILEMAGIEI
>A0A3D2DLC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp|TrEMBL
MKVTEILKQDKPTISFEVFPPKKDTDFADVEAAATSIAELNPSYMSVTYGAGGSTKGLTI
KLAEGIQNKYNVPTIAHLTCVCADKAGISQALQDMKAAGIKNILALRGDIPKDYSGEIFT
EFAHASELVKLIKVSGDFCVGGACYPEVHPDSTDKKADIDGLRKKVEAGCEYLTTQMFFD
NNIFYNFMYRIREAGIMVPVVPGIMPITKRAQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMRQAGVLYATDQIIDLIANGVNHIHIYSMNKPEIARAIYDNLSHIII
>A0A0M1J5E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromatium sp. WMS3|TrEMBL
MQHFQRKVQAGANAAITQYFYNADAYFAFRDECTRLNIEVPIIPGIMPIINYTQLARF
>A0A852WNM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces hippuratus|TrEMBL
MASTATDASGADCRPRLPLSFELFPPRTDAAALALGRTIDRLAEVDPAFISVTFGAGGSS
RARSLTVLRYMLEHTHVEPMAHLTCVGSSHAEANRLVREFLDAGITSFLALRGDPPANAD
PDAGIGDLGSAAELVQLIHRVQEEREPFGQVGVPGNPGASRIKARPRPERVAVATFPTGH
PRSRNLGHDVDTLLAKEIAGANLAITQLFWRADDYLGFVERARAGGVMIPILPGIMPVTN
PARLGRLTELTGVEPPAELAIELEIEPDAAAQAELGIAFATRLAAEVIAGGAPGLHLYTF
NRHEAVLDVVDRLGLRTDRFADERNTAR
>Q21NJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)|TrEMBL
MSEQQEFRLSFEFFPPKTDVGREKLITVRKELNDIHPDFFSVTYGAGGSTRDNTKGIVKK
MREEGLNVAPHLSFGGDTEQTILPLLQEYKDMGVDRIVALRGDMPSGVGGAQQLVYANEL
VAFIRKHFDDYFHLEVAAYPEIHPEATSYLDDVRYLKGKFDAGANSAITQYFFNPDAYFY
FMDQCQKEGIDQPIYPGIMPILNYRNLARFSDSCGADIPRWMRKRMESFGDNQEALISFG
IDWISELCDTLLDAGAPGLHFYTMNQTEPTATIIKNLGLEDAPDAQEHNHEGCGHEH
>A0A542KBP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SLBN-31|TrEMBL
MAGEALRALLEHVRYEVLPAAATEEKVLAHVPHDVVITVTASPVKGLEPTLELAGRLAAH
GYRVVPHVPARLLRDDVHLKEVVARLREAGVDDVFVPAGDADPPAGAYDGALPVLVRLGE
LGAPFARVGITGYPESHPLIHDDLTVQSMWDKRAHATYIVSNLCFDARVLGEWIARVRRR
GVTLPLYVGVAGPVQRAKLLAMATKIGVGESTRFLRRHPSWFLRFAAPAGHAPQRLLERA
DQALTAPSSGVAGLHLFTFNQIAETERWRRAWRERLGG
>A0A1I5ESI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio sp. UC1225|TrEMBL
MFKDMFERDSSLSFEVFPPKKDDEFENCYKVLDSLAEINPDFISVTYGAGGSRSKKTVDI
ASYIQNQLKIDAMAHMTCVGSTEEDILAVTKDLEAVGVNHVLALRGDKPRDMSDEQFEQR
IFPHATDLIHFINQNTNLIVSASCYPEKHPEAISMDSDIAFMKMKQDMGAEMFISQLFFD
NSDFYRFIERARRAEITVPIVAGIMPITSAKQIGSTVTLAGSSVPKKLADICAKYGESPE
DMRKAGIAYAIDQINDLKRCGMGHIHIYCMNKPKMTKEICEGIC
>A0A659LIV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E2661|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2N1CZH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Choline-3u-10|TrEMBL
MSQTRSHSFSFEFFPTKTDAGHEKLLATARRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVSTAPHLSCVGDTKAELRELLNIYKDAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARHFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVDTPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMESIQA
FGTQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAVWENLKLVR
>A0A2N8C5U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FW306-2-11AA|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1A9XIB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glossina fuscipes fuscipes|TrEMBL
MVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEVVWRNIHFLVWDLGGQQSLRAAWSTY
YTNTEFIIMVIDSTDRERLAVTREELYRMLQHEDLSKASLLVYANKQDLKGSMSAAEISR
QLDLTSIKKHQWHIQACCALTGEGEQQLRKYPETQQLKIAIAEKIAKKEYFYGIEILARN
HNPKLMLDYTKFGKMLPLFTSLVWLGLDYSRVANVDKVESVRLAKKLTDNQHEMLIAPHL
SCYGLDTKRLKEFMELNFTNIVIVRGDQYDSQQEFKYASQLVAQIRRECQDSITIAVAGH
PEGHPSISTVQEDMQFLIEKINSGADLIITQVCFKAQALIDFIKSCRLNSIDIPIILGIY
VPDNMKSLQFLMELTKIEMREEDLQQYRYYAGKGSEEFRFFAAQKAAQMILTVLKAKDIN
IYGIHFFTMNKFDMVTKVLEELRKCINI
>A0A4S3ZU76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium supellecticarium|TrEMBL
MKVTQHIANAAGKSLFSFEILPPLKGQNIQCIFDNIEPLMEFKPPFIDVTYHREEYEYKE
LPNGLLEKKIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFNREDTENFLIDMDFLGIDN
VVALRGDAVKSEIYFKPEKEGNQYASELVTQINNLNNGIYLDADLQNTNKTNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNRKFFDFVAKCRKEGIEVPIIPGLK
PISTKKQLNQIPHRFKVDLPDELIMEVVKAADNETVKEIGIEWCIAQSRELIAAGIPVLH
YYSMGRSESIRKIAATVF
>A0A2A2Y283|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium AMD-G3|TrEMBL
MSRQQLINALRSPVRPTVSVEFFPPKDAEGGARMLKVAATLKPLGIDFASLTYGAGGTSR
DTTITYGAELVKMGIPLIGHLTCVGHSRTELAGIISQYDKAGFSGILALRGDPPKGQQDF
VAHPEGFAHAQGLVRQITAEQPGRFAIGVAGFPERHPDAVDDLSDIRFLAGKVAAGADFV
TTQLFLDNEDYFRFVARARAAGVSVPILPGIMPVLSLKQARNFCGFCKARIPDALVRELE
ACGPDEEAQRKVGVSWAVRQARGLVARGAPGYHVYILNKAESAVELFAALRD
>A0A7X7BT57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium|TrEMBL
MSSQYVEILNQSLAEFNQPIEVSFEFFPPNSEAMVKTLWNSIERLGVLSPKFVSVTYGAN
ASTRDRTHKVIRDIMKHTAIEAVPHLTCVDTSEAELVEIAQDYWNSGVRHILALRGDVPK
GSPNPDIYADYLVKLLKKTHDFEVSVAAYPETHPDAKNAQADLIHLKRKVDAGADIAISQ
FFFDIDSYLRFRDRCVAVGIEAEIVPGILPVSNYEALMKFAGSLNVKIPSWLHKRYEGLE
NDPETRKLVGASIAIDMVRVLNKEGVKNFHFYTLNRSELTYAICHTLGLRPNAAGRI
>A0A1D8S4V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halodesulfurarchaeum formicicum|TrEMBL
MEADDRFAVTWELIPGRGSHEPQQEEVFEDAETAASGDVVDAVSLTDNPGGTPALSADYL
GMKLKERGIEPLVHFTTKDKNRNQIEGLLHALEREDIHNILIMSGDHQGPAFEGQAKAVY
DLDPVQTLDFVSDLNDGFEFEDNFGRHNELAETDFFPGAVVSPFKRLEAELMPQYWKLEM
KVEKGAEFIIPQVGFDARKFHELIKFIDEKDLDVPVIGNLYVLDPGSARAMNENRIPGAI
VTDDLREEVEAEQEGEDPHQAMLERAAKMYAFMKGMGFAGVHIGGHAADYDDVEYIVERG
EELAPDWEEYVSEFDFPMEDGFYYYERDPETGLNADEHAILPENPSTGLKYKGFKVAHEL
MFEPDGPLFGPMRWFSKKVDDSALEEPFTTFERVTKTISNDCQECGNCALFDMAYLCPMS
QCPKNERNGPCGGSYDGWCEVYPGEQECIYVRAYRKLKADGGLEKAREKLRDTYIPPPDY
DLEGTSSWLNYYLGRDYAGKRVGNEVADD
>A0A7J5VDW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MQENRFKEALLNPNIFPVTWELVPGRGAKEATQDKAMALAGQAASGGNIHALTLTDNPGG
TPAMSADSMGGEIMKLGIEPLVHLTCKDKNRNAIESQLYALDRAGLRNLLVMSGDYPVSG
FRGRPAPVFDLDPIHTLQMIADMNRGLTYPGIKGNVQHQPSDFFPGAVVSPFKATEAEQM
VQYYKLKKKIEAGAQFIVTQLGYDARKFHEVLLFMKQNNFNIPLVGNIYILPFGAAKMMN
RNDLPGSVVTDKLLADIDRERNDPDKGERARTLRAARMYAVMKGMGFSGVHIGGHNIKYE
QVEEIIRQGEELTSQWTDLIRYFDYPVPGGYYYFEHDPATNLNRETLTDRQSRPLDAKVE
CSYRFSRLSHQLLYEPGKNLYGVMKGLIVKVAGSKMEAFFHKLEHLTKVVLFDCKDCGDC
ALIDVAYICPMSQCPKTQRNGACGGSFQGWCEVHPGKRQCIYVRAYARLKKYAEEVRLSK
DIVPPCNWDLYQTSSWINFYLGKDHTSKKQGGHSPEN
>A0A7W7L7D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces netropsis|TrEMBL
MRELLARGERSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSVTYGAGGSSREGTVRA
TERIATDTTLTPVAHLTAVNHSTAELRNVIGQYADVGIRNMLALRGDPPGDPMGDWVRHP
KGIDHAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADFAITQMFF
YPEDYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFAQLSNAAFPPDLAERILAVKDDP
AAVRSIGIEYATQLCTRLMAEEIPGLHFITLNHSTATLEIYENLGLHQRS
>A0A376FGW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter asburiae|TrEMBL
MKWSKPLWSSIDRLSSLKPKFVSVTYGANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDA
TRDELRAIAQDYWNNGIRHIVALRGDLPPGSGKPDMYAADLVALLKDVADFDISVAAYPE
VHPEAKSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPV
SNFKQAKKFADMTNVRIPLWMSKMYEGWTTTRKPASWWGPISRWTW
>A0A354C4S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MRIKDIFTQKKFSLSFEVFPPKREGNLENLYTTIQELKEAKPDFISVTYGAGGSTREKTI
EISSTVRNEFHMEVLAHLTCVQSTRHDIAGILDALKEHNVENILALRGDPPEGTKIFTKI
AGGFGYANELVEFIRAHDDFSIGVAGYPEKHSEAPSHHADMMNLKRKVDAGADFIITQMF
FLNDCFYNFRDRAEALKISVPIIPGIFPILNHNQFTRLVSLSGAQIPNKLAEKIEKNKEN
PEEVEKYGIEYAINQVANLIKNEIAGLHFYCMNRSRPVKKILDELTLRR
>A0A246NKE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. VS1|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEATLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRAIARDYWNNGIRHIVALRGD
LPPGGGKPDMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNAMFD
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPTLAA
>M2NWL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis azurea DSM 43854|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTPRTLHTSIKLSGAPAPRRLLDRLEPLA
DKPKAFRAAGIDAVTELCERLIAEGVPDLHFYTFNRSKATREVVNRLGLVPARA
>B6B7C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium Y4I|TrEMBL
MTTPKISFEFFPPKNLEASFRLWDTVQVLAPMDPRFVSVTYGAGGTTRTLTRDAVATLHN
SSGLNVAAHLTCVNASKAETLEIADQFAEAGVTEIVALRGDPPKGEGKFTPHPEGFADSV
ELIKGLAARGGFTIRVGAYPDCHPEAASQAANVEWLKRKLDAGADEALTQFFFEADTFFR
FRDACEKAGIDGSKLTPGILPIENWKGARNFAKRCGTVIPDWVENAFDKALRDGREELLA
TALCTELCSDLLEGGVDKLHFYTLNRPELTRDVCFALGITPKVALENVA
>A0A8J5BH05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yarrowia sp. B02|TrEMBL
MSTITKLIAGLKPDEKFFSLEFFPPKTQNGMANFRARLARMAALKPLFITITWGAGGSTA
KKSLDIASECQSMGLDVCLHLTCTNMDPALIDQALEAASKAGICNILALRGDPPRGEEYW
QPASPEFQHAADLVKYIKKKHGDKFCVGVAGYPEGHVDGSDASHQDFHHDLPYLKEKVEA
GADFIITQMFYDDSKFLEYEKAVREFSPALKEITIIPGLMPINTYTSFVRAARLSHASVP
PAILDRIQAVPTGNDQQVKDIGVEVVSDIVNDVYTKTNKTVRGFHFYTLNLERSVARILE
RSGFLTVEEDIAVEEATGSTASTTPNKTPLRRRSSASHRNRVVDDSRHAPDAPKEEPDLT
TLALAIASGEGAVGREAVWDDFPNGRFGDSSSPAFGEIDGYGPSIHVPPARALELWGYPV
DDKDLSKLFADTIVGKLPFMPWSDQTLSPETMLIQEQLMELNQKGIWTVASQPACNALKS
DDNIFGWGPKGGYVFQKSFAEFFISPEQWKKLKPLLDAQEDLVSYYVAKSDQCVDTNVAE
RASNGVTWGVFPNREIVQTTIIQEDSFDAWREEAFSIWSEWRALYKKNTASFKLLDKIIN
EYLLVTVIHHDYVEEDALWELLGSV
>A0A7K6KBS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oreocharis arfaki|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A241NJK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio anguillarum|TrEMBL
MGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSAQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHLIIKEIKEQTGLIAAPHLTCIDASRDELIQIADDYWHNGIQNIVALRGD
IPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQSDLVNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFN
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A164CWD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces sp. NDB4Y10|TrEMBL
MTGTGPDDGDRRPRPPISFELFPPRTDAAALALGRTIDRLAEVDPVFISVTFGAGGSSRD
RSLTVLRYMLEHTDVEPMAHLTCVGSSHAEANRLVREFLDAGVTSFLALRGDPPAGAGPD
TGLGDLRSAAELVQLIHRVQEEREPFGQVGIPGIPGATRILDRPRPERVAVAAFPTGHPR
SRGIGQDVDVLLAKEVAGANLAITQLFWHADDYFGFVERARAGGVTIPILPGIMPVTTPG
RLSRLQELTGVPAPSELAIPLEIEPDADALFDLGVDFAADLAREVLDGGAPGLHLYTFNR
HEAVLAVLDRLGIRTPAHAGTERNTRER
>A0A2N3XWZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora spinosa|TrEMBL
MRFRARMCANRRQAAPERAACSNRHVAPVVGRFTILFGMTAVVDRLNTEKTTFSVEFFPP
RSDDEERILWRAVRELEPLDPAFVSVTYGAGGSSRDRTIRTTGRIAQETTLTPMAHLTAV
DHSVAELRNVIGWYAASGVQNVLAVRGDPPGDPNGEWRQHPEGLTYAEELVRLVRELGEF
CVGVAAFPHGHPRSTDLDIDADHLVRKIRAGAGFAIAQLFLEPEYFLRLRDRMVARGCDV
PLLPGVMPITTPRVLGKFGELAGVPVPAEVSEQLMPLAEDPAGFRAAGVDLVTRLCERLI
AEGVAALHFYTLNRSKATRQVVANLGL
>A0A0S8CZY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira bacterium SG8_3|TrEMBL
VHDIDSIQLIQTVRHMRDEGKFLGGDDLDGRPQMFVGAAANPFADPFEIRVPRLAKKVAA
GVEFIQTQCIYNLDKFEEWMKGVRDRGLHEKCYILAGLTPMKSVGMAKYMQKRVPGMDVP
DEVIQRLQGVEKGKQAEEGIKICIESIQRLKECEGVAGFHVMAIEWEEKVPEIVEGAGRS
>T0RGF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprolegnia diclina (strain VS20)|TrEMBL
MGKIIDRLLELEKTGTPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSGFK
DEKLWLKIGAHIQNEFKIDVLMHLTCHLPQDQLRVILQNARNAGIRNILALRGDPPIGAE
RWKAVPGGFRNAVELIRFIRQEHGDYFCVAAAGYSEVHTEAWNNPNLPPSDQVRNLDMLR
LKEKQDAGADFIITQFFFDVDKLSQWIRDCRAVGIRVPILPGYLPIQNYNSFLKFTNWCK
TSVPDHVVQALNSIKNDDAAVKKYGIQLAIETCRKLMSQQLSLHFYTMNLASSVRSVLEG
LNLIPRRHERDLPWGLPMLRRKEGSADKIEQVRPIFWSNRASSYVARTSEWDDFPNGRWG
DRSSPAYGELSEYYLAYKRPKVARERVWGTPLTEQDVWSVFVKFIEGSVKTLPWCEQGLS
GESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKGGFVFQKAYVEFFVPPHL
MERLLVALKDYPNLSYHAFSANGTEYTNAPGPSVTAVTWGVFPGQEIIQPTVVDSASFAA
WKDEAFELWMSQWASAYASDSVSHSVIKEVYESYVLVNIVDHDYTNEDSDIFKIFARVIT
EGMTKDDLRGRVLELEEKNEKLHETVAKLKIIQSEASRELKEVHQELSASREENNRLKTQ
LRELRARAALSAI
>A0A2H3HK59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. radicis-cucumerinum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDRIKAIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>R7KIZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides thetaiotaomicron CAG:40|TrEMBL
MRVIDLIHNSEKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLFWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEVLKCKNDKEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A3R6U313|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM05-9|TrEMBL
MKIRDIIGQEKATLSFEVFPPKKDTDFASVEAAALGIAALRPSYMSVTYGAGGSTKGHTI
KLANEIQEKYGVPTIAHLTCVCANKDSIRTALSEMKNAGIENILALRGDIPKNYDGQVFT
DFAHASELVKLIKESGDFCVGGACYPEVHPDSANKQDDIANLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRIREAGIAVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEVAAGIQANLSDILLV
>A0A2R4JNI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. P3|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFYAPKTPQGERSLWNALRRVEAVAPDFVSV
TYGAGGSTRATTVRETEQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSDAWETDVAHFVD
KCRAGADYAITQMFFEPDSYLRLRDRVEAAGCVTPVIPEVLPVTSVKMLERLPQLSNARF
PAALKERILTAKDDPSAVRSIGIDFATEFCARLLAEGVPGLHFITLNSSTATLEIYENLG
LHHPPQA
>A0A7X0Y5Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria grandensis|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADVIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGIHGANDARISAPDM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITREATDLPIVANVSMHEPGLL
QSGQTLASALQELADLGADVVGANCRLGPYHMAKALETVPILDNAYLAAYPNASLPQMEE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLQSTEPVTAKAVHPIL
ELAELEVAEDVGVRLTDKVKDQFTVLVELDPPRTFDTAKFFEGAKELDEAGVDAITISDN
SLATPRISNMALAAILKHEYDIRPLIHLTTRDHNLIGMHSHIMGFHKLGIQDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALVEAGITVPVFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREADKNGTGREEGMAIAKEIIDAICEHFNGVYIITPFLRYDLSIE
LTKYVQSKQQVVEVSSQN
>A0A8E2T3S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. AU31280|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DTRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAAVATRTICERLAV
>A0A158RLJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus (strain 03BB102)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7W6DIN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium fontiphilum|TrEMBL
MTQSNEAPWFADLAGDIRVSFEFFPPKTEKMEEQLWSAIGTLTPLAPQFVSVTYGAGGST
RERTHNTVARIARETPLAAAAHLTCVAASKDEIAAVADAYWEAGVRHIVALRGDPPQAGE
RFQPHPQGYQGAADLVQGLAKRHPFEISVAAYPEIHPEAASAQSDIDNLKRKLDAGATRA
ITQFFFEPDCFFRFRDTAAAAGIDAEIIPGIMPVSNFAAVQRMSAMCNTSVPNWMGRLFD
GLDDHPAARQLVSATLAAELCRKLYAGGVRDLHFYTLNRAELSYAICHMLGLRPKAQAEV
AA
>A0A3U4AKI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRNSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6S7PB34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactuca saligna|TrEMBL
MKVIEKILESTAAGDAGKVVFSFEFFPPKTEEGVENLFERMERMVAHNPTFCDITWGAGG
STAELTLEIARRMQNMVCVETMMHLTCTNMPVEKIDHALETIKKDGIQNVLALRGDPPRG
QDKFVQIQGGFACALDLVEHIRKSYDDYFGIAVAGYPEAHPEVIEGNGLATPEAYQKDLA
YLKRKVDAGADVIVTQLFYDVDNFLKFVNDCRQIGITCPIVPGIMPINNYNGFIRMTGFC
KTKIPSEITAALEPIKDNEEAVRNYGVHLGTEMCKKIMASGIKTLHLYTLNNEKSALAIL
TSLGLVDEAKITRPLPWRRPTNLFRLKEDVRPIFWANRPKSYISRTGGWEQYPHGRWADS
SNASYGALTDHQFMRPRARDKKIQAEWVVPLTKFDDISEKFMKYCLGQLKTSPWSDLDAL
QPETKIINEELASINLKGFLTINSQPAVNGAKSDSPSVGWGPAGGYVYQKAYVEFFCSGE
KLNALVEKSKAIPSLTYLAVNKEGTLVSNVGKNDVNAVTWGAFPGKEIIQPTVVDPASFL
IWKDEAFEIWSRGWAQLYPQEDNSSRSLLQEVQNTYYLVSLVDNDYINTNLFTVFKGF
>A0A4V0X2J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MKKIINKLEEIALNQKELNVSFEFFPPKNDEMEEKMWQAISSLRTLNPSFVSVTYGAGGS
TRERTHHTISKIIKETTLKPASHLTCVGASKQEIFEILHNYWQIGVRHIVALRGDMPASS
PNYQLHPNGFKYANELVKGIKDLDKEGINFEISVAGYPEKHPEAKSLEEDIDNLKRKIDA
GANRIITQFFFDTDVFLRFIDKCQKAKINVPIVPGILPVTNVKQAKHFAKMCGTNIPKWM
DQMFEGLDEKQDTRHLVAGIVATELCRILHRSGIDDFHFYTLNRSELTLAICHVLGVRET
NISSLEN
>A0A2E5Z3V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MRIKLGHLSNIQGTEVYLSKGSFIEKESISVSFEFFPTSSEKLEKQLWESVLLLAPLKPS
FVSVTYGAGGNTRQRTFNTVKRIVTETPLIPAAHLTCIGSTSESLQVAAKEYWDVGVRHL
VALRGDPEQKTGKFVPHPKGYKNAGELVRGLKEVADFEISVAAYPEVHPEAQSADSDLDN
LAYKLDCGASRAITQFFFDIDVFLRFRDAATARGINAPIVPGILPVTXIKRLIQFANHCK
TSIPNWLKDMLNGLDKDPNSRRLIAGWIAXEQCRQLARHGVTEFHFYTLNRAELTRAICH
ALGVRDQERLEST
>A0A537NIN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MVQQAQFHASRSAGVAGQCRIRVSFEFFPPKTEEMDKTLWESVQRLAPLAPSFVSVTYGA
GGSTRERTHATVKRILAETALVPAAHLTCVAAKCAEIDAVVRAYCEAGVGHIVALRGDPP
GGAGERYAPHPGGYANAAALVAGIRKIAAVEISVAAYPEKHPDSSTVEADLDMLQAKVDA
GADRAMTQFFFDNDHYFRYLDRVRARGIDIPIVPGILPVQNFKQAKTFAERCGASVPRWL
AERFDGLDDDPATRKLIAAAVAAEQVLDLVDRGVSDFHFYTMNRADLVYAICHLLGLRPH
AAPMRTFIRGASVALLPLPAGERVGVRGFGRKMERNSLNERERQSFDSEAVAQESN
>A0A0Q5J7T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. Leaf148|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTATKLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFESAPHLSCVGGNRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAVDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ASLCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A2A4VAX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSKATFSFEFFPPKTDKTTELLFKAIEDLKALNPKFMTVTYGAGGSTRDKTLQIIKRVIA
NTDIPTASHLTYINSPRKEMYALADELWENGVHHIVALRGDMPADLEWPLDPDAEYFQYT
SHFVAALKARQDFEISVGAYPEKHPDADSIDKDVEALMKKIDAGANRAITQFFFDNTVYY
EFLEHCAKANIKAPIVPGLLPIHDFKSMCGFAGRCQASVPKWLHERFEGLEDKPEDARKV
ALDLLVGQSEDLVKNGVEHIHYYTLNKSDITTQAVEAIS
>A0A379UYC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MSNFKQAKKFADMTNVRIPSWMSLMFEGLDDDAETRKLVGANIAMDMVKILSREGVKDFH
FYTLNRAEMSYAICHTLGVRPGL
>A0A1Y2EJ70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomassariella vexata|TrEMBL
MMEKITDKIAALPADANYFSLEFFPPKTGMGFSNLRDRLDRMARALRPLFVNVTWGAGGS
TATKSLELAEICQRELNLTTCLHLTCTNMSRKLIDRALEDAKALGVRNILALRGDPPRAA
EYRDPNEQPEDAIDESFVWAIDLVRYIKKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHD
LPYLVEKTQAGADFLMTQLFFDTQAYDNFEKVLREHPSGAFKTIPIIPGLMPIQSYQMIK
RTTKLSHARIPDALMARLDDVKKDDEKVKSVGVEILCEIVEQVKEIKSRTNGPKGFHFYT
LNLEKAVSFIVERTNLILPEATGEEEAVADDDMQIVPTVTINGSSHQEHLTSLHDSSRRQ
SSIGSDPRNRVIVSGRPPSHPEYEATATQASIPAEPINTRANTLAISEGEGTLGREATWD
DFPNGRWGDARSPAYGEIDGYGPSLHMTNVQAVGLWGYPKRFEDISDLFIRHIKGELNAI
PWSEEEFNAETGTISPLLLRLNSKGWWTVASQPAVNGLRSSDPTFGWGPENGFIFQKAFV
EFFIPSADWKVLLEKLQSSEYQGTVCFYASNAASDFVSSDDTGGLSGEKKPASTNAVTWG
VFPGKEIITPTIIEEVSFRAWSEEAFGIFGEWAKVYDKGSESSRLLEGIKADSWLVNIIH
HDYVDKDGLWDLLLG
>A0A2W4X2U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MVRSVWRSQAESDDARAQAQGRAYRENLGWREAVSLAQDIIASAAPRNGRPRVSFEFFPP
KSEALEGQLWESIRKLEALGPSFVSVTYGAGGSTRDRTHRTVARIVSETTLKPAAHLTCV
AASRDEVDAVLRDYWRAGVRKIVALRGDPPGGVGMPYLQHPRGYASAIDLVEAASRVGAF
DISVAVHPEKHPSSPTFEHDIDNFKRKLAAGATRGISQFFFDETVFLRFRDRLARAGVYA
PVLPGIMPVTNVKGLRKMVDACGASLPRWMVKLCEGLDDDPETRRLVAAVTTAQLCARLA
AEGIEDFHFYTLNRADLTLAICRILGVRAQQVTA
>A0A1Z4SWJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix sp. NIES-4105|TrEMBL
MLIVMLDTLTPITPVKVSSFRAAARDGEFLVTAEVCPPKGGNPQHMLQMAATLKGRVHAV
NITDGSRAVLRMSPLVASIILHQNGIEPICQFACRDRNRIGLQADLMGAHALGIQNILAL
TGDPVKAGDHPDCKAVFDLEAVRLLQVIQKLNLGVDYNDKPLTDGALDLFCGAAIDPQCK
SWSGLQSRFEKKVAAGAQFFQSQLITDFERLEKFMDTIAAGCNKPILAGIFLLKSAKNAE
FINRVVPGVNIPTHIIDRLAQAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIAP
ILDMAGVAAVK
>F9T1F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio tubiashii ATCC 19109|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELVRIADDYWANGIQSIVALRGD
IPPGGGKPEMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A2W4UF09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTANLDTVAEAARALNPSLYADLPGDIAVSFEFFPPKTAAMEATLWESVETLKPLAPRFV
SVTYGAGGSTRERTHSTVARIARETQIPAAAHLTCVDASRAEIDAVADAYWQAGVRHIVA
LRGDPPAKDARFAPHPDGYATAADLVAGLKRVHDFEVSVSAYPEVHPEARDAAADLDAFK
SKLDAGATRGITQFFFEPETFFRFRDRAAAAGISAEIVPGILPVTNFANLQRMAGPCGTA
VPAWMARLFEGLDDKPAARQLVAASVAAEQCRRLYAGGVRHFHFYTLNRAELAYAICHML
GVRPVAAPLEIAA
>A0A5B8MAC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Humibacter sp. WJ7-1|TrEMBL
MPCPRGTPFSFELYPPRNEAAAKALPETLQRLAAVGPDFMAVTYGAGGSSHASSLNVVKQ
ILSDTTVPVMAHLTCIGSSHEEAGRMIREFLAAGVTRFLAVRGDLPADSPPDAPLGDLHS
AAELVQLIHRIQAEREPYREIPVPGLPRARAVGRREKVTIAVGAFPNGHPSSRSTTQDID
TLLAKQASGANLAITQMFFHAEDYFAFVDRARSAGVTFPILPGIMPATTPGVLRRMLELS
GEDLPAELGIQLEVEPTDEGRREIGIDYAARLASRLVAGGAPGIHLYTYGRPQTALAVLE
RCGLIDQQHLTTSNQKDYA
>X5YTR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNJC399B00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A316GX72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter sp. AP02|TrEMBL
MTPPRPRQTDEHPDGIDLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQ
LFLGAAVNPFAPPYDFRPVHMGKKIAAGAQFVQSQYCFDVPMFRTFMNRVRDLGYDEKCF
ILVGVGPLASAKTARWIRANVPGIHIPDSIIKRLEGAQDQKKEGKQLCIDIINEVKEIAG
VSGVHVMAYRQEEYVAEIVDESGVLKGRRPWKREARADDQRVAERLEHILHDNVTETQVD
MVKTAH
>A0A844XG40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantiacibacter rhizosphaerae|TrEMBL
MSYAAIHPNWEKPMGNMVDGYSLEMTAKEIDGLREAAPLIRPDTQIAVTFLPGEEIEQRI
EASCVVRELGFEPIAHVSARRIKSHEELDYYLRETAQRAQAKRIFVIAGDPPEPEGPFED
SLQIIETGLLEKYGYEVIGVGGHPEGHPNVSRDDLWVWMQRKLDAITAHGMVPLVVTQFA
FDDDAIVEWLADMRERGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGVSITN
LVGKAGPDKLVGNLEEKLTERHGRVRLHFYPFGALTASAEWINDYDARHQ
>A0A7C4TA84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MVAEATTREARAGGRLEWVLNRGEFAVTAEIAPPASADPDAVRRVAAMYRDVADACNVTD
CQRALVKMSSLAASVLVMQEGVEPIMQMVLRDRNRIALQADLLGAASLGIRNVLCLRGDD
PRAGNEKEAAGVFDLTTEDMITTFRNLREKGILRGGELVEYPPRVLIGAAANPFAGSPEE
SFANLRGKVMAGADFIQTQAIYDVDAFEEWMRLVRKEWLHDRVHILAGVIPLRSLKMAKF
MAEKVPGIAIPKDIMERIASAPDPKAEGISIALRTIKALRKVEGVRGVHIMAVNWEDVVP
TLVKDAGLLPRPTMAAISS
>A0A182RSN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles funestus|TrEMBL
MAASTTNSVNNELLHTKLDRIFNSPAETVIPVQYSIEIAAKEDFNIGELERLTPQPVFCA
LPWILDDNLRYADDFLRAPTLQLTGQLRNAQYTVVNHVSCYNITEQQVERLLSAGIQNLF
VIRGDTVQRDQKFQHSAELVQFLQQQQPDRPKLTIGVGGYPYGHHQSPSKTEELRYLKEK
IDHGVDFLLTQTLYDAESFFRYREQCRTAGIRIPIIPGIYVPYSYRHLRAMLNLTRITLP
PALDAVFAAHANDDPEQFEAFAVEHFVGVLGELLKPNVTSNDPIKLVHFFSFNKFALVQK
VLQKLNDFFY
>A0A7C5FG90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MTGQASEPSYLQKKLCENRFVVTAELGPPKGADPEYVRERARILKGYADAVNVTDNQRAV
VRLSSLASSLIMMQEGLEPIMQMTCRDRNRIALQSDLLG
>A0A519D5G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MRLRDKITKAKRPVVVYEILPPRIVDGTIESYAEQISTLLSKTHIDAINIPEVHAEESRG
ERPIEDRERASPRDFGRLIQDSVGVEAIVNRVTVRETPNDQREWFRVTSDEFGIDNIILV
GGESSQIEYPGPGVAESAIMVSEINHEIEGEIFCGGIVLPSRKVESKRMERKADNGVQFF
TTQVLYDSNDICKLLWHYNKSNQERDTEPKRVLLSFAPISTKKNLNFLKWLGVEIPEDTE
KFLIQDEELIKERSIQICMDLLEEILAFVTENKIRVPIGVNVEHIMTYNFEHSVELLQRI
SKKYRSFCMETDLYDT
>A0A2E3DEX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MKSKLQETLESNSKVITAELMPPRGGDPVRSLKIAQLLKDKIHAVNITDGSRAVMRMCSL
AMSKLLLENGIEPIMQISCRDRNKIGLQSDILGANALGIKNILCITGDSVKAGDQKDAKA
VHEFESVRLLKQIQDFNNGYDPSYEFLIDKKTNIFAGAAADPSCKNRRILKMRTEKKKEA
GANFLQTQMIMDKQYLIDFCREITEPLRLPVIAGVFLLKSYKNALFINKYVPGARIPDNI
LKRLKDSKEPLNEGINIASEQVRDFIKIGQGVHIMAVKCEELIPEIIKRSEVNLEY
>A0A844XGT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantiacibacter rhizosphaerae|TrEMBL
MNSFTPSTNAADTPGSIAAMPGDIAVSFEYFPPATSKAENLLARTSQRLSAFAPSFVSMT
YGAGGSTRERSLAAIRKLVDEGSAPVAAHLTCVDASRDQVDDMAMQFHASGIRHIVALRG
DGGEPGQPFTAHPQGYANAAELVAGLRKLADFEISVAAYPEVHPDAQSAQHDLDNLKRKL
DAGATRAITQFFFSADACLRFRDRAVAAGIDAPIVPGILPITNFAQTCKFAGACGAQIPA
PMKAVFEGLDDHPETRKAVSIATTAELCRKLYEGGMREFHFYTLNRAEQIEAICHLMGLR
VPARVEAAA
>A0A1W9UCB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium 4572_32.1|TrEMBL
MIAGSNLEKVLRAGHFAVTGELGPPTDANAEVIKEKAQHLKGNVDSVNITDNQTAVVRMS
SISVAVMLMEMGIEPNIQMTARDRNRIAIQADLLGAWALGVKNLL
>A0A5R8MCW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas urmiana|TrEMBL
MNDLCSAMPPEQRLRGCLALARSRYELLPLADLQEAAHRLPPGAWVTVTCSPRHGIERTL
EAAERLSRDGFCVVPHLAARLVRDHDHLEAIAARLSAAGIDDAFVVGGDAPRPAGDYANG
LALLEALSQLPGRPARLGVPAYPEGHRQLDGALLQRDLEAKARIADYAVTQMCFESAPLL
DWLRRQRAGGLALPVYAGIPGVIAHARLLSVALRIGLGPSTRALGRQRGLLGRLLRPAVY
RPEGLMRGLWPSLEEPGGFAGLHVYSFNQVSATRAWLEALCASYCAGQALEPALSSSADS
GAEIVKPAARC
>A0A366ZYZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus sp. TF02-6|TrEMBL
MNRAITVREPAARASLKKVFATLGYEVIPFKKTEEAVLAHVPKDVRLTVTASPAKGQDAT
VDLTVRLVGHGYTVAPHLSAQQVRDRAHLADIVARCREAGVTDVFVVGGDPSDTPTEFEN
AHDLLVALHELPHGFTDIGIGGHPEGHPAVDDEVLLQALREKAALATHITTQIVFDPKVI
LAWARELKRHGIDLPVHVGVPGAVHRQKLLRVSGGLGVGESAKFLKKQQSMFWRFFVPGG
YSPDKIIKGLAPHIGKPDNGIEGFHVFTFNDLGPTEAWRRRTLQGLA
>A0A366GD34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter marplatensis|TrEMBL
MPLIHPSSPQSPGHITDAYSLEVSAKDIPALTAAAPRMLPGSTISIPYLPGQDDNARLAA
ARAVRALGLVAMPHLSARRIASLAELESFVTRAVAEAGIERCFVIAGDPSTPLGPFADSS
SLIETGVFERAGIQVVGVGGHPEGHPVMSAADRWEVLERKCRSIGMRGMTPLIVTQFGFD
ADIVLAWLKTLRERGIEHPVRVGVPGPAGIAVLARYAALCGVSACASMWSKYGISLGKLF
GTAGPDVFVDRLVAGLTEEHGEVSLHFFPFGGIAQSVKWIAQYRAQGQ
>A0A0A2Y7Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallibacterium anatis IPDH697-78|TrEMBL
MSYAKEIDVLNRSIADLNGDINVSFEFFPPKNEKMETLLWDSIQRLKSLQPKFVSVTYGA
NSGERERTHSVVKAIKQQTGIEAAPHLTGIDASPEQLKAIAKDYWDSGIRNIVALRGDEP
PGYDKKPFYAKDLVKLLKEVADFDISVAAYPEVHPEAKSAQADLIFLKQKVEAGASRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFVQLQKMAKVTNVKIPSWMFKLYDGL
EKDQTTRNLIGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGVRPSLAA
>A0A4T0ITK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia ichthyophaga|TrEMBL
MADNLEHPDHGKDTPYFAYYAALVNQANMLMDSARTGVYQQSILGNSQTAFLGKDVLDVG
AGSGILSFFSAQAGAKTVYACEASDIASKLQLIVDEADNGGKNAFLKDKIKVVKSKIEDA
ATSHSIPKKVDTIVSEPIGVLLVHERMIESFIEARDKFLKPGGSMFPSSGTIELAPFTDD
ALYTETAQKSGFFQQTNFLGVDLSVLQDAANEEAFSQPVVGMFPPNQLIANTTNNHLIDF
YTCSMNDLTSFTIPFTWQITRTALLHGIGGWFDLHFKATQAGGLDLYLSTGPTAPRTHWQ
ATRLLFREPLAVNAGEVVKGELKFSVNDQRSYDIVGTTEIQTSKEFYTAQHPQSFVSCIQ
TIIIFMSLRDRQRKNIENILNFNDNKKSSDLVWKVLVLDGVSKDVLSTAVKVQDLREQGV
TLHAFLHNERPQMSDVPAIYFVEPSVDNMKRIAADVGNSLYESFYINFTSHIPKHLLEQL
ASSIAQTGREDLVKQVYDQYLDYVVLSPTLFSLLPSSSTPSFQILNHPSSSEEIIEAEVD
RISQSLFSVLGTVGSVPIIRCPRGNASEMVARKLDERLRDHLLSTRNSSLFNEDRSLQRP
LLILFDRTLDLIPMFSHSWTYQALIGDVLDLKLNRVKVETPENGKLSKKSYDLDYKDFFW
SKNAPNPFPQVAEEIDAELTKYKYDASEITKSTGVSDVKDISQVDFSSNAANLKSAITAL
PELTARKTTLDSHMNIATSLLTAIKTRGLDTLFQTEEVAARQSKNQILDVLKEVDGATPD
DKLRLIIIWYLSVPSPNSADVAELERYLADKGIDLKPFSYIKQARQVSRMTSLTAAASTV
AAAPTNGGSDLFKGFSSISNRLTDRLREGGVGFDNILSGVKNFLPAKKELAITRLTEALM
DPYNCSSQASQDVDDYLYFDPKQSRSTYGQKPRQQGGHKQSFDESLVFVVGGASLVEHAN
LVEWATRPQQTQKKLSFPPKTEQGFVNLKSRLQRLSLLNPGFISVTWGAGGSTDERSLEL
AATARSLGLDVLLHLTCTNMHKNRIDSALDRAKQLGIDSILALRGDPPRGHEYWIETDAA
FRHSSDLVHYIRQRHGDSFCIGVAAYPECHKDSSSAAQDLNYLKLKQDLGADFIITQLFY
DSDAFLNWLDKCATNGIEIPIIPGIMPIQNVPSLRRLANLCGAHIPSVISDHLEPIKNDD
ALVKDYGVELSTSMVRQLIDKTNSEKDKYRHLSLHATHFCTLNLEKSVRRILANLGWSAG
LDSSSLEPNGLTNKNSDALERARLGNRLVAENGSTGHDTSGAPPQLSITAHEAAVRALHA
LKHHPPSEDSGLPSSNKTSSGGNSLWDEFPNGRYGDIRSPAYGELDGWGASLKTSSQNAL
RQWGYPLQTSDINEIFKKYINGDISCLPWFEENLDPESNSIKDYLFKLAEKGWWTVGSQP
AVDAIESSDAVFGFGPKNGWIFQKAFVEFWVPDHQLEPLCKRLDGWKDGGYYAGNAKGEM
RSNFYEDTINAVTWGIFPGQEVVQTTIIEDVSFNAWREEAFDIWLEWSMLYSPKSASQQL
MKNVHDNYWLVSVVHHDYKDTYGLWDFLLS
>A0A847ZVB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacteriaceae bacterium|TrEMBL
MTAALRVSFEFSPPKAGDGEESFWSTVKRLETIGPDFVSVTYGA
>A0A178DA15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fonsecaea nubica|TrEMBL
MASEHDDRLPTLLSSLQPSSYYFSLEFFPPKTSSGFSNLQARLARMATALRPLFVTVTWG
AGGSTATKSLELAEVCQRQIGLTTVLHLTCTNMKRNMIDEALEGAKEIGIRNILALRGDP
PREEYKDATSTDDSESGSGGSGTESNQEFTWAVDLVRYIRRKHGDYFAVGVAGYPEGHAD
ESHPEQGKQSVEHDLPYLAEKVAAGADFIMTQLTYDIAAYAAYEKRLRGYADQDGKRLFE
KIPIIPGLMPIQSYQIIKRITKLSHAKLPEDISQRIERVKSDDEAVKKVGVDILSELVEE
MKTLTQPEGLPRGFHFYTLNLEKSVSFILERTGLIPTISSEGSVEDKDGDSASDSDVVVD
DSKQSTPAIVTTGPGEDRHEEQPSGFVRRRRSSVNAQPHNRVITDRRSEPRTESRRPDSD
TDPPGLGPSPNLKLTSQHLATDRGTGIPAASPTRQHSLLISEGQGSLGREATWDDFPNGR
WGPSHSPAFGEIDGYGPSLKVSPLMARKLWGYPRSRQDVTELFRRHVLGELAAVPWSDDI
DPDLVSPGGGSADGSTNSSALRAETDVIRAELISLISRQNYWTLASQPAVDGAPSSDPVF
GWGPPGEGFVFQKAFVEFFCGRDEWEDKLRPRLIKHGSDVLGWMKTDAEGLFESSELVAR
DQARNQKTRAAADTEKENSKPASVSQGADQKVATSTSTSSPTNTVNAVTWGVFPSREILT
PTIIEAESFRAWAQEAYAIWNEWKRCFPRGSPESVFLEKMGKDNVLVNVVGQGFRGGHNG
GKGEGGRLWRILLGEDGDDKT
>A0A7X5TFV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus cinerea|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTVEMEKTLWKSIGRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELRKIARDYWNNGIRHIVALRGD
LPDNSEKPKMYGVDLVELLKEEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQLQRFAVMTNVRIPSWMTRMFD
GLDYDPESSNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A6N9TRZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dissulfurirhabdus thermomarina|TrEMBL
MIAGSNLEQVLASGQFAVTGELGPPKNGDPEVVRQKARILKGHVDAVNITDCQTAIVRMS
SLTAGLIALSEGVEPVMQMTCRDRNRIGMQSDILGAAALGIRNLLCLTGDHQKFGNHPQA
KGVFDMDSIQLLGMVRRMRDERRFQCGEEIKGGEPRLFLGAAANPFADPFEYRPIRLGKK
VAAGADFIQTQIIYNVEKFARFMERVRDLGLHEKVYILAGVTPPKSVGMANYMKKFVPGL
DVTDEVIQRMRAARDKQEEGIDICVDIIRQVREIPGVAGVHIMAIEWEQAVPEIVKRAGL
DPRPAPKGVEAVLGGAAALEAAEKARQEAEAASVHVLREKDRLAAEVSGLRSELEAARGR
AEKGEAEVRRLLAELEAAKAALAAGGAAPALAGAATMTPEGGESMAEKMDRERRALTSLS
QGLQALRKVMGLSEEQFEALRRFIEAEFYLSTGIAAGTLPAAAAAIPVER
>A0A2S8AGB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apibacter adventoris|TrEMBL
MKVTEHIEKAKGKTLFSFEILPPKKGDNLQTIFSNIDPLMEFNPPFIDVTYHREEYEYKE
LSNGLLEKIIIRKRPGTVGICAALQLKYKVDAVPHLICGGFSKEDTEDILIDLNFLGIDN
VLVLRGDAIKSEGIFRPHPNGYKYANELVEHVTAMNKGKYLHDEYASGATNFCIGVAGYP
EKHFECPNLDTDLHYLKKKINAGAKYIVTQLFYNNQKYFDFVDKCRNIGITVPIIPGIKP
ISIKNHLTVLPNVFHIDMPQDLVLEVEKCKNNKEVYEVGIEWSIQQCKELMKHNVPVLHF
YSMGRSKNILKIAKELF
>E9CLY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia symbiotica str. Tucson|TrEMBL
MSFYHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIHRLSSLKPKFVSVTY
GANSGERERTHSIIKGIKDRTGLDAAPHLTCIDASPAQLRDIASDYWSSGIRHIVALRGD
LPPTDGGRPEMYATDLVTLLKDIGDFDISVAAYPEVHPEVHPEAKSAQADLINLKRKVDA
GANRAITQFFFDVESYLRFRDRCVTTGIDVEIVPGMLPVSNFKQLQRFASLTNVRVPSWM
TSMFAGLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPM
AAA
>A0A379L564|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREHHFVCVMEFVPKASAERFAAMQAIMDRVQLCGWPMTVAIGDRVGSPLDMS
PLDALASFDRPVPALPHFSGKDRERHHLLAQLQRMAAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQAAPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMREMLEAETAHSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGIHDLKQLLALEARLAYWQTHVHTLEQWAPA
WQASWQMPGLPAVTFHPPQANWRQGESRVDASFKEKARYHLMHGMHGLLFSRRNSLSKAF
GWAVRQPLWTTRLGAQVLHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVGQTAVLRERLIPCIEEQTRHRSSWPQWFAPPSP
RRVSPQPAPRTQPES
>A0A855XEY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limosilactobacillus reuteri|TrEMBL
MTTLSYEVFPPNSQVGNDHLTQTLAELKGLNSEFISVTCSSKATNLAQETVRVADYIQNQ
CGVPAMAHLPAWYLSKNDVDQIIDNLRERHVSHVLVLRGDERPNLEKKNDFSHASDLISY
IHDNYSDFQITGACYPEMHPESLNMVEEIQHLKLKVDAGCDQIITQLFLNNHCYYQFREL
CAIAGIDVPIITGIMPVINERQANRILKTSAVNVPEKFTNILAKYANHPQALKQAGITYA
IDQIVDLVTNDVAGIHLYTMNQADTARQIKNNIGSLFEVASAC
>A0A6B3EIQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID11233|TrEMBL
SRLSTASFPETVKERMLAAKDDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTAT
LEIHENLGLPHHRP
>A0A1X1A6X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMAVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDELRTLINQYKAAGIKRIVALRGDLPSGMGMAYGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQARNFESDLANFVHKVKAGADSAITQYFFNADSYFY
FVERARKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDYTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A3JZU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sagittula stellata E-37|TrEMBL
MTRPDISLEFFPPKNIEGTFRLWDSVQVLAPLKPRFVSVTYGAGGTTRDLTRDVVATIHK
HSGLRTAAHLTCVDATREETLQVARDFAKVGVSDIVALRGDPPKGSAGFEPHPEGFANSV
ELIEALADEGDFTIRVGAYPDIHPEAASGQADIDWLKRKLDAGASEALTQFFFEADTFFR
FRDACAKAGIDKYVTPGILPIENWKGARRFAEACGTKIPAWVIDAFEKAERDNRTDLLAT
AICTELCDDLIRGGVDKLHFYTLNRPELTRDVCFALGVTPEIKLEEVA
>B9KNR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cereibacter sphaeroides (strain KD131 / KCTC 12085)|TrEMBL
MARPRISFEFFPPQTLEASFRLWETAQMLAPLKPDFVSVTYGAGGTTRKLTHDAVETIHT
HYKLNVAAHLTCVDATKAETLEIAASYAEAGVTEIVALRGDAPKGSDRFTPHPEGFASSV
ELVEALAATGRFKLRVGAYPEPHPDAADTLADVRWLKRKIEAGATSAITQFFFEAETFLR
FRDLCAKEGITAPIIPGILPIENWSGVKKFAARCGAQVPGWLDDAFDHARRDGREELFSV
ALCTELCDRLLSEGVEDLHFYTLNRPTLTREVCHALGILPEVALQNVA
>A0A2R7NI83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. HMWF028|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGYQYFEPTQGGHPSAMDLVNQINNLGRGKYLHNEEQTCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A4S1A2P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.156.01.1.1|TrEMBL
MNARQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPVHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWQREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>K0NCN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula toluolica (strain DSM 7467 / Tol2)|TrEMBL
MSELKSGSNLEKVLNAGHFAFTGECGPPKGANVDHLNEKLSHLVGYVDAVNMTDNQTAVV
RMSSIAGSVLMMEKGLEPNFQMVCRDRNRLAMMSDILGAYAMGIRNMLCLSGDHTSFGNH
PEAKGVHDIDSMQLIAMVKKMRDEGKFLNGEDIDVPPKLFIGAAANPFADPYEYRVFRLA
NKIKAGVDFVQTQCIFNMEKFRDFMKQAVDMGLHEKCYILAGVTPMKSAPMANFMSKFVP
GMDIPEHLIKRLRGVPKKDQPEEGIKFALEQIEEFKEMEGVAGVHLMAIEWEHRVPEIAE
RANVLPRPVVE
>A0A083UMU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLSQYKAAGIQRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>D3E5S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. (strain Y412MC10)|TrEMBL
MKPNLRQAWENQVLVGDGAMGTYLYQKGFPVGISYEELNLTSPEVIGNVHRQYVEAGAQV
IETNTFSANYDKLSKYGLEARVGEINRAGVRIAREAAGDQGYVVGAVGSIRAGKRSNIST
SELKRYFEEQLSVLISEGVDGILLETFYDVDEMQLALAQARMLSDLPVICQFAVEDIART
LDGFTMPDAYRILSHEGADVIGFNCRTGPNGIMRALETLNGIMNLPASVYPNAGIADYVD
GEYRYGASPEYFGKTALEFADRGARIIGGCCGTTPEHIAEISSALSGYVPSPLPAVEEAE
INRIVIHETAQEQFYERSGEPTIVDIVKERHTVIVELDPPRDLDITKFMKGAEALKKAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVVGAAFNP
NVRHLDKAVARLEKKIASGADYVMTQPVYDPELMVRLREATAHLDIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAMGVKIGKELLDVATEHFNGIYLMTPFMFY
EMSVQLMEYVWEKSGRRLTPLFH
>A0A7K2FSV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4985|TrEMBL
MALGTASTRTDRARTVRDILATGKTAYSFEFYAPKTPKGERNLWDALRRVEAVAPDFVSV
TYGAGGSTRATTVKETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPRGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSTDWDTDVSHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEILPVTSVRMLERLPKLSNAVF
PSELKERILAAKDDPAAVRSLGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A849DUM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dactylosporangium sp|TrEMBL
MTFGAPRRPAAIGDLVRGPAPTFSFEFFPPKTAAAEHLLWQTIRELEPLHPSFVSVTYGA
GGSTRDGTIAVTERIATETTLLPLAHLTIVGHSVAELRNVIGRYAAVGVRNVLALRGDPP
GDPNGAWIPSPGGLVYADALVRLIKESGDFSVGVAAFPEKHPRSPDLETDVARLVGKYRA
GADFAITQFFFHWEHWVRLRDAVAAQGCDMPIIPGLMPVTNVRQIQRMTELSGAAFPQDL
ADRLRAVGDDPEAVRAIGVEVATALAGRLLAEGAPGIHFITLNRSTATREVWRNLRDGIG
G
>A0A6J5CME6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sediminicola|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRGQLASLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFAHKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCGRLIEAKVPGLHFYTLNGAAATKAICERLGA
>A0A1T3CAK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma guizhouense|TrEMBL
MHIKSLVAETEKSKAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLEKVNDALQKAYKAGCTNILALRGDPPRDQES
WTAADGNFQYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGAGF
IVTQMFYDADNFIRWVGKVRERGITIPILPGIMPIATYASFLRRCKHMQCRVPPDWMAKL
EPVKNDDVAVREIGKTLVAEMCKKLLANGIHHLHFYTMNLAQATRMVLDELNWTPSAENP
LKQALPWKQSKGFGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPASIQDIANTFVQYLEKKLETLPWSESGLAAEADPIKDDLVA
LNKRGLLTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLMPPYLLDEMISRLDDFP
NLTYYAVTKNGQLKSNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGVDW
AHCFDANTPSRALIEGIMNEWYLVNIVNNDFRENSTIFGFLEGLEVKDIAVPATPTA
>C7GX60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain JAY291)|TrEMBL
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRD
AENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDVKLDLEYLKQKID
AGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQH
FSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANKCLELWSTPTSINDVAFLVINYLNGNLKCLPWSDIPIN
DEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL
>A0A1G3TCJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp. RIFCSPLOWO2_12_36_12|TrEMBL
MFDELINKLNNGTYITLETTPSHSPVFSPIVETIAELGLDKLVDGFTTTDNPLAKLKYNS
LFAAKMLQDRFKKPVIATMSMRDRNKIALQSDLLGANEADIRAILALTGDPATISDQPHT
KGVFESDSSLLLDIISCFNSGINYAGKPFTHKPKEIYPFAVVNSYAKNPKTLQKKMLKKI
KHGALGIITQPVYDIQNAKLLLELKEAANKECHSENKSAELILGVFPITKLRTAQFLSAH
VPGINVPEEWIEALRVANEKGADEEYRVGFELSKKLFLELKALHPKL
>A0A3S1QRB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.005.03.2.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A512T4A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Knoellia locipacati|TrEMBL
MSFEFFPPKDDASEAALWDAIRRLERVHPDFVSVTYGAGGTTQDRTVRVTERIARETTLT
PLAHLTCVGASVGDIRRVVGQYAAAGVRNILALRGDPPGNPGGEWVAHPEGLDHATDLVD
LIRTLGDFTIGVAAFPDVHPASPDLDHDVEVMVRKADAGASFAITQMVFDADTYLRLRDR
VAQHRDLPITPGLMPVTNLKQITRMAQLMGTPLPRAVVDRLEAVAGDADAVRSVGVQIAT
ELAQRMLSEGAPGLHFITMNRSTATLEVHENLGLSTGAR
>A0A2T4ND06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. A244|TrEMBL
MALGTASIRSDHARTVRDMLAAGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSLDWDTDVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLERIGSLTNAAF
PAALKERILTAEDDPAAVRSIGIEFATEFCAQLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSPQA
>A0A2N7QTW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella sp. AD56|TrEMBL
MSSISFEFFPPKTDEQRDQLDQAAKLLKSHAPEYVSVTFGAGGSTLSYTGETVHRLHTSH
GLSVAPHLSCVGGTRAELAALLDDYRAAGYRRIVALRGDLPSGMATPGDFRYASELVRFI
REHSGDHFHIEVAAYPEVHPQADDALADLRHFKAKVDAGANSAITQYFYNADAYFRFVDD
ARKLGVKVPIVPGIMPISNFSQLKRFSDACGAEIPRWIVKRMQAHGDDAASVRELGADVV
AQLCRRLLEGGAPGLHFYTLNRARATRSILDRLHG
>A0A0T9UPF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia aleksiciae|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDASPTQLREIAADYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A7K4MYK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marine Group I thaumarchaeote|TrEMBL
MTVRYEINPPKISDDGQDVRNVLFERIETISSVCNGIHLTDSVLGIPRVSPFEIAKQIRE
SNKNIKLTCSLRVRDKNLNDIEKIVQESIGTVDGILVLMGDKSDTMSNKDNLIPSQVVKA
LNDNGLDKKIELFLSLPSNPNFAKIQKKIDAKPVGFVTQVIHSKDQVEKIVNYLRPNGFK
IIPCLLLPSKNNLKSAEFLKIDWSNYEENIIEFINEIHSIDSEILVTSPNDFKRAHETLT
KLAT
>A0A8G0LUF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MSLKDTFKNKTVFSLEVYPPKTPEGTKKLVNALTGIKRIKPDFISITLGAGGSQNNNALE
LSSMIQNDLNIPAMAHIPGIYRSKKDVADFLKQLKQHNINNVLALRGDINPDETPVGDFN
HASELAEFIKTQGDFDITGACYPQKHPESVDLVDDTLHLKEKVDNGVGHLITQMVFDNQA
FYDFRQRLKLAGINVPVEVGIMPCTNCNQIKHITELSGLEMPKKFVDIMNKYANNKEAMR
DAGIAYAVDQIVDLVANGVDGIHLYTMNNTYVAKKIWEATHSLFEATSYQLQHPSLSGSD
NQ
>A0A1V5U761|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium ADurb.Bin242|TrEMBL
MEIPAVKHSADKLQERLNRFAERYRRIVEAGHGVCLTDNAMGNLAFQGHELIRELGLPVP
SGRVMVHINTFHTRKELHEIVDSCAEMGVGELLVVSGDGSARLPKLKPSDLEADVPGITS
VELLAYLRRQYKDIFRYGAVFNQYEPPEHEKEKLRRKLEAGAEFIITQPVLPGDPEIGEL
RRTLPVPLFLEVWMSPKIDLLSQCVGRKIGISSYDPLESLENMHRTYPECPAYLAMVDFK
TQFDQLARSGEKTA
>A0A1G8R5R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aneurinibacillus migulanus|TrEMBL
MPQENIKTYLKDNLLIGDGAMATWLYRLGVPIGVCYEELNLSNPEIIGTVHRSYYEAGAR
FIQTNTYGAHRDALARHGLQDQVQRINRSAVQVARRAVGDDAYVVGGIGSINAGRVRNME
QIGTYGDQYEEQASALLSENVDAILLETFLDVDELLLALDVIRPLTDLPIIAQLATIEVG
RTRDGHTLTRAFAELVKAGADIVGLNCRMGPAEVLRSIEGAVVPEDTPLSVFPNAGRLAM
SDGEYSYASVPQYFGDSALRFRAQGARLIGGCCGTTPEHIRMMAQVLAEREPLPRVNPEV
QIEEAQTPIRVVPPVRPKGIVDTVTQRHTVIVELDPPRDLDTEKFLQGTAELRDAGADAI
TLADNSLATTRMSNLALGSIMKTKLSAEPLLHIACRDRNLIGQQSHLMGLHALGINQVLV
ITGDPARFGDLPGASSVFDVSSFDLIRMIKQLNEGYSFSGKPLQQRANFVVGAAFNPHVR
QFDAALRRLEKKVEAGADYIMTQPVYDQETIELIYQGTKHLNIPIFIGIMPLTSSRNAEF
LHNEVPGIKLSDEARERMSRYEPGEEARREGISIARELVDMAMDRFKGIYLITPFFYYQM
TAELTRYIHEQSNLGLSAQK
>A0A7D5NFV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kapabacteria bacterium|TrEMBL
MKDFLSQLGERVLLFDGGMGTELYRRGIFINKCFEETNLSAPELVKQIHIDYINAGAQAI
ETNTFGANRFKLKRFNIQDKLYDIVLAGAKLAREVAGEKVFVAGSIGPLGVQIEPLGPIS
REEAQEYFTEVIKPLLDGGADLLIFETFINIDELRQAVIAARKMTTIPIIAQITIDEYGN
TLTGTDPETTISELESIGADVIGVNCTVGPQTMLDWLERVRPLTSLPISIMPNAGKPKNV
DGRNIYLASPEYFAEYAKLFVRSGANIVGGCCGTNPEHIKKMSTAILALQPKITFQKIEK
ITLKEEPKVKPIEKKDKSRLARRLLQGHFVKFVELLSPRGVDPSKEINKARELFYNGIDV
INIPDGPRASARMSALALAVKIQREVGIETVLHFVCRDRNVIGIQSDLLGAYALGIRNIL
AITGDPPKLGTYPDATGVFDVDSIGLVNILTRLNNGLDIAGYPIGDPTGFFIGVGVNPLA
VNLDEELRRLYWKVDAGAEFIVTQPIFDVAGFKSFLKQIEHYRLPVIAGIWPLTSLRNAE
FMKNEVPGVVVPDEIIDRMRKVADSKERSLEEGIAIARETISEIRHLIQGVQISAPFGRI
DAVMQTLEGIE
>A0A1I0B6T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorsellia anophelis DSM 18579|TrEMBL
MTFFYAQHTEALNQNLAELQGKINVSFEFFPPRTEEMEKTLWHSIERLSTLKPKFVSVTY
GANSGERDRTHSIIKEIKTKTGLIAAPHLTCIDASRDQLIEIAKDYWANGIRHIVALRGD
LPEGSGKPDMYASDLVTLLKSVADFDISVAAYPEVHPEAKSAEADLINLKAKFEAGANRA
ITQFFFDIESFLRFRDRCVSVGIEAEIVPGILPVSNFAQLQKFATMTNVKVPSWMNGMFQ
GLEHDAETRKMVGASIAMEMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPMA
>A0A318YPB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus neoniger (strain CBS 115656)|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A0D6EP83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporidiobolus salmonicolor|TrEMBL
MVKISDKIRKAEREGRPWWSLEFFPPKTPDGWVNLYDRIERMQQLGPIFVDITWGAGGST
SEATTNFVKTAHAQLGLETCMHLTCTNMPVEMVDQALKEAYDSGCRNILALRGDPPRGVE
EWKPTEGGFNHAIDLVRHIRAKYGDYFDIGVAGFPEGHPQSESPEIEIKHLKAKVDAGAN
VIFTQMFYDADVFIDWGRRLRAAGITIPIVPGIMPIQTFASFKRRTNFAGTIVPQELLDV
LEPIQDDDVKVREAGTKYVAQMCRKVLGAGLGIHGIHCYTMNLSRGTEMLLEELNFVPHS
DIVKPLPWRLSLTSKRRTESTRPIFWSNRQRSYLSRTSEWDEFPNGRWGNQASPAFGDLD
SLVLSLPQKPRDAINLWGTPSSLQDVADLFARFCQGQLRSLPWSDQPAAKETGRIAEGLA
KINELGFLTINSQPRVDGAQSEDPAFGWGPINGYVYQKAYLEFFCPPEHVEDLLEILNKT
PSITYHAVDKSGSFRSNTAAGPNAVTWGVFPGAEVIQPTVVDSTAFQSWKDEAYELGQQW
ATLYQSMAPETSAVIRKIFGEFHLVNIVYNDYKDPNEDAVFKPFFELAKLKNITSAADSS
AAVANGH
>A0A434V3D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1E.F.Ca.ET.063.01.1.1|TrEMBL
LKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRAITQFFFDNDLYERYVERA
RRAGIYIPIVPGILPVHSFTQVANFSSRCGALVPAWLAERFEGLENDPQTHALVASAVAA
EQVLDLVERGVSDFHFYTMNRADLVFAVCHMIGIRSHEADVAGSAAA
>A0A0P9PDM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. coryli|TrEMBL
MSQERRFSFEFFPTKTDTGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A133KM80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum|TrEMBL
MFSLEVFPPKRDAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIANTIHGEYG
IPAVAHLTALYSDEAKIDEALDMFEAAGVSAVLALRGDYIDGEEPVGRFNHASDLAAYIH
DRKPDLKVFGACYPEGHYSAASLDEDIGNLKIKVDAGVTHLISQLFYDNDDFYRFLDKAH
AAGIDVPIEAGIMPVRGGKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGIIYASD
QIADLVAHGVDGVHLYSMNHPATTRRIWHNVEPLFTVE
>A0A516N554|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulosimicrobium cellulans|TrEMBL
MTSEASFAHRPGRPRPTVSFELMPPRRPDAAPKFWETARRLVATHPDFVSVTYGAAGTDR
ATARQVVGRLLQGTPVLPIAHLTCVGASREDVESVITDFLDEGVRSFLALRGDPPRDQPD
WQPAPDGVRSSTELVALLREVEASRCASDPAVALRGAARPLTIAVATFCDGNPAAGTTRA
QEVRRLWQKQQAGASFAITQLFYDASSYTDFVAEARAAGVTIPILAGLLPTTEPARLRRV
EELTGVRAPQHLLDALDALPDPEAQHAYGIAYSVDLAQRVLDAGTPGLHVYTFNKHRAAL
DLLEGVHLGGGSVGTGGGASAAAAPLVPDLASGPWVTGTSLPTTSAATHGAPV
>A0A7V9HAI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIDEAIAQSDQPTFSFEFFPPKTPEGETNLEAALAELQHMDPTFVSVTYGAGGTTEEKH
RTVETVARIKEHHGLEVMAHFTCVGATVDELRRMLDRMAEAGIRNVLALRGDPPPGQDWT
ATEGGLSYSRELVELIRDEYDFAIGAAAFPETHIHAESPEADLAYLKAKVDAGVGFLVTQ
LFFDNNDYVDFVARARAAGIEVPIIPGIWPVTNYKQIARVTSLVGSRLPEPLLSELDARI
DQPEAVAGFGVAYATLQCADLLARGAPGIHFYTLNKSPATRAIMSALRAMAPWRGAVPV
>S5CDY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas mediterranea UM7|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASREELKQIAKDYWDSGIRRIVALRGDLP
PGLEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDIDLVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGA
>A0A834AIA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllostomus discolor|TrEMBL
MDLPNPEVLPAGHCWPSLGMRALEAGIVSLSVPPSISKDSAMVNEPRGNSGPGAHWEGSS
CGIENSKDSLKGSSPGLDPERRERLREKMKRKMESGDKWFSLEFFPPRMAQGAVNLIAMF
DQMGAGGPLFIDVTWRPTQDPGSDKETSSMTIASTAVNYCGLETMLHMTCLCQSREAVTG
HLRKARRLGLKNILALRGDPPGEQWEEEEGEFSHATDLVKHIRSEFGDYFDICVAGYPKG
HPDAVSFEDDLKHLKEKVTAGADFIITQLFFEADTFFLFVDACSKIGITCPILPGIFLIQ
SYHSLRQLMKLSKLEVPQSIRDVIEPIKDNDDAICNYGIDQAVSLCRKLLASGLVPGLHF
YTLNRLKATTEVLKRLGMWTEEPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTRD
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKAPREELLKMWGEQLSSEKSVFDVFVRYLS
GEPNQNGHPVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPRVNGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVEALLRVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWVERWGKLYDEKSPSRRIIQHIHDNYFLVN
LVDNEFPLDSCLWQVLEDTLELLNRPMSE
>A0A7W1QDJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MARPPAEPDNMKLRDIYAQPGKTFSVEFFPPKDEAGVERLFRQVDEIKKLSPAFCSVTYG
AGGSTQGRTLEIVRRLRREAELEVMSHLTVVNQPRSQVHSVLEFLRDNDVENVIALAGDP
PAGTDGGWAAHPDGYHHSRELVEEALRIDPGWFSVAVAGFPEIHPRAESHESDLRYLKEK
VDAGADVIVTQLFFDNDDYYRYVEDVRAIGIEVPIVPGMLPIQTARQCRRFTTLCGAKIP
PRLDALLTRVEDDDDDAVQLGIDYTTEQCQDLLEFGVPGFHFYSLNRARSVTAIFENLKL
QTLAATT
>A0A7X0DBA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhizobium flavum|TrEMBL
MTPTLPPQKSFGLSFEFFPPRSADMEGQLWDAVLDLGAWNPDFVSVTYGAGGSTKAPTLS
VVRRLIRETALPTAAHLTCVDASREETRSVVEEFRAAGVRRIVALRGDPASGVGTEYRPH
ADGYANAAELVAGLREIGNFDISVSAYPEKHPESADLAFDIEMLKRKADAGAARALTQFF
FDNDVYERYLDKVRAAGIDMPIVPGIMPIQNLTQLKRFAGRCGASVPTFLDRRFEGYEEN
PADRAKVAADVAAEQIDDLLNRGVTDFHIYTMNRSGLINQVLEQLGRARRAQADAAA
>A0A1Q3T6H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium 44-61|TrEMBL
MKVIDHIKQAKETLISFEVLPPLKGKGIEALYKHLDPLMEFKPSFINVTYHRSEHIFKKR
ADGSFEKVVIRKRPGTESICAAIMNKYNVDTVPHLICGGFNINETEDALINLRYLGIDNV
LVLRGDAAKNETTFDAEPGGHRYASELLKQVTNLNAGIYLEEDLKSTQKTEFCIGVAGYP
EKHFEAPNMQTDLRYLKEKVDCGADYIVTQMFFDNEKFYAFVKSCREAGITVPIIPGLKP
IYNKKQLTVLPKTFHIDLPAELANEVLKCKTDLEVEEIGKEWLLAQSKDLKKNGVPVLHY
YTLGKPHMVADVVRQLL
>A0A1M6GX13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenxinia saemankumensis|TrEMBL
MTRPAALSFEFFPPKSLEASFRLWDCATTLAPLDPEFVSVTYGAGGTTRKLTHEAVAAIH
KTMGLRVAAHLTCVDATRAETMEIVDGYAEAGVSEIVALRGDPPKGSGGFAAHPEGFAGS
VELIEAIAARGGFNIRVGAYPERHPDAATEAADIEHLKRKIDAGATSAITQFFFQAETFF
RFRDACAKAGIDAPIIPGILPVENWAGCQKFAAATGTSIPPLLREGFDRAAADGSAELYA
TAVATQLCDNLLEGGVEHLHFYTLNRPELTRDVCHALGLAPPVALEQVA
>A0A1M6LW61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubritalea squalenifaciens DSM 18772|TrEMBL
MHIQDIIKQDGPSLSFEFFPPRTKEASDALYETIAELEPYKPSFVSVTYGAGGTTRDLTH
DLVLRIKETTAIPPVPHLTCIGHTKAEIESILIRYAEAGVSNILALRGDPPRDNPNYDRS
GDDFKFAADLVAFIKKFNESGRHPDPRGFGIGVAGFPEGHPATPNRMLEMEYLKAKVDAG
ADYICTQLFFDNHDFLDYRERCEIEGIHIPILAGIMPVTSTKGMKRMAELAEGARYPAKL
LRALQRAGDNPESVERVGIHYAAQQCAELLDADVAGIHFYTLNKSKATREIYASLGLSQL
QS
>A0A323U2Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meiothermus sp. Pnk-1|TrEMBL
MKIHTQFAPGKPLFSFEFFPPKTEEGEAQLFRTLHVLKPLQPAFVSVTYGAGGSARGKTV
EWVGRIKKEVGLEVMAHLTCVGATREEIGEVLEQLRQVGAENLMAIRGDPPRGQQEFRPV
EGGFRYANELIAFIRERYGDAFCIAGGAYPEGHPEAPSLEADLRNLKRKVDAGLDFLVTQ
LFFNNALYLGFVERARKVGIEVPIVPGLMPITNLAQVRRFTEMCGASLPGPLLAQLERFA
DDPQAVLEIGVEHATRQALELLEAGAPGIHFYTLNKSPATRWVVENLRSRMARSA
>A0A2H1IEP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium antiquum CNRZ 918|TrEMBL
MSQANLSTLLKSARYEILPTAGVVDRVHEYVAPGRVITVTASTGLTLEATLSTAEQLQAL
GFQAVPHIAARMVQSRTELEEIVARIAQAGIDRIFVPAGDATPPAGGYAGALDLIVDLAS
MAAPIQHLGVSAYPETHPLISDDVTVQAMWDKRDYATHLVSNLCFDPGVIATWLARVRAR
GIELPLVLGIAGKVELTKLARVAGKIGVGESTRFLRKNTATFSRMAKPGGYNPRKFLDKL
APTLDNPAMGVVGLHIYTFNQIKDTEIWRRKQLAALGHTDEATISNG
>U7VAU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cetobacterium somerae ATCC BAA-474|TrEMBL
MDFMKIKNLYKIKKPVISFEIFPPNEKYPIESVYETIDELAKLKPDFISVTYGAGGTIRG
RTVEIASRIKKVYGIEPLSHLTCFGAKNNEIEDILKKLKKNNVENILALRGDFPKDNSEI
KGDFKYASKLIEKIKKEKEFCVGAAFYPEGHQETNDLLDLFYLKEKVKEGADFLISQIFF
DNNYFYDFKNKCDKLGINIPLIPGIIPVTNAKQINKITELCGSTIPPKFQKILTRYENNP
EALKEAGIAYAVEQIIDLLSSGVPGIHIYTMNKVDVVTEIMRRIKYVKEHLQEVN
>A0A0S1Y572|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella sp. N|TrEMBL
MTDTKTPALSLEFFPPRDIAAQERLVRAAKQMLAMHPRYVSVTFGAGGSTREGTADTVRT
MRNLGVPAAPHLSCVGASRDDLRGILNAYREEGVKQVVALRGDLPSGMGGDAGELRYARD
LVAFIREETGDWFHIEVAAYPESHPQAENSTADLDHFVEKVQAGANSAITQYFFNADAYF
DFVDRASAKGVTVPIVPGIMPITNHSQLLRFSQMCGAEVPRWIRMRLAEFGDDKASIRAF
GIDVVSDLCRRLLDQGAPGLHFYTLNNAEAPMAIWQNLGV
>A0A1F4JZA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFCSPLOWO2_02_FULL_57_36|TrEMBL
MSDKIFSIEFFPPKTPEGVEKLRVARAKLAELHPSYFSVTFGAGGSTQQGTRDTVLEIKR
EGHEAAPHLSCMGTSRDNLRSLLQDYKSHGIKRLVALRGDLPSGYGTIGFSSGEFRYASE
LVEFVRAETGDWFHIEVAAYPEVHPQAKSPQDDLQNFARKVKAGANTAITQYFYNPDAYF
RFVEDAQKIGVNVPIIAGIMPITNYSQLMRFSDMCGAEIPRWIRLKLASFGDDSESIRAF
GLDVVTRLCERLLAGDVPGLHFYSLNQANATLAICHNLGTPSV
>A0A5E9I1D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CH235|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNDYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A2S6B2S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas sp. KAs_5_3|TrEMBL
MPIPVSFEFYPPKTDEQRAQLDRTADKLKAHSPEYVSCTFGAGGSTLSYTSETVRHLNQH
HGFDAAPHLSCVGGSREEIRELLRLYRALGCKRIVALRGDLPSGMGHPGDLRYASELIEF
IRAEHGDTFHIEVGAYPETHPQAEDTLTDLRHFKAKVDAGADGAITQYFYNPDAYFHFVD
AVRKLGVEIPIIPGIMPISNFAQLRRFSEACGAEIPRWIGKRMQALGDDADAIRDFGADV
VANLCERLLAGGAPSLHFYTLNLAKPTQTVLSRLG
>A0A6M8SRH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deefgea sp. D17|TrEMBL
MTNPLRPISFEFFPPKTDEGAAKLATTRRQLAQFNPEFFSVTFGAGGTTQEGTLRAVVDI
QAAGHAAAPHLSCIGSTKDNIRQVVQQYKNHGIKHIVALRGDIPSGMGEFGEFRYANELV
SFLRSEFGDWFHIEVAAYPEFHPQSPSAEADLRHFINKVNAGADSAITQYFFNADAYFRF
VDEVQARGVSIPIVPGIMPIQNYSQLQRFSDMCGAEIPRWLRLRLQAYSDDTASIRAFGL
DFVTELSDRLLAGGAPGLHFYTLNAAGAVSTVCQRLGY
>A0A1G0LHM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium GWB2_52_12|TrEMBL
MNNKTVIDRFRSEILAGDGAVGTMLYTKGISLDSNFEHLNLIRPSLVLELAREYVAAGAQ
VIETNTFGANYTKLAAIGLGHRVAEINTAGARIARQAADQDNSILVAGSVGPLVRIKGEE
HELGSSEMQEIFSVQCAALAAGGVDLILLETFASLPQLSAAVAAARATGLPVCACMAFLE
GGRSSDGTTVELFCDTMEQAGADMLGANCGAGPLELVKVVRRLASRTDKPIAAYANSGFP
EYRDGRYIYRATPDYLASMAEEMASSGATLIGGCCGTTPEHIAAIARRLAGTLPALRTRP
PEVAVSQTTDNRNNENVSFLTPWGQRKIITVELDPPKGMDCSRIIASCRRLKEAGADAIN
LAENPLARPRMGNIALGSLIQREVGIEVIVHITGRDRNLIGMQSDLMGASLLGIRSILAV
TGDPATMGDHAGAKSVFDLHSFTLIKLLSDLNRGVNAIGNPIGSGTGFTIGAAFNPNTSN
MALQAERLLKKVSNGAEFVQTQPIYDPAVLFNALKAIRDINVPFLAGVMPLVSERNAEYL
HNEVPGISVPTAVRTRMKGLDKEAGVQEGLAISREFIHATFATVGGYYLMPPFGKHELAL
ELIDYIHDLEKEHIR
>A0A0B5H0U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula sp. CBA1115|TrEMBL
MALGTRAVSDSQGVRTLLTSARFELMPFESFDEEITHLPDDATIAITTSPQLGIEKTVEK
TEEAAEMGFDVVPHIAARYVEDREQLEAIAERLEQAGITDIFVPGGDREEPAGEYESALD
MLEVLAETEYSFDEIGITGYPEGHDFINDETLAESMAQKAPYATYIVTQLCYDPDAVLEW
VEDIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDDEYNIRGVHIYTFNQTPDTEKWRHNRLDS
>F8AYD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Frankia datiscae|TrEMBL
MATRGLVATRGLTVRDCLDSGRPSFSFEFFPPRTPEGERHLWTAIRELEPLRPSFVSVTY
GAGGSTRAGTVRITERIATETTLTPIGHLTAVNHSVAELRQVIGSYAGAGVRNVLALRGD
PPGDPQGEWVAHPQGLHHAEELVRLVQSLGDFCVGVAAFPDRHPRSSDFDTDARYLVRKL
TAGADYAITQFFFEADAYFRLVDRVRQLGCEAPIIPGVMPVTNVAQIERMAKLSGAAFPP
DLARRLHAVADDPAAVRAVGVEVAADLCEKLLAGGAPGIHFITLNRSTATREVFHSLRR
>A0A1H1SFR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. HL-111|TrEMBL
MPPTLDELHEHRTALDTPLFSGLPGDVDVSFEFFPPKTEKMEAQLWDAVQQLKVLAPEFV
SVTYGAGGSTRERTHATVSRIIREAGLPAAAHLTCVGASKAEIREVAEQYWEAGVRRIVA
LRGDAGEPGAPFTPHPDGYAGAAELVAGLKEIADFDISVAAYPETHPDADCPQACIDHLK
RKLDAGASRAITQFFFSPETFFRYRDALAASGIDKPVIPGILPVTNVAQARKFAGACGAT
IPGWMDGLFEGLDEKPAARQLVAATVAAELCRRLYAGGVRNFHFYTLNRPDLAYAICHML
GKRPVGEAAAAPAAAVQGEAA
>A0A317VL46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus heteromorphus CBS 117.55|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLSKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVHYIRSKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDSDNFIEWVKKCRDKGVNVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLVASGINHLHFYTMNLAQSTQLVLDELKLMPSEETP
IQRALPWRPSLGLNRREEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHTFVDFLEGKLARLPWSDTPITTEANAIKDSLIE
LNKKAIFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLLDELFARIEKNG
DLTYHAISKNGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDSWSLVNIVNNDFHNTSSLFDLFKDLDVKDLDTEIPAENSESK
AHLNGASNGATNGVTNGTTSESAVKN
>A0A5R1WYE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. 3R11|TrEMBL
MTQHNFSIEFFPPKTPEGTEKLRVTRAKLAELQPKYFSVTFGAGGSTQQGTLDTVLEIIR
EGHVAAPHLSCIGSSRDALRAILTEYKSHGIKKLVALRGDLPSGFGAADFSSGEFRYANE
LVEFIRAETGDWFHIEVGAYPEMHPQAKSPQDDVQNFARKIKAGADAAITQYFYNPDAYF
NFVDEAQKLGVNAPIVPGIMPITNYTQLMRFSDMCGTEIPRWIRLKLASYGDDADSIRAF
GLDVVTQLCEQLLEGGAPGLHFYTLNQPAATMAIWQRLVD
>A0A069QJS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella loescheii DSM 19665 = JCM 12249 = ATCC 15930|TrEMBL
MKMKVSDFLNKKAAAKALSFEVLPPLKGNGTAQLFRTIDRLREFDPNYINITTHNSEFVY
RQLDNGQYERDRIRRRPGTIAIAAAIQQRYGIPVIPHIICSGATVESTEYELLDLQFLGI
QNLLLLRGDKAHDERMFTPTPNGHAHTTDLIEQVNRFNEGFFADGTPMKHPGESFEYGVA
CYPEKHEEAPNLDMDIDYLFLKQQLGAKYAVTQLFYDNQKFFDFVAKARQRGVTIPIVPG
IKPFAKLGQLSVIPRTFHCDLPTALAHEIVKCKTDDDAKALGVEWATQQCRELYAHGVPS
IHFYTVSAVDSICEVAKKLL
>K2K2F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallaecimonas xiamenensis 3-C-1|TrEMBL
MSLSHAQHLELLNHSVSELKDDIQVSFEFFPPGTEKAEASLWEALDRLVPLAPRFVSVTY
GHSEEGRERTHKVIKQIGERTGLTAAPHLTCIDTPEAELRQIARDYWQNGIRHIVALRGD
KQPGRQYTNYYASDLVRILREEGDFDISVAAYPEVHPEAKSAQADLLALRKKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIVPGILPVSNFETLKRFADLTNVAVPSWLAQRFA
GLENDPTTRSLVGASIAIDQVRVLRKEGVKEFHFYTLNRAEQSYAICHTLGVRPQLAKAC
>A0A087GZA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabis alpina|TrEMBL
MKVVDKIKSVTEQGKTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGSTA
DLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIKSKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKENDEAVKAYGIHYATEMCKKILAHGITTLHLYTLNVDKSAIGILMNL
GLIDESKISRSLPWRRPANLFRIKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYCTLSDYQFTRPKARDKKLQQDWVVPLKSIEDVQEKFKELCLGSLKSSPWSELDGLQPE
TKIIGEQLGKINSNGFLTINSQPSVNAAKSETPAIGWGGPGGYVYQKAYLEFFCSKDKLD
TIVEKSKAFASITYMAVNKAENWVSNIGESDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNDYINGDIFSVFA
>E8T1Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermovibrio ammonificans (strain DSM 15698 / JCM 12110 / HB-1)|TrEMBL
MSFRQKLEAGKFVITAEVAPPRGTVFSLEALEPLKGKVDAFNVTDCQRSMVRMSPLVAAK
LLLDAGFEPVLQLTCRDRNRIALQADLLGAWALGLENLCLMTGDFTTLGDQPDAKPVFDL
DSVQLIELASSLNGGKLLNGKEIDHPTDFFIGAVFNPFAGPERLQLFKLEKKVKAGARFI
QTQPVYSLEVAQRACSQIREAGAVPIVGLLPVKSLKMASFIEKLNPGSVPPSLLEGLERS
RDPARYGWEFILELAEAVTEFAGGVHFMLTGRPDQLARFIDYLRNSSPYNHRF
>A0A1F3LPT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWF2_42_66|TrEMBL
MKVIDIIKNSEKPIFSFELLPPLKGNDASKIYNTVESLVDFDPKYINITTHRDEMIYKEL
PNGAIEKRVVRKRPGTVAIAAAIQHKYNIPVIPHILCGGFSKSETEHVLIDLNFMGIDNV
LALRGDGQKTDHVFKPNPDGHSNANELVEQIVNLRSGKYLEEDLRNSAPLDFCIGVAGYP
EKHFEAPNFETDLENLKRKVDAGADYIVTQMFFDNQKYYDFVARCRAIGITVPIIPGIKP
INLKNQLTVLPKIFNIDIPVELANELAKCKDDAAAKQVGTEWAIQQSKDLIANKISSLHI
YTYGVSDNTRKIVEAVF
>D2ZM41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cancerogenus ATCC 35316|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLRRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2V1HPI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. S1B|TrEMBL
MSALSHYLQQQQFCLVLEQIVSKRTELLPISTLAGLPCVMAFADRVHADDDPSPITLAQS
VSTDQAKLLHFSGKARDVKDLQQFIEQAKQNHMHDLLLLTGDKLKQHNFGKQNPRQRTRY
LESVSALMCVKTHAPDMYCGVAFNPFKYTESEEQAQYLKFEKKQRAGADFVITQLGYDLN
KILKFKQFVDASTQPCPVLACVMPLTYRRAKFMVKQQVAGIEISPHLLQHLKVEQQQNAA
WAEQRVYARAALQIWIYRHWGLAGIHVSGCQNPEQQALLEQALAQYQTWTLEQCLMEWNH
LCKIVRGDEMQPDLSAAYPQQQPSVLKYQVLQVTHDWLFDSTLAQKIGRFVFQLGFWQHG
LAAKGILAVEYVSKHAAVGCESCGQCRLAETLYICPETCPKGLANGPCGGTKLDRCEFAD
RECIHSQKYRLAKQVRQQDILRRELIPAVPVELRQTSSWVNWFNPKSH
>A0A7L9MHG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella suis bv. 4|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATCEDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMVGIRPKTQAAL
EVA
>A0A846GYV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO1G6|TrEMBL
MTNPTKNSFRTAVESGEFLITGEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQEGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQGTDLFTGAAVDPQLKSWSGLQRRFER
KLEAGAQFFQSQLICDFDRLEKFMNQIAAGSNKPILAGIFLLKSAKNAKFINKNVPGVDI
PEEIIDRLAAADNQLQEGIKIAAEQVKLARQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSPVNDLVFK
>A0A6M1Q3U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parapusillimonas sp. SGNA-6|TrEMBL
MKITDHIKNAKGKTLFSFELLPPAKGQGIQSIFNTMDELMEFNPPFIDVTYHREDYLYKQ
HTNGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDSDFIPTPGGHAYATDLLQQVVDMNNGKYLHEDIVNSEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKIDMGAEFIVTQMFYNV
>R4K3R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium pasteurianum BC1|TrEMBL
MLKDKILNRETGIITYAITPPKKDNTKEKIAEISQRHLERIKNIDIDGLIIYDIQDETDR
LKDERPFPFLETIDPAAYGKEYLKELKVEKIIYRCVGKYNSQELKQSITSETQRDKFSVF
VGAASRNQEVKLNLSEAYKLKDKFNENFMLGGIVIPERHTKSNDEHMRIVSKAKCGCEFF
VSQVIYNIEASKNLLSDYFYYCQDNNIKMVPILFTLTPCGSTKTLEFMKWLGINIPKWLE
NDLIHSKDILDKSIDLSKSIFEELLDFALDKGIPIGCNIESLSIRKVEIEASIQLVKDIK
AIIENKMRKGDFYK
>A0A7X8RQA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibacter sp. B1|TrEMBL
MKVTEHIKQAKGNTLFSFEIVPPQKGQNIQELYNNIDPLMEFNPPFIDVTTSREEYVYID
KDGLFDRKITRMRPGTVGICASLKYKYNVDAIPHVLCGGFTKEETEYVLVDCHYLGLDNV
MALRGDAMKHEKYFTPTKDGNNYAVELVKQIKNLNKGKYLHEIIETPYNANFCIGVAGYP
EKHMESPSLDTDLRYLKEKVDAGSDYVVTQMFFDNKKYFDFVEKARAIGITVPIIPGIKP
IAVKRHLQILPQVFKLDLPEELILEIEKCKNNSQVRAVGVEWAIKQSKELITRGVPVVHF
YSMGKSDNIKAIAKEIF
>A0A1C4MTJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TverLS-915|TrEMBL
MASGTASTWTSEHPTVAEVLASGKRSYSFEFWAPKTPKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRTGTVRATQAIAENTTLVPVAHLTAVEHSVAELRHMIGQYADGGVRNILAVR
GDPPGDPLGDWVAREDGLTYAAELVRLIKESGNFCVGVAAFPDMHPRSENWDSDVRYFVD
KCRAGADYAITQMFFDPASYLRLRDRLSAAGCETPVIPEVMPVTSVRQLERLSRLSTAVF
PETVKERMLAAKDDPAAVRSLGIEFATEFCARLLAEDVPGLHFITLNNSTATLEIHENLG
LPHHRP
>A0A1W9TXP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_19|TrEMBL
MQLKTKIEKGKFVLLAEMEPPKGADATMMLENAEKIRGAIDAFVVPEMSNAVMRMSSLGG
SVLLQQRGLDVVMQINCRDRNRLALQADILAAYACGITSIMAVEGVAPSFGDHHETRAVY
DIRLNTLLTTIQTLQKGHDMAGVDLIGAPKFAIGTTINPGTAGIMLDKELAKMEEQIDSG
VQFFITPPLFDINAIEPFLKRIDNKRSFIIPTILLLKSVGMARYMDRNVEHVHIPAELIK
RIQKAPDKARECISVSKEMVEMLKKESFCGAMISTIGWENKLPEILGVM
>A0A502BUG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella gallinifaecis|TrEMBL
MGFYGLSRRSDIGQTTRVSFEFFPPKSEEMEQRLWETVTRLAPLKPEFVSVTYGAGGSTR
ERTIRTVARILKETDVAPAAHLTCVDATCEEVDRVAQEFAALGVNRFVTLRGDPAAGIGE
KYVPTPGGYQNGAELVGGLRKLADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVHNFCARSGTHIPAWLAERFD
GLENDPHTHQLVAAAIAAEQVMDLIERGIQDFHFYTMNRADLPYAICHMIGIRPQTEVA
>A0A3D1YIU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halieaceae bacterium|TrEMBL
MSVPSVSFEFFPPKTEEGNRTLFETASRLSSLSPEFVSVTYGAGGSTREPTAKAVSELKE
KLGFDVAPHLTCVDASKEETLEIVRDYLNQGITKLVTLRGDPRDGVEGVYTPPADGFAYA
SDLVAGLRDLERLELFVSAYPEVHPGTPSATFDIEVLKRKQDNGASAAITQFFFNNDDFF
RYRDRAATAGVTMPIIPGIMVPENIKGVLRFAKACGATVPSSLSSRFAGIEDDEETRRLI
ATHFTIQQCEQLVTAGVKHFHLYTLNRAESAYAVCHALGLREQLVEAA
>A0A2N3B195|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HGW-Alphaproteobacteria-7|TrEMBL
MTPTLDQLHEYRTATDAPLFSGLPGDVAVSFEFFPPKSEKMEAQLWDAVTQLKPLAPSFV
SVTYGAGGSTRERTHATVARIIAEAGLPAAAHLTCVAASKADIREVAEQYWDAGVRHIVA
LRGDAGEPGAPFTPHPEGYASAAELVAGLKDIADFEISVAAYPETHPDAVSSAADIDNLK
RKLDAGASRAISQFFFSAETFFRFRDQCAAAGIAAPILPGILPVTNVAQARKFAGACGAA
IPAWMDGLFEGLDVKPAARQLVAATVAAELCRRLYAGGVRDFHFYTLNRPELAYAICHLL
GKRPVGEAA
>A0A1C0YP50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caryophanon latum|TrEMBL
MKLLERLQNEVLTADGAIGTVLYSYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
SYGANAIKLARYGLENDVVKLNTAAIALAKKAAADGGQYVLATIGGIRGIRKSDVTLDDI
LAVVKEQAEALIAGQPDGILLETYYDFEELTETVKLVRSLTQLPIVAQVSMHEPGVLQNG
LSLNDAFAELEALGANIVGVNCRLGPHHTIQAFETVELPKNAFMSAYPNASLLDIEEGRV
VYESEIDYYAKAAVELRNQGVRLIGGCCGTTPKHIQAVKAALTELSPVTAKDAKEQPVVK
MRDAEPREQQPLHEKAKTERSIIVELDTPRHLEIEGFMEGSRQLYAAGADVVMMADNSLA
SPRISNIAMGALLKEEGIRPLTHLTCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKVG
DFPGAASVYDVSSMELISLIKQLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVARL
EKKIEHGADYFISQPVYTKEKIVEIYEATKHLETPIYIGIMPVTSHKSAQFLHHEVPGIK
LSEDALARMEACGDDKERATAEGIAIAKELVEVAAQYFNGIYLITPFLRYDMTLELMKYI
HQLDEQKKGVQA
>A0A8J2LAJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allacma fusca|TrEMBL
MVGESPSSAGLVLTKHCSEPNAPSVCSSNGRTSDFESDSEDHFPGASHDRGVYGRGRRGS
YQYLSLTEKLQARIESGEPFFSLEFFPPRTKSGAANLLSRLERLRHGGPLFCDITWHPAG
NPGGNSETSSMTIASAALNYCCLETILHMTCTEATVDDLNRHLARAKELGIKNILALRGD
RNEEGRPSDFSYATQLVRHIREEYGNYFVVAVAGYPTGHPEAVSYEEDLKHLKEKVDAGA
DFIITQLFFKPEYFIKFVNDCREIGIRVPIIPGVMPIQSYESLRHMVKLSRLEVPDEIVN
VIKSLKDNDEAIRNFGIHQAVTMIRTLFQSGVAPGVHFYTLNREVAVTCIAKQLGLWNLH
PHRALPWKVVPNHRRCQEEIRPIFWAARPNAYIYRTRHWDEFPNGRWGTAESPAFGDLKD
YYLFYLKSKGSKEELLNMWGFYLESEQDVWDVFYAYITGRENRNGVKVTRIPWNDDELSE
ETIPISEKLATLNRRGVLTINSQPNVNGMPSNDETFGWGQQGGYVYQKAYLEFFTCGKTV
DILKRLLVQYPQVNYHIINKNGKFNYTNAYTNCPIAVTWGVFPGREIIQPTVVDSESYLV
WKDEAFALWIEQWAKLYEDGSKSQQVIENIANTYYLVNLVDNDFPKDTCLWELLNLVLDE
VERESCNNSSKLDQVSSESFDSAISQELSCCENESSDQSHSASPSAAILYIQSVDSMVRR
PTSHY
>A0A7Y2TP37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MHNISFEFFPPRTEEQKLILESTWQKLAPLRPDYLSVTFGAGGSTLDATRDTVEALAAAT
GVPVAPHISCMATSEAMLHDLLQRYSEQGIRRLVVLRGDRPDGTAGPGPFQYANELVGYI
RGEFGDRFLIEVACYPEFHPESPSAESDLHYFRKKVEAGADGAVTQYFYNADSYFAYLDD
CQRAGIDVPITPGVMPITNYRQLARFSAMCGAEIP
>A0A6M1MKU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter sp. SGA-6-6|TrEMBL
MTRTPRISFEFFPPQTLDASFRLWETVQALAPMQPEFVSVTYGAGGTTRKLTHDAVETIH
RHYGLNVAAHLTCVDATKLETLEIASAYLAAGVTEIVALRGDAPKGAARWEPHPQGFASS
VELVDTLARTGRFNIRVGAYPERHPDAAANIDWLKRKIDAGASSAITQFFFEADTFFRFR
DACAAAGISAPIIPGILPIVSWDGARKFALRCGTTVPKKLDEAFTRAIADGREELYALAH
ATQLCDRLIEGGVEDLHFYTLNRPQMTREVVRALGIQPPVALEKVA
>A0A3M1Q7L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MLLIPGSAGAADAPLPPLVERLRQGVLLFDGGIGTEIYGRGVFLNVCYEELNLSRPELVE
EVHRAFLLAGADAIETNTFGASAPRLEAHGLADRLREINAAAVRIARRAANGTAYVAGAV
GPLGIRLEPWGPTSVDEAVALFRQQVEALAEAGVDLVSLETFSDLVEIQAAIRACREVDP
SLPVLAMMTVDEEGRTPEGVPPEWLGRKLDETDAEVIGVNCSVGPASMLPVVEAMAAVTE
RPLAAMPNAGIPRTVDGRMHYLTSPVYMARYVRRFVQAGARVVGGCCGVTPEHIRAMRAV
LAGSAGEQRARPRIVVAAPRGTPHPPVPAEQRSRLARKVAEGRFVTIVEAPPPRGYDAGR
VLENVSRLAAAGVDAVLVPDDPRVTLRMSPLSLALLIVRQTAGGSGRAGTLEPVLQYSCR
DRSLLGMQSDLLGAHALGLRNVMPITGNAPRPGQPVWSPATFDVDAIGLTNVIARLNRGL
DVGDTPIGGQTRFFTAANATVGAPNLDEEIDRLWWKVDAGAEIAVSTPVFSREALARFLE
RIAAFRVPFVAGIWPVSDLREAEHLAGEVPGIDVPHAVLDRLARFDDPADQAREGLAIAR
EVLEAVRPLVEGVYVAGHHDAARALELLDGVVGRAVDERRTFPGRPGIRSGGPDAG
>A0A7Y2YYM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MATPRISFEFFPPRTAEQNLILESTWQKLAPLKPDYLSVTFGAGGSTLEATRDAVEALAA
QTDVPVAPHISCMAQSEDMLRRILEGYRDRGINRLVVLRGDRPEGLAGPGPFQYANELVG
YIRREFGNQFHIEVACYPEFHPESESPQSELFYFKQKVEAGADGAVTQYFYNADSYFRFR
DECCRIGVDIPITPGIMPITNYRQLARFSDMCGAEIPQWIRRRLEGYGDDGASIRAFGLD
VVTQLCERLLAGGAPGLHVYTLNRANASFLLWQRLTTPAQ
>A0A3N5Y6B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MLSPFIDELARRVLVCDGAMGTMLYSKGVFVNRCFESLNLSQPDLVAEIHLGYVRAGADV
VETNTFGANRIKLGSFGLSEKVRAINVAGARVARHAAREQAWVAGAIGPLGIRIEPWGKT
GVDEAEEYFREQAQALLDGPVDLFILETFRDLREIGAAIAAVRGLCDLPIVAQMTIEDDG
HTLDGTPPEKFGPELVRLGAHIVGVNCSVGPAPMLETIERLAETTEAPLAAQPNAGKPRN
IEGRTLYLSSPEYLASYARRFIAKGVRLVGGCCGTTPEHIRQIKLAVGASTAAPARHVAG
PPGAAAVEERGVAPAAREQKSRLAHAMARGKFVHLVELTPPRGHEAAATVEEARRLKIRG
VDAVNVPDGPLSAARMSAISIAVLIEQQAGIETLLHYACRDRTLLGMQSDLLGAHAMGVR
NLLLVTGDPQRQADYAFTGSVLDVDSIGLTNVVSRLNRGVDVGGEALSRQTCYHVGVAVN
PTALNLDEELRRFAYKVEAGAEFAITAPVFDLRAFEVFLARVEGFGIPVVAGLWPFDSQL
NAEFMANEVPGVSVPEALLERMRRAGDAAGAACEGVAIAREIANDLRGRVQGFQLGNAAG
RVDGVLEVFES
>A0A2V8SBC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPLTRTPFLESLKDGALVFDGAMGTQLYERGYFITRSFDEANLSRPDLVLAIHRDYVAAG
AQIIESNTFGANRELLRRYGADDRLRDINRAGVRLARQAAGEEAYVAGSVGPTGRMAGNL
TDERRAALESVFKEQIAALLEEGVDLLVLETFISAGEMEAALKAARALYEGPIVAQMSFS
EERPSIDGLSPALVSEFLGDRGADVIGVNCAEGPAFVYEVAREMLGRGMPVSAQPNAGRP
RRLDERTIYMTTPEYFGVYARRLFQAGVALVGGCCGTGPEHVRRVVDAAAMVRGGRVQVE
AAAAATARPEVGRLASIPPGKKSPLGEKLARVYRERIDPSGPRRGVSGPGSFVVSVEVNP
EPGLDLDKPLAAAAMLRRAGVDVINIADGPRAAARMSNLALGLKAREQAGVDVILHVCCR
DRNLLGLHSDLLGAWVLGIRNLVVITGDPPKMGDYPAATAVFDLDSIGLLRLVDALNHGI
DPAGKPTRDRTGFLCACGAEPAAHDYDRELRRLEEKKRAGAEFIMTQPVYDPALLRRFLD
DTRPLGLPILAGLCPLASARNAEFLHNEVPGMQVPERIRSRMAAASSPEAGRREGVLIAR
DMLEEVKDDVAGVYLMPQFGRARTAVEVLQAVGYRFAPEDDADPQP
>A0A7W0L506|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MLSEDSRSRLRRRFAEQIVVCDGAMGTMLHSTGVPLDRSLCELNVTKPRLVRDLHAAYVS
AGADIIQTNTFDANRLRLSRVGLEDSVVELNIAGARLARDAARDTDRPVLVAGSVGPANS
ATAVSRIPRQMRAEVLREQMAGLIDWVDLLMLETFGDLDSLVQAVEVALQESDLPIVAQM
TFGDDGRTLRGEDPAAVVAALDRLDLAAIGANCTVGPAALQDVIAELAASAELPIVVQPN
AGTPQRLGRQVRYVHNTAYFAAAAAEFVGNGATIVGGCCGTTPAHTRAVAKAVAGLLPSP
RSRRATPTLRERVPVVPSAPEHVPDPPAWPRDAGFVIIAGLAAPQGPDVRGFVDQARELK
AAGAGVLAITEPAPPATRVGPVAAAVVLHERVEAEVLLPAETADRTLPALQADLLGAHAL
GLRMVVCRTGSPRVAGDYPDAAQPWDVDSVRLIAALRGLNEGQDWRGVATRERTRFVIGA
SISTAAADVNREADRAEAKADAGAHFLVTDAIHDADEASLLLAVLPGRGIDIPVIASIAP
FESFRALERLRNEVPEMSAPATGVGGPPRAGGRPVDAVEASVELLEKLRGLISGVLVHVP
RGSQRPAVELLQRLRGLGDRA
>A0A849R4J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanophagales archaeon|TrEMBL
MGDEVYSDLMRELKAGEYVFTGELEPEKAGDVNEPIEMARELVGMVVACNVTDNPQSFAY
VNSMAASYLIQKETGMECVYQLRCSDRNRMALLSDVLGAGALGLKNILALAGDHVSLGDT
PDAKPVFDLDSTTLIKLIRTMVDDGKDLGGNEIHNPPKLHVGGAAAPGAAHLKAEVGKVK
RKINAGVEYLQTQVVYYTDVLDKFFGELGKVDVPILVGIFPARTFGQADFFDKYVAGVDV
PPDYLEAMRATKAIKDKEKKKEEVDRVNIEFFTGFLEHLKGTPAAGCHMMAVGYPRIIPP
LKKLME
>A0A3R7E2I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanophagales archaeon|TrEMBL
MGDEVYSDLMKELVEGKYVFTGELEPEKAGDVHEPIEMARDLKGLVVACNVTDNPQSFAY
VNSMAASYLIQKETGMECVYQLRCADRNRMALLSDVLGAGALGLKNILALTGDHVSLGDT
PNAKPVFDLDSTTLIAMIRKVVDEGKDLEGNEIHNPPKLHVGGAAAPGAANLKAEVAKVK
RKIKVGVEYIQTQVVYYTDVLDRFFKELGKVDIPVLVGIFPARTFGQADFFDKYVAGVDV
PPDYLEAMRKTKEIKDKEKRKEEVDRVNVEFFTEFLEHLKDTPAAGCHMMAVGYPRIIAP
LKKVME
>A0A2V8L5E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MQDLLTRLENHVLVCDGAMGTMLYSKGVFISRCFDELNISNPELVREVHLDYIKAGADII
ETNTFGANRTKLMTHGLADQIRHINIQGARIAGDIAGDNILVAGAIGPLGIRIEPWGKTA
IEEAQVTFREQAKALVDGGVHALILETFFDLNEVYAAIRGVRDVTDQPLIVQMSIEEDGN
SLEGTPPEVFAKRLEEWGADVLGLNCSVGPQIMLDAIERIANVTSKKLSVQPNAGKPRNV
EGRNIYLGSPEYMASYAKKFVQYGVRIVGGCCGTTPQHIKAIRAAVKSVGVAVLGPSPGA
SRRPLPAGEGTEGESSIPLESRSRLGRKLATKEFIKIVEMIPPIGHDFAKAIEKAKYLQA
QDVDAINVPDAPPSSARMSAISLAVLLEKSTEIESLAHYTCRDKNLLGMQSDLLGAYALG
LRNLLLITGDPHQIGEHSDATAIYEVDSIGLTNMVSRLNGGVDVGGKSIGKPTGFVIGVG
ANPGAMSDLELKRFFYKVEAGAEFVLTQPVFDATVLERFLDRAGNSKIPVIAAIVPLPNY
KTAEFLNYEIPGCSIPDSILERMREAQSKSPEHARNEGILIAQEILERIHGTVQGVQIRG
PFDRYETPVEVLSVMMKGATR
>A0A2V8IAC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MARNPLRECLQSRRFCHVVEIVASRISREARLLEVASQLATTPGVVAGSITSYAGGAPGQ
DPVRVGTAARARGLTPNIHVTCVSKDRQELRHYLETIAGLGLENVFALTGDYPKGANAVF
DLDSVQLITLMNELRRQGLPFWIAAAVSPFKYTEPDCAYQYLKLEKKFTAGADYAITQLG
FDVRKFRELRRYLDERNIQNPVLGNVYVLGLKSAERMSKGEPPGCWVAPELVEKIRDEVK
AKDRGEAARLERAARMIAILRGLGYAGAYIGGTHNAEHLSWIIERGQILAPRWEELAEEF
THAPKSAFYMFEPGPAAPRKLRGLSDRAVNALWHLLSPTQIPR
>A0A239EMI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas delhiensis|TrEMBL
MSSQERRFSFEFFPAKTEAGHEKLLATARQLAGYKPDFFSCTYGAGGSTRDRTLVTVLQL
DGEVGIPTAPHLSCVGDTKAELHALLAHYKDAGIQRIVALRGDLPSGMGMASGELRYANE
LVEFIRAESGDHFHIEVAAYPEVHPQARNSEHDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAQKLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIASIQSF
GEQVITEMCERLLDGGAPGLHFYTLNQADPSLALWKNLKLPR
>I3UTZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida ND6|TrEMBL
MQLAVRRLLPEERLMSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGG
STRDRTLNTVLQLESEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSG
MGMASGELRYASDLVEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADS
AITQYFFNADSYFYFVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQL
EAYADDTASIQAFGEEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A4Q7VLK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylomarina subtilis|TrEMBL
MKVIDHINQAIENKTTHFSFELLPPRKGNSIYKVFNTIDKLREFDPKYINITSHCDEVIF
AEAANGTFQKLLINKRPGTVAVAAAIKNKYKVTVVPHVICQGFTPEETENALIDLNFLDI
QDLLLLRGDSSRRHEFSTRESGHNYAIDLIEQVNQVNRGEYLDGTHTEAFETPFSYGVAG
YPEKHEEAPNLDSDIYYLKKKVDAGAEYIVTQMFFDNQKFFEFEKKIRAAGITVPLIPGI
KPISALSQLNLLPQVFKVDIPEALAAEVRKCKTNEQVQALGTEWAIHQSKELVKHAVPSL
HFYSFMASNCVRDIAKAIF
>A0A2V8K370|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MLVVAGDIAKPSGQLSNALQILESGLLEKHGIRTVGVAGHPEGHREVGDAVLRDALKRKK
VYAEQSGASVYIVTQFTFSAAPIIAWEASHRDEIGRLPITAGLPGLATARTLLKYAVECG
IGASLEAFSKRYDSLTKLLTMSAPDETIVELVRYKERTPLSRIAGIHFFTFGGFEKTAAW
VNQVASGNFEVTEDGKLVLI
>A0A6A0IPP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKKRDIRERLAGEVLLADGAMGSLLVSRGAPPDSPRSPICLTTASLVREIHDDYIGAGAQ
ILTTNTWDANRVKLARFDWADSLEKINRAAVRMAHEAAEGEYVYVAGDVGPLGELVKPYG
TLTKAQVRELFAEQIRILLEERVDLLLFETFSSTLEAVEAVRAARELSAEVPILASMTFL
ADGKTPFGADAAEALQALHDAGADVVGMNSTIGPQESLEVFQRVVPYVPAPVSVMPTAGY
PWLVAGRMVYPATPDYFRDLAREFVKGGVAVLGGCQGTGPEHVAAMAREVVGKPRRHVAH
LEAAVPAEVPPQVAPGLETSALKRRLADPEAFVVTVEIEPPRGTDASAAVDGARLLKGFG
VDGINVTDNPMARLRMSSIAVAHLVKKETGAEAVFHYSPRDRNVLGIQSDLLGAAGLGIK
ALLVVGGDPLKIGDYPQGKHVGEVDTLGLLRIVKGLNQGVDMAGGPIGSSTSFAIACAAN
PAAPGLDVEIQKLQAKVESGATFAQTQPVFDPAALDRFYARPESRLIPVLVGLVPLKSLK
QALYFANEVPGMHVPETAIARMRAAAEKGPEFEREEGVLLAIELARAIAERARGLHLMPM
ARYDVVKRILAELPARGRAEGSPAGGGR
>A0A2V8V198|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIKELLTRGRPTFSFEFFPPKSDEAARQLEQTITELQPLKPSFVSVTYGAGGSTRERTI
EIVTKVKRETGIEAMAHLTCAGSTREDLKGVLGRIRDAGIENVLALRGDPPKGQTGFTPV
EDGFRYASELVRFIRELHDSVMCLGGACYPEKHPECGNPAVDLANLKNKIDRGLDFVITQ
LFFNNQHYFDFVQRARRIGIQVPIIAGIMPITNASQIERFMVSCSATIPFELAEELDRRR
DNPQAVMELGIAHATAQCAGLLDGGAPGIHFYTLNRSTATREIYAALHAAGYTG
>A0A3N5GD93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MDFVSNRPCELSFEFFPPRTPEGRASLSAAWHQLADLEPSFFSCTYGAGGSTRDRTLGTV
LAIQSAGYRAAPHIACLGLNRADIANMLELYRDNGIDHLVALRGDLVAGVASAGDLRYAN
ELVAFVRETTGTHFRIQVACYPEFHPQACSPQDDLLNFKRKAEAGADSAITQYFFNIDAY
LRFVDDCDALGIHLPIVPGIMPIGNFAQLARFSDTCGAEIPRWLRLKMQSFGDDLASIRS
LGLDVVTELCDRLLSEGAPGLHFYTMNEAGLAMTICQRLGIGRPCLPLASQMVPA
>A0A258JWU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azorhizobium sp. 35-67-5|TrEMBL
MTSPIRASRETSRPPVRVSFEFFPPKTEEMERTLWASIDRLAPLGPSFVSVTYGAGGSTR
ERTHATVERIARETGLAPAAHLTCVAASRAEIDEVVRDYAQAGIRHIVALRGDPVTGVGT
AYEPHPQGYAHACDLVAGIRRLGDFEVSVSAYPEKHPESPTLDADIDYLKRKVDAGATRA
ITQFFFENDVYFRYLDKVRAAGIDIPILPGILPVTNFKQAANFAGRTGASVPAWLLKRFE
GLENDPETRKLIAAAVAAEQVTDLVDRGVGDIHFYTLNRADLVYAICHLLGLRPGAAETP
AQRLAG
>A0A1V3TU99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurellaceae bacterium 15-036681|TrEMBL
MSYAKEIDLLNQSVADLNGKVNVSFEFFPPKTEKMEETFWDSVHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKRVQQETGVVAAPHLTGIDATPDELRVIAKDYWDSGIRSIVALRGDEP
AGYDKKPFYASDLVALLKDVADFDISVAAYPEVHPEAKSAQADLLFLKQKIEAGASRAIT
QFFFDIDSYLRFRDRCATVGIEAEIIPGILPVSNFKQLEKMAKITNVKVPSWMHKLYDGL
ENDPTTRNLVGANIAMDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGLRP
>A0A2V7YKW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKVTEHLANADHPLISFEIIPPLRGGDVKGLLNLIEDLCKYRPPFIDITSHAAEVMYDET
PAGIQRRVKRKRPGTLGVCALIQNKYHIDAVPHILCQGFTREETEDFLIELRYLGIDNVL
AVRGDDSGFQKPLQYGRSANRYACDLVAQIAAMNRGRYLEEDLLDAEPTDFCVGVGGYPE
KHFEAANLMLDVRRVKEKVDAGAHYVVTQMFFDNRHYFHYVDLCREQGIQVPIIPGLKIL
NGEKQLASIPRNFYVEIPAELADQVLADPEHVGDIGVEWALKQSQELLDHGVPSLHFYVM
QSASAIKKLMARLKL
>A0A1E9PGG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aerococcus sp. HMSC062B07|TrEMBL
MKTKELFKGKTLFTYEVFPPNAKSSSASIYKTLDGLKELDPDAISVTCGALGSDNRLKSI
EIASLIKNYGIESVIHLPCLYETRASIDEKLAELKAANIENILVLRGDPKPGQSPKEDFP
YAADLIRYIKSKEDFNLIAACYPEGHVDAPDPITDIRYLKEKVDAGSDQLISQLFLDNDY
FYRFLERADLAGIDVPIEAGIMPVTNKKQIESMARICGVQIPDKFRRAMEKYQDNPLALR
DAGLAYAIDQIVDLISHGVDGIHLYTMNNPYVARYIYQAVKNLL
>A0A3N5JNV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MRTFRDAIRTRPFTVTADLALDRTTDAAAVRRQARLLAPLVDAIQVPDAHDGRLQMSGLA
AAAILLGEAIDPLVHLTGRDRNRIALENDLLGLGALGVTSLLLTRGEELPAGYKPPTRQV
LELSGEDLVTTAVQLGEDESIRAVPGFCVGTAATVFAPKAGWTPKSLLARVDAGVAFVQT
QVCFNMKALRRYMEHLVSARLTWRCAVVVSLAVLPDAASARLLRQHLHGTVMPEKLVQRI
AQAADPELEGIRVCAEKIQRLREIPGVSGVNLMTPGPAELLVEAISAAGLADPAAKITH
>A0A3N5PQJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MTNDQLKAHISAFLRDYSIEITPHDAEKLDAIRAELKEGTAVYVAHPPGVPIDDIVTLAG
RVQKLGLTATPHVIARKLESRDQLDHALARCQELGIKNALCVAGDITADKPAYDSSLEVL
QTGLFKKYGFREVGVAGHPEGSKAIGEERVEQALRGKAEFAKTAGFDLYFATQFGFDPQP
FIDWEAATAAKGIHLPIHVGMPGPASLRQLAKFAMLCGVGASMRMLTSRASAMANLLSTQ
APDEMVTALARHKGENPQSRFKRVHFFAFGGVVKTARWANAVISGRFVLNNQATGFRVED
VN
>A0A226BXT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natranaerobius trueperi|TrEMBL
MKGGDHFMKISNIYSKTNRPVLSFEIFPPKRKKNQTRKDFDTLLNTVDKLTTLNPDFISV
TYGAGGTDSEGSFKVSKYIKDKGVVALPHFTSIGYPSQEINSYLEDLGQDGFANILALRG
DLPKEPSKADMVWKDFLHATDLIKIIKKEFPRFCIGGAAYPQGHQESNYDGKDIEVMKLK
EEMGVEFFLTQLFFDNDKYLRFVETVKNHGVTAPIGAGVMPLMSPKFVDKILKLSGATLH
KELHQTLDKYRDDEEEFLKRTIDFCIRQVNDLIERGVDGIHLYTMNKYHPVKKIINNLDI
KTAVNT
>A0A3N5KIR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MPPVTVSFEFFPPGDPQMEQVLWSSIQRLAPLAPRFVSVTYGADGSTRERTHNVVTRILQ
ETPLTAAPHLTCVGAPRDEILEIARAYRDAGIRHIVALRGDPPAGQAAYVPHPDGFPYAV
DLVAGLRRIADFDISVAAYPEVHPEASSAGADVDNLRAKLDAGASRAITQFFFDTDAYLR
FRDRCAAAGITAPIVPGILPITRFPQMLRFAARCGANVPDWLAHRFDGLDDDPETRRMIA
ASFAIEQVRRLQEHGVHEFHFYTLNRAELTYAICHALGVRAPAARTTAED
>A0A0B4E0K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hominis|TrEMBL
MTASLRLHEATRRCPKRMIHGPCGGVTIDGGCEVPGIRCSFVDEAAVLRHLEFSTAEVDA
PDAARGSGDALPVLPRGEASTAFAALVEAGAVITADLPVRSVDPAVITEAGVRLRELTAV
IAGEPPGVREALSPTHKALLLAAAGSRVVAGLTCRGRNRVALEGELAALADLGVSGVLAV
TGDHPASTALPHAQPVFDFDATRLAALARRAGLFVAVAEQPSAPPVDYRPTRLARKAHAG
AELGILNLCGDLAEIRRFTAALATTATPVPVLVSVPVLTSAATTRRLAALPGVGLPDELV
MAVAGADDPGESGIAAAVAWAHRALAIPGVVGVHLSAIAAGATEPPDRADAAELAAVDAL
ASAAARLRAVIAAETASIA
>A0A3N6BGK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MAIRNKAKFLRDCCDGVNLTDNQTAIVRMSSIASGAILVQEGLEPIIQMVCRDRNRLAMQ
SDLMGAYALGIRNVLCLTGDHQSFGNHPTAKNVFDLDSIQLVRMVSGMRDQRVFQCGEAM
KGQEPRLFVGAAESPFAAPVAFRPYRLGKKARAGANFIQTQLVYDVEAFETFMETVRKLG
VHEQTYILVGVGPLKSPGMAKYMKESVPGILVPDQLIQRMNKAGAQWAGRKAEELSKEEK
KARSEAWKAEGIKICIELIQKVRAVEGVAGVHIMAIEWEEAVRPIVEGAGLLPRPKVTEA
TS
>A0A066RJL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium galatheae|TrEMBL
MGYAYANHLDALNQNIADLNGAINVSFEFFPPSTPAMEETLWSSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLIAAPHLTCIDASRDELRTIARDYWKNGIRNIVALRGD
LPPNGGKPDMYAVDLVKLLREEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVVNMKQAKRFAQANNVKIPNWLEKQYQ
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRADAEATV
>A0A497EF68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKVTDHLDRATRPIISFEIIPPVRGGNFGDLTDLIEDLVRFEPPFIDITSHAAEAIYEET
SAGIKKKIKRKRPGTLGICALIQNKYNVDAVPHILCHGFTREETEDVLIEFRYLGIDNVL
AVRGDTLDYKKTIEGHRTINRWAGDLVQQIANMNRGAYLEDDLLDADASEFCIGVSGYPE
KHIEAPNLKTDLQRTKAKVDAGAEYIVTQMFFDNRHFFEYEKRCREIGIDVPIIPGLKIL
SSKSQLTSIPGTFHIDIPADLSDEVMAAKDAHVSGIGLDWTLRQAEELLSRKVPALHFFV
MQNSRTITKLLDRLQP
>A0A2V9I5Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MGLASQTGASLLESLKKGEELFSAELRPPRAHSPGLQSMDDWIDTYHSIRRLNVAGFHVF
ITDNAVGRAEEENLRHLVTNLGPDARRSHIIPFLTSKHPLDYCLRYAERAYEQGFRTLVV
VGGDRHDGIPRCVEHAIQLRRIIRRSVPSLILGGWANPHADLSEQTDYLMRGREETDFFL
TQVVSHHDAEAVERFLELIGRRGIEIPGIFGVFYYRSARKSSLDTLRRFFPVPVREIEKE
FEVEELRADDVCARTIRKLRRLGVRRFYVSNLPVADAAARLQTITGLAAEGEGGG
>A0A5P9YNU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea nitratireducens|TrEMBL
MALGRPSVLPDRVPTVRDLLAAGGRSFSFEFFPPKTDEGARQLWKAIRELESLRPTFVSV
TYGAGGSTRDRTVGIVERIAHDTTLTPVAHFTAVNHSIRELRHLVGRFADAGVRNILAVR
GDPPGDPMAEWVQHPDGVLYSEELVRLIRQAGDFCVGVAAFPYKHPRSPSIDADTEYFVQ
KCRAGADYAITQMFFRAEDYLRLRDRVAARGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPEVAARFEEVADDPEAVRRLGIEHGAELCRRLLDEGAPGIHFITFNRSSASREVFQRLN
VPSSVTAGPAGRHPLPVAGGLQGDAR
>A0A7W1XRU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoactinomyces mirandus|TrEMBL
MSKPELLHRLQDSLLVGDGAISTYLYQQGVSVGHCSEELVLSNPSLVSDVHQAYYEAGAR
VIETHTYGANRERLTRYGLETRVTRLNREAVRIARESVGSDAYVVGAIGSICAGRVPVYD
KEEYRGMYEEQAIALLHAGVDGILLETFLDLKEILLAVEVIRPLTPLPIFAQLSMIELGR
TRDAFTLSEAFAQLAEKGVNGVGINCRLGPVEVLRTLEKTIVPGDLIITAYPNAGRLGMS
NGELHYKSTPDYFEETAELLVRQGVRLLGGCCGTTPEHIARIAMVLRDMTPVERENPSSD
GWKIPPVETIVVQKRKKPTVVEQVRKKRTIICELDPPRDLDISRYLEGARRLQQAGVDAI
TLADNSLATARMSNLALGAILKKYGIEPLAHVACRDRNLLGQQSHLMGLHALGIDQILVI
TGDPSRMGDLPGASSIYDVTSIELTRMVKQFNEGISFSGRELKQKAGFVVGTAFNPHVRK
LDAALKRLEKKIEAGADFVMTQPVYDPDGMLEVHEVTKSLPVPVFIGIMPLTGYRNALFL
HHEVPGIKIPDQVLKRMEKTTDRLSGQREGMQVAKELLKVAMEKFAGIYLITPFSNWHMT
EELTRFVREHDRQLLEHYHHA
>W7WGF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylibium sp. T29-B|TrEMBL
MSDTPSLKLPVPVSFEFFPPNTEAGSEKLKTVVRELGSAAPEFFSVTYGAGGSTRDRTLS
TVRDIAALGFEAAPHLSCVGSTRAGIAEILASYRAQNIRRLVALRGDLPSGTATAGEFRY
ANELIAFVRETQGTDLRIEVAAYPEYHPQQRYARRDLQHFANKMKAGADAAITQFFYNPD
AYFHFLDEVRALGVDAPIVPGIMPFHNYARIAQFAMRDGIEIPRWVALKMEGYMDDAASI
RAFGIEVVSRLCERLIAGGAPAIHFYTLNQSALTLEVCRRLASARG
>A0A166K5Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nodularia spumigena CENA596|TrEMBL
MQDTQNPTVLNSFRRAAQAGEFLVTAEVAPPKGVDVTHMISMAATLKGRVHAVNITDGSR
AVLRMSSLVASVILLQNGIEPICQVACRDRNRIGLQADLMGAHALGIRNILALTGDPVKV
GDHPHAKAVFDLESVRLLQLIRKLNQGVDDNEKPLPDGATDLFAGAAVDPQSDSWSGLQK
RFERKIEAGAQFFQSQMITDFERLEKFMDTVAVNYEKPILAGIFLLKSAKNAQFINRYVP
GVNIPQHIIDRLAQAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIAPILDLAGV
TPVTNVN
>A0A4U3KUI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ilyomonas limi|TrEMBL
MKITDHIQQATDTLISFEVLPPLKGRSITSIYDHLDPLMEFKPSWINVTYHRAESMFKKK
KDGSFEKVEVRKRPGTVGICAAIMNYYHIDAVPHIICGGFTRRETEDALIDLNFLGIDNV
LVLRGDAPKNEAFFEPEPDGHRYGLDLLKQVVNLNNGIYIDEDIRDGGKTDFCIGVAGYP
EKHFEAPNLEVDMKRLKEKIDTGANYIMTQMFFDNKKFYDFVKACRAMGINVPIIPGLKP
ITTRKQLSVLPRIFHVDIPNELSEEILRCKNDEDCEKVGVEWLIQQCKELKEFGVPVLHY
YTLGKAKTIFNVVKELA
>A0A1A2PIW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. E1319|TrEMBL
MMSADSDCPKRMEFGPCGGVRPDGQCEMRPGACAFEDIVPWPGPQPPPRPARAPLVLTDF
SCTPFDRADVAATAGLLAPGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVAPWITLSCRDR
NRVVLEQELRGLRSIGVETVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGVVPAV
PETPTAPPVRGRPARLVEKQRAGAGLAVLNHVPFPDMVADFMAAALAGGLTIPVIAAVAV
FTDSVSAAVLEGLPGLELDAAVTQRVLGAADPVSAGIAAAVDEARALLSIEGIEGVNVSG
LASASGARVGAEIKAEVGRRIRVEAL
>A0A6C1FFJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola subsp. Uroleucon sonchi|TrEMBL
MNILSEYYQDIINQKTENIKNSIHCSFEFFPPKNITLEENLWSVIRKIVKLKPKFFSVTY
GANNGECQKTYNIVKKIREKTGIITAAHLTCVNSTPGKLKSIAEKYWNNGIKNIIALRGD
AIKKNYKHTMYASDLVILLKKIADFDISVAAYPELHPESQNSKEDIINLKKKIDLGANRA
ITQFFFNIDFYLKFRDNCIKNGITVEIIPGILPIYNFIQLQRFLKMTNVQIPKWMFEIFN
GLENDIFTQKIIGASIAIDMVKKLSSEGIKNFHFYTLNQSDITYSICRILGL
>A0A4Y8KDW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Hb1|TrEMBL
MSACNARPAFSFEVYPPKSVAAASALARTIDHLAAAGPEFISVTYGANGSSRNSSLDVLR
YIKDHTSVDAMAHLTCVGSSHADASRLIREFLDAGIDSFLAIRGDAPQGTVEGDTTFLGD
LHSAGELVQLIHRVQTERVPYTETVIPGLPGARGVKTERSKVRIGVAAFPNGHPNSRSIA
QDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVFFPILPGIMPVTSPNRLRRI
LQLSGEKLPAELSIELEVEPTEEGQRQIGIDYAVRLGQDVLAGGAPGLHLYAFNQHDTVL
SILEGCGARPVPAAMP
>A0A4R8RQ17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum trifolii|TrEMBL
MDKITDKIAALPADANYFSLEFFPPKTQMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRTLIDKALEDAKALGIRNILALRGDPPRKDE
YRTADDSDVEDMDDFVWAIDLVRYIRKKYGDYFCVGVAAYPEGHADESHPLGQSFEHDLP
YLVDKVQAGADFIMTQLFFDIKAYDNFERVLREHPSGAFKTIPLLPGLMPIQSYQMIKRT
TKLSHAKVPADLMARLDAAKGDDERVKRVGVDILSELVQQVREVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDADEDEEAVIDDAIGVPTVQLNGLSPIPPSTPRTFSGRRQSSIG
SDPHNRVIVSSASNPAYETTAASLSAEPVNTRANTLAISEGEGVLGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHMSVTQAVGLWGTPKTVQDVNNLFIRHIKGQLSAIPWSEEELL
PESNIIQQELLGLNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVEFFLPSAD
WASLVARLNEVTDNTICFYAANAAGDFVSSDASGGLVLEGTECSTNAVTWGVFPGKEIIT
PTIIEEVSFRAWADEAFKIWGEWAKVYGKGSESEALLERIQSDYWLVNVIHHDYVERDAL
WQLLNGEKET
>A0A826HN34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis Bt407|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8E4AVD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii|TrEMBL
MMIAPQSESREEALLADLLSHYSIEVTSRDLQSLESMTATLPQGCEVFIAHLPKEDIGLL
VRAAAGLRDAGFVPIPHIVARNIRNRLELDTMLARLSEEAGVRHALVLGGDRDDAAGAFG
SSLELIETGLFQAYGIDRIAIACYPEGHPRIAGAILDAALTAKIDAAARAGLDVLLVSQF
LFDPKPLLNFARRLRERGVTAPLSVGIAGPASRTKLLKYALRCGVGASLRALRERSEIAR
NVLSGETPEELLMEIAAAQATEPDLGISGVHFFTFGDPAQSIRWAEQQVDR
>A0A3R6Q4L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF12-28|TrEMBL
MNLREYLKTTNLITDGAFGTYFAAKYQTQDIPELANITAPEKVKKIHEEYLNAGAKFIRT
NTFASNKETLQEDFAEVEKNIQAAVEIARDAVNGRDAWIAGDIGPIPVNGTEDAAAAADE
YYQIAKTFAERGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIAAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIREMSSWDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLSVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTEEDAARLRRIKDETGATILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>A0A7K3UHT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium phaseoli|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLAQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAIGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGFSRRAAKSAGAAA
>A0A7U8PLN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella abortus bv. 3 str. Tulya|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>C0QAY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforapulum autotrophicum (strain ATCC 43914 / DSM 3382 / VKM B-1955 / HRM2)|TrEMBL
MRVGNLYKNQSDPSVSFEFFPPRDDKAESSFYGVVDALSALNPAYMSMTFGAGGSTSEGS
FQAVKRMMIEKNLPMVAYIAGYGLGPHEITEVLDRYKALGVETIFVIRGDKPRTDGFTPH
PESFAHASDLIRFISDRYDFDLGCAGYPEGHVQAESLEKDVEYLRLKQDNGAQYVVAQYF
YDNDSFYRYVDLCRKSGITIPIIPGIMPIYTVKLTRMLCKLCGSTLPTGLREKLDSLTND
KSEAVADLGVNFAFDQCRDLVLKGVDGLHFYTMDRSGSVLKIVQRLKDDGLFK
>A0A366DLU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia puris|TrEMBL
MPFSVEFNPPRDEAGEARLWRAVREFERMHPAFVSMTYGAGGSTKDRTVRVTGQLARETT
LLPVAHLTAVGHSVAELRSLVGAYADSGIRNILVLRGDPPGDPLGEWHRHPQGVEYAEEL
VRIVRDLGDFHVGVASFPQGHHRSPDLDTDTAYLTAKLRAGAEYSITQMFFDVEHYLRLR
DRVAAFDPVEGAKPIIPELMPITSLRTVARAEELCGRPLPSAVLERLRRAAGDGPEENRA
AVRAAGIEIATEMAERLIEEGAPCLHFITLNFAKATSEVLTNLGYGVRAAPVSA
>A0A502LJS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus haemolyticus|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIESYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DEDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPS
>A0A177VDY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tilletia caries|TrEMBL
MPATTPPAAATPRGDDSWKITAKLAKAERENRIWWSFEFFPPRTAQGLNNLYDRIERMSD
LGPEFVDITWNAGGRSSDLTSSLVKTVHNYFGLETCMHLTCTNMPREKVDTALKDAKEHG
CRNILALRGDPPAGESQWEAHAAGFTCARELVEHIRAQYGDYFAIAVAGFPEGHPESTEG
REKELEHLKAKIDAGADFIFTQMFYDFDIFAKWVKEVRAAGITVPIIPGVMPIQNYGGFE
RAVARFRTFVPQYFHDALEPVKNDDQAVRDVGTQLVGDMCRKILESDLGIRGLHIYTMNL
ERGSRMLLDYLGLTPSVNQIKQLPWTPSLTPKRREEKIRPIFWANRAKSYLSRTETWDEF
PNGRWGDARSPAYGDVNAYGVSLNLTDAEARELWGAPESLDDVKALFQKFCSGDLKALPW
SDTPVAKETSVIGSQLEKLNGRGFLTINSQPAVDGAPSDDKVHGWGPSNGYVYQKAYLEC
FVAPERLDEVIAHFDRNPQITYHAVNAQGDMRTNTQSDAPNAVTWGCFPHSEILQPTIVE
SISFLAWKDEAYELGRKWATVYEPSSPSRKLLQGLFDSWFLINVVHNDFKQPDAIFKVFE
SLGAETNGTNGHA
>A0A151N4A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alligator mississippiensis|TrEMBL
MRRRQESGDRWFSLEFFPPRTANAAVNLISRFDRMAVGGPLFIDVTWHPAGDPGSDKETS
SMVIANTAVNYCGLETILHMTCCSQTKEEITAHLHKAKHLGLKNIMALRGDPIGEEWEEE
VEGFNYAVDLVKHIRCEFDDYFDICVAGYPKGHPDAESYEADLQHLKEKVCAGADFIITQ
LFFRSETFLQFLKDCQAIGITCPVIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIK
DNDAAIRNYGVELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKHLGLWKEDPRRPLP
WAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYL
KSKSPREELLKMWGEELTSEESVFEVFTCYISGEHNKNGHKVTCLPWNDDPLAMETNLLK
EQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLRV
LRKYELRVNYHIVNARDENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKGEAF
ALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLDNCLWQVLDDTFELLSAPTQ
C
>J1I5P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospira grandis DSM 2844|TrEMBL
MKVSEHFRQAEGQSLISFEILPPLKGRGIQGIFDTLDPLMEFKPPFIDVTYHREEFIYKR
RPSGYYEKTAIRKRPGTVGICAAIMNRYGVDAVPHLICGGFTADETENALIDLMFLGVDN
VLVLRGDPRKFETKFMPEEGGHAYALDLVKQVQNMNEGHYLDSTLMDAQASSFCIGVAGY
PEKHFEAPNLDMDLHFLKQKVEAGADYIVTQMFFDNQKYFDFVDKCRAAGINVPIVPGLK
PITKKYQLNAIPRHFFIDLPDDLAKTMMEAKDAEARRQVGIEWCVMQSKELKAAGVPCLH
YYTMGDVDTIKSIAEQVV
>A0A1X0VBW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc pseudomesenteroides|TrEMBL
MTKINQIYKTKPVPVLSFEVYPPHQEESVKSLFQTLEELNPRQAGVDFISVTYGAGGSAN
HELTQHIASYIQNHFGVTALHHLTGINQTPATLHHHLSEMKAAGIENILAVRGDLPSSDY
DNSCYPFAKDLITDIKKENSFSIGAAVYPEGHVDNPITGISVGGVREKISAGSQFLISQL
FFDNNAFYKMQEELKNNYIQIPVSAGILPIISQKQVEKLTYMIGSSLPAKLAKIVHKYQD
NPEALRQAGMAYAMEQIYDLLDHGVDGIHLYAMNQADILTTMLPKINDYIQCKNKRYAV
>A0A1V5W089|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium ADurb.Bin218|TrEMBL
MHIREILEKHKISFSFEFFPPKTEKGSEALFKTINELVPLNPAYVSVTYGAGGSSRDLTH
DLIVKIQNQTNLTVVSHLTCVGSTKEEIHNILSRYRENNIMNIMALRGDPPAGESKFKKV
EGGFEYACELVEFIKKHFPYMGIGVAGYPEGHPETPNRIKEMDNLKRKVDAGADYICTQL
FFDNNDFYDFRERCEIAGIHVPIIAGIMPVTSIKGMYKMAELALGTRIPAKLQRALLRAE
DDSYVEKVGIHWATQQVYDLIDNGVKGIHFYTLNQSKATREIYASIGISNSESLNK
>A0A429FNU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. WAC 04182|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPEGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTLRTLRTSIKLSGAPTAPRRLLDRLEPL
ADDPKAFRAEGIDVVTELCERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>R6WRA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea sp. CAG:317|TrEMBL
MMIRDLLKDKNPHISFEIFPPKTDAGYESVLSATNKIAALKPSFISVTYGAGGGTSKNTV
SIASHISNDLGVTSLAHLTCVSSTKEEVHQVIRRLKEQKIENILALRGDIPSDDSFPLPN
QYRYASELIEDIKKEGNFCIGAACYPEGHVETEHKKDDIANLKKKVDCGVDFLTTQMFFD
NHILYNFLYRIREQGITVPVLPGIMPVTNGKQMKRICSLSGTILPERFRAVLDRFGDDPA
AMQQAGIAYATDQIIDLIANGINHIHVYSMNKPEVAAAIMDNLSEIVKR
>I3WHU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum BGN4|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIANTIH
GEYGIPAVAHLTALYSDEAKIDEALDMFEAAGVSAVLALRGDYIDGEEPVGRFNHASDLA
AYIHDRKPDLKVFGACYPEGHYSAASLDEDIGNLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGAKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGII
YASDQIADLVAHGVDGVHLYSMNHPATTRRIWHNVEPLFTVE
>A0A7U4CQ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio anguillarum M3|TrEMBL
MIDWRKNATGRNKMGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSAQMEETLWNSVHR
LKTLQPKFVSVTYGANSGERDRTHLIIKEIKEQTGLIAAPHLTCIDASRDELIQIADDYW
HNGIQNIVALRGDIPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQSDLV
NLKRKIDAGANRAITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQASRFAAQN
NVKVPGWMAKQFNGLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALC
HTLGVRPKA
>A0A7C7K9Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterales bacterium|TrEMBL
MNRNQKEFNIKKLLNNYSIETTPNVYEKYGKFSDLISTDNAVYVTYLPDENSSRVINTAK
KLTNEGFDVIPHLPARTIKDNNELEKYIGDLSEKAGCNKILVIGGGSNQKGNITSSLDIL
KTDLLSKYQFKEVGLAGHPDGNPDISEEELDKAIIEKNEFVKNVDYKAYLATQFFFEVSS
LEIWEQKLNLHNNKLEIHAGIPGPATLKTLIAYAKSCGIGNSIHFLSKQARNITKIMKTR
TPDKLIADLADYKEERPNSKLAKLHFYAFGGIKTTSEWLYDVINSNL
>A0A1R1E078|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus amylolyticus|TrEMBL
MKADLRKVMQERVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQISALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GEFRYGATPEYFGQTAVQFAELGARIIGGCCGTTPDHITAMKEALADYVPSLILEPDPSE
SKPRIVLHEKVDERSGRGGQPTIVDLVKHRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALSINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLEKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A1Y3D5L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4648|TrEMBL
MTKRIPISFEFFPTKTDVGAEKLRVVHQELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYASDLVA
FIRQHSGDHFHIEVAAYPEMHPQAESFDKDIQNFITKARAGANAALTQFFFNPDAYFYFV
DRLQKEGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHVEPNRQIVLDLGLA
>A0A0S9CKZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf231|TrEMBL
MTFSVNQLEEARRVHADGESAVALGAPLYADVGGDVDVSFEFSPPKSDKAEENLWQSIET
LCPLNPRFLSVTYGAGGSTRDRTHATVARIARDTDVPAAAHLTCVEATREEIDAVAQEYW
AAGVRHIVALRGDPPAGAADYAPHPGGYENAAALVAGLRRLHPFEISVAAYPEMHPNSSD
LAADLDNLKRKLDAGANRAITQFFFEAETFFRYRDAAAAAGITAEIVPGIMPIGSFAGVQ
RMAAMCNTDVPGWLARLFEGLDDLPAARQLVAATVAAEMCRKLYAGGVKQLHFYTMNKAE
LSFAICHLLGARARPSQGRVAA
>A0A1B7SC04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ogataea polymorpha|TrEMBL
MSLLGPLFVTVTWGAGGTTAHKTLDLAVTCQEELGLTTCLHLTCTNTSKEVIDDALERAK
KAGIRNVLALRGDPPRDGMDPERNGHFKYAVDLVRYIREQHGDYFCVGVAGYPEGHVEGA
DNSDQDMKKDLPYLVEKVNAGADFLVTQMFYDADKFVHYVKTVRSTEEIKNKDLIIIPGL
MPINGYSIFQRASKLSHASIPEPLLEKFPEDIQNDDDKVKEIGVDVLSEMVSKIHQDTNG
EIRGFHFYTLNLEKSIAQIINKNELLSQVLKKKEEEEELEEETVSDEDIDEATTTAKRAA
YADRFRQVNNQVIVNAPMSRSGTRNSMSQVKTIVSISSGKGTLGKDATWDDFPNGRFGDS
RSPAYGEIDGYGPSLKMTSSKAYELWGYPESLKDISKIFTNYLSGKINALPWSELGLNPE
TALIQEELIRLNELNWFTVSSQPATNCSKSSDKIFGWGPKNGYVYQKAFVEMFISKKDWE
ALLPRLDANEYVTYYVSDSSGGYASNLPGQKSNCVTWGVFPDREIVQTTIIEEESFRAWS
DEAFNIWREWQMLYARGSVSHKLISQVLEQYLLVSVIHHDYPNEQALWELLLEE
>F1YUV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter pomorum DM001|TrEMBL
MSLSRLSVELIPRSAEALAADVATVKTTFPAADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQSGLEEILIVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMQGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLEANILFAQTVLKELAQEKGKAYLMPVRIKLEQY
LPALLDAVA
>A0A1Q6Q6A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. CAG:82-related_59_9|TrEMBL
MIDVRAHLARKPLLFDGGMGTYYKAKPGTECEQGNLLDPAGVRKIHREYLAAGAEAIKTN
TFGLPRMAAARQPDWQALARAGWKLAAEAAVETGAAVFADLGPAPDTEAAPAGSIYTAVA
RCFVEQGAKNFLFETLSSDAGVLEAVQAVKAQVPDAFVLVSFAVLPDGYTREGMYSKDLV
RRMTESGIVDAVGFNCVSAPGAMRTLVQQLGSTALPLSVMPNAGYPVVTRTQVKYQGKPE
YFAKELARIAAEGVRILGGCCGTTPAHIAALRAALDSLPAVEKAAPAVQVSTPEAPTVEK
DDAFLRKLNAGKKVIAIELDSPKDADLTNYLAGAKRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGLCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPMTVFGALNLNARNFEVELRRAGEKLENGMSGFL
TQPVLSEQAVENLRRTRETLGERAKILAGIMPVVSQRNAIFMENEVNGIHVAEEIIEAFA
GLDREQGEALGLEISLKMAREALPYADGFYLMTPFNRVALMERLIARLKTELLQEQ
>A0A8B2P9X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces badius|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKA
TQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A6I6YAW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus rhodochrous|TrEMBL
MDRLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERLGPAFVSMTYGAGGSTRDRTV
RVTGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWEK
HPEGLEYADELVRLVRDLGDFHVGVASFPEGHHRSPDLDHDTRYLVQKLRAGAEYSITQM
FFDVEHYLRLRDRVVACDAEQGLKPIIPEIMPITSLRSARRSLELSGSHLPPVLEERLRR
AAGDGPEENRAAVREVGIEVATEMCERLISEGAPCLHFITLNFARATGEVLDRLGYELEA
PAAVQPA
>A0A7G8YHJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas protegens|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLAGYNPDFFSCTYGAGGSTRDRTVNTVLQLE
NEVKIPAAPHLSCVGDSKDDLRGLLKQYQTAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A229NWX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus herberti|TrEMBL
MSSTLKDKLLRKESGILTYGMTPPKSSHPPEKIREIADKQISRLKDTGIDGLVLYDVQDE
ADRTDKDRPFPYLEALDPTEYYNGYLKQELGVPSIIYHCVASEGPDKLAKWILQDRDDQR
YTVYVGASSSRQQVQIRLPEAYRMSGILNEKLMTGGVVIPERHRSKGDEHMRAQAKQESG
CGFFISQATYDVEASKSFLSDYYYDSRKNGTEMVPILFNIAPCGSAKTLEFMKWLGISIP
KWLENELMHSQDILDKSVQLSRQVFLELYRFGIEKGIPIGCSVESVSTRKVEIEASIQLL
KDIRQDMQSLSEQLTVV
>A0A3P3UCK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus oralis|TrEMBL
MTLSLEKGRLSDDRFIVTAELIPPRSWNPQPLVEQAVRYRGNVDAVDLSDNLLAIARMSP
VVGAFFVRQVGVEPIVQINLRDRNRMGIQSDLMGLAAMGVKNITILGGYPAKVGTEPEAK
EVYDLQTMELVSRVRRFVDEGRLFDGTLMEEKPIFTIGTVENIAGKPIKELIDRLEAKAE
GGTDFVRTQLVFDMDLIGEWMEEARRRGLHKRITIMASILPLRDAAHVDTALRIPGIVIP
DAFKKRLVQSESQEEGLSLAAELIGKLRQIEGIKGIHIRPIGGAENSVNKVVQLAGLKDA
RAAEIGA
>A0A0N0ZX88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium indologenes|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVHQINDLGRGKYLHNEDTVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFENKKFIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAIAQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A411DN99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium indologenes|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWSIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A517YI63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anatilimnocola aggregata|TrEMBL
MTFYPPGKFTLSFELFPPKTSTAEAAMYDNVEHLMAFRPDVITCTYGAGGSTQQKTLEIT
SEVKRRFGVRVASHLTCVGATVNQLREYLQIAGDRGVDNIVALRGDPPKGETSFTPVEGG
LRYANELLSLIKADFPQYGVAVAGYPETHQEAPSFEVDLQNLQRKVAAGADVVITQLFYD
NADFFRFRDACGQLGIKVPIIPGILPVTNLGQIQRITSLCKAKLPAEFIAKLGEKDSPEW
QFDVGVEFATRQVQELIDSGIPGVHFYVLNKSPATSAVLQAVKYAS
>A0A1E4LKS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium SCN 68-20|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A5C7PNV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrionales bacterium|TrEMBL
MTTLNETSNLYKKIKNGEFVVTAELSPPKVPDLSRLDKHLAHYRRGVDAINVLDMPSATL
RMSSIGTAIYVKQQGLEPVMQMTCRDRSKLGMQADLISAYAHGIRNILCLTGDYVTFGDH
PMSKPVYDMDSTNAIMMVNQLRKVGKSYGGGAIADSAKEDPFKMQWCIGGAANPAGNKPE
HLARVMAKKAAAGVDFLQTQPVYDLEAFDKWWKALEREGVTKKVAILPGILPPRSHKGLA
FMMQHVPGIWVPPHVEKRIREAEDQKQEALDFSLETMRTLKERYPIAGFHIYPLAWTENV
PYLLGELGLLPPEGIAA
>K8XFN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus opacus M213|TrEMBL
MTRTPSIVDRIRSSSDGRVPFSVEFSPPRDEAAEARLWRAVREFERLGPAFVSMTYGAGG
STRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRGISNILVLRGDPPGD
PLGEWEKHPDGVEYAEDLVRLVRDLGDFHVGVASFPEGHYRAPDLAHDTRYLVSKLRAGA
EYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSVRRVLELSGSRLPAH
LEKRLATAAGDGPEENRAAVREIGIDVATEMSERLIAEGAPGLHFITLNFARATSEVLAR
LGDKVGSGVADPTPVTPARVS
>A0A1G7Z6D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas abietaniphila|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARTLAGYNPDFFSCTYGAGGSTRDRTINTVLQLE
KEVNIPAAPHLSCVGDSKDDLRGLLTQYKDAGINRIVALRGDLPSGMGMASGELRHANDL
VTFIREETGSHFHIEVAAYPEMHPQARNFEDDLKNFVRKANAGADSAITQYFFNADSYFY
FVERAEKMGVSIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIMAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1E4E8A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niastella sp. SCN 39-18|TrEMBL
MKITDHIEQAKGTLISFEILPPLKGKGIQSLYQQLDLLMEHKPAYINVTYHRSEHVFKKT
ADGNFQKVVVRKRPGTESICASIMNKYNVDTVPHLICGGFDINETEDALINLNYLGIDNV
LVLRGDAAKNEANFDPEPGGHRYAIDLLKQVVNLNAGLYLEEDLKNTSKTKFCIGVAGYP
EKHFEAPNMESDLQYLKQKIDAGADYIVTQMFFDNEKYFSFVKACRDLGITVPIIPGLKP
IYSIKQLTILPKIFHIDLPTALSNEISKCKTDLEVEEIGEAWLLAQSQELKKAGVPVLHY
YTLGRPHMVSRVVSKL
>A0A653Q0V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. 8AJ|TrEMBL
MSPPGLIDAHPQLSETAPVALSYELFPPRSPAAAETLWTTIRELETTEPDYVSVTYGASG
SNRDTALELINRLLVETTLRPLAHLTCVGNTPQELAAVIGDLLDIGVRGILALRGDLPQD
GAQPAAGSLRYAQNLIDLIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEDHDVEVLL
AKQRSGADFAITQVFFEAAQYENLLTRARRAGVSIPIIPGVMPFTSLRRLNRLGELAGVE
PAPRLMERLAAADNDIDRLHIGVDATVDLANAALDAGAPGLHLYTFNEHQSALEVLDKLA
LPRHNRSSHARAAVARPQLAS
>A0A519I7A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp|TrEMBL
MTAGNAQGTGFPVSLEFFPPKTPEGVEKLRAARQQLYALKPDFCSVTYGAGGSTQEGTFG
AVREILAEGMSAASHFSCIGATRESVREQLATLKAMGVKRLVALRGDLPSGYGSGGEFHY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPNADLQAYVTKVRAGADSAITQLFYNSD
AYFRFVEDAERFGANVPVVPGIMPIGSSTQLMRFADASGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDRLRSAGVPALHFYTMNQSTATLEICRRLGI
>A0A5B8CGH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium fuliginis ATCC 27551|TrEMBL
MTLSFPSVEEATRAWQAPLYADLTGDINVSFEFFPPKTEKMEEQLWSAIQTLTPLAPKFV
SVTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKAEIDGVADAYWEAGVRHIVA
LRGDPPEAGAKFEAHPDGYKGAAELVEGLVKRHPFEISVAAYPETHPDALSARGDIDNLK
RKLDAGATRAITQFFFEPDTFFRFRDTVAAAGIDADIIPGIMPVSNFAAVQRMSAMCNTD
VPGWMGKLFEGLDDLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPATLEKTA
>A0A4P7BHW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia plicata|TrEMBL
MTDHNFSIEFFPPKTAEGAEKLRATRARLSELHPKYFSVTFGAGGTTQQGTLDTVLEILA
AGEQAAPHLSCVGGTRESIRAILKQYQSHGIKRLVALRGDLPSGYGAAGEFRYASELVEF
IRAETGDWFHIEVAAYPEVHPQAKSPQADLDAFVRKVNAGADAAITQYFYNADAYFQFVE
QAHKAGVTVPIVAGIMPITNTTQLMRFSDMCGAEIPRWVRLKLSSFGDDTASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQVAPTTALWQRLVK
>A0A6I2FG22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces agglutinans|TrEMBL
MAATATDGGDCRLPISFELLPPRSDAAALALGRTIDRLADVQPAFISVTFGAGGSSRDRS
LTLLRYIREQTEVEPMAHLTCIGSSYAEANQLVREFLDAGITSFLALRGDPPAGTAGDDA
GTGDLSSAAELVQLIHRVQEEREPFGQFGIPGIPGASAIRTRPRPERVAVAAFPTGHPRS
RSAWQDVDALLAKEVAGANLAITQLFWHADDYLGYVERARAGGVTIPILPGIMPVTTTAR
LRRLTELTGVQPPAQLAIDLEIEPDAEAQAEIGVSFATELAREVLLGGDAPGLHLYTFNR
HEAVLGVIERLGLSEPAAPGFGTHRTTHERNTTKR
>A0A857DEG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter restrictus|TrEMBL
MKISEILKKGKPTLSFEFFPARTEKAAESLNKTIDDLVELKPDFVSVTFGAGGSTKDGSY
ELVKKLKKEKEQEVVAYLAAFALKKDEITAVLNNYKDLGIENILALRGDPPKDVDVTQVP
AESFKYASELAAFIRQNYSFCLGVAGYPEGHIDAPSIEKDIEYLKYKVDQGADFIIAQFF
YDNVYFLNFIERCQKNGIKIPVLPGIMPVYSIKMMEMLAGNCGAKIPLKLQKGISKLPEG
DTKALVDFGIEYAMGQCEELLKEGVRGLHFYTMDKSESAVGIVKGLRSKSFLTVK
>A0A857DI35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter restrictus|TrEMBL
MKISELFKTGKPTLSFEYFPARTEKNAEILEKTLGVLAGLNPSFVSVTFGAGGSTREGSY
ELVKKLKQEKKLEVVAYLAAYGLRPDEVAAVLDAYQDLGIENILALRGDLGKDGAKEIPA
DTIHYAYELVTFAKKNYNFCIGVAGYPEGHLEAPSLEKDIEYLRYKVDQGADFVIANFFH
DNIYFYHLMERCQKSGITIPVIPGLMPVYSVKMMEMLAANCGATIPEQLKRGIAALPEGD
ADALVEFGIQYAAAQCEELLQEGACGLHFYTMDRSESTAGIVKILREKGLL
>A0A849BPU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudokineococcus marinus|TrEMBL
MVTRGAPLRDVLADLRAEGRPSLSFEFFPPRDDAGEAVLWESLRRVEALDPTFVSVTYGA
GGSTRERTVRATREVSRETTMQPVAHLTCVSASRSELRRVVGEYADAGVSSVLALRGDPP
GGPGTAFERHPGGLRNALELVELVRSLGDFTVGVAAFPTPHPESADADQDARVLALKARA
GASFAVTQLFYEARLWTELVDRAAGHGCDIPVLPGLMAITSLRQVATFTKLAGAPVPARV
VERLEEAERRGGAAEVRRTGVALTAELGAELLDAGAPGLHLYTLNRSSASLEIVRALGLR
DPEHAGAPAAVAS
>A0A1M8KXZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus subsp. abscessus|TrEMBL
MTTNPLDRDGPVAELQDPGSIADRLTAVQPGEIAFSVEFMPPRDEAAEARLWRAARVFER
YRPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWVPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPTALEERLLRAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTARG
>A0A420EL57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alginatibacterium sediminis|TrEMBL
MGFHHAQQIESLNQSVSELKKINVSFEFFPPTTESMENTLWDSIERLQTLKPSFVSVTYG
ANSGTRDRTHNVIKSIQERTGLVAAPHLTCIDANEQELRQIAKDYWNSGVKNIVALRGDL
PSGSSKPNMYASDLVELLKQEADFDISVAAYPEVHSEAKSAQADLQALKRKMDAGANRAI
TQFFFDVESYLRFRDRCAAIGIESEIVPGILPVSNYNTLLKFANFANVKVPNWLHQQFQG
LDNDQNTRNLVGASIAMDMVKVLSREGVKDFHFYTLNRSELSYAICHTLGVRP
>A0A7L4W825|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus carnosus|TrEMBL
MKITDIYKTKNKKNKSVISLEIFPPKTDAGVETIYHTVAGLTNKPDFISVTYGAMGSFNQ
GNKTLRIAEKIKKDYNIETMHHLTSINNNPEQIAAILSDIKAKNVNNILALSGDMPVGAA
CSDFPDAYHFAYELINDIKKNGDFDIAAAIYPEGHVNSALEVENIEHVKRKYDAGANLFV
SQLFFDNEKFLRLNDYIKNSGIEAPIAAGIMPVLQKSQVERMIFFGASLPTRLIKIINKY
KDSPEDLQKAGMEYACKQIDDLLARGVDGVHIYTMNKPFVANTMMTKYL
>A0A5B2V265|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas brenneri|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGIASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLHNFVRKANAGANSAITQYFFNADSYFY
FVERVQALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCETLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A2W7S9M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseinatronobacter thiooxidans|TrEMBL
MSTPRVSFEFFPPKTLDASFRLWDTVRMLAPLSPSFVSVTYGAGGTTRQLTHEAVTTIGA
QFGLNVAAHLTCVDATRAETLAIADSYTKAGVTEIVALRGDPPKGQGRFTPNPEGFAHSV
ELIEALAATGNFKLRVGAYPEPHPEAADDLADVRWLKQKFAAGADSAITQFFFEADTFLR
FRDTCAREGITGRIIPGIIPIENWKGIRKFALATGATVPAWLDDAFEKATRDGREDLLAT
ALCTELCDKLVREGVEDLHFYTLNRPHLTRDVCHALGVQPQAGLEKVA
>A0A327VBW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PsTaAH-130|TrEMBL
MNPAATAPAAVGTALLDDFSLEMTGKDVPALEEAGGSIPRGTRINVTFLAGEDHATRLAA
ARAVRRLGFVPVPHISARRLPSRAALEEFLAGLAEDGTADDVFVVGGDPARPEGPYEDAL
AVIRSGLLERHGVRHIGISGYPEGHPAISGPALWSALTDKAAAIGAGPFTGDVITQFGFD
AEPVLDWLAAVRARGVDLPVRIGVPGPAGVRRLVGYATRFGVGTSASVARKYGFSLTNLL
GTAGPDRFLHALGERYDPARHGVVKVHFYTFGGLRTTAQWVGAFRERAR
>A0A0A8FM55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya zeae EC1|TrEMBL
MSFFHANHQEALNQNLAELQGRINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPLGGGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPIASA
>A0A0S8D2K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira bacterium SG8_35_1|TrEMBL
METHGSRLRSSLKDPDQFTLTFELVPGRGGRTQEINRIVNLAKDIAADGRFQALSITENA
GGQPALSPETLGTEILAMGSEVIIHLSCKDKNRNQMESLLFGWDRHNLHNLLVIAGDYPK
EGYCGYPKPVFDLDTLHVLDLLSSMNARGQIHSENDAAGAQEKSIPFLKGVVVSPFKMLE
SELVMQYYKLHRKVAAGADFVITQLGYDARKFHELLQYMKQNQLTIPVLGNVFIPSLKVV
ELMHEGKLPGCLIPDSLYEQIQWEARTADKGKKARLLRAAKLLAVLKGLGYDGAHIGGPV
LTFEDLDFVLTQADQMLSDWQNLIPDLSFCPPEAFHYYEKDQATGLNTPKETMRPPAKPP
WLSAYSFS
>A0A1Z8XM64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium TMED76|TrEMBL
MHIKDIINKGQPSFSFEFFPPKSDKSSDELLKTIKDLEPLDPSYVSITYGAGGTTRERTH
ELVEKILDLTNLVPIPHLTCVQHDDEEILRILNRYCDKGVSNILALRGDPPKGNNNYDRS
HDTFQYACDLVKFIRGFAKNTKSLGIGVAGFPEGHPETPNRLKEMDYLKAKIDSGADYIC
TQLFFDNHDFFDFRERCILAGIDVPIIAGIMPISSMQGLERMANLAGGSRFPAKLLKSLR
RCDSNPASIEKVGIQYATEQCSELLNNEVEGIHFYTLNKSEATKGIFESLGINKKSK
>A0A6P6IRN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puma concolor|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEASSGRFSVPPSISISHLTLPLWVLAACPLTLLPSTL
CSRNPAMVNEPRGDGGPMSRSEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRMES
GDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIAST
AVNYCGLETILHMTCCCQSREQITGYLRKAKRLGLKNILALRGDPVGDQWEEEEGGFSYA
ADLVRHIRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADT
FFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIR
NYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHP
KRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPRE
ELLKMWGEELTGEESVFEVFACYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVN
RQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELR
VNYHIVDVKGENITNAPELQPXAFTWGIFLGREIIQPTVVDPVSFMFWKDEAFALWIEQW
GKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLKRPGPEQETETL
>A0A2U8HB75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yangia pacifica|TrEMBL
MTRPDISFEFFPPRNIEATFRLWDTVQALSPLGPRFVSVTYGAGGTTRELTRDVVATLHK
NSGLKVAAHLTCVDATREETLAIARQFKEAGVNDIVALRGDPPKGASGFTPHPEGFNSSV
ELIEALREAGDFTIRVGAYPDKHPEAPSATADVEYLKRKFDAGASEALTQFFFEAESFFR
FRDACEKAGIDKPIVPGILPIENWKGARRFAEATGTKIPAWVIEAFEKAERDDRQDLLAT
AMCTELCNELLEGGVEKLHFYTLNRPELTRDVCHALGVVPDSKLENVA
>A0A8J4K1N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eudyptula minor|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6G9Y2H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia brasiliensis|TrEMBL
MRGGSTPGGPPRTPPNVSATPSVIQSLRTHSGTSVPFSVEFNPPRDAPAEARLWRAVRQF
ERMHPAFVSMTYGAGGSTRDRTVRVTGALAQETTLLPVAHLTAVEHSVAELRSLVGSYAD
SGIRNILVLRGDPPGDPLGAWQRHPEGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPD
LDSDTAYLAAKLRAGAEYSITQMFFDVEHYLRLRDRVLKVDPVEGAKPIIPELMPITSLR
TVARAEELCGRALPPAVLRRLHKAAGADPDGNPAAVREAGIEIATEMAQRLIDEGAPCLH
FITLNFAKATTEVLTNLGYGVTAAPISA
>C4V5G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas flueggei ATCC 43531|TrEMBL
MDMAQERVDIRGHIKKEPLIFDGGMGTYYAQKTHTRGKGVELANIETPIVVEGIHTEYLR
AGAQAIKTNTFAANRIVYQGEEALVQGILRTGWELAARAAESFGAYVFADIGPVAGLPPA
DIAEEYRFLSDTFLALGAKNFLFETNSSMEGLVETAAHIKQIVPDAFVLTSFAALSGGYT
RDGLFVEELIRTAAESGYIDAVGFNCVSGVQSMKELVHLIGTCPLPLSLMPNAGHPIVID
GRTFYESAPDYFGKGLAAIVREGVSIAGGCCGTTPEHIRALCKALEGGTAAEGERVRQER
TELTPSRSPFFEALKAGEIPIAVELDPPDTGNADKFMAGARELQAAGVHAITIADNPIAR
ARMDAAMLAGRVRRSLGIEPIPHMTCRDRNLNAIKSILLGLSAEGIHNMIAITGDPIPTA
ERDEVKSVYQFNSRKLSAFIKSLGERGDVIPFHVFGALNVNAKHFPSQLGLAKKKMEAGM
TGFFTQPVLSAQAKENLRTARDTLPGALILGGIMPVVSERNARFMESEITGIHVEERIIN
AYHGLDREAAEELAVELSLGIARDIKPYIDGYYIITPFSRTALVARIAAAMMKRQ
>A0A8J7D1R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Quinella sp. 3Q1|TrEMBL
MGRIAVEIIPRDEASLQADIDVIKKYPQVDCVNIPDLMSFDLRPWQAAKVTQRALPTIPH
VRAMDIDLKKPLTMRDEFIKFGIKEVLIIAGDPPKDLTRTVYPTETIDVIRKFREELPDV
KVYAGLDQYRGGIRDELYRVERKAQAGAVGFFTQPFFDLRFLEMYADLLDGHEVYWGVSP
VFSNRSRGYWERKDKAVFPKNFQPTMDWNIDFAKKVIDFIKTSSGGLYFMPITIDIADLL
PKVFD
>A0A1N6G2U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum sp. ES.010|TrEMBL
MSAPRVSFEFFPPKSLEASFRLWETVQALAPLKPQFVSVTYGAGGTTRKLTHEAVETIHN
HYGVNVAAHLTCVDATRAETMEIVDGYAKAGVTEIVALRGDPPKGQGEFTPHPDGFANSC
ELIEALAARAAFTIRVGAYPDPHPDSRGVGHDVQWLKRKFEAGADSAITQFFFEPETFFR
FRDDCDAAGIDGSRIIPGILPVEKWAGVRKFAETCGARIPAWVDDAYDKAVRDGREALLG
KALATELCTKLMEGGVQDFHFYTLNKPHLTREICHALGVQPQAHLEKVA
>A0A2M7WGD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division Zixibacteria bacterium CG_4_9_14_3_um_filter_46_8|TrEMBL
MLLKEAGTDIMNVADSPMARVRMSAVTAAYLIQNTTGVEVVLHLTCRDRNLMGLQSDLLG
CHALGIRNILAITGDPPSIGDYPSATAVYDVDSIGLTSIIKKLNSGFDYAGNSIGKPTRF
SIGIGINPNDNDSNREYDRLMRKIEAGAQYAFTQPLYELDPLLSFLDRIKIPDFPVFLGI
LPLQNFKHASFLHYEVPGINIPAPVLKRIQNARDQGIEEGAHIASELILQAANLVAGVYF
MPSFGRYAQIAGIIKEIKPKLIDIRKKGKN
>A0A1Y4KTT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoflavonifractor sp. An187|TrEMBL
MKIAELFGQGRPVFSCEIFPPKRDSPIDSIYRTLDGLKDIRPDFISVTYGAGGGGNVNHS
TQEIACMIENEYHITAMAHLTCVGCTKESALEVMNTLKAGGVENILALRGDHNPNAVSHT
DFLHADDLVSWIRQHGDFGISGACYPEGHPESPDVVSDIRYLKQKVDAGVTHLVSQLFFD
NDDFLRFWERCRLAGIEVPIEAGIMPVLSKASIQRMVSMCGASLPRKLTRILARYGDHPQ
AMREAGIAYAIDQISDLIAAGVDGIHLYTMNNPQVARQISDSITAIRSV
>A0A379BMS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia brasiliensis|TrEMBL
MLNPHKSFPARIAPAVRGVPSVVQSLRLHSRQRVPFSVEFNPPRDAAGEARLWRTVREFE
RMHPAFVSMTYGAGGSTKDRTARITGALAQETTLLPVAHLTAVGHSIAELRALVGSYADY
GIRNILVLRGDPPGDPLGDWHKHPEGVEYAEELVRIVRDLGDFNVGVASFPQLHHRSPDL
DTDTAFLAAKLRAGADYSITQMFFEVDHYLRLRDRLAAADPEQGAKPIIPELMPVTSLRT
VARAEELSGRALPAPIMARLLRAAGTGPEENRAAVREVGIELATELAQRLIDEGAPCLHF
ITLNFAKATTEVLTNLGYAVTAAPLSA
>R7XF91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp. GA3-3|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRDSIREILKKYREGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLENFVRKVKAGANSAITQYFYNADAYFRFVD
DVRATGLEVPIVPGIMPITNYTQLMRFSESCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A1V5VJU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium ADurb.Bin231|TrEMBL
MRVIDIYNKRKKPVFSLEFFPPRNGETLDKIFSTIDELKIFAPGFASVTGGALGSQRGGT
IAIVGSIKRKYNIEGVVHLTCVNKSKHDLENLLMEIKYNDIENVLALRGDPPRDSSASKD
YLPDYKYAYQLVKHINLMNNGEYLGESDGISFKGEPAGFCVSVAAYPENHPESASAEENI
THLKMKIDAGADYVITQMFFDIEKFLRFRDLAAKRGVTIPIVPGLMPVEKYKQVNFLLKQ
MGISIPSNFRQMLDSASDNPEKVKEICHNHDLNMARELIAAGVPGIHFFTMNRPEGTKRI
LERITDGSS
>A0A1S8BEE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diplodia seriata|TrEMBL
MEKITDKLAALPPDGRYFSLEFFPPKTQMGFANLQNRLERMANALRPLFVTVTWGAGGST
ASKSLELAELTQRQLGLTTCLHLTCTNMSRSLVDDALEQAKALGVRNILALRGDPPRSEE
YREGQAGTDNDSNKDFTWAVDLVRYIRDKYSDYFCIGVAAYPEGHSDQSHPDKQDPKFDL
PYLIEKTKAGADFIMTQLFFDIKAYEEFEAMLRNDPSGVFKTIPIIPGLMPIQSYQILRR
TTKLSHAKLPPAILERLDAVKGDDEAVKSVGVDILSEVVEELKARPNPGPRGFHFYTLNL
EKAVAHIVERCHLITATSPDNDDEEAVTIDDIPVNGETPSDSLKVKNRRRLSSANSTPHN
RVVVDRPSTSSNKSYEALADEAGVPKDKIMTRANTLAISEGEGTLGREATWDDFPNGRWG
DARSPAFGEIDGYGVSLHVSIPQAIKLWKYPTTVEDISDIFRRHIIGELEAIPWSEEGLN
AETETIRDQLLKLIAKGWWSVASQPAVNGIKSTDEVFGWGPKNGYVFQKPFVEFFLSSAD
WKKLQAKLDELSDVTYFAGNHAGDYSSNDEDSVNPVTWGSFAGKEIVTPTIIESVSFRAW
LEEAFSIWSEWRHIYPPQSATANLLGHIRDDYWLVNIIHHDFVEQDALWRLLFEE
>A0A087CD71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium psychraerophilum|TrEMBL
MRVWGTELHSTMFSLEVFPPKRNTPVGTIYDTLDGLQGVDPDFISVTYGTGKQSDRTVTA
RIAHTVKAEYGIPAVAHLTALYADQQTIDEELGLFEAAGVSAVLALGGNVLPDREPAHVF
DHASDLVTYIREHKPDMQVFAACYPECHPLAASLDEDIRHLKTKVDAGAERLISQLFFDN
ADFLNFIDKARAAGITVPVEAGIMPVTSAAQIRRMVSMCGSRIPEGLTRILDRWGG
>A0A7D6Y2J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter roggenkampii|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEL
>A0A2R7LS36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. HMWF025|TrEMBL
MTLPPLPRRVIGPVARAGERGQSQAGGRPRVSFEFFPPKTPAMEESLWQAITRLAPLDPA
FVSVTYGAGGSTRERTHRTVKRILDETTLKPAAHLTCVGASRAEVDEVIREYWETGVRHI
VSLRGDPPPTEGGIGGVYVPRADGYANATELTRAVRGIAPFEVLVGVYPEKHPESPSIEH
DIEVLKAKVDAGASLAISQFFFDMDAFLRFVDQVRAAGITIPILPGIMPVTNFNGLKKMS
AACGTAIPSWLGNLFEGLDHDAETRRLIACSVAAEMCAKLQEQGFEDFHFYTLNRADLVY
AICRVLGVRESIAAEEVAA
>A0A101W441|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gracilibacter sp. BRH_c7a|TrEMBL
MSVTWEVVPGRGAREKAQETALAAAESAVKGGKVHAVTITDNPGGNPAILADCLGVEMLK
MGIEPLVHFTCKDKNRNQMESQLYSLDRAGVRNLLVMTGDYPVAGYQGRPKPVFDLDPAH
VLELISEMNKGLEIQGPKGPSYQQKSDFYAGAAVSPFKGTEAELMIQYAKLKKKISSGAQ
FIVTQLGYDARKFHELLQFLKINNIDIPVVGNIYVLPFGAARLMNANQLPGCVVPDKLLS
DIDKERTAEDKGVGARLLRAAKMYGFMKGMGFAGVHIGGHGIKYEQVEYIIEKGEELSKN
WQDLVPEFDYPQPGGFYYFAKDQATGLNTDLPVNRKDLPLDAPVTLGYSLMRVAHALAFE
PGKPLFPLMQSIYKRRKNNKAHGLEHIIKVISNDCKDCGDCALLDLAYLCPMSQCPKNQR
NGACGGSYDGWCEVFPNEKKCVWVRAYARLKKYGEEDQLGNYCLPPANWNFYQTSSWYNF
FLGLDHSAQRLGIKSSKGEEK
>A0A7W1GY16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MGFIETLKARILILDGAMGTRLRELGYDGPLQDLANLHAPDLVRQTHREYREAGADILET
NTFSANSFRLRAAGSEADAREINLAGVRLAREAADGAFVFGAIGPCGKPLMPLGTIESAS
AYEAFVAQTRSLVDAGVDGFILETFADLDELEVAISAVRSVSNLPVIASKNFIEDGETLA
EGFPLRAAKRMAEAGADVVGANCVVGPQRMHDIIRWMAESGDVPISAMPTPGMPMLLKNE
LAYDTTPEYFGAAAARLIDAGANIVGGCCGTTPAHIAQLALAIKDRAPRVRALTRTAEAA
ARKPLEICEPSELSKKLGQKFIVTVELDLPRGLDTSKVLAGAASLKEKGVDTIDISDGAR
ARLRMTPLAICNIIQREVGIETMMHVACRDRNLLALQADLLAAHALGLRNVLAITGDPAN
IGDFPSATSVFDIDAVGLVRVLSRFNEGVDMAGNSVAKKCAFTIAIAFNPVARDIQAELT
RLCRKADAGAHIIYTQPLFERQHAEFACEQAMKLGLPIFIGVLPLRSQRHAEFMHHEVPG
IEIPDWLRKLMAESGDDAVEIGISVAQEFGKHLPTMSQGIYLMPPFGNHKVAEQVIEALS
L
>A0A7Y3HYQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIENANGTTQFTFEILPPLKGQNITSIYDSMDPLMEFKPPFIDVTYHREEYVYKE
LENGLLQKQVVRKRPGTVGICAAIQNKYNVDAIPHILCGGFTKEDTENFLIDLGFLGIDN
VMALRGDAVKSETYFIPDNEGHAYASDLVSQIADLNEGVYLDEEIQNQAKTDFCIGVAGY
PEKHMEAPSLDSDIYFLKKKIKKGATYIVTQMFFDNSKYFAFVDKCRSEGITVPIIPGLK
PIATKKQLNLIPHRFSCELPDDLVMQVVKCKDNQAVREVGIEWCVEQSKELVKAGVPVLH
YYSMGKSDNIKAIASTIF
>A0A7S1GDH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bicosoecida sp. CB-2014|TrEMBL
VPPAAPRAAMKIIDRIRENQRDGKTTISFEFFPAKTNKGVDNLLARIKQMSETLKPTFVT
LTWRSAFKDERLWLDIGRKVQVDMGVDILLHLTCHLPREAIRGILRRAREAGIQNILALR
GDPPIGEDRWRPVEGGLSNAKELVALIREEHGDYFCIAVAGYPEAHIECWNSPDLPPSVQ
SVALDRQRLKEKVDAGADF
>A0A7M3LYH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SAJ15|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGSSRDGTVRATERIATDTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVRYAAELVQLIKESGDFCVGVAAFPEMHPRSTDWETDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFAQLSNAAF
PPDLAERILAVQDDPAAVRSIGIDYATKLCARLMAEEVPGLHFITLNHSTATLEIYENLG
LHQRSG
>Q1ZWC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium angustum (strain S14 / CCUG 15956)|TrEMBL
MSDQYQPTPESELRVRYNDITRGVYFIGTTPPKTSTPIEDVEGIADRLVERIRDLAIDGL
IVYDIQDEASRTNKPRPFPFKSTHDPRHYSSLLNKKTDRPVITYKSVVQSETEAFDEWLN
EAWDEYRVRDMVLVGSPSAKNDVSLPLSKAYQTLAENRNDFFTGGIMIAERHAKKGNEHE
RLIEKYKQGCNFFISQAIYDTQATIDILTRYAIECKEQGLKPQRIILTFSPCGSAKTLEF
IEWLGVSVPEATSLRILNAENPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRKE
EIDGSILLYKLLRSSMDSHLAKHEFRLLKRKARANKLASA
>A0A370RFX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HB202|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKA
TQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A4Y8ZTG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas parva|TrEMBL
MSSLAPGIASWRKPLFEDVAGDIAVSFEFFPPKTEKMEQTLWESVKTLEPLAPRFVSVTY
GAGGSTRERTHNTVARIAQETSLAPAAHLTCVEASRGEIDEVARAYWDAGVRHIVALRGD
PPELGRPFAPHPQGYASAAALVEGLKRIAPFEISVAAYPEVHPEAVSKQSDLDNLKRKID
AGADRAITQFFFSPESYFRFRDEAAAAGIGAEIVPGILPVSNVAQTRKFAAACGAGIPPW
MDRLFEGLDNLPAARQLIAATVAAELCGQLYAGGVRNFHFYTLNRAELAYAICHLLGLRP
KADQQEQAA
>A0A0L0FQ72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaeroforma arctica JP610|TrEMBL
MRITDKLVQTAETALRKSIGFLAIDESTVEPATNCPYQFSIEVFPPKTVAGLQNLYPRLA
RLGSLGPLFIDVTYASGGETWEISLEICKVAQRAFSLDAMLHVACIGMTEDKCLEILNAA
KDAQIQNLLIIRGDEPVIHKRNNPKAQAEPLKVLNKALDMVQLTRKHFGDYFCIGVAGFP
EGRVGCGADKVDDGIAHLTEKVTAGADFILTQVFFDPEVFLTYMRKCREAGINVPIIPGL
MPITGYQQLVRVVKLAGITIPEGMAKTLDSIRNDDAKVQAYGQQVLQEIILKLKESGESN
FHFFTMNLEQPLTQILLDNQLSTVGENNKRRTPTSMRSLPFSQAQADGALGSRRESETVR
PIHWQYRPSTYKLRTSEWDRYPNGRWGDSSSPAYGSLSNYHLLTLHTSAGDKTVSKCGVT
IRSERDVFRIMSAFIEGKFPSLVLPWHDEPIAKETEQISSSLKELNDNGFMTINSQPRIN
AVPSSDPIFGWGPADGVVYQKAYLEFFCSAAKLEALFQILGKYPTMSLLAENEKGERRQH
KSQGRVQALTWGVFPESEIVQPTVTDQESFTAWREEAFGLWRVMWSDKLEAGTKARDVLE
SMISKYYLVSVVDHNYIDGDLFGIFNEIIDTAREEAPVRKPSINFFKSKKVR
>A0A412ZGP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEAQINDFNKGVFVDGSPIKITGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVEKVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKTIY
>A0A2E8DKU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIKQAKGSTQFSFEILPPLKGQNVQSIFDNIDPLMEFNPPFIDVTYHREEYVYKE
LENGLLKKQVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKSDVYFKPEKEGHAYASELVAQIEALNTGQYLDEELLNTSKTDFCIGVGGY
PEKHMEAPSLDRDIQFLKHKIENGATYIVTQMFFDNQKYFDFVDKCRKAGITVPIIPGLK
PIATKKQLNIIPHRFHVDLPESLILEIIKCKTNEQVKQVGIEWCIQQSQALKQANIPVLH
YYSMGKSDNIKTIASSVF
>A0A2E5FS52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MKSTQLRLLDEMTYELIPLKNVHEQGEFLPQSSTISITCSPAKDIEATLELCENFLDKGH
TTIPHFAARMVESEEHVTRIVKRVEALGIETVFIIGGDADQRGPFTDAPGLLRSFLDNNP
SIKTVGIGSYPDGHPSIPESALAESLIKKQEMILESNLNGYMATQMCFEANTILNWLKNC
RETGITLPCHLGLPGAVDMKKLINISLRLGVGVSSRYLKKNRKSVFKLLSPRGYNPNRLI
IPISNDAEELDITGIHCFTFNAVESTEAWRTKTMDRLT
>A0A3C0HNU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MALFKKNEVPEIVESDEARAHREHLTRNFTIEVIPMKSLDNARKHLPAGAPLSVTASPVK
GLEETQRLTEEFQAAGFEPVPHISARMVRDRAHCAELAHWLRDNGLKKMFLVGGDQDPPG
EYFDAVLFLQDFLEQDHGLEGLGVTSYPDHHAFISDEKLHEALHAKQTLLAEAGLPGWCS
TQMCFDAEVIEAWLRKERAEGLTLPVHLGVSGVVDKAKLMTMGVRIGLGASLGYLKKNRA
AITKMLTSTSYDPNDLMMPLSNAALELGIEGVHMYTFNQIEATEQWRAEALAELDG
>A0A357ZYV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTYIADLLAAGRTCSFEFFPPKTDDAARALEETIADLAPLDPSFVSVTYGAGGSTRERTR
DVVINIERNIGITAMAHLTCVGHTRAQLDSLLDEYKAAGVSNILALAGDPIVDDNGVVAE
SEFEYAMELVELIKEKSGFSIGVAAHPEGHPRSEDLYSDRRRLADKLNAADFAITQFFFE
AEPYLRLVEGLSAFGCDKPVLPGI
>A0A660SGS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-3 bacterium|TrEMBL
MFREKIESGRFVLTCEVLTPVEFDRDRLIEELRPLSDLVDGFNLPFCPLGRLRPHPIATA
LLIKDGLGSEPILHLAARHQTVLGFEATLLFCHSIGIRSILLVSGDPPREGEGNFRLNSI
HLLKIASSLNQGISISRRRIPPTEFLLSAAYNPNRPNIGGEHLRLHRKIEAGARVIFTQP
VFDPESFQERIRVIPDQIRVIAGLSFLYEPKIAWRLRKFLGIPHSYITRLSGDETGLLLK
TARKIRNSVDGFYIISIGRYDRALELIRRLKAEGIV
>A0A4Y9KYC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium frederickii|TrEMBL
MSGAMTDVTTPATADGHLKRPAISFEFFPPKTEEMERNLWDTINRLAPLDPKFVSVTYGA
GGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPV
GGIGTPYASHPNGYQSSADLVAGIKKRHGDIEISVSAYPEKHPEARDFDADIDTLKAKVD
AGATRAITQVFFDNDLYFRYRDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDW
FAAKFEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRA
KSVQKAA
>A0A5A8DPP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cafeteria roenbergensis|TrEMBL
MAGAPRKVSDMMADAVAAKTPFYSFEFFPPKTDVGRENLFLRIDRMSILEPIFVDVTWTT
AGDGKDSRDGTFSVCEYAKQYAGLTPMLHLTLTGLTRADLLRQLQRARDAGIRNILALRG
DPPKGATEWRPCENGLSRAEELVRLIREEHGDWFCVAAAAFPEGYKEPSVPRGGDRPRAG
DDGDAAAAAAGSADGAEGAEGAGGAVDAAARDVADRDAAVAAAAAKVAAGAEVLLTQCVY
DVEAYSGFVAACRAAGVPESVPIVPGVLPVHGYEAFRRMTAYTGVNVPAELQDALDAAAV
SGDDEAVRREGTARVSALCRALLEAGAPGLHFYTLNLEMATRAILKDVGLCRGAEARRLP
WRPLGDGPGALTQVRPIFWANRHRSYVERTRNWDEQPTGRWGDGQSPAFGALSESHFGGP
GAAQGTSEERRAIWGEAEALDGEGPVLEVFARYLEGQVPRLPWCDQALLPETAPIRERLV
RLNRSGFCTINSQPRVNGARSDDPHVGWGGAGGRVYQKAYVECFCSPARLAALMEAAPAH
PSITFTAVDASGNLYTNCKRRGVQAVTWGVFPGKEVLQPTVVDEAAFLAWKDEAFQLWAS
VWADAYPEDSPAAEVLHGIATSWYLVHVVDHDFVAGDVFRPFEAATAALRIASD
>A0A3F2V1D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ketobacter sp|TrEMBL
MNSQTQYDKRYSFEFFPPKTDAGVEKLKRVQQELAAKSPSFFSVTYGAGGSTRDRTFQTV
TQVKQNTGISTAPHLSCVGDSKSQLGEILQQYVSNGIERIVALRGDLPSGMGASIGELKY
ASDLVAFIREQTGDHFHLEVAAYPEMHPQAKSMNADLDAFRAKVEAGANSAITQYFFNID
AYKFFVDSCEKRGLDIPVVPGIMPIINYENLVRFSQMCGAEIPRWIRVRMESYSGDPTSV
LQFGEEVITSLCQSLLEMGAPGLHFYTMNQSAPTLAIWDNLDLS
>A0A2D6FPV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSIFRTKELPGDKAHRVALLKQARFEVIPLKNLAAQLPFLPAASEVSVTASPAKSLEDTW
SLSRELSKMGMKPIPHLAARMITGQDQLRMLIDQLPDIGASELFLVGGDAPEPFGPFNDS
IQVLEVILGMKHELTHIGVTAYPDGHSFIDSEVLSESLHKKEALLKGSGVEGHAATQMCF
DPRTIRTWLSEERKRGLSLPIHLGVPGAVERTKLLSIGARLGVGASLRFLKKNRATLARM
FAPGGYDPDKLLRPLNPELKSLGVEGLHVFTFNQVQSTVTWRDEAIAGS
>A0A7J4ZNZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzomonas japonica|TrEMBL
MTLLDKLTTEILTGDGAVGTMLYARGIGLDSNFEHLNLVRPALVLDLAREYAAAGAQVIE
TNTFGANYTKLAAIGLGHKVGEINRAGARIAREAAGGGGILVAGSVGPLVRMKGEERELT
PDAMEGHFRAQCTALAEGGVDLLLLETFGSLEQLVAAVRAARETGLPVCASMAFLEGGRS
GDGTTVEAFCAAVEAAGADMLGANCGAGPLELVKVVRRLAALTAKPISAYANSGFPEYHE
GRYIYRATPDYFAAMADELAATGANLIGGCCGTTPEHIAALARTLAGKRPAPRHPVASRA
AAGAQAGSRPDRASFLAPWGSRKVITVELDPPKGMDCRRIIESSRRLKEAGVDAINLAEN
PLARPRMGNIALGSTIQREVGVEVIIHITGRDRNLIGMQSDLMGASLLGLHTILAVTGDP
AAMGDHAGATSVFDLHSFTLIKLLSDMNHGVNAIGNPIGSGTGFTIGAAFNPNTKNMAVQ
AERLRKKVANGARFAQTQPVYDPALFLEALEQTRDCGIPLLPGIMPLVSERNAEYLHNEV
PGITVPDAIRARMKGLEKEAGAREGLAIAKEFIDATFTAAGGYYLIPPFGKCELALELID
YIHAREREQR
>A0A3B0SCV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MSVAFAHSKQEIDREVTKLARGFSIEILAKDANDVSQWKHRIPARTAVYIAQLPDQSFEQ
IVDAALKLQQAGVVAVPHLAVRKVSSKSWLRQQFTKLQQAGVQQILVIAGDRAVEQPVFS
SSFALMQTGWLEKFGFTKVGIAGHPEGLGFASKEKTTQILLQKCAYAKQSPAKFHIVTQF
GLEPQTTTRWEQDLRQAGVTLDIHAGMAGRINAARLLQFAVKCGVGSAVQLATKSPQKML
SISRRASAEKTIQALASYRLQQPDCLITKVHFFPFGSFAKTLHWASRL
>A0A132U0N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus riograndensis|TrEMBL
MKPDLRSAWKNNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYIGAGAVL
LESNTYSANYDKLSKFGLEAKVGDINRAGVQIARRAAGESGYVVGAVGSIRAGKRANLSG
TELKRFYTEQFSALLEEQPDGILLETFYDVEELHLALRSVRKLSDLPVICQLAVDETART
LDGLTLPEAFHILEQDGADVIGFNCRTGPNGIKRALKSLQGNLKLPASIYPNAGIADYVD
GQYRYGASPEYFGQMAPVFADMGARIIGGCCGTTPQHITEISTALRDYTPQPLPEPTGQR
DPERLIVQEHLAEDEERDGREPTLVDLVKERHTVIVELDPPRDLDIAKFMRGAEALRKAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIKQLNDGIAFSGKPLKQNANFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIARIAKATEHLEIPIFIGIMPLASGR
NAEYLHNEVPGIQLSPEVRSRMQGLEGEAGRAEGVRIAKELLDAATAHFNGIYLMTPFMF
YDMSVQLLEYVWAKQGRKLSPLFR
>A0A6G0S3P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora fragariae|TrEMBL
MKIIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMAEADIRKALDQTKDAGIQNILALRGDPVRGATS
FDECDRGFSHAVDLVRYMREHYGDHFCIGVAGYPEGHMESSDKKADVQYLKEKVDAGADF
VITQLFYDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTAFCNTFVPQEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRAAESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSSTSTPNERRAMWGEAPAAKEDIRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGVLSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
PSVQYHAVNLNGHSYSNASKSAIAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEDGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSPATSP
>A0A3R6UF28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. AF25-15LB|TrEMBL
MNIKEYIKEQRLITDGAMGTYYEEKYSEDTVIAEKENLKNPEQIKEIHLEYLRAGARLIR
TNTFAANTMFLADMQEVKETVRAGYEIAKEAVASFQAENGKEIPVFIGADLGPIYDLDHQ
DYDNVLQEYKEICDTFLSCGADCFVFETQSDFTYIEPVTAYIKEKSDAFILVQFAFDKSG
YTRSGLSMQRVAVEASEMENVDAYGFNCELDSTHMYQFMKNLKFSSDKFVSALPNAGYPY
TLRGKTIYSNNASYYAEKMKDIAALGTDILGGCCGTTPEYIALLSGELQDVPKAAKKIEN
VVTQEVTRTPSIFEEKLSRGEKAYIVELDPPFSEDASKVMKGAEDLRKCNVDLITLSDSP
MARARMDAGQLAVKIQQKTGVAVMPHISCRDRNVIALRAGLLGMHMNDVRHFLIVTGDPV
SRADRERVTSVFDFNSIKLMQYVKEMNLEVFAQEPVYYGGALNYHGANPDAIIERMKRKA
EAGCGYFLTQPVYTEEDVERLTYIKEHIDTKIMCGIMPLVSYKNAMFVKNEMPGIHVSDE
IVNRYREDMTREEAEEVAIELSVEIAAKLYDIADGFYFMTPFNRTGLIARIIEAIRQEEE
RR
>A0A837REF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus pentosus DSM 20314|TrEMBL
MRMNLKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHQSYIQAGADII
QTNTYAANRLKLTRYDLQDQVTTINQAAVKIAVTAREHADHPVYILGTIGGLAGDTDAAV
QRATQAEIAANVTEQLTALLATEQLDGILLETYYDLSELLAALKIVKAHTDLPVITNVSM
LAAGVLRNGTSFTDAIVQLHAAGADVIGTNCRLGPYYLAQSFENLAIPADVKLAVYPNSG
LPGTDQDGAIVYDGEPSYFEEYAERFRQLGLSIIGGCCGTTPLHTAATVRGLSSRSLVPH
NAPTHVAQAPTLVTTKSQHRFLHKVATEKTVLVELDPPRDFDTRKFFRGAERLKAAGVDG
ITLSDNSLATVRIANTAIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDIL
AVTGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNA
YRTDVSTKSISRKLSYGCDYIITQPVYDLANVDALADALAANQIDVPVFVGVMPLVSRRN
AEFLHHEVHGIRLPKSVLERMQQAELDGNERAVGITIAKELIDGICARFNGVHIVTPFNR
FKTVLELVNYVQQKNLTKVQ
>A0A8H6AVW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrytis fragariae|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRAIDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDGFEQKLRDHPSGAFKNIPIIPGMMPIQSYQMI
KRTTKLSHAKLPSTIITRLDAVRGDDEMVKKVGVDILSEMVEHLKSTKSQYSGPRGFHFY
TLNLEKAVSFILERTELIPNAETVAALEPEYVPTIPDIADLMSIHSGSHKRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGPKNGFVFQKAFVELFL
PTADWKTLHAKLTSPELRDTVSFYASNAKGDFISSDEAVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEESFGIWGEWARVYGKDSQTRKIIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLN
>A0A7W5H0U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacter margulisiae|TrEMBL
MRVIDLISNTKTTAFSFEILPPLKGNNIVRVYQTIDLLRPFDPKYINITTHRSELVYKEV
GDNLYKKMAERHRPGTVAIAAAIQNKYKINVVPHLICSGFTKSETEYALIDLQFLGIHDL
LVLRGDKAKHEKNFAQTNDGHAHAIDLQDQVNDFNAGKFLDGSSMEHTEAIFSYGVAGYP
EKHDEAPNMDSDIYWLKEKVKRGAEYVVTQMFFDNEKYFAFVDRCRAEGINVPIIPGLKP
ITFMNQLTALPKIFHVDMPEPLVLELNKCKTDAAATEVGVEWCTMQAKELKQHGVPSIHF
YTLMATQSVKRVAEQVY
>A0A849YEB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacillus sp. H12|TrEMBL
MKINELLKKRPTLSFEIFPPKNNENDITSIYATIDELAKMNPDFISVTYGANGSTSKNTC
KIASTIKNKYGIESVAHLTCMNNTKDEIKEILEELKENGIENVLSLRGDYPKDGDGINHG
DFKYASELNEFIEENFPNDFCLSGGCYPETHYEAKNFEEDLLNLKKKVDAGAKYLVTQIF
YDNQYYYRLVREARKIGIHVPILAGIMPAHNPKQLKNIAKMSNCSVPFDLAAMIDRFAGN
PKAGREVGLHYATYQIIDLMTHGVDGIHIYTMNKPEIAKEILKRTEYIRDEFFKD
>A0A3B0RCS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MSEKINSANIPPSLFAEPAKDMAVSFEFFPPKNDRMEETLWQSIDRLAPLNPDMVSVTYG
AGGSTRERTHATISRILKETDLVPAAHLTCVAATRGEIDDIAREYWDMGVRHIVALRGDM
PTIGAPYAPDPDGYVNAADLVAGLKKIGNFHLSVAAYPESHPDSMNVEADIDNLKRKIDA
GADQAITQYFFDVDMYLRFMDRVLAAGITVPVIPGIMPVTNFSQAKNFSARCGTSIPKWL
GKLFEGLDERPEIRRHVAATVAAEQCMRLYRGGVKQFHFYTLNRSELTATICHFLGLRPA
GDAS
>A0A225NUN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinibacterium profundimaris|TrEMBL
MTADGTGPGFAAGGRLERVLRSGRFAITAELNPPDSADPEDVYEAARPLGEIADAVNATD
ASGANCHMSSLGISALLVRAGYGPVLQVSCRDRNRIAIQGDVLGASALGVQNVLCLTGDD
VSAGDQPGARPVFDFDSISLLRTLKTMRDDGVFLSGRKITHPPKLFLGAAENPCVDPLDW
RAERLAKKVAAGADFIQTNLIFDLPRFERFMTRVRELGLHERCYILAGIGLLPSAKTARW
MRARVPGIHIPDAVIDRLEGASDPAEEGKLICIELIRAVRDITGVSGVHVMAYRREHQVS
EIVLRSGILDRRRITR
>E4PN48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter adhaerens (strain DSM 23420 / HP15)|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYREHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCEKLLAAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A2A5PFW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. YT-02|TrEMBL
MTKQVPISFEFFPSKTDVGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLSTISDFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQDIDRIVALRGDLPSGQVGLGELPYASDLVR
FIREHSGDHFHIEVAAYPEMHPQADHFDQDIKNFVTKVNAGANAAITQFFFNPDAYFYFV
ERIQKQGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIIKLCERLIAGGAPSLHFYTMNNTEPTRQLVTDLGLA
>A0A3B0WUX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKTQQKLDKQFSCEFFPPKTEKGMEKLLATAEMLKHEMNPAFFSVTFGAGGSTRESTFEA
VTKVQQCTGLEVAPHLSCISSSKPQLREILDSYKQQGIKRIVTLRGDRPNSDEVAQQSIE
GSFSYAVQLVSFIRENYNDDFHLEVAAYPEMHPEAANATRDFENFKTKISAGANSAITQY
FYNIDSYYYFIDSCEKAGIDIPIVPGIMPISSYPGLTRFSNVCGAEIPLWLRKKLESFGD
DTQAVKDFGAEFVSRMCEKLLEMGAPGLHFYTLNQTEASLRIWNNIKP
>A0A285JAW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudooceanicola antarcticus|TrEMBL
MTVPAVSFEFFPPKNLEASFRLWDTVQVLSPLMPRFVSVTYGAGGTTRELTRDAVGTLHK
NTGLNVAAHLTCVNATRDETMQIVEGFAKAGVTDIVALRGDPPKGEGQFTPTPGGFANSV
ELIEALSATGQFTLRVGAYPEKHPEAADSDADIAWLKRKIDAGAAEALTQFFFEPETFLR
FRDRCAKAGIEAPIVPGILPIENWPGLRRFAQACGTAIPAWLDDAFDKAIRDGRQDLLAT
ALCTEMCDTLLSEGVEKLHFYTLNKPELTRDVCHALGVTPRAKLEKVA
>A0A829PX88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus 21|TrEMBL
MTTNPLDRDGPVAELQDPGSIADRLTAVQPGEIAFSVEFMPPRDEAAEARLWRAARVFER
YRPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWVPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPTALEERLLRAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTARG
>W4QR25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus akibai (strain ATCC 43226 / DSM 21942 / CIP 109018 / JCM 9157 / 1139)|TrEMBL
MGLLEKLATQVLIGDGAMGTLLYEQGVDQCFEEVNVTNPEIILSAHQRYIEAGADVIQTN
TYAANALKLEKYGLETQVSEINKKAVQIAKTAATDKVFVLGTVGGIRRFQLEEWSLEEIE
KAFSEQVDALLSEGVDGLLLETFYDLEEAKMAVRLVKTKTSIPIIINLSLGEVGVMNRGI
SITNAFDQLTALGANVVGLNCRTGPFHMLRSFETIPLREDVYFSAYPNASLPDYRDGRVF
YQSNAEYFKAMGEKFIEQGIRLLGGCCGTTPEHIKAFAEVRQNVRPVTSKVIRPLIEFKE
ATQIRSKQTPLPEIVKKRKSVIVELDPPKKLSTKKFMDGAQALKNAGVDAVTMADNSLAS
PRVDNLALGAMIKQQIGVRPLVHITCRDRNLIGLQSHLMGLHALGIDDVLAITGDPTKIG
DFPGATSVYDVSSFQLISFIKQLNEGISFSGKELGQKANFSIGAAFNPNVRHVDKAVKRM
EKKIESGADYFMTQPIYSVEQIETLASETKHIDKPIYIGIMPLTGTRNAEFLHNEVPGIK
LTDEIRAAMAACGEDREASTREGIAIAKSLIDATLAHFNGIYLITPFLRYEITVELTKYI
ESKKLMIQGQR
>A0A8H9XDS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium sp|TrEMBL
MTFIPPNALGPVARAGAGVAQRPKVSFEFSPPKTPEAEANLWEAIRRLEPLNPEFVSVTY
GAGGSTRERTHRTVVRMLKETRLRPAAHLTCVEASREEVDEVVRDYWAAGIRHIVALRGD
PPGSLGGVYVPREDGYRNATELTAGIRQIAPFEVSVSLYPQQHPESPSIDHDIDVLKAKV
DAGATRAITQFFFDIDAFLRFMEKVRAAGVTIPISPGIMPVSNYKGLMKMAAPCGIPLPG
WLANLFDGLDKDPETRKLIAASVATEMCARLAEEGFSDFHFYTLNRADLVYAICRVLGVR
EDGPAPAAEAAA
>A0A8A4ZGD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pengzhenrongella sicca|TrEMBL
MPTTGFSGAPSPERAAPRPARANDRPTVSFELFPPRTPQTLEKLWTTVEALAAVRPDFIS
VTYGASGSTRQTTRDLVRELLASTSVLPIAHLTCVGTSRDEVTAIIEEFLDEGVRSFLAL
RGDPPAGQPDWRPNPAGLTRASELVDLIREVEAARCGLSPSQALRGAAHRLSVAVAAFPN
GNPIAGSSREQDLRALQAKQDAGADFAITQLFYDPQHYLDLVRDARAAGITIPIVAGLIP
TTEPARLLRVEALSGIRVPRELLAALEAADSPAQRHRVGIRASVEVAKAVLDGGAPGLHI
YTFNKHEAALDLLEGAHLRGGAPMAPPPAGRPQSTPAQPDYISI
>A0A8G1JYS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 3-2|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVTEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A7H8TNS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces chartreusis|TrEMBL
MTTTVRRRTTTTLREVLARDLAAGTPTFSFEFFAPKTESGTRGLWDAVRRIEPLSPTFVS
VTYGAGGSSKDRTVEVTRRLATHTTLRPVAHLTAVDHSVAELRHIIGQYADAGVRDVLVL
RGDPPGDPNGPWIPHPEGFTHAHELVALVKDISDFSVGVAAFPERHPRSPDWESDIRHFV
AKCRAGADYAITQMFFDAEDYLRLRDRVTAAGCTTPIIPEIMPATDVRQIRRFAQLSNAS
FPADLAQRLEAARDDPAEGHRIGVAHATQMAARLLTEGAPGLHYITLNRSPATYEIHRNL
GLTGRAVRAAA
>A0A7X6L2W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia gamkensis|TrEMBL
MTFDNVRGSSTPGRPSRTHPNVSGTPSVVQSLRAHAGHAVPFSVEFNPPRDAAAEARLWR
AVRQFECMHPAFVSMTYGAGGSTRDRTVRVTGELAQQTTLLPVAHLTAVEHSVAELRSLV
GAYADSGIRNILVLRGDPPGDPLGEWHKHPQGVSYAEELVRIVRDLGDFHVGVASFPQGH
HRSPDLATDTAFLAAKLRAGAEYSITQMFFDVEHYLRLRDRLAALDPIEGAKPIIPELMP
ITSLRTVQRAEELCGRPLPDSVMRRLRTAAGDGGEENAAAVRAAGIEIATEIAQRLIDEG
APCLHFITLNFAKATSEVLTNLGYGVTAAPVSV
>A0A7U8ZCP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli FVEC1412|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A525JDR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium sp|TrEMBL
MRRRSSDVGDQVLGPVARAGGGATPRPRVSFEFSPPKTAEAEETLWEAIRRLEPLDPTFV
SVTYGAGGSTRDRTHRTVLRMLAETKLKPAAHLTCVEASRGEVDEVIRDYWDAGIRHIVA
LRGDPPGQIGGAYSPRADGYANATELTAGIRAIGDFEVSVGLYPHVHPESPSIDHDIDVL
KAKVDAGATRAITQFFYDINGFLKFMDRVRAAGVTIPVSLGIMPVTSFKGLKKMSGPMGV
ELPAWLGNLFEGLDKDPETRRLIAASVATEMCARLAEEGFSDFHFFTLNRADLTYAICRV
LGVREPAEPTSTEAAA
>A0A1V5RSU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium ADurb.Bin315|TrEMBL
MRVTEIIQASKKPLFTFELVPPLKGRTLEPLMETIRTLMEFDPSYINVTNHQAEVVYIER
EDGLLQRKTVRKRPGTTALAALIQHTFDVPTVAHLICGGMSREQIEDVLIELHFLGIENI
LALRGDPPAGEKRFIPMPDGHAYSSQLVGQIVDLNHGRYLDDQYRDGEATRFSIGVAGYP
EKHAEALNMTVDLANLKKKVDAGAEYIVTQMFFDNGKYFSFVNACRSIGITVPIIPGLKP
IASKRDLSLIPQTFGVDLPEALTSELEGVDSNAEITEIGVQWCIAQSKELYAAGVPSIHY
YTLGKARNVARIVRAVY
>A0A327YIW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium aquaticum|TrEMBL
MKVTEHIQNANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LENGLLQKKVVKKRPGTVGICAGIQNKYEVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGHAYASELVTQISNLNKGIYLDEDLQNSTKTDFCIGVAGY
PEKHMEAPSLDSDIHFVKQKIKNGADYIITQMFFDNKKFFDFVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSVELPDDLIMAVVKAKDNDAVKQIGIEWCIQQSKELIAAGIPVLH
YYSMGKAENVKAIATEIF
>A0A2J9E4J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. FDAARGOS_194|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRAIAEDYWNNGIRHIVALRGD
LPANGGKPDMYACDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLTRFATMTNVRVPGWMNAMFE
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVLAA
>A0A374JV44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. OM07-7|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPE
AMKQAGIAYATDQIIDLLANGVNNIHIYSMNKPEIAIAIMNNLSEIIKC
>A0A0R0CJ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas terrae|TrEMBL
MTAISFEFYPPKTDDQRAQLDRTATKLKAHTPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLQAAPHLSCVGGTREEIRELLKLYRAIGVKRIVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLRHFKTKIDAGADAAITQYFYNADAYFHFVDA
ARKLGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWVSKRMQAFGDDAEAVREFGADVV
AGLCERLIAGGAPSLHFYTLNLAKPTNAVLERLSGS
>A0A318RG02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia limnetica|TrEMBL
MQRLAEPHPGPVPFSVEFYPPRDEQAEARLWRAVRIFERMGPAFVSMTYGAGGSTRDRTL
RIVGQLARETTLLPVAHLTAVGHSVDELRAMVGGFADQGITNILALRGDPPGDPLGEWIK
HPDGLEYAEQLVRLVQELGDFNVGVASFPEGHHRAPDLDHDTRYLVSKLRAGAQYSITQM
FFDVDDFLRLRDRVVAADPEQGAKPLIPGIMPITSLASVRRMVELSGSVLPANIDKRLAA
AAGGGPDEDREAVRAVGIDLATQMAQRLIAEGVPCLHFCSLNFAKATSEVLERLGMNVMA
A
>A0A133NCS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSIEKPDYISVTYGAGGNTKGRTV
EIADRIKRQNGLESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEKGD
FNYARELIEYIHKKKGDKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRHE
>A0A175M3F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum B2 433|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIKNILALRGDIPKDKDIIGE
YNYAFELIEKIKASNNFGISGACYPEGHIECKSLDQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQEKSINVPIQAGIMPVVNKKQIERIVKISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDIAV
>K6FG53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solidesulfovibrio magneticus str. Maddingley MBC34|TrEMBL
MRIRELMEARRPFVSLEFFPPKEREAWDGFFGVVEKLIPVRPLFVSVTYGAGGSTHAHTL
EIVSRLKTAYGLEPMAHLTCVGASKDKIRGFLDALAEAGVDNVLALRGDPPKGQETFVPD
SEDFQHASDLVAFIRAEYPNLCLGVAGYPECHPEAVSPEKDLEHLRHKLALGGSFAVTQL
FFDNDRYFDFVARARAAGIDAPIVPGVLPVLSLASIKRFAALCGASLPPAYMAALEAADA
AGGNAAVAEAGIAYAHAQAQDLLRRGAPGVHLYTLNKAEAVLSIVSGLEY
>A0A3M3PU85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. papulans|TrEMBL
MSRLGPLLTQKXXXXXXXXXXEQVRSYDEIGSMSQERRFSFEFFPTKTDAGHEKLLTVAR
QLATYNPDFFSCTYGAGGSTRDRTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLTQY
KDAGIKRIVALRGDLPSGMGMASGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARN
FEDDLKHFVNKANAGADSAITQYFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLA
RFSDACGAEIPRWIRKQLEAYGDDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAE
PSLAVWNNLQLPR
>A0A3R7P5G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. TMED20|TrEMBL
MKTALQRVLEAGKAAITAEVMPPRGADPVHTLAMATDLSGRVHAINVTDGSRAVMRMSSL
AVCRLLLDAGLEPVWQLACRDRNRIALQSDLLGAHALGIRNLLCLTGDPVKAGDQQTARP
VNEFESVKLLGQVDAFNRGEDPNGGSLADGATELFAGCAADPQSRSWSGLQRRLMRKREA
GARFVQTQMVMDPQALERFQKELAGPMEIPVLAGVFLLKSAKNARFINRVVPGACIPEEL
ISRLEGAPNPAEEGVAIASEQVRRYTGIVQGVHLMAIKAEERIPLILEMAGFSSLPG
>A0A6P0HFC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides zeae|TrEMBL
MGGGAHRLVDASGRGVRRDLGSVTVSDDLSGPPTPGDRQPSEPGRPSIGELLRRGDRSFS
FEFFPPKDAAGEEQLWTALHELQPYQPTFVSVTYGAGGSTRDRTIGMTGRIARETTLRAM
GHLTCVGHTRQELVEVLRAYAAAGVHDVLALRGDPAEGPSAPWTPTEGGLHHAVELVELA
RSLDGRLGTPGRFGIGVAAFPERHPGSESVEHDARVLAAKAAAGADFAVSQLFFRPSDYF
ALVERTRAAGADIPILPGIMPITNLASVRRMAELSGCEVPAEVMARFDGATEPAEVRRIG
VELATELCDALLAGGAPGLHFYTLNRSRATRDIFAALRIAA
>A0A3P3Q4I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoanaerobaculum orale|TrEMBL
MENIRDYLNNNVLLFDGAMGTYYDELTDDGIGCELANIKNPELIKGIHNEYIEAGAKAIL
TNTFSVGIDVFNGDRNLQKDVVVAGIDIANEAAKDRAYVFADIGPIHTGSNELAFEEYKV
LIDIFLEKGVKNFLFETRSSTSGMVLSAEYIKEKCSDAFITASFAVMPDGYSSEGYQYKA
LFTEITNSGVFDAVGLNCVSGANHMAKLLKDVDTKGLYLFAKPNAGYPVVRDDRVYYSSL
ANYFANQIEDILEMGVNIVGGCCGTTPKHIELLKKSMSGKLIKPRRAVKSEKNTAQNIRV
NRFKEKLDLGQKPIAVELDSPIDTNITKFIDNAKKIKAAGADIITIADNPIARARMDSCL
LACKVRNELDFDVLPHMTCRDRNVNASRGLLLGANAMGVDNVLVITGDPIPNAQRDEIRS
VFEFNSVKFANFINSLNNDVFESPMNICGALNVNSRNFSAELKKAVRKQENGVKVLFTQP
VLTKRAIENLKIARENLDIKIMGGIIPIVSERNARYMQSEVNGIYITDDIVEKYIGKERE
EAEEIALSMSKEIANEIYDLVDGYYLITVLNRVNLMERLIKTVKKVCDNR
>A0A6H0T9P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar andalousiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIKKETIQRPKVVH
THEKRSKAHATLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYNIALIEEVYEATKHLEQPTFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGILISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7C7UL70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MESQKQYPQQFSFEFFPPKTPEGAEKLRGVRDRLGALKPAYFSVTFGAGGSTQSGTHETV
LEIKRAGFEAAPHLSCIGSTRDNIHAILQRYRDAGIRRIVALRGDMPSGMQEAGEFHHAN
ELVAFIRETTGDHFHIEVAAYPEFHPQAPNAREDLLNFKRKVEAGANSAITQYFFNPDAY
FRFVDDIEALGLTLPVVPGIMPITNYTQLARFSDMCGAEIPRWIRKRLESFGDDRDAIRA
FGTDVVTALCHDLLEAGAPGLHFYTMNQSKPTLAIWKNLGL
>Q64DN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon GZfos17G11|TrEMBL
MGDEIYSDLMRELREGEYVFTGELEPEKAGDVNEPIEMARELVGMVVACNVTDNPQSFAY
VNSMAASYLIQKETGMECVYQLRCSDRNRMALLSDVLGAGALGLKNILALAGDHVSLGDT
PDAKPVFDLDSTTLIKLIRTMVDDGKDLGGNEIHNPPKLHVGGAAAPGAAHLKAEVGKVK
RKINAGVEYLQTQVVYYTDVLDKFFDELGKVDVPILVGIFPARTFGQADFFDKYVAGVDV
PPDYLEAMRATKAIKDKEKKKEEVDRVNIEFFTGFLEHLKGTPAAGCHMMAVGYPRIIPP
LKKLME
>A0A2M9YAK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira saintgironsiae|TrEMBL
MKKILEIYKTAKTPVYSFEFFPPKTPEGETKLFEAVEELSKVSPGYITVTYGAGGSTRDK
TIRITSELAKKFSLPAAAHFTCVGGNKDEIRVILNQIRESGIENLMALRGDPPKGEEAFK
KVEGGFGYASELISFIKEEGFDFCMGAACYPEKHPEASNLESDVDNLKRKVDSGASYLVS
QLFFKNSNFESFLNLIRQKGINVPVIPGIMPITSFTQIERFKAMAACEFPEKLVSDLEEV
KDQPEEFYKRSINFSVNQCRELVKMGAPGIHLYTLNQSPASLDIVRELKN
>A0A1V5XDV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin193|TrEMBL
MRTENLFKNKTVFSFEVFPPKRTAPIDTIYHTLDGIKGLSPDFISVTYGTGGYKNSADTI
EIATTIKNKYGIEAVAHLPCINLSKDEVLRLLTEFKRVGIENILVLRGDITPDNQLRTDF
RYASEAVAFIKENGDFNLIGACYPEGHNESGDIITDIQNLKTKVDSGVSHLITQMFFDNN
YFYSFIERATLAGINVPIQAGIMPVVNKKQIERMVTLCGVKLPKKFVKMMERFEHSPEAM
RDAGIAYAVDQIADLLSHGASGIHLYTMNNPYIAQRIKEAVSTLLV
>A0A4Z1CPX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides eburneiflavus|TrEMBL
MRERLDSGERSFSFEFFPPKDAAGEEQLWQAITELEPYGPTFVSVTYGAGGTTRDRTVAI
TARIARETSMLPVAHLTCVGHTTDELIAILRDLGEAGVRHVMALRGDPPGGPGSPWTPTD
GGLTYANELVALIRERTDLRIGVAAFPEGHVEATDLDHDARVLRAKYDAGAEFAVTDMVL
RASDYVGLVERAAAAGADLPIIPGIMPILNLRSMERMAELSRRQLPAEVVARLTPYADDP
QRLRAEGIAIATELCEALLDAGAPGLHFYTLNRSKATREIFGNLRITV
>A0A497XQ85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurisoma sediminicola|TrEMBL
MQNMKTELSCEFFPPQTAEGVDKLRAVRAKLAVLKPGFFSVTYGAGGSTRDRTLEVVLDI
QREGHAAAPHLSCIGSTRDSIRALLGEFKAAGIRRIVALRGDLPSGMADVGELRYANELV
EFIRKETGDHFHIEVAAYPEWHPQARSPREDLLNFKRKVDAGADSAITQYFYNADAYEHF
VGEARALGVTIPIIPGIMPIGSFSKLARFSDSCGAEIPRWMRRKFESYGDDADSIRAFGL
DVVTGLCQRLLERGAPGLHFYTLNQSVLTLEIARRLKLI
>A0A1G1KQ14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica bacterium RIFCSPLOWO2_01_FULL_45_24|TrEMBL
MTFCDKIKANKFIVTSEIGPPKGIDIKEALEDADLIKGKVDAINVTDLQSSVMRLGSLAV
CHLLKDRSIEPIFQIACRDRNRLALQSDLLSAAALGIENVLALTGDYTTLGDHPEAKPVF
DLGSIELLDVIKTLQEGKDMKGNALKGAPKFCVGAVVNPGADPLEPEIIKMEKKISSGAL
FFQTQAVYDIELFKRFLDAAKHLKTTILAGIVLLKSAGMAKYMNKNVAGVFVPDSLIKEM
EETKDKSAQSIEIAARLIKDLKPLCQGIHIMPIGWDRKVPLVLSAAEL
>A0A5E8VAG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. LVM 105|TrEMBL
MSGAMTDVTTPATADGHLKRPAISFEFFPPKTEEMERNLWDTINRLAPLDPKFVSVTYGA
GGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPV
GGIGTPYASHPDGYQSSADLVAGIKKRHGDIEISVSAYPEKHPEARDFDADIDTLKAKVD
AGATRAITQVFFDNDLYFRYRDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPDW
FAAKFEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRA
KSVQKAA
>A0A2P1PQL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ahniella affigens|TrEMBL
MASAISFEFFPPKTDEQRQQLDNTAARLKQLSPQYVSVTFGAGGSTLSYTPETVRRLRTE
FELDAAPHLSCMGGTRDEIKHLLKLYQAMGCKRIVALRGDMPSGMAGFGEFRYANELVQF
IRDQSGDAFHLEVACYPEAHPQAADMQSDLRNFCRKVDAGANGAISQYFFNADAYFRFVD
EARRAGVSIPITPGIMPIANFSQLKRFSDICGAEIPRWIERRMRGFGDDAESIREFGADV
VGKLCQDLLAGGAPGLHFYTLNRAKPTLAVLDRLGKA
>A0A249JY69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nanopelagicus limnes|TrEMBL
MSNDQRATSFSLEFFPPKDLAGEERLWQVLAQLQPLKPDFVSVTYGAGGSTRDRTIRVTT
EITDRTQIPTVAHLTCVGSTRSELVEVLNQYKKSGIKSILALRGDPQGGPTSEWQSIPTG
LDHADELVELAMQIGGFNIGVAAFPDGHPASDFNLEKDVDVLLRKEQLGATFATTQFFFE
FDKWQSIVDRLAKRGSNLPIIAGILPITNLKQLNRMVELSGVTIPAHISKRFENAGDDLS
EIKKIGIDIATELGSKLLAAKVPGIHFYTMNTAESTIVIAKNLGLVK
>A0A4R2XL87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella ornithinolytica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A0D6AV95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geminocystis sp. NIES-3709|TrEMBL
MISNFQTAIANKEFLITAEVTPPKGGNPQRMLEVAELLKNRVHAVNITDGSRAVLRMSSI
AGCYLLLQRGIEPICQVTGRDRNSIGIQGDLMGAYSLGIRNILALTGDPLKAGDHPQAKA
VFELESVRLLKLINKLNQGFDLNNKPLTDGNLNLFTGAAVDPQSKSWSGLQRRFDAKITA
GAKFFQSQLITDFDKLELFMNQIAVDCDRPILAGIFLLKSAKNALFLNKNVPGVQIPESI
IKRLEKAEKPLEEGIKIAAEQIQLAKNICQGVHLMAIKREDLIPRILDLANIDNLT
>A0A4Q7AS52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bouvetii|TrEMBL
MSLLSSYFQQNQFCILVEYLTSLNEIFPAKTQFAGYPAVMTLADRVHSDHDMAPLEASKR
YPLEVEKVLHFAGKGRDIQDFEIFLKQICATNIRNLLLLTGDKLKEHQNGENTAERSRYL
ESVNAVMAAKKAGGFCIGVAFNPFKYTEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAQAFLTQHHYAQKILACVMPLSLARAKFMLKHKVAGIVITQHMLNVLEEEQQAGLSER
VYLRCALQILICKQLGFAGIDLSACHKPEEQALLESYVEQYHDLDLNALEKLWKALWRVE
SGKEFQPALSCFSRPPSSSQLIKYHQLHFMHDALFDSNFAKGIGRFIFNSPFWERRPAAK
TLLKTEYISKHGIVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARIAKAVEQTQVLKEKLIPAVPIEVRGTSSWKNWYLATET
>A0A2D7VLT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacter sp|TrEMBL
MPPVTGDPGQPLVILEGHVSAGRLERVLRSGKFAVTAEIAPPDAADAEAVYERASVFDGC
VDAINATDGSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVTN
ILCLTGDGVQAGDQPDAKPVFDFDCISLLQTVTAMRDEGEFLSGRKLTTPPRVFLGAAAN
PFGPPLDYRPIRLEKKINAGAQFVQTQYCFDLVRLREYMSRVRDMGLTERCYILVGVGPM
PSARTASWIRDNVPGVHIPDAVIKRLLGAENQKEEGVRICVEMIQAVREIEGVHGVHIMA
YKQEERVRDIVEESGVLEGRIPWYPGVSNDQQGQQT
>A0A2U2DTT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium album|TrEMBL
MSPDINPFDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNGKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRAYMDKVRDLGFDEKCFILVGVG
PLASAKTAKWIRSNVPGIHIPDAVIKRLEGAEDQKKEGKQLCIDIINEVKEIKGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWTPEASPTDALVAARMNQMRQGTEQNQQQLAEIAAH
HPH
>A0A291DEX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia mucilaginosa|TrEMBL
MTTVHPALSFELFPPRSQASCESLLRTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQDGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSSAE
LHRIGVDYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEF
A
>A0A3A1WYH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium NR026|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNATGVFNHASDL
VSYIRSQRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>H6RX61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus saxobsidens (strain DD2)|TrEMBL
MKRALKVRDTATRASLRRTFEDLGYEVIPFKKTEEQVLQHVPTDVRLTVTASPAKGQDAT
LDLTVALAGHGYDVAPHLSAQQVRDRAHLADIVARCREAGISDVFVVGGDPTDTPTEFTD
AHALLVALHELDHGFTEIGIGGHPEGHPAVPEDVLFQALKDKAALATHIKTQIVFDPAVI
LTWARELTRRGIDLPVHVGVPGAVHRQKLLRVSGGLGIGESAKFLKKQQTLLWRFFVPGG
YSPDKILEGLAPHIGKPDNRIEGFHVFTFNDLGPTEEWRRGMLRNLA
>S5XW53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus aminophilus JCM 7686|TrEMBL
MTAKPGISFEFFPPRNLDQSFRLWETARVLAPLMPDFVSVTYGAGGTTRQLTHEAVTALT
SHCGLNVAAHLTCVDATRDETMKIVDDYAAVGVREIVALRGDAPQGQAKFTVHEDGFASS
VELIEAIAKRGGFTIRVGAYPEPHPESPDTAADVAWLKRKIDAGASSAMTQFFFEPETFF
RFRDACAAAGIDAPILPGILPIQGWAGAKRFAERCGTSVPAWADEAFSKAGKEGEARLAH
ELCVDLCEKLIAGGVDRLHFYTLNKPDLTLAVCEALGVHPQPGLSQVA
>A0A1Q3BGW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cephalotus follicularis|TrEMBL
MKVIEKIREAGDNKVMFSFEFFPPKTEDGVDNLFERMDRMVSHNPSFCDITWGAGGSTAD
LTLDIANKMQNMICVETMMHLTCTNMPLDKIDHALDTIKSNGIQNVLALRGDPPHGQDKF
VQIQGGFACALDLVRHIRSRFGAYFGITVAGYPEAHPDVIGPDGLASHEGYHSDLAYLKQ
KVDAGADLVVTQLFYDTDVFLKFVNDCRQIGISCPIVPGIMPINNYKGFLRMTGFCKTRI
PADVMAALDPIKDNEEAVRAYGIHLGTEMCKKILAHGITSLHLYTLNMEKSALAILMNLG
LIEETKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSRNPS
YGGLSDYQFMRRRALDKKLLEEWAVSLKGIEDIHEKFKKYCLGKLKSSPWSELDGLQPET
RIINEQLGKINLKGFLTINSQPAVNGERSDSLTVGWGGLGGYVYQKAYLEFFCSKEKLNA
LVDKCKALPSVTYMAVNKQGTWISNVGSTDVNAVTWGVFPAKEIIQPTVVDPASFVVWKD
EAFEIWSRGWANLYPEGDPSRKLLEEVQSSYYLVSLVDNDYIHGDVFAVFSDI
>A0A381WKS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKIIDILKQDKPAFSFEFFPPKDDVGFDQLFETIDNLKSWDPAFVSVTYGAGGSTRSKTI
DLVGRIKKEIGLESMAHLTCVGHSSDEILKVLESIKEQNVDNVLALRGDPPAGETNFTKP
DNGFGYAEELVQFIRERFSFCIGVAGYPEGHPESSNLKEDLSHLKKKVLAGASFIVTQLF
FDNKYYFDFVASLRKIGVDVPVIPGIMPIVNLKQIKRFTKMCGATVPPDLMVRLEKVQDD
PESVCQIGIDHATNQCEKLLMQGAPGIHFYTLNRSRATLSVLEGLV
>A0A8H6T8N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycena kentingensis|TrEMBL
MKLTEKIASLGPRAPFFTLEFFPPRTDQGFENLLARISRLSVLNPLAVSITWGAGGSTKE
RSLDLAGITQGDGLDTILHLTCTNMVQGMIDEALKAAKERGVKNILALRGDPPRGEEEWI
AIDPRFKHSADLIRYIRAQPEYASHFCIGVAAYPDGHTGQLNDERAEIEYLKLKVDAGAE
FIVTQLFYDVDGFFQWVKKVREAGITVPIIPGIMPIQTYASFLRLTKLTGARVPESVMQA
LEPIQNDDQLVKDYGVNLAIEMIKRLTKEGGIAGVHISTLNLEKSVLRVIEGLKWTGVQA
SPIMAQNKLIEENPQPNELTVTASTAASSAALGLANIPLPTDGEAGRGELNNASSWDDFP
NGRFGDFKSPAFGSTDLWGGPAIGPTDVLRHCGHPTSLADLTQIFLGYLHARIPITPFSP
TPLSPESLSILPHLERLTRAGWWTVGSQPAVDGARSDDPVVGWGPRAGYVFQKGFVEFFC
TEEEVRRIERRAREGGEGWVHWFAGNKSGKCRGNVPDDGRNAVTWGVFPGQEIVQTTIIE
RESFLTWKEEAFSIWSDWASLYRPGSAERKLLESVGDERWLVSIVHHDYRDPEALWTFVF
GDL
>A0A7W0K4C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MPGRASTVRELLVGGRRSYSFEFFPPRDDDGEAQLWQTIRELEALRPTFVSVTYGAGGSS
RDRTIRITESIASETTLTPVAHLTCVGHSRDELRSIIGRYADAGVRNLLALRGDPPTGAN
QTWTPTPGGLNSGVELVELIRELGDFCVGVAAFPAGHPEAPDLRTDTQVLVAKARAGADF
AITQLFFRSDDYRQLVERVRALRSDIPIIPGIMPITSLAQLERFARLSGTPVPEHIVARL
EALPSGDAVRGAGTELAIELCEELLDGGAPGLHFYTLNRSTATREIFASLQQRV
>A0A383AG40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
CERPVKSRTRAEPREFGQLLQDIVGVEAIVNRVVVHQPIEEEMRWVEETYKKFEIENLIV
VGGESSKIDYIGPSVNTALRAINGQINTNDGDIFCGSITIPSRIKESKNLINKSKNGSEF
FTTQVLYDSSKITRMISHYQARCREMKTFPRRLLLSFAPVSSQKNIEFLKWLGVEIPDKT
ELYLKEDPVSMIDRSLNVTVKVLNEILDYINESNSVVPIGLNVEHIMSYNFQASVEMLQE
LARIYREFCIKA
>A0A381YFN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
DAILITDNQSGRIHMSTLAAGALLIDAGVDPIVQLSCRNRNRISLLSDLLGCLALGITSI
SLVRGDRVPDDFQPRPKAIMDVNATELIRIANIMKKDENIAAPGSFFLGGVVTAHAPKPG
WPAKNITEKVDAGAQFVFTHTCLDLDILRTYMQRLGETKLLWNCHVVAGIVLLSSEEDAR
WVSKNRPNVIIPNDIITRLSKAKNPEKEGIEICAEQLQELSKIPSISGAHIIASEKLTNI
PVAIAKSGILETNKTS
>A0A382BAX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKSVLEAINKRGRKPFLLCDFSPPKGGNADLLLESYALNPDMFMVGYAPGKSVRLNPIFA
ADWIHSKTKIPSIFTVSTRDMNKSAMQSLLLGAELMGLPNVLIVKGDKFSAEDLNLQSEV
YDFTPTELISDVKAMNERRDFRGNELTYPTRFCIGAALDLSRDWEKESRLTKTKITRGCN
FIVSQPTFDPELPSKFLSFYEKTIGEKLKIPVMWGIQMVEKDTISFVNVPKWVHQDLEAG
GSSYEITIDLVKRYLEFGIDTFYLVPTIYKGGRRDYLSAQAVIEDIE
>A0A417YB56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanobacillus profundus|TrEMBL
MSLLSALEERILIGDGAMGTLLYSYGVDRCFEELNLTHEEQITRIHRSYIEAGSDLIQTN
TYGANYIKLARYGLEDQVKKINTKAVELARKAAKKDTFVLGTIGGIHGAQALNDTKEEIK
RSFREQLYCLLLEGVDGLILETYYNLDELLTVLEIAREETTIPIITNVSMHVPGILENGI
QLKDALQRLEDTGSNIVGVNCHLGPFHMLQSLKDVPLLDKTFLAAYPNASLPAYHEGKLV
YENKPDYFTRCAEDFRNEGVRLLGGCCGTTPEHIKGLAQGVRNLKPLTEKKIIRKPSPIE
VTRNQTTKETPLVDIVKKRHSIIVELDAPKHLQTDAYMEGVKALKKAGVDAITLADNSLA
SPRISNIAIAEKIKQEVGLRPLVHLTCRDRNLIGLQSHLMGLDTLGIHEILAITGDPTKI
GDFPGATSVFDVTSFDLIKLIKQFNKGLSFSGNSLRRKTSFKVGAAFNPNVAHLDKAVKR
MEKKISYGADYFLTQPIFNKEQIIQLHEATAHIQTPIYIGIMPLTSTRNAEFLHNEVPGI
KLNDDVRDKMRFVSNDRDKSIEQGISIAKELIDVSLRYFHGIYLITPFARYDMIIRLIEY
IQEKVPKSNFEEVLSATPHCL
>A0A383DQ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
GSTAKRTLEMSKTIQKYFGLEVMMHLTCTNMPVSSIKKVLLDAKKSGLSNILALRGDPPD
GAVEWKNNEKGFNYGIDLVRYIRKEFGDDFFLGVGGYPDSHQEQSDFDRDISYLKEKVDA
GSDIVVTQLFYDVNKFLVFRDKCSTIGINVPIIPGIMPIHNYARFKKFTQFCGVSVPGPI
VKTLESIKHDDASVIDYGIEQGTAMCEKLIAEGVPGLHFYTLNLEHSVSGILES
>A0A382IUF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MIRSISFEFFPPKTPKLEAKLWQSIEQLAPIGPKFVSVTYGAGGSTRTATH
>Q172A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aedes aegypti|TrEMBL
MTKEICPDDGHRREANSSSSSRTTSIIMHHLTVESDPPNSSTDYAKGRASPAEAMHSHEN
SRNLKQVIQQWTSSDRLSYSIELIPKEDFVLDLSRLSPKPMFCSLPWISDNNLQYQRFVD
TPMLKMTAKIVPHCSVMNHISCYNITETQVDKFVDMGNWNLFVVRGDTVSENQRFKHSSD
LVEYLLSKNNPDITIATGGYPYVHPESPSMDYDVKYLKQKVDLGVDFVLTQTLYDAASYL
QYVDECRRAGITVPIVPGIFLPSSYDQLETVLNLTRVNPPKGRAHHAPLARSSTNPAVFE
SVRGETLLSTWCGTLR
>A0A382P329|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MEILTRESDSFESNMTIETTDDLQDNLEQQTKWSMEILPHNFADVSLIPDFINEVYITMI
PGAACWETIQTAQQIKAVGKHAVPHIAARSFAGVEELSACLSGLQETGIERALLIGGGNS
QPAGDFSCVMDLLKTGLLAKYGINAFDFAGHPEGNPDDPNSEFHLLEKLRWTEERGIPAR
IVTQWCFDTDGTNAWISGLREKGIRNPIHLGIPGPSTIKTLMRFAKVCGVKASTNVLRKQ
GLSLSKLMFVNKPDKIISELSGYDQLHLYPFG
>A0A5U9GS67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella infantis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A382FP56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MRFIRDIHAEKEATGKPTISFEFFPFKTSEGEETFFGKTLPALMTARPDYASVTYGAGGS
TREKTLEIVERIQNDFDLTTMAHLTCVRHTQAEIGGILDEAAKRGIQNILALRGDPPPGE
EWAQAKGGFEYASELVSFLRERGGFGVGVAGFPEGHIDCPEGRDVDWRHLVGKINSGADL
IITQMFFDNADYFQLADFLGGQGVAAPLFPGIIPVASAAQIKKFSTMCGATLP
>A0A063Y0D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrincola lacisaponensis|TrEMBL
MKRSLSETLQDPQQGVYFIGTTPPRAGTDDEMMAEIAQKLLGRLNSIEYDGVVVYDIQDE
SSRIEQPRPFPFMETRDPREYAWLLSRLSGRETITYKSVAQRDRSSFEAWLKETHEQFSQ
QHLVLVGAPSSEGQVHLSLNEAYSALRESGLPFNLGGVTIAERHAVKGNEHLRLLQKSAQ
GCEFFISQAVYNPQATIDLLTGYARECRQRGETPKRVILTFTPCGSQKTLEFMHWLGISV
PAATRWRILDAEAPLSESIRICQNSLEQILEACLPLGLPLGLNIESLTNRKEEIDASIQL
FRLLKATLELQLAQRSLS
>A0A1Q6WAZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium 13_2_20CM_66_19|TrEMBL
MNAESGRTPIRVSFEFFPPADEAMGAMLWKSIERLAPLAPRFVSVTYGADGSTRERTHNV
VTRIQRETPLTGAPHLTCIGASREEILEIARGYWDEGIRHMVALRGDPPQGEGARRPNPR
GFRYASELVAALAGLAPFDISVAAYPEVHPEASSAAADLENLKRKIDAGATRAITQFFFD
TDAFLRFRDALATAGVHAPIVPGILPITRFPQVLRFAKACGTSIPGRLHERFAGLDDDHE
TRRMIAASVAIEQVEALRRHGVSEFHFYTLNRAELTYAICHALGLRPHARSASAALQEAR
A
>A0A1Q6WK05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium 13_2_20CM_66_19|TrEMBL
MIFEDEPVPGYPLPIRPGHTSPGRFERVLRAGQFAVTTELDPPDSADPEEVYRRARVFDG
YVDAINATDGSGANCHMSSLAVCALLTRVGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQALPVFDLDALTLLETARTLRDEHHFLSGRKITHAPRVLLGAAE
NPFADPIEWRAERLAKKVAAGAQFIQTQFCFDVPLLRTFMNRVEDLGLLDKVFILVGVGP
LRSAKSAEWIRTHVPGVHIPDEVVKRLAGASDGALEGRRLCIDLIQEIRTIPGVHGVHVM
AYRQEETVAEIIQRSGVLGGRVPWNPGRDPPANTNRMASGPTPSAALEPTRS
>A0A2N0MD81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium MP-SInd-SRR3963457-G1|TrEMBL
MKIKDILTKTRPISFEFFPPRSAEGIPAVLETMDELKAYCPDFVSVTYGAGGSTRAFTEE
ITLQIKNETGVEVMAHLTCVGQNKEEIDEVLQRLESEGVDNLIALRGDPPKGTTEFVPVE
GGFQHASDLLKYVKSNFKFGVAAACYPEGHTESVDLDTDLKYVKMKVDEGADFLVTQLFY
DNRYYFDFVERARAGGIDVPIIPGILPVLNSAQVRRFTALSGSEIPPDLDKLLDKYAESD
NSARDMGVEYATAQVRELWDSGVPGVHFYVLNRSYSVSRILDNLTISGHQRQD
>A0A417CJR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelatoclostridium sp. AM42-17|TrEMBL
MKINNLLNKRPTLSFEIFPPKNHGDDLSSIFLTISQLAKLNPDFISVTYGAGGSTSKNTA
KIASIIKNQYHIEAVAHLSCIDTSKEDLIDILNELKDNNIENILALRGDYPQDYDQRDLQ
GDFKYASDLNEFISEQFPDQFCLSGACYPETHFEAESFEQDLQNLKKKVDAGAKYLVTQL
FFDNQYYYRLIKRARQIGINVPIIAGIMPATSSKQLKRLSKISDCSIPYSLASMMERFLD
DPEACKEVGLHYATYQIIDLMSQGVDGIHIYTMNKPEIAEEILKRTKAIRREYFKD
>A0A542USQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. SLBN-39|TrEMBL
MTAVVGVEPLAGTTDAPPARPAPAGRARGGRFGALDRPTVSFELFPPRNPDAAPRLWSTV
RELEAAEPDFVSVTYGASGHTRATTRGLVRRLLHESSLTPIAHLTCVGTSREEVTAIVEE
FLDEGVRSFLALRGDPPAGQADWRPHPDGLQTAAELVELLREIEHRRCAGSPSQAVRARV
RPLSVAVAAFPRGNAATGGTRAQDVEALLRKQEAGADFAITQVFYEADAYLGLVAEAREA
GVTIPVVPGILPTTDPARLLRVQELTGVPVPRDLLALLDGTDDPAERHRRGIRASIDLVN
GVLDGGAPGVHVYTFNQHGAALDLLDGADLRGRGAEQP
>H4F1B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PDO1-076|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPQDVYERAKVF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VQNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDEAKFLSGRKLSTPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMAKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDSVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGILKGRQPWKRETGRSDAMVAERLHEIGSEPVQDQQALVDKAA
HLPH
>A0A0U1QZZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)|TrEMBL
MERKLSFEMNSAKNEKEMENIFKLIEFTDTLDPIYYTVNTEIGSSVWSDTYRTVIELREK
TDVPLIPHITINNKKEREIMQIIEKYINVGICEFFVIRGDKHVYDQDNPINYGVELIELI
RRSHKHIGIKTSLYPDFHKETTEVKEEIDWNERKYQLGVNEFISQLTLNTNALDFLSHWV
DKERPFTPSIMPLGNFSFIEKFTSSNSIDYPLWIKKFANSKSNSNEDKENIGIEIIRFLC
REYLNQRERLHVFTLNKVDVMKKIFQ
>A0A523UX50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium|TrEMBL
MKAGSNLERVLESGQFAVTAELGPPKGADAEVVKKKGSLLRDCADAINITDNQTAIARMS
SIACGTILTQLNLEPVIQVVCRDRNRLAIQSDILGAAALGIKNVLCLSGDHQKFGNHPQA
KNVYDIDAIHLIQVLKKMRDEKKLLEGDDLTIEPRLYIGAVENPYADPYEFRVIRLAKKI
RAGCDFVQTQGVFDVKKFKDWMRTITDQGLDRKVHILAGIIPIKSAGMVHYMRDYVSGVS
VPEGIVARMENAKDPRQEGINICLEIIDELKEIPGLHGIHIMAVAWETVVRIIVDKAGLA
PRPAV
>A0A0U1R2C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)|TrEMBL
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIAIDYWNSGIRHIVALRGD
LPPNSGKPEMYACDLVGLLKDVGDFDISVAAYPEIHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFD
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A3M2AZJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquificae bacterium|TrEMBL
MKIGQYLREKGFSLSFEFFPPKTPEGEQELFQTIKELEALKPTFVSVTYGAGGSTRDRTR
RVVERIHKETNITVMAHLTCIAHTKEEIYQIVQEYKSIGIENLLALRGDVPANMPDFRPP
DGACKHAEELVRFIRESFGDWFSIGVASYPEGHPESPNMEWELRFFKRKVLAGADFSITQ
MFFENQYYYSFLEMCQKWDINIPIIPGIMPITNLRQVQKFASMCGTEIPQALIDKLSAYE
DKPEDFIKVSVEHTAKQCLDLLDNHVPGLHFYTLNKSKATLMVYELIREKLPS
>Q9HJI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)|TrEMBL
MLNRRKEMLSSSIGSLNFVKSVEIVPSRNFGTDDLIAAADMLDGRVNALTCPENPRGSPG
IDPIMALYIISNERNIIPVPHITPRDKNRVHILSQIETAQKVGIRNFFTIGGDPINPKYE
SREVREIDVMEIIRMIKGRENAIVGAALNPYRDVEPEIVGAKIKSGADFFISQAVYSAEY
LQKDWIKKRNFKLIAGFLPLTKKSQVKFSENLGIVIPDSVKQRLLNSEDVISTSMKIITE
VFDEVKEYVDGIHIMPLGHNEIAAQILETI
>A0A377PXD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter pullorum|TrEMBL
MNKIENFIQILKSNEKCFTYEFSAPPSFSLDSFFDALQQENLVSKIHAFICTDSPLAKLK
HNAILASLKLQNAFNLPSITTISMRDRNTLAIQSELIGMNSLDLRLILALTGDPIRHGNQ
PQAKGVFEGNSLLLLKIIQQLNQAKDINNHPIQGDFKPFYAFSVLNSYSNKKENLYKKMQ
EKIQNGASAIITQPIYDLDIAQELLQWCDKINQESSTNCTLIFGFFPITSYKTALFLHNK
LPGVFIPQSWLETMEKASHNNTELEIGLEKSQRLFENLCKIQAKIHLMSSNKVDIIGKIL
NGR
>A0A482RW82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon|TrEMBL
MLAELKNFNPAFVDFTWGAGGSTSTLTFDLCKEAKETFGLNPNMHLTCTNMEISMIDTAL
DLCKQHGITNLVSLRGDPPVGQDRWTPKDSQLTCATDLVKYIRSKHGDYFCQSVGGYPEG
HPAAMITLPLEALETLSDREKTRYSIEDNAINICRDDAFASELAYLKTKIDAGARAIITQ
MFFDIEVFTAFVSSCRQAGILVPIIPGIMCISTYGGFMRMVKFCKTRVPEEVGQTGWVQ
>A0A835RG35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vanilla planifolia|TrEMBL
MKVIEKIRDAVDGEGRTVFSFEFFPPKTEEGVENLFDRMDRMVAHNPSFCDITWGAGGST
AELTLDIANRMQNMISVETMMHLTCTNMPVEKLDHALSTIKANGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIREKYGDYFGITVAGYPEAHPDAIQDEGGATLEAYNSDLAYL
KRKVDAGADVIITQLFYDTDIFLKFVNDCRQIGITCPVVPGIMPINNYKGFLRMTGFCKT
KIPPEITAALESIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMK
LGLIEESKVTRSLPWRPPANVFRAKEDVRPIFWANRPKSYISRTVGWDQYPHGRWGDSHN
PSYGALTDYQFMRPRSRDKKLQEEWAAPLKSLEDIHERFMNYCLGKLRSSPWSELDGLQP
ETKIIDEQLGQINLKGFLTINSQPAINGVKSSSPTVGWGGPGGYVYQKAYLEFFCSEEKL
TELVEKCNSLPSLTYIAVNKEGHSLSKVGSNAVNAVTWGVFPAKEIIQPTVVDPTSFMIW
KDEAFEIWTKGWACLFPEGDTSRALLEKVQRSYYLVSLVDNDYIHGDLFAVFKDL
>Q8Y6K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAILLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDDVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>I4HA75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa PCC 9807|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>A0A1G9B1J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium noncentrifugens|TrEMBL
MKVTQHIENANGNPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPSGLLEKKIVKKRPGTVGICAAIQNKYEVDAIPHILCGGFTKEDTENFLIDIDFLGIQN
VVALRGDAIKSEIYFRPEKEGHHYATELVSQISNLNKGIYLDEDLQNSSKTDFCIGIAGY
PEKHMEAPSMDSDIHFLKQKIKNGADYIITQMFFDNQKYFDFVAKCRKEGITVPIIPGLK
PIATKKQLNLVPHRFKVDLPDDLIMEVVKAKDNDAVKEIGIEWCINQSKELVKSRIPVLH
YYSMGKAENIKAIAQAIF
>A0A147HUM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sanguinis|TrEMBL
MTNTILTRAEAALAHEEPLFADVGGDIAVSFEFFPPKTEKMDAQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTLAAAAHLTCVEATREEIDQVAQEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPESTDKAADLDNLK
RKIDAGATRAITQFFFSPEAYFRFRDDAAAAGITAEILPGILPVSNVAQTRKFAALCGAS
IPDWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKGFHFYTLNRAELAYAISHLL
GVRGKKAEAVAAA
>A0A6P4WZ10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panthera pardus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEANSGRFSVPPSISRNPAMVNEPRGDGGPTSRSEGSS
SGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCCQSREQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDVCVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMWGEELTGEESVFEVFACYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A7Y5WXB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilia bacterium|TrEMBL
MSRLEDAIAAGRFVLTAELLTVNAGGLDAVHERFAPYEEYVDAVNATDNTAAHAHASPLA
VAIALQQLGMEPVMQLVCRDRNRLALEAELAGAALHGIENICCLTGDDVTAGDEPEARRV
FDLDSIQLIATANAMRNGRYLSGRKIDPAPRLFIGAVENPQAPPVGHRVDRARKKVRAGA
RFLQLQVLFELGPLERFMAEAVATGLAEQAAILPSICLVRTAKSLRYIDEHVPGISVPPA
VIERVERAADPEAECFEIGCELADAARRIPGVRGLHLISFRREAGIARLCGRLGIPTREE
RELGGDRPPVVV
>A0A7K9V015|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anseranas semipalmata|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVHGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A1I6R7U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. 453mf|TrEMBL
MADLREVLKNEVIIGDGAMGTELYKMGVPVGVSYEELNLISPDMVRDVHSRYIEAGARLI
ETNTFSANYVNLSKYGLEDQVEAINRAGVRVAREAMGDKGFVVGAVGAIRAGKRADISAA
KLNFNFEQQISVLVDEGIDGVLLETFYDVEELVIAIRQVRKLTELPIICQFAIDDIGRTF
DGFTMPEAFSILYKEGADVIGFNCRTGPSSIMRVMESVQNLGIPMSVFPNAGLAEYVDGV
YRYGASAEYFGQNAVRFADLNARIIGGCCGTTPEHIKAMVSALDNYVPAPLTVVDEELLP
IPVSVTEILADGSSAGTIRTEPTIVDLVKERHTVIVELDPPRDLDIQKFLRGAKTLKKAG
VDALTLADNSLAVTRMSNMALGYLAKEQIGLRPLIHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPSRFGDLPDSSSVYDLTSFEIIRMIKQLNSGIAFSGKPLKQKADFVVGAAFN
PNVKYLEKAVQRLEKKIAAGADYIMTQPIYDPKLIVQLKEATSHLDIPIFIGIMPLASGR
NAEYLHNEVPGIQLSDEVRERMAGLEGEEGRKVGTTIAKELLDVAMEHFNGIYIMTPFMF
YGMSEELTHYVWEKSGRAIKA
>A0A7Y3Q2Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 1-1(7)|TrEMBL
MGYTHASHIDALNQSISEVSDINVSFEFFPPSTPKMEETLWNSVHRLKNLNPKFVSVTYG
ANSGERDRTHSIIKAIKEQTGLIAAPHLTCIDASRDELITIADDYWHNGIQSIVALRGDI
PLGGGKPEMYAADLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNHVKVPQWMAKQFDG
LDDDPVTRQLVGASQAIDMIRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPR
>A0A836QJ43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MSSSDMSSSDSSRLSPWQKSTLRELMESGNSFLTAVELVNSRGVITERSGSGVILLARDL
AQHPHIHALSITDNPGGNAVLSADTLGTDLISRGQEVIIHLSCKDWNRNALQSHAWKLAS
EGFDNILALSGDCPAAGYGGRAAGVFDTDSVGLLKMLSEMNSGMETRMPSGRRSRLEKTR
F
>A0A7V9U3K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
RDRNLLGMLSDLLGASAIGLRNMLIITGDPPKMGPYPNATAVFDIDAIGLTNLVNNLNHG
MDPGGNAIGAPTCFTIGVGVNPGAIDLEHELRRFTWKVEAGAEYAITQPVFDVEQLEAFL
AKLDGNRIPIIAGVWPLVSLRNAEFLANEVPGVTVPEHVIARMRRANEKSKEHGVQEGIA
IAREMLERVRPSVQGVQVSAPFGKVELALEVFQDTLTPVPAAL
>A0A2E8H907|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
MWRRPPRPEGEQMALIRIGESLHCHIPSVQVSARRWLTGDTLDREAGQRHLRQLVDSQVA
AGADYLDVNVDDFLTDPLVGADGTRKLLAHVLDMIAEFGGVPPCIDSSDPGLLEFGLRHY
HEALGGPYTPLINSVTVNRLELLQLRAKLPFAVVGMLLERAGEGSDDQQAGFTDIADASV
YHNTARAIFTAAREAGCAADEVFFDPTVGPLGADMVGYTKRTFEGIRLIREDPDMAGAHV
VLGLSNCSDGLPRRLSINRAYLRVAMEYGVDAAICDAGQISGENLCDARILKLIRTIATG
EATDALTLLVEYAQSQPRSPAPPKRAAIPDPFGAALADPSKRVFVLELAPAEGSMDQIIQ
FAEQARDTDWIFTITDTPGGNRTPGPDTLALEVARLSERQPIMNLSCKSDDRNALIRRAL
ALYHQGLHHFFAISGDYPTGGRPVFDLDSVSLVMALDTLRRGIGFPDLLPRPGGALEEMR
IGAAVSPFKYKEADLIGQYMKAWKKKAAGADFFITQLGYDVAKFQEFKLWMGRAGMADTP
VIPMVYFLTPQFLRILNRVHVAGAVIPEDLKRKFQGRLGSKQDVKGGRRMSFGELADHQK
RMAVRRAALLSHILLDGLGYKGINLAGISSLDDARAVRDELDSLGGRDWHESWEEYRDAD
GQRPMDFSPVEDAFYLLPHGDDGLLLDEALLKADRSGYTPVDARMQKLHSRYFEPDKGLN
GLLRWMVGGDEEGFRLRAATLFEQAMKTSKLGCEMCGDCRISDLAYLCPEPTAGCAKRLL
NGPCAGADLNGGCEVHPERRCYWGRVIEAQLATGDLSALQPLQPPKDFSLAHTSSWRNEV
QGSCPEVFDVGRLPDTALPPK
>I0YN51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccomyxa subellipsoidea (strain C-169)|TrEMBL
MKIVDKMNESIKAGKTFFSFEFFPPRTDEGVENLYSRQHRMAAYGPTFCDITWGAGGTTA
DLTLDIAAKMQNTVGVETMMHLTCTNMPESQLENALDKVKSYGIQNILALRGDPPKGQET
FTVVEGGFSCALDLVKYIKAKYGDFFGITVAGYPEGHPDAIVSNPEEMDKAYWADLHYLK
EKIDAGGEIIVTQLFYDVDRFFKFVQDVRSLGITCPIIPGIMPIMTYGGFKRMTSFCKTA
IPSEISEHLEKIKDNDEAVKAYGIELGTQMCRRLLEAGTPGLHMYTLNLENASVSILQNL
GLIEKSQVSATVQVQISNDSKVKKGTEKVEESLSNGAELAVA
>A0A3D2Z2U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MSQILDAMRAGTLLADGALGSYIFELTGRLSETNHVYEAFNADRPEIIRDAYLAYLNAGS
RCLTTNTFGANDACLAGYGMAGRSGELSSAGVSVARETIDEFARTNGCGVDDYFVLGSVG
PTPAGDESPESLTDIYAAQLRALVEGGVDALLLETFRSVELLRGVLAEVARLDPGLPIIA
QMALNRDGGAWNVAPEELITVAAAGGAHVVGINCCAPWDAEAFVHSATATATIADGDLLL
SAMPNVGGFQHIGNRYMTRVNPEFMGQLARTMSQRGAQLVGGCCEIHPSHVWEMNNYLHS
RSGGGQATVAIAQQTEWPPTDGKVKRHNGAFSRKIVDREFAVSVEMLPSRGTAPKLLQAK
IDFVRELAASGLADALDITDGSRGIPLMPPGDFIQLVRQGLGWTDATGDALELIAHFTAR
DLNVMGVQARLIGYWANRIHNAVFITGDPPKMAPTYPPSTAVFDLDSVDMIGLAHMHLNA
GVDFGDQPLGKHRDPRTRFTIGTGFEPEALEGKRELDKLQRKIDAGADYVMTQPAFRWEP
LEAIRPFLEDVPVLVGVLILRGLDHALRMRDVPGVVVPDDVMQRLAASDDVQNQVRIGQE
IAAEQIRHIRADGWSGLYLMSPASHKPVVDVLRSGLS
>A0A1E3GG83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 51m|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAADLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVDKVNTGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>F5J375|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dysgonomonas gadei ATCC BAA-286|TrEMBL
MTVSELINKNDKTAFSFEILPPLKGNNIEKVYNIIDKLIEFDPQYINITTHHSEYLDQEM
PDGSVKRVNIRKRPGSVAIAASIQHKYNVAAVPHMICKGFSQEETEYALIDLNFLHVHNL
LLLRGDTKRLAPEQIYPNRNEYATDLQVQVNKFNEGIAADGTTFEKNATPFAYGMACYPE
IHEDAPNMESDIHYMKQKADNGAEYFVTQMFFDNEKYFSFVDKCRKAGITQPIIPGVKPI
VLMSQLEVLPRIFRSSIPEELAIELRKCKTDDESKEVGVEWGIKQCKELIAHGVPSLHFY
SLLATESVRRIAKEIY
>A0A3N5XHC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MRVIEHLDRAANPLFSYEIIPPARGKSVQDIIRVVEQVMPFGPPFIDVTSHPAEASYEEQ
RDGTVRRRIRKKRPGTISICGIISIRYKIDTVPHLLCRGFSREETEDAMIELNYLGIHNV
LAIRGDEPNYNKTVDPSKTVNVHAYDLVKQLADLKRGAYLEDIANSEPIDMCIGVGGYPE
KHVESPNLKTDIRHLKEKVDAGAEYVVTQMFFDNRHYFDFVKACRDAGITVPIIPGIRIL
DRLNQLTSLPKNFHNSIPEELSDAVQADPDHVKEIGKRWGIAQIRELLGAGVKCVHFYIM
SDAGPVLDVIRGV
>A0A2N2TQK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-17|TrEMBL
VSIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLPSLRAFGLDVVTDLCD
RLLAGGAPGLHFYTMNQAGPSTTIWQRLGLS
>A0A518CI72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polystyrenella longa|TrEMBL
MRLADIFRDHSQQRFSIEIFPPQTEKGEESLLNALTRLTEFGPGFVSCTYGAGGSTQQKT
LEWCEKIQNVLQQTATAHFTCVGSSREELVDWLNQAAGRGVQNIMALRGDPPRGETEFKA
AEGGLRYANELVELIREHSPNAGIGVAGYPEKHLEAPSMADDLDNLKRKVDAGADVIVTQ
MFYNNEHFFRFQEACQARQISIPVVPGIMPITNFQRIQRITAMCGSEIPEGLASRLEAVQ
DDEAAQFEIGVEFAIQQCRELLEAGVPGIHFYVLNKSQACEQILEELNFQTAT
>B9WCV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841)|TrEMBL
MSTVAERIASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFITVTWGAGGSTS
EKSLDLAATCQNEIGITTVLHLTCTNTNKEVIDQALSKAKAAGVRNILALRGDPPRTEEY
WTPNCDFSGAVDLVKYIRENYGDYFCIGVAAYPEGHVDGSDISSQNPQKDIPFLVEKVKA
GADFIITQLFFDVEKFIAFEKLLKEHDELKGIPLIPGLMPITTYKVFNRAAKLSHASIPR
GILKQVDQVCHDDNAVKALGVDILTEIIDRIDKSTNIRGYHFYTLNLEKAVASILDKSDV
LRQVLEGPSYAARFEDAVVSDSDDENEQENPPEGDVTLAKTNKPRRISSINDNELTSNKA
LVSKALLNDKKVLVDISTGKGALGKDAIWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHTP
EEASTKWGTPESLADLTRVFINYLSGKVDVIPWADSSLSPETALIQEELFQLNEKGWFSV
ASQPAINGCKSTDNIFGWGPRNGTIYQKSFIELFMPKEDWTKLLLKIELDKTVTYYVGDK
DGEIRSNLPIGPNAKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLWVEWARCY
KKNSKSFELLNSIYENYVLVSIIHHDFINENALWHLLLDE
>A0A7X7RQU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MKISDQTQKNRKRLSFEIFPPKKDIELENIDETLSVLCELNPDYISVTFGAGGSSNCNRT
IELAKKIKNDYHVEPVVHLTCLHYDKAEIDEFTRILELEGIQNILALRGDRNDNFPVKDD
FGHASDLITYLKQKHDFCILGACYPECHPESQSQVDEIKNLKSKVNAGAEVLLSQLFFDN
QKFFGFLEDCRIAKINVPIVPGIMPVINASQIKRMVTMCGASFPERFQKIIHRYEDNKEA
LFDAGMSYALS
>A0A2K9EC15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus tegillarcae|TrEMBL
MTVSTPKISFEFFPPKTLEASFALWETARALAPMEPDFVSVTYGAGGTTRQLTHEAVTTI
QKNYGLNVAAHLTCVDASREETLAIVQSYADAGVREIVALRGDAPKGQDGFSPHADGFAN
SIELIEAIAARGDMNIRVGAYPEPHPDSPSTDADVDWLKRKIDAGATSAITQFFFEADTF
FRFRDKCVAAGIDAPIIPGILPVQSWAGTKRFAKMCGTTVPQWADEAFTAAARDGEGREE
LLATAICTELCDDLIRGGVDRLHFYTLNRPGLTRDVCAALGVQPTRELRAVA
>A0A521YN55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MLLMRSWSVRHAGLLERVYRALEGVLRALRPLARAIGFERLQKPMAGLESAIKGFLFDCR
MCGRCALSLSGMSCPMNCPKGVRNGPCGGVRADGTCEALQGMPCVWVEGWKGSLCMSSGR
LPLAPSAPAEWNLAGRSTWVDVMAGEKAPARAAAEAPPQPSGSRLEALMQSGVFAVTAEF
SPPDSADAADVLARVAPFRGSVDALNVTDASGANCHMSSLSVAVLLTQAGCEAVMQVSCR
DRNRIAIQGDLLGAAALGVRNVLCLTGDHVTNGDQPGARHVGDLDSVSLLATARGMRDEA
RLLSGRKLKVAPQLFLGAADTPSAPPFEARIARLRRKIAAGAQFIQTQYCFDIGEFERYM
RAVREEGLHERLRILIGVGPVGSAKTARWLRAKVPGVHIPEAVVKRLEQAADPREEGRRI
CIELIRELREIPGIAGVHIMAPKQDHLIPSIVAESGVLAGRAPLFGAQGGRSVCAAA
>A0A2N5HQR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neobacillus cucumis|TrEMBL
MTFLDKLKNQILIGDGAMGTLLYSFGVDTCSEELNLSQSEQIQNIHRAYIDAGADVIQTH
TYAANYLKLQRYGLEDSVKEINSAAVRNAKKAAQSNAYVLGTIGGNRGIKTSSITIEEIK
RSFREQLYCLLMEGVDGLLFETFYDLEELETVLTIARKETKLPIITQVSLSEPGFLHDRT
PVNDALKRLEGLGADVVGLNCRLGPHHMLLALEQVEIPKHAFLSAYPNASLPTYTDGKFH
YEGDADYFQKSAQSFRNEGVRLLGGCCGTTPDHIRGFAAELKNSTPVTEKVVKLKKEKIV
VESPPKREYAPLQEIVKERPSVIVELDPPRKLDTTKFFEGAKALKEAGIDSITLADNSLA
TVRISNESLGYLLKSELGMRPLIHIACRDRNIIGLQSHLMGLHTLGMNDVLAITGDPARV
GDFPGASSVYDVSSFELIQMIKQMNEGLSFSGKDLGQKTAFSVAGAFNPNVRSVEKAVKR
LEKKIEYGADYFISQPVFSEEKLIEVYENTKHLNAPIYIGLMPLTGSKNAEFLHNEVPGI
KIADSIRERMSRLSDNPLEAAREGVAITKSLIDTALDLFNGIYLITPFLRYELTAELAAY
ANQRASEIRRASYAKNTIF
>A0A8I0DTT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. NSJ-10|TrEMBL
MKLKEYIQTKRIIADGAFGTYYISLYGDGSRAENGAGLSNLPELANIKAPERVIGIHTEY
IEAGAQFVRTNTFASNTKSLSADMEKVKENIRAAVMCAKMAAGKVDREIYLAGDIGPIPV
EGMLHSDRLTQEYIAIGETLLSQGIDILLFETFPELETILPAVTYLKENHDCTILVHFSV
NQFGYSNTGLSAKRLIAEANACPYIDGTGLNCGVGPGHMEKLIRKIVPDDTTFLSVFPNS
GYPKYLNNRLTFTDNAEYFTEKMEEIAALDVGIFGGCCGTTPEYIRRIAAGISADHPVRK
TETEAEKITVSEHPAYGFMERRVKEPAHKLIAVELVPPLNANDEKLLDAAHILKNAEVDV
VTFPDSPSGRTRADSVLMAEKIRLETGLCVMPHICCRDKNAIAIRSTILGSSLNHITNFL
LLTGDPVPVLFRQTTKSVFNFDSVGMMKIVQEMNSDTFTDHPVTYGGAINHNRMNTKAET
ERIRRKMAAGATFFMTQPIFSAEQADVIRQMKKETGATILVGLMPLVSRKNAVFMKNEMT
GIEIPDTIIERYREDMSREEGEACGVQIAREFMAVTDDFADGYYFSFPFNRVHMLKKILK
>A0A565CXF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabis nemorensis|TrEMBL
MTESSRGWSIWYGSIWNRLIIGGFMWIHISASENLVENRPNPPRSSCMIPVEVMAALEPI
KDNEKAVKAYGIHLGTEMCKKILAHGIKSLHLYTLNMEKSALAILMNLGMIDESKISRSL
PWRRRANVFRTKEDVRPIFWADRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQQLH
HL
>U5NBP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Symbiobacter mobilis CR|TrEMBL
MTSATVALSVEFFPPKTPDGADKLRTVRQQLYAMQPEYCSVTFGAGGSTQEGTFATVGAI
LSEGVSAASHLSCIGATRERVRAQLESLQALGVRRIVALRGDLPSGYGIGSEFAYASDLV
AFIREQTQEHFFLDVAAYPEMHPQARSPEADIQAFVTKVRAGANAAITQYFYNPDAYARF
VDDVRAKGVDIPIVPGIMPIVSSSQLLRFSDACGAEIPRWIRSRLQSYGDDLDSIRAFGL
DVVTGLCERLLVLGAPGLHFYTMNQSETTLDICRRLGVLSTKNLLQ
>A0A7V3HC42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MRFQILGTCPRELYQGQAAYNLLAIIQNKNTKVKIKDIIKNKKTFSLEFFPPKHETGLNE
LVATIKKLSVFKPDFVSVTDSGYGIAKGKNIALSQVLKETTGIEILAHMTCINNTSSEIR
NSIYELKKRGIENILALRGDKGNYRDFKSEFNYAVELINEVKKNGDFCIGVAGHPEKHPE
SLTFESDLLNLKHKIEAGGEFIITQLFFDNDVFFKYREKVLENHINAYIIPGIMPIHSLK
SFSEIIKKAGNLSIPPELKKMLNKEYSSKEDFIKYSVEYSTNQCIDLLKNGACGIHFFTF
NKSEIMQNILSEIKKYV
>M1RLS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenobaculum sp. HO|TrEMBL
MKIIELLKNKKGVSFEFFPPKSQKDKEALLETAKELKVFEPNFVSVTHGASGNSVSQKPP
IEYTKETVLELKNSLGLNIMAHLTCISHTKDELMSILGFYKENNIDNILALRGDIPKNGE
KRGCSHASELIDLIKTYFDDSFCIGVAAYPEGHPESPNMEWEIKYFKQKVEKGASFAITQ
MFFDNSYYYEFLDLCHKANIDIPIIPGIMPITNIKQISKFASMCGATIPSYITDALENLN
EEDVVKKGVEIAINQCEDLIKNGVKHIHFYTLNKSKATLQILKAIKL
>A0A3C1JBU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MKVTERLRTGEKVYSFEFYPPKTAEDTAKLFNTALELKALSPDFVSVTNSSSGVMPYRTV
ALCGVLKSQFGLEVVAHLTCLAHTRAEIAEICSGLRKMDILNVLALRGDPHNVADGALRR
DYSYASQLTADLVKDGGFDVGGACYPEKHPESPSPEADIARLKEKADAGAGYLITQLFFD
NDFYFRFLDRAAAAGINLPVLPGLMPLTGYRQMQNFTQMMKVTIPARLRAGIERWEGDKD
GMFKFSVEYASKQAEGLLKGGAPGLHLYTLNRSRAAMAIFKNLKGAARP
>A0A2E8P652|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivirga sp|TrEMBL
MSAFNDLVASRERPIVTAEFPSMDGGDLDTVAEAVDRFQPYVDAVNITDNPAAHAHASNV
SMAIAVKQLGLEPIMQVVCRDKNRLAIQADVVGAQMHGVTSFCALTGDDVTAGDEPEARR
VFDIDGPQLVSIMRTLSDGTYLSGRSLKHHRELLIGAVENPFAPPAHVRVRRARMKVDSG
ARFLQLQIXYEPEKLEAFVQGCVDNGVCRDAAVLPTVILTKSAGALRFMESSVPGIHVPG
DVIDRXASAVDPLEESYQLAREQAAQALSLPGIAGIHITDFRHDDSVHRLVHDLRLGPAF
STGATTTHAQTA
>A0A1M4ULA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides faecichinchillae|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSFGVACYP
EKHEEAPNIESDLYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKTAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEELVKETLKCKNDAEAEQVGIEWCVAQCKELMDHGVPSIHF
YSIGAVDSIKKVAKAIY
>A0A521XBR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MESQKKYPPAFSFEFFPPKTPEGMDKLRATWRQLLQLKPRFFSVTYGAGGSTRERTLEAV
LEIQKDGGEAAPHLSCVGSSRADLAATLALYRSHGLRHIVALRGDLPSGAASAGELRYAN
ELVEFIRASSGDHFHIEVAGYPEFHPQARSARDDLLAFKRKVDAGANAAITQYFFNADAY
FRFIDDCEALGIDLPIVPGIMPIANFSQLARFSDACGAEIPRWLRLRLQSYADDIASIRS
FGLDVVTDLCDRLLAQGAPGLHFYTMNQAGLVSTIWQRLGL
>A0A1K1NZQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas ruminantium|TrEMBL
MKRVSVELIPRDEETLRGELQLLKQYEGKIDVINIPDLLRFDTRSWEGSAIAQEYFAMSM
PHIRAMDIDLDKELPMKDYLREKGIKEVLVVQGDPPQRMTHEVYPTESTDVIRKFREEMP
EVKVYAGIDQYRSSMRHELYRTRRKVQAGAAGFFTQPFFDMRMLEIYMDMLDGLDVYWGV
SPVVTAASQSYWERKNNVIFPKHFAPTLEWSVDFSRQVMEMADKKDANVYLMPIKTNLEE
YLAGVLA
>A0A197JYF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Linnemannia elongata AG-77|TrEMBL
MKIVDKIAQKSAEGKPFYSFEYFPPKTTQGLSNLFDRIGRMQTLSPTFVTCTWGAGGSTF
DKTTELSAVAQTVHGLETCMHLTCTNMDRGKVDDALAEAKKAGIQNILALRGDPPRGQEY
WTQIDDTFVHAIDLVRYIRQQYGDYFCIGVAGYPEGHMDSTDITSDQEIGYLKEKIEAGA
DFVLTQLFYDVEGFLAWEKQCRALGITCPIIPGIMPIQSHNGFRRITNLAKIRVPAAVAA
ALEPIQSDDQKVKDYGVELAAKMIQQLLDAKITGFHICTLNLEKSVRLILERVGFVQPAI
QARKLQLNAPTHVNTDEGIPGPTDATAKDSYLNPLTWNPIDAQGLSESWDDFPNGRWGDA
RSPAFGDLDGYGASLKVEPRKALEMWKRPTGAEDISNLFVEFIQGKVPLLPWSEGSPLPE
TEAIQSRLVSCNERGLWTVGSQPAVNGKPSTDPLVGWGPKGGYVYQKAFVELFVGPNEVA
VMVQKLRTSSPWITFFAASRDGDVVTNVTGDVLEEQRKIAELKKVCNGTPSSSGSLKMTS
SEETPVCAAPFIKGGEDALVEGSNAVTWGVFPGKEIIQPTVIEKVSFLAWRDEAFEIWRE
WEHLYPKGSASQKLLHQIGHDYWLFNVVHNDFRDENGIWDIVLA
>A0A536W1Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTGNADRCFSFEFFPPATPQGVEKLIATREQLAQLRPQFFSVTYGAGGSTRDRTLETVLE
IQKSGQCAAPHISCIGSTRESIRETLATYREHGIGHLVALRGDLPSGSVDAGDFRYASEL
VEFIRSVSADAFHIDVACYPEYHPQARSPADDLASFKRKIDAGASSAITQYFFSASSYYY
FVDDAAALGIQVPIVPGVMPIASFSKLARFSDACGAEIPRWIRKKLESFGDDSASIRAFG
LDVVTDLCADLLAHGAPGLHFYTLNQASLTTIIWQRLGLS
>A0A1N6EDF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia phenazinium|TrEMBL
MNPLELSFEFFPPKTPDGVEKLRATRAQLAPLKPKFVSVTFGAGGSTQRGTLDTVVDMAK
EGLAAAPHLSCIGSSKESLRAILTEYRSHGIRHIVALRGDLPSGMGEVGEFRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQARSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESYGDDREAIRAFGLDV
VTDLCQRLIDARVPGLHFYTLNNAAATKAICDRLGA
>A0A1J5GT41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillatoriales cyanobacterium CG2_30_40_61|TrEMBL
MNRFRTACQTLDEFIVTAEVAPPKGADPSHMIEMVRLLKGRVHAVNLTDGSRAVLGMSSL
AASIILLHHGVEPIYQVACRDRNRIALQADLLGAGALGIRNILALTGDPVKAGDHPDAKA
VFDLESVRLLQAIDKLNQGKDWNNKTLPDGATDLFPGAAVDPQSSSWSGLKSRFERKIEA
GAQFFQSQLITDFDRLDQFMTEIADSSKKPILAGIFLLKSAKNARFINKYVPGVCIPDTI
IDRLEQSKHPLEEGILIASEQVKIARELCHGVHIMAVKREDLIPKILDLAGIKPLF
>A0A521YKD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MASNLQARLKSGDFVVTAEITPPVSTDPAEFVSRALPLKGLVTAINVTDGAGAKVHLSSL
AAAHFLLQSGIEPIFQMTCRDRNRLALQADILGAVSLGVHNMLMLAGDDPKAGDQPEAKP
VFDLDSKALLAMAHRMRSEQALPSGTEVKGGLDLFLGAADVPVDPPPAWDPRGLRAKAQA
GADFIQTQFCMDTGVVRRYAARLLELGIRLPVLIGVAPIPSARSARWMRDKLFGTLIPDA
IVERLERAQNPKREGRRICVEVLQELAEIPGVAGAHVMAPMNFAEIPAAIEESGVTRRKR
KT
>A0A7Y5Y9H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. C4D7|TrEMBL
MSPPSLIDAHPHLSENAPVALSYELFPPRSPAAAETLWTTIRELETTAPDYVSVTYGASG
SNRDTALDLINRLLVETTLRPLAHLTCVGNTPQELAGIIGDLLDIGVRGILALRGDLPRD
GGRPADGSLRYAQDLIDLIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEEHDVEVLL
AKQRSGADFAITQVFFEAAQYADLLTRARRAGVTIPIIPGVMPFTSLRRLNRLGELAGVE
PDVKLMERLAAADSDIDRLHVGVDATVDLANAALDAGAPGIHLYTFNEHQSALEVLDKLA
LPRHNRSSPARSAVARPQLAS
>A0A0Q1DQ43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. Sah69|TrEMBL
MGLLDELKQRILIADGAMGTLLYSHGVDRCFEELNLSNPDEIIHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGGAYVLGTIGGLRTLNKSVVPLDEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALSRLEALGADVVGLNCRLGPHYMIQSLEEVPLPNRAFLSAYPNASLPDYRDGRLV
YETNAEYFEEAAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTRRSVIVELDPPKQLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKEQLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPVYSEEKIVQIYETTKHLATPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACSGDPVEAAREGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A0B4WC08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum Prevot_594|TrEMBL
MHIKELFNQKNLVFSFEIFPPKVTSSIETIYETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTREDIDSIINELKENNIENILALRGDILKGKNIIGE
YNYAFELIRKIKENNNFGIAGACYPEGHIECESLEKDIKELKRKVDAGAEHLISQLFFDN
NTFYEFLNRTEQKNIKVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKEA
IRDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARRITESTKSIFNSINKDVAV
>A0A846FS11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanothece sp. SIO1E1|TrEMBL
MPASQSSNLGPQLCHPTARFRTAVQAGDFLITAEVMPPKGGDPSHMISMAHLLKDRVHAV
NITDGSRAVLRMSSLASAIILKSHGIEPICQMACRDRNRISLQADLMGAHALGIRNILAL
TGDPIKAGDHPEARGVFDLESVRLLQLIRKLNGGVDWHERSLSDGPTDLFAGAAVDPQLL
SWSGLQRRFERKIEAGAQFFQSQLISDFDRLEKFMGHIAIGANKPILAGIFLLKSAKNAQ
FINRNVPGVQIPPAIIDRLAQATDPLREGLIIAAEQVRLAEKICQGVHMMAVRREDLIPQ
ILDLAGIAPLKDISLNQAC
>A0A560LN13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium macuxiense|TrEMBL
MTETISSVPNGQRAPKAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTITRILRETDLLPAAHLTCVSASRGEIDEIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAGIKRRHADIEISVSAYPEKHPEAADFDTDIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A371WQP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylovirgula sp. 4M-Z18|TrEMBL
MSLHHPDDFGADPSAPLKDLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPEDVYERIK
VFEGWVDAVNATDGSGAHCHMSSVAISALLTRVGFSCVLQISCRDYNRIAIQGNVLGAAA
LGVANVLCLSGDGVQCGDHPEAKPVFDMDSTSLLSTVRMMREEKRFLSGRKITTPPRMFI
GAAENPFAPPYDFRPQRLAKKVAAGAQFIQTQYCFDVPILERFMARVRDMGLHEKVFILV
GVGPIASARTARWMRTNVAGVHIPDAMIARLEGAENQKEEGKKICIEQIQQIREIKGVSG
VHMMAYKQEETVAEIVHHSGVLKGRTPWRRDLVPTTQSVESLD
>A0A4V1KRR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leeuwenhoekiella polynyae|TrEMBL
MKITDHIKQASGKTLFSFELIPPRKGKSIQELYNNIDPLMEFKPPFIDVTTSREEFVYIE
KDGLLDKKVTRMRPGTIGICASIKHKYNVDTVPHVLCGGFTKEETEYMLVDCHYLGIHNL
MALRGDAMREEQYFKPTPGGHEYALGLVEQVVEMNKGHYLNGMVETSDCSDFCIGVAGYP
EKHLEAPSLKTDLKRLIQKVEAGADYVVTQMFFDNKKYFEFVDLVRAEGIDIPIIPGIKP
IAVKRHLQLLPQVFKIDLPQELIESVESCKSNTDVRQVGIEWAIQQSKELMEGGVPVLHY
YSMGKSDNVKAIASALF
>A0A2Z3I7S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium ESL0073|TrEMBL
MNRTDKLFSFEFFPTKTEAGLEKLLDNAKLMTQSCQPNFFSCTYGAGGSTRDRTLETVLQ
LTKKTQVSTAPHLSCVGDSKESLRNLLQHYKQEGVNRIVALRGDLPSGMGTASGELRYAS
DLVSFIREEMGDHFHIEVAAYPEVHPQALNMEQDLLHFVNKVNAGASGAITQYFFNADCY
FYFVERVQKMGITIPITPGIMPITNYSRLARFSDSCGAELPRWIRKQLEAYADDIESIQA
FGTEVITSLCEQLLAGGAPGLHFYTLNQAEPTLAVWKNLI
>C6BI03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia pickettii (strain 12D)|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRGILNTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGEAFHIEVAAYPEYHPQSRSARHDLENFARKVKAGADSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>M5PVA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocurvibacter africanus PCS|TrEMBL
MRISDLMRKRRPFVSLEFFPPKDQNAWPLFFEEAERLKAAKPLYASVTYGAGGSGQANTL
EIAKRLKNEVGIEPLVHLTCVGASKEKISEFLTELRKAGIENILALRGDPPKGSCDFVPD
NEEFQHASDLITFVRRHFPEFCIGAAGYPSPHPQSPSIEEELKWTKFKIDRGADFILTQL
FFDHRLYEDFVTRLRNMGVSVPIIPGVLPIMSLQSIRHILALCGANIPGNLYLDLEKAHE
QGGSEAVRRIGIQFATSLSKKLFELGAPGVHLYTLNKADACLEIVDGLKL
>A0A7C5QNG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MNEFLTTLRATPLLADGAMGSYLFEKTGRLSEANHVYEFFNLDRPELIQEIHLAYLAAGA
RCLKTNTFGANRHALQQFGLEKHTAAINRAGVRIAREAIARFQPAETVFVLASIGPGETG
GCREQIESLLAARPDALLLETFRSLDQLEAVLDLVQSFSDIPPIIAELTATSDPVGFIAR
MQQRGVPVAGVNCCAPWDADAFVNAVKDIPAVRDGAVLLSVMPNGGGFQRIGNRFMTSVN
PEYVGRLARSFLDRGVRLIGGCCEMHPPHIREMHNYLRSRQAVVSVTVPRVAARPPAGDA
EKRANGHFSRKLVDGQLVVSVEIVPPRGTDPNVVAAKLDVIRQLAASGLADAVDITDGSR
GIPLMPPGDFIHIARQSLGDALEFIPHFTARDLNLMGIQSRLIGYHASGIHNVLFITGDP
PKMSPTYPRSTAVFDLDSAAMVRLTHACLNAGVDFGGAPLGKQADPRTHFTIGTGFEPES
VNPGRELEKLRAKLDNGADYVMTQPAFRHEPLRVLEPFRGRGAFLIGVMVLAGLDHARRM
AEIPGVVLPDEILRRLAAFAQPSDQAKAAQEIAIEQVRWIRREGWDGLYLMSPAGAATTL
EVLQSGLS
>A0A6N1DTK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodospiraceae bacterium 2226|TrEMBL
MKSQRQHPRTYSFEFFPPKTEQGKEKLRATREALGALQPRYFSVTFGAGGSTQIGTRDAV
LEIQAAGFDAAPHISCIGSTRTGIAQMLNGYREAGIRRIVALRGDMPSGMGMGATGDFRY
ANELVAFIRETTGEHFHIEVAAYPEFHPQARSAQADLEHFKRKIDAGANAGLTQYFYSAE
AYFRFIESCEALGVDVPVVPGIMPITNFAQLARFSDACGAEIPRWLRKRLEGFGDDTASI
RAYGLDVVSELCQRLLDEGAPGLHFYTLNQAEPTLAIWQRLGLPAA
>A0A7C5K6L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
FNNILALTGDYPVTGYGGLARPVFDLDSVSLIAMLKAMNDGLEVQRPNGKMERLPKTDFY
IGAAVSPFKRYERELMPQYFKLARKIHCGAQWVIPQLGYDMRKFYEIKLFLQWAQLPANL
PVIGNVYLLNKTVAGLFNKNKIPGCVVSDALYALCEKYAAGPDKGKAFFVELAAKQLAVF
KGLGFAAGYLGGIHKADGFFQVIEKAESFGANDWKEFAKEIQFPKPGEFYLFEADPATGL
GDITRLNPEYKAALQKAPSVGYRLTRKVHEVAFTPGQGMFPTLQKVYEKLEQKGDNLALK
ALYAIERVSKEMAFGCKDCGDCSLPETAYLCPRKACSKTGRNGPCGGSADGRCELQDKDC
LWARAYDRLKYYGEAEHMLDGPAVFYNASLEGTSSWANLFRGRDHHAKKEK
>A0A2V6LJK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIIQGSSPTFSFEFFPPKTPEAADILYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEQEIEEILLRYAKAAIGNILALGGDRPVGIAYDKSR
DSFQHAIDLVRFIRRFNESGAHPDRRGFGVGIAGFPEGHPATPNRLLEMDYFKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALANIHIPIIAGIMPITSIGGLKRMAELAAGARFPAKLL
RALERCQSAPKMVRRVGIQHALEQCDDLLHNDVAGIHFYTLNRSDATRLIFDSLGIPRHR
SAQASSV
>A0A2V6BMX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHISDIIREDSPTFSFEFFPPRTPDAAEILYHTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIEAILLRYAKSSIGNILALGGDRPRGIEYDKSR
DSFQHAIDLVKVIRRFNEAGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVGAGA
DYIVTQLFFDNRDFYDFRERCALADIHIPIIAGIMPITSMSGFKRIAELAGGARFPARLL
RALQRCENDPEMVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRIIFDSLGIQRRR
SAQPQTV
>A0A0M8JIW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. C-1|TrEMBL
MTSNLNSLAEARRAAATPLFANLEGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLAPSFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASRAEIDEVARAYWDAGVRHIVA
LRGDVPGGEPYRAHPDGYANAIELVAGLKAVAPFDISVAAYPEVHPDASCAEADLDNLKR
KLDAGATRAITQFFFSPEAFLRFRDAAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMVSLFDGLDDHPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPISTAKDQAA
>A0A0G4K6E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira suanatina|TrEMBL
MSNNVENFIGKLENKDEYTFTLEISPQAKFDLGYIKDKIDDSKISDYIDAFVLTDSPFAN
LKISSILAALQLQQRLNNNKPFIATQTMRDKNSIALQNDLIGANYFDIRMVLAVTGDAIA
NGNQKQAKAVFEGNSELLISIIKDLNKGKSLGEFIFKEPLKPIYPFCVINSYAKNNDTLK
VRLAKKANSGVKAIFTQPIYESERLEILLKWIDELPLKEKPMLVPGFFPILTYKTAYFIY
YKLPGAYIPETWLNKLKKASDKSPEEEKKVAVELSSDLFHSMLKKHRKMHIMSMNNYDFV
VSLLKNIK
>A0A4R6UJ67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidicella xavieri|TrEMBL
MGLPLSFEFFPPKTAEGAQKLRHVRQQLYAKRPQFCSVTYGAGGSTQEGTFATVADILAE
GVAAASHFSCIGATRDRVREQLQQLQAMGVRRLVALRGDLPSGYGLGGEFQYASDLVAFI
RAEMGDAFHIEVAAYPEVHPQARSPQADLQAFATKVKAGADSAITQYFFNSDAYFRFVDD
AHKLGVDVPIVPGIMPITNASQLLRFSDACGAEVPRWIRLRLQSFGDDTASIQAFGLDVV
TDLCDQLRCAGVPGLHFYTMNQSGPTLALCERLGL
>A0A356J5A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MKIRNLIDDGKPEISFEIFPPKKDAPAAPVKEAVRRLAELKPSFISVTYGAGGGANVNTA
DVASFVQDCGVPSLAHLTCLSSTRARVEEEVAKLAARGVSNILCLRGDCPPGMTPADMPG
DFAHAVDLVRFLDGRGFCLGGACYPECHPECAHIADDLAHIKEKVDAGLDFLVSQMFFDN
NIFYAYLSKLLGRGIRVPVLAGIMPVTNAKQIARICQLSGSFLPARFKAIVDRFGDDPAS
MTEAGIAYATEQIIDLFANGVNGVHVYTMNKPDIAERIMGNLKCILGR
>A0A1T1GYY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4945|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGDHFKIEVAAYPEMHPQADSFDLDIKRFCDKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTDSIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A2V6M4X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRGNSPTFSFEFFPPKTPEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIQAILLRYAKSGIGNILALGGDRPAGIAYDKSR
DSFQHAVDLVKFIRRFNDSGAHSDRRGFGVGVAGFPEGHPATPNRLVEMDHLKAKVDAGG
DYMVTQLFFDNRDFYDFRERCALAGIHIPIIAGIMPVTSMSGFKRIAELAGGTRFPAKLL
RALQRCENDPEMVKRVGVHFALEQCHDLLDNHVAGIHFYTLNRSDATRLIFDSLGIPRRN
SAQAAAIFIE
>A0A653YJI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. 38|TrEMBL
MVSYAQGVDALNQSLSELRDIDVSFEFFPPKSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVKDTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIS
QFFFDTSVFLRFRDRAAAAGIDLDLVPGILPVTNYQTLVKFAGFTNVHVPGFLHKMFDGL
DDDDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRAG
>A0A2V5M7M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITEIMRGHSPTFSFEFFPPKTRHAAETLYQTIRDLESYMPDFVSVTYGAGGSTRELTH
DLVERIQHTTKLDPIPHLTCVCHKEEEIDAILLRYAKSVIGNILALGGDRPAGMAYDKSR
DSFQHAIDLVKFVRLFNESGVHRDRRGFGIGVAGFPEGHPATPNRLVEMDHFKAKVDAGA
DYIVTQLFFDNRDFFDFRERCGLAGVHIPIIAGIMPITSITGLKRMAELAGGARFPAKLL
RALQPCQNDPDMVRHVGIQYALEQCHDLLTNDVAGIHFYTLNQSGATRMIFDSLGIPRNR
NLQASNV
>A0A1B8YP29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus namnaonensis|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSINRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGD
LPENGEKPKMYGADLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFRQLKRFATMTNVRIPSWMTRMFE
GLDDDPESANLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A154BLZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerosporomusa subterranea|TrEMBL
MLKQKILNKAAGILTYGLTPPKSNNTPEKISEIAGKQIERIRDLPLDGLLIYDIQDEADR
IGDERPFPFLHTVDSAVYANDYLRELQMPKIIYRCVGKYSKPELAEWITGKSRQDKYSVF
VGASAKQQQVNIGLPEAYQMRSELNPNLLLGGVLIPERHSKYHDEHLRMIDKMDKGCQYF
ISQAVYNVETTKNVLSDYYYHCQNHHIDMVPILINLTPCGSIKTLEFMKWLGVNIPKWLE
NDLMNSQDILDQSIMLSKQIFEELLDFAVGKGIPIGCSVESVSTRKVEIEASIQMVQDIQ
GLFARHLVARI
>A0A5E4K464|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon|TrEMBL
MKIKDILSNKKFTLSFEVFPPKIEGDFEKLIKAVIELKRFNPDWVSVTYGAGGNTKNKSI
TIASVLKEFYNLEVLAHLTCTNSSKKDIKDVLYEMERKGIENILALRGDPPRGKKFEAIQ
DGFAYASELVSFIKKNNGFCMGGACYPQGHIESSSLENDMDNLKKKVDAGAEFLITQLFF
ENNKFYNFVDRAEKAGITIPINPGIMPITNYHQIKRMTELTGNEIPFKLKRELETRVSQP
EEIEKLGRHYAAMQAEDLKKNGARGIHFYCMNRSAIVAGILEMMGYQ
>A0A8J7YNY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sysuiplasma superficiale|TrEMBL
MLHTGRLERKLRQHYFVVTCELAPPQGATIEPLIKKAEAVRNHVDAANLTDCTSAMVRMS
SLAASVTVMKAGIEPVMQLTLRDRNRIGLQSDLLGASALGIRNVLCLYGDPPSAGNEKDA
KPVYDIGTDTLISGIRRMRDESLLMGGGKLTFPPSFFIGAAASPTEEESSKRIERIRKKV
DAGAQFFQTQPVFDLAVFESFMADMNSSGLSSAAPFIAGVMPLKSAKMARHIREEVHGIT
IPDDILERMERSTSPEETGIRIALETIEQVRKMRGVSGIHIMTVAWENVIPVIVERAGLT
PGDSLP
>A0A7M2XEC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. ES2-1|TrEMBL
MNASYDQPTYDKLREARTALDTPLFAGLPGDINVSFEFFPPKTDALMAQLWDVVETLGPL
QPKFVSVTYGAGGSTRDRTHGTVARIIREARLPAAAHLTCVDASKAEIREVAESYWEAGV
RHIVALRGDMGAPGVPFTPHSDGYANAAELVAGLKQIAPFEISVAAYPESHPDSPSSQAD
IDNLKRKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAA
ACGAAIPAWMDGLFEGLDTHPASRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYA
ICHLLGLRPKAPALEKAA
>A0A1G2XV98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium GWF2_41_51|TrEMBL
MTKTLTELLSRQIVFGDGAMGTMLYAKGVFINTCFEELNIANPRLVGQIHDLYIAAGSDF
IETNTYGANEIKLARFGYAEKTAQINEAAVKIAKQSADQSRDSQRSNPVDNGAGILVAGS
IGPLGINIAQGGFITEKDISNAFTNQIKAIASAGADFLLFETFHNLKELLIAINCAINNC
DLEIVAQMAINEQNETLYGDKIEYALAEISEFPQVAAVGLNCSIGPAAMLDALPIIKKAT
SKPISLQPNAGLPQNIDGRTVYMCTPEYMAEYAKRFYEKGVKIIGGCCGTTPDHIRQMTK
TVRPLHKADLSSAVIEIKPQPKQVVAQKPVALKDKSKFGAKLASGEKIYTVEISPPKGTD
VSNLIEKVKLCEKFGIDAVNIPDGPRASSRLSAMITAIKIKQSCNIETILHICCRDRNII
AMQSDLLGIQAVDIANVLIITGDPPKLGEYPDATAVFDLDSIALTKVVSNLNCGIDIAGN
ALPLRTSLVAGVGANPVASDLDREILRYKKKVEAGAEFAITQPVFDEKSLFKFLELTKNC
KIPVIAGIWPFTSYKNAEFMANEVPGVVVPPEILQRMSKTKDQQDGKKMGVEIAIELMEK
IKNAVAGFAISAPFGNVNMALAAAGKIGLEKI
>A0A5E4IB25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon|TrEMBL
MNYRSNLEKCLSERQFAITAEIGPPKGSDAKKIRDKAEFLRGSADAFNITDNQTAVVRMS
SFAGCVIILQMNMEPIMQLTCRDRNRIGLQSDGLGAAALGIRNIHCITGDHQSFGNHPAA
KGVFDIDSIQLLQIIKNMQDAGIFQSGDPLLAGRPSVYLGAAANPYADPFKAQVDRLWKK
IDAGAEFIQTQSVYNIEKFSRWMDDVRSQGLDRRVHILAGITPLKSVKMAERMKFHVPGT
DVPDSVYQRMIHASDPTKEGYTIALETIRELKTLSGIHGIHITALFWEEIIPDLVKNAGL
TARI
>A0A7K3CF53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4912|TrEMBL
MHPLDTASASVGTPLLEDFSLEMTGKDVPELEAADGTLPRGTRVNVTFLGNEDPRMRLDA
ARAVKRLGLLPVPHISARRLTSRTDFEQFLAGLRDDGTATHVFTVGGDPALPQGPYDSAL
ALIDSGLLQEHGVRHVGIAGYPEGHPALTDDTLRAALRDKAASLTAHGLTGHVTTQFGFD
PDPVLSWLEDVRDQGITLPVRIGVPGPAGVRRLLSYATRFGVGTSASIARKYGLSLTNLM
GTTGPDAFLRTLAERYDPARHGEVKIHFYTFGGLRATAEWIARFRQDNLV
>A0A0D5ZG47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon|TrEMBL
MPVSEIRTIEDIKFVKSVELVPRKEGGVEDILEAVDILGSSANFLTSPENPMGKPGIDPV
MSLYLASRNSNFIVMPHITPRDKNSLFVYSQVLTALKFGINHFFIIGGDPIDQTIGAKEV
REMDVMGMISAISGEDGYVKRQNGYGNSIRLGAALNPYREQEPEIAGKKLEAGSNFFISQ
ILYESQWLKKDWVKERKFKVVAGFFPLRKKSQLKFVKKMHVPVSEEVENRIENSDNVAET
SRKLILDTIDDLKGYIDGVHIMPIGHNEIARDILESV
>A0A3R7TN29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium TMED120|TrEMBL
MKIVDHIAQSKGKTQFTFEILPPVKGQHINSIFDGIDPLMEFNPPFIDVTYHREEYELKT
LKNGLLEKRLIRKRPGTVGICAAIMNKYNVDAVPHVLCGGFTKEDTENLLIDLDFLGIDN
IVALRGDAVKNETYFTATPGGHTFASELVAQISDLNKGIYLEEELVQASATDFCIGVSGY
PEKHMEAPSLDTDIQYLKEKIVAGADYIVTQMFFDNSKFFDFQEKCHAAGIDVPIIPGLK
PIATRRQLNLLPHRFHVDLPEALIQAVMTCKDNKAIKQVGIEWCIAQSKELQQAGVPFLH
YYSMGKSENIKAIADSIF
>A0A1T5A453|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalitalea saponilacus|TrEMBL
MPTAAQLIRDLKQPGFSFELLPPLKGNSIKRVYKTIDALKEFNPLFINITSHRDEVVFKS
IDNGLFEKKVTRKRPGTVAVAASIQHLYGIKVIPHIICSGFSKSETEYALIDLNFLGIHD
ILLLRGDKSKNEKFYQPQDEGNKYAIDLIHQVNDLNKGVFLDNTQAEAFDTPFSFGVAGY
PEKHEEAPNMESDLYWLKKKADAGAEYVFTQMFFDNSKYYDFVKRCREVGIDIPIIPGLK
PVTLMNQLTVLPKIFHTDIPEDFAKEIRKCKTDEQVVEAGIEWTTMQAKDLIANGVNLLH
FYTMMATESVRRVAKAIY
>A0A1M4XSL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium fontis|TrEMBL
MKVTQHIENAQGKPLFSFEILPPLKGQNIQSIFDGIDPLMEFQPPFIDVTYHREEYEFKE
LENGLLQKKIVKKRPGTVGICAAIQGKYDVDAIPHVLCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKTETYFKPEKDGNHYASDLVEQISNLNHGIYLDEDLKNTAKTNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNQKFFDFVDKCRKAGIEVPIIPGLK
PIATKKQLNLIPHRFSLELPDSLIMEVVRAKDNDAVKQIGIEWCIQQSKELLAAGVPVLH
YYSMGKADNIKAIAQEVF
>A0A444W3S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium anhuiense|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAIDLVKQINDLNCGKYLHEVMDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A1R1IJA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus sp. ZS01|TrEMBL
MPSTISRPTTVGELLSAAQGPLFSFEFYPPRSEEEEPILWRAVEALTPLEPDFVSVTYGA
TGSRRDRTIHATRRIATENGPLTVGHLTCVDQSKADIAEALAAYRDVGVTNILAIRGDMP
GGGEWVRHADGLANATELVRFIKEQGDFCVGVAAFANPHETTEDPELDDRILLAKVEAGA
EFAITQLFFDAQSYIDLVRRVRALGCSIPIIPGIMPLTVISQIERFAGLSGRALPDKFVA
ELRSAASKEEVREIGMATCLELCRTLLDAGAPGLQFFTQNRSKATREILAELKHLS
>A0A8J7JAE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenibacterium arenosum|TrEMBL
MTTPAVSFEFFPPQNLAGSFRLWDTVQTLAPLEPRFVSVTYGAGGTTRDLTREAVATLHE
TSGLNVAAHLTCVNATRAETLAIADGFAEAGVTDIVALRGDPPKDSGAFRAHPEGFANSV
ELIGALADTGRFTIRVGAYPDIHPEARDMAADIDWLKAKLDAGASEALTQFFFESETFFR
FRDACAAAGIDAPITPGILPIENWKGARNFARRCGAAIPTWVEDAFEKAVRDDRQDLLAT
ALCTELCSELIDGGVEMLHFYTLNRPELTRDVCHALGVTPKVQLQNVA
>A0A329ZBW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. 16-1353|TrEMBL
MNGDKNSLDIERLIEKILSDDEFLSYEIIPQKAFSLDSTLEKIKQSELYNLFDAFICTDS
PLARLKHSSILASIKAQNYLKKPTICTISVRDKNSIAIQGEILGLNEFDIRIFLALKGDP
IRLGDQPQAKGVFESNSYMLFDIINALNDGKDLANLNIKDNGRKIYPFAVVNSFANDMEN
IYKRMFRKVQKGAIALVTQPIYDINNAKELLLILERVNKELGKNAKLILGYHPVSSLKAA
EFLYNKLPGCYIPSKWIDKLRNASDERSLGLELSRNLYKELRAVYPKIHFMCANSIKMAE
SIILE
>A0A7G2C3F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Angomonas deanei|TrEMBL
MGKIVDAIRKANEESRQYFGFEFVAPTTESGLVTFYDRVERMSGLDPLFCGITWGDYGRT
ADTSIEVASTCQTLLSVNFQVNLTSYTATPEEIDKWLGLLQGKGVRNILATRGNTVGPAK
DGKVHFPHASDLIRYVRGKYGDYFDIAAVAFPESEEEGWNVEKEIEFLKEKVSAGADYVV
TSSVFDAGVFIDFCARCRRSGIKCPILPGILPIAHPRQLNSFHLANLTGVSELRKQLEGC
SAADCKQVVVSFMVDLVKALFAGGICGVYFFTMNVENIVSAIVKSLKMPTHRAYPWKPSE
NEERRRKEMVRPVHWSTRVMSYLARTSHWEEFQSSDKWITATVPTHSHPQSQQSTSDSSG
YHARLLLRSRAKRCTEFLKLVDMNDNILQGLEELCRIFLHFFDGKGTLPWADELSGETAI
IQEKLLKPLNARGLFTINSQPMANGVPSSDPALGWGPRDGYVYQKNYLEFFCSPSHAATI
FATLDKYPTIQYASIYRNGKMTKSRWHYEEDNSADADTPLGGGGENQSGGFTTTGIGSGL
FGSGVMALTWGVFPGREIIQPTIVSMDSFKAWSGEAFDMWAAPFPTNDVPNVIQMIMSEW
ILMVVVDNNFTSPISPMGLAMEELMAKIPPLVPINPAPSDLAGSTETEGVRGLSSQRPKF
VSPYL
>A0A6I3SVF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia buxea|TrEMBL
MTDHNFSIEFFPPKTAEGAEKLRVTRAKLSELHPKYFSVTFGAGGTTQQGTLDTVLEILA
AGEEAAPHLSCVGGTRDSIRAILQQYKSHGIKRLVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQAKSPQSDLDAFVRKVNAGADAAITQYFYNADAYFQFVE
HAHKAGVTVPIVAGIMPITNTTQLMRFSDMCGAEIPRWVRLKLSSFGDDTASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQAAATTALWQRLVK
>A0A7X3HG77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas otitidis|TrEMBL
GACYPEGHPEAENLRQDVENLCSKQAAGAEHLVTQLFFDNMHFYRFLNLARRAGITLPVS
AGVMPIVKRSQIERTVALSSASLPSEFTRMISRWQDDPAALYDAGIDYSIR
>A0A1I9YJ32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sprentiae WSM5005|TrEMBL
MNPIELSFEFFPPKTQEGIDKLRATRAELVSLKPKFVSVTFGAGGSTQQGTLDTVIDMAK
EGLEAAPHLSCIGSSKESLRAILGEYRAHGIRHIVALRGDLPSGMGAFGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQARSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARQLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCRRLVDAKVPGLHFYTLNAAASTRAICDRLGV
>A0A7Y7IFU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter wenxiniae|TrEMBL
MSPPSPHGAPPGASAPIALSYELFPPLNATASASLWGTIRELEATNPDYVSVTYGANGSN
RDTAVELLNRLLTESTLRPLAHLTCVGHTADELAGIISELLDHGVRGILALRGDLPQDPA
DGPRPGSLRYAQDLIELIRSVEQQRSALLCAGRVAIGVAAYPAKHPESPSIEHDVEVLLA
KQRSGADFAITQVFFHADQYRELVVRARRAGVTIPVIPGVMPLTSLRRVRRLGELTGVEP
APALLDALRRAADPADGRRIGVSATVDLARAALDAGAPGIHLYTFNEHGAALDVLDKLQL
PRPARPAPLRRTAIPELVQA
>A0A415UFY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobutyricum hallii|TrEMBL
MRMNIREYLENHKLLTDGAMGTYFDSIEKENYICSEEANITNPALVREIHRSYVKNGAQL
LRSNTFLANEGTFLSLTQAKAEAFENITLKQLIIAGYQLAKETAQEVYQEEYPIFAAADI
GPILEERDSEEADILQQYYEICDSFLEAGADIFVLETFPDTQYVLKMAEYIRKSCPEAFI
IGQFSLTPTGYSRTGFHYKTILQEATQSGLLDGAGLNCGVGAAHMKKFLKSYIEEFGVPE
DMVLTSLPNCGYPQIVRGHAVYSDSVPYFGEKLGEISELGVQVLGGCCGTTPEYIGEIYK
TVFQAKKTEGAVKIPTKIVWGDVTKRVQKRKEAAVHITQAGEQKEAIKEKQVTNTFRQKL
EIGELVCAVELDPPFDTDDTKLLNGAKALLSTKADIITIADSPLARSRADASLMAAKIKM
TIGMDVMPHLSCRDKNRIAIRSGLLGSYASGIRNYLFVTGDPVAREDREFTKSVFDFNSI
RLMKFAQSMNQEVFKDDTIFYGGALNQNGASPENIAGRMLKKMEAGCRYFLTQPVYDKEG
IERLTFLKERTGAKILIGIMPLVSRRNALFIKNEMPGIHVPDEVVAKYKEGASREEFEEA
AIEISKQIIEMGKGIGAGFYFMTPFNRVSLVKSILEYV
>A0A8C5A5T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gadus morhua|TrEMBL
MQINIIITDQFFGCPRLYTLSTMVNQVQRVDGSWQTSKSDSSGASNSGESSKESSRCSTP
LLDADRSDRLREKMRKRMESGDPWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITW
HPAGDPGSNKETSSMMIASTAVNYCGLESVLHLTCSNQSQETITGYLTKAKQLGLKNIMA
LRGDPLGTDWEDEEEGFNYATDLVKHIRSEFDDYFDICVAGYPTGHPEAQSYAEDLQHLK
EKVDAGADFIITQLFFRADTFLKFLRDCRAIGITVPILPGVFPIQGYQSLRQLVKLSKLE
VPEEIMEVIEPIKDNDAAIRSYGIHQAVEMCRVLLDSGAVPGLHFYTLNREVATTEVLRQ
LGLWIEDPRRPLPWATSANPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSP
AFGELNDYYLFYLKSKSSKDALLKMWGEELTSETSVFEVFTSYITAQVNRGGHKVMCLPW
NDDALATETNLLKDELEKVNRRGVLTINSQPNINGKPSSDPIAGWGPAGGYVFQKAYLEF
FTSSENVTALLKVLKKYEPRVNYHIVNVQGHNMTNAQDMQPNAVTWGIFPGREIVQPTVV
DPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQV
LDDMFELLDAVCTSRKTER
>D5BSS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceispirillum marinum (strain IMCC1322)|TrEMBL
MVDNKKPKISFEFFPPKSLSASFAIWETLHMLLPLHPEFVSVTYGANGSTRDLTRDMTKT
IAQTWHVDVAAHLTCVDATRHAVMNVAKGYLDVGVKQIVALRGDAPGGASRFTPTPDGFA
DAVELVAALAKRNFDKIWVGAYPEPHPDAAYDGADIDWLKRKIDAGATGAITQFFFDSDM
FLRFRDRAVKAGIDTPIVPGILPIENWEKTKLFAARCGASIPDSLAHEFDMAKRNNVEDI
LSVVVATDICVDLMDEGVDQFHFYTLNKPFITRDVCLALGIQPLKDNLIHANFRSDNITS
DARKSA
>A0A2D6M4D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTNVFHHAPTPPVAPPQRDGIKVSFEFFPPKTEKMEQTLWAAIKRLEPLAPQFVSVTYGA
AGSTRKRTHATVVRIRRETNLEPAAHLTCVGADRDEIDAIARRYWKEGICHIVALRGDQP
EQEDTYTPHPGGYAYASDLVAGLKKIADFEISVAAYPEIHPESQSVQDDLDNLKRKIDAG
ASRAITQYFFDVDVFFRFLDRAAAAGIEVPIVPGILPVTNFARVAEFCRACGTSVPPWMA
SMFEGLDNDSETRRLVAATIAAEQCQILQARGIKEFHFYTLNRADLAYAICHILGLRPQE
GVGGAAAETTAHGATGAADGGAE
>A0A2E9WWI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTNVSHHAPTPPVAPPQRDGMKVSFEFFPPKTEKMEQTLWSAIKRLEPLAPQFVSVTYGA
AGSTRKRTHATVVRIRRETNLEPAAHLTCVGADRDEIDAIARRYWKEGICHIVALRGDQP
EQEDTYTPHPGGYAYASDLVTGLKKIADFEISVAAYPETHPESQSVQDDLDNLKRKIDAG
ASRAITQYFFDVDVFFRFLDRAAAAGIEVPIVPGILPVTNFARVTEFCRACGTSVPPWMA
SMFEGLDNDPETRRLVAATIAAEQCQILQARGIREFHFYTLNRADLAYAICHILGLRPQE
GVGSGAAETTAHGATVAADGGAE
>A0A2D7DSB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaeta sp|TrEMBL
MHISDILAKGPTCSFEFFPPKTEKGAETLYETIQQLENLRPSFVSVTXGAGGSTRDLTHD
LVVRIKDSTSLDPIPHLTVVCHGEDEIRSILERYAQANVSNVLALAGDPPANKVDYNRKH
DAFQHAGDLVRFIRRFNEEGHHSSERGFGIGVAGFPEGHPTTPNRLVEMDHLKAKVDEGA
DYIATQLFFDNGAFLDFRERCALAGINVPIIAGIMPVTSIKGMHRMAELALGANLPAALQ
RAVARAGDDSEAVARVGTHWATEQCRALLDQDVAGIHFYTLNQSSATREIYRNLGLRDSE
GLQA
>A0A379B593|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Pasteurella] mairii|TrEMBL
MRVIAKDYWDSGIRRIVALRGDEPPGYDKKPFYASDLVELLRSVADFDISVAAYPEVHPE
AKSAQADLINLKRKIDAGANHVITQFFFDINSYLRFRDRCASIGIDAEIVPGILPVTNFK
QLLKMAALTNVKIPSWLAKMYDGLDQDQTTRNLVAASVAIDMVRVLSREGVNDFHFYTLN
RSELTYAICHILGVRPNL
>U2GRU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium pseudodiphtheriticum 090104|TrEMBL
MAPRVSASAPLDDSSDNPDNPDNAENTEPRTRSERTALSFEVIPPRHDADEKKISHLLET
LESYRPDYISVTSSCRSGWLDGTAKFISRIDRETNMRTLAHLACTAGTKQEMVAWINRLI
DSGVRGLLALRGDLPEGEVKLPEDHLQYADELVRLIREVEGQQAARFAAGRLAVAVASYP
NGHYQARTDDENFDVLLSKQRSGADLAISQLFFEAEDFLQFRRRAELAGIRIPQIPGIMP
ITSVRRLRRMAEFSSLPVPEHLVRRLENARDERAEGIAITAELVQAMVDNDVGSLHIYTH
NNAEVTQELLDAVGIRPPTAPG
>A0A148N828|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylothermaceae bacteria B42|TrEMBL
MIVRQTNLSFEFFPPRSPQIAQQLRETYRLLAKLKPGYFSVTYGAGGTTRENTFETVLEI
QRETGIDAAPHLSCIGSTRAEIQGLLQSYREQGIRRIVALRGDMPSGMHAMGDFRYANEL
VAFIRETSGNFFHIEVAAYPEVHPQATSYRADLLNFKRKVAAGANGAITQYFYNADSYFY
FVEDCRRHGIEVPIVPGIMPITNYSQLARFSDMCGAEIPRWMRKRLEGFGDDLPAIRAFG
IDVVTHLCEQLIEGGAPGLHFYTMNRAEPTLTICQNLGLAKA
>A0A496TH06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MKVIEHLKEAKETLISFEIIPPKRGGDIEDILDLVSRLKKYNPSFIDVTSHAAEIEYIET
DRTIKKIVMRKRPGTLVVGSEIQRSEKYGIDTVLHVLCRGFTREETEDFLIEMNYARLKN
VLAVRGDSERYKTNSIERSVNNYAVDLVKQIVDMNNGKYLNNPHSKKTDFCIGVCGYPEV
HFEAPNMETDIKHLKGKVDAGADYIVTQMFFDNKKYFNFVEKCREAGINVPIIPGLKILT
KKEHLTSLPKTFHISIPYELSSEVEKVTKSEFAEDVGVEWAAKQVEELLNKKVPALHFFV
MKNDEAIHKVMKKIGF
>A0A660C7E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella rugosa|TrEMBL
MRAPRARNRRTARALAPLLARPRYEVLPVRGVLEETGALPEHTVVTVTASPRRGTGATVE
LCEKLAAQRLRPVPHLAARQITGGDELAGVLDRLAGSGVDEVFVVGGDATEPAGPYPDGL
ALLRGMAELGRLPASVGVAAYPEGHPVIDDEALWSSLLSKQDYASYVVTQLCFDPDAIAT
FLSRARERDVRLPVVVGVPGAVDPATLARVGARIGVGDSLRFVTAHHSLVRRLLRPAAGR
DAVLRGLADLMSGSAPSEASDRVGGRRAPVPAGLHFYTFNRVRATARLVTELSDAPREGA
RRAQGGEG
>A0A508SVA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium ivorense|TrEMBL
MTETVSPVSNGHRAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGSTRE
RTHSTITRILRETDLLPAAHLTCVGSSRAEIDEIVDRYHEVGVRHIVALRGDPPAGIGTP
YFTHPDGYQSSAELVAGIKKRHPDIEISVSAYPEKHPEAASFDTDIDTLKAKVDAGANRA
ITQVFFDNDLYYRYVDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAEKFD
GLDNDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPHGAQKA
A
>A0A494W9I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium amiense|TrEMBL
MMSASMIHPNWERPPVHMMDGYSLEITAKDVDALAQASAAILPETPVAITFLPGETLEAR
VDAARQVRALGFEPMPHFSARRLVSGDDFETYLATVVREAGVTRSFVIAGDPAEAAGPYS
DSMALIRTGAFERAGIRAVGIGGHPEGHPNMTAEQTFEVLVAKCREIEDRGMAPLIVTQF
SFDAQPVLDWLLLLRARGIDAPVRIGVPGPAGIKTLMRFAARCGVGASAAVLGKYGISIT
KLLGTATPDRLVDALAKGLGPDHGKVRLHFYPFGGIAKTVEWINDYSARQ
>A0A2E8YCK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichales bacterium|TrEMBL
MVTSELNPPKGTNLEPMFERAESLKHCVDAFNVTDSHAAKMSICPLATSHLLMDRGIEPI
MQMTSRDRNRIALQGDLLGAAALGIPNIVFMGGDPPKIGDHPEATGVFDLMSNDVLAAAN
GLRAGADLHDNELNGSPDYFLGAVVNPGASDLDAEISKMNAKIDAGAQFLQSQAIYDPAS
FENFMNRVSGMNVSILAGIILLKSAKMARYMTDNVPGIDVPDALIAEMEDAEDKGKTSVE
IAARIINQIKPMCQGIHIMPLGWEDKIPALLEAVEAG
>A0A2V1M8G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria rosea|TrEMBL
MTPRPTARPAPPSLSYELYPPRSAASADTLLRTIEELEPTRPDHVSVTYSGDEQRRDSSL
ALLDHLLARTSLRPLAHLTCVGSTRAELEQTVAALVRRGVRGVLALRGDLDPGAEPGELR
HAGELVELVREVEQRHTAALAAGRLAVGVAAYPTRHPESPSFRHDVEVLLAKQRSGADFA
ITQVYFRPQRYERLVAAARAAGVTIPIVPGIMPVTDPRRLRTLCRLAGLAPHPGLAAALE
DAPGPAERHRAGVAFAARLARAALDAGAPGLHLYTFNEHGAALDLLEHVDLPRVPHVPVA
LEDLLLPA
>A0A1F0BG76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC077D04|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKNKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3D3ABA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
WQAIGRLAPLAPDFVSVTYGAGGSTRDRTHACVKRMIDETALKPAAHLTCVAASKAEVDS
VVDDYAAAGVRHIVALRGDMPDMGAFKAHDDGYAGSVELVDALAQRGGFDITVSAYPEKH
PESASLDADIDLLKAKIDAGASRAITQFVFDTDAHLRFRDKLAAAGITIPLIAGIMPTTN
FVGAKRMAEACGAAVPQWLADAYEGLEDDLDTRKQIAASVAIDQCRKLIDEGFGHLHFYT
LNQADLTFAVCRILKLGAAAD
>A0A2E4I7B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MLEIWRGGECQKNRSPQVSFEFFPPKTDALSTSLWSAFQELRLFKPVFVSVTYGAGGATR
NRTHEIVAHIRRETDVVPAAHLTCVGSTRKDIREIAQKYSDAGVSHIVALRGDPALGDLQ
FKPHQGGYSGSVDLIKGLREIDDFEITAAAYPEQHPESXGIQPDMDYLKRKCDAGAVRXI
TQFFFDNDCFXRFCDXVRGSXITVPIVPGILPITNFKQIARFSEKCGATIPASIAKLFET
ASDEPGEAQKIALDIAGEQCLKLLSSGVGXLHFYTLNRADLVSEICRVLGIGVWSAAEPI
LVVPS
>A0A2E3ZNA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MIDNQLFPAGMAANLNVSFEFFPPKTEKMFDSLWASVKRLEPLQPQFVSVTYGAGGSTRE
RTHSTVVRILKDTNLIPAAHLTCVNSTRDQVNEVARAYWEEGVRNIVALRGDPPTGHGNY
IPHPGGYDYAVDLVAGLKRIADFDISVAAYPEGHPQAQSLDFDLEILKQKMDAGADRAIT
QYFFGAEPFMRFMDRAEAVGINIPIIPGILPVQNFSQVMKFNQMSGTTTPVWMAEMFNGL
DDDAETRRMVAAAIAVEQCRQLYDYGIHDFHFYTLNRADLTYAICHILGLRPHKK
>A0A5S4Z514|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rossellomorea marisflavi|TrEMBL
MNTLLDALSENILIADGAVGTLLYSYGVDRCFEELNLSHPEEIINVHKQYIEAGADIIQT
NTYGANYAKLSRYGLQDQVKEINEAAVKLAKKAAKEGTYILGTIGGIRAINQHISLEEVK
RGFREQLYCLLLEGVDGILLETYYDFEELRTVLQIVKKETDLPVIAQVSMHETGVLQNGM
DIKDALGELELLGADIVGINCRMGPFHMVKSLEGVPLPKSSFLSVYPNASLPNYEEGRFY
YAAEPDYFGDISNELRLQGARIIGGCCGTTPAHIKAVKERLISRVPVKEKKVKRQELIKL
KDPLLQKSLLHNKVKEKKTLIVELDPPKHLDTGLFFQGAKALKEEGIDAITLADNPLASP
RVSNDAMGTLVQQKYDLDPLVHITCRDRNLIGLQSHLMGLHTLGIHNILAITGDPAKIGD
FPGAASVYDLSSIELIELIKQNNEGLSFSGKSLRQRTNFSVGAAFNPNFRHLDASVKRLE
KKQSAGADYFISQPVFSCEHLVQIAEATRHLQSPLFIGIMPLISSRNAEFLHHEVPGIKV
PDQARRLMKEAEGDPLQSRAVGMGIAKELVETAMELFNGLYIITPFMRYDMSVELIRHAN
VIEKEKREVPYDHNIV
>A0A7C8M8A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halodesulfovibrio sp. MK-HDV|TrEMBL
MKIIDAIQSQSKPFYSLEFFPPKERKQWESFFATVDRLKALNPLFASVTYGAGGSTQDNT
LEITSRMKHDAGIEPMAHLTCVGASKEKINGFINKLREADVHNVLALRGDCPADETFSWR
DQQFKYASDLVELVSNEHPDFGVSVAGYPAAHPESQTFADDLHYTRVKIDAGSDFVVTQL
FFDVREYFDFVSRLRSNGINKPVIPGILPIQSLGSIRRILTLCGANIPGQLYLSLEEANA
KGGDEAVKEAGLKFAVNQIRQLVDGGAPGIHLYTLNKAEMCLELADRANL
>A0A6G4X523|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces boncukensis|TrEMBL
MAIGISAPRTDRPLTVRELLATGKQSFSFEFFAPKTEKGERTLWDALRRIEAVSPTFVSV
TYGAGGSSREGTVRNTERIATETTLTPVAHLTAVSHSRTELRNVIGQYADAGIRNVLAIR
GDPPGDPTGEWVKHPEGLTYAAELVELVKESGDFCVGVAAFPEMHPRSADWDTDIRHFVN
KCRAGADYAITQMFFRAEDYLRLRDRVSAAGCQTPIIPEIMPVTNVRQIERFAQLSNATI
PQEMAERLRAVEDDPAAVRSVGIEYATEMSARLLAEGVPGLHFITLNHSTATLEIHQNLG
LHDRSPA
>A0A7X7P1V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MTQPTIRELIESRRQPLLSLEFYPPKDPLGFGILGGSIERMRPVHPDFVTCTYGAGGSSR
EFSFAAWELLLRMGFTPVVAHLTCVGASRDDLEAQIHRIHAAGIRNIMALRGDPPRGEST
FTPAPDGLAHASDLVALIKALHPDICCGVAGYPETHPEAPSLADDLRHLKEKLDAGADFV
NTQLFFDNAAYFRFLDAARAAGISAPILPGLMPVASVAQLDRSLAFSRATAPEPLRAALQ
NPDPEAARAAGIQWISRQIDGLIAHGAPGIHLYILNQARTVLHPRLAACLAQWRTPPLNP
DP
>A0A7X7G0V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
TNSFGANRFKLEYYGLADKLEAINGAAAGLAREAAGESVYVAGSVGPCLPPEQALTPANR
DSVADAFFEQTSVLARAGADLILLETFHDIEQLQLAAAMARRTGAPVIASFTVGTLFQRD
ERQRPESEFAKRLEADPNVDAIGINCGMGPADLFHPLRRMMEVASKPVVVMPNAGGPREV
GGRMLYLNSPEYFTEFCKRYVELGARGVGGCCGTTPAHIRMAARAIKTMSGVKEHIAIAA
RPAEQAGVASPRAGCAVATADKSAFAAGLCAGKKATSVELLPPPSGAGLASFLKKCRACQ
DAGVDAINLPDGPRASARMSVMATCFAMMREGLGIEPIPHYCCRDRNLIGMQSDLLGGCA
LGLKNWLFITGDPPKLGNYPDASGVFDLDSIGLARLADNLNHGYDAAGQATGQATAMLIG
VGANPAAVEMEREIERYFRKIDAGAEYAITQPIFDADILLRFLDRIHKYDRGIFVIAGLY
PLVSFRNADFMNRHVPGVTVPDGILERMGRCKSKEDGLKTGAEIAREIRERIEDSVSGFQ
ASAPLGRIDIALEVLK
>A0A7X9G3G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MMTEKELGNALRQALMVFDGAMGTEIYRRHVFTNRCYDELCLSEPGMIADIHRSYVAAGA
DVLTTNSFGANRLNLSPFGLGERVEAINLAAARLAREAADQAGRPILVAGSLGPLNTLGN
TSAERIQCLSEQAAALVAGGVDFLMFETLPSPEAAQEARAAVAALKQPVAFVLSHSVPAD
GDVESAVHHRLADWSASAGPMPAAMGFNCCVGPDQMLSVVEVAVRYCELPLIIQPNAGTP
RNVDHRQLYLCSPEYLTEYARRYVNLGARGVGGCCGTTPEHIREMARAIKPMTKSHVTTP
RADAEKTDAVPEMPLAERSQLGRKLAAKEWVTAVEMTPPRGWDTSQIVARARLCRDHGVD
IVNIPDGPRASPRMSPLITAAMILKQAEIEPVLHVCCRDRNYLGLQADLLGSAAAGIRNL
LMVTGDPPKLGSYSFASGVFDTDSIGLVSLQKHLNRGLDLGGQKIVPPTAAVVGVGADPN
ALDFDREVRRLREKAAAGADYITTQPVFDPDALFRFLDAIDDLQLPVIAGIWPLASLRNA
MFMKNEVPGVTVPDWVIERMTKASTNEEQLATGIAIAREAIEAIRDRVSGVQVSAPFGKV
EIALATLEFRH
>A0A014FG30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_10|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGVRIGGAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKAFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELNVLEELWNSLWQVT
TGKEFSPEIVRFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEILKDKLIPTVSIETRGTSSWKNWYLGAEA
>A0A858BC59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter heylii|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMENLLWESIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATSEELKKIAQDYWDSGIRRIVALRGDEP
KGYDKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHIIT
QFFFDIDSYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPSWLTKAYDGL
DDDPTTRNLVAASVAMDMVKILSSEGVSDFHFYTLNRSELTYAICHMLGVRPSV
>A0A8C1LPQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MKAKSFLTSCIDSNSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGKDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIITQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQKD
>A0A1I3U157|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus mauleonii|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPSTVEMENTLWKSIDRLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKEKTGLDAAPHLTCIDASREELRDIAHDYWHSGIRHIVALRGD
LPNNCDKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATITNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPV
>A0A853FDS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas soli|TrEMBL
MCRSRAPTSRIITGIDAHAARRRVACRASSRFLTKEHQHGIDTCLDFECSGTAYRGLYPA
GYHSGLFRIGPGGGAGAGAAQYAGQACVGAADAAHYHCYAGAVSAGAQRIGLLVRRFGAQ
GLPGQWLLVGAAWRHRLQHRVRSSFKVIELKRSKQAISLEFFPPRDIAAQEKLVRSAKQL
LALQPEYVSVTFGAGGSTRSGTADTVQLLQNLGCSAAPHLSCIGASRAMLTDILDSYRAK
GIRRIVALRGDMPSGMGGDAGELHHASDLVAFIREHSGDWFHIEVAAYPETHPQADGARS
DLHHFVSKVKAGANSAITQYFFNPDAYFDFVDRARAAGVTVPIVPGIMPITNHTQLVRFS
TMCGAEIPRWIRLRLADFGDDRASIRAFGTEIVGRMCQHLLDGGAPGLHFYTLNNAEATQ
GIWRQLRLA
>A0A2N2DCM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-14|TrEMBL
MSENKSRLQTLFEQGEFVVTGEIGPPKSASGAGIREHAKHLSGYCDATNLTDNQTAIVRL
SSIASGVHVLQAGGEPIVQMTCRDRNRIAIQSDLLGAYSLGIKNLLCLSGDHQSFGNHPT
SANVFDVDSLQLIRMVKRMRDEKVFACGEEIKKDEPRFFIGAVANPFADPFEVRVYRMEK
KINAGAQFFQTQIIFDLERFDRFMELARERGLHERSYIMAGVMPVKSAKVAGYMKKFVSG
MAVPDDMIERLKKAEDQQAEAVEICVEQIKYLKNVKGVKGVHIMAVGWEEIVPTIVEKAG
LLPRPQVPGLAQVAG
>A0A1M7Y3M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila aestuarii DSM 18488|TrEMBL
MHDAHESPAPDTPPTSFKIIAELDPPKGTNIQPFLDTALQLKGRIDAVRVTDSEHAIMRM
APYAPCLSLMENHINPIMVINGRDRNRISFQADLLAASALGIREITIKKGHDPAEGDQPV
TRSSGDLDLQTMIKSVAALNGGNDLGGEPLDGSTAFSAGVEIELTDNSSANRQLAETFSY
MADNGIKSVTLGPTYDLNIIDIFLPAAEKTGLKLYTSIMFLKSVTMVKYLNNLPGVPSVP
QEFLKKMMNAPVKRDAGMEIASDLYRDLATLGNGTVLLSIGLRERLPDFLSMIGR
>A0A1K1SUA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sancti|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMTFKPAFINVTYHRSEHMFKKR
SDGSFEKVEIRKRPGTVAICAAVMNHYNVDAVPHLICGGFSREETENALIDLNFLGVDNV
LVLRGDAPKNESSFEPEPHGHRYADELLHQVVNMNNGMYLEEDLQGGVKTKFCIGVAGYP
EKHFEAPNLATDMSYLKRKVENGADYIITQMFFDNQKFFDFVKKCREMGITVPIIPGLKP
MTTRKQLTVLPRAFHVDIPNDLANEILKCKTDKDVELVGAEWLIQQSKELKEFGVPVLHY
YTLGKPEVIRKVVEAVV
>A0A2E5P606|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacteraceae bacterium|TrEMBL
MNNNIKTVLKLLTNYSIETTPNVYEKYGTFADLVPRESNIYITYLPNENMKKVTETAKKL
TLEGYSVIPHLPARTIANHKDLETYIKVLSEYCGCTKILVIGGGGNQKGLIKSSIEVLET
DLLSKYNFKEVGLAGHPEGNPDVSKIDLDKAIIEKNIFSKKADFKMYLATQFFFEAESLK
KWELHLKSLNNELEIHAGIPGPATLKTLISFARSCGIGNSIRFLSKQALNITKLATTNSP
DKLIYDLASYQMENPDTNLKKIHFYAFGGIKKTSDWLKSINKPNLIYNGQKFE
>A0A2Z5UA91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. EG6|TrEMBL
MTSNLNSLAEARRAAASPLFANLEGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLDPSFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASRAEINEVAEAYWEAGVRHIVA
LRGDVPGGEPYRAHPDGYANAVELVAGLKAIAPFEISVAAYPETHPDSDCPQADLDNLKR
KLDAGANRAITQFFFAPDSFLRFRDAAVAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMVSLFDGLDDHPGARQLVAATVAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVSTAKDQAA
>A0A2M6Z7K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium CG07_land_8_20_14_0_80_42_17|TrEMBL
MKISEILASAKGNRPVFSFEFFPPKTPEGEESLYRTIDDLKTLKPDFVSITYGAGGSTRD
KTVEWSRRIKFELGVETMAHLTCVGASKIEILGLLNRLAEIEIENILALRGDPPKGKSNF
MPAEDGLAHASELISFIRSKWNARFSLGAAGYPEKHPEAVDFEIDINYLKAKMEAGADFV
LTQLFFDNKDYYKFIDTLKNKFGGELPCPVIPGLMPVTAADQLKKFAEMCGAKIPEALEK
EVLSAKNKEEVEEIGIAYAIKQAKGLLNHGAPGIHFYTLNKSKSAMKVLGTIKHD
>A0A1H2W415|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marininema mesophilum|TrEMBL
MGAAFNPNVSKMEPAIRRLKRKVEAGADFIMTQPVYDAESVQRVAEATKDFDIPIFLGVM
PLTGHRNALFLHNELPGVKIPDSVLKQMTNKKGAEAREIGISQARGLLDEAIKYFNGIYL
ITPFNYWEMTAELTRYIRGKTNIMQADHQ
>A0A329ZUX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. 15-1451|TrEMBL
MIESVIKSIEQGSFLSFEFVPSLSGSLSAQIQTLKVSGIVEKINAFICTDSPRACLKPSS
ILTSIKLQNALGKPSICTLSMRDRNSLALQADIIAANEFELRIFLALTGDAIRYGNQPQA
KDVFESNSSLLIQIIHALNLGRDLQGNELSGKLKPIYPLCVMNSYATDWEKLKRKMYKKV
ESGVNAIVTQPIYDIQVAEQLLECLHKINHQLGSKTILIIGFYPVISYKSAYFFIPNYRV
FLFQRNGCIGFKKHKHKEKNTKGRLELR
>A0A4U0ZRE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus sp. IMCC35007|TrEMBL
MSFQKRLASNEFAVLAEIHTPKGINITKIVTDAKRLKGRIDAVVVPGMDNGIMRMSALAG
GALLQQQGLEAIIHMYCRDSNRMALQGDALAAHVLGIQNIIVADSADMSESDHNEAMTVN
DLNEIELIKALVTLQNGKDLSGFDLDGSPDYLIGCSLPSIVDDQQLEAALDTARQKIQAG
ARYVITPPVFDVTSWEPTLKKIKSLDVPVIASVFLIKSLAIAQYIANSEPGANIQPEMIS
RIRKSSNRDQEGVAIAGETISALKNSCQGVLIQTLGWEHKLPGILDIAKL
>W7X560|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp. T4|TrEMBL
MALPVSFEFFPPKTPEGAEKLRAVRQQLYGQKPEFCSVTYGAGGSTQQAPSTPWVPSWPR
AWTRLRTFRASVPPRPACASN
>A0A7V9UVM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrinomonadaceae bacterium|TrEMBL
MRNFREILDSDGVFVFDGAVGTRFYDKGIYINRSYDELNLVQPDIVREVHAEYVEAGADI
IETNTFGATRHKLQQYSIENKLREINITGAKLAREAAGEDVFVAGAIGPLDLRIEPYGPT
SFDEAKEMFAEQVSALLEGGVDLFVLETFSDLSEIHQAIKAVKELCDLPIIAQMTIHTDG
KTIFGADAEIITQRLDQYGADVIGLNCGVGPTHILTALEKMRSVTTKKLSAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRFIKAGATFIGGCCGTTPKHIKLISDSVRAVSPRQAKTAKP
TETAKVIDLKPIDVQVVPAEDRSKWSRKIALGEFVTSVEVLPPKGCDAAKTLESIKLLVE
AGVDAVNIPDGPRAQTRMSAQATAILVERDIGIEAVLHYCCRDRNLLGMMSDLLGAAAL
>A0A6G2NQT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4925|TrEMBL
MALGTPSTWTDHAPTVRELLATGKTSYSFEFWAPKTAKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTREGTVRATQQIAADSTLTPVAHLTAVDHSVAQLRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSDDWDSDIRHFVD
KCRAGADYAITQMFFHPESYLRMRDRVVAAGCDTPVIPEVMPITSIRQLERFAQLSNASL
PSSLKERLLAAKDDPAAVRSIGIEFATEFCAELVSEGVPGLHFITLNNSTATLEIYENLG
LHRQS
>A0A7W1BZU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrinomonadaceae bacterium|TrEMBL
IMTDGNTTFGTTPEVFTARLDEWGADVIGLNCGVGPAIILSGLEKMRAVTKKKLAAQPNA
GLPRDVQGRQFYMCSPEYMSKFAKRLIQSGAKFIGGCCGTTPAHIKLISDAVRAASPRAQ
RMVMSSGPLALVEEIVPADIKVVPAEERSNWSRKIVRGEFVTSVEVLPPKGVDAQKTLDS
IRLLKDAGVDGVNIPDGARAQSRMSAMATAVLVEQQIGIESVLHYCCRDRNLLGMMSDLL
GASALGLRNLLLITGDPPKMGPYPDATAVFDIDAIGLTNMVNKLNHGLDIGNNPIGQPTA
FCIGVGVNPGAINPEEEIRRFEYKVEAGAQYAITQPVFDTDQLRDFIKSVEHVRIPIIAG
IWPLVSYRNAEFLHNEVPGVRVTPSIMERMRAASAISKEAGRDEGLKIARESLLEVRDLI
QGVQVSAPFGNVKYALEVFGALEEFSRKEAEVATNRSAEE
>A0A3C0V8D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MTLRESFTGKTFCLGVELVTTRGFADKGPASKVLQFGRALAGRTDIDWLSITDNAGGNPA
LGAEHLGGILRDLGAEVLIHLSAKDMNRNALEGRAWTLASRGLTNVLVLTGDYPIAGFRG
SARPVFDMDSVTLLAMLAAMNAGMEVAAPGRAAVALEPTSFYAGVAVSPFKAHPAELLGQ
YLKLERKIAHGAQFIITQIGYDARKWDELRVHLEERGHRLPCIGYVYLLGKGVAGVFHRN
QIPGCVVSDELLALVERQAAGPDRGKSFFIELAAKQAAILRGMGYRGAYLGGLTSPAQLD
AILERLRSFSPDDWRLFAKELQFPAPNEFYMYERDPATGLADAGRRAPMPRASAPALERL
GFAFNEVFHRIVFAPDAPLFGAAARVYRTLEKRPRLASAARGLENLIKAAMFGCRGCGDC
SLPETTYICPESSCPKRQRNGPCGGSCRGKCEAEDRDCIWVRAFRRCGGAEKFAALLQEA
AAFVDDGLRTKSSWANAFLGRDHHRYREGATHGDSGTHADR
>A0A800MAI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDILRESAEAGRPVISCEFFPAKTPAGEATLIGKIAPRLKAIDPAFFSVTYGAGGS
TRDKTLDIVETLQRDQGVPTMAHLTCVGSTRADIGGFLDEAHRRGVRNVLALRGDPPPGQ
ENFVKPEGGFEFSHELVSFVRDHNDFTIGVAGFPEGHIACAEGREVDWQRLQAKVDCGAD
FVITQLFFDNADFYAFRDFLRARGVTQPILAGIIPILSGGQIQRFTEMCGSKLTPEITDT
LAKLGDDDAAVAEFGVDYATRQCADLIANGVEGLHFYTLNRSRATVQIVQNLNLPPRAS
>A0A8J6U592|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aestuariibaculum marinum|TrEMBL
MKVTDHIKKANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVD
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VVALRGDSRKDEPYFVPTKGGHAYATGLVQQISNLNNGKYLHDEIQVEHNYDFCVGVAGY
PEKHMEAPSLHTDLKRLKEKVDAGADYVVTQMFFDNKKYFDFVEKAREIGITVPIIPGIK
PIAVKRHLQILPQVFKIDLPEELIEAVEGCKDNAAVRQVGIEFAIQQSKELKEAGVPFLH
YYSMGKSDNIKAIASELF
>A0A7C3U7Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MSDGSNGWKSGSTLERVLKGGSFVITAELGPPKNADAEVIRKKARFLKGYVEGANITDNQ
TAIVRMSSVAAGCIALSEGVEPIIQMTCRDRNRLAMQADLLGAYALGIRNVLCLSGDHQK
FGNHPTAKNVYDVDSLQLVQIVKGLRDDKKFACGEEIKGVEPRFFVGAAENPFADPFEWR
PLRLAKKARAGADFIQTQLVYNVEKFKTFMTMVRDLGLDRQLYILPGVGPLKSPGMTRYM
KNEVPGLDVPDAILERMQKTPKEKWREEGIKICVEIIQQMREIPGVAGVHIMAIEWEEAV
PEIVKQAGLYPRPQPPAQAPAG
>A0A6M8WEE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MHIRDIFKQQRTTFSFEFFPPKSAEAAGKLFDTIAELESLRPTFVSATYGAGGSTRELTN
DLVVRLRDETSLNPMPHLTCLGHSESEIHAILERYARHDIGNILALRGDPPRDQPDYDRA
ADAFGYASDLVAAIRRFNDSGTHPNPSGFGIGVAGFPEGHPETPNRLRELDLLKAKVDEG
ADFIITQLFFDNRDFYDFRDRCRLAGISVPIIAGIMPITSAPGMARMADLAQGARFPAAV
IRAIKRTGGDPEAVQRVGVHWATEQCRDLLDHDVDGIHFYTLNRSRATREVYTTLGVRDS
MDLQ
>A0A350G5J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MNITSFLQLLSSRTILADGAMGTMLHARGIGFDKCFDELNLTNPSAVAEIHREYIEAGAQ
LVITNTFGANRFKLSKHGLQEDVVDLNKAGVDLARKVVSASFKDVLVAGDVGPLGVRIAP
FGRVQPEAAREAFAEQIRSLAEAGADLIVIETMSDLYEIREAIKAAREVCELPVVASVTF
TRDDRTLLGDNPTKVARTLHEAGADVIGVNCSGGPAQLLRILKQMNQAVPDGRFWVKPNA
GWPEQVGGRIMYPADAEYFGEYALSFREAGANMVGGCCGTTPQHIATMRKALDTNPPSDS
SHIEVFPQDELAETAQEQPTKFAQKLTGGGFAISVEMDPPRGLSTHKLLAGASLLAEAGA
DVINVADSPMARMRMSAWAVCDVVQRKVDIETTIHFPTRGRNLLRVQGDLLAAHALGIRN
VFVVMGDPTSIGDYPEAMDNYDLVPSGLIKLIKQGFNEGVDHSGTSIGQPTSFFVGAALN
LSPKDMDTEIKNLHRKINAGTDFFLTQPVYRPEDGPRLLESYEKKHGKLDKPMVNVMFA
>A0A2E1VVS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MDSSPSSVTPASAPRLDLRARLALGPLVLDGAMGTALNERGIAFNECFELVQLQRPELIG
EVHHSYLEAGAEGVHTNTFGANRYRLAKFDEGRRLQEVIEAAVQIAREAAGDARFVVGAM
GPTGVEIEPFGRVARDEARAAFRESAAVFAGLGIEAISLETFSSVDELIEAVRGVREVSA
LPLIAHFTVTGAGVTLRGAHPEEVYARLESEGVDVIGVNCSSGPSAVLEATQVLMNCGEL
PISARPNAGMPRQLDGRVFYENNPDYFGRFARRFLQAGGTLLGGCCGTTPEHVRAMARAA
RAVGAQERGERERAAVAATRVREQRPREPKPLAERSTLGRLLEQGLCPVSVELVPPRTPD
TAKLIEVASTLRDAGADLINLPDGPRASARISNSVAAHLIEREAGIETLVHFCCRDRNLL
GMQSDLMGGYALGLRNMLVITGDPPYQGNYPDVTAVFDVDSIGLCNILDNLNHGLDVGGN
DLKGQTHFCYGAALNPTAVDWERELHRYEWKVRAGINFAITQPIFDVEGLLARLPELPPD
GPPILAGVWPLRSLRNAEFLASEVPGVHVPDAVLKRMRAADRSGKAAEEGIAIALEAIDA
LRAHVAGFQLAAPFNKPEAAVALLQSLEGRR
>A0A399ZWK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MTGFTPGRRWQPAYLPFQKETFGERALRVLEYSVKGPLFGCRMCGNCLLAETALICPMEC
PKGLRNGPCGGSTSEACYVDPSRPCVWYHIYDRSFKWGREDVLLEVLPPLDWEKVGKDSW
GAIIRNAHKIGFKKIFTGLLSVKTRSQTLDGILRPVRQPEWWKGDAEYHPPAYMEPASSL
QGRLVAGDFVVTAELTPPLSSSTDKLIRNIELVKNLVTAVNFTDNQSAMPRMSSWACSTV
ALQHGAEPVLQMSARNRSRGSVQSEIIGATALGVRNVLCVTGDSAKMSPSPRDQMDINDL
DSIQMLWVLRRMRDEGKYLDGREIKHPPMFFLGAAASPFSSNVKFQALREQKKVNAGAQF
FQTNLIFDVDGMELWLNELAKRNILDKVYILAGVTPIKSLKMAQKLAEVPGVHLPINVLR
RIEAADRAGNAQEEGIQIALEVINRIKTYDKQGIHGIHLMPVGWDEVIPRIVTEAGLMPK
KYHINAVVRDGIPHTLEMAG
>A0A420N698|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAS
>A0A399YWA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MLRASRNIIMNRTQFKERLEKGPLLMDGAFGTVLHGRGIPIDQSFDAVNINQPALVAEIH
RGYIDAGSELIETNSFGANRYKLGENGLQSKVEEINKAAVAVARRVIAGSFKDILLAGSV
GPLGVRLAPLGRVSPEEAQEAFSEQIHALITAEPQGVDLIIIETMSDVKEIEAAVAATRA
ISADIPIIVEMTFTRDDKTMLGYPPEAVATTLAALDVDAVGINCSGGPAQVLRLISIVRE
VAPDIPVSASPNAGWPEQMQGGRVMYPATPDYFADYARAYVNAGVNLIGGCCGTTAAHIK
AMRHALDTPGEASVSLPRIRITSRRETAVPTGTQPTLLAQHLAGDQLILTVEMDPPKGVA
PERLLAGARMLREAGATFLNIADSPLARMRMSAWAAAYLVQKDIGLETVLHFPTRGRNLL
RIQGDLLAAHAMGIRNLFVVMGDPTRIGDFPEATDTFDIVPTGLVELIKNQFNQGLDKAG
QSIDQPTSFVVGCALSLTPKDIDAELKLLRKKARHGADFVLTQPVFDTKAAVAFIEAYER
TYDEPPPPILAGIKPLYNSRNAEFLHNEVPGITIPEEKRERMRRADQPVGEGVQIAREIA
EELRPYVRGFYIMPAFGRYDLVADVLDVFPKI
>A0A367ZE68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPIFTPGRRWQPPFYPFKKEPLGARLLAGIEKLVKGPLFGCRMCGNCLLQETAFICPMEC
PKGIRNGPCGGSTPEHCYVDETRPCIWYKIYDRAFKMGREEYLLEVLPPLDWNKVGTETW
GDVVKQVRKIGTKNVVTGLLSKDPVKRTVVWDSIFRPVRQPDWWQGDAEYHPPMYTEPIS
ELERRLKAGEFVVTSEVAPPMTVSTNKLLQNIELIKPYVTAINFTDSPSATPRMSSWACS
VMAVQAGAEPVMQIAARDRTRVGLQAEVLGANALGVRNILCLSGDSMRMAPDPRGRMDVV
DIDSIQMIWILRRMRDEGKYLDGRAIKFPPKIFIGAAASPYASEPRFQAIREHKKVNAGA
QFFQTNLVYDIDGLEIWLNALAKRNILDKVYILVGITPLKSYKVAQYMHNEVPGVFIPDK
LMKRMEKAGDGASEEGVQIALELIEAVKKLQGVHGIHLMAVGWEEIVPRIVQEAGLAPKG
APKIEAKTAEVVVNS
>A0A7X7FLW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
LIAVTGDPPHVGPFDRWASRVNDIKSSVELLRLLSLMRSGELLNGQPLPEPVDFCAGCGY
APTTNLTAQTQWLKRKVQAGAEFAFTQPIYMQEDFERIQKATMDLGIPIFVGILPLTSAR
QISYLRSGKIPGISVPEPVEEFILKYDNPADQARAGLDLAEQLIADLAERVSGFYIVMPF
HKNGFEWTANLVKLATTFKTKNAN
>A0A7C3PRU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPNIKFLDLISTDTLLADGAMGTMLHARGVGFDQCFDELNLTNPSAVAEIHREYIEAGAQ
LIITNTFGANRFKLTKHGLQDDVVEINKASVDLAKRVVAASFKEVLVAGDVGPLGVRIAP
FGRVQPEQAREAFAEQIQALSEAGVDLIVIETFSDLYEIREAINAAKQTCKLPIVASVTF
TRDDRTLLGDEPMKVARTLRDAGADVIGVNCSGGPAQLLRLLKQMKQAVPDGKFWVKPNA
GWPEQVGGRIMYPADAEYFGDYALSFRESGACVVGGCCGTTPQHITVMKKALATSEYSPV
LIQTPDIFETSETPDAEPPTQFAQKLGRGEFAISVEMDPPRGLSTHKLIAGASLLADAGA
DVINVADSPMARMRMSAWAVCDVVQRKVGIETTLHFPTRGRNLLRVQGDLLAAHALGIRN
IFVVMGDPTAIGDYPEAMDNYDLVPSGLIKLIKQGFNEGVDHSGTSIGQPTNFFVGAALN
LCPSDLENEIKNLHRKVKAGADFFLTQPVYRPEDGPRLLEAYEARHGKLDKPILVGILPL
VSVKHANFLHHEVPGIFIPDEARKRIEAAGEDGPKAGVEIAVELIDQLKAWAGGVYIMPQ
FHKFDMVAEIIEAVQ
>A0A660W1R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MAANTNFAELLSRRVVLGDGAMGTMLYQYGVFLNSCFDELNISNPELVKKVHRGYVQAGV
DFIETNTFGANDFKLAKYGLAEKVEEINHAAVEIARDTATEDVMVAGAMGPLGYEFTGHG
RLTRPQASRAFRKQAKTLIKSGVDFLILETFSNTEELLVAIRSVSEIADLPIVAQMTVNE
HNETIYGERVEQVIAKIAAEKSVTAVGLNCSVGPSGMLSSLELIRNVTDKPISVQPNAGM
PRQVENRTLYMCTPEYMAEYAKRFFEKGAKIIGGCCGTTPEHIKEIVRVVRSLDKAASPK
AHISKISIEKPAPAVEKAKPLPLAEKSRVGAKLAAGHKVTTIELTPPRGVDTIATLDKAR
LCAELGVDAINIPDGPRASSRLSPLVTAVKIQQNTDIETILHFCCRDRNLIGMQSDILGA
SAIGLRNILIITGDPPKMGEYPNATGVFDLDSIALTAVVKNLNSGIDIGGNHFSPAVRLS
ISVGANPVAIDMDREIQRFKRKVEAGAEFAITQPVFDVDTLFNFLELIEPFKIPVIAGIW
PFASFKNAEFMANEVPGVVVPKQLLGRMGTAKTKEQGRMLGVEIAKEMIEKIKDYVAGFA
VSAPFGNVKTALAVLGKIDIKEIQVS
>A0A7V3TZU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MAEKQPFAEYLAQGVVVFDGAMGTEIYRHHVFTNRCFDELNLSDPKLIRKIHQSYCEAGA
EVLTTNTFGANRETLAKYGLAEQVRAINQAGAQIARQVADAADRPVYVAGSIGPLPTLPQ
NEEVLWQMIWEQVDALLEGGVDFIIFETQPSRQALELCAAAMRERPGVPFILSAAVYEDG
ETASGETVQRLFAPLPEGYPEPLAWGLNCGSGPHGLLGAVEQAVRILRKPLVVQPNAGIP
KEVEHRRIYLCSPEYLAEYAKRFVNLGAAGVGGCCGTTPDHIRAICDAVKPLVRARVKPI
FVGPAETVELKTPVPLAERSRFAWRLVHKQWVTSVELVPPRGYDLRDIIEKSKMLHRHGV
DAVNIPDGPRASSRISPLITADRIQREAMIEVILHFCCRDRNLIGMQADLLACAACDIRN
ILFITGDPPKLGNYPHATGVFDTDSIGMVGVQKRLNQGVDLGGQPIDPPTAAVIGVGLDP
TAIDQNRELDRFRRKVEAGAEFAITQPVFDPDALLRFLDKVQHHGIPIIAGIWPLASLRN
ATFLKNEVPGVVIPDWVMEKMASVTSREDQLKMGIEIARQAIERIRDRVAGVQVSAPFGK
IQVALEVIGA
>A0A6G2P5H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4925|TrEMBL
MHPLDTASASVGTPLLEDFSLEMTGKDVPELEAADGTLPRGTRVNVTFLGNEDPRMRLDA
ARAVKRLGLLPVPHISARRLTSRTDFEQFLAGLRDDGTATHVFTVGGDPALPQGPYDSAL
ALIDSGLLQEHGVRHVGIAGYPEGHPALTDDTLRAALRDKAASLTAHGLTGHVTTQFGFD
PDPVLSWLEDVRDQGITLPVRIGVPGPAGVRRLLSYATRFGVGTSASIARKYGLSLTNLM
GTTGPDAFLRTLAERYDPARHGEVKIHFYTFGGLRATAEWIARFRQDNLV
>A0A7J2HS42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrososphaeria archaeon|TrEMBL
MSGSGSNRTLKSCPKKVLNGPCGGIRRDLRCEVSDLKCFFSENYPEKLILDENFRKRLDV
KPRRPFSRLLSISGKRVAWIAEVPPRIDVLKKWEDLRMLSIDALSIPDNPLGRLHIDPLA
FAARLKERTDMEVVAHLACRDLNRLALKSRILGLGLIGVEHVLALTGDYVKGRAVFDLDS
MRLIYLARLLSDYGVDESGESVGYRPRIHVGAGTNPHILSRIELSRIRRKLEAGAEFFIS
QLVFSEEGLEEILSELRRSNIRVPIFAGFLLNDPEKVSRFARSINLPIEEIPRTAEKLVE
KYLEILRKLRRVYPLTGAYISTLGKVDYLKIWSEYLEGSF
>A0A5C7ZGR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp|TrEMBL
MKLPVSFEFFPPKTPEGAEKLRGVRQQLYKLQPEFCSVTYGAGGSTQEGTFATVGEIIAE
GVAAASHFSCIGATKASVRAQLATLKGMGVKRLVALRGDLPSGYGAGGEFQYASDLVAFI
RAETGDDFQIEVAAYPEVHPQAKSPEADLQAFATKVKAGANSAITQYFYNSDAYFRFVDE
AHKLGADIPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQAYGDDIASIKAFGLEVV
TDLCDQLISAGVPALHFYTMNQSAATTDILSRLKGA
>A0A2D6ZKK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDIHAEKQAAGKPTISFEFFPFKTPEGEATFFGKTLPALMAAKPDYASVTYGAGGS
TREKTLEIVEQIQTEFRLTTMAHLTCIKHTQAEIDAILDEARRRGIRNILALRGDPPPGE
DWSQTEGGFEFASELVTHMNGRGDFGVAVAGFPEGHIDCNEGREVDWQHLVRKIGCGADM
VITQMFFDNADYFRLADYLSEAGVKTPLFPGIIPVANAEQIKKFSAMCGAKLPEAFAARL
NELSADADAVGEYGIEYATEQCRELLDRGAPGLHFYTLNKSKAVLQILSNLGLN
>D4V8D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus PC510|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELAGEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A2E7SPL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDIHAEKEATEKPTISFEFFPFKTPEGEATFFGKTLPALMSAKPDYASVTYGAGGS
TREKTLDIVEQIQNDFSLTTMAHLTCIKHTQTEIDAILDEANNRGIQNILALRGDSPPEE
DWSQTEGGFEFASELVSHIRGRGDFGVAVAGFPEGHIDCSEGREVDWQHLVRKISCGADM
VITQMFFDNADYFQLADYLREVGVKAPLFPGIIPVANAGQIKKFSAMCGARLPDAFAARL
DELGDDAEAVREYGIEYATAQCRELLDRGAPGLHFYTLNKSRAVLRILGNLGLA
>A0A2D9MY82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFXRDIHAXKAAAGKPTISFEFFPFKTPEGEATFFGKTLPALXTARPDYASVTYGAGGS
TREKTLEIVEQIQNDFSLTTMAHLTCIKHTQXEIXXILXEAXNXGIRNXLALRGDPPPGE
DWSQTEGGFEFASELVTHIRGRGDFGVAVAGFPEGHXDCGXGREVDWXXLVRKVGCGXDX
VITQMXFDNADYFQLADFLRGAGVEAPLFPGIIPVANAGQXKKFXAXCGAKLPEAFAARL
DELGDDAEAVREYGIEYATAQCRELLDRGAPGLHFYTLNKSKAVLQILGNLGLA
>W9CLG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sclerotinia borealis (strain F-4128)|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEMVDEALKNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHYIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IITQMFYDVDNFVDWLGKVKARGVSIPVIPGIMPINTYASFVRRCNHMGCKIPPKWSAAL
QEVKNDDAAVRNIGKDLVAEMCRQIIDAGVHHLHFYTMNLAQATRMVLDELSLTPSTQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNIKLWGQPKSIKDIAELFVSYLESGIGSLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMMPELVRRIQHDP
DLTYYAVKKTGDVQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIDSIMDSWYLVNIVHNDFHKSHGLFPLFDGLSVKNLNEPFETSESGD
VHGVRFVDPQTLPLTNGEANGH
>A0A5C9C9J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTEHIQQAKNTLISFEVLPPLKGKTIQHVFDHLDPLMEFKPSWINVTYHRSETAFKKK
VDGTFDKVEVRKRPGTVGICAAIMNHYKIDTVPHFICGGFNKRESEDALIDLNFLGIDNV
LVLRGDAAKNEASFEPEADGHKYAIDLQKQVVSLNNGIYLDEDIQNGGKTNFCIGTAGYP
EKHFEAPNLELDLNRLKDKVDAGADYIMTQMFFDNQKFFDYVKACRDMGINVPIIPGLKP
ITNKKQLSVLPRIFHVDIPTDLSNAIMKCKTDQECEQVGAEWLIQQSKELKAFGVPVLHY
YTLGKPKVIWNVVNAII
>A0A2E6KZI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MAILSSLRASRPTLSFEFFPPKNDLGSEELLETVNELGKLDPAFVSVTYGAGGTTRERTR
EVVQRIIQDTNVPTIPHLTCVGHTKSEISEILSQYSADQVGTILALRGDPPRDQPNYDRE
GDDFKFAGDLVAFIKENSNEFEVGVAGFPEGHPETQNRLTEMDYFKSKIDQGADYICTQL
FFDNHDFFDYRERCNLVGIDLPIVAGIMPITTISSMKRMADLAAGSRFPAKLLKRLSVAD
GDTAAIRQAGIDHAIEQCQELIEHNVSGLHLYTLNKSSATREIANALTF
>R5IQN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella sp. CAG:118|TrEMBL
MSIVDLISDKQSTAFSFEVLPPLKGNSIEKVFNTIDKLREFDPKYINITTHRSEFVYKDM
EGGLYKRISERTRPGTVAVAAAIQNKYQIPAVPHLICSGFTKSETEYALIDLNFLGIYDL
LILRGDKAKHDNKFVPTPDGHTHAIDLQQQVNRFNEGYFLDGSKMSLMDTPFSYGVAGYP
EKHDEAPNPESDLNYLKEKVKAGASYVVTQMFFDNDKYFAFVERCRAEGINVPIIPGIKP
IVLANQLTVLPKVFHVDLPEPLAKELQNCKNDDDAKQVGIEWCTMQAKELKSKGVPSIHF
YSMMATESVRRVAQAVY
>A0A3D5D3K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDILREHHAAGRTPVSCEFFPAKTPAGETALKETIAPRLKAIDPAFFSVTYGAGGS
TRDQTLDIVQTLQQQHGVPTMAHLTCVGSTAADISGFLDDARARDIQNILALRGDPPAGQ
EAFVKPEGGFEFSYELVEHVHARGEFSIGVAGFPEGHIACTEGREVDWQRLKAKVDCGAD
FVITQLFFDNADFYAFRDHLRGQGMTQPILAGIIPILSARQIQRFSELCGSKLTPEITDR
LDALGDDDEAVAAFGIEYATRQCADLIDNGVDGLHFYTLNKSRATLAVAGNLDLAR
>A0A5U3E2C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. arizonae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1G0H1C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_37_34|TrEMBL
MKKHTSYRISFEFYPPKTSDGMHALISAAEELAFVCPAFFSVTFGAGGSTREGTLEMVKT
LQKRTSISIAPHLSCIGSDRTELLTILQQYQSLGVKRIVALRGDLPSGMVSGGEYKFAYD
LVKLIRETMGNHFHIEVAAYPECHPQAKTALHDLFNLKKKYEAGADSAITQYFFNPDAYF
YFLDECSRQGITMPIIPGIMPILQFGKLMRFSEICGAEVPRWLCKRLEAYGDDAESIRAF
GLDVLSHLCEKLLLGGAPGFHFYTLNYAELSLAILTRLNLFTFPQAEASGSH
>A0A358ERZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRLIRDILEEKRSLGETPFSCEFFPAKTPDGEKLLLQNVIPKLLAINPAFFSVTYGAGGT
TRDQTLEVVDLIQKEQEVPTMAHLTCVGSTRIDIGDFLKEASGRGISNILALRGDPPPGQ
DTFIKSEGGFEFSYELVEYIHSENRFGIGVAGFPEGHIACTEGREVDWDRLINKVECGAD
FIVTQLFFDNADFFAFRDYLRARGMTKPILAGVIPILSSGQIKKFTQLCGAKLTKEITTR
LDELGDDNNAVSEFGVEYASRQCEELISNGVDGLHFYTLNKAKPTLEIVKNLGLQK
>A0A1X7FM21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. LAMO17WK12:I1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLATYHPDFFSCTYGAGGSTRDRTINTVLQLE
SEVNIPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARHFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISNMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A011TZ99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. MRS-1|TrEMBL
MSVATATPAAAASRIAGCPKSMAYGPCGGVNADGTCEVHPTPCVFLTRDLPVRWTSPATE
ETPPDAVSEHPSRPATPAGRELVEIAARRPLVFTGFPVRALRADAVRPTAEALAGSVDAV
LSGDAGRSRVQFPPSYRATLIGATGLRVWMGFNARDRNRTALERELLSLRALGVAGVHCV
TGDHTQTGDRPDARPVFDLESTTTLPRAASLGLLTSFAESPAAPPVAERGARVAEKQRAG
GRMCLTQYAGDAEEVAAFVALCRAAGADVPVLAGVPLVVDREGAALLASFHAAKLPSGFI
DRLFAARDVHAEGIRLAVAYGRALLATGAVGGVVIAGGARPGGEAAYAADLATVARELGG
GS
>A0A5M8USJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. ICMP 7243|TrEMBL
MSSKNENGQGGIRISFEFFPPKSEEAEAQLWNTVEELSEWEPEFVSVTYGAGGTTKAPTL
SAVRRMIHETPFTTASHLTCVGATREDTHRVIDDFLATGVRRFVALRGDPPTGVGSAYQP
HPDGYANAAELVAALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRAAGITIPVVPGIMPIQNLTQLKRFAGACGTSIPSWLDDRFDGLDD
NADERAKVAADVAAEQIKDLVRRGIHEFHLYTMNRSPLVSAVLERLGLQRKADARAVA
>W4N8W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium moukalabense DSM 27321|TrEMBL
MHSPLFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGRSSDRTLTARIANTVG
EYGIPCVAHLTAQYLNKDDVDQALNMFDEAKVSGVLALRGDRVEGAEPAGVFEHASDLAA
YIREERPNLKIYGACYPEKHPQSATLEDDIDNLRKKVDAGVTHLISQLFYDNEDFLRFLD
KARAAGIEVPIEAGIMPVMNAGSVRRMARICQSCVPEKLEVMLNRWGGDNTVLKEAGIAY
ASEQISDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>F2K653|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas brassicacearum (strain NFM421)|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDASSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A3N5KU11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium|TrEMBL
MHIRDILQRGQPCFSFEFFPPRTREGAEQLYASMVDLVALQPSYVSVTYGAGGSTRELTH
GLIIRIHEHTGLTVVSHMTCVGASREEIGGILQEYQEHGITNIMALRGDPPKGEGVFRQP
EGGFAHAADLVAFIKKQFPGMGVGVAGFPEGHPETPNRLLEMEYLKAKVDAGADYICTQL
FFDNRDFYDFCERCEIAGIAIPIIAGIMPVTSLKGMQRMAELALGARFPARLTKSLVRAR
DDEYVERVGIHWATEQVRDLVDQGVRGVHFYTLNRSKATVR
>A0A357Z8B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MQVIEHLAKAKDTLVSFEVLPPLKGKTIAYIYEHLDPLMEFKPSWINVTYHRSETIIRTN
AAGVEEKVDVRKRPGTVGICAAIMNHYNVDAVPHIICGGFSKRETEDALIDLQFLGIDNV
LVLRGDAEKGQKTFVPEHNGNKQAIELLKQVVGLNNGIYLDKDIINGSKSNFCMGVSGYP
EKHFEAPSMEFDLQKAKEKVDAGAQYIMTQMFFDNKKYFEYVDACRSIGITVPIIPGLKP
ITNKKQLTILPNIFYVDIPTDLSTAMLAATTDEACEQVGTEWLIQQSKELKAAGVPVLHY
YTLGKPKVVKDVVAAVF
>A0A353F161|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MAILSSLRASRPTLSFEFFPPKNDLGSEELLETVNELDKLDPAFVSVTYGAGGTTRERTR
EVVQRIIQDTNVPTIPHLTCVGHTKSEISEILSQYSADQVGTILALRGDPPRDQPNYDRE
GDDFKFAGDLVAFVKENSNEFEVGVAGFPEGHPETQNRLTEMDYFKSKIDQGADYICTQL
FFDNHDFFDYRERCNLV
>A0A1F3BWJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeromyxobacter sp. RBG_16_69_14|TrEMBL
MTTTTTKFSDALTSGKWVLTAECLPPRSGGAAAVKRLAGELPTGLDAVVVADNPDEIQGS
ALACAAILAGEGRDSVLSMVTRDRNRIALESDALGAASLGIGAVLCLSGAHQSLGVCPQA
SGVHDIDSIQLTQGLKTLTSQGKGFSDRSTDPRPELLLGAVAHPYQRPLELNLLRLRKKI
AAGADFLLTQAVFDLPAFTEWMDAVRAAGLEKKVAIIASVLPLTSLEKAKVLAERQTYGP
VGAAAIARLSKASDPLGEGVAMAAEAAAQLKAVPGVRGIHILSGGHESLAAKVIELAALA
>A0A3L7T996|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MHIADILTRDTTTLSFEFFPPKTDAGWESLYRSIADFATLKPSFVSVTYGAGGSTRDNTH
ALVVRLRRETNLEPVPHLTCFGHTRDEIHAILELYAANGVSNVLALRGDPPGGARILALG
DFSYAADLVGFIKREGERLGVNNGRGFGIGVAGFPEGHSETPNTIVQLDHLKAKADAGAD
YIVTQLFFDNHAFHDWRARCELAGVKLPIMAGIMPVTTAAGLQRMANLAAGTRFPAPLLK
AIARCRGDAEAIENAGIHWATEQCRDLLDNEVAGIHFYTLNKSGATKRIYKTLGVRAST
>A0A353DWP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRQIRDIHQQRKSEGKPAFSFEFFPPKTEKGEEALFGSVLPELQTMAPDYCSVTYGAGGS
TRDKTLDMVERIQKDFGLVCMSHLTCVQATKEQIAQVLQDAEKRNIRNILALRGDPPGGV
GPFEATEGGFAYSKDLVAFIRAHHEMSIGVAGFPEGHIACKEGKEIDWGRLKEKVDAGAD
FVVTQLFFDNEDFLRFRDHMVKELGMHQTLIPGILPVLSTRQIQRFTELCGASIPTPMMQ
RLEDLSEDDAAAAAFGIEYAVGQCEELLKEGVAGLHFYCLNKAHSTLEVARALASHR
>A0A0B4S644|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. WP8|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSIEEIKR
SFREQLYILLNEEPDGLLLETYYDIEEAKAVLQIARKETTLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPLLENSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHISTMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKNAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMAKAGEDKEKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKESNIHVNYH
>A0A7H8V8D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKEMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFNIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGVEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHHPSVQSF
>A0A842VK35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MRGDYKLAEKKTYSKLGEALAKGEFVLTGELEPEKTTDLSHTIHEAKEMAPYVVAANVTD
SPLGIVTINSMAATKIIQDASGLECVWQLTVRDVNKLGIAGMIMGAHALGIRNVLSLTGD
HTALGDMPESKPVFDLDSATLVKLVREMVDTGKINGHEIEHPPTLHVGAAANPNAKPMGA
EVLKIGSKAEAGAEFIQTQVVYDLDKTIEFLTEIKKYKVPVLLGLFPMKSYGIAKGFDTF
VPGVDVPKDILAKWKAIKTDYKTDKAKQKEIYDQANYEFFKPFVTELKKKNLLDGVHCMA
VHYPRIFPKLVEVIKA
>A0A842VZ94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MSRPAYSNLMKAIKDGKFVFTGELEPVKTVSLDYIIHSAEMMKDYVVAANVTDGPQGFAY
INSLVPSMKVQQEVGLETIYQCTVRDRNRIALMADVLAASNVGIKNILTLSGDHAALGDN
PGAKPVYDLDCSQFIDLISHMVDKGTDIHGNDIDGKVEINIGSAVNPNNEGEPLEAEIAK
LGRKVRVGADFIQTQTVFDIDKTKDFLKEIEKFNCPILVGLFPLKNYGIASYFDKYIPGV
NVPKDLMKRLKKTKKKYMPDKKERKKTIADINLDFFRPFMKEIKQNTKAAGIHCMAVHYE
KLFPRLFKDL
>A0A524CPR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAKRPAYSKLCKALADGHFVFTGELEPKKILADGMEEVIHSAKEMKKTDRIIAANVTDGP
QGDAYMCSLVPSFVVQRDAEIEAVWQVAVRDRNRVALFGDVLGGALLGLKNVLVLTGDHT
ALGDNKQGRISYDLDSTQFCELLKKMIDEGTDYSGNEITDGKIEMNYGCVANPNAVGEYM
EPEILKVGRKVEQGIDFIQTQTAFDIDVAKNFINELARYNVPILLGVFPMKSYGIAWYFD
KYIPGVSVPKDLLNALKKAEKDNKGNKPAKYAALDKVNVEFFVPFIEEIKKNSKASGIHC
MAVEYERLFAPLLDKYPDYAKNYY
>A0A7H8V2L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVVPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDVGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHHPSVQSF
>A0A2S4KY01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolypocladium paradoxum|TrEMBL
MDKITDKIAALPAGGEYFSLEFFPPKTAMGFSNLRHRLKRMEQALRPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRRLIDKALDDAKVLGIRNILALRGDPPRHDE
YRNSEDSEDDGSEAFTWAIDLVRYIRRNHGDYFCIGVAAYPEGHAEDSHPLGQSLEHDLP
YLVRKVQAGADFIMTQLFFDIYAYDRFEKTLREHPSGAFRTIPIIPGLMPIQSYQMIKRT
TKLSHAKVPDAILSRLNAVKGDDEQVKMVGVDIVSELVEKVRTIKSRSPGRQGFHFYTLN
LEKAVAFIVERTGLIPDTADNDEAVVDDANPLPPMPQVNGNVSLRARSHSRTSRRHSSVG
SDPHNRVIVGNRHPAHPEWEATGQEAGIPAESINSRANTLAISEGEGVLGREATWDDFPN
GRFGDSRSPAYGEIDGYGVSLHMSVTQAVRLWGHPKTREDINDIFVKHMRGQLTAIPWSE
EELMPESSTIKDRLIELNSKGWWTVASQPAVNGVASSDSTFGWGPANGFVFQKSFVEFFI
PSSDWKTLSDKLNTPEVRDVVCFYAASAKGDFASSDSSGGASNTSPEASTSPEASTNAVT
WGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSDSEKLLSGVREGYWLVNI
IHHDFVEKDALWRLLMG
>I0XQW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira licerasiae serovar Varillal str. VAR 010|TrEMBL
MKKILEIYKTAKAPVYSFEFFPPKTPEGETKLFEAVEELSKVDPGYITVTYGAGGSTRDK
TIRITSELAKKFSLPAAAHFTCVGGNKDEIRVILKQIRESGIENLMALRGDPPKGEDAFK
KVEGGFGYASELISFIKAEGFDFCMGAACYPEKHPEAASLESDVENLKRKVDAGASYLVS
QLFFKNSNFESFLDLIRKKGIDVPVIPGIMPITSFSQIERFRAMAACEFPEKLVSDLEEV
KDRPEEFYKRSIHFSVNQSRELVKMGAPGIHLYTLNQSPASLDIVRELKS
>A0A424R567|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coraliomargarita sp. TMED73|TrEMBL
MALITEQLTKGIAQGPIFSFEFFPPKTESAAAQLLHTAEKLRHSQPDFVSITYGAGGSTR
ERTLHYASTLQDKFGYEIMPHLTCVGHSKEELRSTIQEFKDAGFKRIMALRGDPPKGEHN
FTPHPKGLRHANELVELIRQVHPECAVAVAGYPEKHPEADSPEADLIHLKRKVDAGASFI
TTQLFFDNSVYYRFVENCRDVGIHVPILPGLLSIASREQAMRFCRMCEATFPEALDKNLL
AAGEDPHLLRLAGDQWILEQASDLLQNGAPGIHLYILNQADAALTLHQKLQSSGILPKK
>A0A414EU25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM31-2AC|TrEMBL
MRVDEVFKQAASQGTAPISFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRSHADIATKIDEYRSAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A1Q5PFI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter flavimaris|TrEMBL
MKVTDHFKNANGKTLFTFEILPPLKGENMRTLFSHIDPLMEFNPPFIDVTYHREEYVYKQ
RENGLLEKITTRKRPGTVGICAAIQNHYKVDTVPHLICGGFNKEETENALIDLHFLGIDN
VLVLRGDCVKSEQRFVPEPGGHNYATELIEQVVNMNNGVYLDDEQAYHNGTGFCIGVAGY
PEKHFEAPNLKSDLRWLKKKIELGADYIVTQMFFDNQKYFDFVNRCRAEGITVPIIPGLK
PMTTKTQLTLLPSLFHIEIPCDLAEAIEDCPDNKAAAQVGVEWAIQQSKELMEFGVPCLH
YYSMGKSDSVRKVAEALF
>A0A094PDL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|actinobacterium acAMD-5|TrEMBL
MTQSQPAQFSFEFFPPATNEGEIRLWDAIRELEPLNPNFVSVTYGAGGSTRDRTLRVTER
IVNETKLKPVAHLTCVGSSGTELSEIINLLLSSGVTSLMALRGDPPGGLDKPWEPHPSGF
THAVELVELARELGMKEIGVAAFPDKHPESSSLEFDAEVLAKKQDAGATMAITQLFFKPD
SYFALVDRARAYGCTIPIIPGVMPLTDEKQILKFAQLSGSEMPPEILKYLKEGSTQPVEV
AKRGVEVATNLSAELLAGGAPGIHFYTMNRSSASREVFMNLQS
>A0A4Q3KRG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MSPQTASACPVSFEFFPPKTPEGAEKLRAVRQQLYARRPEFCSVTYGAGGSTQEGTFAAV
REILAEGVDAASHFSCIGATKGSVREQLATLKGMGVKRLVALRGDLPSGYGAGGEFHYAS
DLVAFIRAETGDDFHIEVAAYPEVHPQARSPEADLQAFAAKVRAGAHSAITQYFFNADAY
FRFVDDTRGLGLDVPVVPGIMPILGSTQLMRFSDACGAEIPRWIRLRLLGYGDDTASIRA
FGLDVVAGLCETLRAGGAPALHFYTMNQSAATLALCDRLGLQQG
>A0A7L0GHP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herpetotheres cachinnans|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAQSYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTDVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVMALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7Y5B881|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKITEKIKNSNQTLFSFEILPPLKGKSIDSIFNCIDKLIEFSPAFVDVTYHREEFILKKR
GDGSFDRIVTRKRPGTVAICASIQNKYKVDAVPHIICGGFTKEDTENALIDLDFLGIRNV
LALRGDNAKTESQFNPEIGGNRNALELINQIKNMNNGIYLDEELENPNPTEFCIGAACYP
EKHQDAPNFISDLNYTKRKIEAGAEFLTTQMFFDNSKYFKYIDECKKTGINVPVIPGIKP
ITSRKQLFLLPKHFKIDIPFELSNEIEKAKNDEEVKQIGIDWCIKQCKELKSKGVPVLHF
YTMGVPDITRKIAKEVF
>A0A8C6KZD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius furzeri|TrEMBL
MVNQVQRVDGSWLSCKSDSSGTSNSGGESSKESSRCSTPVLDAVRSDRLRDKMRRRMESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEEEEGGFNHAV
DLVKHIRSEFDDYFDVCVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTF
LTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKREESVFEVFTCYITGQLNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDAVVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRV
NYHIVNVHGRNLTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLKSCLWQVLDDMFELLDAPLETAFRKKKY
LT
>A0A3D3JI17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MTLAESLARGVIVTDGSVAIELARRGLSERPADRYTLTSPAVIERIYAEFIDAGSTLIRT
LTSQANRYALESSMLAARVHEINRKGVWIARSAAAGKAIVAGTMGPTGRYVKPLGPLDVD
DMRSAFVDQASALLAGKPDCILLLSFIDLDELEIAIDAVRSLSAEIPIIASKSFPEDGSV
LAGPFPTSVAHRLTRHGVDVIGSNGTVGPQRMLGIVQSLRVSTVPLIALPDIGIPTIVDG
IAVYNAEPSYVAAAAARLVDHGAAIVGADGGATIEHIAAIADAVRGRVVGSIAPDIKASR
VERTVAERPSETPAFLSALNTGFTATVELDIPRGTDMSSVLEGARYLAAHGVDAVNISDG
ARARLRMSPIAISHIVQQQTSMHCISHLACRDRNMVGLQSELLGAHALGVTSILAVTGDP
THIGDFPGATSVYDVDSIGLVRALGRMNAGSDLFGNPLGSSTNFTIACAVNPAADDMERE
IDRLAAKAAEGAHVAFSQPIFDEDLLERFLDRIREINIRFMVGIIPLRTIRHAEFLHYEV
PGMSIPAWVRERMATAGSDTARATSIGIDIAVAFLDRVKDRIAGVYLMPPFKKYDIAISI
LEQVQPSKVSRAAG
>A0A7V5Q9E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MLVQERENAVQTHEKLHISFEFFPPKTEKMEQALWDAIHRLAPLEPDFVSVTYGAGGSTR
ERTHATVKRILRETSLKPAAHLTCVAASREEVDSVIRGYRDIGVKHIVALRGDPTDGVGA
SYSPHPQGYINAADLVGGIRKIGDFEISVSAYPEKHPESPDIETDFDMLKAKIDAGASRA
ITQFFFDNRVYLDYVEAARKRGITIPIVPGILPVINFTSAARFAAQCGASIPPKLAKNFE
GLDDYPEARRLVAAAIMAEQVADLHDNGIRDFHFYTMNRANFVYTICHMLGMRPTK
>A0A519JGV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp|TrEMBL
MTKRVPISFEFFPTKTDVGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFTIEVAAYPEMHPQAESFDKDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A7V6LS44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MNVLEKIKSAKSPLFTFELLPPLKGRSIDKIYETIECLLEFEPAYINFTSHRNEIVYKEN
ADGSIEKRAVRKRPGTIALAAAVKYKYNITVVPHMVCGGFTKEETENALIEMDFLGINDV
LALRGDAPKGMKRFIAEKDGHEHTSDLVRQIVNMNKGRYLDDTLINAKPTNFCIGVAGYP
EKHFEAPNMETDLANLKLKIDAGGDYIVTQMFFDNAKYFKFVDDCRRLGIKVPIIPGIKP
ISAKSDIELLPQTFSIDLPNKLYQAVKKCGNDDDAREVGIEWATQQTRELIAGGVPGIHF
YTLGRSDNVAKIVKAAY
>A0A6L4YT99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKITEHIDHRNGRTLFSFELLPPLKGENFESISQTIDPLIEFNPASIDVTYHREEIVYKE
REDGLLEKRTVRKRPGTVGISAAIKFKYNIDVVPHLICGGFTREETENALIDLYFLGIHN
LLLIRGDNPAGEKAFKPEPDGNHYALELVKQAMNMNRGIYLEDDIVNANPTGFCIGVAGY
PEKHPEAPNMAADILHLKEKIEAGASYIVTQMFFDNAAFFRFEKACREAGINVPIIPGLK
PLSTKSQLSALPKTFSIDLPEALFREADKCSTNHQIRELGVEWAIAQSRELIKAGVPVLH
FYTMGKSDNIRKIAEAVF
>A0A7U8PX47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella neotomae 5K33|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A431QC87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MNQFRFSRRPDIGDKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTARTVKRILNESSLTPAAHMTCVDASRDQVDAVIREFADMGVRRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVASFSSRCGALVPAWLAERFE
GLANDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A1B7HZD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buttiauxella gaviniae ATCC 51604|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASPDELRTIAQDYWNSGIRHIVALRGD
LPPGGGKPDMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNYKQAHKFATMTNVRVPHWMAQMFE
GLDNDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>R5EUX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:110|TrEMBL
MRITELFDNGEFVVSAEVGPPKGIHIDGMVEEAKKYLAGVHFVNVTDNQSSVMRLGSLAT
CKVLKDAGLNPIFQLTCRDRNRIALESDLLSAAMLGIDNILCLTGDHTKLGDHPQAKPVF
DLDSVSLLHTASLLETGKDLGGNDLVGEPPKFAKGAVVSPCSDSVDAQLVKMERKVKAGA
EFFQTQAVFEPEKFIKFMEAAKQFGKPVQVGIIIPKSAGMCKFMNKNVAGVHIPDELIAE
LQADKEKTKAGITGVEIAARIIRECKPYCQGVHIMSLGWESKVPALLEQAGL
>A0A160HYQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. GW460-12-10-14-LB2|TrEMBL
MASSASLNLADARALLLSPLGPVARAGSNRDAVRVSFEFFPPKTDEAEANLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIITETSLRPAAHLTCVEASREEVDEVIEGYKTIG
VDHIVALRGDPPGGAGIGGAYQPRADGYANATELTAAINRIGGFDVTVGAYPERHPESPS
IDHDIEVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLQ
RMCGACGASIPEWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETAAAQ
>A0A0I9SJC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. BICA1-14|TrEMBL
MTALNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKARAGADSAITQYFFNADCY
FYFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQA
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>G6EHE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium pentaromativorans US6-1|TrEMBL
MTTPIIHPNWARPALNMVDGYSLEITAKDVDSLRAAAPGILPETPIALTFLPGEEFDARV
AAARTARELGFEPMPHFSARRITSPDEFERYLAAVTREAGVKRSFVIAGDPAEPEGPFAD
SAALIATGEFERNGITAIGIGGHPEGHPNMSDEECWRVLQDKCAEVTARGMAPLIVTQFA
FDADAVLAWLKELRERGIVAPVRLGVPGPAGIKTLMRFAARCGVGASASVMAKYGISITR
LIGSAGPDKLVKALEQGLGEEHGPVRLHFYPFGGLEKTVAWINEFARKS
>A0A2W6AA47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MNENPSCSFPRASRTVCSDISVSFEFFPPASEAMEATLWESIKRLAPLGPSFVSVTYGAG
GSTRERTHATVARIVNETEVKPAAHLTCVAAAGDEIDAIVRDYWDIGVRHIVALRGDPQD
GPGTKYCPHPNGYANSAALVAGIRRVADFEISVATYPEGHPESVSAGAEIDVLKSKIDAG
AHRAITQFFFENEIYLRFLDKVRTQGIDIPVIPGIVPVQSFKQTAKFAGRAGATVPQWLA
DRFEGLDDDPQTRKLVAATVAAEQVLDLVDHGVREFHFYTMNRADLVYAICHLLGLRPKL
AQEAA
>A0A537K505|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVIDHINQAKDTLISFEILPPLKGKGISAIYNHLDPLMEFKPSYINVTYHRSEHIFKKK
ADGNFEKVVVRKRPGTEAICASIMNRYNVDTVPHLICGGFSVQDTEDALLTLSYLGIDNV
LVLRGDAAKNETSFEPEPGGHKYAIELLKQVMDLNHGIYLEEELKGTSSTKFCAGVAGYP
EKHFEAPN
>A0A1U8F633|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum annuum|TrEMBL
MKVIEKIQEAIKNDKVIFSFEFFPPKTEDGVENLFERMERMVTHGPSFCDITWGAGGSTA
DLTLEIVKRMQNMVCVESMMHLTCTNMPVEKIDQALDTIKSDGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGIATKEIYENDLAYLK
KKVDAGADLIITQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTK
IPEEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILANGIKQLHLYTLNMEKSALAILMNL
GLIEETKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDEYPHGRWSNAQNP
SYGALTDYQFMRARSRDKKLQEEWAVALNSVEDIYERFKDYCLGKLRSCPWSELEGLQPE
TKIINEKLGHVNTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSQEKLN
ALVEKCKSFPYLTYMAVNKEGNWISNVNQTDVNAVTWGVFPAKEIIQPTVVDPASFMVWK
DEAFEIWSRGWAQLYPEADPSRKVLQQVQNSYFLVSLVDNDYINGDLFSIFKDI
>A0A523FZU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKIIEHLLNAKKTLFSIEILPPLKGDSIDSLFTHLDPLMEFKPPFIDVTYHREEYVYKNR
GNGLLEKKAIRKRPGTVGICAAIQNKYGIDTVPHIICGGFSLEETENALIDLNFLGIDNV
LAIRGDAIKTEPRFVPDPDGHYYAIDLIDQVVNMNKGNYLDEELQNTYPTNFCVGVAGYP
EKHFEAPNMKSDLKYLKKKIELGADYIVTQMFFDNKKYFDFVESCRAVGIEVPIIPGLKP
ITTKNQVNVLPSIFYIDIPEELSEAVEKCKDNQAARQVGIEWSIMQSKELMEFGVPSLHF
YSMGKAEPVYRIAKELF
>A0A7M2SRC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces ferrugineus|TrEMBL
MALGTASIRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGDWVRHPRGLTYAAELVELIKASGDFCVGVAAFPAMHPRSADWETDVRHFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAAGCDTPIIPEIMPIASVRSLERIPSLTNAAF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A4Y3J3E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKT
FPSSVEKIIHYSGKSRDITDFETFLKLTQASGQKNLLLLTGDKLKGHTNSQAGTNRTRYL
ESVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEAL
KQAKAFLNRHRYPQNILACVMPLSLARANFMVKHKIAGIVITPHMLRVLAQEKQDGRTEN
TYKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVE
TKKELVPQLAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASFWENTPAAK
ALLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A4Q2HXU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fictibacillus sp. S7|TrEMBL
MGLLKDLESKILIADGAMGTLLYSYGTDCCFEQLNLSHTEQIQSIHQAYIQAGANVIQTN
TYSANYIKLQRYGLEEQVKELNSAAVSLAKKAAGGKAYVLGTIGGIRGTGPSSLSLEEIK
RSFREQLYCLLLEGVDGLLLETFYDLEELEAVLKIARSQTDLPIISQISLQEVGILNDRT
PVNTAIKRLEELGSDVVGLNCRLGPFHMIKTLEEVEIPKHAFLSAYPNASLPSYVDGKFQ
YEGDAEYFKNSASLFRNQGVRLLGGCCGTTPAHIEAFAEELNGLSPVTEKNVRQRPEPIA
VASSGQKPQISLPEILQERRSVIVELDPPRKLDTTRFFEGAKALKEAGADAITLADNSLA
SPRICNTSLSSLAKAQTGAQPIVHLACRDRNIIGLQSHLMGLHTLGLHDILAITGDPAKV
GDFPGASSVYDVTSIELIKMIKQFNEGVSLSGKDLGEKTHFTVGAAFNPNVKALDRAVQR
AEKKIEAGADYFISQPVYSEEKLLQFHEAVKDLPVPVYVGIMPLTSSRNADFLHYEVPGI
KLSDEVRNRMAEFKDDPLAAAREGLAISKSLIDAATELFNGIYLITPFMRYELTVELTRY
AYNIAPQIVRRIQNV
>A0A3M8H898|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus halotolerans|TrEMBL
MGLLEALKSKVLTADGAMGTLLYSYGLDNCHEEMNIIRPDVIEKIHGEYIAAGADVIQTN
TYGANAIKLARYGLESKVVEINEAAIALAKKAANGGQFVIGSIGGIRGVRKSDTTLEEIL
TAIREQATVLIDGQIDGLLLETYYDFKELSETIKMLRSITNMPIIAQVSMHDPGVLQNGL
KLNVALQQLEKIGADIVGVNCRLGPHHTIQAFEGVELPERAFLSAYPNASLLAIEEGKVI
YESEADYFARAAVQLRNQGVRLIGGCCGTTPKHIEAAKKLLVNLNPIITKEAKPIQEIVI
QEAEPRNAEPLHEKVKRERSIIVELDTPRHLEINTFVEGAKALYNEGADIIMMADNSLAS
PRVSNIAMGSILKLQHNIRVMPHITCRDRNLIGLQSHLMGLNAVGLHDVLAVTGDPTKVG
DFPGATSVYDVSSMELISLIKQLNEGISFSGKVLRKKANFSVAAAFNPNVRVLDRAVSRL
EKKIEHGADYFISQPVYSKEKIEEIYEATKHLDTPIYIGIMPLTSFRSAEFLHHEVPGIK
LSDEVLERMEACEGDKVLEAKEGVAIARELLDTAVSRFNGIYLITPFLRYDLTIQLMQYI
KQLDEQNKGVKVNA
>A0A1G2ZK77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RBG_16_43_13|TrEMBL
MNQTNFISHLSSQVLIGDGAMGTYIYTKGIPLGRCFDELNLINPHLIRFIHKEYIDAGAD
LIETNTFTANRLRLKRFELENKVKDINYQGARIARGVAGKSIYVAGSVGPLTGAKTDDDI
SLDEKYDVFAEQVLALAEGGCDVFILETFTDLDELKYALRAVKEKTNLPAICQMTFSENM
KTPLGVSVIKALVELEKAGADVVGANCGVGPLATLKVLEEMCKSSKVKVSAFPNAGMPQY
VDGRYMYLSTPEYIAGMAKRMVQAGANLVGGCCGTTPSDISAIAQKLRGIPPIPRHISRR
QMLKTVEEVSLFEPTEKKKTFLDKLGKDIVVVAEVDPPKGMGIEQTLKNAVKLKRAGVDA
ITVGDNPLAVLRMGNIGFSHLIEKKGIQTIVHLSCRDRNLIGIQSAIMEASALGITSILA
ITGDPAKVGDQPAATSVYDLNSFGLIKLIKQMNNGKNYAGNPIQHPTNFSIGCAFNPNVQ
DIDTAIRRLVRKIEAGADFALSQPFYDISRIGEIYDKLGKTVGKFPVFFGVLPLVSARNA
EYLNAEVPGIKIPEAVINRMKETSQDKQLTEGITIAKELLDEAIKYAPGIYLILPFGRVD
IAIKIVEYLKTRKLEVAKVKR
>A0A0Q1BHB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda eckloniae|TrEMBL
MKVTDHIKNAKGKTLFSFEIIPPVKGRNIQELYNNIDPLMEFNPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTLGICASITHKYNVDTVPHVLCGGFTREETEYLLVDCHYLGIDNV
MALRGDAMREEKYFEPTNGGHKFASDLVHQIQEINCGNYLHDVIETDNCANFCIGVAGYP
EKHMEAPSLKSDLKRLKQKVELGADYVVTQMFFDNQKYFEFVEEARKMGIDVPIIPGIKP
IAVKRHLQLLPQVFRVDIPQDLVDAVESCKTNKEVRQVGVEWCIEQSKELKEAGVPVLHY
YSMGKSDNIKAIAKQVF
>A0A4Y4GLT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia marina|TrEMBL
MTSRLTIPDNTQPPPTERDGNVGHLERVLRSGQFAVTAELAPPDSADPQEVHARAQLFAN
HVDAMNATDGSGANCHMSSVAMCALLAREGYETVMQISCRDRNRIAIQGDVLGAAALGLR
NLLCLTGDGVQVGDHPEAKPVFDLDSLSLLEIVAGLRDKHAFASGRSLTSAPQVFLGAAA
NPFAPPFAFRPHRLAKKIAAGAQFIQTQYCFDLPRFQDFMHHARDLGLVEKCFILPGVGP
LASARTAEWMRRHVPGVHIPDDVIKRLKSAKDQKAEGRDLCIEMIQQLREIEGVSGVHIM
AHRQEALVPEIIQRADILEARIPWTPEPRPTPSP
>A0A1Z8ZCD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrionales bacterium TMED79|TrEMBL
MSAAKSLLKSLYFEVIPMKGFEEKLGVLKAGDRVGITCSPKQGLQVTLDTVAQLSDRGFS
LTPHLAARQVMNKQHLKDIVAQLTDSGITSIFVPGGDLDEPMGEYDSSAAVLRDLSEMDH
PFTRIGVASYPEGHPAISDDLLFEALAAKQGIATHMVTQMCFDMPVLIKWLSDMRDRGIT
TPVWIGLPGVMDRMRLFKTSLRIGVGQSAKYAKKQKGLIGMFLRSPTYKPDSLFKELQPA
MADERMAIEGLYMFTFNQIDNTVQWSQEQLKRLG
>A0A2E8YYJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp|TrEMBL
MVSGRGRSMAELLGAGERSISFEFFPPKDEAGAEQLWKAINDLEPYAPTFVSVTYGAGGS
TRDKTVEITGRIARETSLTPMAHLTCVGHTVEELQKILDSYVEAGVHHLMALRGDPPDGP
QAPWTPTEGGLTYASELVELARSRGDFRIGVAAFPEGHVLADSLDADADVLAAKHQAGAE
FAVTQMFFRASDYVDLVQRLRERGCDMPVLPGIMPILTLAAIERQGELIGTAVPAEVVER
LSQYDDRARIREEGIAIAAELCQELLDAGAPGLHFYTLNRSRATLEIFERLSLGPA
>A0A4V1XSV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus sp. 5C6A|TrEMBL
MQIQEMVADAERTGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYFGLETCMHLTCTDMGEEKVNDALAKAYKAGCTNILALRGDPPREKEK
WVATEDKFQYARDLVAHIREKYGNHFGIGVAGYPEGCDDNKDEEQLLDHLKEKVDVGATF
IVTQMFYDADNFVRWMRKVRERGINVPILPGIMPIATYASFLRRANHMNCKIPESWMTAL
EPVKNDDAAVREVGKTLVAELCRKIMAAGIVHLHFYTMNLAQATRMVLEELDWLPTTTRP
RKQALPWKQSLGLGRREEDVRPIFWRNRNKSYVSRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKKWGEPKSIKDIATLFVRYVEKDLQTLPWSEAPLTAEADSIREDLIK
LNQRGLLTVNSQPAVNGAKSSHPVHGWGPPNGYVYQKAYLELLVPPELFPEIVSRIHNHP
DLTYYAVTRTGALKTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAYRLGKDW
AHCYDANSPSRVLIDKIMDEWYLVNIVNNDFHQPRTIFEVFEGLHVDNLDVHNTPGSNGV
HNESNGNAGHTNGSDSAAVA
>A0A368XKE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter nauticus|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHRQGISTAPHLSCVGGTREEIGELLDVYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIRQHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEQMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTDMCEKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A6N7XMP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mogibacterium kristiansenii|TrEMBL
MEQLTFREELSRGTMVFDGGMGTYFSASEKLPGQGCEMANIEKPLLISAIHREYLEAGAR
AIKTNTFSSNRVAYPGGNDVVLRQIRAGFRLAGRTAEAYGAHVFADIGPVTGLDEVRTKE
EYRYIIDAFLELGAKNFLFETNSNTIGLLESARYIRSRVPDAYVIISYAVLPGGYTRDGL
FGEDLLQETGASPFVDAVGLNCISGVRQLQSLLEQMNTEGLTLSVMPNSGSPVVIQHRTI
YQSDPEYFGRELAELAAKGVTIVGGCCGTTPKHIAALTEALKSVSADGTLRSVPRAAAPE
MKESAFFRKLRQGEKPIAVEFDPSGYADIGKYIENAKGLCDVGADVITIADCPTAKARMD
SSLVACMLRREGIEPLPHLTCRDRNLNASQALLMGLSAAEVQNLLIVTGDPIPTAERDEV
KSVYQFNSRKMTHFIRGLEKKGAIHPFHVFGALNINAINFDAELGRAEKKIEKGMQGLLT
QPVLSRRGLENLRRAKTSLNCYILGGIIPVISERNARFMNSEVNGIEVEEALIQRYVGLN
REEAENLALEVSVEIGKAIARSADGFYVITPFNRVSLVSRIVEAIRDGHVIS
>E5WMP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. 2_A_57_CT2|TrEMBL
MSFLNKLKNEIIIADGAMGTLLYSYGTDSCFEELNLSQSEQIQHIHEAYIGAGAELIQTN
TYAANYLKLQRYGLEDSVKEINSAAARIAKKAAKERAYVAGTIGGIRGFKPNMITLEEIK
RSFREQLYCLLLENVDGILLETYYDLEELETVLAIARKETDLPIIAQVSLQEAGVLQNQT
SIADALAKLEGIGADVVGINCRLGPHHMLKTLESVPLPKHAYLSAYPNASIPAYTDGKFH
YEGDAEYFRQSAIEFRNQGVRLLGGCCGTTPDHIKAFSDVLKGLPPIEEKETKAINKVMV
SEKPSSSRELPPLQDIVRERPSVIVELDPPRKLDTSRFFEGAKALKEAGIDSITLADNSL
ASPRVCNSALGYLVKQQTGLRPLVHVTCRDRNIIGLQSHLMGLHALGLNDILAVTGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSFSGKDLGQKAAFSVAGAFNPNVRSLEKAVG
RLEKKIEHGADYFISQPVFSEEKLLEVHEAVKDLKAPVYIGLMPLTGSRNAEFLHNEVPG
IKISDSIRNRMASLKDDPAQAGAEGIAIAKSLIDAAAELFNGIYLITPFMRYEMTVELSN
YARETTERLSRRKQHA
>A0A6P1IRE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp. BPS33|TrEMBL
MGLPISLEFFPTKTPEGAVKLRAVRQQLYALKPEFCSVTFGAGGSTQDGTLQAVTEIMGE
GVPAAPHLSCIGQSRESIRERLAAYKAAGIRRIVALRGDLPSGYGMGGEFRYASDLVAFV
RAETGDTFHIEVAAYPETHPQAKTPQSDLDAFAAKVKAGADSGITQYFFNSDAYFRFVDD
LQGAGVDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRMRLQAFGDDTASIKSFGLDVV
SDLCDRLRAGGVPGLHFYTMNQSTATTDIVQRLGL
>A0A1J6YKB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. houtenae serovar 50:g,z51:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7U8X1H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli FVEC1302|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2E2RII4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MEPSGXATQDLRSMLEGSDRFLTAVEIETSRGLLMAETSRKTAELAKSLSEFDRVDFVAL
TDNPGGNPHIRPEXLGQDLVFRGRDVVINMSCKDYNRNGVESRLWALGSQGFTNVLALSG
DYPTGGXQGQAQPVFDIDSXGLLEXIEQMNEGLPNRVWGSVGREDRLETTSFYAGCAVSP
FKKLEGELMTQYFKLAMKVRTGAKWAVTQIGYDSRKLGXLXQYVQSTGINIPLIGSVFIL
TAPAGRFFNNWGMPGVWVSDELRDIANEQARSKDRGRAFFSELAARQIAILKGLGYRGAX
ISGRPQLERIQHILEMVDSYGXNDWKEFAKEIKFAQDDXFYYFEQGDHPGLSSDAVNKEY
LASKSRSKLGRARARMTVPLQYRXGKFVHDRVFTEGTLGFKAGSAIYXQVEKSKKLTXVX
HVLEQASKVPXYHCRDCGDCSLPDVAYLCPESECVKNQRNGPCGGTKAGMCEVLDKECIW
LRAYDRLKPFGQEEKMLERPVVFRDASLXNTSAWANTFLLRDHHAKRNPADRLGEA
>A0A7C6TF43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTPSGAKQTKSGSRLERILNSGAFAVTAELGPPKGTDVAAVRAKMELLRGVCDAVNITDN
QTAIVRLSSVAASALLCQEGLEPVMQMTCRDRNRLAIQADVFGAVALGVRNLLCLTGDHQ
CFGNHPAAKNVFDLDSIQLIRMIRRLRDERVTEEGDAVEGEVPIFIGGAANPFGDPFEMR
VIRLAKKVAAGVDFIQTQCIFDLPRFKEWMRRVVDLGLHERVHILAGVMPLKSAGAARYI
NRNVAGITVPDAIIRRMAGAGCGAKARAEGMRLCAEMIQEVREIEGVHGVHIMAVEWEEA
IRPITEMAGVLPRPEL
>A0A6N6L284|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAKNKFLALLEKDTPLIADGAMGTILHGRGEGFEGCFDALNLDNPALVADVHKAYIDAGA
QIIMTNTFGANRYKLAEHGLEDKVEEINCAAAQLAKRVVEASFKDVLVAGDVGPLGVRLV
PFGRVQLEDARAAFKEQIKGLADCNVDLIIIETMTDLYEVNEAVLAAKEVTDLPVVASMT
FTRDDRTLLGDDPAKVARRIADAGADVIGVNCSGGPAQILRILKQMREEVPEARFSVMPN
AGWPEQVGGRIMYPAAPEYFGEYALAFRHAGASLIGGCCGTTPQHVTSMRTAIEETAVED
YSNGMQIIGARTPDPVTDASTPSQFSLKLADKQFAVAVEMSPPRGLSTHKLHAGAGLLAD
AGADVINVADSPMARMRMSPWAVCELVQNEVGIEATLHFPTRGRNLLRLQGDLLAAHSLG
VRNVFVVMGDPTAIGDYPEAMDNFDLAPTGLIKLIKQSFNAGVDHSGSDIGSPTNFFVGA
ALNLTPQDPDREIKVLRRKLANGTDFFLTQPVYQPEKAVEFLDYYAKKYEPLEQPVLAGV
LPLYGARHAAFLHNEVPGINIPETTRDRMEAAGDDGPNEGVQIAIELVEQLRGFASGIYI
SPAFGRYDLVANLIEAVKDKEAVGN
>A0A6L9IPX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPIFTPGRRWQPPFMPFKREPRASRLLAYLERRVKGPLFGCRMCGNCLLQETAFICPMEC
AKGVRNGPCGGSTEECCYVDETRPCIWYHIYDRAFKMGREEKLLEVLPPLDWDQVGTETW
GDVWHQMREVGMGKFFGGMLSRKAAKRAATWDSVFYPIRQQDWWQGDSKYHPPGYEEPLS
ELERRLKAGEFVVTGEVAPPMSTATGKMCRMVDLVAPYVAAVNFTDNPSATCRMSSMSCS
IHALGRGVEPVMQIAARDRTRTGLQSEVMGASSLGIRNVLCLSGDSGRMGPPPMGRLDVV
DLDSVQMIWLLRRMRDEGHYLDGRPIKFPPQLFIGAAASPFASRPEFQALREHKKINAGA
QFFQTNLVFDPDGLDVWLNELAKRDVLDKVYILVGITPVKSLKMAQYMDRDVPGVSIPQP
LLKRLEDAGDGVQEESVAITLELIEAIRQKEGVNGIHLMAVGWEEIVPRIVTEGNLLPPD
FKVPEEAESAGAEAGQAATS
>A0A535SN15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQHDFLEQLQQRPLLCDGAMGTLLYARGIAYERCFDEFNLTRPALIQGIHSEYISAGAQI
IETNTFGANRAKLEAYNLEGRVRDINRHAVKLAREAREISGQSVFIAGAVGPSGRPLQAP
DEQRLSELRAIFREQIDALLVGGADLLILETFSSLAELRQAVLAAQDVGGLPIVAQMSFY
EDGHTLSGQSPARVAAVLNDLGIDVMGANCSVGPAATLDVLQEMIAAARLFLDNEQAIPQ
MFSAQPNAGLPTRIGNRFFYMATPDYFADYAVRFARAGVQLIGGCCGTTPHHIAAMRKAL
NDAYGAATPSIPGSSRETLHTKPVEITNGKVTIAGLIEEEVILPQQGTKTRLQEKLAARE
FVVSVELDPPKGLNPAKILEGAAMLQKVGVDCINIADSPMARVRMGCIALARLIQDHLGI
ETIIHFTTRDRNLMALQSELLGAHALGIRNILSLTGDPLHV
>A0A178XGA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium saheli|TrEMBL
MNERTLHPAECGSLRLSFEYFPPKNEEMETQLFRTVGDLSAFAPAFVTVTYGAGGSTKAR
SLTAVKRMIKDMGLHNTAAHLTCVGAPKEEVDAVIDEFLASGVRHFVALRGDPQGGIGSA
YQPFPGGYENAAALVKALRARGDFEISVSAYPEKHPESRDVAADIDMLKGKVDNGATRAI
TQFFFDNDDFERYLERVRDAGIGIPVVPGILPINNLAQVQKFAGLCGARVPESIVSRLGH
LDERPEERFREATHIAAEQIVDLVRRGVTDFHLYTMNRSPLVAAVCDLLGVERRQTAALD
RAERPTQVAASA
>A0A7K2G0I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4950|TrEMBL
MALGTASTRTDHARTVRDMLAAGETTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATERIAADSTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPEGLTYAAELVRLIKESGDFCVGVAAFPERHPRSTDWDTDIAHFVD
KCRAGADYAITQMFFRPESYLRLRDRVAAAGCETPLIPEVMPVTSVKMLERLPQLSNAAV
PSVLKERILTAKDDPAAVRSLGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHPPRA
>A0A3L7XUM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKSINLQELLRRGTLLADGALGSELYARGVVHGSCLDALNLSDPAAVLGVHASYLQAGAD
LIETNTFGANPFRLASHGHGEQVAAINQAGVALARQAAAASGRAVAVAGSVGPLGVRLAP
FGRVKPEAAYTAFSAQIGALLAAGVDALVLETFSDLMELSEAVRAARDCAAAHSPVLLVA
SMTFTRDDRTQLGDSPAHVARTLAGLGVDVLGANCSIGPAQLLRVLQAMHAAAPQLALSI
MPNAGMPELSGGRVLYPAGPDYFAQLTPDWLATGARIVGGCCGTTPAHIAALRQALDTPR
KAAVHSVPHRPSTPAELLPATDAPTKLATKLQSQQFVITVEMSPPKGYTPHKVLAGAHML
AESGADVINVADSPLARMRMSPWAVCHLIQQQVGIETVLHFPTRGRNLLRVQGDLLAAHA
LGVRNVFVVMGDPATIGDFPQAFDTFDVAPTALLQLVKQRFNAGVDQAGQEIGQPTSFVA
ACALSLSAPDPAREIKLLRKKLECGADFALTQPVFDAQVARDFFARYAAEHGPLQLPVLV
GVLPLYSERHAGFLHNEVPGIHIPDEIQRRIAGAADAPAEGVRIALELLAELRATTPIRG
AYLQPPFRRYELAAEIIEHTRAQD
>A0A1W9P3C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium 4484_214|TrEMBL
MSGFKEFFAEADFVLFDGAVGTQIYARGVPKGHCYDELNLSLPETIQEIHREYVEAGAQV
ITTNTFGANAFILEEYFALGDKTREINYYGARLARQAVRGRAYVAGSIGPVTRPLDTDKK
IDFQDLRAIFQEQIEALLEGGVDLLVLETFADLDELLLAIQVARQVAPDIFILAETSFPN
NGLTLFGKNPYEVGFALEKSEADALGSNCGTGPQSVLETIKKMARVTRKPLSAMPNAGLA
QFVNGKFYYPFNPEYFVRYGQKLLQAGVKILGGCCGTTPEHIRRMAAELKGLKPHSRSLS
LIGPVTTTAPKVYKERIETQYKTQVEKGWAVSVELDPPKDPNIDKFLKKIERIAPYIQAY
NISDCPMARARMSSIATGNIIQQQLQKEVVIHYTCRDRNILGIQSDLLGAAALGLNNILT
LGGDPPAVGDYPFATGVYDLTTEGLVQLCSALNHGRDLLGNPLGRPTHFYIGVGYNINDQ
SLPAFNSLVKKSLVKKINQGAHFVVTQPVFNLASCWPHLEELKKKNIPVIVGALPLTSFK
QAEYFHYEVPGIIIPEKFLARLEKLKAKEAEKEGVKITIELINELKPAINGILLMISFNK
LYLLEEIMAKI
>A0A3A1NQC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda taeanensis|TrEMBL
MKITDHIKKANGQTLFSFEIVPPVKGKSIQELYNNIDPLMEFKPPFIDVTTSREEYIYKE
KDGLLDKKLTRTRPGTLGICASLKHKYNVDTVPHVLCGGFTKEETEYLLVDCQYLEIENV
MALRGDARKEEKYFTPTQGGHQYATELVKQIQDINEGNYLHDTIETSDLSSFCIGVAGYP
EKHMEAPSLQSDLKRLKEKVDLGADYVVTQMFFDNQKFFAFVEAAKEMGINVPIIPGIKP
IAVKQHLQLLPQVFRVDIPQDLIDAVEACKTNQDVRQVGVEWAIQQSRELREYGVPVLHY
YSMGKSDNVEAIAKELF
>A0A535HCQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSALASLLGSGEFVVTAELNPPKSAAAGLVRRRAEALKGVVDAVNVTDSNRAMVAMAAIP
AATLVRSVGLEPIVQMTGRDRNRIALQADVLGAAAIGIENFVFMSGDDPKQGSHPEAVFV
KDLDGVGLVKMAVGMRDLAHFLSGDEIKQPPKMLIGATASPFAKPMESDVTKTLDKIAAG
ADFLQTQPVFDLATFSRWLVEVRRGASREVPTIAGVLILRSPEQAERLAKVPGVAIGPEV
LDRLKKADDAESEGIAIAVQMVKALRALPGVRGVHLYAIEWPEAVVRVVDAAGLLPRPDA
RVVA
>A0A2E5F3X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MCTSYLIFLIEILHGEESLTSISGLLSQGTTFSFEFYPPRTEKGAKQLMTTMEHLLPYNP
SFISITYGAGGSSREQTLEIVKELKYNTRSTILPHLTCIGHTRNEIEELVNQYVDIGITD
ILALHGDQPRNSAPLTEGDFKFATDLIEFLRINYDLSLGVAAHTEGHPAASSYSTDLEHQ
SSKIRTADFAITQFFFDVNHYILFREEMKKRKVFIPIIPGIIPVTNPAEIDRMIRLAGGT
FPQKLWEEINNASDQESKQRIGINHSIQLVKQLLKAGAPGIHFYPMNRWQETEQLLQYLD
FNSH
>A0A536GND8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MHIAEMLSRGRPTVSFEFMAPRDENEVEVLEKTVATLAGHAPDWVSVTYRLRTGEQTLQL
VTRIKRQYHIEAMAHLTCANPRDETRRILNWMEREGVANVLALRGDPPGPGEPFQPTDPG
LEHGSDLVAFVRGNGYRLGIGAACSAEKHPESPDLEHEFRYMRLKVEAGADFLITQLFFD
NRFYFDLVSRARAAGIKVPIVPGLMPIPSRRSLAFVTQMSGATVPEALQQLIDGQPDDEG
IRKVGVDHCIKQCAGLLEAGVPGLHFYTFNRARAATEILGTLRGQQLLAS
>A0A3G8UCY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens|TrEMBL
MRVDEVFKQAASQGTTPISFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLACVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A534Z0A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIAKLLARGRPTISFEFMAPRDEAEVDVLERTVSALAGHAPDWVSVTYRLRTGRQT
>W9THI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. BAY1663|TrEMBL
MLHALSSLRLKQSKELLMTSANRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCT
YGAGGSTRDRTLNTVLQLDSEVKVPTAPHLSCVGDSKQELRQLLNIYRDAGIKRIVALRG
DLPSGMGLANGELRHASDLVEFIRVETGDHFHIEVAAYPEMHPQARSFEDDLANFVHKAR
AGASSAITQYFFNADCYFYFVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRW
VRKQLEAYGDDIDSIQAFGEQVISEMCEKLLVGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3S1NHL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.09.1.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A536BNM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPAPSRLAGLLRAGRFVVTAELTSTNSADPEATWRLAEVLRGSVDAVNCTDNTGAHVHMS
SLAAAHLLVEKGIEPIMQLTVRDRNRLALQADLLGAAALGVRNIVLMSGDDVTAGDHPEA
R
>A0A536DD30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MIAGPPAKPSRLRLDSASREALRRFLSHPRYEVLPSEEAGDLVVRNVPTEVTITVTSSPR
RGIDATLALSEKLAAGGYAVVPHLAGRLVRDESHLKEILARLDAIGGRVFVVAGDSQEAA
GEFPDSISLLDAIAGHAPAMKEIGVTGYPERHGFIDDDLTIQAMWDKRRQATYIVSNLCF
DVRVVKNWVARVRKRRVPLPIFIGMAGVADPAKLLRVSTRIGIADSARFLRGHTNWLMRM
IQPGGYAPERFATGLMPELARPDMKVAGIHVFTFNEIEPTEQWRQQMLARLR
>A0A2D7B073|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp|TrEMBL
MSPLSSLQSSDAPSVSFEFFPPKTEAMAARLWETVERLEPMAPNFVSVTYGAGGSTRERT
HDTVRRIAQDTHLRPAGHLTCVGATKEEVLSVAEDYWQAGVKHIVALRGDPPAGMGXKFE
QHPGGFRDSIDLIEGIREHRPDLGRCFEISVSCYPELHPESRGWDAEIAFLKAKQDAGAD
RAITQFFFEPEIYLNFLEKARAGGVTMPIVPGIMLQPNFKGLKRISGLCGSSLPGWLHEL
YDGLDEDTETRELVTANVAADLCRKLSDEGVRDFHFYTLNRAGLALSTCRLLGLKPNSAE
AA
>A0A2D8MT81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQKYSIEIVPKQIERLKYLPRDVFTEVYVAYIPGDKFENIVKASKSLIKDGFNVIPHCPA
RTISSKKDLDSYLSQLSSVGVKKILTLAGSGNNNFEITENPNNNFSNTLEMLETGLFEKY
QFEQINIAGHPEGNPMDPESDINLQLKCKWLHQHNFNSSIVTQWTTNLESTNKWILDTKE
MIKSKFDNNKMSITIGIAGPAKLTTLINYAKICGVNATALIIKNKKLGLRNLIRHNPAEI
IDGLRNHDSLHFFPFGGIKEVSNWFDEKVKS
>A0A3D5CL52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
LDGILERLEASDIENIIALRGDLPNNQKINLTADSGFEHASDLISHINRIYSFGIGAACY
PEGHPEAVSFDHDIHYAKLKVENGADFLITQLFYDNDDFFRFVDKARAIGIKVPIIPGVL
PVLSSNQIRKFTRLCGARIPLDLEMQLAKYENDNDGARAMGVEYATRQVQGLWDSGVSGI
HFYVLNRSYSVSKILDNLRLERSLP
>A0A536DV83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVRPLGGLSVGQALAEFLRTPRYEIFPTDDVLDLVAAHVPKEVTLAVTASPRRGLPATVQ
LAARLSQLGYRAVPHLSARLIRDRAELGQILEALKAANIQNVFVIAGDAREPAGQFPDSM
SLLEALPPDHGLTEIGVTGYPESHPFIHDDVTIQAMWDKRRLATYIVSNMSFDPATVKRW
VERVRHRGVELPIHIGMAGVADPARLLRLSTKIGVADAARFLRGHPSWLARMFRPGGYEP
GRFVSALLPELAQPDRRVGGLHVFTFNEIEPTERWRREMLTRLA
>A0A536HI86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSPSRLAGLLRDGHFVVTAELSSSNSADPQATWRRAEVLRGSVDAINCTDNTGAHVHMS
SLAAAHLLVERGLEPIMQLTVRDRNRLALQADLLGAAALGVRNLVLMSGDDVTAGDHPEA
RRIYDIDSMQLLEVAAAMRDRGTYLSGRKLEQAPSFFIGAVENPFAPPLEFRPLRLQKKV
RAGADFIQTQLVFDVPIFTRFMDMVGELELQKKVFIIPSIGIPRSARGARFMQQKVPGLH
VPESLVNRLERTAPARQAEEGIQIAVELVRAVREIPGIAGVHLIGIKWEEGVVQVAERAG
LLPRPTFSPLAAIGIVPSPARGGGQGGGVP
>A0A536KTJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGQALAGLLRTPRYEIFPTDGVVELVTAHVPKEVTLTVTASPRRGLPATVVLAARLSRLG
YRAVPHLSARLIRDRVELGQILDALKAAGIRNVFVVAGDAREPAGQFPDSMSLLAALPPD
HGLTEIGVTGYPESHPFIHDDVTIQSMWDKRRLATYIVSNLSFDPATIKRWVERVRRRGV
QLPIYIGMAGVADPARLLRLSTRIGMAESARFLRGHPSWLARMFRPGGYAPGRFVSALLP
DLAQPDRRVAGLHVFTFNEIEPTERWRQEMLARYAQEVV
>A0A2E6YIZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTNKDTNQNLNMISLRERLNVKNFVVTTEINPPKGPDTTTVLEKASMLKNYVDAINVTDS
AGANMAMAPITIAHYLTTLNINPILQITGRDRNRIAIQGELLAAHALGISNVLCMSGDSP
ADGDHPEAKGVFDLDATGILQSLEALRSGFDLSKSKLNAPADFLVGAVVNPGAKDIEKEI
TRMQQKIDLGAQFFQTQGIFDTNQFESFMEKITNFKTPILAGLILLKSAKMAQYLNDNLF
GVNVPDKIIQTMDASDNRIQTSIDISSSIIESMKPMCSGVHIMAIGWESHIPKILQNTNL
T
>A0A2D8EME0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp|TrEMBL
MSSLVTPRQAGSPSVSFEFFPPKSEAMADRLWETVERLEPMTPNFVSVTYGAGGSTRERT
HDTVRRIAQQTHLRPAGHLTCVSATKDEVLSVAEDYWDAGVRHIVALRGDPPSGMGEKFE
QHPGGFRDSIDLIEGIRAHRPDLGRCFEISVSCYPELHPESQGWDAEIAFLKAKQDAGAD
RAITQFFFEPEIYLNFLEKARAGGVTMPIVPGIMLQPNFKGLKRISKLCGASLPTWLHEL
YQGLEEDQETRELVTANVAADLCRKLSDEGVSDFHFYTLNRAGLALSTCRLLGLKPKPVE
AA
>A0A535F5P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRKALDEHYGVSTQFSTGLVKETEEKVTETANGTVSIAGLIEEEIILPRQGTPTRLQEKL
AAGEFVVSVELDPPKGLNPTKILEGAALLQQAGVNCINIADSPMARVRMGCIAMARLIQD
HLGLETIIHFTTRDRNLMALQSELLGAHALGIRNILALTGDPLRLGDYPNTTGVWDVDSI
GLIQVLRGMNEGHDAAGSSIGAQSCFHIGAALNLNMTEEETTQEIEKFRRKLEAGAHFIM
TQPIYELAPLLRFLERVGKPSIPVILGCIPLHSSRHAEFLHNEVPGIIIPEEVRARMRAA
GERGHEEGLKLAQELLSAARSMVQGVYLMPSYGRYDVVGKLTKMLLVQQTA
>A0A5D9CA81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas montanisoli|TrEMBL
MNSVPFGQLEEARRALDAPLFADVAGDATVSFEFFPPKTEKMEETLWASVQTLKILKPRF
VSVTYGAGGSTRERTHNTVARIAKETDIPAAAHLTCVEASKAEIADVANAYWDDGVRHIV
ALRGDPPVAGAKFQAHPDGYQNAADLVAGLKKLHPFEISVAAYPECHPDSESAEFDLANL
KAKFDAGADRAITQFFFSPEHYFRFCDKARAAGIDAEIVPGIMPVSNFAATQRMSAMCNT
EVPAWMGRLFEGLDDHPGARQLVAATIAAEMCRRLYAGGVRQFHFYTLNRAELSFAICHL
LGLRGDKAGLEKAA
>A0A3T0L1D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nautilia sp. PV-1|TrEMBL
MLKEKLKGKYITLETTPPKLPTVDLMIEKIEKSGALKYIDGFSTTDCPLSKLKYNSIIAA
YKLQEKFKKPVIATMTMRDRNKIALQSDLLGANDLNVINILALTGDPANMSDQPKAKAVV
EGSSILLLEIIRAFNNGMDYSGKEFKIKPKPITPFVVSNSYAKNFVSIERKMYKKIQNYA
VGIITQPVYDLNIVDKLLEIKNKIVSEFQDERKESEIVLGFFPITKLKTAQFLHSHVPGI
YVPEKWIEKLIKAHKISEEEEYKVGMELSRNLFQKLLKKHPKIHIMTANRFETVKELF
>A0A2E8R9G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLSITELIRSSSQTVYVLDVSPPRSGNDLLLQELLDLTPDVFSVAYNPGLSVRVNSVMLA
SWVQNSTGIPTSFFLATRDMNKLALQSLLLGAQLHGLNNVTVVQGDAFSETKLQYVKGVN
DFTPTEFITAIKNMNFRKDFENKNLIYPTDFCLGATVDLSKDLENEAELLHKKILLGSDY
IVFQPFFDFDLPEKLFEIFYKKFHRHVDLPIIWGIQMLENFSKSFSEIPNWVLDDLLKGR
PSIEIAQEMIEDLKNTQKVGSVYLVPPIFENGRRNYEVANELLTLIR
>A0A812RWE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiodinium microadriaticum|TrEMBL
MDQNFVDQLLTGLKAAGEPTRFRLLNLLAERELTVTEVTQILGQSQPRVSRHLKLMVEAG
LLDRFREGTWAFYRLADDGICADLARSLIGLAPVSDATLTRDRARLDEVIAGRVEVAQDY
FRQNAERWDEIRALYVPEDRVEQSISKLTGDLPHGDFLDMGTGTGQILTALAPGFDRAVG
IDLAPEMLTIARGRLDDANIANAQVRRADLFALPFDEDSFDVITAHQVLHYLDRPAAAVR
EAARVLRPGGRLIVADFAPHDLDELRDVHAHRRLGFAPEEIQSALTEAGLDAGERGFAEA
KERFAGFADPIAGDVKVSFEFFPPNTPKMEETLWESIKRLEPLDPAFVSVTYGAGGSTRE
RTHNTVIRILEETDLKPASHLTCVGAPKSEIDEIVQRYYDHGVRHIVALRGDAPADADHY
EPHPDGYHYASDLVAGIKKVASDIDISVACYPEAHPDSPDWDAEIDNLKRKVDAGADRAI
TQFFFDVEHFARFLDRVQAAGITVPIVPGIMPVLNFTQAKRFSEGAGASVPDWLGDLYAG
LEKDAETRKLVAAMVAADQCRQLNAWGVETFHFYTLNRADLTYAICHILGIRPSAEGERQ
RLLKDALKTRILSLDGGMGSLIQSYDLQEVDFRGEKFAGWNRDLKGNNDLIQVTQPDILR
EIQGNYLKAGADILETNTFSSTSIAQADYGLEDYAYEINLAGAKIARELCDQFTTENPDK
PRFLAGVLGPTNKTASISPDVNDPGFRDTSFDELRASYAEAARALIEGGADLILVETIFD
TLNAKAALFAIDEVFEEVGFTLPIMISGTITDLSGRLLSGQTAEAFWNSVRHIAPFSIGL
NCALGPNELRQYVEELSKVSDTLISAHPNAGLPNEFGGYDLGPEDMADYIREWAQDGLVN
IVGGCCGTTPDHIAAIVEARRLRLSGLEPLNVGPETGFINIGERTNVTGSAKFRKLITAG
DYDAALEVARDQVENGAQIIDVNMDEGMLDSEAAMVTFLNLIASEPDIARVPIMIDSSKW
SVIEAGLQCVQGKPVVNSISMKEGIEPFLEQARKVRRYGAAVVVMAFDEVGQAETVERKV
EICTKSYKILTEEIGFPPEDIIFDPNIFAVATGIEEHNDYAVNFFEATKIIKDTLPHCRV
SGGLSNVSFSFRGNEPVRQAMHSCFLYHGIKAGLDMAIVNAGQLTVYEDIPENLRERVED
VLLNRRDDATDRLLEIADDYRGQGAKAKVQDLSWREEAVAARLSHALVHGIADYIEEDTE
EARLQAERPLHVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKRAVAHLMPFMEAEQ
DGKQEAAGKILLATVKGDVHDIGKNIVGVVLQCNNYEVIDLGVMVPAQKILDTAKEEKVD
IIGLSGLITPSLDEMCHVAREMERLDFNIPLLIGGATTSRVHTAVKITPGYDKDVTVYVP
DASRAVGVASQLLSDTQAEPYKSEIGEEYTRIREQHQKAQSAKNRINLAQARGNAPKLDW
EGYQPPQPNKPGLHVFDDFPLEELVPTIDWSPFFQTWELAGTYPAILDDPIVGEAARPLF
KDAQAMLDKIVSEKWLTAKGVIALWPANAVGDDIEVYGDDGRNAPLATFHTLRQQMARSG
TRPHFALSDFIAPQETGLTDWLGGFAVTSGHGLKERVDAYKAANDDYNAILLEALADRLA
ESFAEKMHQMVRKDYWGYAVDETLDNEALIAEKYQGIRPAPGYPAQPDHTEKETLFRLLD
ATANAGIELTESYAMWPGAAVSGLYFSHPNSEYFGVGKVEKDQVEDYAARKGMSLSEAER
WLSPILNYDVNAK
>A0A7Z3AP03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ADAK13|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVNVPAAPHLSCVGDSKADLRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNAESYFY
FVERVQAMGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1B8UY65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. KS1|TrEMBL
MKNFREALHEQIIIGDGAMGTYLYQLGYPVGISYEILNVTDPDVIRNIHKQYVDAGAGLL
ETNTFTANREKLYRHGKEHLVKDINRAAVRLAREAAGNQAYVIGALGSIRAGKRENVHTN
QVIRDYHEQMSAMLEEGVDGIMFETFYDLEEMRLALQVVRELDQDVPVICQFAVEESRRT
KDGKSLLEAFRVLRDDGADVVGLNCHMGPNGVLRALEGVQGRIDLPLSAFPNAGLPDYVD
GRYNFVASAEYMAQSAVKFVQMGARIVGGCCGTTPEHVAAIVEALRDVEVPELPVQPVES
IIIEEESESMLWHDGAACYDGCDHGHDAEESIVDMVRSRHTVIVELDPPRDLDVSKFMKG
AQVLKEAGVDALTLADNSLAVTRMSNLALGYMALDKVGIRPLVHIACRDRNLIGTQSHMM
GLHALGIDHVLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNSGLAFSGKPLKQKAK
FVVGGAFNPNVKHLDKAIARLERKIEAGADYIMTQPVYDKELIVRIAEGTKHLNVPVFIG
IMPLASGRNAEYLHNEVPGIELSDEVRSRMNGLEGEAGRKEGVAIAKELLDVALTHFKGI
YFMTPFMFYEMTAELTQYVWEKAERQADPLYRLT
>A0A7Y3G4P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium|TrEMBL
MPLNANHRLSFEFFPPKTEAGATKLRTTRDELNKLAPDFFSVTYGAGGSTRENTRAVVLD
GLQAGCAVAPHLSFGGDSEAEIKQLIDEYAEAGVQRIVALRGDLPSGYGDGSRLVHANEL
VAFIRKHYANTFHLEVAAYPEIHPEAESYDSDIAYLKQKFDAGANSAITQYFYNADAYER
FMEGCARQGIEQAVYPGIMPITNFDNLRRFSANCGAEIPRWLCYQIEALKNDTSGYQQFC
SDFVSQLCEKLLAMGAPGLHFYTMNQAAPVTAICNNLGVTPRA
>A0A7Y3LUM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S3(2020)|TrEMBL
MSTLRDILHAGTPSFSFEFFPPKTAKGERTLWDAIRRIEPLAPTFVSVTYGAGGSSRDRT
VEVTKRIATDTTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGDPNAPWI
PHPAGFTHADELVRLVKESGEFSVGVAAFPERHPRSSDWDSEIRHFVAKCRAGADYAITQ
MFFDVEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIARFAELSGAAFPEDLAHRLDAVR
DNPADGHRIGVEYATAMAQRLLAEGAPGLHYITLNRSTATLEIHRNVTNSRSAQHALAAQ
R
>V9X334|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FGI182|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSAERFAAMEAILARSHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMNRQAAPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKTF
GWAVRQPMWATRLGAQVLHKVEHAVKHPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTALLTERLIPCIELETRHRSSWPQWFQAQTP
RQLSPQPAPRTQPES
>A0A432QHQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp|TrEMBL
MHMKNKGTKNSFSESLHDPATFTLTYELVPGRGAGGKKIDRLLEFARRAKEDGRISALSV
TDNAGGHPALAPVAIGSEIQQIGLEPLIHFSLKDKNRNQIESHLFLYQRKKFHNLLILGG
DFPKATYCGQAKPVYDLDSIQALQLIERMKAGRYRHVHGNNSHPLPFAFQCGCVVSPFKT
TEAEQVWQYAKLLKKIRAGAAFIITQVGYDLNKYEELIRFLSDQQLRIPVLANVFIPSPA
VANFMARGGVPGILLPPVLAELMQNENKEDRLLRAAAMTAALRKLGFAGIHLGGNGLDFD
DVAFVLDQAEELYKKDAIAPAGINFPMAQGWSLYRPNGGHRTRLHPGKRPGARPLHQVAH
NLLFSGTNPLSRSFAAFCRLCDRHTISRRLLTFAERVIKEILFNCRMCGDCTLPESTYLC
PQSGCPKKLVNGPCGGSSGGMCEVFPDRRCFYVRMYQRLDPNTTLEDLAGAPILPPKDWS
LEQGSSWINYFQGRDHTAKQEG
>M5E942|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malassezia sympodialis (strain ATCC 42132)|TrEMBL
MPPPYDDESDFDSDEEFSEVQLGLADGPLENEDEANPLVSRIGGRPVWLPLSPTKLPPAS
LVQCQYCQKPMQLLVQIFAPLENSAFDRNLQEREEAKKRAEAEAESRRLAQELTPAASEE
APTPIEPEDEDDDGDFDEEERLAEELAIKASLEEQRSQLQEDWTRTSSHYTTSLYLNTIP
EPRRAQDSDVPSEPPVPTKEASVGGEIEEYEQMTIDGIDDVFERFTRRLGTEARQVVRYE
YGGTPLPFSAVGSLYKQLWPSGWREPMDVSSVPPCSHCGAPRVFELQLMPNLANLLRVDK
LSDAAGILSSSNTEEHRQAEISSLLGLKDTHSDLCTGIVWSTAVVFVCSRDCCSDTEGWA
EEWVGLQHEERLHLGFSSISRLFGMIPVVREPPSIYEKIRQAPDDANLWSLEFFPPKTVL
GQANLCERIERMTKSLQPSWVHVTWGTGGSTRDSSLELAARVQNGVFDPEEDVSLVTAPR
EGACDVCLHLTCTNVDPIYLDDALDRAKRFGIRNILALRGDAPRGEEYWVATDQRFQHAI
DLIRYIRARHGDYFCIGMAGFPEGLSRGTEADQKRELAFLKEKQDAGAQFIVTQLFYDVD
LFVRWYHACRQAGITIPVIPGIMPIQNYSSFLRIVNLCGATVPQHVLDLLEPIRMDDAKV
KDMGIELSQGLIRSLRAQTDIHTFHIYTLNLEKSATNVIKGVSDVPSPIPDMPGAETWDE
FPNGRYTDARSPAFGEMDGYGASLKLPPTQAVKLWGTPVDEEDISRMFTQYVSGQLPCVP
WCDIPVWDETTQLLPMLLRLNMPKAEGGKSWWTVGSQPAVDGCDSSDPVFGFGPQGGYIF
QKAFVELFLTQEDKEALVAAIRASERPVTYFAGTCDPASMETNVQKHGLNTVTWGVFPGK
EVAQSTIIEEASFRAWRDEAFAIWREWELLFPPRSATRSLLRSIHDQRWLVTVVHHDYKD
PSGLWNLLDQVATAP
>A0A521N7Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinobacteraceae bacterium|TrEMBL
MSQAHELHFSFELFPPRTPAGWTNLPRLIGELAAVKPAFFSVTYGAGGSDQNGTYDTLMQ
VIQQTGIEAAPHLTCIGSTRAGISALLEQYRAAGVRRIVALRGDLPATSISNAAPGEFRY
ANELVSFIRETHGDRFQLEVAAYPEVHPQAANPEADFAAYVRKIKAGASGAVTQYFYNAD
AYFDFVERSEKAGLGVPVVPGLMPIVNYTQLQRFSDACGAEIPRWLRLRLESYGEDKASL
QAFGLEVVTRLAETLLKGGAPGLHFYTLNQAEPTLKLWRNLGLPTA
>A0A519FST6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax sp|TrEMBL
MKERTVSLPISLEFFPTKTPEGAVKLRAVRQTLYALKPEFCSVTFGAGGSTQDGTLQAVT
EIMSEGFPAAPHLSCIGQSRESIRERLAAYAAAGIRRLVALRGDLPSGYGSGGEFRYASD
LVAFVRAETGDRFHIEVAAYPETHPQAKSPQSDLEAFAAKVKAGANAGITQYFFNSDAYF
RYVDDLHAMGVDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRMRLQAFGDDTASIKAF
GLDVVTDLCDQLRHAGVPGLHFYTMNQSAATTELMRRLSGA
>Q6J6A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas fungivorans|TrEMBL
MSQKNAQKNFSIEFFPPKTPEGAEKLRVTRAKLAELHPRYFSVTFGAGGSTQKGTLDTVL
DIRSEGHEAAPHLSCLGSSRESLRTILAQYKDHGIKRLVALRGDLPSGYGAMDISSGEFR
YANELVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDVQRFVSKVKAGANGAITQYFYNA
DAYFRFVDEAQKLGAAVPVIAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDSDS
IRAFGLDVVTQLCERLLAGGAPGLHFYTLNQSPATIAIWQRLKL
>A0A1Y3S0S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmiger sp. An87|TrEMBL
MRLSQVFRQKECVFSIEVFPPKKNGATPESLYPTLEKLAGLSPDYISVTYGAGGGKAGLS
TVQIAKHLKQELGVEPLAHLTGINSTREQVAETVQALQDAGIENVLTLRGDICPDAPRSK
DFFHASDLATFVKSKGEFYLAGACYPEGHVESENLRQDVENLKYKLDAGVEHLVTQLFFD
NARYYRFMNLVRKAGIQAPVQAGVMPVVSARQVQRTVALSSASLPPRFTKMISRYDGDEA
ALFDAGIDYAIEQLRDLIEGGADGVHLYAMNNPEVARRVYEGIRDLLPEAKA
>A0A0P6VPS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis|TrEMBL
MISTDTPRLASTMTDAYSLEVSIKDIGALTNAAPRILPGSAMFIPYLPGQNDAARLAAAQ
MVRGLGFEPVPHLSARRIGSLEQVQAFIARLVDEADVTRCLVIAGDRSTPKGSFPDSVSL
IETGVFERAGIRTIGVAGHPEGHPIMRTADQWDVLERKCRSIQERGMAPLIVTQFGFDAD
LVVTWLEALRARGMSHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLVSRLTQAHGDIRLHLFPFGGIAQSVEWVAQYRSRTAPQDRTRAVRVDRA
>A0A220R9F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. N3-2A|TrEMBL
MSSQEHPLGISFEFFPPSTDAGREKLMHVRDELAARQPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
HFVEKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GTDVVSRLCERLLDGGAPGLHFYTLNQAAPVLKIVDNLRG
>A0A238YCF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurobacterium atlanticum|TrEMBL
MKFSEKLKNGKFIITAEVAPPRGTDPEKILKGIKPLKGYIDAFNVTDNQRSMVRASAVAM
SKILLDRGFEPICQFTARDRNKIALQSDLLGAYMLGIRNISIMTGDFTTLGDEKRAKPVF
DVDSLQMLKMVKTLQEGFLINGKELNGKPEFTVGAVFNPFAGPENLQIAKLKKKVELGAK
FIQTQPVYDIKTAKRTHEIIEETGAVPIIGLLPIKSLKMANFIRKLNPESVPAPFIEKLE
KVKDPYTYGWEYTLELAHAIAEFGKGIHFMLVGKTQELAKFIDYLKNDSPYNHKF
>G1VFG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. C561|TrEMBL
MDNNITYIKQILNDETGEKHFSFEVLPPLKGSGTASLFRNIDQLKEFNPSFINITTHHSE
FVYHEREDGLLERQSVRRRPGTVAIAAAIQQRYGIPVIPHVICSGATKEDIEYELLDLQF
LGIENLMLLRGDKAREDRFFTPTEGGHSHTTELIEQVNNFNKGIFTDGSTMKHPGKPFVY
GVACYPEKHEEAPNLEQDLRYLKEKQDLGATFAVTQLFYDNEKFYNFVDQARKMGVTIPI
IPGIKPFAKLSQLHVVPKTFHCDIPEELAGLALLCKTDEEARLLGIEWAVRQVKDLYAHG
FNNVHFYTVSAVSSVHEVMKRIVESGLLQQNSK
>A0A2V4UXT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter fozii|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPSYFSVTYGAGGSTRSRTLDIVQALCT
RGDTGVAPHMSCIGDDKSEIAELLTHYKSLGINRIVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFRIEVAAYPEMHPQARSFDSDIDNLVNKFQAGADAAITQFFYNADSYLYLR
DTLEKRGVDTVAKPLVAGIMPITNSSNLMRFADSCGADIPRYVRKQLADFGDDRKAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVEELGLTT
>A0A7K9WLX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhipidura dahli|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLRDKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMMDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7W5DIH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas fontilapidosi|TrEMBL
MNDINRAALSAGFGQRRRQATRFELLPIAGMQDAALTLPEGAVITVTCSPRHGLERTLEA
CEWLMARQFRVVPHLAARLVHDRAHLERLLDRLAALGARDAFVVGGDAERPLGKYPHGLA
LLEDMAGLTTRPERVGVPAYPEGHPRLTEGALQRDLEAKAALADYAVTQLCFEAAPLRAW
RERQQRLGLTLPVFAGIPGVMDPARLLAIALRLGLGPSVRSLRRQSGWMRRLLRPSPYQP
DGLLQGLEPVLGNAMGGFVGLHVFTFNRVAATRRWLEGHQALMPDEPAVDEAAGHPVISP
QDTLA
>A0A6N2WU19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKIRDILNKDTATISFEVFPPKKSTDFGNVEAAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGEIQKQHNVPTVAHLTCVCADRSSIGAALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKENGDFCVGGACYPEVHPDSANKNEDIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIIPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNLSEILKA
>A0A6L9UAX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium lusitanum|TrEMBL
MSSRSETCNDGIRISFEFFPPKSEEAEQQLWNTVADLSDWEPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLAAGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVAALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKAENGADRALTQF
FFDNDAFERYHDRARAAGIKIPIVPGIMPIQNLTQLKRFAGACGTSIPSWLDERFDGLDE
AVEERARVAADVAAEQIQDLMRRGIDEFHLYTMNRSALVSAVLERLGLQRKVDARAGAAA
>A0A1W9V6B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium 4572_59|TrEMBL
MKSILEKIKEQPLVFDGAMGTMLYSKGVFINRCYDELNLTSPDLVGEIHQEYRNAGADVL
ETNSFGANRIKLSEHGLGEKVREINVAAAKLARQYAGDKLYVAGSMGPCLKSGQILTDDR
KEELAGVYREQAEALKEGGVDMILLETFSHGSELLLAAQAVSITGLPVCASFTLTEEGYT
PAGESLETVISKLNESENVQMIGLNCGTGPSHLYEWVVKGIAYTKKPLIVMPNAGFPKEL
DGRMIYLSNPEYFTKYTRKFMELGVRAIGGCCGTTPDHIKIASRAVKALSVVKKHIKIKA
IIQEDENFQPVPQEEKSRLACLLKQGIKVTSVEITPPRSTDLTAFINKARICAYHGVDAI
NIPDGPRASARVSPMIAASVIQKEAGIEAVLHYTCRDRNLLGMQSDILGSVAAGLKNFLV
ITGDPPKSGDYPEVTGVFDVDSIGLTRVVHNMNYGHDFGGNPIKPPTSIFTGVGANPCAV
SPELELDRYRRKIEAGAEYSITQPVFDPMALLNFMEKASAFKEIPVIAGVWPLVSFKNAE
FMRNEVPGVEVPDSVMERMSRCQTREEGISEGIRIATEICETIEKHVQGFQVSAPFGKVE
LALKVLGKTV
>A0A7Y3K9Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacilli bacterium|TrEMBL
MGDRVALASYLQDHLLVGDGAMATQLYQLGLPVGVCYEEFNVSRPDVVRSVHRSYYEAGA
RLIETNTFSAHVLGLSRYGLEDQLEAINLAGVSIAREAVGDDAYVVATIGSLQGVRKTTI
GSFDRQSAYERQLNALLAGQPDGLLFETFLDLEELLCVVTLARTLTTIPIIAQLSLIDLG
VTRDGVPLDQAFQQLRQVGATVVGLNCRYGPADLYKAFAKTPIDPDLMLSVYPNAGLLSV
TDGDYTYASRPEYFGKMADEFRALGVRIIGGCCGTTPDHVRAMAKALEGLAPVEIVHRVM
PKAESFDHALSYAALDADEKAGSDYPTSYLHDKAKHTSTVIVELDPPKDLSVAKFLLGAK
ALRDAGADAVTLADNSLAVTRMSNLALGALMKREGIEPLLHISCRDRNLIGQQSHLMGLH
ALDIHQILVITGDPSRFGDLPGATSVFDVSSFDMIRMVKDLNQGKAFSGQTLKQKTRFSI
GAAFNPNVAQFDKAITRLEKKIATGADYIMTQPIYNPAVFAKLAKATAHLSVPIFVGIMP
LLSHRNAEFLHNEVPGITLSEDARKRMANYEGERARAEGVAIAKELIDVAVDYFHGIYLI
TPMLRYEMTVELTRYVKEKVALHRG
>A0A7X1G7S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas baltica|TrEMBL
MSQDRPLSFEFFPTKTDAGHEKLMGVARQLAAYKPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVNVPAAPHLSCVGDSKQDLRGLLDQYKAAGIKRIVALRGDLPSGMGMSSGELRHANDL
VEFIRAETGDHFHIEVAAYPEMHPQARNFEDDLVNFARKANAGASSAITQYFFNADSYFY
FVERVQKLGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQTFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLSS
>A0A2U9T6W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter maris|TrEMBL
MMPADQAQDTAMTPISFEFYPPKTDEQRSQLDRTAARLKAHAPEYVSVTFGAGGSTLSHT
PEAIQRLAGEHGYSAAPHITCMGGSRQEIRGLLKLYKAMGARRLVTLRGDLPSGMVSPGD
LRYANELVEFIRAETGDHFHIEVAAYPEMHPQARDAHADLGHFKRKVEAGADGAITQYFY
NADAYFRFVDDARAAGIDIPIVPGIMPISNFSQIRRFSDMCGAEIPRWIAQRMLAYGDDA
ASVRAFGADVVAQLCQRLIDGGAPSLHFYTLNLAKPTQSVIDRLA
>Q7VUM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)|TrEMBL
MTQSTAPAFSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRT
LRNLGCDAAPHLSCIGATRDQLRDILAAYREQGVRRLVALRGDLPSGMGGDAGELRYASD
LVAFIRQETGDWFHIEVAAYPEMHPQAESPSADLAHFVNKVQAGADAAITQYFFNPDAYF
DFVERAQAKGVAIPIVPGIMPITNHTQLVRFSEMCGAEIPRWIRLRLAEYGDDKASIRAF
GLDVVSELCQTLLENGAPGVHFYTLNHAEATLGIWKALNA
>A0A3E0UJ39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassotalea euphylliae|TrEMBL
MTYSHARQVESLNQSLSEISSDINVSFEFFPPNSPAMETTLWNSIERLAPLKPSFVSVTY
GAGSGTRDRTHDVIKRIQKETALLAAPHLTCIDAGREELVQIAKDYWDSGVRHIVALRGD
LPDSSEKKPSMYAADLVELLKSVADFDISVAAYPEGHPEAPNPQFDLLNLKRKVDAGASR
AISQFFFDIESYLRFRDRCVSVGIDVEIIPGILPVTNYNTLKRFAGLTNVHVPSWMPKMY
EGLEGDETTRRLVGANIAMEQVKVLQKEGVKDFHFYTLNRAELTYAICHTLGIRPK
>A0A256WDQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium 4572_114|TrEMBL
MKVIELLKNTDKTLFSFELLPPLRGGNIESVYKVIDPLIGFNPININITYHQQEVVYKKL
PSGLLQKKTVRKRPGTVAISAAIKYRYPQLEVVPHLICGGFTKSETEYALIDLHFLGIEN
LLVLRGDPPKSQRLFQPDPEGHQFAIDLIEQITNLNKGIYQDDELRNKTATDFSVGVAGY
PEKHFEAANMDADLQYLKEKVDSGADYIITQMFFDNKVFFDFVERCRNFGIEVPIIPGLK
PISSMNDLRLLPLVFHIDIPEGLAAGLRKCKTNEAAIQLGIKWSVKQSLELKDYGVPALH
YFTIGVTDNIRQIAGKVF
>A0A1Q6F697|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes putredinis|TrEMBL
MNITDLIQGTVASRTTRFAFELLPPLKGDGTRSVFGAIDPLMDFNPAYINVTFHREALKE
DVRPDGSREWHIMRRRPGTVGISAAIRRKYDVEVVPHLICGGWSKYDIEDSLIDMDFLGL
HNVLALRGDKRQNEPRFVPYAQGHAHAADLVRQIQAMNRGEFIDGEVEECHHSKFSVGVA
GYPEKHFEAANAQSDLQYLKEKVDAGADYIVTQMFFDNSKYFDFVERCRKAGITVPIIPG
IKPISTPKHLEILPRTFSVSLPEELVKAVRACGEDTQAAREVGIEWAIHQAKELKAAGVP
IIHFYTMGRTDNIRKIACNVF
>A0A443JAC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium enclense|TrEMBL
MTVLPLLDVCPKRMEYGPCGGVGFDGSCEIDAEHSCAFLPRGTVRWTGIDRVSVPDPGAR
TAAAAETLASLGTRPWVVADLPARAMSVASIDSCGAILVGEVDAVLAGDAGTARVQFPPA
YRAHLLQRAGLRVWTGLNMRDRNRVAIEGELAALAVEGVAGVHCVTGDHTRTGNRPDAAP
VFDLDSTEAAALARAAGHVVSVAASPAAPPVERRAARLREKLRAGADVCFVNHAGGAEPV
RRFIDSVAAPVRYIPCVPVVIDHASADVLESFTTLVLPDGFLSRVRGARDPRAEGIALAV
SLAEELLALPGVVGVNLSGGRDGGEESFAEAQAEIARRLR
>A0A1H5YR39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopseudomonas aestusnigri|TrEMBL
MTTNAPISFEFFPTKTEAGHEKLLATARTLAAAGPEFFSVTYGAGGSTRDGTRRTVLQLD
GEVKVPTAPHLSCVGDSRDDLRSLINDYRANGIQRIVALRGDLPSGMGHASGELRYANEL
VEFIRAETGDHFTIEVAAYPESHPQAPNFETDLQNFIRKARAGADSAITQYFFNADCYFH
FVDRVRQAGIDIPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDSISAFG
TEVISQLCERLLDGGAPGLHFYTLNQAEPSLAVVRNLQGDR
>A0A2S9XBA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enhygromyxa salina|TrEMBL
MLIRDRLAHKRPVFSFEFFPPKNAKGERVLWRSLEQLAPLEPDFVSVTYGAGGSTRTRTV
ELVGRIKRELGVEPLAHLTCAGSTRDELEAVVERLLEQGIRNILALRGDPPRGQETFEHT
PGGFRYASELTAWLRDRWPELCVGGACYPEVHPEAPSGEADLRNLQAKVDAGAEFLISQL
FFDNAAYFEFTDRARGAGIEVPIIPGIMPVTNVKQIERFTKMCGATIPKVLHQRLHAIAD
TKDGYDPQEVFWTGVSYAAHQCRELLDRPPGGPFRRQASTVAGVHFYTLNRSPATRALFE
ILELARPVR
>A0A066U6I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis rifamycinica|TrEMBL
MTSVIERLRGDGPKFSIEFFPPRDTADEAVLWKAVRELEPYDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYASVGVRNILALRGDPPGDVYGEWI
PHPEGLQYAEELVQLVRSLGDFCVGVSASTYGHPRSPDLESDTKYLVRKLRAGADFAIAQ
LFHDAEDFLRLRDRVAATGCDVPVLPGVMPLTTMRTLQTTIKLSGAPAPRKLLDRLEPLA
DDPKAFRAAGIDVITELCEKLIAEGVPNLHFYTFNRSKATREVIARLGLVPARA
>H3NC00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dolosigranulum pigrum ATCC 51524|TrEMBL
MTIIDKYQQKQVFSFEMFPPKGKHNMEKLHETIDLFSTLKPDFISVTMGAGGVGNSKGTV
DITDDIQQRYQIDSVVHLPSIHLSKPEVSDILADLKRRNISNILALRGDEHPGTSRSQDF
NYASDLIEFIKESGDFNILAACYPEGHTQSASIVEDVKHLKRKADAGVDAFVTQLFLDNE
YFYRFRERADIVGIDQPISAGIMPVTSKKQIERMIQLTGANLPKKFVSIIDRFGDNPKAL
LDAGIAYAVDQIIDLLAQDVNGIHLYTMNNSYIAKNIYRAIKNIV
>A0A2T5HBN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas oligotropha|TrEMBL
MESQKNFPPAFSFELFPPQTPEGVEKLRLTRQQLARFNPKFFSVTFGAGGSTRERTLETV
LEIQTEGYVVAPHLSCIGSTHQNIRAILEKYYEAGIRHIVALRGDLPSGMAQAGEFRYAS
ELVAFIRQEYGSSFHIEVAAYPEYHPQARSAQADFDNFKRKIEMGASSAITQYFYNADAY
FHFVELCEAAGLNIPVVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKLEGYGDDSESIQA
FGLDVVTGLCEQLLQAGAPGLHFYTLNSANLTSVIWQRLNLHAR
>A0A6J7FPC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSDYLKTTTFSLEFFPPKDSIGEERLWQALSQLQPLKPDFVSVTYGAGGSTRDRTIRVTT
EITDRTSIPTVAHLTCVGSTKTELVEILNQYKSAGIKSIMALRGDPAGGPRAEWQNIEDG
FDHADQLVQLAASLGDFKIGVGAFPDGHPASGFNFDKDVDVLIRKEELGATFATTQFFFE
SSKWHKLVERLLKRGSKLPIIAGILPITNLKQLDRMVELSGTPIPAAVSKRFENSLNSPE
DIKKIGVEIATELGNELISLNAPGLHFYTMNSASSTISIAKNLGLVR
>A0A7Y0CBT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax sp|TrEMBL
MTMTTATPLSIEFFPPKTSEGVEKLRLVRQQLYALKPEFCSVTFGAGGSTQEGTFNTVRD
ILAEGVSAASHFSCIGATRATVRAQLATLKAMGVKRLVALRGDLPSGYGAGGEFQYASDL
VTFIRAETSDDFHLEVAAYPEVHPQAKSPASDLQAFAAKVKAGANSAITQYFYNADAYFR
FVEEVDAMGLTIPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDDLPSIKAFG
LDVVTDLCAQLQAGGAPGLHFYSMNQSVATLEICKRLGC
>A0A6J7U148|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MKSGGTKALTYSFEFFPPKDVEGEERLWAAMSQLESIAPDFISVTYGAGGSTRDRTIRIT
SEITARTHIPTVAHLTCVGSTRNELVDILSKYRDAGIKSILALRGDPTGGPRAPWSATEG
GLNHADELVTLAAEFGGFTIGVAAFPDGHPSSDGDINKDVQVLLEKEKRGATFATTQFFF
EVDKWKSLVDKLAAKGSSLPIIPGILPVTNVKQLNRMAELSGTPIPAHISESFAKIEDDA
DAVRALGVEIATKLCQDLLEAGAPGLHFYTMNTSSATREIYSQIKDER
>A0A7X8S8X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. ERN07|TrEMBL
MATPQIHPNWDKVPNGITDGFSLEMTAKDEASLRDAAPLIPAETPIAITFLPGEDVAARV
AATVAVRELGFEPMPHFSARRITSEDDFEGYLRAVVEQAGVERCFIVAGDPPEPVGPYFD
TSALIATGAFERSGIKAIGIGGHPEGHPNMTEAECWAVLEKKVADITARGMAPLIVTQFG
FDPDAFLNWLKELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVTN
LLGTAGPDKLVDAFARGLGAEHGKVRLHFYPFGGLTKTLEWLQGYNKKHGINQ
>A0A6J7K865|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRKEGSFVGGPVSAAPGPSLGEVLASGERSFSFELFPPKTDDGERALWQTIRDLEALNPT
LISVTYGAGGSTRDRTVRIVAGIAAEPALTPLAHLTCVGASRDEVRSVIDEFAAAGVRAI
LALRGDPPGGPGAPWAQHPDGFAHADELVELIASMGGFSVGVAAFPEGHPESPDLDADAL
VLARKQDAGAEFAITQFFFEARDYERLVSDARRHGCTMPILPGLLPVTNVAQIERFAALS
GAAFPAELAARFALVKDDPDAVHALGVEVAAALAQELLDLGAPGLHFYTLNRSTSTREVY
EALGLGSD
>A0A6J6K713|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MYSFEFFPPKDLAGEDRLWQALETLALHAPDFVAVTYGAGGGTRDRTIRITSEITARTKI
PTVAHLTCVGSTRVELIEILDRYKDAGIKSILALRGDPVGGPRAPWTAVDGGLTHADELI
TLAREHSDFTIGVAAFPDGHPNSGGDMNKDIDVLIRKQSLGASFATTQFFFDVDKWKRLV
DTLESRGCDLPIIAGVLPVTNVKLLTKMAELGGTPIPDSIASRFAAVEDNPDDVRKLGVE
IALDLCNELIDAGVPGIHFYTMNSSTATSEIFTSLQERR
>A0A6G7CB94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. Sr18|TrEMBL
MKVTQHIEAAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKLGGNDFAVDLVKQINQLNCGKYLHDVMDVDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVSKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIKQIASKIF
>A0A7Y5J141|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospiraceae bacterium|TrEMBL
MKVTEYFEKAAGQTLISFEVLPPLKGGRMQAIFDTLDPLMEFKPPFIDVTYHREEFVYKK
RTSGYYEKTAIRKRPGTVGICAAIMHRYGVDAVPHLICGGFTKEDTENALIDLNFLNIKN
VLAIRGDARKFEGHFVPEEGGHHYALDLVKQIADMNHGRYLDDNIENGDRTDFCIGIAGY
PEKHFEAPNLDLDLTYTLQKVAAGAQYIVTQMFFDNAKYFDYVKKCREAGITTPIVPGLK
PITKQYQLSSIPRLFYIDLPEDLVKSVLAAKGPEQIKQVGIEWCIQQSKELKAAGVPCLH
YYTMGDVETIRKIAESVY
>A0A7Y8M504|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MKPEISCEFFPPQTTEGLEKLRATRERLAAVAPSFFSVTYGAGGSTRERTFDIVMEIAAE
GIAACPHLSCIGSTRENIRKILADYRAHGIRRIVALRGDLPSGMADVGEFRYANELVAFI
RQETGDWFHIEVAAYPEWHPQAKSPRDDLMNFKRKVEAGANSAITQFFYNADAYAHFVAE
ARALGITIPIVPGIMPIGSFAKLARFADASGAEIPRWMRKKFESFGDDTDSIRAFGLDMV
TELCERLLALGAPGLHFYTLNQAGLTLEILRRLGLAG
>A0A6J6NPT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MAKNSQRNGTLLTMGTKLRATSFSLEFFPPKDEAGEQRLWLALSELAPLAPDFVSVTYGA
GGSTRDRTIRVTSEITKRTQIPTVAHLTCVGSSKDELIQILNQFKNSGIKSILALRGDPV
GGPTAPWEPTPGGLNYAQELVEIAVEMGFKVGVGAYPDGHPASNHDLAKDITVLLAKERA
GASFATTQFFFEIDKWQAIVDKLAATNSSLPVIAGILPITNVKQLNRMVQLSGMQVPDDI
AEKFAKVADDADATRKLGVELATNLGAELLRRGAPGIHFYTMNSAQSTIEIAQNLGLIKN
D
>A0A7V5EM85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospiraceae bacterium|TrEMBL
MKVTEYYEKANGQTLVSFEILPPLKGGTIHQIFDALDPLMEFKPPFVDVTYHREEFIYKS
MPSGHFEKVAIRKRPGTIGICSAISMRYGVDAVPHLLCGGFTKEETENALIDLNFLNINN
VLALRGDARAFEGKFVPEENGHEYAIDLVKQIVDMNHGKYMDEHVINGANTDFCIGVAGY
PEKHFESPNMEADIINLKRKVDAGANYIVTQLFFDNKNFFEFVKKCRAAGIQVPIVPGLK
PVTKKYQLNSIPRKFYVNFPEDLVKALLAAKDATARTRVGIEWAVMQSKELKAAGVPGIH
YYTMGDSAIIQQIVEQVF
>A0A7I6Q130|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. WP2-W18-CRE-05|TrEMBL
MGFHSARQVEALNQSLADLGGDISVSFEFFPPNSEGMENTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLENDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQA
>A0A2T3AEW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coniella lustricola|TrEMBL
MDKITDKIAALPPNADYFSLEFFPPKTSMGFANLRSRLERMARALKPAFVNVTWGAGGST
EDKSLELAEICQRELGLTTCLHLTCTNMGRWQIDKALDDAKALGIRNILALRGDPPRRDE
YKDDNKEADLDGSEEFNWAVDLVRYIRRNHGDYFCIGVAGYPEGHADESHPQGQSLEHDL
PSLVEKVQAGADFIMTQLFFDIDAYDTFERTLHEHPSGAFKDIIIIPGLMPIQNYQMIKR
TTKLSHARIPDNIMARLDEVKKDDEKVKQVGVDILSELVEQVREIKSRTPGPRGFHFYTL
NLEKAVSFILERTNLIPSDSDADDEAVLDDLLPAIPRIALNGTGSNRSQEAGRERSSRRL
SHVSSEPRNRVIISGERTPSNPEYEATQLEASRPYEPVQSRANTLAISEGEGVLGREATW
DDFPNGRWGDARSPAYGEIDGYGVSLHMSVTQAKSLWGQPTTAADISNLFIRHLKGELRA
IPWSEEEFNAETATIRDQLLAVNSRGWWTVASQPAVNGLRSTDATYGWGPANGFVFQKAF
VECFMPKNDWARLHARLTEPEMKDRVWFYAANAEGDFVSCDGSGGLDREVKEAGTNAVTW
GVFPGKEIITPTIIEEVSFRAWAEEAFGIWGEWAQVYGKGSDSWKLLEQLKGELWLVNII
HHEYIDKDALWDFLMSA
>A0A3N5QI75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriales bacterium|TrEMBL
EHLTKAKEPLISFELIPPKRGGDFFSLLSVIDDISKYHPPFIDITSHSAEVIYEETSKGI
KKIIKRKRPGTLGICALIQNKYNIDAVPHILTNGFTREETEDFLIELNYLGIENVLAIRG
DDMGYEKPLPEGRSRNLFASDLVKQIVNMNGGKYLEDSLLDARPTNFCVGVSGYPEKHFE
SPNLLTDIKFVKQKVDAGAEYVVTQMFYDNEVFFKYVDLCRKEGINVPIVPGLKILTSKA
HLVNIPKNFYVNVPQDLVDEVTAAKPEQVMDIGVEWAVKQVEGLLNKNVPSVHFYIMQNS
LPVKKLMERLKLFRKIA
>A0A3A1WQM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas flava|TrEMBL
MIQRRDTRPRIEVSFEFFPPKTPAMEDSLWAAIQRLAPLRPSFVSVTYGAGGSTRERTHH
TVERILQETDLDPAAHLTCVDASRAEVDDVVRQYRATGVRHFVALRGDGQGGAGSAYVPH
AEGYRNGAELTAGIKAIDPEIEISVSAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNDLYERYVERARRAGIYVPIVPGIVPIHDFSKVARFSAATGTSIPLWLAERFEGLEN
DAQTRSHVAAAVCAEQVLDLVDRGVSDFHFYTMNRADLVYSICHILGLRENAPVREEAAA
>A0A0Q5TNF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter sp. Leaf189|TrEMBL
MTKVTDFIQQANGKTLFSIEIIPPLKGQNINELLNSIEPLMEFKPPFVDVTYHREELIDR
VRTDGTIERIPIRKRPGTVGICARLMERFHVDAVPHVICGGFTKDETEDVLIDLHYLGID
NVLVLRGDPEKSAGVFQPKTGGHTYASELVAQVHNMNNGILLNAETEMSPTNFCIGVAGY
PEMHFDAASIDADYEHLRKKVALGADYIVTQMFFDNEKYFRFVERCRAEGITVPIIPGLK
PLATRKQLSVLAQIFHLEFPQDLVKEVEKCATDKEVRQVGIEWGIQQCKELMAYGVPVLH
FYTMGKSDNVAQIARQVF
>A0A257NEW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium NSO1|TrEMBL
IQAKGIAAAPHLSCVASTKDNIRAILKDYQDNGIAKIVALRGDLPSGMMSAGEFRYANEL
VEFIRQETGDYFQIHVAAYPEVHPQSTNAMEDFKNFKRKVEAGANAAITQYFYNAEAYFY
FVDTCEQNGITIPIVPGIMPITQYAQLFRFSEMCGADIPRWMRKRLESYGDNREAVQSFG
LDLVSNLCQRLLDGGAPGLHFYTMNQAAPTLAILENLQIK
>A0A431MK08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MSLDFELSIEFFPPQTAEGMDKLRAARDKLAVLNPTFFSVTYGAGGSTQERTFEAVFDTQ
TAGIAGGYEAAPHLSCVGSSRDSIRAILQRYQERGIRRIVALRGDLPSGTGDPGELRYAN
ELVAFIRAETGDHFHIEVAAYPEWHPQARSPREDLLAFKRKVDAGADSAITQYFFNADAY
EHFTDECQALGITTPIVPGIMPIASFSKLARFSDACGAEIPRWMRKKFEGFGDDTDSVKA
FGLDVVTELCERLLKAGAPGLHFYSMNQAELTAEIVRRLRA
>A0A1T4XHX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecobacter debontii|TrEMBL
MHIADILAAQRPTLSFEFFPAKTAEASEALFETITDLESFKPSFVSVTYGAGGSTRELTH
DLVVRIKKETTLDPVPHLTCVCHSEADIAAILERYAEAGVSNILALGGDPPRNLEGYNRK
NDAFQHAADLVSFITKFNNSHSHPDRRGFGIGVAGFPEGHPSTPNRMLEMDYLKAKVDAG
ADYICTQLFFDNHDFLDFRDRCRIAGIHVPIIAGIMPITSAGGMRRMAELAAGARYPAKL
MRAIQRCNGDEEAVQRVGVHYATEQCRDLLEHGVDGIHFYTLNKSQATREIYASLGIRDS
IAVRNS
>A0A212Q3T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. es.042|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYREHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEMVTEMCEKLLAAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A2A9GYX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriaceae bacterium ES.041|TrEMBL
MSRRDPSIAELLAASDRPLFSFEFFPPASEEAARTLWQTVRQLEPLGPDFVSVTYGANGS
TRDRTINVTRQIARETTLRTMGHLTCVSQSRDDIRRVVGAYADAGIRHILAVRGDPPGGP
TAPWQAHPDGLRNATELVELVASLGDFCVGVAAFPDVHPEHHDPELDARILVDKANAGAD
FAITQLFFTARSYFELVDRVRSLGCDIPIIPGIMPVTNLRQIERFAELSGAALPTGVTDR
LLAADGPDAVRAEGVRIGTELADELLAGGVPGLHFFTQNRSRASREIHSRLQRVPA
>G5STE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraprevotella clara YIT 11840|TrEMBL
MNVIDLIQNHKGTAFSFEVLPPLKGAGIDRLFHTIDTLREFNPAYINITNHRSEYVYKDL
GGGIMQRLRIRRRPGTIAVAAAIQRHYDIHVVPHILCSGYTREDTEYMLLDLQFLGISDL
LVLRGDKAKEDPAFRPTGDGYSHATELIEHINRFNEGFFVDGSPIKSPGTSFSYGVACYP
EKHEEAPNPEADLAVLKQKADMGAAYAVTQLFYDNAKYFDFVDRARRAGITIPIIPGIKP
FAKLSQLNVVPKTFHCDLPQALALEIGKCKTDEEAKQVGIEWTVEQCRELIGHGVPSIHF
YTVSAVDSIREIARQIY
>A0A3N0GTZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmoricola pocheonensis|TrEMBL
MGTGSTSSIAALLARGERSFSFEFFPPKDAAGEEILWRSISELEELRPTFVSVTYGAGGS
TRDRTIEITGRIARETSMTPMAHLTCVGHTVEEIDQILDSLAAAGVRNVLALRGDPVGGP
GTPWVPTPGGVDYAADLVALVRRREQFAVGVAVFPEGHRDCADLEQDVRVMRAKYDAGAE
FAITEMVLRASDYLALVERSRAAGIDIPIIPGIMPILNLNSMRKMVELSGREMPAEVLRR
IEPLADDPEAVRAEGIRIATELCDELLAGGAPGLHFYTLNRSKATREIYTSLACHA
>A0A2T2RL30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium QS_5_72_10|TrEMBL
MVRIADEISRGRTLSFEFFPPKTEKGLANLRQAVNDLAKREPTFVSVTYGAGGSTREKTE
EIVTEINRNTGVTPMPHLTCIAHARHELEAIVRRYRREGIENVLALHGDLPKDNPDIESG
DLARAAQLVELIRGAGDFSVGVAAHPEGHPKAPDPETDRRHQAEKLKVADFGVTQFFFRA
EDYLRFVDEMDTHGVDTPIIAGVIPVTDAKQTARFAEMAGADFPADLAERFEAAGDDADE
VRRIGVDVATDVCQRVLEAGAPGLHLYALNRSQAVGELCDNLGFGAWAPAGKL
>A0A1B8D9P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. 24MN13|TrEMBL
MADSPTTDKITDKIAALRQDASYFSLEFFPPKTAMGSTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSKALVDDALKAAKEAGIQNILALRGD
EPRGEYKDALEEGKEGEDEFVWAIDLVKYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
EHDLPYLVDKVQAGADFIMTQLFYDVDAYDNFEKVLRDHSSGAFKSIPIIPGLMPIQSYQ
ILRRTTKLSNAKLPESIIDRLDAVRTDDEMVKKVGVDILAEIVESVKATKQRTKGPKGFH
FYTLNLEKAVAFILERVNLIPSFTPVLTSDAVAVDDITDTIPLPQLLINGQKKNRRQSSV
GSGPHNFVIIDREEASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRPDITSIFVQYLNGTLSALPWSDE
PIAAEANLIKDELVKLNQKGWWTIASQPAVNGARSQDEVVGWGPKGGWVFQKAFVELFVP
TSDWARLKPLLEGNGEVSFLAQSASGEFLKSKLDLGPGEEGSETNAVTWGVFPGKEIVSP
TIVEEVSFRAWAAEAWPTEEEWAAVFGKSGEESRRFLDGVAKDGWLVNVIWHDFVGMCKA
KEGRSEEEGYKGLWDVLIEA
>A0A3M6E1R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. atropurpurea|TrEMBL
MFTSRRYGLKMSVLKKALLDGVFTCVVEYVPKPSSERFTAFEALMEQSRLHEWPLVPAVA
DRVGGKFDIAPVDACAALKGPTPALIHFSGKDRERSDLLSELDRMDRLGVNQLLLISGDR
LPGHQPGQHPVRYLESVPALQIARAARQDWLLGAALNPFKYREEEGCAQYLKAHKKLAAG
ADFLTLQLGFDAKKHIEAVAWMTSQKTPKPLLACVMGLTEKRASLLKSVPGIVVSPSMLG
VLAAEAAVSKEHARSRCTDRLALQIVGLRLMGYAGIHLSGIHTVQELEALEQRISVWVKN
IGSLEHWSAAWADSWQPPGQLAVTFNPPGASWYLGESSVKATPKETLRYHVLAGFHSSLF
SHTTLLGGALGWAVRRPVWSSARGASLLRQLERSLKRPLVGCDTCGQCRLEDTLYICPET
CPKGLSNGPCGGTYLNRCEFGDRECIHSVKYRTAKSVRRIQVLTDRLIPCVEQGSRHSSS
WPRWFEADASQTRGTSD
>A0A7U7FI23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia enterocolitica (type O:5,27) str. YE149/02|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A8J6NV35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfatibia profunda|TrEMBL
MKVKTPSKLEKILAAGHHAVTSECGPPRGSDMQVITEKAEMIKNHVDAINITDNQTSVTR
MCSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAAAFDIHNILCLSGDHQSFGDCA
QGQNVHDIDSMQLAQTVRLMRDEGKFLGGGDIGRPPKMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNMEKFELWLKMAGDRGLLEKVYILAGVTPFKSAGMAKYMKNRVPG
IEVPDELVKRMAGTPKEKQPEEGIKICIEQIQHLKEVEGVHGFHVMAIEWEEMVPEIVEK
SGLYPRPSVD
>A0A7J7A5R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lamprigera yunnana|TrEMBL
MGLLFAKLWSLFGNEEHKIVIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEVVWRNI
HFIMWDLGGQQSLRAAWSTYYTNTEFVIVVIDSTDKERLITIREELHKMLSHEELSKAGV
LIYANKQDIKGSMTATEISRQLDLTSIKKQQWHIQSCCALTAVMEEESVFNKARILNIKI
LSMEVLLKNLDLVELDKASKTLFSLAWVSGERNLATFLDIYKNPLKGLSDCYKHILFNLP
CCNLSEGDANVILTILKLLNVRYILALQGDTSSRIESEFKYAIDLVKYINKDFNGWFKVG
VAAYPQGHPASLNFEEDLIFLKNKVHAGADFVITQMVFDYDIFNHFYKAFKIICPDTPVL
VGVFILAKYEYYEVAKKLVGRELPSFVTEVVTKNKKNPTAILNFGIHLAATFIKDVLRNC
DSQISGIHFFSFNNFELVRSVCKLAGLSEVHVERPLNSSSCSYFILKDTDEASSSIE
>A0A7X5QY89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacter cavernae|TrEMBL
MSAGGCSSSITVGGEGSAATATGGQPQRVPFSYEVFPARSSAAALALGHTVQHLAASGPE
FISVTYGANGSSRDASLDLLKYIKQHTEARPLAHLTSIGSSKAEIEQLVADFWQAGVYDF
LALRGDPPRGVSEADVELGEVPNTVEFVDLIQSILKRQSGATGRVCIAAFPNKHPRSETI
NDDINVLLAKQDAGAAFAITQLFFHADDYLRFVDAASRAGVRIPILPGLMPVSTSAQLLK
VAELAGEQAPDDLLARLEAAGGYGPECGVEHTVGLASRLVSEGAPGIHLYTFNRHQSVLA
VLRELGLLTNHPFEKELA
>A0A7U0NA48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia proteamaculans|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGGGKPEMYATDLVTLLKDVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAVA
>A0A2C8X481|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. OK228|TrEMBL
MLGTGKATYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSVTYGAGGSTRAGTVKETEQ
IVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVPHPQGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDGDVAHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVVAAGCTTPVIPEVMPVTSVKMLERLPKLSNASFPDVLKERILTAKDDPAAV
RSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGLHHPQQA
>A0A529N872|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDT
>A0A0C1GX05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morococcus cerebrosus|TrEMBL
MSYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHSIVKRIQQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A442WYR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETAIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A529KUS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
CFDVPMFKAFMQSARDLGHTEKVFILCGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEG
AQDQKKEGKQLCIDIINEVKEIPGVAGVHVMAYRQEEYV
>A0A6B2SAD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID10853|TrEMBL
MTYTAAPTFSFEFFPPKTAKGEQTLWSAVRRIEPLAPDFVSVTYGAGGSSRDRTIEVTKR
LVSQTTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPSAPKGPWRPHPDGF
TYACQLVELVRSLGDFTVGVAAFPEKHPRSPDWDSDIRHFVAKCRAGADYAITQMFFDVE
DYLRLRDRVAAAGCDVPVIPEIMPATDVRQIRRFAELSDAAFPEALAHRLEAARERPDDA
YRIGVEYATAMADRLLGEGAPGLHYITLNKSMAALDIHRNVLSSRSLHVS
>D9XEY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces viridochromogenes (strain DSM 40736 / JCM 4977 / BCRC 1201 / Tue 494)|TrEMBL
MTTFSFEFFPPKTDNGTRALWDTIRRVEALRPDFVSVTYGAGGSSRERTVDVTRRIASET
TLRPVAHLTAVGHSTAELRRIIGQYADAGIRDVLALRGDPPGNPNAPWIPHPQGLTYAAE
LVELVRSLGDFTIGVAAFPERHPRSPDWDSEIRHFVAKCRSGADYAITQMFFDVEDYLRL
RDRVTAAGCDTPIVPEIMPATDVRQIRRFAELSGAAFPEHLAHRLEAARDRPADSHAIGV
EHATAMARRLLAEGAPGLHYITLNKSTATLEVHRNVLGSAADSAANARSTRVLVHD
>A0A529X5A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWQREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A353WIV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium UBA9579|TrEMBL
MKLKEIYNSKKPVISYEIFPPKGEFPEIEPKIDALFQELKVLSKYNPSFISVTYGAGGST
REKTLELVLKVKNELNIQPLPHFTCVGTEIDQTLEYIKQVQNAGIENILALRGDPPKGET
KFVKPKNGFGYANELVEFIKSHTDLGIAVAGYPEGHQECVSFEQDIVNLKKKVDAGSDVI
ITQLFYDNNYFLNYLDKTQKAGINIPIVPGVMIITNVAQIERMISMCGCTIPDKLMAKLK
EYQDDNKAVREIGIEYAINQCKELLENGVPGLHFCTLNKSFATDSVLKELV
>A0A5R9J5T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lichenicoccus roseus|TrEMBL
MNEASPISGPISGLAPLERWLTGPRVAGLPMRDFASPAPILSFEFFPPRTEALESQLWAC
IRRLETMRPSFVSVTYGAGGSTQARTHDTVARIVRETSLTPAAHLTCVGASRGAVDDVAR
QYWDAGVRHIVALRGDPPKDSAFEAHPGGYASAAELVAGLKRVADFEISVAAYPEKHPEA
TSVQADLDNLKRKLDAGATRAITQVFFEADTYLRFLDRCLATGITEPVVPGIMPVSNFGA
AVRFAASCGTTVPDWLAAMFGGTEEDADTRRMVGAVVAAEQVRLLQANGVDEFHFYTLNR
PDLTYAIAHVLGVRPQAARPADDAAAAAG
>A0A526RRB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MTIRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAXXXAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVF
ILCGVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPG
VAGVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVD
MVKTAH
>A0A529CMS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRISIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRAYMQKVRDLGYTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDQIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRRPWKREIRRDDQLVADRLDHILHDDLTETQVDMVK
TAH
>A0A8J3KWP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catellatospora coxensis|TrEMBL
MADDTAPARRSLRAMLERAEAGVLLLGITPPRSSVSAEQAAQIAEVTLARLATVDLDGLI
LYDIDDESDRNPQERPFPYLPTMDPVSFHRDHLGGWERPAVIYRCVGKYTEPELADWLGE
VDTDRVLSVFVGASSRDKGVRTGLTQAYTLRDRVRADLPLGAVAITERYTRSGDEHLRML
TKQDRGASFFITQVVYDVDATKSMLSDYFYTCAAKGVAPRPVIFTLSVCGSLKTLSFLHW
LGVDVPRWLENALRFSEDPLTESYQQCIATARELSAFCRRLGVPFGFNVESVSIRKVEIE
ASVELAREVRELLNS
>A0A1C7NT58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Choanephora cucurbitarum|TrEMBL
MKIVDKIEQAQKSQKIAYSFEYFPPKTDLGFANLIDRLGRMSQLEPEFISCTWGAGGSTS
VRTLELCSTAQNLYGLDTLMHLTCTNMEREKLDAALQQAKEAGIHNILALRGDPPRGHEY
WTPVDNEFKHAIDLVKYIRQQYGDTFCIGVAGYPEGHIDCADLDQDIQYLKEKVDAGADF
IVTQLFYNTQAFIDWMDKCRKAGIHAPIVPGIMPIPTYQSFRRMMHLCNLKVPARILNDL
DLIKNDDQKVKEYGVRLAVDMIKQLHDEGSICNFHISTLNLERSTRLILEALHLHKQETL
STSKIPPWAPVHDPARAELWDEFPNGRYGDSRSPAYGENTYGAGQILPTSGASCKWGQPV
HEKDITQLFVKYIQGELDSLPWCEERLQTESDAIRQRLSDINQRGYWTVSSQPAVNGVSS
EDQVYGWGPKGGYVYQKAFIEFFVSDTQIKELLSRLSKDSSITYYATNLKGDFATNVIDA
EAQNAVTWGVFPGKEIIQPTIIEKASFEAWKEEAFGLWKEWEEQYPPKSSSQKLLENIRE
KYWLVNVVHHDFQKSNLLFEAMLSK
>A0A809PQM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Undibacterium sp. YM2|TrEMBL
MKTPNFSIEFFPPKTAEGTEKLRVTRAKLAELNPKYFSVTFGAGGTTQQGTLDTVTEIRR
EGHDAAPHLSCVGGTRESIRAILNEFKANDIRRLVALRGDLPSGYGMGGEFRYANELVEF
IRAETGDWFHIEVAAYPEMHPQARSPQDDLNSFVRKMNAGANAAITQYFYNADAYFRFVE
EARKAGVTAPIVAGIMPITNSTQLQRFSEMCGAEIPRWIRLKLASYGDDTASIKAFGLDV
VTTMCERLLAGGAPGLHFYSLNQAAATTAIWQRLV
>A0A5C1QRS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanispirochaeta crateris|TrEMBL
MLTPFLERIKKQPLVFDGAMGTMLYTKGVFLNRCYDELNLTNPEIVGEIHKAYSEAGADV
LETNTFGANRIKLTEHGLGEKVREINVAAAGIARQYAMDNLYVAGSMGPCLKSGQILGEN
RREELSEVFSEQAQALKEGGVDLILLETFSHSEELILAAQAAAETGLPVCGCFTLTEEGY
TPGGESLEVLMQGLDSCEALDLVGLNCGTGPSHTYNWVERALPLTQKPLIAMPNAGFPKE
QDGRMVYLTNPEYFASYAQKFIKLGVSGIGGCCGTTPEHILKASRTVKATSLIKQHVEIK
VVDRTASDVQPVPQEEKSRLACLLKQGKMVTSVEITPPRSTDLTGFISKAKACAYHGVDA
INIPDGPRASARVSPMIAASIIQKEAGIEAVLHYTCRDRNLLGMQSDILGSVAAGLNNFL
VITGDPPKSGDYPEVTGVFDVDSIGLTQVILGLNYGRDFGGNPITPPTGIFTGVGANPCA
VSPKLELDRYRRKLEAGAEFAITQPVFDPDALLKFMDEASAFGTIPVVAGVWPLVSFKNA
EFMRNEVPGVEVPDSVMERMSRCKTREEGIAEGIRIASEICRTIEPYVQGYQVSAPFGRV
ELALKVLGMDTTI
>A0A8D0DFT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sander lucioperca|TrEMBL
MVNQVQRGDGSWQSCKSDSSGASNSSESSKESSRSSTPVLDVDRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGTGGPLFIDITWHPAGDPGSDKETSSLMIASTAV
NYCGLESILHLTCCNQTKEKISGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATD
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNY
GIKQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LKMWGDELMSEESVYEVFTCYITAQPNRSGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIAGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVN
YHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWKVIDDMFELLDATPEPNTTEWSIF
YALPKKRCYLQNR
>A0A7Z8JTE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMTTAKQLASFSPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEVHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A357HGW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEIIANYKAQGKTFYSFEFFPPKTDFGLDNLYSRIDRMASFHPAYIDITWGAGGATA
DKTL
>A0A1B7YIU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum higginsianum (strain IMI 349063)|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTAMGLSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKDE
YRDTEDSDVDDIEDFVWAVDLVKYIRKNYGDYFCIGVAAYPEGHADESHPQGQSFEHDLP
YLVEKVQAGADFIMTQLFFDIKAYDKFENILREHPSGAFKDIILLPGLMPIQSYQMIKRT
TKLSHAKIPDNLMARLDAAKGDDEKVKQVGVDILSELVEQVKEVKNRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDPQLDNEEAVIDDGPGVPVSIPAVQLNGLSPITPAARALSGRRH
SSMGSSDPHNRIIVSSASNPAYEMTTAGLMASEPVNTRANTLAISEGVGAVGREATWDDF
PNGRWGDARSPAYGEIDGYGVSLHMSVTQAIRLWGTPKTIQDINNIFIRHIKGQLNAIPW
SEEELLPESNMIQQELLELNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVEL
FIPSSDWAGLVARLNEVTDNTICFYAANAAGDFVSSDSSGGLVLEGTEASTNAVTWGVFP
GKEIITPTIIEEVSFRAWAEEAFKIWGEWSKVYGKGSESEALLERIRTEYWLVNIIHHDY
VERDALWKLLSGEKEN
>A0A2E5W257|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIRDKIKKPHRPVVAYEILPPREKDGTLNSYAETISSLLSQTHIDAINIPEVHDEVGRG
DRPIVNQKRGEPREFGRLLQDIVGIEAIINRVVVYDDYDTQMRWLEETNKDFEIENMIIV
GGESSSVKYSGPTVNEALNAISNIYNKKVGDIFCGGISIPSRKEESKNLIQKSQHGSEFF
TTQVLYDSENAIKMINNYQKRCHELNTFPRRILLSFAPVSSQKNIEFLKWLGVEIPDNTE
RYLQGRPGSMKERSLDVAIEVLNEILSNIEKNNLKVPVGLNVEHIMSYNFQSSVEMLQEL
ARIYREFCIKTQNYTL
>A0A450S912|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. FW|TrEMBL
MIKIMDDQGSKDRVFSFEFFPPRTPEGRDKLRATWQRLSELNPHFFSVTFGASGSDQSGT
LETVREIQRHSGIDTAPHLTCIGSSRVRIREILERYLATNIRRIVALRGDFPPDMTEMGE
FRYANELVAFIRAETGNDFHIEVAAYPEFHPAAPSASMDLENFKRKVEAGADSAITQYFY
NQDAYLRFVDSCNRIGVRIPIVPGIMPITNYVSLARFSERCGAEIPRWLAKRLEGFGDNM
DALQAFGIDVVTELCHRLLEAGAPGLHFYVLNRAEPVATIWKNLGLSKIP
>A0A2K9MBB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGEHFHIEVAAYPEMHPQARNFEDDLHNFVRKANAGANSAITQYFFNADSYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A2R4XLF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orrella marina|TrEMBL
MSVSTGQQFSLEFFPPRDEAAQARLVECAQSLKVIDPSYVSVTFGAGGTTRDGTLETVQT
LTGMGFDAAPHLSCIGSSRDQLRAMLDHYREMGVRRIVALRGDLPSGMGSMGGQGSLAHA
VDLVRLIREHSGDWFHVEVAAYPEMHPQASGPQKDLRHFVEKVNAGANAAITQYFFNADA
YFDFVDRAQMLGVTIPIVPGIMPITNYSQLIRFSDMCGAEIPRWIRLRLAEMGDDRASIR
AFGIDVVAELCQTLLENQVPGLHFYTLNNSAATLAIWKSISG
>A0A5Q0BSR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methylospira mobilis|TrEMBL
MNSQRAYPKSFSFELFPPKTEAAELALKNTVAQLRQINPSYCSVTFGAGGSTREKTFETV
VSIQEGMGIACAPHISCIASTRSYIREMLDAYREQGIKRIVALRGDMPSGMLTTGELRYA
NELVEFIRQETGNDFHVEVAGYPEVHPQAANAEKDLLNFKRKVEAGADSAITQYFYNAEA
YFRFIDDCEKQNINIPIVPGIMPITNYTQLARFSELCGADIPRWIRKRLEVFGDDRVTIR
TFGIDVVSKLCRRLLEQGAPGLHFYTLNQSDATLAIWHNLGLHGNNPA
>A0A3G5T526|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium YIM 96077|TrEMBL
MMKQLAPGVKRWRQTLLSNPRFEVLPVAGALERVTRLPAGATVTVTASPRRGIEDTIAFT
ETLAARGYAAVPHLAARQFSDETQLTNALRRLHDAGVDDLFVVGGDASASDGAFPDGLAL
LKAIDASGYRFGRIGVPSYPEGHPQIDDDTLWEALRAKRPYATYTVTQLCFDSDAIGRFA
ASTRMHGFDLPIVVGVPGVVAPAKLLRMSLRVGVGDSLRFVRGNRSMARRLLTPRAYRPD
GIVRGLAGQMAEGRVTLAGLHIYTFNETSATVRWLEQRLGHAADEDIPAHVYKDVHEKRP
ADDHAV
>A0A2D9IVK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVTDYLKDXNKTYFSFEIIPPFRGGSIDKIFSLVEELMKFEPPXIXLTSRSAEEYYQDD
GSGNLVQHIRRKRPGTIGISAAIKNKFNVETVPHLLCSGFSKEETEDALIELNYLGIKNV
LALRGDELRKDRNEINSKISNGYASDLVKQIKNMNEGKYLEPLIDPTKSDFCVGVSGYPE
KHFEAIDFKTDIKYLKEKVENGADYIVTQMFFDNKVYFDFVERCRKEGINIPIIPGIKIL
STERHLTALPKHFYISLPQELKNSVEGKTKNEIRNSGKKWAINQIQELLEGSAPCIHLYI
MASAKLPSEVVSEFI
>A0A5F0LWQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. 3C11|TrEMBL
MTQHNFSIEFFPPKTPEGTEKLRVTRAKLAELQPKYFSVTFGAGGSTQQGTLDTVLEIIR
EGHVAAPHLSCIGSSRDALRAILTEYKSHGIKKLVALRGDLPSGFGAADFSSGEFRYANE
LVEFIRAETGDWFHIEVGAYPEMHPQAKSPQDDVQNFARKIKAGADAAITQYFYNPDAYF
NFVDEAQKLGVNAPIVPGIMPITNYTQLMRFSDMCGTEIPRWIRLKLASYGDDADSIRAF
GLDVVTQLCEQLLEGGAPGLHFYTLNQPAATMAIWQRLVD
>A0A345V3W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVTEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A5E6T0P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKTAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A5E7FMJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLKQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLHNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQRFG
EQVITQMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A5E7SAV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLAQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A5E6P4X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYKAAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHIEIAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>M1NNI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium halotolerans YIM 70093 = DSM 44683|TrEMBL
MNVATMHRRATSRFSASAPLDTESADTGAHLTGAHTAPAPTAAARPRTALSFEVIPPRHD
ADQAKIADLLATLESYNPDYIAVTSSRRSGWLEGTTEFIAQISATTRMRPLAHLACTAGD
RGELLTWINRLVDAGVRGLLALRGDLDEGQTGLPPGHLQHADELVRLIRDVEKQQALRFA
AGRLAVGVAAYPNGHAESANYDEDIDVLLAKQRSGADFAITQLFFDAEDFLRFAERARLA
GVTIPLIPGIMPMTSVQRLRRMGQLSGLTVPDRLIRRLETAGPEGEHEVGLGLTAELGQT
ILDAGTGGLHIYTHNKPDVTTELLDRIGVAPRPPGG
>A0A6I7R836|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sanguinis|TrEMBL
MYQRLTSTRLSASAPLDRLDEDVNPSAAAPRRSTRTALSFELIPPRHDADTALLDNLIAG
LAEYNPDYVSVTSSRRSDWLEGTAALIKRIAETTDLKPIAHLACTAGTRDELTEWIRTLI
DAGVRGFLALRGDLPEGETSLPEGYLPYATDLLNLIQEVQDEQAFRLAAGKLALSVACYP
SGHAESKNADMDLDVLLAKQRLGADFAITQLFFEAQDYLDFVERSRLAGVRIPLIPGIMP
MTSLRRVERMGVLSGITVPQRVTDRLSKASTPDEEYEIGMAMSSELTREILDAGTGGLHI
YTHNNLAVTRDLLSRINL
>A0A6V9XN29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Decatur|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1C5NSF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MNIANLFQSKKIVYSLEVFPPKKTSSVDTIYNTLYGLRGLPADFISVTYGAGGSDTQRSK
TCEIASLIKSEYQIEPVSHLTCLNSTKEDIRQTLDSLKANGIQNILALRGDKGPAVTPKN
DFTHANELAEFIKAYDPSFNVLGACYPECHCDSETIDQDIENLKLKIEAGASHLITQLFF
NNNHFYEFMDKAIQKGITVPISAGIMPIINKSQIERTVSMCGASLPRAFSTMINKYADDP
QALKDAGIAYAVNQIIDLISNDVRGIHLYTMNNVETASRITESIENIIKSQNRITKR
>H8FJE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. mangiferaeindicae LMG 941|TrEMBL
MPSGASTITDTYSLEVSVKDIGALTNAAPRILPGSDMFIPYLPGQTEAARLAAAQRVRRL
GFEPVPHLSARRIGSLEELQAVIARLVGEADVTRCLVIAGDPSTPEGPFADSVSLIETGV
FERSGIRTIGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDADIVMTW
LEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGNAGPDR
FVDRLVSRLTEAHGDVRLHLFPFGGIAQSVEWVAHYRSCEASQDRVSSVAAD
>A0A060R5R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucinivorans hirudinis|TrEMBL
MKITENFQSSKTLFAFELLPPLKGDNIDTIFDTINRLSPFDPSYINVTYHREEIKFIERG
DGLLERRTIRKRPGTVGIAAAIASKYNIEVVPHLICGGFSKFDTEDALIDLNFLGINNVL
ALRGDNIHGERSFNPSQNGHSNAIELVRQIAAMNRGEFLDSEMEITKPTNFSIGVAGYPE
KHSEAANLASDIQHLKAKIDAGAEYIVTQLFYDNSKYFEFVRLCREAGINVPIVAGLKPF
TTFKQLSLLPQIFHVDLPEDLVREVEKCKNNGSVREVGIEWAIAQCRQLKDAGVPALHFY
TMGKADNVEQIARAIF
>A0A1C5E3K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Cmuel-A718b|TrEMBL
MLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKATQE
IAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHPQGV
KYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFFRPE
DYLRMRDRVVAAGCETPVIPEVMPLTSVKQLERFSQLSNATVPASLKERILAAKDDPAAV
RSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A6N2VED2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia muciniphila|TrEMBL
MHLRERLQSGAGPSLSFEFFPPKNEQAAAALYQTIRELEPYHPSFVSVTYGAGGSTRELT
REVVLRIQHESRIPTVPHLTCVGHSREEVWSILDQYAQAGVRAVLALRGDPPRGTENYNR
DADAFRHAAELVAFIREYNESGRHPDPDGFAIGVAGFPEGHPSTPNRLREMDFLKAKVDA
GADYICTQLFFDNHSFLDYRERCLLAGIKVPILAGIMPVTSLSGMNRMAELSGGTCFPAR
LLKALKRAGSNPDAVQEVGIQYASSQCAELLDSGVDGIHFYTLNQSRATRQIYRNLGLKD
SLQLLEHGEDK
>A0A7Y9LCH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microlunatus parietis|TrEMBL
MAPETTLDRRPGMTTRTDPHATIAELLAAPTGPLFSFELFPPKDDDQRRTLWQTVRRLEA
LGPDFVSVTYGANGSSRERTIEITEAIAQHTTLRTMAHLTCASQPAEQLRRVIGWYAAAG
IRHVMAIRGDMPGGPTVPWEQHPQGLRNATELVELVRSLGDFCVGVGAFPDLHPERYDAE
LDARLLVEKAQAGASFAITQLFFTPSRYFELVDRVRSLGCDLPIIPGIMPVTRLSQIQRF
AELSGADLPAPVVARLEQAGDDPAKVRQAGTDIATELCAALLEGGVPGLHFLTMNRSTAT
REIYARLNPSHG
>G5LWJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Alachua str. R6-377|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3A6MNE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulforudis sp|TrEMBL
MSGGSRLRQVLESGAFAVTCEIGPPKGALVNTLREKARLVRDYVHAANVTDCQTAVVHLS
SIAAAVHLQSEGVEAVAQMTCRDRNRIAIQSDLLGAYSLGIGNLLCLTGDHQRFGNHPQA
KNVFDLDSIQLVDMVRGMQDEGLFQCGEPIRAGAPQFFLGAVANPFADPFEFRVLRLEKK
VNAGARFIQTQSVFDLERFRRFMEMVRARGLHHRCYILPGVSPVRSIRAVEYIRDRVPGL
TIPDQIVERMRAATDPAREGVEIALELIAGLREIEGVAGVHIMAIAWEQVIPELVQRAGL
GSKL
>A0A0C7N1X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea lanzarotensis|TrEMBL
MSTIKERYESSPGPFVSLEFFPPKTQSGKQNLMARMGRMTALNPLFLTVTWGAGGTTAKK
TLELAALAQRELNIPVCMHLTCTNTSREVIDNALKEAHKADIRNILALRGDPPVGEDWDQ
GSAPSDFKYAVDLVRYIKKEYKDDFCIGVAAYPEGHCEGEADVMDHSSLRDLPFLKEKVD
AGADFVITQLFYDVEKFLSFEKLFREQVSSTLPLFPGLMPINSYQLFNRASKLSHASIPA
SILNRFPSEYHADDNKIRAIGVDVLSEIVETIYERTEGRVKGFHFYTLNLEKAVAQIVTN
APCLAKMFEEEKDDDLVDGIEEIALEDSDTSDSSNMKKRRRQSSSHNPDRTSNRVLIDDE
DRNIVKGREPSGAPSRKVVLSISKGSGSLGKDATWDEFTNGRFGDSRSPAFGEIDGYGPS
LKVSNQKAYKVWGQPQCVKDIQTLFKRYLEGALEALPWSDLGLSPETALIQEELIQLNER
GYLTLASQPATSSTSSTDKIFGWGPRGGYIYQKSFVEMFVHKEQWNNVLKPKLEPLSPTV
SFYVGDSGEAFHSSLETDGSSVVTWGVFPNSEILQTTIVEEESFKAWRDEAFSIWLEWSK
LFPRGSATNSLLRQVHKDYYLVSIVHHDFSQCDALWDLLLT
>A0A0C7MZ47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea lanzarotensis|TrEMBL
MRVSEKLQKNLDSAEKSKATFSFEFFVPKTSQGVQNLYDRMDRMYQTRPQFIDITWNAGG
KLSQLSTDLVSTAQSVLGLETCMHLTCTNMPVELIDDALAKAYESGCQNILALRGDPPVT
TGEWKQCEGGFAYAKDLVKYIRETYGDHFDIGVAGYPEGHPEEEATPQLIDFLKEKVDAG
ANFIITQMFYDADIFIDWCRQLREVGIDVPIIPGIMPITTYAAFLRRANWCQIHIPDEFQ
AALDPVKEDDQAVREVGTKLLAAMCQKLLDSGYVTHLHMYTMNLEKASLMILDRLGLLAE
EEDIFRDEVVPMPWRKSLHPQRKNESVRPIFWQRRPYSYVARTSEWSADEFPNGRFGDSS
SPAFGDLDLLGSSLIRQSPQRALELWATPKTITDISNLVIGYLQGKIKCLPWCDVALNHE
VDSIMPELLDLNKHQIVTLNSQPRVNGIDSSDSVFGWGPKNGYVFQKEYLEFLLPKSKLS
QFIDLIGNGTSLTYFAVDAADKLYSNHPDDTAANAVTWGIFPGREVLQPTIVEKVSFLAW
KEEFFHILEEWRLILSQDGHNDSATLLDTLTSDYALVNIVDNDFVTPGDRIHDHLKSLY
>A0A1G0DZL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium GWF2_41_13|TrEMBL
MIMLSSKINLSFEFFPPQDAEGLDKLLLVAKKLSALNPDFFSVTYGAGGSTRDNTKQTVQ
ALKENFNIPIAPHLSCIGSTREVIQRILDEYIDMGVKKIIALRGDLPSGMRNVGDFSYAS
DLVSFIREHAGDHFEIKVAAYPEFHPEAKSPQDDLSYFKHKIEAGAHAAITQFFFNTEAY
LHFVEDCREMGIITPIIAGIMPISNWERLMKFARTCGMDLPIWLQRRMDALENDEAMKRE
LGIKILTNLCFRLKQAGVTDFHFYTLNQSKLSLIIGESLLRS
>A0A231H5G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia cerradoensis|TrEMBL
MVGQLGRRPDGTIPFSVEFNPPRDAAAEARLWRAAREFERMHPAFVSMTYGAGGSTRDRT
ARITGQLARETTLLTVAHLTAVGHSVAELRSIVGSYADAGIRNMLVLRGDPPGDPLGEWR
KHPDGVEYAEELVRMVCELGDFHVGVASFPQGHYRSPDLDHDTRYLTAKLRAGAEYSITQ
MFFDVEHYLRLRDRVAAYDAEQGAKPIIPELMPITSLRTVQRAEELSGRPLPARVMQRLE
QAAGNDPEANRNAVRAVGIEIATEIGQRLIDEGAPCLHFITLNFAKATTEVLTNLGYTVT
PAAVSA
>A0A416H0G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. OF02-6|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPGTIEHLMKYRPEYISCTYGAGGGNVGANRE
VCQMIRNAGTIPVTHFTVIKNTKEGIRQQLERYLSDGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>B6XJN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia alcalifaciens DSM 30120|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSTEMEQTLWKSIDRLKVLKPNFVSVTY
GANSGERDRTHSIIKDIKDKTGLVAAPHLTCIDASRDELRAIARDYWDNGIRHIVALRGD
LPDNSQKPELYAEHLVELLKTEADFDISVAAYPEVHPEAKSAQADLINLKKKIEAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPSWMNRMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPQ
>A0A1I6ZEG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudovibrio denitrificans|TrEMBL
MSEHSIDRRFRLNGASDISVSFEFFPPKSEKMEQQLWSSIKRLEPLSPSFVSVTYGAGGS
TRERTHSTVSRIVNETALKPAAHLTCVDATKEEVNEVIQAYWDAGVRHIVALRGDPAAGL
GEAYHPHEGGYQSTADLVASIKTIGDFEVSVSAYPEKHPESPSWDAELDVLKAKVDAGAT
RAITQFFFDNDHYFRYVDRVRAAGINIPIIPGIVPVTSFKGISGFAKKTGASVPGWLAHR
FDGLDDDPRTRELVAAAVAAEQVMSLADDGVEDFHFYTMNKADLVYAICHMLGLRAKQDV
KASVAA
>A0A2E0ALV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp. NAT70|TrEMBL
MRSALQSALQSGAATITAEVMPPRGGDPSHTLAMAECLRGFVHAVNVTDGSRAVMRMSSL
AVCKLLLDVGLEPVLQIACRDRNRIALQADILGAHALGIRNVLCLTGDPVRAGDQVDARP
VNEFESVKLLRQISAFNRGEDPVDGVLADGAIDLFAGCAADPESSSWSGLQRRFIRKYEA
GARFVQTQMVMNAKALERFQNELAGPMQIPVLAGVFLLKSARNAHFINRVVPGACIPDSL
IARLESASNPAMEGVAIAAEQLQRYLGIVQGVHLMAIKAEQRIPLILQQAGISLPQM
>A0A653LQZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 8AS|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVGVPTAPHLSCVGDSKDELRSLLSQYKNSGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGDHFHIEVAAYPEVHPQARSFEDDLQNFVRKCRAGANSAITQYFFSADCYFY
FVERVRKLGVELPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDLESIQAFG
EQVVTEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7C1DD87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfonatronum sp|TrEMBL
MKISDLLRKAERSRLSLEFFPPKDKALWPRFFDTVQELRSLDPLFVSVTYGAGGSTQSST
LEIVTRLKRDYALEPMAHLTCVGASAAGLKAFLDDLTQADVQNVMALRGDPPKGETTFTP
SDEGFRHACNLVEFIRKGYPDMGIGVAGYPEGHPEAVSLEQDLLFLKHKLDLGGEFAVTQ
LFFDNQRYWDFVARAREIGITKPILPGIMPIFSLKVIQRITSLCGARLPGPFLARLEQAD
VQGGDEAVQKVGMAQAAAQIRDLLDKGVPGVHLYTMNRADGCLRIMELAEELADKSDR
>A0A7W8ZM15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter cryoconitis|TrEMBL
MKITDHITNAKGKTLFSFELLPPVKGKSITDIYAAIDPLMEFNPPFIDVTYHREDYIYKQ
HDNGLLEKVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADSSFIPTPGGHAYATDLLGQVNDMNNGKYLFEDHSAFQTDFCIGVAGYP
EKHFEAPNLKTDFKYLKQKVDMGAEFIVTQMFFDNSKYCDFVAQCRANGINVPIIPGLKP
LTSSKQLISLPKIFHIDLPEDLTEAVQECKNEKEVKEVGIEWMIQQCKELIKVGAPVLHF
YTMSNPEPTQRIARAVF
>W5W0K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kutzneria albida DSM 43870|TrEMBL
MAPLPGWKKSADFVVAQASFDLAQLLRWRERLDYDGQVFAGVLVVASPRMARALAEATAQ
ISVPAELLAELEHERDAGVRKAAELVAQLRATGSFDGVHLVPVGRYKSVAALLSRAV
>A0A7T6XWD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium digitatum|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEAAENGFCYAKDLVKYIRNKYGNHFDIGVGGYPEGADDNADVDQLIDHLKEKVDAGSSF
VVTQMFYDADNFIEWVKKCRAKGITVPIIPGIMPIQTYASFIRRSSWTKVHVPPQWMEAL
EPVKNDDSAVREIGKTLIANMCRQLIAAGIKHLHFYTMNLAQATQLVLKELDLSPSEESP
IQRALPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSVKDISDIFVDFLTGKLDRLPWSDSPITTEAHEIQEDLLK
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSSLIDELITRIEKND
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCYDAASPSRKLIQQVMDDWYLVNIVDNDFHRSNAVFELFNGLEIKGLNVEVDGKPLTNG
HAEQNGVAAN
>A0A7K2RKN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8367|TrEMBL
MALGTPSTRTDRARTVRDMLATGKTVYSFEFSAPKTAKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHITAVEHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWISHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSADWDSDVRYFVD
KCRAGADYAITQMFFYPEEYLRLRDKVAAAGCDTPIIPECMPVTSVRMLERLPKLSNADF
PPALKERILTAKDDPAAVRSIGIEFATEFCAKLLDEGVPGLHFITLNNSTATLEIYENLG
LHDQRA
>A0A1X2I4Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Absidia repens|TrEMBL
MKVIDKIRKAEEENRVYWSFEYFPPKTAQGTQNLFDRIGRMKQYGPEFIDVTWGAGGTTS
ALTTEIVKHAQSVKQVETMMHLTCTNMPSEEVDKALEAAKACGCQNILALRGDPPHGQDK
WESCEGGFNNAIDLVKYIRLKYGDYFGIAVAGHPEGHIDNPSKEDDLNHLKAKVDAGADL
IVTQLFYDVDMFLEFVKKCRDIGITCPILPGVFPIQNYQGLKRVISFNDNYVPEHIWNDL
EPIKDDDAAVKEYGIQLTIKFIEKMLAAGIKGVHFYTFNLERSTRLILERLNLIQPAPAA
PAISSVQQDIPTAANVAQSSAQQTKA
>A0A2A9GP88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioclava sp. ES.031|TrEMBL
MTTPKVSFEFFPPKTLDASFRLWETAQVLAPLKPEFTSVTYGAGGTTRKLTHEAVGTIHK
NYGLNVAAHLTCVEATKAETMEIVDAYAEVGVTEIVALRGDPPQGAAHFTPHPEGFASSV
ELIEALAEDGRFTIRAGAYPEPHPDAADNMADVRWLKRKVEAGATSAITQFFFEPETFFR
FRDACEKEGIDAKIIPGILPIQSWKGAKKFAQSCGTSIPAWVEEAFEPAIRDGREHLLAT
ALCTELCDKLIEGGVEDLHFYTLNRPGLTRDVCHALGVTPDTVLEKVA
>F0FFD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis SK353|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A4W3HD31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callorhinchus milii|TrEMBL
MMVKQRQHNGQLSKSGESCSDSSSRESSRSSTPSLESDRLREKMRRRIESGDKWFSLEFF
PPRTAMCHCRVNEFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETLL
HITCCNQSKEQITEHLQKACRLGLKNVLALRGDPIADKWQTEEGGFNYASDLVKHIRNKF
DDYFDICVAGYPTGHPECTSYEEDLKHLKEKVEAGSDFIITQLFFKPQTFLKFLKDCRAI
GITCPILPGIFPIQGYHSLRQLVKLSKLQVPQEIKDIIEPIKDNDAAIRNCGIDLATDLC
KALLTSGAVPGLHFYTLNREVAATEILRRLGLWIEDPRRPLPWAVSANPKRKVEDVRPIF
WASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSNCAKEELLKMWGEELV
NEEHVFEVFTAYITGESNRNGTKVTCLPWNDESLAVETNLMKAELQKVNRRGILTINSQP
NINAKSSTDPVVGWGPEGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVKSE
NINNASDLQPNAVTWGIFPGREIIQPTVVDPISFMYWKDEAFALWIERWAKLYPEESPSR
QIIQNIHDNYYLVNLVDNDFPLKNCLWQVIEDMFLLKSIEKPLPLVP
>A0A6B3A3F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7909|TrEMBL
MRTSPELFTAGRPAFSFEFFPPKTESGERTLWEAVRRVESLAPQFVSVTYGAGGSSRERT
VEVTKRIATETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPRGAWA
PHPRGLSYAYQLVELVKELGDFTIGVAAFPECHPRSADRESDVRHFVAKCRAGADYAITQ
MFFQVEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFARLSGAAFPEDLAHHLEAAR
DDPGAAHRIGVAHAVAMAERLLSEGAPGLHYITLNRSLAALEIHRAIDHTRSTRAVISPS
>A0A1V5CVM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdus sp. PtaU1.Bin058|TrEMBL
MANPFADPFDYRVTRLSKKVAAGAEFVQTQCIYNLKRFKEWVNRVRERGLDKKVYILGGV
TPLKSARMAEYMSKQVAGMDVPDDIIDRMKGVEPKEQRREGIKIAVETIMALKYMEGVHG
VHIMAIEWEDIVPQIVEEAGLYPRPKTSEE
>R7JR40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. CAG:37|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A2P2JJG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophora mucronata|TrEMBL
MKVIEKIRAALGGDADGGGAAAGSSTTTLPNGGPRNVVFSFEFFPSKTEDGVDNMFDKME
RMVVHNPAFCDITWGAGGSTSDLTLDIANKMQNIICVGTLMDLTCTNMLVGKIDEALETI
KANGIQNVLALRGDPPRGQDKFVRIEGGFACARDLVRHIRSKYGDYSCWLSRFFL
>A0A8G2BZF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomicrobium norvegicum (strain DSM 1741 / NCIMB 8310)|TrEMBL
MKQHILTALGERVVVADGAMGSLLFDRGVDSSSCYDVLNLTDPALVQSIHKAYAGAGAEI
IETNTFGANRVKLGRFDLAHRAREINLRGAELARSQAGPGRWVAGAMGPLGRMGIDPISQ
EELEDIFSGQALALMEGGVDFIMLETFASLSLLLTALRGVKASVSVPVVAQMVFTQRGRT
HSGRTARECFDALIRAGADVVGLNCGIGPKNALEVVQGLGPVTVPLSVLPNAGFPESSGD
RLIYASSPEYFARRTAACAAHGARLLGGCCGTAPEHIAALVRALDAGSPEARIVSASPDE
VNTQTAAPTRLSRRLVEGKVILVELDPPKHLDVEPVLAAAEALSAAGVDAITIAENPLAV
PRLSNIVLAGMVRARTGVEVVVHMTGRDRNLVGMQSTIMGLAASNLHNVLAVTGDPPSAG
SAERVSGVYDLRSLELMALLAGFNEGRNHYGDSMRLPVNFCIGGAFNPNTRNMALQVGRM
EKKMAAGASYFLTQPVYSKERVDEILTATAHIKAPIVLGIMPLASSRNAEFLHNEFPGIE
IPSETRERMARAGEHGQEEGVNIAWELLEYAWPHFAGVYIIPPFNRHAMALELMRRLGR
>A0A7G9L758|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. L12M9|TrEMBL
MKITEHIKKADGKTLFSFEIIPPKKGNNINDLYNNIDPLMEFNPPFIDVTTSREEYVYIN
KGEGLLDRKITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFTKEETEYVLVDCHYLGIDN
VMALRGDAMSHQKYFTPNEGGNHYATDLVKQINDLNCGKYLHDVIEATNKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFAFVEAAKEAGINVPIIPGIK
PIAVKRHLQLLPQVFKIDLPETLISSVENCKTNKDVRQVGIEWAIQQSKELLAAGVPVLH
YYSMGKSDNVHAIASELF
>A0A093ZSX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4246|TrEMBL
MHIKDMLNQGEQAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHA
QLTCEMVSVAQSVYGLETCMHLTCTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEK
WVATDEGFQYARDLVRYIRKTYGDHFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATF
IVTQMFYDVPNFLDWVRKVRAKGINIPIIPGIMPISTYASFLRRCNHMNAKIPPGWIEAM
EPVKNDDAAVREIGRGLVTDMCRAILESGINHLHFYTMNLAQATRGVLEQLEMLPSEARP
LKQALPWRQSLGLGRRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGEPKSVKDIANVFLRYLSADIESLPWSEAPISNEADVIKQQLVK
LNERGLLTINSQPAVDGVKSSHPVYGWGPLNGYVYQKAYLELLVAPELIDELLDRIAKDP
EVTYYAVTKSGTLRSNAPGDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHDASTPSRNVIQRVMETFYLVNIVHNDFHQRDALFSLFEGLAVPNIDQPAEGSVAPA
AAPAAPAANGEDAPPAIVSNVLPVA
>C0BM51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteria bacterium MS024-3C|TrEMBL
MKITQHIAAAKGKTLFSFEIVPPVKGGNIQELYNNIDPLMAFNPPFIDVTTSREEFVYLK
KEGLLEKKLTRMRPGTVGICASIKHKYGVDTVPHVLCGGFTKEETEYLLVDCQYLGIENV
MALRGDAMAGQRYFEPTPGGHTYAKELVGQIKDLGTGKYLHEEIESAHSSSFCIGVAGYP
EKHMEAPSLQQDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVAAAKEMGIDVPIIPGIKP
IAVEKHLQLLPQVFSLDLPQDLIDAVSDAKDKAAVRQVGIEWAIAQSKELLAAGVPVLHY
YSMGKSSNIEAIAAEVF
>A0A1X7P923|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter oskolensis|TrEMBL
MSATENPPEPHCPRAVPFSFEIYPPRTVAGAAALTSTVDRLAEARPSFISVTYGAGGSSR
SASLEILRYIHESTPSEALAHLTCVGSTHAEASRLVHEFLEAGVTRFLALRGDPPEGTPE
GGAFLGELGSAAELVQLIHRVQAEREPYGTVAVPGRPNALRVDVAGRRRAQVAVAAFPNG
HPRSRSRSQDIDALLAKEAAGASFAITQLFFHAADYLHFVERARAAGVRMPIIPGVMPVT
GPARLRRMLELSGEDLPAELAIALDVEPDDDARRRIGIAHAAALVRTLVEGGAPAVHLYA
FNRHEEVLGVLAESGLLPREPAVAGLAHPSLSPTSESPS
>A0A1I2K260|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fontimonas thermophila|TrEMBL
MSASSIHFSFELFPPRTPAGAEKLPAVVSRLAAVGPAFFSVTYGAGGSDQEGTYETVMRI
AEDTGIETAPHLTCIGSTRAKIAALLQRYRDSGIRRIVALRGDLPATAASAAAPGEFRYA
SELVRFIRETHGQHFRLEVAAYPEMHPQAPNPDTDFENFRRKVEAGADGAVTQYFYAAEA
YFDFMERCARAGITIPVVPGIMPITNFAQLTRFSAACGADIPRWIRLRLEQYQDDKQALL
DFGLEVVTRLCRTLLDEGAPGLHFYTLNQAEPTLRLWKHLGLPVR
>A0A3E0L998|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis flos-aquae DF17|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFDRLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A2M7SJL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_10_14_0_8_um_filter_43_12|TrEMBL
MHFQELLDSKKFLVISELQPPKGTDLTEFYDYAEKMRGRIDAVNVPDLQSAVMRLGSLSA
SYLLKEKGFTTICNMTCRDRNRLALQSDLLNISVLGIENIVLSRGEEPSLGDHPDTKPVF
DLTPLELISAIRDLQKGYDMAKSDLHGTPKFCVGSTVNSSAQRGALDLEIKKMEEEIRAG
VDFFLTTSVFELDIFENFIRKIEYLKVPIIPGIMILKSVGMARFMNKHVEDVFVPEILIE
RLMKSADKPKTSVEIASELINGLKPLCQGVHLIPFGWEDKVPSIIEKAGLY
>A0A436KES0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.002.04.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A4R4UGC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. KC606|TrEMBL
MMRHRNRADVLHRLLSRARYEVLPTASVVDEVSATLPTGATVTVTASPSKGLEATLDLSE
RLAALGFDVVPHLAARMIHGPGELGEITNRLARAGITKVFIPAGDADPPAGAYHSALQVL
EDLACAGNPFSEVGITGYPESHPRIHDDLTIQAMWDKRRLATHIVSNLTFDPGVLSAWVR
RVRARGVTTPILVGLPGPVERTKLLRVATKIGVGESAKFLATNRSMFARIAAPGGYDPLR
FLGRAAAVLGRDDMFVGGLHLFTFNQVAETEAWRASQLARLREHRLTPVIAEGRDAMWVG
GGE
>A0A856MC54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brasilonema sennae CENA114|TrEMBL
MLDTITPTALTSFRTAAKTGKFLITAEVTPPKGGNPEHMIQMAATLKGRVHAVNITDGSR
AVLRMCSLVASAILLQNGIEPICQIACRDRNRIAIQADLMGAHALGIYNILALTGDPVKA
GDHPDAKGVFDLEGVRLLQLIHKLNQGIDCNEKPLSDGALDLFPGAAVDPQCASWSGLQS
RFERKLAAGAQFFQSQLITDFERLEKFMDKIAAGCDKPILAGIFLLKSAKNAQFINRCVP
GVNIPDHIIDRLAQAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIVPILDMAGV
GVVTK
>A0A847INB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKLTDIFKVSEKTFSFEFYPPRDEIAAVDFGLNIGQLIKLSPSFVSVTYGAGGSTQSRTF
DLVDYLKNRVGLNTVAHYTCVGSTRSRTLEDLKTLRKLGLQNFMLLRGDPEVGSKYGFIP
CYDGFANATELITFAREFIDDCCIGGGAYPEVHPESPSAEIDMRNLKKKVDAGCDFLITQ
FFFDNKRYFDFVSRARKAGIKCRIIPGIIPLTKYSQLERFVNLSRASVPPAFLEQLESNR
YNPEAVYKAGMDFAIRQCRDLLMLGAPGLHFYTLNKSRATVEIYQTLMVR
>A0A7J6NYW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perkinsus olseni|TrEMBL
MERPARSDESSSSAKEKDEGDGSAPNHRRYYPDDLRHYRVSNLVRSWLLCSELEVSDLQQ
RVHDGTFSTCESADVVTPSAPGLQRLTFPDNAYPGDPVYEEVMANWKQLLALIILGLLRL
DDHHHVQHYIDALNVWQTAKQSASESLTDYFYPLLATVNHQWAKIFNKRLAEDDIAPSDV
TVPLAQRLLLEIESSRRDYGSLLPWEQLRLSYETPAVSDEPIASSGSGKCRRKRSNKKVV
WQEPNDVTSGLFWQYGDFVKGAYTDINTVEPCSSKECSSGSFKSIYYTVLSPASSVSTGK
GKKKKKKKGKGKTPEATSQQAKSSGDKVSGASQSLTPGSSMSHAESDTPSQTIGCTTMAS
DSADVSTEIYALVNAPFKVGDNTLRVYVDTLSTFSLISRSLWDSVRDSDLWEPDCASVET
SDKTLRPGSVATVNGSSSIIAVGSLLVDGLPRTRLKVKVRVVDCLPMVLGPCALILGIQA
LRKLGASIDLGGLAPMVCFSVANISLPLIMKPGDWFRDHPGCVITTVGSKLENLPKCVRS
TQEDCYVDDQKLSDADFEKYIDGMDDDRLRRWVADRFVGYVPKTLDFKLKPGVTPKQFRP
YTIRPDLRHEADELIKTLADEGKLVPATWSLDEYISPVFVIRKRSGKLRLLVDLRSLNYD
INLDPPSSIPHLYESVVSLPKTSKFFSVDDLKDAYWDHEVAPHCRKLLTICLWDRTLWQF
VGAPQGLSLSPESFCDHVWDLLLTALGLRAYRFYRVYIDDIATHGPSPESVRVRRRLLHF
IMAYFDKAFSVKGPVEEVPQTSVDFCGLTLSSDGVSMSRTSVETLEKVLSSPPSTKKDLR
SALGTIQYHRSGFARPELRCSEFGTLLSVLYDKLQQRWKWTDDDQSVWDRVRSLYTNQPL
GKPTECMPLPSDGVWLLVSDSSDSGIGGLLLYLTGMTAELLSELPGEELIHRGTLIGVWS
GILDSLARRWLIYDREMFALITGWKKYWRFLYASIPYDRVRPGSSSMPPVIFMSDNSVVC
SRLCTMKIDDGPGPRVTRWLSWLEDLAPAIRLHAVVRHLAGPANDLADLLSRAFVEPVDN
GQPAQEGSVALIAIESFCSVAEMVRRTEGAVSDTYCSVSISDIYSSLVEGGGKEQVKSLA
RSRFTLDSNGLLFYIDAAGNRSLYVPPDCVVSGSTMPMRQYLIYLVHEHHSHAGIAQTYF
ELRIRYWWPSLRKHVFCAISACNDCALVRSHKQARQVGQDFHRFLARRFDTVAVDLAAIP
PQFQANHGNTILVCVDEATMFTVYARAESATSASLAGCFTRFWISYFGAPSTVRSDNAVY
FKSQFVEEISSIIGLRRVNSLAYNPAANGLCEGRVRLIKRMLKLAVLRGEVSSTALDLYL
SLATSVANVRNLTTLSDCTSAALVFGQNPPRGLLPMLAYAAEQADTDADICSLARDFDVK
GLLSSLRSVLSEADCDRNIHLVDSSTEALDRRIVASHYLRANDGIVVNNLAYYRGEGPFR
IVNVDGNKVTLEDALGYSFHVAIRHVYALQPSTPVWFGIDVATRVAPAAVDLSTVKGIIA
DGSVHYMLFVMDDKKTNTIACGKPVAVDDLSDSIQLHLYERNDTNRYFYPLWVLPDRSVG
SVSDTIVRSKRSPRNALPCLKSYPVSTVPRAIADQLEQVKGDDQKVKDLGVEICVAMCSQ
IMSYGVDHCHSSGGLHFYTLNLESSVSRIIERLMMVDSHVATRALPWRPSKASSRQEENV
RPIFWSNRQKSFIQRTSCWDEFPNGRLGNQASAAYGDFELNFRSYSKETQDKVAADRRRM
WGDHVPNGDHVRRVFTAFIKGEVKRLPWCTESPTEETLFIQKQLIRLNQCNMLTINSQPR
VNGALSTDPYVGWGPGGGFVYQKAYVEFFCPESQLEQLIRGIEGEKYESISYMAVTADGS
KVKSNIPPQGQVNAVTWGVFPNSEIIQPTVVDVTSFMAWKDEAFALWNEWMDVYPEDDHQ
SRQVLSFIRDHYFLCTVVDNDFVAGDLFSKLTKICTPIPWETLRIENPSESDGHEVPEVS
TASFHPQRPSQACTVPSLQTSLAVIAEVYSPRPKPTDLSPRHETKNDITSFAPL
>A0A7X6SCC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKLTDIFKIAEKTFSFEFFPPRDQIAAVDLGINIGQLLRLGPAFVSVTYGAGGSTQSRTF
ELVDYLKNRVGLNTVAHYTCVGSDKKKTLDDLRMLRSRGLQNFMLLRGDPQAGSEKGFIP
CKDGFSNATELIAFAREHIEDCCIGGGAYPEVHPESPDAETDLKNLKKKVDAGCDFLVTQ
FFFDNRRYFDFVARARKEGITCRIIPGIIPLTKYDQLERFVKLSRATVPPVFLEQLETNK
TNPDAIYNIGMDFAIRQCRDLLMLGAPGIHFYTLNKSRATVEIYQTLMVR
>A0A845CGS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium|TrEMBL
MNGLSAIIDSIVSEEVSVSIELYPPKGRKAVERALREVAAIQAAMEVAFTSVTYGAGGST
QEGTLELVLELARRYPDRVVAHLTCVGANEAEISRLMTIYQDNGVRDILALRGDIPEGMT
REEAVSGGFRYAADLVRWLNNLGGFHSIGVACYPEGHPETPDKNADMDHFVRKAEEGADY
AASQFFFEAHVWERFMEQMVSRGVAIPLAPGILPVRDLDQVQRFAKKCGASVPKSVVDAL
APYENNPEAFQESSADLAAAQIGELMTMGVKHFHVYALNRSDIILRIADRLGWRR
>A0A6P6D5P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Octodon degus|TrEMBL
MAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAMNYCGLETVLHMTCCQHSPEEITGHL
YKAKQLGIRNILALRGDPVGGQWESEERGFDYATDLVKHIRSEFGDYFDICVAGYPKGHP
EAGSFEEDLKHLKEKVSAGADFIITQLFFEADTFFRFVKACSEMGITCPILPGIFPIQSY
SSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAICNYGIELAVSLCQELLASSLVPGLHFYT
LNRKMATTTVLKRLGMWTEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQDWN
EFPNGRWGNSSSPAFGELKNYYLFYLKSKCPQQELLKMWGEELSSEESVFEVFAHYLSGE
PNQHGHKVTCLPWNDEPLAAETSLMKEQLLRVNRLGILTINSQPNVNGKPSSDPIVGWGP
SGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWG
IFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSRMIIQYIHDNYFLVNLV
DNEFPKDNCLWQVVEDAFELLNRPAALSWETEAP
>A0A8H7W064|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thamnidium elegans|TrEMBL
MCTDLLLSNKKPWIFSASVFLFFFFFFSSSASMKIIEKIEQAQKDKHIAYSFEYFPPKTE
LGFANLIDRLGRMSQLEPEFISCTWGAGGSTHDRTLELCSTAQSLYGLDTLMHLTCTNME
KEKVDIALKQAKEAGIRNILALRGDPPRGHEYWTPVDSHFTHAIDLVKYIRQEYKDYFCI
GVAGYPEGHIDCPDKEQDMTYLKEKVDAGADFIMTQLFYDSDICIAWIQKCRERGIHVPI
VPGIMPIPTYQSFRRMINLCNVKVPAKVMQDLDAIKGDDQKVKEYGVKLAVSMIQHLYLD
ADICNFHISTLNLERSTRLILEALHLHTVGKSVKAGKVSPWAPIHDPSRAELWDEFPNGR
YGDSRSPAYGEVTHSAGQIISTSQATLKWGQPELEKDIQNLFIKYIRGEINSLPWCDESL
GTETGAIYQRLCEIIERGYWTVSSQPAVNGASSQDNVYGWGPKGGYVYQKAFLEFFVSDT
QIEELLVRLTKDDSITFYATNQKGDFRTNVSDADEAQNAVTWGVFPGKEIIQPTIIEKAS
FEAWKDDAFELWKEWEEQYAPNSKSQKLLCDIGQRYWLVNVVHNDFQQPDLLFDVMLSK
>A0A0Q5M221|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia sp. Leaf336|TrEMBL
MDCTDARFSFELYPPRSDRAAAALPSTIDLLAAARPDFISVTYGAGGSSRASSLEVVRYI
LENTDVSPMAHLTCVGSSHVEANRLIREFLDAGVRRFLAVRGDPPADLAPGEDGLGDIRS
SAELVQLIHRVQAERVPYGELPVPGLPARTVLNHREHVQIAVAAFPNGHPSSHSVSQDID
ALLAKQAAGANLGITQLFFHAEDYLSFAQRAKEAGVTFPILPGIMPVTSPARLARMLELS
GEDLPSDLAIQLEVEPDEDGQREIGIAWATRLAQRLLDGGAPGIHLYTFNQHAAVLSVLD
RIGLLPAAPSPATTPASTPASTSKESEHA
>A0A352YZQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MIRQIRKVGTLNFIKGNFSSDKEIREKTWESVFRTVRQPDWWNGDSEYHPPAYSEPVSDL
EAKLRKGEFVVATEVTPPLGANPAKLVREIELVKPYVTAINFTDSSSANPKMSSLACCKV
ASDLNAEAVLQIAARDTTRTGLQGSAIGAGQFGVKNILCVTGDSSIVGPSPTAGLNFVDI
DSVQMLWILRRMRDEGIYLDGRKIKYPPKYFLGAATSSPSSEPILQAIRDQKKVNAGAQF
FQTNIVFEQGGVELWLEELDKRGVLGKVYILIGLATLKSYKVARYLHDHVPGVFLPERML
RRMEKAGDGEAEEGVQIALELIDXELTGSI
>A0A352MB65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSVIDKIRNAKGTLFTFELLPPLKGHSIEKVYSTIDRLIEFSPAYINFTSHRNEATFRER
PDGLLEKRVVRKRPGTIALAAAVKYKYNIPVVPHLLCGGFTKEETENVLIEMNFLGIDDV
LALRGDPQKGSRTFIPEKDGHTHTFELVKQIVNMNNGRYLEESLEDTAPTSFCIGVAGYP
EKHFEAPNRQVDLENLKHKVDSGAAYIVTQMFFDNKKFFRFRDECRCIGIDVPIIAGIKP
VSALNDINLLPQTFHIDMPHELVLALQKCQSDKDAREVGIEWAVMQSKELIKEGVPGIHY
YTLGRSDNVARIVKAAF
>A0A1H3EJV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium barkeri|TrEMBL
MSSLLQRTLEAGEFAITAEMAPPKGTDFSHILDIADSMIGRVAAVNVTDFQSAAVKASSL
AMCVELAQKGLEPVLQMTGRDRNRIAIQGEMLSAGHFGIKNLLALTGDHTTTGDNPEAMP
VFELDSVSILQTAEILMSGQDLAGNELAGAPDFYLGACVTPVYDPVEVQLIKMRKKIKAG
AKFFQTQGVFDIDVMRTFKEETKDMDCKILAGIIPLKSAGMAKFMNRCVPGIAVPDALIE
RLTGAEDKVAEGITIAGEFIAQLKEEGLCDGAHIMAIGAEENVVKIMDKAGL
>L7JK78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnaporthe oryzae (strain P131)|TrEMBL
MHIRDMLAETEKTGKPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVTQAQTYFGLETCMHLTCTDMGVEKVNDALSKAYKAGCTNILALRGDPPRDKEK
WEAAQDGFNYAKDLVSHIRKTYGDHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGRVRERGITVPIIPGIMPIATYASFLRRANHMQARIPEEWLQRL
EPIKTDDAAVRIVGRQLVVELCRKILAAGIHHLHFYTMNLAQSTALILEDLDWLPSPNKP
LKHALPWKQSLGLGRREEDVRPIFWRNRNKSYVMRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLLGTNEQNRKKFGEPKSVKDIATLFVRYVQKEVDTLPWSESPLDAEAEQIRDDLID
LNLRGLITINSQPAVNGVRSTHPIHGWGPPNGYVYQKAYLELLVHPAIFEQLKERIHDHP
DLTYYAVTKSGNLHTNATYEGPNAVTWGVFPGKEIVQPTVVENISFLAWKDEAFQLGMEW
ARCHDQNTPSRILIQSMMQEWYLVNIVNNDFHAPRTIFDTLKGLTVPDIDTEIVPPALPT
AVPEAAAINGERNGERNGAQANGATAAVTAS
>A0A3S9SWP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacter fermentans|TrEMBL
MGERIIDVIHKKGITLSFEVFPPKKSQDRDLSIIFGTIEKLVDLKPDFISVTYGAGGGNK
SRASEISQFIQTTTNSIALAHLTCVGYLKKDIKEILDKFYSIGVRNILALRGDIPAGVTF
PHDAWQDFQYAKDLIQLIKEDGRFCIGAAAYPEGHVQCKDLKKTIKHMKAKIEAGADFFI
TQLFFENELFYKFMDMVESAGITAPVIPGIMPVLRAKQIKRIVELTGASIPVKLNRLLEK
YENKPEEMEKAGIEYALAQVEDLIETGVKGIHLYTMNKARQACEIVKKAGLR
>A0A2E4HLD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium|TrEMBL
MKYPHRFFFIFILYIGVLDLNSQFIKNISSSHSTISIEFFPPKSEDARLSLLEEVKKINS
LVEVCFFSVTYGAGGTTQKGTLDLVTKLSKIYEERVVAHLTCIGATMNELTELIKIYKEN
NMFHILALRGDIPEDFPENKLISRDFKYAIDLLRWLRSIGGFSSIGVACYPEGHPETSNF
EKDFQFFSEKVSAGADYAISQFFFEPKVWELFLENCSRKNISIPLIPGILPIRNIEQTIR
FAKRCGASVPDKVVKKLLRFKNDISSFNQLSADLTSELILSLENLGVRHFHIYSLNRSNL
INLISERLGWKKSFNS
>A0A1B7MLM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopogon vinicolor AM-OR11-026|TrEMBL
MKLSDKIAAYNLPHPFYTFEFFPPRTDQGFENLIPRISRLSTLNPLAISVTWGAGGSTRD
RSIDLAGLTQADYGIDTVLHLTCTNMLPGMVDDALRAAKVRGIQNILALRGDPPRGTEHW
APVDSQFTCGVDLVRYIRSSPEFSSQFCIGVAAYPEGHPDHETDEDGGLDVLKKKVDGGA
DFIVTQLFYDADRFLKWVDKVREKGITVPIIPGIMPIQTYSSFLRLIKLCGVKVPPSIMA
ALEPIRHDDKLVKDYGVGLAVDIIQNITSTGKIKGIHLCTLNLEKSVQLVIEKLQWAGGS
PEMKNKLIADAPGRMIHAQLSSSSDLVIDPTTAANTAANVLTFKQTLDPDPGRGEVNNAA
TWDDFPNGRFGDYKSPAFGAQDQWGGTGFSQYKGLSEWGHPKTTEDLTSLFLRYLHSEVS
SSPFSSLPLSSESLTILPYLERLTKRGWWTVCSQPTVDGTPSTDEVFGWGPRGGYVFQKG
FVEFFVEEHVLERIEEKIAAEGRGWVHYFAGNLQGECRSNVPDDGRNAVTWGMFPGQEIA
QTTIIERESFLTWKDEAFTIWAEWASCYPPGSEESELLDAVRKKRWLVNIVHHDYKKSDA
LWTFLLDGELPL
>D4HUG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia amylovora (strain CFBP1430)|TrEMBL
MSFFHANQREALNQSLAEISGQINVSFEFFPPRTGEMEDILWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELRSIAEDYWHNGIRHIVALRGD
LPPGGGQPEMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRVPGWMTSMFA
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPGLALAA
S
>A0A0X8E209|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microterricola viridarii|TrEMBL
MAHHHTTPGLDAQPASLPPVSFELFPPRTDAAALALGRTIDRLAEADPAFISVTYGAGGS
SRDRSLTVLRYILEHTAVEPMAHLTCIGSSYAEANSLVRQFLDAGITSFLALRGDPPSGV
TGPAELGDLGSAAELVQLIHRVQEEREPFSQQRMPGVPQGSRIARRRRPERVAVAAFPNG
HPRARGTSADVDSLLAKQVAGATLAITQLFFHADDYLGFVERARAAGVTIDIVPGLMPAT
SPARLARIAELTGEEIPAELEIALEVEPSEQGQHEIGVDYIAQLAREVLAGGAPGLHLYT
FNQHRAVLGVLERLGRMPAVAGR
>A0A3C1JWS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVIDTIKKSKSALFTFELLPPLKGHTIQEIYDTIDPLIEFNPAYINITYHQQEVIYKTR
TDGFLEKRVIRKRPGTVAIAAAIQNKYKITVVPHMICGGFTKEETEDALIDFHFLGINNL
LVLRGDPLKGARLFIAEKGGHSHSSELIEQIMNLNKGKYLNEDLIDAMPTDFSVGVAGYP
EKHVEAPNIDMDLEYLKLKVDKGAEYIVTQMFFENQTFYRFVDKCRKIEINVPIIPGIKP
VSTLNDIALLPQTFHIDLPNDLIREIKKCKTNKDVRQVGVEWATNQSKELIKSGVPGIHY
YTLDQSDNIKKIAQAIF
>C5P4Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccidioides posadasii (strain C735)|TrEMBL
MEKISNKIAALPEDADYFSLEFFPPKTQMGSANLQARLERMSQALRPLFVTVTWGAGGTT
ATKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDSALDEAKALGIRNILALRGDPPRSDE
YNLDGEDDSNKEFTYAVDLVRYIRKKHSDYFCIGVAAYPEGHSDESHPGVQDPVRDLPYL
VEKTKAGADFIMTQLTYDLEAYKRFESMLRNHESGVFKTIPIIPGLMPIQSYPRLTRITK
LSHVRVPPEMLSRIEACKKDDEAVKKVGVDILSELVEGIKTIPGTGPRGLHFYTLNLEKS
VSFILERCNLIPPSSEASSDTDSDSVFASGNLQNGLGTAADKPPLISRRRASSLNSQPHN
RVIVDRADISSQSSITHEASAQGAGMPALNPPHRNTALQISEGMGALGREATWDDFPNGR
WGDARSPAFGEIDGYGPSLHVTANVARRLWGYPTTREDINNIFRQHVSGGLHAVPWSEGG
AAEETGGLSPETITIRPYLLSLIEKRGWWTLASQPAVSGVRSDHPIFGWGPPGEGFVFQK
AFVEFFCSKDDYRSHLKPLLQRYGHDEFAWFATNAAGDFESSTSSSIPVPTGPVDAVFDD
MDSFPSSNSGGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWDEWRRIFPRGSPT
EKLLNRVKEDTWLVCVIGQRFGAGGDPGKDVMEEGKLLWKVLAGENVSLQS
>A4N3P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae R3021|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DNDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>W1F4Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli ISC7|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEIYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4R5AIW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiangella aurantiaca|TrEMBL
MALGLPSTMPGGARTIRELLAAGGRSFSFEFFPPKSEQGEITFWQTMRELERLQPTFVSV
TYGAGGTTRDKTVRITEGVARDTTLTVVGHLAAVSHSVAELRNVIGQYADAGVRNFLALR
GDPPGNPRGEWVKHPEGFEFAEDLVRLIRAHGDFCVGVAAFPDKHPRSPDLETDARFLAR
KFQAGADYAITQMFFHADDYLRLRDRVAAAGGEAPIIPGIMPVTNLRQIQRFAELTAADF
PAPLAQRLLAVEDDPEAVRAIGVEVATELCERLLAEGVPGLHFITLNKSTATREIYQNLG
VGALS
>A0A1C5IN24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora zamorensis|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTDAGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATDTTLLPMAHLTAVDHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWIRHPEGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAQFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGVEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARV
>A0A562JU57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus oceanisediminis|TrEMBL
MNFLDKLKNEFIIADGAMGTLLYSYGTDSCFEELNLSQSEQIQHIHEAYINAGAGLVQTN
TYAANYLKLQRYGLEDSVKEINSAAARIAKKASNGKAYVAGTIGGNRGIKPSMVSLEEIK
RSFREQLYCLLLEGVDSILLETYYDLEELETVLAIARKETDLPIIAQVSLQEAGVLQDQT
PIAEAFSRLEGIGADVVGLNCRLGPHHMLKTLESVPLPKQAFLSAYPNASIPAYTDGKFH
YEGDADYFRQSARDFRNQGVRLLGGCCGTTPAHIKAFADELKGLAPLEEKEVKAKKEIIV
SEKPSPSRDLPPLQEIVKERPSVIVELDPPRKLDTTRFFEGAKALKEAGIDSITLADNSL
ASPRVCNSALGYLVKQQTGLRPLVHVTCRDRNIIGLQSHLMGLHALGLNDILAVTGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSVSGKDLGQKAAFSVAGAFNPNVRSLEKAVA
RLEKKIDHGADYFISQPVFSEEKLLEVHEAVRHLKAPVYIGLMPLTGSRNAEFLHNEVPG
IKIADSIRDRMAALKDDPVQAGHEGIAIAKSLIDAAAELFNGIYLITPFMRYEMSVELSN
YTREKTERLSRRKQHA
>A0A6M1UHN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium SGD-2|TrEMBL
MDRLRAPRGARIPFSVEFSPPRDADAEARLWRAVREFERLGPAFVSMTYGAGGSTRDRTV
RVTGQLAQETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWTR
HPQGLEYAEELVRLVRDLGDFHVGVASFPEAHHRSPDLEHDTRYLVHKLRAGAEYSITQM
FFDVEDYLRLRDRVVAYDPEQGAKPIIPEIMPITSLRTARRSLELSGSKLPATLEERLVR
AAGNGPEEDRAAVREVGIDVATEMAERLIAEGAPCLHFITLNFARATREVLARLGIAVPT
AV
>E2PZT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces clavuligerus|TrEMBL
MALGTPSTRTDRARTVRGMLATGRTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTREGTVRATEQIASDTTLTPVAHLTAVNHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPEGVRYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVA
KCRAGADYAITQMFFQPQDYVRLRDRVAAAGCETPIIPEIMPITSVKQLERFAQLSNAQV
PAELKERILRVKDDAAAVRSLGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYENLG
LHKQP
>A0A3S3UE65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmobacter intermedius|TrEMBL
MSAPRISFEFFPPRSLDASFRLWETMKMLAPLKPGFVSVTYGAGGTTRQLTHEAVKAIGT
HFGVDVAAHLTCVDATREETLAIANSYAEAGVNQIVALRGDPPKGAERFTAHPEGFADSV
ELIEALAATGKFNLRVGAYPEPHPEAADDLADVRWLKRKFEAGADSAITQFFFEAETFLR
FRDKCAKEGITKLIIPGILPIENWEGTKRFAARCAAQVPAHLDEAFTKANAEGREAELSV
QVCADLCRRLMAEGVEDFQFYTLNRPHLTLAVCAEFGIHPEGQAAA
>H2JWV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces hygroscopicus subsp. jinggangensis (strain 5008)|TrEMBL
MSDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVKE
TQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVPHP
RGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFF
QPESYLRLRDRVAVAGCETPVIPEVLPVTSVKMLERLPKLSNAHVPDALKERILTAKDDP
AAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>A0A1C4X3R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora purpureochromogenes|TrEMBL
MALGLPSVLPNPQPAIGELIRERQPTFSFEFFPPKTPEGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVR
GDPPGDPGGEWVRHPKGVLYAEELVRLVRDAGDFSVGVAAFPYKHPRSTDVASDTAYFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFERVADDPEAVRRLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWRSLQ
AGARV
>A0A2E2F630|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nioella sp|TrEMBL
MTLPTPRVSFEFFPPQSLEASFRLWDTLNTLAPLGPEFVSVTYGAGGTTRDLTHDAVKTI
HGHTGVPVAAHLTCVDASRAETLEIADSYAAAGVTQIVALRGDPPKGATGFAAHPDGFAS
SVELVAALAETDKFDIRVGAYPDPHPEAADMAACVDFLKAKIDAGATSAITQFFFEAETF
FRFRDACAAAGITAPIIPGILPITNWTKVRRFATTCGAHIPDWLEDAFSTAIRDGREELL
STALCTELCSDLIEGGVADLHFYTLNSPDLTRTICAALGVTPQVALSQVA
>A0A1E4GKU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterium sp. SCN 64-44|TrEMBL
MLEDSFRASRQVAGQRPDLQISFEFFPPKTDVMEEKFWDSVNKLAPLKPRFVSVTYGAGG
STRERTLRMVSRIKAETGVDAAAHLTCVGATREEVDGVVRGYRDAGINRIVALRGDPPEG
VGQPFTPHPQGYQNAADLVAGLRRIGNFDISVAAYPEKHPQSPDWAYEIDNLKRKIDAGA
DRAITQMFFSNSHYLRYLERARAAGITAPIVPGIQPIHSFKQIASFAGRCGASIPGWLAE
RFEGLEDEPETHALVASAVAAEQVTELLDEGVTEFHIYTHNRSPLALALARILGRRAA
>A0A7K6RS04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhynochetos jubatus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTRDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A1Q6U2G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Melainabacteria bacterium 35_41|TrEMBL
MKLREIYNNNKTVISFEVFPPKDDEAKLLEEITKLNKYNPAFISLTCGAGGKENKSFELL
KDIQNSGINVMPHFTCITSSKKSVEEGLKEIENSGIENILALRGDIPENPELRHYDFNYA
NELVKYIKAKTNLSIGVAGYPEGHVESPDIKSDIINLKKKVEAGADAIFTQLFFDNNKFF
EYIQLVRNEGINIPIIAGIMPIKTYKQIVKMTSLARVTIPENLQTKINKYKEDSKSMTEL
GIEYASKQCEELINNNVTGLHFFTLNKSYSTSQILNNIL
>A0A2N0FXN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium MAR_2009_75|TrEMBL
MKITDHINNAKGKTLFSFEIIPPVKGKNIQELYNNIDPLMEFRPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYEVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNI
MALRGDAMREEQYFKPTKGGHNYAVDLVKQVHELNCGNYLHDTVETDNCADFCIGVAGYP
EKHLEAPSLKSDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVEAAKAMGIDVPIIPGIKP
IAVKRHLQLLPQVFKIDLPQDLIDAVDACSTNKEVRQVGVEWCIQQSKELKDAGVPVLHY
YSMGKSDNIKAIADKLF
>A0A2W0G3U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae complex sp|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A3R9ATZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia sp. 198|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRSGEMEQTLWRSIDRLGSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRSELRAIAQDYWDSGIRHIVALRGD
LPAGGGKPEMYGADLVALLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVIAGIDVEIVPGILPVSNFKQLRHFATLTNVRVPGWMTSMFA
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVAVPA
>A0A1F8X8B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium GWA2_55_82|TrEMBL
MEVNLRLRDELESGRFVITAEICPPRGTDVASFIEKARLLRGKVAAANVTDNQRAVMRLS
SLACSVLLLNEGIDPVFQVTCRDRNRLAIQSDILGAWVLGVKNVLALTGDHVAFGDHREA
KAVFDIDSVQLVGVINTLNQGRNMKETELRGKTGFYIGAVVAPEADPWEPEEIKFEKKLA
SGATFFQTQAIFDMDRFKRFFEKAEKTGAKVLGGILLLKSAKMAHYLNNNVPGVTVPQGL
IDEIEAAPDQLKKGIEIASRQVRELKGFSHGAHIMAIGQEESVVNIIEGA
>A0A8F4FPD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquihabitans sp. G128|TrEMBL
MTRIADLLAKGTTWSFEFFPPKTPEGLVAFDAAVNDLSALEPSYVSVTYGALGATRDTTR
DLVLRVNREQSFPAMPHLTCVGHTRAELVELLESYREGGIENILALAGDPPADGSDPGGD
FTYATELIELVREVGDFSVGVAAFPELHPRSPDRETDRRLLAEKLALADFGMTQFFFDAE
HYRRLVDELADLGSTTPVIPGVMPLVNVAGTRRMAAMNGSEIPTWLQERLDAVDGDPEAT
RRLGVEVATGLVADLLELGVPGVHLYALNRANSIEEIYAGLGLKR
>A0A257B1K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloracidobacterium sp. CP2_5A|TrEMBL
MRALKPFRELLAAGGIHVFDGAMGTLLYAKGVYVNRCYDEISLSNPALVQEVHREYVKSG
AEIVQTNTFGANRPKLEAHGFQDRVQEINYKAAKLAREAVGPQVYVAGSIGPLGIRIEPW
GPTSFEEAKAFFREQAEALLDGGVDLIVLETFTDLTEIRQALAAVKELSPDTPVVAQMTV
GEDGATGYGTASETFAKRLDEWGADVIGLNCSVGPKPMLEAIERVAALTEKPLSAQPNAG
MPQDLHGRKIYLCSPEYMAKYARRLIQAGVRLIGGCCGTTPEHIKTLAAAVRALSPTKRV
EPVISVAEDKLPDVRVTPPEEKSRFARKVARGEFVTSVEIVPPRGCDPTKMLEGVRLLKE
AGVDAVNVPDGPRAQSRMGAIATSLIIEQRVGIETVTHYCCRDRNLLGMTSDLLGAAGLG
LRNILIITGDPPKMGPYPDATAVFDIDSIGLTNMVKRLNLGLDLGGNAIGQPTSYFIGVG
VNPCAVDLDYEIRRFEYKVEAGAEFAITQPVFDVARLRAFLKRIEHCRIPIIAGIWPLTS
YRNAEFLSNEVPGVSVSPEILERMRGANASPEAGQREGLAIAREMLAEARDLVQGVQVSA
PFGRVAYALEVFAALE
>N8TRJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii NIPH 715|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHKVAGIVITPHMLRVLAQEKQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVKT
KNELVPELAYYSRQLSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASFWENAPAAKA
LLKTEFISKQGIVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A849EX67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatitalea sp|TrEMBL
MLRIFQSDLHDTDHFVVTLELVPGREAMGRTVDTVMGIARDAFADGRVSAVSITDNPGGN
PSLSPDVLGYEIFNIGMDVIVHFTCRDMNRVGMESRALQLAHMGMKNILALSGDYAGQGF
GGQGAPVFDLDSVQLQIMFEMLSERLEAAGDPDSFFAGCAVSPFKQTEAECFAQYAKLCR
KAAAGARFLITQLGYDARKFYELMQIQRHMRFALPSLGSVYVLNPKSAAIMNSGRVPGAV
VADKLLRRVRQEWRDKAAGRDAAVERAARLAAVLKGLGYRGIHIGGIHGSFDMAGRILDR
LAHIEKDWLGFVTEFNFPQPGGFYAFAHEFGADPAPPAFN
>A0A1W2H5V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquiflexum balticum DSM 16537|TrEMBL
MKITEYIDQAEKTLFSFEILPPLKGQSLKELLVGIEPLMEFKPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFHVEAVPHLLCGGFTKEETENALIDLNFIGVQNV
LALRGDAPKNEGKFVAEPHGHEYTKDLVAQIYGMNHGRYLHEETETGFHTDFCVGVGGYP
EKHFEAPSLKFDLKHLKEKIDAGAEYIVTQMFFDNQKFFEFEKKVRDLGITVPIIPGLKP
ITTLGQISMLPRTFFLDLPDPLMDELEKCKTNADVKQVGIDWAIQQSKELVANGTKVLHY
YTMSKADATYRIAKEVF
>G1UT54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp. 6_1_46AFAA|TrEMBL
MQIGTLIQAAKAPFFSLEFFPPSDEAQLPGFYATVEQLRALDPLFVSVTYGAGGARQHST
LAVTAELARRGFTTMAHLTCVGAEPGNIAAFLKELRAAGVDNVLALRGDPPKTGNWDWKQ
SYFQHAADLVAFTREHEPDMGIGVAAYPAPHPESRSFALDRRYTEEKLRAGAGFAVSQLF
FDVREYEALVEDLRAKGLNVPVVPGILPIQSFDSLRRVLSLCGANIPGKLYLSLEEAHRK
GGAEAVRDAGLDFAVRQICQLLECGAPGIHLYTLNKGDLCLQIAEEVGGM
>W6QWY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas pseudoalcaligenes (strain CECT 5344)|TrEMBL
MDAVRTSIFQTPSLETTAGGALRFAYMASHLPPNTSVNIAFIDAESAKERIVAIDVLRSS
GLTPRPIVSARRFTSEGALRSFLHQAVQIKGVRDLFLVGGDPAVPRGPFRDSLDVINGSY
LDETNISAIGIAGYPEGHPRIEGAILLDSLQRKVEALKAKGLHVEITTQLSFDALAVIAW
IQRVRGIGIKAPIRIGIPSPAGVSGILKFAKLCRVRTSVELLQRYGWETTSLLNSAGPDR
FLTELLESTERLELGPLSLHLYPLGNLEKALQWFNGWEEKSRWLH
>A0A396SFA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas jilinensis|TrEMBL
MSTHNKAPVSFEFFPTKTDAGHEKLIATAHVLAAHNPEFFSVTYGAGGSTRDRTLNTVLQ
LDGDVKVPTAPHLSCVGDSKDDLRSLLNQYRDAGIKRIVALRGDLPSGMGQASGELRYAN
ELVEFIRTETGDHFTIEVAAYPEAHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FHFVDRVRQAGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSDSIVA
FGTDVISDMCQRLLDGGAPGLHFYTLNQAEPSLAVWRNLNK
>A0A2N9D4E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. fragariae|TrEMBL
MTDPDTPSLASTITEAYSLEVSAKHIAGLAAAAPRIMRGATIAIPYLPNQDDDARLAAAR
MVRTLGFQPMPHLSARRIASREQLHAFVSRAVDDAGVERCLVIAGDPPAPLGPFPDSLSL
IDTGIFERSGIRTIAVAGHPEGHPSMPAADRWEVLQRKCRSIAERGMAPLIVTQFAFDAD
IVLTWLQALRAHGIAYPVRVGVPGPAGVAVLARYAASCGVGACASMLSKYGISLGKLLGT
AGPDRFVERLATGLTDAHGEVRMHFYPFGGIAQTVAWVEQYRSRSARV
>A0A6I6D5E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Guyparkeria halophila|TrEMBL
MSIPVSCEFFPPKSDEGEAKLREVYQTLARDIRPEYFSVTFGAGGSTQTRTFETVREIQR
DSGVPAAPHLSCIGSSREGIAAILDDYREQDIRRIVALRGDLPSGMQDPGDFRYANELVA
FIREHSGDWFHVEVAAYPEIHPQAPNAEADLANFKRKVDAGADAAITQYFYSIEAYRRFL
DDCERLNIDVPIVPGVMPITNYQQLARFSDMCGADIPRWLRKRLEGFGDDLEGLRAFGHD
VVTDLCRELVDAGAPGIHFYAMNRSGPVIRLCEDAGLIGD
>A0A1C0XC17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia pickettii|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRGILNTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGEAFHIEVAAYPEYHPQSRSARHDLENFARKVKAGADSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A6N1CI87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas bijieensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGDHFHVEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A0Q4QNB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. Leaf70|TrEMBL
MTALSFEFYPPKTDDQRAQLDRTASRLKAHAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLQAAPHLSCVGGTREEIRELLKLYRAIGVKRIVALRGDLPSGMGFPGDLRYASELIAFI
RAEQGDAFRIEVGAYPETHPQASDALADLRHFKAKIDAGADAAITQYFYNADAYFHFVDA
TRRLGVDVPIIPGVMPISNFSQLRRFSEQCGAEIPRWIAKRMQAYGDDADSVRAFGADVV
AALCERLIAGGAPSLHFYTLNLARPTSAVLQRIGRG
>A0A2N4TV17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia pickettii|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSGESIRGILNTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGEAFHIEVAAYPEYHPQSRSARHDLENFARKVKAGADSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A086ZRJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium boum|TrEMBL
MHQPMFSIEVFPPKRNAPVGTIYDTLDGLQGLNPDFISVTYGTGKSSDRTATARIANTIR
KEYDIPAVAHLTAQYTTREQVDEALDMFKQAGVSAVLALRGDPVPGREPEGAFEHASDLV
AYIREHDPDMTIFGACYPECHPQATDLDEDIRNLKIKVDAGASHLISQLFYDNADFYHFL
DKARAAGIDVPIEAGIMPVTNAKQIRRMVRMCSSRVPLPLESLLDKWGDDPKTLKQAGVI
YASNQIADLVAHGVDGVHLYSMNKPAVTRQIWHNVEDLFSPAQTGTDFA
>A0A1L8CUE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carboxydothermus pertinax|TrEMBL
MITESRLEKLFTDGHFVVTAEIGPPKNSNGEVVRKHARNLKNYIDGANLTDNQTAVVRLS
SIAAGYHVLSEGLDPIIQMTCRDRNRIGLQSDLLGAYSLGIRNVLALTGDHQSFGNHPTS
KNVYDLDSIQLIRTIKKMRDEKQFLSGEAIKEHEPRFFIGAVENPFGDPFEFRVLRLEKK
IEAGAQFIQTQCIFDMERFERFMEMVRERGLHERAYILAGITPLKSAKAAKYMKNVAGMI
MPDHIIERMEKAEDQKEEGVKIAVEMIEHLKAVKGVAGVHIMAIAWEDIVPVIVERAGLL
PRPEV
>A0A0Q4QED7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. Leaf70|TrEMBL
MPGLARPIIDGYSLEVSARSIPALAAVAPRMAPGSTMFIPNLPGEDDDARLSAAAAVRGL
GFEPMLHVPARRIASLAELESFVARAVAEAGAERCFVIAGDSSRPKGPFPDSASLIETGV
FERAGIKFLGVGGHPEGHPVMGEATRWEVLARKCRSIEGRGMTPLIVTQFGFDADAVVAW
LEALRELGIEHPVRVGVPGPAGVAVLVRYAAMCGVSASASIWSKYGISIGKLLGTAGPDL
FVDRLANGLTEAHGKVNLHFFPFGGIAQSVEWAENYRARSHPGHA
>A0A2E0FRI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospina sp|TrEMBL
MKISEKLKFSSPVFSFEFFPPKDEAGFQSLFETIAKLKPADPAFVSVTYGAGGSTRSKTV
DLVGQIKNKIGIESMAHLTCVGHKKEEIVSVLDSLQNCGIENILALRGDPPKGEEQFVKP
EGGFGYANELVSFIKSKSSFCVGAACYPEGHIECVNLSQDMDNLKRKVDCGVDFLITQLF
FDNNHYFDFIDLAQREGISIPILPGIMPILNLKQSQRFTQMCGASLSADLLAKFEGFQDD
LDKVREIGIKHAIAQCRDLIKSGAPGIHFYTLNRSKATLAILENLRG
>A0A358B1F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmobacter sp|TrEMBL
MTTPRISFEFFPPQTLDASFRLWETVQMLAPLKPTFCSVTYGAGGTTRKLTHEAVTTIGK
NYGLNVAAHLTCVEATKAETLEIAEAYAAAGVREIVALRGDAPKGATRFTPHPEGFASSV
ELIEALAATGKFTLRVGAYPEPHPDAADTLADVRWLKRKIDAGASSAITQFFFEAETFLR
FRDLCAKEGITAPIIPGILPIENFAGVKKFATRCGSAVPQWLDDAFTTAKRDGREELLSV
ALCTELCDTLISEGVEDLHFYTLNRPHLSRDVCHALGITP
>A0A1F4IYU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFCSPLOWO2_02_FULL_67_64|TrEMBL
MALPLSFEFFPPKTPDGAEKLRAVRQRLYALKPEFCSVTFGAGGSTQDGTLQAVTEIMAE
GCSAAPHLSCIGQSRESIRERLAAYAGAGIHRLVALRGDLPSGYGLGGEFRYASDLVAFV
RAETGDQFHIEVAAYPETHPQAKSPQADLDAFVAKVRAGANSGITQYFFNSDAYFRYMDD
LRQQGVDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRMRLQAYGDDTASIKAFGLDVV
SDLCDRLHRAGVPGLHFYTMNQSAATVEIVQRLRLS
>A0A3T0K5U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia sp. ICG0124|TrEMBL
MTSRLTIPDNTQAPPAERHGNVGHLERVLRSGQFAVTAELAPPDSADPRDVHARAQLFAG
HVDAMNATDGSGANCHMSSVAMCALLAREGHETVMQISCRDRNRIAIQGDVLGASALGIR
NLLCLTGDGVQVGDHPEAKPVFDLDSLSLLEIVAGLRDKHAFASGRSLTSAPQVFLGAAA
NPFAPPFAFRPHRLAKKIAAGAQFIQTQYCFDLPRFQDFMHRARDLGLVEKCFILPGVGP
LASARTAEWMRRHVPGVHIPDEVIERLKGAKNQKAEGRDICIEMIQQLREIEGVSGVHIM
AHRQEASVPEIIQRAGILGERMP
>A0A4R4YZ32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora elongata|TrEMBL
MTRVIDRLRPGKTVFSVEFFPAKTDEEERQLWRAIRELEPLDPAYVSVTYGAGGSSRDRT
VRTTGRIAGDTTLLPVAHLTGVNHSIAELRHVIGSYAAEGITNVLAIRGDPPGDPMGEWI
PHPEGITYADELVRLVRECGDFSVGVAAFPHLHPRSVDLESDTRHMVNKLRAGADFSVAQ
MFLEPEYFLRLRDRLAQHGCDQPLLPGIMPITTPRVLGMTTQLSNMTIPDEVSAALDPLR
DDAAGFRAAGLEITTRLCEKLIAEGVPALHFYSLNRAKATREVVANLGLADGVLKAA
>A0A2P5T281|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pantoea edessiphila|TrEMBL
MNSYYTNQQERLNKNRFELNKKFNISFEFFPPRTKEMEKTLWNSINFLSKLKPKFVSVTY
GANSGEKKLTYSVTKNIKNRIGLEAVPHMTCINSTRDELRNIAYKYWHNGIHKIVALRGD
VNKNNNIKQKMYCCDLVSLLKEVGDFDISVAAYPEVHPEAKNAQADLINLKYKIDAGANR
AITQFFFNIENYLRFRDRCVAIGIDVEIVPGILPVSNFKQLKNFAKISKVHIPEWMYKMF
EGLDNDPETCKMIGAHISINMVDILSREGVKDFHFYTLNRHEMSYSICHALGIKPI
>I0I430|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1)|TrEMBL
MLRSGRFAVTAELNPPDSADPQEVYDAALVLSGVCDGINAVDASGANCHMSSVAICALLT
RAGYEPVYQVSCRDRNRIAIQGDLLGAAAMGVRNVLCITGDDVTVGDQPEAKRVFDLDSI
QLLHTARIMRDFGVFLSGRKLTQPPSFFLGAVENPFAPPFDWRPHRLAKKVAAGAEFIQT
QYCFDVSRFCTFMQRVRDLGLHEKCYILVGVGPLRSVGAAEFMRARVPGVYIPDAVIERL
KGVPKSQQRAEGKRICIEIIQQVREIEGVAGVHIMAYRQEELVAEIVEEAGLLPRPFRND
APPLAHRRHRSARHLPNP
>A0A7C1E8B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
NHGMDVGEKRIGEPTAFFTGVGLDPNSINPEKEIDRLRAKREAGAEFVITQPVFDIPSLE
TFLEKADHGGLYLIAGIWPLVSLRNAEFMKNEVPGVYVPDAVISYMAKYDTKEDQLKAGL
EIARMMVDAVKPLASGIQVSAPFGKYRLAIDVADSLLQ
>A0A256ZIJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon ex4484_135|TrEMBL
MAEKPVYSLFMKNLRAGKFVYTGEAEPHKTTDISDLIESFKALKGYVIAINVTDNPTAYA
YISSLVASYLIQRETGIEAIYQVTCRDRNRLAITSDLLGAYALGIRNVLALTGDHPCVGD
NPQAKPVFDLDSTTLLYLIRRMVDEGVDLAGNKIEHPPKFHVGIAANPNADPIEPELLKI
ERKVSLGAEFIQTQCIYDIEVAKAFLKEAERWKIPVLIGITPFKSVGMMKYMIQYVPGIK
VPKEIQERIIEAKKRGGKEAVYEENIEIFTEMIKELKRTTRLAGCHMMAVGFEWIVPKII
ERVEGGRPSYIEAL
>A0A8B6QJX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYLDKTQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHLESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINSNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>A0A0B5APC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jeotgalibacillus malaysiensis|TrEMBL
MNLLEEMKQRILIGDGAMGTLLYSYGSDQCFEELNLSHAEHIQQIHQAYIDAGADVIQTN
TYGANYHKLERYGLEEKVKEINTAAVKNAKAAAKENTFILGTIGGIRSFRPQSIDLNEIK
RTFREQLYCLLLEGVDGLLFETYYDFEELAAVIEIARKETDLPIIAHISVQEPDVMQNGK
PVAEALLELEQLGADVVGLNCRQGPFHMIKSLEQVPLPEKAYLSCYPNASLPSYSEGALQ
YSNNAEYFGEVAPQFREQGVRLLGGCCGTTPDHVRAFSQALKGLAPITEKRVEKAEKIVV
QSRQRDLPEPLTDIVRDRKSVIVELDPPKKLYTDKFIEGAKALGAAGADAVTLADNSLAS
PRVSNESLGYLIKQQGVRPLVHLTCRDRNLIGLQSHLMGLHTLGLHDILAVTGDPTKVGD
FPGAASVYDVSSFELIEMIQQLNNGMSMSGKDLGEKASFTIGAAFNPNVRSVERAVQRLE
KKITAGADYFMSQPVFSEEKLIQTAEAVKDLGKPVYIGLMPLTSSKNADFLHNEVPGIKL
TEQVRDRMAAVSGDREKSYQEGLAITKSLIDTALDLFNGIYLITPFMRYEMTAELTRYAN
EQAAKRGGNQRAHIIQ
>A0A7L1ZHK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leiothrix lutea|TrEMBL
MVNETQQSCSASSSSRSDGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDRW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKDELEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A2D5US67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidales bacterium|TrEMBL
MVIPFKEILNSGKFIVTSEIAPPKGTNLDNTIHHIDLLKDKVDALNATDNQSSVMRYPSL
GLCLLIKEHGGEPILQMTCRDRNRMALESDLLFAYSRGIENVLCLTGDSMVVGDHKGAKQ
VFDLESVQLLRAIRLMESGEDLGGNELDGVVEFCAGAIVTPEAHPVEPQLLKFKKKVAAG
AEFFQTQAVYDLDNFRKFMEYAIPLNTKVLAGIVLLTSARMARFMTANLPGIFVPDNLID
EIAGAEKGMALQTGIEIAGRMIKTIQEESICDGVHIMAIGREDRVPDILAAAGL
>A0A349PQ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTQHIENAKGKPLFSFEIVPPQKGSNIKDLYENIDPLMEFKPPFIDVTTSREEYVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGIDAIPHVLCGGFTKEETEYLLVDCHYLGIDNL
VALRGDPMKGEKYFEPTKGGNTYAIDLVKQIKAMNAGQFLHEKLPVQNAPDFCIGVAGYP
EKHIEAPSLEADLKRLKEKVEAGADYIVTQMFFDNQRYFKFVEAARAIGINVPIIPGIKP
VAVKRHLQMLPQVFWLDMPQDLIHAIEQAKDNATVRQIGVEFAVQQSKELIEFGVPFVHY
YSMGKSDNIHQIASQVF
>A0A2N3EMS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HGW-Alphaproteobacteria-12|TrEMBL
MATTQKKEARDRTHVSFEFFPPKTGDMETALWRSIRRLEPLQPEFVSVTYGAGGSTRERT
HATVKRILDETTLEPVAHLTCVGAPRNEVNDVIRAYWDSGIRHIVALRGDMPELGAPYQP
HADGYQSTPELIEGIRKIADFDVIVSAYPEKHPESGSFEADIELLKRKVDAGATRAITQF
VFDTEKHVRFLEKTQKAGIEVPIVPGIMPTTNFKGTKRMAGRCGASIPKWLDEYYVGLDD
DLETRKLIAAYVAAEQVNRLRGYGFDRFHFYTLNQADLTFAICHVLGLRPQEVPVEPQTV
>B2U776|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia pickettii (strain 12J)|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRGILNTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGEAFHIEVAAYPEYHPQSRSARHDLENFARKVKSGADSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A653A3W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfatiglans sp|TrEMBL
MTSAFKKALDSGKFVVTAEAAPSKGTRLEKMQHHVEILKDKVDGLNVTDHQSSVMRYPSL
GGALLVKEHGGEPILQMTCRDRNRLALQADLLFAHSRGIRNVLCLTGDSVMLGDHKEAKG
VFDLDSSQLLAAIRTMERGKDMAGNELDGAIDMCAGAIVTPEANPIEPQLIKFEKKIEAG
AEFIQTQAVYDLDNFKRFMDYARRFPVKILAGIILLTSAPMARFMNKNVAGVVVPQALID
EMAAAPKGGALSKGIEIAGRMIRRIKEEEICDGVHIMAIGKEEVVPEIMAEAGLL
>A0A2T9JG30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter radicis|TrEMBL
MTLPPTRRVIGPVARAGERPVGAARPRVSFEFFPPKTEKMEASLWEAITRLAPLDPAFVS
VTYGAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRAEVDEVIHDYWNIGVRHIVSL
RGDPPPGEGGIGGVYVPREDGYKNATELTAALRGVAPFEVLVGVYPEKHPESPSLDHDIE
VLKAKVDAGATLGISQFFFDIDAFLRFVDKARAAGITIPIVPGIMPVTNFKGLKTMSAAC
QTSVPSWLANLFEGLDEDPETRRLIACSVAAEMCAKLQEQGFNDFHFYTLNRADLVYAIC
RVLGVRETAPAREAAA
>A0A5N7ZCB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
KFCIGVAGYPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNRKFFDFVAKCRKEGI
EVPIIPGLKPISTKKQLNQIPHRFKVDLPDELIMEVVKAADNETVKEIGIEWCIAQSREL
IAAGIPVLHYYSMGRSESIRKIAATVF
>A0A1Y5TE46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoruegeria aquimaris|TrEMBL
MTSPRISFEFFPPQTLDASFRLWETVQMLAPLAPEFVSVTYGAGGTTRDLTHDAVQTIHT
HYGLNVAAHLTCVNASRAETLEIAEAYAEAGVTEIVALRGDPPKGEGRFTPHPEGFANAC
ELVEALAATGKFKLHVGAYPEKHPEAESVQANVDWLKRKIDAGADSAITQFFFEAETFFR
FRDACEKAGIDAPIIPGILPIHSWKGVRNFATRCGTSVPAWLDDAFEKAIRDGREELLAT
ALCTELCSELIEGGVEHLQFYTLNRPHLTRDVCHALGITPDVSLEKVA
>A0A354CIF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
MKISQIHHDKKQSLSFEIFPPKKEEDFKNIDATLEILCDCRPDYISVTFGAGGSSNNNKT
IQLARKIKEKYHVEPVVHLTCLCYNRAEIDEFVRELTAEGIENILALRGDRNPDVPAKED
FAHASDLIKYLRTTTGDRFCIAGACYPDVHPETENRVDDIKNLKIKTDAGADILISQLFF
DNDTFLQFVSDCRRARIEVPIVPGIMPCINAAQIQRMVTMCGAKFPERFRKLIRKYGDNK
DALFDAGMAYCQSQIIELLASDVDGVHLYTMNNVKVAKRLTEGIKNII
>M5TUV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula sallentina SM41|TrEMBL
MTLADQYSSDGCAISFELFPPKTPQGIDALCENVERLMQFRPKYFTCTYGAGGSSQRTTL
DVLARVKEITKLPVASHLTCVGSTTEQLCDYLQKATDLGVDYIVALRGDPPKGSTEFTVT
EGGLRYANELVGLIRARFDHLGIAVAGYPEVHQEAPDAKTDLDNLKRKVDAGSDIIITQL
FYDNADFYRFRDDCVAAGINIPIVPGVLPVTNFKQAQRIAGMCKAAIPAGLAAEMGRDDS
PEHQFRVGVEHAREQTIDLLENGVPGIHYYVLNKSDAAIELLDGLQLAGQA
>A0A0B2CHP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas cannabis pv. cannabis|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTATRLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVAIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ATLCQRLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A519LHA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTEHIEKAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
IMALRGDAMKDEQYFIPKAGGNDYAIDLVKQINLLNQGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVNKAREMGITVPIIPGIK
PIAVKKHLQVLPQIFRIDLPEDLIHAVDQCKDNAAIKQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASHIF
>A0A5C7Z7H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTEHIQNANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LENGLLQKKVVKKRPGTVGICAGIQNKYEVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGHAYASELVTQISNLNKGIYLDEDLQNSTKTDFCIGVAGY
PEKHMEAPSMDSDIHFLKQKIKNGADYIITQMFFDNKKFFDFVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNYHVKQIGIEWCTQQSKELIAAGIPILH
YYSMGKAENVKAIAKEIF
>A0A7X8H404|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEYKSGSNLEKVLKAGHFAFTGECGPPQGANVEHLKEKARHLKGCVDAVNLTDNQTAVV
RMSSWAASLVLLQEGLEPNFQMVCRDRNRLAMQSDILGVYAHGIRNMLCLSGDHQKFGNH
PESKNVFDIDSMQLIHTVKTMRDEGKFLNGQDIDVPPRMFIGAAANPFAEPFDFRVYRMA
KKIAAGADFIQTQCIYNMEKFREFMKRAVDMGLHEKCYILAGVTPMKSVGMARYMANQVP
GMDVPDSLIKRLQGAGKGKVAEEGIKFAIEQIEEFKEMKGVAGVHLMAIEWEHRVPEIAE
RAGVLPRPQV
>A0A5H7D449|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Tudu|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7W0SF98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MSDRLTTSPSFEIIPLKGIEEKLSALPSGASVTVTASPAKGTKATLDLAAEVHRLGHETT
PHLSARMIADQSELNDVIDRLAGEGINRVFVVGGDADEQGKFKDALELLRAMEELGHHFQ
TVGITGYPEGHPFISGDQLRQALIDKQRHATYIATQMCFDPRAIVTWARGTRADAVQLPI
RVGIPGVVDPLKLASIARRIGVGASARFVTKNRAAVWRLLRPKTYRPTKLVRALEQEQDE
LNLAGLHIFTFNQIASTVAWLRGQR
>A0A6B1BWS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MRNDSASLSRWEEPQPAGPNPDVQELIRNSAFEIIPLNSASEAIAALPPQSRVSITASAA
KGQAATLELAEELVNRGHHAIPHFSARLIRDRGQVKDLAEWAKYVGVTTAFVIGGDATEP
GPYHDAHTFMQDLFEHDHGLDTVGVAAYPDGHPLIGEDERRHALFAKQELLAEAGMRGYC
STQMCFDPARIIAWLKGERSDGLTLPVHLGIPGAVERAKLLTIGARLGVGQSLRYLHKTR
RSMAKRLGSSAHDPSELLEALSSQLTPLGINGLHIFTFNQVETTAAWQRALLHS
>A0A831NKG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSTFQERLSKNEFVITAEVCPPKGPDTKEFLEKALLLKDHVHAFNVTDNQRSVMRFSALV
SSHLLVQAGLEPIFQISCRDRNSLALESDLLGASRLGIQNLLPLTGDPIRAGDHQLAKGV
FEFESVKLLQTIKKMNNGFDFYDNPIDGKTNFFAGAVVNPTAPNINTHLKRMEKKIEAGA
KFFQTQAVFDLKAFEVFMKEAQKFNTKIIAGILLIRSHKNVNYLRHHVPGLNIPEALKQE
LKDSSNPMQTGVEIAARQIKSLQGLCHGVHLMAIKYEEKIVDILNHVKTL
>A0A7V0JR86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSRPMKHNFVEHLNEKVMLGDGAFGTYLFEKGVDLAKNTDLLNISDPDLVYSIHEEYIRA
GSELIETNTFGANRFKMLRVGREHRVREINLKGADLACRAAGNDIFVGGSIGPTGVKFPL
ENDEVESGTVQEAFVEQMTALLEGGVDLFILETFTYLDELLLAIETAKRIAPDIPIVAQM
VYPFNGRTAIGLDALDCGRATAAAGATVVGTNCGRGVKAMLSAVERLSPLKDEVFLSAFP
NAGLPEVVEHRMVYSTPPTYMAEKVAEMVKFGVRLIGGCCGTTPAHIHEFRKHLHIKRHK
AIRVVTSVEKSSDLPEDRKDSIGRGGMIESLRSDRIPVLVEVDPPKHLDIEGVLTGARAL
ADAGADAITLAEHPMAVLRADNLSLAHRIREETGIQTVLHLTCRDRNILGLQAQIMGAHV
LGLEAILAVTGDPATSTDQPGVSGVFDVRSFGLVQMISQFNRGLNMARVSMKKRTNFSIG
AAFSYRPANPDLQISRLERKADLGAHFVMTQPIFDRDAVEAMMERTQHLNLLIFTGIFPL
ISARNADFLHNEIPGISIPREIREHLWKYEKVEDQRKAALDLTKKLIADITPFADGLYLI
SPLNKWEIPLTLVQEVRASGH
>A0A852TXM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spinactinospora alkalitolerans|TrEMBL
MLGSPTRSAAPQGLAPRPRHIRDLLAAGRPTFSFEFFPPKTPEGERKLWHVIRQLEALQP
SFVSVTYGAGGGTRDRTVDITERMATDTTLLPVAHMTAVDHSVRELRHLIGRFAGVGVSN
VLALRGDPPGDPLGEWVRHPEGLEYAEELVRLIKESGDFCVGVAAFPYKHPRSVGIDDDV
EFFVRKCRAGADYAITQMFFEADEYLRLRDRVAAKGCDVPIIPEIMPVTKLATIERSEQL
SGAPFPRHLAEEFQKAADDPDAVRRLGIEQATRLCERLLDEGAPGIHFITFNQSTATREI
YQQVAGSRVPAGAGARP
>A0A8J8NHF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halteria grandinella|TrEMBL
MASGIENILALRGDPPRDSASYDRASDAFQYAEQLVKFLKERSSRNGGRGFGIGVAGFPE
GHPDTPNRLKEMDYFKQKIDAGADYICTQLFFDNRDFYDFRERCELAGIHVPIIAGIMPV
STKNGFVRMAELSLGSRFPAKLLRAVGRAADDTATARVGLHWATEQCRDLLDNQVRGIHF
YTLNKSDATRQVFENLGVSSSRALQGQGSKD
>A0A7C6E9G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Solibacter sp|TrEMBL
MAAVKSISAWARSLTVSRAREFRRLVGERILVADGAMGTMLYARGVFINRCYDELNLSAP
ELVRAIHEEYVAAGAEILETNTFGANPFRLGSHGLADKLAAINQAAVKLAREAAGEGAFV
AGSVGPLGVRIEPLGPTSFQEARAAFRQQIAALVEAGVDLLILETFGDLSELREAIFAAR
EAAGPEMVVVAQVTVDDYGHMPDGSAPEVFATRLDEWPADVIGLNCSVGPKVMLETIEKM
MSFSRKPMSAMPNAGHPATVEGRKIYLSSPEYMAQYARRFIWAGVKIVGGCCGTTPEHIR
AIKAEARSLQPVHRHFQVTVEPPKDKAGAALPPLPLHHKSQLGAKLAAGRFVAFVEILPP
RGADASKEIAGARLCAAHGIDCINVPDGPRASARMSAQVTCQLIQQQAGIEAVLHFCCRD
RNILGIQSELLGAQAVGIRNLLCITGDPPRMGAYPTATAVFDVDSIGLVNIVRNLNRGLD
IGGNPIGSQTSFLIGVGVNPGALNFEEEMRRFEWKVEAGAEFAITQPVFDVRLLERLLKR
IERFRIPVIAGIWPLISLRNAEFMVNELRVPVPDEFLARMRRAESGERARAEGLAIAQEM
IQRVRSLVQGVQISAPFGRYEMAIRAASAIGPR
>A0A7V3KXS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTKIAQDFENRKFVVTGEIGPPKGVDLDKCLRAAENLRGKVTAINVTDMQSAVMRVGSMA
VCAKLVERGLEPIYQLTCRDRNRLALQSDLLSAWALGIRNVLCLSGDHPSLGDHFDAKPV
FDLDSVQLLKVVEMLNGGKDMADHELEGKPEFFAGAVVNPGSDPLELQLIKMEKKIEAGA
KFFQTQAIFEPEKFEKFINRVQKYKVPIIAGIVVLKSAGMARFMNANVAGISVPESIIEE
MAKTKGENRREKAVEIAARIIKQVKPLCQGVHIMSLGWEELVPKIIEEANLNG
>A0A101XTB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidibacillus ferrooxidans|TrEMBL
MATQLYQMGTPVGICYEALCLERPNAVTAVHKSYLEAGASLLETNTFGANAHGLARYGLE
GKVVEINRAAVRLARQVAGEQAYVAGTVGSVRGVRPAGPVRAELEAIYREQIEALLTEAP
DALLFETFYDLDELEIALDVARSLTVLPSIAQLSLIDLGVTRDGVALSDAFARLYDHGAS
IVGLNCRFGPSDMLRVLEKANLRATDRISVFPNAGLLSVTDGAYHYASEPEYFGEIAQSF
HAMGVRIIGGCCGTTPDHIRAMANAVAGRAPAPVKAGGNAAREGTDARRPRVAERSVLHS
DDASAGELVHEKARHTHTVIVELDPPKDLSPNVFLEGARALHAAGADAVTLADNSLAVTR
MSNMALGAMMKQMGVEPLLHMSCRDRNLIGQQSHLMGLHALGIRQVLAITGDPSRFGDFP
GATSVFDVSSFDLIRMIKQLNDGRSFTGRALDECARFTVGAAFNPHVRHLDKAIRRLERK
VEAGADFIMTQPIYDPEFFDVLADLTSHVNVPIFVGIMPLLSARNAEFLHNEVPGITLTD
DVRKRMAEAGTGAHARSVGVEIARELVDAAMKRFRGIYLITPMMRYEMTVGLVEHVARTA
RNMDQAGSTPA
>A0A661IGF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MFNTLIQKLQEDKYITLETTPTHEPVFDNIIEKIEQYNLDKKVDGFSTTDNPLAKLKYNA
LFASIKLQQKFNKPVIATMSMRDRNKIALQSDLLGANDFDVRAILALTGDPANMSDQPRA
KGVFESNSNMLLEIIQSFNNGMDYAGKPFKTAPKTIYPFSVINSYAKNMKSLEKKMNKKI
LNGTKGIITQPVYDVDNAKQLLGYFDSAKESFKDDRNKSQLILGIFPITQLRTAQFLHSH
VPGIYVPQDWIDKLTIASKISKDEERKVGMKLSSDLLKSIQEIHPKVHLMTANKFDLASE
LLD
>A0A318CNY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEERLAQRDPGYDVGRTERGFVITFELVPARASRGKAIDEILRFAGEAAAGGLISALSIT
DNAEGHPALSPMALGSEIKALGIDPIIHFSCKDKNRNLVESQLFVLDRSGLKNLLVLTGD
YPGYGFMGNAKPVFDLDSVQVLGMVSDMNRGFVLDSKAPYGGVKLAPMSFHAGCVVSPFK
RLESELIPQYLKLKRKVAAGASFVITQMGFDVRKFDELRRFMDREGLRVPLLGTVFIPTI
KLARILHRGEIPGCILPGRLLERMEQEAMSDDRGKGARLERAARLVSILRGIGYEGVHLS
GPGLKYSQVEWVIKRANEIGERWKLFTCQFLFPEEWKFWYFKEDPGTWLNRDEPNPGADA
TPSLKDSLGLGLGRLFHELAFEPGRPLFSSLRRMAGWIDGSSSQSCFTSFEYWIKKWLYD
CRCCGDCTLEEMGFLCPQSGCAKFLLNGPCGGSRDGWCEVWPGRQKCFYVRVYERLKSLG
KQERLSGLPLPPRDWILYNTSSWLNFYLGRDHHKIRMIKKFS
>A0A396KZ24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea sp. AF36-15AT|TrEMBL
MRLLDKIKDHILLMDGAMGTYYNQQYGTELEAEEANLVHPEEITAIHKAYIKAGAELIRT
NTFAVNHLMFPKQEECKRAIHAAIACARQAVAESSREVEIAASIGPIRQTVTEDDENTIK
EYQFLINSMLAEGIHIFVLETMLELKWVQPLSEYCKSQCEESVVIVQFSLNPSGYTQYGF
GMKEIIDKLCQMETVDVFGFNCGVGAAHLRKLLEKQTFPKECMLSVLPNAGYQQELRGRM
HYGDDPEYYAKQMERMIPLGINIAGGCCGTTPEHIAALKKVLGGQAPQPKEVVEENADGE
SVSNAAPTDFISKLDRGEKVFVVELDAPFDAQMDKFSKGVYALKENGVDMITVSDSPLAR
SRADAALLAVYAKRLTDISVMPHVAMRDRNLIGLRSEILGAHANGIRDFLVITGDPVGPD
NRGKITGVFDVNSIRFMEYLQHMNEEIFPDQPVYYGGALNYAGNNIRAISGRMRKKMEAG
CAYFLTQPIFSEEDVQRVIELKEMTGAKIICGLMPLVSYRNALFMKNEMPGIHVNDEILN
RYDPEMSREEAEDTAVALCLDIAEALRGAADGFYLMTPFHRVGLVNRIINAIKQGE
>A0A7C1BFU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSRQIKYKFVDQLNEKVMLGDGAFGTYLFEKGVDLSKNTDLLNLSDPDLVYSIHEEYIRA
GSELIETNTFGANRFKMIKFGREHKIREINLKGAELACRAAGNDIFVGGSIGPTGVKFPL
ENDKVDSSAVQEAFFEQMTALLEGGVDLFIIETFTYLDEILLAIETAKKVAPDIPIVAQM
IYPFRGRTAIGLDALDCGRATAAAGATVVGTNCGRGVKSMLSAVERLSLLKDTVLLSAFP
NAGLPEVIEHRMVYSTPPSYMAEKVAEMVKLGVRLIGGCCGTTPAHIHEFRQHLHIKRPK
AIGVAVSVEKASDLPEDGKDLTGRGGMIDGLKPDRIPVLVEVDPPKHLDVEGILTGAKAL
AGAGADAITLAEHPLAVLRTDNLSLAHRIRVETGIQTVLHLTCRDRNVLGLQAQIMGAHV
LGLEAILAITGDPATSTDQPGVSGVFDVRSFGLIQMISQFNRGLNMAGVSMKERTNFSIG
AAFSYRPANPDLQISRLARKADLGAHFVMTQPIFDRDAVEAMMNSTQHLNLLIFTGIFPL
ISARNADFLHNEIPGISIPTEIRKHLWKYEKVEDQRKAALDLARKLIADIISFVDGLYLI
SPLNKWEIPLTLLQELRAAGH
>A0A7V7K197|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSRLERILNSGEFAVTGELGPPKNGNAEVVREKARILKGHVDAVNITDCQTAIVRMS
SISAGLLTLAEGVEPVIQMTCRDRNRIGMQSDLLGAAALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMVRDMRDEKRFQCGEAIKNNEPRLFLGAAANPFAGPSEEVRAARLAK
KVANGADFVQTQIIYNVERFAKFMQAVRDLGLHEKVHILAGVTPPKSLGMARYMKNFVPG
MDVTDEVISRMKDAKDKEAEGINICVDVINQVREIKGVAGVHIMAIEWESAVPEIVKQAG
LATRPVFDDEPVASAVTVASGVIEVRGGAQAVTTEESDTVLAAAKAEAEKIIAAAKDEAR
QLCAGARIADAGSTGADQARIEIDDAGEEEMNEKERQMALESVRLGLGALKKAFGLSDDQ
FDALSKFAGAEAILGREPVSAAAPASAPAAPAAAKPAAAPVADQAEEAKKAAAAKAAQEA
KQAEEAKKAAEAKAAQEAKIAAEAKAAEEAKKAAEAKAAQEAKKAAEAKAAVETKKEAPK
AAAPVAGLEVATLATEKTALADRSTKLPEASYKQAYTGAIRENVLGNGASTVKVGGANTL
PFQLFEGAMPNKPVIAFDIPDLKPEEWPATLSQHFADVLDNPVAWAQKCVKSYNAEALCI
SLVSTDPNGKNRSSADAAKTAAEVINSVDVPVIVWGCGNSEKDTETLREITSVIGDKKVC
LAPLSDANYRAIGATAMAFQHPIVAASPIDVNLAKQLNILLQNLGVSLDTVLIDPSIGAL
GYGIEYTYSVMERIRLAALTQQDDKLQVPFICNLGREVWKAKECRLPSDDLIGDAERRGI
LMEAITASCMMMAGGELLIMRHPKAVALAKSMVNGLIG
>A0A7Y2NB78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MSKRRIRISEAGAAALRPLLEHPKYELIPLKNAMEQAAFLPTGATVTVTASPAKGMQATV
DLSRELLDLGFDVVPHLSARLTTDRAELESILSQLDDAGITKAFVVGGDADPPGDFYDGL
SLLEAMKEIGHGLVDIGFPAYPEGHPVIPQDALDQALHDKAPFASSMTTQMCFTPDTIVG
WLRDRRAQGIDLPAYLGIPGVAELRKLIGISARIGVGDSLKFLTKNTSLVGKLVRPGGYS
PDALLIGMADAIAEPSNGIHGFHIYTFNQVESTERWRKEMLAELG
>A0A7C1MZR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSVKTPSRLEKVLDSGQLAVTSECGPPRGSDPEAITRKAEMIKEHVDAINITDNQTSVTR
LSSLASCIHLKLMGLEPILQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQTFGDSP
QGQNVFDLDSMQLIQTVRLMRDEGKFLGGDPIKRPPAMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNLDKFELWMKQARDRGLHEKVYILAGVTPFKSAGMAKYMKNRVPG
MDVPDEVVKRMAGVPKEKQAQEGINICVETIQRLKELEGVSGFHIMAIEWEEKVPEIVER
SGLYPRPKDL
>A0A509L5G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MQKCEVIFARALNALNSSPNGVGSSTMLRVFQNDLFLPEDFITTLELVPGKDSSGRSVDT
VMGIARDSFSDGGLSAVSITDNPGGNPSLSPDVLGHDIFKVGMDVIVHFTCRDLNRVGME
SRALQLSMMGMKNLLALTGDYTGKGFGGQGAPVFDLDAVNLLMMLDHLSHRFHENGDPDG
FFAGCAVSPFKYTEAECFAQYAKLCRKISAGARFIITQLGYDARKFAELITVLKQLEVNL
PVFGSIYLLTPRSARIMNKGMVPGVVVTDKLLTRVLDEWKNPKAGRVKAIERAAKLGAIL
KGLGYQGMHLGGIHKTFDVAGDVMSHMKAIQDQWQSFLPEFEYPVTNGFYVFPDDISEKL
PANSFGQQTSIPMLEKIHFRLMKSFHNRFFSFESKQARTLEKVCGWIDHHRIAEGIVTLL
ENSAKKILLGCQHCGDCGIQNLAFLCPESRCPKHTRNGACGGSSDGKCEVRTDRNCVWVR
TYRRMAYSGTCQNLLSGCVPPRMWELNQTSSWLNFHLKRDHQSVSTGLEKYCRLEDCQLS
FCEHYGKPLNPKG
>A0A7C1H048|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRENFFKNALLNPDVFSVTWELVPGRGAKETAQEKIPDLVRQAAEGGKIHALSLTDNPGG
TPAMSADFIGSEIVKFGIEPLVHFASKDKNRGAIESQLYALDRAGVRNLLVMSGDYPVFG
FQGRPAPVFDLDPIHILQLISEMNKGLEYPGIKGTIRHQASDFFAGAVVSPFKATEAEQI
AQYYKLKKKIDAGAQFIVTQLGYDARKFHEVIQFIKQCGFNLPLVGNIYILSYGAAKMMN
SNELPGSVVTDKLLAEIDQERKEPDKGEKARILRAARMFAIAKGLGYNGVHIGGHNIKYE
QVEDIIRQGEALVPQWTDLLKYFHYPMENGFYYFEYDKKSGLNQEKETNRQNAPPDAKIG
FSYGISMFFHKLMFEPGKNLYGLMKAISRKIAGSKLENIFHKLEHLTKVLIFDCKDCGDC
ALIDIAYLCPMSQCPKNQRNGACGGSYQGWCEVYPFKKQCIYVRAYFRLKKRGQEAQLEK
NIVPPCNWDLNQTSSWINFYLGKDHTSKKHDNSPAGK
>A0A1M5NVE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. CF108|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAIDLVRQINDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A0E1T1V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 53638|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3D4Z4V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MFKLKEKLEAGEFVITSEIAPPKGPDLGEFIEKAKLVQDRVVAINVTDNQRAIMRLSSLV
ASAALEREGIESIYQLACRDRNRLALQSDLLGAHAFGIRNVLPLTGDAVAQGDQKDAKPV
FEMTSVKLMALVQKLNQGLSYNDHPLNGKTEFFVGGAVDPKNIGAKAFFQKMEEKMKYGA
EFFQSQPVYDLDLVEKFFRYAEEHRVKSLIGVLLVKGPKQAAFLNSHVPGIRIPDEIIHR
FNGASEPLQVGIDFAARQIRELRPLSHGIHIMTVGREDLVPEILNRAGL
>A0A1F9A6N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_52_11|TrEMBL
MRGESRLEKVLQEGRFAVTAECGPPKGADPEAIRKKGKMLKGFVDSVNVTDNQTGVVRLS
SLAACTLLIQEGLDPVLQMVTRDRNRIALQSDILGASALGIRNILCLSGDHQSFGNQPQA
KGVFDIDSIQLVHLVRQMRDAGVILGGERLTEPPHLFVGAVENPFADPFSYRVLRLEKKV
AAGAEFIQTQCIYNIVRFKEWMGQVGDRGIHEKVYILGGVTPLKSARMAEYMSKQVAGMD
VPDEIIKRMKSVLADKQREEGIRIAVEAIEALKEMKGVRGVHIMAIDWEDVVSQLVEEAG
LIPRPNV
>A0A661PD71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSLRSKLEAGEFSLLAEIETSKGIDVLSMVANARQVKDKVTAFVVPEMSNAVMRMSALGG
AMVLQNKDMETVMQVNCRDRNQLALQADLLAAGACGIVNIIAVNGDDPSVGDHPQAKAVY
DLEPCELLQAARELNNGSDLAGNPLSGATNFLLGATANVCCEGETLEREVEEVNKKIAAG
AQYIITSPVFDLESVENLASTIDCQKKKVIPTVLLLKSVGMARYISQTQEYISIPDSIID
RIRKSSDKAGECIRIAREMIAALEAAGFGGVLISTVGWEHKLPEILL
>A0A534WCM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRITDMLRFAAERGEPVFSFEFFPPKNDAGVAALFETLLALRPLGPSFVSVTWGAGGSSR
GRTLEMVTRIKRETEIEAMAHLTCVGASRKELEEQLAVICDAGITNVLALRGDPPRGQRE
FIVHPEGLAHSTDLVQLAREVADKRGVSLCIGGACYPEGHPETRDLTKDLRHCKQKVDAG
ADFLITQLFFDNRRYFEFFGRARAAGIEVPILPGIMPITNVDQIERFTALCGAHIPPGLS
AALRARRDDPDAALQLGVAYAALQCAYLLRGGAPGVHFYTLNRSTATRAILAALRAQEPW
REA
>A0A318B6W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. 3335mG|TrEMBL
MSSKVDPFAAPLFADVAGDIDVSFEFFPPKTEKMEETLWESVQTLAPLSPRFVSVTYGAG
GSTRERTHNTVARIARETNMAAAAHLTCVEATREEIDQVADDYWNAGVRHIVALRGDPPR
AGEKYSTHPGGYENAAALVEGLRRLHPFEISVAAYPECHPDSPHAAADLDNLKRKIDAGA
TRAITQFFFEPETFLRFRDDAAAAGISAEIVPGIMPVMNYASVVRMSAMCGTDVPAWMAR
LFDGLDDHPAARQLVSATLAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGVRPMAD
AA
>A0A661R3Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
VGMAQYMAKAVPGMDVPESLIKKLRGAGKGKVAEEGIKFAVEQIQELKEMEGVAGVHLMA
IEWEHRVPEIAERAGMLPRPKV
>A0A3D5WAX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
YILARSRKKGEVLKGFVDGVNVTDNQTSVVRMSSISSCVILKGLGLNPIMQMVTRDRNRI
AIQSDILGAAALGINNILCLTGDHQKFGDHASAKNVFDMDSIQLVQTVKLMRDEGKFLGG
EELKGSPRMFIGAAENPFADPFEIRVPRLAKKVAAGVDFIQTQCIYNLPKFEKWMKLVRD
RGLHERVHILGGVTPFKSVGMANYMKKSVPGMDVPDELIERMKAAPKEKKAEEGINICIE
TIQRLREIEGIHGVHIMAIEWEEMVPEIVKRAGLFPRPHIEG
>A0A496ZHH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSLKQKLVAGEFAVLVEMEPPKGVDVSVMVANAQKVKGIVNAFVVPEMRNAVMRMSSLGS
GMILQSKGMDVVIQVNCRDRNRLALQADLLAANGCGIHNLMVVRGEDPGFGDHHQARAVH
DIDLTELLKVIQGLQNGRDMAGIELNGAPTFLVGATVDAGARDKSPELIREEMDQKREAG
AEFFITPPLFDLSTIEPFLKRVDRSETKIIPTVLLLKSLGMARYISRNVSQMFIPDALIQ
RLQKAPDKVSECIKIASEMVQTLKKEGFCGVQLSTIGWEDKLPAILKGV
>A0A523C5Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLVKDILDNNRFSFSFEFFPPKDEPGWENLFANISDLMPLKPAYVSVTYGAGGSTRDRTH
KLIVRIQQETNLTVVSHLTCVGSNRAETGEILRNYAASGVENILALRGDPPKGQTDFVHP
PDGFAYAADLVAFIKKNFPHMGVGVAGFPEGHPATPNRLLEMDYLKAKVDAGADYIVTQL
FFDNRDFYDFRDRCELSGITVPIIAGLMPITTKSGMVRMAELAAGARIPAALLRALDRAR
SDEQVEKVGVHWATEQVRDLLDNEVRGIHFYTLNHSRQALDIYQALGVEDSIQLGA
>A0A3A4RGS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MHFQELLDSKKFLVISELQPPKGTDLTEFYDYAEKMRGRIDAINVPDLQSAVMRLGSLSA
SYLLKEKGFTPICNMTCRDRNRLALQSDLLNISVLGIENIVISRGEDPSLGDHPGAKPVF
DLTPLEFISAVRELQKGYDMAKSDLHGTPKFCVGSTVNSSAQRGALDLEIKKMEEEIRAG
VDFFLTTSVFELDFFENFIRKIEYLKVPIIAGIMILKSVGMARFMNKHVEDVFVPEVLIE
RLMKSADKPKTSVEIASELINGLKPLCQGVHVIPFGWEDKVPSIIEKAGLY
>A0A1Q5R6B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. AS23.2|TrEMBL
MTDLTTPAQADGQDGHLAVKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYG
AGGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDP
PGGIGTPYSSHPDGYQSSAELVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKAKV
DAGATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRAGTTVPD
WFAAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIR
AKSAQKAA
>A0A1G7XHE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinosporangium album|TrEMBL
MIPDRVPTVREMLASGDRTFSFEFFPPKTDEGERNLWRAIRELEALSPTFVSVTYGAGGS
TRDRTVGVVERIAHSTTLTPVAHFTAVDHSVRELRHLIGRFADAGVRNILAVRGDPPGDP
MGEWLRHPEGVLYAEDLVRLIRQSGDFCVGVAAFPYKHPRSTSIESDTDYFVRKCRAGAD
YAITQMFFRAEDYLRLRDRVAAKGCDTPIIPGLMPVTQMSTIARSEQLSGAPFPDDVAKR
FEAVAHDPVAVRRLGIEHAAELSQTLLNEGAPGLHFITFNKSSATREVFQRIQPVPAKAG
>A0A101P8S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces yokosukanensis|TrEMBL
MVRHQPKLGEVIAAGDTSYSFEFFPPRNELAERRFWKALRRVETVSPAFVSITYGAGGTS
RDSTVRIAERIAAETTLTPVAHLTAVGHSRAELRNIIGQYAESGITNVLALRGDPPGDPN
GTWIPHPQGFRHAAELVEMVRSCGEFSIGVAAFPEGHPRSAGPEAELRHFVDKCRAGADY
AITQMFFRVEAYLRLRDRVAAAGCTTPIVPEIIPITDHRQLRRFAALSDAPLPTALAGRL
ERHRDDPAAVRRIGMEHAHEMCARLVAEGAPGLHFITLNRAEDALALHAAVAPDRPARHP
VGA
>A0A534P8U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIAELYRRKRPVFSFEFFPPRTDAGVDALFRALGELAVLGPDFVSVTCPLDKPRRPLTF
ALVARIQRELGLTAMAHLVTVLYARDEVRAVLEQLAREGIENLLALRG
>A0A2E5C279|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKKVKWSMEILPQNVSDLSFIPDLIQEVYITMIPGTSFNDTILAAQKIQESGKKAVPHIS
ARSLIGIKELRSCLSGLKNSGIERILLIGGGFSKPVGDFSSVMDVLKTEMFEEYGINSFD
FAGHPEGNPDDPDSDHNLLEKLKWTEKRKIPTRIVTQWTLDTEKTNNWIKSIRKNGIQNP
INIGIPGPSTIKTLLRFAKVCGVKASTEVLRKQGLNISKLMFVNKPNKIVSELKGYDQLH
L
>A0A147GGM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas parafulva|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SQVQVPAAPHLSCVGDTKAELRALLAEYKQVGIKRIVALRGDLPSGMGMASGEMRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEADLANFAHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEELLQGGAPSLHFYTLNQAEPSMAIWNNLQSSR
>A0A2D4RVY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIIEMYHNRPFVFSIEVFPPKTEEGMVNLQEKLRTFSLFKPDYISVTYGAGGGTRQNTQ
QLAGFIGNELGIEVLAHLTCVSHTRKDVSLLKEQFLSEGVENIMALRGDPPTTEKTFEPM
PGGYSYASELIEDLSRDRRFGIGAAGYPETHIDAISSQMDRYFLKQKIERGAEFVISQFF
LENQKFFSWRDQLYKEGVRIPIIPGLICAQSSSQIQRFAKMCGCIVPSQLIRNLERFEGN
AGDSLRVGLDHAEQQLKGLIREGIGGVHLYALNRSEVVNDLGPTLVGLKSRPDLKSSLEN
DGRLSF
>A0A2E2WDS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSRHRKHQPSPLYRLRHETPMKLIDLYRRKSFVFSIEVFPAKTAEGMETLKQTLGTFAKF
XPDYFSVTYGAGGGTRENTHALATHLQNKLGIETMAXLTCVSHTGQEIEVLLRRLEKSGI
ENVMALRGDPPQGSTEFRRPENAYNYACELVAAIQKRGGFGIGAAGYPEGHIENPDQDAD
RHFLVGKINAGADFIATQFFLDNSFFLRWRDQLAADGVSVPLVPGLLVPTSLKQLTRMAD
FCGISIPNKLRIQLETHHTDPEAMKQIGLEHTSRQLENLLREGIPGIHLYALNKLATVQH
LAPLLPYSSKNLLAPCAA
>A0A1J0GKI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium estertheticum subsp. estertheticum|TrEMBL
MNIKELPLIFDGAMGTYYASIKENPLSKCELANIYDRNTILNIHKEYIEAGCKAIKTNTF
GANKISLESDFNGVKDVIVKGYEIASEATKGTDVLVFADIGPIPFLETLDLWEAYKEIVD
LFLELGATHFIFETFSSDEYLPEISKYIKEKNPKAYILMELAVSPEGFTRIGISGEKFIE
KVSNISSIDACGFNCFSGPYHLLKYIKTLNIKNKTISVMPNSGYPTVINNRTFFNNTKEY
FARQMLEIAKQGVAIIGGCCGTTPEFIRETVANIEGLSPNEIVPSIKIEKIKFEKLIVEN
SLLEKIKLGKKIIAVELDPPMDTGIDFFMNSAKSLKEQGVDAITIADCPVARVRVDSSLL
ACKLKRELDITTVPHMTCRDRNINATKALLLGLSIEGVNNVLVVTGDPVPTAERDEVKAM
FSFNSAILANYITNLNETTFSSPFNICGALNVNAINFSSQLEHAKKKIENGVTMFLTQPI
LSKQAVDNLKQARRELPAKILGGIIPIVSHRNACFMNNEISGITVSDEITELYNGISKEE
ATILAIKISTDIAREIYDYVDGYYLITPFKRIDIISEIIKSIGNIGNS
>A0A7Y6GRA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces fungicidicus|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRTGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVTAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>D7CN71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophothermus lipocalidus (strain DSM 12680 / TGB-C1)|TrEMBL
MARSNLERVIIGGHFAVTAEIGPPKSCNADFVRKKARALKGYADAFNVTDNQTAIVRMSS
IAAGVIIQSEGLEAVIQMTCRDRNRIALQSDVLGAAALGIKNILCLTGDHQSFGNHPEAK
NVFDLDSIQLLYAVRNMRDHGRFICGEEMKVRPDMFIGCVENPFADPFKFRVIRLKKKVE
AGAEFVQTQCVLEMGRFREFMKMVVEQGLHERVAILAGIMPIKSAKMARYMQKNVAGMMV
SEEICRRLEEAKDVEEEAIRIAVEQVQEVREIPGVRGVHLMAVAWEEVIPEIVSRAGLYP
RP
>A0A164APE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus elgii|TrEMBL
MKPDLREALRRQVLVGDGAMGTYLYQMGFPVGISYEELNLLEPDVIMDVHRRYYEAGARL
IETNTFSANREKLSKYGLEQEMEAINRAGVELAKKAVGDDAYVIGAIGSIRAGKRKNVRT
AKVKEDFRDQIEVLVDTPVDGLLLESFYDLEEVLIALRLIRKFSELPVICQFATEGTGST
HDGILLTEAFRKLTAAGADVVGFNCRSGPNGLLRSLQRVAGMEGAPPFSVFPNAGIADYV
DGRYTYAATPEYFGETARKFVDLGARIVGGCCGTTPEHIAAMAQSLQNYAPDPGALRLLQ
EAGEGSGAGRIVTRLQPVPSPPAPEPNLAELAKERYTVIVELDPPRDLDIEKFMQGAQAL
KNAGVDALTMADNSLAVTRMSNLALGSLVKERIGMKPLIHIACRDRNMIGTQSHMMGLHA
LGIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKSLKKKANFVVG
AAFNPNVKHLDKAVQRLERKIESGADYIMTQPVYNAELIEKVYEATKHLDIPIFIGIMPL
ASGGNAEYLHNEVPGIQLSDEVRQRMNGLKGEEGRAMGVQIAKELLDAAMHYFKGIYLMT
PFLAYEMTVQLTEYVWEKAHRLDSHLYPLSK
>A0A644TKS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MTCLDWIYLCEEGGNTESRRLNPIDKVEKTFREGKGIEMENRFKQSLLDPNTLSVTWELV
PGRGAREKAQESALLAAEQAAKGGKVHALTITDNPGGNPAILADYLGQEILKLGIEPLVH
FTCKDKNRNQMESQLYALDRAEVRSLLVMTGDYTVSGFKGRPKPVFDLDPTHTLELIAQM
NEGLGIPGPKGMSYHQPSDFFAGAAVSPFKGTEAEQMVQYYKLKKKVTSGAQFIVTQLGY
DARKIHEVLQFMKLNDLNVPLVGNIYILPFGAAKIMNQNQLPGCVVTDKLLAEIDKERTA
EDKGVSARLLRAAKMYALMKGMGFAGVHIGGHNIKYEQVEYVIEKGEELSKDWLALVPEF
DYPMPNGFYYYEKDPKTGLNTTTPVNRKNLPLDAPVGVAYSGMRLMHSMLFTPGKNFFPV
MRKIYKGRKDNRKHGLEHLAKVITNDCKDCGDCAMFELAYLCPMSQCPKNQRNGACGGSY
QGWCEVYPNQKQCIYVRAYARLKKYDEEGDLDSHHIPPANWDLYQTSSWSNFFLGRDHSG
KILGIPTPEEEAKAKGADPAK
>A0A1S3AD50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erinaceus europaeus|TrEMBL
MDYPKPQVLPAGPRCSSLGLWGSGAASRTFSVPPSISRSSAMVNEPRGLGGPQPHSEGSS
SGGESSRDSSRCSTPGLDPERHERLREKMRRRMGSGDKWFSLEFFPPRTAHGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETVLHMTCCQQSRETITG
HLHKAKQLGLKNILALRGDPLGDQWEEAEGGFNYAVDLVKHIRSEFGDYFDICVAGYPKG
HPDAGSLEEDLRHLREKVSAGADFVISQLFFEADTFFHFLKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGVELAVSLCRELLASGLVPGLHF
YTLNREVATTEVLKRLGMWNEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDDFPNGRWGNSSSPAFGELRDYYLFYLKSKSPREELLKMWGEELASETSVFEVFAHYLS
GEPNQQGHRVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYDLRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWMEQWGKLYEEGSPSRKVIQHIQDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLHGPVPSKREPAAP
>A0A6B8HGL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAGLSLRADAFINAFSLEVSAKAMPALCAEADRIPCGTVISIPWLASEDDDARLAAART
VRALGFEPMPHLSARRVGSRAALERFLQRAASEARVARCLLIAGDLATPVGPFADSASII
QTGVLEQSGIKVVAIGGHPEGHPVMSSDERWQALERKCQAIEARGMAPLVVTQFAFDADT
VLAWLDALRARGITAPVLVGVPGPASIPRLMRYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVKGLTSAHGPVSPHFFPFGGVAPSLEWMAQYRRRISGTGG
>A0A081BMQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Moduliflexus flocculans|TrEMBL
MLIKELLQTGQTLLSFEFFPPKTDKGWDELFETVANLQPLHPSFVSVTYGAGGTTRANTH
RLVTRIQAEAALNVVAHLTCVGAKKEDIRQILTEYQAHGITNILALRGDPPKGQAEWSPD
GGEFLYAADLIAFIKTEFPQFGIGVAGFPEGHPQTPNRMLEIERLKAKVDAGADYITTQL
FFDNRDFYDFCERCELAGIHVPILAGIMPITTWKGMLRMAELAAGARFPAPLLRAVSRVK
DDDALVEQIGIHWATEQIRDLIDHRVRGIHLYTLNKSSASLKICQTLGIKDVEGYFSAK
>A0A7W9KC40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kutzneria kofuensis|TrEMBL
MELSCAHVLDRLTGPGPVFSVEFFPPRDEADEQRLWLAIRQLEGLEPAFMSVTYGAGGSS
RDRTIRTTGRVVQETSLLPMAHLTAVDHSVAELRNVIGWYAAVGVRNILAVRGDPPGDPM
GEWVKHPQGLSYAEELVALVKGLGDFCVGVSAFPYGHPRSEDLDTDTKYLVRKFRAGADF
AIAQLFFEAEDFLRLRDRLAKRGCDAPLLPGILPLTTVRTLRKTVELSGAPVPPSLARRL
DPLVDDPKAFRAEGIDIVTELAQRLIDEGVPGVHFYTFNMSKATTEVVERLGLVPARA
>A0A644Z7R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MRITDKIKSNGKLSFEVFPPKTDKPLEPLLETLEKLYAFKPSFISCTYGALGSNKGRNLE
VVESIQKRGVCEALSHFTCVGNSREDVLTAIAEYRSVGVENLLALRGDIPKGAKKVTGDF
QHANELIEFILQNEPSLCIAAACYPEKHLLADSLERDIDMLLKKQDAGASFLMTQLCYSV
ENYLRFLEAARKRGVTLPIIAGILPILKPDGLVRMTLSNGCSIPKEVAALVGRYGEDEQA
FRAAGHEYIVELVQTFMKADVAGIHLYTLNHFEDVAALVRDTGLSDAQ
>A0A139P3F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLTIPTIAHLPAIYLTKEKVAETIADLDQVGVQKILALRGDIIPDVEPQKDFRYATD
LIAFIKEQAPHFDVIGACYPEGHPDSANQISDIQFLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIYLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A0B1RF17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea rodasii|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFLSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIARDYWENGIRHIVALRGD
LPPGSGKPEMYGADLVELLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNAMFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPPVLA
>A0A2M7JZT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG_4_8_14_3_um_filter_45_15|TrEMBL
MISKFRQVLNSGKFVVTSEIGPPKGTNIEKMLHHIDLLKDKVDALNVTDHQSSVMRFPSI
GGCLAIKEQGGEPILQMTCRDRNRLALQAELLLAYTRGIRNVLCLTGDAIPVGDHKEAKG
VFDLDSVQLLRAIRQMEAGKDLGGNELDGTIEFCAGAIVTPEARPIEPQLIKFEKKVEAG
AEFFQTQAVYDLDNFAKFMQYARQFSVKILAGIVLLSSASMAKYMTENVPGIFVPKYLID
ELASAPRGEALNKGKEIAGRMVATLKKESICDGVHIMAIRREEVVPDILAIAGL
>A0A2W6HDD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAGLSLRADAFIGAFSLEVSAKAMPALRAETDRIPRGTVISLPYLSSEDDDARLAAART
VRALGLEPMPHLSARRVESRAALERFLERAAGDAGVERCLLIAGDLATPAGPFADSASII
QTGLLEQYGIKVVGIGGHPEGHPAMSSEERWQVLQRKCQGIETRGMAPVIVTQFAFDADL
VLAWLDALRTRGITVPVLVGVPGPASISRLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVKGLTSAHGPVSPHFYPFGGVAPSLDWMAQYRQRISSARSVIPEG
>A0A0K0WM60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospirillum sp. Group II 'CF-1'|TrEMBL
MTFREALNAREFLVTAECSPPKGTRIDGLLDRLTPLKNRIHGINVTDNQTGVMRMCPMAM
GLHLKGIGLDPIIQITLRDRNRLAIQSDLLGMSSLGLSQVLCLTGDPPKLGDHPEAKPVF
DIPTQELIRAITLLNGGTDLSGKDLNGKTDILPGAACSPEGDQETEFRKFEEKFDAGARF
FQTQAVFSPEKMEEFMRFASPFSVPVIAGIILLKSAKMARYLNDHVPGITVPPPLIERLD
KCPPGQALESGIAIAAETIRAIRPLVHGVHIMTVGAEETIPRILDQAFG
>A0A1V5HFL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.BinA174|TrEMBL
MNISELILETKKPVFSFELLPPLRGNSINQVFNTIDRLKEFGPKYINITTHHSENIYKED
KDGVIRKVNVRRRPGSVAIAAAIQNKYGIRAVPHIISQGFSKEETEYALIDLAFLGVTDL
LLLRGDTKKLDVEQRKMDCHTYASGLQEQVNNFNKGIALDGSAISAPETPFTYGMACYPE
KHEESPNMESEIFYTKMKADNGADYLVTQMFFDNQKYFDFVERCRAEGITIPIVPGIKPI
HLRNQLNILPKVFRTEIPEDLARELRKCKTDTDAVEVGVEWCLLQSKELMRHNVLGIHYY
ALGATESIYRVAREVY
>A0A2S7ZL59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. T34266-5|TrEMBL
MTLREKHQNGQFTITVELDPPKSSSAQKVFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNEEIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDHGDHPFAQSV
FEVDCMGLLNIAKTLNSGKDLAGNDLDEPTSFYIGATGNPGASDLEIERQKLAAKIKNGA
HFVQTQPIYDLEQAKRYIDKMSEFNVPIMLGLIPLKSFKMATYLHEKVPGINLTQDILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A317BW00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSAGMSLRADAFLSAFSLEVSAKAMPALRAEAARIPRGTIISIPWLASEDDGARLAAACA
VRELGFEPMPHLSARRIGSHAALERFLERAAGEAGVARCLLIAGDLATPIGPFADSASII
ETGLLERHGIKVAAIGGHPEGHPVMSSDERWQALQHKCQRIEARGMAPLIVTQFAFDADT
VLTWLDALRTRGITVPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVKGLTSAHGQVSPHLFPFGGVAPSLEWIEQYRQRVRGARGVIHED
>A0A286H994|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter rathayi NCPPB 2980 = VKM Ac-1601|TrEMBL
MSEQRSESDPACPRVPFSFEVYPPRTAAGSLALTRTVDRLAAAGPSFVSVTYGAQGSSRS
ASLGILRYLLERTATPALAHITCVGSTHAEASRLVREFLEAGVTRFLALRGDRPTGIPED
AAILGELASAAELVQLIHRVQAEREPYGAMPVPGLRNAQCVDVAARPHAEVAVAAFPNGH
PRSRSRTQDIDVLLAKEAAGASFALTQLFFHADDYLRFVDRARAAGLRMPIIPGVMPVTS
PARLRRMLELSGEDLPADLAIALDVEPDDEARMRIGVEYAARLIRTVVDGGAPAVHLYAF
NRDEAVLAVLAESGLLPPGSAPTLPTATSPSTPSPQERTA
>A0A424Z299|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter hepaticus|TrEMBL
MCSFSFEIFPPRKDENIKNLDAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEK
YKIPSIVHLPCIHSSKEKITQILQQCKDRQLNKILALRGDVCNNLEKSKDFSYASDLISF
IQKYKDFEIYAACYPEKHNESKNFIEDIHYLKNKVDLGTNKLITQLFYDNNFFYTFKQNC
ALANINIPIYAGIMPITNKRQVLKITQLCGSKIPPKFTKILEKYENNALALEDAGIAYAI
DQIIDLITSGVDGIHLYTMNKSRAAIKIYEAIKYLIKVS
>A0A5M4AYI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prolixibacter bellariivorans|TrEMBL
MKVIDIINQSDKTVFSFELLPPLKGQNADKLYRTIEELLEFDPKYINITTHRDEMEYRTL
PNGLLEKRTIRKRPGTVAIAASIQNRYNVPVVPHVVCGGFTKEETENMLLDLNFMGIKNV
LALRGDKLKSESIFKPEPEGHAYANELVKQIVDLRQGKYLDPELKNNTPMDFCIGVAGYP
EKHSEATNPDVDLINLRKKVESGADYIVTQMFFDNQKYYDFVDRCRAAGINVPIIPGIKP
LSLKNQVSVLPGIFSIDIPEEFAKEVRKCKNNEDARQVGTEWAIAQAKDLIAHNVPCFHI
YTYGISDNTRQIANAVF
>A0A1Q3Z8P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. 36-9|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFKPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEPSVGGHKYASDLVKQIHDLGIGEYLHGKIESDVDNSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKFFDFVKQAREIGIDVPIIPGIK
PIATKTHLQMLPQVFKIDLPEALINEVLKCKTNNDVREVGIEWAINQSKELLDFGIPVLH
FYSMGKSDNILKIGREIF
>D5Q0V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridioides difficile NAP08|TrEMBL
MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAANVTDFQSAVMRATSLA
TCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLLALTGDHTSVGDHPQAKGV
FDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTPEYSPIEVQLLKMKKKIKAGA
KFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSPGMAKFMTANVPGIFVPDEQIER
LRVAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIMAIGAEENIPAILDAAGL
>A0A270NMW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAGLSLRADAFISAFSLEVSAKAMPALCAEADRIPRGTVISIPYLASEDDDTRLAAAHT
VRALGFEPMPHLSARRVGSRAALERFLERAAGEAGVARCLLIAGDLATPAGPFADSASII
ETGVLEQSGIKVVAIGGHPEGHPVMSSDQRWQALERKCQAIEARGMAPLVVTQFAFDADT
VLAWLDGLRTRGIAVPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVKGLTSAHGPVSPHFFPFGGVAPSLEWMAQYRRRISISQSG
>A7AYB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9)|TrEMBL
MKIIDRLREDGIHISFEIFPPKTDAGYDKVIRAAEEMAGLKPEFISVTYGAGGGTSKNTA
KIASYIKHDLHVESLAHLTCASSTKDEVRSVIASLKEQGIENILALRGDISEDMVFPSED
RFHYAYQLVEEIRRHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSARQMKRSCELSGTVFPRRFQAILDRFGDSPK
AMEQAGIAYATDQIIDLLANGVKNIHIYSMNRPEVAAAIMHNISEIIQC
>A0A2J0UHJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAARLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFRIEVGAYPETHPQASDALADLRHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VHRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
AKLCQRLVEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A317BYC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKVDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQG
>A0A2T1IE94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPVPGSLRAEAFINTFSLEVSAKAMPALRAEADRIPRGTVISIPWLASEDDDARLAAART
VRALGFEPMPHLSARSIGSRAVLGRFLERAASEAGVEQCLVIAGDLATPAGPFADSISII
EAGLLERCGIKVVAIGGHPEGHPVMSSDERWQALEGKCQAIEARGMAPLVVTQFAFDADT
VLAWLDALRARGITVPVLVGVPGPASIPRLLRYAAMCGVGASASMLARYGISIGRLLGPA
GPEVFVDRLVKGLTSAHGPVSPHFFPFGGVAPSLEWMAQYRRRISSVRSVIPDG
>A0A0H3AH49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)|TrEMBL
MTLGHREYKMGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKTLQ
PKFVSVTYGANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQ
NIVALRGDIPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRK
VDAGANRAITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVP
NWMVKQFEGLEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGV
RPQA
>A0A317R7H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromohalobacter salexigens|TrEMBL
MSTREHPLGISFEFFPPNTDAGREKLKGVRDTLAERRPRFFSVTYGAGGSTQARTFETVK
SVRQCGIDTAPHLSCIGSDKGELRERLESFREAGITNLVALRGDLPSGMGGMGELRYANE
LVEFIRKETGDHFQIAVAAYPEAHPQAPSYEHDLQNFVRKMQAGADLAITQYFFSADAYF
HFLERARAQGVEAPIVPGIMPISNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIQAF
GEEVVSNLCQRLLDGGAPGLHFYTLNQATPALRVLDNLRCDSLMHGV
>A0A2T4Z0X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phreatobacter oligotrophus|TrEMBL
MSSAYKPSRYVSRSRLKVSFEFFPPKTEEMEQTLWESIERLAPLEPSFVSVTYGAGGSTR
ERTHATVSRIVKDTSLKPAAHLTCVAATKAQVDEVIRDYWAAGVRHIVALRGDPVGGVGT
AYESHPGGYEGSPELIAGIRAIGDFEVSVSAYPEKHPESPSLDTDIDMLKRKVDAGATRA
ITQFFFDNDVYLRYLDRVRAAGITIPIVPGIVPVQNFKQTAGFAARTGASVPDWLAKRFE
GLENDPATRKLIAAAVAAEQALDLVDRGVTEFHFYTMNRADLVYAVCHLLGLRPNEAAPA
AVAA
>A0A848VNH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermales bacterium|TrEMBL
MKIVDLLEAASNPLISYEIIPPKRGGSLKDILDIVEGLTEFDPPFIDVTSHAAQAYYEEQ
SDGSWKRHVKRKRPGTLGICASVKGRFGIEMVPHILCEGFTREETEDALIELAYLDIQNV
MALRGDNHGYRKPIRGDRTRNEHAIDLVSQISDMNRGNYLEDMIDAAPTDFCVGVAGYPE
KHFEAPNLTWDILNLKRKVDAGAAYVVTQMFFDNRHYFDFVERCRDVGITVPIVPGLKII
TSKRQVQSLPRTFHMEIPESLAAEIEAADAQQTADIGIEWATKQAADLLSAGVPYLHFYI
MSTSRHVSKVVRDLRKMA
>A0A8J5D1E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chionoecetes opilio|TrEMBL
MPASHPSPAESSIALPLLKEFLKHRDNARSGKIYPEDDSHLLYEPEYLSGYHSLKEKIQG
RIESKDKFFSLEFFPPRTKGGAVNLLARFDRMREGDPLFCDVTWHPAGNPGGDTETSSLT
IAGAALNYCGLETMLHMTCCSMSKTEIFRHLQRAKEVGIRNILALRGDPSNCHEDWVAPE
DGFTYAADLIRHIRKEFGQYFVLCVAGYPSGHPQAKSYDDDLLHLKEKVDAGADFVITQL
FFKAQTFIRFVTDCRAIGIECPILPGIMPIQSYESLRHIVRLSKLDVPQDIIDIVTPLKD
NDEAIRNYGIHQTYTLIKELFEADIAPGVHFYTLNREVATTAILKQLQLWAAAPRRPLPW
RIAANHKRSGEDVRPIFWASRPKAYIFRTQHWDEFPNGRWGSSESPAFGELKDYYLFYLA
SKSSKEQLLAMWGESLESERDVWDVFHAYLTNSCNPKTGKKVTKVPWNDDELSAETALLT
EKLADFNKRGVLTINSQPNVNGASSEDLVVGWGMPGGYVYQKAYLEFFTSKENVDALLNV
LPLFPRINYHIINRSGSADFSNCHKHRSTAVTWGAFPGTEIIQPTIVDPVSFRAWKDEAF
GLWEEQWGKLYPENSKSRSIIQHITNNYYLINLIDNDYPKDSCLWDVLESMFAWRTLRQE
NVVRISDSVLRS
>A0A510HE32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacter xylanophilus|TrEMBL
MKEHAVEELPLPGCFRYEIIPLEGIEEGVWEWVYEGERSPTLTITASPARGMGPTVELVR
RLREGGYAGRALVPHLSARLIRDERHLEEIVARLKEAEVEEVFVVGGDAKEPAGKFRDAL
GLLEALKELGSPFERVGIAGYPEGHPFIEEKALMEALIEKSAHASYVVSQVCFDAGRVVK
WVGRIRGLGVRLPVVVGVAAPIEAMRLARIATRIGVGESARFLRKQRGWLLRLLLPGKKA
GLSYDASGFLEALVREGGGEGVSGIHLYTFNDLKSSVGWVRRQGAARGGF
>A0A640KW24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania tarentolae|TrEMBL
MSKFISDAIASEDSKKWYTSYELYPPRSAKAEEDLMNVLVPNFMLQSPVFLDVTWGAGGR
TSDTTMRLCKDLQHAYPDTPINMHVTCTNTPKGLIKEALDFAKTHGIHNILALRGDPPRG
EEFQANPDGFACARDLVRYIHDTYGDYFCVSVAGYPEGHPSRITENSTISDEDYQKELEY
LKEKVDAGASVIITQLFYDPSLYVKFVKRCREMGITVPILAGLLPITTYAGFVRMVSLCK
TSVPSEVKKRVEEFKESPEDLREYGVDQCVKMIEYIRAAGLDYHHLHFYTLNNNAQTFKI
LKRLNALVE
>A0A1H3GE67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnobacterium bovis DSM 14045|TrEMBL
MFKEKEIYLFDGGFGTYYSQKYEEPSHRCEIVNIKYPQRVVDIHKEYICAGADAIKTNTF
GAFFENYGNDYVNIIKTGYNLAIKAKEECNSQVDIFADLGPVVGDEIENQVEEYIKTIDV
FLKLGAKNFLFETLGDARALSEVTSYIREREKEATIVVSFGVMPDGYSADGFFIKDLLEE
ASNDENIDAIGLNCISSAIHLNSLLLRLINNYRFDIKKKPCSFMPNAGYPVVRGYRTFFE
GNIDFFGKQIEHAIELGVAIVGGCCGTTPKYIKQIKDRINNLKENNKKSNSESIKETINS
EIKDELYRDEIQLDKGKKYTSNNGYNSSDKKNNDKNESFKFKKKLFAVELDSPKDDDLSV
FMENAKKLQNAGVDKITIADCPIARPRMDSSLLACKVKRELGLDVIPHMTCRDRNINATK
ALLLGISAEGIRNVLLITGDPIPSAQRDEVKSVYQFNSRKLARYVSSLNQELLNGKINIF
GALNVNAVNFHVELDRAKQKMQEGMCGFLTQPILTEMGLENLRKAKQELNDAIILGGIIP
VVSERNARFMQSEINGIDVDEKIIERYVGKTKEESRQLAVEISVDIAKKIEDYVEGYYLM
TPFNRTDIIIDIIEEIKAQL
>A0A292Z1D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. N23|TrEMBL
MVSVGDESSVGLALATSAAGCGSRAGSSGRRTGRPGAPVWTDRDDGPVTTPTDLSPEIPG
RLADALRSGRFAVTAEVGPPRGADLAPVRRAAQVLRGWVDAVNVTDNQGANVRVSSLAGS
LALLDEGVEPVMQMTCRDRNRIALQSDLLAASALGVPNLVLMTGDRPERGDHPDAAPVFD
LDSGALMAAARTLRDDGTLLSGRAVEPPPRYLLGAVDSPGPSADRFEQKVDGGAQFVQTQ
FVFDIAAFGGWLGQVRDRGLDTRCGVLAGVGPIRSLRALEFMSSIPGVVIPEALQRRLRG
VPADRVAAEGVAACVETLQELRELPGVAGVHVMVVGDERGVPEILEAAGMTRASWVAPTS
>A0A165ADV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylona heveae (strain CBS 132557 / TC161)|TrEMBL
MEKISEKVAALPDDAYYFSLEFFPPKTATGLSNLQARLERMARALRPLFVTVTWGAGGST
SERSLELAATCQRQLGLTTCLHLTCTNMSRPLIDQALESAKALGIRNILALRGDPPRSNE
YHEDETLPATQDSNVEFKYAVDLVRYIRKQYGDYFAIGVAAYPEGHTDESYPEYLDAAKD
IPYLVEKVEAGADFILTQLFFDITSFQKFESTLRNHPSGAFKTIPIIPGLMPVQSYAILK
RTTKLSHATLPEDVTARLDEVRGDDEAVKRVGVDIISEIVETIKRSPSPGARGFHFYTLN
LEKAVAFILERCHLIPPSTPMTPADDFSVVEDGDSFQLDEQKKKERRRYSSTNSMPRNRV
VVEHSSGTGNRPFEAPESEVGVPRDLVSSRATTLAISEGEGALGREATWDDFPNGRWGDS
RSPAYGEIDGYGPSLHVSTAQATKLWGYPVTRDDISQIFSRHITGELDAIPWSEEALSEE
TQTIRNELLKLHQKGWWTVASQPAVDGVRSDHKDFGWGPRNGFVFQKAFVEIFLPSADWA
KLQKKISALDEVSYFAGNAAGDFVSSDEDAVNAVTWGVFAAKEITTPTIIEKESFKAWLE
EAYTIWEEWQRVYPPRSPSAKLLRETRDDSWLISITHHAYVQPNALWDLLLED
>A0A5K7ZT78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina ovata subsp. sediminis|TrEMBL
MHLKNKFDVGKFAILAEMQPPKGVNVSTMVNSATRVRKAVDAFLVSEMGNAVMRMSALGG
AMILQSRGMETIMQANCRDRNRIALQADLLAAYGCGIINVMGVAGEDPSLGDHHQTKAVH
DIDLMTLYRAIAVLQTGKDLAGNELSGAPDFFVGGSVNARASGDELENVLARLNEKIDAG
VNFFIAPPVYDIGAFAAFMEKVDLKTTRIIPTVMLLKSVGMARYLDRHLNVTVSQDLIKR
MMHAPDKATESLAIAAETIKAIKEAGFAGVLISAMGWEDKLEKLVDLI
>E1J545|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli MS 124-1|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A316G803|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Silicimonas algicola|TrEMBL
MTATVSYEFFPPRSVDASFRLWNAVTALKHTDPAFVSVTYGAGGTTRQLTHEAVEAITAH
TGLKVAAHLTCVDATREESLEIAHRYADAGVSHIVALRGDPPKGSQGFLPHPQGFDSSVD
LVRALADTGRFEITVGAYPDPHPEAGSGDADVEWLKRKVDAGATRAITQFFFEADTFFRF
RDRCVKAGIEAEILPGILPIQSWKGAHAFASRCGAHIPEKLVHGFETAERDGRTELYATA
VCTQLCDHLLQGGASHLHFYTLNDPHMTRDVVHALGLAPETALEKVA
>E2BRU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Harpegnathos saltator|TrEMBL
MHSSDLVTFIREQFGDTFCVCVAGYPQMHPESASKQLDLHYLKAKVDAGADFIITQIILE
PQVFIDFVKDCRKIGIQIPIIPGIFVPTDYESLEIMTRVCKLDVPGKIKDNLARMRNEKK
LMKKFILESIIQIITDVIASGTTYGFHLFTLNR
>A0A7V0SFP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MKIHELYRDRFTLSFEIFPPKTPAGEEKLMEALAVFAAHDPGFISVTYGAGGSTREKTLE
LSLKIRDRFGITPLAHFTCVGAGRKDIADYLGEVKRQGIENILALRGDPPQGEKEFTPAP
DGFAHADELVAYIRSINGFTIGVAGYPEGHMEAPDLDTDIENLKKKVDAGADFIITQLFY
HNEDFYTFIDKITKLGITVPVIPGIMPVTSMAQVERVTGMCGAKVPGELIERLKRCATED
QLCAAGVEYSIKQCEELRSWGVRGFHFYPLNKSAAVARILASLNPVL
>A0A172TKG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus swuensis|TrEMBL
MKPDLRQALSQQILIGDGAMGTYLYHLGFPVGISYEELNLTKPDVIGDVHKRYYDAGARV
IETNTYSANRDKLSKFGLEQEVEAINRAGVDIARKAVGEDAYVVGAVGSIRGGRRNNAQL
TEVEADLREQIGALISAGADGILLETFFDVEEMLLALGIVRELGGAKVPVICQFATEDVG
RTLDGYTMEEAFKACREQGADVVGFNCRTGPNGILRALEGVVGHVSSPFSVYPNAGIPDY
VDDKYTYMATPEYFADSALKFAAAGARLIGGCCGTTPEHIRAMADALRGFAPHSPRTAAR
PAATPAAAAQPAAAAPDSGAPAEASAAAPNILELVRQRHTVIVELDPPRDLDIARFMQGS
AALQEAGADAVTMADNSLAVTRMSNLALGALVQQQTGLRPLIHIACRDRNLIGTQSHMMG
LHALGIDHVLAVTGDPASFGDLPGSSNVYDVKSFEIIRMIKQLNEGIAFSGKELKQKASF
VVGAAFNPNVKHLDKAVQRLERKVEAGADYIMTQPVYDIGLIERIYQSTKHLDIPIFIGI
MPLASGRNAEFLHNEVPGIQLSPEIRERMAGLEGEVGRRVGVEIGKELLDAAMQYFNGIY
LITPFLFYGMTAELTRYVWEKTKRHDFDLYPLSK
>D4JP76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] rectale M104/1|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNQYNVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>A0A3C0U880|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium sp|TrEMBL
MHSPLFSLEVFPPKRTSPVGTIYDTLDGLQGVDPDFISVTYGTGKSSDRTLTARIAHTVG
EYGIPCVAHLTAQYLDKDDVDEALDMFSQAKVLGVLALRGDRVEGVEPAGVFEHASDLAA
YIRVRHPEMKLYGACYPEKHPQAATLKSDIDNLKKKVDSGVTHLISQLFYDNEDFFRFLD
AAHAAGIEVPI
>A0A127T532|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
RTDFCIGVAGYPEKHFEAPNIDTDIYYLKRKIELGAHYITTQMFFNNKHYYNFVNKCREN
DINVPILTGLKPLSNKRQLTMVPSIFNVEIPVELYDAMNKAKTNEACEKIGEEWLLEQCR
DLLKNNVEVLHFYTLGKPHVIYNVLKQLF
>A0A1Q6LD75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:217_53_7|TrEMBL
MKIKAILEQKPTVSFEVFPPKQWDKIEGTKAVVKEMVKSHPAFMSVTYGAAGTTSGFTTE
IAREILDDGVTPLAHLTCLTSTRDKIHQVVAELQENCIENILALRGDIPRDFQFPAEQYF
EHAYQLVNEIRTLGDFCIGGACYPEVHPESKNRVEDLEHLKQKVDCGVDFLTTQMFFDNT
VFYNFREMCAIKGIDVPLIAGIMPITKASQLERTVKLSGCSLPTKFVKIVERFGDRDDAM
QQAGIVYAAEQI
>A0A178GBG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. SFB|TrEMBL
MTKRVPISFEFFPTKTDVGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFTIEVAAYPEMHPQADSFDKDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPIINASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>B0K7V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E)|TrEMBL
MLKNENLCTKLKKRKFVVTAEISTPKGVDITKTIEEARKLKGIVDALNITDCPMANMRMS
PIAVAHLLQDHLNIEAIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDEPSRGDTPQ
AKGVYDVDSVGLLKIISAFNRGYDYNGNKLDSPTEFCAGTTANPNDLRDEALEKLKVKIE
AGAEFIQTQPVYDEEILFKFIEKIKNFNVPLLIGILPLKSYKMAVNLNEKVPGIDIPEKV
LERLKDGGREEGINIAVEFIKRIRSEVAGIHIMPLGSTNVVLEIISRVDDLVCDFAENNV
QMN
>A0A0D9ZEX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryza glumipatula|TrEMBL
MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLK
QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNL
GLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLD
QLIEKSKAFPSLTYIAVNKDRESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWK
DEAFEIWSKGWACLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAFKEI
>A0A6B3D565|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID9913|TrEMBL
MALGTASTRTDRARTVRDMLAGGKTTYSFEFSAPKTPKGQRNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVHETEQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNAVF
PDTLKERILTAKDDPATVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A0F6TY60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter amalonaticus Y19|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGSGKPDMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A1I5M415|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas borbori|TrEMBL
MSQEHRYSFEFFPAKTEAGHEKLLNTARQLAAYQPDFFSCTYGAGGSTRDRTLNTVLQLN
NEVGVSTAPHLSCVGDSKAELRELLNIYKDAGIQRIVALRGDLPSGMGMASGELRYANEL
VSFIRAETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGASSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSDSIRAYG
EQVISEMCERLLQGGAPGLHFYSMNLAEPSLAIWNNLKLPR
>A0A7W5Q072|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK313|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERASIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGFHEKCFILVGV
GPLASARTARWMRSNVPGVHIPDAIIKRIEGAEDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLTGRQPWKREANPGDAAIAERLEHLREGKEENQQEMAEAAA
HHPPHQTH
>A0A6L6LAL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSTNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQTNFEVN
>A0A344LR23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium fluviale|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFTPKAGGNHYAIDLVRQINDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFNFVKKAREIGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAIDKCKNNAEIKQVGIEWAVQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>D8LT26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectocarpus siliculosus|TrEMBL
MKIIDKIQQAMEAKEPFYSFEFFPPKTSAGVENLSARMERMATLEPLFVDVTWGAGGSTS
DLTLAISANAQKYLGVEVLMHLTCTNLKVEEIKGALNKAREAGIQNILALRGDPAKGLGN
WEAAEGGLRHAIDLVRLIREEHGDYFGVAVAGHPEGHVDGRTGAEEGGQDDDRRDEGWEA
LELKRLKEKVDAGADFVITQFFYDTEAFLSYVKRCREVGITCPIIPGIMAIQNYNAFARM
TDFCETRVPSDVREALKPITSDDDAVKDYGVDLGIRMCKALTEAGTPGVVLKRVGCGGN
>A0A6L6LLI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQPNFEGN
>A0A0N0JRV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyrobacter sp. AAP60|TrEMBL
MTPTLDQLHEYRTATDTPLFSGLPGDVAVSFEFFPPKSEKMEAQLWDAVTRLKPLGPSFV
SVTYGAGGSTRERTHATVARIIGEAGLPAAAHLTCVAASKAEIREVAEQYWEAGVRHIVA
LRGDAGEPGAPFTPHPDGYASAAELVAGLKGIADFDISVAAYPETHPDADCPQADIDNLK
RKLDAGASRAISQFFFSAETFFAFRDKCAAAGIDAPILPGILPVTNVAQARKFAGACGAA
IPAWMDGLFEGLDEQPAARQLVAATIAAELCRRLYAGGVRDFHFYTLNRPDLAYAICHLL
GKRPVGETA
>A0A545V2W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cordyceps javanica|TrEMBL
MHVKDLLAETKRSGKPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPQFIDITWGAGGRVA
ELTCEMVLQAQAVYGLETCMHLTCTDMGMEKVNDALHKAYKAGCTNILALRGDPPRAQEK
WTATEDGFQYACDLVRHIRANYGDHFDIGVAGYPEGCDDNDNEDELIEHLKYKVDLGGTF
IVTQMFYDVENFIRWVGKVRAAGITVPILPGIMPIATYASFLRRCKHTGCNIPQKWLDVL
EPVKNDDVAVREIGKKLVVEMCHKLMAAGIHHMHFYTMNLAQATRMVLEELSWTPSAERP
LQQALPWKPSKGFGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRLKWGEPKSLRDIANTFVRYLNQDIDSLPWSEAPLTSEADSIKPSLIE
LNQRGFLTINSQPAVDGVKSSHPVHGWGPANGYVYQKGYVELLVSPEIVDQVIHLVNANP
SLTYYAVTKDGNLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGVDW
AHCFEAKSASRALVENVMDNWFLLNIVNNDFHDNTTIFELFKDLEVDGLDIPVDVEAEAP
VAVEADKPAVAQAEAAA
>A0A1G4B2S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum orchidophilum|TrEMBL
MHIKAMLDESQRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGMEKVNDALRKAYKAGCTNILALRGDPPREHEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGATF
IVTQMFYDGDNFVRWVGKVRERGITIPIIPGIMPIATYSSFLRRAKHMNCKVPEEWMTAL
EPIKNDDVAVREVGKGLVAEMCRKIVAAGIHHLHFYTMNLAQATRMVLEELNWMPTSDRP
VKHALPWKQSLAHGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSVKDIANIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSSHPVHGWGPANGYVYQKAYLELLVHPDVYKEIVARVEKNP
DMTYYATTKTGNLKYNASNDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGIDW
AHCFEAGSPSRTLVERIMNEWYLINIVNNDFHQKTALFDLLEGLEVKEYSDIPSESQTNG
AAKEQQNNGNVPAAVAAN
>A0A267DHI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
MESQQNGHAYESDAPKILCRVSSGDSSSSASNATEMNDCHDSRPHSPVLPIAQYRPLISR
INRRIEKGKRWFSCEFFPPRTASGAVNLLSKFDRFAKGRPLFCDVTWHPAGNPMSDAPTS
SIMVASAMLNYSGIDTMLHVTCVGLPEERMTAALERAKGLGLKNILALRGDLPEAPEDGA
GGSGDVSNGDLLGDFKYAVDLVRFIRKRYGSFFNICVAGYPTGHPEASSYADDLLRLKEK
VDAGADFIITQLFFEADTFLKFQSDCRQLGIRCPIIPGVLPIQAYQSLRHIVKLSKLAVP
DEIIRTIEPIKENDEAIRNYGIFQCTQLCRKLLESGEVHGIHFYTLNREVATIEILRNIG
LWHEDLPRPLPWKHSANHERCGELVRPVFWSNRPTSYVHRTLHWEEFPNGRWGGQMRLLL
ASSRTITCSILPFALPRRTG
>A0A0P9WJI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. nerii|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>A0A5N7NN67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella intermedia|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDVKPAAHLTCVDATREEVDRVVREFAAFGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKAEAAL
EMA
>A0A7Z9R0Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MSEKSFLKELDDRILVCDGAFGTQLRKRIPSHVTCLDACNIDSDYLYIVQNIHREYKAAG
ADIIQTNTFGANAKKLEFHGLDEQVEEINSAGAWLAREVAAEDVFVAGSVGPIESSPFSH
EFSAEEVSRAFKGQMEALVESGVDLIMLETFTDSREVEIATQLALTYDLPVVVQIRGMSR
GKLSDGTDICVFARQMENLGVAAAGINDRSPHEVTEILKRLAKVVSLPIIVQPDAGAPRI
SQGKLLAEEYTVAAHLYGEYVSSFVKLGANIIGGCCGTTPEHIQQVKLITEGIPPAEREK
QVFVFEDVPKPFKAEFHDNPIQQIFDEKDAIISVEMRAKTFTQFSAMIRESKNLAKARID
LFDVPDNAGATVNIGAIGTAFRLQQETSIPTIIHWTTRQRNLISTQSHLLEAWALGIEGI
LALSGDHPKVGRFETARIVTDLKGSVQLIELITRLNNNQLINGTSIGEPCNFHIGAGFNI
AENLENQVKHLTQKVENGAQFVYTQPVYTLDDIERAHEATKHLGVKILYGILPITTPRSI
PFLRDNLGIYIPRSIVEQFSETSDAMSTRFGLEMINNFACNLRQQNRVPIDGIYIIPPSN
INWKNKRKAVIDIIEAYRGQIAAE
>A0A698RPV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALADIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLIKEELHA
>A0A2M9GU68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter ruhlandii|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLREILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVAKVNAGANAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAELGDDKASIRAF
GVDVVTELCQNLLDNGAPGLHFYTLNHAEAPLAVWKELSV
>A0A736I7N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. houtenae serovar 44:z36[z38]:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>Q5V5Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)|TrEMBL
MALGTRTVSDSQGVRTLLTSARFELMPFESFDEEISHLPDNATIAITTSPQLGIEKTVEK
TAEAAEMGYDVVPHIAARYVEDREQLESIAERLEQASITDIFVPGGDREEPAGEYESALD
MLEALEETEYSFEEVGITGYPEGHDFIDDETLAESMAQKAPYATYIVTQLCYDPDAVLEW
VEDIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVEDDEYNIRGVHIYTFNQTPDTEKWRHKRLDS
>A0A2C4ZCW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus toyonensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTNRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQVALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKAQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A510UET7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliivibrio fischeri|TrEMBL
MAYSHASHLESLNQNIAELDGNINVSFEFFPPSSEKMEETLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLIAAPHLTCIDASRSELIDIANDYWANGIKDIVALRGD
IPPSGGAPEMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQASRFAKMNNVKIPGWMAQQFE
GLDDDPVTRQMVGASHAIDMTRILSREGVKDFHFYTLNRAEHTYALCHTLGVRPK
>A0A8F9L2Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDRTLSTVLQL
DGEVKVPTAPHLSCVGDSKAELRELLDRYREAGIRRIVALRGDLPSGMGMASGELRYANE
LVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQYFFNADAYF
YFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSRSIQAF
GEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A1N7KKN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium piscicola|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIEPLMEFKPPFIDVTTSREEYVYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEATPGGHASAMDLVNQINNLGRGKYLHDDQACDDHNKFCIGVAGY
PEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVTKAREMGITVPIIPGIK
PIATKKHLKLLPQVFKIDLPEDLINAVENAKNNEAVKQIGVEWAISQCKELLDFGVPVLH
FYSMGKSDNIKKVAGELF
>A0A8D0TU81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MQRSSAMVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMES
GDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIAST
AVNYCGLETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYA
ADLVKHIRSEFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADT
FFRFLKACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIR
NYGIEQAVSLCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHP
KRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKE
ELLKMWGQELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVN
RRGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELR
VNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQW
GKLYEEESPSRMLIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEA
SDPAP
>A0A2V6HVD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MDLLAELEERLVCGDGAMGTLLLDRGVPVDRCLEELCVSDPDRIRSIHEEYVAAGARVIE
TNTFGANAIRLARFGLDNRVREINKAAVSLAKKAALGKEVCVAGSVGPLGISTHEAEERG
IDRAQCFREQFAALLEADVDLIFFETFLNFEEMEIALRAIPESDCAIVSLFACEPEGRLQ
SGMPLADAFARCHDMGAKIVGANCLNGPRAMVQLFEKLPAGDLLAAYPNAGYPRYTEGRY
VYPTAPDYFAKAAREMAAQGARLIGGCCGTTPAHIAAVAKALVDLRPIKSKQVRAMAQPS
RTPVHIEHKAEESLLDKIASGKRVVICELDPPKTLALEKYFGGAQALVDAGCDAITLADN
SLAILRVSNLAVGAMLKERFDITPLLHLSCRDRNVLGLQSELLGMAALGMRHVLPLTGDP
ARVGDHPGAASVYDVNSVELISIIKQLNSGFTHAGKPLKAATNFVIGCTFNPNAKNLDAQ
VQRLERKVAAGAQFVMTQPVFDVDLVGEMHRRVQHLRIPIFTGVWPLQSAKQAEFLHHEV
PGIIVPDSVRAELASYDGEGAQAYGIRLAEKIITAALDFFPGVYLITPFLRYESTTRLAK
FARSL
>A0A6A8U1T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHGATHSLFKHHSQVSAL
>A0A3M3AB73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>A0A2X3QU12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus simulans|TrEMBL
MSRFLQTLSKNVLVADGAIGTILYSEGIDTCPEAYNLTHPKKIEQIHRSYIEAGADVIQT
NTYGANFEKLQAFGLEHQVRDITRAGVRIAKQAANEDTFILGTVGGFKGVKQNDLSLSTI
LYHTDIQIETLIDEGVDALLFETYYDLNELLQVIRATKKKYNIPVIAQLTASSTNYLQDG
TEINEALKQVEAEGADVIGLNCHHGPHHMQQSFTHIEIPQHAILSCYPNASLLDFEDSTI
HYSDNASYFGKIAETLVKEGVHLIGGCCGTTPEHIRFIKQAVEGLKPTLEKKVIPIRRKS
NYPSIPVKKNNLTTKVKAGPTVIVELDTPKHLDTTKFFANVTKLDKAKVDAITLADNSLA
TVRVSNIAAASIIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKV
GHLPGATNVYDVNSRGLTELAVRFNQGLNIDGGALKTKTNFNIAGAFNPNVRKMEAAVKR
LDKKVDCGMSYFITQPVYTVERIQEIAEKTAHLDTPFFIGIMPITSYRNATFLHNEVPGI
SLPDEILDQFEAVKDDKQKTKELSLRICRKLIDEVIKHFNGLYIITPFEQVDFSLELTHY
FKKQTAKNQEAII
>A0A3L8CID3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas prosekii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGNHFHVEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A821WTU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood1|TrEMBL
MTLTHTEKSTASNHCDVHQNGIDNRKMSNSSDYFGEFKHSQSEHTLLKTRANSLLPVKYI
SLTEKIQKRIANNDRWYSLEFFPPRTTNGAVNLIGCLERMAVSEPLFCDITWHTAGDPAG
TKETSTMMIANTMLNYCNIDTMLHITCYGAKKATMIEYLSKAKDFGIRNLLALRGDPPVG
EKWNPEKTDFRYASDLVKFIRENFGDYFVICVAGYPKGHPDSKTYEEDLHYLKEKINCGA
DFIITQLFFQAETFLKFQSDCQAVGITCPIIPGIFPIQAYASFKNIVRLTKLDVPDEITA
HMESIKDNDEAIRDFGVQTCVDLCKGLLDSGKVHGLHFYTLNREYATSEILKQLGFGFED
PPLRALPWKKTSKNHVRSKEDVRPIFWSTRPKSYIHRTSDWNEFPNGRWGISSAPSFGLL
TDYHLFYMKIDATRDELLDEWGHELTCEQDVWKMFVCYIGGKKNSSDKILRHFPWKDEEI
SPETNLIHNELVEYNRKGILTINSQPVVNGKPSTDPIFGWGERNGYVYQKAYLEFFTSAN
NIPALRAVLKNFPGVNYHFVNKSGEVNETNADDEQPIALTWGVFPGREIIQPTVVDPVSF
MIWKDEAFGLWMERWGKLYEPDSRSYSIIEQISNTYFLVNLVDNDYPQGSCLWAVLDAMF
EYQQKTNQDINR
>A0A1S8SK35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium beijerinckii|TrEMBL
MIKELLKDNILICDGAMGTYYSEITGNDVSYCEFGNLNDKETIKRIHKEYIGAGAKLIRT
NTFSANTYDLGVSLETLMDIIKSGINLAKEVTRNTSVLIGASIGPIKTDNLDEFSNEVLE
EYKYIVDCFLENGIDIFIFETFSNYNYLKKISEYIKYKNTDSFILTQFAVKPDGFTRDGL
SAAKLIKEVRNTKYIDAFGFNCGSGPAHILEIVKKIDIENEIVSVLPNAGYPEIIHERTV
YPNNPLYFAKKVNEIRSYGVSIIGGCCGTNPSYIKQLTQIVNENSNVVNANTKSEPKVKS
FEKKAKNTFKDKLENGEFVVAIELSAPIDTDISRIIDGAKICKENNIDLVTVPDSPMSKV
RADSTIISSKIKREIGIEAMPHICCRDKNTNAIRSSLIGSHIENIRNILAITGDPISDAS
KVETKSVFNLNSFRLIELIESMNEEIFKEDSIYVGGALNLNVLNKEVEYNRMMKKIEKGA
KFFLTQPIYDDNAIEFLKMIKERTNVKILAGLLPVVSYRNAMFLNNELPGVTIPDKYVQM
FSENMSKEEAQEIGVKITVEIGKKLKNIADGLYFITPFNRVNMLIEIIKQINA
>A0A520KEX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Verstraetearchaeota archaeon|TrEMBL
MKIFSNFMKELYNGNFVFTSEIEPKKSIKIDYLINKANFLKKYVIACNVTDNPRANAYLN
SIIASYIIQSHTGLETICHMTVRDRNRIALISDILGASVLGIKNILVITGDHTTMGDNPN
AMPVYDIDSTQFIKMLRKMIDEGKDINENPIDGKIEMHIGAVGNPNANPIEVELYKVERK
IKAGAEFIQTQIVFDIEKIKNFIDYLKPSPPFILIGIFPCKSYRIAENIEKKLPGVKIPE
EYKDKLKKAEGNSEKIDEINIEYFSNLIKEIKRNTKASGIHIMTIEYERIIGKIIDSL
>A0A2E4B1E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MHKPSSITSALSQESPLFSVEFFPPKDDAGGRRMLETAEAIRPYSPNFVSITYGAGGGTR
ETTMRYARILQDEYNFEVMPHLTCVGHTVNELLEILEDFAKAGFRNVMALRGDPPQGEDV
FKATEGGLSYGSDLVELIRENFPDFGIGVGGYPEKHPEAKDNIIDLANLKTKVDAGADFI
TTQLFFDNQAYFDFVKSCKDSGIDIPVLPGLLPVLSLGQVRRFCKMCEASLPTSLEKKLT
QADDENHPTIGAEWAAGQINELLQGGAPGYHIYALNKPQSTLQILQSLGIEKTAA
>A0A8D6USW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. corylina|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A8G0GXV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Riemerella anatipestifer|TrEMBL
MKVTEHIKKSEGKTLFSFEILPPLKGQNIQCIFDAIDPLIEFNPSFIDVTYHREEYEYVE
VRDGLLEKRVVRKRPGTVGICAAIQNKYKVDAIPHILCGGFNREDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKNGHTYASDLVKQIQNMNKGIYLDTSLEKAAPTNFSVGVAGY
PEKHMEAASFSQDIGHLKKKVEAGADYIVTQMFFDNQKYFDFVDRCRSEGIEVPIIPGLK
PIATKSQLSLIPHRFKVDLPDDLVVAVTKAASNSEVKEIGVEWCIEQSKDLMKNGVPILH
YYSMGKSESVRKIAEAIF
>A0A1M7N7K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium carnipullorum|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTPGGHASAMDLVHQINDLGRGKYLHNDEKACDELNKFCVGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVTKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEELINEVEKAKNNEAVKQIGIEWAITQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A444VK09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda olearia|TrEMBL
MKVTDHIKKAKGKTLFSFEIIPPVKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTLGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLEIENV
MALRGDAMKEEKYFAPTRGGHQYASELVKQIHDINGGNYLHEVIETDDCASFCIGVAGYP
EKHMEAPSLQSDLRRLKEKVDLGADYVVTQMFFDNQKFFAFVEAAREMGINVPIIPGIKP
IAVKRHLQLLPQVFRVDIPQDLVDAVDACKTNKDVRQVGVEWCIQQSKELKEAGVPVLHY
YSMGKSDNIKAVAKEVF
>A0A1G6KAE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium congolense|TrEMBL
MKIKNIFEEKEVVFSLEVFPPRPDVPIENIYQTLEELKDIDPDYISVTYGAGGGLRKNRT
CELSSIIKEKYDVEALAHLTCINSDQETLNKILARLESKNIENILALRGDKPVDGEALGD
YNYAYQLVEHINKHNDFGVAAACYPEGHLETESLDQDLEYLKQKVDHGVDYLISQMFFDN
SLFYKFRNKAEKKGINVPIEAGIMPVINKKQVGRIIELSDAYFPKKFQKILDKYEDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKAD
>A0A0P0L0B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A3E4W922|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIKAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A497Q5D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MLKRSCQWTWSELQIKAIKKGPRTHSNHNPRETSELPETHLSRLLDNGDFVITAEIGLPR
GSDRTIIDEKVKAVSDYCDSINVPDNPLGNPSMASPIASYFVLEAGAEPIMQICMRDRNR
IAVQSSLYGAHALGVRNVLLVTGDSSEHGCYPDAKSVFDIDSVQALDLATLLAEGFNIEG
EEIEGVPEFYIGATFNPYATPIDEHVLRTEEKVRAGARFFQTQCIFDVTPLERFLRRADH
LDLRVLAGVVPLQSPEMALFMNDNVPEVTVPEKYIKRLEDAADGLEPEEVLKATRPVGLE
IALEIIEDLRRLDIQGLHIMGVGWEESVVEIVKRLGMHPRPKR
>A0A6N8VXI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSVTLRDLITDGRAHVVDGAMGTMLYGKGVFVNVCYDELNLSTPEIVREVHEEYVHAGAE
ILETNTFGANPVKLSGFGLEERTEAINRAGARLARDAAAGRATVVGAMGPLGIRIEPWGA
TAVEEAMAFFKRQARGLIDGGVDGFCLETFSDLSELEAAFRAVRSLTDLPVLAQVTIGDN
GATPGGTTMEAAGAAMAEWGVEVAGINCSVGPAIMLDAVERLAASSGLPASAQPNAGLPR
VVENRQIYMASPEYMGQYARRLVAAGARFVGGCCGTTAAHVRKIRDHVASVQPVRVRAAA
RGGAAERTGRSAIPLAERSAWGRKLATGRFVTTVQIAAPRGWRMEEITRQARALAADGAD
AVFVVGGTRGQAHMDALTTAMLLGDRAGIEPLVRYVCRDRDMHGMISDLLGASAAGIRNL
QIVSGESTDLGPYADSTAISDIDSIGLVNVVHRLNRGLDAGGNDIGAPTELVAGVGLDQA
AVDQAQELSRFAWKVDAGADFAVTRPLFDPERLADFLARADTDIPVIATLLPLSSLRNAE
FMANEVPGVEVPEGIVQRMRAAERRSPAHARAEGLAIAREMFAGVRHLVRGVRVRLPDDD
LGRAAELLGSLEVRRE
>A0A241Q3P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. polymorphum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEIGD
FNYAKDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>R8YW28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lactucae|TrEMBL
MTRRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAEDLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHD
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A842VJZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MTDRPAYSQLCKAIEEGHFVFTGELEPKKILDLEEIYESAEEMKKTGKIVAANVTDGPQG
DAYMSSLAPSYLIQDKVGIEAVWQVTVRDRNRVALFGDVLAGATLGLKNILTLTGDHTAL
GDHKKARAVYDIDSTQFAEMLTLMIDEGIDYEGNELEGGKVEMNFGCVANPNSNPREPEI
FKVGRKVEQGIDFIQTQTAFDIDEAKSFLKDLEQFNVPVLLGVFPLKSYGIAWYFDKFIP
GVSVPKDLLKALKSAEKENKGNKPAKYAALDKINIEFFEPFINEIKKTTKAAGIHCMAVE
YERLFDPLLKNFPKYVNY
>A0A4Y6C8F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcus xanthus|TrEMBL
MKIRNRLNPSDPCFSFEFFPPRTDEGEANLLKALEDLATLQPGFVSVTEGAGGSTRAKTV
ELVLRIKQEAGIEAMAHLTCGGHSPAELRTVLERLSAAKVDNVLVLRGDPPKGQTVFEPA
PGGFRYASEMVRFIREEDFNFCLGGACYPEGHVETPSRDDDLRHLKAKVDAGLDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQIQRFTRLCGATVPMRLALQLERVKD
NPEAMAQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRARS
>A0A842ZMC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MSYRSNLEKILSEGRFVVTAEIGPPKGSDAKKIRDKAEIVRGSANAFNITDNQTAVVRMS
SLAGCVILLQMDLEPIMQMTCRDRNRIGLQSDVLGAAALGVRNILCLTGDHQSFGNHPAA
KGVFDVDSIQLLQIIKNMRDAGVFQSGDPLLAERPSVFLGAAANPYADPFEIQVDLLRKK
IDAGAEFIQTQSVYNVEKFARWMDDVQSQGLDKKVHILAGITPLKSVRMTERMKFHVPGT
DVPDVVYQRMKNASDPAKEGYTIALETIRELKILPGIHGIHITALFWEEIIPALVKDAGL
FHQI
>A0A0M3K1C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anisakis simplex|TrEMBL
MNGTTNGSMLNSSSECEIGASNGSLSLKSSHMSQQCMQKLSQGGPYVPLHERIQKRIADR
SPFFSLEFFPPKTLNGVGNFLTRLDRLREGSPMFIDVTWHLGSDPGNLKKETSSMSIAAS
CLNYCRVDTMLHVTCAQYTREQTLKHLEKSKEMGLRNILALRGDLPNQNENNTVYQFRAL
DMIRWIKEEYDDYFTIACSGYPTGHPEAPSYAADIRYLKSKVDAGAQFVITQLFFDAAVF
EKFVRDCREIGITVPIIPGIMPIQLTIPESILTHLEPIKNDDDAVRSFGIQHAVEMCRHI
LNSGAATSVHLYTMNREASCREILKALGLWTQTPLRSLPWKSFDGNHPLRAKEDVRPIFW
STRPKAYVFRTRDWDQFPNGRWGNSSSPAFNDLADYYLFYLKGQPTRDDQLRMYGAQLES
FEAICKVFVNFITQKPNEQNVKVTRLPWNEQDIDAETSLIKDQLVWCNENGILTVNSQPA
VNGAPSTDPQVGWGKPGGYCYQKGYLEFFTSQKNVEILRRILPNYPRLSCTIINHNGSID
WSNADATTPIAITWGVFPGCEIAQPTVVDPLSFRYWKDEAYEAWMNWATIYPDDSSSRKL
LTRIHDEFCLVTLVDNDFPKPVIIFDVLAEVLRLAGETNKD
>A0A6I3HFL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSVMREKLENSNETVFTAEFPSIDGAGMAKVEKSAARLAPWFDAVNATDNPAAHAHASNT
ASAIAMKMHGIEPIMQIVCRDKNRLAIQADMMGAALHGIENISLLTGDDVTAGDEPETRR
VFDIDSTQAINIARILTTGQYLSGRKINPAPDFYISAVENAAAPPFDYRIERALKKYRAG
AKYLQLQICYHPDRLEKFCAGVAKIAPDLKLIPTIVLVKSAKPMGFMNDKVPGIDIPLDS
INRVASAADQADEAYKLTLELAKHALSLPAVRGLHVTDFRHDDSLDSFMYDLGQKPRN
>A0A2S9TQ81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter cryaerophilus|TrEMBL
MFETLISKLQEDKYLTLETTPQHEPSMHNIVEKIKKFKIDSKVDGFTCTDNPLAKLKYNS
LFAALKLQTEFKKPVIATMTMRDRNKIALQSDLLGANDFDIRAILALTGDPANMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFAVVNAYAKNFGSLEKKMHLKI
QNGAVGVITQPVFDIENVKKLLENFENAKENVEGDKRKAQLIFGVFPITKLRTALFLSAQ
VPGIHVPQFWIDELEKAHNISEEEEYKVGMQLSKNLFDEINRIHPKIHLMTANNKFEVAS
EILA
>A0A0S2DCX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter enzymogenes|TrEMBL
MLPISFEFYPPKTDDQRSQLDKTAAKLRGFSPSYVSCTFGAGGSTLSYTPETIRRLRGKH
GLDAAPHLSCVGGTRGEIRQLLELYRELGCRRLVTLRGDLPSGMASAGDLRYANELVEFI
RAETGDHFHIEVAAYPETHPQARDALSDLENFKRKVRAGADGAITQYFYNPDAYFRFVDD
VRAAGIDVPIVPGIMPIANFSQLRRFSDLCGAEIPRWIAQRMQAYGDDADSIREFAADVV
ARLCSRLIEGGAPGLHFYTLNLAKPTLSVLSRIA
>A0A316A4X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalicatena contorta|TrEMBL
MKIIDRLREDKIHISFEVFPPKTDAGFDRVLKATDKIAELKPDFISVTYGAGGGTSKNTA
EIARHIKEDLGVESLAHLTCASSTKDEVRNVIKNLKELGIENILALRGDIPEGMTFPSED
RFQHASELVEEIHKNGDFCIGAACYPEGHVESENKKEDIGFLKEKVDKGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPILPGIMPITSAAQMKRSQELSGTIFPRRFLAILDRFGGCPD
AMWQAGIAYATDQIIDLLANGVKNIHIYSMNKPEIAEAIMSNLSEIIKS
>A0A351T6E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTVSFEFFPPKTPEMEETLWRSITRLAPFQPEFVSVTYGAGGSTRQRTHDTVKRILDETA
LTPAAHLTCVGADRAEVDQVIEDYWHAGVRHIVALRGDPPEGQDSYTPYPGGYAYASDLV
AGIRAIGDFEISVAAYPEGHVDAPDAQTEIDNLKRKIDAGATRAITQFFFDTDCFLRYLD
RIRAAGITIPVVPGIMPVTNFAGASRMAKMNGASVPDWFANLFNGLEQEAETRKLIAAIA
AAEQCVRLRAHGVHDFHFYTLNRADLTYALCHILGLRATTDQEG
>A0A2I5T340|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. (strain ATCC 39006)|TrEMBL
MSFFHANQREALNQSLAELQGHINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKAIKERTGLDSAPHLTCVDATHDELKAIARDYWQSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPATV
>A0A076J5W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEAQINDFNKGVFVDGSPIKITGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVEKVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A1C3SB29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus glycinifermentans|TrEMBL
MGLLEDIKSRTLIADGAMGTLLYSYGIDRCFEELNVSKPDEVRRIHEAYVKAGADIIQTN
TYGANFIKLSRYGLEDETKQINEKAVRLARSAAGSAYVLATLGGIRTFNKSAYSLDDIKR
SFREHLYLLLNEEPDGLLLETYYDLEEAREVLKIARKETNLPIIVNVSMHEEGVLQDGTP
LSEGLTLLAGLGADVVGINCRLGPYHMIKALEEVPLLKDAYLSVYPNSSIPSLVEGRLVY
ETDDEYFRNSAVEFRNQGARIIGGCCGTTPNHIRAMAEAVKGLPPVTEKRVKVREKAAAA
VQHERTEPALDELAKEKRSIIVELDPPKQLNFEKFLRAAKELKSAGIDALTLADNSLATP
RISNVACGALLKKRLDMRPLVHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVRRIE
KKIDCGADYFISQPVYSEEQLIKIHEETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDAIREKMALAGSDKQKQAEEGLAIARSLLDAACDLFNGIYLITPFLRSDLTAELTAYIH
QKEKETTNVYHH
>A0A358HN13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira lucentensis|TrEMBL
MTAQNNTAAKTDLRVSFEFFPPKTEKMEETMWRSIHRLAPLSPSFVSVTYGAGGTTRDRT
HSSVTRIQGETGIPAAAHLTCVGHTKQEIEQIARKYWDEGIRSIVALRGDLPDAGDTYVP
TPGGYDYAADLVAGLKEIADFDISVSAYPEMHPDAPSADFEIDYLKRKLDAGANRAITQF
FFDNETYLRFRDKCQAAGITAPIVPGILPVTNFGSLLRFAKMCGADVPKRFHWRFDGLDD
DPDTRRMVAFHEAISQVEGLMKEGVTDFHFYTLNRAELTYAICHALGIRGTEQAVA
>A0A6B1E7D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSKLKGLGKRLDARFPKALNAAGSVLAPIEKLVKKPVFGCHMCGQCILHSTGMTCPMECP
KNIRNGPCGGVGRNGECEVDHSMTCVWLKAVDRAGKGRWTDELYQGNPSVDWSLQGQSSW
INTFAGRDHHERTAPQWQRVELRTKRTERDDEMRSGSRFERLLRDGHFVVTCEVNPRDSA
DATELIEYVRTLEGFVDAAHVSDNSFATPKMSGTIAAGLIEMQTGVETILHMTCRDRNRL
MLQADVLGACATGVRNILCLGGDYPTLGDHPEAKPVFDLDSTGFIRILKKMRDEGTFDSG
RELKAAPRVYIGGAVGPTAPPLEFRPHRMAKKLVAGADFITTQLMFDMDMFRDFMKRTVD
LGLTEKTHILVGVGALPGPIAARMVDKTPGCIVPEHVIDRLEAAPKGKRRAEGIKIVVEQ
IQELQEIPGVSGVDIMDLMPDSWFPTAEIVEAAGLQDRPEPACAQGR
>A0A636J8D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Tennessee|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8C5UPD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcebus murinus|TrEMBL
MDHREAKVLPAVHHCPSLGMWASEAGSVRFSVPPSISRNPAMVNEARGSGGLNPRSEGSS
SGSENSKDSSRCSTPGLDPERHEKLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQDDITG
HLHKAKQLGLKNILALRGDPTGDHWKQEEGGFNYAVDLVKHIRNEFGDYFDICVAGYPKG
HPEAESFEADLKYLKEKVSAGADFIITQLFFETDTFLHFVKACANMGVTCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQKIKDIIEPIKDNDAAIRNYGIELAVNLCQELLASGLVPGLHF
YTLNREMATTEVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELSSEESVFDVFVRYLS
GEPNQNGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYDEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDALELLNRPTQSEREAEAP
>A0A3F2S1Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora kernoviae|TrEMBL
MGKIIESIRSTYAATADDPTTRPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTDQLKRILKNARAAGIRNILALRGD
PPIGAERWAPVEGGLSNAMDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMVQWISDCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPTEVLTALDAIKNDDAAVRRYGTQLAVETCRRLLKVGVHSLHFYTMNLATT
VTQVLEGLQLLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRIELWGTPQAEEDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAVIRDNLQWLNYNGFLTINSQPRVNGAPSSDPSVGWGGDDGVVFQKAYVEFFVS
PEKLTHLVKVMNRDYPQLSFHALNRQGEEHRNTPLHSVTAVTWGVFPGIEIVQPTVVDSD
SFAAWKDEAFELWQTQWASVYAEDSRSHEVIQHIYDTYFLVNIVDNDYANDESDIFSIFT
RIITEAMDKEQLRERVLDLETRREKMYDTLASFQSLQEELSGDLRAAHTEIASVRNENLQ
LKDKVRQLQSQLALTSL
>A0A4D7YW77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MRSETARRDGDIRLSFEFFPPKNPEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPTL
DAVRRMIGDSHLATAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYKP
HPEGYENAAALVKGLREIADFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQF
FFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYDD
DLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A1L9C2B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus portucalensis FDF-1|TrEMBL
MSLKTNATYYPAMPSAFKEKLLSDEFIVTSEISPPKGVDASSAFEEAGLVRDYVDAFNVT
DNQRAVMRMSPLAMGHLLKEQGLDIIMQFTCRDRNRLALQSDLLGAYAMGMENVCIMSGD
YPTKGDNPGAKPVYDLDSVQLLGAMNRLEEGFDIAGNPLESVPSFTKGAVCNTEPDQPLQ
LMKLEKKARMGIDFFQTQAVYDIGHFETFMESISHIEVPVLAGLIPLKSAHMARFMNEKI
PGIRVDDELIARMESSTDPAEEGLLICAEQIRELKKVCRGIHLMPIGHYRHITDLFEMAG
LHEKN
>A0A0C4USI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria muelleri|TrEMBL
AYGIHLGTEMCKKILAHGIKTVHLYTLNLEKSALAILANLGLIDMTKIKRPLPWRPPANV
>A0A7X0Z9G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGARLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVAEQIISQN
>A0A7D6TSD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A083ZRX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MGWSSFWDNSGADGDVVRSSNILAGWSIEVMPRTAAKIDDFRNILPDGTRVYIAHIDGTP
IADMVSTAKRLHDEGFPVMPHLPARGISGKNELEDWLKRYQGEAGVTQALLLGGGQKQPA
GSFSSSIDMIETGLFDKMGFTHLHLAGHPEGNRDIDSDGSSRGVDQALLWKQDFASRTDA
RLALTTQFAFEAKVVIEWAKRIGNMGVTIPVHVGIAGPTKLQTLIKFAIACGVGPSLKVL
QKRALDLSRLFVPYEPTDFIAELIDHKAANPDSLIEHVHIFPLGGIKPSAEWMKKHASTG
TLANVA
>A0A815BL97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sordida|TrEMBL
MTLTHTEKNTASNHCHIHENGIGAPKICHSLDNFSELKRSESEHTCLTVKGCSLHPVKYI
SLKEKLQNRISNNDRWYSLEFFPPRTTNGAVNLIGCLERMAVGEPLFCDITWHTAGDPAG
TKETSTMMIANTMLNYCNIDTMLHITCYGAKKATMIEYLSKAKDFGIRNLLALRGDPPVG
EKWNPEKTDFRYASDLVKFVREHFGDYFVICVAGYPKGHPDSKSYEEDLGYLKEKVDCGA
DFIITQLFFQAETFLKFVSDCRAVGITCPIIPGIFPIQAYASFKNIVCLTKLDVPDEITA
YMESIKDNDEAIRNFGVQTCVDLCKALLNSDKVHGLHFYTLNREYATTEILKQLGFGFDD
PPLRALPWKKTSKNYVRSKEDVRPIFWSTRPKSYIHRTSNWNEFPNGRWGISSAPSFGVL
TDYHLFYMKIDATRDELLDEWGHELTCEQDVWKMFACYIRGEKNGSDKIVRHFPWKDEEI
SLETHLIHNELIEYNRKGILTINSQPAVNGKPSTDSIFGWGERNGYIYQKAYLEFFTSAN
NIPALRAVLKNFPGVNYHFVNKSGDVNETNTDHEQPIALTWGVFAGREIIQPTVVDTVSF
MIWKDEAFGLWMERWGKLYEPGSSSYSIIEQISNTYFLVNLVDNDYPQGSCLWAVLDAMF
EYQQKTNQDINHS
>A0A6P8IWR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinia tenebrosa|TrEMBL
MANNDNELCTGDKIASKELLDKINECQGNGKFFSVEFFPPKTFNGATNLCAILYRLHESN
TIPMFVDITWKPSEDPLSDTCQEPTALLICSASRQISRFNTMIHIPYYETTKTQVFEHLL
KAKELGVCGIRALRRGPASLKEDDIGNIELKDGFSSTEQLIRFVKHEFGHHFTIAVTGYP
SGFKTKSSYEEDLRKLKIEVDAGADFITTQMFFEVDFYFNFVKDCRNIGINVPIIPGIFP
IQSVSSLRQLKRTLAVNIPDHIFESLTPIKDDNDAVIDFGVQYAVNMCQQLLASCDVPGI
HFYTFNLETALKRITQNLDLGNSLQHNETCSDDNVRPIFWATRPRSYLIRTSNWDEMPNG
RWGDSSAASFGQIKDYHLFLMGTNLSRNDLLNMWGRELHSFHDVCEIFVCYLTGKENRHG
YKVTQLPWAEDEIATETMSIVKDLVDINKEGILTINSQPCVNGAPSDDPRVGWGKPGGYV
FQKAYIEFFAREEVANEIYKQLKDSKRINFHMVKSCGDNLTNANIYSPNAVTWGVFPGSE
VIQPTVVDPIAFQFWKDEAFALWNQQWRNLYPEGSPSRDVIKTIQETFYLINLVDNDYVA
GNSLFDVLNNVLTSLKHETS
>A0A536FCB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGHFRPARPLAATRRRAHSGADGREALARLAWERRSTGCRASLLSVHPLYIPSQGSCRLN
PRVIVHTPVPASDESGKLARDPRSRLQRSLDEGRAVITVELAVPATVAHEVVIERARALL
RPQIVAVNITDGLRGRPALSSIAAAAIITHADLGVEPILQLTARSRPRNGLVADLLGASA
LGVRNLNCMTGDVPENSTDLYDVDVFALIEMARAFPAGLGMELLGQAEPFCVGAAWSPFA
DDPAYELERLVRKRAAGAQFVQTQPVFDARALAAAVDRMPAALGDLPIIMGLAPVRSSDH
ARRLTGIPGIVIPDRLLDLLDGATSEDDAAERYWAYLDGELEWLARNVPLRGCHLMPIGH
SKRSMRQQSTFERLYACAIKITGPSAAAAAAN
>A0A089PHK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pluralibacter gergoviae|TrEMBL
MSFFHASHQEALNQSLAEVQGQINVSFEFFPPRSSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELKAIASDYWNNGIRHIVALRGD
LPPGSGRPEMYAADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLRKKVEAGANRA
ITQFFFDVESYLRFRDRCASTGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAKMFD
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A661Q2Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNVIDIIKNSDKTVFSFELLPPLKGNDASKIYRTVESLVDFDPKYINITTHRDEMVYIEA
ADGTIEKRTVRKRPGTVAIAAAIQHKYDIPVVPHILCGGFSKSETEHVLIDLNFMGVNNI
LALRGDGLKTDHVFRPDPNGYANATELVEQVVNLRQGRYLEADLKNNAPLDFCIGVAGYP
EKHFEAPNFATDLAYLKQKVDNGADYIVTQMFFDNQLYYDFVDKCRAIGIDVPIIPGIKP
INLKNQLTVLPKLFSISLPQDLATALDKCKNNDDAKVIGTEWAIHQSKDLVAHNVPSLHI
YTYGVTDNTRKIIKAVF
>A0A535YSQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVVMRVPRRVGRGVSGISRLAELLRSGQFVVTAELASSDSADPDAVGRNGDQLRGVADAI
NCTDNTGAHVHLSSMAAAHLLAERGIEPIMQLTVRDRNRLALQADLLGAAALGIRNIVVM
SGDDVTAGDHPEARRIYDIDSMQLIEVAAGMRDRGVYLSGRKLEKAPAFFIGAVENPFAP
PLEFRPLRLQKKVRAGADFVQTQLVFDLPIFTRFMSMAADLGLFEQVFIIPSIGIPRSAR
GARFMKEKVPGLHVPDALIERMEKTPPARQAEEGIRIAVELVNDVRQIHGVAGVHLIGIK
WEEGVTRVAEAAGLLPRPTLSPLATVGGRR
>A0A0I9ZUD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella fujikuroi|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A496ZG12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSTEENGFKSGSNLEKILRAGHFAFTGELGPPRGSDAGEVREKAKHLKGMVDAVNITDNQ
TAMVRMSSWAASILIMQEGLEPNFQMVCRDRNRLAMQSDILGASAHGIKNMLCLSGDHQK
FGDHPQAKGVFDIDSIQLIGMVKKMRDESKFLGGADLEVAPKMFIGAAANPFADPFEWRV
HRLAKKINAGVDFIQTQCIYNMDKFREFIKKANDMGLTDKVYILAGVTPMKSVGMAKYMK
SKVPGMDVPDEVIKRLQGAEKGKVAAEGIKAACEQIEEFKEMKGVAGVHLMAIEWEHKVP
EIAEKAKVLPRPQV
>A0A1C6TLP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora aurantiaca|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTPAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWIAHPEGVRYAEGLVRLVRDSGDFSVGVAAFPYKHPRSPDVDSDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAATGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFEQVADDPEAVRRLGVEQASEMCEKLLDEGVPGIHFITLNRSTATREVWQRLR
AAARV
>A0A0M3C3G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A6B3YU42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIKNILALRGDIPKDKDIIGE
YNYAFELIEKIKASNNFGISGACYPEGHIECKSLDQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQEKSINVPIQAGVMPVVNKKQIERIVKISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDIAV
>A0A099N4Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas plecoglossicida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A845S9J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Fonsibacter sp. PEL4|TrEMBL
MNKDLNISFEFFPAKDDAGHESLWQSLKKLEQFSPKFFSVTFGAGGGERDKSDFLVKKIH
NKSKIPVAGHLTCVDMSKDEINTIALNWLNNGINKIVALRGDVRKKNTKYSPHKKGYINA
ADMVKGLKKLGNFEISIAGYPEKHPESENEIKDLENLKNKVDQGADKIITQFFFNDEKFL
RFRDRAVASGIKIPIIPGILPIDNFEKIKNFSEKCGTSIPNWVEQEFTNLDSDNEIQKII
GASIACDLVKKLQSEGVNEFHFYTLNKYELSYAVCKRLSADKLKINKNQQKEIYA
>A0A350ADG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTTPAVSFEFFPPQSLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRELTRDAVTTLHK
NSGLKVAAHLTCVNATRAETLGIAESFANSGVTDIVALRGDPPKGDGKFTAHPEGFTSSV
DLIEALKDTGRFAIRVGAYPEKHPEAANQAADIDWLKRKLDAGADEALTQFFFEADTFFR
FRDACQRVGIDGDRLTPGILPIENWKGVTRFAERCGTAVPVWLIDAFEKAERDGRQDLLA
TAICSELCSDLLEGGVNALHFYTLNRPELTRDVCHALGVVPRARLQNVA
>A0A3R9J660|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A5S4ZXD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfallas thermosapovorans DSM 6562|TrEMBL
MKNLSKLQQILDSGQFAVTAEIGPPKHSSAEGIRHHAEMMRDYVDATNITDNQTAIVRLS
SIAAGVHVLNCGIEPIVQMTCRDRNRIAMQSDLMGAYSLGMRNVLCLSGDHQKFGNHPTS
KNVYDIDSMQLIYYLRRMRDEKLFFSGEEIKEHEPRFFIGAVANPFADPFEFRVDRLEKK
VEAGAQFIQTQCIFDMERFERFMEMVRERGIDERVHILAGVTPMKSWRAAKYIQNNVSGM
IVPDELVERLKNAEDPKREGVDICIEQIKYIKENVRGVHGVHVMAIAWEEVVPEIVERSG
LYPRPKVG
>A0A5H8NU84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Mikawasima|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5K1NMV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RTEHGDAFHIEVGAYPETHPQATDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWIGRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLRG
>A0A174M9C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerotruncus colihominis|TrEMBL
MHFDRPFLFDGAFGTYYFSKTGDEAPCELANLTAPQTVLDIHREYAASGCAALKTNTFAA
NPVSIPDSVRLNEVIAAGWSLAQRAAQENGARVFADIGGICADTAEADYLTVVRHFLELG
AQNFLFETLACYQDVQRAVGLIRQSVPDATVIVSFAVSQDGYSRRGLYCRALFDQAESDP
QVDAVGLNCSCGPSHMRSLLRALGQRVKPVAAMPNAGYPSSLNGRVFFEDNAGYFAQQLS
ALYMDGADILGGCCGTTPQHIRCAAAALAAAAARPKGTGQPKPQAASATGAGAPGGGRLG
LPRKEIAVELDPPFDHDCSFVLAAASELRACGVDLITVTDSPLSRTRADSLMTAAKIRRE
AGIEVMPHISCRDKNHIALRAGLLGAAFEGIGRVLIVTGDPPMQAGTRGSDGVYHLSSYD
LIAWIHSMNSEVFADAPFLIGGALNVNAANFDAELARAKKKLSLGASMLFTQPIFSDKAV
DHFLRARQELKDCRLFAGILPVAGYKNALFLINEVSGIEIPDNVVRSLEGKTPDEAAAIS
VAYSAGIMRRVYDAADGFYIMTPLKKVNIVRGLIEEIRRYEQ
>A0A1C6HZD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKIDEIFAKKDLVFSFEIFPPKTTSSVDTIYKTLEELKDLKPDFISVTYGAGGSLVNNRT
TELSSLVKEKYGVEAVAHLTCINSTKEEIDYILNDLKAHGIENILALRGDIPEGGVLKGD
FKYAYELISHIKKRGDFNIAAACYPEGHVKGKNLKEDLIHLKLKEESGATHFISQLFFDN
NYFYNFLEEKDKLNIKSSIEAGIMPVTNKAQIERLTSLCGVNLPEKFIKIVNKYEYDRVA
LRDAGIAYAVEQIVDLVSSGVDGIHLYTMNNPYVARKITESISSIINSINKQKAI
>A0A6G9A5D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium symbiodeficiens|TrEMBL
MTDLTIPARADGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTPYSSHPDGYQNSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLQAKVDA
GAARAITQVFFDNDLYFRYLDRVRARGIDIPVVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKNGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A4FGJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)|TrEMBL
MTRVVDRLRPGRTVFSVEFFPPKSDEEERLLWKAIREFEALDPAYVSVTYGAGGSSRDRT
VRTTGRIAGETTLLPMAHLTGVNHSIAELRQVIGAYAAEGIRNVLVIRGDPPGDPMGEWI
PHPEGITYADELVRLVRECGDFCVGVAAFPHMHPRSADLESDTRHMVAKLRAGADFSVAQ
MFLEPEHFLRLRDRLAQRGCHQPLLPGIMPITTPKVLGMTTQLSNMTIPSAVSSVLDPLA
GDPAGFRAAGIEITTKLCEKLIAEGVPALHFYSLNRAQATREVVSNLGLSDGVLKAT
>A0A5Y6M9U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella houtenae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A414PUU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides stercoris|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEKNGYHHAVELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTNEILKCKTDAEAQQVGIEWCVQQCKELMKHHIPSIHF
YSIGAVDSIKEVAKQIY
>A0A6J6FXK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MIELSFEFFPPKDQPGEERLWQELTQLRSLSPKFVSVTYGAGGSTRERTIRVTEEIGQRT
GLDTVAHLTCVGSTQSELSEVLDSYKGAGIKEVLALRGDPVGGPLATWESTPGGFDHADQ
LVKLAVEKGLGVGVAAFPDLHPASNGNVELDLETLLRKEEFGATFAISQFFFEISSWERL
MNQLEKAGSNLKLIPGVMPVTNVKQIVKFAQLSGTQIPDKTRTRFEAVAEDEKAVRELGV
EIAAELCTQLLELGCKSLHFYTMNTAEATVKVCQSLDLGK
>A0A7C6FAX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacterales bacterium|TrEMBL
MFEKFCKQLHSKKPFITVEISPPHGASIKPIIEKIESVNLQDKVTGFSVTDNPLAKLKMS
GILSAIQVQQRFQKPVIATMSMRDKNKLSLQSTLLGANDLDLRAILALTGDPAKYSDQPK
VKGVLERDSTLLLSIIYRLNNGFSYSNKELNPKPKPIYPFAVSNAHAKDMKRLKKNMLKK
LNYGARGIITQPVYTVKSAKKLLEIFEEAKAESVRDTAKNAELILGQFPVISARTANFIS
DKVPGIYVPKSIIEEMDLAAMDGKGKEQEVGFNLSKEIFDNFLKLHPKMHLMTHNRFDLC
TQLIGDAL
>A0A5T2L7W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRNSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A496R422|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MLIKEILSEGKTAVSYEFFPPKNPLGWEKLYQTITDLNHLNPAYISVTYGAGGATREHTH
KLVTQLVRETDAEIVAHLTCVGHSRDEMKSILDRYAESGVHNILALKGDTPSDRIVGRSK
PPGAFPHASDLVFFIKDNYPGMGIGVSGFPEGHPSSVNRLEELVFLKEKVDAGADYIVTQ
LFFDNRDYYDFVDRCIIAGITVPVIAGIMPVTGLSNMNHMAKLAPRTRFPSGLIRAVNRA
ETDEGVEMAGTHWATEQMRDLLDRGAPGIHLYTLNNSASTIRMGESLGLVGFHNLR
>A0A6P2SKW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MNTIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVV
>B6VLT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 / 3105-77)|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSIGRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCKIARDYWNNGIRHIVALRGD
LPDNGEKPKMYGVDLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQLQRFAAMTNVRIPSWMTRMFD
GLDDDPESSNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A3V9CFM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enteritidis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2K4BVM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus auricularis|TrEMBL
MSQFLTQLKDNILVADGAIGTLLYSEGIDTCPEAYNLTHPDKIEKIHRAYIEAGADVIQT
NTYGANFEKLKAFGLEHKIKQIHQAAVAIAKRAAKPETFILGTVGGFRNITQTKLELSTI
QYHTEVQVDTLVEAGVDALLFKTYYDLEELTNIVKLTRQKYDIPIIAQLTASNTNYLKDG
QPINEAIQAVIDSGANIVGLNCHHGPHHMVHSFSHIELPKNAYLSCYPNASLLDIENDTI
QYSDNAQYFGQMAQKLINEGVRLIGGCCGTTPEHVHFIKESVKGLKPVSHKNVVPMTQRK
SKGTNNENRNNLTHLVKTRPTIIVELDTPKHLDTTTFFDNVKKLDEEGVDAITLADNALA
TVRIDNLAAASIIKQQYNIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAVTGDPSRM
GNLPGATNVYDVNSKGLTEIALRFNEGINTDGDALKKKTNFNIAAAFDPNVRKLEVAVKR
AEQKIKHGTNYFITQPVYSTDKIKEIYEATKHLDVPFFIGIMPITSYNNALFLHNEVPGI
KLSDEVLERFEALKGDKEKTKAYSLSLSQELIDTVHQYFNGLYLITPFQNVDITLELAQY
SKSITSTKQEAIS
>A0A193K8X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio breoganii|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLVAAPHLTCIDASREELITIADDYWKNGIESIVALRGD
IPPGGGHPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIVPGILPVSNFKQASRFAAMNHVKVPGWMAQQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQQVAV
>A0A1B9MB02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNQKTVFSFEVFPPKKTSPLATIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVQPKDDF
RFASELVTFIKENGDFNVIGACYPEGHLEASTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKAHDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVATLLAVPKSK
>A0A3S4UWK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidipropionibacterium jensenii|TrEMBL
MQPSKTSTATIADLLARPGRPLRSFEFMPPRSEEDVYRLWQATDSLVPLEPDFISVTYGA
NGSNRDRTLRCTRHMVASGLRTVGHLTCVSQSVAELEQAVCDYRDAGVDHILAIRGDMPG
GATEPWLARPDGLANATELVRLVKRVNPQACVGVGAFPDGHPASGDLDLDARILADKARA
GASFAITQLFFIPEHYTRLVARVRALGCDIPIIPGIMPITSYGQIRRFGDLSGTDVPADL
VARLTRVADDRAAVREIGLEAAAQLCCRLLDEGAPGLHYYTLNRSRATTELHSMVRDRRP
QLWDR
>A0A439J6L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRSYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A5I0CA26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella virchow|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A439IC17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAPRHQVDAVIREFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A439IBD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MSARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRRPWKREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A1B9MJ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDINPNVQPKDDF
RYASELVTFIKENGDFNVIGACYPEGHLEAATLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKARDMGVNVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQDVDGIHLYTMNNSYIARRISEAVSTLLAVPKSE
>A0A3A5XZA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AF25-17LB|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPKELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A819R564|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood2|TrEMBL
MTLTHTEKNTASNHHDAHENGIGAENMSNSSHHFVDLKRSESEHACLAARGNSLQPVKYV
SLTEKIEKKIANNDRWYSLEFFPPRTTNGAVNLIGCLERMATGDPLFCDITWHTAGDPAG
TKETSTMMIANTMLNYCNIDTMLHITCYGAKKATMIEYLSKAKNFGIRNLLALGGDPPVG
ETWDPEKNDFRYASDLVKFIREHFGDYFVICVAGYPKGHPDSKNYEEDLGYLKEKVDCGA
DFIITQLFFQAETFLKFQSDCRAVGITCPILPGIFPIQNIVRLTKLDVPDAIQTHMESIK
DNDQAIRDFGVQTCVDLCKALLDSGKVHGLHFYTLNREYATTEILKQLGFGFEDPPLRAL
PWKKTSRNHVRSKEDVRPIFWSTRPKSYIHRTSNWNEFPNGRWGISSAPSFGVLTDYHLF
YLKIDAAHNELLDEWGHELTSEQDVWKMFACYIGGEKNSSDKIVRHFPWKDEDMSLETNL
IHNELVEYNRKGILTINSQPAVNGKPSTDPIFGWGEKNGYIYQKAYLEFFTSANNIPALR
AVLKDFPGVNYHFVNKSGEVNETNTDDEQPIALTWGVFPGKEIIQPTVVDPDEAFNLWME
RWGKLYEAGSRSYSIIEQISNTYFLVNLVDNDYPQGSCLWAVLDAMFEYQQKTNQDTNS
>A0A6Y0YY29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Paratyphi B|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7Y3BSH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MRIADLYAADEGPVFSLEFFTPKNDAGRKALFRAVERLQAVKPGFVSITCGAAGTTRERT
ADLAIELQNAFGLTAMAHLVCTGTTQSELEETLRHMQANGIENILALRGDPPKGATDWAP
VEGGFAHANELAALVRKGFSLGLGGACYPEKHHEAPSLAADIQNLKRKVEAGAEFLITQL
FFDNEKYWSFVAQVRAEGIDVPVVPGIMPVLNLTNLQRIASLSPGTSIPSELEDALRQAG
DDDEAALRAGVSFAAKQCRALLAKGAPGIHFYTLNRSKATLRTYAEL
>A0A1M2ZAU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium 43-6|TrEMBL
MGTYVAEKYNIMFCEFENLHNPERILDIHKEYIAAGAKAIKTNTFSANTFTLKTDFDTVK
SIIDSGCSLAKQAVSGTDTLIFASIGPIRDKDSELTIPEQKKIIDVFFDNHINTFIFETF
SEYETLITLSRYIKEKDKDSYIIAECTVNADRYTSRGISVSEIIKALDKTDEIDACGFNC
TCGPLHLLEIAKELPKISKPVSIMPNAGYPTFIGGRSFYKSSPIYFGEKLSEIHSCGVQI
LGGCCGTGPDYIKQATKALEATENSEKTETVTITVKEKTAKPKTKKKNLIAVELDSPLDT
NAEYFYEGAKILSRAGADFITIADCPLSRARMDSSMLSAKLKRDFNIDAIPHLTCRDRNI
NATKALLLALYAEGIHEILAVTGDAIPSADRNEIKGVYNFNSVMLASFIGNLNETIFSEN
PFTISCALNINQNNFEAELKKAKRKEEAGCSRFLTQPVYTDASLENLALAKQVLKSPVLA
GLMPVVSYKNALFINSEVPGITIPDAIIKAMEHADREKAAQIAVESILAISEKIKGLCDG
YYLITPLKRVDIIETIIKGL
>A0A1N7PEY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kroppenstedtia eburnea|TrEMBL
MTHHPDLRAALTDSLLVGDGAMSTYLYQQGIPVGMTAEELSLSRPDWIEEVHRQYVEAGA
QLIETNTYGADRERLSRYGLEGKVSRINRESVAIARRAAEGKAYVAGAVGSINAGRVPRW
SPAEYRDLYEEQATALLYGGVDGIILETFFDLEELLLALEVIRPLTDRPILAQLTMLEVG
RTRDGHTLTKAFVELQKQGVDGVGLNCRVGPLQMEQALEKTAVPDGLILTAFPNAGRLGR
RDGEYQYESTPEYFGNRAKALREQGVRLIGGCCGTTPDHIRKVAEALQGLPPVPRVNPEL
PEEEVVSLPLQVRSRPTVVEQVRKETTVIVEFDPPRDLEIHDFLQGAEALHHAGADAITL
ADNSMATPRMSNMALASILKSRTKVEPLVHITCRDRNLLGQQSHLMGLHALDIDQILVVT
GDPTRIGDLPGASSIYDVNSFDLIRMVKQLNEGISFSGKPLRQRGRFVVGAAFNPHVSRM
EAAIRRLEKKVEAGADFIMTQPVYDVETLKLVHEATRHIPIPIFIGVMPLTGHRNALFLH
HELPGVKIPATVMERMRDLKGPEGRETGVGLAGELLDEAVSLFNGIYLITPFHYWEMTAE
LTRRIRKRGKIRPIAAVHRS
>A0A816M311|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria magnacalcarata|TrEMBL
MILTHNENRTLSSHFNTYQNDAGAEKISSRRFNNFERSDSETRLLTAKGCCLESIKYMSL
AEKIHQRIANNDRWYSLEFFPPRTASGAANLIGCFERMAVGQPLFCDITWHPAGDPAGTK
ETSSMMIANTMLNYCSIDTMLHITCYGAKKETMLEYLWRAKEFGIRNLLALRGDPPVGEE
WIPEKSDFRYASDLVKFIREHFDDYFVICVAGYPQGHPDMASYEKDLRYLKEKVDCGADF
IITQLFFQPETFIKFESDCRSIGIQCPIIPGIFPIQAYASLKNIVRLAKLDVPEEILACI
EPIKDNDEAIRNFGVQICVDLCRILLDSGKVHGLHFYTLNREYATIEILRKLDLWLEDPP
LRALPWKKISKNYVRSKENVRPIFWSARPKSYVHRTLNWNEFPNGRWGLSSAPSFGVLTD
YHLFYMKIDATRDALLDEWGHELADEQDVWRMFACYIAGEKNGTDKIVHHFPWKDEDISP
ETNFIHDHLIKYNRKGILTINSQPAVNGKSSTDSIFGWGVKNGYVYQKAYLEFFTSEKNI
PALRAVLKKFPGVNYHFVNKSGEVNETNTDGEQPIALTWGVFAGREIIQPTVVDPISFMI
WKDEAFNLWMECWGKLYEQGSRSYSIIEEISNTYLLVNLVDNDYPQDSCLWALLDAMFEY
QKANSKDNNC
>A0A7X7GVL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MKISEALQRSEPAFSFEFFPPKDPEGVEGLFQTISELKAYEPTYVSVTYGAMGSTRGLTV
ELVRRIKQEVGIEAMAHLTCVNSTREEIDAVLQDLRAGGIENVLPLRGDPPRGETTFKRP
EGGFAYASELVAFIRERYDFCLAGACYPETHPEAPSPEADLQHLKEKVDAGADFLITQLF
FDNEDYFAFVERARNAGIHCPIIAGIMPITNVGQVKRFTQLCGTRIPAPLLARLEAAEGD
AQAVRAIGSEHASQQCRGLLERGVPGIHFYTLNRSTATRDILDYLRAEGIAPPTSSRQVT
GARGVAAG
>A0A7Y5FB23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MHIQDILATNSTTFSFEFFPPKTEQGADELFTNIAEFEALQPSFVSVTYGAGGSTRELTH
DLVVRIHGSTSLDPIPHLTCVCHSEGEIREIVARYAQEGVSNILALGGDPPRGMENYDRS
RDAFRHAADLVRFIRAFNDSGAHADKRGFGIGVAGFPEGHPTTPNRLLEMDHLKAKVDAG
ANYIVTQLFFDNRDFYDFRERCELAGINVPIIAGIMPVTSVSGLKRMAELAAGARFPAPL
LRSLRRAGDSADAVKRVGVHWATEQCRDLLDHGVRGIHFYTLNKSDATKHIYLSLGLRSD
G
>A0A7X9IU21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
AAPRAGKSRLARRLAAGELVTTCELLPPKSVDLSALLRKARQCREAGVDAINVPDGPRAS
ARVSSMIAALAIEREVGIETVLHYACRDRNLIGMQSDLLGGFAAGLRNVLIVTGDPPKLG
DYPDATGVFDIDAIGLTQLARNLNHGLDAAGHPIDPPTALHHGVGADPGAPDQARELDRL
RRKLEAGAEFIVTQPVFRPEVLFRFLDAIEAFRGGVPLIAGVWPLVSLRNAEFLQNEVPG
VDIPPAILERMARAGSGEEAKREGVAIARETIAAIRGRVQGIQVSAPLGLVALALAALGD
LLPPQAGGPDGTSGGGR
>A0A6H9JTJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AY2-1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2N9MTR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfopaludibacter sp. SbA6|TrEMBL
MTTPMTTRAQEFRDQLSRRVLVADGAMGTMLYARGVFINRCFDELNVAQPDLVRGIHQEY
VKAGAEILETNTFGASRPRLAAFGIAEKLKDINRAAVRLAREAAKDGPFVAGAVGPLGVR
IEPLGPTSFAEAREAFREQIDALLEAGVDLLIFETFGNLDELREAITAAHEASGGEIAIV
AQVTIDDFGHLPGGTDTETFTRALDSWPVDVIGLNCSVGPKATLETIERMMQYSSKPMSA
MPNAGLPMRIEGRNIYLCSPEYMAQYARRLLWAGVKIIGGCCGTTPDHIKLIRSETRSLQ
PAQKKLAITVEEPQAKAQALAPVPMAEKSKLGAKLAVGKFVSFVEILPPRGIDASREIDG
ARRCAEHGIDCINVPDGPRASARMSAQVTCQLIQQQAGIEAVNHFCCRDRNILGIQSELL
GTHTVGVRNLICITGDPPRMGAYPDATAVFDVDAIGLVNIVRNLNHGLDIGGNPMGSQTA
LLIGVGANPGALNMDEEIRRFEWKVEAGAEYVVTQPVFDLDDLERFLKRTEHVKIPVICG
IWPLTSYRNAEFMVNELRVPVPEEFMERMRRVDNAEKAREEGVAIAREMVTRVRHLVQGV
QLSAPFGRYQMALDVAEAIGPR
>A6W769|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)|TrEMBL
MGPAVSDGLVADLRDAQRRFSVEFSPAHDEEGAQRQWRAVERLARLRPVFASVTYGAGGG
TREGTVELASRLAARTDLRPVAHLTAVGQSVPQLRGVVRDLLAGGVTDVLALRGDPDGDP
RAPWRAHPQGLQHADELVRLALAEGVRSAGVAAFPLGHPESRDLDEDLRHLLGKFAAGAG
FAIAQLTFDVEDFLRLRDRLAAAGCTAPLVPGLLPVTSPKVLEVTRRLTDGHEPSWLQRR
LAPFLDDRGAFREEGVRLALEDGRRLLAEGVPLLHLYSLNAAGNVETLVEELGLAGPR
>A0A2E7BRX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MRVIEHLERADEPLISFEIIPPRRGGDLTSLLGLIDDLVAHRPPFIDITSHPAVVSYEEG
PDGIRKVIKRKRPGTLGVCALIQHKYNVDAVPHVLCRGFTREETEDFLIELHYLGIDNVL
IIRGDDNGYDKPVKEGRSANCFAIDLVSQVGDMNQGQFLEPYLQALPTNFCVGVAGYPEK
HMEAANLDMDIRRLREKVEAGADYIVTQMFFENSHYFKFVEKCRDHGITVPIIPGIKVLT
VKKHLTNLPRIFNCEIPTALADEVEAAEKGQVLDIGVEWTANQAQELLDAGVPSVHFYVM
QSSKPINKVLKRLKR
>A0A1H2C9J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter mallensis|TrEMBL
MKITDHITNANGKTLFSFELLPPVKGRSIQEIYDAIDPLMEFNPPFIDVTYHREDYIYKK
HESGLLEKVSYRKRPGTVAICAAIINRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADPSFVPTPGGHAYACELLEQVTNMNKGKYLYEDHDVVNADFCIGVAGYP
EKHFESPNLKTDFRYLKQKVDNGANFIVTQMFYDNNKYKEFVKLCRENGINVPIIPGLKP
ITSSKQLINLPKIFHIDIPEDLADAVQACKSEKDVKDVGIEWMINQCKELIEFGAPVLHF
YTMSNPGPTKRIAEAIF
>A0A1Y4DG57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. An279|TrEMBL
MKVINLIKSSEKTAFSFEILPPLKGTGIEKVYETIDLLREFDPKYINITTHRSEYVYTEL
GNGLFERKRVRRRPGTVAVAAAIQNKYGIPVVPHVLCSGFTREDIEYMLLDLQFLGITDL
LVLRGDKAKHQSVFTPEPGGYSHAIELENQINDFNRGIFIDGSPIKEPVHPFGYGVACYP
EKHEEAPNMEQDIYWLKQKIESGAQYAVTQLFYDNAKYFAFVDRLRAEGINVPIIPGIKP
FGKLSQLSVIPKTFKVDLPQTLVAEAMKCHTDAEAAELGVEWCINQCRELMRHGVPSIHF
YTVGAAQSVSRVAKAIY
>A0A1Q3Q6I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium 37-13|TrEMBL
MKVTEHLANTKNTLFSIEVLPPRKGKTINDLLSVIEPLMEFKPPFVDVTYHREEIIYKKR
IDGLIEEVPVRKRPGTAGICVAIKERFKVETVPHLICYGFTPEETEDALFTLHYLGVHNV
LLLQGDAGHNKSQNEKRIHKYASELVEQVANMNKGRFLHEETENELKTDFCIGVAGYPEK
HIEAPNLKSDLKWLKHKVDMGADYIVTQMFFDNQKFFEFEKKCRAAGINVPIIPGIKPLT
AKGQIRTLPKVFNIDIPEDLVDEIQKCKDDKQVKQLGIEWAIAQSKELKAHGVSCLHYYT
MSRHEATIEIARAVF
>A0A149SQP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter thailandicus|TrEMBL
MIRSIGQVRANLMTESSIELLPSRILELSGVLPDLDRGSRVFVTWLPGVPFADVLAACDL
LKLCGYLPVPHVAARSIRDTQHLRNICTALIERDIPRMLLIAGGADKPAGTFTDTVQVLE
TEIPAQAGIRTVYVAGHPEGHPQATEKQLEQYLLRKQELARAQGLNMQIVTQFCFDAEPV
LNWEKRLRAAGVRLPINLGIYGLTTPRTLVRYGLACGVGQSLRFMQKQRWKLHRWFTPCN
PKDLVDAIAGSIAETPDTLFHGLHFYPFGAIARTLEWRRNFSCSTYGEPS
>A0A4R3L6S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudofulvimonas gallinarii|TrEMBL
MHPSISLEFYPPKNDEQRAQLDKTVGRLATLQPDYVSVTFGAGGSTLSYTPETVSGLRQR
HSLDAAPHVSCVGGTRAELSELVARYRDMGCRRVVALRGDLPSGMGHSGDFRYASDLVGF
IRAEHGDWFHIEVGCYPEVHPQAEDAHADLRALKIKVEAGANGAITQYFYNADAYFRFVD
EARRMDIDIPIVPGIMPIANFTQLRRFSDLCGAEIPRWLAKRMTALGDDVAAVRELGADV
VAALCRRLLEGGAPGLHFYTLNLAKPTLAVVERL
>A0A4R1N0H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. BL9I2N2|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLATLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKSGANSAITQYFFNADAYFRFVD
DAKKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCGRLIDAKVPGLHFYTLNGAAATKAICERLGV
>A0A2R7J703|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. HMWF008|TrEMBL
MGVAAIHPAWEVAPAFITEGYSLEMTAKDRDALTLAAPHIAPDTPIAITFLPGETMDARI
AAACHVRALGFEPMPHLSARRIASQDELAEMVERLTIEAGAKRMFIVAGDPPVPAGPFAD
TLSVLRTGLMETYGIKAIGIAGHPDGHPAMDTDGLWQALDEKCAEISARGMAPLIVTQFG
FDAAPFLRWLKDLRARGIDAPVRIGVPGPAGIKTLLRFAAHCGVGASAAVMTKYGVSITK
LLGTAGPDALVDALAAGIGAEHGPIRLHFYPFGGLERTVSWINDYSAAHVGAEPGARA
>J9G4J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gut metagenome|TrEMBL
MTVSQFLQTPHATAFSIEVLPPVRGKSIENVYRTIDRLMAYNPAYINITTHRTETIYHEV
EDGRFERLSVINRPGTVAIAAALKGRYGLPTVPHLICSGFTRAEIENELIDLSFLDITDL
LVLRGDRAKGDNRFIPTVGGHEHAIDLCKQVNAFNEGLLIDGTQCCVPSQPFTYGVAGYP
EKHDEAMNWDEDVKQVIEKVRAGAQYVVTQMFFDNKKYFHFVDKLREAGITVPVIPGLKP
LTTLNHRSMLPKTFHIDFPAALVRELHRCQNNDDVKAVGVDWAIQQARELKAAGVPSIHF
YSMNAAASIEKIAQAVW
>A0A6L4AHL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MEAAQRSDAGRKSGKPYYLATEIDPPKGTNLAGFLETAMNLRGRVDAIRVTDSEHAIMRM
SPLAPCLALKEKGLAPVMVLNGRDRNRISFQGDLLAASALGITDIVIREGHDPAEGDQPV
ARTSGDLDLAVMLKCATSLNAGRDLAGEPLDGATSLSIEVSLELSDDASRNREQAESLRR
MKDLGVSSVSLGPTYDINIIEQFLPIAEETGIRLYLSVMLLKSVTMIRYLNNLKGVPSIP
QEYLKKMMDAPVKQDAGLTIGAEFIRTVGPMADGVVLLAIGWKDRLPDMLDLLGR
>A0A846MKP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharococcus thermophilus|TrEMBL
MGLLQDLKERILIADGAMGTLLYSHGVDRCFEELNLSKPEDILHIHEAYIAAGAEVIQTN
TYGANYVKLARYGLEDEVPAINRAAARLAKQAAGNKAYVLGTIGGLRSINKSAVSIEEVK
RTFREQLFVLLNEDVDGLLLETYYDLEELETVLAIARKETDKPIIAHVSLHEVGVLQDGT
PLAEALARLEQLGADVVGLNCRLGPYHMIRSLEEVPLPNRAFLSAYPNASLPDYRDGRLV
YETNTDYFKETALAFREQGVRLIGGCCGTTPKHIEAMAGALTDRTPVQTKTVKRRHISIS
LQSNEPNAVPPLQDIVRKRRSVIVELDPPKKLGIAKFLEGAKALKEANIDALTLADNSLA
TPRISNMALGSIVKEHLGIRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVER
LEKKIQCGAHYFITQPLYSERQIEEVYEATKHLETPIYIGIMPLVSARNADFLHHEVPGI
TLSEEIRLRMAACANDPVQSAREGIAIAKSLIDAAFDLFNGIYLITPFLRYEMTAELVRY
IHEKEKAAQERKVLHG
>A0A8F6AV23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulophaga sp. HaHa_2_95|TrEMBL
MKVTDHIKNANGNTLFSFEIVPPVKGNSIQELYANIEPLMEFNPPFIDVTTSREEYVYVD
KAGLYDKKITRMRPGTVGICASIKHKFDVDTIPHVICGGFTKAETEYMLIDCHYLGIDNV
MALRGDAMKEEKYFKPTEDGNCFASELVTQIQNLNQGRYLHDDVQGEDKSNFCIGVAGYP
EKHLEAPSFKSDLIRLKQKVDAGADYVVTQMFFDNQKYFQFVEAAREIGINVPIIPGIKP
IAVKRHLQLLPQIFSLDLPHDLVEAVEACKNNAAVRQVGVEWAIQQSKELKAAGIPVLHY
YSMGKSNNIKAIAKEVF
>A0A0E4G9U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas zehnderi OL-4|TrEMBL
MTLNKGGQCFCLVLGEEKHINKFKEALQDKKTFAVTWELVPGRGAREKLQENALHAAEQA
AQDGRIHALTITDNPGGKPALAAAWLGAEILKMGIEPLVHFTCKDKNRNQIESELYALDR
ANIRNILVMTGDYPVSGFKGRPKPVFDLDSVQVMDLVANMNKGLDPDNTGNLIHKPSDFF
AGGVVSPFKASEAELLTQYYKLSKKVNQGAGFIVTQLGFDARKFQEVLKITREFSPDIPI
IGNLYILPFGVGRIMNSNQLPGCVVTDQLLAELDQEREAADKGQSARLLRAAKMYAFMKG
MGFDGVHIAGHNIKYEQVKYIIDQGEELSADWMELIAEFDYPQPQGFYYFKKDPQTGLNL
DQPVNRAEWTPEYKVGINHRLMRLVHQLFFTPDKKLFPLMRRYYQGVKNPRKYGLEHFLK
VIGNGCRDCGDCALLDIAYLCPMSQCPKNQRNGPCGGSYNGWCEVFPGEQKCIWVKAYAL
LKAYSEEEQLQTSYVPPVNWDLYQTSAWYNYYTGRDHSAVIPSAEATEKKLNC
>A0A1C4Q6W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. IgraMP-1|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVTAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A1M5MAS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseolinea serpens|TrEMBL
MFLDKIKKRKSGILLYGITPPKAQTPVEKLPSIAEKSLHTLSGLDIDALIVYDVQDESTR
TNEERPFPFSSALDPFTYTSQYLHALTIPKIIYRPASMFSKEELADWLDRLKSNGFYPVF
VGLPSPDFVPKTTLAEAYEIWRHNHEAHSVIGAVTIPERHAILKDEDVRMMDKVNCGVSY
FISQCIFNVQYAKQTLDALVNTCQARKQELPTIIFTLTICGSLKTLDFMEWLGIHVPEDI
KQELKVCSNPAGRSVEIATEIAKDLIHYCQERSIPFGFNIESVAVRKEEVDASLELLETV
NRLLKVNGLRNESTLRVKSDLS
>A0A525D761|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MEADKSSIPPQQTRLIAEIDPPKGTRLDSFLDNALRVRGRVDSVRVTDGEHAIMRMSPLA
PCLALLEKGVTPTMIINGRDRNRISFQADLLCASAMGIKHIVIKEGHDPTEGDQPVARSS
GDLDLATMLKCASMMNQGKDLAGEPLEGATDFDIGVYLELSDDVNLNRERAEYFIQLQSF
GVSSVTLGPTYDINIVEQFVPFAEQTGIKLLTSLMFLKSVTMIRYLNNLAGVPSVPQEFL
KKMMQSPDKKMSGVGVAAEFMQELAELSDGVVLLALGWGERITELLDLIER
>A0A0T0MNN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. Leaf395|TrEMBL
MSAAAVEPRTPGLHASTSRRAQAANDRPTISFELFPPRNPAAAPRLWATIQALESVHPDF
VSVTYGAAGKTRVTTRALVRRLLRETTLNPIAHLTCVGTSREEITTIVGEFLDEGLRSFL
ALRGDPPSDQSDWEAHPDGLQTASELVELLREIEAQRCADSPSQAVRARVRPLSVAVAAF
PRGNHATGGTRAQDVASLLAKQEAGADFAITQVFYDAEDYLGIVAEAREAGVTIPIIPGI
IPTTDPARLLRLQELTGVPVPHDLLDLLGSADDELDRHRRGIRASVDLVNGVLDGGAPGV
HLYTYNQHHAALDLLEGAHLDGGARTAPDLASWPQDTAPARPPRD
>A0A3M3GTX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. striafaciens|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDGKDDLRNLLAQYREAGIKRIVALRGDLPSGMGMASGELRHANDL
VTFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>Q07K33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas palustris (strain BisA53)|TrEMBL
MSDVLPAIATRPSISFEFFPPKTEEMERALWDSIKRLAPLHPEFVSVTYGAGGSTRERTH
STIARILAETDLTPAAHLTCVNAAKADIDEVVRRYHEIGVRHIVALRGDPTTGIGTPYVA
HPEGYQTSADLVASIKRNYPDIEVTVSAYPEKHPESRDLDADIDTLQAKIDAGATRAITQ
VFFDNDLYFRYVERVRARGITIPIVPGIMPLHNFRQAYGFVTRAGTTVPPWFAAQFEGLD
DDPETRKLVAATIAAGQVHKLAKHGVDSFHFYTMNRADLVFAISHLLGIRPTSAKKAA
>A0A1G8A7A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea jiangxiensis|TrEMBL
MATQRESAGAGSPRSCLADLLRRISYEVTPFPNTERNVLEHVPVTVPLTVTVTKAKGIDA
TLGLTERLVRHGYTVAPHLPARQFRDRQHVADVVARLREARVRSVFVVGGDAPRPAGEFE
DAYALLRAMREAHHPFEEVGIAGYPEGHPVVSREALELALKRKAPMATRVITQICFHAGT
TADWAAGIAAAGIGLPVHVGIPGPVNRHKLMRITANLGLGQSARFLRKHRSLLWRFLLPG
AYQPARLARELGLAVPRTGGNIRGLHIFTFDELSRTELWRRRLLESVSEKDDRS
>A0A1J4X5X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium CG1_02_64_396|TrEMBL
MQGPVRIPDLLAHRRVVTVEVKPPKGCDVGSALAEVAPIADRVDAVNITDSTLARMKISS
IALAAIIQERFGVNTVFNFTARDRNLIGLQSELLGGWALGCRNLLALTGDAVAIGDHPEA
KPVFEFNSVGLVKTVRTLNEGTDATGHPLEGKPHYGIGVAANPTAPKLESEIKRLAKKVE
AGAEFVMTQPVYEPQSLHRFLDLVAPLGIPVLLGILPLKSFKLARFLDEKVPGVHIPTDL
LARMNKGDPEAELAQGTQEAMAMLDAARDRVAGFHIMPAGHTGVVLALVDHLDRVGFRAL
PPPQ
>A0A072PGI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala aquamarina CBS 119918|TrEMBL
MHISKKLALAREANKPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
TLTMEMVKASQSQYGLETCMHLTCTDMERSQIDDALRCAYKAGCTNILALRGDPPRDQDK
WEVKAGGFRYAKDLVKYIKAKYGDHFDIGVAGYAEGCDDHRDVDLLVEHLKEKVDAGASF
VVTQMFYDVDIFLSWVNKCRARGIDVPIIPGIMPISTYAAFMRRADWTKCRVPPNWFEAL
NPVKNDDAAVRDIGKDLLAELCRRLLDAGILHLHFYTMNLAQSTRLILEELSLTPDTSGT
PLEKPLPWRQSLGLNRRDETVRPIFWRNRNTSYVARTADWDEFPNGRWGDSRSPAFGELD
AYDIGLKGTNEINIKLWGKPRSLREVTTLFTRFIEGDLDRLPWSEGGISSEADSIKANLL
HLNKNGFLTINSQPAVDGAPSSHPVYGWGPSGGWVYQKAYLELLIFPSIFDTVLQRLNAN
KNLTYYAVNQKGQLLTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WSKCYAPGSASRKLIEAIMSQCYLINIVNNDFHQTHEIFKIFDSLEVEDLDKAFEDTPAA
ESRNGERKVLNSGAKSPDIDQSVVNGDRGTIPFQTNGANHAN
>A7A5X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium adolescentis L2-32|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVNEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREKRPNLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCESRVPEKLAVLLDKWGSDTALLKEAGIAY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A255X3F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mandelii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2N6LHR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fischerella thermalis CCMEE 5318|TrEMBL
MLIFMLDSQNPTSLTSFRTAAKAGQFLITAEVAPPKGGNPEHMLKMAATLKGRVHAVNIT
DGSRAVLRMCPVVASAILLQHGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALTGD
PVKAGDHADCKGVFDLESVRLLQVIQKLNHGVDYNDKPLNDGALDLFPGAAVDPQCPSWS
GLQKRFERKLEAGAQFFQSQLITDFEILEKFMDKIAADCGKPILAGIFLLKSAKNALFIN
RCVPGVNIPQHIIDRLAQAKDPLEEGMKIAAEQVQIAQQLCQGVHMMAVKREDLIPQILE
MAGVTPVNQMVSL
>A0A7U4SDJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzicola|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPGYVSCTFGAGGSTLNYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
AALCERLMAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A6G2UFG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4931|TrEMBL
MALGTASTRTDHARTVREMLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A4R5L8M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia guartelaensis|TrEMBL
MSSLKQALNEGRFVCVLEVVPQQSPSRLAALEQIVQRGHLAGWPLLPAFADRVGLHSDLS
PLEGAGALGNPPSSLLHFSGKDRERADLLLQMESMKARGLEQLLLLSGDRLPGHIPGQAP
VRYLESVPALQIARAHYPDWLLGAALNPFKYREEEGGAQYLKAQKKLLAGADFLTLQLGF
DAAKHSEAQTWMRAQACMKPMLACVMRLTDKRASFLQAVPGVVITESMRELLGREQQASQ
AYASARSLERLALQIVGLQLMGYAGAHVSGVHTLDELLSLEQAIIEQRDSMTTLTDWAER
WHASWQMPGAPDVCFAPEAGAWEMGQSDVTATRRERLGYTLLSTVHGQFFSRTGWLSRAF
GWSVTRPIWKVGVAANALHAVERTVKRPLVGCDTCGRCRLQDTVYVCPETCPKGLANGPC
GGTRLNRCEFDDRECVHSVKYRIAKSADQLPVLAQTLIPCIEAENRHRSSWPEWFEAEDT
TQGL
>A0A671QGT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus anshuiensis|TrEMBL
RLKCGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHWFSLEFFPPRTASGAVNLIS
RFDRMGSGGPLFIDVTWHPSGDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKI
TAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLVKHIRCEFDDYFDICVAGYP
TGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAETFLRFVKDCRAIGITCPILPGIFP
IQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGIQQAVEMCKVLLASGEVPGL
HFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRT
QDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEELMNEGSVYEVFTNY
ITGQTNPSGHKVMCLPWNDDALAPETNLLKDELEKVNRRGILTINSQPNINGKPSSDPIV
GWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVQGKNITNAHEMQPNA
VTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWVKLYEDESPSRMIIQYIHDNYFL
VNLVDNDFPLDSCLWQVIEDMFALLDSPRATQEEGSQS
>A0A2E0KFY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. NAT40|TrEMBL
MDSTALQHSLNAGQPTITAEVMPPRGGDVRHTLAMAAALRGRVHAVNVTDGSRAVMRMSS
LAVCRLLLDHGMEPVLQIACRDRNRIALQADLLGAHALGIRNLLCLTGDPVTAGDQPKVR
PVNELESVRLLHQVTAFNRGEDPVKGDLADGPTALFAGAAADPHCSSQSGLLRRLERKRE
AGARFLQTQMVMDGAVLERFCTDLAAPLELPVLAGVFLLKSAKNAGFINRMVPGACIPDA
LIARLEAAEDPAAEGIAIAAEQVKRYMGIAQGVHLMAVRAEERIPLVLEQAGVSPVSV
>I0H111|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NBRC 102363 / NCIMB 12654 / NRRL B-3342 / UNCC 431)|TrEMBL
MSLGLPSRLPGTPSIGALIREPAPTFSFEFFPPKTRDGERLLWQAIRELESLRPSFVSIT
YGAGGTTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRNVIGRLAGAGIRNVLAVRG
DPPGDPTGEWVRHPEGVHYAEDLVRLIRESGDFSVGVAAFPYKHPRSADVESDTRDFIRK
CRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPIVPGVMPVTRMATIERSVQLSGAPFP
PALLRRFEAVAGDEAAVRELGVETCSEMCARLLAEGVPGIHFITLNRSTATREVWQRLAP
AEVAAAA
>A0A1L7V8Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium proliferatum (strain ET1)|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIHDIALLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDSEPIANGTAATAVAN
>A0A4R1HIX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiogranum longum|TrEMBL
MESQKKYPRVYSFEFFPPKTDEGAAKLRATRNELAKLKPRFFSVTFGAGGSTRERTFDTV
SEIQHDSDIEAAPHLSCVGSTKDNIREILDLYRKENIRHIVALRGDLPSGMGQPGEFRYA
NELVAFIRAETGDHFHIEVAAYPEFHPQAANADVDIDNFKRKVEAGADSAITQYFFNADA
YFGFVDACEERGIDIPVVPGIMPITNYTQLARFSDMCGAEIPRWIRKRLEACGDDRDAIR
AFGADVVTDMCQRLLDAGAPGLHFYTMNQAGPTRQIWERLNLG
>A0A423FCW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas canadensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQAHSFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISTMCEDLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A6P3I0H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bison bison bison|TrEMBL
MDRPKPKVFPVGHCCPSLGMRASEAGSGRLSVPPSISRNSAMVNEPRGNGSPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCPILPGIFPIQ
ASPALGPQCPSQAPGRGCPAHLLGLETKELHLPHAGVGRVPQRPLSKSPKEELLKMWGEE
LTSEESVFQVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINS
QPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVK
GENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESP
SRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>A0A1E4EWT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. SCN 68-21|TrEMBL
MSTPKISFEFFPPKTLEASFKLWEAARALAPLAPDFVSVTYGAGGTTRQLTHEAVTTINR
QFGLTVAAHLTCVEATRAETMEIVQSYADAGITEIVALRGDAPKGADRFTPHPDGFANSV
ELIEAIAARGDMTIRVGAYPEPHPDSRDGDADVTWLKRKLDAGATSAITQFFFEADTFFR
FRDKCAAAGIDAPIIPGLLPVQSWAGTKRFAATCNTTVPDWAEEAFQLAALDGPEATRQL
ATGLCVDLCEQLIAGGVDRLHFYTLNRPELTRDVCAALGVRPQPGLEAVA
>A0A8G7PKB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPH
>A0A6P3IBD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bison bison bison|TrEMBL
MDRPKPKVFPVGHCCPSLGMRASEAGSGRLSVPPSISRNSAMVNEPRGNGSPGPRWEGSS
SGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKG
HPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>A0A847QVG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epulopiscium sp|TrEMBL
MKIKDLFKTGPVISLEIFPPKPDMPIDTIFSTIHELADLHPGFISVTYGAGGSKKGHTVQ
IADAIQNKYGIETLAHLTCINSTKEEINDVLQRLQSVNVENILALRGDKPQDENLTNIKE
NQYKYAKNLIMHIQEFGGFSIGAACYPEYHIEAKDPISDLKNLKEKVNSGVDFLITQLFL
DNKFFYDFKEKLELMNISVPISAGIMPVINKKQIERITKLCGASIPVKFKRILDKYEDNP
SALKEAGIAYATEQIIDLLSSGVDGIHLYTMNRAEVARKIIEPISAIRKHLTTCS
>A0A7C6FQ69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Papillibacter sp|TrEMBL
MKVTDILDKRMAFSFEVFPPKTDKGMEKLCGKDGVLSKLMSLKPDYISCTYGAGGTNVGK
NLEVLDQIKAQGTIGVTHFTCVGNTREGIKEQLQTYLDHGIDHILALRGDLPFGWTGTGG
DLHYATELVKFIRDEFGDKFTIAVAGSPEGHISCRSIEADIAFLKQKQDEGADFIMTQLC
WDMDQFRWWMDAIQAAGITMPVDVGIMPVLDAAATINMALSRNGCVIPRPLAEIISKHWI
FPNPFAPNESEESIAQKKRDFKEAGIEYTIRLIDEYRVCGIHGIHLYALNKYDDVARLVK
ESGIKDM
>A0A2N2DZP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-12|TrEMBL
MIRDYLKNNVLITDGAMGTYYAQVTGKYNATPEFANLNEPEIIEKIHKEYISAGAKLIKT
NTFSANSMVLDIPFLQVKKIIQAGVQIANKAAQGKNIFVAASIGPLPETIDKIDLDYEVV
INEYKNIVDVFLDMKVKIIIFETFSDAHYLLETVKHIKAKDSSVFVVTQFAINPEGYTRR
GINSKSILKEVENYKNIDAYGFNCSVGPGHMYNYLKKKSFTGVMAVAPNAGYPEIIHERT
VYIQNPDYFAEKMKDISKLGVKILGGCCGTTPAHIEKMVEMIKPIPEICVDEQKATERIK
PYIYEKKTDGLTEKIKKGRFVIAVELDPPFNAEVELIMHNARICKDNGVDLITVADSPMG
RARVDSIMMAARIKREAGIEAMPHVCCRDRNLNALKSALLAGYIENIRNVLAVTGDPVAT
ADKNDIKEVFNLNSFKLMELISIMNKEQFSEEPLNIAGALNLNAVKPEIELGRMLKKIDR
GANFFLTQPIYDEAIINLLSGIEEQNRMKILGGIMPVVSYRNAQFLNNEVAGIRIPEEII
AKFNPDMRREEAEDLGIEIAVDIAKRMKDRVGGFYFITPFNRVEMIIKIIRRL
>A0A7W6JCP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas lenta|TrEMBL
MTAPALSLAEARALLLSPLGPVARAGQDASRPRVSFEFFPPKTDEAEANLWKAVTRLAPL
QPDFVSVTYGAGGSTRERTHRTVQRILGETSLTPAAHLTCVEASRDEVDAVIDGYHAAGV
RHIVALRGDPPGSNGIGGVYAPRADGYANATELTAAVARRGGFEISVGCYPEGHPESPSA
AHDTDVLKAKVDAGATRAISQFFFDIDAFLRFRDRVRAAGVEVPLIPGIMPVTNFAGLKR
MSATCGAAVPGWLAAHFDGLDDDPETRKLIAASVAAETCARLQEEGFADFHFYTLNRADL
VYAICRVLGVREQKAEA
>A0A6J4R107|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Rubrobacteraceae bacterium|TrEMBL
MQDRRSGLVEALRRPRYEVIPLPGVEDGVAEHVPRHVKITVTASPKKGLEPTLELAERLS
GEGFEVAPHLSARLIRDRAQLGEILARLRGAGIRDVFVVAGDAPEPAGEFEGSAALLGAM
AEIGHGLEDVGITGYPESHPLISDEATIQAMYQKEPHATYITSQICFDTDTINNWVLRVR
RRGVGLPIYVGMPGAVSMAKLVRISSNIGLGESARFLQKYGNWFWRMFMPGGYSPDALVE
GVSDSLAHPERKVSGFHIYTFNEVQKTEAWRLAALERAGAKAHERHKEPTA
>E6J1D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus anginosus F0211|TrEMBL
MSIQSPSLSFEVFPPNPAVGNEKIMAALKEMQDLVPHFISVTASNNKFNIEETTVRLADF
IRNDLHIPTIAHLPAVYLTKEMVTETLTALDKVGVHKVLALRGDILPDVEPQKDFVYATD
LIEYIKKEAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYD
FQDKCILAGIEVPIHAGIMPILNRNQVLRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSDTAHRIYQATHTFFNK
>A0A2W6AW95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
MRDALAAGPTFSFEFFPPKDERGEAALWRALQALEPLDPSFVSVTYGAGGSTRAGTVQMT
EQIAGRTSMLPMAHLTVVDHSVEELRDVVDEYAAAGVRNLLVLRGDPPGDPRGKWATHPD
GLQYAAELVSLVAERGSFCIGVAAHPTGHPRSSDIGEDARRFVEKVRAGADFAITQMFFH
VEDYVRLRDRVAALGCNVPIIPEIMPVTSIGQIERFGILAGEVFPADLAARLLAVGDDAE
AVRTIGVDAATSLCDSLLAEGAPGLHFITLNGSRATLAVWSNLGLRVGAHG
>A0A1I2U080|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter chinhatensis|TrEMBL
MKVTDHFKNANGKTLFTFEILPPLKGENMKTLFNHIDPLMEFNPPFIDVTYHREEYVYKQ
RENGLLEKRTTRKRPGTVGICAAIQNHYRVDTVPHLICGGFNKEETENALIDLHFLGIDN
VLALRGDCVKSEQRFVPEPGGHNYATELIEQVANMNNGVYLDDEQAYHNGTDFCIGVAGY
PEKHFEAPNLKSDLRWLKKKVEMGADYIVTQMFFDNQKYFDFVNRCREEGITVPIIPGLK
PMTTKTQLTLLPSLFHIEIPCALAEAIEDCPDNKAAAQVGVEWAIQQSKELMAFGVPCLH
YYSMGKSDSVRKVAEALF
>T0XVT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospirillum sp. Group IV 'UBA BS'|TrEMBL
MEFARPFGVPVICGIILLKSPAMARYLNEKVPGIRVPDSLIARLETCSREERIEEGIRIA
AETIKSVSSLVNGVHIMTVGAEEPDPRHSRSGRDLTXPVDSPSPPTIPGLLRRTKTGSPL
FPW
>A0A851NZ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penelope pileata|TrEMBL
MVNETQHPCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLRERMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVHGFNYAVDL
VKHIRSEFDDYFDICVAGYPTGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETSLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPVVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYETRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7L3Y2W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calonectris borealis|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDN
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPDAESYEADLRYLKEKVSAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAASMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEDFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A812MPK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiodinium sp. KB8|TrEMBL
MAARIDELMAAHSGDAPWVAFEYYPPRTEDGVNNLKKKMPRFKACPFPRPRVRLKEPLYI
DMTFGAGGSTSDLTLDLCKEAKEKIYEALEGAKAAGIRNIVERWEAVEGGFTCALDLTKH
IVKTYGKDQFCISTAGYPEGHPGAIKKVAEGQELSDKEKRRVVSLEDGDYVCSDADFAKE
MEYLKAKVDAGASLIITQMFFDVDVFADFLEACKEYGITVPVIPGLMLVQNAGGFGRMTA
FCKTRVPASIREGLEAVKEDDAAVKQFGIDLGAKMCEQLMALGCKGLHFYTLNLEKVTFG
VMRKLGLFDEDAAAAAAAAAEPAAAASAGAASAHYVARGWGTRLAWRRLQWLRAPAAFRT
RLAPAAAEPRVCGAHPATRIRLAVRPQLPGRPSEPPRGSEGSRASFAQTRGRPVRVADAA
ANAMALGGKRLLRAGALFVTFAGVERAITLARGGKAESWNFLTAGALTSGLFGFASGQLR
RGLLIGGFLSLAGLPVYLVVTGGGIDAAAERLALAIGVQVPAPAPGDSPRSPGATAPGGS
MPLSENGPAAPPTATGECDASAPAARGVVGADQGDEDQGTEAPRA
>A0A327LSK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium AsT-22|TrEMBL
MMAPKVSFEFFPPQNLEGSFRLWDTIHALAPLDPRFVSVTYGAGGTTRDLTRDAVRTINK
ATGLNVAAHLTCVDATREETLAIAESYAEAGVTEIVALRGDPPKGSGRFVPHPEGFAHSV
ELIEALAATGKFTIRVGAYPDVHPEAKNPQADIDWLKAKLDAGADEAITQFFFETESFLR
FRDACAKAGIEKAVVPGIVPIENWKGVRNFAFRCGASVPAWLDDAFAKAERDGREDLLAT
ALCTEMCSELIDEGVDALHFYTLNRPELTRDVCHALGVVPRVQLENVA
>A0A0E3KU66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium ulcerans|TrEMBL
MSASHIPAAYQRSITEVLKMPSPGRVPFSVEFMPPRDTAAEQRLWKAAEAFHDLGTAFVS
VTYGAGGSSRERTMRVAHKLSKHPLTTLVHLTLVEHTEAELVEILDDYAAHGLSNLLALR
GDPPGTNPMAEWVATPGGLEYASELIELTKKNPKTSHFHVGIASFPEGHYRAPTLEADTE
FTLQKLRAGAEFSITQMFFDIEHFLRLRDRLATADTEHGCKPIIPGLMPITSIRSVRRQM
ELAGASLPRELEKQLLDAAKGDEESHKEDVREVGIELTTQMAEKLIAEGVPDIHFMTMNY
VRATQEVLHNLGMAPAWGTDHGHDAVR
>A0A4P6EZ18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus protaetiae|TrEMBL
MLKEKILNRQAGIVTYGITPPKSAYSPEKIMEISQKQYERLKDLDIDGLILYDVQDEADR
TDEERPFPYLNTLEPTHYCKTYLSQWQVPKIIYRCVGNNSEQELEDWLRQDAEEDRFSVF
VGTSSSKQQTTIKLPDAYDMSRKLNDRLMLGGVVIPERHMKKNDEHIRITEKVNGGCRFF
VSQATFNVEASKNMLSDYYYHCLENRLEMVPILFNLAPCGSQKTLEFMKWLGISIPKWLE
NDLLNSNDILDKSVSLSLKIFEELFEFGLEKGIPIGCSIESVSTRKVEIEASVQLVKDIK
SIIDRKLGVYSAV
>A0A6J4PK59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Rubellimicrobium sp|TrEMBL
RDRVGGPAEGRGDRPARPYRHRGSRQAPDPHQVRDRLRRGALAPGAAEARDGRDEAPAAL
RARRGRGRACRPQGGEFGLWHRAGAYLPPGWHRHRRQLGQCPHRADARPRRERI
>A7TTE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)|TrEMBL
MTVWIACIKQPSRPSSMSRGTQEAATPQTETRMQQTAARRPTRSCFTAQSVLGLETCMHL
TCTNMSLAAIDAALEQAHASGCHNILALRGDPPRGQPSTASSSESGSSGGGNGSSDGDCN
FKFAAQLVRYIRSKYGNHFAIGVAGYPEGDGEQADQRLLLQHLKEKVECGADFIITQMFY
DVDNFLRWVHGLREVGVTVPIIPGIMPISTYAAFLRRCSWCGVRVPDNFLQRLAPVSDDD
ELVREIGTQLVVDMCRRLLESGVVSHLHLYTMNLERPPLVILERLGLLPEASAEQSIDTF
TNEPPAVVPWRRSLNPQRRNEEVRPIFWKSRPYSYVARTSQWAADEFPNGRFGDSSSPAF
GDLDLCGSTLLRQSAQRSLELWAMPSSIRDVAMLVVAYLQGELRCLPWSDTPVSSEVDVI
RRQLIALNEQQLIVTINSQPQVNGLRSNVKGFGWGPSDGYVYQKQYLEFLLPRARFERLQ
QELSKTNETTSSLTYLAADSHGGWWSNQPDGAKATAVTWGVFPGREVLQPTIVEKISFLA
WRDEFYRILQDWRDIFVHASPDGDQCDNGSAQRENPSAKLMQLMIDDYVLVNLIDNDFVS
VDDKIFELLMKI
>A0A6N2U439|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium adolescentis|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLHGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVDEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREKRPNLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCQSRVPEKLSVLLDKWGGDTALLKEAGITY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A835KK14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Digitaria exilis|TrEMBL
MKVIEKIQKAAADGRTVFSFEYFPPKTDDGVDNLLERMDRMVAYGPTFCDITWGAGGSTA
DTTLKIAKSMQNLVCVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFSCALNLVKHIKDKYDDYFGITVAGYPEAHPDEIKADGRAPPEAYNRDLEYLK
RKVDAGADFIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYNGFKRMTTFCKTK
IPAEIIAALDPIKENDEAVKNYGIQLGTDMCKKILASGIKTLHLYTLNMDKSALAILMNL
GLIEESKISRTLPWRPPTNVFRVKEDVRPIFWANRPKSYITRTAHWNQYPHGRWGDSGNK
YAQLPDDMFTRPSGRSKKLNEEWVAPLKSAEDIKERFTNFYQGKLTSFPWSESYGLQQKI
IDDQLVKINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCTEEKLGQLI
KKIKEAFPSLTYMALDKNGKSFTNIPANAVNAVTWGVFPGKEIIQPTVVESASFKFWMEE
AFGIWAHLFGKDDSSPLKTVLHDTPKLEHSTVSYSRVMRMKNAIKRATCSSRFFKLLVYA
ICLSTVTVVHYYH
>A0A8G1VR23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus piperis CBS 112811|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDVQDPARDLPYL
IEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPQVLSKLEEVKHDDDAVKRIGVDIITDLVYGIRDLVSPGLRGFHFYTLNLEKT
VSFILERCELIPPYTEIDDSDALVDGGNLSAMDSSSYIAPNGAPIRTLASRRSSVSSIPH
NRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEEDSNGLNAETAVIQPELLTLIDKKGWWTLASQPALNGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNPDDPDPIDIN
PANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDETK
NDVWLVCVVGQEFGAGTEAGSEEEEDEKKWMWRELANSQ
>A0A6B3PJ74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO1F9|TrEMBL
MNRFRNAVKSGEFLVTAEVAPPKGADPAHMIEMASTLKGRVHAVNVTDGSRAVLRMSSLA
ASIILKNNGIDPICQVACRDRNRIGLQADLMGASALGLHNILALTGDPVKAGDHKDARSV
FDMESVRLLQMIAKLNQGIDWNEKTLPDGATDLFVGAAVDPQSPSWSGLKKRFERKLLAG
CQFFQSQLISDFDKLEKFMNQIAVESNKPILAGIFLLKSAKNAAFINKYVPGVDIPEHII
NRLAKAEKPLEEGIKIAAEQVQIASKICHGVHLMAIKREDLIPRILDMAEISPIEQ
>A0A231P601|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sp. MES5|TrEMBL
MHIGDSIRAAKKPFFSLEFFPPSDEGNLPGFFETVEKLRALAPLFVSITYGAGGGKQRNT
LAVTAELAQRGLNTMAHLTCVGAEPESISAYLAELRAAGVDNVLALRGDPPAGQEWDWST
GYFRHASDLVAFARRQQPYMGIGVAAYPAPHPESNSIALDRFYTADKMRSGADFAVTQLF
FDAREYADLLEHLRGRGIHTPVIPGILPIQSFDSLRRVLSLCGANIPGKLYLDLESANAK
GGAEAVREVGLEFAVRQIRFLLENGAPGIHLYTLNKADMCLKLAEESGLL
>A0A3M5P5V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas viridiflava|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKADLRGLLGQYKEAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITEMCERLLQGGAPGLHFYTLNQADPSLAVWNNLKLPR
>A0A0Q8RIN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. Root198D2|TrEMBL
MANHNFSIEFFPPKTAEGTEKLRLVRAKLSELHPKYFSVTFGAGGSTQQGTLDTVLEIMA
AGEEAAPHLSCIGGTRESIRTILQQYKAHGIKRLVALRGDLPSGYGMSGEFRYANELVEF
VRAETGDWFHIEVAAYPEVHPQARSPQDDMQAFVRKVNAGADAAITQYFYNADAYFHFVD
AAQKAGVNVPVVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VSDLCERLLAGGAPGLHFYSMNQAVATTALWSRLVSPQ
>A0A366X9L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria sp. A3M17|TrEMBL
MTKPEISFEFFPPKTLEASFRLWDTVQTLAPLEPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLPVAAHLTCVDASRQETLEIADTFARAGVQDIVALRGDPPAGQNRFQPHPDGFANSV
ELISALAETEMFNIRVGAYPDIHPEAQNARTDIDWLKAKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGILPIENWKGARNFAKRCGTRIPQWVEQAFEKAVRDDREDLLAT
ALCTELCSDLIDGGVDKLHFYTLNRPELTRDVCFALGITPKADLQNVA
>A0A128ECP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter geochelonis|TrEMBL
MLIEKLKSNQAGILLYGLTPPKSNLDNDEIKRISSLQKDRINSLQIDGIILYDLQDESAR
TSQKRTFEFIHTIDPYVYYTDFLHVTKPAIIYRAVGKYKSDEFSDVLTRCKGSNFATVFV
GASSKNQNVNLKLDEAYRIKERIAPNLALGGICIPERHASKANEHLKVASKTSQGCEFFI
TQAVYNVENAKNFIDDYAKMGVKKVPIIFTFTPCGSLKTLEFMKWLGISVPPFLETRLKN
SVDILQSSVSLSLEMFEFLYKYSQAKGVSIGANVESISTRKVEIQASIELLNGIKKIIDK
KF
>A0A064CWP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii MGH 56|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1Q7WE22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catenulispora sp. 13_1_20CM_3_70_7|TrEMBL
MALGLPSVRPDRAATVRELLARGERSYSFEFFPPRSDAQEEQLWRALRRLEGYSPTFVSV
TYGAGGTTRMKTVETTERIAADTTLTPVGHLTAVNHSVAELRHVVGQYADAGVRNILALR
GDPPGDPLGEWTPHPDGLSYASDLVQLVRDSGDFCVGVAAFPEMHPRSPDWDSDVARFVE
KCRRGADFAITQMFFLTDDYLRLRDRVAAAGCDVPILPGVMPVTNVAQIKRITGLTGQAF
PAELENALLAVDGDKAAVRAVGVEWTTRMCERLLAEGVPGLHFITLNMSTATLEIYRNLG
LDRRQENAAYLKVPA
>A0A415FUD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium adolescentis|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVDEALDLFDQAKVSGVLALRGDRVEGAKPAGVFDHASDLAA
YIREKRPNLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCESRVPEKLAVLLDKWGSDTALLKEAGIAY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A350ATW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MTNHSIQQRLEDTAPLFSIEFFPPKSEKSAEQLLRTAETLRAYSPDFASITYGAGGSTRS
RTLKYARSLSEDYGYNVMPHLTCVGHSRDELKGIISEFKEAGLSQIMALRGDPPKGETNF
TPHPDGLSYANELVSLIDEVYPECVLGVAGYPEKHPEAQSLELDLLNLRRKVDAGADFVT
TQLFFDNRKYFAFVDNCIRAGIAVPVLPGLMSIASRDQAIRFCEMCGTSIPAELDALLLA
AGDDKEAVEAVGIEWSYMQARELLEKGAPGIHLYIMNRAEPAIALMDKLQAAGFYK
>A0A2M7DUQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG02_land_8_20_14_3_00_37_13|TrEMBL
MKLKDLFKSGKFAVTSEIGPPKGCHIDNVLHEAETFLKGRVAAINVTDNQSSVMRFGSLA
TCHLLKDRGMEPVFQVVCRDRNRIALQSDILSAAGLGIENLLLLTGDHTKLGDHPGAKPV
FDLDAVSLIHTVKKLEQGEDLAGNKLEGEPP
>A0A2K9LMA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ketobacter alkanivorans|TrEMBL
MDSQKQYEKRFSFEFFPPKTDAGVEKLNGVQQKLAEKKPSFFSVTYGAGGSTRDRTFDTV
MNVKAKTGIDAAPHLSCVGDTKAQLAELLGQYKSNGINRIVTLRGDLPSGMGASLGELKY
ASDLVGFIREQTGDHFHLEVAAYPEMHPQAKSMDADLQAFKTKVEAGADSAITQYFFNVD
AYKFFVDSCEKMGLDLPIYPGIMPIINYDNLMRFSSMCGAEIPRFIRMRMEAFRGDEQSI
KQLGEEIVTSLCEELLAMGAPGIHFYTMNQSEPTLAIWNNLNL
>A0A1W1IDZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus pasteurii|TrEMBL
MKIESKFQKKKPVLSFEIFPPKRDKAIQNIDETLAILSELNPDFISVTFGAGGSHTNNQT
VELAKRIKHQYGIDPLVHLTCLNHSKFEICELLEELRAADIDSILALRGDTNPAVEAKKD
FRYASDLVKFIRQYGDFSISGACYPECHTESKNKVEDIAHLKEKVDSGVQHLISQLFFDN
NAFYSFQEHIQIAGMHVPVEAGIMPVINKAQIERMVTLCGASLPEKFSRVMHKYEDNKEA
LFDAGMAYAINQIVDLLAHDVDGIHIYTMNNPIVAKRICDGIKNLI
>A0A4Z0V8G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duncaniella freteri|TrEMBL
MRVIDQLKATQGHTAFSFEILPPLKGNDITRVYSIIDKLREFDPKYINITSHHSEVQYQE
MPDGSYIKKKIRKRPGSVAIASAIQNKYGITAVPHIICKGFTRDETEYALIDLNFLGVHD
LLLLQGDAKGPDKSADPTKINQHATDLQQQVNDFNRGIYADGETFEANATPFSYGMACYP
EKHESAPNMESDIRYARMKVEQGASYLVTQMFFDNQKYYDFVTRCRAEGITVPIIPGIKP
IVLRNQLNVLPRVFRTDIPEPFAIELARCSTDEQAKETGIEWSIAQCRDLIAHGVPSIHF
YTLMATDSVRRIAKEIY
>A0A839EII3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium myrsinacearum|TrEMBL
MTKIAASIEVAARQAIDSQDLPGLFPEGTRVYITDMGTDGVDTLTAAAKRIHDLGYKPVP
HIASRRLGTRAALETRIRRAAEEAGVTDVLVIGGGLERQAGDFSSTMEVLETGFFDKYGI
TEMGVAGHPEGSPEFSEAVALEALRLKKNFGERTGARLRVVTQFGFDADRFIRYSESLRE
HGVDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNALSLTALATSHSPEGVVGPIE
QHVINNPASAIKQIHIFPFGGLKKSSEWLVDRGSWSVASAQYASAAAN
>A0A8F7ZKA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylovirgula sp. HY1|TrEMBL
MDLAASSLPRASHTTCSGMDVSFEFFPPQTEEMEKILWASIERLGPLDPSFVSVTYGAGG
KTRERTHATVARILKETQIKPAAHLTCVGASCAEVDSVARDYWDIGVRHIVALRGDPQNG
PGTAFAAHPEGYENSTALVAGLKKLADFDITVSAYPEGHPESPSVDRDIDVLKAKIDAGA
TRAITQFFFENDVYLRFLDKVRAKGITIPILPGIVPVQNFKQTANFARRAGASIPQWLAD
RFEGLDDDVTTRRLIAATITAEQVFDLVDQGIHHFHFYTMNRADLVYAICHLLGVRPKHE
MAAM
>A0A663F8I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquila chrysaetos chrysaetos|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQESGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRYLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VEQAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSQTQQ
>A0A6A5Z1V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lophiotrema nucula|TrEMBL
MHISEKLAQARAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDVTWGAGGRLS
SLTCEMVKVAQSVYGLETCMHLTCTDMEKSKIDEALKDAYNSGCTNILALRGDPPREKEK
WEATAGGFRYARDLVKYIRDRYGNHFDIGVAGYSEGSEDNEDVDQLIDHLKEKVDAGATF
IVTQMFYCTDTFLAWVDKVRAKGIDIPIIPGIMPIHTHAAFLRRATWTRCKIPEEWTAAL
DPVKNDDAEVREVGKGLVANMCRRLIDAGITHLHFYTMNLAQTTRMVLEELELLPDMESP
LDRPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDARSPAFGELDS
YGVGLKGTNEQNIKLWGKPTSVKDISELFVRYMSGKLDALPWSEQPISQEAETIQQDLVE
LNKRGFLTINSQPAVNGAKSSDAVYGWGPRNGYVYQKAYLEVLISPELIAEVITRIERNP
ELTFYAVNKEGDLKTNAPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQDW
SRCYSSASPSRYVIEDIMDTWYLVNIVHNDFHVAHGIFSLFDNLQVNDMEKQLHPDGILN
GTTNGDSRTKVNGEKSKVGVAVDAVKSTASAVTNGLNGLKLTN
>Q133H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas palustris (strain BisB5)|TrEMBL
MSDVLQHIPAISFEFFPPKTDEMERTLWQAISRLAPLTPRFVSVTYGAGGSTRERTHSTI
ARILRETHLTPAAHLTCVDAPCADVDEVVERYYDIGVRHIVALRGDPSSGLGGAYTPHPQ
GYRSSADLVASIKRRHPDIEVTVSAYPEKHPESTGFDADLDMLQAKVDAGATRAITQFFF
DNDLYFRYLDRVRARGIDIPIVPGILPVQNFKQASNFATRAGASVPDWLAKQFEGLDDDP
DTRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGLRPQAAQKAA
>A0A416PAT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. AF22-28AC|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTSSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>F0SDG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudopedobacter saltans (strain ATCC 51119 / DSM 12145 / JCM 21818 / CCUG 39354 / LMG 10337 / NBRC 100064 / NCIMB 13643)|TrEMBL
MKITDHIKNANGKTLFSFELLPPAKGQSIQWIYDAIEPLLDFKPPFIDVTSLREDYIYKQ
KDNGLLEKLSYRKRPGTIAICAAILNKYKVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKADGSFIPTPNGHAYASDLLQQVKNHNAGKFLHEDIEVEYKSDFCVGVAGY
PEKHFEAPNMETDFRYLKQKVDMGADFIVTQMFFDNQKYFDFVNKCREHGINIPIIPGLK
PISALSQLINLPKIFHIDLPQDLVEAVQSCKTTKDVKQIGTEFMIQQCKELIKFGAPVLH
FYTMGRPEQTRQIAEAVF
>A0A024FEW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella sp. PG-2|TrEMBL
MVKPKHRTINMKVTEHIKRANGKTLFSFEIIPPKKGNSIQQLYNNIDPLMEFNPPFIDVT
TSREEYIYIEKDGLLDQKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLV
DCHYLGIDNVMALRGDAMKHQKYFEASNGGHQYAKDLVGQIQNLNKGQYLHDVIEVDDRA
DFCIGVAGYPEKHIEAPSLKTDLKRLKEKVDKGADYVVTQMFFDNEKYFKFVKAAKEEGI
NVPIIPGIKPIAVKRHLQLLPQVFKIDLPEELIEAVDNCKTNQQVRQVGVEWAIAQSKEL
QKAGVPVLHYYSMGKSDNVKAIASALF
>A0A653QK66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. 9AX|TrEMBL
MSPPSLIDTHPNLSDAAPVALSYELFPPRSPAAAETLWTTIRELETTGPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIIGELLDIGVRGILALRGDLPKD
GGQPAAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEEHDVEVLL
AKQRSGADFAITQVFFETEQYADLLARARRAGVTIPIIPGVMPLTSLRRLTRLGELAGVE
PAPRLMERLAAADNDIERLHIGVDATVDLANAALDAGAPGIHLYTFNEHQSALEVLDKLA
LPRHQRSGARHDARARRQLAS
>A0A495BN63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vogesella indigofera|TrEMBL
MTERNRTFSFEFFPPRTPEGVAKLRTTRQQLAQFKPEFFSVTFGAGGTTRDGTLSTVLEI
RNEGYAAAPHLSCIGSTRDNIRSILNEYRNHGIRHIVALRGDMPSGMVEAGEFRYANELV
AFIREEHGDHFHIEVAAYPEFHPQAKSAEDDINNFVRKVKAGANSAMTQYFFNADSYFRF
VDEVQARGVDIPIVPGIMPIANFGQLCRFSDMCGAEVPRWLRLRMQAYMDDSASIRALGL
DVVTELCDRLLANGAPGLHFYTLNQAGTVSTIWQRLGL
>A0A1Y6F595|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia lucknowensis|TrEMBL
MLDDNLRASRKTADQRPPLQISFEFFPPKTDAMEERFWDSIAKLAPLSPRFVSVTYGAGG
STRERTLRMVSRITSDTGVPAAAHLTCVGATRDEVDEVVRGYKAVGVNSIVALRGDPPEG
VGQPFTPHPQGYQNAADLVAGIRKLGDFDISVAAYPEKHPQSADWQADIDNLKRKIDAGA
NRAITQMFFSNGDYLRYVERARKAGITAPIVPGIQPIHSFKQISGFAARCGASIPGWLAE
RFDGLDDDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRP
>A0A1M6CZS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasporobacterium paucivorans DSM 15970|TrEMBL
MRITELFQRGEFVVTAEVGPPKGFHIEHLIEEANTYLKDRVHAVNVTDNQSSVMRLGSLA
TCKVLKDQGHNSIFQITCRDRNRIALQSDILSAALLGIDNLLLLTGDYTTFGDNPQAKPV
FDLDSVSLLHTVKRLEEGFDLAGNPLDGEPPKFAKGAVVSPCSDSVDIQLAKMEQKVKAG
AEYFQTQGVYEPEKFIQFMEKAKQFGVPVQLGIIIPKNVGMCRYMNANVAGVHVPDEMIA
ELQQDKEKTKAGITGVEISARIIRECKDYCQGVHIMALGWESKVPDILDLAGIAPVSK
>A0A173UVH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia faecis|TrEMBL
MKISDACNHKKSLSFEIFPPKKDSELKNIDATLDVLCELQPDFISVTFGAGGSLNCNRTI
ELAKKIKQNYHVEPVVHLTCLHYNRAEIDEFARILTAEGIQNVLALRGDRNPDLTEKDDF
KHASDLISYLKPKGDFCFLGACYPECHPESANKIEEIRHLKEKVNAGAEVLLSQLFFDNT
QFYRFVEDCRIADINVPIVPGIMPVINAAQIKRMITMCGASFPERFQKIIHRFEDSKAAL
FDAGMSYALSQIIDLLANDTDGIHLYTMNNPVVARRICEGIQHII
>A0A345DAV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ephemeroptericola cinctiostellae|TrEMBL
MTIQTPISFEFFPPKTIEGQQKLEHTINLLTPYKPQFFSCTYGAGGSTQDGTFKTIAHIR
SLGHDAAPHLSCIGSTRDNMANILQDLKRQGVRRIVALRGDLPSGMGGTGELHYASDLVA
FIREETGDHFHIEVAAYPEYHPQARSPADDLKHFVHKMNAGANSAITQYFYNADAYETFV
NAARAAGVTAPIVPGIMPITNYSQLARFSDVCGAELPRWVRLKLASFGDDKASIIAFGQD
VVTQLCSRLIDLGAPALHFYTLNQAKPSLAVIDAL
>A0A1F9B4Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_53_10|TrEMBL
MKAGSHLETILEKGLFAVTGELGPPKGNNLEVIKKKVDLLRGYVDAVNVTDNQTAIVRMS
SIAASSHLVRMGLEPVMQMVTRDRNRIAIQSDIFGATSLGIKNMLCLTGDHHTFGNQVDA
KNVHDLDSVQLIDCVRTLRDKGTLLGGEEKIDGEIKLFIGAAENPFGDPFEFRAIRLGKK
VAAGVNFIQTQCIYDMNRFKEWMKMVRDRGLHEKVHILAGVTPLKSGGMARYMAKNVSGI
IIPDEIIDRIVKAPKPAEEGIKFCVEQIQELKEIEGVHGVHIMAIEWEQMISRITEMAGL
LPRPNVD
>A0A0F2N9P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium BRH_c16a|TrEMBL
MKTESRLEKILAAGHLAVTSECGPPRGCQPAHLIEKAKYLEGIVDAVNVTDNQTAMVRMS
SLAASFIIKQQGLNPLFQVTCRDRNRLAMQADIIGAYSMGIDTMLCLSGDHTKFGDHPMA
MNVHDIDSIQMIQMVKDMRDKGIFQGGAEIKGAPKMFIGAAANPFADPFELRVMRLAKKI
AAGADFIQTQCIFNVEKFERWMEGVREKGLHKKCYILAGVTPCKSLGAAKYMANRVPGMD
VPKEIVDRMASVPKEKQAEEGVTICVETIERLKKIEGVAGIHIMAIEWEEKVQEICERAG
LLPRPQV
>X6IES2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L2C066B000|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTIKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHKDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A0M6WHW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia faecis|TrEMBL
MKISDACNHKKSLSFEIFPPKKDSELKNIDATLDVLCELQPDFISVTFGAGGSLNCNRTI
ELAKKIKQNYHVEPVVHLTCLHYNRAEIDEFARILTAEGIQNVLALRGDRNPDLTEKDDF
KHASDLISYLKPKGDFCFLGACYPECHPESANKIEEIRHLKEKVNAGAEVLLSQLFFDNT
QFYRFVEDCRIADINVPIVPGIMPVINAAQIKRMITMCGASFPERFQKIIHKFEDNKAAL
FDAGMSYALSQIIDLLANDTDGIHLYTMNNPVVARRICEGIQHII
>A0A7J2KFK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidilobales archaeon|TrEMBL
MVRVYSELMKALLSGKFVYTAEIEAGKTANLEGIIEKAKRLKGYVTAINITDNPGACAHM
NPLIPSYVIQRDVGIETVYQLTCRDRNRLALTS
>A0A8F7PG27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. TNS106|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPEGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTPRTLHTSIKLSGAPAPRRLLDRLEPLA
DDPKAFRAAGIDAVTELGERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>S0G4P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotignum phosphitoxidans DSM 13687|TrEMBL
MNIMEKIKNHGLLFDGAMGSILISKGLAGNEAAEAWNIQHPDIIRQIHTDYIAAGADVVS
ANTYGASLLKLEKTGMSKDFEMLNREGVRLAKTAGHSDHYVAADFGAMGDMLAPAGPVSF
ETAKNCFVRQAEILEDEGVDLFLVETVFDLNAGLCAVQAIQSVSGKPVFCSLTFKETPKG
FYTIFGNAPEHSMKVLADHGVSAVGANCSLGSDAMVRLADQIRQSVDIPVIIQPNAGMPE
ITADNHTVYPETDDLFAANMKKIRDLGVEIIGGCCGTTPETIRKIRALL
>A0A178MU11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum marisnigri|TrEMBL
MTSELPIAAASKRPVSVSFEFFPPKTEKMQQALWDCVQRLEPLAPLFVSVTYGAGGTTRE
RTHDTVVRIARETKLKPAAHLTCVGHSRGEVDDIARRYWDEGIRHIVALRGDMPDGAPYA
AHPDGYAYAVDLVAGLKRIADFEISVAAYPEKHPDAPDAGFDLDNLKRKIDAGASRAISQ
YFFDPSVFLAFRERCAKAGITVPVLPGILPVTNFAQVQKFSAACGASVPEWMADLFAGLD
DDPETRRLVAATVAAEQCRILAAEGVDNFHFYTLNRADLAYAISHILGVRPRA
>A0A2S5XU07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter rathayi|TrEMBL
MSRARFEIIPAEDIGERAMRAFPDPSAVTLTVTSLPKHGTGRTVDCAVELAGRGFRVVPH
LAARNVEGRGALERVLRRMDAAGIDEAFVISGDATSAAGSYSTSLELIRDAREIAPGLAL
DIAGYPEGHPRLSDESIDRHLRERAPFIRSIVTQMCFDVDAVVRYADRLRAQGVTADLWA
GVPGPVERSRLLTLGARIGVGSSLGFLRRSTSVAGGLLRGRRFDPSAFVARLESAAGERL
AGLHVYTFNELDSLAAFA
>A9DBZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea phototrophica (strain DSM 17068 / NCIMB 14078 / DFL-43)|TrEMBL
MNQADTNPNDPSALLEPLPGHSSLGRLERILRRGEFAVTAELNPPDSANPQDVYERAAIF
DGWVDGINAVDASGANAHMSSVGICALLTRMGYAPIMQISCRDKNRIAIQGDVLGASAMG
VQNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRIMRDNSKFLSGRKLTSPPTVFLGA
AINPFAPPQDFRVHRLAKKIAAGAQFVQSQYCYDVPMFRNYMQQVVPEHGNIRNYMQQVR
DMGLDKECFILCGVGPLASARTARWMRSNVPGVHIPDTIIERLEGAKDQKAEGKRICIDI
INEVKEIEGVSGIHVMAYRQEEFVAEIVHESGVLKGRRPWTKEPTSMDEMVAARMEEILE
EPKHLLHEMAGAASEPDTQE
>A0A0Q8R9R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Root720|TrEMBL
MPGGLPAAARDDDGPPVRERVAALARTASFEVSARDDAAIEAAASLVAPGGRVSITWLPR
DGDDDRIGAARALRRIGLEPMPHIAARMIEDEAHLGRLIGRLCDEAGVSQLLVIGGDAKQ
PRGPFTASADLLASPAFAHPSLRRIALGGYPEGHPAVGEADLAAALDAKIAAVEALGLTP
EVITQLCFDSDPMLAWTRAFRARHRQVPVRLGIAGPASIRTLMRFARICGVGASARAIVS
RGASIARLLTEAAPDPILRDLAETPDIDALGPVGIHLFPFGGFERTARWIGAVAAGRIRL
RQSDSGFQVEG
>E3S600|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenophora teres f. teres (strain 0-1)|TrEMBL
MEKITDKINSLPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCIGVAAYPEGHSDQSHPEHQDPLSDL
PYLVEKTKAGADFIMTQLFYDVQAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHARLPTEMLSRLDAVKSDDELVKQVGVQIMDEMVEHIKARPNSCRRGFHFYTLNL
EKTVSHVVEDTHLIPTTIMDDEEVIVETTPAINLEPPPNGLMAHRRRSSAVNSGPFNRVI
ISHGSGAKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGYPVEKKDISTLFRRHVEGDLEAIPWSEQGLSP
ETSTISAQLLALNAKGWWTVASQPAVNGVKSTDPIFGWGPKNGYVFQKPFVEFFIPASEF
QALKPKLQAHDQVTWFAGNAAGAFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIWKEWQRIYPPRSGSSVLLGDLSKDIWLVNVIWGDFVNGEGLWEFLGK
>A0A1F9DZ27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_19FT_COMBO_46_12|TrEMBL
MSLQENFKNKRFIVTSEIQPPIGTGVQDLIRNVERIRGRVDALTVPELKIEGLVTDTMGT
CRALRDQKFDPILQTTCREKNRIEIQEHLIRASESGVENILAFTEDYRITGDSLQEIMFF
HVDSGKLFSVIESLHQGYDISGKEIRIKPNFFVGSGVDSSWGKKVPDLELKEMEELAGLG
TQYFLTTPIFDIDSFHEFMKKVGPMRIPVVAEVILVRSAEMGLFLNKHVKPGMVPNHIIE
KLAKAPDKEKASIEIVSDLVKGLRDICQGVHFIPIGAEDRISKYLDAAKLSSL
>A0A1F9EQ51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_19FT_COMBO_46_12|TrEMBL
MSFKERLESGKFVVVTELQPPKGNNLTELFENAELLRGRVDAINIPELQNAIMRLGSLSV
CTLLKGKGMESILNLSCSDRNRLALQSELLNASALGIENILILQGDHPSIGDHFEAKPVF
DVDPIGLLGAVKRLQEGYDLMGNDLQGIPQFYVGAYVNAGAKGHILDLEIMDLEKKIRTG
ADFFFTSAVYDVSLFETFIKKVAHFKVPIIAGITLLKSVGMARYINKHVEGSSIPDSLID
KLLKAPDKQKGSVEIAGELMRALRPLAQGIQIIPIGWEKLVPGLLDQFGL
>A0A2R4TQM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas hydrophila subsp. hydrophila|TrEMBL
MGFHSARQVEALNQSLADLSGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPEMYATDLVALLKAEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDDDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQP
>A0A486XM78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rheinheimera sp. BAL341|TrEMBL
MAFANAQYLDAINRNLQDVAGKVNVSFEFFPPKTPQMEQTLWQSIERLAPLSPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASKEDLIAIAKDYWQNGIRHIVALRGD
LPPGSVAKPDLYAADLVEILRSVADFDISVAAYPEVHPEAPNAQFDLLNLKRKVDAGASR
AITQFFFDIEKFLRYRDRCAAIGIDVDIIPGILPVTNFAQLQKFASLTNVAVPQWMHKAY
DGLEHDATTRNLVAANIAMEMVKVLSREGVDHFHFYTLNRSELTYAICHLLGVRPQLVQ
>A0A0P1AW23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plasmopara halstedii|TrEMBL
MKVIDKINESIERQEVFYSFEFFPPKTLAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
RLTLELSANAQKLSGLEMLMHMTCTNMTEADIKKALNQAKDAGIQNILALRGDPVRGATS
FDECDRGFSHAIDLVRFIRKTYGDYFCIGVAGYPEGHTESTDKKTDTQYLKEKVDAGADF
VITQFFYDVQIFVKFVEECCAIGITVPIIPGIMPIQNYGGFERMTSFCNIKVPDAVRRSL
DPIKDNDEAVKNFGVQLSITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWKISTLSKRASESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSGTSTLKERRAMWGDTPATKEDIHHTFVRYVRGEISSLPWCDAALHAETSTIQQELA
SANSAGFLTINSQPRVNGVASDDPIFGWGGPGGRVYQKAYVECFVSPENMKIVIENSAKK
PSVQYHAVNLHGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWIKM
WASLYAESSQSEKLLNEIYSTYFLVSIVDNDFINGNIWELFEASVSPATLL
>A0A329VIG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus laumondii subsp. clarkei|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSINRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGD
LPENGEKPKMYGVDLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFRQLKRFAVMTNVRIPSWMTRMFD
GLDDDPESANLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A3A9JUV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas wenyumeiae|TrEMBL
MNQVVDAPAGPSQAQTTGSQDTLRRWLTGPRVAGLPQSMAMPAPALSFEFFPPRTEALEQ
QLWACIRRLEPLAPRFVSVTYGAGGTTQERTHATVARLVKETSLTPAAHLTCVGASRDEV
DEVARRYWDAGVRHIVALRGDAPTGEETYTPHPEGYAYAADLVAGLKRIGDFEISVAAYP
ETHPTATSAQHDIDNLKRKIDAGATRAITQYFFDTEVFLRFLDRALAAGITVPIVPGILP
VSNFKQVKKFSAMCGTNVPDWMGTLFDGLEDDAETRKMVAAAVAAEQVRLLQANGVDEFH
LYTLNRADLSYAIAHILGARPRKG
>A0A2K3JBJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon M8B2D|TrEMBL
MAYKSNLQRVLSEKKFAVTAEIGPPKGSDPGKIRKKAELLKGYADAFNITDNQTAVVRLS
SMGGSFILLNSGLEPIMQMSCRDRNRIALQSDVLGAVSVGVRNILFMTGDHQSFGNHPGA
KGVYDLDSIQLIKIVKDMRDLGVFQSGDKILAGIPDVFIGGTANPFADPLDFRVDRLEKK
IIAGADFIQTQSVYNLDKFKMWMDEVYSRGLDKKVFILAGVTPLKSVKMVERMKFHVPGV
DIPDEIYKRMINTPDPKSEGYNVSLELIDEIKKIKGVSGIHITALFWEDIIPKLVRESGF
YPRP
>A0A7W0P9L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAHRLVERLRNGPAIVADGGMGMLISSAVPRLRCPEEANLRAPDAVVSLHVSFIRAGADL
IETNTFGANRLKLAAHFLEDDFARINSAAVKLARDAREVCGRDVFIGGSIGPLGEIGEVT
DERRRELFAEQASILEGRGADLFMVETFYDLDELVAAIEAVQSVSSLPIVAMLTFDEDAE
TLAGVSAREAAIRLAGYDLAAIGANHGAGLLAALAALESMGHEEGGRPLAALPNIGLASL
SGGRVIYPHASPEYFEEFAAHARALGARLIGGCCGTTPVEIAAIRSAVEHERKPAAALVF
GERELVVPTLTEPTETELERLLREGEWVISVQLDPPLGGSHAGLLEVARTIKESGRAHVV
DINDNATARVGMSSMMTAAAIERIAGIETIPHLTPRDTTIMGLESLLLGAHAEGVRNILA
VTGDPPEVGDYPGSGGVYEVDSIGLTQMITRLNQGEDYNGRAIDAPTTFFVGVAVNPTAD
DLGVEVERFHQKLEAGAKFAMTQIVFDLSYLDAFVERLGGTSPIPLLVGLWHLKSHQLAL
RLHNEVPGIVVPEPVQEALRDAGPRAPEVGLQLYHELFTEARERYAGVYVVAPFRQPAAA
VDLLPARAIVPSETTGRPA
>A0A7W1ITM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVSKKRRGAADLPEDQRAALKNLVAQPKFELIPLSTALERAQALPPGCVVTVTASPSHGL
EATLDLACDLLAMGHDAIPHLSAHMVHDRAHLDDLLSRSRECGLRRAFVIGGDSKEPGQY
PDGLSLLRAIHDHGTPFPEIGVPSYPEGHPDIADDVLLGVLRQKQPLASYMTTQMSFNPG
AIVSWIGRLRGEGITLPMHLGLPGVAELGKLMTISARIGVADSARYLKKNRRMIGHLIKG
SFGPDALLERLAPTLADEAADVRALHLFTFNQVQDTVDWQRRMLEQLGGE
>A0A538J3M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPERPRRQGRSSFSLRRCSGASPAASGTLNGCSPSIAAKRASSHPSSSVDCFTSPVSRFL
DRLSSGPPIVADGGMGALISAAVPRLRCAEEANLRAPHAVVSLHVGFVNAGAELIETNSF
AANRRKLAYHFLEDELERINSESVKLARRARETAGRDVFIAGAIGPLGEAASSRVRRELF
GEQAAILEGRGADLFVIETFDDLEELVDAVEGVQAVSGLPIVAMLSFDEGAETSAGVGAR
EAAERLAGLGVAAVGANHGAGLLAALAALEQMDGDVPLAALPNIGLASMAGSRVIFPHAA
PDYFAEFAAHARDLGARLIGGCCGTTPAEISAIATALREERRPATPLDSRGLAAALGEEQ
LETGLARALREREWVVSVQLDPPLGGSSRGLVDTARELKESGLVGFVDVNDNATARAGMS
SLMVSATIEREVGIETIPHLTTRDWTVLGLESMLLGAHAAGVRNILAITGDPPEVGERSQ
AVFEIDAIGLTRLVTALNHGEDDDGRPIDAPTSFFAGVAVNPTADDLELELDRFRQKVDA
GARFAMTQIVFDLDELDRFRDALGGEWPIPVLAGIFPVTSYRLARRLHDEVPGIVVPEKL
QQALESAGSQAAEIGMAHARDLVAEAREQTDGVYIVAPYRRPLSVVELL
>A0A7V9Q173|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSDFQQVLAELLARPRYEVIPLDGIEEQVLEHVPRDVKLTVTASPTKGLDPTLDLVERLA
AAGYEVVPHLSARLVLDEGHLRWILARLHEAGIGEVFVVAGDASQPAGQFEGAAALLRAM
AEHRHEIAEVGITGYPESHPLIDDETTIQAMFEKAEFATHIVSQICFDPQVTVRWIENVW
TRGTRLPIYVGIPGPISTARLLRASSKIGIGDSARFLRKHGSLVGRLLLPGAYSPDKLLR
GLEPALVDPARRVAGFHVFTFNEVEATELWRQRRLEHLGEPVLARASGNALR
>A0A6L6A980|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAHISDLLAAGRTCSFEFFPPKTDDAARALEQTIAELAPLDPSFISVTYGAGGSTRERTR
DVVINIERNLGITAMAHLTCVGHTRAQLDSLLDEYKAAGVSNILALAGDPIVDDNGVVAE
SEFEFAMELVELIKEKGDFSIGVAAHPEGHPRSEDLYSDRRRLADKLNVADFAITQFFFE
AEPYMRLVEGLSAFGCEKPVLPGIMPVTNAAQVVRFAQLAGAEFPPHLAARFDAIAEDGD
AVRALGVELASELCQRLLDEGAPGLHFYTLNRSTATREIAANLGLGDASSAGV
>A0A7V2QHK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoflexia bacterium|TrEMBL
MAEERTNGYKSGSNLEKILRAGHFAVTAELGPPQSADPEVIRHKARLLRGVVDAVNITDN
QTAIVRMSSIASAVLAMQEGIEPIVQMTCRDRNRLAIQADLLGASALGVRNLLCLTGDHQ
SFGNHPTAKNVHDLDSIQLIRMVKEMRDEGRFQCGDEIKGVVPRFLIGAAINPFADPFEF
RPYRLAKKVAAGVDFIQTQIVLDMDRFREFMKRVVDMGLHEKVYILAGIGPLKSAGAARY
MRDKVPGMLVADEYVERMQAAVKGIPKEDKKARREAWRQEGIRIAIEQIQEIKEIEGVAG
VHIMAIEWEEAVKPIVEGAGLLPRPEV
>A0A7K1AHI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MIELSFEFFPPKDQPGEERLWQELTQLRSLSPKFVSVTYGAGGSTRERTIRVTEEIGQRT
GLDTVAHLTCVGSTQSELSEVLDSYKGAGIKEVLALRGDPVGGPLATWESTPGGFDHADQ
LVKLAVEKGLGVGVAAFPDLHPASNGNVELDLETLLRKEEFGATFAISQFFFEISSWERL
MNQLEKAGSNLKLIPGVMPVTNVKQIVKFAQLSGTQIPDKTRTRFEAVAEDEKAVRELGV
EIAAELCTQLLELGCKSLHFYTMNTAEATVKVCQSLDLGK
>A0A7K1BB29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARIADLLASGPTFSFEFFPPKNEAGWLSLGRTIAELEHLGPHYVSVTYGAGGSTRTRTA
DLVSWVKRQTPISPMAHLTCQGHTRAEIRDILIDYRAEGVQNLLALGGDPPADGSEHAVS
EYRFSSELVDDIRAFGGFSIGVAAHPEGHPRSPDLVSDRAHLARKLADADFAITQFFFEI
DHYLSMMDDLASHGVDKPVIPGIMPVTNLAQVSRMAHMSGAEVPRWLVEKVSKAGDDPEE
AVRIGVDIATELCARLLEVGAPGLHFYTLNRSGPTRDLWRQLGLDAPPDAG
>A0A7K0XUD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRLEKRMYSFEFFPPKDLAGEERLWQALSSLATLSPDFVAVTYGAGGGTRDRTIRITSEI
TARTKIPTVAHLTCVGSTRDELIDILARYKESGIKSILALRGDPVGGPRAPWTPVDGGLT
HADELISLAREHGDFTIGVAAFPDGHPNSGGDFNKDVEVLLRKESLGASFATTQFFFEVD
KWKRLVDALEKRGSTMPIFAGVLPVTNVKLLTKMAELGGTPIPESIAARFAAVEDNPDDV
RKLGVEIALNLCNELIDAGVPGIHFYTMNSSTATSEIFASLKDRR
>A0A7W0L0U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSTNLWPGDESRQLLAGLLERSAFEIFPVPGIEKRLGALSECTPITITCSPTRGIAETLT
LTEKLRSRGLQVIPHISARLVRDDAHLHRVVERLTSLEVVNLFVVGGDVKEPAGRFSSTL
SLLGALKDISHPFESIGVAGYPEGHPFLDDHSLIEELKAKEPLATYVVTQMCFDPGAIVS
WVESIRKTGIRLPVYIGLPGATHARRLLAFSMKIGVGDSARFLTKHSNLVMRLAKSRYRP
DDLIGGLAPRLGDPALRIRGFHLYTFNEVAATEEWRNQLVQDLEENQAADVQRKRDKPLD
>A0A7K1F4N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNQQNGLEPRKSLLPRPTISFEFFPPKDEQGESNLHLTIEELKRFNPDFVTLTYGAGGST
RDRTVRIAAEIIARHQISTMAHLTCVGSTRKELTEILHEYSKVGVKDLLALRGDPTGGPT
SEWISTPGGFDFADQLVDLAAKMGGFNVGVAAFPDIHPASHGNFQQDIEVLLRKEELGAT
FAITQFVFDSERYAQLLFTLRDRGSKLTLYPGIMPVTNYMQIVRMLELSGGTMPSATRLK
FARYQNDPASIKELGVEVAARICEEVFEVGAEGFHFYTLNSAVTTSQVVSRLSMLNFSS
>A0A7V4JHS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGSRLREALASGEFVVTSEVAPPKGTNLETLTHHIELLKDRVHGLNVTDHQSSVMRYPSL
GGCLLIKEHGGEPILQMTCRDRNRLALEADLLFAASRGIHNV
>A0A538I5X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSATQTRSRFLERLQHGPAIVADGGMGALLSAAVPRLRCPEEANLRAPDAVVSLHVSFIN
AGAELIETNTFGANRRKLGHHFLEDDLERINSVAVKLARDAREVTGRDVFVAGSIGPIGE
PLASRLRRDIFGEQASILEGRGADLFMLETFYDLGELVDAVESVRSTSSLPIVALLTFDE
GAETIAGTTADEAAQRLADLDVAAFGANHGAGLLAALAALEQMGKDGKPLAALPNVGLAS
LAGGRVIYPHAAPEYFAEFAAHARDLGARVIGGCCGTTPAEIAAIRSALEEHRQPAAPLQ
FDERELVVSLGEEQRETGLARALREHEWVVSVQLDPPLGGSSAGLVDVARGLAESGHVGF
VDINDNATARAGMNSLMVSATIERECGLETIPHLTTRDWSVVGMESLLLGAHAATR
>A0A6L5FWI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDGSGTHESPVPPPSFLDLDGFKILCEIEPSWKPDIAHVRKQIQVLDPVVDGFLIPDNHL
GRATMSSVAVAHEVSYMGGLSIACVNARDRNLLGFRRDLLTAAAYGVQHFLFVYGDAPKE
GRRAEDLTVRGMIEEVQSFTTGPLFHGFPNFRIGTTARVGRPLTWRAKADFLFVQITYDV
ERLLEWRRTIDFDGRVYAGVIVLASSRMAQRINATIPEIRVPQAIIDKLDDDPELGIDLA
WQQVEAIRASGAFDGVHLVPVSRYEAMAARLRSRL
>A0A6I3EVA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARIADLLAAGRTYSFEFFPPKTDGAQLSLGRAIGELEPLAPSFVSVTYGAGGSTRQRTH
AVVSWMRKETTLTPMAHLTCQGHVRAEIREILNDYAVDGVENILALGGDVPTDGESAPSD
YTFASELLEDVVADGRFSVGVAAHPELHPRSPDRATDRKFLAAKLSRADFAITQFFFDLD
VYVQMVNELADLGVTKPILPGIMPVTNKNQIRRMAELSGAAFPTWLSERLDRTDDAEEIR
RIGVDAATELCQGLLDVGAPGLHFYTMNRSTATSEIYANLGLSPTR
>A0A521XR62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MLLHPDPQVSGIKGTHRGEGTAVPVSRHRSTYPARVPSHQPPQPRVRDVIAAGGRSFSFE
FFPPKTDEGERALWQALRELEPLRPTFVSVTYGAGGSTRDRTVRVTARIAQQTTMTPVAH
LTCVGASPDELRAVVAQYADAGVRTILALRGDPPGGPGQPWVQHPGGLAHADELVRLIRS
LGDFSVGVAAFPDKHPEAVDLEADAVALARKQDAGADFAITQFFFRARDYFELVERAARH
GCDLPIIPGLMPVTNLAQISRFAAFSGAALPDELTARFAALGDDPDAVRRLGVEITTALA
DDLLAAGAPGLHLYTLNRSTATREIYAALGAAVGNR
>A0A316JGG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aquiluna sp. XM-24bin5|TrEMBL
MQISFEVYPPRKVEDTPKLHEAILRLSELSPEFISVTFGAGGSSTRDSLSVLKFIRDNSG
ASPLAHLTCVGTTEQDARSLVGEFLAEGIHDFLALRGDLPEGQTSMPPGRLSRADQLVSL
IEELRPGQLGKTAVAAFPNGHPESGQERTDIDALLAKQEAGADFAITQLFFFAQDYLRFV
DLARAKGVEIDLIPGIMPIVSPTRLSRVLELSGESEPKALAEDLRSAPDAEARRRAGIEW
AANQVRDLRDAGVESVHLYAFNEYANVTEVLRRAGVA
>A0A2J6Q600|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyaloscypha hepaticicola|TrEMBL
MEKITTKIAALPPGTPYFSLEFFPPKTPMGSSNLRARLARMSHSLRPLFVTVTWGAGGST
ADRSLELAELCQRELGLTTCLHLTCTNMKRELVDRALEDAKALGVRNILALRGDPPREDY
GYSDGGGAEEKEFEWAVDLVRYIRKGYGDYFCIGVAAYPEGHADESHPEGQSLEHDLPYL
VEKVKAGADFVMTQLFFDVEAYDKFERRLREHESGVFKDLPIIPGMMPIQSYQMIKRTTK
LSHAKMPKAVMDRLDAVKGDDEMVKKVGVDIVSELVTHIQNQPSPGPRGFHFYTLNLEKA
VSFILERTNLIPCSPTDDDCAIVEEPMSLPLQFSVQALSINGSQTNRSHHRKSRRQSSVG
ADPYNRIIVTAPKTSNPSYEATGLEAGIPAEPINTRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSVNQAIKLWGYPTSREDITDLFIRHIEGSLSAIPWSE
QGLNEESHTIKSQLLKLNKKGWWTVASQPAVNGVRSSDPVFGWGPKNGFVFQKAFVELFL
PSEDWKTLQSKLTSPSISPFVSWYASNAAGDYLSSESNTASKAEGGNGTNAVTWGAFPGK
EIITPTIIEEVSFRAWAEEAFGIWGEWGRVYGPGEKGQRSRKLIEGVKGDVWLVNVIHHG
YVEKEGLWEMLLE
>A0A0N1LAH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|beta proteobacterium AAP99|TrEMBL
MKLPAISFEFFPPKTPEGRSKLQATRQTLSAFGPEYFSVTFGAGGSTREGTLQTVQDILA
AGQVGVPHLSCVGAERASLKALLQEYQALGVKKIVALRGDLPSGYGMGGEFRYARDLVEF
IRTEFGETFEIWVAAYPEYHPQARSPADDIARFADKVKAGASGAITQYFYNTDAYFHFLE
QVSAQGVDIERTPIVPGVMPIASFTQLARFSDACGAELPRWMRVKLASYGDDVESIRAFG
TQVVADLVDQLAAVEAPALHFYTLNQPGPTAAVLDAVGYSKRS
>A0A5N1FKP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium amycolatum|TrEMBL
MPLSPGRQVTIRQALSMPSAGSIPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFASVTY
GAGGSSRDRTLRIAQRVSKQPLTTLVHLTLVEHTVDELREILRSYLSAGLTNLLVLRGDP
PGDPLGPWVETEGGLHYASELIELIKAEPEFEKFEIGIASFPEGHYRSPDLDHDTQYTLA
KLRAGAEYSITQMFFDIEHYLRLRDRLVEADPVHGAKPIIPGLMPITSLRSVRRQVELSG
AQLPSDLEERLIKAADGDEQANKDEIRKIGIEFSTNMAERLIAEGVPGLHFMTMNFARAS
QEVLHNLGMAPAWGTGQDMLRGGF
>A0A2J7Z2U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces malaysiensis|TrEMBL
MTLATDQEGAAPRTARAAVAHALRNATYEILPFKSAEEKVLAHVPTDVALTVTTTEAKGL
GPTIDLAASLSKQGYSAAPHIAARLVRDRAHLSDIVDQLRDSGIDRLFCIGGDAAEPVGD
YTDALSLLQGLRDLGHPFSSIGIGGYPEGHGSISDELIERALESKAPYADLIITQLCFDA
DTTIRWARKAQDRGITLPIRVGIPGAISRQKLIRVSAGLGLGQSARFLKKQQTMFWRFFL
PGGYSPNKLIQKLTSAFAEQDNNLRGFHVFTFNDLDSTEAWRKAWLARLT
>A0A1W9SD50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium 4572_119|TrEMBL
MKVSEHLKDQTNPGFSFEIIPPARGKSGKIIIDIVEKLKHFDPPFIDVTSHAAVASYEEV
DEGIIKRRVRRKRPGTLGICGVIQNRFGIDTVAHLLCRGFNQEETEDALIELQFLGIENV
FAIRGDDTNYKKPVDPNRHENTYTSDLVKQIANLRNGIYVEEIINADPMDFCVGVAGYPE
KHFEAPNLKIDIRNLKKKVDAGAGYIVTQMFFDNEKFFNYVKQCREMAINIPILPGIKII
HHKHQLVSIPRNFHVDLPEEFADELMSNPKHAEEIGFNWALKQSRELLEAGEKHLHFYVM
NDAESISKLLKKL
>A0A0S8B9V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium SG8_39|TrEMBL
MHEVSFEFFPPKTPAGQDKLRGTWRALAAFKPRFFSVTFGAGGSTREGTLETVLAIRAEG
HEAVPHLSCVASSREEVAAQLARYRERDIRHLVALRGDLPSGHAVAGEFRHANELVAFIR
QTTGDWFTIDVACYPEYHPQTRNAADEIRNFRKKVDAGANAAITQYFFSADAYFRFVEEC
RAAGIDIPIVAGVMPIANFSQLARFSDVCGAEIPRWIRFKLESFHDDSASIRAFGLDVVT
RLCERLLAGGAPGLHFYTLNQAPLSAEICKRLGV
>A0A2N0KWE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Casp-Chloro-G4|TrEMBL
MPQIAASSLEQGRRPLIICDFSPPRGFDTELLEPARFLDVDWISIAYNPGRSVRVNSAFA
AQWVKANTGKDVVFTLATRDMNKLAVQSLLLGAQLLGLENVVVVRGDDFTERDLAANKSV
NDFTPSQMITSIATMNEGLDFKGLKLRQPTRLCVGATIDMARGMDRELLLTNRKIRSGAQ
FLMSQPTFSSETPRIFHEQYVERFREAITIPIFHGVQVMVPEGIAFGDIPRWVTDDLAKG
RPGRDVALQILEDFASAGLNTIYLVPPILRGGGRDYETTQSVLEVVRGQ
>A0A2W4JGC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MALGLPSVLPGRRPSVGELVRRGRPTFSFEFFPPKTPEGERLLWQTIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIASETTLLPMAHLTAVNHSVAELRHMIGRFAAIGVRNVLALR
GDPPGNPMGEWVPHPEGLRYAEELVRLVKQSGDFSVGVAAFPYKHPRSPDIATDTAYFVR
KCRAGADFAITQMFFDAEDYLRLRDRVAAHGCDTPIIAGVMPVTKMATIERAEQLSGAPF
PPALAARFERVADDPEAVRQLGIEQCSDMCQRLLDEGVPGIHFITFNRSTATREVWRNLG
VGEKV
>E0Q2G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. oral taxon 071 str. 73H25AP|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVVPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQILDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A076HQN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp. APR13|TrEMBL
MKVTEHLTRANGKTLFSFEVLPPKKGENIKNLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRKRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGSFKPDPDGHAYACDLIGQVSDLNKGAYLDEKQDDTWATDFCIGTAGY
PEKHFESPNYGADLRYLKHKVDRGADYIVTQMFFDNEQFFAFEKRCREAGITVPIIPGLK
PLTTKSQLTMLPRAFYLNIPEELADAVHLAPDNAAAREIGIEWCINQSRELMAHGVPCLH
YYSMGKSESIRQVAAALF
>A0A537ZPU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDELFTTSGPVFSFEFFPPRTPEGVETLFETVEALKPLGPSFVSVTYGAGGATRDGTV
EIATRVKREHGLETMAHLSCVGETTQGLVEILDRLEAAGIDNILALRGDPPRGETEFTRP
EGGLDSAADLAGFIRQRYGFAIGGACFPEVHPEAPSLEADLAYLKTKVTSGASFLITQLF
FDNRIYFDFVDAARASGIEVPIIPGVIPIASYAQIVRFCQLCDASIPKLLAEAMDALGGD
QDAEAELGTAYAARQCEELLAGGAPGVHFYTLNRAPATRAVLAAMRVGRPWERLK
>A0A3P1WWL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachnia propionica|TrEMBL
MLSVADLLAGASSPLLSFEFFPPRSAEEQPRFDTSVERLVAFSPAFLSVTYGASGSTRDR
TVAATASLAARGQATVVGHLTCVSQTRDDLLRTLDAFAAAGVRDILAIRGDMPGGPQQPW
RQHPEGLRNATELVRLIKGHGDFCVGVAAFPNVHQPDNDPELDARIVVEKARAGAQYAIT
QLFFESHRYVELVTRVRERGCDIPIIPGIAPLTVITQIERFAALADCPLPEDLVAELRAA
KDPAEVRRIGIGRAIDLCRDLLAAGAPGLQFFTQNRWQATSEVLRALGWGQRGPDVS
>A0A354XS18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRVDNPTVSFEFFPPKTAEGEVKLFEAIHTLDVVKPDFVSVTYGAGGSTRERTIKVACDI
FAKTGYRTIAHLTCVGATRAEVRAILEQYEQAGITDILALRGDPAEGPTAPWITTPDGFT
HADELVQMAHSFGSFEIGVAAFPNMHPSATSFEQGVDVLMRKEELGATFAVTQFVFQPEA
YVRLTTELARRGSTLTIYPGIMPVTSFRQFTRMLDFANGEIPDAVMAEFQRHQHDPASMR
EIGINIATRVSEEVLDAGAEGLHFYTLNT
>A0A2I8CRZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAITLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQVKSFLTKNNYSQQILACVMPLTLGRANYMVKHKVAGIVITPHMLKVLAEEKQTGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVK
TGKEFTPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILREKLIPTVPLETRGTSSWKNWYLATEA
>C7MG28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / JCM 11609 / LMG 19847 / NBRC 14762 / NCIMB 9860 / 6-10)|TrEMBL
MSATTTLPELERTAPVRHRPALSYELFPARSDVSFERLQETIAHLEATGPDYVSVTSRAR
HGNLARVIEVTEHVLAETSLRPLVHLTSIGSTRAQLTTIIHALLDRGVRGILALRGDQPE
GHRLEDDEVPFARPLIELIRDIERERTATLAGGRVSIGVAAYPLRHPESPTTSHDTEVLV
AKEKAGADFAITQVFFEPSVYCGLLARAEEAGIRMPIVPGLVPATNPRRLERLAAISGVE
APRELLHQLEIASDEVERRRIGVRFTVDLARRVLDAGAPGLHLYTFNSHADALDVLDHLD
LDRWSATPQGDAR
>A0A8I3X2I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callithrix jacchus|TrEMBL
MVNEARGNGSLNPCLEGNASSGSESSKDSSRCSTPGLDPDRHERLREKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCHQRLEEITGHLHKAKQLGLKNILALRGDPTGDQWEEEEGGFNHAVDLVK
HIRSEFGDYFDICVAGYPKGHPDAESFEADVKHLKEKVSAGADFVITQLFFEADTFFHFV
KACTDIGITCPILPGIFPIQGYHSLRQLVKLSKLELPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCRELLASSLVPGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKNYYLFYLKSKSPREELLKM
WGEELPSEESVFEVFVHYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGVL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYE
EGSPSRAIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNEREAETL
>A0A8D6GZF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSKEKVLHFSGK
ARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKKAKSFLIKNNYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQVGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVTTGKEFTPEITRFSC
QPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAKALLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKQT
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A8J7I0P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dendronalium phyllosphericum CENA369|TrEMBL
MDNNHSHTILNSFPRAAQAGEFLVTAEVAPPKGGNPQHMLQMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQNGIEPVCQIACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHSDAKAVFDLEAVRLLQLIRKMNQGFDCNEKPLTDGALDLFVGAAVDPQCASWSGLQS
RFERKIEAGAQFFQSQLITDFERLEKFMDKIAAGYKKPILAGIFLLKSAKNAQFINRCVP
GVNIPQHIIDRLAQAKDPLEEGMKIAAEQVKIARQLCQGVHMMAVKREDLIAPILNLAGV
APVNQLVAIK
>M3F6N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira borgpetersenii str. 200701203|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTQDGDLKLMGTVKELARLDPDFVTVTYGAGGSTRDK
TAQILSEISKNYSFPTVSHFTCVGANQDQIFKTLKEIRSSGIVNLMALRGDPPKRRGKI
>A0A2P9H6T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MQSPRVFSVEFSPPRSPEGVEKLRAARMELEQVAPAFYSVTFGAGGSTREGTLSTTLEIH
AAGLHAVPHISCVASTRASVRELLRTYRAAGIRHLVALRGDAPSGMAGSAGEFRYAADLV
ELVRADFGDWFRIEVAAYPEAHPQARSPAEDVQHFVRKVRAGADSAITQYFYNDDAYRYF
VDEVARLGCTVPIVPGIMPITNFTQLARFSDNCGAEIPRWIRRRLESFGDDRASIRAFGA
DVVTALCERLLAQGAPGLHFYTMNVAAPTLEIWRRAGLPVPKQ
>A0A2D7U699|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp. MED195|TrEMBL
MIRLSSALQSSLEAGTVTITAEVMPPRGGDASHALEMARALKGLVHAVNVTDGSRAVMRM
SSLAVARLLLDEGIEPVLQMACRDRNRIAIQADLLGAHALGI
>A0A432CG46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. RSP49|TrEMBL
MKVTQHIEAAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYMD
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKLGGNDFAVDLVKQINQLNCGKYLHDLMDVDDKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVYQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A2S4YN97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ru72|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGQRNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSSEWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEVMPVTSVRMLQRLPQLSNAAL
PDGLKERILAAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQRA
>A0A521API1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solitalea koreensis|TrEMBL
MKIPEHIKNAKKPLFSFELLPPLKGQSISQIFESIDPLMEFNPPFIDVTYHREDFIYKKR
HDGLLEKVSTRKRPGTVSICAAIQFKYKVDAVPHLICGGFSKEDTENALIELKFLGIDNV
LVLRGDARKEDGGFIPEPNGHAYASELMGQVLEMNQGKYLHEELISADKTDFCIGVAGYP
EKHFEAPNLRSDLKYLKMKVDMGAEYIVTQMFYDNKKYDEFVKACRAIGINVPIIPGLKP
ITTKKQLTLLPKVFHIDIPEDLADAVEACKTDKEVREIGIEWCIQQSKELIDLGAPVLHY
YTMGKSDTTRRIASKVFTDTTHRIASQVF
>A0A3N5N8W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiaceae bacterium|TrEMBL
MDNLKERRSRLVGDGDINVSFEFFPPKTEKMEETLWGAIRRLEPLRPRFVSVTYGAGGST
RERTHATVARLARETCLVPAAHLTCVEATKEEIDAVARLYQASGIHHIVALRGDPAGGAG
SRYAPHPGGYANAADLVAGLKRIGNFEVSVAGYPERHPDSPDLAGDLDNLKAKVDAGASR
VITQFFFDNSHYLRFLEQARAAG
>A0A0D1ELY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio parahaemolyticus 901128|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDATRSELIEIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRVAVEA
>A0A0E1KZY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum CDC_1436|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIHDTLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKNIIGE
YNYAFELIEKIKANNKFGVSGACYPEGHIECESLEQDIRELKRKVDAGAEHLISQLFFDN
NVFYEFLNKAQQKNINVPIQAGIMPVVNKKQIERIVEISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A7D5ZJQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NEAU-sy36|TrEMBL
MALGTASTRTDRARTVREILAGGKKTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDTDVAHFVD
KCRAGADYAITQMFFRPESYLRLRDRVADAGCDTPVIPEVLPVTSVKMLERLPKLSNADV
PDALKERILAAKDDPAAVRSIGIDFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A3Z8LAR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSGKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEIEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A8J3YR07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Virgisporangium aliadipatigenens|TrEMBL
MPGRYPSIGDLVRESAPTFSFEFFPPRDADGERQLWSAIRDLESLKPSFVSITYGAGGST
RDNTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRIAAVNVRNVLAVRGDPPGNPT
AEWVRHPEGVLYADELVRLVKEAGDFCVGVAAFPYRHPRSPDIETDTANFVRKCRAGADF
AVTQMFFDADEYLRLRDRVAAAGGDTPILAGVMPVTTMNTIARSEQLSGAPFPRHLLAEF
ERIAEDKVAVRKLGIEHAALMCERLLAEGVPGIHFITLNRSTATREIWQHLRADSVV
>A0A1M7RNK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptosporangium aurantiacum|TrEMBL
MDRTIADRGPAARASLRRAFETLGFEVIPFKRTEEAVLAHVPKHVPLTVTASPAKGQDAS
VDLAVSLAGHGYAVAPHLSAQQVRDRAHLADVVARCRQSGITHVFVIGGDRTDTPTEFSD
ALSLLRALHELDHGFTDIGIGGHPEGHPAVSEEVLFQALAEKAPMATHITTQIVFDPRVI
LSWARELKRRGIDLPVYVGAPGAVSRQKLLRVSGGLGIGESAKFLKKQQTLFWRFFVPGG
YNPDKIVKGLAPHIGKPDNAIAGFHIFTFNDLEPTEVWRQRTLRSLA
>A0A1X2L9T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium vulneris|TrEMBL
MPADSGCPKRMEYGPCGGVRPDGQCEMLPSPCVFDDVVPWSGHRPAPRPVSAPRVLTDFS
ATPFDPDDIAATAAILASGCDAVLVGEHQNKPDFPPTLMASLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSIDVDTVLCVTGDGRGYDVRADVTQTFDLDGPRLVSLAASVGMTAAVP
ETPTAPPVHRRPARLVEKQRAGASLAVLNHVPFPDMVADFMRTARSAGLTIPVIAAVAVF
TDSISAAVLEGLPGLELDPAVTQRVLSAPDPVATGIAAAVSEARALLSIEGVEGVNVSGL
ASASGPRVGAQIKAEVGRRIRAEERRL
>A0A4S2H7W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinicauda pacifica|TrEMBL
MTQPPRDSLAPAKVSFEFFPPKNDEMEARLWDSISRLEPMDPAFVSVTYGAGGSTRDRTH
RTVRRIVTETSLKPAAHLTCVSATCEEIDDVIRDYWAAGVRHIVALRGDPPGGIGECYTP
HPGGYANGAELAAGIKKVADFEISVGCYPEKHPESATWEYDLDLLKQKIDNGATRAITQF
FFDPEVFFRYRDRARKAGIDIPIVPGIMLQPNFKGLKRMASMCGASIPQWMDELYEGLDD
DVKTREMVTANLAANLCTALQKDGVDQFHFYTLNKAAMALSTCRLLGLKPAELEDA
>A0A318H796|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium moriokaense|TrEMBL
MRFAASMIVDDLIRNANIELIPLRGADEKFAAVPTDTTITITCSPKFGLERTLEHVARAR
QMGRRVVPHLAARMVKDEEQLQNFLDALNLHGVDDLYVIGGDSERPVGKYSEALEILEAI
QYLDHSLVRIGVACYPEGHPEIPDAKLTEALQHKQQYADYMVSQLCFDSAALTTWLAATR
NAGILLPIRVGIAAPLHSRKLIELSLKIGVGSSVKFLTKQHGFIGKLLLGRAYAPEGLVT
EIVAHDRFKDLGIEGLHLFSFNQVQATLEWQNRISDGGGTK
>A0A4Y6QXI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. NIBRBAC000502772|TrEMBL
MSKEAVARVRLEVVPSADLLTQLAAALDTTGSVSVTCLPHHGPARTVEASVHLARLGYHT
VPHLAARSITGEAELHSLLLQLQEAGVSELFLVAGDRRTPAGPYSWSGELLEAVNAYSPD
FSIGIAGYPEGHPQLSQEQLSSSLLTKAPLASSMVTQMCFSAEAISRYVRSIRTSGIQLP
VWVGVPGPVSVRKLVSLGARLGVGRSLKLARGTGMAGALWRRDDFLSYDSGRLIREVHQE
LAGDPLFAGFHVYTFNDLGRLPGLLDDLRALQPTISLAPGSTSIPLFPAKI
>A0A2K9EKW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetivibrio saccincola|TrEMBL
MKICELFRMKKVFSFEVFPPRRIDSVSIIYDTIEKLKGLNPDFISVTYSAGGSESNTDTF
KIASAIKNNYGIESVAHLPSINHTKGEVLKMLEDLRTAGIENILALRGDVNPSFSPKNDF
KFASDLISFIKEHGDFNIIAACYPEGHFESPSIIDDIRNLKRKVDAGANQLITQLFFDNN
YFYSFMERAAIAGINIPIEAGIMPVVNKKQIERIVALCRVNLPKKFLAIMNRYENNPEAL
RDAGIAYAVDQIIDLIAQGVDGIHLYTMNNPYIAHRIYEAINTLLVA
>A0A1H8WJ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium URHD0017|TrEMBL
MSPDTGPLGGPYSVSTAEFPARAPQRLKVSFEFSPPKTEAAERTLWETVTRLTPLQPTFF
SVTYGAGGSTRQRTHETVARLKKETGVDAAAHLTCVGATQGEIDEVARAYWDAGIRHIVA
LRGDPPGGMGGKYSPHPGGYANAAELITGLKKIGPFQISAACYPEKHPDSADAKADLENL
KRKVDAGADRCITQFFFDADDFLRFRDSAAAGGVNAPIVPGIMPVSNFQGITKMAGLCGA
KVPAWLASLFDGLDDDIETRRMIAATVAGDLCRRLRDEGVDQFHFYTLNRADLTFAICHL
LGVRPQ
>A0A2Z3GQC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter nivis|TrEMBL
MKVTDHLAQADGKTLFSFEVLPPKKGEDIHTLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFTKEETENALIDLHFLGIDS
VLALRGDPIKSDGVFKPEPDGHAYACDLIGQLADLNKGEYLDEAQDDTWATDFCIGTAGY
PEKHFEAPNSGADIRYLKHKVDRGADYIVTQMFFDNEQFFDYERRCREAGITVPIIPGLK
PLTTKAQLTMLPRTFFLNLPEALVEAVSQCRDNEAARAVGIEWCLNQSRELMAHGVPCLH
YYSMGKAESIRKVAKELF
>A0A862ZP49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O145|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPLGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7G6A4Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. Se16.2.3|TrEMBL
MDTHNFSIEFFPPKTPEGADKLRATRRQLAELNPKYFSVTFGAGGSTQQGTLDTVLDIMA
DGHLAAPHLSCIGATRDSIRTILKQFQDKGIRRLVALRGDLPSGYGGAGELRYANELVEF
IRGETGDWFHIEVAAYPEMHPQARSPQDDLQNFARKIGAGANGAITQYFYNADAYFQFVD
NARKLGIDVPVVAGIMPITNYMQLSRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTNLCERLMAGGAPGLHFYSMNQAAATTAIWQRLASR
>A0A0K6H817|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gulbenkiania indica|TrEMBL
MSDKRTFSFEFFPPKTAEGIAKLRTTRQQLAQFRPQFFSVTFGAGGTTRDGTLSTVLEIR
AEGHAAAPHLSCIGSTRENIRAILEEYRSHGIRHIVALRGDIPSGMVEAGEFRYANELVA
FIRAEHGDHFHIEVAAYPEFHPQARSAEDDLNNFVRKVQAGADSAITQYFFNADAYFRFV
DEVQARGVDIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRQRMQAYMDDTASIRALGLD
VVTELCDRLLAGGAPGLHFYTLNSAGLVSTVWQRLGL
>A0A2A8D4Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia dentocariosa|TrEMBL
MTTVHPALSYELYPPRSHASCDSLLKTITELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLALRGDIPPENTRPLDLPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAARLAGVEMPIIPGIMPVTSLARLTKLCELAGLEVPRELAHRLETASDS
RELHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>A0A2S9AFW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. MYb72|TrEMBL
MSSETPNPRVPFSFELYPPRSASSHEALHETVRRLAAAGPDFISVTYGAGGSTGGRSLEV
LRFIREHTAVEPLAHLTCVGNTYAGAATLIREFLDAGILSFLALRGDPPVGQDEPFLGDL
ESAAQLVQLIDRVQAERAPYEESPVPGIPGAARVSARRKASIAVAAFPNGHPRSVHRWQD
VDALLAKQAAGATSAITQLFFHADDYLTFVERARAAGVTIPILPGIMPIVSPVRLARVLE
LTGETLPSELAIALDVEPTPEGRHEIGVEWAARLAREVVAGGAPGVHLYAFNQHDTVLTV
LEEAGVLPVSRLR
>A0A2R8B390|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Defluviimonas aquaemixtae|TrEMBL
MPAPRISFEFFPPHTLDASFRLWETVQTLAPLKPDYVSVTYGAGGATRDLTHDAVTTIGQ
HYGLNVAAHLTCVEATREETLAIADSYAEAGVRQIVALRGDAPKGEVSFTPHPDGFANSI
ELVDALAATGNFDITVGAYPEPHPESADTQADVDWLKRKIDAGASKAVTQFFFEAETFLR
FRDECDKAGITAPIVPGILPIISWEGAKRFAARCNAKVPPNLEQAFLRANRDGREELLAL
TQCTVLCDRLITEGVEELHFYTLNRPHMTRDVCFALGINPEVSLQNVA
>A0A4Y8KA59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Hh7|TrEMBL
MTGKDVPALEEAQAGIPAGTRINVTYLGNEDLDMRVNAARAVRLANFKPVPHISARRLTS
KAQLEEFLSRLQEAEVSSSVFVVGGDPHTPEGPYSDSAEVIRTGILQEYGVTGVSISGYP
EGHPDIKTDVLWGALQEKADSIREQGLEGTILTQFGFDTEPVIEWIQAVRERGIDFPIRV
GVPGPAGVKRLLGYARRFGVASSAGIVQKYGFSLANLLGTAGPDRFVADLADRLDGAGLG
TVKLHFYTFGGMRATANWATEFVAKQNAAAS
>A0A445N0R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MSDFKSESNLEKVLKAGHFAFTGECGPPKGANVEHLKEKISFLKGNVDAVNITDNQTAVV
RMSSCAASAILIKEGVEPNFQMVCRDRNRLAIMSDILGAYSLGIRNMLCLSGDHQRFGNH
PEAKNVYDIDSMQLIALVKKMRDEGKFMNGEDIDVPPRLFIGAASNPFAEPFEFRVHRLA
KKINAGADFIQTQCIYNMDKFREFMKRAVDMGLTERCYILAGVTPMKSVGMARYMADSVP
GMDVPDQLINRLKGAAKGKVAEEGVKFALEQIAEFREMKGVAGVHLMAIEWEHKVPEIAE
RAGMLPRPKV
>A0A1I3H2M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. OK403|TrEMBL
MNAFRPSRHGSRRPKVSFEFFPPKTAEMETALWESVRRLEPLVPSFVSVTYGAGGSTRER
THATVKRMVEETALKPAAHLTCVSATCDEVDDVIRSYWEAGVRHIVALRGDPAGGLGTAY
EPHPQGYHQTSDLVAGIRRVGDFEVTVSAYPEKHPEAASLDADIEALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRARGIDIPILPGIVPVQNFKQTANFARKTGASVPQWLADRFEGL
EEDAATRRLVAAAVCAEQVLDLIDRGVSDLHFYTMNKADLVYAICHLVGLKPEKTAAQAV
AAE
>A0A0D7K9U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax temperans|TrEMBL
MNAAKTEATGFPVSLEFFPPKTEEGAAKLRTVRQQLYALHPEFCSVTYGAGGSTQEGTFT
TVKEILSEGVSAASHFSCIGATRQSVREQLAVLKGMGVRRLVALRGDLPSGYGAGGEFQY
ASDLVAFIREETGRDFHIEVAAYPEVHPQARSPEADLKAYVAKVRAGADAAITQYFYNSD
AYFRFVEDTYKLGADIPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLEL
>R7H0P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:403|TrEMBL
MKIQDYLQTHNLLVDGAFGTYYAEKYRTQNIPELENIGHPEQIQAVHADYLAAGATMIRT
NTFIANTVALQKDWDTVAAQIQAAIQCAKLAVESYQNSESPRFIAGDIGPIPTASSLNPE
EAEAEYLKIAKLFLENGISILNFETFPDMEQLASILPKIKADFDCFLIVSFTVNQFGYSA
SGLSAKRLLQDAQQNTCIDAVGLNCGVGPRHMYQILERLELPRHLHFMALPNAGYPTVAR
NRLQFNHTASYFAEHTKKILSLGVDMIGGCCGTNPTCIQRVAETGMLSHKKPLPSSEQTA
EQAPKRVPCGFLYDENGMRKKKKIIAVELVPPFNADDEKLLESAHYLKLQNVDVLTFPDS
PSGRTRVDSVLMAEKVRRATGLEVMPHICCRDKNALAMRSILMGAQINDIQNMLIITGDP
IPSMARQTIKAVFHFDSVGLMNIIKEMNEETFAQRPLLYGGAINQSRKNLDSILRRVKKK
QEAGASFFLSQPVFTKEDADRLRFIQSETGATILCGIMPLVSRKNALFMKNEIAGVNVSD
AIIERYPEQATREEGEAVGIALAKEIIAMVDDFADGYYFSFPFNRVYLLPKILSKDPQTG
TE
>A0A6P4A196|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ziziphus jujuba|TrEMBL
MKVIEKIQDASLDEKKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPTFCDITWGAGGST
ADLTLDIANRMQNIICVESMMHLTCTNMPVEKIDHALDTIKSNGLQNVLALRGDPPHGQD
KFVQTEGGFACALDLVKHIRGKYGDYFGITVAGYPEAHPDVIGSNGVASLEGYQSDLAYL
KRKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIRTLHLYTLNMEKSALAILMN
LGLIEESKIQRPLPWRRPTNVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPHGRWGDSRN
PSYGALSDYQFMRPRARGKKLIEEWVTPLTNIDDVYEKFKKFCLGKLRSSPWSELDGLQP
ETRIINDQLGRINTKGFLTINSQPAVNGERSDSPVVGWGGPGGYVYQKAYLEFFCSREKL
DALVDKCRALPSLTYVAVNKEGSWLSNIGQSQVNAVTWGVFPAREIIQPTVVDPASFMVW
KDEAFEIWSRGWARHYPEGDASRKLLQEIENAYFLVSLVDNDYINGDLFAVFADF
>A0A1N7N792|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter aestuarii|TrEMBL
MPTPKVSFEFFPPQTLDASFRLWETVQVLAPLNPTFASVTYGAGGTTRKLTHDAVETIHE
HYGLNVAAHLTCVDATKAETQEIIDSYAEVGVTEIVALRGDPPKGADRFTPHPEGFASSV
ELIEWLAKDGRFNIRCGAYPEPHPEATDPMADVRWLKRKIDAGATSAITQFFFEAETFFR
FRDACVKEGITAPIIPGILPIQSWKGAKGFAKRCGTSIPAWVEEAFETATRDGREQLLAT
ALCTELCDNLVAGGVDELHFYTLNRPEMTREVCHALRINPGVVLENVA
>A0A0D2B1A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala oligosperma|TrEMBL
MPRKSASTSTIMDDRLPSIWSNLDPSSRYFSLEFFPPKTSSGFSNLQARLVRMAQGLRPL
FVTVTWGAGGSTATKSLELAEICQRQLGLTTVLHLTCTNMRRSAVDEALEGAKEVGIRNI
LALRGDPPREEYKDTDETGSGGQGTDSNQDFVWAVDLVRYIRRQYGDYFSIGVAGYPEGH
ADENNPEVGKQNVEHDMPYLAGKTAAGADFIMTQLTYDIQAYQAYEKRLREYVDEKGERL
FEKIPIIPGLMPIQSYQIIKRITKLSHAKIPGNILERIEAVKSDDEAVKRVGVDILSELV
EQMTELPQPEGVPRGFHFYTLNLEKSVAFILERTGLIPPVIEQASPAYSSDSDAIIDDEK
RPGYSGNQRPDGVTGGEYSHTPRHTKRRTSSVNAQPHNRVILDGTSKAPHGSKDAAQLGR
LTAPMISRHEASDKGTGIPASEPTRKHNLMISEGQGSLGREATWDDFPNGRWGPSDSPAF
GEIDGYGPSLKVGPITARKLWGHPKSHKDITELFRRHVVGELEAVPWSDEMDIDGASNGG
SGPLRAETQVIRKELLGLIETKGYWTLASQPAVDGARSDDEIVGWGPPGEGWVFQKAFVE
FFCPRQEWEDHLKPLLMEYDAGTLGWMKTDASGVFESSADSAQQDVAEKSTSKHTPGTSG
VSAVTWGVFRNREIVTPTIIENESFRAWGEEAYSIWSVWRRCFPRGSDEEKFLDKMRQEL
VLVNIVGNNYAEGHAGRGGELWKILLDKK
>A0A2D6SJI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MSASLKQVSSLLNGFSTEVTPXSASKIDNFQDHLSLGTSINVTFLAGSNLRDTVQVCKRL
NEEGFNPVPHIVARNFENTMALEIFLDLLVSTADVHEVLVIAGGIGRPLGPFSDSLQILN
SGLLEKYQIRKVGVAGHPEGSPDISKDKLANAIRDKNNWAKNSDMEAYITTQFCFEVPSI
MTWEKNIRRDGNKLPIHIGIPGPANLNTLIKFATMSGIGPSIRVLTRQTKNLTKLVFTQD
PLRIIEGIAFAKLQDPDCLVEQLHFYPFGGLAKTAAWIKDILEKSEFKNLEVG
>A0A078QUF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus str. 3775 SL|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A1W9ZPT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium arosiense ATCC BAA-1401 = DSM 45069|TrEMBL
MPADSDCPKRMEFGPCGGVRPDGQCEMRPGPCAFGDVVPWSGHRPSPRPARAPRVLTDFS
ATPFDPDSIAATATALAPGCDAVLVGEHQNKPDFPPTLMASLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSIDVETVLCVTGDGRGYDVRPDVTQSFDLDGPRLVSLAASVGMVAAVT
ETPTAPPVHRRPARLVEKQRAGASLAVLNHVPFPDMVADFMKTAHSAGLTIPVIAAVAVF
TDSVSASVLEGLPGLELDPAVTQRVLSAPDPVDAGIAAAVDEARSLLSIEGVEGVNVSGL
ASASGPRFGAEIKAEVGRRIRAEVPL
>A0A1Y3VLQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. An66|TrEMBL
MNVVDIIHEAIASKRTRFAFELLPPLKGDGSQKIFAAIEPLMPYDPAYINITFHREGIKE
TVREDGSVDWHVVRRRPGTVGISAAIQQRYGVEVVPHLICGGLSKYDIEDTLIDMDFLGL
HNVLALRGDKSQNERRFMPHPQGHAHAVDLVRQIDGMNHGRFIDGEVEECHHSKFSIGVA
GYPEVHFEARDITSDIAHLKAKIDAGAEYVITQMFFDNRKYFDFVRRCREAGITVPIIPG
LKPLSTLRHLEVLPETFSVEIPEELVREAKAHPESVKQIGTEWTIAQSRELMAAGVPVLH
YYTMSRTTNIQKIVSTLF
>A0A367VML1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira profundimaris|TrEMBL
MMTVQEIKAVRKNLKVSFEFFPPKTEKMEETMWRSIRRLAPLNPSFVSVTYGAGGTTRGR
THGSVTRIQGETGIPAAAHLTCVGHTKEEIDQIARSYWNEGIRSIVALRGDLPDAGDTYE
PTPGGYAYAVDLVAGLKEIADFDISVSAYPETHPDAPSADFEIEYLKRKIDAGANRAITQ
FFFDNETYLRFRDKCVAAGIDAPIVPGILPVTNFGSLLKFADMCGASVPQRLHWRFEGLD
EDPDTRRMVAFHEAISQVEGLISEGVTDFHFYTLNRAELTYAICHALGIRGPEQAAA
>A0A517VND1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia algae|TrEMBL
MQISELYRDGTFGLSVEIFPPRNESGDAELFKTLEELIRYQPAFVSCTYGAGGSTSKRTI
ELCALIQNQLHNTATAHFTCVNSTREELVEWLQNAFDAGITNIMALRGDPPAGQETFVPA
DGGLKYANELVTLIREHFPKMGIGVAGYPECHPEASDANVDLTNLKRKVDAGADAIYTQL
FFNNEHFYQFRERCSQAGIDRPIIPGIMPITEYRRIQRIMSMCSSEFPADLVGQLEAAQD
DLEAQFEIGVEYAIRQCEQLIKEGVPGIHFYVLNRSQACKRIFDALGFPETQENIAT
>A0A5P2ZQJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTVPEISFEFFPPRDLEASFRLWDTVQVLAPLGPRFVSVTYGAGGTTRDLTRDAVATLHK
HSGLKVAAHLTCVDATREETLAIAQDFADAGVRDIVALRGDPPKGADRFVAHPDGFADSC
ELISALAAAGPFNIRVGAYPEAHPEAASAQADIDWLKRKIDAGASEALTQFFFEAETFFR
FRDACVKAGIDAPIVPGILPIENWKGASRFAKRCGTAVPQWLDEAFATAERDGRQDLLAT
TVCTELCTDLIEGGVDKLHFYTLNRPELTRDVCHALGVTPKAHLENVA
>A0A411X503|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia albidiflava|TrEMBL
MADHNFSIEFFPPKTAEGAEKLRATRAKLSELHPKYFSVTFGAGGTTQRGTLETVLDIMG
AGEQAAPHLSCVGGTRESIRAILNEYKSHGIKRVVALRGDLPSGYGAAGEFRYANELVEF
IRAETGDWFHIEVAAYPEVHPQAKSPQSDLDAFVRKVDAGADAAITQYFYNADAYFQFVD
AAHKAGVTVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTSLCERLLAGGAPGLHFYSMNQAAATTALWQRLVK
>A0A1V5UGR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium ADurb.Bin243|TrEMBL
MSLEKPEFKQVLNEDKIVIFDGAMGTMLYSKGIYINRCFDEMNLSAPNVISDIHAEYVKA
GSQVIETNTFGANRCKLAPHGFAEKLEAINYQGAKLAVQIAKSAPHTVYVAGSIGPLGIK
IEPWGKTSVDEACEFFKEQAEALLAGGVDLFVLETFSDINEMHQAIRAVRSICQLPILAQ
IKIGNDGNATYGTTPEVFTQNLDSWGADVIGLNCGVGPKIMLDTIELMAEFTKKKLMVRP
TAGLPTSVEGRTMYLSSPEYFAEYTKRFIQHGVKIIGGCCGTTPAHIKAMAAAARVFSTD
ERKISVMVKESPQKPAPQAQPIEKEKKSRFAASICSNKFVVTVEISPPKGCDATRALEAA
KFAKDNNIDAINIPDGPRATARMSPQALAGIFERGVGIETILHYCCRDRNLLGMQSDLLG
AYASGLKNVLLITGDPPKLGDYPDATAVFDVDSIGLTNMVHRLNSGSDLGGNPIGKPTGF
FIGVGANPGAIDLNLEIKRFEYKVEAGAEFAITQPVFDIALLENFLKRIDHVRIPVIAGI
WPLASLKNAEFMNNEVPGMSIPEHLMKRMRSCDTAEKQREEGIKIAREALGAIKGMVQGV
QISAPFGRVATVLEVINGIAG
>D6LF06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium periodonticum 1_1_41FAA|TrEMBL
MKIADIYKGKSLTTSFEVFPPNDKVGLDQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIADRIKNQNGVESVAHLTCIGAKKEEIDRVLEDLEKHNIENILALRGDYPVGRELEVGD
FSYARDLINYIHEKKSDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A7S4UU22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Guillardia theta|TrEMBL
AGQGIAMAPVDASSAGKGRQGCVSDKIRHHIENGCKFYSLEFFPPNTLEGARSLIARVDR
LAKLQPKPLFVDVTWNMESGKRAIETLVAAKAVCSLDVQMHMSCTGITKKMADDLLVEAM
DADIRSILVLRGDPAPGKSDWEPVADGFKNASELVSYIRHKYGDFFSLSVAGHPGKHPAS
SSKEEDLEHLKQKVGCGADFIITQMTFKASEYQEFVGSCRRVGIDCPIIPGVLMIPPSLE
KLRAVCNHCSVEVPEDLVELLEVSKSDGAELSHCSSCCCRSLVCPALTCLSLHAPADLRE
RQGESERGREGLHAEGLLRDALLRRSWSVHVHPESREVSSGDCHKPQPQGPRRRHVRLCR
SAPAVPKAKGEGDCSTHLLGLQRHQLSHSHSQLVC
>A0A552HV66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis viridis Mv_BB_P_19951000_S68D|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSRSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>A0A249KNR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Planktophila versatilis|TrEMBL
MRSGVTYSFEFFPPKDVEGEARLWSAMSQLESISPDFISVTYGAGGSTRDRTIRITSEIT
ARTHIPTVAHLTCVGSTRDELGEILGKYRDAGITSILALRGDPTGGPRAPWVPTQGGLNH
ADELVTMAAEFGGFKIGVAAFPDGHPSSLGDIDKDIDVLLEKQRRGATFATTQFFFEVDK
WKALVDKLAAKGSSLPIIAGILPVTNVKQLNRMAELGGTPIPSSIAERFAAVEDNPEDVS
KLGVEIATNLCHQLLESGAPGLHFYTMNSSTATREIYAQIKDER
>A0A514VBG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leclercia adecarboxylata|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMAKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0Q4NMA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. Leaf61|TrEMBL
MANHNFSIEFFPPKTAEGADKLRATRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILA
AGEDAAPHLSCVGGSRESIRAILAEFKSHNIRRIVALRGDLPSGYGGAGEFRYANELVEF
IRQETGDWFRIEVAAYPEVHPQAKSPQDDLLAFERKIKAGANAAITQYFYNADAYFQFVE
QTRKLGIDVPIVPGIMPILNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTQLGERLLAGGAPGLHFYSMNQAAPTTALWQRLV
>A0A5C7R0V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolumonas sp|TrEMBL
MSFDSARQVEALNQNLAELGGDINVSFEFFPPTTESMEQTLWNSIERLSKLQPKFVSVTY
GANSGTRDRTHSIIKDIKERTGLVAAPHLTCVDATPDELRAIAKDYWDNGIRNIVALRGD
LPAGADKPAMYADGLVSLLKSVADFDISVAAYPEVHPEAKSAQADLLHLKRKIDNGANRA
ITQFFFDVESYLRFRDRCAAIGIEAEIVPGILPVSNYKNLLKFAGFTNVKIPQWLHQRFE
GIADDDQTTRNLVGASIAIDMARVLSREGVKDFHFYTLNRSELTYAICHTLGVRPKV
>A0A2D6H304|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomonas sp|TrEMBL
MTLSLKQLAEAREALGAPLFAGLAGDVEVSFEFFPPKTEKMEATLWDTLTTLAPLGPKFV
SVTYGAGGSTRERTHATVARIASETAIPAAAHLTCVDASRDEIDSIAQSYWDAGVRHIVA
LRGDPPRMGEKFVAHPQGYANAAELVKGLKQVAPFEISVAAYPETHPDADCADSDIDNLK
RKLDAGADQAITQFFFSPEAFFRFRDAYTRAGITAPILPGILPVSNVATTRKIAGACGTE
IPQWMNDLFEGLDDHPTTRQLVAATVAAEMCRRLYSGGVRHFHFYTLNRAELSFAICHLL
GLRAPKVAAAPVLQENAA
>A0A1W9MW05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium IS3|TrEMBL
MELKAGSNLEKVLRAGHFAFTGELGPPRGANAEEVRKKAAFLKGNVDAVNITDNQTAMVR
MASWAASLLLIQEGLEPNFQMVCRDRNRLAMQADILGAYAHGIRNMLCLSGDHQQFGDHP
QAMGVFDIDSMQLIQMVKKMRDEKKFLSGADLDEAPKIFIGAAANPFAEPFEWRVHRLAK
KINAGVDFIQTQCIYNMDKFREWIRRSNDMGLTEKAYILAGVTPLKSVGMAKYMQGKVPG
MDVPDAVIKRLQGVDKKKVAEEGIKFACEQIEEFKGMKGVAGVHLMAIEWEHKVPEIAEQ
AKVLPRPKVD
>A0A0G2HX05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emmonsia crescens UAMH 3008|TrEMBL
MEKISDKIAALPRDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLIDDALSEAKVLGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTYAVDLVKYIRRTHGDHFCIGVAAYPEGHSDESYPEVQDPARDLPYL
VEKTKAGADFIMTQLTYDLEAYKRFEEMLRNHESGVFKTIPIITGLMPIQSYHILTRTTK
LSHARVPPDIMTRVEKVKSDDEAVKRIGVDILCEIVNGIKKLPCPGPRGLHFYTLNLEKA
VAFTVEKCNLIPTSSEPSSDSDTDLDSAVVIAQGKQNDVPLISKRRASSMNSQPHNRLIV
DRPSDAGGSSQASTTHETQALGAGMPALNPPHRTTTLQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVNATVARRLWGYPTMKQDINNIFQRHMSGELHIVPWSEGGT
QDTGGLNPETATIRDELLQLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAF
VEFFCPSHDFETILKPIFESHGHDELAWFAMNATGDFQSSSGSTDSTADDYSGPVDVFLD
SNATGSSTGVNAVTWGVFKGKEIITPTIIEEVSFRAWGDEAFRIWDEWRRIFPRGSPTER
LLDQLKNDVWLVCAVGQKYGAGCESKEAADAEGKLLWKLLGGKDTEADSANTH
>A0A6I5X4C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetrasphaera sp. HKS02|TrEMBL
MALGQPSRLARPERLTRSIPGMLSAPSPSISFEFFPPKDDASEALLWDAIRRLESVRPDF
VSVTYGAGGTSQDRTVRVTERIARETTLTPLAHLTCVNASVAALRQVVGLYAASGVRNIL
ALRGDPPGDVGGAWVAHPEGLNHAEDLVRLVRGLGEFTVGVAAFPDVHPESAGFEDDVEV
LVRKADAGASFAITQMVFDAETYLRLRDAVAARRDLPITPGLMPVTNVKQIARMSQLMGT
PLPDAVLRRLEAVAEDPAATREVGVQIATELAERMLGEGAPGLHFITMNRSTATLEVYRN
LSL
>E6VUT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio aespoeensis (strain ATCC 700646 / DSM 10631 / Aspo-2)|TrEMBL
MHVCDLIEKNTPFISLEFFPPKEKDAWPGFFDVVEKLKDLGPLFASVTYGAGGGTQDNTL
EIATRMKRDHGIEPIVHLTSVGASAAKLDTFLAGLSAAGLENVLALRGDPPKGQEDFSFD
SQEFKHATDVIEFISRRYPNICVGGAAYPESHPESPSIQSDLDMVNLKVRMGAKFLVTQL
FFDNRLYFDYVARLRAMGADVPVVPGVLPIMNLRSAKFILGLCGAAIPGKYLSALEKANE
EGGDEAVYALGIRYAIRQAQELIDGGAPGVHLYTLNRAEACLEIGKNLKI
>A0A844ALH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tritonibacter aquimaris|TrEMBL
MSTPEISFEFFPPKSLEASFRLWDTVQVLAPMAPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLNVAAHLTCVNASRAETLEIADQFAEAGVKELVALRGDPPKGDGSFTPHADGFANSV
ELIEALSATGKFNIRVGAYPDPHPEAPNAQADVDWLKRKIDAGANEALTQFFFEAETFFR
FRDACQKAGIDGDLITPGILPIENWKGARSFAKRCGTHIPTWVDDAFEKAARDGREDLLA
TAICSELCTDLLEGGVKRLHFYTLNRPELTRDVCHALGVQPKTILENVA
>A0A6P0YJ64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO1H6|TrEMBL
MNRFRNAVKSGEFLVTAEVAPPKGADPAHMIEMASTLKGRVHAVNVTDGSRAVLRMSSLA
ASIILKNNGIDPICQVACRDRNRIGLQADLMGASALGLHNILALTGDPVKAGDHKDARSV
FDMESVRLLQMIAKLNQGIDWNEKTLPDGATDLFVGAAVDPQSPSWSGLKKRFERKLLAG
CQFFQSQLISDFDKLEKFMNQIAVESNKPILAGIFLLKSAKNAAFINKYVPGVDIPEHII
NRLAKAEKPLEEGIKIAAEQVQIASKICHGVHLMAIKREDLIPRILDMAEISPIEQ
>A0A2A6PB97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. BJ1|TrEMBL
MSPDINPLDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYSPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRRPWKHEATPAETLVAERLEHLREGIEENQQQMAEAAAH
HPH
>A0A5C7ZIM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dokdonella sp|TrEMBL
MPPISFEFFPPKTDEQRASLESALPRLKAYTPEYVSCTFGAGGSTLSYTPDTVRRLREVH
GLDAAPHLSCMGGTRDEIRGLLSDYRSMGCKRIVALRGDLPSGMASHGDFRYASDLVEFI
RAETGDHFHIEVACYPEVHPQSNDALSDLDNFKRKIDAGANGAITQYFYNADGYFRFVEA
ARALGVSAPITPGIMPISNFSQLRRFSDMCGAEIPRWLGKRLSAMGDDVESIRAFSADVV
AELCRKLISGGAPGLHFYTLNRAKPTSAVLERI
>A0A1Z5IFU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schleiferilactobacillus silagei JCM 19001|TrEMBL
MKVVNCFNERPVISFEIFPPRPNASEKAIERFYNNLDVLAGLKPAYISVTYGAGGSDNNS
GTLDLCCYIKKHYGIEVVPHIPGINFTKSAVKAYLEKLKTNHIENILALRGDLPKDGNIK
GDFQYASDLVSEIKRDGDFNILGACYPDTHPEAKDSVEDIKNLKCKVDAGVSQLITQLFF
ENDHYYQFLERCELANIDVPVQAGIMPVVNERQIKRMATMNGIRLPQKFLRMMAHYQDNP
VAMRDAGAAYAIDQIVDLLSEGVDGVHLYTMDNPVVTERICGAIKTLI
>A0A2M7NT10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG_4_10_14_3_um_filter_49_12_50_7|TrEMBL
MRIAEKLEASERGVSFECFPPKTEKGRSNLYGALGALEKYKPLFVSVTYGAGGGNRDTAV
DTVLSLKKDFTFEVMPHLTCIGAPASEIDGVLDTYKDAGIENILAL
>A0A1F9I4A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFCSPLOWO2_02_FULL_57_26|TrEMBL
MKLCEIYSRPGPVFSFEFFPPKTAKGDEGLSDEIAVLKTLHPAFCSVTYGAAGSTRAKTV
ELVDRIHRECGLEVMCHLTVVGQSKDEIRSVLKRLMELGIDNIIALGGDPPQGVVDWEPH
PDGFHHSIELVREAVACRWFSIAVAGFPEVHPRAESRDFDLRYLKAKVDAGADVVITQLF
FDNEDYYRYVDDVRKLGVSVPIVPGILPVLSVPQARRFTVLCGSRIPPRLEQVLSRVEDD
DEGAVRLGIDYATEQCEGLLRFGVPGIHFYCLNKSRSVKAIFANLGL
>A0A5P3KV12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. pruni|TrEMBL
MDPDTPSLASTITEAYSLEVSAKHIAGLAAAAPRIMRGATIAIPYLPNQDDDARLAAARM
VRTLGFQPMPHLSARRIASREQLHAFVSRAVDDAGVERCLVIAGDPPAPLGPFPDSLSLL
DTGVFERSGIRTIAVAGHPEGHPSMPAADRWEVLQRKCRSIAERGMAPLIVTQFAFDADI
VLRWLQALRAHGIAYPVRVGVPGPAGVAVLARYAASCGVSACASMLSKYGISLGKLLGTA
GPDRFVERLATGLTDAHGEVRMHFYPFGGIAQTVAWVEQYRSRSAHV
>A0A220UD32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium avium|TrEMBL
MTATTTLPELERTAPVRHRPALSYELFPARSDHSFERLRETVVQLEATAPDYVSVTSRAG
HGNLGRVLELTEHVLAETNLRPLVHLTSIGSTRDQLATIIHALLDRGVRGILALRGDQPA
GHRLEDDEIPFARPLIELIRESERERTAGLAGGRVSIGVAAYPHRHPESPTTSHDTEVLV
AKERAGADFAITQVFFDAATYCGLLERSRAAGIRMPLVPGFVPATNPRRLERLAVLSGVE
PPRDLLHQLELAASDAERRRIGVRFTVDLATRVLDAGAPGLHLFTFNQHTDALDVLDHLD
LDRWSAPSLGDTR
>A0A4R4KQX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. KC721|TrEMBL
MALGLPSVLPNPQPAIGELIRRDAPTFSFEFFPPKTPKGEQLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGAGVRNVLAVR
GDPPGDPGGEWVRHPEGVLYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDIASDVAHFVR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQMATIERSVQLSGAPF
PPALAERFARVAHDPEAVRRLGVEQASEMCARLLDEGVPGIHFITLNRSTATREVWRSLQ
AGARV
>A0A2N3GF83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium HGW-Actinobacteria-2|TrEMBL
MSFEFFPPKDDAGTAQLLTAIEALQPLRPDFVSVTYGATGSSRERTIDATQLIAARTDAL
TMGHLTCVSQSVNELRGAVDAYAEAGVRHILALRGDPPGGPTAAWERHPDGLDNATELVE
LVKASGDFCVGVAAFPDAHPEHHDFDLDARILAAKEQAGAEFAITQLFFDADAYFRLVER
VRALGCELPIIAGIMPVTNISQIERFASFSGAELPAPVVSRLRAVADDPAAVREVGVEIA
VELCDRLLAGGAPGLQFFTQNRSKATAEILRRLREIQPHH
>A0A139GV13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudocercospora musae|TrEMBL
MHISEKLAAAHAKGQHTCSFEYFPPKTAQGVQNLYDRMDMMHALGPAFIDITWGAGGRHS
SLTCEMVKVAQSAYGLETCMHLTCTDMERSKIDHALEEAYKAGCTNILALRGDPPREQEK
WEVKDANFRYALDLIKYIRKTYGNHFDIGVAGYPEGVDDTTDADEHIKYLKEKVDAGGTF
IVTQMCYDADIFIEWVKKVRAAGIPESVPIIPGIMPISTYAAFLRRANWSKARIPPEWLE
VLEPIKNDDSAVRDAGCDLIVEFCRRLMDSGIMHMHFYTMNLAAAVRMVLEKLDLTPPAE
SPHPDIKPLPWRQSLGLNRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
GLDEYGIGLKGTNENNRKIWGEPKNIKDIVGLFVGYMRGKVESLPWSEAPINEEANTLVD
DLVALNSRGLLTINSQPAVDGVKSSHPVYGWGPRNGYVYQKQYLEVLVSPDLIGTVIQRM
EQDPDITYYAVNCNGELKTNAPTDGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYH
LGVEWSKCYEEGSESRKVIKEITQSWFLVNIVHNDFRQQQGIFPIFDGLKVPGLDETPYT
NGVTNGVNGINCVNGVNGHAHNHGKPETNGVPDGNNVVNGADKASSNSTLKN
>A0A7Z0IQT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides panzhihuensis|TrEMBL
MDLQQRISDRAGEILLFAVTPPRVTTDPERVQQIAEVTLERIRPLDVDGLILYDIDDESD
RNPEQRPFPFVRTLDPAEFLERNLADLDVPAVVYRATGKYDEGELRDWVKTQDPAKALSV
FVGASSGEKRVSTSLRRAHEIRNETNPDLLLGAVAIPERHTAKGDEHLRLIAKQEAGCSY
FVTQVVYDVNAAKNLVSDYRYECETRGLEPVPLVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENELRHAADTLDASLEQAEATALELMSFCRQLGVPFGINIESVSIRKVEIEASVRLAERL
RAKLAR
>A0A854EYQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cenocepacia|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAAIATRTICERLAV
>A0A8E5IM77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Dessau|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1Y4TFC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. An121|TrEMBL
MKNAREILKDRVLLFDGGMGTYYKARPGLECEQANLEDPAGILAVHREYLAAGAQALKTN
TFGLPRMAAAHVPGWQQLARAGWELGAQALAEAGGEGALFADMGPAPDTEADPAAQSYKA
VAEVFLELGAENFLFETLSSDAGLAEAAAYIKSRRPDAFVLVSFAALPDGYTREGLSCRE
MAARMAACGQVDAVGLNCLLPPGAMAPVLQGVAGCGLPVSAMPNGGYPLVTRSRVVYRGR
PDYFAREMCRIRAGGAVILGGCCGTAPAHIAALRQALEETPMPICGTEAPAPQPEAQILP
AVSDPFLRKLARGERVIAVELDSPRDADLTGYMASARRLQQAGVDALTIADCPIARARVD
ASLTACKLRRELGLVAMPHMTCRDRNLNAIKALLLGLYAEGVREVLAITGDPIPTAERDE
VKSVYQFNSRKLARYIHALAGPGEALPGMTVFGALNLNARNFDVELRRAQEKQDSGMAGF
LTQPVLSARAVDNLRAARAALPGAKLLAGIMPVVSHRNALYMENEINGIHVEDSIIRRYE
GADRARGEELGLEISLEMARAAGPWADGFYLMTPLGRVGLMEKLVQAIRREGL
>A0A836TIV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinaceae bacterium|TrEMBL
MKIIDIIRQGKPVFSFEFFPPKDIDGFDKLFKTIDNLKSWNPAFVSVTYGAGGSTRSKTI
DLVGRIKNDIGLESMAHLTCVGNSSDEIFKTLESIKKQNVDNVLALRGDPPSGEENFIKP
ANGFGYATELVQFAHENFSFCIGVAGYPEGHPESLNREEDLIHLKNKVLAGASFIVTQLF
FDNQYYIDFVDNLRKIGVDVPVIPGIMPILNLKQIKKFTKMCGASIPKDLMARLEKVQGD
PESVYKIGVDHATDQCEKLLKEGAPGVHFYTLNRSRATLSVLERLRFPK
>A0A6J5JTH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cenocepacia|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVM
>K0JTZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764)|TrEMBL
MTSVVERLSGGTPVFSVEFFPPRDDADEQVLWRAIRELEGLDPAFVSITYGAGGSSRDRT
IRTTGRVVQETTLVAMAHLTAVSHSVAELRNVIGWYAAVGVRNILAVRGDPPGDPHGEWV
PHPDGLTYAEELVRLCRELGDFCVGVSAFPYGHPRSGDLDTDLKHLINKLRAGADFAIAQ
LFLEPEHFLRLRDRIAALGHETHLLPGLMPLTTPRTLAKCVELSGAPLPVSVARRLEPLA
DDPKAFRSAGVDLVTEMGERLLAEGVPALHFYTFNRSKATREVVGRLGLVPART
>A0A2T3ML85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium iliopiscarium|TrEMBL
MVNQALTTQTESELRVRYNDITRGVYFIGTTPPKTSTPLDEVEGIADRLVNRIKDLAIDG
LIVYDIQDEVSRTKKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSETEAFDEWL
NEAWHEYQVRDIVLVGSPSAKNEVSLPLSTAYQTLAEHQNNFFTGGIMIAERHAKKGNEH
ARLIEKYQQGCNFFISQAIYDTQATIDILTRYAIECKQDGIKPQRILLTFSPCGSAKTLE
FIEWLGVSVPEATSLRILNATNPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRK
EEIDGSILLYKLLRASMDSHLAKHEFRTLQRNTIAAQ
>A0A1L9CSC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium pusense|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNAEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLATAAHLTCVDASRDEVHQVVDEFRNAGVRHFVALRGDPSTGIGTAYQ
PHPQGYENAAALVKGLKELGDFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPAFLDERFEGYD
EDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A0D2FEF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phialophora americana|TrEMBL
MHISKKLAQAHQSNKPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
QLTCEMVNAAQSHYGLETCMHLTCTDMERTQVDDALRRAYKAGCTNILALRGDPPRDQEK
WEAKDGGFRYAKDLVKYIKTRYGDHFDIGVAGYPEGCDDHRDVDVLIDHLKEKVDAGATF
VITQMFYDVDIFLDWVKKCRNRGIDIPIIPGIMPIHTHAAFVRRAQWTKCHIPEDWYKAL
EPVKNDDAAVRAVGKELVAEMCRKILDAGILHLHFYTMNLAQATRMVLEDLSITPSTSGM
ALEKPLPWRKSLGLNRRDETVRPIFWRNRNASYITRTADWDEFPNGRWGDSRSPAFGELD
AYAIGLKGTNEANIKLWGKPKSLREITSLFVRYLQGDLDRLPWSEGAISAEADSIKDDLL
SLNKRGFLTINSQPAIDGASSTHPVHGWGPAGGWVYQKAYLELLVFPSIFKEVMERLDAN
KNLTYYAVNQKGELLTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WSKCYPAGSGSRKLIETIMGECYLVNIVNNDFHQTHEIFKVFEGLEARDLDLVFDGTDAS
DHVNGTNGTREVLNGDSPVAEVEKSIANGEEHKVPFPTNGGALKN
>A0A5J4T1K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
MKVTDLIYNNRQTAFSFEILPPLKGNGIGKLYHTIDVLKEFDPKYINITTHRSEYVYTDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITAVPHILCSGFTKEETEYVLIDLQFLGITDL
LVLRGDKAKHESVFTPEENGYTHAIELQEQINNFNKGIFIDNSKAREMTVPFSYGVACYP
EKHEESPNIDTDIYWLKKKVEAGAEYAVTQLFYDNRKFFGFVEKARQAGINIPIIPGIKP
FKSLSQLTMIPKTFKVDLPEELSHEIRKCKNDNEACRVGIEWCTVQCKELIAHKVPSIHF
YSIAATDSIKEVAKRIY
>A0A5N6J237|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus minisclerotigenes|TrEMBL
MHIKEKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAAEGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFINWVKKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIKDLSRLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLIE
LNNRGILTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDSWYLVNIVNNDFHNTYDLFELFKDLNVRDFDVELAADNADLK
SQENETAETTAN
>A0A1E3RIC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium flavescens|TrEMBL
MTFGPCGGVRPDGQCEMRAGPCIFGDVVPWSGELTEPPPVTAPLVLTDFSCLPFDEKDVA
ATAALLAPSCDAVLVGEHQNRPDFPPTLMGALLLDAGVTPWITLSCRDRNRVVLEQELRG
LRQIGVTTAMCVTGDGRAYDVRPDVTQTFDLDGPRLVSLAASLGVAAAVPETPTAPPVAA
RPRRLVEKQRAGAGIAVLNHVPFPYMVADFMTAARAAGLTIPVIAAVAVFTDELSAAVLQ
GLPGLELDPAVTETVLGAADPVAAGIDAAVEEARRLLSIDGVAGVNVSGLASASGTRVGA
EIKAEVGRRIQAQTASLNR
>A0A0B5I913|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces vietnamensis|TrEMBL
MALGTASVRSDRARTVREILASGETSYSFEFYAPRTEKGEQVLWNAMRRVEAVGPSFVSV
TYGAGGSTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNILGQYADVGIRNMLAVR
GDPPGDPLGEWVEHPEGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSLDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVEKAGCETPIIPEVMPVVNVKTLDRLPQLSNAVF
PADVKERILAVKDDAAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A545SXG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exilibacterium tricleocarpae|TrEMBL
MSNEQDLRLSFEFFPPKTAAGHEKLSHVCDRLAEFAPAFFSVTYGAGGSTRDNTKGTVFS
IKEKGLQAAPHLSFGGDSEADIKALLSEYRAAGIDRIVALRGDMPSGMGGASHLVYANQL
VEFIRRHFNDQFHLEVAAYPEIHPEAKSYDADIEFLQGKFDAGANSAITQYFYNPDAYFY
FLEQCRQRGITQPIYPGIMPITNFKNLARFSDNCGAEIPRWLRKRMESFGDDKDAVKALG
VELVTELCETLLDNGAPGLHFYTMNQAEPTATIVRNLGLAGDD
>A0A101DJG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfonauticus sp. 38_4375|TrEMBL
MQIRELLTQRDFFISLEFFPPKEKEKWSDFFAEVKNLKQINPLFVSVTYGAGGSTQDYTL
EIVKILKQDFALEPMAHLTCVGAKEENITFFLESLKAAQVENILALRGDPPRGEEKFVPD
SERFKHASDLVQFIREKEGQGFSLGVAGYPEGHVEAKSLEEDLNYLKLKLDLGGDFVITQ
LFFDNNLYFDFVSRARKIGIDKPIIPGVLPIMSLKGIKRIVNLCGASIPQELLTELEEAE
KKKGSAGVIEVGIKQAQKQVQGLLEGGAPGVHLYTLNKSQACLEIVKNIL
>A0A653B5F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas oleovorans|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLTLYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRNETGDHFHIEIAAYPEMHPQARNFESDIANFVRKAKAGANSAITQYFFNADSYFH
FVERVQKLGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVESIQAFG
QQVISEMCERLLDGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A7I0ELL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TmT3-12|TrEMBL
MPTTSDPACGNIPFSFELYPPQSDAATSALHATILRLAAAGPDFISVTYGANGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSNAEASQLIREFLDAGVRSFLALRGDPPEGAREGEAF
LGDLGSAAELVQLIHRVQAEREPYRESVIPGLPAARSITRERNKVRIAVAAFPNGHPRSR
STAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRQATALARELIAGDAPGLHLYAFNQHE
TVLSVLDGCGLLTPTSSASAPSASAPPASDPAKEYS
>A0A3B8TS30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSNQSRISFEFFPTKTDAGHEKLLATATQLATYNPEFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKEDLRELLHLYKDAGIKRIVALRGDLPSGMGMANGELRYANEL
VEFIRHETGDHFYIEVAAYPEMHPQARDFEVDLQNFARKVQAGADSAITQYFFNADCYFY
FVDRARKLGIDIPIVPGIMPITNYSKLARFSDSCGAELPRWIRKQLEAYGDDTASIQAFG
AEVITNMCERLLEGGAPGLHFYTLNQAEPSLAVWDNLKLNR
>A4IL00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus thermodenitrificans (strain NG80-2)|TrEMBL
MGLLDELKQRVLIADGAMGTLLYSHGIDRCFEELNLSKPEEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPSINRAAVRLAKQAANGRTHVLGTIGGLRTLNKSAVPLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLTIARKETTLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLQSLEEVPLPTRAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIEAMARALQDRKPVTKKTVKRRAVSVS
VQADNPSAVTPLSELARTRRSVIVELDPPKQLGIDKFLVGAKALHDAGIDALTLADNSLA
TPRISNVAVGSIVKEQLGVRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLISQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVER
MEKKIQCGAHYFLTQPVYSEEKIVEVYEATKHLHTPIYIGIMPLVSARNADFLHHEVPGI
TLSDEIRARMAACGNDPVQATREGIAIAKALIDAAFDLFNGIYLITPFLRYDMTVELIRY
IHEKEAAAKERKVVHG
>A0A844D2W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella rivi|TrEMBL
MDNPNFSIEFFPPKTAEGAEKLRVTRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILA
AGEQAAPHLSCVGGTRESIREILGEFKSHGIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGDWFHIEVAAYPEVHPQAKSPQDDLLAFERKIKAGANAAITQYFYNADAYFQFVE
QTRKLGIDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTALCERLLQGGAPGLHFYSMNQAAATTALWQRLV
>A0A1I8FDL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
VDGRARVHHHASCSSIRPTSSASCPTAGGSASTAPSSPGVLPVQGYQSLRPHRQAVQADG
PDSMLRVIEPIRDNDEAIRNYGIAQCTQMCQELLQSGQVHGIHFYTLNRDAATIRILKNI
GLWREDLPRPLPWQPSANYERWRPRPCDPCSGPRRPTSYVHRTRHWDDYPHGRWGSECAE
IGELRDYYFRASKQERLRMWGSEPTSEPDIWRVFASHLSGKPVSPDGVRVTRLPWGDEEP
LPSSSESNEAAEARQRLAGLSERGLLATNHLLRVNGASSDHPVHGWGGSGGFVYQREPTW
SFSCPAAGCQRCSHGGGRVSFHIADRSGNVNLANFSEPIALTWGVFPASEVAQPTVCDGA
AFLAWRDEAFALWTEEWGRLYEEGSPSRRLIESVAETYLLVALVDNDFTEDTVSVLWDLT
DQVARRRPTARTRWSSLESLFTWAGSPGLLTWLAHLAGSPGLAHLGWLTGLTHLGWLTWA
CSPGLAHCWGLTWAGHLG
>A0A356D013|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLISFIKKHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A261E8U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. A35_P|TrEMBL
MGFHSARQVEALNQSLADLSGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPEMYATDLVALLKAEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDDDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYVICHTLGVRPKGQP
>A0A3D3D923|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKISNLFNSGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFISVTYSAGGSGSKSRT
CEIATKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENILALRGDMVEGVEPQKD
FTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRKKVESGASHLISQLFFDN
SAYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGASLPAKFAKIMQKYDTRPEA
LRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEAVSSLL
>A0A1E7JAK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium C00003063|TrEMBL
MSSFKKSLDSGKFIVTCEVAPPKGINLEKTAHHIDLLKDKVDAMNLTDHQSSVMRYPSLG
GALMVKEMGGEPILQMTCRDRNRLALQGDLLFAASRGINNVLCLTGDSVMLGDHKTAKGV
FDLDSSQLLAAIRILEKGKDLGGNDLDGSPVFCAGAIVTPEANPIEPQLIKFEKKIEAGA
EFIQTQAVYDLVRLKTFMEYARQFPVKILAGILLLTSAPMARFMNKNIAGVNVPQTLIDE
ISQAPKGGAIVKGIEIAGRMIRTIHTEKICDGVHIMAIGKEELVPDIMAAADLTS
>A0A1E4CSP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp. SCN 65-11|TrEMBL
MKSVQQLHERRSRLVGDGEITVSFEFFPPKTERMEEALWTSIRRLEPLAPEFVSVTYGAG
GSTRERTHATVARIVKETKLAPAAHLTCVGATREEVDEVVRGYWDAGVRRIVALRGDPAA
GVGARYEPHPGGYESTADLVRGIKAIGAFDVSVSAYPEKHPESATVDVDLDTLKAKIDAG
ADRAITQFFFDNAHFLRYLEAARKRGIWAPIVPGIVPIHNFKQVSGFAARTGASVPAWLA
RRYEGLDDDPATTHLVAAAVAAEQVIDLVDEGIRQFHFYTLNRADLVYAICHLLGLRPQS
TGAGSVVAKGAA
>R6QU75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:352|TrEMBL
MKLSELLADNKTVLCDGAFATFYSKLTGNSERRCELENINNPEIVKRIHTQYINAGAKII
RTNTFSANTAILNISQDELIKVIKQGYMLARECAGENAVVCADISAIYTNDDHDKNPDAE
YRAIIDAFIECGADSFILETLPSIDIIAYPIEYIKSKKPDADIYLSFAIMPDGFTRSGVS
LNSLLDSIVKYKDKLCVVGLNCGCGPTQIQRHAVQFNDFIKSNTKLYTAVLPNSGYPYLE
RRRIAFSPNTEHFVDEIARLIPNNINILGGCCGTEPEHIKLLSEKLNGNISFEKIEIKET
KKSSPAPFSSRIANSDFVIAAELDPPYGTDLNKLINGANLLKEAGADIVTISDSPLGQVK
MEPVLCSARIHRECEIDALPHICCRDRNINALRSVLLGAHSEGIRAVLAVTGDHIAESDR
GVVKPVFNISSTQFMTIISEMNKEVFADSPILIGGAFNPDLKYAKSQLKRLEKKMECGAT
FFLTQPVYSAENIDVIEEARSLGAKMLVGIMPLVSYRNASFLNNEVPGINIPQDIIERFS
PNMTREESSAVGTEIAIELAKTYMTHADGFYFMTPFNRAEIVCDVINALPLKN
>A0A1B9F6K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dissulfuribacter thermophilus|TrEMBL
MKKDHDFKYTFELVPARASRGKALDDIISFAQKAVDDGILSALSITDNAGGHPALSPTAL
GREIQTLGITPIIHFSCKDKNRNLIESQLFELDRHGLRNLLVLTGDYPRYGYKGIPKPVF
DIDSVVVLEMISQMKKGFLIDPRAPGGGTRLSPMPFRPGCVVSPFKRLEGELIGQYLKLK
KKVESGAEYVITQMGFDARKFQELLFFMEEAGIDIPVYGTVFLPSPRLARAINKGVVPGC
VLPDELLSRMESWKGPGKRDRLEFGARLIAVLRGLGYNGVHISGPGLAYEDVAWMINRSE
AIKDLWWDFIGEFEFPHLWEFFLYEKDEKNGLNKRERTKTQRTKLPIGEYLSYRTSSFVH
ELFFEEGKYLFGPTKTLIRLLEKGGLNGVLTSFEKAVKAPLYECQMCGNCVLTEFAYLCP
QSQCAKGLLNGPCGGSRDGWCEVWPGEKPCFYVRVYKRLRALEQQCTFLKHTLSPRDWEE
WKRSSWVKVFLKKRVDKVPS
>A0A1Q5JII9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02261|TrEMBL
MALGTASVRSDRARTVRDILASGGTSYSFEFYAPRTEKGEQGLWNAMRRVEAVGPSFVSV
TYGAGGSTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNVLGQYADAGIRNMLALR
GDPAGDPLGEWIEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVAKAGCETPIIPEVMPVVNVKTLGRLPQLSNAAF
PDDVKERILAVKDDPTAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A7S4QBD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alexandrium monilatum|TrEMBL
RTSESYPPPPPAASLAMASFADDAKIAELVANSPPGWFSFEYFPPKTDEGVANLRKRIVR
MKALKPLFTDFTWGAGGSTSELTLQLTSAAKNEFGCVANM
>A0A014M3I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia mallotivora|TrEMBL
MSFFHVNQREVLNQSLAELNGQINVSFEFFPPHTNEMEQTLSASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWDNGIRHIVALRGD
LPPGAGKPEMYAADLVALLREVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGATRA
ITQFFFDVEGYLRFRDRCVIAGIDVEIVPGILPVSNFRQLQRFAALTNVRVPGWMNSMFA
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPEKSAQP
SMAASEH
>A0A350IH00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rikenellaceae bacterium|TrEMBL
MKISEILKNSKKAFPSIEIVPPLNGMDKEELLNTVKTFMEFSPKYINVTCHRDEFSFRKE
DNGTYTKHLVRNRISEVAVCAAIMSKYEIDVVPHIICGGASAEELESDLYNYKFLGISNV
MALRGDSISGEKRFTPHPHGYKHANELVSAIRKFDEETAGESFCIGVGGYPEKHFEAANI
ETDIENLKRKVDAGADYVITQMFFDNEVFYRFERQCREAGINVPIIPGLKPLSTAKQVEL
LPQSFSLDIPKVLTERIAHAGDDKDAVYEIGLDWCMEQCKDLLKHGVPAVHFYTMGKTKN
ITAIMKECF
>A0A3R6RG46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium AM27-36LB|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGKDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKAAEI
>U7KII0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. KPL1986|TrEMBL
MSPRFSASAPLDSMSEEELMVPERLALSFEVIPPRHDADEAKIDRLLETLESYHPDYIAV
TSSKRSGWLEGTTAFIERISRTTSMRPLAHLACTAGSRTELIGWTNRLVDAGVRGLLALR
GDLPEEGLPEHYPQHADELISLIRQLERQQAARFAAGRLAVGVACYPSGHVESKNEDEDF
DVLLKKQRLGADFAITQLFFDAQDYLRFTKKAQLAGVHIPLIPGIMPMTSLRRVERMGEL
SGLAVPERVRSALAAATTPEEEYETGMELTAELARDIVAGGASGLHLYTHNNPDNTHDLL
TRIGVDNDQR
>A0A4Q2RYH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides oleivorans|TrEMBL
MDVATRIRSGQGDFVLFAVTPPRQSTAPERLPEIARATVERLDRLDLDGLVLYDIDDESD
RNPAERPFPFSPTVDPSDYRTEHLRSWRTPAVVYRAVGKHQRDDLRSWLAAQDPARTLTV
MVGASSRDSSTPVSLADAQAMLAEVNPDLLLGGVAIPERHSRREDEHLRMIAKQEAGCRF
FVSQVVYDVNATKNLVSDYRYECEAQGVTPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLRHAANPLRASLEQAASTAAEIADFCRQLGVPFGLNVESVSIRREEIEASVALAARV
TPLVRLA
>D3F6X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Conexibacter woesei (strain DSM 14684 / CIP 108061 / JCM 11494 / NBRC 100937 / ID131577)|TrEMBL
MSARYEILPFGAWEAEAAAVAPVTLTITCSPRLGVEHTLTVAERARALGHRVVPHVAARM
VADRSHLDTLMERLAAAGIDDVFLIGGDAAAPAGAFDSAVELLPLMHAHELRPRRIGIGA
YPEGHPLVDRATLADALCRKAAFADYMVTQLCFDPAALLRWIEQTRAAGVDLPSYVGLPG
AVDRRRLLEVSMRVGVGDSIGFLRKQRGIRRLLSRPERAVERLGAAFAPLVGEPELAIEG
LHFYTFNRLRATLAWEAQRGSADGARAESACDA
>B5ZEV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / CCUG 37298 / CIP 103539 / LMG 7603 / PAl5)|TrEMBL
MSLNPSADTPSPLGMSFEFFPPRTDRMAETLRQTVASLVPLAPRFMSVTYGAGGSTRDRT
LDIVASLVRETTVPVAGHLTCVDASRDQVDAVARAYWDAGVRHIVALRGDPAEAGAAYVP
HPDGYANAAALVAGLHRIAPFEISVAAYPETHPAAVSAAADLDNLKAKIDAGATRAITQF
FFESETFLRFRDHAASAGITAEIVPGILPVGNIAQAYRFADMCGARVPDWMRRLFDGLDD
QPGARAIVTTTVATELCRRLREEGVDHFHIYTLNRADASLALCRLLGR
>A0A4Q2S665|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides oleivorans|TrEMBL
MRELLAQGGRSFSFEFFPPKDEAGEQQLWQAITELEPFGPTFVSVTYGAGGTTRDRTVAI
TARIARETDLLPVAHLTCVGHTTDELDAVLDELGEAGVHHVMALRGDPPDGPGSPWTSTE
GGLTYANELVALVRERHGMRVGVAAFPEGHVDAVDLEQDAKVLKAKQDAGAEFAVTDMVL
RASDYVGLVERADAVGADLPIIPGIMPILNLRSMERMVEFSGRDLPAETVARLQPLADDP
PALRAEGIAIATEQCAQLLDAGAPGLHFYTLNRSKATREIFANLRISA
>A0A369W8L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterium lacus|TrEMBL
MGPTRAENRLSRQPESRLPEIAVSFEFFPPKTDAMEERFWDSLARLAPLKPRFVSVTYGA
GGSTRERTLRMVSRITTDSGVPAAAHLTCVGATRAEVDDVVRGYAEAGVSRIVALRGDPP
AGVGQPFAPHPEGYQNAADLVAGIRKLGDFDISVAAYPEKHPQSLDWDAEIDNLKRKLDA
GAARAITQMFFENADYWRFVERAQKAGITAPIVPGIQPIHSFKQISGFAGRCGALIPQWL
ADRFEGLDNDPETHALVAAAVAAEQVTELLDSGVTEFHFYTLNRSNLVLALARLLGIRPA
>A0A8D9KRK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 8 R 14|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISNMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A8J5KNY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MDPSSKKIYVMKFEVSKFIDLCILSGCDYCDSIKVLDFEFLVVMINFVGFHISRGEFILR
KNIFVCMETIMHLTCMNMPVEKIDHALNTIKANGIQNVLALKGDPPHGQDKFVQVAGGFA
CALDLVQHIRAKYGDYFGITVVGYPKAHPDMIQGDEGATLEAYNSDLAYLKRKTLSVVLK
FWKSFSHVKILELCEIFILWSAIREA
>A0A4P7CRK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia pallida|TrEMBL
MKPIELSFEFFPPKTPDGVEKLRATRAQLLTLKPRFVSVTFGAGGSTQQGTLDTIVDIAK
EGVDAAPHLSCIGSTKESLREILRQYRSHGIRHIVALRGDLPSGMGEMGELRYASELVAF
IREETGDAFHIEVAAYPEYHPQARSPRHDLEAFAKKVKAGANSAITQYFFNADAYFRFLE
DARKLGVDVPIVPGIMPITNYTQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTDLCRRLIENGAPGLHFYTLNAAGATKAICERLDL
>A0A2T2XJS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfobacillus benefaciens|TrEMBL
MAAELGLRLRHGMVMVADGAIGTGLLANGASVHDLPLLPLQSPDSVFQLHLSYLEAGSQI
LETHTFQANASKLASLGLGADIFSLNRRATQIARHARDTHGEEAYIVGSLGPLATPVDPP
WGTGTAYTDAVSMYQEAVSGLLAGGVDGFIVETMSDALTVQAAVEAIRRESSLPIIVTFA
FSPMGTTLFGLSPEEAMDFVAALPGGPPDLVGANCGSGPAPLLDAILRMAPKAREQGIGL
AAYPNAGEPTRRGDRIHYPASAEYVGNIAPALKSAGCVVIGGCCGTTPDHIRSISHALSS
TATPEIEPWSTVTLHEGPSHETHENSAAPASLSDLFGKHFIISVELDPPRGVTVTRTLEA
ARRVHAAGADLINIGDSPMARVRMSSLATARLLQEQTGLQTIMHFTTRDRNLMGLQSDLL
GAHALGIRNVLCLTGDPPGLGDYAHATAVYDLDSIGLVRVLKSFNQGQDALGQPIGASTH
FVMGVGINPNSEDVKLEIERLRAKMDAGAHFLMSQPVYDPTILYRFFDQVPDITGIPLLL
GVMPLVSYRQALYLHNEVPGIDIPSVILEQLAGSSEAAKVGMELALDLINQLGSLVAGVY
LVPSYNRVDNLVPLIEYVRRTFDSAACAHP
>A0A7W8YKD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. S3M3|TrEMBL
MNACVDYKALPLPASHITHAYSLEVGAKDIAALTAAAPRILPGSTISIPYLPREDNAARL
AAVQAVRRLGFEPMPHFSARRIASLAEFETFVSRAAAEAGVERCFVIAGDPSTPMGPFSD
STSLIETGVFERSGIKLIGVGGHPEGHPVMSTEEQWEVLERKCHNIVQRGMTPLIVTQFA
FDADIVLTWLTALRQRGINHPVRVGVPGPANIAVLARYAALCGVSACASMWSKYGVSIGK
LFGTAGPDLFVDRLATSLTAAHGKVSLHFFPFGGIAQSVKWVEQYRGRD
>A0A8J5KYW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MVLEIGRSPAGNPLVKGKWFETGHVLGVLLASSPLLEQAWTRCLCANVGSSSFIIDKSDD
AVFIAFSRAQVAASPSDLGRGFFEPVSLYSSTHKLLALLGRGKEDSGEKPQPVLLQAPYE
EEAQCAALCKSDKVCMETIMHLTCMNMPLEKIDHALNTIKANGIQNVLALKGDPPHGQDK
FVQVAGGFACALDMVQHIRAKYGDYFGITIAGYPKAHPDMIQGDEGATLEAYNSELAYLK
RKTLSVVLKFWKSFSHVKILELCEIFILWSAIREA
>A0A151Y0I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pragensis|TrEMBL
MPLFYNCLKERQFCFLIEYLPAVKPAVPACSELAGFPAFMTLADRVQSDDDLAPLDAAVH
FPEADPLLHYSGKGRDIAEFETFLEQAKAKGHSSLLLLSGDKLKKHNDGAENAALRSRYL
ESVNMVMAARRDPFFNIGVAFNPFKYAQAERDAQYFKLQKKLKAGADYIITQLGCDLDAL
KLAKQFLDEKHYRPPILACVMPLTFSRAKFMARQKVAGIVLTPHVLQLLEQEHVQDKHLA
ECKVYERCALQILICRHLGFAGVHLSACHKADEQQKLTEALFRLQSLSLNECEQRWQALW
QLETGKELQPEVNSVNHAAPISHVMKYKQMHAMHELMFSSRIAKGVGSLIFNAKLWNRPL
AEEALLKTEFISKHSVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTHLDRCEFGDR
ECIHSVKARLAKAVHQTDILKMELIPSVAIETRNTSSWKNWFKTQA
>A0A2G9XLK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacteraceae bacterium CG23_combo_of_CG06-09_8_20_14_all_50_8|TrEMBL
MKNDKKFTDQIEGGDFIVTAEYLPKAETEGSAVKAALLSLKEVPSAVTVPDNSIGVALSS
LAASILLLQAGVEPICQVVTRDRNRIALQSDLLGAAALGIRNMLCLSGYHQTLTDSPESA
NVYDLDSTQLINMIQKMRENGELLNGEKIGGPFPIIAGAVANPYLKPIELNIIRLAQKVE
AGADFIQTIAVFDVDEFKQWLDVAREAGIADKTAILAGVFPLESAEEAESLCSKYTEFQI
PASVIERLKSAGDKQAQKKEGMAICIETINKIMNMNGLHGIHILSGGKEESIPEILSASG
LSGKR
>A0A453M814|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aegilops tauschii subsp. strangulata|TrEMBL
MPSVFQLQVEHIKAKYGDYFGITVAGYPEAHPEVILGEEGATEEAYSKDLAYLKRKVDAG
ADVIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTKIPAEIT
AALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNLGLIEES
KLSRTLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWGDSRNPSYGALN
DHQFTRPRGRGKKLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPETTIIDD
QLVKINSKGFLTINSQPAVNAEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKS
KAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEI
WSRGWACLFPEGDSSRELLEQIQKSYYLVSLVDNDYISGDLFAAFKEI
>A0A3C0GQQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTASKLKAFAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYASELISFI
RAEHGDAFRIEVGAYPETHPQASDALLDLKHFKTKIDAGADAAITQYFFNADAYFHFVDA
VRKLGVSVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDAESVRAFGAEVV
AGLCERLVAGGAPGLHFYTLNLARPTTQVLKLLRG
>A0A4R3YTT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter rhizovicinus|TrEMBL
MPAISFEFFPPKTDEQRAQLDTTVRKLKSHAPDYVSVTFGAGGSTLSYTDETVKRLRSEH
ALSVAPHLSCMGGTRAEIAALLDTYRETGCRRIVALRGDLPSGMASPGDFRYAAELVSFI
RKHSGDHFHVEVAAYPETHPQAENALKDMQHFKTKVDAGANGAITQYFFNADAYFRFVDD
ATKLGVNIPIVPGIMPIANFSQLQRFSEACGAEIPRWIVKRMQAHGDNAAAIRELAADVV
AELCRRLLDGGAPGLHFYTINRARSTTSVLERLG
>A0A1H8TQH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquisalimonas asiatica|TrEMBL
MESQKKHSPVFSFEFFPPKNEDGEERLRKTRERLQALGPRLFSVTFGAGGSTRERTFETV
VDIQKRSGIDVAPHLSCIDATPDSIRELLSRYRENGIRNIVALRGDMPSGTGGGPGHFKY
ANELVEFIRQEHGDHFHIEVGCYPEIHPEAKDAFSDLENFKRKVDAGADSAMTQYFFAPE
GYYRFVESCEKMGIDIPLVPGIMPIVNFQQLARFSDMCGADIPRWLRKRLEAYDAKGDKE
SMQAFGIDVVTAMCADLLDAGAPGLHFYTLNQAKASETIWNNLGLTQKQKAAAAD
>A0A165WNG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHADHPVYILGTIGGLAGDTDATVQR
ATPATIAANVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFEDLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFVGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A199QKI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum|TrEMBL
MKLKQALQQRILVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIQAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAVTAREHADHPVYILGTIGGLAGDTDATIQQ
ATPATIAASVTEQLTALLATEQLDGILLETYYDLPELLAALKIVKAHTELPVITNVSMLA
AGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPTNVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSSRSIVAHNQ
PTAKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTMIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TAVSTKSISRKLSYGCDYIITQPVYDLANVDALADTLAANHVDVPVFIGVMPLVSRRNAE
FLHHEVHGIRIPQAILDRMAQAERTGHERAMGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVNYVQAKNLIKVQ
>A0A8H6QVN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus felis|TrEMBL
MEKITDKIAALPPDENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNRDFTFAVDLVRYIRQKYGDYFCLGVAAYPEGHPVDSYQDVQDPVRDLPYL
VEKTLAGADFIMTQLTYDIEAYTKFEKMLRDHESGAFKTIPIIPGLMPIHSYKILTRTTK
LSHVQIPPQIMSKLEAVKHDDDAVKRIGVDVLTDLVEAIRKIPCSGFRGFHFYTLNLEKT
VSFIIERCGLIPDDPEDFDAIADDDYTTAPTGAQNRSLFRRRASSVNSLPHNRVIVDRLQ
VPSDGSSRASTTHEAPATSAGMPAMPPDRNTTLLISEGQGALGREATWDDFPNGRWGDAR
SPAFGEIDGYGPSLHVSGTVARRIWGYPVSREDISALFRRHVSGDLYIVPWSEGGAEENS
SGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEF
FCPSKDFQTVLKPLFAKHGHEKLAWFATNAKGEFESSLPADPADADTIEMNPNNVNAVTW
GVFRGKEIVSPTIIEEVSFRAWGEEAYRIWDEWRRVYPRGTPTERFLDGVKNDVWLVCVV
GQDFGAGTEGGSEEEQQETKWMWNVLINGQ
>A0A7H8JMN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NA04227|TrEMBL
MALGTASTRTDRAHTVRDMLASQATTYSFEFHAPKTPKGERSLWNSLRRVEAVSPSFVSV
TYGAGGSTRDGTVKATQQIVADTTLTPIAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMAEWVPHPEGLTYASELVELIKESGDFCVGVAAFPEMHPRSAREDEDVRHFVD
KCRAGADYAITQMFFHPESYLRLRDQVAAAGCETPIIPEVMPVTSVKMLERLPMLSNAAI
PETLKERILAAQGDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHTPA
>A0A7J3JVJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurococcaceae archaeon|TrEMBL
MSNCPKNMLNGPCGGYRGTQCEVRGECVWVKVYISLHDHSRRYEVFTKVNLKPYFKLRSY
YPPSRRALSKFMTLLNRGKAVVYEVFSQPLTQDIPNLLNMLSKLSDYVDVYTIVDSPMGL
KTYDQLALALLIKNYLKEHDVMINIASRNKSVDEVTSYLLTTLNCDIRNYLIVTGDWPKK
HVNTFFEVDSTQLVYLSRILSDLGIDYSGRQVNLGSRPAHIGVVANQYSNYLDLEVLRCV
RKLKAGAEFIVTQPVYDVDRFKKFARSLRNYDQDAKLLATYAVIDDVERLNILKALGIVL
DELERERIINLLRSNDVIDANEIMFKEVLEGVKDLSSGFYISTYGNNEVTLKFLKRVRTH
IMSL
>A0A7L1AYI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gymnorhina tibicen|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETVLHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A2W6RE30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MASPASLNLAEARALLLSPLGPVARAGSNQDAVRVSFEFFPPKSDEAEANLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIIAETSLRPAAHLTCVEASRDEVDEVIEGYKTIG
VDHIVALRGDPPGSTGIGGAYRPRADGYANATELTAAIGRVGGFDVTVGAYPEKHPESPS
IDHDIAVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGIMPVSNFAGLT
RMCGACGASIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFQDFHFYTLNRAD
LVYAICRVLGVRETAS
>A0A4P6LE25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. WH 8101|TrEMBL
MVSALQRVLLSGEAAITAEVMPPRGGDPSHALAMAELLRGRVHAINVTDGSRAVMRMSSL
ALCRLLLDAGHEPVLQMACRDRNRIALQADLLGAHALGIRNLLCLTGDPVKAGDQPGARP
VNELESVRLLQQVTAFNSGMDPVKETLADGPTSLFAGAAADPHASSWSGLSRRLERKRKA
GAQFVQTQMVMDAAVLERFCRELAAPLELPVLAGVFLLKSARNAQFINRMVPGACIPEAL
IERLANAENPAAEGVAIAAEQVRRYLGIAQGVHLMAVKAEERIPEILRQAGVSSDAVNFQ
AVKSQAVKSLQS
>A0A3B8UGL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRNAVNVSFEFFPPKTDAAEANLWSAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIEGYKAIGVDH
IVALRGDPPGSSGIGGAYTPRADGYANATELTAALSRIGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLKRMT
AACGAALPDWLAGHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAVA
>A0A101NRE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cellostaticus|TrEMBL
MALGTASTRTDRARTVRDILGTGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTTTVKETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPSGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSLDWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVEAAGCDTPVIPEILPVTSVKMLERLPKLSTALF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A315EXD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. Rim8|TrEMBL
MNANNSLSIEFFPPKTPEGAEKLRVVRQALYPLQPQFCSVTYGAGGSTQAGTISTLKEIL
SEGVPAASHFSCIGATRDSVRQQLAEFKAMGVKRLVALRGDLPSGYGAGGEFHYASDLVA
FIRAETGDDFGIEVAAYPEIHPQAKSAEADLQAFATKVKAGADSAITQYFYNSDAYFRFV
EDADKLGVHIPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLLGFGDDLASIKAFGLD
VVTDLCDQLRAGGAPGLHFYSMNQSVPTLAICKNLGLGV
>A0A519J219|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MTAPSPSRTTLAEARALLLSPLGPVARAGSNRNAVRVSFEFFPPKSDEAEANLWSAIRRL
EPLNPAFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIEGYKA
IGVDHIVALRGDPPGGDGIGGAYAPRADGYANATELSRAISRVGGFDITVGAYPERHPES
PSIDHDIEVLKAKVDAGAMRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVSNFKG
LSRMSAACGASIPDWLAAHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNR
AELVYAICRVLGVRETRAVA
>A0A0Q6SJR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Root1212|TrEMBL
MAIHTLYPAERGNLRLSFEYFPPKNEEMETQLFDTVEALSVFSPSFVTVTYGAGGSTKAR
SLTTVCRMIKDTGLLNTAAHLTCVGADKADVDAVVNEFATCGVRHFVALRGDPQGGIGSR
YEPFAGGYENAAALVAGIRAKGDFEISVSAYPEKHPESADVATDIDMLKRKVDNGATRAL
TQFFFDNDDFERYLERVRRAGIAIPIVPGILPINNFGQMRKFAGLCGARVPDAIATRLEH
LDDQPVERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLIAAVCDLVGFERRPVVGHA
RHEGAAA
>A0A165FCL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenobacter luteus|TrEMBL
MSLPISIELYPGVLPAGDARVAELASRLAPLSPAFVSVTDGAGGISRAAGLALMDALAAQ
GYAVAPHLSAAGLDRESAAERLAEFAARGVKTLFALRGDTPSGMGERGDFRYASDLVRFV
REYWENAHGGRPELLVAAYPEVHPQAKNAHADLAALRAKQDAGATGAVTQYFYNVDAYRH
FVDAARAAGVTLPIVPGLLPLTRPSMARLAELRGVEMPRWMRRTLDACGGDAAALSDFGH
EVGVRLVTQLIDAGAPGVHVFAPGLAELAMAGRILADVGHAPQRAA
>A0A7W4B5C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas sp. SG44-4|TrEMBL
MALSLKEKIEDTNQGVYLIGTTPPKIDTDKAQLKIIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQARPFAFKQTVDPREYSHLLRNLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDL
QNVVLVGSPSSIGDIKLSLPDAYKAMAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGIIPQRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKQIA
>A0A847UWE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrionales bacterium|TrEMBL
MIENILSRIGRGVVVADGAMGSLLFERGLESGACYDALNLMDPALISSIHLEYVQAGAEL
IETNTFGANRIKLARFELGGRVREINARGAELARKSAGADRWVAGAMGPLGRLAEDMSDP
AELERIFAEQALALADGGVDVIMLETFASLSMLLVALRGVKSCVKVPVVAQMVFTQRGRT
HSGRTAQECFDALILAGADMVGFNCGIGPKNALDVVRELTPLAVPFSVLPNAGFPEAQGD
RLLYASSPEYFARQTAACVDQGASIVGGCCGTGPEHIAALVRVLGEGRGARLISVKPAEA
QDAQPISAEPTPLARRLSEGRVVLVELDPPKHLDVGPVLAAAEALQAAGADGITIAENPL
AVPRLSNIVLAGMVRQRTGAEVIVHLTGRDRNLVGMQSTIMGLAASGLYNVLAVTGDPPS
AGSAERVTGVYDVRSLELMGLLAGFNQGRNHYGDPMRLPVNFCIGGAFNPNTRNMALQVG
RMEKKIAAGAAYFLTQPVYSKTRVDEILSATSHIAAPIVLGVMPLASSRNAEFLHNEFPG
IEIPLEARERMARAGDQGQQEGIEIAWELLEYAWPHFAGVYIIPPFNRHAMALELMHRLD
R
>A0A2R4DGV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Concord|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7C4RIW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatirhabdium butyrativorans|TrEMBL
MHIPQAFKSGKFVVLAEMNTPKGVDISRFMTDARHIQGRVDAVVVPDMDNGVMRMSALAG
AAVLKQAGIDAFITTYGRDRNRLAIQGDLLAAQVLGVSGIVVVAAEPMANSDHRDAKPVN
DLDEIGILRCAAQLKQGKDLAGFDLDGSPQWIIGCTLPSVADDAALDREIESLRTKIQSG
ASFIVTPPVFDVDHFATIADKLKPLGVPIVAGVFLIKSVAVARYIATNEPGAHLPEATIH
RIRKASDREQECLQIAGETVARLKSVVSGVLIQTMGWEHRLPAVLDAAGLS
>N9TI45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 3880|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKTVHQELQQLNPEFFSITYGAGGSTRERTLAAISDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERITKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A2N8D2U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FW104-R4|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A2A4HH75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas nigrificans|TrEMBL
MSSQEHPLGISFEFFPPNTDAGRDKLIHVRDELAARNPRFFSVTYGAGGSTQARTRDTVR
SVSQSGINTAPHLSCIGSEKAQLRDLLAQYREEGVDSIVALRGDMPSGMASIGELRYANE
LVEFIRTETGDHFEIAVAAYPESHPQAPNLDRDVENFARKMQAGANMAITQYFFTADAYF
HFVEKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWVRKQLESYGDDSDSIAAF
GTDVITRLCERLLDGGAPGLHFYTLNQAAPVLKVVDNLVS
>I7HDY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter cinaedi CCUG 18818 = ATCC BAA-847|TrEMBL
MLDQLITKLKSNEPFLSVEVSPSLSSTIGQGVIDELESLSQADCFVCTDSPLARLKPSSI
LSSIKLQNALQKPVICTLSMRDRNSIALCGDILGANEFGLRSFLSLSGDGVKNGDCTGAK
GVFEESSLKLGRIIDGLNQGIAANGKVLKDSVETIYNFSVINSYANNTESLKKKMLKKLS
NSLVQGLFTQPVFSLESARFLLESMESINKELGQNCVMILGFFPVPSYKVALFLRDKLPG
VYIPDEWVQKLEKASIKGKEEERKIGLELSNKLFKDLQTLHNKFHFMSANKPSLLREFV
>A0A1M2Z1T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 65-79|TrEMBL
MTPSRPSSQRDENPAGVHLPLEPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVY
QRAAVFEGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVL
GAAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPP
AVFLGAAINPFAPPYDFRPMRLAKKIAAGAQFVQSQYCFDVPMFRTYMQRVRDLGLAEEC
FILAGVGPLASAKTARWIQSNVPGIHIPDAIIQRLEGAADQKKEGKQLCIDIINEVKEIP
GVAGIHVMAYRQEEYVAEIVAESGVLKGRQPWKREARQDDQIVADRLDRILHEDMTERPA
DRVARVRS
>A0A089JRC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL H7-0737|TrEMBL
MKPDLRSAWGNKVLVGDGAMGTYLYQKGFPVGISYEELNLTSPGVIEDVHRSYIDAGAVL
LESNTFSANFDRLSKYGLESKVEEINRAGVRIARKAAGDTGYVLGAVGSIRAGKRANLSS
TELKKYFTQQITALLEEEVDGIMLETFYDVEELHLALRTVRKHSTLPVICQFAVDESART
LDGLTLPEAFRILEGDGADIIGFNCNTGPNGIKRALKAVQGNLILPISVYPNAGVADYVD
GEYRYGASPEYFGQMAVTFAEMGCRIIGGCCGTTPQHIAEISSALKDYVPQPLPEPTLPT
VERVSLQEHFGEDEGRDGREPNLVDLVKERHTVIVELDPPRDLDIGKFMKGAEALRRAGA
DALTLADNSLAVTRMSNMALGHLVHAKTGLRPLVHIACRDRNLIGTQSHLMGFDALGIDH
VLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGISFSGKPLKQKANFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDQELIVKIAEATAHLDIPVFIGVMPLASGRN
AEFLHNEVPGIQLTDDVRNRMKGLEGEAGRAEGVAIAKELLDVATAHFNGIYLMTPFMFY
DMSTQLIEYVWEKSGRKLSPLFR
>A0A6A8MLS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosarchaeum sp|TrEMBL
MAVIYEINPPKIPDIKTSNEETNSLLSKLVQRVSDISTLCDGIHVTDSVLGTRRVSALTT
GKILKTNHPNLQITISMRVRDKDMDSIKQIVQESIDLKLDGILVLKGDPSKENPTDSGLI
PSHVVKQLNELGYGKKMNFFLSLPSNPDFEKIQKKITAAPKGFMTQVIHSTEQVQRISNK
LRPSGFRIIPCILLPTEKNENSAKFLELDWSGYKENPANFIKEIHSIAGDVLITSPNDFT
FAKETLKKI
>A0A1V4G8X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium mucoviscidosis|TrEMBL
MKADLRSVMQERVLIGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
HETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGANGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSNLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGASPEYFGQTAVQFADLGARIIGGCCGTTPDHISAIAKALVEYTPVPILEPDPSE
SKPRIILHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVSFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKMASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
SMTAELTQYVWEKSEHECPTCFNPNNQLQ
>A0A7Z1LGT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hodgkinia cicadicola|TrEMBL
MARLLNQTSVSFVAANSIYVRFSVEYLPPKMIPNLSEVLKSDLKSNRTKLLEFNSITRSP
KNKHALNSTTCCLSLLRQLCNCAVVLHNFLIQMKCMLIPNTSRPHGLGINNMLLISDDNH
TTNKKRSGDISSYKIRRLLRKKNVFNIGTDNPNNHILYSGSFQDLFTMLLNRESGCSMHI
TQIFDHMDNFLRNNLRCSIFKLGSLLPCLFISSKYPLAVDINLKCGIYLTRQVKELLESE
YLDERVAFLFNMYRIIEIIKNDITWIQVFTLNTTRILKEIIWILNDLTYYIRYWRLRTRN
ECYAVMCDMHNAYKKR
>A0A4Y9UXD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. MOS001|TrEMBL
MSGAMTDLTTPARAEGQDGHLQNGHLSSKRPAISFEFFPPKTEEMERNLWETINRLAPLD
PKFVSVTYGAGGSTRERTHSTITRILRETALLPAAHLTCVGASRGEIDEIVDRYHEVGVR
HIVGLRGDPAGGIGAPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDA
DIDTLKAKVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFV
TRAGTSVPDWLAEKFDGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVF
AISHLLGIRAKSAQKAA
>A0A1I5C6G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia ammonioxydans|TrEMBL
MTTTSVSTVTERISVDRPFFAVEFFPPKDDQGEADLWRAIRRLEVLDPAYVSVTYGAGGS
SRDRTVRTVERIATDTTLCSMAHLTAVSHSTDELRHVIGSLAAAGVRNIMALRGDPPGDP
LGEWVKHPEGLEYADELVSLIKRSGPFCVGVAAFPYGHPRSADLEADTERLIGKFRAGAE
FAVTQLFLEPDGFLRLRDRVAAAGFDQPVIPGIMPLTSEKTFHKGPELSGSPLPPDLVKR
LEPYTGDAKAFRAAGMEVTGELCERLIAEGVSGIHFYSLNRSTATTELVERLGLAVPRGT
ADRVESEAVLPV
>H5TJ81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia otitidis NBRC 100426|TrEMBL
MSQASPYTGPVNSSAPVPSVVERLSAPRPGPVPFSVEFLPPKDADAEARMWRAVRVFERL
DPAFVSLTYGAGGSTRDRTVRIAGQLATETTLVPVAHLTAVNHSIAELRSLVGAYADKGI
TNILALRGDPPGDPLGEWVKHPQGVSYAEELVELIGGLGQFHVGVASFPEGHHRAPDLDH
DTRVLVSKLRTGAEYSVTQLFFDVDFYLRLRDRVAAADPEQGAKPIIPEILPITSLASVR
RMVELSGSVLPASVEQRLIAAAGSGDQEDRAAVRAVGIDIATEMSQRLIAEGAPGLHFIS
LNFAKATCEVLDRLGVDTADALPLVSST
>A0A511DLR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sulfidoxydans NBRC 16205|TrEMBL
MTSTGTPDTRTALRGALQTLGYEVMPFARTHDAVREHVPTSIRLTVTASPQKGIDATVEL
ALALAADGYSVAPHLSARMISGPAQLDDILARLTANGVRRLFVVGGDGEASGTFTEALGL
LRAIRGSGHDFADIGIGGYPEGHALIPPERLSSALVEKAALADHITTQICFAPATLLAYS
RSLVEQGVTLPVVVGVPGAVSRQKLLRITASIGVGDSARFLRKQSSLFWRFFVPGGYNPT
SLVRGLRSELGGSSTVSGFHVFTFNDVESTERWRRRMLDRLDAVS
>R6U0V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:964|TrEMBL
MKVINKFKQNKTVFSLEVFPPKKFTDSIDIVYETLDKLTNINPDYISVTYSAGGGGNTEH
SCKIASIIKSTHHVEPVAHLTCLTNDKNDIDKAIADFKAVGVENILALRGDKNPDLTPKK
DFTYASDLVSYIKSKYPEMGVSGACYPEVHMESENEIQDILNLKKKVDAGAEFLISQLFF
DNSVFYKFVEKARIAGINVPIEAGIMPVTSSKQILRMVDMCGASLPRKFSMMMQKYGSNP
EAMRDAGIAYAVDQIVDLIANGVEGIHLYTMNNPYVATKIAENIKSLL
>A0A8B5ECL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. CH246|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAAGSINSQNTLEIASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLIKEELHA
>A0A3B9ST70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotomaculum sp|TrEMBL
MSILAKLLQQGEFVVTAEINPPKHACPENIKRQAKFIARYVDALNITDCSTAVVRLSSIA
AGFHILSCGVEPIIQMTCRDRNRIAM
>A0A316QN68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKDIRALLAQEAPLVFDGAAGTYFAARYGGSCELASLEQPEKVLQMHRAYLDAGCQAVKT
NTFALGAMYQEGGESLARKAILAGCMLAREAAAPYGAYVFGDLGPVAALEDADPAAIYLA
QAQLFLSQGITHFLLETLSSDQGVADFARQLKALCPSAFLLVSFGVQPDGYTREGLGGAQ
LFARMQACEGVDAAGFNCVCGPQHMLRQFQKLDPQGAVLSAMPNAGYPTVLGRRVVYRGQ
PDYFAQQGLALVRAGAKIIGGCCGTTPAHIAALVQAIRREKPVAVQAPAAPSPDPSPAPR
AAQSPLAPNPLWDKLEAGKRVVVVELDPPAQGSAQPFMEAAARLQAAGADGITVADCPIG
RPRADSSLLSCKLKRELGIEPLPHLACRDRNLSATRALLLGLSMEGIRNVLLVTGDPVAG
GQEDMVKGVFHFNARKLASYVAAMNDTVFPNPMRAYGALNVNAKNFQIQLKLAQEKEANG
ICAFLTQPVHSQEALENLKLARQTLHGKILGGVLPIVSYRNACFLNNEIAGVFVCEQILA
QYQDKDRAQGEALAVEISCAIGEAMAPYTDGLYLMTPFNRISLMETIMERLG
>A0A871RAS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dekkera bruxellensis|TrEMBL
MKVTQKLEGAHNDERSPASFSFEFFTPKTSQGVQNLYDRMDRMYNLNPLFIDITWNAGGR
LGTLTAEMVNVTTTVLGLETCMHLTCTNMGLEKIDAALDSAYKCGCENILALRGDPPLDG
SESTGVFRYAKDLIKHIKSKYGDHFCIGIAAYPEGHPEEHDISKTIKYLKEKQDAGGDFI
MTQMFYDVDIFIEWCKKCRASGITIPIIPGIMPISTYASFLRRAQWCEIHVPDHFLKRLE
PIKEDDSKVREEGVKLVAEMCRKLLESGYINHLHFYTMNLEKSTVMLLKQLGLVSKQQVV
GMDTKPWRRSLNPTRSDENVRPIFWQNRKFSYIQRTADWDEFPNGRWGDSRSPAFGSIEL
CDHELIRHSPKKALNLWGTPSTIGELSSLIIKYLQGKLSCLPWSDGKVTSEIDLIKDALI
DLNSRGVITINSQPSINCCPSADKVHGWGPKNGFVYQKQYLEFLVPTTSVNFITNKINET
NRDAGYSVLSYYSINSRGLLCSNVQSSSAINAVTWGCFPGEEITQPTIVEKISFIAWKDE
FFSILKKWISLFKKDHDVEGGKSIALIEMLIRDYTLMNIVDNDYVAEPNTRIFSVLKATF
PLKQ
>A0A0A1FBG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas arenae|TrEMBL
MSKLKQALNEGRFVYVLEVVPQQSPSRLAALEKIVQRGHLAGWPLLPAFADRVGLHSDLS
PLEGAGALADPASSLLHFSGKDRERADLLFQIESMKARGLEQLLLLSGDRLPGHHPDQAP
VHYLESVPALQIAREHCPDWLLGAALNPFKYREEEGGAQYLKAQKKLLAGADFFTLQLGF
DAAKHIEAQTWMRAQERMKPMLACVMNLTDKRAAVLQAVPGIVITESMRELLGREQQVSL
AYASARSLERLALQIVGLQLMGYAGAHVSGVHTLDELLSLEQAITEQQDNSITSLTDWVE
RWHASWRMPGAPQVCFAPETGAWEMGQSDVTATRRERLRYTLLSTVHGQLFSRTGWLSRA
FGWSVTRPIWKVGVAANALHAVERTVKRPLVGCDTCGRCRLQDTLYVCPETCPKGLANGP
CGGTRLNRCEFSDRECVHSVKYRIAKSANQLPVLAQTLIPCIEAGSRHRSSWPEWFEPED
STPGC
>D3AA79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi DSM 13479|TrEMBL
MRGPASLCIWIKRQGDRKMKTTDLFAKKPVLSFEVFPPKRTNPVETIYETLDSLRKLNPD
FISVTYGAGGSENCKATTEIASKIKNEYGIESVAHLPCIGLTKDDVISLLGGFKRAGIDN
ILALRGDIPEGGRPAGDFEHASDLISFIKEKEEFKDFNVVAACYPEGHTESENILTDIRS
LKTKVDAGADHLITQLFFDNDCFYRFKERALLAGIHVPVEAGIMPVTNKKQIERMVSLCG
VSLPSKFTAMMERYEHNPEAMRDAGIAYAVDQIVDLIARGVDGIHLYTMNNPYVASKIHE
AVYRLLAA
>A0A2U2C3Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararhodobacter marinus|TrEMBL
MAAPRISFEFFPPKTLDASFRLWETTRMLAPLRPDFVSVTYGAGGTTRQLTHEAVTTIGR
EFGLNVAAHLTCVDASRAETLAIADSYARAGVREIVALRGDPPKGQGRFSARADGFAHSL
ELISALKENGQFTLRVGAYPERHPEAGDDDADIAWLKRKFEAGADSAITQFFFEAETFLR
FRDKAEKAGIDAAKILPGIIPIENWEGIRRFAQATGAAVPAWMDEAFTKAARDGHEQLLA
TAICTELCDALMEEGVPALHFYTLNRAHMTRDVCYALGVTPQVALQKVA
>A0A356XFV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MDHTIAGTAVGIGGQKMEVISMFHTVQNKMYHVEILPPKQDTEQLEADLESFSKKYNRVI
NSGYCACITDNAMGLLGFQGSEIIDVMGLDVNPEKVVIHLNTFHTKEDLHNILDTCKSRG
IKYLLIISGDGSDRLPRLKPEDVNAMDVESVTSVELLKYIKDCCPDDFVLGVAFNPYEPP
NHEFEKMQRKIDAGASFIITQPIVEKNDRVDELLKKYPHIPVIVDAWMNKKLQILSEAVG
YKIPDDETFDPVVTLKKLHRDYPQCGFYLSLLSFKTQFDLLPGIWP
>A0A0Q9LGT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Soil522|TrEMBL
MRISLELVPRDEAELKAELQLMKAQFPEINTINIPDLLRFELRSWEASCMSKTLYESCIP
HIRAMDFDCAEPLPFIDRLDKHRITEVLVVTGDAPKNSGHRVYPTTCVDLIAKIKREHPH
IKVYSAIDPYRGSIREEYEYVQRKLEAGADGFFTQPFFDLRLIELYSEMLEGSDIFWGVS
PVVSGKSQKYWETRNHVVFPKDFQPTLDWNIAFSREALAFTKQTKSNIYFMPIKVDLAAY
FDGVFNKVSV
>A0A522ET85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea sp|TrEMBL
MTQRSFSFEFFPPKTAEGSDKLRATRMQLAPLKPRFVSVTFGAGGSTQQGTLDTVVEIQR
EGTEAAPHLSCVGSSREGIRAILDTYRNHGIRHIVALRGDMPSGMGEIGEFRFASELVEF
IRAETGDWFHIEVAGYPEYHPQARSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DTRKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWIAKRLESFGDDRDAIRAFGLDV
VTALCERLLAADAPGLHFYTLNGAAATKAIWQRLGLS
>A0A2V2D4N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKLNHLFDTKQVLSFEVFPPKRTAPVESIYDALDSLKDLHPDFISVTYGAGGSENCAATL
EIASSIKNKYGIESVAHLPCINLSKEDVLGMLQSFRENGIENILALRGDRNPDVPPGKDF
QHASDLITFIREHGDFHIIGACYPEGHTESDSLVSDIRNLRRKIDAGCEHLITQLFFDNE
YFYRFRERCLLAGIDVPIEAGIMPVLNKKQIERMVTLCGVCLPAKFTKMMERYEHNPEAM
RDAGIAYAVDQIVDLIAQGVQGIHLYTMNRPDTARRIHDSIAALLA
>A0A149VSF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrovum sp. PN-J185|TrEMBL
MDSQKGHPKLFSFEFFPPKTPEGMEKLRQTQRQLSQLHPAFFSVTFGAGGSTRERTLGTV
LDILKEGDQAAPHISCIGTTKDTLKDILEQYLANGIRHVVALRGDLPSGTYGGGEFRYAS
ELVHFIRQEVSKELIIEVAAYPETHPQARSAQEDLLHFKEKVEAGANAAITQYFYNPDAY
FDFVERCEQHQITIPIVPGIMPIANFSQLSRFSDACGAEIPRWIRQKMAGYGDDAASIRA
FGLDVVTHLCDTLLSAGAPGLHFYTMNSAGLTSVIWDRLHLSSYKT
>A0A365TK17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sulfidaeris|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTREVVR
AVSESGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAANLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVKQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLEGGAPGLHFYTLNQAAPVLKIVDNLTD
>A0A316RRM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKIKAILEQKPTVSFEVFPPKQWDKIEGTKAVVKEMVKSHPAFMSVTYGAAGTTSGFTTE
IAREILDDGVTPLAHLTCLTSTRDKIHQVVAELQENCIENILALRGDIPRDFQFPAEQYF
EHAYQLVNEIRTLGDFCIGGACYPEVHPESKNRVEDLEHLKQKVDCGVDFLTTQMFFDNT
VFYNFREMCAIKGIDVPLIAGIMPITKASQLERTVKLSGCSLPTKFVKIVERFGDRDDAM
QQAGIVYAAEQIIDLMANGVDHIHIYTMNKPDVAGAIVRELGSIIHE
>A0A2S4ZGK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ru62|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVLPVTSVKMLERLPKLSNAHV
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A2J8USL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pongo abelii|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKANHSGW
>A0A7X1HC95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. AQ_MP|TrEMBL
MAQIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKVF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDQSKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDHVIKRLEGAEDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGILKGRKPWKREHARADDIAAERMREIGADPVQDQQELAARAA
HAQQH
>A0A7C1MUG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPQDIIKTFSLEYFPARTEKGEQSLATTRKELSKLKPAFASVTFGAGGSTQDGTYQTVKT
IIEEDGLEAAPHISCISTNRNTLAKMLAEYRKLGVKRLVALRGDIPSGYGTAEHNELRYA
NELVEFIRRLTGDYFTIEVAAYPEFHPQATSAQADLINFKRKVDAGADSAITQYFFNPDA
YFRFIDDCQKMGLKIPVIPGIMPITNYKQLARFSDACGAEIPRWIRKRLESYGDDLESIR
EFGLDVVIRLCEQLLEGGAPGLHFYSMNRNEPVQTIWNHLKLSG
>A0A857MMN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus stearothermophilus|TrEMBL
MGLLDVLKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIIHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALIRLEEIGADVVGLNCRLGPYHMLRSLEEVPLLKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEEAAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIVKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDVSSFDLIRLISQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPVYSEEKIVQIYEATKHLATPIYIGIMPLVSARNAEFLHHEVPGIT
LSDEIRARMAACGSDPVEAAREGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A7X2N1H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Floccifex porci|TrEMBL
MNVKEYLKENRLLFDGSMGTYFTSLHPYCKENVELVSLTHPNWIKEIHENYIKAGSNAIK
TNTFCCNRTYISDETVLSDCISTSYDLASQYPAYVFCDIGPVSSEWKSYEEYKWVVDQFL
NKGAQYFLFETLSNPIGLNEISSYIKSKNKEAYIICSFSIQSDGYTKEGIHIQDIISSLN
KDKIDAIGLNCGCGVHHMHEILKEIGSFIQFISPNAGYPTVVNNRTQYQLDPDYFATEMI
SMMQKGIKMAGGCCGIMPSHIQALYNKIKQTSLIQSDFKNKKNIVKNSELSESDFFKKLK
NHQKVIAVELDPPSNWDLSKFMKGAWQLKEYVDALTIADCPIGRARMDASLLACKVKQEC
KLDVLPHMTCRDRNLNATKALLLADYAQGIRDVLLITGDPIPSSEKDEVKTVYQHNSRKL
ASYITSLEQKGLMSHFNLFGALNINAVNFDIQLKLAKEKIQNGMVGLFTQPVLSKEALYN
LKRAKEELDVYIMGGIIPVVSYRNAIFMENEINGIHVCDQIIDLYKDLDRMQSETQAIKI
SGTIMKEIEDYVDGFYLMTPFGRSELMVKIIDFYKQL
>A0A2J8USN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pongo abelii|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQL
>A0A7C6T7C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSNQPRISFEFFPTKTDAGHEKLITTATKLATYNPEFFSCTYGAGGSTRDRTLNTVLQLD
SEIKVPTAPHLSCVGDSKEDLRELLHLYRDAGIKRIVALRGDLPSGMGMANGELRYANEL
VEFIREETGDHFYIEVAAYPEMHPQARDFEVDLQNFARKVQAGSDSAITQYFFNADCYFY
FVERTRKLGIDIPIVPGIMPITNYSKLARFSDSCGAELPRWIRKQLEAYGDDIASIQAFG
EEVITNMCERLLEGGAPGLHFYTLNQAEPSLAVWDNLQLNR
>A0A6L7JPI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGKLKQRIDAGEFIVTCELTPPKGIDLKPLLDKADSLKNHVHAFNLTESHAARMAMDPTA
VAHLLLDRGVEPIVQMTSRDKNRIAIQACMLGAAALGVENLVFMGGDPPKNGDHPDAKPV
FDLFASQLLDAVNALQSGTDYTGNKLNGTPSFCVGAVFNPGSTNPDVEIENLHRKIEAGA
SFLQTQAVYDVEEFTRFLDKCGEIKVPVLAGVIPIKSVKMAMYMNERVPGITVPDHLIQK
IADHQENKEKIVETSQQISADIVRDLRQAAGGLHMMAIGWEDKIPGIMELAGV
>A0A7W7WI07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora gansuensis|TrEMBL
MPHHEAPQLGAPAGEPTYSFEFFPPRTELAERRFWNALRRVEAVGPAFVSITYGAGGSSR
EKTVRIAERIATETTLTPVAHLTAVGHSRAELRNIIGQYADAGITDVLALRGDPPGDPRG
VWRKHPEGFRHAVELVELVRATGRFRIGVAAFPEGHPRSPDPESDLRHFVDKCRAGADYA
ITQMFFQAEDYLRLRDRVAAAGCETPIIPEIIPITDHGQLARFAELSGATIPAELADRLE
RCRDDAAEVRRIGLAHAVEMSTRLVAEGAPGLHFITLNRADDALEIHRAVRRTATDHRSA
GNWGAASRRRGTHLAGFSSVADAPHGLPPRRRRGTHPTAAPSPTPQLSADLNPMSA
>A0A6L8FBY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSRPPKISLEFFPPRTEELIAMLEASLRRLLPYGPLYCTVSYGAGGSTREGTARWVRRIR
QDFGIDCAPHLTHVSHTRDEVREIVRGYVAQGVRRMIALRGDIPADGIPDKVRKRGYSST
VELIADLRVEGINEVMVGTHPEHGGGDSASLRRHLEFVKQKLDAGATLAITQFFLDNHRY
YRLRDVFAGAGMEHLLAPGIMPLHNYRQVFSFAGKTHVEVPSALRDRFQRAGENPDAVRQ
VAEGFSLDQVRDLADNGVERFHIYTMNRAPLTAAICETLGLSAPGTQS
>A0A7L3TPQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Uria aalge|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVAGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A661FU82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSNAEKNERETQVSFEFFPPNTEAMEKTLWSSIERLAVLQPRFVSVTYGADGSTRQRTHA
AVERIMKETNLTAAPHLTCIGASKGEIDDIAREYWDMGIRHLVALRGDPPKDVTTYVPQA
DGYAFASDLVAGLKQVADFDISVAAYPDVHPEAASAEADLENLKRKLDAGASRAITQFFF
DVGGYLKFRDRCASAGIDSTIVPGILPITKFPQLQRFAEACGLKVPQWLADRFAGLEDDP
ETRKLIAANVAIEQVRMMQKEGIDEFHFYTLNRADLTFAICHVLGVRPEQAAA
>A0A2A2B319|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. JB193|TrEMBL
MSKPAFSFEFFPAKTDQGREKLLSTFDELNTLSPTYFSVTYGAGGSTRSRTLDIVQALST
RGDTDIAPHMSCIGDDKSEIAELLEHYKSLGINRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDRFRIEVAAYPEMHPQARSFEFDVDNLVNKFQAGANAAITQFFYNADSYLYLR
DTLEKRGINTIDQPLVAGIMPITNSSNLIRFADSCGADIPRYVRKQLFDYGDDSKAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVEALGLTA
>A0A2E8I2E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionaceae bacterium|TrEMBL
MKIIDKINQSIVENKPFFSLEFFPPKTKAGIQNLYDRLERMARLEPAFVDFTWGAGGSTS
QLTLELCQSAQKYFALEVMMHLTCTNISEAEIRSALNSARDAGIKNILALRGDPPVGSER
WVKRDDGFAFGADLTGFIRTEFDDWFGVGVAGYPGGHPESASLESDI
>A0A661H4F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSKPRISFEYFPPKTEAGRDKLLGETTPALNALNPEFFSVTYGAGGSTRDATLGVVSAIR
EAGIDVAPHLSFGGDDEAAINALLDAYRERGIRRLVALRGDMPSGMGGARQLVYANELVE
FIRKCSGDHFEIEVAAYPEIHPESKSYDEDIRFLKQKLDAGANSAITQYFYNVESYFYYL
DQCAAAGIDKPIYAGIMPITNYQNLARFSRNCGAEIPRWICQRIEGYGDDQASIRRFSVE
IITQLCQTLLDSGAPGIHFYTMNQVEPTREICNNLNL
>A0A413DX46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF05-8-2|TrEMBL
MRVDEVFEQAASLGTTPISFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
GDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A661FZX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MLSTKKTLSKAEHNTLLHTVREAYMEVFPTSSIESRLDVLEPGSYVAVTCSPSKGVEVTL
DMVERLAQRGFKVVPHVAARMVRDDAHLREILQRLDDLPIISLFVPGGDAAKPIGKFSCA
LDLLRAISEFDHKLSEIGVASHPEGHPSISRDVLMKDLLKKQEFSNYLVTQMCFDARVLG
GWLREIRDLGVTLPAWIGLPGVADRSTLVKTSLRIGVGDSLRYLKNRGKIAANLLKSKSY
RPDELLADLAPYIADPSYNIAGHHIYCFNQVESAEQWRHEFLDALQSQD
>A0A1M7P7S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. OK098|TrEMBL
MKITEHIQNAKGKTLFSFELIPPLKGHSIQGIYDAIDPLMEFKPPFIDVTSLREDFIYKQ
HENGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLQFLGIEN
VLVLRGDARLGDASFVPNPNGHCYATDLLKQVVNMNNGVYLHENLGENLKTDFCIGVAGY
PEKHFEAPNLKSDFKYLKQKVDMGAGFIVTQMFFDNQKYFDFVNNCRANGINVPIIPGLK
PITTSKQLVNLSKTFHIDMPDDLCDLIHGCKSEKDVKEAGIEWMINQCKELMAFGVPVLH
FYTMSNAGPTKKIAEAIF
>A0A3S4JDJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella aerogenes|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A660L0T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacter pauli|TrEMBL
MTRIDEQLGTEPIVSFEFGPPRSVEAELAFWTAIEELAALEPAFVSVTCGAGGSTRDLTL
AVVRRLAHERGLEAVPHVTATGFTRDELVALLAEAAAGGADNVLALRGDPPRGETTWRAP
EGGVKSSLELTELAAAAGLCVLGAAYPEPHADSRGWADDLAHVRAKVDAGVRVLVTQLFF
DNDDYRRYVDGLRAGGVDVPVLPGIIPITSIGQVERITALCGATIPPALRRELETRQDDP
RAVAELGVAYATAQAAELLGEGAPGVHLYTLNRSPATRAIVSALRAAGVLPAATRAA
>A0A2E5M895|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAKTEQSRSTARLSFEFFPPRSEKGHASLQRVATKLSELRPDFYSCTYGAGGSTKSGTRD
TVTRLVQQGLSVAPHLSIGGDPRQEAFALLDYYRDLGVDRIVALRGDLPSGIGLNRFGHN
AETLVRWIREHSADHFHLEVAAYPETHPDATSPAADLEFFKRKVAAGANTAITQYFYNPH
AYFDFMERCGKAAIDIPIYPGVMPITNYEGIIRFSDNCGADVPRWIRKQLEAYQDDEKSL
KQFGVDVVTALCDELLDAGAPGLHFYTLNRWGASVAICANLGLNQRAA
>G7SHK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis D12|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A3C0EW98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MELNPKPIFSIELYPPRTTPDESKLDEVHDQLASLEPDFFSVTYGAGGSTKQGTKNIILK
YQQLGSNMVPHLSLGGTDRDDIRILLTAYKAAGINHLVALRGDLPPNTTTPVQHQYASEL
VEFIRLETGNHFHIDVACYPEPHPDSTSYKSDIAYFKKKIDAGANSAITQYFYNADAYFY
FVDYCSKAGISIPIVPGIMPINNYTNLKRFSAKCGAEIPHWLQKRLEGFEGDVEGLKEFG
IEVVTTLCERLLAGGAPGLHFYSMNLAKSVNQIWKNLALSDRS
>A0A3A2ZV87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus sclerotialis|TrEMBL
MHIKDKLSQQEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHSLGPAFIDVTWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPRERVDDALQAAFKAGCTNILALRGDPPREKES
WEVTPGGFRYAKDLVKYIREKYGNHFDIGVAGYPEGLDDNRDVDLLIDHLKEKVDAGGSF
VITQMFYDTDNFAVWVKKCRDKGITVPLIPGIMPIQTYAAFIRRTNWTKTRIPPDWLELL
EPVKNDDAAVRDIGKKLIADMCRRLFAIGINHLHFYTMNLAQATRLVLEDLKLTPSEETP
LQRPLPWRPSLALNRRGEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSLKDLTELFIRFLEGDLERLPWSDTPITAEAKAIKPNLIN
LNKRGFLTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLVPPYLYDELMARIEKNE
DLTYHAVNKAGELKTNTRDSPNALTWGIFAGREIIQPTIVETISFLAWKDEAYYLGEEWA
KCHDASSPSRKLIQGLMDDWYLVNIVNNDFHNTHDLFQLFEDLTVKDLDVEVPADTASKP
VVNGSSGTNGVTPHQNGTPAEIAAKN
>A0A7X1SCM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISNEPMKDDFRFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>A0A673IBF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus rhinocerous|TrEMBL
MGSCCVKFCGVICWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAET
FLRFVKNCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIR
SYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKE
ALLQMWGEELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVN
RRGILTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPR
VNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQW
AKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFALLDSPRETQEEGSQ
S
>A0A7C3HL39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacterales bacterium|TrEMBL
MNELKTGRICRAAEFRDLISRRAVVADGAMGTMLYGRGVFINRCFDELNLSMPQLVRDVH
LEYVRAGAEIIESNTYGASRPRLATFGYGNQVAQINRAGVRLAREAARERSDVFVAGAIG
PLGIHIEPLGPTSFSEAREAFAEQIQALCEEGVDLLIFETFSHLPELREALEAGRQIAGP
EMILVAQVTIDDEGHLHDGTRLETYGPWLESCPADVVGINCSVGPKATLETLEKLMRFTS
KTTSAMPNAGHPTKVEGRNIYLSSPEYMAQYARRMLWAGVKLIGGCCGTTPEHIKSIKSE
ARSLQPGTQRLQVTVEEPQAKSKKMEKVPVAEKSELGAKIAAGKFVAFVEILPPRGVNPE
KEIAGAALCKQHGIDVINVPDGPRASARMSAQVTCQLIQKEAGIETVLHFCCRDRNILGI
QSELLGAHAAGVKNLICITGDPPRMGSYPDATAVFDVDAIGLANIVNNLNHGLDIGGNPI
GSQTALLLGVGANPGALNLEEEIRRTAWKVEAGAEYIVTQPVFDIEQLKEFLRRIAGFRI
PVIAGIWPLTSYRNAEFMVNELRVPVPEKFMERMKRADDPEKARAEGVRIAQEMVREVRP
LVEGVQLSAPFGRYQMAVEVAEAIGPR
>R5SAI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:122|TrEMBL
MNFKDYIKTHNILADGSFGTYYAEKYHTNEAPEYANIYHKDRVTNIHSSYLDAGANLIRT
NTFATNTMSMQKDFSFVEDNIKEAVSLAKIAVKLSGKKDIFIAGDIGPVSTVSGVSDENL
INEYFNIAKTFADEGIEIIQFETFMSLDVLADVIPKIKKELGLFIMVSFSVNQLGYSASG
LSAKNLINDICAVDGVDAVGLNCGIGPYHMYNILEKIKLPKDKVLIAIPNAGYPVLTRNR
MEFNSHPEYFAEKTKELLSLGADIIGGCCGTSPEFIKSLYDIMSMDIKADKKIRKADSAD
EKVSKKCGFLYDENGRKKDKKFIAVELIPPFNTDDEKLLESAHYLKNAGVDVLTFPDSPS
GRTRVDSVLMAAKVYRETGIEVMPHVCCRDKNAFAMRAMFMGAKINDIKNFLIITGDPVP
ASARDLVKSVFNFSSVGLMKIAQEMNREVFNENPLNYGGAINQNLINLESIINTTKRKMD
AGASFFLTQPVFSKEEADRLREIKEETGACIFAGIMPLISRRNALFMKNEIAGINVTDEI
VNRYPENGSKEDGEKVAVELAKEIISYIDDFADGYYFSFPFNRVYLLNRILG
>A0A2N5LKH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. MES7-P7E|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALST
RGTTEIAPHMSCIGDDKSEIAELLEYYKTLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
YIREYSGDHFHIEVASYPEMHPQARSFEFDIDNLVNKYQAGANASITQFFYNADSYLYLR
DKLEKRGIDTVAQPLVAGIMPITNSSNLLRFADSCGADIPRYVRKQLTDFGDDRKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLTA
>A0A328RIT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinamargulisbacteria bacterium SCGC AG-343-D04|TrEMBL
MIFLELVPRDLNTLISDSKQYLAQYTAITGINIPDIKRLENRSFTAVEKMLENDITAMPH
IRTQDFSLDEHLKIVSALYDKGLRHILLVSGDPSNDPLQKTYKVTPMELTKELKKVFREL
KVYCGIDPYRQTMQREVAYALQKLEAGADGLFTQPFFDLNLAEGYLKQLSVTQLFMGVSP
VITEKNKSYWVNVNHVVFPEVFEYTLHYNATFAKELIQLTQSYKQHNYLMPIKIDIQDYL
DQVFR
>A0A0J8SQJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. VT 511|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADNFDADIKRFCEKAHAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A0J9XG79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geotrichum candidum|TrEMBL
MKISQKLQDAHKTSESSPTYSFEFFVPKTSQGVQNLYDRMDRMYDLGPAFIDVTWNAGGR
LSNLTCEIVSTSQSILGLETCMHLTCTGMPKELVENALKDAYKSGCQNILALRGDAPHAS
DKWSSVEGGFSYAKDLIKYIRDTYDDYFDIGVAGYPEGHPEEEDIDQLIVYLKEKVDAGA
TFIITQMFYDVDNFINWVHKCRAAGITVPIIPGIMPISTYDSFMRRAKWCEINVPPAFLA
KLEAVKHDDVQVREVGTQLVADMCTKIVDAGVKHLHFYTMNLEKATIMVLERLNLLSPLE
ERSSINAPALPWRQSLGLTRKEESVRPIFWKNRKHSYVTRTQDWDEFPNGRWGDSRSPAY
GALETYGVLLRQSKTKAIDLWGEPTTPAELGALIANYLGGKVKSLPWSDTPVSAEIDEIK
SNLVTLNQRGIFTINSQPAVNGIKSSDPIHGWGPKNGYVYQKAYLEVLVAPELAGSIIER
IAADPEITYYSVNNDGDLTTNAPLGGGPNAVTWGIYPGKEIIQPTIVEKISFLAWKDEAF
RLAYDWSCCFDEGSPARNFVEEISKKWYLINIVHNDFQSKDGIFKVLEGIEGLN
>A0A401RDS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albulus|TrEMBL
MFFHVEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAQLSHAAFPEELAHRLEAAR
DSPADGHRIGVDHATRMALRLLDEGAPGLHYITLNRSSAPLDIHGHVCRSRSLHAC
>A0A2N0EQN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ulvibacter sp. MAR_2010_11|TrEMBL
MKVLEHIQNGNGKTQFSFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYVYKE
LENGFLEKKVVRKRPGTVGICAAIQNRYEVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKTETYFTPEKKGHAYAEELVKQIRSLNNGEYLDAEILNQAQTNFCIGVAGY
PEKHMEAPNMESDIHFLKKKITNGASYIVTQMFFDNEKFFSFVQKCRDAGITVPIIPGLK
PLASKKQLNLIPQRFNANLPETLIKEVLKCNNNDDVRQVGIDWCTAQSKELMQHDIPFLH
YYSMGKSDNIKAIASQLF
>A0A379A9C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter agglomerans|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSDMEETLWTSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGISAGL
>A0A2G5EVM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquilegia coerulea|TrEMBL
MKVIEKIREAEAENRVVFSFEFFPPKTDDGVDNLFDRMDRMVQHNPSFCDITWGAGGTTA
DLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQDK
FVQIEGGFACALDLVKHMRGKYGDYFGITVAGYPEAHPEVIDSSGVATLEAYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPIGNYKGFMRMIGFCKTR
IPAELTAALEPIKDNEEAVKKFGIDFGTEMCKKILAHGIKQLHLYTLNMDKSALAILQNL
GLIDEAKISRPLPWRRPTNIYRVKEDVRPIFWANRPKSYLTRTIGWDQYPHGRWSDSGNP
SYGALTDYQFMRPRSRDKKLQEEWAVPLKSVEDIHEV
>A0A4Y8HQ81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. URIL14HWK12:I1|TrEMBL
MPACQHPVSVMSVLKTALQEQQFACVMEFVPKPSAERFAAMDAIMARGQVCGWPMTLAIG
DRVSSPLDMSPLDALACFEHPVPALPHFSGKDRERHHLLAQMRRMDAAGQHQLLMLMLTG
DRLPGHTPGERPVRYLESVAALQIARQAYPHWWLGAALNPFKYREEEGAAQYLKAEKKLA
AGADFFILQLGFDAAKHQEAMHWMRRQRAPKPLLACLMSLTQGRAGMLDHVAGVTVTPSM
RQMLEAETAQSKAFAQARSIDRLALQVIGVKLMGYAGVHLSGIHEPSQLLALEARLEHWQ
AHVTTLEQWAPAWQASWQMPGLPAVTFHPPQAAWREGESRVVATFAQKARYHAMHGMHGL
LFSRSNPVSQLFGWAVRQPMWTTGLGAQVLHILERAVKRPLLGCDTCGRCRLEDTLYTCP
ETCPKGLANGPCGGTTLNRCEFGDRECIHSAKYRTAKAVRQTDVLAQRLIPCVEQHTRHR
SSWPGWFGAQAQPVTRPSAPRSRPES
>A0A366K3S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus firmus|TrEMBL
MSFLKKLKNEIIIADGAMGTLLYSYGTDSCFEELNLSQSEQIQHIHEAYIGAGAELIQTN
TYAANYLKLQRYGLEDSVKEINSAAARIAKKAAKGRAYVAGTIGGIRGFKPNMITLEEIK
RSFREQLYCLLLENVDGILLETYYDLEELETVLAIARKETDLPIIAQVSLQEAGVLQNQT
SIGDALTRLEGIGADVVGLNCRLGPHHMLKTLESVPLPKHAYLSAYPNASIPAYTDGKFH
YEGDAEYFRQSAIEFRNQGVRLLGGCCGTTPDHIKAFSDELKGLAPIEEKETRAINKVIV
SEKPSSSRELPPLHDIVRERPSVIVELDPPRKLDTSRFFEGAKALKEAGIDSITLADNSL
ASPRVCNSALGYLVKQQTGLRPLVHVTCRDRNIIGLQSHLMGLHALGLNDILAVTGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSFSGKDLGQKAAFSVAGAFNPNVRSLEKAVG
RLEKKIEHGADYFISQPVFSEEKLLEVHEAVKDLKAPVYIGLMPLTGSRNAEFLHNEVPG
IKISDSIRNRMASLKDDPAQAGAEGIAIAKSLIDAAAELFNGIYLITPFMRYEMTVELSN
YARETTERLSRRKQHA
>A0A7Z1INL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter vinifirmus|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRAEIGELLDVYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGITIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEDVITEMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISDREKIAF
>A0A2J8KXA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pan troglodytes|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYE
EESPSRSIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELVNRPTQNARETEAP
>A0A2G8MU38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 382|TrEMBL
MSLLKAALREKHFVCVMEFVPKPSAERFAAMEAIMARGQLCGWPMTVAIGDRVGSPLDMS
PLDALPSFNTPLPALPHFSGKDRERHHLLAQLQRMDAAGLNQLLLLTGDRLPGHQPGERP
VRYLESVAALLIARQACPNWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DASKHQEAIHWMQRQASPKPMLACLMSLTHGRATMLEHVAGVTVSPSMRDLLEAESKVSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGIHELKQLLALEERLEHWQAQIHSLEHWAPA
WADSWQMPGLPIVAFHPPQGNWRQGESTVSASGKEKVRYHLLHSAHSLLFSRSHWLSKAF
GWAVRQPLWATKRGARVLHGLERAVKRPLIGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFEAQPP
RQLSPQPAPRTQPES
>A0A7C4ESV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomonile tiedjei|TrEMBL
MSTECVTDSRLEKILRAGHFAVTGECGPPRGADPEAVRKKCRILKDKADAFNITDNQTSV
VRMSSIASSVIMMQEGMEPVMQMVCRDRNRIAMQSDILGGAALGIKNMLCLSGDHQRFGD
HPQAKNVFDLDSIQLIRMVRKMRDESRFLGGEEIKTAPKLFIGAAANPFADPFEIRVPRL
AKKVAAGVEFIQTQCIFNIKKFAEWMKQVVDRGLHEKVFILGGVTPFKSFGMARYMANNV
PGMDVPDELLQRMKGTPKESQAEEGIKIAVETIQQLREMKGIAGVHIMAIEWEEKVGEIA
ERAGLLPRPAV
>A0A355BSK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagales bacterium|TrEMBL
MKVTEHIKRANGKTLFSIEILPPLKGENIRTLFDNLDPLMEFKPPFIDVTYHREEYVYKK
KENGLLEKISTRKRPGTVGICAAIQNNYKVDTVPHIICGGFSREETENALIDLQFLGIDN
VLALQGDAIKTEARFVPDPHGHKYASELLEQIVAMNKGRFLDEDIHASPTNFCIGVAGYP
EKHFSSPNLKSDLKFLKMKVDMGAEYIVTQMFFDNQKYFDFVARCRETGITVPIIPGIKP
ITAKVQATVLPTIFHIDLPEELADEVEKCKDAAAVKQVGIEWCVKQSRELMKFGVPTLHY
YSMGKSDPIYRIAKELF
>B3TCN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured marine bacterium HF4000_APKG2098|TrEMBL
MEYQSPLHKKLHDGVFVFTAETTPPDSSNKETLLKKIKSLKDVADAINVTDSPGAKVHMS
ALTAAIILAQNDIDPILQLTVRDRNRLALQGDLVGASALGVHNILCLSGDDPKVGDQPET
KPAQDIDSTTLVATANMMRKDKKFPSGRAIDPAPKLFIGGAEVPSKGKPNTEKILGKIKN
GIDFFQTQYVFEAKKLEEYMKVLNDAGILEKTSFLIGLGPFASAKSAKWMNDNLFGVDVP
DEIIKRLEQAKDQREESKKVCLELIQIFHEIKGVKGIHLMGHKKEEVIAEIIKESKIS
>A0A1A0GHB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGEHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDCESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A1Q3U7C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium 39-19|TrEMBL
MKITDHIEQAKGTLISFEILPPLKGKGIQSLYQQLDLLMEHKPAYINVTYHRSEHVFKKT
ADGNFQKVVVRKRPGTESICASIMNKYNVDTVPHLICGGFDINETEDALINLNYLGIDNV
LVLRGDAAKNEANFDPEPGGHRYAIDLLKQVVNLNAGLYLEEDLKNTSKTKFCIGVAGYP
EKHFEAPNMESDLQYLKQKIDAGADYIVTQMFFDNEKYFSFVKACRDLGITVPIIPGLKP
IYSIKQLTILPKIFHIDLPTALSNEISKCKTDLEVEEIGEAWLLAQSQELKKAGVPVLHY
YTLGRPHMVSRVVSKL
>A0A4S0YRD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.163.01.1.1|TrEMBL
MNQFRFSRRPDIGEKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVIREFVDFGVTRFVALRGDPAAGVGT
IYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLGNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
AGSAAA
>A0A1G7C5W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ulvibacter litoralis|TrEMBL
MKVTEHIEQSQGETLFSFEILPPLKGQNIQSIFDGIDPLMEFNPPFIDVTYHREEYVYEE
MANGLLQKKVVRKRPGTVGICAAIQNKYNVDAIPHILCGGFTKEDTENFLIDLGFLGIDN
VMALRGDAVKSETYFTPEKEGHSYASELVSQITSLNKGCYLDPALQNSTPTDFCIGVAGY
PEKHMEAPNMDSDIHFLKKKIKNGATYVVTQMFFDNEKYFNFVSKCRKEGITVPIIPGLK
PLSTKKQLNVIPHRFNADLPEALIKEVLKCTTNAAVREVGIEWCTQQSKELLEKQIPVLH
YYSMGKSDNIKSIVKELF
>A0A0M9WMY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus rhodochrous KG-21|TrEMBL
MDRLRAPRGARIPFSVEFSPPRDADAEARLWRAVREFERLGPAFVSMTYGAGGSTRDRTV
RVTGELAEETTLLPVAHLTAVGHSVDELRAMVGAYADRGITNILALRGDPPGNPLGEWTR
HPQGLEYAEELVRLVRDLGDFHVGVASFPEAHHRSPDLEHDTRYLVHKLRAGAEYSITQM
FFDVEDYLRLRDRVVAYDPEQGAKPIIPEIMPITSLRTARRSLELSGSKLPATLEERLVR
AAGNGPEEDRAAVREVGIDVATEMAERLIAEGAPCLHFITLNFARATREVLARLGIAVPT
AV
>A0A538U2V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium|TrEMBL
MPSTLLDRLARGPLLADGAMGTLLNQRGISFEHCFDELNLSRAGLVEGVHRDYLAAGAEL
IETNTFGANALRLATHGLDEKVRLIARQGVKIARAAREIVGVEAFVAGSMGPLGKVLEPL
GPVTTSEAEAAFQAAAEGLLEGGCDCFVLETFQDLGEALAALRAVRRVSMDLPVIAQMTF
GTDGKTMYGHTPTEAVRAFREHGASVVGINCGVGPQPILELVEEMIRAAGDMPVSAMPNA
GLPQYIGGRFVYLASPEYFAEFAARAVDLGVRLVGGCCGTTPLHIRAMRERLASRLPAEK
LAPGAEVRVLEQAPVTPESPGPRETPALLRKLGETFVVSVEIDPPRGINTAKVMEGARLM
ASRGVDCVNIADSPMARIRMSAMALAYQIHTHFPRLEIILRFTCRDRNLMGLQSDLLGAH
ALGLRNILALTGDPPSLGDYPNATAVFDTDAPGLMRIIHRMNQGSDLAGTSIGAATQFAV
GCGVNPTADDLDAEIEYVKRKLEAEPHFIMTQPVYELDCWKRFVDHLRGISQVPILIGIL
PLQSFRHAEFLHNEVPGITVPDWIRQRMHEAGNEGQRVGVDLAKELLARCKGMANGVYLM
PSFGRFENCLETLEGAR
>A0A849SI25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium|TrEMBL
MASPFLERLARGPILADGAMGTVLYGRGVGFEHSFDLLNLDRADVVESVHREYLSAGAEL
IETNTFGANAVRLAPHERDRDVHRIARQGVKIARAAREIVGLPAFVAGAIGPLGKPLEPF
GHITVEDAQRHFRVTANGLLEGGCDVFILETFQDLDEILAALRAVRAATTELPVIAQMTF
GTDGKTLYGHTPAEAVAALKNAGASVVGVNCGVGPQPTLEILEQLVKAAGDTPVSAMPNA
GLPRYVDGRFLYLASPDYFAEFAARAIALGARIVGGCCGTTPAHVAAMRARLANDAPLES
LAPGAEVTVLEAPPAPVQPTQSSEVPSFLLKLRDKFVVSVEIDPPRGINTQKVLEGARLM
AAHGVDCINIADSPMARIRMSAMALSFQIHSRHPELEIILHFTARDRNLMGLQSDLLGAH
SLGLRNILCLTGDPPSLGDYPNATAVFDTDAVGLMRMVQRMNQGTDLAGTSIGAATRFAF
GCGVNPTADDLDAEFEWVKKKLEAGPQFLMTQPVYELDCWKRFIERLGGITDVPVLIGIL
PLQSYRHAEFLHNEVPGIVVPDWVRARMHDAGNEGQKVGLELARDLLTQCRTLANGVYLM
PSFGRYENCLAVLEGLS
>A0A7K3DZA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5476|TrEMBL
MALGTASTRTDHARTVRDMLATGRTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADTTLTPVAHLTAVSHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWIAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSPDWDSDVARFVD
KCRAGADYAITQMFFQPESYLRLRDAVAKAGCETPVIPEVMPVTSVKMLERLPQLSNAAI
PNALKERIVTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
PHHPSRA
>A0A6B1GTM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Holophagales bacterium|TrEMBL
MAPSTNFAGAARGPSWGRWRDGWRRPAWSSRRSEWPRTRRRIRFVVKLIDKLRSAIAEER
PFYSFEYFPPKTEAGIENLYARIERMGRLEPAFVDVTWGAGGSTAELTFELANTIENVLG
LETMMHLTCTNMPRRRIAAVLDDCRARGIGNILALRGDPPRGRGAWSPIADGFSHASDLV
RFIREEHGDHFGVCVGGYPEGHPEAPSRERDLDHLAEKVATGADFVITQMFYEPELYFRF
LEECRERGVDCPIVPGLAPINGYLSFQRITGFGASAPPEIVSEIEARRFHDASVREYGQD
LLTGICSRLLEGGAPGLHFYTLNLERSVQVILDRLGIVPERIERVLPWRSATAVQRPRED
VRPIFWANRPKSYLARTQDWDEFPNGRWGDAGSPAFGDLGDHHLAFRPIRSDLARERWGR
ELHSIDQVREVFAGFCRGDVDGIPWYDWPLDLESEPLRNALVRLNLAGLLTINSQPRVTG
APSDDPAVGWGGAGGRVYQKAYLEFFVAPEQVPTLLAALDAGPSLTYHAIDRSGTAHSNC
DTVNAVTWGVFPGEEIRQPTIVDPRSFEVWKDEAFDLWLSSWAAVYDEGSESRRLLQRIH
DTYFLVNVVDNDYVDGDLLGYLLDAVQADEPPSMTIVAPVT
>F8JED3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp. (strain MC1)|TrEMBL
MAQNSERKSKLLGSGDIVVSFEFFPPKTEKMEETLWSAISRLAPLHPEFVSVTYGAGGST
RERTHSTVTRILKETDLKPAAHLTCVDATKDEVDAVARQYWSEGVRHIVALRGDPVHGAG
TKYEPHPDGYQNAADLVAGLKRIADFEISVAGYPEKHPESQSIEADLDNLKAKVDAGADR
IITQFGFDNAYFLRYLERARAAGIWVPISPGIVPIHNFKQVAGFAKRAGATVPSWLARRF
EGLEDDSATSHLVAAAVATEQVMDLVDEGIKKFHFYTLNRADLVYAICHLLGLRAARAAN
ANAA
>A0A838ISI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trueperaceae bacterium|TrEMBL
MMPPMRVSIELVPRDIETLRAQVADTLCLDRVTLTNLPDLLRFGLRSWDAALLTREQARL
AGRDLAAVPHVRAMDVELAPGWEPGARMCAGGIDSVVVVQGDPPDDVHHAVSGASSVEVI
AKLRREHPSWTIYGALDPYRQSIAQERDYALRKLDAGADGFFTQPFFDLRLMGAWRELVP
RVPVFWGVTSVTSVRSMRYWTTRNRAVFPGSFEPTLAWHRAFAADVVHFAEAHDADLYFM
PIRVKIGEWLGDVLQ
>A0A446TL05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Triticum turgidum subsp. durum|TrEMBL
MKVIEKIQEAAANGRTVFSFEYFPPKTEEGVENLFERMDRMVAHGPNFCDITWGAGGSTA
DVTLDIANRMQNMVCVETMMHLTCTNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFSCALDLVEHIKAKYGDYFGITVAGYPEAHPEVILGEEGATEEAYSKDLAYLK
RKVDAGADVIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNL
GLIEESKLSRTLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWGDSRNP
SYGALNDHQLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPETTIIDDQLVK
INSKGFLTINSQPAVNAEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFP
SLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRG
WACLFPEGDSSRELLEQIQKSYYLVSLVDNDYISGDLFAAFKEI
>A0A1I5JBK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora antimicrobica|TrEMBL
MTVVDRLGNGRTTFSVEFFPPRDDEEERVLWRAVRELEPLDPAFVSVTYGAGGSSRDRTI
RTTGRIAQETTLTPMAHLTAVDHSVAELRNVIGWYAASGVRNVLAVRGDPPGDPNGEWIS
HPEGLEYAEELVRLVRDLGDFCVGVAAFPHGHPRSADLDTDADHLVRKIRAGAGFAIAQL
FLEPEYFLRLRDRLAARGCDAPLLPGVMPITTPRVLAKFGELAGVPVPSAISDRLLPLAD
DPAGFRRAGVEVVTRLCERLIAEGVPALHFYTLNRSKATRQVVSDLGL
>A0A4U1KJ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MVIKRITHKLPDISAAPIIPASIEASPAQVLGASDLAGLFPQGVRVYLTDTGAASQDRLV
EAAAHLRNLGYEPVPHLAARRIPSSAAFVEQVRRLAGEAGVTDVLVVGGGVERPVGPFAS
SMDMLSTGIFDRCGINQIAIAGHPEGSPDFNDDTAMAALRLKRDFAERSDAAMRIVTQFG
FDPARFIAWAEGLIASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LARGHSPESIVGPIERHWQASPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGAADRAAS
PDSRAG
>A0A434STA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1A.F.Ca.IN.020.06.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARYEVDAVIQEFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A5P2VUW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces nodosus|TrEMBL
MNPLSTAAAAVGTSLLQDFSLEMTAKDVPSLEAARGSIPQGTRINVTFLGNEDLEMRLGA
ARAVKRHGFVPVPHISARRLGSRADFERYLSGLQSDGTGENVFTVGGDPAQPEGPYPDSL
SLIDSGLLQAYGVRHVGISGYPEGHPDIAEDVLWSALREKSTSLAAQGVDADVITQFGFD
VDPVLAWIERVRGEGIAHPVRIGVPGPAGVRRLMSYATRFGVGTSATIAKKYGLSLTNLM
GTAGPDRFLHALAEAYDPLRHGQVKIHFYTFGGLGATSEWIVRFRKEALA
>A0A1P8K1B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax koreense|TrEMBL
MPVQDPSFPLSLEFFPPKTAEGMVKLRGQRQALYALKPEFCSVTFGAGGSTQEGTFATVA
EILAEGVPAASHFSCIGATRATVRAQLETLRAMGVKQLVALRGDLPSGYGAGGEFQYASD
LVAFIRAETGDAFRLEVACYPEVHPQARSPEADLQAYVAKVQAGADSAITQYFYSADAYF
RFVEEARAAGADIPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQGFGDDVASIKSF
GLDVVTALCEQLRRGGAPGLHFYTMNQSAATLEIAKRLGLGG
>A0A2M7GBV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium (Candidatus Blackallbacteria) CG17_big_fil_post_rev_8_21_14_2_50_48_46|TrEMBL
MPVPFRELLASGRLILFDGGLGTMLYSKGIFLNTSFDLVNLQNPGLVQEVHELYLAAGSE
VIETNTFGANPYKLKAHGLVDQVHAINLAGARIARKAAGELAYVAGSIGPLGVRIEPLGP
TSFAEAQEAFEAQVLPLLEGGVDLFVVETFTNLDELTQAVAAIRKHSDLPILASVTVDDD
GNTIYGTPPERFTPRLDALDVDILGLNCSVGPKPMLEAIQNMSQWTDKPLAAQPNAGHPR
IFQDRTIYLCSPEYMASYARKLIKAGVQVLGGCCGTTPEHIREIARSVKALQPMRALMQQ
EQKRTVAPDLDIVPVPLAEKSRLAAAIASGRFVVSVELTPPKGCEPSAILEKARELYAHG
VDAINLPDGPRASARMSNQILSILMHQQIGIEPIPHYCCRDRNLLGMQSDLLGLYSAGIH
NILLITGDPPKLGDYPDATAVFDVDAIGLTNIVKGLNHGYDLGQNPIGKPTGYFIGVGVN
PCAVDLEREIRRYFYKVEAGAEYAITQPVFDVEALLEFLSKTASHRIPVLAGIWPLASYR
NAEFMNNEVPGVVIPEVIMQRMYEAEERGEGREEGVRIAQEMVRFLRPHIQGIQISAPFG
RLEPVFEVMKAIEN
>A0A8H3WZK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gigaspora margarita|TrEMBL
MKIIDKINAHKSTDPFFSFEFFPPKTDDGLSNLYVRLKRMSVLDPLFVSFTWGAGGSTAE
RTTEMCTTAQGLFGLETCMHLTCTNVVDEILEEALNEAKNSGIQNILALRGDPPRGQDSW
TPSDGNFLHAIDLVKCIRKKYNDWFCIGVAGYPEGHPDSDDKDQDLRYLKEKVDAGADFI
ITQLFYDVDSFVEWEKECRKIGITVPIIPGIMPIQGYNSFRRVTNLCKINIPTDILNALE
QIRHDDQAIKDYGVSLAISMITILHEKHNVNGFHFCTLNLEKSVRLILEKMGFVPTEEER
NLKRSIKRRPSVGYVANDIIRQEPDGSVPAAKPIIWKEQSEDYLGRSDDWDNFPNGRWGN
SKSPAFGELDVYGMSLRISRDQALEYWGEPKTLDDIIQIFKSYILCEIPVFPWSEDPISK
ETDVIRSNLIKLNELGYLTVSSQPAVNGVKSDDKDFGWGPKGGYIYQKFFVEFFVNQEKF
DKLIQIIDENCWITYYAAKRSHAFKTNMKEETSTAVTWGVFPGKEIVQPTIIEEVSFNAW
KEVAFELWSEWERLYPKDSTTQKLLKEIGDNWWLVNLVYNDYVNPEGVWEFFFGIE
>A0A8H4A1T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gigaspora margarita|TrEMBL
MSVLDPLFVSFTWGAGGSTAERTTEMCTTAQGLFGLETCMHLTCTNVVDEILEEALNEAK
NLGIQNILALRGKQFFNI
>A0A8I0QCK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter japonicus|TrEMBL
MIRSIDQVRADLMRESSIELLPSRILELSGVLPDLDRGLRVFVTWLPGVPFVDVLAACDL
LKLCGYLPVPHVAARTIRDTEHLRNICAALIERDIPRMLLIAGGADKPAGIFTDTVQVLE
TEIPAQAGIRTVYVAGHPEGHPQASEKQLEQYLLRKQELARAQGLNMQIITQFCFDAAPV
LDWEKRLRAAGIKLPINLGVYGLTTPKTLVRYGLACGVGQSLRFMQKQRWKLHRWFIPCN
PKDLVDAIAGSIAETPDTLFHGLHFYPFGAIARTLEWRRNLSCSGTGEPS
>A0A6N7HZ90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MHAGRFAITAEIGPPRGADAESIIHKAELLRGWVDAANITDNQGGVTRLASWGGSVLALG
AGVEPVMQLTCRDRNRMALQADLVAASAVGIPNVLLLTGDHPSFGDHPDAKPVFDLDSVQ
LVWTAQWMRDHGKLLSGKSLKPAPRWLIGAVENPFGPPERFRARRLGKKVAAGADFIQTQ
FVFDVDSFAKWMIEVRDLGLDQNCGILAGIGPIRSIRALEYIQNHVPGIHVPEDVERRLR
GVPDDQVAEEGMRICVESLQQLEQIPGVAGAHLMAFGYERGIPEILQRAGFGPRSAPNLL
SGQGSEHAS
>A0A7J9XQQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MTADRGGSTAPVSRLLVDGIVVCDGAVGTMLHSAGVPLDHSLSELNTAAPALVRDLHTAY
VAAGAHIIQTNTFEANRLRLARFGLESTVAESNIAAARLAREAAQTAERPVLVAGSIGPA
TSSSAAPSIPLHARLAALAEQVGALANWVDLLMLETFGDLDSLGHALDVAAAESDLPVIA
QLTFGDDGRTLRGETPREAAGLLGQRDVVALGANCTVGPAVLQDVVAELAAGTALPVSVQ
PNAGLPQRLGKQFRYAHNTRYFAQSAEAFVAAGANIVGGCCGTTPAHVRAVARAVAPLLP
ARPLHPATEPARRERATASSSAPVQVQAQTGEVAGLWPQPDRFDIVVGLATPSEHDVADF
VGRAQQLRAAGADLVALREPTPSRARVNPIAAALLLRERVGAEVVLPVETADRSLAALQA
DLLGAHALGLQIVVCRTGAPQVAGDYPDPAVLWDVDSVGLIRTLRGLNEGTDWRGVAMAE
RTRFSIGASLTTMAADPGHELDRAEAKVRAGAGFLLTDIVYDVEEARAVLTGLARRGIDR
PVIAALAPFDDARTLERLSFEMPHLAPRSSALVALRRRSERPDDAVDAAVEAVDELADLV
RGVVLHVPADRAEHGAALLTRVASHRARP
>A0A7V5R1W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillales bacterium|TrEMBL
PARTNEQKIVLQNTQEKLRKLNPEFFSVTFGAGGSTVAATTDTVLELKKHKTPLVIPHLS
CMGGTPDSIKSLLQQYLENDIHDILALRGDVPSGMGSVGYFRHANELIEYIKTEFDDQFN
ITVGCYPEIHPESDSKEIELKYFKQKVQAGASQAITQFFFNADAYFAYVEECQKKGIDIP
IIPGIMPITNYSNINRFCGFCGAEMPRWLKYKLQSYGDDRNSIQKFGTEFITKLCEQLLA
GGAPSLHFYTLNRSKATLDIANNLST
>A0A385TLR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus lautus|TrEMBL
MKPNLRQAWENQVLVGDGAMGTYLYQKGFPVGISYEELNLTSPEVIGNVHRQYVEAGAQV
IETNTFSANYDKLSKYGLEARVGEINRAGVRIAREAAGDHGYVVGAVGSIRAGKRSNIST
SELKRYFEEQLSVLISEGVDGILLETFYDVDEMQLALAQARMLSDLPVICQFAVEDIART
LDGFTMPDAYRILSQEGADVIGFNCRTGPNGIMRALETLNGIMNLPASVYPNAGIADYVD
GEYRYGASPEYFGKTALEFADRGARIIGGCCGTTPEHIAEISSALAGYVPSPLPTVEEAE
INRIVIHETAQEQFYERSGEPTIVDIVKERHTVIVELDPPRDLDITKFMRGAEALKKAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVVGAAFNP
NVRHLDKAVARLEKKIASGADYVMTQPVYDPELMVRLREATAHLDIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAMGVKIGKELLDVATEHFNGIYLMTPFMFY
EMSVQLMEYVWEKSGRRLTPLFH
>A0A7Z0Y2F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. diarizonae serovar Rough:r:z|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATGDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDIYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4R9RUS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.230.01.1.1|TrEMBL
MTTPFSFEFFPTKTDDGQTKLLATFDELNALKPQYFSVTYGAGGSTRERTLGIVKALSEK
SDTPITPHLSCIGDDKAKIGELLDYYKSLGINRLVALRGDLPSGMVGLGELPFAVDLVKY
IREHSGDYFRIKVAAYPEMHPQAKSFDADIQNLLNKYHAGATEAITQFFYNADSYLYLRD
ALAKKGVTQDEFPIIAGIMPITNASNLIRFADGCGADIPRFIRKQLADYGDDKKAIRQFG
FEVVVNLCERLIAEGVPSMHFYSMNQVNPNKQLIEALGLV
>C3WBE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium mortiferum ATCC 9817|TrEMBL
MKIKELFKQKQPTISFEVFPPNKIYTLEKVYEVIDELSLLKPDFMSVTYGAGGSTRRNTV
DIASKIKNINNIEALAHLTCIGATKKEIDEILKDLNKNNIENIMALRGDIPQECENKIGE
FSHANDLIKYIKEYGDFSIGGAFYPEGHQETNDLLDLFNLKTKVDSGTDFLISQIFFENE
KFYEFKEKLGKLNIKTPLIAGVMPITNGKQIRRITSMCGCSIPEKLKRILDRYEDNPIAM
REAGIAYAMEQIIELISDDIAGIHIYTMNRVEASKKIMENIGNILRKRDENYGY
>A0A0J6VK20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium chlorophenolicum|TrEMBL
MTAESVGEDEADACPKHMQFGPCGGVRPDGQCEMRPGPCAFPETVLWDGAPAEAPRVMAP
LILTDFSCLPFDTADVAATAHALADSCDAVLVGEHQNRPDFPPTLMGRLLLESGVQPWIT
LSCRDRNRVVLEQELRGLALTGVQTVLCVTGDGRAYDVRPDVTQTFDLDGPRLVALAADV
GVTAAVPETPSAPPVSGRPLRLVQKQRAGAGIAVLNHMSAPAVVADFMASARAAGLAIPV
LAAVAVITDELSAAVLQGLPGLAVDPAVVDSVLGAPDPVEAGIEAAVAEARALLAIDGVD
GVNVSGLASGAGTRAGAEIKAEVGRRIRQGREAR
>A0A238DVK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomonas sp. X19|TrEMBL
MSLSHLSFEFFPPKTPEGAVKLRAARQRLYVHKPEFCSVTFGAGGSTQDGTLHAVKEIAE
EGVAAAPHLSCVGASRDSVRAMLQRYRAEGIRRIVALRGDLPSGYGLGGEFHHARDLVEF
IRTETGDWFHIEVAAYPEVHPQARSPQDDLRHFVEKMQAGANSAITQYFFNSDAYFRFAD
DALAAGVDAPIVPGIMPITNASQLLRFSEVCGAEVPRWVRLRLQSFGDDRASILAFGREV
VADLCNQLVSGGAPGLHIYTLNQAEPTLDLLTDLGTR
>A0A431NK02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MSSSPTPRATVVDRLDVDRPVFSVEFFPPKDAAGEAQLWSAIRRLEPLDPAFVSVTYGAG
GSSRDRTIRTTERIASDTTLVPMAHLTAVAHSRAELRHVIGSYAAAGVRNVLAVRGDPPG
DPLGEWNPHPDGLTYADELVTMVRSLGDFCVGVAAFPYGHPRSTDADTDFERLVAKIRAG
ADFAITQLFLEPGGFLRLRDRLAAAGCHVPLLPGIMPLTTVRTLHRGPELSGAPLPPDLV
ARLERFSDDPAAFRAAGMDATAELCEKLLAEGVRGLHFYTLNRSPATVELVGRLGLASAR
>A0A3G2R782|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Biomaibacter acetigenes|TrEMBL
MGLKQKLESGGFAVTTEMAPPKGTDFKRFKECALAVKGMVDAVNVTDFQSAVVRASSLGA
AAILVEEGLEPVMQITGRDRNRIAIQGELLSASALGIKNVLALTGDHPSFGDNPQAKGVF
EMDSVNILQVARTLMGGKDLAGNDLAGTPDFYLGASVTPVYDPMELQLLKMKKKIQVGAR
FFQTQAVFDIELFKKFITAMGDIDAKILVGVIPLKSPGMANYMNKNVPGIFVPDEIIERL
RKSQDRVKEGLKIAAEFINEVRQQKLCDGIHIMAIGAEENVPALLEMCDLDSAA
>A0A396Q8E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. OF10-2|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTSSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>A0A0T6TY36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas allosaccharophila|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSVQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A5E5Q3C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Gammaproteobacteria bacterium|TrEMBL
MKTSFEFFPPRTEKGKQTLHQVRQELSSINPEYFSVTFGALGTTQEATLETVLDIQKNDT
VVAAPHLSCIGSKKEIIIELLDQYKAVNINRLVALRGDIPSGVRDIGDFHYANELVEFVK
SQYNNHFHIEVAAYPEVHPESKNRQTDLQHFADKVKAGADGAITQYFYDAEAYFKFVDEI
EKLGVSIPIIPGIMPITNYTQLVRFSNMCGAKIPNWILKKLELYQDDLDSLSTFGLEVVT
NLCQTLKEQGVNNFHFYSMNRSQPSLEIAKHL
>A0A7W9W8Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonas rosea|TrEMBL
MRIDALFGGERPTLSFEFFPPQKTAGAEALFQTIHQLQALQPDFISITRTGGGTEPTLEL
TLRIQQELGIRAMSHLTCLHHSQPEMEAHLETLWQGGVRNVLALRGDPENGQLVFKAPKN
GFAYANELTAFVAQRHDFCIGVAGYPEGHPQCLNLTRDIETLKAKLDAGGRFIITQLFFD
NADFLRWRERCRASGITVPIVAGIMPIENVAQIKRFVTRCGAKIPQELLLKLEAVEGNPD
EVYNVGIGHAIAQCQELLREGVDYTLNKSKATAQIGEALTR
>A0A7S9LQL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontivivens ytuae|TrEMBL
MSNILSFRRKAPAPAGLAGFLDGFSIEVMPRTAEKIADFRDLLPAGTRVYIAHIDGTPIE
EMRATAARLVNEGFEVMPHVPARIVANKAELNDWLAGYADLGVHQALVLAGGVAEAKGDF
ETSMQLLETGLFDAHGFTRLHVAGHPEGNRDIDPDGSDANVSAALGWKQAFSERTDARMA
IATQFCFEAKPVIAWAERLAAEGIDLPIHIGVAGPAKLQTLIKFAMMCGVGPSLRVLQRR
AADLTKLVLPFTPEDFLRELAAHKTANPAFGIEAVHFFPLGGITTTAEFTSAHGAAPTRA
AQA
>A0A7J0D0E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces microflavus|TrEMBL
MKLVRESGAFSVGVAAFPERHPRSADWESDVRHFVAKCRAGADYAVTQMFFRAEDYLRLR
DRVVAAGCDTPVIPAIMPATDPRQIARFAELSGATFPDDLARRLHAAGGGEEGRRIGIDF
AVAMAEKLLAEGAPGLHYITLNRSSPTSEIHRELLGSALTAPALTAHA
>A0A8J6P2G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfatibia vada|TrEMBL
MSTDNGLKSGSNLEKVLNAGHFAFTGELGPPRGTTVKEVVEKCQHLKGMVDAVNITDNQT
AVVRMSSWAACLILIKEGLEPNFQMVCRDRNRLAMQGDILGAYAHGVRNMLCLSGDHCQF
GDHPDAMGVFDIDSMQLINMVKTMRDEGKFQAGTEIEDPPQMFIGAAVNPFAEPFDWRVH
RLAKKIEAGVDFLQTQCIYNMDKFREFIKRANDMGLTEKAYILAGVTPMKNVGMARYMQK
RVPGIEVPEEWIDRLKGVDKKKVADEGIKMACEQIEEFKEMKGVHGVHMMAIEWEHMVPR
IAEEAKVLPRPVME
>A0A7W8T5P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. MM5384-R2|TrEMBL
MTFLTMNPIELSFEFFPPKTQEGIDKLRATRAELVPLKPKFVSVTFGAGGSTQQGTLDTV
VDMAKEGLEAAPHLSCIGSSKDSLRAILNEYRSHGIRHIVALRGDLPSGMGAVGELRYAS
ELVSFIRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAY
FRFVDDARQLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRA
FGLDVVTALCQRLVDAKVPGLHFYTLNAATSTKAICERLAV
>A0A4R1QFK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermolongibacillus altinsuensis|TrEMBL
MGLLDDLQTNILIGDGAMGTLLYSYGIDRCFEELNLSNREQILRIHQAYIEAGANVIQTN
TYGANYVKLARYGLEDEVKKINEAAVQIAKEAAKDRAYILGTIGGLRTLNKNTLTIDEIK
RTFREQLYALLHSDVDGLLLETYYDLEELTTVLAIARKETDKPIIAHVSLHEVGVLQDGT
HVSEALKQLEALGADVVGLNCRLGPYHMLRSLEEVPLPTSAFLSVYPNASLPEYRDGRLV
YETNPGYFKETALSFREQGARLIGGCCGTTPKHIAAIAEALRGLKPIVHKQVKQQKEAIV
VQEPPYESDPPLHEIVRKRRSVIVELDPPKKLGIQKFLAGAKALHEVGIDSLTLADNSLA
TPRISNVALGTIIKEKFGIRPLIHITCRDRNLIGLQSHLMGLHTLGMNHVLAVTGDPSKI
GDFPGATSVYDLSSFDLIQLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVQR
LEKKIQCGAHYFISQPLYCEKQIEQVYEATKHLSAPIYIGIMPLTSARNADFLHHEVPGI
TLSDDIRARMAACANDPLQSAREGIAIAKSLIDAAFELFNGIYLITPFLRYEMTVELANY
IYEKARAERKLSNV
>A0A1Q8WUH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MHDNEPTGPTAAAGSRGEALSSAETGTARRLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPAGGVTGGGHQGSAHEPEAGRCEAPRVRAVQEQTNPSECVLAHV
LDSSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRAEDVAGELRHA
DDLVRVIREVEADFFGDGRRHVTIAVAAYPATNDHIEAIEVLAAKQAAGADMAITQVFYD
AADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSSLGSASGATL
VERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDAV
DRGYLQATPGRGPSFLRCGSARATVSSHHPVQPLTTITKENA
>A0A8H5YYM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium mundagurra|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIGESRGSKTDSEIMLTMVVNNDFHDNKTIFELLKG
LEVKDLTTPATPLTESVGNGTVDTEPIANGTAATAVAN
>A0A7J9WK18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitriliruptorales bacterium|TrEMBL
MALTIRRLLATQRPSFSFEFFPPKTDEGEQQLWQAIRDLEPLRPTFVDVTYGAGGSTRDR
TLRVVERIANETDLTVVAHLTCVAVSREDVRATIRRFRDAGVRNVLALRGDMPGGPDVAW
EAHDGGLHHAEDLVRLLHEEGDFCVGVAAFPEKHPEAADLATDVKYLAQKCAAGADFAIT
QFFFDPADYFRLVRSAREAGCTVPIIPGVMPVTNVRQIERFAALSGAAFPEDLAARLRAV
QEDPQAVRAIGVEVATELAHGLLDGGAPGIHFYTLNRSTATRQIHARLNGS
>Q3SVZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)|TrEMBL
MGYAGGNAVPRMAGPTPGVSRPTAVTRARRDRCSGVFRAMTDAFAPAHDGLGARKRPTIS
FEFFPPKTEEMERNLWGTITRLAPLDPSFVSVTYGAGGSTRERTHSTIARILSDTRLRPA
AHLTCVGAPRGEIDEIVSRYRDIGVRHIVALRGDPPGGIGTAYSTHPEGYRTSADLVAGI
KRRHGDIEISVSAYPEKHPESPDIDTDIDVLKAKVDAGATRAITQVFFDNNLYLRYLDRV
RARGIDIPIVPGIMPMHNFKQARAFVTKAGTTVPAWLAEKFEGLDEDPETRKLIAATVAA
GQVQKLAKRGVDTFHFYTMNRADLVFAICHLLGIRPDAAQKAA
>A0A1V6TH12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium flavigenum|TrEMBL
MRLEQMVTWSTFARILSSSSNHSHCRPIHLKDAMEKKITEKIAALPPDANYFSLEFFPPK
TRMGFANLSARLERMAQALRPLFVTVTWGAGGSTAARSLELAEVCQRQLQLTTVLHLTCT
NMSRKLVDMALDEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNKDFTFAVDLVRYIRQT
HGDYFCVGVAAYPEGHPADNFQDVQDPARDIPSLVEKTQAGADFIMTQLTYDIEAYQKFE
EMLRSHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVTIPPPIAKRMEELKHDDDAVKR
AGVDIVSEIVGGVRDIPSPGPRGFHFYTLNLEKTVSFILEQCDLIPSYSDAGDTAIADDP
ASIPLDFPGRALRRRRASSINSQPHNRVIVDKLSVHESSQDSVHEALADSAGVPAPPPNR
STTLLISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTANTARRLWGHPV
DSKDMSTIFRRHVSGELHMVPWSEGGAEEDGEGLNAETELIRPELLKLIDGRGWWTLASQ
PAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFCSSNDYTNILKPLFAKHGHDKLTWFATN
IKGDFESSLPTQPADMELDDLGSNPESVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAF
RIWDEWRRIYPRGSPTETYLDTTKNDSWLVCVVGQQFGAGTKRGSKEEEDEVKWMWRVLA
GEEA
>I1D4R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora glauca K62|TrEMBL
MRRVVDRLASARCPTFSVEFFPPRDEADEAVLWRSIRELEPLDPAYISITYGAGGSSREG
TIRNIARVATDTTLVPMAHLTAVNHSVAELRNVIGHFAAVGVRNILALRGDPPGDPMGEW
VPHPQGLTYAEELVRLVRELGDFCVGVSAFPYGHPRSVDLETDTKYLVRKLKAGADFAIA
QLFFEAEDFLRLRDRVAAAGSDALILPGIMPLTTPRTWRKTVELSGATPPRWLSERLEPL
VDDPKAFRAEGLDTITELCERLLAEGVPELHFYTFNRSKATRELVDRLGLRSPRAEPAAV
GS
>A0A519H5I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MSHDRPTASVPVSFEVYPPRTDEGMPRLHETIRRLAAVRPDFISVTFGAGGSGGGRSLDV
LTHILRETDVPPLAHLTCVGSTYADAGEVGERGHVGLTED
>A0A014P3K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas aquatica DA1877|TrEMBL
MNVANANTSSFPISFEFFPTKTPEGAAKHVQVRQDLYARKPEFCSVTYGAGGSTQAGTFS
MVRDIQAEGMQAASHFSCIGATSDKVRAELQQLQDMGVRRIVALRGDLPSGYGLGGEFHY
ASDLVAFIRREFGDWFHIEVAAYPETHPQARSPEADLKAFATKIQAGASSGITQYFYNAD
AYFRFVEGIQALGVSAPVVPGIMPITNSSQLMRFSDATGAEIPRWIRLRLQAYGDDVTSI
RAFGLDVVTRLCEQLRDQGAPGLHFYTMNQSAATLELCDRLGL
>A0A420G8G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium deltaense|TrEMBL
MLRSETARQNGDIRLSFEFFPPKNPEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLATAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYK
PHPEGYENAAALVKGLREIADFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMDRVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGINEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A1Y5Q3P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Sphingopyxis sp|TrEMBL
MTSNLNSLAEARRAAATPLFANLDGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLAPSFV
SVTYGAGGSTRERTHATVARIAAESRVPPAAHLTCVEASRAEIDEVAQAYWEAGVRHIVA
LRGDVPGGLPYRPHPDGYANAIELVAGLKAIAPFDISVAAYPEVHPDADCPQADLDNLKR
KLDAGATRAITQFFFSPDSFLRFRDAAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMVSLFDGLDDHPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVSTAKDQAA
>A0A1W2EXN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. RU36D|TrEMBL
MAQIDENPRGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKVF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VQNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDNSKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMKKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDSVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVAESGVLKGRQPWKREAGRGDSLVADRMADIASEPPQDQQALANKAA
QQPH
>A0A0M3T9U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altererythrobacter epoxidivorans|TrEMBL
MSPTLNQMREAQRALETPLFSDLPGDIAVSFEFFPPKSDKMADTLWESVQTLKPLGPRFA
SVTYGAGGSTRERTHQQVVRIQNEAGIPAAAHLTCVEATREQVDEVARHYWEEGIRHIVA
LRGDPPDGQSTYSPYPGGYANAAELIAGLKKIADFEISVAAYPEVHPDSPDAQADIDNLK
AKFDAGATRAITQFFFEPECFFRFRDRAAAAGIDGEIVPGVMPVLSFAAVQRMSGLCGTA
IPHWMEGLFEGLDDRPQARQLVSATIAAELCRKLYAGGVRQFHFYTLNRAELSYAICHML
GLRPKGDAA
>T1A3U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
PVSFEFYPPKTPEQHEQLERTITRLRVHAPQFVSVTFGAGGSTLSYTPDTVRALREVHGL
DAVPHLSCMGGTRSEIAALLEQYRDIGCTRVVALRGDLPSGMATTGDFRYAADLVRFIRS
EHDRHFHITVAAYPETHPQAEDAHADVRHFVAKIEAGADNAITQYFFNTDAYFHFVEDAR
RAGVSAPIVPGIMPVSNFAQLRRFSEQCGAEIPRWIVRR
>A0A6H2F609|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae endosymbiont of Plateumaris pusilla|TrEMBL
MKYFCIENKEYIDKFFNKSLNKFNISFEIFPPSNYEIKSNFWKIIKTLVILKPKFISITT
HNNINNSYKNTYNFVKKIQKYVNVELAPHITCINMKNDELYNIATKYWKNGIKHIVALRG
DKIKSNKNINSLMYASDLVYFLKQIANFNISVAAYPEVHPESQNTKEDLINLKRKIDAGA
TKAITQFFFNIENYLLFRDKCISQGINIEIIPGILPITNFIQLKKLIKITNIKIPNYINN
MFKNLNEQDENICKLLGSFIAIEMIIGLKNEGVNHFHFYTLNKSEIIYAICLYLGIKPKK
IILN
>T0YSF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
RMATMGAAVPPDLVERLEAADRRGGALAVRDEGVRAALELCEDLLARGVPGLHFYTMNHS
SATRELHRSLFAS
>A0A1H8Z522|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium RM5|TrEMBL
MKISEILKNEDITISMEVFPPKSNANYDDVEAAVKEIAKLKPSFISCTYGAGGGTSDNTV
KISKTIKDLGVTSMAHLTCISSTKDKVESQIKKIKENNIENILALRGDIPKDMEFPMDNH
FRYASDLINEIKTIYPEACIGGACYPEKHPEALNKDADIKNIKKKVDAGCEFLTTQMFFD
NSVYYNYLYRLREAGINVPVIAGIMPVTSKRQMERSIELSGCIVPPRFKALVDKFGDNPE
AMTNAGIVYACDQIIDLLANGIKNIHIYTMNKPDVSREIYTILRGII
>N6YZZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera aminoaromatica S2|TrEMBL
MKPEISIEFFPPTTAEGAEKLHATREKLAALEPAFFSVTYGAGGSTRERTFATVKEIAAA
GHEAAPHLSCVGSSRDSIREILQEYAAAGIRRIVALRGDLPSGAGAAGEFRYASELVEFI
RSETGDRFRIEVAAYPEWHPQAKSPKDDLAAFKRKVEAGADSAITQYFYNLDAYLNFVDA
VRRMGVDVPIVPGIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDSDAIRAFGLDVV
TRLCEKLLAAGAPGLHFYSMNMAGPTTEICRRLGLTA
>A0A1G9PGF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. ov407|TrEMBL
MFPIRIEIIPSVGIVERVTDLVPLTTTLTVTCLPHHGIERTMRTAVQLGVLGYTVIPHLA
ARTLHDRAELTGILRDCDAAGIREVFVIGGDRKQPAGPYESALPLLEDIAQYTGGLMRAG
IAGYPEGHPSAGPVEVLDALLAKQHLASHVVTQMCFAPEKILDYAALLRREGVELPIWAG
VAGSVPRAKLVSLATQIGVGSSLKFLSRKGPLARKLLSGDHYSPQSLVSGLENQPGNLAG
IHLYSFNSLDSVPGGPGQAPISAALQTALIRGAARDN
>A0A4P9UKQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotuvimicrobium buryatense|TrEMBL
MQTQQKYPKLFSFEFYPPKTEAGEESLQAVHEKLSRLNPDFFSVTFGAGGSTRDKTFDTV
VKIQERGVAAAPHLSCVASTHENIREILHGYRSNGIKKIVALRGDLPSGMMSAGQFRYAN
ELVDFIRSETGDYFQIHVAAYPETHPQARSAAEDLKNFKRKVDAGANAAITQYFYNAESY
FYFVDACEKMGIDIPIVPGIMPITNYSQLFRFSDMCGADIPRWLRKKLEGFGDDKEQIIA
FGCDVVTRLCQQLLDNGAPGLHFYTMNQSAPTLAIWNNLNLSD
>A0A1J5QYV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MMRTYSFEFFPPKTAEGVVRLRETRKQLAQLDPKFFSVTFGAGGSTRDRTLETVLEIQRE
GFDAAPHLSCVSSSREEIRAILAQYRGHGIRHLVALRGDLPSGEMTAGDFRHANELVAFI
RQETGDWFNIEVAAYPECHPEAPSARADLAAFKRKVDAGANAAITQYFYNTDAYFSFRDE
CDALGIAIPLVPGIMPIYNYAQLSRFSAVCGAEIPRWLRFRLLDYGDDLASLRAFGLDVV
SDLCDRLLTGGAPGLHFYTMNQAGTISTIWQRLGL
>E6PHK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MDIAEQLASRRPFFSFEFFPPKDDAGREALFATIASLEALGPAFVSITYGAGGSTRARTV
ELAKQIAERTGITVLAHVTAYGQSRAELRALFDELSRAGIRNVLALRGDAPRSGEANAGE
FPYASDLISYLARSYDFCIGAACYPEVHIEAAGPEDDLAHLVEKVAAGATFLITQLFFDN
DKYFSFVERARAAGIRVPILPGIMPITNYDQIARFTKMCGATFPPKLIAELEKQREHPKA
IEDLGVAYAAVQAMELLRGGAPGVHFYTLNKSPAARAIGSALLAASAWRPVFK
>A0A372DRH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas weifangensis|TrEMBL
MVPISFEFYPPKTEEQRAQLDRTATRLKAQAPEYVSCTFGAGGSTLSYTPETIQRLRERH
ALEAAPHLSCMGGSREEIRQLLKLYRAMGCRRLVALRGDLPSGMARMGDLRYATDLVAFI
RAEHDDWFHIEVGCYPECHPQAEDALADLRHFKAKIDAGADGAITQYFYNADAYFRFVDD
VRRLGVEVPIVPGIMPISNFAQLKRFSEACGAEIPRWVGKRMQAFGDDGEAIRTFAAELV
AGMCARLIAGGAPALHFYTLNLSRPTLNVLQHLH
>A0A7W5G567|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas organivorans|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGRFAVTTEIDPPDSADPAEVLQRAAIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYATILQMSCRDRNRIAMQGEILGAAAMGAC
NLLCLTGDGVQAGDHPEARPVFDLDSMSLLGLARRMRDEARFESGRAITSPPRIFLGAAE
NPFVPPAAWRAGRLAKKVAAGARFIQTQYCFDVQKLREFMAEVVDTGVLEGPDRAFVLVG
MGPLASARSARWIRDNVPGVHIPDAVIRRLEGARDQRAEGERLCRDILAEVREVEGVSGA
HIMAYRQESTVARIIEETGVLEGRVPWYPGRDDPAELNPEAPDAAPCHLTATDSG
>A0A8E2QBL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLAGYHPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLDIYRNAGIRRIVALRGDLPSGMGLASGELRHANEL
VEFIRSETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKAQAGADSAITQYFFNADCYFY
FVERVRKLGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIDSIQAFG
EQVISEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLPRQA
>A0A5I3D844|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Berkeley|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6I6LJY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MTSSNTPSISFEFFPTKTDAGHEKLMATARRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGDVKVPTAPHLSCVGDNKQELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGSHFHIEIAAYPEMHPQARNFETDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDLDSIQA
FGEQVISEMCEKLLAGGAPGLHFYTLNQAEPSLAIWDNLKLVR
>A0A8D9ZRQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium acnes SK187|TrEMBL
MAPDFISVAYGANGSRCDRALRCTQHMVSTGLRTVGHLTCVAQSVADVEQMVADYAESRI
DHILAIRGDMLGGAGQPWVAHPWGLPNATELVRLVKWVHPEACIGREGA
>Q169G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseobacter denitrificans (strain ATCC 33942 / OCh 114)|TrEMBL
MPAPEVSFEVFPPRSIDASFKLWETAQALAPLAPRFFSVTYGAGGTTRDLTHDAAYTLHK
SSGLPVAAHLTCVGASKSETLAIAQRFAQAGITDIVALRGDAPEGSNGFTPHPDGFANAV
ELIDALARSGQFTLRVGAYPEKHPEAASQQANIDWLKAKVDAGACEAITQFFFEADTFLR
FRDDCVRAGISVPITPGILPITNWTNARKFAQRCGTSIPAWLDQAFDAAIRDDRHDLLSR
ALCTELCSDLVGEGVDKLHFYTLNRPELTREICHALGVTQAVTGIKDVA
>A0A2S9H377|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solimicrobium silvestre|TrEMBL
MPQPNFSIEFFPPKTPEGVEKLRIVRAKLAVLNPTYFSVTFGAGGTTQQGTLDTVLEMRA
EGFAAAPHLSCVGGSAESIRAILQQYKANDIHRLVALRGDLPSGYGAGGEFRYASELVEF
IRKETGDWFRIEVAAYPEMHPQARSPQDDLKNFARKIQAGADAAITQYFYNADAYFQFVD
AANKLGVNVPIVAGIMPITNYTQLMRFSEMCGAEIPRWVRLKLASYGDDSASIKAFGLDV
VTQLCERLLAGGAPGLHFYSMNQAVATSAIWQRLL
>A0A160JE48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum humicireducens|TrEMBL
MTAPTSALPSISFEFFPPKSEKMEQSLWQSIRRLAPLSPDFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGKYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPEAHPEAPSAQFDLDNLKRKIDAGATRAITQF
FFDNDVYYRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGRCGASMPAKLAETFEGLDD
DPETRQLVAATVAAEQCQELQARGVHDFHFYTLNRSDLTIAICRMLGVKAKAAPAAAAVA
G
>A0A1F8PB60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_50_9|TrEMBL
MSRFKDALNSGKFVITSEVAPPKGTNLAKMLHHIDLLKDRVDGINITDHQSSVMRFPSIG
GCLAVKERGGEPILQMTCRDRNRLALQAELLLAYTRGIQNILCLTGDAVPIGDHKEAKGV
FDLDSLQLLKTIRQMASGEDLGGNKLDGAVEFCAGAIVTPEAKPIEPQLIKFEKKVEAGA
EFFQTQAIYDLENFSKFMKHARQFPTKILAGIVLLSSARMAKYMTENVPGIFVPEALIDE
LASVPKEKVLAKGIEIAGRTIAALKKDSVCDGVHIMAIGKEEVVPDILAAAGL
>A0A7W6EDJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter undariae|TrEMBL
MALLNFRKKTDVPPVEVNPVIESFLQDFSVEVMPRTAEKVDDFRELLPKGTRVYVAHIDG
TPIEDMVATAARLAADGFCVMPHFPARIIKDRATLADWIARYQGEADVKHALLLAGGVKA
PVGDFSDSMQLMETGLFDQAGFTRLHVAGHPEGNRDIDAQGTENVDAALRWKNDFQTRTD
AKMAIATQFAFDAKPIITWADSLRDAGITIPVHIGIAGPAKLQTLIKFAIACGVGPSLKV
LQKRAMDVTKLLLPYEPTEVVSELAAHKAANPDFNITNVHFFPLGGIKTNAIWAQTNGGA
SAVPAKSS
>A0A0M2RUX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MTALNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARSFEDDLTNFVRKARAGADSAITQYFFNADCY
FYFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQA
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A0A0JM81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Knoellia subterranea KCTC 19937|TrEMBL
MAPRSIPGLLASERPSVSFEFFPPKDDASEAALWDAIRRLERVRPDFVSVTYGAGGSTQD
RTVRVTERIARETTLTPLAHLTCVGASVEDIRRVVGQYAAAGVRNILALRGDPPGNPGGE
WVAHPEGLNHATDLVHLIRQLGDFTIGVAAFPDVHPASPDLDHDVDVMVRKADAGASFAV
TQMVFDADTYLRLRDRVAAHRDLPITPGLMPVTNLKQITRMSELMGTPLPRAVVDRLEAV
AGDPDAVRSVGVEIATELAQRMLAEGAPGLHFITMNRSTATLEVHDNLGLSTGAR
>A0A482ZIK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured SUP05 cluster bacterium|TrEMBL
MKISFEFFPPRTEKGQETLRQVRQQLSLINPDYFSVTFGAGGTTQESTLKTVLDIQKDDA
IPAVPHLSCIGSEKNKIIELLDQYKAVGIDRIVALRGDIPSGVRDIGDFHYANELVEFIK
IKYGSHFHIEVAAYPEKHPQAKNIQTDLTHFSNKVKAGADGAITQYFYNADAYFRFKDEA
EKLGITIPITPGIMPITNYTQLSRFSDMCGAEIPKWILERLKYYENDLESLNKFGVEVVS
DLCQTLKSQGVDSFHFYSMNRAQPSLQIAETLV
>A0A7V5WKE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSTQNEFTRSLSNPDEFTVTYELVPGQGSGGRRVDRLLVFAEKAKADGRIKALSITDNPG
GHPALAPVAIGSDVRDRGMEPLIHFSLKDKNRNQVESHLFHYHRQGFGNLLILGGDFPRP
GYHGQAKPVFDLDSVQTLRLMRDMEEGTYQKYFGSRHPAFARISCNRGCVVSPFKVSEPE
QVWQYAKLLKKIEAGAQFIITQLGYDICKFKELIRFMRDNGLTVPVLGNVFVPSPAVAGY
MLRGKVPGIVFPDTLARIIEEEGKNSDRESRLIRAAKMICVLKGLGFSGVHLGGNGLRFD
DVRFILDTAEELTPHWDELRRDVHFPVPGTWYLYESARPEACGEKRNPLAPGRLHSRQYR
HEIAHEIFFSPPNPATRLFGGLCLLCARTRKTTAILRTIEKWIKGFLFHCLMCGDCTLAE
LTYICPQSGCPKNLLNGPCGGSRHMTCEVHPDRYCYWVRVYNRVDRSSTPERLGQTPFLP
PRDWTLDRTSSWINYFSGRDHCRLKLTRKGR
>A0A6F9B168|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coregonus sp. 'balchen'|TrEMBL
MGADWEEEEAGFNYATDLVKHIRSEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDA
GADFIISQLFFRADTFLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEI
MRVIEPIKDNDAAIRNYGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWI
EDPRRTLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGEL
NDYYLFYLKSKSSKDTLLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPL
APETNLLKDELDKVNRRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSE
NVTALLKVLKKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSF
LYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMF
ELLDNPPEEQPTEQPAEQPTEEQSDKEQRAK
>A0A831QHX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKLKESLEKKKFVVTSEVQGAVDEAPEQLVKSLELVRGRVDGVTVPEVEIEGVVGDSIKT
CEVLNKNRFEAIYQTTTRDKNRIQLQKDLLQAHDSGVENLLVFTEDYRITGDSLQEMMFF
HVDAGKLESVLQHMREGRTVDGGELGKGADFVVGSGVESGWGKNIPDLEMKEMEAMAKIG
AGYFLSTPVFDVDGFEKFLKQVNTFGIPVIAEVMILRTAGMASFLNRHIKSGMVPEWVIK
KLAKAIDKEKASIEIFADTVKGLKDLCQGVHIITIGGEEKLRHYLDAAKLK
>A0A7X1L339|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MLVKEILNSNRPSLSLEFFPPKTKAGFDKLFQIISNLMQLKPSYASVTYGAGGSTRDDTA
NLVVQIQKDMGLTVVSHLTCVGSTRDELMSILEKAAEGNIENILALRGDIPEGETVWKQI
ENGFDYAVDFVSFIKKNYPHICIGVAGFPEGHPLTPNRLKEIEYLKAKVDAGADYIVTQL
FLDNRNFYDFCERCELAGIHVPVIAGVMPITTRKGMIRMAELAEGACFPACLLRSVARAE
NDEYFEEVGIHWAAEQLLNLVNNDVHGIHLYTLNRSRAILQIFKSLGIRDATQF
>A0A7C4LZM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MNAKTPSRLEKILRAGHLAVTSECGPPRGSDIGHLAAKAEAIRRHVDAINVTDNQTSVCR
LCSLAACIRLKLMGLEPVLQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQRFGDHA
QGQNVFDLDSMQLLQTVRRMRDEGRFLGGDPIERPPAMFVGAAANPFADPFEIRVPRLAK
KIAAGAEFIQTQCIYNVERFERWMQGVRDRGLHEKAFILAGVTPLKSAGMARYMKNKVPG
MDVPDEVVKRMAGVPKDRQAEEGIAICIETIQRLKEVPGVAGFHIMAIEWEERVPEIVER
AGLAPRPAVA
>T0H9W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium lactosutens DS20|TrEMBL
MTIDDRVPLYADLAGDARVSFEFFPPKTEKMEAQLWSAIETLAPLAPRFVSVTYGAGGST
RERTHNTVARIARETPLAAAAHLTCVAASKSEIDEIADAYWQAGVRHIVALRGDPPEQGG
RFEAHPDGYAGAADLVEGLMKRHPFEISVSAYPEVHPDARDAQSDLDNLKRKLDAGATRA
ITQFFFEPDTYFRFMDQVRAAGIDAEIVPGIMPVGNFAAVQRMAAMCNTDVPAWMGRLFE
GLDDRPAARQLISATLAAELCRKLYEGGVRDFHFYTLNRAEHSYAICHLLGLRPKVAAEI
VA
>A0A7C4T936|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MELKTPSKLEKILKLGHMAVTSECGPPRGSDADLIKKKAEIIKDYVDAINITDNQTSVTR
LCSLASCIHLKLMGLEPILQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQSFGDNP
TAQNVFDIDSMQLIQTVRHMRDEGKFLGGDNIIRPPKMFVGAAANPFADPFEIRARRLAK
KVKAGAEFIQTQCIYNVPKFKEWMRQVRDMGVHEKVFILAGVTPLKSAGMAKYMKNKVPG
MDVPDEIVKRISGVPKEKQAEEGIKICIETIQELKEVEGVRGFHIMAIEWEEKVPEIVKG
AGLYPRPKV
>A0A7C1GGQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MTTQNKFSRSLLDPEQFTITYELVPGQGSGGRRHERLLEFARQTYEDGRIKALSITDNAG
GHPALAPIAIGSEVQAIGLEPLLHFSLKDKNRSQVESHLFLYHRQRFHNLLILGGDFPRP
NYYGQAKPVFDLDSVQTLHLL
>A0A829QV54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia alcalifaciens 205/92|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSTEMEQTLWKSIDRLKVLKPNFVSVTY
GANSGERDRTHSIIKDIKDKTGLVAAPHLTCIDASRDELRAIARDYWDNGIRHIVALRGD
LPDNSQKPELYAEHLVELLKTEADFDISVAAYPEVHPEAKSAQADLINLKKKIEAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPSWMNRMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPQ
>A0A836UR54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Handelsmanbacteria bacterium|TrEMBL
MLNTDPAHYDKVGYCFFPEILEQAETTALRHLLDEALSDSTDNLDRPGYVGEPHSHNLHW
LEICRHPRILDAVEAILGPNLILVYSSVFIKRPHDPTQVAWHQDNTYWPSVHGTDVATLW
LAVDDADAGADFGIELATHQCEALLAGGAPGLHFYSLNKPHAATQIVRNLALRD
>A0A7Y0F0C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium sp. DSM 109958|TrEMBL
MTTPMFSLEVFPPKRNAPVGTIYDTLDGLEGLHPDFISVTYGHGTQSDRTATARIANTIR
TEYGIPTVAHLTALYSDHEVIDQALDMFDKAGVTAVLALRGDELPDHERVGVFPHASDLV
AYIRERRPDMKVFGACYPEGHYESASLDDDIANLKVKVDAGVTHLISQLFYDNDDFYRFL
DKARAAGIDVPIEAGIMPVRGAKSVRRMAERNASRIPARLARLLDRWEGNAEALRAAGIN
YASEQITDLVSHGVDGIHLYTMNHPGSTRRIWSNVEPLFTR
>R9P122|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudozyma hubeiensis (strain SY62)|TrEMBL
MSNGVDSALPPKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADL
GPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGC
RNILALRGDPPAGQSEWEPHAAGFSRAKELVEYIREQYGDYFAIAVAGFPEGHPEAVDGA
DLELQRLKEKIDAGADFIFTQMFYDFDIFAKWVKDVRAAGINCPIIPGVMPIQTYGGFQR
ATARFGTLVPQYFHDALDPVKDDDQKVREIGTRLVGEMCKKIVGTGLGISGLHIYTMNLE
KGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRRDEKIRPIFWANRAKSYVNRTETWDEFP
NGRWGDARSPAYGDVDAYGVKLRYSNDEAKEMWGTPTSLQDVKALFQKFCAGQVKALPWS
ETPVARETSVISEKLTKMNQLGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEFF
VSPQDLDALISRIEADPQITYHAVNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVES
ISFLAWKDEAYEIGRNWAKVYEPSSPSRKFLEDMFNSYFLVNVVHNDFKANHSIFEPFLS
ASKATSTANGSLNGVASTVGNVAGQVADSLSSLVKGNGYSSGHAPAPAPAA
>A0A1W1UUZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter roseosalivarius DSM 11622|TrEMBL
MYRKQPNGFLERKTVRKRPGTVGICAAIKNRFDVDTVPHLTCGGFTKEETENALIDLHFL
GIDNVLALRGDPIKSESHFVPEPDGHAYASDLIEQVACMNKGRYLDDEQEDTFPTDFCIG
TAGYPEKHFEAPNYGSDIRFLKQKMDRGAEYIVTQMFFDNEQFFNFEKRCRAAGITAPII
PGLKPMTTKSQLTMLPRTFFLNIPEELAEAISQCRDNEDARRIGIEWCINQSRELMAHGV
PCLHYYSMGKSESIRRVAKELF
>A0A160FPI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia phytofirmans OLGA172|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFAHKVKAGANSAITQYFFNADAYFRFVD
DARQIGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCGRLIDAKVPGLHFYTLNGAAATKAICERLGA
>A0A523Y3G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSTRTPSKLEKILAAGHLAVTSECGPPRGSDPEAITRKAEMIKDYVDAINITDNQTSMTR
LCSLASCIHLKKMGVEPTLQMVTRDRNRIALQSDILGAASFDIYNILCLSGDHQNFGDSA
QGQNVFDIDSMQLIQTVRLMRDEGKFLGGDEIKRPPQMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNLEKFELWLKQARDRGLHEKVYILAGVTPFKSAGMAKYMKNRVPG
MDVPDEVVKRMSGVPKEKQAQEGIDICVETIQRLKEVEGVKGFHIMAIEWEEKVPEIVER
GGLYPRPKVIDD
>A0A3A4YZQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MNPMRTTRTDSKLEKILAAGHLAVTSECGPPRGSDAELIKKKADLIKNHVDAINITDNQT
SVTRLCSLASCIHLKLMGLEPVLQMVVRDRNRIALQSDILGAASFDIRNMLCLSGDHQKF
GDCPQGQNVFDLDSMQLLQTVRQMRDQGKFLGGDEIKRPPRIFAGAAANPFADPFDIRVR
RLAKKVAAGAEFIQTQCIYNLDRFEEWMKQVRDRGLHEKVYILAGLTPFKSAGMAKYMKN
KVPGMDVPDEVVKRMAGVPKDKQAEEGLKICIESIQRLKEVEGVRGFHIMAIEWEEKVPE
IVEKGGLYPRPDPAAL
>A0A3N5TTE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKPEELSNLQRVLSEGNFAVTAECGPPRGADSEAIRRKGAILKGYVDAVNVTDNQTAIVR
MSSIASCVHLFGMGLEPVMQMVTRDRNRIALQSDILGAYSLGIKNILCLSGDHQSFGSQP
DAMNVFDIDSVNLVNVVKTMKTDGKDMSGFALVNPPKMFIGAAANPFADPFEYRVIRLAK
KIDAGADFIQTQCVYNLDRFREWMRLSREEGLTEKVHILAGITPLKSEGMAKYMSKKVAG
MDVPEPVIKRMGGVPKEKAAEEGLKICLETVAELREMKGVHGIHIMAIEWEEMVPKIVES
AGLLQRPKAAW
>A0A351CBE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSEKPISKLQEILAKEEFAVTAECGPPRGANPEVIRKKGEVLNGYVDAVNVTDNQTAIVR
MSSIAACVHLLKMGLEPVMQMVVRDRNRIALQSDIMGAYSLGIRNILCLSGDHQSFGSQP
DALNVFDIDSMNLIRTVQTMRDEGKDMSGFDLNYPPRMFIGAAANPFADPFEYRVIRLAK
KIDAGADFIQTQCIYNMDRFKEWMKMAREEGLTEKVHILGGVTPLKSAGMAKFMNNKVAG
MDVPEAVIDRMAGVPKEKAVEEGLKICLETIAELRDIKGVHGVHIMAIEWEDIVGEIVES
AGLMPRP
>A0A4R1A8B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum sp. M341|TrEMBL
MKVTEHIKQSSGKTRFSFEILPPLKGQHIDSIFNNIDPLMEFNPPFIDVTYHREEYIYKE
LDNGFLEKKIVKKRPGTVGICAAIQNKYNVDAIPHILCGGFSKEDTENFLIDLDFLGIDN
VMALRGDAVKSEIYFRPEKEGHRYASDLVKQVKGLNSGVYLDEDLQNTSATNFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKKGAEYIVTQMFFDNQKYFDFVAKCRKEGITVPIIPGLK
PVATKKQLNLIPHRFKVDLPDDLIMSVIKCKDNKEVRQVGIEWCIEQSKELIKNGVPFVH
YYSMGKSDNIHAIASEVF
>A0A3E2KLV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter gillenii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRIIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A3N5UAK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLEKVLTAGHFAFTGELGPPRGTDADEVRKKASHLKGMVDAVNITDNQTAVVRMA
SWAASLIILQEGLEPNYQMVCRDRNRLAMQSDILGAYAHGIRNMLCLSGDHQKFGDHPQA
KGVFDIDSMQLIGMVKKMRDEGKFLGGTEVGHPPKIFIGAAANPFADPFEWRVHRLAKKI
KAGVDFIQTQCIYNMEKFRTWVKQSNDMGLTEKVYLLAGVTPMKSVGMAKYMKNNVPGMD
VPDELIKRLQGVDKKLQADEGIKIACEQIEEFKQMKGVAGVHLMAIEWEHKVPEIAERAK
MLPRPVV
>A0A3A4TAL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MDLKRSLEAGDFVVIAEMEPPKGVDITAMVSNATKVKEEVAAFMVPEMSNAVMRMSALGG
AMILQGKRMDTIMQVCCRDRNRIALQADLLAASACGIRNIMAVTGEAPSFGDHHQATAVY
DITIDELLQTIQGLQTGKDMAGIELTGSPEFLVGSTVNAGLEGSALSQEIEAMKRKIDAG
VRFFITPPVFDVAAMEPFMCETASQHIDTKHIHIIPSVVLLKSLGMARYMAKNMKHIRIS
DALIKRIQNAPDKVRECVRIASETVSDIKSNGFSGAMISTMGWEDRLQDIIHGI
>A0A2S2JK21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus micheneri|TrEMBL
MSKQILSVEIAPDLLQIKSMRYYLNKWQPDFVSISNLSRFSFDNITQCASYIQKALNIPV
VIHLTGISHNKREIDESLKILRQNNISNLLLLRGDKHGHIKNYFPYANELVNYVKSKNDK
FKIMGACYPEVHPEAQSLVEDIQHLKTKVNAGCTQLISQMFFDNQKYYQFIKETNKQNIK
VPILAGIMPITEMQTVNWLKKIKMNIPQFVQKNNDLKQAGIKFTIEQINDLYKNNVDGIH
LYTMNNWSATDEIIKNIKRSELNE
>U1LVH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas rubra DSM 6842|TrEMBL
MALSLQEKILDPNQGVYLIGTTPPKSGTEQDKVERIATKLLDRLHEIEYDGVIIYDIQDE
SSRTNVPRPFPFKETVDPCEYSRLVKSLSKLDVITYKSVAQRDSAEFNQWLSTAKQEFGL
NNLVLVGSPSSQGKINLPLPEAYQALAQHEENFFLGGVTIAERHASKRNEHERLIEKTTQ
GCEFFISQAVYDAQATIDLITSYARTCKQQGIAPKRLILTFTPCGGEKTLQFMEWLGISV
PEATKWRMLDADNTLSESIRICRENLDSILRSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKATMELTLAEKQIA
>A0A8H3EJX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gomphillus americanus|TrEMBL
MHISEKLRQAEKARKPIFSFEFFPPKTDQGVQNLYDRMDRMHDLGPAFIDITWGAGGRLA
TLTCEMVNVAQSVYGLETCMHLTCTDMERKKVDDALQEAFNAGCTNILALRGDPPREQEK
WEAIEGGFHYAKDLVQYIRKNYGDHFDIGVAGYPEGCDDNQDPVSLMDHLKQKIDAGGTF
IITQMFYDVDLFLDWVGRVREAGITVPIVPGIMPIQTHAAFLRRATWSNCQIPPEWTKVL
DPIKNDDAAVRKAGKTLVAEMCQKILDAGIWSLHFYTMNLAQATKMTLEELGLVSADGHI
TKKALPWRQSKGRNRREEDVRPIFWKHRNKSYVTRTQDWDEFPNGRWGDARSPAFGQLDA
YNIGLRGSNEYNIKLWGQPSSLREVNEIFVGFLEGKYSSLPWSDGGLSSEINTIKPSLID
LNKRGFLSINSQPAVNGIKSSDPVHGWGPHGGYCYQKAYLEFLMPPTLLETLIQRINSDT
NMTFYAVNQAGDLRTNAPSDGPNAVTWGVFPGQEIVQPTIVETISFLAWKDEAFRLGMDW
ARCHPITSPTRHLLEGIMNDWYLVNVVDNDFHASDAIFKLFDGLEVDKLDDKVDVPPNGV
HKHEVNGT
>A0A7S3MHR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Favella ehrenbergii|TrEMBL
VRAKGIKAPIFPGIMPLNAYGGFKRMTGFCKTRIPPEMAKKVAELSGDDKKAEFIDFGLD
YMTDLCKKLVDSKLVPGLHFYALNSSERTFQIMTRLGYFMPQ
>A0A7M4DRE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Occultella aeris|TrEMBL
MGNTAVGAPAAPPSAAVLEVRAIAARRPLVLTGLPVPPLDSGAFAVAADHLAGVADAVLT
GDSARARVQFPPSYRAALMQQHGMRGWLGINCRDRNRVAIEGELLAIADCGAAGVLCVTG
DPVTAGHRPDAKGVFDLDGISAAHLASRAGLFTAVPEAPLSAPVQGRALRALHKQQAGAE
LLFLQYAGDAGRHAEFIGELRDVGCTLSVLPGIPVVIDHDGAAVLASFGDAVLPDGYVQR
VLDAVDPFAEGVRAAIEFGQSLLALTDVGGVVAAGGASPGQDAEFARALGIIARELGGGS
>A0A8F6HQJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Skermania piniformis|TrEMBL
MERGRDGRGEVGSPVPTVVERLHACSGALPPFSVEFSPPRDGAAESRLWRAVRVFEGMRP
AFVSMTYGAGGSTRDRTVRVTGELAEQTTLLPVAHLTAVGHHIGELRSMVGAYADRGIRN
ILVLRGDPPGDPTGEWRRHPGGVEYADELVRLVCELGDFHVGVASFPEGHPRSPDLETDT
KYLVGKLRAGAEYSITQVFFDVEHYLRLRDRVAAADPVEAMKPIIPELMPITSLRSVRAM
LRLSGSALPSDLERRLTAAAGDGPEENRAAVREVGIEVATVMAQRLIDEGVPGLHFITLN
FAKATGEVLANLGYGARGGGVGVASA
>A0A7J9QYL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilaceae archaeon|TrEMBL
MTIRYEANPPKILPDGDIDKSIKKFIERIKDISKKCDAIHLTENVLGFHRVSPLEVGKII
KKEIPDLPITVSLRVRDKSEEEISEFVHNCIEIGFSGILILMGDPSQTGKMDSGEIPSLT
VKKLKEKNIDSKIDLYLSVSNKPNFSKLGKKTDAGPRGFMTQVVQNVEQVQALADNLKEF
SVIPIILFPSEKNEKSAKFLDLDLELYSQEFEELLKKSHEITGDVLLTSPNDFTGLNEFL
GKTSF
>A0A6M1LMT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falsiroseomonas algicola|TrEMBL
MDQAYPGTLQRWLTGPRVAGLPVPSEMPPPKLSFEFFPPKNEALEQSLWAAIRRLEPLGP
RFVSVTYGAGGTTRTRTHDTVARLAKETSLTPAAHLTCVGATTAEVDEVARAYLEAGVRH
IVALRGDPPAGASQYTPHPGGYAQAEDLVRGLRRIGDFDISVGAYPETHPAAASASADLD
FLKRKIDAGATRAITQYFFDTDIYLRFIDRCAAAGITVPIVPGILPVSNFSQVKKFSAMC
GASVPAWMGKLFEGLDEDAETRRMVSAAIAAEQVRLLQANGVDEFHFYTLNRADLTYAIA
HLLGARPKAA
>A0A6I1F9Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. B1-b2|TrEMBL
MTLLEDLKTRILIGDGAMGTLLYSYGINSSFEKMNISHPEEVFRVHQSYLSAGSTVIQTN
TYGANYIKLARYGLEDSVKKINSEAVRIARKAAQKDAYVVGTIGGIHGSGMGVDMNEEIK
RSFREQLYCLLLEGVDGLLLETYYDINELETVLRIAREETDIPIITNVSMHEPGVLENGL
ELSVVLERLENLGADVVGVNCRLGPNHVLKALESVPIPKKAYLSAYPNASLPEYREGRLQ
YKSEPDYFEKFALHFRNEGVRLIGGCCGTTPEHIRALAEGVNGLVPIKEKIVKKRPKLVI
TETKQQNERTLFEKVKGQKSIIVELDTPRDLNTNKFFEGAKALKDAGIDGLTLADNSLAS
PRICNLTMAAAVKREIGLSSIVHVTCRDRNLIGLQSHLMGLHTLGIRDLLAITGDPTKVG
DFPGATSVFDVTSFELIKLIKQFNEGISFSGKSLKQKTNFHVATAFNPNIRNIQKGIERL
EKKIEYGADYILTQPIFCREKLMEIAKAIQHINAPIYIGIMPLTSTRNAEFLHNEVPGIK
LTDDVRKRMAATANNPEQAVQEGLLIAKELINTAIEFFNGIYLITPFMRYDLTVELAKYA
QEKTTKIEKLVRADFS
>A0A6I1HLD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. FT14W|TrEMBL
MHPAQPRPAGNITHAYSLEVSAKDMPALSAAAPRIVPGSTIAIPYLPREDNAARLAAVRA
VRKLGFEPMPHFSARRIASLAEFESFVQRAVAEAGVERCFVIAGDPSTPLGPFSDSAALI
DTGVFERAGIKVIGVGGHPEGHPVMSTADQWNVLERKCRSIAQRGMTPLIVTQFAFDADI
VLTWLKALRERGMDHPVRVGVPGPASIAVLARYAALCGVSACASMWSKYGVSIGKLFGTA
GPDLFVERLAAGLTAAHGKVSLHFFPFGGIAQSVKWIEQYRSRTHPASG
>A0A2J9PLH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aerococcus viridans|TrEMBL
MTDFQRGNGTSLSFEVFPANTQVGTKKLIQTLNELQDLQPNFISVTCSNNKANIEETTVK
IADYVTNTLRIPTIAHLPAAYLSKQQVSTILGQLEKLGIRHVLALRGDIVEGIPPKRDFS
YASDLVSFIQEQAPYFDISGACYPEIHPDSDNRISDIKHLRKKVEAGCSQLITQLFFDNE
QFYQFKEGCSLAGIDAPILAGIMPIVNRKQALRLIKVSSSQLPKKFLAILEKYEHNPVAL
REAGLAYAIDQIVDLVTQGVDGIHLYTMNQSDTARQIHQATKSLFQTTELLGV
>A0A250V9A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces olivochromogenes|TrEMBL
MLATGKATYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSVTYGAGGSTRAGTVKETEQ
IVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVPHLKGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDVDVAHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVVAAGCTTPVIPEVMPVTSVKMLERLPKLSNASFPDVLKERILTAKDDPAAV
RSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGLHHPQQA
>A0A5K7YXF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina widdelii|TrEMBL
MKLKEALEKKKFVVTSEVQAPMGDDDPEALVENLKRVRGRMDGVSIAEVELEGVVGDSIR
TCELLNANRFDAIYQTTTRDKNRIQLQKDLTLANESGVENLLVFTEDYRISGESLQETMF
FHVDSGKLASVLEHLKDGRTVDGKQLEKNIEFIMGSGVESVWGKNVPKQGMQEMETMREM
GTGYFLTTPIFDLDQFQKFLKQVKTFDIPVIAEVMLLRNAAMARFINRHFKAGLIPDWVV
QKLDKAPDKKKASIELFADTIKGLRDICDGVHIITLGGIDKIQPYLDAARIR
>A0A0J6VP61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium chubuense|TrEMBL
MTAELAAEQDADGCPKHMRFGPCGGVRPDGQCEMRTGPCVFPETVLWDGATAEVPRVTAP
LILTDFSCRPFDAADLAATADALADSCDAVLVGEHQNRPDFPPTLMGRLLLDAGVQPWIT
LSCRDRNRVVLEQELRGLALTGVQTVLCVTGDGRAYDVRPDVTQTFDLDGPRLVALAAAL
GITAAVPETPSAPPISGRPLRLVQKQRAGAGIAVLNHMSAPTVVADFMAAARAAGLAIPV
LAAVAVITDQLSAAVLQGLPGLGVDPAVVDSILGASDPVEAGIEAAVAEARALLAIDGVD
GVNVSGLASAAGARAGAEIKAEVGRRIRRGREAL
>A0A1F2YCN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium RBG_19FT_COMBO_70_19|TrEMBL
MLRPRGRRSRPRSEPMSVARSRLHQLFLSDEFVVTAELQATDSADPASVLELADLLRGRV
DAVNCTDNSSAHPHISGIAAAHLLIDAGLEPVLQFTCRDRNRLALQADLLGAAALGVRNV
CLMTGDDVSAGDHPDAKPIYDLDSIHLLRIARIMRDEGTYLSGRELDAPPSFLIGAVENP
FAPPLEFRPMRLGKKIEAGAEFIQTQVCFDVPRLRLFLARAGDLGLLGAVPILVGVFVPR
TARATRYLRDQVPGIDVPDGVIERMDAVPPDRQAEEGIRIATEIVNEVRDLPGIRGVHLM
AIRNEAGIRRVLDDAGLLPRPEPVGSVPVG
>A0A167TZU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporothrix insectorum RCEF 264|TrEMBL
MDKITDKIAALPPDACYFSLEFFPPKTTMGFANLRGRLDRMARALRPLFVNVTWGAGGST
AQKSLELAEICQRELGLTTCLHLTCTNMSRQTIDKALEDAKALGIRNILALRGDPPRPTE
YRDEDAAGGDSNNNNNNNSSNNNNNDAATNPEVEFAYAVDLVRYIRKQHGDYFCIGVAAY
PEGHAEESHPLGQSLEHDLPYLVEKVQAGADFLMTQLFFDGAAYEHFETVLHDHPSGAFK
DLPLLPGLMPIQNYQMIKRTTKLSHASIPDALMERLEAVKKDDEKVKSVGVDILSELVEQ
VKGIKDRLRPDRPKGFHFYTLNLEKAVSFIVERTHLIPPSTPVDGEAAATAATVAALARN
AAAANAAEVAVVDDVAVSSTPSIRVNGAPPALLVDGQQPPARRESSIGSDPRNRVIVPGP
SASHPDYEATALEASVPAGPVNTRANTLAISEGEGVLGREATWDDFPNGRWGDARSPAYG
EIDGYGVSLHMTVNQALKLWGCPTQPADISQLFIRYLRGELPAIPWSEEEFNAETATIRD
HLVRLNAKGWWTVASQPAVNGLPSSDATFGWGPPHGFVFQKAFVEFFVPAADWAALRSRL
AAPAVRDVTCYYAVNAAGDFQSSDASGGLGAGAGGSGDDGAGDEEGVREASTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWREWAAVYPKGSATDKLLEKTQKDCWLVNIIHHD
YIQKDALWNLLFE
>A0A212LTK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Sporomusa sp|TrEMBL
MSEAVAIDKQTVLKTESKLEKLYSLGHFVVTGELGPPQHSNGHELEHHAHELKDIVDGFN
LTDNQTAIVRLSSIAAGVHVLKGGGVPIIQMTCRDRNRIAMQSDLLGAYSIGIRDVLCLS
GDHQSFGNHPTSKNVYDVDSVQLISMVKKMRDDKKFLSDAVIKTDEPRFFIGAVENPFGD
PFEFRAIRLEKKVNAGADFIQTQAIFDIEKFARFMEMVVARGIHERTKITAGILPVRSVK
ALQYMKKDVAGMEIPDSLIERMKKTEDPKKEGIQVAIEMCNELKKIPGVAGIHIMPVGWE
AALPEIVKGAGFLPRPKA
>A0A086GTI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces scabiei|TrEMBL
MGTAGLRALLGSVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLTARLAAH
GHRVVPHVPARLLRDDAHLKDVVDRLREAGVDDVFVPAGDADPPAGAYDGALPVLRGLSE
LGAPFARVGVTGYPESHPLIHDDVTVQAMWDKREHATYIVSNLCFDPRVLEEWIARIRGR
GISLPVHVGVAGPVQRAKLLSMATKIGVGESTRFLTKHPSWFLRFATPGGYAPERLLTRA
GEALTAPESGVAGLHLFTFNQIAETEAWRRALLERLGG
>A0A2N8N8W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella sp. oral taxon 808|TrEMBL
MDRVIDLINHSRGTAFSFEILPPLKGNSIRSVYRVIDKLREFDPKYINITSHHGEAVEVR
GADGTVRTVNLRKRPGSVAIASAIQNRYGITAVPHLVCKGFTKDETEYGLIDLNFLEVNN
LLLLRGDTKRLREPDNPELYHAHATDLQRQVNDFNHGIALDGSPIADIETPFSYGMACYP
EMHEDARSMDDDIRYAKLKVEQGAEYLVTQMFFDNAKYYAFVDRMRAEGVTVPIIPGIKP
IVLRNQLEVIPRIFHCTFPPEFAAELGRCRTDEEATEVGVEWCTMQCRDLKAHGVPSIHF
YTLMASDSIRRVAREIY
>A0A0Q3KNK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea thiooxidans|TrEMBL
MMNAFRPSRHGSRRPRVSFEFFPPKTAEMEVALWESVRRLEPLGPSFVSVTYGAGGSTRE
RTHATVKRMVDETALKPAAHLTCVSASKAEVDDVIRSYWDAGVRHVVALRGDPAGGLGTV
YEAHPEGYQQTCDLVAGLKRIGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAI
TQFFFDNDVYFRYLDKVRARGIEIPILPGIVPVQNFKQTAGFARKTGASVPEWLADRFEG
LEDDAATRRLVAAAVCAEQVLDLIDRGATDLHFYTMNKADLVYAICHLVGLKPEKQAAQA
VAAE
>D3V6U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus bovienii (strain SS-2004)|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPSTTAMEQTLWNSIERLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKDKTGLDAAPHLTCIDANREELRNIAHDYWESGIRHIVALRGD
LPESNGKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A6P1NEU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bombella sp. KACC 21507|TrEMBL
MPAYHNAGHRPEISFEFFPAKTKEGHVALLETARNLASLSPSFMSVTYGAGGSTQERTLE
TLSDMASELSVPLAGHLTCVGASKDEVHKVAQAYWDAGIKHILALRGDPPPVNGKPTAFQ
PHPQGYKSACELVKGLKKLAPFKISVAAYPETHPQAISSEADIDNLKRKFDAGADQAITQ
FFFSPEAFLKFRDKLSKIGVDKAVIPGILPISNAEQAWKFATICGAAVPKELRDLFEGVD
EYPAVRTRLAAAIADRICQTLRSEGVEHFHFYTLNKSAASTSLSLLLGRHLS
>A0A6P3BL89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia contaminans|TrEMBL
MKTIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVM
>A0A7I7JYF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium duvalii|TrEMBL
MTVDCPKRMHYGPCGGVRADGQCEMRSGPCAFPDVVLWPDTASHPGPLADPPLVLADFSC
TPFDAHDAGLVAALLAPTCDAVLVGEHQNRPDFPPTLLSRLIMDSGALPWISLSCRDRNR
VVLEQELRGLAYLGVDTVLCVTGDGRGYDVRPDVTQSFDLDGPRLVAMATEFGMTAAVPE
TPTAPPVDRRPVRLVAKQHAGARVAVLNHVTSPSTVAQFMAAARAAGLTIPVLAAVAVFT
DSVSAAVLQGLPGLELDAGVVERVLSADDPIEAGIEAAVAEAQALLSIDGVAGVNLSGSA
SASGSRRGAEIKAEVGARIRARA
>A0A2E3HT09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MSTWRKSSFRSLLQETNTFVACVELVNSRGVIAERGGARVLKLARELSQYPQIHALCITD
NAGGNAMLSGDTLGTDLISRGQEVVIHLSCKDWNRNGLQSQAWKLASEGFNNVLALSGDY
PVSGYKGQSSAVFDIDSVGLLKMISEMNAGLKVSVGQSKKNQVLKRTRFFSGAVVNNHKR
YEREVMPQYFKLRKKIENGASFIINQIGYDARKQDELLKYMNYSGLHVPVLYNVYVLSLA
AARFFHADNIPGVTVTDDLLALAEKQADSADKGKAFFLEFAAKQCAIAKGLGFRGVYLGG
HLKASDYKKVLEIADQFGEDDWKDFAKEICFSQTDEFYFFEPDLTTQLSSTEVNREYLHS
KHLKATQVSKQSIPLSYKINRTIHDLAFKKGTAGFSLGKKISQAIERKNKGTQKILHGLE
QAVKIAAFDCQDCGDCSLPDIAYLCPESQCAKNQRNGPCGGTKQGKCEVGEKECIWSLAY
DRLKAYDEEEQMLDGPVVFRDGALKGTSAWINTFLGRDHHGKDKK
>A0A6G3Z0N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. SIO1D8|TrEMBL
MNHFISAIQTGQFLITAEVTPPKGSNPKRMLQMALTLKEWVHAVNVTDGSRAVLRASSLA
ASVMLKQLGIEPICQTTCRDRNSIALQADLLGAQMLGIHTILALTGDPVKAGDHPHARSV
FELESVRLLRLINKLNQGFDLNDQPLTDQQTNLLVGAAVDPQLKSWSTLQRRFERKVEAG
AQFFQSQLISDFDRLAQFMDQIAKQHEKPVLAGIFLLKSAKNARFINKYVPGVQIPQETI
DRLDRAQDPLHEGMVIAAEQVKIARQLCQGVHMMAVKREDLIPQILEMAGLKPLELATIR
KTTSLKSTVTHGLVA
>A0A2D2E9T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella osloensis|TrEMBL
MTTLTTPFSFEFFPTKTDDGQTKLLATFDELNALKPQYFSVTYGAGGSTRERTLDIVKAL
SEKSDTPITPHLSCIGDDKAKIGELLDYYKSLGINRLVALRGDLPSGMVGLGELPFAVDL
VKYIREHSGDYFRIKVAAYPEMHPQAKSFDADIQNLLNKYHAGATEAITQFFYNADSYLY
LRDALAKKGVTQDEFPIIAGIMPITNASNLIRFADGCGADIPRFIRKQLADYGDDKKAIR
QFGFEVVVNLCERLIAEGVPSMHFYSMNQVSPNKQLIEALGLV
>A0A373LPV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. AF36-5BH|TrEMBL
MNIADIFKKKTVFSFEVFPPKKESGVETVYNTLRELKDLNPDFISVTYGAGGSGIAKATT
VDLCAKIKNELNTETIAHLSCLYNSKGDIDRILNDLNEKGVKNILALRGDANPDYEVKHD
FKYASDLTEYIMSKNMGFHVSGACYPETHQEATNIVEDIKNLKIKVEAGADHLISQLFFD
NNVFYDFIEKVRVAGIDVPVEAGIMPVTNKKQIERMVSMCGASIPAKLSKVLQRFGDDPV
AMRDAGISYAIDQIVDLVANGVDGVHIYTMNDPYVAKRISDSVTNLVKNK
>A0A3N0DWB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmoricola solisilvae|TrEMBL
MASGRSTSIATLLGQGERSFSFEFFPPKDAAGEEVLWRSISELEELRPTFVSVTYGAGGS
TRDRTIEITGRIARETSMTPMAHLTCVGHTVEEIDDILDSLAAAGVQNVLALRGDPPGGP
GTPWTATEGGLEFAAELVGLIRRRDDVSVGVAVFPEGHRDSTSLEADVAVMKAKYDAGAQ
FGITEMVLRASDYFGLVERCRAAGVDMPIVPGIMPILAIGSMKKMVELSGREMPTEILDR
IEPLAEDPEAVRAEGIRIATELCDELLAGGAPGLHFYTLNRSKATREIYSSLAVNA
>A0A2Z3J1I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinisphaera sp. LB1|TrEMBL
MTSDEKTGMGRALARPDFEIMPIKNGLDAARNLPAGAIATVTCSPDQGVDGTVEFAAKLQ
AMNLTAVAHLAARRIVDRNHLDRLLTRMDDAGVRHVFVIAGDRTDTPGAFASGYELVRTL
RDSGAELASIGVPCYPEGHGFIDDATLSQALVAKAEHADYMVSQICFNAQSTLDWLRRTR
RESGVSLPLYVGIPGVVARTKLINIAMRIGIGDSIRFLRKNAGLIGGLISGSKYRPDALI
RDLAAAFDDRSLNLAGLHINTFNQVEATEAWRQEQLKAWHMENAVGDAAGYD
>S9Q4L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger mucosus DSM 16094|TrEMBL
MNRPEISLEFFPPKNIEGTFRLWDTVQALAPLDPRFVSVTYGAGGTTRELTRDVVAAIHK
RSDLRVAAHLTCVNATREETLGIARQFKEAGVRDIVALRGDPPKGESGFTPHPDGFAHSV
ELIEALREEGDFTIRVGAYPDIHPEAATDTADVEYLKRKFDAGASEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGIFPVENWKGARRFAEACGTKIPDWVIEAFEAATRDGRQDLLAT
ALCTELCSELLEGGVDKLHFYTLNKPELTRDVCYALGVTPEARLENVA
>A0A2T5AXX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. VMFN-G11Ma|TrEMBL
MLATGKRTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVRETEQ
IVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMAEWVQHPKGL
AYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFFQPE
SYLRLRDRVSAAGCETPVIPEVMPVTSVRMLERLPQLSNAHIPSVLKERILTAKDDPTAV
RSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLGLHHPPQA
>A0A510PF06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa 11-30S32|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGSLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A2D6DXQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibacillus sp|TrEMBL
MQYTTHISEILNQGNPSISFEFFPPKSAEASDRLFSTIHDLKQLNPSFVSVTYGAGGSTR
DLTHKLVLRIMEETTIPAIPHLTCVNHSRVEISEILSGYANAEVPAILALRGDPPEGTPD
YNRAQDAFCHAADLVSFIQNFNREISNPRKKFGVGVAAFPEGHPDTQNRLKEMDHLRQKV
DSGADYICTQLFFNNYSFLDFRDRCRLAGIHIPIIAGIMPITTKSGMVRMADLAAGVHFP
ALLQRMLLSAKDDPVAFEKAGTDYATSQCRELLAEGVEGLHFYTLNRSSATTQIATALDL
GQK
>A0A852R604|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides kongjuensis|TrEMBL
MTTGAGRSLGEIIREGGHSFSFEFFPPKDEAGEAQLWDAIRALEPYRPTFVSVTYGAGGS
TRDKTVAITGRIARETSLVPMAHLTCVGHTRAELEGILDSYVAEGVSHVMALRGDPHEGP
RADWTPTEGGLNYAVELVELARSRGDFRIGIAAFPEGHPSAESLDADADVLVAKARAGAE
FAVTQMFFRASDYFDLVERVRARGVDIPILPGIMPILNLAAIRRQGELIGTSVPEDVVER
ISAYDGDPAAVRAEGIRIAAELCDELLAGGAPGLHFYTLNRSKATLEIFEALQITV
>A0A2A8LPY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVIEINRAAVKLAKASVTEKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLDEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIASMKHAIANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISEELIDAALKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2C1JKC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2N5FK84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. UMB0893|TrEMBL
MTLLEDLKNRILIGDGAMGTLLYSHGVDRCFEELNLSKPDEILNVHKAYIEAGADVIQTN
TYGANYIKLSRYGLEDDVRSINRQAVQIAKKAAANKKAYILGTIGGVRAFKKSAHSLEEI
KRNFREQLYLLLNEEVEGLLLETYYDLEEIKTVLEIARKETNIPIITNISLHEIGVLQDG
TPLHEGLLQLEALGADVVGLNCRLGPYHMLSSLEEIPLPDKAYLSVYPNSSLPTLEEGRL
VYGSGEKYFAESALAFRNQGARLIGGCCGTTPKHIGAMAKALKGLPPVTEKKVKIRKEEI
SVTSAAERKYPPLQEMVKEKRSLIVELDPPKKLGIDKFLKGAKALQTAGIDALTLADNSL
ASPRISNVAVGSIVQQSLGLRSLIHITCRDRNLIGLQSHLMGLHTLGLTDVLAITGDPSK
IGDFPGATSVYDLSSFDLISLIKQFNDGLSYSGKPLGEKTNFSVAAAFNPNVKYLDKAVK
RLEKKIACGADYFISQPIYSESQLVDVYEETKHLKVPIYIGIMPLTSSRNAEFIHNEIPG
ITLSDSIRETMAQAGDDRAKAYQEGLAIAKRLIDAAFDLFNGIYLITPFLNYELTVELTN
YIHMKQSEVNERKITHV
>A0A2B1KT53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYIAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAIKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMIEALKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMAPKFIEQGVRLLGGCCGTTPEHIESIKRATLNAAPVIEKDTIQRPKVVH
THEKRSKAHITLAEKAKKQTTVVVELDPPKTLDTQRFFEGARVLKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVKHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDTALKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2B3QG72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKQNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1C4FYY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQTGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A842MFJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanosuratincola sp|TrEMBL
MREAFSRLISEIRAGKFVYTGEIAPGKTTRIETLVESAKALGRHVVACNVTDNPRARANM
GSLAASIAIQERAGVEAICQMTARDRNRIALTSDLLGASALGVRNVLVMSGDHPSLGDNP
SAMPVYDLDSAQMVELVRRMVDDGTDLAGNRIDGEVRIHVGVTGNPNADPLEVEIAKLER
KAQLGAEFIQTQAVFDIEVAEGFLDAVDGFGIPVLIGILPCRSSKIAEQIAKNVPGIRVP
EEYLEKLRAAEDLNERASIDEKIDQMNEEYFSGMVSELRRTARLAGVHIMGVAYGRIVGR
IADGVERKERQDGV
>A0A2C1ZJG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANAIPVIEKDTIQRPKVVH
THEKRSKSHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALVEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDTAMKYFNGVYLITPFLKYEITEHLVKYVR
AKQEVKEGIN
>A0A850C789|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MNKFLNLLSSQTLLADGAMGTMLHAHGVGFDKCFDELNLTNPAAVAEIHRAYIEAGAQLI
ITNTFGANRFKLSKHGLQDDVVEINKAGVDLAKRVVSASFREVLVAGDVGPLGVRIAPFG
RVQAEEAREAFAEQIQALSEAGVDLIVIETMSDLYEIREAIKAARQVCDLPVVASVTFTR
DDRTLLGDDPTKVARTLHEAGVDVIGVNCSGGPAQLLRILKQMHQTAPNARFWVKPNAGW
PEQVGGRIMYPADAEYFGDYALSFREAGACVVGGCCGTTPQHIAAMRKALDTNPKIDLTH
IAILPQEELAETAQEQPTKFAQKLTSGGFAISVEMDPPRGLSTHKLIAGASLLADAGADV
INVADSPMARMRMSAWAVCDVVQRKVGVETTLHFPTRGRNLLRVQGDLLAAHALGIRNVF
VVMGDPTAIGDYPEAMDNYDLVPSGLIKLIKQGFNAGVDHSGTSIGQPTNFFVGAALNLC
PPDIDNEIKNLHRKVRAGVDFFLTQPVYNPNDGPRVLETYEARYGKLDKPILAGILPLVS
VRHANFLHHEVPGVFIPEDIRKRIEAAGEEGVKAGVEIAVELVEQIKAWAGGVYVMPQFH
KYDMVAEIIEGIK
>A0A1Q4LIL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIAHVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7C7R590|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MTTPRQRFLDLITRAERPILLDGAMGTMLHAKGIGFDQCFDALNLENPALVAEVHRGYIE
AGAQVILTNTFGANRYRLAEHGLEDKVAAINRAGVELARRVVLASFREVLVAGDVGPLGV
RLAPFGRVQPEEARAAFREQMAVLAEAGADLIVIETMSDLYEVREAVLAAREVAPDLPIV
TSVTFTRDDRTLLGDAPEKVAETLRDLEVDVIGVNCSGGPAQLLRILKHMRAVAPEARFW
VKPNAGWPERLPGGRIMYPAGPAYFGEYALAFYQAGATLVGGCCGTTPEHIAAMHHSLEQ
APPREALPRLTVSLSQRREQLPPPDEPTQLAQKLQHGQFVITVEMTPPRGLSAHKVLAGA
HLLAEAGADTINVADSPMARMRMSPWAVCHLIQREVGVETVLHFPTRGRNLLRVQGDLLA
AHALGVRNVFVVMGDPTAIGDYPEAMDNYDLVPSGLIKLIKQKFNAGVDHAGSDIGQPTS
FFVGCALNLNPKDPEREARVLRRKIRAGADFALTQPVYDPEAARRFLDFYAERYGPVEIP
ILVGVLPLNNPRHAAFLHHEVPGITISEPIMRRLEQAGERAPWEGVRIALELIERIRSWA
QGVYLMPQFRRYDLVAEIVEGVRARTEQG
>A0A2A8PWI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYIAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMIEALKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMAPKFIEQGVRLLGGCCGTTPEHIESIKRATLNAAPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARVLKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVKHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDTALKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2B1EKS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTEKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKDGYLSAYPNAGLPNYVEGRYV
YEGSPAYFETMTPKFIEQGIRLLGGCCGTTPEHIESMKRAALNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPMFIGIMPLISKRNADFLHFEVPGIT
LPEEVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A4R7F8I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myroides indicus|TrEMBL
MKVTEHIQKANGKTQFSFEILPPLKGQNIQGIFDSIEPLMEFDPPFIDVTYHREEYEYKE
AGNGLWEKRTVRKRPGTVGICSAIQNRFKLDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKNETYFKPEPKGNKYASELVTQIAELNQGIYLNPELENTSKTDFCIGVAGY
PEKHMEAPNFDTDLKYLKQKIDNGAEYIVTQMFFDNSKFFEFVDKCRAIGIDVPIIPGLK
PLATLSQLNLLPQRFKVDLPDDLVAEVLKAKDNTAIREIGIEWCAQQSKELIAASIPIVH
YYSMGKSDNIIKIIRQATI
>A0A5M9JXK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monilinia fructicola|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALKPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YGAVDEKNGNTPAMDWEFEWAIDLVRYIRKRYGDYFCVGVAAYPEGHADEGHPEGQSLEY
DLPYLLEKVQAGADFIMTQLFFDVDAYDKFERILRDHPSGAFKNIPIIPGMMPIQSYQMI
KRTTKLSHAKLPSNIITRLDEVRGDDEMVKKVGVDILSEMVEHLKGTKSQYLGPRGFHFY
TLNLEKAVSFILERTDLIPDADTVAALEPELVPTIPDIADLLSIHSGSHKRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGYPSSRADITEIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGVKSSDPIFGWGPKNGFVFQKAFVELFL
PTSSWETLRSKLTSPALRDTVSFYASNSKGDFISSDKTLGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSATRKVIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLQ
>A0A0M9F6Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium langsethiae|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDAEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSVEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLERLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAVYPEWEATGLEAGGRAEAVNTRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGHPKTRQDINNLFVKHIQGELSAIPWSE
EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PANEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGSTEASPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNLIHHDY
VNRDALWEVLSS
>A0A5J6J9C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces vinaceus|TrEMBL
MALGTASTRTDRARTVRDMLASGSPSYSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSV
TYGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSVAELRHVIGQFADAGIRNMLALR
GDPPGDPMAPWVAHPEGVHYAADLVRLLKESGDFCVGVAAFPDMHPRSEDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSTQKAGCETPIIPEVMPVVGIKQLDRLPQLSNAVF
PAAVKERMLAVKDDAAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQRA
>A0A2S6FHP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas laurylsulfatiphila|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAIYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A2N3DFQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HGW-Alphaproteobacteria-14|TrEMBL
MTPTLDQLHEYRTATDAPLFSGLPGDVAVSFEFFPPKSEKMEAQLWDAVTQLKPLAPSFV
SVTYGAGGSTRERTHATVARIIAEAGLPAAAHLTCVAASKAEIREVAEQYWDAGVRHIVA
LRGDAGEPGAPFTPHPKGYASAAELVTGLKAIADFDISVAAYPETHPDAVSSAADIDNLK
RKLDAGASRAISQFFFSAETFFRFRDQCAAAAIDAPILPGILPVTNVAQARKFAGSCGAA
IPAWMGGLFEGLDEKPAARQLVAATVAAELCRRLYAGGVRDFHFYTLNRPELAYAICHLL
GKRPVGEAA
>A0A423UF86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium mongoliense|TrEMBL
MHRPAFSLEVFPPRRHAPIGTIYDTLDGLEDVDPDFISVTYGTGRSADRTATLRIARTIH
DEYRIPVVAHLTAQYLDRNQADETLDAFEAAGVHAVLALRGDRDPDRPPTDVFAHASDLT
AYIADTHPDMTIYGACYPEGHPQSKNRKDDIGALKLKVDAGAKRLISQLFYDDDDFLSFL
EIARASGIAVPIEAGIMPVTDAAQVGRMVRLCSSRVPRSLSRILERWGDDPSALREAGII
YASQQITDLVAQGVDGIHLYTMNRPAITRRIWANTRGLFATGTNAID
>A0A1F3A906|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_63_12|TrEMBL
MQVKLWAAVEKLKPLAPDFVSVTYGAGGSTRERTHETVTRIINEARLPVAAHLTCVAATK
EEVDAVLKDYWAAGVRHIVALRGDPPGGPGERYIPHPGGYANAAELAAAAKRIADFEISV
GCYPEKHPDSPSPAADIDMLKRKVEAGATRGITQFFYDNDAYFRYLDRVRAAGIDIPIAP
GVMPITNFAGIRKMADTTGATIPGRLVKLFQNLDEDPATRQLIAATVAAEQCLALAEQGV
KHFHFYTLNRDDLAYALCTMLGVRPKSPAKPSGAAA
>A0A0L6UF40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia sorghi|TrEMBL
MDAIRVYSGQMEYIELSPARLRCTANQLTRKPQQSKEMKKVVDLIQDLDDEQVYFTFEYF
PPKTIDGLSNLYARIQRMANLKPTCAHVTWGASGSTSDTSLEIAAMVQDQLAIPACLHLT
CTNIQRAHLDQTLTQAKESGIVNILALRGDPPRGTENWIPTDHEFQHAIDLVKYIRKQHQ
AHFCIGVAAYPEGTSEFDQDQELNYLKQKVDAGADFIVTQLFYNVDIFLNWVAACRKLGI
NVPIIPGIMPIQSYDGFRRLTALCKTNIPDSIHAKLIPIKGDDQAVRDFGVELSTQMIKR
LQAKGFKSFHLCTLNLERSITRLVNQLGWSSRQTKSCQPLIGPSVTIGTTEIVQGGLSVG
WDEFPNGRFGDQRSPAFGLREGYGSSLTSAFSHLTTDVHALWGTPTCLDDITNVFCAFTE
GKLSSTPWSEEPLALETSSITPFLFKLNRNGWWTVGSQPAIDGADSLDPVVGFGPEGGRV
YQKSFVEFFIPPSHLEGLLSAVEEYNKDHPEGVPQLRYYAGNCNQDQIRTNMAPGETNAV
TWGVFRGAEVVTTTLIEAQSFKTWKKQAFDIWNDWAESFEPNSTHQRLLNEIEDTYWLCS
IIDHDFKHAEHLWSFLIAHQDRLCHS
>A0A7V2LCJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MANSLFEEKLHSNEFLVTTEIGPPKGADVSEMVHHIDLLKDKVDAINVTDHQSSVMRFPS
LGGCLLVKERGGEPILQVTCRDRNRLALQADLLLAYSRGIDNVLCLTGDSIDVGDHKEAK
PVFDADSVQLLKMIKTMESGKDMGGEDLKGAPKFCIGASVHPEADFIEPQLIKFEKKVAA
GAQFFQTQGIFDLANLHRFMQYASQFDVRILAGIIVLASARMARYMNDNVPGIIVCEAVI
EELADVEKGKGLEKGIEISARMIRTIKEENLCHGVHIMAVGNEGIVPEILEQAKLPSMST
KGKRINV
>A0A7C2A4Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKSGSNLEKVLTSGQFAVTAECGPPKGTSAEVVKRKGEMLKSCCDALNVTDNQTAIVRMS
SISGCVLLKGLGVDPVMQMVVRDRNRIAIQSDILGAVALGIRNMLCLSGDHQKFGNHPSA
KGVYDIDSIQLIQIVKRMRDEKKFLNGEDISGEVPLFIGAAANPFADPFEFRVRRLAKKI
KAGVDFIQTQAIFDVERFSRWMAMARDEGLHEKAYILAGVIPIKSAGMARYMASNVAGIT
VPKEIVSRMAGAKDAKEEGIKIALEIIEQVRAIKGVHGVHIMAVAWEDIVPVIVERAGLM
PRPRL
>A0A7V7N2T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MNKPDFGLSYEFFPPKSSEQKVILENTQKQLRKTHPDFFSVTFGAGGSTLTATAETVIGL
KQHDSPKVIPHLSCMGGTPEDIRNLLNKYLEHGITDILALRGDVPSGMGSVGYFRYANEL
IEFIHQEFPDTFSITVGCYPEVHPESVSLHTEIKYFKQKVDAGVDRAITQFFFNPEAYFQ
YVDLCQKNGIDVPITPGIMPITNYSNIKRFCGFCGTDMPRWLHYKLQSYGDDSKAIQDFG
TEYTIRLCQQLLDQGVP
>A0A7V2RGG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MANSLFEEKLNSGEFIVTTEVGPPKSVDVSEVVHHIKLLKDKVDAINITDHQSSVMRFPS
IGGCLLVKELGGEPILQMTCRDRNRLALQAELLLAYSRDIKNVLCLTGDSVDVGDHKEAK
PVFDLDSVQLIKMIRTLESGTDMGGNELGAAPKFCIGATVHPEADFIEPQLIKFDKKVNA
GAQFLQTQGIFELASLRRFMQYASQFNIKILAGLIVLSSAGMARYMNNNVPGIIISQAII
DEMASVEKGKGLQKGIEIATRMIKTIKEENLCHGVHIMAVGNESIVPDILEAAELVSTPG
>A0A800A0F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MANSLFEEKLNSNKFLVTTEIGPPKGADVSEMVHHIDLLKDKVDAINVTDHQSSVMRFPS
LGGCLLVKERGGEPILQITCRDRNRLAIQADLLLAYSRDIRNVLCLTGDSVDVGDHKEAK
PVFDLDSVQLLKLIKVMESGIDIGGNELKGAPKFCIGASVHPEADFIEAQLVKFDKKVAA
GAQFFQTQGIFDLGSLRRFMQYASQFNVKILAGIIVMASARMARYMNDNVPGILVPQVVI
DELATAEKGKGLHKGVEIAARLIKTIKEENLCHGVHIMAVGNESVVPTILEAAGLVVVSK
>A0A0M2NUW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus cohnii subsp. cohnii|TrEMBL
MSQLINKLKQNILVADGAMGTILYSDGLDTCPEAYNLTHPDKIERIHRSYIESGADIIQT
NTYGANFEKLKVFGLEHKVKEIHKAAVQIAKKAANDETFILGTVGGFRGVKQEDLGLEAI
QYHTEIQVDTLIEEGVDGLLFETYYDLEELTNIIQATKRKHRIPIIAQLTALNTNYLRDG
TEINTALQRVVDSGADIVGLNCHHGPHHMQQSFSHIELPDNAYLSCYPNASLLDIENSRF
KYSDNAEYFGKVAEQLIQEGVRIIGGCCGTTPEHIQYIKSSVANLKPVSTKNVIPIKKYN
SPSHVNTQQQNLTTKVKARPTIIVELDTPKHLDTETFFRNIKKLDDAQIDAVTLADNSLA
TVRISNVAAASIIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLLNVNEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNEGINTDGDALKTKTNFNIAGAFDPNVRKLEGSVKR
AEKKIESGTHYFITQPVYSTEKIEEIYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEDILEQFEAVKDDKEKTKALSLKLSKELIDTVHKYFNGLYLITPFQKVDYTLALASY
SQSITSSKQEAIL
>A0A6I1ZM92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKTKSNLERVLEAGHFAVTGEIGPPPSADPEVIKRKARILKGHVDAFNVTDGQTAVVRMS
SWAACLIGKEEGLDPIVQMTCRDRNRIALQMDILGAAALGINNILCLTGDHQKFGNHPMA
KGVFDLDSIQFLKVVKDMRDEKRFQCGDEMAVAPNLFTGAAANPFADPFEFRVIRLAKKV
AAGADFIQTQIVYNMDKFAEWMKRVRDRGLHEKVKILAGVAPIKSVGAARYMKTKVPGMD
VPDSIIERLRGVPKERVSKEGIKLCVDIINQVRQIKGVAGIHLMAIEWEETVPEIIEAAG
LLPRP
>A0A6N4EKA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospira oryzae|TrEMBL
MKVVDHLKNANGKTLFTIEILPPLKGENIKTLFSNIDPLMEFKPPFIDVTYHREEYVYRK
KEGGLLEKLSTRKRPGTVGICAAIQNHYKVDTVPHIICGGFNREETENALIDLHFLGVDN
VLVLQGDAIKSESKFVAEPDGHKYAYELLDQVVKMNKGLYLDDELEHAAPTDFCIGVAGY
PEKHFNAPNLKTDMKYLKLKVDMGAEYIVTQMFFDNSKYFEFVDKCREAGITVPIIPGIK
PLTAKAQLTVLPKIFNIDLPEELTEEADKCTDNKSLKEVGIEWCIKQSRELMKKGVPTLH
YYTMGKSDPIYRIAKELF
>A0A851K3C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vidua chalybeata|TrEMBL
MVNETQHTCSGSSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7V1QVU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTTTPTHASAAERLRQAFAAGRFVITAELECPRDASVAHVERQARGYAPYVDAVNCTDNA
AAVVRMSPVAAAAIVARTGLTPLVQLTCRDRNRIALQSDILGAAAVGAAGIVCMTGDPPG
TGNHPDAKAVFDITSIDLMRVVRGLREGHFMSGDPVSRPPDLLVGGVENPAEGERSVSRL
AAKVEAGLELVQTQLVFDVEPFARWMEQVRAAGLHERVYILAGIAPLRRPSIARYLREHV
PGVSVPDATIERLERADDPAAEGVQVAAEVLRTVREIPGVRGAHVMSFGWIDGVRRLVDA
L
>A0A7V2LE28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSKLQQALDSGKFVITGEIGPPKGVDIERCLEDAEKLRGQVVAINVTDLQSAVMRVGSLA
LCTKLVERKLEPVFQLTCRDRNRLALQSDLLSAWTLGIRNVLCLTGDHPVLGDDRDAKPV
YDIDSVQLLKAASFLNGGHDMSGHELEGKPDFFLGAVVTPTAEPLEPQIIKMEKKIAAGA
KFFQTQAVYEPESFERFMNETQSFTVPVIAGIVVLKSAAMARFMNQNVAGINVPEELVQE
MANTKSEDRKKKAVNITARIIRQLKPLCQGVHIMPLGWDDLIPEIIKEAELN
>A0A2G6DFJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTEVLRRSQLGPYSFADEPPPGYSLPILPGHTSPGRLERVLRAGHFAVTTEIAPPDSADP
NEVYERAALFDGYVDAMNATDGSGAHCHMSSVGMCSLLTRKGYAMVMQISCRDRNRIAIQ
GDVLGASAMGVANILCLSGDGVQSGDHPEAKPVFDLDSMTALNTIRIMRDESRFLSGRKI
TSPPHVFMGGAANPFAPPLDYRPHRLAKKVAAGAQFVQTQYCFDMPMFKEYMKQVRDMGL
HEKVFILLGVGTLASAKTAEWIRSNVAGVHIPDSVIKRLKGAEKPKREGINICIEMIEEA
RELEGVHGVHIMAYRQEQYVAEIVERSGALEGRKPWHPGMYEPVAPFDGLVETIAPDSPT
AQENPL
>A0A2E9LLT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MHSVTSDPGQPLSILQGHVSPGRLERVLRSGKFAVTAEIAPPDSADAEAVYERASAFDGC
VDAINATDGSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVTN
ILCLTGDGVQAGDQPDAKPVFDLDCISLLQTVTVMRDQGEFLSGRELTTPPRVFLGAAAN
PFGPPLDYRPVRLEKKINAGAQFVQTQYCFDLERLRNYMTRVRDMGLTDRCYILVGVGPM
PSARTASWIRDNVPGVHIPDPVIKRLLSARDQREEGVRICVEMIQAVREIEGVHGVHIMA
YKQEERVREIVGESGVLEGRMPWYPGVGNDHQGQQT
>A0A101WGM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium BRH_c25|TrEMBL
MKIKELYKNKPVISLEIFPPKPEASIDTVLDTIDALSDLKPGFISVTYGAGGSSKAHTVR
IADLIKNKYNIEALAHLTCIGSTRADIEAVLEQLKKSNIENVLALRGDIPNGESFTLQDN
FHYTYAKDLINHIKESGSFCIGAACYPESHIECSDSINDLRNLKQKVDCGADFLITQLFF
DNNLFYSFMEKLDILGISLPVSAGIMPVINKKQIERITNLCGATIPPKFRRILDKYGDNP
EALKEAGTAYATEQIIDLLSYGADGIHLYTMNRPEVARRIISHISNIRSFFNESETLKNS
AE
>A0A1I5PBK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterovibrio norvegicus DSM 15893|TrEMBL
MGYSHASHLDALNQNLTDLNGDINVSFEFFPPSSESMEQTLWASVQRLKTLQPKFVSVTY
GANSGERDRTHSIVKSIKQETGIEAAPHLTCIDASRDELKTIARDYWDCGIRHIVALRGD
LPEKSAKPDMYAADLVELLKGEADFDISVAAYPEVHPEARSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIIPGILPVSNFKQASRFANMTNVRIPGWMANQFE
GLDDDPVTRQMVGASQAIDMIRVLSREGVKDFHFYTLNRAEHTYALCHTLGVRPNA
>A0A3D2YTX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAFEATGKTSFICDFSPPRSGDPQIVDQAQIDVDLISVAYNPGRAVRTNSAMLAAAIKRS
GKESVFTLSTRDMNKLAVQSQLLGAQMLGVQNVIVVQGDPFNEKDRTMVSPVNDYRPTGL
ISAIAELNAGRDFRGGQLRSPTDFCIGATIDLRRGIEEEAQLAVRKVQAGAEFLITQPIF
NVDVVARYRESYGYHAGKAGTFPIYFGLQILEKDGVLFSSVPDSVQEELEGGRSGVDIAL
DLYQKFQEA
>A0A2L0TRW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. ASNIH1|TrEMBL
MGFHSARQVEALNQSLADLGGDISVSFEFFPPNSEGMENTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLENDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQA
>A0A1I5KHC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterovibrio norvegicus DSM 15893|TrEMBL
MSRTSEPLYSSQTGMDLLTNASLEATPKQISALVASSENGQPPHWLIKGSCVYVPFLPDA
QFENAFSTCEQLLAWGMQPIPHLPARAVPSDAVLHQWLARLQDIGVTQLLLIAGDIKEPQ
GPYADTLSLLASDHLLHYGFTGFGFAAHPEGHPLVDAHTMKQALEFKCDYAKQNGLSCWV
VTQFSFDNAALTRWLDEFQVMDLGVPVFLGLAGPTKMKNLLAYAAQCGVATSAKMLTKYS
SVARLLRPWTPTEVFDALAHYQATHLNSPLKGVHLFPFGGLKQSSEWITAQKVLVNAENR
>A0A3R9EJV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio pectenicida|TrEMBL
MGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSKKMEETLWNSVQRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKTQTGLVAAPHLTCIDASREELIHIAEDYWANGIQSIVALRGD
IPPGGGKPDMYACDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKV
>A0A327V193|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. KhCrAH-43|TrEMBL
MLATGATSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRSGTVKATQD
IAAESTLTPVAHLTAVDHSVAELRNMVGQFADAGIRNILALRGDPPGDPMGPWVEHPQGV
TYAADLVRLIKEAGDFCVGVAAFPERHPRSEDWDTDVRHFVDKCRAGADYAITQMFFDPE
AYLRMRDRVVAAGCDTPIIPEVMPVTNVRQLERLSQLSDAKLPDDLKERILAAKDDPAAV
RSIGIDFATRFSAKLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A547LNR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM4315|TrEMBL
MSARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A4Q6DWR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MELVRNQMHKPEAHFRQRLLEKLYAPQYRFVTVEIGMPAGHKSQRMREGCFQLGQKGCDA
LNLADNPNARVKMHPLAFQSRLLQAGPAFMDTIYHITCRDKNLIALQTEILGAAALNIAA
VLAVTGDAVRKGPEPAKSVFEGNSLKLLEIMKQMRAGKLMSGEDLEQPIDMLMGVAYNPN
AENINNETEKLLRKIDAGADFAETQPVHSKDAFNRCVDTLAKYNIPQARFPVIFGLMPII
SRKNGEFLNANFSGIHVPESSLKEFDGVDSKEDREKIAYEQSLELAMHFSKDGTNNY
>A0A3D1YDY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKHSLHGEKNYSSSVITDISPTSMELSTGPDVDADFLSVAYNPGQSVQASSSMFACYLES
NFNMPTIFTVCPRDMNLLAIQSTLLGASLFGLNSVIVLEGDEGKHHKNMYFPVPAKSTEV
IESIKKLTKGISFSGKSLQRHIKFSIGAVLDLQTIDEKLAISLYNKITAGADFIITQPIF
SATEIELLHSVYFNKFREKIPIPLYYGIPVLGSGSLCFRDVPSEVMDLVSLYGNNLTYLH
TLMKDCKRIGVKEFYVIPPFYSNGSRDYVLAKQFIKELRQMF
>A0A4Q6EUA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MHKPEAHFRQRLLEKLYAPQYRFVTVEIGMPAGHKSQRMREGCFQLGQKGCDALNLADNP
NARVKMHPLAFQSRLLQAGPAFMDTIYHITCRDKNLIALQTEILGAAALNIAAVLAVTGD
AVRKGPEPAKSVFEGNSLKLLEIMKQMRAGKLMSGEDLEQPIDMLMGVAYNPNAENINNE
TEKLLRKIDAGADFAETQPVHSKDAFNRCVDALAKYNIPQSRFPVIFGLMPIISRKNGEF
LNANFSGIHVPESALKEFDGVDSKEDREKIAYEQSLELAMHFSKDGTNNYYIICPFTKFD
LTAKIVEYVKFGYSHVEFSDTREIRQDMSRQVETPERCKPMLVGLKSGS
>A0A849SWN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteriovoracaceae bacterium|TrEMBL
MKVTEHLDRAKNPLFSYEIVPPPRGRSVQDIIDIVEALGPVDPAWIDVTAHSSSAYYNER
DDGTIERKIYKKRPGTIGICGIIQNRFKIDTVVHLLCLGFSKEETEDALLELNFLGIHNV
LALRGDGPNYKKELSRNRSMNYHASDLVEQIKDLNAGKFLEEVEGGSKFDFCVGVAGYPE
KHFEAPNLKLDLINLKRKVDAGADYVVTQMFFDNKHYFDFVRLAREQGITIPIIPGIKVL
KSASQMVSVPKNFYIDFPDELVERITNDPKNVAHIGKEWATNQVQGLLEGGVPCVHFYIM
NDTATIVDIVKKYQK
>B6A4H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii (strain WSM2304)|TrEMBL
MMIAPQSESREKAPLADLLSHYSIEVTSRDLPSLQSMTATLPPGSEVFVAHLPKEDIGLL
VRAAAGLRDAGFVPVPHIVARNIRNRPELDTMLARLSEEAGVRHALVLGGDRDDAAGAFS
SALDLIETGLFQTYGIGRIAIACYPEGHPRIAGAVLDTALTAKVDAAARAGLDLLLVSQF
LFDQKPLLSFARRLRERGVTVPLRVGIAGPAGRTKLLKYALRCGVGASLRALRERSEIAR
NVLSGETPEELLIDIAAAQTAEPDLGISGVHFFTFGDPAQSIRWAEQQQPSD
>A0A7X3SAQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. SoEX|TrEMBL
MSNDANQQKQLNQSELEFNKKFNISFEFFPPRNKEMEAILWNSINFLSKLNPKFVSVTYG
VNSKEKNLTYNVTKNIIERTGLKAVPHLTCVDSTRQELFDIASSYWNNGISKIVALRGDI
PKCNVKPKMYCYELVALLKKVGDFDISVAAYPEVHPEAKNAQSDLVNLKYKIDAGANSAI
TQFFFNIDNYLRFRDRCVAVGIDVEIVPGILPVSNFRQLKHFAKISKVNIPLWMYKLFNG
LDNDIETCKMIGTHIAMNMVEKLSKEGVTDFHFYTLNKYEMSYSICHILGIKPIKYHNC
>V4ZVI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured archaeon A07HB70|TrEMBL
MSLTSRTPDTQTGAETLLSGARFELMPFDSFEEEIGHLPDGATVAVTTSPQLGIDTTVER
TEQAVTWGYDVVPHIAARYVEDREHLDEIARRLTEAGVTDIFVPGGDREDPAGEFTSAYE
LLVALDELGHEFDEVGITGYPEGHDFLSDETLAASMDEKRPYATYIVTQLCYDPEAVVSW
IETLRERGVDLPVEVGIPGVMNYAKLIKISRKVGVGDSVRFLQKTTGIVDFVRQAISSRG
KYEPDELIDGLAPFVDDDDYDIQGVHVYTFNQTPDTESWRLARLNG
>A0A8H6C482|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida albicans|TrEMBL
MKISEKLTQAHKGSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALEKAFKSGCQNILALRGDPPLD
GSESTGDFKYAKDLIKYIHEKYDNHFNIGVAGYPEGHPEEEDEQKTLRYLKEKCDAGADF
IITQMFYDVDNFISWCSKLRKIGVDIPIIPGIMPISTYAAFIRRAKWSEIAIPQHFLDAL
DPIKDDDFLVRERGTELVSEMCNKLLQSGYVNHLHFYTMNLEKATVMILEKLNLIEAIKS
HDVVGGSELPWRKSLHPERSKESIRPIFWQHRKYSYISRTATWDEFPNGRWGDSRSPAFG
DIDLCASELLRQSPKKAFELWGLPQSLAELSGIIINYLKGDLKSLPWSDGPVGDDTKVIV
DDLIYLNQHGFFTMNSQPALNAVKSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDH
VEEFNVKGAESSSAFISYYAVDKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSF
LAWKDEVYRLFTEWAKIASSNLVEANQTQVDEFVQLMKKFGDEFVLCNLVNNDFVDGNST
LFDLIKRLNIDDLN
>A0A6G2LXL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4956|TrEMBL
MALGTASTRTDRARTVRDMLATGKRTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADTTLTPVAHLTAVEHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNAVF
PDALKERILAAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A7Y9U6S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerotilus montanus|TrEMBL
MTPTASLPLSLEFFPPKTPEGVTKLAAVRQALYALQPQFCSVTYGAGGSTQDGTLQTVQA
LLDEGQDGASHFTCVGATRESVRERLAQFRAMGMRRIVALRGDLPSGFGPMGEFRHASDL
VAFIRAETGDHFHIEVAAYPEMHPQARSPQADLQAFEAKVKAGASSAITQFFYNADAYWR
FMDEVRRLGLDIPVVPGIMPITNSSGILRFADGCGAEIPRWVRLRLQSFGDDTASIKAFG
LDVVTDLCERLRAQGVPSLHFYTMNTSATVLELARRLGL
>A0A118PWW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pyrrocinia|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNTAAATRTICERLGA
>A0A1Q8LLE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. Ae717_Ps2|TrEMBL
MTDGFRIICEIEPPTRPDLTHARHQIGVLTPVSDAFLIPDNHIGRATVSSIAVANEVRAM
GGAGIACVNSRDRNLLGFRRDLLTAAAYGVDQFLFVQGDKPSVGDRTGELTVRTMIEEAR
AATGQDAFAGVAPFRLGVTAGHRRRMAAWKQAADFVFVQVGYSVEAFLQWREANPMDLPV
YAGVMVLASAGMATRLRASIPDIDIPDELVHRVSDDPAAGVDAACEQIRALRDTGAFAGV
HLVPVSRFREVAARLERERR
>A0A4Z1RFB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas yindakuii|TrEMBL
MIPLSFEFYPPKTDEQREQLDRTARRLKAHAPEYVSCTFGAGGSTLSYTPETVRRLRQEH
GFEAAPHLSCVGGTREEIRELLKLYRAIGCRRLVALRGDMPSGMGHAGELRHAADLVAFI
RTETGDHFHIEVACYPETHPQADDAHVDLRHFKAKVDAGANGAITQYFYNADAYFQFVDD
AHRLGVDVPIVPGIMPIANFSQLRRFSEACGAEIPRWIARRMQGYGDDADAIREFGADLV
ARLCRRLIEGGAPGLHFYALNLARPSQAVLARLDLAEDRPSLAPPA
>A0A1X6N9Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Postia placenta MAD-698-R-SB12|TrEMBL
MKLCQKIAGYKDARPFFTFEFFPPKTDQGFDNLLPRISRLVSLNPLAVNITWGAGGTTKD
RSLELAGITQTDHGVDTILHLTCTNMKQGLVDDVLRDAKARGIQNILALRGDPPRGEEYW
IPTDPRFTHGADLVSYIKSSPEFSSDFCVGVAAYPDGHPDRETDEDGELEHLKRKVDAGA
DFIITQLFYDVDTFLQWVKRVRQKGIQVPIIPGIMPIQTYASFLRMTKLCGTRVPHSLMS
DLVPLRHDDSKVKDYGVDLAVEMIRKLTTDGDIRGVHLCTLNLEKSVTRVLEGLSWVGGS
LKPANRLIAMLQDASIGPDANLIITPHNATDSAAISLAAAGQGPDGEAGKGELNNAASWD
DFPNGRFGDFKSPAYGETDLWGSSIMSRNQALEQWGHPKTLDDLTTMFLRHLHSKIATTP
FSPTPLSPESLMIIQHLERLTRRGWWTVGSQPAINGASSSDEVVGWGPRGGYVYQKCFVE
FFLERADLERIERKIRDEGHGWVDYFAGNVQGECRTTVPEGGRNAVTWGVFPGQEIAQST
IIERESFLSWKDEAFSIWAEWASFYPPDSQERRLLESIRAERWLVSVVHHDYTDPSALWT
FLLKGDPVL
>A0A1X6N5W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Postia placenta MAD-698-R-SB12|TrEMBL
MKISQKIAQAEKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQKLIGIETCMHLTCTNMPKEKVDIALKEAKEHGCRNVLALRGDPPMGKDE
WEAVEGGFVHGIDLVQHIRTKYGDYFDIAVAGFPQHQLLTPDELALELKYLKEKIDGGAN
FIFTQMFYDVDIFIQWVHSVREAGITVPIVPGIAPIQTWNGFHKATSLAKTKIPQSFLDE
LEPHKNNDEKVREIGTRLVAEMCRRILNEPIGIKGLHFYTMNLEKATRMLLEELNLVPRI
QTVKPLPWRQSLTPNRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQTVEEALQLWDHPTSADEIGKLFAKFCQGQLPALPWSDSAPSSETTVIATQLF
KLNEIGFLTINSQPAVDGARSDDRIHGWGPSNGYVYQKAYLEFFVSPQLLDALLPHIERD
VNITYYVINKRGDLRTNTHSDGPNAVTWGVFPNKEIIQPTIVEAISFMAWKDEAYELGRQ
WAKYYEPESPSRKLIDNIMDTYYLVNVVHNDYKKPEAIFEPFFKAGAELAASQGSQPVLN
GH
>A0A1H9AGE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lewinella agarilytica|TrEMBL
MRVTDYFEQAKGKTLISFEVLPPLKGGSMQAIFDTLDPLMEFKPPFIDVTYHREEYVYKR
RPSGFYEKASIRKRPGTVGICAAIMHRYGVDAVPHLLCGGFTRQDTENALIDLGFLDVQN
VLALRGDARKFEGKFIPEKDGHDYASDLVEQISNMNKGIYLDDLTATDEASKTNFCIGVA
GYPEKHFESPNMEIDLRYVKKKIEAGANYIVTQMFFDNEKYFAYVDACRKAGIDVPIVPG
LKPLTKLYQLNSIPRLFHVDLPDDLVSAITAAKNGEARRQAGIEWCIAQSQELKERGAPC
LHYYTMGDSSTIQAIAKSVY
>A0A4T2APW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinifilum sp. JC120|TrEMBL
MQVAQNINEAGQFFSFEFFPPKDKSTWPVFMERAARLAALNPLFASVTYGAGGTSHDNSL
EICSLLKKDMGIDILAHLTCVGASEKSIDEFVGRLGEAGVSDILALGGDGVKDANGDGQS
RFMHASDLVEYVDEKFSGVGMAVAGYPGGHPESPSIVKDIEVHNSKLSKGADFTMTQLFF
DNRLYFDYVDRLAEIGSSAPVIPGVLPIQSLGSLRRIMSLCGAAIPGDLYCGVEKAFEKG
GDEAVMEFGFDFARKQITDLLDKGAPGVHIYSLNRAAMCERLITNLKSDGYFC
>A0A2I8EMI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia terrae|TrEMBL
MNPIELSFEFFPPKTQEGLDKLRATRAELLPLKPKFVSVTFGAGGSTQQGTLDTVLDMAK
DGLEAAPHLSCIGSSRESLRAILNEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFRIEVAGYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DAHKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VADLCRRLVEAKVPGLHFYTLNGAAATKAICERLAG
>A0A4Q5SBI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium|TrEMBL
MDTREDFTQRAAAVGSAPLFAALPGDIEVSFEFFPPKNETMAQTLRDSVDTLAPLGPRFV
SVTYGAGGTTRERTHAEVVRINNEVGIPAAAHLTCVQATREEVDAIARDYWANGIRHIVA
LRGDAPPGSGAYESHPGGYANAAELVAGLKRIADFEISVGAYPEVHPDSAATNSAALA
>A0A143WNB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tremblaya princeps|TrEMBL
MHGLSFEFFAPRSHAGSLRLLCAQQHLVRFAPKFVSVTRSASMGHRAHLDVVASTLRVFP
STAPHVLLCALPGDMSRELGAYARLGVRHLVLLMGDHRRTPVQKGAAELVSLVRRTYGDA
FYIDVAAYPDGHPMSATVYDDVRSLARKVRCGANSAITQCFYNPDAYCRLQDELYRLGIS
VPVTPGIMPTLSHAYMSRFILPSGVDVPSWILKRLDALRDCSASVIDFGEDVARALCDSL
AERGATDFHLYTLNDHQTVGRVCQHILGPASAG
>A0A1G3QH80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium RBG_13_51_14|TrEMBL
MAQSFKDILNSGKFVITSEIGPPKGSNIGTMLHHIDILKGRVDALNVTDHQSSVMRFPSI
GGALAIVERGGEAILQMTCRDRNRLALQAELLFAHTRGVRNVLCLTGDAVVVGDHKTAKG
VFDLDSSQLLRMIRLLESGKDMGGNDLDGGVAFCAGAIVTPEADPPGPQMIKFEKKIDAG
AEFFQTQAIYDLDNFRRFMDHARKFKVKVLAGIVLLTSAPMAKFMNKNVPGIVVPQPLID
ELAGAPKGEALRRGIEIAGRMIREIREKKLCDGAHIMAIGKEEVVPDILKAAGME
>A0A4Q3D6U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium|TrEMBL
MQATVRGAGKVCALIDRWSIEITAKDTARLEEAAALIPPGTKVPVTFLPGETMAARVATA
RRVKELGFVPVPHISARRLHSAEELRGFLAALQREVGTDHAFVVAGDPPTPMGPYPDALS
LIRSGMLAEYGIKRVGISGYPEGHADIGNDKIWQATRDKRDLLLRGGHDFAIVTQFGFNA
RPMLDWVEQVRGAGIDATIRLGIPGPASVKRLLSFAARCGVSASASVMAKYGLSVTRLLS
NAGPDRLIEELAARFDPARHGEVLLHFYPFGGLRATAEWVRDFQAKHGCGRGQG
>A0A0E3NY04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. MTP4|TrEMBL
MLFNFREKLNSSKFLVTAEISPPKGTNVAAPLEDASQLKGLADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEVIMQLTCRDRNRIGLQSDLLGAYALGLRNVCVMTGDFPSCGDHPGSKP
VYDLDSVQLLELVRKLDKGIDLAGNRLDGGTSFCMGAVSGINPQEVLQLIKLEKKVSCGA
DFIQTQAVYDVGMFEEFVESTAHLEVPILAGLIPLKSLRMAEYMNEHISGIHVPEEILSR
LKTASDPADEGFSIASETIKELTKLCRGVHIMPIGSHKNTRRLLSMAGISRK
>A0A7U9P6B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus thermopakistaniensis (strain MAS1)|TrEMBL
MGLLDKLKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIAAMAKALSDRTPVTEKTVKRRAVSVS
VQADRPAPSPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKEQLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACGGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A846E6K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO2B7|TrEMBL
MTTNFRRAVEAKEFLITAEVAPPKGSNPAHMVKMAQTLKGRVHAVNITDGSRAVLRMSSF
ASAVILSQHGIEPICQITCRDRNSIGLQADLMGADALGIHNILALTGDPVKAGDQKEAKP
VFELESVRLLKLISKLNSGFDANDKPLTDEATDLFAGGAVDPQLKSWSSLQKRFERKIEA
GAQFFQSQLITDFERLDKFMTEIASGTDKPILAGIFLLKSAKNAQFINRYVPGVHIPDEI
INRLAKAPKPLQEGMKIAAEQVKLAKEICQGVHMMAVKREDLIAPILDLAGIAPIK
>A0A847I969|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp|TrEMBL
MMGRVTDSISSGSDVLARAGQSVVERLSDPYSGPVPFSVEFFPPRDADAEARLWRAARTF
ERMNPAFVSMTYGAGGTTRDRTVRIAGELATETTLLTVAHLTAVNHSVDELRSLVGAYAD
RGITNLLALRGDPPGDPLGEWVKHPDGVQYAEELVELIRQLGDFHIGVASFPEGHHRSPS
LAADTENLVRKLRAGAEYSVTQVFFDVEDYFRLRDRLAATDAEQAAKPLIPGLMPITSLA
TARRMTELSGSKIPPAVEERLAKAAGDGPEENRADVRAVGIDLCTEMSERLIAEGAPCLH
FCSLNFVKATSEVLDRIGIDTRGALAGI
>A0A7K1TEG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter ginkgonis|TrEMBL
MKVTEHLRRADGKTLFSFEVLPPRKGENIHTLFSNIEPLMEFKPPFIDVTYHREEFVLRE
RPGGLLQRKAVRKRPGTVGICAAIKNRFDVDTVPHLICGGFAKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFQPHPDGHTYACDLIGQIAELNHGRYHDHDEQYQPAGAEPVLCTDF
CIGTAGYPEKHFEAPNHGSDIRFLKEKIDRGADYIVTQMFFDNEEFFKFEKRCRDAGITV
PIIPGLKPLTTKSQLTALPRAFFLSIPEALSEAIHQTKDNAAAREVGIEWCLNQSRELMA
HGVPCLHYYSMGKSEAIRRVAAGLF
>C2VGX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus Rock3-29|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTNRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQVALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIEKDTIQRPKVVH
THEKRSKVQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7Z2B298|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea vagans|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWTSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMSAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAAA
>A0A7L4C3J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nyctiprogne leucopyga|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEESNGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRSYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGVWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>Q1MYH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bermanella marisrubri|TrEMBL
MEHFRLSFEFFPTKTEEGTKKLYATRDKLAELKPDFFSVTFGAGGSTRDHTMDVVTKMNG
MGVGTAPHLSCIGQSKDEIKQLLSTYADNKVERIVALRGDLPSGMAVSSGELKYANELVE
LIKQEHGDQFHLEVAAYPEMHPQAPNFEADLENFKRKVEAGADSAITQYFFNPDSYFYYV
DRCMEMGIEIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVESIQKFGEE
VVTQMCEDLVENDVPGLHFYTLNQADPCINIWKNLGLW
>V0Z7R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 908573|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCISAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>G1WBL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella oulorum F0390|TrEMBL
MNVIDIIQQHKGHNNFSFEVLPPLKGYGTANLFATIDRLNMLHPLYVNITTHHSEYVYRA
LENGQFERNRVRRRPGTIAIAAAIQNKYQLPVVPHVICSGATAEQIEYELLDLQFLGIEN
LLLLRGDKAKDDRVFTPVPGGYCHTTELISQVNRFNNGQFLDGTSMKYPGHPFAYGVAAY
PEKHDEAPNIALDLQYLKAKQEAGAQYAVTQLFYDNSKFFTFVEQARAQGITLPIIPGIK
PFARLSQFTVVPKTFHCDLPEALAHEVLKCKTDEDAKQLGIAWGIEQCKELYAAGVSNIH
FYTVSAVESVYEIAKQLV
>A0A2N3HNH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Confluentibacter flavum|TrEMBL
MKVTDHIKKANGKTLFSFEVIPPQKGKNIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
KGNGLLDKRMTRMRPGTVGICASIMHKYGADAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VMALRGDSMKDEPYFKPVEGGNAFASELVEQIANLNRGKYLHDDVIVERHADFCIGVAGY
PEKHMEAPSLVTDLKRLKAKVDAGADYVVTQMFFDNNKFFEFVEKARAAGITVPIIPGIK
PIAVKRHLQLLPQVFKIDLPQELIDAVEACKDNNAVRQVGIEFAIQQSKELRDFGVPVLH
YYSMGKSDNIKAIASALF
>A0A552UF21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glacieibacterium frigidum|TrEMBL
MDASAIHPDWARPRPSVMTDGYSLEITAKDVDALIVAAPAVRPDTPVAITFLPGETMDAR
IAAAIKVRELGFEPMPHLSARRFASHDELVAIVERSTREAGVRRMFLVAGDPPVPVGPFA
DTMSLLRTGLFERHGITAIGIAGHPDGHPAMQGDALWIALDEKRREIAARGMATLIVTQF
GFDAAPLLAWLGELRARGIDAPVRIGVPGPAGIKTLIRYAAHCGVGASAAVMAKYGVSLT
RLLGTAGPDRLVDALAAGITPAHGAVRLHFYPFGGLARTVEWIVEHDRAAHRGAAT
>A0A659L6G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E2586|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4R6VNX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora succinea|TrEMBL
MDHVSPLAALLADPRYEVAPTAGVLDAAAAIPAGATVTVTAAPSRGLAATVDTAVALAAR
GYTAVPHLAARSVRDRGELAGHLDRLAAAGVREVFVVGGDAREPAGDLPDGLALLRAMED
LGRRPPRVGVPSYPDGHHRIADDVLWADLRVKQFHADYTVTQLCFDADLVCRFAGEARER
GIDLPVVAGVPGVVDAARLLRLSVRIGVADAVRFARSHRSTAGALLRPGRHTPDELVAGL
AAGGCDLAGLHLFTFNQIEPTVRWLSQARRTAA
>A0A101LHY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. EpS/L25|TrEMBL
MKPSLSFEFFPCKTEAGHEKLIATARQLAGHGPEFFSCTYGAGGSTRDGTYRTVRQLNDE
VGVPTAPHLSCVGDSKAKLRELLQQYREAGINRIVALRGDLPSGMGLSGGGELRHASDLV
TFIREETGDHFHIEVAAYPETHPQARSFTDDVRNFVYKMEAGADRAVTQYFFNADCYFHF
VERVRKLGVEAPVIPGIMPITNYSKLARFSDACGAELPRWLRKQLEAYGDDTQSIQAFGE
EVMTALCERLLEGGAPGVHFYTLNQAEPCIAIWRNLGF
>T0REQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteriovorax sp. Seq25_V|TrEMBL
MKVIEHISKSNGTLFSFEIVPPPRGKTITAVTDVVETLLPHNPSWIDVTAHPAGAYYNER
PDGTIERKIYKKRPGTIGICGVIQNRFRVDTVTHLLTQGFTKEETEDAMIELNFLGIHNV
LALRGDGLNYNKQYDKSRSVNHYAIDLVKQINDVKNGRFLDELSQSLPLDFGVGVAGYPE
KHFEAPSLKLDIQHLKDKVDAGADYIATQMFFKNEKYFQFVELCRQAGIQVPIVPGIKVI
KNLKQFNSVPSNFYVDFPDEFVEEAHANPKHVEEIGINFAIKQCEELVNAKVPSLHFYVM
NDAKSVAQVVKKFF
>A0A0P0YCZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asaia bogorensis NBRC 16594|TrEMBL
MMSSGTSPLGPVTPVMIPHLANDTQAARLEAIRTIRTLGLLPVPHFSARRLASKAACETL
LAQMVAEAEIERCFIVAGDPSEPAGPFADSAALLATGLFEKAGIRVVGIGGYPEGHPLMT
PEQGWTVLQHKCRDIEARGMTPEIVTQFGFDAQAIMAWLMRLRERGITCHVRIGVPGPAS
IASLLRFAARCGVGASASVLSRYGISLGKLLGSAGPDQLITQLEEQLADAHGPVSLHFYP
FGNLGRTMDWIG
>A0A2E6EGB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium|TrEMBL
MAFANAQYLEAINRNLQDIDGKVNVSFEFXPPKTAQMEQTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDATKQTLVXIAKDYWQNGIRHIVALRGD
LPPGSTEXPALYAADLVEILRSVADFDISVAAYPEIHPEAPNAQFDLLNLKRKVDAGASR
AITQFFFDTEKFLRYRDRCAAIGIDVDIIPGILPVTNFQQLQKFAALTNVAVPQWMHKAY
EGLENDAATRNLVGANIAMEMVKVLSREGISHFHFYTLNRSELSYAICHLLGVRPQIAV
>A0A1F9MD59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYD12_FULL_53_23|TrEMBL
MKSPFQQSLYNPEQFTITLELVPSRGGHNREHEHTLALAEKLAHDPRIQAVSITENAGGH
AALSPEVLGREIQKLGLDVIVHFSSKDKNRNQMESLLFAWDRRGIRDLLVITGDYPQEGY
QGFAKPVFDLGSVHVLDLISRMNRGNYGPNQGRGAISPTSFLMGVALSPFKRLEAELLMQ
YAKLHRKAEQGADYIITQVGYDARKFHEVLQYIKLNNLNLPVLGNVFVPNLTVAALMRTG
KIPGCIITEALYAEIRREATSLDKGKQARLLRAAKLLAILKGLGYAGAHLGGPGLTYDNI
DFILNTADSFADKWRELIPKMNYWHQDGFYLYKKDQATGLNTSETSVCAKRSTCLQTNYR
LARLVHNLAFTQEAPFYPLSKKICLVLEGSGFDNGLTHLEHVAKFLLFGCQNCGDCTLSE
LAFVCPQSGCAKYLLNGPCGGSRDGWCEVYPGKKRCLYVRIYERLVACDLPESMRKGFVP
PRNWALNNTSSWLNFFRGLDHAGEGRTSENGTEEKKKTNPK
>A0A3S0EWI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Melainabacteria bacterium|TrEMBL
MTHPFLQALKERPLLVDGATGTLLYSRGASTEASFEHLNLTRQDLVQQAHIDYINAGADV
IETNSFSGNRLRLANFGLEEQVWKLNVWAAKVARNAREVAGQPVFVAGSVGPTGKLLSPL
GDVTEEEIANAYQEQMEALLAGGVDLFMIETMSSLEETAIAVRMARKVSQLPVVAQLSFS
VEGHTFLGVTPEDAVRLLLELGDDLPDVFGINCGAGPGPVFDSLIRLSAAVRAKGYGEDK
ITFSCLPNAGQPSLSGGRYTFMSRPNYCASYVEPMVRSGARLIGGCCGTTPEHIKAMRAA
LDRYIQSSKQASSATLTDLPAVEVPPAVSIIAKSGKSDSSHSNNLKDGKEGKAKGELPDL
AMRLKEAKEKDNGDFYISVELDPPKGAVSKKLLQAAQLIYEAGADAINVGDSPMARVRMS
SLATCQLISQKVGIDTIIHFTTRDRNLMGIQADLLGCQALGIKNVIALTGDPPALGNYVH
ATAVYDVDSVGLIKIISQLNQGQDIAGNSIGSPTTLSIACALNPTHENRQQELERLRKKI
DAGAHFIMTQPIYQVTDLTDFLDQFGPLPIPILVGIMPLHSFKHAEYLHNEVPGISIPQE
IRDAMEKAGDEGSQVGLELAEKLLDEVKSLCQGTYLVPSFGRYEEMATLVRRLKAKSKSK
SAAPA
>A0A418YQR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium terrigena|TrEMBL
MTLNDPVAPLYADLAGDCHVSFEFFPPKTEKMEAQLWSAIETLTPLQPKFVSVTYGAGGS
TRERTHNTVARIARETPLAAAAHLTCVGASKAEIGEIADAYWDAGVRHIVALRGDPPEVG
GTFEPHPDGYKGAAELVEGLMQRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFTPDAYFRFLDKTLAAGITADIVPGIMPVSNFAATQRMAAMCNTQVPSWMGRLF
EGLDDHPASRQLVSATIAAELCRSLYGGGVRDFHFYTLNRAELSFAICHLLGLRANISLE
TAA
>A0A2T7TNV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Bz4|TrEMBL
MVDHPGGLPLRVEIIPGSGVVEALKEHLPPPAVVTITCLPHHGAEETVDLAVRLAGLGYQ
AVPHLAARSIASRGQLTGFLSRLQAAGVSDIFVIAGDGGSAAGPYAWSGALMEDIASIGG
GSFVLGAAAYPEGRPGASAGELTDLLLAKQELCSWAVTQLCFSGPVLAAYVAELRTAGIT
LPLWAGVPGAVGRARLISLAARIGVGPSLKFARRSLTGTGGGSLVRSVLAPSSYDPSPLV
RSVLDSGGFAGLHVYSFNNLAPISRIFTVG
>A0A429AED7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea sp. WAC 01424|TrEMBL
MPFELVCEIEPPTKPDLKRVRHQIGTLSQVAHSFLIPDNHIGRATVSSVAVAHEVEAMGG
RSIACLNSRDRNLLGFHRDLLTAAAYGVGRFLFVYGDKPASGNRTGDLTVRTMIEEARGF
SADFRVGAAAGLRPLPAWKRAADFLFSQVSFSVEAQVRWREANPVDVPVYAGVMVLASER
HARTLAAAIPDIALPADLVERVAADRMAGVEAACEQVFALRDSGAFDGVHLIPVTRYRDV
ESRLAGAL
>A0A3N9V213|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcus sp|TrEMBL
MESQKHYSRIYSMEFFPPRTSEAEAALVHTLDRLAPLKPRFCSVTFGAAGSTREKTFETV
CDIQQNRNLEAAPHISCIASTRTNIRDVLLAYKDNGIRHIVALRGDMPSGMMSAGEFRYA
NELVAFIREETGDHFHIEVAAYPEMHPQAHNLEADLKSFRRKVDAGANGAITQYFFNPEA
YFRFIDDCEKLGIDIPIVPGIMPITNYAQIARFSEMCGADIPRWMRKRLEGFGDNRQAIR
AFGLEVISDLCQRLLEQGAPGLHFYTLNQADAILGIWSNLGLEHESLEPVLI
>A0A3F3R4W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus niger|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDGQDPARDLPYL
IEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPHVLSKLEEVKHDDDAVKRIGVDIITDLVHGIRDLVSPGLRGFHFYTLNLEKT
VSFILERCELIPPYTEIDDSDALADGGNLSALDSSSYIAPNGAPIRTLASRRSSVSSIPH
NRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEEDSNGLNAETAIIQPELLTLIDKKGWWTLASQPAINGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNTDDPDPIDIN
PANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDDTK
NDVWLVCVVGQEFGAGTEPGSEEEEDEKKWMWRELANSQ
>A0A212BAH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. A46|TrEMBL
MSQDRRYSFEFFPAKTEAGHEKLLATARNLASCKPDFFSCTYGAGGSTRDRTLQTVLQLD
GEIQVPTAPHLSCVGDSKAELRALLAHYKDAGIQRIVALRGDLPSGMGMASGELRHANDL
VAFIRAETGDHFHIEVAAYPEVHPQARNFEEDLKHFVNKVNAGASSAITQYFFNADSYFY
FVERARRQGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVASIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLALWRNLKLPR
>A0A0S8BY47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium SG8_38|TrEMBL
MRIADLYAAQEGPVLSLEFFTPKDEAGRRALWRAIERLLAIEPGFVSITCGAAGTTRERT
ADLAIEIQQTFRIPTMAHLVCTGTTKSELDATLRHMRAHGIDNVLALRGDPPRGNAAWKP
VEGGFRYASELTGFVRTGYSLGIGGACYPEKHHEAPSLEADIRNLKRKVEAGAEFLITQL
FFDNDKYWSFVEAVRAEGIHVPIVPGIMPVLNLTNLHRIASLSPGTSVPDSLEAALRDAG
DDEEAALQAGVDFAAGQCRSLLSGGAPGLHFYTLNRSKATLRTVSQLQR
>A0A0S3F2R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium baderi|TrEMBL
MTLSFPSVEEARRALDAPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLGPKFV
SVTYGAGGSTRERTHNTVARIAKETPLAAAAHLTCVAASKDEITEVADAYWDAGVRHIVA
LRGDPPVAGAKFEPHPQGYQGAAELVDGLVKRHPFEISVAAYPETHPDAASAQGDLDNLK
RKLDAGATRAITQFFFEPDTFFRFRDTAAAAGISADIIPGIMPVSNFAAVQRMSAMCNTD
VPLWMGRLFEGLDTLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPEKSA
>A0A430S349|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus|TrEMBL
MKIRDLLKARKGPLFSFGFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRDRS
VLWAKRILDLGLNALAHLTVAGQSQEEVAGVLDRFVEAGVENILALRGDPPQGERVFRPH
PQGFRYAMELVAFIRSRYGEGVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFHNAHYFGFLERARRVGITIPILPGIMPITSYPQLRRFTEVCGASIPGPLLSRLERYQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNRSPATRRVLERLGFKPA
>A0A1Z8NEP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium TMED16|TrEMBL
MKVTDYIKNVNQTLFSFEILPPLKGKSIQSIYDGIDPLMEFNPKFVNVTYHREEYIYKEK
DNGLLEKVSIRKRPGTVGICAAIMNKYKVDAIPHLICGGFSKEETENALIDLQFLGIDNV
LALRGDPIKTENTFKAHPKGHQYASDLIHQVNDMNHGKYCIDDIKMAPTDFCIGAAGYPE
KHFEAMNLKTDLIHLKEKVDAGATYIVTQMFFDNKKYFDFVKACRNFGIDVPIIPGMKPI
KTLNHITFLPKFFHIDYPEELSSELLKCKTNAEVEKVGIEWGIEQSKELMKEGVPCIHYY
TMSNSDAVKAIANQIF
>A0A1F8R4M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_58_14|TrEMBL
MEPASRLQAALQRGEFVVTAEIVPPTGASASPVREQALRLQGLVHAANVTENPMATPHMS
SLACCALLAQHGIEPVLQLTGRDYNRVALQSEALGASALGIHNVLCLTGDPPTVGRRPAG
ELPFDLDATQMLWILRRLRDEGRFLDGRHVSEAPRYFLGAAGSPNDPDPAHEALRLEKKI
NAGAQFIQTQLIFDVATFQRWLQALDKRGLLTRVHILAGIGLLHSVKTARFLNERIPGVF
VPPHLIQRLEQSPSHEETGLEIALELIQQVKALPEVSGIHIMSLGQESILPRLLEQVELG
TWA
>A0A2S8ZPV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. MYb7|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHPSAMDLVNQINNLGRGKYLHNEEQACDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREIGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A386URX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus yeei|TrEMBL
MTTPALSFEFFPPKTLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETMQIVADYAAAGVHEIVALRGDAPQGQERFAPHPQGFANSV
ELIEAIAARGDMTIRCGAYPEPHPESPDTAADVAWLKRKTDAGATSAITQFFFDAETFFR
FRDQCERAGITARIIPGILPIQSWAGTRRFAERCGTSVPAWAEDAFAAAGKAGEAQLALE
TCVQLCSDLVAGGVDSLHFYTLNKPDLVQKVCAALGVVPPRGAMSDVA
>A0A1H4E744|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrimonas cliftonensis|TrEMBL
MKGAAQDAPNRAGSLADLVRPYPEPPAGHVSDSRLEAVLRSGRFAVTAELNPPDSADPAD
VFEAARPLAEVADAINATDASGANCHMSSIGICALLTRAGHGTVYQISCRDRNRIAIQGD
VLGAAAMGVRNVLCLTGDGVGAGDQPGARPVFDFDSVSLVRAIRTMRDDGVFLSGRRITR
PPRLFIGAAENPCAEPRDWRPERLAKKVEAGADFIQTNYIFDLPVFEAFMARVRDLGLDR
RVFILAGVGPLASARAARWMRSNVPGVHIPDAVIDRLERAANPAEEGKRLCIELIGRMRE
IHGVAGVHVMAYRREHLVSEIVHASGALDGRRPWLRHPDA
>A0A2M7EDZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium CG01_land_8_20_14_3_00_44_22|TrEMBL
MSFKDILNSGKFAVTAEAGPPKGTDIKDMLHHMELLKGKVDAVNVTDNQSAVMRICSMAV
SKIAMEHGLEPIFQMTCRDRNRIGLQSDLLGANILGIKNVLCMTGDHVSAGDHKGAKPVY
DVESVQLLKIVDGLNNGKDMSGNELKGSTDFFQGAVVTPEANPIEPQLIKFEKKIRAGAK
FFQTQAIYDIEKFRDFMKHARKFPVKILAGFVVLKSAGMANFLNNNVPGIRVPQALIDEL
KAAGKEKALDTGMNITARHIKQLKEEKICDGVHIMAIGMEDKVPEIMERAGLL
>A0A151GR12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drechmeria coniospora|TrEMBL
MHIKEILSEAEKGAQPSFSFEYFPPKTSQGVQNLYERMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVTQAQSVSGLETCMHLTCTDMGLDRVNEALARAYQAGCTNILALRGDPPRDQEK
WTATDGGFQYARDLVRHIRDTYGNHFDIGVAGYPEGCDDNKDEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWAARVRDRGITIPILPGIMPIATYASFLRRANHMQCRVPPEWLERL
EPVKNDDVAVRELGKSLVADMCRKLLANGIHHLHFYTMNLAQATRMLLEELEWAPCAERP
LHPALPWKQSKALGRRDEDVRPIFWRKRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNQGKWGVPKKLRDIADTFVRYLNQEIDSLPWSESPLTGEADAIRRDLIA
LNQRGLLTINSQPAVDGVKSSHPIHGWGPSNGYVYQKAYLELLVPPSIVDQMLSRIGSNS
SLSYYAVTKNGELKSNAASDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
AHCFDPDTPSRTLIETIMDEWYLVNIVNNDFHDNQTIFELFKDLEVKEADIISLS
>A0A4Y5W9H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas psychrotolerans|TrEMBL
MKPSLSFEFFPCKTEAGHEKLIATARELASHGPEFFSCTYGAGGSTRDGTYRTVRQLNDE
VGVPTAPHLSCVGDSKAKLRELLQQYREAGINRIVALRGDLPSGMGLSGGGELRHASDLV
AFIREETGDHFHIEVAAYPETHPQARSFTDDVRNFVYKMQAGADRAVTQYFFNADCYFHF
VERVRKLGVEAPVIPGIMPITNYSKLARFSDACGAELPRWLRKQLEAYGDDTQSIQAFGE
EVMTALCERLLEGGAPGVHFYTLNQAEPCIAIWRNLGF
>A0A1N6KT04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Singulisphaera sp. GP187|TrEMBL
MHILDIFKAHPTTFSFEFFPPKTDKSSSDLFRNIEQLQVLQPSFVSVTYGAGGSTRERTH
DLVIRIQSETNLTAVSHLTCVCHGMDDLASILDRYASSGIENILALGGDPPRNLVDYNRG
NDAFQHAAGLVAFIKSRTSQAHPRGFGIGVAGFPEGHPSTPNRLSEMDHLKRKVDAGADY
ICTQLFFSNADFYDFRERCEYAGIKVPILAGIMPITRDTNISRMAELALGARFPARLLKS
LDRCGDDPEARERVGIHWATEQCRDLLDNNVRGLHFYTLNRSDATRRIYENLGVKDSVGL
RQA
>A0A848RQ80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobiluncus mulieris|TrEMBL
MASRVDWVAPDAGGVLDAPGTPVAFTSVSRGANPKSSRNPTRPVRVSFELYPPRNPDPFS
QAWAGIDRLLDAHPDYVSVTFGTSNSTSASSQSVLAHALQRLGRPVLAHLTCVGKTRTEL
STTITEMLDIGVRDFLALRGDNPKGSVNWEPAPGEFSRASQLVTLLREVAAEYLGDARAI
SIAVAAYPAGTVSARTNAVAALAEKQSAGADFAITQVFYNADDYGALLDSATYQGVSIPI
IPGIIPFTDAARLQRLEGLTGVSVPSRLQAISEISDPEERFLEGLSATLDFVNDLIQAGA
PGLHFYTFNRPRPVLDLVEHLRSRGFTHVDEDSSSELLDLMNAAMQRFSP
>A0A1A8PU15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius pienaari|TrEMBL
MNVAAPFTVMVNQVQRVDGSWLSCKSDSSGTSNSGGESSKESSRCSTPVLDAVRSDRLRD
KMRRRMESGDQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKET
SSMMIASTAVNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEE
EEGGFNYAVDLVKHIRSEFDDYFDVCVAGYPTGHPEAESYADDLRHLKEKVDAGADFIIT
QLFFRADTFLTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPI
KDNDAAIRNYGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPL
PWAV
>A0A821FS95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MEFTLGDNQTVPGDCKMHAHETHLESIHNLNRLKRIESEGANIAGKICSLQSAKYVSLTE
KISKRIADNDRWFSLEFFPPRTPSGAANLIGCFDRMAAGRPLFCDITWHPAGDPAGDKET
SSMMIANTMLNYCGIDTMLHITCYGAKKAAMLEYLYKAKDCGIRSLLALRGDPHVGEEWN
PAKSDFRYALDLVKFIRQHFGDYFVICVAGYPQGHPDSTSYEDDLDYLKEKIDCGADFII
TQLFFQAETFIKFESDCRSIGIKCPIIPGILPIQGYASLRNIVRLAKLDVPKEILACIEP
IKDNDEAIRNFGVQACLDLCCALLDSGKVNGLHFYTLNREFATIEILKXLGLWLDEQSLR
ALPWKKTSFSHARSQENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGISSAPSFGVLTDYH
LFYMKIDATRDELLDEWGRELTCEQDVWKMFACYIGGEKNSIDKVVRRFPWTDEELSAET
TLIQKNLVEFNKRGILTINSQPAVNGKSSSDPVVGWGTPNGYVYQKAYLEFFTSAENIPA
LRSVLKTFPGVNYHFVNKSGEANETNTDDEQPIAVTWGVFAGKEIVQPTVVDPVSFMIWK
DEAFSLWTERWGKLYEPESRSHAIIEKIANTYFLVNLVDNDYPQGSCLWTILDSMFEYQK
LPKKNVES
>A0A1I0FCR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] cocleatum|TrEMBL
MKIIDLLHQRPTLSFEIFPPKNHDGDISSIYNTIDELAKLKPDFISVTYGAGGSTTENTV
EIASKIKNDYNIEAVAHLSCIDATPKQLTRIINSLKTNNIENILALRGDYPKGYDPVNAP
HYYKYASELNEFISKNYPDTFCLSGACYPEVHQDAVSLEEDLQALKKKVDAGAEYLITQI
FFDNNYYYRLVREARIRGINVPIIAGIMPATNSKSLLNIAKLSGCNIPYNLSAMIERFKN
NPYAMKEVGLNYATYQIIDLITNGVDGIHLYTMNKPEIAKEILLRTNNIFAEFIND
>A0A426G2I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIQTLDQMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVYQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARTIHQATHSLFKHYS
>A0A0U5CN66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus calidoustus|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMLGEDDSNKDFTFAVDLVRYIRKKYGDYFCLGVAAYPEGHPADSFQDVQDPKVDLPWL
VEKTQAGADFIMTQLTYDIDAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVKIPPRILAKLEEVKHDDDSVKRLGVDIIAELVDGIRNLPTSGFRGFHFYTLNLEKT
VSFILERCKLIPDYPDEEAVAVTEDVSFLTVEAAKKATSRRRASSISSIPHNRVIVDKIS
EPGSRDSMTHEATAASAGMPAQPPDRNTTLQISEGLGALGREATWDDFPNGRWGDARSPA
FGEIDGYGPSLHVAPSVAHRIWGYPVTPSDISTLFRRHVSGDLYMVPWSEGGAEENTSGL
NAETETIRPELLKLIDGKGWWTLASQPAVNGVRSDDPIFGWGPPGEGFVFQKPFVEFFCP
TSDFTNTLKPTLQKHGHEKLAWFAVNARGDFESSLPAQTADADPIEMNPNNVNAVTWGVF
RGKEIITPTIIEEVSFRAWGDEAYRIWDEWRRIYPRNSATERFLEETKNDVWLVCVVAQD
FGAGTENGSKEEEEEKKWMWRVLAEC
>I3DBP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella bettyae CCUG 2042|TrEMBL
MSYAKEINTLNQCISELNGNINVSFEFFPPKNAEMETLLWNSIHRLKTLSPKFVSVTYGA
NSGERERTHQVVKSIKQQAGIEAAPHLTGIDASPEQLKEIAQDYWNNGIRHIVALRGDEP
SGYQKKSFYAADLVALLRSVADFDISVAAYPEVHPDAKSAQADLINLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVTIGIDAEIVPGILPVTNFKQLGKMAKSTNVRIPHWLAKMYEGL
DNDPATRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHTLGVRPH
>A0A4V0EGW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVQSVLHSLDEIGVHQILALRGDIIEGLLPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FREKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNVKTARTIHQATHSLFKHYS
>A0A258YXM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium 16-61-112|TrEMBL
MSQRTFSFEFFPPKTAEGAEKLRATRAQLAQLKPKFFSVTFGAGGSTRDRTLETVREIQA
SGSEAAPHLSCIGSTQDNIREILNEYKSQGIRHLVALRGDLPSGTMDAGEFNYANELVSF
IRAETGDWFEIEVAAYPEIHPQARSWTDDLANFKRKVDAGADSAITQYFFNADAYFRFVD
EARALGVAIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLASIRAFGLDV
ITDQCERLLAGGAPGLHFYTMNQAGPSTTIWQRLGL
>A0A2G8MC72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium frigidaeris|TrEMBL
MRVSFEFFPPKTPEMDTTLWSSIERLAPLGPSFVSVTYGAGGSTRERTHNTVSRLVRETD
LKPAAHLTCVAATKGEVDDVVRAYHEAGVRHIVALRGDPAEGVGTAYTAHPGGYERSCDL
VAGIKRIGDFEVSVSAYPERHPEAGSLDQDLDALKAKVECGADRAITQFFFDNDLFFRYL
DRVQSRGIDIPIIPGILPVQNFKQAANFARRTGASVPDWLAARFEGLEDDVATRKLVAAA
VAAEQVLDLVDRGITDFHFYTMNRADLVYAICHLLGLRAAPAAAEKVAA
>K1VJG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichosporon asahii var. asahii (strain CBS 8904)|TrEMBL
MKITDKLAKAEREGRPFWSFEYFPPRTAQGLQNLYDRIERMRNLGPEFIDITWGAGGKNA
DLTSSLVQVCQETIGIETCMHLTCTEMPKEKVEWALAQAKQFGCQNILALRGDPPAGSST
WKPTPGGFVHAVDLVKYIHKEYPGDFCVAVAGFPDGHPETPPTPEGHHQEMLWLKEKVDA
GADFIFTQMFYDVDILFNWVKEVRSYGITVPIVPGIMPIQNWQKFQTWVQRENIKVPEHW
YEALNPVKGDDEQVRAVGTKLVGEMCRAILANEECGIKGLHVYTLNLEKGARMLLEELGM
NPNREQVAPLPWRPSLAANRRQESIRPIFWANRVESYLSRTSDWDEFPNGRWGDSRSPAY
GDLDGYPVAINVQPADAENLWGQPKSEADVRELFARFCRGELKKLPWSSQPPASETSIIS
ENLIKMNERGYLTINSQPAVDGAPSDDKVHGWGPAGGYVYQKAYLEFFVRPELLSQLIKR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGNQWANLYPEGSESNKLIHKIMDESYLVNIVANDFKDGLAIFEPFLLDQPVEA
>A0A0K2LVY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabaena sp. WA102|TrEMBL
MPDTYSFSAFNNFRTAAQRGDFLITAEVAPPKGGDPIHTIEMAATLKGRVHAVNITDGSR
AVMRMSSLVASVILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPQAKAVFDLEAVRLLQLIRNMNQGFDFNEKPLTDGALDLFAGAAVDPQSKSWSGLQS
RFEKKIAAGAQFFQSQLITDFEILEKFMNKIACGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEEGMKIAAEQVQTARGLCQGVHLMAVKREDLIAPILDLAGV
GKVS
>A0A3A9C0C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium D16-54|TrEMBL
MKIREILSKGEPTLSFEVFPPKTEDKYESVEHAVLEIARLKPAFMSVTYGAGGGTSRYTV
DIAATVQAQGVTPLAHLTCVSSTREKVVSVLEELKARGIENVLALRGDIPVGGQVEKDFH
YASELIREIRKIGDFCIGAACYPEGHVESVDKAQDIQHLKEKVEAGCDFVTTQMFFDNNI
LYNYLYRVREAGVTVPVIAGIMPVTNKAQIKRICSMSGTYLPARFKAIVDRFGDNPAAMK
QAGIAYAAEQIIDLIANGVNGIHIYSMNKPDVAARIQESLSEILC
>A0A5C4TEX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus hemerocallicola|TrEMBL
MKAGLRETLGERVLVGDGAMGTFLYQLGFPVGVSYEEYNLLKPDVIADVHKQYYDAGARL
FETNTFSANREKLSKFGLENEVSAINKAGVAIARQAVGDDAYIVGAVGSIRAARRRNITT
EQLVRNFQEQIEALLEGGADGLLLETFYDLEEMLIALRVARQLTELPVIGQFATDGGTTT
NDGVGYQEAFEQLKAEGADILGFNCHSGPNGILRTMEKLKPVDGLPLSVFPNAGLPGYVD
GKYVFGSKPDYVAENALKFADLGARLIGGCCGTTPEHIAAMVKALQGYTPRTDRPAADGG
EAGSVQPGPAIAVIEAEKSAEAAEPSLIELVKQRHTVIVEWDTPRDLDIGKFMEGAKALQ
EAGVDSITMADNALAVTRMSNLPMGFLLKERLGARPLLHIACRDRNLIGTQSHLMGMHAI
GLDHTLVITGDPSRFGDLPGSSSVYDMTSFEMIRLIKQLNEGIAFSGKPLKHKAKFIVAA
AFNPNVKYLDKAVQRLEKKIEAGADFIMTQPVYDAKLIENVYESTKHLNVPIFIGLMPIV
SEGNATFLHNEVPGIQLSEEVRKRMSGLSGEKGREMGVQIGKELLDAAMPKFNGIYIMTP
MHFYDMSVQLTRYVWGKTGKMPS
>A0A848V964|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia sp|TrEMBL
VAAYPEVHPEAPNAEFDLDNLKRKLDAGANRAITQFFFDVDRYLRFRERCAVAGIDSQLV
PGILPITRFPQLQRFAEQCGATVPEWLHERFAGLEDDAETRQMIAASVAIEQVRLLKQEG
IEEFHFYTLNRSELTFAICHALGVRPQQAAA
>A0A6Z2PIF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDCSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPDIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEIFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDAEPGERLLDKVKEGLTILVELDPPRTFDTTKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKAKIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A6G7Y836|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevilactibacter coleopterorum|TrEMBL
MPFPSIAERLAQRDAPTFSFEYFPPADDAGIQQLIGTVDQLSPLRPDWVSVTYGATGASR
YRTFSAVGAIRGQTAARTMGHLTVAGQDEGEIRRAIEAYERLGVTQILALRGDPPGGGAY
EPRSDGLATATDLVRLIRSMGDFSVGVAAFPAGHPESDLDLDARILLDKQEAGAEFAVTQ
LFFDAEAYFALVERFRALGGTIPIVAGIMPVTVPSQIERFATMSGARMPAAFEAKLRAVA
DDRDRFRAVGLELMTALCDDVLAGGAPGLQFFTLNRSKATQEILARLREMPARVPA
>A0A7W4YJH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia aquatica|TrEMBL
MSCTTARYSFELYPPRNERAAAALPATIDRLAAARPDFISVTYGANGSSRTSSLDVLRHI
LERTDVSPMAHLTCVGSSHEEANRLIREFLDAGVRRFLAVRGDPPEGAAPGEDGIGDIRS
SAELVQLIHRVQAERVPYGELTVPGLPAQAVLTRREHVQIAVAAFPNGHPASHSISQDID
ALLAKQAAGANLGITQLFFHAEDYLSFAQKAKDAGVAFPILPGIMPVTSPARLSRMLELS
GEDLPSDLAIQLEVEPTDEGRREIGIEWAAGLGRRLLDGGAPGLHLYTFNQSEAVLSVLD
RIGVLPAPDSISSATEREPA
>D4S4M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas noxia ATCC 43541|TrEMBL
MAQNSADIREHIKKEPLVFDGGMGTYYAQKTHTHGKGVELANIETPAVVGAIHTEYLQAG
AQAIKTNTFAANRIVYQGDESLVRRIIRAGWEIAARAAEPFGAYVFADIGPVTGLPHTDI
IAEYRFLADTFLACGATHFLFETNASIEGLIETAAHIKRICPHAFILASFSALPGGYTRD
GRFAEDLIHEAAESGSIDAVGFNCVNGVRQMRELGHHLGMTSLPLSLMPNAGHPIVVDGR
TFYESAPEYFGTSLAAIVRDGISIVGGCCGTTPEHIRALCAALADGTGEIDEEGEETRVQ
PMEVPLSPFFDALKSGGKPIAVELDPPETGNADKFLVGVRELQAAGISAITIADNPIARA
RMDAAMLAGRVHRELGIEPIPHMTCRDRNLNAIKSILLGLSAEGVHNMIAITGDPIPTAE
RDEVKSVYQFNSRKLASFVTSLGSRGDIVPFHVFGALNVNAKHFPSQLGLARKKMEAGMT
GFFTQPVLSERAKENLQTARDMLPGAFILGGIMPVVSERNARFMESEIVGIHVEERIISA
YRGLDRTAAEELAVRLSLAIAKDIEPYIDGYYIITPFSRTALIARIVEGIKERGEIR
>A0A849GDT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia sp|TrEMBL
MIENKKSNSDGSPRVSFEFFPPNSEKMDQTLWESIKRLAVLTPDFVSVTYGADGSTRERT
HQAVARILSDTELTAAPHLTCIGASRDEIDAIAREYWDMGVRHLVALRGDPPKDVTDYQP
RSDGYAYASDLVAGLKRVADFDVSVAAYPEVHPEAPNAEFDLDNLKRKLDAGANRAITQF
FFDVDRYLRFRERCAVAGIDSQLVPGILPITRFPQLQRFAEQCGATVPDWLHERFAGLED
DAETRQMIAASVAIEQVRLLKQEGIEEFHFYTLNRSELTFAICHALGVRPQQAAA
>A0A5M3A0C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKMPDALEELIAFGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEIFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDAEQGERLLDKVKEGLTILVELDPPRTFDTTKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKAKIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A6H2C3Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dolichospermum flos-aquae CCAP 1403/13F|TrEMBL
MQDTHSFSAFNNFRKAALAGEFLITAEVAPPKGGDPVQMLAMAATLKGRVHAVNITDGSR
AVMRMSSLVASVILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPQAKAVFDLEAVRLLQLIRNMNQGFDFNEKPLTDGALDLFAGAAVDPQSQSWSGLQS
RFEKKIVAGAQFFQSQLITDFEILEKFMDKIAVGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEEGMKIAAEQVQIARGLCQGVHLMAVKREDLIAPILDLAGV
EKVS
>A0A6J4MJG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Nocardioidaceae bacterium|TrEMBL
MRNKAEAAALRGLVETARYEVLPTPTIEDKILEHLPTDRMLTVTASPAKGLEATLDLTER
LAKQGYAVMPHLAARMVRDKSELAEVSDRLVAAGITAVFVPAGDKTPPEGEYDAALPLLA
DLTALGSPFAEVGITGYPETHPLISDDVTVQSMWDKRAHATQIVSNLVFDPAAVDRWLTR
MRSRGVGLPVWLGIPGPAERAKLLTMATKIGVGDSTRFLMKHKGALFRLAAPGGFTGERF
LENSAPVLARPESQVAGLHVFTFNQVAETEQWRQQLLDKLVSGR
>A0A2E6EAG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia sp|TrEMBL
MTFKDSLKTKDFVVTAHLNMADVSDPSTLLKQAAILKSAVDGVQVTDSIQEPIGAIATAA
LLIQQGIDPIVHMNCRDRNRIALEKDFMGATALGVTSVLIRRGTKILKSPKVGIKNVFDT
TALEFMAYINSLKEDTNSSVVSDFHIGANAEIFEPDLNWVPKNLIRKCEAGSNFIQLQIC
FDMEVLRKYMSQIVASKLTHSVNFIVSLSPLPSADVARWMRDNIKGALVPDFVIERMDQA
SNPESEGVTICAEMLRESRTIPGISGANLLTMGKLEDIPAAIDASGVRTN
>A0A0N6ZPK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CCM_MD2014|TrEMBL
MRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVRE
TEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPTADWIAHP
EGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFF
QPESYLRLRDRVAAAGCRTPVIPEVMPVTSVKMLERLPKLSNASFPAELKERILAVKDDP
AAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPRA
>A0A2E6E8M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia sp|TrEMBL
MKTFRQAVQGQAATVTAELTLQNHSDADDVARQVDLLAPWVDAIQVTDNAWSDMHISATV
AAALVLRHDVDPVAVLTCRDRNRIALCGDMLGLRALGVTSVLLLRGLEIPENHPDETNMV
FDISSRELVAMAAGLGNLDPPVPDKDFFIGIGARVLRPASGWAAKSLEERSSAGARFLQT
QLCFNLDILREYMQCLIAKQLTWKYSVIVSLAPLPSADKARWLKKNLSGSRIPSAVIRRL
EKAKDPEREGIEICAELMTEIVQIPGVTGINLMTMGNPESIRDAIKTSGLRQ
>A0A2V1K7Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corticimicrobacter populi|TrEMBL
MTDAYSLEVNAKDMPALTAAAPRIAPASIVSIPYLPGQDNDTRLAAARAVHKLGFDAMPH
LSARRVTSLTELDLFIKRATIEAGVEHCLIVAGDPPSPMGPFPDSLSLIETGIFERSGIK
VIGVSGHPEGHPVMDPAHRWDALEKKCHSIAMRGMTPLIVTQFSFDADSVLTWLKALRER
GLDHPVRIGVPGPAGIAVLMRYAALCGVSACTSIWSKYGFSMGKLLGTAGPDLFVDRLAA
GLTEAHGKVNLHFFPFGGIAQSAGWIEQYRSRRGKTAP
>A0A1Q6PYB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. CAG:74_58_120|TrEMBL
MRIASILNEKEITLSCEVFPPKHFDGIAQASAVAQEIAGLHPSFMSVTYGAAGSTPGHTI
AVAKAVAETGVTPLCHLTCVQSTREHVQHVLADMKTAGMENVLALRGDLPKEGEPCHDFA
YAAELIDFIHRQGDFCVGAACYPEGHPESGSRAKDMDYLRRKVDAGVDFLTTQMFFDNGL
LYNFLYRMQRAGMDIPVCAGIMPICDARQVARVVKLSGSIMPPRFAAIADRFAGDPQAMT
QAGIAFATEQIVDLVANGVGHIHLYTMNKPWIARAIVENLSSIIKLGE
>A0A2W6NMM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter valdiviensis|TrEMBL
MNKIENFIEILKSKEKCYTYEFSVPISFDLEEHFTLLKKSKILDVIDAFVCTDSPLAKLK
HNSLLASLKLQNHFNIPSITTMAMRDKNTLALQSELIGMNSLDLRLVLALTGDPLRHGNQ
IQARPVFEGNSQLLLKIISQLNSKKDINGKEIFGENKPIYAFSVLNAYANNKDNLYKKMY
EKIKNGANAIFTQPVYDLQNAKELLEFINSINKELNKNCMLVFGFFPITTYKTALFLHNK
LPGVFVPQDWLIELKEAQNTYNEEKIGIQKSKKLFKDLMKLHPKIHIMSANKLEIIEKIL
GELCYN
>A0A851AS79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Picathartes gymnocephalus|TrEMBL
MVNETQHSCSASSSSRSDGNSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVFAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVQGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A098M2Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus wynnii|TrEMBL
MKPDLRSAWGKTVLVGDGAMGTYLYQKGFPVGISYEELNLTSPGVIEDVHRSYIEAGAVL
LESNTFSANYDKLSKYGLESKVEEINRAGVRIARRAAGANGYVVGAVGSIRAGKRANLSA
AELKKYFGQQIVALLEEDVDGIMLETFYDVEELHLALRVVRNHSKLPVICQLAVDETART
LDGLSLPEAFRILEDDGADIIGFNCRTGPNGIKRALKHLQGSLVLPVSVYPNAGVADYVD
GEYKYGASPEYFGEMALTFADMGSRIIGGCCGTTPQHIAEIANALQGYIPQPLPAPTSRV
VERVQIQEHFGDDTGKSGGEPTLVDLAKERHTVIVELDPPRDLDIAKFMKGAEALRRAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGIDH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKANFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDCELIANIAKATAHLDIPVFIGVMPLASGRN
AEYLHNEVPGIQLSDEVRLRMKGLEGEEGRAEGVTIAKELLDAATEHFNGIYLMTPFMFY
DMSVQLLEYVWEKSGRKLSPLFR
>A0A317F0J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter paludis|TrEMBL
MKITDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADHSFIPTKGGHCYATDLIQHIKNHNDGKFLHEDIETFKSDFCIGVAGYP
EKHFEAPNLNADFKYLKQKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPDELTDALSHAKNNAEAKEIGTEAMIKQCKELMDFGAPVLHF
YTMGRPEQTKKIAKAIF
>A0A3G6U114|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium bernardetii|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAIAQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A0U3KAS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces globisporus C-1027|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKA
TQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPESLKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A1H8N975|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas aquamarina|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAARNPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRDETGDHFDIAVAAYPESHPQAPSLDKDVENFARKMNAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GTDVVTRLCERLLDGGAPGLHFYTLNQATPVLKVVDNLS
>A0A415WGD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. AM18-35|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTSSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>A0A4R4Q012|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. 15K316|TrEMBL
MRGWQPHPREHHARGLGPLRVAGFPAFSFEFFPPKTPEGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVPHPEGVLYAEELVQLIRGAGDFSVGVAAFPYKHPRSPDVTSDTEYFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTRMATIERSVQLSGAPF
PPALAERFARVADDAEAVRRLGVEQASEMCGRLLDEGVPGIHFITLNRSTATREVWQNLR
VQART
>A0A2S6UL56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha3_Bin4|TrEMBL
MISRLKTVLEGGHFVVTAETSPPDAADADAVLAQASCLKGVVDAVNVTDGAGARAHMSNL
ACAAILARDGIEPVLQFTTRDRNRLALQSDLIGTAALGIPNILCLHGDEVDVGDHPEAAP
VHDIDSRALITTARRMRDEGCFESGRIIDPPPKLFIGAADMPREPGPNFDPSGVTTKIDA
GADFFQTQFVFDVNALKRYMARLCDAGVPERANYIVGLGPLASAKSARWMNDNLFGVHVP
EPMIERLEGARDEKAEGREICLELLQKVTEIKGIHGAHLMGPRQEQTIAEIVASSGIVSG
RSGTG
>A0A3N9XK88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora arida|TrEMBL
MALGLPSTLPNPQPAIGELIREHQPTFSFEFFPPKTEAGEQLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVVGRLAGVGVRNVLAVR
GDPPGNPGGEWIRHPEGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAQFVR
KCRAGAEFAVTQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQFSTIERSVQLSGAPF
PPALAARFERVADNPDAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARV
>M1UV51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium callunae DSM 20147|TrEMBL
MQSSNIPASSQWAISDVLKRPSPGRVPFSVEFMPPRDDAAEGRLYRAAEVFHDLGASFVS
VTYGAGGSTRERTSRIARRLSRQPLTTLVHLTLVNHTRAEMEQILQEYSELGLTNLLALR
GDPPGDPLGEWQSTPGGLNYANELIELIKQSPEFQHFDVGIASFPEGHFRARTLEEDTEF
TLAKLRAGAEYSITQMFFDVEDYLRLRDRLVAADPVHGAKPIIPGLMPITSLRSVRRQVE
LSGAQLPRELEERLLAAANGDEEANKDEIRKVGIEYTTQMAERLIAEGAVDLHFMTLNFT
RATQEVLHNLGMAPAWGAEHGQDAVR
>A0A1M5K526|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. OV279|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIEN
IMALRGDAMKGHQYFEPTPGGHPSAMDLVHQINDLGRGKYLHNDEEACDELNKFCVGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVTKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEELINEVEKAKNNEAVKQIGVEWAINQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A1R1DDE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL H8-0548|TrEMBL
MKPDLREAFKQRILTGDGAMGTYLYQMGFPVGVSYEEFNMIRPDIIENIHLSYYDAGARV
IETNTFSANLEKLSKYGLEDEMDAINRAGVRVARAAIGKDAYVVGAVGSIRDGKLKNLRT
AKVIDAYQRQMHALLDEGVDGLLLETFYDLDEMLLALRIARASSNVPVICQFAVEDVGRA
QTGNGMKSAFDQLQAEGADIVGFNCRSGPNGIIRAIDAIEGSIELPLSVYPNAGIPDYID
GKYAYSAGPEYFAESAQRFADRGARLIGGCCGTTPAHIKAIAEALDGYIPQTIPTTTVVA
ATEQIVIKRPESQEKPLDASVQKQVIQEPSIVDLVKQRHTVIVELDPPRDLDIRKFMDGA
AALKEAKADAVTMADNSLAVTRMSNIALAALIQEKVGIRPLVHIACRDRNLIGTQSHMMG
LDALDIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNDGTAFSGKPLKQKAKF
VVGAAFNPNVKHLDKAVQRLERKITSGADYIMTQPVYDPSLIERIAEATKHLSVPVFIGI
MPLASGRNAEYLHNEVPGIQLSDEVRQRMAGLEGEAGRAEGIQIAKELLDAALPHFNGIY
LITPFMFYDMGVQLTQYVWDKTGRM
>A0A3M9L8B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus portucalensis FDF-1|TrEMBL
MPSAFKEKLLSDEFIVTSEISPPKGVDASSAFEEAGLVRDYVDAFNVTDNQRAVMRMSPL
AMGHLLKEQGLDIIMQFTCRDRNRLALQSDLLGAYAMGMENVCIMSGDYPTKGDNPGAKP
VYDLDSVQLLGAMNRLEEGFDIAGNPLESVPSFTKGAVCNTEPDQPLQLMKLEKKARMGI
DFFQTQAVYDIGHFETFMESISHIEVPVLAGLIPLKSAHMARFMNEKIPGIRVDDELIAR
MESSTDPAEEGLLICAEQIRELKKVCRGIHLMPIGHYRHITDLFEMAGLHEKN
>X1K5M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSLQPLFDKGKFVITAEVGPLKGTDTTELMEAVEILKGKVDAANVTDQQSSVMRLGSLAV
CHLLKMKGLEPVFQVTCRDRN
>A0A0F9SNS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MTGELGPPKGADANVVLDKAALLKGEVDAVNITDCQTAIVRMSSIAASQLVKSRGVEPVV
QMTCRDRNRIGIQSDLLGAWALGMKNLLCLTGDHQKFGNHPESKNVFDMDSIQLVQAVRD
MRDKKQFINGEEIERPPSFFIGAVENPFAEPFEYRAPRLMKKIEAGADFFQTQIVYNVEK
FKKWMADVRKLGGHKKAYILAGVAPLKSAGMAKYMKKFVPGMDVPDELIKRMEKAKDAKE
EGINICVEIIKEMKKIDGISGVHIMAIEWEEAVPTIVERADLSPRPKVN
>X1EG84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MIRRISDILREKERTYSFELFPPKTEKGRERLPETAGTLKELEPDWFAVTYGAGGTTREL
TMDIVDELQKRLLVPAMHHFTCVGHSKAELEAIIKKMKEKNICNILALRGDAPEGVEHWE
PAPDGLEYCYQLIELIRSYDSFFSIGVAGFPEGHIDCPDKETDSRYLKIKIDTGGEFVIT
QLFFNNKDYFEYLERVRKIGVTVRIIPGIIPITNYQ
>A0A0F9WYM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MIQDLPLPRHHIPASIEVAPKQALESRELPDLFPAGTKVYLTDVGVDSVKDFIRAVKRIS
DLGYAPVPHIPARRIRSRDELETRIRAYAEEAGVTDMLVIGGGLDRPAGPFTSTMEILES
GLFDRYGIRDVGVAGHPEGSPDFSAATAEEALRLKRDFGERTGAHMRIVTQFGFDANEFI
NWSLAIREAGIGLPIHLGVAGPAKITTLIKYAALCGVGNSVAFLKKRALALTALATTHSP
EAVVGPIERHWQATLDSPVRQIHVFPFGGLVKSAEWLTERASWPNQASSFSRDIKRQHG
>A0A7S7U7A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. CCBAU 53340|TrEMBL
MSGAMTETTTPAAADGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYGA
GGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPA
GGIGTPYSSHPDGYQSSADLVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKAKVD
AGATRAITQVFFDNDFYFRYLDRVRARGIDIPVVPGIMPMHNFKQARNFVTRAGTTVPDW
FAAKFDGLDNDAETRKLVAAAVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRA
KSAQKAA
>A0A6P6V7M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coffea arabica|TrEMBL
MKVIEKIQKAAKDENKVVFSFEFFPPKTEDGVDNLFERMERMVVHNPNFCDITWGAGGST
XDLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALDAIKSNGXQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYXDYFGITVAGYPEAHPDVIPANGIASLEAYQSDLAYL
KRKVDAGADLIITQLFYDTDXFLKFVNDCRQIGITCPIVPGIMPINNYRGFLRMTGFCKT
KIPPEITAALEPIKDNEEAVRNYGIHLGTEMCKRILASGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRTLLGDVPLIFIVLEDVRPIFWYIILHQPIFALSLSLSLS
>A0A7Y2CYT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp|TrEMBL
MSVPTVSFEVFPPRTVDASFNLWDTAQALAPLAPRFFSVTYGAGGSTRDITHDAAHVLRR
TSGLPVAGHLTCVGASKAETLAVAESFAKIGVTDIVALRGDPEGGKERFEPHPDGFTNSC
ELIEALAETGRFNVRVGAYPDVHPEAADAKTNIDWLKRKFEAGACEAITQFFFEPESFLR
FRDACVKAGIDRPITPGILPILNWKSARSFAARCGTPVPDWVEQSFETAIRDGRHDLLAL
SLCTELCSTLIDEGVEQLHFYTLNRADLTRDVCRALGVTSQVALEDVA
>A0A0F9R076|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MAMTENKVYSKLGELIAKGEFVLTGELEPEKTCDLTHTIQEAKEMAPYVVAANVTDSPLA
IVTINSMAAAHIIQRETGLECVWQLTVRDCNKIGIAGQIMGAQALGLHNVLSLTGDHTAL
GDCPESKPVFDLDSATLIKLVREMVDTGSINGHEIEYPPKIHVGGAANPNSDPTEAEILK
IGRKAEAGVEFIQTQVVYDIDMTADFLREIRKYNVPVFLGIFPMKSYGIAKGFDMFVPGV
DVPKDILTRWKRVKTDVSDKKEQKETYDQLNYEFFKPFISELKSKGLLAGVHCMAVHYTR
IFPKLIDVIKG
>A0A6P6UZI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coffea arabica|TrEMBL
MKVIEKIQKAAKDENKVVFSFEFFPPKTEDGVDNLFERMERMVVHNPNFCDITWGAGGST
ADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALDAIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDVIPANGIASLEAYQSDLAYL
KRKVDAGADLIITQLFYDTDSFLKFVNDCRQIGITCPIVPGIMPINNYRGFLRMTGFCKT
KIPPEITAALEPIKDNEEAVRNYGIHLGTEMCKRILASGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRTLPWRRPTNIYRVKEDVRPIFWANRPKSYISRTIGWEHYPHGRWGDSRN
ASYGALSDYQFMRPRARGKRLSEEWVVPLRSLQDIYEKFKQFCLGQLRSCPWSELDGLQP
ETRIINEHLGAINLKGFLTINSQPAVNGVKSDTPSLGWGGPGGYVYQKAYLEFFCSKEKL
NSLVERCKAYPFLTYMAVDKAGSWISNTNQTDVNAVTWGVFPAKEIIQPTVVDPSSFVVW
KDEAFEIWSRAWAQLYPEADPSRKLLEEVRDTYFLVSLVDNDYISGDLFAVFNDL
>X1GIX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MANSLFEEKLNSDEFLVTTEVGPPKGADISELIKHIDLLKDKVDAINVTDHQSSVMRFPS
LGGCLLIKEHGGEPVLQITCRDRNRLAIQAELLLAYSRGIGNVLCLTGDSIDVGDHKEAK
PVFDLDSVQLLRLIRTMESGTDMGGNDLKGAPKFCIGASVHPEADFIEPQLIKFDKKVAA
>A0A0F9J544|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MTIRYELNPPKVDKDGLLSKDELAKKLDKFKNRVAEISSSCDGIHITDSVLGTKRISPLT
TAEMIRNNNSNLEVTVSLRVRDKKIEDIEKFVKDAIELELEGILIVKGDPSTEKPNNSGL
IPSQVVKHLKDSGFAEKIDLYLSLPSKPNFAKIQKKIDVKPKGFITQVIASTDQVTNIVD
ALKAHSFKIIPIVLFPSQKNLKSAEFLKLDWSNYQDNVLDFIKNVHNITGDVLITSPNDF
NGVRMTLRKLEI
>A0A8H5DW80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium anthophilum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLASDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A8H5DZ38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium anthophilum|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVRHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMTSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFGLLKGLEVKGLTTPATPLTESA
GNGAVGTEPIANGTAATAVAN
>X1IHW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKVVNLYKGNKPVFSLEVFPPRNGESLEAVLNTIDSLWSFKPAFVSVTGGALGSMRGGTI
AIAAGIKRKYGVEGIPHFTCVNKSKHDIENLLMEMKFNEIENVFALRGDPPMGQKGFIPH
PEGHKYASELVEQIKLLNEGVYILSSVEKDYKVSPT
>A0A6G9I8V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zophobihabitans entericus|TrEMBL
MSTFPHARQLHTLNQYVSDVQDKINVSFEFFPPKTEEMEHTLWQSIFRLATLKPKFVSVT
YGANSGTRDRTHDIIKAIKSKTGLVAAPHLTCIDASQEQLKQIAKDYWDNGIRHIVALRG
DIPAGQPNPQIYAADLVKLLKDVADFDISVAAYPEVHPEAKSAQADIDNLKRKVDAGANR
AITQFFFDIEQYLRFRDKCAAENINVDIIPGILPVSNLKQLEKFAQMTNVHVPNWLINMF
TNIDDDPETRKFVGASVAMDMVKVLFREGVRDFHFYTLNRAEMSFAMCHTLGVRP
>X1TW87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKMTEAKSYSKLGEALAKGEFILTGELEPEKTCDLSHTIEEARQMAPYVIAANVTDSPLG
IVTINSMAATHLIQKATGLECVWQMTVRDVNKLGIAGMIMGAQALGIHNILSLTGDHTAM
GDMPESKPVFDLDSATLIKLVREMV
>A0A5N6QZ48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carpinus fangiana|TrEMBL
MKVIEKIQAGLADEGKVLFSFEFFPPKTDDGVDNLFERMDRMVAHNPAFCDITWGAGGST
ADLTLDIANRMQNIICVESMMHLTCTNMPVDKIDHALSTIKSNGLQNVLALRGDPPHGQD
KFVQIQGGFACALDLVKHIRAQYGDYFGITVAGYPEAHPDVIGSNGVASLEAYHNDLAYL
KRKVEAGADLIVTQLFYDTDIFLKFVDDCRKIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPAEVSAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIRTLHLYTLNMEKSALAILMN
LGLIEETKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWADSCN
PSYGALTDYQFMRPRARDKKLLEEWATPLRSVEDIHEKFKKYCLGKLRSSPWSELDGLQP
ETRIINEQLGKINLKGFLTINSQPAVNGEKSNSPSVGWGGPVGYVYQKAYVEFFCSREKL
DALVEKCKAFPSLTYMSVNKEGSWISNAAKTDVNAVTWGVFPAKEIIQPTVVDPSSFHVW
KDEAFEIWSRVWACLYPEGDASRKLLEEVQSSYFLVSLVDNDYIHGDLFAVFADF
>A0A1G5N508|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afifella marina DSM 2698|TrEMBL
MTPAAHHADGPKRLELSFEFFPPKKPEQFAAFKDTAERLKAFAPDFVSVTYGAGGTSKDR
SFAAVEMLTQEVGLPTAAHLTCVSAACSETNEAIATFQTFGVRHFVALRGDPPEGPGTPY
APHPEGYTDTADLIRGLRRIDDFEISVSAYPERHPESPDWDTEIDILKRKVEAGATRALT
QFFYDNDDFERYVEKVAAAGITIPIVPGILPVHRFAAVHSFAGRCGARIPPHLLPLSELS
GEAHFEAAVDLAARQIDDLAQRGVSGFHIYTMNQHRLVSAVLKAARIFEGERTCCAA
>A0A1C2DNI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium hungaricum|TrEMBL
MTPPRPPQRDENPAGIHLPLEPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKVFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPVMQIACRDKNRIAIQGDVLG
GAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLSTPPQ
VFLGAAINPFAPPYDFRPIHLGKKIAAGAQFVQSQYCFDVPMFKTFMQKARDLGFTEKVF
IMVGVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEIPG
VSGVHVMAYRQEEYVAEIVDESGVLKGRQPWKREARADDARVAERLDHLLHDNVTETQID
MVKTAH
>A0A4S2ET99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriaceae bacterium|TrEMBL
MTADRTVAQIFRDFRQPVSFEIFPPKGELSAEEARSLAADLAPLDPAFVSVTYSAGGSGN
AGPTVEVASMIQRDHGIPTVAHLTCQGLTRAALAEKCAQMRAAGIRNVLALRGDPRPDVG
PGDFEHASDMIPFLVDEGFCVGAAAYPEGHISCLDPEVDVAYLRAKQDAGASFLLTQLCF
DNEACCRFRERCDKAGVTVPVSFGIMPFMSKSQVSRMVFMCAASMPAAVVKLLARYEDDP
EALRAAGVEYACDQLADLAAHGVDGLHVYTMNRPGVAAACAAAARGEGR
>A0A1V6JB66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin012|TrEMBL
MHVCEILSKTNKTLFSFEILPPLKGGSFNDIFNSIEPLLEFKPAYINVTYHQEEVVYKDR
GNGLVEKMVVRKRPGTVGIAAALQYTCNIQVVPHIICGGFTREETENALIDLSFLGINNV
LVVRGDPDRSQKTFIPEPDGHIHSLDLVKQIVDLNHGKYLEEDLQNSNPTNFCIGVAGYP
EKHPEAPNKASDLRYLKMKIDAGASYIVTQMFFDNRKYFDFVDNCHEIGINVPIIPGLKP
VAICQHLHLLPRTFGIDLPDDLAKELEKCKTSQEARNLGIEWTIHQTRELIAAHVPAVHF
YTMGRSDNIYRIASACF
>A0A2U0TS04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 103|TrEMBL
MKVTEHIEKAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKAGGNNFAVDLVSQINQLNCGKYLHDVMDADNKADFCIGVAGY
PEKHLESPSLLSDLKRLKEKVDAGADYVVTQMFFENAKYFEFVAKAREMGITVPIIPGIK
PIAVQKHLQILPQIFRIDLPEDLISAVDKCKNNAEIRQVGIEWAIQQSIELKAAGVPVLH
YYSMGKSENIRQIASQVF
>V9DL78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cladophialophora carrionii CBS 160.54|TrEMBL
MHISKKLAQAHQSNKPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
QLTCEMVNAAQSHYGLETCMHLTCTDMERTQVDDALRRAYKAGCTNILALRGDPPRDQEK
WEVKEGGFRYARDLVKYIRTKYGDHFDIGVAGYPEGCDDHRDVDVLIDHLKEKIDAGATF
VVTQMFYDVDIFLDWVKKCRDRGIHVPIIPGIMPIHTHAAFVRRANWTKCHVPEDWYKAL
EPVKNDDAAVRAVGKELVAEMCRKILDAGVLHLHFYTMNLAQATRMVLEDLSITPSTSGL
ALEKPLPWRKSLGLNRRDETVRPIFWRNRNASYITRTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANIKLWGKPKSLREVTSMFVRYLQGDLDRLPWSEGAISTEAESIKDDLL
SLNKRGFLTINSQPAIDGASSTHPVHGWGPAGGWVYQKAYLELLVFPSMFQKVIDRLDAN
KNLTYYAVNQKGELLTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WSKCYPAGSGSRKLIETIMGECYLVNIVNNDFHQTHEIFKVFDGLEVRDLDLVFEGTDAS
DHTNGTDSTREVLNGDAPVAEVEKSIANGEERKVPFPTNGVALKN
>A0A2N4UVN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium carnosum|TrEMBL
MVNQALATNTESELRVRYNDITRGVYFIGTTPPKTSTPLDEVEGIADRLVNRIKDLAIDG
LIVYDIQDEVSRTKKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSETEAFDEWL
NEAWHEYQVRDIVLVGSPSAKNEVSLPLSTAYQTLAEHQNNFFTGGIMIAERHAKKGNEH
ARLIEKYQQGCNFFISQAIYDTQATIDILTRYAIECKQDGIKPQRILLTFSPCGSAKTLE
FIEWLGVSVPEATSLRILNATNPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRK
EEIDGSILLYKLLRASMDSHLAKHEFRTLKNKVNVSV
>A0A3M7EQP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MANNPSHCCGTRNMDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRP
LFVNVTWGAGGSTSAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGVRN
ILALRGDPPRSDEYNDPNNPLSEQDDSNRDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGH
SDQSHPEHQSVEHDLPSLVEKTAAGADFIMTQLFFDVEAYNDYEKRLRSHESGLFKTIPI
IPGLMPVQSYQILRRTTKLSHASLPPDVLRRMEPIKADDEAVKRVGVDVLCEMVENMRRH
ESPCARGFHFYTLNLEKVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMV
EDAKRNRQRRKSSNRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPVNSRANTLAI
SEGQGSAGREATWDDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDIC
TIFRRHLQGEIEAMPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSNDPVYG
WGPKNGFVFQKPFVELFLPSADWQRLKPILQADDQVTYYAGNAAGDFQSSDENSVNPVTW
GTFAGKEIITPTIIEGDSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSII
HHGYLEKGALWDALIAA
>S2YJ82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HGB0020|TrEMBL
MGAAGLGALLESVRYEVLPARATEETVLAHVPRDVVLTVTASPVKGLEPTLDLTGRLTAH
GYRVVPHVPARLLRDDVHLKEVVERLRGAGVDDVFVPAGDADPPAGPYDGALPVLRRLTE
LGGPFARVGITGYPESHPLIHDDLTVQAMWDKQAHADHIVSNLCFDPRVLGEWIARIRRR
GITLPLYVGVAGPVQRAKLLAVATRIGVGESTRFLTRHASWFWRFAAPGGYSPDGLLARG
ERALTAPSAGVAGLHLFTFNQIAETERWRRTLLERLGTAAS
>A0A1G3QNF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium RBG_16_49_21|TrEMBL
MKTLSKLEKILESGKFAVTSECGPPRGVNPDVIRKKAELLRDAVDAINVTDNQTSVVRMS
SIASCIILKQMGLEPIMQMVTRDRNRIAIQSDILGAAAHGINNMLCLSGDHQRFGDHQKA
KNVYDLDSVQLIQTVRHMRDEGKFLSGEPLDGVPGMFIGAAENPFADPFEIRVPRVSKKI
SAGVEFIQTQCVYNLEKFEQWMDGIRARGLHKKVYILAGVTPFKSVGMARYMKTKVPGMD
VPDELIERLKSVAKEKQADEGIALCIETIERLKKIEGVSGIHIMAIEWEEKVREIAEKSG
LLPRPKV
>A0A2W6YIE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp|TrEMBL
MARNDHNEQAGAPLRISFEFFPPKSEEMEGQLWATVDDLSRWNPDFVSVTYGAGGTTRAP
TLSTVRRLISETTLPTASHLTCVGATKDEVRHVVDEFRAVGVRHFVALRGDPQGGMGTAY
QPHPGGFANAAELVAGLRDMGEFEISVSAYPEKHPESRDEAADIDMLKRKVDAGAHRALT
QFFFDNDIFERYLERVRAAGITIPIVPGIMPIQNLTQLKRFASMCGASVPSFLDERFVGL
DDQPQARAEVAAEVAAEQIEDLVRRGIGDFHLYTMNRAPLVNATLVNVGLKPSVKAVAGA
AA
>A0A285QRJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 1331.2|TrEMBL
MALGIASTRTDRALTVRDLLAAGKRSFSFEFMPPRSEVGEQKLWDAIRRLEPLDPNFVCM
TYGAGGSSRERTVNMVGRIATETTLTPVAHLTAVDHSIAELRNIIGQYADQGVRNVLAVR
GDPPGDPMGEWVTHPEGVTYAYELVELIKGIGDFCVGVAASPNMHPRSTDWDEDIRHFVA
KIRSGADYAITQMFFEVDDYLRLRDRVTAAGCEAPIIPEIMPVTNAKQLERFPQLSGAPF
PADLEARLRAAIDDPAALRAVGMEHATAMAERLLAEGAPGLHFITLNHSTATLEIYQNLG
LHQR
>A0A286A6K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter xixiisoli|TrEMBL
MKITEHIKNAKGKTLFSFELLPPVKGQSIDWIYKGIEPLLEFEPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADSSFVPTPGGHCYATDLIQHIKNHNAGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNTDFKYLKQKVDMGAGFIVTQMFFDNQKYFDFVNKCRENGINVPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNAEAKEIGTQAMIKQCKELIEFGAPVLHF
YTMGKPDQTKEIAKAVF
>B4EE72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610)|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAATATRTICERLAV
>A0A7G5DP63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MSPm1|TrEMBL
MSNLCSSSAGFSPYTLEVTGKGIQEVEQARAVIPAGTPINIAFLGNEDHAQRIQAAKVIR
ACGAEPVPIISSRRLRSEADRDELIGALVAQAAPKRFMFVGGDPATPAGPYQDSLALLAS
GVLERHGIDQVVITGYPEGHPKIDSGELMRALKWKLDFLREAGCRVEITTQFGFDAEAVV
RWIERLRQQGIDTPVRIGVPGPADVGKLLRFARQFGVATSASILRRYGLSMTNLMQRVGA
ERYWDQLQAGLGDRRLGSIGWHLYPFGGVEDGVTWINARLSVAASPQASSR
>A0A356DU31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MNISELFDHKKTLFSLEIFPPKKDTPYNIIYNTLLKLRGIPADFISVTYGAGGSRAQQDK
TIEIASLILRTYHTEPVAHLTCVNADREQVLETLRQLKENNVENIMVLRGDIAPDCPPKT
DFKYASDLAAFIKTHEPGFNLLGACYPERHYQAESMEKDIEHLKIKIDHGITHLITQLFF
DNEHFYAFRDKAEKAGVTVPIEAGIMPITNPRQIERTVALSGASVPAKLQRLFDRYSKNE
KALFDAGIQYAIEQSMDLIANDVRGIHLYTMNNVDIATRVSDAIQYIVAAENNPV
>A0A8J5QXW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] subhashii|TrEMBL
MKISKKLEQAHSGPHAPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPVFIDITWNAGG
RSSSLTNEMVYTAQSALGLETCMHLTCTNMKVELIDEALDKAFKSGCQNILALRGDPPLD
GSESTGDFKYAKDLIEYIRKKYGDHFNIGVAGYPEGHPEEQSATKTLEYLKDKCDAGADF
IITQMFYDVDNFIQWCSKVRKAGIEIPIIPGIMPISTYAAFVRRAKWSEIAIPPHFLEAL
DPIKDDDYLVRERGTELVSDMCTKLIESGFVNHLHFYTMNLERATVMILEKLNLIEAVKS
HDVAGASELPWRKSLNPERSKESIRPIFWQNRKYSYVTRTATWDEFPNGRWGDSRSPAFG
DIDLCASELLRQSPKRALELWGTPQNLKDLSNIIVSYLKGDLKALPWSDGPVGDDTKIIV
DDLVRLNERGFFTMNSQPALNAIKSSEKVFGWGPKNGYVYQKQYLEFFCHKDLIPKLLYK
IDQYNSSQGDASCSLISYYAVDKDGNLTTNCRDDDINAVTWGVFPGEEILQPTIVEKTSF
LAWKDEVYRLFMEWAKVIGSSLAGADSEKAATFAELMTTFSNEFVLCNIVNNDFIDENST
IFKLIEELEVSELA
>A0A7J8KD03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rousettus aegyptiacus|TrEMBL
MQQHLSRLIAPPWGLACCPLTPTVPILYGRNSAMVNEPRGHGSLNPRLEGSSSESSKDSS
RCSTPGLDPERHERLKEKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRFDQMGAGGPLF
IDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCRQSREEITGHLHKAKRLGL
KNIMALRGDPIGDQWEDVEGGFCHAVDLVKHIRSEFGDYFDICVAGYPTGHPDTGSFEAD
LKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVK
LSRLEVPQQMKDVIEPIKDNDAAIRNYGIEQAVSLCQKLLASGLVPGLHFYTLNREMATT
EVLKRLGMWTEDPRRLLPWTVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWG
NSSSPAFGELKDYYLFYLKSKSPREQLLKMWGEELASEESVFEVFACYLSGEPNQNGCKV
TCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNVNGLPSSDPVVGWGPSGGYVFQK
AYLEFFTSRETVEALLQVLKKYEQRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREII
QPTVVDPVSFMFWKDEAFALWIEQWGKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDN
CLWHVVEDTFELLSRPGSE
>A0A8H4X906|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sarcochroum|TrEMBL
MHIKDMLSDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTATDGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFVRWVKRVRERGVNIPILPGIMPIATYASFLRRANHMQAKVPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELEWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTVQEIAQLFVRYLQNEVESLPWSEAPLTTEADEIRDELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPSNGYVYQKSYLELLVHPDVFNKMITRIENHP
DLTFYAVTKDGELRSNVTSDSPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFGLLQGLEVKDLTTPATPLSKPV
ADNAVDTEPIANGTTATAVAN
>A0A340XPG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lipotes vexillifer|TrEMBL
MVNEPRGHGGPSPRWECSSSGSESSKDSSRCSTPVLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKRLGLKNILALRGDPIGDQWEEEDGGFSYAVDLVKH
IRSEFGDYFDVCVAGYPKGHPDAESFEAGLKHLKEKVAAGADFIITQLFFEADTFFRFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
ALSLCQELLASGSVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTGEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLQVNRRGILT
INSQPNINGKPSSDPVVGWGPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGDNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEA
ESPSRAIIQHIHDSYFLVNLVDNEFPLDSCLWQVVEDTFELLNRPPQSKRETEAL
>A0A1B8AGA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium poae|TrEMBL
MHIKDMLHDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WEAADGGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVRNDDVAVRNIGKTLVADMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPSAERP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNEANRKKWGEPKTIQDIAELFVSYLNGKTESLPWSESPLTTEADEIRDDLIE
LNKRGLLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPSVFDKMMSRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPV
ANGAVDTEPITNGANGTATTAVAN
>A0A1H9CF80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium NE2001|TrEMBL
MKIIDILDTRNMSLSFEVFPPKKESTFESVVEATEEIAATHPAFMSVTYGAGGGTSKYTM
EIAKNIREKYGVPTLAHLTCVSSSREMVQQKIKEMKEMGIVNVMALRGDLTPELEKTDPS
TWDYKHATELVRELKESGDFCVGAACYPEVHPDSVNQKDDLTHIKEKVDAGADFLTTQMV
FDNNLFFNFMYKIREIGVTVPIIPGIMPITNANQVARAIKLSGSFMPQRFKSLVDYFGND
PDAMKQAGIAYATDQIIDLYANGITNVHVYSMNKPDVAKAIMNNLSDILGKDFNR
>A0A1Y5PEY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Microbacterium sp|TrEMBL
MSSATPAAAVPFSFEIYPPRTDAGLPALHETIRRLAAAGPEFISVTFGAGGSTGGRSLEV
LTHILRETSIPPLAHLTCVGSSYADATTLIREFLDAGITRFLALRGDPPADAVEGEEYVG
DLSSAAELVQLIDRVQAERAPYTEAPVPGTPGAARVAPRTRVEIAVAAFPNGHPRSRHRL
EHIDALLAKQAAGATFAISQLFFHAHDYLGFADVARAAGVTIPILPGIMPITSPGRLRRV
VELTGEALPSDLAVALDVEPTVEGRREIGIQHAAALARDVLAGGAAGIHLYAFNNHDNVL
AVLREAGVRTRTEEFSA
>A0A1A8FFU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius korthausae|TrEMBL
MVNQVQRVDGSWLSCKSDSSGASNSGGESSKESSRCSTPVLDAVCSDRLRDKMRRRMESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEEEEGGFNYAV
DLVKHIRSEFDDYFDVCVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTF
LTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVVEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKREESVFEVFTCYITGQLNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDAVVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRV
NYHIVNVHGRNLTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWRVLDDMFELLDAPLETLADGMPG
DGSHDDGTLAE
>A0A1W6BCQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pelagibacter sp. RS39|TrEMBL
MKFSLEIGPQTDLDTVPQVKDVYVTMLPGGDYRETAQQAVELVKKGFNPVPHFPARSMQD
EKQLKDYVSRCKDGGVKQVLVIGGGREPMGKFDSSFQLLETGYFEKMTIGIAGHPEGSPD
ISDSDLEKAMIDKKPYADYIVTQWLLDPQPIIDFVSKQSVPVHVGITGPLKISSLIKFAN
IVGAKNSLNFLKSNFTKALDLLKPKDPNDLIGKVKSHTDFFHIYTFGGLKETNKWLKENG
YV
>A0A1H0LHV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus sp. DSM 45219|TrEMBL
MTRTVRELLAGGRPTWSFEFFPPKSPEGAAQLWTALRELERLQPSFVSVTYGAGGSTREG
TVSVTERIATETTMTPLAHLTAVDHSVAELRNVVSRLAAAGVRNLLALRGDPPGADPQAE
WVAHPEGLRYAGELVELIRSMGDFSVGVAAFPERHPRSPDFDTDVEMFVRKCRAGADFAI
TQMFFRAEDYLRMRDRVAGTGCDVPIIAGVMPVTNARQITRIVQLSGQAFPEQLAARFAE
LDGDGPEEKAAVRAYGVEVATELCRTLLAEGVPGIHFITMNRSTATREVYANLAAVGAPH
>A0A2E0ZF80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MTEYKSGSRLERVLRSGRFAVTAELNPPDSADPQEVYDAALVLSEVCDGINATDASGAHC
HMSSVAICALLTRAGYEPVFQVSCRDRNRIAIQGDLLGAAAMGVKNVLCLTGDDVSAGDQ
PQAKPVFDFDSIHLLRTAKIMRDKGMFLSGRKLTTPPQLFLGAASNPFVQPFDWRPLRLA
KKIEAGADFIQSQYCFDIPRFKKFMQRVRDLGLHEKVFFLVGVGPLRSEKTAEFMRSKVP
GVHIPDKIVERLRKTPKEKKREEGKKICVEIIQQVREIEGVSGVHVMAYRQEELVAEIIQ
ESGLLPRPMQTGFDKGQEKARMRKKKSDQ
>A0A0S1UUP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. FR-008|TrEMBL
MRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSVTYGAGGSTRSGTVRA
TRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVRHP
EGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVDKCRAGADYAITQMFF
DPEDYLRLRDRVTAAGCATPIIPEIMPVTSLRQIERFAQLSNAVFPRKLEERMRASADDP
AAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLGLHDDKG
>A0A6I4TD08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tsuneonella aeria|TrEMBL
MNAEIAHAQPLYASLPGDIGISFEFFPPKTEKMAETLWDSVRTLEPLRPDFVSVTYGAGG
STRERTHAAVQRIVRETAIPAAAHLTCVDASREEVDAVARAYWDSGVRHIVALRGDASDP
GGCYRPHPDGYANAAELIAGLLRIAPFEISVAAYPEKHPDSADERADLDNLKRKFDAGAT
RAITQFFFEPDCFFRFRDRAAAAGISREIVPGVMPVMSFASVQKMSGLCGTAIPAWMETL
FDGLDARPAARQLVAATVAAELCRRLYAGDVRKFHFYTLNRAELSYAICHLLGRRPVGDT
A
>A0A7W4JAN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconacetobacter tumulicola|TrEMBL
MSLPQPPGPGLSFEFFPPKTPKMAEALRQTASVLAPLGPRFISVTYGAGGSTRDRTLQTV
AELVRETNVPVAGHLTCVDATRAEVDAVARAYWDAGVRHIVALRGDPSEPGAPFVAHPDG
YAGAVELVAGLRRIAPFEISVAAYPETHPAAISPAADLDHLKAKIDAGATRALTQFFFEA
ETFLRFRDRATAAGITTEIVPGILPVANIAQAYRFAEMCGAHVPDWMRRLFDGLDDHPGA
RAMVTTAVTAELCRQLRDHGVTDLHVYTLNRPDAALALHRLLHSGGTS
>A0A411PG17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella maritima|TrEMBL
MAFHHAQHSHSLNQSLAELSDINVSFEFFPPSTPEMEELLWNSIRRLEPLNPKFVSVTYG
ANSGVRDRTHSVIERIQKETELVAAPHLTLVDASDEELVELAKHYWNSGIKDIVALRGDL
PDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDAKNAQADLINLKKKIDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFKQTKRFADMTNVAIPNWLHKQFEG
LEDDPATRKLVGANVAIDMVKVLAREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A7K9EKJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Baryphthengus martii|TrEMBL
MVNETQHTCSASSSSKSDAGSSSGSESSKDSSRCSTPVHDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVEGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAVGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGVPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A174IL67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospira pectinoschiza|TrEMBL
MEKLKIYLEAHKLITDGAFGTYYSRVYDTNELPESVNITMGRRVTDIHKEYINAGAKLIR
TNTFAANTVNLECNFDEVKANIKAAVANARQAVKECGREVYIAADIGPIPNDNLFDKQTV
VDEYVDIAKVFLEEGINVFVFETFADLSNISDAIDYIGSAATGGINIADSVLTDRPFVIT
QFAINQFGYSNCGLSSSKLVKLADDNPYIDALGFNCGIGPGHMEQFILKERRHTDKYLSA
LPNAGYPQAVSGRMIFSDKNMDYYSDKMCELLNAGADIIGGCCGTTPDYIDRIASKADFT
QNRQGEGCDWETDNSVQAVNTAFYHNKEGKKLIAVELAPPFDSNADKLLDAAHYLKSKGV
DVLTFPDSPSGRTRADSILMAEKVSRQTGMCVMPHLCCRDKNAIAIRSQILGADINGINN
FLVITGDPIPSVMRSSVKSVFNFDSVGFMNILDDMNSEQFADQPVTYGGAINQGRKRLDI
EIGRVKKKMEAGATFFMTQPAFCDEDIERIATIKKETGARILCGIMPLVSFKNASFMKNE
MTGINVTDEVLLRYRPDMTKEEGEQAGIDLAVEIINKSIDIVDGYYFSFPFIRVHMLDKI
IKQSELYVNN
>A0A2W1JM14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acaryochloris thomasi RCC1774|TrEMBL
MLKSAIKAGEFLVTAEVTPPKGGQVDHMVQQALTLKGWVHGINITDGSRAVLRMSSLASA
VILRQHGLEPICQMACRDRNRIALQADLMGAHALGIRNILALTGDPVKAGDYPKARSVFD
LESVRLLKTITQLNAGIDANDKPLPDGSTEIFAGAAVDPQLASWSGLQKRFERKVEAGAE
FFQSQLIVDFDRLDKFMSQIAEPHGKPVLAGIFLLKSAKNARFINRCVPGVNIPDWIIER
LERSKEPLQEGIAIASEQVQQARQICQGVHMMAVKREELIPQILDRAGVEPIACT
>A0A2G3PX00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIEHFFEQKKPIISFEIFPPKKESALRNLDETLEILSQLKPDFISVTFGAGGSCVNNQT
VEIAKKIKAKYHIEALAHLTCLNHNQDEINILLQELEKAGVENILALRGDKNPNVTPKKD
FTYASDLVAYIKSQGNFGLSGACYPEGHTECENEVQDILNLKKKVDAGVGHLISQLFFDN
DVFYNFQKNAQLAGIEVPIEAGIMPVINKAQIEKMVSLCGASLPSKFTKIMQKYEDNKEA
LFEAGIAYAIDQIVDLIAHDVEGIHLYTMNNPLVAQRIYEGIKKLL
>A0A3N1Y9U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Inmirania thermothiophila|TrEMBL
MQLSLEFFPPKTPEGEARWREALEGLAPLAPAYCSVTYGAGGSTRERTAETVFAIQARGL
EAAPHISCIGASRESIRELLRLYAERGIRRLVALRGDLPSGMRDIGEFRHASDLVAFIRA
ETGRRFHVEVACYPEFHPQAPDALTDLRNFRTKVEAGADGAITQYFYNADAYFRFVEDCR
RMRIGIPIVPGIMPITQFSQLARFSDACGAEIPRWLRRRMEAYGDDAASIRALGEEVVTR
LCERLLEGGAPGLHFYTMNRAEPTLAICRNLGLAPQAA
>A0A1G5WUX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium G11|TrEMBL
MISELLKQKETMSFEMYPPKKEDEFEKAFEVAKKLGDLKPDYISVTYGAGGSKSKKTVEI
TSFIQNELHIEALAHLTCVGNSKKDIDEIVESFKAEGINQVLALRGDRPRDMSDEQFNSR
ELIHASDLITYLKSTTDFSCAGACYPEKHFECFSKETDVANLKLKQDAGAEYFISQLFLD
NDYYYDFLDRAARKGITVPICAGIMPVISANQLGTTVSLSGSSIPKAFSDLIAKYGDNAD
DMRKAGIDYAARQIIDLRQNGVKHIHLYCMNRPKMTAEILEAIK
>A0A2I0AXP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apostasia shenzhenica|TrEMBL
MKVIEKVREAVDGEGRTVFSFEFFPPKTEEGVENLFERMDRMVSHNPTFCDITWGAGGST
ADLTLDIANRMQNMVCVIPPSISLLYSIEYYCCGENDLELCLLEVLDLVVLPAITIWSAD
YSFSEYISGDFKEISVETMMHLTCTNMPVEKIDHALDTIKTNGIQNVLALRGDPPHGQDK
FVQVEGGFSCALDLVKHIRAKYGNYFGITIAGYPEAHPDMIQGEGGATLEAYSNDLAYLK
RKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTR
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILAQGIKTLHLYTLNMEKSALAILMNL
GLIEESKVTRSLPWRRPANVFRAKEDVRPIFWANRPKSYISRTVGWDQYPRGRWGDTQNP
SYGALTDYQFMRPRSRGKKLQEEWATPLKSLEDIHERFMKYCLGKLTSSPWSELDGLHPE
TKIINERLGQINLKGFLTINSQPAVNGEKSDSATVGWGGPGGYVYQKAYLEFFCSIEKLN
KLVEKCKTLASLTYIAVNKEGHCISNVGPNAVNAVTWGVFPAKEIIQPTVVDPASFIVWK
DEAFEIWMRGWANLFPVGDPSRALLEQVQKSYYLVSLVDNDYIYGDLFAAFRDI
>A0A3D0DKJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKISEIYKNKKRSLSFEIFPPKKDSQLEDIDDTLDVLSELNPDFISVTFGAGGSSNCNRT
IELAKKIKYKYGIEPVVHLTCLHYDKTEIREFARVLKKEGIENVLALRGDKNDRVKEKDD
FKHSSDLIRFLKPDYDFCFLGACYPECHPESPDRVSELKCLRSKVDAGAEVLISQLFFDN
ETFFRFNEQCKIADINIPVIPGVMPVINATQIKRMISMCNATFPERFERIIKRYENNKEA
LFDAGMSYALSQIIDLLVSDIQGIHLYTMNNPAVARRICEGIKNIV
>A0A3B9WTQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIIDILKKPEFGLSFEVFPPKKETGYESVRLATEEIARLKPSFMSVTYGAGGGTSAYTL
NIGKNIKDKYGVPLLAHLTCISSDREKVRAQIEAMKEAGIENVMALRGDIPAEMSDSDRS
SWDYHYAIELVRQLKESGKDFCIGGACYPEVHPESVNQREDIRHLKEKVEAGVEFLTTQM
VFDNSLFFTFLYKLREAGVTVPVIPGIMPITNGNQVERAIKLSGAFMPQRFRAIVDRFGN
DPVAMKQAGIIYAADQIIDLYANGITNVHVYSMNKPDVAAGIQKSLADVMRSDVQTCEYT
>A0A368A5G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Tokpelaia sp. JSC161|TrEMBL
MSEGDENLSEKIHVSFEFFPPRTEQMEEKLWKTVHRLSPLNPHFVSVTYGAGGSTRERTF
RTVARLLKETDLVTAAHLTCVNATRAKVNKVACQFSQLGIRRFVALRGDPRKTSNSLDGY
ANAAELVAGLKAMNSDFDISVSAYPEKHPESPDFSTDIDQLKRKIDNGAMRAITQVFFDN
DVYESYLERVRAAGIQIPIVPGIFPIHNFLQVKNFCSRNGTHIPARLAHIFEGLEHEESK
THGLVSATVAAEQVFDLMARGIKDFHFYTLNDADLTYTICDMIGIRPQKKRK
>A0A372IEF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium W635|TrEMBL
MTGTSPDHPLPVSFELFPPKTEAGIARLRDTAERLAAVGPEYFSVTYGAGGSTRDRTARV
VDMVARHTHVPVAHHLTCVGASRADIDAQARDLWARGIRRIVALRGDLPEGETTPPDGYR
DAAELVAGLRRVADFDISVAAYPEVHPEAASPEADLDHLKRKLDAGAARAITQYAFDTDG
ILRFIDRARAAGIDAPIVPGIMPVANFASLKRFSANCGASIPGWFAATFEGLDDQPALRD
MVATSVATEQCRRLISGGAGALHIYTLNRAEVSLAICRALGVASELRAETAA
>A0A3D9H6B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella eximia|TrEMBL
MKVTEHIENANGKTQFSFEILPPLKGQHIQSIFNNIDPLMEFKPPFIDVTYHREEYVFKE
VENGLLKKQVVKKRPGTVGICAAIQNKYGVDAIPHILCGGFTKEDTENFLIDLDFLGIEN
VMALRGDAVKSETYFKPEKEGHSYANELISQIEEMNNGQYLDEELQNSSATNFCIGAAAY
PEKHMEAPSLDSDIHFLKKKIKNGATYIVTQMFFNNQKYFDFVAKCRKEGITVPIIPGLK
PISTKKQLNLIPHRFHVDLPEDLIISIVKCKDNKQVREVGIEWCIQQSKELQKAGIPVLH
YYSMGKSDNIKTIASELF
>A0A1Q9J587|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. 831b|TrEMBL
MRLTELLQKEEVTISCELFPPKLGTQLENYKNIVKQMAELKPAYMSVTYGATGGTSDYTV
ELANEVLNVNHIPALAHLTCASSTKEKVASVIEELKEKKIENILALRGDIPQNVDFPLPN
QYKHASELIADIKAQGDFCIGGACYPEGHPEADTIYDDLAHLKEKVDAGCEFLTTQMFFD
NNILYNFMYKALKMGIDVPVVAGIMPVTNANQVKRIMSLSGNMVPPRFLAIVDRFGADPD
AMKQAGIAYATEQIIDLIANGVNHVHIYTMNKPDIAGAILDNLSYIYKRDEK
>A0A3N4LAG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terfezia boudieri ATCC MYA-4762|TrEMBL
MARALRPLFVTITWGAGGSTAQKSLALAEVCQRHLGLTTCLHLTCTNMSRAVLDETLAQA
REIGVRNILALRGDPPRKDVYEEKDKEEVVDGVDGVNGAAGGNKEDLEFVYAIDLVRYIR
KHHGDYFCIGVAAYPEGHVDGSITTIPGDGTQDPARDLPYLVEKVKAGADFILTQLFYDV
DAYLSFERRLREHESGIFASIPIIPGLMPIQSYNTLRRIAKLSSAKVPKHVYDQLEPIKG
DDNAVKTIGVDILVDIVERIKSQSPVGEGVGDTTGLASRRGFHFYTLNLEKAVAFVLERS
DLIPPDDSIDRPDRESEEVATVVDGPNTAPSTTITINRAPHNGGRARRASSIDPYNSVIV
EDIRSELLQIHPANSATSAAITPTVSPTPNPPTIAISEGEGSLGRAATWDDFPNGRFGDS
RSPAFGEIDGYGPSLPLSTQQAITHWGYPTTTSDITSIFLRCIDGQVPAVPWSASAEGSG
GNAPGGGGLSAESNRIRHWLREMNVQGWWTVASQPAVEAGRSEDPEVGWGPKGGWVWQKA
FVEFWMPRGEWDGLRERLEREGAGEISWYVGDCNVCGLLPNHPETAVNAVTWGCFPGKEI
LTPTIIEHASFRAWLDEAFALWDQWAAIYPRRSATAKFLRELVWGRGGGGGVEAEGEGHL
CGGYVLVNVIHHGYADAEGLWRCL
>A0A415FI47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF46-10NS|TrEMBL
MKLSDAMREKMLLSFELFPPKTEKGMTNLPGTIEHLMKYKPEYISCTYGAGGGNVGANRE
VCQMIRNAGTIPVTHFTVIKNTKEGIKKQLQQYLAEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDEFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKLKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A2M7J241|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium CG_4_8_14_3_um_filter_54_18|TrEMBL
MNQSPISFEFFPPQTAEGVEKLTVVRARLATLKPEFFSVTFGAGGSTQERTVDTIRQIHA
EGYQAAPHLSCVGSTRDNIRAMLLAYRQMGIRRIVALRGDLPSGMAGIGEFQYANELVSF
IRAETGEHFHIEVAAYPEFHPQAQSAQADLLNFKRKVEAGADAAITQYFYNADAYFNFVE
AASKLGVTVPIVPGIMPIMRFSQLARFSDACGAEIPRWMRKTMEGYNDDTEAVQAFGLDV
ITALCEKLIAGGAPGLHFYTLNQAAPCLAIIE
>A0A523Z3M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Stahlbacteria bacterium|TrEMBL
MGNFRDVLNEERVIIADGAMGTMLYSSGVPKGRCFDELNLSDPEIVKGIHKAYHKAGAEL
LETNTFGANRLVLDRYFGLGDKTSEINYKGAKLAREVAEGAFVAGSVGPVTRPLDSSEKL
KVTDIEEIYSEQISSLLEGGVDLIILETMSDPEEARTGIRAARKLCDIPLLVSFSFSDEG
RTITGMDPIQVSRSLEKEGIKILGVNCCSGPRDVYMAIRRMTGKPDIWLSAMPNAGLPKF
IDRKFVYPHNPEYFAYYARKFLSLGVSIIGGCCGTTPLHIKAISESIVDEKVIKKKLKPL
QKKERTSLYRTEDVNTQLKKKADKEFIWIVEMEPPRGTDLNRELKLAKELQSIGVNALSI
SDSPMARVRMGPLALAHRIKDETSLEVILHKTTRDRNILGLQADCLAASALGIENMLALT
GDPPSAGDYPFSAAIWEATSKELIEMIKSLNSGRDLLGNQLQSPTRLWVGSASGIEPMKE
VFLRLKAKIEAGAGFIMTQPVFDLDNFSKFVKEVKKFDIPIFAGVMPLFSREQAEYLHNE
VPGIRIPEDIRKRADKDGVKIINEIISGLKELVNGVCIMLSKGKYSIIKELIQNK
>A0A841K6J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chelatococcus composti|TrEMBL
MSHAPFRPSRRGACPVRVSFEFFPPKTPEMEETLWASIKRLAPLGPHFVSVTYGAGGSTR
ERTHATVKRLVEETSLAPAAHLTCVSATREEVNEVVRAYWEAGVRHIVALRGDPAEGIGA
AFRPHPGGYEGSPELVAGIRAIADFDVSVSAYPEKHPESVSIDADIELLKRKVDAGASRA
ITQFFFDNDVYFRYLDKVRARGIDIPIVPGILPVQNFKQAANFAARAGASVPAWLANRFD
GLDNDVETRRLIAAAVAAEQVIDLVDRGVTDLHFYTMNRADLVYAICHLLGLRPTTAEAE
PVAAVAVA
>A0A842J7L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter massiliensis|TrEMBL
MLKEKILNKEKGLVLYGLTPPKAEFEESKLRDISDRWTGRIESINADGLVLYEVQDESER
NESERTFEFSGTLSPEIYYRDYLSVATPSVFYRVASGYDEEGFRAALAAQSSNLNVLVGA
TSSSQKVRFNLARAYEIAGEFENLAVGGVCIAERHAKKGDEPQRMREKIAAGAKFFISQA
IFDAQMTRKFLEDCAAAKITEPIFLTFSTAGNPKTLEFIKWLGVSVPSSVEDRLNASEEY
LAQSCEIIKEIWRELKKFGDENGLNLGANIESVMAKRAEIEASLELAREFRLL
>A0A0Q5UCZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. Leaf359|TrEMBL
MKVTEHIEKANGKSLFSFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYEYKE
LPSGLLEKKIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VVALRGDAVKNETYFKPEKEGNHYASELVTQITNLNKGIYLDDELQNSSSTNFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGASYIITQMFFDNKKFFDFVAKCRKEGITVPIIPGLK
PISTKKQLNLVPHRFKVDIPDELIMAIVRAKDADAVKQIGIEWCISQSKELIKEGIPVLH
YYSMGKSENIKAIAREVF
>A0A3N1RX32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 840.1|TrEMBL
MTTLREILVRPAASFSFEFFPAGTPAGMRALWQAIRQVERLAPDFVSVTYGAGGSSRERT
IEVTKRIVAETTMRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPNAPWI
PHPEGFRYAHELVSLVRELGDFSIGVAAFPERHPRSSDWESDIRHFIAKCRAGADYALTQ
MFFQVEDYLRLRDRVAAAGCDIPIIPEIMPATDARQISRFAELSGAAFPEDLAHRLNAAR
EDPALGYRIGVEYATAMAERLLAEGAPGLHYITLNRSTAALEIHRAVTGSRSVRRVEMLH
G
>A0A1W6VAK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio alginolyticus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEDTLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLIAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A4Y6QV35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. NIBRBAC000502771|TrEMBL
MAPAAASIPAAGQASGSGAALPVRMQVNPTEDVAALVQAHAPAGTALRVTCLPRQGVGPT
IRTAIELAYLGFEVVPHLAARSIESRGQLAGVVRNCHDAGITEVFAVGGDAGEPAGPYDS
SLPLLEDLAELSGGTIRAGVAGYPEGHPGHSELHMLDALLEKQHLASSVVTQLCFSASRI
QWYAETLRKEGVRLPVWAGVAGTVPRAQLIRAALKIGVGPSLKLLNRRGPLGRRLLKGGL
YSPQAILAELEGRGVVEGVHLYTFNNLAGAGS
>A0A1S7M6F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium fabacearum S56|TrEMBL
MLRSETARHNGEIRGDIRLSFEFFPPKNPEMENQLWETVAELKKWDPDFVSVTYGAGGST
KAPTLDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIG
TDYRPHPQGYENAAALVKGLRDISDFEVSVSAYPEKHPESASDAVDIDMLKRKADNGATR
ALTQFFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPSFLDERF
AGYDDDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSA
A
>A0A1G6H582|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostocaceae bacterium R-53105|TrEMBL
MSNHLKNNLYQNQLIFSMEVTVADLKRQDTVKKINQLTNLQYLSLVNHTKNDQEWQELLT
AGQALQMRTQRPLLLHLPAGTIAESQIQQKLIALQENQLDHLLIMRGDRVAPAANYHSAT
SLLKDINKSAFNFDLGATVDPNKIATLGLPALLSEIDTKIAAGAEFLITQIFFDLGLFKQ
LQEALQQRYPQIPLIAGVFPVMTVKQGQWIENNLGQGLPVTLTRRLMTLPADPQLKQYWC
GWLKELLLTGPAGVHFFAGIDIDFIKELMDIAY
>A0A2G4HCA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVVDHIQAAQGKTLFSFEVLPPLKGNTIDSLYSTIERLMEFGPKFIDVTSHREEFIFKK
HESGLLQKVHTRKRPGTVGICAAIQNKFHIDTVPHIICGGFSREETEYALIDLHYLGIDN
ALLLRGDALRSEGSFIPEPHGHSNAIDLISQVKNLNRGTYLYDEVENSNPSNFCIGVAGY
PEKHFEAPSFKADLKHLKAKVDAGGDFIVTQMFFNNEHFFKFVADCRAAGITVPIIPGLK
PLTTKGQLQGIPRNFHINLPDDLIEAVEAAKSPEAVKQVGVEWCIAQSKELMAKEVPVLH
YYTMSKAEETEQIAAAIF
>A0A128F432|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grimontia celer|TrEMBL
MLMTMNFEQGKVDCMPQLPDPAFAAAELIYHASLEATPRQVSALESRPEWLPEGIRVYVP
FLPSSNFEDAFDTCKALLIWGAVPVPHLPARAVPSEEKLREWLLALNVLGVKQLLLISGD
IETVQGPYADTMQLLQSGLLQEYGIESFGVAGHPEGHPHADQTALKHALEFKINYAKEHG
LSLWVVTQFSFDQTVLEQWLDEHQTILAGIPVYLGLAGPTRLKNLLSYAAQCGVATSAKA
LTKNINAVRLLRPWTPDSLLEGLAVYQSNRSESVLKGIHLFPFGGLKQSAEWLANKAR
>A0A2M6ZZ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG07_land_8_20_14_0_80_51_10|TrEMBL
MAKYMNENVPGIFVPQNLIDELAAAPKGEALKTGIAIAGRMIKQLKEENICDGVHIMAIG
REEVVPDILAAAGIVP
>A0A2H1JGH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei CIP 102111|TrEMBL
MSASALRSLLTSARYEILPTSGIIDRITDHVAPGRTITVTASTGLGLDATLSTAEQLQAL
GYDAVPHIAARMVQGRTELTEIIDRIGHAGIDTIFVPAGDATPPAGGYASALDLLVDLTS
MAPPISRIGVSAYPESHPLIPDDVTVQAMWDKRDYATHIVSNLCFDPGVVSTWLARVRAR
GIELPLILGIPGKVELAKLAKVAAKIGVGESTRFLRKNTGTFTRMARPGGYNPRKFLDRL
SPVLADPYMDVSGLHIYTFNQVKDTEAWRRKQLELLGDPDSSSFVS
>A0A6I6B6Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. MSR2|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEATLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNSGIRHIVALRGD
LPPGSGKPDMYASDLVELLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNAMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPHHN
>A0A8I0HXK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. CFBP 13617|TrEMBL
MTSLPLIDACPKRMEYGPCGGVGFHGSCEIDADHRCAFLHRPTVPWTGIDRSTVPAPAPR
TAGALATLDALGTRPWVVADLPARALSVASIDACAAVLAGEVDAVLAGDAGSARVQFPPA
YRASLVQRRGLRVWTGLNMRDRNRVAIEGELAALAVEGVAGVHCVTGDHTETGHRPDAAP
VFDLDSTEATALARAAGHVVSVAASPAAPPVERRAARLHEKLRAGADVCFVNHAGGAAPV
RRFIDEVSAEAMYIPCVPVVVDHASAALLESFTTLVLPEDFLSRVRDAHDPRAEGIALAV
ALAEEMLALPGVVGVNLSGGREGAEESFAEAMAEVSRRLR
>A0A1Q4YTQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix sp. CB00851|TrEMBL
MTSVVERLHGDSPAFSVEFFPARDEAEETVLWRAIRELEAFDPAFVSITYGAGGSTRDRT
IRTTSRVAQETTLLPMAHLTLVNHSVAELRNVIGWYAAVGVRNILAVRGDPPGDPNGEWT
AHPEGLIYAEELVRLCRELGDFCVGVAASPYGHPRSADLDTDTEYLVRKLRAGADFAIAQ
LFFQPEDFLRLRDRVAARGCDTVLIPGLMPLTTLRTLAKTVELSGSSVPDSVARRLDPYA
DDPAGFRAAGIDLVTEMGERLLAEGVPCLHFYTFNRSKATREIVGRLGLVPARA
>A0A1F4G673|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFCSPHIGHO2_01_FULL_63_240|TrEMBL
MTSLPISFEFFPPKTPEGVDKLAAVRQQLYALKPEYCSVTYGAGGSTQDGTIQAVRAILA
EGFDAAPHFSCIGASRASVREQLAQFKADGIKRIVALRGDLPSGYGAFGEFRYASELVAF
IREETGSHFHIEVGAYPEMHPQARNPQADLQAYVTKVKAGADVAITQYFFNSDAYFRFVE
DAEQAGATIPVVPGIMPITNASQLLRFSDACGAEVPRWIRTRLEGFGDDKASIQAFGLDV
VTDLCEQLRAGGVPGLHFYTMNQASTVKALCERLGLAGR
>A0A3C1WJQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacteres bacterium|TrEMBL
MSIAEKLKQGPTLSYEFFPPKNPAAWATLYGTLAETTKLGPDFVSVTYGAGGSTRSKTVD
IVGRIQGELGIEAMAHLTCVGHSREELRGILQSLWNAGIRHVLALRGDPPKGDTAFRPHP
DGFEHATELIRFIKENFSFTVGCAFYPEKHPEAKTLEADMAFLKLKQDNGADFAVSQLFF
DNGNFLRFRDEAAKIGITMPLLAGVMPVLEITQLPRFRDLSGCVIPDALVKFLGDGTDTQ
QKGVDYATRQCRELLDNGVSGLHLYCLNKHQSVVQITANLRDLGVLTRRVP
>A0A0D1ZDW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala mesophila|TrEMBL
MDDDRLPTLLSSLPPSSQYFSLEFFPPKTSSGFSNLQSRLARMTAALRPLFVTVTWGAGG
STATKSLELAEICQRQLGITTVLHLTCTNMKRAAIDEALESAKEVGIRNILALRGDPPRQ
EYRDTDENGSGGAGTDSNQEFAQAVDLVRHIRSQYGDYFSVGVAGYPEGHADESNPERGK
QSVDNDMPYLEDKVAAGADFIMTQLTYDVVAYQAYETRLRNHVTQDGRKLFANIPIIPGL
MPIQSYQIIKRITKLSHARIPDAIFQRIEQVKTDDEAVKKVGVQVLSEIVEQIKELPQPD
GMPRGFHFYTLNLEKSVAFILENTNLIPPISDSSPIDSSDSEALVDDDKVRNYTSARLPS
GQNGHVAHFSKRRASSMNAQPHNRVITDDLPHQNGHSRPTTDSRPLLSQHEAAGRGSGIP
ASIPTRKHNLLISEGQGALGREATWDDFPNGRWGPSHSPAFGEIDGYGPSLKVGPITARK
LWGHPKSSQDVTSLFRRVVTGDLEAVPWSDEVDVDGAGTGPGALRAETKVIQQDLLALIE
RKGYWTLASQPAVDGAKSEDETFGWGPPGEGFVFQKAFVEFFCSQEEWNQRLRPLLLKHG
EDKLGWMKTDAQGIFESSDEEFHRHSVDKPTSKRNPGVHGVSAVTWGVFRGKEIISPTII
ESESFKAWGEEAFSIWSEWRRCFPRGSDEEMLLDKLRTDSVLVNVVGQNYIKGHQGEGGE
LWRILLEEP
>A0A258ANQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium 12-59-8|TrEMBL
MHIQDILSATHGTTTFSFEFFPPRTPVAVKTLQSTLDLLAPLRPAFASVTYGAGGSTREL
TQSLVAELTQSDVFDPIPHLTCVGHSESEIMALLTRYAAAGVSNILALRGDLPAGHTDSG
VFTHAAELVRFIKQFNERGLHPHPRGFGIGVACFPEGHPATPNRMTEMDHLKAKVDAGAD
WLCTQSFFDNATFHDFRGRCALAGITAPILAGILPLTTATGMKRMAELAGGMRYPASLIR
ALNRAGDDPEAFRRIALHHATEQCADLLDHNVPGIHLYTLNQAQPVLAITSRLGLCRSTP
ATPAR
>A0A1S3JLQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lingula unguis|TrEMBL
MKDLQHSPDRSPQNGTPATPSPNSSRPESPGLLPYKYISLMDRIKAKIADDEPFFSLEFF
PPKTEEGAVNLVARLERMLLGGPLFCDITWHSAGDPTSDKHTSSTAIAGTMLNYVGMETM
LHLTCIGASKATMINQLERAKELGIRNILALRGDAKFGEEWKPEPDGFNYATDLVRFIRL
HYGDYFVICVAGYPSGHPDCESYEADLQNLKTKVDAGADFIITQLIFQSKTFLKYVQDCR
NIGITVPILPGIMPFQSYQSLRHITRLSKMEIPQEILDEVIPIKDNDEAIRNWGIDIAYR
MCSEILAAKGAPGLHFYTLNREVATVSVLKRLGMWCEEPKRMLPWKPTANHIRCMEDVRP
IFWRARQKSYVQRTSDWEDFPNGRWGDSSSAAFGALKDHYPFYLTSKSSHEELMSMWKKE
LNSEEDVWDVFYHYITGEAYDDGVKVTRLPWEDDEVTLETSLISSELASINRKGVLTINS
QPRINCVPSTDPAVGWGSHDGYIFQKS
>A0A837ITS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ligilactobacillus ruminis|TrEMBL
MPNQAVDSLITQMFFDNESFYRFRECCELADINTPIVAGIHLYTMNDAETAKYIWQATRS
LFENGRRVHQV
>A0A8H2WIR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKLTEKLANYASDVPYFTFEFFPPRTDQGYSNLLTRISGLASLKPIATSVTWGAGGSTRD
RSLDLAGFCQADNGLDTILHLTCTNMEKGTIDEALTTAMERGVSTVLALRGDPPRGEEYW
IPADPRFRHAEDLVTYIRQHPKFGGHFCIGIAGYPDGHSEGGTEQEQLTYLKRKVDAGAE
FIITQLFYDVDKFKSWLRKVRNAGITVPVIPGVMPLQTYATFTRMTDLCKATVPQHIQAN
LDAIKHDDQLVKEYGASLAVSMIRSILVDGDIKGVHFCTLNLEKSVRKILDELGWTHESL
HHNQIIIARGLFQDASQSPHILPAPADVPHPVAFTISPSEATQYATTSLAEHTRTGTVRT
AAEAIDSGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPPHVAIAQWGRPTTEQELSDLF
LAYLNDKTATTPFSPEPLSDESATILPHLVSFTKRGLWTVASQPAVDGALSSDPVIGWGP
RDGRVFQKSFVEFFATEADLEKVAKAIEDSGDGWVTFFAGNNEDGFLTNIPDSGSNAVTW
GVFPGKEIAQPTIIDRDSFLAWKDDAFMIWHDFGQCYPPDSPTRTLLEDVIKTRWLVSLV
HHDYKNPNALWDFLAKHLD
>A0A6P1JG46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. VKM Ac-2804|TrEMBL
MTNHSETAPESHCRAVPFSFEIYPARTATGARALERTVDRLAAVRPSFVSVTYGAGGSSR
SASLDILRYLREHTAAEPLAHLTCVGSTHAEANRLVHEFLEAGVTRFLALRGDPPTDAAE
DAPFLGELGSAAELVQLIHRVQAEREPYGAVTVLPNAQRVDVARRPRAQVAVAAFPNGHP
RSRSRSQDIDALLAKEAAGAAFAITQLFFHPADYLRFVERARAAGVTMPIIPGVMPVTSP
ERLRRMLELSGEDLPADLAIALDVEPDDDARIRIGVEHAAAMVRTLVDGGAPAVHLYAFN
RHEAVLEVLAESGLLPAAEPSTDAPTPARTP
>A0A8H2XSX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
CMHLTCTNMPQEKVDVALKEARANGCRNILALRGDPPSGQEEWTSVKGGFQHGIDLVRHI
RREHGDYFDVAVAGFPQTIQLPEAEAKQEMQWLKEKCDAGANFIFTQMFYDADVFIRWVK
AAREAGITIPIVPGINPIQTWNGFIRATSLSGTEIPQDLMDILEPHKNNDEKVRELGIKI
VADLCRKILNADIGIKGLHFYTMNLEKGTKMLLEELNFVPRVETIKPLPWRQSLTPTRRT
ETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELDGYGIWIKQTPEEGRKIWG
TPTTLDDIKSLFAKFCSQQIKALPWSDQPPSTEMLVIGQQLARMNELGYLTINSQPAVNG
ARSDDKAFGWGPKNGYVYQKAYLEFFVHPDQLQALIKRIERDTNVTYYAINKQGDLKTNS
TSEGPTAVTWGVFPGKEVVQPTIVEAVSFMAWKDEAFELGCQWAKIYEPGSPSRKLIEGI
MNEYFLVNFVHNDFHDREAIFRPFFVDSGLKANGDTETPAVNGIKVNGFVNGHATAVRA
>A0A1B9NQX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVQPKDDF
RYASELVTFIKENGDFNVIGACYPEGHLEAATLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYTFLDKSRDIGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPEAF
RDAGIAYAIDQIVDLVSQDVDGIHLYTMNNSYIARRISEAVSTLLAVPKSE
>A0A0G8G9K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ligilactobacillus ruminis|TrEMBL
MSQTTFSFEIFPPNKESAAEKLTETLDELVGLSPDFISVTCTNKNDDLARLTVKLAGYVK
NRLNVPSIAHLPAAYLDKQQVSEILNELETLGVTNLLALRGDRLKGRKPRDDFRHASDLI
AYVHENFPDFHISAACYPEIHPESNSRVDDIKHLKYKTDQGVDSLITQMFFDNESFYRFR
ECCELADINTPIVAGIMPIVKRKQALRILKTSSATLPKKFTAILNKYQDDPESLKAAGLA
YAIDQIVDLVTQGVAGIHLYTMNDAETAKYIWQATRSLFENGRKVHQV
>A0A0N1C6A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. AAP83|TrEMBL
MATPQIHPNWDKEPAGITDGFSLEMTAKDEASLRDAAPLIPAETPVAVTFLPGEDVAARV
AATVAVRELGFEPMPHFSARRITSEDDFEGYLRAVVEQAGVTRCFIVAGDPPEPVGPYFD
TSALIATGAFERSGIKAIGIGGHPEGHPNMTEAECWAVLDKKVAEITKRGMAPLIVTQFG
FDPDAFLAWLKTLRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVTN
LLGSAGPDKLVNAFAKGLGPEHGKVRLHFYPFGGLTKTLEWVQAYNAKQGL
>A0A562EN02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus rhodochrous J45|TrEMBL
MGELLGRQVIGAGRQDETSRSMGDGASEAGEPEVPRPAYPHSRVVAGSDRPGGATYAGPV
TSDFVRATEDGGISRTPSIVDRLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERLG
PAFVSMTYGAGGSTRDRTVRVTGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGIT
NILALRGDPPGNPLGEWEKHPEGLEYADELVRLVRDLGDFHVGVASFPEGHHRSPDLDHD
TRYLVQKLRAGAEYSITQMFFDVEHYLRLRDRVVACDAEQGLKPIIPEIMPITSLRSARR
SLELSGSHLPPVLEERLRRAAGDGPEENRAAVREVGIEVATEMCERLISEGAPCLHFITL
NFARATGEVLDRLGYELEAPAVVQPA
>A0A1V4RG53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium 4484_171|TrEMBL
MSFRDKIKSGKFVITMEVEPPKGNDTKGILSRIVPLKGKVDAYNVTDMQSSVMRMSPWAM
AIKLKENGFEPVMQLTCRDRNIIALQGDLLGISSFGIDNLLLLTGDSPARGDHPEAKAVF
DLDSIGLIEAAGSLNKGVDMAGNSLEGSPDFVIGAALNPFSKDIDREIEKMGKKIEAGAV
FFQTQPIFDVDRFHNFMEKVNVKNVTVMAGVIFIKSYRSAVYLNEKVEGIDIPPGYMKAL
KSADDFKKASFKMTKDIISSLRGICGGVHIMPLGLYDEVLGVLS
>A0A2D4VW53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MASTIEMISKAAADWSIEVTPTGATKIESFRDCLSPGTTVNVTFLPGTDPAETISVAERL
HNDGMRPVPHLAARSLRDADQLDELLAAFTSRCGVEEVLCIGGGVDKPVGAFDATIQVLE
TGLIQKHGIRSVGVAGHPEGSPDITDEEIAAALAAKNALAARDGLNLYIETQFCFEADIV
LDWERRVRAAGNTLPIRIGIPGPATIKTLFRFAQISGIGPSMRFVAKQAKNVAKLMTVQS
PHMLITGLAEGMAADDACLIRHFHYYPFGGFARTAAYAGGVAEGNIELLPKGGFDVIAN
>A0A520NHI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MAATIEQIRQAAEEWSIEVTPTGATKIESFRDCLAPGTTVNVTFLPGSDPIDTIAVAQRL
HDDGMKPVPHLAARSLRDKDQLDDLLSAFTSKAGVSEVLVIGGGVDNPVGQFSDTMQVLN
TGLIQKHGIRSIGVAGHPEGSPDISDDEIAEVMAAKNALAVREGLDLYIETQFCFEADIV
LDWERAARAAGNKLPIRIGIPGPATIKTLFRFAQISGIGPSMRFISKQARNVAKLMTVQS
PHMLLDGLAQGMAEDPDCLIRHFHFYPFGGFAKTAAYAQAIADGKIETLPKGGFEVIAA
>A0A521B2A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balnearium lithotrophicum|TrEMBL
MTFREKVESGKFVITAEVAPPRGTDFKPIVDGIEPLRGKVDAFNVTDCQRSMVRMGALPM
AKLLLDSKLEPIFQLTCRDRNRIALQSDLLGAYALGIENVCLMTGDFTTLGDQPDSKPVF
DVDSVQLIEIAERLNSGELLNGKKLNGKTSFFIGGVFNPFAGPKFLQELKLEKKIRAGAK
FIQTQPIYDSNLAKEVSELIYSLGATPIIGILPIKSLKMANFMKKLNPTSVPNSLIEGLE
RAENPEEYGWKYAIDIASSCLEFAGGIHFMLVGKVHELANFIDYLKRDYNHKF
>A0A2V5E8U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. RV120224-01b|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3B9D569|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp|TrEMBL
MKVSEILKKNEVTISCEIFPPKQGAQLQNYKAIAAEIAKLKPAYISCTYGATGGTSDYTV
EIADAINSYGVPAIAHLTCVSSTREKVHTVIHELKERGIENILALRGDIPTNTDFPLPDQ
YHHAIELIREIKEAGDFCIGGACYPEGHPEAANMNEDLDHLKEKVDAGCEYLTTQMFFDN
NIYYRFLYKALAKGIDVPVTAGIMPVTNAAQVKRTISLTGNLVPAKFLSIVDRFGDNPAA
MKQAGIAYATEQIIDLIANGVNHIHIYSMNKPDVAAAIMNNLSQIYVREQA
>A0A2D7TXN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MSLTIDKLSSAAANWSIEVTPTGASKVESFADVLEPQTCVNVTFLPGSDPADTLAVACRL
HEEGMIPIPHIAARSIKDKAHLQDIISALAKQAYVSEVLVIGGGVDKPVGEFDSSIQILK
SGILQSNGIFKIGVAGHPEGSPDISNDAVRHALHEKNELAVKENLQMYIETQFCFEADMV
LEWEKRVREDGNQLPIRIGIPGPATIKTLFRFAQISGIGPSMKFIAKQARNVAKLMTVQS
PHLLLSGLAEGMAADHQCLIKHFHYYPFGGFVKTAKYAKAISDGNVHLSPKGGFEILERQ
>A0A833DXQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrodictium sp|TrEMBL
MVKLVEVWVELEPTTRREKLEERLEKIKAYRVDALDIPDAPLGVPKAFAPLIACYIQATY
KIKAIPHLRLLDVNTNALLNVVGGLLLCGIDSFVILRGDRPKYGNPVEELNTDDALQVVR
GKYGDRVNIGCLVSLRKNVDEIIKRIEKDYDFFLLLRAFGENLEKIKVLRRVRTDAKLVA
YVIVCENENCRRLRDLLEGQPIVNVEHLHAHLDRLIEYVDGILLSSPGSLDTIVKTLELL
DKMGIL
>A0A7C1SQQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MVSAFQKALKSGKFVITCEAAPPKGTNLKRMAHDIELLKDKVDAINVTDHQSSVMRFPSL
GGALLVKEIGGEPILQMTCRDRNRLALQADLLFASYMGIHNVLCLTGDSIMLGDHKEAKA
VFDLDSSQLLGVVRKLEEGKDISGNDLDGGVSFCAGGIVTPEADPLEPQLIKFEKKIEAG
AEFIQTQAVFDLDRFKKFMEYAGQFKVKILVGIILLTSAPMARFMNKNIAGVFVPQDLID
EMASAPKGQAVAKGIEIAGRMIKRVHEEKMCDGVHIMAINKEELVPDIMSAAGLI
>A0A7W7AZI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingosinicella soli|TrEMBL
MILTLDQMTEAQNAVRQPLFADLKGDIAVSFEFFPPKTEKMEETLWESIKTLEPLAPRFV
SVTYGAGGSTRERTHATVSRLVRETTLTPAAHLTCVDASRGEIDDVARAYWDAGVRHIVA
LRGDPPRAGERFVPRADGYENAAALVAGLRRVADFEISVAAYPEMHPEAASIGQDLDNLK
RKLDGGARRAITQFFFEPETYFRFRDNAAAAGLDAEIVPGILPVSNFAQTKRMAEMCGTA
IPGWMERLFEGLEERPAARGLVAATVAAEFCRRLYAGGVREFHFYTLNRADLSYAICHML
GKRANGDRA
>A0A6I6G0P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia sp. DQ12-45-1b|TrEMBL
MDRIASSRTPRVPFSVEFYPPRDEAAEARLWRAASVFSELGAAFVSVTYGAGGSTRDRTV
KVVERVVRETDLVPIAHLTAVGHSIAELREMIQMYADVGVTNILALRGDPPGDPLGDWTP
HPEGLHYAEELVRLIHEVGDLHVGVASFPEGHYRARDLDHDTEILLNKLRAGAEYSITQM
FWDVEHYLRLRDRLESADPEQAVKPVIPGLMPVTSLRQVRRMVELSGCALPDGLSDRLRT
AAGDGPEENRAAVREVGIEFATELCERLIAEGVPCLHFNTLNFSRATHEVLANLSMVPSP
DVVASGV
>A0A7K9L147|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhabdornis inornatus|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPILDADRHERLREKMRRRQDAGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A1S0ZB97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Saintpaul|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3F3HV93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fructobacillus fructosus KCTC 3544|TrEMBL
MCGKMICELYQKRHGRVLSAELTKQKAEKLLQSGLTKREEGFAFFSLVNQGQTEDDFTSL
LALAGRLQRAIDRPIMVHLRTGDLSPQMLPEFFEQIAEAELVNFLIIGGDKRVHSGGFST
TEDLLKALRKGTPDRLSLGATIDPSQPAAPLKAKVRQAAGADFLISQVLFDEQPLLALQD
KLRKANPTFSIPLIPGLLLKPTLGQLRWVNHVLKVAIPDDYYAQPALAGQRLRTQLNQVN
FVGEHFFTVPEK
>A0A6J4IUK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Corynebacteriales bacterium|TrEMBL
AGRPGLRARRPAVPVRGARAGRGAVARRAGGAGAGAGAAAADRPHRPPVRPGLGPPGGPD
AGAGLRRPAGRRAPQPAGPAADAVRGRGAGRRRPAVDHADLPGPQPGRAGAGAGRAAVAG
RAGRALRDRRRPRPGRAAGRHPGLRPRRHPAGRAGRLARAAGRGAGGAGRADGAAAARPG
RGQAAGRRGAVRAQPRDHPGPGRGVRRGGPGGRGDAAVRGRGGGLHRRGVGPGAAALPRA
GDRPGGGRGGAGRAGRGRGRDRRRGGGGAGAAGGPRGGRGEPVRPGLRPGRGRGGGGQGG
GRRRGAGTGGSGM
>A0A660NQJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lautropia sp|TrEMBL
MTQHTASRTPQLSFEFFPAATDAGMQKLLDAHQALRTLDPAYFSVTFGAGGSTQARTTEI
VTALTQAGSQVAPHLTCVGATRESIRSLLDSYRDQGIRRLVALRGDLPSGMVGLGDFRHA
IDLIRFIRDAYGDWFSLEVAAYPEMHPQAESPDADLARFAEKAAAGAHSAITQYFYNPNA
YFDFVERAERAGVTIPIVPGIMPILNYTQLARFSDACGAEIPRWIRLRLASFHDDVDSLR
AFGHDVVVDLCQQLLDGGAPGIHFYTMNQAGPSTAIWQALGR
>A0A348SR92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia sp|TrEMBL
MSAQEHPLGISFEFFPPNTDAGREKLMRNRDLLAERNPRFFSVTYGAGGSTQNRTITTVN
AVRECGITTAPHLSCVGSEKAQLRELLTDYKAQGINSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAASFESDLQNFARKMNAGANLAITQYFFTADAYF
HFVERARQLGVEAPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSAAIADF
GEEVISRLAQRLLDGGAPGLHFYTLNQAEPTLKIVDNITGRS
>C5BC64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edwardsiella ictaluri (strain 93-146)|TrEMBL
MSFFHASQHDALNQSLAELQGQIQVSFEFFPPRSPEMEQTLWRSIDRLSILRPSFISVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCVDASREALRGIARDYWNSGIRHIVALRGD
LPAEGGRPEMYARDLVALLREEADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGASRA
ITQFFFDVESYLRFRDRCAAAGIDAEIVPGILPVSNFRQLQRFAALTNVRVPQWMLAMFD
GLDEDAETRKLVGANIAMDMVKLLTREGVKDFHFYTLNRAELSYAICHTLGVRPQGGVAS
>A0A1S9PIB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter pedocola|TrEMBL
MKITEHIANANGKTLFSFELIPPLKGESIQGIYNAIDPLMEFKPPFIDVTSLREDYIYKQ
HDSGLLEKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLQFLGIEN
VLVLRGDARRGDASFVPTPNGHCYATDLLQQVTNMNKGIYLHENHEGILKTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGAGFIVTQMFFDNQKYFDFVNACRANDIHVPIIPGLK
PLTTSKQLVNLSKTFHIDIPDDLSDAVHAAKSEKDVKEIGIEWTINQCKELVKFGAPVLH
FYTMSNPAGPTKRIAQAIF
>A0A3Z8SH41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHV
>A0A8G2MPD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae|TrEMBL
MMIAPQSESREKAPLADLLSHYSIEVTSRDLQSLESIAATLPQGSEVFVAHLPKEDIGLL
VRASAGLRDAGFVPVPHIVARHIRNRLELDTMLARLSEEAGVRHALVLGGDRDDAAGAFG
SSLELIETGLFQTYGIDRIALACYPEGHPRIAGAVLDTALTAKVDAAARAGLDVLLVSQF
LFDPKPLLNFARRLRERGVTAPLSVGIAGPASRTKLLKYALRCGVGASLRALRERSEIAR
NVFSGETPEELLMEIAAAQAAEPDLGISGVHFFTFGDPAQSIHWAEQQVDR
>A0A1R0LRD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. IMTB 2501|TrEMBL
MALGTPSTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPRGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDTDVSHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCGTPVIPEVLPVTSVKMLERLPKLSNAVF
PDVLKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A0M8W5B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia sp. NRRL S-836|TrEMBL
MTSVVERLQGQSAKFSVEFLPPRNADDERILWTAVRELEALDPAFVSITYGAGGSSRDRT
IRATARVAQETTLLPVAHLTAVDHSVAELRNVIGWYAAVGVRNVLALRGDPPGDPMGEWV
AHPQGLTYAEELVRLVRELGDFCVGVAAFPYGHPRSGDLATDVKFLVRKLNAGADYAVAQ
LFHEPEPFLRMRDSVAATGCTATLLPGIMPMLSARALTKIVELSGADLPVELSRRLERYS
DDPAGFRATGIDIATEMCQRLLDEGVPALHFYTMNRAKATREVLGRLGLVTRA
>A0A1G0FX16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_35_23|TrEMBL
MHSNQLTKNISFEFFPPQTTEHLDKLLETAQKLNSRSPAFFSVTYGAGGSTQERSLNTIQ
GLLTAKLTEVAPHISCIGSTKEKISELLAHYKSQGIRRLVALRGDLPSGLGTNTGHFRHA
QELVAFIRENSQDHFHIEVAAYPECHPEASSMQVDLKHFKEKVTAGADSAITQYFYNVEA
YEQFLNNCLKLNINIPIIPGIMPITNYTQLARFSDNCGAEIPRWIRKHLEDYGDNLDAIK
DFGIEVITKLCEKLVTLGAPGLHFYTLNKADSSLAVLANLNLI
>A0A0G3EKA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiritimatiella glycovorans|TrEMBL
MLIRDILDETSTAISFEFFPPKTERGWDNLFLNISSLVPLHPAYVSVTYGAGGSTRSHTH
ELVTRLQHDTDLTVLAHLTCVGSTRDEIAEILDNYAANGVQNILALRGDAPNDADEPVVT
PENGFDHASDLVSFIKERHPEMSVGVAGFVEGHPETPNRLREIEHLKEKVECGADFIITQ
LFFENRDFYDFSERCSLAGIDVPIIAGIMPITSHKNLEKMAELAAGSRVPAPLLRSLQWA
EGGEYVRNVGIHWATEQIRDLLHQGVAGIHLYTLNNSYASANICESLGLRSYERVTA
>A0A1C4AB30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga costaii|TrEMBL
MKITEHIANAAQSRQTLVSFEILPPLKGKSIESTYEHLDPLMEFKPPYVNVTYHRSEHMF
KKRPDGSFEKVEIRKRPGTVGICAALMNHYKIDAVPHLICGGFTREETENALIDLAYLGV
DNVLVLRGDAPKNESFFEAEPGGHRYAIDLLEQVANMNNGIYLEKDLQGGVKTKFCIGVA
GYPEKHAEAPNLQSDLAYLKKKVDAGAEYVVTQMFFDNQKYFDFVKRCREAGINIPIIPG
LKPLTSKKQLNLLPPIFNVDIPTELASEMMKAKSDKDAEQIGTEWLINQSKELKKFGVPV
LHYYTLGKSIVVRNVVAAIS
>A0A2D7GZR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHMHDILNRDKTIFGFEFFPPKTDDGWDGLVSRLHTFEALEPSFVSVTYGAGGSTRTKTH
DLVCHIAANTSLDPIPHLTCVGHSKQEITTILQSYQEAGIDNILALRGDKQQGGATPQDF
AHASELVKEVRAFAGKSFGIGVAGFPEGHPETPNRLVQMDHLKAKVECGVDWICSQLFFN
NNAFYDWVDRCDVAGIATPTLAGIMPITSIAGMRRMAELAGGANFPAKLQRRLYRFQDDA
DAVAKIGATWAAEQCADLLDNNVRGIHFFTMNKSTATEQIYSSLGALSGSKLRNSH
>A0A293NGT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHIHDXFKRDRQXFXFEFFPPRTDTAXDALLXRMDXFAALAPSFVSVTYGAGGSTXQRTX
DLVVQLNESDRVDAXPHLTXVQHTHDEIETILHRXADAGISNILALRGXRPLXXDXXPAX
DEYRHAADLVRHIKAFNESGAHRDPRGFGIGVAGFPEGHPETPNRLRQLEYLKAKVDEGA
DWITSQMFFDNVAFHDWCERCELEGIDVPLISGIMPITGIKTMQRMADLAGGTNFPAKLQ
RRIRRYQDDDDAIRQVGVQWATEQCNELLDHGVAGIHFYTLNRSGATLEIFRALGARDTG
SLRQ
>A0A139GGT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa (strain NIES-88 / KW-MA1-3)|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGVPPIHN
>A0A7D7KY44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria varians|TrEMBL
MSAPSLAPQPTQTRQQAAVADPPTGTSWLVRRPRRSTLVSFEVFPPRPDADPDTVWSRID
AMAQAGPDFFSVTNGHSAGTGVSREALRHLRRTTSTPVMAHFTCGGTDRAGLERSVEQLL
DDGVRDLLALRGDPPLGAGEWETPAGGLGRASELVSLIRDVERRRFGDGYRPGTRPLSVS
VACYPSPARGRDFEADLASLWEKQEAGADYAITQVLYEPEDYARFLERARSEGIHIPVVA
GLMPLTNPQRLRRMTEITGVAVPRRLTDFLAAGTPDELRRRGIAATLSLIDDLLDLGCAG
FHLYTFNRPDAALTILEHLRVRDAAREYRGRSPAA
>A0A182V3L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles merus|TrEMBL
MYDNRVLFHLLLSKRLILSDTLGRCHPAQLAKHLHSHTPVLPLPARRPEQPFRVPAFVSK
IINCASTLDSVMSVTSEPNNTMATTNTVTNEEKSNEDSLHTKLNRIFNSSTTTGPVPVHY
SIEIAAKDDFDIDQLKRLTPQPVFCALPWVSDDNLRYADDFLRSPTLQLTARLRENQYTV
LNNVSCYNITEQQVDQLLRSTGIRNLFVIRGDTVSPGQQFSNSAGLVQYLRKWQEQQPDH
RQLTIAVGGYPYGHYQSSSQTEELHYLQAKISQGADFLLTQTLYDAPSFLRYRDRCREAG
ISIPIIPGIYVPHSYRHLQALLNLTRIELGPTVRDAFEAHANDAPDQFQAFMVEYFVGVV
RELLQPNATTSSDPIKLVHFFTFNKFHLLQQVLEQLDEFFK
>W7TSL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nannochloropsis gaditana|TrEMBL
MKIIDKIKEAEEAAALNPHQKPPTFCSFEFFPPKTAAGVENLYMRIDRLASLEPLYIDIT
WGAGGSTADLSLQIAATAQRYLGQEVLMHLTCTNLDVEALKAILNAARQAGIQNILALRG
DPPKGASSWESCQGGLGYAIDLVRLIREEHGDHFCVAVGGHPEGHHHREGLADEGEGATG
VDLDKEIEHLKAKIDAGADFIVTQFFYDVEVYLDYVARCRAAGITCPIVPGVMPIQNYTL
FRRMTSFCRTRVPAEMWEQLAPIKEDEEAVRRWGVSFLTKLCRRLLDADVTPNLIHFYTL
NLEKSVRLILESLGLTATASIRRQFPWRSSKLSSRAGEDVRPINWANRPKSYLSRTEEWD
EFPNGRWGDGRSPAFGELSDYQFVDTSLGSREDRRAMWGEAPLKDVEVFEAFIKYVRAEI
PLLPWCEVPLQAETGTISADLVKINKAGFLTINSQPAVNGALSDDAVFGWGGAGGRVYQK
AYVECFTSQENLKLLMELCEKKPNLHYYAVDVAGNTYSNGSKKATALTWGVFPQCEILQP
TIFDPNTFLVWKNEAFQLWTSIWASIYDDESASNALIHKIHDTYFLVAIIDNDFSSTASM
WSVFREIIDEKEGTPLGGSQHHPQYSLP
>A0A2M9HSX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium scaligerum|TrEMBL
MHTPMFSLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHTDRTATARIAHTIR
NEYGIPAVAHLTALYSDKAKVDEALDMFEQAGVEAVLALRGDYIEGEETVGVFKHASDLV
AYIRERKPELKVFGACYPEGHYQAESLDQDIEYLKVKVDAGVTHLISQLFYDNDDFYRFI
DKARAAGIDVPIEAGIMPVRGAKSVRRMAERNASRIPEHLAVILDKWEGNSEALRTAGIA
YASQQIADLVAYGVDGIHLYSMNHPASTRRIWHNVQPLFGE
>A0A3C1LV93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKINEIARNKKVTFSYEIFPPKPNSPVLSVYESLDKL
>A0A2H6EAG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Abin03|TrEMBL
MKVIEHLKNAEEPLISFELIPPKRGGDIKSVLSVLDAIMKYNPPFIDITSHSAEVIYEET
PGGIKKKVKRKRPGTLGICALIQNKYNVDAIPHILVKGFTREETEDFLIELNYLGIENVL
AIRGDDSGYEKPLPLGKSTHRFTSELVKQITDMNKGKYLEDSLLDAKPTNFCVGVGGYPE
KHFEAPNLKSDIKFIKEKINAGADYVVTQMFFDNKFYFDFVDMCKQEGVNVPIIPGLKIL
TSKAQLHAIPKNFYITIPDALADEVYAAKPEDVLNIGVEWASKQVRDLLDKNIPGVHFYI
MLNSKPIRLLMDRLKLFKKKT
>A0A380RAT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKINKILADKTPTISFEVFPPKAETGLNDVKTAAGAIAALGPSFMSVTYGAAGSTSKLTV
EVASDIQNLHGVPVMPHLTCVASTKEHVANMIRQIRENNIDNVMALRGDLPKDGNVCHDF
EHASDLVREIRSLDPDICIGGACYPEGHIECAHKSDDIHFLKEKVDAGCDFLTTQMFFDN
NIFYNFLYRVKDVGINVPIVPGIMPITTAKQLSRSVQLSGTSVPERFKAIVDRFGDDPVA
MRQAGIIYASEQIIDLIANGITHIHVYSMNKPDVASDILYNLKGIIG
>A0A3D0WZ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
DNNIYYNFVYKLREAGISVPVVAGIMPVTNLRQIRRILALTGTALPQRFRYILDRFGDNP
AAMKQAGIAYATGQIVDLFANGVPAVHVYSMNNPSVAGKIRQNLSEILK
>A0A4R9Q041|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1D.F.Ca.ET.231.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAPRDQVDAVIREFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A4S9VLL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MTKLAVTRAIMHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRM
AHSLRPLFVNVTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAK
ALGIRNILALRGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVA
AYPEGHSDQSHPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGA
FKTIPIIPGLMPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMV
ETLKKNSYSGPKGFHFYTLNLEKAVAHIVERCKLIGAVNNVTVEDHDTPVANGNGDKKAK
ARRRSSIANSAPQNRVVIDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEG
ALGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFAR
HVRGELDAIPWSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPN
GFVFQKPFVEFFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTG
KEIVTPTMIEAVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFT
ENNGLWKMLLEA
>A0A4R6PX60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminicella lysinilytica|TrEMBL
MNLKLAELFGKGKTVFSFEVFPPKRDVPIETIYETLDELQYLKPDFISVTYGASGSLADN
STCEIASAIKADYGIESAAHLTCVNSTRHELDVMLERLQDGGVENIMALRGDYVPGIEPK
HDFEHASDLITYIKSKHYDFGISAACYPEGHPDSTDQVSDVLNLKKKVDAGAEHLVSQLF
FDNQIFYDFVDKAKIAGINTPIEAGIMPVTNSKQIERMVSLCGASLPAKFTKMMQRYENK
PEAMRDAGIAYATNQIVDLLSHNVDGIHLYTMNNPYIAKRISENVKSLL
>A0A3M1TD53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium J055|TrEMBL
MTPILSRFLNAVRAGEFLITAEVMPPKGGNPTHALEMAKGLKDRVHAVNITDGSRAVLRM
SPLVMSVLLLQNGIEPICQVACRDRNRIGLQADLMGAHALGIRNILALTGDPVKAGDYPD
ARSVFDWESVRLLGAISKLNEGLDANDKPLPDGPLELFPGAAVDPQLKSFSSLQRRFERK
IEAGAEFFQSQLISDFDRLDKFMTQVANGTGKPVLAGIFLIKSAKNARFLNKYVPGVHIP
EETIDRLEKATDPLQEGVAIAAEQVQLARQICQGVHMMAVKREDLIPQILDRAGIEPLT
>A0A4Q9J4R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Westiellopsis prolifica IICB1|TrEMBL
MLIFMLDTQNPSCLTSFQTAAKAGKFLITAEVAPPKGGNPEQMLKMAATLKGRVHAVNIT
DGSRAVLRMSPVIASAILIQHGIEPICQIACRDRNRIGLQADLMGAHAIGIRNILALTGD
PVKAGDHPDCKGVFDLESVRLLQVIEKLNHGFDCNDKPLTDGALDLFPGAAVDPQCPSWS
GLQKRFERKLAAGAQFFQSQLITDFEILEKFMDKIAADCGKPILAGIFLLKSAKNAQFIN
RCVPGVNIPEHIIDRLAKAKDPLEEGMKIAAEQVQTAQQLCQGVHMMAVKREDLIPQILE
MAGVAPVNQMVLR
>A0A1W1ZED3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKTTDLFGKKTVFSLEIFPPRADMGENVIYETLDALHDVNADFISVTYGRNSGQDGCRTV
KIASDIKHKYGVESIAHLPCSGVSKDTMIRILDALKENEIDNILALRGDLPDGEAVNGDF
LHADELISFIKSRYDFNILAACYPECHPEATSYDDDIEHLKRKVDCGADHLITQLFLDNT
HFYRFMYKAGRRGINIPVEAGIMPVTNKRQIERMVKMCGVELPGKFVKILDKYGDNEKAL
KDAGIAYAVDQITDLMANDVDGIHLYTMNDPYVAHKIYEAVCNLI
>A0A2N2MYW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-4|TrEMBL
MTDQVKLLERLKTGKPLLSDGAMGTMLHSRGITYEGCFDCLNLSHPGLVADLHREYIEAG
AQIIQTNTFGANRYKLGRHGLADSLGKINAAGVELARRAVLASFKEVLIAGDVGPLGVPL
APFGRVQADEARAAFEEQISALAAAGVDLIIIETMTDLHEIIEAVKASKSAAPQLPVIAS
MTFTRDNRTLLGDSPAKVAKGVHEAGADIIGINCSGGPNQLLNILKQMKSVLPEGLFSVM
PNAGWPEQVEGRIMYSAGPDYFGDYAVTFWQAGACVIGGCCGTTPAHIKAMADKITVTTA
VEVIAKRETEKSQVEKESEEVFPPTQMAQKLRDGKFVIAVEMDPPRGLSTGKLIAGASLL
SQAGADVIDVADSPMARMRMSPWAVCSLVQRKVGIETVLHFPTRGRNLLRVQGDLLAAHA
LEVRNIFVVMGDPTSIGDYPGANDNYDLVPSGLIKLIKQGFNAGLDHAGTEIGQPTNFFV
GCALNLNPVDMESELKNLRRKLKAGADFILTQPIYNPDLVTKFHEAYEREDGKLPIPLIA
GLLPLASARHAAFLQQEVPGIDIPAEVHQQMADSGNQGANTGIRLTVDLVEQIKEKVQGV
YLMPAFSRFDHAAEIIEQIRGNS
>A0A8C9TZ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scleropages formosus|TrEMBL
MVNQVQRMDGGSQAPKSDSSGASNSGGESSKESSRCSTPLLDADRADRLREKMKRRIESG
DRWFSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKDQITAHLAKAKRLGLKNIMALRGDPLADVWEEEECGFNYAT
DLVKHIRWEFGDYFDICVAGYPTGHPEAESYEADLKYLKEKVDAGADFVITQLFFRAETF
LKFVKDCRAVGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEAMMQVIEPIKDNDAAIRN
YGIQQAVDMCKVLLQSGDVPGLHFYTLNREVATMEVLKQLGLWNEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LVKMWGEELMSEESVFEVFTNYITTQPNRNGHKVMCLPWNDDPLAPETNLLKGELEKVNR
RGVLTINSQPNINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVQVKPLSFTAFVCEAP
>A0A8J7N3N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Odyssella sp|TrEMBL
MTRARASNGDAGLAEGPAPGGLAARVAALARGFSLEVSSRSARDLDACLTHVEKGTDVYI
NFIAGDDFGAKVRCAAALRASGFRPVPHVGARHVASAAQLDDLLARFAGEAGVDRALLIG
GDAAAPAGPFESSHSILASGLLAKHRFRAVGLAGYPEGHPQIAAPVLKRALADKLARAAE
QGLEPFIVTQFCFDAAAVSAWLADLRRDGVAAPVRIGLAGPANVATLVRFAIRCGVANSI
RALTGRADRFLRLVGDSAPDALVRGLAEDGAGIAGLHFFPFGGVAKTARWANALKRGRLR
ANDGGGLDVDV
>A0A7X9YH47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. KGMB02528|TrEMBL
MKVADIFSSAKATGAQPISFEMFPPKGELTLEHAREVAEQFQDLHPDFVSVTYSAGGSGN
SGATAKIASMLTHDFDITSVAHLTCISLTHDELQRKIDEMRQAGVENVLALRGDLPQGTN
AADAARAEYPYAKDLIPTLVDAGFCVGAAAYPEGHITCENLELSVEHLKQKQDAGASFFV
TQLFFDNECFFRFREMADRAGITVPITAGIMPFMSKQQISRMVFMCGASLPSPVIKLLAK
YEDNPDALREAGIEYACRQLEGLRDADADGLHIYTMNRPSVARAAIEALRK
>A0A0S6UDA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorella thermoacetica Y72|TrEMBL
MVESKMAKILSQGQFLVSGEIGPPKHADPTEIKKHAALLKDYVDAMNLTDNQTAIVRLSS
IAAGVHVLQAGGEPIIQMTVRDRNRIALQSDLLGAYSLGMRNVLCLSGDHQSFGNHPTAK
NVHDVDSLQLIRIVKDLRDEKKFACGEEIKGQEPRFFIGAAANPFADPFEFRVMRLEKKI
NAGADFIQTQCIFDMERFERFMALVRERGLHKRAKIIAGVMPLKSARAAKYMQQSVAGMI
VPDEIVNRMEKASDPKAEGVAICVEQIKHLQSIEGVAGVHIMAVMWEDIIPTIVKEAGLY
PRPKVE
>F2APP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula baltica WH47|TrEMBL
MQFAHQKNETLSFRSFFSFVICLMTLASVYQSTDCAISFELFPPKTSEGVDLLCKNVERL
MQFGPKYFTCTYGAGGSSQGTTLEVLQKVKQITNLPVASHLTCVGSTVKELEAYLTEAGR
IGVDYIVALRGDPPKGTTQFEVTEGGLKYANELVELIRGRFGDLGIAVAGYPETHQEAVD
FQTDLTNLKRKVDAGADIVITQLFYDNDDFYRFRDACEKVGIEVPIVPGILPVTNFKQAK
RIASMCKAAIPQSLESAMTEADDDQDQFRVGVEHARQQTIDLVNNGVPGIHYYVLNKSEA
AAELLDGLSLTSC
>F2TFS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces dermatitidis (strain ATCC 18188 / CBS 674.68)|TrEMBL
MEKISDKIAALPRNANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRSLVDHALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTYAVDLVKYIRRTHGDHFCIGVAAYPEGHSDESHPEVQDPARDVPYL
VEKTRAGADFIMTQLTYDLEAYKRFENMLRTHESGVFKDIPIITGLMPIQSYHILTRTTK
LSHARVPPNIMARVEEVKSDDESVKRIGVDILCEIVNGLKEIPCPGPRGLHFYTLNLEKA
VAFTVERCSLIPPSSEPSSDSEADLDTAVSMVHGQLNNIVRMSKRRASSINSQPHNRLIV
DRPSDGRGSSQASTTHETQTLGAGMPALNPPHRATTLQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVTPAVARRLWGYPTTKEDINTIFQRHVSGDLHIVPWSEGGT
QDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAF
VEFFCTAHDLKAILKPIFENHGHDELAWFATNAAGDFESSSPPTDDSANDYSGPVDVYLD
SNATAGGTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRVFPRGSPTEK
LLDQLKNDVWLVCVVGQKYGAGCQSREAAETEGKLLWKLLAGQATEADSTNKH
>A0A413RCN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM44-11|TrEMBL
MRVDEVFKQAASQGTTSVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A067D304|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprolegnia parasitica (strain CBS 223.65)|TrEMBL
MGKIIDRLLELEKTGTPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSGFK
DEKLWLKIGAHIQNEFKIDVLMHLTCHLPQDQLRVILQNARNAGIRNILALRGDPPIGAE
RWKAVPGGFRNAVELIRFIRQEHGDYFCIAAAGYSEVHTEAWNNPNLPPSDQVRNLDMLR
LKEKQDAGADFIITQFFFDVDKLSQWIRDCRTVGIRIPILPGYLPIQNFNSFLKFTNWCK
TSVPDHVVQALNLIKNDDAAVKKYGIQLAIDTCRKLMSQQLSLHFYTMNLASSVRSVLEG
LNLIPRRHERDLPWGLPMLRRKEGSADKVEQVRPIFWSNRASSYVARTSEWDDFPNGRWG
DRSSPAYGELSEYYLAYKRPKVARERVWGTPLTEQDVWSVFVKFIEGSVKTLPWCEQGLS
GESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKGGFVFQKAYVEFFVPPHL
MERLLVALKDYPNLSYHAFSANGTEYTNAPGPSVTAVTWGVFPGQEIIQPTVVDSASFAA
WKDEAFELWMSQWASAYASDSVSHAVIKEVYESYVLVNIVDHDYTNEDSDIFKIFARVIT
EGMTKDDLRGRVLELEDKNEKLHETVAKLKIIQAEASRELKEVHQELSASREENNRLKTQ
LRELRARAALSAI
>A0A379LYN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus gordoniae|TrEMBL
MDRLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERLGPAFVSMTYGAGGSTRDRTV
RVTGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWEK
HPEGLEYADELVRLVRDLGDFHVGVASFPEGHHRSPDLDHDTRYLVQKLRAGAEYSITQM
FFDVEHYLRLRDRVVAHDAEQGLKPIIPEIMPITSLRSARRSLELSGSQLPPVLEERLRR
AAGDGPEEDRAAVREVGIEVATEMCERLISEGAPCLHFITLNFARATGEVLTRLGYELEA
PAAVQPA
>A0A2N1XNT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium HGW-Gammaproteobacteria-5|TrEMBL
KVDAGADAAITQYFYNADAYFHFVDDARRLGIDIPILPGIMPIANFTQLRRFSEGCGAEI
PRWVVKHMAAFGDDREAVREFATDLVAGMCQRLLAGGAPTLHFYTLNLARPTLAVLDRLE
>D9S2E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosediminibacter oceani (strain ATCC BAA-1034 / DSM 16646 / JW/IW-1228P)|TrEMBL
MGLREKLESGGFALTAEMAPPKGVNTSRFRECARGVKGRVDAVNVTDFQSAVVRISSLGA
AIILLEEGIEPVMQLTGRDRNRIAIQGELLAAGALGIKNILALTGDHPVFGDNKQAKPVF
ELDSVNILQVATHLMEGKDLAGNPLDGAPDFYLGASVTPLFDPLELQVLKMEKKIEAGAK
FFQTQAVYDIEVLKRFREKTAHLDAKVLVGVIPLKSPGMANYMNKNVPGIFVPEVVIERL
RNSEDKVKEGLKIAAEFIMQAKEEKLCDGVHIMAIGAEENVPVLLDMCGF
>A0A1C5Y6Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Butyricicoccus sp|TrEMBL
MKISDILKQDKVTLSFEVFPPKNGSSYESVAQATQEIAALRPDFMSVTYGAGGGTSEHTV
HIASDLHKKYGVTVLTHLTCVSSTKAHVSSMLEAFKAHGLENVLALRGDIPAGGAPANDY
RFAAELVCDIKEQGDFCVGGACYPEGHVEASNKTEDILRLKEKVEAGCEFLTTQMFFDNN
ILYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITAMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAEIQASLSEILK
>A0A3R5Y7I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geovibrio thiophilus|TrEMBL
MKIIDIINSKRTISFEFFPPKKEEAESVLFDTISQLKKYSPDFVSVTYGAGGSTTEKTVE
WIRRTRVDYGLEVMMHLTCVAATCEVIKSVTSELDSIGVKNILALRGDVPLEMNTDEISK
EFEYASDLVNFLKKSGDYSVGVACYPEGHVQTKNIDKELEHLKLKQELGADFAITQLFFV
NDYFYRFIEKCEKAGITIPIIAGVMPITNISQVIRFTQMCGVEVPVSIISAMEGRSEEDM
FSLGVDYAVEQCADLWKNGVRGVHFYTLNRSGATEEVLKRLF
>A0A140D7N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella multocida|TrEMBL
MSYAKEIDTLNQHIADLNGKINVSFEFFPPKNEKMESILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLEAAPHLTGIDATPEELIEIAKDYWNSGIRRIVALRGDEP
KGYAKKPFYASALVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLVKMAAITNVKIPAWLAKNYEGL
DDDPTTRNLVAASVAMDMVRVLSREGVNDFHFYTLNRSELTYAICHTLGIRPSSE
>A0A1L5P5J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium etli 8C-3|TrEMBL
MALNTGDRRNIGISFEFFPPKSEEMEGQLWKTVAELQDWDPDFVSVTYGAGGTTKAPTLT
AVTRFLNETPLATASHLTCVGATKEETHQVIDHFRKAGVKHFVALRGDAPGGAGVPYEPH
PGGYANAAELVAGLREIGDFEISVSAYPEKHPESLDVAADIDMLKRKADNGADRALTQFF
FDNDNFERYLEKVRRSGVKIPIVPGIMPIQNLTQLKRFASACGTVIPAFLDERFAGLDDK
VEERAKVAVDVAVEQIEDLVRRGLNEFHLYTMNRSPLVSAVLTNLGLRREGAKRAAGAAA
>A0A4R1CWM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. BMG5.11|TrEMBL
MRESTASHERPARDFELICEIEPPTRPDLTHARHQIGVLSPVTDAFLIPDNHIGRATVSS
IAVAHEVQTMGGRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVHGDKPTAGNRTSDL
TVRAMIDEARAASEDPVFADMPAFRVGAAAGVRPLPTWKRAADFLFVQVSYSVDALLRWR
DAHPVELPVYAGVMVLASAGMARRLAATIPDIDIPDDLVHAVERDRTAGVETACDQVLQL
RDSGAFAGVHLVPVSRYRQVATRLEDLL
>A0A1W9J8U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. ST-bin5|TrEMBL
MSKEPRRLSEVLSSGQFAVTIEYNPPKGTNISKVLENAEELVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNSGRDMAGNKLDGSTAFTIGAAVTPEADPVGPMLAKFEVKV
KAGAQFFQTQAIYNPDLFASFMKAVRPYKVKVLAGILLLRNHKMAEFMNANIPGVSVPQE
MIDELKAAGNKAEDVGVEIAVRTINAVRAHCDGVHIMAIKGTHRLAEIITKAHLG
>A0A7X1AS95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cremoris|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTQYQQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEEDLRNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCESLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0C2FBR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylostoma duodenale|TrEMBL
LNDFVKVGHGNKYVPLHERINRRIKDKTPFFSLEFFPPKTANGVANFFTRLDRFNEGGPL
FVDITWHLGSDPANMNKETSSSSIAAGCLDYCRVDTMLHMTCAQYSKEQTIKHLEQSKSV
GLRNILALRGDLPNIDTDGIPIYKYRALDMIRWIREEFGDYFTIACSGEGIPSLLMFFTF
LQSRCFFLYIALHASNYFARVCA
>Q12UZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)|TrEMBL
MLSTFNDVLNSDRFIVTAEVAPPKGTDISATLEDAELIRGLVDAINITDNQRAVMRMSPI
AVGKLLMDAGHEVIVQLTCRDRNRLALQSDILAASALGIENLCVMTGDYTTKGDHVGAKA
VYDLDSVQLLSLITKMMGGSDMAGNELAGAPSFTVGAVSNTDVTKRMQMLKLKKKINAGA
RFIQTQAVYDVESFKDFSDLMGQIGPNVLVLAGIIPLRSAAMAHFMNNNIPGIRVGDELI
KRMENAKDPIQEGLEIAAESILELRDLCRGIHLMPIGGHGNTQRLLEMAGLDNR
>A0A0Q9YA64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Berkiella cookevillensis|TrEMBL
MSLPLSFEYFPPHSKQGLEKLIQTSQDLNKLHPEYYSVTFGAGGSTQERTLETCLALLET
TKTNISPHISCVGTEKESIRSLLNQYKIHQIKHLVVLRGDLPSGMVAMGDFAYANELVSW
IRKEYGDYFHIAIACYPEVHPQSFDAKKDFNYFKAKVEAGADEAITQYFYNPDSYFYFVE
HCQKENINIPIVPGIMPITNYNQLARFSSICGAEIPRWIRKHLESISDDPQSILSFGVDV
VTHLCDTLIQGGAPGLHFYTLNKSESTVEICNKLKLG
>A0A2E1RFC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovoraceae bacterium|TrEMBL
MKITDIISERKTPFFTFEIIPPMRGQSVKEVINTVEKLVPYNPGWIDVTSHPAGVVYKEN
PDGSIQKRIFRKRPGTLGICGIIKNRFNIEPCAHLLCNGFTKEETEDALIELNYLGVENV
LALQGDGLNYKKTPNPERSVNHYASDLVDQISAMKAGEYLDELTGARPLEFCVGVAGYPE
KHFMAPSLKQDMHYLKNKIDKGADFIGTQMFFDNSKFFDFKNACEEEGITAPIIPGLKIL
KSVRQLTTVPKAFHIDFPDELVEEIMSNQDHVEEIGLNWAIKQTKELIASGVSNVHFYVM
NDAEKVIKLMESL
>E7GFU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprobacillus cateniformis|TrEMBL
MKISDIYNKKKSLSFEIFPPKKDSELENIDETLKVLCELNPDYISVTFGAGGTSNCNRTI
ELAKKIKYEYHIEPVVHLTCLHYDKSEIDKFAKILIDEEIQNILALRGDKNPSIQEKGVF
KHASDLITYLKSKHDFCFLGACYPECHPESDNKINEMKHLKKKVIAGTEILLSQLFFDNE
QFFSFVEECRIADINIPIIPGIMPVINTSQIKRMVTLCGATFPERFQKIILKYENNKKAL
FDAGIAYALSQVIDLLANDIDGIHLYTMNNPLVASKICEGIRNII
>A0A387AYQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gwangjuense|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A0F3KED9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquitalea magnusonii|TrEMBL
MNEQKKTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGHAAAPHLSCIGSTRENISAILNEYRNHGIRHIVALRGDMPSGMVAAGEFRYANELV
EFIRSEHGEHFHIEVAAYPEFHPQAKSAEDDLNNFVRKVKAGANSAMTQYFFNADAYFRF
VDEAQARGVDIPIVPGIMPIANFGQLCRFSDMCGAEVPRWLRQRMQSYYDDAASIRALGL
DVVTELCDRLLANGAPGLHFYTLNQAGLVSTVWQRLGL
>A0A1F4Q2K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-1 bacterium RIFCSPHIGHO2_01_FULL_53_15|TrEMBL
MKVTEAFKKAAPALSFEFFPPKTPEQEEHLFDVIGKLKAFKPDFVSVTYGAMGTTREKTF
HWVETIKNKFKIEPVAHLTCVAASKKDIAGQLDQLDKIGIENILALRGDPPEGTTEFVPP
ADGFKFARDLIRLIKEKKPGFCLGAAAFPENTASLAYLKEKIEAGAEYAITQLFFDNRYY
FEYVEKARKAGLSIPIVPGLMTITNLKQIKRLTKVCGATIPEPLLKKLEALDGDTEAIHK
LGAEHTLAQARELIKAGAPGLHFFVMNQAEPIAQILKQLAR
>A0A344J2W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter oculi|TrEMBL
MAAVPLSFEFYPPKTDEQRAQLDRTVGKFKPHNPEYVSCTFGAGGSTLAYTSETVRHLRQ
RHEVEAVPHISCVGGSREELRELLKLYRALGCKKIVALRGDLPSGMGQMGELQYASDLIA
LVRAEHGNHFRIAVGAYPETHPQSRDAQEDLGNFKRKVEAGADVAITQYFYNSDAYFRFV
DDVRALGIDIPVVPGIMPISNFSQLRRFSDACGAEIPRWIEQRMRGFGDDADAVREFAAD
MVATLCRRLVEGGAPGLHFYTLNLAKPTLNVLTRID
>A0A024EEG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mandelii JR-1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>E1QIX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfarculus baarsii (strain ATCC 33931 / DSM 2075 / LMG 7858 / VKM B-1802 / 2st14)|TrEMBL
MAFAEALKSKAFVVLVEMETPKGVDISGFIDNARHVVGRVDAALIPDMSFAVMRMSALAG
AVLLKQQGLEPIIQFSCRDRNRLALQGDLLAAHVLGVANVMAIDGEAIEMGDHLHAKPVY
DLSAVGFLEAAQGLADGKDIGGRQLRGAPKFCLGARIEPWVDDAQCELRLGEARAAVKRG
AKFLVGPPVFDLESFAGFMAKAKDVGAPIIASVLLLKSVGMARYLNQNLPGVCISEDTIR
RIRQASDRPAECVKIAAETVKGLKKLCGGTLLVTAGWEDKLPGVLDAAGL
>C3DQ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar sotto str. T04001|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7J3VPJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrososphaerales archaeon|TrEMBL
MRMKITYEMNPPRIMTSNSHSNCNYPNTSQIERFDLQSLNSDLARFYSRVRALSGLAYMI
HVTDSVLGIPRLSSISIGREIVHKHKLRTRCSIRVRDRNTNAILQLVTDAILAGIDGLLV
IKGDEPKHSSIDSALKPSSVVRFMNEHGFSKHIRLYLSIDAENYSEDELNRKISAEPHGL
ITQSISSLEPLVLLADKVKANNMCIVPCIMVPSPKNRASAESINLDWSRYEHDLESFVLE
AYRLCGEVMITSPNSFNDGIDTLKRLMYGKAYKKGTMQRGSNTVGVEYKGEEGKNGMIR
>I4LR90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis 6420B|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VSYIRSKRPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNADCLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A845B4L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas coralli|TrEMBL
MNHFADHAASGTLQRWLTGPRVAGLPVPTELPPPALSFEFFPPRTETLEQQLWACVRRLE
PLAPRFVSVTYGAGGSTQERTHATVARLVRETSLTPAAHLTCVGASRGEVDDVARRYWEA
GVRHIVALRGDAPAGEAGYVPHPDGYAYAADLVAGLRRIGDFEISVAAYPETHPTASSPD
TDLDNLKRKIDAGATRAITQYFFDTEVFLRFLDRAHAAGITVPIVPGILPVSNFTQVRKF
SGMCGTTVPGWMGRLFEGLDDDPETRRMVAAALAAEQVRLLQANGVDEFHFYTLNRADLT
YAIAHILGVRPQPGALP
>A0A7D8UDP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MSLSEHYHHRRRGLSFELFPPKTPAAMGALEETIERLVRFEPDFFTCTYGAGGSSQRATL
DVVRMVRRIANLPVASHLTCVGSTVEELRAYLEEALAAGAEYLVALRGDPPKGTTEFRQV
AGGLRYANELVELIRREFDDRFGIAVAGYPEVHQEADSAEADLVNLKRKVDAGADVVITQ
LFYDNDDFYRFRDACEAIGITVPIVPGLLPVTNFKQIERIAKLCKASIPTAFAERMNEQD
SADWQFRVGVEYARAQTVDLIAHGVPGLHYYVLNQSNAAEVLLDGLELADAIA
>A0A1E5BDH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio genomosp. F10 str. ZF-129|TrEMBL
MGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLIAAPHLTCIDASRDELIQIADDYWNNGIQSIVALRGD
IPPGGGAPDMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQG
>A0A1D7U7I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea vaviloviae|TrEMBL
MMNAFRPSRHGSRRPKVSFEFFPPKTAEMETALWESVRRLEPLVPSFVSVTYGAGGSTRE
RTHATVKRMVEETALKPAAHLTCVSATCDEVDDVIRSYWEAGVRHIVALRGDPAGGLGTV
YEPHPQGYHQTSDLVAGIRRVGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAI
TQFFFDNDVYFRYLDKVRARGIDIPILPGIVPVQNFKQTANFARKTGASVPQWLADRFEG
LEEDAATRRLVAAAVCAEQVLDLIDRGVSDLHFYTMNKADLVYAICHLVGLKPEKTAAQA
VAAE
>A0A3C1X6G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MRLTELFNSRRFVLSIEMFPPKTAESGEALKRSLLSLNRFRPAFVSCTYGAGGSTRGQTL
DWCQWIQQTLQCPAMAHFTCVSSTVTELSAWLDEAWQAGVRNIMSLRGDPPAGQQVFTAA
EGGLSHASELTALIRRQYPDMGIGVAGYPEKHVEAVSMDSDLQHLKTKVDAGADAIFTQL
FFINDSFLKFRDQCSTLGINVPIVPGIMPITDFARIRRITAMCGSVIPAELANRLEAVKE
DSAAQFEIGVEYAIRQCQQLQAAGVPGIHFYALNKSDACERILQALNLPVA
>A0A0S4LHI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrospira nitrosa|TrEMBL
MSREPQRLIDVLNRGTFAVTVEYNPPKGTNISAVLENAKQLVGRVHGVNITDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGKDMMGNKLDGSTAFTIGAAVTPEADLVGPVLAKFEVKV
KAGAQFFQTQAVYNPDVFASFMKQVQPFKVKVLAGILVLRNHKMAEFMNANIPGMSVPQE
MIDELKAAGDRSEDVGVDIAVRSIKAVRPHCDGVHLMAIKATHRLAEIITKAELG
>A0A0C2X4Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amanita muscaria (strain Koide BX008)|TrEMBL
MKITQKIQQCAKEDRIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSEMVKTCQSLIGIETCMHLTCTNMPEEKVDIALREAKQHGCRNILALRGDPPMGKND
WQPVDGGFVHGIDLVKHIRSLYGDYFDIAVAGFPQQALLPPEELAQELRWLKEKIEAGCN
FIFTQMFYDVDVFIKWVKAVRDAGITIPIVPGIAPIQTWNGFLRATSLAQTIIPQSFLDA
LEPYKNDDEKVREIGTRLVADMCRQILQADLGIAGLHFYTMNLEKGTKMLLEELDLVPRV
ETLKPLPWRQSLTPNRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGVWLKQTKEDALKLWGYPTTFEEVTNLFARFCTGELKALPWSDQPPAGETSVISKQLA
QMNRLGFLTINSQPAVNGAKSDDKVFGWGPSDGYVYQKAYLEFFVNPALLSILLEQLEKD
PNVTYYVINKRGDLRTNTRSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAYELGQQ
WALFYEPDSPSRKLISDVMETCYLVNVVHNDFHDADAIFKLFWKAGAQYEATQANRSAIN
GINGH
>A0A0M1UZG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paeniclostridium sordellii|TrEMBL
MSLLKEALESGKFAVTAEMAPPKGTDLSHLIKCARAVKGRVHAVNVTDFQSAVMRTTSLT
TCKLLKDEGLEPVLQVTGRDRNRIAIQGELLSAGVFGIKNMLALTGDHTIVGDHPQAKPV
FDLDCVGILKTAQKLSQGTDMVGNQLKGAPEFYLGASVTPRYTPIEVQLLKMKKKINAGA
EFFQTQAVYDIDTMRDFRSHTKDMNTKVLAGIIPLKSPGMAKFMNVNVPGIYVPEELIDR
LKSVGKENWVNEGIKIAGELIKQLKEENLCDGIHIMAIGAEENIPAILDAANI
>A0A2G8EA75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia sp. OLSSP12|TrEMBL
MSFFHANQREALNQSLAELGGQFNVSFEFFPPRTKEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKVIKERTGLEAAPHLTCIDACRDELKTIAQDYWKNGIRHIVALRGD
LPAGSGKPDMYACDLVALLREVGDFDISVAAYPEVHPEARSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFRQLQRFATLTNVRVPGWMTSMFD
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVVNAA
>A0A4S8QIU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrytis galanthina|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHHIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAAL
EEVKNDDAAVRNIGKDLVAEMCRRILEAGVHHLHFYTMNLAQATRMVLDELRLTPSNQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLENSIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAVDGVKSSDPVYGWGPANGYVYQKAYLELLVAPDMMPELVRRIQHEP
DLTYYAVKKTGDVQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWYLVNIVHNDFHKSHGLFPLFDGLTVKNLNESFETSENGD
VDGVRFIEPQTVPLTNGEANGH
>A0A383TAY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus shcherbakoviae|TrEMBL
MKIESKFQKKKPVLSFEIFPPKRDKAIQNIDETLAILSELNPDFISVTFGAGGSHTNNQT
VELAKRIKHQYGIDPLVHLTCLNHSKFEICELLEELRAADIDSILALRGDTNPAVEAKKD
FRYASDLVKFIRQYGDFSISGACYPECHTESKNKVEDIAHLKEKVDSGVQHLISQLFFDN
NAFYSFQEHIQIAGMHVPVEAGIMPVINKAQIERMVTLCGASLPEKFSRVMHKYEDNKEA
LFDAGMAYAINQIVDLLAHDVDGIHIYTMNNPIVAKRICDGIKNLI
>A0A0C2X6H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amanita muscaria (strain Koide BX008)|TrEMBL
MKLIDKIATSTKPFYTFEFFPPRTEQGFENLLIRISRLATLNPLAVSATWGAGGSTKERS
LELAGLTQINCGLDTILHLTCTNMEQGMVDEALKAAKDRGIQNILALRGDPPRGAEEWLP
IDARFRNAADLVRYIRSVPEYATYFCVGVAAHPDIHPESTSDGDVEIEFLKAKVDAGADF
IITQLFYDVDSFYVWFNKVREKGINVPIIPGIMPIQTFSSFKRITKLCGTKVPASVSGEL
GSISHDDQLVKEYGISSAVDMIKKLTENGSIHGVHFFTLNLEKSVQCILEKIRWTGSVEP
IHNKLIADLPDGSHSYRAPEFLVTPTTAADTATKGLASIPATEGEIGRGELNNASTWDEF
PNGRFGDYKSPAFGDQGLWGNPAISKDDPVIQWGSLKTLNDLTNFFLDHLQGRIATTPFS
PGPLSLESQPILLNLEQLTRKSWWTVGSQPAIDSASSSDPIVGWGPRGGYVFQKSFVEFF
CDEEDVNEIKKQAQLKGEQVHWLASNNQGEFRTNVADDSRNAVTWGIFPGQEVVQTTIIE
PESFLSWKEEAFSIWSDWASFYPPQSEARSLLEQVRDQRWLISIVHHDYKNSGALWNFLH
EVNNAV
>A0A7V5AME2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium|TrEMBL
GFVDGINVTDNQTSVVRMSSLSACVILKNMGLEPILQMVCRDRNRIALQNDILGAAALGI
NNILCLSGDHQKFGDHPQGKNVYDIDSIQLIQTVKRMRDEGKFIGGEEIKGKPMLFIGAA
ENPFADPFEIRAARLAKKVAAGCEFIQTQCIYNIDRFARWMEMVRERGLHERCAILAGVT
PFKSVGMARYMKNNVPGMDVPDEMIERMKNTPKEKQAEEGIKICVETIEKLKEIPGVRGI
HLMAIEWEEKVPEIVKQANLWPRPEV
>A0A2V7DTF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFDRRLADGPLLCDGAMGTLLYARGVSLDACFDVLNVNHPKVVQSVHAEYIAAGSDC
IETNTFGANRFKLAVHGLADDVREINLRGVKLARDVRESMGRDVLVLGSIGPLGKYLAPL
GTVTADEARAAFREQAEALLEGGIDAFVVETFSDLTEIALAIEAIRALTDLPIVAQMAFT
DEAVTFAGRVPAEVARTLRELGVRALGANCSVGSSTLYEVLEAMVPEAREVPLAIQPNAG
LPHRIGERLMYLSSPGYMADYAGRMIDAGARIIGGCCGTTPQHIAAMRRVLDARAPASTA
EARPAGVRSVVETLEAPGLRTTLAPTLLGRKLEQQDFIVTVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLPTALLVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALGIRNILAMTGDPPRTGDYVNATAVFDVDGVGLIEVLRRMNEGMDATGNGIGEPTSFCV
GAALDPGAPDPGREAERFHRKLEAGARWFQTQPVYELDVLDRFLARVGGSPVPVLVGVLP
LHSFRHAEFLHNEVPGITIPDGVRARLRAAGDGALRAGIEMAQELIGEIRARYAGAYLMP
SFGRFEVVAEVLDVLR
>A0A2V6T3Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MSAPFIERLRERPLLGDGAMGTMLYARGVPLDACFDVLNVNEPKIVQGIHAEYIQAGADW
VETNTFGANRFKLGVHGLAAQVREINLRGVKLARDVRETLGRDIFVLGSIGPLGKYLAPL
GSITPEEARAAFREQAEGLLEGGVDAFVVETFSDLQELRLAVEAVRAITDLPVIASVAFT
QDHVTFLGSTPAEVTRTLRELPIQGLGANCSVGSSTLYEVLEQMLPEAGGLPVSIQPNAG
LPSRIGERLIYVSSPAYMAEYAARMIGAGARLVGGCCGTTADHIRAMREAVDRHVPSRDG
RTAAPRRARVEREAAALITTAAPTLLQRRLEAGEFLVTVELDPPRGHNIEKLVQGAKLLK
ERGVEIVDINDGSLGRVRMSVLPTAILVREATGLDINMHFTCRDRNLMGIQADVLGAHAL
DIRNILAMTGDPPRGGDYVNATAVFDVDAIGLIRILTEMNEGRDATGNSVGEPTAFCVGA
ALDPAAADPSREMERFLAKAEAGARWCQTQPIYDLEVLERFFARTRIPPQRGARDHHSRR
RPGTHARGGRAWSASRHRDGARARPPPSGPLRRRLSHAFLRALRSRRGSSGRAPVVTSAA
AGEPMADLNDVSAAEAARRIRSGALSPSNLLAACLKRIDALEPTLKAWVHLDRDAAARVA
VQRDIEAREGRFMGPLHGVPVALKDIYDAAGLVTTAGAGPWAHRRATVDAVSVARLRGAG
AVILGKLTTTAFAFRDPTETGNPWNPAHTPGGSSSGSGAAVGSR
>A0A6C1SXE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MPTVIRPADPRRRRIIVPVSSPLPKDVRVSFEFFPPKTAAMEQSLWGAVERLAVLHPAYV
SVTYGAGGSTRERTHATVVRLRTETALEPAAHLTCIGAVREEIDAIAGRYWEAGIRHIVA
LRGDPPEGTEVYRPMPGGYAYASDLVAGLKQVADFEISVAAYPEVHPEAASAEADLDNLK
RKIDAGATRAITQFFFDVDVFFRFLDRCRAAGITVPIVPGILPVTNFARVRQFAGQCGAS
IPDWMGDLFAGLDDDPETRKLVAASVAAEQCRALHAGGVDQFHFYTLNRADLTFAICHIL
GVRPQTVAGVTGLGLKAAAD
>A0A1G4J5T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea dasiensis|TrEMBL
MSSIRERYDSTTGPFISLEFFPPKTHPGKQNLLARMGRMTALNPLFLTVTWGAGGTTAGK
TLELATLAQRELNIPVCMHLTCTNTDRQVIDEALRAARNADIRNILALRGDPPVGEEWDQ
ASLTSEFQHAVDLVRYIKKEYADDFCIGVAAYPEGHCEGEADGTAHSALRDLPFLKEKVD
AGADFVITQLFYDVDKFLEFEELFRREVSSTLPLFPGLMPINSFLLFNRASKLSHATIPQ
HVLDRFPAESRGDDNEVRNIGVDILKEMVDEIYERTNGRVKGFHFYTLNLEKAVAQVVTR
SQYLSRILDEEKDEELVDGIEEIALDDSDVFQDDNFKKRRRKSSNAHVVPINNRVLIDTD
NENILSGRQPSGAPSRKVLVSISQGSGILGRDATWDEFTNGRFGDSRSPAFGEIDGYGPS
LKMSHQKAYAIWGQPRGISDIKKLFIRYLEGALDALPWSDLGLSPETALIQEELIQLNEK
GYLTLASQPATNSTLSSDKIFGWGPQGGYVYQKSFVEMFVPKQKWELELKPKLVPLSPIV
SYYVGDSDETFYSSLENNSSVVTWGVFPNSEVLQTTIIEEEAFKAWRDEAFSIWLEWSKL
FPRGSTPNSLLRQIHRDYYLISIVHHDFSKCDALWDLLLS
>Q4K4H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)|TrEMBL
MSKDRRYSFEFFPTKTDAGHEKLLATARQLAGYNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLQQYQAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEEDLVNFVRKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQVISDMCERLLQGGAPGLHFYTLNQADPSLAIWNNLQLPR
>I2H5Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 / UCD 77-7)|TrEMBL
MKITEKLQKNHNNLNGSSHPTFSFEYFVPKTDQGVQNLYDRIDKMYQNSLPQFIDITWNA
SGSITNISTNELVSNTQSVLGLETCMHLTCTNMDVSLIDNALKYAYESGCQNILALRGDP
PSTECTKKEGSNANIDDDTEVKQCFKYAKDLVKYIRVRYGDYFDIGVAGYPEGHPENMAK
KKKQSNHRTGNINNNSSDAEMLDEEMVEDDSGEDPEEELLLHLKEKVDAGANFIITQMFY
DADNFIDWCHKVYDIGIHIPIFPGIMPITTYSAFLRRSDWCQIKIPQEFLDVLEPIKEND
QLVRKVGVDLIAGLCQRILKAGVVNHLHLYTMNLESPSIMLLSKLNLLPTEEDTYIDNKA
IANDVVSNGNELNIYPWRKSLNPKRKNEQVRPIFWKSRLYSYIARTSNWQNDEFPNGRFG
DSSSPAFGDLDLCGSKLIRQSNKKSIELWSKPVSIDDIGKLVNNYLTGKLSCLPWSDIPV
NKEIEGILGHLTELNNKNIITINSQPKVNGIKSNNKIFGWGPTDGYIYQKQYLEFLLPRN
KIAKLSEELNCKQRNPHCILTYFSVDNFGKLATNQPDIQSSTNVTTKSNCVTWGVFPGRE
ILQPTIVEKYSFLAWKEEFYKILEEWKLKLYQAEALESVSLLQHLIDDYVLINIVDNDFV
DPEDKIFKLLISL
>E4TPQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marivirga tractuosa (strain ATCC 23168 / DSM 4126 / NBRC 15989 / NCIMB 1408 / VKM B-1430 / H-43)|TrEMBL
MKVTEHINNAKSTVFSFEILPPLKGQNIKALFENIEPLMEFKPPFIDVTYHREEYVYRDK
GNGLLEKRTTRKRPGTVGICAAIKNRFDIDTVPHIICGGFSKEETENALIDLDFLGIDSV
LVLRGDPIKSENKFVPDPNGHAYAIDLMEQVVDMNNGRYIDEELQSATPTDFCIGVAGYP
EKHFEAPSMKSDLKILKQKVERGAEYVVTQMFFDNQKYFEFVKLCRAEGIDVPIIPGLKP
ITSLKQMTALPRTFYLDLPDALVDELEKCKDNAAAKEVGIEWCIQQSKKLIEFGAPCLHY
YSMGKSDPIYRIAEGIF
>A0A4R6G778|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salegentibacter sp. 24|TrEMBL
MKITEHIKKAKGRSLFSFEILPPLKGQNIQSIYDGIDPLMEFKPPFIDVTYHREEHVFDE
RENGLLEKRIVRKRPGTVGICAAIQSKYGVDAVPHILCGGFSKEDTENFLIDLDFLGIQN
VVALRGDAIKSETYFTPDPKGNKFAKDLVEQIMELNKGNYQDEVIEQGHKTNFCVGVAGY
PEKHMEAPSLDKDICRLKDKIKAGAEYVVTQMFFDNSKYFQFVDKCRENGIKVPIIPGLK
PLATKRQLSIIPHRFHVDMPEDLIHEVENCKDNKEVRQVGIEWGIHQSKELIKAGVPVLH
YYSMGKSTNIEKIAEAVF
>A0A7R8YX16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hermetia illucens|TrEMBL
MHAPSVDFPSFPPDGNIVNLANLAVPSSYSQLKIVDLIQEKINAREYFYGIEISPGLQQV
LNYNLLKVAPLFTSIVWLASHNWAMESLDEAPAVRLAKRVEPNGPVLAHISCYNLTYDKL
RKFLKPSINNVMVVRGDDVDEGQQYRHAADLVREIRKIRKDDICISVGGYPEGHPESTSM
EDDLKFLKSKVDAGADLIITQLTFNEEALIEFIKSCRKIGITIPIVPGIYVPKSWAGLKF
VSEKTHVKPPEELYVQYESRKHNQTEFREFAVQQAVKMIHSLFESDLGIYGVQFFTLNYF
KNVYNIVQQVM
>A0A7X3LJ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. HJL G12|TrEMBL
MKPDLRKALDTQVLVGDGAMGTFLYQMGFPVGISYEELNLVSPEVIRDVHRRYIEAGAQI
LETNTFSANFDKLSKYGLETQVNEINRAGVRIAREAAGENGYVVGAIGSIRGGKRTNVST
TELKKFFEQQLQAILNEGVDGILLETFYDVEELALALSITRRLTDSPVICQFAVEDVART
LDGYTMPEAFRIMQQEGADVIGFNCRTGPNGIMSAVKTLEGHLPAPMSIYPNAGVADYVD
GEYHYGAGPEYFGQMAVKFADLGSRIIGGCCGTTPAHIAAIAGALENYTPQHFVYEPIPE
QTAPLVIHEHLQQDEDSPVDREPNLVDLVKQRHTVIVELDPPRDLDIAKFMQGAERLKQA
GADALTLADNSLAVTRMSNMALGHLVQAETGLRPLVHIACRDRNLIGTQSHMMGFDALGI
NHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKAKFVVGAAF
NPHGKHLHKAVARLERKIAAGADYIMTQPVYDPELIRAVGEATSHLDIPIFMGIMPLASG
RNAEYLHNEVPGIQLSDDVRGRMAGLEGEEGRAMGVQIAKELLDVAMDHFNGIYLMTPFM
LYEMSAQLIEHVWARSGRQLSPLFR
>A0A8H4KM35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium austroafricanum|TrEMBL
MHIKDMLNDAQKGGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWLKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVADMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTVQDIAHLFVRYLQNEIESLPWSEAPLTSEADEIRDGLIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPGIFDKMIARIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPAIPLSESV
ANGGVDTEPVANGTPATAVAN
>A0A855RD14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pumilus|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVRRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKTAAGSAYVLGTIGGIRTFNKNAYTIEEIKR
SFREQLYILLNEQPDGLLLETYYDMEEAKAVLQIARKETTLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPILENSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHIHAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELATKKRTIIVELDPPKKLNFEKFLVAANELKNAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGVMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMAKAGEDKEKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKESNTHVNYH
>A0A1F9M4W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYD12_FULL_50_9|TrEMBL
MPEKNSSKLGRILSDPGRFCLTFELVPSRGGRSKAHSLALDFARRLAADGRIQAVSITEN
AGGHAALSPEVLGKEIRDMGLDVIVHFSCKDKNRNQMESLLFAWDRIGLHNLLVITGDYP
KEGYRGVPKPVFDLGSVHALDLISRMNQGIFWSKAEKTHASPPKPTSFLKGVAVSPFKHL
ESELMMQYFKLHRKLAAGADYVITQVGFDARKFHELLLYIRRHDLNIPMLGNVFVPNMVV
AGLMHRGEIPGCVIPDALYAIMQQEAASPDKGKKARLIRAAKLLAVLKGMGYSGAHIGGP
GLSYDDMDFLLTSSEHYAPQWRELIGDISFGHPEGFYYFEKDAASGLNLPIPTVRSSAIQ
GKQIGFILACHMHQLFFNEQGLFFSSLKSACLTLEESRLAHSLDRFEHLIKFLGFGCRNC
GDCTLAELAFLCPQAGCAKYLLNGPCGGSCDGWCEVYPGKRRCFFVRVYERLKSVKLEDG
MAKGFVPPRNWALNQTSSWVNFFERRDHTGADK
>A0A847BHL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonadaceae bacterium|TrEMBL
MSTTYPLGISFEFFPPNTEVGREKLVGVRDTLAARKPRFFSVTYGAGGSTQGRTLSTVNQ
IREAGITTAPHLSCIGSEKDELRDLLAQYREQGIDSLVALRGDQPSGMGGVGELRYANEL
VEFIRTETGNHFEIAVAAYPETHPQAPNFEQDLENFVRKVKAGANLAITQYFFNADAYFY
FVERVRALGVEVPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDNQAIADYG
TEVISRLCRQLLDGGAPGLHFYTLNQATPCLRILDNLD
>A0A1M2YP21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. 63-7|TrEMBL
MSQPLLSSSDAARIRLSFEFFPPKSEEMAGQLWSTVDELAAWQPEFVSVTYGAGGSTREP
TRSTVERLLRHTSLSTASHLTCVGATREEVAQVVDDFRRIGVRHFVALRGDPPDGAGAAY
RPHPGGYANAAELVAGLRAIDDFEISVSAYPEKHPESADVAADIDMLKRKVDAGATRALT
QFFFDNDQFERYLEKVRAADIRIPVVPGIMPIQNLQQLKRFAGACGAGIPAAIDARLAHL
DADPAARATVAAELAAEQMADLYRRGIHEFHIYTMNRAPLTNRALRMLGLRPASTAAGAA
A
>R0JRL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anas platyrhynchos|TrEMBL
SRELTMVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQ
DSGDRWFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIA
NTAVNYCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFN
YAVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYESDLKHLKEKVLAGADFIITQLFFRS
ETFIKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAA
IRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSA
HPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSP
REELLKMWGEELTCEESVFEVFTCYISGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEK
VNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYE
SRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIE
QWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQ
>A0A1C5UC90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Collinsella sp|TrEMBL
MHVDDIFTKAHAAGKIPVSFEMFPPKGELTLDKAHDAAKKLSAYGPDFISVTCSAGGGGN
FAQTAAIASMLESEFNVNSVAHLTCISLTQEGLKERIAQYKAAGVENVLALRGDRPTKDS
PLYGAPSDFSFAAQIIPALIEAGFCVGGAAYPEGHIECESLETSIEHLKLKQDAGASFFV
TQLFFDNEYCYRFLDLAEKSGITVPITCGIMPFVSKQQITRMVLMCGASLPSPVIKLLAK
YDDDPASLAQAGIDYACRQLQDLKEHGVDGLHVYTMNRPSVASAAMQALGR
>A0A193LHR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia oceani|TrEMBL
MTNPDPSKQPRVSFEFFPPNTEKMEETLWASIERLSVLSPHFVSVTYGADGSTRERTHAA
VARIMKETSLTAAPHLTCIGASRDAIDDIAREYWDMGVRHLVALRGDTPKDCQSYAPRAD
GYAYAADLVAGLKRVADFDISVAAYPEVHPEAPNPDFDLDNLKRKLDAGASRAITQFFFD
VESYLRFRDRCAAAGVDSQLVPGILPITRFPQLQRFATACGATVPDWLHERFDGLDDDAE
TRQMIAASVAIEQVRLLRTQGINEFHFYTLNRSELTFAICHALGVRPQQVAA
>A0A0Q4DVF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf10|TrEMBL
MIPTISDLEEARRALDAPLFADLAGDCAVSFEFFPPKTDKMEAALWETVRALEPLAPKFV
SVTYGAGGSTRERTHATVARIARETSMPAAAHLTCVEASKAEIDQVAEEYWQAGVRHIVA
LRGDPPTMGQKFVAHPDGYENAAALVAGLQKLHPFEISVAAYPECHPDSEHQTADLDNLK
RKIDAGATRAITQFFFTPEAFFRFRDAAAGAGINADIVPGILPVSNVGQVRKFAGLCGAS
IPPWMDRLFEGLDDHPGARQLVAATVAAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GMRPKATLVAAAA
>A5LM01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae SP6-BS73|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A0U1I9D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia mollaretii|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLRDIAADYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A841HMR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Povalibacter uvarum|TrEMBL
MSVEQLKDRIGNGLAKLQGRPTVSFEFFPPKDEQMEKTLWDSIQRLSPLQPRFVSVTYGA
DGSTRSRTHNIVTRIQETTSLTAAPHLTCVGAPREEILDIARNYWAHGIRHIVALRGDPP
QGTTKYVAHPGGFAYAVDLVRGLKSVADFEISVAAYPEVHPEALGGQFDLDNLKAKLDAG
ADRAITQFFFDTGCFLRFRDQCAAAGIKASIVPGILPITRFPQLQRMARTCGASVPDWLA
DRFDGLDEDPDTRRLIAAAVAIEQVQALEREGVSEFHFYTLNRSELTYAICHALGVRPAP
SLAAAG
>A0A6H1KV38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. RLB1-33|TrEMBL
MDVEHFRALLHSVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLATRLTAH
GCRVVPHVPARLLRDDAHLKDVVDRLREAGVDDVFVPAGDADPPAGAYDGALPVLRRLSE
LGSPFAHVGITGYPESHPLIHDDLTIQAMWDKRAYATYIVSNLCFDPRVLGDWVGRIRRR
DITLPVHVGVAGPVQRAKLLSMAAKIGVGESTRFLTKHASWFLRFATPGGYSPERLLARS
AGALSSPSAGVAGLHLFTFNQIAETERWRCAVLDRLAGQGLSGGSGRRRATAPHQRR
>A0A8J8HE75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoactinospora sp|TrEMBL
MTFQVVCEIEPPTTPDLKKVRHQIGTLSSIASSFLIPDNHIGRATVSSVAVAHEVEMMGG
RSIACLNSRDRNLLGFQRDLLTAAAYGVDQFLFVYGDKPTSGNRTSDLTVRSMIEEARAF
DPAFRVGAAAGLKPLPAFKRAADFLFVQASFSLDALLRWRSENPVDVPIYAGVLVLASHN
HARRLAAAIPDIDIPDSLVEALATDRMAGVEAACELVTSIQESGAFAGVHLIPVSRYRDV
ESRLSRSLRA
>A0A7T0DVZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter mori|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFRQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A0C5BV39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilus piranensis|TrEMBL
MTIRYEANPPKILPDVNTDESIKKFVDRIKIISKKCDAIHLTENVLGYQRASPLDVGKII
KNEMPNLPITVSLRVRDKTEEEISDFVEKCIDIGFSGILILMGDPSQTGKKDSGQIPSLT
VKKLRERNIDSKIDLYLSVPNKPNFSKLEKKFDAKPKGFMTQVVQNVQQVQELSNKLKGF
AVIPIILFPSQKNEKSAAFLNLDLESYSQEFEELLKKAHEITGDILITSPNDFSGLNEFL
NEFAI
>A0A1W9WNE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_87|TrEMBL
MSHESQLKNVLVQGEFAVTAECGPPKGADPEVILRKARLLKGMVDAVNVTDNQTAIVRMS
SLAACALLKTAGLDPVLQMVVRDRNRISLQSDILGGSALGIRNVLCLSGDHQIFGNQPQA
LGVFDLDSIQFVQVVKGMRDDGVITGGDSLDHKPDMFIGAAANPFADPLGFRIVRLAKKI
KAGADFIQTQCIYNLDRFETWLSMAADRGLTEKAFILGGVTPLKSAGMAKYMKNRVAGMD
IPDDVIKRMEGVPEGKQREEGINICVETISRLKELKGVSGVHIMAIEWEEAVGKIVKRAG
LYPRPAFCKA
>A0A4R6V323|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinorugispora endophytica|TrEMBL
MLASPTRSASHGVNPRPRHIHELLAAGEPTFSFEFFPPKTPEGERKLWRVIRELESLRPA
FVSVTYGAGGGTRDRTVDITERMATDTTLLPVAHMTAVNHSVRELRHLIGRFAGAGVSNM
LALRGDPPGDPLGEWVKHPEGLTYAEELVRLIKESGDFCVGVAAFPYKHPRSADIDSDVD
FFVRKCRAGADYAITQMFFEADEYLRLRDRVAAKGCDVPVIPEIMPVTRYATIARSEQLS
GAPFPAHLAAEFDRVADDPAAVRELGVEHATKLCERLLDEGVPGIHFITFNQSTATREIY
QRLAGAPRAAAAAGARP
>A0A3B9UA55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp|TrEMBL
MKVVELINIHKDKKNFSFEVLPPLKGTGTGKLFATIDKLKEFDPLYINITTHHSEYVYRE
LDNGQFERMRIRRRPGTVAIAAAIQQKYGIPVIPHVICSGATIEHIEYELLDLQFLGIDN
LLLLRGDKAKDDRVFTPVAGGHAHTTDLIEQVNRFNSGYFADGSAIKVPGTPFGYGVACY
PEKHDEAPNMEMDMGYLKMKQDMGAEYAVTQLFYDNSKYFDFVDKARAMGITIPIIPGIK
PLAKLSQLTVVPKTFHCDLPQELAAEVKRCKTDDDAKQLGIEWATHQCQELYAHGINNIH
FYTVSAVDSVAEVTRRLI
>A0A258WU74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium 16-39-50|TrEMBL
MKITDHIKNAKGKTLFSFELLPPLKGQSIQGIYDAIDPLMEFKPPFIDVTYHREDYIYKQ
HESGLLEKVSYRKRPGTVAICASIMNRYNVDAVPHLICGGFTKEETENTLIDLQFLGIDN
VLVLRGDARHADSGFIPTPGGHAYATELLEQVANMNNGVYLHEDYDTAYKTKFCIGVAGY
PEKHFEAPNMKTDFGFLKKKVEMGAEFIVTQMFFDNSKYVEFVALCRENGINVPIIPGLK
PITSSKQLISLPKIFHIDLPEELSEAVQKCKSEKEVREVGIEHMIAQCKELMKVGAPVLH
FYTMSNPGPTKRIAEAIF
>A0A258XFP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp. 24-45-7|TrEMBL
GDVPSGEVSAGDFKYAAELVEFIRAETGDHFFIEVAAYPEFHPEAKTPTADLQNLKRKMD
AGANSAITQYFYNSDAYFRFVEQCDSFGITMPIVPGIMPINNITQLARFSNVCGAEIPRW
LKMRLEEYGDDMASIRALGIDVVSELCETLMVWGVPSLHFYTLNQSATISTIINNIKD
>A0A1W9WPB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_87|TrEMBL
MKLSTYFDKGEFVVTGEVGPIKGAIPRDRAIVPRCAQEAEALHGRVHAINVTDNQSAVMR
LGSLAASVGLKARGHEPIYQLTCRDRNRIALQSDILTAYSLGVDNMLLLTGDHIKLGDHK
TTKPVFDLDSVQLIKMARGLMEGHDIVGNEIENSPDFTIAGVVNPNFLPLDLQLMKMKSP
QMGNFMNKNVSGITVPQEWIDEIGSVDKSDRKKKAAEMMGRFIKKHKNKFQGVHIMPLGW
TDIVPHILDEAGISVNGVGK
>A0A660NV18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp|TrEMBL
SFEVLPPLKGNGTAQLFRTIDRLREFCPSYINITTHNSEYVYRQLDNGQYERDRIRRRPG
TIAIAAAIQQRYAIPVIPHIICSGATIESIEYELLDLQFLGIQNLLLLRGDKARDERMFT
PTPNGHAHTTELIEQVNRFNEGFFADGTPMKHPGESFEYGVACYPEKHEEAPNLDMDIDY
LLRKQQLGAKYAVTQLFYDNQKYFDFVEKARQKGVTIPIVPGIKPFAKLGQLTVIPRTFH
CDLPTALASEIVKCKTDDDAKALGVEWATQQCRELYAKGVPSIHFYTVSAVDSICEVAKK
LL
>V7BIY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaseolus vulgaris|TrEMBL
MKIIDKIHEAAADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANKMQNIVCVDTMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVKHIRAKYGDYFGITIAGYPEAHPDVIGSDGLATAEGYQKDLEYL
KSKVDAGADLIVTQLFYDTDTFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPADIMSALEPIKDNEEAVKSYGVHLGTEMCKKILSHGIKALHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPTNVFRVKEDVRPIFWSNRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALTDYQFMRPRSRDKKLIEEWVVPLKSIEDIYERFKMYCIGKLRSNPWSELDGLQP
ETKIINEQLERINSKGFLTINSQPAVNGEKSDSPTVGWGGSGGYVYQKAYVEFFCSKEKL
DTLVDKCKDRTSLTYMAVNKEGSWKSNVGQTDVNAVTWGVFPAKEIKQPTIVDPVSFNVW
KDEAFEIWSRGWASLYPEGDASRKLVEEVGGSYFLVSLVDNDYINGDLFAVFADF
>A0A3Q1JM86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabas testudineus|TrEMBL
MVWWALKCDFNFNLTLILSSVCTVRLILLFPSVELDIMVNQVQRGGGSWQSCKSDSSGAS
NSGGESSKESSRCSTPVLDADRLDRLRDKMRRRMESGDRWFSLEFFPPRTAGGAVNLISR
FDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQTKEKIS
GHLAKAKHLGLKNIMALRGDPIGSDWEEEEGGFNYAVDLVKHIRSEFDDYFDICVAGYPT
GHPEAQSYDEDLQHLKEKVDAGADFVITQLFFRADTFLKFLDDCRANGITCPILPGIFPI
QGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRNYGIHQAVEMCRVLLDSGRVPGLH
FYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQ
DWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLQMWGEELMNEESVYEVFTCYI
TGQPNRSGHKVMCLPWNDEPLAPETNLLNDELEKVNRRGVLTINSQPNINGKPSTDPVVG
WGPAGGYVFQKAYLEFFTSSENVDALLQVLKKYEPRVNYHMVNVHGRNMTNATDLQPNAV
TWGIFPGREILQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLV
NLVDNDFPLESCLWQVISDMFELLDAPPEPLTDRAV
>T2KH03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1)|TrEMBL
MKVTDHIKQANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFKPPFIDVTTSREEYVYVD
KGNGLLDKRITRMRPGTVGICASIMHKYKVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VVALRGDARKDESYFIATEGGNHFASELVEQISNLNQGKYLHDDIKVEHNYDFCIGVAGY
PEKHMESPSLNTDLKRLKAKVDAGADYVVTQMFFDNQKYFDFVEKAREIGITVPIIPGIK
PLAVKRHLQILPQVFKIDLPEDLIDAVERCKDNKAVRQVGIEFAIQQSKELKAAGVPFLH
YYSMGKSDNIKAIASALF
>A0A7C9VAM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium zhangyense|TrEMBL
MNPPRPPQIDENPAGIDLPLDRLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
GAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLSTPPQ
LFLGAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMERARDLGLTDKVF
VLCGVGPLASAKTAKWIRSNVPGIHIPDSIIARLEGAQDQKKEGKQLAIDIINEVKEIPG
VSGIHVMAYRQEEYVAEIVDESGVLKGRQPWKREVRRDDQLVADRLDHLLHDNVTETQVD
MVKTAH
>A0A8C6RJR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nannospalax galili|TrEMBL
MNHGKVKVLPAGHHYPTLGMWASEAGCSRLSVPPSVSRNPAMVNEARGSGGPNPRSEGSS
SGSESSKDSSRCSTPSLDPERHERLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISMF
DQMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAINYCGLETMLHMTCCQQRQEDITG
HLHRARELGLKNILALRGDPVGDHWETEEGGFSCATDLVKHIRSEFGDYFDICVAGYPKG
HPEAGSFEEDLKHLKEKVSAGADFIITQLFFESNTFFSFVKACTEMGISCPILPGIFPLQ
SYTSLRQLVKLSKLEVPKKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHF
YTLNRKVATMEVLKRLGMWTEDPKRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQD
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRNELLKMWGEELTSEESVFEVFEHYLS
GEPNRHGYKVTCLPWNDDPLAAETSLMKEELLRVNRLGILTINSQPSINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVQALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFAGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRQT
>L0F4N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfitobacterium dichloroeliminans (strain LMG P-21439 / DCA1)|TrEMBL
MDNRFKQSLLDPNTLSITWELVPGRGAREKAQENALLAAEQAAQGGKVHALTITDNPGGN
PAILADYLGQEILKLGIEPLVHFTCKDKNRNQMESQLYALDRAGVRNLLVMTGDYTVSGF
QGRPKPVFDLDPTHTLELITQMNEGLGVPGPKGMSYHQPSDFFSGAAVSPFKATEAELMV
QYYKLKKKVASGAQFIVTQLGYDVRKIHEVLQFMKLNNLNVPLVGNIYVLPFGAARIMNQ
NQLPGCVVTDKLLAEIDKERGAEDKGLSARLLRAAKMYALMKGMGFSGVHIGGHNLKYEQ
VEYIITKGEELSKEWMALIPEFDYPMPNGFYYYEKDPQTGLNTSTPVNRKSLPLDAPVGV
AYSGMRMMHSMLFTPNKNLFPVMRKIYKGRKDNRKHSLEHLAKVITNDCKDCGDCAMFEL
AYLCPMSQCPKNQRNGACGGSYQGWCEVYPNEKQCVYVRAYARLKKYGEEGDLDSHHIPP
ANWDLYQTSSWSNFFLGKDHSGKILGIPTPEEEAQK
>A0A3A6KM44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium AF36-10|TrEMBL
MNLREYLKTTNLITDGAFGTYFAAKYQTQDIPELANITATEKVKKIHEEYLNAGAKFIRT
NTFASNTETLQEDFAEVEKNIQAAVEIARDAVNGRDAWIAGDIGPIPVNGAEDAAAAADE
YYQIAKTFAECGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIGEMSLWDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLSVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTKEDAARLRRIKEETGAKILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>F7K6T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 3_1_57FAA_CT1|TrEMBL
MKISELYQAKQNQGNPSKKTLSFEIFPPKKDSELKNIDKTLAVLCELNPDYISVTFGAGG
GANRNRTIELAKRIKQEYHVEPVVHLTCLHYDKAEIDEFARVLANAGLQNVLALRGDKNP
DMREKESFCHASDLIAYLKGKWDFCFLGACYPECHPESEDKVGEIRHLKAKVNAGAEVLL
SQLCFDNHAFFRFQEACRIADIQAPIIPGIMPVINAAQIKRMITMCGATFPVQFQKIIQK
YESNKEALFDAGMSYALSQIIDLLVSDVEGIHLYTMNNPLVARRICEGIRNIV
>A0A2H0AUN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG23_combo_of_CG06-09_8_20_14_all_45_10|TrEMBL
MLKGYIDAFNVTDGQTAVVRMSSWAACLIGKEEGLDPIVQMTCRDRNRIALQMDILGVAA
LGINNILCLTGDHQKFGNHPMAKGVFDLDSIQFLKVVKDMRDEKKFQCGDEMAVVPNLFI
GAAANPFADPFEFRVIRLAKKVTAGADFIQTQIVYNVDKFAEWMKHVRDRGLHEKVKILA
GVAPIKSVGAARYMKTKVPGMDVPDSIIDRLRGVPKEQVSKEGIKLCVDIINQVRQIKGV
AGIHLMAIEWEETVPEIIAAAGLLPRP
>A0A2T8F5D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides gansuensis|TrEMBL
MRNRGRARVLEGLLSRARYEVLPTADVVDEVYAGLPAGATVTVTASPAKGLAATLDVAER
LAALGFDVVPHLAARMINGPGELAEITRRLHGAGVRKVFIPAGDAEPPAGAYHSALQVLE
DLAAAGNPFTEVGITGYPERHPSIHDDVTVQAMWDKRRHATQIVSNLTFDPKLLADWVTR
VRSRDVHLPILVGLPGPVERAKLLRMATRIGVGESARFLAKNGGLFTRIAAPGGYDPLRF
LAGAAATLGRPDMHVAGLHLFTFNQVAETEAWRVAQLARLRRLGSTRADGATSAVPGRVT
>A0A3S1S0J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7D.F.Ca.US.004.01.2.1|TrEMBL
CVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGEPYRPHPGGYENGAELVAGLKAIA
DFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRAITQFFFDNDLYERYVERVRRAGI
YIPIVPGIQPVHSFRQVANFSARAGAHVPGWLAERFEGLDRDPQTHALVASAVAAEQVMD
LVERGVGDFHFYTMNRADLVFAICHMIGIRSHDAEAAGSAAA
>A0A414R671|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium ventriosum|TrEMBL
MNIADLFKKEHTVFSFEVFPPKKESGIETIFSTLNELKNLNPDFISVTYGAGGKSVANAT
TIDLCSYIKNELGVETIAHLSCLYNTKDSIDRILDQLEEKGVKNILALRGDVNPDFAIEK
DFKYASDLTEYIMSKNRGFNVSGACYPEVHQEAANMIEDIQNLKKKVDSGADHLISQLFF
DDQVFFDFQEKARIAGINVPIEAGIMPVTNKKQIERMVSMCGASIPAKLSKVLQRFGDNH
EAMRDAGISYAIDQIIELAAHGVDGVHIYTMNDPYVARRISEGVKNILKSGK
>A0A0F6H9P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans str. UI 12621|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESA
>A0A5D8Z5X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter lacus|TrEMBL
MVPISFEFYPPKTAEQHAQLDRTVGKLRAENPEYVSVTFGAGGSTLSHTPETIQKLRASG
LDSAPHITCMGGSREEIRGLLKLYRALGAKRLVALRGDLPSGMVSAGELRYADELVQFIR
EETGDHFHVEVAAYPEMHPQARDAHVDLRNFVGKVRAGANGAITQYFYNADAYFRFVDDV
RRAGIDIPIVPGIMPIQNFSQIRRFSDLCGAEIPRWVTQRMLAYGDDADSVRAFGAEVVA
QLCRRLVEGGAPSLHFYTLNLSKPTMNVLAQLR
>A0A1H9CWK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cuatrocienegasensis|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPAAPHLSCVGDSKAELRELLGLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VSFIREETADHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQRMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTDSIQAYG
EQVITQMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A2K4MRB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium sp. MWU13-2610|TrEMBL
MTQTPRTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGQAAAPHLSCVGSTRENIAAILNEYRGNGIRHLVALRGDIPSGMVGAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLDNFVRKVRAGADSAITQYFFNADSYFRF
VDEIRARGLDIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRLRMQAYYDDTASIRALGL
DVVTELCDRLLQGGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A196MW17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. TCM1|TrEMBL
MSLPSIHPNWDLPPKGMTDGFSLEITAKDIEALTEAAPAIPAETPVAVTFLPGESLEARI
AAARTVRALGFEPMPHFSARRLESGDDFETYLAAVVREAGVRRCFVIAGDPAEAAGPYAD
SMALIRTGAFERAGIRAIGIGGHPEGHPNMSTDQTFEVLTAKCGEIASRNMAPLIVTQFG
FDAAPILGWLAELRTRGIDAPVRIGVPGPAGIKTLMRFAARCGVGASTSVLAKYGISITR
LIGTAGPDKLVDALAAGLGPQHGKVRLHFYPFGGLARTVEWINDYTARH
>A0A0A8L6K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyveromyces dobzhanskii CBS 2104|TrEMBL
MATVKQRFDELKGPCVSLEFFPPKTESGKRNLLARMERMCALNPLFITVTWAAGGTTAEK
TLELASIAQRELNVPVCMHLTCTNMNREIIDQALKSARDADIRNILALRGDPAIGEEWSA
EGDSEFKYAVDLVRYIKKNYGDDFCVGVAAYPEGHCEGEADESSQDPIRDLPYLKEKVDA
GADFIITQLFYDVDKFLSFERLFRENVSADIPMFPGLMPINSFLLFNRAAKLSHAAIPKH
ILDRFPASVQSDDNRVKEIGVEILIDIIEQIHERTNGRIKAFHFYSLNLERAIAQIVAKS
PTLSKILEEEDNDEEWDSEIVLQDVDTLTLDDDNVKKRKRQSSASTDFPLNTSIINKLHG
GASSNVPAVPSRKVMISISQGTGSLGRTVTWDEFPNGRFGDSRSPAYGEIDGYGPSLKVC
NKTAYDLWGHPVCEKDIKNIFIRYLEGSMTALPWSDLGLSAETAFIQEELIELNQRGYLS
LASQPATNGSPSSDNIFGWGPANGLIYQKAFVEIFIHKDEWERVLHPKIESKNGEFSYYL
GDYTGHFETNLQPKSSNAVTWGVFPNSEVVQTTIVEEESFKAWRDEAFSIWIEWSKLFPK
NAPENSFLRKMHRDYYLVSIVHHDFNNPDGLWDMLSN
>J1F3I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus mali KCTC 3596 = DSM 20444|TrEMBL
MDKVLTKPHISFEIFPPSNNVQNTKIYQTVQALGDLRPEFISVTCNNKRLNFKDSTLRIA
SYIEKELQIPGVVHLTARYFDKGQIDYILAKLKRVGIHNILVLRGDLVPGREPKNDFKYA
TDLIDYIKQKDNSFKIFGACYPEGHPESPDKVTDIRRLQTKVAAGCDCLITQMFFSNDTF
YQFRENCALANIDVPILAGIMPIVNRSQALHVIQNSASYLPKKFIAMLNRYQTDPAALKA
TGLAYAINQIVDLVTQDVDGVHLYTMNHPDVARHIYQETETLFAI
>A0A7L8AK68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter haliotis|TrEMBL
MKITEHIKKADGKTLFSFEIIPPKKGNNINDLYNNIDPLMEFNPPFIDVTTSREEYVYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYVLVDCHYLGIDN
VMALRGDAMSHQKYFTPNQGGNHYATDLVKQISDLNCGKYLHDVIESTNKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFAFVEAAKKAGINVPIIPGIK
PIAVKRHLQLLPQVFKIDLPETLISSVENCKTNKDVRQVGIEWAIQQSKELLAAGVPVLH
YYSMGKSDNVHAIASELF
>A0A842EA02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
KEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVAEQIISQN
>A0A7J4PF82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinaceae archaeon|TrEMBL
MLFNFREKLNSSKFLVTAEISPPKGTNVSAPLEDASQLKGLADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEVIMQLTCRDRNRIGLQSDLLGAYALGLRNVCVMTGDFPSCGDHPGSKP
VYDLDSVQLLELVRKLDKGIDLAGNKLDGGTCFCMGAVSGINPQEVLQLIKLEKKVGCGA
DFIQTQAVYDVGMFEEFVESTAHLDVPILAGLIPLKSLRMAEYMNEHISGIHVPEEVLSR
LKTASDPVEEGLSIASGTIKELTKLCRGVHIMPIGSHKNTPRLLSMAGISPK
>A0A069S4R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus str. 3975 RP4|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELAGEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>R8ZZA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira wolbachii serovar Codice str. CDC|TrEMBL
MIYRAVGKYNVRELTKFIENAPSEQYLSVFVGAASRQQKVNLTIRDAYDLKTKINNNLQL
GGVVIPERHTNNSPEHLRVFDKIASGCKFFVSQGVYNLDASKNFLSDYYYYGKEHKIELA
PIIFTLTPCGSLKTLQFMHWLGISIPKWLENDLRNSDDILSKSIELSKNIWLDLKNFADA
KNIPIGRNIESVSIRKEEIDASIELLKLTE
>R9A725|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira wolbachii serovar Codice str. CDC|TrEMBL
MHISQVLGKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEQTGLTIVSHLTCVGSTKEEIRGILKRYEKSGIHNIMALRGDPPKGQSEFQKT
ENGFAFAGELVAFIKKEFPQMGIGVAGFPEGHPSTPNRLKEIEFLKWKVDQGADYICTQM
FFNNNYFYDFVERCEIAGIKVPIIAGIMPISSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDVYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRKIYESLGIRNFDSIG
>V9H5T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Simonsiella muelleri ATCC 29453|TrEMBL
MTQPKQLSFEFFPTRTPQGREKQVITRKQLSQFNPAFFSCTSGAGGSTRDGTFQTIGDIL
SEGIAAAPHLPCIGMTVGEVEELLLKYKEMGVRHIVALRGDIPSGIGLGMDGMRYANELV
ELIKNNHGDDFHIEVAAYPEYHPQARSAEDDINNFVRKAKAGADSAITQYFYNPDSYFRF
VDDVRGRGVEIPIIPGIMPIASFSKLVRFSDACGAEIPRWLRLKLQSYADDTASIKALAL
DVVTEMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>A0A4Y6UJ22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Swingsia samuiensis|TrEMBL
MLVSIELVPRSKEDLLRDITIVENILPQINVLNVPDLLRFDLRSYEAASFAYSEKKDFNV
IPHIRAIDIAPDAPLPCVDRPEIKEVLVVAGDPPPTEQHEVYPNTSVDIIKRYQKEAPHL
RVYAVFDPYRRSPKEELEELERKKEAGASGFFTQPIFDTNLLQLSMDWLRDETVFWGISP
VLGEKSRRYWERVNNIVFPKEYDFSLEGNIHFAQRMLQLVKQQNDNAYLMPLRVDLGAYL
TELQSFIVY
>A0A5C8D825|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira aalborgi|TrEMBL
MNSVENFINKLENEKEFTFTLEVTPQAKSDLGYLVEKIKSSNIEKYIDAFIIPDSPFANL
KISPILSSLQLSQRLKTEKPFIITQTMRDKNSIALQNDLIGANYFDIRMVLALTGDPVVN
GNQKQAKGVFEGNSELLIRIIKNLNEGKSAGNFIFKEPLKKIYPFCSINSYSKNDEMLKV
RLSKKTASGVKAIFTQPIYEVETLKKFLNWINEMPLKEMKLKEKPILFPGFFPVLSYKTA
YFIYYKLPGAYIPEEWLNKLKDASEKSAEEEKKVAFELSSNLFKDMLSVCKKMHIMSMNN
YDFVADLLKHI
>A0A373V811|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. AF19-10LB|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSVGMVRFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPELLKLAEI
>A0A8H7UVU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor saturninus|TrEMBL
MKIIDKIQQAQKDKQIAYSFEYFPPKTEVGFANLIDRLGRMSQLEPEFISCTWGAGGSTH
DRTLELCSTAQSLYGLDTLMHLTCTNMGKAKIDIALKQAKEAGIRNILALRGDPPRGHEY
WTPVDSQFSHAIDLVKYIRQEYKDYFCIGVAGYPEGHIDCPDKEQDMLHLKEKVDAGADF
IMTQLFYDADVCVAWIQKCRQHGIHAPIVPGIMPIPTYQSFRRMINLCNVKVPAKVMHDL
DEIKADDQKVKEYGVHLAVEMIQYLHQQAGICNFHISTLNLERSTRLILEALHLHKASES
IQPSKVSPWAPIHDPARAELWDEFPNGRYGDSRSPAYGQTTHSSGQILPTSQAIIKWGLP
ETEDDIGQLFVKYIKGELESLPWCEERLQTESDAICQRLCQINQRGYWTVSSQPAVNGAS
SLDEVYGWGPKGGYVYQKAFIEFFVAEDGIEDLLKRLGKDESITYYATNQKGDFSTNVSD
ADEAQNAVTWGVFPGKEIIQPTIIEKASFEAWKDDAFGLWREWEEQYPPNSKSQELLHAI
GQKYWLVNVVHNDFQQPDLLFDVMLST
>A0A4V2RDI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesobacillus foraminis|TrEMBL
MKFLDRLKNEILIADGAIGTLLYSFGTDTCFEELNLSHPDEIVKIHTAYIEAGADIIQTN
TYAANYLKLQRYGLEDHVKEINSSAARLARQAAAGHNAYILGTIGGNRGIRPNTISLEEI
KRSFREQLYCLLLEGVDGILLETYYDLQEIETVLAIARKETDIPLIAQVSLQESGFMQDQ
TPVNEALKRLEGIGADVVGLNCRLGPHHMITSLEQVELPKKAFLSAYPNAGLPAYTDGKF
HFESSADYFRQSARRFRDQGIRLLGGCCGTTPEHIRAFATELNDLDPVTEKKVTFKNTNI
EVKSSPVIRKERPLQEMVKERPSVIVELDPPRKLDTTRFFEGAKALKEAGIDALTLADNS
LASPRISNSALGHLVKEQVGLRPLVHLTCRDRNVIGLQSHLMGLHTLGLHDVLAITGDPA
RVGDFPGASSVFDVSSFELIEMIKQFNEGLAFSGKDLGQKGVFSIAAAFNPNVRSLEKAV
VRMEKKIKCGADYFITQPVYSEKLLLDVYEQTKHLDTPVYIGLMPLTGSKNAEFLHNEVP
GIKISQNILDKMAEFKHDPVQSKREGIAITKSLIEAAAELFNGIYLITPFMNYEMTVELA
AYAREYSDRLSRRKQNAESFTN
>A0A826HYI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei subsp. paracasei 8700:2|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A1V4VJ40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelotomaculum sp. PtaB.Bin104|TrEMBL
MLKGYVDAANITDCQTAVVRLSSICAGVHIIREGVEPVIQMTCRDRNRIAIQSDLLGAYS
LGMRNILCLSGDHQVFGNHPTARNVYDVDSIQLVNLVRRMKDDKLFFSGEAIKEHEPKFF
VGAVANPFADPFEYRVDRLEKKINAGAEFIQTQSIYDLERFSRFMESCVERGLHERAYIL
AGVTPLKSWRAARYLQTNVPGMIVPDEIVERMKNAGNPQEEGINICIEQIKYITEQIKGV
SGFHIIAISWPEAVPVIVRRAGLNCKPDALPLNDN
>A1AXB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruthia magnifica subsp. Calyptogena magnifica|TrEMBL
MKISFEFFPPRTNQAKEKLNQVRQSLSVVSPEYFSTTFGAGGTTQDATLGAVLDIQKNDN
IPAAPHLSCIGSEKSNIVELLDQYKSTNINRIIALRGDIPLGIGDIGDFHYANELVEFIR
SEYNYYFHIEVAAYPEMHPQAKNIVSDLTHFVNKIKAGANGAITQYFYNADAYFRFKDDV
QKLGVDIPITPGIMPITNYTQLLNFSNMCGTQIPKWILERLKLYENDLESLGDFGFDVVA
NLCQTLKSQGVNSFHFYSMNCAEPSLKLAKSII
>A0A0M2CY22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria sp. UCD-OTCP|TrEMBL
MPIDPPHAGPAAALLRDFSLEMTGKDVPALEEAAAVVPAGTRINVTFLGNEDLGMRVAAA
RAVREHGFVPVPHLSARRLRSQGELEEFLAALAEVGAAEHVFVVGGDPETPEGPYPDSLS
VIRTGVLPRHGVWGVGVSGYPEGHPGIDDAALWSALTDKTAAIREQGLEPEIITQFGFDK
DPVLEWLAEVRRRGVDTPVRIGVPGPAGVRRLLGYARRFGVGTSAGIVQKYGFSLTNLLG
TAGPDRFLRDLAAGLDPAVHGQVLLHFYTFGGLRATAEWVREFGTDGGTP
>A0A2D5HB66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp|TrEMBL
MTAAQRPADTPLFGELPGDISVSFEFFPPKTEKMETQLWDSITQLAPLAPNFVSVTYGAG
GSTRERTHATVSRLVRETDLVPAAHLTCVGASKGEIDEIVDQYWDAGVRHIVALRGDPPP
TDEGVFVPHPEGYTCAADLVAGLKARHDFDISVAAYPEIHPEALSPEADLDNLKRKIDAG
ASRAITQFFFSTDAYFRFMDKALAAGIDAPIIPGIMPVTSFAAIRRMSGNTEIPGWLETM
FEGLDDRPGPRALVAAVAAADLCKRLYDGGVRDFHFYTLNKAEQTYAICQLLGLRPKTNP
TETAA
>A0A4R0QHJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. X16XC17|TrEMBL
MTLPLWYTRKMETILKSTRKLKIIVEIAPPKTLDDSVFREAIKMIDRKNVSAISIPDNPM
ANPCISNLSLAASVKGETKTPFLLHLTCRDRNLIGLQSQLMGMHLLGFHDVLAVTGDPSQ
MGQLIGASSVYDVTSHQLIPLLKQLNQGRAFNGSSLGKSTNFRVATTINPNLEQDELKNS
LRNKMESGANYAITQPVFEMETVEKLLATSPDNLDKMILGLMPFSTYESALSAHQNVPGI
HLPPSYLEDLEQVKDDLAKCQEVALTHMKKLVDVILQHFNSIYLVHLPQQMEVTCQLIDY
IKAKETVCP
>I1YIU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga frappieri (strain ATCC BAA-2434 / DSM 25690 / JAM7)|TrEMBL
MAKSPIISCEFFPPKTEKGVNTFLQVATELAELQPAFYSVTFGAGGSTQHNTLDAVIAIQ
QRAATTGIDAAPHLSCVGSSRQGIRQILQTFIDNDISRLVALRGDLPSGMRDPGEFRYAN
ELVEFIRAETGDHFTIEVAAYPEVHPQAPNANIDFDNFVRKVDAGADSAITQYFYNIDAY
LYFVDRCEQAELDIPIIPGIMPINNYSQLARFSAGCGAEIPRWLSKRLEAFHDDTASLQA
FTTDFLTDFTQQLLDLDVPGLHFYTMNKTQPVLTVCERLGLLTP
>S3DH25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glarea lozoyensis (strain ATCC 20868 / MF5171)|TrEMBL
MHVSEMLAEAKQTGQPKYSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRQA
QLTCEMVSVAQSQYGLETCMHLTCTDMGKEKVDDALKSAYKAGCTNILALRGDPPREKEK
WTATEGGFHYAKDLVKYIKQSYANHFDIGVAGYPEGCDDQDDPEALLDHLKEKVDAGATF
IVTQMFYDVDNFLNWVAKVRARGVTIPIIPGIMPINTYASFVRRCNHMNASIPPEWSEKL
EAVKNDDSAVRSIGTGLVAEMCRKILDSGEIHHLHFYTMNLAQATRMLLDELNLTPSTER
PLKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELD
AYGIGLRGTNEQNRKLWGEPKSISDIANIFVNYLEQSVDSLPWSEAPITSEADVIKQDLI
ALNRRGLVEKDPELTYYSVNKAGDLKSNSPGEGPNAVTWGVFPGKEIVQPTIVETISFLA
WKDEAYRLGMDWAHCYDAGSPSRQLIEKMMNEWHLVNIVHNDFHQSHGLFPLFDGLTVQN
INKPFEATTTNGVNGTAPKSNEHLPLTNGTGNALVAA
>A0A158J5Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia telluris|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRASRAQLALLKPKFVSVTFGAGGSTQQGTLDTVLEMKQ
EGLEAAPHLSCIGSSKESLRAILGQYRENGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFNIEVAAYPEYHPQARTPKSDLENFVRKVQAGANSAITQYFYNGDAYFRFVD
EARRLGVDVPIVPGVMPITNFTQLVRFSEMCGAEVPKWIARRLESYGDDREAIRNFGLDV
VTDLCRRLVDAGAPGLHFYTLNGAAATKTICERLNLKGV
>A0A455VU58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia symbiotica|TrEMBL
MSFYHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIHRLSSLKPKFVSVTY
GANSGERERTHSIIKGIKDRTGLDAAPHLTCIDASPAQLRDIASDYWSSGIRHIVALRGD
LPPTDGGRPEMYATDLVTLLKDIGDFDISVAAYPEVHPEVHPEAKSAQADLINLKRKVDA
GANRAITQFFFDVESYLRFRDRCVTTGIDVEIVPGMLPVSNFKQLQRFASLTNVRVPSWM
TSMFAGLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGILWA
CGQWLPPDPLIMRAGRCVKATPFWV
>A0A4P7ZYU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. CB0101|TrEMBL
MAWHWIQGVLGLQQALEVGSLAITAEVMPPRGGDASSTLAHARALKGRVHAVNVTDGSRA
VMRMSSLAVCRLLLDQGIEPVWQVACRDRNRIALQADLLGAHALGIRNVLCLTGDPVRAG
DQPGARPVNELESVRLLQQLQALNQGLDPVQGALADGPTALFAGAAADPQSPSWSGLKSR
IARKHAAGARFLQTQMVMDGESLKRFVGEITGPLGLPVLAGVFLLKSAKNAAFINRVVPG
ANIPQSIIDRLAAASNPADEGISIAAEQVAAYAGIAQGVHLMAVKAEERIPLILERAGLS
SRC
>A0A2I1IQ56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winkia neuii|TrEMBL
MTTAHLYKGYKAGERTTHPTVSFELFPPRSSSKLSSIWAGVDRLIAAAPDYVSVTYGASG
AKVDTRDTSVRVLTRVLDRHPGLPAVAHLTCVGATRGQLAMTIRLLLRAGIRDFLALRGD
PPAGQTEFKVVPGGLASAAELVALIREIAADTLPDGVGTGPNGAGAASAANPKNYVSIAV
AAYPAASGQYRRNDIAALLEKELAGADYAITQVFYNPDEYASLVRELTIAGGRLPIVPGI
IPLTDLKRLNALEKIAGVAVPEEISKTLQIADARERVAKSLNATLALIDGVLAAGAPGVH
LYTFNRPRPALDVVEYVRASGYRNGRMPKRGGIDTELVDLALHRLTPSN
>A0A2T0FGM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wickerhamiella sorbophila|TrEMBL
MKISQKLERYHQEAPNDGASISFEYFVPKTSQGISNLYDRMDRMYKLDPLFVDVTWNAGG
SQSNFTTEMIHTAQNVIGVDTCMHLTCTGMPVEVVDQALEEAHKANCHNILALRGDPPRV
VPGEEKPITHFRYAKDLIKHIRDKYGDYFDIGVAGYPEGHPEEPDADVLIEYLKEKVDAG
ASFVITQMFYDVDLFLNWVDRCRAAGIYVPIIPGIMPISGWASFNRRAKWCQVNVPPQFL
AELEPISNDDAAVREKGSQLVANMCAKMIAHGISHLHFYTMNLERATIMVLEQLHMLDKN
NEKRPSPLPWRQSLGKGRESESVRPIFWRNRKHSYVSRTADWDEFPNGRWGDSRSPAYGE
LERYGVLLRQSTQKAIELWGSPKSLEDLGQVISKYLSGKLPCLPWSDDPVGAEISVIREK
LLDLNSRGFLTINSQPAVNGVHSSDPIHGWGPKKGYVYQKAYLELLVPKERFEHIKPKLD
SDEYVTYYATCFRGCHVTTNASSDEPNAVTWGIFPGQEVQQPTIVERGSFLAWKDEAFRL
AFEWAACQPKDSDSYKFLTSLSRGWYLVNIVHNDFQDPDAVFRIFE
>A0A2T1AR91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia insulsa|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWVEVAGYPEYHPQSRSPRHDLENFAHKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCQRLIDAKVPGLHFYTLNGAAATKAICERLGA
>A0A0K9I5K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocarbo indianensis|TrEMBL
MNRFSQALKEKDFVVTVELEPPKGTDLEPLVKLASDLAKRVDAVVLADNPRAEARLDPVM
AAHKLLRHAEVDVILTLTCRDRNRLALTGQMLAAAAAGVESLLLVSGDFVNLGDHPQAKP
VYDLDSVQALQLAAKLSQGQDLAGGEISDPPAFLLGAAFSTQAEPRGAHLMKLKKKLRAG
AGFIITLPLPEAAPYAPLRAETGEAKLIAGVTLADPAERERAAALVKELQAAKADGVHLA
LPAAQAELPAFLNACGL
>H2AZ13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 / NRRL Y-8276)|TrEMBL
MSLLDAYRLRTEPSISLEFFPPKTESGKTNLLERIERMSVLEPTFITVTWGAGGTTADKT
LELAGLVSQHLAIPVCMHLTCTNMDPEIIDGALERCRSLGIKNILALRGDPPIDLDDETG
IHFSYASDLVQYIKNKYRSEFSVGVAAYPEGHPSENDEVQDVTKDLVHLKQKIDAGADFV
ITQLFYDVEKFLTFEKLFRERVSETVPIFPGLMPINSFVLFNRSAKNSHASIPTKIIDKF
PVEIQNDDNAVKSIGVDILMEIIQEIFERTDKRVRCFHFYTLNLEKAIAQIVSQSSILSY
IIDESEDEYDNALIDGNGSNLDSSEFLVKNLSINGDDDSDDVRKRRRRSSVVSAELIHNR
VIVDKSENQRENMENVSGGLPSKKFVVSISKGSGILGRDATWDEFPNGRFGDSRSPAYGE
IDGYGPTIKVSNKRAYELWGTPKNIKDLKNIFIKYLEGSIEALPWCDLGLSAETALIQEE
LIQLNQRGYLTLASQPATNASSSTDKIFGWGPANGLVYQKAFVEMFVHRQKWESMLKPKL
DHYGLRKVSYYAGDSDGLFDTNLDGHSSNVVTWGVFPNSQIIQTTIIEEESFKAWRDEAF
SIWYEWSKLFPRNTPTNTFLKQIYSDYCIVSIVHHDFIEIDELWEILLD
>A0A652YYG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia globerula|TrEMBL
MTFDAVRGRSSDGWASRTPSIVDRITSSTGSRIPFSVEFSPPRDAEAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSIDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPDGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
HDTKYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAFDPEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGSQENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTSDVSTDSQASV
>A0A0W8DFB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora nicotianae|TrEMBL
MGKIIESIRSAYAARADDASARPTVSFEFFPAKTNAEGGLSNAVDLIKLIREEHGDYFCI
ACAGYAEVHTESWNHPDLPPSNEARALDLQRLKAKQDAGADFIITQFFFDVDNMIQWISD
CKDAGITIPILPGYLPIQNYSSFCKFTSWCKTRVPEKVLTALDAIKNDDAAVRRYGTQLA
VETCRRLLAAGVNSLHFYTMNLATTVTQVLEGLQLLPARNQRELPWQSTLQRSTVEGEQV
RPIFWSNRQASYIARTAAWDEFPNGRWGDRTSPAYGELSEYYLAFKRPKLQRTELWGTPQ
TEEDVWNVFVRFIDGHVKQLPWCEQALSLESAAIRENLQWLNSNGFLTINSQPRVNGAPS
SDPSVGWGGDDGVVFQKAYVEFFVAPEKIAHLVKVMRRDYPQLSFHALNRRGDEHRNTPL
HSVTAVTWGVFPGIEIVQPTVVDSDSFAAWKDEAFELWQTQWASAYPEGSCSREVIQHIY
DSYFLVNIVDNDYANDDSDIFSIFTRIITEAMDKEELRTRVLELEARREKMFDTLASFQS
LQKDLNGELRAAHSELAGVRGENLQLKEKVRQLEAQLALASL
>A0A8J6DD01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Galemys pyrenaicus|TrEMBL
PLTPCPPPPCSRRSAMVNEPRGGGGPSPHSEGNSSGGESSKESSRCSTPGLDPERHERLR
EKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKE
TSSMAIASTAVNYCGLETVLHMTCCRQSRDDITGYLHKAKRLGLKNILALRGGVRQHFRS
GALPSRRPLPSLQGSFPFSGPTPSTRRAPPGQQQQQALWVVRTVGPAAVEPRLDFLTSPQ
FSEESSRACPGSVLHRSSSIAGSACSWPNQRARRWAVAQEREQLLMPLVRVFGPHNPVGD
HWEEEEGGFNFAVDLVKHIRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGAD
FIITQLFFEADTFFHFVKACTDIGITCPILPGIFPIQGYHSLRQLVKLSRLEVPQQIRDV
IEPIKDNDAAIRNYGIEQAVTLCRQLLASRSVPGLHFYTLNREVATTEVLKRLGLWKEDP
RRPMPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDY
YLFYLKSKCPREELLKMWGEELTSEESVFEVFAHYLSGEPNPSGYKVTCLPWTDEPLAAE
TSLLREQLLHVNRQGVLTINSQPGVNGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRKTVE
ALLQVLKNYEPRVNYHIVDVKGENLTNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFW
KDEAFALWLEQWGKLYEEESPSRRIIQRIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELL
RRPAPGDGEADAAP
>A0A7V3PYA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MNFKEKLRSGKFLITTEIGPPKGIETEKILKEAELIRGRVDAINVTDLQSSVMRLGSLVV
CMLLKQRGLEPIFQLTCRDRNRLALQSDLLSAAAVGIENVLILTGDHPKLGDHPDAKPVF
DLDSVQLLQVVSQLKKGSDMRGNKLEGRPPEFCVGAVVNPGAEPLEPQIIKMEKKIEAGA
EFFQTQAVYDIPTFERFLSKVGHLKVPILAGIVLLKSAQMARFMNKNVAGVYVPEELIIQ
MQEAKDKIAKSVEIASRLIKELKNMCAGIHIMPIGWNEVLPRLLDEAGL
>A0A6L9FTM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. V32_P6A28T40|TrEMBL
MGYTHASHIDALNQSIAEVSDINVSFEFFPPSTPQMEETLWSSVHRLKELKPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDASREELITIADDYWHNGIESIVALRGDI
PPGGGKPEMYAADLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDIESYLRFRDRCVAAGIDAEIIPGILPVSNFKQAARFAAQNHVKVPQWMAKQFAG
LDDDPVTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPIAVA
>A0A351IAI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MALCEKIKSGKFIITSEIAPPKGTDVEEILKDAELVRGRVDAINVTDLQSSVMRTGSLAM
CKLLIERGLEPVFQITCRDRNRLALQSDLLSAAVFGIQNVLALTGDHPALGDHPGAKPVF
DLDSMQLLEAIRGLQSGKDMAGKELKGSPKFCVGAVVNPGADPIEPEIIKMEKKIDSGAQ
FFQTQAIYEMHLFEKFLKASSHLKTTIIAGIVLLKSAGMARYMNKNVAGVFVPEDLIQEM
EQTKDKSAKSIEIAARLIKELKPMCQGVHVMPIGWDKKVPLVLDAAGL
>A0A1M7MUU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium chilense|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNSFAIDLVRQINDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFNFVEKAREMGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNVEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A438BD96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus agglutinans|TrEMBL
MTFDAVRGRNSAGWVTQTPSIVDRIRSSDGGRIPFSVEFSPPRDEAAEERLWRAVRAFER
LNPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVGHSIDELRAMCGAYADRG
ISNVLVLRGDPPGDPLGEWVKHPEGVEYAEELVRLVRDMGDFHVGVASFPEGHYRAPDLD
HDTKYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVVAYDPEQGEKPIIPEIMPITSLRSA
RRSLELSGSRLPVELDERLRRAAGDGPEENRAAVREIGIEVATEMAERLISEGAPCLHFI
TLNFARATGEVLANLGMSASAAV
>A0A1Q7IYM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_1_40CM_4_65_12|TrEMBL
MGLNDETSRQSLIGLLRAPRYEVLPTDDIEQLVLTHVPHDVTMTITASPRRGIDATISLA
ERLAKHGYHVVPHISARLIRDDAHLREVLARVDALGRGEVFVIAGDAKEPAGDFPDSVSL
LTAITAETHGLREIGVTGYPERHSFIEDDLTIQAMWDKRRIATYIVSNLCFDPRIVKKWV
ARVRRRGVQLPIHVGLAGVAEPAKLLRVSTRIGLADSARFLRGHSNWFMRMVQPGGYDPE
RFATGLLPDLAAPERRVVGLHFFTFNEIEATERWRQDALSRLLVA
>A0A4R0FGT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 3781|TrEMBL
MTKRVPISFEFFPTKTDVGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGNHFTIEVAAYPEMHPQADSFDRDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDAASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A1F1LP41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Abiotrophia sp. HMSC24B09|TrEMBL
MTQPPAPFHHPSLSYEVFPPNTQVGAERLTHTLNDLAELKPDFISVTCSNRQPNIEETTL
KVANHVQNTLHIPTIAHLPAMYLSKERVAASLDSLDQLGIRRVLALRGDILEGLEPVGDF
SYAEELIHFIKEGKPHFDITAACYPEVHPDAPNAVADVRFLKRKVDAGVDRLITQLFFDN
DCFYHFQEKCALANIEVPILAGIMPIVNRNQALRLLTTCETTKLPRKFKAILDKYEHEPQ
ALRAAGLAYALDQIVDLITQGADGIHLYTMNQSDTAHYIADAAKALFK
>A0A2T7PTH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pomacea canaliculata|TrEMBL
MATVSREKQLKGDPEALTVGNFNSSPVTSRPSSPSLWSPTYTRLIDRIHRRKVSGDKFFS
LEFFPPRTANGAINLISRFERMNRGKPLFCDMTWHPSGDPCNTDKPTSSTCIAGTMLNYC
GIETMLHMTCVHQTRHRVIENLGKAKDLGIRNILALRGGYPSGHPECTSYADDLQHLKAK
VDAGADFIITQLFFKAESFLKFVKDCRAIGINCPILPGILPIQAYQSLRHIVKLSRLEVP
QEIIDAINPIKENDEAIRNFGIDHAVQLCKTLLEAGDTDPETTVPGIHFYTLNREVATVE
ILKKLGLWAEDVLRPLPWKLTANAARCKEEVTRMPWDDSELIAETMLIAEKLACINCRGV
LTINSQPRINCAPSEDPSVGWGIPHGYIFQKAYLEFFTSRENVEALKTILPSYPLVNYHI
VDHNGEADYTNCDESQPIAVTWGVFPGKEIIQPTVVDPVSFKSWKETCLWELVDKMLTLA
ASIAGSKSNSTSELAFSESPQS
>A0A345H9N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium arcticum|TrEMBL
MKVTEHIEKANGKSLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEYKE
LPSGLLEKRIVKKRPGTVGICAAIQNKYKVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VLALRGDAVKSEIYFKPEKEGNQFASDLVTQIENLNKGLYLDEYLQNTSATNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGATYIVTQMFFDNKKFFNFVAKCREEGITVPIIPGLK
PISTRKQLNQIPHRFKVDLPDELIMEVVRAKDNEAVRQVGVEWCIAQSKELIAAGIPVLH
YYSMGKSDNIKAVAKAVF
>A0A8I2W3W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSIADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>H1GEA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria innocua ATCC 33091|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDKAYLAVYPNASLPEVQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLESTKPVLEKEVRPIL
ELVPEEVEDEESGERLLDKVKERLTILVELDPPRTFDTSKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGRANEEGMTIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYVQNKQQLQIASK
>A0A3P5VM88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis spirochete endosymbiont|TrEMBL
MRQLSYSLEVFPTRTPAATRKFWHSITVFKQLQPAFYSVTANPANQINGSIKAIANRIKK
ITGAEVAAHMVLSDHNPETLDRIAQDYWDAGIKHIVALRGDETSVYAGKKRYAKELVEIL
LRIAPFNISVAGYPEKHPQCKSLNTDIDNLKDKIDAGAKRVITQFFFDPDVFLRFRDMAC
ERGINVQIVPGLLPIVNFSKLTKFAEKCGTNVPDFLLEMFNDGDELDHKLLAMNVLSHQI
TKLLLHGVKHIHFYTLNETVLTSQVCRWLEIAF
>A0A7R7DP46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinocatenispora thailandica|TrEMBL
MAAPTFSFEFFPPKTERGNELLWQAIRELEPLHPSFVSVTYGAGGSTRGRTVEITERIAT
ETTLTPMAHLTVVNHSVAELRNLVGRLAEAGVRNLLALRGDPPGDPMGEWVRHPEGVDYA
ADLVRLIREAGDFCVGVAAFPYRHPRSPDVASDTRHFIRKCRAGADFAITQMFFDADDYF
RLRDRVAAAGCDVPILAGIMPVTRMSTVERSEQMSGAPFPAALAAEFERVADDPEAVRQL
GVEQASRLCERLLAGGAPGIHFYTLNRSTATREVWHNLALPTAAAAGG
>A0A601HT78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar 4,12:i:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3C1HWJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MTIKEILDNKKTIVSFEIFPPKQQVNFDNVVNAAKELSALKPDFMSVTCGAGGGKRTNNV
EIAQKLISFGTPALAHLTCVRNTPESVRETVRDMKGCGIENVLALRGDMPRDLEEGETAL
VPELCHANQLVTILKEEGFCVGGACYPEGHPESANRDEDVDNLKYKVDAGVDFLTTQMFF
DNNMLYSYLYRLQSRGIRVPVFAGIMPITNSNQVARMVKLSSAYIPSKLLSFCDKFEHYP
EAMWQAGIDYATDQIIDLVSNGVRGIHIYTMNKPEVAIAIMKNIDKIIEAGNSI
>A0A4R0GKV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora zingiberis|TrEMBL
MALGLPSVLPNPQPAIGELVRDCQPTFSFEFMPPKTEQGERQLWQAIRELEPLQPSFVSI
TYGAGGSTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRHVIGRLAGAGVRNVLAVR
GDPPGDPTGEWIRHPEGVDYAEDLVRLVRRSGDFSVGVAAFPYRHPRSPDVATDTEYFVR
KCRAGAAFAITQMFFDADEYLRLRDRVAAAGCDTPILAGVMPVTRIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQTSEMCQRLLDEGVPGIHFITFNRSTATREIWQNLR
VGART
>A0A5P2U2J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyveromyces lactis|TrEMBL
MRISQKLQRAHEEREDATFSFEFFVPKTSQGVQNLYERMDRMYQTQPEFIDITWNAGGRL
SMLSTDLVATSQGVLGLETCMHLTCTNMPVSQIDDALKKAYDAGCENILALRGDPPINSL
GEEEEWKPCENGFRYAKDLVAYIREQYGDHFDIGVAAYPEGHPECDCDDKLLLHLKEKVD
CGADFMVTQMFYDVDKFLDWCARVRKAGITIPIIPGIMPITSYPSFIRRTQWCQINVPDN
FLELLEPVKDDDQLVRDVGTELMVELCQKLLDSGYINHLHMYTMNLEKASLMILEKLGLL
KRSNVGKDVIEPLEPLPWRKSLNPKRRNELVRPIFWQKRPYSYVARTSLWNEDEFPNGRF
GDSSSPAYGDLDLCGHSLIRQSVKKSIELWSTPQTLDDMSNLVTSYLEGKLKCLPWSDVP
LNHEVDDILKHLIDLNKHYIFTINSQPKVNGKPSTDPVVGWGPTKGYVYQKEYLEFLLPR
EKLPLFQEICQEHSDHLTYFAIDSQDNLATNHPEDSRANAVTWGVFPGSEILQPTIVEKA
SFLAWKEEFFTILKEWKLTFVEHKATESVNLVNHIIDNYVLINVVDNDFISTNDTIYDLL
QQLY
>A0A5P2U8B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyveromyces lactis|TrEMBL
MVTVKQRFDELKGPCVSLEFFPPKTEPGKRNLLARMERMCALNPLFITVTWAAGGTTAGK
TLELATIAQRELNVPVCMHLTCTNMNKDIIDEALKAARDADIRNILALRGDPAIGEEWSP
DADTEFKYAVDLVRYIKKNYGDDFCVGVAAYPEGHCEGEADESLQDPMRDLPYLKEKVDA
GADFIITQLFYDVDKFLSFEKSVREKVSSDIPMFPGLMPINSYLLFNRAAKLSHASIPKS
ILDRFPASVQSDDNRVKEIGVEILIEIIEQIHEKTNGRIKAFHFYTLNLERAIAQIVAKS
PTLSKILEEEDEVDDEWDSDVVLQDVDSLTLDEDNIKKRKRQSSASTDFPLNTSIINKLN
GMSHGNRVPSVPSRKVMISISQGTGVLGRNVTWDEFPNGRFGDSRSPAYGEIDGYGPSLK
VCNSTAYELWDHPVSLEDIKNIFIRYLEGSMKALPWSDLGLSAETAFIQEELIELNQRGY
LSLASQPATNGSQSTDNIFGWGPANGLIYQKAFVEIFVRKEEWNQVLKPKIESKNGEFSY
YLGDYTGYFETNLQPNSSNAVTWGVFPNSEVVQTTIVEEESFKAWRDEAFSIWIEWSKLF
PKNTPENTFLRKMHRDYYLVSIVHHDFINPDGLWDLLLS
>H3GAC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora ramorum|TrEMBL
MKIIDKINASVERQECFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMAEADIKKALDQAKDAGIQNVLALRGDPVRGASS
FDECDRGFSHAVDLVRFMRETYGDHFCIGVAGYPEGHTESQDKKLDIQYLKEKVDAGADF
IITQLFYDVKVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTSFCNTFVPEDVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRSAESVRPIYWSNRPKSYVNRTAMWDEYPNGRWGNSESPAFGELTESH
FAPTNTSTPSERRAKWGEAPASKEDIRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGALSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
PSVQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYADGSQSAKLLHEVHDTYFLVSIVDNDFVNGNIWDLFEASVSPVNSP
>A0A653HU81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxellaceae bacterium 17A|TrEMBL
MVVFFIILDTFMTTTTTPFSFEFFPTKTDDGQTKLLATFDELNALKPQYFSVTYGAGGST
RERTLGIVKALSEKSDTPITPHLSCIGDDKAKIGELLDYYKSLGINRLVALRGDLPSGMV
GLGELPFAVDLVKYIREHSGDYFRIKVAAYPEMHPQAKSFDADIQNLLNKYHAGATEAIT
QFFYNADSYLYLRDALAKKGVTQDEFPIIAGIMPITNASNLIRFADGCGADIPRFIRKQL
ADYGDDKKAIRQFGFEVMVNLCERLIAEGVPSMHFYSMNQVSPNKQLIEALGLV
>A0A1F3XDV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionales bacterium RIFOXYD1_FULL_44_7|TrEMBL
MPVDFCIGAACYPEKHSLAQSLQADINALKEKVEQGVDYLVTQMFFDVDMYSRFVEKTAA
VGIAVPIVPALFPFTSYKYVTSLPSFFGCSIPAELASRAEQYKKKSEEMRKLGIEWCVQQ
CEALRKCGAPSLHFYLHRNAPVAEVIKLIR
>A0A1B3PY55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium avidum|TrEMBL
MQTQKPTIADLLAAGDRPLHSFEFMPPRSEDDVYRLWSATDALVPMAPDFISVTYGANGS
RRDRTLRCTQHMVSTGLRTVGHLTCVVQSVSDLEQMVADYAESGVNHILAVRGDMPGGAG
QPWVAHPEGLPNATELVRLVKRVHPEACVGVGAFPDGHPESADIDLDARILVDKAEAGAS
FAITQLFFLPSHYQRLVNRVRAMGCDIPIIPGIMPITSYGQIRRFAELSGTDVPAELVAR
IEAVKEDKAAVRRIGLEAAVDMCCELLDSGAPGLHYYTLNRSRATTELRTMLARRRPQLA
GLPADFEATPAA
>A0A0L8BM77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer adhaerens|TrEMBL
MTAQTLYPAERGNLRLSFEYFPPKTDEMEAQLFQTAEDLSVFCPAFVTVTYGAGGSTKAR
SLTTVKRMVEEKGFANTAAHLTCVGAPKAEVDTVIDEFLTFGVRHFVALRGDPQGGIGST
YQPFPGGYESSSDLVRALRDHGDVEISVSSYPEKHPESPDVAADIDMLKRKVDAGATRAL
TQFFFDNDDFERYLERVRRAGIEIPIVPGILPINNLGQVQKFAGLCGASVPEVIVTRLSH
LEDQPAERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFERADEVSRG
EDVSLKAVAGAAA
>A0A7C5PG30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon|TrEMBL
MDFKRKIETGKFVVTTEVAPPRGTDTTLLIEEADLLSGCVDALNVSDNQRSIMRMSPLGV
AHVLQEQGHEVILHTTCRDRNRLALQSDLLGAWNLGVRNILAMTGDHPLLGDTMGTKPVY
DLDSTQLLQAIQNLNRGHDIMNRRLDGGTGFMAGAVVRPDPNDKMQLLRLKRKVSCGARF
IQTQPVYNTEEFKEFIEKVSHLNTHIIAGILPIFSLKTVKFINDKLPGIIIPQEVVERIK
NSTDPAEEGIELAAETIKKLQDVAGGVHIMPIITHQHTEAILKRAGMLH
>A0A7X3GY19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas zhuhanensis|TrEMBL
MSFNDGADDCNPVSRKPGYSSAGRLERVLRTGHFAVTAELAPPDSANPEEVYARARVFDG
YVDGMNATDGSGANCHMSSVAMCALLSRVGYETVMQISCRDKNRLAIQGDVLGGAALGIN
NILCLTGDGVQVGDHPEAKPVFDLDSISLLETVARLRDKNEFCSGRKISDPPRVFLGAAE
NPFVPPYDFRPHRLAKKIAAGAQFIQTQYCFDLPRFRTFMDRSRDLGLLEKCFILPGVGP
LASARTAVWMRNNVPGIHIPDAVIKRLEGAKDQKKEGQKICIELIQQLREIEGVSGVHVM
AHRQEDTVAEIIEKSGVLDERQLWSPSSDEVLRRNRA
>F5HGC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)|TrEMBL
MKITEKLQKAEKEGRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALREAKSHGCQNILALRGDPVAGTST
WEPTPGGFMNAVDLVRYIHEHYPGDFCVAVAGFPQGHPETPDTPEGRAQEMEWLKAKVDA
GAEFIFTQMFYDTSIFFDWVKRVREAGINVPIIPGIMPIQNWEKFEKWVQRENIIVPSHF
YEALNPVRGDDEKVRQVGTKLVADMCKTILDNKEAGIKGLHIYTLNLEKGARMLLRELGF
EGRREQIAPLPWRPSLTPSRREETIRPIFWANRTRSYLSRTADWDEFPNGRWGDSRSPAY
GDLDGYPVSIGITAPDAYNLWGHPTTSSDLHALFARFCRGDLAKLPWSTQPPASETSLII
EQLAKMNELGYLTINSQPAVDGVRSDDKVHGWGPPGGYVYQKAYLEFFVSPDLLSPLIRR
IEKDPRITYYAVNKQGDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWAHLYPAESPSRKLITDTMNTSYLVNIVANDFRDGMSIFEPFLLDQTTVRKVVEGV
KGTVEGIVEGVKGVVGA
>D4C7Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. M62/1|TrEMBL
MKIRDILAQGKPTLSFEVFPPKAEDKYDSVEEAAIRIARLKPAFMSVTYGAGGGTSKYTV
DIASSIKNQGVNALAHLTCVSSTKEEVRRVLGELKTRGIENVLALRGDIPEGGPLAHDYR
YASELIREIRSFDGDFCIGAACYPEGHVESANKTEDIEHLREKVEAGCDFVTTQMFFDNN
ILYNYLYRIRERGITVPVVAGIMPVTNARQIDRICRMSGTYLPARFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAEQIKNSLSEILQD
>A0A3S0U025|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria sp. HSID17590|TrEMBL
MADPPTGTSWLVRRPRRSTLVSFEVFPPRPDADPDTVWSRIDAMAQAGPDFFSVTHGHSA
GTGVSREALRHLRRTTSTPVMAHFTCGGTDRAGLERSVEQLLDDGVRDLLALRGDPPLGA
GEWETPAGGLGRASELVSLIRDVERRRFGDGYRPGTRPLSVSVACYPSPARGRDFEADLA
SLWEKQEAGADYAITQVLYEPEDYARFLERARSEGIHIPVVAGLMPLTNPQRLRRMTEIT
GVAVPRRLTDFLAAGTPDELRRRGIAATLSLIDDLLDLGCAGFHLYTFNRPDAALTILEH
LRVRDAAREYRGRSPAA
>A0A522X7H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionella sp|TrEMBL
MNKPLFSFEFFPPQTAEGIEKLAATRKQLAALDPEFFSVTFGAGGSTRDRTLETVQQIKA
EGYSAAPHLSCVGSTRENIRAILETYRHLGINRIVALRGDLPSGMAGIGEFQYANELVSF
IRAQTGEHFHIEVAAYPEFHPQAKSPRDDLLNFKRKAAAGADSAITQYFYNADSYFYFVD
QCRKLGVTIPIVPGIMPIVKFSQLARFSDACGAEIPRWIRRTMESYGDDTESVQAFGQDV
VAALCERLLAGGAPGLHFYTLNQAAPTLAIWKRLGL
>A0A1E9B9K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC056C01|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQDLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFHYATD
LIEFIKEQSPHFEIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAQYIHQATHALFNHQSLG
>A0A436M007|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.001.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A0C3DRZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scleroderma citrinum Foug A|TrEMBL
MRISKKIEQSQKEGKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
ELTSEMVRLCQGVLGIETCMHLTCTNMPEEKVDIALREAKKHDCRNILALRGDPPQGKDE
WEAVEGGFVHGIDLVQHIHKHYDDYFDIAVAGFPQNMLLPPEERDLEIQYLKEKIETGVD
FIFTQMFYEVDVFIEWAKAIRAAGITIPIVPGIAPIQTWNGFLKATSLAKTKIPQSFMDA
LEPHKNDDEKVRAIGTKLVADMCRKILDADLGIRGLHFYTMNLEKGTKMLLQELNLVPRV
ETVKPLPWRQSLTPNRRQENIRPIFWANRAQSYLSRTENWDEFPNGRFGDSRSPAYGELD
GYGVSLKQTKEEALKLWGEPKTFSDISTLFTQFCRKKLSALPWSDQPVSGETSAIAPELA
KMNKHGFLTINSQPAVNGARSDDPVFGWGPSNGFVYQKAYLEFFVNGELLEFLLSEIETD
GFMTYYVINKQGDLRTNSHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGVK
WANVHEAGSASRQLIMDVMNNSYLVNVVHNDFKDAKAIFVPFFKAGEKYAASRANGGLHV
NGNLN
>A0A0X8LPV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio fluvialis|TrEMBL
MGYTHASHIDALNQNIADLSDINVSFEFFPPSTPQMEETLWNSVHRLKTLKPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDASREELIQIADDYWNNGIQNIVALRGDI
PPGGGKPDMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRAI
TQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFDG
LDDDPVTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPSL
>R9CED1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sartagoforme AAU1|TrEMBL
MNIKNLFNEKEVVFSFEIFPPKQESKIDIIYNTLEELKDLKPDFISVTYGAGGSLSKNMT
CEISSVVKKKYGIEALAHLTCINSTKTQVDYILNNLKESGIENILALRGDIPSNYDGISE
FNYASDLISHIKKRNDFNIVGACYPEGHLNTVDLDTEFKILKKKQDSGATHLISQLFFDN
EYFYNFLDKTNEYNIDIPIQAGIMPVINTKQIKRIVSLCGAKLPKKFIKIMNKYEYNPEA
LRDAGIAYAIEQIIDLISSGVDGVHLYTMNNAYVAKRISTNIFSILDTINNCEKVIN
>A0A521F9E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobius litoralis|TrEMBL
MTAPAISFEFFPPQNLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRDLTRDAVATIHK
HSGLNVAAHLTCVNATKAETLAIADQFAEAGVNEIVALRGDPPKGSGAFQPHPEGFANSV
ELIEALAATGKFKIRVGAYPEKHPEAGSHAADVEYLKRKFDAGADEALTQFFFEADTFFR
FRDACAKAGIDKPIIPGILPIENWKGARNFARRCGTDVPAWLDDAFEKAERDGRQDLLAT
ALCSELCSDLIDGGVDSLHFYTLNRPELTRDVCHALGVTPKVNLENVA
>A0A2H6IU88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Bbin10|TrEMBL
MLDTSNNRTPNGNSNELNVSFEFFPPRTRKMEETLWQAIRRLEPLGPRFISVTYGAGGST
RERTHATVARILKETALKPAAHLTCIGATREEVDAVIRDYWDLGVRHIVALRGDPADGEG
TPYTPHPGGYANAAELTAGIRRIADFEVSVSAYPEKHPDSPDFAADIDMLKAKVDAGATR
AITQFFFDNDLYFRYLDRVRAAGIDIPITPGFIPILNFRQVAKFAALCGTHMPSRIAARY
EGLDDDPETRKLVAATIAAEQASDLAAQGVTDFHFYTLNRADLVFAICHLLGLRPKAPAE
KENEASQ
>H2CLP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptonema illini DSM 21528|TrEMBL
MHRISDRLKKKQPVFSFEFFPPKNDDGERLLMQTIEDLKALEPDFVSVTYGAGGSTRAKT
REWVRSIQDRYAIPAMAHLTCVGSGREEIRSILEDLYSDGIRNIMALRGDPPKGETAFVA
PADGFRYANELISFIRSTGLDFCLGAAAYPEVHGEAPSAAEDLRNLKRKVDAGADFLVTQ
LFFDNEKYFSFVDQVRAAGIEVPVVPGIMPITAFKQIERFTAMAGCAIPDSLVKSLAGVQ
DDAEALLNLSLEFTLRQCEELLSKGAPGIHFYTLNQSRATAIILDRLRRSVSAERR
>A0A1I6HN96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter daqiaonensis|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQVVRDRLAEVNPDFFSVTFGAGGSTRDRTIETV
LSLHGQGISTAPHLSCVGGTREKIAELLDIYKESGVSRIVALRGDMPSGMGAAGELRYAN
ELVAFIREYSGDAFNLEVAAYPEFHPQARNAEEDLKNFARKVEAGANSAITQYFFNADSY
FYYIDRLEKMGITIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTDMCERLLAAGAPGLHFYTLNQAEASLNIWNNLGLANRDKISF
>A0A1Q5PKD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boudabousia liubingyangii|TrEMBL
MPVSFELFPPRQPALDSPIWAGVERLIQANPAYVSVTFGANGKSQDASLEALSRLRTYQV
PTLAHLTCVERSRTQLADLIKRIFDLGVRDILALRGDPPKGQSRWQAPEGGLNYASELVH
LIRETAASHLDNDESVDIGVAAYPAGGIQSRLDALSALAQKEAAGADYAITQVFFDARDY
QSLLEATVVNGISLPIVPGIIPFTDLPRLQRLQQLTGVPVPARLQELLSEPDARLRFRQG
VKETMTFIDQVVAAGAPGLHLYTFNRTRPALDILKFLRLAGSIPRDPQTAEQQVELLAEA
AHRITLTH
>A0A7X9HUP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MLKHILDLLKDSPYLLADGAMGTYFSEITGSSTDRCELANIDTPDIIKRIHEEYIAAGSQ
LLRTNTFAANTWFLKKDIDTVKEVVRKGFEIASLAAKSARNKGRDVYVLADIGPIPEIEG
YDVLAEYKAIVDAFFECDASNFIFETFSSYETLLEVCKYIKSRNKNAYILAQFAVSPDGY
TREGISGERIISSVRNSKLVDSCGFNCRSGPIHLLEYIKRTGILSIKNDNKSEFTISIMP
NAGYPTIENERTIFLNNPQYFAQIMCDIRNTGVKILGGCCGTTPRHISETCIALDNSSKN
IGSYSSPVLKKGQNRTSKKNSFRERLDTGKKVIAVELDPPLNANVSSIIEGAKVLKEYGA
DIITIADSPLARARVDSSILAAKIKREAGIETLPHITCRDRNLNAIKALLLGLHIEDIRN
VLAVTGDPIPEAERSDVKGVFNLNSFMLAEFIYELNQSEFLDDEMFI
>A0A6G3LVI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoflavonifractor sp. 60|TrEMBL
MKLCELFKQGRTVFSCEVFPPKKTAPVDSIYKTLGGLKDIRPDFISVTFGAGGSQANQST
REIASLIENQYHIPAMAHLTCVVAGREDADRLLTELKEEGVENVLALRGDINPDYPPKTD
FKYASELVAYIRERGDFGVSAACYPEGHPESPDLVSDIRHLKEKVDAGAQHLVSQLFFDN
DDFFRFLERARIAGINVPIEAGIMPVLSKSSIQRMVSGCGASMPSKLTRILARYGDHPEA
LREAGIAYAIDQISDLIAGGVDGIHLYTMNNPDVARQIAGSISSIRTV
>A0A7X8M1E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MRISELYKNKQRKTLALEIFPPKPDVPLDTLFSSIEGFKELSPDYISVTYGAGGSQRGRT
VEIASKLKNHYGIEPMCHLTCVGHSVEEIDELLAKIKEENITNILALRGDPPVDQPDFSY
ENGAFKYANELIAHIKKTDDFCIAAAAYLEGHSDSKRLSEDRRYLKQKVDAGVDLLITQL
FFDIRLYFDFLDRCEQLDINCPVIPGIMPIFSARIKTMTARSGCSIPANLVLMIDKYQDS
PEDLKKAGEEYAAYMIRELLDGGAPGIHLYTMNKLESTKEILKQAGLR
>A0A7K0JUZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrimicrobium australe|TrEMBL
MLAEGRTYSFEFFPPKTDEGRRHLARALVELQPLEPSFVSVTYRGGPSSREPTHDLVAGM
LKTTTLNPMAHVTCVGHTRLELADILVQLRKAGIDNLMALGGDPPAPGVPQGELRYAQEL
VELARAIGGFSIGVAAHPSVHPRAASREADRAHLAAKLRLADFAVTQSVFSVREYVSLVE
DLAALGVDKPVLPGIMPITALSSIDRQRELGAVVPDDVEARLRAARREADVRAVGIELAT
ELCAALLDAGAPGLHFITLNRSSATREIYGNLGIVASAA
>A0A7C6QU54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MNIKQRPFIFDGAMGTYYASISHNPLARCELANIYDRNTIVNIHKQYIDAGCNAIRTNTF
GANRISLESGYDTLKEVIVKGYEIAMEAVKGTDVLVFADIGPIPSSETEDLWEAYEEIVD
LFLELGAKYFIFETFSSDEYLYDLSRYIKTKNSQAFILTEFAISPEGFTRLGKSGRALIE
KALGNTYIDGCGFNCFSGPSHLLKFVKNLHIENIENRIISIMPNSGYPTIINNRTFFENS
KEYFAEKVLEIAKQGIAILGGCCGTTPDYIRETVAKLKGLSSVEIIPYKKEQETTVRKAV
VTNILLEKIKNGRKIIAVELDPPVDTNIDRFMDNAKILKELGIDAITIADCPIARARVDS
SLLACKLKRELDITPIPHLTCRDRNINATKALLLGLNIEGINNVLVVTGDPIPLAQRDEI
KAMFSFNSAILANYITTLNNTVFSHPFNICAALNVNARNFNSQLAHAKNKMENGVNMFLT
QPILTEQAFENLKIARERLGAKILGGIIPIVSYKNACFMNNEISGINISEEIIDSYKGVT
KEEAGKLAVKISCEIAKKIYPYVDGYYVITPFNRIDIVSEIIKYIRGITCTKIEDYQCNL
SG
>A0A4R5FTP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea mesophila|TrEMBL
MSGLRAAFEAGRFAVTAEIGPPGGADAEAVTRKAELLRGWVDAANVTDNQGANVRMSSLA
GSLLAQRAGVEPVMQLTCRDRNRIALQSDLLAAGALSIPNVLLLTGDHPRFGDHPEAKPV
FDLDGVQLVWTARTLRDDGVLLSGKAVPARPAWLIGTVENPFAPPPRFRARRLAKKVSAG
AEFVQTQYVFDFEVFERWMADLRDLGVTDHCKVIAGVGPIRSLRALDYMRTAVPGVHVPD
EVDRRLRGVPAGRVAEEGIRMCAEAVQRLATIPGVAGVHIMALGFEHGVPDILRRAGIPR
PPAALPDHHRHHPMEGIGHAR
>A0A0Q9JIT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces sp. Soil535|TrEMBL
MSPAMLLEEFSLEMTGKDVPGLEEAADLIPPSTRINVTFLGNENLETRLATSRAVHERGF
TPVPHISARRLASRGQLEEFLGALRDQGTSSEVFVVGGDPHTPEGPYEDSLQVIQTGLLQ
AYGVHQVGIGGYPEGHPDISDAQLWSALTGKAAALREQGLEGTIITQFGFDLAPVFSWIE
RVRDLGIDLPIRIGVPGPAGIKRLLTFAARFGISSSAGIAKKYGFSLTNLLGTAGPDKFI
TQLTDGYDADRYGDLKLHFYTFGGLRATSEWITSFSEDQK
>A0A1Y0MAV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. SA4-10|TrEMBL
MKITDHIKKAAGKTLFSFEIIPPKKGNNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYIN
KADGLLDRKITRMRPGTLGICAAIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMSHQKYFTANDGGNHYAADLVSQINDLNSGKYLHDVIESTTKPDFCIGVAGY
PEKHLESPSLQTDLRRLKEKVDAGADYVVTQMFFDNQKYFEFVEAAKKAGINVPIIPGIK
PIAVKRHLQLLPQVFRIDLPETLISNVERCKTNKDVRQVGIEWAIQQSKELLAAGVPVLH
YYSMGKSDNIQAIASELF
>A0A2H6EKU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Abin04|TrEMBL
MKIIEHLNKASETLISFEIIPPKRGGNFKQLMAALDDLVKFNPPFIDITSHAAEVIYEET
SEGDYKMKVKRKRPGTLGICALIQNKYNVDAVPHVICKGFTKEETEDFIIELHYLGIDNV
LAVRGDDSGFEKPIKYNRSANIYAVDLVKQITDLNKGKYLEDTLLDADRMSFCIGVGGYP
EKHFESPNVLMDIKYTKEKIKAGADYIVTQMFYDNQKYYDYVKLCRDNGIDVPIIPGLKI
LTSKNQLVSLPKSFYIDIPNELAEEVENAKREHIPEIGAEWTLKQVQDLLEHNVPAIHFY
VMQNTKPINLVMNKLKL
>A0A1J0PA02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. SynAce01|TrEMBL
MLLQQALADGRFAITAEVMPPRGGDPGRTLRVAAGLKGLVHAVNVTDGSRAVMRMSSLAL
CRLLLDIGLEPVLQLSCRDRNRIALQAELLGAHALGIRNLLCLTGDPVGAGDQPGARPVN
ELEAVRLLQLVRGFNAGEDPVKGLLNDGPTSLFAGAAADPQSPSWSGLKTRVGRKKAAGA
RFLQTQMVMQPEALKRFCGEIAAPLGLPVLAGVFLLKSARNAAFVNRMVPGALIPQALID
RLAAAEDPAAEGINIAAEQVATYQSIAQGVHLMAVKAEERIPMILAKAGVAPVEPLSLRL
RPG
>A0A1H1LND0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium siliguriense|TrEMBL
MSQSTLRRLLSTARYEVLPTAGIVERIEEYVAPGREITVTASTGLTLEATLSTAEQLQAL
GFRAVPHLAARMIHGRPELTEVVDRLAEAAVDRIFVPAGDATPPAGGYVGAHDLLVDLSS
MAAPFRHIGVSAYPESHPIIPDDVTVQAMWDKRDYATHLVSNLCFDPALIASWVGRVRSR
GIELPLVLGIAGKVELGKLARVATKIGVGESTRFLRKNTATFTRMAKPGGYNPRKFLDKI
GPVLDDPDMGVAGLHVYTFNQIKDTEVWRRKQLAALGGAEEVSTAW
>A0A353QYQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium UBA9971|TrEMBL
MNFIYDVLINTKEKKMKLKEIYNSNKPIISFEIFPPKAQNTDELNHKINDLFEELRILSE
FNPAFISVTYGAGGSTRETTLDIVTKIKNNMNIQPMPHFTCVGSSKDDILEYLKKIESAG
IKNILALRGDPPKGETKFVKPEDGFGYANELVEFIKSNTDLGIAVAAYPECHPECCSLDK
DIENLKRKIDYGADVAITQLFYDNSCYFEFIEKAQKQGINIPIIPGILPITSYSQIERIS
TLSGCKLPAELSRKLAENKDDNEAIKQIGVEFAVKQANELLKSGVSGIHFYPLNKAFAVK
TVLENLKIQEKV
>A0A2S3ZR46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium zongtaii|TrEMBL
MTATPTTPPADPDCRSSIPFSFELYPPKTDAATTALHTTIDALAAARPRFISVTYGASGS
SRTSSLDVLRYIRRATTVDPMAHLTCVGSSHAEASSLIREFLDAGVSSFLALRGDPPEGL
TENDAFLGDLHSAGELVQLIHRVQAERVPYQETPIPGLPRARAVKTEREHVRIAVAAFPN
GHPRSRSTAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPV
TSPGRLRRILELSGEELPAELSIQLEVEPTLEGQREIGISHAAALAQKLIAGGAPGLHLY
AFNQHETVLAVLDRAGALAPAQPVVSAHTPPPTHPSTSPADTRAGIHSTKDHY
>A0A6G7H3V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus wulumuqiensis R12|TrEMBL
MTRISLELVPRSRSKLRAELALVAEQFPGVDTVNIPDLTRFSTRSWEGCAFAPAGLRAIP
HVRAIDLNPKEPLPMVGAFLAHGIEEVLIVSGDAPSDMNRRVYNVDAEQAIRRFRRELPH
VKVYAGLDPYRQSFAAERDYLERKLEAGASGFFTQPFFDMRLVEAYADIVPDGAEVWWGA
TTVTEEGSLNYWQTRNRAVFPRAFELTMDWDRRFAAQLLAFARAQGQHAYFMPVKTDVGA
YLQGIV
>A0A2D3W0R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurospirillum sp. UBA12182|TrEMBL
MLTDKIRSCKSGILLYGMTPPKTEHSEEELQVIAAKHIQRLDKLEIDGLILYDIQDESDR
TKEQRPFPFMQTLDPCEYALNYLDAPLRYPVIVYKAVGKYAKEDLQQWLKNRQGKDFHTV
FVGAASKSTTVHITIPEAYEMKKEFAPDITLGGIAIPERHMKKHDEHLRVFSKIQSGCEF
FVTQCVYDLMAAKKFLDDYALYAKEHQKKMVPIIFTITPCGSAKTLEFMKWLGISIPSYL
EERLKNSEDILHDSLKLSRDIFEILYFYGKGKGIPIGCNVESVAIRKAEIDASIELLNEV
KKIMEEA
>A0A811GLU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter mucicolens|TrEMBL
MSESISPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLRDILQAYKREGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVTKVKAGADAAITQYFFNADAYF
DFVDRARAKGVNVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHSEAPLAIWKELTV
>A0A452G4N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capra hircus|TrEMBL
MVNEPRGNGGPGPRWEGSSSGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKH
IRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQDERETEAL
>A0A4Q0IIK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Isolate-007|TrEMBL
MKVTDIIAARQTPGFSFEVLPPLKGRGINQLFKNIDILCEFDPLYINITTHRSEIVFKDT
SDGLYRRVSERSRPGTVAVAAAIQQKYGIPAVPHMICSGFSKIETEYALIDLNFLGITNL
LLLRGDKAKHESRFTPNADGHAHASELQQQVNDFNRGYFIDGTKMDIITGETFSYGVAGY
PEKHEESPNPDIDLQYLKLKVDNGADYIVTQMFFDNEKYFRFVERCRNAGINVSIIPGLK
PITTMSQLNLLPKVFHVDMPSDLANELMKCTSDAQAKEIGVEWCTMQARELIAHNVPSIH
FYSLNATRSVERVARTVY
>A0A191UHV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter wuianus|TrEMBL
MELSVEFFPPKTPEGENKLHLVRERFSETLKPSFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRDSVREMLKQYQAIGVKRIVALRGDLPSGMGQYGEFHHANELVAFIR
SETGNWFHIDVAAYPETHPQAKSPASDIDFFAQKMKAGANSAVTQYFYNSDAYFRFVDEA
YDLGVTQPIIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDIDSIRAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLDLTK
>A0A2G0WGS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ICMP 561|TrEMBL
MSQDRSFSFEFFPTKTEAGHEKLLNVARQIASYNPAFFSCTYGAGGSTRDGTINTVMQLQ
NEVKVPSAPHLSCVGDSKDDLRVLLNQYKEAGIKRIVALRGDLPSGMGMSSGELRYASDL
VSFIREETGSHFHIEVAAYPEMHPQARNFDDDVKNFVHKAQAGADSAITQYFFNADSYFH
FLERVQKKGVTLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A3E1J1W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis|TrEMBL
MAYKPKFSLEVFPPKRTSPIGTIYDTLDGLQGLDPDFISVTYGTGKLQDRTATARIANTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VSYIRSKRPDLPILGACYPEKHPEAESLQADIENLKRKVDAGVTYLISQLFYDNEDFLRF
RDLARAAGITVPIEAGVMPVANASQVKRMTSLCSSRITSQVSAMMDRWGSNAECLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWSNVKPLFTKIG
>A0A1C3X9P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium miluonense|TrEMBL
MAQIDENPLGVGLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
SGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQGDVLGAAAMG
VCNILCLTGDGVQVGDQPGAKPVFDLDSMSLLETVRTMRDEAKFLSGRKLTSPPKVFLGA
AINPFAPPHDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLAEKCFILVGV
GPLASARTARWMRSNVPGVHIPDEIIRRIEGAADQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEIVHESGVLRGRQPWKHEASRSDVLVAERLGHIREGQEERQQEMVEAAA
HHPQHKAD
>A0A257XFV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 12-66-7|TrEMBL
MQFDAERREDPRHEVAPAARSDAKALAMLVERLSIEVSPKEVLHSGHALGVPAGTRTFIT
RLPRGSLEDTRAAAVALRQAGLQPVPHVAVRTVPDAGTLERWLRFFVRDAGVEEILLIAG
SQERPLGAFGETADTLASGVIEGSGLRAVSFAGHPEGHPVADADELQRAIDVKNEFAART
GLSCALVTQFFFDATPVIAWERRLRERGNRLPIDPGLHGVTGVPSLLKHALACGIGASVK
ALSAHGSGGILQFAQIRTPDALAQALAAALANDPDSLFRGFHLFPLGGL
>A0A7Z3GPM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas multiresinivorans|TrEMBL
MSQKDRRFSFEFFPAKTEAGHEKLLATARQLAAKKPDFFSCTYGAGGSTRDRTLTTVLQL
DGDVQVPTAPHLSCVGDTKAELSALLAHYKDAGIRRIVALRGDLPSGMGMASGELRFANE
LVEFIRAETGDHFHIEVAAYPEVHPQARNFEDDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAEKLGVSIPVVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDIASIQAF
GEQVITDMCERLLEGGAPGLHFYTLNQAEPSLALWNNLKLPR
>A0A2U2SRK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ardenticatenia bacterium|TrEMBL
MYAKLLRGIAMWQRLATSFQRIRAVEAWRQARLCLERMLANQIDRALFKCQSCGQCLLFQ
TAFICPLTCTRELRNGPCRGSNPHHCFIKPTRACTWHLIYARAERQGAMERLLEVNAPRA
APVNRSKASVDTPHAQRCQHGYGPRLLDRLINPGRYYTEWEEYHNRQRALPWWRGDSRYH
PPEYSEPASQLEDRLRSGKFAISVEVAPPMEPTGVRIARLAEQLEGHVDTFNFTDNPRGV
ARMGGLACAIHSSANGIEPVLQIQTRYRDRYNLESEVVGAHLAGVHNILCMCDDTGRLGP
GPPPMPGPADLDTVQALWMLRRLRDEGVNVDGLQVEHRPRYFLGAVVSPCATLPRYAALI
TQKKINAGAQFLQTLPIFDLSRFCDWMEALDKRDLLGKAYLIVAVEPPKNANHLRFLASE
VPGVVVPSGLHARMAYSRDPYEEGIQIALEIIAGLKGLRWVHGLHIHAPGREEVALRLVR
ESGLRDFTPQVESESGNGRDKAGSDPVLQLATNGLPTRF
>A0A8H7Q774|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Umbelopsis vinacea|TrEMBL
MKIIDKISQPREDGKPYYSFEYFPPKTEVGVANLYDRLGRMAQTQPAFISCTWGAGGATA
ERTIGLCATAHSVYGIETLMHLTCTNMGKDKVDEALKQAKEAGIQNILALRGDPPRGQEY
WSPCDDGFCHAIDLVRYIRQQYGDYFCIGIAGYPEGHVDSQDKDQDIVYLKEKVEAGADF
IVTQLFYDVDTFVHWQKQCRDAGISVPIVPGVMPIQSHQAFRRIINLCNTKVPPHILEDL
NDIKADDQAVKDYGVKLATTIVSELYHKHHINCFHFSTLNLEKSVRLVLQDLDFLPKGVQ
SSTALLNGKSVKSTALLAEAHRAETWDEFPNGRYGDSRSPAFGDNTYGAGVALPTSKASA
KWGYPTSPNDITNLFIAYISGELQTLPWCDQALQTETDAIRKSLSTLNKAGLWTVSSQPS
VNGAPSDDPMFGWGPRGGYVYQKEFIEFFVTSDKLPALLRQLAKDPIITYYAANRAGDSK
TNVDDHDSQNAVTWGVFPGKEIVQPTIIEQVSFDAWRVEAFELWTEWEQQYPPESESRKL
LKHLGDDTWLFNVVHNDFQNPGKLFEVILG
>A0A254NVA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharibacillus sp. O23|TrEMBL
MGLLDELRTRVVVADGAMGTLLYLNGIDRCFEELNLTRPEQVRQIHQAYLGAGAEVIQTN
TYAANDHKLKRYNLEYELEAINRAGARLARSAAQGTGAYVLGTVGGIRSTKPGEVSLGEI
RRSNERQIDALLSEGVDGLLLETFYDPEELRTTLALARKKTELPIVAQVSTQDSGYLQDG
STLTEMFAILEDLGADVVGLNCRLGPFHMTRYLKQVPLPKHAYLSAYPNAGLPEYNEGRL
RYRSGADYFGRSALDLRDEGVRLIGGCCGTTPEHVAAMVEAVKGSAPITDKVLEALPGSL
SRTEGRIEVRETAEELAGAGVVPPTGKLFHELTAAKDHSVIVELDPPRTLRTEGFFKGVQ
ALKEAGIDALTMADNSLASPRIANESLAAVVKEKYGVKPLVHVACRDRNMIGLQSHLMGL
AASGINQMIAITGDPSKVGDVPGATSVYDYNSFDLIKLCKQFNEGRLPSGRSLGVRANFS
VGAAFDPNVRHLDKGVQRLEKKIAAGADYFMTQPVYDEKRIEELYHATKHIKQQIFIGIM
PLISAQNASFLHNEVPGIRLTDGVLERMQRYEHDKEAAMQEGMNIAKSLIDVVLEYFGGV
YIMTPFLRYEQSAELTRYVHEAAAKRGNQRARLVQ
>A0A3S2TT26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niallia taxi|TrEMBL
MNFRDELQKRILIGDGAMGTLLYSNGIDNCYEELNITHPDRIETIHSAYLEAGADILQSN
TYGANYYKLKRYGLEEEVSTINRKGIAIARKAANGKAFVFGTIGASRSFRKSDLDLDEIK
RCFREQLYSQLIENPDGLILETYYDLEELEMVLKIARNETDLPIIANVSLHETSYLQEGI
HLNEALLRLEALGADAVGVNCHLGPHHMIRSLEEVPLPKKAFLSVYPNASSLPEYVDGRF
VYEAVPDYFGYSAVNLRNQGARIIGGCCGTTPNHIAAVKKALGNIAPIKEKKIIKRKVEV
IEVAVKETKKGLYEKAKLERTILVELDPPKKLGIKEFMKGAKALHKAGVDSITLADNSLA
SPRISNVALGTILKKEIGSEPLMHITCRDRNMIGLQSHLMGLQTLGLNEVLVVTGDPSKI
GDFPGATSVYDLSSFDLISLVKQFNEGLSYSGKSLGKRTNFKIAAAFNPNIRHLHKAVER
MEKKIACGAQSFLTQPVFSTSQIEDVYEATKHLDTPIFMGIMPLTSTRNAEFIHNEVPGI
KLPDTVRKAMASAGNDPIKARAEGIAIAKELVDAAAERFKGIYLITPFLRFELTEELSKY
IREVDNKRVVELTANEQ
>A0A0T7GJK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neorhizobium galegae bv. officinalis|TrEMBL
MTADSETFSVSFEFFPPKSEEMEGQLWDTVDELALWDPRFVSVTYGAGGSTKAPTINTVR
RLVGETSLATAAHLTCVDATREETHSVVGEYRAAGIRHIVALRGDPASGVGTDYRPHPQG
YANAAELVRGLTELGGFDISVSAYPEKHPESADLGADIEMLKRKADAGAARALTQFFFDN
DVFERYLEKVRAAGIAIPIVPGIMPIQNLTQLKRFAGRCGSSVPSFLDARFEGLDDKPED
RASAAADIAAEQIEDLIRRGLGDFHIYTMNRAPLVSAVLQRLGRRQIRTPRIAAA
>A0A673U5B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Suricata suricatta|TrEMBL
MTVEVPLPKRPGRGHIGDGASGLQLGCFPPSRPASLCNLTPAPRPAPLRRRSPGGHAAAA
GASSLSHPPKGGRNSVMVNEPRGDGGPTPRLEGSSSGSESSKDSSRCSTPGLDPECHDRL
REKMRRRMESGDKWFSLEFFPPRTAQGAANLISRFDRMGAGGPLFIDVTWHPAGDPGSDK
ETSSMVIASTAVNYCGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQW
EEEDGGFSYAADLVRHIRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFI
ITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIE
PIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRR
PLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYL
FYLTSKSPREELLKMWGEELTSEESVFEVFACYLSGEPNQNGYKVTCLPWNDEPLAAETS
LMKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVGAL
LQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKD
EAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNR
PGTEQETETL
>A0A0E0UE31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium meliloti (strain BL225C)|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHERCYILVGVG
PMASAKTARWIRSNVPGIHIPDSIIKRLEGAQDQKKEGKQLCIDIMNEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLRGRKPWTREAAPTDALVAERLEHIREGKEENQQQMAEAAAH
HPH
>A0A2S7T1L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavipsychrobacter stenotrophus|TrEMBL
MKLTQHVAEAKKTIISFEVLPPTKGRSIDSLFSTLDPFMEFKPSFVNVTYHRAEQIYKKR
TDGSFERVEIRKRPGTVGICAALMNKYQIEAIPHLICGGFSMEETENALIDLHYLGIKNV
LALRGDAAANEKFFVPHPHGHNYAEELVKQIITLNKGQYMEDDILDGVKTDFCIGVAGYP
EKHFEAPNLDIDVANLKRKVDLGADYITTQMFFDNNHYYDYVARCNAAGINKTIIPGLKP
LSTKKQLTIIPRVFNVEIPVELYTEIMKCKTDADVELVGTEWLLNQCRDLLKNNVPVLHF
YTLSKPHIIYNVLKQLF
>A0A3D9BYS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosalinus sediminis|TrEMBL
MTDAPEVSFEFFPPKSLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRELTRDAVGTLH
KHTGLDVAAHLTCVNATREETLAIANGFADAGVNQIVALRGDPPKDSGGFTPHPDGFANS
AELVEALAETGRFTIRVGAYPDPHPDAPYEGADVDWLKRKIDAGADEAITQFFFETEAFY
RFRDRCEKAGIDAPIVPGIMPIENWAGVKRFAKACGAYIPAWLDDAFAKAERDGRADLLA
TSLCTEMCTELLENGVDKLHFYTLNKPELTRDVCAALGVKPEARLEHVA
>A0A2N2Q8T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-9|TrEMBL
MALPVSFEFFPPKTPEGAEKLRVVRQQLYAQKPEFCSVTYGAGGSTQQGTFDTVGAILAE
GVDAASHFSCIGATKASVREQLATLKAMGVKRLVALRGDLPSGYGIGGEFHYASDLVAFI
RAETGRDFHIEVAAYPEVHPQAKSPESDLQAFATKVRAGADSAITQYFYNSDAYFHFVDE
AHKLGVDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDIASIKAFGLDVV
TDLCDQLRNAGVPALHFYTMNQSVATLEIMKRLELG
>A0A0H1AJ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. KE1|TrEMBL
MRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSVTYGAGGSTRSGTVRA
TRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVRHP
EGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVDKCRAGADYAITQMFF
DPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVFPRKLEERMRASADDP
AAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLGLHDDKG
>A0A0Q8QY52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Root710|TrEMBL
MPRESRAGDIGDSSSPRALLADCSLEITARDAAALDEVRADLPSGTQVSITYLPGDSIEK
LIDAAARVRGAGFEPVPHISARRLSSLSELQRFLSGLASGAGIDRLFVIGGDPAQPAGPF
SSALDVIQSGFLEDFGIRKVGIAGYPEGHPQLTQEVLRRAMSDKLEALTRRDMDAEIVTQ
FVFDADHVLGWLTALRADGIDAQVRIGVPGPASIKSLLRFASRCGVSASTKVLAKYGISL
TRLLGTATPDILVEALAQGLSESAHGGVTTHLYPFGGVAQSASWLAGHLRDGARPEKLRP
R
>A0A504U7T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium glycinendophyticum|TrEMBL
MAQIDENPLGPHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKVF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDEQKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMKKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDHVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGILKGRKPWKREHARADDIAAERMREIGADPVQDQQEMAAKAA
HGEPH
>R2NTF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus malodoratus ATCC 43197|TrEMBL
MSSTISFEVFPPNTQIGAEKLFKTLKELKQLQPDFISVTCSNNRQTIEETTLKVADYIHK
ELNVPTIAHLPAAYLSQAQLVELVTQLDQIGINQILALRGDILPDLPPKKDFVYASDLID
YVKKAAPHFHISGACYPETHPESHNRVEDIKNLKHKVSVGCEQLITQLFFDNELFYQFQE
SCYLADIKVPILAGIMPIVNRNQALRLIKTTNTKLPRKFLAILEKYEYDPIALKEAGLAY
AIDQIVDLSTQDVAGIHLYTMNNADVAKHICQNTKNVLNGQIKAG
>A0A2N2M233|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-7|TrEMBL
QTEQESEEVFPPTQMAQKLRDGKFVIAVEMDPPRGLSTGKLIAGASLLCQAGADVIDVAD
SPMARMRMSPWAVCSLVQRKVGIETTLHFPTRGRNLLRVQGDLLAAHALEVRNIFVVMGD
PTSIGDYPGANDNYDLVPSGLIKLIKQGFNAGLDHAGTEIGQPTNFFVGCALNLNPVDME
SELKNLRRKIKSGADFILTQPIYNPDLVTRFHEAYEREDGKLPIPLIAGLLPLASARHAA
FLQQEVPGIDIPEEVHQQMAESGTLGAKAGIRLTVELVEQIKNKVQGVYLMPAFSRFDHA
AEIIEQIRGNS
>K8QQF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus rhamnosus LRHMDP2|TrEMBL
MKISQCFKDHQVISFEVFPPRKNATNIAMRPILNTLDAVKAADPDFVSVTFGATGNKPHM
GTLEVAKLIKDEFNLEPVAHLPAAQLTRAQVDAELRGFQEAGIDNILALRGDIPKSGRVS
EDFPYACNLIEHIHQVGDFDVVGACYPEKHPDSPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYQFRERAALAGINVPIEAGIMPVINEHQIERMATMAGVHLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGIDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A4U1AJM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila sp. IMCC35006|TrEMBL
MHISEIFKQNPITFSFELFPPKSKEAAEQLYATISDLSPLELAYVSVTYGAGGSTRDLTH
DLVLRIQKETDLTVVSHLTCVGSTRDEIRSILDTYASSGIENILALRGDPPQGQGPFEPV
EGGFRYAFELVEFIRKHYPKMGIGVAGFPEGHPETPNRLQEIDHLKAKVDAGADYICTQL
FFDNNEFYDFCERCELAGIRVPIVAGVAPITSVKLMKRMAEVSAGTRFPASLIKAMHRAE
DEEHEAKVGIHWATEQVRDLIDHNTRGIHLYTLNKSNATRQIYDSLGVTTTRSFV
>A0A1C2GIE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. PPCGB 2223|TrEMBL
MKITEHINNAKGKTLFSFELLPPIKGSSIQGIFNAIDPLMELNPPFIDVTSLREDHIYKE
HPNGLLEKVITRKRPGTVAVCAAIMNKYKVDAVPHLICGGFTKEETEYALIDLQFLGIDN
VLVLRGDARKADSGFVPTPGGHAYATDLLGQVVNMNNGIYLHGDVESPYKTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGANFIVTQMFFDNQKYFDFVNNCRANGINVPIIPGLK
PITVSKQLISLSKIFHIDIPEALTEAITEAKTKEDVREVGIQWMIQQCKELVKFGVPVLH
FYTMGNPEPTKHIAQAVF
>A0A1S7U3W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium salinitolerans str. Hayward 0363|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNAEMESQLWETVDELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIADGDLPTAAHLTCVDASRDEVHQVVEEFRNAGVRHFVALRGDPSTGIGTAYQ
PHPEGYENAAALVKGLRDIADFEISVSAYPEKHPESASEAIDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A062X759|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. BMG5.23|TrEMBL
MAAVRSLSTQPTTMGEYLATGRASFSFEFFPPKTPDGERQLWTALRQIEALHPSFVSVTY
GAGGSTREGTIRVTERIATDTTLTPIAHLTAVNHSVAELRRVIGNYAGVGVRNVLALRGD
PPGDPQGTWTAHPAGLRHADELVRLVRSVGGFCVGVAAFPDKHPRSVDFDSDARYLVGKF
DAGADYAITQFFFGADDYFRLVDRVRRLGCDKPIIPGIMPVTNVAQIVRMAQLSGAAFPP
ALASRLQAVADDPAAVRAIGVEVATELSRRLLDGGAPGLHFITLNRSSATREIYQAVR
>A0A3S0DFC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseriaceae bacterium|TrEMBL
EVAAYPEYHPQAATAQADIANFVHKAKAGADSAITQYFFNPDAYFAFVDEVRAQGVDIPI
VPGIMPINNYTQLARFSDACGAEIPRWLRLKLQGLGEDTASIKALGLDVITSLCEKLLAG
GAPGLHFYTLNAAPTVTSIWQRLKLS
>A0A0R2S8R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|OM182 bacterium BACL3 MAG-120507-bin80|TrEMBL
MSTDTSHFSIEFFPPRTPAGEEKLDIVHAELSKLGPEFFSVTYGAGGSTRDGTKRAVTRF
REAGSRVAPHLSFGGSDEGDILKLLHDYKEAGIDRLVCLRGDAPSGMGSASLYRYANELV
EFVRKETGDHFTIDVACYPEVHPQSRSVESDLEFFKAKVDAGANSAITQYFYNADAYFGF
VDDCARAGINIPIVPGIMPITNYANLARFSAACGAEIPRWLTKRLECLEQDDHALREFGL
DVVTDLCEQLLAGGAPGLHFYSMNQADSVTRLWQNLLED
>A0A4Q7F5E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium genosp. SA-3|TrEMBL
MSGAMTDVTTPGKANGQDGHLKRPAISFEFFPPKTEEMERNLWDTINRLAPLDPKFVSVT
YGAGGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRG
DPVGGIGTPYFSHPDGYQSSAELVAGIKKRHGDIEVSVSAYPEKHPEARDFEADIDTLKA
KVDAGATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARAFVTRAGTTV
PDWFAAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLG
IRAKSAQKAA
>A0A7D4P161|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia mollaretii (strain ATCC 43969 / DSM 18520 / CIP 103324 / CNY 7263 / WAIP 204)|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLRDIAADYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A1C0Y5Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caryophanon tenue|TrEMBL
MKLLERLKNEVLTADGAIGTVLYSYGLEYCHEEMNLQRPELIEKIHSEYIAAGADVIQTN
SYGANAIKLARYGLEEDVEAINKAAIAIAKKAAAPGGQYVLATIGGIRGIRNTDVTLEEI
LTAVLVQAEALLSGQPDAVLLETYYNFEELTETVKLIRSLTDVPIIAQVSMAEPGVLQNG
LPLNDAFEQLQAIGADIVGVNCRLGPHHTIQAFETVQLPEQAFMSAYPNASLLDIEDGRV
VYESEIDYYAKAAVELRNQGVRLIGGCCGTTPKHIQAVKQALSQLEPVTEKQAKQQPVIE
LQEAEPREQQPLHEKAKTQRSIIVELDTPRHLEIEGFLDGSQQLYDAGADVVMMADNSLA
SPRISNIAMGALLKEQGIRPLTHLTCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKVG
DFPGATSVYDVSSMELISLIKQLNDGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVARL
EKKIEHGADYFISQPVYTKEKIIEIYEATKHLETPIYIGIMPVTSHKSAQFLHHEVPGIK
LSEDALSRMEACGDDKDKATAEGIAIAKELVEVAAQYFNGIYLITPFLRYDMTLELMNYI
HQLDEQQKGVQA
>U2YL21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limimaricola cinnabarinus LL-001|TrEMBL
MPVADGTDETAGLGDDDHARRDVPDLLALPVALGAARRHIGHVERGRAVLPDTGHFGGNP
GEILNHRRQGAAPGAGYAGREDRFDKPVTPRNPQPAFIEPCALALLGVEHLVLDGIVDHA
GDDLALVFERDGDRPMRHAVQEIGGAVERIDDPAPGRVLALDRAAFFAQETIGRPRFHQR
LAHGLLGLTVGTGDEVARPLGRDLQLLDLGKILEQRATGAAGGLHHHVEIGGTGHRGLLG
LGLSGPRGPEMSRIKGPPLRAIRARGQRRRLAPLQLHRLLPRQPGEMGDIGPRRVVRAGR
GKEPAGLALCRQRPGHEIGVVPQLSHDPIGQHRDPAVRGHEKQDHRRQLNLPDGGGLHLR
GEQKLGEHVEPRALHRIGNQHLLREIARLDKGLLGQRVHRRGDEDRLVIEKRREIGLGQL
FGIGGDHQIDHLAPERGQRVEGEAGADIDIDLGPGLAELFQHRQQPFEAGVAFDRDMHAP
RLARDQPGELGLQIGDARQDVLGGGQKLHPGGRELERLGAAHEKLDPGLILDPLDLMRQR
RLCYVEQVGRPRQTAGVMDRLDRAQMAELDMQVKLMIVVRVMNLSHTTSSATRSTAHRRP
SMTRPAVSFEFFPPKNIEGSFRLWDTVQALAPMGPEFVSVTYGAGGTTRQLTHEAVDAIH
KKAGLRVAAHLTCVEATRAETLDIVNGYAKAGVEEIVALRGDPPKGSGGFTAHPQGFSGS
VELIETLAAMEKFRIRVGAYPERHPDAAHELADVEHLKRKFDAGAHSAITQFFFEADTFF
RFRDACEKAGIKGQIIPGILPIENWKGARKFAAMCGTSIPQVVADGFEHAADQAEADMLA
TALATELCDKLIAGGAEHLHFYTLNKPDLTRDVCHALGITPKAALSEVA
>A0A2R4ZMZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurococcaceae archaeon AG1|TrEMBL
MCEDERLTCVWIMAYYTAIKRGTVDRMFTLKLDSGFKINNYYPIPRRPRGAVEKILGGRV
FMVYEYTPKPYSSPLNIPSELRGIASIYDGVDFVDNPGGYPIPSSLPYASIAKNSYRDMH
VSIQLTARNRDRSQIASEILAASLSGIDAIVATTGDLDDSGKDVWDLDAPRIIYLARLIL
DLGLDHLGRRVGLGGEGMAIACSVNINARPLEPEILKLRVKRRAGAEIVITQPVFEPEIL
GRFRRMTKDLLGEEMPMILGIIPIMSRKIASFFQNKVGIKIPEKISKILSSERIDKEELL
KTNIEVIENIAREVAHNAFYISAFGDHKLGYEIGRTIRRALS
>J2MZR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM102|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQIITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1B4HPU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia metallica|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATRTICERLDG
>A0A1G3PDV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium GWF1_31_7|TrEMBL
MNNLKEKQLKNNNKPLLLYGITPPRKDIDENKLQEINAKRIDRIKKLPIDGLIVYDVQDE
SLRNNEKRPFPYIATIDAFSYVNLYLNSLSCDKIIYKPVSNQDAGEFKKWLNSPGILNNN
YVFVGSPSTKLKPQMSLDDAYKIIAVEKPEITFGAIMIPERHQVKNNEHERVINKSNQGA
SFFISQCVYNIELTKNYLSDYYYFCINNSIAIQRQVFTFTPCGSVNTLNFMKWLGISIPK
WLENELYNSANILEKSIEENLKNIAEIIKFCKEKNIPYGINIESVSIKKEEIDASIYMIE
TASAMLKR
>A0A1V4S8S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4484_190.1|TrEMBL
MSLEAKIKSGEFVVLGEFEPPKGADFSRLLKNARQIKGRVDAVMVPEMGNAVMKASSLGG
CAFLQSHGIETVFQVCCRDRNRLALQADILAATALGIPNIMAVPGEDITYGDHPQARLVN
DLNLIELLETMQKLQNGKDMAGVELSGVPNFCTGSSVNAGALGGVKDIEMQNLNKMTNLG
VQFLITTPVFDLHRFQQFMKHVDTTKGAVIPTVLLLKSAGMARYIDRNIKSISIPKEIIR
DIQKAPDKLKQCINLAAETIGHLKDMGMAGVMVSTVGWEDKLPQVLDAAKL
>G6C3S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium sp. oral taxon 370 str. F0437|TrEMBL
MKIADIYKSKSLTTSFEVFPPNEKVGLEEVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNEVESVAHFTCIGSKKEEIDRVLEDLERNNIENILALRGDYPVDRELESGD
FNYAKDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIIPVTNAKQIKKITSLSSCTIPKKFLKILEKYEDNSS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRK
>X5QMT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSJC285A00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLRPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A5D9D320|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. B1(2019)|TrEMBL
MRSETARRDGDIRLSFEFFPPKNAEMESQLWETVDELKKWNPDFVSVTYGAGGSTKAPTL
DAVRRMIADGHLPTAAHLTCVDASRDEVHQVVEEFRNAGVRHFVALRGDPSTGIGTAYQP
HPEGYENAAALVKGLRDIADFEISVSAYPEKHPESASEAIDIDMLKRKADNGATRALTQF
FFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYDD
DLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A7W0NVC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
VPGIMPIWDYSKVARFSAGCGAEIPQWLQKRMEAYGDDAASQRELGIEFVTDLCQRLLDA
GAPGLHFYSLNRAEPTSTIWSNLGLKPTAG
>A0A6L9JKC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus luminescens subsp. laumondii|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSINRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEQTGLEAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGD
LPENSEKPKMYGSDLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFRQLKRFAVMTNVRIPSWMTRMFD
GLDDDPESANLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A3M1EIL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineae bacterium|TrEMBL
MALFSPPRYQPPFSPMQRQSFPMRLFSTVEQAIKGPLFGCRMCGNCILQETAFVCPMTCP
KGLRNGLCGGATPEACEVDPSRPCTWYTIYHRAEKMGRLDKLLEINAPLDGERVGHETWL
DLLKKWREWDDSPRLLEFFTNRQKFNKDWDHFFYRLRQPDWWQGDAAYHPPAYEEPISLL
EANLRTGQFTVTAEIAPPLGASGDIILKKVGWLKGYVAAANFTDNASASARMNSMASSKI
CLDAGLEPVMQLQARDRSRVVIESDAMGAAGLGIRNILCLSGDHHRFGPAPITKPDQFDM
DSVQILWMLRRMRDEGKYLDGRNIKRRPEFFLGAAASPFGAPPPYEAIRAEKKINAGAQF
IQTQPIFDYDRFLEWLEALDKRNLLDKVYILPGLIPLKSARAAHFMADDVPGVVVPPEIV
RRMDNAGDKEGQQEEGVAIALEMIEKLMKTPGINGMHVMAVHWEAIVPRLLDEAGVPRPA
IQTWPLPEETPSEAQPEPAPAG
>A0A2V7PAZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MPITLRELLDDGKVHVLDGAMGTMLYSKGFFLNVCYDELNVKQPKLVKDVHEAYVRAGAE
IIETNTFGANPVKLGSYGLADDTETINKAAAELARGAAAGHASVVGAIGPLGVRIEPFGP
TSREEAYAHFQRQARGLLAGGVDGFILETFSDLDEIHEALRAVRGVSDLPVIAQMTVGDD
GLTHYGTAPETFAKQLTVWGADAVGVNCSVGPAGVLEAVEKLVKATDRPISAVPNAGLPK
DVGDRKIYLASPEYMASYARRMIEAGARLVGGCCGTTPEHIKKIRDYVASVVPRHQPIVV
SRDVIAAPAGVEEVPLARRSAWGAKLARGELVTSVEIVPPKGVDATPMLEQSRALKAAGV
DAVNVPDGPRAQSRMGVLPSAILIQREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRN
ILIITGDPPKMGPYPEATAVFDIDSIGLTNLVYRLNHGLDPGNNPIGKPTEWAIGVGVNP
GAVDLDRELSRYAWKVDAGAEFAVTQPVFDPEQLEEFLKRAEQFKIPIVAGIWPLISLRN
AEFLANEVPGVSVPESVLARMRKAQEKGKEAALAEGVKIAREMFQRVKGMVQGVQVSAPF
GRVEVALEVFG
>A0A2V7KGK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYGKGFFLNVCYDELNLKQPRLVQEVHAAYVRAGAEILETNTFGANPLKLNSYGLA
DETEKINRTAAELARAAAGGKASVVGAIGPLGIRIEPFGSTSKAEAEAVFARQAQGLLAG
GVDGFILETFSDLDEMHAALNAVRAASDLPVVCQMTIGTDGLTYYGTDPDTYTKQLAAWG
ADVIGVNCSVGPAGVLEAVEKMVKATDKPISAQPNAGLPKDVGDRKIYLASPEYMASYAR
RMIETGARFVGGCCGSTPEHIKKIRDYVASVVPRQPSVVVSRAQVHAPAGVKPVPLAEKS
AWGAKLARGALVTSVEIVPPKGVDPKPMLEQCRALKAAGVDAVNVPDGPRAQSRMGVLPS
ALLIEREVGIETVIHYCCRDRNLLGMLSDIIGAHAAGLRNILIITGDPPKMGPYPDATAV
FDIDSIGLTNLVYRLNQGLDPGNNPLGGMTKWAIGVGVNPGATDKDRELSRFAWKVDAGA
EFAVTQPVFDARQLEAFLKQVEQFQTPIVAGIWPLISLRNAEFLANEVPGVSVPDEVLQR
MRKAQEKGKEAALAEGVAIARDMFTRVKQMVQGVQVSAPFGRVEVALQVFQ
>A0A7S1AMN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noctiluca scintillans|TrEMBL
ICNLVALRGDPPRGQDKWEATEGGFTCALDLVNYVRANHGDYFSIAVAGYPEGHPDAIEE
VEGGLAALTEPEKRRARVAKNESGVEVVTVCRDVNFEKEMKYLKEKIDAGSQCVITQMFL
DAEVYLDFVKICR
>A0A847Z2T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacteriaceae bacterium|TrEMBL
MEISKLFKEKKIVYSFEIFPPKLNSPIEVIYDTLSHLENLKHDYLSVTYGAGGSDVKSRT
CDIASIIKNKYNIEPLSHLTCINSKKDEVRQVLDALRDGNVTNILAMRGDKQPGTIVADD
FKFSYHLMDFIARNGGFNIAGACYPEGHPECESLTKDIEYMKKKQDCGAEFFITQMFFDN
GLFYEFINKARKTGVTAPVQVGIMPITSTKQIERIVYLSGARIPQKLSKLLARYGSNKEA
MTQAGIIYATEQIMDLVENNVQGIHIYTMNNLNIARRITENINSVISMENTSYLG
>A0A352FQ56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MQTFKDLLDSDRAYIFDGAMGTMLYSKGIYINRSYDELNLAAPDLVREVHSEYVRAGADI
IETNTFGANVNKLQPYGLEANAHEINVKAARIAREAAGDRALVAGAVGPLGLRIEPYGPT
SFDEARQMFSDQISALLEGGVDLFVLETFSDISELHQAIKAVHDLCDLPIVAQVTIQMDG
NTLFGATPEIFTSRIAEWGADVIGLNCGVGPAIVLNAIEKMHALTDKKLSAQPNAGLPRD
VGGRQIYMCSPEYMAEYSRRIIQAGAKFVGGCCGSTPAHIKMIADAIRQFHPRTQQVSVA
EAVKVSVHELKPPDVTVVPAEERSNWARKIARGEFVTTVEVLPPKGCSPAKTLDAIRLLK
DAGVDGVNIPDGPRAQTRMGAMATAVMVQQQIGIEAVLHYCCRDRNLLGMMSDILGAQAL
GVRNLLLITGDPPKMGPYPDATAVFDIDAIGLTNMVNKLNHGLDIGNNPIGEPTSFSIGV
GVNPGAVNMEEELRRFEWKIEAGAEYAITQPVFDVQQLRDFLKRIEHCRIPIVAGIWPLV
SFRNAEFLHNEVPGVHVTPEIMDRMRAASAISKEAGRDEGLKIARESLAEVRDLIQGVQV
SAPFGNVKYALEVFSVLPEFSSQKEAAAPAA
>A0A0R2QCD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobium sp. BACL27 MAG-120823-bin4|TrEMBL
MSILSRLKKPSVKVTPAVKELVSNMRYELIPMKSIEQGILDLPTGAPVSVTCSPAKGISA
TQEISARLIAAGHEVVPHFAARLVESREHVTKLASWVREQGIKEVFLIAGDAENPAGPYQ
DGSILLKKPSVKVTPAVKELVSNMRYELIPMKSIEQGILDLPTGAPVSVTCSPAKGISAT
QEISARLIAAGHEVVPHFAARLVESREHVTKLASWVREQGIKEVFLIAGDAENPAGPYQD
GVELLRDFLDSNSGVERVGFGSYPDGHAFISREDLSTALHHKQKLLEEAGVQGLASTQMC
FDVPLIRSWLEQERNNGFKIPIQLGVPGVVDRTRLMTLGVRVGVGQSMRYLSKNKTSIIK
MLSPGGYDPTELVAGLAKDAKRLNIVGLHSFTFNSVADTAVWQREVMAG
>A0A2V7SSB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTSPALARLVDPEALVLFDGAMGTMLYAKGVFINQCYDELNVRAPDLVRDVHRAYVKAGA
EVLETNSFGANRLKLSQFGLAEQVHELNRRAAELAREAAEQGRDVLVAGAVGPLGVRIEP
YGPTSHDEARAYFREQLEGLKAGGADCFILETFGDLDELGQAIAAARDVDPTMPVVAQMT
IGADGLTPYGATPEDVVHALDRFGADVIGLNCSVGPQTILEAIERMAPLTRKKLSAQPNA
GMPRDVGGRSMYMASAEYMAEYARHLVHAGAKVVGGCCGTTPEHIRAMCEFVRPLSPRFA
QPSGGVSTVAAPPVLRDVAHRAPDVQAVPLAQRSKWGAKLAAGAFVTSVEIVPPRGVDAT
RMLTDVRKLKVANVDAVNVPDGPRAQSRMGALLTSLLIEQQVGIETVTHYACRDRNLLGM
LSDLLGAAAIGLRNLLLITGDPPKMGPYPSATAVFDIDAIGLTNLVRNLNHGRDPGDNAI
GAPTQFVIGVGVNPAPIDLAHELKRFAWKVEAGAEFAVTQPVFDATQLENFLRRTDGQRP
PIVAGIWPLVSVRNAEFLANEVPGVSVPDAVIERMRKASERSKEHAVAEGIAIAREMLDR
VRGGVQGVQVSAPFGKVELALEVFGDTLVSIVPEPTVVRASVSA
>A0A353CBT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MKNFRELLASDQVIVFDGAMGTRLYDKGIYINRSYDELNLTNPELVRDVHEEYIKAGADV
IETNSFGATRNKLQPYGLEGKLSEINTAAARIAREAAGDRVFVAGAIGPLGIRIEPFGPT
SFDEARDLFKEQAKGLLEGGVDLFILETFSELPVIEQAIRAIKEICDLPIIAQMTIQADL
NTTFGTTPETFTQRLDELGVDVIGLNCGMGPTHLLSALERMRSVTDKPLSAQPNAGLPRD
VQGRQFYMGSPEYMATFAKRFVQAGARFVGGCCGTTPTHVKLIADSIRSISPRQTNASTG
ARPAPVIELKPDDVLVVDPEDRSRWSRKIARGEFVTSVEVLPPKGCDAEATMNSIRLLES
AGVDAVNIPDGPRAQTRMSAQATAVLVERDIGIESVLHYCCRDRNLLGMMSDLLGAAALG
LHNLLIITGDPPKMGPYPDATAVFDIDSIGLTNMANKLNHGLDIGNNPIGKPTAFSIGVG
VNPGAVNLDEEIKRFEWKVEAGAEYAITQPVFDTAQLRSFIEKINHLRVPIIAGIWPLVS
YRNAEFLHNEVPGVNVTPEILERMRAASEKGKEDAREEGIAIARESLLEVRDIIAGVQVS
APFGNVKYALQVFDVLEEFRSSGKDSKL
>S0FT88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminiclostridium cellobioparum subsp. termitidis CT1112|TrEMBL
MKLNVTKLFENKDYFLFDGAMGTYYSSKHDNSIACETANLNDGQTILRIHREYIEAGANA
IKTNTFAANRFSLACEQPEVEQIIKKGWEIANAAVRDREAAVFADIGPIPIPQGQEEETE
YKKLADIFLQCGAENFLFETFSRYDIILELAAHIRLKKPDAVIIASFAVYPDGYSKEGLF
FQDIFKKVSSSGLVNACGFNCISGPAHMCRLVGQLDIKGRLVTVMPNSGYPSSERGRTVY
VDNSDYFAEKMLELKKLGVKILGGCCGTTPHHIAVTAKLLAGSGSAAGNTEQQADKQVLP
ANRKPLIQKLIAEKKPILVEIDPPFDTNWEYMLRDAFLLKTAGADMITIADSPLAKSRAD
SSMMAARLQRESGLPAMPHITCRDRNLLGIKATLLGLNIEGIRNVLLVTGDPIAIIERKD
VKGVYSMNSSNLANYVSSLNDNVFGEASFEIGGALNVNAPNFDAELRRSVKKIENGISFF
LTQAIYTETAVNNAVKAFEVLKVPVFAGIMPIVGYKNAQFINNEVPGIDIDAATVESFRD
KSREESEILGIEHSMKCINKLYEHVSGFYIMTPLKRIHVVCELIKRIKEKKV
>A0A7M2GMG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium fuliginis (strain ATCC 27551)|TrEMBL
MALNAIDLTVDRSPIDLLSGYSLEITAKDGEALRSAAPRIPPGTSISVTALPDEDVADRL
AAIRLVRELGFEPIPHISATAVTSAEALDDYLAAVTGQAGVRRCFVIAGDLATPRGPYCD
SSALIASGALERHGIRAVGVGGHPDGHPHMTPEECWSVLAAKCAAISERGMTPFVVTQFA
FDGVHIAEWLGDLRRRGITAEVRLGIPGPAGIKTLLRFAARCGVGASASVLARYGISLGK
LLGSAGPDKLVDLLRSRLDASHQPVGLHFYPFGGMEKTIAWITDYKDRT
>A0A8G0CMS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia salina|TrEMBL
MIDDNLRASRKTADQRPALQISFEFFPPKTDAMEERFWDSIAKLAPLSPRFVSVTYGAGG
STRERTLRMVSRITNDTGVPAAAHLTCVGATRDEVDAVVRGYQQAGVNSIVALRGDPPEG
VGQPFTPHPQGYQNAADLVAGIRKIGDFDISVAAYPEKHPQSTDWGADIDNLKRKIDAGA
DRAITQMFFSNADYLRYVERARKAGIIAPIVPGIQPIHSFKQISGFAARCGASIPGWLAE
RFEGLDEDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRP
>A0A2L2MD87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces dengpaensis|TrEMBL
MAVHTSPGTAGDPASGAAVRSLIGDAAIEVIPLRSADEKLKAIPEGTTVSVTTSAKLGLG
RTLEFAERAVRAGFNVVPHLAARQLTGEEELRRFIGRLGELGISRLYLIGGDVTPPAGPY
DSSLQVLEAMQRMDHGLRRIGVACYPEGHPKISDAALSEALRDKQPYAAYMVSQLCFSPE
VLVSWLRRVRGEGITLPLLIGLAAPMQVTKLIKLGPQIGVGTSVRYLAKQHGFIGNVLKG
GAYRPESLLLEIGDAVTSPELGIEGLHLFSFNQVEETVRWQRDITAASSGAAR
>A0A436K552|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.002.03.1.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>R6NFI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium CAG:364|TrEMBL
MKLSDAMREKMLLSFELFPPKTDKGMENLPGTIEHLCKYKPEYISCTYGAGGTNVGKNMD
VCKMIKDAGTIPVTHFTCIGNTAEGIKDQLQNYLDNGVDHMLALRGDLPFGWTGTGGDFA
YATDLVAYVRKEFGDKIEIAVAGSPEGHISCRSLEADIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRCAGITMPVDVGIMPILDQAATINMALSRNACVMPRELCEIISKNWIFPN
PFVQDPFDADVEGKKARFKEAGIEYTIRQIDEYRACGIDGIHLYALNKWKDVSEIIDRSG
LRTLV
>A0A1Q7AXA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_2_20CM_2_72_6|TrEMBL
MALGLPSLMPGGQPSIGELIGAPTPTFSFEFFPPKDEAMERQLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTIRNILAIRGDPPGNPQGEWIRHPQGVDYAEDLVRLVKESGDFCV
GVAAFPYKHPRSADIESDTDYFIRKCRAGADFAITQMVFDADDYLRLRDRVAAAGCDTPI
VPGVMPITTMGTIGRSEQLSGAPFPPHLLVKFERVKDDPAAVRRMGIEQCGEMCDRLLSE
GVPGIHFITLNRSTATREVWQQLALGAQT
>Q0RJI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia alni (strain ACN14a)|TrEMBL
MRCGCGRWIVASYPVRMQDSTAGHERPARGFELICEIEPPTRPDLTHARHQIGVLSPVTD
AFLIPDNHIGRATVSSIAVAHEVQAMGGRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFL
FVRGDKPTAGNRTSDLTVRAMMDEARAASEGPVFADMPAFRVGAAAGLRPLPAWKRAADF
LFVQVSYSVDALLRWRDAHPVELPVYAGVMVLASAGMARRLAATIPDIDIPDDLVHAVER
DQAAGVEAACDQVLRLRDSGAFAGVHLVPVSRYRQVATRLEDLL
>A0A3D2WF82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MPLEACSAWGQKLSRGEPVVSVEVLPPRGWDRNAIVEPARELKEAGVDSLAIVDGPRSRS
RMGALSAAVIVEQEVGIEAMVHYTCRDRNMLGMISDLLGAAAVGIRNLLVVSGDPSVHGP
YPDMTEVFDIDSIGLTNVVRGLNQGIDPAGNSIGDPTKFVQGVVANPSALDLEREVTRFR
YKVEAGASFVVTQPIFNPESLEKFLDKIHQWEIPVVAGIWPFLNQRNAEFLANEVPGATV
PEKIVDRMRKAQISGDEEALNEGVEIAAEMIDAIRPLVQGLHLSAPSRRADVALRVLHEA
GVSTNTNSSLFGV
>A0A3B9DPA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
VIGVRVSQVAVDQDREAGRLNWKVDAGADFVITRPVFDAEQLHSFLERVPELSVPIIASL
RPLTSLREAEFLHNEIPGIQIPDRVLARIATAEAHGEDAARAEGVSIAMEAFAAVRDSIA
GVHIHVADGNLDGALELLSEIRDSA
>A0A5D6W7J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp. mPRGC5|TrEMBL
MKRVSVELVPRDEESLRAELALLQQYKDKIDVINIPDLLRFETRSWQGAAMAKEYFPQAM
PHIRAMDINLAEELPMKDYLREHDIREVLVIEGDPPQRMTHAVYPTESTDVIRKFREEMP
EIDVYAGIDQYRSSMREELYRVHRKVQAGAKGFFTQPFYDMRYLEMYADMLDGLDVYWGV
SPVMTAGSQSYWERKNNVVFPKSFEPGLEWSVAFSREVKDWAEKNGENIYLMPIRTNLEE
YLAGVFATL
>A0A2U2BUN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinicauda salina|TrEMBL
MTLTAIHARDADSVPKFSFEFFPPKTDEAEERLWDSISRLEPLNPSFVSVTYGAGGSTRD
RTHRTVKRIVQETDLKPAAHLTCVDATREEIDDVIRDYWAAGVRHIVALRGDPPEGIGEK
YVPHEGGYANAAELAGGIKKIGDFEISVGCYPEKHPESPSYDYDIDLLKQKIDNGATRAI
TQFFFEPDVYFRYLERVRAAGIDIPIVPGIMLQSNFKGLKRMAGMCGSAIPSWMDDLYEG
LDDDVETRKMVTANVAAELCTKLAEGGVDQFHLYTLNRAELALCTTRLLGATPAEMEAA
>F9U825|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiocapsa marina 5811|TrEMBL
MPPVSQQPPTYSVELFPPKTPEGMEKLKREIAQLNSVSPGYFSVTYGAGGSTRERTFETV
DWLRGHAIETAPHIACVGSARAEIREIVGRYREQGIRRLVALRGDLPSGMGGGTGGDFRY
ANELVSFIREEFGDTFKIEVAAYPEYHPQSGSPERDLANFKRKVEAGADAAITQYFYNPD
AYFAFIESCDRVGVTLPIIPGIMPITNYTQLARFSDACGAEIPRWVRRRLEGYGDDVESL
RDFGHEVVLNLCRRLIDGGAPGLHFYTMNQSGPTLRLWRDLALPLPA
>W1UZQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella dispar DORA_11|TrEMBL
MTLREKHQQGQFTITVELDPPKSSSAEKTFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKKIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDSPTNFYIGATGNPGAPDLEIERQKLAAKIQNGA
HFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
MEKGGKEAGTEIAIETLEQIKKMAAGVHIMPLNDIDTTLYIIDHV
>A0A1S2MNF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. LCT-H4|TrEMBL
MSQLLNKLKNNILVADGAIGTILYSEGLDTCPEAYNLTHPDKVQRIHQSYIEAGADIIQT
NTYGANFEKLKVFGLEHKVKDIHQAAVQIAKQAANNDTFILGTVGGFRGIKQEDLGLSAI
QYHTEIQVDTLVEAGVDGLLFETYYDLEELTNIIKATRRKYDIPIIAQLTALNTNYLRDG
SEINTALKQVAASGADIIGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSEF
RYSDNAAYFGKVAQQLINEGVRLIGGCCGTTPEHIQFIKSSIKDLKPVSNKKVIPITKQS
SRSNTTSQQQTLTSKVKQHPTIIVELDTPKHLDTDKFFRNIKKLDDANIDAVTLADNSLA
TVRISNIAAASIIKQQYAIEPLVHITCRDRNLIGLQSHLLGLSLLGVNEILTITGDPSKI
GHLPGASNVYDVNSKGLTEIALRFNKGINTDGDALKTKTNFNIAGAFDPNVKKLDGAVRR
LEKKLESGMNYFITQPVYSAEKIKEVYEATKHLDAPFFIGIMPVTSYKNALFLHNEVPGI
KLSDEILEQFEAVKNDKAKTKALSLELSKDLIDTVHEYFNGLYLITPFQSVEYTLELAAY
SKQITSNKQEAIL
>A0A846RR34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter pigmenti|TrEMBL
MSPPSKSAHSVGPPSLEPYHALSYELWPPRTPNAAETLWRTIRELEQTSPDYVSVTYGAS
GSNRDTAFELLGRLLGETSLRPLAHLTCVGHSRENLENLVDELITRGIRGILALRGDAPK
DTTLPPGDLSYASDLVRLVRETERRRTAHLCAGRLAVGVAAYATKHPESPSFDHDVEALL
AKQAAGADFAITQLFFFPDQFQRLVAAARRAGVEIPIIPGLMPPTSVRRLDRASELAGLE
MDHRLRDRLAAADDDAARRRIGVQATVDLANAALDAGAPGIHLYTFNEHAAALDVLEHLD
LRRPPVRGGLGRTA
>A0A6L4YCW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKSESKLEQILTKGEFAVTSECGPPRGADAEVIRKKGELLKGFVDGVNVTDNQTSVVRMS
SISSCVILKGLGLNPIMQMVTRDRNRIAIQSDILGAAALGINNILCLTGDHQKFGDHASA
KNVFDMDSIQLVQTVKLMRDEGKFLGGEELKGSPKMFIGAAENPFADPFEIRVPRLAKKV
AAGVDFIQTQCIYNLPKFEKWMKLVRDRGLHERVHILGGVTPFKSVGMANYMKKSVPGMD
VPDELIERMKAAPKEKKAEEGINICIETIQRLREIEGIHGVHVMAIEWEEMVSEIVKRAG
LFPRPHIEG
>A0A7C4YRA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MEKKTFSEKLKEGKFVITSEIGPPKGTNIEPHLKEAEHIKDKVDAFNVTDLQSSVMRLGS
LATCRLLVERGLEPIFQLTCRDRNRLALQSDLLSASVLGIRNVLCLTGDHTTLGDHPDAK
PVFDLDAVSLLKVATDLMSGKDMKGNDLDGKPEFFLGAVVSPGYEPVELQIMKMEKKIEA
GARFFQTQAVYDLSSFEKFMKMVEKYNVPVLGGIVLLKSAGMAKFMNEKVAGVSVPDRYI
NMMAQAKKEERVKVSVKIAAELIKGMKGLCQGIHIMPLGWEKYVPMVLEESQL
>A0A7C6ESB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MQRWLEAIQERVLVADGAMGTLLYARGVAFHHCFDALNLWQPEMVRRVHRDYLEAGAEIL
ESNTFGANRFKLGKYGLEDRVREIARQGVRIAREVAGDRAWVAGSVGPLGKPLAPVGIVT
PEEAREAFREQIEGLVEGGADLIILETFNDLRELELALTAAREVTDLPVIAQITVTEEGK
TIVGDKPREVARRLEELGAAVIGVNCSVGPQVVFDAVEQMVAAVDVYVSAMPNAGLPRLV
DGRYIYLSSPDYFGQYALRFVEIGANIVGGCCGTTPDHIAAIAKAVSGLKRRPRKSKREI
AAVEVVEEGEAKQVPRFESATRFAQRLGKEFLVSVELDPPKGIDPSRTLQAAFRLKEAGI
DAINIADSPLARPRMSPVALAHLIREHVGMDVILHLSCRDRNLIGLQSELIGAHALGIRT
VLAVTGDPPVMGDYPNATGVFDTDSIGLVHLISLLNRGVDLTGRPTEEPTAFTVGVGANP
AAVDFEREMERLQQKVERGAQFIFTQPVFDLDLLGPFLERARPLGVPIFLGILPLRNYRH
AEFLHNEIPEIKIPDHLLKRMYKAGERGFEEGIAIGREILSAARGEVDGVYLMPPFNRIE
AAIEVLKGIR
>A0A853GX72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MSGKQAISLEFFPPRDIAAQEKLVRSAKQLLALQPEYVSVTFGAGGSTRSGTADTVRLLQ
NLGCDVAPHLSCIGATRAELAEILNSYRAQGVRRIVALRGDLPSGMGGDAGELHYASELV
AFIREHSADWFQVEVAAYPEMHPQALTATADLEHFKNKVQAGAQGAITQYFFNVDAYFDF
VDRARAAGVSIPIVPGIMPITNYTQLARFSSMCGAEIPRWLRLRLTDFGDDRASIRAFGA
EFIGQLSQALLDRGAPGLHFYTLNNAEATMAIWRQLSLRDTSVAVA
>A0A7R6YL24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 131-3-5|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVCRILNETSLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A3N8LDV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Bp8963|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADIENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDREAIRAFGADV
VTGLCQRLLDAGVPGLHFYTLNGAAATKTICERLGV
>A0A7C2YA61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MDKTTPTGVASNEQPATSNQPFLEHLRHYLLVGDGAMGTMIYAQGIPLAQSFDELNLSQP
AIIQKIHRAYVDAGAQALETNSFTANRCKLARFGLEQRVVEINQAAVCLAREAAAGKAYV
LASVGPVRDRESDEIEASVMRSAFAEQITALADAGPDAIILETFNRVNELEMAVIEARRA
TDLPIIAQVVADEEGYTRDSPTGVAQHITAAFRRLRDLGANVVGINCAKGPTGILHALRE
VSLDDGLLLSAFPNAGLPAFIEGRYIYLSTPEYFAESALKLREQGVRLIGGCCGTTPDHI
RAMAAALRGLEPVRQKQAVVHLQPASLQVPAIVEPEFFKNVKKRPTIIVELDPPRDLEHE
SIMRGAVELKRAGIDALTMADSSLGITRMSNMALGYLVKQKTGLPLIIHLSCRDRNLIGL
QAELMGLYALGMDTVLALTGDPAKFGDQPGATSVYDLNSFNLITMIRKMNQGVAFSGRTM
KQASRFTVGVAFNPNVDRIETQVNRLRKKVQLGADFVMTQPIFDWRIAREIYEATREFDI
PIFVGIMPLVSGRNADFLHNEVPGIEIPLKVRERMYRFEGERARREGVTVAAEILESVLD
YFNGIYLITPFVRYEMILELVEKCRALSLRPATKRKN
>A0A6G8Q7C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacter tropicus|TrEMBL
MSFDLREMTGSGVLIGDGAMGTLLAERGVGFGHPYARANVTHPEMVAGIHEEYIRAGAGV
IETNTFSANRFKLEVHELEDRVREVNEAGARLARKAADIAGTNGSKALVLGAIGPLGRPL
CPVGPVTEAEARAVFLEQAEALLEGGADALVLETFTDLVELRLAHEAVRGLGVPIVAYKT
FVEDGETLSEGLPGRAAREISALGVDLSGSNCTVGPQRMVGIIEGMSAEVGPVAAFPNPG
LPQLVDGKVRFRRDVDHFALYGRKLAEAGARLVGGCCGTTPEHVKALADALRDFRPGTTP
NRGVSVRTVEEEKPQEVLDGPSTDLAEKLRTGFAVAVEVDLPRGNDITRVVEASRRLKER
GVDAIDISDGARARLRMHPVAAARIVQEEVGIEVVAHISCRDRNIIGLQADFLGAAALGV
KNILAVTGDPTQIGDYPEATGVFDTDSAGLVHILSRMNRGEDLAGNSIGGPAGFLIGSAF
NPTAEDLDGEIEKLRRKIGAGAHAFWTQPVFEIGALEVALERLGDLDPCLLLGLMPLRSA
RQAEFLHHEVPGVDIPKPVREKLATLSPEDAPKYGVEVAQNILAKAQPLVNGAYIMPPAS
APDLAGEVIEAISTQRSAVG
>A0A1F9NKT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium GWB2_56_26|TrEMBL
MKSGSNLEKVLAAGHFSVTAECGPPRGADPEVVRKKAAYVKGNVDACNVTDNQTSVVRMS
SLAGCLLIKEEGIEPLIQMVVRDRNRIALQSDLLGASAMGVRNILCLSGDHQKFGDDPQA
KNVFDIDSMQFIHLVKSMRDEGTFPSGKKLDGAPKFFIGCAVNPFADPFEIRVPRLKLKV
EAGADFVQTQCIYNMKKFKEYLELAKKQGLHEKVKILAGVTPLKSAGMAKFMKKMVAGMD
IPDEVINRIAAEPKEKQAEKGIEMCIELIQELKEMEGIAGVHVMAIEWEEKLHEIIGGAG
LLPRPVVE
>A0A5Q2RJ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomarinicola tropica|TrEMBL
MRDLLAAGPSVSFEFFPPKTDEAERQLQLTIKELEHLSPSFVSVTYGAGGSTRERTRDIV
IGIERDTSLTAMAHLTCVGHRRHEITELLEEYEQGGVSNILALAGDPPTDGEPAEGDFAY
ALELVELVREAGDFSVGVAAHPEGHPRSPDRDSDLRHLAAKLTAADFGVTQFFFRAEDYL
RMRDGLVERGCDTPVIPGIMPVTNARQVQRFAELSGAAFPADLAARLESVADDAVEVRRI
GVEVATELCRTLLDEGVPGLHFYTLNRSTATREIAANLGLARP
>A0A1Q9AM74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium rhizosphaerae|TrEMBL
MAPQTLHPARRAALTLSFEFFPPKNEEMERQLLETAEALKVYAPEFVSVTYGAGGSTKAR
SIDTVRRLIADHGLTNTAAHLTCVGAARAEVDSVIDSFMAAGVTRFVALRGDAPGGAGVA
YQPHPEGYENAAALVGALARRGVRSIAVSAYPEKHPESADVAADIDMLKRKVDNGATQAL
TQFFFDNDDFERYLERVRAAGITIPIIPGILPINNLNQVIKFAGLCGARVPQVLIDRLGP
LEEAPEERFREATLIAAEQIVDLAQRGISSFHLYTMNRTPLISAVCDMVQFARVDAASPA
A
>A0A1E5F1X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio tasmaniensis 1F-187|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A2H0G0R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium CG18_big_fil_WC_8_21_14_2_50_58_12|TrEMBL
MTTPLPILSFEFFPPKTPEGMDKLRATRKQLAQLNPEFFSVTFGAGGSTRDLTLETVIEI
QREGHEAAPHLSCIGSTRENIRAILNEYKSHGIRHIVALRGDMPSGMACAGEFRYANELV
EFIRAETGDWYHIEVAAYPEFHPQAISAQADLVNFKRKVEAGANAAITQYFYNADAYFNF
VDECQAMGITIPIVPGIMPIGNFTQLARFSDACGAEIPRWLRLKLQGYGDDTAAIRACGL
DVVTSLCDRLLKGGAPGLHFYTLNQAGLISTIWQRLGL
>A0A522YTD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MLIPELFTKGRPVFSFEFFLPKAPEDMGKFKETVRELKALGPDFVTITYGAGGSGRAQTV
ETAGMIKAELGIETASHLTCVAHTKAEVEAVLTRLKTLRIENIVALRGDAPKDGSALPVH
QRELPYAADLVRLIKARGGFAMAVAGYPEKHPESPSPEADLKRLKEKADAGGDWVITQLF
FDNKDYFDFVRRARAAGVTRPIVPGIMPVTGFAQTKRFTEMCGAKLPPELLAGLAPIAED
KEAVVRFGVDWATRQCRALLAGGAPGIHFYTLNRSHSTEKVLENLRRG
>A0A1J5D8T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG2_30_43_15|TrEMBL
MPKSFKEALESGKFVVTAEVGPPKGTDIEEMLHHIDLLKDKVDGLNVTDNQSSVMRLSSI
SVSHIIREKGGEPILQMTCRDRNRLALESDLISANILGVDNVLCLTGDYITMGDHVEAMP
VFDLDSVLLLKTVRLLESGKDSGGNELKGSARFCAGAIVTPEANPIEPQLLKFEKKIKAG
AEFFQTQAIYDLDNFKKFMRYARQFNVKILAGIVLLVSAGMARYMNANVPGIFVPKALID
EMAGTEKGKALEKGIEIAGRMIKTLKDENICDGVHIMAIGKEGKVPDILAAAGLV
>A0A2E3B6G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKVKLINKKFIKSIEIIPSRYKIDNLLLDKILKYNKSFDFLDIACTPMANLRISPLSFAH
GLIMKGIKPNKLIINFSTRDKNTLALQSEILGALSMKVNKLLLIKGDKINIGNSKKSKEV
FEINTNELISLVNKLNSGKDYSNNSLGYKTDFLIGSTLNIDLPFKKIEKNLIKRNNIGSN
FFITQPLYSELDFINLSKLSALSSNKILAGIFPIKNKKTFKNLNNKINGINKDNSLFKEL
KKNKEEDYLKISTEYLIDLLIKYKKNLDGIHIMTAGDIKLASQISSKI
>G0VEA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naumovozyma castellii (strain ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC 1992 / NRRL Y-12630)|TrEMBL
MRITEKLQAHQRESDKPTFSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDVTWNAGGG
RLSQLSTDLVATAQSVLGLETCMHLTCTNMPVSQIDDALKSAYDSGCQNILALRGDPPIN
STKWEAVEGGFNYAKDLIKYIRSKYGDHFDIGVAGYPERHPEEEDELLNLKYLKEKIDAG
GNFIITQMFYDVDNFIEWCKKVRAYGIDVPIIPGIMPITTYNAFLRRAQWGEINIPKEFI
EQLDPIKENDELVREIGTKLIVKMCKKLLQSGYVTHLHIYTMNLEKAPLLILDQLGLLPT
EGEYNKAQVAMLPWRKSLNPKRKNEEVRPIFWQRRPYSYVARTSQWALDEFPNGRFGDSS
SPAFGDLDLCGSSLIRQSPKRSLEIWSTPTSLDEIAKLVINYLNGRVQCLPWSDTPIDHE
VDSMIKNLVQLNNKLIITINSQPQINGIRSNDPIHGWGPKDGYVYQKQYLEFLLPREKLP
KLEAELKDNEMLTYFAVDSKGTLTSNHPDGSRANAVTWGIFPGREVLQPTIVEKVSFLAW
KEEFYYILQEWELNFQENEKLESAHFLQHLIDDFVLVNIVDNDYVSKEDHIFALLMDL
>A0A539DCR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MSIAPRSLAEARALLLSPLGPVARAGQDLSRPNVSFEYFPPKSDEAEANLWKAVTRLAPL
APEFVSVTYGAGGSTRERTHRTVQRILAETAMTPAAHLTCVEASREEVDAVIEGYRDAGV
RHIVALRGDPPGGNGIGGAYVPRTDGYANATELTAAITAKGGFDVIVGCYPEGHPESPSL
DHDLDVLKAKVDAGATRAISQFFFDIDAFLRFRDRVRAAGISIPMSPGIMPVTNFNGLKR
MSAACGAAVPDWLAAHFDGLDDDPETRKLIAASVAAETCARLQEEGFADFHFYTLNRADL
VYAICRVLGVRETKGAAA
>A8UF07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium ALC-1|TrEMBL
MKVTEHIKKANGKTQFSFEILPPLKGQHIQSIFDNIDPLMEFKPPFIDVTYHREEYVFKE
VENGLLKKQVVKKRPGTVGICAAIQNKYGVDAIPHILCGGFTKEDTENFLIDLDFLGIEN
VMALRGDAVKSETYFKPEKEGHSYANELISQIAEMNNGKYLDEELQNSSATNFCIGAAAY
PEKHMEAPSLESDIHFLKKKIKSGATYIVTQMFFDNQKYFNFVDKCRKEGITVPIIPGLK
PISTKKQLNLIPHRFHVDLPEELIIDIVKCKDNKAVRQVGIEWCIEQSKELQKAGIPVLH
YYSMGKSTNIKAIAKEIF
>A0A1J5DB03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG2_30_43_15|TrEMBL
MKLREALAKRKFLVTTEIQAPIDEEPEGIVKTFNLVRGRVDGVSVSEVEIEGIVGDTIKT
CEVLKQNRFEAIYQTSTRQKNRLQLQKDLILAHEAGVENLLVFTEDYRITGDSLQEIMFF
HVDSGKLASVLEHIREGRTVDGKELPYKAEFILGSGVESCWGKNVPELEMKEMEEMTRIG
TGYFLTTPVFDLDRFEKFVKTVGTFGVPVIAEVMILRTAGMGRFLNRHFKSGLVPEWIIQ
KLAKASDKQKASIYLFADIVTGIKDICQGIHIITIGGEEKLRYYLDAAKLR
>A0A2E5AVD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MINSNLYKNTFKTSFEVVPPKYGINNIFLKKLVKYSNRFDLLDLTCCPMANLRITPISIA
HLLINQGVSSKKIIINFSTRDRNTLALQSEILGALAMKINKILVVKGDRIIKGNSKKSKE
VFEINTVKLIKILSDLREGYDYCKNRTNTSLNYEIFSTLNLNKSYKELKKIINQRLKQGS
NFFITQPIFSESDFELISKLSMKTDYKILCGILPITNTKVLNTVFKKLGGVNIDSQHLKK
IKNIDENEIFNYSKEYLKNLIKVYKSHMDGIHIMTSGDISKASKLIENI
>A0A3N9MWR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MTLKDKIESKQFIICGELGPPQSCNGDVIRKKTAHFKGYVDAVNITDNQTAIVRLSSIAS
AKILLEEDIEPIIQMTCRDRNRIAIQSDLLGAAALGIENVLCLTGDHQKFGNHPESKGVF
DLDSIQLVATLAKMNKGFLLSGDEMKTKPHFTIGAAANPFAEPFEMRLIRLYKKVMAGAY
FIQTQPVFDLEIFQRWMEKVREMGLHEKVTILAGVMPVKSVKALLHMLEEVPGVKIDKQY
INRMEQAADPQEEGIKIAVEMINALKSVEGVRGIHFMPVMWESITPVILKEAGLCK
>A0A7X2MAS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] rectale|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNQYNVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPERFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVKVAKRLTEGIKNLI
>A0A7Z7BZI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia sp. 509MF|TrEMBL
MSCTEARFSFELYPPRTERAAAALPGTIDLLAATRPDFISVTYGAGGSSRTASLDVLRYI
IEHTDVSPMAHLTCVGSSHEEAHRLIRDFLDAGVRRFLAVRGDPPEGLAEGDDGIGDIRT
TAELVQLIHRVQAERVPYGELAVPELHAQAVLEHREHVQIAVAAFPNGHPSSHSVSQDID
ALLAKQAAGANLGITQLFFHAEDYFHFTQRAAEAGVTFPILPGIMPVTSPARLKRMLELS
GEDLPSDLAIELEVEPTDEGRREIGIAWAARLGERLLAGGAPGLHLYTFNQHEAVLSVLD
RIGALPAASETASTTPANPATEKEPA
>A0A7G7YMX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium anserum|TrEMBL
MATIRRQVAVSESLKLTTPGRVPFSVEFMPPRDDAAEQRLWGAAEAFHDLGVSFVSVTYG
AGGSTRERTLRVAEQLATKPLTTLVHMTLVNHTVDEIKELIRNFASVGLTNLLALRGDPP
GDPNAEWIPTEGGLLYTSELIELVKSMPECEDFDIGIASFPEGHYRAADLEADTTYTLKK
LRAGAEYSITQMFFDIEHYLRLRDRLAAADPEYGTKPIIPGLMPITSLRGVRRQMELAGA
SLPASLEKRLLAAAAGDEVKNKAAIREVGIEVTTEMAERLIAEGAPDLHFMTMNNVRATQ
EVLHNLGMAPAWGPGYGHDMVR
>A0A8G0W3E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium scindens (strain JCM 10418 / VPI 12708)|TrEMBL
MKTTELFQNKSVLSFEVFPPKRTNPVDTIYKAIDSLKDLDPDFISVTYGAGGSEHCKATL
KIASRIKNEYGIESVAHLPCISLTKSDVRRQLSDFKEAGIENILALRGDVPSGGYVPGDF
RHASDLIAFIIEHGDFNVLAACYPEGHLESADIFDDIRNLKTKVDAGASHLITQLFFDNQ
YFYRFRERASLAGIQVPIEAGIMPVTNKKQIERMISLCGVTLPHKFSAMMERYEHNPDAM
RDAGIAYAIDQIVDLITHGVDGIHLYTMNNPYIAARIYEAIHQLLAA
>A0A5A9ZJR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia sp. ANT_WB102|TrEMBL
MTQLPDSDPTDGGRPPSIVERIATSTTPRVPFSVEFYPPRDEVAEERLWRAASVFSDLGA
AFVSVTYGAGGSTRDRTVRVVERLVRETDLLPIAHLTAVDHTVAELSDMIRMYGDVGVSN
ILALRGDPPGDPLGDWTAHPEGLHYAEELVRLIHEVGDFHVGVASFPEGHYRARDLDHDT
EILVNKLRAGAEYSITQMFWDVEHYLRLRDRAVAADPEQGAKPIIPGLMPVTSLRQVKRM
VELSGCALPDDLSERLRAAAGDGPEENRAAVREVGIDLTTRMCDRLIAEGVPCLHFNTLN
FSKATHEVLANLSMAPASGVAAGQI
>A0A7J3GDG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MVQAFSNLMRNILDGKFVYTGELEPHKSIDLSEVISWAKTLKETGRIVAANVTDNPKSVG
SISSLVASYIIQRETGLEIIYQLRCSDRNRLALVSDLLGAAALGIRNVLALTGDHPRQGD
MPTAMPVYDLDGTQLVDLIHRMVYEGKDIDGNEIHGPRPQFNIGAAANPNFKPLEVEVLK
IERKAEVGAEFFQTQVVFDVNVALEFLDAVKHVNAAFLIGIFPPRSYGQAEYFAKYVPGV
QVPAEFLDNLKKISEISDRKERRKRIDEYNIEYFSEFIRAVKKKPSCRGIHIMAVGYPEV
VGPL
>A0A7J3BEW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MMTRTAYSDLMKSIQSGRFAFTGELEPVKTTSLHEVLEGAKVLKDHVIAVNVTDNPTAFA
YMNALVPSYMIQKEVGLEAVYQMTVRDRNRLALISDVLAAGALGIRNILALTGDHVTVGD
NPQAKPVFDLDSATFVYMLRKMVDEGVDLGGNKIHEPPKFNVGIAANPNADPLEPEILKI
ERKVRLGADFVQTQAVYDVELAKRFMDAMSYLDIPVLIGIAPFKSLGMMEWMVKFVPGIV
VPEEIQIRLKQAKERGGKEAVYKENIEIFGNLIRSLRTSTKAAGIHIMAIGFEWIVPKII
ERSGVTSNIT
>A0A009LA46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 146457|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GQGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A2R4NXE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter concisus|TrEMBL
MLKEKILNKEKGLVLYGLTPPKAEFEEAKLREISERWSGRINDIKADGLVLYEVQDESER
NDNERTFEFSGTLSPEIYYKKYLNVATPSIFYRVASGYGEDDFRAALKAQSSNLNVLVGA
TSSTQKVRLNLARAYEIASEFKELAVGGVCIAERHGKKGDEPQRMREKIAAGAKFFISQA
IFDAQLAHKFLEDCAAAKISEPIFLTFSTAGNAKTLEFIKWLGVSVPSSVEERLNLSSDY
LASSCEIIKEIWCELKKFGDENGLNLSINIESVMAKRAEIEASLELTHKMREVLYSSE
>A0A0V9JAH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. 50677481|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A2N0BW70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira haakeii|TrEMBL
MKKILEIYKTAKTPVYSFEFFPPKTPEGEVKLFEAVGELSKVDPGYITVTYGAGGSTREK
TIRITSELAKKFSLPAAAHFTCVGGNKDEIRVILKQISESGIENLMALRGDPPKGEEAFK
KVEGGFGYASELISFIKEEGFDFCMGAACYPEKHPEATSLESDVDNLKRKVDSGASYLVS
QLFFKNSNFESFLNLIRKKGINVPVIPGIMPITSFAQIERFRSMAACEFPDKLVSDLEKV
KDQPEEFYKRSVDFSVNQCRELVKMGAPGIHLYTLNQSPASLDIVRELKN
>J0YUC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus infantis SPAR10|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFINEQAPHFDVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQS
>A0A420W9A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermovibrio guaymasensis|TrEMBL
MEFREKLESGQFLITVEVAPPRGVSWEETISALKPLKGKVDAFNVTDCQRSMVRMSALSM
AKLLLDSGYEPILQLTCRDRNRIALQSDLLGAWTLGIRNLCLMTGDFTTLGDQPDAKPVF
DVDSVQLIEIAEKLNSGRLLNGKELNGKTSFLIGAVHNPFAGPEFLQTLKLKKKIEAGAR
FVQTQPVYELKIAEEVHSLISSLGAVPLIGLLPIKSLKMANFMKRLNPTSIPPSLIDGLE
RAKDPVLYGWEYTLDLARAVSEFGAGVHFMLVGKVRELADFIDELRNNRREGP
>A0A291HKK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zobellella denitrificans|TrEMBL
MAFHSARHVEALNQSLAELNGDINVSFEFFPPNSEQMEQTLWHSIERLKTLAPKFVSVTY
GANSGTRDRTHKVIKDIQDKTGLVAAPHLTCIDASRDELRGIARDYWNNGIRQIVALRGD
LPQGMEKPDMYAADLVSLLKEEADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTIGIDVEIVPGILPVSNYQTLIKFAGFSNVKIPGWMHQRFQ
GLEDDQNTRNLVGASIAIDQVRVLSREGVKDFHFYTLNRSELTYAICHTLGVRPQAAK
>A0A4R9XKP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.216.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKSDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVIQEFAGMGVTRFVALRGDPAEGVGA
SYRPHPDGYANGAELVGAMKGAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A415W9H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium AM21-21|TrEMBL
MKISEILKNKSTISFEVFPPKNKEGNISSIYSTIEGLAKLSPDFISVTYGAGGSTKGKTV
EIASVIKHEYGIESVAHLSCISSTKEDIKYECERLKEAGIDNILALRGDYPADAADFDPE
NLEFHYASELNKFIGEHFKGQFCLSGACYPETHQEADGFKKDLEALKKKVDAGAEYLVTQ
IFFDNDYYYRLVREARKIGITVPILAGIMPITNAKSLIRTTKMCGCTIPYQLSTMIEAHY
DNPEAMKEIGINYAAQQIIDLITNGVDGIHIYTMNRAETAQRVFESIPAVLKELN
>A0A7W9BKK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loktanella ponticola|TrEMBL
MPQSTVWSIHPSLARKSLLNDYSLEIPVSKVSSFHPPPEIFVKGSEVYLPHLSQKDTAGL
KDACKKIVALGYQPVPHVGARHFADEAQLREHLTAARDGGARRLLVIAGDRDDSQGPYID
AMSVLSHAMVSDLGFAHVSVSGHPEGHSRINGDQLLDALEDKLEMLAVRGIQASITTQFG
FDAATYVRWINMLRERDIDTPINIGVAGVTSIPSLIKYAALCGVGPSLSALRKRSGAMVG
LLKGYEPTELVNELSQTLTLNDKAPVKLHFFPFGGARKTFDWITARSGTPK
>A0A8J6LU77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neobittarella massiliensis|TrEMBL
MNLSTLYEQKKCVLSFEVFPPKKTDDVRGLYRTLEGLHDLAPDYISVTYGAGGSGEQRQQ
TVHLADTIKREYGIEPLPHLTCINSTRETVLALLDELAALGIDNVLALRGDRVEGALPGA
FHYASELVELIKSRGGFSVAGACYPEGHTEAPSLEEDIVHLRRKVDAGVSHLASQLFFDN
AAFYSFEKKARAMGITVPIAAGIMPVTNKSQIERMVSLCGASLPDKLAGIIDKWGHNKAA
LRDAGIAYAVDQIVDLMASGVQGIHLYTMNSPYVAKKVVGSVQKLLCDLNCTEA
>A0A2W4K8Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MKGGDAVGERAFLERVRCEVLLGDGSPAALLNARPVGGIPELLNLHDRRQVEDLHIAFIR
AGARVIRTNTFSANPIRLRRHGLADRVWDLNVWGAKLARSAREVAGEPVFVAGVLGPLVP
VGAVDGNERDRQGEGARGLPPAAALPAAGGPGAAAGEGLLVAYRQQVEALLAGGVDLFLV
EAADDARQALAAVRAVRSTCHLPVAVVISFAASGRTPAGQTVEEALTLLQPKDLGPPDLF
GHGGDVDPQRSVELARSLRAAGWTGPLWVLASPVGVKEAFAGLVASLAALGPGVIAGSAG
VTPAHVAAAREVLASVGSPTPVRDEATRNHRLEPRPPSGDRLPVSTRVNGTVRIRPATGP
QPQAEVLEVPRHGAGAANLVAASSVPGGPVAPVPARPVPGAPAPGGTGAPEPTLREKLGG
QFVVSVELDPPRGTVVHKFLDDARRLGEAGADCINVGDSPMARVRMAAIGGAYLIQAAIG
LETIVHFTTRDRNLMALQADLLAAHALGLRNILALTGDNPRLGNTTASAVYDVDSIGLLR
ILRELNRGRDITGNSIGEPTAFTVACALSPNAENLDRELDRFRRKLEAGVDFVMTQPLYE
TAPLERVLDRLGGCPVPIVMGVMPLHSARHAHYLHHEVPGISIPAHVRGALEKAGDRGLE
VGLELAEAVVEAARPWIAGVYVVVSFGKVEPIAAFVRRLKARFVGGTPEGRSGRGGAAPA
RPARGDPR
>A0A7C2E0I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MEFLERLARGPLLADGAMGTMLYARGVPFDQCFDALNAEQPGLVRAIHREYVEAGAELLE
TNTFGANRFKLAAHGLEGRVRELNVAGARLAREVAAAAGRRVWVAGSIGPIGRPLAPLGA
VTPEEVGEAFAEQAAALAEGGVDLLLFETFTDLAELAAGVAAARAATALPIVAQMTFTHE
GRTLLGHTPADIVARLEPLGVAALGANCSVGAQGILQVMEQLVLLTRLPLSAMPNAGFPS
YVGGRVIYASTPAYMADYARQLVELGVAIVGGCCGTTPQHIRAMGEAIATVAWRRPPRLT
VAPAAAPQPAAPPPPPTTLAERLRRGFVVTVEVAPPRGTQEGPELGTCRLLRQAGVDAVN
VPDNPMARLRMSPWGMALRIEQEVGLPTILHFTTRDRNLMRVQSDLLALHALGIRHLLVL
RGDPPQLGDYPTATAVSDVTPTGLIRLVKQFNQGRDLPGNDLGQPTAFVVGAALNMGARR
LDRELRVLEQKLAAGCDFLCTMPLFDPETLDRFLARVGRLPVPVIAGVLPLHSARHAEFL
HNEVPGMVVPEAVRERLRAAGGDAREVGLQLAFDLIAAIRSRVQGVYLIPAFGRYDRVIR
LAEAVRAAAGERAGPARDGSAGGAGFVGDPHEAGGGAGIVGGPHEAGGGGAAGGRR
>A0A7C6J461|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MVATRINKELIELVTPKQSTTDLEGEMEEFAERYQLFLENTMAICIPDNPMSNISYMGTE
MIEALELPVEPESFVLHLNTFHRKTDEKYDPAKDQNEQDFDILVEHAAALGIKYLLCVSG
DGSERLPRLQPEDLGYDPEKTKTVTSVQLLEYLGRAYPGVFTLGTAFNQYEPLEAEMEKL
RQKIAAGAVFIITQPVVLIESGDPALTTANNNLHQMMKYADDQGVQVILGAWMSVKLAYL
IPECIGFEVDFGNFSPDENLKVIRETYPERRLYYSMIFTAKRLQKVLAITEGK
>A0A4Y8PBB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylacidiphilum sp. Yel|TrEMBL
MATLIDRLNESLLIGDGALGTYLYSLGIPRGYCIEELSLSHPDLLEKVHRDYIDAGAKII
RTNTAEANAYHLSFFKLEKKLKEIVSRSVQLAKKALGSREGWIAGTVGPIWTKPTESPID
MAKRQSLYEELVASLMEEGVDLLFFETFTELSELLLVLDIARKKGADKLFAFIASFEEGK
LSSGETLGEAFSKLRLAGATLVGINGACGVQASIHLLEEIELKVGDFLGAYPNAGKPEFY
DGTFTYSASPSYFGENVERFAEEGVCLLGGDYGTEPAHIAAMAQRAATIKPLKEKPPKRR
PRYQLSEQEILPQIEPSLLELLALKPVFMVEYDSPKTLAIGKFLEGVKAIEKAGADAITL
ADNSLAILRISNFAAAIHVRRVSKMIPILHIACRDRNLLGLQSELMGLGTLGFRHILALT
GDPAKSGDHPGATSVYDLNSVGLIRLLASLNRGFNAAGKDLKGKTDFIIGCAFNPNTSQF
EAQVKKLEAKLAAGAQFVMTQPIFDIQLIKKTYNYLKPLGIPVFIGLMPLLNYRNAEFLH
NEVPGISIPEAVREKLKALDGEKATEVGVGFAQVLGEEILSLFKGIYLITPFLRYDISVR
LLELLSSRKKS
>A0A7C1I8V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MKNLKIKDIIEQKSFVFSLEIFPPKPDSDISVIYDTLNKMKELKPDFISVTYGAGGGTRE
RTVQLADKIENTYGLTSMAHLTCVGATKESIGDILDELESCGVENIMALRGDLPEGGREN
LKDFKYASDLVDFIKKGRWKFCVGVAGYPEKHPEAESLEKDIENLKKKTDAGADFITTQL
FLDNGYFFRYVEAVKKAGIKVPVLPGIMTATNPVNVERMAAMCGVEIPERFREAASKCRI
EDAVCEETVDYTVAQINHLIKKGVKGIHLYTMNKAEQNRRIYENSDIRKARK
>A0A1N7LUV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeovulum vinaykumarii|TrEMBL
MSRPRVSFEFFPPQTLDASFRLWETVRALAPIGPEFVSVTYGAGGTTRQLTHEAVTTIGK
NYGLDVAAHLTCVEATRAETMEIVNAYAEAGVTQIVALRGDPPKGHGAFTPHPEGFASSI
ELIGALARDGRFTIRCGAYPEPHPEARDASADVEWLKRKIDAGASSAITQFFFEAETFLR
FRDACADAGIHAPIIPGILPIQSWAGTKRFAERCGTSVPGWVEAAFETAIRDGREETLAL
AMCTELCDRLLGEGVEDLHFYTLNRPGMTLDVCAALGLAAPGALEAVA
>A0A1A9FZV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp. (strain HZN7)|TrEMBL
MAHIDENPLGPHLPLDPLPGHSSLGRLERVLRRGEFAVTTELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGV
GPMASAKTAKWIRSNVPGIHIPDSVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEIVHDSGVLKGRQPWKREPNPVDQLVAERIERTRQGVEQNQQQMAETAA
HHPH
>A0A653W7P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. 9I|TrEMBL
METPNFSIEFFPPKTDEGAEKLRAVRQKLAELQPKYFSVTFGAGGTTQQGTLQTVLEIKA
EGHQAAPHLSCVGGSRESLRAILQQFQDNGIRRVVALRGDLPSGYGAGGEFRYANELVEF
IRKETGDWFHIEVAAYPEMHPQARSPQDDLQAFARKVQAGANAAITQYFYNADAYFDFVD
NARKLGVDVPVVAGIMPITNYTQLMRFSDMCGAEIPRWVRNKLASFGDDSASIKAFGLDV
VTSLCERLLAGGAPGLHFYSMNQAAATTAIWQRLVK
>A0A3B8KDA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MTKSNLQKVLESGAFAVTGELGPPKSGQRDVIEHHASHLKGVVDSVNITDNQTAIVRTSS
IATGRILLDMGIEPNVQMTVRDRNRIAIQADVLGAVALGMKNILCIQGDHATLGNEPKAK
NVNDLDSMNLISALKKMRDEQEFIGGDKLDAPIDLYIGAVANPFADPFEYRPYRLAKKIE
AGAQFIQTQVIFDMERFERYMKIVVDMGLHEKAHIIAGITPLKSLGAARYMKNNVAGMIV
PDHIIDRLKGAKDKKAEGVNIAVEMIEHLKTIEGVAGVHIMAVAWEEIVPEIAERAGLLP
RPTFD
>A0A2V1E714|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Periconia macrospinosa|TrEMBL
MHISQMLAQSRAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHDFGPKFIDVTWGAGGSLS
HLTCEMIKVAQNVYGLETCMHLTCTDMEKSKLDNALKEAHDAGCSNILALRGDPPREKEK
WEAASGGFRYAKDLVKYIRERYGNYFDIGVAGYSEGCDDNDDVDQLIDHLKEKVDAGATF
IVTQMFYDTDLFLEWVGKVRAKGITIPIIPGIMPIHTHAAFLRRANWTRCNIPQQWTEAL
EPVKNDDVEVREVGKGLVAEMCRKLIDAGILHLHFYTMNLAQATRMVLEELELLPDVESP
LQKPLPWRPSLGLNRREENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDARSPAFGELDA
YGVGLKGTNEQNIKLWGSPKSIKDISDLFVSYMSGKLSSLPWSESPISTEADTLRKDLIN
LNQRGFFTINSQPAVNGAKSSDPVHGWGPRNGYVYQKAYLEILVSPEHIAEIITRVERNP
NLTYYAVNKDGDLKTNSSGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFFKVGKEW
ANCHASTSPSRYIIEDLMDTWYLINIVHNDFHVQHGIFPVFDGLKVADMEKQLYETGTSN
GHATNGSNGNDAPAAKASKSTLNDLVEAAKSAADTVTTGITGVKVSS
>A0A4V2AR47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcaceae bacterium|TrEMBL
MKIRNCLNPSQPCFSFEFFPPKTDAGVASLLRTVEELAP
>A0A3N2CP21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmoricola aurantiacus|TrEMBL
MSTMKIPTGVRRSQRGPRAQRATREQAMRRLLEHTRYEVLPTATTEDKVLAAVPTDVAVT
VTASPGKGLEATLTLSETLAGHGYAVVPHLAARMVRDHAELVDIRARLRAAGISAVFVPG
GDAEPAGDYTDAFSLLEDLATLADPFTHVGIAGYPESHPTIADDLTVQAMWDKRRHATHV
VSNLTFDAATIRDWVGRMRLRGITMPLLLGMPGPIDRAKLLTMATKIGVGESTRFLAKHK
GTFARLAAPGGFTGERFLRDCATVAAQPTAGIEGLHVFTFNQVAETEAWRQGLLSELP
>A0A5N8WEZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces phyllanthi|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATEQIASDTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPDGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSERWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDSVAAAGCETPVIPEVMPVTSVKMLERLPQLSNASF
PPALKERIVTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPAQA
>A0A180F6T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium Barb6XT|TrEMBL
MKVIDLISSGKQPAFSFEILPPLKGNTIKNVYSVVDKLQEFAPRYINITSHHSEHQYKTL
PDGSFQKVSIRKRPGSVAIASAIQNKYHIPAIPHIICKGFTKEETEYAMIDLNFLGVHDL
LLLRGDNKSQETQPSPDLYHSHATDLQQQVNNFNRGIALDGSTFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNAKYYAFVERCRAEGITVPIIPGIKPV
VFKNQLTVLPRIFRSDIPEPFAAELRKCKDDEAAKAAGIEWCVSQCKDLAAHGVPGLHFY
TFMASDSVYKVAKEVY
>A0A7W6XZ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium esperanzae|TrEMBL
MAMSQAIHLRDQSDVLDDFSVEVTTKDTAQLAAMSGAIPKGTIISIPFLSTESDADRIRA
AKMVRQAGYVPLPHIAARRLESESMLSAMLSALVNDAQVSRLLLVAGDADPPKGPFLDTA
TILRSGILEQHGISNVSIAGHPEGHPVQNAAMLTSALLEKRLIMEAANIEWSIFTQFAFA
SEPVLAWIGELRRLGIEVPIHIGIPGPASVRTLLKFAAVCGVSASTSVLKKYGLSITQLL
SSAGPDALVNEYATGLSNAEYGDVRLHFYPFGGLHKTVDWLQEYRTRPS
>A0A7Y8IC11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MKSGSNLEKILEAGHFAFTGELGPPQGANVEAVRKKAGYLKGIVDAVNITDNQTAVVRMS
SWAAGLIAIQEGLEPNFQMVCRDRNRIAMQSDILGAYAHGIRNMLCLSGDHQQFGNHPLT
KGVFDIDSIQLISMVKQMRDEKKFLNGDEIDGPPQIFIGAAENPFAEPLEWRVHRLAKKV
SAGADFIQTQCIYDMKIFREWMKQANDMGLTEKVHILAGITPLKSGGMARYMAKNVSGII
IPDEIIDRVVKAKKPAEEGIKICVEQIEELKEMKGVHGVHLMAIEWEHRVPEIAERAKML
PRPKV
>A0A7W4TVI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. RAS22|TrEMBL
MHTLPDISATSVIPASIEASPAQVFGPASLAGLFPQGVRVYLTDTGAASQVKLVDAAKHL
RDLGYQPVPHLAARRIASRIDFEEQVKRLAGDAGVTDVLAVGGGVEKPEGPFTSTIDMLS
TGIFDRCGIRHIAIAGHPEGSPDFNDETATAALRLKRDFGERTAAAMRIVTQFGFDSARF
IAWAEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTTLARGHS
PESIVGPIERHWRDNPQGPIRQIHVFPFGGLQASSDWLVSRGSWRTENADHAAATGSVAI
>A0A2E5BB57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudozobellia sp|TrEMBL
MKITDHIKNAKGETLFSFEIVPPVKGRNIQELYNNIDPLMEFKPPFIDVTTSREEFVYRE
KDGLLEKQVTRMRPGTVGICASLQHKYGVDTVPHVLCGGFTKEETEYLLVDCQYLGIENL
MALRGDARKDQQYFEATKGGHAYATDLVGQIKDLNSGKYLHDDCQMDHLPDFCIGVAGYP
EKHLEAPSLKSDLKRLKEKVDAGAHYVVTQMFFDNQKYFEFVEAAKAMGINVPIIPGIKP
IAVKRHLQVLPQVFRIDLPQDLIDAVDDCATNKDVRQVGIEWDIQQSKELKEAGVPVLHY
YSMGKSDNIKAIAKELF
>A0A2A5AP96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Cloacimonetes bacterium|TrEMBL
MKIGPFVQADILPQKLNQKKFLLTLEVDPPKGPGVKKILSQIKPLIQYIDAINVACCPVA
KLRMDPLAFAILLKQEFDIEVIIHLTMRDMSLLGLQSYLIGSSALGIHNILAMTGDTARH
SDIPKTKGVFQANSLTLLKMMGQMNNRLNFDGKKLNKKSKFFAGATCNPSAINLTNEIKK
MNKKIEAGAEFFQTQPLFLDKNLDVFLKYTNTEIHKPILMGTMLLKSYDSSLWLNESVPS
LFVPSEVLTSLKKDDTQENGLKIASEFCKKAMNKVNGLHLFPLNNYEALLELVQEVKSFQ
KK
>A0A3R6TV73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM27-28|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPDLCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A359K9R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp|TrEMBL
PGYLPKMFEGLDDDDQTTRTLLGANIAMDMVKVLAKEGVKHFHFYTLNRSELSYAICHML
GVRANGN
>A0A653W8X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 8Z|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARELASYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDTKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGDHFHIEVAAYPEMHPQARNFESDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRKFGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSDSIRAFG
EQVISEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLPR
>A0A4Y3M782|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter roseus NBRC 3990|TrEMBL
MERRLWACIRRLAPLSPRFVSVTHGAGGSTRNSTQASVLRLQQKTNLVPAAHLTCMGASR
EEVDDIARQYWEAGIRHIVALRGDPPAGGAGYTPHPDGYAYASDLVAGLRRIADFEISVA
AYPEGHPAALSPEADLDNLKRKLDAGATRAITQYFFEASTYLRFLDRCLAAGITAPIIPG
IMPVSDYDQIAQFSKMCGITVPSWLTHLFEETSGNPELRRTIGSLVAVEQIRALQARGVN
EFHVSTLNRPDLSYAIAHILGARPTGSLKQADSSGQQDKTDD
>A0A8I3ASW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium longisporum|TrEMBL
MDKITDKIAALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
AFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPPRKAE
YQDAVDEESDDDEDFVWATDLVKYIRKNHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVEKTQAGADFIMTQLFFDIDAYDHFEQVLREHPSGAFKTIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDALMARLDAVKGDDEKVKEVGVDIVSELVDQIRAVKSKRTTGPQGFHFYTL
NLEKAVSFILERTNLIPDKEQEDEEAVIDDATTPPVVPTVQINGLHPGSHHRPGRRQSSI
GSDPHNRVIVSSASNHAYETNPEGAGLPAEPINTRANTLAISEGEGVLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVTQAVRLWGHPKSSEDISTLFIKHIRGELSAIPWSEE
GLSPETNIIQEQLIELNTRGWWTVASQPAVNGVPSRDATFGWGPSHGFVFQKAFVELFLP
AADWKVLSERLTGPEVEGTVCFYACNGNGDFATSDDSGGLVRTAVPASTNAVTWGVFPGK
EIITPTIIEEVSFRAWSEEAFKIWGEWSRVYGRGHESEKFLQSVKDEYWLVNIIHHDFVE
TNALWDLLRG
>A0A1N7ID61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium shigense|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTPGGHASAMDLVHQINDLGRGKYLHNDEKACDELNKFCVGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVTKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEELINEVEKAKNNEAVKQIGIEWAITQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A7X4IK23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0675_bin_23|TrEMBL
MTPRTLQHTLVQGQFAVTVELNPPKGTDVSELLETAKSLSGRVHGINVPDNAAAVLRASP
VAVARLLYEQGHDPVLQVTCRDRNRLALQSDLLGAHVLGIRNVLCLTGDSPGTGDHKDAK
PVFDLDTVQLMHAVQELNEGRDLAGNALEGRTAFFIGGAAAPGAEPAELLHKKFEAKVNA
GAEFFQTQPVFSAKVIHPFMEAVRPYSRKVLAGVLVLRSVKMAEYVNARVPGIDVPDEIL
QELRNAGDARVSEAGLEIAVRTIRAVRPFCDGVHLMAGRLAHRLPEIIRKAELS
>A0A2M8FXS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_9_14_0_2_um_filter_42_21|TrEMBL
MCTFGGTEKNKSFLTTQRENERLSSTMNFLEKLQHGILADGAIGTELYKSGVFVNRCYDS
LNLQEPARIKAIHQVYFDAGARLIETNTFTANRLALAEHGLEDDLEAINAAGVRLAKEVV
GEQGFVAGAMGPISWFQKQGGDARASKAIFVEQVSALSKAGADVILLETFLSLDELALAL
EATKSVTSLPVMCQVSLKFTSDEEFEGLQPEKVVSFLEERGADVIGVNCSDGPIGIFEAL
KRMSAVSNTPLSAMPNAGMPKMVQGRMLYMVTPEYIAEYARRYAQLGVKLIGGCCGTTPE
HIREMARFLKGVWTESAREIPSSQKESKSIVSEKNEARPAIATAEKSPFGAKIGKEFLIS
VEIEPPASIHPDKAVEGARILKEMGVNAVNISDGPRAMARMSAVSLSMILKEQVGIETIT
HYCCRDRNLLGMQMDLMGQAALGLKNLMLITGDPPKMGHYPDATPVFDLDAIGLIRGVSH
LNQGLDFSGRPMKDQTSFLIGCGVNPGAVDLDLEAERYRRKVEAGAEFVFSQPVYDIKLL
ETFLGKIKNVKPIPFFVGVLPLASLRNAEFLHNEVPGMQIPNEIMKAMQAASTKEAQREV
GLEIARDALVAAKSISFVRGAYVFPPFRSYQAVEKLIEVIR
>A0A653MA20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 8O|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRVFG
EQVISEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLPR
>H8KWP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solitalea canadensis (strain ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB 12057 / USAM 9D)|TrEMBL
MKITEHIQNAKRPLFSFELLPPMKGQSIDQIFEAIEPLMEFEPPFIDVTYHREDFIYKKQ
PNGLLEKVSTRKRPGTVSICAAIQFKYKVDAVPHLICGGFTKEDTENALIELKFLGIDNV
LVLRGDARKEDGGFIPEAGGHSYASELLEQVVNMNRGKYLHDEYNGINGTNFCIGIAGYP
EKHFEAPNLKTDIRYLKMKVEMGAEYIVTQMFYDNEKYASFVKTCRDNRINVPIIPGLKP
LTTKKQLTLLPKVFNIDIPEDLADAVMDCKTDKEVREVGIEWCIQQSKGLIDLGAPCLHY
YTMGKSETIKRIAKAAF
>A0A4R1XG05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PP-F2F-G48|TrEMBL
MYTRTLYPAERGDLRLSFEYFPPKSDEMDAQLTRTAAALNAYAPEFASVTYGAGGSTKAR
SLTTVRRLIDDCAIPNTAAHLTCVGATRAEVDAVVDEFAAAGVRHFVALRGDPQGGIGAR
YQPFPDGYENAAALVEALARRGRFQISVSAYPEKHPESSDVDADIDMLKRKVDNGATRAL
TQFFFDNNDFERYLERVRKAGITIPVVPGILPINQFSQVSKFAGLCGARIPEALALRLAH
LDESPEERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFKRLDDIAEG
AAA
>X6E9D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNHC220B00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLHPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHQVDAVIQEFTDMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDLQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEVAGS
AAA
>A0A2E2QZR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sutterellaceae bacterium|TrEMBL
MLRPTTNSVNEYTMMNISFEFFPAKTDEGAEKLRATREKLSERKPEFFSVTFGAGGTTQD
GTLSTVLEIKAAGEEAAPHLSCVGSSKEKVAALLKQYKEHGIKRIVALRGDLPSGMLETG
SFRYASELVEFIRRETGDHFFIEVAAYPETHPQAKSPAADVDAFVHKVNCGANSAITQYF
FNLDAFLYFRDQVQHRISIPLIPGIMPVTNFSQLARFSDACGAEIPRWMRNRLQHFGDDR
ESIRAFGLEVVSNLCEQLIREGAPGLHFYTMNNAQPTLAILDQIGY
>A0A2M7ZAV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriales bacterium CG_4_9_14_3_um_filter_34_10|TrEMBL
MKVIEHLAKAKNTLISFEIIPPKRGGDIKQLMNVLDDIIKYNPPFIDITSHSAEVIYEED
SHGEFKVRVKRKRPGTLGICALIQHKYNADAVPHVICNGFTKEETEDFLIELHYLGIDNL
LAIRGDDNGYKKPIKFGRSVNTYAVDLIEQIDGMNKGKYLEDSLLDAKPMNFCIGTSGYP
EKHFESPNLLTDIKFTKQKVEAGADYIVTQMFFDNSKYFNYLDLCRSNGINVPIIPGLKI
LTSKENLSSIPKNFYIDIPNELADEIAEAKPEHVVDVSVEWTLKQVEGLLNKNVPAIHFY
IMQNSKPINKLMKRLKL
>A0A5N5X5Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus leporis|TrEMBL
MLPFPLIGGPIKLRPKPFHPRWLSPQSSFFNHHLLRNFTGTVSVDKMERITDKIAALPPD
ANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGSTAQRSLELAEICQRQ
LQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNKDFS
FAVDLVRYIRQKYGDYFCLGVAAYPEGHPVDSFQDSQDPKRDIPYLVEKTQAGADFIMTQ
LTYDIEAYTNFENMLRNHESGSFKTIPIIPGLMPIHSYKILTRVTKLSHVKIPPQILSKL
EEVKHDDDSVKRLGVDIISNIVDGIRDIPYPGLRGFHFYTLNLEKTVSFILERCDLIPPY
TEYDAVEDGEDISAMDGAQLRSITRRRASSINSLPHNRVIVDKLQVSGASSKDSVSFEAP
ATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHV
SPSVAHRIWGYPVSREDISTLFRRHVSGDLHMVPWSEGGAEEGSPGLNAETEVIRPQLLQ
LIDGHGWWTLASQPAVNGVRSDDPTFGWGPPREGFVFQKPFVEFFCPNKDYQSVVKPLLQ
RHGHEKLAWFATNVKGDFESSMPAQTSDADPIEINPDNVNSVTWGVFRGKEIVTPTIIEE
VSFRAWGEEAYRIWDEWRRIYPRNSATERFLDETKNDVWLVCVVGQDFGAGTESAEEEEE
EKQWMWKVLLNAK
>A0A7Y4WNX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MAGCGACNPQTQNGGGSLMSLAVSFEFFPPRTDDMDAQLWRSIGRLAPLNPAFVSVTYGA
GGSTRERTHATIKRMLAETQLKPAAHLTCVGSSRESIDEIVRDYLRSGVRHIVALRGDMP
EPGPYAQVSDGYESTPDLIRGIRKIWPFEISVSAYPERHPDSPSAEHDYALLRAKIDAGA
TRAITQFVYDTDVVLRFADRAYREGVRVPIVPGIMPATNFKGVVRMAKRCGASIPDSLAR
KFEGLDNDLETRKLIAATVAAEQVEKLRRHGFDSFHFYTLNQADLTFAICHLLGVRAEAP
AAGS
>A0A2N3BZ91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HGW-Alphaproteobacteria-3|TrEMBL
MAKTQKKDVNERTRVSFEFFPPKTPEMEETLWTSIRRLEPLQPEFVSVTYGAGGSTRERT
HATVKRIHDETSLEPVAHLTCVGASRAEIDDVIRGYWDAGIRHIVALRGDMPELGAPYRP
HPEGYQSTPELVEGIRKIADFDVIVSAYPEKHPESVSIEADIELLKRKVGAGATRAITQF
VFDTDRHVRFLEKARAASVEVPIVPGIMPTTNFKGTKRMAGRCGASIPKWLDDYYIGLDD
DLPTRKLIAAYVAAEQVNRLRGYGFDRFHFYTLNQADLTFAICHVLGLRPQPVPAEPEAA
>A0A256G5C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella thiophenivorans|TrEMBL
MGFYGLSRRSDIGQTTRVSFEFFPPKSEEMEQRLWETVTRLAPLKPEFVSVTYGAGGSTR
ERTIRTVARILKETDIQPAAHLTCVDATREEVDHVAQEFAALGVNRFVALRGDPASGIGE
KYVPTQGGYQNGADLVGGLRKLSDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGILPVHNFKQVSNFCARSATHIPAWLAERFD
GLENDAQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPYAICHMIGIRSKTEASL
QVA
>A0A2R4N0A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carboxydocella thermautotrophica|TrEMBL
MDFRRKLLSGQFITTVELCPPRGIDCSKLLTTAKKIWGKVDAINITDNQRASIKISPVAV
CAILLKEGITPICQLTCRDRNRMALQSEILGAAALGVEYFLFMTGDHTLIGEDPKSKSVF
DLDSVQLMATAAQLNNGYTLNGKVLTGKPNLIYGGVVNPSLQCREAQMWKLERKVAAGIR
FVQTQAVYSVREVADFIEDAKRFNIRFLVGIIPLKSAAMARYMNKNIPGIKVPEKFIDIL
EKSKNPIKEGLRIAQDTINELKSISDGVHIMPMGTEEYLEELV
>B8MDD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MEKITEKIAALPPGSNYFSLEFFPPKTQMGSVNLQARLERMAQVLRPLFVTVTWGAGGTT
AAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIKNILALRGDPPRSEE
YNMDGDDDSNKDFTWAIDLVRYIRRTYGDYFCVGVAAYPEGHPGESQTDIQDPEKDLPYL
VEKVQAGADFIMTQLTYDFETYQKFEERLRNHPSGAIKSIPIIPGLMPIHGYKILTRVTK
LSGAHIPPAIMSRIEQVRSDDERVKQVGVDIVSEIVNQIKSLPNPGHRGYHFYTLNLEKS
VTLILERCDLIPPSSDDDAVEDDIAIEEVAVSNNKDDLKTLVSRRRASSVNSGPYNRVIV
DKLHVPTDQQSEHSSRKSITYETLASSAGVPALNPPPRSTQLQISEGIGSLGREATWDDF
PNGRWGDSRSPAFGEIDGYGPSLHVNATVAKQLWGFPVTREDIGALFRKHVSGELYIVPW
SEGGAAEDANLNAETETIKPQLLQIIEKKNWWTLASQPAVNGVRSDHPVFGWGPPGEGFV
FQKAFVEFFCPSSDYQNKVKPTLLKHGSEEFSWFAINAAGHLESSFLISTSSSPKPEDTS
SAVAAADEEPLEIRESTGMAVTWGAFRGREITTPTIIEEVSFRAWGEEAFRIWDEWRRIY
PRGSATERLLNETKNDVWLLCVIGHRYGAGTVPGSEEEKKEMNTLWNVLAGDM
>A0A3N5Z1H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MNQGNFLEEVSEGAKFDFCIGVAGYPEKHFEAPNLKLDVLNLKRKIDAGADYVVTQMFFD
NKNYFDFVKLCRESGITIPIIPGIKVLKNTTQLVTIPKNFYIDLPDQLVDAVTKDPKHVS
AIGKEWASKQVEDLLNKGAPCVHFYIMNDTGTIVDIVKKFQK
>A0A5P9J7X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribius sp. THAF1|TrEMBL
MTRISYEFFPPKSLQASFKLWDTIHTLAATAPDFVSVTYGAGGTTRKLTHEAVTTINKET
GLRVAAHLTCVDASKAETMEIAESYAAAGITDIVALRGDMPGGGAFVPHAEGFASSVELI
EALAADGRFNIRVGAYPDRHPEAASDDADVEFLKRKIDAGATEALTQFFFEAETFLRFRD
RCAAAGIDAPIVPGILPIENWKGVKKFATGCGTTIPAWLEEAFTAAERDGRADLLATALC
TEMCTELLENGVEQLHFYTLNKPHLTRDVVHAMGLAPEPALEKVA
>A0A537MDH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSPLATALSQPARPLFEDAAGDIEVSFEFFPPKTEKMEQVLWESVKTLEPLAPRFVSVTY
GAGGSTRERTHNTVARIQRETSLQAAAHLTCVEASRGEIDDVARAYWDAGIRHIVALRGD
PPEAGKPFSPHPQGYANAAELVAGLKKVAPFEISVAAYPECHPDSPTQVADLDNLKRKID
AGADRGISQFFFSPDCFLRFRDQVAAAGISAEMTPGILPVSNVAQTRKFAAMCGASIPAW
LDRLFEGLDDLPAARQLVAATVAAELCAQLYRGGVRQFHFYTLNRAELSYAICHLLGLRP
KEESHEHRRTA
>A0A099EYQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sphaerophysae|TrEMBL
MPTRSVPAVSFEFFPPRTLDQSFKLWETARALAPLAPDFVSVTYGAGGTTRQLTHEAVTA
LASHYGLNVAAHLTCVEATRDETMQIVDDYAAAGVREIVALRGDAPQGAAAWAAHEDGFA
SSVELIEAIARRGGFTIRCGAYPEPHPDSADTAADVAFLKRKVDAGATSAITQFFFDADT
FFRFRDACVAAGVDAPVIPGILPIQSWTGAKRFAARCGTSVPQWAEDAFVRAGKDGERAL
ARDMAIDLSARLIAGGVDRLHFYTLNRPELTADVCAALGVAAAEHAA
>A0A3B8QWJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium|TrEMBL
MESVASFLASEHPTAFSFEILPPLRGRSIDSTYSDIERLMEFNPAYINITTHRTEVSYRH
LGGDTYKVVTSTKRPGTVAIAAVIRERFGVRPVPHLICGEYSRGEIEDQLIDLSYLGITD
LLVLRGDRERNAPTFTTSPDGHEHAITLAAQVEDFNRGILADGTHTVPIAPPFSFGVAGY
PEKHEEAMNLTSDIRNLKAKVDAGASYVVTQMFFDNRRFFSFVEAARAQGITVPIVPGLK
PLTSLRQISMLPRVFHIDFPEELSDMLLGCTTDEDVRRVGIEWAIRQGAELRDAGVPSIH
FYSMHAVNSVAAVAREIY
>A0A3D5ZI21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
LRGDMPDMARPFKPHGDGFSSSLDLMAHLASHGAEEIYGGAYPEGHPESPSQSAELDHLK
AKQDAGATALITQYFFEVDCFLRFRDRAESHGITLPIIPGILPVANFEKAKGFSKRCGAS
IPQFVHDRFAGLHNNPHESALMGASLTAELVMELADEGVEHFHFYTLNRADLSLTACRML
GVRPT
>A0A2E3ZTZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTLNKKKISVSFEFFPPKNQLSIDSLWNNIKRLEPLNPKFISVTYGAGGSTRENTHNLVK
EIKKKTSLEPAAHLTCIGTSFDEIERIADDYWHTGVRHLVALRGDKPIDNDKNKNNDFKY
ATDLIKFLKKKHDFEITVSAYPETHPDSKSLEQEYDVLKKKIDLGATKAITQFFFDVNAY
FDFVDGALKRGIKIPIVPGILPVTNCKRTIEFAKKMNCKMPEDLTEMFKGLDKDQETRKL
VAVTIVYDQCKKLINGGVNDFHFYTLNRADLSFAICHILGIRTLG
>A0A359E6A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneolaceae bacterium|TrEMBL
MKVTEHIEKANGDTLFSFEVLPPLKGQNIRSLFDHMDPLMEFNPPFVDVTYHREEFVYKK
RDNGLLERKTVRKRPGTVGICAAIQNHYKVDAVPHIICGGFSREDTENALIDLNFLGIDN
VLLIQGDTRKPEREFKPEPDGHAYASDLIEQVVDLNNGIYIDEDLENAKPSDFCIGVAGY
PEKHYAAPNMQTDMKYLKLKQDKGGHYIVTQMFFDNQCYLDFVKQCREAGITLPIIPGLK
PITSQKQLTILPQLFHVDLPMELSKAVEECNSKEEVVQVGIEWTIQQSKELMEFGVPSLH
YYSMGKSASVYEVAKELF
>A0A534LDI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MPAEVTSRPIRAGTRLERILAAGSFAVTAEIAPPASADGSEIRRHAAVYRGTVDACNVTD
GQRALVRISSMAAATIALQEGVEPIMQMVSRDRNRIGLQSDLLGASALGIHNVLCLWGDP
PTAGNEKDAKAVFDLNTEEMIATFRGLRDAGTLRGGDKVEQAPKVFIGAAADPFRGSKEE
SFGKLRGKVTAGADFVQTQGVYDVDAFEEWMRLVRKEWLHENVYILAGVIPLKSAKMAQF
MVEKLGAVVPKHILDRMERAPNPKAEGVSIAVRTIKALKKIEGVRGVHLMPIGWEEVVPE
VVKQAGLLPRPDPKA
>A0A6H2F3I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae endosymbiont of Plateumaris consimilis|TrEMBL
MWNYNMKYFNTEKKEYIDKFFNKSFSKCNISFEIFPPSDCKIESKFWILIQTLIKFKPKF
ISITYRNINNSYNNKTYNIVKKIQKYTNIELAPHITCINLKNNELYNLAKKYWKNGIKHV
IALRGDKTKFNNNINSLIYASDLVYFLKKIANFNITVAAYPEIHPESKNIKEDLVNLKRK
IDAGATRAITQFFFNIETYLTFRDKCISQGINIEIIPGILPITNFIQLKKIIKITNIKIP
DFINNMFQNLNGQDEKICKLLGSFIAIEMIRRLKNEGVNHFHFYTLNKLEIVYAICLYLG
IKPNENILTNKT
>A7MNG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter sakazakii (strain ATCC BAA-894)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRSIARDYWNNGIRHIVALRGD
LPAGSGKPEMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPALELKT
A
>B0KGX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida (strain GB-1)|TrEMBL
MSLLKTALREKNFVCVMEFVPKPSAERFAAMEAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFANPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGLRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFFTLQLGF
DAAKHQEAMLWMRRQPTPKPMLACLMSLTHGRATMLDHVAGVTVTPSMRDMLEAETALSK
VFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQTRVHTLEQWAPA
WQASWQMPGLPAVIFHPPQASWRQGESQVDATFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPLWATRLGALVLHKVERAVKRPLVGCDTCGRCRLEDTLYVCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAAQTP
RRLSPQPTPRSQPES
>A0A7R7CAX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L-8-3|TrEMBL
MDTTSPLHKARPQFIGASTELAPGQAIDSPDLPGLFPQGVRVYITDIGTDDTPTLVRAAR
RVTDLGYTAVSHIACRRQTTRIALEERVRALAEEAGVGDVLIIGGDVKTPAGVFSSSMDV
LETGFLDKYGIAEIGIAGHPEGSRDFSDEVANGALRLKQAWGERTGARLRIVTQFGFDAE
KFIAWADGLAGLGIDLPVHLGVAGPAKITTLLKYAAVCGVGNSLSFFKKRSASLAALATS
HSPESFVSPVEEHFRANPGSAIEQLHVFPFGGIKNASRWLHERGSWASEERPAARLEFRT
H
>A0A4R0MRR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter hiemivivus|TrEMBL
MKIIDHINNAKGKTLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDNAFIPTPNGHAYASELLQHVADMNKGKYLHDDMESAEKTDFCIGVAGY
PEKHFESPNLDTDFKWLKHKVDTGADFIVTQMFFDNNKYQEFVDKCRANGINVPIIPGLK
PITSSKQLISLPKIFHLDIPLELSEAVQACKSEKEVKEVGIEWMINQCNELKAMGAPVLH
FYTMGNPEPTKRIARAVF
>A0A534K0E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MEAGPPPASSKSGSRLERVLAANEFAVTAEVVPPASPDPAPIVAAARRLKGYADAFNVTD
GPRARVHMAPWAGGAILLREGLEPVVQLTTRDRNRIALQGDVLGAVALGVRNVLALSGDD
PKVGNEPDAAIVSDLTTEAFIETMRDLRDKGVFRGGDPVETRPRVFIGATANPFGGPMED
SFVNLRGKAEAGADFVQTQAIYDLDAFDEWMHLVRKEWLHEKLHILAGIVPLKSAKAARF
MAEKVPGVVLPRDILSRFERASDPAAEGLRIAAESIEALRKMGGVHGVHLMAVNWESAVP
VIVKRAGLYPRPPAPDPAVE
>A0A6L8LX57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. OCN044|TrEMBL
MGYTHAGHIDALNQNIAELADNINVSFEFFPPSSEKMEETLWSSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAQTGLVAAPHLTCIDASREELIRIAEDYWANGIQSIVALRGD
IPPGGGKPEMYASDLVTLLKQRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQN
>A0A8D5ZQH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atopobiaceae bacterium P1|TrEMBL
MATKTVSQIFATQKLPVSFEIFPPKGDLSQEEAQQVASQLAPLDPAFISVTYSAGGSGNS
SRTLEVARLIQRDYDVSTVAHLTCQGLTRQSLAKKSAHLKEAGIKNVLALRGDPNPEAAP
GDFEYASDMIPQLVEDGFCVGAAAYPEGHISCLDPDIDVAYLRGKQDAGASFLVTQLFFD
NQLAYRFRERCHKAGITVPITFGVMPFLSKSQVSRMIFMCGASLPSAVVKLLARYEDDPE
SLRAAGIEYACAQLQDLATHGVDGLHIYTMNRPQVAAAAVAAIREVL
>A0A8H9ICH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraglaciecola oceanifecundans|TrEMBL
MVSYAQGIDALNQSLSEVKGINVSFEFFPPKTETMEKTLWKSVERLAPLKPKYMSVTYGA
NSGERDRTHEIVKRIQSETGIAAAPHLTCVDASREELKQIAKDYWASGIRKIVALRGDLP
EGYTEHVSYASDLVALLRDVADFDIAVAAYPEKHPEAPNSQFDLLNLKRKAEAGANQAIS
QFFFDAEVFLRFRDRAAAAGIDMDIVPGILPVTNYQTLQRFAGFTNVHVPNWLHKMYDGI
DKDDQTTRNLMGASIAMDMVKVLAKEGIRDFHFYTLNRCELSYAICHMLGVRAD
>A0A4R3MAC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidamorphus gemmatus|TrEMBL
MEATRGKRPGGGPNLAVSFEFFPPKTAEMEASLWKAVERLAPLCPHFVSVTYGAGGSTRD
RTHQIVARIARETDLRPAAHLTCVDASREEIEEVIYAYWDAGVRHIVALRGDPAEGVGAR
YRPHPHGFQTTAELVEGIRRIGNFEISVSAYPEKHPESPDFDTDIDVLAAKVDAGATRAI
TQFFFDNAYFYRYRDRLAARGIDIPVVPGILPISNFAQAARFAERCGTHIPESFAARFEG
LDQDPETRLLVAASVVAEQVLDLLDNGVSDFHFYTLNRAELVYAACHMLGLRPALTTSAA
A
>I9WFD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. Rr 2-17|TrEMBL
MTASPRPAEQPLFAGLPGDISVSFEFFPPKTEKMEAQLWDAINQLAPLDPSFVSVTYGAG
GSTRERTHATVARLVRETHLVPAAHLTCVGASKAEIDEIADQYWDAGVRHIVALRGDPPP
TDGGRFVPHPQGYASAAQLVEGLRCRHAFDLSVAAYPEVHPEATSAEADLDNLKRKIDAG
ASRAITQFFFSTDAYFRFLDKALAAGITAPILPGIMPVTSFAAIRRMSGNTEIPAWLETM
FDGLDDQPGPRALVAAVAAADLCKRLYEGGVRDFHFYTLNKAEQAYAVCQLLGLRPKEPI
E
>A0A2E1V5L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geminicoccus sp|TrEMBL
MTDTKQAVVNLFSDFTVETTPNSASKIPDFNARLRNDTPVYVTFLPGSDVYETVTVAKRL
RGEGFNPIPHIAARSIQSEDMLSEILNRYVGEAGVEHVLTIAGGVDNPLGPYDSSMAILE
SGMIDKAGIRKVSVAGHPEGSPDITDEAIKDALAWKNGFAERTGAQLDIVTQFAFEAEPL
IAWDRRINAEGNTLPIRIGLPGLATIKTLLGFSKAAGVGNSIRFLMKRAADVTKLMTVNA
PDKQVIDLARYVAEDANAGICGVHMYAIGGLKRTSAWSYALRDGLFDVNARDQIKVTVDL
G
>A0A2R8CCU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falsiruegeria mediterranea M17|TrEMBL
MTAPDISFEFFPPQNLEASFRLWDTVQTLAPMNPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNASKVETLAIADQFAAAGVTDIVALRGDPPKGQGQFTPHPEGFANSV
ELIEALAATGKFNIRVGAYPDIHPEAQHAQADVDWLKRKLDAGADEALTQFFFEAETFFR
FRDACAKAGIDKQITPGILPIENWKGARNFARRCGTNIPQWVEDAFAKAVRDDREDLLAT
AICTELCSDLIDGGVDKLHFYTLNRPELTRDVCHALGVVPKVDLQNVA
>A0A2D6C0B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geminicoccus sp|TrEMBL
MTDTKAAVMKLFGDFTVETTPNSAAKIPDYNVRLRNDTPIYVTFLPGSDVYETVTLAKRL
RGEGFSPIPHIAARSIQSVDMLRDILDRYVGEAGVEHVLTIAGGVDNPLGPYDSSMAVLE
SGLIDKAGIRQVSVAGHPEGSPDITDELIKDALAWKNGFAERTGAALDIVTQFAFEAEPI
IAWDKRINAEGNRLPIRIGLPGLATIKTLLGFSRAAGVGNSIKFLVKRAADVTKLMSINA
PDKQVIDLARYAAEDPKAGISGVHMYAIGGLKRTSAWSYALRDGLFAVTGKDQLKVSVDL
G
>A0A2S0QU93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zoogloeaceae bacteirum Par-f-2|TrEMBL
MQAIELSIEFFPPQTPEGAEKLRTVRDRLAVLQPAFFSVTYGAGGSTRERTFATVQEIAA
AGFEAAPHLSCIGASRAQLRAILKEYEEAGIRRIVALRGDLPSGVGTAGELRYASELVEF
IRAETGRRFILEVAAYPEWHPQAKSPRDDLLAFQRKVAAGADSAITQYFYNLDAYLHFVD
EVRALGIDIPIVPGIMPITSFAKLARFSDACGAEIPRWMRRKFESFGDDSASIRAFGLDV
VTDLCQRLLDAGAPGLHFYCMNQAEPTLAICERLGLGPHAR
>F4LLK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema brennaborense (strain DSM 12168 / CIP 105900 / DD5/3)|TrEMBL
MKLSKLFKKGRQSFSFEIFPPKHDEALRDIGETLDILAGCSPDFISVTFGAGGSETGRRT
IDLAKRIKNEYALEPLVHLTCLNGTEAEVEGWLHELEDAGIENVLALRGDRRGEAATGSR
FSYASDLVSFIRTRFPSFCVAGACYPESHPESPDRVSDVRALADKVRAGTDFLISQLFFE
NGLFSGFCERCRIAGITVPVAAGIMPVVNKKQIEKMTGLCGASVPPQLARILDRYGDNPA
ALRDAGLAYAENQIVDLAASGADGIHLYTMNNPAVAKQIAEGIKNILPHRAPVSA
>A0A2N2G679|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-23|TrEMBL
MTVNSSNLQKKLSRGEFVVTVEVCPPKGCDTRLFLQQSKELSGIVDAINVTDNQGANMRI
SPLAASLLLQREGLEPIMQLTCRDRNRLALQSELLGAAALGIKNILALSGDHISFGDHKE
AKAVFDLDSVQLLEAIKCLESGSDLSGKSLDGIPSFFIGAAAAPEAEPFELTLFKLRKKA
AVGAQFFQTQAVFNPAKLARFYDSVKPLGVKIISGILLLKSAGMARFINKNIPGLRVPDE
FIAELENSANPAFTGVEIACRLARAVKPWSDGVHIMAMGREEVIPEIVSAVK
>A0A2U8DXT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium drakei|TrEMBL
MSLLKEAFERGEFGITAEMAPPKGIDLSHLIECAKAIKGRAHGVNVTDFQSATLKATSLA
TCKVLKDAGLEPVLQITGRDRNRIAIQGELLSAGVFEIENVLALTGDYTMTGDHPGAKPV
YDLDSVGILSVASTIAQGKDMSGNDLTGTPKFYLGACVTPRYDPLELQILKMEKKIKAGA
KFFQTQAVYDIDTLKIFREKTKHLDAKLMVGIIPLKSAGMAKYMNKNVPGIFVPDELIER
MKGAENKVQEGIKISGEFIKKVKEEGLCDGVHIMAIGAEENVPLILDQAGL
>A0A1S8VZS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Batrachochytrium salamandrivorans|TrEMBL
MKVTDKIQKANDEGRCFWSFEYFPPKTDSGVMNLFDRMERMYMLGPEFIDVTWGAGGTTS
GLTLEICSTAQSVFGLETCMHLTCTNMPRAKIDEALEQAKNAGIMNILALRGDAPRGQEN
WTKVETGFSYATDLVRYIREKYGDYFCIGVAGYPEGHIENPDIEDDLIHMKEKVLAGADY
IVTQLFYDVDIYIKWVARLRSMDITIPILPGILPIQNYSGFKRMTSLSKTFVPQFILDDL
EPIKDDDQAVKDYGIRLAMQMCIKMKEAGQRGFHFYCLNLERSTRLILEGLEFIASRETV
KPLPWNPSLGKNRERETVRPIFWRNRTKSYIMRTDAWDEFPNGRWGDSRSPAYGDIDGYG
VRLKYPATECLNIWDFPETTSEVCNLFYKYCMGELNSLPWSDSSLLPESEVLRNRLANVN
RNGFLTINSQPAVDGALSSDPVYGWGPKNGYVYQKAYLEFFVSPSKLDVLIKKISEHPFL
TYHAVNKGGDLKTNIKGDSPNAVTWGVFPGQEIVQPTVVEGISFLAWKDEAFELWNQWSL
LYEKDSTSNKLINNISCSWFLINIVDNNYKNRFAIYDILDQVASETTDVVNH
>A0A1B3X567|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp. oral taxon 920|TrEMBL
MAQERMTIREHLKKEPLVFDGGMGTYYAQKTHTRGKGVELANIETPRVVEEIHTEYLRAG
AQAIKTNTFAANRIVYQGEEALVQGIIRTGWELAARAAEPFNAYVFADIGPVTGMPRADI
IEENCFLVDTFLALGARHFLFETNSSAEGLVETAAHIKQIAPDAFILTSFSAFPGGYTRD
GYFVEELVREVTESGYIDAVGFNCVSGVQSMKELVRLLGTCTLPLSLMPNAGHPIVIDGR
TFYESAPDYFGEGLAAVAREGVTIVGGCCGTTPEHIRALCKALEGGAAAEGAHVQQERTE
LTPSHSPFFEALQAGQIPIAVELDPPDTGNADKFIAGARELQAAGVHAITIADNPIARAR
MDAAMLSGRVQRGLGLEPIPHMTCRDRNLNAIKSILLGLSAEGIHNMIAITGDPIPTAER
DEVKSVYQFNSRKLSAFIKSLGERGDVVPFHVFGALNVNAKHFPSQLGLAKKKLEAGMTG
FFTQPVLSARAKENLRTARDTLPGALILGGIMPVVSERNARFMESEITGIHVEERIINAY
HGLDREAAEELAVKLSLEIAKDIEPYIDGYYIITPFARTALVARIVAEIKARRAGQ
>A0A847ZYN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacteriaceae bacterium|TrEMBL
PPKAGDGEESFWSTVKRLETIGPDFVSVTYGAGGTTQDRTLATLRRITSETRLAAAGHLT
CVGKSKEDVNSVIRSYAEAGVKHIVALRGDPPAGVGTKFAPHPEGYRNAADLVRGIREIG
QFDVSVSAYPERHPDSVSIEEDLAFMADKAENGATRALSQFFFHNAFFLRLRDRIAARGI
KINLVPGILPITNFARVCEFAGKCGAHVPPDLERRFAGLDKDPETRNLVAAMVAAEQVHA
LAREGVTDFHFYTLNRADLVYAICRVLGLGGPAQDEAAA
>A0A7S2L9C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Skeletonema marinoi|TrEMBL
MPRIIDKIRAVQYERIAVSSQSSSSSSSSAATNTTSEDVSSDDVQPGWHYSFEFFPPKTE
AGLDNLLTRIDRMSRRLNPLFVSITWGANGSTLSRTLAIASHAQRFACVDVLLHLSCTGL
TREQIAQILNMAKSSGVRNILALRGDPPHPKRAWKEGDVSGGDCDRAIDLVKLIRKLHGD
YFGIGVAGHPEGHPSSLKCDDGTTTSLEMQHLKDKLDAGADFVITQFFYDVDIFLEYVKR
CRGIGIKCPIIPGIMPIQSYSSLLKMTSFCNISVPSSVLDRLERVRLDDEAVKKIGCEIA
AEMCRRILAETSSTSSSAVDYSIGDDCSVHGFHFYTLNLERSTTRILASLGALDIDSPTS
AGAALQENDTDATIGSETNDQDQIVTRRERKESISEKARST
>A0A7V4G9X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans|TrEMBL
MKLTELFRQGKFVITSEVGPVKGCSRVNGGPPPEFIQEAVNIKDFVDAVNVTDNQSAVMR
LGSLAASVLLKQQGIEPIFQMTCRDRNRLALQSDLLSACTLGIDNVLCLTGDHIKLGDHV
ASKPVFDIDSVHLLHIARGLNQGRDMMGNPLSRATDLALGAVVNPNFEPLDLQIMKMEKK
IEQGAEFFQTQAVYDPKVFETFVRRAEGFRVPIQYGLVVIKSPKMAQYMNEHVSGITVPE
ALIKEMASVPADGYKAKAQEITLRLARELGTMVQGIHFMPLGWSELVPPVVTELRKLGK
>A0A812PRH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiodinium necroappetens|TrEMBL
YGGEGTRRETLGRLRERPECVVGTVGRLIDFIENEKHWFGVRNVRFLILDEADAMIGEGL
DANIRKITCDVETPRRQTMLFSATFADDVSDLATWISRHAVEVRVGMKDPLRANRDVKQE
VIIVKDEFDKEGALKSTLRKVYSAHNKSPGKVLIFAFDHDECDSLAKKVKAALNGVPVET
LHGYKKQAERETAMQRFRNGDSWIMVATSIAGRGLDIKDITLVINFDPPEVPPGWFSFEY
FPPKTPEGVENLRKRIVKMKSLGPLFTDFTWGAGGSTSELTLKLTSAAKNEFGTVANMHL
TCTNQSSEMTGNALLECKQHGVRNIVALRGDPPRGQEKWTATEGGFSSALDLVKFIRQNH
GDYFSVSVAGYPEGHPDNIEVVEGGVAALTASEKRRARVVTDAQGKEVVTVCRDANFHKE
MVYLKEKVDAGSHFVITQMFLDAQVFLDFVDECRKYDIKVPIVPGIMCLNGFGGLKRMTE
LCKTRLPEGFPVLHLA
>A0A7W7T6X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix violaceirubra|TrEMBL
MTSVVERLRRDSPGFSVEFFPARDDADEAVLWRAIRELEPLDPSFVSITYGAGGSSRDRT
IRTTARIAQETTLVATAHLTAVQHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGEWT
PQPDGLTYAEELVRLCRELGDFCVGVSASTYGHPRSPDLDTDTKHLVSKIRAGADYVIAQ
LFFRPEDFLRLRDRLDAAGCGDVPLLPGLMPLTTKRTLAKTVELSGADVPDEVSRRLDPY
LDDPAAFRSAGIDLATETGARLLAEGVPGLHFYTLNRSKATREVVGRLGLVPARA
>A0A7R9SMH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Argulus foliaceus|TrEMBL
KFLDMANDRSSILTNINSKIESKTPFMSLEYFCPTNVEKYDELWDCITVLSSYNPVFCSI
TCQGPKKRAIITPTELASRIIHCFGLDCILHVTGLYHNKSKVLEILKVCKDNKISGVLAL
RGDMVQNHQDVGFSHASELVRCIASQRSNLIIGVAGYPVGHPESRSLEEDISYMKKKVEA
GADFVISQFFFQTEDFETFLSNCRSTIINALILPGFLLYSSYDQLTGILDRAEMSLPEHI
RLILEPIRHNDNAVKNFCIDHTAEMIKSLLYKDITLGVHFFTLNRSDILVNVAAQCGFHV
HAIKLTATKHISTNSTQDDLSSRIFVNSSGRVIKLDDNLERCCSPEPGEGGDLISKLTGI
LHHTEYENELCILFAKLSKLGVCVVNYQKSVKKHSQEGDVVYQKGFCELITNMSNSKCLE
NIIANYKNIYYCIYSLPENKIVNMVPNISVTWLQSPGRVTESLLHFDPLHYKMLTFSRMQ
GFMNGKTTDKDVCFMLLVEKTMNSTSCLLGMLEKYINGKTTT
>A0A547PY09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenimaribius caenipelagi|TrEMBL
MTRISYEFFPPKSLEACFRLWDTINALAPTCPDFVSVTYGAGGTTRQLTHEAVTTINKST
GLRVAAHLTCVDASRDETLEIARSYAEAGITDLVALRGDMPGGGAFAPHPDGFASSIELI
EALAATGDFTLRVGAYPDRHPDSLTAQADVDWLKRKVDAGASEALTQFFFDPATFLRFRD
RCAAAGIDAPIVPGILPIESWKGVRKFATACGMEIPGWLDDAYQTAERDNRQELLSTALC
VELCDKLISEGVDKLHFYTLNKPHLTRDVVHALGLAPEPELDQVA
>A0A2S7E151|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. hederae|TrEMBL
MYPDTPSLASTITDAYSLEVSATDIPGLTAAAPRILRGSTIAIPYLPSQNDDARLAAAQR
VRTLGFAPMPHLSARRIASLDALHAFVGRAVDEAGVERCLVIAGDAPSAIGPFSDSLSLI
ATGAFERLGIKTIGVAGHPEGHQSMPATDQWDVLERKCRSIAERGMAPLIVTQFAFDADI
VLTWLEALRARGIAYPVRVGVPGPAGVAVLARYAARCGVGACASMLSKYGISIGKLFGSA
GPDRFVDRLATGLTEAHGDVSLHFFPFGGIAQSVTWVEQYRSRSAAHILSTAASRRSQ
>T1J9I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strigamia maritima|TrEMBL
MTSLEILSNRYQNNVEFEQIKSDENGCEGDGTRCHHHPESSAYLSLIERINQHIHTGEKF
FSLEFFPPRTNGGAVNLLTRLNRMRVGGPLFCDITWHPAGNPGGDSETSSITIASAALNY
CGLETMLHLTCVNQTKNEIRSHLTRAKELGIRNILALRGDLSVDGRWSPGKSRFFYAVDL
VRFIRKEFGNYFVICVAGYPTGHPDAASYNEDLQHLKEKVEAGADFIISQMFFKANRFTQ
FVTDCRNIGIQVPIIPGIMPIQGSDSLRQIVKLAKLEVPKEIIDDLIMLKDNNEDIRSYG
IKHAVNLINELFETGLAPGVHIYTLNREVAATTVLERLGLWCKEPYRPLPWKLAANYKRC
REDVRPIFWSARPESYIYRTRHWDEFPNGRWGDSESPAFGELKDYYLFFMANHSSENERL
QMWGEELTCEQDVWNVFYSYISGECNKNGVKVTTTAWNVEELSAETYLLQNKLSTVNKRG
ALTINSQPNVNGISSTDSALGWGFPGGYVYQKAYLEFFACKQYVTALRQILPKFSQVNYH
IINSSGNENYTNSHKHKPVAVTWGVFPGKEIIQPTVVDPVSFKAWKDEAFALWKEQWGKL
YDDDSQSRRIINHIHDTYCLVNLVDNDYPKESCLWNILEEMFEKSEPLSNDSFESAINDD
YLADKIV
>T1J9I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geophilus maritimus|TrEMBL
MTSLEILSNRYQNNVEFEQIKSDENGCEGDGTRCHHHPESSAYLSLIERINQHIHTGEKF
FSLEFFPPRTNGGAVNLLTRLNRMRVGGPLFCDITWHPAGNPGGDSETSSITIASAALNY
CGLETMLHLTCVNQTKNEIRSHLTRAKELGIRNILALRGDLSVDGRWSPGKSRFFYAVDL
VRFIRKEFGNYFVICVAGYPTGHPDAASYNEDLQHLKEKVEAGADFIISQMFFKANRFTQ
FVTDCRNIGIQVPIIPGIMPIQGSDSLRQIVKLAKLEVPKEIIDDLIMLKDNNEDIRSYG
IKHAVNLINELFETGLAPGVHIYTLNREVAATTVLERLGLWCKEPYRPLPWKLAANYKRC
REDVRPIFWSARPESYIYRTRHWDEFPNGRWGDSESPAFGELKDYYLFFMANHSSENERL
QMWGEELTCEQDVWNVFYSYISGECNKNGVKVTTTAWNVEELSAETYLLQNKLSTVNKRG
ALTINSQPNVNGISSTDSALGWGFPGGYVYQKAYLEFFACKQYVTALRQILPKFSQVNYH
IINSSGNENYTNSHKHKPVAVTWGVFPGKEIIQPTVVDPVSFKAWKDEAFALWKEQWGKL
YDDDSQSRRIINHIHDTYCLVNLVDNDYPKESCLWNILEEMFEKSEPLSNDSFESAINDD
YLADKIV
>A0A2N2C679|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-19|TrEMBL
MHNPLDHIKNKIYHVEILPPKQESTKLLADLDVFKEKYLRVMDSGYCACITDNAMGLMAF
QGHEIIEEMNLPVHPDQIMIHLNTFHTKADLDNILRCCKNLGIESLLVITGDGSDRLPKL
QPSDIDESDIEAVTSVELLRYIQRVYPDTFVLGVAFNPYEPSDHEFAKLKRKIKAGASFI
ITQPIIEQNTQVDRLLAEYPNIPVTVEAWMSKKLSLLSDAIGYKISEDTQFDPIATLEML
HQTYPQCGVYLSLVGFKTQYDLIKNLWI
>A0A1S1BSG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aerococcus sp. HMSC035B07|TrEMBL
MKTKELFKEKTVFSYEVFPPKKTSGPQSIYKTLEELKSLSPDCISVTYGAGGGDNNDESF
KIAQTIKGYGIESIAHLPCVGMTKADLEEKLEELKALKVENILALRGDLPADDYEPGDFS
YASDMVRFIKDKGDFNVVAACYPEGHVDCKDKVQDIKHLKTKVDAGVDQLITQLFLDNND
FYAFRERCELADINVPIEAGIMPVVNKRQIERMTSLCGVKLPDKFVKMMDRYQDKPVAMR
DAGIAYAVNQIVDLISQGVDGIHLYTMNNPYIAKKIHEAVHNLL
>A0A849KLK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ochrobactrum] soli|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKSEEMEQRLWETVTRLAPLQPEFVSVTYGAGGSTR
ERTIRTVARILKETDIKPAAHLTCVDATREEVDRVVREFADLGVNRFVALRGDPAAGIGE
KYVPTTGGYLNGADLVGGLRQIADFDISVSAYPEKHPESPDFATDIDMLKRKVDAGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPAWLAERFD
GLENDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPYAICHMIGIRPKTEAVL
EPA
>V9FVT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora parasitica P1569|TrEMBL
MGKIIESIRSAYAARADDASARPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGAERWSPVEGGLSNAVDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIQWISDCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPEKVLTALDAIKNDDAAVRRYGTQLAVETCRRLLAAGVNSLHFYTMNLATT
VTQVLEGLQLLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRTELWGTPQTEEDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAAIRENLQWLNSNGFLTINSQPRVNGAPSSDPSVGWGGDDGVVFQKAYVEFFVA
PEKIAHLVKVMRRDYPQLSFHALNRRGDEHRNTPLHSVTAVTWGVFPGIEIVQPTVVDSD
SFAAWKDEAFELWQTQWASAYPEGSCSREVIQHIYDSYFLVNIVDNDYANDDSDIFSIFT
RIITEAMDKEELRTRVLELEARREKMFDTLASFQSLQKDLNGELRAAHSELAGVRGENLQ
LKEKVRQLEAQLALASL
>A0LY75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gramella forsetii (strain KT0803)|TrEMBL
MKVTEHIEKANGKTLFSFEIIPPKKGKNIQELYDNIDPLMDFKPPFIDVTTSREEHLYVD
RDGLFDRKITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFSREETEYLLVDCHYLGIENV
MALRGDAMSHQRYFEPSNGGHPYACDLVKQITNLNKGKYLHDVIEADDLADFCIGVAGYP
EKHIEAPSLNSDLKRLKEKVDAGADYVVTQMFFDNSKYFEFVEEAKKAGINVPIIPGIKP
IAISRHLQLLPQVFKIDLPESLILEVEKCKTNKEVRQVGVEWCIQQSKELMEGGAPVLHF
YSMGKSSNIEQIANAVF
>K4XKW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O111:H11 str. CVM9455|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2A6L1B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. L9|TrEMBL
MALKSEGRGRNFGISFEFFPPKSEEMEAQLWDAVAKLQDWDPDFVSVTYGAGGTTKAPTL
SAVTRFLSQTPLATASHLTCVGATKEETHQMIDTFRKVGVKHFVALRGDAPGGVGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRNTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGISIPIVPGIMPIQNLTQLKRFAGACGAVIPAFLDERFAGFDD
KPEDRAKVAAEVAAEQIEDLVRRGIGDFHLYTMNRAPLVSAVLDNLGYSRRAAKSAGAAA
>S5RY01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium etli bv. mimosae str. Mim1|TrEMBL
MALKNEGRGRNFGISFEFFPPKSEEMEGQLWDTVAKLQDWDPDFVSVTYGAGGTTKAPTL
SAVTRFLSQTPLATASHLTCVGATKEETHQMIDTFRKVGVKHFVALRGDAPGGVGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGISIPIVPGIMPIQNLTQLKRFAGACGAVIPAFLDERFAGFDD
KPEDRAKVAAEVAAEQIEDLVRRGIGDFHLYTMNRAPLVSAVLDNLGYSRRAAKSAGAAA
>A0A4Y8M827|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. B2|TrEMBL
MREPTAGHERPVRGFEMICEIEPPTRPDLTHARHQIGVLSPVTDAFLIPDNHIGRATVSS
IAVAHEVATMGGRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVHGDKPTAGNRTGDL
TVRAMMDEARAASEDPVFADMPAFRVGAAAGLRPLPTWKRAADFLFVQISYSVDALLRWR
DAHPVELPIYAGVMVLASAGMARRLAAAIPDIDIPDDLVQAVERDQAAGVEAACDQVLRL
RDSGAFAGVHLVPVSRYRQVATRLEDLL
>A0A1V1WA27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. PD653|TrEMBL
MIRALTADDSSTRTALKRAFENLGYEVIPLKGTEEQVLHHVPTDVRLTVTASPAKGQDAT
VDLAVKLARHGYSVAPHLSAQQVRDRAHLADLVARCREAGISHVFVVGGDPTDTPTDFKH
AHDLLVALHELDHGFTDIGIGGHPEGHPAVPEEVLFQALKDKAELATHITTQIVFDPATI
LTWSRELKRRGIDLPIQVGVPGAVHRQKLLRVSGGLGIGASADFLKKQQNLFWRFFAPGG
YNPARIIKGLAPHIGKPDNTLDGFHIFTFNDLHATEAWRTKTLEALA
>A0A3N6SB48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia psidii|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPSDGGKPGMYGADLVALLREVGDFDISVAAYPEVHPEAKSAQADLINLRRKIDAGANHA
ITQFFFDVEGYLRFRDRCVNAGIDVEIVPGILPVSNFKQLQRFAALTNVRVPGWMNSMFE
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAVSH
>A0A550CL75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Auriculariopsis ampla|TrEMBL
MKISQKIQQSSKDDKVWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPKEKVDIALKDAKAHGCRNILALRGDPPSGKDE
WEATEGGFVHGIDLVRHIRHEYGDYFDIAVAGFPQHMLLPEEERAQEMRWLKEKIDAGVN
FIFTQMFYDVEIFISWVREVRAAGITIPIVPGIAPIQTWNGFLRATSLAKTVIPQNFMDA
LEPHKNDDERVRAIGTKLVAEMCRRILAEDIGIKGLHFYTMNLEKATKMLLEELQLVPRV
ETIKPLPWRQSLTPTRRAENIRPIFWANRTRSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVSIKQTKEDALKLWGEPLAVADICRLFSQRCMGQLKALPWSDQELNAETNVISTQLA
RMNELGFLTINSQPAVNGVRSDDRIFGWGPSNGYVYQKAYLEFFVSPTLLSLLLSYIEQD
SNITYYVINKNGDLRTNTRSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAYELGQQ
WAKVYGPDHPSYKLITELMDTWYLVNVVHNDFQDRNAIFQPFIKAGEEFAAKATAGAQ
>A0A1N5YM24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora cremea|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTEAGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVSVTERIATDTTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPAGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFEADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQASEMSRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARM
>A0A1C4H277|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium commune|TrEMBL
MHSPIFSLEVFPPKSHTPVGTIYDTLDGLGGVDPDFISVTYGHGALQDRSLTARIANTIR
HDYQIPVVAHLTALYSDKKIIDEALGMFHQAGVSGVLVLRGDPVEGHAPCGVFEHSSDLA
AYIHEVDPKMKIFGACYPECHLEASCLEVDVDNLAKKVDAGVTHLITQLFYNNDDFYRFL
DLVRSKGIDVPIEAGIMPARSAKSINSMTARNGCKISPEVRAIVERWGDDPSSLLQAGIV
YASEQIVDLVAHGVDGIHLYTMNRPVLARRIWANVESLFAVN
>A0A543D1B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia kunmingensis|TrEMBL
MTGRLAAAIGEGRFAVTAEIGPPRGADAAAIERKAGLLRGWVDAANITDNQGAHVRLSSL
AGSVLALRAGVEPVMQLTCRDRNRIALQSDLLAAGALGVPNVLLLSGDHPVYGDHPDAAA
VFDLDSVQLVWTARTLRDEGVLLSGRPVETRPQFLVGAVENPFAPPAAFRATRLGKKAAA
GAQFCQTQFTFDVPAFARFMAEVVDRGIAQRCAVLAGVGPIRSLRAYEFVRTHVPGVHLP
ESVGRRLRGVPEHRVAAEGVALCVETIEALRAIPGVAGVHVMAFGYERGIPEILERAGLA
PAAPTERKERA
>A0A716TAV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Typhi str. CT18|TrEMBL
MSFFHANQREALNQSLAEVQGQINVLFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6N7DY86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenovibrio sp. JE_KL2|TrEMBL
MNSQKKYPQKLSLEFFPPRTPAGVDKLKTVITELGGMAPEYMSVTYGAGGTTQEKTLETV
SYIQQHTPFDAAPHLTCIGATHESVLELLNTYEALGIKRIVALRGDLPSGMMDPGEFKYA
SDLIAFIKQEKGDTFHLEVAAYPETHPQARNCEVGIKWFKHKVEQGADSAITQYFYNVDS
YLYFIDNCERHGIDLPIIPGVMPITNYENLVRFSAGCGAEVPRWLKCRLESFEDDKESLL
AFGQDVVTEMCQRLLDAGAPGIHFYSMNQSQPTLDIAKSLTFKNA
>A0A5E4NZS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beijerinckiaceae bacterium RH AL1|TrEMBL
MSGASIRHTSFDSVLAALTAAGEPTRLRLLALLCDAELTVSELVAILRQSQPRISRHLKL
LVEAGLVERHREGAWVFLLVAQSGTAAHLAREIVAAADPADPVLAADRARLGEVRRARAA
QAAGYFATHAANWDELRAMHVAEDKVEAAIRAAVGDAPIGSLLDVGTGTGRMLELLAPQA
DRALGIDQSPQMLGIARDRLGRAGLRNAQLRQGDIFALPVERDAFDLVIVHQVLHYLDDP
SRALREAARTLHPGGRLLVVDFAPHQEESLRAAHAHRRLGFSHDEIAAVMADAGLDVTLT
RDLAPEGAGTLTVSLWLGRDRRIQSDALPSPCWKSPKMQSAAMTRLSRGHRPRFNVSFEF
FPPATPEMEATLWESIRRLAPLNPSFVSVTYGAGGKTRERTHATVDRIISETHVRPAAHI
TCVAATKDEVDAVARDYWECGVRHIVALRGDPQTGPGTAYVPHADGYRSSTELVTGLRRI
GDFEISVSAYPEGHPESASIDADIDVLKAKVDAGATRAITQFFFDNDVYARFLDKVRAKG
INIPIVPGIVPVQNFKQTAGFAKRAGASVPAWLAERFEGLDDDPATRRLVAATVAAEQVL
DLVDRGIYNFHFYTMNRADLVYAICHLLGMRPVYREQKAA
>A0A667IQF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lynx canadensis|TrEMBL
MVNEPRGDGGPTSRSEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRH
IRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMW
GEELTGEESVFEVFACYLSGEPNQNGYKAYLEFFTSRETVGALLQVLKKYELRVNYHIVD
VKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEE
SPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A7Y7NCT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium|TrEMBL
MRIADLIAHKKPFISLEFFPPKEKAEWPAFFGTVERLAQLDPLFVSVTYGAGGSTQSDTL
EIVTRLTRDHGLEAMAHLTCVGATPEAIRAFLDQLSKAGVHNVLALRGDPPKDAPAEFAT
CKELQYASDLVTFIRSGYPDLGLGVAGYPETHPEAESPRSDLEYLKLKLDQGGDFIITQL
FFDNQSYFDFVRRARELGIEKPIIPGIIPVVSLKVINRIISLCGATIPAAFMAELEEADR
RGGAAAVQDIGVAYARRQAQELLASGAPGIHLYTLNRADVILELTKGLLP
>A0A2B7WWA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomyces parvus|TrEMBL
MHIKDKLAHAEAIGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDDQDDPELLMEHLKEKVDAGGTF
VITQMFYDVDNFLTWVEKCRESGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEAL
EPVKNDDAAVRNLGKSLVANMCKKILASGIYHLHFYTMNLQQATKMVLDELGLIPSHKTP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIKLWGEPKSLKELSEIFIRFLDGSLDRLPWSEGAVTEETEIIKPNLLD
LNRKGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLIPPTMIDDLINRIEQNS
DLTYYCVNKAGELKTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHAPSSPSRRLIEQVMDSWYLVNIVNNDFHKTHDIFNLFKDLKVENLDTEIEPIAPAAE
PVGNAQQNGQPPQTEANGSVMDATKSVQAHNTN
>A0A1I2XL52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira sp. Nsp14|TrEMBL
MESQKKFAPTFSFEFFPPQTPEGIEKLRATRRQLAQLDPKFFSVTFGAGGSTRARTLDTV
LEIQAEGYTVAPHLSCIGATGENIRNILKQYRDRGVRHIVALRGDLPSGMAQGGEFRYAS
ELVAFIRAEFGDAFHIDVAAYPEYHPQANSAQEDLRHFKQKVEAGADSAITQYFYNADAY
FSFVEACEAMDISIPIVPGIMPINKFSQLARFSDACGAEIPRWIRKRLEGYADDSASIRA
FGLDIVTDVCDRLLSGGAPGLHFYTLNSAGLTSTIWQRLGL
>A0A077DBU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Basilea psittacipulmonis DSM 24701|TrEMBL
MGYAKHINVLNQSLAELDGNINVSFEFFPPKNEEMEHILWSSINRLAPLKPKFVSVTYGA
NSGERERTHSVVKAIQQKTGLIAAPHLTCIDATKEELSQIAKDYWNNGIRNIVALRGDEP
VGYEKKEFYASDLVKILKDVADFEISVAAYPEVHPEAKSAQADLWYLKQKVDNGATRAIT
QFFFDIDTYLRFRDRCAAIGIDVEIVPGILPVTNFKQLLKMATLTNVKIPQWLSKRYEGL
ENDPITRNLIAASVAIDMVRILSSEGVKDFHFYTLNRSELTYAICHTLGLRADTSAV
>Q2BAQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. NRRL B-14911|TrEMBL
MSLLDKMEKEIIIADGAMGTLLYSYGTDFCFEELNVSQPGHIQNIHQAYIDAGATLIQTN
TYAANYLKLQRYGLEDHVKEINSAAVTVARKAAGNHAFVAGTIGGNRGIKPHSISIEEIK
RSFREQLYCLLMEGVDAILLETYYDLKELETVLSIARKETALPLIAQVSLQETGIMQDHT
PISEALSRLDALGADIVGLNCRLGPHHMLLTLEEVPLPQKAYLSAYPNASLPAYTDGKFH
YEGDAEYFRQSAKAFRNQGVRLLGGCCGTTPAHIRAFSDELKGSPPLEKKEVREPKAKIR
IMPKEAQRDLPPLQDLVKKRQSVIVELDPPRKLETDKFFAGAKALQDAGIDAITLADNSL
ASPRISNEALGYLAKNRLGLRPLIHLTCRDRNIIGLQSHLMGLHTLGLHDILAITGDPAR
VGDFPGASSVYDMSSFELIQMIKQLNEGRSISGKDLGQKAAFSVAAAFNPNVRSLEKAVQ
RLEKKAECGADYFITQPVFSEEKLMEIYEATKHMEQPIYIGLMPLTSSRNADFLHNEVPG
IKISDKIRERMNSLKDDPLQSVREGISISKELIDAAAELFNGIYLITPFMKYELTAELAA
YARSEKLKTARRSRNAKDFSI
>A0A8F6BPB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. R2A056_3_33|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVD
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VVALRGDARKDESYFKATQGGNAFASDLVQQISDLNKGKYLHDDIKVEHNYDFCVGVAGY
PEKHMESPSLNTDLKRLKQKVDAGADYVVTQMFFDNNKYFEFVKKAREIGITVPIIPGIK
PLAVKRHLQILPQVFKIDLPEDLIDAVEGCKDNKAVRQVGIEFAIQQSKELKEAGVPFLH
YYSMGKSDNIHAIASKLF
>A0A837DGZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium carotovorum subsp. carotovorum|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWESGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTTMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A5B8RAY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured organism|TrEMBL
MTQPKNLDTRPAGLHLEVVPPVLRESEAGVEAALEKVATINEAVGLDAVNIPEIREESSK
SDKGERKRPFEPRMEPRVLARRIRDELGIESMINRVVVHLTREEQADWFRETWEEYGVRQ
FVLVGGEKSGVDYPGPSVPEANEMIRKAIAEPGLRVGNICIPTRDGEADRMRRKMATGVD
FFTTQIIYHAHEFTDLVDALVDNGLPETPPELLLTMCPVKGPRNIRFLHWLGVSISPELE
EWLVGDGEGVTDRSIEHIERTWQEISAHRARRAPGLPVGVSLAPIGKIPHETTIRLARAF
TGGVRARATA
>A0A5N3PBH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga brassicacearum|TrEMBL
MSPLTLRPSRQASCPIKVSFEFFPPKTPEMEATLWSSIERLAPLQPQFVSVTYGAGGSTR
ERTHATVSRLVRETHLNPAAHLTCVDATKEEVDGVISAYWEAGVRHVVALRGDPVGGLGT
AYAPHPQGYRRTCDLVRGIKAVGDFEVSVSAYPEKHPEAASLEADIDELQAKVDCGADRA
ITQFFFDNEHYFRYLDRVRARGINIPIVPGIVPVQNFKQTANFAAKTGASIPAWLAARFD
GLDGDVETRKLIAAAVAAEQVIDLVDRGVNEFHFYTMNRADLVYAICRLLGLRGQADKVA
A
>A0A2P4UGB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura rubteroloni|TrEMBL
MPSARTDRAPTIRELLAAGGRTFSFEFFPPKTEPGMRNLWRAIRDLESLGPSFVSVTYGA
GGGTRDTTVDIVERIATETTLTPVAHFTAVNHTLAELRHLVGRLADAGVRNVLALRGDPP
GDPLGPWVKHPEGLEYAGELVRLIRSYGDFCVGVAAFPYKHPRSPDIESDTRYFVQKCRA
GADYAITQMFFRADDYFALRDRVAAAGGDVPIIPCVMPVTQLSTIERSEQLSGAPFPPEL
RARFEAVAHDPEAVRRLGVEHAAEMCRTLLDQEAPGIHFVTFNRSTATREVYELLEADRY
AASGSAPPITA
>A0A0D6EIJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporidiobolus salmonicolor|TrEMBL
MTTVPELRQQHHSQKVSERIASLAPDAPYYTFEVFPPKTDIGLANLVDRIDRMSSLSPTW
MHVTWGAGGSTQERSLELAGASQGMGLDTCLHLTCTNMQEGVLERTLKRAKELGVVNLLA
LRGDPPRGEEYWVASSDAFQHATDLVRYIRKEYGSTFCIGVAGYPEGHADSPDKLADIDY
LYEKQQAGADFVVTQLFYDVDIFMNWYKACRERGITIPILPGIMPIQNYLSFRRMTNLCG
TYIPADIMSDLERIQHDDAAVKDYGVQLSVKMMRALYEQGLRGFHLCTLNLEKSVTRVLE
QLGWVESGATRVKPVLQKTIAPNGAVLPKVVNSLRASGTNSSGTNVASTDLARKDSPTSW
DEFPNGRFGDARSPAYGDMDGYGVGLKLPFPFTPLGSAGAGTDEFERGRVQPAEALRTWG
TPTTLADVSRIFSSYLRGTLACNPWSEEPLRAETNSISASLIEMNDTRHWWTVGSQPAVD
GAPSADAVHGFGPKGGYVYQKAFVEFFLTKEELDELERRSAADEKSRRERGEGDDGLIKW
FAGNNRGELRSNMGKGEVNAVTWGVFGGKEIVTTTLIEEMSFKAWNEEAFAIWNEWSFLY
PAQSPARSFIRKIADERWLVSVVHHDYKDTDALWRWLLEQKKEDETR
>A0A1G0XM04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_45_14|TrEMBL
MQKITEILDKKKTTLSFEFFPPKTVEGSVKLFSIIGELKTLKPSFVSVTYGAGGSTREMT
HDLVVRIQKELGICVVSHLTCVSATTEDIRNVLKSYHDSGIRNIMALRGDPPQGKNYFEV
TEGGFIYAGELVGFIKKNFPDMGVGVAGFPEGHPSTPNRLMEIEHLKAKVDAGADYICTQ
LFFDNHDFYDFRERCELAGIKVPIIAGIMPVTSVKNMQRMADLAAGSRFPAGLLKGLKRA
GDKEDYVRKVGIHWAAEQIRDLLHEGVAGIHFYTLNKSEDVLEICMSAGIHSSESL
>A0A258Q760|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilales bacterium 28-44-11|TrEMBL
MEGIANLREARLALAKYKPEFFSVTFGAGGSTRDRTMDTVFEIQAEGYAAAPHISCISSS
KEEICELLNAYQAKGIKRLVTLRGDVPSGEVSAGDFKYANELVTFIRQETGDWFHIEVAA
YPEFHPESPSAAKDIINFKRKVDAGANSAITQYFYNADAYYRFIETCEHEGIHVPIVPGV
MPIYNYTQLARFSGVCGAEIPRWLRLRLEAYGDDLASLRAYGADVVTEMCSRLIDSGVKS
MHFYTLNQAGTISKIIQNLHQ
>A0A7W6RIM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium mongolense|TrEMBL
MALNTGDRRNIGISFEFFPPKSEEMEGQLWKTVAELQDWDPDFVSVTYGAGGTTKAPTLT
AVTRFLNETPLATASHLTCVGATKEETHQVIDHFRKAGVKHFVALRGDAPGGAGVPYQPH
PGGYANAAELVAGLREIADFEISVSAYPEKHPESRDVAADIDMLKRKADNGADRALTQFF
FDNDNFERYLEKVRTAGVKIPIVPGIMPIQNLTQLKRFASACGTVIPAFLDERFAGLDDK
VEERAKIAVDVAVEQIEDLVRRGLDEFHLYTMNRSPLVSAVLTNLGLRREGAKRAAGAAA
>A0A7J5E8S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melioribacteraceae bacterium|TrEMBL
KYIEDSLLDAEPMNFCIGVAGYPEKHFEAPNLLTDIRYTKAKVDAGASYIVTQMFYENKE
YYKYVELCKQEGINVPIIPGLKILTSQSQIQNLPKNFFIDVPAELAEEARTAKAEHVYEI
GIEWTLKQVEDLLNHNVPAIHFYIMQNSKPIKQLLKKLNR
>A0A848F5R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azohydromonas caseinilytica|TrEMBL
MNKPQRDFALSLEFFPPKTPEGVTKLAAVREQLYPLKPEFCSVTYGAGGSTQSGTLQTVR
SILAEGQEGAPHFSCIGASRESIRAQLAEFKAAGIRRIVALRGDLPSGFGAGALGEFRYA
SDLVRFIREETGSHFSIEVAAYPEMHPQARSPRADLLAFATKVEAGADSAITQMFFNADA
YFRFVDEARALGVNIPIVPGIMPITNASGILRFADACGTEMPRWMRLRLESFGDDTPSIK
AFGLDVITALCERLLDAGVPALHFYTMNQSATVLELCRRLGR
>A0A562LHJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium daqingense|TrEMBL
MTDVTTPATAEGHLRRPAISFEFFPPKTEEMERNLWDTINRLAPLDPKFVSVTYGAGGST
RERTHSTIARILRETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPAGGIG
TPYSSHPDGYQSSAELVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLQAKVDAGAT
RAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARAFVTRAGTTVPDWFAAK
FDGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISHLLGIRAKSAQ
KAA
>A0A0T1TAI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Root1310|TrEMBL
MTTLRDTLGRGTPSFSFEFFPPKTAKGERTLWEAIRRIEPLAPAFVSVTYGAGGSSRERT
VEVTKRIATDTTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGDPNAPWT
RHPDGFTHAHELVSLIKESGDFSVGVAAFPERHPRSPDWDSEIRHFVAKCRAGADYAITQ
MFFRVEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIARFAALSGAAFPEDLAHRLDAVR
DEPAEGHRIGVEHATAMAERLLAEGAPGLHYITLNRSTATLEIHRNTANSRSTRHALAAQ
H
>A0A1L9PI06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus versicolor CBS 583.65|TrEMBL
MHVSEKLSQNEAAGKIGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDVTWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQERVDGALQAAYKAGCTNILALRGDPPREKET
WEATDGGFRYAKDLVKYIREKYGNHFCIGVGGYPEGADDNSDVDLLIDHLKEKVDAGSTF
VVTQMFYDTDNFIQWVQKCRAKGITVPIIPGIMPIQTYAAFIRRANWTKTRIPPDWLETL
EPVKNDDAAVKQIGKSLIAEMCRRLIDSGIKHLHFYTMNLAQSTQLVLEDLQLMPTAETP
VPRPLPWRPSLGLNRREEDVRPIFWRNRNSSYIARTQIWDEFPNGRWTDSRSPAFGELDS
YGVGIKGTNEQNIKLWGEPKSIRDLADVFVRFLEGQLDRLPWSDTPITPETNAIKDPLVE
LNKRGFLTINSQPAVNGVKSSHPIYGWGPKNGFVYQKAYLELLIPAYLIDELISRIEANE
DLTYHAVTKHGELRTNTRDSPNALTWGIFAGREVVQPTIVETVSFLAWKDEAYQLGEDWA
KCHDSASPSRKLLQGVMDSWYLVNIVNNDFHNTYDLFKLFKDLNVEDIDVEFAGEKPEPK
VQNGTTNGTTNGTTNGATPEQSVKN
>A0A1G9I667|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. YR511|TrEMBL
MSPDINPFDPGAPLEPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSVITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGIHV
MAYRQEEYVAEIVHESGVLKGRRPWKHETLPEDAMVAERLEHIREGKEENQQQMAEAAAH
HPH
>A0A1F8RHN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_64_32|TrEMBL
MDAINVGDNPTAKVRMSPLAMSVLLQRELGLEIIMHYTTRDRNALAIHSDMIGAHTLGIR
SILCLRGDPPSIGGYNDIVGVWDISAVGLMRFLKLLNEGVDWTGKPISGQADFFIGASCD
PNADPLEPQLRLMRRKAEAGAHFFVTQNVFDEKVLERFLDKAQRFHLPIIVGVLPLHNSR
HAEFLHTQVPGMCVPDAVRERMRRAGDEGGPAEGQAMARDFLAFCREKCAGVYLVPSFGR
FDLVAELVKEVRDV
>F9Q2Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis SK313|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A7I8JGD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirodela intermedia|TrEMBL
MKVIEKIRAAEQENGKTLFSFEYFPPKTAEGVENLFERMDRMVSHNPSFCDITWGAGGST
ADLTLDIANRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKSSGIQNVLALRGDPPHGQD
KFVQVSGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDMIKGEQGVTAEDYQNDLVYL
KKKVDAGADIIVTQLFYDTDIFLKFVNDCREIGISCPIVPGIMPINNYKGFLRMTGFCKT
KIPPEVTAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALGILMN
LGLIEESKISRSLPWRRPTNVFRVKEDVRPIFWANRPRSYIARTGGWEQYPRGRWGDSGN
PSYGALTDYQFMRPRSRDKKLQEEWGIPIKSIEDINERFSSYCLGKLSSSPWSELDSLQP
ETKIINEQLESINLKGSSPSTASQRSTGRNPIRWGGPGGYVYQKAYLEFFCSKEKLDALV
EKSKAASSLTYIAVNKDGQSVSNVGPVEVNAIIQPTVVDPASFAVWKDEAFEIWTQVWAS
LFPDGDPSKQLLEQVQSSYFLVSLVDNDYVNGDLFAVFKDI
>A0A2T9YVF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium simulii|TrEMBL
MNALQSGFFASHTPSTPFFSLEFSPPKTAQGEKNLENRLERIALWKPLFGSVTFRIPGTT
ITQSIDFASKIKRDYGIEPLLHLTCVNMTLGKINCALRRAKEKGIINILALKGDYPDSEA
LASAGLTETNLVKPEFTFASQLVEYIKTNPEFKDVFNVGVVGHPEGYFRKDSTDLKVCSI
DQIYNNKNISDGIDLQEIRFLKTKVDKGANFVISQAFYSSDKFLNWYNTCRVYGISVPII
PSFFPIQTYKSFELVTKLNSLYVPQDLLDKVKPATNDKIKLEEMGVDLAVKQISEIREST
DVIGFHISTLNLEKNVKKILEGTGFIQNENIPF
>A0A844I423|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter adhaerens|TrEMBL
MTMMSERQAFIRPEEEAAARFRELVRSASIEATPRQILTTEHLPDLLPVGTSVYVPFLPK
GQFSDTLAASCRLLELGMQPVPHVPARMAQSRGQMEDWLAQLHESGVDRLLLIAGDSDAV
AGPFPDTLAVLESGLLAHFQFHGIGVAAHPDGHPMADRATLAQALSVKREYARTTATRLW
VVTQFTFDAEVVIDWLQGLGNILEEVPVYIGMPGPTRVKTLIAYAAMCGVGASARMLLRR
PGSARMLGAWKPDDMVQALVQYCLENPETLLRGIHLFPFGGLRQSAQWIREHSGSVDDKR
EAVS
>A0A7S2Y5H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amphiprora paludosa|TrEMBL
GGGSLGSTAVQSMAVASHTQKFLGVDALLHVTAQGVGAQDLKRHLHQAKLSGIQNLLVLR
GDPPRGKRSWLPGDVSGGDFPRAIDLVKFIRQEYGDYFGLAVAGHPEGHPSSASIQQEIQ
HLKDKVEAGADFVVTQFVYDADKLLQYVRLCRDEGISCPIIPGIMPIQSYNSFLRMTEYC
SVSIPDHILDRLSPVRNDDQAVKEIGVEVAVDMCRRILKESNGEVEGVHFYTLNLERSVT
NVLLKMGALDWTGSEQGDAENLVAEQRRNRSPSLSEIESRSGRVLPWRPSAMQGRSQTEE
VRPINWANRPKSYVQRTEDWDEFPNGRWGDATSPAFGEWSTLGHFMGPA
>A0A2T4GDA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium culmorum|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRAQDKWEAAD
GGFQYARDLVKHIRNTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATFIVTQM
FYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDALEPVKN
DDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELHWAPSADRPLQHAL
PWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDAYGIGL
TGSNEANRKKWGEPKAIQDIAELFVSYLNNKIESLPWSESPLTTEADEIRDDLIELNKRG
LLTINSQPAVNGVKSSHPIHGWGPDNGYVYQKSYLELLVHPGVFDKMISRIENHPDLTYY
AVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDWAHCYD
ISSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVNDLTTPATPLSEPVANGAV
DTEPIANGTAVTAAAN
>A0A1E7JKZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces abyssalis|TrEMBL
MAIGISATRTDSTTTVRELLATGKPSYSFEFFAPKTEKGERSLWNALRRIEAVSPTFVSV
TYGAGGSSREGTVRNTERIANETTLTPVAHLTAVNHSRAELRNVIGQYADAGIRNVLAIR
GDPPGDPMGEWIRHPEGLTYASELVELIKESGDFCVGVAAFPEMHPRSDDWDTDVRHFAA
KCRAGADYAITQMFFRAEDYLRLRDSAVAAGCETPIIPEIIPVTNVKQIETFAQLSNATI
PGELADRLRAVEDDPAAVRSVGIEYATEMCATLMAEDVPGLHFITLNNSTATLEIHQNLG
LHNRP
>A0A2N2A488|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-9|TrEMBL
MKIIDRIQSGLTLSFEVFPPKADKPLEPLHDTLEQLYSLNPDFISCTYGAMGSNKGRNLE
VVRSIQQSGKCEALSHYTCVGNSREDVLSALSDYTEAGVENLLALRGDFPAGVAETKGDF
AHANELIAFIRSQTSRFSLAAACYPEKHLLAESMDSDIDALLKKQDAGADFLMTQLCYSV
ENYLRFIDRARKRGVTLPIVAGVLPLLKKDGLVRMTLSNGCSIPAEVASLVGRYGAEEES
FRAAGHEFTVSLVQRLIQEGANGIHLYTLNRFEDVADLVRDAGIREKSENSR
>A0A7X0D1L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium wenxiniae|TrEMBL
MAILNLFKNRRADEKTERASFGALLDGYSIEVMPRTAAKIENFREFLPAGMRVYIAHIDG
TPIEDMVATAKRLTDDGYAVMPHVPARLIRDKAMLEDWISRYVNEAGVSQALLLAGGLSS
PRGELESSLQLLETGLFGRYGFKRLNVAGHPEGNKDIDKDGTTRLVDRALKFKQAYSENS
DAEMAIVTQFAFDARSIIRWTERIAEAGVTLPIHLGVAGPTKLQTLIKLAISCGVGPSLS
VLQRRAMDLSKLLVPYEPDEFLTEIANYKATHPQSLIDEIHVFPLGGIRASADWVNERVL
KGKVASR
>A0A165EG67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei|TrEMBL
MSASALRSLLTSARYEILPTSGIIDRITDHVAPGRTITVTASAGLGLDATLSTAEQLQAL
GYDAVPHIAARMVQGRTELTEIIDRIGHAGIDTIFVPAGDATPPAGGYASALDLLVDLTS
MAPPISRIGVSAYPESHPLIPDDVTVQAMWDKRDYATHIVSNLCFDPGVVSTWLARVRAR
GIELPLILGIPGKVELAKLAKVAAKIGVGESTRFLRKNTGTFTRMARPGGYNPRKFLDRL
SPVLADPYMDVSGLHIYTFNQVKDTEAWRRKQLELLGDPDSSSIVS
>A0A109N307|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peribacillus simplex|TrEMBL
MNFRKELKERMLVGEGAMGTLLYSYGIDQCYEELNCTNPGQIESIHRAYLEAGADILQSN
TYGANFNKLKRHGLEDEVSKINRQGVILAKKAAKGKAYVFGTIGAQRSIRKSDLSMEEIK
RGFREQLYSLLMESPDGILLETFYDLEELETVLEIVKKETELPIIANVSMHELGNLQNGI
HLNEAFQKLEQLGADVVGVNCRLGPHHMIRALEEVSLPKHASIAIYPNASLPDYVDGRLV
YKAVPEYFGSSALDLRKQGATIIGGCCGTTPLHIQAVKNAVGSLVPVKEKLTKPREIEIM
EISDREGELPLYEKAKTERTILVELDPPKKLGIETFMVGAKALKSAGVDSITLADNSLAS
PRISNEALANLLKDQLNVKPMVHITCRDRNLIGLQSHLMGLQTVGLNEILIITGDPSKIG
DFPGATSVYDLSSFDLISMVKQFNEGLSYSGQSLGQRANFKIAAAFNPNVKYLDKAVQRM
EKKIACGAHSFLTQPIYSVQQMEEVHEATKHLETPIFIGIMPLTSTRNAEFIHNEIPGIK
LPDNVRRAMALAGDDPVKARIEGVSIARELVDAARDKFKGIYLITPFLRYEMTAELTKYI
RKADSKQTSEVAVHE
>A0A836BWF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edaphochlamys debaryana|TrEMBL
MKLIDKINQKVKEGKTFFSFEFFPPRTEEGVENLFERLERMVTYAPVFCDITWGAGGSTA
DVTLDIAARMQNQICVETMMHLTCTNMQIEKLESALKEVKKMGVRNILALRGDPPKGQDK
FEAVEGGFSCALDLVKKEHGDYFGICVAGYPEAHPDGIVDDPEQMQKNYWADIAYLKEKV
EAGGDLIITQLFYDVERFLQFVKDCRSVGINCPILPGIMPIMTYGGFKRMTGFCKTKVPA
ELDAALEAIKDNDEAVKNFGIDLGVKMCRQLLDAGTPGVHLYTLNLERSALAILERLGMV
DPAKIPRPLPWRHVPAGTSRSVEGVRPVFWSNRPKAYLKRTQDWDSYPSGRWGNSRSPAY
GTLSDYQFMRRHTSSDARKEKARAAWGATLSGVEDVQEVFVKYVKGEVTMLPWSEMEGGC
AAETAAIKEPLTQLNASGFLTINSQPRINGLPSTDATHGWGGANGYVYGKAYVEFFCSPA
SWASLRARLDAAPSVSYLATTAAGPTEGNMEADGVNALTWGVFPGKEVIQPTVVCPASFA
VWKDEAFELWLSEWANLYEEGSESRAVLQAIHDTWVLVSVVDNDYVAGDLFKTLLA
>A0A5K1PGR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus stratosphericus|TrEMBL
MGLLQDLENRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSIEEIKR
SFREQLYILLNEEPDGLLLETYYDIEEAKAVLQIARKETTLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPLLENSHLSVYPNSSLPSLEAGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHISAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKDAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMAKAGEDKAKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKESNIHVNYH
>A0A7U4BNE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii TYTH-1|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGK
ARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVKTGKEFTPEIARFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAKLLLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKQT
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A842LZA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Archaeoglobi archaeon|TrEMBL
MKVFSNLMKEIKEGKFVFTGELEPEKETNLENTIKSAQELKGYVTACNVTDNPNSMAYVS
SLVASYMIQEKAGMEAIYQLRCTDRNAAALTSDLLGACVLGIRNVLALTGDHIGLGDYAK
AKPVYDLDSAQLTYMIRRMVDEGVDLYGNEIHGEVRLHVGVAANPNCEPLEAEVLKLGRK
VEAGAEFVQTQVIYDIERVREFFELLREHGIKIPVLIGIFPLKSYGVAKFFDEHVAGVHV
PEELMERITRAKDEPDKKKRKEKILEINLDYFIPFLKELRKTEAAGCHIMAVGYPEIIPP
LTEAVR
>A0A7H1VDT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas titanicae|TrEMBL
MSSHEHPLGISFEFFPPSTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTREVVR
AVGESGINTAPHLSCIGSEKAQLRDLLAQYREEGIESLVALRGDMPSGMGSIGELRYANE
LVEFIRTETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLEGGAPGLHFYTLNQAAPVLKIVDNLAG
>A0A1I6AX61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacillus psychrotolerans|TrEMBL
MSLLEKLQTSMLTADGAMGTLLYSYGIDYCNEELNIQKPEIIEKIHQDYIAAGADIIQTN
TYGANAIKLARYGLENHVKEINEAAIQIAKRAAASGNQFVLGTIGGIRGIRKSDATLQEI
IHSLDQQAIQLLAGDPDGLLLETYYDFEELKTTVTYLRTLTDIPIIAQVSMHDPGILQNG
LPLNDALHELETIGANIVGVNCRLGPHHTIQAFEGVKLPEKAFLSAYPNASLLDIDEGRI
VYESDAEYFGKAALYLRDAGVRLIGGCCGTTPKHIEAVKRHIGHLTPITNKVVETRKPII
IQDAKPTNTQALHEKAKTERTIIVELDTPRHLDTTIFMEGAEKLYATGIDAVTMADNSLA
SPRVSNMAMGSMLKHQKNIRPLAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKI
GDFPGATSVYDVSSLELIQLIKQLNEGISFSGKSLRKKANFSVAAAFNPNVRVLDRAVKR
LEKKIECGADYFITQPVYSKEKIHEIYEATKHLSTPIFIGIMPLTNSRNSEFLHNEVPGI
KLSEEVLERMRLCGEDRERATAEGIQISKELIDTAAELFNGIYIITPFFRYDMSLELIHY
IQEADREKERGFSYVQTSN
>A0A8G2EUE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobaculum litoreum DSM 18839|TrEMBL
MSDTPRVSFEFFPPKDEDGEAKLWHTVARLEPYCPSFVSVTYGAGGSTRERTSRIVKRLA
RESSLTPAAHLTCVGATREEVDDIVREWQAAGIKHIVALRGDAPADAEKYEPHPGGYANA
AELTEGLRRIGDFEISVGAYPDVHPDSPTPAADLDNLKRKIDAGATRAITQYFFDADTFL
RFRDVCDKAGITVPVVPGILPVTNFKTVVRFSNACGAIVPAWMAELFDGLDEDPETRQLV
AATTASDLCMKLMEEGVEDFHFYTLNRPQLTAAICRRLGLRPEMEAAA
>A0A444CNM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensete ventricosum|TrEMBL
MKVIDKIRGAAAEGDGRTVFSFEFFPPKTEEGVENLFERMDRMVAHNPNFCDITWGAGGS
TADLTLDIANRMQNMICVETMMHLTCTNMPVEKIDHALDNIKTNGIQNVLALRGDPPHGQ
DKFVQVAGGFACALDLVWLLSTY
>A0A809HLN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. P2ACOL2|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLDAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGSGKPDMYATDLVTLLKDVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAA
>A0A4S4KIT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hermanssonia centrifuga|TrEMBL
MKISKKIEQAEKENRTWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
DLTSELVKTCQGLIGIETCMHLTCTNMPAEKVDAALKDAKANGCRNVLALRGDPPLGKDE
WEAVEGGFVHGVDLVKHIRKNHGDYFDIAVAGFPQQQLLPAEELAQEIQWLKEKIDAGAN
FIFTQMFYDVDLFIAWVNTVRAAGIKVPIVPGIAPIQTWNGFMKSTTLSRTTIPQSLLDQ
LEPHKNNDEKVRELGTKLVADMCRRILDEDIGIRGLHFYTMNLEKGTRMLLEELKLVPRI
EVVKPLPWRQSLTPNRRTENIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQSKEEAYKLWGHPTSTFDITTLFARFCLGQVPALPWSDTAPASETSVISSQLA
KLNELGFLTINSQPAVDGVRSDDKVHGWGPSNGYVYQKAYLEFFVSPELLAALLPYIERD
PNITYYVINKRGDLRTNNHSDGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGRQ
WAKYYEPDSLSRKFIDELMENQLLMNVVHNDFKRPDAIFEPFFKAGSQLAAAQQTPAAAT
NGTPNGNANGHAR
>A0A545ZTS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. rho-1.1|TrEMBL
MTSTPDTGRSDVSISFEFFPPKTPDMEGQLWAAITELTEWQPEFVSVTYGAGGSTKAPTL
NTVRRMIAETPLPTASHLTCVSATREDTHRVVDELRAAGVRHFVALRGDPPGGIGTAYQP
HPGGYENAAALVAGLRDIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDVFETYMERVRAAGIAIPVLPGIMPIQNLTQLKRFAGMCGTSIPSYLDERFAGLDD
KPEERAKVAADVAAEQIEDLVRRGHREFHLYTMNRAPLVGAVLERLGFKRTKIAEAAGAA
A
>A0A0D4DV39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lydicus|TrEMBL
MALGTASTRTDRARTVRDLLASGKKSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNVIGQYADAGIRNMLALR
GDPPGDPMGEWVRHPQGLDYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDRAAVRSIGIEYATELCARLMAEDIPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A4E0RAH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium yuanmingense|TrEMBL
MSGAMTDLTTPATADRQDRHLKRAAISFEFFPPKTEEMERNLWETINRLAPLEPKFVSVT
YGAGGSTRERTHSTITRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRG
DPVGGIGTPYSSHPEGYQSSAELVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKA
KVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTV
PDWFAAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLG
IRAKSAQKAA
>A0A386X429|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas alkaliphila|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLMHVRDELAARHPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTTPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
HFVEKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDGDAIAAF
GTDVVSRLCERLLDGGAPGLHFYTLNQAAPVLKIVDNLRG
>A0A2V9XAR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIAREARESASREVLIAGSIGPLGLGVQSRHPAPEEIQDIFNEQALALEERGVDFYILE
TFSYIEELLIAIEAIRSFSGLPIVAQLTYSEEGTTYGDVRPTNAAMQLKNKNVQVIGANC
TLGPQALLPILQELAAVDGVRVSAMPNAGFPKREGDRIVYPKSSPEYFALFAREAAAHGV
RILGGCCGTTPEHIRAMAEAVKLLRPAKTHPAGPAVQAVAKPVPVAERDPESKFWKNLQA
KKFTVCVEIDPPKGLSLERIYEQVDRVMASKKVDAIDINSGAMARVGMDALIVAGALEAR
GVETVPHLTTRDQNIIGLQAALLGAWTVGGVRNVLAITGDPPSVGDYPETSGVYEVDSVG
LVKVLHRLNQGTDWAGKTLGGATNFTIGVAVNPVADDLENEIERFQAKVEAGAHFAMTQP
LFDPQHWHDFLKELGGKPPIPILIGIWPLNSYKQALRLNNEVPGIVIPEPLLKSMEAAGA
AARERGFEVARNMLA
>A0A8G0TGY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella putrefaciens|TrEMBL
MAFHHAQHSQSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQQETDLVAAPHLTLVDASDEELLELAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAADLVRLLRSVADFDISVAAYPEVHPDASNAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPNWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>A0A523D5U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTTGSSDKPQPSEERSFEALLARGAVIFDGAMGTELYRRGIFINRCFDELNLSEPDLVRE
VHRSYLQAGADVIETNSFGANRFKLEPHGFGSQVQEINRRAAELAREVSDGVCLVAGAIG
PLGLRIEPWGPTSMEEAEEAFLRQTEALLEGGVDLFVLETFSDLNEIQQAIKAVHRQCGL
PIVAQMTLQEDGNSLYGTQPEIFTERLEDWGADVIGCNCSVGPQVMLDTLERMSRVTKKP
LSAQPNAGMPRNVEGRNIYLASPEYIGSYARRFVRVGARVVGGCCGTTPEHIRAIQRMVR
SNHIARPSQSGQGAKQAVTAPAEVQPVPREKKSGLAGAIAAGKFVVCAEIRPPRGVDVKE
ALAQAQALKEKGVDAVFIPDGQRASAQMGPTWLAVLIEREVGVETLLHYICRDRNLLGMQ
ADLLGASAAGLHNLMLITGQPPRSGDYPDATGVFDVDAIGLTNVVNRLNHGLDIGDNPIG
KPTAFHIGVHLTPGAKDLGYEIRRFEFKVQAGAEFAATPPVFDVDLLKDCLKRISHTRIP
VLAGLVPLQSRRHAEFLSNEVPGCRMPEAILERMRVAQEAGKAVQEGDAIAREILDEVRP
LVDGIYWGGPFDRLQSLIQVK
>A0A7W0SMF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MIPAGKGRLRTALHSGRFAVTAEIGPPRGADAGAITNKAELLRDWVDAANITDNQGSHTR
LASWAGSILALRNGVEPVMQLTTRDRNRIALQSDLISADAVGIPNVLMLSGDHPSFGDHP
DAMPVFDLDSVQLIWTARLMRDQGRLLSGKPVKPAPHWLIGAVENPFAPPLRFRAQRMGK
KVAAGAEFIQTQFVFDLDIFGRWMREVTDLGLEQRCGVIAGVGPIRTVRAMEFMQSKVPG
IHIPDHVVRRLRGVASDRVAAQGMALCVETIEKLRETTGVAGVHVMAFGQEQVVPELLER
AGIPPRTASTATESQDIGTGRDDNAG
>A0A7Y3DXT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MSRFQQAIRSGRLALSAELLPDPGQEPARELERARRLADRFDAVIVNPAAGEPATPPPAA
MAALLLREGIDPVCVLNCRDRNRIALYSELLGLRAAGVRSVVLERGEDTGLPKHAKPVYD
VDVRELSAIAQELNEDEAAPGQEFLVGARLPLIDPAADWNDQPLAALASAGTEVLLTRPC
LDGKRTRDMMARFVAERLTWRFSVVVTLAVPVSSEEARRLADSVPGSRVPASLFEELDTA
ADPRTEGIGLGARLIRETAELPGVSGINLLCLDEVEPLLSAVAGAGIQSSS
>A0A845TR81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacteraceae bacterium|TrEMBL
MTSPDFSIEFFPPKTAEGADKLRATRARMAVLNPKYFSVTFGAGGSTQQGTLDTVLDIRS
EGHQAAPHISCLGSSRARLREILAEYRSHGIERLVALRGDLPSGYGAMDAASGEFRYANE
LVEFIRAESGDWFHVEVGAYPEMHPQARSPSDDMQHFVRKVQAGADAAITQYFYNADAYF
RFVDSARKHGVQVPIVAGVMPITNYTQLMRFSDMCGAEIPRWIRLALASYGDDSESIRAF
GLDVVTAMCERLLVGGAPGLHFYSLNQAAPTMAICQRLDASLV
>A0A3M2D3B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKPFRELLEEDGIHVFDGAIGTRLYEKGVYINRNFDELCLSAPELVLEVHQEYVKAGAEI
IETNTYGATRHKLQLFSLENKLREINIAAARIARKAAGDKVYVAGAIGPLGLRIEPYGPT
SFDEAKDMFKEQVEALLEGGVDLFVIETFSDLSEIKQAIRAVKEVCDLPIVAQMTIQTDG
KTVFGADAEMIARRLEEYGADVIGLNCGVGPTHILSAIEKMRPVTDKKLSAQPNAGLPRD
IQGRQFYMCSPEYMSKFAKRFIQAGASFIGGCCGTTPKHIKMICDVVRALSPRTQKFYVK
REETVRVEDLTPPDVQVVPPEERSNWARKIALGEFVTSVEVLPPKGIDASKTLDAIRLLV
DAGVDAVNIPDGPRAQTRMSALATAVLVQQKVGIEAILHYCCRDRNLLGMMSDLLGAAAL
GVNNLLIITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGKPTRFSIGV
GVNPGAINIDEEIRRFEWKVEAGAEYAITQPVYDTKQLRDFLKRIEHCRIPIVAGIFPLV
SYRNAEFMHNEVPGVNVTPEILERMRKASDISKEAAREEGLKIARECLLEIRDLIQGVQV
SAPFGNVKYALQVFEVLDEFKERLKANPKAEPAKGET
>A0A8G2BTN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides chinchillae|TrEMBL
MKVIDLIKSSKSTAFSFEILPPLKGNSIQKVYNVIDKLREFNPKYINITSHHSESIYKTL
SDGNLQKVNIRKRPGSVAIASAIQYKYGITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDIKTLDADQKTNQYHEHATDLQKQVNNFNKGIAIDGSAFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYAFVERCRKEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEAFACELRKCKNDEEAKEVGVEWCIQQCKDLIAHGVPSLHFY
TMMASDSVQKIAKEIY
>A0A7Y2VKJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MSRFQQAIRSGRLALSAELLPDPGREPARELERARRLADRFDAVIVNPAAGEPATPPPAA
MAALLLREGIDPVCVLNCRDRNRIALYSELLGLRAAGVRSVVLERGEDTGLPKHAKPVYD
VDVRELSAIAQELNEDEAAPGQEFLVGARLPLIDPAADWNDQPLAALASAGTEVLLTRPC
LDGERTRDMMARFVAERLTWRFSVVVTLAVPVSSEEARRLADSVPGSRVPASLFEELDTA
ADPRTEGIGLGARLIRETAELPGVSGINLLCLDEVEPLLSAVAGAGIQSSS
>A0A1Q2HLH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sedimentisphaera cyanobacteriorum|TrEMBL
MPIKDLVQKGVVIGDGAFGTMLYQKGVFINACFEELNLTKPDLIKAIHSEYAAAGCDFLE
TNTYAANSIKLAGFGLADKVEEINMRGAELARECAGESLVAGSVGSASTASDAAESDNYL
DDVRRAYAEQIAALDKAGVDLLVFETFADVNAMLAALDAASDNTDRKIIATLRPALNWRE
RGAERIKSALARVAERENVFACGFNCGMGPSDMLELLDETRDLTDKPFCIQPNAGLPQNV
DGRSIYMCTPEYMAEYSKRMYEKGADIIGGCCGTTPAHISEIAKAVKGVSKADQQARVYS
VKASGQDEEQEKPVVPLKERSLVGRKLANGEFLTTVEITPPRSISLETTAEKAEKCRDAG
VDAINIPDGPRASFRQSALATAVRIKQAGISPILHVCSRDKNIISLQSDMLAAASMGIND
MLFVTGDPPKVGDYPDATGVFDVDAIGMARMARMLNSSRDIAGSEVPDATKMTIGVGVNP
GANDFEREIERYKMKVEAGAEYCVTQPVFDLDTFFRFTDAIKGFEIPVIAGIWPFTSKRN
AEFMANEVPGIVVPKELIERMGKADNKEDAIKTGIEIARESIDAIRDKIAGLAVSAPFGK
VDLAISVIQ
>A0A1Q7EKF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium 13_1_40CM_69_27|TrEMBL
MGTLLYARGVPMDACFDLLNLSNPRLVQSVHAEYVAAGADCIETNTFGANRFKLAVHGQS
GDVRTINLRGVKLARDVRESMGRDVLVLGSMGPLGKYLTPLGSVTLEEARATFREQAEAL
LEGGVDALIVETFSDLTEITLAIEAIRSVTDLPIVAQMAFTDEGVTFMGRSPAEVARTLR
ALGVQALGANCSVGSSILYEVLEHMLPEAGGVPLSIQPNAGLPSRIGERLMYLSSPAYMA
DYAGRMLEVGARIVGGCCGTTPGHIAAMRTVLDRKTTVRRYQDRPAVSARAREAVETPGL
RTTAAPTLLGRKLESGEFIVTVELDPPRGHTVEKLIQGAKLLKERGVEIVDINDGSLGRV
RMSVLPTAILVREAAGLDINMHFTCRDRNLMGIQADLLGAHALGIRNILAMTGDPPRTGD
YVNATAVFDVDAIGLVEILRRMNEGQDATGNSIGEPTAFCVGAALDPSVQDPAREIERFQ
RKVEAGARWVQTQPVYDLAVLDRFLERAGGSSVPVLVGVLPLHSFRHAEFLHNEVPGITI
PDHVRAQLREAGEGALRVGVEMAQRLVQQIRGRYGGVYLMPSFGRFEVVAEVLDALR
>A0A7V3VIS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MNKREALASWMKESVILADGAMGTLLHLRGIPRNRCLEEANLSQADLVFALHREYVHAGA
QILTTNTFKANRLGLRVFDLEGRLEEINARGVEIARRAAHGAPVWVGASIGPLKVMLKPY
GDMEESEAREICREQVAALASAEPDLFILETQQSALEACFFIDACREVAPEIPILASLTF
NREGRTFFGDTPVEGCRRLARQGADVVGINCSVGPADTLPLVEEICQSVGHPLVVMPNAG
YPTEVDGQIHYLSSPEYVANYIKRYVDLGVNIVGGCCGTTPETIRAVARIIRNRPPVKRQ
GSPKGWVVVENAPAAAPPPQEGGFFARLRSGFAVTCEINPPKGPDAREAVETARLLKQAG
ASAVDIADNPMARVRVSSMALAHFVQQETGLPTILHMTCRDRNLLALQSELLGASLLGVE
GILALSGDPTAHGDFPSATSVNDVNVVGLVKIIASLNRGLDFSDHAIGTPTQFAVGVGVN
LTARDPDKEIAKLRERLDAGAVFAMSQPVFDLEPVQRFLDRAKGLPVVILPGVLPIASLK
QALYLANEVPGMTVPRTVMDRFERLERREDQMALGVELAQELLRGLKGFAAGAYLTSGGR
KMSVLVDVLAALH
>A0A7X3Z5X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRRSELAAFLRERPRVGDGALGTALYAGGIASRRSFEDLNRSDPDRVRAVHTAHLAAGAE
VISTNTFGANPWKLGRHGLASEVATINAAGAQVARSAVRPGSLVFGSVGPSGEVVGPFDE
EKAPEFAAGFREQIVALVESGVDAVLIETFTSLAEARLALSAAREVAPDIGVIVLMTFSE
QATTLFGVAAEQAAGTLERDGADAVGSNCGVGPDTTLAALERMRDAVSLPLVAQPNAGIP
ERTEGRFLYPSSPDYVAHYAKRYLRLGVSLIGGCCGTGAEHIGAVAGVVRAASAGARADR
VKAPARPATAAPAEDAPAEIPAVPVPERSGLARCLAEGRFAVSVEMDPPRGAEPGKFLAR
VGDLADAGIRFVNVADGPRATARMSAIAFAALLERSGEVESILHYQCRDRNLIGIQSDLL
GAHALGIRNLLAVTGDPPKLGDYPHATPVFDVDSIGLVRILRGLNHGLDLAGNPLGAALP
FHIGVGANPAAADVEGEMGKFEKKVQAGAQYCLTQPVYETRLLERFVKDVRGYGIPILAG
VLPLVSTRNPRYSTKQLPG
>A0A7V6DG84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTTPRVHRRFADHIVVADGAMGSELLARLPATAQLDLAPLHHPREVEAIHLAYLQAGAEV
IETATFAASRPRLARLGCGDLTEAVNEAGVKLAREAREVSGVDCLVAGAIGPLAGVLDMD
EPAGRAAIAQAHAEQAAILAGRGADLLVLETFFRLDELELAIEAVQGVTSLPIVALLTFA
DESHPEGIEEQAAAVRALLQRDVLAAGVNCTPGPSGALAVLQAVGAAPGRLAAMPNAGRL
VRRDGRLLSPPATPSYLARFAAEAAAAGAILVGGCCGTGPEHIAAMAAAVRGVHPAHRRR
VRVAVAAPPEPARPAPRRPPSPLADKLAAGRFVRVVQLDPPKGTNSDRLVAAVATMARHP
AVDAVDINSNPLARLRMDSLWLAAELQRATGVEAIAHVTPRDASLMGLQSQLLGAWRGGV
RSLLAITGDPSQLGDYPGVHDVYHVDIFELVRAIARMAEGVDCAGNPIGEPPEFCIGVAV
NPAADDLDHEIGRMHRKVEAGAHFIMSQVFFAWDVWERFLDRCGGRLPLPALVGIWPLPS
LKLALRLHYEVPGIVVPDELLAALQAAGSGAARVGLERALELLAGAPGRASGVYLIAPFK
NPEEVLALLPPEATDPR
>A0A2V7UZ48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSSKASPDAVKPFLERLAEGVVVCDGAMGTMLYARGVFLNRCFDELNLSNPNLVQSVHRE
YLEAGADVIETNTFGAHRFKLGPHGLEAQVRKINREGARLAREAAGGAALVAGSIGPVGK
PLAPIGNIPFEDAKAAYREQVEGLLEGGVDVLMIETMPSLDQARAAHEAVRELTADLPVV
VSLTFNEEGTTLYGDTPEDAVRTLEGWGVQAVGANCSQGPQAMLLTIQRMAAVATTAKLS
AMPNAGAPALVDGRYVYLCTPEYMASYARRFIAAGASLVGGCCGTTPAHIKNLVRSVRML
QPSREAVTVLPPSRAREAPVAVPREEKSALARKLGKKFVVSVELDPPKGVDPGQVLERAH
YCKEKEVDAINVADGPRASARMSAQALCVLVQNKVEIDTILHYTCRDRNLLGMQSDLLGA
YALGLRNILAITGDPPKLGDYPDATAVYDVDSIGLIRIMDHLNHGCDLAGNLIGPALGIH
IGCGADPSKPDMEKEVRRLEQKVEAGAEYIMTQPIYDPRTLERFFSMIKHINAEFLHNEV
PGMRIPDEIRERMKKAGSGEKAQAEGVSIAQEATLAARDGAHGVYIMPPFNKVDLAVRVI
DVLH
>A0A2V9TWW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MASDFLSRLSKSPILCDGAMGTLLYANGIFINRSYDELNLSQPEMIHSVHQGYLQAGAEI
IETNTFGANSFRLGRYSLADKVHEINRAGARLAREAAKSFDVWVAGSVGPLGIRIEPLGK
TSFEEARAAFREQIAALAEGGVDLLILETFGYVEELHQAMLAARDVNPKLPVVASVTVDE
ESNCLDGSDPETFAAKLADWGADVIGCNCSIGPVAMLDAIERVRAVTTMPLAAQPNAGMP
RSVEGRNIYLCSPEYMASYAKKFVAAGVRLVGGCCGTTPEHIRMMKSALRVGEARAARVQ
TAKPHPSPAAGPTEPIELRSNLGRKLIAGEFVTMVEIVPPKGTDIRKEVEGARFLKSVGV
DGINIPDSPRASARISNQALSLIVQREVGIEAILHYTCRDRNVLGIQSDLLGAAAMGIRN
LICITGDPPKMGNYPDATAVFDVDAIGLVNIVHNLNRGLDIGGNAIGAGTGFVIGVGANP
GLPNIDEEIRRFEYKVEAGAEYAVTQPVFDLALLENFLRRIEHCRIPVIAGIWPLVSVRN
AEFMKNELRVSVPDSIVERMAKAPTPEAARQEGVAIAREMLIAVRDLVQGAQISAPNGKY
AAAVDVLEALGAGSRERQSSVFSPQSSA
>A0A355FA16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKVTEHLARADRPLVSFEIIPPLRGGDVKGLLGLIDELARFRPPFIDITSHAAEVIYEET
SQGLQRRVKRKRPGTLGVCALLQNKYQIDAVPHILCRGFTREETEDFLIELKYLGIDNVL
AVRGDDSGYQKPLQHGRSANSYASDLVAQIDAMNHGRYLEEELLDAQPSSFCIGVGGYPE
KHFEAANLKLDVRHTKEKIDAGAHYVVTQMFFHNEHYFRYVDACREQGITVPIIPGLKIL
TSAKQLTTIPRNFYVEIPDGLADEILAAKPEHIADIGVEWTLRQCEELLARGVPALHFYV
MQSANAVKKLIGRLQV
>A0A2E8EDJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRFIRDIYAEKQASGRPVISVEFFPPKTPKGDETLFDRTLPALQAVSPDFYSVTYGAGGS
TRDKTLAVADRIQREHHTTTMAHLTCVSTSKADIERYLQEARDMGIRNILALRGDPPQDG
GELARLEGGFEYSYQLVRCIKAMGDFSIGTAGFPESHIACKEGKQVDWQRLKAKIDRGAD
FVLTQLFFDNDDYFTFRDYLVETLGVRVPITPGVLPILNTQQIERFTEVCGATLPTDLRA
KLEAYGDDADAVAEFGIEFATRQCEALLAGGAPGLHLYSLNKAHAATQIIQNLGPRA
>A0A448QS91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus equuli|TrEMBL
MLWDSIHRLKALKPKFVSVTYGANSGERTRTHSIVKNIQQETGILAAPHLTGIDASPDEL
RAIAQDYWDNGIRNIVALRGDEPVGYTKKPFYAADLVRLLKEVADFDISVAAYPEVHPEA
KSTQADLIYLKQKLKPAPIAQSLNFL
>A0A2V7Z479|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKVTEHLANADHPLISFEIIPPLRGGDVKGLLNLIEDLCKYRPPFIDITSHAAEVMYDET
PAGIQRRVKRKRPGTLGVCALIQNKYHIDAVPHILCQGFTREETEDFLIELRYLGIDNVL
AVRGD
>A0A3M0YLU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium J149|TrEMBL
MTKLENAIASKEFIITAEVTPPKGGNPERMLEVARLLKDRVHGVNITDGSRAVLRMSSIA
SCVLLQREGIEPICQMTGRDRNSIALQADLMGAYSLGIRNILALTGDPLKAGDHPQAKAV
FELESVRLLKLIGQLNEGFDLNNKTLTDGNLNLFAGAAVDPQLKSWSGLQRRFEQKIKAG
AKFFQSQLITDFDKLDRFMNEIAKGCDRPILAGIFLLKSAKNARFINKNVPGVEIPEHII
NRLEKAENPLLEGMTIAAEQIKDAQQICQGVHLMAVKREDLIPQILDLAKIHH
>A0A2V7WVF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
QSDLLGAYALGLRNILAITGDPPKLGDYPDATAVYDVDSIGLIRIMDHLNHGRDLAGNAI
GPPLAIHIGCGADPSKPDLEKEVRRLEEKVKAGAEYVMTPPVYDPRTVETFLGMIRHLRV
PVLIGILPLYSHKNAEFLHNEVPGMTIPEDIRERMRAAGSGEGAQAEGVRIAQEALLAVR
DLVQGAYVMPPFNKVDLAVRVIEVLR
>A0A1H6DHP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea solani|TrEMBL
MLASGGRSFSFEFFPPKTDEGERQLWRAIRELESLRPTFVSVTYGAGGSTRDRTVDIVER
IAHDTTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVRGDPPGDPGAEWVRHPEGV
LYAEDLVRLIRQSGDFCVGVAAFPYKHPRSPSIESDTDYFVRKCRAGADYAITQMFFQAD
DYLRLRDRVAAQGCETPIIPCIMPVTQMSTIARSEQLSGAPFPPDVAARFEAVKDDPAAV
RRLGIDHGAELCQRLLDEGAPGIHFITFNRSSASREVYQRLERVALPA
>A0A2K9DZT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hominis|TrEMBL
MMSHEPRATAPIVDDVSPRSARTVPFSFEIYPPRTAEGLPALHETIRVLAATGPRFISVT
FGAGGSTTDRSLAVLTHILRETPVPPVAHLTCVGSSYAEATTVIREFLDAGITRFLALRG
DPPAGVAEDEVALGDLESAAQLVQLIDRVQAERSPYREQEIPGVPGAAQVAAGERVEIAV
AAFPNGHPRSRHRFEDIDALLAKQAAGATSAITQLFFRPADYLDFVSRARAAGVVIPILP
GIMPITSPARLRRVLELTGDPRPDDLAVALEAATDAAAQRAVGIAHAADLARAVLDGGAP
GIHLYAFNNHDTVLAVLRAAGLIPEETTP
>A0A424J6V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium TMED51|TrEMBL
MATDTAADTLPDLKSGSNLEKVLAAGHFAVTGELGPPKHMDTSVVDRKIGLLKGVVDAAN
VTDNQTGIVRLSSIATGIYMAQHGLEPVIQMTCRDRNRLAMQSDLMGAYIHGIRNVLCLS
GDHQSFGNHPGAKNVQDIDSMQLIRMLQEMRDKNQFQCGDEIKGGGPKLFIGGAGSPFSE
PISFRPLRIAKKMAAGVDFIQTQMIFDMDIFRQFMRRLVDLGVTEKVHILAGIGPLKSSP
MARFLNENIPGIVIPEDLLKRMDGAVQGISEDNKEARRDAWRAEGQDICIEQIKELQQME
GVSGVHIMAIEWEAAIRQIVERAGLLPRPIV
>A0A857GG42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas meridiana|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAARNPRFFSVTYGAGGSTQARTRDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMASIGELRYANE
LVEFIRNETGDHFDIAVAAYPESHPQAPSLDKDVENFARKMNAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GTDVVTRLCERLLDGGAPGLHFYTLNQAAPVLKVVDNLS
>A0A7V5LJG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldithrix abyssi|TrEMBL
DPVLEAKDDEEVLEIGVDWAYNQVTELIEKKVPAIHFYIMQNSKPIRLLMKKLEF
>A0A1U6HG57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium mathurense|TrEMBL
MTAAIRPADAPLFGVQPGDISVSFEFFPPKTEKMETQLWEAITQLAPLSPSFVSVTYGAG
GSTRERTHATVSRIIRETDLVPAAHLTCVAASKAQIDEIVDRYWEAGVRHIVALRGDPPP
ADGGRFVPHPEGYASAADLVAGIKARHGFDISVAAYPEIHPDATSAEADLDNLKRKLDAG
ASRAITQFFFSTDAYFRFLDKALAAGITAPILPGIMPVTSFSAIRRMSGNTEIPAWLEAM
FEGLDDRPGPRALVAAVAAADLCKRLYDGGVRDFHFYTLNRAEQAYAICQLLGLRPKEIG
>A0A1T2A0I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioclava sp. F28-4|TrEMBL
MTTPKVSFEFFPPKTLDASFRLWETAQVLAPLKPEFTSVTYGAGGTTRKLTHEAVGTIHK
NYGLNVAAHLTCVEATKAETMEIVDAYAEVGVTEIVALRGDPPQGAKHFTPHPEGFASSV
ELIEALAEDGRFTIRAGAYPEPHPDAADNMADVRWLKRKVEAGATSAITQFFFEPETFFR
FRDACEKEGIDAKIIPGILPIQSWKGAKKFAQSCGTSIPAWVEEAFEAAIRDGREHLLAT
ALCTELCDKLIEGGVEDLHFYTLNRPGLTRDVCHALGVTPDTVLEKVA
>A0A1B3MXH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. RAC03|TrEMBL
MTLNDPAAPLYADLAGDCQVSFEFFPPKSEKMEAQLWSAIETLTPLAPKFVSVTYGAGGS
TRERTHNTVARIAKETPLAAAAHLTCVGASKDEIGEIADAYWEAGVRHIVALRGDPPEVG
GAFEPHPQGYKGAADLVEGLIKRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGAIR
AITQFFFTPDAYFRFLDKVLAAGITADIVPGIMPVSNFAATQRMAAMCNTQVPSWMARLF
EGLDDHPASRQLVSATIAAELCQKLYAGGVRDFHFYTLNRSELSFAICHLLGLRAKATAD
A
>A0A2G2IBV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colwellia sp|TrEMBL
MNKQSELRARYNDINRGVYFIGTTPPKNDTPLEAIETIAEKLLERVSDIDFDGLIVYDIQ
DENSRIKKPRPFPFKLTHDTRLYSSLLNKKSGRPVITYKSVVHSNGSDFDQWANEAWQKY
GVRDIVLVGSPSKNNNISLPLADAYKTLVDNEHDFFIGGVTIAERHASKKNEHERLIEKH
KQGCNFFISQAIYNPQATIDMLTRYAIECKKQGLKPQRLILTFSPCGSKKTLEFIEWLGV
NVPEATSLRILHSESPLYESIRICTNSLQQILDAVVPYDLPLGLNIESLTNRKEEIDGSI
LLYKLLRSTMENYLAKKELNQLNKK
>A0A3S3N0Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cinnamomum micranthum f. kanehirae|TrEMBL
MKVIEKLRVASDEDRTIFSFEFLTPRPKEDLEKLMSTIDGMVSHGPSFCDLTWRPGGLEA
DLTLKVSGKMQNEVGVETLLHLAVTGMTMEMIDHALDTAKAKGINNILALKGDPVKGKDP
AQDPLQCALDLVKYIRAKHGDYFGIAVAGYPEAHPCMKPEGSEVATEEGYQSDLEYLKKK
VDAGADLIITQLFFDTDAFLKFVGDCRQIGISCPIIPGILAISTHRNLAYMTKMCKPKIP
KEMKDALELVKDDEEALMKYGIQMGTEMCRKILAHGIKTLHFYTINKERAALAILKNLGL
VSDNENTKSLEGGVQNHTGSNGTIH
>A0A7K4JH90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geococcyx californianus|TrEMBL
MVNETQHICSTSSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6A6NK81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hevea brasiliensis|TrEMBL
MATTLALLSLVIQVLKAILGFLLCPILLHYPQKIISLCSSVIFRSEAHPDMIRSDGVATP
ENYQKDLEYLKRKVDAGADLIITQLFYDTDIFPELVNDCRQIGINCPIVPGIMPINNYKG
FLRMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEVCKKILAHGIKTLHLYTLNM
EKSAPAILMNLGLIDESKITRSLPWRRPTNVFRAKEDVRPIFWANRPKSYISRTLSWEQY
PHGHGRILAIHPIFMRARARDKKLHDEWATPLNSIEDILEKFKKHCLGKLKSSPWSELDG
LQPETKIINEQLGKINLKGFLTINSQPAVNGERSDSPSVGWRGPGGYVYQKAYLEFFCST
DKLQVLVDKCKSFPLITYMAVNKGGTLVSNVGTNDVNVVTWGVFPAKQISNQLLLIPPAS
MCGRMRLLKSGLEVGLPCTQRMIHLENCLKRYLVTILSAERLLFGQLGR
>A0A7V5S705|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Fraserbacteria bacterium|TrEMBL
MPESNLQRALEAKKFVVTAECGPPKSADRRVIEEKAKLLKDWVDAANVTDNQTAVTRMSS
LAACAILKSFGLDPVFQITCRDRNRIALQSDILGAYALGIRNVLCLTGDHQSFGNHPQAK
GVFDLDSVHLIETVKKMRDEGRFLSGDELTGERPAMFIGAVENPFAPPYEFRALRLKKKV
EAGAQFIQTQIVYNIQRFREFIARVGDLGLLDKVYIIAGVSPIKTPGAAKYMRDNVPGLD
VPNEIVSRMEAAGKGIEDKQARAEAWRQEGIKICVELIQQLKEIQGVAGVHIMAIEWEEA
VPEIVQKSGLKS
>A0A235B4K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paludifilum halophilum|TrEMBL
MVKTGLKETLAESLLIGDGAMSTYLYQQGIPVGVSAEELSLSRPEWIEDIHRQYYRAGAR
LIETNTFGANRERLSRYGLEGKVTRINRESVALARRAVGNKAYVTGAIGSINAGRVPNYS
KTEYRGMYEEQATAQLYAEVDGMVLETFQDLEEVLLALETIRPLTRVPIFAHVSMIEVGR
TRDGYTLTEAFQALKEKGADGVGLNCRLGPLELQRALEKTVVPEGVILSVFPNAGRLGMN
NGEFRYKSTPEYFGERALSLREQGVRLIGGCCGTTPEHIRAVARQLEGLSPFPRNNPEQP
LADSEKGRPRVEVRTRPTVVEKVKRSQTVIVEFDSPKELEISDYLHGAEQLNRAGADAVT
LADNSMATTRMSNMALGSILKNRTQAEPLIHITCRDRNLIGQQSHLMGLHALGIDQILVV
TGDPTRIGDLPGSSSIYDVNSFDLIRMVKQLNEGISFSGRPMKQKARFVVGAAFNPNVSR
LDSAVRRLEKKVEAGADFIMTQPVYDPEAIRRIAEAVQPVGIPVFLGIMPLTGHRNALFL
HNELPGVKIPGSVMKRMEGLKGPKAREVGVSLAKELLDEAVRHFNGIYLITPFSYWEMTA
ELVRYLRQKEKHLQAAIH
>A0A1J4S522|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium CG1_02_58_13|TrEMBL
MNFLELLSTQTILADGAMGTMLHGRGIGFDKCFDELNLTNPASVADIHREYIEAGAQLVI
TNTFGANRFKLTKHGLEDQVADINRAGVELAKRAVSASFKEVLVAGDVGPLGVRIAPYGR
VQPEAARAAFAEQINALCSAGADLIVIETMSDLYEIKEAIRAARDVGAGLAPAQGQGRPQ
GSPLPVVASVTFTRDDRTILGDDPAKVARILAEAGADVIGVNCSGGPAQLLRILKAMRAA
APAGRFWVKPNAGWPEQVGGRIMYPADAKYFGEYALSFREAGASVVGGCCGTTPAHIASM
RRALASAGAPAPLTVTPLPVEEEALEGAQPPSELAQKLSAGKFVISIEMDPPRGLSTHKL
VAGASLLHEAGADVINVADSPMARMRMSAWAVCQVVQRQVGAETTLHFPTRGRSLLRVQG
DLLAAHALGIRNVFVVMGDPTAIGDYPEAMDNYDLVPSGLIKLIKQGFNVGVDHSGASIG
QPTNFFVGAALNLVPPDPDTEIKNLQRKLKAGADFFLTQPIYRAEDGEGFLAKNELKHGA
LNRPVLVGILPLVSAKHANFLNHEVPGISIPEEAIARMEAAGEDAAKVGVELAVELIEKV
KPWAQGIYIMPQFHRFDLVAEIVERVK
>A0A7X9SWE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium xerosis|TrEMBL
MSDFPPPAVGRQVPVRHALTLPSPGPVPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFA
SVTYGAGGSSRDRTLRIAERVSREPLTTLVHLTLVGHTVPELREILRAYLDRGLTNLLVL
RGDPPGDPLGDWTPMEDGLSYASELIEFIRSEEEFADFEIGIASFPEGHFRAPDLESDTR
YTLAKLRAGAEYSITQMFFDVDHYLRLRDRLAAADPEHGSKPIIPGLMPITSMRSVRRQL
ELSGSVLPAALDERLTRAAAGDEEANRDEIRKVGIEVTTEMAERLISEGVPGIHFMTLNF
ARATQEVLHNLGMAPAWGTGQDMLRGGF
>A0A0B9AIZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium linens|TrEMBL
MSQATLRTLLSTARYEILPTAGIVERVGEYVAPGREITVTASTGLTLEATLSTAEQLQAL
GFRAVPHIAARMIHGRPELTEIVDRLAEAAIDRIFVPAGDATPPAGGYVGAHDLLVDLSS
MAAPFQHIGVSAYPESHPLIPDDVTVQAMWDKRDYATHLVSNLCFDPTTVASWLARVRAR
GIELPLMLGIAGKVELAKLARVATKIGVGESTRFLRKNTATFTRMAKPGGYNPRKFLDRL
APALDDQDMGVAGLHIYTFNQIKDTEVWRRKQLAALGGAEAVSSVW
>A0A1G1L404|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica bacterium RIFCSPLOWO2_02_FULL_45_16|TrEMBL
MTFCDKIKANKFIVTSEIGPPKGIDIKEALEDADLIKGKVDAINVTDLQSSVMRLGSLAV
CHLLKDRSIEPIFQIACRDRNRLALQSDLLSAAALGIENVLALTGDYTTLGDHPEAKPVF
DLGSIELLDVIKTLQEGKDMKGNALKGAPKFCVGAVVNPGADPLEPEIIKMEKKISSGAL
FFQTQAVYDIELFKRFLDAAKHLKTTILAGIVLLKSAGMAKYMNKNVAGVFVPDSLIKEM
EETKDKSAQSIEIAARLIKDLKPLCQGIHIMPIGWDRKVPLVLSAAEL
>A0A2R7SU54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. HMWF010|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPAAPHLSCVGDSKAELRELLTLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VSFIRAETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADCYFY
FVDRVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTDSIQAYG
EQVITEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A3D0H887|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacteraceae bacterium|TrEMBL
MNTTTPSKLEKIIAAGHLAVTSECGPPRDGRPGVVEHKANLIRNHVDAINVTDNQTAVVR
QCSLAACIRLKLMGLEPVLQMVTRDRNRIAIQSDLLGATSFGIHNILCLTGDHQRFGDHP
SSANVFDMDSTRLIQTVKLMRDEGRLLSGFEMQEGRPQMFIGAAENPFADPFEIRVLRLA
KKAAAGV
>F6CTN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinomonas posidonica (strain CECT 7376 / NCIMB 14433 / IVIA-Po-181)|TrEMBL
MKSELARKFQDIRRGIYFIGTTPPRSSIQEEQLQEISQKLLHRLEDIEVDGLIVYDIQDE
TSRIDKPRPFPFMETHDPRAWSKRLHLASEKPVVTYKSVSSRSAEEFSGWLTEAWEDYGI
RDLVLVGSPSSEGDIKLPLPKAYQTLASSPHNFNLGGVTIAERHAKKGDEHLRLIKKVSA
GCDFFISQAVYNPQATADLISRYARSCKEEGKNPTRIILTFTPCGSAKTLDFMEWLGISV
PEATKHRILDSETPLEESIKICRNALEQIIEVALPLGVPLGLNIESLTNRKEEIDASIQL
YRLLKATLDLKLAEQALI
>A0A357Y3Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp|TrEMBL
MQRVSVELVPRDEATLREALALAQQYQEQIDVINIPDLLRLPLRSWEGAAIAQEQFPQVM
PHIRAMDIDLDAELPMKAYLREHNIREVLVIQGDPPQDMSHVVYPTTSTDVIRKFHDEMP
EVKVYAGIDQYRSSMAEERYRIRRKVQAGAAGFFTQPFYDLRFLEMYADMLDGLEVYWGV
SPVMTQRSQSYWERKNHVVFPRSFEPTLDWSVELTREVMAFADKNDASLYVMPIKTNLAA
YLAGIFA
>C0QKS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforapulum autotrophicum (strain ATCC 43914 / DSM 3382 / VKM B-1955 / HRM2)|TrEMBL
MKSGSKLERILNAGHFAFTGEVGPPRGANVEALKEKVAHLKGVVDMANITDNQTAMVRMS
SWAASLICMEGGVEPNFQMVCRDRNRLAMQSDILGAYAHGIHNMLCLSGDHQQFGDHPQS
KGVFDLDSMQLIGMVKKMRDEGKFLGGADIDVPPKIFIGAAANPFAEPFEWRVHRLAKKV
TAGADFIQTQCVFNMERIREWIRQANDMGLTDKVFILPGITPMKSVGMAKYMKNKVPGMD
VPDEIIKRLQGVDKKKVADEGIKIACEQIQEFKEMKGVAGVHLMAIEWEHKVPEIAERAG
VLPRPEV
>A0A1D2U5D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp. SCN 67-35|TrEMBL
MHLPVSFEFFPPKTPEGVGKLRDVRQQLYALQPEFCSVTYGAGGSTQAGTFATVREVLAE
GVPAASHFSCVGATRETVRAQLAELQAMGVKRLVALRGDLPSGYGMGGEFQYASDLVAFI
RAETGRHFHIEVAAYPEMHPQARSPEADLKAFAAKVRAGADSAITQYFFNADAYFRFVDE
ARRAGLAVPVVPGIMPILGSTQLLRFSDACGAEVPRWLRLRLQGFGDDVASLRAFGLDVV
TRLCEQLVAGGAPALHFYTMNQSAATLQLCRRLGRAEQA
>A0A2U1YK83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. TSO5|TrEMBL
MTAPTSALPSISFEFFPPKSEKMEQSLWQSIRRLAPLSPSFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGRYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDAYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPKKLAETFEGLDD
DPETRQLVAATVAAEQCQALQAQGVNDFHFYTLNRSDLTIAICRMLGVKAKAAPAAAVAG
>A0A139STL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cephaloticoccus capnophilus|TrEMBL
MISDSTISRLFSEKSRPLRSLEFFPPKEELDVLALKKTASELVKIAADFASVTYGAGGGT
RQRTAEVSQLLRGELGCPIMPHLTCVGHSREELHALADEIHASGFRNIMTLRGDLPKSAV
QSGTGQKPLEDDAPRYASDLVALLKARHSDFCLGVAAYPEKHPQAASLESDIAHLKAKID
AGADFAVTQLFFDNAVYFRFVEKCRAAGISVPIVPGIMPALSLAQVRRFTAMCEVVLPEK
LAAQLAAAGEDNPDEVAHIGTQWTIAQVRELLASGAPGYHLYTLNRARSAVELCAALAEA
>A0A562INW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter roseus|TrEMBL
MSRALSVRDPVFRASLKQVFQAMGYEVIPFKKTEESVLANVPREVPLTVTASPAKGQDAT
VELAVSLVGHGYTVAPHLSAQQVRDRAHLADVVARCREAGITDVFVVGGDRADTPTQFTD
ALSLLRALHELDHGFTEIGIGGHPEGHPEVGPDVLFQALEDKASMATHIKTQIVFDPKVI
LAWARELKRRRIDLPVHVGVPGAVTRQKLLRVSGGLGIGESAKFLKKQQNLFWRFFVPGG
YSPDTIIRGLAPHIGKPDNAIAGFHVFTFNDLEPTEAWRTRTLQNLS
>A0A2X5NUX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tatumella ptyseos|TrEMBL
MSFFHANQHEALNQSLSELNGRINVSFEFFPPRTQDMEDILWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDANRDELRSIAQDYWDNGSAILWRCGVT
SRMVSVNRICMLLIW
>M4BR52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyaloperonospora arabidopsidis (strain Emoy2)|TrEMBL
MAEQDIKQALDQAKDAGIRNILALRGDPVRGASSFNECDRGFSHGVDLVRYIRKHYGNQF
CIAVAGYPEGHAESSHEDLEAGVQYLKKKVDAGADFVISQLFYDVSVFLDFVQACRAAGI
TVPIIPGIMPIQNYGGFERMTSFCKTFVPDDVREALEPIKDNDEAVKDYGVQLGITMSQQ
LIDAGVPGLHFYTLNLERSVRRILEGLSSLSRHVPRRELPWETSMLSKRASESVRPIYWS
NRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESHFAPSNTWTPVERRSMWGDAPASKE
DICNVFVRYVRGEISSLPWCDAALHDETSTVQQELANANAAGFLTINSQPRVNGAVSDDP
MFGWGGPGGRVYQKAYVECFVSPENMKTIITNAAKKPSVQYHAVNLNGHSYSNASKSAVA
VTWGVFPNKEIQQPTIVDSSSFLVWKDEAFALWLKLWASLYEPSSPSFKLLHEIHDTYFL
VSVVDNDFMNGHIWDLFEASVSPVTSP
>A0A2X4R2T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus haemolyticus|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWNSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIESYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPE
>A0A1S8PXU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium beijerinckii|TrEMBL
MIKELLKNDILICDGAMGTYYSEVTGNDVSYCEFGNLNDKETIKRIHKEYIEAGAKLIRT
NTFSANTYDLGVSLETLMDIIKSGINLAKEVTRNTSVLIGASIGPIKTDNLDEFSNEVLE
EYKYIVDCFLKNGIDIFIFETFSNYNYLKKISEYIKYKNIDSFILTQFAVKPDGFTRDGL
SAAKLIKEVRNTKYIDAFGFNCGSGPAHILEMVKKINIENEIVSVLPNAGYPEIIHERTV
YPNNPLYFAKKVNEIRSFGVSIIGGCCGTNPSYIKQLTQIVNENSKVVNANTKAEPKVKS
FEKKAKNTFKDKLENGEFVVAIELSAPIDTDISRIIDGAKICKENNIDLVTVPDSPMSKV
RADSTIISSKIKREIGIEAMPHVCCRDKNTNAIRSSLIGSHIENIRNILAITGDPISDAS
KVETKSVFNLNSFRLIELIESMNEEIFKEDSIYVGGALNLNVLNKEVEYNRMMKKIEKGA
KFFLTQPIYDDNAIEFLKMIKERTNVKILAGLLPVVSYRNAMFLNNELPGVTIPDKYVQM
FSENMSKEEAQEIGVKITVEIGKKLKGIADGLYFITPFNRVNMLIEIIKQINA
>A0A6A5Y195|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aaosphaeria arxii CBS 175.79|TrEMBL
MHISQKLLQARAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPQFIDVTWGAGGRLS
HLTCEMVKVAQSVYGLETCMHLTCTDMERSKLDEALKEAYNSGCTNILALRGDPPREKEK
WEATAGGFRYAKDLVKYIRDKYGNHFDIGVAGYSEGSEDNADVDLLIDHLKEKVDAGATF
IVTQMFYDTDIFLSWVEKVRAKGIDIPIIPGIMPIHTYAAFLRRANWTKCNVPDEWTKAL
EPVKNDDVEVREVGKDLVADMCRRLINAGITHLHFYTMNLAQATRMVLEELEILPDVESP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDARSPAFGELDS
YGIGLKGTNEQNIKLWGTPASIKDISDLFVRYMSGDLESLPWSEQAISKEAESIEQDLIK
LNRRGFLTINSQPAVDGAKSSDSVFGWGPRNGYVYQKAYLEVLVSPEHIAEVITRIERDP
DMTYYAVNKEGDLKTNAPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQDW
ANCHSSVSPARYVIEDLMDTWWLINIVNNDFHVKHGIFPLFDGLQVQDMEKPLHPVGHTN
SDSGSNGVSNGTSAQDGEKSILGNAVDAARSALQNGLNLAN
>A0A7W4VRC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides soli|TrEMBL
MANQQQPGIGDLVRSGGRSFSFEFFPPRDAAGVEQLWQAIRELEPYRPTFVSVTYGAGGS
TRDATVRVTSRIARETSMTAMAHLTCVGHTRAELEGVLDSYSEAGIRNVMVLRGDPQEGP
RAPWTPTAGGLTYAEDLVDLVRARGDFSIGVAAFPEGHPSAESLDHDADVLVAKARAGAE
FAVTQMFFRAEDYFALVDRVRSRGVDLPILPGIMPILNLGNIRRQSELIGTDVPGSVVER
IMAHDGDPVAMRAAGVALAAELCEQLLDGGAPGLHFYTLNRSKATREIFAALNMAV
>A0A1H9WXE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tranquillimonas rosea|TrEMBL
MPDPRISFEFFPPQSLKASFRLWDTVKMLAPLEPTFVSVTYGAGGTTRDLTHEAVTTLGQ
TTGLNVAAHLTCVNASKSETLEIAKSYADADVSEIVALRGDPPKGEGRFTPHPDGFASSV
ELIEALAATGDFKLRVGAYPDPHPDAAHRDADVEWLKRKLDAGAHSAITQFFFESETFLR
FRDKCVRAGITAPVIPGILPIENWTGVRKFASKCGAYIPPWLDHAFDKAGRDDRETDLAT
ALATEMCSDLLAEGIEDLHFYTLNSAQMTRDVIHALGIAPATLLRDVA
>A0A2C8ZW47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinibacterium xinjiangense|TrEMBL
MPTFSFELYPPRSARSEAALYASLPDLVAAGPEFISVTYGANGSSREPSLDVLGHILQGT
NVQAMAHLTCVGSSYAQASELIRQFLDAGVTSFLALRGDPPEGSVEADSFLGDLGSAGEL
VQLIHRVQSEREQFAFLEVPGFPAARRITRGRKVTIAVAAFPNGHPRSRSISQDLDTLLA
KEAAGANLAITQLVFHADDFLGFVDKAREAGVTMRILPGIMPVLSPQRLKRIIELTGEAT
PVELERRLLAASDEAEHHRIGIDHAVALGQEVIAGGATGLHLYTFNQHEPVLAVLRGAGL
LDRQKEHV
>A0A1Y1YJ84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Basidiobolus meristosporus CBS 931.73|TrEMBL
MKVIHKIEQATSENSPFWSFEYFPPKTQQGINNLYDRMERMYTLGPTFIDVTWGAGGSTS
DLTLELCSTAQSVYGLETTMHLTCTNMPKEQIDFALEKAKECGIQNILALRGDPPRGQEV
WTACESGFSNAIDLVRYIRQQYGDYFCISVAGYPEGHLDAPSVQSDLEFLKEKVDAGADY
IVTQLFYDVELFLDWVKQCRALGITCPILPGILPIQNYNGFKRMTTLCKTFVPEEILEAL
EPIKDDDQAVKDYGVQLAIDMCRRMQEEGILGFHFYTLNLERSTRLVLEGLNFVPSQENV
RPLPWSPSLSKKRANETVRPIFWRNRVKSYIARTENWDEFPNGRWGDSRSPAYGDLGVHG
VSLKQSMKEAKQLWKSPRNLDEISQIFADYCNGKVPALPWSDQPLMPESGGITEKLVNIN
RAGYLTINSQPAVNGVKSSHKIYGWGPKNGYVYQKAYLEFFVSPQALDKLVAKINQDPYI
TYYAINRQGDLHTNTQSDEPNAVTWGIFPGKQIVQPTIVEAYSFTVWKDEAFELWAEWAK
VYEPEEATRKCIESIIDDWYLVNVVHNDYQDPDAIFKVFLDH
>A0A0E2NBG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSHC414A00|TrEMBL
MIGRQRDENPSGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A1G0HXD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_42_10|TrEMBL
MNNGLACQISFECFPPKTEAGLANFKTTALALSHYRPDFFSVTFGAGGSTRDGTFCTVNT
LQQLTNMNIVPHLSCIGLTREQLATIVQQYQSMGVKRIVALRGDLPSGMGQSGEFQFASD
LVKLIRDISGDYFHIDVAAYPEIHPQTRNVRDDILNLKRKCEAGADSAITQYFFNPDAYF
YYLDDCARYGIAVPIVPGIMPITQFTKLSRFSNLCGAEIPLWIRKRLESFGDDIDAIYAF
GLEVIYHLCERLIAGGAPGLHFYTLNKSTMITALLEALNVAPISNSLNAATIK
>A0A0R3MXD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium lablabi|TrEMBL
MTDVTPPAFDGHRALHSPKISFEFFPPKTEEMERSLWETINRLAPLAPNFVSVTYGAGGS
TRERTHSTIARILKETSLVPAAHLTCVGAPKGEINDVVARYHEIGVRHIVALRGDPTTGI
GTAYHAHPDGYQSSPDLIAGIKKRYPDIEISVSAYPEKHPESPTIDADIDTLKAKVDAGA
ARAITQVFFDNDLYFRYLDRVRARGIDIPVVPGIMPMHNFKQARSFVTRAGTTVPTWLAD
KFEGLDDDADTRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A5B0WAB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium tropici|TrEMBL
MSSRSESLSDGIRVSFEFFPPKSEEAEQQLWNTVEELSDWEPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLAAGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVGALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKAENGADRALTQF
FFDNDAFERYHDRVRAAGIRIPVVPGIMPIQNLTQLKRFAGACGASIPSWLDDRFDGLDE
NVEERAKVAADVAAEQIQDLIRRGIHEFHLYTMNRSALVSAVLERLGLQRKVNARAGAAA
>A0A447V8A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cedecea lapagei|TrEMBL
MSFFHANQREALNQSLAEVAGHINVSFEFFPPRTSEMEQTLWKSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATPDELRAIAQDYWNNGIRHIVALRGD
LPPDSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLRRKIEAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFRQAKKFADMTNVRIPSWMAQMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAQ
>A0A1Q9SYT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serinicoccus sp. CUA-874|TrEMBL
MASRISVELVPRSAESVRSEMAQVADRLRGVDTVNIPDLLKFDLRSWQATEVARDAARRA
DGTAYRTIPHIRAADVDPDAPLPMADEARRTGELLVVSGDDADYFHSATYPVDAVDVIRR
VRAELPEVTVYAGLDPYRQAMTTEMRYLDRKLAAGANGIFTQPFFDTHLMAAWASVLPEG
IDVWWGATSVTTSGAMGYWRRRNRVVFPAGFDSSMPWQRDFAHRVVDFARERGHHAYLMP
VRAPLLDYLGGVLDG
>A0A4V3WKL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Camellia sinensis var. sinensis|TrEMBL
MKVIEKIRESEGGDKVVFSFEFFPPKTEDGVDNLFERMDRMVIHNPSFCDITWGAGGSTA
DLTLEISNRMQNMVCVETMMHLTCTNMPVDKIDHALDSIRSNGIQNVLALRGDPPHGQDK
FVQVHGGFACALDLVKHIRSKYGDYFGITVAGYPEGHPDVIQSDGLATPEAYQNDLEYLK
RKVDAGADLIITQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFIRMTGFCRTK
IPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKIMANGIKTLHIYTLNMEKSALAILMNL
GLIEETKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWEQYPHGRWGYSHSA
SYGALTDYQFMRPRARDKKLHDEWAVPLKNVEDIHEKFMKYCLGKLRSSPWSELDGLQPE
TKIINEQLVNMNSKGFLTINSQPAVNGANSDSPSVGWGGAGGYVYQKAYVEFFCSRDKLN
ALVEKCSAFPYVTYMAVNKDGIWISKVGQTDVNAVTWGVFPGKEIIQPTVVDPSSFMVWK
DEAFEIWSRGWAQLYPEADPSRNLLEEVQSSYFLVSLVDNDYISGDLFAVFKDF
>A0A8B9DVD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anser cygnoid|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
IELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPQPEPSEVLR
>A0A7Y6CRW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacteriales bacterium|TrEMBL
MALGLESIVPCNRPSVAEIIAAPEPSFSFEFFPPKTEKGELSLWQAIRELEQLRPSFVSI
TYGAGGSSRDRTVAVTARIATDTTLVPMAHLTAVNHSIAELRNVIGHYASVGIRDILALR
GDPPGDPQAEWVRHPDGLDHADELVRLLRQTGSFSVGVAAFPDIHPRSRSFDEEVRYFVG
KCRAGAQYAITQFFFDWEHYTRLRDAVEAQGCYVPIVPGIMPVTNVRQIERMAQLSGAEF
PAELALRLHEVADDPEAVRAIGVEVATELTLRLLAEGAPGAHFITLNKSTATREVWKNLT
GARASV
>A0A7X5VH92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella shirazensis|TrEMBL
MANGLPSTLPGSAPTIRELLASGDRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWVAHPEGLNHAIELVELIRSLGDFCVGVAAFPDKHPEAASLEADAQVLAA
KAQAGADYAITQMFFGADDYFRLVDRATALGCDIPVLPGVMPVTNIKQIQRMAELTGMAL
PKAVTDRLLAVEDEPAAVREVGIEIATELCERLLEGGAPGIHFITLNRSTATRQVFRNLS
SSVVS
>A0A7X6EMB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. BG5|TrEMBL
DIDMLKRKADNGADRALTQFFFDNDNFERYLERVRRAGISIPIVPGIMPIQNLTQLKRFA
GACGAVIPGFLDERFAGFDDKPEERAKVAADVAAEQI
>A0A174M4T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus|TrEMBL
MGIAELINKERKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKDGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVEAGADYVVTQMFYDNRKYVDFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAMKCKDDKEARALGIEWCINQCRELIAYGGPGIHF
YTVGAVDNVKEVATAVY
>A0A2G9ZZU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium CG23_combo_of_CG06-09_8_20_14_all_51_8|TrEMBL
MKSGSTLEKILTAGHFAFTGELGPPRGANLDAIRKKAQPLKGMVDAVNITDNQTAVVRMS
SWAASLFAISEGLEPNFQMVCRDRNRLAMQSDILGAYAHGVRNMLCLSGDHQQFGDHPQS
KGVFDIDSTQLIGMVKNMRDEGKFLNGQEIDGAPKMFIGAAANPFAEPFEWRVYRLAKKI
AAGADFIQTQCVFNMEKMREWIKRANDMGLTEKVYILAGVTPMKSLGMARYMKSKVPGMD
VPDYVIDRIKGVDKSKQADEGIKIACEQIAEFKEMKGVAGVHLMPIEWEHKVPEIAERAG
MLPRPQV
>S3TWX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii NIPH 410|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A653YJ35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. 8AJ|TrEMBL
MTIQSLLAPAAAPTPAEGQAGKYGTVLPVRMQIIPSEGIAARIQAAVPPGAQLTVTCLPR
QGVGPTIRTAIELAYLGFEVVPHLAARSIESREQLAGVVRNCHDAGITEVFAVGGDAGEP
AGPYDSSLPLLEDLAEVSGGTIRAGVAGYPEGHPGHSELHMLDALLEKQHLASSVVTQLC
LSAPRIQWYAQTLRREGVRLPVWAGVPGAVPRAQLIRAALKIGVGPSLTLLNRRGPLGRR
LLQDGRYSSEAIVAELQRGEAVEGIHLYTFNNLAGPAN
>A0A1H9JXP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. YR768|TrEMBL
MTLNDPAAPLYADLAGDCQVSFEFFPPKTEKMEAQLWSAIETLTPLAPKFVSVTYGAGGS
TRERTHNTVARIAKETPLAAAAHLTCVAASKDEIGEIADAYWEAGVRHIVALRGDPPEVG
GKFEPHPDGYTGAADLVEGLMQRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFAPDTYFRFMDKVLAAGISADIVPGIMPVGNFSATQRMAAMCNTDVPSWMARLF
EGLDDHPSARQLVSATIAAELCRKLYEGGVRDFHFYTLNRAEHSYAICHLLGLRPKVAVA
ADVTA
>A0A2T0MUT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea fuscirosea|TrEMBL
MLAAGGRSFSFEFFPPKTDEGARQLWRAIRELESLRPTFVSVTYGAGGSTRDRTVDIVER
IAHDTTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVRGDPPGDPSAEWVRHPEGV
LYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTEYFVRKCQAGADYAITQMFFRAD
DYLRLRDRVAARGCDTPIIPCIMPVTQMSTIARSEQLSGAPFPPDVAARFEAVKDDPAAV
RRLGIDHGAELCQRLLDEGAPGIHFITFNRSSASREVFQRLERIPLSA
>A0A1I0TG60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parageobacillus thermantarcticus|TrEMBL
MGLLEDLQERIVIADGAMGTLLYSHGVDRCFEELNLSKPEDILHIHEAYIAAGAEVIQTN
TYGANYVKLARYGLEDEVPSINRAAVRLAKQAAKNKAYVLGTIGGLRSINKSAVSIDEIK
RTFREQLFVLLNEDVDGLLLETYYDLEELKTVLAIARKETDKPIIAHVTLHEVGVLQDGT
PLAEALAQLEQLGADVVGLNCRLGPYHMIRSLEEVPLPSKAFLSAYPNASLPDYRDGRLV
YETNADYFKETALAFREQGVRLIGGCCGTTPKHIEAMASALTDRTPVKEKVVQQRHISIS
VQTNEQNAAPPLQDIVRKRRSVIVELDPPKKLGIAKFLEGAKALKEANIDALTLADNSLA
TPRISNMALGTIVKEQLGIRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVER
LEKKIQCGAHYFITQPLYSEQKIEEVYEATKHLDTPIYIGIMPLVSARNADFLHHEVPGI
TLSDEIRSRMAACANDPVQSAREGIAIAKSLIDAVFDLFNGIYLITPFLRYEMTVELVRY
IHEKEQAAQEREVLHG
>A0A7Y4RZ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp|TrEMBL
MKNPPVSFEFFPPKTADGMSKLHDARTQLAQFSPEFFSVTFGAGGSTRDRTMDTVLEIQN
EGHQAAPHISCISSSKEEILELLYAYKAQGIKRLVTLRGDIPSGEVSAGDFRYASELVEF
IRANTGDHFHIEVAAYPEFHPEARTPSADLQNLKRKMDAGANSAITQYFYNADAYFQFVM
QCEYLGITMPIVPGIMPIYNITQLARFSSVCGAEIPRWLKLRLEEYGDDMVSLRAFGIDV
VSELCETLIAWGAPSLHFYTLNQAGTISQIIQNISQE
>A0A7K0CTW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces smaragdinus|TrEMBL
MTTLPDLLAAGRPSFSFEFFPPKTAKGEQVLWDAIRRIERLSPTFVSITYGAGGSSRDRT
ISVTRKIAAETTLRPVAHLCAVGHSVAELRHIMGQYADAGIRDVLVLRGDPPGDPQGPWV
PHPQGLHHAADLVSLVRTAGRFSVGVAAFPERHPRSADWDTDIRHFVAKCRAGADYAVTQ
MFFDVEHYLRFRDRVRAAGCETPVIPEIMPATDYRQIARFAELSNATFPDALASGLYEAR
DDARTSHRIGVEHAVAMAERLLAEGAPGLHYITLNRSPAAMEIHRHVLRGQTPGGPPGPP
DDLRRTDALSARH
>A0A5A8F316|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deferribacter autotrophicus|TrEMBL
MKISEILESKKMTLSFEFFPPKKVENEKILFDTIDILKNYNPDFVSVTYGAGGSTKDKTV
DWTIRILKDYNLNVMMHLTCIASSKSDIDVILEILKAEGVENILALRGDIPKDFPVEDIK
KDFNYAYELVKYIREKNGFSIGVAGYPEGHLESESLEKDIEYLKLKVDSGADFVITQLFF
DNNYYFEFLNRAVQVGIDVPIIPGIMPVVNLSQVQRFVEMCGATVPDELVKKLEGRTPDD
MYKIGVEYAVLQCKELIENNVRGLHFYTLNKYNATKEILEGLGYAAE
>A0A1U1DAH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus subsp. abscessus|TrEMBL
MFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSVRRQVELSSSTLPTALEERLL
RAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFMTLNFARATSEVLENLGVRVT
PGTARG
>A0A0N1FT39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium OV450|TrEMBL
MALGTASTRTDRARTVRDLLASGCPSYSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSV
TYGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLAVR
GDPPGDPMGPWVPHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSQDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSAQKAGCETPIIPEVMPVVGIKQLDRLPQLSNAVF
PAAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQRA
>A0A2S9A3P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. MYb64|TrEMBL
MAARALVDDFSLEMTGKDVPGLQEARDTIPAGTKINVTFLGNEDLEMRVAAAKAVRDLGF
VPVPHISARRLRSRAQLEEFLGRLQEVGATDHVFVVGGDPATPDGPYASAFDVIYTGLLL
DYGVREVSIAGYPEGHPDIADDELWRHLENKSAVLAEQGLDAVILSQFAFDTDPVLAWID
QVRARGIASEIRVGTPGPAGVKRLLGFARRFGIGANAMIVKKYGFSLTNLMGTAGPDAFV
SDLSALLAADAETGAVKLHFYTFGGLLATSAWARDFVAARR
>A0A1G1J4C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica bacterium RBG_13_46_9|TrEMBL
MKTPFKEILASDRFIVTAEIGPPKSTDLHEMTEHIDLLKDRVDGLNVTDNQSSVMRYPSL
GTCIIIKERGGEPILQMTCRDRNRMALESDLLFAYSRGIRNVLVLTGDAVAVGDHKEAKA
VFDLDSVQFIKMIRSMEAGRDLGGNELKGEFSFCVGAIVTPEADPIEPQLLKFKKKLAAG
AEFIQTQAIYDLDKFKRFMDIARGFKYQAKILAGIVLLTSAGMAKYMNENVPGVMVPQGF
IDELKSAQKDDRLKKGIEIASRLIRTIREGKLCDGVHIMAIGKEDVVPKILEESGL
>A0A1H0VWX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. cf386|TrEMBL
MTTFSFEFFPPKSEAGERALWSAVRRVEALRPDFVSVTYGAGGSSRDRTIAVTRRIAAET
TLRPVAHLTAVGHSVAELRHIIGSYADVGLRDVLVLRGDPPGDPRGEWTPHPDGFSHAFQ
LVELVRSLGDFTIGVAAFPEGHPRSPDPETDIRHFVAKCKAGADYAVTQMFFHVEDYLRL
RDRVAAAGCDIPIIPEIMPATDARQILRFAELSNAAFPEELAHRLEAARDDPATAYRIGV
DHAVAMSERLLAEGAPGLHYITLNRSTAALDIHRAVQALRSLSAC
>A0A6I1KLT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacteraceae bacterium|TrEMBL
MAIEKTELHKRIESGKPLLLAELSPPKGGDPSPVRAAAKRFAGKVHAVGVSDNRDGVHMS
AIAAASLFIAEGVEPIVHVTTRDRNRIALVSDCLGAQALGIRNLLCTTGTHQTLGPARGA
RNVFDIDSIQLLGMYGGLADDGSLVGEERFEGAGPFCLGTTASPYADPLEMQVIRLAKAV
AAGSKFIITQPVFDVERFESWWSEVTKRGLHEKAAIIAGIQPLANADIAQAYAGRRPIPM
IPDAVLQRISASSDKSVQRAVGLEIALETVQRLSGLKGVRGFEVRGDADADIAIELIEKS
GLGIN
>A0A0U3FCK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CdTB01|TrEMBL
MALGTASTRTDRARTVSDMLAAGKTTYSFEFSAPKTAKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDSDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCATPVIPEVMPVTSVKMLQRLPQLSNARI
PSVLKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A4D7AQK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phreatobacter stygius|TrEMBL
MSTSSYRPSRYVSRSRLKVSFEFFPPKNDEMEATLWESIERLAPLAPSFVSVTYGAGGST
RERTHSTVQRIIKETALKPAAHLTCVAATKDQVDEVIRDYWDAGVRHIVALRGDPAGGLG
TAYASHPGGYEGSPELVAGIRAIGDFEISVSAYPEKHPESASIDTDIEMLKRKVDAGATR
AITQFFFDNEVYLRYLDRARAAGIAIPIVPGIVPVQNFKQTAGFAARTGASVPDWLARRF
EGLENDVATRKLIAAAVAAEQVLDLVDRGVTEFHFYTMNRADLVYAVCHLLGLRPEDEAA
RAAA
>A0A564VY74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia luti|TrEMBL
MLGIENILCLTGDHTKMGDHPQAKPVFDLDSVSLLHTVQLLESGVDLGGNQLVGEPPKFS
KGAVVSPCSDSVDAQLAKMERKVAAGADYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGII
IPKSAGMAKFMNNNVAGIHVPDEMIEELKADKEKTKAGITGVEIAARIIKECKPYCQGVH
IMALGWESKIPALLEQAEI
>A0A2N5ZRS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinivirgaceae bacterium|TrEMBL
MKINKLFLPNKKTFSFEFFPPKDYMTAVRFGINVGQLMSLKPSFVSITYGAGGSSRDNTF
DLVDFFQNELGLTCMAHYTVVGATREKIAYDMRTLQDMGVENVMLLRGDPPKGSKVFPEN
PDGFNYASDLISFVKKNFDFCIGAAAYPEKHIEAASMDDDLDNLKRKVDAGADFLVTQMF
FDNDYYWEFLDNAVQKGIGERIIPGIIPITSYTQIKRFAEISGAKIPEQIEKQLAEVQAD
KQKVYEIGLNIAKKQSLDLLKDGAPGIHVFTLNKSRAAVELYDHIPKIYK
>A0A0M4T415|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter urativorans|TrEMBL
MSKPAFSFEFFPANTDKGHEKLLSIYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALCA
RGGTAIAPHMSCIGDDKSEITGLLDHYKSLGIKRLVALRGDLPSGQVGMGELPFAVDLVK
FIREYAGDHFHIEVAAYPEMHPQARSFVSDIDNLVNKFNAGANAAITQFFYNADSYLYLR
DALESRGIDTTKQKLIAGIMPITNSSNLMRFADSCGADIPRYVRKQLADFGDDGKAIREF
GFDVVYRLGERLIAEGVPAMHFYSMNKVEPNKRLVEALGLTS
>A2XNC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryza sativa subsp. indica|TrEMBL
MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLK
QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNL
GLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLD
QLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWK
DEAFEIWSKGWACLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAFKEI
>A0A1F2WP43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium RBG_16_64_13|TrEMBL
MGAYRDACNSGRFVVSGEIGPPKGTNVESMLHHIDLLKNMVDGLNVTDNQSSVMRLGSLA
VSGEIVRRGGDPVFQTTCRDRNRLGLQSDLLSAAFLGITNVLCLTGDHPSVGDHKQAKGV
FDFDSVHLIQCCHKMNEGFDWAGNELDGGTDFFVGAVVTPEADPLEPQLYKFARKVEAGT
DFFQTQAVYDMDNFQRFMEKTREITAGTNTKMMAGLVVLAGVGMAKYMNRAVPGIFVPDA
LLEELGSVPKEEQLRKGMEIAARHIRFLKENKICDGVHVMAIGKEEIVPEILEMAGLTTS
>G3AY82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida tenuis (strain ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC 10315 / NRRL Y-1498 / VKM Y-70)|TrEMBL
MRISEKLNQAYSSSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYELNPIFIDITWNAGG
RSSSLTNEMVYTAQSALGLETCMHLTCTNMSVSLIDEALERAKKSGCQNILALRGDPPLD
GTESTGDFKYAKDLILYIRKNYGNYFNIGVAAYPEGHPEESDLDLTVKYLKDKCDAGADF
IITQMFYDTDNFIEWCSKVRKIGVDIPIIPGIMPISTYAAFMRRAKWSEIKVPKHFLDVL
EPIKDDDFLVREKGTELVSQMCTKLLESGYVKHLHFYTMNLERSTIMCLENLGLIDQVKS
HDTIGGAILPWRKSLNPSRQKETIRPIFWQNRKHSYISRTSTWDEFPNGRWGDSSSPAFG
DIDLNAADLLRQSPKRAFELWGHPQSLKEFADLTISYLRGQLKSMPWSDGSISEDTSVIA
EDLVKLNQNGFITINSQPPLNATRSNDKVFGWGPKNGYVFQKQYLEFFCHKSVISKLLDQ
VDIFNKSSGDNSRVLTYYVVDKTGELITNTNDEDINAVTWGVFPGEEIVQPTIVERNSFL
AWKDEAYSLITEWVRIFESNLAKDFLKGKEAQVQTSIEFFKSFETDFVLCNIVNNNFTDD
AKELFGVFEGLQFQ
>A0A1Q3HEQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Archangium sp. Cb G35|TrEMBL
MKIRNRLNPSNPCFSFEFFPPKTDEGTANLLKTLEELAPLEPGFVSVTYGAGGSTRDRTV
ELVTRIKRETGIEAMAHITCVGHTPGELRDVLQRLKDAKVENVLVLRGDPPQGQTAFEPV
PGGFRHASELVRFIRDEDFNFSLGGACYPEGHVETASRDDDLRHLKEKVDAGLDFVITQL
FFDNAFYFDFVERARRIGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLGLQLERVKD
QPEALVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRART
>A0A363S3R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. SPM|TrEMBL
MPAGTVQGARAFIDACSLEVSAKAMPALRAEAGRIATGTTISIPYLASEDDEARLAAART
VRELGLQPMPHLSARRIGSRAALEQFITRAAGEAGVEQCLLIAGDLATPAGPFADSTAII
ETGLLEDAGIKVVAVGGHPEGHPVMDAAGRWQALERKCQAIEARGMAPKIITQFAFDADI
VLAWLDALRARGIDHPVLVGVPGPASVTRLLRYAAMCGVGASVSMLARYGISIGRLLGTA
GPDVFVDRLVGGLTEAHGQVSPHLFPFGGIAPSLDWVAQYRRCAGSQQR
>A0A222F3C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labrenzia sp. VG12|TrEMBL
MTDTSNRRSHQAAPSPITASFEFFPPKSDKMAETLWNTVQRLAPLAPSFVSVTYGAGGST
RERTHKTVERILTETDLAPAAHLTCVGASQDEVNEIVRDYWDLGVRHLVALRGDPLEGIG
TRYTPHNNGYPYASDLVAGIKKIANFDISVSGYPEKHPESGSWQSEIDNLKRKVDAGADR
IITQYFFDNDLFDSYLDRIAAAGINIPVIPGILPIHNFEQTMVFSAKCGTSIPQWLARRF
AGLKDDPETRKLVGVSVACEQVMDLVDKGINDFHFYTMNRADLTYAICHMLGMGRQEPEN
LAA
>A0A2A3C8V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3876|TrEMBL
MNQFRFSRRPDIGHKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVRRILTESTLTPAAHMTCVDADRDQVDTVIQEFAEMGVTRFVALRGDPAAGVGT
AYRPHRDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFSQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A2S0WBG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium liangguodongii|TrEMBL
MTERSPSTRLSASAPLDRLDEDPGYPPARRAPVALSFELIPPRHDADTALLDTLIEGLLA
YHPDYVSVTSSRRSDWLEGTAALISRISRTTDLKTIAHLACTAGTREELAGWIRALIDAG
VRGFLALRGDLPEGQTGLPADHLQHATDLIMLIRDVEREQAFRLAAGKLALSVACYPSGH
AESKNADMDLDVLLAKQRLGADFAITQLFFSAQDYLDFVERSRLAGVRIPLIPGIMPMTS
LRRVERMGVLSGITVPECVTRRLAAAGSQQEEYDIGMELTAELTRTILDAGAGGLHIYTH
NNLAVTRDLLGRIGIEEPHHH
>A0A8J5UMZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. raphani|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A7K2E0B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
LKSLDAAIEALPAGSRVSVTASPVKGQDATCEITERLMELGHEAIPHVSARLVDDRARVS
ELAGWFRSAGVSTMFLVGGDVESPGAYSDAASFLRDLLECDHGLSTIGVTAYPHGHPLIA
EEVLHEALHAKQALLAEAGVEGYCSTQMCFDPERIEGWLRGERAAGLTLPVHLGISGVVD
RAKLLTMGARLGVGPSLRYLRKNRAAIMKLMTSPNYDPDHILMALSPSLDDLGVTGLHVF
TFNQVATTVTWQSSHHG
>A0A7C5BU57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MSASNLQLLLDQGHFAVCGEMSPPQGADKASILKKCGYFRDVVDAVNLTDNQTAIVRMSS
VMSSVFALEGGVEPIMQMTCRDRNRLAQQSDILGAYAAGVKNILCLTGDYMSFGNHPDAK
GVFDLDSVQLIHTVADMNAGRFLSGDEMKTPPAMFVGGAANPFGEPFDLRIIRLGKKIAA
GAQFIQTQPVFDIPRFEKWMAAVRDEGYDQQTHILAGVMPVRSVRALIHMRDNVPGSLIA
DEYIKRMDAVKDDKEAGAETGVAMAVEIIKQIREIAGVHGVHIMPVMWESITPRIVGESG
LLPRPGLESPAAEHPEPVEGAAGAPTP
>A0A7C5YL53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MTREQFRERLAQGVLVADGAMGTMLALRGIPQPYALANLTHPDLVRQLHREYYEAGARLI
ETNTYYANRVRLLNLPERGSELPPAYSLLEQFGSPEELVRRINHEAVRLAREAVGEDALV
FGAVGPVGKPLEPMGEVRFEEAEQAFEEQIRALVEAGVDGLILETFIDPHELELAIRVAR
RLAPDLPIIASKGFVEDGETLMEGLPERFAEQVASLDVDAIGGNCIVGPQRMLDIIRMMT
GATDTPISAMPTPGLPQLVRGQVVYDIHPDYFGRYAVRLVEAGATIVGGCCGTTPDHIRA
IAQAVRTAKPKRTAAPTAVRPRERKLKEELPTAEPSRLSQLLGKERVITVELDLPRGLRI
QKVIESARLLKEHGVHLIDISDGARARLRMSVIATSHIIQREAGIEVMMHFACRDRNLLA
IQSDLLGAHALGIRNVLAITGDPAQIGDYPTATSVFDVDAIGLIRILRRFNEGRDLAGNS
IGMYANFTIAAAYNPLASDLELENDRLRRKIDEGAHLIYTQPLFEMPVVERTAELLQRLG
TPWFVGVLPLRSARHAEFMHNEVPGISIPEPILRRISEAPEDSALQVGLEIAQSFVREAA
PYAQGIYIMPPAGSAQIALRVIEALA
>A0A6P1RN31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium odoriferum|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWESGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTTMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A853AKC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora hordei|TrEMBL
MTKVIDRLRPGKTVFSVEFFPPKTDEEERQLWRAIRELEPLDPAYVSVTYGAGGSSRDRT
VRTTGRIASDTTLVAMAHLTGVNHSIAELRHVIGSYAAEGIQNVLAIRGDPPGDPMGEWI
PHPEGITYADELVRLVRECGDFCVGVAAFPHMHPRSPDLESDTKHMVNKLRAGADFSVAQ
MFLEPEHFLRLRDRLAQHGCHQPLLPGIMPITTPKVLGMTTQLSNMTIPDEVSAVLDPLR
DDPAGFREAGLEITTRLCEKLIAEGVPALHFYSLNRSKATREVLANLGLIDGVLKSAA
>A0A6P2FBQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. RA8|TrEMBL
MRLPLSFEFFPPKTPEGVVKLRAVRQQLYARRPEFCSVTYGAGGSTHEGTFGTVREILGE
GVDAACHFSCIGATRTTVREQLKELRTMGVKRLVALRGDLPSGYGMGGEFHYASDLVGFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVRAGADAAITQYFFSPEAYFRFVEE
ARRLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TELCARLASGGAPAIHFYTMNQSVATLALLERLGWEG
>A0A7W6KC45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter zeae|TrEMBL
MKITDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QANGLLEKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHCYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMNTDFKYLKKKVEAGAEFIVTQMFFDNQKYFDFVKKCRENDINIPIIPGLKP
ISTLSQLNVLPKVFHIDLPDELTDALAHAKNNNEAKEIGTEAMIKQCKELIDFGVPVLHF
YTMGRPKQTKKIAKAIF
>A0A838F8I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagales bacterium|TrEMBL
MKVTEYIGQSKGTLVSFEILPPMKGKSIQSIYDTLDPLMEFKPPFINVTYHRSEYIYKRN
PQGLFEKTIIRKRPGTVGICAAIVNRYKVDAVPHIVCGGFTVEETEDALIDLAFLGINNL
LVIRGDPNMSESSFEAEPGGHRNAIDLLKQAVRMNQGIFLQEDITDVVPTDFCIGVAGYP
EKHYEAPNMKMDLKYLKDKVDAGADYIITQMFFDNSKYFEFVKCCRESGITVPILPGIKP
ITNRKHINTLPRMFHVEIPENLANELQAVTTDEAARKVGIEWCIEQCKELIKHNVPLVHF
YTMSNPGPVKAIVSKVF
>A0A7C3ZST6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MVSGSRLERLLREGHFVVCGEMSPPQGADKETIFRKCEYFRNYVDAVNLTDNQTAIVRMS
SAMSSVFALAGGCEPIMQMTCRDRNRLAQQSEILGAYAAGVLNILCLTGDYMKFGNHPDA
KGCFDLDSVQLIYAVSEMNAGRFVCGEEMKSPFGMFIGGAANPFAEPMEMRLIRLGKKIR
AGAHFIQTQPVFDIPRFEKWMSAVRDEGYDQQVFILAGVMPVRSVKALLYMKNEVPGVRI
ADEYIKRMESAKDPKEEGVAMCVEIMKYLMQVPGVRGIHIMPVMWESITPRIVEEAGLLP
RPEPKTSGGEGSDEQA
>A0A7G3ZMQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Torulaspora globosa|TrEMBL
MSIRELYNEKSRPSLSLEFFPPKTETGKRNLLERMVRMSALDPLFITVTWGAGGSTAEKT
LELAAITQRSLNVPVCMHLTCTNTDKTVIDNALRTCQQVGIRNILALRGDPSIEDSVGQE
RVTQEPVDFEHAVDLVRYIRTQYGSYFCIGVAAYPEGHCEGEAEASEQDPLRDLPYLKEK
VDAGADFVITQLFYDVKKFLTFQKLFVDHVSAEVPLIPGLMPINSFLLFNRAAKLSHASI
PKHILDKIPPEIQPDDNAVKSICVDVLADIIDTIYRETNGRVKCFHFYTLNLEKAVAHIV
AKSDVLHHIMKEAEEEEEEEEAKTNVDQDGDIALDDGPGTTTLQEDNRKRRRNSSNVSTN
FTSNQLAVHKTRRSSIGIPSRKVAISISQGTGTLGRDATWDEFPNGRFGDSRSPAYGEID
GYGPSIKAGSKRALQLWGSPTNVEDLRNIFIKYLENSIDSLPWCDLGLSPESALIQEELI
QLNDRGFFTLASQPATNGASSTDKILGWGPAHGVVYQKSFVEMFVQKERWNTSLKHIVDH
YGREKLTYYVGGSDGSFGSNLEPGSSNVVTWGVFANSQVIQTTIISEESFKAWRDEAFSI
WLEWAKLFPRNSQSNSFLRQMHQDYYLVSVVHHDYNQSDELWEILLS
>A0A7J6JGT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum fructicola (strain Nara gc5)|TrEMBL
MDKITDKIAALPADANYFSLEFFPPKTVMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
SQKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKSE
YRTAEDSDVEDMDDFVWAIDLVKYIRKKYGDYFCIGVAAYPEGHADESHPLGQSFEHDLP
YLVDKVQAGADFIMTQLFFDIKAYDNFEKVLREHPSGAFKTIPLLPGLMPIQSYQMIKRT
TKLSHAKVPDALMARLDAAKGDDEKVKRVGVDILSELVEQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPEHADDDNESAIIDDAVVPTVQLNGLNPMSAVPRALSNSNRRASS
IGSDPHNRVIVSSASNPAYETTAASLSAEPVNTRANTLAISEGEGVLGREATWDDFPNGR
WGDARSPAYGEIDGYGVSLHMSVTQAVGLWGTPKTVQDINNLFIRHIKGQLSAIPWSEEE
LLPESNIIQQELLELNSRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKSFVEFFLPS
ADWAGLVARLNEVKDKSICFYAANAAGDFVSSDSSGGLVLEGTETSTNAVTWGVFPGKEI
ITPTIIEEVSFRAWAEEAFKIWGEWAKVYGKGSESEALLERIRSEYWLVNIIHHDFVERD
ALWKLLSGEKEI
>A0A833H5M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptonema illini|TrEMBL
MNKILLEVIPREVNTLLNEVSYVKNSYSQISGINIPDLLRFETRSWEAAVAVKSIFSNVI
PHIRAIDFDINNCDPIITFLRENQISSVVVIKGDPPADMSKKVFPTTSIKLIKKLKKEIP
SLKVYAAVDQYRAGIRDEFDYIEMKKDAGADGFLTQPFFDLRLIDIFTEKLHGTEVYIGI
SPVITEKSQSYWESRNRAYFPKDFKLTMDWNTSFAKDVIGYCKKNGLNTYLMPIRINIEE
YLASLFGRDTSVIRNT
>A0A656HHZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiothrix nivea (strain ATCC 35100 / DSM 5205 / JP2)|TrEMBL
MNDLHEHEHEHEHEHEHEHEHEHAQRDDLIFSFEFFPPKTEKGVENLRAVRTQLAELKPR
FFSVTYGAGGSTQTNTLNTVLEIQRDSDIEAAPHLSCVGSSAEQIREILETYRDNGIRHI
VALRGDLPSGTRDIGEFRYANELVEFIRKETGDHFNIEVAAYPEMHPQAPNLKVDIDNFV
RKVNAGANSAITQYFYNADAYWHFVDTCADKGVDIPIVPGIMPITNYTQLARFSDMCGAE
IPRWLRKQLETYGDDVESIAKCGEEFVTLLCENLLETGAPGLHFYTMNRVEPTMSIWRNL
GLSE
>A0A539DXC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSAQSVPHTATGTQRRLVAEARYELVPMKSVESQIEHVPAGSAMSVTCSPAKGLAATLEL
TARLLDRGFDAVPHLSARLTEDRAHAARLAAFCKQHGIREVFLVAGDAPEPVGAYDGVVA
LLRDFLDCDHGLTHIGVTAYPDGHALIDHAVVHEALHAKQELLAEAGLGGFATTQMCFDV
DQWKRWAQAERAAGLTLPLHLGVPGAIDRAKLLTMGARLGIGSSMRFVKKNPSTLLRLFS
PVGYDPAKLIAPLSRVAGELGIEGLHLFTFNNVEGTAAWQRKQLARLR
>M2QM94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceriporiopsis subvermispora (strain B)|TrEMBL
MKLSDKIAQHAGEHPFFTFEFFPPKTDLGFENLLSRVTRLAALHPLAVSVTWGAGGSTKE
RSLDLASFTQSNGMDTILHLTCTNMMQGTVDEALREAKARGVENILALRGDPPRGEEYWI
PTDSRFSHATDLVRYIRSSPEFSSEFCIGVAAYPDGHADHETGEVDELEYLKQKINAGAD
FIFTQLFYDVNNFIEWVKKVRQKGITVPIIPSIMPLQTYASFLRMTKLAGTRVPPSLMED
LMPIRHDDQLVKDYGVDLAIRMIRKIAAESDIPGVHLSTLNLEVSVIRILEELGWAGGPL
HPTNRLIADTTQESASRVITPHCATDSAATILAMSGPQTEGEAGKGELNNAVGWDDFPNG
RFGDFKSPAYGNTDQWGSTGLSRKQTLEQWGNPKTVDDLTQIFLLHLQSKIATTPFSPTP
LSPESLMIFPHLEKLTRRGWWTICSQPAVNGAPSTDEVLGWGPGDGYVYQKCFVEFFAER
EDVDKLEQKVAEAGNGWVHYFAGNVQGECRTNVSEDGRNAVTWGVFPGQEVVQTTIIEKE
SFITWKDEAFSIWAEWASFYPPDSPERQLLEGIRNRRWLVSIVHHDYIDPDALWTFLFSK
EEPLV
>A0A3N2FLX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. PhB127|TrEMBL
MTRARFEIIPSDGIGEKAERAFPDPAAVTLTVTSLPKHGTARTIDAAVELAGRGFRVVPH
LAARNVEGREALERALGRMRDAGIDEAFVVSGDARSAAGSYSTSLELIRDARELRPELAV
DIAGYPEGHPHLSDESIAKHLRERAPYLRGIVTQMCFDVDAVVRYADGLRADGIDAELWA
GVPGPVERARLLSLGARIGVGSSLGFLQRSSSVAGGLLRGRRFDPAAFVGRLEAAAGDRL
AGLHVYTFNELDGLRAF
>A0A1Y3M5H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter agilis|TrEMBL
MADLPVRIEVIPGEGLVERLQAHLPAPAVVTVTCLPHHGPRQAVDMAVDLARAGYTAVPH
LAARSVAGRAELAEYVAQCTKAGITDVFVIGGDAADAAGPYAWSGALMEDIADLSGGALR
MGIAVYPEGHPGTAQEELARTLRAKQELASWCVTQLCFSPDTLRAFPSVLRLDGITLPVW
AGIPGPVRMSRLLRLAGRIGVGQSLGFLKRSAGSANTGSVVRQLLSSASYDPAPLVDALD
GAGYAGLHLYSFNDLAELAASELAGQGRA
>A0A351M0H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSTRNKADRAVQKRLLEGMTYELIPLKNLADQSMFLPAGSTVSVTCSPAKTVDDTLDLCA
HYSSQGFTVIPHLAARMVEDEEHVERIARRINELGIRTVFCIGGDAEPRGPFTDTAGFLR
SFLDRRPEIDTVGVGSYPDGHATIPDQALVDGLVEKQEMIREAGLGGYMATQMCFDATTI
ADWLKGRRDAGVDLPCHLGVPGAIDRTRLLTISIRLGIGHSARYLKKNSASVIRLLSPGG
YNPSKLIDPLSGVAEELDIVGIHCFTFNAVDTTEDWRQKALQKLG
>A0A4Q6X4J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp. UYCP14C|TrEMBL
MNPIELSFEFFPPKTQEGIDKLRATRAELASLKPKFVSVTFGAGGSTQQGTLDTVIDMAK
DGLEAAPHLSCVGSSKDSLRAILNEYRAHGIRHIVALRGDLPSGMGALGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARQLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCQRLVDAKVPGLHFYTLNAATSTKAICERLAV
>A0A3D3QYC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIQNANGKTLFSFEILPPLKGQNIQSIFDAIDPLMEFNPAFIDVTYHREEYEYVE
REDGLLEKRVVKKRPGTVGICAAIQNKYGVDAVPHILCGGFSKEDTENLLIDIDFLGIHN
VVALRGDAVKTETYFKPEKNGHAFAKDLVEQIVKMNHGTYLDESLENSACTDFNIGVAGY
PEKHMEAASLEQDIYHLKKKVEAGADYIVTQMFFDNQKYYDFVEKCRTSGINVPIIPGLK
PITTKSQLSMIPHRFKVDLPNELVIAVAKAKDNKEVKEIGINWCIQQSKDLMKNGAPVLH
YYSMGKSEVVKRIASEVFKD
>A0A2E0IFY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ahrensia sp|TrEMBL
MRHSVKRIAGAPGTGKDIRVSFEFFPPKNPQMEATLTDTINRLSPLSPEFVSVTYGAGGS
TKDTSRATLQTVLATGNTPAAAHITCVGATRDEVDAVVRDFAALGIRRFVALRGDPSGGV
GSSYQPHPDGYQNAAHLVAGLKAFGDFDISVAAYPERHPESPDLATDLDMLKRKVDNGAT
RAITQFFFDNDAYERYVERVRRAGIYVPIVPGIVPIHNFSAVRNFASKCGTSIPAWLADR
FDGLDQDPHTHSLVAAAVAAEQVFDLVDRGVDDFHFYTMNRPDLVFAICRLIGIRETGEA
ARRELHAA
>R4XEG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Taphrina deformans (strain PYCC 5710 / ATCC 11124 / CBS 356.35 / IMI 108563 / JCM 9778 / NBRC 8474)|TrEMBL
MVSPVGSGGRRLDDKIAELPHDASYYSFEFFPPKTQAGLDNLQARISRMSRFQPLFVTVT
WGTGGSTAEKSLELATACEKDHGLTTCLHLTCTNMDKKILDNALATAKEAGIRNILALRG
DPPRGEEYWTPNEGEFVYAIDLVRYIRKEHKDWFCIGVAAYPEGHADVTHPEALDPADDI
PFLAQKVEAGANFILTQLFYDTDQFTKFHEMLLKYNSELFGKIPLIPAIMPIQSYQTLMR
MTSLSHASLPKDIHDRVEAVKGNDEEVKRIGVEISIAIIQDLKMKTNNHVRGSHLCTLNL
EKSVALTLMGSGLYVKPSRESSPTRTNGDVKNRAHVDHLSPDKKKDSKTKQVASNTSPDG
QDSEALQAVNISEGLGSKGREATWDEYPNGRFGDSRSPAYGELDGWGVSLGVPVRKALEM
WGRPESTNDITKVFVDHIAGKIMGTPWSTEPLSTETEVIRSELLSLNEKQLWTVGSQPAV
NCAPSDDSRFGWGPRGGYIFQKSFVEFFAKEDQWNAIKERIKDDSQISYYAGTRRGRFES
NMAATDANAVTWGIFPGKEIAQPTIIEEVSFKAWREEAFALWSEWERLYEPGSPAARLLR
QVTERFWLVSIVHHDYKDESALWKIFV
>A0A2E2J2D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIEKSHGKTQFSFEILPPLKGENIQSIFDAIDPLMEFNPPFIDVTYHREEYVYKE
LDNGLLQKQVVRKRPGTVGICAAIQNKYDVDAIPHILCGGFTQEDTENFLIDLGFLGIDN
VMALRGDAVKSETYFKPEKEGHHYASQLVSQIANLNHGVYLDEEVQNNTPTDFCIGVAGY
PEKHLEAPSMDSDIYFLKKKIAKGATYIVTQMFFDNSKFFQFVEKCRKEGIEVPIIPGLK
PLVTKKQLNLIPHRFNVDLPDDLIREVVKCKDNDQVREVGIEWCLQQSKELVKAGVPVLH
YYSMGKSVNIKKIASQVF
>A0A6I1TVH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETITDLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A160V9W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKITEGCFEATGHTSIICDFSPPRSGDSAVVTQAQIDADFISVAYNPGRAVRTNSAMLAA
AIQQSGKDAVFTLATRDMNKLAVQSLLLGAQLLGLQNVVVVQGDLFGEQDQARVATVNDY
HSTGLISAIVQMNQGQDFKEAELRAPSDFCIGGTVDLGRGIEEEAQLAVRKVQAGAEFLI
TQPIFNVDHVARYRESYAYNAGKAGTLPIYFGLQILEQDGVLFSSVPESVRADLEGGRSG
VDIALELYQEFQKARLNNVYLMPPIKRGGARNYEAAKEFLTLIK
>A0A3B0V2K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MDKKLFAERLRERSFLFDGAMGTLLHNRGVSMAQSFDGINLTQPAVVADIHRTYIAAGAD
IIETNSFGANRFKLAEYGLQEQVTAVNQAAVNIARRVIDSAFREVWLAGSVGPLGVRLTP
LGRVSLTEAAAAFREQIDALLTATSTSSIQAVPHSIDLLVLETMSDLQEMETAVSVAREL
ALDIPIVAQMTFTRDDRTLLGHTPDAVAQRLAALDVDAIGVNCSGGPAQVLRLLLMIGQL
APDKLLAASPNAGWPEQTQRGRVLYPATPDYFGQYTHALLEAGAVLVGGCCGTDEAHIAA
MRHALDHPAPSSIPLPQIQIVTQAKRQTAVLDPPTQLAQNLANGRFIVTVEMSPPKGIAT
QRLIEGAHMLKEAGANLLNLADSPLARMRMSGWAAAHLVQKSVGLETVLHFPTRGRNLLR
IQGDLLAAYAMGIRNLFVTMGDPTRIGDYPEAMDSYDIVPTGLIHLIKQQFNSGVDKAGQ
SIDQPTNFMVGCALNLTSTDPERDLKLLRRKIGNGADFAVTQPVFDPAAAKRFVDLYEST
YEEKMLPLIVGVKPLFNGRNAQFLHNEVPGMSIPEPLRQRMAQTTEPQQEGVAIAQEILL
AIRPFAQGVYLMPAFGRYDLVANVMDALAEVTIFD
>A0A849H413|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Silicimonas sp|TrEMBL
FEAETFLRFRDRCDAAGIDIPVLPGILPIQSWNGVRRFAERCGARIPDTLALAFEAAERD
ERSDLLALTQCTTLCTRLLDEGAGHLHFYTLNKPDLTREVIHALGLAPAAVLENVA
>A0A3Q1EHY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acanthochromis polyacanthus|TrEMBL
MVNQVQQGDGNCQSSKSDSSGSNSGGESSKESSRCSTPVLDADRSDRLRDKMRRRMESGD
HWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQTKGKITDYLTKAKRLGLKNIMALRGDPLGEDWEEEEEGFNYAVD
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGADFVITQLFFRAETFL
KFLEDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEDITKVIEPIKDNDAAIRNY
GIQQAVKMCRVLLESGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELMNEESVNEIFTCYITAQPNRGGHKVLCLPWNDEPLATETNLLKDELEKVNKR
GVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPVSFMSWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPEPLNDGAVSE
>A0A6A1TSG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neorhizobium galegae|TrEMBL
MTADSETFSVSFEFFPPKSDEMEGQLWDTVDELALWDPRFVSVTYGAGGSTKAPTINTVR
RLVGETSLVTAAHLTCVDATHEETHSVVSEYRAAGIRHIVALRGDPASGVGTEYRPHPQG
YANAADLVRGLTELGGFDISVSAYPEKHPESADLGADIEMLKRKADAGAARALTQFFFDN
DVFERYLEKVRAAGISIPIVPGIMPIQNLTQLKRFAGRCGSSVPSFLDARFEGLDDKPED
RAKVAADIAAEQIEDLIRRGLGDFHIYTMNRAPLVSAVLQRLGRRQIRTPRIAAA
>A0A081RD22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium chlorophenolicum|TrEMBL
MTLGFPSVEAAQAWQAPLYADLAGDVNVSFEFFPPKSEKMEEQLWSAIQTLTPLAPKFVS
VTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKAEIDEVADAYWEAGVRHIVAL
RGDPPEMGAKFEPHPEGYKGAAELVAGLVKRHPFEISVAAYPETHPDAQSAQSDIDNLKR
KLDAGATRAITQFFFEPETFFRFRDTVAAAGIDADIIPGIMPVSNFAAVQRMSAMCNTDV
PGWMGKLFEGLDDHAAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVATNAV
>A0A7J4ZMA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzomonas japonica|TrEMBL
MKIIDIIIPDKPFLSLEFFPPKERSEWPAFFHTVDRLKEVNPLFCSVTYGAGGSTHGDSL
EIVGRLKQEHGLETMAHLTCVGAHEDDVRTFLDQLTRAGGDNVLALRGDLPQDSTPKSSP
HRPLAHASDLVALIRDSHPHVGLGVAAYPEVHPEAASTAADLAYLKLKLDHGADFAITQL
FFDNRIYFDFVRNARDHGITKPIIPGILPVVSLKVIKRIVSLCGTVMPPDFMAQLEEADR
RGGAAEVQKLGVAHARRQTEELLAGGAPGVHLYTLNRADAVLEVTNGLCPPQGATP
>A0A6G0R1Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora fragariae|TrEMBL
MGKISDSIRSAYAARADDASTHPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFTDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGAERWAPVEGGLSNAVDLIKLIREEHGDYFCVACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIQWIADCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPESVLTALDAIKNDDAAVRRYGTQLAVETCQRLLAAGVNSLHFYTMNLATT
VTQVLEGLKMLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRTDLWGTPQTEQDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAAIRENLQWINSNGFLTINSQPRVNGAPSSDPSVGWGGDDGVVFQKAYVEFFVA
PEKMAHLVKVMRRDYPQLSFHALNRKGDEHRNTPLHSVTAVTWGVFPGTEIVQPTVVDSD
SFAAWKDEAFELWQTQWASAYPADSRSREVVQHIYDTYFLVNIVDNDYANDESDIFSIFT
RIITEAMDKEQLRARVLELETRREKMFDTLASFQSLQEELNGELRSVHSELAGVRSENLQ
LKEKVRQVQAQLALASL
>A0A2U1AI33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Victivallis vadensis|TrEMBL
MNLLQQKLAESLTIFDGAIGTEIYRRNFFVNASFEQLNLTAPDVILDIHHQYLKAGAEVL
TTNTYNANSRRLAKFGLSEQTEAINRAGVKLAREAAAGKALVAASVGPVGEPDSDQDRRT
RAELLAEQIRALSDADFIIFESLRRAADLKAVLEAVAEFPELVYVPSFAIEPHPHINDSA
TIAEFMEQLNASRPCPAPTAIGLNCGGGPESTLGVLEELTALTQLPVIVQPNAGQPKGVD
GRMIYMTSAEYFSTYAKRYAMLGAAAIGGCCGITPDHIEELARTIKPLMQAEKRALPALE
VKECDLKPEVPLAERSRIGCKLADGAFIKLVEITPPRGFDLTGTIAGAAKCKAAGIDAVN
LPDGPRASARISPLVTALEIQRNAGIETILHCCCRDKSLIGLQADLLGCAGVGINNILFI
TGDPPKLGDYPFSSGVFDVDSVGLVKIQKRMNQGVDLGGKPLNAVTKMVIGVGADPNAID
LEREYRRTCEKVEAGAEFIITQPVFAPEALFVFLDRVAHLNVPVIAGIWPLTSLRNAEFM
RTEVPGVVVPDAVMERMAADESKEAQREAGIAIARESVAAIRSRVRGIQVSAPFGNVDTA
LRVLA
>A0A1H4EU58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lonsdalea quercina|TrEMBL
MSFFHANHQEALNQSLAELQGHINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKAIKERIGVDAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPPEGGKPELYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRVPNWMTAMFD
GLDHDPETRKMVGASIAMDMVKILRREGVKDFHFYTLNRAELSYAICHTLGVRPAIAA
>A0A1M6VQ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWH4|TrEMBL
MKIVDILKQDKMSLSFEVFPPKKETSFDNVKAATESIAALGPAFMSVTYGAGGGVSQYTL
QIAKNLKEKFGIPMLAHLTCVSSSKETIRQRIEDMRAAGIKNVMALRGDLTPELIANGRD
NCDYHYAVELIRELKDADADFCIGAACYPEKHPESANQAEDIKHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPDAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFA
>A0A3R9QE31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIVALQNMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLTIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDIPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1X1JM46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3B0RIE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
FKRLHVAGHPEGNKDIDPKGGTANVDAALRWKQAFSETSDAEMALATQFAFEADPIIKWA
DSLAAAGITLPIHIGIAGPAKLQTLIKFAIACGVGPSLKVLQKRAMDVTKLLLPYEPTEV
IARLAAHKAANPDFNITHVHFFPLGGIKTNATWAKDHGGPAAQPVNTTPKDPT
>A0A2N0XI37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. PMSZPI|TrEMBL
MKITEHIKKANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIEN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINNLGRGKYLHNEDSVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKRHLKLLPQVFKIDLPEELINEVESAKNNEAVKQIGIEWAITQCKELLGFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A3D3AH86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetia bacterium|TrEMBL
MNIQEVLSQKFSFSMEVFPPKKEGDVKELFQVIKDLKILNPDFISVTYGAGGSTQSMTRE
IASEIKNKIGIESMAHLTCVGNTKEEISAIINDLRESNIKNILALRGDPPAGMKEFQVKQ
GGFAYASELVDFIRQNQNHFSIGVAGYPEKHPEAGSLEKDIENLKKKIDAGADFIVTQLF
FENEAFNRFMDKIEKAGIRIPVLPGIFLVSGYNQLKRITELSNAEIPKKFHDNLLKYQDK
PEDLKKIGIEHALMQSEDLIKSKRIGGLHFYIMNRKDMILPIYEELKGFF
>E6ZP86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporisorium reilianum (strain SRZ2)|TrEMBL
MVNGTDSPLPPKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADL
GPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGC
RNILALRGDPPAGQSEWEPHAAGFTSAKQLVEYIRENYGDYFAIAVAGFPEGHPEAVDGP
EKELERLKEKIDAGADFIFTQMFYDFDIFAKWVKDVRAAGITCPIVPGVMPIQTYGGFQR
ATARFGTLVPQYFHDALDPVKDDDQKVRDVGTRLVGEMCKKIVGTGLGISGLHIYTMNLE
KGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRREEKIRPIFWANRAKSYVNRTETWDEFP
NGRWGDARSPAYGDVDAYGVKLRYSNEEAKEMWGAPTSLEDVKALFENFCAGHVKALPWS
ETPVARETSVISDKLTKMNQLGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEFF
VSPEDLDALIARIEADPQITYHAVNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVES
ISFLAWKDEAYEIGRNWAKVYEPSSPSRKFLEDMFNKYFLVNVVHNDFKAADSIFEPFLN
ASKATTAVNGSLSGLGATVSDAAGRVANSISSLTNGTSNGHASAPAPAA
>A0A3R9R3G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLNKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRSQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3M2VY02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. ribicola|TrEMBL
MEVPSPMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLN
TVLQLENEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIKRIVALRGDLPSGMGMASGEL
RHANDLVAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFN
ADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQ
SIQAFGEDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A373H1M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. AM23-13AC|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A3B0SFB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MTKRNKPMALSELEEAKRALDVPLFAGLSGDADVSFEFFPPKSEKMEKTLWDSVVTLEPL
APRFVSVTYGAGGSTRERTHATVARIARETNIPAAAHLTCVDASKSEIREVAQSYWDAGI
RHIVALRGDPSVEGQAFQPHPEGYASAAELVAGLKDIAPFEISVAAYPETHPEADCPQSD
LDNLKRKLDAGATRAITQFFFTAEAFFRFRDAAVSAGIDAELVPGILPVSNVAQTRKFAG
MCGAEIPGWMNDLFEGLDDHPSARQLIAATVAAELCRKLYAGGVRQFHFYTLNRAELSYA
ICHLLGKRPVGAAREKAA
>W9PZ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. pisi HDV247|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDDVKGDDERVKMVGVDIVSELIDKIKTIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>J5KMR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR86 cluster bacterium SAR86B|TrEMBL
SYKNGINIEITPGIMPIYNIKNILNMSQRCGIKIPDNIKNKFGDDENENFKKSLDVCHEQ
LDYLTQLGYKSFHFYTLNRYKFIKQLFTERTAV
>A0A160TWE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MILDEKIAHGGIIVLDGATGTEIERLGGKMDSAAWCAVANMSYPEKVQQVHEAYMRTGVD
VITTNTFATCRHVLAGAGLDNDTVAINQQAVALARKARDAVAPSRPVAIAGSMSNTVAWQ
PGFISPDPRFIPTERQEIANYREMANTLADSGVDFLILEMMLDIEHASRALEAAVGTGLP
VWVGISCSLENDGAVVGWDLATQGRITADHVPPLPLPLDEIVDALQKIGGDVFGIMHSTV
GATTPGLQVLCERWTGPVMAYPETTRGVQPPVDQTDRLPTPSFLDVGNVSPEIFAEACRG
WVDQGVQIIGGCCGATIEHMQAMIARLPAQVGNRLPVG
>I3Z9W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Belliella baltica (strain DSM 15883 / CIP 108006 / LMG 21964 / BA134)|TrEMBL
MKITDYIAEAEKTLFSFEILPPLKGQSLKDLCEGIEPLMEFNPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFQVAAVPHLLCGGFTKEETENALIDLNFIGVQNV
LALRGDAPKSENKFVPEPDGHTYTKDLVAQIVGMNHGRYLHEETETGFQTDFCVGVAGYP
EKHFEAPSLKFDLKHLKEKVDAGAEYIVTQMFFDNEKYFDFVKKVRDIGITVPIIPGLKP
ITTLGQISMLPRTFFLDLPDALMDELEKCKSNADVKQVGIEWAIQQSKELIAAGTPCLHY
YTMSKAGATYKIAKEVF
>A0A1G7JV05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terriglobus roseus|TrEMBL
MSDVSLPSIDRIFGSRPILCDGAMGTMLYARGIFINRCFDELNLSEPKMVRDIHEEYLLA
GAELLETNTFGANAVRLRRFGLENKVAEINAAAVKLARDAANAVREKHAHHAYIAGALGP
LGLPEPERDADVMIAAYREQVQALADAGVDLFVVETMTSMAEAKAAIDAIRQVSTNLPII
AMVTVTDAGNVSDGTSPEEAAKLLAEWGANAIGCNCSDGPQLVLDTIERMRRVTSLPIAA
MPNAGVPSCVDGRSIYLSSPEYLASFARKAMRLGATIIGGCCGTTPQHIRAMRSSVKAIQ
SQAEGVAQVGDKPAAAVIEPAPLAERSQLGRRIATGEFVTMVEIVPPKGFDPSRELEGAR
MLKKLGVHAINVPDSPRASTRMSASSLCLQIEQKIGIETVIHFTCRDRNLLGIQSDLLGA
ASLGMKNILCLTGDPPKMGNYPDATGVFDVDAVGLTRVLRDMNHGLDIGGQSIGASTGFV
LACAANPGVPDLDMEVRRFAAKVEAGAEFAITQPVFDLKLLETFLKRIEGFRIPVVAGIW
PLTSVKNAEFMKNDLKVRMPDQILHRMAAHAGTPEQSRAEGIRIAQEMLAEAQPMVQGVQ
VSAPFARYAAAAEVLEALLVPVTAE
>A0A3M9ZLQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon S14|TrEMBL
MFSRSWSISGANTFSNASGVTARPPCHGLINATGHGPHRRGGARDDLDMAARAAARSVLG
IVYEANPPRDEGDAGGLLEAMSRRLGRVIGLADAVLVTDGVLGTRRVGVLDACAAIAASH
PRAEVMISLRTRDRTYERLAGDIAEAARVGVSAVLLVRGDPPQYAGARDTNLYPGAALSR
LRAESRTCGVRMVLSLPAEPDPAGTRKKLAARPDAFVTQVIASEAQAAGIVEEMAAHGIG
VTPCVMVPSEKNAPSARALGLDWSAYEGDCGAFVRRIHSLAGGVLVTSPRDLAAAEAAIA
SAR
>A0A5P8RY71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pestis subsp. pestis bv. Medievalis|TrEMBL
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIAIDYWNSGIRHIVALRGD
LPPNSGKPEMYACDLVGLLKDVGDFDISVAAYPEIHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFD
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A7X1F7P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium aerophilum|TrEMBL
MTLPATAPLFADLPGDISVSFEFFPPKSEKMEEQLWDAITQLAPLQPSFVSVTYGAGGST
RERTHATVARIVRETSLVPAAHLTCVSASKAEIAEVADQYWEAGVRHLVALRGDPPPADG
GTFVPHPQGYTCAADLVAGLMARHDFDISVAAYPEVHPEAASAQSDLDNLKRKLDAGANR
AITQFFFSTDAYFRFLDKALAAGISAPILPGIMPVTSFAAIRRMSANTEIPAWMEAMFEG
LDDRPGPRALVSAVAAADLCRRLYAGGVRDFHFYTLNKAEQAYAICHLLGLRPKG
>A0A8C6NG90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melopsittacus undulatus|TrEMBL
MVNETQHSCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTRDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAIDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNY
HIVNVKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSQTQQ
>A0A2P2FT80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis lurida NRRL 2430|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPEGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSADLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTPRTLHTSIKLSGAPAPRRLLDRLEPLA
GDPKAFRAAGIDAVTELGERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A1I5BXU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio sp. JW11|TrEMBL
MFKDMFANDSSLSFEVFPPKKDDEFENCYKVLDSLSELKPDFISVTYGAGGSRSKKTVEI
ASYIQNELHTDAMAHMTCVGSSSEDILAVTRDLEAVGVNHVLALRGDKPRDMSDEQFNKR
VFPHATDLIRFLNENTKLDISASCYPEKHPEAMSMDSDLAFMKMKQDMGAKMFISQLFFD
NADFYRFTERADKAGITIPIVAGIMPITSAKQIGSTVTLAGSSVPKKLADICARYGESPD
DMRKAGIEYAIDQIRDLRKCGVGHIHIYCMNKPKMTAEICTSI
>A0A0J9UZE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936)|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A1G7M3V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas seleniipraecipitans|TrEMBL
MSQKRPTVSFEFFPTKTDAGHEKLLNTARELAGYNPDFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDSKAELIELLNLYKSNGITRIVALRGDLPSGMGMSSGELRHAND
LVELIRRETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADCYF
YFVERIRKLGVDIPVIPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDTQSIQRF
GEEMITGLCERLVEGGAPGLHFYTLNQAAPSLAVWKNLQG
>A0A553E1S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium restrictum|TrEMBL
MKVTQHIENANGKPLFSFEIVPPQKGTNIKDLYENIDPLMEFNPPFIDVTTSREEYVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGVDAIPHVLCGGFTKEETEYLLVDCQYLGIDNL
VALRGDPMKGEKYFEPTKGGNHYAVDLVKQIKAMNAGQFLHEVLPMQNAPDFCVGVAGYP
EKHIEAPSLDADLKRLKEKVDAGADYVVTQMFFDNQRYFKFVEAARAIGITVPIIPGIKP
VAVKRHLQLLPQVFWLDMPESLISAIENAKDNAAVRQVGIEFAVQQSKELIEFGVPCVHY
YSMGKSDNIHQIASLVF
>A0A365ZUU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella sp. PE36|TrEMBL
MKSAHCPTFSVEFFPPRDEPDEAVLWRAIRELEPLDPAYMSITYGAGGSSRDGTIRNIAR
VATDTTLVPMAHLTAVNHSVAELRNVIGHFAAVGVHNILALRGDPPGDPMGEWVPHPQGL
HYAEELVRLVRELGDFCVGVSAFPYGHPRSADLDTDTHYLVRKLRAGADFAIAQLFFEAE
DFLRLRDRVAAAGCEALMLPGIMPLTTPRTLRKTIELSGATPPAWLVDRLAPLEDDPKAF
RAEGLDVVTELCSRLLAEGVPELHFYTFNRSKATRELVERLGLRSPAPPLAVAARP
>A0A448UCX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria animaloris|TrEMBL
MTSNQKKLSFEFFPTRTPEGRAKQVVTRKQLSQFNPEFFSCTSGAGGSTKQGTMQAIQDI
LSEGVPAAPHLPCVGMHHEEIVDLLNEYKKIGVRHIVALRGDIPSGAGVGGEGLRYANEL
VSLIKNEFGDDFHIEVAAYPEYHPQARSAEDDINNFVRKVKAGADSAITQYFYNADAYFR
FVDDVTGRGVDIPIVPGIMPIASFSKLARFSDTCGAEIPRWLRLKLQSYADDTAAIKALA
LDVVTEMCERLLREGVPSLHFYTLNQAGLVSTICQRLGY
>A0A554W991|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidimonas alkaliphilus|TrEMBL
MALPLSFEFFPPKTPEGAAKLRAARQRLYAARPQFCSVTYGAGGSTQEGTLATVAEILAE
GMDAAAHFSCIGATRERVRAQLAELQRMGVKRLVALRGDLPSGYGLGGEFTYARDLVAFI
RAEFGAAFHIEVAAYPEMHPQARSLQADLQAFADKVRAGADGAITQYFFNTDAYFRFVDE
AYALGVDVPIVPGIMPITNASQLVRFSDACGAEIPRWIRLRLQGYGDDVASIRAFGLDVV
TDLCDQLRSAGVPGLHFYTMNQAEPTLAILQRLGMIEAG
>A0A735KYR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. houtenae serovar 16:z4,z32:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2D6IWK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MTDTDRLQVSFEFFPPNTPAMETTLWNSIQRLAPLRPRFVSVTYGADGSTRDRTHRIVSR
IIAETGLRAAPHLTCVGSTKEEVQAVARRYWDEGIRDIVALRGDPPADAEKYEPYPGGYE
YGVDLVAGLSEVAEFEISVAAYPEVHPEAPSAAFDLDCLKRKLDAGATRAITQFFFDVDN
FLRFRDQCISSGISASIVPGILPINKFPQLLRFANMCGASVPEWLHERFEGLDDDDETRQ
MISANIAIDAAERMRAEGINEFHFYTLNRAEQTYAICHALGLRPRENQAGAGGVTKHG
>A0A1E4TKA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tortispora caseinolytica NRRL Y-17796|TrEMBL
MLISDKIKESKSSKGADFSLEFFPPRTDIGAHNIQDRILRLSSLNPLFVSVTWGAGGSTS
EKSLQLAEYCQSLGLTTLLHLTCTNMDRSVLDHALRRAKDLGIRNILALRGDAPRGQEYA
VESSDEFKQASDLVKYIRSRHGKYFCIGVAAYPEGHRDISSLSPQSVLKDLPYLIEKVES
GADFIMLQMCFSADTIINFINGLRQAHPCFKDIPIIPGLLPINTFQSFARATQLAHCAVP
PNIYSRLSEVANDDSKVKEVGVEILSDLCNELYTKSYAEIRLFHFYTLNLEKSVALVLDR
SNIFKLPPHMSSVDVTPPFQENLGNSSRRRRRSSLSTHNKVLVEEARRTKSAKFTSDIVV
ESIDPNGHEQLALAISTGEGELGRQATWDDFPNGRFGDPRSPAFTLSGYGADPYSTGLAI
SRIPTSRALDLWGAPETVDDISKLICNHLTSGTPNSFLPWSDSLQDLSDETTTIAQELLL
LNESGYWTISSQPALNGVRSSDPIYGWGPDNGYVYQKAFVEFFISTEKWHRLKERLDSMP
EGEVSYYACGSNPSTYVSTGNETNAVTWGIFPHREVLQPTVIEPLSFQTWSEEVFRAWKT
WQSLFASHTKSFKLIQDIYDTYYLVALVHHDYIGNPSRLWEYLLQ
>A0A416Q6T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF21-3|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A2A3B6E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3866|TrEMBL
MSIRHQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVF
LGAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRNFMQKARDLGHTEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>A0A3G2GQE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 140616W15|TrEMBL
MKVTKHIEKAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
VMALRGDAMKDEQYFIPKAGGNDYAVDLVKQISLLNQGKYLHEVMDVDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFNFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHEVDKCKNNAEIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A316YXZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acaromyces ingoldii|TrEMBL
MHISARIEKAVAANRPFYSLEYFPPKTSQGLANLYVRIARMNLDLRPEWVQITWGAGGTT
QRTSLELAARVENGILDPDADFVAAFQRKQSDERLATNACLHLTCTNVERASLDETLDRA
LELGITNVLALRGDPPRGQEYWVAADDRFQHATDLVRYIRERHGDKFCIGVAGYPEMHPD
AASSSSSSSSAEIDYLLEKQRAGANFIVTQLFYDVDAFVHWYAACRARGITLPILPGIMP
IQNYQSFRRMTTLCKTKVPQAVWDALEPIRHDDAAVKEFGVRQATNIIRRLCDETDIRGF
HICTLNLEKSVRGLLESLGWVSPKTAVQKGPGGLLPDQQPWDEFPNGRYGDSRSPAYGEL
DGYGVSLKVAPQEALRLWGFPLAEADVSTIFCDYLCGRRTSIPWCDCPIMDETASIRSEL
LSLNSAQRTWWTVGSQPAVDGVDSSDPTYGFGPKAGHVFQKAFVEFFATGQHLAALQQRI
AASAGREEGWITFLAGNRRGDFVTNMREGDVNAVTWAVFPGQEIVQSTIIEEESFKAWRD
EAFAIWAEWELLFAKGSPTRELLRRIGDERWLVTVVHHDFKREKALWTFLDSVVASSS
>A0A1W1YN10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocicer vacuolatum DSM 3385|TrEMBL
MKSGSKLERTLEAGHFAFTGEVGPPRGANVEALREKIKPLKGMVDMANVTDNQTAMVRMS
SWAASMICLEEGVEPNFQMVCRDRNRLAMQADILGAYAHGLRNMLCLSGDHQTFGDHPQA
KGVFDIDSMQLISMVKKMRDEGKFLGGADIDEPPKMFIGAAANPFAEPFEWRVHRLAKKI
AAGADYVQTQCIYNMPKMREWVRQANEMGLTDKVHILAGVTPMKSIGMARYMQKKVPGMD
VPEELIKRLQGVDKKNVADEGIKIACEQIEEFKEMKGVAGVHLMAIEWEHKVPEIAERAG
VLPRPEV
>A0A0F7FQM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces xiamenensis|TrEMBL
MNDRAHTVRDLLAAGKRSYSFEFTPPRTEQGERTMWNAIRRVEAVGPTFVSVTYGAGGSS
RERTVRATERIATETTLTPVAHLTAVNHSVAELRNIIGQYAGAGIRNMLALRGDPPGDPM
GQWNRHPEGVTYAAELVSLIKESGDFCVGVAAFPEMHPRSTDWETDIRHFINKCRAGADF
ALTQMFFDPEDYLRLRDRVAAAGCDVPIIPEIMPIANLRQIERFKELSNSSFPEELENRL
RAVKDDPMAVRSVGIEFATELCARLMDEDIPGLHFVTLNTTLHSTATLDVYKNLGLHRAG
LEQR
>A0A1W2E9I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocicer vacuolatum DSM 3385|TrEMBL
MKSGSNLEKILKAGHFAFTGEVGPPRGANVQALREKVAHLKGKVDMANITDNQTAMVRMS
SWAAAMICMQEGVEPNFQMVCRDRNRLAMQADILGAFAHGIRNILCLSGDHQQFGDHPQS
KGVFDIDSMQLIGMVKKMRDEGKFLGGADIDIPPRMFIGAAANPFAEPFEWRVHRLAKKV
AAGADFIQTQCVFNMEKIREWMRRANDMGLTEKVAILPGITPMKSIGMAKYMKNKVPGMD
VPENIIKRLQGVDPKMVADEGIKIACEQIQEFKEMKGVAGVHLMAIEWEHKVPEIAERAG
VLPRPEV
>A0A0N1AT82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|beta proteobacterium AAP51|TrEMBL
MSGSVPISFEFFPPNTPVGSDKLKTVVAELAAVQPEFFSVTYGAGGSTREKTLATVKDIA
AMGHEAAPHLSCVGSTQASIREILETYRAQGIRRLVALRGDLPSGTAVAGEFRYAADLIE
FIRQEQGADWHIEAAAYPEYHPQQRYAKKDLEHFAAKMKAGADSAITQFFFNPDAYFHFV
DEVRKLGVTAPIVPGIMPIHNYAKIAQFAARDGIEIPRWVALKMEGFMDDAASVRAFGIE
VVARLCRRLIEGGAPGIHFYTLNQSALSLEVCRQLR
>A0A1V5XDG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin193|TrEMBL
MRYHIENKIYHVEILPPKQSTEKLEADLELFAEKYNRVMESGYCACITDNAMGLLAFQGH
EIINELNLKVNPEQVMIHLNTFHTKSNLCEILDTCMAKGIKYLLIISGDGSDRLPKLQPA
DVEAEDVQSVTSVELLRYIKRHYPDTFTLGVAFNPYEPPEHEFEKLKRKIDAGAEFIVTQ
PIIEKNAIVDEMIQKYPDIPVIVEAWMSKKLYLLSDAVGYPIPEDTEFDPIKTLMQIHRD
YPNCGVYLSLLGFKTQYHLIGETWRNI
>A0A2V3PQ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dysgonomonas alginatilytica|TrEMBL
MKVTDLIQNNGKTAFSFEILPPLKGNSIQKAYNIIDKLIEFDPKYINITTHHSENIYKEL
PDGTVTKVNVRKRPGTVAIAASIQNKYNITAVPHMICKGFSKEETEYALIDLNFLGIHNL
LLLRGDAHKLESDQLAGNMNQYATDLQVQVNHFNEGITADGGSFERFETPFSYGMACYPE
KHEEAPNLESDIYYLKMKQAQGAEYFVTQMFFDNSKYFSFVERCRAEGITIPIIPGVKPI
YKINHLTLLPKTFRSDIPEELAAELRKCHSDAEAKDVGVEWGIKQCKELIQYGVPSIHFY
ALMATESVRRIAKEVY
>A0A856N6C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S1A1-8|TrEMBL
MALGSASTRTDRARTVRDMLGTGKATYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDVDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCTTPVIPEVMPVTSVKMLERLPKLSNASF
PDVLKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A417PZR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium OM08-11AC|TrEMBL
MGNTKHTKEQIRERIQQKKLLFDGAFGTYYGGKYDTKQLPELANLEAPERVREIHTEYLE
AGAQILRTNTFAANSFCMDMSKEQIEETLRSGVRLAREAVAAWRARTGETKEVYIAGDIG
QIPGDALAQKDTLCREYEEICRIFLEEGVDFFVFETFSEMEEILPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGAIKEIDAVGFNCGVGPSHMYRILQTLYKPADKFLTALP
NAGYPQMVTGRMIFTGDNREYFVDRMQQMIALGVDMAGGCCGTTPEYISDLAGKLDFTQY
PQTQEKAEPEKKQAGTEDHSFYHNKEAEGGKKLIAVELAPPAGIDDEKLMDAAHLLQRSG
VDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGIH
NFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFAQAPVSYGGAINQGRRNLE
VEIGRVKKKMAAGATFFLTQPISTKESADRVRRIKEETGARILCGIMPFVSLKNATFMKN
EMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVIAMTEDFADGYYFSFPFNRVTMLEK
ILD
>A0A857ESN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mannheimia ovis|TrEMBL
MNYATQIDALNQHIADIGRKINVSFEFFPPKNEKMETMLWDSIDRLSPLKPKFVSVTYGA
NSGERDRTHSIVKSIQEKTGIISAPHLTGIDATPEELKVIAKDYWDSGIRRIVALRGDIP
KGYDKALFYASDLVALLKSVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVSIGIDCEIVPGILPVTNFKQLQKMAAVTNVKIPTWMGKMYEGL
DDDQTTRNLVAASIAMDMVKVLSREGVNDFHFYTLNRSELTYAMCHTLGVRPDLTTA
>A0A2A5JYA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus larvae subsp. larvae (strain NRRL B-3650 / LMG 16245)|TrEMBL
MLYAILSFYLQPFCYWIGIKLGGEKEMRPDLRLALQHQLLTGDGAMGTYLYQLGFPVGIS
YEELNLLQPQVIADIHRRYYEAGAKIIETNTFSANKEKLSKFGLEQEVKRINRAGADLAR
QTVGDDAYVMGAVGSIRGSKRKNVLEADVRIAFHEQVEALLEASVDGLLLETFYDLDELL
IALRLIRNLSDLPVICQFTTEGNHTTHDGIPLQEAFERLKDEGADVVGFNCVSGPNGIMQ
SIGRIHPLEQVPFSVYPNAGIPDYVDGRIVFGATPEYFAETALRFADLGARIIGGCCGTT
PEHIAAISKALRGYVPSAEQAFRLRGTETGRDEEHPVISTGTAETGDSSYMDGVQNLVDL
VKQRPTVIVELDPPRTLDINKFMVGAKALKDARVDAITMADNSLAVTRMSNLALGALVQQ
RLNVRPLVHIACRDRNSIGTQSHLMGMDALGIDHVLAVTGDPARFGDLPGSSSVYDLTSF
EIIRMIKQLNKGLAFSGKPLKKKARFVIGAAFNPNVKYLEKAVQRLEKKIAAGADYIMTQ
PVYDHALIERIHESTKHMDVPIFLGIMPLASGRNAEYLHNEVPGIQLPDETRGRMAGLEG
EAGRAAGTEMAKELIDTALQYFNGIYLMTPFLFYDMSVALTEYIWGKTSSRHPLLSRV
>A0A0P8C5E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedens sp. BLZ1|TrEMBL
MSFISKLRSGKFIITAEISPPKGTDTSRMLGDAALLKGIADAVNVTDNQRAAMRMSPIAA
CSILQEKGLETIMHITCRDRNRLALQSELIGAFALGIRNVLVMSGDHPSKGDHEGAKPVY
DLDSVQLLGMIQELNRGVDLSGNKLDGKTDFCMGAVTNTELNEAGLLKLKKKIKIASFLQ
TQAVFDVKRFSEFIEKKSEIELKQSKQIKIIAGIIPLRSERSALFLNKVPGIRVPDDMIK
QIKDAKYPEVEGMRITSDIIKELRTLCDGVHIMPVGNHEHTKKLLEMAGLI
>A0A417FHL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM32-17LB|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A317T5K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecochloris marina|TrEMBL
MLVKEILQSATKPVFSFEFFPPKKTADWDKLFHTISELIPFNPSYVSVTYGAGGSTRNRT
HDLVTKIQRETGLSVVSHLTCICSGKEEIRQILDEYSKHGIKNVLALRGDLPPGSASYEE
ATKDFPHAVDLVRFIAENFPDIGIGVAGFPEGHPQTPNRLQEIEYLKVKVDQGADYIVTQ
LFFDNRDFFDFVGRCTLAGINVPIIPGIMPVTTKKGLIRMSELALGARIPAPLLKRVLEA
SDDDEVVKIGIEWATMQVNDLIGNHIKGVHFYTLNNAEATRRIFQNIAESTKT
>A0A0D8DCJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassomonas viridans|TrEMBL
MGYSHARQVESLNRSLSEISQDIQVSFEFFPPNSPEMENTLWNSIERLAPLKPSFVSVTY
GAGSGTRDRTHDVIKRIQKDTALIAAPHLTCIDAGKEELVQIAKDYWESGVRHIVALRGD
LPDSSEKPSMYASDLVGLLKSVADFDISVAAYPEGHPEAPNPQFDLLNLKRKVESGANRA
ISQFFFDIESYLRFRDRCVTVGIDVEIIPGILPVTNYKTLERFAGLTNVHVPSWMPKMYE
GLEDDETTRRLVGANIAMEQVKVLNKEGVKNFHFYTLNRAELTYAICHTLGIRP
>A0A434F3L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2C.T.Ca.TU.009.01.2.1|TrEMBL
IQGDVLGGAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGR
KLTTPPQVFLGCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDL
GHTEKLFLLCGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIIN
EVKEIPGVAGIHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDE
LTETQVDMVKTAH
>A0A2S6H869|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacter tundripaludum|TrEMBL
MQSQKQHPQLFSFEFYPPKTEEGAASLQIVQSKLAKLNPDFFSVTFGAGGSTRDKTFVTV
IEIQAKGVAAAPHLSCVASTKDNIRAILKDYQDHGITKIVALRGDLPSGMMSAGEFRYAN
ELVEFIRQETGDHFQIHVAAYPEVHPQAANGVEDFKNFKRKVAAGANAAITQYFYNAEAY
FYFVDACEKNGITIPIVPGIMPITQYTQLFRFSEMCGADIPRWLRKRLESFGDDKESVQA
FGLDVVSNLCQRLLDGGAPGLHFYTMNQAAPTLAILDNLHIKPQK
>A0A1W9RV77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium 4484_70.2|TrEMBL
MNFQQKLENNNFVYTVEVEPPKGVMVEDTLKELVSLRDIIDAFNVTDMQASVMRASSWAL
AAKLKEKRLEPILQLAARDRNIIALQGDLLASFILGIKNLLLLTGDTPKKGDHPSAKEVF
EVDSIGLIKIAHRLNQGFDYMGNKLKGKPQFFIGAALNPLAQNIDKELKKMEEKIKAGAS
FFQTQPVFDIEGFYRFMKKAKRFKTKIIAGIMFLKSARMANYLYKKIGIYIPSSYRERLE
KAKDIKEEIVKMSSQLIDDLKDIADGIHFMPLGNYPLIKRILK
>A0A382AII7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MHLIELYKKKDFVFSIEIFPPKTAKGMEKLKTTLEAFKSCTPDYFSVTYGAGGTSRENTH
ELAAHIHHDLDVPAMAHLTCVAHTVEEIDVVLSNLKNSEITNVMALRGDPTAGTKHFVQP
KGGYHYASELITAIREHSDFGIGAAGYPEGHVENPDKDDDRKHLHEKIAAGAEFVITQFF
LENTHFLRWRDQLRREGVNVPLVAGILPPSNWKATKHMSEMCGVSIPEDLAQALIKNETD
PEASREIGFDHVENQFEELLQEGVEGVHLYALNRLSTVERLGPILKDASGTISTPHL
>A0A383ESW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
CFDMDILRDYMLRLADFGILERTHFIIGIGPIASARSARWMNKNLFGVHIPEPIVTRLEQ
AKDSKAEGRKICVELIQELAGMDGVSGAHLMAPHGEQAAATVIRECGVLENRVA
>A0A381Y4Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
ILQRLQFQMSKIIAQPEQIQVSFEFFPPKTEKMEETLWNSVQRLAPLQPRFVSVTYGADG
STRDRTHRIVQRIHNETDLTCAPHLTCIGATRNDVMDVASSYWEEGIRHIVALRGDPPKD
ISHYKPHPDGFPYASDLVSGLLKIGTYDISVAAYPETHPEASSARFDLENLKRKIDAGAS
RAITQFFFDTDLYFRFRDRCVDHGIEAPIVPGILPITNFKRMVSFADTCGASVPTWLHER
FAGLENDPETRQFMAASIAIEQVETLKRDGVQEFHFYTLNRAALTYAICHALGLRPKKTN
SEKPTT
>A0A7W1JJ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MALAHARYEVLPTPSIEATVLEHVPKEVPLTVTASVSRGLEASLELVERLRGHGYAVTPH
LAARMIRDRTHLSELVDRLVGLGIDDVFVPAGDADPPVGDYPGSLGLLRDLTELGRPFAK
VGITGYPETHPSIDDDLTIQSMWDKREHATYIVSNLCFDAKVIRRWVERLRRRGVTLPVL
IGMPGPVAPAKLLAVATKIGVGESARFLAKNTSVFGRIATPGGYRPARLLNKVAPLFADP
AAGVDGLHLFTFNQVVDVEVWRLSMLGYQVPAR
>A0A7D7VFS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MTFPELYRNPSKPVISFEIFPPKTPEGKGNLLSSLEVLAKLSPGFISVTYGAMGSTRGNS
FEIASHIKDKLKIETASHLTCVGSSSAEIDLILKNLRERGIENIVALRGDPPDNRKKFTT
AHGGYSHANELVEHIRGFESENRNGRFGVAVAGYPEKHIEAPSLEKDIENLAKKIHAGAD
TIITQLFYDNRFYFDYVKKVRRAGLENPVIPGLMPILSMRQVLKITSMCGTTVPESIMKR
LEECERKNGDIGQVAIDICAEQAENLLSEGVPGIHFYVLNRASYVKSVLKRLGL
>A0A384CDN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ursus maritimus|TrEMBL
MDHPTPKVLPARPRGPSLGMWALEAGRVRFSVPPSISRNRAMVNEPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERHDRLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQITG
YLQKARRLGLKNILALRGGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFF
QFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNY
GIEQAVSLCQQLLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKR
REEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREEL
LKMWGEELTSEESVFEVFAHYLSGEPNQQGYKVTCLPWNDEPLAAETSLMKEELLRVNRQ
GILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVN
YHIVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWGK
LYEEESPSRMIIQYIHDNYFLVNLVDNEFPLENCLWQVVEDTFELLNQPAPEGETEAL
>A0A381UJN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
VKTNQKEINNKSLIKDFSIETTPNVYAKYGQFTEFLSEKNDVYVTYLPDEKSENVIETSK
KINEEGLTAIPHLPARTIKDNSELEKYIGSLSEIAGCNKILVIGGGSIQTGNIASSMQVL
KTDLLSKYNFVQVGLAGHPEGNPDISDKELDKAIIEKNMFAQNVDFKMYLATQFFFESSS
FEKWEAHLISLKNNLDIHAGIPGPATLKTLISFATSCGISNSIRFLSKQVLNISKLATSK
TPDKLIVDLAEYKQMNPSSKLAKLHFYAFGGIKKTSSWLNLITNSSLDIKSNNEFEPIKK
>A0A381UHF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MVEDLRKFNPPFIDVTSHSSTPEPYTNGKKVLKRKRPGTISICGIIQNRFNIDTVAHLIC
NGFTKEETEDALIELSFLGIQNIIAISGDGNPKKIVDDGKTINPNSLHLVKQIKDLSKGK
YLNEISNSSSIDMCIGVGCYPENHFFSNDFDKEINLLKQKIDLGATYAVTQMCFDNKKYF
SFVDKCRKENITIPIIPGIKILDKPRQIESLPRMFNINLPSELEKEASENIQHIREIGTR
WAIKQSEELINAGVPVIHYYLMNDTSCMLDILHHLHK
>A0A2I8DF10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp. AONIH1|TrEMBL
MSALKQALDDGRFVCVLEIIPQQSPARLAGLGRIVQRGHLAGWPLLPAFADRVGAHSDLS
PLEGVGALGDPAASLLHFSGKDRERADLLRQMAAMKTRGLNQLLLLSGDRLPGHDPGGAA
VRYLESVSALQIAREHGPDWLLGAALNPFKYREEEGGAQYLKARKKLLAGADFLTLQLGF
DAAKHVEAQAWMRAQHGMKPMLACVMSLTDKRAAALRAVPGVVITDTMRELLAREQDVSQ
ALAARRGIERLALQIVGLRLMGYAGAHVSGVHRLDELLLLEQALIAQRDRITSLAEWLEQ
WHASWRMPGAPQVGFTPDASAWELGRSDVTATRRERLRYALFSTMHRQFFSRRGWLSKAF
GWSMTRPIWQAAVAAHALHAVERMVKRPLVGCDTCGSCRLQETLYVCPETCPKGLANGPC
GGTRLNRCEFDDRECVHSVKYRIAKSADQLPVLEQVLIPCIEAADRYRSSWPAWFTQRRE
ETRVRPSACGSPELPP
>A0A381XTK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MESQKKYKPQFSFECYSPKTPEAVTYLQNVQLELAQLNPDFFSVTYGAGGSTRNMTFETV
LDIRDKTGVESVPHISCVGNWGDDIKNMLQNYIDNDIKRIVVLRGDLPSGTVGYGQFQHA
NELVEFIRKQTGDHFHIEVAAYPEFHPQAKSAKADIDNFKRKVGAGANGAITQYFFNPFS
YYRFVEHCEKLGIDIPIVAGVMPITNCTQLVRFSEGCGAEIPRWILKQLQGFGDDRESIF
KFGVDVVTELCDQLLSNGVPGLHFFTMNKSAASNLIWKNLGLDRRVIH
>A0A381PTV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKKCRISLEFFPPDTTDKLNQLIEQAKFFAGFKPRFVSVTYGADGSTQDRTHRAIDILKN
ELNLHIVPHLTCVGSTKEEIQSIANTYWLKGFTSVVALRGDKPDGYLAKDDQSSHYHFAL
DLTIALKQLHDFTIYTAGYPEVHPEAPSRKFDLDNLKQKTEAGAWEVLTQFFYNNDHFYR
YRDECQKIGITGQITPGILPISNFKTISSFATKCGSEIPKEYSDQFSSLNDQSSMSDLGA
ELAIKQIEDLRSNGVRKFHLYTLNRKKIIETVIRQAFD
>A0A382WCF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MRKRDFVLTAELSLAPNSDAKSIIEQARLLGPHVDAIQVTENQYGAIHMSPLAAASIVLG
ERVDPILQISACNRNRAALIGDLLGARSLGIRNVQLVQGKKMPDSYQPQPKGVKDVSVEE
LIATAKLINGDPDLAEVTDLLIGA
>A0A7X3RSR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MREIRPVRRNSRGKTVNFSEYKNKKKDAPFISFEVFPPKDDPEFEKLKDTLARLAEFSPS
IITVTHGAMGKGRKRTLEVASYVKNVIGTESACHLTCIGSSEKEIDLMLEGIEREKISNI
VALRGDIPEKDGENLLSRGAFQHANQLVEHIRKYEKGKPQRFSIAVAGYPEKHIESPSFE
EDIANLKKKVNAGADIIITQLFFDNSYYFDFVGRVRAAGIDVPVIPGLMPVLSSRQVIRI
SSLCGTDIPAPLKKKLENAGDDNRKAVEIGIAQCRDQVRELIAEGVPGIHFYVLNRTSHI
EKILKSV
>A0A382AET9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKYHSQLHKKLSDGVFVFTSETTPPDAASKEILLKKILPLKGVADAINVTDSPGAKVHMS
SLTAAIILAQNNIEPILQLTVRDRNRLALQGDLVGASALGVHNILCLSGDDPKVGDQPET
NPVNDINSLKLIETANIMRKDKKFPSGRVIEPPPNLRIGSAEVPTQGKPNLEKILKKINT
GVDFFQTQYVFDEKILKDYMKILDDSGILDKTSFLIGLGPFASAKSAKWMSDNLFGVDIP
KEIIKRLEQSKDQKEESKKICLELIQKFREIKGVRGVHLMGHNKEMIIAEIIKESRIS
>A0A2N8K5Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. M4_45|TrEMBL
MNGRTPYPVDCDGLRFSFEYFPPKNDEMEAQLFQTVTALSVFAPAFVTVTYGAGGSTKAR
SLTTVKRMIGEMEIGNTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGSV
YEPFPGGYENAAALVEALRARGDFEISVSAYPEKHPESPDVAADIDMLKRKVDNGATRAL
TQFFFDNDDFERYLERVRSAGIAIPIVPGILPINNLIQVQKFAGLCGARVPESIVSRLGP
LDDQPEGRFREAAHIAAEQITDLVRRGVSDFHLYTMNRPQLITAVCELMGYDPELAPAQP
ADTERPVRAVARA
>A0A5N8YT20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium AD-804-J14_MRT_500m|TrEMBL
MRRETASYFALWRESLAGKIIDTLIHQQTLSFEFYPPKSSDSLPSVWRAIRRLATFRPNF
VSVTYGAGGSSQTLTEEMVVDIHREGDVLPMAHVSCVSKSKVELYALLDRLGRAGIKNII
ALRGDAPTGTGKFTPVKDGFSHATELIQFIRANFDFGVAAACYPEGHVESPDLTADMEDT
RKKLDAGADFLITQLFYDNRHYFDFVDRARKMGISAPILAGILPILNVSQVRRFTSHCGV
RIPPYVDNSLSRIETDDEAVKDFGVGLATKQVQELWDNGVDGIHFYALNRSQSISRILDN
LGDLDFNRSHRPRI
>A0A0W0IP96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ICMP 3272|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A2U1TK20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brenneria roseae subsp. americana|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSDMEETLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWQSGIRHIVALRGD
LPPGGGKPEMYASDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRADLSYAICHTLGVRPAATL
>A0A084R8F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stachybotrys chartarum IBT 40288|TrEMBL
MHIKDMLLEAQSNGQPSFSFEYFPPKTAQGVQNLYDRIDRMYSLGPKFIDITWGAGGRTA
ELTCEMVAQAQTVYGLETCMHLTCTDMDVAQVNDALKRAYEAGCTNILALRGDPPRDQDT
WTATEGGFLYARDLVKHIRETYGNHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDLGASF
IVTQMFYDADNFVRWVGRVRERGIDIPILPGIMPIATYASFIRRANHMQCKVPQSWLDVL
EPVKNDDVAVRELGKQLVAGLCKKLLAAGIIHLHFYTMNLAQATRMVLEELTWAPSAERP
FKQALPWKQSKGLKRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPQSISDISKIFLRYLDQKLDSLPWSESPLSSEADSIKDDLVA
LNARGFLTINSQPAVDGVKSSHPVHGWGPANGYVYQKAYLELLLHPDLLTEVLNRVSKHP
TLTYYVITKAGELRTNAPGDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAYRLGMDW
AHCYDTNSPSRAVISQIMNSWCLINIVNNDFHDSRLLFEIFNDLEVPNLNTPVTASNGNV
NGAINGNGNVNGSALKQSTIAGN
>A0A2E4A8K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MHIRDIINKEQPSFSFEFFPPRSDEASTELLKTIKELECLNPSYVSITYGAGGTTRERTH
DLVEKILDSTCLIPIPHLTCVQHNEEEISTILKRYINKGISNILALRGDLPEDNNNYDRS
QDSFQYASDLVQFIKSYCKEQPDKNSELLGVGVAGFPEGHPNTPNRLKEMDYLKAKVDSG
ADYICTQLFFDNHDFFDFKERCLLAGINIPIIAGIMPVSSMKGLQRMAHLAAGSRFPAKL
LKSINRCNSNPEAIEKVGIQYATEQCADLLNNDVEGIHFYTLNKSKATRGIFESLGINKI
SI
>A0A4V1SB88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MHIQDILRASSAPTVSFEFFPSNTAEGQERLKETISRLADCQPDFVSITYGAGGSTRDAT
RQLVAHVKGSTRLNPVPHFTCVNHQRADIDAILAGYAAMGIGNILALRGDVPRNLPGHRH
QDDFCGHCADLVRHIRGFNASGAHPDSRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDA
GADYICTQLFFDNRHFHDFRERCALAGVRVPVLAGILPVTTFAGLRRMAELSGGTNIPGR
LLRSLLKYQDDPAAVLEIGLHHATEQCFDLMHSGVSGIHFYTLNQAAPVLEILKRLGRKD
RRTAPDALVAA
>U7TWX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum CTI-6|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPIDRELEIGD
FNYAKDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A3M1FJD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MTVTYGAGGGTRDKTFELVRYIKKDLAKKAVAHLTCAGHSKDEINSILQKYKENSINYIL
ALRGDPPKGESKFIPHPDGFSCARDLVSYIRENFNFSIAVAGYPETHKEAVSPQADIDYL
KEKVDAGAELIVTQLFFSANIYNHFIERVRKAGINVPVLPGIMPISNYKQLIRFTTMCGA
SVPAWISNKLEQIKDNRESVIKFGIDQAVSLCRDLLKSGAPGIHLYTLNKSAQVEEIVKI
LKKDALL
>A0A2A3H7S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Tue6028|TrEMBL
MALGSASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVVDTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDLDVGHFVD
KCRAGADYAITQMFFHPESYLRLRDRVAEAGCATPVIPEVMPVTSVKMLERLPKLSNAVF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A0R3NIQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium retamae|TrEMBL
MTEVTPAAFDGHRALHSPKISFEFFPPKTEEMERSLWETINRLAPLAPNFVSVTYGAGGS
TRERTHSTIARILKETRLTPAAHLTCVGAPKGEIDDVVARYHEIGVRHIVALRGDPTTGI
GTAYRAHPDGYQSSPDLIAGIKKRFPDIEISVSAYPEKHPESPTIDADIDTLKAKVDAGA
ARAITQVFFDNDLYFRYLDHVRARGIDIPVVPGIMPMHNFKQARSFVTRAGTTVPDWLAD
KFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A2D9LEV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MNTSFEFFPPKTEKGKENLVGLTKKLSRFSPEYFSVTYGAGGSTREGTLETCVSIKNIGQ
KACPHLSGIGAFRESISEVLDEYKEHGLTRIVVLRGDLPSGIGGLGDFPFALDLIKFIKQ
VEGNFSIEIAAYPEIHPDAESENSDFENFLDKVNAGADGAITQFFFEEEAYYKFVEKCEK
ERVSIPIIPGIMPIHGFEALVRMAKNCSANIPVWLKEGMEKYVNSEDQLSYGIEVITKLC
QKLLSFGAPGIHFYTVNREEPTSSIIKNLERS
>A0A7D5I6F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanolobus zinderi|TrEMBL
MSLTFKDKLESDHFLITAEISPPKGTDLSEALADAELIRDQVDALNVTDNQRAVMRMSPL
AVSRALQDAGHEVIMQLTCRDRNRLALQSELLGAYAMGIRNICVMTGDHTTKGDHPGSRP
VYDMDSVQLLDIVRRMREGYDLAGNVIDNPPEFTVGAVTNTNPSKLMQMMKLRKKAKSGL
DFIQTQAVYDTGQFEMFMEMTEDIEAPVIAGLIPLKSARMARFMNQNVPGINVPEEIIQR
IENAERPVDEGLAICAETARELKKLCRGIHIMPIGKHDRTPRILEMAGIRKNI
>A0A7C1M0D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon|TrEMBL
MAKRPAFSNLMKAIQDGHFVFTGELEPKKILNLDKIIHSAKEMKKTGRIIAANITDGPQG
DAYMSSMVPSYMVQEKANLEAVWQVTVRDRNRIALFGDVIAGAVLGLKNILTLTGDHTAL
GDHKKSRPVYDIDSTQFAEMLSMMIDDGTDYEGNEIKGGKIEMNFGCVANPNSDPREPEI
LKVGRKVEQGIDFIQTQTAFDIDQAKEFLKELEQFNVPVLLGVFPLKSHGIAWYFDNYIP
GVSVPKDLLKSLKTAEKENKGNKPGKYAAIDKINIEFFKPFIEEIKKTTKAAGIHCMAVE
YERLFESLLGGFPEYVK
>A0A6I5EIX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5469|TrEMBL
MALGTASTRTDRARTVRDMLASGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWEADVERFVD
KCRAGADYAITQMFFHPESYLRLRDRVAAAGCETPVIPEIMPVTSVKMLERLPQLSNAAI
PSVLQERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A7C1LMS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon|TrEMBL
KVEAGVDFIQTQTAFDIDEAKEFLKELEKYNVPILLGLFPLKNYGIASYFDKFIPGVSVP
KDLLSALKKAKKDFKEDKKKRNERIDQINIDFYEPFIKEIKKTTKARGIHCMAVHYERLF
GPLLKDF
>A0A7Z0WYJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus paralicheniformis|TrEMBL
MGFLEDIKSKTLIADGAMGTLLYSYGIDRCFEELNISKPEEVRRVHEAYVQAGADIIQTN
TYGANFIKLSRYGLEDETKQINEKAVRLARSAAGSAYVLGTLGGIRTFNKNSYSLEDIKR
SFREQLYLLLNEQPDGLLLETYYDLEEAREVLKIARKETELPIILNVSMHEEGVLQDGTP
LADGLKQLASLGADVVGINCRLGPYHMIRALEEVPLLEDAYLSVYPNSSLPSLVEGRLVY
ETDDEYFRESAEEFRNQGARIIGGCCGTTPNHIRAMAEAVKGLPPVTEKHVKIRKKAALA
VQNERTEPVLDDLAKQKRSIIVELDPPKQLNFEKFLHAAKELQSAGIDALTLADNSLATP
RISNVACGALLKQRLDMRSLIHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRLE
KKIACGADYFISQPVYSEEQLIKIHEETKHLETPIYIGVMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGNDKQKQAEEGLAIARSLLDAACDLFNGIYLITPFLRSDLTAELTAYIH
QKEKEKTNV
>A0A1V3NTV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioalkalivibrio denitrificans|TrEMBL
MKSQRAHEKVFSFEFFPPKSDEGAEKLRKAREALATLKPKFFSVTYGAGGSTQTRTLDTV
LEIQRDARFEAAPHLSCIGSTREHVREILELYRRNDIRHIVALRGDMPSGMRGDPGELRY
ANELVAFIREETGDHFFIEVAAYPEMHPQAPSYQKDLENFKRKVEAGADSAITQYFYNAE
AYYHFVDCCEKMDVTLPIVPGIMPITNYTQLARFSDACGADIPRWIRKRLEGYGEDMASI
RAFGEEVVTRLCEQLLDAGAPGLHFYTMNQSKATLAIWNNLGLKAG
>R5MRD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:1076|TrEMBL
MRVIDLIKSPEKTAFSFEILPPLKGTGIEKLYETIDSLREFDPKYINITTHRSEYVYREL
GNGLYERKRIRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREDTEYVLLDLQFLGITDL
LILRGDKAKHEQVFTPESGGYAHAVELEQQINDFNRGVFVDGSPIKAPVRPFSYGVACYP
EKHEEAPNMEQDIYWLKKKVEAGAEYAVTQLFYDNRKFFDFVDRVRQEGIDIPIIPGIKP
FSKLSQLSVIPKTFKVDLPQELAVEALKCQTDEEARQLGVEWCINQCRELIAHGVPSIHF
YTVGATESVRRVAKEIY
>A0A1A7R159|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gelidibacter algens|TrEMBL
MKVTEHIQQANGNTQFSFEILPPLKGQHINMIFDNIDPLMEFKPPFIDVTYHREEYVFKE
QENGLLKKHVVKKRPGTVGICAAIQNRYKVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VMALRGDAVKNETYFRPEKEGHEYANGLVKQICALNDGIYLDEELQNSSKTNFCVGVAAY
PEKHMEAPSLESDIHFLKKKIKYGAEYVVTQMFFDNQKYFEFVEKCRSEGITIPIIPGLK
PIATKKQLNLLPHRFHVDLPEALILEIIKCKDNTEVKQVGIEWCIQQSKELQKAGIPVLH
YYSMGKSDNIQSIASQVF
>C4YKV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida albicans (strain WO-1)|TrEMBL
MSTVAERIASLKPDEKFVSFEFFPPKTDSGFRNLLARLNRMSAFNPLFVTVTWGAGGSTS
EKSLDLAATCQNEIGITTVLHLTCTNTNKEVIDQALSKAKAAGVRNILALRGDPPRTEEY
WTPNCDFNGAVDLVKYIRENYGDYFCIGVAAYPEGHVDGSDTSSQNPQRDIPFLVEKVKA
GADFIITQLFFDVEKFIAFDKLLKEHDELKGIPLIPGLMPITTYKVFNRAAKLSHASIPK
EILKQVDQVCHDDNAVKALGVDILSEMIDQIDKSTTIKGYHFYTLNLEKAVASILDKSDV
LRQVLEGSSYATRFEDAVASDSDDEDEPEKASERDITLTKTIKPRRVSSINDNELTSSKA
LVGKALLNDKKVLVDISTGKGALGKDAIWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHTP
AEASTKWGTPESIADLTQVFINYLSGKVDVVPWADSSLSPETALIQEELFQLNEKGWFSV
ASQPAVNGCKSTDNIFGWGPRNGIIYQKSFIELFMPKEDWKKLLLKIELDKTVTYYVGNK
DGEIKSNLPIGPNVKLSKNAVTWGVFPSKEVVQPTVIDYESFKAWNEEAFLLWLEWARCY
KKNSKSFELLNSIYENYVLVSMIHHDFINENALWDLLLDE
>A0A0Q8XEX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Root241|TrEMBL
MSIVDPLAAPLFADVAGDIEVSFEFFPPKTEKMEETLWESIQTLSPLGPRFVSVTYGAGG
TTRERTHNTVARIARETAIPAAAHLTCVEATREEIDQVAEEYWAAGVRHIVALRGDPPRA
GEKFQSHPGGYENAAALVAGLKKLHPFEISVAAYPECHPDSPNATADIDNLKAKIDAGAT
RAITQFFFEPETFFRFRDDAAKAGITAEIVPGIMPVMNFASVQRMSAMCGTAVPAWMGKL
FEGLDEHPAARQLVAATLAAELCRKLYAGDVRQFHFYTLNRAELSYAICHLLGLRPKVGA
ELAAA
>A0A3N6XZM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium camelliae|TrEMBL
MPASDRSLVDALRDERPTTSFEFFPPKDDEGEEQLWRTISELEPLAPTFVSVTYGAGGTS
QERTVRITERIARGSSMKPVGHLTLVGQSTAEIESVLKQYLAAGVDHVLALRGDPQGGPR
APWEGHPEGMNHAIELVELAERMGGITVGVAAFPEGHPDAESLEACAEVLVAKARAGAEF
AITQLFFRASDYVELVERVRGLGCDLPIIPGIMPILNFGQVARMAELSGAAMPAEVLEQI
EPIAEDRAAVRAKGIELATQLCRDVLDAGAPGLHFMTLNRSKATREIFETLRAEGRI
>A0A0M0HKJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio nereis|TrEMBL
MGYTHASHIDALNQNIADLSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKTETGLIAAPHLTCIDATREELIQIADDYWHNGIQNIVALRGD
IPAGGGKPDMYASDLVQLLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFE
GLDDDPTTRQLVGASQSIDMIRILSREGVKDFHFYTLNRAEMTYALCHTLGIRPSAE
>A0A659KVX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E3356|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5B0E1N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas fodinaquatilis|TrEMBL
MSDTSIRKPAIRVSFEFFPPKSPAMEESLWNAVQRLAPLSPAFVSVTYGAGGSTRERTHH
TVSRILQETALAPAAHLTCVDASREEVDEVVRQYRQTGVRHFVALRGDSQNGAGADFVAR
ADGYRNGAELTAGLKSIDPDFEISVSAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNELYERYVERVRRAGIYIPIVPGIVPIHDFTKISRFCSSIGASIPQWLAQRFEGLEN
DPQTRSHVAAAVCAEQVLDLTRRGVSDFHFYTMNRADLVYSICHILGLRPDAAAGVEKVE
MAHEKAGL
>C4YQ60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida albicans (strain WO-1)|TrEMBL
MKISEKLTQAHKGSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALEKAFKSGCQNILALRGDPPLD
GSESTGDFKYAKDLIKYIHEKYDNHFNIGVAGYPEGHPEEEDEQKTLRYLKEKCDAGADF
IITQMFYDVDNFISWCSKLRKIGVDIPIIPGIMPISTYAAFIRRAKWSEIAIPQHFLDAL
DPIKDDDFLVRERGTELVSEMCNKLLQSGYVNHLHFYTMNLEKATVMILEKLNLIEAIKS
HDVVGGSELPWRKSLHPERSKESIRPIFWQHRKYSYISRTATWDEFPNGRWGDSRSPAFG
DIDLCASELLRQSPKKAFELWGLPQSLAELSGIIINYLKGDLKSLPWSDGPVGDDTKVIV
DDLIYLNQHGFFTMNSQPALNAVKSSEKVFGWGPKNGYVYQKQYLEFFCHKDVVSKLLDH
VEEFNVKGAESSSAFISYYAVDKDGNLSTNCKDDDINAVTWGVFPGEEILQPTIVEKTSF
LAWKDEVYRLFTEWAKIASSNLVEANQTQVDEFVQLMKKFGDEFVLCNLVNNDFVDGNST
LFDLIKRLNIDDLN
>A0A239YJM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium mizutaii|TrEMBL
MKIVDHIKNAKGKTLYSFELLPPAKGQGIQSIFQTMDELMEFKPPFIDVTYHREDYLYKQ
HANGLLERVSYRKRPGTVAICAAIMSKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTAGGHAYATDLLRQVVDMNEGSYLHEDIGSSEKTNFCIGVAGY
PEKHFESPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVTKCRENDIHVPIIPGLK
PLTTKKQLITLPRIFHLDIPEDLSDAVEACKTNADVRQVGEEWLVHQCKELIDFGVPVLH
FYTMSNPGPTKKIVEKLV
>R8NWT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VD136|TrEMBL
MKILDLVSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADIIQTN
TYGANEAKLRMYGLENQVTQINKAAVKLAKAAVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEKVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQLALHEAGTTQNGN
DVNGILTQLLDYGANIVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGCYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPAHIEGMKRVIANVTPVTEKQIVQRQQVVH
IQTKRASTHVTLAEKARKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGSATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIEEIYEATKHLEKPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMDGHETQESAIEEGIRISQELINAAMKYFNGIYLITPFLKYEITENLVKYVK
EKQEVKEGIN
>A0A7C9QV20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum aberrantis SpK|TrEMBL
MSPLPIAATRPVNVSFEFFPPKTEKMQETLWECIKRLEPLAPSFVSVTYGAGGGTRERTH
DTVVRIARETSLKPAAHLTCVGHQTGEVDDIARRYWDEGIRHIVALRGDAPEGSGKYVPT
PGGYAYAVDLVKGLKRIADFEISVAAYPEMHPDAPSAQFDLDNLKAKVDAGATRAISQYF
FDVDVYRRFRDKAAAAGINVPILPGILPVTNFAQVRKFSAACGASVPDWMAKLFEGLDDD
PDTRRLVAATVAAEQCRALAADGVSDFHFYTLNRADLAYAISHILGVRPQAK
>A0A7W1SIC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
MGTMLYARGVFINQSYDEINLRSPDIVRGLHREYVRAGADALETNTFGANRVKLAQYGLE
AHTAEINSRAASIAREVADREGGGNVLVAGAVGPIGVRLEPYGATSTEEARETFREQMQA
LADGGVDCFLLETFGDLLEIQQAIVAARDAAPNLPVIAQMTVGVDGRTPFGATPEDIALA
LDRWGADIIGLNCSVGPQTILESIERMAAVTKRKLSAQPNAGMPRDVGGRQLYMASPEYM
ATYARHLVQGGAKVVGGCCGTTPEHVKAMCEGLRPIRPRSGVRGRGTGGETGGVAKSPTR
ATAELSLPPTPDPIPFKDRSRFAAKLAAGTFVTSVEIVPPRGVDASRMLADTRTLKDAGV
DAVNVPDGPRAQSRMGALMTSLLIEQQVGIESVTHYACRDRNLLGMLSDLLGASAVGLRN
MLLITGDPPKMGPYPDATAVFDIDAIGLTNLVANLNRGLDPGGNSIGTPTQFAIGVGVNP
VAIDVAHEVKRFEWKVDAGAEYAITQPVFDPDQLERFLERASGFSSIPMIAGIWPLVSLR
NAEFMANEVPGVSVPDAVMQRMRRANEVSKEHALAEGIAIAREMLERVRPFVQGVQVSAP
FGKVQLALEVFEGVLEGGSGGGG
>A0A847AU79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierellia bacterium|TrEMBL
MKIVDKFKEKNPLISFEIFPPKADYPVDTIFNAIDELYNMDPDFMSVTYGAGGSTKDKTV
EISSYIQNRYNLTSIAHVTCISSAKSEISNILNSLEENNVQNVLALRGDYPKDSAIALPI
DGFKNSVELIEYFKRNSKLCVGAACYPEKHPDASNLNEDIDFLKRKMDAGADFLVTQMFF
DNELFYDFYDKAVQKGVNLPIITGIMPILNKNQINTIVNLTGNSIPKKFERLLTKYSNNP
EALREAGMSYAVSQIIDLLSWGVDGIHIYTMNKPSTARKILGSISAIRSVLTNESSIS
>A0A7W0DPY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces himalayensis subsp. himalayensis|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFWAPKTPKGERNLWNALRRIEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADSTLTPVAHLTAVSHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWIPHPQGLTYAAELVRLIKESGDFCVGVAAFPETHPRSSDEDTDVQHFID
KCRAGADYAITQMFFQPESYLRLRDRVESAGCTTPIIPEVMPVTSVKQLERLPKLSNAAI
PDSLKERILTAKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHPQA
>A0A7X8IYE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierellia bacterium|TrEMBL
MKLTRLFERGEFVITAEVGPPKGFHINHLVDEINTYLKGRVSAVNVTDNQSSVMRLGSLA
TCKVLQDQGLTTIFQLTCRDRNRIALQSDVLSAALLGIENLLLLTGDHTTLGDNPQAKPV
FDLDSVSLLHMVRKLEQGEDLAGNPLEGEPPSFAKGAVVSPCSDSVDAQLIKMEQKVKAG
AEYFQTQAVYEPEKFIKFMEKAKQFGVPVMLGIVIPKSAGMAKFMNENVAGITVPAHMIE
ELKKNKEKTKAGITGVEISARIIKECKDYCQGVHIMALGWESKIPDLLDLACL
>R0C891|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster bolteae 90A9|TrEMBL
MNTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTRDDVLLILEQLKEQKIENILALRGDRTADREPAGDF
RYAADLVEFIKNHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFRERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFISMMERYGDNPIAM
RDAGIAYAVDQIVDLAAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>A0A7L9BVZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetia bacterium|TrEMBL
MRIRELLSTGRPCFSFEFFPPKTDGGLEQLRATVRALRDLSPTFISVTYGAGGSTRDRTI
ELVSEIQRHYGVEVMAHLTCVGSTRDELAAVIDRLATAGIGNILALRGDPPKGDAEFRPV
ADGFRFASELVAFIRSQNREICIGGACYPEGHVECVGMDGARDLHRDLENLQHKVEAGAA
FLITQLFFDNSHYFRFVDRARAIGIGVPIIPGIMPITNVEQVRRFTQMCGATIPPTLLNE
LDRLKDDEDAVLSLGVAYATAQCLDLLNRGAPGIHFYTLNKSAATRTILTALRTLWPPAM
RPA
>A0A836QMV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
PPKMSPAYPRSTAVFDIDSVAMIRYAHRHLNSGLDFGGQLLGKHRDPRTHFTIGTGFEPE
ALNTDREFDKLDRKIDAGADYVMTQPAFRFEPLGALEPYRSRIPILVGVAVLTGLEHARR
MNEIPGVLIPDEIFDRLARAGSSAAQGEVGVEIAAEQVRWVVGNGWSGLYLMSPASHHPV
LEVLGSGLS
>A0A1Y5DJH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp. 31_11_sub10_T18|TrEMBL
MLKNKIRNKKSGILFYGLTPPKATNTEEQIKVITQKHIDRILPLEIDGLVLYDIQDESDR
TNEKRPFPFIKTLDSTDYANDYLNVLNLPIVVYKAVGKYDKENMSSWLEESKKSNSYSVF
VGAASDTQKSKMSIKDAYALKKDINSDLVLGGITIPERHTKKKDEHLRVFSKTDNGCEFF
VTQAVYDLHASKKFLDDYSSYAKENNKKIVPIIFTLTPCGSAKTLEFMKWLGIHIPELLE
RKLMESGNILDDSVKFSIAIFESLYTYGLQKGIPIGCNVESVAIRKEEIDASIELLNEVQ
KIMKRHK
>A0A4U6XQW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum tanaceti|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTAMGLSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKDE
YRDTEDSDVDDIEDFVLAVDLVKYIRKNYGDYFCIGVAAYPEGHADESHPQGQSFEHDLP
YLIEKVQAGADFIMTQLFFDIKAYEKFENVLREHPSGAFKNIILLPGLMPIQSYQMIKRT
TKLSHAKIPDSLMARLDAAKGDDEKVKQVGVDILSELVEQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDPQLDDEEAVIDDGPGIPVSIPAVQLNGLSPITPAARALSGRRH
SSMGSSDPHNRIIVSSASNPAYETTTAGLMASEPVNTRANTLAISEGVGAVGREATWDDF
PNGRWGDARSPAYGEIDGYGVSLHMSVTQAIRLWGTPKTIQDINNIFIRHIKGQLSAIPW
SEEELLPESNMIQQELLELNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVEL
FIPSSDWASLVARLNEVTDNTICFYAANAAGDFVSSDSSGGLVLEGTEASTNAVTWGVFP
GKEIITPTIIEEVSFRAWAEEAFKIWGEWSKVYGKGSESEALLERIRTEYWLVNIIHHDF
VERDALWKLLSGEKES
>A0A5M4AHE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prolixibacter sp. NT017|TrEMBL
MKVSDIITQSDKTVFSFELLPPLKGQNADKLYRTIEDLLEFDPKYINITTHRDEMEYRTL
PNGLHERRTIRKRPGTVAIAASIQYKYGVPVVPHVVCGGFTKEETENMLIDLNFMGVKNV
LALRGDKLKSENIFKPEPKGHAYASDLVKQIVDLRHGKYLDPELKNNTPMDFCIGVAGYP
EKHAEATNPDVDLLNLKRKVEAGADYIVTQMFFDNQKYYDFVDKCRAAGITVPIIPGIKP
LSRKNQVSVLPGIFSIDIPEEFAKEVRKCKNNDEAREVGTEWAIHQAKDLIAHNAPCLHV
YTYGISDNTRQIAKAVF
>A0A517PZA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia chilikensis|TrEMBL
MRISEIYRSGTFGLSVEIFPPKNESGDAELFRTLEELVRYKPAFVSCTYGAGGSTSKRTI
ELCDTIQKDLHSTATAHFTCVGSTREQLVDWLKEASEAGIGNIMALRGDPPKGEETFIPA
DGGLKYASELVTLIRENFPEMGIGVAGYPEVHPEALTPQADLENLKRKVDAGADAIYTQL
FFNNQHFYRFQERCAQAGIDRPIIPGIMPITEYRRIQRIMSMCSSEFPAELVGRLEAAQD
DLDAQFEIGVEYAIAQCQELIDAGVPGMHFYVLNRSQACKRIFDALGWHESVA
>A0A2D7WHT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spongiibacter sp|TrEMBL
MANRYSFEFFPPKTEAGREKLVATRNELNSLAPDFFSVTYGAGGSTRDNTRGIVLDAKAA
GIDVAPHLSFGGDEEEEVLALVEQYRQAGVRRIVALRGDIPSGMGATRLVYARELVEFIR
KHTGDHFELEVAAYPEVHPDAPSYEQDVAYLKEKLDAGANSAITQYFFNADAYFYFLDAC
EKAGIDKPIYPGIMPITNYANLARFSRNCGAEIPRWLARKLDGYGQDLESIAAFGEEYVT
EMCQILMEGGAPGIHFYTMNQVQPVKRMLESVKASHP
>A6EBG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. BAL39|TrEMBL
MKIVDHIKNAKGKTLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNKYRVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDSAFVPTPDGHAYASELLQHVVNMNNGRYLHDDIDNLEKTDFCIGVAGY
PEKHFESPNLDTDFKYLKQKVEGGADFIVTQMFFDNRRYKAFVDKCRENGINVPIIPGLK
PITNSKQLMSLPKVFHLDIPLELTEAIQSCKSEKEVKEVGIEWMIHQCKELKEMGAPVLH
FYTMGNPEPTRKIARAVF
>A0A7U9C9H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sporogenes (strain ATCC 7955 / DSM 767 / NBRC 16411 / NCIMB 8053 / NCTC 8594 / PA 3679)|TrEMBL
MHIKELFNQKNLVFSFEIFPPKVTSSIETIYETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTREDIDSIINELKENNIENILALRGDILKGKNIIGE
YNYAFELIRKIKENNNFGIAGACYPEGHIECESLEKDIKELKRKVDAGAEHLISQLFFDN
NTFYEFLNRTEQKNIKVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKEA
IRDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKGVAV
>A0A7X6Y834|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MENRFKESLLDKSTMSVTWELVPGRGAREPQQEFAVQAAEQAAKGGKVHALTITDNPGGN
PAMLADYLGMEVFQKGIEPLVHFTCKDKNRNQMESQLYAMDRAGVRNLLVMTVDYPVTGF
KGRPKPVFDLDPVHTLELIEEMNKGLEYPGMKGTIKHQPSDFFAGAAVSPFKATEAEQMV
QYYKLKKKLDAGAKFIVTQIGYDARKYHELMLMMKMLGYDVPVIGNIYLLPFGAAKVMNA
NQIPGCVVTDKLVADIDKERSDPDKGVGARLLRAAKMYAWMKGMGFAGVHIGGFNVKYEQ
VEYIIEKGEELSANWQDLIHEFDYPMPNGFYVFEKDEKTGLNKEQFTNRKNRPLDADTPF
VYSLSRFMHNLMFEPGKNLFGLMQKISAKAEGASWEKRFHRFEHMNKVRLYDCKDCGDCA
LMDLAYVCPMSQCPKNQRNGACEGSYHGWCDVYPNERKCVWVQAYARLKKYGEEEQLNSY
RVKPCNWDLYQTSSWINFYLGKDHSAERLGIKNPKANRPE
>A0A7V9J7K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MRIDEILRERRPVFSFEFFPPKTDAGEQNLRATLEALRHDDPQFVSVTYGALGSTRDRTI
DIVKWIKQELGIEAMAHFTCVGATVPELRETLDEIEAAGVDNVLALRGDPPAGEEEWRQT
EGGLLYSTELIELLTGSYGFAVGAAAFPEVHPQAESPDSDIRFLKAKQDAGASFLITQLF
YDNEFYFDFIGRARSAGVTVPIIPGIMPVTSFRNIKRITELCESKIPESFERELEAREEE
EDAVHDLGIAYATLQCMDLLARGAPGIHFYTLNRSPATRAILAALRAAQ
>A0A0H3EA59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum (strain PRL2010)|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIANTIH
GEYGIPAVAHLTALYSDEAKIDEALDMFEAAGVSAVLALRGDYIDGEEPVGRFNHASDLA
TYIHDRKPGLKVFGACYPEGHYSAASLDEDIGNLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGAKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGII
YASDQIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFTVE
>A0A7V3HBA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MKITEILKKKRTFSFEFFPPKDEKQSSDFFENLKELALLNPDFVSVTDTNYGIAKYKHLA
LSKLLMEKLNFNVILHLTCINNTRKELIEFLNKAIEFKIENILALRGDYSFSCDINARDF
SYAIDLLPIINKDFFSIGAAAHPESHPESSGLDEDIEFMKRKIDAGVSFFITQVVFDNEA
LYRFMEKMRKNNINAPLIVGIMPVSNYKMIENIEKKTGHISKPKEFLHIVENYKDKKEEF
YKYSLDFFTAQCEDLLSKGVNALHFFTFNKAKMPKEILKRLK
>A0A7X9A6W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MNNRFKESLLDPNTMSVTWELVPGRGAREKSQINAIAAAEQAAKGGKIHALTITDNPGGN
PAILADALGMDILKVGIEPLVHFTCKDKNRNQLESQLYSLDRAGIRNLLIMTGDYPVTGF
EGRPKPVFDIDPTHTLELIGEMNRGLEYPGFKGTIKHQPSDFFAGAAVSPFKGTEAEQMV
QYFKMKKKIESGAQFIVTQHGYDARKFHEVIQFMKLNNLNVPIVGNLYILPFGAAKIMNK
NQIPGCVVTDKLVAELDKERTAPDKGVGARLLRAAKMYAIMKGMGFDGVHIGGHNIKYEQ
VEYIIEKGEELSANWLDLVREFDYPMPNGFYLYEKDEKTGLNTETLTNRKGRPLDTPVQF
VYRLSRVVHSLIFEPNKNFFGLMRGVSKAVDGTGMEKYYHWLEHMAKVMIYDCKDCGDCA
LTDVAYSCPMSQCPKNQRNGACGGSFNGWCEVYPNERKCVYVKAYARLKNYGQEMQLDSY
HVTPCNWDLYQTSSWINFYLGRDHSAKRLNIPKVEKKKK
>A0A4R2GP19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronoflexus pectinivorans|TrEMBL
MPTAAQLIRDLKQPGFSFELLPPLKGNSIKRVYKTIDALKEFNPLFINITSHRDEVVFKS
IDNGLFEKKITRKRPGTVAVAASIQHLYGIKVIPHIICSGFTKSETEYALIDLNFLGIHD
LLLLRGDKSKNEKFYQAQDEGNKFAIDLIHQVNDLNKGVFLDSTQAEAFDTPFSFGVAGY
PEKHEEAPNMESDLYWLKKKADAGAEYVFTQMFFDNSKYYDFVKRCREIGISIPIIPGLK
PVTLMNQLTVLPKIFHTDIPEDFAKEIRKCKTDEQVVEVGIEWTTMQAKDLIANGVNLLH
FYTMMATESVRRVAKDIY
>A0A5E4T7P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea terrae|TrEMBL
MTQRSFSFEFFPPKTPEGAEKLRATRQQLFPLKPKFVSVTFGAGGSTQQGTLDAVVEIQR
EGVEAAPHLSCVGSTHENIREILGTYRSHGIRHIVALRGDMPSGMGEIGEFRYASELVEY
IRKETGDWFNIEVAAYPEYHPQAKSPRHDLENFARKVKAGANAAITQYFFNADAYFHFVE
DAKRLGVDVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLESFGDDRESIRAFGLDV
VTELCDRLLAGGAPGLHFYTLNAAGATQAIWKRLGL
>A0A536X4Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
KVHLSSLATAHFLVQSGIEPIFQMTCRDRNRLALQGDILGAASLGIRNILVLGGDDPKAG
DQPETKPVYDLDSRTLLAMAHRMRTENALPTGTKIDGPQLRLVLGAADVPLDPPPGWEPN
GLKAKIEAGADFVQTQFCMDVGVVRRYLQRLAYAGVRVPLLIGVAPVPSARSARWVREKL
YGTIIPDAYVERLERAADPKLEGRKICIEVLRELAVIPGVAGAHVMAPMNFAEIPVVITE
SGVAGRRLAHAVH
>A0A0J6FF77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccidioides posadasii RMSCC 3488|TrEMBL
MHVKEKLAHSEASGRPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPPREKES
WAPTEGGFRYAKDLVKYIREKYGNHFDIGVAGYPEGCEDEEDPETLMKHLKEKVDAGGTF
IITQMFYDVDIFLDWVKRCRENGIQVPILPGIMPISTYASFLRRSNWVKCKVPESWMEAL
EPVKNDDAAVKQIGKKLVANMCQKILDSGIRHLHFYTMNLAQATKMVLEELKLIPSYETP
LQKPLPWRQSLGLGRRDEDVRPIFWRHRHQSYVARTQTWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSIKDLSAIFIRFLEGGLDRLPWSESPITEETDDIKQDLID
LNNRGFLTINSQPAVNGMSSSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNP
DLTYYAINKNGELKTNTSDSPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRLGDDWA
KCHDARSPSRQLIQRVMDEWYLVNIVNNDFHKTHDIFDLFNDIVVKDLDVEATGIEEPTS
QPANTNPERQNGDAAQTKDISVATNGTSN
>A0A4R9JHJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira perdikensis|TrEMBL
MHISQILGKKQTTISFEFFPPKNEETSEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEQTGLTIVSHLTCVGSTKDEIREILKRYEKSGIHNIMALRGDPPKGQTEFQQT
ENGFAYAGELVGFIKKEFPEMGIGIAGFPEGHPSTPNRLKEIEYLKWKVDQGADYICTQL
FFNNNYFYDFVERCEIAGIKVPIIAGIMPITSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDSYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRKIYESLGIRNFDSIG
>A0A2A4TSA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MRFPSLYNGEKPVFSFEFFLPKAPKDMGRFRETVVELKRLSPDFVTLTYGAGGSERSQTI
ETAAMIKHEIGIDTACHLTCVVHTKAEIAELLNRIAGEGIENIVALRGDMPKDRDPIPVE
ERELPYAIDLVRQIKERGGFSLAVAGYPESHVEAVSPEEDLQHLKAKVDAGGEWIITQLF
FDNKAYFDFVARARAIGITNPIVPGIMPIATAKQTKRFTEMCGTSLPQSLLDGLNPIAED
KEAVTRFGIEYATRQCRELLEGGAPGIHFYTLNKSRATTTILENLRNT
>A0A831RY15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiolapillus brandeum|TrEMBL
METSDKDTPAISFELFPPKTEKGMEKLKTVVGELNHLNPEYFSVTYGAGGSTQERTFATV
DWLREQGIDTAPHLSCIGTDKEEILEILTRYREQGIHRIVALRGDLPSGSGLGGLGELNY
ANELVALIRQSFGEDFHIEVAAYPEFHPQAENALADLDNFRRKVESGAHGAITQYFYSAD
AYWRFLDDCKQRGIDIPIVPGIMPITNYSSLARFSDACGAEIPRWIRKRLEAYGDDLSSI
QAFGAEVVTALCRQLLEGGAPGLHFYTMNQSGSVLEICSGLGIASGASAT
>A0A6M4G0Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium yanoikuyae|TrEMBL
MTQTDRARHDAEGPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFVSVTY
GAGGSTRERTHNTVARIARETPLAAAAHLTCVAASKAEIDEVADAYWEAGVRHIVALRGD
PPEAGTAFQPHPDGYKGAAELVEGLRKRHDFEISVAAYPETHPDALSAQSDIDNLKRKID
AGATRAITQFFFEADTFFRFRDTVAAAGIDADVIPGIMPVSNFAAVQRMSAMCNTDVPAW
MGRLFDGLDQHPAARQLVSATLAAELCRNLYMGGVRDFHFYTLNRAELSYAICHLLGLRP
ASDGLKRPQVTVDA
>A0A3A0H800|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus gallinarum|TrEMBL
MSQLLKALQNNILVADGAIGTIFYSEGLDTCPEAYNLTYPEKVQRIHQSYIDAGADIIQT
NTYGANFEKLKVFGLEHKVKEIHQAAVRIAKNAANEDTFILGTVGGFRGIKQEDLELTAI
QYHTEIQVDTLIEEGVDGLLFETYYDLEELTNIITATKRKYNIPIIAQLTALNTNYLRNG
TEINEALKTLIASGADIVGLNCHHGPHHMKESFSHIELPDDAYLSCYPNASLLDIDNSEF
KYSDNAVYFGKVAQQLISEGVRLIGGCCGTTPEHIKFIKSSVAELSPITDKNVIPITKKV
KKQSNQSTIKQNLTDKVKARPTVIVELDTPKHLDTDKFFRNIKKLDEADIDAVTLADNSL
ATVRVSNIAAASIIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILTITGDPSK
IGHLPGASNVYDVNSKGLTEIALRFNQGINTDGDALKVNTNFNIAGAFDPNVRKLDGAVR
RLERKLESGMNYFITQPVYSAEKIKEVYEATKHLDAPFFIGIMPVTSYKNALFLHNEVPG
IKLSEEILSQFEAVKDDKEKTKALSLKLSKELIDTVHQYFNGLYLITPFQSVDYTLELAS
YSKTITSNKQEAIL
>A0A833GCU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bauldia sp|TrEMBL
AYVERVRAAGLDIPIVPGIVPVHSFPQVARFAERAGASVPAWLAQRFEGLDDDPTTRQLV
AAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGMRPASPAAAEAAA
>A0A7K0HRY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides distasonis|TrEMBL
MKVIDLINSSKSTAFSFEILPPLKGNSIQKVYNVIDKLIEFDPKYINITSHHSEYIYKTL
PDGSFQKINIRKRPGSVAIASAIQNKYGITAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQKTDIYHEHATDLQQQVNDFNKGIAIDGSAFEANETPFSYGMACYPE
KHEEAPNMDSDIFYLKEKVKNGADYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKPI
VFKNQLTVLPKIFRSDIPEPFATELRKCK
>J4QH60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia multivorans CF2|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLDAAPHLSCIGSSRDSLRAILDQYRSCGIRHIVALRGDLPSGMGSVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLTRFSEMCGAEVPRWIARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATKAICERLDV
>A0A0A3AT43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chelonobacter oris|TrEMBL
MSYAREIDALNQSLADLNGKLNVSFEFFPPKNENMEKLLWESIERLNVLKPKFVSVTYGA
NSGERERTHGIVKAIKQQTGLEAAPHLTGIDATAEELRAIAKDYWDSGIRHIVALRGDEP
KGYAKKPFYASDLVALLRDVADFDISVAAYPEVHPEAKSAQADLLYLKRKIDAGANRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLQKMATITNVKIPGWMVKMYDGL
ETDQVSRNLVAASIAMDMVKILSKEGVKDFHFYTLNRSDLTYAICHTLGVRPV
>A0A1U7HUA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroogloeocystis siderophila 5.2 s.c.1|TrEMBL
MLNNLNGTSLNSLRTAIIRGDFLVTAEVAPPKGSNPAQMVQMAQQLKSRVHAVNITDGSR
AVLRMSSLAASVILLQHGIEPICQVACRDRNRIGLQADLMGAYALGIRNILALTGDPVKA
GDHVDAKSVFDLESIRLLKLIHKMNSGIDCCDQPLTDGATDLFPGAAVDPQLASWSGLQS
RFERKLEAGAQFFQSQLITDFDRLEKFMDQIANGCGKPIMAGIFLLKSAKNAQFINRCVP
GVNIPQHIIDRLEQAQDPLQEGVKIAAEQVKIARDLCQGVHMMAVKREDLIPQILDLAGV
APVKKEPVMSMTT
>A0A549VG77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter youngae|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A3E1DFW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrotoga sp. SPKER|TrEMBL
MTNSKSFSFEFFPPQTQEGANKLAAARKQLAILKPTYFSVTFGAGGSTRERTLEAVQQIK
ADGYEAAPHLSCVGSTRENIRAILHTYKNMGIKRIVALRGDLPSGMATSGEFHYANELVS
FIRVETGEHFHIEVAAYPEFHPQAKSPRDDLLNFKRKIMAGANSAITQYFYNADGYFRFV
EECRKMGVTLPIVPGIMPIMKFSQLARFSDTCGAEIPRSIRKILESYGDDTESIQAFGLD
VVTQLCERLLTGGAPGLHFYTLNQSAPSLEIWKRLGL
>B1ZNX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1)|TrEMBL
MLPDRPIAELFATRRPVRSLEFYPPKDAAGVEALRATAHALRRMLPDFVSVTYGAGGSTQ
ERTAQVSSILRKDCGFTVMPHLTCVGHSQLELAALADGFHDHGFRNIMALRGDPPKGSAQ
FTPQPDGLRYAADLVTLLKSRHTDFCLGVAGYPEKHPEAASLDVDLTNLKRKVDAGADFI
TTQLFFDNTVYYRFVEKCRAVGITVPIVPGIMPVLSLHQIQRFTAMCGATLPKQLITRLE
VAAENTDVVETIGIDWALTQIRGLLANGAPGYHLYVLNRAKAALALTAGLAA
>A0A120FGQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium macuxiense|TrEMBL
MTETLSPASNGRHAPKTPNISFEFFPPKTEEMERNLWDTINRLAPLTPNFVSVTYGAGGS
TRERTHSTITRILRETALLPAAHLTCVGSSRGEIDEIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAGIKKRHADIEISVSAYPEKHPEAADFDADIDTLQAKVDAGA
TRAITQVFFDNELYYRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFDGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGT
QKAA
>A0A1H8K0D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sophorae|TrEMBL
MKEKIMNKETGILTYGMTPPKATHPPEKIAEISQKQCERIRDLDIDALILYDVQEEADRI
EQERPFPYLSTIDPTTYSNVFLNTLSVPKIIYRCVGKYSEAQLVDWIKSDLDQDRFSVFV
GSSSSQQEVKLDLTEAYRLSKQHNQDLTFGGVVIPERHMKKNDEHIRVANKVKSGCSFFV
SQATYDVEASKNFLSDYFYYCTNNGLEMVPILFNIAPCGSPKTLEFMKWLGISIPKWLEN
DLKYSSDVLDKSIRLTQKIFAELLEFGLEKGIPVGCSVESVSTRKVEIEASVQLVKDIKS
IIEKKLSPAAVI
>A0A354B1D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcales bacterium UBA10510|TrEMBL
MGLQQALDQGRFAITAEVMPPRGGDPARTLEAARALSGWVDAVNVTDGSRAVMRMSSLAM
CRLLLDVGIEPVLQLACRDRNRIALQADLLGAHALGLRNLLCLTGDPVRAGDQPKARAVN
ELEAVRLLQLVTQFNAGVDPVLGHLPDGPTALFAGAAADPQSPSWSGLRRRVERKKAAGA
RFIQTQMVTDAAALRRFVEEITAPLQLPVLAGVFLLKSAKNAAFINRVVPGVSIPQAVID
RLASAADPAAEGIAIAAEQVQTYRNLAQGVHLMAIKAEERIPAILELAGFAAK
>A0A1I4ZMK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium oleae|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICSAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIEN
IMALRGDAMKGHQYFEPTPGGHASAMDLVHQINDLGRGKYLHNDEEACDELNKFCVGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVTKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEELINEVEKAKNNEAVKQIGVEWAINQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A7V7VL85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHISDILSSRKPSLSFEFFPPRAAAAWEDLYQTIRDLEQLAPAFVSVTYGAGGGTRELTH
DLVVRIQQTTAIPPTPHLTCVGHSKAEVEAILERYAAAGVSNILALRGDAPRDQPDYDWL
RGDFRHAADLVAYIREFNDSGRHPDPRGFGIGVAGFPEGHPDTPNRLTELNFLKQKVDAG
ADYICSQLFFDNHDFFDFRDRCVLAGIEVPILAGIMPVTSLQGMQRMAELAAGARFPAAL
LRALERANTHPEAVERVGIHYAAAQCAGLLDNAVAGIHFYTLNKSHATREIYASLGLFPG
>A0A6I5ZG81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp. 135|TrEMBL
MRIAIYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFMPPRDAEGEARLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSIAELRALVGAYADQGIA
NILALRGDPPGDPLGEWIAHPEGVEYAEELVHLIDTLGDFHVGVASFPEGHHRAPDLEHD
TRNLVNKLRAGAEYSITQMFFDVEDYLRLRDRVQAADPEQGAKPIIPGIMPVTSLASIKR
MAELSGSVIPPKVVERFTKAAGDGPEEDRASVRAVGIDFATETAERLIAEGAPCLHFCSL
NFAKATSEVLGRLGVDVDAALHVPA
>A0A852UP32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium sandarakinum|TrEMBL
MALGRPSVLPDRVPTVRELLAAGDRSFSFEFFPPKNAEGERQLWRVIRELEALRPTFVSV
TYGAGGGTRDRTVEIVERLAHETTLTPVAHFTAVNHSLRELRHLVGRFAGAGVRNILAVR
GDPPGDPTGEWVRHPEGVQYAEELVRLIRQAGDFCVGVAAFPYKHPRSATVEADTEYFVR
KCRAGADYAITQMFFRAEDYLRLRDRVAAAGCDTPIIPGIMPVTQMSTIARSEQLSGAPF
PPEVAARFEAIADDPAAVRRLGIEHAVELCRTLLAEGAPGIHFITFNRSSATREVFRALD
IVPGAPAAPQAASLTA
>A0A2V6AK46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MNLLDELQERIVCGDGAMGTLLLDQGLPMESCLEEVCVSDPDRVRAIHRDYIAAGARVIE
TNTFGANAARLSRFGFEDRVGEFNRAAAKLAKETTAGKDVCVAGSVGPLGISALEADERR
IDRAHCFHEQIQALLDGGVDLIFLETFMDDVEMQIALEAKKSLSDCTTICSFACEPEGRL
ASGVPIIDAFRKLRGLGVQITGVNCMNGPHATVQLLQRIPLDGLLAAYPNAGYPKYTDGR
FIYHAAPDYFAQAAREMVAEGARLIGGCCGTNPRTIAAISKAIADLKPVKSKAVRVTAVT
PPPAKNVIAAPEESLLDKIAAGKRVIICELDPPKTLALEKYFRGAQELVRSGCDAITLAD
NSLAILRVSNLAVGAMLKERFGITPLLHLSCRDKNVLGLQSELLGMAALGMRHVLPLTGD
PARVGDHPGASSVYDVNSIELISIIGKMNEGFSHAGKSLKARTQFVIGCTFNPNAKSLDS
QVNRLERKVAAGAQFAMTQPVFDARLVEETKRRTAHLNIPIFIGIWPLMSARQAEFLHHE
VPGIIVPDGVRKRMADSSLENAAATGMEIAREIVFAVGSEFPGIYLITPFLHFDSTCELA
RFAREM
>A0A8J3G1I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algimonas arctica|TrEMBL
MAVNLEADSKLMRDNMHPATLNAGPVAKTARADRADVKVSYEFFPPKNEKMETALWDSIR
KLELHNPDFVSVTYGAGGSTRERTHRTVSRMVQETNLRPAAHLTCVGSDVSEINEIANDY
WDSGVRHIVALRGDPPEGIGRRYVPHAKGFAYGSDLVAGLKKVADFEVSVSAYPERHPES
PSWDAELDNLKRKVDAGATRAITQFFFEAETFLRFQDRVQAAGIDIPIVPGLMLQPNFQG
LKRMSDMCGVRVPEWYAFLFEGLNEDPETRNLLTSSLALELTASLFDAGVRHFHLYTLNR
AGLAVSVSRILGRHSLKRIKE
>A0A2V5JSD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIIQGSSPTFSFEFFPPKTPEAADILYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEQEIEEILLRYAKAAIGNILALGGDRPVGIAYDKSR
DSFQHAIDLVRFVRRFNESGAHPDRRGFGVGIAGFPEGHPATPNRLLEMDYFKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALANIHIPIIAGIMPITSIGGLKRMAELAAGARFPAKLL
RALERCQSAPKMVRRVGIQHALEQCDDLLHNDVAGIHFYTLNRSDATRLIFDSLGIPRHR
SAQASSV
>A0A401KHC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus awamori|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYNAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVEQLIDHLKEKVDAGASF
VITQMFYDTDNFIGWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSDWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A2V6NDE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
LALGGDRPHDIPYDKSRDSFQHAIDLVKFIRRFNESGAHPDPRGFGVGVAGFPEGHPATP
NRLIEMDHFKAKVDAGADYIVTQLFFDNRDFFDFRERCALADIHVPIIAGIMPVTSMSGF
RRIAELAGGARFPAKLLRALRRCENDPESVRRVGVHFALEQCHDLLDNNVAGIHFYTLNR
SDATRVIFDSLGIPRRRNAQAPTV
>A0A2V2D8T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MIEGNIADKFSSGKTVFSVEFYPPKTEEGARQILRTAKKLKDTASPDYVSITYGAGGATR
ELTVDYGELLGDIFGFEVMPHLACLGNSRADIEEILERFKRSGFRSVMALRGDPPKNAVG
FSPAPGGFLHANELVEFVREKFPDAAIGCAGYPEKHPEAESLEADIANLKRKVDAGADFV
VTQMFFDNSHYFNFVRKCREAGIEKPIVAAVLPALSYRQVMNFKSMCSSEIPEKLAEELL
SAGDDAELAAQIGIRWARAQIDELLSAGVPGIHLYILNRAQSALALYGAIRGS
>A0A1G6TXE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria marina|TrEMBL
MTAPQISFEFFPPQNLEASFRLWDTVQVLSPLAPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLNVAAHLTCVQASRAETLAIAESFALAGVTDIVALRGDPPKGEGRFQPHPDGFSNSV
ELIQALADTGRFTIRVGAYPDIHPEAASAQADIDWLKAKLDAGADEALTQFFFEAETFFR
FRDACAKAGIDKQITPGILPIENWKGARNFARRCGTRIPAWVEDAFGKATRDGREDLLAT
ALCTELCSDLIEGGVDKLHFYTLNRPELTRDVCHALGVTPKVALQNVA
>A0A1T4RJ46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium toruni|TrEMBL
MVNQTLATHTESELRVRYNDITRGVYFIGTTPPKTNTPLTEVEGIADRLVDRIKDLAIDG
LIVYDIQDEVSRTKKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSETDAFDEWL
NEAWHEYQVRDIVLVGSPSAKNEVSLPLSTAYQALAEHQNNFFTGGIMIAERHAKKGNEH
ARLIEKYQQGCNFFISQAIYDTQATIDILTRYAIECKQDGIKPQRILLTFSPCGSAKTLE
FIEWLGVSVPEATSLRILNATNPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRK
EEIDGSILLYKLLRASMDSHLAKHEFRTLQAKVSTAIASI
>V4Q995|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas chloritidismutans AW-1|TrEMBL
MTALNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKARAGADSAITQYFFNADCY
FYFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQA
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A7K3C955|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4912|TrEMBL
MALGTPSTWTDHAPTVRELLATGKTSYSFEFWAPKTAKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTREGTVRATQQIAADSTLTPVAHLTAVDHSVAQLRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSDDWDSDIRHFVD
KCRAGADYAITQMFFHPESYLRMRDRVVAAGCDTPVIPEVMPITSIRQLERFAQLSNASL
PSSLKERLLAAKDDPAAVRSIGIEFATEFCAELVSEGVPGLHFITLNNSTATLEIYENLG
LHRQS
>A0A834ZAM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetracentron sinense|TrEMBL
MQRVRSREEVDKMKVIEKIQAAAEGQVVFSFEFFPPKTEDGVDNLFERMDRMVAHSPTFC
DITWGAGGSTADLTLDIANRMQNMICVETMMHLTCTNMPLDKIDHALQTIKSNGIQNVLA
LRGDPPHGQDKFVQIQGGFACALDLVKHVRATYGDYFGITVAGYPEAHPDVIQSDGVATL
EAYQNDLAYLKRKVDAGADLIVTQLFYDTDVFLKFVNDCRQIGITCPIVPGIMPINNYKG
FLRMTGFCKTRVCYLLLIDLLRREEERNMKDLWQLTATACRKPQFYQKCVEVLNHGKEPL
EVNEIPSEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAI
LMNLGLIEEARISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPRGRWGD
SCNPSYGALADYQVCRNSHT
>A0A8D0L8A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphenodon punctatus|TrEMBL
MVNEALSTSNGSASSRSDGSSSGSESSKESSRCSTPILDAERHERLREKMRRRQDSGDKW
FSLEFFPPRTANGAVNLISRFDRMGTGGPLFIDVTWHPAGDPGSDKETSSMIIASTALNY
CGLETILHMTCCNQTKEMITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVEGFNYAVDLV
KHIRCEFDDYFDICVAGYPKGHPDAENYEDNLRHLKEKVSAGADFIITQLFFRSETFLKF
MKDCQAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVQGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSANSKRRV
EDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTSEESVFEVFTSYISGEPNRKGYKVNCLPWNDDPLAAETNLLKEELEKVNRRGI
LTINSQPNINGKPSTDPVVGWGPSGGYVFQKAYLEFFTSSENVKALLKVLKKYEQRVNYH
IVNVQGENITNAPDLQPTAVTWGIFPGREIIQPTVVDPDSFIVWKEEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNEFPLNNCLWQVVEDTFELLNSPA
>A0A8J6F5C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eleutherodactylus coqui|TrEMBL
MRRRADHKEEVCSLVVTMVNANSLDGSSASCSSTDNSKESSRCSTPVLDIERHERLRDKM
RRRVEAGDKWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGEPGSDKETSS
MIIASTAVNFCGLETILHMTCCTQTKEEITRHLQKAKRNGLKNIMALRGDPMGEEWEEEA
EGFNYAVDLVKHIRHEFEDYFDICVAGYPKGHPEAESYEADLQHLKEKVDAGADFIITQL
FFRSETFLHFLKACRAIGITCPILPGIFPIQGYGSLRQLAKLSKLEIPQEIKDVIEPIKD
NDAAIRNYGIDLAVSMCRELLDSGLVHGLHFYTLNREVATIDVLRRLGLWQEDPRRPLPW
AVSAHPKRREEDVRPIFWASRPKSYIHRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLK
SKSPRDQLLKMWGEELSSEESVFDVFTCYITGNPNHNGHKVTCLPWNDDPLAPETNLLKA
QLEKVNKRGILTINSQPNVNGKPSTDSVVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVL
KRYEPRVNYHIVNVQGKNITNSTDLQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFA
LWIEQWAKLYEEESPSRMIIQYIHNNYFLVNLVDNDFPLENCLWQVIEDTFQELDSPTEQ
>A0A397PFR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dichotomicrobium thermohalophilum|TrEMBL
MSVYDEMEAAAAQAGEEPDEIPVGFHPAVTPEMSVEERAGCLARNASIEIIPSTADKITD
FRELMPLGARVFVPFLPRAEFADCIPLAKRLRDEGMEPVPHIAARRLRSRAELTDTLAAL
REQVGLREVLVIAGDPEEPAGPFENSMSVLETGILEAYSVETIFVGGQPEGIPGVSGEAV
SDALDWKYAYAKQSPADFRLVTQFVLDPDNLMAWRRDLADRGIDLPLHVGVAGPTSLKTL
MKFAGLTGAKASFRAMRKYGVKLTRLSDTAVPDDLVYRLASDTEGAKVHGLHVYTFGGFN
SAVEWLSKWRAGAPQDCRKAGYATG
>A0A4V2DAU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter halotolerans|TrEMBL
MTKRIPISFEFFPPKTDVGAEKLRTVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREYSGDHFHIEVAAYPEMHPQAESFDVDIQRFIEKVHAGANAGITQFFFNPDAYFYFM
ERLDKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSKSIKAFGHE
VIVKLCERLIAGGAPSLHFYSMNQTEPTQQLVVDLGLN
>A0A5C3NE52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heliocybe sulcata|TrEMBL
MKISKKIEQAQKENKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
DLTSELVKTCQKIIGVETCMHLTCTNMPREKVDMALREAKQHGCRNILALRGDPPLGKDE
WEAVEGGFVHGIDLVRHIRKEYGDYFGIAVAGFPQHVRLPPDEFEFELKCLKDKIDVGVD
FIMTQMFYDVDIFIDWVKAVRAYGITIPIVPGINPLQTWNGFMKSTALARTTIPQALLDM
LEPHKSNDEKVREIGTKVVADMCRKIMAADIGIRGFHFYTMNLEKATRMLLEELQLVPRV
ETIKPMPWRQSLTPTRRNETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWINKTKEEAYKLWDHPTTYDEVAALFATFCRGKLAALPWSDSPPSPETTVIADKLA
KLNELGFFTINSQPAVNGARSDDRRFGWGPSNGYVYQKAYLEFFVSPELLAMLLPYIERD
PNITYHVINKTGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGRQ
WARLYEPDSPTRKLISDIMDSHFLMNVVHNDFQSEDAIFEPFFKAGGQLAASKATNSTVN
GH
>A0A059JAS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton interdigitale (strain MR816)|TrEMBL
MEKISDKIIALPKDAHYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEETKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFNHAVDLVKYIRKKYGDYFCIGVAGYPEGHADESHPEVQDPLNDLPYL
IEKTQAGADFIMTQLTYDIEAYKKYEALLRNHESGTFKNIPIIPGLMPIQSYHTLTRVTK
LSHAKIPPQILAKVEACKADDEAVKRVGVDIVSDLVESIKKIATPGHRGFHFYTLNLEKS
VSFILERCNLIPPSSEAPSDSELEFESAVYAASGASNGVATPDGRSTNVNRLRASSMNSQ
PHNRVIVDRLTRATDRSERSSTVHETSAQTAGYPALNPPNRNTALQISEGLGSLGREATW
DDFPNGRWGDARSPAFGEIDGYGPSLHVTAQVARKLWGTPTCRDDISNIFKRLLSGELHA
VPWSEGGAGEEGGLNPETATIKAELLKLVEGRGWWTLASQPAVNGVRNDHPVFGWGPRGE
GFVFQKAFVEFFCSGDDFHSKLKPLLQSYGHDEFAWFATNAKGDFQSSTSPETPTQPPTD
PTEVPFDADPLTEMDNGSVNAVTWGVFRGKEIVTPTIIEAVSFRAWGEEAFGIWEEWRRV
FPRGSPSEKLIREIKDDVWLVCVVGQRFGAGGDVGKESNEEDGKLLWKVLAGEQTK
>A0A7W3Q7C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter ciceronei|TrEMBL
MCEQTNAQAVPVEAPRRLLDGDLSIELSSDQVRDFSPSSSVLPQGSRVFLTHLTGKPLSA
QIDAAARLRDMGYLPVPHLGARNFNTADDYVRHVESHSRNGVTTALFVGGNPLISSGPLT
EAAQLLAHPVLRDSTIRHAFIGGYPEGHPAISQPALEDALRAKIALSSKVGLSVQVVSQF
AFDGAQMGRWAQKLHSDYPGLPVRVGLAGVTSLPKLIKFAVMCGIGPSLAALKRSGTGLF
NVLAEKDPGDVIEGIEATYPTPVAPLDIHFFPFGGWTKTLDWIAAARSR
>Q6CR34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)|TrEMBL
MRSNTKGKFDMVTVKQRFDELKGPCVSLEFFPPKTEPGKRNLLARMERMCALNPLFITVT
WAAGGTTAGKTLELATIAQRELNVPVCMHLTCTNMNKDIIDEALKAARDADIRNILALRG
DPAIGEEWSPDADTEFKYAVDLVRYIKKNYGDDFCVGVAAYPEGHCEGEADESLQDPMRD
LPYLKEKVDAGADFIITQLFYDVDKFLSFEKLVREKVSSDIPMFPGLMPINSHLLFNRAA
KLSHASIPQYILDRFPASVQSDDNRVKEIGVEILIEIIEQIHEKTNGRIKAFHFYTLNLE
RAIAQIVAKSPTLSKILEEEDEADDEWDSDVVLQDVDSLTLDDDNIKKRKRQSSASTDFP
LNTSIINKLNGMSHGNRVPSVPSRKVMISISQGTGVLGRNVTWDEFPNGRFGDSRSPAYG
EIDGYGPSLKVCNSTAYELWDHPVSLEDIKNIFIRYLEGSMKALPWSDLGLSAETAFIQE
ELIELNQRGYLSLASQPATNGSQSTDNIFGWGPANGLIYQKAFVEIFVRKEEWNQVLKPK
IESKNGEFSYYLGDYTGYFETNLQPKSSNAVTWGVFPNSEVVQTTIVEEESFKAWRDEAF
SIWIEWSKLFPKNTPENTFLRKMHRDYYLVSIVHHDFINPDGLWDLLLS
>A0A679GC42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas otitidis|TrEMBL
MSQDRRYSFEFFPAKTEAGHEKLLATARIFAGYKPDFFSCTYGAGGSTRDRTLQTVLQLD
GEIQVPTAPHLSCVGDSKAELRALLAHYKDAGIQRIVALRGDLPSGMGMASGELRHANDL
VEFIRAETGDHFHIEVAAYPEVHPQARNFEEDLKHFVNKVKAGADSAITQYFFNADSYFY
FVDRARQQGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYADDTASIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLLR
>A0A062ICU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 21072|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEHFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILAYVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQVGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEITRFSCQPTSKQLIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILREKLIPTVPLETRGTSSWKNWYLATEA
>A0A380KCD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus hyointestinalis|TrEMBL
MVREPLLERLSSSILVADGAMGTLLYANGLDTCHEYYNLSHPKEIAAIHKAYIEAGADVI
QTNTYGAQRHRLAVYGHEDEVKHINQEAVAIARREAGSDVYVLGTIGASRGLRQCELSLD
AIVDETLEQASYLLETGELDGLLLETYYDVEELTAVLTALRPLTDLPIITNIALHEAGIT
ENGRPLVEAFSQLVMLGADVVGLNCHLGPYHMIKSLKQIPLFAQAYLAAYPNASLLSYES
DSDGGHYSFSQNASYFEKSATFLVEEGVRLLGGCCGTTPDHVRAMKRAAKRLKPVTHKRV
TPLLDEEDFIQKTLKKDTLVDKVKREVTIIAELDPPKTLDIERFKSGIKALDAKGIAAIT
LADNSLARTRVCNLSLAALLKEGTNTPFLLHLSCRDHNMIGLQSRLLGMEVLGVENILAI
TGDPSKMGDFPGATSVYDATSFKLLQLIKQLNQGQGYSGASIKKATNFTVGAAFNPNVPN
LSRTGRLIEKKVAAGADYFITQPIFNLQTIKELALTVKTSPIPFFIGIMPITSYNNAIFL
HNEVPGIHLSDDFLARLEAVKDDKAACQRLALAESKKLIDEALEHFNGIYLVTPFMRYDL
TVELIDYIQEKEKRQKEIS
>A0A8C5BWQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gadus morhua|TrEMBL
LSFTWSGVNLPSHRYTDKGTMVNQVQRVDGSWQTSKSDSSGASNSGESSKESSRCSTPLL
DADRSDRLREKMRKRMESGDPWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHP
AGDPGSNKETSSMMIASTAVNYCGLESVLHLTCSNQSQETITGYLTKAKQLGLKNIMALR
GDPLGTDWEDEEEGFNYATDLVKHIRSEFDDYFDICVAGYPTGHPEAQSYAEDLQHLKEK
VDAGADFIITQLFFRADTFLKFLRDCRAIGITVPILPGVFPIQGYQSLRQLVKLSKLEVP
EEIMEVIEPIKDNDAAIRSYGIHQAVEMCRVLLDSGAVPGLHFYTLNREVATTEVLRQLG
LWIEDPRRPLPWATSANPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAF
GELNDYYLFYLKSKSSKDALLKMWGEELTSETSVFEVFTSYITAQVNRGGHKVMCLPWND
DALATETNLLKDELEKVNRRGVLTINSQPNINGKPSSDPIAGWGPAGGYVFQKAYLEFFT
SSENVTALLKVLKKYEPRVNYHIVNVQGHNMTNAQDMQPNAVTWGIFPGREIVQPTVVDP
VSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQVLD
DMFELLDAPPEVVGDGALAPVALASKLGNETTFRRRFIN
>A0A1G0YWZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_52_8|TrEMBL
MPGSGIQFEMTFEERRNRFKERLDSGSFFALLEIPSPSRKVELQTAVSRISEMAETAANV
EGLSVSLAFTDKSKFSDSWNVAEFATALCPNNRDNHVIYISGRESSLDNMLDTLKLCGAA
GFWNLVPVSGDAVPGEDAKATMSHRFTEGIHLLNQIGTIQKNPFFPGCPVNPFKYTPDDM
LAQYYKLIKKLNQGAGFLVTQFGWDMMKLQELRWYLNCRGLHYPSIARILVMSPEHADNI
LAGRMPGVPISPDFRAILEREVKLSGRQFESAQWRRLQIQAAGCKLLGYSAVQVAGLENA
SQVRIACKQIADALLEFRNFEEWRDAYQEHMSKIEMAPYPYRFYMFEKLFSQAHPETAPR
MKDIALRPCSGGERFNYKLSRFLFSHANRQLPDEHLISKKILVGCKRCSYCRLPLTHYLC
PERCPKGLANGPCGGTQADGSCEVSDNECLHARHLRLALLCKDGDSLEEKYIKPAEKI
>A0A1Q7ZTP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon 13_1_20CM_2_51_12|TrEMBL
MQGRVDAITIPALRNGEDDPSYPAGFRVTPQTRSLASAVIVRKTGAEAVPSLTCRDFRRS
DLALVPSLFKKGLDNFLVVFGDPYPGQRIEDYDFRKTEDLIRGVLSVFDGQRPCIGAVTN
QYAEDQERETSRTLRKVDAGADYVVTNTAFDDDLVLRHVDRLRSRGLKAPIFVQVSIPSG
LKNLLFVSQKFGIPVPEKVRQTLSRNPIGGGIRIAADAYTVLRSEVNGIHFSYLHRSHNP
IPAYTHLLDAIQTDGQLTVSIQAALRH
>A0A6N7M946|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaeta sp|TrEMBL
MDGSLFGYAIFYKLEKKIRAGADYIITQLGFDARKFIEMIRYVRQHLKLSIPLIGSVYVL
SSGAARFMQRGEVPGCYVNQELVSKLSQEAKAEDKGKGTRLERASQQVAILKGLGYNGAH
IEGLNLRSADVKLIISRANEIGDNWRDYLPDFGYASDNPFYFFQDGESFTPPKEGESPVL
RKTRRRAIPSLTFWATRVLHKLFFVKGTAGYKFMRAFSRFTVKRKALYHFFTFFERLVKR
MLFDCRHCDDCALFEMYYLCPEARCPKGMRIGPCGGSRVNGRCEVFEEQYCIWERVYWRA
KNRRECDKLKYIINPRDWKLYETNSWVNYFLGYDHSGVETEIPEKIKD
>A0A2E6U238|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MTSISFEFFPPKSEAAAEKLWQSIGRLAPLRP
>A0A519YQC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp|TrEMBL
MPTASQHRASRDGYRPIRVSIEFFPPKTDEMEQILWKSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETGLKPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPQDGVG
TTYRPHPGGYAQTADLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFENDIYLRYVDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLDNDVDTRRLVAAAVAAEQVLDLVDHGVNDFHFYSMNRSDLVYAICHVLGLRAQAPKV
AAKAA
>A0A5C7NTD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MMVRVSNFPRVSFEFFPPKTPPMAEQLWATIRALEPLHPQFVSVTYGAGGTTRDTTFSTV
RRIAEETSMHPAAHLTCIGHSRGEIDDLLRQYWDAGIRHIVALRGDPPPGESYRPHPDGY
AYAADLIAGIKRIADFEVSAAAFPESHPQAQSSDADLENLKRKFDAGADRAITQYFFNNH
VFLTFLDRARRAGIDNAVVPGILPVTGYAQVVKFSKMCGASVPSWLHDLFDGLDDDPETR
KLVAAMVATEQCRALMADGIDQFHFYTLNRADLIIGICRRMGLKPAPAPGIRASLSSGTP
PMQRDPQMPD
>A0A062IJD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 21072|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A2E8AIF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MMDISFEFFPPSSDQAETVLWESIKLLEPLNPDFVSVTYGAGGTTRDRTHNCVKKIIEET
NLEPAAHLTCVNSTKDEIKEITDSYKKIGVKHIVALRGDMPNFLDFEPHPKGYKSSIDLV
KNLSQQDFNVTVSAYPEKHPDALSLDQDIEFLKRKIDAGATKAITQFCFDFQIILAYRDL
LQKHNINIPIIPGIMPTTNFKGIQKMSKQCSTSIPKWIEKKYNGLEDKLDERKKVSKEIA
VDFCQKLISNDFRAIHFYTLNQSELTLSVCQSLNISDE
>R6JAM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia muciniphila CAG:154|TrEMBL
MKLSELFPQKRVLSFEVFPPKRTSPIGTVYHALSALQGLNPDFISVTYGASGGAGTSDTL
NIASSIKKDYMVESVAHLPCISLTKGNVLELLEQFRRNGIENILALRGDLPPDREPCRDF
TYASDLISFIKEQGNFHILAACYPEGHPESKSIVDDIRHLKTKVEAGADHLISQLFFGND
IFHAYREKLDLAGISVPLEAGIMPVVNKKQIERMVSLCHVHLPKKFIRMMERFEHNPIAM
RDAGIAYAVEQIIDLVAQGVDGIHLYTMNNPYVAGRICEATASIIRN
>A0A2D6T121|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSDPGASYPILPGHTSGGRLERVLRSGRFAVTAELNPPDSADPEDTFERALVLSRVCDAI
NATDASGANCHMSSVGICALLTRAGYSLVMQISCRDRNRIAIQGDVLGAAAMGVSNVLCL
TGDGVEAGDQPGAKAVFDLDSISLLETIRCMRDESRFLSGRAITSPPRVFLGAAANPFAP
PFDFRPLRLAKKVAAGAQFIQTQYCYDVARLKDYMKAVRDLGLDERCYVLVGVGPLASAR
AARWIGTNVPGVHIPESTIARLEGAADQKAEGKRICIELIQQIREISGVAGVHVMAYRQE
HLVSEIILESGVLEKRRPGYSEKNPTQGA
>A0A343JF99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium isatidis|TrEMBL
MKTCELFKVKRVLSFEIFPPKRTDSVNIIYDTIEKLKGINPDFISVTYGAGGSESSSNTL
KIASDIKNKYGLESVAHLPCINLTKGEVLKMLDDFKKAGIENILALRGDVNTRFILKNDF
KYASDLISFIKENGDFNIIAACYPEGHFESSTIIEDIRNLKRKVDAGANQLITQLFFDNN
YFYSFRERAAIAGINVPIEAGIMPVVNKKQIERLISLCRANLPKKFLTIMTRYENNPEAM
RDAGIAYAVDQIVDLIAQGVDGIHLYTMNNPYIAHRIYEAINTLLVA
>A0A2E5BM21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MISLGDRFRGGDRVRVSFEFSPPRTDEAEVKLWDAIERLAPLEPAFVSVTYGAGGSTRER
THSTVKRIVQETKMKPAAHLTCVGASQAQIDKVIQGYWDVGVRHIVAIRGDMPDMEGAYR
PHENGYQTTADLVKGIRAIGDFEVSVSVYPERHPESRSFEHDLDLLKAKIDAGATRAIAQ
FAFETEHYERLLERVAKAGIKIPIVPGIMPTTNFKGVERMAARCGATVPAWLRAYYDGLD
DDLATRRLIAATVAAEQVHDLERLGFRDFHLYTLNQADLTYAICHILGFKPKEAAPSEVQ
A
>A0A519X9Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp|TrEMBL
MPTASQHRASRDSYRPIRVSIEFFPPKTDEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMIKETSLQPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPQDGVG
TAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEAPTLDADIDALKAKVDAGADL
GLQG
>A0A3Q8CYR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus hordei|TrEMBL
MTTFNYSLELLQNSSISELATLQKLDPEFISITYTNHALSFFETTFTTALTLRKTTHIKT
VIHLPATSFTKKELTTLLAELDCSPIDSVLVLSGDQKINKKSIYTSALELTRFLGNELPH
LNILCSCHPETITSKVDLQKEIDLMKAKESAGCKIFISQIFFDNTSFVKFVKYCRAAGIK
AQIRAGIMPIINKNQVSFVEKVLKIQLPHSFKNIENNTDLRKVGIRFALSQIKILKDKGI
ANFHFFTMNDLETIKILTDGVL
>A0A1F4C1A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_65_24|TrEMBL
MPGASERFGTSALERCLQGGDFVVTTELTPPVSTDPAPFVARALPLKGLATAVNVTDGAG
AKAHLCSLVASYYLLKNGIEPILQMTCRDRNRIALQSDLLGAAALGIRNVLVLSGDDPKA
GDQPEAKPVFDLDSTALLSIAHRMRARRELPPGTAIAGKAGFVLGAADAPIDPPPGWHPK
SLIAKADAGANFVQTQFCMDMDVVRRYATRLLELGIAQRLPILIGVCPIPSARSARWMKD
KLYGTIIPDEMVDRLEGAAEPKKEGREICIEVLRELASIPGIAGAHVMAPQNPSAIPDVI
GESGVTALKRAPMP
>A0A2E4XPG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MVLTPTVSFEFFPPHTPKAEEQLWTVMNKLSPLGPAFFSVTYGAGGSTRSRTERLVERVH
NALAVPPAAHLTCVGATRDEIDTLAQQWWDSGIKHIVALRGDPPKGELQYTARPDGYANA
AELVSGLRKIADFEIYVAGYPEMHPDSADLSADLDNLKRKVDAGADRVLTQYFFDNALFY
RFRDAAVSAGIDIPIIPGILPVTNFARVVEFSEKCGTSVPTAMAQQFEGLDDDPETRSLI
AASTAIEQCEDLLANGVSAFHFYTLNRAALTYAICWRLGVRPVGENGTSAHAA
>A0A2E8R2G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MAESESIFDNPSALPSARLGEAVCAPALSDISVSFEFFPPTSDKIAEQLWNAILRLAPLG
PGFVSVTYGAGGTTRERTFDTVERIMRDTALTPAAHLTCVGDSRGRVNDAARRYWDAGVR
HVVALRGDPPEGAEKFEPAKGGYAYASDLVAGLKRVADFEISVAAYPEVHPEAASIEADL
DNLKRKIDAGASRAMTQFFFDVDLFLRFRDRASAAGIDVPIVPGILPVTNYGRLVDFSAR
CGASLPGWLARLFDGLDDDPDTRRLIAGWVAIEQCRRLTAHGVRDIHFYTLNRAELTRAI
CHALGIRTAQPLPEAAQ
>A0A7K3QMP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces bauhiniae|TrEMBL
MALGTASTRTDRARTVRDILATGKTAYSFEFYAPKTPQGERNLWNALRRVEAVAPDFVSV
TYGAGGTTRATTVKETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEILPVTSVKMLERLPKLSNALF
PPELKERILSAKDDPAAVRSLGIDFTTEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A7X7KKR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MRDAFLTRLARSPMVFDGAMGTMLYGRGVFINACFDELNLTRPRLVQEIHEEYAEAGADL
IETNTFGANPLRLRGYGLADKAGEINRAAARLAREAAGEDLYVGGSLGPCLQSGQVWHDG
LAEEIRQAYAVQVAALAEGGVDVLILETFTHPDEMLAAAAAARATGLPVLASFAVNEAGE
SALGVSAVSLVQLLQNSPDVDGVGLNCGTGPGPLYEIAEDCLPLCSKPFFVMPNAGAPRL
VDGRMIYMTSPEYFATYARRFIEIGVRAVGGCCGTTPAHIREAASTVKCLSGVKRHLEVK
AYVQEDARVQPVPAAEKSRLARRLLAGERVTSVELLPPRSSDLSGFLAKAKACRDHGIDA
VNIPDGPRASARVSPMIAAVELQRQVGIEAVLHYCCRDRNLIGMQSDLLGGFAAGLRNVL
IITGDPPKLGEYPNATGVFDVDAIGLTQAASNLNHGMDIGGTPIQPQTAFFIGVGANPGA
LSMDTEVARYHAKVRAGAEFAITQPIFDPEALLRFLDRVEGEGSRLPVLAGVWPLVSYKN
AEFMRNEVPGVTVPDAVMARMAECRTKEDGLRAGIAIAREICAAIADRVAGFQVSAPFGR
VELAFEVLH
>A0A3A9K4U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipaludibacillus neizhouensis|TrEMBL
MEFLEKIKNNILVGDGAMGTLLYQHGVDGCFEELNISAPEKVSHVHRLYVEAGSDLIQTN
TYAANSLKLRRYQLDHRVEEINGAAVALARKEAKEETFVFATIGGIGSVHLTEYEPDEIN
QSLKQQVDILLKTDVDGFILETFYDFQELLEIVKYVRKNTNKPIIAQVTLGDIGVLQGGT
PLADALLLLEAEGVEVVGLNCRMGPYHMLRSLEEVPLLTDSVLCVYPNASLPNVRDGKFF
YQSNPSYFADMTEPLVKEGVHLIGGCCGTTPEHVQAIRGAINNLHLQPVKDKSHRVKEPK
RKEVVKVASNRVLERIPEMPLKRRSVVVELDPPKALSATAKFLEGAAAIKDAGADAVTLA
DNSLASARIDNLALGSLMKQHSGARPLLHVACRDRNMIGLQSHLLGLHTLGIQDVLAITG
DPAKVGDFPGASSVYDMASMDLIRMMKQLNEGLSFSGKDLGEKTSFTVAAAFNANARRLD
REVTRLEKKIEAGADYFMSQPVYSEEQFKDIYEATKHLPVPIYVGIMPLVSSRNAEFLHH
EVPGIKLTQGVRDSMAKHGGDREASQREGLAIAQSLVDAAVEYFPSIYLITPFLRYEMTV
ELTKNIMKANKSFDITAK
>A0A031K1V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium resinovorum|TrEMBL
MGISGYPEGHPDIDKAKLAQAMKDKLAALAEQGKQAEIMTQFAFDADAILLWLERIRQDG
VTTPVRVGIPGPASVKKLVRFAARCGVGASAKVMMKYGTSITKLLSQAGPEQLIENLAER
LDPALHGEVMLHFYPFGGLVDTANFINRHYSK
>G2PVM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldicellulosiruptor lactoaceticus 6A|TrEMBL
MKKNFREFLKEQSTVIFDGAMGTELLNRGFSLDFPLEWANVTRPELVKQIHTDYILAGAS
SIETNTFGANECKLKVFGFENEVERINRSAVRIAKETADDKVYVIGSVGPLGKPVGSGFE
IDDRRAKEVYKRQLYFLLDEGVDAIIFETAASTHEVQIAIEALKELNDEIPYIIQFSFTK
DLSTIYGEDIYRVIEFLKSTDADIVGLNCGNGPQKTLEALKIFSQNLKGPFSVQPNAGYP
QLVQGRLVYSTSAKYFASFVPEYIKLGAKVVGGCCGTTPEHIKAIKEKIKEFLPSIEVEV
VERREEQKAVLKDTPSELSQKLGKKFIFTVEISPPKGIELEKTKEGVKLLKEAGADTVNI
ADSPMARVRISPIALAHILKEELGMESILHFTCRDRNLISLQSELLGAAALGVKNVLALT
GDPPSIGDHPQAKPVFDVNSEGLVLILSRLNNGTDYMGNPIGKATNFTIGVALNLNADDL
VKEIEKLKHKIENGAHFIETQPIYEPETLERFFEKVDFKLPPILGGILPLRSSRHAEFLH
NEVPGITIPDKIRERMRSSKEPAKEGVEIACEIVEKIKHMVSGIYIMPPFEKYEMAAEII
KMFK
>I4A3M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfitobacterium dehalogenans (strain ATCC 51507 / DSM 9161 / JW/IU-DC1)|TrEMBL
MENRFKQSLLDPNTLSVTWELVPGRGAREKAQESALLAAEQAAKGGKVHALTITDNPGGN
PAILADYLGQEILKLGIEPLVHFTCKDKNRNQMESQLYALDRAEVRSLLVMTGDYTVSGF
KGRPKPVFDLDPTHALELITQMNQGLGIPGPKGMSYHQTSDFFAGAAVSPFKGTEAEQMV
QYYKLKKKVASGAQFIVTQLGYDVRKIHEVLQFMKLNDLNVPLVGNIYILPFGAAKIMNQ
NQLPGCVVTDKLLAEIDKERTAEDKGVGARLLRAAKMYALMKGMGFAGVHIGGHNIKYEQ
VEYVIEKGEELSKDWMALIPEFDYPMPNGFYYYEKDPKTGLNTTTPVNRKNLPLDAPVGV
AYSGMRMMHSMLFTPGKNFFPVMRKIYKGRKDNRKHGFEHLAKVITNDCKDCGDCAMFEL
AYLCPMSQCPKNQRNGACGGSYQGWCEVYPNQKQCIYVRAYARLKKYSEEGDLDSHHIPP
ANWDLYQTSSWSNFFLGRDHSGEILGIPTPEEEEKAKSVDSTKQDVSK
>A0A7V4LZZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MREKPGMQANLSEALKAGSFALTLELVPDEKGASRTADIAQSFAAAAAEAGRTIHAFSLT
DNAGGRQGASADAAALELLRRGLCPLVHVTCRDANRLAIMSRIRGLRDAEVRHFFIVTGD
YPADSPQGRPAAVFDLDSVQAIRLAKSVAPDIFAGAAVSPFKETEAELMGQFFKMERKAA
AGADFIICQLGYEMRRFLEAKAYLEARRLDIPLLGNIFVPTSASARAMNFGRVPGCVFPD
DLLIEFEKAAAAPDKGRSFRLELAASMLAVFQGAGFSGAHIGGFGLKPADLSHLLARGAE
IGRNWPEALGHLSRLSPSRRGFYAFSPPVAGRTPLEAAPALQPGRSGRSPFYAVMRVVYR
LIFDPRSAGFRLMRSFYRVVDSCKPLARLFHGLEWCMKFALFRCQDCGDCALHDMAYCCP
QAKCFKHQRNGPCGGSKGGSCEVDPDTPCAWHLIITRLEERGRLGAVEDVCPPADWSKKE
GRGPRKIVREDQRQ
>A0A7Z0DB65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naumannella cuiyingiana|TrEMBL
MPTTPTRAATIAELLAEADRPLYSFEFFPPKDAEGEQTLWRTVRELEPLRPDFVSVTYGA
SGSTRERTVRVTERVARDTTLRTMAHLTCASQPAADLRRTIGAYAASGLRHVLAVRGDPP
GGPTAPWHPHPQGLANATELVELVASLGDFCIGVAAFPDLHPDRRDADLDARVLIDKARA
GASFAITQLFFDAEAWVRLVDRVRSAGCDLPIIPGIQPVTNLGQVKRFAELSGAELPSRV
VDRLNAVGDDPAQVRRVGVDIATELSERLLEAGAPGLHFFTLNRSRASREIFARLA
>A0A7K8ZV75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grallaria varia|TrEMBL
MVNETPQSCSGSSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCHQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYRVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6N4XPT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium fistulae|TrEMBL
MLSIFNIQFRYNMKITDHIKKANGKTLFSLEVVPPQKGIGIEDLYANIDPLMEFKPPFID
VTTSREEYVYIDKGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKDETEY
LLVDCMYLGIDNVMALRGDAMKGHQYFEPTQGGHASAMDLVHQINDLGRGKYLHNQDQIC
DEHNKFCIGVAGYPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAR
EMGITVPIIPGIKPIATKKHLKILPQVFKIDLPEELIAEVEKAKNNDMVKQIGVEWAIAQ
CRELLDFGVPVLHFYSMGKSDNIKKVARELF
>A0A2E5LFH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacteraceae bacterium|TrEMBL
MKKDLKISFEFFPPKNLKMHRSLWNTLNKLKIFYPDFVSITYGAGGSTRKRTHETIKKFT
YRPSIKPIPHLTCIGDTRNSIKKLAINYWEMGIKSIVVIRGDPENIKLSKKRKFVTFPNG
YNYSSELIKDLKKIRDFEIIVAAFPEKHPESINVDEDIDNLKRKIDLGASKAITQFFFDN
KKFYEFINLIEKKNIKIPIIPGILPIINFDKLNKLAESCNAYIPKKITNLYTGKKEFEFD
LSVDVATRQCIDLINNGFKNLHFYTLNRAELTGKICSNLTKKGLANKPYDAFWS
>A0A4U0ZLK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus sp. IMCC35007|TrEMBL
MEIKTASKLEKVLKNGHMAVSSECGPPRSSDARGIIDKGHLLKNHVDCINITDNQTSVTR
LCSLAACIHLKNEGLEPVLQMVVRDRNRIALQSDILGAASFGINNMLCLSGDHQSFGDHP
SSQNVFDLDSMQLIQTARYMRDEGKFLGGDDIKKPPNMFIGAAANPFADPFKIRVPRLAK
KIAAGAEFIQTQCVYNLEKFEKWMEGVVERGLHEQVFIMAGITPMRSVGMAKYMARAVPG
MDVPKELIDRLSGVPKDKQAEEGITIAVEAIERLKQVKGVAGFHIMAIEWEEKVPEIVER
AGLYPRPVVE
>A0A2E5R719|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacteraceae bacterium|TrEMBL
MVIWFFSINILSFFYEKKFKIMNENIANIKDLLQDYTIETTPKVYKKIEELKSLLPKKTW
VYITYLPDEDPRNIIETAKKIKEEGLEPIPHLPARTIENFHNLEKYIGSLSEISGVNKIL
IIGGSSSQKGNISSSIEVLRTGLTEKFQFTDIGLAGHPEGSPDINNDELDKAIIDKNNFS
KNTNANLFLVTQFFFEASSFITWEKHLNKLGNQLEIHAGLPGPANLKTLITFAKSCGIGN
SLKFLSKQALNISKIASTNTPDKIINDLSNYKKSNNYSKLSKIHFYPFGGMKRTSSWVNA
LINNDISINNDGEIKIDSFNF
>A0A1R0YZM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus odorifer|TrEMBL
MTPPKASHAPEKISEIARKQVERLKNLDLDALILYDVQEEVDRVDHERPYPYLPTIDPAV
YGDKYLRQVEVPKIIYRCVGNDTRAQFEDWVKTDENEDRFSVYVGASSSKQEVKLNLPDA
YELSKQLNSNLTFGGVVIPERHIKKNDEHIRVVEKTNNGCNFFITQATYNVEASKNLLSD
LYYYYTNNGFEMVPILFNLAPCGTAKTLQFMKWLGISIPGWLENELKYSNDILDKSIQLS
QKIFEELLDFGLEKGIPIGCSIESVSTSKLEIEASVQLVKDVKAILDKKLLSHEPNITQT
VM
>A0A3M1TH54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MDENRLLRLLGEGVAVCDGAMGTMLYERGVFVNRSFDELNLTQPDLVREVHAEYVAAGAD
VIETNTFSANRFKLAPHGLVDRLEAINREGLRIAREAAGNRARVAASIGPLGVRIEPWGP
VSLAEARAAFQEQLEALDAAGGVDLVLLETFYHLPELEQAVRAARDVFPQTPLVAMVSVT
QEGATPEGIPPESFGPTLADWGVDGVGVNCGAGPVATLEAIEGLAEAVELPLVAQPNAGQ
PRNIDGRNLYLSSPDYVASYARRFVKAGARLVGGCCGTTPEHIRAIRAAVAATRPAARPR
PSARHPRPTVPPKPVPRREKSALAASLADGRFPVCVRVHAPRGCDPEPTLETVRSLAAGG
AEEIIVPEVLGSGRMTPFALAQFVQERVGCEAAVEYSCRFRTLIRMQSELLGAYALGLKN
VILVTGAAPSLGEAPDATANLEVDSIGLTNMVRRLNEGLDIGGRSLGRPTGFHIGVHLDP
FAIDRAHEVRRFEWKVDAGAEFAVTPPVLDPEGLADFLGAVEHCRIPLLASVPLLASLRD
AERLQRETGVGHLPSPLLERLRTADAKGNVAAAGFEIAREIADALRGLVEGVAIVTPEGE
HARAARLAEALRETAHS
>A0A8I2D3L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MPGDFLAALGERVLVCDGGMGTSLYARGVQINACFDELNLSQPHLVREVHRGFLSAGADV
LETNTYLCNRHKLGPHGLDGRVREIILAGVRLAREEARGSAWVAGALGPLGVALEPYGRL
SAAAARAAFRESIDALIEGGVDLLILETFGCVEELLVAVAAARDAREAARRSLPIVAQLA
CGQDGMTLGETPVGCAAAMLADAGADVVGANCGVGPRLMLRYVQEMAAAVRAPLSAQPNA
GLPEEVDGRLMYVSTPEYFATYAKRLIRSGVRLLGGCCGTGPEHIKMLARTVRALSPGRV
AVAAAAAPPAPPQIRPLPAAEKSSLAAKLARGEFVTSVELLPPRGSNPEKARAAAALLRS
AGVDAVNIPDGPRASARMSPMCLASILQREAGIETVLHYTCRDRNLLGMQSDLLGAQALG
LRNILAVTGDPPKLGNYPDATAVYDVDSIGLVRLIANLNRGLDVAGNPLGEPGALHIGVG
ANPGALNLEEEVRRFKRKVDEGAEFCLTQPVFDRSVLERFLEKTAPHRIAVLIGILPIAS
ARVAEFLHNEVPGMQLPDRIRAAMHAAEARGGAAEAGIEIAREALLQMRDLAQGAYVMSP
AGGAKTSLAVLRVLPGFESPSA
>A0A7C2WYS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MKLTDIWKTSQVPTVSFELFPARSEKAAEKLEKTIDELVALKPDFVSVTFGAGGSTREGS
RQLIEKLKDGEGLEVIGYFAGYGLGPEDILAVLDSYQAIGVENILVVRGDPPHEGGFTPH
PESLPYASDLMAFVRPRYDFCLGVAGYPEGHIDAPSKEKDIEYLKLKVDLGAEYIITNYC
YDNQFFFDFLERCQAAGIDVPVLPGVMPIYSVKMMETLASLCGATITDEIRQGIDALPEG
DKEALLSFGIEFAVQQCGELIEAGVPGLHLYTMDRSESSVAIVNRLRSEGLL
>A0A7C3CKY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MGCAGACFVTDNFAGYQSPGRFEYVLRSGEFAVSAELNPPDSADPAEVYRAATVLTDVVD
AINATDGSGANCHISSMAICALLTRLDYAVVMQISGRDRNRIAIQGDILGGAAMGVMNML
CLTGDDVTAGDQPEAKRV
>A0A7C4MU04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MASGSGSSASFRQSLLGKRFIYGAEVVTSRGYPSDQPPSHLAMAKQLLADPRIGWISITD
SPGGAPMLPPDWLASQLPGDRERIVIHLTCKDLNRNGLESAAWRLAADGCRNVLALTGDY
PTTGFGGRAEGVFDIDSVGLIALLRSMNDGMTVAGRGGRPETLPRTDFFIGCAVSPFKRR
ESELMPQYFKLLRKIAAGARWVIPQLGYDMRKFNEVRLLLAARGLDVPVIGNVYLLNRAV
ARLFNSGKLAGCVVSDELLSLCEKYAAGADKGKQFFLELAAKQLAVFKGLGFAAGYLGGI
AKAEVFGQVIDMAEAFGPNDWHDFLKEIRFSQPDEFFLFDHDPATGLADSSRFNPDYLAS
IRRPQGRRPIGYRVSRWFHRWMFTRDRGLWRWLQRFYAKRDGKGSLLAGVARAVERGSKH
LLYGCEDCGDCSLPDCAYLCPRYSCSKCGRNGPCGGSLDARCELGDKQCFWTRVYERLKS
YGETEQMLDGPITFYNAELKHTSAWANTFLGRDHHGREPPAAADASKADSSAPRPAGPLG
KKPAQDLAEGENAANDKSDNAPKDDAGQL
>A0A7V2UXU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSNRTTLLDRIRQSPLVFDGAMGTMIYDKGVFFNACYDELCRSRPDLIRGIHADYIAAGA
EVIETNTFGANRLKLREHGLGDQVVAINTAGVRLARDVAGNEAYVAASVGPCLTGAQAWQ
ESHAAEIRDALAEQIGALASAGVDLFAVETFVHPQELALAASVAHATGIPVLASLVLRSG
EETALGGRVEEVVAALDRNPDVDLIGLNCGVGPSDAYEAAERILPLISKPLVVMPNGGLP
RLFDGRMFYLTSPEYFTEYAKKLIELGVRGVGGCCGTTPEHIRVAAKAVKSLSSVKRHVS
IRTYRPEDVEVQVTPTAKKSRLARRLAEGARVSSVELLPPKSCDMSGLIERARRCREHGI
DAINIPDGPRASARVSPLIAAMVLLREVGIEPILHYCCRDRNLIGMQSDLLGAHVAGVHN
LLIITGDPPKLGDYPDATGVFDVDAIGLMKVVTGLNHGRDVGGSPVNPPTALFAGVGANP
CAVAPDTERIRFRLKREAGAEFAITQPVFDPDALMRFLDAVEADGSRIPVIAGVWPLVSL
KNAEFMRNEVPGMTVPDAVMDRLRRCNTKEDGLRTGVEIAREICSRIADRVSGFQVSAPF
GRVDIALQVLDGFTSPERPSSS
>A0A7V2LBI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MKITEIWKTSGKPTVSFELFPARSDKAAERLDKTIDELTTLKPDFVSVTFGAGGSTREGS
RQLIEKLKNEKGLEVIGYFAGYGLGPGDIHAVLDSYHVVGVENLLVVRGDPPQEGDFTPH
PESLPYASDLMAFIRPKYDFCLGVAGYPEGHIDAPSLAKDIEYLKLKVDRGAEYIITNYC
YDNQFFFDFLERCTAAGINVPILPGVMPIYSVKMMETLADLCGATITDELRQGIGDLPEE
DKEALLTFGIEFAIRQCRELIEAGVPGLHIYTMDRSKSAVGIVDRLHSDGLL
>A0A8F1WIP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirales bacterium LBB_01|TrEMBL
MSFKDTLESGKFVVTAEVGPPKGTDIATMKHDMEILKGKLDAVNVTDNQSAVMRICSLAV
CKLALEHGLEPILQMTCRDRNRIALQSDLLGASVLGIRNVLCMTGDHVSAGDHKSARPVY
DIESVQLLQVVNALNNGKDMAGNDMKGATSFFQGAVVTPESNPIEPQLMKFEKKVKAGAN
FFQTQAIYNIDNFKEFMKFARKFPVKIMAGLVVLKSAGMANFLNNFVPGIKVPQELIDEM
KAAGKEKALDTGLNITARHIRQLKEEKICDGVHIMAIGMEDKVPIILERAGLL
>A0A7C7YQM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MMEWNPEGSTILEIVPPTLKSGLEGLHKRLAKVRRLIEGGDFDAINIPEIHEEESRNDRG
SRIRECSPRMQPRELGRRIQDELGLPVIVNHVVAFEPIEQLLEWAQETIHGHGISNLILV
GAPHDRRSWPGPPVAVANQALQKQFAGADLQIGNICIPERADSPISEAVRMEEKARMGAN
FFSTQIIFEAREISSLQIDLDREAPCAREAPLLVSLCPVKKIRQLDFLRFLGVRVPDSLE
ALLSTVPEAQCLDLSLEILGDIQTRLIDQQPKNCPPLGWNIAPVGPIPVPDIEALMQLLP
GSVQS
>A0A7Y4TRZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MRVIDHIKQAKDTLISFEILPPLKGKGINAIYNHLDPLMEFKPAYINVTYHRSEHIFKKK
PDNSFEKVVIRKRPGTEAICASIMNKYNVDTVPHLICGGFSVQDTEDALLTLSYLGIDNV
LVLRGDAAKNETSFIPEPGGHKYALDLLKQVIDLNNGVYLEEELKGTSSTTFCTGVAGYP
EKHFEAPNMQTDLINLKKKVDAGADYIVTQMFFDNKKFFAFEKACREAGITVPVIPGLKP
ITSTKQLTIIPRTFYVDIPTDLSAEILKCKKDEDVEKVGTEWLLTQSKELKKAGVPVLHY
YTLGKPHVVANVVREL
>A0A7V9M1T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTDHIIEAKGTVISFEILPPLKGKTINSIYDHLDPLMEFNPAFINVTYHRSEQVFKKK
ADGTFDKVEVRKRPGTVGICAAIMNHYKVDAVPHLICGGFSKQETENALIDLAFLGIDNV
LVLRGDAAKNETLFEPEINGHRYAIDLLKQVVDLNSGIYLEEDIRDGYKTKFCIGVAGYP
EKHFESPNMQTDIEYLKTKVDAGADYVTTQMFFDNKKYFEFVKKCKESGIEVPIIPGLKP
VTSKKQLSVLPRTFYVDIPTELSSEILKCKTDADVEIVGMEWLLQQSKELQEAGVAVLHY
YTLGKTHVIANVVRNLV
>A0A7J8ULX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium klotzschianum|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DALVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A4Y5SJ17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermococcus indicus|TrEMBL
MVGLRLSSCPKGMLNGPCGGALGERCEVDGRMCPLLRRLEVEEAPFEEHPVLREMEKLVE
GDTRPRDSAFWRGLELGRALTLEFPISAVRTWEDVHLVVGSVRDVDLLTVPDNPLGYPHF
EPTAMALYLKSLGRPVCPHLTGKDRNLTAVASELRTALLFGFEAVLMTTGDWPGLSLPSR
PVFDLDSANLIRLARLVFAGILPTGERFEADERPRVLGTINPHYRPALEAKRVLRKLVAG
AEALVTQVVASKESLSRLKEVLRSAGGDVPVLVSLLHPLTEELRPALERMGIPAGDEGFE
ELLEEVKTLDFVSGINLIVFSRSLEGWLSLATDAVKTTKEVFE
>A0A4R4LPG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura sp. KC216|TrEMBL
MPRLRLDRPPTVRELLASGAKSFSFEFMPPKTDKGARNLWRVIRELEPLHPTFVSVTYGA
GGGTRDKTVESVERIATDTTLTPVAHFTAVNHSQAELRQLIGRFAAAGVRNILAVRGDPP
GDPMGEWVKHPEGVEYAAELVRMIRSYGDFSVGVAAFPYKHPRSPDIESDTRYFVEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDIPIIPGIMPVTQLSTIERSEQLSGAPFPPEV
KARFDAVADDPDAVRRLGIEHAAELCQELLDQDAPGIHFITFNKSTATREVYGLLDAAWY
GASGRVPPMTA
>A0A800E3L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MRIVDLFGAGAPVISFEFFPPKTDEGIETLYRTVKELRPCRPSFVSVTYGAGGSTRDRTL
ELVARIQRDLGITTMAHLTCVGSTKDEIRETLERLYASGIRNVLALRGDPPKGETEFQAT
EGGFRYGTELVSFIRELGMDWCIGAACYPEGHVESSDLEDDLAHLVEKVDAGADFLVSQL
FFDNDDYHAFVRRAGSAGITVPIVPVLMPVTNASQAERFTKMCGARIPQELNRRLRIVEN
DSAAVVATGVQWAVDQGRELLKRGAPGLHFYTLNRSSATLAVHAALGL
>A0A8H5EKY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIISELIDRIKAIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A660VCL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSRLKEVLEAGVFAVTGEIGPPKGVTVGTALEEAEEMASHVVAINVTDLQSAVMRVSSLA
MCKLLLERGIEPVLQLTCRDRNRLALQAELLGAAVFGIKNALLLTGDHMVLGDHPEARPV
FDLDSVQLLKAASELKAGRDLSGHELDGTPDLFIGAVATPEFEPLELHLIKMRKKVEAGA
QFFQTQAVYDGDRFKQFADAVSGWGVPILAGIVLLKSAGMARYMNQNVAGVSVPQELIDE
MAATPKEKRREKSAEIALRIVEQIRPYCAGVHIMPLGWADVAAEVAKQINQKTRQEVESR
IQKLQSELDDLKARIPAHSASPDMLLQQEKLEKQIERLRALMPK
>A0A3S4GBJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. arizonae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATGDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDIYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2C6BZZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. polymorphum|TrEMBL
MKIADIYKSKNLTTSFEVFPPNDKVGLEEVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHFTCIGSKKEEIDRVLEDLERNNIENILALRGDYPVDRELEPGD
FNYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVDAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A246EG50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. polymorphum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEIGD
FNYAKDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A5C8BT72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquabacterium sp|TrEMBL
MTKSSPNSLPVSVEFFPPKTPEGVEKLAAVRQQLYAIRPEYCSVTYGAGGSTQDGTIQTV
RAILSEGCDAAPHFSCIGASKASVREQLAQFKADGIKRIVALRGDLPSGYGGFGEFKYAS
DLVAFIREETGSHFQIEVGAYPEMHPQARNPQADLQAYATKVKAGANSAITQYFFNSDAY
FRFVEEAEALGATIPVVPGIMPITNSSQLLRFSDACGAEVPRWIRTRLEGFGDDKASIQS
FGLDVVTDLCEQLRAGGVPGLHFYTMNQSAPVLALCERLGLIPA
>A0A0F4YNC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rasamsonia emersonii CBS 393.64|TrEMBL
MEKIIDKIAALPPDAHYFSLEFFPPKTQMGSVNLQARLERMARALRPLFVTVTWGAGGTT
ATKSLELAEICQRQLQLTTCLHLTCTNMNRKLVDEALEEAKVLGIRNILALRGDPPRSEE
YNIDGDDENDSNKEFTYAVDLVRYIRRVHGDYFCIGVAAYPEGHPGDSYTEPQDPVKDLP
YLVEKVKAGADFIMTQLTYDLEAYRKFEEMLRNHESGVFKTIPIIPGLMPIQSYNILTRV
TKLSHANIPPHILSRVEEVKSDDEKVKQVGVDILSEIVDGIKDIPCPGPRGFHFYTLNLE
KSVSFVLERCDLIPPMTEDNDELDRDRDIAVIAAAQNGVLDENQKRSRRRASSINSQPYN
RVIVDKLRVPSEKSSGGSFSYETTALSAGVPAMNPPPRSTTLQISEGVGSLGREATWDDF
PNGRWGDARSPAFGEIDGYGPSLHVSATVARRLWGYPTSRSDINTLFRRHVSGELHIVPW
SEGGAPEETGGLNAETATIRTELLKLIDKGWWTLASQPAVNGVRSDHPIFGWGPPGEGFV
FQKAFVEFFCPGEDYQSYIKPLLQRYGEDEFAWFATNAAGDFESSFSLATGTTTTTTGAG
TGSAADEFSELHDNSRGMAVTWGVFRGKEITTPTIIEEVSFRAWGDEAYRIWDEWRRIYP
RGSPTERFLDATKKDVWLVCVIGQRYGAGTEPGSAEEDREAKMLWRVLAGEEQEPDYDPI
DHDDTGTLKKIERGMEWNLYYPEMKYYVCSESGPLTSLLNDFMN
>A0A3M1ZW80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium|TrEMBL
MRVSKILQQRHGPLVSCEFFPPKTDRGEDNLWLCLRDLEAIRPDFVSVTYGAGGTTQDRT
KRIVKRIHQETALVPVAHLTCVGATAEDIRALLSEYEEADIENILALRGDPPEGTDRFET
TTGGFAHASDLIRFIRSINHFSIGCATYPEGHPESPAGVQDDLRYLKVKQDEGAEYAITQ
YFFDNDHYFRFVDAAQNMGITIPIIPGIMPITNFDQIERFSRMCGASIPAWLHERMDPIR
NDLDRVF
>A0A2E5WQW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDILREHHAAGRTPVSCEFFPAKTPAGETALKETIAPRLKAIDPAFFSVTYGAGGS
TRDQTLDIVQTLQQQHGVPTMAHLTCVGSTAADISGFLDXARARDIQNILALRGDPPAGQ
EAFVXPEGGFEFSYELVXXVHARGEFSIGVAGFPEGHIACTEGREXDWQRLXAKVDCGAD
FVITQLFFDNADFYAFRDHLRGQGMTQPILAGIIPILSARQIQRFSELCGSKLTPEITDR
LDALGDDDEAVAAFGIEYATRQCADLIDNGVDGLHFYTLNKSRATLAVAGNLDLAR
>A0A366ZXG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. TF02A-26|TrEMBL
MVFGPCGGVRADERCEVAEHRCVFVGEPLVTWPAEPLPAPPPHPGSLLDVARSRPVVLTD
LSVVPYDPASLRRVVEVIGPVSDGLLVGEHANRPDFPPAVVAAEVHAAGGRLWTTLACRD
RNRVVLEQEVAGLAALGVDGVLCVTGDARGPGVRPGATQVFDLDGPRLVALATGAGLSVA
VPESPAAPPVDLRPARVAQKQRAGAQVCVLNHVRTPAEVARFVAAARAAGATVPFVAAVA
VYTDERSARVLQRFPGLQVDDDAIEAVLAAPDPREAGIAAAVAEAAALLAIDGVAGVNLS
GLASADGEDEGARVKAEVAGRIREEHGG
>A0A0Q7V006|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. Root1472|TrEMBL
MTVPPLRRVLGPVARAGERTDRPRVSFEFFPPKTEQMEENLWAAIKRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILDETNLKPAAHLTCVGASRAEVDEVIREYWETGVRHVVSLRGD
PPPGEGGIGGVYVPREDGYRNATELTSALRAVAPFNVLVGVYPEKHPESPSIEHDIEVLK
AKVDAGATLAISQFFFDTDAFLRFVDKVRAAGITIPIVPGIMPVTNFKGLVKMSAACQTA
VPAWLANLFDGLDEDADTRRLIACSVASEMCAKLQEQGFSDFHFYTLNRADLVYAICRVL
GVREIAPAPSPVSAEAAA
>A0A6G6FGD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudohalocynthiibacter aestuariivivens|TrEMBL
MTTPSVSFEFFPPKSLEASFRLWDTVHTLAPLAPRFVSVTYGAGGTTRALTREAVGTLHQ
ATGLNVAAHLTCVDATRAETMAIADEFAAAGVQEIVALRGDPPKGATGFTAHPDGFTDSC
ALIEALADRGDFKIRVGAYPEPHPEAAGDQADVDWLKRKFDAGADEAITQFFFDADTFLR
FRDRCAKAGIDKPILPGILPIENWKSTRRFAAACGAGIPDWLDSAFTTAERDDRCELLAT
AVATELCSKLIDEGVENLHFYTLNRPELTRDICHALGVTPRVELRDVA
>H1PQ34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium ulcerans 12-1B|TrEMBL
MKISELFKNKKTVVSFEVFPPNTIYSLEDVYSSIDELAKLQPDFMSVTYGAGGATRGRTV
EIASKIKNDNKIEALAHLTCLGAKANEIDDILEQLRKNNIENILALRGDKPKDGLPVEEG
DFKYAQDLISYVKGRKDFSIGGAYYPEGHQETNDLLDLFNLKTKVDSGTDFLISQIFFDN
ESFYRFRDKVDKLQINVPLVAGIMPVANAKQIRKITSMCGCSIPEKFQKILNRYEDNPKA
LKEAGTAYATEQIIDLITSDIDGIHLYTMNKVDTAKKIMANIAHIREISGGSR
>A0A7L6DY76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. RHBSTW-00903|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIARDYWQNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A524DL83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAEKKVYSKLGEALAKGEFVLTGELEPEKTCDLSHLVHEAKEMAPYVVAANVTDSPLGIV
TINSLAASYIVQRDSGLECIWQMTVRDVNKLGIAGMIMGAQALGIHNILSLTGDHPNMGD
MPESKPVFDLDSATLVKLVREMVDTGAINGKEIESPPKLHVGAAANPNADPMEAEILKIG
RKAEAGAEFIQTQVVYDLDRT
>A0A524EZV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAEKKVYSKLGELLAKGEFILTGELEPEKTCDLSHTIQEAKEMAPYVVAANVTDSPLGIV
TINSMAASHIIQKETGLECIWQLTVRDVNKLGIAGMIMGAHALGIRNILSLTGDHPNLGD
MPETKPVFDLDSATLVKLVREMVDTGKINGHEIEHPPTMHVGAAANPNANPMEAEVLKIG
RKAEAGAEFIQTQVVYDLDMTIEFLRAIQKYKVPVFLGIFPMKSYGIAKGFDMFVPGVDV
PKDILAKWKSVKTDVSDKKEQKDVYDRLNYEFFKPFISELKKKGLLAGIHCMAVHYTRIF
PKLVEVVKA
>A0A524FB10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MANRTAYSNLVKTMREGKFLFTGELEPKKMFDLSSVLHSAEEMKKTGKIVAANVTDGPQG
DAYTCSMVPSYLVQEKVGLEAIWQMTVRDRNRIALFGDILGGSILGLKNLLALTGDHSAL
GDNKNARAVYDLDSTQLIDLVSKMVDDGTDLEGNEIEGGKVEMNVGCAANPNSDPREPEI
LKVGRKVEVGADFIQTQTSFDIDEAKEFLKDLEKFNIPVLLGLFPIKNYGIAWYFNEYIP
GVSVPKDFLNDLKATKKIKDKKEKYAKIDQINIDFYVPFIKEIKKTTKAAGVHCMAVHYE
RLFEPLLKEF
>A0A5C9EZ85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAYSKLGEMLEKGEFVLTGELEPEKTCDLSHTIHEAKEMAPYVVGANVTDSPLGIVTINS
MAASHIVQREAGLEVIWQLTVRDVNKLGIAGMIMGAHALGIRNVLSLTGDHPALGDVTEA
KPVFDLDSATLCSLVREMVDKKSINGHEIECPPTLHVGAAANPNADPMGAEILKIGRKAE
AGAEFLQTQVVYDLERTIEFLTEIRKYKVPILLGIFPMKSYGIAKGFDEFVPGVSVPKDI
LAQWKSIKKEITDKKDQKEAYDNANYEFFKPFITELRKKGLLDGIHCMAVHYPRIFPKLK
SVIEDSN
>A0A842WYM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MKEHKKLSRLCQLLEDETFVVTGEITPPHGADSSLVNHRASIIRDYCDAINITDNVRGIP
SMSSMVCGHLLLKAGIEPIMQMSARDRNRVLFQSELYGAYALGIENVLFITGDHTLLGSH
PQTKMVYDIDSIQALELARHLMSGMDLAGADLEGTPSFFLGSTFNPYADPMPLQAMRVFK
KQDAGAKFFQTQAIYDVSRFEEFMGHIRSVEAKVIAGIIPLKGPRMARFMNKRIPGFKIS
DEIIHRLESAGAGLSGKDKRDAIRAEGLNIAIETVQRVRTISGVDGIHIMAVGWEESLPE
IVKRSNLYPRPQ
>A0A0M0K4I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chrysochromulina tobinii|TrEMBL
MQNCSSREPDEAAFNKWLDDATMRNHHTLNLVGPSSSREGPRLSMERAAALVKARKNLAF
GCVTIAERHLTKGTEHLNILRKVDFGAQWFISQAVYDAEATIKLLHDYADECRRRGQKPV
KILLTFAPVGRPKTLEFARWLGIHMPEAVEQRILAKANASESKSKEAAVLESIDVCCEAL
ERILGAAGQCGVPLGLSVESISGFREEIDGCFEMFRRLQAIMLDSKGSPWAVRWYRVPVQ
SMARSNSGEQLAALEAKLEALEEAKGGQLAGGQQPTAKEELAVKTKEAQIAMRDSLLGFA
AGIAVGAVAAVAISRKLVR
>A0A5Y2LWX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTYIDATRNELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A370GPG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquicella lusitana|TrEMBL
MNVISSQNISFEFFPPKTDEGESQLQDTAIRLAEYHPHFFSMTFGAGGSTRAGTIEMVKM
LQGKTSVPVAPHLACIGSSREEMVGVIRQYQDLKVRRIVALRGDLPSGMVQPGEFRYASE
LVALIRETAGDFFHIEVAAYPEIHPQAKSVEDDILNLKRKYEAGASSAITQYFFNPDAYF
YYLDECAKHSIYMPIVPGIMPITQFSRLVRFSEMCGAEIPCWIRKRLESYGDDMESIKAF
GFEVVFHLCQTLIAGGAPGLHFYTLNKSEATLKILENLNISIHRPNLPRYVASQKIG
>A0A0B4HQR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium majus (strain ARSEF 297)|TrEMBL
MDKITDKIAALPADREYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSKRLVDKALEDAKALGIRNILALRGDPPRKEE
YCDAEDSEDDGQQDFTWAIDLVKYIRRKHGDYFCIGVAAYPEGHSDESHPQDQSLEHDLP
YLVDKVQAGADFIMTQLFFDISAYDHFEKTLREHPSGAFKTIPILPGLMPIQSYQMIKRT
TKLSHAKMPPAIMDRLDAVRGDDEKVKLVGVDIISELIDQIRKIKSRTPGRRGFHFYTLN
LEKAVSFIVERTGLIPRESENEEALIDDGTLAPPAIQVNGTRASTHSRTSRRHSSVGSDP
YNRVIVAGQPPSHPEWEATGQEAGVPAESINSRANTLAISEGEGVLGREATWDDFPNGRF
GDSRSPAYGEIDGYGVSLHMSVNQAVTLWGSPTSRQDVNNVFVRHIKGEISAIPWSEEGL
SPESSTIQSRLVEMNGKGWLTVASQPAVNGISSSDRTFGWGPVNGFVFQKAFAEFFLPSA
DWHTLAEKLKGSDYFDSVCFYAANAKGDFVSSDTSGGRSTRTVAASTNAVTWGVFPGKEI
VTPTIIEEVSFKAWSEEAFGLWGEWAKVYGRGSESEKVLSGIRSDYWLVNIIHHDFIDRE
ALWKLLLE
>A0A4Q3PVS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MTNLSNETGVRHRSSNAADLVRNMSYEVMPFKNTEQDVVDHVPKTVPLTVTVTEAKGIDT
TLNLTERLINHGYQVSPHLPGRQFVDDAHVADVIARLSEIGVKSVFVIGGDAPNPAGKFV
DAFGLLRAMEEVGHPFQEVGIGGYPEGHGAIEQELIDLALQQKAPLATRILTQICFDATT
TSKWAAGVAASGVDRPIYIGMPGPVSRQKLMRISAGIGLGQSARFLQKQQSMLWRFLLPG
GYNPTRLLKQLGGAVPKTSNNIAGLHIFTFNELRKTEIWRQKLLTAIVEKDARS
>A0A415W3G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM18-55|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPDLCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A2S9QP62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter massiliensis|TrEMBL
MTGKDIPSLEEARDAIPPGTRVNITFLGNEDLPMRTAAAAAVAASGFTPIPHVSARRLAS
EAQLEEFLGELQRVGASERIFAVGGDPATPEGPYDSALDVIRSGVLQRYGVREVSISGYP
EGHPDIPEEVLWEHLELKAAALRDAGLGAVILTQFAFDTEPVMAWVRGVRERGIDVPIRI
GTPGPAGIKRLLSFARRFGVGANATIVKKYGFSLTNLLGTAGPDTFVDDLAALLDREPSA
GEVKLHMYAFGGLRATAEWARDYQRRAGS
>A0A4V0X8G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MKLISETPLSMEFFPPKTQEGEAKLRLVRQQLYALRPQFCSVTYGAGGSTQAGTFNCVRE
ILAEGVSAASHFSCVGATRESVSEQLAVLQAMGVRRLVALRGDLPSGYGAHGAFRHASDL
VAFVRAQTGRHFHIEVAAYPEVHPQAASPAADLQSLLAKEQAGANAAITQYFYNPDAYFR
LVDEAQALGLRLPIVPGILPIINSAQLMRFSDGCGAEIPRWIRLRLNSLGDDGSAIRAFG
LDVVTALCQRLLAGGAPGLHFYTMNQSAATLEICRRLALS
>A0A4Q5VTQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRSQLYAQGPEFCSVTYGAGGSTHAGTFQAVREILEE
GVPAASHFSCIGATRATVRSQLAELKAMGVRRLVALRGDLPSGYGAGGEFQYASDLVAFI
RSETGHDFHIEVACYPEVHPQARSPEADLRAYAAKVHAGADSAITQYFYSPEAYFRFVDD
TVKLGLSIPVVPGVMPITSSAQLLRFSDACGAEIPRWIRLRLLSFGDDTASIKDFGLDVV
AALCERLRDGGAPGLHFYTMNQSASSLALLERLGWRA
>A0A1H5V600|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium lactis|TrEMBL
MKIVDHIKNAKGKTLYSFELLPPAKGQGIQSIFQTMDELMEFKPPFIDVTYHREDYLYKQ
HSNGLLERVSYRKRPGTVAICAAIMSKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTVGGHAYATDLLQQVVDMNRGQYLHEDIVTSEKTNFCIGVAGY
PEKHFESPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVTKCRENDIHVPIIPGLK
PLTTKKQLITLPRIFHLDIPEDLSDAVESCKTNADVRQVGEEWLVQQCKELIEFGAPVLH
FYTMSNPGPTRKIVEKLV
>A0A1G8CW00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus glaciei|TrEMBL
MGLLDELKTRILTADGAMGTLLYSYGIEYCNEELNLQRPEIIEKIHQEYIQAGADIIQTN
TYGGNALKLARYGLENQVKEINEAAIRIAKRAAAPGGQFVFGTIGGIRGIRKSDATLEEI
ITMVDQQAGYLLVGDPDALLLETYYDFEELAATVTHLRKATDVPLIAQVSMHEPGILQNG
MALNDALHQLEALGADIVGVNCRLGPHHTIQALEEVALPQKAFLSAYPNASLLDLENGRV
VYESEADYFGRAGLLLREEGARLIGGCCGTTPKHIEALKKRIGHLKPVTEKEVVKKKPII
IREAEALEEAPLHEKAKTERTIIVELDTPRHLDITKFLEGSKALSAAGVDAVTMADNSLA
SPRVSNLAMGSILKHQEQIRPLAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIESGADYFISQPVYTKEKIIEIYEATKHLETPIFLGVMPLTSIRSAEFLHNEVPGI
KLSEDALERMRACGDDKERATAEGIQIAKELIDTAAELFNGIYVITPFFRYDMSLELIDY
IRQLDIQKESDNSHVKTAN
>A7MXA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio campbellii (strain ATCC BAA-1116 / BB120)|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDATRDELIDIADDYWNNGIKNIVTLRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A7H8QA55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus glaciei|TrEMBL
MGLLDELKTRILTADGAMGTLLYSYGIEYCNEELNLQRPEIIEKIHQEYIQAGADIIQTN
TYGGNALKLARYGLENQVKEINEAAIRIAKRAAAPGGQFVFGTIGGIRGIRKSDATLEEI
ITMVDQQAGYLLAGDPDALLLETYYDFEELAATVTHLRKATNVPLIAQVSMHEPGILQNG
MALNEALHQLEALGADIVGVNCRLGPHHTIQALEEVALPQKAFLSAYPNASLLDLENGRV
VYESEADYFGRAGLLLREEGARLIGGCCGTTPKHIEALKKRIGHLKPVTEKEVVKKKPII
IREAEALEEAPLHEKAKTERTIIVELDTPRHLDITKFLEGSKALSAAGVDAVTMADNSLA
SPRVSNLAMGSILKHQEQIRPLAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIESGADYFISQPVYTKDKIIEIYEATKHLETPIFLGVMPLTSIRSAEFLHNEVPGI
KLSEDALERMRACGDDKERATAEGIQIAKELIDAAAELFNGIYVITPFFRYDMSLELIDY
IRQLDIQKESDNSHVKTAN
>A0A7V1BZT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MHVAEILARETGPFISVEIIPPRRGGRIQQVYDAIESLLPYRPRYINITSHAAEVIWQEQ
PDGTFRRRVKRRSPGTFGLCAVIKYKYDIEPVPHLLCHGFTREETEDALIELHYLGVENV
LALQGEEKYARPPRPDRTVNQYAVELVEQIIALNHGRYLDELTDAQPTNFCVGVAAYPEK
HYQAPNLAFDLANLKRKQDAGASYAITQMFFDNQLYYAFVEKARALGIHIPLIPGLKILT
RREHLHSLPRSFHVSLPEELTTAILEAKDDREVAEIGIEWAYRQAIDLLSHGVQNLHFYT
MLYTKPLIRLMEKLKLD
>A0A7V5DCK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHFKKAKGKTLVSFEVLPPLKGGSMQSIFKTLDTLMEFKPPFIDVTYHREEFLYKQ
RPSGYYEKTAIRKRPGTVGICAAIVHRYGVDAVPHLICGGFSAEETENALIDLNFLGINN
VLALRGDARQFEDKFIPNENGHKFALDLVRQIVGMNEGRYLDSNIVNGERTDFCIGVAGY
PEKHFEAPNLPTDLHFTKQKVDAGASYIVTQMFYDNKKYFEYVDDCRKAGIEVPIVPGLK
PLTKRYQLNSIPRKFYINMPEEFVSEVLKAKDDEAVQQIGIEWCIQQSRELKAAGVPCLH
YYTMGDTETIKTIAGSVA
>A0A7V4GYN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEVLSRSKETRFSFELLPPLKGSSIQVIYDAIDPLMEFNPLNINITYHQSEVEYRRL
PGG
>A0A2T7U4X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga sp. KLBC 81|TrEMBL
MSPMALRPSRQASSPINVSFEFFPPKTPEMETTLWASIQRLAPLNPQFVSVTYGAGGSTR
ERTHATVSRIVKETHLKPAAHLTCVAATKDEVDDVVRSYWDAGVRHIVALRGDPVSGIGT
AYEPHPGGYQQTCDLVAGIKAIGDFEVSVSAYPEKHPEAASLDADIDVLKAKVDCGADRA
ITQFFFDNDHYFRYLDRVRARGIGIPVVPGIVPVQNFKQTANFAAKTGASVPDWLAARFE
GLDNDVETRKLVAAAVAAEQVIDLVDRGVNEFHFYTMNRADLVYAICHLLGLRDQSVKVA
A
>A0A317IZV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHLKTAKDTLISFEILPPLKGKTINSIYDHLDPLMEFKPSFINVTYHRAEHTFKKK
SDGTFDKVEVRKRPGTVGICAAIMNHYKIDAVPHLICGGFTKRETEDALIDLHFLGIDNV
LVLRGDAAKNETYFEPEPDGNRYAIDLLKQVGHLNNGIYIEDDIRNGFRTDFCMGVAGYP
EKHFEAPNLATDLRYLKAKVEAGAEYVVTQMFFDNKKFFDYVKACRDAGIDVPIIPGLKP
ISSKKQLSVIPRTFYVDIPTDLSNEIMKCKTDEDVELVGVEWLTQQSRELKKSGVPVLHY
YTLGKSKMIRDVVKAII
>A0A1H9W547|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentzea albida|TrEMBL
MTSVVERLQGESPKFSVEFLPPRDAEDEKVLWKAVRELEGLDPAFVSITYGAGGSRRDRT
IRATGRIAQETTLLPVAHLTAVEHSVAELRNVIGWYAAIGVRNILALRGDPPGDPMGEWV
AHPEGLSYADELVALVRELGDFCVGVAAFPYGHPRSTDLDTDLKYLLRKLNAGADYAVAQ
LFHAPEPFLRMRDRVAAAGCSAAILPGIMPMLSPRGLAKIVELSGADLPLDVSRRLEPYA
DDVAGFRATGIDIATEMCQRLLDEGVPALHFYTMNRAKATREVLGRLGLVTRA
>A0A521HLN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHLKQAAGKTLFSVEILPPLKGKSIQSIYDILDPIMEFKPSFVDVTYHREEYVYKK
RENGLLEKFSMRKRPGTVGICAAIINHYKVDTVPHIICGGFSREETENALIDLNFLGIDN
ALLLRGDAIKSEAAFEPHPFGHLYALDLVSQVVNMNKGIYLDEELRDVAPSNFCIGVAGY
PEKHFEAPNLKSDLKFLKAKIDAGAEYIVTQMFFDNKKYFEFVEKCKEAGINVPIIPGLK
PLTGSKQCTSLPKIFHVDIPEDLEEAISQCKSEKDVKQVGMEWCINQSKELMKAGAPCLH
YYTMGNAENTIRIAKELF
>N1UAQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira weilii str. Ecochallenge|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPDGDLKLMETVKELALLDPDFVTVTYGAGGSTRDK
TVQILSEISKRYSFPTVSHFTCVGANQDQIFKALKEIRSSEIVNLMALRGDPPKGEGKFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPDAKSLEEDVENLKRKVDAGTDFLVS
QLFL
>A0A523GBQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKITELLAQATSLQISYEIIPPKRGGSVRDVIEIVEDLVEFDPAYIDVTSHSAQVSYEEL
PDGTWKRHVNRKRPGTLGLCAAIKSRFGIETVPHLLCKGFTREESEDALIELNYLGIQNV
MALRGDDSGFMKPIGGDRTVNKYAVDLVRQIVDMNEGRYLEDLMDASSADFCVGVAGYPE
RHFEAPNMNRDIQYLKQKVDAGAHYVTTQMYFDNTEFFKFVELCREAGITVPIIPGLKIL
TSKRQLHSLPSRFFVKIPEALETEVEDANDEHVVDIGVEWAIRQCEELLNAGINNLHFYI
LLKPNIVTRVVGHLRKMA
>A0A2T4XC28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEYFKQANQQTLISFEVLPPLKGGQMQDIFDALDPLMEFKPPFIDVTYHREEFIYKK
RASGYYEKTAIRKRPGTVGICASIMHRYGVDAVPHLICGGFTEEDTENALIDLHFLNINN
VLALRGDARQFEGKFVPEAGGHEYALDMVKQVVDMNNGKYLDTNIENGAHTDFCIGIAGY
PEKHFESPNLELDLQYTKAKIDAGANYIVTQMFFDNQKYFAYVDACRAAGINVPIVPGLK
PLTKLYQLNSIPRLFHLDMPADLVKAFSEAKTPEARLTVGIEWCVAQSKELKAAGAPCLH
YYTMGDSSTIRRIAENVY
>A0A2T4WTD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHIKKANGNTQFSFEILPPLKGQHIQSIFDNIDPLMEFNPPFIDVTYHREEYVFKE
LENGLLKKQVVKKRPGTVGICAAIQNKYSVDAIPHILCGGFTKEDTENFLIDLDFLGINN
VMALRGDAVKSETYFKPEREGHSYATELVAQIQDLNQGNYLDEELLNSSTTNFCIGVGAY
PEKHMEAPSLDSDIHFLKKKIKNGAEYIVTQMFFDNQKYFDFIKKCRKANIMVPIIPGLK
PIATKKQLNLIPHRFHVDLPEDLIIAVVKCKDNAQVKQVGIEWCIQQSKELQKAGIPVLH
YYSMGKSENIKSIASQVF
>A0A0D8J7R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Draconibacterium sediminis|TrEMBL
MKVIDTINQAKKTVFSFELLPPLKGNDVSRLHKTIESLTEFDPKYINITTHRDEIEFKEL
ADGSIVKQTVRKRPGTVAIAADIQHKYGIPVVPHILCGGFTKSETEHVLIDLNFLGINNV
LALRGDGLKNQHVFQPTENGHSNANELVKQIKDLGEGKYLDADLKNNKPLDFCIGVAGYP
EKHFEAPNMEQDMAYLKQKVDEGADYIVTQMFFDNQVYYDFVDRCRAMGITVPIIPGIKP
INLKNQLTVLPKIFSIDLPQELSKELTKCKNNDDARRVGTEWAIFQSKDLVAHNVPSLHI
YTYGISDNVSEIVKAAF
>Z9JNF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium phenoliresistens|TrEMBL
MVDAPAVDPRCSTPGAVEHRPQFEVIPLPGALEAVIAHLPPGSRVSVTSSPTQGQEASLA
LAADLARAGFTAIPHLAARRIRGAAQAQEMAARMEEAGIREAFVIAGDPALPAGGLSGSL
DLLEALHAQSPLLVAGVAGYPEGHPHAEPAAELDLLRRKAEHASYVVTQMCFAPRPIIDW
ARRAREAGVDLPVRPGVAGPVDLARLLRIGSRVGVGPSLSVLRRHGTGLRRLMRPGTWSP
EDLLADLARDARAARLELAAPHVYTFNALELTGAHWAGR
>A0A1E4CMZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. SCN 70-27|TrEMBL
MTTTLRRGVRPRPPGLHPLFPVSDMTTTTPISFEIYPPRTDAGLPALYETIRALASVDPR
FISVTFGAGGSTRSRSLGVLTHILRETSVPPLAHLTCVGSSYAEANALIREFLDAGITRF
LALRGDPPEGSSEDDVFLGDLESAAQLVQLIGRVQAERVPYAERPVPGSDAVRVASRDRV
EIAVAAFPNGHPRALRSADDIDALLAKQAAGATFAISQVFFHAHDYVSFVARARTAGVTI
PILPGIMPITSPARLRRVLELTGEPLPSQLAIDLEVEPTTEGRRDIGIAHAAELAREVVA
QGAPGVHLYAFNNHDTVLAVLREAGLITEHRPLNKETAR
>K9H2D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium digitatum (strain Pd1 / CECT 20795)|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEAAENGFCYAKDLVKYIRNKYGNHFDIGVGGYPEGADDNADVDQLIDHLKEKVDAGSSF
VVTQMFYDADNFIEWVKKCRAKGITVPIIPGIMPIQTYASFIRRSSWTKVHVPPQWMEAL
EPVKNDDSAVREIGKTLIANMCRQLIAAGIKHLHFYTMNLAQATQLVLKELDLSPSEESP
IQRALPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSVKDISDIFVDFLTGKLDRLPWSDSPITTEAHEIQEDLLK
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSSLIDELITRIEKND
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCYDAASPSRKLIQQVMDDWYLVNIVDNDFHRSNAVFELFNGLEIKGLNVEVDGKPLTNG
HAEQNGVAAN
>A0A168D7X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moelleriella libera RCEF 2490|TrEMBL
MGFSNLRHRLQRMEQALKPLFVNVTWGAGGSTATKSLELAELCQRELGLTTCLHLTCTNM
SQHLIDKALEDAKVLGIRNILALRGDPPRREEYRDTEDSQDDGSDSFTYAIDLVRYIRNK
FGDYFCIGVAAYPEGHSDQNHPLDQSLEHDLPYLVDKVQAGADFIMTQLFFDIEAYDHFE
KTLREHPSGTLKKIPILPGLMPIQSYQMIKRTTKLSHAKMPRHIMDRLDAVKGDDEKVKM
VGVDIIGDLIDQIRSIKDRTAGPKGFHFYTLNLEKAVSLIVEKAGFIPDADERDEAVLDD
HSLAPPVIQVNGNRTSSHSRTSRRRSSVGTDPYNRVIVGGRPATHPEWEATGQEAGVPAE
SINSRANTLAISEGEGVLGREATWDDFPNGRFGDSRSPAYGEIDGYGVSLHMSITQAVTL
WGHPKTRHDINDIFVRHIRGELAAIPWSEEGLSAESSTIQSRLIEMNKKGWLTVASQPAV
NGIPSGDATFGWGPKNGFVFQKAFAEFFLPSADWFILADKLKGSEYCDVVCFYAANCRGD
YVSSDVAAGVSSSRSVASSTNAVTWGVFPGKEIVTPTIIEEVSFKAWSEEAFGIWGEWAK
VYGRGSDSEKLLSGMRSDYWLVNLIHHDYIDKEALWNLLLDQGR
>A0A0A1UTX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium robertsii|TrEMBL
MDKITDKIAALPADREYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSKRLVDKALEDAKALGIRNILALRGDPPRKEE
YCDAEDSEDDGQQDFTWAIDLVKYIRRKHGDYFCIGVAAYPEGHSDESHPQDQSLEHDLP
YLVDKVQAGADFIMTQLFFDISAYDHFEKTLREHPSGAFKTIPILPGLMPIQSYQMIKRT
TKLSHAKMPPAIMDRLDAVRGDDEKVKLVGVDIVSELIDQIRKIKNRTPGRRGFHFYTLN
LEKAVSFIVERTGLIPRESDNEEALIDDGTLAPPAIQVNGTRASTHSRTSRRHSSVGSDP
YNRVIVAGQPPSHPEWEATGQEAGVPAESINSRANTLAISEGEGVLGREATWDDFPNGRF
GDSRSPAYGEIDGYGVSLHMSVNQAVTLWGSPTSRQDVNNVFVRHIKGEISAIPWSEEGL
SPESSTIQSRLVEMNGKGWLTVASQPAVNGISSSDRTFGWGPVNGFVFQKAFAEFFLPSA
DWHMLAEKLKGSDYFDSVCFYAANAKGDFVSSDISGGRSTRTVAASTNAVTWGVFPGKEI
VTPTIIEEVSFKAWSEEAFGLWGEWAKVYGRGSESEKVLSGIRSDYWLVNIIHHDFIDRE
ALWKLLLE
>A0A350V5T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVIEHLEKAKGAQKPLISFEVIPPKRGGDITQLFNVIGDVMKYEPPFIDVTSRAAEVEY
RETPQGIQKKVIRKRPGTIGISVAIKNHFNIDTVPHILCLGFTREETEDALIELNYLGIE
NILAIRGDDLGYHKPIPEYKSQNRFAYELIQQVNNMNCGRYLEEDLLDAKPTKFCIGVSG
YPEKHFEAPNMKVEVDHVKQKISSGGDYVVTQMFYDNKVYFDFVNRCREAGIEAPIIPGL
KVLTAKSHLFNIPKNFYINIPEELSGEILEAKDEHVMEIGAKWTAKQAEELLNNGAPSLH
FYIMQSAKPINKMFGHLKM
>G8TSS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfobacillus acidophilus (strain ATCC 700253 / DSM 10332 / NAL)|TrEMBL
MKPLAEALSHGLWLADGAIGTWFLSQGVEPHQLPLLPLDHPDLVIRCHLEYLQAGAQIIE
THSFSANRSKLAAMGWDGSVGELNRRAAQLARHARDIFGEPAYVLGSLGPLAVPVDSPIV
PGLDRAEAETVYREAVAGLLAGGVDGFLVETMSDLATVEAAVSAIRAESDLPIVVSFAFS
PLGTTLYGITPEAAVEAVMTLPGGPPAAIGANCGSGPSPLLDAVIRMAEKARTYQLPVVA
YPNAGEPALRDGHVHYPASPDYMATIAPALKAAGCAVIGGCCGTTPSHIRAIRQNMQGDL
HPQLTARPGWSLTEDVVPKSPDPEWSRPPRLVHELLAQQFVLSVELDPPRGPNLTRLVDA
ARQLEEEQVDVINVADSPMARVRLGALATARLIQERTRLATILHFTTRDRNLMGLQSDLL
GAFALGLTNILCLTGDPPGLGDYAHATAVYDLDSIGLTKVLAGFNQGLDALGQPLGSPTV
FSIGVGVNPTADPLEKEIERFRQKVAAGAHYAMSQPIYAPEQFYRFLDALGGPLPIPLIL
GIMPLVSYRQALYLHNEVPGITIPPEVLSRFESVQDGVHVGIELALELIQALRAGIHGIY
LVPSFNRVEPLVPLIREIRRLTR
>A0A844GNK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacterium aponinum 0216|TrEMBL
MTKLENAIASKEFIITAEVTPPKGGNPERMLEVARLLKDRVHGVNITDGSRAVLRMSSIA
SCVLLQREGIEPICQMTGRDRNSIALQADLMGAYSLGIRNILALTGDPLKAGDHPQAKAV
FELESVRLLKLIEQLNEGFDLNNKTLPDGNLNLFAGAAVDPQLKSWSGLQRRFEQKIKAG
AKFFQSQLITDFDKLDRFMNEIAKGCDRPILAGIFLLKSAKNAQFINKNVPGVEIPEHII
NRLEKAENPLLEGMTIAAEQIKDAQQICQGVHLMAVKREDLIPQILDLAKIHH
>A0A646MTM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii|TrEMBL
MAQLGALCISNLCATKPLSSAKGIAVPMSLAEFPCAITLADRVHADSDLAPLECAKTFPS
SMEKIIHYSGKGRDITDFETFLKSTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLESV
NAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALKQA
KAFLNRHRYPQNILACVMPLSLARANFMVKHKVAGIVITPHMLRVLAQEEQDGRTENAYK
RCAIQILMCKYLSFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVKTKN
ELVPELAYYSRQLSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASFWENAPAAKALL
KTEFISKQGIVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSV
KAQLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A1Y4TUE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp. An118|TrEMBL
MGKSMEKTDFREVFRAGRLVTDGAMGTYYREIYGGGGRFPEMDNVAAPERIEAIHREYIR
AGADILRTNSFASNTETLSQTWGEASREELLGKVYENVRAACHIAAGAVEKEAPGRPVYI
AGDIGPIPEHGSGDDEDGEEEILEEYRTIAKAHLDAGVKLIWFETFSDFKRILPVARWIR
SVSDAFVMASFSVNMYGYTNAGLSAAELVSIAKESQEIDGIGFNCGVGPAHLAKVLRRQD
FGDLVVFAAPNAGYADRIQDRNIYRDNILYFGEAMEEIAGLGVNIIGGCCGTSPAYIRQL
SRMPGGRMIPRRFTDRPEKRADKDISYNNNPFIRRLYSGEKVVIAELDPPHDGNDAKMME
AAAILKAAGVEMITFSDSPMGRMRADSAMSAVKVAGRLQVETMPHIACRDKNVIGMGAQI
LGAYMNGIRNFLLVTGDPVPSGERDVVTSVYDFHSVSLMKYLERMNREHFAQDPVAYGGA
LNYGRANLDAEIRRMERKCGAGASFFLTQPIYSDEDMERIRYIKSRIDTKVICGIMPLVS
YRNALFMKNEIPGISVPDGIVDRYDRDMSREEAQRVGVETAVEIAEKLRDITDGYYFMVP
FNRAAP
>A0A7X8RKZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. RO1|TrEMBL
MGILDSLAQDKILIADGAMGTLLYSYGSDCCFEELNLSHPNQIYNIHQAYLNAGANLIQT
NTYAANYHKLERYGLQDQVKEINSAAVRLAKKAVANHPDAHVVGTIGGIRAIKPEAIPLE
EIKRTFREQLYCLLLEGVDGILLETFYDLEELETVLQIARKETDLPIIAQVSLQEVGYLQ
NRVHITDALNRLESLGADIVGLNCRLGPYHMISTLEEVEIPKTAYLSAYPNASLPSYVDG
KLEYDSDAEYFKETALAFRDQGVRLLGGCCGTTPAHIQAFSQALQDVAPVKEKQVKRKER
TIIIPSKKKEVPTPLFEKAKKERSVIVELDPPRKLNTDKFMAGAQALKDAGIDALTLADN
SLASPRVCNTALGSIVKSDIGLRPLIHITCRDRNLIGLQSHLMGLHQLGIHDVLAVTGDP
TKVGDFPGASSVYDVTSFGLINMIKQFNQGVSLTGKELGERTSFSVGAAFNPNVRVIDKA
IERLEKKIDAGADYFISQPVFSEEKLLEVYQATKHIDAPIYIGIMPLTSSRNANFLHHEV
PGIKLTPHVLEAMNRHQNDPQQASIEGLNIAKGLLDAALELFNGIYLITPFMRYELTVEL
ANHAKKYGPFHSSRRVQNV
>A0A6N8J1D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramlibacter pinisoli|TrEMBL
MTFPISLEFFPPKTDEGAEKLRAARQKLYALRPEFCSVTFGAGGSTQDGTLQAVRAIMAE
GVPAAPHLSCIGQTRESIRERLAAYAAAGVQRIVALRGDLPSGYGSGGEFRYASDLVAFI
RAETGRQFQLEVAAYPEVHPQAKSPQSDLQAFVAKIEAGADSGITQYFFNPDAYARFMDE
LGRLGVRVPVVPGVMPITSSTQLLRFSDACGAEIPRWIRLRLQAYGDDSVSIRAFGLDVV
TQLCEHLRAAGAPGLHFYTMNQAAATQEICGRLAL
>A0A6G3ZUS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. SYP-B3998|TrEMBL
MKTDLRTALQRDILTGDGAMGTYLYQMGFPVGISYEELNLLRPETVEGVHRRYFEAGARL
IETNTFSANREKLSKYGLESDVEAINRAGVELARKAVGSDAYVVGAIGSIRAGKRKNVRT
ADVEQSLQEQIGVLLDSPVDGLLLETFYDLEELQLALRIIRSMSQLPVICQFANEGTGST
QDGVPLQEAFERLRDGGADVIGFNCRVGPNGILRSMEKLSPLVGVPFSAFPNAGLPDYVD
GHYTYAATPEYFAESALRFADLGARIIGGCCGTTPEHIAAVARALSGYVPAAPGAASAHA
EALRVSEPTPAKPAPLAAKPSLLDIVKQRKTVIVELDPPRDLDIDKFMQGSKALQDARVD
AITMADNSLAVTRMSNLALGYLVQDKLGARPLIHIACRDRNMIGTQSHLMGLHALGIDHV
LAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFVVGAAFNPN
VKHLDKAVQRLERKIEAGADYIMTQPVYDAKLIEQIYHATKHLDVPIFLGIAPLASGGNA
EYLHNEVPGIQLSDEVRGRMNGLKGEEGRTVGVEIAKELLDAAMPYFNGIYLMTPFLLYE
MCVDLTNYVWEKSERHDFHLYPLSK
>A0A8J6TYE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massiliimalia timonensis|TrEMBL
MNIANLFQSKKIVYSLEVFPPKKTSSVDTIYNTLYGLRGLPADFISVTYGAGGSDTQRSK
TCEIASLIKSEYQIEPVSHLTCLNSTKEDIRQTLDSLKANGIQNILALRGDKGPAVTPKN
DFTHANELAEFIKAYDPSFNVLGACYPECHCDSETIDQDIENLKLKIEAGASHLITQLFF
NNNHFYEFMDKAIQKGITVPISAGIMPIINKSQIERTVSMCGASLPRAFSTMINKYADDP
QALKDAGIAYAVNQIIDLISNDVRGIHLYTMNNVETASRITESIENIIKSQNRITKR
>A0A1X1QFE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cycloclasticus sp. symbiont of Poecilosclerida sp. M|TrEMBL
MKEETKQQFSFEFFPPKTEEGRVKLLNVSKTLGQLHPAYFSVTFGAGGSTQQGTIDTVVD
IKQQGFSAAPHLSCIGSTKENIREILSNYKSQGVDRIVALRGDIPSGTLDVGEFRYANEL
VVFIREETGDHFHIEVAAYPEVHPQATNAESDLLNFKRKVEAGANSAITQYFFNPDAYFR
FVEECANLSINVPIVPGIMPITNYIQLARFSDMCGAEIPRWIRKRLEGFGDDRESIKAFG
LDVVTSLCHTLLESGCPGLHFYSMNQAEASLAVWQELGLPQQKGK
>A0A0P9C426|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiohalorhabdus denitrificans|TrEMBL
MGFKRENYEFSFEFFPPKNDEGEKRLQEAVHELKPLNPAYCSVTFGAGGSTRERTFDTVD
WIQKEAGLEAVPHLSCIGSRKEDIREILQRYQDSGVKRVIALRGDIPEDEEAFKEGGFRY
ANELVEFIKSDFPSFEVVVGAYPEFHPEAPDPVTDMENFVRKVKAGADVATTQYFFTNLS
YYKFVDDVQKMGVDIPIKVGLMPITNFKQIDRFSQMCGADIPAWIRKRMEHFGDDTESQK
ELGIDIATRQAEDLLAQGIPGIHFYTLNKAEATKRIWQNLGL
>A0A4V2YYB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura darangshiensis|TrEMBL
MRCVWLKAHDRSRRLPGGAPWVDAVNATDNTAAHAHASNVAVAIALRGLGVEPILQVVCR
DKNRLAVQADIVGAALHGVTNVCCLTGDDVSAGDEPQSRRVFDLDGPQLVRVAAGLRRGE
YLSGRAITPPPELFIGAVENPSAPPHEYRVRRAQLKAAAGARFLQLQICFRPGRLEAFAA
LAERTGLTRRAALLQTVVLVRGARGLRFMDEHVPGISVPADVIDRVDRAADPAEAAYRLA
LEQARHALALPGVRGLHLADMRRDGSLARLVTDLGLGRDHHAHDPAIAR
>A0A0V8SZ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. (strain ADP)|TrEMBL
MTTSDRRFSFEFFPAKTEAGHEKLLATARQLAGYKPDFFSCTYGAGGSTRDRTLVTVLQL
DGEVNVPTAPHLSCVGDTKAELRALLAHYKDAGIRRIVALRGDLPSGMGMASGELRYANE
LVEFIRAETGDHFHIEVAAYPEVHPQARNSEHDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAQKLGIDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIASIQSF
GEQVITEMCERLLDGGAPGLHFYTLNQADPSLALWKNLKLPR
>A0A535QMG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MHPFLERLARGPLLGDGAMGTQLHAKGVSFERSFDELNLTEPKIVEEIHRAYISAGAELI
ETNTFGANRIKLARHGLDQRVRDINFRAVKLAREAREIAGEPIFIAGSVGPIGQQMAPIG
RITVAQATAAFEEQIAGLLEGGADLLVLETFTNLPEILAAVSAAKRSTDLPIVAQMTFAE
DGLTLSAEEPSQVVQALERAGVDVIGVNCGVGPQVALQVLEQMRQQTRLPLSGQPNAGLP
ARVEGRFFYFATPEYFATFARQAADLGVAYIGGCCGTTPAHIAAMRAALTPTTSPTRLRT
PSPSTAIAIDLNPAEQLPPTSFAQRLADHAFVISVEIDPPRGLNPAKCIAGAQLVKESGA
DAVNIGDSPMARVRMSALSLAVMIQQQVSIDTLIHFTSRDKNLMALQAELIGAHALGIRN
IIALTGDPPRIGDYPSATGVWDVDSIGLIKILQRLNEGYDWLGTSIGKPANFTIACAVNP
SAEDLDREIDRFRQKIEAGAHVAMSQPLYDRQTLERFFERTGSLPIPFLLGVLPLQSFRH
AEFMHNEVPGIVIPAQLRERMRLAGENGIAEGLAQSRELLHDTKALVQGVYLMPSFGRYE
VVAELVRWLRQERAPTLPSSRA
>A0A7C5EWT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKSGSRLERLLEAGHFVVTAELGPPKGPEVTVVERKMSLLAGACDAINVTDNQTAIVRLS
SAATCAILHQHGLEPVMQMTCRDRNRLAMQADIFGAVALGVRNLLCLSGDHQTFGNHPSA
KNVYDLDSIQMIQMVKRLRDEGLTAGGDAVEGQVPLLIGGAANPFGDPFEMRIIRLAKKV
AAGADFIQTQCVFDVARFKEWMRRVVDLGLHEKVAILAGVMPLKSAAAGRFINANVPGIT
VPEAIIERLSRAGRGAKAREEGMRLCAETIQELRTIEGVRGVHIMAVE
>Q5HS04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus epidermidis (strain ATCC 35984 / RP62A)|TrEMBL
MSHLLNQLKSNVLVADGAIGTIFYSEGLDTCPESYNLTHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKSFGLEHKVKEIHQAAVQIAKHAANEDTIILGTVGGFRGVRQEDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELTRIVTATRQKYDIPIIAQLTASNTNYLVDG
TEINAALKYVVECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDIAQELINEGVRLIGGCCGTTPEHIRYIKSAVKHLKPVKDKKVIPINKAS
SQKQTRVLKQNLTSKVKNGPTVIVELDTPKHLDTDTFFDNVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQRYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGINTDGDALKKHTNFNIAGAFDPNVRKLDGAIKR
LEKKVASGMSYFITQPVYSKEKIIQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSDDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A6N9JJS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GAATAPIAHMITSEFDTPSVAHLTCVGRSHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLTSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPTIAATIMERLG
>A0A7C3JZC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRGAGGRRSAALDRKDLFGDRVLVCDGAMGTMLQAAGVSLDLSLPELSVGRPELVRAIHG
AYIAAGADVIETNTFGACRTRLARFGLEDRVAEINAASVRVAREAVAAAERPVLVAGSVG
PATPASSRGRISPAVLREAFREQIAALAEAGVDLLILETFGSIGELVEAVGAAKEVAPEL
PVVAQMTFMDDGRTLAGETPAEFAARVEGLGVAAIGANCTHGPQGLYEILSELSRHTTLP
LAAQPNAGSPTFVDGRFQYPTDPAYLARYATRYVQAGAALVGGCCGTTPAHVEAVAAAVK
GLRPAVRRRSVSAQSAGGSRGVPGDHPQPSRLMQRLRAGEFVVVGEMSAPTGGAADRAVL
DAGLLEQEGASAVLIASPTSPRAQVSPTTLAVLLQQRVEAMDVILTVATWEKSVMSLQAD
LLGAYAFGVRHVVCRTGTPPLLGDYPNAGGFWDVDSVELIQLLRGLNAGRDRHGIPLAQP
TAFVIGARINPAAEDVEREIGDAARKVDAGVDFLITPPVFDVEALERLLDAARVPADLPV
LMGVMPLRDFNHVEYLQHEVPGMSVPEALVDRMWEAREDGAEAGRRIAAELIRQARDSKR
LRGVVLSSANNEAAELVNLVREVRP
>A0A8B3EFB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AM51-7|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSIIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIREVAKQIY
>A0A8J7YCM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomicroarcula limicola|TrEMBL
MSLNSLAASDAPGAETLLENVRFELMPFDSFDDEIQHLPEGATIAITTSPQLGIDRTIEK
SEMAAEKGFDVVPHVAARYVEDREHLEEIARRLTEAGVTDIFVPGGDREEPAGEFESAYD
LLTTLSETEYSFEEVGITGYPEGHEFLDEETLAEAMQKKEPYATYIVTQLCYDPEAVLEW
IRDVRDRGVDLPVEIGIPGVMNYKRLTQISQKVGVGDSIKFLKKTTGILGFVRQLIGSRG
TYKPDSLVDGLGPHADDESYNIRGLHIYTFNQTPDTESWRNGRLST
>A0A7C1FUH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSDAFLERLSRGPILCDGAMGTMLYQRTGTFEHCFDELNLSQPEWVAEIHRAYIEAGAEI
IETNTFGANRFRLAEHNLAHRVSDINAAGVRIAREVAALAGRPVFIAGSIGPTGVRLSPT
GSVTPDEVRAAFREQAAALADAGADLIIVETFSDLVEIEAAVRAVQDVCDLPIIAQMTFT
QDLRTPVGHTPEAVAQALAALNVPVIGVNCSVGPARVLTVTEDIRAALRAAGLDDRIKVS
AQPNAGWPEVSGGRIMYRATPEYFGDYARRFVLAGATIIGGCCGTTPAHISAMRLTLNAL
ALAPQRKEARVVVVQPPSRQKQPLPPEPPTQLARKLERGEFVVNVEVSPPKGFDPSRVLA
GALMLKQEGADVISVADSPRARLRMSPWAIAHLIQTQVGIETILHFPTRGRNLLRVQSDL
LAAHALHVRNLFVVMGDPPNIGDYPEATDQYDVVPTGLVRLIKRHFNQGVDQAGAPIGRP
CSFLVGVALNLSAQDVDKEIKLLRKKMESGADFALTQAVFDIRTVRAFLDRYHELHGPLT
LPLLVGVLPLASGRHAEFLHNEVPGMYLPEEVRRRMHLAGERGREEGIRMAQDLLLGLKE
LVRGVYIMPAFGRYDTAAEVISVLQQTAPPSAA
>A0A2J6JN61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactuca sativa|TrEMBL
MKVIEKILESTAAGDAGKVVFSFEFFPPKTEEGVENLFERMERMVAHNPTFCDITWGAGG
STAELTLEIARRMQNMVCVETMMHLTCTNMPVEKIDHALETIKKDGIQNVLALRGDPPRG
QDKFVQIQGGFACALDLVEHIRKSYDDYFGIAVAGYPEAHPEVIEGNGLATPEAYQKDLA
YLKRKVDAGADVIVTQLFYDVDNFLKFVNDCRQIGITCPIVPGIMPINNYNGFIRMTGFC
KTKIPSEITAALEPIKDNEEAVRNYGVHLGTEMCKKIMASGIKTLHLYTLNNEKSALAIL
TSLGLVDEAKITRPLPWRRPTNLFRLKEDVRPIFWANRPKSYISRTGGWEQYPHGRWADS
SNASYGALTDHQFMRPRARDKKIQAEWVVPLTKFDDISEKFMKYCLGQLKTSPWSDLDAL
QPETKIINEELASINLKGFLTINSQPAVNGAKSDSPSVGWGPAGGYVYQKAYVEFFCSGE
KLNALVEKSKAIPSLTYLAVNKEGTLVSNVGKNDVNAVTWGAFPGKEIIQPTVVDPASFL
IWKDEAFEIWSRGWAQLYPQEDNTSRSLLQEVQNTYYLVSLVDNDYINTNLFTVFKGF
>A0A535L332|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MEHLLLEQLQQRPLLCDGAMGTLLYARGVTYEQCFDELNITQPELIQSIHREYISAGAQI
IETNTFGANRVKLDGYQLGDRVREINSRAVRLAREAREISGQPVFVAGAVGPSGQPLQAP
NEQRLSELRGIFREQIEALLEGGADLLILETFSSLAELRQAVLAAQEAGGVPIVAQMSFY
EDGHTLSGQSAARVAAVLNDLGVNVMGTNCSVGPAATLDVMQEMISAVKQLGDDLQATPA
LFSAQPNAGLPTRIGNRFFYMATPDYFADYALRFAQAGVHLIGGCCGTTPRHIAAMRKAL
DAYYGISTQFPTVMVKETEEKVTETSNGPTTIAGLIEEEVILPRQGTPTRLQEKLASGEF
VVSVELDPPKGLNPTKILEGAALLQQAGVNCINIADSPMARVRMGCIAMARLIQDHLGLE
TIIHFTTRDRNLMALQSELLGAHALGIRNILALTGDPLRLGDYPNTTGVWDVDSIGLIQV
LRGMNEGHDAAGSSIGAQSCFHIGAALNLNMTEEETTQEIEKFRRKLEAGAHFIMTQPIY
ELAPLLRFLERVGKPSIPVILGCIPLHSSRHAEFLHNEVPGITIPEDVRARMRAAGERGH
EEGLKLAQELLSAARSMVQGVYLMPSYGRYDVVGKLTKMLLVQQTA
>A0A2E5Z7Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNSSFSERVFQGVLISDGAMGTQLHSRGGYNPNHSLDFLNITNPNLVKAVHLDYISAGAE
MITTNTYRANAPMLTSLGVGEQFNKINAAAVKIAQEARSLSGQQVWIAGSIGPPGKQTDL
FGASSLSNIANTVQDQADVLANNGVDLILLETFPSVADLTEAVSGIRKVTDLPIVAQLTF
MDDKQTPGGDTALDVVAALNESDVIAYGANCSVGPSLLIEILETMISTAKVPLIIQPNAG
FGSYQFGRLVYGSSPSYMAEMTSRMLEIGGTIVGGCCGTTPEHTAQIRDIVHFHKPGKKS
TSKKAAPKTEMTNRKQKQILEPTALAQSFKKGQFVVTLEVTPPRGFDFTPTLNKLRSVSN
SVHAFNVTDSPRAQGRMSALAAASIIQARLGKETILHLALRHRNLLALHGELLGAHALGA
RNIFTVMGDAPNSGDYPQATAISDVTPSGLIKILNGFNDGVDASGRPMEQATKFLIGCAL
DLNSNNMETELRNLDRKINAGADFLMSQPVYDPEKVERFRQRLGGFPLPLLLGVLPLRNT
RHAHFLDNEVPGITIPDQIINRLEKAEENASEEGYIISQEIIKNVRKSIAGVYFIPAFGQ
YDSVNSVMNID
>A0A3L7YI76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSINLQEKLNRGTLLADGALGSELYARGIKNGSCLDARNLTNPAAVLGVHASYLQAGAD
LIETNTFGANSFRLASHGHAEQVLVINQTGVALARQAAAASGRAVAVAGSVGPLGVRLVP
FGRVKPEAAYAAFCEQISALLAAGVDALVLETFSDLMELSEAVRAARACSTAQQPVLLVA
SMTFTRDDRTQLGDSPAHVARTLAGLGVDVVGANCSIGPAQLLRVLQAMHAAAPQLALSV
MPNAGMPEVSGGRVLYPAGPDYFAQLTPDWLATGARIVGGCCGTTPAHIAALRQALDTPR
AAAVHSAPARHSSPAEALPATDEPTKLATKLQSQQFVITVEMSPPKGYTPHKVLAGAHML
AESGADVINVADSPLARMRMSPWAVCHLIQQQVGIETVLHFPTRGRNLLRVQGDLLAAHA
LGVRNVFVVMGDPATIGDFPQAFDNFDVAPTALLQLVKQRFNAGMDQAGQDIGQPTSFVA
ACALSLSAPDPAREIKLLRKKLECGADFALTQPVFDAQVARNFFARYAAEHGALQLPVLV
GVLPLYSERHASFLHNEVPGIHIPEQIQHRIARAADAPAEGVRIALELIAELRATTPIRG
AYLQPPFRRYELAAEIIEHTRAQD
>A0A6L3EY91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNNEFKAGGRLERVLRSGRFAVTSELNPPDSADPEDVYRAALILSTVCDGINAVDASGAH
CHMSSVAICALLVRAGYEPVFQVACRDRNRIAIQGDLLGAAAMGVRNVLCITGDDVSAGD
QPEAKRVFDFDSIQLLQTAKTMRDESQFLSGRKLTTPPRLFLGAAANPFVPPHDWRPLRL
AKKIAAGADFIQTQYCFDVPRLKEYMKRVRDMGLHEKAFILIGVGPLRSDRAAEFMRSKV
PGVFIPDAVVERLRKTPKKQKKAEGKRICVEIIQQVREIEGVAGVHVMAYRQEELVAEIV
DDAGLLPRPRKTGASDPSVRARPKKA
>A0A433PEW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endogone sp. FLAS-F59071|TrEMBL
FLKLTNIYLYVKFAVIRKRYRESKSAQDRLPSERLGHDSKCHESSCGLKTDNHSLARHRL
SSTFRLEMKITDKIKKAQEEGVPFHSFEYFPPKTDQGVQNLFDRLSRMAQLKPTFVSFTW
GAGGSTFDRTIEMCATGQGVYGLETLMHLTCTNMGRDKVDMALKKAKEAGIQNILALRGD
PPRGQEYWSPCDDGFTYAVDLVRHIRSLYGDYFCIGVAGYPEGHTDAENIQDDQRYLKEK
VDAGADFIITQLFYNVEAFREWERKCRKDGITVPIIPGIMPIHSYLGFRRITNLVKSHVP
KEILDELEAIKNDDEAVKDYGIRLAVTLITSLQQSPGIIGFHLSTLNLEKSVRLILERLG
LVHKDEYLRQAQLQIAGKTAGGTAVAKVRYFTFEGWS
>A0A3N5GF78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPTHYHILVRVLQTSEVFKTSEVSDLEPPSELAQKLAAGKFVFAVEMDPPRGLATQKLVA
AASLLKEAGADVIDVADSPMARMRMSAWAVCDVVQRKVGIETTLHFPTRGRNLLRVQGDM
LAAHALGLRNIFVVMGDPTSIGDYPEATDNYDLVPSGLIKLIKQGFNTGVDHSGTSIGQP
TSFFAGAALNLCPPDVDSEIKNLKRKLKAGADFFLTQPIYDPDAARRFLDQFAAGNGSPL
DKPVLVGILPLVSVKHANFLQNEVPGIVIPEKTMERINQAGERASVEGVKIASELIQQIK
AWGQGVYIMPQFHRYDLVAEIIEKVAS
>A0A3A1YKP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga canis|TrEMBL
MKVTEHIARSKGKTLFSFEIVPPKKGNSIEELYQNIEPLIEFKPPFIDVTTSREEFFYKQ
HPNGLLEKKITRMRPGTVGICSAIQYKYGVDTVPHVLCGGFTKEETEYLLVDCFYLGIDN
VMALRGDARKEERYFEPTKDGHTYAVDLVRQIKDLGRGKFLHDVIETDYGTDFCVGVAGY
PEKHIESPSMTFDLARLKEKVDAGADYIVTQMFFDNQKYFEFVEKVRLMGIDIPIIPGIK
PITTKKHLNLLPQVFKLDLPEILVSELEKCKTNEDVKQVGIEWAIEQSKELKLWGVPTLH
YYSMGKSDNIVDIVSKVF
>C3RDJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei 5_1_36/D4|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEAQINDFNKGVFVDGSPIKITGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVEKVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A432K1B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSSDTGISSGFPNVSPSSYSEGTWPNCLPSTGSLFPSIYTGGAPVVKITEGSFEATGHT
SVICDFSPPRSGDAAVVGQAQIDADFISVAYNPGRAVRTNSAMLAAAIQNSGKDAVFTLA
TRDMNKLALQTQLLGAQLLGVQNVVVVQGDPFGERDQTRVASVNDYTPSGLIAAIAQMNQ
GQDFKESKLGQPTDFCIGATMDLGRGIEEEAQLAVRKVEAGAEFLITQPIFNVDHVARYR
ESFGYHAGKAGTVPIYLGLQILEKDGVLFSSVPESVRSELEDGRTGVDIALELYRKFQKA
RLNNIYLMPPIKRGGARNYEAAKEFLGKIKKA
>A0A2N2QGC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-7|TrEMBL
MKPEISIEFFPPQTPEGVDKLRAVRAELAKLHPSFFSVTFGAGGSTRERTFSVVKEIAAE
GHNAAPHLSCIGSTRDNIREILGEYRAAGIRRIVALRGDLPSGMAETGEFRYANELVEFI
RSETGNWFSLEVAAYPEWHPQARSPQDDLDAFVRKVKAGANSAITQYFYNADAYFSFVEE
TRARGVDVPIVPGIMPIVGFTKLARFSDACGAEIPRWMRKKFESFGDDADSIRAFGLDVV
TELCERLLKGGAPGLHFYAMNQSALTTEICKRLG
>A0A2E5EYT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKVFDNDITFSQLRRFVLMPSVTELLTQPRSRPFVVLDFSPPRGGIPHLLSDAFSLTPDL
FSVAYNPGKSVRANPIMVAHWIQNNTGIPAVFTLATRDMNKRALQGILLGAQLIGLDNVV
SVMGDELKGSEKLSQKTISDFTASGFVSSIKQMNTRVDFRDRFLRHPTGFCVGATIDLSR
DWSGEIPLTRKKVTAGADFFLSQPVFDTSQPEQFMERYFKETGCRLETPVMWGVQVKVQD
SVSLVPVPDWVHNDLEQGRSGFEIALQIISEHTDYGFDTFYLVPPILRGGTRDYESAQAV
IDEL
>A0A536I071|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
SLAAAHLLVEKGIEPIMQLAARDRNRLALQADLLGAAALGVRNILLMSGDDVTAGDHPEA
RSIYDIDSLQLVQVARNLRDRGTYLSGRRLESPPVFFVGAVENPFAPPLDFRPFRLQKKV
EAGAEFIQTQLVFDLTRFHAFMARVEDLGLLERVFVIASIGIPRSARGTHFMKEKVPGLS
VPDDVIRRMESVPPLQQPAEGIRIAIELVEAVRSIRGISGVHLIGIKWEEGVVRVAQGAG
LLPRPVAEVVATVGGGA
>A0A1H6RKR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter koreensis|TrEMBL
MTKVTEFITQAQGKTLFSIEIIPPVKGQNINELLNGIEPLMEFKPPFVDVTYHREELIDV
VGQGGLIERIPIRKRPGTVGICARLMERFKVDAVPHVICGGFTKDETEDVLFDLHYLGID
NVLVLRGDPEKSAGVFKAKLGGHSYASELITQVANMNKGILLHAETEASHTDFCIGIAGY
PEKHLDAESLDTDFEHLKRKIELGANYIVTQMFFDNQKYFRFVDRCRSEGITVPIIPGLK
PLATKRQLTVLADIFHLEFPQDLIDEAQKCATDKEVRQVGIEWSIQQCKELIAYGAPVLH
FYTMGKSDNIAQIAGKFF
>A0A535MUV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLARSRPTVSFEFMAPRDESEVDVLERTVATLAGHGPDWVSVTYRVRTGEKTLEL
VTRIKRHYHIEAMAHLTCANTADRTRQILNWMEREGVANVLALRGDAPVSGEPFTPADPQ
LTHASDLITLVRRSGYRFGIGAACSAEKHPESPDLEHEFRYLHLKVESGADFLITQLFFD
NKFYFDLVTRVRAAGITLPIVPGLMPIPSRRSLGVMTSMSGASVPAALQSAIDEAPDDEA
IRALGVQHCITQCAELLETGVPGLHFYTFNRARAPIQILAALRGQQLLAS
>A0A432JC72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSSDTGISSGFPNVSPSSYSEGTWPNCLPSTGSLFPSIYTGGAPVVKITEGSFEATGHT
SVICDFSPPRSGDAAVVGQAQIDADFISVAYNPGRAVRTNSAMLAAAIQNSGKDAVFTLA
TRDMNKLALQTQLLGAQLLGVQNVVVVQGDPFGERDQTRVASVNDYTPSGLIAAIAQMNQ
GQDFKESKLGQPTDFCIGATMDLGRGIEEEAQLAVRKVEAGAEFLITQPIFNVDHVARYR
ESFGYHAGKAGTVPIYIGLQILEKDGVLFSSVPESVRSELEDGRTGVDIALELYRKFQKA
RLNNIYLMPPIKRGGARNYEAAKEFLGKIKKA
>A0A535DGY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSTFTQLLRRGDFVVTAELNPPKSAAAQVVRRRASILKGYVDAVNVTDSNRAVAAMAAIP
AAVIARETGVDPIVQITGRDRNRIALQADVLGAAALGIEHFVFMSGDDPKQGNHPDAVNV
KDLDGIGLVKMAASLRDKAQFLSGDEIKEPPQYTIGATASPFTKPMESDLTKTTEKIAAG
ADFIQTQPVFDLATFSQWLAEVRRLAGRHVAILAGVLVLRGAEQAERLAKVPGLALGTHV
VERIRAAEDQEGEGIAIAVETAKSLRSLPGVNGIHLYAIEWPQGVTKVVRAAGL
>A0A248LFU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Laribacter hongkongensis|TrEMBL
MSATPTISFEFFPPKTDEGRAKLATACKQLARFKPGFFSVTFGAGGTTREGTLRTVLDIR
AEGHAAAPHLSCIGSTRDNIRAILDEYRAHGIRHVVALRGDIPSGMGGVGEFRYANELVS
FIREHYGDHFHIEVAAYPEYHPQAGSAQADLDAFARKVKAGANSAITQYFFNADAYFRFV
DEAEARGVGIPIVPGIMPIYNFSQLARFSDLCGAEIPRWLRLKLAGYGDDVHSIRALGLD
VVTDLCDRLLSGGAPGLHFYTLNAAGSISTLCQRLGL
>A0A2W6BF09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MHRPREGDSQAVTRPGPSQERELLLNRQSQGTLVPAAREGQNALVEALLRPRFELVPIRG
VEDQARHLRSGTTVTITSSPTRGIENTLMVAKQLSAQGLRVVPHIAARLVVDEVHLRDLL
QQLSDLNLREIFVIGGDAKKPAGKFTGALDLFRAMANCAHDLEAIGVAAYPEGHPLVNDR
ILLQALRDKQPFATYMVTQICFDPEVTVAWLAKIRSQGIRLPVYIGLPGIVGTKQLLQIS
MKIGVGDSLRFLSKHTSLAAGLFARNGYHPDDLLEYLAPYLDLPEYKIRGLHINTFNQVE
STEAWRQKMLTIASNS
>A0A2E3AMD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPSVTELLTQPRSRPFVVLDFSPPRGGIPHLLSDAFSLTPDLFSIAYNPGKSVRANPIMV
AHWIQNNTGIPAVFTLATRDMNKRDLQGILLGAQLIGLDNVVSVMGDELKSSGKLSQKTI
SDFTASGFVSSIKQMNTRVDFRDRFLRHPTGFCVGATIDLSRDWSGEIPLTRKKVTAGAD
FFLSQPVFDTSQPEQFMERYFKETGCRLETPVMWGVQVKVQDSVSLVPVPDWVHNDLEQG
RSGFEIALQIISEHTDYGFDTFYLVPPILRGGTRDYESAQAVIDEL
>A0A497C2F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTDEKFKSGSNLEKVLLAGHFAVTGELGPPQGADPEEILHKARLLEGIVDAVNITDNQTA
VVRMSSIGSGVLAMRAGLEPTVQMTCRDRNRLAMQADFLGAYALGIRNLLCLTGDHQSFG
NHPTAKNVHDLDSVQLIRMVKDMRDKHIFQCGDEIKAGSPRFFIGAAINPFADPFEFRPY
RLAKKIAAGVDFIQTQLIYDIPRFREFMKKVVDMGLHKKVYILAGVGPLKSSGMARYMRD
KVPGMIVQDEYVDRMVAALKGIPKEEKKARRAALRKKGIEICIEQIQEIREIEGVAGIHI
MAVEWEAAVRPIVEGAGLLPRPTVT
>A0A3D1TTB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSCPCKDPSDTPATSCLSKRDRPCPAVSGPPLGQDASRWLRFFKVFPRPKHFEKGALTVK
LREIYATPGHKLSFEFFPPKSDEGLEQLMGQVEILRTLNPSFCSVTYGAGGGTREKTVDL
VSTIRRKHGLEAMCHLTVVGQSKTEVREVLSDLRQRGIENIIALRGDPPRGVSEWSPHPD
GFKYSVDLVREAKSHGSFSIAVAGFPETHPQAESPEADLQYLKAKVEAGADLIITQLFFD
NDDFYGYVERVRKLGINVPIVPGIMPILSAEQATRFATQCGAKIPQKLRNRLERLTDDSD
GAVQLGIEYATEQCEQLVGFGVPGIHFYSLNRSRSVSAIVKNLALDEMAAGNVT
>A0A7J7T181|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pipistrellus kuhlii|TrEMBL
MDLPNPEVLPAGHCCPSLGTRALEAGIMRFSVPPSISRHSAMANEPRGNGGPNPRLEGSG
GGMESSKDSSRCSSPGLDPERHERLREKMRRRMESGDKWFSLEFFPPRTAQAAVNLISRF
DQMGAGGPLFIDVTWHPAGDPGSDKETSSMTIASTAVNYCGLETMLHMTCCRQSQEQITG
HLHKARRLGLKNILALRGDPVGEQWEEEEGCFRYARDLVKLIRSEFGDYFDICVAGYPKG
HPDAESLEDDLKHLKEKVDAGADFIITQLFFEADTFFHFLKACSRMGISCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQKIRDVIEPIKDNDDAICNYGIDHAVSLCQELLASGLVPGLHF
YTLNRRMATTEVLKRLGMWAEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQD
WDEFPNGRWGHSSSPAFGELKDYYLFYLTSKAPREELLRMWGEELTSEESVFEVFVHYLS
GEPNQSGCPVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRDTVGALLQVLKKYEQRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWVEKWGKLYAEGSPSRMIIQDIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLHRPGTRGDRLRDPVP
>A0A836YVV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei EFB6|TrEMBL
MSLQYSFEITPNIDQVNLDGLLKLHPEFISITDRNHDMDNLLQSIQIADYIHANSSVDVV
IHLTGIDKDEKGVQEMIDLMQQHNIHSVLALRGDKLSQNDTAVTFPHADRLVEFIKQQYP
HVNISGTCYLNSSDEEMKWLRQKIEKGCTNLISQFSFDANDYVDYLNQNQIDTPIWFGIM
PLISRSQAENMLSLTHSTAPDELNALMNQYKDEFGEGGVRYTAGMINKIKQAGANHIHLY
SLNNAENTEKIINII
>A0A1C7EJN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus donghaensis|TrEMBL
MGLIDELKTRILTADGAMGTLLYSYGIEYCNEELNLQRPEIVEKIHLDYIKAGADIIQTN
TYGANALKLARYGLESQVAEINKAAIEIANRAAAPGGQFVFGTIGGIRGIRKSDASLQEI
IAMVDQQATHLLEGNPDGLLLETYYDFEELAATVKHLKSITNTPLIAQVSMHDPGILQNG
MSLNDALHQLESLGADVVGVNCRLGPHHTIQAFEEVTLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGRAALLLREEGVRLIGGCCGTTPKHIEAVKKHLGQLAPIVHKKVTERKPIV
IREAEALEVKPLHEKAKTERTIIVELDTPRHLDVTKFLEGSVALKAAGVDAVTMADNSLA
SPRISNMAMGSILKHTEDIRALAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKKLNEGISFSGKSLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIESGADYFISQPVYTKEKITEIYEATKHLEAPIFIGVMPLTSIRSAEFLHNEVPGI
KLSDDALARMRACGDDKDRATEEGIQIAKELIDTAAELFHGIYLITPFVRYDMTVELIHY
IRQLDQQKESDRNHVQASY
>A0A415VNH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM22-16AC|TrEMBL
MNLREYLKETNLITDGAFGTYFAAKYQTQEIPELANLSDPEKVKKIHEEYLNAGANFIRT
NTFAANTETLQESFPEVEKNIRAAVEIARSAAEGKNVWIAGDIGPIPVNGTEDAAAAADE
YYEIAKTFAETGVKVLDFETFADLDGILPAIKKIRAEYDMFIAVSFSVNQFGYSAAGLSA
KRLLADAAAVPGIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPVYFAEKMKELQELGADILGGCCGTDPEFIREMFAWDGILKKGAPEKEAESSGQSEH
VVRQGFLYDENGNRKEKKLIAVELAPPFDVDDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMANKVRQATGLNVMPHICCRDRNAIAMRSLFLGAAINDIYNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTEGDAVRLRRIKDETGARILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKASRKEGEAVGIQLAKEVMKLVEDFADGYYFSFPFNRVYMLKDICNCSVGLRTCCAN
RNKTQA
>A0A7X9TB17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parafannyhessea umbonata|TrEMBL
MRIADILKSKQTFSYEIFPPKGDMSVVQATGIAERLMQNSPDWISVTFSAGGSGNSQNTV
SVAKAIQASGTTQALAHLTCLGSSRADVDAYVQKIQAAGVQNVLALRGDRAPGRDVIDFE
HASDLVAYLKRTGLCVGAACYPEGHLESPSLQADIEHLKAKVDAGADFLVTQLFFDNEDF
YRFRDRCSRAHIKVPIVCGIMPFTSVQQIQRMAFTCGASIPAAVIKRLVAAGDSKQAQQD
AGVAYACEQLVDLARNGVDGLHVYTMNRPSVADATHDCLLQAGYVEA
>A0A8F8I6E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. S7/73|TrEMBL
MLRSETARHNGEIRGDIRLSFEFFPPKNPEMENQLWETVAELKKWDPDFVSVTYGAGGST
KAPTLDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIG
TDYRPHPQGYENAAALVKGLRDISDFEVSVSAYPEKHPESASDAVDIDMLKRKADNGATR
ALTQFFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPSFLDERF
AGYDDDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSA
A
>A0A1B2DTI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. BIHB4019|TrEMBL
MNSKPDLRSAIAERILTGDGAMGTFLYQMGFPVGVSYEEFNILRPDVIENVHRRYYEAGA
QVIETNTFSANLEKLSIYGLEAEMEAINRAGVRIARAASGPDAYVVGAVGSIRAGKLKNT
RTVRVSDAYERQMAALLTEGVDGFMLETFYDLDEMLLALRIARKLTDIPVICQFAVEDVG
RTQDGVSLKQAFDQLTEEGADVVGFNCRSGPNGIMRAMKAIEGEATWPLSIFPNAGIPDY
VDGKYTYAATPEYFAASAREFADYGARIVGGCCGTTPEHVAAMAAALNHYSPQSGSQAVA
GTAVLEAETIVINEQPPLKLEIPDVRIPSEPNIVDTVRERHTVIVELDPPRDLDISKFMA
GAAALKACGTDAVTMADNSLAVTRMSNLALAALVQEKVGLRPLVHIACRDRNLIGTQSHL
MGLDALGIDHVLAVTGDPARFGDLPDSSSVYDFTSFEMIRMTKQLNEGIAFSGKPLKQKA
NFIVGAAFNPNVKHLDKAVQRLERKIKSGADYIMTQPVYDPALIKQVAEATKHLPIPVFI
GIMPLASGRNAEYLHNEVPGIQLSDEVRQRMAGLEGEAGRAEGVRIAKELLDEAVLHFKG
IYLITPFMFYDMAVQLTEYVWEKTGVHR
>A0A813BL02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiodinium microadriaticum|TrEMBL
MAQQLEGHQKISDLVTQVLMHALGPLFSDFASGPSSTPERALQLTSKAKNHFGVLAGMHL
NCTNKSSEMTGNALLKCKQRGVHGHPLGTAGGFSSALDLLKFIRQNHDDYFSVSVVDSDA
KFMVRFSDVGKTVLAMIYAGRPMRCLGRLLAHPRLRGGGPPGSRGRDTARPTRSSASPRS
LREWPLSEWQKQSLRKLDLKRQALPEDGDCFFHALALHSELSPSALRARVALEVESNAEF
LRLFPDRQALRSHVSGIRTGEWADHISVQDRGPRRPEGDHRRLGSCRHRDLRHSPPGDAL
RRSLPRIPRHCAMQRWGQGWRRS
>A0A429IFE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC 06783|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVQHPEGVLYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATQLCARLMAEGSPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A2D4WHN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium|TrEMBL
MNQTIINKPISFEFFPTKTDAGHAKLIAAGHALAAEKPEFFSVTYGAGGSTRDRTRKTVL
QLDSEVKVATAPHLSCVGDSLEDLRTLLGEYREAGIKRIVALRGDLPSGMGQASGELRYA
NXLVEFIRQETGDHFTIEVAAYPEAHPQAPHFEADLKXFVRKVXAGADSAITQYFFNADC
YFHFVERARKAGVEVPIVPGIMPITNYSKLARFSDACGAEIPRWIRXQLESXGDDSQSIX
SFGTXVISQMCERLLEGGAPGLHFYTLNQAXPSLDILRXLQXG
>A0A2E4VMC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium|TrEMBL
MTNRNIPINFEFFPPKTEAGQAKLVAVANVLADEQPEFFSVTYGAGGSTRDGTRRTVLQL
NNEVGVPAAPHLSCVGDSREDLRTLLNDYRAQGIQRIVALRGDLPSGMGHASGELRYANE
LVEFIRAETGDHFKLEVAAYPESHPXAPNXETDLXNFIRKAXAGADSAITQYFFNADCYF
HFVDRVRQAGVDIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSDSIKAF
GTEVISQLCERLIEGGAPGLHFYTLNQAEPTVAVLRNLRG
>A0A1H1KSZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parafannyhessea umbonata|TrEMBL
MRIADILKSKQTFSYEIFPPKGDMSVAQATDVAERLMQNSPDWISVTFSAGGSGNSQNTV
SVAKAIQASGKTQALAHLTCLGSSRADVDAYVEKIKAAGVQNVLALRGDRAPGRDVIDFE
HASDLVAYLKQAGLCVGAACYPEGHLESPSPKADIEHLKAKVDAGADFLVTQLFFDNEDF
YRFRERCSRARIKVPIVCGIMPFTSVQQIQRMAFTCGASIPAAVIKRLVAAGDSKQAQQD
AGVAYACEQLVDLARNGVDGLHVYTMNRPSVANATHDCLLQAGYVEA
>C0G779|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella ceti str. Cudo|TrEMBL
MMGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGST
RERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIG
EKYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATR
AITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERF
DGLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAA
LEVA
>A0A127PI39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas fungivorans|TrEMBL
MSQKNAQKNFSIEFFPPKTPEGAEKLRVTRAKLAELHPRYFSVTFGAGGSTQKGTLDTVL
DIRGEGHEAAPHLSCLGSSRESLRTILTQYKDHGIKRLVALRGDLPSGYGAMDISSGEFR
YANELVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDVQRFVSKVKAGANGAITQYFYNA
DAYFRFVDEAQKLGAAVPVIAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDSDS
IRAFGLDVVTQLCERLLAGGAPGLHFYTLNQSPATIAIWQRLKL
>A0A1B8QZH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus sp. CCUG 60358|TrEMBL
MSYANEINTLNQHLADTNKKINVSFEFFPPKNEKMESMLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGIEAAPHLTGIDATPEELKEIAKDYWDSGIRHIVALRGDEP
KGYAKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIEAEIVPGILPVTNFKQLQKMASFTNVKIPAWLAKAYEGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHTLGIRPTANP
>G7W6Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus orientis (strain ATCC 19365 / DSM 765 / NCIMB 8382 / VKM B-1628 / Singapore I)|TrEMBL
MAEEKSKLQSLFEQGEFAVTCEIGPPKNAQGDGIRKHTEHLKPFVDAVNLTDNQTAIVRL
SSIGAGVHVLAAGGEPIIQMTTRDRNRIALQSDLLGAYSLGVRNVLCLSGDHQAFGNHQG
AKNVYDLDSIQLIKTVKDMREAKVFQSGEAIKQGEPRFFIGAVANPFADPFEFRVLRLEK
KIRAGAQFIQTQCIFDMERFEAFMDLACKRGLHQQAYIMAGVMPIKSAKAAKYMQKNVSG
MLVPDGIVERMSKAEDQPAEGVKLCIEQIKHLRTIPGVRGVHIMAVAWEEIVPEIVKGAG
LLPRP
>A0A7X9VL07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. RLA2-12|TrEMBL
MALGSASTRTDRARTVRDMLGTGKATYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDVDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCTTPVIPEVMPVTSVKMLERLPKLSNASF
PDVLKERILTAKDDPAAVRSIGIEFATEFCARLLDQGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A4Y9VND0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera oryzisoli|TrEMBL
MKTTTKKFDVSFEFFPPKTTEGMDKLREARNQLAKFNPEFFSVTFGAGGSTRDRTMDTVL
EIQREGFQSAPHISCISSSKAEIRDLLHAYQAQGIKRLVALRGDIPSGEVSAGDFRYASE
LVAFIRDETGSHFSVEVAAYPEFHPEARTPAADLLNLKRKVDAGANSAITQYFYNADAYF
RFVDQCDALGITVPIVPGIMPIYNITQLARFSSVCGAEIPRWLKMRLEEYGDDIASLRAF
GVDVVSELCETLLAWGVPSLHFYTLNQSNTISNIIENVQD
>A0A2D7HKQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula sp|TrEMBL
MSLASHFTTSRCAISFELFPPKTEAGLKTLCDNVKRLKQFDPAFFTCTYGAGGSTQGATL
DVLQKVRELTDLPVASHLTCVNSTVAELESFLRQAKQRGIDYIVALRGDPPQGTAKFEAV
DGGLQYANELVELIRDQFEFGIAVAGYPEVHQEAPDAQTDLDNLKRKVDAGADVIITQLF
YDNANFFRFRDRCNTAGITIPIVPGILPVTNFKQATRIARMCKAAIPEKLTSFMNATEDA
AEQFQIGVEHARAQTLDLMSNQVPGIHYYVLNKSDAAAALLDGMQTTQSA
>A0A2T1KBG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter fuscus|TrEMBL
MESQKQFKRRFSFEFFPPKTEQGKEKLQTVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRQEIGELLDVYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLESYGDDTTSIRK
FGEEVITEMCEKLLKAGAPGLHFYTLNQAQPSLSIWENLGISDREKIAF
>A0A5E4ZFK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea anapnoica|TrEMBL
MNGTHDNKTIMTQPSFSFEFFPPKTADGAQKLRATREQLFPLGPKFVSVTFGAGGSTQQG
TLDTVIEIQREGVDAAPHLSCVGSTRDNIRDILTTYRDHGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGDWFHIEVAAYPEYHPQAKSPRHDLEHFANKVKAGANAAITQYFF
NADAYFRFVDDVARLGVDVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
EAIRAFGLDVVSALCERLLKEGAPGLHFYTLNAAAATKAMWQRLGL
>A0A1H1T4R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella sediminis|TrEMBL
MFKTSSFTKMINSEQHVTIKNNNGKHMKVTDHIKNANGKTLFSFEIIPPKKGNSIQQLYN
NIDPLMEFNPPFIDVTTSREEYLYIEKEGLLDRKITRMRPGTVGICAAISHKYNVDTVPH
VLCGGFTKEETEYLLVDCHYLGIHNVMALRGDAMKHEQYFKACDGGHKFAKELVGQIQNL
NKGQYLHDVIEVDGKSDFCIGVAGYPEKHLEAPSLKTDLKRLKEKVDAGADYVVTQMFFD
NKKYFEFVDAAKAEGITVPIIPGIKPLAVKRHLQLLPQVFKIDLPEDLIDAVDGCKTNQD
VRKVGVEWAIQQSKELQEAGVPVLHYYSMGKSDNVKAIASELF
>A0A2S7WP65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter porphyrae|TrEMBL
MKITDHIKNANGKTLFSFEIIPPKKGNSIQQLYDNIDPLMEFKPPFIDVTTSREEYVYIE
KEGLLDKKKTRMRPGTLGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMSHQKYFEASAGGHQYAKGLVSQIQNLNCGKYLHDVVETNNCADFCIGVAGYP
EKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFAFVDAAKKAGINVPIIPGIKP
IAVKRHLQLLPQVFRIDIPETLISEVEKCKTNKAVRQVGIEFAIRQSKELLAAGVPVLHY
YSMGKSDNIHAIASELF
>A0A245ZN26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas dokdonensis|TrEMBL
MTLSINQLEEARHALEAPLFADVAGDIDVSFEFFPPKTEAMDATLWQSIATLAPLGPRFV
SVTYGAGGTTRERTHATVARIARETNVPAAAHLTCVEATRDEIDAVAEEYWAAGVRHIVA
LRGDPPRAGERYAAHPGGYENAAALVEGLRRLHPFEISVACYPECHPDSNDAVADLDNLK
RKIDAGATRAISQFFFSPDVFFRYRDAVAAAGLDAEIVPGVMPVSNFAAVQRMSAMCGTE
VPAWMGRLFNGLDDLPAARQLVSATLAAELCRKLYAGGVKQFHFYTLNRAELSFAICHLL
GVRAQADEGRAAA
>A0A1E5GFU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus ureasiticus|TrEMBL
MRTDTLFKEKTVFSYEIFPPRRTAPIDTIYHTLDRLKGQQPDFISVTLGAGGTGANFSTA
DIAQKIQEEQFLPSVAHLPAVNFSKDEILVILEELKQKKVENILALRGDLLPDKEPKKDF
VYANDLVAFIQEQGDFNIIGACYPETHGDAESSVEDIRNLKRKVDSGTNQLITQLFFDNN
YFYTFKEKCAIADINVPIQAGIMPVVNKKQIERMVKMSNVTLPTKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVAQGADGIHLYTMNNPYVAQKIREATRSLFSA
>A0A0C2CQQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enhygromyxa salina|TrEMBL
MLIRDRLAHKRPVFSFEFFPPNNEKGERVLWRSLEQLAPLEPDFVSVTYGAGGSTRTRTV
EIVGRIKRELGIEPLAHLTCVGSTRDEIEAVVERLLEAGVRNILALRGDPPRGQTQFQHT
PGGFRYASELCAWLRDRWPELCVGGACYPEVHPEADTAEADLQHLRAKIDAGAEFLISQL
FFDNAAYFGFLDRVRGAGLSVPIIPGVMPITNVKQIDRFTKMCGATIPSVLRSRLDDISE
TTDGYDPQEVFWTGVSYAAHQCRELLDRPSNGPFRRQASTVSGIHFYTLNRSPATRALFE
ILALARAVH
>A0A2G3PJR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Williamsia marianensis|TrEMBL
MSSQQSHPSIVQRLAEPHPGPVPFSVEFYPPRDEQAEARLWRTVRIFERMGPAFVSMTYG
AGGSTRDRTLRITGQLARETTLLPVAHLTAVGHSVAELRAMIGGYADKGITNILALRGDP
PGDPLGEWVKHPEGVEYAEQLVRLVQELGDFNVGVASFPEGHHRAPDLDHDTKYLVSKLR
AGAQYSITQMFFDVDDFLRLRDRVTAMDPEQGAKPLIPGIMPITSLASVRRMVELSGSVL
PEAVDRRLAAAAGDGSEENREAVRAVGIDLATEMAQRLIDEGVPCLHFCSLNFAKATSEV
LERLGMNVMAA
>A0A4R4NJB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura bangladeshensis|TrEMBL
MRRARPDRAPTVRELLASGGRSFSFEFFPPKTDKGARNLWRTIRELESLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPDGVEYAAELVRMIRSYGDFCVGVAAFPYKHPRSPDVDSDVRYFIEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDVPILPGIMPVTQMSTIERSEQLSGAPFPPEV
KARFEAVADDPEAVRRLGVEHAAELCRELLEQDAPGIHFITFNKSTATREVYSLLGAGEY
GARGSVPPMTA
>A0A3M9Y8Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium nonalfalfae|TrEMBL
MDKITDKIAALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
AFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPPRKAE
YQDAVDGESDDGEDFVWATDLVKYIRKNHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVEKTQAGADFIMTQLFFDIDAYDHFEQVLREHPSGAFKTIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDALMARLDAVKGDDEKVKEVGVDIVSELVDQIRAVKSKRTTGPQGFHFYTL
NLEKAVSFILERTNLIPDKEQEDEEAVIDDATTPPVVPTVQINGLHPGSHHRPGRRQSSI
GSDPHNRVIVSSASNHAYETNPEGAGLPAEPINTRANTLAISEGEGVLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVTQAVRLWGHPKSSVDISTLFIKHIRGELSAIPWSEE
GLSPETNIIQEQLIELNTRGWWTVASQPAVNGVPSRDATFGWGPSHGFVFQKAFVELFLP
AADWKVLSERLTGPEVEGTVCFYACNGNGDFATSDDSGGLVRTAVPASTNAVTWGVFPGK
EIITPTIIEEVSFRAWSEEAFKIWGEWSRVYGRGHESEKFLKTVKDEYWLVNIIHHDFVE
TNALWDLLRG
>A0A7J4I7R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon|TrEMBL
MKIHQLYQPEIKVFSAELMPLPNGSVISDFDALVEPLRAVECRYFTITQPAPSTPKSGTP
VIAHYLERKYSQKVIVHLTGGCHTPKELENKVQELSYLGIENVLALRGDPQSSSNGINRS
GLDVVRQLATLRRGRYIHRDILTPYDFSLAVPCYPEGHPLTTKEHCWDDFKQKVEAGADL
AFTQAVFLPEKYQQLQEWAQRNKITIPIIPGIFIPRTPNDFSFLQSKRVGVAIPSKLLAL
AERFSASPFSFEAAVDDFIFSLAASLLQSAPGAHFYSLNRTDRVAKIMSGIS
>A0A7K2HAS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4936|TrEMBL
MALGTPSTRTDHARTVRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATEQIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVKHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFNPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFAQLSNASF
PSSLKERILAAKDDPAAVRSIGIDFATQFCARLRSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A7X7ZBI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriales bacterium|TrEMBL
MKVIEHLEKAKEPFISFEIIPPKRGGDMKSILQVIDDLSKYNPPFIDITSHAAEVIYEET
SSGIKKKVIRKRPGTLGICALIQNKYNIDAVPHLLCKNFTREETEDFLIELNYLGIENIL
AIRGDDSGFTKPVPAGRSANYYALDLVKQVKAMNNGHYLEENLLDAFPTNFCIGVSGYPE
KHFEAPSLKTDVKYTKMKIEAGADYIVTQMFYDNKHYFNYLEMCRAEGIGAPVIPGLKII
TIKPHLTNIPRNFFINIPDELVDEVMEARPEHTMEIGVNWAAKQVTELLEKGAPSIHFYV
MQNTAPIKRLMAKLKLDKNNFFVTK
>A0A835MGU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salix dunnii|TrEMBL
MKVIDKIRAAAAGGDANASANGNGCDSSSNSNVVFSFEFFPPKTEDGVDNLFERMDRMVS
HNPSFCDITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDQALETIKSNG
IQNVLALRGDPPHGQDKFVQIQGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDMIGS
DGFATLEDYHKDLAYLKQKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMP
INNYKGFIRMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTVH
LYTLNMEKSALAILMNLGLIEESKITRPLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRT
IGWDQYPHGRWGDSRNPSYGALSDYQFMRPRARGKKLLEEWVAPLKSVEDIYEKFKVYCL
GKLKSSPWSELDGLQPETKIINEHLGKINLKGFLTINSQPAVNGEKSDSPSVGWGRPGGY
VYQKAYLEFFCSKDKLNAIVDKCKSFPFVTYIAVNKGGSWISNVALTDVNAVTWGVFPAK
EIIQPTVVDPASFSVWKDEAFEIWSRGWASLYPEGDPSRMLLEEVQSSYFLVSLVDNDYI
HGDIFAVFADL
>A0A6L9KLU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax sp|TrEMBL
MTATSPIPISVEFFPPKTPEGVDKLRGVRQQLYTLKPEFCSVTFGAGGSTQEGTFNTVRD
ILAEGVQAASHISCIGATHAKVREQLGILKAMGVRRLVALRGDLPSGFGIGGEFHYASDL
VEFVRAETGDDFHIEVAAYPEIHPQARSPAADLQAFAAKVKAGANSAITQYFYNADAYFR
FVEEVDALGLSLPIVPGIMPIASSTQLMRFSDACGAEIPRWIRLRLQNFGDDVASIKAFG
LDVVTDLCLQLRAGGAPGLHFYSMNQSAATLEICHRLG
>A0A443S0N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrombidium deliense|TrEMBL
HILETLESISDNKTAVKKFGIDFAVNVCEEIIRSGLCPGFHFYTLNNESSTITVLKKLGL
WKRSIPKALPWRVIPSSKRYKERVRPIFWSNRIRSYLYRTSDWLIYPENKWNDYAPQVYK
EVDDYFYKYLDNYDSEEELKNLWGNELNSLNDVYDVFGHYFSGKENKNGFKVTKTAWTQN
KFDNSDKLTTFSEQEFLTINFQLNLNGVDSSDEKVGWGPKGGLIYRKAYLEFFTSRQNAM
ILKDLLLKYKQVNYNIINSDETENYTNCDEDKAIAIDWAAFPGEPIMQPTVADPISFKVW
KNEAFSLWNEWAKLYEEESKSKRLLEYISNDYFLVYLIDNNFPNECCFWKLLEEVHLISK
YSEQLSI
>A0A6J6HBS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTYGAGGSNRERSLAVVDRMAAKVLTIGHLTCVGATKQSTLEILQHFERAGVGAILALRG
DAPKDDPDALGKGELKTALELVDLVHESTKLEVGVAAFPEVHPESPNMEHDSKVLALKQD
AGATFAVTQLFFSVQAYTDLVASAQAAGVTVPIIPGVMPISNAKQVVRMAELSGAAIPAE
LIAKFDAAADEDEAREIGMAYSTQLAKDLVTAGAPGVHIFTLNHHAAAIELARGAGLCR
>A0A7D5RMY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospiraceae bacterium|TrEMBL
MKVTDYIHEAGXKTLISFEILPPLKGXSIQTIFKAMDPLMEFKPXFIDVTYHREEFLYQM
QPTGYYQKTSIRKRPGTVGICAAIMHRYGVEAVPHLICGGFNREDTENALIDLHFLGIQN
VLALRGDARRFEDKFSPEPDGHHYAVDLIHQITGMNNGSYLDTNIEKGSRTDFCIGVAGY
PEKHFESPNLELDIKHLKAKIDAGGNYIVTQMFFDNKVYFDFVKLCRENGITVPIIPGLK
PLTKLYQLNSIPRNFYVNLPNDLVREAQKAKTDEDLKQIGIEWCIAQSRELVENNVPCLH
FYTMSDAQVVKKICSKIV
>A0A6J7I2I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVVRTSYSLEFFPPKDSEGEARLWATLEALKPMAPEFVSVTYGAGGSTRNRTIGVTEEVT
HRSKIPTVAHLTCVGSSRQELISILHMYRAAGIRGILALRGDPPGGPRAAWTPTSDGFTH
ADELVQLIHEFGGFDIGVAAFPDGHPSSEGDSKKDLDVLLRKEFLGASFATTQFFFEVSK
WEQLVYSLEKRGSTMPIIPGILPITNVKQLERMAELGGTPIPPAVSSAFSTIGDDPDAVH
ALGIELATKLCEDLLSAGAPSLHFYTMNSATATKEIYGNLNHAH
>A0A2N2UZ51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-11|TrEMBL
MSFELSIEFFPPQTAEGAEKLQLTREKLAALNPAFFSVTYGAGGSTREHTLATVGAIAAV
GCTAAPHLSCIGSTRAGIRELLERFRALGLTRLVALRGDLPSGMADPGEFRYANELVSFI
RRETGDAFHIDVAAYPEWHPQARSPAEDLANFKRKMDAGADGAITQYFYNLDAYTHFVAE
ARALGIGAPIVPGIMPIASFAKLARFSDACGAEIPRWMRKRFESFGDDAASIRACGLDVV
TELCQRLLDAGAPGLHFYSMNQASLTLEICRRLGRG
>A0A371BMD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. RT-1|TrEMBL
MSPPSLIDAHPNLTDAAPVALSYELFPPRSAAAAETLWTTIRELETTAPDYVSVTYGASG
SNRDTAVELIHRLLLETTLRPIAHLTCVGNTPQELAGIIGELLDIGARGILALRGDQPKD
GGQPAEGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEEHDIEVLL
AKQRSGADFAITQVFFDAEQYVSLLTRARRAGVTIPIIPGVMPLTSLRRVTRLGELAGVE
PSPDLLERLAAADNDIERLRIGVRATVDLANAALDAGAPGIHLYTFNEHQSALEVLDKLA
LPRHQRAASRHSVAARPQLAS
>A0A2K9LC35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MQAIELSIEFFPPQTPEGAEKLRTVRDRLAVLQPAFFSVTYGAGGSTRERTFATVQEIAA
AGFEAAPHLSCIGASRAQLRAILKEYEEAGIRRIVALRGDLPSGVGTAGELRYASELVEF
IRAETGRRFILEVAAYPEWHPQAKSPRDDLLAFQRKVAAGADSAITQYFYNLDAYLHFVD
EVRALGIDIPIVPGIMPITSFAKLARFSDACGAEIPRWMRRKFESFGDDSASIRAFGLDV
VTDLCQRLLDAGAPGLHFYCMNQAEPTLAICERLGLGPHAR
>A0A4U8SFK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. MIT 11-5569|TrEMBL
MESQAIESFMQKLQNGAKCYTYEFSAPASFNLDVLFETLKQQKFLQNIDAFVCTDSPLGK
LKHSAVLASLKLQNAFKIPSIATISMRDKNTLALQSELIGMNSLDLRLVLALTGDPLRLG
NQPQAKGVFEGSSALLLKIICALNASKDINGGNLQGESKSIYPFCVLNSYAKNKENLYRK
MCEKIQNGALAIFTQPIYDINIAEELLEWCAKINAQYNKKCVLMFGFFPITSYKTAFFLH
HKLPGVFVPKDWLIALENASKEGNEEQIGLQKSQALFKDLSALQQRFHFMSANKPDVIKK
ILEN
>A0A559LTR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. cubense|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDDVKGDDERVKMVGVDIVSELIDKIKTIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A4S1FNT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M4B.F.Ca.ET.143.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVVREFADMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKSAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A4U0V6V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Friedmanniomyces endolithicus|TrEMBL
MHITKKLAQAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGFGPAFIDVTWGAGGRMS
HLTCEMVKVAQSAYGLETCMHLTCTDMAQSKIDGALDEAYKAGCTNILALRGDPPREKEK
WEQSEGTAFRYARDLVKYIKDKYGNHFDIGVAGYPEGCDDETDADAHIPYLKEKIDAGGT
FVLAQMSYDVDIFMDWVKKCRQAGIPESVPIIPGVMPIQTYDSFLRRAKWTQCRIPKTWL
DQLEPIKNDDAQVREVGKDLVADFCRKLLDSGTTMHLHFYTMNLAASTRMVLDELSVAPA
ADSHNPDLKPLPWRQSLGFNRRDENVRPIFWRNRKQSYVARTQDWDEFPNGRWGDSRSPA
FGSLDAYGIGLKGTNEHNRKLWGEPKTAQQVAELFVGYMSGKVESLPWSEAPISSEADTL
RHDLIDLNSRGLLTINSQPAVDGAKSSHATYGWGPKNGYVYQKAYLEVLIHPAILPKLIQ
RMEEKEEITYYAVNHSGELKTNVSSDGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEF
YHLGLEWSKCYDEATESRRLIREIAESWYLVNIVDNDYRDSRGIFPLFDGLRVDGVDVKT
KSITNGDANGTSHVNGSIKEEKEGKAPPETNGVPDKNNTVNGADLKAAPTMMAKN
>A0A1J5C4I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium CG2_30_59_46|TrEMBL
MTTPLPILSFEFFPPKTPEGMDKLRATRKQLAQLNPEFFSVTFGAGGSTRDLTLETVIEI
QREGHEAAPHLSCIGSTRENIRAILNEYKSHGIRHIVALRGDMPSGMACAGEFRYANELV
EFIRAETGDWYHIEVAAYPEFHPQAISAQADLVNFKRKVEAGANAAITQYFYNADAYFNF
VDECQAMGITIPIVPGIMPIGNFTQLARFSDACGAEIPRWLRLKLQGYGDDTAAIRACGL
DVVTSLCDRLLKGGAPGLHFYTLNQAGLISTIWQRLGL
>A0A0G2HMI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Synechococcus spongiarum SP3|TrEMBL
MKSQVSSSAFQQALASGQPVMTAEISPPRGGSVQHVLATADQLRGRVHALNVTDGSRAVM
GMSSVAVCRLLLERNLEPVLQVGCRDRNRIALQADLLGAHALGLRNVLCLTGDPVKAGDQ
PRARPVFDYEAVRLLRDVKNLNRGLDALGRPLPDGPTALFPGCAADPQSPSWSGLKSRLQ
RKKEAGARFIQTQMITDLAALRRFCRELAAPLGLPVLAGVFLLKSGKNARFINRMVPGAS
IPDAAIARLDGARTPWAEGLRMAAEQVAAVLEITQGVHIMAIKAESAIPQILDLAGVPPL
APPVVGGVDLRALAAEPC
>A0A5P9PVT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. YIM 10|TrEMBL
MKSLREELAGGRRTFSFEFFPPKTEVGERRFWDSVRRVESLAPTFVSVTYGAGGSSRERT
VSMTEAIVADTTLRAVAHLTAVGHSVAELRQIIGQYAGAGIRDVLVLRGDPPGDPRARWI
AHPQGFTYAAELVAMVKEIGDFSVGVAAYPELHPRSSDVDSDTRYFVEKCRAGADYAVTQ
MFFDVTHYLRLRDRVEAAGCTTPIIPEIMPATDFKQIRRFAELSDASFPPELARALEHAT
PEDAYRIGVDHATAMAERLLAEGAPGLHYITLNKSDAALDIHRRILGSTARRAA
>A0A1Q8B7Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_20CM_2_55_15|TrEMBL
MARNPLRECLQSRRFCHVVEIVASRISREARLLEVASQLATTPGVVAGSITSYAGGAPGQ
DPVRVGTAARARGLTPNIHVTCVSKDRQELRHYLETIAGLGLENVFALTGDYPKDANAVF
DLDSVQLITLMNELRRQGLPFWIAAAVSPFKYTEPDCAYQYLKLEKKFKAGADYAITQLG
FDVRKFRELRRYLDERHIQNPVLGNVYVLGLKSAEKMSKGEPPGCWVAPELVVKIRDEVK
AKDKGEAVRLERAARMIAILRGLGYAGAYIGGTHNAEHLRWIIERGQILAPRWKELADEF
TYAPKSAFYMFEPGPAAPRKLRGLSDRAVNALWHLLSPTQIPRGSILEKWARAMFAWIDR
RPTMSRFLERAEFAIKSPAFGCETCGNCVLPDMQYVCPQTC
>R8I3B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VD021|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRATLNVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7U7EU35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus (strain MRSA252)|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A7R9WQJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Craspedostauros australis|TrEMBL
MTTTANADTKIIDLLKQNKDESKPKISIEFFPPRTEVGVKNLHARMDRMKNAIDPLFTDM
TWGAGGSTAELTLDLSAHSRKAGHVSNMHLTCTNMEKDGDPKKAVHDALQTAQDNGIRNI
VALRGDPPAGQDEWKAAEGGFACALDLVKYIRENFGETFGISVAGYPEGHPNAISEIEDP
STMSEAEKARSSTFDGKVYTCKDEDYKKEMDYLKEKIDAGSDFIITQM
>A0A1I6QBK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. 103mf|TrEMBL
MKLLDLLQRRIVIGDGAMGTLLYSHGLQSCFEELNLSEPERIISIHKQYVAAGADVIQTN
TYGANEGKLRMYGLEDRVRKINRAAVRHAKEAVTEKNAIVGTIGGMKHIGAVTTTDMERE
FMLLEQANALLEESVDGLLLETFYDEFELLHAVKVLRKQTNVPLIAQLALHEASTTQNGN
SVDDVLKQLIEYGANVVGLNCQLGPLHMIESFKTIEIPKYSYLSAYPNAGLPKYVEGRYV
YEGSPAYFEEMAPEFIKQGVRLLGGCCGTTPSHIEAMKRALENEHPVTAKEVVKRVEVIA
KPRVNTVDRITLAEKAKKETTVIVELDPPKTLDTQRFFEGAKALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPILIHLTCRDHNVIGLQSHLLGLAALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNNGRSILGKTIGAATRFSVGGAFNPHVRHIEAAVKRM
EKKIAAGAEYFLTQPIYDAAVIRNVYEATKHIEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRRRMDGHKTSEEAVAEGIRISKELIDAAMELFNGIYLITPFLKYEVTETLVQYIQ
ARKEQKEGMNI
>A0A2Z3MYJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga alhagiae|TrEMBL
MKVTEHINQAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPSYINVTYHRSEHMFKKR
ADGSFDKVEIRKRPGTVGICAAIMNHYSIDAVPHLICGGFSKEETENALIDLSFLGIDNV
LVLRGDAPKNETFFEAHPNGHRYALELLNQVVHMNNGIYLEEDLQGGLKTKFCIGVAGYP
EKHFEAPNLQTDLGYLKRKVEGGADYIVTQMFFDNKKFFDFVNRCREAGITVPIIPGLKP
LTTKKQLTVLPRTFHVDMPDELAEEALKCKTDKEVEVVGTEWLIQQSKELKAAGVPVLHY
YTLGKPHVIHKVVSTIR
>A0A527GWL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQIDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRSYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPESVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A528EA58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDASRHQVDAVIREFAGFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDAQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHESEAA
GSAAA
>A0A1E5PQ14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces subrutilus|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATEQIASDTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMAEWVAHPEGVHFAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
ADVKERMLAVKDDAAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A5R9J7I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lichenicoccus roseus|TrEMBL
MRISIELIPRGETELLRDAGTARSVMPEAAAFNIPDLMRFPLRSWEACRLTSSILPASIP
HIRAIDIPPGDDLPMEDAILAAGLGEVLVIRGDPPHDMGHRTYPNSSEDIIRRFKRRCPG
LRVYAAFDPYRLGFRDELTAVHRKLDAGADGFFTQPVFDLRLLEMCAEMLHGQTVYWGIA
PVLGARSQAYWETTNRVIFPAGFTPNLSWSRTFATQAVQRVREIGGHVYFMPIRVDMASY
LTGLLG
>A0A3C2ERS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dialister sp|TrEMBL
MSTLKEKNQNHIFTITTELDPPKSASSAITEEQAQKVAPYVDAVNIADCPMAKMRMSPIA
LSCIIQQKYQVESIFHLTCRDRNVIGLQAELLGAAALGVHNILTLTGDPPKIGDHPNAKG
VFEIDSTGLIQIASCLNSGHDIEGHDLGAATDFYIGTTGNPGTDDLDAEIKRLEGKKKAG
AQFIQTQPIYDIKQAEDFLACAKDLDLPILFGIVPLKSFKMANYLNDKVPGITIPKKVLS
QMETGGRETGLAISKEIVTALREIHAAGAHLMPVNDIDAIPYIVGDK
>A0A3S3QFU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycicoccus flavus|TrEMBL
MAQHGGGGRPAHLVASIPDRLRSPRPSISFEFFPPKDDAAEASLWDAIRRLERVRPAFVS
VTYGAGGTSQDRTVRVTARIADETSLTPLAHLTCVDQSRRELRRVVGHYADSGIRNVLAL
RGDPPGDVGGSWTPHPDGLAHAEDLVRLVRGLGDFTVGVAAFPDVHPDSPDLDHDVDVLV
RKADAGATFAVTQMVFDADTYLRLRDRVAARRDLPVTPGLMPVTSYRQIQRMSELMGTPL
PPTVVERLEAVKDDTRAVRRVGVEIATELGRRMLDEGAPGLHFITMNRSTATLEVHEALG
L
>F3LV31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax benzoatilyticus JA2 = ATCC BAA-35|TrEMBL
MSTTPVSFEFFPPNTPVGADKLRTVVQDLAAVNPEFFSVTYGAGGTTRERTLDTVKAIAA
MGHEAAPHLSCVGSTEANIAEILATYREQGIRRIVALRGDLPSGTATAGEFRYASELVEF
IRRTQGDDWFIEVAAYPEYHPQQRYARRDLEHFANKVGAGANSAITQFFFNPDAYFHFVD
EVHKLGVRVPIVPGIMPIHNYARIAQFAARDGIEIPRWVALKMEGFMDDTASVRAFGIEV
VTRLCERLIAGGAPALHFYTLNQSSLSLEICRRLGLAQDA
>A0A2D6CKD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MSTRTDISQSLSQGASETAERLARRPKPKALLLRDTPRVSFELFPPSTPEGQTGFFDTAD
QLDVLGGTFMSVTYGASGTSQARTLNALQTLTSRCTTPMAGHLTCVGAAKEAVMAVVEAY
STAGVGQVIALRGDPPRGRSTFQPHPRGFSSASELVSAISHRGGFDIGVAAYPEVHPEAH
SGKDDLDNLKRKIDAGARYAITQFFFEADTFLRFRDRAVAAGIHAPIIPGILPVVNLKRT
ITMARTCGTHVPAWVASLFDGLDEAPRVRTLVSATIAAELCTRLRDQGVDRFHFYTLNRS
ELAWAVCRMLGLRAVERAQPCRSAAASHA
>A0A1N6H6W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces cerinus subsp. cerinus|TrEMBL
MASTATDASGADCRPRLPLSFELFPPRTDAAALALGRTIDRLAEVDPAFISVTFGAGGSS
RARSLTVLRYMLEHTHVEPMAHLTCVGSSHAEANRLVREFLDAGITSFLALRGDPPADAD
PDAGIGDLGSAAELVQLIHRVQEEREPFGQVGVPGNPGASRIRARPRPERVAVAAFPTGH
PRSRNLGHDVDTLLAKEIAGANLAITQLFWRADDYLGFVERARAGGVTIPILPGIMPVTN
PARLSRLTELTGVEPPAELAIDLEIEPDAAGQTELGIAFATRLAAEVIAGDAPGLHLYTF
NRHEAVLDVVDRLGLRTDRFADERNTAR
>A0A327V3C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PsTaAH-137|TrEMBL
MRPTFSFEFFPPKTAKGEQTLWQALRRIEPLAPDFVSVTYGAGGSSRERTVQVTQRIVAE
TTLRPVAHLTAVDHSVAELRHIIGQYADVGVRDVLVLRGDPPGDPRGPWRPHPDGFTYAY
QLVELVRSLGEFRVGVAAFPEMHPRSPDWDTDIRHFVAKCHAGADYAVTQMFFDVEDYLR
LRDRVAAAGCDTPIIPEIMPATDARQIGRFAELSGAAFPEDLAHRLEASRDRPHDAYEIG
VAHATAMAERLLAEGAPGLHYITLNKSTATLDIHRAVLNSSRSLHVS
>A0A259BFZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halothiobacillus sp. 24-54-40|TrEMBL
MTIPLSCEFFPPKSDDGAAKLRAITTELATALCPEYFSVTFGAGGSTQERSFATVSAIQL
ESGVPAAPHLSCIGSTRAGIAAILDQYQALGIKRIVALRGDLPSGMRDPGDFRYASELVA
FIRQHSGDGFHIEVAAYPEFHPQSLNAKADLQHFKHKVDAGADGAITQYFYSIEAYSRFV
DDCDKRQITIPIVPGIMPINNYTQLARFSDACGADLPRWLRKRLEAFGDDMDSLRAFGHE
VVVNLTADLVRVGAPGLHFYTMNQAAPIIALCQDAGVHPA
>A0A528B5V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPYDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHLLHDEITETQVDMVK
TAH
>A0A530LIF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
ARTVKRILNETTLTPAAHMTCVDAARHEVDAVIREFADMGVKRFVALRGDPAEGVGAAYR
PHPEGYANGAELVDALKGAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRAITQ
FFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFDGLQ
NDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEVEAAGSA
AA
>A0A529VIS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
AFMQSARDLGHTEKVFILCGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEG
KQLCIDIINEVKEIPGVAGVHVMAYRQEEYVA
>A0A239PZR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amphiplicatus metriothermophilus|TrEMBL
MSELYVSFEFFPPKTSQMQERLWSSIARLAPLEPDFVSVTYGAGGSTRERTHETVARVLK
ETSLSVAAHLTCVAATREEVDDVLRAYWEIGVRHIVALRGDPPGGPGEPYRPHPGGYANA
AELAAGARNIAPFEISVGCYPEKHPDSPSLAADIDMLKRKIDAGASRAITQFFFDNDVYF
RFVERARAAGVGVPIVPGIMPVSNFAGLRKMADICGATIPGRLVKLFQNLDEDPATRQLV
AATVAAEQCLALAEQGVRHFHFYTLNRDELAYAVCHMLGVRPKPARNADAAA
>A0A7Z9QF31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIEFLEKANKTLFSFEIIPPTRGGSIDRVFNLVEALIPFDPPFIDLTSRSAEVYYEDA
GEGKMIRFIRRKRPGTIGISAAIKNKFNVETVPHILCRGFTREETEDALIELNYLGINNV
LAVRGDELRKDAPDSPGKTRHRYASNLVSQIKDMNDGKYVEELIDAAPTNFCIGVGAYPE
KHFEAPNMATDIKYLKAKLDAGADYIVTQMFYDNSAFFKFVDDCRSAGIDVPIIPGIKIL
STEKHLSVIPKNFYVDIPEALSEKVIGQSKKDIVNIGVEWALEQVQELVDAKVPCVHFYI
MSSAKSAAKVVSQFK
>A0A251V117|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helianthus annuus|TrEMBL
MKVIEKILESTAAGEAGKVVFSFEFFPPKTEEGVENLFERMERMVAHDPTFCDITWGAGG
STADLTLEIARRMQNLVCVETMMHLTCTNMPVEKIDHALETIKKDGIQNVLALRGDPPRG
QDKFVQIQGGFACALDLVEHIRKSYGDYFGIAVAGYPEAHPEVIESNGMATPEAYAKDLA
YLKRKVDAGAEVIVTQLFYDVDNFLKFVNDCRQIGITCPIVPGIMPINNYNGFIRMTGFC
KTRIPSEITAALEPIKDNEEAVRAYGVHLGTEMCKKIMASGIKTLHLYTLNMEKSALGIL
TNLGLIEETKISRPLPWRRPTNLFRLKEDVRPIFWANRPKSYITRTAGWEQYPHGRWGDA
SNASYGALTDHQFMRPRARDKKIQEEWVVPLKKFDDISEKFMKYCLGQLKTSPWSELDAL
QPETKIIDEQLASINLKGFLTINSQPPVNGAKSDLPTVGWGPAGGYVYQKAYVEFFCSGE
KLNALVEKTKAYPSLTYIAVNKDGTLVSNVGKNDVNAVTWGVFPAKEIIQPTVVDPASFL
IWKDEAFEIWSRGWAQLYPEDDSSRSLLQEVQNTYYLVSLVDNDYINGNLFTVFSNF
>A0A838BML1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga mediterraneensis|TrEMBL
MSPLALRPSRQNASPIKVSFEFFPPKTPEMETTLWSSIQRLAPLHPHFVSVTYGAGGSTR
ERTHATVSRILKETPLKPAAHLTCVAATKEEVNDVVRSYRDAGVRHIVALRGDPVGGIGT
AYEPHPGGYRQACDLVAGIKAIGDFEVSVSAYPEKHPEAASLDADIDALKSKVDCGADRA
ITQFFFDNDLYFRYLDRVRARGIDIPIVPGIVPVQNFKQTANFASKTGASVPGWLAARFE
GLENDVETRKLIAAAVAAEQVFDLLDRGVNEFHFYTMNRADLVYAICHLLGLREQSVRAA
A
>A0A7Z9J226|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRFRDKVRKPKRPVVAYEILPPREQDGTLNSYAEKISSLLSQTHIDAINIPEVHDESVRG
KRPVKNQKRAEAREFGRLLQDNVGIEAIVNRVTVNHELNYQKKWIKETYYDYDIENLILV
GGESSKINYPGPSVNNTSEYITRDLNTGRFDFFCGGITIPSRKTESAKLFRKGSNGIEFF
TSQVLYNGNKIKKMLKHYDDICEKNGVMPRRILLSFAPVSSKKNIDFLKWLGVEIPENTE
HRLNQDPENMSNVSLEIASEILKDILQNNEEKEISVPIGLNVEHIMSYNFQSSINMLQKL
SRIYREFCIKTSLYD
>A0A8I0M3H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYKAAGIQRIVALRGDLPSGMGMASGELRYANDL
VNFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A3G2JPE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces dangxiongensis|TrEMBL
MTGKDTPGLEEARDAIPPGTRINITFLAGEDTVTRLAAARAVGRLGFVPVPHISARRLPS
RPALEEFLAGLAADGTAENVFVVGGDPARPEGPYEDALAVLRTGPLRQHGVRHVGITGYP
EGHPGIPGPVLWTALTRKAAAIDAHRFTGDVITQFGFDVDPVLTWLEELRARGVHLPVRI
GVPGPAGVRRLLGYATRFGVGTSASVARKYGFSLTNLVGTAGPDRFLRALADRYDPERHG
VVKVHFYTFGGLRTTAEWITRFRRERAV
>A0A7Z6QSR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLATYHPDFFSCTYGAGGSTRDRTINTVLQLE
SEVNIPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISNMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>Q3ACR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)|TrEMBL
MVTAEIGPPKNSNGEVVRKHARNLKNYIDGANLTDNQTAVVRLSSIAAGFHVLSEGVEPI
IQMTCRDRNRIGLQSDLLGAYSLGIRNVLALTGDHQSFGNHPTAKNVYDLDSIQLIQTIK
KLRDEKQFLSGEPIKEHEPRFFIGAVENPFGDPFEFRVLRLEKKIEAGAQFIQTQCIFDM
ERFERFMEMVRERGLHERAYILAGITPLKSAKAAKYMKNVAGMIMPDHIIERMEKAEDQK
EEGVKIAVEMIEHLKNVKGVAGVHIMAIAWEDIVPVIVERAGLLPRPEV
>W4RJ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesobacillus boroniphilus JCM 21738|TrEMBL
MDCCGTTPEHIKAFADELKGLPPVLDKKIPAKKPKIVVTPVDVKRPLAPLQQVVKERPSV
IVELDSPRKLDTTRFFEGAKALKDTGIDALTLADNSLASPRISNSAIGHLVKEKIGLRPL
VHLTCRDRNIIGLQSHLMGLHTLGLHDVLAVTGDPARVGDFPGASSVFDVSSFELIEMIK
QFNEGLSYSGKDLGQKGAFSIGAAFNPNVRSIEKAVMRMEKKIHAGADYFITQPVYSEKM
LLEVHEATKHIDAPVYIGLMPLTSSRNAEFLHNEVPGIKISQEILDIMAKFNNEPLQSKK
EGIAITKGLIEAAAELFNGIYLITPFMNYEMSVELSGYANEYSSRLMRRKQNVNLVN
>A0A166NPZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARHLATFNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLSQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EHVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>R5T6J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium hathewayi CAG:224|TrEMBL
MKTTDLFAKKPVLSFEVFPPKRTNPVETIYETLDSLRKLNPDFISVTYGAGGSENCKATT
EIASKIKNEYGIESVAHLPCIGLTKDDVISLLGGFKRAGIDNILALRGDIPEGGRPAGDF
EYASDLISFIKEKEEFKDFNVVAACYPEGHTESVNILTDIRSLKTKVDAGADHLITQLFF
DNDCFYRFKERALLAGIHVPVEAGIMPVTNKKQIERMVSLCGVSLPSKFTAMMERYEHNP
EAMRDAGIAYAVDQIVDLIARGVDGIHLYTMNNPYVASKIHEAVYRLLAA
>A0A2E6JIE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MXITDYIKXTNKTLFSYEIIPPFRGGSIXKVFKLVEELMPYDPPFIDLTSRSAESYXQDD
GRGNLIXHIRRKRPGTIGISAAIKNKFNVETVPXIXCNGFTKEETEDALIXLNYLGIXXI
LAVRGDELRQSKKLEKDNIYNXYASDLVEQIQKMNDGKYLENLVDPSKTDFCVGVGGYPE
XHFEALSXXSDXEKLKYKVDXGADYXVTQMFFDNKHYFKFVXQCNKIGXKXPIXPGIKIX
SLERHLEALPKHFXLNLPKELIKSVEGKSKSEIRNSGIDWAISQIQELIXKXVPCIHFYI
MSSAKSATKVVSNFI
>B0A8W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Intestinibacter bartlettii DSM 16795|TrEMBL
MSKLREAFEKGEFAITAEMAPPKGTDLSHLAECAKLVIGRVHAANVTDNQSAVMRTSSLA
TCKMLKDLGLEPVIQMTGRDRNRIAIESEMLSAGFFGIDNLLALTGDHVCVGDHKQAKPV
FDLDAVSILSTATMMNNGTDSTGLELKGKTDFFLGACVTPEYDPIEVQLLKMEKKIKAGA
KFFQTQAVYDIEHMRKFRELTKDMDCKVMAGIVPLKSPGMAKFMTANVPGIFVPDDQIER
LKAAGKGNYVAEGIKMAGEFIKQLKEENLCDGVHIMAIGAEENVPLILDAAGL
>A0A371X7J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fulvimarina endophytica|TrEMBL
MLKPRPTSQPIRVSFEFFPPKTEKMEETLWQSIERLAPLAPEFVSVTYGAGGSTRERTHQ
TIQRILRDTALVPAAHLTCVDASREEVDEVVRQYRETGVRHFVALRGDSQLGVGEEWQGR
SDGYRNGAELTEGLKRIDPDFEISVSAYPEKHPESPDLTTDIDLLKRKVDAGATRAITQF
FFDNDLFERYVERVRRAGIYIPIVPGIAPVHNFTKIANFAAKAGASIPDWVRTRFEGLED
DPLTHSHVAAACCAEQVLDLTERGFSDFHFYTMNKADLVYSICHILGLRGASADVPPALQ
SAAA
>A0A5E8GYG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium alexandrii (strain DSM 17067 / NCIMB 14079 / DFL-11)|TrEMBL
MTVLSSRLSRGVIKTPITASFEFFPPKSEKMGETLWETVQRLAPLNPSFVSVTYGAGGST
RERTHKTVERILNETDLAPAAHLTCVGSPKAEVDAIVKDYWDLGVRHLVALRGDPLAGIG
AVYEPHPEGYAYATDLVEGIKKIANFDVSVSGYPEKHPESGSWQKEIDNLKRKVDAGADR
IITQYFFDNDLFDDYLDRIAAAGINIPVIPGILPIHNFEQTMVFSAKCGTSIPEWVARRF
AGLQNDPETRKLVGVAIACEQVMDLVDRGLTDFHFYTMNRADLTYAICHMLGMGQHGTEK
VAA
>A0A0A7IAS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum PV8-2|TrEMBL
MFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAEYG
IPAVAHLTAQYLTEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAFIR
ERRPDMKIYGACYPEKHPQADTLDHDIDNLKRKVDAGVTHLISQLFYDNSDFLRFLDKAR
AAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDHWQDDPNTLKTAGILYASE
QINDLLARGVDGIHLYTMNHPCVTRRIWTNVQDLFA
>A0A2D9HLF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEKIANYKAQGKTFYSFEFFPPKTDFGLDNLYSRIDRMASLQPAYIDITWGAGGSTS
NKTLEMCKTIQKYFGLEVMMHLTCTNMQVSSIKKVLIEAEKNDLSNILALRGDPPEGSSS
WEQHEDGFRHGVDLVRYIRKEFGDHFFLGVGGYP
>A0A386YFI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMAVAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEANIPAAPHLSCVGDSKADLRGLLTQYQQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISSMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1C7NCB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Choanephora cucurbitarum|TrEMBL
MKVIDKINKAEKEGRAFWSFEYFPPKTEMGVQNLYDRMERMQRFGPEFVDITWGAGGTSA
DLTIDMVASAQSVYGLETMMHLTCTNMPVEQIDRALETAKSSGCQNILALRGDPPKGQLN
WESCENGFSYAIDLVKYIRKKYGDYFCIAVAGHPEGHIDNQDPEDDLKRLKEKVDAGADL
IVTQLFFDVDIFVRFVKRCRDIGIQCPILPGIFPIQSYSGLSRVISFNNNHVPQKIWDDL
SHIKDDDQAVKDYGIDLAVQFVHQIKKETGISGFHIYTFNLERSSRLLLEKLGLVPEQEN
VKPLPWNPSLGPNRTKETVRPIFWKNRKQSYIQRTESWDEFPNGRWGDARSPAFGEFDRW
GVSIKYPFEKQLAMWGEPESPDDIAVLFAKYCKGKLEGLPWSAQKLDPETDIIKQRLAAI
NLLGYLTINSQPAVNGARSNDPVYGWGPKHGYVYQKAYIEFFIPPNRLEELIKKIEHDPE
VTYFAVNKDGNLKTNTTSDEPNAVTWGIFPGKEIVQPTIVEPIAFMAWKDEAFGLWNEWA
RIYDRHSPSAETILNIYENWYLVNIVHNDFKDENGIWRLFDLEIDGDLSRRLRRGSGSL
>A0A837YQ24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus badius|TrEMBL
MKLLDRLQTEVLTADGAMGTLLYSYGIDFCYEELNVEKPEIIEKIHLDYIQAGADIIQTN
TYSANALKLARYGMENRTEELNKAAVRIAKQAAAPEQRFVLGTIGGIRGIRKSSASLSEI
KSAFQQQAEAILQESPDGLLLETYYDFEELTTVLQLLRKVTDLPIVSQVSMHEPGILQNR
LSLNEAFKQLESLGADIVGVNCRLGPYHTIQALEEVTLPEKAFLSAYPNAGLLDVEDGRV
VYESEADYFGQAAVQLRNEGVRLIGGCCGTTPKHIEAAKKALTGLAPITEKKVIAQKPIV
IKEPAPLVVPPLHEQVKKERTIIVELDTPKHLDTAAYIKGAKALQQTGMAAITMADNSLA
SPRVSNLAMGSLLKVQHHIRPLVHITCRDRNLIGLQSHLMGLHALGLHDVLAITGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGISFSGKPLKQKANFSVAAAFNPNVRILDRAVKR
LEKKIACGADYFITQPVFTKEKIVEIYEATKHLPTPIFLGIMPLTSSRNAEFLHHEVPGI
KLSEETLARMKAYEHDKEAAAREGVTIAKELIDTAAKLFNGIYIITPFMRYDMSIELIHY
IEELDGKTKERGIPHAETISN
>A0A6I5BYM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4926|TrEMBL
MASGTASTWTSEHPTVAEVLASGKRSYSFEFWAPKTPKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRTGTVRATQAIAENTTLVPVAHLTAVEHSVAELRHMIGQYADGGVRNILAVR
GDPPGDPLGDWVAREDGLTYAAELVRLIKESGNFCVGVAAFPDMHPRSENWDSDVRYFVD
KCRAGADYAITQMFFDPASYLRLRDRLSAAGCETPVIPEVMPVTSVRQLERLSRLSTAVF
PETVKERMLAAKDDPAAVRSLGIEFATEFCARLLAEDVPGLHFITLNNSTATLEIHENLG
LPHHRP
>A0A8H9HCH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces gaoshouyii|TrEMBL
MSSTPDDSAPAPHGPPTLSLELFPPRAGAAASQTWSALDRLLATAPDFVSVTYRPTFVLG
TRPAEPAVRVIREHNPAEDVVTHVLARSCTPLMAHLTCIGYRKRDVVEIVRLFLALGVRR
FLALRGDPPRGHDADELPGELAHAEDLVRVIREVEAEYFDDGERHLTIAVAAYPAVLDHG
RGVEILAAKQAAGADLAITQVFYDPEDYLSLARAATYCGVSMPLLPGILPMTDLARLSRL
ADLTGVPIPEGLAASLGPARGAQTVTRGIDATLRLATEVLDGGAPGIHLYTFNRTRPALD
VVSQLRLGGILGGERVSTSMQRDVRRAYLNATPGGDRRMPEPAHAGPARP
>A0A839S167|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella isguenensis|TrEMBL
MFSQPSAHHRVVLAGALRHASYEVLPFRSTEDKVLAHVPLDVPLTVTATEAKGIEATVEL
AVRLSKNGYHAAPHLPARLIRDRAELDDVAARLVESGIERIFAIGGDAAEPAGEFADAES
LLLALSEAGHSFRSVGIAGYPEGHGKLPDTVIDDALHAKAGRAHEIITQLCFNPDSTIGW
ARRLRAEGIHTPIRVGVPGSINRQKLIRVSAGLGLGQSARFLAKQSTMLWRFFLPSGYRP
DKLITALADQMGRPDNELAGFHLFTFNDLAGTERWRQQWLARLS
>A0A1Y3MPK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pseudomycoides|TrEMBL
MKILDLVSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADIIQTN
TYGANEAKLRMYGLENQVTQINKAAVKLAKAAVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEKVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQLALHEAGTTQNGN
DVNGILTQLLDYGANIVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGCYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPAHIEGMKRVIANVTPVTEKQIVQRQQVVH
IQTKRASTHVTLAEKARKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGSATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIEEIYEATKHLEKPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMDGHETQESAIEEGIRISQELINAAMKYFNGIYLITPFLKYEITENLVKYVK
EKQEVKEGIN
>A0A532C881|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPQRLIDVLNRGTFAVTVEYNPPKGTNISSILENAKQLVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMKLVQGLNNGKDMVGNKLDGSTAFTIGAAVTPEADLVGPVLAKFEVKV
KVGAQFFQTQAIYHPDVFAGFMKQVRPFNVKVLAGILLLRSAKMAEFMNANIPGMSVPSE
MIDELKAAGEKAEDVGVDIAVRTIKAVRPHCDGVHIMAIKATHRLAEIITKAELG
>A0A1V4S5J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4484_190.2|TrEMBL
MSEYKSGSNLEKVLKAGHFAFTGECGPPQGANVEHLKEKAAHLKGCVDAVNVTDNQTAVV
RMSSWAASLVLLQEGLEPNFQMVCRDRNRLAIQSDILGVYAHGIRNMLCLSGDHQRFGNH
PEAKNVFDIDSMQLIYTVKTMRDEGTFLNGQDIDVPPKLFIGAASNPFAEPFEFRVYRLA
KKIAAGADFIQTQCIYNMDRFREFMKRAVDMGLHEKCYILAGVTPMKSVGMARYMAKQVP
GMDVPASLIKRLQGAGKGKVAGEGIKFAIEQIEEFKEMEGVAGVHLMAIEWEHRVPEISE
LAGMLPRPKV
>A0A0E9ZJ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 10-1B|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKDELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQESADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A316KKK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fluviicola sp. XM-24bin1|TrEMBL
MKVTEHLKASDGTLFSFEILPPLKGKSIQSIFDGIDPLMEFNPRFVNVTYHREEFIYKER
ENGLLEKIAIRKRPGTVGICAAIMNKYQVDAVPHLICGGFSREETENALIDLQFLGIDNV
LALRGDSIKTESSFRPHQDGHSYAVELIEQIGEMNNGNYLMDDVNLEPTNFCIGAAGYPE
KHFEAMNLSTDLQYLKQKVDAGAEYIVTQMFFDNEKYFAFVDACRKEGITVPIIPGLKPI
KTMRHISFLPKFFHIDYPEALSAELLKCKNNKDAEQVGIEWGIQQSKELKAANVPCIHYY
TMSNSDSVKAIAKEIF
>A0A3N0WAN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. G0240|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIEN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINNLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHIEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITIPIIPGI
KPIATKKHLKILPQVFKIDLPEELISEVENAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKIAGELF
>A0A0K1XE43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiopseudomonas alkaliphila|TrEMBL
MNTTPRCSFEFFPTKTEVGHLKLMAAAEQLASRNPHFFSCTYGAGGSTRDRTIETVLGLK
QTTQVSTAPHLSCVGDTKAELKELLAFYQTQGIERIVALRGDLPSGMGMASSELRYANEL
IEFIRQETGEQFILEVAAYPEMHPQARNFEEDLQNFVRKVEAGANSAITQYFFNADCYFY
FVERVRKLGVEIPIIPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSQSIQAFG
TEVITSMCEQLLAGGAPSLHFYTLNQAEPSLAIWDNLNLSTKP
>A0A1V6CDG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division TA06 bacterium ADurb.Bin131|TrEMBL
MEKKSFSEKLKEGRFVITSEIGPPKGTNIEPHLKEADHIKEKVDAFNVTDLQSSVMRLGS
LATCRLLVENGFEPIFQITCRDRNRLALQSDLLSASVLGIKNILCLTGDHTTLGDHPDAK
PVFDLDAVSLLKVATDLMNGKDMKGNELDGKPEFFLGAVVSPGYDPVELQIIKMEKKIEA
GARFFQTQAVYDLKIFEKFMQKIQKYNIPILGGIVLLKTAGMAKYMNEKVAGVSVPDKYI
KMMADAKKEERPKVSIKIASELIKGMRGLCQGIHIMPLGWERYVPQVLEESGL
>A0A4Y3RFY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces gardneri|TrEMBL
MALGTASVRSDRARTVREILASGGTSYSFEFYAPRTAKGEQVLWNAMRRVEAVGPSFVSV
TYGAGGTTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNVLGQYADAGIRNMLALR
GDPAGDPLGEWVEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDKDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVAKAGCETPIIPEVMPVVNVKTLDRLPQLSNATF
PAHVKDRILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A8T8T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. AND4|TrEMBL
MSLPHVILTVLSTRDATGYDITKEFSASIGYFWKASHQQVYRELNKMAEKALVTCVLEPQ
EGKPDRKVYSITDAGRSALGEWFDQPTAHPTVRDEFSAKLVACAVQPAAPFRDQLSELVE
ESRKLVAHYKEIEAAYYATPSTLDKQARLERLTLRRNLMLREAWINWAEEVLTELEVIG
>A0A7S9D7K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium genosp. B|TrEMBL
MTDLTNPAPSDGQDGHFAVKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYG
AGGSTRERTHSTISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDP
PGGIGTPYSTHPDGYQTSDALVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKAKV
DAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRTGTSVPD
WLAEKFDGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISHLLGIR
AKSAQKAA
>A0A6I6E8U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermochromatium tepidum ATCC 43061|TrEMBL
MTTSATSKRVYSVELFPPKTVEGMDRLKQEVPKLNALGPAYFSVTYGAGGSTREGTFETV
AWLRTQGIDTAPHLACIGSTRAQIREILDHYHGQGIRRLVALRGDLPSGMGIGNSGEFRY
ANELVGFVRAEFGDAFWIEVAAYPEYHPQSGTPVRDLENFKRKVEAGADGAITQYFYNAD
AYFAFVESCERAGITIPIVPGIMPITNYAQLARFSDACGAEIPRWIRRRLESFGDDIESL
RAFGHEVVLRLCQRLLEGGAPGLHFYTMNQSGSVTRLWHDLGLSD
>A0A808W6E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia gladioli pv. gladioli|TrEMBL
MKPIELSLEFFPPKTAEGADKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLSAAPHLSCIGSSKDNLRAILDQYRSHGIRQIVALRGDLPSGMGEVGELRYACDLVRF
IRAEHGDWFHLEVAAYPEYHPQSRSPKQDLQHFADKVKAGANSAITQYFFNADAYFRFVD
DAARLGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGADV
ITAMCDRLIKQGVPGLHFYTLNLATPTRVVCERLGLSS
>A0A448K1T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella aerogenes|TrEMBL
MSYAKEMDTLNQHLVDLKGDINVSFEFFPPKNEKMENMLWESIHRLKTLEPKFVSVTYGA
NSGERGRTHCIVKRIQQETGIIAAPHLTGIDATPEELRVIAKDYWDSGIRRIVALRGDEP
PGYDKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDINSYLRFRDRCASIGIDAEIVPGILPVTNFKQLLKMAALTNVKIPSWLAKMYDGL
DDDQTTRNLVAASVAIDMVRVLSREGVNDFHFYTLNRSELTYAICHILGVRPNL
>A0A0S9K4X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia sp. Leaf264|TrEMBL
MAIDLPPTGGATRVPVSFELYPPRTDAAAIALGRTIDKLTEVDPAFISVTFGAGGSTRDR
SLTVLSYILENTDVEPMAHLTCVGSSAAEANGLVRRFLDAGITSFLALRGDPPLDGTPLS
VGDLQSASELVQLIHRVQQEREPFSQEAVRGTPGGTRLRARPRPERVAVAAFPNGHASSR
GPQQEIDALLAKQAAGANLAITQLFYRADDYLAFVDRARAGGVSIDILPGIMPAASAARL
RRIAELTEEEAPDELLIALEVEPTEEGRTEIATDFFSDLAAAVIAGGAPGLHLYTHNKHT
AVLDLLERIGHVPAALNRPIKENA
>W8R7Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces bottropensis|TrEMBL
MSALHEILASGNHSISFEFFPPKTEAGTRTLWKTIRRIEPLAPAFVSVTYGAGGSTRDRT
LEVSRRIAAETTLRPVVHLTAVGHSVEELRQVIGQYADAGVRDVLALRGDPPGDPNREWL
PHPKGFAYAWELVRLVRRSGAFSVGVAAFPEKHPRSPDWESDIRHFVAKCRAGADYAVTQ
MFFHVEDYLRLRDRVAAAGCPTPVIPGIMPATDVRQITRFAELSHAAFPVGLALRLEAAR
ADPADGHRIGVEYATTMADRLLAEGAPGLHYITLNRSTAALEIHKNIYNRLRSTHVLSAV
S
>A0A0V1BEV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella spiralis|TrEMBL
MNSSYNLQMKLKSPAYQRAVTDFGVYFEEDSFLSLMASLEAVELKATGHDLNSAAKKSTD
EIYRSLIDRIKENISSGRRFFSLEFFPPHTTEGLINLLKRVDIFANSQPLFVDVTWVMRS
DPASEKVTSSSSLADCILNFCLLDTMLHITSVQYNEKTVLFNLERAKKIGIRNILALRGD
ISDDANVTTTDFQYACQLVRFIRSHYGDYFTICVAGSYLLYAKVDAGADFIITQLFFDEM
HYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSKIVIPDSVLTTLESIKENAEAV
RNFGISFAVQLCRKLLNREHHVVPGLHFYTLNQEKSILEQIGFWKKAPVRMFPWKKHTVH
SVRCREAVRPIYWTARPKSYLCRTRDWKQFPHSRWGDVGNPAFGNLKHYLFSCIDQMDDS
CALDMWDKELSTLEHVRDIFCNFIARTPNRHGHSVRRLPWNENHLDPAADILKNELIYYN
SNGILTINCQAAVNGLPSSDPIFGWGEANGYIYQKVDARCILISLGYLEFFASSTCTTIL
LNHVQNFPSINYHAINFDGSFETFNYDEDATVALTWGVFVGQEIVQPTVANAASFRVWKD
EAFDLWQRWAGLYESGSIGRKLLQKIHDDYRLITLIDNDYPQPCSLSALLRAVISDYWGK
KLDDG
>A0A1H8IEZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AR20|TrEMBL
MRVIDLIHNSEKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLFWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEVLKCKNDKEAELVGIEWCAAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A318M840|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium indicum|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLIPDFISVTYGTGKQSDRTATARIARTIH
TEYGIPSVAHLTAQYADKEIVDQALDMFDRAGVAAVLPLRGDSVEGRTPAGVFDHASDLV
AYIHAKRPDMTIFGACYPETHPEAASPQADLDNLKIKVDAGATHLISQLFYDNDYFTDFL
GRARGTGINVPIEAGIMPITNAGQVRHMSEVCAASIPPAVDTILDRWGDDRTSLREAGII
YASQQIADLVSQGVDGIHLYSMNQAGVTRRIWHNVRHLFKVRQASSSMLSL
>A0A7Z8YCH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga ochracea|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKVVESCKNNNEVKQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A7Z0TLA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. UH6|TrEMBL
MALGTASTRTDRARTVRDMLASGRQTVSFEFSAPKTEKGERNLWNALRRVEAVTPDFVSV
TYGAGGSTRAGTVKETEQIVSDTTLTPVAHLTAVDHSVSELRNIIGQYADAGIRNMLALR
GDPPGDPMGEWIAHPKGLHYAAELVELIKESGDFCVGVAAFPELHPRSPDWETEIRHFTD
KCRAGADYAITQMFFQPESYLRFRDKAAAAGCETPIIPEVLPVTSVRMLERLPTLSNAVI
PARLKERILTAKDDPATVRSLGIDFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHPVQGWTGSV
>A0A6I1MJ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium tarantellae|TrEMBL
MNIREIFEQKDVVFSFEVFPPKKSSSIDVIYKTLEELKELKPDFISVTYGAGGTSAENRT
LELASLIKNKYNIEPMTHLTCIGSKKEEIRKVLQALNENGIKNILALRGDIDESNIIKGD
FNYANELIEFIKKFGNFNVSAACYPEGHLECESLSRDLLNLKEKVDAGATHLISQLFFDN
DLFYNFLDKSESKNIRNIPIQAGIMPVVNKKQIERIISLCGASFPKKFMKIVEKYEHDKD
ALRDAGIAYAIEQIIDLVSNDVDGIHLYTMNNPYVAKRICSNIGSIVNSINNKKNV
>A0A2N1VK80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium HGW-Ignavibacteriae-1|TrEMBL
MLDRETILERIRNGVLLFDGGFGTELYNRGVFINRCYDEVNLTNPTLVKQIHEDYKRAGA
DVIQTNTFGANRYKLAKFQLADKLYTINFEGARLARAVAEDDINVAGSIGPLGIKIEPLG
PTSREEAKLAFTEQIEALLAGGVDMLIFETFIYPEELQIATEAAREICDLPIIAEMTIDE
DGTSLTGAEPEFIIKQMELLKADAIGVNSTVGPQVMLKWLETVRPLTKMPLSVMPSAGKP
KNIDGRNLYLTSPEYMGEYAKHFIQAGANVIGGCVGTGPEHIKRMRNMLNAIKPEISKRK
FEFLEIKRPDDVVIIESPDKSRFARRLSAGHFVTSVELLPPHGLGSKAVIDKARELFYHG
IDCINIPDGPRASARMSAMSLAVQIQNIVGIETILHYVCRDRNVIGIQSDLLGSYALGLK
NILAITGDPPKLGNYPDATAVFDVDSIGLVNIINRLNHGLDIAGNPIGEPTGYFCGVGAN
PGAVNLDEELARLDWKINAGAEYIITQPVFDLNVFENFLNRIQHVDIPVIAGLWPLTSIR
NAEFMNNEIPGCDVPDKILGRLRKHQDSKEDSLKEGIEIARETLEIMKEYIAGVQISAPF
GRVQSVINVLDGIQLY
>A0A7L1QPY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cisticola juncidis|TrEMBL
MVNETQQPCSASSSSRSDGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWREDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7J3D856|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomicrobia archaeon|TrEMBL
MKAGSNLEKVLEAGHFAVTAEIGPPKSANPEIVRHHARMLKGYADAFNLTDNQTAIVRLS
SLASAVICLQEGVEPVMQMTCRDRNRIALQSDLLGASALGIRNVLCLTGDHQTFGNEKGA
KNVYDIDSIQELLIFKKMRDEKKICGGEDLEEAPKVFLGAAENPFADPFEFRVTRLAKKA
NAGADFIQTQAIYDMERFEKWMEGVRERGLDKKVHILAGVIPLKSVGAARYMKNKVSGMI
VPDSIIDRMKKAKDPKAEGIKICVEQIEYLKTVKGVHGVHIMAIAWEEIVPEIVRQAGLY
PRPSV
>A0A7Y8VTN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 903|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYQNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
IMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVESCKNNNEVKQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A6B3A2Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7909|TrEMBL
MALGTPSTRTDHARTVREMLATGATSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVKATQDIAAESTLTPVAHLTAVDHSIAELRNMVGQFADAGIRNILALR
GDPPGDPMGPWVDHPQGVKYAADLVRLIKEAGDFCVGVAAFPERHPRSDDWDTDIRHFVD
KCRAGADYAITQMFFDPEAYLRMRDRVVAAGCETPIIPEVMPVTSVRQLERFPQLSNATL
PDELKDAILAAKDDPAAVRSIGIDFATRFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A4W3HD56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callorhinchus milii|TrEMBL
MERNCSDSSSRESSRSSTPSLESDRLREKMRRRIESGDKWFSLEFFPPRTASGAVNLLSR
FDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETLLHITCCNQSKEQIT
EHLQKACRLGLKNVLALRGDPIADKWQTEEGGFNYASDLVKHIRNKFDDYFDICVAGYPT
GHPECTSYEEDLKHLKEKVEAGSDFIITQLFFKPQTFLKFLKDCRAIGITCPILPGIFPI
QGYHSLRQLVKLSKLQVPQEIKDIIEPIKDNDAAIRNCGIDLATDLCKALLTSGAVPGLH
FYTLNREVAATEILRRLGLWIEDPRRPLPWAVSANPKRKVEDVRPIFWASRPKSYIYRTQ
DWDEFPNGRWGNSSSPAFGELNDYYLFYLKSNCAKEELLKMWGEELVNEEHVFEVFTAYI
TGESNRNGTKVTCLPWNDESLAVETNLMKAELQKVNRRGILTINSQPNINAKSSTDPVVG
WGPEGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVKSENINNASDLQPNAV
TWGIFPGREIIQPTVVDPISFMYWKDEAFALWIERWAKLYPEESPSRQIIQNIHDNYYLV
NLVDNDFPLKNCLWQVIEDMFLLKSIEKPCDDAAAVDDLAAVP
>J3LU35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryza brachyantha|TrEMBL
MKVIEKIREAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVENIDEALTTIKSNGIQNVLALRGDPPHGQDK
FVQVSGGFACALDLVRHIKAKYGDYFGITVAGYPEAHPEVIHSAEGATLEAYSNDLAYLK
QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKVLASGIKTLHLYTLNMEKSALGILQNL
GLIEESKVARSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPLKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINLKGFLTINSQPSVNGERSDSPSVGWGGPGGYVYQKAYVEFFCSKDKLD
QLIEKSKAFPSLTYIAVDKNGESFSNIPTNAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWSKGWACLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAFKEI
>A0A6I7PS74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradymonadales bacterium|TrEMBL
MKVVEHIERAKGPLFSYEIVPPPRGRTVQDVIEAVEALAPFNPPWIDVTSHAAGAYYQEN
PDGSVERRIYKKRPGTIGICGIIQNRFKIDTVAHILCLGFTKEETEDALIELNYLGVENI
LAIRGDGPNYKKVISNGRSVNVYAADLVSQVVDIKKGRYVSDITGAHPIDFCVGVAGYPE
KHFEAPNLKLDLHYLKEKVDRGAEYIVTQMFFDNQKYFDFEKACREHGIKVPIIPGLKVL
RSEKQLTTLPKNFYIDLPTALVDEISSSPEHASEIGVRWAKKQCVELLERGCRNLHFYVM
NDASLVKDVIKSLS
>A0A7X5UNC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora amisosensis|TrEMBL
MTSVIERLQSRAAGFSVEFFPPRDAADEAVLWRSIRELEPLDPAYVSITYGAGGSSRQGT
IRSIARVATETTLVPMAHLTAVNHSVAELRHVIGSYAAVGVRNILALRGDPPGDPYGEWV
PHPHGLRYAEELVTLVRSLGDFCVGVSAFPYGHPRSPDLATDTAHLVRKFAAGADFAIAQ
LFFEAEDFLRLRDRVCAAGCDKPIIPGIMPLTTPRTLAKTIELSAAEPPRWLVDRLRPLS
DDPKSFRAAGLDVVTELCERLLAEGVPVLHFYTFNRSKATRELVNRLGLVRVGA
>A0A3B4DAS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pygocentrus nattereri|TrEMBL
MVNQRLDTGWQACKSDSSGGSNSGESSKESSRCSTPVLDADRTDRLRDKMRRRIESGDRW
FSLEFFPPRTAGGAVNLIARFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAINY
CGLESILHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGADWEEEEGGFNYATDLV
KHIRHEFDDYFDICVAGYPTGHPEAESYEEDLKHLKEKVDAGAHFIVTQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDDAIRNYGI
HHAVEMCKVLLASGDVPGLHIYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLK
MWGEELTREESVYEVFTNYITSQVNQSGHKVRCLPWNDDPLAPETNMLKEKLEKVNRRGV
LTINSQPNINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVSALLKVLKKYEPRVNYH
IVNVQGKNITNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWGKLY
EEESPSRMIIQYIHDNYFLVNLVDNDFPLNNCLWQVIDDMFELLDAPPEPLE
>A0A8I0BN74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga sp|TrEMBL
MRKSLETGKCVVLEVLTPRGTNLDKFMEFTEEAWKTGIDAFTVTDMPMGRVRMAPWAASH
LLVESGKDVLMHFTRNTRNMIRIQSDLLGCHALGVKNLLLLSGDNPSHGDYPETTSVNDI
DILDLIRLTKLMNEGTDLAGNKIYGKTDFFVGGALNPFSDEDVERAKQKIEAGVDFLVTQ
PLFNSEVAKKIKEELNTKILASIVFFENAKQMSYFSNVPGIEIPDEIVNSAEKGDDYLKE
KSFESVLRFVEETKDVLDGFYIVAIVKDLEKIRKVVEIAKS
>A0A172Y470|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas naejangsanensis|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRNAVNVSFEFFPPKTDAAEANLWSAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIEGYKAIGVDH
IVALRGDPPGSAGIGGAYTPRADGYANATELTAALGRIGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVTNFAGLQRMT
AACGAALPDWLAGHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAVA
>G5QB50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Montevideo str. S5-403|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>V7EKE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter sp. CACIA14H1|TrEMBL
MTTPRISFEFFPPQTLDASFRLWETVQMLAPLKPSFVSVTYGAGGTTRKLTHEAVGAIGR
NYGLNVAAHLTCVDATKAETLEIAEGYAAAGVTEIVALRGDAPKGAERFVPHPEGFASSV
ELVEALAKTGKFKIRVGAYPEPHPDAGFAGADVEHLKRKVDAGATSAITQFFFNADTFFR
FRDACVKAGVDVPIIPGILPIISWEGAKKFAARCGAQVPAALDEGFRVAARDGREDLLAL
TQCTTLCARLIEGGVEDLHFYTLNRPHLTQAVVRALGITPEVALEKVA
>A0A0K1S436|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis panniformis FACHB-1757|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>A0A101GDG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atribacteria bacterium 34_128|TrEMBL
MNLREKLAANKFVVTVELDPPKTLNLERILTEVNSTNFRKLVDAVNVTDCPLAKLRMSPI
ALSHIIQERIGLEAIFHITCRDRNLLGLQAELLGASALGVKNILALTGDLPEMGDYTRAT
GVFDVDSIGLVKMVNKLNNGYEYSGNELKDKTDFFIGIAVNPTAQDLKKEIARFEEKLSA
GTNFVQTQPIYDIGLLERFLKLTAHINIPKIIGIMPLKSYKMVEYLNKNLPGIFVPPEVK
ERMRGKDVEEGVKISRELISKIRKFKEVTGIHIFPLRDMDLVCRLLS
>A0A4V4H6F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Musa balbisiana|TrEMBL
MKVIDKIRGATEGDGRTVFSFEFFPPKTEDGVENLFERMDRMVAHSPAFCDITWGAGGST
ADLTLDIANRMQNMICVETMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQD
KFVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDMIQEDGGATLEAYNSDLAYL
KRKVDAGADLIITQLFYDTDNFLKFVNDCCQIGINCPIVPGIMPINNYKGFLRMTGFCKT
KIPSEITAALEPIKDNEEAVRAYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKVSRSLPWRRPANIFRVKEDVRPIFWANRPKSYISRTVGWDQYPHGRWGDSNN
PSYGALTDYQFMRPRSRDKKFQEEWATPLKSAADINERFMKFCLGKLRSSPWSELDGLQP
ETKIIDEQLSQVNLKGFLTINSQPAVNGEKSDSSAVGLVLNLMFFHFAGWGGPGGYVYQK
AYLEFFCSKDKLNLIIEKCKTLPSLTYIAVNKEGDCVSNVAPNAVNAVTWGIFPGKEIIQ
PTVVDPASFMIWKDEAFEIWSRGWARLFPEGDPSRELLEQAQRSYYLVSLVDNDYIHGDI
FAAFKDT
>A0A7Z7MYG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. hl-4|TrEMBL
MSRHEHPLGISFEFFPPNTDAGRDKLIRTRDELAARKPRFFSVTYGAGGSTQARTREIVR
KVGQSGITTAPHLSCIGSEKAQLRDLLVQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRDETGDHFDIAVAAYPESHPQALNLDRDVENFARKMKAGANMAITQYFFTADAYF
HFVEKARAAGVDQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKIVDNLSG
>A0A7J6PUL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perkinsus olseni|TrEMBL
MARLIDKIQNRWDHDRDNGESTRVPFFSFEYFPPKTDMGVQNLYERLDRMAELGPMWIDV
TWGAGGSTSGKTFEICRNALTYHGLDVMMHLTCTDQPVKEIDEVGIRNILALRGDAPMHS
GEWEACQGGFSHAVDLVRHIRGTYGDYFCIAVAGYPEGHLEAESMEEDLAHLKEKVDAGA
DLIITQLFYDTEVFFNFVAAVRALGIQVPIFPGIMPIQSYSGFKKMTEFCKTKVPRAIAD
QLEQVKGDDQKVKDLGVEICVAMCSQIMSYGVDHFHSSGGLHFYTLNLESSVSRIIERLM
MVDSHVATRALPWRPSKASSRQEENVRPIFWSNRQKSFIQRTSCWDEFPNGRLGNQASAA
YGDFELNFRSYSKETQDKVAADRRRMWGDHVPNGDHVRRVFTAFIKGEVKRLPWCTESPT
EETLFIQKQLMRLNQCNMLTINSQPRVNGALSTDPYVGWGPGGGFVYQKAYVEFFCPESQ
LEQLIRVRRCSTCAHG
>A0A7X8F7L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MNVIEKIQSTGGKTAFSFELLPPLKGNSLDGVYYTIDTLREFDPKYINITTHRSELVYRK
KPDGSSELIAHRNRPGTVAIAAAIQHKYNIPVVPHIICSGFTKEETEYALIDLQILGINN
LLLLRGDKGKHEEVYTPVGHRYATDLQGQVNRFNQGFFLDGTEMNVAMQPFSYGMACYPE
KHSEAPDLESDLKYAKMKVDAGADYLVTQMFFDNQKYYDFVEKCREAGIHVPIIPGIKPI
TLMSQLTVLPKIFHTHIPDELAEALRVCKTDEEAVEVGVEWCIRQAKDLIAHGVPSIHFY
SLMATESVKRVAQAAY
>A0A7X9CIT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKISELFDKTQQTAFSFELLPPLKGNSIGQVFNTIDRLKEFDPKFINITTHHSENIYRED
ESGVYRKTNVRKRPGSVAIAAAIQHRYGIRAVPHIISKGFSKEETEYALIDLSFLGVTDL
LLLRGDTKKLDPQQRSMDSHDHATGLQEQVNNFNRGIAFDGSTFTPPETSFSYGMACYPE
KHEESPNMESEINYTKMKADNGADYLVTQMFFDNSKYFAFVDRCRAAGITIPIIPGIKPV
HLLSQLTVLPQIFRSEIPEPLEKELRKCKNDEEAKEVGVEWCIAQCRELVAHKVPSIHFY
SLMATESVRRVAKEIY
>A0A7C6BX71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSLIDKIKSAKKTAFSFELLPPLKGNGISGVYKTIDTLLEFDPKYINITTHRSEKIYKEN
EQGLYEQVSVRNRPGTVAVAAAIKNKYNITVVPHIICSGFTKEETEYVLIDLKFLDINDI
LLLRGDKAKHESTFVPTGHEHATELQKQVNRFNEGYFLDGSEMKIKEKPFSYGMACYPEK
HEEAPNMESDLYWAKKKVENGAEYLVTQMFFDNQKYFDFVKKCREIGIDVPIIPGLKPIT
FMNQLTVLPKIFKSDIPEDFARELRKCKTDDEAKEVGVEWCTQQAKELIANNVPSIHFYT
LMATESVKRVAQEVY
>A0A7C6HZN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVSELVNAAKKTAFSFELLPPLKGNSIQQVFNAIDRLKEFDPKYINITTHHSENVYQED
ETGGYRKVNVRRRPGTVAIAATIQYRYGIRAIPHIISRGFSKEETEYALIDLSFLGLTDL
LLLRGDAKNLDAEQRAMDSHMYATGLQEQVNNFNEGIGYDGASFTAPEVPFSYGMACYPE
KHEESPNMESEIYYTKMKVDNGADYLVTQMFFDNRKYFEFVERCREAGITVPIIPGIKPI
HLMNQLTVLPRIFRTDIPEELASELRKCKDDEAAKEVGVEWCIKQCKELVQSGVPSIHFY
ALMATESVYRVAKEIY
>A0A6L8QB23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium|TrEMBL
MKISEKLRLSEPNFSFEFFPPKDSEGFASLFETIARLKVSDPGFVSVTYGAGGSTRSETV
DLVGNIKNFIGLESMAHLTCVGHDQQEIRSVLESLQSRNIDNILALRGDPPQGEETFLKT
EGGFEYGNELVAFIKKNFSFCVGAACYPEGHVECKDLDKDIENLKKKVDSGADFLVTQLF
FDNKHYFDFMDRAAKANINIPVIPGIMPVLNLKQIKRFTKMCGATLSPGLINKFSGIEDD
SEKVRQIGIAHAIEQCRELLENKAPGIHFYTLNRSKATLTILGALREFT
>A0A1Y0CIH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sutcliffiella horikoshii|TrEMBL
MGILDSLQQDKILIADGAMGTLLYSYGSDCCFEELNLSQPNQIYNIHKAYLNAGANLIQT
NTYAANYHKLERYGLQDQVKEINSAAVRLAKRAVADHPDAHVVGTIGGIRAIKPEAIPLE
EIKRTFREQLYCLLLEGVDGILLETFYDLEELETVLQIARKETDLPIIAQVSLQEVGYLQ
NRVHITDALNRLESLGADIVGLNCRLGPYHMISTLEEVSIPKTAYLSAYPNASLPSYVDG
KLEYDSDADYFKETALAFRDQGVRLIGGCCGTTPAHIKAFSDALEGVAPLKEKQVKRKER
TIILPSSKKKDVPTPLFEKAKKQQSIIVELDPPRKLNTDKFMAGAKALKDAGIDALTLAD
NSLASPRVCNTALGSIVKSDIGLRPLIHITCRDRNLIGLQSHLMGLHQLGIHDVLAVTGD
PTKVGDFPGASSVYDVTSFGLINMIKQFNQGVSLSGKELGERTSFSVGAAFNPNVRIIDK
AVERLEKKIDAGADYFISQPVFSEEKLLEVYQATKHIEAPIYIGIMPLTSSRNANFLHHE
VPGIKLTPQVLEVMNRHQDDPQQASLEGLNIAKGLLDAALELFNGIYLITPFMRYELTVE
LANYAKKYGPFHSSRRVQNV
>A0A832R273|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MRISELINKGGKTAFSFELLPPLKGNSINKLFKAIDRLKEFDPKYINITTHHSENVYKEG
SDGVFRKVNVRKRPGSVAIAAAIQNKYGIKAIPHIISQGFTKEETEYALIDLSFLGVTDL
LLLRGDTKNLDPQQRSMDSHKYATELQMQVNNFNLGKGLDDSVFTPSEVPFSYGMACYPE
KHEESPNMESEIFYTKMKVDNGADYLVTQMFFDNSRYFEFVERCRAAGIKVPIIPGIKPI
HRKNQLTVLPRVFRTDIPEELEKELRKCDNDDDAKEVGVEWCIKQCKELVDAGVPSVHFY
SMNAVDSVRRVAQQIY
>A0A8F8BFD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter hormaechei subsp. steigerwaltii|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMFAADLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A2J6WJN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditerrivibrio nitroreducens|TrEMBL
MKICDKLNIKKRVLSFEFFPPKKVENEHILFETLDELTNFNPDFVSITYGAGGSTKDKTL
EWTLKIKNDYKLTVMMHLTCITSDKEEIDELLDNLKKNGIENILALRGDIPKDGLNYHIS
NDFKYASDLVSFIKQKDFCIGVAGYPEGHLEANSIEEDILNLKKKIEAGGDFIITQLFFD
NRLFYKYLELLAKNDINTHVLAGIMPITSFAQVDKFKKMCGVYIPEEFINRITDKDDDYV
FNAGLEYTIKQCEDLLSNGVKGLHFYTLNRSEATKKILNNLKYEV
>A0A1A2DHA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. 852014-52450_SCH5900713|TrEMBL
MSAGLECPKRMEFGPCGGVRPDGQCEMRPGACAFDGVVAWSGRQHAARPARAPLVLTDFS
CTPFDRQDVAATAAVLAPGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSINVETVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASTGMVAAAP
ETPTAPPVADRPARLVQKQRAGASLAVLNHVPRPEMVADFVRAARAAGLAIPVIAAVAVF
TDAVSAAVLQGLPGLELDRAVTEQVLGAPDPVSAGIEAAVAAARALLSIEGVEGVNVSGL
ASAAGGRIGAEIKAEVGRRIRVEGRR
>A0A1V5N187|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin416|TrEMBL
MSVINNILNNQKTAFSFELLPPLKGNSINSVFKTIDTLKEFDPKYINITTHRSELVFKPL
SNGLYQQVAERHRPGTVAVAAAILNKYGIPVVPHVLCSGFTEAETEYVLIDLQFLGITDL
LLLRGDKARHEKAFIPTGHAHATDLQQQVNRFNEGFFMDGTPIKQQGQPFSYGMACYPEK
HEEAPNMATDIHWAKVKVENGASYLVTQMFFDNQKYLTFVEACRNEGITVPIIPGLKPIV
LLNQLTVLPKIFHVDLPEDLTKALSECKTDADAATVGVEWCTQQANELKAMGVPSIHFYS
MMATESVRKVASAIY
>V4R5X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibaculum baratangense AMV1|TrEMBL
MTQQDPKPLAPDFSVSFEFFPPKNEAMERTLWRSIERLAPLQPKFVSVTYGAGGSTRERT
HNVVARIVRETPLRPAAHLTCVGASCDEVDEVVRLYHEAGVRHIVALRGDPAEGVGACYA
PHAQGYQTTADLVAGIKRVGDFEVSVSAYPEKHPESPDVDADLDVLEAKVDAGADRAITQ
FFFSNEHFYRYRDRVAARGIDVDLVPGILPISNFAQVKKFAGMCGASVPDFLGERFEGLD
EDPETRQLVAAGVVAEQILDLAANGVKEFHFYTLNKAELSYAACHMLGLRPHFATDAAA
>A0A6P1VZ25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma endbachense|TrEMBL
MFLEKIKSGESGVLLYGITPPKAGTTPERIAEIAQKTMERLSTLDIDALVVYDVQDESAR
TTEKRPFPFLNALDPLVFAADYLSTLNIPKIIYRPAGKFSNVELSAWLEELHGYNFYPVF
VGVPAPDFPVKTSLPEAYKIWSKHQDTSVIGAVTIPERHKVLKDEDVRMLDKMNCGVSYF
ISQCVFNLDYAKQVIEDLAISCNREHIKSPTIIFTITACGSTKTLHFMEWLGIHVPDELK
EDLKKSDDILEKSVKICLDIASELTTYCMERSIPFGFNIESVAIRKAEIEASIYLANEIG
QMLHHKGVRKSSESKDYEVTNGYR
>A0A6N7X8Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olsenella porci|TrEMBL
MRPRGEPTVLIRDILSSKQSFSFEIFPPKGEMSVDQAADVASQLCENHPDWISVTFSAGG
SGNSQNTVSIARRIEESGKTTALAHLTCMGATKADVDRYVEEFRSAGVHNVLALRGDRVP
GREPIDFEHASDLIAYLRDKGFCLGGACYPEGHLESDSLRQDIENLKRKQNSGVDFLVTQ
LFFTNEDFYRFRDECSRARVKVPIVCGIMPFTSVKQIQRMAFNCGASIPVSVIRRLARAG
EDPAAQRQAGLEYACEQICDLAANGVDGIHIYSMNKPEVGRATHDALASCGYLRG
>A0A7L4HDK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Podargus strigoides|TrEMBL
MVNETQHTCSASSSSKSDCGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVEGFNYAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAENYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A2V3AD94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus oceanisediminis|TrEMBL
MNFLDKLKNEIIIADGAMGTLLYSYGTDSCFEELNLSQSEQIQHIHEAYINAGAGLVQTN
TYAANYLKLQRYGLEDSVKEINSAAARIAKKASNGKAYVAGTIGGNRGIKPNMVSLEEIK
RSFREQLYCLLLEGVDSILLETYYDLEELETVLAIARKETDLPIIAQVSLQEAGVLQDQT
PIADAFSRLEGIGADVVGLNCRLGPHHMLKTLECVPLPKHAFLSSYPNASIPAYTDGKFH
YEGDADYFRQSARDFHNQGVRLLGGCCGTTPAHIKAFADELKGIAPLEEKEVKAKKEIIV
SEKPSPSRDLPPLQEIVKERPSVIVELDPPRKLDTTRFFEGAKALKEAGIDSITLADNSL
ASPRVCNSALGYLVKQQTGLRPLVHVTCRDRNIIGLQSHLMGLHALGLNDILAVTGDPAR
VGDFPGASSVYDVSSFELISMIKQLNEGLSVSGKDLGQKAAFSVAGAFNPNVRSLEKAVG
RLEKKIDHGADYFISQPVFSEEKLLEIHEAVKHLKAPVYIGLMPLTGSRNAEFLHNEVPG
IKIADSIRDRMAALKDDPVQAGREGIAIAKSLIDAAAELFNGIYLITPFMRYEMTVELSN
YAREKTERLSRRKQHA
>A0A1G0ZMI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium RIFOXYA12_FULL_48_11|TrEMBL
MENRFQESLTKSGRMSITWELIPGRGAREKLLDNALLAAERVAKDGRIDAVTLTDNPGGN
PAMLADYLGQEIMRLGVEPLVHFTCKDRNRNQIESQLYALDRVGVRNLLVMTGDYPVSGF
LGRPAPVFDLDPINILKLITEMNDGLSYPGPKGVIRHNPSHFFAGAAVSPFKSTEAELMV
QYLKLKKKIKAGAQFVVTQLGYDVRKFHELMMFMKQNNFNIPVVGNIYILTYGAAKQMNE
NKIPGCVVTDRLLAEYEREKSLPDKGVEARLLRAAKMYAFMKGMGFKGVHIGGHGVKYDQ
VLQVVEKGEELSSRWQDFIPEFDYAQPGGLYLFKKDEKTGLNQEVLEEVKDRPLDAPVGV
IYRMSRVVHRLLFEPDSSLFGLMQKICRKLDGSAGEKVFHKLEHLAKVMLYDCHDCGDCA
LLDVAYSCPMSQCPKHQRNGACGGSRDGWCEVYPGERKCIYVKAYARLKNYHETKVLDGE
IIPPCNWDFYQTSSWMNFYLGRDHSAERFGITKPVEQKQVRRQEQPQLAM
>A0A1V5RQC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium ADurb.Bin325|TrEMBL
MIHPFLARLRRGPLLADGAMGTLLHARGAAFEQCVEELNLAQPDWVREIHLAYIKAGAEV
IQTNTFAANRIKLAECNLGDKTRDINFRGVKLAREAREISGAAAWIAGSVGPLGKRARRN
GVLQHAAAAEAFREQIHVLWEAGADLLILETFSDLGELLLAAETARAATDLPVVAEITFG
NDGLTFEGAGPAEVAQRLAQAGVDVAGVNCSLGPARILEFIAQMRAAEPALLLSAMPNAG
LPFHSGGRMAYPTAAPYFAERVPQFLAAGATLLGGCCGTTPAHIAAMRGALDRVADRGLQ
PADRRAVAELSPLPMVRVQPVESAALLALEAEDAEAGPAPTGLLRKLREGRFVVSVEVDP
PRGFSAAKMIEGARIAQQHGADAVNVADSPMARVRMGALALCVLIQQQVGIETILHFTAR
DRSLTGLQADLIGAHALGIRNIIALTGDPPSLGDQPDSTPVYDVDSVGLVHIIDGFNRGL
DRAGKPFGSRSAFTIAVACDPTRPDLAQEVDRFHKKVSEGAHLTMTQPIFDPAVWQRFYD
LYEQRHGPFPVPVLIGILPLQSHRHAAFLHNEVPGITLSEDALARMARAGADGRREGVKM
AQELLLELMARPKVQGVYLMPSFGRYEVACEVLEVVQRGAD
>A0A286UKQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrrhoderma noxium|TrEMBL
MRISDKIAQADKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPKEKVDIALREAKQHGCRNILALRGDPPMGKDT
WEATEGGFVHGIDLIKHIHKHYDDYFDIAVAGFPQHMLLPPEEIEFEMKCLKEKIDAGVS
FIFTQMFYDVDIFISWVHAVRAAGITIPIIPGIAPVQTWNGFMRATSLAKTIIPKHFMEA
LEPHKNDDEQVRAIGVKLVADMCRKILAEDLGIRGLHFYTMNLEKATKMLLEELNLVPRV
ETIKPLPWRQSLTPTRRQETIRPIFWANRTKSYIARTENWDEYPNGRFGDSRSPAFGELD
GYGVWLKQTKEEALKIWGSPTTFAEIAELFSRFCQSDLSSLPWSDESPSAETGVISEQLA
KMNKFGFLTINSQPAVNGASSDDKIHGWGPGNGYVYQKAYLEFFVLPELLETLLPYIERD
SQLTYYVINKRGDLRTNTKSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAYELGRQ
WARLYEPESPTHKLITEFMESAYLVNVVHNDFKDPEAIFKPFFLAGEAYNARKNKDSGVV
ANGIH
>A0A515ETH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax sediminis|TrEMBL
MSATSQLPLSLEFFPPKTPEGAEKLKQVRQQLYVLAPEFCSVTFGAGGSTQEGTFAAVRD
ILAEGVSAASHFSCIGATRETVRAQLTILKAMGVKRLVALRGDLPSGYGAGGEFHYASDL
VAFIRTETGDDFHIEVAAYPEVHPQAKSPASDLQAFANKVNAGANSAITQYFYNADAYFR
FVEEVDALGLNVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDDVVSIKAFG
LDVVTDLCEQLRAGGAPSLHFYTMNQSASVLALCQRLGLHSKA
>A0A3B7QHU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WCHAc010034|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSITYGAGGSTRERTLAAIADFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFI
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDTASIKAFGHE
VIAKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A291H219|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium ginsengisoli|TrEMBL
MTSQTGPAAAEGAPQFEVIPLPGIVDQVAQMLPAGSRVTVTASPAQGLDATLEAACALAR
CGFTAIPHLAARMLHDGGEVGEHLARLTEAGIAEVFVIAGDAPHPAGSLHGALDLLEVLA
EASPGLVLGAGTHPEGHPFVDEAESLRLLREKARYVSYLVTQMCFEAEPLLTWRERLHVA
GIGLPLRPGLAAGVGTARLLSIGPRIGVGRSLRMLSAEGSGVRRLLAPGRWDPAPLLEEL
RVETRTTPGPALLGPHLYTFNDLRAARDALR
>A0A1E4G3G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterium sp. SCN 64-44|TrEMBL
MKPVLGAYALEITGKAIAEVDLAKSHIPPHTPINVAFLGNESHEQRINAASVIRSCGFEP
VPIISSRRLRSELDRDRLLGALVTEASPERFIFVGGDPSEPAGPFLDSIALLKSGVLERH
SIRHVGIVAYPEGHPKIDDEALWNSLRWKIRFLSEAGCSIEITTQFGFDTAAVVRWIKQL
RDEGIEAPVRIGVPGPSDTGKLLRFAKQFGVVTSVALARRYGLSLTNLARKAVADRYWTD
LSENLAGQQFGDVRFHLYPFGGMLEGVRWMNDRLEAASGTGRGD
>A0A519VSA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKIIDHINNAKGKTLFSFELLPPIKGQSIQGIYDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMHKYKVDAVPHLICGGFTKDETENALIDMQFLGIDN
VLVLRGDARKSDNAFIPTPDGHAFASDLLGQVADMNKGKYLHDDMGTSERTDFCVGVAGY
PEKHFESPNLDTDFRYLKMKVDMGAE
>G7TDS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzicola (strain BLS256)|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLNYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
AALCERLMAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1F9QXT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula sp. RIFOXYB2_FULL_45_6|TrEMBL
GAYSLGINTMLCLSGDHPKFGDHATAKSVYDLDSVQLVRMVQKMRDEGKFQGGADIDCPP
KMFVGAASNPFAEPFDLRVSRLAKKIKAGADFVQTQCIFNLDKFEKFMEMVCDRGLNEKV
YLLAGITPMKSAGMAKYMKNKVPGMDVPDEVIKRLEGVSKAEQPEEGIKIAVESIQRLKE
VKGVHGFHIMAIEWEEKVPQIVEKAGLFPRPAVENL
>G7TM72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzicola (strain BLS256)|TrEMBL
MISIDMPSHTRAITDAYSLEVSVKDIGALTKAAPRLLPGSSMFIPYLPGQHDAARLAAAQ
LVRSLGFEPMPHLSARRIGAPEELQAFVARLVDEAGVTRCFVIAGDPSTPKGPFADSLSL
IETGVFERSGIRTIGVAGHPEGHPIMRTAEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
MVVTWVEALRARGIPHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLASRLTDAHGDIRLHVFPFGGIAQSVAWVAQYRSRASSQDRMSSVRADQA
>A0A1F5VGF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Giovannonibacteria bacterium RIFCSPHIGHO2_01_FULL_45_23|TrEMBL
MRSGEFLVSIQIDPPGVSTDLKEFQTTIKKLIEVGAALFDINSSRRISHDSVELAVALAR
RKIDVIPHVTTRDSSINGLLNQAFAAYSLSKVSAFLIITGDPYEAEKAIIPSRGVFQTDS
IGALKAFDEYLRKRMGLGIALGAAVNQNEPDLEYEGIRIQEKESAGADFFMSQPIFSALQ
AMELLNFYHRYSKRPLLVGVWPLVYRKTIEAIKNAKIVGVSLPKEVYEESLKFWEREDAL
LEWGLEGALRLIRFLKNDGRASGVYIVAPSRNPQVLLDILPDIL
>A0A519ZW28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
GDAVKSEVYFKPEPKGNRFASELVTQIADLNKGVYLDDHLLNSSATNFCIGVAGYPEKHM
EAPSLDSDINYLKQKIANGASYIITQMFFDNQKYFDFVAKCRKEGITVPIIPGLKPISTI
KQLNQVPHRFKVDLPDELIREVVGAKDNDVVREIGIEWCIAQSRELIKAGIPVLHYYSMG
KSDNIKAISEKVF
>A0A4R9EMF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MZ04|TrEMBL
MTTLRDVLDRATPSFSFEFFPPKTDAGARTLWQAIRRIEPLAPAFVSVTYGAGGSSRDRT
VEVTKRIAAETTLRPVAHLTAVGHSVAELRNIIGQYADAGVRDVLALRGDPPGDPNAPWI
PHPDGFAHAHELVRLVKESGDFSVGVAAFPERHPRSPDWESDIRHFVAKCRAGADYAITQ
MFFRAEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIARFAELSGAAFPEELAHRLDTAR
DDPAEGRRVGVAYATAMAERLLAEGAPGLHYITLNRSTATLEIHRNVLNSRSTQHVLAAQ
R
>A0A8J2X7D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygosaccharomyces bailii (strain CLIB 213 / ATCC 58445 / CBS 680 / BCRC 21525 / NBRC 1098 / NCYC 1416 / NRRL Y-2227)|TrEMBL
MRISEKLQTQHSKSEKPTFSFEYFVPKTTQGVQNLYDRMDRMYQSTLPQFIDVTWNAGGG
VLSQLSTDLVETSQSVLGLETCMHLTCTNMPVSQIDEALESARLSGCQNILALRGDPPVN
QESWKPVEGGFRYAKDLVKYIRTKYGDHFDIGVAGYPEGHPENVNDKETLLDHLREKVDA
GANFIITQMFYDADIFVKWCEDVRAMGIQVPIIPGIMPITTYTAFLRRAQWCDIHIPQEF
IDKLDPIKDDDQLVRDVGTDLVVSLCRRLLESGHIRHLHIYTMNLEKAPQMILDRLGLLP
THDEPLDNHLAILPWRKSLNPQRRNEEVRPIFWQRRPYSYVARTSQWAVDEYPNGRFGDS
SSPAFGDLDLCGASLIRQSGKRSLELWSTPTSIQDIAQLVINYLRGELKCLPWSDTALNH
EVDDILPDLVALNQRLIITVNSQPQLNGVKSSDPVYGWGPRDGYVYQKQYLEFLLPKDKL
PKLHEALANDVMLTYFAVDYDGNLTTNHRDGSRANAVTWGIFPGREVLQPTIVEKVSFLA
WKEEFYHICQEWKLNFENHQYNDSVNVLQRLINDYVLVNIVDNDFISSESRIFQLLSSI
>A0A6G3S149|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID14478|TrEMBL
MRTRTTTFSFEFFPPRTDKGEQALWQAVRRIEPLAPDFVSVTYGAGGSSRERTIGITKRI
AAETTLRPVAHLTAVGHSVAELRRIIGQYADAGVRDVLVLRGDPPGDPKGTWTPHPDGYS
HAYQLVELVRSLGNFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFDVED
YLRLRDRVAAAGCDTPVIPEIMPATDARQIRRFAELSDAAFPEDLAHRLEAARERPDDAY
RIGVEHACAMADRLLAEGAPGLHYITLNKSTAALDIHRNVLNSSRSLHV
>A0A6F8Y9B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytohabitans flavus|TrEMBL
MRPGHNRYSHWVALGLPSVLPGGSQPSIGDLIAGPAPTFSFEFFPPKTAEGQPLLWQAIR
ELEPLRPSFVSITYGAGGTTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRHVIGRL
AGVGVRNVLAVRGDPPGNPMGEWVRHPEGVLYAADLVRLLKESGDFCVGVAAFPYKHPRS
PDIASDTARFIEKCRAGADFAVTQMFFDAEEYLRLRDRVAAAGCDTPIVPGVMPVTRMAT
IERSEQLSGAPFPPALLEQFERVADDADAVRRLGIEQCSEMCARLLDEGVPGIHFITLNR
STATREVWQNLPAGARV
>A0A7V1Z8C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmataceae bacterium|TrEMBL
MRIAQLYQRTQPVVGGRALTISLELFPPKTNEGEETLFRDILPQLVALGPSFFSVTYGAG
GGTRERTLRIASRIQQQFGITSMAHLTCTGQSRQTIAAVLDEAQTLGLENILALRGDPPR
GQTQFSPEPDGFAHATDLIRFIRSQYPFSVGAAFYPEGHQEAPDKYRDWDYAAMKVEAGA
EFLISQLFYVAEDFIDCVEYLRHKRGVNVPLVPGILPFLSKEQIRRFTRMCGAKLPDTIN
RRLDQLHDDESVRRYGVEVCTELSAKLLAYGVPGLHIYCLNRVESARELLSNLGLVPVAR
EDSARQEKAAL
>A0A7S3Z0E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lotharella globosa|TrEMBL
MNGHLQFSEKKNKRDLSDIKGGTSTPRSGPSEKIINKINRAVNERRTFYSFEFFPPKTEA
GVMNLYNRIDRMVAKYEPMFVDVTWGAGGSTAKLTLEISSNVQNYCATDVLMHLTCTNMP
RDSVKDALDKAKEAGIRNILALRGDPPHGQDTWEKCDKGFEHALDLVKFIREEYGEYFGI
AVAGYPEGHISSPNLEEDIKHLKLKVDAGADFIMTQLFYDVDLYIDFVKRCRQAEITVPI
LPGLMPINSYNAFKRMIAYTKATVPKEIIAAIEPIKNNDAMVKAFGIELAKKMSQKILRT
GLTPGLHFYTLNLEKSVTKILGGLGLARLPSKGVRPLPWKQSCATRRRNEDVRPIFWANR
PYSYLSRTISWDEFPNGRWGNSTSPAYGELYDYHLMGLKSSSVRDRLRMWGGEVQSEQDV
FDKSTTTTSTPANNNNQPPPTPLERNKQGGVSGLKKRSPFQ
>A0A7Z7GET9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium saccharophilum|TrEMBL
MSSETAAAVPFSFEIYPPRTDAGMPALHETIRLLAAAGPEFISVTFGAGGSTGGRSLEVL
THILRQTDVPPLAHLTCVGSSYEEATTLIREFLDAGITRFLALRGDPPADAAEGEEYVGD
LASAAELVQLIDRVQAERAPYTEAPVPGVPGAARVAPRARVEIAVAAFPNGHPRSRHRLE
HIDALLAKQAAGATFAISQLFFHAHDYLGFVELARAAGVTIPILPGIMPITSPSRLRRVV
ELTGEPLPSDLAVALDVEPTAEGRREIGVRHAAALARDVLAGGAGGIHLYAFNNHDNVLA
VLREAGVRTRTEEISA
>A0A7S6W263|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. YH12138|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGDHFKIEVAAYPEMHPQADSFDLDIKRFCDKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A7S3Z0N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lotharella globosa|TrEMBL
MNGHLQFSEKKNKRDLSDIKGGTSTPRSGPSEKIINKINRAVNERRTFYSFEFFPPKTEA
GVMNLYNRIDRMVAKYEPMFVDVTWGAGGSTAKLTLEISSNVQNYCATDVLMHLTCTNMP
RDSVKDALDKAKEAGIRNILALRGDPPHGQDTWEKCDKGFEHALDLVKFIREEYGEYFGI
AVAGYPEGHISSPNLEEDIKHLKLKVDAGADFIMTQLFYDVDLYIDFVKRCRQAEITVPI
LPGLMPINSYNAFKRMIAYTKATVPKEIIAAIEPIKNNDAMVKAFGIELAKKMSQKILRT
GLTPGLHFYTLNLEKSVTKILGGLGLARLPSKGVRPLPWKQSCATRRRNEDVRPIFWANR
PYSYLSRTISWDEFPNGRWGNSTSPAYGELYDYHLMGLKSSSVRDRLRMWGGEVQSEQDV
FDKFADYIEGKIARLPWCETGIMLETLPLKQRLMAINKTGFLTINSQPRVNGARSDDEVV
GWGDPDGYVYQKAYIEFFASPERIKSLKALASRKEYKTLSYHAVNAKGDQFSNYTDKNAV
NAVTWGVFPGREVLQPTVVDMDSFRVWKVLYRPPSTHHADLPPFITTHGTSRTRPL
>A0A0P6W0S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rossellomorea vietnamensis|TrEMBL
MKPLLEALKERILIADGAIGTLLYSYGVDRCFEELNLSHPNEVLKVHQEYIDAGADIIQT
NTYGANYQKLSRYGLEDSVKEINTAAVRLARKAAGESTYILGTIGGIRGIKQNVSLEEIK
RSFREQLYCLLLEGVDGILLETYYDFEELTTVLNIAKREADIPVIAQVSLHETGVLQNGM
ELKDALQQLELLGADVVGINCRMGPFHMVNSLEEVPLPKRAFLSVYPNASLPNYEEGRFY
YSAEPDYFGDISNELRLQGARIIGGCCGTTPDHIRSVASRLKSREPVIEKEVKKKKVVQL
SSPSISGSLLHEQVREKKTIIVELDPPKHLDTKLFFQGAAALKEAGIDALTLADNPLASP
RISNDAIGSLVKSKYDLTPLVHITCRDRNLIGLQSHLMGLHTLGIHNLLAITGDPAKIGD
FPGAASVYDLSSLELIELIKQNNEGISFSGKSLREHTQFSVGAAFNPNFRHLDASVKRLE
KKKKAGADYFISQPIFGKEQLIRVHEATKHLDVPVFIGIMPLISSRNAEFLHHEVPGINV
PEETRRRMKEAGNDPVTARSVGMEIAKDLLDTAIELFNGIYLITPFVRFDMSIELIHHLQ
EKTNIEREVPYGHHIV
>A0A662CQJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MPNAGLAQFVNGKFYYPFNPEYFVRYGQKLLQAGVKILGGCCGTTPEHIRRMAAELKGLK
PRSRSLSLIGPVTTTAPKVYKERIETQYKTQVEKGWAVSVELDPPKDPNIDKFLKKIERI
APYIQAYNISDCPMARARMSSIATGNIIQQQLQKEVVIHYTCRDRNILGIQSDLLGAAAL
GLNNILTLGGDPPAVGDYPFATGVYDLTTEGLVQLCSALNHGRDLLGNPLGRPTHFYIGV
GYNINDQSLPAFNSLVKKINQGAHFVVTQPVFNLASCWPRLEELKKKNIPVIVGALPLTS
FKQAEYFHYEVPGIIIPEKFLARLEKLKAKEAEKEGVKITIELINELKPAINGILLMISF
NKLYLLEEIMAKI
>A0A2D3RJY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingorhabdus sp. YGSMI21|TrEMBL
MGLIELEEAKRALDAPLFAGLSGDADVSFEFFPPKSEKMEKTLWDSVLTLQPLSPRFVSV
TYGAGGTTRERTHATVARIAQETDIPAAAHLTCVGASKAEIADVARSYWDAGVRHIVALR
GDPPTEGQAFEPHPQGYASAADLVKGLSDIAPFEISVAAYPETHPDADCPQSDLDNLKRK
LDAGATRAITQFFFTAEAFFRFRDAAAAAGIDAELVPGILPVSNVAQTRKFAGMCGAEIP
AWMNDLFEGLDDHPSARQLIAATVAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGK
RPGGTQQEKAA
>A0A5B0AYV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. ANT_H59|TrEMBL
MTKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALCA
RGETDIAPHMSCIGDDKSEIAELLEHYKSLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFKLDVDNLVNKYQAGANASITQFFYNADSYLYLR
ESLEKRGIDTVAQPLVAGIMPITNSSNLMRFADSCGADIPRYVRKQLADFGDDSKAIREF
GFEVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVQALGLIA
>A0A7G7UAG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. PAMC26543|TrEMBL
MGLLEDLKKQVLIGDGAMGTLLYSFGIDRCFEELNLSKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETNLPIMLNVSMHEQGVLQDGTP
LSDALRSVADLGSDIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETADKYFQNSAAEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLVPVTEKHVKVRAKELVT
VQHERTEPGLNEIAAEKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLHDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFISQPVYSEQQLVDIHNETKHLKTPIYIGVMPLTSSRNAEFIHNEIPGIKL
SDSIREKMARAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTSELTSYIK
QKDEQRQNIYLH
>A0A517NT39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium K23_9|TrEMBL
MSLAEHYAGTNCAISFELFPPKTSEGIDKLCNNVKRLMDFNPSYFTCTYGAGGSTQGTTL
EVLKCVREITGLPVASHLTCVGLTAEQLADYLTEAKTLGVEHIVALRGDPPKGTDKFEAV
NGGLHYANQLVDLIREKFADDFGIAVAGYPEVHQEASDAQTDLDNLKRKVDSGADIIITQ
LFYDNADFYRFRDACVKAGIQVPIVPGLLPVTNFKQAQRIASMCKAGIPSVLESAMGESD
EADYQFKVGVDHARQQTIDLVENDAPGIHYYVLNKSDAAEKLLDGLSLGVDC
>A0A7Z0NP07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinispora sp. H7-4|TrEMBL
MALGLPSVLPNPQSAIGELIRDRRPTFSFEFMPPKTAQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRHVIGRLAAAGVRNVLAVR
GDPPGDPTGEWISHPDGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDIDSDTAYFVR
KCRAGAEFAITQMFFDADEYLRLRDRVVAAGCDTPIIPGVMPVTKVSTIERSEQLSGAPF
PPALAARFERVADDPEAVRQLGVEQASEMCQRLLDEGVPGIHFITFNRSTATREIWRNLR
VSTPG
>A0A8J7V363|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marivibrio halodurans|TrEMBL
MPTNLAEKRTAARGAGRTARGGAGPRVSFEFFPPKTDKAGASLEEAIRGLAPLAPQFMTV
TYGAGGSTQSVTRQWVDRVAELGGTPVGHHLTCVGATRAEIDALARSLWNDGIRHIVALR
GDPPQGTTRYEPHPDGYAFAADLVEGLRRVADFEISVGAYPEVHPEAASAAADMDNLKRK
LDAGATRAITQYFFDVETFLRFRDRAHAAGITKEIVPGIIPVTNIESLIRFSEACGATVP
RWLTDLFDGLQEDPETRQMIAASVAIEQCTRLQAEGADSFHFYTLNRANVTRAVCHALGV
RASADKVAA
>A0A7X5ALG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas icarae|TrEMBL
MTSIRFELMPLVGMQEAALSLPAGATVTVTCSPRHGLERTLEATEWLVDRGFCVVPHLAA
RRVRDSAHLESLLERLVALGVDDIFVVGGDGESPLGDYSHGLALLQAMEGLAQRPARVGV
PVYPEGHHAIDGDALERDLVAKASLADYAVTQLCFEAEPLLAWRRRQSRLGLALPVYAGI
PGVMEPKRLLAIAMRLGLGPSMRALRRQSGWLRRLLSPSDFRPDALLEKVEPLLGDGVDG
FIGLHVYTFNRVEPTQRWLEARLRLMAGRPESTSSVADPVTSAGEPLG
>A0A662LQK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MKISTLIEGIDETSFSLEVYPPKIMPINTSPSIQNQISSIFETIEQLISYKPLFVSVTYN
PIGKTKLTSIPIAAIIKQRFNVEVVAHLTGISTPKEEVHRILDLIDYFDINNVLALRGDL
PKEIKSNNNSFFEMQYASELVEEIKQHKYLNMGIGVACYPEGHMECKNEYGTRDFNKDLY
HLKMKVEKGVDFAITQLFYDNKYFYSFIENARKMGISIPIIPGIMPILNYKNIQMITQLS
GAKIPNFLKQKLDNNQEDPEEIKAIGIEHAINQCKGLIGKVPCIHFYTMDKWESIQYILE
ELSEIKKPLLYQ
>A0A1F1ZMH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC28B08|TrEMBL
MSAINRQVAVSSSLNFTTPGRIPFSVEFMPPRDDAAEMRLWNAAEAFHDLGVSFVSVTYG
AGGSTRARTLRVAERLATKPLTTLVHMTLVQHTVEELKEILRGYAELGLTNLLALRGDPP
GDVNAEWIPTEGGLEYAHELIELTKSMPECEHFDIGIASFPEGHFRAGDLDNDTKYTLRK
LRAGAEYSITQMFFDVDHYLRLRDRLAAVDPEHGAKPIIPGLMPITSLRSVRRQMELAGA
SLPSTLEQRLLKAAAGGEERNRAAIREVGIEVTTEMAERLIAEGAPDLHFMTMNNVRATQ
EVLHNLGMAPAWGPDLGHDMVR
>A0A2T1M0H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanothece hegewaldii CCALA 016|TrEMBL
MTTPFRQAIENKKFLVTAEICPPKGGNPKHMIEMGLLLASRVHAVNITDGSRAVMRMSSI
AASVILLQHGIEPICQMACRDRNIIALQADLMGAYALGIRNILALTGDPVKAGDHREAKS
VFELESVRLLKLIAQLNNGLDFNEKSLPDEPLDLLAGAAVDPQCKSWSGLQSRFEKKITA
GAQFFQSQMITDFERLDKFMNQIVAGSDKPILAGIFLLKSAKNAEFIRKNVPGVVIPDEL
IKRLAEASDPLLEGVKIAAEQVKLAQQLCQGVHLMAVRREDLIPKILDEAGISSIA
>R6AYW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia intestinalis CAG:13|TrEMBL
MRLTELLNTENVTISCELFPPKQGAQLDNYKKIVGDMAALKPAYMSVTYGATGGTSDYTV
ELANEVRNVNHIPALAHLTCASSTKEKVASVIQELKEKQIENVLALRGDIPQNADFPLPN
QYKHASELIYDIKSQGDFCIGGACYPEGHPESQTLEEDLIHLKEKVDAGCEFLTTQMFFD
NNILYNFMYKALKHGIDVPVVAGIMPITNANQVKRSIALSGSLVPRRFLAIVDRFGSDPA
AMKQAGIAYATDQIIDLIANGVNHVHIYTMNKPDVAGAILENLSDIYVRD
>A0A1Q5Q472|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bowdeniella nasicola|TrEMBL
MTHTDLYRRSGKTSPVISYELFPPRVPDPHSTVWAGIVKLLNSRPDYVSVTFGALGSSQE
LSRTVLQQVLQRTGRTGRAHPRGR
>A0A1E7H692|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium S3730MH12|TrEMBL
MSFQKRLSANEFVVLAEMHTPKGVNISRLVNDARRMKGRIDAIVVPDMDNGIMRMSALAG
GVLMQQQGVEAIIHVYCRDRNRMALQGDMLAAYVLGVQNLLVTHSEDIEQSDHRDARQVY
DLDEVELVQVIATLNQGKDMGGFELDGVPEFTAGCTIAPYSDEKGLAGELEAAAKKIEAG
AGYIITPPVFDLDSFAGFMEKAKELNAPIIPTVFLLKSLAIAQYIARSEPGANISEDLIK
RIRKSSDRELEGIKIAGETVAALKDLSQGVMLQTLGWEHKLPEILDMAGL
>A0A258FDW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium 32-62-9|TrEMBL
MNQRTFSFEFFPPKTAEGAEKLRATRAQLAQLNPKFFSVTFGAGGSTRDRTLETVREIQA
SGSDAAPHLSCIGSTQDNIREILNEYKSQGIRHLVALRGDLPSGSMDAGEFNYANELVSF
IRSETGDWFEIEVAAYPEIHPQARSWTDDLANFKRKVDAGANAAITQYFFNADAYFRFVD
EARAMGVSIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLASIRAFGLDV
ITDQCERLLACGAPGLHFYTMNQAGPTTTIWQRLGLS
>A0A0Q4E9L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf208|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGLSFEFFPPKSEKMETQLWEAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKDEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPVAKVAAA
>A0A2M7K8K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium CG_4_8_14_3_um_filter_34_18|TrEMBL
MIHHIQNKIYHIEVLPPKQDSEKLEKDLEIFSNKYLRVMDSSYCTCITDNTMGLLSFQGT
EIIEELDLPVMSEQVMIHLNTFHTKDDLDNILDICKSKGIRYLLIITGDGSERLPKLQPS
DVGATDVESVTSVELLKYINHEYPDTFVLGAAFNPYEPEEHEFEKMKRKMKAGATYIITQ
PLIERNEVVDRLLEKYPEIPVIIGTWMSRKLHLLSEAVGYEIPGNAEYDPISTLKMLHKL
YPGCGVYLSLLGFKTQYDLIKDIWV
>A0A7L2R5Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxylabes madagascariensis|TrEMBL
LFSDPAGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLK
EKVFAGADFIITQLFFRPETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLE
VPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKR
LGIWKEDPR
>A0A1U7U7Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carlito syrichta|TrEMBL
MVNEARGEGSISGGESSQDSSRCSTPSPDPERHERLREKMRRRMEAGDKWFSLEFFPPRT
GEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMT
CCRQRQEDITGHLYKAKQLGLKNILALRGDPIGDQWEEEEGGFSYALDLVKHIRSEFGDY
FDICVAGYPKGHPDAQSFEADLKHLKEKVSAGANFIITQLFFEAETFFHFVKACTAMGIT
CPILPGIFPIQGYNSLRQLVKLSKLEVPQKIKDVIEPIKDNDDAIRNYGIELAVSLCQEL
LASGLVPGLHFYTLNREVATTEVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWAS
RPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEE
SVFKVFVHYLSGESNQNGCKVTCLPWNDEPLAAETSLMKEELLQVNRQGILTINSQPNIN
GKPSSDPIVGWGPSGGYVFQKAYLEFFTARETVGALLHALKKYELRVNYHIVDVKGENIT
NAPALQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRKLI
QHIHDNYFLVNLVDNEFPLDNCLWQVLTDTLELLNKPAQNQTETEAP
>A0A2P5SX61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pantoea edessiphila|TrEMBL
MGIYYTNQYKKLNQNWLNYNEKFNISFEFFPPRNKIMEKILWNSIDFLSKLKPRFVSVTY
GTNSGTRKLTYNITKKIKDITGLEAVPHLTCINATRNELRSLAHKYWNNGVCKIIALRGD
LPKQNGNFKPEMYCYDLISLLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKCKIDAGAN
RAITQFFFNVDNYLRFRDRCVAIGIDVEIVPGILPISNFRQLKHFAEISKVHIPLWMYEL
FNGLDNDYETCKMIGAHIAMDMVEILSNEGVKDFHFYTLNRYEMSYSICHALGIKPDKL
>X6J8B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L103C565B0|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A5C5U5M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas marina|TrEMBL
MTPISFEFYPPKTDEQRAQLDRTAARLKGHAPEYVSCTFGAGGSTLSYTAETVQHLLQTH
GLDAAPHLSCVGGTREEIAELLARYRDIGCRRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAQHGDHFHIEVGAYPEMHPQAEDALADLKHFKAKIDAGANAAITQYFYNADAYFHFVDA
VRALGVEAPIVPGVMPISNYSQLRRFSEQCGAEIPRWIAKKMQAFGDDADSIREFGADVV
ARLCERLVAGGAPALHFYTLNLARPTQAVLARFG
>A0A1G5D8S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira sp. Nsp13|TrEMBL
MESQKKFAPTFSFEFFPPQTREGIEKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETV
LEIQAEGYAAAPHLSCIGSTRENIRTMLQKYRDGGIRHIVALRGDLPSGMAQWGEFRYAD
ELVSFIRKEFGNAFHIEVASYPECHPQADSAQDDLLNFKRKVEAGADSVITQYFYNADAY
FNFIEACEEMGIGVPIVPGIMPINKFSQLARFSDSCGAEIPRWIRKKLEGYGDDSASIRA
FGLDVVTDLCDRLLSAGAPGLHFYTLNSAGLTTTIWQRLGL
>A0A261EXB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoscardovia radai|TrEMBL
MSTDHSPIFSLEVFPPKRNAAVGTIYDTLDGLQGVDPDFISVTYGTGKQSDRTATARISN
TIRQEYDIPVVAHLTAQYLDKDGADEALDLFEQAKVRGVLALRGDSVEGREPAGVFEHAS
DLAAYIRSTHPDLDVYGACYPEGHPEATSLSQDVENLKKKVDAGVSHLVSQLFYDNSDFL
NFISLAREAGIDTPIEAGIMPVMNVGQVRRMGKICGARIPHALDRMLDRWQDDKKSLRAA
GIVYASQQIADLVAQGVDGVHLYTMNHPGVTRRIWQNVGDLFEPPSR
>A0A315U5I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. H-02-3|TrEMBL
MIPTRIEIIPSEGIVEQVTALVPLSTTLTVTCLPHHGIERTMRAAVQLSLHGYSVIPHLA
ARSLPGRVELTEILRDCNVAGIGEVFVIGGDRKQQAGPYGSALPVLEDIAQYTGGVMRAG
VAGYPEGHPAVGALDLVDALLAKQHLATHVVTQMCFSAPKILDYAALLRREGVQLPVWAG
VAGAVPRTKLVSLAAQIGVGSSLKFLSRKGPLARKLLSGDRYSPQSLVTGLQSQPGSIAG
IHLYSFNNLDAVPDGPDQALTPAALQPALIRRATRDN
>A0A1H4XIV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tsukamurella tyrosinosolvens|TrEMBL
MSEQSRTVLDRLDAVRASGRMPFSVEFMPPRDEEGEARLWRAVRTFERMDPAFVSMTYGA
GGSTRDRTVRVTGEIAETTTLLPVAHLTAVNHSISELRALMGSYADQDVRNVLVLRGDPP
GDPMGKWVRHPEGLKYASEVVELVRELGDFHVGVAAFPEGHHRSPDLDTDVRYFANKLRA
GADYSITQMFFDVDDYLRLRDAVVAADPEQGAKPLIPGIMPITSLKSVVRMAELSNAKIP
ESMRAELRAAAGDGPEENRAAVRAVGIDIATRMGERLIAEGAPALHFCTLNFAKATSEVL
ENLGMLPVGV
>A0A2N4YHH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tabrizicola sp. TH137|TrEMBL
MTTPRISFEFFPPQTLDASFRLWETVQMLAPLKPSFVSVTYGAGGTTRKLTHEAVGAIGR
NYGLNVAAHLTCVDATKAETLEIAEAYAAAGVTEIVALRGDAPKGAERFTAHPEGFASSV
ELVEALAKTGKFKLRVGAYPEPHPDAGFAGADVEHLKRKVDAGATSAITQFFFNVDTYFR
FRDACVAAGIDVPIIPGILPIISWDGAKKFAARCGAHVPGALDEAFRVAARDGREDLLAL
THCTTLCARLIEGGVEDLHFYTLNRPHLTQAVVRALGITPEVALEKVA
>A0A352UXG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmobacter sp|TrEMBL
TPRISFEFFPPQTLDASFRLWETVQMLAPLKPTFCSVTYGAGGTTRKLTHEAVTTIGKNY
GLNVAAHLTCVEATKAETLEIAEAYAAAGVREIVALRGDAPKGATRFTPHPEGFASSVEL
IEALAATGKFTLRVGAYPEPHPDAADTLADVRWLKRKIDAGASSAITQFFFEAETFLRFR
DLCAKEGITAPIIPGILPIENFAGVKKFATRCGSAVPQWLDDAFTTAKRDGREELLSVAL
CTELCDTLISEGVEDLHFYTLNRPHLSRDVCHALGITPEVALEKVA
>A0A8H6CTD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella circinata|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVRHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTFYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMTSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFGLLKGLEVKGLTTPATPLTESA
GNGAVDTEPIANGTAATAVAN
>A0A844J4Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella sp|TrEMBL
MKITDILSQGKPTLSFEVFPPKTEDKYDSVEKAAAEIAKLKPAFMSVTYGAGGGTSKYTV
DIASALHHEYHVTALAHLTCVSSTKEKVGQVLGELKEAGIENVLALRGDIPADAPDKREY
NYASELIREIKETGDFCIGAACYPEGHVESANKTIDMDYLKQKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVVAGIMPVTNVRQIIRSCQLSGTYLPTRFKAIVDRFGEDPAAM
KQAGIAYATEQIIDLIANGVNAIHVYSMNKPDVALKIKENLSQIL
>A0A8F4W8W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter sp. L9-4|TrEMBL
MTGTVRDLLSGEQPTWSFEFFPPRDEAAEVQLWTALRQLERLQPSFVSVTYGAGGSTREG
TVAATERIAAETTMLPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WAAHPQGLRYAAELVELIKGIGDFSVGVAAFPERHPRSRDLDSDTDMFVAKCRAGADFAI
TQMFFRVEDYLRLRDRVSARGCDVPIIAGVMPVTNARQIARIVQLSGQAFPDELAERFAA
LDGDTPEQKRAMRALGVEVATQMCQTLLAEGVPGIHFITMNRSTATREVYASLAGIGVDT
GAPAAAVGV
>A0A8D9T3D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus E1410|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A351YFA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp|TrEMBL
MKVIDLITSTDKTAFSFEILPPIKGKGIDTLYQTIDTLREFDPKYINITTHRSEYVYKDL
GGGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESIFVPEHDGYSHAVELEAQINDFNRGLFVDGSPAEVTKTPFHYGVACYP
EKHEEAPNMESDIYWLKKKIEAGAEYAVTQLFYDNRKYFDFVKRVREAGINVPIIPGIKP
FTKLSQLNMVPKTFKVDIPEPLSSEAARCKTDEEAAALGIEWCVSQCRELIAAGVPSIHF
YTVSAVKSIHEVAKQIF
>A0A519RFZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTEHIENANGKSLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEYKE
LANGLLQKKVVKKRPGTVGICAAIQNKYEVDAIPHILCGGFSKEDTENFLIDMDFLGIQN
VVALRGDAVKSETYFKPERDGNQYASELVTQISNLNKGIYLDDELQNSSCTNFCIGVAGY
PEKHMEAPSMDSDIHFLKQKIKNGATYIITQMFFDNKKFFDFVAKCRKEG
>A0A367JVY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus azygosporus|TrEMBL
MKVIDKIKKAEAENRPFWSFEYFPPKTPQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
ELTTEIVATAQSVYGLETMMHLTCTNMPVQQIDDALEAAKKCGCQNILALRGDPPKGQAN
WESCENGFEHAIDLVRYIRKKYGDYFCIAVAGHPEGHIDNPDKEDDLLRLKEKVDAGADL
VVTQLFFDVDIFIEFYKKARAIGITVPILPGVFPIQNYSGLKRVIAFNDNFVPQKIWDDL
EPIKDDDTAVKEYGINLAVEFIKRFREVGINGFHLYTFNLERSSRLVLERLDLVAPLENI
KPLPWSPSLNTKRAKENVRPIFWKNRTKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
INLRYPVEQCISMWGTPKSVDDIALTFARYCKGEIAGIPWSSQQLDPETDIIRQRLAAIN
LLGYFTINSQPAVNGVKSCHPIYGWGPKNGYVYQKAYLEFFVSPEKLNELIDKISQNPQV
TYYAVNKQGDLRTNTTSDEPNAVTWGVFPGKEIVQPTIVESVAFMAWKDEAFELWNRWAR
IYERDSESAKLILDITDSYYLINIVHNDFQDENGIWRLFDLEIDGEISRKLLQSSVAR
>A0A0L1LG02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio lentus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLIAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRP
>A0A1M5CE95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariniphaga anaerophila|TrEMBL
MKVIDVINKSEKTVFSFELLPPLKGNDAGRIYNTIESLVEFDPKYINITTHRDEVEFREM
PDGSIVKRTVRKRPGTVAIAASIQHKYGIPVIPHILCGGFTKSETEHVLIDLHFLGIENV
LALRGDGAKNQHVFQPENDGHSNANELVEQIVNLRNGIYLEQDLKNNTPLDFCIGVAGYP
EKHFEAPNKEQDLFYLKQKVDAGADYIVTQMFFDNKVYYDFVKKCRDMGITVPIIPGIKP
INMKNQLTVLPKIFNIDLPQELSKELAKCKNNEEARQVGTEWAIHQSKDLVANHAPSLHI
YTYGISDNVKQIVKSVF
>A0A653A7R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfatiglans sp|TrEMBL
MSGMATLKTPSKLEKILAAGHLAVTSECGPPRGSDPEAITRKAEMIKDHVDAINITDNQT
SVTRLCSLASCIHIKLMGLEPILQMVVRDRNRIALQSDILGAASFDIFNMLCLSGDHQTF
GDCSTGQNVFDIDSMQLIQTVRRMRDEGKFLGGDEIKRPPRMFVGAAANPFADPFEIRVP
RLAKKVAAGAEFIQTQCIYNLDKFEKWMQGVRDRGLHEKVHILAGLTPMKSAGMAKYMKN
RVPGMDVPDEIIKRMSGVPKEKQPQEGLDICVEAIQRLKEVEGVHGFHIMAIEWEDKVPE
LVERGGLYPRPQVD
>A0A252A1W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter tropicalis|TrEMBL
MTDGLSNWLSGKHIDGLLLRNFQAPIPILSFEFVPPRTDAMEQRLWHCIRRLAPLAPRFV
SVTYGAGGTTQAGTLSTVLRLKRETDLIPAAHLTCVGATREEVDDLARCYRDAGVNHIVA
LRGDPPAGAADYSPRPGGYAYASDLVTGLRRIADFDISVAAYPETHPTASTPDADLDNLK
RKLDAGATRAIMQYSFDSEIYLRFLDRCLAAGITAPIIPGIMPVSNYEQIVRFSAVCGVT
VPAWLRHLFDGTAKNPELRRIIACMVAVEQIRTLQTYGLNEFHVSTLNRSDLTCAIAHIL
GVRPTEMNASHNLTGLLETTENPDERDTSTDFNPTEGTQEGAPPFMLRTLFG
>E0MLQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ahrensia sp. R2A130|TrEMBL
MTNDHMSHIPASMEVSAKHVHDGKLTAGMLPSGTRVYITDVGVDPVEDLIRAAATVRGLG
YSPVPHVPARRIESEAALDARIAGLVNEGGVDDILIIAGEAPSQMGPYSQSLDILQTGVA
DRRGVNFIAVGGHPEGNPAYLGVDVMNVLRDKLAFGAQSDAEFRIVTQFGFDGKKFIDWA
KALKADGIDTPIHLGVAGPAKITTLIKYAAMCGVGNSLNFFKKRTGAIAMLATKHSPEEV
VSPIEQAWLSGETNITQMHVFPFGGLQASADWLHERGSYQTAPLGQAHA
>A0A5F1H913|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E2562|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1G7A9L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospira trueperi|TrEMBL
MTLDPRTTSDLVSALPLCSRLPDDVKVSFEFFPPKTDKMAESLWAAVKRLEPLGPQFVSV
TYGAGGSTRERTHDTVARIARETTLKAAAHLTCVDATREQVDDVARRYWDAGIRHIVALR
GDSPESDGVYRPTPGGYAFAADLVEGLKKVADFEISVAAYPEPHPEAASPEADLDALKRK
VDAGATRAITQFFFDVDVFNRFRDRAAAAGITVPIVPGILPVSNFATVTKFAGMCGASIP
QWMAETFAGLDDDPDTRKLVAAMVAAQQCRALAAAGADQFHFYTLNRADLTYAICHVLGV
RPPEPVPSPAMAEA
>A0A081CRB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium rubi TR3 = NBRC 13261|TrEMBL
MTKTEADRHVTENFKLSFEFFPPKNADMDVQLWETVEELSRWHPDFVSVTYGAGGTTKAP
TLVAVDRMISIAGLPTASHLTCVDASKREVHDVVEELRAIGVKRFVALRGDPSTGPGTAY
KPHPDGYENAAALVRGLRELGDFEISVSAYPEKHPESESDSVDIDMLKCKADNGATRALT
QFFFDNDIFERYMERVTKAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPSFLDDRFAGY
DDDVVGRAKVAADVAAEQILDLQRRGINEFHLYTMNRAPLVNAVLENVGYRPMRKSAA
>Q1LTU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Baumannia cicadellinicola subsp. Homalodisca coagulata|TrEMBL
MSFFYASQREALNQYLAEIKGNVTVSFEFFPPRSSDMEQMFWQSIQRLSQLKPSFISVTY
GANSGEHQNTYSLIKEINKRTGLVAVPHLTCINTSPWELHEIIQEYWHNGIRHIVALRGD
LPPDNSSRQNITMYGLDLVVLLKKIGDFEISVAAYPEVHPEALSAQSDLINLKKKVDAGA
NRAITQFFFDVESYLRFRDRCLTVGIDIEIVPGIMPVFNFRQLQRFATMTNVKIPLWMNT
MFDGLDLDIESSKLVGASIAIEMIKILSREGVKHFHFYTLNRDELTYTLCHIIGIRPEKI
TI
>A0A7C5I789|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Solibacter sp|TrEMBL
MDSLRASLEAGEFVCSAELVLGRDHTTSEVQAFLDEAARQPEGIRFLSLTDLPGGNPALP
PESFAAAVLERGLVPIAHLSGKDVNRAYLEGRLHHLARLGVRDLLALTGDAQKDGFQGPG
KPVHDLDSVQILWLIREFQKGISYQLGTRSVRLAPYEFFAGAVVNPFKVREPDLMMQLYK
MELKIASGARFLITQVGYDLRKLYELKQYMVCVGLDHIPVLANVYVPTAAIARMMQSGEL
AGCLMPPDLLRRLETEKKPQRLERAALMVAAARGLGFAGAHIGGFGLTHRDIAGIVDRSM
EIGAGWRSRLDELTFESAGQFYLFPKRPDGLSDGGGSLQNALERPRPSWVQRLSALAHRL
CIAEGSAGARFFQRHLANGAASWKASLCRAALAPSVWYRKAFFGCMSCGDCIQDYLSYAG
CSVSGCYKQLRNGPCGGSRPDGSCEARPGIPCLWNRVYEASLALGQNPRRFAGILIPPRD
WRLDGSNSLVNRLAGRDNLSRRQIFSPYPGDSNVSDR
>A0A7C5AWC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Solibacter sp|TrEMBL
MGANRSEEFRKQLARRVLVADGAMGTMLYARGIFINRCYDELNLSAPALVKEIHEEYVKA
GAEILETNTFGANRARLAGYGFAEKLRAINQAGVRLAREAAGGAAFVAGAVGPLGIRIEP
LGPTSFEEARAMFREQIAALVEAGIDLLILETFANLNELREAIFAAREIAGEELTVVAQV
TIDDDGRLPDGASTEDFTRKLDEWPADVVGCNCSVGPKAMLETIEKMVRYTKKPLSAMPN
AGLPATVEGRKLYLCSPEYMAQYGRRMLWAGVRIIGGCCGTTPEHIKMLKAEVRSLEPAH
ARSIVVEEPAPRIEALKPVPPAEKSKLGAKLAAGRFVTFVEILPPRGVDASREIAGARLC
AEHGIDCINVPDGPRASARMSAQVTCQLIQQHAGIEAVLHFCCRDRNILGIQSELLGAHA
VGIRNLLCITGDPPRMGTYPSATAVFDVDSIGLVNIVSNLNRGLDIGGNPIGSQTTLLIG
VGANPGALNLEEELRRFEWKVKAGAEFVVTQPVFDVSLLERFLRRIEGFRIPLIAGVWPL
TSHRNAEFMVNELNVPVPAEFMNRMQRADTTEKARREGIMIARELVERVRPMAAGVQLSA
PFGRYEMAIEVAEVLGSR
>A0A7C1RVL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MICGMLFFALLVLTQRDRMESNFRKDISNPDRFVVTMELVPGEQSRGRSVDTVMRIAEDA
LRDGRISAVSITDNPGGHPSLSPDVLGSEIVSRGMDVIVHFTCRDQNRVGLESRALQLGH
LSIRNILALTGDFAGKGFAGQGAPVFDLDSVSLLSMLRMMNEGTLARGDREDFFAGCAFS
PFKRTEEESFCQYFKLFKKVGAGASFAITQVGYDARKFHEALCVQRDWGMQIPTLGSVYL
LTPKVAGVMCEGRIPGVVVTKRLLGTVQEEWEDRDRGKAALIDRSARLAVILRGLGYRGV
HFGGVHRDFGVLSAVLDRMEEIKHRWREYLPDFDFPQKNGFYLYHRDPDNGLSAGEIIPC
RSRASHADRVVFQAYRAIHRTFFNHDAPFASIYSSLCQRLEKRPLASLLVRTVEDVSKKF
LFSCQECGDCGIQHLAFFCPESQCPKHTRNGPCGGSRNGMCEVHPERRCVWFRAYRRWAS
VNQPERIKEEYVPPRRWELNRTSSWINFHLGRDHQGEELFKKSK
>A0A661JG21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKWRQRLLKGEFLKVVETLPPKGVNGKEFEKRLIPLKGKADALYVPSLQGAVMRVSSWAA
AKYLQDRGYETIFEVSCAHQNRLALQAEVLGGYLLGLENVMVVSGDDPKLGDHPEAKVVF
DVDVVELLEGIKGLREGHDMAGGDLDGVPELCIGSKVDASAQGQGLEQQMREMEQKVRLG
VEFFITTTVYDLGQLERFMERAREFEVPVIAGLMVLKSAGMARYINKHVEGVLIPEETIT
RLLKAPDKIATSVQIAAEMIRGIRELCHGVNIIPIGWEDKVPAILEEAGA
>A0A7V4ZS17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTFKECLESGKFSIVVQLQPPKGIDLSEIYESVERLKGRVDAINIPDLQHAIMRLGSLSV
CALLREKGLEVIFNLSCSHRNRLALQSELLNAYVLGIKNVLIIQGEHPSIGDHFEAKPVF
DLDLMGLLGAVKRLQEGYDLMGNDLQGKPQFFVGTEVNASAKGHVLELEVMDMEKKIRMG
ADFFFTNSIYDPGLLENFIKKVSHFKVPIIAGITILKSVGMARYMNKHVEGTYIPDSIID
RLMKAPDKQKESVEITSELIKEIKPLIQGVQIIPIGWENLVPHILDQVGL
>A0A7Y1UP59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MRVTEHLERSTDPFITFEIIPPTRGGDLQSLLGLIEDLMAHRPPFIDITSHAAEVVYEEV
PTGYEKRIKRKRPGTLGVCALIQNKFNIDAVPHILCEGFTREETEDFLIELRYLDIDNVF
AIRGDSSGYEKRLEHGRSRNLYASDLIAQVADMNKGVYLEELLDASPTDFCVGAAGYPEK
HFEAPNLTADVARVKQKVDAGAEYVVTQMFFENQHYFDFVGECRSQGITVPIIPGIKVLA
TQRQVVSIPRTFHCEIPAALAEEVMNTDEQYSADIGVAWAAEQTRTLLERGVPSIHFYVM
QSARLVNGVLAKLDV
>A0A7C7W387|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MSTRNKADRAVQKRLLEGMTYELIPLKNLADQSMFLPAGSTVSVTCSPAKTVDDTLDLCA
HYGGQGFTVIPHLAARMVEDEEHVERIARRINELGIRTVFCIGGDAEPRGPFTDTAGFLR
SFLDRRPEIDTVGVGSYPDGHATIPDQALVDGLVEKQEMIREAGLGGYMATQMCFDATTI
ADWLKGRRDAGVDLPCHLGVPGAIDRTRLLTISIRLGIGHSARYLKKNSASVIRLLSPGG
YNPSKLIGPLSGVAEELDIVGIHCFTFNAVDTTEDWRQKVLRKLG
>A0A7V3CCQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTRLKEELQSGRFVVTSEIAPPKGPDLSEFLEKARLVKDRVVAINVTDNQRAIMRLSSLV
ASAALVREGIEPIYQLACRDRNRLALQSDLLGAHAFGIRNILPLTGDAVAQGDQKEAKPV
FDLTSVKLMALVQKLNQGLSYGDHPLSGKTDFFVGGAVDPKNIGAKAFFQKMEEKIKYGA
AFFQSQPVYDLAQVEAFHRYCEEHKVKSLIGVLLVKGPKQAAFLNSHVPGIRIPEEIIHK
FNGAAEPLQVGIDFAAQQIRELRAISHGIHIMTVGREDLVPEILDRAGL
>A0A7J4N9S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccales archaeon|TrEMBL
MSVSRLQETLDSGKFAVTAEIGPPRSCETERLREMARMLKGSAHAFNLTDNQAANVRMSS
IASSVICLQEGLEPVMQMTCRDRNRIAMQSDVIGASALGVRNVLCISGDHQVFGNHPQAK
NVYDIDSIQELMVLRNLCQGTNWSGETLPEPPQLYLGAAANPFADPFEFRAARLAKKADA
GAQFVQTQCVLDLERFKKFMSLVVEKGLHERVHIIAGVIPLRSHKAALFMRNKVAGMSVP
DELVDRLRKASDPKEEGIRSCVEMMNELLSVKGVHGVHITAIAWEDIIPRLVNEAGVRP
>G0PNQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis brenneri|TrEMBL
TALEDTHQFRALDMIRWIREEYGNYFSIGCAGYPLGHPQAPSYKADLMYLKAKCDAGANF
VITQLFFEAETFEKFVRDCREIGITQPIIPGIMPIMGYESIKRIAKLSQLEIPQHILDDL
EPIKHDDDAVQKYGTERCIAMCRRLLDNGSAPSIHMYTMNREGSIREILKSLGLWKLEGD
RVFPWKNRSQHPIRCLESVRPIYWSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSY
YLSNLTTLRNNEDRLAMFGNTIESIEDVKQVFINYITQAPNATGVKVTSLPWTEAETGVQ
PETSLITEQLVWCNHNGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAEL
SEKLIQIIERDFPIRVNYHAIDKDV
>A0A7L9U9X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. LPB0304|TrEMBL
METPNFSIEFFPPKTPEGAEKLRVTRRKLAELNPKYFSVTFGAGGSTQQGTLDTVLDIMA
DGHLAAPHLSCIGATRESIRAILQQFQDKGIRRLVALRGDLPSGYGGAGELRYANELVEF
IRAETGDWFHIEVAAYPEVHPQARSPQDDLLAFERKIKAGANAAITQYFYNADAYFQFVD
NAQRLGIAVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTSLCERLLAGGAPGLHFYSMNQAVATTAIWQRLV
>A0A7C3V0N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MAISAFEEKLNSGKFVVTAEIGPPKGTDVSEMVKHIRLLKDRVDAMNVTDHQSSVMRFPS
IGGCLLIKELGGEPILQMTTRDRNRIALQAELLFAYSRGIRNVLCLTGDAIDIGDHKEAK
PVFDLDSVQLIRMVRTMEGGKDMAGNDLKGGVEFYVGASCNPGCDFIEPQLLKFEKKVMA
GARFFQTQGVYDLSSFRRFMQYARQFDVKILAGIIVLFSYRMAIYMNENVPGVFVPEEVL
EELKGLTGPEALKAGIAIAARTIRALKEEGLCDGVHLMAIGREHTIPEILEISGL
>A0A7Y3DKT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MRVTEHLERAADPFITFEIIPPTRGGDLASLLGLIEELITHRPPFIDITSHAAEVEYVEG
PTGYQKRIKRKRPGTLGVCALIQNKFNVDAVPHILCEGFTRQETEDFLIELRYLDIDNVL
AIRGDSSGYEKRLDHGRSRNLYATDLITQITEMNKGIYLEDLLDAAPTEFCIGAAGYPEK
HFEAPNLTADIARVKQKVDAGAEYIVTQMFFDNRHYFDFVEACRAQGITVPIIPGIKILA
TQRQVVSIPRTFHCEIPAALADEVMAAPEADAPHIGIEWATVQTRELLEAGVPSVHFYVM
QSARLVNGVLAALDV
>A0A7C8DU22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
DMGLHEKCYILAGVTPMKSVGMARYMGKSVPGMDVPEPLINRLKGAGKGKVAEEGIKFAL
EQIEEFREMEGVAGVHLMAIEWEHKVPEIAERAGMLPRPVV
>A0A809ELH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus delbrueckii subsp. bulgaricus|TrEMBL
MSLTALFKNKTVFSLEVVPPKKDSPKEAILPTLQQLQSINPDFISVTSGAGGSDHYTGTV
QIADLIQNQLNILAVAHVPGLYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDF
NHANDLVAFVHQNRPDFSIASACYPNCHPEATGFVDDIAHLRTKVDAGADYLISQLFFDN
QAFYDFQEKAEIAGIHVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILNRYQNSKEA
MREAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHR
S
>A0A520YFS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIADLYAADEGPVFSLEFFTPKNDAGRKALFRAVERLQAVKPGFVSITCGAAGTTRERT
ADLAIELQNAFGLTAMAHLVCTGTTQSELEETLRHMQANGIENILALRGDPPKGATDWAP
VEGGFAHANELAALVRKGFSLGLGGACYPEKHHEAPSLAADIQNLKRKVEAGAEFLITQL
FFDNEKYWSFVAQVRAEGIDVPVVPGIMPVLNLTNLQRIASLSPGTSIPSELEDALRQAG
DDDEAALRAGVSFAAKQCRALLAKGAPGIHFYTLNRSKATLRTYAEL
>A0A0F0CMK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophus magneticus|TrEMBL
MKSFKEKLMSGKFVHTTEIGPPKGVDFSSVLTELECVKFLVDAVNVTDQQSAVMRLGSIA
SSRVLIDNGFEPICQVTTRDRNRIALQSDLLSAFILGVRNIMIMTGDHPILGDHPSAKPV
YDLDAITLLSAIKVLESGFDLAGKKLNASPSFLVGGVVNPGADPLEPEIIKMEKKIENGA
MFFQTQSIFELGKFEKFINSIKHFRSLIKILGGIVPLRSAKMARYMNDNIPGVSIPENII
TRIDKALNIEEESVLIASEIMREIKGMCDGIHFMPIRSNHLVAKILDIAGVRKGE
>A0A3N5TII7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MDQMKKRRKVLVVGSIPDFHQGVGKSLETQFDVVSASNEVEGLSKARTERPQAIILGYLE
PRGSSFRLHKRLREGWITKHIPQLVVDVHFPGQPAKAWTPQEAMQMDAEDYLSIEPGDVT
SVAQSMEVLKLTEKIDVKLGEKANPLKEAILDPGTFCVTWEQIPGRGAFEIQQEQVIDNV
AKAAELERIHALSVTDNPGGNPAISTEMLCAEIKRLGTEPLVHLACRDKNRSEVESMLYG
LAAGGVRNILVLSGDYPSPEGFEGRPKPVFDVDPVNVVRLIERMNAGLEHYAMGKKVTLA
ATDFYAGVCVSPFKKLESEQMAQYAKLKKKIEAGAKFIITQVGYDARKFHEVLQWLRVHH
YSIPALANIYILPHGAAKLM
>A0A1V5MGM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin419|TrEMBL
MYIDITKGNIQEDLPHEDIVYHEKTVEAQIKGSVAENPLLKKISIGKKIIAVELDPPIDT
DIDFFVKSAIKLKEQGVDAITIADCPVASARVDSSLLACKLKREFDITVIPHMTCRDRNI
NATKALLLGLNIEGVNNVLVVTGDPIPTAQRDEVKAMFSFNSAVLANYITNLNETTFSTP
FNICAALNVNARNFKHQLDYAKKKVESGVSMFLTQPVLTRQAVDNLILARKELKCGILGG
IIPIVSYKNACFMNNKISGISISEEIIERYRDISKEEASELAVRISVQFAKEIEPFVDGY
YIMTPFKRIDIVTKIIGTLLRNS
>A0A084G1D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudallescheria apiosperma|TrEMBL
MHIRDMLEEAKRTHQPSFSFEYFPPKTAQGVQNLYDRMERMFMLGPKFVDITWGAGGRIA
ELTNEMVVQAQTLLGMESCMHLTCTDMGLEKVDEALRKAYKAGCTNILALRGDPPRDKEK
WEVTEGGFNYAKDLVEHIRNTYGSHFDIGVAGYPEGCDDNKDEDLLLEHLKEKVDKGAGF
IVTQMFYDADNFLRWVKRVREKGITIPILPGIMPIATYASFLRRANHMGCKIPPEWMAAM
DPVKNDDLAVREVGKRLVADLCRKLLASGEIYHLHFYTMNLATATTMVLQDLDWLPSAER
PLKQALPWKQSLGLGRRQEDVRPVFWRNRNKSYVLRTQEWDEFPNGRWGDSRSPAFGELD
TYGIRLPGTSEQNRKKWGEPKTVRDVANIFVDYLENRYDSLPWSESPLTSEGQVIRDELV
ALNKRGLITINSQPAVNGVKSSHPIHGWGPANGYVYQKSYLELLVHPALYPDIIDRIKRH
PDITYYAVTKDGTLESNAPTEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFLNNDF
QQPKTIFEILEGLEVKDMDAPAIPHTHEAPTSAPDAPANGPSAKEPAQANGAN
>A0A2E9KYM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIIEMYHNRPFVFSIEVFPPKTEDGMTNLQKKLRAFSAFKPDYISVTYGAGGGTRQNTQ
YLAGFIGNELGIEVLAHLTCVSHTRKDVSLLKERFLSEGVENIMALRGDPPTTEKKFEPM
PGGYRYASELIEDLSRDRRFGIGAAGYPETHIDAISSQMDRYFLKHKIERGAEFVISQFF
LENQKFLSWRDQLYREGVRIPIIPGLICAQSFSQIQRFAKMCGCMVPSQLIKNLERFAGN
AEDSLRVGLDHAEKQLEGLIKEGITGLHLYALNRSEVVNDLGQMMIGLKSRTDLKSNLEN
HGRLGF
>A0A1B8SWD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia rettgeri|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSEEMEQTLWKSIDRLKNLKPKFVSVTY
GANSGERDRTHSIIKDIKDKTGLIAAPHLTCIDASPDELKAIARDYWNNGIRHIVALRGD
LPDNSRKPDMYAVDLVELLKGEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPAWMSKMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A3A4RDE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSESKLEQILTKGEFAVTSECGPPRGADAEVIRKKGEMLKGFVDGVNVTDNQTSVVRMS
SISSCVILKELGLNPIMQMVTRDRNRIAIQSDILGAAALGINNILCLTGDHQKFGDHASA
KNVFDMDSIQLVQTVKLMRDEGKFLGGEELKGSPKMFIGAAENPFADPFEIRVPRLAKKV
AAGVDFIQTQCIYNLPKFEKWMKLVRDRGLHERVHILGGVTPFKSVGMANYMKKSVPGMD
VPDELIERMKAAPKEKKAEEGINICIETIQRLRDIEGIHGVHVMAIEWEEMVSEIVKRAG
LFPRPHIES
>A0A496Y9P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLKESLEKKKFVVTSEVQGAVDEAPEQLVKSLELVRGRVDGVTVPEVEIEGVVGDSIKT
CEVLNKNRFEAIYQTTTRDKNRIQLQKDLLQAHDSGVENLLVFTEDYRITGDSLQEMMFF
HVDAGKLESVLQHMREGRTVDGGELGKGADFVVGSGVESGWGKNIPDLEMKEMEAMAKIG
AGYFLSTPVFDVDGFEKFLKQVNTFGIPVIAEVMILRTAGMASFLNRHIKSGMVPEWVIK
KLAKAIDKEKASIEIFAD
>A0A355EQ57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKPDSKLAAKISGNDFIFTAEYLPVAGTGLTIDPKIFGSAALTAVNAADNHYGVSMSSLA
ASAALRQAGIEPVFQIVTRDRNRIALQSDLLGAAYLGIRNVLCLSGFHQTLIGCGESANV
FDIDSIQLIDIVRKMNGGHLSDGTKIQGDFAMLIGAAANPDLKPLELNIIRLGKKIAAGA
DFIQTQAVFDVDNFKVWLKAVGDAGLAGKTAILAGVLPLKSAAQAVELTSTHTDFIIPET
IINRLTAAGDAGAQEKEGVSIAAETINKLKGLPGLKGVHILSGGNESRVGELLAAVT
>A0A660QHJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotogae bacterium|TrEMBL
MREALEKSKGVILEVLTPRGSNLRKFLEFTEKMWETGIDAFSVTDMPLGKVRMAPWAGAH
FLLERNMDVLMHFTRTTRNMIRIQSDLLGSYALGVKNLLILSGDDPKHGDYPNTTRVNDI
SITDLIKLAKSLNDGKDLGGRTIKPSTDFYVGAVFNHRDNTDLVKAKEKIRAGADFLISQ
PVFDVKEVENVIYELNEVKLVLSVVFFKSEKQFKIFSQVPGVNIPRKYLEDLENKSDEYI
RDYTLSKVLEIVDTLKSKVDGFYVVGIVRDIESVRRLVEIAKGG
>A0A2D7I4D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MHIADLLTNGPTCSFEFFPPKTEKGAEALYETIRKLEVLKPSFVSVTYGAGGSTRELTHD
LVVRIKNSTSLDAIPHLTLVCHSQDEIQGILTRYAEAGVSNILALGGDPPKGLTGYDRKQ
DAFQQAADLVGFIRKFNEKGGLHPDQRGFGVGVAGFPEGHPATPNRLDEMDYLKAKVDQG
ADYIVTQLFFDNSAFFDFRDRCILAGITIPIVAGIMPITTTQGMRRIAELAGGANISAGL
QRAIARAGSDTEAVANVGVHWATEQCRELLDQGVAGIHFYTLNQSSATTEIYRSLGLRDS
AALQRSASS
>A0A2E9H9L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MQISDIFRSRQPSISFEFFPPRTEKGAESLLATIHELKELNPSFVSVTYGAGGSTRDLTH
RLVLRILQETSIPAVPHLTCTCHDAPEIEAILNQYAEAGVSTILALRGDPPRDRPDYDRS
QDTFRYASDLIRFIQEFNHSDQHPSGGFGIGVAGFPEGHPETQNRMKEMDYLKAKVDAGA
DYICTQLFFDNHDFLDFRERCHLAGITVPIIAGIMPITTPEGMVRMAELAAGVHFPAKLQ
RDLAGLEDSPEAFAGAGTSYATEQCLELIKEGVVGLHFYTLNKSSATRQIVANLELDGSR
Q
>A0A2D6BJF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MPDAPSFLTSGDPVLSAEVLPPDRADRAAVVAAARAVREAGARVLFFPDAPGGRARVDAI
AAAAAVRGELGGPCVAHVNCRDRNRVALEAALLTAAFAGIDGIKAVTGDPVCRDIGQGVY
DVGSVGLVGMAVQQAKDLPVFVGHTVGHTDPAGSEARLREKLEVGAHAVVTTPTLDADDL
LRTLDRLDPLPVPLLVGLTLIPSSEVLDYLCAELPAFRVPDRLRAALAGSTSPADALQRG
LDAAVSVAEAVRDRTRGFHVVPAFGRWQGAVPLLKAL
>A0A3A4ZU26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTAEYSAGSRLEKIFRSGQKALTGECGPPRGCDVDHFKHKASFLKGNVDAVNVTDNQTAV
VRFCSMAAAKILLEMGVEPVMQMVTRDMNRIGLQSNILGAAALGIKNLLCLTGDHQSFGD
HPQAKNVHDMDSVMLAHTVKTMRDEGKMVSGTELQGRPRIFIGAAANPFADPQEFRVIRM
GKKIAAGVQFIQTQCIYNMERFRKFMEMANDMGLTEKCYIMAGITPLKSVGMANYMKKFV
PGLDVPDSYITRLKGVPKDKVAAEGIKIAVDQIHECLAMKGIAGIHLMAIEWEERVPEIV
EAAGLLPRPVVD
>A0A1C6DQB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Flavonifractor sp|TrEMBL
MSIAQLFQEKSVVFSCEVFPPKKTSPIETVYRTLDQLQDLRPDYISVTFGAGGSAGDNLT
GRIAAAIQDQYHIPSVAHLSCVNYTRDEVAGLLDGLKAMGIENILALRGDMDPNHPPKTD
FQYASQLIAFIKSRDNSFHLSGACYPEGHIESPDMVSDILNLKKKVDAGAEHLVSQLFFD
NDDFYDFREKARIAGINVPIQAGIMPVLNKSQIERMVYLCGASIPKKLARMLSRYGDHPA
ALRDAGIAYAIDQISDLVASGVEGIHLYTMNNAGVARAIFDRVSTLFTV
>A0A1F0KQW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC066H02|TrEMBL
MTTVHPALSFELFPPRSHASCESLLHTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSNAE
LHRIGVDYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEY
A
>A0A661HRW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MFEKFCDVLCLEKRFITVEINPPHGASIDALIEDIKKHKLQDKVTGFSCTDNPLAKLKMS
GVLSAIKVQQTFNKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKYSDQPD
VKGVLERDSTLLLSIIHHLNKGVDYSNKALNPAPKPIYPFAVTNSTAKDMNSLKKRMVKK
LNYGARAIITQPVYDLNNAKELLALFEEAKELSIRDTAKEAHLVLGQFPIVRARTANFID
DKVPGISVPKDIIDEMNLAAMDGEEKEQEVGFALSKRIFDEIMDLHGKVHLMTHNRFDLC
SELIG
>A0A661L8D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRLREALQRKRFVITSEVQTPIDEDPQALIEKLELIRGRVDGVTVPELEIEGVVVDTVKT
CELLKKNRFESIYQTTTRDKNRIQLQKDLVVAHEVGVENLLVFTEDYRITGDSLQEIMFF
HVDVGKLESVLEHMREGYTVDGQELPFKAEFVVGSGIESGWGKDVPELEMKEMEQMAKIG
AGYFLTTPVFDVDMFEKFMKQVSTFGIPVIAEVMILRTAGMASFLNRHFKSGMVPDWMIK
KLAKAVDREKASIEIFADIVKGLKDLCQGVHIITIGGEERLRYYLDAAKLR
>A0A644VU43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MPVINTKQIKRIVSLCGAKLPKKFIKIMNKYEYNPEALRDAGIAYAIEQIIDLISSGVDG
VHLYTMNNAYVAKRISTNIFSILDTINNCEKVIN
>A0A7D0KRZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
AKLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A7T4H5M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLQTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKHIHQATHALFNHQSLG
>A0A7V8XBE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MTTLRDLITDGRIHVVDGAMGTMLYQKGIFLNVCFDELAVRQPALVEEVHAAYVEAGAEV
IETNTFGANPFKLAQYGLASDTELLNAAAARVARRAAGSRAAVVGAIGPLGVRVEPFGEL
ALAEAEAAFGRQVDGLLEGGVDGFCLETFSDIDELLAAMRAVRQRTDLALMAQLTVAEDG
RTTYGTAPEAFGPALADAGADIIGVNCSIGPQVVLEAIERLARVVATPLVAQPNAGLPRE
VGDRKIYMASPEYVAEHARRMVEAGARFVGGCCGTTPEHVRAIDKFVRAAQRTARSAGAP
TATTQPAQAEVATVPLAERSRLGARLAAREFIRTVEIVPPRGIDPAPMIAQARALAAAGI
HAVNIPDGPRAQSRMGALISGLIVERETGLETVVHYACRDRNLLGMLSDLLGAAAAGLRN
LLIVTGDPPKMGPYPDATAVFDIDAIGLTNLVTRLNAGLDPGGNAFGAPTRFVHGVGVNP
TAPDIEHELRRFAWKAEAGACFAMTQPVFDVAQLERFLPRVELLGVPVIAGIWPLVSLRN
AEFLANEVPGVSVPREVLDRMRRASDRGKEAALAEGVAIAREMIAAVTPSVAGVQVAAPM
GRVEVALEVLG
>A0A7K2EGD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermaceae bacterium|TrEMBL
MQPPNRFDPPSSLDKGVSVLIWKATWRVSQPADPSVSKLSVAEQQSKPPPNVSFEFFPPK
SDSMEAKLWESVARLTPMAPRFVSVTYGAGGSTRDRTRRIVTKIAQDTPLLPAAHLTCVG
ATKEEVLGIAVDLWKAGIRHIVALRGDPPEGIDAKFEQHPGGFRDSIDLIEGIRNCEITP
GARFEISVSCYPEQHPHSRGWDQDIAFLRAKQDAGADRAITQFFFEPEVYFKFLDRARAG
GVTMPIVPGIMLQPNFKGMKRIADLCQVTLPNWLYEVFEGTGDDAVTREFITANVAAELC
HKLSDQGVNDFHFYTLNRASLALSTCRLLGLKPQAVA
>Q2N880|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter litoralis (strain HTCC2594)|TrEMBL
MTAAPPPLDPQHEAQTAHDSPLFSGLPGDIETSFEFFPPKTDKMSETLWRSVETLKPLGP
RFASVTYGAGGSTRSRTHKQVVRIQSEAGIPAAAHLTCVQATREEVDEVARHYWDEGIRH
IVALRGDPPDGAAHYTPHPGGYANAADLITGLKKVADFEISVAAYPEVHPDSPDRQADIA
NLKTKFDAGATRAITQFFFDPECFFRFRDEAAAAGIHGEIVPGIMPVLSFAAVQRMSTLC
GTAIPDWMAGLFDGLDDRPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAIC
HMLGLRPKGATA
>A0A1B1BCD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseochromogenes|TrEMBL
MTGKDVPKLEEARDSIPRGTRINVTFLAGEDLGMRLAAARAVKRLGFVPVPHISARRLPS
RVHLEEFLAGLAADGTAENVFVVGGDPARPEGPYEDALSVIRTGLLQRYGARHIGISGYP
EGHPAIAGPTLWSALTDKTAALGTGRLDGDVITQFGFDVAPVLSWLEAARARGVHLPVRI
GVPGPAGVRRLLGYAARFGVATSASVARKYGFSLTNLMGTTGPDRFLHALAKEYDPARHG
AVKVHFYTFGGLRATSEWIARFRQADHRR
>A0A7S7AYV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter hepaticus|TrEMBL
MCSFSFEIFPPRKDENIKNLDAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEK
YKIPSIVHLPCIHSSKEKITQILQQCKDRQLNKILALRGDVCNNLEKSKDFSYASDLISF
IQKYKDFEIYAACYPEKHNESKNFIEDIHYLKNKVDLGTNKLITQLFYDNDFFYTFKQNC
ALANINIPIYAGIMPITNKRQVLKITQLCGSKIPAKFTKILEKYENNALALEDAGIAYAI
DQIIDLITSGVDGIHLYIMNKSRAAIKIYEAIKYLIKVS
>A0A699Y1R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RTEHGDAFHIEVGAYPETHPQATDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWIGRKMQAYGDDAESVRAFGTEVV
TRLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLRG
>A0A7Y4VY47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MPTLRELLADGRVHLFDGAMGTMLYGRGVFLNICYDELNLRQPDLIREIHREYVRAGAEI
LETNTFGANPRKLAQHGLGAETERINRAAAELARAAAGSRAAVAGAIGPLGIRIEPFGET
SVAEARADFARQVAGLLEGGVDGFILETFSDVEELRAALEAVRGLTDLPVIAQMTVGTDG
RTHYGTEPAVFGPMLEAMGADVIGVNCSVGPHGVLEAVEQLAAVVSKPISAQPNAGLPRD
VGDRKIYMASPEYMGSYAKRIVEAGARFVGGCCGTTPEHIKAIAGFVQSVAPRHQSLTAT
AEHAAPGVPPVPLADRSLYGGKLARGEFITTVEIVPPKGVDPAPMFDQCRALKAAGVDAV
NVPDGPRAQSRMGALLSGLMIEREVGLETVVHYACRDRNLLGMLSDLLGAAAAGLRNLLL
VTGDPPKMGPYPDATAVFDIDAIGLTNLVARLNRGLDPGHNALGAPTKFVIGVGVNPAAP
DLERELRRLHWKVDAGAEFAITQPVFDLAQLDRFLRQVESFRLPIIGGIWPLVSLRNAEF
LANEVPGVTVPEEILARMRRASERGREEALAEGVAIAREMLAAVRSRLRGAQVSAPLGRV
PVALDVLSP
>A0A644ZFX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MSQIEKKLPVSFEFFPPKTPEGAQKLRGVRAKLYECKPEFCSVTYGAGGSTQEGTFNTVK
EILAEGVDAASHFSCIGATRDSVREQLALLKVMGVRRLVALRGDLPSGYGMGGEFHYASD
LVAFIRQETGDYFHIEVAAYPEVHPQARSADADLKAYVTKVKAGANSAITQYFFNADAYF
RFVDDTRKLGVDVPVVPGIMPIMGASQLMRFSDACGAEIPRWIRLRLQGYGDDVDSIRAF
GLDVVSAMCEQLVKGGAPSLHFYTMNQSAATLEICRRIGL
>A0A2H1JG10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium antiquum|TrEMBL
MSQANLSTLLKSARYEILPTAGVVDRVHEYVVPGRVITVTASTGLTLEATLSTAEQLQAL
GFQAVPHIAARMVQSRTELEEIVARIAQAGIDRIFVPAGDATPPAGGYAGALDLIVDLAS
MAAPIQHLGVSAYPETHPLISDDVTVQAMWDKRDYATHLVSNLCFDPGVIATWLARVRAR
GIELPLVLGIAGKVELTKLARVAGKIGVGESTRFLRKNTATFSRMAKPGGYNPKKLLDKL
APTLDNPAMGVVGLHIYTFNQIKDTEIWRRKQLAALGHTDEATISNG
>A0A103XE54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cynara cardunculus var. scolymus|TrEMBL
MKVIEKILESTAAGDAGKVVFSFEFFPPKTEDGVENLFERMERMVAHDPTFCDITWGAGG
TTAELTLEIARRMQNMVCVETMMHLTCTNMPVEKIDHALETIKKDGIQNVLALRGDPPRG
QDKFVQIQGGFACALDLVEHIRKSYGDYFGIAVAGYPEAHPEVIESNGLATPEAYEKDLA
YLKRKVDAGADVIVTQLFYDIPSEITAALEPIKDNEEAVRAYGVHLGTEMCKKIMASGIK
TLHLYTLNMEKSALAILTNLGLIEESKISRPLPWRRPTNLFRVKEDVRPIFWANRPKSYI
SRTIGWEQYPHGRWGDSSNASYGALTDHQFMRPRARDKKLQEEWVVPLKKFDDISEKFMK
YCLGQLKTSPWSELDALQPETKIIDEQLASINLKGWGPAGGYVYQKAYVEFFCYEEKLKA
LVEKCKANPSLTFLAVNKEGNLLSNVGKNDVNAVTWGVFPAKEIIQPTVVDPSSFLIWKD
EAFEIWSRGWAQFYPEDDSSRSLLQEVQKTSYLVSLVDNDYVNGNLFAVFKGF
>A0A0R2U4W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|cyanobacterium BACL30 MAG-120619-bin27|TrEMBL
MMPISGTIGLLLQKTLASGQPALTAEVMPPRGGDPSRSLAAAGALRGWVHAVNVTDGSRA
VMRMSSLALCRLLLDAGIEPVLQLACRDRNRIALQAELLGAHALGVRNVLCLTGDPVRAG
DQPGARPVNELEAVRLLQLVQQFNGGQDPVQGELPDGPTDLFAGAAADPQSASWSGLKSR
LLRKKQAGARFLQTQMVMDADALKRFVGDLAAPLDLPVLAGVFLLKSARNAAFINRVVPG
AHIPQAVIDRLAAAPDPAAEGVAIAAEQVGAYLQIAQGVHLMAIKAEERIPAILQQAGLK
PLAPV
>A0A2J6HK54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinilabiliales bacterium|TrEMBL
MNIAEKLRNTSDTLFSFELLPPMKGDHIQAIYDTINPLMDFRPSYINVTYHREEVVYKKR
SDGLLEQRSVRKRPGTVGIAAAIMHKYNIEVVPHLICGGFSKEETENALIDLHFIGVNNI
LVLRGDPDKSTRMFTPDPDGHENAIGLLNQVMDLNKGVYLDDDIVNNAETHFSVGVAGYP
EKHPEAPNFDSDIRHLKSKVDAGAEYIVTQMFFDNRHFFSFVDKCRAAGITVPIVPGLKP
VSIKNHLSVLPKTFGVELPEALTSEMEKCTDNAAVRQLGIEWTAEQARELKQAGVPSIHL
YTMGKADNIREIVRKVF
>A0A2W6IKR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MAAPTSLRARAFLDAFSLEVSAKAMPALHAEAARIPRGTTISIPWLASEDDDARLAAARR
VRELGFEPMPHLSARRIGSRVVLERFLQRAANEAGVAQCLLIGGDLATPAGPFADSASII
ETGLLERAGIKAVAIGGHPEGHPVMGSVGCWQVLEHKCQAIEARGMAPMIITQFAFDADI
VLAWLDALRARGIDVPVLVGVPGPASIARLARYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDHLVGSLTDAHGLVSPHFFPFGGIAQSLDWIKRHRPQASAVGG
>A0A229RCJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis alba DSM 44262|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDTADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPNGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTLRTLHTSIKLSGAPAPRRLLDRLEPLA
DDPKAFRAAGIDAVTELCERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A2J6I4J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinilabiliales bacterium|TrEMBL
MERTVIQHINDAKETLFSFELLPPLKGQDFGSIQKSIDPLMDFNPSFINITYHQEEVEYE
TLASGLMKKNVVRKRPGTVGISAAIKFRYGVNVVPHLICGGFTREDTENALIDLNFLGVN
NVLVVRGDPQPGMKSFVPEADGNKYAIETVIQIANLNKGIYLDSNIRNSRSTNFCVGVAG
YPEKHSESPNMDSDIHFLKKKIEAGANYIVTQMFFDNKKYFNFVDICRKNGITVPIIPGL
KPISTMNQLAIIPKTFNVELPAELVKEVIKCKNNEDVRQLGVEWAIEQSKELKSAGVPVL
HYYTMGRSDNIRKIALEVF
>A0A3R9PSI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIEVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2J6HPW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinilabiliales bacterium|TrEMBL
MKVIDIINRAEKPFFAVEFLPPLKGHSMEKIDKAFSNIADLEPAYINFTTHQKEIVYYER
EDGLLERRIVTKRPGTIGLSAAVMYKHNVTVVPHLICGGFSKEETEDALIELNFLGLENV
FALRGDPPAGQRLFVPEKNGHRYAAGLVKQISEMNQGTYLDPNIKNPDASDFCIGVAGYP
EKHIEAPNPETDLMHLKQKVDAGADYIVTQMFFINDRFYEFVDNCRKIGINVPIIPGIKP
VTMRTDADLIPRTFNIDLPSELCNDIRNCHSNEEARVIGTGYAIEQVKDLLEHNVPGIHF
FSLGMTKNIRQVIQQSFR
>A0A2W7ISQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Humitalea rosea|TrEMBL
MDGTPPPQSPPPPGTLARWLTGPRFGALPAPTDLPPPALSFEFFPPKTDKLEEQLWACIR
RLEPLAPRFVSVTYGAGGTTQARTHATVARLAAETSLTPAAHLTCVGATRDEVDAVARQY
WEAGVRHIVALRGDPPAGTETYAPHPGGYAQAADLVAGLKRVAPFEISVGAYPETHPTAV
SAEADLDNLKRKIDAGANRAITQYFFETDVFLRFLDRALAAGITVPIVPGILPVSNFTQV
AKFSAMCGASVPGWMARLFEGLEEDTTTRTMIGAVVAAEQARLLQANGVDEIHFYTLNRP
DLTYAISHLLGARPKA
>A0A2P2CHA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|metagenome|TrEMBL
MRNKRHATTVIRLLTAARYEVLPTASTEDKLLEHVPRDRTITVTASPSKGLEATFDLAER
LHGHGYVVVPHLAARMVSGRSELEEIVDRLVGKGITRVFVPGGDAEPAGDYRDALGLLED
LAALGSPFAHVGITGYPESHPTIHDDLTVQSMWDKRRYATHIVSNLTFDPAVVRDWVRRL
RARGVTMPLLLGLPGPVERAKLLGMATKIGVGESTRFLAKNKGLFARLAAPGGFTGESFL
EKCAPALGEGALVEGLHVFTFNQIAETEAWRTDMLERLRS
>L8GA37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21)|TrEMBL
MYPACKQERDMADSPTTDKITDKIAALPQDASYFSLEFFPPKTAMGSTNLRARLDRMSRA
LRPLFVTVTWGAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSKALVDDALKAAKEAG
IQNILALRGDEPRGEYKDALEEGKEGEEEFVWAIDLVKYIRKKYGDYFCVGVAAYPEGHA
DGSHPTEQSLEHDLPYLVDKVQAGADFIMTQLFYDVDAYDNFEKVLRGHSSGAFKTIPII
PGLMPIQSYQILRRTTKLSNAKLPESIIDRLDAVRTDDEMVKKVGVDILAEIVESVKATK
QRTKGPKGFHFYTLNLEKAVAFILERANLIPSFTPVLTSDAFAVDDITDTIPLPQLLING
EKKSRRQSSVGSGPHNFVIIDREEASGFETTGAEAAVPKNGVNTRANTLAISEGEGALGR
EATWDDFPNGRWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRPDITSIFVQYING
TLSALPWSDEPITAETNLIKDELVKLNQKGWWTIASQPAVNGAHSQDEVVGWGPKGGWVF
QKAFVELFVPTPDWARLKPLLEGNGEVSFLAQSASGEFLKSKLDLGPGEEGTETNAVTWG
VFPGKEIVSPTIVEEVSFRAWAEEAWQMWGEWAAVFGNSGEESRRFLGGVAKDGWLVNVI
WHDFVGMCKAKKGRSEEEGYKGLWDVLIEA
>A0A2D3UX02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramularia collo-cygni|TrEMBL
MDKLTDKIAALPADATYFSLEFFPPKTQQGFANLNARLSRMAHSLRPLFVNVTWGAGGST
SAKSLALAELTQRELGLTTCLHLTCTNMSRKLIDEALEQAKVLGVRNILALRGDPPRSDE
YRDDSMPDAEGDDSNKDFTWAVDLVRYIRKQYGEHFCVGVAGYPEGHSDQSHPEHQSLEH
DLPYLVEKTAAGADFIMTQLFYDVEAYQHYEKRLREHESGVFKTIPIIPGLMPIQSYQIL
RRTTKLSHAALPQEMLKRLETIKGDDEAVKRVGVDILSEMVQVLKDSPGTGPRGFHFYTL
NLEKVVAQILERTCLIPQEDAVAEEEVIAEDDFXIVDEVKKKQRRRKSSMANSQSRNRLV
VNRTRASSTSSNRTSAVHEVPDDEAGIPREQINSRSNTLAISEGEGALGREATWDDYPNG
RWGDARSPAYGEIDGYGVSLHCSVPDARRLWGEPKSVHDISESFRRHLEGEIEAIPWSEE
VLQPETLGIKNELLGLINKGWWTVASQPAVNGVRSNDPTYGWGPKNGFVFQKPFVELFIP
SADWKTLSNKLCEHPQITYFAGNAQGDFVSSGETSINPVTWGTFAGKEIITPTIIEAVSF
KAWCEEAFGIWGEWQRVYRSGSESSKLLERIRKDYWLVSVIHHGFLEEGALWXDLLEA
>A0A436CYX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.006.04.2.1|TrEMBL
SIELAPAQAPTFAPPADCFPLGSRVFLTHLPGKPEALQIEAARRIKELGFVPVPHLGARN
FNSEQDYIDLVTAHSRNGISEALFLGGNPALFPGPLGEATQLLAHPVVKDSAIRTAFVAG
YPEGHPSIVEAVLTDALRRKLDICAEQSLEARVVSQFAFDGDMIAAWASSLHTAHPGLPV
HVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLFNIVADRNPAEILQTMAASYPAPT
APLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A436CZP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.006.04.2.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A2A2YDJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium AMD-G1|TrEMBL
MSRSLLIAALRSPVRPTVSVEFFPPKDAEGGARMLKVAETLKPLGIDFASLTYGAGGTSR
DTTITYGAELVKMGIPLIGHLTCVGHSREELAGIISQYDKAGFSGILALRGDPPKGQKDF
VAHPEGFAHAQGLVRQIAAEQPDRFAIGVAGFPERHPDAVDDLSDIRFLAGKVAAGADFV
TTQLFLDNEDYFRFVARARAAGVSVPILPGIMPVLSLKQARNFCGFCKARIPDALVRELE
ACGPDEEAQRKVGVSWAVRQARGLVARGAPGYHVYILNKAESAVELFAALRA
>A0A329VTI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus sp. S9-53|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSINRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWKNGIRHIVALRGD
LPENSEKPKMYGVDLVELLKKEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFRQLKRFAVMTNVRIPSWMTRMFD
GLDDDPESANLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A5C4J3V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura soli|TrEMBL
MGFEVVCEVEPPTRPDLTRVRHQIGVLSPVADSFLIPDNHIGRATVSSVAVAHEVQAMGA
RGIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVYGDKPSAGGRTSELTVRAMMDETRAA
GEASAFAGCGPFQVGVTSGLRRVPAWKKTADFTFVQVSYSMENLLRWRESVEVDGPVYAG
VMVLASARMARNLASSIPDIDIPAELVEAVERDRSAGVAAACEQVLAVRESGAFDGVHLV
PVSRYREVAAVLERELG
>D4F035|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edwardsiella tarda ATCC 23685|TrEMBL
MIGMSFFHASQHDALNQSLAELQGRIQVSFEFFPPRTPEMEQTLWQSIDRLSTLKPAFIS
VTYGANSGERDRTHSVIKGIKERTGLEAAPHLTCVDASREALRAIARDYWQSGIRHIVAL
RGDLAAGAGRPEMYASDLVALLREVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGA
NRAITQFFFDVESYLRFRDRCAAAGIEAEIVPGILPVSNFGQLQRFAALTNVRVPQWMMA
MFDGLENDVETRKLVGANIAMDMVKLLCREGVKDFHFYTLNRAELSYAICHTLGVRPQA
>A0A2P2BW79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|metagenome|TrEMBL
MTSSSRRGIGQRVREGERSFSFEFFPPKDAAGEEQLWTAISELEPYGPTFVSVTYGAGGT
SRDTTVRITGRIARETSMLPLGHLTCVGHTREELQAILASYAAAGVHNVLALRGDPQDGP
RAEWTPTEGGFTYASELVALAAGDFSVGVAAFPDGHPAAPSLERDAEVLLAKQQAGAEFA
ITDMVFRATDYVALVERCSAIGVDIPILPGIMPILNLGQVRRMAELSGRELPGEVVERIT
AYADDPTALRAEGIALAAEMCESLLEGGAPGLHFYTLNRSKATREIFAALKITV
>A0A101MAN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium freii|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEATENGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNTDVDQLIDHLKEKVDAGSSF
VVTQMFYDAENFIEWLKKCRAKGITVPIIPGIMPIQTYASFIRRSNWTKVQVPPQWMEAL
EPVKNDDSAVRDIGKTLIADMCRKLFAAGIKHLHFYTMNLAQATQLVLKELDLSPSDESP
IQRPLPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDISDIFVNFLTGKLDRLPWSDSPITTEAHDIQEDLLN
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLLDELITRIEKNG
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCHDAASPSRKLIQHVMDDWYLVNIVDNDFHRSNAVFELFNGLEIKDLNVEVAGKPLTNG
HAEPNGIAAN
>A0A357TD99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MVSLKTDSRLEKLLKDGHFVVTAEIGPPKNADASIVKNKARMLKGFIDAANITDNQTAVV
RLSSIASAVHVLDVEMEPVIQMTVRDRNRIGLQSDLLGAYSLGIKNVVCMSGDHQIIGNH
PESKGVYDLDSIQLIQAVKNMRDKKEFINGELIQGTAPCFFIGAVASPFLQPEEMNLMRL
EKKIRAGADFIQTQCIYDMKKFEKWMSQVRDMELSSQAYFLAGLMPLKSSKVARYMQDNI
PGIGIPETIIRRMERAKEPAKEGIKLAVEQIHWLKTIEGVHGVHIMAVGWEEVVPEIVER
AGLLPRP
>A0A1S1BIJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC034B08|TrEMBL
MFEASPSTRLSASAPIDREGAPVIRRPRPKRQRTALSFEIIPPRPSDSVAKMDELIAGLA
AYNPDYVSVTSSRRSEWLEGTAAVISRIAETTDLRPIAHLACTAGTREELTEWIRTLIDA
GVRGFLALRGDLPETGMPEHYLQYATDLLNLIEEVQEEEAFRLAAGKLALSVACYPKGHE
ESRNFDHDLDVLLTKQRLGADFAITQLFFEAQDYLDFVEVARLAGVRIPLIPGIMPMTSL
KRVRRMGELSGLEVPEVVEKQLLEADDEYETGMQLTANLAREILDAGTGGLHVYTHNNLA
VTRDFLDRIGIQ
>A0A1Y2RF11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium IBVUCB2|TrEMBL
MKVTDHIKQAKDTLISFEVLPPLKGKGIEALYKHLDPLMEFKPSFINVTYHRSEHVFKKT
ADGNFQKVVIRKRPGTESICAAIMNKYTVDTVPHLICGGFSINDTEDALINLRYLGIDNV
LVLRGDAAKNETAFEPEPGGHKYASDLLKQVANLNAGIYLEDELKGTHKTEFCIGVAGYP
EKHFEAPNMDTDLQYLKAKVDAGADYIITQMFFDNAKFFAFEKACRDIGITVPIIPGLKP
IYTRKQLTVLPKTFSIELPSDLSTAVMQCKTDEDVEKIGIEWLLNQSRELKKAGVPVLHY
YTLGRPLMVAEVVKNL
>A0A1S8GE86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKILDLVSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADIIQTN
TYGANEAKLRMYGLENQVTQINKAAVKLAKAAVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEKVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQLALHEAGTTQNGN
DVNGILTQLLDYGANIVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGCYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPAHIEGMKRVIANVTPVTEKQIVQRQQVVH
IQTKRAITHVTLAEKARKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGSATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIEEIYEATKHLEKPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMDGHETQESAIEEGIRISQELINAAMKYFNGIYLITPFLKYEITENLVKYVK
EKQEVKEGIN
>A0A4Q4ICP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporolactobacillus sp. THM19-2|TrEMBL
MRTSILNELKKRILIGDGAMGTLLYSYGIDRCFEEMNLSHADDIRHVHEAYINAGADLIQ
TNSYGANAIKLARYGLEKEVRSINTAAVQLARSAARPETFVVGTIGGIRGLRQQPSSLSE
ITDSFREQAETLLDGGVDGLLLETYYDFDELRHVLKIARKMTDRPIITHVSMQEPGVLLN
GLPFASALSELENLGADIVGTNCRLGPFHMVQALSGIPLPKHAFLSAYPNGSLPDYRDGK
LYYETKPEYFKKYAVKFRNEGVRLLGGCCGTTPVQISAFRQGISELEPLVTKSVTEPVES
IQITVRENELETPLYKKAISGRSVFVEYDTPRNLKTETFFKGVRALQNAGADAITMADNS
LASPRISNSAIGRLIIEHFTIPPLIHLTCRDRNLIGLQSHLMGLDILGLHDLLIVTGDPT
KIGDFPGATSVYDLSSMQLIELVKKFNRGISYSGKSLRHPTHFRVAAAFNPNVRNLDRAV
QRLKRKIDCGADYFISQPVFDKKRIVEISQTLSGVSAPVYLGIMPLTSSRNAEFLHNEVP
GIQLTDEVRQRMALAAEQGKAQERQTGLAIAKELIDTAMQYFRGIYLITPLSRYSMSVEL
IQYVKEKERILSDLARLHSHSAR
>A0A1S9XZ40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRATLNVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A4R1F570|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cocleimonas flava|TrEMBL
MKDHSYSFEFFPPKTEVGVEKLSQVSKELSHYNPAFYSVTYGAGGTTQDATKGTVLSIQK
ETGIATAPHLSCIGSEKEQIRQMLNDYKDNGINRIVALRGDLPSGMFEIGDFHYANELVE
FIRAETGDHFQIEIAAYPEKHPQAKNFDADIENFGRKAKAGADRAITQYFFNADAYFHFM
DSLEKAQIDIPVMPGIMPITNFSQMARFSDAIGAEIPRWLRMRFESYGDDVESIQKLGNE
FVTGMCERLLEQGVPGLHFYSMNRVEPSLAIWNNLGLSEA
>G9PI43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. oral taxon 849 str. F0330|TrEMBL
MLDNEPTEPTAAIEGRNDDPGDAERATSRSLPTVSLELFPPRAGKAASATWGRIDRLLAT
GPDFVSVTYRPAFVTDPVPGSGEKGRWQQRDAPRVRAVQEESNPSEGVLAHVLGSSAVPL
MAHLTCIGYRKREAVDIITRFLRMGVRRFLALRGDPPTGTRADDVAGELRHADALVRVIR
EVEADYFGDGRRHVTIAVAAYPATNDHIEAIEVLASKQAAGADLAITQVFYDPADYVALT
NAASYAGVNIPILPGVIPLTDLGRLTRLEALTGVKVPDALRSSLGSASGATLVERGIGAT
LDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDAVDRGYLQAT
PGRGPSFLRCGSPGAAVSSRHPVQPHTTITKENA
>A0A3N2C3W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plantibacter flavus|TrEMBL
MTTTEPACPRRTPFSFELYPPKTLDGGLALARTVEHLAAAGPEFISVTFGAGGSSRTASL
DVLRSIRTSTSVDPMAHLTCVGSTHAQASRLIKDFLDAGVHSFLALRGDPPAGAVEGDAF
LGDLGSAAELVQLIGRVSAEHEPYAEGSLVGLPGAVQLGRRHRPRIAVAAFPNGHPRSRS
TTQDLDTLLAKQAAGATLAITQLFFHADDYLAFAERARRHGVTMPILPGVMPITSPARLR
RVLELSGEALPSDLAIALEVEPDEAGRIDIGTDYSARLIRDVVAGGAPGVHLYAFNQHRT
VLDVLHRAGIPVQGDRTVRHPIPDPLTSKDAR
>A0A1B2ZAT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MKVTEHIEQAQGKTLFSFEIIPPKKGSSIQELYDNIDPLMEFNPPFIDVTTSREEYIYIQ
REGLLEKKITRMRPGTLGICAAIAHKYNVDTVPHVLCGGFTKEETEYLMVDCHYLGLDNV
MALRGDAMKEQQYFEPTKGGHNYALGLVEQLSDMNCGKYLNDRVESKHCADFCIGVAGYP
EKHLEAPSMKNDLRRLKQKIDAGAHYVVTQMFFDNQKYFEFVKMAREEGIDVPIIPGIKP
LAVERHLQLLPQVFNLDLPQSLIEAVEGCKNNKEVREVGIEFCIEQSKELMEFGVPVLHY
YSMGKSDNIKAIASALF
>F3BGL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas distincta|TrEMBL
MDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVIIYDIQDESSRTNQDRP
FAFKQTVDPREYSHLLRNLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDLQNVVLVGSP
SSIGDIKLSLPDAYKALAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQGCQFFISQA
VYDAQATIELITSYARTCKAQGITPQRIILTFTPCGGEKTLEFMQWLGISVPEATKWRML
DADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINLYRLLKAIME
LNLAEKLIA
>A0A4S0KTN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1C.F.Ca.ET.187.01.1.1|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPEAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLRGRQPWQREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A660TRG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MLINSNLKRVLESGNFAVTAELGPPTSADAEFVRKKAKILKGYIDAFNVTDGQTAVVRMA
SWAACLIGKDEGLDPIVQMTARDRNRIALQMDVLGVSALGIHNILCLTGDHMSFGNHREA
KGVWDFDSINFIKAVKQMRDEKKFQSGDEMDVAPELYIGAAANPFAPPYEFRVHRLRKKI
EAGVDFIQTQCIFNLDRFKEWMRQVQDQGLHEKVKILGGITPIKSLGAARYMKNNVPGMD
VPDNIVERMQKTPKEDRAKEGLKIAVETIHQLREIKGVAGVHIMAIEWEEAVPEIVEMAG
LHPRP
>A0A0E1SE75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei 305|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGP
>A0A522CMJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MGIPELYKEGFVISFELFPPKTEQGEINLMQALGELAVFKPGFISVTYGAGGSTQSRTLE
LSLKIRDTLGITPLVHFTCVGAGRDEIARYLGDVKAKGISNILALRGDPPKGQEHFVAPV
DGFPYANELVTFIRSINGFTIGVAGYPEKHLEAPSMEADLENLKRKVDAGADYVITQLFY
NNDDFYEFMNSVRRMGVTVPVIPGIMPVTNQANIEKVTRMCGAKIPNELMKRLVTCGSIV
DVCEVGIEYSIIQCRELKSWGVPGFHFYALNKSQAVSKVINALD
>A0A1S1V370|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 06C 126|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVQALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCETLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A1M5N8D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jatrophihabitans endophyticus|TrEMBL
MRNKTGVETLRRLLTHARYEVLPTPACEEEVREHVPPDIPITVTASPSKGLSATLELTER
LAGAGYRVVPHLAARMVSGRSELADIAARLRELGVDTVFVPAGDADPPAGDYHASLDLLR
DLPAVGTPFAHVGITGYPESHPSIVDDVVVQAMWDKRAHADHVVSNLTFDPALVQRWLRR
VRQRGITMPLLVGVPGPVDRAKLLLMATKIGVGESTKFLAKHRRTLTRLAAPGGFTGQQF
LERSATAFGAVDANVAGLHVFTFNQVAATEAWRREWLERLAAGAASRRGPRTRVLS
>A0A3B9P3V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
MKITDILANTKGCEFTFEILPPLKGQRAQEIFTNIDPLMEFKPPFIDVTYHREETVYKRL
DNGLLQEKVVRKRPGTVGICAAIMHRYDTETVPHVLCGGFSKEDTENLLIDLNFLGIENV
VALRGDQAKHESYFTPHPEGNAFAIDLVKQIKQLNQGNYLDEDLQNTTATNFCIGVAGYP
EKHFEAPSLNIDIEYLKAKVEAGADYIITQLFFDNSKYFAFVDKCREAGINVPIIPGLKP
LTTKRQLSILPQIFHVDIPDELAIQAIKCKDNAQVKQLGIEWCIQQSKELKAAGAPVLHY
YSMGKSSNINEIASAVF
>A0A7H0NQY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB00271|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A7W7A4A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas yabuuchiae|TrEMBL
MTNTILTQAEAALAHDEPLFADVGGDIAVSFEFFPPKTEKMDAQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTMDAAAHLTCVEATREEIDQVAQEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPDSVDKQADIDNLK
RKIDAGATRAITQFFFSPEAYFRFRDAAAAAGITAEIVPGILPVSNVAQTRKFAAMCGAC
IPDWMDRLFEGLDDHPAARQLVAATISAEMCRRLYAGGVKGFHFYTLNRAELAYAISHLL
GVRGKKAEAVAAA
>A0A2M7MIK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium CG_4_10_14_3_um_filter_37_18|TrEMBL
MKSFRERLGNELILFDGGTGTYLYEKGIYINRCFDELNLTNPELVTEVHCDYINAGADII
ETNTFGANSFKLTPHGLGNKVYEINLRGAKLAKTAAKESVLVAGAVGPLGVQIEPLGKLS
FDEAKDVFKEQIKGLLDGGVDLIVLETFALVKELIQAIRAVRELNADIPIVAQVTINESG
TLLSGAPLERFIEKLKDYPVDAVGLNCSVGPKAMLDALENLRSLTDIPISVQPNAGLPQN
ISGRNIYMTSPEYMAEYAKRFIQTGANIVGGCCGTNPTHIKAMRKAVQALQPVKKMDVKI
ADLQVEKPSEIKIYEKNEKSRLSNKLLKKEFVKLVELVSPKGVSPSREVDKARKLYHAGI
DAINIPDGPRASARMSALALAAIIQKEVGIETVLHIACRDRNVIGMQSDLLGAWALGLRN
ILAITGDPPKLGNYPDATAVFDVDAIGLTNIINRLNHGLDIASNPIGDPTGFCVGVGVNP
GAINLDEELKRLEWKIEAGAEFMITQPVFDIKLLEHFMKRIEKIKLPLICGIWPLVSFRN
AEFMNNEVPGASVPQKILQRMKKMTTKEEGFNEGVKIARETFDQVKTFADGVQISAPLGR
IEAIFDMIE
>A0A4Q4W0H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus sp. MC13-8B|TrEMBL
MHIQEMIADAERTGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYFGLETCMHLTCTDMGEEKVNDALARAYKAGCTNILALRGDPPREKEK
WVATEEKFQYARDLVAHIRQKYGNHFGIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGATF
IVTQMFYDADNFIRWMKKVRERGINVPILPGIMPIATYASFLRRANHMNCKIPESWMTAL
EPVKNDDAAVREVGKTLVAELCRKIMAAGIVHLHFYTMNLAQATRMVLEELDWLPTTTRP
RKQALPWKQSLGLGRREEDVRPIFWRNRNKSYVSRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKKWGEPKCIKDIATLFVRYIEKDLQTLPWSEAPLTAEADSIREDLIK
LNQRGLLTINSQPAVNGIKSSHPVHGWGPSNGYVYQKAYLELLVPPELFPEIVSRIHNHP
DLTYYAVTRTGPLKTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAYRLGKDW
AHCYDANSPSRVLIDKIMDEWYLVNIDSNGVHNASNGDTGHTNGSGAAAAT
>A0A317CNM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucothrix pacifica|TrEMBL
MYFEDEPNPGENLPILPGHVSAGRFERVLRAGQFAVTAEIAPPDSADPQEVYDRAEVFDG
YVDAINATDGSGANCHMSSVAMCALLAHKGYSMIMQVSCRDRNRIAIQGDVLGASAMGVS
NILCLSGDGVQSGDHPEAKPVFDLDCMSSLSMLKGMRDQKQFLSGRKLTKPPEVFLGAAA
NPFAPPFDYRPHRLAKKVAAGAQFVQTQYCFDIEMLENYMKKVVDMGLHEKVFILPGVGP
LASARAAEWIRSNVAGVHIPDAIIKRLAGAENQKQEGINICTDMINAIKDMQGVHGVHIM
AYRMEYAVAEIVEKSGVLGNRKPWYPTRDIA
>A0A496P3B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Riemerella sp|TrEMBL
NVTYHREEYEYVEHENGLLERRVVRKRPGTVGICAAIQNRYHIDAIPHILCGGFNREETE
NFLIDLDFLEIDNVMALRGDVMKSETYFKPEKNGNAHASELVHQIKQMNDGIYLDHNIEL
PSPTNFCIGVAGYPEKHMEAASLHQDIMNLKKKQEAGADYVVTQMFFDNQKFFEFVDKCR
EEGITIPIIPGLKPITAKSQLSMLPYRFKVDLPDDLVIEITKCKTAADIKQVGIEWCTAQ
SKELKERGVPALHYYSMGRSEGVKQIVNEVF
>A0A2U3A4Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Act143|TrEMBL
MTTLRDLLDRGTPTFSFEFFPPKTPKGERTLWEAIRRIEPLAPTFVSVTYGAGGSSRDRT
VEVTKRIATETTLRPVAHLTAVGHSVSELRHIIGQYADAGVRDVLALRGDPPGDPNAPWI
AHPDGFTHAHELVRLVKESGEFSVGVAAFPERHPRSADWESDIRHFVAKCKAGADYAVTQ
MFFHVEDYLRLRDRVTAAGCDTPIIPEIMPATDVRQIARFAELSGAAFPEELAHRLDAAR
GNPADGHRIGVEYATAMAERLLAEGAPGLHYITLNKSTAALDIHRNVLAATRVTA
>A0A1F9XPF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFOXYA2_FULL_53_38|TrEMBL
MKITERLKKPGKLFSFEFYPPKTEQDEERLFETVKDLKSLKPDFISITNSSTGATPYRTV
DLSGSIKEKLGLEVMAHLTCIGHTRVEIKAIAERLKVLGIENVLALRGDIHNIDGHKAKR
EYHYASELAADLKAMGGFAIGGAGYPEKHPDAPDFDSDIRALKTKTAAGIDFIITQLFFE
NRFYFDFMEKALKAGVSAPIIPGLMPLTSYKQLQGFDKFSVFLPQIIKDGVEKYAEDKDS
LLKFSVEYASRQAEDLLKNGAPGVHFYTLNRSKATKEILNNLEHK
>A0A175VQ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Madurella mycetomatis|TrEMBL
MGEILPSLELPVEAPKDHTMDKITDKIAALPADTNYFSLEFFPPKTAMGFSNLRDRLDRM
ARALRPLFVNVTWGAGGSTATKSLELAEICQRELGLTTCLHLTCTNMSRRMIDKALDDAK
ALGIRNILALRGDPPRRAEYRDTNEPEPEDEEEFAWAVDLVRYIRKTHGDYFCIGVAAYP
EGHADESHPLGQSLEHDLPYLVEKTQAGADFIMTQLFFDIEAYKRFEQTLRDHPSGAFKD
IVIVPGLMPIQSYQMIKRTTKLSHAKIPAPLMARLDAVKGDDEKVKEVGVDIISEIVEQI
REIKSRTKGPRGFHFYTLNLEKAVSFIVERTGLISPSTPEEEEAVITQDPLPDIKFLRVN
GSTPDQSSYGPMRRKASIGSDPRDRVIVQGRPPSYPDWEATALEASVPAEPINTRANTLA
ISEGEGVLGREATWDDFPNGRWGDARSPAYGQIDGYGVSLHVTVAQARQLWGTPRTTEDV
NNIFIRHLRGELSTIPWSEESFSPETEKIRNQLIALNSKGWWTLASQPAVNGLRSSDPTF
GWGPQNGFVFQKAFVEFFLPSADWRALERRLARPEMKDVVCFYATNAAGDFVSSDTAARA
SSADADGEPYREASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWGEWAKIYPKG
SESEKFLEKVRGDLWLVNIIHHEFVESDALWELLLT
>A0A3D1VZX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MTALNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLTNFVRKARAGADSAITQYFFNADCY
FYFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQA
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A7J9QS86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilaceae archaeon|TrEMBL
MTIRYEANPPKILPGVDIDESISKFIDKIKLISTKCDAIHLTENVLGFKRVSPITVGKII
RKEIPDLPVTVSLRVRDKTKEEIESFVAEVIQAGFSGILILMGDPPQDGQKDSGLFPSQV
VNSLKEKQVDSKIDLYLSISNKANFSKIEKKLNAKPKGFMTQVIQNIDQVKNLAENLKGY
SVIPIVLFPSDKNEKSAKFLNLNLEQFRENFPEFLSQVHQITGDVLITSPSDFSGLNEFL
EKNQV
>A0A816RSA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria magnacalcarata|TrEMBL
MEFTLGDNETVPGDCKMHAHETHLESIHNLNRLKRIESEGANIAGKICSLQSAKYVSLTE
KISKRIADNDRWFSLEFFPPRTPSGAANLIGCFDRMAAGRPLFCDITWHPAGDPAGNKET
SSMMIANTMLNYCGIDTMLHITCYGAKKAAMLEYLYKAKDCGIRSLLALRGDPHVGEEWN
PAKSDFRYALDLVKFIRKHFGDYFVICVAGYPQGHPDSTSYEDDLGYLKEKIDCGADFII
TQLFFQAETFIKFESDCRSIGIKCPIIPGILPIQGYASLRNIVRLAKLDVPKEILACIEP
IKDNDEAIRNFGVQACLDLCRTLLDSGKVNGLHFYTLNREFATIEILKKLGLWLDEQSLR
ALPWKKTSFSHARSQENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGISSAPSFGVLTDYH
LFYMKIDATRDELLDEWGRELTCEQDVWKMFACYIGGEKNSIDKVVRRFPWTDEELSAET
TLIQKSLVEFNKRGILTINSQPAVNGKSSSDPVVGWGTPNGYVYQKAYLEFFTSAENIPA
LRSVLKTFPGVNYHFVNKSGEVNETNTDDEQPIAVTWGVFAGKEIVQPTVVDPVSFMIWK
DEAFSLWTERWGKLYEPESRSHAIIEEIANTYFLVNLVDNDYPQDSCLWAILDSMFEYQK
LPKKNIES
>A0A430ZQY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSVNSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELRA
>A0A0R3B9B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas veronii|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYHPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRALLTQYKGAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1E3FHG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia contaminans|TrEMBL
MKTIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNTAAATRTICERLVM
>A0A2S7BQ68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWISKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A5F0XBD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTNKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A177DY48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria alternata|TrEMBL
MHISQKLLQAREEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDDALRDAYNAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDDVDELIDHLKEKVDAGGTF
IVTQMFYDTDLFLEWVKKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTRCNIPKHWTEAL
EPVKNDDVEVREVGKHLVAEMCRKLIDAGITHLHFYTMNLAQATRMVLEELDLLPDPESP
LEKPLPWRPSLALNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPMSIRDLSELFVRYMEGKLESLPWSEQPITTEAGSIQDDLIN
LNRRGFLTINSQPAVNGAKSSDPVFGWGPRNGYVYQKAYLEVFVSPEHISEIITRLERDP
EFTYYAVNKDGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDVVDTWYLLNIVHNDFHATRGIFPIFDGLEVKDMDKPLVNPSVDL
PSANGDEATKVVNGGSHTNGTNGEQAEPHKEENPSLIDAAKAAAVEVTNGMRSLAMSN
>A0A2K8TW36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYAEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A109FS46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A174W3Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides distasonis|TrEMBL
MKVIDLIRDSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIVHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A2V9NMB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPGKLLDRLKESPVLCDGAMGTLLYGQGIFINRCYDELNTLQPDLIRSLHHQYLQSGAEI
IETNTFGGNRFRLERHSLGDKVKDINLTGARLAREAAKSFDAWVAGSVGPLGIRIEPLGK
TSFEEARETFREQISALVEGGVDLLILETFGYIEELHQAMMAAREVDANLPIVAQVTIDE
DGNCLDGSTPETFTPRLEEWGAHVIGCNCSVGPVAMLDAIERVRACTSLPLSALPNAGIP
RSVEGRNIYLCSPEYMASYARKFVAAGVRLVGGCCGTTPEHTRAMKSALRVGEARARSAS
VQVATVSTPAAVPAVPLQERSVLGKKIASGEFVTMVEIVPPKGTDISKELEGARFLKSVG
VDAINIPDSPRASARMSNQALSLLVQQQVGIEAVLHYTCRDRNVLGIQSDLLGAAATGIR
NLICITGDPPKMGNYPDATAVFDVDAIGLVNIVHNLNRGRDIGGNPIGIGTGFLIGVGAN
PGLPMLDEEIRRFEYKVQAGAEYAVTQPVFDLNLLENFLRRIEHCRIPVVAGIWPLVSLR
NAEFMKNELRVSVPDSILRRIANAKTPEGAREEGIQVAREMLIAVHGITQGAQISAPLGR
YGSAIDVLEALGTAAADR
>A0A0C4UT24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria subulata|TrEMBL
AYGIHLGTEMCKKILAHGIKTLHLYTLNLEKSALAILANLGLIDMTKIKRPLPWRPPANV
>A0A1Q9I377|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8G6GNG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVPPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVAPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A6N8V4T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MADLREMLSGGRVHVMDGAMGTMLYARGVFFNVCYDELNATHPDLVEDVHEQYIRAGADI
IETNTFGANPVKLSSHGLDARTEELNERAAAIAVRAASGRAAVAGAVGPLGIRLEPLGPT
SLEEARDYFGRQVDGLLAGGVDGFILETFSDLVELEQAFRAVRSRCDFPVIAQVTVGEDG
VTAYGTTVEQAARAAEAWGAEAVGLNCSVGPAVILEGLEAMAQVTRLPLAAVPNAGLPRA
IGDRKIYVTEPEYMAQYARPAIDAGARIVGGCCGTTPEHIRGIAEVVATIQPQSTSVRVI
RSVGESSARKTPPPLASRSELGRRLAAGEFVTMARVLPPRGWDTARMLDDCGALAQAGAD
VIGIHEDRRTARLSVLALAGLIARSCPAEPLAHYTCRDRTLFGMISDLLGTAASGVRNVL
LLTGDPPGAAPYSDFRSVVDVDSIGLTNVVTAMNSGVDPSGNDIGPPPGFVVGVALRQGT
RDPARELGRFHWKVDAGAHFAVTQPVFDADHLVEFLAGVGNGGGGPGIPVVAAIQPLGSL
RHADFLKNEVPGVVLPDRVLERMRRAESRSADHAAAEGIAIARETAAALAGEVAGLEVAA
HRGPGLGAAVAVLEGLAVV
>A0A151G3E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHADHPVYILGTIGGLAGDTDATVQR
ATPATIAANVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFVGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A1K0H766|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ustilago bromivora|TrEMBL
MANGIESPAIPPKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMAD
LGPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKQFG
CRNILALRGDPPAGQSEWEPHAAGFTRAKELVEYIREQYGDYFAIAVAAFPEGHPEAIHG
PGKELERLKEKIDAGADFIFTQMFYDFDIFAKWVKEVRAAGINCPIIPGVMPIQTYGGFQ
RATARFGTLVPQYFHDALDPVKDDDQKVRDIGTRLVGEMCKKIVGSGLGISGLHIYTMNL
EKGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRRDEKIRPIFWANRAKSYVNRTETWDEF
PNGRWGDARSPAYGDVDAYGVKLRYSNEEAKQMWGNPTSLEDVKALFQKFCAGQVKALPW
SETPVARETSVISDKLTKMNELGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEF
FVSPEHLDALIARIEADPQITYHAVNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVE
SISFLAWKDEAYEIGRNWAKVYEPSSPSRKYLEEMFKRYFLVNVVHNDFKAADAIFEPFL
NAAKTAAVNGSLSSIGSLSSIGSTVADAAGRVSNSISSLANGLSNGHTAAPAPAA
>A0A031WFI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridioides difficile|TrEMBL
MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAANVTDFQSAVMRATSLA
TCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLLALTGDHTSVGDHPQAKGV
FDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTPEYSPIEVQLLKMKKKIKAGA
KFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSPGMAKFMTANVPGIFVPDEQIER
LRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIMAIGAEENIPAILDAAGL
>A0A0A7V0Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosopelagicus brevis|TrEMBL
MTIRYEINPPKVSDPPSRIELLDERIEQISKFCDGIHVTDSVLGIERISPLLIGAEIKQK
HPKLNVTISLRVIDKTISEITDIVDSAINANIDGILILMGDPSPENDYKSGVIPSFAVKH
LIQNGFNEKINLFLSLPSKPNFEKISKKVESKPNGFVTQVVHDISQVKRLHDYLNPKNFE
IIPCLLFPSQKNSRSAQFLNLDWSNYEDNFSSFVLEIESITGDVLLTSPNDFKGALDFLT
RLQN
>A0A3R6FJ22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHAHATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVMKCKTDDDAKQLGIEWTTAQVQDLFEHGYNNVH
FFTVSAVDSVKQIAKILF
>A0A165B5L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis|TrEMBL
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTRAKEFIS
VHHERTEPGLDEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMAHAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>A0A7W6SDP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium cellulosilyticum|TrEMBL
MAILNLFKNRRADEKAERASFGALLDGYSIEVMPRTAAKIDNFREFLPAGMRVYIAHIDG
TPIEDMVATAKRLTEDGYAVMPHVPARLIRDKATLEDWISRYVNDAGVTQALLLAGGLNV
PRGDLESSLQLLETGLFGRYGFKRLHIAGHPEGNRDIDKDGTTRLVDRALKFKQAYSENS
DAEMAIVTQFAFDAGSITRWVERIADAGVTLPIHLGVAGPTKLQTLIKFAISCGIGPSLS
VLQRRAMDLSKLLVPYEPDEFLTEIANYKATHPQSLIDEIHVFPLGGIRASADWVNERVL
KGKVASQ
>A0A0K8QJS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mizugakiibacter sediminis|TrEMBL
MNSTSYSPPPTPISFEFFPPKTDEQRAQLDRTAAKLRAHAPEYVSVTFGAGGSTLSYTPE
TVQRLRDVHGMEAAPHLSCVGGTRAELGALLERYKAMGCRRIVALRGDLPSGMARSGDFH
YASELVAFIRAEHDGWFHIEVGCYPECHPQAEHAQADLAHFKAKIDAGADGAITQYFFNA
DAYFRFVDAARRIGVAVPIVPGIMPIANFAQLRRFSEQCGAEIPRWIAKSMAAFADDAEA
IREFGADVVAAMCRRLVEGGAPALHFYTLNLAKPTQAVLARLA
>W2P2L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora parasitica|TrEMBL
MGKIIESIRSAYAARADDASARPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGAERWSPVEGGLSNAVDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIQWISDCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPEKVLTALDAIKNDDAAVRRYGTQLAVETCRRLLAAGVNSLHFYTMNLATT
VTQVLEGLQLLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRTELWGTPQTEEDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAAIRENLQWLNSNGFLTINSQPRVNGAPSSDPSVGWGGDDGVVFQKAYVEFFVA
PEKIAHLVKVMRRDYPQLSFHALNRRGDEHRNTPLHSVTAVTWGVFPGIEIVQPTVVDSD
SFAAWKDEAFELWQTQWASAYPEGSCSREVIQHIYDSYFLVNIVDNDYANDDSDIFSIFT
RIITEAMDKEELRTRVLELEARREKMFDTLASFQSLQKDLNGELRAAHSELAGVRGENLQ
LKEKVRQLEAQLALASL
>A0A2X2NYJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus agalactiae|TrEMBL
MSKFLEKLKTDILVADGAMGTLLYTYGLDTCHESYNVTHPEKVLAIHQAYIEAGADVIQT
NTYGAQRHRLKNYGLEDQVVSINQAAVNLAHQATLGKETFILGTVGGFRSQRQCDLTLDN
IVEETLEQIEALLATGQLDGLLFETYYDIEEITTVLKIVREMTDLPIITNISLHEAGVTS
NGKPIVEALSQLVMLGADVIGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASQLSLDGE
NSQYQFSQNSEYFGKSAELLVAEGVRLIGGCCGTTPDHIRAVKRSIRGLKPIERKVVTPI
IPVKDFVRRIRRTDTLVDKVKKEVTIIAELDPPKHLDIVQFQKAIRAIDQKGIAAITLAD
NSLSNTRICNLSIASLLKDEISTPFLLHIACRDHNLIGLQSRLLGMELLGFNHILAITGD
PTKLGDFPGATSVYDVTSFKLLSLIKQLNQGLSYSGASLRRPTDFTVAAAFNPNVKNLTR
TVKLIEKKVASGADYFMTQPIFDHSVLKELADLTKTVEQPFFIGIMPITSYNNAVFLHNE
VPGIKLSESFLSALEKVKDDKEACLTLALNESKSLIDEALNYFNGIYLITPFLRYDLTLE
LIDYIQKKQVRKSS
>A0A090TCR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio maritimus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSTPTMEETLWKSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKSETGLVAAPHLTCIDASRDELIDIAEDYWANGIKNIVALRGD
IPEGGGQPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFKQASRFAAMNKVKVPGWMQKQFE
GLDDDLMTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPEA
>A0A1V4SRN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium thermobutyricum DSM 4928|TrEMBL
MRIRDLFNEKKLVFSFEVFPPKNTSPVKSIYNALNELSELNPDFISVTYGAGGTSVNNKT
TEISSLIKNVYKIEALAHLTSMGAKKENIDFIKERLALEGVENILALRGDKKEECNSGDF
LYASNLMNHLREDFNIIGACYPEGHIENKSIDLEIDNMKRKEENGCSSFISQLFFSNETY
YEFLEKARNSGVKAPIQAGIMPVINKKQIQRIGNLCGAYIPLKFKKIMNRYEYNPEALRE
AGIAYAVEQIIDLSSSSVDGIHLYTMNNPYVAKKIKENIKTVLKAVNE
>A0A8H4HCR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus fumigatiaffinis|TrEMBL
MHVKDMLTDNESAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVNAALSTAYKAGCTNILALRGDPPRDKEA
WEATEGGLRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
VITQMFYDTDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEAL
EPVKNDDAAVKEIGKRLIADMCRRLLAAGIKHLHFYTMNLAQATQAVLEELRLIPSEETP
LQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSIRDVTQIFVRYLEGKLDRLPWSDSPISGEANAIKDNLVQ
LNSRGLLTVNSQPAVNGVRSSHPVYGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNP
DLTYHAVAKNRELRTNTRDSPNALTWGIFAGREIVQPTIVETISFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQDIMDNWYLVNIVNNDFHNTYDLFDLFNGLEVKDLDLEVGPDTVETK
SQPNGAAPEVLAVKN
>A0A248UH18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ochrobactrum] quorumnocens|TrEMBL
MGFYGLSRRSDIGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLKPKFVSVTYGAGGSTR
ERTIRTVARILKETDVDAAAHLTCVDATKEEVDEVVREFASLGVKRFVALRGDPAAGIGE
KYVSTPGGYQSSAELVSGLRQIDDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNELFERYVERVRRAGIYIPIVPGVLPIHNFKQVKNFCARSATHIPTWLAERFE
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPNTETAL
EVA
>A0A413MCR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] rectale|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNQYNVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKETTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>A0A2E3Z9S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MTVLSSILEDPQKFACGVELVTTRGTMGETKAVRTRSFAGDLAEDPRVDWVSITDNAGGN
PHLAPESLGKPILYAGKEVVIHLSCKDFNRNGLESTAWHLSSEGFRNILALSGDYPTAGY
SGMSKPVFDIDSIGLLTLLNEMNHGLGVPLRNGDGETKKSLQQTQFYLGAVVTNFKRHEN
EVIPQLLKLRKKIECGAKFVIAQIGFDSRKSSELIGYMQNHGLAGIPLIGNVFVMSAPLA
RFFHRGTIPGVYISEELLEKFIHMGKSPDQGRKFFLEFAAKQVAVFKGLGFRGAYIGGVD
HAKDLDEILETANSFAEEDWKAFAAEIQFPHAEEFYLYEQDPTSGLADCSRLNSTYAKSL
ETREPTHNVTLGYRFNKLVHDRVFTPGNRLFSLGKKIYESSADPSQGPKPLRILENVAKS
TLFGCQDCGDCSLPETGYLCPESACVKNQRNGPCGGTRDGLCEIEDFECIWARTYDRLKA
EGKEQEMLSHTPVIQDQSLRGTSSWGNTFRGIDHIGQNPQRKKDMD
>A0A523ZL90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MGEAYSELMKQIKAGKFVFTGELEPVKSTNLQKVIEGAKILKGHVVAINITDNPTAFGYM
NALVPSYLIQKEAGVEAVYQMTTRDRNRLALISDVLAAGALGIKNILALTGDHTTVGDTP
QAKPVFDLDSATFVYMLRKMIDEGVDLNNNKIENPPKFNIGIAAAPNADPLEPEILKIER
KVKIGVDFIQTQCVYSVEQAKNFLDAASHLNTPILLGIAPFKSVGMMKWMVEFVPGIKVP
EEIQDRIRKAKERGGKEAIFAENIEIFSQMIREIRKTTNAAGLHMMAVGFEWIVPKIIEH
TGLK
>A0A412QV02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus|TrEMBL
MGIAELINKERKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKDGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVEAGADYVVTQMFYDNRKYVDFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAMKCKDDKEARALGIEWCINQCRELIAYGVPGIHF
YTVGAVDNVKEVATAVY
>A0A0X8FAU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aerococcus sanguinicola|TrEMBL
MKTKELFKEKTVFSYEVFPPKKTSGPQSIYKTLEELKSLSPDCISVTYGAGGGDNNDESF
KIAQTIKGYGIESIAHLPCIGMTKADLEEKLEELQALQVENILALRGDLPADDYAPGDFS
YASDMVRFIKDKGDFNVVAACYPEGHIDCKDKVQDIKHLKTKVDAGVDQLITQLFLDNND
FYAFRERCELADINVPIEAGIMPVVNKRQIERMTSLCGVKLPDKFVKMMDRYQDKPVAMR
DAGIAYAVNQIVDLISQGVDGIHLYTMNNPYIAKKIHEAVHNLL
>A0A5F0K5U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas taiwanensis|TrEMBL
MGFHSARQVEALNQSLADLGGDISVSFEFFPPNSEGMENTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLEHDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQA
>A0A3M6H6G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas caricapapayae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRSLLTHYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFT
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A8D8MU53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Culex pipiens|TrEMBL
LSRGSVSFGRLSFARNLSADVLVWWLSSSRDLLRTARGTRVTVEKRTEKRLRGLNLSSPS
REKRRPPPTSPMHRQTVESDPNGEEDKSTILAAGAVTAEVMHSHENSRNLKQVIQRWTTS
ERLCYSIELIPREDFHLDLGRLAPVFCSLPWISDNNLQYQRFVDTPMLKMTAKIVPRCPV
MNHLSCYNITETQVDKFVDMGNWNLFVIRGDTVSEGQRFQHSGDLVEYLRAKNNPDLTIG
VGGYPYGHPESPSVDYDVKYLKQKVDLGVDFIVTQTLYDAASFLAYVDECRRSGITVPIV
PGLFLPGSPDQLETVLALTRVNPPAGVRDLLQSHAHDEPDQFEAFVVKHFAELIRTLRRE
RPDEVRLVHFFTFNRLDLLKKVLDAIADLL
>A0A534DH98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAAILWDSIERLAPLGPRFVSVTYGADGSTRERTHELVTRIQRDTALTGAPHLTCIGASR
GEILAIARGYWSQGIRHLVALRGDPPQGESPHRPHAADFRYAVELVAALAALAPFDISVA
AYPEVHPEARSAAADLDNLKRKIDAGATRAITQFFYDTSVFLRFRDALAAAGVHAPLVPG
ILPITRFPQVRRFAERCGASIPRWLHERFAGLDDDPDTCRLLAASVAIEQVEALRRHGVR
DFHFYTLNRAALTYAICHALGLRPVARAAGAARQEALG
>A0A0Z8F4P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A2N7W0U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia rhynchosiae|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLALLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHLSCIGSSKESLRAILNQYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCKRLIDANVPGLHFYTLNGAAATKAICERLNG
>A0A0E9GLJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A4J1T2W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQYMQELTPYFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCDNIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>R9I0T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola sartorii|TrEMBL
MRVVDLIKSTDKTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPETNGYNHAIELESQINDFNKGVFVDGSPIKITGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLSMIPKTFKIDLPQELAVEAMKCQTDEEAAALGIEWCIHQCRELIGYGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A7Y4W844|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sideroxydans sp|TrEMBL
MANLIPISFEFFPPQTAEGVEKLTAARQRLATLKPEFFSCTFGAGGSTQDRTLDTIKLIH
AEGHQAAPHLSCVGGTRDNIAALLKTYQEMGIKRIVALRGDLPSGMASIGEFHYANELVS
FIRAQTGEHFHIEVAAYPEFHPQANSAREDMLNFKRKIEAGANSAITQYFYNADAYFRFV
NEMHRLGITAPIVPGIMPIVRYSQLARFSDMCGAEIPRWMRKTMEGYGDDVESVQAFGRD
VVTQLCEKLIAGGAPALHFYTLNQANASIEILNRLGYRA
>A0A477WGU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVEDVDSGERLLDKVKERLTILVELDPPRTFDTTKFFEGAQALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKAKIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDDVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A450XSM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. MB|TrEMBL
MNAQGSNTTFSFEFFPPKTPEGKNNLRATWQHLSKLNPHFFSVTFGAGGSTQSGTQETVL
EIQQDSGIDAAPHLSCIGSSQVKIRQILDDYSSHGVQRIVALRGDFPSDMKDPGEFRHAN
ELVEFIRAETGNYFHIEVAAYPEFHPTAPSARVDFENFKRKVNAGANSAITQYFYNPDAY
LRFMDSCERLGVDIPIVPGIMPITNYTSLAGFSQRCGAEIPRWLDWRLQEFGEDTNGLKA
FGIDVVTELCQRLLEAGAPGLHFYVLNRVEPAMTIWKNLGLPGAGNSPD
>A0A2X0PJY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQIFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNLIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTF
>A0A1X7KI46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium psychroaquaticum|TrEMBL
MKIVDHIKNAKGKTSFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYLYKQ
HDSGLLERVAYRKRPGTVAICAAIMSKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTPGGHAFATDLLQQVVDMNEGKYLHEDIESSAKTDFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFYNVDKYKEFVTKCRDNDIHVPIIPGLK
PLTTKKQLIALPKIFHLDIPEELSEAVESCKTNADVRQVGEDWLVQQCKELIEFGAPVLH
FYTMSNPGPTKKIVERLA
>A0A837Q8U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHDFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEHFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAEHDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVK
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTDILKEKLIPTVPLETRGTSSWKNWYLATEA
>U3CLG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callithrix jacchus|TrEMBL
MVNEARGNGSLNPCLEGNASSGSESSKDSSRCSTPGLDPDRHERLREKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCHQRLEEITGHLHKAKQLGLKNILALRGDPTGDQWEEEEGGFNHAVDLVK
HIRSEFGDYFDICVAGYPKGHPDAESFEADVKHLKEKVSAGADFVITQLFFEADTFFHFV
KACTDVGITCPILPGIFPIQGYHSLRQLVKLSKLELPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCRELLASGLVPGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKNYYLFYLKSKSPREELLKM
WGEELPSEESVFEVFVHYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGVL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYE
EGSPSRAIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNEREAETP
>A0A7Z0E5A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGVSIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGINEFHLYTMNRAPLVSAVLDNLGFSRRAAKSAGAAA
>A0A0N1CH19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides immunogenum|TrEMBL
MTTNPLDRDGPVAELQDPGSIADRLAAVQPGEVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAANTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAPWVPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQASDLD
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPTALEERLLKAAGDGPDENRDEVRKVGVEVTTAMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A6H2UUX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKTLEELWSSLWQVT
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLAIEA
>J7EPU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nicotiana tabacum|TrEMBL
MKVIEKIQEAAKDENRVVFSFEFFPPKTEDGVENLFERMERMVAHNPSFCDITWGAGGST
ADLTLEISKRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKINGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDVIPANGIATQEIYENDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPEEIMAALEPIKDSEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKSALSILMN
LGLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTLGWDEYPHGRWGNAQN
PSYGALSDYQFMRARSRDKKLQEEWVVALNSVEDTYEKFKDYCLGKLRSCPWSELDGLQP
ETKIINEKLGHVNTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSGEKL
NTLVEKCKAFPYLTYMAVNKEGNWISNISQTDVNAVTWGVFPAKEIVQPTVVDPASFMVW
KDEAFEIWSRGWAQLYPETDPSRKLLEQVQNSYYLVSLVDNDYINGDLFSIFQDI
>A0A1T5U446|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus subsp. massiliense|TrEMBL
MTTNPLDRDGPVAELQDPGSIADRLTAVQPGEIAFSVEFMPPRDEAAEARLWRAARVFER
YRPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEERLLRAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTARG
>A0A349Q2A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTQHIENAKGKPLFSFEIVPPQKGSNIKDLYENIDPLMEFKPPFIDVTTSREEYVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGIDAIPHVLCGGFTKEETEYLLVDCHYLGIDNL
VALRGDPMKGEKYFEPTKGGNTYAIDLVKQIKAMNAGQFLHEKLPVQNAPDFCIGVAGYP
EKHIEAPSLEADLKRLKEKVEAGADYIVTQMFFDNQRYFKFVEAARAIGINVPIIPGIKP
VAVKRHLQMLPQVFWLDMPQDLIHAIEQAKDNATVRQIGVEFAVQQSKELIEFGVPFVHY
YSMGKSDNIYNIAKKVF
>A0A2I1U1G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A094XK99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus alcalophilus ATCC 27647 = CGMCC 1.3604|TrEMBL
MNLIEKLQNNLLVGDGAMGTLLYEQGIDQCFEEINLLHPEKIKAVHQAYIDAGANVIQTN
TYAANRLKLEKYGLEDKVRALNKAGVQIASEVANEEIYILGTVGGIRRYKNEEWTLAEIK
SAFFEQMTELLKEGVDGLLLETFYDLEEALMATQLARKLTDQVLVVNVSVGEVGVMQGGV
PLEKAFQQLIEAGANVVGLNCRMGPFHMLKSIETVSLPKGAYLAVYPNASLPDFRDGRYY
YQSNSDYFADMGERFIEQGVRLIGGCCGTTPEQIKAFAEVAKVNKPVNEKKVKSILKVDS
RQNQARPKRETLPDIVKKRSSIIVELDPPKRLSIEKFMNGAKALTDAGVDAVTLADNSLA
SPRVDNMALGSLMKAQYSTRPLVHVTCRDRNLIGLQSHLMGLHALGIQDLLAITGDPTKI
GDFPGATSVYDMTSFQLISMIKQLNEGLSFSGKDLGQKANFSVGAAFNPNVRHLEKAVAR
MEKKVESGADYFMTQPIYNEKQIEELAKLTKHIEQPIYIGIMPLTGSRNAEFLHNEVPGI
KLTDSIRETMKKCEHDKEQSVQEGLTIAKSLIDATLDHFNGIYLITPFLRYEMSVELTQY
IQEKQQQKEITLQ
>A0A8H7L2G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Athelia sp. TMB|TrEMBL
MKITKKIEAASKADRVWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLTSEMVKTCQSIIGIETCMHLTCTNMPKEKVDIALKEAKQHGCRNILALRGDPPQGKEE
WESVAGGFVHGIDLVRHIREHYGDYFDIAVAGFPQQQLLPPAELAQELAWLKEKVDAGVN
FIFTQMFYDVEVFLDWVKSVRAAGITIPIVPGIAPIQTWNGFQRATSLAKTVIPKSFSDA
LEPYKNDDEKVRAIGIKLVADMCRRILDADIGIKGLHFYTMNLEKATRLLLEELNLVPRV
ETIKPLPWRQSLTPNRREESIRPIFWANRAKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEEGFKLWGEPTTFDEIKMLFSRFCTKHLSALPWSDQAPATETSVISQQLA
KMNEYGFLTINSQPAVNGARSDNKVHGWGPSNGYVYQKAYLEFFVSPELLESLLVHIERD
PSITYYVLNKSGDLRTNTHSEGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAYELGQQ
WAQLYDAGSPSRKLICNLMETMLLVNVVHNDFQSSDAIFEPFFKAGAEFAARKSPVINGT
TVNGHAD
>A0A090IDF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moritella viscosa|TrEMBL
MKYSIELVPRTWETLNTEVEEVSQFSQINTLNIPDLLRFDVRSWDACDRLQDKFDEVIPH
LRAIDFDLRNGFPLTDFFRHSKINSVLVVEGDPPQDISHRTYRNTSCELIRIIKKELPYM
KVYAAIDQYRTSMRKELDYIHDKIDAGVDGFFTQPFFDLKFLDLYMDMLQDTEVFWGMSP
IHSETSKSYWENKNDVVFPSDFEATKEWNINFGRAMIKKVQAKNDNVYFMPIRANASEYL
SKLLAED
>A0A6N4QYW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira yasudae|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTPEGDVKLMETVKELSRLNPDFVTVTYGAGGSTRDK
TVQILSEISKNYSVPTVSHFTCVGANRDQIRETLKGIRSAGIVNLMALRGDPPKGEGEFK
KTEGGFANATELISFIRSEKMDFCIGGGCYPEKHPNAKTLEEDVRNLKLKVEAGTDFLVS
QLFFVNSIFENFLNLVRKVGITIPVIPGIMPITSFSQIERFRSLAACEFPSSLIEDLQEV
EHRPEEFYRRSLNFTVKQCRELLAMGAPGIHLYTLNQSHASYDIVRELKG
>A0A5F1YEX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira gomenensis|TrEMBL
MKRISEIYGSAKGPVYSFEFFPPKTPEGDTKLMETVQELSSLHPDFVSVTYGAGGSTQEK
TAEIVSLIGKNHSIPAVSHFTCVGADQSKILESLKRIRSEGIQNLMALRGDPPRGQGEFK
KTPGGFANATELISFIRSENLDFCIGGGCYPEKHPDAKTLEDDVRHLKLKVEAGTDFLVS
QLFFVNSTFEKFLNLVRKVGIGVPVIPGIMPITSFSQIERFRSIAGCEFPSSLIRDLQEV
EHRPEEFYRRSLNFTVNQCRELLDMGAPGIHLFTLNQSHASYDIVRELKGGSL
>A0A496ZHI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTKTPSRLEKILSAGHMAVTSECGPPRGSDPEAIIKKAEMIKDHVDAVNITDNQTSVTR
MCSLAACIRLKLMGLDPVLQMVTRDRNRIALQSDILGAASFDIANILCLSGDHQSFGDCA
QGQNVHDLDSMQLVQTVRQMRDDGKFLGGDDIKRAPQMFVGAAANPFADPFEIRVPRLAK
KIKAGAEFIQTQCIYNLDKFEEWMKLARDRGLHEQVYILAGMTPMKSAGMAKYMKNRVPG
MDVPDTLVKRLADTPKEKQAEEGIKICIEDIQRLKEVEGVSGFHIMAIEWEEKVPEIVEK
TGLYPRPQIQE
>A0A0B1IZR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEIYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A432KFB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIKDILTKTRPISFEFFPPRSAEGIPAVLETMDELKAYCPDFVSVTYGAGGSTRAFTEE
ITLQIKNETGVEVMAHLTCVGQNKEEIDEVLQRLESEGVDNLIALRGDPPKGTTEFVPVE
GGFQHATDLLKYVKSNFKFGVAAACYPEGHTESVDLDTDLKYVKMKVDEGADFLVTQLFY
DNRYYFDFVERARAGGIDVPIIPGILPVLNSAQVRRFTALSGSEIPPDLDKLLDKYAESD
NSARDMGVEYATAQVRELWDSGVPGVHFYVLNRSYSVSRILDNLTISGHQRQD
>A0A3D5YDM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MQTLKESLSSKKFTITAEICPPKGTDTSDFLKKAQLLKGKIAAANVTDNQRAVMRLSSLA
CSVILLKEGIDPVFQMTCRDRNRIALQSDIMGASVLGIKNILALSGDHVSFGDHREAKPV
FDLDSVQLVQVIDKLNKGTNMKDMPLKGGTDFFIGAVVAPEADPVEPEMIKFEKKVEAGA
RFFQTQAIYNMEKFHRFYEYAKRFGVKILGGILLLKSAKMANFLNTNVPGVKVPKHLIDE
LEKAQDQLEKGIEIAARQVNELRSFCDGAHIMAIGQEESVVRIIEGAVL
>A0A536MG52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLGRSKPTISFEFMAPRDESEVEVLERTVATLAGHAPDWVSVTYRVRTGEKTLEL
VTRIKRHYHIEAMAHLTCANSADRTRQILNWMEREGVANVLALRGDPPISGEPFTPVDPQ
LTHGSDLVSLVRRSGYRFGIGAACSAEKHPESPDVEHEFRYMKLKVEAGADFLITQLFFD
NRFYFNLVSRARAAGIGVPIVPGLMPVPSRRSLGVMTAMSGATVPAELQSAIDNAADDDA
VRALGVQHCIAQCAELIEARVPGLHFYTFNRARAPIEILAALRGQQLLAS
>A0A2E9A4Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNSFSKKLSQNQFIVTTELNPPKGTELEPLISKALTLRNHIDAFNLTDSHSARMSMAPIA
AAHKLKLNNIEPILQVACRDKNRISLQGDLLAANALGIQNILCMTGDNPKAGDHPDAKGV
FDIDAVSLINAATRLNSGYDLSDSKLAGSPSFCVGAVVNPSAQDLDAEIARLEQKIDSGA
VFFQTQGIYDVKQFQNFMQRIEHTNAKIIAGVMILKSAKMARFFNKNLFGVSIPNQIIKQ
LDSSKNNRQATTKITTKIIQEIKDSCHGIHIMALGWEDLIPQIISESNVKS
>A0A718QVP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium (strain SL1344)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A376NXY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPSL
>A0A6D0IGA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
G
>A0A1X0ZAT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALLIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQPTPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEDRIEHWQNQVHTLEQWAPA
WQASWQMPGLPAVIFHPPQAAWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRRPLWATHLGAQVLHKVERAVKRPLVGCDTCGRCRLEDTLYVCPESCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFQAATP
RRLSPQPAPRSQPES
>A0A4Q5HBJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides intestinalis|TrEMBL
MRIIDLIQSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNRYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELACEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A5R8R556|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas edaphica|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITQMCEQLLQGGAPGLHFYTLNQTEPSLAIWNNLKLPR
>A0A139B476|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudocatenulatum|TrEMBL
MHSPMFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVS
EYGIPSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFEHASDLAV
YIRQQRPDMKIYGACYPEKHPQSATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KARAAGIDVPIEAGIMPVMNAKSVLNMSNKCQSKVPEKLGIMLDKWGGDKALLKEAGIAY
ASEQICELVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A099CTM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oleiagrimonas soli|TrEMBL
MTVISLEFFPPKTDKQRAQFEQALPQLRSLDPEYASVTFGAGGSTLSYTPQTVKALMDAG
LDSAPHLSCMGGTREEIAALLDDYKAMGCRRLVALRGDMPSGMAGPGDFSYASELVAFIR
EHAGDHFHIEVACYPETHPQADDALADLRHFKHKVECGANGAITQYFFNPDAYFHFVDDA
RKAGIDVPIVPGIMPISNFTQLKRFSDTCGAEIPRWIAKRMQAYGDDVDSVRELGADIVA
GLCRRLLEGGAPGLHMYTLNRAVATMAVVERLR
>A0A1F2P3L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Syntrophoarchaeum butanivorans|TrEMBL
MGEAFSELMKKIKAGEFVYTGELEPHNLSTDISDVVEWAKTLKSIGKIVAANVTDNPQSF
SAMTSLAASFIIQRDSGLEMIYQLRTADKNRLALASDILAASALGLRNILALTGDHTHMG
NTPDAKPVFDLDSAQLVDLIHHMVYEGVDLAGNEVQGPRPQINIGVAGNPNQEPLEIEVL
KMERKVEVGADFIQTQVVFDLDIALTYLDAIEHLNTPTLIGIFPPRSYGQAEFFDKFVSG
VTVPPEFLEAFKKFKQISDKAERKKKIDEFNIEYFIDFIKEIKKKKNCAGCHIMAVGYPD
VIAPIIEGVEK
>A0A8B5GN42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria rhizophila|TrEMBL
MPVTPPTARAEDRPQLVAAARTTDEPAPTSGAHPAGSAAPASPTSSTGEHDPARASHPRG
VPTAATCRAGAPAAPPPSPDSSEPSCAEPPARTSWLVRRPRRSTLVSFEVFPPRPTADPD
TVWRSIDAMAQAGPDFFSVTHGHSGGRGVSREALRHLRRTTRTPVMAHFTCGGTDRAGLE
RSVEQLLDDGVRDLLALRGDPPLGAGQWRTPPGGIGRASELVRLIRDVERRRFGDGFRPG
TRPLSVSVACYPSPARGRDPEADLASLWEKQEAGADYAITQVLYEPEDYASFLERARSEG
IHIPVVAGLMPLTNPKRLQRMTEITGVPVPERLTRFLTSGSPEELRHRGTAATLSLIDDL
LDLGCAGFHLYTFNRPDAALTILEHLRVRDAAREYRGRSPAA
>A0A6J6LE94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSIFSRLKKSSTDVSPAVKTLVSSMRYELIPMKSIEQAILDLPSGAPVSVTCSPVKGISA
TQEISARLIASGHEVVPHFAARLVESREHVQKLATWVREQGIKEVFLIAGDAEKPAGPYT
DGIELLRDFLDSNSGVSRVGFGSYPDGHAFISREALSTALYDKQKLLEEAGVQGLASTQM
CFDVAQIRQWIKTERDNGFSVPIQLGVPGVVDRTRLMSLGVRVGVGASMRYLSKNKASIM
KMLSPGGYDPTELVAGLAKDSQSLNIVGLHSFTFNSVADTAAWQREILATK
>A0A334NJB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter nosocomialis|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRLEFAGYPAAITLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KKAKSFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELNVLEELWNSLWQVT
TGKEFSPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGFGRFIFKAFFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEVLKEKLIPTVPLETRGTSSWKNWYLGAEA
>A0A6J7SXD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSADTAPTISFEFFPAKDEAAEANLWNAIADLQQYQPDFVSMTYGAGGGTRDRTVRIASE
FIARTGVPVIGHLTCVGSTRDELKEILEQYKSEGFHGVLALRGDPVGGPTAPWVTTPGGF
DFADQLVALAADVGGFSIGVAAFPDVHPASDGNFVQDVNVLLRKEELGATFAITQFVFDS
GRYEALRNALDQRGSKLSIYPGIMPVTSYPQIVKMLELSGGYMPKATRLRFARYQNDAVS
LKKLGIDVAVQICEDVFALGAEGLHFYTLNNAGPTGEIIKQLSMLSR
>A0A1R1S0N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus swezeyi|TrEMBL
MGLFEDIKSKILIADGAMGTLLYSYGIDRCFEELNISKPDEVKRIHEAYVQAGADIIQTN
TYGANFIKLSRYGLEDETKQINEKAVRIARSAAGSAHVLGTLGGIRTFNKNAYSLEDIKR
SFREQLYLLLNEQPDGLLLETYYDLEEAREVLKIARKETELPIILNVSMHEEGVLQDGTP
LSEGLKLLADLGADVVGINCRLGPYHMINALEEVPLLEDAYLSVYPNSSLPSLVEGRLVY
ETDDQYFRDSAMEFRNQGARIIGGCCGTTPNHIRAMAEAVKGLPPVTEKHVKTRKKAAAA
VRHERTEPALDELAKEKRSIIVELDPPKQLNFEKFLRAAQELKSAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLSDVLAITGDPSKIGD
FPGATSVYDLTSFDLISLIKQFNEGLSYSGKPLGKKTNFSVAAAFNPNVRHIDKAVKRIE
KKIDCGADYFISQPVYSEEQLIKIHEETKHLKTPIYIGVMPLTSSRNAEFIHNEIPGIKL
SDAIREKMALAGNDKQKQTEEGLTIARSLLDTACDLFNGIYLITPFLRSDLTAELTAYIH
KKEKETTNA
>A0A6J7J1Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTRIADLLRAGRTLSFEFFPPKTDEAALALRTTIAELDELHPSFVSVTYGAGGSTRERTR
DVVIAIEREVGLAAMAHLTCVAHTRSQLDSLLDEYHAAGVENILALAGDPVLDDDGRPID
GEFEYSLELVELIAEREQFSIGVAAHPEGHPRSVDLATDRRHLATKLEIADFAITQFFFE
AEPYLRMVDELAALGCTKPVLPGIMPVTNVGQVTRFAQLAGAAFPAHLADRFESLADDPA
GVRALGVELATELCQRLLDEGVPGLHFYTLNRSTATRDIARELDLTQ
>A0A6J6L7L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSQLREKLENTQDLVFTAEFPSIDGGGMASVEKNVARLAPWFDAVNATDNPAAHAHASNT
TTAIAMKMHGLEPIMQIVCRDKNRIAIQADMMGASLHGITNLSLLTGDDVTAGDEPEARR
VFDIDSAQAINIARAMATGTYLSGRAIKPAPDFYIGAVENSAAPPFDYRIQRALKKHRAG
ARFLQLQICYHPDRLEAFCKGVAEVAPDLKLIPTIVIVKGAKPLGFMHDKVPGIDVPSQT
LARVQNASDQSEEVYALTLELAQHALSLPGVRGLHITDFRHDDSLARFMSDLGRTPRN
>A0A3E4GS94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus comes|TrEMBL
MRIIDKIKADGVHISFEVFPPKTDAGFESVLKATDGIAELTPSFISVTYGAGGGTSKNTV
KIASHIKNDLKIPALAHLTCVSSTKEEVHKVIGQLQKEGIENILALRGDIPQDGQFPLPG
QYSHACELIEDIKKMGDFCIGAACYPEGHVEMEHKKDDIRYLKEKVDCGVDFITTQMFFN
NDIFYNFLYRIREQGIMIPVLPGIMPITTKKQLARSCALSGTAVPQRFRAIVDYFGDDPA
AMKQAGIVYATDQIIDLIANGVRNIHVYSMNKPEVAAAIMQNLSEIVK
>A0A192H1D7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loigolactobacillus backii|TrEMBL
MSLTDLFQKKTVFSFEVFPPKATTPAEKLQATLHNLQAIHPDFISVTLGAGGTGRYGATV
DIADMIQNQLGITAVSHIPGLYLSEDDVLNLLQKLAERNVHNVLALRGDRVPGREPLGVF
KHADQLTTFIKQNSDFDVMGACYPYTHKDATSGVADIQHLANKVAAGADHLISQIFFDNN
QFYNFREKAELAGINVPIEAGIMPVTNKRQIENITSVAGVPLPEKFTCMMERYADNKEAL
RDAGIAYAIDQIVDLVAQGVDGVHLYTMNNSYVAQRIWDATASLFQASATTTK
>A0A3Z7WH98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0T5YZQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|endosymbiont of Ridgeia piscesae|TrEMBL
MTSQTKTAPSISFELFPPKTEQGFENLKRTISQLNQAKPEYFSVTYGAGGSTQERTFASV
DWLREQGIETAPHLSCIGASVEETVAILQHYRDQGVNRIVALRGDLPSGAGLGALGELNY
ANELVSLIRERFGDQFRIEVAAYPEFHPQAPNPETDLANFKRKVDAGADSAITQYFYNPD
AYFRFVDECSRLGIEIPIIPGIMPITNYSSLVRFSDACGTEIPRWIRKRLEGFSDDLESI
RAFGLEVVTELCRRLLEGGAPGLHFYTMNQSEPTLRLCDRLGL
>W9KK14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum Fo47|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A3S3F043|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARYEVDAVIQEFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A5H8R972|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella virchow|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILIREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3S3CZW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHEVDAVIQEFTDMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVA
GSAAA
>A0A2S7ZQY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella tobetsuensis|TrEMBL
MTLREKHQNGQFTITVELDPPKSSSAQKVFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKDIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDHGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNGA
HFVQTQPIYDLEQAKRYIDTMSEFNVPIMLGLIPLKSFKMATYLHEKVPGISLTQDILDR
VEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A1D7W276|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MEASTATNVLDDFSLEMTGKDVPGLQQAAHAIPQGTRVNITFLGNENLEMRLEAAKEVLE
LGFVPVPHISARRLKSETELREFLDALQQAGASDRVFVVGGDPATPEGPYPDSLSVIRTG
ILQEYGVAEVGIAGYPEGHPDISTQTLWEHMSAKSASLTEQGLGQVVLTQFAFDAEAVVA
WVHEVRGHGVEADIRIGTPGPAGIKRLLGYARRFGVGTSAGIAKKYGFSLTNLLGTAGPD
RFLTDLSSYESITSATSGVKTHFYTFGGLAATAEWVQDFTTQA
>A0A3S3JT01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQIRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDQIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A441DIG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETVLTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPIHNFTQVGNFSARCGTLVPAWLAERFD
GLQADPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A2A3Z347|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MSQEVLASLLKSARYEILPTAGVVDRVHEYVVPGRVITVTASTGLTLEATLSTAEQLQAL
GFTAVPHIAARMVQGRTELEEIVDRLTQAGIDRIFVPAGDATPPAGGYAGALDLIIDLAS
MAAPIQHLGVGAYPETHPLIPDDVTVQAMWDKRDYATHLVSNLCFDPGTIATWLARVRAR
GIDLPLILGIAGKVELAKLARVATKIGVGESTRFLRKNTVTFTKMAKPGGYNPRKFLDKL
APVLDNPSMGVAGLHIYTFNQIKDTEIWRRRQLAALGHNDEVPSTS
>A0A0F3H635|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFAHQPNFEVN
>I1XLP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga nitratireducenticrescens|TrEMBL
MSKQPVISCEFFPPKTEKGAQNLLLVQERLAVLKPEFYSVTFGAGGSTQDNTLEAVIAIQ
QRSAETGIGAAPHLSCVGSSKERIRTILQTYIDNGISRVVALRGDLPSGMRDPGDFRYAN
ELVDFIRKETGDHFTIEVAAYPEVHPQAQDAGVDLENFKRKVDAGADSAITQYFFNIDSY
LYFVERCQKKGIDIPIIPGIMPINNYSQLARFSSACGAEIPRWLKKRLEEFYDDTTSMQA
FTTDYLTEFTEKLISLDVPGLHFYSMNKTQPVLTVCERLGLVR
>A0A7X7C8A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MNDFMKRLREEGILADGALGTEIYKRGIFINRCFDELNISNPSLIKEIHDSYISAGALLI
ETNTFTGSRPALAAHGLDGKVAEINRAGVKIARESAGERAFVAGSIGPISWTRKNSGGMT
DSEMKSFFTEQIEALSDAGSDVILLETFIHLDELHIAYEAAREVSNKPVITQVSLKHLGE
GEFEGLLPEYAAAQMENWGADVIGVNCCDGPQGVFEAIKRMSIATKTPLSAMPNAGLPQM
VNGRLMYLASPEYFAEYARRYAMLGVALIGGCCGTTPEHIKEAKKYLKTMRPGQRSNTKS
IVESISKPVSPIPPEQKSLFGAVIGKKFAISVEVDPPLGTDPSSSIDAAKSLKQLGVDAI
NIADGPRAMARMSPIALASLIKGKVGIETIVHYCCRDRNILGMQMDLIGASALGLHNVLV
ITGDPPKMGHYPEASAVFDVDSIGLIRFISNLNLGLDFAGRPIKQATKFLIGCGVNPGAI
DIDTEVERFRSKIASGAEFAFSQPVYDQKMLARFLEKIKDLSHIPFFVGVLPLVSLRNAE
FLHNEVPGMQIPKHILDKMVSAKSGDAQKKYGLEIARDIVSAAKGSGKISGAYIFPPLGR
YETVEKILKGII
>A0A7T7TZG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CS-2|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENFDKDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A7Z6MAD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus sp. MED-G73|TrEMBL
MKSKLQKRLESGLSAITAEIMPPRGGNTASAISKAIKLKDLVHGFNVTDGSRAIMRMSSL
ALCKLLLEANLEPVLQLSCRDRNRIALQAELLGAHALGITNILCLTGDPVRVGDQSQAKS
VQDFNSIELIRQVTSLNKGIDPVSDLLPDGPTNLFAGAAADPNCRGFDGLRRRIELKKTA
GANFLQTQMVMDPKVLERFCKEITEPMKIPVLAGVFLLKSAKNAQFINRVVPGACIPESI
ISRLESSSNPIDEGISIAADQVKSFLGIAQGVHLMAVKAEQQIPIILDRANIN
>A0A7Z9LR81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MHIAEIYKQNDFVLSYELFPPKTDDGLTKLNEHLTRLLAYKPHFITCTYGAGGSTRDRTL
TTIEDVLTLTDIPVASHLTCVQASADEIRAYVQRIVDKGVTNIVAIRGDVPEGQESFQVT
EGGFAYANELVDFLNSEFPDLGVAVGGYPEVHPEAPSAQADIENLKRKVDAGADVIITQL
FYNNADFYRFRDLCVEAEIAIPIVPGIMPVTSFGQLKRVTSLGASVIPEDFASRLKQHED
DKEAQFNIGIEFAIQQTSNLNDHGVPGLHFYVLNKSKATMAVLHEIHPLH
>V8N4R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiophagus hannah|TrEMBL
MTELRGGYFDKNQAETHRLSLFYLEGYPGGHPEADSYIDDLKHLKEKVSAGADFQATQEN
LMGITGDNQPH
>A0A1E5PCK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces agglomeratus|TrEMBL
MALGTASTRTDHALTVRDLLATGKTSYSFEFFAPRTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVGATEQIASDSTLTPVAHLTAVDHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIAHFVD
KCRAGADYAITQMFFEPESYLRLRDRVAAAGCETPIIPEVMPVTGVKQLARLPQLSNAHF
PPAVKERILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHEQS
>M6XQV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira kirschneri str. 200801925|TrEMBL
MKKVSEIYGSTKGPVYSFEFFPPKTPEGDLKLMETVKELSLLNPDFITVTYGAGGSTRDK
TAQILSRISKNYSFPTVSHFTCVGSDKGQILETLKGIRSSGIVNLMALRGDPPKGEGEFK
KVENGFENATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVRNLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A161RAM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. T32|TrEMBL
MTLLPLLDTCPKRMEYGPCGGVGFDGSCEIDAEHTCAFLPRGTVPWTGVDRVSAPDPGPR
TAAATETLASLGTRPWVVADLPARPLSVASIDSCAAVLAGEVDAVLAGDAGTARVQFPPA
YRAHLLQRAGLRVWTGLNMRDRNRVAIEGELAALAVEGVAGVHCVTGDHTRTGHRPDAAP
VFDLDSTEAAALARAAGHVVSVAASPAAPPVERRAARLREKLRAGADVCFVNHAGGAEPV
RRFIDEVAAPVRFIPCVPVVVDHASADVLESFTTLVLPDGFLSRVRSARDPRAEGIALAV
ALAEELLALPGVVGVNLSGGRDGGEESFAEAQAEIARRLR
>A0A358DT76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MRVIEHLDRAKEPLISFEIIPPRRGGDLKSLLGLIDDLVAHRPPFIDITSHPAVLSYEEG
PDGIRKVIKRKRPGTLGVCALIQHKYNVDAVPHVLCRGFTREETEDFLIELHYLGIDNVL
IIRGDDNGYNKPVKEGRTANRFAVDLVSQVGDMNQGQFLEPYLQALPTNFCVGVAGYPEK
HMEAANLDMDVRRLREKVEAGADYIVTQMFFENAHYFRFVEKCRDHGITVPIIPGLKVMT
VKKHLTSLPRIFNCEIPTALADEVETADKDKILEIGAEWTANQAQELLDSGVPSVHFYVM
QSSKAINKVLKRLKR
>A0A2Z4Y7Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sumerlaea chitinivorans|TrEMBL
MRLPEIYAHRRPAISVEFFPPKTPAGEALLAQRLERFRALDPAFCSITYGAGGSTREKTL
EWARRLRNEYGFETMCHLTCVGHSREELRSLLEGLWADAIENIIALRGDPPRGQENWQPH
PEGLRHAVELVRLARSVAPFGIAVAGFPEGHPESPTEQEDLRYLKEKVDAGADVVITQLF
FDNTDFFHYVNAARAVGVSVPIVPGIMPFRTVAQLEKFTTVYARTRNGPARIPEKLRKRL
QGIASDEDAARLGIAYAIEQCEELLDRGVPGIHFYCLNESDAVDAILQSLRSSHRLA
>A0A084H1G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metabacillus indicus|TrEMBL
MALLTDLQTKILIGDGAMGTLLYSHGVDRCFEELNLSKPDDILNVHKAYLDAGADVIQTN
TYGANYIKLSRYGLEDEVRAINRKAVQIAKQAAEGTSAYVLGTIGGVRAFKKGAYSLEDL
RRNFREQLYLLLNEEPDGLLLETYYDLEEMKTVLEIARKETDLPIITNISLHEIGVLQDG
TPLSDGLSQLEELGANVVGLNCRLGPYHMLSSLEEVPLPEKAFLSVYPNSSLPTIEEGRL
VYGSGEKYFAESALAFRNQGARLIGGCCGTTPDHIRAMASALKGLPPVTEKKVKARKEEI
SIASAAERKYPPLQDIVKEKRSIIVELDPPKKLGIDKFLKGAKALQEAGIDALTLADNSL
ASPRISNAAMGSIVQQTHGIRSLIHITCRDRNLIGLQSHLMGLHTLGLTDVLAITGDPSK
IGDFPGATSVYDLSSFDLISLIKQFNDGLSYSGKPLGEKTNFSVAAAFNPNVKYLDKAVK
RLEKKIACGADYFISQPIYSEKQLIDVYEETKHLTVPVYIGIMPLTSSRNAEFIHNEIPG
ITLSDSIREKMANAGDDKEKSYQEGLAIAKNLIDAAFDLFYGIYLITPFLNYELTVELTN
YIHKKESEATERKITHV
>W7DP52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria fleischmannii FSL S10-1203|TrEMBL
MLQIVRENTDLPVIANVSMHEPGLLQNGEKLPDVLQEIADLGADVVGVNCRLGPYHMARA
LETVPLLDNAYLAAYPNASLPEMQEGKIIYQAETDYFQEYGEIFRKQGARIIGGCCGTTP
EHIRAFRAGLTSTKPIKTKEVRPIIELVPEEPSPLEGVRLLDKVREECTVLVELDPPRTF
DTEQFFEGAKALHAAGADAITISDNSLATPRISNMAIASILKHEYDIKPLIHLTTRDHNL
VGMHSHIMGFHKLGLHDVLAVTGDPTKVGDFPGASSVFDLRSVELIQLIKKFNDGISYTG
KSLKEKARFHVAAAFNPNVLNVEKAVRLIERKVEYGADYIITQPIYDTQKARVLKEALKE
AQISVPVFVGVMPLLSSRNAEFLHNEVPGIRLTNEVRERMREAEKAGRGNEEGMLISKEI
IDSISEHFNGVYIITPFLRYDLSLELLQYAKSKEQVHVI
>A0A2N6BSV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MEDHNSRLRSSLKDPAEFTLTFELVPGRGGRTQEISRIVNLAKDIAADGRFQALSITENA
GGHPALSPETLGTEILAMGSEVVIHLSCKDKNRNQMESLLFGWDRNNLHNLLVIAGDYPK
EGYCGFPKPVFDLDTIHVLDLLSTMNRNGPIYKDYDARGELKKNIPFLKGVVVSPFKLLE
SELLLQYYKLHRKIAAGADFVITQMGYDARKFHELLQYMQHNQLKIPVMGNVFIPSLKVV
ELMYEGKLPGCLIPDVLYEQIQWEARTADKGKKARLVRAAKLLAVLKGLGYAGAHIGGPA
LTFEDLNFVLTQADELASDWQSLIPDLSFFPPKTFHFYGRDNATNLNSEKAMLRPPATPS
WISAYSFSHWVHEAAFEPEGRFYDFCKKICLQLGDTRLRGPLATFELISKVALFGCQNCG
DCTLEKLGFLCPQSRCAKYLLNGPCGGSHNGWCEVYPGKKRCLYVLAYERLKPYGLEKKF
KSGFIPPRDWSLNNTSSWVNFYRGLDNFAKSEAPSDTCTKK
>M5T3P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula sp. SWK7|TrEMBL
MTLADQYSSDGCAISFELFPPKTAEGINSLCENVERLMQFNPKYFTCTYGAGGSSQRTTL
DVLERVKKLTKLPVASHLTCVGSNTDQLCEYLQRATDIGVDYIVALRGDPPKGSTEFSVT
DGGLRYANELVDLIRAKFGDLGIAVAGYPEVHQEAVDAKTDLENLKRKVDAGADIVITQL
FYDNADFYRFRDDCVAAGINVPIIPGVLPVTNFKQAQRIAGMCKAAIPASLESEMTRDDA
PEHQFRVGVEHARKQTIDLLENGVPGIHYYVLNKSDAAVELLDGLQLAGQP
>A0A7V5V5K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKPDFLEYIQDHVVLGDGALGSYLFERGVERGRNLDLLNLQAEETIFSAHEEYIRAGSQL
IETNTFGAGRFKLREAGAEDQVREINRAGARIAAKAAGHQVYVAGSIGPSGETFPLEEGE
VTEEEIRTSFTEQVLGLAEGGADVLIIETFSQLQEIVLAIEIARREAPELPVIAQMVFPA
RGMTVHGEDAFNCGLRMRKAGAVVVGTNCGRGIDAMVTAISQMSPLAGEGTPLSAFPNAG
MPEMVGGRTIYPAQPGYMAARAREMIKSGVHLIGGCCGTTPAHIQEFRSALRIKPVRVRG
ERIAAVDRESDGVEKAFKPGGFLASLENKRLPIIVELDPPTHLDVESVLHGAEELTRAGV
DAVSLGESPLAILRTGNLGMAARIRQRCGVQTIIHQTGRDLNGLGLQSRMMEAHLLGIEA
VLAVSGDSAAGTDQPGVTGVFDLRSEGLIRMLAGLNRGVNLAGRSIKKETNFSIGAAFSF
RPAKPGLQISRLEKKTALGARFAMTQPLFSKEVVEQMMEAVNHLDILIFPGIFPLISSRN
AEFLHNEVPGISVPADLRSRLASYDQVADQRKAALEYTGRLIEDIQPCIRGLYLISPLNK
WDIVLDFVQQVRGSE
>A0A7T0C406|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrohelix vancouverensis|TrEMBL
MKIIDILKQTHPAFSFEFFPPKNDAGFETLYKTIEKLKPLNPAYVSVTYGAGGSSRAQTV
ELVSRIKSEVGIESMAHLTCVGHSAEEIRDVLELLESKGVENVLALRGDPPQGQTEFVKP
TNGFEYANELVGFIKKDFSFCIGVAGYPEVHPECADAETDTEHLKNKITQGGEFIVTQLF
FDNSYYFDYVKRLRSAGVTVPIIPGIMPILNLKQIIRITEMCKTRIPDSLQAKLEKVQDD
DEAVRQIGVEFATEQCADLLQGGAPGIHFYTLNRSNATLAIMEALMKQSQGGP
>A0A0W7U4C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas schubertii|TrEMBL
MGFHSARQVEALNQSIADLSGDISVSFEFFPPGSESMEQTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGVEKPDMYAADLVALLKAEANFDISVAAYPEVHPEARSAQSDLLNLKRKIDAGADRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLTKFAGFTNVKIPRWMHQRFE
GLDNDQATRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKSV
>A0A1Y4ETJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeromassilibacillus sp. An250|TrEMBL
MKIKDLLQNKKVTFSCEIFPPKAGADMSRMDEIIRDIAALHPDFISVTYGAGGSTSKRTV
EIASKIQDTYGIPAMAHLTCVSSTKEEVVTMLDRIEENHIENILALRGDIPQDMDFPSPQ
HYRYACELIQDIRSQKGDRFCIGGACYPEGHVECEHKEDDIDYLKQKVESGCDFLTTQMF
FDNNVFYNFLYRIMAKGIQVPVVAGVMPVTNSRQIKRSCELSGTTLPPRFKAIADTFSDK
PLAMKQAGIAYATEQIIDLLSNGVNHIHLYTMNNPEIAAKIMDNLSGILRDEEA
>A0A358C574|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus sp|TrEMBL
MTERTYSFEFFPPKTAEGADKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETVREIQT
DGSEAAPHLSCIGSTEESIRDILNEYKSQGIRHLVALRGDLPSGSMDAGAFNYANELVAF
IRRETGDWFEIEVAAYPEVHPQARTYTEDLANFKRKVDAGANAAITQYFFNADAYFNFVE
DARAAGVSIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLPSLRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPTTTIWQRLGLS
>A0A2N6V5E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces graevenitzii|TrEMBL
MPFSNDIYACPCTHDHEPTLLSFEVMPPRKPSLEAPFWQTVDQLLQVRPDFMSVTYGAGG
KDRSNARATVHRLVADTPIQPIAHLTCVGNSTAEVVSTVYDYLDSGVRTFLALRGDPPAG
ETSWEPGPNGVASATELIHLIRTVEQRRCDAHPGEALRSAFKPLTIAVAAFPAGNPAAGT
TPTQEVERLLVKQAAGASFAITQLFWNAEVYASFVERARRAGVHIPIVPGILPATDPARL
RRVQDLTGIEVPEHLLSTLAGYQHQEQRDAFGAAFGSKLIHSVLEAGAPGVHLYTFNKAK
PVLDILSLMGVEPSAHHSPLLAR
>A0A1Z8M5H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula sp. TMED11|TrEMBL
MTLATLFNNSERCEISFELFPPKTDKGMQNLQDNVQKLLRFNPAFLTCTYGAGGSTQSST
LEVVELVKQISGLPVASHLTCVGSTVEQLNDYLTEAKRRGADYIVALRGDPPQGSDEFLA
VDGGLSYANELVELILRDHADQFGIAVAGYPEVHQEAPNAQTDLDNLKRKVDAGADIIIT
QLFYDNADFYRFRESCEAAGIRVPIIPGLLPVTNYKQAKRIAGMCKAAIPTEMSTAMSAN
DDPDFQFECGVQHARNQTIDLIHNGAPGIHYYVLNKSDAAEQLLSDIDFEKKA
>A0A031GNE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium lividum|TrEMBL
MHRDNPRPAGNITHAYSLEVSTKDIAALSAAAPRILTGSTIAIPYLPRENDDARLAAARA
VRRLGFEPMPHLSARRIASLAGFELFVQRAAAEAGVERCFVIAGDPSIPVGPFADSAALI
DTGIFERAGMKVIGVGGHPEGHPVMSKAEQWEVLERKCHSIEMRGMAPLIVTQFAFDADI
VLTWLEALRAHGINHPVRVGVPGPASIAVLARYAAVCGVGACASMWSKYGVSIGKLFGTA
GPDLFVDRLAAGLTAAHGEVSLHFFPFGGIVQSVKWIEQYRARTDPGL
>A0A3D1AIL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MLVKDILEKNRISFSFEFFPPKDESGWEYLFATISDLMPLKPAYVSVTYGAGGSTRDRTH
KLLVRIQQETSLTVVSHLTCVGSNREETGAILRNYAASGVKNILALRGDPPKGQTDFVQP
PDGFAYAADLVAFIKNNFPQMGVGVAGFPEGHPATPNRLLEMDYLKAKVDAGADYIVTQL
FFDNRDFYDFRDRCALAGITVPIIAGLMPITTKSGMVRMAELAAGARIPASLLRGLDRAR
SDEQVEKVGVHWTTEQVRDLIDNEVRGIHFYTLNHSRQALDIYQTLGVEDSIQLGA
>S0N517|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus saccharolyticus subsp. saccharolyticus ATCC 43076|TrEMBL
MTRTNFSLEIVPPNERFSYEEVQQISEQLSKLHPLFIGIPSINKSKMTEMIRLAGDIRKL
QTNALPHLPARFMTKKQVQDVLKILQEQEVFQLLAVSGEVMPHDHPTGEFAFANELSHYI
NEQTNRFTILGTCHPEHIATNELAQLEMTYLQQKVQDGCQQFLTQLFFENDGFYRLHDKY
IKQLTTPLLVGVLPILSYQQVLNMATRNQLAIPRKLAILLDKYQYDPISMRAAGLDYTLY
QLDELIHYGVDGVHLFTMNDVPAAVEIYRNFW
>A0A6S6ZJJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter deleyi|TrEMBL
MSDSTTPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQASSPSADLDHFVAKVNAGADAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQNLLDNGAPGLHFYTLNHADAPLAVWKELAV
>A0A5K7TQJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. KU43P|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMAVAKQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKDELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITHMCEQLLQGGAPGLHFYTLNQADASLAIWNNLKLPR
>A0A2X2WLS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter koseri|TrEMBL
MVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2A4IMQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira sp. G79|TrEMBL
MNNNVENFIKKLENKDEYTFTLEISPQAKYDLGYIEEKINNANISDYIDAFVVTDSPFAN
LKISSILAALQLKQRLNNNKPFITTQTMRDKNSIALQNDLIGANYFDLRMILAVTGDAIA
NGNQKQAKAVFEGNSNLLINIIKNLNNGKSLGEFSFKEPLKHIYPFCVINSYAKNNDNLK
VRLAKKANSGVKAIFTQPIYEIERLELLLKWIDELPLKEKPVLVPGFFPVLTYKTAYFIY
YKLPGAYIPEDWLNKLKDASDKSPEEEKKVAYELSANLFNSMIKKHKKMHIMSMNNYDFV
VSLLKNI
>A0A1S8CWH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkanindiges hydrocarboniclasticus|TrEMBL
MATSISFEFFPPKTDVGAEKLVVVHQELQQLNPQYFSVTYGAGGSTRERTLSTIDALHGQ
GAPVAPHLSCIGDDKARIAELLDIYKAKGINRLVALRGDLPSGQVGLGELPYATDLVRFI
RDHSGDYFHIEVAAYPEMHPQASSFDQDIERFAGKVRAGANAAITQFFFNADSYFYFIDR
IRQLGIDTPIIPGIMPITNASNLIRFADSTGAEIPRWIRKQLATYGDDSASIRAFGHDVV
VKLCQRLIEGGAPALHFYTMNQTEPNRQLVKDLGLA
>A0A5M7BA81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algibacter amylolyticus|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPKKGKNIQDLYNNIDPLMEFKPPFIDVTTSREEYVYID
KGNGLLDKRITRMRPGTVGICASIMHKYKVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKDEPYFKPVKGGNAYASELVEQIATLNRGQYLHDDVVVEHNSDFCIGVAGY
PEKHMEAPSLVTDLRRLKAKVDAGADYVVTQMFFDNNKYFEFVDKAREMGINVPIIPGIK
PIAVKRHLQILPQVFKIDLPQDLIDAVEGCKDNQAVRQVGVEFAIQQSKELREAGVPVLH
YYSMGKSDNVKAIAQALF
>A0A7C1Y7B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSFREALESGRFVVTAEVGPPKGADVEEMVHHIELLKGKVDALNFTDNQSAVMRMNSLAG
CAIAVQHGVEPILQMTCRDRNRIGLQSDLLGAHALGVKNVLCMTGDHVSAGDHKGAKPVY
DVESVQLLGIVESLNNGRDMSGNELKGATDFFPGGVVTPEADPIEPQLMKFEKKIRAGAR
FFQTQAVYDIEKFKEFMKHARKFPVKVLAGLVVLKSAGMANFLNNFVPGIKVPQELIDEL
KAAGKGKGLDAGMSICARHIRQLKEEGICDGVHIMAIGMEDKVPEIMERAGL
>A0A7L8TZD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. CW117|TrEMBL
MTALSFEFYPPKTDDQRAQLDRTASKLKVHAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLQAAPHLSCVGGTREEIRELLKLYRAIGVRRIVALRGDLPSGMGFPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLRHFKAKIDAGADAAITQYFYNADAYFQFVDA
TRKLGVDVPIVPGVMPISNFSQLRRFSEQCGAEIPRWIAKRMQAYGDDVDSVRAFGADVV
AALCERLIAGGAPSLHFYTLNLARPTSAVLQRLGHG
>A0A4R1C158|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides jejuensis|TrEMBL
MDLAARIRDRQGGFVLFALTPPRQSTAPERVAEIAAATSARLRPLGLDGLVLYDIDDESA
RNPSERPFPFTPTLDPATYLADELSDWPTPVVVYRAVGKYEPTALEAWAATQDAARALTV
LVGAASSGAAAPLSLSAAQDLARSSNPDLLVGGVAIPERHTRRGNEHERLLAKQAAGCRF
FVTQVVYDVNAAKSLVSDYAYACQAAGIDPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLRHAEDTLQASYDQALATATDLIAYCERLGVPFGLNVESVSIRKVEIDASVELARRL
IEELAAPA
>A0A7V1CMF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSFRETLESAKFTVTAEVGPPKGTAIADMIHHMELLKGKIDAVNVTDNQSAVMRICSLSV
CKIAMEQGLEPILQMTCRDRNRIGLQSDLLGASVLGIKNVLCMTGDHVSAGDHKDARPVY
DLESVQLLKTVDSLNNGRDLGGNEMKGATAFFQGAVVTPEANPLEPQLMKFEKKIRSGAR
FFQTQAIYDIEKFRGFMEFARKFPVKILAGLVVLKSAGMANFLNNYVPGIKVPREFIDEL
KEAGKENALDTGLSITARHIKQLKDEGVCDGVHIMAIGMEDKVPVILERAGLL
>A0A2C6WK20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus edaphicus|TrEMBL
MSQLLDKLQHNILVADGAIGTILYSEGLDTCPEAYNITNPDKVERIHRTYIEAGADIIQT
NTYGANFEKLKPFGLEHKVKDIHYAAVEIAKQAANDETFILGTVGGFRGIKQEDLELSSI
QYHTEIQIETLIDAGVDAILFETYYDLEELTTIIKATKRKYDIPVIAQLTALNTNYLRNG
IEINTALQQVVESGADIVGLNCHHGPHHMQQSFSHIELPDGAYLSCYPNASLLDIENSKF
KYSDNAAYFGKVAEQLINEGVRLIGGCCGTTPEHIQYIKSSVSNLKPVTEKNVIPITKYV
NHPEKPTQKQNLTSKVKHRPTIIVELDTPKHLDTDLFFRNIKKLDDANIDAVTLADNSLA
TVRISNVAAASIIKQHYDIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKTQTNFNIAGAFDPNVRKLDGAVRR
LEKKLESGMHYFITQPVYSKEKIKEVYEATKHLDVPLFIGVMPVTSYNNALFLHNEVPGI
KLSEDILDQFVAVKDDKAKTKALSLKLSKELIDTVHEYFNGLYLITPFQKVDYTLELANY
SKSITSTKQEAIL
>A0A2Z6RCD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus clarus|TrEMBL
MKITDKINNLETSQPFYSFEYFPPKTDEGLNNLYDRLKRMSHLDPLFASFTWGAGGSTID
RTTEMCATAQSLYGLESCMHLTCTNVVRGTIEKALNEAKSTGIQNILALRGDPPRGQEYW
TSCDSDFTHAIDLVRFIRKEYGDYFCIGVAGYPEGNPDSDNKEQDLKFLKEKVDAGADFV
ITQLFYDVNMFVEWRDECRKIGINVPIIPGIMPIQGYNSFRRITNLCKIHIPLDILNVLE
PIKHDDQAVKDYGVTLAVSMISKLCNENNTRGFHLCTMNLEKSVRLILEKLRFVQTEEER
NLRRLNRRRSSAGFGPNDIIRQEPDGSLPTAKPVIWKEKNIDYLGRPEDWDNFPNGRWGD
ARSPAFGELDGYGVSLRIPPEQALEYWQRPTTLDDLKQVFKSYILGEIPALPWYEEPLYA
ETEAIRSKLVHLNELGFLTVSSQPAVNGARSDDPIYGWGPRGGYVYQKAFVEFFASPENF
EKLAEKITGNPWVTYYASNRNGDFRSNTKEDAPSAVTWGAFPGKEIVQPTIIEKVSFSAW
KDEAYALWTEWEHLYPKDSPSQRLLKDIGDNWWLINLVYHNYVNSEEIWEIFFKS
>A0A7C0UM99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
LCLTGDHVNAGDHKQAKSVYDVESVQLLKIVNGMNNGFDMSGNELQGATDFYPGAVVTPE
SVPLEPQLVKFEKKVEAGAKFFQTQAIYNMDKFKDFMKYARQFPVKILAGIVVLKSAGMA
NFMNKNVPGIMVPQDLIDEMKAAGKEKALDTGLNIAARHIRQLKEEKICDGVHIMAIGME
DKVPEIMERAGLL
>A0A2N1YV98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium HGW-Gammaproteobacteria-13|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPAAPHLSCVGDSKAELRELLTLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGANSAITQYFFNADCYFY
FIERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTDSIQAYG
EQVITEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A2B8B8I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum palustre|TrEMBL
MTAPTSALPSISFEFFPPKSEKMEQSLWQSIRRLAPLSPSFVSVTYGAGGSTRERTHATV
CRIQDETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGRYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDAYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCNASMPAKLAETFEGLDD
DPETRQLVAATVAAEQCQALQAQGVNDFHFYTLNRSDLTIAICRMLGVKAKAAPAAAAVA
G
>A0A521M162|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reyranella sp|TrEMBL
MSPDTGPLSTSAGTSEFPARAPQRLKVSFEFSPPKTEAAERTLWETVTRLTPLQPTFFSV
TYGAGGSTRQRTHETVARLKSETGIDAAAHLTCVAATQGEIDDVARAYWDAGIRHIVALR
GDPPGGMGGKYSVHPGGYENAAALVAGLKKIGNFQISVAGYPEKHPDSPDATADLENLKR
KVDAGADRCITQFFFDADDFLRFRDRAAAAGIHVPIVPGIMPVSNFQGIARMAGLCGSKV
PAWLAELFDGLEDDVETRRMVAATVAGDLCRRLRGDGVDQFHFYTLNRADLTFAICHLLG
VRPPRNGAPK
>A0A1Y6K603|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevefilum fermentans|TrEMBL
MANPKYGNIFTIMPILTPSRRWQPPFYPFKKRSFSERLEEALERSFKGLIWGCRMCGNCL
LQETAFICPMACPKGYRNGPCGGSTPESCCVDESRPCIWHAIYVRAEKMNRLEKLLEVFP
PLDWDKAGTSALRDVYNKINSHGKLRTISTIFRSSTTERKSKWERFFKDIRQPAWWDGDA
YPHPPKPHEPVSSLEKLLSEGKFVLTCEIVPPAEDNFPVLDAKLAELSGLVDAVNITDNA
SAIPRLSAFACAQQALTSGIEPVLQMTTRDRNRLSLQASLIGASAAGIRNLLLVTGDHPI
KAIAPFSHMDAWDLDSIQAVWIARKLRDEGVFLDGRTMDHPPSYFLGSAAAPFASEPRFQ
ALRAEKKINAGTQFIQTNLIFDLPRFEAYLEELEKRNLLSRVHLIAGVAPIKSLAAAKYL
RQLPGVVIPDDIMQRLADAKNTSTEALKICLELIEKLRALPGIRGLHFMAVPNTDHLKKV
LIESGLRE
>A0A096A828|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella histicola JCM 15637 = DNF00424|TrEMBL
MDIKTLLNDGTTERRFSFEVLPPLKGNGTASLFRNIDQLKEFNPQFINITTHHSEFVYHE
REDGLLERQSIRRRPGTIAIAAAIQQRYGIPVIPHVICSGATKEDIEYELLDLQFLGIDT
LMLLRGDKAREDRQFTPTKGGHRHTTDLIEQVKLFNDGKFIDGSEMKHPGNPFTYGVACY
PEKHEEAPNIEQDLQYLKKKQELGASFAVTQLFYDNQKFYDFLQRARNMGITIPIVPGIK
PFAKLSQLNIVPKTFHCDIPEELAGLARLCKNDDEARELGIEWATRQVKDLYAHGINNVH
FYTVSAVNSVHEVVRRLL
>A0A1Y6F576|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altererythrobacter xiamenensis|TrEMBL
MSPTVDQMREAQLALENPLFSDVAGDIDISFEFFPPKTEKMSETLWHSVETLAPLAPRFV
SVTYGAGGSTRERTHQQVLRIQNEAGIPAAAHLTCVNATREEVDAVARHYWEEGIRHIVA
LRGDPPEGDAKYRPHPEGYQNAVDLIGGLKKIADFEISVAAYPEVHPDSPDAQADIDNLK
AKFDAGATRAITQFFFDPQCFFRFRDKAAAAGIDGEIVPGVMPVVSFAAVERMSGLCGTS
IPPWMKGLFEGLDEMPDARQLVSATIAAELCRKLYAGGVRQYHFYTLNRAELSYAICHML
GKRPGENQS
>A0A1I6SYT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas viscosa|TrEMBL
MTGPALSLSEARALLLSPLGPVARAGHDASRPRVSFEFFPPKSDEAEANLWQAVTRLAPL
RPEFVSVTYGAGGSTRERTHRTVQRILSETNLAPAAHLTCVEASRGEVDAVIDAYREAGV
RHIVALRGDPPGAAGIGGAYVPRADGYANATELTAAIARRGDFEISVGCYPEGHPESPSP
DHDIDVLKAKVDAGATRAISQFFFDIDAFLRFRDRVRAAGIAVPLIPGIMPVTNFVGLRR
MSAACGAAVPAWLATHFDGLDNDPETRRLIAASVAAETCARLQEEGFADFHFYTLNRADL
VYAICRVLGVREERTDA
>T0XT85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospirillum sp. Group IV 'UBA BS'|TrEMBL
MTFRQALAERRFLITAECSPPKGTETGDLLRKLLPLKGRIHAMNVTDNQTAVMRMCPFAM
GLHLKTIGIDPIVQLTLRDRNRLALQSDIIGMSSLGIRQVLCLSGDPAAIGDHPETKPVF
DLTSPELIRAITLLNGGSDLAGKDLSGATDLLPGAATSPEGDLSTEKKRFEEKFDAGRPL
LPDPGCLRPGQA
>S9RH02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. tigurinus 2426|TrEMBL
MTMSRQTPSLSFEVFPPNPAVGNDRIISALQDMRELTPHFISVTASNNKFNIKETTVRLA
DFIQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVRKILALRGDIIPDVEPQKDFRYA
TDLIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERF
YDFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLR
AAGLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A4D7DQN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. EMRT-2|TrEMBL
MTTSYDQLREARTALDTPLFAGLPGDIRVSFEFFPPKTDALMTQLWDVVTTLAPLEPQFV
SVTYGAGGSTRDRTHGTVARIISEARLPAAAHLTCVDASKAEIREVAEGYWQAGVRHIVA
LRGDMGAPGVPFTPHPEGYANAAELVAGLKAIAPFEISVAAYPESHPDSPSVQADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAAACGAA
IPAWMDGLFEGLDTHPASRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPGRPALEKAA
>A0A0Q5HE77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia sp. Leaf325|TrEMBL
MAIELLPTDGATRLPVSFELYPPRTDAAAIALGRTIDRLTEVDPAFISVTFGAGGSTRDR
SLTVLSYILENTSVQPMAHLTCVGSSAVEANRLVRQFLDAGITSFLALRGDPPLDGTPLS
VGDLQSAAELVQLIHRVQQEREPFAQEAVRGTPGGTRLRARPRPERVAVAAFPNGHATSR
GPQQEIDALLAKQASGANLAITQLFYRADDYLAFVERARAGGVSIDILPGIMPASSAPRL
RRIAQLTEEDAPDELLIALEIEPTEEGRSEIATAFFSELAAEVIAEGAPGLHLYTHNKHT
PVLDVLERLDRLPRAAHGSIKENA
>A0A533XHR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MVECLKLRQKLERRDFLRIVEVFPPNFTAERDREPLIGLRQKTRDFLERVKKIQNLADAI
LIADVKDLSRLKLGTIYSAAMVQEEVGIEAVPVITARDSNRPAIRSAILTALSLGLDSLM
FVWGDTYADDGAKNVYDYRGVGEMMREAGALFERAGVRPTFFAPIDLATLDAPRGRHLAH
SRLKSGAEYLLAQPPTADVSHTFPSHMRTLRSRRLNSRVLLNVFPFRSSDDIEYCRKKFG
WDLPPHLDAIAEKGGEPELLKEAKRVADRLRAAGCQGVYVSTRGRPELARFILD
>A0A432FH35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MLLIYRSKVLIMYNQKPPMTVRYEINPPKISGDGQDVRNVLFERIETISSVCNGIHLTDS
VLGIPRVSPFKIAKQIRESNKNIKLTCSLRVRDKNLNDIEKIVQESIGTVDGILVLMGDK
SDTMPNKDNLIPSQVVKALNDNGLDKKIELFLSLPSNPNFAKIQKKIDAKPVGFVTQVIH
SKDQVEKIVNYLRPNGFKIIPCLLLPSKNNLKSAEFLKIDWSNYEENIIEFINEIHSIDS
EILVTSPNDFKRAHETLTKLAT
>A0A8B2WZ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster clostridioformis|TrEMBL
MKIRDILAEGKPTLSFEVFPPKTEDAYDSVEKAAAEIAKLKPSFMSVTYGAGGGTSDYTV
GIASAIKEEYGVTPLAHLTCVSSTREKVHHVLGELKERGIENVLALRGDIPQDGSTPREY
HYASELIWEIKKAGDFCIGAACYPEGHVESANKSVDIDYLKQKVEAGCDFVTTQMFFDNS
ILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTYLPSRFMSIVDRFGDNPAAM
KQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>R7H8L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:38|TrEMBL
MKPISEYLKENYLICDGAFGTYYAEKYNTKELPELANLSAPERVREIHEEYVSAGAKLIR
TNTFAAHSDLLNCGQGLLAENVKSACRLAKEAADGKAYVAGDIGPVPAEAAFDTEAAEKH
YLFLAKLFVESGVDAVVFETFSELETILPVIRYIKEETPLFVIVQFAVSQYGYSSAGLSM
HRLFEEAQKSPADAYGLNCGIGPGHMATLFQNIKFRTDKYITALPNAGYPHNISNRMVFS
ADNGSYFAERVCDIMQVRADIAGGCCGTTPEHIRRLSAKTAGMTKTARRAEQKICENEKP
VQNNAFYRKKERTGKKLIAVELAPPLGSDDKKLMEAAHALRKSDVDVLTFPDSPSGRTRV
DSILMAEKVSKETGMCVMPHLCCRDKNAIAMRSQLLGAHINGIDNFLVVTGDPVPAVARQ
TVKAVFNFNSIGLMNIIHDMNTEQFADSPVVFGGAINQNRRNLNVEIDRIRKKMEMGADF
FFTQPVFTEKGVNLLRQIKEETGARILCGVMPFVSRRNAVFMKNEMTGIEVDEQIIARYP
ENATKEEGEAVGIEIAREVMAQTADFVDGYYFSFPFNRVYLLEKILQL
>A0A181Y5D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella oxytoca|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAKDYWDSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMFE
GLDNDPETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1J5EB75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium CG2_30_51_40|TrEMBL
MKDESRLKQLLDGGHFAVTAECGPPKGADPGAVLRKAGLLKEKVDAVNVTDNQTAIVRMS
SIAACTVLLSAGLEPVLQMVVRDRNRIALQSDVLGASALGIRNILCLSGDHQSFGNQPSA
LGVFDLDSMQFIEAVRGMRDAGTIMGGEQLTSAPAVFIGAAANPFADPLEFRVVRLAKKI
SAGAEFIQTQCIYNMERFKKWISLAEDRGLLEKAYILGGVTPLKSAGMAKYMKNKVAGMD
IPDDVIKRMDAVPKERQRQEGIGICVETILALKEIKGVKGIHIMAIEWEDAVGEIVERAG
LLPRPKVD
>A0A5B8U2I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Baekduia soli|TrEMBL
MRIDQLLGGDEPTFSFEFFPPKTPEGEANFQRALRELAPLEPSFVSVTYGAGGTTREKTV
ETVRQIKDELGLEAMAHFTCVGATTDELRVTLEEIRAAGIDNVLALRGDPPRGQEEWVAS
EGGLEYSHQLVALLREDYDFSIAAACFPEGHIHATSPEDDLRHLKEKVDAGVDYLITQLF
FDNALYRDFVDRARAIGITVPIIPGVMPITGYGQIARITAMCGATMPEHVLAELDARKDD
PEAVADFGVSFATMQCADLLAGGAPGIHFCTLNRSPATRAILSTLRLWRPWDAAHTGLGE
PRRPPAVA
>A0A2U1JMP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium psychrotolerans|TrEMBL
MKVTEHIENAQGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVD
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFIPKEGGNDFATDLVHQINQLNQGKYLHNVMDIDNKANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDSGADYVVTQMFFDNAKYFEFVAKAREIGITVPIIPGIK
PIAVKRHLQILPQIFRIDLPEDLINAIEKCKTSADVRQVGVEWSIQQSLELKNAGVPVLH
YYSMGKSENIRQIAKAIF
>A0A6C1PNZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MHISAILAARRPTFSLEFFPPKTEPGWERLFRVMERFQRLNPDFVSVTYGAAGTTRNQTN
RLVRRIAGETSLSPIPHLTCVCHDRDEIERILDDYLEIGISAVMALRGDPPVGGDRCDGA
YRYAAELVEHIVGYCTRNSPNGESPFGVGVAGFPEGHPATPNRVVELDNLRRKVDAGADY
ICTQLFFDNRDFYDFRERCRIAGITVPIVAGVMPVTSRANFERLPSLALGARYPAAFMRA
VGSCATDDDVRRCGVDWAIAQCSDLIANGVDGIHFYTLNQFGPIRDVWEAACAVTSSR
>W0U2A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus bicirculans|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>D0WSI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio alginolyticus 40B|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSAKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKATTGLVAAPHLTCIDATREELINIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFD
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRAVVGA
>A0A1R1YG16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium culicis|TrEMBL
MANLGDRLSRMKSWNPLFSTVTWGTGSSDCTQSIDFSSKLQNDFNLDAVLHLTCSNMSKE
LIDNSLKTAKSKGIRGILALRGDIPLELTSLSNNSTGNNNCFKYASDLVEYIKSIPEYSE
YFTIGVAGFPEGYTSATISESFDSATNSSSSTSRNFNSSSTSLLDKEMEELKWLSYKVEK
GADFILSQVFYSTDKFVDWYKKCRDYGITVPIIPTILPIQTYGSFKRIINLTKVSVPSSL
NDQIELVKSDDLMVKQIGIDFCCSQISTLTKECNILGFHFSTLNLENSILAILTRSGLLR
NFNDPSDLSSLPANFSASNTNPSLPVGGESATWDEYPNSRWGDARSPAFFNESIYGQSSF
INTDQLLQWGFPKSLDDINSLFSKYISGDIPSLPWTSDNINSSNSDFVISVLNYLPKVGI
WPMASQLAVDGVQSSDPEFGWGPANGYVYQRSFIEFFAVEPVALKILELLKNNTKQDFSY
YASKLNFDTNEPVILSNAIVNNSSFDPSINSHLLEIESTALSWGVFPSSPVIQSALIDKL
NFGYWSKEAIQLWRVWSSQIGSFSKESKRFIDSVADSVYLINIVANDYKTPEKLFSFLKE
EF
>C4GHL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingella oralis ATCC 51147|TrEMBL
MDVWMRPMPRQPENPIRNPTMTTSRSLSFEFFPTRTPEGRAKQILVRQELKQFNPQFFSC
TSGAGGSTREGTLQTVRDILNEQTPAAPHLPCIGMLENEIVELLQQYKDIGVNRLIALRG
DIPSGTGFGMEGLRYANELVALVKQKFGDHFHTIVAAYPEYHPQSQNAADDLRYFVQKVN
AGADSAITQYFFNADAYFNFVDDAQRAGVDIPIIPGIIPVDSFTKLVRFSDMCGAEIPRW
LRLKLYSYADDAESIRAFALDVVTHMCERLLQGGAPGLHFYTLNRADLSAEICKRIYGAP
AK
>A0A829ZW42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermanaeromonas sp. C210|TrEMBL
MGLKTESRLERLLSQGHFVVSGEIGPPKHASPEGILHHAELLKDYVDAANLTDNQTAIVR
MSSMAAAVHVLRAGVEPIMQMTVRDRNRIALQSDLLGAYSLGIRNVLCLTGDHQSFGNHP
TAKNVHDVDSIQLLKIVKDMRDDRKFACGEEIKEHEPRFFIGAAANPFADPFEFRVLRLE
KKIKAGADFIQTQCIFDMERFERFMALVRERGLHKKAYILAGVMPLKSAKAARYMQKSVA
GMVVPDEIVARMEKASDPRTEGVAICVEQIKHLRTIEGVAGVHIMAVMWEDIIPIIVKEA
GLYPRPSAH
>A0A0U4D120|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cepacia JBK9|TrEMBL
MSSLKQALNDGRFVCVLEVVPQQSPSRLAALEPIVQRGHLAGWPLLPAFADRVGLHSDLS
PLEAAEALGNPASSLLHFSGKDRERADLLLQMDSMKALGVAQLLLLSGDRLPGHHDQAQV
RYLESVPALQIAREHGPDWLLGAALNPFKYREEEGGAQYLKAQKKLLAGADFLTLQLGFD
AAKHIEAQTWMRAQASMKPMLACVMGVTDKRAALLQAVPGIVITESMRMLLGREQRVSQA
YASARSVERLALQILGLQLMGYAGAHVSGVHTLDELLSLEQAITEQRDSVTSLTEWSERW
RASWQLPGVPQVSFTPESGAWEMGQSDVTATRRERLRHRLLSSIHDRFFSRTGWLGRAFG
WSVTRSIWKVGMAANALHAIERTIKRPLVGCDTCGRCRLQDTLYVCPETCPKGLANGPCG
GTRLNRCEFGDRECVHSVKYRIAKSADQLAVLAQTLIPCIEADNRHRSSWPEWFEPEDTT
QGAESNPREWKPARRPLRRRK
>A0A1H8MHB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. yr461|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKTRDIQDFEHFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHTYSQQILACVMPLTLARANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKELGFAGIHLSACHKPEEQMLLESYIEQYRHLELKVLEELWNSLWQVT
SGKEFLPEIARFSRQPTSKQLIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENALVAK
VLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKALEQTDVLKEKLIPTVAIETRGTSSWKNWYLATED
>E7S068|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lautropia mirabilis ATCC 51599|TrEMBL
MTRQAPSLSFEFFPPTTDAGAQKLLETHRALQALQPEYFSVTFGAGGSTQARTAEAVTNL
TAAGSEVAPHLTCVGATRDSIRELLDGYRAQGVKRLVALRGDLPSGTMSLGDFQHASDLV
RFVREHSGDWFTIEVAAYPEMHPQATSPDTDLAHFAEKVAAGADSAITQYFYNADAYFSF
VERARAAGVTIPIVPGIMPILNYTQLSRFSDNCGAEIPRWIRLRLAAFHDDMDSLRAFGH
DVVVDLCDRLLAGGAPGIHFYTMNQAGPCAAIWQALKR
>A0A2E3HLW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium|TrEMBL
MSPTMDQMREAQRALEAPLFSGLPGDIDVSFEFFPPKNAAMNETLWQSVETLAPLGPRFA
SVTYGAGGSTRERTHQQVVRIQNEARIPAAAHLTCVEATREEVDEVARHYWDEGIRHIVA
LRGDAPDGQSQYAPHPGGYANAVELIAGLKRVADFEISVAAYPEVHPDSPDRQADLDNLK
AKFDAGATRAITQFFFDPQCFFDFRDRAAAAGIDGEIVPGIMPVLSFAAVRRMSGLCGTA
IPPWMEGLFDGLDDRPAARQLVSATIAAELVRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRAKAGR
>N8WME5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 102082|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLHIVHQELQRLNPEFFSITYGAGGSTRERTLATIHDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGNHFHIEVAAYPEMHPQADSFDADIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERLEKEGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1M6DR51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatibacillum alkenivorans DSM 16219|TrEMBL
MQLRDKSEAGQFIVLAEMEPPKGVDVTDFTANAIRVKDQVDAFVVPEMNSAVMRMSSLGA
SLILQSKGLPTVMQVNCRDRNRLGLQADLLAAGAIGVQNVMAVTGEDPSFGDHHQASAVY
DIDLIELLKAVRGMTQGKDMAGVDLAGAPSFYCGSTVNAGVKGKALQLEIDEMKRKIDAG
AKFFITPPVFNMSDLSDFMEKAPRAEVKVLPTVLLLKSVGMARYIDRHSDHVSVGDALIK
RIMSASDKGRECAQIAADTIQAAKNAGLDGVMIATLGWEHMLPQVLNLKPTEAQDVEQDD
PNTSWGKHAGGK
>A0A2M8HNF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira sp|TrEMBL
MAEHISEILKSNNPCISFEFFPPKTQESSDILFHTISELMPLKPAYVSVTYGAGGSTSEL
TRELVVKLQRETSLSIVSHLTCVGHTKEEIRSLLKIYDESGIRNIMALRGDPPHGQKEFV
PVPNGFHYAAELVAFIKKEFPSMGIGVAGFPEGHPVTPNRLLEIDYLKRKVDEGADYICT
QLFFDNRDFYDFRERCELAGIKIPIIAGIMPITSRKSINRMAELALGSKFPAKLLKNLTR
AVDDTYAENVGIHWATEQVRDLLDQNVKGIHMYTLNRSKATLQICHSLGIESFKNLETKN
>A0A0S8KN23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium SM1_79|TrEMBL
MKSGSRLEKVLTADKFAVTAELGPPQNANPEAIKKKAQYCLNNVDGANITDNQTAIVRMS
SIAAASIAISCGVEPVVQMVCRDRNRIAMQSDILGAAALGVKNFLCLSGDHQKFGNHPQA
ANVFDIDSMQLIAMIKKMRDDKQFLSGDAIKEHEPRLFIGAVENPFADPFEFRVLRLAKK
IEAGADFIQTQCVFDVDKFSKWMELVVEAGLHKKVYILAGLTPVRSAKALIYMKNEVAGM
SIPDELIKRMESAKEPKEEGIKICLEMIESVKKIDGVSGIHLMPIGWESITPVILERAGL
LPRPQV
>A0A2J6SPI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyaloscypha bicolor E|TrEMBL
MEKITTKIAALPPGTPYFSLEFFPPKTPMGSSNLRARLDRMSHSLRPLFVTVTWGAGGST
ADRSMELAELCQRELGLTTCLHLTCTNMKRDMVDRALEDANALGVRNILALRGDPPRSDY
KDGNGNGDGGAEGEFEWAVDLVRYIRKGYGDYFCIGVAAYPEGHADESHPEGQSLEHDLP
YLVEKVGAGADFIMTQLFFDIDAYDRFEQRLRDHESGLFKTLPIIPGMMPIQSYQMIKRT
TKLSHAKMPSKIMERLDVVKGDDEMVKKVGVDIVSEIVTHIKNSPSPQPRGFHFYTLNLE
KAVSFILERTKLIPCSPTDIECAITEEPLPLPLPLQTVSINGPHTNDSRHRRTRRQSSVG
SDPHNRIIITAPRTSNPSYEATGLEAGVPAEPVNTRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGYPTSRDDITDLFFRHIEGSLSAIPWNE
EGLNEETNTIKSQLLKLNQKGWWTVASQPAVNGVRSTDQVFGWGPRNGFVFQKAFVELFI
PSSDWKILRQKLSEENISSMVSWYASNAAGDYLSSDTSSSSSSSSNSGNGSTNAVTWGAF
PGKEIITPTIIEEVSFRAWAEEAFGIWGEWGRVYGPGEKGQVSRGLIEGIKSDVWLVNII
HHGYVEKEGLWSMLLD
>A0A2D8VC56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MAKGRSIREFLEEGKPLFSVEFFPPRDEAGGERILATAKSLAPHQPDFVSITYGAGGGTR
ATTMRYARILREEHGFEVMPHLTCVGHTRDELLEILDDFAEAGFCNVMALRGDPPKGETE
FKAVSGGLRYGSDLVTLVRERFPHFGIGVGGYPEKXPXAPDMATDLXHLKTKVDAGADFI
TTQLFFDNRDYLDFVAACRNSGIEIPVLPGLLPVLSLGQVERFCTMCGTSMPGGLRRELE
AEDKKDQPKVGARWALEQVRGLLREGAPGFHLYALXQSASTLAILEGLKGD
>A0A239KH78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas laterariae|TrEMBL
MSVSIAQMEEARRALDAPLFADLAGDCQVSFEFFPPKTEKMEETLWNAIETLAPLNPRFV
SVTYGAGGSTRERTHATVARITRETSIPAAAHLTCVDASRDEILEVAREYWAAGVRHIVA
LRGDPPRMGEKFVAHPDGFENAAALVAGLKSVAPFEISVAAYPECHPDSADLVADLDNLK
RKIDAGANRAISQFFFSPEAFFRFRDAVEKAGIDAEIVPGILPVSNVAQTRKFAGMCGAA
IPPWMDRLFEGLDDHPAARQLVAATIAAEMCRKLYAGGVRHFHFYTLNRAELSYAICHLL
GLRPEQVAAERAA
>A0A2S6ZBE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas theicola|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQASDALLDLRHFKAKVDAGADAAITQYFYNADAYFHFVDA
VRRLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQALGDDADAIREFGADVV
AALCERLIAGGAPSLHFYTLNLAKPTVGVLSRLA
>A0A7K1NNR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. GA104|TrEMBL
MMFPIRIEIIPSEGIVEQVQALVPRSTTLSVTCLPHHGIERTMRTAVEAADLGYTVVPHL
AARSIRSRAELTEIIRGCNAAGIGEVFVIGGDRKQPAGTYDSALPVLEDIAQYTGGTMRA
GVAGYPEGHPVASPLDLLDGLLAKQHLASHVVTQMCFDPGRIHDYAALLRREGVRLPVWA
GVAGSVPRTKLVALATQIGVGSSLKFLSRKGPLARKLLSGDRYSPDSLITGLATQPGNIA
GIHLYSFNSLASAPDYGVHPAPEQASPSAALHPALIRGAARDH
>A0A832B4F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MDGLGGAPRISVELWPPRSPQAAERLEASLDKLAELRPSFASITYGAAGSTRERTHDLVV
EMEGRRATTAMAHLTCVAHSRAELVGILRRYRDAGVENVLALRGDRPAGGSTAHVEGELE
HAVDLVELASTVGRFCIAVAAHPAGHPEAPDVATDRRHLAEKLRIADFAITQFFYAPEEY
LALRDDLAALGVDKPVVPGVMPVTSARTLERMASLSGNPVPEWLRDRIARAGSDAQLSRR
AGVEVATQLCSRLLECGAPGLHFYTMNDVEATLEVASALGLVPAGDIGVERRLPESSH
>A0A7L4E1D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hirundo rustica|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7K2WMP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID3212|TrEMBL
MAFGTPSTRTDHAPTVRDLLAAGETTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATERIAADTTLTPVAHLTAVGQSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVKHPQGVRYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDTDIRHFVD
KCRAGADYAITQMFFEPDGYLHLRDRVESAGCATPIIPEIMPVTSVRMLERLPQLSTAAV
PSGLKERILAVKDDPAAVRSIGIEFATEFCAGLLAEGVPGLHFITLNNSTATLEIYENLG
LREQS
>A0A0F2NN56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium BRH_c16a|TrEMBL
MVPGRESSGRATDSIKSISKEAAQDGRITAVSITDNPGGNPALSPDALGREILDNGMDVI
VHFTCRDTNRVGMESRALQLARMGMKNILALTGDYSGKGFGGRGTPVFDFDSVILSSMFK
DLNRRLIKTGHSSIFTTGCAVSPFKYTEAETWVQYKKLERKIEAGSSFTITQLGYDVDKY
EELLLFKKEKGITIPALASLYLLDKRSARPMHAGRVPGVHVSEKLFQTVMQEWEDAGEGM
KHAIERTARLGVVLKGIGYNGIHLGGIHDSFATVGKILDRMDAIEHNWQEYVEEFREESG
KRFYLYKDKNRGAAQAESLRKEKIKVKITENCHYMFLKTAHDLFFDKGASLAPVYKRISS
RLDQSKTSWVLKKFLEDPFKKVLLSCQSCGDCGIQHVGFLCPESGCPKHTRNGACGGSNN
GYCEVNKDKLCVWVRAYQRMKKHGETDKLTCEFVPPRLWELKDTSSWINFHLDRDHQKPK
EPTAKAL
>A0A4U1CB77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter cryophilus|TrEMBL
MKIIDHIKNAKGKPLFSFELLPPVKGQSIQWIYDAIDPLMEFNPPFIDVTYHREDYIYKQ
QANGLLEKVSYRKRPGTVAICAAIMNKYHVDAVPHLICGGFTKEETENALIDMQFLGIDN
VLVLRGDARHADSSFIPTPGGHEFATDLLQHVKDHNEGKYLHEDVQSGDTSNFCIGVAGY
PEKHFEAPNLKTDFKYLKKKVEMGAEFIVTQMFFDNQKYFDFVKKCRENDIHVPIIPGLK
PISSVKQLISLPKIFHIDIPEDLSEAVQDCKNIKEVKKVGTEFMIQQCKELIAGGAPVLH
FYTMGKPEQTHEIAKAIF
>F4XDD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcaceae bacterium D16|TrEMBL
MKIAELFGKGKTVFSCEVFPPKKTSPVDSIYKTLDGLKDIKPDFISVTYGAGGSSTVNQS
TREIASIIQNQYHIPAMAHVTCVACTKGEVTELLAGLKQDGVENVLALRGDRNPNFPPKT
DFAHADELVAFIRRRGDFGVSGACYPEGHPESPDLITDVRHLKKKVDAGAQHLVSQLFFD
NDDFFRFLERCRLAGIEVPIEAGIMPVLNKASIERMVSMCGASLPHKLTRLLARYGDHPE
ALREAGIAYAIDQISDLIAAGVDGIHLYTMNNPQVAKQISDSVASIRRV
>A0A429UKR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC04770|TrEMBL
MALGTASTRTDHARTVRDMLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHRQS
>A0A520WAM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MTTETLASAVRGFSIESVPQDADRIDDFRDHVPTGTRVFIAWPPRATPESIVKSARKLHE
QEMVPVPHIAARRVPSQEFLRAFVGDLVAQAHVREVLVIGGDPATPEGPYTDTGSLLRSG
VLNELGIEKVGVAAHPEGHPVMSGAVSREVLADNLAAARDHGMSVEAVSQFVLDPQAIDS
WHAEVYSSLAQGAPLLIGIPGLVSGTRLLKIANACGIGESIGLLRKNGLRMAKTVIGNSS
TQTLVEGLAPLANRATDVGGFHFYTFGNFEQTAAWACEAASTPAAAAG
>A0A125S334|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga haemolytica|TrEMBL
MKVTEHIKRAKGKTLFSFEVIPPKKGNNIEELYKNIDPLMEFNPPFIDVTTSREEFYYIE
HPNGLFEKRITRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSREETEYLLVDCYYLGIHN
VMALRGDAMKEQRYFEPTRGGHTYASQLVKQIANLNRGKYLHEVIEADTKADYFCIGVAG
YPEKHLEAPSLQFDLARLKEKVEAGAHYIVTQMFFDNQKYFAFVDSVRQMGIDVPIIPGI
KPIATKKHLHLLSQAFKIDFPEELVHEVERCKTNVEVKEVGVEWAIYQSRELKTYGVPVL
HYYSMGKADNIARVVREVF
>A0A4Z0K5J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. S22|TrEMBL
MSITTAIPRISASAPDSAAELHPPSRRRLRRALSFEVIPPRSEKQAARLPGLLRFLDSLT
PDYLAVTSSANSGWLQGTADFIADITATTSLRPLAHLTCTASTEAELLPWIDHLLGVGVR
GFLAIRGDFPDREASLPPGHLPHADALVQLLRTVETDNVARLAAGRLGIGVAAYPSGHPE
STGPEEDLDVLAAKQRNGADFAITQLFFDPNAYARLRRRAEHAGITIPIIPGILPITDLK
RLHTMGRLSGLPVPDHLIARFDHAGDAAAARRIGLEITAEHTAAILDHDADGLHFYTFND
LSTTEELLTALDDKGVSVSSFPPPPPPRRWPPTTDSETTPQKEARS
>A0A1H5AVB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus koreensis|TrEMBL
MTFDSVRGRASEGWVTRTPSIVDRIRSSGDGRVPFSVEFSPPRDEAAEARLWRAVREFER
MGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWEKHPQGVEYAEELVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVTAYDPEQGAKPIIPEIMPITSLGSV
RRMLELSGSRLPAHLEKRLATAAGDGPEENRAAVREIGIDLATEMSERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSGVADPAPVTPAPVS
>A0A7C6WBF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mogibacterium sp|TrEMBL
MKISELLKQNTPLLSFEVFPPKYETAFESVKKATEEIAELRPSFMSVTYGAGGGTSKYTL
DIAKNIKDRFGVPSLAHLTCVSSSKETVKERIKEIQAAGIENVLALRGDIPEEMQGMDRS
NWDYNYAVELVREIKSTGIDFCIGGACYPEVHPESLNQKEDILHLKQKVDAGCEFLTTQM
FFDNNLLYNFLYKIREAGITVPIIPGIMPITNAKQVEAAINMSGSFMPQRFKSLVDKFGS
NPDAMKQAGIAYATDQIIDLYANGITNVHVYTMNKPDVAEKIQSNLSNILGK
>A0A7C5X119|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidilobales archaeon|TrEMBL
MAGCVGTRKVYSELMRELLSGKFVYTAEIEAGKTSNLEKIVEKGKMLKNYVTAINVTDNP
GACAHMNSLIPSYIIQRDVGVESVYQITCRDRNRLAIISDLLAAAALGIKNVLAITGDHI
TLGDNPGAKPVFDLDSATLVYLIRKMVDEGVDLAGNKIEGEVRFHVGIVANPNAVPLELE
ILKIARKVELGIDFIQTQCVFDIDLAKEFLREVRKYNIPVLIGICPVRSIGMMKWYIKEC
PGGIRIPLDIQERLKNANERKGKKGVLEESIEISTELIKELRRTTSASGAHIMAIGFEHV
IPEIVKRSAQ
>E3MN18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis remanei|TrEMBL
MTNAGGTHVAETQETIKKIDSLSTMPYCGIDTDDNTGVEERATLETGKSWSPKHYELLHE
RIERLIDEKQPFFSLEFFPPRFVNGVPNFLERVERLSEGGSVFVDMTWHMGSDPANIDKV
TSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPGTEL
QDTHQFRALDMIRWIREEYGSYFSIGCAGYPLGHPQAPSYKADLMYLKAKCDAGANFVIT
QLFFEPETFEKFVRDCREIGITQPIIPGIMPIMGYESIKRIATLSQLEIPQHILDDLEPI
KHDDDAVQKYGTERCIAMCRRLLDNGSAPSIHLYTMNREGSIREILKALGLWKLEGDRVF
PWKNRSQHPIRCLESVRPIYWSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLS
NLTVRFSKCDYSCTITFQTLRNGDDRLSMFGDNIDSIEDVKRVFINYITQTPNAAGKKVT
VLPWTEAETGVQPETSLISEQLVWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQ
KAYLECFMTAELSEKLIQIIQRDFPIRVNYHAIDKDSTFDQTNSEETTPIAVTWGVFPGS
EIAQPTVVDPLSFRAWRDEAYQMWMAQWGDFYPKESKSYGVIKSIHDTFRLVTLVDNDFQ
KPSVLFDVLQTALEELRK
>A0A8F5TBJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morganella morganii|TrEMBL
MPGAEKSFNYAIDLIRYCRENFREAEIRAAIYPDFHKETVSPAEERYWIKEKAVFGIREF
ICQFCLNSDAISYLKQTGGHDIRIVPSLFPLVNFSFIEKFTKANGIGYPSWIRKTISDPS
LVSVTDEGIALTRFFIRSALSESGRLHLFTLNNPDLLKKIFSEIE
>A0A520EZX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp|TrEMBL
MTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSVAELRSMVGSYADRGITNILVL
RGDPPGDPLGEWEKHPEGVEYAEELVRMVRELGDFHVGVASFPEGHHRADDLEQDTRCLV
GKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSVRRMLELS
GTTLPSHLDEKFTRAAGSGAEEDKAAVREVGIELATNIGERLIAEGAPGLHFITLNFARA
TREVLSNLGLAAARV
>A0A8F5Y5V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morganella morganii|TrEMBL
MFRSTTSTVNFPEKRPFTLQIALREITWFKKEGWKTGRKYVRNGYNQAEGQNIFLFYGVF
TERENRGIMNGISFEINAVSENNNGVELLKSLIEFTETLNPLFYTVNTEIGMMPQAATFD
TCMVLKQYTGKKIIPHIAINNKDECELDCILSRYINAGISSFFLIRGG
>A0A6A3BRB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hibiscus syriacus|TrEMBL
MNPLSQRLLKIVDGLNFKDFVPFLSAFSAKAIIFKVYDSDGNGKESFNDILEVLRDLSGS
FISDVKRMMQAHMNKERACVMLCICMQLMHVQIRLKMNVIEKIQSSPQDLGKVVFSFEFF
PPKTEDGVENLCERMDRMVAHNPSFYDITWGAGGSTTDLTLDITNKVKNIICVETMMHLT
CTNMSVEKIDHALEIIKSNGIHNVIALRGDPPHGQDKFVQVEGGFACALDLVKHIRAKYG
DYSCITVAGYPEANPDAIGDNGVATPEAYQNDLAYLKRKVDAGADLIVTQLFYDEITAAL
EPIKDNDEVVKVYGIHLGTKMCRKILANGIKTLHLYTLNMEQDHILKANGMVNC
>A0A176XT61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MSESISPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLRDILQAYKSEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQATNPSADLAHFVSKVKAGADAAITQYFFNADAYF
DFVDRARAKGVNVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHSEAPLAIWKELTV
>A0A522TSX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp|TrEMBL
MPSISFEFFPPKTDEQRAQLDHAAQVLKAYQPEYASVTSGAGGSTLSYTGDTVARLHTHH
GLNVAPHLSCMGGTRAELAALLDDYRAAGYRRLVALRGDMPSGMATSGDFRYAAELVGFI
REHCGDHFHIEVAGYPETHPQADDALCDLRHFKAKIDAGANGAITQYFFNPDAYFRFVED
VHKLGVEVPIVPGIMPISNYSQLKRFSEMCGAEIPRWIAKRMQAHGDDVDSVRELGAEVV
AQLCRRLLDGGAPGLHFYTLNRARATQAVLRQLS
>A9DE18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea phototrophica (strain DSM 17068 / NCIMB 14078 / DFL-43)|TrEMBL
MPSSPRASAEDLSDRIKVSFEFFPPKNGDMENQLWESITKLAPFQPDFVSVTYGAGGSTK
QPTLKTVSRIASETSLAPAAHLTCVGSDKASVDAVAREFKSVGVKHFVALRGDPPEGVGA
AYQPHPEGYANGAELVAGLRAIDDFEISVSAYPERHPESPDFATDIDMLKRKVDAGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGILPIHNFGQVARFSKLCGTSIPDWLARRFD
GLEKDPETRALVAAAIAADQVTDLVERGVDDFHFYTMNRAQLVYAICHLLGLRSGETPAV
GAAA
>A0A424WAR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MSDSTTPAFSLEFFPPRDLAGQERMVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCEAAPHLSCVGATRQDLRDILQAYKNDGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVNKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVNVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPLAVWKELAVQA
>A0A423DP13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas chlororaphis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAGYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLSQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLFNFVRKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3S4RQ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium aurum|TrEMBL
MTQGCPKRMDFGPCGGVRPDGQCEMRPGDCVFPEAVLWAGPVVDAPAVQPPLILTDFSCT
PFDPADVESVATTLAPSCDAVLVGEHQNRPDFPPTLMSRMLLDVGATPWITLSCRDRNRI
VLEQELRGLALLGVGTVFCVTGDGRGYDVRPDVTQTFDLDGPRLVALSASLGMAAAVPET
PTAPPLAARPVRLVQKQRAGASVAVLNHVTSPESVERFVGAARAAGLTIPVLAAVAVFTD
AVSAAVLQGLPGLELDADIVDRVLAAPNPIEAGIDAAVAEAQALLQIDGVAGVNISGSAS
SGGTRLGAEIKAEVGARIRAAA
>A0A2T6LZT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. GV027|TrEMBL
MAYAQIHPNWDKEPAGITDGYSLEMTAKDIASLREAAPLIPPETPVAVTYLPGEEAQARI
AATVAVRELGFEPMPHFSARRIIDVPEFEAYLQAVVEQAGVRRCFIVAGDPAEPQGPFFD
SSALIATGAFERAGITAIGIGGHPDGHPNMTEAECWAVLDKKVAEITARGMAPLIVTQFG
FDADSFLVWLEKLRARGIDAPVRIGVPGPAGIKRLLGFAARCGVGASASVMKKYGISLGN
LLGSAGPDKLVDAFASGLGPQHGRVRLHFYPFGGLAKTVEWIEDYRRRHPA
>A0A228QKL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. HI2761|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAAVATRTICERLAV
>A0A0D5XT07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas chlororaphis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLSQYQAAGINRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVQQMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1W9WRY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_89|TrEMBL
MKLTTLFNHDKFVITGEVGPIKGAIHRDKSIEPSCAIEALHLHQHVHAVNVTDNQSAVMR
LGSLASSVRLKTNGVEPVYQLTCRDRNRLALQSDLLTAYSLGIDNVLLLTGDHIQLGDHK
EAKPVFDLDSVQLIEMAQGLKRGYDISGNRIENYIDMAYGAVVNPNSDPLELQLMKMKKK
IDAGAQFFQTQAVYDVRVFEKFMNMVEKYNIPIQVGVVILKNPQMGRFMNKNISGIHVPD
EWIEEIGSVDKEDRKKKAAEMTGTFIRKVKSMIQGVHIMPLGWTDIVPDILEHAEISKDA
>G9PFL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces graevenitzii C83|TrEMBL
MHLCEGTVTNTKVSIVPFSNDIYACPCTHDHEPTLLSFEVMPPRKPSLEAPFWQTVDQLL
QVRPDFMSVTYGAGGKDRSNARATVHRLVADTPIQPIAHLTCVGNSTAEVVSTVYDYLDS
GVRTFLALRGDPPAGETSWEPGPDGVASATELIHLIRTVEQRRCEAHPGEALRSAFKPLT
IAVAAFPAGNPAAGTTPTQEVERLLVKQAAGASFAITQLFWNAEVYASFVERARRAGVHI
PIVPGILPATDPARLRRVQDLTGIEVPEHLLSTLAGYQHQEQRDAFGAAFGSKLIHSVLE
AGAPGVHLYTFNKAKPVLDILSLMGVEPTAHHSPLLAR
>A0A4V2SR54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum marinum|TrEMBL
MSAAPRVSFEFFPPQSIEASFRLWDTVQALAPLKPQFVSVTYGAGGTTRKLTHDAVETIH
KHYGLNVAAHLTCVEATRAETMEIVDSYAQAGVTEIVALRGDPPKGQGAFTAHPDGFANS
CELIEALAARAAFTIRVGAYPDPHPESQGVGHDVQWLKRKFEAGADSAITQFFFEAETFF
RFRDECDAAGIDGAKIIPGILPIEKWAGVRRFAERCGAHVPAWVDEAFDKAVRDGREELL
GKAMATELCSKLMEGGVQDFHFYTLNKPHLTRDICHALGVQTQAHLEKVA
>A0A7V9EID5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKPTGVLAELLTRPRYEVIPLAGAEEAVLEHVPTEVKVTVTTSPRKGLEPTLDLVEKVAA
HGYTVVPHLAARHVRDTVHLAELVERLRATGATDVLVLAGDAEEPAGEFDGSLPLLRALA
ELGQQFHDVGITGYPESHAFISDDATINSMFAKEEFATYIVSQICFDPKVTAAWMAAVWE
RGTKLPIHIGLPGPVPLTKLVRVSARIGVGDSLRFLRTHKGWLGRAFSGAFDPTPLVEGL
DASLADARPNLAGFHVFTFNDLEGTEHWRQRHLEVLGTMRQTGSDSASETASSSVRSRPS
A
>A0A7V9G0U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSRLEEAVRAGRLVLTAELLTVDSGGLDAVHERFAPYEEWVDAVNATDNTAAHAHASPLA
VAIALKQLGMEPVMQLVCRDRNRLALEAEIAGAALHGIENICCLTGDDVTAGDEPETRRV
FDLDAIQLLVTASALAGGRYLSGRAIDPAPHLFLGAVENPAAPPVDHRVARALKKVRAGA
RFLQLQVGFEREPLERFMAQAVATGLAEQAAILPSICLVRSPKALRFVDERVPGISVPAE
LIARCESAADPEAECFEVACELADHALSLPGVRGLHLISFRREAGIARLCLRLGIATREE
REMSGDRPRVVV
>A0A7C3T366|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTLLIKEHAKPAIQEILEAGKFLVTGEIGPPKGTDIDEMIEHIKLLKDKVHAMNITDNQS
SVMRYPSLGTAILIKELGGEPNLQVTCRDRNRLAIEADLLFAYTRGIRSVLCLTGDSIPV
GDHKEAKAVFDCESVQLLQIIRNMEEGRDSGGNELKGGVKFFKGAIVTPEAVPIEPQMLK
FEKKIEAGAQWFQTQAVYDMDNFKRFMEKARKINDKVYICCGLVLLTSPGQIKYMNNNVP
GVFVPENLAREMEDAPKEERLNTGIRIMARQIRQCIDEKLCDGVHIMAIGKEDVVPQILE
EAGVDITKM
>A0A845UCX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger sp. PrR003|TrEMBL
MTRPDISFEFFPPRNIEATFRLWDTVQALSPLGPRFVSVTYGAGGTTRELTRDVVATLHK
NSGLKVAAHLTCVDATREETLAIARQFKEAGVNDIVALRGDPPKGASGFTPHPEGFNSSV
ELIEALREAGDFTIRVGAYPDKHPEAPSATADVEYLKRKFDAGASEALTQFFFEAESFFR
FRDACEKAGIDKPIVPGILPIENWKGARRFAEATSTKIPAWVIEAFEKAERDDRQDLLAT
AMCTELCNELLEGGVEKLHFYTLNRPELTRDVCHALGVVPDSKLENVA
>A0A7L8CIB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weissella viridescens|TrEMBL
MEKTIKYSLEISTPATVGEQEDLIRQLQTLPSDEIEFIAITLGAGGSIELATPVLSFIQL
LLECIKVPIVPHITGSHQTQAQVQELLRKLSGMGIQTVLAVRGDGEPNAFGHGDDLIRFI
EKTGEFEVLGAAYPEGHPEDDNLQQTIQTVERKRLAGAKTLMTQVVMDNHRLYQFQQALR
TAQVSMPLIIGIMPYVQRERVIKMIQLTQVTPSPVVQGLLTQTDVNAFRSEGLALTIKQI
VDLRKHGYSHIHLFCQNDIAVVSELFQGL
>A0A7W0SV45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
LQRKLRTGEFVVSVEIDPPRGGQAQTMLDLARTLKESGHVDVVDVNDNPRARARMSGLIA
STTIERVAGIETIPHLTPRDSSIAGLESMLLGAHAEGVRNVLAVTGDPPEAGDYPGSGGV
YEVDSIGLSRIITQMNAGEDFNGREIDAPTSFFLGVAVNPAADDLGYELERFEQKLEAGA
RFAMTQVLFDFAYLDAFLERLGRTCPIPLLIGIFYVKSHQLAFRLHNEVPGIVVPEHVLA
RLRDAGPSAGPVGLEIARELLEESRERAAGAYVIPPFRQPLAALELFA
>A0A075R317|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus laterosporus LMG 15441|TrEMBL
MGKRDLRAYLTQHVLVGDGAMATQLYEQGVPIGVSYEELCLSNPQIIRNVHTAYYEAGAR
LIETNTFGANRDSLSRYGLESKVTRMNRAAVTLAREAVGDDAFVVGAMGSIIAGRVRTKQ
IDQFKDQFEEQATSLLHAGVDGILLETFLDVDELLLALEVIRPLTELPIIAQLATLEVGT
TRDGHSLTYAFQQIKDAGADVIGLNCRLGPAEILRSFEATVCPDDVFLSAFPNAGRLGMA
DGTLSYKSSPDYFAESALRLHEQGVRLIGGCCGTTPEHTRAIAEKLAGRKPLPRVNPPAP
IHSERIEVQAVQKRLQPSIIEEVKHHPTIIVEFDPPKDLHTEDFLQGCCALHDAGANAIT
LADNSLATVRMSNMALGAMMKRLGIEPLLHIACRDRNLIGQQSHLMGLHALGIDQVLVIT
GDPSRFGDLPGASSVYDVSSFDLIRMVKQLNQGYAFSGKQLKQHAQFIVGAAFNPHVRHL
DAAVARLEKKVEAGADYIMTQPVYDAETIVQIYEATKHIRVPIFIGIMPLTSSRNAEFLH
NEVPGIKLSPYALEQMKLFTGEAARQEGNRMAKELIDATLQYFNGIYLITPFNYYQMTVE
LTQYIRQQEQVKAGLKEVSSS
>A0A6I3DQ91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSETSLIRQSNLNSLDFVAVSEVSAARKSSGEPTLSYEFFPPKDEAGEENLWASFEILME
TQPDYVSVTYGAGGSNREKSLAVVDRMAKRVLTIGHLTCVGASEAGTTEIIRRFETAGVG
AILALRGDSPKDDPDALTKGDLKTALELVELVNRETALEVGVAAFPEVHPESKDMAHDSA
VLKLKESAGASFAVTQLFFSVEAYLALVHSAKNAGVSMPIVPGVMPISNAKQVIRMAELS
GAAIPDELLAKFDSAQNDDQARKIGMDYATQLAIDLIAAGAPGIHIFTLNSHTAAIELAR
GAGLCR
>A0A7K0S2W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MKTTYSFEFFPPKDVDGEARLWKAMAALETIAPDFISVTYGAGGSTRDRTIKITSEITSR
TNIPTVAHLTCVGSTKSELLEILGRYQSSGIKSILALRGDPTGGPRAPWTSTPDGLNHAD
ELVKLAADFGGFEIGVAAFPDGHPASNGNLDIDIDVLIRKESLGASFATTQFFFEADKWK
SLVDKLAAKGSKLPIIAGILPVTNVKQLNRMSELTGTPIPSRLSGAFEKVQDNPEDVYKL
GVEVATKLSQDLLNAGVPGLHFYTMNTSNATREIYANLKVGDR
>A0A7K0XG47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDRGARAVTSAPTRLAGLARSRNQLATLASSRNRPIVTAECPSADGGTIDDLAARLATIA
PFVDAVNVTDNPAAHAHASNVSMAIALAGLGVEPIMQIVCRDKNRLAIQADIAGAAMFGI
VNFSALTGDDVTAGDEPEARRVFDLDGPQLVSVLAGMKAGTYLSGRKFTPTGDFFIGAVE
NPGAPPLDYRADRALLKVNAGAQMVQLQISYRPDQLEAFMSACVANGVAQRAIVLPSVCL
TKGARALSFMNDKVPGISVPAETIDRVANADDQAEEAYLLVRDLTAHALQLPGVAGIHIT
DFRHDGSVQRLTEELRIGPRFDSTIAETGTNPEHEERHAHSS
>A0A7K1C083|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MERMTVSVEFFPPKDDAGEARLWEASTALESISPDFISVTYGAGGSTRDRTVQITKEITK
RTGRSTVAHLTCVGSTKDELIEILGQYKSAGIKSILALRGDPVGGPAAKWVSKPGGFDHA
DQLVELAMGQGGFEVGVAAFPDGHPASDGNLTKDIDVLLSKEQLGATFATTQFFFESSKW
ETLVSELAKRGSALPIIAGILPITNVKQLQRMAELGGTAIPVQVSKLFNEIADDPEAVKR
AGIELATNLCNELIDLKVPGLHFYTMNSSPATLEICTNLGLTNRE
>A0A3D9IWD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella lupini|TrEMBL
MKPDLRTALALKPRVGDGAMATYLYQLGLPVGVSFEEFNLLKPDVIADVHRRYAAAGAEI
IETNTYSAQHNKLSRYGLEKKTEEINAAGVAIARRAVGLEAYVVGSIGAVRGGAGKNVRT
AVVKRDFEEQVGALLAAGVDGLLLETFFDLEELSLALSIIRKKSDISVICQFAVEDAERT
HDGTPLPEAFRRLKGEGADVIGFNCRSGPNGILRALETIPRDLGVPLSVFPNAGIPDYVD
GQVIYSATPEYFASSAIKFANAGARLIGGCCGTTPEHIAAIASALQSYTPQALPDASFAA
PSAPAIEIVGSAAIADLNDSPPQAVEPSIVDLVRERHTVIVELDPPRDLDIAKFMAGAQA
LKDAKADALTMADNSLAVTRMSNMALAALLNERIGIKPLVHIACRDRNLIGTQSHMMGFD
ALGIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFIV
GAAFNPNVKHLDKAVQRLERKISAGADYIMTQPVYDPELIERIAEMTKHLNVPIFLGIFP
LASGRNAEYLHNEVPGIQLSDSVRQRMSGLEGPAGRAEGVKIAEELLDVAMAHFNGIYLM
TPFMAYEMTVSLTEYVRERSGSLTSSK
>A0A1G8CPL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aneurinibacillus thermoaerophilus|TrEMBL
MPKESLKTYLKDHLLIGDGAMATWLYQLGIPIGVCYEELNLSNPELIRAVHRSYYEAGAR
FIQTNTYGAHRDALARHGLQDKVTRINRVAVQVAREAVKDDAYVVGGIGSINAGRVRDVR
MQNYREQFEEQAAALLMGGVDAILLETFLDLDELLLALDVIRPLTDVPIVAQLATIEVGR
TRDGHTLTRAFAELKKAGADVVGLNCRLGPAEILRSIENAVVPEDTPLSVFPNAGRLAMS
DGQYSYASVPQYFGENALRFRAQGARLIGGCCGTTPEHIRVMAQVLAEREPLPRVNPVVD
TQEEAEPLIRIAPPARKQGIVETVAHRHTVIVELDPPRDLDTEKFLRGTAALQDAGADAI
TLADNSLATTRMSNMALGSIMKAKFGAEPLLHIACRDRNLIGQQSHLMGLHALGINQVLV
VTGDPARFGDLPGASSVFDVSSFDLIRMIKQLNEGYSFSGKPLKQRANFVVGAAFNPHVR
QFDAALRRLEKKVEAGADFIMTQPLYDRESIERIYEGTRHLDIPIFIGIMPLTSSRNAEF
LHNEVPGIRLSDEARTRMRRYEPGEEARREGVAIARELVDIAMEYFKGIYLITPFFYYEM
TVELTRYIRDRSRVVLQK
>A0A7V1YJI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDRRPPRPGGRVARGGAGGGGLSRASLLGDAAAERVLTTSCGPLRRADASELRARLGALR
GAFRFVKFGDSPRGVASVSPWAAACLALQEGFEPVVHVACRGRDRVSLRAELLGGRVLDV
RHLLCLRGDDPPGGQAFREVDVLELLAMARGVDEGWTLLAAADPGLEPTPAVLGRLRAKV
AAGAALLETQPVFDVGAFAGWLAAVRAAGIEAPVLVDVFVLSGPEEAERVARIPGVGVPA
AVRRRLREPGGGVRVAAELVGELRGLPGVIGCHLSTFRGDVELVLAVAEGLR
>A0A023DE94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parageobacillus caldoxylosilyticus NBRC 107762|TrEMBL
MGLLQDLKERILIADGAMGTLLYSHGVDRCFEELNLSKPEEIIHIHEAYIAAGAEVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLAKQAAGNKAYVLGTIGGLRSINKSAVSIEEVK
RTFREQLFVLLNEDVDGLLLETYYDLEELETVLAIARKETDKPIIAHVSLHEVGVLQDGT
PLAEALARLEQLGADVVGLNCRLGPYHMIRSLEEVPLPNRAFLSAYPNASLPDYRDGRLV
YETNTDYFKETALAFREQGVRLIGGCCGTTPKHIEAMANALTDRTPVQTKTVKQRHISVS
ISSNEPNAAPPLQDIVRERRSVIVELDPPKKLGIAKFLEGAKALKEANIDALTLADNSLA
TPRISNMALGSIVKQQLGIRPLIHITCRDRNLIGLQSHLMGLHALGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVER
LEKKIQCGAHYFITQPLYSERQIEEVYEATKHLETPIYIGIMPLVSARNADFLHHEVPGI
TLSEEIRARMAACANDPVQAAREGIAIAKSLIDAAFDLFNGIYLITPFLRYEMTAELVRY
IHEKEKAAQERKVLHG
>A0A7V9D6S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTSAEGRNTIQRWLDLARYEVIPLEGAEERVLQSVGKEIKVTVTASPRRGLDPTLELAER
LARHGYSAVPHISARLVADGRHLDEVVERVRAAGIKEVFVVAGDEARPEGEFSGSLELLQ
AMHERGHSFDDVGIAGYPESHPLIDDDVTIQSMWDKRQFGTYIVSNICFDAKVIVRWVKR
VRRRGVELPIYLGLPSITDTAKLLRVSQKIGVGESARFLTKSRGGLLRLVVPGGYDPTRL
LEKLAPRLGDPALDVPGIHIYTFNEIEQTEAWRRQITREARSRG
>A0A7U2MV61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus flavus|TrEMBL
MGMFPFPLIGGPVKLRPKPFPPRWISPQSSLFNYHLSRNFAGTDSGIKMEKITDKIAALP
PDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGSTAQRSLELAEICQ
RQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNRD
FTFAVDLVRYIRQKHGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTQAGADFIM
TQLTYDIEAYTRFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVQIPPQILA
KLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLRGFHFYTLNLEKTVSFILERCDLIP
PYSEDFDAIEEGGDISAMDGAHLRSLTRRRASSINSLPHNRVIVDKLHASEVSSKASVSH
EAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPS
LHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPE
LLQLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKP
LLQKHGHEKLAWFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTI
IEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNDIKDDVWLVCVVGQDFGAGTEMGSE
EEEDEKKFMWRVLLNAKK
>A0A7K0LU04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MREEGAGAGSDASRRSLGEVLSTGSRSFSFELFPPKTDDGERALWQTIRDLQGLSPSLIS
VTYGAGGSTRDRTVRIVGGIAAEPALTPLAHLTCVGASRDEVRAVVDEFAAAGVRAILAL
RGDPPGGPGSAWVQHQDGFAHADELVEFIASMGNFSIGVAAFPEGHPESANLADDAVVLA
RKQDAGAEFAITQFFFDARDYERLVRDAAGHGCTMPILPGLLPVTNVAQIERFAALSGAA
FPADLAARFALVKDDPDAVHALGVEVAAELGQKLLEMGAPGLHFYTLNRSASTLEVCEAL
GLGAR
>A0A7Y4HRY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. 260|TrEMBL
MADDPGSLPLRVEIIPAPGIVEALREHLPAPAVVTITCLAHHGAEETIDLAVRLADLGYR
AVPHLAARSLKSRGQLAGFLTRLQTAGVSDIFVIAGDGEEAAGSYAWSGALMADIASLGG
GWFSLGTAAYPEGRPGTSSSELTDLLLAKQGLCSWAVTQLCFSGPVLSTYLTELRAAGVW
LPVWAGVPGAVRRTRLISLAARIGVGPSLRFAQRSLTGAGGGSLVRSVLAPSSYDPAPLV
RSVVDSGGFAGLHVYSFNDVQSVARTFGADA
>A0A7K0ZM08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
LVRDAAGHGCTMPILPGLLPVTNVAQIERFAALSGAAFPADLAARFALVKDDPDAVHSLG
VEVAAELGQKLLEMGAPGLHFYTLNRSASTLEVCEALGLGAR
>A0A6I2VDM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MREEGAGAGSDASRRSLGEVLSTGSRSFSFELFPPKTDDGERALWQTIRDLQGLSPSLIS
VTYGAGGSTRDRTVRIVGGIAAEPALTPLAHLTCVGASRDEVRAVVDEFAAAGVRAILAL
RGDPPGGPGSAWVQHQDGFAHADELVEFIASMGNFSIGVAAFPEGHPESANLADDAVVLA
RKQDAGAEFAITQFFFDARDYERLVRDAAGHGCTMPILPGLLPVTNVAQIERFAALSGAA
FPADLAARFALVKDDPDAVHSLGVEVAAELGQKLLEMGAPGLHFYTLNRSASTLEVCEAL
GLGAR
>A0A7C2HSE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTLLIDKHVKPSIQEILESGTFLVTGEIGPPKGTDIDEMIHHIDLLKDKVHAMNITDNQS
SVMRYPSLGTALIIKERGGEPNLQVTCRDRNRLAIEADLLFAYTRGIRSVLCLTGDSIPV
GDHKEAKGVFDCESVQLLQIIRNMEEGKDSGGNELQGGVQFYKGAIVTPEADPIEPQMIK
FEKKIEAGAQWFQTQAVYDMDNFKRFMERARKINDKVKICAGLVLLTSMGAIKYMNANVP
GVFVPDHLVKEMAEAPKGEALNTGIRIMARQIRQCIDEKLCDGVHIMAIGKEDVVPRILE
EAGVDITKM
>A0A7V8XDI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGSSLPQSVPRSDVASASGVVPDLLRVSRYEVLPLDGIEEEVLTHVPSDVTLTVTASPTR
GLEPTLELTERLVRHDYDVVPHLSARLVRDGAHLTELVDRLRSVDVGDVFVIAGDAEEPH
GAFAGAADLLAGLDELGRPFERIGITGYPESHPLIDDETTIAAMFAKARHATYITSQVCF
DAAVTARWIENVWSRGTKLPVYVGIPGAVGRAKLLRASTRIGIGDSLRFLRKNGNFASRM
LRNGFAPDALVDGLGDVLASGKVAGFHLFTFNALAETERWRRERLERR
>D2MZ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni subsp. jejuni 414|TrEMBL
MRSFSFEVFPPRKDESIKNLNTILDDLGQLSPNFISVTFGAAGSINSQNTLEVASLIQEE
YKIPSIVHLPCIHSSKEKIAHILQRCKRKKIKKILALRGDVCENLQRSKDFSYASDLISF
IKKQEDFEIYAACYPEKHNESKNFIEDIQHLKTKVNVGTNKLITQLFYNNEDFYNFKQNC
ALADINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAIKYLLKEELRT
>A0A537XQS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAAPGDLVVGEPAHRPGPPCSGRLARRGRGGPRAVSGLPARSHLHRLLASGQFVVTAELQ
ATDSPDPESVYRLADLLRGSVDAVNCTDNSAAHPHISPLAAGHLLLDRGVEPIVQLACRD
RNRLALQADLVGAVALGARNVCLMTGDDVTAGDHPEAKPIYDIDAIHAIQIARIMRDRGI
YVSGRRLDRPLPLFIGAVENPFAPPHDFRPMRLGKKVEAGAEFVQTQIVFNLATMRVFMA
RSGDLGLLDRVFILPSVYVCRSAGAARYLRDMVPGIDVPDSVIARIEGVPSERQADEGIR
IALEIVLVEEAGLLPRPGAGFP
>A0A3A9A732|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium 0.1xD8-71|TrEMBL
MIQTASQSNKTSLSFEIFPPKKEEEFENIFSFLRETAKLHPDFISCTYGAGGSRAGKTIE
IASYIQKELQIDAIAHITCVGFTREDLEQNCAALKEAGVNHVLALRGDRPKDMTDEQFNR
REFYYATDLVRHLKANTALEISGACYPEKHFEAPDMETDLKHLKEKVDAGVTSLVTQMFF
DNTYFYRFLEKARALGITVPVHAGIMPITTAKQLGTTVSLSGSSVPKELADIIATYGENK
EDMRKAGIDFAVRQILDLKEHGVDGIHLYSMNKLKTTTEICEQIKG
>A0A0F4P5P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio neptunius|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDASREELARIADDYWANGIQSIVALRGD
IPPGGGKPEMYASDLVKLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPNWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPVV
>F3B9Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 2_1_46FAA|TrEMBL
MKIIDRLNEDRINISFEVFPPKTEAGFDSVIKAVDEIAMLEPAFISVTYGAGGGTSGNTV
HIASHIKHDLQVESLAHLTCVSSTKEQVHEMISTLKEEGIENILALRGDIPKETEFPIAG
RYRYACELIREIKQQGDFCIGAACYPEGHVENEHKKDDIQYLKEKVDSGVDFLTTQMFFD
NSILYNFLYRIREKGITVPVLPGIMPVTNGKQIRRICELSGTVLPQRFKAIVDRFGDDPK
AMQQAGIAYATDQIIDLLANGIENIHIYSMNKPEVAKAIMMNLKEIIK
>B7MI78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O45:K1 (strain S88 / ExPEC)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4V0WYY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTELSFEFFPPKDQPGEERLWRELTQLRSLSPKFVSVTYGAGGSTRERTIRITEEIGQRT
GLDSVAHLTCVGSTQSELSEVLDSYKRAGIKEVLALRGDPVGGPLATWVATPGGFDHADQ
LVKLTVEKGLGVGVAAFPDLHPASNGNVELDLETLLRKEEFGATFAISQFFFEISSWERL
MNQLEKAGSKLKLIPGVMPVTNVKQLVKFAQLSGTQIPAKTRARFEAVAEDEKAVRELGV
EVAAELCTQLLALSCKSLHFYTMNTAEATVKVCQNLDLGK
>A0A4R9QND1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2D.F.Ca.ET.232.01.1.1|TrEMBL
MNARQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPVHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWQREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A495KJT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 102|TrEMBL
MKVTQHIQNANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEYKE
LPSGLLQKKVVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKTETYFHPEKEGNEYATELVTQISNLNNGIYLDEDLKNSAKTNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGAEYIITQMFFDNKKFFDFVDKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMAVVKAKDNDEVKQIGIEWCTAQSKELVAAGIPVLH
YYSMGKAENIKAIAKEVF
>A0A3N8GVH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Bp8992|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLQPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAATATRTICERLAV
>A0A537Z0F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTRPPGRLAALLARGSFTVTGEIVPPKGASGDPVSEHARGLVGYVDAVNLTDNPVASAHM
SPLAGVRFVADAGIEPTVQLTVRDRNRLGLTADLLGAWALGARNVFCLSGDPVHVGDHPN
AAVVADLAVGEVIGLARRMRDDGTTLANTELADPPRYLIGVADVPFAEPYDPSRLESKLD
AGADFVTTQIVYDAERLAGWADAMRLRGLFERAKVIIGVTPLRNAKQARFMEQKLPGVRV
PSPTIAALDAAGEDAGAIGMDLTVQLVEAIQTIPDIAGIHVMAMGHDAVTRDLVERTGLF
PRPTV
>A0A524KWM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MSVIEKINNADGPLFIFELLPPLKGHSIERIYTAIDRLVEFNPAYINFTSHRNETIYHER
PDGLLEKRVVRIRPGTIALAAAVKYKYNITVVPHILCGGFTREETENVLIEMNFLGIDDV
LALRGDPQKGSRRFIPEKDGHANTFELVEQINRMNKGKYLEESLVDSSPTNFCIGVAGYP
EKHFEAPNRQVDIENLKHKIESGASYIVTQMFFDNNKFCRFRDECRKVGITVPIIAGIKP
ISALNDIKLLPQAFHVDLPNDLVTAVQKCTTDKEAREVGIEWATMQSQELIKEGVPGIHY
YTLGRSDNIARIVKGSF
>A0A553FLU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassomonas sp. M1454|TrEMBL
MSSSAGLNLIXKILRSEGVNDFHFYTLNRSELTYAICHTLGVRP
>A0A537ZPL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDRILEERRPVFSFEFFPPKTDEGQATLENTLAVLKDDRPDYVSVTYGAGGSTRDRTV
EITKWIKEDLGIEAMAHLSCVGEPTQRVIEILGELRDCGIENVLALRGDPPRGEAEWRPH
PEGLHHSVELIETIRDQFDFCIGAACFPEVHPEAESLEQDLEFARRKVDAGASFLITQLF
YDNELYFDFVEEVRAAGIAVPIIPGIMPFTQYKQIKTITELCEASIPAEMERELSERAAD
PEAVAELGVAYAALQCSDLLARGAPGIHFYTLNRSPATRAILAALRAAHPWTRAT
>A0A2M7JFJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_8_14_3_um_filter_51_11|TrEMBL
MKDESRLKQLLDGGHFAVTAECGPPKGADPGAVLRKAGLLKEKVDAVNVTDNQTAIVRMS
SIAACTVLLSAGLEPVLQMVVRDRNRIALQSDVLGASALGIRNILCLSGDHQSFGNQPSA
LGVFDLDSMQFIEAVRGMRDAGTIMGGEQLTSAPAVFIGAAANPFADPLEFRVVRLAKKI
SAGAEFIQTQCIYNMERFKKWISLAEDRGLLEKAYILGGVTPLKSAGMAKYMKNKVAGMD
IPDDVIKRMDAVPKERQRQEGIGICVETILALKEIKGVKGIHIMAIEWEDAVGEIVERAG
LLPRPKVD
>A0A537XJJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MEDGPSRPPKSGSRLERVLAAKRFAVTAEVVPPASPDPSGLIATARRLNGTADAFNVTDS
PRAHVHMASWAGAVLLLRAGLEPVMQMVTRDRNRIALQADVLGASALGVRNVMALSGDDA
KAGNEPGATAIVDLDTEAFLETLRDLRDKGVLHGGDPVDPRPPIFIGATANPFGGPMEDS
FVNLRGKAEAGADFVQTQAIFDLDAFEEWMHLVRKEWIHEKLHILAGVVPLKSAKAARFM
NEKVPGVVVPPDIMKRVEKAADAKSEGLAIAVEAVEALRKIEGVRGVHLMAVNWEDAVPA
IAKRAGLLPRPEV
>A0A3P2R9V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weissella viridescens|TrEMBL
MNYSLEISTPTTVAEQQNLIKQIQKLPADHIEFIAITLGAGGSLEEATPVLRFIQLLQAA
VGIPIVPHITGSHQTLAQVETMLQQLVNMNITTVLAVRGDGYPNAFEHGDDLIRFIKATT
DLEVFGAAYPEGHPDDANVNQTVQTVARKQLAGARALMTQVVMDNHQLYRFEQALEAAQV
SMPLIIGVMPYLQRERVESMIRLTHVTPSPEVKTWLAAEARNDFRATGTALTHLQIEDLQ
QHGFSHIHIFCQNDIASVAEILDCQPGDILSFSPDETSEH
>A0A432JWM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAHATPTTASAKRLVEGYSLEITGKEKDVVGLTEAASLIPAGTKVNVTFLGNEDLPMRVA
AAKAVKELGFVPVPHISARRIASQAQLEEFLSALAEIGATEHVFAVGGDPATPEGPYPDA
LTMIRSGVLQQYGVKEVSIAGYPEGHPDIATDVLWQHLEDKSAALKDAGLDAVILTQFSF
DTDPVMAWIKGVRDRGIDTQIRLGTPGPAGIKRLISFASRFGVGANAMIVKKYGFSLTNL
MGSAGPDKFVSDLAALFDADPSVGAVKLHMYTFGGLEATATWARDFIAK
>A0A2K4LUU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FW305-E2|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQVARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQASPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLTLETRIEHWQSQVQSLEQWTPA
WHASWQMPGLPAVTFHPPQAGWRLGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPLWATRAGAHVLHTLERNVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A0D3V8B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. IHBB 10380|TrEMBL
MKPDLRQAWENNVLIGDGAMGTYLYNLGFPVGISYEELNLTSPEVIADVHRRYVAAGAQI
LETNTFSANYDKLSKYGLESKVEEINRAGVRIARSAVGDNGYIVGAIGSIRGGKRTNVSA
SELKYYFEQHIHALLMEGVDGLLLETFYDVEELVLALSIVRKMSDLPTICQFAVEDVART
LDGYAMPEAFQIVQDSGADVIGFNCRTGPNGIMRAVETLGGQLTVPVSVFPNAGIPDYVD
GEYRYAATPEYFGQMAVRFADLGARIIGGCCGTTPEHIAHIAEALTDYVPAPIDRTSVFE
SHVSPVIIDEQPNDSGDYGNLGSEPNIVDIVKSRHTVIIELDPPRDLDINKFMRGAEALK
KAGADALTLADNSLAVTRMSNMALGHLIYDRIGLRPLIHIACRDRNLIGTQSHLMGFDAL
GIDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKANFVVGA
AFNPNVKYLDKAVQRLEKKIAAGADYIMTQPVYDPKLIASIKEATAHLSIPIFLGIMPLA
SGRNAEYLHNEVPGIQLSDEVRSRMAGLEGKEGRAMGITIAKELLDEAMKHFNGIYIMTP
FMFYEMSVELMEHVWQRTGRELTPLFRS
>A0A730PYJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. houtenae serovar 43:z4,z23:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7V6CD44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacterium geofontis|TrEMBL
MEVKTYLQKVLESGEFAVTAEIEPPKSADPELIKEKAKCLKGYVDAINITDNPRATVKMS
SLAGAVILIKEGIEPVMHITCRDRNRIAIQSDLLGAYALGIKNVLCLTGDHISLGNHPQA
KPVFDLDSIHLLSLVKALNEGRFFNGEEIKGKKPCFFIGAVENPFADPLEFRPIRLTKKI
KAGAKFIQTQIVYNLERFKKFLNLCEKLGILEKVYILAGIMPPKSSKMLKLIKENKVPGI
EVPDELIKRMESAKDEKEEGINIAVEIIERVKEMPGIKGVHIMAVGWEFIVPEIIKRAKL
YPRPAL
>A0A5P1UCP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAQSLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A7J5BE89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoclavibacter sp. CFCC 14310|TrEMBL
MFSYRPLCLLRNSVVELPRLVGAATDCTECRRTDCTEYSRTDRPECSRHGLHGMYRDRSK
MPPFCQSVAARCDRGSSRECRTSAGPRGCRPESAEPVLSPVGASSRVQNLFDVGESAEDV
RINRFWQRLLCSRCPNRTDRSKYRFCSRAAQVLCPNRTETTSPTTAPKPGPRNLRTSSAP
RCNVTSHVWRRRSDAEYDGATMTASAQPAADRRPQVARSNDAAVSTEASAEEPVAERRFS
ASRFGLSVDDAFDDGDDAADALHEPAPHVAPAWDTLPTVAAPTLSLEVFPARGVPQLRRN
VTAVRKLLKLGPDFVTVTYGAAGSRQAGTKELVTWIAQSGVPTYAHLTCQAASLCELDET
IDELLEAGVTGILALRGDARDDGSGLVLPHATDLIARVSQRAEAAGQRIRIVVAAFPTGH
PDSRDLREDAENVARKQQAGADFAITQHFFDAEDYARFLDLVAATGATLPIVPGLTPTTT
VRRLERISELSGLTPPPALAAALDAAPDAQTRRDIAVQNTVELAEKLARAGAPGIQLFTM
NDEPTALRVFDALSSSPAGALGQNTGREPWLLNTQGPALKAALH
>A0A2G8SXU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia psychrophila|TrEMBL
MKTNNFSIEFYPPKTAEGADKLRVARASLATLDPKYFSVTFGAGGSTQQGTLDTVLEIIN
EGHVAAPHLSCVGGSRESIRAILAKFKSHGIKRVVALRGDLPSGYGGAGELRYASDLVEF
IRLETGDWFHVEVAAYPEVHPQARSPQDDLQNFARKVHAGANAAITQYFYNADAYFQFVD
NARKLGVDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VSVLCERLLAGGAPGLHFYSMNQAGPTSALWQRLAST
>A0A2M9H837|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium primatium|TrEMBL
MHSPQFSLEVFPPKRNAPVGTIYDTLDGLEGVNPDFISVTYGHGTHSDRTATARIANTIR
SEYGIPTVAHLTALYSDKDVVDQALDMFDAAGVFGVLALRGDVIEGQREVGVFEHASDLV
SYIHDRRPNLKIFGACYPEGHIECSSLDEDIRNLKIKVDSGATNLISQLFYDNEDFLRFV
DKARAAGIDAPIEAGIMPVTSAKSVRNMAVKNATIIPKQLEAMLEKWGDDRESLRRAGII
YASQQINDLVAQGVDGIHLYTMNHPGTTRRIWRNVAPLFQEG
>A0A828SH89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 6014059|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGK
ARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVKTGKEFTPEIARFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAKLLLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKQT
EILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A8C0EB57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bubo bubo|TrEMBL
FGNKQNSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDKWFSLEFFPPR
TANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHM
TCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDLVKHIRNEFDD
YFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLKFMKDCQAIGI
TCPVIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRE
LLDSGMVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRRVEDVRPIFWA
SRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGE
ESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNI
NGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQNI
TNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMI
IQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A091FER8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp. SCADC|TrEMBL
MRENLFKEALLNPSVFPVTWELVPGRGAKESAQEKTLSLAKQAAESGKICALTLTDNPGG
TPAMSADFMGGEIVKLGIEPLVHFTCKDRNRNQIESQLYALDRAGVRNILVMSGDYPVSG
YGGRPAPVFDLDPIHTLRLMSDMNKGLTYPGIKGNISHQSSDFFPGAVVSPFKATEAEQM
LQYYKLRKKIDAGAQFIVTQLGYDVRKFHEVFLFMKQNGLNLPLIGNIYILPYGAAKMMN
RNELPGSVVTDKLLAELDRERNESDKGEGARILRAARMYAIMKGMGFSGVHIGGHNIKYE
QVEKIISQGEALISQWADLVRYFDYPIPGGFYYFEQDSKTGLNLDKPTTRQSRPLDATVG
LSYGFSRFFHNLMFDPGKKFYGVMKGLSGKVAGTKIESIFHKLEHWTKVVIFDCKDCGDC
ALIDVAYLCPMSQCPKNQRNGACGGSFEGWCEVYPGKKKCVYVRAYARLKKHEEEAQLDK
GIVAPCNWDLYQTSSWINFYLGRDHTSKKQNSNSSGD
>A0A8C4AF26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denticeps clupeoides|TrEMBL
MVNQVQKVDGSWQSCKSDSSGASNSGESSRESSRCSTPGPDADRADRLREKMRRRIESGD
PWFSLEFFPPRTSSGAVNLISRFDRMGFGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQTKENITAHLSKAKRLGLKNIMALRGDPLGDSWEEEEGGFSYATD
LVKHIRCEFDDYFDICVAGYPTGHPEADGYHADLKHLKEKVDAGADFVITQLFFRAETFL
SFVKDCRAIGITCPILPGVFPIQGYQSLRQLVKLSKLEVPKEIMEVIEPIKDNDAAIRNY
GIQQAVEMCKVLLDSGVVPGLHFFTLNREVATIQVLRQLGLWIEDPRRPLPWAISAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKCSKDAL
LQMWGEELTSEESVFEVFTNYITAQANLSGHKVMCLPWNDDPLAPETNLLKDELEKVNRR
GILTINSQPNINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLRKYEPRVN
YHIVNVQGKNLTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEEESPSRMIIQYIHDNYYLVNLVDNDFPLDNCLWQVIDDMFDLLDAPPEPLQ
>A0A396M402|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. AF17-16|TrEMBL
MHITDIIRKAGAEGKPRFSFELLPPLKGDGTQRTFEAIDPLMEFSPIFCSVTYHREDVKY
VEKENGLLERHTVRRRPGTVGISAAIMQRYGLTVIPHLICGGQSRYDIEDALIDLDFLGI
QNVLALRGDNLKGEHTFRNHPDGHLHASELVEQIERMNRGVFIDGEVEQCHNTNFCIGVA
GYPEKHAEAPNKAEDLRRLKEKVDAGAAYIITQMSFDSAKILSFIDDCRAAGIDVPIVPG
IKPFSTKAQLTMLPQIFHVDLPEALVETVKRCNNNAEVREAGVEWAIAQGRELIAAGIPV
LHFYTMGKTDNMVKIARALF
>A0A2A3XAB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. JB37|TrEMBL
MSSLEHPLGISFEFFPPNTDAGHDKLIHVRDELAARQPRFFSVTYGAGGSTQARTRELVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVNSLVALRGDMPSGMASIGELRYANE
LVEFIRAETGDHFEIAVAAYPESHPQAANLDKDVENFVRKMKAGANMAITQYFFTADAYF
NFVDKVRALGIEQPIIPGIMPITNYTKLARFSDVCGAEIPRWMRKQLESYGDDSEAIAAF
GTDVVSQLCQRLLDGGAPGLHFYTLNQAAPVLKIVDNLTD
>V0AL80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae 909957|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A377TKL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEARANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A2N0QHA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus irregularis|TrEMBL
HGADYFISQPVYSKEKIIEIYEATRELEAPIYIGIMPLTSFRSAEFLHHEVPGIKLSDEV
LERMKACDGDKEREAEEGIAIAKELLDTATQYFNGIYLITPFLRYDFTLQLMQYIKQLDE
ETKGVKVNG
>A0A009RAJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 809848|TrEMBL
MTLADRVHSDHDIAPLEASKSYPESIDKVLHFSGKARDIQDFEHFLEQAQTANIQNLLLL
TGDKLKEHHNGRDGQPRSRYLESVNTVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLH
KKIKAGADFIITQLGYDIEALKQVKSFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGI
VITPHMLKVLADEKQAGHTDRVYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIE
QYRHLELKVLEELWNSLWQVTTGKEFSPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKI
AKGVGRFIFKATFWENTLVAKLLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGL
ANGPCGGTTLDRCEFGDRECIHSVKARLAKAVEQTEILKEKLIPTVPIETRGTSSWKNWY
LATEA
>A0A445N1Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MKSESNLEKVLSAGHFAFTGELGPPRGANAEEVRKKAAFLKGNVDAVNITDNQTAVVRMS
SWAASLILIQEGLEPNFQMVCRDRNRLAMQSDILGASTHGIKNMLCLSGDHQSFGDHPMA
KSVFDIDSIQLIGMVKQMRDEGIFLSGNKLDEAPKMFIGAAANPFAEPYEWRVLRLAKKI
AAGADFIQTQCIYNMDRFREFMKRAVDMGLTEKCYILAGVTPLKSVGMAKYMAGSVPGMD
VPDELIERVKGAGKGKAAEEGIKIAVEQIQEFKEMEGVAGVHLMAIEWEHRVPEIAKMAG
VLPRPVV
>A0A1L0FFW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hanseniaspora guilliermondii|TrEMBL
MKVDEKITQFQEKNSFEIPSFSYEYFVPKTLQGSYNLYERIDKMHKDSNPLFVDITWNAG
GIINPSSSQKKQEISKFSGKLIPKTPQTNDIIDTTQQALNLDSCMHMTCTNMTIKEIDTA
LKKAYNSGCQNILALRGDPPRETKSDSELLEDKPNETVKKYPFKYAIDLIKYIKEKYGDH
FCIGVAAYPEGHPEEKNADKLIEYLKQKVDLGATFIITQMFYNSDLFIEWCQKVRAAGIP
EYVHIIPGIMPITSYDSFLRRCNWCQIDVPSELNDILKPVSQDDEALRNLATNYVAKMCL
KLFRSGYVKHLHFYTMNLEKGSFVILRELERLLGKRLLPLTSGIISNPNKENEIQPIFWR
SRPFTYIERKKKSKKQLIRRQSSFNDQEYKSITPVPTSSASGSSSSSEFSDIDREDIDDV
NNEHNFDSELIDDEFPNGRFGDSSSPAFGNLDLSLTQLIRQSESKSLSVWGTPTSLKDLG
DLIIDYLKGDLRSLPWCDTSVALEAKQLLRLLISLNQGGILTVNSQPKANGVPSSDPILG
WGPNLGYVYQKQYIEFLLPKKKLKDFLILMNQKNTTTFTYLISDSQDEIFIYKGDDGQSR
VMASDVTKKTDIEKSSVLKKYNDLLPDICKRMYCQCFHGCTKPTAVTWGCFPGREIVTTT
IVEKNSFLMWRDELFAIIKEWRNNFVSISKNPVSIKKEKSSKGNGKNKHSESENEPSTKK
QTVSEDDLSEKSSKAASVLDTVLDDYLLVSLVDNDYVSPGDLLLFTLLQLAD
>A0A4Z0MQX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter wooponensis|TrEMBL
MKVTEHLARANGKTLFSFEVLPPKKGENIQNLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGFLEKKTVRKRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFKPDPDGHAYAADLIGQVANLNKGEYLDEEQDDTWATNFCIGTAGY
PEKHFESPNYGADLRYLKHKVDRGADYIVTQMFFDNEQFFNFEKRCREAGITVPIIPGLK
PLTTKSQLTMLPRSFYLNIPEALADAVHHAPDNAAAREIGIEWCINQSRELMAHGVPVLH
YYSMGKSESIRRVAAALF
>A0A0N1QU02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella schwarzengrund (strain CVM19633)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A319EDF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus sclerotiicarbonarius (strain CBS 121057 / IBT 28362)|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLGKVDAALQAAYKAGCTNILALRGDPPREKEA
WEATDGGFRYAKDLVDYIRSKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGASF
VITQMFYDTDNFISWVKKCRDRGISVPIIPGIMPIQTYAAFIRRSNWTKVRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELDLMPSEETP
IQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSIRDLTHIFVSFLEGKLTRLPWSDTPITTEANAIKESLVE
LNKKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLLDELIARIDKNG
DLTYHAISKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQGVMDSWYLVNIVNNDFHNTSNLFDLFKDLDVQDLDTEIPVENGEPK
AHTNGAANGTTNGVPNGAAPETAVKN
>A0A435NRP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.15.1.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A8H7YHP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Histoplasma ohiense|TrEMBL
MEKISDKIANLPTDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTWAVDLVKYIRRTHGDYFCIGVAGYPEGHSDESYPEVRDPVKDLPYL
IEKTRAGADFIMTQLTYDLGAYKRFEEMLRNHESGVFETIPIITGLMPIQSYHILTRTTK
LSHARVPPDIMARVEAVKSDDEEVKRIGVDILCEIVNGLKQVSYPGPRGFHFYTLNLEKA
VALTVEKCNLIPPLSPFPSDSETYMDTAVFMAQDKQNGISLLSKRRASSMNSQPHNRLIV
DRPSDAGGSSQASTTHETPALGAGMPALNPPPRTTTLQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVNAAVARRLWGYPTTKQDINNIFQRHVSGELHLVPWSEGGA
QDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAF
VEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSSPATDATTEDSSGPVDVFLD
SNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIFPRGSPTER
LLDQLKNDVWLICCVGQKYGAGCASSEAAEAEGKLLWKLLGGTDSVNNH
>A0A6B3C954|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID12501|TrEMBL
TEKGERNLWNALRRIEAVSPSFVSVTYGAGGSTRGGTVRATQQIAADTTLTPVAHLTAVD
HSVAELRHVIGQFADAGIRNMLALRGDPPGDPMAPWLKHPEGVDYAADLVRLLKESGDFC
VGVAAFPEMHPRSEDWDTDIRHFVDKCRAGADYAITQMFFDPENYLRLRDSVAKAGCDT
>A0A8J6ZHU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Quinella sp. 2Q5|TrEMBL
MGRIAVEIIPRDEAGLRADIDVIKKYPQVDCVNIPDLMSFTLKSWQAAEFTQPALPTIPH
VRAMDIDLAKPLPMRDDFIRFGIREVLIIAGDPPKDLTRTVYPTETIDVIRKFRDELPDV
KVYAGIDQYRSGIRDELYRVERKAQAGAVGFFTQPFFDMRYLEMFADLLDGHEIYWGVSP
VLSSRSRGYWERKDKAVFPKNFLPTMDWNIAFAKEVIDFISTSRGGLYFMPITIDIADLL
PKVFD
>A0A1D6GER4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zea mays|TrEMBL
MPVEKIDHALETIKFNGIHNVLALRGDPPHGQDKFVQVEGGFACALDLVQHIRSKYGDYF
GITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLKRKVDAGADLIVTQLFYDTDIFLKFVN
DCRQIGITCPIVPGIMPINNYKGFMRMTGFCKTKIPSEITAALDPIKDNEEAVRAYGIHL
GTEMCKKIIASGIKTLHLYTLNVDKSALGILMFTRPRGRGKKLQEEWAVPLKSVEGISER
FTNFCQGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLTINSEPA
>A0A355WLN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTTPSVSFEFFPPQGLEASFRLWNSVNTLAPLDPAFASVTYGAGGSTRDLTHEALGTLIR
QYGLNVAGHLTCVNATRQETLAIAKRYADLGVTEIVALRGDAPKGDAGFQTHPDGFASSV
ELVAALAETGDFRIRVAAYPDRHPEALDANSDIEMLKLKFEAGADSAITQYFYDIDSFLR
FRDSSATAGITRKIIPGILPIEDWEKTKRFSARCNAALPFWMDDAFAKATRDGVHDLLAI
SVATELCSDLMDEGVEDLHFYTLNQPHLTRNICKALGIEPVQSLQKVA
>A0A545TXK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denitrobaculum tricleocarpae|TrEMBL
MSASTQPQNSATSDNERIIFAPADKIAKVSFEFFPPKTPAMEQKLWSTIEHLRPLAPCFV
SVTYGAGGGTQAQTLETVKRIRNKTDLEPAAHLTCVGASRGEIDDVARAYWDAGIRHIVA
LRGDPPKTDGRYHPHPDGYAYASDLVAGLKRVANFKVSVAAYPEVHPQADSAAADLDNLK
RKLDAGAHQAITQFFFNPDDYLRFLDRARAAGISQPIIPGILPITNFERTVEFAKMCGAK
VPDWLAALFNDLNDEPVARGFVAAATAVEQCRYLQTRGVEEFHFYTLNRYELTAAICRML
RTPGLDRVTEAKKNTQDEARL
>A0A2E7PYM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutales bacterium|TrEMBL
MNSGTSIRGLFEEERPLFSVEFFPPKNEEGGERMIRTATALQPHRPDFVSITYGAGGGTR
KTTMRYAKILKEEHGFEVMPHLTCVGHSKDELLEILEGFAEAGFRNVMALRGDPPQGESE
FRVTEGGLRYASELVALIRDHFPEFGIGVGGYPEKHPEAPDFETDMKNLKTKTDAGADFI
TTQLFFDNQAYFSFVENCRKAGVLIPILPGLLPALSLGQVQRFCKMCQAFLPPELEKQLE
ATDPQKHPEIGSKWTLNQVSELLRENGPGFHLYALNKSKSTLAILEGLSLGS
>A0A1F4C4C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_62_13b|TrEMBL
MPGASERFGTSALERCLQGGDFVVTTELTPPVSTDPAPFVARALPLKGLATAVNVTDGAG
AKAHLCSLVASYYLLKNGIEPILQMTCRDRNRIALQSDLLGAAALGIRNVLVLSGDDPKA
GDQPEAKPVFDLDSTALLSIAHRMRARRELPPGTAIAGKAGFVLGAADAPIDPPPGWHPK
SLIAKADAGANFVQTQFCMDMDVVRRYATRLLELGIAQRLPILIGVCPIPSARSARWMKD
KLYGTIIPDEMVDRLEGAAEPKKEGREICIEVLRELASIPGIAGAHVMAPQNPSAIPDVI
GESGVTALKRAPMP
>A0A4V1K356|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Isolate-004|TrEMBL
MTIPELIQRKGSKGFSIEVLPPLKGKGIDQLFAGIDSLKCFEPRYINITTHRSEMVYKST
ADGLYQRVSERSRPGTVAVAAALQQRYGIPAVPHIICSGYTKAETEYALIDLRFLGITNL
LVLRGDKARHDNRFIPNTGGHAHAVELQRQINDFNNGTFVDGTTMDSANDSPFSYGVAGY
PEKHDEAPNRDIDIAWLKNKIDNGAQYIVTQMFFDNDSYFSFVERCRQSGITVPIIPGIK
PIVTKGQLTVLPKVFHVDIPTDLARAVMDCKDDVQAKEVGVEWMAMQMRGLYEAGVPSVH
IYSLNATRSVEKALRLVL
>A0A0D2AK67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verruconis gallopava|TrEMBL
MEKITDKIKALPNDANYFSLEFFPPKTSAGWVNLQARLERMSRALRPFFVNVTWGAGGST
ATKSLELAELCQQQLGLTTCLHLTCTNMNKSLIDHALEKAKAIGVRNILALRGDPPRNEE
YFDKGELEEESTEFVWAVDLVKYIRKKYGDYFCIGVAAYPEGHADSSHPERQDPLFDLPY
LIEKTKAGADFIMTQLFFDVHAYEKFEDMLRTEESGVFKDIPIIPGLMPIQSYQILRRTT
KLSHASLPADIMKRLDAVKGDDEAVKAVGVDILCEIIGELQAKKSVGPRGFHFYTLNLEK
TVSQIIERCHLLKVADDDDEDAIEIVEELSVTNGAPKPRKGRVSSAHSDPHNRVIVGKIS
GHRNSVYETLEKDAGLPSDTPTRATTLAISEGEGSMGREATWDDFPNGRWGDARSPAFGE
IDGYGVSLHVSIPQAIKMWGHPVTVGDISDIFRKHISGELAQIPWSEEGLSQETGTITNE
LLTLNKKGWWTVASQPAVNGLKSSHEIFGWGPRNGFVFQKPFVEFFLPAADWTSLKKKLE
QLPDEITYFAGNAHGDFESSDLKSVNPVTWGTFPGKEIITPTIIEAVSFRAWLEEAFSIW
REWQHIYPPKSATAKLLGDIRNGYWLVNVICHEYRNKDLLWTVLGDE
>A0A4U7KW80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporisorium graminicola|TrEMBL
MANGADSPLPPKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADL
GPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGC
RNILALRGDPPAGQSEWEPHAAGFTRAQELVQYIRENYGDYFAIAVAGFPEGHPEAVDGA
EKELQRLKEKIDAGADFIFTQMFYDFDIFAKWVKDVRAAGITCPIIPGVMPIQTYGGFQR
ATARFGTLVPKYFHDALDPVKDDDQKVREIGTRLVGEMCKKIVGTGLGISGLHIYTMNLE
KGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRRDEKIRPIFWANRAKSYVNRTETWDEFP
NGRWGDARSPAYGDVDAYGVKLRYSNDEAKEMWGAPTSLEDVKALFENFCAGKVKALPWS
ETPVARETSVISDKLTKMNQLGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEFF
VSPEDLDALIARIEADPQITYHAVNAQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVES
ISFLAWKDEAYEIGRNWAKVYEPSSPSRKFLEDMFDSYFLVNVVHNDFKAADSIFEPFLS
ASKATNAVNGSLSGLGAAVSDAAGRVAESISSLTNGVSHGNNSAPAPTA
>A0A5Q2P434|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loigolactobacillus bifermentans|TrEMBL
MSLVDKFNEKTVFSFEVFPPRSTTSAEKLYQTLTDLQAIQPDFISVTLGAGGTDRYNDTV
GIADRIQNQLHIPAIAHIPGLYLNEQDVLSLLSELAAHGIHHVLALRGDAIPGKTPQGVF
QHADQLIQFIKANSDFEVLGACYPDTHKDAPDALHDIQNLKHKVDLGADHLISQLFFENQ
HFYNFREKALLAGVDVPIEAGIMPVTNKKQIERIAAVAGVPLPTKFARMLARYENNPEAL
RDAGIAYAIDQIADLVAQGVDGVHLYTMNNSEIANRIWSATASLFAASHKPATIK
>A0A7K7UJH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ibidorhyncha struthersii|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVHGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A009IHI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain 1295743)|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A2L0QZB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. PGP41|TrEMBL
MSPPSLIETHPNLSDAAPVALSYELFPPRSPAAAETLWTTIRELETTAPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIIGELLDTGVRGILALRGDLPKD
GGAPAEGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLLTRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAPELLDRMAAADSDLERMRIGVSATVDLANAALDAGAPGIHLYTFNEHQSALDVLDKLA
LPRRTRSSRRDAVAGQLAS
>A8YXQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus helveticus (strain DPC 4571)|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSEEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHRS
>A0A2N7YNC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GW704-F2|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYHPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRALLTQYKGAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISKMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>T4W4A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraclostridium bifermentans ATCC 19299|TrEMBL
MLALTGDHTIVGDHPQAKPVFDLDCVGILQTAQKLSQGTDMVGNQLKGSPEFYLGASVTP
RYTPIEIQLLKMKKKINAGAKFFQTQAVYDIDTMREFKEHTKEMNTKILAGIIPLKSPGM
AKFMNENVPGIYVPDELIDRLRSVGKENWASEGIKIAGELIQQLRDEDLCDGVHIMAIGA
EENVPAILDAAKL
>A0A0S7Z9E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium DG_61|TrEMBL
MDTAVLKSGSNLERVLSEGHFAVTVEIGPPMDSNGEIVLEKSRLLKGMADAFNITDNQTG
VVRLSSIASSVLIMKEGLEPVMQMTCRDRNRLAIQSDILGAAALGIRNCLCIAGDHQSFG
AAGKLKGHPGAKNVYDIDSIQLVAALKGMRDDGVQQGGDSLEKRPQLFIGAAWTPLGDPI
EIRPLRLKKKVEAGADFIQTQGVFDIDRFREQMKVIVDMGLHERTAILAGIIVPKNLGML
KYMNSSVAGVSIPESLITRMEHVRSSAGDDKKKAREDQEEEGIKITVELIEHVREIPGVR
GVHIQAIEWEHRVPEILKRAGLIPRPALHKGG
>A0A1C4CLY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snodgrassella sp. R-53583|TrEMBL
MSFTSLSFEFFPPRTEEGRRKLAITRKQLSQYQPEYFSCTYGAGGTTRAGTLQTITDILN
DGVAAAPHLACIGASHQEMISLLQTYKDMGIRHIVALRGDIPSGVGFGHQGLRYANELVG
LIRQEFGDWFHIEIAAYPEFHPQSRSAEDDINHFVRKCQAGADSAITQYFFNADSYFWFV
DEVQSRGVNIPIIPGIMPIASFSKLARFSETCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCDNLLQQGAPSLHFYTLNQAGLVSTICQRLGY
>A0A256GYF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella lupini|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKSEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDVKPAAHLTCVDATREEVDRVVREFAALGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPSWLAERFE
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTEAAL
EIA
>A0A1Z4EW92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Mycobacterium] stephanolepidis|TrEMBL
MTTNPLDHDASVAELQDPGSIADRLAGVQPGDVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDLE
RDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSL
RRQVELSSSTLPIALEERLLRAAGDGPEENRDEVRKVGVEVTTSMAARLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A373C039|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium AF02-42|TrEMBL
MNLREYLKTTNLITDGAFGTYFAAKYQTQDIPELANITATEKVKKIHEEYLNAGAKFIRT
NTFASNTETLQEDFAEVEKNIQAAVEIARDAVNGRDAWIAGDIGPIPVNGAEDAAAAADE
YYQIAKTFAECGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIGEMSLWDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLSVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTKEDAARLRRIKEETGATILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>A0A177ZW95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lederbergia galactosidilytica|TrEMBL
MGLLERLKKEILIGDGAAGTLLYSYGIDRCFDQLNLSKPDQVVRIHEAYVDAGADVIQTN
TYGANYLKLSRYGLEEEVTKINRAAVRLAKQAAGGEAFVLGTIGGIHGAGLHSSVSEEIK
RGFREQLYALLLEGVDGIILETYYDLDELTTVLRMARDETNLPIIANVSMHEPGVLQNGT
PLEEALKQLDVLGANVVGINCRLGPYHMVKALESVPLSKTAYLAAYPNASLPEYEDGKFI
YKTEPDYFTEFVRKFRDQGVRLIGGCCGTTPEHIQALATGRQYLTPLEEKQIIKQKPFVI
KTETIDKEPSIFEKVQSDRSIIVELDTPRHLDTEPFFRGADALKRAGVDGLTLADNSLAS
PRICNATMASLVKKKVGLDSLVHITCRDRNLIGLQSHLMGLHTAGIRDILAITGDPTKIG
DFPGATSVYDATSFELIKLIKQFNKGISFSGKSLREKTQFKVAAAFNPNVRNIGKSVERM
EKKIKYGADYFLTQPVFSLEKILEVGEATKHITAPIYIGIMPLVSARNAEFLHNEVPGIK
LPDDIRRRMAKTEGKPRQAKEEGLAIAKELIDSAFGYFKGFYLITPFIQYDLSVELATYI
QEKTKNKQKKQLLH
>A0A1M7TJL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium erythrophlei|TrEMBL
MLCPSFEIFFLYPIFYAGIGQFPILGGLFGASLFPYVGPISFGRDDSTARHPVLLRRFSK
VMSETIPAPATSRAQSQPAISFEFFPPKTAEMENSLWETISRLAPLTPNFVSVTYGAGGS
TRERTHSTIARILKETDLLPAAHLTCVGAARSEIDDIVGRYHETGVRHIVALRGDPPGGI
GTPYLTHPDGYQTSPELVAGIKKRFPDIEVSVSAYPEKHPESRNFDADIDTLKAKVDAGA
TRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTVPNWLAE
KFDGLDDDAETRKLVAATVVAGQVQKLNKHGVDTFHFYTMNRADLVFAICHLLGIRPAGA
QKAA
>A0A7V4QBZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacterales bacterium|TrEMBL
MVEQLIKKLEKSLITLEITPPKSTNLSEVLDSVKKIKKLDEIDGFIVTDNPLAKLKYSST
LASVKIASELGKPVICTMSMRDKNKLALQSDLLGLNDFGVRMVLALTGDPANISDQPNVK
GVFEGNSVELVRAIKFLNAGVDFAGKPLKHTPKQIYPFCVTNSYAKNFSNIQKKLQKKLE
AGCTGIISQPVFDIDGARKLLEIFDDVRAGFSDERANAKLIFGIFPIITLKTAQFLHAHV
PGIQVPQFMIDRLFSASKIGVDEEKRVGVGMTKELMSGLAKINPRFHIMSANKFDFIDEL
LM
>A0A5D6VDE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter sp. KIGAM108|TrEMBL
MKVTEHLTRADGKTLFSFEVLPPKKGENIQNLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRKRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFKPEPDGHAYACDLIGQVADLNKGAYLDEEQDDVWATNFCIGTAGY
PEKHFEAPNYGADLRYLKHKVDRGAEYIVTQMFFDNEQFFNFEKRCRDAGITVPIIPGLK
PLTTKSQLTMLPRAFYLNIPEDLTDAVHLAPDNAAAREIGIEWCINQSRELMAHGVPVLH
YYSMGKSESIRRVAAALF
>R5KAA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:967|TrEMBL
MKLKEIYSTEKIIISFEVFPPKDSANKLLNEIGVLKKYNPAFLSLTCGAGGKENKSFDLL
NDIQNLNINVMPHFTCITSSKNSVEEGLQTIENLGIENILALRGDIPENPVLRHYDFNYA
NELVSYIKAKTNLSVGVAGYPEGHIESPDIKSDIINLKKKVEAGADVIFTQLFFDNDKFY
NYLQLLRDNGIEVPVAAGIMPVRSYKQIIKMTSLARVSIPQKLQADIEKFKDDTKSMTEL
GIDYASEQCSGLIKNNVNGLHFFTLNQSYSTAKILDNIL
>E0TJ56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zinderia insecticola (strain CARI)|TrEMBL
MIKNISFEFFSPKNKLGYKKLRINKIKLLKFSPIFISLTFKNYNKSQNYSLNNSLKIFRE
GDNLIPHLINFVKSKNLLLNLLKIYKFINIKNFIILRGDISFGFFNKNNINKNIFKFIKN
KNNIIKFASSYLNKHFNSNSFNEDIEYGMKKILNNTKFLITQYFYNINNYLSYIDKIYKF
NKEIEIIPGIMPIFNSKKIINFSKEYNNEIYKNNLLNLNNYKNNKKSYNLFNINNTINLC
NILINNGIKKLHFYTLNKFKIINKIIKNLK
>A0A2U8VYI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium radiodurans|TrEMBL
MPTASHHRASRDGYRPIRVSIEFFPPKTEEMEKILWTSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVDATKEEVDAVVQSYWDAGVRHIVALRGDPAEGVG
HAYRPHPGGYATTAELVAGIKRIGDFQVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFENEIYLRYRDKVRAAGIEIPILPGILPVQNFKAAANFARRAGASVPYWLAARF
EGLENDVETRRLVAAAVAAEQVIDLVDEGVQDFHFYSMNRSDLVYAICHLLGLRAQAPKV
APAKAA
>A0A4Z0H693|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces palmae|TrEMBL
MALGTASTRTDRARTVRELLASGERSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSLAELRNVIGQYADAGIRNMLAIR
GDPPGDPMGEWVRHPEGVRYAAELVQLIKESGDFCVGVAAFPEMHPRSTDWETDVGHFVN
KCRVGADFAITQMFFYPEDYLRLRDRVEAAGCDTPIIPEIMPVTNVRQIERFAKLSNAAF
PPDLAERILAVQDDPAAVRSVGIDYATDLCARLMAEEIPGLHFITLNHSTATLEIYENLG
LHQRSG
>A0A2T5LXQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus ochraceoroseus IBT 24754|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
ASRSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCVGVAAYPEGHPADSFQEVQDPEVDLPWL
VEKTQAGADFIMTQLTYDIDAYTRFETMLRNHESGAFKTIPIIPGLMPIHSHKILTRVTK
LSHVKIPPPILAKLEEVRYDDDAVKRIGVDIIAEIVDGVRKLVCPGLRGFHFYTLNLEKT
VSFIIERCNLIPDYPEDSEAVDVSEELSALTVDGSQASTLARRRRASSVGSIPHNRVIVD
RVTETSSKGSVTHETPAASAGMPALPPDRNTTLQISEGLGALGREATWDDFPNGRWGDAR
SPAFGEIDGYGPSLHVAPAVAHRIWGYPVTYDDISNLFRRHVSGDLYMVPWSEGGAEENS
SGLNAETETIRPELLQLIDNKGWWTLASQPAVNGVRSDDPIYGWGPPGEGFVFQKPFVEF
FCPTKDFQTVLKPVLKQHGHEKLAWFAANSKGEFETSLPAQSAEADPIEMNPANVNAVTW
GVFRGKEIITPTIIEEVSFRAWGDEAYRIWDEWRRIYPRNSPTERFLDKTRDDVWLVCVV
GQDFGAGTEIGSQEEQDEKKWMWNVLANC
>A0A074VTV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium melanogenum CBS 110374|TrEMBL
MASDRIVDKIAALPDDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVNVTWGAGG
STSTKSLALAEMTQRQLGLTTCLHLTCTNMSRKLIDETLEQAKALGIRNILALRGDPPRS
DEYRSNELENQEEDDSNREFTWAVDLVRYIRKEYGNYFCIGVAAYPEGHSDQSHPEHQHA
TYDLPYLVEKVEAGADFLMTQLFYDISLYQGYERMLRQHESGVFKSIPIIPGLMPIQSYQ
ILKRTTKLSHANLPCEVSNRLEPIKNDDEAVKRAGVDILSEMVETLKKSPSPGPKGFHFY
TLNLEKAVAHIVERCKLIGAANDFSAVEDDDTPVANGNGDKKAKARRRSSLANSAPQNRV
VVDKTTRSASHGSSSFEAFDDEAGVPGEDPPSRADALAISEGEGALGREATWDDFPNGRW
GDARSPAYGEIDGYGVSLHVSIPSALKLWGHPVDTKDITSIFERHVRGELSAIPWSEEGL
NPETATIKNELTGLIQKGWWTVASQPGVNGFRSDHEIFGWGPPGGFVFQKPFVEFFCSHE
DWTRLRAKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIEAVSFRA
WAEEAFGIWTEWRHVYPPRSASANLLRDIRDNYWLVNIIHHDFTETNGLWQMLLDA
>A0A066VAE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani AG-8 WAC10335|TrEMBL
MKLIEKLANYTSGVPYFTIEFFPPRTDQGYSNLLTRISGLASLKPIAASVTWGAGGSTRD
RSLDLAGFCQADNGLDTILHLTCTNMEKGTIDEALTTAMERGISTVLALRGDPPRGEEYW
IPADPRFRHAEDLVTYIKQHPKFGSHFCIGVAGYPDGHSEGGSEEEQLAHLKRKVDAGAE
FIITQLFYDVEKFKAWLRKVRNTGITVPVIPGVMPLQTYATFIRMTDLCKATVPQHIQAN
LDAIKHDDQLVKEYGVSLAVSMIRSILVDGDIKGVHFCTLNLEKSVRKILDELGWTHVFL
HHNQIITDANQSPRILPAPADALHPVNFTISPSEATQHAATSLAEHTRTGTLRTAAEAID
SGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPPHVAIAQWGRPTTEQELSDLFLAYLND
KTSTTPFSPEPLSDESATILPYLVSLTKRGLWTVASQPAVDGALSSDPVVGWGPRDGRVF
QKSFVEFFATEEDLEKVAKAIEDSGDGWVTFFAGNNDDGFLTNIPDSGSNAVTWGVFPGQ
EIAQPTNIDRDSFLAWKDDAFMIWHDFGL
>A0A3P4AYZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pigmentiphaga humi|TrEMBL
MSSSVPYGAAPADAAPVFSLEFFPPRDAAAQDRLVRSAQQLHGLRPHFASVTFGAGGSTR
DGTMLAVDILQKLGYQVAPHLSCIGSTKESLREILAAYRQAGIRRLVALRGDMPSGMGDM
GELRYARDLVDFVRRETGDWFHIEVAAYPEMHPQASGPDADLEHFVEKMRAGANSAITQY
FFNADAYFDFVDRATAKGVLAPIVPGIMPITNYTQLARFSDMCGAEIPRWIKLRLASYGD
DKASLRAFGHDVVAGLCQDLLDGGAPGLHFYTMNQAEATLAIWKEVGPPPTR
>A0A3L8RF84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rapamycinicus (strain ATCC 29253 / DSM 41530 / NRRL 5491 / AYB-994)|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSRADLRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWIQHPDGLNYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFID
KCRTGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATKLCARLMAEEIPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A2U3L3Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfotelmatobacter kueseliae|TrEMBL
MDTRENGQNSNFLRSALEKKEFVCTAELVLGRDHNVAEAETFVREASAQADGIKVISVTD
LPGGNPALPPEAFVSYVLEHNLTPIAHVTGKDGNRSSLEARLHALARLSVENILALTGDA
QKEGFAGKSKPVYDLDSVLILWLLRALHGGLEYNLGPKTVRTTPFDFFAGAVVNPFKVRE
PDLLMQFYKLQLKVVAGAQYIITQLGYNLRKLYELKQYMNREGIGHIPVLANVYVPTAKI
AQLMQAGEIAGCVVTDEFIKRLEQEKKPQRLERAALMVAAAKGLGFAGAHIGGFGLTHKD
FMTIVERAAVIGSDWRARMDELVFAFPGEFHLFRQGADGLSDGTSEYQVTQAKAHPSLVQ
RMSAMVHRHFIRDDSFGARLFGPRLQAGDHSVQNNSWRHGLWYRLLGPATLYRKATLGCV
SCGDCVQDHLNYAGCSMRWCYKELRNGPCGGSRVDGSCEARPDLPCIWNLIYLGSRAMGD
DPSKFGRVLVPPRDWCLDRTNALANRFAGLDNVCKRIDLRETKKEEREEETKPC
>A0A7W8X7T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium giardinii|TrEMBL
MAHIDENPLGRHLPLEPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VTNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTSPPQVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFKEYMKKVRDLGLDEKCFILVGV
GPMASARTANWIRNNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIKGVSGVH
VMAYRQEEYVAEIVHESGVLKGRTPWKREENPGDSMVAERLEHLKEGKPENQEEMAEIAA
HHPH
>A0A7D7A045|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium intestinale|TrEMBL
MKTKKKPLIFDGAMGTYYSMVSKNPSTKCELGNLYDRQTVLDIHKEYIDAGCGAIRTNTF
GANKEALESDFDVIKRVIKEGYEIAKEATKGTSVSVFADIGPIKELEGHELFKEYQEIVD
VFLDLGADNFIFETFSQEECLVDICKYIKSKNPKAFILVEFAVSPEGYTRLGNSGKKLID
KLSKINEIDALGFNCFSGPYHLLQYIKEFNIEDKTISIMPNSGYPTIINNRTFFDNSKEY
FASQMFEIAKLGVSILGGCCGTTPEYIKAMVLKLKELSLDDIVYDKISKPSEIRKSEVKN
KLIEKLDKGEKIIAVELDPPIDTEIDFFMSSAKKLKDQGVDAITIADCPIARARVDSSIL
ACKLKRELDITPIPHMTCRDRNINATKALLLGLNIEGVNNVLVVTGDPIPSAERDEVKGV
FSFNSSILANYITNLNETTFKSPFNVCGALNINARNFNAQMVQAKKKIENGITMFLTQPV
LTKEALENLKLARKELDVKILGGIIPVVSYRNACFMNNEISGINVSEEIIEMYKDISKEE
GTELAVKLSTQIAEEISEYVDGYYLITPFKRIDIISRIIENIKNK
>A0A843SJU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rugamonas rivuli|TrEMBL
MANHNFSIEFFPPKTAEGAEKLRITRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILA
AGEDAAPHLSCVGGTRESIREILTEFKSHNIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGEWFHIEVAAYPEVHPQAKSPQDDLLAFERKVKAGANAAITQYFYNADAYFQFVE
QTRKLGIDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQAAATTALWQRLVP
>A0A7D6VX03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium intestinale|TrEMBL
MFIKDIFKEKKVVFSFEIFPPKTTSSLDTIYKTIEDLKDLKPDFISVTYGAGGSTIDNKT
TLLSSLIKNKYGIESAAHLTCIGSSKKDIETILEDLKKNNIENILALRGDIPEDKTSSGE
FSYAYELISYIKEHGDFGISVACYPEGHLECRDLDLDIVRLKQKIENGAEHLVSQLFFNN
NVFYDFLERCSKKSIEVPIEAGIMPVINKKQIERITALCGAELPEKFIKIMNKYEHNPEA
LRDAGIAYAVEQIVDLLSSGVRGIHLYTMNNPLVARRITESVGSIITSLNKDIIV
>A0A2N2L5X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-10|TrEMBL
QLLDSGADILGINCRLGPGEIYRTMEQTFVPEGTILSVFPNAGRLGIIEGEFGYTSSPDY
FADRALHFRNQGVRIIGGCCGTTPDHIRAVAGVLRGLPPLPRINPENIQEPERISIITDV
TVRGKTDTILDKVKRRSTVLVEFDPPKDLDIEQYMIGAASLQDAGVDAITMADNSLAQTR
MSNLALGAIVKMRLGIDPLVHIACRDRNLIGQQSHLMGLHALGIHNILIVTGDPARIGDL
PGASSVFDVSSFDLIRMVKQLNGGISFSGQSLREHGRFVVGAAFNPHVNNLDNALKRLER
KIEAGADFILTQPVYDQATIEMLAANTRHLPVPIFIGIMPITSARNAEFLHNEVPGIRLS
DESLKRMAQYRVAGPEARRAGLDIARELVDVARVYFPGLYLMTPFAYYDMTAELTRYAKS
K
>A0A2H6EV13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Abin05|TrEMBL
MVADGAMGTALYGRGIPFSRSFEELNLSNPELVKDIHRGYASAGAELHETNTFGANRIRL
APHGLDRLVSEINRAGVKIAREAVGGEKWLLGSVGPLGKILKPVGKIDPEEAREIFREQI
AALVEGGVDLIILETFTDLREITQALLAAKDVDDVPVIAQMTFTEEGKSLMGDKPAEVVR
KLRELGAEIVGANCSVGPQGIYEIMEIMAQADAGYLSAMPNAGMPKMIEGRYMYLSSPEY
MAQYARRTVEIGVNIIGGCCGTTPEHIRQIRKMVWGKKPGERTKKGTSHFQFIESTEITA
PPEEEKSVRESNFAVNLGKKFLVSVEIDPPRGVDPEKFIQGALYLKGKGVDAINVADSPL
ARARMSPLVLSHLISEETGIETIMHLSCRDRNILGLQAELMGAQALGIRNILAITGDPPK
LGDHPTATGVFDIDSVGLVTLIRNLNNGVDLMGRPIKSRTGFSIGVGVNPTAIDLDYEMN
KFARKVEAGAQFAFTQPLFDLKILEDFLKRAEKFEIPIFVGILPLRNFKHAEFMHNEIPE
MFVPEHIRKMMFDAGENGPEVGVQIAQKFLLNAKDRVDGVYLMPPFNKFEMAGAVLKVLE
>A0A2G1UN76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter profundi|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQAVRDQLAAVNPDFFSVTFGAGGSTRDRTIETV
LSLHKQGISTAPHLSCVGGTRQEIAELLDLYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARSAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEQMNITIPVVPGIMPIVNFSSLVRFSEMCGAEVPRWIRKQLEAYGDDSESILK
FGEEVVTNMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISEREKIAF
>A0A7Z7BIZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium fabrum|TrEMBL
MGWSSFWDNSGADGDVVRSGNILAGWSIEVMPRTAAKIDDFRNILPDGTRVYIAHIDGTP
IADMVSTAKRLHDEGFPVMPHLPARGISGKNELEDWLKRYQGEAGVTQALLLGGGQKQPA
GSFSSSIDMIETGLFDKMGFTHLHLAGHPEGNRDIDSDGSSRGVDQALLWKQDFASRTDA
RLALTTQFAFDAKAVIEWAKRIGNMGVTIPIHVGIAGPTKLQTLIKFAIACGVGPSLKVL
QKRALDLSRLFVPYEPTDFIAELIDHKAANPDSLIEHVHIFPLGGIKPSAEWMKKHASTG
TLANVA
>A0A564WBX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Defluviicoccus seviourii|TrEMBL
MTDRLRSTTLLSVAAPLPGDVKVSFEFFPPKTAEMEEKLWACITRLATLEPAYVSVTYGA
GGTTRERTHATVVRLRTETALEPAAHLTCVGATRAEIDAIAERYWAAGVRHIVALRGDPP
EGATHYQPHPGGYAYACDLVAGLKRVADFEISVAAYPEMHPEAPSAQFDIDNLKRKIDAG
ATRAITQFFFDVDIYFRFLDRCQAAGITVPIIPGILPVTNFGQVVRFAKQCGAAVPGWMG
ELFAGLDSDPETRRLIAASVAIEQCRALHAGGVKQFHFYTLNRADLAFAICHVLGVRPKA
EAQAQPTPQARVGDSR
>A0A2E9G7X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobius sp|TrEMBL
MKVTEWIEKSDKTLFSFEILPPLKGQNINNFFEAIDPLIEFKPAFIDVTYHREEYVYKSR
GNGLLEKITTKKRPGTVGICAALMNRYHVDTVPHLICGGFNKKDTENALFDLNFLNIQNV
LLLRGDSIKSEGRFVPDPNGHDYADGLVEQVVGMNEGKYLGEEIINPNTTDFCIGVAGYP
EKHFEAPNLEVDLKYLKKKIDLGAHYIVTQMFFDNQKYFDFVKKCREIGINVPIIPGLKP
LTNKKQLTVLPSIFHIDIPQDLFSAVEKCKTNQEVRQVGIEWCTQQSKELVKFGVPCLHY
YSMGKSGSVKQIASEIF
>A0A2D0N5F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavilitoribacter nigricans DSM 23189 = NBRC 102662|TrEMBL
MKVTEYFEKANGQTLISFEVLPPLKGGSMQAIFNTLDPLMEFKPPFIDVTYHREEFIYKK
RSSGYYEKTAIRKRPGTVGICAAIMHRYGVDAVPHLICGGFTLEDTENALIDLNFLNIKN
VLALRGDARKFEGRFIPEEGGHSYAIDLIRQIKEINGGKYLDTNIENGEPTDFCIGIAGY
PEKHFEAPNMGTDLEFTKAKIDAGANYIVTQMFFDNKKYFEYVKACRDIGIDVPIVPGLK
PITKLYQLNSLPRLFHIDLPTDLVKALEQAKNAEARRQVGIEWSIQQSKELKEAGVPCLH
YYTMGDSDTIRQIVESVY
>A0A367U749|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira xianhensis MCCC 1A02616|TrEMBL
MTVKNDIAPQGTSRSDLRVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGST
RDRTHSSVTRIQGETGIPAAAHLTCVGHTKEEIEGIARNYWDEGIRSIVALRGDLPDAGD
KYVPTPGGYPYAVDLVEGLKRIADFDISVSAYPETHPDAPNADFEIEYLKHKIDAGANRA
ITQFFFDNEVFLRFRDKCAAAGITAPIVPGILPVTNFGSLLKFADMCGASVPKRLHWRFE
DLDEDPDTRRMVAFHEAISQVEGLMAEGVTDFHFYTLNRAELTYAICHALGIRGVAQAAA
>A0A5J4SLI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|termite gut metagenome|TrEMBL
MKIIDLISGSEHTAFSFEILPPLKGTSIGGLYNTIDMLREFTPKYINITTHRSEYVYTDS
GNGAYQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLIDLQFLGITDL
LILRGDKAKHESLFIPEENGCLHAIELQEQINNFNKGVFIDGSKAKEAIIPFSYGVACYP
EKHEESPNMDNDIYWLKKKVEAGAEYAVTQLFYDNNKYFSFVEKARKAGISIPVIPGIKP
FQKLSQLSMIPKTFKVDIPEDLSREILTCKNDDEVRQVGIEWCTAQCKELIARKAPSIHF
YSTSAADSIREVARRIY
>A0A4Z0LRG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Poona|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGPLPAVAEGDSSVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRFVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFLFYTLNRAEMSYAICHTLGVRPGL
>T1XH55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax paradoxus B4|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPEFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFLYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFATKVKAGADSAITQYFFSPEAYFRFVDD
VRKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLRDGGAPALHFYTMNQSAATLAVLERLG
>K1WXP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marssonina brunnea f. sp. multigermtubi (strain MB_m1)|TrEMBL
MEKITAKIAALPPGSSYFSLEFFPPKTTMGSSNLRARLDRMSRALRPLFITVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YREVDEKGQSAGAAMEEEFEWAADLVRYIRKQYGDYFCIGVAAYPEGHADESDPNGQSLE
HDMQYLVGKVAAGADFIMTQLFFDVQAYDAFERKLREHESELFKTIPIIPGMMPIQSYQM
IMRTTKLSHARMPPDVMGRLDEVKGDDEMVKKVGVDIVSEIVTHIRRQPAPGSRGFHFYT
LNLEKAVSFILERTNLIPPIPLDSESAILDVSSSLGSLQVNGSSHKRASRRLSSIGSDPH
NRVIVSGQKATNPDREATAEEAGVPAEPINTRANTLAISEGEGSLGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHMSVNQAIKLWGFPTSAADITSLFIRHIEGSLSAIPWSEEGLN
EETNTIGSQLLKLNQKGWWSVASQPAVNGVKSSDSIFGWGPKNGFVFQKAFVELFLPSSD
WATLHAKLASAATAPTVSWYAANATGEFLSSFPNSDADNRREGGAGGSTNAVTWGAFPGK
EIITPTIIEEVSFRAWAEEAFSIWAEWGRVYPMRSATKACIDAVAGDVWLVNVIHHEYVE
KEGLWELLLST
>E8JVL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus cristatus ATCC 51100|TrEMBL
MVNRQTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLAE
FISNDLEIPTIAHLPAVYLTKEMVSNILQVLDRVGVNQILALRGDIFPDVAPKDDFRYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRT
AGLAYAVDQIVDLVTHDVAGIHLYTMNNAATAYHIYKATHALFNHTPSVQSF
>A0A2G6CGU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium|TrEMBL
MTTPRISFEFFPPQNIEATFRLADTVRDLAPLQPSFVSVTYGAGGTTRELTHDAVATIHK
RFGLNVAAHLTCVDATRAETLEIAEKYAQVGVTEIVALRGDPPKGTARFTPHPEGFKSSV
ELVEALAQTGKFKLRVGAYPDPHPEAADADADVAFLKRKIDAGAHSAITQFFFEADTFFR
FRDKCAAAGINAPILPGILPIENWKGVRNFAARCGTSVPGWLDDAFAKAAEDGSQDALAV
SLATELCSDLIAGGVEDLHFYTLNKPGLTREVAQALGVTA
>R5LII1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:115|TrEMBL
MKIPELFKNGHTVFSFEVFPPKKDADVSVIYDTLDQLGDLHPDFISVTYGAGGSAAGATT
TELVRHIKENLGTESIAHLTCVNSTHADIDEKIKEFEANGIENVLALRGDINPNFPPKNE
FLHASDLIEYMKPRSNLSFSGGCYPEVHPEASSMVEDILHLKKKVDAGASHLISQLFFDN
SSFIEFLEKARIAGIDVPIEAGIMPCVNAKSVQRMVSMCGASLPVKFTKMINRYGDNPEA
MRDAGIAYAVDQIIDLVAHGVDGIHLYTMNNPYVARKITESIEKVIRCDK
>A0A2G6IDV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium|TrEMBL
MSRAALSFEFFPPKSLEASFRLWNCITTLEHLAPDFVSVTYGAGGTTRELTHEAVGTIHK
TTGLNVAAHLTCVDATRDETLAIAEGYAEAGVTRIVALRGDPPKGQGRFAPHPQGFSGAP
ELVGALARSGRFDIAVGAYPERHPDAGCAQDDIDQLKRKIDAGASTAITQFFFEPETFFR
FRDACVSAGIDATIIPGILPVENWAGVQKFAAMCGTAIPQVVRDAFENATAQGSTDLLAT
ALATELCDDLMEGGVEHLHFYTLNKPELTRDVCHALGLAPDPALHQVA
>A0A8H5KNI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium pseudocircinatum|TrEMBL
MAANRTLQAEAEWDVVNCFSQTEPIKSTVSKLIADVTARSIVLGLSPIKRGAAEYNGNQF
NARSRYLHSIKWSSSPADFTMHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDR
MYNLGPKFIDITWGAGGRIAELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAY
KAGCTNILALRGDPPRAQDKWTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDN
KNEDELLDHLKEKVDMGASFIVTQMFYDAENFIRWVKRVRERGITIPILPGIMPIATYAS
FLRRANHMQAKIPQEWLDALEPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNL
AQATRMLLEELQWAPCAERPLQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWD
EFPNGRWGDSRSPAFGELDAYGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESL
PWSEAPLTTEADEIREELIELNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYL
ELLVHPDVFDKMITRIENHPDLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTI
VESISFLAWKDEAFRLGVDWAHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFEL
LKGLEVKDLTTPATPLTESVGNGAVDTEPIANGTAATAVAN
>K6XT07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia namibiensis NBRC 108229|TrEMBL
MRIALYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFMPPRDAEGEARLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSIAELRALVGAYADQGIA
NILALRGDPPGDPLGEWIAHPEGVEYAEELVHLIDTLGDFHVGVASFPEGHHRAPDLEHD
TRNLVNKLRAGAEYSITQMFFDVEDYLRLRDRVQAADPEQGAKPIIPGIMPVTSLASIKR
MAELSGSVIPPTVIERFTKAAGDGPEEDRASVRAVGIDFATETAERLIAEGAPCLHFCSL
NFAKATSEVLGRLGVDVDAALHVPA
>A0A354K4U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKAAALFGGKPVLSFEVFPPKPNVPIDSIYQTLSALKDLHPDFISVTYGAGGSVPGASTA
EICETIQNTHGIPSIAHLPCINETRESVLEKLEQFRARGIENILALRGDRNPDVEPKDDF
HYASELIAFIREQGDFDIAAACYPEGHPESPDLDTDISHLKEKVDAGASHLISQLFYHNP
DFYAFREKIAAAGISVPVEAGIMPVTSKKSIERMVSLCGASIPNRLAKLMARYSDDPASL
KAAGLEYAIMQIDDLLANGADGIHIYTMNNPDVARYIMEQIAEAAGR
>A0A5P2AX00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces venezuelae|TrEMBL
MSATCVNPTFSFEFFPPKTDKGERTLWDAIRRVEALSPDFVSVTYGAGGSSRDRTIEVTK
RIAAETTLRPVAHLTAVGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRGAWTPHPQG
FTYAYELVELVRSLGDFRIGVAAFPEGHPRSAGPADDLAHFVAKCRAGADYAITQMFFDP
EDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAKDDPAS
AYRIGVEHATAMGLRLLDEGAPGLHYITLNKSTAALEIHRTVLSARRVAAHV
>A0A3D4NRR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVDIPIVPGIMPMHNFKQARNFVTRAGTTVPDWLAEKFEGLDDDAETRKLVA
ATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPQGAQKAA
>A0A2M7CDR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG03_land_8_20_14_0_80_45_14|TrEMBL
MKAGSNLEKVLEKRLFAVTGELGPPKGNDVSVIKRKAELLKGYVDAVNVTDNQTAIVRMS
SIATSSLLIQLGLEPVMQMTTRDRNRIAIQSDIFGATALGIKNMLCLTGDHHTFGNQVDA
KNVHDLDSIQLIDCVRTMRDQGRLLGGEEKIEGEINIFIGAAANPFADPFEFRVIRLGKK
VAAGVNFIQTQCIYDMNRFKEWMRMVRDRGLHEKCHILGGVTPLKSGGMARYMAKNVSGI
IIPDEIIDRVVKAKKPAEEGIKICVEQIQELREIEGVHGVHIMAIEWEQMVSKITEMAGL
LPRPKIE
>A0A267EWS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
MPENSSSVAKMPAKEKLQQEEQERPQPPTSRQYRPLATRIRRRIEKGRRWFSCEFFPPRT
PAAAVNLVSKFDSFARGRPLFCDVTWHPAGNPAGDSPTSSTSVASAMLNYCGIDTVLHLT
CVGQTEARLVRVLDRAKSLGLKNILALRGDLPEDADGNPGGASAAASGGPAFASDLVRLI
RRRYGSFFCIGVAGYPAGHPEAASYAEDLRRLKEKVDAGGEFIITQLFFDSADFIRFVSD
CRRVGIDCPIIPGVLPVQGYQSLRHIVKLSKLTVPDSMLRVIEPIRDNDEAIRNYGIAQC
TQMCQELLQSGQVHGIHFYTLNRDAATIRILKNIGLWREDLPRPLPWQPSANYERCAEAV
RPVFWSRRPTSYVHRTRHWDDYPHGRWGSECAEIGELRDYYLFYLTVRASKQERLRMWGS
EPTSEPDIWRVFASHLSGKPVSPDGVRVTRLPWGDEEPLPSSSESNEAAEARQRLAGLSE
RGLLATNHLLRVNGASSDHPVHGWGGSGGFVYQRAYLEFFLPGRRLPALQSALSSHGGGR
VSFHIADRSGNVNLANFSEPIALTWGVFPASEVAQPTVCDGAAFLAWRDEAFALWTEEWG
RLYEEGSPSRRLIESVAETYLLVALVDNDFTEDSVLWDLTDQVARAADGSDEVELA
>A0A3D0K3A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
LGVQTPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQAFGEQVITEM
CQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A3D0K371|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLS
>A0A1V5TZS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium ADurb.Bin248|TrEMBL
MELTNLIGGTAPSLSFEVFPPKNSANYESIRAAVEEVASLSPSFISVTYGAGGGTSDYTV
SLAADVQDRFRLPVLAHLSCVNATRAGVRAQLDAMRRRGIANVLALRGDMPPGSAPQENW
DYRYASELVAEIREYGGFCVGGACYPEGHTESPSQKEDILHLKEKVDAGCAFLTTQMFFE
NNVYYNFLFKARDAGIRVPIVAGVMPVTNASQIRRIVALSGTALPQRFRYILDRFGANPA
TMRQAGIAYATEQIVDLFANGVQAVHVYSMNNAFVARKIKENLSEILK
>D4YLL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium mcbrellneri ATCC 49030|TrEMBL
MTTLSASAPLDTHTSGPVTDTSGRREDGTLAETWETGTLAAGTSEREPGHQPESRLALSF
EVMPPRSAQQQEQSGELLDLLASYDPDYVAVTSAVRTGWSAGTAAFISQLSATTRLRPLA
HLACTAAPRDELVTWIERYIDSGVRGFLAIRGDLAPGATAPPAGHLAHADALVTLLRSVE
RNQVARLCAGRFAIGVAAYPSGHPESKRPEEDIDVLAAKQRNGADFAITQLFFNPAQITT
MSRRADLAGVTLPIIPGIMPITGSARLKRMCQLSGLTPPAYIAQALAAAGSPAEEYEIGL
SLTADFVEALVAVGVPGLHFYTFNDPTTITELLSRLSPQTRARLTTTRKDTP
>A0A165SSP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. HI00D65|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASSEELIQIADDYWANGIESIVALRGD
IPPGGGTPEIYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMVKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRP
>A0A853B6I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis endophytica|TrEMBL
MTSVIERLRGETTAFSIEFFPPRDTADEAVLWRSVRELEPLDPAYMSITYGAGGSSRDGT
IRNIARVATETTLTPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGDWV
PHPQGLRYAEELVSLVRSLGDFCVGVSAFPYGHPRSPDLDSDTKYLVRKFNAGADFGIAQ
LFFQPEDFLRLRDRVAAAGCDALVIPGVMPLTTPRTLHTTIRLSGAEAPQGLLDRLEPLA
GDPKAFRAEGLDVVTELCERLIAEGVPDLHFYTFNRSKATREVVRRLGLVPARA
>A0A7X2FXS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HT1-32|TrEMBL
MHNLAIDPHLVAKQAIIRFLDGCSVEVTPTQATKVGDFTTHLSPGQRVMVTFLPGSDWRA
TVNTARMLREQGFEPVPHIAARSIPDTAMLEDFLKALREEAGIREVLAIGGGVDRPVGKF
DCTLQMLQTGLFQKYGIFRIGVAGHPEGSPDIPEAIVRQAMIDKNRFAGQHGLQMDIATQ
FCFEVDPIVKWERQLRADGNRLPIYVGIAGLATLKTLMAHATACGVGNSIRVLMKQAGNI
TKLMSVREPDAVVGGLAMEMARDPDSLLRGAHFFPLGGLRRTAAWMQAVSNGDFEASADG
TTISLHKPID
>A0A8G1GYX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deefgea sp. D13|TrEMBL
MTNPLRPISFEFFPPKTDEGAAKLATTRRQLAQFNPEFFSVTFGAGGTTQEGTLRAVVDI
QAAGHAAAPHLSCIGSTKDNIREVVQQYKNHGIKHIVALRGDIPSGMGEFGEFRYANELV
SFLRSEFGDWFHIEVAAYPEFHPQSLNAEADLRNFINKVNAGADSAITQYFFNADAYFRF
VDEVQARGVNIPIVPGIMPIQNYSQLQRFSDMCGAEIPRWLRLRLQAYADDTASIRAFGL
DFVTELSDRLLAGGAPGLHFYTLNAAGAVSTVCQRLGY
>A0A8J7LRL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snuella sedimenti|TrEMBL
MKVTEHIKRANGKTLFSFEVVPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVD
KGNGLFDKRITRMRPGTVGICASIMHKYNVDAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VVALRGDSRKDEPYFVPTKGGNAYASDLVEQIANLNKGKYLHDTVEVEHNYDFCVGVAGY
PEKHMEAPSLTTDLKRLKAKVDAGADYVVTQMFFDNNKYFEFVDKVRAIGIDVPIIPGIK
PLAIKRHLQVLPQVFKIDLPQDLIDAVEACKDNKAVRQVGIEFAIQQSKELKAAGVPFLH
YYSMGKSDNIKAIASELF
>A0A800KTX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium|TrEMBL
MKISFEIVPRTPQAFDDQYRFALSLGESISMINVPDIQRFDIRSWDTAKKINRNVHQFVP
HFRATDFSLESGKLFEIIEENELDHVLLVSGDPPEGMRKVHNTSVLDLISAVHKRFPKIT
IHAGFDPHRSGLQDECDYVFRKVDAGASSFFSQPFYDTRLIEIYAEHLQGIDTFIGLSPI
TTTASKNYWEVKNKVKFPNAFKAEYDWNINFSNQVIAMARDMDFNIYFMPIRIDLESFFG
KLNLR
>A0A060RL66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gallolyticus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADIIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVKIAREAAGDDAFVLGTVGALRGLKQCDLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEAELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKETNFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDELAYLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALEHFNGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A8C5E0Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gouania willdenowi|TrEMBL
MLQALHTANIKSSSSKSDSSGASGGDSSKESSRCSTPVLDADRSDRLRDKMRKRIESGDH
WFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVN
YCGLESILHLTCCNQSKEKITAYLNKAKHLGLKNIMALRGDPVGSEWEDEEGGFNYAIDL
VKHIRSEFDDYFDICVAGYPTGHPEAETYEADILHLKEKVDAGADFVISQLFFRADTFLK
FVNDCRAIGIKCPIVPGVFPVQGYQSLRQLAKLSKLEVPEEITRVIEPIKDNDAAIRNFG
IHQAVEMCRLLLDSGIVPGLHFYTLNREVATMEVLRQLGLWNEDPRRPLPWAMSAHPKRK
VEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALL
QMWGEELMNEQSVYEIFTCYITAQSNPCGHKVLCLPWNDEPLAPETNLLKDELEKVNRRG
VLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKILKKYEPRVNY
HIVNVNGRNWTNANDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKL
YEDESPSRMIVKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLSEAQELLSDGAISE
>A0A4S8P449|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium ipomoeae|TrEMBL
MTDTNPTIGNDQTMKVSFEFFPPKSPDMEGQLWETVKALQAVSPDFVSVTYGAGGTTREP
TLATVRRLIAETPLATAAHLTCVGATRQDVQAVVEEFRAAGVRHFVALRGDPQGGVGSRY
EPHPGGFENAAALVRGLRDMGDFEISVSAYPEKHPESADDAADIDMLKRKVDAGATRALT
QFFFDNDVFEAYLDRVRAAGISIPIVPGIMPIQNLTQLKRFAGMCGASVPDAFDRRFAAV
EGDAQGRAAVAADIAAEQIADLKRRGLDEFHIYTMNRAPLTLATLARLGVVGAKDRTEAA
A
>R5I1B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia inulinivorans CAG:15|TrEMBL
MRLTELLNKDEVTISCELFPPKQGAQLENYKNIVKDMAALKPAYMSVTYGATGGTSDYTV
KLAEEVRNNNIPALAHLTCASSTKEKVASVIEELKAANIENILALRGDIPANADFPLPDQ
YKHASELIADIKAQGDFCIGGACYPEGHPEAATIFEDLDHLKEKVDAGCEFLTTQMFFDN
NILYNFMYKALKKGIDVPIVAGIMPVTNASQIKRITSLSGNMVPPRFLAIVDRFGDNPAA
MRQAGIAYATEQIIDLIANGVNHVHIYTMNKPDVAGEILDNLSNIYVR
>A0A5C8AWU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEEQVSDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWSIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A1Z8LTB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium TMED8|TrEMBL
MPLTASNLADESIDESVRSFVNGFTAETTPFSAAKIDDFREVLRPGTTVFVTFLPGSDYT
DTLEVTKRLQDEGMRPVPHIAARSVPNKAFLEENLKILAEQSGIDEVLIIGGAVDQPVGD
FSDSMQIMETGLLDKYGIKKVGIAGHPEGSPDITQEAIRDALAWKNEFAERSGAELYIVT
QFCFEAEPIIAWDKAIQSEGNRLPIRIGLPGLATIKTLLNFAKACGVGQSMNFLKRQGKN
VAKLMTVSTPDKQMIDLARYKLEDPKCGITGVHMYPLGGVKKTAKWSYAVCDGHFDVTPK
GDGFKVNIDL
>A0A5C8GSJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lavendulae|TrEMBL
MALGTASTRTDRARTVRDMLAGGKTTYSFEFSAPKTPKGERNLWTALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNILAVR
GDPPGDPMGAWVAHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADRDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVEAGCDTPVIPEILPVTSVRMLERLPKLSNARF
PDVLKERILAAKDDPAAVRSIGIDFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHHPPRA
>A0A4Y4C3K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium variabile|TrEMBL
MSPAPSPESLSTTPPPPSLQVAVSDTLKRGTPGRVPFSVEFMPPRDDAAEARLWSAAEAF
HDLGASFVSVTYGAGGSSRARTERVAGRLAVKPLTTLLHMTLVGHTEEELRGILREFASL
GLTNLLALRGDPPGDPTGEWQGIAGGLSHAVHLIELVRSMPECEDFDMGIASFPEGHYRA
ESIEADTRYTVEKLRAGANYSITQMFFNVDHYLRLRDRLAACDPVHGAKPVIPGLMPITS
LRSVRRQVELAGCELPRDMEELFTKVADGDERKNAAAIREVGIEVTTKMAERLIAEGAPD
LHFMTMNNVRATQEVLHNLGMAPAYGPKFGQDMVR
>A0A1V5F3Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.BinA395|TrEMBL
MSIVDKIKSSSSTAFSFELLPPLKGDGIASVFKTIDLLREFDPKYINITTHRSEVIFKQN
DQGLFEQSDVRRRPGTVAIAAAIKSKYKIPVVPHVICSGFTKEEIEYELIDLQFLGITDL
LLLRGDKAKHEKDFVPTGHMHATDLQQQVNNFNKGIFLDGSRMKALPAEPFSYGMAAYPE
RHEESPNTESDLYYTKMKVDGGAEYLVTQMFFDNQKYYDFVDKCRNMGITVPIIPGIKPI
TLMNQLTVLPKIFHTEIPEEFASELRKCKTDAEATEVGVEWCTKQASDLKAHGVPSIHFY
SLMAAQSVKRVAKAVF
>A0A1F0BEG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC074B11|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQDLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQPQGS
>A0A0E3PU76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina mazei WWM610|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRFSASLEDASQLKGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDYPTCGDHPGSKP
VYDVDSVQLIELVRKLDTGVDFAGNKLDGGTSFCAGAVSGIDPEKTMQLIKLQKKVKCGA
DFIQTQAVYDIGMFEEFMDAVNYLEVPVIAGLIPLKSLGMAEFMNKNISGIHVPEEIMLR
MKDASSPMEEGLLIASETIKELTKLSRGIHVMPIGSHRNTARLLSLAGISQK
>G7VDX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrobaculum ferrireducens|TrEMBL
MEIIAEITPSLNKAKLVGRLEAVRRYVEKVDIPEAPGGKPTAHSLAVGVLAKQLGLEPIV
HIRLVDLNKTAFKSLLGGAHILDIRYVVVLQGDPPAEGKPVGEITTEEAVAAAKSMGFKT
GALLSLRRDYAKRLEIGADFYLALHFTEPKQLQGLPPVVYPYILVKTGRNASILEKLGQT
AVTPGEALGLIHQLQEAAPGVVLSAPGDHHALLQLLEKLRS
>A0A2H1EGF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosotalea sinensis|TrEMBL
MTIIYEINPPKVIEDTILSHDQLSGSVERLKQRALEIGKVCDGIHLTDSVLGVPRVSPIT
AGFFVRNSNNKIGVTASIRVRDRNITSITQTICDAILLNLNGVLVLKGDAPPQGPQDSGL
VPSDIVRQFNEQGFSKRIDMYLSVSSQPNFEKMHKKIEAQPKGFITQVISSIDQVTRIVD
HLKPQGFRVIPCILVSSEKNKKSAQMLNLDWSQYSKDIVSFVKQVEKTAGSVLLSSPNDF
AVALNLLNQL
>A0A8J5L3L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MVEGNVEQKTVNVFERPPSSPDIIAMIVDLKISMITECNMATNEKPVDWWFETGHVLGVL
LASSPLLEQAWTRCLRANAGSASFVIDKSDDAVFITFSRAQATASPSGLGRGFFEHVSLY
SSTHKLFALLGRGEEDSGGKPQPVLLQIDHALNTIKANGIQNVLALKGDPPHGQDKFVQV
AGGFACALDLVQHIRAKYGDYFGITVAGYPKAHPDMIQGDEGATLEAYNSDLAYLKRKVG
NL
>N9R002|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter colistiniresistens|TrEMBL
MLSLFAQHLGQDRFCILVEYLCSTQSILPVPQSIAGFPAMMTLADRVQTDEDPAPIEFAQ
YYPETIEKVLHFSGKGRDMTEFETFLDQAEQAGQQNLLLLTGDKLKKHSSGQRLATDRTR
YLESVNAVIAAKKRKTFHIGVAFNPFKYTEAERDAQYFKLHKKIRAGADFLITQLGFDLE
QTKHAQALLALDYPDFPLIACVMPLTLRRAQFMLRHQVAGIVISEHVLKVLEQEDRGDSA
QAEKNVYARCALQILICKHLGYKGVHLSSCHKPQEQTQLEQALQQYQHLSLTECEQLWYQ
LWQTTTHRVFQPRVEIFRKKVTSTQIFKYKNMQLLHGVFFSSKAALQVGRFVFKAAFWDR
PNASHLLLKVEHFSKHHAVGCDSCGQCRLSETLYICPEICPKGLANGPCGGTTLDRCEFG
DRECIHSVKARLAKAVGQTELLKTELIPAVSIETRATSSWKNWFKSIES
>A0A2Y9KFK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enhydra lutris kenyoni|TrEMBL
MMIASTAVNYCGLETILHMTCCCQSQGQITGYLHKAKRLGLKNILALRGDPVGDQWEEEE
GGFSYAADLVRHIRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQL
FFEADTFFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSRLEVPQQIKDVIEPIKD
NDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPW
AISAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLK
SKSPREELLKMWGEELTSEESVFEVFAHYLSGEPNQHGYKVTCLPWNDEPLAAETSLMKE
ELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVGALLQVL
KKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFA
LWVEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPEPE
QDTQAL
>A0A8J5GM51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MTKTSQRSPARTLQPASKTPSFCTSYLLIPNRSSKSPRGPRSEEQPTIATARREISTGYK
IGIASSAQLGDRQRGNSNRREKESKSWSSGHVLGVLLASSPLLEQAWTRCLRANAGSASF
VIDKSDDAVFIAFSRAQAAASPSGLGRGFFEPVSLYSSTHKLFALLGRGEEDSGGKPQPV
LLQAPYEEEAQCAALCKSDKVCMETIMHLTCMNMPVEKIDHALNTIKANGIQNVLALKGD
PPHGQDKFVQVAGGFACTLDLVQHIRAKYGDYFGITIAGYPKAHPNMIQGDEGATLEAYN
SDLAYLKRKTLSVVLKFWKSFSHVKILELCEIFILWSANS
>I2C3E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus amyloliquefaciens (strain Y2)|TrEMBL
MGLLQDLEERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIADLGADITGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTDKEVKIRREEEVI
SVRNERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A2G6QJ27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus fungorum|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVNEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHITLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1I5FWM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus obscurus|TrEMBL
MTASVRELLTSSRPTWSFEFFPAKTPEGEAQLWTALRRLESLRPSFVSVTYGAGGSTREG
TVAVTERIAAETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQAD
WVAHPQGLRYASELVELIRSMGDFSVGVAAFPERHPRSPDFDSDVEMFVRKCRAGADFAI
TQMFFRVEDYLRLRDRVAARGCDVPVIAGVMPVTNARQITRIVQLSGQAFPEDLAARFAE
LDGDSPEDKAAVRAYGVEVATAMCRRLLDEGVPGIHFITMNRSTATREVYANLTDAATGM
SVPSTLAATP
>A0A0A1H923|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium GJ-E10|TrEMBL
MHDNCIFSVEFSPPRTAEGVEKLRATRAELARLGPAYYSVTFGAGGSTREGTLSTALEIH
RAGLRAVPHLSCIASSRVELRDLLETYRAAGIRRIVALRGDLPSGMAASNGDFRYAADLV
AFVRAEFGDAFHIEVAAYPEMHPQARSPAEDLRHFVAKVQAGADSAITQYFYNGDAYLRF
VDEAARAGCTVPIVPGVMPITNFSQLARFSDSCGAEIPRWIRRRLESFGDDRDSIRAFGL
DVVTTLCERLLAHGAPGLHFYTMNAAHATTELWRRLRLPVPTSDAFPSAAAGA
>A0A3A1WTR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacteriaceae bacterium WP012|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VYYIRSKRPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNADCLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A016QPZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus phoenicis|TrEMBL
MTRVSIELVPRSRSSLKAELEVVAQHLPGICTVNVPDLTRFSTRSWVGCGFARPRYRAIP
HVRAVDLNPVEVLPMAEALEAAGIDEVLIVTGDAPADMSARVYDVDAVRAIRRFRRELPH
VRVYAGLDPYRQSFARERDYLERKLDAGACGFFTQPFFDLRLMNAFADLIPESAEVWWGA
TTVTNDATLNYWRARNHAVFPRSFTPTLEWNREFAAQALAFARERGQHMYFMPVKADVRA
YLEGIV
>A0A174IVC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium disporicum|TrEMBL
MKIDEIFAKKDLVFSFEIFPPKTTSSVDTIYKTLEELKDLKPDFISVTYGAGGSLVNNRT
TELSSLVKEKYGVEAVAHLTCINSTKEEIDYILNDLKSHGIENILALRGDIPEGGVLKGD
FKYAYELISHIKKRGDFNIAAACYPEGHVKGKNLKEDLIHLKLKEESGATHFISQLFFDN
NYFYNFLEEKDKLNIKSSIEAGIMPVTNKAQIERLTSLCGVNLPEKFIKIVNKYEYDRVA
LRDAGIAYAVEQIVDLVSSGVDGIHLYTMNNPYVARKITESISSIINSINKQKAI
>A0A2P7TWY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria iguanae|TrEMBL
MSYAKEINALNNSLCDLKGDINVSFEFFPPKNEQMETMLWDSIHRLKKLHPKFVSVTYGA
NSGERDRTHGIVKNIKQQTGLEAAPHLTGIDASPEELKQIAQDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKVLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVTVGIDAEIVPGILPVTNFKQLGRMAQVTNVKIPNWLARMYDGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHTLGVRPIAQAA
>T0KSW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas hongkongensis|TrEMBL
MFAKLIDKLKNDTYITLETTPPNSPQFAPIIDKIEALGLHNLVDAFSTTDNPLAKLKYNS
LFAAKMLQDRFNKPVLATMTMRDRNKIALQSDLLGANEVDVRAILALTGDPANISDQPHS
KGVFEADSTLLLDIISAFNSGMSYAGKSLGHKPREIYPFAVVNSYAKNPKTLQKKMQKKI
KHGALGIITQPVYDIENAKMLLDLIEAANRDSLPKYKEAELVLGIFPITKLRTAQFLSAH
VPGINVPDRWIELLRVANKRGEEEEYKVGFELSKTLFESIKELHPKIHLMSANQFNLAKE
ILK
>A0A5N7B693|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus bertholletiae|TrEMBL
MHIKEKLSQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAADGGLRYAKDLVKYIRNKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDIFISWVNKCRAKGINVPIIPGIMPIQTYSAFIRRANWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLMPSEETP
IQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIRDLSHLFVRYLEGKLGRLPWSDTPISSEAKTIKPNLIE
LNNRGILTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHVATSPSRKLIQSLVDNWYLVNIVNNDFHNTYSLFELFKDLNVRDFDVEVTADNDDSK
PQENETATATAN
>A0A5N7SDS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYDPQYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQG
>A0A453M7X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aegilops tauschii subsp. strangulata|TrEMBL
MLQIIIVISVFQMSEAHPEVILGEEGATEEAYSKDLAYLKRKVDAGADVIVTQLFYDTDI
FLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTKIPAEITAALDPIKDNEEAVK
AYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNLGLIEESKLSRTLPWRPPTNV
FRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWGDSRNPSYGALNDHQFTRPRGRGKKL
QEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPETTIIDDQLVKINSKGFLTIN
SQPAVNAEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFPSLTYIAVNKE
GESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGWACLFPEGDS
SRELLEQIQKSYYLVSLVDNDYISGDLFAAFKEI
>A0A432QTJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocapsa sp|TrEMBL
MKSGSNLETLLKEGTFVVTGELGPPKNGNPEVVRKKAGLLKGNVDAVNITDCQTAIVRMS
SIAAGLIAKEEGLEPVIQMTCRDRNRIGMQSDILGAQALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQMLGMMKGMRDDKKFQCGEEIKEHQPKLFLGAAANPFAYPFEYRAVRLGKK
VAAGA
>A0A6A5PEW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lupinus albus|TrEMBL
MKVIEKIRAASSDPDRVVFSFEFFPPKTEDGVDNLFERMDRMVSHNPSFCDITWGAGGTT
ADLTLEISNKMQNMICVETMMHLTCTNMPVDKIDHALQTIKSNGIQNVLALRGDPPHGQD
KFVQAEGGFACARDLVKHIREKYGDYFGITVAGYPEAHPDVIASDGLAPPEGYQNDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KVPADIMAALEPIKDNEEAVKAYGIHQGTEMCRKILSHGIKNLHLYTLNMEKSALGILMV
VSSISCSCDINNLGLIEESKIYRSLPWRRPTNVFRIREDVRPIFWYITFAIAMANRPKSY
ISRTIGWDQYPHGRWGDSDSPSYGALTDYQFMRPRARDKKLVEEWAIPLKSIEDIYERFK
LYCLGKLRSSPWSELDGLQPETKVINEQLEKLNTKGFLTINSQPAVNGEKSDSPTVGWGG
PGGYVYQKAYVEFFCSKEKLDALVIKSKDRSSLTYMAVNKEGSWKSNVGPTEVNAVTWGV
FPTKEIIQPTIVDPVSFKVWKDEAFEIWSRGWAALYPEGDISRKLVEEVGGSYFLVSLVE
NDYVNGDLFGVFADF
>A0A8H5W502|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sp. NRRL 52700|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDRMITRIESHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A7W8ZUB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium roopkundense|TrEMBL
MTVTRIRNTSPTRVPFSFELYPPKTDAAASALHTTIDHLAAAGPDFLSVTYGANGSSRDS
SLDVLRYILAHTNVDPMAHLTCVGSSHAEASVLIREFLDAGIRSFLALRGDPPQGTQEGE
AFLGDLHSAAELVQLIHRVQAERVPYRETVIPGLPGARSVKTEREKVRISVAAFPNGHPR
SRSATQDIDTLLAKQAAGANLAITQLFFHADDFLCFSERARLAGVEFPILPGIMPVTSPG
RLRRILELTGEPLPSELAISLEVEPTAEGQREIGIEHAAGLAAAVLAGGAPGLHLYAFNQ
HETVLEVLRRCGALATAVPEHHPAPTHPAAHVTAHNVRESA
>A0A6A6V6Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporormia fimetaria CBS 119925|TrEMBL
MHISQKLAQARAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPLFIDITWGAGGRHS
QLTCEMVKVAQAVYGLETCMHLTCTDMEKTKLDDALKEAYNAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVKYIRDRYGNHFDIGVAGYSEGCEDNGDVDLLIDHLKEKVDAGATF
IVTQMFYDTDLFLEWVRKVRAKGIDIPIIPGIMPIHTYAAFMRRANWTKCHIPEHWMKAL
EPVKNDDVAVREVGKDLVVDMCRKLIDAGILHLHFYTMNLAQATRMVLEDLDIVPDLESP
LERPLPWRPSLALNRRDENVRPIFWRNRKASYVARTQDWDEFPNGRWGDARSPAFGELDA
YGVGLKGTNEQNIKLWGAPTSIKDISDLFVRYMSKQLDSLPWSEQPIDKEAELIQQELID
LNKRGFLTINSQPAVNGAKSSDLVFGWGPRNGYVYQKAYLEVFVSPEHIAELITRIERDP
DLTYYAVNKDGDLKTNSPDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQDWA
NCHSSVSPSRYVIEDLMDTWYLVNIVHNDFMVTHGIFQLFDGLQVEDMEKPMHTTGTPNG
DAHANGTTEKTVELNGSNGEKTKIEVASDALKSAASALTNGLNGLKVSN
>A0A7C8L4N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces marneffei|TrEMBL
MHVGQKLQEQAATGRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRS
ELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALEAAYNAGCTNILALRGDPPREQEK
WEAAEGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSTF
IVTQMFYDVDNFLNWVEKCRAKGINAAIVPGIMPISTYDAFMRRSNWTKIRIPPDWLEKL
EPVKADDAKVREVGTKLVAEMCRKLLASGHIHHLHFYTMNLAQATRLILEELRLLPSEEA
PLQKPLPWRRSLGLRRRSEDVRPIFWRNRNASYIARTADWDEYPNGRWTDARSPAFGELN
AYGVRLKGTNEQNIKLWGAPKSIKDLSDIFLRYLNGKLERLPWSDSSVTLETSDIQNELL
DLNKRGFLTINSQPAVNGVKSTDPVHGWGPRNGFVYQKAYLELLVPPEHVEELLRRIEKN
PDLTYYCINKTGELRARSDEGPNAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQLGDDW
AKCHPADSPSRKLLQRVMDEWYILNIVNNDFHKNDDIFRLFDGLVIKDFETEVPGTAPEV
ADGTSTN
>Q730T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus (strain ATCC 10987 / NRS 248)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVMPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A373FXL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AM56-10ce|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEIAKIIY
>G2WDX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain Kyokai no. 7 / NBRC 101557)|TrEMBL
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRD
AENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDVKLDLEYLKQKIE
AGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQH
FSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANKCLELWSAPTSINDVAFLVINYLNGNLKCLPWSDIPIN
DEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL
>A0A5C3EQL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ustilago trichophora|TrEMBL
MPSSSTAAAPSTADPAHITTKIQAALARDAPFWSFEFFPPKTTQGLANLYNRIARMRANL
DPSWIHVTWGAGGTTGGKSLELAGRIQKGKLDPDVQLVQSQVQQIGLGSQQHIDNLKGGE
SWQSQDNLDACDVCLHLTCTNVEKSSLDDTLVTAKRLGIKNILALRGDPPRGEEYWVAAD
QRFQHATDLVRYIRENHGDHFCIGVAGYPEGHADYVDRDVKRDLRYLKQKQDAGAHYIVT
QIFYDVDQFLSWYKDCRDIGITIPILPGIMPIQNYQSFRRMTNLCKVQVPQLVLDALEPI
KSDDAAVKEYGVSLSIHMIGRIFLESDVRGFHLCSLNLEKSIERILEGLGWKVDLGAQAE
AEARLNGIPAHLHLERTKNQMLSDRTGANTPKDYKLTTQEALNRTLARTSSSYQVPETST
WDEFPNGRYGDSRSPAFGEMDGYGVSLKVPPQDALRIWGHPVTLSDISTIFASYLEEKIS
CIPWCDAPLMNETLQIRDHLLTLNRPGKSWWSVGSQPAVDGAPSTDPTVGFGPPGGFIFQ
KAFVELFMSTEDKDALISRIDALGPNSQVTYFAGNAKGEFASNLGENEANTVTWAVFPGK
EIVQSTIIERESFEAWREEAFEIWSEWSMLFPKGSASRKLVEGVKEGRWLVTVVHHDYKD
GEGLWRFLAE
>A0A3A9J7J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerotruncus sp. 1XD22-93|TrEMBL
MKRLSEMMKERQLLSFELFPPKTDKGMENLPGTIGKLCEFEPEYISCTYGAGGTNVGKNL
DVCQMIKEAGTTPVTHFTCIGNTREGIKEQLENYLKNGVDHMLALRGDLPFGWTGTGGDF
KYATDLVAFVRKEFGDKFEIAVAGSPEGHISCRSLDADVAVLKQKQDNGADYIMTQLCWD
MEQFKRWQDKLDRAGITMPVDVGIMPILDQAATINMALSRNACVMPRALCELISKYWIFP
NPFDKEPFDAAVDQKKADFKKAGIEYTIKQIDEYRALGINGIHLYALNKWKDVTDIINES
GIKTMV
>A0A2W6XE53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MAAPALNLAEARALLLSPLGPVARAGSNHNAVNVSFEFFPPKSDEAEANLWKAIRRLEPL
NPAFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRDEVDEVIQGYKAIGV
DHIVALRGDPPGSAGIGGAYQPRADGYANATELTAAISRIGGFEVTVGAYPEKHPESPSI
DHDIEVLKAKVDSGATRAVTQFFFDIEAFLRFRDRVRSAGIKIPLVPGIMPVSNFAGLKR
MTAACGAALPDWLAAHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAEL
VYAICRVLGVREHKAVA
>A0A2U1QU55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. NDM|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETADHFHIEVAAYPEMHPQARNYEDDLANFVRKAKAGADSAITQYFFNADSYFY
FVDRLQALGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTRSIQSFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A3B9RIV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MMTGSSTNLAEARALLLSPLGPVARAGSNRETVRVSFEFFPPKTDEAEVNLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIIAETALRPAAHLTCVDASRDEVDEVIAGYKTIG
VDHIVALRGDPPGGGGIGGVYQPRADGYANATELTAAISRIGGFDVTVGAYPEKHPESPS
IDHDIEVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLV
RMCGACGAGIPDWLKAHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETKAVA
>D3PYE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)|TrEMBL
MSMSAALSRVRMRRTASRLLAEPRFEVLPLERVDREVAALPRGTTVTITASPSRGTMATV
ETAERFAALGLRPVPHLSARGMRDDAELVEVVQRLDHAGIRDAFVVGGDASSASAVFPDG
LALLQAMDDIGHRLHDIGIPAYPEGHPSIDDDTLWAALAAKRRYATYAVTQLCFDAEAIC
RFTVQARQRGFDLPILAGIPGAVDTAKLLRVGLRIGIGDSLRFVRGNRSVLRKLLRPGGY
RPDGLVRKLDGRVRDGRCELAGAHIYTFNDVAATARWLKGRTAVYDHAQ
>A0A6H1F102|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemella haemolysans|TrEMBL
MRNLLERLEQNVLVADGAMGTALYSNGLESCHEYNNISNPDSVEKIHKAYIEAGADIIQT
NTYAAKKCQLKTYGYDDKFEEINIRAAEIARKAAGEDTIVFGTIGAIRGLRECELSLETI
VKETIDQVKVLLSTNKIDALLFETYYDQEEIRAVLTEARKITDLPIITNISLLEAGITQN
GEKVTDALSALVNLGADIVGLNCHLGPYHMIKSLKQVPLFAQSYLSAYPNASLLQLTQTI
NGNEYRFRKNSSYFEQSAKLLVEEGVRLIGGCCGTTPEHIRAIKKGIKGLKPVKRKVITP
LPAEEELVRVANNKPTIVDKVKKQVTIIAELDPPKHLNVDKFIEGAKAIDKKNIEAITLA
DNSLASTRICNLSAATLLKEHITTPTLLHLTCRDHNLIGLQSRLMGFDLLGINNVLALTG
DPSKLGDFPGATSVYDMTSLKLIPFIKQLNEGLGYNGASLKKTTNFTVAAAYNPNVRDLS
KTKRLVEKKIKAGTDYFITQPVFEAEKIEQLAELAADYPDTPFFVGIMPITSYNNAVFLH
NEVPGIKLSEEFLAKLEEVKDDKELCQKVALEESKKLLDVALKHFKGIYLITPFLRYDLT
LELIDYVEENKDK
>A0A6J4HEZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Acidimicrobiales bacterium|TrEMBL
MARISDLLAAGRTVSFEFFPPKSDAAQAQLVRTLRELETLEPSFVSVTYGAGGSTRERTH
GLVVGMLNTTTLTPMA
>A0A843RIK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiloniellaceae bacterium|TrEMBL
MKLQTRQQILDLVQDFTLETTPGSALKIPDYREHLRPGARVAVTFLPGSNFADTVATAKR
LQEEGFEPMPHFAARSIPSRQALEDYLKALADVTDLRHVVALAGAVDKPLGPFESSMAIL
DTGLFDKYGVETIGVAGHPEGSPDIAPAVLQEALAWKNAFAERSDAALYIATQFCFEAAP
IIAWDKAMRAAGNRLPIHLGVPGLATIKTLINHAKACGVGPSMRFLTRQARNVAKLMTVN
TPDRLLLDLARYKAYDPDCSIARIHVYPLGGLRRSAAWTYAVADGDFDINAKGDGFKVTR
EIE
>A0A6I2FVP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia sp. SYP-A9097|TrEMBL
MLNPDNTFGSPHQRTRISPITSGVPSVVKSLRSHSGPRVPFSVEFNPPRDAAGEARLWRA
VREFERMHPAFVSMTYGAGGSTKDRTARITGQLARETTLLPVAHLTAVGHSTAELRSLVG
SYADYGIRNILVLRGDPPGDPLGPWHKHPQGVEYADELVRMVRDLGDFNVGVASFPQGHP
RSPDLATDTAFLAAKLRAGADYSITQMFFDVDEYLRLRDRIMAFDPIEGAKPIIPELMPI
TSLRTVARAEELSGRPLPPQVLQRLHRAAGNGPEENQAAIREAGIEIATEMAQRLIAEGA
PCLHFITLNFAKATREVLDNLGYQATATPLSA
>A0A3M2HT96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter pythonis|TrEMBL
MLPISFEVYPPKTDDQRAQLDRAMSKLKTFAPHFVSCTFGAGGSTQSHTSETVQRLRASH
GLEGVPHLTCVGASREDIRALLRLYRALGVRRIVALRGDLPSGTLDRGDLRYASELVRFI
HDEHGGHFHIEVAAYPETHPQARDALADLDHFKRKVDAGADSAITQYFYNADAYFRFVED
ARARGVEAPIVPGIMPISNFSQLRRFSESCGAEIPRWIEQRMRAFGDDTGAVREFAADLV
AAMCRRLIEGGAPGLHFYTLNLARPTMNVLSRIRTA
>A0A178ZJ86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fonsecaea erecta|TrEMBL
MHVTKKLELAHQQNKPTFSFEFFPPKTAQGVQNLYDRMDRMHNLGPAFVDITWGAGGRHS
QLTSEMVNASQNFYGLETCMHLTCTDMERHQVDEALRRAYKAGCTNILALRGDPPRDQEK
WEAKEGGFRYAKDLVKYIRARYKNHFDIGVAGYPEGCDDQRDVDVLIDHLKEKVDAGASF
IITQMFYDVDIFLGWVKKCRDRGISVPILPGIMPIQTYAAFVRRANWTKCHVPPGWFEAL
EPVKNDDAAVRAIGKDLVADMCRKILNSGIQHLHFYTMNLAQATRMVLEDLSLTPETSGM
PLEKPLPWRQSLGFNRRDETVRPIFWRNRNASYISRTADWDEFPNGRWGDSRSPAFGELD
AYSIGLKGTNEANIKLWGKPKSLRDVTGLFVRFLQGDLDRLPWSEGAISAEADVIKDDLL
QLNKHGFLTINSQPAVDGASSTHPVYGWGPAGGWVYQKAYLELLVFPSMFKAVMDRLNAD
KNLTYYAVNRKGELYTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WANCYPAGSGSRKLIEKIMDECYLVNIVNNDFHQNKEIFKVFEGLETKDLDLVIDDNASG
HIENGTKDVPNGDAEKGLTNGAQRKAPVKADGEVLSN
>A0A0M4H958|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. TTH0-4|TrEMBL
MTKRVPFSFEFFPTKTDIGAEKLRVVHQELQLLKPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFKIEVAAYPEMHPQAETFDKDIQHFVEKVKAGANAAITQFFFNPDAYFYFI
DRLAKQSIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVLKLSERLIAGGAPSLHFYTMNHTEPNRQLILDLGLA
>A0A374V6F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. OM08-11|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHLLCSGFSCEDIEYELLDLQFLGITDL
LVLRGDKAKHESVFTPETDGHSHAIELEEQINNFNKGIFVDGSEMKVTKTPFSYGVACYP
EKHEESPNMASDLYWLKKKMETGAEYAVTQLFFDNQKYFHFVERARKEGITIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTHEALKCKTDADAQEVGIEWCIKQCKELMIHGVPSIHF
YSIGAVDSIREVAKQIY
>A0A291LXU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pacificitalea manganoxidans|TrEMBL
MTADQSQTRPDAPRVSFEFFPPKTLQASFRLWDTVQALAPLNPEFVSVTYGAGGTTRKLT
HEAVDAIHKNSGLTVAAHLTCVEATREETLEIARSYLDAGVRDIVALRGDPPKGQGRFTP
HPDGFADSCELIAALKETGDFRIRVGAYPDTHPEAADADADVAWLKRKIDAGADAAITQF
FFESDAFFRFRDRCDKAGITAPILPGILPIENWTSARRFAASCGTVIPAWMDEAFETAAA
NGSEDETATRIATEMCETLRAGGVDDLHFYTLNRPTLTRDICLALGVEATPDTLGRVA
>A0A436ZSE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobotrys flagrans|TrEMBL
MQEKVTDKIKALPKDATYFSLEFFPPKTPAGLQNLHARLDRMAKGLRPLFVNVTWGAGGS
TATKSLELASLCQSLGLTTVLHLTCTNMSKSVLDDALENAKLMGIRNILALRGDEPRHHE
YLDATEQVRNGGGDNEFVYAVDLVKYIRKQYGDYFAIGVAAYPEGYAESAYPVAQDTSRD
LPYLREKTAAGADFIMTQFFYDVEAYISFEKVLRTDESGVFKDIPIIPGLMPVQSYQIFK
RTTKLCSVKVPDGVSTRIESVKADDEMVKEHGIRILTEMIDKIRNSTETGGGLPRGFHFY
TLNLEKAVAFIVERCSLIPEIPTSNEVAVEDEEDEGPGLLTVNGSGAAIPRRSRRTSSII
SDPHNRVIVDAVSSARSELQAEAGEAGVPKILDPGSQEGNLAISEGEGSLGREATWDDFP
NGRWGDARSPAFGEIDGYGVSLHRTPTEALRLWGKPTSTKDISDLFVKNAKGELEAMPWS
EDSLNPESFLITEELVKMNARGWWTVASQPAVNSAKSDHPTFGWGPKNGFVFQKAFVEFF
IPDDEWTGLRKKLEAEGKEDVSFYAGNKAGDFQTNMASDSSLNAVTWGAFPGKEIVTPTI
IEEVSFRAWRDEAFDIWSEWQRIYPLSSATSKLLGELKNKLWLVTIIHHDFVKADGLWKD
ILGL
>A0A448GX84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella cuniculi|TrEMBL
MTQSLLNRLNDIETLLNSVKSELQNQTKPNNTNNKVPFSFEFFPTKTDEAQDKLLTTFDT
LNALNPQYFSVTYGAGGSTRERTLGIVEALSKQSDTPIAPHMSCIGDTKAEIGELLDFYK
SLGVTRVVALRGDLPSGQVGYGELPYALDLVKFIRQHSGEHFTIKVAAYPEMHPQARNFD
ADIDNLVAKYHAGANEAITQFFYNADSYLFLRDKLAKKGVHQDQFPIIAGIMPITNASNI
IRFADGCGADIPRYIRKQLADFGDDRKAIRQFGFEVVHTLCQRLIREGVPALHFYSMNST
EPNKELVKALGLTS
>A0A3E2U7D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MTDIREYLARKPLLFDGGMGTYYKAAPGADCEMANLTDPEGVKKVHAEYLAAGAQAIKTN
TFGLPRMAAAQMPGWEELAEAGWKLACDAAAEKDAAVFADLGPAPDTEAAPASSAYGLVA
QQFAALGAKNFLFETLSSDVGIVEAVKALRVAVPDAFVMVSFAVLPDGYTREGLLFRDLL
RRMEQSGVVDAAGLNCVSAPGAMKKLVQGLGETLLPLSVMPNAGYPVVTRARVLYQGKPE
YFAREMGQIAAAGVRILGGCCGTTPAHIAALRAELDALPQQTEAAPAAKLSTGTAPAVEK
DDTFLRKLNAGEKVIAIELDSPRVADLSGYLDGARRLQAAGADLLTIADCPIAQARMDSS
LVACRVHQELGMCALPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSAMTVFGALNLNARNFDVELRRAVEKLENGMSGFL
TQPVLSAQAVENLRKARQTLGERAKILAGIMPVVSQRNAIFMENEINGIHVEEDIIQRFA
GLDREQGEALGLEVSMQMAREALPYADGFYLMTPFNRVALMERLIARLKTELLDAEG
>A0A2N2GI07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-6|TrEMBL
MQSNRFKEALLNPSEFPVTWELVPGRGAKEAAQEKALALAGQAATGGKIHALTLTDNPGG
TPAMSADFMGCEILKLGIEPLVHFTCKDKNRNQMESQLYALDRAGIRNLLVMSGDYPASG
FQGRPAPVFDLDPIHTLQLISDMNRGLTYPGIKGNIIHQTSDFFPGAVVSPFKATEAEQM
VQYYKLKKKIAAGAQFIVTQLGYDARKFHEVLLFMKQNGFNIPLVGNIYILPFGAAKMMN
RNDLPGSVVTDKLLADIDRERNDPDKGEGARILRAARMYAIMKGMGFSGVHIGGHNIKYE
QVEAIIRQGEELAPRWTELIRYFDYPIPDGFYYFERDPDTGLNRETATTRQNRPLDARIE
FPYGFSRFFHQVMYEPGKKLYGVMKSLCTKVEGTKMEGFFHKLEHLTKVALFDCKDCGDC
ALIDAAYLCPMSQCPKNQRNGACGGSFRGWCEVYPGKRQCIYVRAYSRLKKYAEESQLDR
DIVPPCNWDLYQTSSWINYYLGKDHTSKRQNSHPSGK
>A0A734I044|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 58:l,z13,z28:z6|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A372SVU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Absiella sp. AM09-45|TrEMBL
MAQQKGMDLFKEYQAIVDIFLSLGANRFLFETFYNDIALKEICAYIKEKSPQSYIITSFA
LSGDGYTRQGISGEKLLMEMDTCPYVDAIGMNCICGPMHLDRILQGLSIKHHKISVMPNS
GYPTILHNRTFFRDNSTYYANAMMQIITHGASIIGGCCGTTPAYIKAIRKQLKIQSPKVE
SSTKEIKNDKKEIIDHDPFHQKIKRGEKIIAVEFDPPNHCDIEHFMDNAAYLKQAGVDAL
TIADCPVARARVDSSLLACKLHREMGMHVIPHMTCRDRNINATKALLFGLQIEGVHNVLV
VTGDPIPAEDRKQVKGVFNFNSQLLAGFINDLNQTTFPQPFLICGALNINAVNFKAELEK
ARKKEKQGVTAFMSQPVLSKQAYENLKLAKQALSSKIFGGIIPIVSHRNAVYMNNEISGI
DVDQEIIDLYVDKDRTQASELAVTISCEIAEKIYDLVDGFYLITPFNRVDIIGSIVAHIQ
SLSN
>A0A257CKD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium PBB6|TrEMBL
MSVSDDFQLSLEFFPPKTPEGVTKLAAVRSELYALKPAFCSVTYGAGGSTQDGTLQTVQS
ILSEGHAGAPHFSCIGADAATIRERLAQFKAIGVKRIVALRGDLPSGYGGFGEFRYASDL
VAFIRAETGDHFHIEVAAYPEMHPQARSPQADLQAYATKVKAGADSAITQFFFNSDAYFR
FVDDAYALGADIPVVPGIMPITNASGILRFADSCGADMPRWIRLRLQSFGDDSASIKAFG
LDVVTDLCDQLRTAGVPGLHFYSMNQSATVLEICRRLNG
>A0A1G7DTS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas thiophila|TrEMBL
MLMKQILDRQQPSLSFEFFPPQTPAGWQALEQEIAALVPLQPTSVSITYGAGGSTRDQTH
KLVLRIQRQTGITVVPHQTCVAASRQEVREILTRYQNEGIENLLALRGDPPRDQPNWQPP
ADGFVRAADLVRFVRQEFPTMSIGVAGFPEGHPATPNRLLEMEYLRQKVAAGADYIVTQL
FFDNRDFYDFCERCELAGIRVPVLAGIMPLRSRKSMERLAELAAGARFPAALLRRLAAAA
DDGEVERIGIDWATAQVADLLGQGVRGVHFYTLNSAAATREIFRRLGLPAACQGE
>A0A0S8FB70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium SG8_31|TrEMBL
MHQPPVVSFEFFPPASEAMEERLYASVRRLAPLRPQFVSVTYGADGSTRERTHRVVERIV
SETDLTCAPHLTCVGASREQVLDIARQYADMGIRHIVALRGDPPAGSKTYRPHPEGFAYA
SDLVAGLKTVADFEITVAAYPEVHPEATSPLGDLENLKRKIDAGASRAITQFFFDNERYL
RFRDLCVAAGIEVPIVPGLLPITRFPQLLKFAGQCGASVPEWLRQRFEGLDDDPETRQLI
AASVAIDQVQFLRRHGVEEFHFYTLNRSELSYAICHTLGLRPVPNARSA
>A0A4R3FCU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK376|TrEMBL
MSQIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADAEDVYERASIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANMMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNGKFLSGRKLTKPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGFHEKCFILVGV
GPLASARTAKWMRSNVPGVHIPDDIIKRIEGAEDQKKEGKQLCIDIINEVKEIEGVAGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREANRGDELVAERMEHIREGKEENQQEMAEIAA
HHVPTH
>A0A2M7R1Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium CG_4_10_14_0_8_um_filter_41_23|TrEMBL
MGFKEVLESKKFVVTAEIGPMKGTDVQETLEDAELIKGKVDAINVTDLQSSVMRLGSMAV
CHLLKDHGIDPIFQMTCRDRNRLALQSDLLSAWVLGIRNVLALTGDYPTVGDHPQAMPVF
DLDSVILLKVISRLNEGFDMAGNQLKGATDFFSGAVVNPGADTEAALEMQIIKMEKKIEA
GARFFQTQGIFDLELFEKFMKRIEGFKAPVIGGVILLKSAGMARFMNKNVAGVFVPEPLI
KEMEEAKDKVKTSIEIAARLIKGMKDICQGVHIMAIGWEKKIPMVLKEVGL
>A0A845MEA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sneathiella chungangensis|TrEMBL
MTAAAHDHGAQLPPLPGHTSRGRLERVLRAGEFAVTAELNPPDSADPNEVFERGAVFDGW
VDGINATDGSGANCHMSSVGICALLTRVGYSPVMQISCRDHNRIAIQGNVLGAAAMGVNN
ILCLTGDGVQAGDQPGAKPVFDLDSMSLLRTIRQMRDEGRFLSGRKITSPPQVFLGAAIN
PFAPPYDFRPHRLAKKIEAGAQFVQSQYCFDIVMLERYMEMVRDMGLDEQCFILIGVGPL
ASARAAKWIRANVPGIHIPDAVIERLEGAADQKLEGKKICIEMLQQVHEMKGVSGAHVMA
YRQEELVAEIVHESGVLKGRRPWKRENNPDFEAVSGAFESVKEQIRHPVDPAEAVAAVSE
EH
>A0A1V4IFV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium chromiireducens|TrEMBL
MIKKYLQNNVLISDGAMGTYYSELTGNDASYCEFGNLNDKDTIKRIHTDYIKAGAKLIRT
NTFSANTYDLGVSFERLKDIIKSGVDIAKEAAIGNDVFIGASIGPIKELNLDESHSSILD
EYKFIVDCFLSSKINVFIFETFSNCNYLKEISEYIKSKDSSSFILTQFAVKPDGFTRDGL
SVGKIIKLIKKIQYLDAYGFNCGSGPNYISEIIKKINIGSDIVSALPNAGYPEIIHERTV
YPNNPAYFAKKVNEIKSLGVSIVGGCCGTNPNYIRQLASLIDDKSKKIKNIVKNEEEIKK
YENKTENAFKNKLDNNEFVVAIELSAPIDTDISKLIVGAKICKENNIDLVTVPDSPMSKV
RADSTIIAAKIKREIGIEAMPHICCRDKNTNAIRSSLIASHIENVRNVLAITGDPISDAS
KVETKSVFNLNSFRLMELIQDMNEEFFKEENILVGGALNLNVRNKEVEYNRMLKKIEKGA
KFFLTQPIYDDDAIEFLKKIKERTDIKILAGLLPVVSYRNAVFLNNELPGVTIPDKYIKM
FNEDMTKEEAQEVGVKITVEIGKKLKDFCDGLYFITPFNRVNMLVEIIKQIKG
>A0A7C6GK96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKLTRLFAEGGPALSFEVFPPKAGNNYESVRSATEAIAGLRPAFMSVTCGAGGSTEGFTV
SIAKNLKDKFGVTPLVHLICISSTEQEIESSLLQIRDAGIKNILALRGDMPKYDQAAIKK
DFRYACDLVAKIKRFGDFCVGGACYPEGHPEAPNFDEDINNLRVKVDAGCDFLVSQMFFD
NNIFYAFLDKLAAKGINVPVIPGIMPVTNAKQIRRILELSGRTLPRKFAKIVERFGDDPE
AMKQAGIVYATEQVVDLYASGIKNVHIYTMNKPEVAARVMDNISAIIKTQIFGRSTARGI
K
>A0A7Y9SV22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. JAI108|TrEMBL
MTSNLNSLAEARRAAASPLFANLDGDIGVSFEFFPPKTEKMEAQLWDTFRALEPLAPSFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASRAEIDEVARAYWEAGVRHIVA
LRGDVPGGEPYRPHPDGYANAIELVAGLKAIAPFDISVAAYPETHPDADCPQADLDNLKR
KLDAGATRAITQFFFSPDSFLRFRDAAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMVSLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVSTAKDQAA
>A0A151BW32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Branchiibius sp. NY16-3462-2|TrEMBL
MPIDRPAATSSRPLIPDLLRRAEPAFSFEFFPPKDDSAETLLWESIRRVEPVAAFVSVTY
GAGGSTRDRTVRITGQIEARTTLTTMAHLTCVGASVADLRSVIGAYADAGIRNVLAVRGD
PAGGLGTPWTPHPGGLDHADQLVGLVRGLGDFTVGVGAFPDRHPESASLADDVEVLVRKA
DAGADFAITQMVTDVDAYLRLRDEVAQRRPDFLVVPGLLPVTAYGQLQRMTKLNGQPLAQ
SVLDRLEAVQDDPDAVRAEGIAVCTEHAGRMLQEGAPGVHFITMNRSTASLEVVSNLGRR
ANVPAAS
>A0A1R3WUA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibaca methylaminivorans|TrEMBL
MTRPEISFEFFPPQTLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRDLTRDAVATLHR
SSGLRVAAHLTCVNATREETLGIARGFAEAGVKELVALRGDPPKGSGPFAPHPDGFANSV
ELITALAESGDFTIRVGAYPDQHPEAANAQADIDWLKAKLDAGASEALTQFFFEAETFFR
FRDACAKAGIDHAITPGILPIENWKGARNFARNCGTHIPAWVEDAFGNARNKDEEDLLAT
ALCAELCSDLIAGGVDKLHFYTLNRPELTRDVCHAIGVTPRRPLKKVA
>A0A424SMJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium TMED46|TrEMBL
MRIRDKIKKPQXPVVAYEILPPXEEDGTLNSXAETIXSLLSQTHIDAINIPEVHDEVGRG
DRPVANQKRGEPREFGMLLQDIVGIEAIINRVVVHEPYDKQXQWFEETXTKFEIENMIIV
GGESSKVSYPGPSVNEILDAITNQHNQNGGNILCGGIAIPSRKQESKNLINKSNNGSEFF
TTQVLYDSENIIKMIXNYQTRXNELNTFPRRILLSFAPVSSQKNIEFLKWLGVEXPTNTE
HYLQAXPGSMTERSLDVAIEVLNEILNHIEKNXLKVPVGXNVEHIMSXNFQSSVEMLQEL
ARIYREFCIKSQQYS
>A0A2U8FES3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter apodemus|TrEMBL
MTNTCLIEDFINKLKNSQKCFTYEFSTPSSFSLESFYDFSDSLLQQLDAFVCTDSPLAKL
KHSATLASLKLQNTFKIPSITTMSMRDRNTLSLQSELIGMNSLDLRLVLALTGDPLRLGN
QTQAKGVFEGNSNLLLKIIKQLNQAKDINNQNISGKCKRIYPFSVLNAYPNKKETSYKKM
KEKIQNGAEAIFTQPIYDLQIAKELISWNKEINQECKTQSVLVLGFFPITSYKTALFLHN
KLPGVHVPQDWLNALEKAHNNEAAIGLAKSKNFFEKLRCFYQKIHFMSANKPKLIENILC
>A0A401M9M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NL15-2K|TrEMBL
MTAATGTRGTAVIADHSIEITGKDVAALGEVAAHFNPGTAVNVTYLGNESLSVRIEACRA
ARGHGFRPVPHLAARRITGEAELRQFLSALREVGANEEVFVIGGDPAEPHGPYGDALALI
RTGLLQEYGVRHVGITGYPEGHPHIDDSALWDALEHKIAAATEQSMQVSVTTQFGFNSET
VIQWIELVRGRGITVPIRVGVPGPASIQRLLGYARRFGVKSSAGIVGKYGISLTRLVGSA
GPDRFIDSLAGRLTPDHGPVLVHFYTFGHPAATAAWVSARKERIR
>A0A455U0Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sulfidaeris|TrEMBL
MVRAVSESGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRY
ANELVEFIRAETGDHFDIAVAAYPESHPQAANLDKGCGKFCTQNEGGGQYGHYPILLYR
>L8P2I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces viridochromogenes Tue57|TrEMBL
MHTAGLRALLHSVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLAARLASH
GYRVVPHVPARLLRDDLHLKDVTGRLREAGVDDIFLPAGDADPPAGVYDGALPVLRRLSE
LGRPFAHVGVTGYPESHPLLHDDVTVQAMWDKREHATYLVSNLCFDPRMLGEWITRVRRR
GVALPLYVGVAGPVQRAKLLAMATKIGVGESTRFLTKHASWFARFAAPGGYAPERLLTRT
EKALTAPSARVAGLHLFTFNQIAETERWRRALLDRLGR
>D3ABJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi DSM 13479|TrEMBL
MKISELYQTKQNQETPSKKTLSFEIFPPKKDSELKNIDKTLSVLCELNPDYISVTFGAGG
GANRNRTIELAKRIKQEYHVEPVVHLTCLHYDKAEIDEFARVLTNAGLQNVLALRGDKNP
NMREKESFLHASDLIAYMKDKWDFCFLGACYPECHPESEDKVCEIKHLKAKVNAGAEVLL
SQLCFDNHAFFRFQEACRIADIQAPVIPGIMPVINAAQIKRMITMCGATFPVRFQKIIQA
YESNKEALFDAGMSYALSQIIDLLVSDVEGIHLYTMNNPLVARRICEGIRNII
>A0A3B9I3H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MFIKDKFIKKNKVISLEIFPPNSNMTLKQLLDVIDDLAVFRPDYISVTYGASGNANNDYT
IDIAEYIKEKYTIEAMPHLTCITSKKEKVDEILQLIIKKDLKNVLALRGDKPKDGLMNQS
NRMDFTYASDLIEHIRSSELPVSIAAACYPEGHIEAPSLNEDIRNLKTKVDKGVDFLITQ
LFFDNERFYDFKDRLTKNSINTPLTVGIMPITNVKQIKRIVSLSGASVPPKLKLLLDKYE
NDNLGMFQAGIEYACQQMDELDQWKVNGFHLYVMNKPEIAKMIYKNMNW
>A0A4U8YQA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoluna butyratoxydans|TrEMBL
MTHKRFEVVVEVVPPAGADVEPLLSALEGINDLSFTGFSVATNPVAKPRMDALSLCRILQ
DELKRPATLHVTTRDHNRLSLQGILWGAKALGITTVLAMTGDFVPLAEKGMTSSVRDISL
TELIGMARQAGLNVGVVMNPFTDELRLGIAVKRLKEKVAAGAQFVVTQPVYTAKDAEILA
GALNPLGIPVMLGILPLRTFRHAAFLHHKVSGIEVPDEVRSAMATAENPTAEGIRQARDL
LTAARTCFDGVCIMPPFDHFEILHGVLPREGGDAG
>A0A354USA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MRITELFDNGEFVVTAEVGPPKGIHIGGMVEEAKEYLAGVHFVNVTDNQSSVMRLGSLAT
CKMLKDAGLNPIFQLTCRDRNRIALQSDLLSAAALGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHAASVLETGKDLGGNDLVGEPPKFAKGAVVSPCSDSVDAQLVKMERKVAAGA
QYFQTQAVFEPEKFIKFMEQAKQFGKPVQVGIIIPKSAGMCKFMNKNVAGVHIPDALIEE
LQADKERTKAGITGVEIAARIIRECKPYCQGVHIMSLGWESKVPALLEQAGLK
>E7C6F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Planctomycetales bacterium HF0770_03I01|TrEMBL
MPAQGRPNPDKILNKIKTGVDFFQTQYVFDTTILKEYMKVLDHSGILEKASFIIGLGPFT
SAKSAKWMNDNLVGVEVPVEIIKRLKQAKDQKEESQKICLELIQVFREIKGVHGVHIMGH
NKEQVIAEIIKKSKKN
>A0A7C7JC34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNTSFEFFPPKTEKGKENLINLIKRLSHFSPEYFSVTYGAAGSTRKGTLETCVSIKNLGQ
NTCPHLSGIGSSKSVIKEILNEYKGYGLTRVVALRGDLPSGFGGFGDFPYALDLIKFIKR
EQESFSIEVAAYPEVHPDAESENTDFENFLNKVEAGADGAITQFFFEEDSYFKFVEKCEK
ENVTIPIIPGIMPIHDFESLVRMAKNCSANVPLWLKEGMQKYSNNEDRLMYGVEVITKLC
QKLLRFGAPGIHFYTVNREEPTSLIIKNLESK
>A0A200P005|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella flexneri|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCISAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0S8JPE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division TA06 bacterium SM1_40|TrEMBL
MSADAGGRGVSEKAKPSRDLLARLRTQVLLCDGAMGTFLYSKGIPTDSSLEELNLSRPSL
IRDLHAAYAEAGADILETNTFAANRAKLGMHGLEGEVGRINECGARLAREGGGPEVLVAG
SVGPLGALIEPYGRLTSETARQMFSEQIRSLAAGGVDAIVVETFSNLKEALEAVRAAREC
CDLPLICQMTFLEDGSSQFGHRIRPSFDVLIDAGADVVGINCSIGPRAIHRLVVDHLGGT
SYPLSVQPNAGYPAIINDRSVFLSTADYFRDYAEEFVELGVNIVGGCCGTTPEHTAAMAE
VVRGRTPRRRHSREPVEHRVPVSVHVRGSRDAPAVSGVAPTSRFLEKLGEEFVVTVEVAP
PRDIEPSGLIESVRRLCLAGVSAVNVAENPLARLRMSSLAFAHLVKEQAGVETILHVTCR
DKNLLGLQSELLGAAVLGVGAVLALTGDPSSIGDFPRATSVFDLDSIGLVRMIAALNAGT
DIGQNPIGHPTAFRIGVAVNPAAPDLAHEVARLEEKIEAGAQFAQTQPIFDRSILEEFFA
RCGHLEIPILVGLLPLRSAKQAEFLHNEVPGISIPDEIRASMRAAPPAEQGQCGVAIARE
LAREIREQAHGLYLVPTGARFDNVLEVLKY
>A0A6N9BZR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPAPRKGARGSRAPSPGCAAVTRRTRSAGPRPSRNSTRVKRGDACASRRSGVPAVSRLSQ
SLADEDFTLTAELNPPKGTDLAGVLSAAETLKGQVTAFNLTDSAASRMTMAPGALAHLLR
DRDIESTLQIAGRDRNRLAIQADMLAASALGVENLVCMTGDPPSGGDHPDAKAVFDLGAE
DILKAASSLEAGQDLAGNALKGRPRFYKGAVANVAVPDLGKEVARMEAKIASGAQFFQTN
AVYEAAGFETFMQRCEKFEVPVLAGIIVLKSARQARYMTERIPGVVVPDRLTDALARTSD
TVRTSVRMAGQVIRDVAPMCHGVHIMAIGWERYIPDVLEAAGR
>A0A7W8JLB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. ANJX3|TrEMBL
MPAISFEFFPPKTDEQRAQMDRAAASLKTHQPEYASVTFGAGGSTLSYTTETVQHLNKVH
GLSVAPHLSCMGGSRAELSALLDDYRNAGYRRIVALRGDLPSGMATPGDFRYAAELVAFI
RQHSGDHFHIEVAAYPETHPQADSALKDLLHFKAKVDAGANGAITQYFFNADAYFRFVDD
ASKLGVSVPIVPGIMPIANYSQLRRFSEMCGAEIPRWIAKRMQAHGDDAESVRALGTEVV
AQLCRRLLDGGAPGLHFYTLNRAKATQSVLQQLG
>A0A6L8EEL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MQFEDEPVTPGDPLPIRPGHSSFGRLERVLRGGGFAVTAEIAPPDSANPAEVYKRAALFD
GYVDAMNATDGSGANCHMSSVGMCSLLTRRGYAMVMQVSARDRNRIAIQGDILGAAAMGV
ASILCLTGDGVDVGDHPQAKPVFDLDCMSMLNMIRHMRDESRFLSGRELTEPPRVFLGAA
ANPFAPPLDYRPHRLAKKVAAGAQFVQTQYCFDIDAFRRYMDAVREAGTHEKVFILAGVG
PLASARSAEWIRGNVPGVHIPDAVIRRLKTARNQQQEGVNICIEMIHQIREIHGVHGIHI
MAYRQEHRVAEIVERSGVLGGRMPWRPAVDWKNAEWDQGHPVATHTPDRQVLESVS
>A0A8I5TPB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pongo abelii|TrEMBL
MCRGCGCLPPDAPCPTPCSRNPAMVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGL
DPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHP
AGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALR
GDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEK
VSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVP
QEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLG
MWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAF
GELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND
EPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFT
SRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDP
VSFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVE
DTLELLNRPTQNAREMEAP
>A0A521XVR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKIVQLFNVSFEFFPPKSAEGVQQLVETASLLAEHHPHFFSVTFGAGGSNRAGTMESVKL
LQQYTGIAVAPHLACIGSSRTEILEMLQAYRSIGVRRIVALRGDL
>A0A5N8YT86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium AD-802-K11_MRT_200m|TrEMBL
MSTLVELVAKNRRRPFIVCDVSPPRSGNTEALSALSSVTPDMFFVAANPGRTVRASSPSI
AQWIESDIKTPALFTMVTRDMNKTAMQTTLLGAHIMGLRNLVVVKGDNFNNSGCGTDKPV
EGFTPTAFIRSVRKMNNRIDFTGRSLTDPTQFCVGATLDISRKWCSEMSLADNKIRSGSD
FLIAQPNFDPDAAHKFLQEYQERRMSEMPIPIIWGIQIMSKGSISFANVPDHITKELDLG
NSGYEIALEMIHRYLEIGINYFYLVPPIFQGGRRDYESAQAVIEDL
>A0A523JR81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTFQEAIRTQDFTLSAELRLDSHSDAAAIMEQARILAPAVDAMQVTDNPGGRVHLSPLI
AAGILLDHGIDPVLHMTCRDRNRIALHSDLLGAAALGVTSLLLMRGHKISEEPLSRAGTV
FDWRAKRLIAAANSLRTDPPFAKPVNFLIGSIATAFNPHRNWKPEKIKAKVDAGVKFIQT
QLCFDVDLLRRYMARLVSEKLIERVDVIVGTAPVPSAEVARWLGKNLRGAVMPRRIVTRL
RQSTNPKREGELICAEILHEAAQIPGVSGANLTSFGAADSIVEAVEISGIRS
>A0A353VYS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MESQKKYSPKFSFECYSPKTPEAIANLQNAQLELASLKPDFFSVTYGAGGSTRNMTFETV
LDIREKTGFESVPHISCIGNYNDEINAMLQSYIDNDIKQIVVLRGDLPSGTVGYGQYQHA
NELVEFIRKQTGDHFHIEVAAYPEFHPQAASPKVDIDNFKRKVDAGANGAITQYFFNPFS
YYRFIDHCEKLNINIPIVAGVMPITNCTQLVRFSEGCGAEIPRWVLKQLQGFGDDRESIF
KFGVDVVTELCDQLLSNGAPGLHFFTMNKSAASIAIWKNLGLDKRTIK
>A0A0A2XBI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallibacterium genomosp. 2|TrEMBL
MSYAKEIDVLNRSIADLNGDINVSFEFFPPKNEKMETLLWDSIQRLKSLQPKFVSVTYGA
NSGERERTHSVVKAIKQQTGIEAAPHLTGIDASPEQLKAIAKDYWDSGIRNIVALRGDEP
PGYDKKPFYAKDLVKLLKEVADFDISVAAYPEVHPEAKSAQADLIFLKQKVEAGASRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFVQLQKMAKVTNVKIPSWMFKLYDGL
EKDQTTRNLIGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGVRPSLAA
>A0A3D0ZZC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTIIESDPKARRNYIHKLLSNASIEALPAQVITTPEIVQPLPSAPVFVPFLPGSDLDSTI
IATRNLVSMGRKAIPHLPARSFQSRDHLSDWLAAIRSTDTKHLLLIAGDTQFPLGPFKDT
LDVIDTGLIEQHDIERVFIAGHPEGHPLVAPKVLYDALTVKKAWSEAMSIELHVVTQFTF
DIPQFINWLDQVNQLTNSIPVHLGIAGPASPASLAKYALQCGVSLSGKMMLNNRNARKLL
TQWNPSALLEDLMRFYPVSRPSAIHIFPFGGISKTSEWIKKMTLFPEAKPVY
>A0A351SDV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNPLETASESKKIKFSFEFFPPANAKIERMMWRSMGQFMLLDPEFVSVTYGAGGSTQEKS
IQIVEQMQVETSVPTAAHLTCVGASKSEVNAVAQKFWDLGISRIVALRGDPQGETQAFTA
HPDGYTCAAELVEGLRQLADFDISVAAYPEMHPEAQSPQADIDYLKRKLDAGANRAITQY
FFDTETYEVFLNKCIQSGIEKDIVPGIMPIHNFKKIVNFSQRCGAGIPWQYEQDFERHEH
DPVGYRQLSIDLAVEQCRQLQDIGVMHFHFYTLNRSDLCYEIAKALLI
>A0A523KQR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIQRLSFEFFPANTEQGRRSLERTRGRLTAYAPEFYSVTYGAGGSTRDRTFDAVAAIAAD
AMPVAPHLSIGNDDHDTLRKLLDRYRDLGINRIVALRGDVPSGMGSRRNVRYAAELVELI
RSHSGNAFHIEVAAYPEAHPDAPSPDADLDFFHAKVSAGANSAITQYFFNADAYFDFVDR
CRARGIDVPIVPGIMPITNFANLVKFSDNCGAEIPRWIRLRLESHQDDPESLTQFGTEVV
TDLCRRLLAGGAPGLHFYTLNRARPSQAVLDNLAD
>A0A2D8XZL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MXADPTVSFEFFPPRDXIGEQKLINEVLPHLXLFNPXFVSVTYGAGGSTKEGTFSAIRKL
XGKKLDPIPHXSVGNDSDHEIVKVIHSYRELGVTNILALRGDVPSGYGAGQIKNAAYLVR
LIRKEFGDDLGILVAAYPEIHPESETLDIDLSFFKEKVEAGADSAITQFFXNPDAXDNFL
NXIDKNNIRIPIVPGXMPIQNVDGLLRMSKQCKAEIPRWLEYSLXDXXEDLQKFAIELVT
RLCDRXIXLGAPGLHFYTLNRWGAVSRICKNLNLQRE
>A0A432EID4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTDTTSTSFLTPHPSLSFEFFPPKTDKGRENLKKTLTELGKLGPEYFSVTYGAGGSTREG
TVETIRTILDAGFEAAPHIACIGSSREEIRSLLDEYKAMGVKRVVALRGDLPSGMGVGQY
GDFQFATELVRFIREESGDVFKIEVAAYPEFHPQSPTAREDLLHFREKVEAGADEAITQY
FYNADAYVHFVESVRKMGVETPIVPGIMPISNFQQLSRFSAACGAEIPRWLRKRMEGYGD
EVEKMQASATDVVARLSRQLLDAGAPGLHFYTMNKVEPTREICQRLGW
>A0A1H7EF43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. OK202|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAARQQLYVRKPQFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFLYASDLVAFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSAEAYFRFVDD
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TELCARLQEGGAPALHFYTMNQSAATLAVLERLD
>A0A542DE89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis cihanbeyliensis|TrEMBL
MNTNDALQRSLAGARFEVLPLRGAAERVEHLPAGTTVTVTSSPAKGMTATLELAERLRGA
GYHAVPHLAARSILDPAHLKDLLDRMADTGLSEAFVIAGDSPTPAGEFTDSLGLLRAMAE
LGRRPARIGVGGYPERHAFIPDADVTAALAAKAAHADYLVSQICFDSVVTASWVQDLRAR
GIELPIHLGIPGVVDGTKLMRISMKIGIGESLRFLRKQHGMVGKLLTRYTPEGLCRELAP
VVADPAYGIAGWHFFTFNEIARTRRFRDELSVRLQEVPA
>A0A534AMD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPILPGHTSPGRFERVLRAGQFAVTSELAPPDSADPEDVYRRARIFDG
HVDAINATDGSGANCHMSSLAVCALLTRMGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQALPVFDLDSVSLLETARTLRDEHRFLSGRKISYAPRLLLGAAE
NPFAKPCEWRAQRLAKKVAAGAQFIQTQFCYDVPLLRAFMRQVEELGLLDKVFILVGVGP
LRSVKAAEWIRTHVPGVHIPDAIIKRLAGASDGALEGRKLCIDLIQEIRTVKGVHGVHIM
AYRQEETVAEIIERSGVLGGRVPWYPGRDPQASTNRMAS
>A0A359BEH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
KHPFELFVAAYPETHPQAISADNDLENLKRKADAGSRHAITQFFFDNEIFLRFRDRVAAA
QINVELIPGILPVTNFNTLTRFAGACGASIPQWFSTQFEGLDEDPATRQLIAAHAAVSQA
EHLGREGVDVFHFYTLNRADLSFAVCHALGVRGRA
>A0A523L0Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTAQTLRIVLKLCELTGQDTVYALPMIFADKLKTQFVVTSELTPPKGTNLDGLLSTASAL
RECVDAINVTDSHSARMSMSPLAAAHLLIDEGIEPILQLVTRDRNRIALQSDMLGAFALG
IRNLVCMGGDSPAVGDHPDAKPVFDLATTELIGAARCLNKGMDLGGCELKTPTNFCIGAV
VNPGASDLAMEISRMEEKVAAGASFFQTQAVYDITAFEDFLAGVRHLNVAIIAGVMPIKS
VKMALYANEKIPGITIPEDLIRQIDQADDVAATSIRLAAETVAALRGVCAGVHLMTLGAE
QRIPYILESAGL
>A0A534H9H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNAESGRTPIRVSFEFFPPADEAMGAMLWKSIERLAPLAPRFVSVTYGADGSTRERTHNV
VTRIQRETPLTGAPHLTCIGASREEILEIARGYWDEGIRHMVALRGDPPQGEGARRPNPR
GFRYASELVAALAALAPFDISVAAYPEVHPEARSAAADLENLKRKIDAGATRAITQFFFD
TDAFLRFRDALAAAGVHAPIVPGILPITRFPQVLRFAKACGTSIPGRLHERFAGLDDDHE
TRRMIAASVAIEQVEALRRHGVSEFHFYTLNRAELTYAICHALGLRPHARSASAALQEAR
A
>A0A356K688|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSQPQISYEFFPPHTKAGITKLVETAQVLAATDPAYFSVTYGAGGSTRTRTYETVVKLME
SGMTMAPHLSWGSDSESTVVSLLDKYRELGVTRIVALRGDPPSGIGSITPIRRAHSLVDL
IRRRFGDTFIIHVAAYPETHPDALSPEDDIRFLRKKIEAGASDCITQYFFNADSYFYFID
RCQAHGIETPIVPGIMPITNYEGLVRFSDGCGADIPRWIRTRLAHLVDKPEDLLAFGIEV
VTNLCERLLNGGAPGIHFYTLNKPVASAQIARNLGLG
>A0A2E1N4K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
APHLSIGGSSDAALAQLVDYYQEIGVTKILCLRSDQPSGDASKPAXAKDLVERLQQXFPK
QFELAVAAYPEVHPDASSAXDDXAHFVAKVNAGASSAITQYFYNPEAYGYFLDRCAKAGV
SIPITPGIMPITNINALQRFSAKAGADIPRWLAKSMSSYASDDKGLVDFGVEVXXKLCER
XLELGAPGLHFYTLNRWGASSQLCRNLGFLERXFVTLK
>A0A3C1PSF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGAPRVSFEFFPPKTLEAEASLWKTVNRLKALRPEFVSVTYGADGSTRERTHQVIKDILT
KTSLRPAPHLTCVGTPQKEIDAIADEYWSMGVRQIVALRGDPEGGAEANYIPHPEGYAYA
SDLVQGLLEKHPFELLVAAYPETHPQAISADKDLENLKRKIDAGSRRAITQFFFDNEMFL
RFRDRVAAAQMNVKLIPGILPVTNFNTLTRFAGACGASIPQWFSTQFEGLDEDPTTRQLI
AAHAAVSQAEQLGREGVDDFHFYTLNRADLSFAVCHALGVRGRA
>A0A2D6JKH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionaceae bacterium|TrEMBL
MKVTDILKKNEFSASFEFFPPKTSESSEALFNNIKDLLPLGPSFVSVTYGAGGTTQELTK
NLVLKLRKDTNLCIVSHLTCVGHSQEEIHQLLENYNSADIKNLMVLRGDPPKGQNKFVAH
DGGFEYAADLLGYIKKHFPDFDCGVAAYPEGHPETPNRLKEMDYLKAKVDQGADYICTQL
FFDNNAFYDFCERCEIAGIKIPIVAGIMPISSLKGLKRMADLSGGSNFPAPLLRALNRAD
SEDGVSRVGIHWASEQVRDLVDNKVKGVHFYTLNQSKATVEIYKNLGIKNSGSLKKPSFF
SL
>A0A357KNB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MESQRKHPQTFSFELFPPRTEKGIESLRGHRDQLAKLNPKFFSVTFGAGGSTQERTLDTV
LEIQQASGIDAAPHLSCVGSSRERISSILNTYKDAGIRHIVALRGDLPSGVREPGEFRYA
NELVSYIREETGDHFYIEVAAYPETHPQAGNAVKDLENFKNKMNAGANTAITQYFFNPDS
YFAFIDSCEKMGIDAPIVPGIMPINNYIQLARFSDACGAEIPRWIRQRLESYGDDLDSIK
HFGVEVITKMCDRLLSEGAPGLHFYTMNKAEPTVTIWNNLGLSENN
>A0A7X2PLM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacterales bacterium|TrEMBL
MPSRAKEFRQHLAGRVLVADGAMGTMLYSRGVFINRCYDELNLSSPDMVKTIHREYADAG
AEILETNTFGASRLRLAGFGLTEKLNAINEAGVKLAREAAGRTGAFVAGAMGPIGSHLEP
LGSVSFEEARDIFREQIEALLEGGVDLVVLETFNNLDELRIAVEATRAAAGEEMVIVAQV
TIDDEGRIRGGLDTEAFTRELDQWPLDVIGANCSVGPKVMLETVEKIVQFTRKPVSAMPN
AGHPSRVEGRSIYLCSPEYMSQYARRLLWAGAKIVGGCCGTTPEHIKLIRSEARSLQPGQ
RELKVTVSEPKAKAQAMEKIPVALKSGLGAKLAAGKFVAFVEILPPRGVDASKEIAGARL
CAAAGIDCINVPDGPRASARLSAQITCQLIQRDAGIEAVNHFCCRDRNILGIQSELLGAH
AAGIRNLICITGDPPRMGTYPDATAVFDVDAIGLVHIVDNLNHGLDIGGAPIGSQTSLLI
GVGANPGAMNMAEELHRFERKIEGGAEYVVTQPVFDLDLLEAFLKNTERFKVPVIAGIWP
LTSYRNAEFMVNELRVPVPERFMERMRGVDNADKAREEGVAIAREMVERVRHMVQGVQLS
APFGRYQMAIDVAEAIGPR
>A0A7Z8VHE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium CS5|TrEMBL
MTIKNKADLFSFEFYPPKTEQGDLNLEQVHRDLAKLNPDFFSVTFGAGGSTRDKTYDTVV
KIQKNGVSAAPHLSCVASTKENIREILANYREHGVSKIVALRGDLPSGMMSAGEFRFANE
LVDFIRAETGDHFQIHVAGYPEVHPQAGNATEDFNNFKRKVDAGADAVITQYFYNAEAYF
YFLDKCEKSGINIPIVPGIMPITNYAQLFRFSDMCGADIPRWMRKTLECFGDDKASIMAF
GEDVVSKLCQELLDNGAPGLHFYTMNQSKPTLAVWDNLSFA
>A0A1G0L8D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium GWC2_71_9|TrEMBL
MRNLRALIDDGRVHVLDGAMGTMLYGKGVFINVCYDEVNLRSPELVRDVHRAYLKAGAEI
LETNTFGANPVKLGHYLLAEQTVEINRRAAQIAVEAADGRASVVGAIGPLGVRLEPFGET
GRDEAFAFFRQQAEGLTAGGVDGFILETFSDLDELHEALRAVRATSGLPAFAQVTITEDG
ATFYGTDVETVARALDEWGADVIGVNCSVGPQGVLEAIERMARVTGRPLSALPNAGLPRE
IGDRKIYMASPEYFGTYAKTLVEAGARFVGGCCGTTPEHIKEMVAFVASVSPRRVVPVSA
GPVIPPAGVEPVPLAARSAWGRRLAAGEFVTTVEIVPPRGTEPEKMLESVRMLKAAGVHA
VNVPDGPRAQSRMGALMTALLIEREVGLETVIHYCCRDRNLLSMLSDLLGAAAHGLHNLL
LITGDPPKMGPYPEATAVFDIDAIGLTNLVYRLNHGLDPGGNAIGKPTAFVIGVGVNPAA
VDLDRELKRFAWKVDAGAEYAITQPVFDPAQLERFLARVEGYRIPIVAGIWPLVSLRNAE
FLANEVPGVSVPPDVIERMRRVQELGKEAAVAEGVAIAREMLQRVRPMVQGVQVSAPFGR
VPVALEVFQGV
>A0A1F6CD76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Handelsmanbacteria sp. (strain RIFCSPLOWO2_12_FULL_64_10)|TrEMBL
MDLSFREALTETDDFVFCVELVTSRGVIIEKHGKKVLELARRLVEWDHIHALSITDNPGG
NAMLSPDTLGTDLISRGQEIIIHLSCKDWNRNALQSRAWELASAGFHNILTLSGDYPTGG
YRGQAAPVFDIDSVGLLEMLSDMNRGLKVQGLRPGSVERLSRTQFFLGAVVSPFKLQERE
LIPQYLKLARKVESGAAFIITQLGYDSRKFDELLRYVALKGLKVPAIANVYVLNLAAARY
FHRGDMPGCVVTSDLLRLVERQAASPDRGKGFFLELAARQVAVARGLGYRGAYLGGHLAF
EDYRKVLETEASFGPDDWRTFAKEIAFSQRGEFYCFDPDPETGLNTPQVSRAYLASKEEE
ALRRARMDLPLSYRLNRRIHNGVFEKGSLGFKLGQEVYQRIESAGERTKVVAHAVEHAVK
AVAFDCRDCGDCSLPDIAYLCPESQCAKNQRNGPCGGTRQGKCEVGEKECIWALAYDRLK
AYGEEEAMLQRPVVFRDAALRGTSAWANTFLGRDHHAKQSETANGKRQT
>A0A066TGB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snodgrassella alvi|TrEMBL
MSFTSLSFEFFPPRTEEGRRKLAITRKQLSQYQPEYFSCTYGAGGTTRAGTLQTITDILN
DGVAAAPHLACIGASREEMISLLQTYKDMGIHHIVALRGDIPSGVGFGHQGLRYANELVG
LIRQEFGDWFHIEIAAYPEFHPQSRSAEDDINHFVRKCQAGADSAITQYFFNADSYFWFV
DEVQSRGVNIPIIPGIMPIASFSKLARFSETCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEICDNLLQQGAPGLHFYTLNQAGLVSTICQRLGY
>A0A673GDN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus rhinocerous|TrEMBL
MIIYADGRNLQKDKHHCNTPSSFTLSFWGIVCKIEENNKFDPFWNKAVCNMTKCGKSEAF
DRMGSGGPLFIDVTWHPAGDPGSDKETSSMIITSTAVNYCGLESVLHLTCCNQTQEKITA
HLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLVKHIRCEFDDYFDICVAGYPTG
HPEAESYEDDLRHLKEKVDAGAHFIVTQLFFRAETFLKFVKDCRAIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRSYGIQQAVEMCKVLLASGEVPGLHF
YTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIHRTQD
WDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYIT
AQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSSDPIVGW
GPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVQGRNTTNAHDMQPNAVT
WGIFPGREIIQPTVVDPVSFMYWKVMLFPLSNHL
>D2BR22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis (strain KF147)|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>B5Y6J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprothermobacter proteolyticus (strain ATCC 35245 / DSM 5265 / OCM 4 / BT)|TrEMBL
MKVTDKIKQGRIISIEVLPPNRGHSAEDIFKAVDELITDYPISFINVTRHAAETTYVELE
DGIIVKVPKVKRPGTVGLTAALMKRYSVDVVPHVLCRGMNKFELEDLLIDLYLIGVQNVF
AIRGEYENAEGESKQENNKDYHTYAVDLVQQIAHMNKGHYLYQKESTMSTDFCIGVAGYP
EKHFEAPNLEEDMKHLKEKVEAGANYIITQMVFDFDVYKDFVERARSIGINVPIIPGIKP
VVSLKSIYSIPRKFFVNIPHAFLEKMQEAKSSKEEFEVGTAFMASLVEKLLSWGAPGLHL
FTMGKSKSAKALLQAVWR
>A0A2L0GJ02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyrobacter sp. HT-58-2|TrEMBL
MTPTLDQLHEYRTATDTPLFSGLPGDVAVSFEFFPPKSEKMEAQLWDAVTQLKPLGPSFV
SVTYGAGGSTRERTHATVARIIAEGKLPAAAHLTCVAASKAEIREVAEHYWEAGVRHIVA
LRGDAGEPGAPFTPHPEGYASAAELVAGLKAIAPFEISVAAYPETHPDAASPAADIDNLK
RKLDAGATRAISQFFFSAETFFRFRDACAAAGIDAPILPGILPVTNVAQARKFAAACGAA
IPAWMDGLFEGLDEKPAARQLVAATVAAELCRRLYAGGVRDFHFYTLNRPELAYAICHLL
GKRPTGEAA
>A0A2T5JL58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira sp. Nsp5|TrEMBL
MESQKKFAPTFSFEFFPPQTREGIEKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETV
LEIQAEGYAAAPHLSCIGSTRENIRTMLQKYRDGGIRHIVALRGDLPSGMAQWGEFRYAD
ELVSFIRKEFGNAFHIEVASYPECHPQADSAQDDLLNFKRKVEAGADSVITQYFYNADAY
FNFIEACEEMGIGVPIVPGIMPINKFSQLARFSDSCGAEIPRWIRKKLEGYGDDSASIRA
FGLDVVTDLCDRLLSAGAPGLHFYTLNSAGLTTTIWQRLGL
>A0A2N9XBD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snodgrassella alvi|TrEMBL
MSFTSLSFEFFPPRTEEGRRKLAITRKQLSQYQPEYFSCTYGAGGTTRAGTLQTITDILN
DGVAAAPHLACIGASRQEMISLLQTYKDMGIRHIVALRGDIPSGVGFGHQGLRYANELVG
LIRQEFGDWFHIEIAAYPEFHPQSRSAEDDINHFVRKCQAGADSAITQYFFNADSYFWFV
DEVQSRGVNIPIIPGIMPIASFSKLARFSETCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEICDNLLQQGAPSLHFYTLNQAGLVSTICQRLGY
>A0A3D1AX10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacterales bacterium|TrEMBL
RELTIDIVSRIKTETGIEAMAHLTCVGSTRADLESVLDRLTAAGIENVLALRGDPPKGQA
TFTAVEGGFAYADDLVRMIRSARGPGVSVGAAAYPEKHPECANPAVDLANLKRKVDAGVD
FLVTQLFFDNRRYFEFVERARACGIQVPIIPGIMPITNAGQVERFTAACGASLPFALAAE
LDRRRHDAAAVQQLGVAHATAQCIELLTSGAPGIHFYTLNRSTATRNVFLALQSIGFM
>A0A7K4TQR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinosuthora webbiana|TrEMBL
MVNETQQTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDSDRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLERVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>J4UI04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoanaerobaculum sp. ICM7|TrEMBL
MENIRDYLKNNILLFDGAMGTYYDELTDDGIGCELANIKNPELIKGIHNEYIEAGAKAIL
TNTFSTGIDAFLGDRDLQKKVILSGIDIALEVAKDRAYVFADMASINADSNSAAFEEYKI
IADIFLEKGINNFYFETRNSSIGLKSIGEYIKEKSPEAFIIASFAVMPDGYSSEGYYYKT
MFKEICESGFFDGVGLNCVSGANHMAKLLKDVDTEGLYLAAMPNAGYPIVRDNKIYYGSL
ANYFAAQIEDILDMGVNVVGGCCGTTPKHIELLKKSMSGMLIKPRKSVKKEKNVSQNVRL
NRFEQKLISGQKPIAVELDSPIDTNVSKFIDNAAKLKSAGADIVTIADNPIARARMDSCL
LACKVRNELDFDVLPHMTCRDRNVNAAKGLLLGASAMGVDNVLVITGDPIPNAQRDEIRS
VFEFNSVKFANFINSLNDEVFESPMNICGALNVNSKNFSAELRKAKRKQENGVKVLFTQP
VLTKRAIDNLKEARENLDVKIMGGIIPIVSERNARYMQSEVNGIYITDDIVEKYIGKERE
EAEEIALSMSKEIANEIYDLVDGYYLITVLNRVNLMERLIKTVKEVCENR
>A0A2T2T489|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QH_6_63_17|TrEMBL
MKVTEHFDQASEPLISYEIIPPKRGGSAEQMLEVVEELMPFDPPFIDVTSHSAEVEYKQK
DDGTWERCVKRKRPGTIGLCAAIEARFGIDTVPHLLCKGFTCEETEDALIELNYLGIDNV
LAIRGDDKGYEKSISENRSRNEYAVDLVQQIQDMNQGAYLEDLMNAEPTDFCVGVGGYPE
THFEAPNLAWDIMRLKEKVDAGADYVVTQMFFDNEYFFRFVDKCREVGIDVPIVPGIKIM
KRKRHLRTLPKYFHTEIPEELAAEIDAAGPEDMEKIGVDWAIRQAHELMEADVPCIHFYI
MSSADTVKKVVEPLREPKEVA
>A0A505H261|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. XM4083|TrEMBL
MSVSALRTLLKSARYEVLPTAGIVDRISDHVAPGRTITVTASTGMGLEATLSTAEALQAR
GYTAVPHIAARMVQGRTELEEIIDRLGRAGIATIFVPAGDATPPAGGYASALDLLVDLTS
LAPPITQIGVAAYPESHPLIPDDVTVQAMWDKRDYATHIVSNLCFDPGIVSTWLARVRAR
GIEMPLILGIAGKVELAKLAKVATKIGVGESTRFLRKNTATFTRMAKPGGYNPRRFLDRL
SPVLADPYMGVSGLHIYTFNQVKDTEAWRRRQLELLGDPDPASVTS
>A0A0M3QDW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. (strain 113P3)|TrEMBL
MISTLNSAAEARRAAASPLFADLAGDISVSFEFFPPKTEKMEAQLWDTFHTLEPLCPSFV
SVTYGAGGSTRERTHATVARIAAKSRVPPAAHLTCVEASREEIDAVARAYWEAGVRHIVA
LRGDVPGGEPYRAHPQGYANAAELVAGLKAIAPFDISVAAYPEVHPDADCPQADLDNLKR
KLDAGATRAITQFFFSPDAFLRFRDTAAAAGIDAPIIPGILPVSNVSQTRRMADMCGAAI
PPWMVSLFDGLDDLPAARQLIAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPAAQPIKEQAA
>A0A225B6Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces atroroseus|TrEMBL
MEKITEKIAALPPDERYFSLEFFPPKTQMGSVNLQARLERMAQALRPLFVTVTWGAGGTT
AAKSLELAEICQRQLQLTTCLHLTCTNMNRKLIDEALEEAKALGIRNILALRGDPPRSEE
YNMDGDDDSNKDFTWAIDLVRYIRRTHGDYFCLGVAAYPEGHPGESQTDIQDPEKDLPYL
VDKVQAGADFIMTQLTYDFDAYKKFEESVRNHPSGAMKNIPIIPGLMPIHGYKILTRVTK
LSGAHIPPAIMSRLEQVKTDDEQVKQVGVDIVSEIVDQIKELPRSGHRGYHFYTLNLEKS
VSFILERCDLIPQFSQDSAVDEDIAVEDAASSNNIDGVKPTALSRRRASSINSGPHNRVI
VDKLHVPTDQQSERSSKRSITYETLASSAGVPALNPPPRSTQLQISEGVGSLGREATWDD
FPNGRWGDSRSPAFGEIDGYGPSLHVNATTARQLWGFPVTRDDIGALFRKHVAGELYIVP
WSEGGAAEDANLNAETQVIKSQLLQIIEKKNWWTLASQPAVNGVRSDDPIFGWGPPGEGF
VFQKAFVEFFCPSSDYQTKVKPTLLKHGSEEFAWFATNAAGDFESSFSAVAASSSSSPPS
SSPGASAADDEQVEISENTGMAVTWGAFRGREITTPTIIEGVSFHAWGEEAFRIWDEWRR
IYPRGSATERLLNETKNDVWLVCVIGHRYGAGNEPGSEAEKKEMNMLWDVLAGDM
>A0A6B2FDI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. MIT 19-121|TrEMBL
MNAKASFSFEIFPPRKSDSIDKIYTTLEQLKDLKPDFISVTFGAGGSINSQNTLDIASLV
QDRYKTSSIVHLPCIHQNKAQISSILNECKKRGLQKILALRGDIVEGKEKSVDFAYASDL
VRFIKEQGDFEIYAACYPEKHNEALNFTEDIHHLKEKVDAGANTLLTQLFFDNEDFYRFK
EYCDIANIKAEIKAGIMPIANKRQVLKITSMCGSKIPAKFAKILHKYEHNDKAMIDAGIA
YAIDQIVDLLTNGVSGIHLYTMNNAYVAKKVFEATHSLFEA
>A0A315W9T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gambusia affinis|TrEMBL
MVNQVQQVDGSWLSCRGDSSGASNSSAESSKESSRCSTPLLDADRSDRLREKMRKRIDSG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGDDWEDEEGGFNFAV
DLVKHIRSEFDEYFDICVAGYPTGHPEAESYEQDLQHLKEKVDAGADFVITQLFFRPDTF
LKFLDDCRAVGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIHQAVDMCRVLLDSGKVPGLHFYTLNREVAPMEVLRQLGLWVEDPRRPLPWAVSANPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKNEQSVFEVFTCYITAQPNRNGQKVLCLPWNDEPLAPETNFLKDELEKVNR
RGVLTINSQPNINGKPSADPVVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVDVHGHNMTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIVKYIHDNYFLVNLVDNDFPLDSCLWRVIDDMFELLDATPEPPSDEAGL
>A0A285T660|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter maris|TrEMBL
MPTPKISFEFFPPQTLDASFRLWETAQVLAPLKPNFVSVTYGAGGTTRKLTHDAVETIHK
NYGLNVAAHLTCVNATRAETQEIIDAYAEAGVTEIVALRGDPPKGENKFTPHPEGFASSV
ELIEFLAADGRFKLHCGAYPEAHPEAADTLADVRWLKRKVEAGATSAITQFFFEAETFFR
FRDACVKEGIEAKIIPGILPIQSWKGAKSFAQRCGTSIPAWVEDAFDHALRDDRESLLAT
ALCTELCDNLIAGGVEDLHFYTLNRPQMTRDVCHALGVTPDVVLENVA
>A0A410GDZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas thiosulfatoxidans|TrEMBL
MTTQQAISLEFFPPRDIAAQERLVRSAKQLLALHPAYVSVTFGAGGSTRSGTAETVKLMQ
NLGCDAAPHLSCIGASRATLGEILDAYRAQGIKRIVALRGDMPSGMGGDAGELHYASELV
AFIRQHSGDAFHIEVAAYPEMHPQASSAQADLDHFVAKVQAGADSAITQYFFNADAYFDF
VERVQARGINVPVVPGIMPITNYAQLSRFSNMCGAEIPRWIRLRLADFGDDKASIKAFGI
DVIGKLSQDLLDKGAPGLHFYTLNNADVTMAIWRQLSLDA
>A0A505H0T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. XM4083|TrEMBL
MSTSLTHPDPVLDSSFRDVDRRPPIDHRPPRPHPDADATVREPRASASAPVSLPHPEPDS
ERHHPLALSFEVMPPRSAAQAAGTPELLALLDELHPDYLAVTSSAKSNWLHGTADFIRII
SETTQLRPLAHLACTAGTADELRGWIRHLLSAGVRGFLAIRGDFPTGTDRVPAGHLPHAD
ALVHLLRTIEAEHTAKLAAGRLGIGVAAYPSGHAQSSGPDEDLDVLAAKQRLGADFAITQ
LFFDPGHFARLRRRADLAGITMPIIPGILPITDIRRLHTMSRLAELPVPDHLLARFDGAA
SPQAQRRIGLEMTAEHVATILDQGAAGLHFYTFNDRTTTIDLLGALDRLGVSLHPTPVPA
L
>A0A329KZ75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. YN15|TrEMBL
MNKNKEQPSMSHKLAEQIMNRRTGILTYGMTPPKLGTPEEKLITIAGTQHQRIASLPIDG
LILYDVQEEDSREGDRPFPYLEALDPGFYRSTYLGGLQTPSILYRSVGKYRPDELEAWAA
RQPQGACAVFVGASSSAQPVKTTLPHAFEIGRRYPQLLMGGVMIPERHMNTRDEHMRVIR
KMESGCRFFVSQAIYNVEASKDFLSDYYYACQEQELEMVPILFNFAPCGSLKTLEFIKWL
GISLPRWLEQDLIHSHDILDKSITLVRKIMDELMDFALEKGIPVGCSVESVSTRKVEIEA
SLQLLWDIRGDMDKKLGCV
>A0A2G2QMQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cycloclasticus sp|TrEMBL
MALESHQPISFEFFPPKTEEGRVKLLNVSKKLGQLDPAYFSVTFGAGGSTQQGTIDTVLD
IKKQGFSAAPHLSCVGSTKENIRAILANYKENGVDRIVALRGDIPSGTLDIGEFRYANEL
VGFIREETGDHFHIEVAAYPEIHPQAKNAQTDLKNFKQKVDAGANGAITQYFFNFEAYIR
FVEDCDKMGINVPIVPGIMPITNYSQLARFSDMCGAEIPRWIAKRLEGFGDDRESIKAFG
ADVVSELCQSLLDYGCPGLHFYSMNQAEASLAICCNLGVENA
>A0A1F4Q3I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division NC10 bacterium RIFCSPLOWO2_02_FULL_66_22|TrEMBL
MKFRDAYGSGKFGLSFEIFPPKMPAGEGALLEAIEALMAFRPSFVTCTYGAGGSTREKTL
ELTVAIRERFGVSTAAHLTCVGSSYEALRAWLAVAASQRIENIVALRGDPPRGESRFIPA
DGGPAHATELVAFIRREFPQFGVGVAGYPETHQEAVSPEADLAHLKRKVEAGADAVITQL
FYDNRDFFAFRRRYEQAGIRVPLVPGILAIINFAQVQRITTLCGAKLPPALVAQLEDRRD
DAEAELKIGVAHAIRQCRELLDAGVPGLHFYVLNKATAPARILEALDLPARAAGRV
>A0A7W8XZ70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MPDISTASIIPASIEASPAQVLGSTDLAGLFPQGVRVYLTDTGAASQERVVEAAGHLRDL
GYEPVPHLAARRIPSRAAFEEQVKRLAGEAGVTDVLVVGGGVDRPAGSFASSMDMLSTGI
FDRCGIRQIAIAGHPEGSPDFNDETAMAALRLKRDFAERSDAAMRIVTQFGFDPARFIAW
AEGLAASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTTLAKGHSPES
IVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGAVDRSASPDSMAG
>A0A8H3F4N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alectoria fallacina|TrEMBL
MHIKDKLAEAERTRKPVFSFEFFPPKTALGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRS
DLTCEMVNTAQTIYGLETCMHLTCTDMEKQKVDDALKSAYSAGCSNILALRGDPPRENEK
WQAVEGGFRYARDLVEYIKARYGNHFDIGVAGYPEGCDDQQDQEILMEHLKEKVDAGGTF
IVTQMFYDVDIFLSWVKKVRACGITVPIVPGIMPIQTHAAFLRRAIWSKCHIPQKWADAL
EPIKNDDAQVREVGKGLVTEMCRRIIDAGILQLHFYTMNLAQATRMILEELDLVPKDGTP
NNRSLPWRQSLGLNRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDARSPAFGELDA
YDIGLKGTNEQNVKLWGKPESIRDVADIFIRFLEGKLQSLPWSEAPITSEAEAIRPELVN
LNRRGLLTITSQPSVNGVKSTHPVYGWGPKGGYVYQKAYIELLISPQLIPELVARIERNP
NMTYYAVTKDGDLRTNAPSEGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAYHLGIDW
AKCYPASSPSRQLIDKIMDTWYLINIVDNDFHQTHAIFSLFQGLEAENLEKSLAVDKPAV
NGHQSNDVQGPVANGAARKVHS
>A0A1I7JPU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas korlensis|TrEMBL
MTTARFELLPIAGLQEAARALPHGAVVTVTCSPRHGLERTLAASEWLVGRGFHVVPHLAA
RLMRDRAHLEQLLGRLAALGIDEAFVVGGDVERAVGDYPHGLALLEALDGLELRPARIGV
PVYPEGHHRIEAAQLQRDLEAKVALADYAVTQLCFEAAPLLAWRERQRRLGLSLPVHAGI
PGVMEPRRLLTIALRLGLGPSVRTLRRQSGWMARLLRPSPYRPDALLEGVGPLLGDAQAG
FVGLHVYTFNRVESTRHWLEKRLELVPGRPALDQPEDQAATPAGGPLA
>A0A845YX91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO3B3|TrEMBL
MNRFRNAVKSGEFLVTAEVAPPKGGDPTHMIEMLEGLKGRVHAVNVTDGSRAVLRMSSLA
ASIILKNNGIEPICQVACRDRNRIGLQADLMGASALGLHNILALTGDPVKAGDHKDARSV
FDMESVRLLQMIAKLNQGIDWNEKALPDGATDLFAGAAVDPQSPSWSGLKKRFERKLLAG
CQFFQSQLISDFDKLEKFMNQIAVESNKPILAGIFLLKSAKNAAFINKYVPGVDIPEHII
NRLAKAEKPLEEGMKIAAEQVQIASKICHGVHLMAIKREDLIPRILDMAEISPIGE
>A9BTP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia acidovorans (strain DSM 14801 / SPH-1)|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A7W9D7U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNPEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLATAAHLTCVDASREDVHQVIDEFRNAGVRHFVALRGDPSTGIGTAYK
PHPEGYENAAALVKGLREIADFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDSVLENLGLERLRRSAA
>A0A845C6L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Holophagales bacterium|TrEMBL
MRRSVAPSTNFAGAARGPSWGRWRDGWRRPAWSSRRSEWPRTRRRIRFVVKLIDKLRSAI
AEERPFYSFEYFPPKTEAGIENLYARIERMGRLEPAFVDVTWGAGGSTAELTFELANTIE
NVLGLETMMHLTCTNMPRRRIAAVLDDCRARGIGNILALRGDPPRGRGAWSPIADGFSHA
SDLVRFIREEHGDHFGVCVGGYPEGHPEAPSRERDLDHLAEKVATGADFVITQMFYEPEL
YFRFLEECRERGVDCPIVPGLAPINGYLSFQRITGFGASAPPEIVSEIEARRFHDASVRE
YGQDLLTGICSRLLEGGAPGLHFYTLNLERSVQVILDRLGIVPERIERVLPWRSATAVQR
PREDVRPIFWANRPKSYLARTQDWDEFPNGRWGDAGSPAFGDLGDHHLAFRPIRSDLARE
RWGRELHSIDQVREVFAGFCRGDVDGIPWYDWPLDLESEPLRNALVRLNLAGLLTINSQP
RVTGAPSDDPAVGWGGAGGRVYQKAYLEFFVAPEQVPTLLAALDAGPSLTYHAIDRSGTA
HSNCDTVNAVTWGVYPGEEIRQPTLVDPRSFEVWKDEAFDLWLSSWAAVYDEGSESRRLL
QRIHDTYFLVNVVDNDYVDGDLLGYLLDAVQADEPPSMTIVAPVT
>A0A1I4SFW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora antimicrobica|TrEMBL
MTKVIDRLRPGKTVFSVEFFPPKTDEEERQLWRAIRELEPLDPAYVSVTYGAGGSSRDRT
VRTTGRIARDTTLVPVAHLTGVNHSIAELRHVIGSYAAEGITNVLAIRGDPPGDPLGEWI
PHPEGITYADELVRLVRECGDFSVGVAAFPHLHPRSPDLESDTEHMVNKLRAGADFSVAQ
MFLEPEYFLRLRDRLEQRGCHQPLLPGVMPITTPKVLGMTTQLSNMTIPDEVSAVLDPLR
EDAPGFREAGLEITTRLCEKLIAEGVPALHFYSLNRAKATREVLANLGLIDGVLKAA
>A0A358RB67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp|TrEMBL
MNVVDIINEAIASKRTRFAFELLPPLKGDGMQKIFAAIDPLMPFDPAYINITFHREGIKE
TERPDGGIEWHVVRRRPGTVGISAAIQHRYGVEVVPHLICGGLSKYDIEDTLIDMDFLGL
HNVLALRGDKSQNERRFMPHPQGHAHAVDLVRQIAAMNRGEFVDGEVEECHHSKFSIGVA
GYPEVHFEARDITTDILHLKEKIDAGAEYVVTQMFFDNRKYFDFVRRCREAGIRVPIIPG
IKPISTLRHLEVLPETFGVELPGELVREARAHPDNVREVGIEWTVAQSRELMAAGVPVLH
YYTMSRTNNIQQIVRTLF
>A0A4Z1QYI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MIIKRITHKLPDISAASIIPASIEASPAQVLGSTDLAGLFPQGVRVYLTDTGAASQERLV
EAAGHLRDLGYEPVPHLAARRIPSRAAFEEQVKRLAGEAGVTDVLVVGGGVDRPAGTFAS
SMDMLSTGIFDRCGIRQIAIAGHPEGSPDFNDETAMAALRLKRDFAERSDAAMRIVTQFG
FDPARFIAWAEGLAASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESIVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGAVDRSAS
PDSMAG
>A0A2T2R5I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium QS_8_72_14|TrEMBL
MQSTTTDRHAGSASPLRRRRHRPAATSGRRPALRRALAAVTGDIQWEVLPLSGVAEQTSH
LPVGARVTVTCAPARGIDPTVDLAVSLAGRGFVAVPHLAARQIHGHGHLTEVLDRLAAAG
VDEAFVVGGDATEPAGPFTDGLTALEAMASRGHGLSRLGVPAYPEGHDHIDDEILWQSLK
AKQAHADYIVTQMCFDSAAICDWVTAARQRGISVPVYAGVPGVVDPATLLRISRRIGIGD
SLRFLRGNRRVMGSLVRPGGYRPDELLRGLADRVGQGCDLSGLHVYTFNRVAPTVGRIDT
LRRRGLSPQG
>R9MMZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium MD308|TrEMBL
MKIKDILKETTPHISFEVFPPKTDAGFESVLAATDQIAALKPSYISVTYGAGGGTSKNTV
NIASHIKDDLGVTSLAHLTCVSSTRAHVHEVIRQLKEKNIENILALRGDIPKESEFPLPN
QYRYASELIGEIKEQGDFCIGAACYPEGHVETERKKDDIDNLKHKVDCGVDFLTTQMFFE
NSIFYNFLYKIREKGIVIPVLPGIMPVTNKKQMKRICDMSGTVLPQRFIDVLERFGDEPR
AMQQAGIAYATDQIIDLFANGINHVHIYSMNKPEVAEAIMNNLSEIVVRV
>A0A176XE96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MIIKRNMHKLPDNVTTSAIPASIEASPAQVLGATDLSGVFPKGVRVYLTDTGAASQEKLV
QAAAHLHDLGYVPVPHLAARRLPSRAGFEEQVKRLAGEAGVTDVLVVGGGVDRPVGPFAS
SMDLLSTGLLDSCGITQIAIAGHPEGSPDFSDDIAVNALKLKREFAERTNADMRIVTQFG
FDPGRFIAWAEGLALSGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPEGVVGPIERHWRANTQGPIQQIHVFPFGGLQNSADWLVQRGSWKRDPTAHALS
PDSMTG
>A0A1H4R616|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PAN_FS17|TrEMBL
MALGTASIRQDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGDWVRHPQGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAAGCDTPIIPEIMPIASAKTLERIPSLTNAGF
PAALKERILTAKDDPTAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A1L9SML9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicilliopsis zonata CBS 506.65|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGSANLQARLERMAQALRPLFVTVTWGAGGTT
ATRSLELAEICQRQLQLTTCLHLTCTNMSRSLVDEALEQAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFSWAVDLVRYIRKVHGDYFCLGVAAYPEGYANDTFQQVQDPEHDLPYL
VEKVQAGADFIMTQLTYDLEAYEKFERRLRTHESGVFKTIPILPGLMPIHSYKILTRVTK
LSHAHIPPKIMSRIENVKSDDDAVKREGVEILSEMVQGIKKLPNPGRRGFHFYTLNLEKT
VSFILERCDLVPDHDDDDVLEDTSTLGVPTAEQLRSLSRRRASSINSQPHNRVIVDRLQA
STGSSKGSISHEAPATSAGMPALPPNRSTTLQISEGMGSLGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVHATEARRLWGYPVSYADVSALFRRHVSGDLYIVPWSEGGAEEGTGG
LNAETAFIRDDLLKLIDGRGWWTLASQPAVNGVRSDNAMFGWGPPGEGFVFQKPFVEFFC
PRKDFETILKPMFARCGADELAWFATNAAGHFESSSSSASTATATTAARDNATAAADEST
VNTVTWGVFRDKEIVTPTIIEEVSFRAWGEEAYRIWDEWRRVYPRGSATERFLAGLKDDV
WLVCAIGQKYGAGTEAGSAEEQLETSWLWRSLSSA
>A0A421G1F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora kernoviae|TrEMBL
MTFNTLCIHSRRPRMKVIDKINASIERQEVFYSFEFFPPKTPAGVENLYARMDRMAALEP
LFCDMTWGAGGSSAQLTTELSANAQKLSGLEMLMHMTCTNMAAGDIKKALDQAKEAGIQN
ILALRGDPVRGATSFDECDRGFSHAVDLVRYMREEYGDHFCIGVAGYPEGHTESEDKAAD
IKYLKEKVDAGADFIITQLFYDVRVFVEFVKECRAVGITCPIIPGIMPIQNYGGFERMAS
FCNTYVPEEVRKALEPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRR
ILEGLSSLSSRVPRRELPWQTSTLSSRAAESVRPIYWSNRPKSYVHRTAMWDEYPNGRWG
NSESPAFGELAESHFAATNTSTPKERRGMWGEAPATKHDICQTFVQYVRGEISSLPWCDA
ALHAETSTVQHELASANAAGFLTINSQPRVNGALSDDPLFGWGGPGGRVYQKAYVECFVS
PENMKIIIENAAKKSSVQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSF
LVWKDEAFALWLKLWASLYENGSQSAKLLRKIHDTYFLVSIVDNDFVNGNIWDLFEAPTS
STTSP
>A0A556AFB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticiella sediminum|TrEMBL
MTPDSSPAISLEFFPPRDEAAQERMLRAAKQMTALAPRYVSVTFGAGGSTREGTVNAVRT
LRNLGLDAAPHLSCVGATPASLRELLALYRDMGVRRIVALRGDMPSGMGAGVGNLRHASD
LVAFIRQETGDTFHLEVAAYPETHPEAVSPAQDLAHFVEKMKAGADSAITQYFFNPDAYF
DFVERASAQGVSAPIVPGIMPITNYSQLQRFSDMCGAEIPRWVRLRLASFGDDRESIRAF
GQEVVSDLCRRLLAGGAPGLHFYTLNQADATRAICQDLGIGQ
>A0A7K6P8S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ifrita kowaldi|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLRDKMRRRQDAGDK
WFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQAKDDITGHLQKAKRLGLKNIMALRGDPGGEEWEEEVDGFNYAIDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKRYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7L1RTU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Locustella ochotensis|TrEMBL
MVNETQQHICSASSSSRSDGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQSIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A343TL19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halalkaliarchaeum desulfuricum|TrEMBL
MTTNTFKESILDDEEFGVTWEHVPGRGAREQQQDAVFEAAEIASEGDVVDGISVTENAGG
NPAISAEYLGMKLQDLDVDPLVHFTAKDKNRNQLESLLYAMDREGIQNLLVMTGDYQNDG
YQGQSRPVYDLDPVQIMDLISDLNEGLEYTDKFGREKSLEPTDFFAGVAVSPFKRLESEL
VPQYWKLEKKIEQGARFVIPQVGYDARKFHELLQYVEDHDLDVPVIGNIYVLDPGSANAM
NKNRIPGVIVTDDLLEDIETEAEENDDDGKQARLERAAKMYAFMKGMGYDGVHIAGHEVD
HDGVEYVVERGEELVPEWREIVEEFDYPMEDGFYYYERDPETGLNTWERTTLPEQPKQSL
TYRGFKVMHDQLFEPDGALFGPMRWSAKKVDGSRLEEPYQMTERMVKTASNDCQECGNCA
LLDLAYQCPMSQCPKSQRNGPCGGSYDGWCEVHPEEQKCIYVKAYRELKADGGPEKAREK
LRELYIPPPDWELENTSSWLNYFLGRDYASKNAGIEPPTSGD
>A0A1I2PY56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporolactobacillus nakayamae|TrEMBL
MRQSIREELKKRILIGDGAMGTLLYSYGIDRCFEELNVSQAEEVRHVHEAYINAGADVIQ
TNTYGANQVKLARYGLEHEVGRFNRAAVQLAKQAATAETYVFGTIGGIRGFQKQSVEIKE
ICSGFREQADALLNEGADGLLLETYYDFDELREVLQIARKITDLPIIAHVSMQEPGVLLS
GMSLSDALTQLEALGADIVGTNCRLGPFHMIEALRDIPLPKKAFLSAYPNSSLPDYREGK
LHYENEPEYFKKYAVDFRNEGVRLLGGCCGTTPVQIQAFKQGILELEPLESKVVTVQPEV
IKVNKSGANTESPLYEKVLQGRSVFVEFDTPRHLNTAGFFRGVKALEEAGADAITMADNS
LASPRISNAAIGKLIKDRFQIPPLVHLTCRDRNLIGLQSHLLGLHVLGLHDLLIVTGDPT
KIGDFPGATSVYDVSSMELIKLVKQFNRGISYSGKSLKQPTQFRVAAAFNPNVRNLDRAV
QRLERKVECGADYFISQPVFDKERIIEISEAARTITAPIYIGIMPLTSARNAEFLHNEVP
GIRLPDEVRARMAAAQGKEEVRAISLDICRELIDTAMEHFRGIYLITPMGHYSMSVELLK
YIKEKEQELAVQENNAGVIF
>A0A7X9RWV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flammeovirga aprica JL-4|TrEMBL
MKVIDRLNQAAEDKKTLFSFELLPPVRGKSIQSLFDAIDPLMEFNPAFVDVTYHREEYVY
KELSNGLFEKSIQRHRPGTVAVCAAIMHKYKVDTVPHIICGGFSKEETENILIELNFLGI
ENILALRGDAAKGEASFTPHPEGYAYASELVEHVTKMNEGEFKYADQAGFKGGFSIGVAG
YPEKHMDASNMASDIDFLKKKVELGADYIVTQMFFDNQKYFDFVDRCRAAGITVPILPGI
KPLTTQKQLTLLPSIFKLDFPEELLTEAKKCKNNKEIKELGIEWGIKQSKELIEYGVPGM
HFYSMGRSTSVKDIAEAIF
>A0A2C6AF54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cordyceps sp. RAO-2017|TrEMBL
MPGLDDGPATTSGLRIFGAGEGLQSTLDQGFHAADVASSQKITEKIAALPHDADFFSLEF
FPPKTKNGTANLRARIVRMKHALQPLFVSITWGAGGSSFNQSFDLAEKCQRELGLTTLLH
LTTVDMTRQTLDRALARARALGIRNIMALKGDRPRDGSDPAAGHAANDAAVRQDFFWAVD
LVRYIRKAHGNYFNIGVAAYPEGHFNASDPSSRGVEHDLPFLAEKVEAGADFIMTQLFYD
MDAYADFESKVRAYPSEALKKIPIIPGILPIPSQRRFDNTLKLAHATVPDIIRAQLDPVR
KNNTEWMTAGERVVTDLVGAIHERASKRPGPRGYSFFTLNQEEPVSTVLKNTHLASGARK
SGASDA
>A0A7H0SNX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. 4H37-19|TrEMBL
MSTAHLYQDYQPGVPSTHPTVSFELYPPRAQARTSSVWTGINRLIDAAPDYVSVTFGAGG
AKGDSRDRSVQVLMNVLDQRRKLPAVAHLTCLGSTRGDMAMIIRLLLRAGIRDFLALRGD
PPSKDLPLSTEVETMTRAVDLVYLIREIEAEVLDPDRPEDRVSIAVAAYPASSGQARAND
IAALLEKQRAGADYAITQVFYDPAQYDSMVRELTLAGGRLPLIPGIMPLNDLRRLEALER
LSGVPVPQRIVDIHRNPDDSLRVWQSLKATIELIAGVLEAGAPGIHLYTFNRPRPVLDVV
EYLRGGGYLNRYGSTGGTSRMPLPPDVDVELVGLALRRLTPGV
>A0A6J4UQE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Thermomicrobiales bacterium|TrEMBL
MANPLLTRLADGVVLADGALGTMLYAGGAPLDESFDALNLSRPELVAATHRAYLEAGADL
IETNTFGANRYRLEGFGLAEKTLEINKRAVRLAREAREITGRPALVAGSVGPTARTLAPF
GTADPAAVRGVFREQIEALLEGGVDLLIVETIGNLEEMEQAIGAAREASDLPVVAMMTFA
EDGRTIGGSTPEDVVDRLRGLGVTALGANCSVGPQRMLPTVAAMGRRLDELGADGDAPAL
ACMPNAGWPTQVGGRVIYRSSPEYFGDFARRAAEAGVRLIGGCCGTTPAHVRAMREALDA
VASERVAAVDRPEGTSAAAVVTPARPRARPEADLIPAEGPTEICQKLAGGKFLVSVEIDP
PKGLNPAKALEGARLLKEVGVDAINVADSPMARVRMSALTLCYLIQHQVGVETIIHFTTR
DRSLMGLQSELLGAHAVGVRNILALTGDPPSLGDYPDSSAVYDVDSIGLVRVLSRLNGGE
DSAGASIGRPANFTIACAIDPTREDLEEEARRLRAKLEAGANFVMTQPIFDAAVWRRFLD
VYGAERLDVPVLIGILPLQSSRHAEFLHNEVPGITLTDDARDRMRRAGADGRREGVKMAQ
DLLLQLRPEVQGVYLMPSFGRYEVAAEVLRILD
>A0A1H5UK86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp. DSM 26293|TrEMBL
MKRISFEFFPPKTDAGKEKLLATQQKLLAKKPAFFSCTFGAGGSTRDNTRDMVNQLRNQH
GDTAPHLSCIGQSREEILELVNGYKAAGVTRIVALRGDLPSGMGYAQSEIKYADELVQLI
REETGDHFTLEVAAYPEMHPQARSFEDDIAHFKRKVDAGANSGLTQYFYNADAYGYYLDA
LQKIGCDAPVYPGIMPILNVANLVRFSNTCGADIPRWLHSKLNDIKDDDAAVKAFGEEVV
TRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGM
>N8W170|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 102637|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLHIVHQELQRLNPEFFSITYGAGGSTRERTLATIHDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGNHFHIEVAAYPEMHPQADSFDADIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERLEKEGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A4V3KG86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.230.01.1.1|TrEMBL
MNQFRFSRRPDIGEKVRVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVIREFVDFGVTRFVALRGDPAAGVGT
IYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLGNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
AGSAAA
>A0A134AQL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia wadei|TrEMBL
MRIKDLFEKKEHLISFEIFPPNKNFSVEKLKDVTDELVQYKPDFISVTYGAGGKTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEINDYLQEAKKCNIKNILALRGDVPQGETEEIYN
RGDYKYASELISDLRKNSEFNDFSIGGAFYPETHYENNDLVDLFHLKNKVEAGTDFLASQ
MFFDNDIFIKFKEQAEKLDIKVPLIAGIMPVTNAKQIKRIIELSKCSVPEKLDKLLGKYG
DNPESMKKAGIMYASEQIIELLAYGIRGIHIYTMNKPEIAKEIVKNIEFAR
>A0A4Q7TU37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter luti|TrEMBL
MSPALLTGSAPTRARFSFEVFPARSGAAALALGHAVQHLSAAGPDFISVTYGANGSNRDA
SVDLLKYLRDHTDALPLAHLTTVGEDRETVRAAIHSIMDAGVHDFLALRGDPPRGRTEAD
PEVAGSLSALELVELVAEARAERPALTSVGRTSVAAYPNGHPLSRSRSEDIDWLVAKQEA
GAQFAITQLFFRAEEYLSFVSDAQRAGLRIPVLPGLMPVATSGQLRKVAELAGRPAPAEL
TRELDEAGGYAPELGVEHTVELASELLAGGAPSVHLYTFNRHERVLAVLRDLDLLTPDPL
R
>A0A175YPN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Daucus carota subsp. sativus|TrEMBL
MKVIDKIRASQNDVVFSFEFFPPKTEEGVENLFEKMERMVAHNPTFCDITWGAGGSTADL
TLEIANRMQNMVCVETMMHLTCTNMPVDKIDHALDTIKKNGIQNVLALRGDPPHGQDKFV
QVKGGFSCALDLVKHMRSKYGDYFGITVAGYPEAHPDVIQSTGEATLESYKSDMAYLKKK
VDAGADVIVTQLFYDTDIFLKFVNDCREIGITIPIVPGIMPINNYKGFIRMTGFCKTKIP
AEVTDALESIKDNEEAVRAYGIHLGTEMCKKIMATGIKQLHLYTLNMEKSALAILTNLGL
IEESKISRPLPWRRPTNVFRVKENVRPIFWANRPKSYISRTIGWEQYPNGRWGDSCNASY
GAMADHQFMRPRSRDKKLNEEWAVPLKSIEDVYERFNLFCLGKLKSSPWSELDGLQPETK
IINEQLGSINSKGFLTINSQPAVNGAKSDSLSVGWGGPGGYVYQKPYVEFFCSSQKLHAL
VEKCKAFTSLTYMAVDKKGSWVSNIGNSEVNAVTWGVFPSKEIIQPTVVDPSSFLVWKDE
AFELWSKAWAQLYSEEDPSRKLVEEVQNSYFLVSLVDNDYINGDIFAVFKEILKKFSVHG
>A0A3G2R857|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Biomaibacter acetigenes|TrEMBL
MYNNFKSKLKGGQFTVTVEISSPKGTYLNQILQDIRELKDIVDAVNICDNPMANMRMGSI
PLAHIIQETLGIETIPHMACRDRNIIGIQSELLGAWALGIKNIFAVTGDAPAKGDHPGAA
GIFEVDSKGLIKIIDTLNNGKDLANNTLKGSTEFFIGTAANPAAESLDGEIKKLEEKVLS
GANFIQTQPVYDMDVLDRFLEKALLLDVPILVGIMPLKSQRMAINFNSRVEGVNIPLKII
DRMKRGRREGMEISWELAEEIRERGCGVHLMPLGDIEAAVQIIKGLRLPAKKVHDASGTL
>S5SZD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium maris DSM 45190|TrEMBL
MSADVSVRPHRSTRFSASAPLDEDLIPVESQPTKLDPEDLLGRAPGARRRTSLSFEVMPP
RHDSDRSKIDHLLATLESYGPDYLAVTSSQRSDWLTGTSAFIERISQTTRMLPLAHLACT
AGTRDELVGWINRLIDAGVRGFLALRGDYPDGQDGPAPGELPHATDLINLIGEVEGSQAA
RFAAGRLAVGVAAYPSGHYQSSGPDEDIDVLLAKQRLGAGFAITQMFFDPEDYLRFRDRA
RLAGVTIPLIPALAPMISVQRLRRMGQLSGLEVPERLIRRLEKSDTPEGQLDIGMDATAE
MAQTLLSNDTESLHLYTFNRADVTGELLTRIGIAPRHPRA
>A0A1V5LM05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium ADurb.Bin431|TrEMBL
MAKQPFLERVRERILVCDGAMGTMLYSRGIFINRCFDELNLSAPEMVLDLHRAYAAAHAD
ILETNTYGANRYKLKAHGLEEQTAAINRRGVELARQAADEELYVAGAIGPTGVTVAQLGT
IPEAEMLELYGEQAAALAEAGVDLFLLETFQDLNEILLALRAVRRVSRLPVIAQMTYDEE
GKTTLGVQPETVVQALLGEGADCIGANCSVGPHAMLEVIRRLARAGAPFITAQPNAGLPR
LFEGRLLYMSTPEYHAEYARRFISAGASVVGGCCGTTPEHIRAIAGAVRALQPRKEASTV
VLHPEVESAVQPIPRPEKSALAARIGRKFVLSVEVLSPRGISVEGVLAGVRKLAGFGVDA
INIPDGPRASSRMSPSALALLIERSLPVETILHYCCRDRNLLGMQSDLLGHYALGLRNIL
IITGDPPKLGDYPSATAVFDVDSIGLTRMVNGLNHGHDLAGNPIGAPTGWHIGVGANPGA
LDLDLEIARLEQKVAAGAEYLLTQPVFDPHQLESFFKRTEHLRIPVLAGIMPVVSHRTVE
YLNNEVPGVVIPEEIVRRFAGAADSAHARETGIEIARKGILELRQFEQVSGLYVMPPFTK
DKYDVAIEVLQVVQ
>A0A846H3X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hassallia byssoidea VB512170|TrEMBL
MLDTSKAALTCFRQAAKAGDFLITAEVTPPKGGNPAHMVSMAATLKGRVHAVNITDGSRA
VLRMSSLVASAILLQNGIEPICQLACRDRNRISLQADLMGAHALGIYNILALTGDPVKAG
DHTDAKGVFDLEAVRLLQVIQKLNHGFDCNEKPLTDGSTDLFAGAAVDPQCASWSGLQSR
FERKLQAGAQFFQSQLITDFERLEKFMDKIAAGCDKPILAGIFLLKSAKNAQFINRCVPG
VNIPDHIIDRLAQAKDPLEEGVKIAAEQVQIARQLCQGVHMMAVKREDLIVPILDMAGVA
PVKQLVTV
>A0A8G1I0S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ERGC3:05|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYQQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2V1AGD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] duobushaemulonis|TrEMBL
MKISKKLDDAHSCSNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYELNPIFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALSKAHASGCQNILALRGDPPLD
GSESTGDFKYAKDLIRYIRKNYGDHFNIGHPEEEDDVKLLSYLKEKVDAGADFIITQMFY
DADNFISWCSKIRKIGVEIPIIPGIMPISTYSAFIRRAKWSQVKIPEHFLQALDPIKEDD
YAVREKGTQLVGEMCQKLIDSGYVNHLHFYTMNLERSTIMVLEHLNLIEHVKDNAVVGDE
LPWRKSLHPMRSKESIRPIFWQNRKYSYISRTSGWDEFPNGRWGDSRSPAFGDIDLSATE
LLRQSPKRAFELWGCPQTLGDLSQILISYLQGEIKSLPWSDGPIGDDTEVLKPALIEMNK
KGIFTLNSQPALSAVRSNDEVFGWGPKNGFVYQKQYLEFFIHRNALNTLLQRVEEHNARD
AHSVVTYYAVDKQGTLSTNAHDDDINAVTWGVFPGEEILQPTIVEKVSFLAWKDEVYRLL
DEWVKIFHTKSVKEEVEEAKIDAFSTLLTGFGDNFVLCNFVNNDFTSGNNIIFDLFRDLP
VASL
>A0A0X8K350|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MHDNEPTGPTAAAGSRAAGLSSAETGSARRLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPAGGINGGEYEGSVRGTEVSRCKAVPCVRAVQEQTNPSEFVLAH
VLESSTIPLMAHLTCIGYRKQEAVEIVTRFLRMGVRRFLALRGDPPAGTRADEVAGELRH
ADDLVRVIREVEADFFGDGKRHVTIAVAAYPATSDHIEAIEVLAAKQAAGADMAITQVFY
DAADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSTLGSASGAT
LVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGATPDREVRDA
VDRGYLQATPGRGPSFLRCGSPGAALSSRHPVPPHTTITKENA
>A0A7K9KI56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dicaeum eximium|TrEMBL
MVNETQHSCSASSSSRCDGSSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCKQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEADGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLMHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>W9Z7Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capronia coronata CBS 617.96|TrEMBL
MHISQKLALAHENKKPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
QLTCEMVNAAQSHYGLETCMHLTCTDMERTQVDEALRLAYKAGCTNILALRGDPPRDQEK
WEAKDAGFRYAKDLVRYIKARYGDHFDIGVAGYPEGCDDHRDVDLLIEHLKEKVDAGATF
VVTQMFYDVDIFLDWVQKCRDRGIKVPIIPGIMPISTYAAFMRRASWTKCHVPPEWYEAL
EPVKNDDAAVRDIGKDLIAQMCRRILDAGILHLHFYTMNLAQATRMILDELALTPETSGR
RLEKPLPWRQSLGFNRRDETVRPIFWRNRNTSYVARTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANIKLWGKPKSLREITTLFVHFLHGDLDRLPWSEGSISAEADSIKSDLV
ALNQRGLLTINSQPAIDGAPSSHPIYGWGPPGGWVYQKAYLELLVFPSIFNTVLERLNAN
ENLTYYAVNRKGELHTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WAKCYPAGSGPRKLIEKMMDECYLVNIVNNDFHQTHEIFRVFDGLEVQDLDMTFEDTPAE
HQTNGTRDVLKGDAPVTEVEKSIVSENQQKVPFQTNGHVLSN
>A0A2E3Q9Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira sp|TrEMBL
MMTVPEIKAVRKNLRVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGTTRGR
THGSVTRIQKETGIPAAAHLTCVGHTKEEIDEIARSYWDEGIRSIVALRGDMPEATGKYE
PTPGGYAYAVDLVAGLKEIADFDISVSAYPETHPDAPSADFEIEYLKRKIDAGANRAITQ
FFFDNETYLRFRDKCVAAGIDAPIVPGILPVTNFASLLNFAGMCGASVPQRLHWRFEGLD
EDPDTRRMVAFHEAISQVEGLISEGVTDFHFYTLNRAELTYAICHALGIRGTEQAAA
>Q4X140|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)|TrEMBL
MHVKDMLTDNESAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEA
WEATEGGLRYAKDLVKYIREKFGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
VITQMFYDVDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEAL
EPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQATQAVLEELKLIPSEETP
LQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSIRDITQIFVRYLEGKLDRLPWSDSPISGEANAIKDNLVQ
LNSRGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNP
DLTYHAVAKNRELRTNTRDSPNALTWGIFAGREIVQPTIVDTISFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQDIMDNWYLVNIVNNDFHNTYDLFDLFNGLEVKDLDLEVGPDTAETK
SQPNGAAPEEVAIKN
>A0A4Q2RKT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides glacieisoli|TrEMBL
MRNKRHAATMIRLLENARYEVLPTATTEDKVLEHLPRDRTVTVTASPSKGLEATFDLTER
LAGHGYTAVPHIAARMVTGRAELTEIVERLVGKGITSVFVPGGDAEAAGDYPDALALLED
LKALGSPFSHVGITGYPESHPTIHDDLTVQSMWDKRHYATHIVSNLTFDPAGVRDWVGRL
RRRGVTMPVLLGMPGPVERTKLLGMATRIGVGESTKFLAKNKGLFARLAAPGGFTGESFL
EKCAPALGEEGALVEGLHVFTFNQIGETEAWRTDLLDRLRGV
>A0A420G3Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium deltaense|TrEMBL
MIIKRITHKLPDISAASIIPASIEASPAQVLGSTDLADLFPQGVRVYLTDTGAASQERLV
EAAGHLRDLGYEPVPHLAARRIPSRAAFEEQVKRLAGEAGVTDVLVVGGGVDRPAGPFAS
SMDMLSSGIFDRCGIRQIAIAGHPEGSPDFNEETAMAALRLKRDFAERSDAVMRIVTQFG
FDPARFIAWAEGLAASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESIVGPIERHWQTNPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGAADRSAS
PDSMAG
>A0A2X1B6K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas vesicularis|TrEMBL
MASSASLNLADARALLLSPLGPVARAGSNRDAVRVSFEFFPPKTDEAEANLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIITETSLRPAAHLTCVEASREEVDEVIEGYKAIG
VDHIVALRGDPPGGAGIGGAYQPRADGYANATELTAAINRIGGFDVTVGAYPERHPESPS
IDHDIEVLKAKIDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLQ
RMCGACGASIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETAAVQ
>A0A3S4YJ98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus pleuropneumoniae|TrEMBL
MSYAKEIDHLNHTLADLNGNINASFEFFPAKNEKMEMLLWDSIHRLAPLKPKFVSVTYGA
NSGERKRTHSIVKRIQQDTGLAAAPHLTGIDANPEQLRIIAQDYWENGIRHIVALRGDKP
AGYAKKSFFAKDLVKLLKEVANFDISVAAYPEVHPEAKSAQSDLIYLKQKVEAGANRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVTNFKQLQKMAKITNVKVPHWMHKMYEGL
DDDQTTRNLVAASIAMDMVKILSKEGVKDFHFYTLNRSELTYAICHALGVRPT
>A0A2E2SX62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira sp|TrEMBL
MTVKNDIAPQGTSHGDLRVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGST
RDRTHSSVTRIQGETGIPAAAHLTCVGHTKEEIEGIARNYWDEGIRSIVALRGDLPDAGD
KYVPTPGGYPYAVDLVEGLKRIADFDISVSAYPETHPDAPNADFEIEYLKHKIDAGANRA
ITQFFFDNEVFLRFRDKCAAAGITAPIVPGILPVTNFGSLLKFADMCGASVPKRLHWRFE
DLDEDPDTRRMVAFHEAISQVEGLMAEGVTDFHFYTLNRAELTYAICHALGIRGVAQAAA
>A0A258A4Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium 32-42-5|TrEMBL
TDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFNGKGTPVAPHLSCIGD
DKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVRFIREHSGDHFKIEVA
AYPEMHPQADSFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFIDRIQKEGVNIPVAPG
IMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHEVIVKLCERLIAGGAP
SLHFYTMNTTDPTRQLVLDLGLA
>A0A1F9NF85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula sp. GWF2_41_7|TrEMBL
MSELYTQSRLEKVLKAGHLGVTSECGPPRGSDAEEVKKKGLLIKDYVDAVNVTDNQTAMT
RMSSLAACIHLKLLGIEPVLQMVTRDRNRVALQSDILGAASFDIPNMLCLSGDHQSFGDC
KSGQNVHDLDSMQLVQTVRYMRDEGKFLGGDAIKRPPRIFVGAAANPFADPFEIRVPRLA
KKIACGAEFIQTQCIYNIDKFKEWMRQAVERGLHEKAFIMAGMTPMKSVGMAKYMKNRVP
GMDVPDEIIARLAGVPKDKQAEEGINICVEHILELKEVKGVAGFHIMAIEWEEKVPEIIK
RAGLYPRPQV
>A0A7X8GPQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistaceae bacterium|TrEMBL
MFIRDLFRKKGPVISFEVFQPKTDAPIAGVYRTIEALKDLSPGFISVTYGAGGTSRDRTV
EIASRIRNGYGIEALAHLTCRAHTPQEIDEICEDLLDEGVQNILALRGDPQPGEGEKRET
SFSYACDLVRYLRRNHFGNFCIGAAAYPEGHIECQDPSRDLDFLKAKVDAGAEFLITQLF
FDNDLFYRFRDEACRRGIDVPIVAGIFPVLNAGQVQKIVSLCGVSLPPRFTRIVARYANS
PAALAEAGVAYATDQIIDLLTAGVDGIHLYTMNRPETTRRIMGNIDQIRKTAFPEGSEEG
>A0A7L6YZB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. RHB20-C16|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGSGKPDMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGI
>A0A1J5SAK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MKVTEHIAQAKNTLVSFEVLPPLKGKTITSLYDHLDPLMEFKPSWINVTYHRSETMFKKK
ADGTFEKVDVRKRPGTVGICAAIMNHYKIDAVPHLICGGFTKRETEDALIDLNFLGIDNV
LVLRGDAAKNETSFEPEKDGNFFAIDLLKQVSNLNNGIYIDKDIQNGSKTNFCMGVAGYP
EKHFEAPNLEIDLARLKEKVDAGAEYIMTQMFFDNQKFFDFVKSCRAIGINVPIIPGLKP
ITTKKQLSVLPRIFHVDIPTDLSNEVLKCKTDADVEAIGTKWLIQQSKELKQFGVPVLHY
YTLGKPKIIWNVVKEVL
>A0A0R1QAG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus nagelii DSM 13675|TrEMBL
MTNLAEKSSFSFEVFPPKTAVNNQKIFQTLDELHDLQPDFISVTSSNRTLNFENSTLKLA
DYVQNKLKVPGVVHLTARYFDRKQIDRILVELKFLGIKNILVIRGDLAPGRPPKKDFQHA
SDLMAYIKSKDANFRILGACYPESHPESSNKISDIHHLKEKVAAGCDCLLTQMFFSNETF
YQFQENCALADINVPLIAGIMPIVNRAQALHVLKQSECCLPKKFTQMLDRYQTDPTALKA
AGLAYAINQITDLVTNRVAGVHLYTMNQANVARYIYQATKSLFTIKNPV
>A0A1I3DA23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas sp. OK307|TrEMBL
MAKKNFSIEFFPPKTPEGAEKLRVTRAKLAELHPRYFSVTFGAGGSTQKGTLDTVLDIRS
EGHEAAPHLSCLGSSRESLRSILAQYKDNGIKRLVALRGDLPSGYGAMDISSGEFRYANE
LVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDVQRYVSKVKAGANGAITQYFYNADAYF
RFVEEAQKLGATIPVIAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTDSIRAF
GLDVVTQLCERLLAGGAPGLHFYTLNQSAATIAIWQRLKL
>A0A3D2VSZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Competibacteraceae bacterium|TrEMBL
MALNFDDIPDDPSLPMPILPGHTSAGRLERVLRAGAFAVTSEMDPPDSADAEEVFARARI
FDGYVDAINATDGAGGHCHMSSVAVAALLIRAGYAPIMQIACRDKNRIAIQGDILGGAAM
GVCNMLCLTGDGVQAGDHPQAKPVFDLDCLSLLEIARGLRDERRFQSGRKIGSPPRVFFG
AVENPLAPPRDWRPHRLAKKVAAGAQFIQTQYCFEIPPLREFMKKAEDLGLLDKVFILIG
VGPLRSAKSAEWMRGHVPGVYIPDAIIRRLAGADDQRAEGRSLCVELIQEIREIKGVSGV
HVMAYYQQEAAAEIIERSGVLQGRVPWYPGIRTQTRQ
>A0A238HC86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia singularis|TrEMBL
MNPIELSFEFFPPKTAQGVDKLRTTCAQLAPLAPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFVRKVKAGANAAITQYFYNADAYFRFVD
DAAKLGADVPIVPGIMPITNFSQLVRFSEMCGAEVPRWIARRLESFGDDKESIRAFGTDV
VAGLCRRLVDAGVPGLHFYTLNGAAATKAVCERLGF
>A0A433E973|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HSID18069|TrEMBL
MTTVHPALSYELYPPRSHASCESLLKTIAELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICMGHSVADLERSVRLILGLGVRGFLALRGDIPPEDTRPLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAAHLAGVQMPIIPGIMPVTSLTRLTKLCELAGLEVPRELAHRLETASDP
REMHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>A0A3B9PGE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistaceae bacterium|TrEMBL
MKIKGLFSHGRPVVSFEIFPPKRDLPIDSIYATIEELKSLQPDFISVTYGAGGSTKERTV
EIASSIRNVYGIRALAHLTCVGTSKEEADSILKELLSCGISDVLALRGDPPAGMDIDSVP
RHFRYAADLVAHIRRVYGDAFSIGGAAYPEGHVECDDIELRLLHLKAKVEMGVDFLITQL
FFENEAFYRFLEKARGIGINVPISAGIMPVVNKKQIERIVTLCGASIPPKLARILSKYAD
APEALEDAGVAYAVDQIVDLLSSGADGVHIYTMNRPWVARRIMESIARLLRELKKPKERA
EVS
>M8B9B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium tumefaciens str. Cherry 2E-2-2|TrEMBL
MPDISAASIIPASIEASPAQVLGSTDLAGLFPQGVRVYLTDTGAASQERLVEAAGHLRDL
GYEPVPHLAARRIPSSTTFEEQVKRLAGEAGVTDVLVVGGGVGRPAGPFASSMEMLSTGI
FDRCGIRQIAIAGHPEGSPDFNDETAMAALRLKRDFAERSDAAMRIVTQFGFDPARFIAW
AEGLAASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTTLAKGHSPES
IVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGAVDRSASPDSMAG
>A0A176E2B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. HI0028|TrEMBL
MSPTMDQMREAQRALEAPLFSGLPGDIDVSFEFFPPKNAAMSETLWQSVETLAPLGPRFA
SVTYGAGGSTRERTHQQVVRIQNEARIPAAAHLTCVEATREEVDEVARHYWDEGIRHIVA
LRGDAPDGQSQYAPHPGGYANAVELIAGLKKVADFEISVAAYPEVHPDSPDRQADLDNLK
AKFDAGATRAITQFFFDPQCFFDFRDRAAAAGIDGEIVPGIMPVLSFAAVRRMSGLCGTA
IPPWMEGLFDGLDDRPAARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRAKAGR
>A0A1G9G202|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. ov407|TrEMBL
MSPPSLIDTHPNLAGAAPVALSYELFPPRSPAAAESLWTTIGELEATDPDYVSVTYGSNG
SNRSTAVDLINRLVQETTLRPLAHLTCVGNSPQELAEIIGDLLDVGVRGILALRGDQPKD
GATPPPGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLLTRARRAGVTIPIIPGVMPLTSLRRLARLGELTGVE
PAPELIERLSAAGTDAERIRVGVSATVDLANAALDAGAPGIHLYTFNEHAAALDVLDKLA
LPRPHRGNRHGVGRIDASRRAASGQLAS
>A0A2U2PHT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararcticibacter amylolyticus|TrEMBL
MKITEHISNSNGKTLFSFELLPPIKGQSIQSIYNAIDPLMEFKPPFIDVTYHREDYIYKQ
HANGLLEKVTYRKRPGTVAICAAIINRYKVDAVPHLICGGFTREETENALIDLQFLGIDN
VLVLRGDARKTDASFIPTQGGHAYATELLQQVASMNQGKYLHEDHDANKTDFCIGVAAYP
EKHFEAPNIETDFKYLKQKVDMGANFIVTQMFFDNKKYCDFVKQCRDHGINIPIIPGLKP
ITTSKQLINLPKIFHIDIPLELSDAVTACKSDAEVKEVGIEWMIQQCKELVEFGAPVLHF
YTMGNPEPTYRIAKAVF
>A0A1E3L022|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus nuruki|TrEMBL
MKPDLRSKWTDSVIIGDGAMGTYLYQLGFPVGISYEELNLIRPHIIEDVHRQYVNAGAQM
IETNTFSANYDRLSKYGLEDKVDEINRAGVRIARAAAGDQAYVVGSVGAIRNGKRTNIPR
SELRQYFRQQVSSLLDEGVDGILLETFFEVEELAIALRQVRKLTDIPVMCQLTVEDAIRT
LDGFALPDAFALLTDAGADMVGLNCRVGPNGTLHALEAIQGKVSLPLSVYPDAGVADYVD
GEYRYGASPAYFGQRSVRFAELGARVIGGCCGTTPEHIAAIARALEGYTPETLDFSNVQK
PTPQISVTIENAIMDESDRNGEDVPPTLVDLVRERPTVIVELDPPRDLDITRFLKGAAAL
KEAGVDALTLADNSLAVTRMSNMALGHIVQREAGIRPLIHIACRDRNMIGSQSHMMGFDA
LGIDHVLAVTGDPSKFGDLPGASSVYDMTSFDMIKMIKQLNEGIAFSGKPLKQRAKFVVG
AAFNPNVKHLDKAVVRLEKKIAAGADYIMTQPVYDVQLIADIREATKHLDIPIFIGIMPL
ASGRNAEYLHNEVPGIQLSDEVRGRMAGLEGEEGRATGVVIAKELLDVAMEHFNGIYIMT
PFMFYDMSVQLTEYIWTKAKRRPNPLFHTR
>K2P7Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus xiamenensis|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSLDEIKR
SFREQLYILLNEQPDGLLLETYYDIEEAKAVLQIARKETALPIVMNVSMHEQGVLQDGTP
LKDGLSELSALGADVVGINCRLGPYHMIQALEGVPILENSYLSVYPNSSLPSFEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTMPQHISAMAEAVKDLAPITEKEVKVLKEEMIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKSAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIREIMAKAGEDKEKQRTEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKETNAHVNYH
>A0A3P0X9C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidipila sp. EB88|TrEMBL
MSNRLQQLFGDRPVLCDGAMGTILYDRGIFINRCYDELNLSDPDLVRSIHEEYLQAGAEL
IETNTFGASRFRLQRFGLEDKVEAINQAGVRLARDAVRQLKEKQANDAWVAGSVGPLGIK
MEPLGKISREEARAAYAEQIRALASGGPGVGVDLLIVETVLSLAEAEQALLAAREAAPDL
PVVVMVTVDEESLCLDGTQPELAAARLANWGADGIGVNCSTGPAAVLSAIESMAGGTHLP
LFAMPNAGVPRAIDGRNIYLCSPEYMASFARKFLKAGVQFVGGCCGTTPAHIRAMRANLR
AQSAMKAGAREVEATEARGGPRVEVLPDDAVETAPLAQRSTIGRLIAERQFVTLVEIVPP
RGIDTRKELAGARLLAEHGVDAINVPDSPRASARMSAQSLCIQIQQNAPKNAPIETVLHY
TCRDRNVLSIQSDLLGASSIGLKNILCLTGDPPKLGNYPDATAVFDVDAIGLVNIVRRLN
HGLDIGGNSIGESTGFTVAVAANPGVPDIENEIRRFAYKVEAGAEYAITQPVFDLRLLES
FLRRVEQFRIPVIAGIWPLTSLRNAEFMKNDLRVAVPDEIMVRMGAAEGPEASRDEGVRI
AQEMLATARPMVQGVAASAPFGRYNTAIETLSSVLPSRK
>A0A0C2S4C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MSTSHRPSISFEFFPTKTDAGHEKLLATARQLAAQQPDFFSCTYGAGGSTRDRTLNTVLQ
LDSEVKVPTAPHLSCVGDSKTELRGLLNLYRDAGIRRIVALRGDLPSGMGLASGELRFAN
ELVEFIRSETGDHFHIEVAAYPEMHPQARNFEDDLSNFARKAQAGADSAITQYFFNADCY
FYFVERVRKLGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIESIQA
FGEQVIAEMCEKLLAGGAPGLHFYTLNQAEPSLAICSALGLSR
>E0TCA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvularcula bermudensis (strain ATCC BAA-594 / HTCC2503 / KCTC 12087)|TrEMBL
MSSVNVSFEFFPPKTDAMEQTLWASVEKLAPLDPAFVSVTYGAGGSTRERTHRTVSRLVQ
ETGLPVAAHLTTVAASREDIDAVLRAYWAAGVRHIVALRGDPPGGLGAAYEPHPDGYANA
AALTEAARRVGDFEVTVGCYPETHPESANREADIDWLKQKVDAGATRAITQFFFDNNVYE
RYVDDVRRAGIDIPIVPGIMPVGSYKALSRMAGLCGATIPPTIKDCFEDLDNDPETRRLA
AVTTVADQCRDLVRRGVEDLHFYTLNRADIAYAVCHLLGIRPTHADGRTS
>A0A1F8P9C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_16_50_9|TrEMBL
MTSRFKEALNSGKFVITSEVAPPKGPNLEKMLHHIDILKDKVDAINVTDHQSSVMRFPSL
GGCLAIKEKGGEAIMQMTCRDRNRMALEADLLFAFSRGIRNVLCLTGDAVPVGDHKEAKG
VFDLDSLQLLKAIRQMMSGQDLGGNKLEGTVEFCAGAIVTPEARPIEPQLIKFEKKVEAG
AEFFQTQAIYDLENFARFMEHARKFKIKILAGIVLLSSARMAKYMTENVPGIFVPQNLID
ELSKVPKEAMLAKGIEIAGRTIAELKKKSICDGVHIMAIGKEEVVPDILSAAGL
>A0A3T0K181|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVTEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A5N6M5C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mikania micrantha|TrEMBL
MKVIEKILESTAAGDAGKTVFSFEFFPPKTEEGVENLFERMERMVAHNPTFCDITWGAGG
STAELTLEIARRMQNLVCVETMMHLTCTNMPVEKIDHALETIKKDGIQNVLALRGDPPRG
QDKFVQIQGGFACALDLVEHIRKSYGDYFGIAVAGYPEAHPEVIESNGLATPEAYAKDLA
YLKRKVDAGADVIVTQLFYDVDNFLKFVNDCRQIGITCPIVPGIMPINNYNGFIRMTGFC
KTKIPSEITAALEPIKDNEEAVRAYGVQLGTEMCKKIMASGIKTLHLYTLNMEKSALGIL
TNLGLIEESKISRPLPWRRPTNLFRLKEDVRPIFWANRPKSYITRTTGWEQYPHGRWGNA
SNASYGALTDHQFMRPRARDKKIQEEWVVPLKKFDDISEKFMKYCLGQLKTSPWSELDAL
QPETKIIDEQLASINLKGFLTINSQPPVNGAKSEIPSVGWGPAGGYVYQKAYVEFFCSGD
KLNALVEKSKAYPSLTYVAVNKDGNLVSNVGINDVNAVTWGVFPAKEIIQPTVVDPSSFL
IWKDEAFEIWSRGWAQLYSEDDSSRTLLQEVQNTYYLVSLVDNDYINSNLFTVFKDF
>A0A238KFE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maliponia aquimaris|TrEMBL
MQRPEISYEFFPPKNIEATFRLWDAVQVLSPLKPRFVSVTYGAGGTTRDLTRDVVATLHK
HSGLRTAAHLTCVDATREETLAIADDFAAAGVTDIVALRGDPPKGSAGFVPHPEGFANSI
ELIESLADTGKFTIRVGAYPDCHPEAGSMQANIDWLKRKLDAGATEALTQFFFEAETFFR
FRDSCAKAGIDKAVVPGILPIENWNGARRFAESCGTHIPAWLIDAFEKAQRDGREDLLAT
AICTELCSDLLEGGVDKLHFYTLNRPELTRDVCFALGVTPEVKFEQVA
>A0A3Q8YQS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEVRLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVRRILNETTLTPAAHMTCVDAARHQVDAVISEFAEMGVTRFVALRGDPAAGVGT
AYRPHPEGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHESEAT
GSAAA
>Q8Y389|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia solanacearum (strain GMI1000)|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILDTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRKEMNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>A0A2H5WDF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR12|TrEMBL
MSEPRSHLDRLLRSDTFVVTAEMPTVDGADPAAVLRAAERLRGRVDAVNCTDNSAAHPHL
SSVAAGHLLLDAGVEPIVQLTCRDRNRLALQADLLGAAALGVRNVCLMTGDDVTAGDHPE
AKPLYDLDSIHLIRTARILRDAGTYLSGRPLDSPPNFLVGAVENPFAPPLEFRPMRLGKK
IEAGAEFIQTQICFDLPRLRLFLARAGDLGLLGRVPILVGVFVPRSARAVRYLRDEVPGI
DVPEGILARMASVPEERQWEEGVRIAIEIVEEVRTLPGVRGVHLMAIRNEEGIDAVLEGA
GLLPRPARVPVG
>M1PRC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocapsa sulfexigens (strain DSM 10523 / SB164P1)|TrEMBL
MAQPVSNIFRDSLRNNDEFTITYELVPGRGSGGKRLEKILQLAELARDDGRIKALSITDN
PGGHPALSPISLGLDILAMGISPLLHFSLKDKNRNLAESQLFECHRHDLLNLLVLGGDFP
RYGFQGQAMPVFDLDSTQLLTLIEQLRHNFTVTRGAPGQAMDLPRMDFFAGCVVSPFKTL
ESEQVWQYVKLLTKIQCGAQFVISQLGYDIVKYQELIQFINEQQLRIPVLANLFVPSLAV
ARIMNKGLVPGVILPDALLQKMEDEAKSSDRGEEARLLRAARMLAALRETGYSGIHLGGN
NLSFKSISFILDKSEDFTEKTDQAETHFPEPGTWYLYQTSCRTPRKRTLPFLFSSNHFIH
KQIFAEKGLFFSIARKLSIKALSNSFLSRTYTLVEHLIKKILFHCRMCGDCTLAESSYLC
PQSGCPKKMINGPCGGSNNGYCEVYPNKRLCFWVRSYHRGLEPDCHTIHSPKPIPPKDWS
LDKTSSWLNYFSGRDHCELQVKKKKAEY
>A0A523HL52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldithrix sp|TrEMBL
MKRRNFLKELENRVILFDGATGTMLYNRGVFINQCFDQVNLTNTRLIKEIHTDYANAGSD
VLQTNTFGANQFKLAQHGLSDSLEAINYQGARLARDVAGNQLFVAGSIGPLGVKIEPWGK
LSRKEAKDAFKEQGQALVNGGVDLFVLETFSDLSEIEQAILALRELGDLPIIAEMTIDES
GNSLYGTATETFTHQLDKWGADVVGINCSVGPPPMMDALEKMVHVTKKPIIIQPNAGNPR
VVDERNMYLASPEYMGEYAMRFIKAGARLVGGCCGTTPEYIKAMEKSVRMLSPRQHNFSI
RVPKETIEEATPIPWEEKSKFAAKLAKGELVTSVEIVPPRGSDPSKVLESCRQLKEFGVD
GINVPDGPRAMCRMGAQHLSILIEQNVGIETLLHYCCRDRNLLGMQSDIMGLYAVGLRNI
LIITGDPPKMGDYPDATAVFDVDSIGLTNMVDRMNHGIDLGGTKLDAPTGFHIGVGLNPG
ALDPALEIRRFEWKVEAGAEYAITQPVFDPQILLEFLPKIKHVKIPVIAGIWPLVSFRNA
EFMNSEVPGASVPEKYMERMRQAQEISKEEARAEGLRIAQEAVAQSREHVKGFQVSAPFG
KVEYSMQVLSVLKEFGGDV
>A0A7W0IUD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSFRESLESGKFLVTAEVGPGKGTDVEHLLKAADIIKDRVDAINVTDLQSSVMRLGSMAF
SHLLTDMGIDPIFQMTGRDRNRLALQSDLLSAWVLGIRNVLALTGDHPTMGDHPHAKPVF
DLDSVSLLEMIGKLNSGYDMAGNELKGAPEFLPGAVVNPGADNEAALDLQIMKMEKKIEA
GAKFFQTQAVYDIDLFEKFIRRVEGFKVPIIGGVILLKSAGMARFMNKNVAGVFVPIPLI
KEMTDTKDKVKKSVEIAARIVKRLKNLCQGVHIMALGWEKMIPAVLDQAGI
>A0A6N7V835|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. BL-252-APC-1A|TrEMBL
MDPTAALLDDFSLEMTGKDVPALREAQDALPSGTRVNVTFLGNEDLPMRLAAAAAVKAAG
HVPVPHISARRLGSAAELEKFLGALAEAGAVENVFAVAGDPAEPMGPYADSLAVIASGLP
AAHGARHISISGYPEGHPDIDNQTLWSALEQKLAAIRDQGLDASIITQFGFDTAPVLAWL
EELRSRGIDAPVRIGVPGPAGVKRLLGYARRFGVGTSASIAHKYGFSLTNLLGTAGPDRF
LTELAAEHDPGRHGVVKLHFYTFGGLRPTAEWVRSFRGY
>A0A847H523|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Gastranaerophilales bacterium|TrEMBL
MKLKEIYKSSKLAISFEVFPPKMKEIAEKEQKIQSLLDELGLLSRYNPAFISVTYGAGGS
TQETTFDVVLQIKEKLNIQPMPHFTCVGSTRTEILEYIKKFEEQGIENILALRGDPPKGQ
EQFVKPKDGFGYAYELVKFIKAHTDLGIGVAGYPECHQECPGLDIDIQYLKQKVDCGADV
VITQLFYDNKRYFEFVEKAQAKGIIVPIIPGILPITTYSQLDKIGSMSGCALPQEFKENL
EKHRDNPEAIKSIGLEFAINQCSELLANGVRGLHFFTLNKAFATG
>A0A7K5SIS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Urocynchramus pylzowi|TrEMBL
MVNETQHTCSASSSSRSDGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITAHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAQSYEADLRHLKEKVFAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>D2ZW31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria mucosa ATCC 25996|TrEMBL
MSYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHSIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DNDQATRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A7C5DRQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
AEFIQTQCIYNLDKFEEWMKLARDRGLHEQVYILAGMTPMKSAGMAKYMKNRVPGMDVPD
TLVKRLADTPKEKQAEEGIKICIEDIQRLKEVEGVSGFHIMAIEWEEKVPEIVEKTGLYP
RPQIQE
>A0A7H0FUV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter solisilvae|TrEMBL
MPLPALSFEFYPPKTDEQRAQLDKTAARLKSLKPDYVSCTFGAGGSTLSYTPETIERLHA
HHGLDAAPHLSCVGGTRAELGELLLRYKAMGCRRIVALRGDLPSGMGRAGDFRYASDLVE
FIRTEYNGFFHIEVAAYPECHPQADDALADLRNFKRKVEAGANGAITQYFYNADAYFRFV
DDARRLGIDVPIVPGIMPISNFTQLRRFSEACGAEIPRWIGKRMQAFGDDVDSVREFASD
FVASLCQRLIDGGAPGLHFYTLNLSKPTLGVLARLE
>A0A3A5AA92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MAEQKEIKAGSNLEKVLKAGHFAFTGELGPPRGANVEHVRKKAAFLKGNVDSVNITDNQT
AVVRMSSWAASLILIQEGLEPNFQMVCRDRNRLAMQSDVLGAYALGIRNMLCLSGDHPKF
GDHPTSKGVFDIDSIQLIDMVRKMRDDGKFLSGGELDTPPKMFIGAAANPFAEPHEWRVF
RLAKKIKAGADFIQTQCIYNMDRFREFMKKAVDMGLHEQCYILAGVTPMKSVGMAQYMAK
SVPGMDVPESLIKRLRDAGKGKASEEGIKIAVEQIQEFKEMKGVAGVHLMAIEWEHMVPE
IAEKAGVLPRPKV
>A0A413HDZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. OF03-4AA|TrEMBL
MRVDEVFKQAASQGATPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A0P7E714|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cobetia sp. UCD-24C|TrEMBL
MTSILTIPDSPQLPPAERDGNIGHLERVLRSGQFAVTAELAPPDSADPQEVHARAQLFAG
HVDAMNATDGSGANCHMSSVAMCALLAREGHETVMQISCRDRNRIAIQGDVLGATALGIR
NLLCLTGDGVQVGDHPEAKPVFDLDSLSLLEIVAGLRDKHAFASGRSLTSAPKVFLGAAA
NPFAPPFAFRPHRLAKKIAAGAQFIQTQYCFDLPRFQDFMHRARDLGLLEKCFILPGVGP
LASARTAEWMRRHVPGVHIPDDVLKRLKGARDQKAEGRDICIEMIQQLREIEGVSGVHIM
AHRQEAFVPEIIQRADILGARIPWTPEPRPTPSP
>T2JZM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocosphaera watsonii WH 0402|TrEMBL
MINHFRQAVQNKEFLITAEVAPPKGGNPTRMLEMAKQLKGRVHGVNITDGSRAVLRMSSM
AASALLLQYGIEPICQMTCRDRNAIALQADLMGAYALGLRNVLALTGDPIKAGDHKRSKP
VFEVESVRLLKMIDKLNEGIDFNDKTLADEPLDLFPGAAVDPQSRSWSGLQKRFERKVAA
GAQFFQSQLITDFEKLDKFMHQIAANSDKPILAGIFLFKSAKNAQFINNNVPGVEIPESI
IKRLGEAEEPLKEGIKIAAEQVKQAQKLCQGVHLMAVKREDLIPEILDQAGIPPMVSQ
>A0A3A4TFU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MPQTSKLATMINAGNFIITAEFLPLPGADSKAVEDAAGFFKDRITAVNVADNPHGPILSS
LAGSVILERCGIEAVYQVVTRDRNRIALQSDLLGAAALGIKNVLCLSGHHQTLTVSRASA
SVYDIDSIQLAAAVKQMNDDAVLIDGTKINGDFSILAGAVATPDMKPLELNIMRLAKKVA
AGAQFIQTQAVFDLDAFALWIKEAKQAGITSKTAILAGVMPLESASEAEALREKYTDLVI
PDSVVERLKAAGDDTAQAKEGMAICVETIKKIKSIEGVRGLHILSGGKEHLVPEIIKAAG
L
>A0A421JLD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spathaspora sp. JA1|TrEMBL
MTTVKEKIQSLRPNEKFISFEFFPPKTDSGFRNLLARLNRMSALNPLFITVTWGAGGSTS
EKSLDLAATCQNDLGLTTVLHLTCTNTNKEIIDDALARAKRNGIRNILALRGDPPRTQEY
WTPNCEFNGAVDLVQYIRQQYGDYFCIGVAGYPEGHVDGSDTAGQNPKKDMPYLVDKVKA
GADFIITQLFFDVDQFIEYEQLLQGYEELKNIPLIPGLMPITTYRVFTRASKLSHASIPD
EILKELEKVSNDDDAVKTLGVKILSEIIQNIDAKIGSRIKGYHFYCLNLEKAVASIIDQS
KVLHPILDMPHHSVEHDDAIVSESEGETEEQVIPASSIQNGISRRRKSSLVNENELAISP
ATKELVSKALLKDRQVLVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPNLK
IHTPAEASLKWGSPETKAELTQVFIDYLSGKIDVLPWTDTPLSPETALIQEQLFELNKKG
WFSLASQPAVNGCKSTDRMFGWGPRNGVIYQKAFVEIFVPKQEWETILAPRLQASFDNKT
ITYYMGDKTGDIKSNLLSEPDARYTKNAVTWGVFPSKEVIQPTIIDFESFKAWNEEAFAL
WLQWARCYKINSKSFQLLDSIYNEYVLVSLIHHDFPEENALWDTLLGE
>A0A0H5SIL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbinix hemicellulosilytica|TrEMBL
MRISSLFGKNKVVFSFEVFPPKKTSPIDTIYKTLDDLKDLKPDFISVTYGAGGNAADTST
CDIV
>A0A838TB65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MDLLDELQSRLVCGDGAMGTMLLDEGIPLERCLEELSISEPERVLKVHEAYVAAGARVIE
TNTFGASRVRLDRFGFGEQTLEINAAAAGIARGAAQGKDVFVAGSVGPLGISADEAETRG
IDRVAVFREQITGLLDGGADAIFLETFLDYDELALALEAKMHLSKAPVICSLACEQEGRL
PSGLALVEAFRKLTALGADIVGVNCLNGPQAMVHLLERIPRGFLISAYPNAGYPKYHEGR
FIYYTAPDYFARMAGEMAAQGARLIGGCCGTTPRTIAAMAAALAELEPARSKAVGAITEA
VRAPAPRVLPPSEESLLDRIAAGHRVIICELDPPKTLALEKYFTGALALVRAGCDAITLA
DNSLAILRVSNLAIGAMLKERFGITPLLHMSCRDRNVLGLQSELLGMAALGMRHVLPLTG
DPARVGDHPGAASVYDVNSVQLIGIIKRMNEGFNHAGKSLSAATQFVMGCTFNPNSKNLD
AQVSRLERKIAAGAQYVMTQPVFDVRVLDEMCRRTQEFGVPVFTGVWPLLSGRQTEFLHN
EVPGILVPDEVRQRMAGTEGEEGSARGLEIAREISKAALERLPGVYLITPFLRYSATVEL
AAFARGL
>A0A182XYW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles stephensi|TrEMBL
MATTNSITENVVHEEGLYTKLDRIFSTPSAPGVAYSLEIAAKDDFDVGLLERLVPQPVFC
SLPWISDDNLRYSDDFLRAPTMQLSAQLRSAHYTVVNHVSCYNITEHQVDGLLASGVQNL
FVVRGDTVQEEQKFQHSASLVHYLRKRQQESTLPPRLTIGVGGYPYGHHQSSSQAQELAY
LREKIDHGVDFLLTQTLYDAGSFFRYRDRCRQAGITIPIIPGIYLPHSYRHLQVMLRLTR
ITLTAEVDAAFAAHADDPPEQFEAFVLDHFAGVLRELLEPNRTSSADAIKLVHFFSFNKF
PLIQKMLQKLDDFFLQ
>A0A8I1UHG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp|TrEMBL
MNAFRPSRHGSRRPRVSFEFFPPKTEEMEVALWDSVRRLEPLGPSFVSVTYGAGGSTRER
THATVKRMVEETGLKPAAHLTCVSASRSEVDEVIRSYWDAGVRHVVALRGDPAGGLGTAY
EPHPDGYHQTSDLIAGLKRIGDFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRAKGIEIPILPGIVPVQNFKQTANFARKTGASVPQWLADRFEGL
EDDVATRRLVAAAVCAEQVLDLIDRGATDLHFYTMNKADLVYAICHLVGLKPEKAAAQAV
AAE
>A0A1C3XZ82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium aethiopicum|TrEMBL
MALKNEARGRNIGISFEFFPPKSEEMEGQLWETVSKLQDWDPDFVSVTYGAGGTTKAPTL
STVTRFLAQTPLATASHLTCVGATKEETHQVIDTFRNAGVTHFVALRGDAPGGAGAPYAP
HPGGYANAAELVAGLKEIGNFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGVSIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGYDD
KPEERAKVAADVAAEQIEDLVRRGIDEFHLYTMNRAPLVSAVLDNLGFSRRATKSAGAAA
>A0A6B2FFU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium 4M9|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRAIARDYWENGIRHIVALRGD
LPPGSGKPDMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNYKQLTKFATMTNVRVPKWMDSMFE
GLDNDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAA
>A0A5K7ZC06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina widdelii|TrEMBL
MEKILRAGHFAFTGELGPPRGSNVAAVREKAKPLVGNVDAVNITDNQTAMVRMSSWAASL
LAIEEGLEPNYQMVCRDRNRLAMQADILGASALGIRNLLCLSGDHQQFGDHPQAKGVFDI
DSTQLIGAVKKMRDEAKFLGGADIDEPPKIFIGGAANPFAEPHEWRVQRLAKKVKAGVDF
IQTQCIYNMERMRQWVKEAVDMGLTEKVYILAGVTPMKSVGMARYMQLKVPGMDVPNEII
KRLQGVDKKKVADEGIKIACEQIEEFKEMKGVAGVHLMAIEWEHKVPEIAERAKVLPRPV
V
>A0A096AHY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella montpellierensis DNF00314|TrEMBL
MTLREKHEQHQFTITVELDPPKSSSAQKTFDEAKRLQGKIDAINIADSPMSNMRMSPIAL
SHLLQSQSNVETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDQPTNGDHPQAKAV
FEVDSMGLLHIASSLNEGHDLAGNPLDAPTNFYIGTTGNPCADDLVSEKEKINKKIDNGA
QFIQTQPIYDLEKAKRFIDSMASLNIPIMLGLIPLKSYKMATYLDTKVPGITISKSILER
VKIGGKEAGLEVAIETLQEIKKIAHGVHIMPLNDIDTVLHLIDNV
>A0A3N0EI35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsaceae bacterium YIM 96095|TrEMBL
MSSLAELLTEPTPARPVITAECPPVDGGGLNAISEHVRRLAPYVDALNATDNAAAHAHAS
NVAVAIALNRLGVEPIMQVACRDKNRLALEADIVGAALHGVTTLCCMTGDDVTAGDEPET
GRVFDMDSPQLIRAANRLAQGRYLSGRPLDPAPPLLIGAVENPGAPPYAYRVRRGLKKAA
AGARFLQLQICYHEDRLTEFTNLAESTGLNRKVALLPTICLVKGAKALRFMNERVPGIAV
PQSVIDLVANASDEREAAYQLALEQAKHALSLPGVRGLHFADFRHDDTLGRIVADLGLPT
VRGAPDSEAIAV
>X8IT25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. ACS2|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHGATHSLFKHHSQVSAL
>A0A212LY53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Sporomusa sp|TrEMBL
MTLIDKLGKSFVFTTELGGINGTDIEGSITKLKEYDGVDAINIHDCPNARLRMNSVMAAA
IIKQVAGVETIPHFTCRDRSLLGTQADLLGAHALGIRYLLPTTGDGPQHGPYQSSAVYDY
NTAKLIELIKSFNQGKDANGEAFTGQTQFAVAATATPGAANLAAETVNMQRKISAGADFF
QTQPVYDPEQAGRFIDKAKSLGKPVLLGLMPLKSLKMAEFVNKNVAGVTVPAQILTEMEQ
GKTGFEIACEFICQIYRQVDGIHIFGMGDVAVTNKVVAFTRELLNRR
>K9THV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillatoria acuminata PCC 6304|TrEMBL
MKQPQNSLSRFRQAVRDGEFLMTAEVMPPKGGNAAHMITMANGLKNRVHAVNVTDGSRAV
LRMSSLAASTILLHQGIEPIYQIACRDRNSIGLQADLLGANALGIQNVLALTGDPVKAGD
HPKAKSVFDMESVRLLKAIAKLNQGFDINDKPLTDSPTDLFAGAAVDPQSKSWSGLKSRF
EKKLEAGAEFFQSQLVCDFDKLDKFMNEIAKGCGKPILVGIFLLKSAKNAEFINRCVPGV
DIPQHIIDRLAKAKDPLREGVAIAAEQVQMARSLCQGVHLMAVKREDLIPEILDLAGIPP
LSSEPMSMDSQTLGDRPEVIRISTPTT
>A0A212LUX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Sporomusa sp|TrEMBL
MTTKPSLREALTDSAQLSVTWELVPGRGAREKAQEHLVKMAELAAKDARINAVTITDNPG
GKSAIAAYAMAVEAKRLGIEPIVHYTTKDKNRNALESELYALDRADIENLLVMTGDYPIQ
GYAGNAKPVFDFDAVHALRMITKMNAGAYTKLPPTHFFAGAVVSPFKSTEAETMAQYYKL
HKKIANGAKFIITQLGYDARKFDELKKYVDMHNLAVPLIGNIFVLSLPVAKMMNKNLIPG
CVVTDSLVARLEEEATQSNKKELQLLRAAKQYAVLKGLQYDGVNIGGHGMGYADIQYIME
KGEELSADWQDIARTEFNHPQDGGFYFFEQDESTKLNTCQPVDRTRTGSNNSSLRLKLMD
VVHETAFDHKAPLYPMNKAIAKYIDKSWLKQPFTIAEYTTKTMTNQCRFCGDCAMHELGF
ICPMSQCPKQQRNGACGGSRDGWCEVYPGKQKCIYVTMYEGFKGHGKEDRMKDKYMPPCN
WDLHRTSSWLNYFNDRDYNTNKE
>A0A8D6B7N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas testosteroni|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPEFCSVTYGAGGSTQAGTFTMVRDIQNE
GVGAASHFSCIGATHEKVRAELNELKAMGVKRIVALRGDLPSGYGLGGEFQYASDLVAFV
RQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VRALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A496A9R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MAIHSRPDNFMEALAHQILVCDGAIGTELRKRIPSHLQCVDACNISTEHAEKVAEIHRAY
IDAGADVIQTNTYQANREALAVHGLAEQVEEINRTGVSLAREAAQETCYVAGSVGQIPFQ
TLDTPIPSTKALRRLFKEQMDALVDEGVDLLVLETFVSPKQAEIATKQALTYGVPVIVEI
SGVSGGTVGAGLDVRVFAQTLEQLGAHAVGINCRGPHDLVEAMELLAPVIKAPIAVQPNA
GNPRVEQGEIAVSYTVEAEVFSDYVGKLVELGANMIGGCCGTTPAYTAKIRQALVGREPV
QREQRIFVLPKITSTSKAPTDNPVQQVFETRQHIVSVEMRANTFPQLRAMLKEAKNLAAI
GVDLFDVTDNSGAAVNIGAIATAYRLQQATQIPTLIHWTTRSRNLISMQSHLLEAEALGI
RGIVALSGDHPKAGPYETASLVPDVRGAVQLMGLIARLNQGELADGSSIGEPCSFYYGGG
FTIAENLQPHVKHLGNKVAHGAKFAYTQPVWTYEDIVRAQQATEHLDIKILYGILPLTSF
RSASYLRDNLGLYIPQFIVDKFRDLGDTAGHELGMRLSLELVQEIRNQDERAIDGIYLIP
PARMNWKNRASVISEIVKTYR
>A6L1E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 / NBRC 14291 / NCTC 11154)|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELAGEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>Q3A7Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophotalea carbinolica (strain DSM 2380 / NBRC 103641 / GraBd1)|TrEMBL
MKRAEKSLMERLEQGVIVGDGAMGTLLYHRGVPLSTCFELLNLQHPETVRQIHRDYLAAG
AQLLETNTFAANRLRLAAIGQEDQVRSINSLGAQLARQAAGSEALVAGAIGPLGRTPGET
ADLAGDERRELFREQMEGLAEGGADLLLLETFASLEELELAVTVASRIGLPIVAQMAFFE
GGRTREGVTADEAARRLVAAGASLVGANCGSGPRDVLAVLRTMAAETDCPLSGFANSGFP
EYVDGRYIYLATPEYFAARGREMVEAGARLIGGCCGTTPEHIRALAAAVADLKPAARCVV
PALPKAATVATEPGPEHRGFLSAWGKRPIITVELDPPRGLDCDKILAGARRLADAGADAI
SLAENPLARIRMGNIALAKQIQDQIGIETIIHVTGRDRNLIGLHSEMMGAHLLGLRNVLA
VTGDPVAVGGEAGASNVFDLNSIGVLQLLSALNNGHTLVGGELGEATRFQAGAAFNPNVS
DMSGQLRRLKKKVAAGARFVQTQPIYSVDVLDAMLACLADIRIPILVGILPLVSERNAEF
LHNEVPGILLPETVRARMRGTRGEEGKRQGLAIARELIEAGRGRVDGFYLMPPFGKVDIA
VALIEVIRG
>A0A6I2I4Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium RIT691|TrEMBL
MSFFHANQREALNQSLAEVEGRINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A6L5H7V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FSL R10-2245|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKDDLRGLLTQYQSAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDISNFVRKANAGADSAITQYFFNADSYFR
FVERVRAAGVMIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDATSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A2E0XKV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MSDFLPQLESQILVCDGGFGTQLRKRVPLHIDCLDACNVEESYQELVRQIHLEYCQSGAD
IIQTNTYGANQRKLELYGFGDRVEEINQAGVELAKHAVAKSKMLGLRHDSREIFVAGSVG
PLESNPFERDLSVSEMQQIFKTQIAALVVAGVDLVILETFTNLDQATVAVKLALEFEVPV
IAQISGVSKGLLRDGTDVRVFAQSLAQLGVSIIGLNCRGPHDLLSATEKLAPVISTPLSV
QPNAGTPRIDQGQLDTTYSVSADLFNEYVQKFIDLGVNIIGGCCGTTPEYIRKIRSSVAG
QPPIQRPTQIFVFPEQPKLPKGIVPPNPIQQIFEHKNRIVSVEMRANTFPQLKAMLNEAQ
RLATVGVDMFDVPDNAGATVNIGAIGTAFRLQQVTNIPTLIHWTTRQRNLISIQSHLLEA
WVLGIQGVIALSGDHPKVGRYETAKVVTDLRGSVQLMALLERLNQGHLIDGSPLGEACNF
YVGGGLTIAPNLIPHLKHLRQKVENGARFVYTQPVYTLDDAEQIYHATRNFGIKVLLGIL
PITSFRSISFLRDNLGMYIPLTVVDRFQSLSSSEDQATYGLEMINDFVHQLGRQNRFTVD
GIYVIPPARINWKRKQAIISQLIRTFRSQV
>A0A7W2FGQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aerococcus urinaeequi|TrEMBL
MTDFQRGNGTSLSFEVFPANTQVGTKKLIQTLNELQDLQPNFISVTCSNNKANIEETTVK
IADYVTNTLRIPTIAHLPAAYLSKQQVSTILGQLEKLGIRHVLALRGDIVEGIPPKRDFS
YASDLVTFIQEQAPYFDISGACYPEIHPDSDNRISDIKHLRKKVEVGCSQLITQLFFDNE
QFYQFKEGCSLAGIDAPILAGIMPIVNRKQALRLIKVSSSQLPKKFLAILEKYEHNPVAL
RDAGLAYAIDQIVDLVTQGVDGIHLYTMNQSDTARQIHQATKSLFQTTELLGV
>A0A2Z3IZH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinisphaera sp. LB1|TrEMBL
MSHDVSHNDFSIELFPPKGPKGEARLEQALESLAELHPAFFSVTFGAGGTTRSGTLDTVK
KAMQITGRPAAPHLSCIEGTKASIGELLDNYKAAGVKRIVALRGDLPDGMDKPGVFHHAN
ELVAFIKQRHGDDFHLEVGAYPEYHPAAPSPAEDVDNFVRKVRAGADSAITQYFFNADAY
FNFCDEVAAKGVDIPIVPGIMPINDFGQISRFSAMCGADIPRWVRQKMESYGDDTASVQA
FSRDLIGRLCERLLAGGAPGLHFYALNKAEPTVTLWHDLKLPGPGAHHAA
>A0A434U8L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1A.F.Ca.ET.072.01.1.1|TrEMBL
MEKAAIRPSSIDASIEMAPSQVIDSPDLPGLFPSGVRVYITDIGLADTPTLVKAARRVAD
LGYTAVPHMAARRLTTRQALETRVKALAEEAGVRDLLIIGGDVATPAGSFSSSFEVLETG
FVDKYGIAEVGVAGHPEGSRDFGDEAAIAALQMKSAWAERTGAKMRVVTQFGFDADKFIA
WADGLALSGVDLPIHLGVAGPAKITTLLKYAALCGVGNSLNFLKKRSASLAALATSHSPE
SFVGPIEHHLRAKPDSAIAQLHVFPFGGIKNTARWLYERGSWQDLEADDRSSIA
>L8N2B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudanabaena biceps PCC 7429|TrEMBL
MIEPPQSVFEKPEPTFNKFRKAIANKEFLITAEVSPPKGSDPTHMLAQTRSLKGRVHAVN
ITDSSRAVMSMSPVAASVLIQQQIGIETICQLACRDRNRIALQGDLFGAAALGITNILAL
TGDPVKAGDYPDARSVFDYESVRLLQLIQKLNQGLDANGKVLPNQGTDFLAGAAVDPQSP
SWSGLQKRFERKINAGAQFFQSQLITDFERLDKFVNQIANQSDKPILAGIFLIKSAKNAI
FLNKFVPGVQIPDRIIDRLAKAKSPLQEGMAIAAEQIQTARQICQGVHIMAIKAERLIPE
ILDRAGIALL
>A0A511Q786|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas aquatilis NBRC 16722|TrEMBL
MTISVNQLEEAQIALKAPLYADVGGHLDVSFEFFPPKTEKMDEQLWEAVRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATRAEIDQVAEDYWAAGVRHIVA
LRGDPPAAGAKFESHPGGYENAAALVAGLKRLHPFEISVAAYPECHPDSVSVAADLDNLK
AKIDAGATRAITQFFHEPETFFRYRDKVAAAGITAEIVPGIMPVTNFASVVRMSKMCGTE
VPAWLARLFDGLEDHPAARQLVAATLAAELSRKLYAGGCKSLHFYTLNKAELSFAICHLL
GVRAKPMQDAAAA
>D8GTX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium ljungdahlii (strain ATCC 55383 / DSM 13528 / PETC)|TrEMBL
MSLLKEAFEKGEFAITAEMAPPKGTDLSHLIECAKKIKGRVQGVNVTDFQSATLKATSLA
TCKVLKDAGLEPVFQITGRDRNRIAIQGELLSAGVFEIENVLALTGDYTATGDHPGAKPV
YDLDSVGILQVASILNGGKDMGGTDLKGKPDFFLGACVTPRYDPLELQVIKMKKKIKAGA
KFFQTQAVYDMETLKKFKEETKAQGVDAKVMVGIIPLKSAGMAKYMNKNVPGIFVPDELI
DRMKNAEDKVQEGIKIAGEFIKAVKESGLCDGVHIMAIGAEENVPLILDEAGL
>A0A373FIH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas testosteroni|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVATRQALYARKPQFCSVTYGAGGSTQSGTFTMVRDIQNE
GVAAASHFSCIGATHDKVRTELNELKAMGIKRIVALRGDLPSGYGLGGEFHYASDLVAFV
RQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYTRFVDE
VRALGIETPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A7C9IFY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kangsaoukella pontilimi|TrEMBL
MAAPTVSFEFFPPQSLEASFRLWDTMNALAHLDPSFVSVTYGAGGTTRDLTHDAVKTIGK
HAGLNVAAHLTCVDATRDETLEIARSYAEAGVTKIVALRGDPPKGAERFVPHPDGFADST
ELVAALAETGLFDEILVGAYPDPHPEASDPDADVRWLKRKIDAGATGAITQFFFEAETFF
RFRDRAVDAGISAPILPGILPIQSWEGVQKFAARCGAHIPETLAQAFEAATRDDRVELLA
TAVATELCTDLIEGGVEHLHFYTLNRPDLTRDVAHALGLAPAATLQKVA
>A0A8E2UHL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola|TrEMBL
MDPDTPSLAGTITDAYSLEVSAKHIAGLAAAAPRITRGATIAIPYLPNQDDDARLAAARM
VRALGFQPMPHLSARRIASREQLHAFVSRAVDDAGVERCLVIAGDPPAPLGPFSDSLSLI
DTGVFERCGIRTIAVAGHPEGHPSMPAADRWEVLQRKCRSITERGMAPLIVTQFAFDADI
VLTWLQALRAHGIAHPVRVGVPGPAGVAVLARYAASCGVGACASMLSKYGISLGKLLGTA
GPDRFVERLATGLTDAHGEVRMHFYPFGGIAQTVAWVEQYRSLTARGRAD
>A0A363U7M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MPIFTPGRRWQPAYSPFKEEPLSHKLMEDFEYIIKGPLFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGSTPEHCYVDKTRPCIWYKIYERAHNMGREEKLLEVLPPLDWEKVGTETW
KDVTTCIRKNGTGKVLRSLVLDQGENRYKTWDLIFRTVRQPDWWQGDDKYHAPAYAEPVS
DLERALKAGEFVVACEIAPPLSMSTKKLIENINLVKPYVTAINFTDNASATPRMTSWACS
KFAVENGAEPVMQIAARDRTRASLQGEILGATAFGVRNVLCVTGDSPVLAPQPRGRMDIN
DLDAIQMIWILRRMRDEGHYLDGREIKFPPRFFLGAAASPFASDPKFQALREHKKVNAGA
QFFQTNLVYDVERMQIWLNEIAKRNILDKVYIMIGITPLKSAKMTHYMNEVPGVYVPDEI
VKRMDDAQAKGGPEGAKEEGVRIALEIIEKIKALRGQGIHGLHIMPVGWEDVVPRIVTEA
NLLKPGTAVPEKEAEPLPA
>A0A4R4BB48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASVLLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESIKRATLNVMPVIKKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGILISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2T0EXC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKYLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7X7TSN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotogaceae bacterium|TrEMBL
MKVIDKIKEGQVLSIEILPPNRGQNIEEIYSALDQLMQYPINFINVTRHAPEMTYVELNE
RIVKVPKVKRPGTVGITAALMRRYNVDVVPHVLCYGMNKYQIEDMLIDLNLIGVENLFVI
RGEYENQSAEVEKESYRHASELVKQISNMNKCEYLYPCENAHPTNFCIGVAGYPEKHFES
PNLEEDMRHLKEKVDMDAHYIITQMVFDANVYKRFVEMARALSINVPIIPGIKPIVSLKS
IYSIPRKFFVNIPESFVREMQEAKTEKEEFRIGVDYTARLVEELLNYGAPGIHVFTMGRG
QSTKAVFERVFGK
>A0A1M6UTP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia thermophila|TrEMBL
MSTSAAALRARFAERPLICDGATGTMLHAAGNSLDQSLPALSLTDPQLVRAVHDSYVDAG
VDVIQTNTFGASRLRLSEYGLGDQVEQINRAAVRIARDAAQARHGILVAGSVAPAVSVHQ
RRRTPPQARIDALTEQLSVLADAGVDLIFLETFGYLDELLEAVEVAVAAVDVPVIAQATF
SHDAHTLSGHTPREVAEALTGMPVAAIGTNCTIGPQRVLAVVRELREHTDLPLTAQPNAG
LPRRTGRARFEYDIDSEYFVRYVRQLLDAGTSLVGGCCGTTPTQLAAVVEMAAEHRARTA
VAAAPRTEPEPAAADTAPAFAGPDRLVAVELTTDTAADVEQAARLAAELTRAGAAMICIG
AGDGLRARISPADLALNLHQRLGVEVTATVTTWDRTIMALQADLLGAHALGLRRIVCETG
SPPLLGDYPHVDGVWDVDSIGLVELVARLNEGTDIHGFPLPSRTAFEIGARINPGSRDLA
RAAARARDKIAAGAQFLITRPVYDAADLERLLEAIGGDLPPLLVAVRPLTDFAEAEYLAH
EVPDTHIPERVLTALEKAGPAAAEVGLELAAELVAAVTPLAKGLVITPTRDAVRAVERLV
TS
>A0A2B0LE24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTLKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKSHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1G8KWF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus hippei DSM 8344|TrEMBL
MENKFKESLLDKNTLSVTWELVPGRGANEKAQQTAIASAEQAAKGGRVHALTITDNPGGN
PAILADYLGMEIIKLGIEPLVHFTCKDKNRNQMESQLYALDRANVRNLLVMTGDYTYSGF
KGRPKPVFDLDPSNTLQLITEMNKGLEVPGMKGPTYHAPSDFFAGAAVSPFKSTEAELMI
QYYKMKKKIQGGAQFIVTQLGYDARKCHEVLQFLKVNNLDVPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNTEKTAEDKGVGQRMLRAAKMYAFMKGMGFAGVHIGGHNLKYEQ
VEYIIDKGEELSPNWQDYIKEFDYPQNNGFYYFEKDEKTGLNTDRPTNRANRPLDAPAGA
MNSMMRGMHSLMFTPDKKLFPVLRSMYHAAEGKKKAEKRLHAVEHIAKVVMLDCKDCGDC
AILDIGYLCPMSQCPKNQRNGACGGSLDGWCEVFPKEKKCVWVRAYARLKKYGEEATLDV
PPVPPANWDLYQTSSWSNFYLGKDHSAPVLGIKRPESKIKK
>A0A524PNH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
FDELNLTQPALVAEVHRDYINAGAQIIETNTFGANRFKLGAHGLENQVKEINQAAVQLAQ
RAVEASFKQILIAGSVGPLGVRLAPFGRVKPDQAFAAYREQIAALAEAGCDLLMIETQTD
LHEVAEAVRAARSVCQLPIVATLTFTRDDRTLLGDTPHQVARMLNQLGVEVLGANCSGGP
AQLLRILTLMRRAVPQARLAVMPNAGWPERVAGRIMYTATADYFGEYALSFCQTGAVFIG
GCCGTTPEHIAAMRQALDSDDQPCAELEPLEVEDTSNLSAASSEPPSQLALALAQNRFVL
SVEMDPPRGFSSHKLLAGASLLAEAGVDVINVADSPMARMRMSPWAVCQLIQAQIGLETV
LHFPTRGRNLLRVQGDLLAAHALGVRNVFVVMGDPTAIGDYPDAMDDYDLVPTGLIKLIQ
HGFNKGVDHAGSDIGGATSFFIGCALNLCAKDTEAEMSLLQKKLAAGADFALTQPVYHPE
HASKFLETYQARYGELKLPILVGVLPLYSARHAAFLHNEIPGIQIPEAILERIRAADDRA
PEVGVQVAIELLESLSGLVQGAYLMPPFGRYDMAAEIIEAIRGKS
>A0A4U3BNV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
KHIGAVTTTDMEREFILLEQAGALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVA
QLALHEAGTTQNGNDVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAY
PNAGLPNYVEGRYVYEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITP
VIEKETIQRPKVVHTHEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKR
AGADAITLADNSLASPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGM
EEVLALTGDPARVGDFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAF
NPHVRHLKAAVKRMERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSK
RNADFLHFEVPGITLPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPF
LKYEITEHLVKYVREKQEVKEGIN
>A0A7Y4RH88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MDFLEQLSLGTILADGAMGTMLHARGVGFDKCFDELNLTNPAAVADIHREYIEAGAQLII
TNTFGANRFKLKKHGLEDDVVEINRAGVELAKRAVAASFKDVLVAGDIGPLGVRIAPYGR
VKPEEARAAFAEQVKALADAGAELIVIETMSDLYEIQEAIKAAKEVSKLPVVASVTFTRD
DRTLLGDDPMKVARKLRDAGADVIGVNCSGGPSQLLRILKQMKQAVSDGKFWVKPNAGWP
EQVGGRIMYPADADYFGDYALAFREAGASIVGGCCGTTPQHITAMKKAFESTPVLFTDSI
TVLTDDESMDEPAEQPTQLAQKLSSGKFSVCVEMDPPRGLSTHKLLAGASLLADAGADVI
NVADSPMARMRMSAWAVCDLVQRKVGVETTLHFPTRGRNLLRVQGDLLAAHALGIRNVFV
VMGDPTSIGDYPEAMDNYDLVPSGLIKLIKQGFNMGVDHSGTSIGQPTNFFVGAALNLCP
QDVDNEVKNLHRKVKAGVDFFLTQPIYRMDDGPKLLEAYEAKHGKFSKPILAGILPIVSS
RHANFLHHEVPGIFIPDEARTRIESAGEDGAKVGVELAVELIQNIKPWASGIYIMPQFHR
YDMVAEIIEAVK
>A0A7Y5F290|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MTPPEYKSDGRLEKVLRAGLFAVTAELNPPDSADPQEVYDAAVVLSEVCDAINATDASGA
NCHMSSVSICALLTRAGYSPVFQVSCRDRNRIAMQGDVLGAAAMGVSNVLCLTGDDVTAG
DQPQAKRVFDFDSIQLLRTIKIMRDHGMFLSGRKLTVHPRLFLGAAENPFAPPFDWRPLR
LAKKVEAGADFIQTQYCFDVPRLKEFMSRVVDLGLHEKVFILVGVGPLRSEKVAEFMRTK
VPGVHIPDEVVERMRKTPKEKKVAEGKKICVEIIQQVREIPGVAGIHVMAYRQEELTAEI
IQDAGLLPRPMRLGAEKHEPARPRHRGQRGVKSDT
>A0A4Y8TC20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVAEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNATPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7X3L6S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. R-28-1W-6|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVGVPTAPHLSCVGDSKDELRSLLSQYKNSGIRRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKAKAGANSAITQYFFSADCYFY
FVERVRKLGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDLESIQAFG
EQVVTEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1M6Q947|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia thermophila|TrEMBL
MPEPEVLDPPGALRERLAAGSGEFLFFAVTPPRLATPPEQAQQIADVTMDRLRPLDLDGL
LLYDIDDESDRTDQERPFPFLPTMDPADFLERHLTSWPTPAIVYRVVGKHAEPELTRWLS
AQDPDRVLSVFVGASSSDQPVATSLRRAQQLRAAVAPHLGLGGVAIPERHTRRGDEHARL
LAKQAAGCSFFVTQIVHDVGAAKNLVSDYVHACAEREVAPAPVVFTLTVVGSPKTLEFLQ
WLGVDVPRWMRNDLLRSEDLLAESFAQARATALDLVAYCRRLGVPFGVNVESISNRRAEI
DAAVELAATLGGELRRPLGRRRAAITADEPA
>A0A2S7XLI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliivibrio sifiae|TrEMBL
MAYSHASHLESLNQNIAELDGNINVSFEFFPPSSEKMEETLWNSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLIAAPHLTCIDASRSELIDIANDYWANGIKDIVALRGD
IPAGGGTPDMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQASRFAKMNNVKIPGWMAQQFE
GLDDDPVTRQMVGASHAIDMTRILSREGVKDFHFYTLNRAEHTYALCHTLGVRPKG
>R5GN24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:786|TrEMBL
MKSNEPFLSMELSQHSALLPGINLASALPQNVGAISDIPCRTAVIISADGTGNNSNALSL
CRENGVETLYLRVNSPARFAAAERILAGVSGEFRVIAEIPAVSRINELHSVRSLTENGVE
ALITRPLFSCEEYHDFMERAALAGITAPISAGVMVLTQESQAERLINAGTALPEKLLRFI
VKYRTSPEALRDAGIAFANEQIVTLLSGGADRIHFYGVDSDYIAGKISALVSGILV
>A0A0Q7Z386|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. Root1497|TrEMBL
MTTNLNSLAEAHRAAASPLFAGLAGDIGISFEFFPPKTDKMGETLWDSIRTLEPLGPRFV
SVTYGAGGSTRERTHATVARIVQETGIPAAAHLTCVDASRDEIAEVAQAYWDAGIRHVVA
LRGDPPVKGESFRAHPDGYGCAADLVSGLLEIAPFEISVAANPEMHPEALSPQADLDNLK
RKLDAGATRAMTQFFFEPDTFFRFRDAAAAAGITAPILPGIMPVSNFAAIQRMSAMCGTD
VPRWLASLFEGLDDLPAARQLVAATTAAELCRRLYAGGVRDFHFYTLNRAELSYAICHML
GVRPAAPATEKAA
>A0A7V2PG77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKSNSKLEKILEGGHFAITGELGPPASANPEVIRKKAKYLRGNVDAVNVTDGQTAVARMA
SWAACLLGKEEGLEPTVQMTCRDRNRIALQMDVLGIAALGINNLLCLTGDHQVFGNHPTA
KGVYDLDSIQLIKMVKDMRDEKKFQCGDDMDVEPRLFIGAAANPFADPFEFRVVRLANKV
AAGADFIQTQIIYNVEKFAQWMEAVRDRGLDRKVKILAGVAPIKSVGAARYMQTKVPGMD
VPEAVIERLKGVPKEDVPKEGIRQCVDIINQIREIKGVAGIHLMAIEWEEVVPEIVEQAG
LLPRPQVYQA
>A0A7C2BI85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MVKLRFEPLAFREVDGLEGPVLARPLGAPSPLEARLAAGEFVIASEVSPPRRARLTSFIR
RARRLSRFAVALTVTNNHAARPRLESLVAAYVLRLHGIDPIWVVNTRDRNRLAIRSQILA
AGVLGVQNVLCVKGDPIEKGSDPEARAVHDLSTVELIRLFAQQKAEGHHFFVGGAVDVTS
GPVDKAFRLARRRVEAGADFLQTQPVFELGPIAELAGRLRRLEDRRPYLIAGLMPVLDPE
DVGRVERNLGIPVPASVREALGRARDPREAGFKLLADLVAGLRRIDGVHGVNVMLFDQTD
HMVEGILACLGARAEAAS
>A0A3N5XX05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MLSISLLTADTLFIMLNDHIYNVKGFCYFTRPGEKVSLLSFPPYQQASIIKRNMKGFLDS
LQERVLVCDGAMGTRLYDLGISPQHCYEYLNIEQPRIIEDLHRGYLDAGADIIETNTFAA
NSSKLAKYNYGKLAPAINEAAAKIARMAAGQTAYVAGSIGPLDKSSADQQLSDQQIYDIY
KEQVMALAEGGVDVFILETFSNLEHIKIALSACKKETSLPVIAQMIFLDGLRTGYGNSIQ
SIVDALTAGGADVIGTNCGNGPSALKDVINKLVQITDKYISALPNAGYPQVVDGRSMYLT
SPEYFAIHAQELVNSGVNIIGGCCGTTPEHIRLIAGKLKNRKPAQRPERKAETEMVFVQA
PAFYEKKVGGAANVIVELLPPKDADIEKLIDTAAMLKGSGAQVLSFPENPLAQVRMSSIA
AAGLIKRTTGTEAIFHYTCRDRNLIGLQSDLLGAYALGLRYMLAVTGDAVSLGNNPEASP
VYDVDSIKLVNLISNMK
>A0A6L5K8M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MVSSFKDVLNSGKFVITSEVAPPKGTNLEKVLHHIELLKDKVDAINVTDHQSSVMRFPSI
GGCLAIKERGGEPILQMTCRDRNRLALQAELLFASSRGINNVLCLTGDAVLVGDHKEAKG
VFDLDSLQLLKTIRLMESGQDLGGNNLDGAVEFCAGATVTPEAEPLEPQLIKFEKKVEAG
AEFFQTQGIYDLDNFAKFMEHARQFPVKILAGIILLSSARMAKFMTANVPGIFVPQNMID
ELAAAPKEEMLNKGIEIAGRMIAALKKDSVCDGVHIMAIGKEEVVPDILAAAGL
>A0A3B9HCA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MPDNTSFNESLEKGTILGDGAMGTLLYQMAMKHDTKPVEELCLSRPDSVRLAHIEYIRSG
ATMIQTNTFAANRNKLASYGMTDSTSLINKAGIEIAKEARRLTGQQVWIAGSVGPIGRHL
EPIGTVSLVSARKFFQEQVDALAEGGADLIILETFSDLREVELAATAATSACLPFIAQMA
FGHDGLTSLGHSPGEAAAAMESMGAAVVGCNCSVGAAPMVSTVSQMLSRVSIPISAQPNA
GFPTMHQGRTVFGSSPEYMASQATRLVDAGASLVGGCCGTSPTHIAAIRDSIPTRARPKK
DQLPSRRITISTREPFLSSDNEIPEPSTFSTKLKEHKKVITMEVDPPRGFRASSELSQLE
QIRNAGVLDAINIADNPRAQRRMSPLAMATLVQNRLGMETIMHLALRHRNYASLHSDLIG
AHALGIQNIFTVMGDKPRFDNYVNPYTPSNLTTTGALNLMKSFNGGLDLSGEPLESPTAF
LKGASFNPTAKDPDREFRLLESKLEAGADFLLTQPVYDSAAVQKTAQKFGGFPIPVLIGI
LPLRSKRNAEFLQNEVPGISIPPEIMEAISSSSDPRRTGMDISRRIVTELSDTVSGVYYM
APFRRYESIIEFTESLDFA
>A0A2K5L7U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cercocebus atys|TrEMBL
MDHRKARVLPAGHYCPSLGIWASQAGSVRFSVAPSISRNLAMVNEARGNGSLNPCLEGSA
SSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEESSPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDALELLNRPTQNERETEAP
>A0A3D5MXV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp|TrEMBL
VYIGASIGPIRNEYMEENNDEILEEYKFIVDCFIEKGIDIFIFETFSSYHHLDKISEYIK
KKNKNNFILTQFAFKPDGYTRDGFSVDNIFENVKNNKYIDAYGMNCGSGPAHLFELVRKI
KISKGDIVSILPNAGFPEIIHERTVYPNNPIYFAKRINDIRMQGAVILGGCCGTNPLYIR
EIKKILDKKDFREVKKNEETNKKIDSSDNVSNTFKNKLENNEFVIAVELTAPVDTEVTKL
INSADICKKNEIDLVTVPDSPMSRVRADSVLISAKIKREIGIEAMPHVCCRDKNTNAIRS
SLIGAHIEDIRNVLAITGDPVSDASKIKTKSVFNLNSFKLINLINTMNTDVFFNNGMLIG
GALNPNVRNKHIEYERMKKKIECGANFFLTQPIYDEEAIEFIKEIKEKTNTKILGGILPI
VSYRNAVFLNNELPGVNVPACIVNKFKEGMSKEEAQKVGMDIAVDIGRKLKDICDGLYFI
VPFNRVDMIMEIVKNIRE
>A0A7C4END1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MFSKEWFIYVFGRWVVVSGIAGAIVQYFFADMLHIHTIPAFLLNQFCLACVFWYVDRLIF
KRHFKENLLEFFRFPRIRHAFSLKDQCTMLTREFSDFRNAVSGNEENPQQWLHAFVDLVH
AVEMTELLLREHSINIDAEIERVREENRKKGLYEQDPAKPKPHRTRQCQSDFLTAISQKT
IIADGAMGTYLLHKLGNKETCLEYLNCINPDLVYSVHAEYCAAGAHLIETNTFGANRIKL
ARYGLAEKAAEINREGARIARKAAGSTVFVAGSVGPLGCLLSPYGTLSLADAHAAFREQI
EALAEGGVDLIIIETMTSLLEAREAVLVCRQICDLPIVCQMSFTHEGFTLQGDPLGDSLV
QLRSLGAAVVGMNCTIGPQEMLDLVQQIPADLQGILAVQPNAGLPAHKNGAITYPSSPEY
FALYAPQFQQYGACLIGGCCGTTPDHIRAIAGALQQRPPAAQPRKKHSEPPSVALPAEPQ
KTTIPLYVEQQPFITVEVSPPKTIHFQEILNHIQAYKNAGADAINVTENPMARMHMSSLA
FCALIKRQSDIKIFLHVTTRDKNLLALQSDLLGAAALGVDGVVALKGDPASIGDIPYATS
VFDVSTTGLIKIIR
>A0A7Z7ELJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis pv. eucalyptorum|TrEMBL
MIPTDTPSGASTITDAYSLEVSVKDIGALTNAAPGILPGCAMFIPYLPGQTEAARLAAAQ
MVRRLGFEPVPHLSARRIGSLEELQAFIARLVGEADVTGCLVIAGDPSTPKGPFADSVSL
IETGVFERSGIRTIGVAGHPEGHPIMRTTEQWDVLQRKCRSIQERGMAPLIVTQFGFDAD
IVMTWLEALRARGMTHPVRVGVPGPASVGTLARYAASCGVGACASVLSNYGVSIGKLFGN
AGPDRFVDHLVGRLTEAHGDVRLHLYPFGGIAQSVEWVAHYRSCKASQDRVSSVAAD
>A0A7C1WG68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MLVDKIKNRESGIILYGITPPKKGTSSEEIEEISSRQIQRLQSLKVDGLILYDIQDEKSR
ISEERPFPFMETLDSFSYSKEYLYSLPIPKIIYRSVGKYTKSELSQFLVNASSKDYLTVF
VGASSKSQAVTLSMNDAYKLKAETNSDLLLGGVTIPERHQSKGDEHIRVFNKIAQGCTFF
VSQGVYDVNASKNFLSEYYYYGQEHDIPLVPIVFTLTPCGSLKTLQFMKWLGISIPKWLE
NELIHSSDILQKSVSFSEQSWLELKSFADEKGIPIGCNIESVAIRKVKVDASIELLRRVS
K
>A0A855N164|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter hyointestinalis subsp. hyointestinalis|TrEMBL
MLKDKIKENKPGILLYGITPPKINLSKDEAYQIAKKQLERLENTGIDGLVIYDLQDESAR
NDEKRTFEFCGTIKPEIYHKEFLKLSYPAVIYKAVGNYTKEEFANFLNTSNNDMLSVFVG
ASSKNDLLKFNLNEAYKLKKEQGGNVTVGGICIPERHEKKGDEDLRVASKIIKGCEFFIT
QAVYNIENAKRFLDDYANLGIKKVPIIFTFTPCGSHKTLEFMRWLGISVSKQFEDRLFES
DDPLSASVGLSLDMFEFLYKYGRAKGVSVGANVESISTRKVEIEASINLLRGIKNIIQNE
KECNLEELIQSASKFYE
>A0A1M5TKW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis glycolicus DSM 9705|TrEMBL
MAETVTGSRLEKVLKSGHQAVTSECGPPRSSDASHIITKGQLIKDHVDSINVTDNQTSVT
RLCSLAACVHLKLQGLDPVLQMVVRDRNRIALQSDILGAASFGINNVLCLSGDHQRFGDH
PQAQNVFDLDSMQLVQTVRYMRDEGKFLSGDEIKQPPSMFVGAAANPFGDPFKIRVPRLA
KKVACGAEFIQTQCIYNLDKFEKWMEGVRERGLHEKVYILAGITPMRSVGMARYLQKNVP
GMDVPDELIERMKGVEKKKQADEGITIAVETIQRLKECKGVAGFHVMAIEWEEKVPEIVE
RSGLYPRPKID
>A0A432SB14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sp|TrEMBL
MFDTLIEKLNSSTYITLETTPGHSPIFAPIVEKIAKLELDKYVDGFSTTDNPLAKLKYNA
LFAAKMLQDRFNKPVIATMSMRDRNKIALQSDLLGSNEVDICAILALTGDPATMSDQPRT
KGVFEGDSTLLLDIISAFNAGMDYAGKPLKHKPKHISAFAVVNAYAKNPKTLQKKIQKKI
KHGAIGIITQPVYDLENAKLLLELRDNANAECCPDKKKAELIFGVFPITKLRTAQFLSAH
VPGINVPDIWLEKLRLAHEKGPEEEYKVGFDLSKTLFDDLKALHPKIHLMTANQFEVARD
ILI
>A0A164QVY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sistotremastrum niveocremeum HHB9708|TrEMBL
MKLVDKISLFTPANPFFTFEFFPPRTDQGFQKLIARITRLSRLNPLAVSVTWGAGGATIN
RSLDLAWAAQREQRLETILHLTCTNMVQGLIDDVLKNAKECGIQNILALRGDPPRGEEYW
KPTDARFQHAADLVSYIRSSPLYSDYFCIGVAAYPEGHSDKLLEEDEELAYLKQKVDAGA
DYIMTQHFYDVDAFLEWVKKVRQKGIRVPIIPGIMPIQTYSSFLRLTKLCGTEAPPHVMD
ALEPIKHDDQRVKDFGVALAVEMIRKINASSEISGFHFCTLNLERSIVLILEQLGWTGEH
ASTTNRLITGASQVEVEDSSLNSNFRITPSEALDTAASTLAGKSSRGLAQEVGKGELNSE
ATWDEFPNGRFGDAKSPAFGIGQDPWNPSSSVLTGPDREWGSPKSTEDLTHLFLQYLHSE
ISSTPFSSNPLSLETKKILPQLVALNGAARWTVGSQPAVDSALSTDEVVGWGPPGGYVFQ
KSFVEFFTTHDDLLEIVSKLEKIDGDWFTFYAADSEDNFTSNVDAQARNAVTWGIFPGHE
VTQSTIIDKESFISWKEEAFEIWHQWALTYPPDCPERRILDEVWRTRWLVTIIHHDFKTP
DGLWKLLLDNRDSNKTEDPNRVTK
>A0A0P7WKC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacteraceae bacterium HL-111|TrEMBL
MPPTLDELHEHRTALDTPLFSGLPGDVDVSFEFFPPKTEKMEAQLWDAVQQLKVLAPEFV
SVTYGAGGSTRERTHATVSRIIREAGLPAAAHLTCVGASKAEIREVAEQYWEAGVRRIVA
LRGDAGEPGAPFTPHPDGYAGAAELVAGLKEIADFDISVAAYPETHPDADCPQACIDHLK
RKLDAGASRAITQFFFSPETFFRYRDALAASGIDKPVIPGILPVTNVAQARKFAGACGAT
IPGWMDGLFEGLDEKPAARQLVAATVAAELCRRLYAGGVRNFHFYTLNRPDLAYAICHML
GKRPVGEAAAAPAAAVQGEAA
>A0A523UPR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
TDVSELVHHIDVLKDKVDAINVTDHQSSVMRFPSLGGCLLVQEHGGEPILQITCRDRNCL
AIQADLLLAYSRGIRNVLCLTGDSVDVGDHKEAKPVFDLDSVQLGQMIRIMESGKDLGGN
ELKGAPQFCLGASVHPEADFVEPQLIKFEKKVAAGMQFFQTQGIFSLESLRRFMQYASQF
NVKILAGIIVLASARMARYMNENVPGIIVPQDAIDELASMEKGKGLQKGIEIAVRLIKTI
REESLCHGVHIMAVGNEKIVPDILEAAQAVGVQS
>A0A2E8UTG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSEKYQQLRDVLESGRFAITAEIPAPVSASSVEMEEKIKILKGSVHAINVTDNPGATAHM
SSLAGSAIVRNQGIDPILQITCRDRNRLAIQSDLMGASALDINNVLTLAGDPVKNGDQKD
AKAVFDINSKTILSIMDVMNTEGKTMSGKELQTKSNFFPGGA
>A0A366KUC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter miscanthi|TrEMBL
MKITDHIKNAKGKTLFSFELLPPVKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QANGLLQKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHCYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMSTDFKYLKKKVDAGAEFIVTQMFFDNQKYFDFVKKCRENDINIPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNNEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKKIAKAIF
>A0A4U6NFC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. NamB2|TrEMBL
MPPPTYPALSYELYPPRNAEAEDSLWTTIRRLEATRPDFVSVTYGAAGSNQETAVDLLRR
LLTETSLRPLAHLTCVGSSRGELEAIVDRLIGGGVRGILALRGDAPDGETHPGELQHADE
LVRLIRDVEAKRSAQLAAGRVSVGVAAYATRHPDSPSVEQDIQVLLAKEGAGADFAITQV
YFRPDDYSGLVSRARDAGVTIPIIPGVVPMTSTRRLTKLSELAGIGVDEALWSRLEGART
DAERRRIGVAATVDLARTALADGAPGIHLYTFNEHSAALDVLDALDLKRPPEAGLAASM
>A0A291RHX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia terpenica|TrEMBL
MSFDNARGRSTPGRLSRTPQVSGTPSVVGRLGPRPDGTIPFSVEFNPPRDAANEARLWRA
AREFERMHPAFVSMTYGAGGSTRDRTARVTGQLARETTLLTVAHLTAVGHSVAELRSIMG
TYADSGIRNLLVLRGDPPGDPLGEWQRHPEGLEYAEELVRLVRGLGDFHVGVASFPQGHH
RSPDLDHDTAHLCAKLRAGAEYSITQMFFDVDDYLRLRDRVVACDPIEGAKPIIPELMPI
TSLRTVQRAEELSGRPLPTPLRERLERAGGADPDANRAAVREVGIEIATEIAQRLIDEGA
PCLHFITLNFAKATSEVLTNLGYTVTAAPVGA
>A0A316WUJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium viscerum|TrEMBL
MKITEHIKKANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINNLGRGKYLHNEEQICDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFYDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINAVENAKNNEAVKQIGIEWAITQCKELLDFGVPVL
HFYSMGKSDNIKKIAGELF
>A0A1F8ZW03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_43_22|TrEMBL
MRLKEALTKEKFVVTSEVQAPLDEEPQELIKRLQLVRGRVDGIAVPELEVEGIVGDSIKI
CELLKQNRFESIYQTTTRDKNRPQLQKDLISAHQAGIENLLVFTEDYRITGDSLQEMMFF
HVDVGKLSSVLDHLKEGSTIDGKELSLKAEFTVGSGIESKWGKNIPDLEMREMEEITKMG
TGYFLTTPVFDLVTFEKFMKPVRSFGVPVIAEVIILRTAGMAQFLNRHLQSGLVPDWIIK
KLAKATDRQKASIEIFTEIVTGLKDLCQGIHIITLGAEDKLRLFLDAAELK
>A0A523UCK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAPSFREILNSGNFVVTSEIGPPKGTNIEKMLHHIDLLKDKVAALNVTDHQSSVMRFPSL
GGCLAIKERGGDPILQMTCRDRNRLALQAELLIAYTRGIRNVLCLTGDAVPVGDHKEAKG
VFDLDSVQLLRAIRQMESGKDLGGNDLDGAVEFCAGAIVTPEARPIEPQLIKFEKKVESG
AEFFQTQAVYDLDNFAEFMQYARKFPVKILAGIVLLVSARMAKYMNENVPGIFVPQHLID
ELASAPKGEAVNRGIEIAGQMIATLKKESLCDGVHIMAIGREELVPEIMEASGLSSSKPQ
T
>A0A523V0P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MHITELIRQKKFVITCEIDSPKGVNSETFLDKVDEVKNSVHAISISDNLRAVMRCSALAM
CHLLKTRDIEPIMELNTRDRNRLALQSDLLAAATFGVENIIISSGYDVSLGDHRDASPVH
DLDTVSLVKAARDLNDERDFAGHSLDGPSNFCIGVLAEIGLKPDATQMDKLKRGVDAGAD
FIVTQAMYDTAVLEEFLGSVGQFRLPVIVGHVMLKSASSASFLNSNAPGISIPERIIKQL
EGLSREALFGTSQQITVEFIESAKSLCQGVHLVPMGWERFIPHIVEAVGS
>A0A1F7RV88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Schekmanbacteria bacterium RBG_16_38_11|TrEMBL
MSLRELFEKRKFVLTAEIEPPKGTDVSKFLETAESLKGKVDGINVTDQQSAVMRLGSLAA
CHLLRDKGFEVIYQITCRDRNRIALQSDLLSAAVLGIENVLILTGDHPCLGDHPDAKAVF
DLDSVQLLKVAKSLGEGHDIAGNELKKAPKLFLGAALNPCADPLEPEFIKTEKKVKAGAS
FFQTQAVYDTERFKQFTENIKHLNVFIMAGIVLLKSAKMARYMNEKIAGVNIPDPIIERI
EKADDKRKESIEISVSIIKEIQKFCHGIHFMALGWEELIPEIITRLNLTK
>E6MVW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis serogroup B / serotype 15 (strain H44/76)|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A4S2AZU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. NM69_E16B|TrEMBL
MRVIDLINSNERTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIHWLKKKMEMGAEYAVTQLFYDNRKYFDFVKRARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQAGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIREVAKQIY
>A0A209BSB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CS159|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSAAWDTDVAHFVD
KCRAGADYAITQMFFQPDSYFRLRDRVAAAGCDTPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A4Y9IRS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dysgonomonas mossii|TrEMBL
MTITELINKSDKTAFSFEILPPLKGNNVEKVYNIIDKLIEFDPQYINITTHHSEYLDQQM
PDGTVKRVNIRKRPGSVAIAASIQHKYNVTAVPHMICKGFSQEETEYALIDLNFLHVQNL
LLLRGDTKRLAPEQIYPNRNEYATDLQLQVNNFNEGIAADGSLFEKNATPFSYGMACYPE
VHEDAVSAESDIFYMKQKADNGAEYFVTQMFFDNQKYFSFVEKCREAGITQPIIPGVKPI
VLMSQLEVLPRIFRSSIPEELAVELRKCKTDDDAKEVGIEWGIKQSKELIEYGVPSIHFY
SLLATESVRRIAKEIY
>A0A523QTK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSIVELIKQGKFVVTAEIGPPKGVDIQEMLETAEVMRGRVDAINATDQQSSAMRLGSLAT
CCILKQKGLEPVFQVTCRDRNRIALQSDLLSASVLGIENVLCLTGDHVSLGDHPQAKPVF
DLDSVSLLQAAKEK
>A5L0N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrionales bacterium (strain SWAT-3)|TrEMBL
MGYTHAIHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPPGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A086ST04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acremonium chrysogenum (strain ATCC 11550 / CBS 779.69 / DSM 880 / IAM 14645 / JCM 23072 / IMI 49137)|TrEMBL
MEKITDKIAALPADGTYFSLEFFPPKTEMGFNNLRDRLHRMERALRPLFVNVTWGAGGST
AAKSIELAELCQKEIGITTCLHLTCTNMSRRLVDKALEDAKALGIRNILALRGDPPRDEE
YRIESDETDGGGGGEELNWGADLVRYIRKKYGDYFCIGVAAYPEGHAELSHPQNQSLEHD
LPYLVDKVQAGADFIMTQLFFDIDAYDKFEATLREHPSGAFRTIPILPGLMPIQSFQMIK
RTTKLSHARMPEDILARLTAVKGDDEKVKMVGVDIVSELIEKIKKIKGRTPGPKGFHFYT
LNLEKAVAFIVERTGLIPDLPNDEEAIIDDAGAAPGPAVHINGETAADRARRPSRSRSAR
RLSSVGSDPHNRVIVSDRRPSHPEWEATGREAGVRAEAVNTRANTLAISEGEGVLGREAT
WDDFPNGRFGDSRSPAFGEIDGYGVSLHMSPAHAIKLWGHPKTVKDISDLFVRHIQGELA
AIPWSEEELLAESSAITPHLAQLNSKGWWTVASQPAVNSTRSADPTFGWGPPNGFVFQKA
FVEFFLPSADWKVLLEKLRAVGGESVCFYAANAKGDFVSSDSSGGVNSPTANVSTNAVTW
GVFPSKEITTPTIIEEVSFRAWSEEAFGIWGEWSRVYGRGSESEKLLRGIREDYWLVNVI
HHEYIDKEALWRLLLS
>A0A523V6K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKTRSNLERVLEAGQFAVTGELGPPQSADSQVIRRKAKILGGHVDAVNVTDGQTAVVRMA
SWAASLIGKEEGLDHIVQMTCRDRNRIALQMDVLGIAALGINNILCLTGDHQKFGNHPMA
RGVYDVDSIQLVNIVRDMRDEKKFQCGDEMAVEPCLFIGAAANPFADPFEFRVTRLAKKI
AAGADFIQTQIIYNVDKFAEWMEGVRDRGLHERVKILAGVAPIKSVGAARYMKARVPGMD
VPDSVIARLQGVPKDQVSREGIKLCVDIISQVREIEGVAGIHLMAIEWEEVVPEIVGAAG
LLPRPSPLT
>A0A2H9M699|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeum sp. CG03_land_8_20_14_0_80_32_618|TrEMBL
MYKITDIFKRKKKTFSFEFFPPKTEEGMKHLFETCDELKKYPDFFSVTYNPDGSSRERTL
FVVNEIQKKFKIPVMHHLTCINYNERTL
>A0A7W8K3W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. K2C7|TrEMBL
MGVAVERKPFPLPASDITDAYSLEVSAKDIAALSAAAPRILPASTISVPYLPREDNDARL
AAVLAIRRLGFEPMPHFSARRIASLAEFESFVRRAAAEAGVERCFVIAGDPSTPMGPFSD
SASLIDTGVFERSGIKLIGVGGHPEGHPVMNKAEQWDVLERKCHSIGQRGMAPLIVTQFA
FDAEIVLAWLKALRERGIDHPVRVGVPGPANIAVLARYAALCGVSACASMWSKYGVSIGK
LFGTAGPDLFVDRLASGLTEAHGKVSLHFFPFGGIAQSVKWIEQYRSRA
>A0A847JS01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthonomonadales bacterium|TrEMBL
MLSYEELKSRLTDRIIVADGAMGTLLSERHVPLPYERANLTDPDAVFSAHREYVAAGAGM
IETNTFGANRIKLGSYALDRSIREINCEAVRLARRAAGSDTLVAGAIGPCGRALAPSGAI
HAREAWQAFAEQAAILLEEGADLILLETFHDLEELRTAHDAVRSLGDVPVIVQKVFVEDG
ATLSGGLPERFAVEVGAWSGVVAIGANCAIGPQRMVQIIRAMAAHTPVALSAMPTPGLPQ
RVGNEIRYAVTPEYFGKQAHLLVDAGASIVGGCCGTTPEHVAAIARALKDRQPADRGRAT
RTPVILPVAEAPLPASTSDYSELSRRLGKRYVTAVELDLPRGHDISKVIEGARALRESGV
DVIDISDGARARLRMNAIAVAHLVQEHAKIEVMLHFACRDRNLLAVQADLLGAHALGLRN
VLAVTGDPALIGDYPSATSVYDVDSVGLVRILRRFNEGIDLAGASIGQATAFTIAVAFDP
LARDPAKELDRLERKAAEGAHVVYTQPIFDEQALETAARAAEHVRLPLLFGLLPLRSARH
CEFMHNEVPGIRIPDEIRARMSELEEADARRYGLDVARGFLTLARNCTQGVYVMPPFGNH
KTAQAVLKALE
>A0A4V2WJ17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. 12DCB1|TrEMBL
MFICELFQQKKVVSFEIFPPKLTSSIEVIYDTIDALAPLRPDFISVTYGAGGSTSKTTAE
IASIVENKYNINSLAHLTCITSSKEQIEETLTQLADSNVSNILALRGDIPKGAGEIGRAR
DFQYASDLVAYIQNKHSFCLGGACYPEGHPECPDKDQDIENLQRKVDAGVGFLITQLFYD
NDAFFRFQEKVAKLNINVPILAGIMPITNRVQIERILALSNARMPQKLIKILDKFEHNME
ALKDAGIAYATKQIVELLANDIDGVHIYTMNKPQIAKDLVRNLDSLFYAVNSQENKKVGN
LD
>A0A7V8CRV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. FT58W|TrEMBL
MATHNFSIEFFPPKTPEGAEKLRVTRAKLSELQPKYFSVTFGAGGTTQQGTLDTVREILA
AGEEAAPHLSCVGGSRESIRAVLGEFKAAGVNRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLQAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKLGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTSLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVR
>A0A8H9Y642|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium bovis DSM 20582 = CIP 54.80|TrEMBL
MCQESPGATTHRRSHQIAVSDTLTFTTPGRVPFSVEFMPPRDDAAETRLWNAAEAFHDLG
ASFVSVTYGAGGSSRRRTLRVARQLARKPLTTLVHLTLVDHTRDELRAILRDFADQGLTN
LLALRGDPPGDPLGDWVPTDGGLNYASELIDLVRSEPGCEDFDIGVASFPEGHHRARDLE
EDTRHTLAKLRAGARYSITQMFFDVDHYLRLRDRLAAADPEHGAKPVIPGLMPITSLRSV
RRQMELAGAALPAELERRLLRAAAGDEEANRPAVREVGIELTTTMAERLIAEGVPDLHFM
TMNHPRATQEVLHNLGMAPAWGPQWGQDAVR
>A0A1H2Z011|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. PDC88|TrEMBL
MADLREVLKNEVIIGDGAMGTQLYQMGVPVGVSYEELNLTSPEMVKDVHRRYIEAGARLI
ETNTFSANYVNLSKYGLEDQVEAINRAGVRVAREAMGNKGFVVGAVGAIRAGKRADISAA
KLNLYFEQQISALVGEGIDGVLLETFYDVEELVIAVRQVKKLTDLPIICQFAIDDVGRTF
DGFTMPEAFSILHKEGADVIGFNCRTGPNGIMRAMESVQNLGIPMSVFPNAGLAEYVDGE
YRYGASAEYFGQSAVRFADLNARIIGGCCGTTPEHIKAMVSALDTYEAAPLTVVDDELLP
LPDSVSETLADGSAAGTIRTEPTIVDLVKERHTVIVELDPPRDLDIQKFLTGAKSLKKAG
VDALTLADNSLAVTRMSNMALGYLAKEQTGLRPLIHIACRDRNMIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPDSSSVYDLTSFEIIRMIKQLNSGIAFSGKPLKQKADFIVGAAFN
PNVKYLEKAVQRLEKKIAAGADYIMTQPIYDPKLFVQLKEATSHLDIPIFVGIMPLASGR
NAEYLHNEVPGIQLSDAVRERMAGLEGEEGRKVGTAIAKELLDVAMEHFNGIYIMTPFMF
YGMSEELTHYVWEKSGRVIKT
>A0A432GID0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR324 cluster bacterium|TrEMBL
YASELITAIREHSDFGIGAAGYPEGHLENPDKDDDRKHLHEKIAAGAEFIVTQFFLENTH
FLRWRDQLRREGASVPLVAGILPPANWKATKHMSEMCGVSIPEDLAQALIKNETDPEASR
EIGFDHVENQFEELLQEGVEGVHLYALNRLSTVERLGPILKDASGTISTPHL
>A0A349TEL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp|TrEMBL
MDSPLFYGLAGDIDVSFEFFPPKTEKMADTLWQSVETLGPLAPRFVSVTYGAGGSTRERT
HQSVVRIQNEANIPAAAHLTCVETTREQVDAVARHYWEEGIRHIVALRGDPPDGQSSYTP
HPGGYHNAVDLIAGLKKVADFEISVAAYPEVHPDSSDAQADLDNLKRKFDTGATRAITQF
FFEPECFFRFRDKAAAAGIEGEIVPGVMPVLSFAAVQRMSGLCGTAIPDWMEGLFAGLDE
RPAARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHMLGKRPAGTLK
>A0A432GDN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR324 cluster bacterium|TrEMBL
MHLIELYKKKDFVFSIEIFPPKTAKGMEKLKTTLEAFKSCTPDYFSVTYGAGGTSRENTH
ELAAHIHHDLDVPAMAHLTCVAHTVEEIDVVLSNLKNSEITNVMALRGDPTAGTKHFVQP
KGGYHYASELITAIREHSDFGIGAAGYPEGHVENPDKDDDRKHLHEKIAAGAEFIVTQFF
LENTHFLRWRDQLRREGASVPLVAGILPPANWKATKHMSEMCGVSIPEDLAQALIKNETD
PEASREIGFDHVENQFEELLQEGVEGVHLYALNRLSTVERLGPILKDASGTISTPHL
>A0A3B7R143|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter oligotrophus|TrEMBL
MKVTDHLAQANGKTLFSFEVLPPRKGENIQTLFSNIEPLLEFKPPFIDVTYHREEYVYRQ
RAAGLLEKITTRKRPGTVGICAAIKNRFDVDTVPHLICGGFSREETENALIDLHFLGIDN
VLALRGDPIKSEPGFVAHPNGHAYACELIGQVSAMNGGRYLDEEQVDSAATSFCIGTAGY
PEKHFEAPNLNTDMRYLKQKIDCGADYIVTQMFFDNQKFFGFVDKCRQAGITAPIIPGLK
PLTSKKQLTMLPRTFYLNLPEELVEAVAQCRDDADAREVGIEWCIQQSRELMAAGVPCLH
YYSMGKSEAVRRVAAELF
>H0C4L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. NO-1|TrEMBL
MTVASNQRTGFPVSFEFFPPKTPEGADKLRAARQQLYALRPDFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREQLATLKGMGVKRLVALRGDLPSGYGAGGEFHY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADIKAYIAKVQAGADSAITQYFYNSD
AYFRFLEDTQRLGASVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGV
>A0A2R7M940|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. HMWF029|TrEMBL
MNAANAQGIGFPVSFEFFPPKTPEGADKLRVARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFHY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLEAYVAKVQAGADSAITQYFYNSD
AYFRFIEDTQRLGAEVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A836GVV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania sp. Namibia|TrEMBL
MSGLILDAIAAEDVGKWYTSYEFYPPRSEKAEEEFMKVLISKFIRQSPVFLDLTWGAGGR
TSETTMRLCKDLQHAYPDTPINMHITCTNMPRGLIKETLDFAKAHGIRNILALRGDPPHG
EEYQANPDGFACAKDFVRYIHATYGDYFCISVAGYPEGHPSRIAEDGTISDEDSQKELDY
LKEKVDAGASVVITQLFYDASLYVKFVKRCRERGIMVPILAGLLPITTYAGFKRMVSLCK
TSVPSDVRKRVEELKDNPEGLKEYGVEQCVQMIEHIRSSGLDYHHLHFYTLNSSAQTFKI
LKRLDALVE
>A0A841Z101|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria newyorkensis|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARIAAPSL
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIVANVSMHEPGLL
QSGQTLASALQELADLGADVVGANCRLGPYHMSKALESVPLLENAYLAAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRRGLKSIKPVTSKVVHPIL
ELAELDAAEDAGVRLTDKVKEQYTVLVELDPPRTFDTAEFFEGAQKLDAAGVDAITISDN
SLATPRISNMALAAILKQEYDIRPLIHLTTRDHNLIGMHSHIMGFHKLGIQDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALVEAGITVPVFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREADKSGTGREEGMAIAKEILDAICEHFNGVYIITPFLRYDLSIE
LTKYVQSKETIAEVSSQN
>A0A7D7A1F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia huaxiensis|TrEMBL
MSFDNVRGYSTPGRVSRTPQVSGTRSIVQQLGPRPDGSVPFSIEFNPPRDAAGEARLWRA
AREFERLHPAFVSMTYGAGGSTRDRTIRVTGQLARETTLLTVAHLTAVDHSVAELRSIVG
AYADSGIRNLLVLRGDPPGDPLGDWVKHPEGVEYAEELVRMVRDLGDFHVGVASFPQGHP
RSADLDTDTRHLVAKLRAGAEYSITQMFFDPEHYLRLRDRALAADPVEGAKPIIPELMPI
TSLRTVQRAVELSGRELPTALLDRLHKAAGDGPEENRAAVRAAGIEIATEIAQRLIDEGA
PCLHFITLNFAKATSEVLANLGYTMSPAPAHA
>A0A438D042|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vitis vinifera|TrEMBL
MDRMVAHGPAFCDITWGAGGSTADLTLEISNKMQNMICVETMMHLTCTNMPVEKNRPCSR
HHQVQWHPECARPPRRPPSWPGQVRPDPRRLRLCSRSECVCLFTQVQHIRAKYGDYFGIT
VAGYPEAHPDVILNGVATSEAYQSDLAYLKRKVLCFYLLNVSCLCPTLIRRTRVFNCLIL
ECLYFLGRENIGIVV
>A0A088QJ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. ATCC 6931|TrEMBL
MSSTMPLSPGRQVTIRQALSMPSAGSIPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFA
SVTYGAGGSSRDRTLRIAQRVSKQPLTTLVHLTLVEHTVDELREILRSYLSAGLTNLLVL
RGDPPGDPLGPWVETEGGLHYASELIELIKAEPEFEKFEIGIASFPEGHYRSPDLDHDTQ
YTLAKLRAGAEYSITQMFFDIEHYLRLRDRLVEADPVHGAKPIIPGLMPITSLRSVRRQV
ELSGAQLPSDLEERLIKAADGDEQANKDEIRKIGIEFSTNMAERLIAEGVPGLHFMTMNF
ARASQEVLHNLGMAPAWGTGQDMLRGGF
>A0A1M3NKI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 65-9|TrEMBL
MALNFLRGAGRAPVATPRVSFEFFPPKNAEMEASLWSAIRRLEALNPAFVSVTYGAGGTT
RERTHNTVKRIVEETTLKPAAHLTCVGATREEVDEVVQGYWDAGVRHIVALRGDPAGGLG
SAYVPHPGGYQSTPDLIAGIRKIGDFEVSVSAYPEKHPESASLEADVDLLKRKVDAGATR
AITQFFFYNDLYWRFLDRALAAGINVPIAPGIVPVQNFKQTASFAAKTGAYISAELSRRF
EGLDNDPETRRLVAAAVCAEQVNELISRGVSDLHFYTMNKADLVYAICHLIGMRPAPEES
AARVAAE
>D8JFN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter oleivorans (strain JCM 16667 / KCTC 23045 / DR1)|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLRIVHQELQLLNPDFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>X0I7X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. conglutinans race 2 54008|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDDVKGDDERVKMVGVDIVSELIDKIKTIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A1E9M279|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC069D01|TrEMBL
MATVHPALSFELFPPRSQASCESLLRTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSDAE
LHRIGVKYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEY
A
>A0A0V1CXY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella britovi|TrEMBL
MPALLMPSVPKGMSNIFVFTYGLLYNMNSTYNLQVKLKSPAYQRAVTVAKVGNPSQQTDF
GVYFEEDSFLSLMASLEAVELKATRHDLNSAAKKSTDEIYRPLIDRIKENISSGRRFFSL
EFFPPHTTEGLINLLKRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCILNFCLL
DTMLHITSVQYDEKTVLFNLERAKKIGIRNILALRGDISDDANVTTTDFQYACQLVRFIR
SHYGDYFTICVAGLYLLYAKVDAGADFIITQLFFNEMHYFKFVSDCRKIGIVVPIIPGIL
PIQSYQSIMKIVQLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRKLLNREHHVV
PGLHFYTLNQEKSILEQIGFWKKVPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYLCR
TRDWKQFPHSRWGDVGNPAFGDLKHYLFSSIDQMDDSCALDMWDKELSTLEHVRDIFCNF
IARTPNRHGHSVRRLPWNENHLDPAADVLKNELIYYNSNGILTINCQAAVNGLPSSDPIF
GWGEANGYIYQKGYLEFFASSTCTTILLNHVQNFPSINYHAINFDGSFETFNYDEDATVA
LTWGVFVGQEIVQPTVANAASFRVWKDEAFDLWQRWAGLYESGSIGRKLLQRIHDDYRLI
TLIDNDYPQPCSLSALLRAVISDYIGGKNLTTDDDRLAYFDWQCVRECVRACAYVENSGR
LALRASKHGITAEKEEEEEEAIIE
>A0A175CV05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc inhae|TrEMBL
MTKISKIYYTKSAPVLSFEIFPPKKETGIELLYRTLDEVNPQKLGVDYISVTYGAGGLGD
NTKTCNLAQYIQTHLGVTALHHLTGVNQTPESLRDILAKVEQANIENILALRGDLGDKTY
VNVNYPYAKDLIYGIKQLRDFNVGAAIYPEGYTGNPITGISIAGTKEKIASGADFLISQF
FFDNDMYYNMQERLKNNYIKVPVSAGVMPIISKTQIERVTHMIGSPLPTELVNIVHKYED
NSEDLKKAGIEYALKQIQELLDHGVDGIHLYAMNQPSVLKSMLPIISQEIKTKHFFENNI
SDHG
>A0A6B0SFA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacterium bonnevillei|TrEMBL
MPFDSFGDQLDHLPDGATITITASPTLDLDATIDWAERAAERGYEVVPHIAARYVEDEQH
LASISERLRGVGVTDIFVPGGDLEEPVGKFDSAYQLLRALDELEYDFQDVGITGYPEGHG
FLSDETLAESMAKKAPHATYISTQLCYDPDAIVEWTETIRNRGIELPIEVGIPGVMKYQK
LIGISQKVGVGDSVRFLKKTSGILGFIKQFVGSRGKYEPDDLVDGLAPYVNDPEYGFAGL
HIYTFNQVPDTESWRRQRLRSV
>A0A7X5Y3C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas kaistensis|TrEMBL
MATGIDPRALLDHWSIEITAKDTDDLVRAAPLIPPGTKIPVTFLPNETFEARVSAAATVR
RLGFIPIPHLSARRIHSREELEGFLSALQREAAIDHAFVVAGDPPEPMGPFADALALIQS
DLLAAHGVTRVGISGYPEGHPEIGSDKLWDAGRDKRLALQERGHDFAIVTQFAFDAGPVL
KWIAHQRAEGIQALIRVGVPGPASVKTLLRFAARCGVGASAKVMSRYGLSMTRLLGNAGP
DRLIEDLAAGLDPAIHGDVRLHFYPFGGIENTAAWIRNYRKKLA
>A0A6B1D862|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineaceae bacterium SB0661_bin_32|TrEMBL
MVNSDQTPSPGDWELQSGESRLLQVLEAGHFAVTAELNAPDSADPKDVYANVAELGDVCD
GINATDGSGANCHMSSVACCALMARAGYEPVLQMGCRDRNRIAIQGDLLGAAALGVRNVL
CLTGDDVSAGDQPEARRVFDFDALHLLRTARIMRDQGVLLSGRKLTTPPDFFLGAAANPF
VPPQDLRHLRLAKKIEAGAQFIQTQYCYDLPVFESFMRRARDMGLHEKVYLLVGVGPLRS
ERAAEFMRSRVPGVHIPDAVVDRLAKTPRKRKRAEGIRICVEIIEEVKQIEGVHGVHIMA
YRQEEAVPEIVERAGILREKPKK
>A0A426VVK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MFEKFCDILCNDKKFITVEINPPHGASIDGILEDIKKNNLQEKVTGFSCTDNPLAKLKMS
GVLSAIKVQQTFNKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKYSDQPE
VKGVLERDSTLLLSIIYHLNNGVDYSNKPLDPAPKPIYPFAVSNAYARNMKSLQKRMIKK
LDYGARAIITQPVYDLENAKELLELFEEAKTMSVRDTAKEAHLILGQFPIVRAKTANFID
DKVPGISVPKPIIDEMNLAAMDGEDKEQEVGYALSKRIFDDMMKIHGKVHLMTHNRFDLC
SELIG
>A0A5J5D993|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Etheostoma spectabile|TrEMBL
MFACAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTFLKFLDDCRAIGITC
PILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKENDAAIRNYGIQQAVEMCRVLL
DSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRSVAPVAPLALQHGGGLFPGQGNSSSP
AFGELNDYYLFYLKSKSSKDALLKMWGEELLSEESVYEVFTCYIAAQPNRSGHKVMCLPW
NDEPLAPETNLLKDELEKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAP
DMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYI
HDNYFLVNLVDNDFPLESCLWRVINDMFELLDATPEPLDATPEPLDATPELHNDATPEPL
DATPEPLDATPELHNDATPEPLDATPEPLDATPEPLDATPEPLDATPEPLADATAAQ
>A0A2N7YD00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GP01-A4|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYHPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNAESYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>W7T9Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kutzneria sp. 744|TrEMBL
MTSVVERLGGPDPVFSVEFFPPRDAADEQRLWLAIRQLEGLEPAFMSVTYGAGGSSRDRT
IRTTGRVVQETSLLPMAHLTAIDHSVAELRNVIGWYAAVGVRNILAVRGDPPGDPNGEWT
RHPQGLTYAEELVTLVKQLGDFCVGVAAFPYGHPRSTDLDADTENLVRKFRAGAGFAIAQ
LFFEAEDFLRLRDRLAARGCDAPLLPGILPLTTVRTLNKTVELSGAPVPPSVAKRLDPYA
DDPKAFRAAGIEVVTDLAQRLIDEGVPGVHFYTFNRSKATTEVVERLGLLPARA
>A0A640P3L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. KUL106|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
QGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVFLRFRDRAAAAGVDLDLVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGA
>A0A3A8PJC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus llansteffanensis|TrEMBL
MKIRNCLNPSQPCFSFEFFPPKTDAGVASLLRTVEELAPLNPGFVSVTYGAGGSTRDRTV
ELVTHIKQHTGIEAMAHLTCVGHTRDELRDVLRRLAAARIENVLVLRGDPPQGQQTFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVSALRARS
>F5XRU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microlunatus phosphovorus (strain ATCC 700054 / DSM 10555 / JCM 9379 / NBRC 101784 / NCIMB 13414 / VKM Ac-1990 / NM-1)|TrEMBL
MVGRNVYATRPPTVAELLHAAERPLFSFELFPPKDDEQGRLLWDTVRRLEALGPDFVSVT
YGASGSTRDRTIELTHAIAEHTTLRTMAHLTCASQSRDRLRQVVGAYAGVGIRHILTIRG
DMPGGPLQPWVRHRDGLANATELVELVHSLGDFCIGVAAFPDLHPEQHNADLDARILVAK
EQAGAGFAITQLFFTAEHYFELVERVRALGSDLPIIPGIMPVTRLSQIQRFAELSGAQLP
SWVVDRVTAAGNDPAAVRQIGVEMAIELSQRLLAGGAPGLHFITMNRSTATLEILREVEP
LARVH
>A0A4Q5VQ76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxellaceae bacterium|TrEMBL
MAIPVSFEFFPPKTDVGAEKLIVVHQELQQLNPQYFSVTYGAGGSTRERTLSTIDALHGQ
GAPVAPHLSCIGDDKARIAELLDIYKAKGINRLVALRGDLPSGQVGLGELPYATDLVRFI
RDHSDDYFHIEVAAYPEMHPQASSFDQDIERFADKVRAGANAAITQFFFNADSYFYFVDR
IRQLGIETPIIPGIMPITNASNLIRFADSTGAEIPRWIRKQLATYGDDSASIRAFGHDVV
VKLCQRLIDGGAPALHFYTMNQTEPNRQLVKDLGLA
>A0A2L0WM46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. NXC24|TrEMBL
MQNVEIAEASVGEPEALPHATLFDSFSIEITGKDTAALQGASHLLAPATSVSIASIPGES
HDARVAAAVTARRLGFQPVPHISARRILSTAELDALLARFIREADVHSLFVVAGDPDVPM
GPYGDSLALIRSGLLSKYGIRKIGIAGYPEGHPKINSPMLFDVLREKHDLLTAAGLEYDI
TTQFSFDAEPVIGWIERIRKLGITAPIRIGVPGPASVKTLLRFATICGVGASAKVMTKYG
LSIGKLLNTAGPDVFVSELIRRLAPAALGTVRLHFYPFGGVGKTAEWIRDFPSNQR
>A0A513TZM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseus|TrEMBL
MTTYSFEFFPPKTGKGAAALWRTVRRVEALRPDFVSVTYGAGGSSRDHTVEVTHRIATET
TLRPVAHLTAVGHSVAELRRIIGQYADAGIRDVLVLRGDPPGDPMGPWVSHPDGFTHAYQ
LVELVRSLGDFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFRVEDYLRL
RDQVASAGCDTPIIPEIMPATDVRQIRRFAELSGATFPQDLARRLEAARENAADGYRIGV
EHATAMADRLLAEEAPGLHYITLNRCAAALEVHHNVVASHSASVRSVRT
>A0A0Q8AJ51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. Root157|TrEMBL
MSQFRFSRRPDIGDKIRVSFEFFPPKTDEMEKRLWETVTRLEPLRPQFVSVTYGAGGSTR
ERTARTVARILGETGLHPAAHLTCIDAGREEVDEVIKQFVDLGITRFVALRGDPAAGVGT
RYQPHPEGYANGADMVSALRRHGDFDISVSAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDVYERYVERVRRAGIYIPIVPGILPVHNISQVANFSERAGAHVPAWLRERFE
GLESDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLAFAVCHMIGIRSHRPAIG
SANSAAA
>J9SLR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp. KTR9|TrEMBL
MRPAPYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFFPPRDAEAESRLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSVAELRALVGAYADQGIT
NILALRGDPPGDPLGEWVAHPDGVEYAEQLVRLIDTLGDFHVGVASFPETHHRSPDIDHD
TRTLVDKLRAGAEYSITQMFFDVEHYLRLRDRVAAADPEQGSKPIIPGIMPVTSLATVRR
MVELSGSVIPPDVEERFAKAAGNGAEEDRASVRAVGIDFATEMAQRLIAEGAPCLHFCSL
NFAKATTEVLGRLGVDVDAALHVSA
>A0A1Q5G8V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02130|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVKA
TQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPESLKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>R0FNP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsella rubella|TrEMBL
MKVVDKIKSVTEQGKTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGSTA
DLTLEIASRMQNVICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRTKYGDYFGITVAGYPEAHPDVIEANGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITTLHLYTLNVDKSAIGILMNL
GLIDESKISRSLPWRRPANVFRISEDVRPIFWANRPKSYISRTKGWNDFPHGRWGDSRSA
SYSTLSDYQFMRPKARDKKLQQEWVVPLKSIDDVQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLGKVNSNGFLTINSQPSVNAAKSEFPAIGWGGPGGYVYQKAYLEFFCSKEKLD
TLVEKSKAFPSITFMAVNKAENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEEDPSRKLLEEVKNSYYLVSLVDNDYINGDIFSVFA
>A0A430VUR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus|TrEMBL
MKIRDLLKAQEGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRDRS
VLWAKRILDLGLNALAHLTVAGQSQEEVAGVLDRFVEAGVENILALRGDPPQGERVFRPH
PEGFRYAMELVAFIRSRYGEGVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRMGIEIPILPGIMPITSYAQLRRFTEVCGASIPGPLLSRLERYQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNRSPATRRVLERLGFKPT
>A0A231NPK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacterium sp. MES1|TrEMBL
MRITELFERGEFVLTAEVGPPKGVELDHLIKDAHEYLKTRVHALNVTDNQSSVMRTGSLA
TCRVLKDEGLLPIFQVTCRDRNRIALQSDILSAALLGIENLLLLTGDYTTLGDHPQAKPV
FDLDSVSLIHAVKRLEEGFDIAGNAVDGAPPKFAKGAVVSPCSDSVDVQLAKMEAKVKAG
CEYFQTQGVYEPEKFIKFMEQAKQFGVPVQLGLIIPKNVGMCRYMNANVAGVHVPDEMIA
ELQADKEKTKAGDTGVEICARLIRECKDYAQGVHIMSLGWENRIPEILDLAGIAPITPVV
>A0A7Y0U1Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobiluncus mulieris|TrEMBL
MASGVDWVAPDAGGVLDAPGAPVAFTSVSRGANPKSSRNPTRPVRVSFELYPPRNPDPFS
QAWAGIDRLLDAHPDYVSVTFGTSNSTSASSQSVLAHALQRLGRPVLAHLTCVGKTRAEL
STTITEMLDIGVRDFLALRGDNPKGSVNWEPAPGEFSRASQLVTLLREVAAEYLGDARAI
SIAVAAYPAGTVSARTNAVAALAEKQSAGADFAITQVFYNADDYGALLDSATYQGVSIPI
IPGIIPFTDAARLQRLEGLTGVSVPSRLQAISEISDPEERFLEGLSATLDFVNDLIQAGA
PGLHFYTFNRPRPVLDLVEHLRSRGFTHVDEDSSSELLDLVNAAMQRFSP
>A0A843BF36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas suwonensis|TrEMBL
MSYPVSFEFFPTKTPEGAAKHVAVRQALYARKPQFCSVTYGAGGSTQAGTFTMVQDIQSE
GVSAASHFSCIGATQDSVREELTQLKAMGVKRIVALRGDLPSGYGLGGEFHYASDLVAFV
RQEFGDWFYIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VKALGLDVPVVPGIMPITSSTQLMRFSDACGTEIPRWIRLRLQAYGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A3M7N5B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetothyriales sp. CBS 135597|TrEMBL
MHISSKLNAAHSQGRPTFSFEFFPPKTAQGVQNLYERMDRMHDLGPAFIDITWGAGGRHS
TLTCEMVSAAQTNYGLETCMHLTCTDMGRAKIDEALRRAYKSGCTNILALRGDPPREQEK
WQSKEGGFRYAKDLVQYIRSTYGDHFDIGVAGYPEGCDDQPDTDLLIDHLKEKVDAGATF
VVSQMFYDVDIFLAWVKKCRDRGITVPIIPGIMPISTHQAFLRRANWTKCHVPEKWHTAL
EPVKNDDSAVKEIGRDLVVEMCRKILDAGILHLHFYTMNLAQATRMILEELNLTPETSGV
PLNKPLPWRPSLGFGRREETVRPIFWRNRIASYIARTTEWDEFPNGRWGDSRSPAFGELD
AYGVGLKGSNESNIKLWGKPSRLREIADLFTSFVEGRLDRLPWSEGSISAEADSIKSDLI
EINRRGFLSINSQPAVDGAPSSHPVYGWGPQGGFVYQKAYLELFVFPSVIDEVMKRLEAN
KNLTYFAVNKNGTLRTNSPDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WSRCYPQGSASRRLIETMMNQCYLVNIVNNDFHQTHEIFRIFDDLEVADIDQVFEDDADQ
LDQNGIQATANGTTT
>A0A0Z8EWV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELQIPTIAHLPAAYLTKEKVQSILHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARTIHQATHSLFKHYS
>T1D3Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter fennelliae MRY12-0050|TrEMBL
MLDSLITHIHSNKPFLSLEVTPNLGANLSSSLISELKDCTKAHAFVCTDSPLARLKPSSL
LSSLKLQNALGKPVICTLSMRDRNSIALSAEILAINELGVRAFLSLTGDPIKLGDCADSK
GVFESNSLKLAQIISQLNAGYALSGKPLDSAVQRIYNFSTISSYAQNPKTLESKIQKKIT
SGCEALFSQPVYSPESAEMLLQNIQRANASTGKSAQGKSAQLILGFFPVMSYKAALFLRD
KLPGVFIPDDWVERLQKASQIGKDEEHKVGLDLSLQLFKALQKIHNKIHFMSSNNFALFK
QFADI
>A0A660S562|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteria bacterium|TrEMBL
MKIKTNLQKVLESGQFAVTAEIDPPKNADPELIKEKAKWLKGYVDAVNITDSPRATVKMS
SLAGAVILQKENIEPVMHITCRDRNRIAIQSDLLGASALGVKNILCLTGDYVTFGDHPQA
KPVFDLDSIQLISLVKNLSEGRYFNKKEVKGKHPYFFIGAVENPFADPLEFRPIRLAKKI
KAGARFIQTQIVYNLERFEKFIKLCEDFGILEKVYILAGIAPPKSLKMLKYIKESKIPGI
EVPDELIRRMESAKDEKEEGINIAVEIIERVKENPGVRGIHLMPIGWEFIVPEIVKRAKL
YPRPKIC
>A0A416L0R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF27-5AA|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPELCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A515BDL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter tandoii|TrEMBL
MSKKVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDLDIQRFCDKANAGANAGLTQFFFNPDAYFYFV
DRIQKEGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A380M794|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus viridans|TrEMBL
MSIQSPSLSFEVFPPNPAVGNEKIMAALKEMQDLVPHFISVTASNNKFNIEETTVRLADF
IRNDLHIPTIAHLPAVYLTKEMVTETLTALDKVGVHKVLALRGDILPDVEPQKDFVYATD
LIEYIKKEAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYD
FQDKCILAGIEVPIHAGIMPILNRNQVLRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSDTAHRIYQATHTFFNK
>A0A370TTI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Venustampulla echinocandica|TrEMBL
MHISAMFPEAGQPRQPQFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFVDITWGAGGRLA
SLTCEMVNVAQSQYGLETCMHLTCTDMGEDKVDEALKNAYKAGCTNILALRGDPPREEEK
WVATEGGFQYAKDLVKHIRDVYGDHFDIGVAGYPEGCDDQDDPELLLEHLKEKVDAGATF
IITQMFYDVDNFLAWVLKVRAKGITVPILPGIMPINTYASFVRRCNHMNATIPPKWSQAL
EEVKNDDAAVRNIGTGLVAEMCRKILDSGLIHHLHFYTMNLAQATRMVLDELDLAPSEER
PLKPALPWRKSLALGRRDEDVRPIFWKHRNKSYVARTQDWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEQNRKRWGEPASIEDIADIFVKYLENGVDSLPWSEASITSEADVIKDDLI
ALNRRGLLTINSQPAIDGVKSSHPVYGWGPKNGYVYQKAYLELLISPKLIDELLRRIEQD
PDLTYYAVNKAGVLKTNTPGEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEAFRLGLD
WAHCYSALSPSRQLIGNMMETWYLVNIVHNDFHHTHGIFPLFDGLSVEDLEKPFEVAGTN
GVEPSGVNNAVPNGVGDTPLTNGNTGNA
>A0A385BPZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariniflexile sp. TRM1-10|TrEMBL
MKVTDHIKKANGKTLFSFEVVPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVD
KGNGLLDKRITRLRPGTVGICASIMHKYKVDAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VVALRGDSRKDEPYFVPTKGGNAYASELVQQITNLNNGKYLHDEIEVEHNYDFCIGVAGY
PEKHMEAPSFNSDLKRLKEKVDAGADYVVTQMFFDNKKYFDFVERAREIGITVPIIPGIK
PLAIKRHLQILPQVFKIDLPEELIEAVEACKDNIAVRQVGIEFAIQQSKELKAAGVPFLH
YYSMGKSDNIKAIASELF
>A0A414JXZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gordonii|TrEMBL
MVRHHTPSLSFEVFPPNPAVGNEKIIQALREMQDIAPHYISVTASNNKFNIEETTVRLAD
FIYNDLKIPTIAHLPAVYLTKEMVSDTLQALDKVGVHRILALRGDIFPDVAPKDDFKYAT
DLIEYIKEAAPHFDIIGACYPEGHPDSPDRVSDIRNLKKKVDAGCSSLVTQLFFDNDRFY
DFQERCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRS
AGLAYAIDQIVDLVTQDVAGVHLYTMNNAATAHHIYQATHTFFS
>S5T484|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cycloclasticus zancles 78-ME|TrEMBL
MSLESYQKISFEFFPPKTEEGRVKLLNVSKELGQLDPAYFSVTFGAGGSTQQGTIDTVLD
IKKQGFSAAPHLSCVGSTKASIRKILSNYKDNGVDRIVALRGDIPSGTLDIGEFRYANEL
VAFIREETGDHFHIEVAAYPEVHPQAANAQTDLANFKQKVEAGADSAITQYFFNFEAYVR
FVEDCDKMAINVPIVPGIMPITNYSQLARFSDMCGAEIPRWIRKRLEGFADDRESIKAFG
TDVVSELSQTLLDYGCPGLHFYSMNQAEASLAICRNLGISAK
>A0A6G6GL13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium RR4-40|TrEMBL
MKVTEHIKNANEKTQFSFEILPPLKGQNITSIFEGIDPLMEFKPPFIDVTYHREEYVYKE
REDGLLQKKVVRKRPGTVGICAAIQNKYNVDAIPHILCGGFTKEDTENFLIDLGFLGIDN
VMALRGDAVKSETYFTPERDGHAYAGELVSQISALNNGLYLDDEILNTTPTNFGIGVAGY
PEKHLEAPSLDSDIHFLKKKIEKGATYIVTQMFFDNAKYFQFVEKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSVELPDSLIKEIIKCKDNRGVREVGIEWCIAQSKELLAKGAPILH
YYSMGKSDNIRTIASAVF
>A0A840YWH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stakelama sediminis|TrEMBL
MTLSVDQLEEARRALDAPLFADLAGDAEVSFEFFPPKTEKMAQTLWQSIQTLAPLGPRFV
SVTYGAGGSTRERTHATVARIQRETPLNAAAHLTCVEASKDEINQVAEEYWAAGVRHIVA
LRGDPPSEGAKFQARPDGYQNAADLVAGLKRLHPFEISVAAYPECHPDSADQAADLDNLK
RKLDAGANRAITQFFFSPEAFFNFRDAAAAAGIDAEIVPGILPVSNVAQTRKFAGMCGAQ
IPAWMDRLFDGLDDHPDARKLIAATVAAEMVRKLYAGGVRHFHFYTLNRAELSFAICHLL
GLRANGAKVEAAA
>C8W678|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofarcimen acetoxidans (strain ATCC 49208 / DSM 771 / KCTC 5769 / VKM B-1644 / 5575)|TrEMBL
MSKSKIERLFDQGEFVVSCEIGPPKSTDAEVIREYARMLKNHVDAANLTDCQTAIVRISS
IASAWHCLEEGLEPIIQMTCRDRNRIAMQSDLLGAYSMGIRNILCLSGDHQKFGNHPTAK
NVHDLDSMQLVNMVKRMKDEEEFCCGEKFKNHAPKDFFVGAVANPFADPFEWRVARLEKK
IAAGARFIQTQCIFDTDRFVKFMDMVKERGLHKKCKIMAGVTPIKALGAAKYMKNNVAGI
TVPDELITRLEAANKAGGKDAVREEGIQICIEQIKMFKEIEGVAGVHIMAIAWEELVPRL
VEESGLYPRPALKE
>A0A1F8SJK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_19FT_COMBO_48_23|TrEMBL
MSLREKLQNGKFAVTAEIGPAKGTDIHEFNENADLLKGRVDAVNCTDQQSAVMRLGSLVA
CHLLKQKGIEPVFQMTCRDRNRIALQSDLLSAYVMGVENVLCLTGDYVTLGDHPDAKPVF
DLDSVSLLYAARKLEQGKDLADKELKGTPKFFLGACVTPGADPVEPQLIKMERKVKAGAQ
FFQTQAIYEPKTFEAFMKEAKKFGVPVLAGIVVLRSAAMAKFMNKNVAGIHVPDALIDEM
DKAENKLQKGIEIAARLINETKGMCQGTHIMAIGLESKVPAILDAAKL
>A0A4Q7B8X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. WCHAc060025|TrEMBL
MTKRVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLDDFN
GKGTPVAPHLSCIGDSKQRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQRFCDKARAGANAALTQFFFNPDAYFYFV
DRIQKEGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A3E4UBA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi|TrEMBL
MKISELYQAKQNQGNPSKKTLSFEIFPPKKDSELKNIDKTLAVLCELNPDYISVTFGAGG
GANRNRTIELAKRIKQEYHVEPVVHLTCLHYDKAEIDEFARVLANAGLQNVLALRGDKNP
DMREKESFCHASDLIAYLKGKWDFCFLGACYPECHPESEDKVGEIRHLKAKVNAGAEVLL
SQLCFDNHAFFRFQEACRIADIQAPIIPGIMPVINAAQIKRMITMCGATFPVQFQKIIQK
YESNKEALFDAGMSYALSQIIDLLVSDVEGIHLYTMNNPLVARRICEGIRNIV
>Q9F3S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermus marinus|TrEMBL
MKVIEILEQATGPLISYEIIPPRRGGSLEEVLAVVEELMPFDPPFIDVTSHAAEVEYEPL
PDGTLKPRIKRKRPGTIGICAAIKSRFGVETVPHLLCRGFTREETEDALIELHYLGIQNV
MALRGDSPNYQKPIPPDRTVNEYAVDLVQQIANMNRGIYLEPLEDAVPTDFCIGVAGYPE
KHFEAPNLTWDIMNLKRKIEAGAHYVTTQMFFDNRHYFRFVERCREMGITVPIIPGLKIL
TSKRHLQLLPSRFHIEIPEELVAEVEAAKPEHVPEIGIAWARRQAEELLEAGVPCIHFYI
MLRADYVREVVAYLRKIA
>A0A413LGF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi|TrEMBL
MKTTDLFAKKPVLSFEVFPPKRTNPVETIYETLDSLRKLNPDFISVTYGAGGSENCKATT
EIASKIKNEYGIESVAHLPCIGLTKDDVISLLGGFKRAGIDNILALRGDIPEGGRPAGDF
EHASDLISFIKEKEEFKDFNVVAACYPEGHTESENILTDIRSLKTKVDAGADHLITQLFF
DNDCFYRFKERALLAGIHLPVEAGIMPVTNKKQIERMVSLCGVSLPSKFTAMMERYEHNP
EAMRDAGIAYAVDQIVDLIARGVDGIHLYTMNNPYVASKIHEAVYRLLAA
>A0A1V5N496|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium ADurb.Bin401|TrEMBL
MGIGTPEYMAEYAKRFYEKGARIIGGCCGTTPAHIKEMVKAVKPLHKADLSSAFIEVKQQ
PKQVAAKTPVALKDKSRIGAKLASGQKIYTVEISPPKGTDVSSLIDKVKLCEKHGIDAVN
IPDGPRASSRLSAMITAIKIRQSCRLETILHFCCRDRNIIAMQSDLLGIQAVDIANVLII
TGDPPKLGEYPDATAVFDMDSIALTNVVNSLNCGIDIAGNALPKQTSLVIGVGANPVASD
LDREILRYKKKVEAGAEFAITQPVFDEKSLFKFLELTKDHNIPIIAGIWPFTSFKNAEFM
ANEVPGVVVPADILQRMSKTKDQQQGKKIGVEIAIELMDKIKDVVAGFAISAPFGNVNMA
LAAAGKIGIEKI
>A0A0M2X9U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium minutissimum|TrEMBL
MSPRLSASAPLDQISEDTPKELKRTALSFEVIPPRHDADAAKIDRLLATLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTEKELEAWIDTLVDAGVRGLLALR
GDLPEGGMPEGHLPHADSLVRLIRRWESDRVARLAAGRLAVGVACYPNGHAESATPDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTKVLDQLAAATSPEEEKEIGMQITASLAKSVMNAGADGLHIYTHNNPDITTDLL
NRIGVIP
>Q10VR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichodesmium erythraeum (strain IMS101)|TrEMBL
MNRFRNAVKSGEFLITAEVAPPKGADPTHMIQMAETLKGRVHAVNITDGSRAVLRMSSLA
ASMILKNVGIEPICQVACRDRNRIALQADLMGASALGLHNILALTGDPVKVGDHEKARSV
FDMESIRLLQMIAKLNQGIDWNEKALPDGSTDLFVGAAVDPQSPSWSGLKRRFELKLLAG
SQFFQSQLISDFDKLEKFMNQIAVDSNKPILAGIFLLKSAKNAAFINKYVPGIDIPEHII
NRLANAEKPLQEGIKIAAEQVKISSKICHGVHLMAVKREDLIPQILDMAEISPISN
>A0A7Y2IA35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
GAKDQKQEGVNLCVEMINELQQIEGVRGVHIMAFRQEDRVAEIVERSGVLGDREPWRPRR
EWEELASSDEEAVQI
>A0A7Y1XU37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MSNENKINVSFEFFPPNTDKMNDTLWHSITRLAPLSPQFVSVTYGADGSTRERTHATVAR
ISDETSLTAAPHLTCVGASCAEIDDIAREYWDMGVRHLVALRGDPPKDSGTYVPHRDGYA
YAADLVEGLKKVGDFDISVAAYPEVHPEATNALADLDNLRRKLDAGATRAITQFFFNVDC
FLRFRDLCAAAGIESSIVPGILPITRFPQLTRFAKQCGASVPDWLEDRFAGLDDDAETRQ
MIAASVAIEQARRLQSEGIHEFHFYTLNRAELTYAICHALGVRPKQQAA
>A0A7C6R053|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MKSGSNLEKVLVSGQFACTGEIGPPTYASFEEIDKHAREMKGKVDAVNFTDNQTAVVRLS
SWGASLRLIYEHGMEPNLQVVCRDRNRLAIQSDLLAAYAHGVRNVLCLSGDHQSFGNHPG
CKSVYDVDSVQLINMLKRLRDDGCFECGAECKVNPKFFIGCAENPFGDPFEFRAIRLEKK
IEAGADFVQTQCILDMERFELFMEKVRELGLHKRAFICAGLMPVKSPRMARYMQTGVPGM
LVSEEFCQRLEKAEDPKAEAVNITVEYIKRCQQIEGVAGVHIMAVAWESIVPTVIEKAGL
LPRPTF
>A0A7C2K7H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldimicrobium sp|TrEMBL
MDRFQRDLKEKDFIFTFELVPGRSIRTQQFSAILKFIEEAPKYEYLSAFSITDNAGGHPA
LSPVALGRVIKSLGLSAIIHLTCKDKNRNQLESELLALDRENLHNLLVLTGDYPFYGYLG
RAKPVFDLDSVLLLQLITEMERGIEIPKGAPGGGNRLPPIPFFKGCAVSPFKLTIEELWW
QYLKLYRKLKAGARFIITQVGFSPFTLNQLKLILKDGLTKYFSERLNDKGLHKPEEDSQF
KKVPILPSILYLQESVVKALLKGRVPGILLGRRVWKRFKEVGFSEEMALEVCAKLTAIYK
RMGFKGVHLCGFPPNWDILKRFFELYQRVSQDIMNKEETYYELLTEFDDYIVYEDNGELI
EKNLANIDKPLPKKSFSFSYSMNNFFHNLFFSRKSPLYLTLLKFFTWVTKKRSLEKFFST
LEYAIKRPLFYCQECGDCTLWDFNYICPQSQCAKYILNGACGGSINSFCEVYPYKKVCLY
VRVLRQGDPRETIKRYLTKDPPYLPPRDWSLYRTSSWINFYLKRGHFKHEN
>A0A3G2PSD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio owensii|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDASRDELINIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A3D1URI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaeria bacterium|TrEMBL
MDSSGIQLEMNFDGAMGNRFKEKLDNGNFQVLVEVNAPPSETKLADAVTRFSEIEYLVSA
KQELNAALTFTDRYAYPEALDNIQFAAALCKTDRDRHLICVSGRDRTVSDLEKILGHAAN
EGFKNIIAVSGESIKGDSLKQVQSRLFTESVHTLRSIREKFNKNLFAGCAVNPYKYTPCT
CFPQHFKLFKKISLGASFMVTQFGWDMLKLQELRWSLFRRSLHIPSIARFLVLTPDKAEE
ICSGKLPGVHISPDFQAMLRRETMHSMAQFEAAQWRRIQIHAAGARFLGYSGIQIAGLER
PDQINIMLNRIREALNEFAGFEEWRTAYQEYYARLDMAPYPYRFYEFEELFSKAHPSEMP
RMANAEIPPLEDGEKFKLNLAHKLFANADRLPASERYLTKKLLVSCRGCPECRLPSTAFV
CPETCPKGMANGPCGASKANGECEHTSKECIYSKRMRIAAQNNDYISLEETYVKPVDKRR
R
>K2PYY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium albertimagni AOL15|TrEMBL
MAHIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMAKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDHVIARLEGAADQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGILKGRRPWKREHARADDIAAERMREIGADPVQDQQTLAGLAA
NTQTH
>A0A6I2LNJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter sp. MDW-2|TrEMBL
MNQFPLSRRSDIGNKIRVSFEFFPPKNDDMEARLWETVTRLEPLRPQFVSVTYGAGGSTR
ERTARTVKRILEESTLTPAAHMTCVDATREEVDQVIAEFAAMGVKRFVALRGDPKEGVGA
AYQPHPGGYANGAELVGALKAQGDFDISVSAYPEKHPESPDFVTDFDMLKRKVDNGATRA
VTQFFFDNDLYERYVERARKAGIYIPIVPGVLPIHSFTQVANFASRCGAHVPGWLAERFE
GLDKDPQTHALVASAVAVEQVLDLVERGVNDFHFYTMNRADLVVAVCHMIGIRPQPVVQG
SAAA
>A0A7Y2V619|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MAPWSSYSMNEIPENKPHVSFEFFPPNSEKTEATLWKSVERLKSLSPRFVSVTYGADGST
RERTHNAVARIVRETGLTAVPHLTCVGASRGEIDDIARAYWDMGIRHLVALRGDPPKDAE
RYEPHPDGYAYAYDLVAGLKNVADFDISVAAYPEVHPEAPNPLFDLDNLKRKLDAGATRA
ITQFFFDSNVFLRFRDLAATAGIDSPIVPGILPITRFPQLTRFAESCGATVPDWLRERFT
GLDEDAETRQMIAASVAIEQVRTLQAEGVEEFHFYTLNRYELTYAICHALGVRPATTETA
A
>A0A1B1Z5G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fictibacillus arsenicus|TrEMBL
MSLVTDLKHNKILIGDGAMGTLLYSYGSDFCYEELNLSQPEQIYNIHRAYLNAGADIIQT
NTYAANYSKLERYGLQDQVKEINKAAVQIARRAAKNEYVVGTIGGIRGIKPNSISLDEIK
RSFREQLYCLLMENVDGIQLETYYDLQELETVLEIARKETSLPMIAQVSLQEIGFLQDRT
PISEALLRLEEIGADVVGLNCRLGPYHMLKTLEEVPIPKKAFISAFPNASLPSYSDGKFQ
YESDAEYFKECAHLFREQGVSVLGGCCGTTPEHIRAFSNELKNLQPVKEKEVKQRQRDIV
IQSASKSMYVPLCEEVKKKQSIIVELDPPRKLDTSGFMEGAKALKEAGIDALTLADNSLA
SPRICNSALGSIVQSELNLRPLVHITCRDRNLIGLQSHLMGLHTQGIREILAVTGDPASV
GDFPGASSVYDVTSFELIKLIKQFNQGLSLSGKELGEKTSFSVGAAFNPNIRLIDKAVER
LEKKIEYGADYFISQPIFSEEKLIETYEATKHIDKPIYIGIMPLTSSQNAEFLHHEVPGI
KLSDSVREQMGKFKESPKQASVEGLNIAKSLLDTAMDLFNGIYLITPFMRYELTVELAKY
ARMNHPSLLARRSQNA
>A0A165NTJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exidia glandulosa HHB12029|TrEMBL
MKITQKIERAAKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
DLSSELVKTCQGVIGIETCMHLTCTNMPAEKVDIALRDAKVHGCRNILALRGDPPAGQSE
WTAVEGGFVHGIDLVRHIRQHYGDYFDIAVPGFPQQALLPPEEFQQELQWLKEKCDEGVD
FIFTQMFYDVDVFVTWVKALRAAGITIPIVPGIAPIQTWNGFVRATSLAKTIIPKSFMDA
LEPYKNDDEKVRAIGIKLVADMCRTILESDLGIRGLHFYTMNLEKGTKMLLQELSLVPRI
ETIKPLPWRQSLTPNRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGDLD
GYGVSIKQTKEDAVSLWGTPTKLEEVAQLFARFCTRDLAALPWSDLPPAAETTVIDQQLA
RMNQLGFFTINSQPAVNGASSTDPVHGWGPANGYVYQKAYLEFFVSPELGAKLLPAIERN
PMLTYYAINRRGDLRTNSKSEGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELGMQ
WANVYEADSPSNKLITDIMNTFLLVNVVHNDFKDPNAIFETFFKVGEEHGLNYPANVLNG
KH
>G7I1Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium casei UCMA 3821|TrEMBL
MVPRMSASAPLDYLELDHAGNPRAAGVGKAPGRTSLSFEVIPPRHDADSAKTENLLQVLG
SYNPDYIAVTSSKRSGWLEGTAKFIAQISSTTSMRPLAHLACTAGDRQQLISWINVLVDA
GVRGFLALRGDLEPGQDKLPEGYLQHADELVRLIRQLEGEQAARFAAGRLAVGVACYPNG
HAESANADEDFDVILSKQRSGADLAITQLFFDAEDYLKFAQRARLAGTRIPLIPGIMPIT
SLKRVQRMGELSGLEVPQRLIEKLSLARSPDEEYAIGMAHTVELARAVLAGGAGCLHIYT
HNNASITQELLSSIGITPDVKKQP
>A0A1L9VH15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus glaucus CBS 516.65|TrEMBL
MEKLTDKIAALPPNSSYFSLEFFPPKTQMGFANLQARLERMAQALRPLFITVTWGAGGST
AKRSLELAEVCQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNIHGEDDSNKDFMFAVDLVKYIRQQYGNYFCVGVAGYPEGHPADSFQDVQDPHQDLPYL
IEKTKAGADFIMTQLTYDLDAFNNYESLLRNHESGVFKTIPIIPGLMPVHSYKILTRVTK
LSHVKVPPCIAKKMEEVKHDDDAVKRVGMDVIIDIVEGIKKVASPGIRGFHFYTLNLEKT
VSFILERCNLIPEYDENAIEDEGALNVAASTLDVAPNGSRIGSKSRASSLNSQPRNRVIV
DRKQANLEDATRDSASHEASAVSAGMPAMPPNPSTTLQISEGLGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVPAPAARRLWGHPVSRSDLSTLFRRHVSGELHMVPWSEGGS
EEGGDGLNPETAVIRPELLKLIDGRGWWTLASQPAVNGVRSDDPVFGWGPQHEGFVFQKP
FVEFFCPDKDFQNSLKPVLEKHGHEKLAWFATNAKGDFESSLPAHPAGSDNDDIVEMNPD
NVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRVYPRGTPTERFLEDTKND
VWLVCVVAQEFGAGTEVGSSEEEKEVKWMWRVLAGEE
>G8LUA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetivibrio clariflavus (strain DSM 19732 / NBRC 101661 / EBR45)|TrEMBL
MLKDKILNKRPGIITYGLTPPKAGNPPEKIKEIAEKQIERIKNLEIDGLVIYDIQDEKDR
TDAERPFPFIETIDPLTYSNEYLMDLHIPKIIYRCVGKYTHNQFCDLLKGYKGQDTFSVF
VGAASRKQKVSLHLSEAYEICSAVNPDIILGGVAIPERHMKNWEEHMRIINKFQSGCKYF
ISQAVYNVEAAKDFLSDYYYYCKNNNMEMVPIIFTLTPCGSIKTLEFMKWLGISIPRWLE
NDLLNSEDILNKSVSLSKEIFTELLEFSLEKGIPIGCNIESVSIRKVEIEASISLAKDIK
SIISSRGVI
>X1ML70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MAKSLFEEKLNSGKFLVTTEIGPPKGVDTSEIVHHIELLKDKVDAINVTDHQSSVMRFPS
LGGCLLIKEHGGEPILQMTTRDRNRLALQADLLLAYSRGIRNVLCLTGDAIEVGDHKEAK
PVFDLDSVQLIRMVRTMESGKDLAGHDLKGAPEFCLGASVHPAADFIEPQLIKFDKKVAA
GAQFFQTQGIYDLDTLHRFMQYAHQFNVKILAGIIVLASARMARYMNDNVPGIMVPNAII
DELASVEKG
>X0YSD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MQVINVLKKADKPVFSLEITPPEKGKSIQGIFDTIDMFKEFKPHFINVTYHQQKVVYTEK
KGIIKKIPKRKNVGTVGICSAIKHKYGIETVPHLICGGFNKYDTEDALIDLNFLGMENLL
ILRGDPRPEEKEFIPEKEGYKYASQLVKQVSDMNQGKYLEELNNGHPTHFCIGVAGYPEK
HWEAPNMEQDLLNLKNKVDQGADYVITQMCFKVNKFKEFVKKARDIGITVPIIPGIKPFT
IRLSPERKPAKFPE
>X0WTM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
KNEAYFKATEGGHQYAVGLVKQIHDLNQGKYLHEIIDTPYNSNFGIGVAAYPEKHLEAPS
MDSDLRRLKEKVDAGADYIVTQMFFDNQKYFSFVEKARAIGINVPIIPGIKPIAVERHLQ
VLPQVFRLDLPEALIREVEKCKNNKEIRQVGIEWSIEQSKELIAAKVPVVHFYSMGKSDN
IKAIAGAIF
>X1FFS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MVEPFRKILKSDKFFITAEIGPVKGTNVQKMIDNIEILKTKVDALNVTDNQSAVMRYPSL
GTCLLIKEHGGEPIFQITCRDRNRLSIQADLLFAFSRGIESVLCLTGDSLKMGDHPEAKP
VYDIDSVQLIQLIHNLNSGKDLSGNNLDGGVDFCIGASATSSADPIEPQLIKFEKKLKAG
IDFVQTQAVYDLDELKRFVDYSRNINKSVKILAGIVLLVSAGMAKWMNENIPGIFVPQNL
IDELAEVPKGESLSKGIEIAGNLIKRIKDEEICDGVHIMAIGKEEKVPDILKAAGILKD
>A0A7K3CYG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID337|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTFSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGDWIAHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSPDWESDTRHFID
KCRAGADYAITQMFFDPEEYLRLRDRVEAAGCATPIIPEMMPVTNVRQLDRLPQLSNAVF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHQA
>A0A6G8D4S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. HDW18|TrEMBL
MGYTHASHIDALNRNVAELSDINVSFEFFPPSSAQMEQTLWDSVQRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQNIVALRGDI
PANGGQPDMYAADLVALLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRSVAAGIEVEIIPGILPVSNFKQAARFAAQNHVKVPNWMVKQFAG
LEEDPVTRQLVGVSQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPPASSCAL
>X0Z1W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
GIVGQIMGAQALGLHNILSLTGDHTALGDCPEAKPVFDLDSATLIKLVREMVDSGSINGH
EIEHPPKLHVGGAANPNSDPMEAEILKVGRKAEAGAEFFQTQVVYDIDMTAEFLREINKY
NVPVFLGIFP
>X1LZP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
FFSIGVAGFPEGHIDCPDKETDSRYLKIKIDTGGEFVITQLFFNNKDYFEYLERVRKIGV
TVRIIPGIIPITNYQQLLRFCKTCGATIPQRVHEIFKPLDGDAEATYKAGVQFTVEQCNE
LLEGGAPGLHFYTLNKVDPTREILNKIKR
>A0A0F9IRB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
EIPRWLRKRLEEFHDDTDSLQAFTLDFLTDFTEKLINVGVPGLHFYTMNRTEPTLTICQR
LGLID
>X1LUX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MANSLFEEKLYSGEFLVTTEVGPPKGVDISEMVHHIDLLKGKVDAINVTDHQSSVMRFPS
LGGCLLVKERGGEPILQVTCRDRNRLALQADLLLAYSRGITNVLCLTGDSVDVGDHKEAK
>A0A7Y2UTY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp|TrEMBL
MPTPNVSFEVFPPRSVDAAFNLWDTAQALAPLSPRFFSVTYGAGGTTRDLTHDAAHVLRR
TSGLPVAAHLTCVGASKAETLEVADSFVKIGVKDIVALRGDPQDGADKFTPHPDGFADSC
ELIEALAEKGTFNIRVGAYPDSHPEAASEQANVEWLKRKFDAGADEAISQFFFEADSFLR
FRDACAAAGIDKPITPGILPVINWTSARKFATRCGTPVPQWLDDAFDAAIRDDRHDLLAT
ALCTEMCSTLIDEGVEDLHFYTLNRAELTRNVCRALGVTPQVTLEDVA
>X1PPX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
YSFELFPPKTEKGREKLPETAGILKELEPDWFAVTYGAGGTTRELTMDIVDELQKRLQIP
IMHHFTCVGHSKAELEAIIKKMKEKNICNILALRGDAPEGVEHWEPAPDGLEYCYQLIEL
IRSHDSFFSIGVAGFPEGHIDCPDKGTDSRYLKIKIDAGSDFVITQLFFDNNDYFEYLER
VRKIGVTVRIIPGIIPITNYQQLLR
>X1U6V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MTSSFKKALESGKFVVTSEVAPPKGTNLEKMRHHIELLKDKVDAMNVTDHQSSVMRFPSL
GGVLLTKEMGGEPILQMTCRDRNRLALQADLLFAASRGINNVLCLTGDSVILGDHKEAKG
VFDMDSSQLLAAIRRLEKGKDLGGNDLDGSVSFCAGAIVTPEANPIEPQLIKFEKKIEAG
>X1FE00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MGIGTFFRGLLSKDKEKKSLVRDSIFRPIRQPEWWQGDSEYHPAAYDEPVSDLERRLRNG
EFVVTSEVMPPLSANSDKLIQNINIVKPYVVAVNFTDCASASPRMSSMACCKVAHDNHAE
PVLQIAARDRTRSGLQSEIIGANELGVHNVLCISGDSARIGPAPMSNLNILDIDSIQMLW
ILRKMRDDGVYLDGRKMKNPPKLFLGAATSFTLEPELQAIRDHKKVNAGAQFFQTNLFFN
PNCLDRWLEQLDKREILNKVYILVGVI
>A0A3M7GHN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGIRNILALRGDPPRSDE
YNDPNNPLSEQDDSNKDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPSLVEKTAAGADFIMTQLFFDVEAYNNYERRLRSHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLGRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTL
NLEKVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSS
NRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPVNSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLKGEIEA
MPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSTDPIYGWGPKNGFVFQKPF
VELFLPSADWQRLKPILQSDDQVTYYAGNAAGEFQSSDENSVNPVTWGTFAGKEIITPTI
IEADSFKAWLEEAFGIWAEWQRVYQPGSESSRLLERTRKDCWLVSIIHHGYLEKGALWDG
LIAA
>A0A415V714|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF29-7AC|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSASFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A417XXV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides immobilis|TrEMBL
MTTGRGRALGDIIREGERSFSFEFFPPKDEAGEEQLWKAIRALEPYRPTFVSVTYGAGGS
TRDKTVAITGRIARETSLVPMAHLTCVGHTRAELEAILDAYVAEGVYHVMALRGDPQEGP
RAEWTPTEGGLNYALDLVELARSRGDFRIGVAAFPEGHPSAESLDVDADRLVAKAHAGAE
FAVTQMFFRAEDYFGLVERVRARGVDMPILPGIMPILNLNAIRRQGELIGTSVPDEIVER
ITAAGPDPDAVRSEGIKLAAELCEELLAGGAPGLHFYTLNRSKATLEIFEALRITV
>A0A2N4XM33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Uliginosibacterium sp. TH139|TrEMBL
MSKKLEFSLEFFPPATAEGVEKLRGVRTELAALGPEFISVTYGAGGSTRDRTLEVVREIR
AAGIDAAPHLSCIGSTQASIRDHLAEFREMGVKRIVALRGDLPSGMADPGEFRYANELVE
FIRKESGEEFFLEVASYPEIHPQARSYEADLKAFVNKVNAGADSSITQYFYNADAYFTFC
DAAREAGVRIPIVPGIMPIASFSKLARFSESCGAEIPQWMRRKFEGFGDDAESVRAFGLD
VVTGLCERLIAGGAPSLHFYTLNQTGLTRELCQRLGLA
>A0A425WMA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriaceae bacterium|TrEMBL
MRIDTILARKQTYSYEIFPPRGELPLQQAKEIAGELAQDHPDWISTTFSAGGHGNSQNVA
AICAQTQNELGVTALAHLTCMGSTKEDVDHYLDTLEHDGIQNVLALRGDKTASKEPKDFR
YASDLIAYIKEHYPSLCCGAACYPEGHIETKNMKESMEVMKYKQDAGADFFVTQLFFDNE
YFYRFRESCARSRIKRPIVVGIMPFTSQKQIQRIAFTCGASIPSAVIKRIIAAGDDRDKQ
AQAGLEYAIEQLQDLAQNGVDGLHIYTMNKLQVAHQIHSALKECGYLAA
>A0A496D1R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. OF04-13BH|TrEMBL
MKVIDLIRDSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNKKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIVHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A2W5MWC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis macrogoltabida|TrEMBL
MTTPLDSLAEARRAAASPLFANLDGDIGVSFEFFPPKTEKMEGQLWDTFRTLEPLAPRFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASRAEIDEVAQAYWDAGVRHIVA
LRGDVPGGGPYRAHPEGYANTIDLIAGLKAIAPFDISVAAYPEVHPDADCPQADLDHLKR
KIDAGGDRAITQFFFSPDAFLRFRDAAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMVALFEGLDDHPAARQLVAATVAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPAVINATEKAA
>A0A258ENI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium 32-66-9|TrEMBL
MPTPRISFEFFPPQSLDASFRLWETVQALAPLQPSFVSVTYGAGGTTRTLTHEAVSTIHR
NYRLPVAAHLTCVDATKTETLAIAEAYAAAGVTEIVALRGDAPKGAQRFVPHPLGFAHSV
ELVEKLARTGKFTIRVGAYPEPHPDAADSTADVTWLKRKIDAGATSAITQFFFSADTFFR
FRDACVRAGITAPIIPGILPITSWSGAKTFARRCGTSVPHKLDEAFTMAARDGREELLAL
TQCTQLCDNLVRGGVEDLHFYTLNRPYLTREVVRALGILPELVLEKVA
>A0A4S2N8P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ascodesmis nigricans|TrEMBL
MVHIKDKLAESISKKKPAFSFEFYPPKTGQGVQNLYDRMDRMHSLGPEFIDITWNAGGRL
SSLTTEMVNVAQSVYGLETCMHLTCTGMPKEKVDEALEAAYKAGCQNILALRGDPPREKE
KWEADPNGFRYAKDLVKYIREKYGDHFDIGVAGYPEGCDDGTEPELLMQHLKEKIDAGGT
FVITQMFYDVDIFLDWVQKARDIGITVPIIPGIMPIHTYAAFLRRANWTKCRIPPRWLEL
LEPIKNDDVAVRDIGRDLIVEMCRRILDAGIYQLHFYTMNLATATRMVLEGLDLIPSLEE
NLPPLPFRPSLGFNRKTETVRPIFWKHRKASYVQRTAEWDEFPNGRWGDSRSPAFGDLDA
YGIGLRGSNENNIKLYGTPASIKDVANTFVKYITGELQTLPWSESGITAEVNSIKDELIE
LNKRGFLTINSQPSINGVKSSHPVYGWGPAGGYVYQKSYLELFVSPEVLTDLITAIERDP
MMTYYAVNKQGHLKTNAPEGPNAVTWGVYPGKEIIQPTIVETISFLAWKEEAFKLGNDWA
GCYDQTSTGRHVIKSLMEGWWLINIVDNDFHREKKIFELFEGLNVPNLDEPIKIPDIVAD
LKNLDVSGDAKTNGTNGVPAN
>A0A127Z6T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporisorium scitamineum|TrEMBL
MPNGSDSPVPPKGDTSWKITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADL
GPEFVDITWNAGGRTSDLTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGC
RNILALRGDPPAGQSEWEPHAAGFTRAKELVEYIRDNYGDYFAIAVAGFPEGHPEAIDGP
EKELERLKEKIDAGADFIFTQMFYDFDIFAKWVKDVRAAGITCPIIPGVMPIQTYGGFQR
ATARFGTLVPQYFHDALDPVKDDDQKVREIGTRLVGDMCKKIVGTGLGISGLHIYTMNLE
KGSRMLLDYLGLTPSVNQVSPLPWTPSLTPKRREEKIRPIFWANRAKSYVNRTETWDEFP
NGRWGDARSPAYGDVDAYGVKLRYSNDEAKEMWGAPTSLDDVKALFENFCAGKVKALPWS
ETPVARETSVISDKLTRINQLGFLTINSQPAVDGARSDDKVHGWGPKNGYVYQKAYLEFF
VSPEDLDALIARIEADPQITYHAVNSQGDMRTNTNSEAPNAVTWGVFPHCEIIQPTIVES
ISFLAWKDEAYEIGRNWAKVYEPSSPSRKFLEDMFNSYFLVNVVHNDFKAADSIFEPFLS
TSEAASAVNGSLSGLGATVSDAAGRVANSISSLANGVSNGHTSAPAPTA
>A0A3R9YA96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MLVEYLTSLHEIYPVRREFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGK
ARDIQDFEFFLEQAKSANVQNLLLLTGDKLKEHHNGRDGQLRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVTSGKEFSPEITYFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALVAKVLIKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQT
EILKEKLIPTVPLETRGTSSWKNWYLAT
>A0A6N8A5Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium sp. RKSG952|TrEMBL
MTKPEISFEFFPPQTLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLPVAAHLTCVDASRQETLEIADTFARAGVQDIVALRGDPPKGQDRFVPHPEGFTSSV
ELIEALAETEMFSIRVGAYPDKHPEAGDMAADVEWLKAKLDAGADEALTQFFFEAETFFR
FRDACAKAGIDKPIVPGILPIENWKGARKFAQRCGANIPTWLEQAFEKAVRDGREDLLAT
AICTELCSDLIEGGVDKLHFYTLNRPELTRDVCFALGIVPKAELQNVA
>A0A8J3Y8X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirilliplanes yamanashiensis|TrEMBL
MRRVAAGTIPAVALGLPSRLPASPSIGDLIRGAEPTFSFEFFPPKTADGERLLWQAIREL
ESLRPSFVSITYGAGGTTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRNVIGRLAG
AGIRNILAVRGDPPGNPMGEWVQHPDGVLYAEDLVRLLREIGDFSVGVAAFPYKHPRSAD
TDSDTRNFIRKCRAGADFAITQMFFDADEYLRLRDRVAAAGCDTPIVPGVMPVTRMATIE
RSTQLSGAPFPPALLERFERLAGDEAAVRELGIELCSEMCRRLLDEGVPGIHFITLNRST
ATREVWQQLAATAPATAPA
>A0A143IZU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAQTANIQNLLLLTGDKLKEHYNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHHYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGFSGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
SGKEFSPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGLGRFIFKASFWENALVAK
LLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKALEQTEILKEKLIPTVPIETRGTSSWKNWYLATEA
>A0A8I1H456|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MSHISPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDIIDKVLHFSGKARDIQDFELFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQTLACVMPLTLGRANYMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVK
TGKEFTPEITRFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENSLVAK
VLIKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVAQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A7Y4XSI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclobacteriaceae bacterium|TrEMBL
MKVIDHIKKANGKTLFSIEILPPLKGENIKTLFDNMDPLMEFKPPFIDVTYHREEYVYKK
KEGGLLEKSSTRKRPGTVGICAALQNHYKVDTVPHIICGGFTREETENALIDLQFLGIDN
VLALQGDAIKTEPRFVPNPDGHKYASDLLGQIVNMNGGKFLDEDLENASPTNFCIGVAGY
PEKHFSAPNLKMDLKYLKMKVDMGAEYIVTQMFFDNKKYFDFVEKCREAGIMVPIIPGIK
PITTKAQSNILPTIFHIDLPEALSEEVDKCKDNAAVKQVGIEWTVQQSKELMKFGVPTLH
YYSMGKSDPIYKIAKQLF
>A0A7S7C299|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. WG16|TrEMBL
MPSGASTITDTYSLEVSVKDIGALTNAAPRILPGSDMFIPYLPGQTEAARLAAAQRVRRL
GFEPVPHLSARRIGSLEELQAVIARLVGEADVTRCLVIAGDPSTPKGPFADSVSLIETGV
FERSGIRTIGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDADIVMTW
LEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGNAGPDR
FVDRLVSRLTEAHGDVRLHFFPFGGIAQSVEWVAHYRSCEASQDRVSSVAAD
>A0A7X9J952|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MSEPSKFKALLASGRPLISDGAMGTLLHDRGVKLDTCFDALNIQQPALVAEIHRDYIEAG
AQIIQTNTFGANRFKLAQHGLAEKVTEINRAGVDLARKVVEASFKDVLIAGDVGPLGVRL
APFGRVQPEQAFAAFSEQICALTSGQVDLLILETFADLYEIVEAIRAAKTCAPDLPVLAS
MTFTRDNLTLLGDSPAKVARRIHAAGADVIGINCSGGPNQLLNLLKQMREAVPEGVFSVM
PNAGWPQQVEGRIMYPAGPEYFGDYALSFWREGASVIGGCCGTTPTHIASISSTVSKTNP
ASVQKIEVIRLKKDPSAAEAVALPPTQLASRLQAGKFAIAVEMDPPRGLTTQKLLAGASL
LAEAGADVIDVADSPMARMRMSPWAVCELIQRKVGIETTLHFPTRGRNLLRVQGDLLAAH
ALDVRNVFVVMGDPTSIGDYPDAMDNYDLVPSGLIKLIKQGFNAGLDHSGNEIGQPTHFF
VGCALNLNPQDLQGEIKNLRRKLKAGADFILTQPIYDIRHVTEFKQAYEASEGSPLPIPM
LVGLLPLASLRHANFLQQEVPGIDIPQTALQQMAAAGEHGAAAGVKLAAELAIQLKELAQ
GIYIMPAFGRYDHAAEIIEAIQ
>A0A2N2IY31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-16|TrEMBL
MKSGSRLERILTSGEFAVTGELGPPKNGNAEHVREKARLLKGSVDAVNITDCQTAIVRMS
SISAGLLTLAEGVEPVIQMTCRDRNRIGMQSDILGAAALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMVKTMRDEKKFQCGEVIKSHEPKLFLGAAANPFAGPSEQFRAARLAK
KVANGADFVQTQIIYNVERFARFMQAVRDLGLHKKVHILAGVTPPKSVGMARYMKSSVPG
MDVTDEVIKRMQGAKDKEDEGINICVDIIRQVREIEGVAGVHIMAIEWESAVPEIVSRAG
LATRPVFADEPFTLASSAVAPSSAIEIRTTAAGGEESDAVLAAAKVEAEKIIAAAKAEAA
QYRASATAGASGAGAVDQARIEIEEAGEDAMNEKERQMALDSVRLGLDALKKAYGLSDDQ
FDALVKFAGAEAILKREPLLAVPASPAPAPVAQAAPAAPAPVPDESAAKKAAEAAAADEA
KKAEAAKKAAADKAAAEAKTAEAAKKAAEAAAADEAKKAEAAKKAAADKAAEAAKKPAAP
EAKKAAPAASAAAVGAAELACEKTPLSERAAKVPEAS
>A0A0D6TKQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 316|TrEMBL
MKVTEHIHNANGKSLFSFEILPPLKGQNIQSIFDGIDPLMEFNPPFIDVTYHREEYEYKE
LDNGLLQKKIVKKRPGTVGICAAIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGNKYAGELVTQISNLNNGFYLDSDLQNSTKTNFCIGVAGY
PEKHMEAPSMDSDIHFLKQKIKNGADYIITQMFFDNQKFFDYVAKCRAAGITVPIIPGLK
PIVTKRQLNLIPHRFKVDLPDDLINEIIKAKDNDGVRDIGIEWCISQSKELLKAGIPVLH
YYSMGKSDNIKTIAKEIF
>A0A1J4Z086|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellaceae bacterium CG1_02_56_997|TrEMBL
MNQSPISFEFFPPQTAEGVEKLTVVRARLATLKPEFFSVTFGAGGSTQERTVDTIRQIHA
EGYQAAPHLSCVGSTRDNIRAMLLAYRQMGIRRIVALRGDLPSGMAGIGEFQYANELVSF
IRAETGEHFHIEVAAYPEFHPQAQSAQADLLNFKRKVEAGADAAITQYFYNADAYFNFVE
AASKLGVTVPIVPGIMPIMRFSQLARFSDACGAEIPRWMRKTMEGYNDDTEAVQAFGLDV
ITALCEKLIAGGAPGLHFYTLNQAAPCLAIIERLGLSR
>A8LG79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. (strain EAN1pec)|TrEMBL
MRGFELICEIEPPTRPDLTHARHQIGVLSPVADAFLIPDNHIGRATVSSIAVAHEVQTMG
GRSIACVNSRDRNLLGFRRDLLTAAAYGVEEFLFVHGDKPTAGNRTSDLTVRAMMDEARA
ASEDPVFADMPAFRVGAAAGLRPLPAWKRAADFLFVQVSYSVDALLRWRDAHPVELPVYA
GVMVLASAGMARRLAATIPDIDIPDDLVQAVERDQAAGVEAACDQVLRLRDSGAFAGVHL
VPVSRYRQVATRLEDLL
>A0A5C3FYU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudozyma antarctica|TrEMBL
MAASSSNSTPGAHAAAAPNPAHITAKIQQANARDAPFWSFEFFPPKTTQGLANLYSRIAR
MRANLDPSWIHVTWGAGGTTVEKSLELAGRIQKGRLDPATPLLSPNGQNGSEAGEEWQHE
SADACDVCLHLTCTNVQKASLDETLLAAKRLGIRNILALRGDPPRGEEYWVAADERFQHA
TDLVRYIRDSHGDHFCIGVAGYPEGHADYVDRDVQRDLAFLKQKQDAGAQYIVTQLFYDV
DRFLAWYKDARALGITIPILPGIMPIQNYQSFRRMTNLCKVQIPPLVLEALEPIKADDAA
VKEYGVALSIHMIGRIFLESDVRGFHLCSLNLEKSIERILDGLGWKTDVGALGEADVRLS
VVPAHLHLERTKNQMLSDRTGANTPRDFKVTTQEALKRTLARTSSSYQVPETTTWDEFPN
GRYGDSRSPAFGEMDGYGVSLKVPAADALRIWGHPVTLSDISTIFASYLEEKIACIPWCD
APLMNETLQIRDHLLALNRLGATRDAGKGWWSVGSQPAIDGAPSTDPVVGFGPAGGFIFQ
KAFVELFMSGSDKDALVEAIDAMGPHAQYTYFAGNTRGDFVSNLAEGEANTVTWAVFPGK
EIVQSTIIERDSFEAWREEAFGIWNEWAMLFLKTSASRQLIDSITNDRWLMTIVHHDYKD
AQALWKFLAQ
>M7WNN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosporidium toruloides (strain NP11)|TrEMBL
MVKISDKIKKAEREGRPWWSFEFFPPKTPEGWVNLYDRIERMQQLGPIFVDITWGAGGST
SEATTNFVKTAHSELGLETCMHLTCTNMPVEMEAYDSGCRNILALRGDPPRGVEEWKPTE
GGFNHAIDLVKHIRKNYGDYFCIGVAGFPEGHPQSESPEAEIRHFKKKVDAGADIVFTQM
FYDADVFIDWGRRLRAAGITIPIVPGIMPIQTFAAFKRRTDFAGTIVPKELWDLLEPIKD
DDAKVREVGTEYVADMCRKILNADLGIHGIHCYTMNLSRGTEMLLEEMQFVPTADRVKPL
PWRLSLTQKRRAETTRPIFWSNRQKSYITRTRDWDEFPNGRWGDASSPAFGDVDALLLAL
PHKPQDAIKLWGKPHSLGDIAALFARFCRGDLKSLPWSDQPAAKETTRIAEQLARINELG
FLTINSQPRVDGAPSEDPAVGWGPIRGYVYQKAYLEFFCPPELVEPLLELLGDTPSVTYH
AVNKQGDFRSNTAPGPNAVTWGVFPGAEVIQPTVVDSTAFQAWKDEAYELGWQWAQLYKE
TAPETYEVISRIFSDFHLVNIVFNDYRNNDEDAIFKPFFELAHQKGLSVANGH
>A0A4D7DL63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium larrymoorei|TrEMBL
MTNKDTDRHPSGDFKLSFEFFPPKSPDMDVQLWETVEELSRWNPDFVSVTYGAGGTTKAP
TLEAVRRMISVAGLATASHLTCVDASKREVHEVVDEFREIGVTHFVALRGDPSTGIGTAY
KPHPEGYENAAALVRGLRERGDFEISVSAYPEKHPESESDAVDIEMLKLKADAGATRALT
QFFFDNDVFERYMERVTKAGIKIPVVPGIMPIQNLTQLKRFAGRCGTTIPSFLDDRFAGY
DDNPAERAKVAADVAAEQIFDLQRRGVNEFHLYTMNRAPLVNAVLENVGFRPARKSAA
>A0A3B9KKY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MNITKLFDHKKTLFSLEIFPPKKDSPYNTIYNTLLRLRGIPADFISVTYGAGGSQAQRDK
TIEIASLILTTYHIEPVAHLTCVSLSRDEIIDTLERLKANQLQNILVLRGDITPTMTVKE
DFKHASDLAAFIKKYDSSFNLLGACYPEGHYQAESLEQDIENLKIKIDSGVDHLITQLFF
DNDKFYTFREKAERAGINVPIEAGIMPITNLRQIERTVALSGASVPAKLSRLFSRYSDNP
KALFDAGIFYATEQIMDLIDHDVRGIHLYTMNNVETATRISDAIQNVLEAENTPKNAA
>A0A3D0K1K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHIHDIFKRDRQTFSFEFFPPRTDTAMDALLGRMDDFAALAPSFVSVTYGAGGSTRQRTN
DLVVQLNESDRVDAIPHLTCVQHTHDEIETILHRYADAGISNILALRGDRPLDADYHPAS
DEYRHAADLVRHIKAFNESGAHRDPRGFGIGVAGFPEGHPETPNRLRQLEYLKAKVDEGA
DWITSQMFFDNVAFHDWCERCELEGIDVPLIAGIMPITGIKTMQRMADLAGGTNFPAKLQ
RRIRRYQDDDDAIRQVGVQWATEQCNELLDHGVAGIHFYTLNRSGATLEIFRALGARDTG
SLRQ
>A0A4Q0I4D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetivibrio mesophilus|TrEMBL
MNLLDLFQKKKPIISFEIFPPKLDTPIESIFSTLEQFKELKPDFISVTYGAGGSAKDRTI
EIASKIKNEYGIESMAHLTCVGHSKDEIDTLLKAIAEHNLENVLALRGDPPANQPDFDFS
KNAFQYANELIAHIRSKNDFCIAAAAYVEGHADSKRLKDDLFHLKQKVDTGVDFLVTQLF
FDNRIYYDFLDKTSSIGITCPITPGIMPIFKADQIKRITSLCGASLPAKLVIMMDKYGDN
DDDMRKAGIEYASNQIRDLIDNGVDGIHLLTMNRPKSTKEILINTGLIR
>A0A401G139|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfonema ishimotonii|TrEMBL
MRPPRGSDPEAVIEKAELIKNHVDAVNITDNQTSVCRMCSLSACIRLKTLGLEPVLQMVT
RDRNRIALQSDILGAASWDISNILCLSGDHQSFGDHAAGQNVHDLDSMQLLQTVRHMRDD
GKFLGGDDIKRPPQMFVGAAANPFADPYEIRVPRLAKKIAAGAEFIQTQCIYNLDKFEDW
MEKVVDRGLHEQVYILAGLTPMKSAGMARYMKNRVPGMDVPAEVVKRLADTPKEKQAEEG
IRICIESIQRLKEVKGVAGFHVMAIEWEEKVPEIVEATGLYPRPEV
>A0A1M4M900|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteiniborus sp. DW1|TrEMBL
MFIRDIFSKKRPVLSFEVFPPKKGLPVDIVYDTIEGIKVLNPDFISVTYGAGGSSKDRTV
EIASTIKNKYKIEALAHLTCYSSTKKNTEEILKELKRNNIKNILALRGDPPIDAHSEERE
YIYAKDLINHIKQVGGFSIAAACYPEGHIECKSLAKDIGYLSEKVHAGVDFLITQLFFDN
EKLFQYKNKLAKRNINIPVVAGIMPVLNKNQINRMVSLSGATLPKKFVRILDKYEHNPKA
LKEAGIAYATEQIIDLLSWGIDGIHLYTMNKPEVANTIIRNLLEIRDAVTEEKISNE
>A0A245ZLL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas mucosissima|TrEMBL
MTLSINQLEEARHALEAPLFADVAGDIDVSFEFFPPKSATMEATLWDSIGTLAPLGPRFV
SVTYGAGGTTRERTHATVARIARETAIPAAAHLTCVEATREEIDAVANEYWAAGVRHIVA
LRGDPPRAGERYAAHPGGYENAAALVEGLRRLHPFEVSVACYPECHPDSNDATADLDNLK
RKIDAGATRAISQFFFSPDVFFRYRDAVAAAGLDAEIVPGIMPVSNFAAVQRMSAMCGTE
VPAWMERLFAGLDDLPGARQLVSATLAAELCRKLYAGGVKQFHFYTLNRAELSFAICHLL
GVRAQADDGRAAA
>A0A829CL51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli MP021552.8|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6B4BAD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MNIKNLFRDKKVVFSFEIFPPKTTSSIQTIYNTLDDLKGLNPDYISVTYGAGGSVKNNKT
IELTSLIKNKYGIEAVSHLTCISSTKSDIEYYLREFEKNNIENILALRGDIPIGSKITGE
LNHANELIKHISDNGQFNIAAACYPEGHIEHKGLYREIESMKRKEEAGASYFISQLFFDN
NLYYNFQDEVRAANINLPIEAGIMPVTNKRQIERILSLSGASLPDKFKRIMERYEHNPEA
LRDAGIAYAVEQIVDLISTGVDGIHLYVMNNPYVAKRISQSIENILLTVNKNQFV
>A0A7W8QRW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis composta|TrEMBL
MTAPDPSGAPLGPAGAEPPAPAPQPPSALAELLTAADPVRPVLTAECPVVDTGGVAAVAA
HVARLAPYVDALNATDNPAAHAHASNVAIAIALKSLGVEPILQVVCRDKNRLALQSDIVG
AALHGVTAISCLTGDDVTAGDEPEARRVFDLDGVQLIRAAASLAHGRFLSGRPLEPPPPL
LIGAVENPAAPPFEYRVRRALKKAAAGARFLQLQICYRPEHLEAFCSLAASAGLTRGTAL
LPTIALVKGARALRFMNDHVPGIAVPEETVTRVEGASDQREAAYLLALEQARHALAQPGV
RGLHLADFRHDSSVARLASDLGLPVDRTAPGESALAR
>A0A6I2FJ63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. SYP-A9085|TrEMBL
MTGKDVPGLQEAASVIPAGTKINVTFLGNEDLEMRVAASKAVKDLGFVPVPHISARRLKS
QDQLEEFLGRLQEVGATEHVFSVGGDPAVPEGPYPDSLSVIRTGILQKYGVKEVSIAGYP
EGHPDIKDDVLWRHLEDKSAALKEQGLDAVILTQFSFDTDPVMGWIKDVRSRGIDTEIRI
GTPGPAGIKRLLGFARRFGIGANAMIVKKYGFSLTNLMGTAGPDRFVSDLSALLGKDEAA
GPVKLHFYTFGGLRATSEWVAEYRAAQA
>A0A7C8LMQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacteraceae bacterium|TrEMBL
MSLHLIHPAWGRPPETVTSGFSLEMTARDARALREVAGSVPPETPIAITFLPNETMDARI
ASAAEARALGFEPMPHLSARRIGSAEELQTIVERSVAEAGVRRMFLVAGDPPVPAGPYSD
TMGLLKTGLFERHGIRAIGIAGHPDGHPSMNAEECWRFLKLKCADIESRGMAPLIVTQFG
FDATPFLVWLKELRARGIGAPVRIGVPGPAKISTLLRFAAHCGVGASANVMAKYGVSLSR
LLGSTGPDRLVADLQRGLGPEHGPVRLHFYPFGGLERTVEWIRAYSGAH
>A0A3D2EF47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKITSIFEKEEITVSFEVFPPKTTTNYEAVEKAALGVAALKPSYMSVTYGAGGSTRGYTI
KIAEKIQKEQQVTTIAHLTCVGATKADIHAALGQMKEAGIENILALRGDRPKDFEGDPYV
DYHHASELVETIREYGDFCVGGACYPEGHPDAATKKEDILNLKKKVDAGCEFLTTQMFFD
NNIFYNFLYKAREAGILVPVIPGIMPITRANQVANAVRLSGCNVPERFRSIVDCFGDNPA
AMQQAGIAYATDQIIDLIANGVNHIHVYSMNKPEVAKGIYDNLSAIIH
>A0A3A8TTT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus sp. AB030|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTVEELAPLEPGFVSVTYGAGGSTRDRTV
DLVTHIKKHTGIEAMAHLTCVGHTRDELRDVLRRLDAAGIENVLLLRGDPPLGQATFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVGALKGRS
>Q98K87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVGRILNETSLTPAAHMTCVDAARHQVDAVIQEFAAMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A1F4A102|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_64_14|TrEMBL
MRSQENFPRTFSFEFFPPKTPEGKAKLRETWKQLGQLRPRFFSVTFGAGGSTREGTLETV
LEIRAAGHEAAPHLSCIASSREDLKAQLERYRSNGIRHIVALRGDLPSGLAMSGEFRYAT
ELVEFIRKEYGDQFHIEVAAYPEYHPQARTAQDDLRNFKRKIDAGADSAITQYFYNADAY
YHFIEECEAMGVTVPIVPGIMPIGRFSQLARFSDACGAEIPRWIRNKLEGFGDDTASIRA
FGLDVVTRLCDDLLKNGAPGLHFYTLNQAGLTSTIWQRLGL
>A0A1H5X3Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea lathyri|TrEMBL
MNAFRPSRHGSRRPKVSFEFFPPKTAEMEVSLWESVRRLEPLKPSFVSVTYGAGGSTRER
THATVKRMIEETGLKPAAHLTCVSASRDEVDDVIRAYWSAGVRHIVALRGDPAGGLGTTY
EPHPQGYNQTSDLVAGIRRVGDFEVTVSAYPEKHPEAASLDADIDALKMKVDAGATRAIT
QFFFDNDVYFRYLDKVRARGIEIPILPGIVPVQNFKQTAGFARKTGASVPQWLADRFEGL
EDDAATRRLVAAAVCAEQVLDLIDRGATDLHFYTMNKADLVYAICHLAGLKPERIAAQAA
AAE
>A0A0K1U702|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. CP1|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYREHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A3B9B8G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MPDKYTCEVEMNPPKQNSQKLEEDLATFAERFERVMESGFVASITDNAMGILHFQPHEMI
EELDLKPRENQVLIHLNTFHTKEVLDKILAFGKSHNITNFLCLSGDGSDKMHKLEPEELE
APEVPVTTSVELIRYIRKYYPEFHLGAAFNPYEPEEKEFAKLKRKVEAGAEYIITQPILG
RNPLVDRVMREYPDLPVVIECWMSKKVYLLSEVIGETIPEDTVYDGYEKLLELQKEYPDS
GNYLAMMGFKKTYPRVEELWKTRGAS
>A0A1H6D9L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea lathyri|TrEMBL
MTDSYLQPARSYGTLGSLIEGFSLEMTARDADVLAEAVGDLPAATRIAVTYLPGEEMAAR
VSAAASIRNYGHIPVPHISARRLTSVLELESFLDRLSIEASIDRAFVVGGDLRAPAGPYP
DAKSVIASGLLAKYGLSRIGVAAYPEGHPSISEHDLKLDLHTKLAMLRDLGHEGVVNTQF
SFDAGAILQWLEALRNDGVTATVRVGIPGPTTVKSLLRFAARCGVGASTAVLQKYGISLT
KLLSPVGPDRLLAELGARLDAERHGDVRLHFYPFGGLAGTARWAKTLVR
>A0A495JDZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora pisi|TrEMBL
MALGLPSVLPNPQPAIGDLVRGPRPSFSFEFGPAKTAEGERLLWQAIRELESLQPSFVSI
TYGAGGSTRDTTVAVTERIATDTTLLPMAHLTAVNHSVAELRHIVGRLAGVGVRNLLVVR
GDPPGDPTGEWVQHPEGVLYAEELVRLVRESGDFSVGVAAFPYKHPRSPDIATDTEYFIR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILPGVMPVTKITTIERSEQLSGAPF
PPALAARFARVADDPEAVRELGIQQTSEMCQRLLAEGAPGIHFITFNRSTATREIWQNLQ
VGVEV
>A0A0S9QWJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Leaf288|TrEMBL
MAHSIPVSPHAASLVNGFSLEMTGKDIAGLEEARETIPQGTKVNVTFLGNEDLEMRVAAA
KAVKEMGFVPVPHLSARRLESEAQLEEFLARLQEVGATEHVFAVGGDPAEPAGPYPDSLT
LIRSGVLQKYGAREVSIAGYPEGHPDISDDVLWRHLDEKVLALAQQGLDAVILTQFAFDT
APVMAWIDAVRARGIDAQIRIGTPGPAGVKRLLGFARRFGIGANAMIVKKYGFSLTNLMG
TAGPDRFVSDLATLLADDPKSGDVKLHFYTFGGLAATSTWAREFVAAQSSGARR
>A0A117LY79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium 38_11|TrEMBL
MFIKDKFIKKNKVISLEIFPPNNNMTLKQILDVIDELSIFRPDYISVTYGASGNANNNYT
VDIAEYIKEKYTIEAMPHLTCIGSNKEKINEILKLMIKKNLKNVLALRGDLPKDILSDST
NGTDYSYASDLIGHIRGSELPISVAAACYPEGHIEASSLNADIKNLKIKVDRGVDFLITQ
LFFDNNRFYDFKDKIVKNNINTPITIGIMPVTNVKQIRRIIALSGASIPLKLKTLLDQYE
NDNKGMFQAGIDYACQQMDDLNHLDVNGFHLYVMNKPEIARMIYKNMNW
>A0A1W6SME7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira lacus|TrEMBL
MESQKRFAPTFSFEFFPPQTREGIEKLRATRRQLAQLNPKFFSVTFGAGGSTRDRTLETV
LEIQAEGYAAAPHLSCIGSTSENIRSMLQKYHDGGIRHIVALRGDLPSGMAQWGEFRYAD
ELVRFIRKEFGSAFHIEVASYPEYHPQAGSAQDDLLNFKRKVEAGADSVITQYFYNADAY
FNFIEACEAMGIGVPIVPGIMPINKFSQLARFSDSCGAEIPRWIRKKLEGYGDDSASIRA
FGLDVVTDLCDRLLSAGAPGLHFYTLNSAGLTTTIWQRLGL
>A0A1P8PWD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. LK11|TrEMBL
MTNTILTQAEAALAHDEPLFADVGGDIAVSFEFFPPKTEKMDAQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTMDAAAHLTCVEATREEIDQVAQEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPDSVDKQADIDNLK
RKIDAGATRAITQFFFSPEAYFRFRDAAAAAGITAEIVPGILPVSNVAQTRKFAAMCGAC
IPDWMDRLFEGLDDHPGARQLVAATISAEMCRRLYAGGVKGFHFYTLNRAELAYAISHLL
GVRGKKAEAVAAA
>A0A420CLS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. AG363|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGIMVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWSIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A1W6ZIG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella genomosp. 13|TrEMBL
MTDNTTPALSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRT
LRNLGCDAAPHLSCVGATRQQLRDILHAYREEGVRRVVALRGDLPSGMGGDAGELRYARD
LVAFIREETGDWFHIEVAAYPEMHPQSGSPSADLQHFADKVAAGADAAITQYFFNADSYF
DFVDRARAKGVTVPIVPGIMPITNHSQLLRFSEMCGAEVPRWIRLRLAEYGDDKASIRAF
GLDVVTRLCETLLDGGAPGLHFYTLNSAEAPMGIWKSLASRL
>A0A1F3JZA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWF2_29_10|TrEMBL
MKLIDVINKSKTPYISFEILPPLKGQSIDKLFSILDVLMQFSPPFINVTYHRSEFVYKEK
AGGIFEKVAVRKRPGTVGICSAIMHRYQTDSVAHIICGGFSKQETEDALIDLDFLGVKNI
LALRGDPAKNEKHFEPEIDGHSYAIDLVKQIVNMNKGIYLDEDLKNAINTDFCIGVAGYP
EKHYEAANYQSDLRFLKAKVDAGADYIVTQMFFDNQKYFKFVDDCRAIGINIPIIPGIKT
ITNKKQIYSIPKIFHIDIPDDLYKDIFNSKDDKTVCEIGCDWSIEQSKELIKYGVPCLHY
YTMSNPEPIVKIIRKVF
>A0A259GNV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilales bacterium 39-45-7|TrEMBL
MKSHQEKLAFSFEFFPPKTAEGMDKLREARKELAKFNPEFFSVTFGAGGSTRDRTMETVL
EIQREGYQAAPHISCISSSKAEIRDLLHTYQSHGIKRLVALRGDVPSGEVSAGDFKYAAE
LVEFIRAETGDHFFIEVAAYPEFHPEAKTPTADLQNLKRKMDAGANSAITQYFYNSDAYF
RFVEQCDSFGITMPIVPGIMPINNITQLARFSNVCGAEIPRWLKMRLEEYGDDMASIRAL
GIDVVSELCETLMVWGVPSLHFYTLNQSATISTIINNIKD
>A0A0R2SNS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium BACL23 MAG-120924-bin60|TrEMBL
EETEYALIDLHYLGIDNVLVLRGDALKAEGAFKPEPHGHTYAIDLLKQVSDLNKGHYLHD
EVENSNPSNFCIGVAGYPEKHFEAPSLNTDIKYLKAKVDAGAEYVVTQMFFDNQHYFDFV
AKCRKANIHVPIIPGLKPIATASQLTTIPRNFHLNLPDDLVEAVEAAKTPAAVKEVGIEW
CIAQSKELMSQGAPVLHYYTMGKADATEKIASALF
>A0A317D769|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora acroterricola|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTEAGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATDTTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPEGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFEADDYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQASEMSRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGAPV
>V5MF48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis YBT-1518|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGSATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7W1V0M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTKHIENANGKTLFSFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYQFKE
LPSGLLEKKIVKK
>A0A417BWE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. AM42-5AC|TrEMBL
MKISELLKQDKVTLSFEVFPPKTSSSYESVARATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAKMVQKYKENGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCIGGACYPEGHVEAANKTEDILHLKEKVEAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVIAGIMPVTNVNQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQASLSEILG
>A0A657I1W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Crewe|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A836UHS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MIKDISFEFFPPRTEKMEQKLKQNIGALMRLSPRFVSVTYGAGGTTRYKTHEIVHKLINE
TKLNVAAHLTCINASLNEIDEVIENYVAVGVKHIVALRGDMKDLDQFIPHPQGFTNSIEL
VKHIKDKGGIKVSISGYPEQHPESQGITADINFIKSKIDAGADQIITQFSFENQNYIKYR
DTLVSQGINIPIIPGIMLIKSFNGIKNMSRKIGIKVPNWVDKIIEKESEETQKIIAEDVA
ITQSEELEKNGFEQLHFYTLNESEIMINISKHLGFHTKNNIA
>A0A1S2V9V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arsenicibacter rosenii|TrEMBL
MFQERIKSGESGVLLYGITPPKVGTTPERVAEIAQKTVERLATLHIDALVVYDVQDESAR
TSEERPFPFLNALDPLAFASGYLSSLNVPKIIYRPAGKFPAEELDSWLEELHERGFYPVF
VGIPAPDFPVKTSLAEAYALWRKHEDSSVIGAVTIPERHHVLQDEDKRILDKMVAGVSFF
VSQCVFNIDYARQVVEDLMRSCREQQINPPTVIFTITACGSAKTLQFMEWLGIHVPDALK
EELLASADMLEKSVKICLDIAEALTEFCMAQDVPFGFNIESVAIRKAEIEASVYLTNEID
QMLKQKGLRKPVSVVNT
>A0A2E2QRH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp|TrEMBL
MQSQKQFRRRFSFEFFPPKTDQGKEKLQNVRDQLAGVNPDFFSVTFGAGGSTRDRTIETV
LNLHRQGIPAAPHLSCVGGTRQEISELLDLYKEHGINRIVALRGDMPSGMGAAGELRHAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKLGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGNDSDSIRK
FGEEVITDMCEKLLRAGAPGLHFYTLNQAEPSISIWKNLGISDREKIAF
>A0A2S0UMU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmobacter aquarius|TrEMBL
MTVTPRISFEFFPPQTLDASFRLWETVQMLAPLKPAFSSVTYGAGGTTRKLTHDAVATIG
RNYGLNVAAHLTCVDATKAETLEIAESYAAVGVTEIVALRGDAPKGASRFAPHPEGFASS
VELVEALAKTGKFKIRVGAYPEPHPDAADPLADVTWLKRKIDAGATSAITQFFFNADTFF
RFRDACVKAGIDAPVIPGILPIVSWDGTRKFAARCGAQVPGALDEAFRLAARDGREELLA
LTQCTGLCTRLIEGGVEDLHFYTLNRPHLTREVVRALGISPEVALEKVA
>A0A2A2G499|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria sp. WN036|TrEMBL
MPIDPPHAGPAAALLRDFSLEMTGKDVPALEEAAAVVPAGTRINVTFLGNEDLGMRVAAA
RAVREHGFVPVPHFSARRLRSQGELEEFLAALAEVGAAEHVFVVGGDPETPEGPYPDSLS
VIRTGVLPRHGVRGVGVSGYPEGHPGIDDAALWSALTDKTAAIREQGLEPEIITQFGFDK
DPVLEWLAEVRRRGVDTPVRIGVPGPAGVRRLLGYARRFGVGTSAGIVQKYGFSLTNLLG
TAGPDRFLRDLAAGLDPAVHGQVLLHFYTFGGLRATAEWVREFGTDGGTP
>B0G1G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea formicigenerans ATCC 27755|TrEMBL
MTCKIRDILKDQTPQVSFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKN
TVSIASHIKDDFGVTSLAHLTCVSSTREEVHRVIDKLKEKNIDNILALRGDIPKDNAFPL
PNQYRYACELIEDIKQQGDFCIGAACYPEGHVETEHKKDDISNLKTKVDCGVDFLTTQMF
FDNNIFYNFLYRIREKGILVPVLPGIMPITNKKQLRRSMELSGTAVPQRFLAIIDRFGDD
PEAMKQAGIAYATDQIIDLIANGINHIHVYSMNKPDVAEAIMNNLSAILKVED
>N6W4J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas agarivorans S816|TrEMBL
MALSLQEKIEDTNQGVYLIGTTPPKIGTDKTQLKIIAEKLLARLHEIEYDGVIIYDIQDE
SSRTDKARPFPFKQTVDPREYSHLLRNLSAPDVITYKSVAQRGVEEFKGWLDETKNDYDL
KNVVLVGSPSSVGDIKLSLPDAYKTLAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGITPKRIILTFTPCGGDKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKQIA
>A0A2H1IRQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei CIP 102111|TrEMBL
MSTTLTHADPTLDSTFRDVAQRPPIGLSLTGRPRLRTSASAPENALETDLDNDPQRRLAL
SFEVIPPRSQAQAATLPALLAELDALDPDYLAVTSSAKSGWLHGTADFIRLVTATTHLRP
LAHLACTAGTRAELTTWIHHLLGVGVRGFLAIRGDFPDGATAVPDGHLPHADALVHLLRE
IESANTARLAAGRLGIGVAAYPSGHPESSGPDEDLDVLAAKQRLGADFAITQLFFDPRAY
ADLRRRSELAGITIPLIPGVLPVTDSRRLHTMSRLSGLPVPDDLLRRFDGAADPATARRI
GLEMTAEHIAAILAGGADGLHIYTFNDRATTLDLLEMLDRLGIRLDSAPAPVPASAPQPS
>A0A349D415|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MNKSVIEAIEQAEGTLFSFEILPPLKGADIEALYSGIDPLMEFKPSFINVTYHREEYVYK
KREKGFLEKISIRKRPGTVGICAAIKNKYGIITVPHLTCGGFSREETENALIDLSFLGIN
NILALRGDPIKSEARFVPNEDGHQYAIGLVDQVMQMNQGSYLDEDMQNKSKTNFCVGVAG
YPEKHAEAMSMKSDLKHLKEKIDAGAAYIVTQMFFDNQKFFEFVDKCRAMGINCPIIPGL
KPITALRHIEFIPKTFGVSFPEELSDQLENCSTDEQVRKIGTAWCLKQSQELKAAKVPCL
HYYTMGKSDSVKEIVSKIF
>A0A525J658|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp|TrEMBL
MTEVTPPISEGQRVLKQPAISFEFFPPKTEEMEKSLWDTIKRLAPLAPSFVSVTYGAGGS
TRERTHSTIARILAETELLPAAHLTCVGAARGEIDEIVRRYHDIGVRHIVALRGDPPGGI
GTAFSTHPDGYQTSPELVASIKRRYPDIEVSVSAYPEKHPESPDFDADIDVLKAKVDAGA
TRAITQVFFDNDLYFRYLDRVRARGIFIPIVPGIMPMHNFKQARSFVTRAGTSVPDWLAA
KFEGLDDDAETRKLVAATVAAGQVQKLNKHGVDTFHFYTMNRADLVFAICHLLGIRPSGA
QKAA
>A0A0M1J789|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromatium sp. WMS1|TrEMBL
MTNTYKDDLTFSFELFPPKTVDGLAKLKTEVAKLNKVQPRYFSVTYGAGGSTRDRTFTTV
DWLCSQGIETAPHLSCIGLQQQEILDLLNHYQKQSIRRIVALRGDLPSGMGSGLAGDLRY
ANELVKFIRKETGDLFHIEVAAYPEIHPQARNAQLDLQHFQRKVQAGANAAITQYFYNSD
AYFAFRDSCTRLNINIPIVPGIMPITNYKQLARFSDACGAEIPRWIRKRLENYQDDIEGI
QEFGHEVVTNLCQRLLDGGAPGLHFYTMNQATSVLNIWQALGLHS
>A0A345GUT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kordia sp. SMS9|TrEMBL
MKVTEHIAQSEGKTLFTFEILPPLKGQDIQSIFDNIDPLMEYKPPFIDVTYHREEYTFKE
LENGLLKKQVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKAEKEGHRYASELVSQIQDLNNGKYLDEELQNSSKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKAGAEYIVTQMFFDNQKFFEFEEKCRTAGITVPIIPGLK
PIATRKQLNMIPHRFHVDLPDDLIMEVVHCKDNKAVRKVGIEWCTQQSKELVAAGVPILH
YYSMGRSSNINAIAKEVF
>A0A1Z9T9K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiritimatiellaceae bacterium TMED266|TrEMBL
MKVTDHQKNAKGRTQFTFEILPPLKGQDIQSIFDSIDPLMEFKPPFIDVTYHREEYTYVE
RENGLLEKRVIRKRPGTVGICAAIQNRYHVDAIPHILCGGFSQEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPSKGGHAYAKDLVVQIKNLNQGQYLDEEILNSSPTDFCVGVAGY
PEKHAEAPSLDNDIHFLKEKIKAGSDYIITQMFFDNQKFFEFETKCREAGINVPIIPGLK
PLATLKQLNLIPQRFHVDLPKDLIDAVVKAKDNTAVSEIGVEWCIQQSKELKQHGVPFLH
YYSMGKSKNVKKIASALF
>A0A2N2FCS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-7|TrEMBL
GRGAREAAQEKAMALAKQAAVGGKIQALTVTDNPGGTPAMSADFMGSEILKMGIEPPVHF
TCKDKNRNQIESQLYALDRAEVRNLLVMSGDYPVSGYQGRPAPVFDLDPIHTLQLVSEMN
RGLEYPGIKGTVRHQPSDFFAGAVVSPFKATEAEQVIQYYKLKKKIHAGARFIVTQLGYD
VRKFHELILFMKLNGFDIPLVGNIYILPYGAAKMMNRNDLPGSVVTDKLLADLDRERSDP
DKGEGARILRAARMYAIMKGMGFSGVHIGGHNIKYEQVEEIIRQGEELTAQWTGLIRYFD
YPMENGFYYFERDPETGLNKETPEKRQGRPLDAEIECTYGFSRLSHKLMFEPGKKLYGIM
NRLSRKVAGTKMEGLFHKLEHLTKVMLFDCKDCGDCALIDVAYLCPMSQCPKNQRNGACG
GSFKGWCEVYPGKKQCVYVR
>A0A841BP25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allocatelliglobosispora scoriae|TrEMBL
MTSFDLVCEIEPPTRPDLRHVRHQIGVLAPVAHSFLIPDNHIGRATVSSIAVAHEVAAMG
GRSIACLNSRDRNLLGFRRDLMTAAAYGVEEFLFVYGDKPTVGDRTSELTVRAMIEETRQ
LADDPAFAGCPPFRIGVASGLRKVPSFKKTADFMFAQMSFSVEALLRWRDSVSLDMPVYA
GVMVLASPGMARRLAATIPDIEFPDALIERVAADPRAGVDAAFEQIEALRESGAFHGVHL
VPVSRYREMALRLEGR
>A0A7H2QSJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIEDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKAFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGYAGIHLSACHKPEEQMLLESYVEQYRHLELKALEELWNSLWQVT
TGKEFSPEITYFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGIGRFIFKASFWENTLVAK
VLLKTEVLSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEVLKEKLIPTIAIETRGTSSWKNWYLATEA
>A0A840C4X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actibacterium naphthalenivorans|TrEMBL
MPAPRISFEFFPPQSLEASFRLWDTVQTLAPMKPEFVSVTYGAGGTTRKLTHDAVTTIHK
NYGLNVAAHLTCVDASRDETMEIVNAYAAAGVTEIVALRGDPPKGQSGFTPHPDGFADSA
ELVAALAETGKFNIRVGAYPDPHPEAKTGGDDVRWLKKKIDAGASSAITQFFFEAETFFR
FRDACEKQGIDAPIIPGILPIDNWSGVRKFAARCGAHIPAWLDDAFEAAARDGREELLST
AIATELCSELIDGGVEDLHFYTLNKPHLTRDICHTLGVQPGMILENVA
>A0A841I132|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinobacterium chartae|TrEMBL
MILRNKLGRQFVVTVELDPPRGPDPSATLEEARSLRGLVDAVNVSDSPMANLRMNSVTAA
HLIRRETGLEAIAHLTCRDRNVLALQSELLGAQALGVGSVLCLYGDPPSRGDHPEARGVF
EVDTDGLIRLVAGLNAGRSCAGRDLGSATAFNIGVALNPCAADLERERERLHAKVAAGGT
FAQTQPVFSAADVERFLEATGPLPIPVLFGVLPVRSVKMAQNVGRWAKVPEALLKDLEAR
GLEAGLAWAARLVSDLRALGVDGVHLYPLGKSAAVGRVLEAARV
>F3UF49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis SK1056|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLQIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT
DLIEYIKTEAPHFNIIGACYPEGHPDSPNQISDIQNLKKKVDVGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF
>A0A2L0I2X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ACNIH1|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A0B8YGG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter glucosidilyticus|TrEMBL
MKITDHIKNAKGKTLFSFELLPPVKGQSIQWIYDAIEPLLEFKPPFIDVTSLREDYIYKQ
KENGLLEKLSYRRRPGTIAICAAILNKYKVDAVPHLICGGFTKEETENALLDLQFLGIDN
VLVLRGDARKADASFIPTPGGHAYATDLLAQVKNHNAGKFLHEDVESEYKSDFCIGVAGY
PEKHFEAPNLSTDFKYLKKKVEMGADFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLK
PISALSQLVNLPKIFHIDLPEDLCEAVQSCKTPKDVKQVGTEFMIKQCKELMDFGAPVLH
FYTMGRPEQTRQIAEAIF
>A0A0D1XNZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala mesophila|TrEMBL
MHISKKLALAHEKKKPTYSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
TLTLEMVNAAQSQYGLETCMHLTCTDMEKSQIDQALEHAFKSGCTNILALRGDPPRDQEK
WEAKEGGFQYAKDLVKYIRSKYGDHFDIGVAGYAEGCDDHRDVDLLVKHLKEKVDAGATF
VVTQMFYDVDIFLNWAQKCRDSGINVPIIPGIMPISTYASFKRRADWTKCNVPPAWSEAL
DPVKNDDSAVREVGKDLVAAMCQKLLDAGILHLHFYTMNLAQSTRMILDELSLTPSMSGT
PLEKPLPWRQSLGLNRRDETVRPIFWRNRNTSYVARTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANIKLWGRPKSLRDVTVLFTKFVDGSLDRLPWSEGAISAEANSIKSDLL
KLNKHGLLTINSQPAIDGVSSSDPVHGWGPAGGWVYQKAYLELLAFPSIIDKVIERLEAH
PNLTYYAVNQKGRLLTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WSKCYAPGSGSRKLIETIMDECYLINIVNNNFRETHEIFEIFEGLEPQDIDKVFEDEVVD
VTNNSKELVNGQASSDAVKGTL
>A0A2G7G1W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus arachidicola|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGTT
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEARVLGIRNILALRGDPPRSEE
YNMHGEDDSNRDFTFAVDLVRYIRQKHGDYFCLGVAAYPEGHPVDSFQDVQDPKSDLPYL
VEKTQAGADFIMTQLTYDIEAYTRFENMLRTHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVQIPPQILSKLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLRGFHFYTLNLEKT
VSFILERCDLIPPYSEDFDAIEEGGDISAMDGAQLRSLTRRRASSINSLPHNRVIVDKLH
ASEVSSKASVSHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSS
GLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFF
CPSKDYHSILKPLLQKHGHEKLAWFAANIKGDFESSLPAQTSDADPIEMNPDNVNCVTWG
VFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNDVKDDVWLVCVVG
QEFGAGTELGSEEEEDEKKFMWRVLLNAKQ
>G9YI86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeroglobus geminatus F0357|TrEMBL
MSTVKNTVNRQPPVLYIKEFCRMKIIDILNSKNVTLSFEVFPPKTAAAVPAAEKAALDIA
ALRPDFMSVTYGAGGGTSDFTVHIAEKIKGVAGVEVMPHLTCISSTKEKVRTMLESFRNG
GFETVMALRGDIPAEGIPHRDYGYASELVADIRKYCPGMCIGGACYPDGHYEAPNKDADI
ENLKKKVDAGVEFLSTQMFFDNAVFYNYLYRLRAEGITVPVLAGIMPITGAKLLGRSVTM
SGTTVPARYKAIIDAYGDSPEAIKQAGIIYASEQITDLLANGVKNIHVFTMNKPDVAEAV
YSNIKPALDYLNGN
>A0A2N1SKN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetae bacterium HGW-Spirochaetae-2|TrEMBL
MKVTEIIAQAKGPLFTFELLPPLKGHTMDAINETIETLLPYNPAYINITNHQMEVVYVDR
PDGLVERRTTHKRPGTVGLAAAIQYRYGIPVVPHLICGGQTKEQLEDQLVELNFLGIENV
LALRGDPPHGERRFIAAKGGYDHTDGMVAQISAINRGEYLDPTLRDPVATSFCIGVAGYP
EKHAEAPNYNHDITMLKRKVDAGAHYIVTQMFFLNERFFEFVDQCRAAGIEVPIIPGIKP
IQRRSDLDLLPQTFRVDLPVTLVDRIERCKTAADIRKVGVDFCTAQVAQLLEAKVPGVHF
YTQGRAEPIANVVEATYPKGILR
>K1UDQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|human gut metagenome|TrEMBL
DKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKELENGLLTRQRV
RRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISNILVLRGDKAKE
DRQFTPTENGHAHATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACYPEK
>A0A2V5E5U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. RV120224-01b|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTIAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DGDKHQEAMHWMRRQATPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETVQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQARIHTLDQWAPA
WRASWQMPGLPAVTFHPPQAGWRQGESRVDASLTEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPLWSTPVGAQVLHKVERAVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAPQTP
RRLSPQPTPRSQPES
>A0A8H3GWM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKLTEKLSTYRSDTPYFTFEFFPPRTDQGYSNLLTRISGLASLKPIAASVTWGAGGSTRD
RSLDLAGFCQADNGLDTILHLTCTNMEKGTIDEALTTAMGRGVSTVLALRGDPPRGGEYW
IPTDPRFQHAEDLVTYIKQHPTFASHFCVGVAGYPDGHSEGGSEEEQLVHLKRKVDAGAE
FIITQLFYDVEKFKSWLRNVRSTGITVPVIPGVMPLQTYATFTRMTDLCKATVPLHIQAN
LDAIKHDDQLVKEYGVSLAVSMIRSILVDGDVKGVHFCTLNLEKSVRKILDELGWTHESF
HHNQIIIDANQSPHILPSPADAPHPTTFTISPSEATQHATTSLAEHTRTGTLRTAAEAID
SGWDDFPNGRFGDSKSPAFGLIDPWDGGGLGVPAHVAIAQWGRPTTEQELSDLFLAYLNH
TASTTPFSPEPLSDESATILPHLVSVTKRGLWTVASQPAVDGAPSGDPVIGWGPKDGRVF
QKSFVEFFATETDLEKVAQAIEDSGDGWLTFFAGNNEDGFLTNIPDSGSNVVTWGVFPGK
EIAQPTIIDRDSFLAWKDDAFMIWHDFGLCYPPGSPTRKLLENVIKTRWLVNIIHHDYKN
SNALWDFLAKYLE
>A0A8C9IPV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piliocolobus tephrosceles|TrEMBL
MVNEARGNGSPNPCLEGSASSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDLCVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKAHPERERDRDSVTLGP
DALRWSHSCPTFLLHSATSLGNLTLLHVSPTPASTPPDDGS
>A0A828PVI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus pleuropneumoniae serovar 6 str. Femo|TrEMBL
MSYAKEIDNLNHTLADLNGNINASFEFFPAKNEKMEMLLWDSIHRLAPLKPKFVSVTYGA
NSGERKRTHSIVKRIQQDSGLAAAPHLTGIDANPEQLRIIAQDYWENGIRHIVALRGDEP
AGYAKKSFFAKDLVKLLKEVADFDISVAAYPEVHPEAKSAQSDLIYLKQKVEAGANRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVTNFKQLQKMAKITNVKVPHWMHKMYEGL
DDDQTTRNLVAASIAMDMVKILSKEGVKDFHFYTLNRSELTYAICHALGVRPT
>A0A7H9B001|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygotorulaspora mrakii|TrEMBL
MHINELYNGRKNPSLSLEFFPPKTEMGKRNLLERMERMSALDPLFITVTWGAGGTTADKS
LELASLAQKVSNLPVCMHLTCTNMDKSVIDDALEKCQNAGIKNILALRGDPPIGEDWTSS
QTKNSEFKYAVDLVRYIKNKYGSEFCVGVAAYPEGHCEGEAEGQEQNPSKDLPFLKEKVD
AGADFVITQLFYDVDKFLDFEKLFTEKISNQIPLIPGLMPINSYLLFHRAAKLSHASIPE
DILKRFPQDIQLDDNKVKSIGIEILVEMVDKVFKETNGRIKCFHFYTLNLEKAIAQIVTR
SKTLNYILEDDSRDDQDIDADGDVVLDEEINMNNQRVLDETRKRRRHSSNVSMEIASNRI
IIGQDRNKNIGAPSRKVVISISKGSGTLGQCATWDEFTNGRFGDARSPAYGEIDGYGPTI
KVGNKRAYELWGAPKNLEDLKEIFIKYLENSIDNLPWCDLGLSAETALIQEELIQFNNRG
YLTLASQPATTGSSSNDKIFGWGPPNGLVYQKAFVEMFVSKQRWKSHLEKTLQNYGREKL
SYYVGDALGNFESNLEPESSNVVTWGVFSNSQIIQTTIISEESFKAWRDEAFSIWLEWAK
RFPRNTPTNSFLRQMHGDCYLVSIVHHDYVQSEELWEILLGL
>A0A8H6MDA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tulosesus angulatus|TrEMBL
MRISQKIEQSAKDGKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPREKVDIALKGAYTDAKESGCRNILALRGDPPM
GKEEWEAVDDGFVHGIDLVRHIRKHYGDYFDIAVAGFPQHMNLPDAERDQEIQWLKEKVD
AGVNFIFTQMFYDVDLLSAPAGITIPIVPGINPIQTWNGFIRATSLSQTVIPQALMDILE
PVKNDDEKVRELGIKIVADLCRKILDSGLGIKGLHFYTMNLERGTKMLLEELNLVPRIET
IKPLPWRQSLTPTRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELDGY
GVWIKQTKENALQLWGTPTSIEDVSSLFSKFCTGDLSALPWCDQAPSMETSVIAQQLAKM
NALGFLTINSQPAVNGARSDDKTFGWGPSNGYVYQKAYLEFFVHPELLQLLLKQIERDNN
ITYYVINKRGDLQTNTHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAFELGSQWA
KLYESDSPAHKLIDEIMETYSLVNVVQNDFHNTDAIFEPFWKAGAEWEALKAKSANGSAH
GANGKPVVNGVQRRLGPV
>N6WXS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter nanhaiticus D15-8W|TrEMBL
METQKQFKRRFSFEFFPPKTDQGKEKLQGVRDKLAAVNPDFFSVTFGAGGSTRDRTIDTV
LSLHEQGISTAPHLSCVGGTRESIAELLDLYKENGINRIVALRGDLPSGMGSAGELRYAN
ELVSFIREHSGDTFNIEVAAYPEFHPQARTAEEDLKNFARKIEAGANSAITQYFFNADSY
FYFIDRLETMGITIPVVPGIMPIVNYSSLVRFSDMCGAEIPRWIRKQLDAYGDDSESIRK
FGEEMITRMCEKLLEAGAPGLHFYTLNQANASLNIWNNLGLANRDKIAF
>A0A2D7KVI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MNNKLKKKLEKKEFVFTAETSPPDSTEIVDITERISCLKNLADAINVTDGASAKSHLSSL
VVSSIVQSFGIEAIMQITTRDRNRIAIQSDLLGAWTLNIKNILCIYGDQVHTGDQPETKE
VRDLDTLEIAKTADYFKKEKKFPSGRLIKSAPDFFIGGADTPYDIDDKFDCKNLEKKINA
GVNFFQTQYAFDFLTLNKYMNRLNDYGIPEKSFYLIGLGVIKTAKSAKWMNKNLYGINIP
ENIIKRIENSKNQEEEGKKICIELIEQYKGIKGIHGVHLMGYHQEQQIAEVIKYFKN
>A0A1U7CJK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paludisphaera borealis|TrEMBL
MHILDIFETNPTTFSFEFFPPKTDKASADLFETMAHLQALQPSFVSVTYGAGGTTRERTH
DLIVRIQQETNLTAISHLTCVCHSEAELEAILERYAASKIENILALGGDPPRNLQGYDRA
NDAFQYADQLVRFVRSRLGVADSRGFGVGVAGFPEGHPGTPNRLLEMDNLKRKVDAGADY
ICTQLFFQNADFYDFRERCDLAGIRVPILAGIMPVTSKENLARIAELALGARIPARLLRA
VERCGDSAESVAKVGVHWATEQCRDLLDNEVRGLHFYTLNRSDATRQIYDYLGVKDSQAL
ARRAAV
>A0A502G943|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ewingella americana|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASREELIQIAQDYWQSGIRHIVALRGD
LPPGGGKPDLYATDLVHLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPHWMTAQFE
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEAAAPI
RAAV
>A0A1E9VXZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria sp. HMSC077D05|TrEMBL
MSYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHSIVKRIQQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DNDQATRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A4P6EG22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium protaetiae|TrEMBL
MTLADDLQRTSPIVPFSFEVYPPRTPASTLALHDTLTRLAEAGPRFISVTYGAGGSTGGA
SLEVLRYLRTHTEVEPLAHLTCVGNTYTGAAGLIREFLDAGIRSFLALRGDPPVGAEEGD
SFLGDLESAAQLVQLIDRVQAERAPYAEAGINGLPRAARVVPGEPVEIAVAAFPNGHPRS
RHPREHIDALLAKQAAGATFAITQLFFHADDYLGFVDRCRAAGVTIPILPGIMPVTSPAR
LARVLALTGHEVPAELSIDLQIEPDPARQRAIGVAYAARLAAEVVAGGAPGVHLYAFNSH
ETVLAVLSEAGIPTTIQKETAR
>R7GLM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catenibacterium sp. CAG:290|TrEMBL
MSVTYGAGGGTSAHTVALAKDIHEKYDVEVMAHLTCVSSTREHVESMVEQFKENGIENIM
ALRGDIPKDGQVGEDYQYACQLIKELKEKGDFCIGAACYPEGHVESPSIKEDIQHLKEKV
EAGADFLTTQMFFDNNVFYNFLYKIKEAGINVPVVAGIMPITNAKQVSRAVQMSGTSIIP
YRFKMMVDAFGDNPEIMKQAGIIYASEQIIDLIANGVKHIHVYTMNKPDIAEGIMNNISE
ILK
>A0A1M3D362|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium 41-46|TrEMBL
MTVIEKINRAKRPLFTFELLPPLKGHSIERVYRTIESLLEFEPAYINFTSHRNEVQYIES
PDGTLEKRFSRVRPGTIALSAAVKYKYNITVVPHLLCGGFTREETENALIEMNFLGIEDV
FALRGDPPKGSRSFIPERGGNENAKALVEQISATGRGEYINGHVDSSSPSKFCIGVAGYP
EKHFEAPNMEIDLLNLKSKVDAGAHYIATQMFFDNAAFFRFRDNCRKIGIDVPIIPGIKP
ISALNDIRLLPQTFHIDLPADLYNAVAKCKTDEEAREVGIEWTTMQTKELIKEGVPGIHY
YTLGRSDNVARIVKASF
>A0A351R401|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp|TrEMBL
MKVSEILKKNEVTISCEIFPPKQGAQLQNYKAIAAEIAKLKPAYISCTYGATGGTSDYTV
EIADAINSYGVPAIAHLTCVSSTREKVHTVIHELKERGIENILALRGDIPTNTDFPLPDQ
YHHAIELIREIKEAGDFCIGGACYPEGHPEAANMNEDLDHLKEKVDAGCEYLTTQMFFDN
NIYYRFLYKALAKGIDVPVTAGIMPVTNATQVKRTISLTGNLVPAKFLSIVDRFGDNPAA
MKQAGIAYATEQIIDLIANGVNHIHIYSMNKPDVAAAIMNNLSQIYVREQA
>D8NA90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia solanacearum CMR15|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSLLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILDTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRKEMNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>A0A1B9JRQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPNVQPKNDF
RFASELVSFIKENGDFNVIGACYPEGHLETSTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYTFLDKAHDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQDVDGIHLYTMNNSYIARRISEAVSTLLAVPKSA
>A0A435WT19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.002.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A7Y3GGE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MSTDENGFKSGSNLEKILRAGHFAFTGELGPPRGTNAKEVKEKAQHLKGSVDAVNITDNQ
TAMVRMSSWAACLLILQEGLEPNFQMVCRDRNRLAMQADILGAYAHGIRNMLCLSGDHCM
FGDHPTAKGVFDIDSMQLIHMVKQMRDESKFQGGADIEDPPKIFIGAAANPFADPFEWRV
HRLAKKISAGVDFIQTQCIYNMKKFREWIKQANDMGITEKAYILAGVTPMKSVGMAKYMK
SKVPGMDVPDEVIKRLQGAGKGKVADEGIKFACEQIEEFKEMKGVAGVHLMAIEWEHKVP
EIAEQARVLPRPQVD
>A0A7Y3CFQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKLKDALKKKKFVVTSEVQSPIDREPEDLVRSLASVSGRVDGVSLSEVELEGFVGDTIRT
CELLNKSQLEPIYQTTTRDKNRLQLQNDLVEAHNSGIDNLLVFTEDYRITGDSLQEMMFF
HVDAGKLKSVLEHMREGRTVEGDSLKSKADFLLGSGVESSWGKSVPDLEMKEMEEMTKLG
TSYFLTTPIFDVDRFEKFLKQTQTFGVPVIAEVMILRTVGMARFLNRHLKSGMVPDWIIQ
KLAREPDKQKASIEIFTDIVTGLKDLCQGVHIITIGGEEKLKLYLDSAKLK
>A0A4W5LME5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hucho hucho|TrEMBL
ATTPSSATSAILTAKSKLPACQTDAGESGKLSPILSQEFAMTERNRTFSFEFFPPRTAEG
VAKLRTTRQQLAQFKPEFFSVTFGAGGTTRDGTLSTVLEIRNEGHAAAPHLSCIGSTRDN
IRAILNEYRNHGIRHVVALRGDMPSGMVEAGEFRYANELVSFIRAEHGDHFHIEVAAYPE
FHPQAKSAEDDMNNFVRKVKAGANSAMTQYFFNADAYFRFVDEAQARGVDIPIVPGIMPI
ANFGQLCRFSDMCGAEVPRWLRLRMQSYMDDTASIRALGLDVVTELCDRLLANGAPGLHF
YTLNQAGTVSTIWHGGFLWGSANHRRGCSEIEMGNRQRGSLLELLEHETGFHILHPRLLQ
QVIHHKAREVFQVFKIDLQQVVHFTGHGVAVHHFRPALYGIHETLQMGAAAFL
>A0A4R6U028|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiopseudomonas denitrificans|TrEMBL
MNRLQQALDAGRFVCVLEASPRFSPTQRAALEQILQHGQLAGWPLLPAFSDRVGLQPGPG
PLEAAGTLNNPTPALLHFSGKDREQSDLLQQIRAMRALGLKQLLLLSGDRLPGHQPDQTP
VRYLESVPALQITRRHCPDWLLGAALNPFKYCEEESQAQYLKGQKKLLAGADFLTLQLGF
DADKHLEAHAWMRRQPASKPVLACVMRLTVKRAAVLQSVPGILITDSMRSFLQHEQKLSE
TAASERSLERLALQIIGLQLMGYAGIHLSGVHSLEELLALEQAIIRLRDSLTSLEQWQLR
WQASWQLPGTAAVCFTPPATARWTPGQPGVTASRKELLRYRFFYAVHEQLFDRNGWPGRA
FGWCMAQPVWKKPWPARTLHAVERAIKRPLLGCDTCGTCRLQDTLYVCPETCPKGLANGP
CGGTRQNRCEFGDRECIHSIKYRIAKSADQLPVLAHNLIPCIQADERHRSSWPGWFEADQ
PGQNDP
>A0A1W2TAZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rosellinia necatrix|TrEMBL
MHINDMVADAERTGEPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFVDITWGAGGRIA
ELTCDMVLQAQTFLGLETCMHLTCTDMGEEKVNDALQRAYKAGCTNILALRGDPPREKEK
WEAAEGGFHYARDLVAHIRKKYGNHFSIGVAGYPEGCDDNKDEESLLDHLKEKVDMGGTF
IVTQMFYDADNFIRWVGKVRERGITVPIIPGIMPIATYASFFRRANHMNCKIPEKWMAAL
EPIKNDDSAVREVGKILVAELCRQIMSAGIVHLHFYTMNLAQATRMVLEELDWLPSSQRP
RQQPLPWKQSLGFGRREEDVRPIFWRNRNKSYISRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNELNRKKWGEPQSIDDIASLFVRYLQKELDSLPWSEAPLSGEAVSIKDDLIK
LNSRGFITINSQPAVDGVKSTHPIYGWGPSNGFVYQKAYLELFVHPKLYGEVVRRIEGHE
TLSYYAVNQAGAFTTNAPSEGPNAVTWGVFPGKEIVQPTIVESVSFLAWKDEAYRLGNDW
ARCHDANSPSRALIEGIMNKWYLINIVNNDFHDSRTVFELFDGLEVPKEDRDTPSSIPVT
HTNGINSTHNEINGVAALT
>A0A1S7ULE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rosellinia necatrix|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
ATKSLELAEICQRELSLTTCLHLTCTNMSRKMIDNALEDAKALGIRNILALRGDPPRAAE
YQHADQDPENTIDEGFVWALDLVRYIKSKYGEYFCIGVAAYPEGHADESHPLGQSLEHDL
PYLVEKTLAGADFLMTQLFFDTDAYSKFEQRLREHPSGVFKTIPIIPGLMPIQSYQMIRR
TTKLSHARIPDEIMARLDAVKKDDEKVKNVGVDILCEIVEQVKEIKSRTPGPKGFHFYTL
NLEKAVSFIVERGHLISSTPEEEEAVVDDGPLPDIPSLAINGAVSSRHLHDLSRSRRQST
IGSEPRNRVIVSERTLSNPEYEASQADAGLMAGAINTRANTLAISEGEGVLGREATWDDF
PNGRWGDARSPAYGEIDGYGPTLHVTQAQAIALWGHPKSLEDVNALFVRHLQGELNAIPW
SEEEVHEETGTITDQLIQLNQRGLWTVASQPAVNGFRSEDLTFGWGPRHGFVFQKAFVEF
FIPAAAWKTLHGKLMSPEIRNMVTYYAANAAGDFVSSDSAGGGSASDAAAAADANNEDYG
ESSTNAVTWGVFPGKEIVTPTIIEEVSFRAWADEAFGIFSEWAQVYGKGHESERLLEAAR
ADCWLVNIIHHDYMDKEALWDLLLK
>A0A7C4IX62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MTLQEKIRSGKFVVLGEFEPPKGADFTLLSKSANLSRGRLDAVVVPEMANAVLKASSLGG
CAFLQREGLETVFQVCCRDRNRLALQADMLSAAALGIKNLMAVPGEDIRFGDHPQARTVN
DLDLLGLLEAAQKLRNGKDLSGIELRGSAGFCVGSTLDTGAPGGLLNIEIENLKRKVDLG
VEYVVTNPIFDLRRFEQFLKRIDVKPLAVIPTVLLLKSAGMARYIDRNIKGISIPPEIIR
DIQKAPDKIKECVRVAAQIIGRIKDMGMPGVLISTVGWEDKLPLILDEAKL
>A0A3M2EPJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus-Thermus bacterium|TrEMBL
MKISTLLKHNRPLFSFEFFPPKTPQGEASLFRTLHELKPLKPAFVSITYGAGGSERRKTT
EWAARIQGEVGLTAMAHLTCVGHTREELRAILQGYAEAGIQNVMALRGDPPKGAGGFQPT
EGGFRYASELVAFIREEFGDTFTLAGGAYPEGHPEAVSLEADLHHLKQKVDAGLDFLVTQ
LFFNNALYFGFLERARRIGIEVPILPGLMPITDLAQIRRFMDMCGASIPGPLLSRLERAQ
SPEEVLEIGVEHTTRQAQELLEAGVPGLHLYTLNKSPATRRVMENLQGVLR
>A0A0S8DK10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium SG8_40|TrEMBL
MGSESRSGLSFEFFPPQTPAGAENLRGVRQRLAQFSPEFFSVTFGAGGSTQERTRDTVFE
ISREGFAVAPHVSCIASMRDSIKGMLDEYRAHGIRRIVALRGDLPSGMAQAGEFRYASEL
VTFVRVEYGETFHIEVAAYPEYHPQSRSVRDDLLNFKAKVEAGADSAITQYFFNADAYFH
YRDECAKLGVTIPIVPGIMPIGRFHQLARFSDACGAEIPRWIRRKLEGYDDDTESIRDFG
LDVVTRLCERLLHNDAPGLHFYTMNQADTVCTICERLGLKSSPG
>A0A1Y3T4C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. An81|TrEMBL
MKLAEAMKEKMLLSFELFPPKTEKGMENLPGTIEHLCKYKPEYISCTYGAGGGNVGANRE
VCQMIKKAGPIPVTHFTVIRNTKEGIKEQLDQYLAEGVDHMLALRGDLPLGETTTCGDFD
YATDLVKFVKDQYGDKFEIAVAGSPEGHIACRSLEADISVLRQKQDNGADYIMTQLCWDM
EQFKRWLDAIRKAGVTMPVDVGIMPILDQAATINMALSRNGCVMDRELSRLISRHWLFPN
PFNPKDAEGKPFDMFYDKKVKEFKEEGIEYTIRQIDEYRALGVNGIHLYALNKWKDVSEI
IERSGLRTLV
>A0A0H2S5L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schizopora paradoxa|TrEMBL
MKLIDKINARTSSTPFYSFEFFPPRTDEGFANLLARISRLSEPDPLAVSVTWGAGGTTKE
RSLDLAQITQSEYGVDTILHLTCTNMELGSVDDALRKAKALGIQNILALRGDPPRGEEYW
IPTDPRFTHALDLVKYIKSSPEFASSFCVGVAAYPDGHADREVDAETELDHLKAKVDAGA
DFIITQLFYDVDAFIVWLGKVRAKGVNVPVIPGIMPLQSYTSFRRLTKLCGTQVPAQLDL
DLDAIRHDDQKVKDFGVSLAAKMISRLTTEADVKGVHFCTLNLERSVRKILETLQWSGES
SLPNNRLIVDASTMPSPDVPPSGKDLLINPVDASQSATNKLNSTQPIAETQEPGKGDVNN
ASTWDEFPNGWFGDYKSPAFGTQSDPWNPGTALSRAVAKSHKWGHPKCIEDLTHLFLAHL
HSKLASTPFSPAPLSPESLLILPHLEKLTSKGWWTVFSQPAVDGVSSRDEIFGWGPSGGY
VFQKGFVEFFAEKKDVDLIESRIRQKGEGWVQFFAANAKGDLRTNVPPGGKNAVTWGVFP
GREIAQSTIIERDSFFSWKEEAFLTWKQWAFSYPPESDERKLLESVHDNRWLVSIVHHDF
KDAPKLWTFVFDE
>A1U549|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8)|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTREEIGELLDVYKENGINRIVALRGDMPSGMGASGELRYAN
ELVEFIRQHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEQMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCQKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A0Q5P664|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Leaf177|TrEMBL
MKPIELSFEFFPPKTPEGIEKLRATGAQLKTLNPKFVSVTFGAGGSTQQGTLNTVLEMMK
QGLEAAPHLSCIGSSKESLRGILGAYREHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFNIEVAAYPEYHPQARSPKSDLDNFVRKVQAGANSAITQYFFNADAYFRFVD
EARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPKWIARRLESFGDDKESIRAFGLDV
VTGLCERLVKEGAPGLHFYTLNGAAASKTICERLKLLG
>A0A367F606|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces reniochalinae|TrEMBL
MRAAQDDPKAVRALGIAHATDMGRRLIEEDAPGLHFMTTHYPTVTTEICRNLGLHLWFVR
PDP
>A0A133L0S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weizmannia coagulans|TrEMBL
MPPFLGGFFHIIQRECKNLNLLETLKNRILVADGAMGTLLYAYGADTCYESFNLTHPEDI
HAIHRAYIEAGASVIQTNTYSANYIKLAQYGLEEKVKDINKAAVQIAKEAANRDTFILGT
VGGIRGQRKTEATLAEIKRTFREQIFHLLNEGVDALLLETYFDAEELYTVVDIAKKEADV
PVIAQFSLIEPGVLQNGTPVRDAFKELENRGADVTGLNCRLGPHHMIQAFEEIPIPKRAF
LSAYPNASLLDYEEGRFTFTNNADYFKTCAEKLVEQGVRLIGGCCGTTPAHIKAIADGVQ
GLLPVTEKTVRPPKIEIAAAPAQHEPPLHEIVKKRRSVIVELDTPKTLNTTRFFEGAKAL
HDAGIDALTMADNSLASPRISNTAIASILKEKHGIRPLVHITCRDRNLIGLQSHLMGLAA
LGIDQVLAITGDPTKIGDFPGATSVYDLSSMELIAMIKQFNDGISHSGKSLHRKTNFSVA
AAFNPNVRNLDKTVGRLERKIRHGADYFITQPVFSTEKIEQIHEATKHLDAPIYLGIMPL
TSYRNAVFLHNEVPGIKLTDEILAAMEKTNGDPAKAREESLAISRTLIDAALGYFNGIYL
ITPLERYELTVECTRYIHEKTAVRGAGIV
>A0A345C3N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salicibibacter kimchii|TrEMBL
MEFLEKLKKEILVGDGAIGTLLYDRGYSGSIEDANRRAEEMVVAAHREYVEAGANVIQSN
TYAANRLKLKNYGLEQQMARMNTQGMRLAKQAASGKEEVYVAGTIGGIRDGRASPFSNQD
IKKATESQAEALMAEEPDAILLETYYDLHELVQAVRIIKRLSPEIPVIGNVSLGDVGVLH
GGIPVNDALLRLLNEGTDVVGINCRMGPAQTIASLEEVSVPEGTYLSAYPNASLPGLQDG
RLVYQSNPDYFKSQAEEFRQQGVRLLGGCCGTTPEHIRSFKEKLQDRAPLVKARAKVSTV
REQASAEVGNTIRLEKEGPSIIVELDPPKSLTKMDKFLKGAQALHEAGADAVTLADNSLA
TSRIDNLAASTLIKQQAGAHPLLHIACRDRNLIGMQSHLLGLHALGIRDVLAVTGDPTKV
GDFPGASSVYDLTSFDLIRLIKSMNEGFSHSGRPLGVQTQFTVGAAFNPNVSSMDKAVKR
LEKKIVAGADFVMTQPIYDVETLRLLKEATAHLDIPIYVGIMPLINGRNAEFLHNEVPGI
QLTEQVRKRMADSRGDVQKGEEEGMAIAKELQEAGLDLFGRLYLITPFLRYHITAALMND
VKASASS
>A0A8D9VAU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEIASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A840QB37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora phatthalungensis|TrEMBL
MNAKVEQLQQYLMDARFEVLPLRDVVAQAELLPPGTTTTVTASPAKGTEATLDIAAQLLA
RGLHTVPHLAARMIADTAHLTALLDRMEALGLSEVFVVAGDSPEPRGKFPDALALLRAMD
ELGRRPARVGITGYPERHAFIPDATTIRAMTEKSRYADYVVSQICYDPHTVASWVKDVRA
RGLALPIYIGVPGVVDARRLLRISLKIGLGESMRFLRKQHGVVTKLFTRYTPEELFDELA
PYLVDPAFGIAGWHFFTFNEIAKTVQWRHEQVARLREVPA
>A0A1S2LT37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerobacillus alkalilacustris|TrEMBL
MGFLEEMKTRTLIGDGATGTFLYLKGLDRCFEELNISDPQKVRDVHNAYIEAGSEVIQTN
TYAANKIKLARYGLEDQTDLFNKSAVQLAKSAAADKNVYVLGTLGGIRGFQKRAQSLEEI
EESFKEQLDSLLNTEIDGLLLETYYDFEELTRCLTIARKATNLPIVSHVSLDEVGVLHGG
LPLGDALSALQDLGADVVGMNCRMGPFHMLQSYEDVPLLDKAYFSAYPNASLPDYIDGRL
VYQTNPQYFGESAKSFVREGVRLIGGCCGTTPDHIRAVSNAVKGKEPIKVKHVKAKQRKN
ITVFHKDNKESLQEITLRRKSVIVELDPPKKLNVDDFIEGSKKLKEAGVDAVTLADNSLA
SPRVCNLSLASIIKSQHDVRPLVHITCRDRNLIGLQSHLMGLHTLGIDQVLAVTGDPTKI
GDFPGATSVYDLASFDLIRLIKQMNKGVSFSGKDLGAQTNFAVGAAFNPNVKHLEQAVKR
MEKKLEYGADYFLSQPVYSKEQIKKIYEATKHIKAPIYIGIMPLTSSKNAEFLHNEVPGI
KLTDETRERMARLSNDKIASQNEGVQMAKELIDEVHRYFNGLYLITPFLRYEMTIELTNY
WTSLTNVLSPPKKVSY
>A0A7W8XDU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium lentis|TrEMBL
MALKNEAQARDIGISFEFFPPKSEEMEGQLWNTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRRAGISIPIIPGIMPIQNLTQLKRFAGACGAIIPGFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIRDFHLYTMNRSPLVSAVLDNLGLSRRAAKNAGAAA
>A0A7C6DMB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MRIDDILGKGKPTVSFEFFPPKTDAGFTSLFQTIDELRSIRPSYVSVTYGAGGSTREKTV
TLVERIQREIGIRSMAHLTCVGHTKDEIGRILDELWSAGIRNVLALRGDPPHGQAWFVPT
PGGFEYADQLVSFVASRHDFCIGVAGYPEGHPQCLNRTRDLENLKRKVDNGGRFVITQLF
FDNADFYRFRDAARWMGIKVPIIAGIMPIQNVNQIKRFVSMCGAKIPHPLLLKLESLEHD
AEAVAQAGIEYATRQCQDLLFHGVDGIHFYTLNKSKATVQICKALNVEHAV
>A0A6M1N550|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. SGG-5|TrEMBL
MKIIDHIKNAKGKPLFSFELLPPAKGQGIQSIFNTMDELMEFNPPFIDVTYHREDYLYKQ
HTSGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTPGGHAYATDLLQQVVDMNQGKYLHENIESSARTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVTKCREQDINVPIIPGLK
PLTTKKQLIALPKIFHLDIPEELSDAVSVCKNNAEVQQVSTEWMVHMCKELIDFGAPVLH
FYTMSNPGPTKKIVERLV
>A0A5T1DUG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDVCENLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALADIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLIKEELHA
>A0A373T246|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF25-13|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPD
AMKQAGIAYATDQIIDLLANGVNNIHIYSMNKPEIAVAIMNNLSEIIKC
>A0A5T1C6Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDVHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALADIDIPIYAGIMPITNKRQVLKISQLCRAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKKELHA
>A0A0G2EIE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeomoniella chlamydospora|TrEMBL
MDKITDKLAALPPDATYFSLEFFPPKTQAGFSNLQARLSRMAQALRPLFVTITWGAGGST
ASKSLELAEVCQRQLGLTTCLHLTCTNMNRKLVDEALREAKDLGIRNILALRGDPPRSEE
YNLDEEEDSNKDFTWAVDLVRYIRKNHGDYFCVGVAGYPEGHSDESHPEHQSVEHDLPFL
VEKTSAGANFIMTQLSYDIYAYSKYEQTLRSHPSGVFKTIPILPGLMPIQSYQVLKRVTK
LSHAKVPAKILERVEKVKTDDEAVKSVGVDILSELVTEIRNLPSPPSLPRGLHFYTLNLE
KSVAYILERCNLIPDPESPDYSAGSGSDSDTAVIVTHEDATIPSPSIDNSIGESGHGNHA
RRRASSVNAQPHNRLIVDHPVQTNKPIGRASRTSSQDHEASSLLAGVPATLPDRTTNLLI
SEGLGSLGREATWDDFPNGRWGPSNSPAFGEIDGYGPSLHVSPAQARKLWGFPTTHADIT
NIFKRHVLGELPCVPWSDDSDQGGGDGALREETFTIQKELLSLIEGQGWWTIASQPAVNG
IRSSDPIFGWGPQDEGYVFQKAFVEFFMPRDQWEKTLRPRLQELGNEEIAYLVTDDKGQF
ESSTTGAPASAPSRSASLSTSVTSSGTTGMVNAVTWGVFRGREILTPTIIEEVSFRAWGE
EAYGIWEEWRRVFPRGSSHEKFLQECKQSYVLVNCVGQKFGEGEGKRLWDVLLGKALKD
>A0A398C298|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Simplicispira hankyongi|TrEMBL
MSAANIPDASNAACPVSFEYFPPKTPEGAAKLRGVRQQLQALAPEFCSVTYGAGGSTQQG
TFDTVREILQEGVAAASHFSCIGATRQSVREQLAMLGAMGVRRLVALRGDLPSGYGLGGE
FHYASDLVAFIRAETGDAFHIEVAAYPEVHPQARSPEADLRAYVAKVQAGADSAITQYFY
NADAYFRFVDDATRQGARVPVVPGVMPIGSSSQLLRFSDACGAEVPRWIRLRLQSYGDDV
ASIKAFGLDVVTRLCEQLRAGGAPALHFYTMNQSQAVLELCRRLGRTAPVSAA
>A0A1S2U6L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIIHLPCIHSSKEKITHILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAIKHLLNEELRA
>A0A1R0LFR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. IMTB 2501|TrEMBL
MNPAVTVPPAVGAALLDDFSLEMTGKDVPRLEEARGSIPRGTRINITFLAGEDLGMRLAA
ARAVKRLGFVPVPHISARRLPSRAALEEFLSGLAADGTAENVFVVGGDPARPEGPYDDAL
AVLRTGLLQRHGVRHIGISGYPEGHPAIADGTLWSALTDKAAAIGAHRFDGDVITQFGFD
ADPVLSWLEAARARGVHLPVRIGVPGPAGVRRLLGYATRFGVATSASVARKYGFSLTNLM
GTTGPDRFLHAFAQRYDPERHGAVKVHFYTFGGLRHTAEWITGFRRTAPSTRTP
>A0A7G6UHQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nasuia deltocephalinicola|TrEMBL
MIKFSIEFYINIYKIKEILNFNISMVCLKPFFLTITYNKFNINKKVINYLIKNGLKVSPH
IICKKKIRNFNYLLNSYFLINLKNLMIIKGDNSKNNYYYSYNILNLIKKNYINKFNVFLG
DYAESHPNSLNFLSNIKNNKIKNIVKKNINFISQYFYNIESYYNFYDSLKKINYKIKLIP
GIMFINDFYKIISFSNICKTELPLWIIKKINNNKFYKKEYKKINKEIILNLILKLLNFKV
KILHFYSMNNLYLVNIICESLNNNLNL
>A0A6L9ZP44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO3B5|TrEMBL
MNRFRNAVKSGEFLVTAEVAPPKGADPTHMIEMASTLKGRVHAVNVTDGSRAVLRMSSLA
ASIILKNNGIEPICQVACRDRNRIGLQADLMGASALGLNNILALTGDPVKAGDHKDARSV
FDMESTRLLKMIAKLNQGMDWNEKALPDGATDLFVGAAVDPQSPSWSGLKKRFELKLLAG
CQFFQSQLISDFDKLEKFMNQIAVDSNKPILAGIFLLKSAKNAAFINKYVPGVDIPEHII
NRLAKAEKPLEEGIKIAAEQVQIASKICHGVHLMAIKREDLIPRILDMAEISPI
>A0A8I1IXI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MLITETFKDNGLSTSFEVFPPKNNAPYKPVEDAVDKLAVYHPDFISVTYGAGGGTSVNTP
KIAAHIQNDLSIPALAHLTCASSTKKELDKIINDLGAAGVNNILALRGDLPDGYDPDNPD
YYHYAYELIETIKSKGDFCIGAACYPECHPEAESLQKDIENLKIKVDSGVDFLVTQMFFD
NNVMYSFLYRALKAGIDVPVIAGVMPVINAKQIKRSCALSQTSLPPRFRRMMDRFIDDPE
ALKQAGIAYATEQIIDLISNGVSGIHIYTMNKPEVAGKIMENLSSVLSAR
>A0A0P4RIA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lydicamycinicus|TrEMBL
MRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALRGDPPGDPMGEWVRHP
DGVGYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVAKCRAGADFAITQMFF
YPEDYFRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATDLCARLMAEEVPGLHFITLNHSTATLEIYENLGLHQQS
>A0A7G5J791|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNRDFTFAVDLVRYIRQKHGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYL
VEKTQAGADFIMTQLTYDIEAYTRFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVQIPPQILAKLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLRGFHFYTLNLEKT
VSFILERCDLIPPYSEDFDAIEEGGDISAMDGAHLRSLTRRRASSINSLPHNRVIVDKLH
ASEVSSKASVSHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSS
GLNAETEVIRPELLQLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFF
CPSKDYHSILKPLLQKHGHEKLAWFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWG
VFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNDIKDDVWLVCVVG
QDFGAGTEMGSEEEEDEKKFMWRVLLNAKK
>A0A3D2QT37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MNIREYLKKSKLIADGSFGTYYSKKYKTVDIPEYANITASQRISEIHTEYINSGAKLIRT
NTFASNTYSLDCSIEQVKENIKAAYKIAKEAVEQSGKEIFIAGNIGPVPAVFQPDFEAVE
EEYYQIAKTFIDEGADILCFETFTQSEHIMPAIKRIKEECNPFIIVQFCVNQYGYSEAGE
SAERLVSETAFSKCVDAVGLNCGVGPAHMQQILSRINLNNNCFVTAMPNAGYPLLVRNRV
KYADNPIYFASKVNGMALLGADIIGGCCGTTPDYIREVAKTVDLTPTVKSDETSANNENE
KPVIKKSFFRNADGTIKDKKLIAVELAPPFGADDKKLLEAAHMLKGLGVDVLTFPDSPSG
RTRIDSVLMAQKVKNVTGFEVMPHVCCRDKNAIAVRSTFLGASINDINNFLIITGDPIPV
MARQVVKSVFNFDSVGLMRIADEMNSEALKDSPLTYGGAINQSRRRIESEIKRVQKKMEA
GAEFFLTQPVFTAEDAERLRRVKEETGARILCGIMPLVSRKNALFMKNEISGVNVTDEVI
ERYPENADREDGENVGVELAKEMIAATRDFADGYYFSFPFNRTYLLKRIIQEV
>A0A160SYL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola subsp. Tuberolachnus salignus|TrEMBL
MMFQNSHHIISSLFNTNILKNKLFFSFEFFPPKNLKEIQILLKIIKKLEFLNPLFFSLTH
SAKETNYCYTEKILSILLKNTHIPVFPHLTGINFQKSEIIQIAQKYSQYDIKKIVVLRGD
ILKYSQNSQLYATDLIKILKNVNNFQFIVAAYPEIHPESKNMSEDLKNLKNKEKLGASSA
ITQFFFSVEKFLLFCKKCKKSNIKLKIIPGILPILSFKQLIHFTQLTNVHIPEKMLYFFS
KYKNCPKKFEEYSIQVATNLIFELLQKNILHFHIYTLNRIYLFSKILNKLEKMLL
>A0A2J6XEE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobium narugense|TrEMBL
MNELRIKERYKSERTGFSLEFFPPKERDQEEKFKETIKKYIELNPLYVSITYGAGGTTQD
KTFEIVKFVNSFKAFAVLPHLTCIGATKDSVNFLIKKYDNLGVCNILALRGDPPKNVENF
DISKGEFKHAIDLIKYVREYFNHFSIGVAFYPEGHAQASSFEEDFEHCIEKMRLADFAIS
QMFFENSYFLRYRDLVAKRGVDITLVPGIIPIGNFEKIKEFSKFCKVEIPKKLEDIMSKA
SSQLDMKKAGIDYATQQCAELIKEGVKFFHFYTLNQFDLCSKVIENFW
>A0A428WTY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC 00631|TrEMBL
MRPLGEILAAGERTYSFEFFPPRTETGERTLWHAVRRVEALAPTFVSVTYGAGGSSRDRT
VRMTERIAAETTLRPVAHLTAVGHSAAELRRIIGQYASAGVRDVLALRGDPPGDPRGPWT
PHPRGFRHAGELVRLVRELGDFGVGVAAFPERHPRSPDWESDIRHFVAKCRAGADYAITQ
MFFHVEDYLRLRDRLAAAGCTTPVIPAIMPATDVRQITRFAELSGAAFPPDLARRLEAAR
DDAAESRRIGVEHATEMALRLLAEEAPGLHYITLNRSTATLEIHRNLGLPRGGPRTAPAA
A
>A0A4V4JP00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEVTAPEAPQ
KVNGATNSEKHEEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A355G364|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
YGAGGGTSEHTVDLAHEAKTDGVTALAHLTCYSSTKEKVLDVIRQLKEKGIENILALRGD
RASDSPIGEFNHASELMELIATQGDFCVGGACYPECHPESASIIDDLDGLKRKVDSGCRF
LTTQMFFDNSVFYKFSNQLRSYGIQVPLVAGIMPVTQSSQIERIVKLSGCGIPLELSSIC
ERFADDPAAMKQAGIAFATNQIIDLIASGVNNIHIYTMNKPDIAKAIMDNLSDIIGKQGT
QYEA
>A0A4R9Q5S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1D.F.Ca.ET.231.01.1.1|TrEMBL
MSARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPEAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRRPWKREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A1M3QF26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. 60-20|TrEMBL
MSSRSESRDDGIRISFEFFPPKSEEAEQQLWNTVEELSDWEPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLAAGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVGALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKAENGADRALTQF
FFDNDAFERYHDSVRAAGIEIPVVPGIMPIQNLTQLKRFAGACGTNIPSWLDERFAGLDE
NTEERARVAAEVAAEQIQDLMRRGIHEFHLYTMNRSALVSAVLERLGLQRKVDARAGAAA
>A0A354NE42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
RCYPEIHPEAANMVDDIRNLKKKVDAGASHLISQLFFDNSSFLNFLEKARIAGINVPIEA
GIMPCVNAKSIQRMVTMCGASLPLKFTKMINRYGDNPEAMRDAGIAYAVDQIIDLVAQGV
DGIHLYTMNNPYIARKISESVEKVIRCDK
>A0A5M9ZL01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium myosotis|TrEMBL
MHTPMFSLEVFPPKRNAPVGTIYDTLDGLEGLEPDFISVTYGHGTHTDRTATARIANTIR
NEYGIPAVAHLTALYSDRDKVDEALDMFEQAGVQAVLALRGDYIEGEEPVGVFEHASDLA
AYIRERKPDLKVFGACYPEGHYQSSSLDEDIANLKTKVDAGVTHLISQLFYDNDDFYRFL
DKARAAGIDVPIEAGIMPVRGAKSVRRMAERNASRIPDHLAVMLDRWEGNADAMRAAGIA
YASEQITDLVAHGVDGIHLYSMNHPATTRRIWRNVEPLFAA
>A0A4S9ZU02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MTKLAVTRAIMHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRM
AHSLRPLFVNVTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAK
ALGIRNILALRGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVA
AYPEGHSDQSHPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGA
FKTIPIIPGLMPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMV
ETLKKNSYSGPKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAK
ARRRSSLANSAPQNRVVVDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEG
ALGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFAR
HVRGELDAIPWSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPN
GFVFQKPFVEFFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTG
KEIVTPTMIEAVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFT
ENNGLWKMLLEA
>A0A3D1VHL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKIKAILEQKPTVSFEVFPPKQWDKIEGTKAVVKEMVKSHPAFMSVTYGAAGTTSGFTTE
IAREILDDGVTPLAHLTCLTSTRDKIHQVVAELQENCIENILALRGDIPRDFQFPAEQYF
EHAYQLVNEIRTLGDFCIGGACYPEVHPESKNRVEDLEHLKQKVDCGVDFLTTQMFFDNT
VFYNFREMCAIKGIDVPLIAGIMPITKASQLERTVKLSGCSLPTKFVKIVERFGDRDDAM
QQAGIVYAAEQIIDLMANGVDHIHIYTMNKPDVAGAIVRELGSIIHE
>A0A348P3D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MLITDYLKDGKVCTSFEVFPPKNDMPFEPVKAAVKELSALSPKYISVTYGAGGGTSQNTA
EIVSYIQDELNVPSVAHLTCASSTKAEIDAILANLKPKGIRNILALRGDLPADYNPDDSN
YYKYASELIERIKQDSFFSVGAACYPECHVEAKNSVEDLQHLKHKVDCGAEYLVTQMFFD
NSALYSFLYRALKIGIDIPVTAGIMPVMNSKQIKRSCALSGATLPSKFRIMLDRFSDDPV
SLQQAGIAYATEQIIDLISNGITNIHIYTMNKPEVAQKIMANLSAIL
>A0A419J4W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MSFREILESGKFAVTAEIGPPKGTDIKEMYHHIEVLKGKIDVANVTDNQSAVMRISSLAV
SKIVLDNGMEPVLQMTCRDRNRIGLQADLLGASVLGIHNVLCLTGDHVNAGDHKQAKSVY
DVESVQLLKIVEGMNNGKDMSGNEMKGATNFYAGAVVTPEAVPLEPQLVKFEKKVKAGAK
FFQTQAIYDMEKFKSFMQYAKKFPVKMLAGIVVLKSAGMANFMNKNVPGITVPQELIEEL
KAAGKEKALETGINIAARHIKQLKDEKICDGVHIMAIGMEDKVPMIMERAGLL
>A0A4S9KBM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEITAPEAPQ
KVNGTTNGEKHEEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A1I3UDX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. UNC496MF|TrEMBL
MLRDKIARKAPGIVTYGMTPPKESHEPDKIAEIARKQAERLKGLGIDGLILYDVQEESDR
IEADRPFPYLKTIDPTAYSETYLSGVDVPKIIYRCVGQDSEAQLARWLQADPDEDRFAVF
VGASSSRQEVTLRLPDAYDMSRTLNPNLTFGGVVIPERHLKKNDEHLRIASKVRSGCGFF
VSQATYNVEATKNFLSDYYYYCQEQELEMAPILINLAPCGSAKTLAFMKWLGISIPKWLE
NELNHSHDVLDKSVTLLHGIFEEIFDFGLEKGMPLGCSVESVSTRKVEIDASIQLVRDIQ
AMIRAKMPSALAR
>A0A117MM47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes awajinensis subsp. mycoplanecinus|TrEMBL
MSLGLPSKLPGTPAIGELIRGAAPTFSFEFFPPKTPDGERLLWQAIRELESLRPSFVSIT
YGAGGTTRETTVAVTERVATETTLLAMAHLTAVDHSVAELRNVIGRLAGAGIRNVLALRG
DPPGDPMGEWVRHPEGVRYAEDLVRLIRESGDFSVGVAAFPYKHPRSADVESDTLNLIRK
CRAGADYAITQMFFDAEDYLRLRDRVAAAGCDTPIVAGVMPVTRMATIARSSQLSGAPFP
PELLRRFDRVAGDESAVRELGVEVCSEMCARLLDEGVPGIHFITMNRSTATREVWQRLAP
SDVAAAA
>A0A4Y6IXF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella marisflavi|TrEMBL
MAFHHAQHANSLNQSLSELNGDINVSFEFFPPATPEMETILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETDLVAAPHLTLVDASDEELVELAKHYWNSGIRDIVALRGD
LPAGSPKPTRFANDLVRLLKSVADFDISVAAYPEVHPDAPNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSIPRWLHKQFE
GLDDDPSTRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A7Y2UM86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp|TrEMBL
MFDFPYIIELLTPKKTDDQYPERLLNRFGERFNRAIESGCAVSIPDNPMGNLRMGALETI
EMLNLTFDPERLVINLNTFHLKDELDEILEGALQTGIRSLLVIRGDGGPDLSRLEPAHIG
GKFNVASSTDLIDYINRAYPGKFMTGAAFNHYNPIEVELKRLDKKIGAGAQFIVTQPVIG
NDSRLNQLTARDIPLVVEAWMSNNIELFSQSVGDDTLSIADYDPIDNLNLLHDSFPDSCI
YLSMLNFNEKFEELLPAL
>A0A7V3YH73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Caldatribacterium californiense|TrEMBL
MSVLQELLEQGVFVVTAEVGPPKGVDRESIVKKCAQIRGFVDAVNITDNQTAIVRLSSFA
SCLIVREAGLEPVMQLTCRDRNRIALQSDFLGACALGIENFLCLTGDHQSLGNHPEARSV
FDIDSVQLLGIFRKIRDEGVFANGEKVKGEVRAFLGAGENPFADPLEFRVFRLAKKVEAG
AQFIQTQAVFDLELFSRWMEEIRRLKLHEKVHILAGIIPLKSLQALRYMKNEVPGMVIPA
WVEERMQNARDPKEEGVRIAVETIAALRAIEGVRGVHIMAVAWESIVPEIVRASGLFPRP
GQGGGEGV
>A0A7W2U385|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colwellia sp. 6M3|TrEMBL
MKNGSELRARYNDVNRGVYFIGTTPPKSDTPIDQVSTIADKLLERVSDIDFDGLIVYDIQ
NEDSRTSKPRPFPFKSTHDPRLYSSLLQQKSNRPVITYKSVVQSNGDDFNQWANEAWHEY
GIRDIVLVGSPSQQNNISLPLGKAYETLVANENDFFIGGITIAERHANKGNEHAKLIEKH
QQGCNFFISQAIYNPQATIDMLTRYAIECQQQGIKPQRIILTFSPCGSMKTLEFIEWLGV
SVPEATSLRILNAERPLYESIRICSNTLVQILDAVLPYKVPLGLNIESLTNRKEEIDGSI
LLYKLLRSTMDNYLAKKELSGLFTN
>A0A838C312|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia gladioli|TrEMBL
MKPIELSLEFFPPKTAEGADKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLSAAPHLSCIGSSKDNLRAILDQYRSHGIRQIVALRGDLPSGMGEVGELRYACDLVRF
IRAEHGDWFHLEVAAYPEYHPQSRSPKQDLQHFAEKVKAGANSAITQYFFNADAYFRFVD
DAARLGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGADV
ITAMCDRLIKQGVPGLHFYTLNLATPTRVVCERLGLSS
>A0A8J6CSV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium anomalum|TrEMBL
MKVIEKIQSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIICVETMMHLTCTNMPIEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNYGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEELSKPMEFTLEQKCANLGLIEESKISRSLPWRRLQMFFVLKKMFV
QYFANDGRSNRPKSYITRTIGWDQYPYGRWGDSRNPSYGALTDHQFMRPRARDKKLQEEW
ATPLNSIDDIQEKFKSYCLGKLRSSPWSELDSLQPETKIIHEQLGKINLKGFLTINSQPA
VNGERSDSPSVEPMVSQLTVFVVKAGAVFALNLFKLGCLQEKLDALVNKCKPLSSITYIA
VNKKGNLISNIGTTDVNAVTWGVFPAKEIVQPTVVDPASFMVWKDEAFEIWSKAWAALYP
EGDPSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>A0A223EN40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peribacillus simplex NBRC 15720 = DSM 1321|TrEMBL
MNFRKEVKERMLVGEGAMGTLLYSNGIDQCYEELNCTNPDQIESIHRAYLEAGADILQSN
TYGANFNKLKRHGLEDEVSRINRQGVILAKKAAKGKAYVFGTIGAQRSIRKSDLSLEEIK
RGFREQLYSLLMENPDGILLETFYDLEELETVLQIVKNETGLPIIANVSMHELGNLQNGI
HLNEAFQKLEQLGADVVGVNCRLGPHHMIRALEEVSLPKQASIAIYPNASLPDYVDGRLV
YKAVPEYFGSSALELREQGATIIGGCCGTTPLHIQAVKNAIGSLAPVKEKFTKSREIEII
EVNDRELELPLYEKAKTERTILVELDPPKKLGIESFMTGAEVLKKAGVDSITLADNSLAS
PRISNDALANLLKNQLNIKPMVHITCRDRNLIGLQSHLMGLQTVGLNEILIITGDPSKIG
DFPGATSVYDLSSFDLISMVKQFNEGLSYSGQSLGQRANFKIAAAFNPNVKYLDKAVLRM
EKKIACGAQSFLTQPIYSVEQIEEVYEATKHLDTPIFIGIMPLTSTRNAEFIHNEIPGIK
LPDNVRRAMALAGDDPVKSRIEGVNIARELVDAAREKFKGIYLITPFLRYEMTAELTKYI
RKVDSKHTSEVAVHE
>A0A833VB34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia gladioli|TrEMBL
MKPIELSLEFFPPKTAEGADKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLSAAPHLSCIGSSKDNLRAILDQYRSHGIRQIVALRGDLPSGMGEVGELRYACDLVRF
IRAEHGDWFHLEVAAYPEYHPQSRSPKQDLQHFADKVKAGANSAITQYFFNADAYFRFVD
DAARLGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGADV
ITAMCDRLIKQGVPGLHFYTLNLATPTRVVCERLGLSS
>A0A4R6MP79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 245|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAIDLVRQINDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A1F5RI35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Edwardsbacteria bacterium GWF2_54_11|TrEMBL
MHVTQHLEQRKKTLVSLEITPPEKGHSIQVIYDAIDRLMPFNPSFINVTYHQQRIVYEEV
NGVIVKIPKRKKPGTVGICTALANRYRVETVPHLICGGFNRYETEDALIDLQYLGFENLF
VIRGDPPPDYKGFLPEPEGHHHACQLVEQIAHLNRGQYLENLDDAIPTNFCMGVAGYPEK
HYEAPNLADDIRNLKSKVDQGASYILTQMVFSAELFESFVKKAREAGITVPIIPGIKVMV
NRDQLTSIPRDFYVSLPEKLVDTIKQHDDKAAARQAGIDFTARLCQDLIDLDVPCLHFYT
LGKTSATAEVMKQLKEKQLI
>A0A1H8ZWI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces radiopugnans|TrEMBL
MALGTPSTRTDRARTVRELLASGERSYSFEFYAPKTEKGERTLWNAIRRVEAVAPTFVSV
TYGAGGSSREGTVRATERIATETTLTPVAHLTAVDHSVAELRNVIGQYADAGIRNMFAVR
GDPPGDPTGEWVPHPQGITYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDSDIRHFVA
KCRAGADYAITQMFFYADDYLRLRDRVAAAGCDVPIIPEIMPVTSVRQIERFAKLSNAAF
PPDLAERILAVEHDPAAVRSLGIEYATELCARLMSEDVPGLHFITLNHSTATLEIYENLG
LHRRG
>B5RF62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella gallinarum (strain 287/91 / NCTC 13346)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0R1L7Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus sunkii DSM 19904|TrEMBL
MSLTELFKTKTVFSLEVFPPKKSSPTEAILPTLKRLQSIHPDFISVTLGAGGTDHCNGTV
EIANLIQNQLDIPAVSHVPGLYQSKEDVLALLDRLDSINVKNILALRGDRIPGKEPVGDF
NHANELVAFVHEQRPDFSIASACYPNCHTEAPDFVNDITHLKQKVDAGADHLISQLFFDN
QAFYDFKEKTELAGIHVPIEAGIMPCTNKNQIERITQISGVPIPKKFAAIMDRYQNSEEA
MLDAGIAFAVDQIIDLVSQGVDGIHLYTMNKSKIAKRIWNETRSVFEAADTSIQKDHA
>A0A4R1CVZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. BMG5.11|TrEMBL
MTAAGSTTRMSTPTVAECLASGRTSFSFEFFPPRTAEGERHLWTALREIEALHPTFVSVT
YGAGGSTRDGTIRVTERIATETTLTPIGHLTAVNHSVGELRQVIGGYAGAGVRNVLALRG
DPPGDPQAEWVRHPDGLGHADELVRLVRSLGDFCVGVAAFPDKHPRSPDLETDARFLVRK
LDAGADFAITQFFFGADDYFRLVERVRRLGCDAPIIPGVMPVTNLAQIERMAQLSGADFP
ADLAARLHEVADDPAAVRAIGVEVATELSERLLAGGAPGLHFITLNRSSATREIYQSLGR
>H5X0Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora marina XMU15|TrEMBL
MSTVTSVIERLRGRTAGFSVEFFPPRDRADEAVLWRSIRELEPLDPAYVSITYGAGGSSR
QGTIRSIARVATETTLVPMAHLTAVNHSVAELRHVIGSYAAVGVRNILALRGDPPGDPYG
EWVPHPHGLRYAEELVTLVCSLGDFCVGVSAFPYGHPRSPDLATDTAHLVRKFAAGADFA
IAQLFFEAADFLRLRDRVYAAGCDKPIIPGIMPLTTPRTLAKTVELSAAEPPRWLVDRLL
PLSDDPKSFRAAGLDITTQLCEQLLAEGVPALHFYTFNRAKATRELVGRLGLVRTRA
>A0A0N0EWH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. myricae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A024H285|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter siccitolerans|TrEMBL
MALSYELFPPRSPAAAETLWTTIRELETTEPDYVSVTYGASGSNRDTAVELINRLLLETT
LRPLAHLTCVGNTPQELAGIIGELLDTGVRGILALRGDLPKDGGEPVPGALRYAQDLIEL
IRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEEHDVEVLLAKQRSGADFAITQVFFHA
GQYADLLTRARRAGVTIPIIPGVMPLTSLRRLKRLGELAGVEPAAELMERLAAADNDIER
LHIGVDATVDLANAALDAGAPGIHLYTFNEHQSALEVLDKLALPRHSRSGIRRAALAGRQ
LAS
>A0A0H4I5S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter psychrophilus|TrEMBL
MESQKQFKRRFSFEFFPPKTEQGKVKLQGVRDELAAVNPDFFSVTFGAGGSTRDRTLETV
FSLHQQGISAAPHLSCVGGTRAEIKELLDTYKENGINRIVALRGDLPSGMGAAGELRYAS
ELVSFIREHSGDYFNLEVGAYPEFHPQARSAEEDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKAGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWVRKQLEAYGDDSESIRQ
FGEEVVTRMCEKLLQAGAPGLHFYTMNQVEPSLGIWKNLGLGEREKIPF
>J8ILJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VD048|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKRLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A502MMN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B4-1-3|TrEMBL
MTALQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAQRLDHILHDEITETQVDMVK
TAH
>N6Y6N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera linaloolentis (strain DSM 12138 / CCUG 41526 / CIP 105981 / IAM 15112 / NBRC 102519 / 47Lol)|TrEMBL
MNSTEISIEFFPPTTAEGAEKLRATRDKLAALKPAFFSVTYGAGGSTRERTFATVKEIAA
AGFEAAPHLSCVGSTRDNIREILQEYIGAGIRRVVALRGDLPSGVVDPGEFRYANELVAF
IRAETGDRFQIEVAAYPEWHPQARSPQDDLLAFKRKAEAGANSAITQYFYNLDAYLYFVD
TVRGMGIDIPIVPGIMPIGSFSKLARFSDACGAELPRWMRKTFESYGDDTDSIRAFGLDV
VTHLCEKLIAAGAPGLHFYSMNMAGPTTEICKRLGLAR
>A0A1E7Z915|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas confluentis|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPNSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVQAAPHLTCVDASRDELKQIAQEYWDSGIRRIVALRGDLP
KGVDKTEMYASDLVSLLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTSVYLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMYDGL
DDDDQITRNLIGANIAMEQVKVLAKEGVKHFHFYTLNRCELSYAICHMLGVRAD
>A0A1Q3W8C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma sp. 48-14|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICAAIMHKFGVDPVPHVLCGGFTREETEDFLIDLHYLGID
NALVLRGDPAKPFTTFKPKENGYSYASELVEQVANMNRGIYLHEEDTALAPSDFCIGVAA
YPEKHFEALDHDIDFHYLKQKIDKGADYIVTQMFFDNKKFLDFVARCRQEGISVPIIPGL
KPLSTRKQLQILPKLFHLEIPEDLRKAVEACENDQQARQVGVEWCIQQCRELTAAGAPVL
HFYTMGKADNIMKIARELF
>A0A1F9CLU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_65_10|TrEMBL
MRIAEFLQEAAPAGRKCLSFEFFPPKTEAGEAALYVAIEELRPLRPTFVSVTYGAGGSTR
NKTVEIVSRIKRDLGIEAMAHLTCVGASRSELRAVLQRLEGAGIENVLALRGDPPLGQAR
FERAPDGLGYANELAAFIRANFPFCLGGACYPERHPECPDGAAGLQHLGLKIDAGVEFLI
TQLFFENRFYFDFVAKVRAFGIPVPIIPGIMPVTNVDQIERFTAMCGATIPRGYRAALQS
RRDDPEAVIEMGVSYATAQCRQLLEEGVPGIHFYTLNKSPATRQILKALRASGHV
>A0A4Y3WI32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia hydrocarbonoxydans|TrEMBL
MKITDRIGGDRPVFSVEFMPPKDDAGEAELWKAIRRLEPLDPAFASVTYGAGGSSRDRTV
RTTGRIASETTLVAMAHLTAVSHSVAELRHVIAEYAAAGIRNILAVRGDPPGDPLGEWVA
HPEGLTYADELVTLTRSLGDFCVGVAAFPYGHPRSPDEDSDLQRLIAKVRAGADFAITQL
FLEPEGFLRLRDRLSAAGCEVPMLPGIMPLTTLRTLHRGPELSGAPLPPGLAERLERYAD
DPVAFRAAGMDLTVALCERLLAEGVGGLHFYTFNRSTATSELVHRLGLQARRGASVA
>A0A6B3GKH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID7982|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRL
>A0A7C7SWG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MSLANIYQRRFGLSFELFPPKTEKGEQALLRHVDHLNRFHPDYLTCTYGAGGSTQAKTLG
IITKVKERLDIPVASHLTCVGSSVDQLRSYLTEARQRGIDHIIALRGDPPKGESEFKATA
DGFRHANELVELIRSEFSNFGIAVAGYPEKHQEATSFEVDIENLKRKVDAGGQIVITQLF
YQNDDFYRFRDACDKAGINLPLVPGILPVTSLTQIQRISSMCGAALPASLVDQLGERDDD
VWQFQVGVEFAVEQVKDLIAHDVCGMHFYVLNKSAATSEVLQHAELDR
>A0A7W8HVM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium rosettiformans|TrEMBL
MTKTERPITRTSELKISFEFFPPKSPDMEAQLWQTVEALQPYQPDFVSVTYGAGGTTREP
TLSTVKRLIDDTPLATASHLTCVGATRDEVRAVVEEFEAAGVRHFVALRGDPQGGVGTRY
APHPGGYVNAADLVSGLRAMGDFEISVSAYPERHPESENDTVDLDMLKQKVDAGATRALT
QFFFDNDVYERYMERVQAAGINIPIVPGIMPIQNLTQLKRFASMCGASIPSFLDARFEGS
EGDAQARAAIAADLAAEQIADLSRRGVQEFHIYTMNRAPLTIATLDRLGVSPKAGRVSGA
AA
>A0A257PFH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium 20-64-7|TrEMBL
MTHSPQRGALERWTAGTRIAPLPAPEDAKAPAISFEFFPPKTPALESQLWSCVERLATLK
PEFVSVTYGAGGSTQARTHATVLRMVQETSLTPAAHLTCVGATREAVDEVARRYWEAGVK
HIVALRGDAPAGEAYAPHPGGYAFAADLVAGLKKIADFEISVAAYPETHPQARSAEDDLD
NLKRKLDAGATRAITQVFFDNATFLRFLDRALAAGITAPIVPGIMPVTNFTQAAKFCAQC
GTSVPAWMASLFEGLDDDPETRRMVAAATTAEQVRILQANGVDEFHFYTLNRPDLVYAIA
RILGVKPVGNAVGPD
>A0A2S6RPS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha6_Bin5|TrEMBL
MKKDLKISFEFFPPKNLKMHRSLWNTLNKLKIFYPDFVSITYGAGGSTRKRTHETIKKFT
YRPSIKPIPHLTCIGDTRNSIKKLAINYWEMGIKSIVVIRGDPENIKLSKKRKFVTFPNG
YNYSSELIKDLKKIRDFEIIVAAFPEKHPESINVDEDIDNLKRKIDLGASKAITQFFFDN
KKFYEFINLIEKKNIKIPIIPGILPIINFDKLNKLAESCNAYIPKKITNLYTGKKEFEFD
LSVDVATRQCIDLINNGFKNLHFYTLNRAELTGKICSNLTKKGLANKPYDAFWS
>I4IA54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis sp. T1-4|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFDCLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A3P1YVR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella forsythia|TrEMBL
MKTVIDLIRNSQRTAFSFEILPPLKGNSIQSVYQVIDKLREFEPKYINITSHHSEVIQRE
EPDGSIRTVNLRKRPGSVAIASAIQNKYGITAVPHLVCKGFTKDETEYGLIDLNFLGVNN
LLLLRGDVKRLDLTKDPELYHDHATDLQRQVNDFNRGIALDGSRIEDIETPFSYGMACYP
EMHEEALSMEADIQYAKMKVENGAEYLVTQMFFDNDRYDAFVARMRAEGVTVPIIPGIKP
IVFKDQLTVIPKIFHCIFPEPLTQALRQCKNDDEAKAVGIEWCIAQCRDLMVRGVPSIHF
YSFMASDSVRQVARAVY
>A0A2E6K5E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altererythrobacter sp|TrEMBL
MSPTLDQMREAQRALETPLFSGLPGDIEVSFEFFPPKTEKMSETLWESVKTLEPLNPRFV
SVTYGAGGSTRERTHEAVRRIVGETNIPAAAHLTCVQATREEVDEVAREYWAEGVRHIVA
LRGDAPDGADGYSPHPGGYENAADLIAGLKRIADFEISVAAYPEVHPDSLDRQSDLDNLK
RKFDAGATRAITQFFFEPECFFDFRDKAATAGIAGEIVPGIMPVLSFAAVQRMSGLCGTA
IPEWMEGLFRGLDERPEARQLVSATIAAELCRRLYAGGVRKFHFYTLNRAELSYAICHML
GLRPQGDKL
>A0A546ZLL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium rhizogenes|TrEMBL
MSSKNENGQGGIRISFEFFPPKSEEAEAQLWNTVEELSEWEPEFVSVTYGAGGTTKAPTL
SAVRRMIHETPFTTASHLTCVGATREDTHRVIDDFLATGVRRFVALRGDPPTGVGSAYQP
HPDGYANAAELVAALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRAAGITIPVVPGIMPIQNLTQLKRFAGACGTSIPSWLDDRFDGLDD
NADERAKVAADVAAEQIKDLVRRGIHEFHLYTMNRSPLVSAVLERLGLQRKADARAVA
>A0A353ZIE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MTRQNPLSAAYRPGQFDISFEIFPPKTAEGDGALWNSVAPLAAFRPTFISCTYGAGGSTR
GRTLELCEQITRRFDVPATAHFTCLGGTVDELREWLTWAGQHGVRNIMALRGDAPAGQAD
WKQVEGGLSYANELVALIRGEFPQFGIGVAGYPEKHPQAPSLEVDITNLKRKVDAGADAI
FTQLFYVNDAFYRFRDRCERAGIRIPIVPGLMPILNFAQIQRITSLCGAELPADLSRRLS
EVQDDKDAQFEIGVDFAAEQSLDLRKHGAPGIHFYVLNRSTACERILGALGLSPLVGV
>A0A173LWQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantimicrobium minutum|TrEMBL
MSNASPSSSLELNIGVPFSFEVYPPRNPELRDALHETILELAASGPDFISVTYGAGGSSR
DATLDCVKFILENTDVEPMAHLTCVAESYQGANELVRTFLDAGVRSFLALRGDPPQGTQE
GEDFLGDLGSAAELTQLIHRVQAEREPFVFVEEPRWHAGATRLSQKREFVRIGVAAFPNG
HPQSRSKTQDIDVLLAKEAAGANLAITQLFFHADDYLSFAQKAKEAGLSMPIIPGIMPVI
SPGRLRRMIEISGEDMPSDLEIALEIEPTVEGQREIGVEHAANLARELMAGGAPGIHLYA
FNQSGPVLDVLRRLEA
>A0A3P1XK39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella forsythia|TrEMBL
MKTVIDLIRNSQRTAFSFEILPPLKGNSIQSVYQVIDKLREFEPKYINITSHHSEVIQRE
EPDGSIRTVNLRKRPGSVAIASAIQNKYGITAVPHLVCKGFTKDETEYGLIDLNFLGVNN
LLLLRGDVKRLDLTKDPELYHDHATDLQRQVNDFNRGIALDGSRIEDIETPFSYGMACYP
EMHEEALSMEADIRYAKMKVENGAEYLVTQMFFDNDRYDAFVARMRAEGVTVPIIPGIKP
IVFKDQLTVIPKIFHCIFPEPLTQALRQCKNDDEAKAVGVEWCIAQCRDLMARGVPSIHF
YSFMASDSVRQVARAVY
>A0A3N5VI13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MKPNSKLASAIQSTAFIVTAEILPPPAAEEAAIRAAADVMGDSLAAVSVADNHSGIGTSS
LAVSSVLLGLGREPIYQVVTRDRNRIAIQSDLLGAATLGIKNVVCTSGHHQSLTGCSDSA
NVYDLDAIQVVWTIRQMRDKGTLLDGTAIAGKFSMLIGTVVNPYLRPMELNMIQLAKKIE
AGADFIQTQPIFDVEEFAVWLNAARQEGLADKTAILAGILPLSSVQEAEKLREAHTELRI
PDVLVAKLKAAGNADAQEKEG
>A0A2E0WXR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MPATNDLAAAYGSGRFGLSFELFPPKTDAGQQALERHVERLTEFSPSYITCTYGAGGSTQ
DKTLEVIGGVRRQHKLPVATHLTCVGRTREQLREYLDRGVALEVNNVVALRGAPPQGDDQ
FRPVDGGFSYANELVAFIRSELPQLGIAVGGYPEKHQEAPSLEVDLANLKRKCDAGADVV
ITQLFYSNDDFYRFRDDCERLGITTPIVPGLLPVTNGAQIQRIASLCGAKLPQKFVDDLN
ACGDDADAQFEVGVEFATRQTADLLESGVPGIHFYVLNKSEATSRVLTALNWPAPVQAKS
>A0A2V6V6P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MTNPLRVALAAGRFCYVVELVASALTREARLLETASGLARLPQVVAGSVTSYAGGAMGHD
PLRVAAAARARGLTPNIHLTCVSQDRGGLRKTLDDMHALSLENVFALTGDYPGAGDQPPV
FDLDSVQLVHLVDELRRGGKAFHVTVAVSPFKYTEADCVYQYVKLEKKIAAGADAAVTQV
GWDARKLEELKRYLDARGLRTPLLGNVYVLGPRTAERMATGRPPGCWVSPELLAAVRAES
LAQDGGRQARLERAARTVAVLRGLGYAGAYIGGTHDPVQIAWIIRRADELAPRWEALAAE
LRYGPAGGFYLSASAPRPRHPRRDALPRMLEWLGRALPVTRDTPLRRALARVFAWIDRHR
PAAVLLEHVELAIKKPLFGCQACGNCVLGHLEYVCPQTCPKQMRNGPCGGTDNGRCEVVP
DKPCIWVAVHDRAKASGSLDGLKTYVPPPHRQLRDTSSWINYFLDRDSRPGPGGG
>A0A2U3N4I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter stercoris|TrEMBL
MLYLPFMSIFSDYLDSQQFCFLVEFIASSKKSQIQSAHLAGFPVIAAIADRVHSDEDLSP
LQLAAELSENIEKMLHFSGKDRDIKDLNAFLQKAWQEKYLNILMLSGDKLKKHRFGNKQN
ALLRTRYLESVNAVTAAKATHSEFNIGVAFNPFKYADAEKSAQYFKLEKKIKAGADYIIT
QLGYDLDALQQAKDFLKEHQYTTPILACVMPLTYRRAKFMLDNKVAGVVITSHMLKILQQ
EYRLDPGFAEKMVYERAALQIYIAKHLGYAGIHLSACHQADQQQKLILALDKFRCLTLNQ
CLKLWEELWQIQQGDELKYPVLQPVEASSGQIAKYKSMHAMHDLFFSSKIAKGVGGLVFN
SKLWNKPKVADALLKTEFISKHRVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTTL
DRCEFGDRECIHSVKARLAKQLDETKMLRFEIIPTVPIEVRQTSSWKNWFSNE
>A0A2V6Q6F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFSRRLAEGPLLCDGAMGTMLYARGGAIDACFDVLNLNNPGLVQSVHKDYVAAGADC
LETNTFGANRFLLAAHNLEGRVREINRAGVKLARDVRESTGRDVYVLGSIGPLGKYLAPL
GTVSVDEAREAFREQADGLLEGGVDGFVLETFSDLTELAMAVEAVRSVTDLPVIAQMAFT
DEGMTFTGVAPDSVARQLRTLGVEAFGANCSVGSSVLYDVLERMLPEAAGVPLAIQPNAG
LPTRVGERLIYLSSPGYMAEYAGRMVEAGARIVGGCCGTTPAHVAAMREVLDRRAPSARR
APVRPVLVRPAPVAETPGLSAVRPPTALQRRLDGREFVVTVELDPPRGHGVDKLVQGAKL
LKERGVEIVDINDGSLGRVRMSVLATALLVRDGTGLDVNMHFTCRDRNLMGIQADLLGAH
ALDIRNILAMTGDPPRAGDYANATAVFDVDGVGLIEVLRRMNEGIDATGNSIGEPTSFCV
GAALNPVAEDLDREVERFHRKIQAGARWFQTQPVYDLAQLDRFLERAGGSPVPILVGLLP
LHSFRHAEFLHNEVPGITIPDAVRARLREAGDRALRVGIEMAQALVREVRGRYAGAYLMP
SFGRFEVVAEVLDAVH
>A0A2V6PEP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MLRRRLGHGQFVASIEFVTPEAHAPFETAIAPISEFAERIKADARFDTIALTDRVKSDHD
HDPVRVAAHVAEACGKAPLVHLSGKDRDASRVADSLRRMQGTGLENVLLVTGDKVRTSPP
GTPVRYHDSVNMIAQVRSSAADVFVAAAVSPFKYREEESMNQYLKMKKKENAGAHCFITQ
VGWDMLKFKELMAYRRRRGLTAPVMAGVMLLTVARARYIRANKLAGITITDELQARLEEE
ARQPDKGVGAAYRRLALQIVGLKRLGFAGFQLSGMHQLEKLDALFRRVEGLERGLANEGA
WWDAWWHALRGPDHGPTATAPRPYYLFKELAEPRGWGVANDQLTLRELDRAARPSAELKK
FRGLDRLDRLVFTEGSPGAALLKPVARLIAPRSALERGLHWLEQSVKEPVVGCQTCGFCR
LPYTAYVCPETCPKGLANGPCGGTTANVCEFGDRECIHNVKYRIARDTGRLAELEDFRGE
DPAVIRLSDIRAKGNRA
>A0A8C2Y893|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coturnix japonica|TrEMBL
MINSGCSTGSLLSSIISSHRHLAVCPVPTVLLLFPSSRALTMVNENQHTCSASSSSKSDG
GSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDRWFSLEFFPPRTANAAVNLI
SRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKDD
ITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVHGFNHAVDLVKHIRSEFDDYFDICVAGY
PKGHPEAESYEADLKYLKEKVLAGADFIITQLFFRSETFLKFMRDCQAIGITCPIIPGIF
PIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGLVHG
LHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYR
TQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVFTC
YITGEPNKNGHRVTCMPWNDDPLATETSLLKEQLEKVNRRGILTINSQPNINGKPSTDPI
FGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPN
AVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYY
LVNLVDNDFPLENCLWQVVDDTFELLNSPPQQ
>K4L6I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. CF|TrEMBL
MFISELFQQKKVVSFEIFPPKLTSSIEVIYDTIDALAPLRPDFISVTYGAGGSTSKTTAE
IASIVENKYNINSLAHLTCITSSKEQIEGTLTQLADSNVSNILALRGDIPKGSEETGRAR
DFQYASDLVAYIQDKHSFCLGGACYPEGHPECPDKDQDIENLRRKVDAGVGFLVTQLFYD
NDAFFRFQEKVANLNINVPILAGIMPITNRVQIERILALSNARMPQKLIKILDKFEHNME
ALKDAGIAYATKQIVELLANDIDGVHIYTMNKPQIAKDLVRNLDSLFYAVNSQETRKEGN
LA
>A0A3M6PYM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas spadix|TrEMBL
MIPVSFEFYPPKTEDQRAQLDRTAAKLKKYAPEYVSCTFGAGGSTLSYTAETVRHLQQHH
RFDAAPHLSCVGGSREQIRALLARYRAIGCRRIVALRGDLPSGMGHAGDLRHASDLIALI
RAEHGDAFRLEVGAYPETHPQASDALSDLKHFKAKVDAGADAAITQYFYNADAYFSFVDA
VRAMGVQIPIIPGIMPISNFSQLRRFSEQCGAQIPRWIDKRMAAHGDDAEAIREFGADVV
AQLCQRLVEGGAPALHFYTLNLARPSQLVLKRLGLG
>K8MW64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. F0442|TrEMBL
MTKQTPSLSFEVFPPNPEVGNAKLLRALENMQELAPHFISVTASNNKYNIKETTVALANH
IQNELSIPTIAHLPAIYLSKEKVADTLHELDQVGVHRILALRGDIIPGIEPLKDFRYATD
LIEFIKTEAPHFDVIGACYPEGHPDSPSQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVHHATKALFEHQPKLEVI
>A0A1F4F8I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_68_20|TrEMBL
MRSGDFVVTAEITPPVSTDPAEFVARAASLKGLATAVNVTDGAGAKAHLSSLVGAYFLAR
AGIEPILQMTCRDRNRIALQGDLLGAAALGIRNVLVLGGDEPMAGDQPDAKPVYDLDTRG
FLEMAHRMRSEHKLPPGTAIGGAVELVLGAADIPVDPPAGWNPASLRAKADAGADFIQTQ
FCMDIEVVRRYAARLLELGIAQRAAILIGVAPIPSARSARWMREKLHGTIIPEAIVARLE
GAADPKAEGRRICVELLQQLVEIPGVAGAHVMAPQSFPEIAAAIAESGVGRRKRRAAAT
>A0A087YIQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poecilia formosa|TrEMBL
MVNQVQQVDGSWQSCRGDSSGTSNSSAESSKESSRCSTPLLDADRSDRLREKMRKRMESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITSYLAKAKHLGLKNIMALRGDPVGDDWEDEEGGFNFAV
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEQDLQHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAVGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKIIEPIKDNDAAIRN
YGIHQAVDMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWVEDPRRPLPWAVSANPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LVQMWGEELKNEQSVFEVFTCYITAQPNRNGQKVLCLPWNDEPLAPETNFLKDELEKVNR
RGVLTINSQPNINGKPSGDPVVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGHNMTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWHVIDDMFELLDSTPEPLTDEAGS
Q
>I2H327|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 / UCD 77-7)|TrEMBL
MNIIQQSTPINASRKITELYKERTSPCVSLEFFPPKTEPGKRNLLDRIGRMSALEPLFVT
VTWAAGGTAADKTLELSTIIQQDLNIPVCMHLTCTNMDKTIIDEALEVCKRIGIRNILAL
RGDPPSGDDWLDFQMDQECDNFRYASDLVRYIKKNYDDYFCIGVAAYPEGHYGTDDDDTD
ADMEIKQDPIKDLPYLKEKIEAGADFVITQLFYDVDNFLKFEQVFREQIQNDSILLFPGL
MPINSFLLFNRAAKLSHATIPSSILDQFPVEIQNDDNIVKSIGIKILINIIEEIYAKTNG
RINCFHFFTLNLEKAIAQIVAKSTTLSSILEDSNVSDNHSTMPQIHRQPQPQSQLNNFPH
TVSNTELNESRNTDNDEDLILIDAEEDNSNNNRVTNGTTSTTYLEENKKRRRRRSSSTIN
YNDNDDNSRTTINRNSIPHNMNSTSNAININHSNMPSRKVLISISQGSGTLGRNATWDEF
PNGRFGDSRSPAYGEIDGYGPSLKVSYKKAIELWGKPLNFDDIKNIFIKYLEGSIDSLPW
SDLGLSPETGLIQEELIELNEMGYLTLSSQPATNGTSSTDKIFGWGPAHGVVYQKAFIEM
FISKNQWDTILKPKLDRYGSSKYTYYVGDVNGKFDSHQTYDSENNEYPNGNSDGSSSVVT
WGVFPNSEIIQSTIIEEESFKAWRDEAFAIWLEWIKLFPINSPTRIFLNKLRNEFCLVSI
VHHDFIKTDELWEMLLE
>A0A257SFS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium 21-66-5|TrEMBL
MGKRRVEVKPLLRQESLVYAVPTERKSRLAAKMCAGEKVTSVELVPPKSSDMTALLDRAR
KCAEAGVDAINIPDGPRASARVSPMISALTILQQVGIEPILHYCCRDRNLIGMQSDLLGG
YAAKLANFLIITGDPPKLGEYPDVTGVFDVDSIGLVQVAANLNRGLDIGGNPIDPPTGLF
IGVGANPCAVDLEREIERYFRKIDAGAEFAITQPVFDPEALLRFLDRVETYRRKIPVLAG
VWPLISFKNAEFMNNEVPGVVVPKAILERMSRCRTREDGRKAGIEIARGIVERISDRVNG
FQVSAPMGHVETALAVLGK
>A0A158KN47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia arvi|TrEMBL
MPPPESLIIMKPIELSFEFFPPKTQEGVDKLRASRAELKKLSPKFVSVTFGAGGSTQQGT
LDNVLDMAAEGFEAAPHLSCIGSSKDNLRAILANYREHGIRHIVALRGDLPSGMGEVGEL
RYASELVAFIRQEHGDWFNIEVAAYPEFHPQSKSPRADLENFARKVKAGANSAITQYFFN
ADSYFKFVEEARKLGVDVPIVPGIMPITNFTQLMRFSDMCGAEVPKWIARRLESFGDDRE
SIRAFGVDVVSGLCRRLIDEGAPGLHFYTLNGAWASKTICERLGFKSA
>A0A3B0C1N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ulvibacterium marinum|TrEMBL
MKVTDHIKKANGNTLFSFEIIPPVKGRSIQELYNNIDPLMEFEPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTVGICASIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFEPTKGGHPYAIDLIRQIQNLNCGEYLHEVVETDHCADFCIGAAGYP
EKHLEAPSLKTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVKQARAIGIDVPIIPGIKP
IAVKRHLQLLPPIFRIDLPQDLIDAVEVCKDNKAVRIVGIEWAIEQSKELKAAGVPVLHY
YSMGKSDNIKAIAEAVF
>A0A0G3C893|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina barkeri CM1|TrEMBL
MLFNFREKLNSSKFLVTAEVSPPKGTKFSVSLEDARQLKGIADAINVTDNQCSIMHMSSL
AFSKLLLDDGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICVMTGDFPSCGDHPGSKP
VYDLDSVQLLQLIRKLDSGINFAGNQLNGGTSFCTGAVSGIDPEKPLQLIKLEKKVRCGA
DFIQTQAVYDVGMFEEFTEAIGHLEVPVIAGLIPLKSLGMAEFMNKNISGIHVPEEIMLR
IKDAPDPVEEGLSIASETIKELMKLSRGVHIMPIGSHKNTARLLSMAGISGK
>A0A7W1V5V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriales bacterium|TrEMBL
MPKALPVTVTASPRRGLEPTLELTEELARGGYSAVPHLAARMLHDEWHLAEILARLDDAG
VRDVFVVAGDGEEPVGGFSDSLQLLTAIERLHRSGSGRTLESMGVSGYPEGHPLVAADEL
DRALLAKQPLSSYVVTQMCFDPGAVLGWIAHARELGVRLPVHVGIAGAVDRLKLLRVAGR
IGVGTSLRGAVALGGRMA
>A0A6P1QX54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bergeyella cardium|TrEMBL
MKITEHIQNADGKTLFSFEIVPPQKGVGISDLYKNIDPLMEFKPPFIDVTTSREEYIFLE
RENGLVERKVTRMRPGTLGICAAIQYKYSVDTVPHLLCGGYTKEETEYLLIDCMYLGIQN
VVALRGDAMKGEKYFKPALGGHSYASELVEQIDALRCGRYLNEDTGYKGCATDFCIGVAG
YPEKHIEAPSINYDLQMLKKKVDMGADYIVTQMFFDNQKYFDFVKKAREMGITVPIIPGI
KPVSTKKHLQLLPQAFKIDLPEPLINEVAKCSDNNAVRQVGIDWAVHQCKELLDFGVPVL
HFYSMGKSDNIYKIAKELF
>A0A1M5N3G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda flava|TrEMBL
MKVTDHIKAAKGQTLFSFEIIPPVKGRSIQELYGNIDPLMEFKPPFIDVTTSREEFVYID
RDGLLDKKLTRMRPGTLGICASIKHKYDVDTVPHVLCGGFTCEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFEPTSGGHKYASDLVRQIRELNKGNYLHEVIETDNCANFCVGVAGYP
EKHMEAPSLKSDLKRLKQKVELGADYVVTQMFFDNQKFFEFVEEARKMGIDVPIIPGIKP
IAVKRHLQLLPQVFRVDIPEDLIDAVEKCKNNKEVRQVGVEWCIQQSKELKEAGVPVLHY
YSMGKSDNIKAIAKEIF
>A0A0F2PS40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea sp. BRH_c9|TrEMBL
MSMSDVNPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRIGYAPIMQIACRDRNRIAIQGDVLGGAAMG
VGNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRIMRDNGKFLSGRKLTTPPQVFLGA
AINPFAPPYDFRPHRLAKKIAAGAQFVQSQYCYDVPMFRTYMQKVRELGLTDQCFILCGV
GPLASARTAKWMRANVPGVHIPDHIIARLEGATDQKKEGKQICIDIINEVKEIDGVSGIH
VMAYRQEEFVAEIVHDSGVLRGRKPWRKEPNPANELAEAHIEEARELPRQSPHELAGVAA
DGGE
>A0A1B8GML7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus verrucosus|TrEMBL
MHIKDMLNQGEQAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHA
QLTCEMVSVAQSVYGLETCMHLTCTDMGKEKVDDALKNAYKGGCTNILALRGDPPREKEK
WVATDEGFQYARDLVKYIRKTYGNHFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATF
IVTQMFYDVPNFLDWVRKVRAKGITIPIIPGIMPISTYASFLRRCNHMNAKIPPGWIEAM
EPVKNDDAAVREIGRGLVTDMCRSILESGINHLHFYTMNLAQATRGVLEQLEMLPSEERP
LKQALPWRQSLGLGRRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGEPKSVKDIANVFLRYLNADIESLPWSEAPISNEADVIKNQLVE
LNERGLLTINSQPAVDGVKSSHPVYGWGPANGYVYQKAYLELLVAPELIDELLDRIARDP
EVTYYAVTKSGTLRTNAPSDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHDSSSPSRNVIQRVMETFYLVNIVHNDFHQRDALFSLFEGLTVPNIDKAAEGTAAPA
AAPAPAAAAAPATNGDKVEEAPPAIVSNVLPVA
>A0A3D5A7W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp|TrEMBL
MKIVDHISNAKGKTLFSFELLPPAKGQGIQSIFKTMDALMEFKPPFIDVTYHREDYMYKK
HESGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDSDFIPTDGGHAFATDLLQQVVDMNQGQYLHEDIAISEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVTKCRENGIHVPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSEAVSACKSNADVRQVGEEWLVQQCKELIDFGAPVLH
FYTMSNPGPTXXYSKSTYLTISLPRKCSGLFL
>J6I6Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas sp. CM52|TrEMBL
MSKVSLELVPRDEAALREELAQTKKYEGKIDLINVPDLLRLPVRSWEGAAIAGETFPAVP
HIRAMDIDITKPLPMADYLREHAIREVLVIEGDAPQNMAHTVYPTESIDVIRKFREEMPE
IRVFAGIDQYRGSMRQEDYRIRRKLQAGAVGFFTQPFFDRRFLAMYADMLEGIEVYWGLS
PVTSQRSESYWETKNQVVFPKDFEPTLAWSVAFARDVLAEARAKGEHVYLMPIRTGIDEY
LGGIFAEG
>A0A2E2JU43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum sp|TrEMBL
MSAAPRISFEFFPPQSLEASFRLWDTVQTLAPMQPGFVSVTYGAGGTTRKLTHDAVATIH
KNYGLNVAAHLTCVDATREETLEIVNSYAEAGVTEIVALRGDPPKGQGHFTPHPDGFANS
IELVEALAETGKFNIRVGAYPDPHPESKGTGDDITWLKRKIDAGASSAITQFFFEKDTFL
RFRDKCVAAGIDAPIIPGILPIENWTGVRKFAARCGAYIPAWLDEAFEAAIRDDRHDLLA
TSLATELCTDLLDEGVEDLHFYTLNKPHLTRDICHALGVQPDVSLEKVA
>A0A554X838|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidimonas thermarum|TrEMBL
MALPLSFEFFPPKTPEGAAKLRAARHQLYAARPQFCSVTYGAGGSTQAGTVATVGDILAE
GVPAAAHFSCIGATRERVRRQLAELQAMGVRRLVALRGDLPSGYGLGGEFTYASDLVAFI
RAEFGAAFHIEVAAYPEMHPQARSPQADLQAFAAKVRAGADSAITQYFFNTDAYFRFVDE
AYALGVDVPIVPGIMPITNASQLLRFSDACGAEIPRWIRLRLQSFGDDVASIRAFGLEVV
TDLCDQLRTAGVPGLHFYTMNQAEPTLAILQRLGMLETA
>A0A2M7RV19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium CG_4_10_14_0_8_um_filter_32_5|TrEMBL
MKVIDHINKAKKPLFSFELLPPLKGKGIQSIYDGIDPLVEFNPSFINVTYHREEFIYKKR
EKGYLEKIAIKKRPGTVGICAAIVNKYKVDAVPHIICGGFSKEETENALIDLDFLGIDNV
LALRGDPIKTEPAFIPEKEGHEHAVDLVKQIVGLNKGIYMDEDLQNAIPTDFSIGVAGYP
EKHFESPNMKSDVNYLKQKIDAGADYIITQLFYDTNKFKKFVELCRKNDIHVPIIPGLKP
LSNKSQLISLSKFFHIDLPDDLVDAIEKCKNDEAVKQVGIEWAIQQSKELMEFGVPCIHY
YTMGKSVAVREIAKAIY
>A0A6N6RM23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeocystidibacter luteus|TrEMBL
MRINQHIEEAQKKDKTLFTFEILPPLKGQTIHDIYGNIDPLMEFKPPFINVTYHREQVVY
KRLSNGLLEQKVVRKRPGTVGICAALMNRYQVDPVPHLLCGGFSKEDTENALIDLHFLGV
ENVLALRGDGMQDQMYFVPEADGHTYASELVGQIVKMNKGEYLDEELANNAATNFSIGVA
GYPEKHFEAPSLNVDISNLKRKVDAGADYIVTQLFFDNSKYFEFVDKCRNAGINVPIIPG
LKPIATKKHLSMLPHRFHVDLPDELAMAVMQAKDNATVRQIGVEWATQQAKELKAAGIPV
IHFYSMGKSDNIYAIAKELF
>A0A1F3MJW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWF2_49_14|TrEMBL
MKVTDHISNRDRTRVSFEILPPTKGSSIKTIYDTLDPLMEFKPPYINITYHQAEIDLKLR
PDGLLEPKVVRKRPGTVAISAAILSRYQVDVVPHLICGGFSKEETEDALIDLHYLGISNI
LVVRGDANPLSGRFIAEKNGHENAIDLLRQTVDLNHGKYLEEDLVNPEPTDFCVGVAGYP
EKHMEAPNAESDLCFLKAKVDAGAEYIVTQMFFDNRKFFAFVDSCRAAGINVPIIPGIKP
VSIKKHLNLLPQTFKVDIPPALAREMDKCTTNEAVRQVGVEWCIQQAKELIQNDVPIIHF
FTMGRADNILKIARAIL
>A0A4V1BYI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus oxalaticus|TrEMBL
MQDRYFSFEFFPPKTAEGLEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYREGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVKAGADSAITQYFYNADAYFRFVD
DVRAQGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAAATKAIWQRLKL
>E5YMC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium 9_2_54FAA|TrEMBL
MSFFHANQREALNQSLAELHGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGGGKPDMYACDLVSLLKEVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMTNMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEIHAPI
TA
>A0A1W9QRI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium 4484_276|TrEMBL
MKVIELLKNTDKTLFSFELLPPLRGGNIESVYKVIDPLIGFNPININITYHQQEVVYKKL
PSGLLQKKTVRKRPGTVAISAAIKYRYPQLEVVPHLICGGFTKSETEYALIDLHFLGIEN
LLVLRGDPPKSQRLFQPDPEGHQFAIDLIEQITNLNKGIYQDDELRNKTATDFSVGVAGY
PEKHFEAANMDADLQYLKEKVDSGADYIITQMFFDNKVFFDFVERCRNFGIEVPIIPGLK
PISSMNDLRLLPLVFHIDIPEGLAAGLRKCKTNEAAIQLGIKWSVKQSLELKDYGVPALH
YFTIGVTDNIRQIAGKVF
>V7BLL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaseolus vulgaris|TrEMBL
MKIIDKIHEAAADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANKMQNIVCVDTMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVKHIRAKYGDYFGITIAGYPEAHPDVIGSDGLATAEGYQKDLEYL
KSKVDAGADLIVTQLFYDTDTFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPADIMSALEPIKDNEEAVKSYGVHLGTEMCKKILSHGIKNLGLIEESKISRSLPWRRP
TNVFRVKEDVRPIFWSNRPKSYISRTIGWDQYPHGRWGDSCNPSYGALTDYQFMRPRSRD
KKLIEEWVVPLKSIEDIYERFKMYCIGKLRSNPWSELDGLQPETKIINEQLERINSKGFL
TINSQPAVNGEKSDSPTVGWGGSGGYVYQKAYVEFFCSKEKLDTLVDKCKDRTSLTYMAV
NKEGSWKSNVGQTDVNAVTWGVFPAKEIKQPTIVDPVSFNVWKDEAFEIWSRGWASLYPE
GDASRKLVEEVGF
>A0A1S1Z3T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flammeovirga pacifica|TrEMBL
MKVIDRLIQAEREKKTLFSFELLPPVRGKSIQSLFDAIDPLMEFNPAFVDVTYHREEYVY
KELPNGLFEKSVQRHRPGTVAVCAAIMHKYNVDTVPHIICGGFSKEETENILIELNFLGI
ENILALRGDAAKGEASFTPHPKGYKYASDLVEHVDQLNKGEFMYSSESGFKGGFCMGVAG
YPEKHMDAGNLDTDIKYLKQKVDLGAEYIVTQMFFDNQKYFDFVKRCREAGITVPIIPGL
KPLTTKRQLTLLPNIFKLDFPQELLKEAEKCKDNKAIKQLGIEFGIQQAKELMEFGVPSM
HFYSMGRSTSVKDIAEAIF
>A0A3D1HIV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp|TrEMBL
METEHKSYFSFEVLPPLRGKGIDSIYRTIDRLMQFNPEYINITTHRYETIYSELENGMYE
KLSVLNRPGTVAISAAIKERYGVRTVPHIICSGFTAAEIESELIDLSYLGITDLLLLRGD
RPRGENKYITIPGGHTHAIELCEQVNRFNSGQLLAGAHSEGPVTPFSYGVAGYPEKHDEA
MNYDIDIDYLKQKVKAGASYIVTQMFFDNKKYFAFVKRLRDEGINVPVVPGLKPLTTLGH
LTMLPKTFHIDFPKRLSAELMKCKNNDDVKQVGVEWAIKQCRELREAGVPGIHFYTMNAS
QSVEKIMNGLHQ
>A0A8D5UH51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polycladomyces abyssicola|TrEMBL
MSGRDLRQCLQNGLLVGDGAMATYLYQQGIPVGICYEELSLTQPDVIRSVHRAYYEAGAR
LIETNTYGANRERLERYGLAGKVTRINREAVAVARSAVDDDAFVVGSIGSILAGRVPHYD
TEAYRDMYEEQATALLHAGVDGIVLETFLDLEELLLAVEVIRPLTDRPIIAQLALMEVAR
TRDAYTLDGAFAHLAKSGVDGVGFNCRLGPTELLRALEQTVMPTDLWISVFPNAGRLGLV
DGNYEYQTSPAYFGESALRLREQGVRIIGGCCGTTPAHIRAMAESLRDLPPLPRVNPKNK
TESSARRVPIHLRQRNKPTIVERVQREYTVIVELDPPKDLETSSFLEGAARLHAAGAAAI
TMADNSLATTRMSNMALGAIVKSQLGIDPLVHITCRDRNLIGQQSHVMGLHALGIDQVLV
ITGDPTRIGDLPGASSIYDVTSFELIRMLKQLNEGISFSGKPLKQRAQFVVGAAFNPHVR
HLDAAVRRLEKKVEAGADFIMTQPVYDADGIRQIAEATAHLDIPVFIGIMPLTGYRNALF
LHNEVPGIKIPSDVLERMKDLKGEEGRKMGVAIARELLDVAMAYFRGIYLITPFAYWQMT
EELTRYVLRAKQNALVQSAGGQG
>A0A8H6LQ27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. conglutinans|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDDVKGDDERVKMVGVDIVSELIDKIKTIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A2Z5EDR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. P6W|TrEMBL
MTAEARAAETPLFAGLPGDISVSFEFFPPKSEKMEEQLWDAITQLAPLDPSFVSVTYGAG
GSTRERTHSTVSRIVRETSLVPAAHLTCVAASKAEIDEVVDQYWEAGVRHIVALRGDPPP
ADGGRFVPHPEGYASAAELVEGLKKRRDFEISVAAYPEVHPEAVSAADDLDNLKRKLDAG
ASRAITQFFFSTDAYFRFMDKALAAGITAPILPGIMPVTSFAAIRRMSGNTLIPDWLETM
FDGMDTRPGPRALVAAVAAADLCKRLYEGGVRDFHFYTLNRAEQAYAICQLLGLRPKA
>A0A4U6D9Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter frigoris|TrEMBL
MTKVTEFIHQAQGKTLFSIEIIPPLKGQNITELLDSIEPLMEFKPPFVDVTYHREELIDV
KGQNGLIERIPIRKRPGTVGICARLMERFKVDAVPHVICGGFTKDETEDVLFDLHYLGID
NVLVLRGDPEKSAGVFKAKLGGHTYASELVVQVDKMNKGVLLHAETEAAHTNFCIGIAGY
PEKHFDAESLDTDFEHLKRKIDLGANYIVTQMFFDNQKYFRFVDRCRAEGITVPIIPGLK
PLATKRQLTVLADIFHLEFPQELVKEAEKCATDKEVRQLGVEWGVQQCKELIEYGVPVLH
FYTMGKSDNVARIASQVF
>A0A0D2GAY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cladophialophora bantiana CBS 173.52|TrEMBL
MHISKKLALAHQQNKPTFSFEFFPPKTAQGVQNLYDRMDRMHNLGPAFIDITWGAGGRHS
QLTCEMVNATQNYYGLETCMHLTCTDMERHQVDEALRRAYKAGCTNILALRGDPPRDQEK
WEAKEGGFRYAKDLVKYIKARYSDHFDIGVAGYPEGCDDQRDVDLLIDHLKEKVDAGASF
VITQMFYDVDVFLNWVKKCRARGINVPILPGIMPIQTYAAFVRRANWTKCHVPPEWFDAL
EPVKNDDAAVRAIGKDLVADMCRKILDVGILHLHFYTMNLAQATRMVLEDLSLTPETSGM
RLEKPLPWRQSLGFNRRDETVRPIFWRNRNASYISRTADWDEFPNGRWGDSRSPAFGELD
AYGTGLKGTNEANIKLWGKPRSLRDVTGLFVRFLQGDLDRLPWSEAAISAEADSIKDDLL
KLNKHGFLTINSQPAVDGASSTHPVYGWGPAGGWVYQKAYLELLIFPSMFKTIMERLDAN
KNLTYYAVNRKGELYTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WAKCYPAGSGSRKLIEKIMDECYLVNIVNNDFHQNHEIFKVFEGLEAQDLDVVVEDTVPD
HPGNGTRHVLDGDASVTSAEKSVTNGEQNKVPSKASGEALTN
>A0A3Z1E8M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7G6U933|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tardiphaga robiniae|TrEMBL
MMSVKPGEILRDFSFEITCKDISKLDSLMRVAAPGSLVSLTFLPNEDVAARIAAASAVRA
AGFVPVPHIAARRLASPEELEHYLEALVSRAGVDRVFVIAGDVATIKGPYPDALSVLRSS
LLNKYKIAQVGISGYPTGHPKIPDGVLWQAMRDKLAILADMGHRAWIMTQFGFEATAILD
WLARSRLEGNNVPVCIGVAGPSSVRSLLHFAALCGVETSAKVVAKYGLSIGKLLGSVGPD
AILKDLASGLNVPMHGPTAIHFYPFGGLGSLGRWIEEFRRSSEVEVVSRLSAR
>A0A256ZWI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon ex4484_162|TrEMBL
MSIELLRDIIKKNKFPITFEPDSPKGISIEEKFPKKIIRKISAFGVYNNPRGRPKLDPFV
YGWMLKEKYKKDVIVNVRIQDYSIPLFQSILWGGHLLGLRNLLIITGDYYPGSPFLIDVT
EGLTAVKDYLNNGYIIPELNGKARRYYNRLKEKKYIKRENKVIDGKTDYFVGAALIPTRK
KEIEIYKKKIDAGAQFFITQLTYDSKTVTDFIEKVDPSVPILVGSGPITSLKRLEFFKKQ
LGIPGLSDGIARILREAKDMGEKSVEICVEMYQNLRDFAKSNGYTIGAHVMSIKYPSLAA
KIIEEIAKL
>A0A846LNY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter marinus|TrEMBL
MTGTVRELLQTERPTWSFEFFPPKDAAAETQLWTALRQLEQLRPSFVSVTYGAGGSTREG
TVSVTERIATDTTMLPLAHLTAVDHSVPELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WVAHPQGLRYAAELVELIKGIGDFCVGVAAFPERHPRSADFESDTDMFVAKCRAGADFAI
TQMFFRVEDYLRLRDRVSARGCDVPVIAGVMPVTNARQISRIVQLSGQAFPAELAERFAA
LDGDRPEDKRAVRELGVEVATQMCRQLLDEGVPGIHFITMNRSTATREVYANLAGADLVS
>A0A3R6QSK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. AF25-25LB|TrEMBL
MNIKEYIKEQRLITDGAMGTYYEEKYSEDTVIAEKENLKNPEQIKEIHLEYLRAGARLIR
TNTFAANTMFLADMQEVKETVRAGYEIAKEAVASFQAENGKEIPVFIGADLGPIYDLDHQ
DYDNVLQEYKEICDTFLSCGADCFVFETQSDFTYIEPVTAYIKEKSDAFILVQFAFDKSG
YTRSGLSMQRVAVEASEMENVDAYGFNCELDSTHMYQFMKNLKFSSDKFVSALPNAGYPY
TLRGKTIYSNNASYYAEKMKDIAALGTDILGGCCGTTPEYIALLSGELQDVPKAAKKIEN
VVTQEVTRTPSIFEEKLSRGEKAYIVELDPPFSEDASKVMKGAEDLRKCNVDLITLSDSP
MARARMDAGQLAVKIQQKTGVAVMPHISCRDRNVIALRAGLLGMHMNDVRHFLIVTGDPV
SRADRERVTSVFDFNSIKLMQYVKEMNLEVFAQEPVYYGGALNYHGANPDAIIERMKRKA
EAGCGYFLTQPVYTEEDVERLTYIKEHIDTKIMCGIMPLVSYKNAMFVKNEMPGIHVSDE
IVNRYREDMTREEAEEVAIELSVEIAAKLYDIADGFYFMTPFNRTGLIARIIEAIRQEEE
RR
>A0A8G8QNK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMB3-15|TrEMBL
MTATPTTPPTDPDCRSSIPFSFELYPPKTDAATMALHATIDALAAARPKFISVTYGASGS
SRTSSLDVLRYIRRATIVDPMAHLTCVGSSHAEASSLIREFLDAGVSSFLALRGDPPEGL
TENDAFLGDLHSAGELVQLIHRVQAERVPYQETPIPGLPRARAVKTEREHVRIAVAAFPN
GHPRSRSTAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPV
TSPGRLRRILELSGEELPAELSIQLEVEPTLEGQREIGVSHAAALAEKLIAGGAPGLHLY
AFNQHETVLAVLDRAGALAPAQPVVSAHNPPPTHPSTSPADTRAGIHSTKDHY
>A0A842ERZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDTGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVAEQIISQN
>A0A842GEX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMSIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVAEQIISQN
>A0A841Y939|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGCNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDEAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVAEQIISQN
>A0A2S6R6F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha10_Bin2|TrEMBL
MKDNKAGAPLSEGNLETVLRSGQFALTAETAPPDSADPEAVLARTGCLKGLADAVNVLDG
PGAQTHLSPLAAAAIMARAGIEPVLQFTMRDRNRLALEADILGAAALGVPNILCLTGDSP
EAGDQPEAKPVFDLNSAQFMQIIDDMRRKSVYPGGRTIETPPRLLIGAADSPRKLDADFS
PASLEAKIDAGADFFQTQYCFDMDILRDYMARLSDLGILERTHFIIGIGPIASARSARWM
NENLFGVHIPEPIVARLEQADDAKAEGRRICVELIQQLREIVGVSGAHLMAPHGEQAAAQ
VITDCGVLENRAA
>D5CU81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sideroxydans lithotrophicus (strain ES-1)|TrEMBL
MINNTKTPISFEFYPPQTPEGVEKLTGVRQRLAAVKPEFFSVTFGAGGSTQDRTLETIRH
IHAEGHSAAPHLSCVGSTRDNVRALLFAYKDMGIKRIVALRGDLPSGMHSIGEFQYANEL
VSFIRAQTGEHFHIEVAAYPEFHPQAKSAREDMLNFKRKMNAGANSAITQYFYNADAYFR
FVEETRKLGVTAPIVPGIMPIGRFSQLARFSDNCGAEIPRWMRKTMEGYGDDSESVQAFG
LDVVTQLCEKLIAGGAPSLHFYTLNQANASLEILKRLGYR
>A0A2M7PJI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium CG_4_10_14_3_um_filter_42_6|TrEMBL
YRFGIDVVPHIICGGFTREETENALIDLQFLDINNVLVVRGDPQPGTRIFVPEPDGNEHA
LDLVKQITNLNKGIYLDADLLNTRSMNFCIGVAGYPEKHGESPNLDSDLYFLKKKIQAGA
SYIVT
>A0A1Z9H6F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium TMED154|TrEMBL
MNNNNTFKWSLEILPRHVGEVHQLPQWVEEIYVTMIPGSDISEVIQASADLVEQGRTPIP
HIAARGLESAEEFSSMLESLKQKGVRHLLLIGGGVEDQEGPFTEVMDLMQTGELQRVGFE
EIGIAGHPEGNPSDPDAENSLLRKTKWAEELGIPTRIVTQWSFDSQVVNEWIGRLRDQGV
NNPIHIGIPGPATLKTLIRYAQVCGVRASTEVLKKQGFNLGKLLFVNKPDRMVREIQGHQ
QLHLFPFGGLGKASEWLEQQQNLASAA
>A0A2P9AWR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium delmotii|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>Q6CG63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yarrowia lipolytica (strain CLIB 122 / E 150)|TrEMBL
MKISHKLEKAHAADSTPTFSFEFFVPKTSQGVNNLYDRMDRMYQLGPQFIDITWNAGGRL
SNLTNEMVATAQSALGLETCMHLTCTGMPKQLVENALQSAFDGGCQNILALRGDPPVESE
KWEAVDGGFRYAKDLVKYIKSKYGDYFDIGVAAYPEGTPEEPDVDILIDHLKEKVDAGGT
FIVTQMFYDTDNFLKWVDKCRAKGINVPIIPGIMPISTYASFMRRANWCQIQIPQDFLDQ
LEPVKDDDMRVRELGTQLVADMCQKMLDSGKIKHLHFYTMNLEKATVMVLERLNLPAQDS
AVAPLPWRPSLALGRQDETVRPIFWKNRKQSYVARTQDWDEFPNGRWGDSRSPAFGELET
YGVLLRQSPQKVLELWGEPKTVDDLKTLLVNYLNGKLASLPWSDVPISNEIETIKPQILE
LNNRGILTINSQPAVNGAKSTHPVHGWGPKNGYVYQKAYLELLVTPEVAEKLVKKLENQS
EITFYAVNKTGNLQTNAPGGPNAVTWGIYPGKEVIQPTIVEKISFLAWKEEAFRLGSEWA
KCYPAESESRKFLDDIFNNWYLVNIVHNDFHDSTGIFDLFSDL
>A0A1D8K748|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidihalobacter aeolianus|TrEMBL
MRISVELIPRNAEDLLNDARTVRSVMPQATAFNIPDLIRFPMRSWEACKLTKNILPASIP
HIRAIDIPPVGDPPMAEDILATGLQEILVIRGDPPHDLSHRTYPNSSEDVIRRFKQCCPN
VRVYAALDPYRLGFRDELTAIHRKLDAGADGFFTQPIFDLRLMAIWAEMLQGHNIFWGIA
PVLGDRSRAYWETTNRVVFPSNFAPTLEWNRNFAAKAVRAARDFEGNVYFMPIRVDLAAY
LAGLVTD
>A0A075UQJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis japonica|TrEMBL
MDLVRRIDRAAGEFLLFALTPPRLATARERVQEIADATMARLRPLDLDGLILYDIDDEAA
RNPAQRPFPFSPTLDPANYLADNFTSWQTPVIVYRAVGKYAPSELRTWLAAQDPARVMTV
LVGASSSKIDTMTSLADAQALRRDVNPGLPLGGVAIPERHSRRDDEHLRLLAKQDAGCRF
FVTQVVYDVNAAKNLVSDYHYECVARGRTPVPVVFTFSVCGSLKTLDFLQWLGVDVPRWM
ENDLKHAADTLEASYQLALAAATELMAYCRGLGVPFGINVESVSIRREEIEASVRLAEQL
RTEIKG
>A0A659UPN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.158.01.1.1|TrEMBL
MEKAAIRPSSIDASIEMAPSQVIDSPDLPGLFPSGVRVYITDIGLADTPTLVKAARRVAD
LGYTAVPHMAARRLTTRQALETRVKALAEEAGVRDLLIIGGDVATPAGSFSSSFEVLQTG
FVDKYGITEVGIAGHPEGSRDFGDEAAIAALRMKSAWAERTGAKMRVVTQFGFDADKFIA
WADGLAVSGVDLPIHLGVAGPAKITTLLKYAALCGVGNSLNFLKKRSASLAALATSHSPE
SFVGPIEHHLRAKPESAIAQLHVFPFGGIKNTARWLYERGSWQGLEADDRSSIA
>W0ERU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Barnesiella viscericola DSM 18177|TrEMBL
MKVADLLRTHGSTGFSFEILPPLKGSSIEKSFKTIDTLREFDPLYINITTHRSELVYKDT
PDGLFRRVSERSRPGTVAVAAAIKNKYQIPTVPHMICSGFSAHETEYALIDLNFLGICDL
LILRGDKAKHESRFTAVPGGYEHAIELEEQVNRFNEGYFIDGTPMDVVSSRPFSYGVAGY
PEKHDESPNPEEDMKWLKAKVDMGADYVVTQMFFDNSKFFDFVDRCRAMGITVPIVPGLK
PISKASQLTLLPRVFHVDIPDALVREVAKCKDDTQVKQVGIEWCAAQSRELKARGVPSIH
FYSLMAVDSVYQIAKQVY
>A0A2H1XZZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum finnmarkense|TrEMBL
MKVTEHIKKSNGKTLFSFEIIPPKKGNNIQDLYQNIEPLMEFNPPFIDVTTSREEHLYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFSKEETEYLLVDCHYLGIEN
VMALRGDAMSHQRYFEVSKGGHQYATQLVAQIKNLNQGKYLHDVIEANHKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVKHARKMGITVPIIPGIK
PISVKRHLQLLPQVFKIDLPQNLITEIEFCKNNQQVRELGIAWAIAQSQELLKAGVPVLH
YYSMGKSDNIKAISKALF
>A0A1C4KDM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SolWspMP-5a-2|TrEMBL
MLAAGETTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRSGTVRATER
IAADSTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWVPHPEGL
TYAAELVRLIKESGDFCVGVAAFPERHPRSTDWDTDIAHFVDKCRAGADYAITQMFFRPE
SYLRLRDRVAAAGCETPLIPEVMPVTSVKMLERLPQLSNAAVPSVLKERILTAKDDPAAV
RSLGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLGLHHPPRA
>A0A1A0JN44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria sp. ICS0012|TrEMBL
MPAPLAASEPAPVTGPPTGTSWLVRRPRRSTLVSFEVFPPRPTADPDTVWRNIDAMAQAG
PDFFSVTHGHAGHHGVSREALRHLRRTTKTPVMAHFTCGGTDRAGLERAVDQLLDDGVRD
LLALRGDPPLGTGAWRTPAGGLGRASQLVELIRDVERRRFGTGFRPGQRPLSVSVACYPS
PARGRDFEADLASLWDKQEAGADYAITQVLYEPEDYATFLERARSEGIHIPVVAGLMPLS
NPQRLQRMTEITGVRVPERLTRFLRADTPEELRHRGVAATLSLIDDLMDLGCAGFHLYTF
NRPEAALTILEHLRVRDAAREYRGRSPAA
>A0A178JAY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio europaeus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASRGELIQIADDYWANGIQSIVALRGD
IPPGGGKPEMYASDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPTA
>A0A2R6DKZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QH_6_64_20|TrEMBL
MSLQTPETTADGVSTLLAEPRFELMPFDSFGEQMEHLPDGAEIAITTSPSLGLDATLEWS
ERATDRGFEVVPHIAARYVRDEEHLAEIAGRLAEAGVTDIFVPGGDREEPVGKFDSAYEV
LAALDDSEYEFEEVGITGYPEGHDFLDDRTLAEAMAKKEPYATYIVTQLCYDSDAVIEWI
EGIRARDVELPVEVGIPGVMKYQRLMEISQKVGVGDSVRFLRKTTGILGFARQLVGSRGK
YTPDDLIEGLAPYADDPDYGIRGVHVYTFNQTPDTEDWRRRTVGGDR
>A0A023PAZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus bombysepticus str. Wang|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7I0RFA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. CGMCC 11546|TrEMBL
MGWSSFWDNSGADGDVVRSGNILAGWSIEVMPRTAAKIDDFRNILPDGTRVYIAHIDGTP
IADMVSTAKRLHDEGFPVIPHLPARGIGGKNELEDWLKRYQGEAGVTQALLLGGGQKQPA
GSFSSSIDMIETGLFDKMGFTHLHLAGHPEGNRDIDSDGSSRGVDQALLWKQDFASRTDA
RLALTTQFAFDAKAVIEWAKRIGNMGVTIPVHVGIAGPTKLQTLIKFAIACGVGPSLKVL
QKRALDLSRLFVPYEPTDFIAELIDHKAANPDSLIEHVHIFPLGGIKPSAEWMKKHASTG
TLANVA
>A0A7K7ZMK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melanocharis versteri|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A4S8N4R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium rhizophilum|TrEMBL
MAHIDENPLGPHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VTNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLSTPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMNKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDHVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGILKGRKPWKREHARADDIAAQRMQEIGEDPVQDQQEMAGRAA
QSQTH
>A0A359FZ70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinilabiliaceae bacterium|TrEMBL
MKTAAQLIRELEKPGFSFELLPPLKGNSINGVYNTIEQLKEFNPLFINITSHRDEVIYRD
IDKGLFERRITRKRPGTVAVAASIQHRYGIKVIPHIICSGFTKSETEYALIDLNFLGIHD
LLLLRGDRPDRKSPLVELQGERNEHAIDLIKQVNSINKGVFLDDTQADAFETPFSYGVAG
YPEKHEEAPNIDSDIYWLKKKVEAGAEYIVSQMFFDNSKYFEFVKRCRDAGITVPIVPGL
KPLTFLNQLTVLPKIFHVDIPEAFAKELRRCKSDEEAASAGVEWTIMQAKELLSGGVNLL
HFYTLMATRSVKEVAAAIY
>A0A1M5DS41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWB8|TrEMBL
MKIVDILKQDKMSLSFEVFPPKKETSFESVKAATESIAALGPAFMSVTYGAGGGVSHFTL
DIAKNLKQKFGIPMLAHLTCVSSSKETVHQRIEDMKAAGIKNVMALRGDLTPELIEKGRD
NCDYHYAVELIRDLKAADADFCIGAACYPEKHPESANQAEDIQHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFK
>A0A5J4J8X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Patiriisocius marinus|TrEMBL
MKVIEHINNANGKTQFSFEILPPLKGQNITQIFDQMDPLMEFKPPFVDVTYHREEYVYKE
LENGLLQKKIVRKRPGTVGICAAIQNKYQVDAIPHILCGGFSKEDTENFLIDLGFLGIDN
VMALRGDAVKSETYFTPERDGHSYAGDLVQQISELNMGKYLDAEIENQAQTDFCIGVAGY
PDKHLEAPSLDSDIHFLKKKIDKGATYIVTQMFFNNAKYFSFVDKCRAAGITVPIIPGLK
PLATKKQLNLIPHRFSLELPDELIADVVKCKDNKAVRELGVAWCIQQSKELIAAGVPVLH
YYSMGKSDNIRAIASSLF
>A0A2N6F1T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MGNADFLQRLREAVIVGDGAMGTQLYSRGVPADSCFERLNLIQPDLVVSVHEAYVQAGAQ
LLETNTFTANGVRLGGVGLDRQVRQINESGARLARQAVGSNGCFVAGSVGPLGHRDSEEN
LSVDDQKALFREQMTGLVDGGVDLLLLETFASLAELQTAACVAAEFGLPVVAQMAFFAEG
RTREGLDGKAFARALEGTVDVIGANCGVGPHEMLQLVRQMTGATTTPVSAFANSGFPQYV
NGRHVYLATPEYFAARGLEMVEAGAGLVGGCCGTTPEHIAALTALIRGVKPSRSVVPLQT
EVSKPTPVRVAEPRRMTVSPLLDPARKSVPVTVELDPPRGLDCSVTIERAKLLARSGVDA
INLAENPLARIRMGNLALAAKIQDATGVPVIAHVTCRDRNLIGLHSDLMGAHLLGLRHIL
AVTGDPVSVGEASGATSVFDLNSVGLLQLLSGLNQGRNMLGAELGEGTCFCLGGAFNPNV
AQLDGQVRKLKKKWAAGAQFFQTQPVYSVQVFHRMTEALTDVSAPVYLGLLPLVSERNAE
FLHNEVPGIVLPDEVRKRMRGTSGKSGVDAGMAIATDLIRNCAAQADGYYIMPPFGKVDM
AIELIENIRSISSTAP
>A0A4R0FIG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 3781|TrEMBL
MSQLSSCFQNNQFCILVEYLTSLNEIFPVKTEFARYPAVMTLADRVHSDHDVTPLAASEQ
YPDSVDKILHFAGKGRDIQDIELFLQQAKAAKIKNLLLLTGDKLKEHCDGKDGAERSRYL
ESVNAVMAAKQFGGFCIGVAFNPFKYAEAERDAQYLKLHKKLKAGADFIITQLGYNMDAL
KQAKIFLNHHQYTQKILACVMPLSLARANFMVKHQVAGIVITPHMLQVLTDEKQTGLNER
VYLRCALQMLMCKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLTLDELESLWNSLWQVK
TGKEFVPELPYYSCQPTSSQIIKYQQLHFMHEVLFESKIAKGVGRFIFRAAWWENTPAAK
ALLKTEYISKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVEQTEVLKEKLIPTVPIEVRGTSSWKNWYAATEA
>A0A7C5BGL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
GALGSSQENSKEAVYTLIKEKDLTVMPHITCIGASKEKIKNLLDEYKNIGIENIMALRGD
IPKDVSDFSFSKDFKYAKDLVKFIKENYKFCIGVAVYPQGHIEDKSFKLHLEYTKEKIYA
GADFAVSQMFFDNKYYYSFLEKIKKIGINIPVIAGILPLTDIMKAKEFCSVCKVTIPKKI
EKKMLKFIDKPLDLEKIGLDFTIKQCRDLIKNGVNYIHFFTLNKPRVIKKVLEGLI
>A0A2U9SFZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. JP2-270|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTDLCRRLIDAGVPGLHFYTLNAAAATRTICERLAV
>A0A136P8E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobi bacterium OLB7|TrEMBL
MPRGVEMEHLFESAEYLHQHGIDAVNISDGARARLRMSSITISHLIAQRTGMECITHLSC
RDRNMVGLQAELLGAHALGLRNILAVTGDPTHIGDYPYATSVYDVDSVGLIRTLTRMNGG
EDLMGNPVGSGGTNFMVACAVNPMAFDIEREIERLERKVAEGAHVAFTQPMFEAATVRQL
LSRTEHLNIPIMVGVMPLRSALHAEFLHHELPGMFIPEAIQQRMKGAAQPLEEGVEIAVE
FLQSIADVRERIAGMYIMPPGKRFDMIVEILRRMQG
>A0A2D5WTG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium|TrEMBL
MTTLSFEFFPTKTEEGTEKLLKVRDELAAFNPEFFSVTYGAGGSTRDRTYAIVKAIQERG
IAAAPHLSCVGDSKEDLRSLLNEYKDLGIDRIVALRGDLPSGAGLASSELRFANELVEFI
REETGDHFTLEVAAYPEMHPQATSFESDLERFVNKVKAGADSAITQYFFNADSYFYFVDR
VRDMGVDIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDNTESIQQFGEEVV
TEMCHRLLEGGAPGIHFYTLNQSEASLRVWRNLI
>A0A1V5SF87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium ADurb.Bin292|TrEMBL
MRISSFYQTGRPAISFEFFPPKTPEGEQKLYASVAELKELKPSFVSVTYGAMGNTQANTL
RVVTEIQNRIGIETAAHLTCVAHSRDEIAGILGKLAEAHIENIVALRGDPPQGETEFRPA
PDGFRYASELVSFIRSHRVYGRAFDLVVAGYPEGHPECRDLEKDLEHLKIKVDSGADAIN
TQLFFDNRDYFRFVERARKAGIRIPIVPGIMPVTYGPQIEKFSKMCGAKIPLEIREAIEK
FGDDQSSILRFGIDYAIRQCRELLAEGAPGLHFYTLNQSCATREIYAHLGLPR
>A0A1G0B3K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteria bacterium RIFCSPLOWO2_12_FULL_35_11|TrEMBL
MKVTDHIKQAKGKTLFSFEIVPPQKGQNIQELYDNINPLMEFKPPFIDVTTSREEHVYIP
KEKGLLEQKITRMRPGTVGICASLKYKYNVDAIPHVLCGGFTKEETEYLLVDCHYLGLDN
VMALRGDAMKHEKYFEQTVGGHKYARELVTQISDLNKGKYLHEIMETLYKPDFCIGVAGY
PEKHMESPSLDADLRRLKEKIDAGADYVVTQMFFDNNKFFEFVQKARAMGITVPIIPGIK
PIAIKRHLQVLPQVFKLDLPEALISEIEKCTNNEQVRQVGIEWSIAQSKELVANGVPVVH
FYSMGKSDNIKAIAKEVF
>A0A011PG94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter sp. SK-11|TrEMBL
MTTTAPTFSLELFPPQTPEGADKLRAARAEMALLHPRFFSVTFGAGGSTRDRTLETVLEI
QQEGHQAAPHLSCIGSTRASIRSILAQYRTHGIRHLVALRGDLPSGMARPGSFRYANELV
QFIRSETGSWFHIEVAAYPEYHPQARTPLDDLLAFQRKIDAGADSAITQYFYNFDAYAHF
IDECQAVGINVPIVPGIMPISSFSSLARFSDNCGAEIPRWIRKRLESYGDDRASIQAFGL
DVVTQLCERLLAAGAPGLHFYTLNQVGLTRTLWQRLGLTSPVEA
>A0A4Q1KYV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium piscinae|TrEMBL
MKVTQHIENANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPSGLLQKKIVKKRPGTVGICAGIQNKYEVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKNEIYFKPEKEGNEYASELVTQIHNLNKGIYLDEDLQNSSCTNFCIGVAGY
PEKHMEAPSMDSDIHFLKQKIKNGADYIITQMFFDNQKFFDFVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNDAVKQIGIEWCIAQSKELVAAGIPVLH
YYSMGKAENIKAIAKEIF
>A0A1V2VJV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. VT-16-41|TrEMBL
MSTHNFSIEFFPPKTAEGAQKLRATRARLAQLQPRYFSVTFGAGGSTQQGTRDTVLEIIG
EGHQAAPHLSCIGSSRASLRAILDDYRANGIKRLVALRGDLPSGYGAMDQASSEFRYANE
LVEFVRAETGDWFHIEVAAYPEMHPQARSPEDDVQNFARKVKAGANAAITQYFYNADAYF
RFVDEAARLGATVPVIAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTESIRAF
GQDVVTQLCERLLAGGAPGLHFYSLNQAAPTEAIWQQLVK
>A0A352R474|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium|TrEMBL
MQVSFEFFPPRDNAGQSSLDNAVQQLQVWQPQFASMTYGAGGTSQQESFAGAQKLLARDL
ATASHITCVGADRETVQATAKQFVAQGVDHFVALRGDSPDGPYVPHPQGYAYANDLVAGL
REWFTGTISVAAYPEIHPQALSGAKDLAFLKAKMDAGADQIITQYCYNTDTLLAFAENLQ
KVGITQPLLVGIMPIHDIAAVQRFSARCGATVPQSIGDRFAALEQTQDKVKLAIDIAVEQ
CRQLMENGLDQFHFYTLNRSTLTAGVLATLEQPPVNMALSA
>F2C884|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sanguinis SK330|TrEMBL
MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE
FIANDLKIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDAAPKDDFTYAT
DLIEYIKTEAPHFNIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHHPSVQSF
>A0A2N6EU99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MLMKEILDQGRISLSFEFFPPKTPTGWERLFENIADLSPLAPSSVSVTYGAGGTTRSQTH
ELVLRIHKETGITVVPHQTCVAATRGDVTAILSEYEQIGIENVLALRGDPPQDDPDWTPP
QDGFHHAIDLVKFIRERFPRFSIGVAGFPEGHPEMPNRLLEIDYLKQKVDAGADYIVTQL
FFDNRDFYDFCERCRLAGITVPIIAGIMPLRTRQGMLRMAELAAGARFPAALLKRVAEAE
HDEEVECIGTEWAIEQVKDLVAHQVSGIHFYTLNSATATCEIFSRLGLC
>A0A2N2ZM86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-13|TrEMBL
MKVTEHIESANGKTLFSFEILPPLKGQTIQSIFDHIDPLMEFKPPFIDVTYHREEYDFNE
LPNGLLEKKVVRKRPGTVGICAAIQNRYEIDAVPHILCGGFTKEDTENLLIDLGFLGIDN
VVALRGDAVKSETYFKPEKEGHAYAEELVKQIIAMNRGKYLDDSLENSAQTDFCIGVAGY
PEKHMEAPSLESDFHFLKKKIKNGAHYIITQMFFDNQKYFDFVDRCRKEGIDVPIIPGLK
PLATKKQLNMIPHRFKVDLPDDLVMEVVRCKDDKAVRQLGVEWCVAQSKELIAAGVPVLH
YYSMGKSDNIQSVAKTVF
>A0A6A4UAV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MKVIEHLEKSNNPLISFEIIPPKRGGNVKQLLHVLDDIVKYHPPFIDITSHAAEVMYEET
ADGGMQMKVKRKRPGTLGLCALIQNKYNIDAVPHVLCSGFTREETEDFLIELHYLGIDNV
LAVRGDDAAFKKPLKFGRSMNDYAVDLVKQIAGLNQGKYIEDGLLDAEPMNVCVGVGGYP
EKHFEAPNLKTDIKHTKAKVDAGASYIVTQMFYSNKFYFDYLKQCRIEGISVPIIPGLKV
ITSKAQIRSIPKNFFIDIPQELADEVEAAKPEHVIEVGVEWTKKQVEELLNENVPSVHFY
VMQNSKPIKLLMNKLKL
>A0A7X8F0T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MKISDILKKKKLLVSFETFPPKPSADESTYKSIVDATLELSSLNPDFMSVTYGAGGGTSS
NTVDIAAKINNEGSVPALAHLTCISSTREQVAIAVQKLKESGIKNILALRGDIPQNSDFI
PPNHYKYAYDLIKELKETTDFCIGAACNPEGHPESTNKDVDLDNLKKKADLGCSFLTTQM
FFDNNMLYNFLYRAQLKGITQPVFAGIMPVTNAAQIKRMMALSNAFMPRELLHLIEKFGS
SNEAMKQAGIDYATHQIIDLISNDVRGIHIYTMNKPDVARSIMNNISSIVSSQNDSTE
>A0A828YV02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira weilii str. 2006001853|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPDGDLKLMETVKELALLDPDFVTVTYGAGGSTRDK
TVQILSEISKRYSFPTVSHFTCVGANQDQIFKALEEIRSSEIVNLMALRGDPPKGEGKFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPDAKSLEEDVENLKRKVDAGTDFLVS
QLFFVNSIFENFLNLVRKAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A1F5YPD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Glassbacteria bacterium RIFCSPLOWO2_12_FULL_58_11|TrEMBL
MSLPAFKDALRDSILVCDGAMGTQIYSHGVHLSRSFDEVNLSNPYLVSKIHHDYISAGAR
VIETNTFGANRLKLRRHALADKIGEIIAAGVKLAREAAPRDEVYVAGSAGPLGVKLNHPE
GIEKDEAREVFAEHFTLLLDNGVDLLFLETFSDPLELALALETARGLRPDFPVVASAVFD
ERGLSQGKTPEQVVGLLEPFQPTAVGLNCRLSADLMLPILQRMHAATRLPLSAMSDAGES
RLVEDRDMYISTPEFVADYARRAIQGAGVRLVGGCCGTNPRHIRAIAATVRMLQPGTPSI
SVKEAEAGPPRFEKEGKPWKEKTPFAAKLARGKFVSSVEIRPPRGLDSSSVKEALEGLAA
AGVDAMNIPDGPRATARMNPIHIASRLNTEPERIEIIVHYTCRDRNLLGIQADLLGAYSL
GLRNILAVTGDPPKLGDYPDATAVFDVDAIGLVGILNRLNHGEDLAARPIGDQTEFLIGV
GVNPGAINLDLEVERLMAKIENGAEYVFTQPVFDPEFLTRFLDRAGKLPVPLLAGCYPLY
SYKNAEFLHNEVPGMTIPEEVRLRMKEAGTGARAQDMGVEIAREALREVRQRVQGAYIMP
PFDKWELAVRVLDGIIEPAPVSKK
>A0A6C2TYS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontiella desulfatans|TrEMBL
MKRLKDSLADSSSFTVIAELTSGAGCSMEPIFAFLEAHKASGGSEIPDGFDFAGIALPQN
PGGVSNLDPSDVLAQLAPTDLLDNLDFIPHMSCKDHNKAALNSALVGYRQRGVQSVLALT
GDKPVSSKGVFELEAVGLLQLVSETNRNELLKGSHADPARARPFFAGAAVSPFKYTEPSQ
MQQYFKLEKKVASGARYFISQVGWDWKKSRELKCYMEDVGLNVPVLGNAYFLTTTNAAPR
LMNTGKLPGCFVSNALLAQLQSENLDGHIDRCAQQVAMYKTMGYAGIDLGGVHDHATFIR
ILRRAAEVGDGWVEFRDNLCWPPEQAFYLYNEEGIRTTLAPGKPTLHDRCFDFMHSALLD
PGHKGFHAFRKMLGKGNPNGLACKSVFAMERAIKHAAFDCEECGDCHLFENFGYCTMGGC
AKGLANAPCGDANVDGTCGNEEGLVCRGEQIYRAAKAHPGGLDRLRKTINNPRNPSLEHT
SSILNYLFGRDHTMKNAIITIGEDIHASIPKHGAVMRELHALGEGAYENASPQLDYMRAL
VENQATEGADYIAINVDDFGDTDPALAAKIMVEYVKLVRQWGKGVPACIDSSDDNVLIAG
LKAWYNTTDPVKPPLVNSIKTYTADHMMPLRKEYGFSFIGMLIDEDSANAGTAQSVEDLV
GLAKEIFGKAMQAGFKPDEIFFDTTVFPLAIDMPMMPGVAGYTYRAFETIKAIKADPGMK
GVHFSMGVSNCCRDLPGRKIGICRAYVEKAMECGLDAGIVNAAHKYGTTPADPKLVELVS
AYAAMDGDMDKTNDAVELMGEFCDSLRK
>A0A845L6D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heliomicrobium undosum|TrEMBL
MTRITVELVPRSEEALISELEMIQQEFPQVMGINIPDLLRFPLRSWDACTCAKRYFETAI
PHIRAIDLNPDMPLQMAEQLQQDGITEVLIVTGDPPQDMSRKVYPTTSIDVIRRFKRELP
GMKVYAAIDPYRYSLRKEYDYIKRKIDAGADGFFTQPFFDLRFMEIYGEMLEGQQVFWGI
SPVTTEKSACYWETKNHVVFPAGFEPTLEWNIRFAREVLDFVEQSKANMYFMPIRTDLRA
YLHGIFCNS
>A0A4R4IGM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. ATCM1_4|TrEMBL
MTAISFEFYPPKTDDQRAQLDRTAAKLKGHAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFQAAPHLSCVGGTREEIRELLKLYRAIGVKRLVALRGDLPSGMGFPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQANDALADLRHFKTKIDAGADAAITQYFYNADAYFHFVDA
VTRLGVDVPIIPGVMPISNFSQLRRFSEQCGAEIPRWISKRMQAYGDDAESVRAFGADVV
ASLCERLIAGGAPSLHFYTLNLAKPTNAVLQRLDRG
>Y0KEA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilaceae bacterium 11|TrEMBL
MNQPVAYSFEFFPPKTAEGIANLREARKSLAQFKPEFFSVTFGAGGSTRDRTMDTVFEIQ
DEGYAAAPHISCISSSKEEIRELLSAYQAKGIKRLVALRGDVPSGEVSAGDFRYANELVA
FIRQETGDWFHIEVAAYPEFHPEAQSAAKDIANFKRKVEAGADSAITQYFYNADAYFRFL
EACEQAHIDVPIVPGIMPIYNYTQLARFSGVCGAEIPRWLRLRLEAYGDDMASLRAYGAD
VVTEMCDKLITSGVKNMHFYTLNQAGTISKIIQNLHG
>A0A0Q5QC49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. Leaf180|TrEMBL
MKITDHIKNANGKALFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGYTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTPGGHSSAMDLVNQINNLGRGKYLHDEQICDDHNKFCIGVAGY
PEKHMEAPSLNNDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVTKARELGITVPIIPGIK
PIATKKHLKLLPQVFKIDLPEDLINAVESAKNNEAVKQIGVEWAISQCRELMDFGVPVLH
FYSMGKSDNIKKVAAELF
>A0A353PWF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MKISKIIDKKKLLISFEIFPPKQEANFDSVMQTALDLGGLNPDFISVTYGAGGTTRSYTA
ELASSLQEKTQIPSLAHLTCVGSGFSDIQSIIRELKEKKIENVLALRGDYPQGADASDLP
GDCAYASDLVRILKKEADFCIGGACYPEGHPESENRLEDLQHLQYKVDAGLDFLTTQMFF
DNEVLYSFLYRMQSKGMKLPVFAGIMPVTNAKQIKRMITLSNAHMPQKLLAFVDRFQDNP
GAMMQAGIAYATEQ
>A0A1H2A0Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Friedmanniella luteola|TrEMBL
MRTGCPKRMVHGPCGGVRPDGRCEVAEHPCVFLDLPEPPPVTPVAGTPPAAVPEVLTDLS
VPPSDRATLTRTARRLAGSADALLVGDHQDRPDFSPSLLARLIAEAGVRPWVTLACRERP
RAALEAELDRLRADGLATVVCVTGDGRRPEVATAAPAVFDLDGTRLAGLAAARGLPVAVP
EAPAAPPRGLRPQRLVRKQQAGAAVAVLNHVGRPEAVAAFVAAARTRGLTMPVVAAVAVF
TDERSAAALAALPGLELDRAAVAAVLARPDPVEAGIRVAVAEARALLAVEGVAGVNLSGL
ASGRGTAFAADVQAEIGTRIRDGRAVRG
>U2DAN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] symbiosum ATCC 14940|TrEMBL
MKIKDILAAGSPTLSFEVFPPKGEEAYESVEKAALEIAKLKPAFMSVTYGAGGGTSRYTV
GIASDIQRETGVNTLAHLTCVSSTRSEVKSVLKQLREKQIENVLALRGDIPADGPIATDY
RYASELIYDIKQFDENLCIGAACYPEGHVESVNKTADIEHLREKVEAGCDFVTTQMFFDN
NILYNYLYRIRERGITVPVVAGIMPVTNVKQIKRICQMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAKIGNSLSEIL
>A0A352B9M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MIDNALFASRPAFSFEVFPPKKDDGIEKVYDTLDELSDLHPDFISVTYGAGGSENCGKTL
DIAKRIKNVCHVESVIHLPCLHLTKQEAEKMLLEFSDNGIDNLLILRGDKIEGREPSGDF
FHASDLIKFIQEKMPGRFHLLGACYPENHPDSKNVFDEIANLKIKVEAGAGHLLSQLFFD
NDQFFRFTENCRFAGISVPIEAGIMPVTNKLQIERMTSRCGVELPQKYKIMMEKYGSNDN
AILEAGITYASNQIVELLSSNVDGIHLYTMNKPYIARRLAEVVEPLILRKKQ
>A0A368A3J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Tokpelaia sp. JSC188|TrEMBL
MPVCGLLHHGDVGDFINVSFEFFPPRTEQMEKNLWQTVNRLSPLHPHFVSVTYGAGGSTR
KYTMRTVARILKETELPVAAHLTCVNATCSEVDQVARSFAALGIRRFVALRGDPINTSGS
IYNATPGGYANAVELVAGLKSINSDFDITVSAYPEKHPESLDFAMDIDLLRRKIDNGATR
AITQAFFDNDLYERYMDKLYAAGIDIPVLPGILPIHSFRHISNFCNRNGTHIPDWLARRF
EGLDNDPKTHALVSAVVAAEQVLDLVERGVKDFHFYTLNHADLSYAVCHLIGIRPKNDRN
SSL
>A0A0J8QMZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coccidioides immitis RMSCC 3703|TrEMBL
MHVKEKLAHSEASGRPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPAFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDWALQCAHKAGCTNILALRGDPPREKES
WAPTEGGFRYAKDLVKYIREKYGNHFDIGVAGYPEGCEDEEDPETLMKHLKEKVDAGGTF
IITQMFYDVDIFLDWVKRCRENGIQVPILPGIMPISTYASFLRRSNWVKCKVPESWMEAL
EPVKNDDAAVKQIGKKLVANMCQKILDSGIRHCTTPLQKPLPWRQSLGLGRRDEDVRPIF
WRHRHQSYVLNIKLWGEPKSIKDLSAIFIRFLEGGLDRLPWSESPITEETDDIKHDLIDL
NNRGFLTINSQPAVNGMSSSHPVYGWGPKNGYVYQKAYLELLIPPEVIGEVIRRIEKNPD
LTYYAINKNGELKTNTSDSPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAFRLGDDWAK
CHDARSPSRQLIQRVMDEWYLVNIVNNDFHKTHDIFNLFNDIVVKDLDVEATGIEESTSQ
PANTNPERQNGDAAQTKDILVGTNGTSN
>A0A0D7CS59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces natalensis ATCC 27448|TrEMBL
MRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSVTYGAGGTSREGTVRA
TERIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALRGDPPGDPMGEWIKHP
EGVGYAAELVQLIKESGDFCVGVAAFPEMHPRSTDWDADVRHFVDKCRAGADFAITQMFF
YAEDYFRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELADRIMAVKDDP
AAVRSIGIEYATELCASLMAEDIPGLHFITLNHSTATLEIYENLGLHQRS
>A0A352TB28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MTIAEILNSRKVSLSFEVFPPKKKEALDSIKETACSLTKLHPDFISVTFGAGGTTKGYTA
EIAEAIEKNGTTALAHFTCVRLTKEALNYSIQNLKEKNIKNVLALRGDFPKDTVTGENVF
PSGCMHASDLVSILKDEGMCVGGACYPEGHPESPSRDADIDLLKYKVDAGVDFLTTQMFF
DNDMLYSFLYRLQSAGIHVPVLAGIMPITNANQVSRMVDLSNAYIPRKLLAICDRFRNSP
EAMMQAGIAYATDQIIDLISNGVRGIHIYTMNKPEIAKAIIQNVDSIIKATNYSCSSQGM
PNM
>A0A625WGA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enteritidis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAKADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8I1ZTV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdus sp|TrEMBL
MSTQSNLERVLKSGTFAVTSECGPPRGADPEVVKKKGSYLLGYVDCVNVTDNQTSVVRMS
SFSACLVLKGVGLDPIMQMVCRDRNRIAMQSDILGAAALGINNLLCLSGDHQKFGDHPTA
KNVFDIDSIQLIQTVKGMRDEGRFISGQEVKGKPNIFIGCVENPFADPFEIRALRLAKKA
AAGAQFVQTQCVFNVEKFEKWMEMVRDLGIHEKIHILAGITPMKSIGMAQYMKNSVPGMD
VPEEQIERLKGVPKEKVTEEGIKIAVETIERVRAIKGVAGVHIMAIEWEEKVQEIVKAAG
LHPRP
>A0A1J5IGC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacteraceae bacterium CG2_30_61_12|TrEMBL
MAASFKDTLKSGEFIVTAEVGPPKGTDIGEMKQHIELLKDKVHGINMTDNQSSVMRLSSL
VGCHIIKELGGVPILQMTGRDRNRMALQSDLISAAVLGIDTVLCLTGDHMTLGDHKDAKP
VHDLESVQILKAVRTLESGKDLGGNPLKGAPSFCAGAVVTPEADPIAPQLLKFEKKIRAG
AEFFQTQAVYDLDNFKRFMDYAAKFEVKILAGIVLLVSAGMAKFMNKNVAGIFVPDALVR
EMESVPKKEQLQKGIEIAGRMIRTLKEQSIGHGVHIMAIGKEAVIPEILQVAGLL
>A0A7S3RM16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strombidinopsis acuminata|TrEMBL
MKLRQGESLPVLRRGAALEPGWFSFEYFPPRTDEGVENLRKRIVRMKNLNPMFTDFTWGA
GGSTSELTLTLTSAAKNEYGCVANMHLTCTNQKAEMVGDALTKCKELGVRNIVALRGDPP
RGSEKWEATEGGFSCALDLVKYMRKEHGDYFAISVAGYPEGHPDNIKVVEGGVAELTPSE
ARRARVVKDKDGKEVVTVCRDAEWKIEMQYMKEKADAGADFIITQMFLDAGVYAEFVKDC
KAWGINIPVVPGIMCLNTLGGFYRMTELCKTRLPPGFAEKCEAANTSDDAFKKWGVEACI
QMCKECLAAGAPGLHFYTLNLEKVVVGTLLGLGMITEAQAASCRSGDADAKTMVSAQGIV
TGEKARPKLSGNRPLSEADPTMHALVAEEKARQMRSIELIASENYTSRAVMECLGSALTN
KYSEGQPGARYYGGNEVIDKVENLCKDRALKAFGLSDKEWGVNVQPYSGSPANFAVYTAL
LPPHARVMGLD
>A0A846TP92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesobacillus selenatarsenatis|TrEMBL
MSFLKRLENEILIADGAIGTLLHAYGAGTCYEELNVSHPDDIIQIHKAYINAGADLIQTN
TYAANYIKLERYGLEDQVKEINSAAVKLARQAAGTDAYVLGTIGGNRGIRPSAIPIEEIK
RSFREQLYCLLLEGVDGLLLETFYDMEEIETVLEIARKETNLPIIAQVSLQEIGIMQDQT
PLQEAFHRLEDLGADLVGLNCRLGPHHMISSLEQIELPSKAFLSAYPNAGLPAYTDGKFH
YEGDPEYFGKSAHSFRNQGVRLIGGCCGTTPEHIRAFADELKGSAPVLNKQIPEKKPKII
VTPTDIKRPVAPLHQVVQERPSVIVELDSPRKLDTTRFFEGARALKDTGIDAITLADNSL
ASPRISNAAIGQLVKEKVGLRPLVHLTCRDRNIIGLQSHLMGLHTLGLHDVLAVTGDPAR
VGDFPGASSVFDVSSFELIEMITQFNEGLSYSGKDLGQKGVFSIGAAFNPNVRSIDKAVL
RMEKKIRAGAHYFISQPVYSEKMLLDVHEAMKHIDAPIFIGLMPLTSSRNAEFLHNEVPG
IKISQEVRDIMAKFNNEPLQSKREGIAITKGLIEAAAELFNGIYIITPFMNFEMSVELSS
YANEYSSLLKRRKQNVNVVN
>A0A7S3W033|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strombidinopsis acuminata|TrEMBL
MPYADDKKISDLIATTKPGWFSFEYFPPRTDEGVENLRKRIVRMKNLNPMFTDFTWGAGG
STSELTLTLTSAAKNEYGCVANMHLTCTNQKAEMVGDALTKCKELGVRNIVALRGDPPRG
SEKWEATEGGFSCALDLVKYMRKEHGDYFAISVAGYPEGHPDNIKVVEGGVAELTPSEAR
RARVVKDKDGKEVVTVCRDAEWKIEMQYMKEKADAGADFIITQMFLDAGVYAEFVKDCKA
WGINIPVVPGIMCLNTLGGFYRMTELCKTRLPPGFAEKCEAANTSDDAFKKWGVEACIQM
CKECLAAGAPGLHFYTLNLEKVVVGTLLGLGMITEAQAASCRSGDADAKTMVSAQGIVTG
EKARPKLSGNRPLSEADPTMHALVAEEKARQMRSIELIASENYTSRAVMECLGSALTNKY
SEGQPGARYYGGNEVIDKVENLCKDRALKAFGLSDKEWGVNVQPYSGSPANFAVYTALLP
PHARVMGLD
>A0A6P2RX77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MKTIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSVITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVV
>A0A1Q7IQV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium 13_1_40CM_4_67_11|TrEMBL
MPHAFDRRLAAGPLLCDGAMGTLLYARGVSIDACFDVLNVSQAKVVQSVHSEYIAAGADC
IETNTFGANRFKLAVHGLASDVHQINLRGVKLARDVRESMGRDVLVLGSVGPLGKYLAPL
GTVTADEARAAFREQAEALLEGGIDAFVVETFSDLTEIALAIETIRTLTDLPIVAQMAFT
DEGVTFAGRSPAEVARTLRELGVRALGANCSVGSSTLYEVLEAMGPEARDVPLAIQPNAG
LPHRIGERLMYLSSPGYMADYAGRMIDAGARIVGGCCGTTPQHIAAMRRVLDARAPASKA
EPRPTSAARVIEALETPGLRTTLAPTLLGRKLEQRSFVVSVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLPTAILVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALGIRNILAMTGDPPRTGDYVNATAVFDVDGIGLLEVLRRMNEGMDATGNGIGEPTSFCV
GAALDPGAPDPGREVERFHRKLEAGARWFQTQPVYDLEVLDRFLARVVGSPVPVLVGVLP
LHSFRHAEFLHNEVPGITIPDGVRARLRAAGDGALRAGIDMAQQLVGEIRSRYAGAYLMP
SFGRFEVVAEVLDVLR
>H0UDL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus laterosporus GI-9|TrEMBL
MGKRDLRAYLTQHVLVGDGAMATQLYEQGVPIGVSYEELCLSNPQIIRNVHTAYYEAGAR
LIETNTFGANRDSLSRYGLESKVTRMNRAAVTLAREAVGDDAFVVGAMGSIIAGRVRTKQ
IDQFKDQFEEQATSLLHAGVDGILLETFLDVDELLLALEVIRPLTELPIIAQLATLEVGT
TRDGHSLTYAFQQIKDAGADVIGLNCRLGPAEILRSFEATVCPDDVFLSAFPNAGRLGMA
DGTLSYKSSPDYFAESALRLHEQGVRLIGGCCGTTPEHTRAIAEKLAGRKPLPRVNPPAP
IHSERIEVQAVQKRLQPSIIEEVKHHPTIIVEFDPPKDLHTEDFLQGCCALHDAGANAIT
LADNSLATVRMSNMALGAMMKRLGIEPLLHIACRDRNLIGQQSHLMGLHALGIDQVLVIT
GDPSRFGDLPGASSVYDVSSFDLIRMVKQLNQGYAFSGKQLKQHAQFIVGAAFNPHVRHL
DAAVARLEKKVEAGADYIMTQPVYDAETIVQIYEATKHIRVPIFIGIMPLTSSRNAEFLH
NEVPGIKLSPYALEQMKLFTGEAARQEGNRMAKELIDATLQYFNGIYLITPFNYYQMTVE
LTQYIRQQEQVKAGLKEVSSS
>A0A0Q5U514|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. Leaf194|TrEMBL
MKITEHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFDPPFIDVTSLREDYIYKE
QDNGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTREETENALIDLQFLGIDN
VLALRGDARAADSAFIPTKGGHCYATDLIEHIKNHNDGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNTDFRFLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLSQLNVLPKIFHIDLPEDLTDALSHAKSNAEAKEIGTEAMIKQCKELMDFGVPVLHF
YTMGKPEQTKRIAKAIF
>A0A1F4F8V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_67_28|TrEMBL
MSVESGTRPAAAAIATHAAELLACGSIEMGAHQPEMAQRIAALLPSGTPVYVNHLPRHSL
ADALASLIAVREAGLEPVPHLAARRIASRSELETFLRRAVGGAGVRKVLLIGGDESTPLG
PYADGAAPIRSGILTGCGVREVGIAGYPEGHPRIPAAALEKSLLEKLALAAAEGLGAFVV
TQFSFAPARVVEYCAGLARRAPGVPLYVGLAGPSSLATLLRFAQRCGVSASLRALRAQGF
GAVQLVTHTDPGEQLATIARYCTVHANCNVVGAHVFSFGGAAETAAWMNRFIASRAAH
>A0A5E3XNW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peniophora sp. CBMAI 1063|TrEMBL
MKLADKLASADKPFYTFEFFPPRTDQGFSNLLPRIGRLAQLKPQAVAITWGAGGSTKDRS
LDLASLTQREYGIDTVLHLTCTNMQQGLVDDVLRAAKALGVQNIMALRGDPPRGEEYWMP
ADPRFKRARDLVSYIRSTPEFADHFSIGVAGYPDGHTDSVVNTMSEEEEIKYLKEKVDAG
ADYIVTQLFYDVDNFLRWLKRIRDAGITVPVIPGIMPLQTYASFQRLTKLTGAHIPAELH
AQLEPIKTDDQKVKDSGVSLAISMIKRLNESSDVRGFHFCTLNLEKSVQRILDALGWSSG
ASRAQNKLITEHDGARGDPQKPFLLVTPAEAATSLQDSKAPKGELGKGEVVNASAWDEFP
NGRFGDVASPAFGNSNQWGGYSFSNHNRNVWGAPRSLEDITNIFLAFLKGDINAFAFSPV
PLSSETALILPHLTKLAERGMWPVGSQPAIDGARSDDETVGWGPSGGYVYQKAFVEFFCT
DDMADALEKKVAEHGHGVVDLLMAQAEGGEEEGHGFVERLQGDRNAVTWGVFPAQEIVQS
TMIESESFLSWKDEAFATWSAWAALFPPDAPERTLLERVRRKRWLVNVTHHDYKDADALW
RFLLDD
>A0A2E2FFB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVTEHIEKAAGKTLFSFEILPPLKGMNIDCIYDTIDPLMEFNPPFVDVTYHREEFVYKD
RGNGLLEKKSTRKRPGTVGICAAIMHKYGVDAVPHIICGGFTKEETENALIDLDFLGIDN
VLVLRGDPIKTETYFKPEVGGHEYAIDLLKQVADLNQAKYLDEDIKNXTNTXFCIGIAGY
PEKHFEAPNLKSDLHWLKKKVEAGAEYIVTQMFFDNSKFFDFVNRCREEGINVPIIPGLK
PLSTVKQLNLLPHRFHIDIPEELSDEVLKASSNDAVRQIGIEWCSQQSKELMXAGVPVXH
YXSMGKSDNIQTIASKLF
>A0A0F4KVW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium asteroides|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLMPDFISVTYGTGRRSDRTATARIAKTIH
TEYGIPAVAHLTAQYADREVIDQALDMFDDAGVAAVLALRGDSVEGREPAGVFDHASDLA
AYIRSRRPNLSIYGACYPETHPEAASPEEDIENLKIKVDSGVDHLVSQLFYDNADFLDFL
DRARAAGIQVPIEAGIMPITNEGQVRHMSEVCKARIPAAVESILERWGDDRASLREAGII
YASQQIADLVAHGVDGIHLYSMNHSGVTRRIWHNVRHLFHQAGAKEEAADPKL
>A0A3E1L8K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris|TrEMBL
MSPDPPSRAATITDAYSLEVSAHDMPALTAAAPQIMRGSSMFIPYLLNQNDEARLAAAQR
VRALGFAPMPHLSARRIASLDALQAFVRRAVDEAGVERCLVIAGDAPSAVGPFSDSVSLI
ETGVFERSGIKTIGVAGHPEGHLGMPASAQWDVLERKCRSIAERGMAPLIVTQFAFDADT
VLTWLEALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACASMLSKYGISLGQLFGTA
GPDRFVDHLATGLSEAHGGVSLHFYPFGGIAQCVAWVEQYRRRSARPLAD
>A0A0U4XYB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas oryzihabitans|TrEMBL
MKPSLSFEFFPCKTEAGHEKLIATARQLAGYGPEFFSCTYGAGGSTRDGTYRTVRQLNDE
VGVPTAPHLSCVGDSKAKLRELLQQYREAGINRIVALRGDLPSGMGLSGGGELRYASDLV
AFIREETGDHFHIEVAAYPETHPQARSFTDDVRNFVYKMEAGADRAVTQYFFNADCYFHF
VERVRKLGVESPVIPGIMPITNYSKLARFSDACGAELPRWLRKQLEAYGDDTQSIQAFGE
EVMTALCERLLEGGAPGVHFYTLNQAEPCIAIWRNLGF
>H1HLL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella maculosa OT 289|TrEMBL
MKVIDIIQQHKDRRGLSFEVLPPLKGNGTDGLFATIDKLRELEPLFINITTHHSEYVYKE
LPNGQFERNRVRRRPGTVAIAAALQNRYRLPVVPHVICSGATAEDIEYELLDLQFLGIEN
LLLLRGDKAKDDRVFTPTPGGYAHTTELMHQVNRFNEGFFNDDTPIKHPGTPFAYGVAAY
PEKHEEAPNLEMDMQYLKMKQEMGAQYAVTQLFYDNGKFFDFVSRARQAGITIPIIPGIK
PLARLSQLTVVPRTFRCDLPEALANEVVKCKSDEDARRLGIAWGIDQCRELYASGFHTIH
FYTVSAVDSVKEIAREIL
>A0A6I2SXT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
MRIIDTIRPGKPFISLEFFPPKERSDWPAFFRTAERLALLQPLFVSVTYGAGGTTYGNTL
EIVTRIRQEIGLETMAHLTCIGSYRGEVLQFLDELERVGVDNVLALRGDLPQGAPPEYSA
CRTLLNASDLVAFIRSSHPHFGIGVAGYPETHPEAESPEADLDFLRLKLDQGGDFVVTQL
FFDNRLYFDFVRRARELGVDKPIIPGIIPVFSLKMIRRIVSLCGATIPAAYMEELEEADR
TGGPEAVQQVGVAFARRQAQELLDAGVPGIHFYTLNRDEAVTELVNALVF
>A0A7G1KSY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia wallacei|TrEMBL
MGQLARRPDGTIPFSVEFNPPRDAAAEARLWRAAREFERMHPAFVSMTYGAGGSTRDRTA
RVTGQLARETTLLTVAHLTAVEHSVAELRSIVGTYADAGIRNLLVLRGDPPGDPLGEWRK
HPDGLEYAEDLVRMVRGLGDFHVGVASFPQGHHRSPDLDHDTAYLCAKLRAGAEYSITQM
FFDVDHYLRLRDRVVACDAVEGAKPIIPELMPITSLRTVQRAEELSGRPVPAALMRRLER
AAGNDPEANRNDVRAVGIEIATEIGQRLIDEGAPCLHFITLNFAKATTEVLTNLGYTVTA
APVSA
>A0A7V6W7R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKQTNQHQLIQRLNEVTCPILMDGAMGTYFHKLTGQPADACEESNLQAPELITSIHRSYL
EVGSRVLRTNTYAWLDYLSRYDREQTDTMIRAAYGAARLALAEFKAEQKSVAQTATVPDT
DTDMFFILADLGFLPDTFGEEVFGEFKHTIDTWMDLGATHFICETLRDDRYLLDVACYIK
EKLPETCVMASFAIPPDGITAAGEPIDILFSRLDEMPELDILGLNCVSGPVPTTRLLSRI
GPLKKKLSVCPNAGYPTVIDRQMVFPTSPAYFGEQMRSILRLGANLVGGCCGTTPFHIKE
LAKVVADDCVTAGKRSMSQRVATEVTTKESSIESEAGQSVVPVVKTADEIPVVTAVETGE
ESPSAHAHNPILQRMTQGQRLIAVEYDSPATPDIQPYYDGALAIEEAGADALTIADCPVA
RPRGDSSLTAAALKQVLTHCEPIPHLTCRDRNANATKAILLGLNMLEIFNVLIVTGDPIP
QEDRDDIKGVFNFNSVVLGEYIRTLNETLFAKPFNVAGAFNINALKLEYELERARRKIEV
GVKTLFTQPVMSERGVERMAQMREELPEAYIMGGIMPIVSHRNALYMQNELSGMYIDDDI
VARYEGKNRDQGEAVALDITVRLAEQISPYIDGFYLITPFNRVDLICRILSEIKNL
>A0A6J0NEA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raphanus sativus|TrEMBL
MKVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTA
DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK
FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYLK
KKVDAGADLIVTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCKTK
IPAEVMAALEPIQDNEEAVKAYGIHLGTEMCKKILAHGIKSLHLYTLNMEKSALAILMNL
GMIEESKISRSLPWRRPANVFRIKEDVRPIFWANRPKSYISRTKAWEDFPQGRWGDSRSA
SYGALTDHQFSRPRARDKKLQQEWVVPLKSVEDIYEKFKELCLGNLKSSPWSELDGLHPE
TKIINEQLAKINTKGFLTINSQPSVNAERSDSSTVGWGGPGGYVYQKAYLEFFCSKDKLD
EVVEICKAMPSITYIAMNKGESWVSNTSQSDVNAVTWGVFPAKEIIQPTIVDPSSFNVWK
DEAFETWSRNWANLYPEADPSRNLLEEVKNSYYLVSLVENDYINGNIFKVFADL
>A0A3N9VH68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp|TrEMBL
MRIIDRILPGKQFLSLEFFPPKNTSDWPAFFRVVDKLRALQPLFVSVTYGAGGSTSDNTL
AMVTRMKQEFSLEPMAHLTCVGANEKNILDFIDHLAAAGVDNILALRGDPPQDPGVVLPE
SKDFIFASDLVSFVRKHYPSLGIGVAGYPEGHPEAVSLEKDVQFLKNKVDLGGDFVVTQL
FFDNDYYWDFVQRARESGNEKPIIPGVMPIFSLKVIQKVVQLCGATIPAQLLRELEEADE
QGGADAVLALGIRHARSQILGLLKGGVPGVHLYTLNRDDACLELLDGIF
>B6QPH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)|TrEMBL
MHVGQKLQEQAATGRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRS
ELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALEAAYNAGCTNILALRGDPPREQEK
WEAAEGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSTF
IVTQMFYDVDNFLNWVEKCRAKGINAAIVPGIMPISTYDAFMRRSNWTKIRIPPDWLEKL
EPVKADDAKVREVGTKLVAEMCRKLLASGHIHHLHFYTMNLAQATRLILEELRLLPSEEA
PLQKPLPWRRSLGLRRRSEDVRPIFWRNRNASYIARTADWDEYPNGRWTDARSPAFGELN
AYGVRLKGTNEQNIKLWGAPKSIKDLSDIFLRYLNGKLERLPWSDSSVTLETSDIQNELL
DLNKRGFLTINSQPAVNGVKSTDPVHGWGPRNGFVYQKAYLELLVPPEHVEELLRRIEKN
PDLTYYCINKTGELRARSDEGPNAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQLGDDW
AKCHPADSPSRKLLQRVMDEWYILNIVNNDFHKNDDIFRLFDGLVIKDFETEVPGTAPEV
ADGTSTN
>A0A0Q9JL33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces sp. Soil535|TrEMBL
MAETGQDAGGADCRPRPPVSFELFPPRTDAAALALGRTIDRLAEARPAFISVTFGAGGSS
RDRSLTVLRYMLEHTDVEPMAHLTCVGSSHAEANRLVREFLDAGITSFLALRGDPPAGAD
PDAGIGDLDSAAELVQLIHRVQEEREPFAQVGIPGLPGVTQIRDRPRPERVAVAAFPTGH
PRSRGPAQDVDTLLAKEIAGANLAITQLFWHADDYFGFVERARAGGVTIPILPGIMPVTT
PARLARVTELTGVEPPAELAIDLEIEPDPEAQTELGIVYAARLAADVLDGGAPGLHLYTF
NRHETVLDVLDRLGIGANDRLVNERNTTER
>A0A2I2KVS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia canadensis|TrEMBL
MTAVPTVSAKPTTMAEFLASGVPSFSFEFFPPRTADGERQLWTALRQIEALRPSFVSVTY
GAGGSTRDGTIRVTERIATETTLTPIAHLTAVNHSVAELRQVIGNYAGAGVRNVLALRGD
PPGDPQGEWAAHPRGLSYADELVRLVRSVGDFCVGVAAFPDKHPRSADLDADARHLVGKF
DAGADYAITQFFFGADDYFRLVDRVRALGCDKPIIPGIMPVTNVAQIVRMAQLSGAAFPP
ALAARLEAVADDPAAVRAIGVEVAAELSRSLLDGGAPGLHFITLNRSSATREIFQAVR
>A0A5A7VZ54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. T12-5|TrEMBL
MPAISFEFFPPKTDEQRAQLDRAAQALKAHRPEYASVTFGAGGSTLSYTGDTVARLHTQH
GLSVAPHLSCMGGTRAEIAELLDGYRAAGYRRIVALRGDMPSGMATAGDFRYAAELVSFI
REHCGDHFHIEVAAYPETHPQADDALRDLQHFKAKVDAGANGAITQYFFNPDAYFRFVED
VRRLGVNVPIVPGIMPIANYSQLKRFSDMCGAEIPRWIAKRMQAHGDDADSVRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRTRATQAVLQQLF
>A0A4U8SNY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. MIT 03-1616|TrEMBL
MYDIESLIEQLHSTEPFLSVEIAPSISGRLDENLLEDLKTLKLAHAFVCTDSPLARFKPS
SILSSLKFQNALQKPVICTISMRDRNSIALCGDILSVNELGLRTFLTLTGDSIKNGDCLQ
SKGVFEDNSLKLGHIIDELNCGRALNGKSLKENIKRIYNFQVINAYANNPLSLKNKMRKK
LSSCEIHALFTQPVYSLNAAEFLLQNLEEIKSECNIKSALVLGFFPVLSYKTALFLRDKL
PGVYIPNEWVQKLEKAHNKGKDEENKVGLEISHSLFMELKSVHNKFHFMSANKPSLVKEF
A
>A0A2X2X1M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium jejuense|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINNLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A368KCV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter denitrificans|TrEMBL
MPSISFEFFPPKTDEQRTQLDRAAQVLKAHQPEYASVTFGAGGSTLSYTGDTVARLHAQH
GLDVAPHLSCMGGTRAEIAALLDNYRAAGYRRLVALRGDMPSGMATAGDFRYAAELVGFI
REHCGDHFHIEVAAYPETHPQADDALRDLQHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VRKLGVNVPIVPGIMPIANYSQLKRFSDLCGAEIPRWIAKRMQAHGDDADSVRALGAEVV
SQLCRRLLDGGAPGLHFYTLNRARATQAVLQQLS
>A0A410MSC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sphaericus|TrEMBL
MGLLEKLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESSVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLDDI
LATVEEQASVLLAGNPDGLLLETYYDFEELTATLNVLRAKTNIPIIAQVSMHEPGVLQNG
MSLNNALHELEILGADIVGVNCRLGPYHTIQAFEAVELPAKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVSEKHAKPEKIEI
VRDAEPAKFEPLHEKVKRERSVIVELDTPRHLEIDGFLEGAKQLYEAGADVVMMADNSLA
SPRISNIAMGALLKSTNGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDVLAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKIIEIYEATKHLQAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSEDALSRMKACGEDKERATLEGIAIAKELVEVAAQYFQGIYLITPFLRYDVTLELMKY
IEQLDEQKKGVSING
>A0A2S5CU20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sphaericus|TrEMBL
MGLLEKLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADVIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLEEI
LLTVEEQANVLLAGNPDGLLLETYYDFEELSATLKMLRGKTELPIIAQVSMHEPGVLQNG
MTLNQALHELQALGADVVGVNCRLGPHHTIQAFEGVEIPDKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVALRDQGVRLIGGCCGTTPKHIAAAKKYLEELTPVEAKYTKPEKVEI
VREAEPATYEPLHEKVKRERSVIVELDTPRHLEIDGFIQGAKKLYDAGADVVMMADNSLA
SPRISNVAMGALLKETHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDVLAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKIVEIYEATKHLDAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSDDALSRMKACGEDKERSTLEGIAIAKELVEVAAEYFNGIYLITPFLRYDMTLELMKF
IGQLDEQKKGVSIDG
>A0A497RJC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon|TrEMBL
MSKLSKNFGKEFIVTGEVAPPRGPDLKEFMHEVEEFKKLMNRLYGVNVVDIPGAKLLMSS
LAASILLKQNGIDPIYQLVCRDRNQLALEADLIGAAAFGIENVLALTGDHPSCRSSDHPK
AKGVFDLDSATLIKTMKLMNQGKDLVGVDLNKPTNFFIGAALAPGATPIEGEIHKTKRKL
DAGTDFFQTQAVFESSMMWDFLDKYESLMKEDIADKILMGLVPLYSYGMVQFLRTMPGIV
ISEETGKRIKEADDPVEEGINIASELIDMAREMNLAGVHIMPSGKIEALMRLLESI
>A0A497RZX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon|TrEMBL
MSKLSENLEKKFIITCEIAPPRGPDLKNFMEEIHEIKKFMSKIYGINVVDNPGSMLLMSS
LAASILLMQNGIEPIFQLTCRDRNVLALESDLISASAFGIENVLALTGDHPRCMSSDHKF
ARPVFELDSVKLIKLIRQMNQGKDAGGKDLNKPTNFFIGAALAPSAFSKEAEALKTKKKL
DAGANFFQTQAVFYMPLVEEFLNIYEKVFKEDIRKMVLLGVVPFHSYEILEYLLMIPGVH
IPDSVKQRMKNAQDEMEVGIEIALELIDEARDLGLGGAHVMPAGKMTVLKKFLEEF
>A0A3Q7GLC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solanum lycopersicum|TrEMBL
MKVIEKIQESVKDDRVVFSFEFFPPKTEDGVDNLFERMERMVSHNPSFCDITWGAGGSTA
DLTLEISNRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGLATLETYENELAYLK
QKVVDAGADLVVTQLFYDTDNFLKFVSDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
RIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKIMASGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRLLPWRRPTNVFRIKEDVRPIFWANRPKSYISRTIGWDEFPHGRWGNAKN
PSYGALSDYQFMRARSRDKKLQEEWAIALNSVEDIYERFMYYCLGKLRSCPWSELDGLQA
ETKIIDDHLGNINSKGFLTINSQPSVNGAKSDAPLVGWGGPGGYVYQKAYLEFFCSREKL
NAVIEKCTAYPFLTYMAVNKKGNWMSNFNQIDVNAVTWGVFPSKEIVQPTVVDPASFMVW
KDEAFEIWSRGWAQLYPENDPSRTLLEQVQNSYFLVSLVDNDYINGDLFAIFKDIWN
>A0A1G3CTR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. GWA2_45_21|TrEMBL
MELSVEFFPPKTPEGETKLHLVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
AETGDWFHIDVAAYPETHPQAKSPATDVDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YDLGVTEPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDTASIRAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLSLNK
>A0A2M7C4V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG03_land_8_20_14_0_80_50_18|TrEMBL
MRIAEKLEASERGVSFECFPPKTEKGRSNLYGALGALEKYKPLFVSVTYGAGGGNRDTAV
DTVLSLKKDFTFEVMPHLTCIGAPASEIDGVLDTYKDAGIENILALRGDPPSALEGFDES
RGVFAHASDLIKHIKNEYSFSAGAAFYPEGHFQSPSPADDITHLAGK
>A0A1V6H7T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin057|TrEMBL
MKIANILKQKKTLSFEVFPPKRETDIGNLKETIQDLATLNPDFMSVTYGALGTTTDNSAA
IAKFIKENTKSEPLAHITGIASTKADIINLCNELKKSDIKNVLTLRGDNPENTNNLQSDF
EHASDLAAFIYEQFGDYFSCAGACYPEKHPEAVSFEVDIDNLKKKQDTGMEFFTTQLFFD
NDVFYRFLIKARKAGITVPILPGIMPVTSYKQIDRIIQVSGVLIPIQLRNYFDKYRNDKQ
ALEEIGIIFTSYQILDLLTNDIDGLHLYSMNKSHFIKKLMANISYVTTGYFANK
>A0A0M9YR90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MMG1533|TrEMBL
MALGTASTRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASNTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLTYAAELVELIKASGDFCVGVAAFPAMHPRSADWDADVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDKVAAAGCETPVIPEVMPIASVKSLDRVPSLTNAAF
PPALKERILTAKDDPTAVRSIGIEYATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A0T9JIL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pseudotuberculosis|TrEMBL
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIATDYWNSGIRHIVALRGD
LPPNSGKPEMYACDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFD
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A672HBK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salarias fasciatus|TrEMBL
NLQTDDSSNSTSGGESSKESSRCSTPVLDADRSDRLRDKMRRRIESGDCWFSLEFFPPRT
ASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLT
CCNQTREVITGHLAKAKHLGLKNIMALRGDPMGTDWEEEEEGFNYAVDLVKHIRAEFDSY
FDICVAGYPTGHPEAESYEEDLLHLKEKVEAGADFVISQLFFRADTFLKFLDDCRRIGIS
CPILPGIFPIQGYQSLRQLVKLSKLEIPEEITEVIEPIKDNDAAIRNYGIHQAVEMCRVL
LDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWAS
RPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLQMWGEELMNEE
SVFEVFTSYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELDKVNRRGVLTINSQPNIN
GKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVSALLKVLKKYEPRVNYHIVNVHGLNLT
NAPELQPNAVTWGIFPGREIVQPTVVDPVSFVSWKDEAFALWIEQWAKLYEDESPSRMII
KYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELINDPVNPADSTAHSEDPLSQLQAHHLS
NVPISPVFKALTSKTALFMSPFP
>A0A673TXI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Suricata suricatta|TrEMBL
MTVEVPLPKRPGRGHIGDGASGLQLGCFPPSRPASLCNLTPAPRPAPLRRRSPGGHAAAA
GASSLSHPPKGGRNSVMVNEPRGDGGPTPRLEGSSSGSESSKDSSRCSTPGLDPECHDRL
REKMRRRMESGDKWFSLEFFPPRTAQGAANLISRFDRMGAGGPLFIDVTWHPAGDPGSDK
ETSSMVIASTAVNYCGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQW
EEEDGGFSYAADLVRHIRSEFGDYFDVCVAGADDQCALGTTGLDAHRVIRHRAGSDRGQA
CRGPLVCSVEWKRQDKGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVS
LCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRP
IFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMWGEE
LTSEESVFEVFACYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINS
QPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVK
GENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESP
SRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPGTEQETETL
>A0A1N6QBQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalispirochaeta americana|TrEMBL
MAIERVSDLLSRGKTLFSFEFFPPRTEKGWSRLFHSIGEDLLPLEPAYVSVTYGAGGSTR
EYTHRLVTRIQNEFNLTVVAHLTCVGSSRKEIAGILDQYRRAGVFNILALRGDPQEGTIP
SGRETEFSCAAELVSFIRDHMPEASIGVAGFPEGHPDTPNRLLEIEYLRRKVEAGADYIV
TQLFFDNRDYFDYVERLKLAGISLPVVPGIMPVTTRKGMQRMAELAAGARFPAPLLRAVE
RTHDDQGVNRVGTHWATAQVADLLNRDVPGVHLYTLNNSWSTIHICRNLGLESYRL
>A0A1K2IEW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flaviramulus basaltis|TrEMBL
MKVTDHIKKANGKTLFSFEIIPPQKGRNIQELYNNIDPLMEFNPPFIDVTTSREEYVYID
KGDGLLDRKVTRMRPGTVGICAAIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIHN
VMALRGDAMSHQKYFECTEGGHQYAVDLVSQIQNLNTGKYLHDVMEAEHKSEFCIGVAGY
PEKHMEAPSLNTDLKRLKAKVDAGADYVVTQMFFDNNKFFEFVDKAKAAGINVPIIPGIK
PIAVKRHLQLLPQVFKIDLPETLINEVEKCKDNKAVREVGIEWAIKQSEELKKAGVPVLH
YYSMGKSDNIKAIASQLF
>A0A257ZCA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 12-68-15|TrEMBL
MTSPIRASRETSRPPVRVSFEFFPPKTEEMERTLWASIDRLAPLGPSFVSVTYGAGGSTR
ERTHATVERIARETGLAPAAHLTCVAASRAEIDEVVRDYAQAGIRHIVALRGDPVTGVGT
AYEPHPQGYAHACDLVAGIRRLGDFEVSVSAYPEKHPESPSLDADIDYLKRKVDAGATRA
ITQFFFENDVYFRFLDKVRAAGIDIPILPGILPVTNFKQAANFAGRTGASVPAWLLKRFE
GLENDPETRKLIAAAVAAEQVTDLVDRGVGDIHFYTLNRADLVYAICHLLGLRPGAAETP
AQRLAG
>A0A4U0GND5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinimarinibacterium sp. CAU 1509|TrEMBL
MNNDQIQFSFELFPPRTPAGAEKLPAVVSALAAARPAFFSVTYGAGGSEQQGTYETVMQV
VESTGIEAAPHLTCVGSSRSGIAATLQRYRDGGIRRIVALRGDLPATATSTQAPGEFRYA
NELVSFIRELHGDHFSLEVAAYPEMHPQATGPDVDFDNFRRKVDAGANGAVTQYFYNADA
YFDFVDRCQQAQIAVPVVPGIMPITNHAQLTRFSAACGAEIPRWIRLRLERYQDDREALL
DFGLDVVTRLCRTLLENDAPGLHFYSLNQSEPTLRLWRNLDLPLPIAAP
>A0A022LKU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia sp. UCD-THP|TrEMBL
MDRIASSRTPRVPFSVEFYPPRDEAAEARLWRAASVFSELGAAFVSVTYGAGGSTRDRTV
KVVERVVRETDLVPIAHLTAVGHSVAELREMIQMYVDVGVSNILALRGDPPGDPLGDWTP
HPEGLHYAEELVRLIHEVGDLHVGVASFPEGHYRARDLDHDTEILLNKLRAGAEYSITQM
FWDVEHYLRLRDRLESADPEQAVKPVIPGLMPVTSLRQVRRMVELSGCALPDGLSGRLRT
AAGDGPDEDRAAVREVGIEFATELCERLIAEGVPCLHFNTLNFSRATHEVLANLSMVPSP
DVVASGA
>A0A0Q8BEM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp. Root565|TrEMBL
MSESNSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVTKVKAGADAAITQYFFNADAYF
DFVDRARAKGVNVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGVHFYTLNSSEAPLAIWKELTV
>A0A4U1AK19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila sp. IMCC35006|TrEMBL
MSTETHFNSESNLEKVLKSGQFAFTGELGPPRGTDVEEVKEKAKFLKGNVDAVNITDNQT
AVVRMSSWAASLILIQEGLEPNYQMVCRDRNRLAMQADILGGSALGIRNMLCLSGDHQQF
GDHPDAMGVFDIDSTQLIAMVKQMRDEGLFLNGNEIHQPPKMFIGAAANPFADPFEWRVH
RLAKKIEAGADFIQTQCIYNMPKFREFVRLANEEGLTEKVYILAGVTPMKSVGMARYMKT
KVPGMDVPDEIINRLKGVEKDKVAQEGINIACEQIEEFKEMKGVHGVHMMAIEWEHMVPE
IAEQAKVLPRPVFS
>A0A0R0BKZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas koreensis|TrEMBL
MTALSFEFYPPKTDDQRAQLERAVRKLKAFAPTHVSCTFGAGGSTLSYTSETVRHLRQGH
GLEAAPHLSCVGGTREEIRELLKLYRALGCTRIVTLRGDLPSGMGHAGDLRHAIDLVEFI
RAEHGDHFRIEVAAYPETHPQAECALSDLRHFRDKVAAGADAAITQYFYNADAYFRFVDD
VRALGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIVRRMVAYGDDAESIRAFGAEVV
AGLCQRLLDAGVPGLHFYTLNLAKPSSAVLSQLNLARG
>A0A2W1NDT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus xerothermodurans|TrEMBL
MELALREALRHNIIVGDGAMGTYLYQMGFPVGISYEELNLLQPDVIIDVHRRYYEAGARL
IETNTFSANREKLSKYGLEHDVEAINRAGVELARKAVGNDAYVIGAVGSIRAGRRKNFRT
AEIKDDFRQQIEILLDTQIDGLLLESFYDLEEMLLALQMIRKLSPLPVICQFATEGTGVT
HDGFTLHEAFLQLQHHGADVVGFNCRSGPNGLLRSLEKVAGVTGLPPYSVFPNAGIPDYV
DGRYTYAATPQYFAETAVKFADLGARIIGGCCGTTPEHVAAMAKALAGYVPDGGRLDRLP
QTAKSGPAAQTTDLVQPRTGHAAYTVRLTDALPAPKPGAGAAENVTDQPNIIDLVKQRHT
VIVELDPPRDLDIDRFMKGAAALKQAHVDALTMADNSLAVTRMSNLALGYLVKERTGLRP
LIHIACRDRNMIGTQSHMMGLHALGINHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMI
KQLNEGIAFSGKTLRKKANFIVGAAFNPNVKYLDKAVQRLERKIEAGADYIMTQPVYDSA
LIEKIYEATKHLSIPIFIGIMPLASGGNASYLHNEVPGIQLSEHVRRRMGDLKGEEGRAM
GVQIAKELLETAMKYFNGIYLMTPFLSFEMTAQLTQYVWEKSGRMISTCTH
>A0A8H3ZA08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Venturia inaequalis|TrEMBL
MGIPKPMRLLAFISLGIFFYVCFLMFSSPLELQVPGTGKIEKMTKDPNLEPTGEPPEPLR
RVVGSNYAPNNPNSERINATLLALVRNNELRDMLQSMRDLERTWNHKFNYPWLFLNDEPF
TEEFKTAIRGATKAEVKFELVPKDHWETPSWINDDLYQESVKVLKEQGVQYMDKKSYHNM
CRWNSGMFYKHPALLEMQYYWRVEPNVHFFCDVDYDVFRYMQDHNKTYGFTVNLYDNPES
VAGLWPSTQQFIADHPEYVHPNSAIKWLQDDTMRRENYVKANGYSTCHFWSNFEIGDMSF
WRSKAYEEYFQHLDRAGGFFYERWGDAPVHSIGLGLFEDQNKIHWFRDIGYQHIPFFNCP
NSPKCSGCVTGRFTDGEQWLNKDDCRPAWFKYVGMASTLNMEKITDKLAALPEDGTYFSL
EFFPPKTTAGFANLQARLERMSRALRPFFVNVTWGAGGSTATKSLELAELVQRQLGLTTC
LHLTCTNMNKSLIDSALERAKAIGVRNILALRGDPPRNEEYFNKEDLDKESTEFVWAVDL
VKYIRKQYGDYFCIGVAAYPEGHSDQSHPDDQNPKHDLPYLIEKTKAGADFLMTQLFFDV
KAYEEFEDMLRNDPSGVFKTIPIVPGLMPIQSYQILRRTTKLSHARLPPDILERLDVVKG
DDEAVKAVGVDIISEIIQELQARPHVGPRGFHFYTLNLEKAVSQIVERCHLIRDLSAMDD
DDDDDSALEISDDVPDSNGQQRRSRLSSVHSDPRNKVIADRPSGHLNPEYETMEKEAGLP
IEGATRATTLLISEGEGSLGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVSAPQALK
LWGYPVTIDDVSSIFRRHIAGDLEAIPWSEDGLNPETATIREELLKLNAKGWWSVASQPA
VNGIKSADEVFGWGPRNGFVFQKPFVEIFIPAADWTGLKRKFEAYPEEITFFAANVAGDF
ESTDTKSVNPVTWGTFPGKEIVTPTIIEAVSFRAWAEEAFSIWREWQHIYPPRSATAKLL
GGLGAGGAAEPFAVSAANALVYGLFAVVCAAAGAINNLIGLNFGLALGAIGYPLYGAGLY
TNSTGANTWFLLFGSALCGTSAGFFWAAEAAIIIGYPSPTDRAFYLAIWQTAKAAGPIIG
GSINLGLNANRKTAGSVSTSTYIVFIAIMCLGFPIAICLSPASKVWRRDGSRISVNRAAT
WVAEFKAVGKLFISRRILLLLPAFFISYFYNGFSSTWLTTYFTVRSRAFSSFLTNFAGIF
SSFLIAALLDNQKIYIKTRARVAFLTIVTILIGTWIWATILQKEFYDADAPPVFDWFTGG
FGKAYALVFFWQFGGQAFQQFLYWLVGQYTTDLSSASHHVGILRGMEALGQTVAWAMQSE
GNANYFMAPQAME
>A0A516QWK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. BD59S|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPDVVRERMDGHETKEAAIEEGVRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>D0SZI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii SH145|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHNVAGIVITPHMLRALAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVKT
KNELVPELAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDLCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A7W7YMN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecobacter dejongeii|TrEMBL
MHIADILAAQRPTLSFEFFPPKTAEASEALYQTIGELEAYKPSFVSVTYGAGGSTRELTH
DLVVRIKKTTSLDPVPHLTCVCHSEADIAAILERYAEAGVSNILALGGDPPRNLEGYDRK
KDAFQQAADLVRFIKKFNESGAHPDPRGFGIGVAGFPEGHPTTPNRVLEMEYLKAKVDAG
ADYICTQLFFDNHDFLDFRDRCRLSGIHIPIIAGIMPITSASGMRRMAELAAGARYPAKL
LRAIQRCGGDEEAVQRVGVHYATEQCRDLLENGVDGIHFYTLNKSQATREIYASLGIRDS
AAVRPA
>A0A163KX70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Absidia glauca|TrEMBL
MKVIDKIQKAEQEGRVYWSFEYFPPKTSQGVQNLYDRMERMQRMGPEFIDITWGAGGSSA
DLTTEIVSTAQSVYGLETMMHLTCTNMEVEKIDTALKAAKDCGCQNILALRGDPPKGQSD
WESVPNGFEHAVDLVRYIRQQYGDYFCIGVAGHPEGHSDCPSKEEDLLHLKEKVDAGADL
IVTQLFFDVDAFLDFVKRARAIGITCPILPGVFPIQNYTGLKRVISFSNNHVPQKIWDDL
EPLKEDDAAVKEYGVDLAIEFIRKFQQAGINGFHIYTFNLERSSRLILERLELVAPLEAV
KPLPWHPALTQKRAKENVRPIFWKNRTKSYLQRTEFWDEFPNGRWGDSRSPAFGELDGWG
VSLKYSTNQCQEMWGHPETVDDIAMVFAKYCKGKIAGIPWSAQPLEAETETIRQRLAAIN
LLGYLSINSQPAVNGVKSSHSTYGWGPKNGYVYQKAYLEFFVSPEKLDDLIEKIGKNPNV
TYYAVNKQGDLRANTQSDHPNAVTWGVFPGKEVVQPTIVESTAFMAWKDEAFELWNEWAR
IYDRKTRPAELILDISNRWYLINIVHNDFQDEGGIWRLFDLEIDGEISRKIRQNGADY
>A0A1G3P7X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium GWF1_31_7|TrEMBL
MKIKDIYNKNKHIISCEVFPPKNDDDILKLYNTINEIKEISPDFVSVTYGAGGSTRDKTV
EIASHVKNIIGIEVMAHLTCVNSTVSDIDKTLDELKSRNIENVLALRGDPPQGQENFTKT
LGGFGFASELTRHISANHCFSIGVAAYPEGHIEAKDLATDIENLKIKVDSGADFMVTQLF
FDNSYFYKFRELCAKKGINIPMIPGILPILNYNSVKRITSLCGTIIPAKLKELLEKNQDN
KEEIEKIGIDYAIKQISDLLDNEIDGIHLYTMNKSNETKAIFNAVKEKIMR
>A0A846C2Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO2F4|TrEMBL
MNKFRNAVKSGEFLITAEVAPPKGADPTHMIKMAETLKGRVHAVNITDGSRAVLRMSSLA
ASIILKNIGLEPIFQLACRDRNRIALQADLMGASALGIHNILALTGDPVKAGDHKDARSV
FDMESTRLLQMIAKLNQGMDWNEKALPDGPTDLFVGAAVDPQSPSWSGLKRRFERKLLAG
SQFFQSQLISDFDKLEKFMNQIAVDSNKPILAGIFLLKSAKNAAFLNKYVPGVDIPEHII
NRLANAEKPLQEGIKIAAEQVKMASNICHGVHLMAIKREDLIPQILDMAEISPIRD
>R7CXG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. CAG:462|TrEMBL
MKVIDLIKEHQKTAFSFEILPPLKGTGIERLYQTIDTLREFDPKYINITTHRSEYVYKDL
GGGLFQRSRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKARHESMFTPEVDGYAHAIELQQQINDFNRGVFVDGSPIKVTGTPFHYGVACYP
EKHEEAPNMESDIYWLKKKVEAGAEYAVTQLFYDNRKYFDFVERVRREGIDIPIIPGIKP
FAKLSQLNMIPKTFKVDLPEPLASEAVRCKTDEEAAALGVEWCVAQCRELIAAGVPSIHF
YTVSAVNSIREVAKQIF
>A0A0D6QZX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria cunninghamii|TrEMBL
MKVIEKIQNAEKEGKVVFSFEFFPPRTEEGVDNLFERMDRMVEHQPSFCDITWGAGGSTA
DLTLDIANKMQNMICVESMMHLTCTNMPVEKIDHALETIKANGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHIRLKYGDYFGVTVAGYPEAHPDMIASEGGATEESYKKDLAYLK
SKVDAGADLIITQLFYDTDIFLKFVNDCREIGIKCPIVPGIMPINNYKGFLRMTGFCKTK
IPSEITAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNLEKSALAILANL
GLIDMTKIKRPLPWRPPANVQRTKESVRPIFWANRPRSYIARTIGWEQYPHGRWGDARSP
AYGAANDYQFLRRRSRNKKIVEEWVVPLSSIKDVKEKFSNYCLGKLKSNPWSELDGLQPE
TVKINEKLAQLNLKGFLTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYVEFFCSPEKLN
AVVEKAKQIPFLTYIAVNKKGDTVSNVGPNDVNAVTWGVFPAKEVIQPTVVDPISFMVWK
DEAFQAWDNEWATLYPDEDSSKKILQEVQNSYYLVSLVDNDYIHGNIFSAFEEI
>A0A2N3K7D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. EAG2|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSEDWETDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>X5Q2A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSJC285A00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDEIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A5M9INX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas extremaustralis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYQQAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2V7TGE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MPITLRELLDDGKVHVLDGAMGTMLYSKGFFLNVCYDELNVKQPKLVKDVHEAYVRAGAE
IIETNTFGANPVKLGSYGLADDTEAINKAAAELARGAAAGHASVVGAIGPLGVRIEPFGP
TSREEAYAHFQRQARGLLAGGVDGFILETFSDLDEIHEALRAVRGVSDLPVIAQMTVGDD
GLTHYGTGPETFAKQLTVWGADAVGVNCSVGPAGVLEAVEKLVKATDRPISAVPNAGLPK
DVGDRKIYLASPEYMASYARRMIEAGARLVGGCCGTTPEHIKKIRDYVASVVPRHQPIVV
SRDVIAAPAGVEEVPLARRSAWGAKLARGELVTSVEIVPPKGVDATPMLEQSRALKAAGV
DAVNVPDGPRAQSRMGVLPSAILIQREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRN
ILIITGDPPKMGPYPEATAVFDIDSIGLTNLVYRLNHGLDPGNNPIGKPTEWAIGVGVNP
GAVDLDRELSRYAWKVDAGAEFAVTQPVFDPEQLEEFLKRAEQFKIPIVAGIWPLISLRN
AEFLANEVPGVSVPESVLARMRKAQEKGKEAALAEGVKIAREMFQRVKGMVQGVQVSAPF
GRVEVALEVFG
>A0A7X5WJR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
ETFADLSEIRQALAAVRDACDLPVVAQMTVREDGTTLYGTAVELIAQRLDEWGADVVGLN
CSVGPHGILGGVERMTPVTRRPIAAQPNAGLPREIDGRKMYMASPEYMAKYAQRLIRAGA
RFVGGCCGTTPEHIRRISDAVHAMSPGRIRTRMRVERVTAADEGAAEPRPLAERSRLGRK
LAAGELVTSVEIVPPRGIDPAKMLAGVRRLRAAGVDAVNVPDGPRAQMRMGVLATSMLIE
QAVGIEAVVHYTCRDRNLLGMLSDLLGAHAMGLRNLLLITGDPPKMGPYPDATAVFDIDS
IGLTNLVNRLNHGVDPGGNPIGEPTSFTIGVGVNPGAIDLDHELNRFYWKVEAGAEYAIT
QPVFDADQLLAFIAELERREIRIPIVAGIWPLVSVRNAEFLANEVPGITVPEPVLERMRR
AQEEGKERAVREGIAIAREMFDAVRDEVQGLQVSAPFGRVDLALEVFDAVDSVSTAPPET
DDPAVPARPVFTPPGALD
>A0A2V7GBG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYAKGFFLNVCYDELSVKQPRLVREVHEEYVRAGAEILETNTFGANPLKLASFGLA
DDTEKINRAGAELARGAAGARASVVGAIGPLGIRIEPFGPTSQGEAEALFARQARGLLAG
GVDGFILETFSDLSEIHAALRAVRSAGDLPVVCQMTIGSDGLTYYGTDPETFTKELTAWG
ADVIGVNCSVGPAGVLEAVERMVKVTDRPISGQPNAGLPRDVGDRKIYLASPEYMASYAR
RMIEAGARFVGGCCGSTPEHIKKIRDYVASVVPRQASVVVPRAQIQAPAGVTPAPLVAKS
RWGAKLARGELVTSVEIVPPKGVDPAPMLAQSRALKAAGVDAVNVPDGPRAQSRMGVLPS
AIMIEREVEIETVIHYCCRDRNLLGMLSDIIGAHAAGLRNILIITGDPPKMGPYPEATAV
FDIDSIGLTNLVYRLNQGLDPGNNPIGGATKWVIGVGVNPGAIDLDRELSRFAWKVDAGA
EFAVTQPVFDQRQLEAFLKRVEQFRIPIVAGIWPLVSLRNAEFLANEVPGVNVPDEVLQR
MRKATDRGKEAALAEGVAIAREMFARVKTTVQGVQVSAPFGKVDVALEVFKA
>A0A838U0D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MGPYPDATAVFDIDAIGLTNMVNKLNHGLDLGNNPIGRPTEFSIGVGVNPGAVNMEEEIR
RFEWKVEAGAEYAITQPVFDTAQLEKFLKMIEHVRIPIVAGIWPLVSFRNAEFLHNEVPG
VEVTADILERMRIASDTSKEHAREEGITIARESLLEVHDAIQGVQVSAPFGNVKYALQVF
DALDEFRG
>A0A8A7JII9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rimosus subsp. rimosus|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVQHPEGVLYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATQLCARLMAEGSPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A2E9MBM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MNRFLDALGAGPLLADGAMGSYIFELTGRLSEPNHVYESFSLDRPEVIRDVYLGYLRAGS
RCLTTNTFAANADCLAVDGLAERLVDLNRAAIDIAREAAEQYRAGEGGEEIFVLASVGPT
ADPDQDDASTFDAYQEQLAAISGADALLLETFRSLASLRQVLSTVAQIPNRPPIIAQMAV
QQDADGWSTSPSELVDAAVAGGAAVVGVNCCTPWDAETFVEQASQLAAVAEGRIRLSAMP
NAGGFQHIGNRYMTRVNPEFMGRWARTMTQRGVSLVGGCCEIHPRHVWEMNNYLAGWGTH
SAGVTVEGAPVKKPSDGRIKRDNGGFSRKIVDGEFAVSVEILPARGTAPKLLQRKIDFVG
GLAASGLADGLDITDGSRGIPLMPPGDFIHVVRERLGWQPGQDGLELMPHFTSRDLNTMG
LQARLVGYWANGIHNVILVTGDPPKMAPSYPPSTAVFDLTSVDLIRLVNNGLNAGVDFGG
QALGKHADPRTRFTIGTGFEPESLDLTAEMEKLTRKIEAGADYIMTQPAFAWEPLEVLSE
VRQSVPVLVGVLVLTSLDHALRMRQVPGVVVPEAVLDRFGQSDDRASQAQVGRDLAAEQI
RRIQSEEWAGVYLMSPASHDPVIDVLRAGLT
>A0A7S1FBX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noctiluca scintillans|TrEMBL
MATEQHRKDSMLNELMSARKDTWYSFEYFPPRTEEGVKNLYKRILRMKTLDPLFLDFTWG
AGGSTSDLTMQLCDKVKNEFGAVANMHLTCTNMEKDKVDVALADCKKFGICNLVALRGDP
PRGEDKWEATEGGFTCALDLVKYVRANHGDYFSIAVAGYPEGHPDAIEEVAGGLAALTEP
EKRRARVAKNEAGVEVVTVCREANFHKEMTYLKEKIDAGSQCVITQMFLDAEVYLDFVKI
CRDYGITVPIIPGIMCLNGLGGLQRMTALCKTRVPVGMMEAAEKANTSDEAFKAWGIEVG
AQMCQRCVDGGAPGLHFYTLNLEKVVLGVLAKMGLITTEQLAQCSAGEADAKHMVSAQGI
TVDKRPQLPGNRSLEEADPVMHGLLQEEKARQMRSIELIASENFTSRAVMECLGSILTNK
YSEGQPNARYYGGNEVIDKIENLCKDRALKAFELNEKEWGVNVQPYSGSPANFAVYTALL
APHSRVMGLGLPSGGHLTHGYYTAKKKISATSIYFESLPYGVHPETGIIEYEELRKQALI
FRPAMILCGASAYPRTIDFAKFRSIADEVGAILMADIAHISGLVATKQHPSPFEHCDVVT
TTTHKSLRGPRSGMIFFKYSDAIPDIKERIDMAVFPALQGGPHNHQIGGLAAQLVEVMTP
EFVEYSKAVVSNS
>A0A7C2Y2B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MVVKRRRLRYNYGAMGMTFLDRLNREVLLADGAMGTLLLARGIEPKALMEQNLTHPDLIR
QVHLDYIRAGAQLIETNTFLANRLRLAEYGLDSELEAINRAAVRIAREAVRMSGEEVFIA
GSVGPLGALVKPYGNLTLDDLSAAYVEQIAILVDEGVDVIIIETHPSLLEALEAVRAAKT
VSPTTPIIAQMTFLEDGKSKFGDDLRRSLEALAAADADVVGVNCSGPQMTYDIIYEFLTT
TDLPVSIMPNAGLPQFIGGRTIYLSSPEYLREYARRFVEAGANLLGGCCGTTPEHIRAMS
TVVRGQVPRRVRQRTAVFVEVKEEPTAAPSTVPLRGRFRERLGREFVVTVEVHPPWGLEY
RSPIERIRQLAHCGVDAVSVHDPPEARVSLSSLVFAYLVQTQAGVEAIWHLSCRDRTLAT
IHSELLGAAALGVRNILALTGEAASVGEWPRRPSAHDVSPTGVVKIIEGLNRGRTLTGND
IGSPTDFRVGVLVQVGAEDLDAELRKLEERVAAGAHFIVTTPVFDVERFEHFLKRCAGFG
LPILVGILPLKSARHAEFLHHEVPGITIPDAVRERLRRAQEDEAAEGMRIARELIAQLRP
HVAGVHLIPPSERWDALPEVLAACLPQEQRTDALGV
>A0A0C3CYB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hebeloma cylindrosporum h7|TrEMBL
MKLLDQISRHDASKPFYTFEFFPPRTDQGFENLASRISRLSALNPLAISVTWGAGGSTKD
RSLELAGLSQNNGLNTILHLTCTNMRMGLIDEVLKSAKDQGINNILALRGDPPRGEEEWI
ASDPRFTRAIDLVNYIRSIPEYSDWFCVGVAGYPDGHADDSVDEDTEIDRLKEKVNAGAD
FVITQLFYDVDHFLSWYKKVRQKGITVPVIPGIMPIQTYSSFARVTKLCGARVPESLAST
LADLSHDDQLVKDYGVQLATQMITRIHSEGGIRGFHFCTLNLEKSVQRILEALRWIWQPP
SSLEKNKLIDPPGTPARAARMDSNLLISPLNAANTATLGLSTISTTEGEAGRGELNNAAS
WDDFPNGRFGDFKSPAFGNQDPWGGSGISKNETLSQWGSPKRLEDLTQIFFDYLHSKITS
TPFSPTPLSPESLMILPHLENLTKKGWWTVGSQPAVNGASSTDDIVGWGPRAGYVFQKCF
VEFFCEEKDVNAISKRIADRGNGWVHFFACNNEVGAQGKCISNVPDDGRNAVTWGVFPGK
EIIQTTIIERESFLSWKEEAFSIWSEWASFYRPGSEEREILESVRDNRWLVNVVHHDYKD
SEALWTFLDE
>S2XJ12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. HGB0015|TrEMBL
MSRLLKALQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVEHIHRSYIEAGADVIQT
NTYGANFEKLQPFGLEHKVKAIHQAAVAIAKRAARPETFILGTVGGFRGVKQGELSLSAI
QYHTEIQVDTLIESGVDGLLFETYYDLTELIRVITQTRQNYDIPIIAQLTASNTNYLRDG
TEINDALQQIVAAGADVVGLNCHHGPHHMKHSFSHIALPDKAYLSCYPNASLLDLDQHTF
QYSDNAQYFGDTAQQLIQEGVRLIGGCCGTTPEHIRHIKSAVKGLKPIQNKKVIPIDKKR
ETLAQNQHQLNLADRVRQKPTIIVELDTPKHLDTTKFFNNVKALDEANIDAVTLADNSLA
TVRISNIAAASLIKQRFGIEPLVHITCRDRNLIGLQSHLLGLSLLGIHEILAITGDPSKI
GHLPGATNVYDVNSKGLTELALKFNKGINTDGDALKTTTQFNIAGGFDPHVRNINAAVRK
METKIESGMSYFITQPVFSKEKIIEIYEATKHLNVPIFIGVMPITSYNNALFLHNEVPGI
KMSEEILEQFKAVAGDKEATYQLSISLCKSLIDTVHTYFNGLYLITPFERVDYSLELAAY
SKSITQTHQEAIL
>A0A6G7LMV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella chilikensis|TrEMBL
MAFHHAQHAHSLNQSLSELNGDINVSFEFFPPSTPEMETLLWNSIQRLEPLNPKFVSVTY
GANSGVRDRTHSVIERIQQETELVAAPHLTLVDASDEELLELARHYWNSGIRNIVALRGD
LPEGSPKPTRFASDLVRLLRSVADFDISVAAYPEVHPDATNAQADLINLKRKIEAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVGNFNQLKRFAAMTNVSLPGWLHRQFE
GLDNDPGTRALVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A6G7PFS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. JB150|TrEMBL
MNPGPTAPAPGPTAAVRAAALTLLEDFSLEMTGKDVPHLEKARQLIPPGTRINVTFLGNE
DLQTRLAAARAVKRFGFLPVPHLSARRLGSRAELEEFLDGLRADGTGEHVLVVGGDPARP
HGPYEDALSVIRTGLLERYGVRHVGVSGYPEGHPAITDRVLWAALADKSEALAGKRLGGH
VVTQFGFDADRVLAWVAEVRERGIGLPVRIGVPGPAGVRRLMSYATRFGVGTSASIARKY
GFSLTNLMGTAGPDRFLRALAEGYDPDVHGEVKVHFYTFGGLGATSEWVARFRAEPAAGA
>A0A256Z425|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon ex4484_231|TrEMBL
MQRYGQPAILCLHKQSCSFLPDSTKSGDGSHLPDYLQRKDLNDNPIESPPQFFVGAGANP
NADPIEPELIKCAKKVQAGAQFFQTQVVFDLDIAKNFLKETNRYNVPVLIGIFPLRSYGV
AEYFDKNVPGVKVPEELLEALKKAKKTPDKKERKQKYNEINLNYFANFIKELKKTTSAAG
CHVMSVGYESIIPSLAEMVK
>A0A7X3UMN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MRFLDYFTGNQPVISFEIYPPQTQGGMRALKARVIPNLLKLNPSYMTVTYGAGGSTRAKT
LEIASLIQNEFGLTAACHLTCVGSSRTDIDDILKAIRTEGIRNIVALRGDPPRGEDTFVP
AKDGFAYGNELVAHIRSTEPKDDGFGLAVAGYPEKHLEAPDFDTDIANLKRKVESGGDII
ITQLFYNNDYFFRFVDRVRAANITAPVVPGLMPILAAGQIQRIASLCGSEIPEDLQDQLK
GAVDDEDKAMRIGIDQCIGQATELLEQGVPGIHFYVLNKSTHMRRIISALPL
>A0A4C2E8X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygosaccharomyces mellis|TrEMBL
MSIRELYESKDGPTLSLEFFPPKTETGKRNLLERMERMTALEPLFITVTWGAGGSTAEKT
LELASLAQKSLNLPVCMHLTCTNMDRNIIDDALIKCKAAGIHNILALRGDPPIGQDWSDL
EASQSEFKHAVDLVKYINYRFPHEFCVGVAAYPEGHCEGEAEGNEQNPWKDLPFLKEKIN
AGADFVITQLFYDVDKFLQFEQIFRKHISEDLPLIPGLMPINSYLLFNRAAKLSHASIPS
NILQRFSPEIQADDDAVKSIGVDILIEIIEKIHKVTQGRVKCFHFYTLNLEKAVAKIVAI
SPSLSNVLDGVEDENDEAATSEPEEQDKEGDIVLDDVNIKDPVDENRKRRRQSSTVSNLS
SDLTSNRVIIGQKNQNGVGAPTRKVVISISQGSGTLGRDATWDEFPNGRFGDTRSPAFGE
IDGYGPTLKVSNKKAYELWGHPKAIKDLQTIFIKYLEGSIDALPWCDLGLSPETALIQEE
LIQLNNRGFLTLASQPATNGSLSTDKIFGWGPAYGVVYQKAFVEMFVPKNVWENGNMKKS
IEQYGRAKLTYYANDSQGNFETNLEPNSSNVVTWGVFSDSQVVQSTIVSEESFKAWSDEA
FSIWMEWAKLFPRNTSTNSLLRRVHQEYCLVSIVHHDYINPDELWEIVLS
>A0A2V7FHX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
ETVAPPAGVEEVPLARRSRWGAKLAQGTLVTSVEIVPPKGVDPAPMLEQCRALKAAGVDA
VNVPDGPRAQSRMGVLPSAILIQREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRNIL
IITGDPPKMGPYPEATAVFDIDSIGLTNLVYRLNHGLDPGNNPIGAPTSWAIGVGVNPGA
VELDRELSRFHWKVDAGAEFAVTQPVFDVRQLESFLKRVEAYRIPIVAGIWPLISLRNAE
FLANEVPGVVVPAEVLERMRRAQEKGKEAALAEGVKIAREMFQQVKGSVQGVQVSAPFGR
VEVALEVFG
>A0A072NFH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter nitratireducens|TrEMBL
MQSQTQFKRRFSFEFFPPKTDQGKEKLQNVRNKLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRQEIGELLDLYKENGINRIVALRGDMPSGMGASGELRFAN
ELVEFIREHSGEHFNLEVAAYPEFHPQARNAEEDLQNFARKVKAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTNMCEKLLRAGAPGLHFYTLNQAQPSLSIWENLGISDREKIAF
>A0A4S5CPM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. LS-044|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLMPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLVDAGVPGLHFYTLNTAAATRTICERLDV
>A0A1G8IWU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio sp. 49|TrEMBL
MFKDMFERDSSLSFEVFPPKKDDEFENCYKVLDSLAEINPDFISVTYGAGGSRSKKNR
>A0A435HSY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.001.04.2.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQAPTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYIDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAEQSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>V6XW20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum E18|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A2S7Q2A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rutstroemia sp. NJR-2017a BBW|TrEMBL
MEKITAKIAALPPDTSYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRKLVDQALEDAKALGIRNILALRGDPPRTDE
YRAVDEKDGGSPAMDWDFEWAIDLVKYIRKQYGDYFCIGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVEAYDHFEKRLREHPSMMPIQSYQMIKRTTKLSHAKL
PTDIMTRLDTVKGDDEMVKKVGVDILSEIVEHIKVTKSQYSGPRGFHFYTLNLEKSVSFI
LERTNLIPEVTDDDSEALEAELLPPISHLTVNGSHKRSSRRHSSVGSDPHNRIIITAAQA
SNPSYEATALEAGVPAEAVNSRANTLAISEGEGSLGREATWDDFPNGRWGDARSPAYGEI
DGYGVSLHMSINQAIKLWGHPASTSDITNIFLRHIEGQLTAIPWSEEGLNEETNSIKKQL
LGLNKKGWWTVASQPAVNGVRSSDPIFGWGPKNGFVFQKAFVELFIPASDWKTLHSKLTS
PELCDTVSFYASNAKGDFVSSDQGGAGSTNAVTWGAFPGKEIITPTIIEEVSFRAWSEEA
FGIWGEWARVYGAKSETRKVIEGIMDDVWLVNVIHHAYVEKEGLWDLLLN
>B6QZS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudovibrio sp. JE062|TrEMBL
MEQQLWSSIKRLEPLSPSFVSVTYGAGGSTRERTHSTVSRIVNETALKPAAHLTCVDATK
EEVNEVIQAYWDAGVRHIVALRGDPAAGLGEAYHPHEGGYQSTADLVASIKTIGDFEVSV
SAYPEKHPESPSWDAELDVLKAKVDAGATRAITQFFFDNDHYFRYVDRVRAAGINIPIIP
GIVPVTSFKGISGFAKKTGASVPGWLAHRFDGLDDDPRTRELVAAAVAAEQVMSLADDGV
EDFHFYTMNKADLVYAICHMLGLRAKQDVKASVAA
>A0A4Q4J507|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium fuliginis (strain ATCC 27551)|TrEMBL
MTLSFPSVEEATRAWQAPLYADLTGDINVSFEFFPPKTEKMEEQLWSAIQTLTPLAPKFV
SVTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKAEIDGVADAYWEAGVRHIVA
LRGDPPEAGAKFEAHPDGYKGAAELVEGLVKRHPFEISVAAYPETHPDALSARGDIDNLK
RKLDAGATRAITQFFFEPDTFFRFRDTVAAAGIDADIIPGIMPVSNFAAVQRMSAMCNTD
VPGWMGKLFEGLDDLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPATLEKTA
>A0A7C5ZBD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MNLRERLESDAFIVTAEMGPPQSAGHGVIRKKAAHFTRVDGVNITDNQTGIVRLSSIAAA
RICLEEGLEPVIQVTCRDRNRIAIQSDLLGAAAMGIENILCLTGDYPTFGDHPEARPVYD
LDSIQLIALVSAMNEGTLLSGQKLKTATRYLIGGAANPFARPLDARILRLKKKISNGARF
IQTQPVFDLPAFHQWVERVRQEGLNEKAALLAGVMPVKSVRALTFMRDQVPGMRVHPDCI
SRMASAKDPEEEGVRMAVETINRLRETPGIRGIHLMPLLWESITPVILEKSNLARRTEP
>A0A7Z2T0P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio astriarenae|TrEMBL
MGYTHASHIDALNQNIAELSEDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVT
YGANSGERDRTHSIIKEIKSETGIIAAPHLTCIDASREELIQIADDYWHNGIESIVALRG
DIPPGGGKPDMYASDLVELLKNRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANR
AITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQF
EGLEDDATTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQP
>A0A6L4Y8N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKLREALAKGKFLVTTEIQAPIDEEPEGLVKTFNLVRGRVDGISVSEVEIEGIVGDTIKT
CEVLKQNRFEAIYQTSTRQKNRLQLQKDLTLAHEAGVENLLVFTEDYRITGDSLQEIMFF
HVDSGKLASVLEHMREGETVDGKELPFKAEFVLGSGVESSWGKNVPELEMKEMEEMTGIG
TGYFLTTPVFDLDRFEKFVKTVETFGVPVIAEVMILRTAGMGRFLNRHFKSGLVPEWIIQ
KLAKASDKQKASIYLFADIVTGLKDICQGIHIITIGGEEKLRYYLDAAKLR
>A0A7X6WZ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MKGGKTISLEFFPPREDAAREKLALAARELVARQPAYVSVTYGAGGSTRSGTADAVELMQ
SLGTDTAPHLSCIGSSRAELMEILDGYRAQGIRRIVALRGDLPSGMGRHPGEVHYADELV
SLIREHSADWFHIEVAAYPEVHPQASSASKDLDHFVGKVKAGANGAITQYFFNADSYFDF
VDRVRARGVDIPIVPGIMPITNYKQLARFSKMCGAEIPRWLEWRLVDFGDDRASLRAFGA
DFVAELSQRLLDQGAPGLHFYTLNNAEATLAVWDKLNVA
>A0A7C1PXJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKNYHHRFKNLITETNEFIITCEQIPGRVSRDRQLDEIITFAENSKESGLVHAISLTDSP
RGVPAILPDIIALEIEQVGMPAIVHFTAKDMNRNMSESRAFSLDRMGVHNLLVMSGDYQT
GGQSGLAMPVFDVDPVHIITMLSLINKGWRIKFNDHTLEEGPKTNFFIGSVVSPYKFTEA
DFITQMYKMEMKARAGSSYFITQFGFDTAKLKDLQQYMKVSDITIPVLGSVFVLRKGAAE
VIY
>A0A7C1BTC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MEKKFSEKLRDGKFVITCEIGPPKGTNLKFLQEAEILRDKVDAFNVTDLQSSVMRLGSLA
TCHLLVEKGLEPIFQITCRDRNRLALQSDLLSAYVLGIRNVLIITGDHTTLGDHPDAKPV
FDLDSVLLLKVASDLMDGKDMAGNKLDGKPEFFLGAVVNPGYEPIDLQIIKMEKKIEAGA
KFFQTQAVYDLKVFENFMKKVEKFKVPILGGIVLLKSAGMAKYMNENVAGVNVPERYIKM
LAEAPKSERPKVSIEIASELIKGMKDMCQGIHIMPLGWERYVPEVLEASGL
>A0A1Q5XCT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. P3E|TrEMBL
MKPDLRSAWKNNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYIEAGAVL
LESNTYSANYDKLSKFGLEAKVDEINRAGVRIARHAAGDTGYVVGAVGSIRAGKRANLSS
TELKRFYAQQFSALLEEQPDGIMLETFYDVEELHLALRAVRKLSELPVICQLAVDETART
LDGLTLTEAFHILEQDGADIIGFNCRTGPNGIKRALKSLQGSLRLPASVYPNAGIADYVD
GQYRYGASPDYFGQMAPVFADMGARIIGGCCGTTPQHIAEISAALREYSPQPLPEPTAQN
KLERLTVQEHLGDNEERDGHELTLVDLVKERHTVIVELDPPRDLDIAKFMRGAEALRRAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIKQLNDGIAFSGKPLKQNANFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIERIAKATAHLEIPIFIGIMPLASGR
NAEYLHNEVPGIQLSPEVRSRMQGLEGEEGRAEGVRIAKELLDAATRHFNGIYLMTPFMF
YDMSVQLLEYVWEKQGRKLSPLFR
>A0A522WCB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MTEKSKLQKELNAGKFVITAEICPPRGTDTSVFIEKARLLKGKITSANVTDNQRAVMRLS
SLACSALLLKEGVEPVFQMTCRDRNRLAIQSDILGAWALGVRNILALTGDHVSFGDHRDA
KAVYDLDSVQLVETIATLNAGKNMKGTELRGATDFFIGAVVAPEANPWEPEEMKFEKKVG
AGARFFQTQAIFDMDKFKRFFEGSVKFNVKVLGGILLLKSANMANFLNKNVPGVHVPPSV
IDELTGAKDQLEAGIKIAARQVRELKKFCHGAHIMAIGQEESVVKIIEEAG
>A0A6L4ZRA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MARQTLDFLSSLDKEVLLADGAKSTVWLEQGLSPANSVEQNLSNPENVIKLHLEYIEAGA
RIIETNTFRANRLQLARFGLSDEQRAINTAGVEIAKEAIKRSGQRNVFIAGSVGPLGALV
KPYGNITLAELGAIYQEQIQILYEAGIDILIIESHPSLLEALEAVRAARTLDTRPIIAQM
TFLEEGLSKFGDEPRRALETLAAADADVVGVNCAIGPHHMYNLLVDFLRSTNLRVSVQPN
AGQPQLISGRQIYLTAPDYLQEYAKLFVEAGVNIIGGCCGTTPEHIQAMAKVVTGQKPRH
STVQVSVQEQLAISSQTQMRNVLQEKLGREFVTTIEVDAPPGLNYRPHIEQVQQLISLGV
DAIQITDNPKARVRMSSIAFAHLVQIETGIEVVLHFTCRDRNLLAIQSELMGAAALGVRW
ILALTGDPSSVGELPAATSVFDVNSAGLVRILHGLNQGVTLAGTDISIPANFHIGASVNP
AAPNLETEIDKLKEKIDSGVDFAQTQPVFDLELLKRFADKTSHLNIPILVGLMPLRDPRH
AEFLHHEVPGTKIPDWIRKRLSSAKPSELLDESVAIASELLAGIKSCFPGVHILVNENTR
IVERLLAQ
>A0A7C2ND75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MNFIEILLIFLSMSNKMNKLLNENILFEVIPYPIKWDDYKKENFIKKVAEIIYKNNINVI
NVPEVVIENRNSNRNIAYLKKVPPLEFANYLNSYYYQNYKRKLDFIINVVVPIKEKDYFL
KYCENLVINGINKIVLVGKDRSDREYIGYEVLQASELLKKIYKDNLILGGITIFHRKNEY
LKIIQKKQTNIEFFISQIIFDKQNFYNLLNDLKNNSVSNLFNLKIYLSLATINSFKEFNF
MKFLEVYFPEDILLNISNITNDNDLRIFFNKIIDNLIVELSEIIFIFRKYNLDIGFNIEH
IMYDNLNFSEELLKKVKIKLKNIEFLKTKNF
>A0A6L9ETU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium R38|TrEMBL
MKVTEHIKQANGKTLFSFEILPPLKGQNIQSVFDGIDPLMEFNPPFIDVTYHREEYIYKE
LENGLLQKKVVRKRPGTVGICAAIQNKYNVDAVPHILCGGFTREDTENFLVDLDFLGIDN
VVALRGDAVKSETYFTPEKDGNQYATDLVKQIVCLNNGKYLDEDLENKAKTDFCVGVAGY
PEKHLEAPSLDSDIHFLKKKIEAGATYIVTQMFFDNQRFFNFVKKCRKAGITVPIVPGLK
PIATKKQLNLIPHRFNVDIPDDLIMEVVKCKDNKAVRQVGIEWCTAQSKELIAEGIPVLH
YYSMGKADNIKMIAKEIF
>A0A7V7H508|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. BF2-3|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7V7X1K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MSDNRPNNFLETLSERILICDGAMGTQLYDKGITFDHCFDAINISHPQLIRDIHSAYIDA
GADIIETNTFGGNRFRLTHHGFEDKLFDINRTAANLAREMADKKKKELGKDIFVAGSVGP
LGKPLEPIGKIKHEEARAYFTEQIQILADGGVDLIMIETISDIEEAKEAVTAARDVTSLP
IVAQMSFTEDGKTLMGNKPQEVVKILKSLGADVVGANCSVGPQVLLEVLEKMNGMDDTFF
SIQPNAGLPRYVGGRYIYLASPDYFGEYAKLMVAAGVHIIGGCCGTTPEHIRSIRNAVGI
QAPKKVDKKISVVEPEEVTVKSLNRKDTHHSSLIDKFKSGKFVISVELDPPRGLNYEKVI
EGAILCKKHNVDAINIADNPLAKAGMTPLAMASLINKSVHIETILHFSCRDRNLLAMQSE
LMSAHVMDIRTILGITGDPPIVGDYPNATGVFDVDSIGLIKLINNLNQGIDLAGKPIGSK
TNFFKACAVNPTPVDLAREHERIEQKMAGGADFAMTQVLYDLKPLEEYAKKFKGRIPVLL
GIMPLRNAKHAQFMHNEIPDITIPEKIRERMNKAGDRGQEEGVKIAKEFLKEARHLVEGV
YVMPPFNKFEMAFDLLEVL
>A0A1Q9AML7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium rhizosphaerae|TrEMBL
MTLPERLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPEEVYERAAIFEGWVDGINAVD
ASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGASAMGVSNILCLTGDG
VQAGDQPGAKPVFDLDCMSLLETIRTMRDQSKFLSGRKLSAPPEVFLGAAINPFAPPYDF
RPYRLAKKIAAGAQFVQSQYCFDVPMLKRYMDTVRALGLHEQCFILIGVGPMASARTARW
MRANVPGVHIPDTIIARLEGAADQRAEGKRICIDIINEVKEIPGIAGIHVMAYRQEEYVA
EIVHESGVLKGRRPWRREPAGDEDRLRERLDGLEHDAVERPTDRAAEAANVAPQR
>I4VXF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. 115|TrEMBL
MPSISFEFFPPKTDEQRAQLDRVAAALQPAAPEYVSVTFGAGGSTLSYTSDTVRGLHQQH
GFHVAPHLSCMGGSRAEIAALLDEYRAAGYRRIVALRGDLPSGMATAGDFRYAAELVRFI
REHSGDHFHVEVAAYPETHPQAEDALVDLRHFKAKIDAGANGAITQYFFNPDAYFRFVDD
AQRLGVKVPIVPGIMPITNYSQLKRFSDACGAEIPRWIAKRMQAHGDDAASIRALGAEVV
AQMCLRLLDGGAPGLHFYTLNRARATLAVLERLH
>A0A2N0TRQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salegentibacter salarius|TrEMBL
MKITEHIEKAKGRSLFSFEILPPLKGQNIQSIYDGIDPLMEFKPPFIDVTYHREEHVFNE
KENGLLEKRIVRKRPGTVGICAAIQSKYGVDAVPHILCGGFSKEDTENFLIDLDFLGIQN
VVALRGDAIKSETYFTPEPKGNKFAKDLVEQIMEMNKGNYQDEVIEKGHNTNFCVGVAGY
PEKHMEAPSLDKDICRLKEKIEAGAEYVVTQMFFDNSKYFEFVDKCRESGITVPIIPGLK
PLATKRQLSIIPHRFHVDMPEDLISEVEKCKDNKEVRQVGIEWGIQQSKELVKAGVPVLH
YYSMGKSTNIQKIAKAVF
>A0A1G0F686|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium RIFOXYB12_FULL_54_9|TrEMBL
MSHSPISFEFFPPQTNEGVEKLAVARAKLATLNPEFFSVTFGAGGSTRDRTLETIIQIKN
EGYQAAPHLSCIGSTRENIHAILQTYKDAGIRRIVALRGDLPSGMATAGEFQYANELVEF
IRKESGDHFHLEVAAYPEFHPQAKSAQDDVLNFKRKIDAGADSAITQYFYNPDSYFYFVD
KCQKLGITVPIVPGIMPVVRFSQLARFSDTCGAEIPRWMRRTMEGFGDDNEAVQAFGRDV
VTQMCEKLLAGGAPGLHFYTLNQAAPSMAIVDRLGLAQ
>L8K2T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fulvivirga imtechensis AK7|TrEMBL
MKITEHINNAKSTLFSFEILPPLKGENIENLYNHIDPLMEFKPPFIDVTYHREEFVYKKR
ENGLLEKRSIRKRPGTVGICAAIKNKYNVDTVPHIICGGFNKEETENALIDLNFLGIDNV
LLLQGDAIKTESVFVPEVGGHRYASELLGQVVGMNQGKYLDEDLLNANPTDFCIGVAGYP
EKHFAAPNLKLDMKYLKMKVDMGAEYIVTQMFFDNQKFFDFVKKCREMDINVPIIPGLKP
ITSKRQMNVLPRIFYIDLPEELSDAIEKCKDDKQVKQVGIDWSIKQSKELVEFGVPVLHY
YSMGKSDSVYRIAKELF
>A0A522QR52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MKIAEILATRRPAFSFEFFPPKSDEAMAVLLETVSMLRSLDPAFVSVTYGAGGSTRARTI
EITKTIKRALDIEAMAHLTCVGATAEELRSTLHDFQSAGIENVLALRGDPPQGEAAFSAV
EGGFAHGADLVRLAREGGAFCVGGACYPEKHIEAADAAGDLRYLRYKVEAGAQFLITQIF
FDNQRYFSFVERARRSGIDVPIIPGIMPITNVAQIERFTRLCGAIIPPRLMAELEARREE
PEAVIDLGVAYATLQCADLLARGVPAIHFYTLNKSPATRAVVSALSAARPWEPAKGRRYV
ENADSLIESAFSLPSSL
>A0A133SKX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera sp. MJR8396C|TrEMBL
MHTNELFTKKTVFSFEVFPPKRDTPIESVYPTLDELSKIRPDFISVTCGAGGQGSNRTTE
VATYIKNLGCETVAHMPCIYLTEEEALETLEELKARGIENILALRGDETPGRERSHRFEH
ASDLIAFIKEKEPEFNITGACYPEGHAEAKTVVADIRNLKTKVDAGASELISQMFFDNTV
FYRFRERCEIAGIKVPIEAGIMPVTNKRQIENMIAMCGATLPIKFQRAIAKYGDKPDAMY
DIGITYAIDQIADLLANGVDGIHVYTMNNPDIAKRISEAVKNLL
>I8W4L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei CL03T12C01|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEAQINDFNKGVFVDGSPIKITGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVEKVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A8F6L4Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WY228|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVDHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGPWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A497ERJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Verstraetearchaeota archaeon|TrEMBL
MITAKRKPISEILTMVEGHKNVLLLACDGCVGIYDVGGLKQAEALKLELELAFKSKGKEP
PNFTTATVLRQCDTEIVKDSIAEQMEKVDAVLSLACGIGVQTVAHVFPEIPVYPANNTTF
MAMEDKTEGMLREWCMACGNCVLHITGGICPIARCAKSLLNGPCGGFYQGKCEVDGRTRD
CAWVLIFNKLKERGKLNLFTAIRLPKDYRDVKNPREFKREELVIPEAKEAIKILEDVEVK
KRPAYSQLMKELSEGKFVVTGELEPVKTTDLTEVIEGAKLLRDYVVAINITDNPTAFAYL
NALVPSYMIQEKAGVEAVYQMVTRDRNRLALIADLLAAGALGIKNILALAG
>A0A844F2F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium scindens (strain JCM 10418 / VPI 12708)|TrEMBL
MKTTELFQNKSVLSFEVFPPKRTNPVDTIYKTIDSLKDLNPDFISVTYGAGGSENCKATL
EIASRIKNEYGIESVAHLPCISLTKSDVRRQLSDFKEAGIENILALRGDVPSCGYVPGDF
RHASDLIAFIKEHGDFNVLGACYPEGHQESADIFDDIKNLKTKVDAGASHLITQLFFDNH
YFYRFRERASLAGIQVPIEAGIMPVTNKKQIERMVSLCGVTLPHKFSAMMERYEHNPDAM
RDAGIAYAIDQIVDLITHGVDGIHLYTMNNPYIAARIYEAIHQLLAA
>A0A4Z2EJT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liparis tanakae|TrEMBL
MGAGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCDQSKEKITGYL
AKAKHLGLKNIMALRGDPVGADWEEEEEGFNYATDLVKHIRSEFEDYFDICVAGYPTGHP
EAESYEEDLRHLKEKVDAGADFIITQLFFRADTFLKFLDDCRAIGITCPILPGIFPIQGY
QSLRQLVKLSKLEIPEEITRVIEPIKDNDAAIRNYGVQQAVEMCRVLLDSGKVPGLHFYT
LNREVAIMEVLRQLGLWTEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQDWD
EFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLQMWGHELLSEESTF
>A0A845M9H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritimibacter harenae|TrEMBL
MSKFFEDPNAIRPYEPIPDGHVSGSLLERALRAGEFAVTSELNPPDSADPEDVFEAARPL
AEVTDAINATDASGANCHMSSIGICSLLTRTGHGTVYQISCRDRNRIAIQGDVLGAAAMG
VRNVLCLTGDGVGAGDQPGAKPVFDLDSVSLIRLIRTMRDTGQFLSGRKITKPPRLFIGA
AENPCVDPVDYRADRLAKKVEAGADFIQTNYIFDIPRFERFMERVRDMGLGKRVFILAGV
GPLASAKAARWMRSNVPGLHIPDSVIERLEKAEKPGDEGRKICVELIQQIREIPGVSGVH
IMAYRREHLVADILREAGIARMAKAG
>A0A7S9RRZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter concisus|TrEMBL
MLKEKILNKEKGLVLYGLTPPKAEFEEAKLREISERWTGRINDIKADGLVLYEVQDESER
NDSERTFEFSGTLSPEIYYKKYLNVATPSIFYRVASGYGEDEFRAALKAQSSNLNVLVGA
TSSTQKVRLNLARAYEIAGEFGDLAVGGVCIAERHGKKGDEPQRMREKIAAGAKFFISQA
IFDAQLARKFLEDCAAAKISEPIFLTFSTAGNAKTLEFIKWLGVSVPNSVEERLNFSSDY
LASSCEIIKEIWCKLKKFGDENGLNLSINIESVMAKRAEIEASLELTKSIRELV
>A0A6M1LAR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucosispora sioxanthis|TrEMBL
MALGLPSVLPNSQPAIGELVRDCQPTFSFEFMPPKTEQGERQLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLVVR
GDPPGDPTGEWIPHPDGVHYAEDLVRLVRHSGDFSVGVAAFPYRHPRSPDVDTDTDYFIR
KCRAGADFAITQMFFDADEYLRLRDRVAAAGCDTPILAGVMPVTRIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQTSEMCRRLLDEGVPGIHFITFNRSTATREIWQNLR
VGAAT
>A0A6N0KPY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. FDAARGOS_761|TrEMBL
MSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDRTLSTVLQL
DGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMASGELRYANE
LVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQYFFNADAYF
YFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSRSIQAF
GEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>F0SLW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MKSLSQIFASPHPVISIEIFPPKTEKGDRLLYETLDCLTQYQPAFVSCTYGAGGTTRTRT
IDLCLEIQRRYEIPATAHFTCVGSTRDELIEWLTAATANGVQNIMALRGDAPKGEDCFKA
VEGGLSYANELVELIRTLHPNMGIGVAAYPEKHLEAPDMDTDLANLKRKIDAGADASFSQ
LFFVNENFFRFRELYDAQQITIPLVAGIMPITSFDRIKKITAMCGAIFPEELASKLEAVK
DDEEAQLQIGVDHATQQCVELLDQGVAGIHFYALNRSDACKRILENLDLSSRMAAS
>A0A537IZ91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MGCDFRETHQHCQGCRARTGGFTLRLSDAANNHPIVTVELIPDRVIPAHLPILQGRVDAI
TIPALRNGEGDPSYPAGFRVTPQTRSLASAVIVRKTGAEAVPSLTCRDFRRSDLGLVPSL
FKKGLDNFLVVFGDLYPGHRIEDYDFRKTEDLIRGVLSVFDGPRPCIGAVTNQYAKDQER
ETARTLRKVDAGADYVVTNTAFDDRLVLDHVDKLRSQGLKAPIFVQVSIPSGLKNLQFVS
RKFDIPVPEKVIQTLTRNPFGGGIHIAAQAYTALRGEVSGIHFSYLHRSHNPIPAYVHLL
DAIETDGQLTVSIQAALRH
>A0A497N6R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MKGKFTPFSELMKKIAAGEFVYTGELEPHKTTDISETIEWARTLKATGKVTAANVTDNPS
STACISSLVAAYIIQRETGLETIYQLRTADRNRLALVSDVLGAGALGLKNILALTGDHTM
LGDNPQSKPVFDLDGTQLIAMIKQMVYEGKDPAGNEIANPPKINVGAAAQPGADPLEMEI
LKMERKVEAGAEFFQTQVVFDVEVALKFLDEASHLNVPILIGIFPPKNYGQAEYFSKYVP
GVTVPDQFLADLKKLSEISDKAERKRKINEYNVEYFSNFIREIKKKPVCKGCHIMAVGYP
EVIGPIVERVEKGA
>A0A562V965|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides zoogleoformans|TrEMBL
MRVIDLINSHEKTAFSFEILPPLKGTGIEKLYETIDILREFDPKYINITTHRSEYVYKDL
GNGLYRRNRLRRRPGTVAVAAAIQNRYNITMVPHILCSGFTREDTEYVLLDLQFLGITDL
LVLRGDKAKHESIFTPEGNGYHHAIELQEQINNFNKGIFVDGSEMKITQTPFSYGVACYP
EKHEEAPNIHTDIYWLKKKMEAGAEYAVTQLFYDNRKFFDFVERARLEGITIPIIPGIKP
LKKISQVSMIPKTFKVDLPEELTKEILKCRNDKEVQQVGVEWCVEQCKELIANGVPSLHF
YSVGATDSIKEVARQIY
>A0A5C6VJ17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibaculum oceani|TrEMBL
MKVIEHIKASKGKTLFSFEVLPPLKGDKIDNIFSAIDPLLEFDPKFINVTYHREEYVYKQ
KANNLLEKFAIRKRPGTVGISVAIFMKYKIDVVPHLICGGFSKDETEDALIELKFLGIDN
ILALRGDPIKTERTFVPTKDGHRYAVDLIKQIVDMNRGQFLHDEVYENAPTDFCVGCAGY
PEKHVESLSLGTDLKHLKQKVDAGAEYVVTQLFYDNKKYFDFVDRCRAEGINVPIIPGLK
PLGRKRHLSFIPKTFNVDFPDDLAEQLVKAKTDADIAAIGNDWCIQQSKELIKAGVPCLH
FYTMGNSQQVANIAKEVF
>Q08QG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stigmatella aurantiaca (strain DW4/3-1)|TrEMBL
MRKAIVFSSGGGVKSGRTIAAHLFQSRPPGTDYTGPVMKIRNRLNPSNPCFSFEFFPPKT
DEGTENLLKTVEELAPLEPGFVSVTYGAGGSTREKTLGLVTRIKQTTGIESMAHLTCVGH
TRDELREVLQQLEAAKLDNVLVLRGDPPRGQTTFAPTPGGFRYASELVEFIREEDFNFCV
GGACYPEGHVETESRDEDLQHLKAKVDAGLDFIITQLFFDNAFYFDFVERARRVGINVPI
VPGIMPITNVEQVQRFTRLCGATVPMRLGLQLDRVKDQPDAVVQLGVAHATVQCMELLSR
GVPGIHFYTLNKSPATRMILGALRSRS
>A0A0U1KY41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa ovata|TrEMBL
MKITEIFKKGKPVISFEFFPARTEELAEKFNKTIDELLELKPDFVTVTFGAGGSTKDGSY
ELVKKFKKEKKQELIAYLAAFALRKNEITTVLDHYKDLGIENIFSLRGDPPKNTPTDQVP
ADSFRYASELTAFIRQNYNFCLGVAGYPEGHIEAPSFDKDIENLKHKVDQGAEFIITQYF
YDNAYFLNFVERCRKSGITIPILPGIMSVYSIKMMEMLAVNCGANIPDKLRQGIAELPEG
DTKALINFGIKYAINQCEELIKEGVSGLHFYTMDRSESTVGVVKGLKDKGLLRI
>A0A353KEW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp|TrEMBL
MALGTPSTWTDHARTVRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTREGTVRATQQIAADSTLTPVAHLTAVDHSVAQLRNMVGQYADAGIRNILAVR
GDPPGDPMAEWVEHPEGVRYAADLVRLIKESGDFCVGVAAFPERHPRSADWDSDIRHFVD
KCRAGADYAITQMFFHPESYLRMRDRVVAAGCDTPVIPEVMPLTSVRQLERFPQLSNASL
PSALKDRILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A1Q3Z2P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp. 67-54|TrEMBL
MPSDQRPSRNTGGRQPFELSFEFFPPKTDVMEERFWESVHKLAPLNPRFVSVTYGAGGST
RERTLRMVSQVKAETGVDAAAHLTCVGASKADVDQVVHAYKTAGITRIVALRGDAPEGPG
KPFVPHPEGYRSAAELVAGIRRIGEFDISVAAYPEKHPQSPDWDVEIDNLKRKLDAGASR
AITQMFFDNQHYFELLERSAKTGIRAPIVPGIQPIHSFRQISSFAAKCGASIPDWLAERF
DGLDDDPETHALVASAVAAEQVLELVDAGITQFHFLTLNRSNLVLALARLLGVRPD
>U1YCV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes sp. EGD-AK7|TrEMBL
MSNKQTLSLEFFPPRDIAAQEKLVRTAKSLMGLNPAYVSMTFGAGGSTRAGTVDAVALLQ
KLGFDVAPHLSCIGTAPAQLGEMLDNYRDQGIRRIVALRGDLPSGMGGDAGELRYASDLV
SFIRENYGEHFHIEVAAYPEMHPQATGFSDDLGHFVNKVKAGAHGAITQYFFNPDSYFSF
VERAQAQGVTIPITPGIMPITNSSQLLRFSTMCGAEVPRWIRLRLADFGDDRASIRAFGI
DVVARLCQDLLDGGAPGIHMYTLNGADASMAILPNLTWR
>A0A2I9D2Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. Br-6|TrEMBL
MTFDAVRGRNSAGFVTQTPSIVDRIRSSEASKSGRIPFSVEFSPPRDEAAEARLWRAVRE
FERLGPAFVSMTYGAGGSTRDRTVRVTGQLADDTTLLPVAHLTAVGHSIDELRAMCGAYA
DRGISNILVLRGDPPGDPLGDWVKHPDGVEYAEELVRLVRDMGDFHVGVASFPEGHYRAP
DLDHDTKYLVQKLRAGAEYSITQMFFDVEDYLRLRDRVVAYDREQGEKPIIPEIMPITSL
RSARRSLELSGSSLPPALEERLTRAAGDGPDENRAAVREIGIEVATEMSERLIAEGAPCL
HFITLNFARATGEVLANLGMSASASV
>A0A7V9IMZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MASISFEFFPPRTPEGAAKLRNVRAELAALDPEYFSVTFGAGGSTREGTWNTVIEMHGEG
LPVAPHISCIGTTRASVQALLAGYRNQGIHRLVALRGDMPSGAAGGAGDFRYAGELVEFI
RAETGDWFHVEVAAYPEYHPQSRSPDDDLQRFIAKVNAGADSAITQYFYNFDAYARFVDE
VHARGCTVPIVAGVMPIVSFTQLARFSDACGAEIPRWIRRRLESFGDDRASIREFGLDVV
TDLCEQLLAVGAPGLHIYTLNQADASVELCKRLASV
>A0A7C6JS28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MHIKDLFSNQKPVVSVEVFPPKPESPLDTVISTIEAVKDLNPDFISVTYGAGGSSRAYTV
EIADMVKNQYGIETLAHLTCVGTGKDEIDDMLAQLRSKNIENILALRGDMPQDENTGKFD
YTYAKDLITYIRSDSSFCIGAACYPEGHIDCDSLDLDLKHLQQKVSSGADFLITQLFFDN
ELFYSFKERLDALGIHCPVSAGIMPVINKKQIERITNLCGATISPRLKKIMETYADKPEA
LKKAGVAYATEQIIDLLSSGVDGIHLYAMNRPEVAQKIFADIKDVRGSCEHEHQLQ
>A0A7K2Y030|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID1046|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSIAELRHVIGQFADAGIRNMLALRG
DPPGDPMAEWVSHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVEKAGCDTPIIPEVMPVVGIKQLDRLPQLSTAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A7C6KMJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MKSGSNLEKVLVHGDFAVTGELGPPQSNDREVIVKKAKAYKGYVDAVNITDNQTAIVRMS
SIAACAIVAGLGLDPVMQMTCRDRNRIAMQSDILGASALGIKNILCLTGDHQSFGNHPTS
KNVYDIDSIQLISMVKGMRDDKKFLNGEEMKSEPRMFIGAAANPFADPFEYRVVRLAKKV
AAGADFIQTQAVFDVPRFKRWMEMVRDRGLHERVYILAGVIPVKSAGAMRYMKNDVPGMS
VPDELVRRMEQASDPKEEGIRICVETILQLREIEGVSGIHLMPIMWESVAPIIVERAGLL
PRPEY
>A0A540W9U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora acidiphila|TrEMBL
MALGVSSTRTDHAATVRDLLAAGRRSFSFEFMPPRSEAAEQKLWSAIRRLEPLNPNFVCV
TYGAGGSTRGRTVNMVGRIAGETTLTPVAHLTAVDHSVAELRNIIGQYADQGVRNVLAVR
GDPPGDPMGEWVTHPQGVTYAYELVELIKGIGDFCVGVAASPNMHPRSTDWDEDIRHFVA
KVRAGADYAITQMFFEVEDYLRLRDRVQAAGCEVPIIPEIMPVTNAKQLVRFPQLSGSEF
PPELAARLEAVKDDPKALREVGMEHATAMSEQLLSEGAPGLHFITLNGSTATLQIYQNLG
LHSS
>A0A269XID3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus pasteuri|TrEMBL
MSQFLKKLQNNVLVADGAIGTIFYSEGLDTCPEAYNLTHPEKVEHIHRSYIEAGADVIQT
NTYGANFEKLKAFGLEHKVKEIHKAAVQIAKKAANEDTFILGTVGGFRGVKQDDLSLSSI
QYHTEHQIDTLVDEGVDALLFETYYDLEELKGIVISTKRKHHIPIIAQLTASNTNYLVDG
TPINDALKQLVECGADIVGLNCHHGPHHMQRSFSHIELPDKAFLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIRYIKTSVKNLRPVTHKNVIPINKKV
NRKKDLNFKQSLTSKVKQGPTVIVELDTPKHLDTDQFFNNIGKLDDADIDAVTLADNSLA
TVRVSNIAAASIIKQRFNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEATKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITTHKEAIL
>A0A1H2PT90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinasiproducens palmae|TrEMBL
MELSFEFFPPKSADGIEKLRATRARLMPLKPRFVSVTFGAGGSTQQGTLDTVIEIARSGV
EAAPHLSCIGASAASIAAILGQFRENGIRRIVALRGDLPSGMVEIGEFPYASDLVRFIRR
ETGDWFHIEVAAYPEYHPQARSPRDDLDNLVRKFEAGADSAITQYFFNADAYFRLRDDAS
RRGIAAPIVPGIMPITNYAQLSRFSAMCGAEVPRWIGRRLESFGDDRESIRAFGLDVVSA
MCERLLAEGVPGLHFYTLNGAAATEAVCRRLGLGAA
>A0A5E4SGP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea communis|TrEMBL
MSGSLDNKTIMTQPSFSFEFFPPKTADGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQG
TLDTVIEIQREGVEAAPHLSCVGSTKENIRQILETYRANGIRHIVALRGDMPSGMGEIGE
FRYASELVEFIRAETGEWFHIEVAAYPEYHPQAKSPRLDLEHFANKVKAGANAAITQYFF
NADAYFRFVDDASRLGVAVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
EAIRAFGLDVVTVLCERLLAGGAPGLHFYTLNAASATKTMWQRLGL
>A0A022KSI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium muris UCD-AY4|TrEMBL
MPPISLVSPPATAPPTGRAATAPSATGTRPVRPSRDPVGQRSPSAATLPDPTEHLPAPSP
RRRPALSYELFPARTGSSFERLQQTVAQLEHTAPDYVSVTSRTGYQNFARVLELTDHVLE
HTRLRPLVHLTSVGARREHLVAAIEALLDRGVRGILALRGDVPEGHVPEDDEFPFARYLV
ELIREVERDRSALLAGGRLAIGVAAYPVRHPESPTRQHDVEVLVSKARSGADFAITQVFF
DPADYCDLVTRARRAGVEIPLVPGFIPATDPKRLHRLAELSGVHAPRELLHALECAADDA
ERRRIGTRFTVDLIRGVLDAGAPGLHLYTFNRHAEALDVLDALDLDRWSTAGTPDPGTPD
PAATPHQGDPR
>A0A2V1CE93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cadophora sp. DSE1049|TrEMBL
MHIKDMLAEAERSGEPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVSVAQSHHGLETCMHLTCTDMGQDAVDAALKDAYKAGCTNILALRGDPPREKEK
WEATEGGFHYAKDLVKHIRDTYGNHFDIGVAGYPEGCDDQDDPELLLEHLKQKVDAGATF
IVTQMFYDAENFIDWMGKVRAKGITIPIVPGIMPINTYASFLRRCNHMGCKIPPEWSATL
EEVKNDDAAVRNIGTGLVTEMCRKLLAAGIHHLHFYTMNLAQATRMLLEELNLTPSEQRP
LKQALPWRQSLGLGRREEDVRPIFWKNRNKSYVTRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNRRLWGEPKSIKDVADIFVKYLEGGVESLPWSEAPINSEADSIKSDLIA
LNKRGMLTINSQPAVDGVKSSHPVYGWGPSNGYVYQKAYLELLVSPTLMTQLIARIELDP
DLTYYAVNRAGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHSSLSPSRELIENMMDTWYLVNIVHNDFHQTHGLFPLFDGLEVKDIDVPFAAPTNGI
ETNGVNGITPAPAAGIENVPLTNGTAASAAH
>F9LYL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis bv. 2 str. SK95|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGMHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A4Q8RN65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinilabiliaceae bacterium JC017|TrEMBL
MTVAELIKTSKKTGFSFELLPPLKGNSIDKVFHTIDLLKDFNPLYINITSHRDEVIYKDA
EKGLYERRVIRKRPGTVSVATTVQHKYNIKVVPHIICSGFTKSETEYALIDLNFLGIHDL
LVMRGDNSQGDRFFTPTIEGNVHAIDLIRQINDLNKGHFLDGTDMEPFETPFSYGVAGYP
EKHKEAPNMESDLHYLKEKVDAGAEYIVTQMFFDNSKYFDFVDRCRAMGITVPIVPGLKP
INLQNQLSALPKIFHVDIPEDFAREIRKCKDEEAVKQVGIEWCIAQAKELMQHHVPVLHF
YSMMAAQSVRKVAEAIY
>C5DIA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)|TrEMBL
MHAPRKLNKCGQGTALKLIMSTIKQRYESTDGPFISLEFFPPKTKLGKQNLTARMTRMTA
LNPLFITITWGAGGTTAKKTLELATVAQRELNVPVCMHLTCTNTNKEIIDEALKLAHEAD
IRNILALRGDPPVGEEWETPSESSEFQHAVDLVRYIKEKYNDDFCVGVAAYPEGHCEGEA
DGVAQDPRRDLGFLKEKVDAGADFVITQLFYDVEKFLSFEQMFRNEVSADIPLFPGLMPI
NSYLLFNRAAKLSHASIPQAIRDRLPQEYHSDDNKVRAIGVDILVEMVEEIYKRTEGRIK
GIHFYTLNLEKAIAQIVTKSPSLSKILEEDKEDDLVEGVGEIALVDGNTLEEDENVKKRR
RQSSHNDDLTCNRVLLDEAGKSIASGRESSGAPSRKVVISISQGSGALGKDATWDEFTNG
RFGDSRSPAFGEIDGYGPSLKVSSKKAYEIWGQPSSTDDIKTLFIRYLEGSLEALPWSDL
GLSAETALIQEELIQLNERGYLSLASQPATNSTPSTDKIFGWGPPGGYVYQKSFVEMFVH
KQQWELEIKPKLEPLGSKVSYYVGDSAETFYTNLDSSCSSVVTWGVFPNSEVLQTTIVEE
ESFKAWRDEAFSIWLEWSKLFPRNSRSNTLLKQMHRDYYLVSIVHHDFSDCDALWDLLLA
>A0A1V2EWM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas jeddahensis|TrEMBL
MTLSINQLEEARRALEAPLFADVAGDVDVSFEFFPPKSEAMEKTLWDSMATLAPLGPRFV
SVTYGAGGSTRERTHATVARIARETNIPAAAHLTCVEATKAEIDAVAEEYWAAGVRHIVA
LRGDPPTVGARYAAHPGGYENAAALVEGLRRLHPFEISVACYPECHPDSGDAAIDLDNLK
RKMDAGATRAISQFFFSPDVFFRYRDAVAAAGIDAEIVPGIMPVSNFAAVQRMSKMCGTD
VPAWMGRLFTGLDDLPGARQLVSATLAAELCRKLYAGGVKQFHFYTLNRAELSFAICHLL
GVRATPEVALAAA
>A0A357NCY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
AVELDPPFNADPETVLHNARLCKQHGVDVITIADSPMGRARVDSVMLAAKVKREVGIEVI
PHICCRDKNINALKSTLLAGYMENIRNVLAVTGDPIAAAERNEVKGVFNLNSLRLMELLS
IMNKEVFAAEPVNIGGALNLNVPQPAEELLRLCKKKEMGAGFFLTQPIYDDGVIDFLSRI
DRQAHRYILGGVMPLVSYKNAQFLNNEVAGIRIPDRIVRRFDPRMSREEAENLGGEIAVE
IAGRLRNHVHGFYFITPFNRAGMIVKILQRLNLA
>A0A1S1EI80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC034A01|TrEMBL
MFEASPSTRLSASAPLDREGAQLIRRPRPKRQRTALSFEIIPPRPTDDAGKIDQLIAGLA
EYKPDYVSVTSSRRSEWLEGTAAVISRIAETTDLRPIAHLACTAGTRDEMAEWVRVLIDA
GVRGFLALRGDLPETGLPADHLQYATDLLNLIQDVQEEEAFRLAAGKLALSVACYPKGHE
ESRNLDHDLDVLLTKQRLGADFAITQLFFEAQDFLDFVEIARLAGVRIPLIPGIMPMTSL
KRVRRMGELSGLEVPVGVEKQLLEADDEYEAGMQLTANLAREILDAGAGGLHVYTHNNLD
VTRDFLDRIGIDKGQQ
>A0A7I8MUB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis associated proteobacterium Delta 3|TrEMBL
MIVAKRKPFDEIMELLQDYKKVLTVGCGTCVAVCLAGGEKEVAVLNSELDMARKLADNPI
ELGSTTLERQCDREYLDELASKVDEYDALLSMACGVGIQFLAERYPEKPVLPAVDTSGLA
VNQSVGFYEERCRSCQQCVLGWTGGICPVTMCAKGLYNGPCGGTNLGSCEIDPEQPCAWY
MIHERLAKQGRIDNIKNICSAVGWKDTVPRTLIQPGYKKPEEEGA
>A0A1H1GBQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter crystallopoietes|TrEMBL
MSPPTPTLPYIDAEITNHPALSYELFPPRNAQAEETLWRTIRELESTAPDYVSVTYGAGG
SNQGTALELLERLQNETRLRPLAHLTCVGSSGVELARTIEAIIGRGVRGILALRGDAPAG
SSGRPSGELRYAQQLVELIRRIERQRTAHLAAGKVAIGVAAYSSRHPESPSFEHDVEVLL
AKQSSGADFAITQIFFDANDYSSLLRRARQAGVHIPIIPGIMPLTSVRRLDRLAQLAGID
VDLAVRDRLASAGDDSTRQRIGIQATVDLANAALDAGAPGLHVYTFNEHVSALQLLEKLQ
LPRPAAPVRHKVLARA
>A0A086WDV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. BSC265|TrEMBL
METPNFSIEFFPPKTEEGAEKLRVVRQKLAELQPKYFSVTFGAGGTTQQGTLQTVLEIKS
AGHEAAPHLSCVGGSRESLRAILQQFQDNGIRRVVALRGDLPSGYGGGGEFRYANELVEF
IRKETGDWFHIEVAAYPEMHPQARSPQDDLQAFARKVQAGANAAITQYFYNADAYFDFVD
NARKLGVDVPVVPGIMPITNYTQLMRFSDMCGAEIPRWVRNKLASFGDDTASIKAFGLDV
VTGLCERLLAGGAPGLHFYSMNQAVATTAIWQRLVK
>A0A7L5RXQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ABC1|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLAGYNPDFFSCTYGAGGSTRDRTVNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYRDNGIKRIVALRGDLPSGMGMASGELRYANDL
VEFIRTETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKAQAGADSAITQYFFNADCYFY
FVERVRKLGVELPIVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDIESIQAFG
EQVISEMCEKLLAGGAPGLHFYTLNQAEPSLAIWHNLKLSN
>A0A7C6A808|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurella acetivorans|TrEMBL
MSFASLIGKKKLLTIEFNPPKNTNISKFILELEQFRGIVDAINVTDSPMAKPRMNSIVSS
NFIKHISEPIFNLTCRDKNKIALKSDLLAAGALGLKNILAITGDPAKDSSSVYKINVFEL
IGLTQSLSEQFNINFFIGCASNIPNQNTISSIKTRLKRKADLGAKFVITQPVFSQDDLER
FLEATSQISIYKIIGIMPILSYKSALYLHNNVKGINIPKSILYKFENASKEYSRLMALDL
HEKLINDISNLLPYIEGLHIMKSDYEIVNLTKKYLEV
>A0A0E3QEP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. Kolksee|TrEMBL
MLFNFREKLNSSKFLVTAEVSPPKGTRFSVPLEDAHQLKGIADAINVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICVMTGDFPSCGDHPGSKP
VYDLDSVQLLQLVRKLDSSINFAGNKLDGGTSFCAGAVSGIDPEKPLQLIKLEKKVSCGA
DFIQTQAVYDVGMFEEFMEAISHLEVPVIAGLIPLKSLGMAEFMNRNISGIHVPEEIMLR
IKDAPDPVEEGLSIASETIKELMKLSRGVHIMPIGSHKNTARLLSMAGISGK
>A0A4Z1BT45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter confluentis|TrEMBL
MESQKQFKRRFSFEFFPPKTDAGKEKLQTVRGQLAEVDPDFFSVTFGAGGSTRDRTIETV
INLHKQGISTAPHLSCVGGTRQEIGELLDLYRENGVNRIVALRGDMPSGMGAAGELRYAN
ELVSFIREHSGDTFNLEVAAYPEFHPQARTAEEDLKNFARKVEAGANSAITQYFFNPDSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSESIRQ
FGEEVVTNMCEKLLEAGAPGLHFYTLNQAEPSLSIWKNLGIGERERIPF
>A0A2N3T560|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimarina sp. MAR_2010_214|TrEMBL
MKVTDHIRKAKDKTLFSFELIPPQKGRSIQELYNNIDPLMEFNPPFIDVTTSREEFIYID
REGLLDKKLTRMRPGTVGICASITHKYNVDTIPHVLCGGFTKEETEYLLVDCHYLGIENV
MALRGDAMKEEKYFTPTKGGHNYANELVEQILNMNKGQFLHEVIETDNKSDFCIGVAGYP
EKHMEAPSVDSDIRRLKDKVDAGADYVVTQMFFDNKRYFDFVKRAREAGINVPIIPGIKP
VAVKRHLQLLPQVFKLDMPDELVRAVEKCKTNKEVREVGVEFAIQQSKELMEYGVPVLHY
YSMGKSDNIRKIAEGVF
>A0A0T9UQ72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia frederiksenii|TrEMBL
MSFYHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIAADYWNSGIRHIVALRGD
LPPESGKPEMYASDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A3D2Y265|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp|TrEMBL
LDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKLYEGLDADDQTTRNLLGANIAMEQVKV
LAKEGVKHFHFYTLNRSELSYAICHMLGVKPQNAG
>A0A4Q6FI03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium|TrEMBL
MQPISFEFYPPKTDEQRAQLDRSVQRLKEHAPQFMSVTFGAGGSTLGHTPETVQRLRSEH
GVAGVPHLTCVGGNREEIRSLLKLYRALGCDRIVALRGDTPSGMVRSGDLRYANELVELI
RAEHGSQFRIEVAAYPETHPQAEHAMADLRNFKRKVDAGADSAITQYFYNTDAYFRFVDD
ARALGIDIPIVPGVMPISNFSQLRRFSEACGAEIPRWVVQRMRGYGDDAEGIREFASDFI
ARMCERLLAGGAPGLHFYTLNLSKPTLNVLARMARIRLWFSG
>A0A1V2K4T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cedrina subsp. cedrina|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIQRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGADSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISTMCEKLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A518G391|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureliella helgolandensis|TrEMBL
MSLAKLFSPDRCVLSFELFPPKSDDGVQDLLNTVVELNAQRPDFFTCTYGAGGSTRDRTL
TITSQIRATHQVPVASHLTCVGSTRDQLREYLKTARERGIDYIVALRGDPPKGEASFTAV
AGGLRYANELVELIRNEFPHFGILVAGYPEVHQEAVDATSDMANLVRKVDAGADAIVTQL
FYDNDDFFRFRDQCVAAGIRVPIVPGLLPVLSLKQVQRIASLCKAKLPNEFLSRLQQTED
LEAQFEIGVDHAAKQTQGLIDSGVPGIHFYVLNKCLATNQILGRVTGLQR
>A0A4R2TQC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. PP-CC-3A-396|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGISFEFFPPKSEKMETQLWEAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPATKVAAA
>A0A3D5F5D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp|TrEMBL
NSGERDRTHDVVKRIQQQTGVTAAPHLTCVDATADELRQIARDYWDSGIRRIVALRGDLP
KGVEKTDMYASDLVALLKEVHDFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTGVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKLYEGL
DADDQTTRNLLGANIAMEQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVKPQNAG
>A0A1G1NGP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium RIFCSPHIGHO2_02_FULL_67_20|TrEMBL
MGLPEADRFQSKLGKKRFLVTMEVNPPKGTDLSEMLSAVGRVRGLVDAVNVTDGSGAIMR
ASALAVSKAVLDAGVDPIFQMTCRDRNRLALQADLLGAAMLGIRNLLLLTGDDPKAGDHP
DAKPVFDINSAALMQVAKGLTEGKDMAGKELAGRPSFCIGAACDPGAKDIEVEMQKLQAK
IQGGAEFFQTQAVFDPPKLQAFMARVRSSAPSGLQKPVLAGILLVKSAKMARYMNEHVWG
IHVPEPVIERFERSADKRAECLAVTVELIRAIRDSADGIHLYALGWEDLVPEILKEAGTE
AVK
>A0A7K2TXX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8358|TrEMBL
MALGTPSTWTDHARTVRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTREGTVRATQQIAADSTLTPVAHLTAVDHSVAQLRNMVGQYADAGIRNILAVR
GDPPGDPMAEWVEHPEGVRYAADLVRLIKESGDFCVGVAAFPERHPRSADWDSDIRHFVD
KCRAGADYAITQMFFHPESYLRMRDRVVAAGCDTPVIPEVMPLTSVRQLERFPQLSNASL
PSALKDRILAVKDDAAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A3R6XNA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM05-9|TrEMBL
MKLKEYIQTKRIIADGAFGTYYISLYGDGSRAENGAGLSNLPELANIKAPERVIGIHTEY
IEAGAQFVRTNTFASNTKSLSADMEKVKENIRAAVMCAKMAAGKVDREIYLAGDIGPIPV
EGMLHSDRLTQEYIAIGETLLSQGIDILLFETFPELETILPAVTYLKENHDCTILVHFSV
NQFGYSNTGLSAKRLIAEANACPYIDGTGLNCGVGPGHMEKLIRKIVPDDTTFLSVFPNS
GYPKYLNNRLTFTDNAEYFTEKMEEIAALDVGIFGGCCGTTPEYIRRIAAGISADHPVRK
TETEAEKITVSEHPAYGFMERRVKEPAHKLIAVELVPPLNANDEKLLDAAHILKNAEVDV
VTFPDSPSGRTRADSVLMAEKIRLETGLCVMPHICCRDKNAIAIRSTILGSSLNHITNFL
LLTGDPVPVLFRQTTKSVFNFDSVGMMKIVQEMNSDTFTDHPVTYGGAINHNRMNTKAET
ERIRRKMAAGATFFMTQPIFSAEQADVIRQMKKETGATILVGLMPLVSRKNAVFMKNEMT
GIEIPDTIIERYREDMSREEGEACGVQIAREFMAVTDDFADGYYFSFPFNRVHMLKKILK
>A0A1J4P1Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces mangrovisoli|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMADWVPHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVRHFVD
KCRAGADYAITQMFFQPESYLRLRDKVAAAGCATPVIPEVMPVTSVRMLERLPQLSNAAI
PAVLKERILTAKDDATAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A2N3Y8I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora spinosa|TrEMBL
MNANAEQLEQYLMNARFEVLPLRGAVEQAEQLPPGTTVTITASPSKGTEATLDVAAQLLG
RGLHAVPHLAARLIADTAHLTALLDRVDALGLSEVFVVAGDPPQPRGEFPDALALLRAMD
ELGRRPARVGITGYPERHAFISDASTIRAMTEKSRYADYVVSQICYDPHTVASWVKDVRA
RGLALPIYIGVPGVVDAHKLLRISLKIGLGDSMRFLRKQHGVVSKLLTRYTPEELFDGLS
PYLVDTTCGIAGWHFFTFNEIAKTVQWRHDLVARLREVPA
>A0A1G0ABA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteria bacterium GWF1_32_7|TrEMBL
MKVTEHIQNANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LANGLLQKKVVKKRPGTVGICAGIQNKYQVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGHAYASELVTQISNLNKGIYLDEDLQNSTKTDFCIGVAGY
PEKHMEAPSLDSDIHFVKQKIKNGADYIITQMFFDNKKFFDFVTKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSVELPDDLIMAVVKAKDNDAVKQIGIEWCTQQSKELVAAGIPVLH
YYSMGKAENVKAIAKEIF
>A0A255XN98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elstera cyanobacteriorum|TrEMBL
MSDDLAISFEFFPPKTPEMEVSLWNAVEKLAPLAPSFVSVTYGAGGSTRERTHATVRRIR
QETKLEPAAHLTCVAATRAEIDAIARDYWASGVRHIVALRGDTPTGGPYEATPGGYAYAA
DLVEGLKRIAPFEISVAAYPEGHPEARSLDADLDVLKRKVDAGATRAITQYFFDVDVFTR
FLERARAAGISIPIVPGILPVTNVAQVLKFSKACGTSVPQWLADTFEGLDADPETRKLVA
ASVAAEQVLKLRAEGISEFHFYTLNRAELTLALCRRLGVRAPAAV
>A0A174CK34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes finegoldii|TrEMBL
MNVVDIINKAISERRTRFAFELLPPLKGDGCCGVFGSIDRLIGFDPAYINVTFHREGIKQ
AVRPDGSVEWHVVRRRPGTVGISAAIQKKYDVEVVPHLICGGQSKYDIEDALIDLDFLGL
HNVLALRGDKSQNEKFFMPHPQGHTHAVDLVRQIAAMNRGQFVDGEVEECHHSKFSIGVA
GYPEMHEEAASPEADIACLKAKVDAGAEYVVTQLFYDNARFFDYVRRCREAGITVPIIPG
IKPLSTVRHLTLLPQTFGCHIPEELGREVLRHKDDPKAVREIGTEWAVAQSRELVEAGVP
VLHYYPMGKADNIIKIAKAIF
>A0A4Q9EMG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hafnia paralvei|TrEMBL
MSFFHANQREALNQSLAELHGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGGGKPDMYACDLVSLLKEVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEVHVPI
IA
>A0A1M3PJV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. 66-54|TrEMBL
MAHATLDRAALARLMTDYSLEITPKDVEALENAAHMIPQGTLISVTFLPGAEFADRARAA
ERIQQLGFKPVPHLSARRLLDPDNLREYLDLLKTKIDLKHVFVIAGDPNEPLGTFEDALA
VIDSGILKDYGIEHVGISGYPEGHPDITNEKLAKAMHDKVASLKRQGIAYSIMTQFGFDA
DPVLAWLKQIRAEGIDAPVRIGVAGPASIKTLLRFAARCGVGTSAKVVKKYGLSITSLIG
NAGPDPVIGDLTAQLGEEHGQVHLHFYPFGGLVKTNEWIVDFKKKQGL
>A0A3N0I5E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Absicoccus porci|TrEMBL
MSIIDILNNNKVTISFEVFPPKKETNFDEVEKAARQIADLHPNFMSVTYGAGGTNNKNTA
HLAADIQNKTSTPVLAHLTCVSSTKEQVASVVHTYEDLGIDSIMALRGDLPKDGKVSPDY
THAIDLIRDIKAINPNLCIGGACYPEGHVECERQSEDIQHLKEKVDAGLDFLTTQMFFDN
DTFYNFMFKIREAGITVPVLAGIMPITKKRQVARSVALSGATIPHKFRRMVDRFGDSEET
MKQAGIIYASEQIIDLISNGINHIHVYSMNRPDIAAGIIQNLSSIIDYDRIKK
>A0A8C0Q904|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Canis lupus familiaris|TrEMBL
MDQPPPGVLPATVRCSRLGLWTLEAGRVGFSVPPSISRSPAMVKEPRGDGDGGPTPRSEG
SSSGSESSKDSSRCSTPGLDPERHERLREKMRRRMESGDRWFSLEFFPPRTAEGAVNLIS
RFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQI
TGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYP
KGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFP
IQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGL
HFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSSYIYRTQEWDEFPNGRWGNSSSPAFG
ELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYLSGEPNQHGYKVTCLPWNDE
PLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTS
RETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGFMFWKDEAFALW
IEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLKGPSPERE
AEAV
>A0A2E1U312|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiritimatiellaceae bacterium|TrEMBL
MSLLETLQHNPLIGDGAMGTMLYAKGIFINTCYEQLCLTKPELIERVHRDYVEAGADLIE
TNTFGANRLKLEAHGIADQLEAINRAAVHLARKVAKPNTYILGSVGPLLQSDQLFSDRHT
SELEQLFHEQIALLADENVDAIQLETFTHVDEAELAARIAASYNLPVFVSVTVGKDGETR
RGERIEQIIRQLDACDAVDAIGINCGLGPAAAFSIAERALPLTSKPFSVNANAGLPQEVD
GRLIYMSTPEYFSEYAKRLIELGVRMVGGCCGTTPEHIATMSKQVKSLSGVKEHIQITHH
TDQETPPIKTIPTTAKCRFGAKLVAGEKVTSIEITPPRSIDLQPMLDKCQQCHDAGIDAI
NIPDGPRASARISPMVAALAVEREIGIETVLHYCCRDRNLIGMQSDLLGGYAGGLRNYLI
VTGDPPKLGDYPDSTAVFDVDAVGLTQVVNNLNHGIDVGGNQINPPTGLLIGVGANPCAV
EPERELNHYLNKINAGAEYAITQPIFDANALLRFLDAAEKKGASIPVVAGVWPLVSYRNA
QFLKNEVPGVEVPDALLERMSHAKTKEDGRALGIEIAREIRDAIADRVAGFQVSAPFGIV
DLALQVLD
>A0A6I5ZUG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorella glycerini|TrEMBL
MKTESKLEKLLSQGHFVVSGEIGPPKHANPEGIQKHTALLKDYVDAMNLTDNQTAIVRLS
SIAAGVHVLQAGGEPIIQMTVRDRNRIALQSDLLGAYSLGMRNVLCLSGDHQSFGNHPTA
KNVHDVDSLQLIKIVKDLRDEKKFACGEELKGNEPRFFIGAAANPFADPFEFRVLRLEKK
INAGADFIQTQCIFDMERFERFMAMVRERGLHKKAHIIAGVMPLKSAKAAKYMQQSVAGM
IVPDEIVSRMEKAADPRAEGVAICVEQIKHLQTIEGVAGVHIMAVMWEEIIPTIVKEAGL
YPRPKAE
>A0A7Y8SXU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSLTVSFEFFPPKTEAMEQQLWASIRRLEPLRPAFVSVTYGAGGSTRERTHATVKRIIEE
TRLLPAAHLTCVAASRAEVDEVVHGYWQAGVRHIVALRGDMPDMSRPYRPHPEGYASTPE
LIRGIRAIAPFEVSVSAYPERHPDSVSIDADLDLLAAKVEAGASRAITQFAFDTGAHVRL
RERAHVRGIRVPIVPGLMPATNFKGVQRMAERCGAAIPGWLAERFEGLDEELDVRKLIAA
AIAAQQVTQLKGEGFDAFHFYTLNQADLTYAICRILGIKPEARP
>A0A8I1RMF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSLRDLPANRHPLKVSFEFSPPKTAEAEEALWRAIRRLEPLAPAFVSVTYGAGGSTRDRT
HATVKRIVDETTLSPAAHLTCVASPRCEIDEIVQRYWDAGVRHIVALRGDMPNMEGPYCP
HPEGYASTPDLIAGIRHLAPFEVSVSAYPERHPDSQSLDHDIDLLKRKIDAGATRALTQF
GFESDHVARFRDRAVDAGIKVPIVPGIIPTTNINGIARMATKAGASVPEWLLWLYEGLET
ESDTRKIVAAAVLAEQVTELRNRGFDQFHFYTLNQADLTYAACRILGLQPKKVSS
>A0A2P6MI80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalicoccus urumqiensis|TrEMBL
MNLKEKLRQGLTVGDGAMGTLLYQRGLRGCFEELNLSDPDQIQSIHEKYIAAGADIIQTN
TYAANAIKLDRYQLGDCVKEINEAGAAVARRAGSAYTAATIGGVATMHQEKTPLEDRMDA
LKEQADVLLQTDVDGFILETFYDFDELKQILSYLREHTDRAIIAQATLGDIGVLHTGMPI
EAALKELEALGADVAGVNCRMGPYHMLQSLEETDLLSTAGISVYPNASLPNVRDGRFSYQ
SNPTYFGDMTQALVEEGAVLIGGCCGTTPEHIQEIRQAIIRGRLTPPQEKQVRRNRTAVK
EEVSGDREPVKLTETSREQTSVIVELDPPKALSGVPAFMEGARALTEAGATAVTLADNSL
ASSRIDNLALGTKIKDAGSRPLLHVACRDRNIIGLQSHLLGLHELGVRDILAITGDPAKV
GDFPGATSVYDMSSMDLVRLIKQLNEGQSFSGKDLGAKTNFTVGAAFNANARRLDREVQR
LEKKVQAGADYFMSQPVYSSERIEEIADAVKDLPVPVYIGIMPLVSSRNAEFLHHEVPGI
QLTDSVREQMRALSGDREASEAEGIRMAKELVDTAMKHFDHIYLITPFLRYNITAELTQH
IRTQEAAVNAAR
>A0A7W8KML6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. SJZ102|TrEMBL
MSVLKQVLNEGRFVCVLEIIPQQSTARLAALERIVQRGHLAGWPLLPAFSDRVGLRSDLS
PLAGAGALGDPASSLLHFSGKDRERADLLLQMEAMQARGLRQLLLLSGDRLPGHRPGQAP
VRYLESVPALQLARAHGPDWLLGAALNPFKYREEEGGAQYLKAQKKLLAGADFLTLQLGF
DAAKHIEAQAWMRAQACAKPMLACVMQLTGKRAAALQKVPGIVITESMRGLLERERQVSP
AYAGARSRARLALQIVGLQLMGYAGVHVSGLHALDELLALEQAICKQRDSVASLAAWIER
WQVSWEMPDAPRVCFTPDAGAWKMGQSNVAATRRERLKYTLLSKVHGRFFSRTGWLSQAF
GWSVTRPLWQDGIAAQALHAVERAIKRPLLGCDTCGRCRLQDTLYICPETCPKGLANGPC
GGTHLNRCEFGDRECVHGVKYRIAKSAGQLPVLALTLIPDIEAGHRRRSSWPEWFARVDS
TSRQACKRR
>A0A3N1PTF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PanSC19|TrEMBL
MALGTASVRSDRARTVREILAAGDTSYSFEFYAPRTEKGEQVLWNAMRRVEAVGPSFVSV
TYGAGGSTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNILGQYADAGIRNMLAVR
GDPPGDPLGEWIEHPEGVKYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVTKAGCETPIIPEVMPVVNVKTLDRLPQLSNAVF
PPDVKERILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A1H4GIV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga terrae|TrEMBL
MKVTEHIAKAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPSFINVTYHRSEHMFKKK
ADGSFEKVEIRKRPGTVGICAAIMNHYNVDAVPHLICGGFSKEETENALIDLNFLGIDNV
LVLRGDAPKNETFFEPDPHGHSYAIELLNQVAQMNNGVYLEDDLQGGVKTNFCIGVAGYP
EKHFEAPNMQTDMSYLKKKVEQGADYIVTQMFFDNQKFFDFVARCREMGITVPIIPGLKP
LTTRKQMTMLPRIFHVDLPTDLSNEILKCKSDKDVELVGTEWLIAQSRELKAFGVPVLHY
YTLGKPKVVQKAVAAVF
>A0A2A4TFF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MKITEHIEKAKGKTLFSFEIVPPVKGQNIQKLYDNIDPLMEFNPPFIDVTTSREEFIYLK
KEGGLLEQKVTRMRPGTVGICASLMHKYGIDPVPHVLCGGFSKEETEYVLVDCHYLGIEN
IMALRGDSRKDE
>A0A3D4KBW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MERFQSPIHNMVNVSFEFFPPKTDEAEKVLWDNIKQLEPLNPTFVSVTYGAGGSTRGRTH
NTVKRIRQETGLNPAAHLTCVGSSKAEIEEIVRGYIEVGVNHIVALRGDPPSGDVNFKPH
PDGYKYSTDLVAGLKKINSQLEISVAAFPEKHPESQSIEEDLDYLKAKEDAGATRAITQY
FLDPYIYVNFLEKVRKRGIKMDVVPGVLLISNYNQLLKFSKMCGASVPPYITNLLQGTDE
TPHVRDMVVTYIIAELCRVIRKETGIDHIHFYTLNRAAQTIAACKLL
>A0A0A2WM02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus filiformis|TrEMBL
MKIRDLLRRAQGPLFSFEFFPPKTPEGEEALFRTIAELRPFRPAFVSITYGAGGSTREKT
LEWAERIRQMGLTPLAHLTVVGSSRQELEALLQSLKERGIENVLALRGDPPKGSSRFVPH
PEGFRYASEFVAFIRERFQDAFSLGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIEIPILPGLMPVTSYAQLRRFTEVCGASIPGPLLSRLERHQ
DDPQAVLEIGVEHATKQAEELLRAGVAGIHFYTLNKSPATRMVLQRLGLTPPPSSPIPPG
PPPAPGGPGAGPA
>A0A4U0HAV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. CAU 1506|TrEMBL
MADPKHASSDAARALLDDFSLEMTGKDVPALEDAAGAIPPGTLINVTFLGNEDLPMRVSA
AAAVKRLGFVPVPHVSARRLASQAELEDFLQALSADAAPANVFVVGGDPAEPMGPYPDSL
EVIRTGLLAKYGIRRVGISGYPEGHPDISDDVLWQALENKYAELQQQNLESVIITQFGFD
VDPVFAWLAEVRRRGINAPVRIGVPGPAGVKRLLNYAKRFGVASSAGIVHKYGFSLTNLL
GTAGPDKFLEEFAGRYDPAVHGTVKLHFYTFGGMKATAEWVTDFRGGR
>A0A1G1T3I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter glacialis|TrEMBL
MKVTDHLDRANGKTLFSFEVLPPKKGENIHTLFSNIEPLMEFKPPFIDVTYHREEYVYRH
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDS
VLALRGDPIKSEGIFKPEPDGHAYAADLIGQVADLNKGEYLDQEQDDSWATGFCIGTAGY
PEKHFEAPNYQSDIRYLRHKVDRGADYVVTQMFFDNEEFFRFERLCREAGIMVPIIPGLK
PLTSKSQLTMLPRTFYLNLPEPLVEAISQCRDNEDARRIGIEWCINQSRELMAHGVPCLH
YYSMGKSESIRRIAAELF
>A0A651GXU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneolaceae bacterium|TrEMBL
MKVIEHYEKATEPLISFEIIPPKRGGSVQTIFESLDKVVDKVKPPFIDVTYHAAEAYVEE
QADGTLKRMVRRKRPGTIGLCAAILHRYGIDPVPHLICEGFTREESEDALIELNYLGIHN
ILAIRGDNNGSQVSLNLNGTANKYAIDLVKQIRQMNEGDYIEDIVNAEPTNFCVGVAGYP
EKHFEAPNLDWDIKRLKDKVDAGADYVVTQMFFDNSAYFSFVEKCRENGIDVPIVPGLKI
LTTNNHLKSLPKYFHLNIPDVLTAEVDANPERAKEIGIEWAQKQTLELMEAGAPGIHYYI
MGDPQPALDVIDFVQKK
>A0A379V0X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MEQTLWNSIDRLSSLKPKFVSVTYGANSGERDRTHSVIKGIKERTGLEAAPHPYLY
>A0A1E4KPW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium SCN 69-123|TrEMBL
MTALSFEFYPPKTDDQRAQLDRTASKLKVHAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLQAAPHLSCVGGTREEIRELLKLYRAIGVRRIVALRGDLPSGMGFPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLRHFKAKIDAGADAAITQYFYNADAYFQFVDA
AGKLGVDVPIVPGVMPISNFSQLRRFSEQCGAEIPRWIAKRMQAYGDDVDSVRAFGADVV
AALCERLIAGGAPSLHFYTLNLARPTSAVLQRLGHG
>A0A3D5JH90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MATSIETIQTAASNWSIEVTPTGATKIESFSDCLDAGTTVNVTFLPGTDPADTIAVCERL
HNDGMRPVPHLAARSLRDADQLEELLSAYTSRCGVEEVLCIGGGVDNPVGAFDATMQVLQ
TGLIQKHGIRHIGVAGHPEGSPDISDDEIAEALGAKNELAKAEGLELYIETQFCFEADIV
LDWERRVRAAGNALPIRIGIPGPATIKTLFRFAQISGIGPSMRFISKQAKNVAKLMTVQS
PHLLLTGLAEGMAADEECLIRHFHFYPFGGFARTATYAGAIADGNIKMLPKGGFEVIDG
>A0A2E0YAZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MDVASLYRNATGGLPFSLEILPPNRGLGLNNIHDFFNNLHEWLPAFVSVTYHQAHKIDII
DNNGQMEQIWNRKKPGTLGVCAMLKFQYGLNVIPHVICGGFSKFESEDFLVDLDYLGLKH
ILALRGDPNKTETQFNPHPQGYAYANELVEQIVDMNAGKYVEDVKEARPTDFEIGVAGYP
EVHAEASDLHDDIINLKRKIDSGASFVITQMFFDNACFFHFDKTCREMGIHVPLIPGIKV
ITSKRQLEVLPEIFGTKLPKKLIDDIMACETDEEVCQVGIAHAVNQTKGLLEYGVVGVHF
FTMNNSQVFNQVLQQFQE
>A0A2I2Y6Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gorilla gorilla gorilla|TrEMBL
MDHRKARVFPAGHYCPSLGIWASQVGSVRSSVPPSISRNPAMVNEARGNSSLNPCLEGSA
SSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDICVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDTLELLNRPTQNARETEAP
>A0A534JDG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MGTPAADRTQKSGSRLERVLASGRFAVTAEIVPPASPDPTAVVSIARRVAGFADAYNVTD
SPRARVHMAPWAGAALLLREGLEPVMQLATRDRNRIALQADVLGAAALGVRNIVALSGDD
PKSGNEPEAAAVFDLDTEDLLEVLRDLRDKGVLRGGDSVDPRPAIFIGATANPFGGPMED
SFVNLRGKAEAGADFVQTQAIYDLDAFEEWMHLVRKEWLHEKLHILAGIVPLRSARSARF
MKEKVPGVVVPSDIIVRIEKASDPRAEGLRIATESLESLQKIEGVHGVHIMAVGWEEAVP
LVVKQSGLYPRPAA
>A0A7T1QN03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter hormaechei|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMFAADLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A519D4W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MRLRDKITKAQRPVVVYEILPPRIIDGTIESYAERISTLLSQTHVDAINIPEVRAEETRG
VRPVEEVIRAEPREFGRLLQESVGIETIVNRVTVHENAKEQEKWFVTTYEKFGVKNLILV
GGESSDIDYPGPSIIESASIIGGINKEKGRDVFFGGICIPSRKVESSRMMQKARNGVEFF
TTQVLYDGSDICKMLGHYSKECLDKGVDAKRVLLSFAPISNQKNIEFLKWLGVNIPIETE
DYLLENLEETKARSIEVSIGIMEEILEYVSENNISVPLGLNIEHIMTYNFKTSVELLQKM
SKRYRIYCMNSSPIAK
>A0A4U1GFI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter hiemivivus|TrEMBL
MKIIDHINNAKGKTLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDNAFIPTPNGHAYASELLQHVADMNKGKYLHDDMESAEKTDFCIGVAGY
PEKHFESPNLDTDFKWLKHKVDAGADFIVTQMFFDNNKYQEFVDKCRANGINVPIIPGLK
PITSSKQLISLPKIFHLDIPLELSEAVQACKSEKEVKEVGIEWMINQCNELKAMGAPVLH
FYTMGNPEPTKRIARAVF
>A0A1E9E5L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC069C03|TrEMBL
MTTVHPALSFELFPPRSHASCESLLHTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSNAE
LHRIGVDYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEY
A
>A0A401WZW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter pasteurianus NBRC 3278|TrEMBL
MSLSRLSVELIPRSAEALAADVATVKAAFPAADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQPGLEEILVVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMQGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLDANIQFAQTVLKELAQEKGKAYLMPVRIKLEQY
LPALLDAVA
>A0A443TUQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter venerupis|TrEMBL
MFETLIQKLQEDKYLTLETTPQHEPSMHNIIERIKKFKLQDRVDGFSCTDNPLAKLKYNA
LFASLKLQMEFKKPVIATMTMRDRNKIALQSDLMGANDFDVRAILALTGDPAKMSDQPHA
KGVFEANSLMLLKIIKSFNYGMDMSGHPFKIEPKQIFPFSVTNSYAKNFSSLEKKMHLKI
QNGAMGIISQPIFDIENAKKLLESFNIAKEGVEGDKKKAQLIFGLFPVTKLRTALFLSAQ
VPGIHVPQFWIDALEAAHNISEEEEYKVGMQLSQDLFRDLNKLHPKIHLMTANRFDVANE
IIS
>A0A1H1QDU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sandarakinum|TrEMBL
MSQEVLTTLLKSARYEILPTAGVVDRVHEYVAPGRVITVTASTGLTLEATLSTAEQLQAL
GFHAVPHIAARMVQGRSELEEIVDRLTQAGIDRIFVPAGDATPPAGGYAGALDLIIDLAS
MAAPIQHLGVSAYPETHPLIPDDVTIQAMWDKRDYATHLVSNLCFDPGTIATWLARVRAR
GIDLPLVLGIAGKVELAKLARVASKIGVGESTRFLRKNTATFTRMAKPGGYNPRKFLDKL
APVLDNPALGVTGLHIYTFNQIKDTEIWRRKQLGMVDEVESVQ
>F8HCQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius (strain 57.I)|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHEATHSLFKHHSQVSAL
>A0A3R9LCS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus cristatus|TrEMBL
MVNRQTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLAE
FISNDLEIPTIAHLPAVYLTKEMVSNILQALDRVGVNQILALRGDIFPDVAPKDDFKYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRT
AGLAYAVDQIVDLVTHDVAGIHLYTMNNAATAYHIYKATHALFNHTPSVQSF
>B6W005|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei DSM 17855|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKNGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNIEQDLYWLKKKVEAGADYVVTQMFYDNQKYVAFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAIKCKDDKEARALGIEWCVNQCRELIAYGVPGIHF
YTVGAVENVKEVAAAVY
>A0A812VU24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiodinium necroappetens|TrEMBL
MAPRRSVSWLLLAANLHLTAGRGITITPSSISAKKQTQITFTGAKNGDKVFFTKAECSAV
TDDAAAVIKNGRAAITVAEEASGLKLCLKPAGGAIAEQAGVSLNVIKPTPPSVVESVSRS
SITRGVTTSVTLKGAQANAKAVFVPVEKDCSDASPKAVLNVDGKGSFTIPTAGKTGEYKL
CYQSPGGSDSVQQTAAKGVVKLQVQESATTSQDEITGISPSLITVNVPTVVSFTGAATGD
KAVFVHSASSDCAAVTPEKDVGAGHAMFTITTAGEYTLCYRSAGAQDSVAQNGEGVKLQA
RAVLDLPGMGPASFYVAFALTFETVAVVLLVPLVLLLAGKFLVIEVFVTLDTVVMVDIQW
ALNRRGKMAQTFADDHKIDELVEKVPAGWFSFEYFPPKTAEGVENLRKRIVKMKALGPLF
TDFTWGAGGSTSELTLKLTSAAKNEFGTVANMHLTCTNQSSEMTENALKECKQLGVRNIV
ALRGDPPRGQEKWTATEGGFSSALDLVKFIRKHFGDYFSISVAGYPEGHPDNIETVEGGV
AALTESEKRRARVVKDASGKETVTVCRDANFHKEMVYLKEKVDAGAGFVITQMFLDAQ
>A0A1G0WGF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_38_69|TrEMBL
MKDHSQLNLKLEKDDNRLLKSMKDGNFLVIFEVDTPLANCNIETVTSRYSPFLKAVNSIE
GFKSGLAITDRKHSSECMDILDFANEFCLENRSDHLLFISGRNKTKNSIADLIKSCWASG
FHNIVPVSGTIYKDETLKNMTGISFYESAEVISSMREDLQNNPLLNIGSVVNPFKYSQET
IHTQYYKLIKKLNLGARFVIAQSGWDILKYQELRWYLENRNYFDPCLASITMLSPEKIEK
IISGYYRGVFFSPDCLNSLNKESRLSTSQFWAAQWRRFQLYVAGLRWMGYNGVVISGLDS
EYQVNIAVSRITSILKDISSFDNWREIYRGFLSRSEMAPYPFKYYIYKNLLEENYFDKAE
LTVKDVRKCSRKERLTFNFSKLKKELFPGQKRMLNSNDIASSFYLSSKLCPKGMIHGSCG
ETNHDNTCCLCPAKECLYSRLFRLASWRKNFEPFE
>U2N4A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia fonticola AU-P3(3)|TrEMBL
MSFYHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPAQLRDIATDYWNSGIRHIVALRGD
LPPGGGKPEMYAADLVSLLKDVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGAVVG
>A0A136MJ34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobi bacterium OLB6|TrEMBL
MIFNKRGSRPFITDGSMAVELAKRGFAERPPDRYNLSSPTVVERIYHDFIQAGATLLQTN
TLFSNRFALESVMLSARVAELNRKGVWLARTASAGRVPVLGVIGPTGRLLQPLGPLNATD
AVECFREQAASLLSAGCDAIALKSFIDITELEIAISAVRAVSTDVDVIALKSFPEDAAVL
SGPYPKLFAKRITRLGIQAFGSNGTVGPQRMVGIIDALANDTIPLVAIPDVGIPTMIGGT
AVYHADPEYVGQAATRLAEHGASIVGADGGATVEHIAAIAQAVASASVGSKTPVAQVTEH
NAVPDSHPKPPTQWYTDLQSKFVRTVELDIPRGLDMSSVIEGARYLHTNGIDAVNISDGA
RARLRMNPISISRLVMDAVGIQCITHMACRDRNMVGLQSDLLGAHELDVRNILAVTGDPT
HIGDFPYASSVYDVDSIGMIRAMDRMNHGNDLMGNPLGSATSFSIACAVNPAADDIEREV
DRLAQKAEQGAIAAFSQPVFDDDALYTFLERISNIPIKFIVGIIPLRNLRHAEFLHFEVP
GMHIPSWVRKHMLENNESQQQATSAGIHLAVQMLSAVKNKVHGVYLMPPFKKYSVAVEVL
QRAGL
>A0A7S2M8D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Skeletonema marinoi|TrEMBL
MCSATATNAVDPKIIDLLNKDPEGLAHVSLEYFPPRTEQGVKNLHARMERMLTNTKCLYT
DMTWGAGGSTAKLSLELALHAQKTGHVSNLHLTCTNMEKDGDPIKGVHDALQAAFDGGIR
NIVALRGDPQEGENEWTATKGGFTCALDLVKYIRKEFGDDFGVSVAGYPEGHPNRISELT
EDEVKSMSESELSRCCTHDGITYVCKDDDYKKEMDYLKEKVDAGADFIITQMFFDAEVFK
TFVEDCRTWGINCPVVPGLMCINAYPGFKKMTKFCKTRVPKALEEKMDSMKDDADAIKKF
GVEYGAEVCRTLLDSGVKILHFYTLNLEKVVYGITDELGITSGLTEQSNESDAKDMVAVG
SAWARAGDTIKCSAGQGVVKEIKSDGAAVVEIDGKDVQLAKGSYEKVF
>A0A8H6AEM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus burnettii|TrEMBL
MLPLPLIGGLVKLRPERFAPRLMTPQSSTFNYHLFHTFAGTDTGDKMEKITDKIAALPPD
ANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGTTAQRSLELAEICQRQ
LQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNKDFT
FAVDLVRYIRQKFGDYFCLGVAAYPEGHPVDSFQDVQDPKKDLPYLVEKTQAGADFIMTQ
LTYDIEAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVKIPPHILSKL
EEAKHDDDAVKRIGVDIISNIVGGVRDIPSPGLRGFHFYTLNLEKTVSFILERCDLIPPY
SEDFDALEDGGDISAMDGAQLRSLTRRRASSINSLPHNRVIVDKLQISEGSSKASVSHEA
PATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLH
VPPSVAHRIWGFPVSREDISTLFRRHVSGELHMVPWSEGGAEEGSPGLNAETDIIRSDLL
KLIDGNGWWTLASQPAVNGVRSDDPIFGWGPPREGFVFQKPFVEFFCPSEDYQSVLKPLL
KKHGHEKLAWFAANVKGDFESSLPAQTSDADPIEMNPNNVNAVTWGVFRGKEIVTPTIIE
EVSFRAWGEEAFRIWDEWRRIYPRNSATERFLNDIQHDIWLVCVVGQDFGAGTEMGSEDE
EDEKKWMWKVLANAK
>A0A0S6WXE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. MBES04|TrEMBL
MTVTTRPAEAATSAPCGDTPLFGEMAGDIAVSYEFFPPKTEKMEAQLWDAITELAPLAPK
FVSVTYGAGGSTRERTHATVARIRRETDLVPAAHLTCVAASKGEIDEIADEYWDAGVRHI
VALRGDPQPQDNGVFRAHPEGYASAAALVEGLRKRHDFEISVAAYPEMHPEASSAQSDLD
NLKRKIDAGSTRAITQFFFSADAYFRFLDKALAAGITAPIVPGIMPVTNFAAIRRMSANT
EIPTSLESLFADLDERPGPRALVAAVAAADLCKRLYDGGVRNFHFYTLNKADQTYAICQL
LGLRPKETV
>A0A6M1RFX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grimontia sedimenti|TrEMBL
MGYSHASHLDALNQNLSDLNGDINVSFEFFPPSSEAMEQTLWASVQRLKTLKPKFVSVTY
GANSGERDRTHGIVKSIKQETGIEAAPHLTCIDASRDELRDIARDYWNSGIRHIVALRGD
LPEKSQKPDMYAADLVELLKGEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIIPGILPVSNFKQASKFANMTNVRIPAWMYKQYE
GLEDDAVTRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPTA
>A0A8J7KI92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacter rhinopitheci|TrEMBL
MKVTEHIERANGKPLFSVEILPPLKGQDVNCTFKTLDPLAELNPAFIDVTYHRQEFIYKQ
KDNGLLKRYQVRKRPGTVAICAAIQNHYKIDAIPHLICGGFTKEDTEDALIDLNFLGIDN
VLVLRGDPIKTEKNFIPEKGGNAFASDLIEQVVNLNHGKYLDDDIQETYPMDFCIGISGY
PEKHFESPNLAMDMYYLKKKVDLGAEYIVTQMFFDNHKYFDFVNKCREMGINIPIIPGIK
PLTTFNQLTKIPQNFYIDLPEDLAIEVLKAKDKEQIKEIGLEWCINQCKELLEFGVPGLH
FYTMSNSANTKKVAEAIF
>A0A2U1K4H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pueribacillus theae|TrEMBL
MSLLEKLKDGLLVGDGAMGTLLYSHGIDHCFEHLNITHEEEIYNIHKAYVEAGANVIQTN
TYAANRIKLARYGYENLVKEINQKAVQIARKAAKEETFVVGTIGGISGVQQNAFPSEDIP
FAFVEQLNALLTEKLDGFLLETFYDLEELLFVIKLIKEKTNLPIIAQLTLQEISTLQDGT
DLNEAFKQLESAGAHVIGLNCRFGPHHLTESLESVQLSENVYLSAYPNASLPDLVDNQFV
YKTNPAYFEQAAKQLRNQGVRLIGGCCGTTPEHIEAISRGLDGLKPISKKEVRQRMKVVP
IEEKQVKEKPLHEIAKERVSVIVELDSPRKLSTDNYLTGAHALKKAGADAITLADNSLAQ
PRISNLAMGIRIKQEVNARPLLHVTCRDRNLIGLQSHLLGLHTLGIDQLLAVTGDPTKLG
NFPGATSVYDLASYDLIRLIKQMNEGISFSGQSLGQKTNFSIAGAFNPNVRHVDKSVKRL
EKKIACGADYFMTQPLFSEEKIIETYEATKHLNAPIYIGIMPLTSSKNAEFLHHEVPGIQ
LSDQARELMARCGDDKEKAFATSIDLSKSLIDTALQYFNGIYLITPFLRYDLTVPLTEYI
YEKAKIQNVTTPV
>A0A4T0IDR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia ichthyophaga|TrEMBL
MKIIDKISQSRESNEPFFSLEFFPPKTEQGFVNLKSRLQRLSLLNPGFISVTWGAGGSTD
ERSLELAATARSLGLDVLLHLTCTNMHKNRIDSALDRAKQLGIDNILALRGDPPRGHEYW
IETDAAFRHSSDLVHYIRQRHGDSFCIGVAAYPECHKDSSSAAQDLNYLKLKQDLGADFI
ITQLFYDSDAFLNWLDKCATNGIEIPIIPGIMPIQNVPSLRRLANLCGAHIPSVISDHLE
PIKNDDALVKDYGVELSTSMVRQLIDKTNSEKDKYRHLSLHATHFCTLNLEKSVRRILAN
LGWSAGLDSSSLEPNGLTNKNSDALERARLGNRLVAENGSTGHDTSGAPPQLSITAHEAA
VRALHALKHHPPSEDSGLPSSNKTSSGGNSLWDEFPNGRYGDIRSPAYGELDGWGASLKT
SSQNALRQWGYPLQTSDINEIFKKYINGDISCLPWFEENLDPESNSIKDYLFKLAEKGWW
TVGSQPAVDAIESSDAVFGFGPKNGWIFQKAFVEFWVPDHQLEPLCKRLDGWKDGGYYAG
NAKGEMRSNFYEDTINAVTWGIFPGQEVVQTTIIEDVSFNAWREEAFDIWLEWSMLYSPK
SASQQLMKNVHDNYWLVSVVHHDYKDTYGLWDFLLS
>A0A0D2PHI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypholoma sublateritium (strain FD-334 SS-4)|TrEMBL
MKITQKIEKSSKEDKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPKEKVDLALEDAKQHGCRNVLALRGDPPQGKDE
WEAVDGGFVHGIDLVKHIRRKYSDYFDIAVAGFPQHMSLPEEELKKEMQWLKEKIDAGVS
FIFTQMFYDVDLFIDWVKAVRAAGITVPIVPGIAPIQTWNGFQRATSLAKITIPQLFLDA
LEPVKNNDEKVREIGTKLVADMCRKILDANIGIRGLHFYTMNLEKGTKMLLEELNLVPRI
ETIKPLPWRQSLTPNRRQESIRPIFWANRAKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTVQDALKLWGHPTTFADIASLFARFCTSDLAALPWSDQLPSSETSVIAKSLA
QINELGFLTINSQPAVNGARSDDKTFGWGPSNGYVYQKAYLEFFVSPALLSLLLAHIERD
SSITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELGTQ
WAKLYEHESTSQKLISEFMETSFLVNVVHNDFHDADAIFRPFLKAGAEYSAVKSKSTTVN
GH
>B0MEJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerostipes caccae (strain DSM 14662 / CCUG 47493 / JCM 13470 / NCIMB 13811 / L1-92)|TrEMBL
MKISELLKEKATISFEVFPPKNKEGDISSIYYTIEELAKLDPDFISVTYGAGGSSKGKTV
EIASAIKNKYQIESVAHLSCITSTKEDILTECRALKEHNVDNILSLRGDYPAGEEEKYRG
MDLEFHYASELNGFIRENFGDSFCLSGACYPEVHQEADCFRDDLEALKKKVDAGAEYLIT
QIFFDNSYYYRLVKEARKIGIDVPILAGIMPVTNAKSLLRTAKLCGCSIPFQLSTMIETY
YNYPEAMKEIGINYAAHQIIDLITNGVDGIHIYTMNKPEIAQRIFGNIPTVLKELNHD
>W7W9N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylibium sp. T29|TrEMBL
MSDTPSLKLPVPVSFEFFPPNTEAGSEKLKTVVRELGSAAPEFFSVTYGAGGSTRDRTLS
TVRDIAALGFEAAPHLSCVGSTRAGIAEILASYRAQNIRRLVALRGDLPSGTATAGEFRY
ANELIAFVRETQGTDLRIEVAAYPEYHPQQRYARRDLQHFANKMKAGADAAITQFFYNPD
AYFHFLDEVRALGVDAPIVPGIMPFHNYARIAQFAMRDGIEIPRWVALKMEGYMDDAASI
RAFGIEVVSRLCERLIAGGAPAIHFYTLNQSALTLEVCRRLASARG
>A0A2M7YI04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium (Candidatus Ratteibacteria) CG_4_9_14_3_um_filter_41_21|TrEMBL
MSKLSEALEGKKFVVTSEIGPPKGTNIEKCLEDAELLRDKVSAINVTDIQSAVMRIGSLA
ICHLLAEKGLEPVFQMVCRDRNRLALQSDLLSAWVLGIKNVLCLTGDYTSLGDHPETKPV
FDLDSVQLLKTVATLNQGHDIAGHELDGTPNFFAGAVVTPGCDPLEPQIIKMKKKIDAGA
KFFQTQSVFEPKKFESFMNDVEKFHVPVMAGIVVLKSAGMAKFMNENVAGVFVPEEIVKE
MAETKKEDRRKKAVEIAARIIREIKPICQGAHIMPLGWDALVPEIINQAELS
>A0A2J1D4E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
EMHPQAASVSADMDHFVAKVKAGADAAITQYFFNADAYFDFVDRAQAKGVRVPIVPGIMP
ITNHSQLLRFSEMCGAEVPRWIRLRLAELGDDKASIRAFGVDVIT
>A0A1A3HRX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. 1423905.2|TrEMBL
MQYGPCGGVRPDGQCEMRPGECVFPDVVPWSGRQYRAQPVQAPLVLTDFSCTPFDQADVA
ATAATLVGASDAVLVGEHQNRPDFPPTLMGRLLLEAGVSPWITLSCRDRNRVVLEQELRG
LQSIGVQTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVALAASVGMVAAVPETPTAPPVHA
RPVRLVEKQRAGASLAVLNHVPLPRMISEFMSCARSAGLSIPVIAAVAVFTDAVSAAVLE
GLPGLELDHTVVDEVLHAPDPIAAGIAAAVAEARALLSIDGVEGVNLSGLASASGTRIGA
EIKAEVGRRIKEGIKQDIKEAAVP
>F4CL56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 / CB1190)|TrEMBL
MVRTPAARTTVVERIDVDRPVFSVEFFPPKDEAGETQLWQAIRRLEPLDPAFVSVTYGAG
GSSRDRTVRTTARIASDTTLVPMAHLTAVSHSRAELRHVIGSYAAAGIRNVLAVRGDPPG
DPLGEWVAHPDGLTYADELVTMVRSLGDFCVGVAAFPYGHPRSTDPDEDLARLVAKIRKG
ADFAITQLFLEPEGFLRLRDRLDAAGCLVPLLPGIMPLTTVRTLHRGPELSGAPLPPDLV
ARLERHADDPAAFRAAGMDATTDLCEKLLAEGVRGLHFYTLNRSPATIELVGRLGLAAAR
>A0A8A8EDJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus sp. MC1865|TrEMBL
MPSTISRPTTVGELLSAAQGPLFSFEFYPPRSEEEEPILWRAVEALTPLEPDFVSVTYGA
TGSRRDRTIHATRRIATENGPLTVGHLTCVDQSKADIAEALAAYRDVGVTNILAIRGDMP
GGGEWVRHADGLANATELVRFIKEQGDFCVGVAAFANPHETTEDPELDDRILLAKVEAGA
EFAITQLFFDAQSYIDLVRRVRALGCSIPIIPGIMPLTVISQIERFAGLSGRALPDKFVA
ALRSAASKEEVREIGMATCLELCRTLLDAGAPGLQFFTQNRSKATREILAELKHLS
>A0A6I6XTH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKDELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEADLGNFVHKVKAGADSAITQYFFNADSYFY
FVERAQKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLAIWNNLKLPR
>A0A0D2H602|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fonsecaea pedrosoi CBS 271.37|TrEMBL
MASEHDDRLPTLLSTLQPSSYYFSLEFFPPKTSSGFSNLQARLARMATALRPLFVTVTWG
AGGSTATKSLELAEVCQRQIGLTTVLHLTCTNMKRHMIDEALEGAKEIGIRNILALRGDP
PREEYKDATSTDDSESGSGGSGTESNQEFTWAVDLVRYIRRKHGDYFAVGVAGYPEGHAD
ESHPEQGKQSVEHDLPYLAEKVAAGADFIMTQLTYDIAAYAAYEERLRGYTDQDGKRLFE
KIPIIPGLMPIQSYQIIKRITKLSHARLPEDISQRIERVKSDDEAVKKVGVDILSELVEE
MKTLTQPEGLPRGFHFYTLNLEKSVSFILERTGLIPTISSEGSVEDKDGDSASDSDVVVE
DSKHSTPAIVTTGPGEDRHEEQPSGLVRRRRSSVNAQPHNRVITDRRSEPRTESRRPDSD
SDPPGLGPNPNLKLTSQHLATDRGTGIPAASPTRQHSLLISEGQGSLGREATWDDFPNGR
WGPSHSPAFGEIDGYGPSLKVSPLMARKLWGYPRSRQDVTELFRRHVLGELAAVPWSDDI
DPDLVSPGEGSADGSTNSSALRAETDVIRAELISLISRQNYWTLASQPAVDGAPSSDPVF
GWGPPGEGFVFQKAFVEFFCGRDEWEDKLRPRLMKHGSDVLGWMKTDAEGLFESSELVAR
DQARNQKTRAAADTEKENSKPASVSPGADQKVATSTSTSSPTNTVNAVTWGVFPSREILT
PTIIEAESFRAWAQEAYAIWHEWKRCFPRGSPESVFLEKMGKDNVLVNVVGQGFRGGHNG
GKGEGGRLWRILLGEDGDDKT
>A0A7W2KZB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKSALRDKTFVCVMEFVPKPSAQRFAAMEAIMARGHLCGWPMSLAVGDRVSSPLDLS
PLDALSSFSSPFPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYREEEGGAQYFKAEKKLAAGADFLTLQLGF
DANKHQEAMHWMSRQATPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAVSK
AYAQARSVDRLALQIMGVRLMGYAGVHLSGVHALNQLLDLEARLEYWQARIHSMQQWAPA
WAESWQMPGLPAVSFHPPQAAWRQGESTVRASSREKLRYHLLHGFHGLLFSRGNWLSQAF
GWAVRRPLWATARGARLLHGLERSVKRPLLGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTELNRCEFGDRECIHSVKYRTAKAVQQTTVLSERLIPCIEEQSRHRSSWPQWFEAQAP
HRLSPQPAPRTQPES
>A0A1H2FJL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula phenolica|TrEMBL
MNELKSGSEFKPGNDLKSGSNLEKVLKAGYFAFTGECGPPKGANVRHLKEKFQYLKGNVD
AVNMTDNQTAVVRMSSLAGSALLVEEGLEPNFQMVCRDRNRLAIMSDILGAYALGIRNML
CLSGDHQTFGNHPEAKNVHDIDSMQLISVVKKMRDEEKFINGEEIDVAPRMFIGAACNPF
ADPYEYRVYRLANKIEAGADFIQTQCIFNMEKFRDFMKKAVDMGLHERCYILAGVTPMKN
AGMANFMSKFVPGMDIPDSLIKRLKGVDKRDQAEEGIKFALEQVEEFKQMEGVSGVHMMA
IEWEHKMPEIAERAGMLPRPAV
>A0A6S6U1S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Thiotrichaceae bacterium|TrEMBL
GRLERVLRAGKFAVTTEIAPPDSADPQDVYDRAAVFDGYVDAMNATDGSGAHCHMSSVGM
CSLLTRRGYSMVMQVSCRDRNRIAIQGDVLGGAAMGVANILCLSGDGVQCGDHPEAKPVF
DLDCMSAMETIRTMRDKYQFLSGRKITSAPHVFLGAAANPFAEPFDYRPYRLAKKIEAGA
QFIQTQYCYDIDMLKTYMSKVRDLGLHEKVFLLVGVGPLASAKTAEWIRKNVAGVHIPDA
VIKRLSGAENQKQEGVNLCVDMINQVKEIEGVHGVHIMAYRQEHNVPEIVERSGVLGGRT
PWHPGLVESSSDQTWL
>A0A3A4P4X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Abyssubacteria bacterium SURF_5|TrEMBL
MKSGSNLEKVLAAGHFAVTAELGPPMGCNMEPVRKKIELLRGTADAYNVTDCQTAVVRMS
SIATSILLVREGLEPVMQMTCRDRNRIAIQSDILGAAGHGIHNCLCIAGDHQSFGAAGKL
KGHPGAKNVYDVDSIQLVGILKQLRDDSRQQGGDALDGPVPLFIGAAWTPLGDPIQIRTT
RLAKKIRAGADFIQTQAVYDIEQFAEAMRKARDKGLHERAAILAGIIVPKSAAMLTYMNK
SVPGVIVPQHLIDRMQAAADRRAEGIRIATELIEQVRRIEGVRGVHIQAIEWEAAVRDVV
GGAGLLPRPVV
>A0A0D2GQY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fonsecaea pedrosoi CBS 271.37|TrEMBL
MHVSKKLELAHQQKKPTFSFEFFPPKTAQGVQNLYDRMDRMHNLGPTFIDITWGAGGRHS
QLTSEMVNATQNYYGLETCMHLTCTDMERHQVDEALRRAYKTGCTNILALRGDPPRDQEK
WEAKDGGFRYAKDLVKYIKTRYGDHFDIGVAGYPEGCDDQRDVDVLIDHLKEKVDAGASF
VITQMFYDVDIFLNWVKKCRDRGITVPILPGIMPVQTYAAFVRRANWTKCHVPPEWFEAL
EPVKNDDAAVRAIGKDLVADMCRKILDFGIQHLHFYTMNLAQATRMVLEDLSLTPETSGT
RLEKPLPWRQSLGFNRRDETVRPIFWRNRNASYISRTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANIKLWGKPRSLRDVTSLFVRFLQGDLERLPWSEGAISSEADIIKDDLL
QLNTRGFLTINSQPAVDGASSTHPIYGWGPAGGWVYQKAYLELLVFPSMFKTVMGRLNAD
KNLTYYAVNRKGELYTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WAKCYPAGSGSRKLIEKIIDECYLVNIVNNDFHQNKEIFKVFEGLETKDLDLVIEDTVPS
SVENGTEDVPNGDASLGDVEKGLANGEQPKAPSKADADVLSN
>A0A1Z9D4W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium TMED115|TrEMBL
MTTETLASAVRGFSIESVPQDADRIDDFRDHVPTGTRVFIAWPPRATPESIVKSARKLHE
QEMVPVPHIAARRVPSQEFLRAFVGDLVAQAHVREVLVIGGDPATPEGPYTDTGSLLRSG
VLNELGIEKVGVAAHPEGHPVMSGAVSREVLADNLAAARDHGMSVEAVSQFVLDPQAIDS
WHAEVYSSLAQGAPLLIGIPGLVSGTRLLKIANACGIGESIGLLRKNGLRMAKTVIGNSS
TQTLVEGLAPLANRATDVGGFHFYTFGNFEQTAAWACEAASTPAAAAG
>A0A1H2E2T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula phenolica|TrEMBL
MSELKSGSNLEKVLNAGHFAFTGECGPPKGANVDHLNEKLSHLVGYVDAVNMTDNQTAVV
RMSSIAGSVLMMEKGLEPNFQMVCRDRNRLAMMSDILGAYAMGIRNMLCLSGDHTSFGNH
PEAKGVHDIDSMQLIAMVKKMRDEGKFLNGEDIDVPPKLFIGAAANPFADPYEYRVFRLA
NKIKAGVDFVQTQCIFNMEKFRDFMKQAVDMGLHEKCYILAGVTPMKSAPMANFMSKFVP
GMDIPEHLIKRLRGVPKKDQPEEGIKFALEQIEEFKEMEGVAGVHLMAIEWEHRVPEIAE
RANVLPRPVVE
>A0A1P8YGZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. MTM3W5.2|TrEMBL
MTQTPSIVDRIGSSGGRIPFSVEFSPPRDADAEARLWRAVREFEQMQPAFVSMTYGAGGS
TRDRTVRVTGALAEETTLLPVAHLTAVGHSVDELRAMVGAYADRGISNILVLRGDPPGDP
LGEWVRHPEGVEYAEELVRLVRDLGDFHVGVASFPEGHFRAPDLDHDTRYLVSKLRAGAE
YSITQMFFDVEDYLRLRDRVSRYDVEQGAKPIIPEIMPITSLRSVKRMVELSGSQLPREL
SERLDRAAGHGPEENRAAVREIGIELATEMSERLIAEGAPCLHFITLNFARATREVLARL
GLATSVR
>A0A543DXQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia kunmingensis|TrEMBL
MKVTQRIRGDRPVFSVEFFPPKDEAGEAELWRAIRRLEPLDPAFVSVTYGAGGSSRDRTI
RTTARIATDTTLVPMAHLTAVSHSVAELRQVIGAYAAAGIPNVLAVRGDPPGDPLGEWVA
HPEGLTYADELVRLVRRLGDFCVGVAAFPYGHPRSPGPEADLARLVAKVRAGADFAISQL
FLEPEGFLRLRDRMAAAGCEVPLLPGIMPLTTVRTLRRGPELSGAPLPPALVERMERYSD
DPTAFRAAGMDVTAEMCSRLLEEGVRGLHFYTLNRSTATVELVRRLGLGARRDELVDAAP
VGG
>A0A1Q9R1E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MTQERRYSFEFFPTKTDAGHEKLLATARTLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKEDLRALLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETADQFHIEIAAYPEMHPQAHNFEDDLANFVRKAKAGADSAITQYFFNAESYFY
FVERVQKLGVKIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDAKSIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7G7KI63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. HK01-R|TrEMBL
MTSALQRILAQGGGPALTAEVMPPRGGDPSHALAMAERLRDRVHAINVTDGSRAVMRMSS
LALCRLLLDAGHEPVLQIACRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAGDQSAAR
PVNELEAVRLLQQVSAFNRGEDPVEGALADGPTALFAGAAADPHSASWSGLARRLERKRM
AGAAFVQTQMVMDPEALERFCRELADPLELPVLAGVFLLKSARNAQFINRMVPGACIPES
LIERLAQAQDPAAEGVKIAAEQVHRYLGIAQGVHLMAVKAEQRIPEILECAGISSLPG
>A0A6A7A1M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiobolus disseminans|TrEMBL
MERITDKINALPDGSNYFSLEFFPPKTSMGFANLTTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRALIDEALEQAKVLGIRNILALRGDAPRSEE
YRDQDQSPEQDSNKDFTWAIDLVKYIRKQYGDYFCIGVAAYPEGHSDESHPEHQDPKFDL
PYLIEKTKAGADFLMTQLFYDVDAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHARLPPDILARLDAVKNDDELVKQVGVKVLDEMVEHIKARPDVRRRGFHFYTLNL
EKAVSHIIVDCNLIPKEAMQDEVVIVETTPAINLEPPPHGALNGDRRRLSSTYSGPRNKV
IVSHPSATKSSNHSYEATEEEAGIPRGPVNTRANTLAISEGEGSMGREATWDDYPNGRWG
DARSPAFGEIDGYGPTLHVSSQQALKLWGHPVESKDISTLFKRHIDGELEALPWSEQGLS
PETSTIAKQILALNAKGWWTVASQPAVNGVKSTDPVFGWGPKNGYVFQKPFVEFFVPASQ
FEALKSRLDAHEQVTYFAGNDAGDFEASNEESVNPVTWGTFAGKEIVTPTIIEAVSFRSW
LEEAFSIWREWERIYPPRSASSKLLSDTRRDVWLVNVIWGDFVQGEGLWEFLGA
>A0A847D613|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus flocculiformis|TrEMBL
MKIESKFQKKKPVLSFEIFPPKRDKAIQNIDETLAILSELNPDFISVTFGAGGSHTDNQT
VELAKRIKQQYGIDPLVHLTCLNSSKFEICELLEELKEAEIDRILALRGDKNPAVEEKQD
FRYASDLVKFIRQYGDFSISGACYPECHTESKNKIEDIAYLKEKVDSGVQHLISQLFFDN
NAFYSFQEHIQIAGMHVPVEAGIMPVINKAQIERMVTFCGASLPEKFSRVMHKYEDNKEA
LFDAGMAYAINQIVDLLAHDVDGIHIYTMNNPIVAKRICDGIKNLI
>Q8TKA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRYSVPLEDARHLKGRADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDFPSCGDHPGSKP
VYDLDSVQLIELVRKLDSGFDLAGNILDGGTSFCAGAVSGIDPDKIIQLIKLEKKVRGGA
DFIQTQAVYDVGIFEEFMEAVNHLEVPIIAGLIPLKSLGMAEYMNKNISGIHVPDEIMLR
MKEASSPLEEGLLIASETIKELTKLSRGVHIMPIGSHKNTPRLLSMAGISEI
>A0A8J3ARI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalicibacterium faecigallinarum|TrEMBL
MQVPVASLPKISFEFFPPKTPAGVGKLHATSATLAAWQPEFFSVTFGAGGSTQAGTRDTV
FALQAAGYEAAPHLSCIGSSAEQLRIILDAYKTQGIRRLVALRGDLPSGYGGKSAGQFRY
ANELVSFIRAETGDWFNIEVAAYPEMHPQAPSPDDDVANFVRKANAGANAAITQVFYNTD
AYFRFVDEVRKAGSDIPIVPGILPITNYAQLIRFTETCGAEVPRWMQRKLASFHDDTASL
CAFGTDVVTEICDRLIAGGAPGLHFYTMNQSAPTLAILNALRPDITHGSLVAVAA
>A0A5B8B292|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 8|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKTDEMETRLWETVTRLEPLKPNFVSVTYGAGGSTR
ERTARTVKRILDQSALPPAAHLTCIDADKESVDQVIRQFVDLGVTRFVALRGDPAAGVGT
RYQPHPGGYANGADMVAALKRHGDFDISVSAYPEKHPESPDFATDIEMLKRKVDNGATRA
ITQFFFDNDIYERYVERVRRAGIYIPIVPGILPVHNIRQVANFSARAGAHVPAWLSERFE
GLDDDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLAFAICHMIGIRSQPSERG
IGEAAGSAAA
>A0A0D0YLZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus gattii VGIV IND107|TrEMBL
MPHLTSLIATHNGPFHNYEFFPPLTDPGFVNLLDRIRRLTSPPFQAPLAVSVTWGAGGST
AERSLELAQQIVGMGVEVILHLTCTNMPKDKVDTALQRCKALGISNILALRGDPPREEEY
AINPTSTPDFFKHADDLVRYIRQTHGDYFCIGVAGYPNPHPDSETEEEDFKWFKAKCDAG
ADFIVTQLFYDVDVFSEWVKTCRAKGINQPIIPGIMPIQNYASFRRLVNLTKCPVPDSIT
SDLQPISSDDAAVKRYGAELATKMVNQIIESGLVPGVHFCTLNLEKSVRTILDNLGWSAT
SKTSANDGVVKNKLIQDDSRAVNGIQINGKAGKTQNPAEDLSISPSEANQLAQLGLTSTT
LPPAPKTGLSAQGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKEWGVP
VSTSDLSALFTAYLHSDPNHLTTPFCDLPLSPESHMILPHLLALNSAKVQHWTVGSQPAV
DAAKSEDGVVGWGPRGGYVFQKAFVEFFVTEDEVNRLTKKVEEEGKGLITMYAANRKGAF
RTNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWTEWSLLYPRNTPSRKL
LEGIANEWWLVSLIHHDYKDQDALWRFLLEDLQ
>A0A1S7SVG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium fabacearum CFBP 5771|TrEMBL
MHDISTSPAIAASIEASPAQVLGPASLAGIFPQGVRVYLTDTGQASQDRLVDAAKHLRDL
GYTPVPHLAARRISSRVEFEEQVKRLAGEAGVSDVLVVGGGVATPAGPFASSMDMLSTGI
FDRCGINQIAIAGHPEGSPDFSDETATAALKLKCDFAERSDAAMRIVTQFGFDPTRFIAW
AEGLAASGIDLPVHIGVSGPARITTLLKYAALCGVGNSIAYLKKNALSLTTLAKGHSPES
VVGPIERHWQANPAGPIRQIHVFPFGGLQNSADWLAGRGSWQTGDADFSTKRGTVAI
>A0A0M2EXV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium brasiliense|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWDSGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTTMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A2N2JD92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-14|TrEMBL
MASARTDHDYSTFREFLAGDGVAMFDGAMGTMLYQRGVFINRPFEELNLTQPAAVREVHE
AYLDAGADILETNTFAANRFRLSPHGLEEQVAEINRAGVEIAREVAGADAWVGGAMGPLG
VRIEPFGPIGKGEAREVFAEQALALAEAGVDLFVLETFAHLPELVEAVHAVRSVSDLPIV
AQVAVGAGGVTREGVKSADAAAALTTAGADVVGVNCSDALSALASLHGMRSATDLPLSCQ
PNAGAPKDVEGRKIYLGSPDYFVAWGRRAIRQGARLLGGCCGTTPDHIRALCTVVGEAAP
VVDAREVARALDRAPVAEPVPTREKSVLAAALQDGRFVTVVEVPPVRGWETADAIRAARK
LALSGVTAVAIPEGAAAVAHLPPFAQAEALRTVGMGTIIQYSARGRRLMRMQSDLLGAAT
MGVANLLLVTGDPLVPGAERDAWPELEVDSIGLVNLVTRLNHGEDVGGNPIGRPTEFHIG
VHLDPTAFDPERERSRFFWKVDAGAEYALTAPIFDAAALTRCVAGLRTPGDKHIPVIATI
WPLSSASQAELFEHRRSSVAVPAALVERMRRAEAAGTEEAEGLAIARELALAVRPHVQGL
QVVAPNGRVDLALAVLEGLT
>A0A0M5KW64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIANTIH
GEYGIPAVAHLTALYSDEAKIDEALDMFEAAGVSAVLALRGDYIDGEEPVGRFNHASDLA
AYIHDRKPDLKVFGACYPEGHYSAASLDEDIGNLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGAKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGII
YASDQIADLVAHGVDGVHLYSMNHPATTRRIWHNVEPLFTVE
>A0A837L3S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIANTIH
GEYGIPAVAHLTALYSDEAKIDEALDMFEAAGVSAVLALRGDYIDGEEPVGRFNHASDLA
TYIHDRKPGLKVFGACYPEGHYSAASLDEDIGNLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAASIDVPIEAGIMPVRGAKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGII
YASDQIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFTVE
>A0A101A6W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium lehmannii|TrEMBL
MEFGPCGGVRPDGQCEMRPGPCTFADVVPWSGPRREPRPVRAPLVLTDFSNAAFDARDVA
ATAGLLAPSCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDRNRVVLEQELRG
LLSIGVDTALCVTGDGRGYDVRPDVTQTFDLDGPRLVELAASIGMVAAVPETPTAPPIPG
RPTRLVEKQRAGASLAVLNHVPFPAMIADFMQSARAAGLSIPVIAAVAVFTDSVSAAVLQ
GLPGLELDPSVTEYVLGAADPVAAGIEAAVAEAEALLSIDGVEGVNVSGLASASGARVGA
EIKAEVGRRIQEVAA
>A0A1G8EWA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio xiamenensis|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAQTGLVATPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPPGGGAPAMYASDLVELLKSRHNFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMARQFE
GLDDDPTTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPKA
>A0A2G1LL72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. IP1|TrEMBL
MTQTDRARHHAEGPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFVSVTY
GAGGSTRERTHNTVARIARETPLAAAAHLTCVAASKAEIDEVADAYWEAGVRHIVALRGD
PPEAGTAFQPHPDGYKGAAELVEGLRKRHDFEISVAAYPETHPDALSAQSDIDNLKRKID
AGATRAITQFFFEADTFFRFRDTVAAAGIDADVIPGIMPVSNFAAVQRMSAMCNTDVPAW
MGRLFDGLDQHPAARQLVSATLAAELCRNLYMGGVRDFHFYTLNRAELSYAICHLLGLRP
QVAAELEKTA
>A0A2A9F7F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sulphurea|TrEMBL
MTSVIERLQGDAPPFSIEFFPPRDEADEAVLWRSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLCPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPEGLTYAEELVELVRSLGDFCVGVSAFPYGHPRSADLETDTKYLVRKFRAGADFAIAQ
LFFEAEDFLRLRDRVAAAGCDALVLPGIMPLTTPRTLRTTIKLSGTSASQRLLDRLEPLS
DDPKAFRAAGLDAVTEMCEKLLAEGVPDLHFYTFNRAKATREVVTRLGLVPARA
>A0A1G9FRQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus chinensis|TrEMBL
MTTPSVSFEFFPPKNLDQSFKLWETANALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
NYGLNVAAHLTCVDASREETMRIVDDYAKAGVREIVALRGDPPQGSERFAPHPEGFADSV
ELIEAIAARGGFTIRCGAYPEPHPDSPDTAADVVWLKRKVDAGASSAITQFFFDADVYFR
FRDACDRAGVAAPIIPGILPIQSWSGARKFAARCGASVPAWADAAFAKAGPEGERALAVD
MAVTLCRRLIEGGVDRLHFYTVNRPQMTLAVCEGLGIALRQAKVA
>F3MAZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. HGF5|TrEMBL
MKPNLRQAWENQVLVGDGAMGTYLYQKGFPVGISYEELNLTSPEVIGNVHRQYVEAGAQV
IETNTFSANYDKLSKYGLEARAGEINRAGVRIAREAAGDHGYVVGAVGSIRAGKRSNIST
SELKRYFEEQLSVLIAEGVDGILLETFYDVDEMQLALAQARMLSDLPVICQFAVEDIART
LDGFTMPDAYRILSQEGADVIGFNCRTGPNGIMRALETLNGIMNLPASVYPNAGIADYVD
GEYRYGASPEYFGKTALEFADRGARIIGGCCGTTPEHIAEISSALSGYVPSPLPAVEEAE
INRIVIHETAQEQFYERSGEPTIVDIVKERHTVIVELDPPRDLDITKFMKGAEALKKAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVVGAAFNP
NVRHLDKAVARLEKKIASGADYVMTQPVYDPELMVRLREATAHLDIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAMGVKIGKELLDVATEHFNGIYLMTPFMFY
EMSVQLMEYVWEKSGRRLTPLFH
>A0A834AF80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllostomus discolor|TrEMBL
MVNEPRGNSGPGAHWEGSSCGIENSKDSLKGSSPGLDPERRERLREKMKRKMESGDKWFS
LEFFPPRMAQGAVNLIAMFDQMGAGGPLFIDVTWRPTQDPGSDKETSSMTIASTAVNYCG
LETMLHMTCLCQSREAVTGHLRKARRLGLKNILALRGDPPGEQWEEEEGEFSHATDLVKH
IRSEFGDYFDICVAGYPKGHPDAVSFEDDLKHLKEKVTAGADFIITQLFFEADTFFLFVD
ACSKIGITCPILPGIFLIQSYHSLRQLMKLSKLEVPQSIRDVIEPIKDNDDAICNYGIDQ
AVSLCRKLLASGLVPGLHFYTLNRLKATTEVLKRLGMWTEEPRRPLPWALSAHPKRREED
VRPIFWASRPKSYIYRTRDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKAPREELLKMW
GEQLSSEKSVFDVFVRYLSGEPNQNGHPVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPRVNGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLRVLKKYELRVNYHIV
DVKTDTRT
>W4M3Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Entotheonella gemina|TrEMBL
MNRDTFKQRLENGPLLLDGAMGTLLYGKGISIDQCFDALNRREPQAVAGIYRDYIDAGVD
VLETNTFASNRYKLAEYGLQHEVLELNTAAVSIARRVIDASFSSKPVLLAGAIGPLGVRL
APLGRVRVPEAKAAFREQIQALVGADPKGVDLLILETMADLKEVEAAVDVAREVAPELPI
VAQMAFTHDDRTFIGHTPDEAARKLSGFDVDMIGVNCSSGPAQVLRLISIMKEVAPDMPI
AAVPNAGWPEQTEGGRVMYAATPEYFARYTQAFCEVGAGLIGGCCGTTDLHIAAMRQALD
TPGENTISLPRVKFLQRDTAVTAVVEQPTQLAQYLNEGTFVITVEMSPPKGVGAERLLRR
ASMLKEAGANILNLADSPLARMRMSAWAAAYLVQQDVGLETILHFPTRGRNLLRIQGDLL
AAHDMGIRNLFVAMGDPTRIGDFPEAMDSYDIVPTGLMQLITQQFNAGVDKSGNRIDQAT
SFVAGCALSLTPKDVEREMILLRKKVRNGAGFALTQPVFDAAAARNFINTYETRYGEPII
PILAGIKLLHNGRNADFLHNEVPGMIIPEAYRQRMHAADNPQQTGVRIAQEMMEEIRPFV
QGVYFMPNFGRYDLVADVIGGQR
>A0A4U0R8V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus hibiscisoli|TrEMBL
MTDDAPPPDFARWQPSYDTPPPGHVSGSRLERVLRQGHFAVTAELNPPDSADPADVFTAA
RPLAEVADAINATDASGANCHMSSIGISALLTRAGYGTVYQISCRDRNRIAIQGDVLGAA
AMGVRNVLCLTGDGVGVGDQPGARPVFDLDSISLLRTIRTMRDDGVFLSGRRITSPPRMF
LGAAENPCIAPLDWRPDRLAKKVEAGADFIQTNYIFDIPVFARFMARVRDLGLDRRVFIL
AGVGPLASGRAARWMRSNVPGIHIPDAVIDRLDRAADPGEEGKRLCIELIQQIRQIAGVS
GVHVMAYRREHLVREIIAQSGVCRDRARA
>A0A4V2MAE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella pittospori|TrEMBL
MPGFEVVCEVEPPTRPDLKRVRHQIGVMSPIADAFLIPDNHIGRATVSSVAVANEVQAMG
SRGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDDPAEGARTSQLTVRTMIEQARE
TSYPGCNQFQVGAATRLRAVPRWKAEADFLYVQVSYDLDELLRWRDSVSLDIPVYAGVMV
LASAKMAHNLAALPQLTIPETLIDAVERDQDAGVDHACELILSIRDSGAFDGVHLIPVSR
YRQVAARLEREL
>A0A1Z8N3E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium TMED10|TrEMBL
MKIGEVYADGRFGLSFELFPPKTPAGEKALFEHXNRXIEFSPSXITCTYGAGGSTQAKTL
DIIDRVQXXYAXMVASHLTCVGLSRNEXXHYLQEADKRNISNIVALRGDPPQGADSFEPP
EDGLRYASELVTLICDAFPEFGIAVAGYPETHREAESPEADLENLQRKVELGGDLVITQL
FYDNADFFRFQELCKVRGIQVPIVPGILPVTNLAQIQRISGLCGATLPPAFEAALKQCED
DEEKQFEVGVRFAIEQVTELIDHGVPGIHFYVLNKSNATARILESVKVPARI
>A0A4U0XU68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Friedmanniomyces simplex|TrEMBL
MDKITDKLAALPPDSQYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKALGVRNILALRGDPPRSDE
YRDDGNPEAEADDSNKDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPYLVEKASAGADFIMTQLFYDVDAYTRYERRLREHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHAALPPNVLKRLEAVKGDDEAVKRVGVDIITEAVETMKAIPNPALESHTACDA
SHHRPDSNGIPDQAIAEEEKDGFLIVEKSKQNGNRRRDSSARNSQPRNRVVVSRDRASST
SSNRTSAFEAPEDEAGVPRDQINSRANTLAISQGEGAVGREATWDDFPNGRWGDVRSPAY
GEIDGYGVSLHASIPEANRLWGQPRSIEDISTILRNHLEGKIDAIPWSEEALQAETLTIK
EQLLGLVEKGWWSVASQPAVNGKRSNDPVFGWGPKNGFVFQKPFVELFLPAADWERLRPG
LDADEQVTYFAGNAAGDFVSTDEQSVNPVTWGTFTGKEIITPTIIEAVSFKSWMEEAFGI
WAEWQRVYKPGSESSRLLERVRKGYWLVNIIHHGYLEEHALWERLLRA
>A0A482YSF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium endosymbiont of Bathymodiolus sp. 5 South|TrEMBL
MKTSFEFFPPRTEKGKQTLHQVRQELSSLNPEYFSVTFGALGTTQEVTLETVLDIQKNDT
VAAAPHLSCIGSKKEIIIELLDQYKAANINRLVALRGDIPSGVRDIGDFHYANELVEFVK
SQYNHHFHIEIAAYPEMHPESKNRLTDLQHFADKVKAGADGAITQYFYDADAYFKFVDAT
EKLGINIPITPGIMPITNYTQLVRFSKMCGAKIPHWILKKLELYQDDFDSLSAFGLEVVT
NLCQTLKAQGVNNFHFYSMNRSQPSLEIAKHL
>A0A2W6D314|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIDEIIATSQEPVFSFEFFPPKTEEGERNLRSALEELRALAPDFASVTYGAGGSTRDRT
LEVTKWLKQELGIEAMAHLSCVGCTREELGAILDGIAAAGIENVLALRGDPPRGQVEWQP
HPGGLRYSTELAALISDDYPAFSVGAACFPEVHPEADGLEQDLRFLKEKVHSGASFLITQ
LFFDNELYFRFVQEA
>A0A4Y7BGN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramlibacter sp. WS9|TrEMBL
MNLPISLEFFPPKTPEGAAKLRTARQALYELKPEFCSVTYGAGGSTQEGTFGTVKEILAE
GVDAAAHFSCVGATRDTVREQLVILRNMGVKRLVALRGDLPSGYGAGGEFHYASDLVAFI
RAETGSDFHLEVACYPEVHPQARSPEADLQAYAAKIRAGADAAITQYFYNADSYFRFVEE
ADRLGLHVPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSYGDDVASIKSFGLDVV
TQLCEQLMAGGVPGIHFYTMNQAAATMEICKRLGHSA
>A0A1I9Y462|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. 1_2014MBL_MicDiv|TrEMBL
MIDPDKPRPASNIAHAYSLEVSAKDMPALSAAASRIVPASTIAIPYLPREDNDARLAAAR
AVRGLGFEPMPHFSARRIASLAAFESFVQRAVAEAGVERCFVIAGDPSTPMGPFSDSGAL
IDTGVFERAGIKVIGVGGHPEGHPVMNTAAQWEVLERKCRSIDERGMTPLIVTQFAFDAD
IVLTWLQALRARGIAHPVRVGVPGPASIAVLARYAALCGVSACASMWSKYGVSIGKLFGT
AGPDLFVERLAAGLTTAHGQVSLHFFPFGGIAQSVKWIEQYRSRIAPAP
>A0A4R6TFE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum caenipelagi|TrEMBL
MKVTEHIQNANGTSLFSFEILPPLKGDTIDSIFKNIDPLMEFNPPFIDVTYHREEYVYKE
LENGLLKKQVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPEKEGHAYASELVTQIESLNKGRYLDDDLQNSSKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKNGASYVVTQMFFDNQKYFEFVEKCREAGITVPIIPGLK
PISTKKQLNLIPHRFKVDLPDTLVKEVVNCKDNSEVRQVGVEWCIAQSKELQQKGVPILH
YYSMGRSTNIQQIAEAVF
>A0A1I1B8C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium frigidicarnis|TrEMBL
MRISNLFKEKELVFSFEIFPPKVTSPIETIYDTLEGLKDLKPDYISVTYGAAGSSPGNKI
CELSSLIKNKYDIEPLAHLTCINSNKDFIKNILDELKENNVENILALRGDVLGETKISKD
FNNACKLIEYIKKNKGFGISAACYPEGHIESKNLKEDIEVLKVKVESGAEHLISQLFFDN
NCFYNFLDKVEQKGLNVPIQAGIMPVTNKKQIERIVSLCGSNVPLKFIKIMEKYEHDKEA
LRDAGIAYAMDQIVDLISTGVRGIHLYTMNNPYIARKINENISSVINSINRKQVS
>A0A7T4DLE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium casei|TrEMBL
MSTSLTHPDPVLDSSFRDVDRRPPIDHRPPRPHPDADATVREPRASASAPVSLPHPEPDS
ERHHPLALSFEVMPPRSAAQAAGTPELLALLDELHPDYLAVTSSAKSNWLHGTADFIRII
SETTQLRPLAHLACTAGTADELRGWIRHLLSAGVRGFLAIRGDFPTGTDRVPAGHLPHAD
ALVHLLRTIEAEHTAKLAAGRLGIGVAAYPSGHAQSSGPDEDLDVLAAKQRLGADFAITQ
LFFDPGHFARLRRRADLAGITMPIIPGILPITDIRRLHTMSRLAELPVPDHLLARFDGAA
SPQAQRRIGLEMTAEHVATILDQGAAGLHFYTFNDRTTTIDLLGALDRLGVSLHPTPVPA
L
>A0A1W1WWA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratiruptor tergarcus DSM 16512|TrEMBL
MFEELIEKLRSGTYITLETTPGHLPTINNILSKLDEFALYKKVDAFTTTDNPLAKLKYNA
ILAAIKLQQRFNKPVIATMSMRDRNKIALQSDLLGANDFDIRAILALTGDPAKISDQPNT
KGCFEGDSTLLLDIIRFFNAGIDYAGKEFKIKPKRIYPFAVSNAYAKNPNTLLKKFKKKI
EHGAVGVITQPVFDIENLKNLLTLFEEARNNFENERAKSELIVGFFPITRLKTAQFLASH
VPGINVPRSWIDELYKAHKDGEEKEYEVGFALSKELFTNIMALHPKVHIMTANRFDLAHA
ILS
>A0A7V1HUR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaeraceae bacterium|TrEMBL
MHITDVLANHATTFSFEFFPPRENSAWDGLFERIAELESLKPSFVSVTYGAGGSTRTRTH
ELVERIKRETTLDVTPHLTCIGHSPRDVDEILERYARAGVSNILALRGDPPRGQGEPEEI
GGFPHAADLVKHIRNFTGHKDVRGFGIGVAGFPEGHPGTPNRLLEMDYLRAKVDQGADYI
CTQLFFDNRDFFDFRDRCELSGIRIPIIAGIMPITSIAGARRISELALGARIPAPLVRSL
TRVQDDP
>A0A7C9KUY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospira eligens|TrEMBL
MKYTGTAGILYDRLKSEILVADGAFGTYYAKKYDTGSLPELANLQASDRVLAIHKEYIEA
GAKIIRTNTFASNTVCLGAGFDEVRNNIKNAVDIAREAVKGTDVLVAADIGPIPGENMIE
KEHIEKEYVDIVNVFKECGVDIFVFETFPELGFIDKAIENAGENGFVITQFAINQFGYSS
AGFSARKLIEEAEKNSYIDACGFNCGVGPGHMKKLVQSLINRNDKYFAVLPNAGYPQVVS
GRMVFDDNNAAYFSQIMHDLAEDGADIIGGCCGTTPEYIRQMVLKTADVVHMKNASIEEE
ISEKKTANDVSFYKGKEGRKLIAVELAPPLGIDDEKIMDAAFLMKESGVDVLTFPDSPSG
RTRADSILMAEKVSRETGMCVMPHICCRDKNAIAMRSQLLGAHINDINNFLVITGDPIPS
VVRASVKSVFNFDSVGLMNIISDMNQEQFAGKPVIYGGAINQGRVNFKVELERVKKKMEA
GATFFMTQPVFSDEDIDRLRQIKEQTGARILCGIMPFVSLRNATFMKNEMTGINVTDEIL
SRYRADMSKEEGEETGIQIAREIIAKTTDFVDGYYFSFPFNRVHMLKKIIGKNNQ
>A0A674AP94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmo trutta|TrEMBL
MIIATPRGEIFDSSGKRNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTESGDHWFSL
EFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGL
ESILHLTCCNQTKETITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKHI
RCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRTDTFLKFVRD
CRAIGITCPILPGIFPIQGYQSLKQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGIEQT
VGMCRVLLESGNVLGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDV
RPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWG
EELTSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMMDKLDKVNRRGVLTI
NSQPTINGMPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPRVNYHIVN
VHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDE
SPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDNMFEPQMCMCLLKRSETDSMRVV
>A0A7X9L9U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium sp|TrEMBL
YFRMVERVRAIGCTLPIVAGIQPVTNLAQISRFAALSGAELPERVVRRLHEVGDDPAAVR
RVGVEIATELSAELLRGGAPGLQFFTLNRSRATAAILANLRRLGLDRRTPAAVSDG
>A0A840PY91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ureibacillus thermosphaericus|TrEMBL
MGLLDALKHKVLVADGAMGTLLYSYGLENCHEEMNIEKPEIIKKIHKEYIQAGADVIQTN
TYGANRIKLTRYGLESKVVEINEGAIDIAKQAAKNSEVFILGSIGGIRGVRKVDYTLDEI
LAAVREQAEVLIAGQLDGLLLETYYDFEELCETLKMLRAMTDMPIIAQVSMQEPGVLMNG
MKLNEALKQLEKLGADIVGVNCRLGPYHTIQAFEQVEIPERAYLSVYPNASLLDIEEGRV
VYESEVDYFARAAVELCNEGVRLIGGCCGTTPKHIEAMKKKLAHFQPVEKKEAKPQREII
IREAEPHSFEPLHEKAKRARSVIVELDTPKHLEIEQFVEGAKALYNAGADLIMMADNSLA
SPRVSNLAMGAILKLQYGIRTMPHITCRDRNLIGLQSHLMGLNALGLHDVLAVTGDPTKV
GDFPGATSVYDVSSMELISLIKQLNEGISFSGKALRKKANFSVAAAFNPNVRVLDRAVSR
LEKKIEHGADYFITQPVYSKEKIVEIHEATKHLDTPIYIGIMPLTSFKNAEFLHHEVPGI
KLSDDVLERMQQVSGNKEQETKVGLEIAKELLDTATKYFNGIYLITPFMRYEITLQLLQY
IQQLDEQNKGVKANG
>A0A7S2Y439|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amphiprora paludosa|TrEMBL
GGGSLGSTAVQSMAVASHTQKFLGVDALLHVTAQGVGAQDLKRHLHQAKLSGIQNLLVLR
GDPPRGKRSWLPGDVSGGDFPRAIDLVKFIRQEYGDYFGLAVAGHPEGHPSSASIQQEIQ
HLKDKVEAGADFVVTQFVYDADKLLQYVRLCRDEGISCPIIPGIMPIQSYNSFLRMTEYC
SVSIPDHILDRLSPVRNDDQAVKEIGVEVAVDMCRRILKESNGEVEGVHFYTLNLERSVT
NVLLKMGALDWTGSEQGDAENLVAEQRRNRSPSLSEIESRSGRVLPWRPSAMQGRSQTEE
VRPINWANRPKSYVQRTEDWDEFPNG
>A0A3F3GBK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera sp. 28|TrEMBL
MNTELSIEFFPPQTAEGAHKLRATCAQLAALEPAFFSVTYGAGGSTRERTFSAVKEIAAA
GHEAAPHLSCIGSTRDSIRDILQEYADAGIRRIVALRGDLPSGAGAAGEFRYANELVEFI
RAETGDRFSIEVAAYPEWHPQAKSPKDDLAAFKRKVDAGANSAITQFFYNPDAYLNFVEA
ARKMGITIPIVPGIMPIVSFSKLARFADACGAEIPRWMRKSFESYGDDSESIRALGLDVV
TRLCERLIAEGVPGLHFYSMNMAGPTIEICTRLGRSLRQD
>A0A0F5P787|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. SRS2|TrEMBL
MTSVPYSQLEEARRALDAPLFADLAGDAAVSFEFFPPKSDKMEETLWSAIQTLSPLKPRF
VSVTYGAGGSTRERTHHTVARIATETTIPAAAHLTCVEASKAEIDDIARAYWAAGVRHIV
ALRGDPPTEGASFVPHPDGYRNAADLVAGLKDIHPFEISVAAYPECHPEAVSAEADIANL
KAKFDAGATRAITQFFFSPEAYFRFCDRARAAGIDGEIVPGILPVSNVAQTRKFAGMCGA
AIPAWMDRLFEGLDDHPPARQLVAATIAAEMCRRLYAGGVRQFHFYTLNRAELSFAICHL
LGLRADGTALENAA
>A0A2D6B7L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibaca sp|TrEMBL
MQRPDISFEFFPPRNIEATFRLWDTVQSLAPLDPRXVSVTXGAGGTTRELTRDVVATLHK
HSGLKVAAHLTCVDATKSETLAIAEQFNAAGVSDIVALRGDPPKGATGFTPHEDGFSSSV
ELIEALREAGDFNIRVGAYPDIXPEAASGQADVDWLKRKLDAGASEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGILPIENWKGARRFAESCGTKIPAWVIEAFEKAERDGRQDLLAT
SICTELCSELLDGGVDKLHFYTLNRPELTRDVCFALGVTPETKLEHVA
>A0A1H6RTR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myroides marinus|TrEMBL
MKVTEHIQKANGKTQFSFEILPPLKGQNIQGIFDSIEPLMEFEPPFIDVTYHREEYEYKE
AGNGLWEKRVVRKRPGTVGICSAIQNRFKLDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKNETYFKPEPKGNKYASELVTQIAELNQGIYLDPELENTSKTDFCIGVAGY
PEKHMEAPNFDTDLKYLKQKIDNGAEYIVTQMFFDNSKFFEFVDKCRAIGIDVPIIPGLK
PLATLSQLNLLPQRFKVDLPDDLVAEVLKAKDNTAIREIGIEWCAQQSKELIAAGIPIVH
YYSMGKSDNIIKIIKKAI
>A0A4R6W8C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium yanglingense|TrEMBL
MKIIDHIKQADGKTLFSFELLPPAKGKGIQSIFNTMDKLMEFNPPFIDVTYHREDYLYKE
HANGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTPGGHAYATDLLKQVLDMNSGHYLHEDMESSEQTDFCVGVAGY
PEKHFESPNFNTDFKWLKKKVEMGADFIVTQMFYNIDKYKEFVVKCRDNGIHVPIIPGLK
PLTSKKQLIALPKIFHLDIPEELSDAVDACKTNADVQLVSQEWMVNMCKELIDFGAPVLH
FYTMSNPGPTQKIVEQLA
>A0A7W0BZX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus caldiproteolyticus|TrEMBL
MGLLEDLKERIVIADGAMGTLLYSHGADRCFEELNLSKPDDIIHIHEAYMAAGAEVIQTN
TYGANYIKLARYGLEDEVKTINRAAVKLAKQAAANHAYVLGTIGGLRSINKSSLTIEEIK
RTFREQLYVLLHEDIDGLLLETYYDLEELKTVLTIARKETDKPIIAHVTLHDVGVLQDGT
PLADAIVQLEQLGADVVGLNCHLGPYHMIRSLEEVPLPTTAFLSAYPNASLPDYRDGRLV
YETNAAYFEETALSFREQGVRLIGGCCGTTPKHIEAIARALKDRTPIHEKTVKPRRTVVS
IQEVEQENEPPLQEIVRKRHSVIVELDPPKKLGITKFLEGAKALKEVNIDALTLADNSLA
TPRISNMALGTIVKQQLGVRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAVTGDPSKI
GDFPGATSVYDLSSFDLIQLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVER
LEKKIRCGADYFISQPLYSEQQIEEVYEATKHLEAPIYIGIMPLTSARNADFLHHEVPGI
TLSEKIRSRMASCANNPIQSAREGIAIAKSLIDAAFDLFNGIYLITPFLRYEMTVELAHY
IHEKEQAAQEREVLHG
>E1Z340|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorella variabilis|TrEMBL
MTKIIDKLNGKIAEGKSFFSFEYFPPKTDEGVHNLKERQMRMAALGPCFCDITWGAGGST
AEVTLDVARSMQQEVGVETMMHLTCTNMPVEKLKEALTKAKEYGITNILALRGDPPKGQD
HFEVVEGGFSCALDLVKYIRAEHGDFFGIGVSGYPEAHPDVIVEDERQMRKNYWADIEYL
KQKMEAGADFVVTQLFYDCDRYLQFVKDCRSVGITAPILPGVMPIMTYGGFKRMTSFCKT
AVPQHIADTLETIKGSDEAAYGISLGTMMCQRLLASGAPGVHMYTLNLERSAGEALGWRR
AAPVPGCGQAPFLQLQGWRAASREASCR
>A0A2G5BB32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coemansia reversa (strain ATCC 12441 / NRRL 1564)|TrEMBL
MKVSDKLRQALASEKPFFSFEYFPPKTEQGLANLYDRIERMARLGPVFMAVTWGAGGATA
QRTLELCSACQGVFGVETVMHLTCTNMDKEMVDTALKGAKAAGIQNILALRGDTPRGEEY
WTACEGGFSYAVDLVRYIRSQYGDYFCIGVAGYPEGHTENPDSEKDFEYFKAKVEAGADF
VVSQLAYDAEVFVQWERKCREHGIMLPIVPGVLPIQSYQSFRRLAFLTRVSVPEELRERL
EEAKTNDQAVKDLGVEHAVAMVKRLQAAGIYGVHMTTLNLENSVQRVLAALEMGAGGPLS
PVARQATSTGSVVTAAAAAAAGGSTGAAEGVAQRRVWDDFPNGRWGDARSPAFGSIDAYG
AMLRFDSQGARRVWGRPQQLSDITDLFVGYVEGRIPSLPWSDEPLRAESQRLVTELTRIN
QLGYWTVASQPALDGVASADATHGWGPRGGYVYQKAFVECFVPRDLFGLFLSRLQSAAPR
ITYYAANKQGDFMTNAFSNNSESENASAATALTWGVFPGRAVVQPTLIDKMSFLAWRAEA
FQTWREWATMFPSDSPEMRFLTATADECWLVNVVDNDYKRPDAIWNMF
>A0A1G3AZQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RIFCSPHIGHO2_02_FULL_52_58|TrEMBL
MPVLTSGSHLERLLREGRFVVTAELGPPRGAERAVVEKKANLLNGYVDAVNITDCQTSVV
RMSSIASARILLEMGLEPVVQMTCRDRNRIALQSDLLGAWALGMKNLLCLTGDHPKFGDH
PGAKPVFDLDSIHLLHMLKTMREEKKMLSGTPLEGEPRFFLGAAENPFADPFAFRSRRLA
KKITAGAEFIQTQIVYNVDKFARWMEEVREKGLHKRAFILAGVAPL
>A0A2R4T063|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lunaelactis|TrEMBL
MALGTPSTRTDRARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVAPNFVSV
TYGAGGSTRSGTVKATEQIAADTTLTPVAHLTAVNHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVKHPQGVRYAAELVQLIKESGDFCVGVAAFPEMHPRSEDWDADTRHFVD
KCRAGADYAITQMFFKPEDYLRLRDRVEAAGCTTPIIPEIMPVTSVKQLERFAQLSNASF
PPELKERILTVKDDPAAVRSIGIEFATEFCAGLLSEGVPGLHFITLNNSTATLEIYEKLG
LHEQS
>A0A1U7GQT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetales bacterium 71-10|TrEMBL
MHILDIFDANPTTFSFEFFPPKTDKASADLFENMARLQELQPSFVSVTYGAGGSTRERTH
DLIVRIQQQTALTAVSHLTCVCHKEDELAGILDRYAASGIENILALRGDPPRNLEGYDRD
ADAFQYADQLVRFVRSRPSPDSRGFGVGVAGFPEGHPGTPNRREEMDNLKRKVDAGADYI
CTQLFFCNDDFYDFRERCDLAGVKVPILAGIMPITSRETMLRMYELALGARVPAKLLRAV
DRCTDNESVAKVGVHWATEQCRDLLDNQVRGLHFYTLNRSDATRRIYENLGVKDSLALAG
RRPA
>A0A842XH08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanophagales archaeon|TrEMBL
MEAYSNLMQEILNGKFVFTGELEPEKTTDLNELVEGAKPLVGYAVACNVTDNPQSMAYMS
SLVASYLVQRDAGMETIYQLRCSDRNRLALTADVLGAAALGLKNILALTGDHVSLGDNPG
AKAVYDLDAVLLTYMIRKMVDEGVDLAGKPIHEPPKLHVGVAVNPNADPLEAEIIKLKRK
EVAGAEFVQTQVVYEMEKVDSLFEIYNQYGIKVPVLIGIFPMKNYGVADYFDKNIPGVSV
PKELLEILKMASEITDKKERKEKYLEINLEYFENFVRDIMKSEAKGVHVMAVGYEQMVRE
LIARVRGEG
>A0A7W0PDK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MLSDDPRSRLRRRFAEQIVVCDGAMGTMLHSTGVPLDRSLCELNVTQPGLVRDLHAAYVS
AGADIIQTNTFDANRLRLSRVGLEDSVVELNIAGARLAREAVKDSDRTVLVAGSVGPANS
ATALSRIPSGMRAEVLREQIAGLVDWVDLLILETFGDLDSLVQAVEVALEETDLPIIAQL
TFGDDGRTLRGEDPAAVVAVLDRMDLAAIGANCTVGPAALQDVIAELAAASCSPVTVQPN
AGTPYRLGRQVRYVHNTAYFAGAAAEFVANGASIVGGCCGTTPAHTRAIAKAVSGLVPTG
RVQPLTPAYPQPAAARSTVAGTAPDRPTWPQDRGFVIIAGLGAPQGPDVGGFVEQARELK
AAGATVLAITEPAPPATRVGPVAAAVVLHERVDAEVLLPAETADRTLPALQADLLGAHAL
GLRMVVCRTGSPRVAGDYPDAALPWDVDSVRLIAALRGLNEGEDWRGVATRERTQFVIGA
SISTAAADLNREVERAEAKAQAGAHFLITDAIYDADEAIMLLAALPARGIDIPVIASIAP
FASFRTLERLRNEVPQMSVPPASIRGPGRPGDARSDVVEASIALIEKLRGLVCGVLVHVP
RASQQPAVELLSRLCEFRVRG
>A0A7Y2TR53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MTSFREALQSDRFTISAELTVRRDSNADDIRRQADRLAGLCDGIQVSDNPHAWVQMSALS
AAGILIEHGADPVPVLTCRDRNRLALHSDLLGFHALGVSSLLLMRGHRVPVGHSVPASTV
FDLTGRELIALAKSISPAGSAGESPFFIGTGARVFRPNRGWQADSLT
>A0A1T5INW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maledivibacter halophilus|TrEMBL
MLIKDKFKNKKPLISFEIFPPKKDYPVDTIYSTIDALKDLRPDFISVTYGAGGSTKDTTV
EIASHIRNKHRLSSLAHLTCLTSTKDEIQNTLNSLKKKGVRNILALRGDYPQEEGWDYKG
PNHYKYARDLISQIKKNGDFSIGAACYPEKHLECQSLEKDLLNLKEKVDAGTDFLITQLF
FDNEIFYDFKEKTAKLGIDIPILAGILPVLSKKQIEKITSLTGCSLPKKFLRILDRYEYE
PQALKEAGIAYAIEQIIDLLSWGVDGVHIYTMNRPKTTRRILDNIKTIRGVLTDEEAS
>A0A7W0NED1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MARAATPYPQYMSGTVRDQLAAGVPSFSFEFFPPKDDAAEAVLWRTLRELERLRPSFVSV
TYGAGGTTREGTVRVTERIATQTTMLPMAHLTAVNHSVAELRHVIGRFAAVGVRNILAIR
GDPPGDPSAEWIKHQEGIEYADELVSLVRRSGDFCVGVAAFPYKHPRSADIESDARYFVK
KVQAGADFAITQMFFDAEDYLRLRERVSTLGCDIPIIPGIMPVTSMNTIELAPKLSGAPF
PTALAATFEPIAQDKDAVRAQGIDQASQLCQRLLDEGAPGIHFITLNRSTATREIWANLR
ETSPVA
>A0A2N7PJ28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldimicrobium thiodismutans|TrEMBL
MEIKSHLEELLSSGKFVVTAEIGPPRNADPEVIKKKAKILKGYVDAVNITDCQTAVVRVS
SMASAVLVMSEGLEPVMQMTCRDRNRIGIQADLLGASALGIKNLLCLTGDHPKFGNHPQA
KPVFDLDSIQLIKLVRGLKEGRFENGEEIKGRRPYFFIGAAENPFAEPFDFRPLRLAKKV
KAGARFIQTQIIYNVEKFRKFMERCRELGLLDKVYILAGITPPKSLGMAKYMKYNVPGLE
VPDEIIKRLEDAKDKKEEGIQIAVDIIQQVKEIPGVCGVHIMAIEWEEAVPEIVKRAGLY
PREEAPSFMPPFVVEKVVEKVVEKPVEVIVEKIIEKPVEVIVEKVIEKEVPLEGEMAEEK
IFTLIEILSDLKASLKSLKAGMESLEEGIARLEEEFLKKKEARPIRKEVIKRPEERPVER
ETFIEEKPKIEEKVEEVVVKPEAKEVKPEVKPEVKPEIKPEVKPEVKPEVKKEEAPEEIK
PREEEKIEVKPVIEKPEAKEIVEEKTKVEVKPEVKLETKPEPEVKVEAIKIGGLKGIYRP
LSERAKNLPQDLYMEKATGEIKEVVIGKGDRAIKVGGVSTLNFHFFEGEMKNGVKFAFEI
LDIKPEDWPESLSKYYRDVFHDPALWAKKCVEEYGAEAICLYLVGTDPNFLNLPPQHAKK
VAEAVVKAVDVPIIVWGSGNAEKDVEVLREVADIVGERGAVIGPIVEANHRTLAAVAMGY
NTPVIASSPIDVNLAKQLNILLENMGLPLDKILMDPSIGALGYGLEYTYSVMERIRLAAL
FAQDTKLQVPFICSIGREVWKTKEAGLPTDELMGKAESRGILMEALTGVTLALAGGDLLI
MRHPKSIELCKELFRGLSMS
>A0A2V9FT48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRPHEHRRQPHGTKALSAAASWSRQDNGTVKIYDFNERLKDAILIADGAMGSMLHEAVGF
ERCFDELNSTEPEAVFRIHQAYIEAGAQIIETNTFGANRFKLAPLGLAEEVQRFNSRGVK
IAREAREAAAREVLIAGSIGPLGLGVQSRHPSPEEIQEIFHEQALALEERGVDFYILETF
SYIEELLLAIDAIRSFSGLPIVAQLTYAEEGTTYGDVRPADAAAQLKNKNVQVIGANCTL
GPQALLPILEELAAVDGLRVSGMPNAGFPKREGDRIVYPRSSPEYFALFAREAAALGVRI
LGGCCGTTPAHVRAMAEAVKLLRPSKTHPVVRSVETVLRPAPVAHREPESRFWKQLQKKE
FSVCLEIDPPKGLSLERIFEQVDKVMASKKVDAIDINSGAMARVGMDALIVAGALEARGI
ETVPHLTTRDQNIIGLQAALLGAWTVGGVRNVLTITGDPPSVGDYPETSGVYEVDSVGLV
KVLNRLNQGTDWAGKTLGGRTNFTIGVAVNPVADDLDNEIERFHAKVEAGAHFAMTQPLF
DPEHWNAFLKKLGGKPVIPVLIGIWPLTSYKQALRLSNEVPGIVIPEPLLKSMEAAGSAA
RDRGFEVARHMLAWARTELAGAYLIPPFKRYEEILEIL
>A0A0N1IKP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptomonas seymouri|TrEMBL
MADFISTILAEEDPNKWYTSFEFYPPRSDKAEDELMNVHLPAFAKQSPVFLDLTWGAGGR
TSDTTMRLSKEMQETYPNIPVNMHLTCTNMPAGLIKEALIFAKQSGIRNILALRGDAPPG
EEFRVNQNGFACAKDLVEYIRRDFCDDFCVTVAGYPEGHPSKIADDGTIAEEDYQDELDY
LKAKVDAGANVIITQLFYDASIYVHFVNRCREIGINVPILAGLLPITNYASFQRIVKLCK
THVPVDVKQRVEELKDDHEGLKNYGVEQCLSMIQYIRDAGIPFNHLHFYTLNSTSQAFKI
MQSLGIHVE
>F2UUF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces viscosus C505|TrEMBL
MHDNEPTGPTAAAGSRGEALSSAETGTARRLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPAGGVTGGGRQGSAHEPEAGRCKTAPRVRAVQEQTNPSECVLAH
VLDSSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRAEDVAGELRH
ADDLVRVIREVEADFFGDGRRHVTIAVAAYPATNDHIEAIEVLAAKQAAGADMAITQVFY
DAADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSSLGSASGAT
LVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDA
VDRGYLQATPGRGPSFLRRGSARATVSSHHPVQPLTTITKENA
>A0A2V8P230|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPARNPLREALEAGRFCYVVELVASRISREARLLEIATQLAQIPGVVAGSVTSYAGGSPG
HDPIRVGTAARARGLTPNIHVTCVSRDRHELGSLLKDLNALGLENVFALTGDYPKGSTPV
FDLDSVELVTLINQYREAGMPFWISVAVSPFKYTEPDCVYQYIKLEKKFAAGADYAITQL
GFDVRKFRELRRYLHERGIQKPVLGNVYVLNKRAAEKMAKGEPPGCWVAPELVEKVRTES
QAKDGGEAARLERAARMVAVIRGLGYSGVYLGGTQKAEHIRWIIERSESLAPQWEQLAEE
FTYAPKNAFYLYETPRQPAKPLGLWPRTLNFLGRTFPVRQETWLRKALVSIFRWIDRHPT
LARQLERAEFAFKSPVFGCQACGNCVLGDMEYVCPQTCPKQLRNGPCGGTNNGQCEVIPE
QACIWVRVYERAKTAKELELLKIYIPPPDRSLKGTSSYINYFLGRDSRPGRDRSNQSPPS
APSRTSEKDESKVALGQKI
>A0A2W4TWT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MQRFLDALDERVLVCDGATGTELYVRGVFLNRSFDELNLTQPDLVGDVHRAYVRAGADVI
ETNTFGANRMKLTTFGLADQVAAINREGARLARRVARDRAWVAGSIGPLGVRIEPWGRTS
VAEAEAAFREQAEALAEGGVDLFILETFGSLAEILAAVRGVRAAADLPIVAQMTATEPTA
VADGTPIERVTAELAAAGADVIGLNCSVGPAAMLETIEHMTRVFPGRLAAQPNAGRPRDV
DGRNLYLSSPEYMASYARRFVAAGVRLVGGCCGTTPEHTRQMAQAVRESAPAVRVSVSTA
DRPTRPEPQPVIDRRETSDLGRALANGAFAVVAEIPTPRGIDLEATVAQARRFCDLGAVA
VNVPDYPRTGARATALALAAMLERHDIETLLHFTCRDRTLAAMQSELVSAHVMGVRNLLA
TTGSPARTGNYPASTSTFEVDAIGLLNMASRLNQGLDVAGEPLGGATQFHLAATFNAFAA
DADAEWRRLDRKMAAGAEFIVTPPVLDPEAFEPALTRLRGLGLPILAGVAALESARHAEL
LSSEVVGVRASAAILDRLRRADDQAAAAADVTSEIVSWLRGRVDGLVITWLYGSAATAER
WVAEAGTPQRHSALHGAIQ
>A0A7W1LJ67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MSGTVRDRLAAGVPTFSFEFFPPKDAASEAVLWRTLRDLERLRPSFVSVTYGAGGTTREG
TVRVTERIATETTMLPMAHLTAVNHTLAELRNVIGRFAAAGVRNILAIRGDPPGDPTAEW
IKHPEGIQYAEELVSMVRRSGEFCVGVAAFPYKHPRSADVDGDARYFVQKVRAGADFAIT
QMFFDAEDYLRLRDRVSALGCDVPIIPGIMPVTSMGTIERAPKLSGAPFPPGLAATFETI
ADDKDAVRAQGIAQASELCQRLLDEGAPGIHFITLNRSTATREIWASLRETSSVG
>A0A2V9AZF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIFDFNERLKDSILIADGAMGSMLHEAVGAQRCFDELNSTEPEAVFRVHQAYIEAGAQI
IETNTFGANRFKLAPLGLGEEVQRLNSRGVKIAREAREAAAREVLIGGSIGPLGLGVQAR
HPEPEEIVSFFLEQAQALEERGVDLFILETFTYIEEILHAIDAIRSFSGLPIIAQLTYAE
EGTAYGDLHPSEAAAQLKNKNVQVIGANCTLGPQSLLPIIRELTSVDALRVSAMPNAGFP
KREGDRIVYPKSSPEYFALFAREAAAAGVRVLGGCCGTTPAHIRAMAEAVKSLRPSKVHA
SSIAVEAVAKPAPLLERAPESKLWKNIQAGQFQVSVEIDPPKGIALDRVYEQVEKIMSCG
KVDAIDINSGAMARVGMDALIVAGALEARGVETIPHLTTRDQNIIGLQAAGDPPSVGDYP
ETSGVYEVDSVGLVKVLHRLNQGTDWSGKTLGGATNFTIGVAVNPVADNLDEEIARFVSK
IEAGAHFAMTQPIFDPEHWYTFLKKLGGKSPIPVLIGIWPLNSYKQALRLNNEVPGIVIP
ESLLKSLESAGTAARERGFEVAREMLAWSRTELAGAYLIPPFKRYEEILEIL
>A0A2V8E8T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRPRAPAARRRIHEAVRDGGRDAARAPGGHALTNPLADAVAARRFCYVVELVASALKREA
QVLEIAAKLAVMPEIVAGSVTSYAGGRFGQDPVRVATAIRARGLPPNVHLTCVYDDRAKI
VNTLRALTALELFNVFALTGDYPAEGQAKAVFDLDSVQLVALVAKMRAGGRAPFHIAVAV
SPFKYARTDCLYQYLKLEKKVAAGANLAITQVGWDARKFAELKRYLDERAIDVPLLGNVY
VLGRRASERMAKGLPPGCWASPSLVDTISRESGAPDGGLEARLERAARTVAVLKGLGYAG
AYIGGTHDPDHVAQIIGRARELEPEWETCAADLQFGQPGGFYLYSSPAPARRRLPMVTRA
LDGAGRLMPVTRDTWLRRRLQRLSAWVDRRPPLRKLTERIEYAIKRPLFGCEACGNCVLG
HMEYVCPQTCPKQMRNGPCGGTFLTRCEVVDRECIWVSVHERAEAAGRVDQLKTYIPAPD
RTLQGTSSWINYFLGCDSRPGHDTSLPDRGGYRQ
>A0A2V9URT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPSDLLTRIKQSAVLCDGAMGTLLYSKGIFINRSYDELNLSQPELIRGLHHDYLQAGAEI
VETNTFGANSFRLARHSLADKVRDINLSGARLAREAAKSFDVWVGGSVGPLGTRIEPLGK
TSFDEARDSFRQQIQALVEGGVDLLILETFGYLEEIHQAMLAARDVGSKLPLVAQVTIDE
DGNCLDGSDPETFAPKLAEWGADVIGCNCSVGPVAMLDAIERVRAASSLPLSAQPNAGIP
RSVEGRNIYLCSPEYMASYARKFVTAGVRIVGGCCGTTPEHIRVMKAALRVGEARGKVAS
AHVAASQSAPRAVPAVPLENRSVLGAKLARGEFATMVEIVPPKGTDIRKEVEGAGFLKSV
GVDAVNVPDSPRASARMSNQALSLLIQREVGIDAVLHYTCRDRNVLCIQSDLLGAAAVGI
RNLICITGDPPKMGNYPDATAVFDVDAIGLVNIVHNLNLGLDIGGNPIGAGTGFVIGVGA
NPGLTDLDEEIRRFEYKVEAGAEYAVTQPVFDIRLLENFLRRIEHCRIPVVAGIWPLVSV
RNAEFMKNELRVSVPDSILERMARAPSPEAARAEGVAIAREMLIAVRQTVQGAQISAPQG
RYSSAVDVLEALGTSPAASV
>A0A7V3C5N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKTDALKELLKSSILVCDGAMGSQLYELAGPTRCFEELNLLQPEVVLRVHLNYIEAGARL
IETNTFGANRLKLAPHGLADRVGEINQRAVKLAREAREVSGVSVLIAGSIGPLGVGWRAR
VGREAEPETTEHARQVFAEQAAALEERGVDLYILETFPDLQELTWAVEAVRGQSSLPIIA
QLAYNEEGRTLGGDEASTATKKLKELGVAVVGANCSVGPQAMLDVLRAMAQVDGVSLSVQ
PNVGFPQRVGDRVVYPRATPAYFASFAREAVTAGASIIGGCCGTTPEHIRAIAQTVRDLA
PRREVRPSTAVVLEAPAPPTPKTEPVSGLYRKLQAGQFVVSVELDPPKGVHLDRILEAIE
QFQRSGGVDIVDINSGTLARVGMDALLLASAIERAGMETIPHLTTRDANIIGLQAQLLGA
WAVGGLRNILAITGDPPVLGDHPEVAGVYEVDAIGLVRIIRRLNEGADWAGRALGGATNF
TIGVAVNPVADDLDEEMRRFEQKVEAGAHFAMTQPIFDPEVWYKFLQRLRGKPPIPVLIG
IWPLTSHKLALRLNNEVPGISIPEHVVQELEQAGTGARDRGFELARTLYGWARGEAAGVY
LIPPFKKFEEALLVISD
>A0A6H9IIX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AY1-10|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6N2S3Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Blautia sp|TrEMBL
MKLAEAMKEKMLLSFELFPPKTDKGMENLPGTIEHLCKYKPEYISCTYGAGGTNVGKNMD
VCKMIKDAGTIPVTHFTCIGNTAEGIKDQLQNYLDNGVDHMLALRGDLPFGWTGTGGDFA
YATDLVAYVRKEFGDKIEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGITMPVDVGIMPILDQAATINMALSRNACVMPRELCEIISRNWIFPN
PFDKEPFDADVEGKKARFKEEGIEYTIRQIDEYRALGVNGIHLYALNKWKDVSEIIDRSG
MRTLV
>A0A839K1X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variimorphobacter saccharofermentans|TrEMBL
MKQYLKEHRLIPDGSMGTYYSLIKNQDRIISEYANITEPEVIKQIHKEYIKSGARLIRTN
TFAANRTVLQRNKEEQRELVIAACQIAKKAVEESSTELMISERIWILGDIGPIPENADSN
EKDILEEYRLLCDIFLEQGMDGIHFETFSSTNYIEKLAPYIKEKRQDMFLLTSFSVNKNG
YSAAGISATRLMDKIAQIDEIDACGFNCGIGSGHMHQILQKVTFPEGKNSYAAPNAGYPE
QMQNRMVFMDNARYFADNMKRIAELGIDIIGGCCGTTPEYIADINDMLRSNAYTPLVKQP
RSRREMAAPAVKENTFYRLFDSKDKVIAVELDPPYDANIDQVMECAHKLKHSGADIITFA
DSPMGRSRVDSVLMSIKIAGETQLPVMPHICCRDRNMISMRSTLLGAYIHGIRNMLVVTG
DPVPGESRVSTTGVFDYNSVQLMDYIREMNEEHFSDEPIFYGGALNYRRGTVDKVVDRMR
RKMEAGAKYFLTQPIYSEEDVMRIRSIKERVDTKILCGIMPLVSYRNALFIKNEISGIHV
PDHILNRYNPNMSREEAENVGASIAREIMDMLETVADGYYFMLPFNRVSLMDKIMRKEDM
Q
>A5EXW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dichelobacter nodosus (strain VCS1703A)|TrEMBL
MSDAAFKNLLAGYSLEVTPKFAESIANFTAYFAKETAAYVTFLPNSDFLSTIRATVLLQQ
NGLRTVPHIAARSLHSEAELEQGLAQLYDAGVRDLLLIAGSIDQPRGPWASTLALLASGI
IQNYQWHSIGFAAHPEGHPRIGADELLYTLQQKQAFADSISAQCYLLTQFCFTAKPIVHW
HRMLQTQGIRLPIHLGVPGVTTIGNLFRYAQLCGIGNSVRFLRYSQHGLHQFLELSTPEL
LLSNIVRARAQGELSLLKCLHFYPLGGFEATVRWIHQFQQSDDAEKTP
>A0A2V9MMY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTTGPMKAGSRLERVLRSGRFAVTAELNPPDSADPHAVYERALVLASVCDAINATDASGA
HVHMSSVGVCALLTRAGYEPVLQVSCRDRNRIAIQGDLLGAAAMGVQNVLCLTGDGVQAG
DQPEAKPVFDLDSITLLKTARILRDKGQFLSGRKLESSPQLFLGAAENPFVPPFDFRPWR
LAKKVEAGADFIQTQFCFDVPRLRQFMARVRDLGLHERVFILVGVGPLRSAKAAEWMRSK
VPGVVIPDEVIARLKGVSEGRQREEGRRVCLEVIREIRETQGVSGIHVMAYRQEELVAEI
VEEAGLLPRRAQPQQAGLE
>A0A354Z2W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MTPVSFEFFPPKTDEQRQQLDRTVARLAAWRPSFASVTFGAGGSTLSYTPETVSRLRANG
LDAIPHVSCMGGSREEIRSLLLLYRALGCRRLVALRGDLPSGMVRAGDFRYAAELVEFIR
AEHGDGFRIEVACYPEVHPQASDALADLHHFRTKVEAGADSAITQYFFNADAYFRFVEAA
RSIGVDTPIVPGIMPIANFSQLRRFSEQCGAEIPRWLLKRMQAYGDDADSIRELAADFVA
DLCRRLVAGGAPELHFYTLNLARPTHQVLARLAGEIVAEPIASERSAD
>A0A369LX99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonibacter sp. 28C|TrEMBL
MRSVSYIYETAKAAGRQPVSFEIFPPKGDLTLEAAHEVAAELADLLPDFVSVTYSAGGSG
NKQATAEVAAMIHDDFDIPTVAHLTCLGATEESISHAIDDLKRKGIASVLALRGDRVPGA
APSEGEPFRFAKDLVMRLADEGFCVGAAAYPEGHIECTDFKASVAHLRQKQDAGACFFVT
QLFFDNAYYYRFRDAADAAGIDAPIACGVMPFLGKAQIQRMVFMCGASLPSPIIKLLAKY
EDDPASLRAAGIEYACSQLVDLQESGADGLHVYTMNQPDIARACTSALRASWRQPSSGGP
GRAARGEAGAEASGGRA
>A0A5P8E6H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoprevotella muciniphila|TrEMBL
MRIIELIAQEERTAFSFEVLPPMKGTGLDRLRTVVDKLREFDPKYINITTHSAEYVYEER
ADGLMQRHAVRRRPGTVAVAAALQYEYGIPVVPHVLCQGFTREETEYVLLDLQFLGMTNI
LAMRGDKPKMPNLSKPLQEGEVNEHATDLIEQINDFNNGRFIDGTAMKEQGVPFSYGVAC
YPERHEEAPNMESDMHWFKRKVELGADYGVTQLFYNNAAYFDFVGQVRAMGVDVPIIPGI
KPFSKLSQLTSIPKTFRVEMPEALTKEAYKCKTDEDAYHLGVEWGIAQCKELIAHGVPSI
HFYSMGAAESIREIARAVY
>A0A3D4FUC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTSTTSTRLDRLPATAGAAAPPVRLIRDIYAEQRMLGQPVLSIELFPPKTPKGNALLFEH
ALPALRDLEPDFYSVTYGAGGSTRDRTIAIVDRIQREHQTTTMAHLTCISTSRADIEHFL
LDARKRGIRNILALRGDPPLDNGGPVERGFEYSYQLVEFIKAIGGFSIGTAGFPESHIAC
TEGKHVDWQRLKAKIDRGADFVLTQLFFDNDDYFAFRDYLTETLGVSVPITPGILPILST
DQIRRFTSLCGATLPAAVSAKLDAYGNDAAAVGEFGVEFATRQCEALLAGGAPGLHFYSL
NKPHAPTRIIGNLGLRG
>H0JWY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus pyridinivorans AK37|TrEMBL
MGDGTSEAGEPEVPRPAYPHSRVVAGSDRPEGATYAGPVTSDFVRATEDGGISRTPSIVD
RLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERLGPAFVSMTYGAGGSTRDRTVRV
TGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWEKHP
EGLEYADELVRLVRELGDFHVGVASFPEGHHRSPDLDHDTRYLVQKLRAGAEYSITQMFF
DVEHYLRLRDRVVACDAEQGLKPIIPEIMPITSLRSARRSLELSGSHLPPVLEERLRRAA
GDGPEENRAAVREVGIEVATEMCERLISEGAPCLHFITLNFARATGEVLDRLGYELEAPA
AVQPA
>A0A1C4YDE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora echinospora|TrEMBL
MALGLPSVLPNSQPSIGELIRDGQPTFSFEFFPPKTAAGETLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGDPTGEWIPHPEGVHYAEDLVRLVRDSGDFSVGVAAFPYRHPRSPDVVSDTEHFVR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILPGVMPVTQLATIARSEQLSGAPF
PSALAERFERVGDDPEAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWRNLQ
VGARV
>A0A2N2S399|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-21|TrEMBL
AEAGIKRIVALRGDLPSGVGDAGEFRYANELVAFIRAETGQRFRIEIAAYPEWHPQARSP
KDDLLAFKRKAEAGADSAITQYFYNIDAYLHFVDAVRGMGVDIPIIPGIMPIASFSKLAR
FSDACGTEIPRWMRKKFEAFGDDSESIRAFGLDVVTAMCEKLIASGAPGLHFYSMNQSAL
TTEICQRLKLA
>A0A0R2X998|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium BACL2 MAG-120507-bin38|TrEMBL
MNSAPTFSVEFFPPKDQAGEERLWSALKALEVYKPDFVSVTYGAGGSTRDRTIRITSEIT
ARSGLSTIAHLTCVGSSRDELIEILSQYKVSGIKSILALRGDPKGGPGVKWESTAGGFDY
ADQLVLLASSMGFEVGVAAFPDGHPASKGNFEQDIKVLLEKERCGASFATTQFFFDVKGY
INLVNQIRAKGSKLDIYPGILPITNFAQLKKMSELAGSAIPIEIQRRVEAAGDSPEEVVK
VGIDIASELSKDLLDYGVPGLHFYTMNSAAPTIEIIRRIGLR
>A0A401N7Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus erythropolis|TrEMBL
MTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSTEELRAMVGAYADRGISNILVL
RGDPPGDPLGEWKKHPEGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLAYDTKYLV
SKLRAGAEYSITQMFFDVEDYLRLRDRVSAYDAEQGAKPIIPEIMPVTSLRSVRRMLELS
GSSLPPALERRFDAAAGSGPEENRAAVRELGIDLATEMGERLIAEGAPCLHFITLNFARA
TSEVLERLGLTPDTSVGTAQAV
>A0A1F2QGZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium RBG_13_68_16|TrEMBL
MAHRRVLDRFADHIVVADGAMGSELLARVPGGAHLDLAPLERPNEVLAIHLAYLQAGAEL
IETATFAASRPKLDRLFASEVVEAVNSAGVKLAREARDISGVDCLVAGSIGPLAGVIDID
EPDGPGLIAVAHAEQAAILAGRGADLLILETFFRLDELRLAIEAVRDVTDLPLVACLSFP
FEKLPESHPEFAEQLRELFASEVLAAGINCAPGPQVTLDILEYLGGPPGAIAVMPNAGSL
VRRDGRILLPPATPSYLAQFARRAAELGAGLIGGCCGTGPDHIRAMAEAVRGLRPVHPRG
ARIAVEHPPTPMPSPQPRLQSTLAAKLASGEFVHVVQLDPPKGTNPDRIVEATRAMADAG
RVDAVDINSNPLARLRMDSLWLAAEVQRETGLETIPHITPRDASLMGLQAQLLGAWHAGL
RNLLAISGDPSQLGDYPGAHDVYHVDIFELVRSVSRLAEGFDCAGNPIGEPPGFHLGVAV
NPAADDLAHEVERLRRKADAGAHFVMSQVFFNWEPWERLLDRFAGRLPLPALVAIWPLPS
LKLALRLHNEVPGIFVPDELLKKLEASGSEASKVGIERARELLWAAPRYAAGVYLIAPFR
NPTEILHLLDDA
>A0A0F8UJG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp. 1.H.T.1A.1|TrEMBL
MLFNFREKLNSRKFLVTVEVSPPKGTRFSAPLEDACQLKGVADALNVTDNQCSIMHMSSL
AFSKLLLDQGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDHPTCGDHPGSKP
VYDLDSVQLIELVRKLDSGIDFAGKSLDGGTSFCAGAVSGIDPKNTLQLIKLEKKVKCGA
DFIQTQAVYDVGMFEEFIEAVNHLEVPVIAGLIPLKSLSMAEYMNKNISGIHVPEEIMLR
MKDASSPIEEGLSIASDTIKELTTLSRGVHIMPIGSHKNTPRLLSMAGISGK
>A0A5E9IQ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis F14-1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKARVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A5B8N8P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noviherbaspirillum sp. UKPF54|TrEMBL
MTQQNFSIEFFPPKTPEGVEKLRAARARLAELKPKYFSVTFGAGGSTQKGTLETVLEIKR
EGHEAAPHLSCIGSSRDSLRAVLNEYKANGIRRLVALRGDLPSGYGASGELRYANELVEF
IRAETGDWFHIEVAAYPEMHPQARSPQDDVQSFARKVQAGANAAITQYFYNADAYFRFVE
EARKAGVTVPIVAGIMPITNYSQLMRFSDMCGAEIPRWIRLKLASFGDDTASIKAFGLDV
VTALCERLLAGGTPGLHFYTLNQAAATTEICRRLNGSSR
>A0A2J6XWJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyoglomus sp. NZ13-RE01|TrEMBL
MNFRDKVLSNKFVITAEVTPPRGVNVDSYIKRSLLLKGKVDALNVTDFQNVGVRLTSLVG
SYLLLKEGIEPIFQITSRDRNRLAIQGEVLSAYVLGIRNILVLTGDYPTTGIMKDAKPVF
DVDATNILNIIKNLSNGEDSSGKKLDGIPQFFLGAVFNPNLTPLELEVLKMRKKHEAGAE
FFQTQLFFDLSLIERTRSLIKDWEPKILAGVTIFKSREMLNYMISKVPGIKIPSDIVEML
ENSKDIRKRSIEFCAELCLKMKESGLVNGIHFLASRPSDILEVLELLGW
>A0A261GEU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hahella sp. CCB-MM4|TrEMBL
METQKQFKRRFSFEFFPPKSQEGMAKLQTVRDELADRNPDFFSVTYGAGGSTRERTIDTV
LTLHKQGISTAPHLSCVGATRESVAELLDLYKENGIQRIVALRGDLPSGMGTGGSAELRY
ANELVEFIREHTGEHFSIEVAAYPEFHPQARNAEDDLRNFQRKVEAGATSAITQYFYSPE
AYFYFVERCEKAGLNIPIVPGIMPITNYSKLARFSDMCGAEIPRWIRKQLEAYGDDMASI
VKFGEEVVTRLCEELLKAGAPGLHFYTLNQAAPSLAVWDNLGLGDKISF
>K0IX50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amphibacillus xylanus (strain ATCC 51415 / DSM 6626 / JCM 7361 / LMG 17667 / NBRC 15112 / Ep01)|TrEMBL
MKTLDLFDSKKVLSFEIFPPRQPGSVNMIYDTVEQLTELDPDFISVTFGAVGQGTRSKTV
EIASKIKNHYGIESVAHLPSINLSKTEALNLIREFEEQGIKNILALRGDINPNIAPKNEF
NYASDLVSFIKEHGDFNIIGACYPEGHIESDSIVKDILYLKRKVDAGTDHLITQLFFDND
YFYSFQEHAAIAGINVPIQAGIMPVVNKRQIERMVSLCGVKLPKKFLAMMQRYEDNPEAM
KEAGIAYAVDQIVDLITQGVDGIHLYTMNKPDIAHRIYHAINKLLVI
>A0A1V5SM82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium ADurb.Bin277|TrEMBL
MRISSFYKTGKPVISFEFFPPKTPEGERKLYESAAELKELRPAFVSVTYGAMGNTQANTL
RVVSEIRNRIGIETAAHLTCVAHSRGEISGILEKLAAARIKNIVALRGDPPQGETEFRPV
ADGFRYASELVRFIRSHSRFGETFDLIVAGYPEGHPECRDLRKDIEHLKLKVDAGANAVN
TQLFFENGFYFDFVERARKAGITVPIVPGIMPVTHGPQIEKFSKMCGTKIPGEIRRAIGQ
FGDDQDSITHFGIDYATRQCLELLKGGAPGLHFYTLNQSRATREIYANLGLSV
>A0A2R6WD43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marchantia polymorpha|TrEMBL
MKVIDKIKEGEANGRVVYSFEFFPPKTEEGVENLFERMDRMVAHNPSFCDITWGAGGSTS
ELTLDIANKMQNMICVDTMMHLTCTNMPVEKLNSALDTVKANGIQNILALRGDPPHGQDT
FVQVEGGFSCALDLVKHIKEKYGDYFGITVAGYPEAHPEVILEESGATEEAYRKDLEYLK
KKIDAGGELIVSQLFYDVDIFLKFLDDCRQIGISCPVVPGIMPIVSYNGFKRMTGFCKTK
IPAELTAALEPIKDNEEAVRAFGVHYATEMCKKILAHGVTALHMYTMNMETSALRILQNL
GLIDITRVNRSLPWRPPTNQKRNGEEVRPIFWANRPKSYITRTTEWNEYPQGRWGDSRSP
AYGTLNDYQFLRRRTRNKKLAKEWATPLTSVADVHEKFVKYCKGEINTIPWSEVDGLQPE
TKTINEDLVDVNNQGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYVEFFCSAEKLQ
ALVEGIKGTPLTFIAVNAKGETKSNIGPGDVNAVTWGVFPAKEVIQPTVVDPVSFMVWKD
EAFQAWTDEWASLYPENDSSRKILSEIASSYYLVSVVDNDYINSSLFKVLRA
>A0A1Q8GDW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. C18|TrEMBL
METQKQFKRRFSFEFFPPKTDKGWEKLQGVRNTLAEVDPDFFSVTFGAGGSTRDRTVQTV
LDLHKRGVSTAPHLSCVGATRDSIAELLDVYRDNGINRIVALRGDMPSGMGAAGELRYAN
ELVSFIREYSGDTFNIEVAAYPEFHPQARTAEDDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVITEMCAKLLAAGAPGLHFYTLNQAEPSLSIWKNLGIGEREKIAF
>A0A0H3AN77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A413UQT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM40-7AC|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLNTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAQMITSEFNTPSVAHLTCVGRSHADIAAKIDEYRSAGVENILALRGDLPAGAT
EDDKPASDYAYARELIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELANKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A3P7GMC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wuchereria bancrofti|TrEMBL
VFLSAVYFSVVIPQACSKKWGESRTDWVANGTYVPLRDRIKKRVAKGIPFFSLEFFPPKT
TNSVANFFARLDRFREGNPMFVDIAWHFGSDPGNISSETSSSSVAAGCLDYCGMDTMLHI
TCCPYTKEQSIRHLEQSKALGLKNILALRGDLPRQDENPVLYKYRALDLIRWIKEEYNDY
FTIACSGYPAGHPEAPSYRADLLYLKAKVDAGADFIISQIIFDGEVFQNFLRDCREIGIT
VPIIPGILPIQSYESIRRIAELSQLVIPDSILTSLEPIKNDDDAVRNFGIWHAVTLCRTL
FSNGSATSIHLFTLNREASSREILQQLGLWPRSPMRALPWRLFGENHPVRCKEDVRPIFW
SMRPKSYVFRTREWDEFPNGRWGNSSSPAFNDLKDYYLFYLKGQPTRDEQLRMYGERLET
LADIQKVFVNFITQNINENGVKVSQLPWNEQHDGIRAETSLIKDQLLWCNSNGFLTINSQ
PSINGAPSTDPFVGWGKPGGYCYQKAYLEFFTSQANAEVLWNLLPSYSRLNCHIVNHDAT
IDWTNTETTMPIAVTWGVFPGSEIAQPTVVDPLSFRVWKDEAFSAWLNWSSIYAEGTSSR
CLLEKIYNEYCLVTLVDNDYPKSTIIFDCLAQLVNR
>A0A0D8HED2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithrix ferrooxidans|TrEMBL
MKNLVRVDQLISSASRPLFSVELWPPRNVESERRLTQALLELSELSIDFVSITYGAGGST
RENTHDLVVKLDREYSLTAVAHLVTAAHSKVEIDSILSRYAKGGIVNLLALHGDPPLSGN
DQLLDGEFPHAIDLARYAIEKYDMCVGVAAHPQGHPSAFDRESDIRFLAEKLEVAHFGIT
QFFYDSNYYFDLLSRLDSIGIQKPIIPGIMAPTSLSTLIKMSELSGAEIPKVVLNRLNRY
QGDPQSLKKEGIEIAIELSQELLDGGVAGIHVFTMNQASTTKAIYSALFPGRSAASK
>A0A1S0V5J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylella fastidiosa 32|TrEMBL
MIPISFEFYPPKNDDQRAQLDRTANRLRAFTPEYVSCTFGAGGSTLSYTSETVRHLSQHH
GFDAAPHLSCVGGSRQEIRELLKLYRAIGCQRIVALRGDLPSGMGHPGDLRYAADLITFI
RAEHGDHFHLEIGAYPETHPQASNTLNDLHYFKAKADAGADAAITQYFYNPDAYFHFVDA
VQRLGVTIPIVAGVMPISNFDKLHHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVV
TALCERLIAGGAPGLHFYTLNLAKPSTQVLQRLGY
>A0A0R2Y1K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas libanensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKIPAAPHLSCVGDSKDDLRGLLTHYQQAGIQRIVALRGDLPSGMGMASGELRYANEL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQGFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2T4R042|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus simulans|TrEMBL
MSRFLQTLSKNVLVADGAIGTILYSEGIDTCPEAYNLTHPKKIEQIHRSYIEAGADVIQT
NTYGANFEKLQAFGLEHQVRDITRAGVRIAKQAANEDTFILGTVGGFKGVKQNDLSLSTI
LYHTDIQIETLIDEGVDALLFETYYDLNELLQVIRATKKKYNIPVIAQLTASSTNYLQDG
TEINEALKQVEAEGADVIGLNCHHGLHHMQQSFTHIEIPQHAILSCYPNASLLDFEDSTI
HYSDNASYFGKIAETLVKEGVHLIGGCCGTTPEHIRFIKQAVEGLKPTLEKKVIPIRRKS
NYPSIPVKKNNLTTKVKAGPTVIVELDTPKHLDTTKFFANVTKLDKAKVDAITLADNSLA
TVRVSNIAAASIIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKV
GHLPGATNVYDVNSRGLTELAVRFNQGLNIDGGALKTKTNFNIAGAFNPNVRKMEAAVKR
LDKKVDCGMSYFITQPVYTVERIQEIAEKTAHLDTPFFIGIMPITSFRNATFLHNEVPGI
SLPDEILDQFEAVKDDKQKTKELSLRICRNLIDEIIKHFNGLYIITPFEQVDFSLELTHY
FKKQTEKNQEAII
>A0A164SVX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis|TrEMBL
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTRAKEFIS
VHHERTEPGLDKIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPVYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMARAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>A0A1F9L6R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYD12_FULL_56_24|TrEMBL
MKSGSRLERILTSGVFAVTGELGPPKNGNAELVREKARLLKGSVDAVNITDCQTAIVRMS
SISAGLLTLAEGVEPVIQMTCRDRNRIGMQSDILGAAALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMVKSMRDEKIFQSGEVIKSHEPRLFLGAAANPFAGPSEQFRAARLAK
KVANGADFVQTQIIYNVERFARFMQAVRDLGLHKKVHILAGVTPPRSLGMARYMQSSVPG
MDVTDEVIKRMQGAKDKEDEGINICVDIIRQVREMEGVAGVHIMAIEWESAVPEIVSRAG
LASRPVFADEPFALVPSAVTPAAPIEVRTTVAGVEESDALLAAAKIEAEKIIAAARAEAA
QFRASAATGGSGAGAVAQAMIETDEAGEDAMNEKERQMALDSVRLGLDALKKAYGLSDDQ
FDALVKFAGAEAILKREPVLAAPASSAPTPVAPAPMAPAPVHDESVAKKAAEEKAAAEAK
KAEAAKKAAEEKAAAEAKQAEAAKKAAEAAAADEAKKAEAAKKAAEEKAEAEVKKAAAPA
PKKASPATAAVGAAELTLEKTVLRERAAKVPEASYKQAYTGAIRQTVLGDAASGIKVGGA
NTLSFHLFEGAMPNRPQIAFDVLDVKPDEWPDTLARHYQDVLDNPLAWAQKCVKEYGADA
ICLSMVSTDPNGLNRPAGEAAKAAAEVVKNIEVPVIVWGCGNGEKDTETLREITSLIGDK
KVCLAPLSDSNYRAIGATAMAFQYPMVAASPIDVNLAKQLNILLENLGVSLDSVLIDPSI
GALGYGIEYTYSVMERIRLAALTQKDEKLQVPFICNLGREVWKAKECRLPTDEMIGDQET
RGILMEAITASIMLMAGGELMIMRHPRAVALTKSLITGLMG
>A0A2E4QT12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hirschia sp|TrEMBL
MSDLNISFEFFPPKNDAMADRLWDSVQRLSPLDPSFVSVTYGAGGSTRERTLDVVGRIAQ
ETPMVAAGHITCVAASKAEVDDVLRGYWNSGVKRIVALRGDPVDGIGARYEPHPEGYAFA
SDLIEGARKIADFDISVGCYPENHPEARGLADEIDNLKRKLDAGADRAITQFFFEPATYL
RFRDAAADAGIDKPIVPGVMLQSNFKGLTRMAKMCGAYMPKKFVDLYDGLEDDAETRDLV
TAHLVADMCNKLMEDGVKDFHFYTMNRAGLSLSTCRLLGVKPKLQETA
>A0A853DQM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia naganoensis|TrEMBL
MSCTTARYSFELYPPRNERAAAALPATIDRLAAARPDFISVTYGANGSSRTSSLDVLRHI
LERTDVSPMAHLTCVGSSHEEANRLIREFLDAGVRRFLAVRGDPPEGAAPGEDGIGDIRS
SAELVQLIHRVQAERVPYGELTVPGLPAQAVLTRREHVQIAVAAFPNGHPASHSISQDID
ALLAKQAAGANLGITQLFFHAEDYLSFAQKANDAGVAFPILPGIMPVTSPARLSRMLELS
GEDLPSDLAIQLEVEPTDEGRREIGIEWAAGLGRRLLDGGAPGLHLYTFNQSEAVLSVLD
RIGVLPAPDSISSATEREPA
>A0A1C0SY92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. LC54|TrEMBL
MTASTRHDVETALFRNYSLEITGKDIGQIEAARSEIPVGAPINIAFLGNETHAQRIEAAA
RIRKWGFEPVPIISSRRLRSVQDRDELLGGLISAARPTRFMLVGGDPSSPAGPYKDSLDL
IAGGIIADHDIVHVGIAGYPEGHPRIDRRRLWEALEQKVELLKTCGCTVEITTQFGFDAD
AVIDWIVEVRARGIDVPIRIGVPGPADVKRLLRFAAQFGVASSAAIVGKYGFSLANLVSK
VGPDRFMNRLQGGMTGRDLGAVLLHLYPFGGIAETVAWAARAAGRQITESEGGTLGRAPY
P
>A0A0Q8FGB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. Root655|TrEMBL
MTAPAPRRVIGPVARAGERTDRPRVSFEFFPPKTEQMEENLWAAINRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILEETSLKPAAHLTCVGASRAEVDEVIREYWETGVRHVVSLRGD
PPPGEGGIGGVYVPREDGYKNATELTSALTSIAPFNVLVGVYPEKHPESPSIAHDIEVLK
AKVDAGATLAISQFFFDTDAFLRFVDQVRKAGITIPIVPGVMPVTNFKGLVKMSKACGTA
VPGWLANLFDGLDEDADTRRLIACSVAAEMCAKLQEQGFSDFHFYTLNRADLVYAICRVL
GVRETAPASSEAAA
>U2AEC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 863 str. F0517|TrEMBL
MKVTEHIAKAKGETLFSFEIVPPKKGNNIEELYKNIEPLLEFKPPFIDVTTSREEYIYKE
HPNGLLEKKLIRMRPGTVGICSAIQHKYNVDTVPHVLCGGFTKEETEDLLVDCFYLGIDN
IMALRGDAMKEEKYFRPTKNGNIYALDLVKQVDNLRKGIFLHDTLETNVGMDFCIGVAGY
PEKHLEAPSKTFDLEKLKEKVDNGADYVVTQMFFDNQKYFDFVKKAREMGINVPIIPGIK
PISVKKHLNLLPQAFFLDFPEELVKEIEKCKNNEAVRKVGIEWAIAQSIELKKAGVPSLH
YYSMGKSENIIQIISQVF
>A0A3E1BIC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGNFEISVSAYPEKHPESRDRAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGINDFHLYTMNRAPLVSAVLDNLGFSRRPAKSAGAAA
>A0A1C0SYF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. LC54|TrEMBL
MSPDFNPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNVMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAKDQKKEGKQLCIDIINEVKEIEGISGVHV
MAYRQEEYVAEIVHESGVLKGRQPWKHETLPADALVAERLEHIREGKEENQQEMAEAAAH
HPH
>A0A2K5VEN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macaca fascicularis|TrEMBL
MDHRKARVLPAGHYCPSLGIWASKAGSVRFSVPPSISRNLAMVNEARGNDSLNPCLEGSA
SSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDALELLNRPTQNERETEAP
>A0A1W2EFP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa malonica|TrEMBL
MLINKLGKSFVYTTELGGINGIDIDESIAKVRDYDGLDAINIHDCPNARLRMNSVMAAAV
INRATGIETIPHYTCRDRSLLGTQADLLGAHALGIRYLLPTTGDGPQHGPYQSAAVYDYN
TAKLLELIKNFNQGKDANGEGFKGQTQFTAAATATPGAVNLDAEIAKMLRKINAGADFFQ
TQPVYDAGQALEFLEKARALGKPVLLGLMPLKSLKMAEFVNKNVAGVTVPPNILAEMEQG
KTGFEVACEFIRHVYRQVDGLHIFGMGDVAVTNKLIAFTRNLLK
>A0A562IP32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter roseus|TrEMBL
MTGTVRELLDQGRPTWSFEFFPPKDAAGETQLWTALRELERLQPSFVSVTYGAGGSTREG
TVAVAERIAAETTLLPLAHLTAVDHSIAELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WVAHPDGVRHAAELVALIKDAGDFCVGVAAFPELHPRSPDAETDTDMFVAKCRAGADYAI
TQMFFRVEDYLRLRDRVSARGCEVPVIAGVMPVTSVRQITRIVELSGQAFPAELADRFAA
LDGDTPEARRAVRELGVEVATDMCRRLLDEGVPGIHVITMNRSAAALELHAALAGAPAV
>A0A414NYB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mitsuokella multacida|TrEMBL
MKRISVELVPRDEDALRGELALLGKFKEQVDVINIPDLLRFPTRSWQGAAIAKEYFPESM
PHIRAMDIDLDKELAMKDYLREHDIREVLVIEGDPPQDMMHEVYPTNSVDVIWKFRKEMP
GVKVYAGIDQYRGSLSQELYRIKRKLQAGAAGFFTQPFFDMRFLSVYADMLQGLEVYWGV
SPVMSARSQSYWERKNHVVFPHAFEPTLDWSVAFAKEVMDFAEREGNNVYLMPIKTNLEA
YLEGVLA
>A0A1H7NHF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. DSM 11652|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLADFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFQIEVAAYPEMHPQADSFDLDIKRFCEKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A178DGL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenochaeta sp. DS3sAY3a|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRALVDDALEQAKVLGIRNILALRGDAPRSEE
YREEGQLPEQDSNTDFTWAVDLVRYIRKQYGDYFCIGVAAYPEGHSDESHPEHQDPLFDL
PYLVEKTKAGADFIMTQLFFDVEAYDKFEKTLREHESGVFKTIPIIPGLMPVQSYKILLR
TTKLSHAKLPADVLARLDAVKSDDELVKQVGVKILDEIVEHIKTRPDVGKRGFHFYTLNL
EKAVSHIVEDSHLIPQTTPEDDDEVIIDTTPAINLEPPNGALTRERRRLSSINSGPRNRV
IISHPSATKSSNHSFEAPESEAGIPRGPVNTRANTLAISEGEGSLGREATWDDFPNGRWG
DARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKDDVSKLFKRHIEGDLEAIPWSEQGLS
PETSTISAQLLALNAKGWWTVASQPAVNGVKSSDPIFGWGPKNGYVFQKPFVEFFIPSAQ
FATLKARLDAHDQITYFAGNAAGDFEASDEGSVNPVTWGTFAGKEIVTPTIIESVSFRSW
LEEAFSIWNEWQRLYPTKSASGKLLGGLKDDVWLINVIWGDFVEGDGLWEFLSA
>A0A1I0N9A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sp. YR573|TrEMBL
MYTKTTLRDKIIEAKTGLVFYSLTPPKINTEENKVLTIANNQIERLKYLDIDGLILYDIQ
DESLRTEKERTFSFIPTIAPEHYGKEFLSELNIPKIVYKSIANLTKTDFQNWLIRNENLE
YVVFVGASSHQQIEATNFSLFDAYNIKKEFANKLLLGGVTIPERHSKKGDEHIRLFNKMD
NGCNFFVSQCVYNLNDTKDLLSDYYYHSLETGNNVAPVIFTLAPCGSFKTLQFMEWLGIQ
VPKWLYNDLKHSKDILEASINTSTNIATEILNYANAKNIPVGFNIESISIKKEEIEAAQE
LLGNIMHLVKRN
>A0A4R3H8M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. BK020|TrEMBL
MTVPPLRRVLGPVARAGERTDRPRVSFEFFPPKTEQMEENLWAAIKRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRAEVDEVIREYWETGVRHVVSLRGD
PPPGEGGIGGVYVPREDGYRNATELTSALRAIAPFNVLVGVYPEKHPESPSIEHDIDVLK
AKVDAGATLAISQFFFDTDAFLRFVDKVRAAGITIPIVPGIMPVTNFKGLVKMSAACQTA
VPGWLANLFDGLDEDADTRRLIACSVASEMCAKLQEQGFSDFHFYTLNRADLVYAICRVL
GVRENAPTASEAAA
>A0A6P5JE73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phascolarctos cinereus|TrEMBL
MAELPYMSHPRSRVCRHGHCCWSLGKGSQETGSLCFSVPPSISCRNPAMVNEARGSSSSE
GSSSGSEGSKDSSRCPTPVLDAERHERLREKMHRRMDSGDRWFSLEFFPPRTAQGAVNLI
SRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVDYCGLETVLHMTCCHQTRDE
ITSNLHKAKRLGLKNIMALRGDPMGDEWEEEENGFCHAVDLVKHIRSEFGDYFDICVAVI
SPNSSPCLSGAESHLRRSERHAQQVKVMMGQASWRLNLVRNLRGHVVQPFLGTPLSSLPN
HFPPRLCWNVAINGYPKGHPEAASFEEDLQHLKEKVSAGADFIITQLFFQADTFLNFVKA
CTAMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELA
VAMCQELLASGLVPGLHFYTLNREVATVEVLKRLGIWNEDPRRPLPWAVSAHPKRRVEDV
RPIFWASRPKSYIYRTQAWDEFPNGRWGNSSSPAFGELKDYYLFCLKSKSPREELLKMWG
EELTSEESVFQVFTYYLSGEPNQSGHKVTCLPWNDEPLAAETSLMKEELQKVNQRGILTI
NSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSETVAALLQVLKKYELRVNYHIVN
VKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEE
SPSRMIIQYIHDNYHLVNLVDNEFPLDNCLWQVLEDTFELLSRPAPQ
>A0A100VN49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus amylolyticus|TrEMBL
MKADLRKAMQERVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFADLGARIIGGCCGTTPDHITAMKEALADYVPLPILEPDPSE
SKPRIVLHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQRAGFVIGAAFNP
NVKYLEKAVQRLEKKIASGADYIMTQPVYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A6P1C5F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium tropici|TrEMBL
MSHIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLTEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEIIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRSDALVAERLHQISEGREENQQAMAEIAA
HHTPPQTH
>A0A5M9WJV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus amylolyticus|TrEMBL
MKADLRTAMKQRVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTDI
FETNTYSANFDKLSKFGLESKVEDVNRAGVRIAKEVAGTENYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVAGRVGVPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFADLGARIIGGCCGTTPDHITAIKQALADYVPQPIAEPDPAE
ITSRIVLHENVDERAGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRALVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDPQLIVAMREATKHLDIPIFVGIMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVTIAKELLDVATEHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A0C4Y6I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus basilensis|TrEMBL
MQDRYFSFEFFPPKTAEGAEKLRNTRAQLAPLQPKFISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRDILKTYREGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLENFVRKVKAGADSAITQYFFNADAYFRFVE
DVRAMGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWVAKRLEGFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNTASATKAIWQRLKL
>A0A4S4FJS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naasia lichenicola|TrEMBL
MAKTAPAANPESAVLLESFSLEMTGKDVPGLEAARGAIPAGTKINVTFLGNEDLDMRVAA
SKAVKDFGFTPVPHISARRLASQEQLEEFLGRLQEVGATEHVFVVGGDPAEPLGPYPDAL
TVIRTGLLQKYGVREVSIAGYPEGHPDIPTDVLWSHLEDKASALKEQGLDGVILTQFSFD
TDPVIAWIDAVRARGIDHSIRIGTPGPAGIKRLISFAGRFGIGANALIVKKYGFSLTNLM
GTAGPDRFVTDLAALLATRENAGDVKLHFYTFGGLLSTAEWARDYLTGRH
>D6SXF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis AMD|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIAHTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQEAAGVFEHASDL
VYYIRSKRPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGVNVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNADCLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A077PML3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus bovienii str. kraussei Becker Underwood|TrEMBL
MSFFHANQREALNQNLAELKGQIRVSFEFFPPSTTTMEQTLWKSIERLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKDKTGLDAAPHLTCIDANREELRNIAHDYWESGIRHIVALRGD
LPDSSGKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKNAQSDLINLKRKIDAGADRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFAKMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A2M9LR34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02613|TrEMBL
MALGTASTRTDHARTVREMLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A1Z9TPX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium TMED261|TrEMBL
MGRLSEKFLSGSFVVTSELTPPKGTDVDALLEKADLLAAAVDAINVTDSHGSKMSLSPIA
AARLIADRGVEPILQMTTRDRNRIALQSDMLGAWVLGIENLICMGGDPPHLGDHPEAKPV
FDIPTEELIRAALSLNKGNDLMSNSLRGKTGFKVGAVVNPGADDLEIEIARLEKKVESGA
TYFQTQAVFDADSFSDFMERVSHLEVKILAGIMPIKSVKMAKYMNDNIPGISVPESLVSR
IDLADDLIEESLAISAEVIQGLKSCCAGVHIMAPGWEKNIPALVERCELVR
>A0A1Y5DRI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp. 41_12_T18|TrEMBL
MLAQKIKNRESGIVVYGITPPKKSSDEEKVKEIAARQVERLQGLDIDGLILYDIQDEKTR
TSEQRPFPFMETLDSLAYSRDYLSALDIPKIIYRSVGKYSKSELSQFIDELSQEDDLTVF
VGAASKAQSVSLSMSEAYQLKQQVNAALPLGGVTIPERHQVKGDEHLRVFNKIKQGCQFF
VSQGVYDVEASKNFLSDYYYYGREHNIPLVPILFTLTPCGSVKTLEFMKWLGISIPRWLE
NELVHTNDILQKSVDISEQNWRELKTFADERNIPIGCNIESVAIRKVEVEASIELLQRIQ
NSE
>A0A317WEL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus sclerotioniger CBS 115572|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLGKVDAALQAAYKAGCTNILALRGDPPREKEA
WEATDGGFRYAKDLVHYIRGKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGASF
VITQMFYDTDNFIEWVKKCRDRGINVPIIPGIMPIQTYAAFIRRSNWTKVRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
IQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSIRDLTHIFVSFLEGKLARLPWSDTPITTEANAIKESLVE
LNKKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLLDELIARIDKNG
DLTYHAISKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGEDWA
KCHEASSPSRKLIQGVMDSWYLVNIVNNDFHNTSNLFDLFKGLDVQDLDTEIPVENGEPK
THTNGAANGTTNGVTNGAAPDTAVKN
>A0A8B9E008|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anser cygnoid|TrEMBL
GRDLSCLIPTVLLVFPSSRELTMVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPV
LDAERHERLREKMRRRQDSGDRWFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWH
PAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMAL
RGDPAGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKE
KVLAGADFIITQLFFRSETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEV
PQEIKDVIEPIKDNDAAIRNYGIELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRL
GLWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPA
FGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWN
DDPLATETNLLKEQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFF
TSSEIVTALLKVLKKYESRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVD
PVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVV
DDTFELLNSPAQQ
>A0A656YPX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens ABAC62|TrEMBL
MSTDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGIASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A180GJV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia triticina (isolate 1-1 / race 1 (BBBD))|TrEMBL
MFYNVDIFVVWVTEIQTAGITVPVIPGLMPIQSWAQFKRVTNFINTVVPQYFSDKLEPIQ
SDDQAVREAGTKLVADTPEK
>A0A413M6V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIKAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNTIPKTFKIDLPQELASEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>J9J1L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxytricha trifallax|TrEMBL
MKIIDKINQVLEEDQSNKKTFYSFEYFPARTEQGIENLLDRIERMGSTNPLWVDVTWNAG
GSSSDQTLELCSHIQNFSGLDVLMHLTCTFMDREKIVSSLDRAKELGIKNLLALRGDPPR
GAKDWIPIENGFNYAVDLVKFIREQYGDYFCIGVAGYPEVHLSATSREDDIRYLKEKVDA
GADFIITQLFYDNNLFVEWVADCRRAGIECQIIPGILPILGYERFNKTIQFCKTIVPQKI
LDDLEPIKNDDEEVRKYGVKFGIEQCRELIDQGTRFLHFYTMNLETAVVNIIKGLGILDR
QKDLPFKKLSCRRTEEVRPIFWAIKPKSYISRTQEWDEFPNGRWGVSRSPAFGEPEMYGS
IAKKISFNFDEQRKIYGENVNSLQDISEIFIKYLKGDIKKYPFSEGSLQLETNVILETLV
KLNKNYIFTINSQPKVNGVSSNDPKFGWGPKNGYVYQKAYIEFFIPNQLIDKLVDYLNNF
EMLTYQAVNNSGCEIKNVQPNDVNAVTWGVFKAKEIIQPTVVDHKAFLIWKQEAFQSWLD
KWGIIYGLDSTQFKFLESCQNQFYLVNVVDNDYINGDLNKIFLDFIDQNEEIISTL
>A0A4P7UL42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio desulfuricans|TrEMBL
MHIGQMIRKLSAPFYSLEFFPPSDTAQLPDFYATVDRLRALDPLFASVTYGAGGTRQQNT
LAVTAELARRGITAMAHLTCVGADPQSISVFLGELRAAGVNNVLALRGDPPADRPWSWDS
AHFHHASDLVAFARQQQPGMGIGVAAYPAPHPESPTFADDRRHTADKLRTGADFALTQLF
FDAREYEDLVANLRGQGITTPVIPGILPIQGFGSLRRVLSLCGANIPGKLYLALEKAHND
GGAEAVRQVGLDYAVRQIRRLLDAGAPGIHLYTLNKADMCLRLAEAVGKL
>A0A7K6X4Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Promerops cafer|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6A0BL71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rutgersensis|TrEMBL
MALGTASTRTDHAPTVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSEDWDTDIRYFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LQDDKG
>A0A857DI05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter restrictus|TrEMBL
MFISELFQQKKVVSFEIFPPKLTPSIEVIYDTIDALAPLRPDFISVTYGAGGSTSKTTAE
IASIVENKYNINSLAHLTCITSSKEQIEGTLTQLADSNVSNILALRGDIPKGSEETGRAR
DFQYASDLVAYIQDKHSFCLGGACYPEGHPECPNKDQDIENLRRKVDAGVGFLVTQLFYD
NDAFFRFQEKVANLNINVPILAGIMPITNRGQIERILSLSNARMPQKLIKILDKFEHNLE
ALKDAGIAYATKQIVELLANDIDGVHIYTMNKPQIAKDLVRNLDSLFYAVNSQETRKEGN
LA
>A0A2S5NRZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp|TrEMBL
MKQNLPLSFEFFPPKTADGISNLRETRAQLAQYNPEFFSVTFGAGGSTTDRTKETVFEIQ
AEGYQAAPHISCISSSKEEIRELLSAYKAKGIKRLVTLRGDVPSGEVSVGDFKYANELVS
FIRQETGDWFHLEVAAYPEFHPEALSAAKDMANFKRKVESGADSAITQYFYNADAYFRFV
DSCEADGITIPIVPGIMPIYNFTQLARFSGVCGAEIPRWLRLRLEAYADDLPSLRALGVD
VVSELCETLLAWGVPSLHFYTLNQAGTISKIIDNLEIK
>Q31U46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella boydii serotype 4 (strain Sb227)|TrEMBL
MSFFHASQRDALNQRLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>T0UZ40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HSISS3|TrEMBL
MLALEDMKGLSPHFISVTASNNKYNIKETTVPLANHIQNDLAIPTIAHLPAIYLTKEKVA
DTLRELDAVGVHRILALRGDIIPGVEPLKDFTYATDLIEFIKEKAPQFDIVGACYPEGHP
DSPNQISDIQNLKKKVDSGCSSLVTQLFFDNERFYDFQDKCTLAGIDVPIHAGIMPILNR
NQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYT
MNNAATARHIYNATHALFKSHSNSEK
>A0A3D9ZZS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asanoa ferruginea|TrEMBL
MRRPANTPSRYARPVALGLPSILPGSQPSIGDLVRDEAPTFSFEFFPPKTPEGEVQLWRA
IRELEPLQPSFVSITYGAGGTTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRNVIG
RLAGAGIRNILAVRGDPPGNPNGEWVRHPEGVDYAEDLVRIIRESGDFCVGVAAFPYKHP
RSPDIASDTEHFIRKCRSGADFAITQMFFDGDDYLRLRDRVAASGCDTPILPGVMPVTRL
STIARSEQLSGAPFPAALAEQFARVADDDEAVRKLGIEQASRMCQRLIDEGVPGIHFITL
NRSTATRDVWQNLRVEARV
>A0A257I207|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium BSSC1|TrEMBL
MKVIDHIAQAKETLVSFEVLPPLKGKTINTLYDHLDPLMEFKPSWINVTYHRSETMFKKK
TDGTFERVEVRKRPGTVGICAAIMNHYKVDAVPHIICGGFTKRETEDALIDLDFLGIDNV
LVLRGDAAKNESAFEPEKDGNHYAIDLLRQVSNMNSGIYQDEDIKSGGKTKFCMGVAGYP
EKHFEAPNLEIDLLKLKEKVDAGADYIMTQMFFDNQKFFDFVTACKNMGINVPIIPGLKP
ITNKKQLSVLPRIFHVDIPTDLSNAINKCKTDAECEQVGTEWLIQQSKELKSFGSPVLHY
YTLGKPKVIWNVVKNVF
>A0A562E1L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas taiwanensis J19|TrEMBL
MTPISFEFYPPKTDEQRAQLDRAASRLAAWGPEYVSCTFGAGGSTLSYTADTVRHLNQHH
GFEAAPHVSCVGGSREEIRELLRRYRELGCRRIVALRGDLPSGMGHPGDLRYAAELVQLI
RAEHGDHFRIEVAAYPETHPQAEDALADLRHFKAKVEAGADAAITQYFYNADAYFRFVDD
ARRLGVEVPIVPGIMPISNFTQLKRFSEACGAEIPRWIARRMQAYGDDLAAVREFGADVV
ADLCRRLVAGGAPALHFYTLNLARPTETVLQRLA
>A0A5D3WFF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geothermobacter ehrlichii|TrEMBL
MSRLADSLRTGDFVVTAEVAPPKGADPGRELDLAAAQTGVTAINVTDNQGANMRMSGMAL
AGLMVRRGVEPVLQLTCRDRNRIALQSDLLGAAALGVENLLLLSGDHARFGDHPDARPVF
DLDSVQLLQAVRQLNAGSDMAGRPLSSAPRFFTGAAVAPATRPLELVYQKVVKKAEAGAR
FFQSQAVFDSDAVADFMTLVRPLGVPVILGVLLLKSASMARFLNRCIPGVRVPERLVELL
DRAADPLAEGVAIARDMVGVAREHCQGVHLMLLGREDLMRQILF
>A0A1V6D0L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium ADurb.Bin126|TrEMBL
MSEPISKLQAALAAGQFVVTGEVGPPKGTNVGPVLHEAEEYLKNSVTAVNVTDIQTAVMR
AGSMAFSHMLVDRDIEPVYQMVCRDRNRLALQSDLLSAYTLGIRNVLALTGDHTTMGDHK
EAKGVYDLDSVGLLQAMSILESGQDMGLDMKGNPNKLDGAPRFFKGCCVTPCTDEIEPQI
IKLEKKVEAGAQFVQTQAVYDPAAFEKFMSGIAHLKVPVLVGIVMLKHAGMAKYMNNFVP
GVVVPDWIIKKLSEAAKEDRQKVSIDICGQLIREMKHCCQGAHLMTLGWDMCMPSIVQAA
GLA
>A0A6J0INJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lepidothrix coronata|TrEMBL
MDTRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTK
DDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAADLVKHIRSEFDDYFDICVA
GYPKGHPEAESYETDLRHLKEKVFAGADFIITQLFFRPETFLKFMKDCQAIGITCPIIPG
IFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMV
HGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYI
YRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVF
TCYITGEPNRNGHRVTCMPWNDDPLATETNLLKDQLEKVNRRGILTINSQPNINGKPSTD
PIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQ
PNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDN
YYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A6G9QMB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella aestuarii|TrEMBL
MAFHHAQHSQSLNQSLSELSDINVSFEFFPPSTPEMETILWNSIRRLEPLNPKFVSVTYG
ANSGVRDRTHSVIERIQKETNLLAAPHLTLVDASDEELIELAKHYWNSGIKDIVALRGDL
PEGSPKPTRFANDLVSLLRSVADFDISVAAYPEVHPDARNAQADLIHLKKKIDAGANRAI
TQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVTNFKQTKRFADMTNVAIPQWLSRQFEG
LDNDPGTRQLVGANVAIDMVKVLAREGVKDFHFYTLNRAELTYAICHTLGVRPKP
>A0A7L3FQI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zapornia atra|TrEMBL
MVNETQQSCSASSSSRSDAGSSSGSEGSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITAHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRHEFEDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLR
FMKDCQGIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRSYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A4P9EJC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. SC05B48|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPGTIEHLMKYRPEYISCTYGAGGGNVGANRE
VCQMIRNAGSIPVTHFTVIKNTKEGIRQQLERYLADGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>Q2H0T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)|TrEMBL
MHIREMLAEAERTGNPSFSFEYFPPKTAQGVQNLYDRMERMYNFGPKFVDITWGAGGRIA
ELTCEMVVQAQTYLGLEACMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPPREQEK
WEATEGGFQYARDLVGHIRKTYGNHFDIGVAGYPEGCDDNKDEDSLLDHLKEKVDMGATF
IVTQMFYDADNFIRWVGRVRERGITVPIVPGIMPIATYASFLRRANHMNCKVPEEWMAKL
ESVKNDDVAVRDIGKTLVADMCRKILSAGIRHLHFYTMNLAQATRMVLEELDWLPSPDRP
LKQALPWKQSLGFGRRDEDVRPIFWRNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGVGLTGSNEQNRKKWGEPTSIKDIANLFVRYLNKEIEYLPWSEAPVAEEADLIKDDLIE
LNNRGLITVNSQPAVNGVKSTHPIHGWGPANGYVYQKAYLEMLISPELFPQIKSRIESHP
DLTYHAVTKSGNLHTNAQFEGPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGMEW
ARCYETGTPSRSILDEIMNTWYLVNIVNNDFHRGETIFEVLKGLEAPGLDQVPEPQTNGA
TNGATNGDHNGVQAST
>A0A379BI79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia brasiliensis|TrEMBL
MPFSVEFNPPRDAPAEARLWRAVRQFERMHPAFVSMTYGAGGSTRDRTVRVTGALAQETT
LLPVAHLTAVEHSVAELRSLVGSYADSGIRNILVLRGDPPGDPLGAWQRHPEGVEYAEEL
VRIVRDLGDFHVGVASFPQGHHRSPDLDSDTAFLAAKLRAGAEYSITQMFFDVEHYLRLR
DRVLKFDPVEGAKPIIPELMPITSLRTVARAEELCGRTLPPAVLARLHRAAGDAPDGNPA
AVREAGIEIATEMAQRLIDEGAPCLHFITLNFAKATTEVLTNLGYGVTAAPISA
>A0A1Q9UTL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp. CNJ-863|TrEMBL
MRIAIYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFMPPRDAEGEARLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSIAELRALVGAYADQGIA
NILALRGDPPGDPLGEWIAHPEGVEYAEELVHLIDTLGDFHVGVASFPEGHHRAPDLEHD
TRNLVNKLRAGAEYSITQMFFDVEDYLRLRDRVQAADPEQGAKPIIPGIMPVTSLASIKR
MAELSGSVIPPKVVERFTKAAGDGPEEDRATVRAVGIDFATETAERLIAEGAPCLHFCSL
NFAKATSEVLGRLGVDVDAALHVPA
>M4UBS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia solanacearum FQY_4|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRAILDTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRKEMNDTFHIEVAAYPEYHPQARSSRQDLENFARKVKAGANSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEIPRWIAKRLESFGDDRESIRAFGLDV
VTALCDRLLAGGAPGLHFYTLNAAAATRAIWQRLGL
>A0A848T4W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagales bacterium|TrEMBL
MKITEHLQKAESTLFSLEILPPLRGKSINDLYKVLDPLMEFNPPFIDVTYHREEILYKKR
SDGFIEQIPKRKRPGTVGICAAIHNRYKVDTVPHLVCGGFTKGETEDALFSLHYLEIQNV
MVLRGDALKSEVTFVPSEGGHNYASDLVKQIKDMNEGKFLFEETANEMSTDFCIGVAAYP
EKHFESPNLSTDLKNLKKKVDMGADYIVTQMFYDNQKYFKFLDMCKEEGINVPIIPGLKP
ITTKGQILALPPRFHIDIPEELSNEISKAKDNAAAKQIGVEWAVQQSRELMEYGVPCLHF
YSMSRSEAVTAIAREIF
>A0A7V1Q4E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MRERLLKMLQEGVLVADGAMGTMLQRLGVQAPYELANLMQPDAVRQVHRSYIEAGARLIE
TNTFGANRVKLATHGAGHLVREINLAAVQLAREAAGELPVIVAGAVGPVGKPLAPIGQIA
PQEAGEAFREQIEVLLEAGVDVILLETFTHLDELKIALEQLRTLDSEIPVIAQKAFIEDG
ETLASGLPAQVARTLEEWGVDVIGANCVVGPQRMVGILQAMASATSLPLSVMPTPGLPQY
QRGEVAFEAQPDYFAQYGEQFARIGVNIIGGCCGTTPAHIRAVAERLQGVKPRVRRAPAK
VVEAVKPEELPRAEPSQLAGKLGKKYVIAVELDLPRGLDVAKVLEGARSLKEHGVDAIDI
SDGARARLRMNPIAISHLIQEQVGIEVMMHFACRDRNLLAIQADLLGAHALGIRNILAVT
GDPALIGDYPTATSVFDIDSIGLVRILRRFNEGVDLAGNSIGVRTAFTIAVAYNPLAYDQ
HTEDERLKRKATEGAHLVYTQPIFDIAVLERAVEAVGKVGLPLLVGVLPLRSSRHAEFMH
HEVPGVQIPDAIRKRLAELDDADARKYGLDVAREFALRAQKMTQGIYLMPPFGNHKVAEA
VIDVLTG
>A0A7X9PBL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MVADGAMGTMLIARGFSSDHCLEELNLLHPATIQAVHQSYLAAGARMIETNTFGANRFAL
AEYGLEEKVVRINQSAVRIAREAREVFGQPVFIAGSVGPTGRVLEPFGKLASGEAQDAFR
EQIDVLQAAAVDVVLLETFHNLDEAVLAVRAAKEVGGLPVIAQMAFLEDEQTYAGHTPEQ
VVEALLSEGADVVGANCGVGPEPLRRVLERMRAVAPSARLSAMPNAGFPRQSHRRVIYQT
SPEYLADYAVTFAQLGARLIGGCCGTTPDHIRAMAAAVHAGLPADGIAERSPGPSGESLW
TGDRSVPSAPEVPEPARTELLAKLNAGKFVVSVELDPPKGFNPTKVLRGAEFFRDLGVDA
INVADSPMARVRMGCLAMSALVQTRTGVETIMHFTCRDRNLMGLQSDLLGAHGLGVRNIL
ALTGDPTRMGDYKNATDVYDVDSIGLISIIRRMNEGFDTAGNSIGKPARFTIGCALNPSA
EDLSWELGRFEKKLEAGADFIMTQPLWDIDALWDVLDRIDQRDLKVPIVFGILPLHSSRQ
AEFLHNEVPGMQIPESVRRDIREAGDKALDYGIRQAQDLLFQCRKRVAGVYLMPSLGNYE
VTGEVLKALA
>A0A8J5QEL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. raphani|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDDVKGDDERVKMVGVDIVSELIDKIKTIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A2H9MLX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon CG01_land_8_20_14_3_00_38_12|TrEMBL
MDSFRCSLINTKFPITYEPDSPKGVLVENLPENIPEKVSAICVYNNPRGEPKLDPFVYGL
KLKEKCGKDIIVNIRVQDYSIPLFQSVLWGGHVLGIRNLLMVTGDCCSRSPFLIDVTEGI
TAVTEYLNNGYIMPGLSGKTKIHHNRYKENTSLTDNQQQMFEKFEGKTDFFVGAALLPAR
RKEPEIYQKKIDAGAQFFMTQLTYDSKNIIDFMEKVNPAKPVLVGSGPITSLKRISFFRE
QLKIVGLSDKLIKTLKAAKDIGEKSVEVCVSMYQELRDFARESNYSLGAHVMSIRHPDLA
LEIIRRL
>A0A2E6DSU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MPIFSLSGRLDRSTAAPLRRQLLSDAHFEVIPLKNLTEQLQHLPLGASVSVTASPNKSLD
DTWNLAKDLLVRGFRPIPHLASRMLESRQQLDRLIKELAELGLNELFLVGGDAPLPHGPY
EDSIQVLQAILGLDHKLVHIGVTAYPDGHSFIETAALSNSLRAKQEILKEAGLASHAATQ
MCFDPNTIRGWLESERASGLEIPIHLGIPGAVERKKLLSVGARLGVGASLRYLQKNTGTL
ARMVMPGGYNPNKLLSPLAGDLQRLDVQGLHIFTFNQLEATVAWRNDAISSLKT
>A0A7Y6Y700|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIKKAKGKTLFSFEIIPPKKGNSIQELYDNINPLMEFKPPFIDVTTSREEYVYVE
KNGLLDRKVTRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIQNV
MALRGDAMSHQKYFEVSKGGHQYARDLVNQIQDLNKGKYLHEVIETTDCADFCIGVAAYP
EKHIEAPSLQSDLKRLKEKVDAGADYVVTQMFFDNQKYFDFVDAAKAIGINVPIIPGIKP
LAIKKHLNLLPQVFKIDIPEVLINEVEKCKDNKEVRQVGIEFAIQQSKELLAAGAPVLHY
YSMGKSDNVYAIAKAVF
>A0A4V5TN01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus mangiferihumi|TrEMBL
MGLLEKLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADVIQTN
TYGANAIKLARYGLESRVQQYNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLEEI
LLTVEEQANVLLAGNPDGLLLETYYDFEELSATLKMLRGKTELPIIAQVSMHEPGVLQNG
MTLNQALHELQALGADVVGVNCRLGPHHTIQAFEGVELPDKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVALRDQGVRLIGGCCGTTPKHIAAAKKYLEELTPVEAKYTKPEKVEI
VREAEPATYEPLHEKVKRERSVIVELDTPRHLEIDGFIQGAKKLYEAGADVVMMADNSLA
SPRISNVAMGALLKETHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKIVEIYEATKHLDAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSDDALARMKACGEDKERSTLEGIAIAKELVEVAAEYFNGIYLITPFLRYDMTLELMKF
IGQLDEQKKGVSIDG
>A0A833H1J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptonema illini|TrEMBL
MHRISDRLKKKQPVFSFEFFPPKNDDGERLLMQTIEDLKALEPDFVSVTYGAGGSTRAKT
REWVRSIQDRYAIPAMAHLTCVGSGREEIRSILEDLYSDGIRNIMALRGDPPKGETAFVA
PADGFRYANELISFIRSTGLDFCLGAAAYPEVHGEAPSAAEDLRNLKRKVDAGADFLVTQ
LFFDNEKYFSFVDQVRAAGIEVPVVPGIMPITAFKQIERFTAMAGCAIPEFLVKSLAGVQ
DDAEALLNLSLEFTLRQCEELLSKGAPGIHFYTLNQSRATAIILDRLRRSVSAERR
>A0A7X7A599|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MDLHQLLKEGVLVTDGAMGTLLEERGIPQGRAYDLANLTHPSLVQSVHEEYIDAGARLIE
TNTYGANRFKLAPHGLGDQVAEINRAGVEIARRAAGDRALVAGAMGPIGRHLVPVGKITH
AEAFRAFTEQAQALLDAGIDLFVLETFADLEELHLAVDAVRSLCSHPIIAQKTFIEDGET
LAGGLPRRVIEEVSRWDIVAFGANCTVGPQRMLSIIQEMAEHSPLPISAIPTAGLPHLIG
GRVAYDATPEYFARYGRQMVEAGARIVGGCCGTTPAHIRALAQAVRGVEPGSRRVAVSVR
TRSDETKATRQAQASRLAEKLGRKFVVTVELDVPRGLDMSSLIQAAEALRDQGCDCINIS
DGARARLRMNPMVVGRLVQEIVGIEVIQHFACRDRNLLAIQADLLGAHALGLRNILAITG
DPTQVGDYPTATSVFDVDAIGLVRILRAFNNGVDLSGTSIGEKTAFLIAVAYNPLARNPE
EEADRLRRKADEGAHFIFTQPIYEMSVLEIAVREAERVGLPLLMGVLPLRSSRHAEFFHN
EVPGIQIPEEMRRALAELEGDDAKRYGIEQAQQFVRRAKGMTAGMYIMPPALSPHVAGQV
MEALH
>A0A7Y2J6P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIAKAKGKTMFSFEILPPLKGQHIQSIFDNIDPLMEFNPPFIDVTYHREEYVYKE
LEDGLLKKQVVKKRPGTVGICAAIQNKYGVDAIPHILCGGFSQEDTENFLIDLDFLGIQN
VMALRGDPVKSETYFRPEKDGNVYASDLVKQIQDLNLGRYLDEELQNTSKTDFCIGVAAY
PEKHLEAPSLDSDIHFLKKKIKKGATYIVTQMFFDNQKFFAFEKKCRDEGITVPIIPGLK
PIATKKQLNMIPQRFNVDLPDELILEVVKCKDNNEVRELGVEWCIAQSNELKAAGIPVVH
YYSMGRSDNIKAIASQVF
>A0A7V1EID8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-3 bacterium|TrEMBL
MLRDKMKHKKIITLEVLLPTSIDIENLIKELRVFREYTDALNIPSNPLGKLRPDSLCFAH
ILQERVKIETIPHFVARHFTLLSFESQLLGAKALGVENILCVTGDSPVEGRSMFELNSAK
LLDVAKNLRQGLTSARNTITPIDFCLCTSFNPNVPNLQGELIKTGEKCRCGAEVFFTQPV
FQPERFIETLKELRRRHPDIKIVAGLSFLYTKKRAFSLMKFLGIPYQYITKIEEVNESEL
LLETAKKLKDYVDGFYVIPISKYANAINLVRQIRQIL
>A0A2E6EVQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVVDHIKKAKGKTLFSFEILPPLKGQNIQSIFDHIDPLMEFQPPFIDVTYHREEYVYKE
LSGGLLQKKVVRKRPGTVGICAAIQNKYEVDAVPHILCGGFTKEDTENFLIDLDFLGIDN
VLALRGDAVKNETYFSAEKEGHTFAKDLVKQIVGLNKGEYLDEELLNKSKTNFCIGVAGY
PEKHMEAPSLDQDVLRLKEKVAAGACYIVTQMFFDNQKYFEFVDKCRTAGITVPIIPGLK
PLATKRQLSILPHRFHVDLPDTLTLEVLKCKTKDQVRQVGVEWCIQQSRELISAGAPVLH
YYSMGKSNNIHKIASELF
>A0A2G2R1P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robiginitomaculum sp|TrEMBL
MIIEETRNNRDFHRNGHRPVPGTLARASSSGGEHINISFEFFPPKTEKMGEALWQSIQKL
ESLNPDFVSVTYGAGGSTRERTHQTVARIVKESSLKAAAHLTCVGSDKAEIDEIAREYWQ
AGVRHIVALRGDPVGGLGAPYVPVDNGYAYASDLVTGLKNVADFEISVSAYPELHPESLN
WDDELDNLKRKIDAGATRAITQFFFSADTFMRYLDKALDAGISIPIIPGLMLQPNYRGLT
RIAKLCYISIPDWYHNLFEPLDDDPQTRLLLTASTAADLAAQLRAQGVEHFHFYTLNKAD
LAFTTCQILGVKAQNTRAQKVVT
>A0A5E4U4N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea commovens|TrEMBL
MNGSDDNKTIMTQPSFSFEFFPPKTADGAEKLRATREQLFPLGPKFVSVTFGAGGSTQQG
TLDTVIEIQREGVDAAPHLSCVGSTRDNIRDILTTYRDHGIRHIVALRGDLPSGMGEIGE
FRYASELVEFIRAETGDWFHIEVAAYPEYHPQAKSPRHDLEHFANKVKAGANAAITQYFF
NADAYFRFVDDVARLGVNVPIVPGIMPITNYSQMMRFSEMCGAEVPRWIAKRLEGFGDDR
EAIRAFGLDVVSALCERLLKEGAPGLHFYTLNAAAATKAMWQRLGL
>A0A3D0TYJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MVPAGRGRRRTKRGNAAGGAGAGGAADRAGARAHSRLLSTVRWELIPLKNFAEQCAFLPP
GSTVTVTASPNKTLEDTLDLCEQLGAAGHKPVPHVAARMVRSRGHLAELAARIAALGMDE
IFLVGGDQPEPAGAYAAAVELLEDLLTHVAAGAPVLTRIGVPSYPDGHALIADDDLRGAL
LRKQELLAAAGIASHAATQMCFDAAKIVAWLRAERAAGLRLPVLIGI
>A0A532VIQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium Ae_b3a|TrEMBL
MSFSDALKGGKFLITTDVVPHKGTGVSKMLSRVDSLLGKVDAVNVADLPSSAMRASSFSI
ALLLMKRGLEPILQMTCRDRNRLALQADLLGAYILGIKNILALTGDEMELSDDLKAKPVF
DLDSIGLLKAARKLEKGYDLADNPLRGSPKFCMGAVLDPGAEPIEPEIERMQQKVKAGAE
FFQTQPIFDTRVFFKFLEKVGKLEVPILGGILLLKSAKMAQFMNENVPGVSIPEDFTHQM
KKTEDPVQTSIQIASGIIEQIRGVCGGVHIMTVNWENKVPMVLKSAGLRTY
>A0A4Q7YK89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. BK022|TrEMBL
MALGTASTRTDRARTVRDILATGKTAYSFEFYAPKTPQGERNLWNALRRVEAVAPDFVSV
TYGAGGTTRATTVKETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPDSYLRLRDRVAAAGCETPVIPEILPVTSVKMLERLPKLSNALF
PPELKERILAAKDDPAAVRSLGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHQPPRA
>A0A2A4NTJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIEQAKGKTLFSFEIIPPQKGQNINDLYANIDPLMEFNPPFIDVTTSREERIYIA
KGNGLLEQKITRMRPGTVGICAALKYKYNVDAIPHVLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKHEQYFKPVDGGNEYAVDLVSQISDLNKGKYLHEIIETPHKANFCIGVAGY
PEKHMESPSMDADLRRLKQKVDAGADYVVTQMFFDNQKYFEFVRKAKEIGINVPIIPGIK
PIAISRHLQVLPQVFKLDLPDVLVREIEGCKNNKEIRQVGIAWAIQQSKELIQAGVPVVH
FYSMGKSSNIYTIAKEVF
>A0A1Y3M423|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter agilis|TrEMBL
MTLKKRAAVPPSLSYELYPPATPEAGEAVLRTIDELEATHPDYVSVTYSGTPARRRASIE
LIGHLTSNTRLRPLAHLCCVGETRESLDLLVRQFVALGVRGVLALRGDLPRDPQAFRGEL
PFAQSLVELIREVEARHGATLAGGRLAVGVAAYPNRHPESPSFLHDVEVLVSKQRSGADF
AITQVYFDPAHYVRLVTAARAAGVTIPIIPGVMPLGNIRRLERLAGMTGVRPDTALLHRL
ETAAGEAERRRIGVQAAAVLARAAFEAGAPGVHLYTFNDHRASIEVIEEIDLPAARTPAA
VPA
>A0A2L0UB89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter agilis|TrEMBL
MTDLPVRVEVIPSEGIADRLREHLPAPAALTVTCLPHHGPREAVGLAVDLARAGYTAIPH
LAARSVTGRTELAGYVERCADAGIGDVFVIGGDATAAAGPYAWSGALMEDIADLSGGVLR
MGMAVYPEGHPGATDEELVRTMLAKQPFASWCVTQLCFSPDTLRGYPSRLRLQGVGLPVW
AGVPGPVRMARLVRLAGRIGVGQSLGFLKRSAGASNSGAAVRQLLSSASYDPGPLVGAVR
ASGYAGLHLYSFNDLAGLAQSGPASAAG
>A0A4Y9NS98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium frederickii|TrEMBL
MSGAMTDVTTPATADGHLKQPAISFEFFPPKTEEMERNLWDTINRLAPLEPKFVSVTYGA
GGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPV
GGIGTPYASHPDGYQNSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVD
AGATRAITQVFFDNDLYFRYRDRVRARGINIPIVPGIMPMHNFKQARNFVTRAGTTVPDW
FAAKFEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRA
KSVQKAA
>A0A1Y3YDB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. An46|TrEMBL
MKITELFERGEFVVSAEVGPPKGFHVEHLLEEAKTYLSGITAVNVTDNQSSVMRLGSLAM
CKALKDEGLTPIYQLTCRDRNRIALQSDLLSAAMFGIENLLLLTGDHTKLGDHPQAKPVF
DLDSVSLIHAVKKLEEGVDLGGNELIGEAPKFAKGAVVSPCSDSVDAQLAKMERKVMAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKKDKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKVPELLKAAGI
>A0A7M1B981|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas paralvinellae|TrEMBL
MFDTLIEKLQNNTYITLETTPGHSAKFTPIIDKIESLGLHTMVDGFSTTDNPLAKLKFNA
LFGARLLQERFNKPVIATMSMRDRNKIALQSDLLGANEFDIRAILALTGDPANISDQPNA
KGVFEADSTLLLDIISAFNSGMDYSAKPFKERPLQIYPFAVVNSYAKNPKTLQKKMQKKI
KHGALGIITQPVYDIENAKQLLELKEKANKECCSENKSAELIMGVFPITKLRTAQFLASH
VPGINVPPCWLDKLREANAKGAQEEYKIGFELSKKLFEDLKALHPKIHLMTANQFQIAKD
ILV
>A0A6G0RAD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora fragariae|TrEMBL
MPRVSSIHVTKQKERHEEADELAATKFVLDDSTVWTGLSTEDTRAAGESEGDQERLLQRL
HLVQGLLTFVRMLRRSRGLQAEEEDDEAKTSAQWTPEWASLKRALGLQRLKAKQDAGADF
IITQFFFDVDMIHWIADCKDAGITILPGYLSIQNYSSFCKFTSWCKTRVPESVLAALDTI
KNDDAAVRRYGTQLAAETCQRLLAAGVNSLHFYTMNLPRP
>A0A8J5DYM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nymphon striatum|TrEMBL
MPRPSVSFEFFPPKSVQASFRLWDCVRTLSPLQPEFVSVTYGAGGTTRQLTHEVVAAIGQ
STDLNVAAHLTCVDATRAQTLEIAETYRAAGVNHIVALRGDPPKGTDHYRPHADGFDGAI
DLTRALADGGFDVTVGAYPETHPDATNASACIDHLKAKIDAGATRAITQFFFEADTFLRF
RDACAAAGINAPILPGILPIENWSGVQKFAQSCGAAIPQVLRDAFGKATPENRDLLATAH
ASELCDTLLCEGVEHLHFYTLNKPELDPRCVSRLGPCPRTQPSKRRLTCRRQRRGIRVTF
TDRWVQLFRWIAPDHTARAG
>A0A417MV67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. TF08-15|TrEMBL
MKIRDILNKDTATISFEVFPPKKSTDFGNVEVAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGEIQKQHNVPTVAHLTCVCADRSSIGAALTEMQAVGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKENGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIIPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNLSEILKA
>A0A0P0EAR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus gallinarum|TrEMBL
MYQTREQVLNLLDNLSEFNVKNILGLRGDKIPGKQPVGDFNHANDLVAFVHQNRPDFSIA
SACYPNCHPEATGFVDDIAHLRTKVDAGADHLISQLFFDNQAFYDFQEKAEIAGIHVPIE
AGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSKEAMREAGIAFAVDQIIDLVSEG
VDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHRLLVHVLTN
>A0A328M8E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. SRB_336|TrEMBL
MPAISFEFFPPKTDEQRAQLDRAAQVLKVHRPDYASVTFGAGGSTLSYTGDTVARLHKQH
GLHVAPHLSCVGGTRAELAALLDGYRAAGYRRIVALRGDMPSGMATAGDFRYAAELVQFI
RAHSGDHFHIEVAAYPETHPQADDALRDLLHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VQKLGVNVPIVPGIMPISNYSQLKRFSDMCGAEIPRWIAKRMQAHGDDAESVRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRARATQLVLQQLF
>A0A413ALE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus asini|TrEMBL
MSHASLSFEIFPPNTHVGEEKLLGTLEQLGDLAPDFISVTCSNNKRNIEETTLKVAGYVK
NHLQIPTIAHLPACYLSKQQVTDILTQLDQLGIKQVLALRGDIDPQIPPTKDFSYASDLV
AYIKEAAPHFEISGACYPEVHPESKSHVADVLHLKEKVTNGCDQLISQLFFDNEVFYRFL
ESCQLANIQAPVLAGIMPIVNRKQALRIIQTADAKLPKKFLAILDKYEHDPVALRDAGLA
YAVDQIVDLVTQDVAGIHLYTMNNAATARQIYQATASLFHKTPVLDQVLG
>A0A1D7YGV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces fodineus|TrEMBL
MALGTSSTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPTGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVTHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPKLSNAVF
PDALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A150R6Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
MVSKSKMERLLSERQFLVSAELTPPRHYDLEKLLKHARNMAGCVDVVQINDHLLSQARCA
NMAVGHFVKQEGLEPVLQFSLRHKNRIALQGDLLGMAALGLSNIIILGGYPCAIGSDPEA
KEVSDVDSYAAIELTRRMTREGRLYNGDVISPAPYFHVGTIDFPCGEQAIAGAMDRLSAK
IDAGASFIQVQAVFELAPMRRWMAAVVERGLHERAHFIAAIFPFAGVDRLSFLQKVPGLV
VPEHLIERVRQSGDAEGESYRITLELIRGLRDIPGLSGIHMRSIGAEDWVPRLVEEAGLR
RAT
>A0A3B0QV42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKKANGETQFSFEILPPLKGQHIQSIFDNIDPLMEFKPPFIDVTYHREEYVFKEQENGLL
KKQVVRKRPGTVGICAAIQNKYKVDAIPHILCGGFTKEDTENFLIDLDFLGIQNVMALRG
DAVKSETYFKPEKEGHVYACDLVSQIEDLNKGVYLDEDLQNTASTNFCTGVAAYPEKHME
APSLESDIHFLKRKIKNGATYIVTQMFFDNQKYFDFVDKCRKEGITVPIIPGLKPIATKK
QLNLIPHRFHVDLPEALIMEIVRCKDNAQVRQVGIEWCVQQSKELQKAGIPVLHYYSMGK
SDNIKAIASQLF
>A0A3B0Y704|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKTQQKLEQNFSCEFFPPKTELGMEKLLATAETLKLEIKPSFFSVTFGAGGSTRETTFNA
VKKVKQAAGCEVAPHLSCIGSSKQQLSDILDEYKQQGIKRIVTLRGDMPSGTVSHSDFNY
AYQLVSFIRENYADQFHIEVAAYPESHPQSDNAHKDLLHFKEKVDAGANSAITQYFYNID
SYFYFVDSCEKSGMDIPIVPGIMPITNYSNLSRFSDMCGAEIPQWLRKKLESFADDTDSI
KEFGADFVSAMCEKLLAMGAPGLHFYTLNQSDATMRIWNNIRP
>A0A3B0UWT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MGLLRRLQNHPAFLEKMYDLTHTGVYKLHPLIKKLGYQRANRWLRGGEEITKRAVFDCRM
CGQCVLHSTGMTCPMSCPKNLRNGPCGGVRANGHCEVLPEMKCIWVEAFERSQQMPVYGN
EILHIQ
>A0A521B8C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp. DSM 26295|TrEMBL
MSKRISFEFFPPKTEQGREKLLNTQQKLLAKKPEFFSCTFGAGGSTRDYTRQMVDLLREQ
HADTAPHLSCIGQSRDEIMELVNGYKESGVRRIVALRGDLPSGMGYAQSEVKYADDLVAL
IREETGDHFHLEVAAYPENHPQSRSFDDDIAHFQRKIRAGADSGITQYFYNADAYGYYMD
ELRRRGCDAPVYPGVMPILNVANLFRFSDNCGADIPRWLRSRLDDIRDDEQAVKAFGEEV
VTRLCERLLAMGAPGLHFYTMNQSGPILRVLDNLGL
>A0A3B0YYR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
METQKQHPRVYSFEFFPPKTGAGAENLRLTRDRLAALKPRFFSVTFGAGGSTRERTFETV
CEIQRNSGIEAAPHLSCVGSTRDSIRNILSLYKNEGIRHIVALRGDLPSGMGQAGEFRYA
NELVEFIRAETGDHFHIEVAAYPEFHPQASNAAADMDNFQQKVEAGADSAITQYFFNADA
YVAFVEQSEKRGLSLPIVPGIMPITNYSQLARFSDMCGAEIPRWIRKQLEGFGDDTASIR
AFGEDVITRLCQTLLDAGAPGLHFYTMNQSKPTTAIWHNLGLGSD
>A0A1T5P606|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga ginsengisegetis|TrEMBL
MKVTEHIAKAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPAFINVTYHRSEHMFKKK
ADGSFEKVEIRKRPGTVGICAAIMNHYNVDAVPHLICGGFSREETENALIDLNFLGIDNV
LVLRGDAPKNETFFEPDPHGHSYAIELLDQVAHMNNGVYLEDDLQSGVKTNFCIGVAGYP
EKHFEAPNMQTDLSHLKRKVENGADYIVTQMFFDNQKFFDFVNKCREMGITVPIIPGLKP
LTSRKQMTMLPRIFHVDLPTDLSTEILKCKTDKDVELVGTEWLIAQSKELKAFGVPVLHY
YTLGKPKVVRQAVEAIM
>A0A3A1NDX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda maritima|TrEMBL
MKITDHIKKAKGDTLFSFEIVPPVKGKSIQELYRNIDPLMEFKPPFIDVTTSREEYIYKE
KDGLLDKKLTRTRPGTLGICASLKHKYDVDTVPHVLCGGFTREETEYLLVDCQYLEIENV
MALRGDARKEEKYFIPTQGGHQYAAELVKQIHDINQGNYLHEVIEGHEMGDFCIGVAGYP
EKHMEAPSLQSDLKRLKEKVDLGADYVVTQMFFDNKKFFAFVEAAREMGIDVPIIPGIKP
IAVKQHLQLLPQVFRVDIPQDLIEAVEGCKTNQDVRKVGVEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKDIAKEVF
>A0A364RJ67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter arcticus|TrEMBL
MKITEHIQNATSTLFSFEILPPLKGENMKALFSNIDPLMEFKPPFIDVTYHREEYVYKTH
ENGLLEKRTTRKRPGTVGICAAIQNHYKVDTVPHLICGGFTKEETENALIDLHFLGIDNV
LALRGDCVKSEQRFIPEADGHHYASELIGQIVEMNNGSYLDKEQVYNSGTDFCIGVAGYP
EKHFEAPNLKSDLRWLKKKIEMGADYIVTQMFFDNRKYFDFVNLCRSEGINVPIIPGLKP
FTTKTQLNVLPSLFHIEIPYDLADAVENCRDNKAAAQIGVEWAIQQSKELIAFGVPCLHY
YSMGKSETVRKVAEQLF
>A0A0C4USH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria bernieri|TrEMBL
AYGIHLGTEMCKKILAHGIKTLHLYTLNLEKSALAILANLGLIDMTKIKRPLPWRPPANV
>A0A7S1H4C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hemiselmis andersenii|TrEMBL
GVCGGAEAFYALEFFPPNTPDGARNLISRVDRFGQAASPPLWVDVTWCLNSGKRAMETLV
AAKAVCGLSVQLHLSCTGLTRDMADGVLEDCIEAGIFSLLIIRGDPPPGSDQWVQTDGGF
ATARDLVAYIRRKHANAFSIAVACHPGGLPGGGDSVQNFKSKIDAGADYGVCQLGFDTSA
YSDFVKGCKGAGITAPIIPGVLVPPPSPAQVSSVCKHCGVPP
>V6IXY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporolactobacillus laevolacticus DSM 442|TrEMBL
MRAPLLEELNKRILIGDGAMGTLLYSYGIDRCFEELNVSQAEEVRHVHEAYINAGADVIQ
TNSYGANRIKLARYGVEHEVTRFNRASVQLAKQAARPETYVIGTIGGIRGFQKQSVELQE
IRAGFREQADALLSEGVNGLLLETYYDFDELREVLQIARALTDLPIITHVSMQEPGVLLN
GMTLSQALKNLEELGADIVGTNCRLGPFHMIEALRGIPLPKKAFLSAYPNSSLPDYREGK
LHYENEPEYFKKYAVEFRNEGVRLLGGCCGTTPIQIQAFKQGISELEPLESKVVTLHQEV
IKVSNSGDVPESSLYNKVLTGRSVFVEFDTPRHLNTANFFKGVKALQDAGADAITMADNS
LASPRISNAAIGRLIKDRFDVPPLVHLTCRDRNLIGLQSHLLGLHVLGLHNLLIVTGDPT
KIGDFPGATSVYDVSSMELIKLIKRFNEGISYSGKSLKQPTHFRVAAAFNPNVRNLERAV
QRLERKAECGADYFISQPVFDKERIIEISEATREVSAPIYIGIMPLTSARNAEFLHNEVP
GIRLPDDVRARMAAARDKEEARRVSLDIARELIDTAMEHFRGIYLITPMGHYTMSVELIK
YIKEKESKLAVQANGAGVTL
>A0A7K3HG25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5475|TrEMBL
MALGIPSTRTDHARTVRDLLASGAQSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGSSRDGTVRATERIATETTLTPVAHLTAVNHSVAELRNVIGSYAGAGIRNMLALR
GDPPGDPMGEWVPHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSPDWESDIRHFVD
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSMGIEYATELCARLMGEGIPGLHFITLNHSTATLEIYENLG
LHQRPR
>A0A7S1E7K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hemiselmis andersenii|TrEMBL
PGGGGGLLEGFSIEVTVKGASTIQDFSKILPPGTSVFIAALADTSTTDIAALCARLKRDG
MLPVPHIAARAVGSAEALEETVRGYAAAGVEHVLLISGDVKTPLGPFASAVDVCRTGVFE
RHGIKQVDVAGHPEGSASIPDAAGALREKVEWAEKAGVRMDIVTQVCFDAGTIVEYVASL
RGGGIGNAVRVGVAGPVKMSNLVRLAGTLGLGPSSQLIMSQPGLVAQVATLNDPSALLSS
LGGSKLGEGSLGEAGVHVYSFGGIELSAAWASGSPP
>D7LKW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabidopsis lyrata subsp. lyrata|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFGCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIGENGLASNEAYQSDLEYLK
KKIDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYRGFLRMTGFCKTK
IPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKMLAHGVKSLHLYTLNMEKLALAILMNL
GMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALSDHQFSRPRARDKKLEQEWVVPLKSVEDIQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLVKINSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLD
AVVEKCKALPSITYMSVNKGENWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDYINGNIFAVFADI
>A0A352QRZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenimonas sp|TrEMBL
MTQLSFEFYPPKNDEQRAQLDRTVRKLKAHQPEFVSVTFGAGGSTLSYTPETVRGLRQDH
GLNGVPHLSCMGGTRAELRELLNLYRALGCNRIVALRGDLPSGMARAGDFRFAADLVAFI
REEHGDHFRIEVGCYPEFHPQAEDALADLRHFKAKVDAGADSAITQYFFNADAYFRFVDE
VRAAGVSIPVIPGIMPISNYSQLRRFSEACGAEIPRWMARRMQAFGDDAESIREFAADAV
AAMCRRLLEGSAPELHFYTLNLAKPTEAVLSRLR
>A0A1G8CIP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas benzenivorans|TrEMBL
MSQERRYSFEFFPAKTEAGHEKLLNTARQLAAYKPDFFSCTYGAGGSTRDRTLNTVLQLN
DEVGVSTAPHLSCVGDSKAELRELLTRYKDAGIQRIVALRGDLPSGMGMASGELRYANEL
VGFIREETGEHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGASSAITQYFFNADSYFY
FVERVRKLGVELPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDSDSIRAYG
EQVVSEMCERLLQGGAPGLHFYCMNLAEPSLAIWNNLKLPR
>A0A323TV35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEIGD
FNYAKDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A1E7K2Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces qinglanensis|TrEMBL
MAIGISAPRTDRPPTVRDLLASGEQSFSFEFFAPKTAKGERTLWDALRRIEAASPTFVSV
TYGAGGSSREGTVRNTERIANETTLTPVAHLTAVSHSRAELRNVIGQYAAAGIRNVLALR
GDPPGDPLGEWVKHPEGIDYASELVELIKESGDFCVGVAAFPEMHPRSTDWDSDIRHFVN
KCKAGADYAITQMFFQAEDYLRLRDRVAAAGCSTPIIPEIMPVTSVQQIERFAQLSNATL
PAGMIERLHAVRDDPAAVRSVGIEYATDLCARLLAEGVPGLHFITLNHSTATLEIHQNLG
LRERATLGLRKA
>A0A0R0D2D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas terrae|TrEMBL
MPSLSSSLTDAYSLEVSTKAIPALIAAAPRIAAGTSIFIPYLAGENDAARLRAAATVRGL
GFEPMPHVPARRITSLEAVESFVTRAASEAGVERCFVIAGDSPSPKGRFADSASLIETGV
FERAGIKHIGVGGHPEGHPVMSVAARWQVLARKCDSIESCGMSPLIVTQFGFDADVVLSW
LEELRQRGIQHPVRVGVPGPASVAALARYAAMCGVSASESVWSKYGVSIGKLLGAAGPDK
FVDRLASGLTEAHGEVSLHFFPFGGIVQTLEWMELYRARGHSRHA
>A0A1E5D3F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio genomosp. F6 str. FF-238|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELINIADDYWNNGIKNIVALRGD
IPAGGGAPDMYASDLVKLLKSQHDFDISVAAFPEVHPEAKSAQADLINLKRKVDAGADRA
ITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQASRFAAMNNVKVPGWMAQQFN
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPA
>A0A0K6IX42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidiphilus thermophilus|TrEMBL
MQHLELSVEFFPPQTAEGEAKLDEARQRLMQRLRPAYYSVTYGAGGSTRERTFAVVERLH
RAGLDVAPHLSCIGASRAQIREILQQYQALGVRRLVALRGDLPSGVRDPGELRYASELVD
FIRAETGDHFWIAVAAYPEYHPQAASALADLDAFARKMHAGADCALTQYFYNPDAYAHFV
EESRRRGVTAPIVPGIMPITSFARLARFSDACGAEIPRWVRKKMEAYGDDAESVRAFGLE
VLVRLCERLLQLGAPGLHFYTMNQAEPTLAIAEALGLTRCATS
>E6WQA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas suwonensis (strain 11-1)|TrEMBL
MTPISFEFYPPKTDEQRAQLDRAAARLATRSPEYVSCTFGAGGSTLSYTAETVRHLNQHH
GFDAAPHLSCVGGNREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYAAELVELI
RAEHGDRFRIEVAAYPETHPQAEDALADLRHFKAKVDAGADAAITQYFYNADAYFRFVDD
ARRLGVEVPIVPGIMPISNFTQLRRFSEACGAEIPRWITKRMQAFGDDAVAVREFGADVV
ADLCRQLVAGGAPGLHFYTLNLARPTEAVLQRLA
>A0A2T5KS47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GV085|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLAEYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWRNLKLPR
>A0A1H3VQI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromusa kysingii|TrEMBL
MNVIEIINNSDKTVFSFELLPPLKGSDTGKICRTIESLVDYAPQYINITTHRDEMVFVEL
ENGSIEKRVVRKRPGTVAIASAIQHKYGIPVVPHILCGGFSKSETEHVLIDLNFMDIHNI
LALRGDGLKTDHVFRPNADGHANAAELVEQVVNLRSGKYLEPDLKNTAPLNFCVGVAGYP
EKHFEAPNFDTDLNYLKQKVDAGADYIVTQMFFDNQVYYDFVAKCRAIGINVPIIPGIKP
INLTNQLTVLPKLFSINLPQDLATELGKCKNNDAAKQVGTEWAIQQSKDLVAHNVPSLHI
YTYGVSDNTRKIVEAVF
>A0A3M6DGU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. papulans|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLTQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1G5S5C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidaminobacter hydrogenoformans DSM 2784|TrEMBL
MKIKDMLIATRPTVSFEIFPPKANYPIETIYETIEALKDLRPDFISVTYGAGGTSQDNTI
EIASKIKNTYGIDSIAHLTCVTSSKSSMIETLEKIRSSGIENILALRGDIPQALLDDKTW
TPEYRYAYELIEDIHKFDNFSIGGACYPEGHIESRNKIDDLKNLKFKTQKGLDFLITQLF
FDNELFYQFREKMELLGIKTPVLAGILPVLNINQVIKIQELSGCNLPPKFMRILNKYEHN
PEALQEAGIAYAVDQIIDLMSSGSVDGIHLYTMNRPEPTRRIMESIGTIRRALSTRREG
>A0A4R0J1R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella speibonae|TrEMBL
MANGLPSTLPGGAPTIRELLASGDRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWVAHPEGLNHAIELVELIRSLGDFCVGVAAFPDKHPEATSLEADAQVLAA
KAQAGADYAITQMFFGADDYFRLVDRAAALGCDIPVLPGIMPVTNIKQIQRMADLTGMAL
PAAVTDRLHAVEDDPAAVREVGVEIATELCERLLAGGAPGIHFITLNRSTATRQVFRNLK
ASVVS
>A0A6H1RG48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora sp. ASAGF58|TrEMBL
MNANAERLEQYLMNARFEVLPLRGAVERAEQLPPGTTVTITSSPTKGTEATLDVAAQLLG
RGLHAVPHLAARLIADTAHLTALLDRVDALGLSEVFVVAGDSPHPRGEFPDALALLRAMD
ELGRRPARVGITGYPERHAFISDASTIRAMTEKSRYADYVISQICYDPHTVASWVKDVRA
RGLALPIYIGVPGVVDAHKLLRISLKIGLGDSMRFLRKQHGVVSKLLTRYTPEELFDGLS
PYLVDTTCGIAGWHFFTFNEIAKTVQWRHDLVARLREVPA
>A0A7G3E4B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. 71-23|TrEMBL
MTSSVDSVPAPAPFSFELYPPRTAASEAALHETIARLAEVGPRFISVTYGAGGSTGGRSL
EVLRHIRATTDVEPLAHLTCVGNTYAGANRLIREFLDAGIRSFLALRGDPPAGTSEDDVY
LGDLESAAQLVQLIDRVQAERAPYQESGIPGMPGAARVDPRPRVDIAVAAFPNGHPRSRH
PREHIDALLAKQAAGATLAITQLFFHADDYVWFVDRARTAGVTIPILPGIMPITGPARLR
RVLQLTGEEIPADLAIALEVEPTAEGQREIGIAHAARLAEEVLAGGAPGVHLYAFNNHDT
VLSVLREAGILTAGASGPASTPVKESRR
>A0A494Y8T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararobbsia silviterrae|TrEMBL
MASCELSFEFFPPKTADGLDKLRATRAQLAALNPKFVSVTFGAGGSTQQGTLDLVVEMKR
DGLEAAPHLSCIGATRESIREILKHYREHGIRHIVALRGDMPSGMGEIGEFRYASDLVEF
IRAETGDWFRIEVAAYPEYHPQARSPKHDLDAFARKVKAGADSAITQYFFNADAYFRFVD
DARALGVEVPITPGIMPITNYSQLLRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTDLCERLLDHGVPGLHFYTLNAAAASRAIYERLRNKD
>A0A416EC47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnotalea sp. AF33-28|TrEMBL
MKIRDLMKQKEITLSFEVFPPKTADKYASVEKAVTEIARLSPDFMSVTYGAGGGTSRHTV
DIASAIHRDCGVPTLAHLTCVSSTRENIRQMLDTLKANGIDNILALRGDIPKDSDFPMPH
HYHYASELIQDIRSYGDFCIGAACYPEGHVESANKKEDLLHLKEKVDQGCDFLTTQMFFD
NNILYNFLYRIREIGITVPVCAGIMPVTNGRQIARICQLSGTYLPARFKAVVDRFGDNPA
AMKQAGIAYATDQIIDLIANGVNNIHVYSMNKPEVAAKIMENLGAIYESQL
>A0A0F0HM63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix sp. ST-888|TrEMBL
MREQEAPGGSLRAALASGEPTISFEFFPPKTDAGESALWQTIRRVEAVAPTFVSVTYGAG
GSSRARTVQAVEGIAEQTTLRAVAHLTAVGHSVAELRSIIGRYADVGIRDVLALRGDPPG
DPRGPWTPHRQGFSHAAELVQLVKECGEFSVGVAAFPELHPRSPDWDSEIRHFVAKCRAG
ADYAITQMFFDVEHYLRLRDRVAAAGCDTPIIPEIMPATNAAQIQRFAELSNATFPCGLT
ERLEAVRDDPGAAHRIGVEHATRMARRLLAEGAPGLHFITLNRSTAALEIYRNLDLPRGA
VQSSKYRAAASAFAAA
>A0A2N6CLL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
EGLEDDRDTRRMIAANVAIHQVRQLQREGVEDFHFYTLNRSQLTFAICHSLGVRPVPAAI
AAG
>A0A421JF46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Meyerozyma sp. JA9|TrEMBL
MSVVQKINSLGPSDRFISFEFFPPKTDTGFRNLLARLHRMSALNPLFITVTWGAGGSTSE
KSLDLAITCQKELGLTTVLHLTCTNTNKEIIDNALQRARENGIRNILALRGDPPRTEEYW
TPDCDFYSAVDLVKYIKQQHGDYFCIGVAGYPEGHVEGSDTSNQNPEKDLPYLEEKIKAG
AEFIITQLFYNVDKFMHYQKLLSSSPILKNIPLIPGLMPITTYKVFTRASKLSHSSIPHE
IESQLQKTSSDDNAVKSIGIRIITDMVDRINSRSNGAIRGYHFYCLNLEKAVASVLDQSA
VLRPIMEAPSTTVSHDDAVASDDEDIEVPPKKGRRRSSVINENEVAAPGFAAVGMGHKAA
ANKALLSDKRTLVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPSLKIHSPQ
EAIAKWGTPESTKDISKVFLNYLSGKISILPWVDAPLSPETALIQEELFQLNDKGWFSLA
SQPSVNGVRSSDKIFGWGPSNGFVFQKSFVEIFIPKQEWSTKLYPKLKHMIDSLDITYYA
GDSSGEIQSNLPVGPDSHNSKNAVTWGVFPSQEVLQPTIIDIESFRAWNEEAFHLWSEWA
RCYKKDSVSYNLLNSINGDYYLVSLIYHNFNDETGLWRALLE
>A0A7K1VL52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. VKM Ac-2803|TrEMBL
MTRARFEIIPTDDIGDTAARAFADPSRVTLTVTSLPKHGTERTIESALELAGRGFRVVPH
LAARNVGGRSDLERTLGRLLDAGIDEAFVISGDATTASGAYTTSLELIRDIVAIAPGLAL
DIAGYPEGHPRLSDESIERHLEERAPFIRSIVTQMCFDVDAVVRYADGLRSRGIGAAVWA
GVPGPVERTRLLSLGARIGVGSSLGFLKRSSSVAGGLLRGRRFDPTAFVARLEAAAGDRL
DGLHVYTFNELDGLDAFLG
>A0A1F9PC96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium RIFOXYA12_FULL_46_15|TrEMBL
MNKVVDMGLNEKCYILAGVTPMKNAGMANFMSKYVPGMDIPESLIKRLKGVDKKDQAEEG
IKFALEQIAEFKEMKGVAGVHLMAIEWEHKVPEIAERAGVLPRPTV
>D4FLW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus epidermidis M23864:W2(grey)|TrEMBL
MSHLLNQLKSNVLVADGAIGTIFYSEGLDTCPEAYNLTHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKSFGLEHKVKEIHQAAVQIAKRAANEDTIILGTVGGFRGVRQEDISLSTI
QYHTELQIDTLIDEGVDALLFETYYDLDELTRIVTATRQKYDIPIIAQLTASNTNYLVDG
TEINAALKYVVECGANVVGLNCHHGPHHMQRSFSHIELPKHAYLSCYPNASLLDIENSEF
KYSDNAQYFGDIAQELINEGVRLIGGCCGTTPEHIRYIKSAVKHLKPVKDKKVIPINKAS
SQKQTRVLKQNLTSKVKNGPTVIVELDTPKHLDTDTFFDNVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQRYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGINTDGDALKKHTNFNIAGAFDPNVRKLDGAIKR
LEKKVASGMSYFITQPVYSKEKIIQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSDDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>A0A671FG30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhinolophus ferrumequinum|TrEMBL
MLQAGPGGAIPLESDPVTLNVCWPHLYQPLQSLAGVPSFHLPSAAAAAPQPSLWSGGFVP
AHLSLCGSPSSSLKLLLCHNSAHSRHTRWGSFLCFSSAGSVSEPAEMDHPKPKVLPAGHH
CPSLGMWALEAGSVRFSVPPSISRNSVMVNEPGGHGGPNPCLEGSSIGRESSKVRSRCST
RGLKPERHERLREKMRRRMESGDKWFSLEFFPPRLAEGAADLISGFDQMRAGGPLFIDVT
WHPAGDPGSDKETSSMTIAGIAVNYCGLETVLHMTCCCQSQEKITCHLHKAKRLGLKNIL
ALRGDPVGDQWKEEEGGFCYALDLVKHIRSEFGDYFDIGVAGYPKGHPDAGSFESDLKFL
KEKVSAGADFIITQLFFEADTFCHFVKACSEIGITCPILPGIFLIQNYHSLQQLVKLSKL
EVPQQIKDKIEPIKDNDAAICNYGIDQAVSLCQTLLASGLVPGLHFYTLNRTMAAIQVLK
RLGMWTEDPRGNSSSPAFGELKDYYLFYLKSTSPKEEELLKMWGEELNSEESVFEVFMHY
LSGEPNRNGCKVTCLPWNDKPLATDPSLMKEKLLWMNRRGVLTINSQPNINGQPSSHPVL
GWGPSGGYVFQKAYLEFFTSPKTVKALLQVLKKYEFRVNYHIVDVKGENITNAPELQPNA
VTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIKQWGKLYAEASPSQEIIRYIHDNYFL
VNLVDNDFPLDNCLWQVIEDTFELLDRPPQTDRDMEAT
>A0A424JTZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaera sp. TMED24|TrEMBL
MSRIDQMFSERGPTASFEFFPPKDGEAWDALFAGISAFEQLQPSFVSVTYGAGGSTRART
HDLVVRLRSETSLLPMPHLTGRGHTKAEIESILERFAESGVDNILALRGDPPKDGDLGPG
DFPHAIDLVRFIQSFNESGGHPNGGFAIGIAGYPEGHHETPNLLTEMDHFRAKVDAGADF
AISQLFFDNRRFLDWRDRCSMAGIQIPLVAGLMPITSAGGMRRMAELAAGTLIPARLLRG
VLDREADPEMVEAFGVLWATEQSRDLLDHGVAGLHYYTLNRSRAARRVYETLGIRDSRSF
LSGS
>D1PME0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Subdoligranulum variabile DSM 15176|TrEMBL
MKIVEQFKAKRCVFSIECFPPKQTTQMEKLRGTLFAMKDLQPDFISVTFGAGGSAGGVST
VEVADLIQNELGIPALAHLICMGNDKTSAAKILDELEQVGVHDVLALRGDRTPNRPESPD
FAHACDLTAFIKSYKPGFSVHGACYPEGHPEAENLRQDVENLCTKQAAGAEHLVTQLFFD
NMHFYRFLNLARRAGITLPVSAGVMPIVKRSQIERTVALSSASLPSDFTRMISRWQDDPA
ALYEAGIDYAVRQLRDLIEGGADGVHLYAMNDAAVAKKVYDGIRDLL
>A0A2S3QQ99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovorax sp. DA5|TrEMBL
MKVIEHIDKATSPLFSFEIVPPPRGKNISAVTDIVKELLPFNPSWIDVTAHSAGAYYNEK
NDGSVERKIYKKRPGTVGICGVIQNRFKIDTVTHLLTQGFTKEETEDALIELNYLGIHNV
LALRGDALNYNKKYDLSRQRNFYAKDLVEQIDNVKKGIYLDDISNSLPLDFSVGVAGYPE
KHFEAPNLATDIKYLKEKVDAGADYIVTQMFFDNTKYFEFVDKCREAGITCPIVPGIKVI
KSMGQLSNVPRHFYVDFPDEFVNEATENSEHIKEIGIKWARKQTEELLNANVPSVHFYVM
NDSANVSEVLKGIY
>A0A0A2CQ79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus sp. MIT 0701|TrEMBL
MSEGHRDLSSALQRSIDAGAVTITAEVMPPRGADPAHSLSMAQGLKGYVHAINVTDGSRA
VMRMSSLALCRLLLDEGLEPILQLACRDRNRIALQSDLLGAHALGIRNLLCLTGDPVRVG
DQPEARPVHDYESVKLLHQVAAFNRAEDPVSGLLPDGATALFAGAAADPNCQSLSGLRRR
LERKKEAGARFLQTQMVMKPAVLEHFCNEVANPLGLPVLAGVFLLKSARNASFINRVVPG
ACIPESLVVRLEEASDPMAEGIAIAAEQVRSYLSLTQGVHLMAVKAEERIPEILDQAGIS
LVPV
>A0A5M9ZEA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium callitrichos|TrEMBL
MHKPMFSLEVFPPKRDAPVGTIYDTLDGLQGLDPDFISVTYGHGTHADRTATARIANTIR
NEYRIPTVAHLTALYSDEAKIDEALEMFEHAGVFAVLALRGDYIDGEEPVGVFEHASDLV
RYIRARKPDLKVFGACYPEGHIQSESIDEDIEHLKEKVDAGATHLISQLFYDNEDFYRFL
DKARAAGIDVPIEAGIMPINGAKSLRSMAAKNRTRIPKDVESLLERWGSDVPTLREAGIN
YASAQITDLVAHGIDGVHLYTMNRPATTRRIWRNVRPLFETAE
>A0A382W9Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKTFRHAIRNSDFAVSAEIYLRPETDAASLQAQADTLKNSVDGILLTDNQYGQLHLSTTA
AAAILLDQGVDPIVQLTSRNRNRIALVSDLLGAATIGVTSLMLVAGERAPEQFQPRPKPV
LDVNAVDLIRIANTLNADENLTVKPDFLIGGVVTPVMPKPDWKAKQLREKVDAGAHYL
>A0A383EIM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MNEIKTVVERFASGKPLFSVEFFPPKDDAAGERMLRAAQALQGYEPDFVSITYGAGGGTR
ATTLKYARMLKEQCGFDVMPHLTCVGHKEAELMDILRDFESAGFRNVMALRGDPPKGETR
FQAVAGGFSHADELVSLIRRNFPSFGVGVAGYPEKHPESPDIGDDVQRLAHKVSCGADFV
TTQLFFDNEFYFDFVNRCRQAGIEVPILPGLLPVLSL
>A0A382F9A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MNNFKNSIQNGEFVITSEIFLTPESNIQDIESQVKALGDDIAGILVTDNQSGQLHMSPVV
VGSILLNANTDPIVQLSCRNRNRISLLSDILGCLTLGVSSFSLIRGDKVPDEYQPRPKAI
MDINARELMSMAQNLKNDETISPPRNFIIGGVLTPHTPKDGWQAKNLREKVNSGAQFFFT
HTCLDMDLLSAFMKKIRQTKILEKCYIIAGIALLESIENTEWLRKNRPNVIIPNQIINRL
KEAKDQEAEGIKICSEQINIAKKIPGISGVHIIGHQKLENIPLAIRASRNLDE
>A0A7V9K5V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MTFSATTPAAAHDQPLSAVFAAGRRCFSFEFMPPRDDTGERQLWTTIRQLEPLGPTFVSV
TYGAGGSTRDRTIRITDRIAAETTLRPVAHLTCVGHHVDELRSIIGQYADAGVRDILALR
GDPPGDPGGAWQPHPGGLDRAVQLVALVKSLGDFGVGVAAFPEKHPEAADLDADARFLVD
KARVGADYAVTQLFFRAEDYLRLVDRVRALGCELPILPGIMPITNLKQVQRFATLSGSQV
PPETVARLSPYADDPAAVRAAGVELATQMCDRLLAEGAPGLHYYTLNRSTATREIHAGLA
VHA
>A0A382HI90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
KDFMSKTVDKGLTEKAFFLPGVGTLASVKTARWIKNNVPGVHIPDSIFKRLEGAEDQKKE
GQKICTELMQQVKEIEGVSGVHIMAYKQEECVAQMVKDSGVLGDRKPWAPKDEY
>A0A382BTC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MTGTDDEIHQPGRSVAPGYSSTGRLEQILRAGHFAVTAELSPPDSADPAEVYRRAALFAG
HVDAINATDGSGANCHMSSVGVCSLLTRSGYSTVMQISCRDRNRIAIQGDVLGAAAMGVS
NILCLTGDGVQAGDQPDAKGVFDFDCMSLLKTVCCMRDESRFLSNRKLSSPPKVFVGAAA
NPYAPPLDYRPYRLKKKIEAGAQFVQTQYCFDVQRFREFMTRVRDLGLHEHCFILAGVGP
LVSARAADWIRKNVPGVCIPDNVISRLQGARDQRQEGIAICIELMQQIREIEGVRGLHIM
AYRQERSVGEIVQGSGVLDGRRPFDPHSVHPS
>A0A381W233|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MSKTDKDNQEYVYHPGDPLPELEGHVSCGRFERVLRSGKFAVTTELSPPDSTDREEVYKQ
ASLFDDYVDAINATDGSGANCHMSSVVVCALLNYIGYSPIYQISCRDRNRIAIQGDLLGA
AALGICNVLALTGDDVVSGDHPEAKRVFDLDSVSLLTTIKKMRDESAFLSGRAISKPPKV
FAGSTINPFVPPVKSKVLQLEKKIAAGAGFIQTQYCFDLPMLREFMLEVVDRGLTENAFF
LPGVGTLASARTARWMQNNVPGVYIPDEIIKRLEGVDDQKKEGQLICTELMQQVKEIDGV
SGVHVMAYKQEQYVAQMVKNSGVLDGRKPWSPKDNY
>A0A2D3WFK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuricurvum kujiense|TrEMBL
MFETFIDKLRNSTYITLETTPSRSAQFAPTIEKIAALGLDKLVDGFSTTDNPLAKLKYNA
LFAAMKLQDRFGLPTLATMSMRDRNRIALQSDLLGANESNVRAILALTGDSAHYSDQPHA
KGVFEGNSKLLLDIITTLNSGTDMAEQKLLAPVQEIYPFAVIDAYAKSAATLQKKMTKKV
AHGAIAIISQPVYDLENARKLLDMMEEANRENNANCVLVLGYFPITKLRTARFLDENVPG
IYVPHTWVEALEAASLISPEEEYRVGFELSKNLFEELKALHPKIHIMTANQFELAKAILS
>A0A382BC41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKISDKLEDFKAQGKTYFSFEFFPPKTDFGLDNLYSRIDRMASLQPAYIDITWGAGGSTA
DRTLEMSKTIQKYFGLEVMMHLTCTNMSVSSINKVLMDAQENGLSNILALRGDPPEGTGE
WEKHEQGFKYGIDLVRYIRKEFGNDFFLGVGGYPDSHQEQSDIDLDISYLKEKVDAGSDI
VVTQLFYDVDKFLVFRDKCATIGIHVPIIPGIMPIHNYARFIKFTQFCKISIPNSITKTI
ESIKNDDSSVINYGIDQATAMCEKLIAEGVPGLHFYTLNLEHSVSKILELLGLTSTQGSL
RELPWRQSAAGDRKTIEDVRPIYWSNRPVSYLTRTETWDDFPNGRWGDITSPTFGELNQY
HAIRAGSKSDKVKTRRKKLWGEPKSIRDITKVFVSFCEGKINSLPWCEIPLAIESKQISK
ELTKLNELGFFTINSQPKVNGAPSEDPDVGWGSPGGRVYQKAYLEFFTSKDKLDKLLETL
DSLDNISYQAINISGDLISNLPENSINAVTWGVFSGQEIMQPTIVDTRSFLIWKDEAFGL
WISDWANIYDGESESYKLLNEVYETYYLVNIVDNNFVDGDMLKHILGS
>A0A2I8DD17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp. AONIH1|TrEMBL
MSESTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAASPSADLAHFVAKVRAGANAAITQYFFNADAYF
DFVDRAQAKGVNVPIVPGIMPITNHSQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGVHFYTLNHAEAPMAIWRELSR
>A0A381RVA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MVNLSFEFFPPKTEESEKKLWSSIKHLAPLNPKFVSVTYGSGGSTRNRTHKCVEKIINET
NLKPAAHLTCVSSSKMEVDQVIENYHEIGVKHIVALRGDMPNMGTFEPHPEGYSDSVELV
KTLHNFGVSEITVATYPEKHPESKSIDDDIEFLKRKINAGANRAITQFVFDAEILFRFRD
KIEAAGINIPIIPGIMPTTNFKNVKNMAQKCGATIPNWLEKKYEGLDDDLKARREVAKEV
GLDFCKKLISNDYINLHFYTLNQADLTYDICSSLY
>A0A838KB17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MRSAGLRAALTAARYEVLPTARIEALVVESVAAGTTLTVTASASKGLEATLACAERLTSQ
GYPVVPHLAARMIRDRGHLAEVAARMQAVGVTNVFVPAGDADPPAGDYVGSLDLLRDLTE
LGRPFAQVGITGYPESHPSISDDLTVQAMWDKRAHATYVVSNLCFDPAQLRVWLKRLRAR
GITLPVLIGLPGPVERTKLLTMATKIGVGESTRFLAKNASMFARIAAPGGFRPERFLSST
ADLFADPVDGAAGLHLFTFNQVAETEAWRGRLLARVPAR
>A0A0W7YLU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. F5|TrEMBL
MRLLERLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQKPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLDEI
LATIEEQASVLLAGNPDGLLLETYYDFEELTATLKMLRTKTKLPIIAQVSMHEPGVLQNG
MSLNNALHELEKLGADIVGVNCRLGPHHTIQAFEGVELPDKAFMSAYPNASLLDLEDGRV
VYESEAEYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVHEKYAKPEKIQI
VREAEPTKYEPLHEKVKRERSVIVELDTPRHLEIDGFLEGAKQLYDAGADVVMMADNSLA
SPRISNIAMGALLKSTNGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDVLAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNQGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEYGADYFISQPVYTKEKIVEIYEATKHLQAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSEDALARMKACGEDKERATFEGIAIAKELVEVAAQYFNGIYLITPFLRYDVTLELMKY
IEQLDEQKKGVSIHG
>A0A381QL47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKIKDILGKTRLVSFEFFPPRIAEGIPAVLETLDELKVYCPDFVSVTYGAGGSTRAFTEE
ITLAAKRSAGTEVMAHLTCVGQTKEEIHGVLERLEAEGVENIIALRGDPPRGSTEFVPVE
GGFQHATDLLQHVKSNFKFGVAAACYPEGHTESVDLDSDLKYVKMKVDSGADFLVTQLFY
DNRHYYDFLERARSGGIDVPIIPGVLPVLNSAQVRRFTALSGSEIPPDLDRLLDKYADNE
DSARDMGVEYATAQVRDLWESGVPGVHFYVLNRSYSVSRILDNLTIPGHHRQD
>A0A381UWM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
VSGTQEDTPEIRTMGKLAEALNSSSFVVTSELTPPKGTDLDELFAKADLLRDLVTAFNLT
ESHAARMAMDPVAVGHLLIDRGIEPIVQMTSRDKNRLAIQASILGAAALGVSNVVFMGGD
PPKNGDHPDAKPVFDLFASQLLEAACALNSGTDFSGNALKGTPQLTIGAVANPGASDLAG
EIDNMKRKADAGAEFFQTQAIYDVDAFDQFMNKAKPGKPVLAGIIPIKSVKMAQYMNDKI
PGVDIPQDLIDKIDAAGDDKAKVADISIEIAGSTVRALRDMTRGVHVMAIGWEDKIPAIL
DRASD
>A0A523IPR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MLFSDYFKHKDKRAIISFEIFPPKTNKGMDNLKNELSELAQLRPDFITVTYGAMGSTREK
TLDIASLIQNHFGVESACHLTCVGATKTELDILLQTIYDAGVRNIVALRGDPPEGKETFV
QSEDGYSYGNELVEHIRNFEVRTGNKHHFGIAVAGYPEKHVEAPEIGADLANLKRKVDAG
ADVIITQLFFNNDFYFDFVKRVRDIGISVPIVPGIMPILSAKQIKRITTMCGTTIPEELK
GKLDAAIDNDDKARDIGIAQCIRQSKDLLMRGVPGIHFYVLNKSRHMIRIMDALSENLDN
HKITANTP
>A0A1Q7JQF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium 13_1_40CM_4_68_19|TrEMBL
MRITDMLRFAAERGEPVFSFEFFPPRNDAGVAALFETLRALRPLAPSFVSVTWGAGGSSR
GRTLEMVTRIKRETEIEAMAHLTCVGASRKELEEQLAVICDAGITNVLALRGDPPRGQRE
FIVHPEGLAHATDLVQLAREVADKRGVSLCIGGACYPEGHPETRDLAKDLRHCKQKVEAG
ADFLITQLFFDNRRYFEFLGRARAAGIDVPILPGIMPITNVDQIERFTALCGAHIPAGLS
AALRARRDDPDAALQLGVAYAALQCAYLLRGGAPGAHFYTLNRSTATRAILAALRAQEPW
RDA
>A0A369KUV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirobacillus cienkowskii|TrEMBL
MSNKKPIAELTHCKNSFLECLSTGENILLSGSTGTLLYEKGIFINKCFEEVNISQPELVY
QIHCEFINAGAKIIITNTWGANATKLKAFGLEEKSHEINSEGAKIARKAANNQCWVAGSI
GPLGVRIEPWGPTSLNEAKTIFKNQASALVAGGADLFILEGFPDLSEIHQAILGIQEACA
LPIIAMMSVNEDGHSLYGTEPEWFIRKLDEWGADVVGIDGGNGPAPMLELIKKIISVTLK
PIILYPNAGLPRMVDGRLIYMASPEYMGEFARQALLKGVRLLGGSSGTSPAHTKIMAGAL
RQSKAFKHTEHKITMNHSAQPVHVHTSKVPRALQSQWAKKIVDGEFVITMELLPPKGLEI
DKILERAKICKNNNIDGINIPDGPRASARMSSLATACLIEQKVGIETILHYACRDRNLLG
IQSDLLGAAALGIKNILCITGDPPKMGPYPNATAVFDIDAIGLVNMVTRLNSGFDLGGSS
IGVPTSMSVGVGANPVSPNLETEKSRFRYKVEAGAEWAITQPVFDSESLFKFLEFSSQFQ
IPIIAGIWPLKSLRNAEFMANEVPGVYVPKTILKRMEKYKSADDQMQEGIQIAKELIAKI
KSSVQGLQISAPLGMVDFALKLLD
>A0A2T2U773|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QS_8_64_10|TrEMBL
MHVTELLEQSVGPPISYEIIPPKRGGSIDEVMSAVEAVMEYDPPFIDVTSHSAQAYYEEQ
PDGTWKRYIKRKRPGTIGLCAAIQSRFDVEAIPHLLCDGFTREETEDALIELNYLGIKNV
MALKGDGGAQKPVRDSRSRNEHSTDLVRQIEDMNQGTYLEEMKDAAPTNFCVGVAGYPEK
HVKAPNLTWDILRLKRKIDAGADYIVTQMFFDNERYFEFVERCRDVGIEVPIIPGLKVLS
KKRHLTFLPSYFHCDIPEALAAEVEAADDDHVADIGVEWAIQQCEELIEAGAPSIHFYIM
QNASVIQRVVEPLRAMA
>E6K3L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella buccae ATCC 33574|TrEMBL
MNVSELLHKSKGERHFSFEVLPPLKGNGTEALFNTIDKLKDFGPQYINITTHHSEFVYQE
MDNGLLKRLSIRRRPGTVAIAAALQNRYRIPVIPHVICSGVSAEDIEYELLDLQFLGISN
LLLLRGDKAKEDRSFVPAKGGHTHTTDLIRQVVRFNEGFFNDGTPIKHPGRHFDFGVACY
PEKHEEAPNLEQDMLHLKEKQELGAQYAVTQLFYDNEKFFRFVDQARAMGITLPIIPGIK
PLAKLSQLTMVPKTFHCDIPQELAAEALKCKTDEDAKALGVEWTVAQVKDLQSRGVNNVH
FYTVSAVDSVKEAVKKLF
>N9RX39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 542|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLRIVHQELQLLNPDFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKTQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCEHLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A1V2BF74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella terrigena|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVMLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A1F5AG07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium RBG_19FT_COMBO_35_14|TrEMBL
MDLREKLTANNFVVTVELDPPKTLNLDKILREVNCDNFRKAVDAVNVTDCPLAKLRMSPI
ALSHIIQEKIGLEAIFHITCRDRNLLGLQAELLGASALGVRNILALTGDPPEVGDYIMAT
GVYDVDSIGLVKMVNRLNNGHEFGEHELKDKTDFFIGVAVNPTAQDLTKEIKRFEEKVSA
GANFIQTQPIYDIGLLERFLKLTAHINIPKIIGIMPLKSYKMVEYLNNNLPGIFVPSGVK
ERMRGMDVEEGIKISREHISEIRKFKEAAGIHIFPLRDMDLVCRLFD
>A0A0R2PF70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium BACL15 MAG-120619-bin91|TrEMBL
MVSRTSYSFEFFPPKDVEGEDRLWAAIEGLKAIAPDFVSVTYGAGGSTRDRSIRIAREIT
QRTGISTVAHLTCVGSTRQELLTILQSYKDAGITSILALRGDPTGGPSAPWTATENGLNH
ADELVQMAAEFGGFTIGVAAFPDGHPASNGDFDKDVDVLIRKEQLGATFATTQFFFEADR
YTQLVNKLRARGSKLTIIPGILPVTNVKLLHRMAELGGTPIPRNIADAFAQIENDPQAVR
ALGVEIATSLCKELLAAGASGLHFYTMNSSTATQEIYRKLNDAQ
>A0A350DLA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp|TrEMBL
MTKPTFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRGRTLDIVQALCA
RGDTDIAPHMSCIGDDKSQIAELLDLYKSLGITRLVALRGDLPSGQVSMGELPFALDLVK
FIREYSGDHFRIEVAAYPEMHPQARSFEFDVDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTVAQPLVAGIMPITNSSNLVRFADSCGADIPRYVRKRLADFGDDRTAIREF
GFDVVYRLCERLISEGVPAMHFYSMNKVEPNKRLVEALGLIA
>Q8CJA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mus musculus|TrEMBL
MVNEARGSGSPNPRSEGSSSGSESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFS
LEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRG
>A0A7W3ISC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microlunatus kandeliicorticis|TrEMBL
MSAATDLRPGQPSASASMPASLPAGATRGKPDPTITDLLATAGRPLFSFELFPPRDEEQE
RQLWLTVRRLEALAPDFVSITYGANGSTRGRTIRATQQVAENTTLRTMGHLTCAGQSRDE
LRRAVGAYADVGVRHVLAIRGDMPGGPTEPWVRHPEGLANATELVELVTSLGDFCVGVAA
FPDVHPQARDADLDARILVEKARAGAGFAITQLFFTAQRYFELVDRVRSLGCDIPIIPGI
QPVTQLRQIRRFAELSGADLPPAVVARLQGAGDEPGAVSRVGVEIAAELSEELLAGGAPG
LHLYTLNRSRATREIYARLHPGSRRP
>A0A7X3XAV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0662_bin_26|TrEMBL
MTPRTLQHTLAQGQFAVTVELNPPKGTDVSELLETAKSLSGRVHGINVPDNAAAVLRASP
VAVARLLYEQGHDPVLQLTCRDRNRLGLQSDLLGAHVLGIRNVLCLTGDSPGAGDHKDAK
PVFDLNTVQLMHAVQELNEGRDLAGNALEGRTAFFIGGAAAPGGEPTELLHKKFEAKVNA
GAEFFQTQPVFSAKVIQPFMEAVRPYSRKVLAGVLVLRSIKMAEYVNAHVPGIDVPDEIL
QELRNAGDAHVSEAGIEIAVRTIRAVRPFCNGVHLMAGRLAHRLPEIIRKAELN
>A0A0K9GC52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. FJAT-27916|TrEMBL
MRLLERLKGEILVGDGASGTLLYSFGIDTCYEELNLTNPERIAELHKEYIEAGADLIQTN
TFGANYHKLKRYGLEGEVERINREGVRLAKEAAAGRVYVLGTIGGLRSVRKSELSLTEIG
TYFKEQLDALLLEEPDGLILETYYDLEELLHVLEIARKQTNLPIVANISLHEVGLLQNGM
QVKDAFDLIKGKGADIIGLNCRMGPYHMIRSFEEVPLREDAFYSAYPNASLPDFTDGRYV
YSTDADYFVSAAKQLVEQGVRLIGGCCGTTPAYVRAIKKGILGLVPLTEKKEVISRKSHV
YTYDFRQPDKETILGKVKKGPAILVELDPPKTLGVEEFMKGSRYLHEMGADAITLADNSL
ASPRISNVAIASLLKAELKKNPLVHLTCRDHNLIGLQSHLMGMHTIGLNEVLIVTGDPSK
IGDFPGATSVYDLSSIDLISLVKQFNAGISYSGKSLGGQTNFEVAAAFNPNVKYVDKAVV
RMEKKIQAGADYFLTQPVFSVEKIREVYEATRHIKAPIFIGIMPLTSYRNASFLHNEVPG
ITLPEPVLRAMEKAGTDAEASMRESLAISKELLDAAAEYFNGHYIITPFMRYELSGELVA
YASTKKSVISGDVFEQ
>A0A1D8D6Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobaculum limnaeum|TrEMBL
MLVKEILDARTEPVFSLEFFPPKKQEDWDKLFETISNLSPLDPSYVSVTYGAGGSTRERT
HNLVTRIQQETGLTVVSHLTCIGAEKSEIEGVLQLYREHGITNVLALRGDKPADIPTLEE
AIKDFPHAIDLVRFIKANFPEMGIGVAGFPEGHPETPNRMKELEFLKEKVDAGADYIVTQ
LFFDNRDYFDYVERCELAGITVPIIPGIMPVMTKKGMIRMGELALGSRIPSKLLRKVLEA
SDDKEVAEIGIEWATKQVQELLDHKVKGIHFYTLNLSEATLKIFRNLKRG
>A0A654CC93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. 8AM|TrEMBL
MTFSVNQLEEARRALEAPLYADVGGDVEVSFEFSPPKTDKAEENLWQSIETLCPLSPRFL
SVTYGAGGSTRDRTHATVARIARETKVPAAAHLTCVEATRDEIDAVAQEYWAAGVRHIVA
LRGDPPAGAADYAPHPGGYENAAALVEGLRRLHPFEISVAAYPEMHPNSADLAADLDNLK
RKLDAGANRAITQFFFEAETFFRYRDAAAAAGIRAEIVPGIMPIGSFAGVTRMATMCNTD
VPGWLVRLFEGLDDHPAARQLVAATVAAELCRKLYAGGVKQLHFYTMNKAELSFAICHLL
GVRSRPAQERAAA
>A0A2T6B0V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allosediminivita pacifica|TrEMBL
MRRPEISLEFFPPKNIEGTFRLWDTVQVLAPLNPRFVSVTYGAGGTTRDLTRDVVATLHK
HSGLRTAAHLTCVEATKEETREIVRGFADAGVKDIVALRGDPPKGADGFTPHPEGYANSV
ELIESLASEGDFNIRVGAYPDVHPEAADGAADIDWLKRKLDAGATEALTQFFFEADTFFR
FRDACVKAGIDKPIVPGILPIENWKGARRFAESCGTKIPAWVIDAFEKAERDGRSDLLAT
AICTELCSELIEGGVDKLHFYTLNRPELTRDVCHALGVTPDVRLENVA
>A0A2N3GX60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium HGW-Actinobacteria-1|TrEMBL
MRRHVEWQVRGPSRPRLHARAHPASPHRAGERRHEGAARQGLLEEAQAGLRQSSRVEEGR
CQVSRLSDALERGEFVVTGEIAPPLGTDLAAMRHSIETIGPYCHAINITDNQGASLHLSS
LAASRAALEMGFEPIFQQTCRDRNRLALQSDLLAAWTLGLENVLIVTGDDPRSGDHPEAK
GVFDLDSTQLLEVAAQMNAGTDMIGRPLKGGTDFYLGAAMFPEAEPWDIQLLRAARKVEA
GARFFQTQAIFDITKLERAVDALRPMGAKIIAGVLVLRSARAVDFINERLAGLMVPEEIG
ARIKSADNAAAEAIKLATEQVRAAREVADGVHIMTLGLDDAVPEILAGAGLS
>C1DUH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurihydrogenibium azorense (strain Az-Fu1 / DSM 15241 / OCM 825)|TrEMBL
MKIVDKLKKEKVSISFEFFPPKTKELEDSLFKTIEELKPINPTFVSVTYGAGGSTREKTR
DIVKKIHEETNLTVMAHLTCVGHSKQEIKQILEDYKNIGIENILALRGDIPLSFDKKDIP
LDGCKHAFELVSLIKDNFGDYFCIAVASYPEGHPESPNLERDIYYFKQKVEAGADFSITQ
MFFDNSYFYDFLDRCTKAGVNIPIIPGIMPITNFNQIRKFASLCGATIPEDVVKLFEKYA
DNPEETKKIGIEFATKQCEDLLKNGVKGLHFYTLNKSDATIKIYNNIKALL
>A0A3R9MGH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mangrovimonas spongiae|TrEMBL
MKVTEHIKNAKGKTLFSFEIIPPQKGSNIQELYNNIDPLMEFKPPFIDVTTSREQHVYIE
KDGLLDRKITRMRPGTVGICASLKYKYNVDTVPHVLCGGFSKEETEYLLVDCHYLGIENV
MALRGDAMSHQKYFEPSKGGHLYANELVKQIQNLNKGKYLHDVIEADDKADFCIGVAGYP
EKHLEAPSLQTDLKRLKHKVDCGADYVVTQMFFDNKKYFEFVKAAKQAGIHVPIIPGIKP
ISIKKHLQLLPQVFKIDLPEELINAVENCKDNKAVRQVGVEWCVQQSKELQDAGVPVLHY
YSMGKSDNIKAIAEALF
>A0A1H3FTF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter sp. DSM 44400|TrEMBL
MQRGDGVRAHVLSAVVTGTVRELLDQQRPTWSFEFFPPKDAAAEAQLWTALRQLERLRPS
FVSVTYGAGGSTREGTVAVTERIAAETTMLPLAHLTAVDHSVAELRHVVSRLAAAGVRNL
LALRGDPPGADPQAEWVAHPQGLRYAAELVELIKSIGDFSVGVAAFPERHPRSVDFETDT
EMFVAKCRAGADFAITQMFFQVEDYLRLRDRVSGRGCDVPVIAGVMPVTSARQIARIVQL
SGQAFPTELADRFTALSGDRPEDKRAVRDLGVEVATGMCRELLAEGVPGIHFITMNRSTA
TREVYANLVPARVPVP
>A0A3A3H3B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus thiaminolyticus|TrEMBL
MKDLRQVLQGEIIVGDGAMGTYLYQMGYPVGISYESLNISEPERIRDIHREYVSAGARLL
ETNTFTANREKLSKHGMEKQVKAINRAAARLAREAAAGQAYVVGALGSIRAGKRENIATD
QVKRDYTEQLSALLEEGVDGIMFETFYDMEEMKLAVQIVRALDDRIPIICQFAVEESHRT
KDGLRLLDAFRLLREEGADVVGLNCRMGPNGLMRAMEEVTGRLALPMSAFPNAGLPDYVD
GRYNFVATADYMAESAVRFAELGARIIGGCCGTTPEHIQAIAQALADAETPILPTLAEEE
AQAQAVPPLEIGERGAAPASGKGKAASGPSLVDTVRERHTVIVELDPPRDLDIAKFMLGA
QALKDAGADALTLADNSLAVTRMSNMALGYLALDKIGIRPLIHIACRDRNLIGTQSHMMG
LDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEIIRMIKQLNAGLAFSGKVLKQRANF
VVGAAFNPNVKHLNKAIERLERKIEAGADYIMTQPVYDASLIERIAEGTKHLNVPVFLGI
MPLASGRNAEYLHNEVPGIHLSDEVRERMKGLEGESGRREGVAIAKELLDVAMKHFNGIY
FMTPFMFYEMTAELTEHVWQKAERLTAPLYRHT
>A0A3D2RH26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MIYEIEKWIKEKLFDCQSCGQCVLSHTAMVCPMNCPKGLRNGPCGGTLEGKCEVLPEKTC
VWTEIDQRKKPSFETLHLSPQKELYNTASYVNLVNGKDRKTRLPQDVVDLGDIPASSSLS
EKMYGEEFVVTLEIASPRTEDGLRRVERIMRRVADHVDAVNTTTNAGGVPSLHSTETAKV
VRAHGVESVIQFCGRDHDEPDLLREIESALDMGYRNFLLLTGDWLPNVEPGVSQKTWFPM
DSLQMIHAVNRRLRDYQQRLGVVPFIGCASNPFSTPIEVSLRRLHNKRHAGARFSQTQAV
TNVDTFARWYEGLREGREAEARLTIPSIPLVGSQRMFEVLCRLPGVYVDPSLHAVMDNKD
HQQNALEWAFGIAEGVTENGAAGVHVMNFGMPPELIDAFLVEIRERGRAARSRYEKASA
>A0A737BRP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. indica serovar 45:a:e,n,x|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6L6VIL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium vitis|TrEMBL
MAHTSSNRDQARPFKLSFEFFPPKSEEMEAQLWATVDELTGWEPEFVSVTYGAGGTTKAP
TLAAVRRLLAETPLATASHLTCVGATREEIAQVVEDFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGFENAAALVKGLKELGDFEISVSAYPEKHPESADLAMDLDMLKRKVDNGATRALT
QFFFDNDIFERYLDKVRAAGINIPIVPGIMPILNLTQLKRFAGMCGTSVPAMLDQRFEGL
DDKPVERASVAAALAAEQIADLQGRGIDEFHIYTMNRAPLVNATLERLGLQRSDTVAASR
AGVIA
>A0A7S7ZHF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. CCBAU 53338|TrEMBL
MSGAMTETTTPGHTDGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVT
YGAGGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRG
DPAGGIGTPYSSHPEGYQSSADLVAGIKRRHADIEVSVSAYPEKHPEARDFDADIDTLKA
KVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTV
PDWFAAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLG
IRAKSAQKAA
>A0A8E2V3V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. CB-A|TrEMBL
MTSPAVSFEVFPPKSVDASFRLWDTAQALAPLAPRFFSVTYGAGGSTRDLTHDSAHVLRR
TSGLPVAAHLTCVGASKAETLEVADSFAEIGVTDIVALRGDPENGAPTFTPHADGFADSV
ELIEALAKTGKFTLRVGAYPEPHPESHDQAQNVEWLKRKFDAGADEAITQFFFETETFLR
FRDACAAAGITKTITPGIMPVTNWKSARNFATRCGASVPAALDEAYAAAIRDDRHDLLST
ALCTEMCSELVSEGVENLHFYTLNRPELTRAVCRALGVTAQTSLSDVA
>A0A7V6SRR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierellia bacterium|TrEMBL
MKITDIMKERMSLSFEVFPPKMEQPLEPLLETIEDLYKFKPDFISCTYGAGGTNAGRNVE
ICKYIEEGKKSIPVTHYTCIGNQKDNIKDDMRNYLDLGIDHILAMRGDFPKGWTETRGDF
DYANELVKFIRENFPEFQIAIAANPEKHIQSPSFDSDIAHLRNKQDMGGDLIMTQLCYDV
DHYEWWVDRIRKAGIHLPIDVGVMPVLSKDPTIRMAVSNGSAVPRELAEVIGKYGDNPED
FKKAGKEYTVNLIHKFMTAGIDGLHIYTLNKSQDVTDILHAAGFPSY
>A0A7K1PIQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium vitis|TrEMBL
MAHTSSKRDQARPFKLSFEFFPPKSEEMEAQLWATVDELTGWAPEFVSVTYGAGGTTKAP
TLAAVRRLLAETPLATASHLTCVGATREEIAQVVEDFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGFENAAALVKGLKELGDFEISVSAYPEKHPESADLAMDLDMLKRKVDNGATRALT
QFFFDNELFERYLEKVRAAGISIPIVPGIMPILNLTQLKRFAGMCGTSVPAMLDQRFEGL
DDKPTERASVAAALAAEQIADLQARGIDEFHIYTMNRAPLVNATLERLGLQRSDTKAADR
AGVVA
>A0A7X4I9X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. BIOML-A1|TrEMBL
MRLKEYIQTKRIIADGAFGTYYMSLYGDGSKPEKGLAISNLPELANITAPERVIGIHTEY
IEAGAQLIRTNTFASNTKSLLSDTEAVKENIRAAVTCAKAAAEKAEHEIYIAGDIGPIPA
EGVPHSDNLTKEYIMIGETFIEQGIDILLFETFPELETILPAIAYLKETHDCTILVHFSV
NQFGYSNTGLSAKRLIADAEACRYIDGTGLNCGVGPGHMKKLIRNISADDATFLSVFPNS
GYPKYLNNRLTFTDNAEYFAEKISEIAESGICIFGGCCGTTPDYIRKIAAGISPDYPVGS
RETVAEVTVSSEKPAYGFMERRVKDPSHKLVAVELVPPLNADDEKLLDAAHILKNAEVDV
VTFPDSPSGRTRADSVLMAEKIRLETGLCVMPHICCRDKNAIAIRSTILGASLNHITNFL
LLTGDPVPVLFRQTTKSVFNFDSVGMMKIVQEMNSDTFSEHPVTYGGAINHNRMNTKAET
ERIRRKMAAGATFFMTQPIFSAEQAEIIRQMKKETGATILVGLMPLVSRKNAVFMKNEMT
GIEIPDSVIDRYREDMSREEGENCGIRLAREFMAMTDDFADGYYFSFPFNRVHMLKKILG
>A0A1C5IZ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora inositola|TrEMBL
MALGLPSVLPNPQPAIGELIRAGQPTFSFEFFPPKTEQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVPHPQGVHYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCQAGAEFAITQMFFDADDYLRLRDRVSAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALADRFERVADDPEAVRRLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWQHLR
SNARV
>A0A1I3MIT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jannaschia pohangensis|TrEMBL
MPTVSFEFFPPKSLEGSFRLWDCVNTLAPLAPEWVSVTYGAGGTTRELTREAVATLGKQF
GLRVAGHLTCVDASREETLEVARGFKAAGVTDIVALRGDPPKGAKGFVPHPDGFADSVEL
IAALAQEDFTVRVGCYPDVHPEAASAEADIAWLKRKIDAGASEAISQFFFDADSFLRFRD
RCVKAGIDAPIVPGLLPIEDWTKASKFARSCGAYIPDDLAAAFEVALRDDRADLLAIAQA
AELADRLVEEGCEHLHFYTLNRPELTRDVCSALGLVPEPALSRVA
>A0A1R4EFP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter pasteurii|TrEMBL
MNKPQFSFEFFPTKTDEGITKLYQTFDTLNEMAPSYFSVTYGAGGTTRERTLGIVAALKS
RANTPIAPHISCIGDDKSQIAELLDFYKSIGIDRMVALRGDLPSGQVGMGELPFAVDLVR
FIREHSGDHFQIEVAAYPEMHPQAKSFDSDIQNLVNKFEAGANSAITQFFYNAESYLYLR
DALEKRGVDTDKHRLVAGIMPITNSTNLIRFADSCGADIPRFIRKQLADYGDDRKAIREF
GFEVVHRLCEVLISEGVPALHFYTMNRVEPNKRLVESLGLTSANTQA
>A0A292SQD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Gastranaerophilales bacterium HUM_21|TrEMBL
MNLKEIYTTKKQEPVISYEVFPPKDDIDATKLEKLFDELKKLLVFNPSLISVTYGAGGSN
QNESVEIIKRIKQELNVSPMPHFTCVSTSTENIKNYLKTL
>A0A5D2FEE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium darwinii|TrEMBL
MKVIDKIQSLSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
NIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DVLVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>F9PHE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. oral taxon 175 str. F0384|TrEMBL
MRSGPTAEHQFSVCGTAAGLGNSRGLIRSTIQSGRETWFHDAAATRYAGASARIDGDDVH
DNEPTGPTAAASSRGKALSSAETGTARRLPTVSLELFPPRPGKAASATWGRIDRLLATGP
DFVSVTYRPTFVTDPAGGVTGGGRQGSAHEPEAGRCEAPRVRAVQEQTNPSECVLAHVLD
SSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRAEDVAGELRHADD
LVRVIREVEADFFGDGRRHVTIAVAAYPATNDHIEAIEILAAKQAAGADMAITQVFYDAA
DYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPAGLRSSLGSASGATLVE
RGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDAVDR
GYLQATPGRGPSFLRRGSARATVSSHHPVQPLTTITKENA
>A0A1H1SZT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces flavus|TrEMBL
MTGSAPVGDAVRPRPPISFELFPPRTDAAALALGRTIDRLAEVDPAFISVTFGAGGSSRD
RSLTVLRYMLEHTDVEPMAHLTCVGSSHAEANRLVREFLDAGITSFLALRGDPPEGADPE
AGIGDLRSAAELVQLIHRVQEEREPYGQAGIPGIPGATRIRERPRPERVAVAAFPTGHPR
SRGFGQDIDVLLAKEVAGANLAITQLFWHADDYLGFVERARAGGVTIPILPGIMPVTTPA
RLARLEQLTGVPAPSELAIPLEIEPDADALFELGVDFAAALAAEVLADAPGLHLYTFNRH
EAVLAVLDRLGLRTIPAHAGTERNTRTR
>D1BQ68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella parvula (strain ATCC 10790 / DSM 2008 / CCUG 5123 / JCM 12972 / NCTC 11810 / Te3)|TrEMBL
MTLREKHQQGQFTITVELDPPKSSSAEKTFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDAPTNFYIGATGNPGAPDLEIERQKLAAKIQNGA
HFVQTQPIYDLEQAKRYIDKMAEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
MEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A6I9SWY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sesamum indicum|TrEMBL
MKVIEKIREATAANDNRVVFSFEFFPPKTEDGVDNLFERMERMVAHNPTFCDITWGAGGS
TADLTLEIANRMQNMVCVETMMHLTCTNMPIEKIDHALVTIKSNGIQNVLALRGDPPHGQ
DKFVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEGHPDVIQDGGVAPPEAYENDLAY
LKRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNFKGFLRMTGFCK
TKIPPEIMAALEAIKDNEEAVRAYGIHLGTEMCKKIMASGIRTLHLYTLNMEKSALAILM
NLGLIEESKISRPLPWRRPANVFRVKENVRPIFWANRPKSYISRTVGWDQYPHGRWGDSR
NASYGALGDYQFLRPRSRDKKLHEEWAVPLKNVEDIYENFMKFCLGKLRTSPWTELDGLQ
PETKIISEQLGNINLKGFLTINSQPAVNGAKSDSPSVGWGGPGGYVYQKAYLEFFCSPEK
LNALVDKCKIFPSLTYMAVNKEGIWKSNVSNTDVNAVTWGVFPANEIIQPTVVDPQSFMV
WKDEAFEIWSRGWAKLYPEDDPSRKLIDEVQGKYYLVSLVDNDYVHGDLFAVFKDI
>A0A2G4JKJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacterium sp|TrEMBL
MKPFLAALDDRVLVCDGAMGTMLYAKGVFINRCFESLNQTQPDLVVAVHGDYLKAGADVI
ETNTFGANRMKLRGFGLGDQVRDINLAGATLARRAVEKSGQPAYVAGAIGPLGVRIEPWG
KTGIDEAEAMFREQAQALVDGQVDLFILETFRDLNEIGAAIAAVRSVCDLPIVAQMTTEE
DGASLDGAPPEQFAPDLIARGASIVGVNCSVGPAPMLETIERISEVTNGWLSAQPNAGKP
RDIEGRNLYLCSPEYMASYARRFIASGVRLVGGCCGTTPEHIRQMALAAKSLAPGLARHA
GTAEVRTPVASQPNARPSLPREAKSSMGRKLANGSFVRAIELVPPRGHSASAALADASRL
VQRGVDVVTIPDGPRSGARMSALSLAVLVQQHAAVEVLLQYSCRDRNLLGIQSDLLGAHA
MGVRNLLGITGDVRKLGDIPDATAVFDVDSIGLTNVITRLNHGLDISGQSIGEPTSFHTG
VMVNPSRDLDQELRRLEFKIEAGAEFAVTRPVFDVPTFERFLERVSPLGVPIIVGIWPFE
SALNAEFMANEVPGVTVPEAIVERMRRTTSAEAAAAEGVAVARELVAAIKGMAAGVQIST
PSGRLDAALDVLDVV
>A0A6I4KP64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas xionganensis|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMTVARQLASYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVGVSTAPHLSCVGDSKAELRELLSTYQSNGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGDHFHIEVAAYPEMHPQARSFEDDIANFVRKAKAGADSAITQYFFNADCYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTDSIQAYG
EQVITEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A7W0LMS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MKIDRILEEQRPCFSFEFFPPKTPEGEQNLENALQELRHDEPQFVSVTYGALGSTRERTI
DITKHIKQDLGLEAMAHFTCVGATREELLATLAEIQEAGIENVLALRGDPEEGQDVWTQT
EGGLRYSTELAELISAEFPFSVGAACFPEVHPEAESPESDLRFTKAKIDSGASFLITQLF
FDNDLYFHFVSRAREAGIDVPIIPGIMPVTNFKQIKRITGLCDATIPPEFERELAARQDD
AEALTELGVAYATLQCADLLARGAPGIHFYTLNKSPATRAILAALRAARPWDRALAPV
>A0A662G6G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoprotei archaeon|TrEMBL
MRFYENYPSELLLDDGFKIKPRIKHREYFTKLLSRTYERITWIAEIPPKAGITKKLHILR
EMTEDALSIPDNPFGRTHIEPTAFAAYLGNLTKSEIVVHLTCRDLNRLALKSRILGLDLI
GVKHVLALTGDHISPYEGNRLMGVFDLDSMRLIYMIRLLSDYGLDERGRRITDKVTLHVG
GGLNPYLPLEIELSRILRKLNSGSEFFISQIIFDESY
>A0A6M1R708|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. KC13|TrEMBL
MDLQQRISDRAGEILLFAVTPPRVTTDPERVQQIAEVTLERIRPLDVDGLILYDIDDESD
RNPEERPFPFVRTLDPAQFLERNLAGLDVPAVVYRATGKYDESTLRDWVKTQDPAKALSV
FVGASSGEKRVATSLRRAQEIRQETNPDLLLGAVAIPERHTAKGDEHLRLIAKQEAGCSY
FVSQVVYDVNAAKNLVSDYRYECESRGLQPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENELRHATDTLDASLEQAEATAIELMSFCRQLGVPFGINIESVSIRKVEIEASVRLAERL
RGKLDR
>A0A1H2SQ27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicyclobacillus hesperidum|TrEMBL
MPSGGWETWAKVPRELAVAGGRYVIFDGAMATYLHQCGVPIRVCAEELNLSKPRLVEQIH
RAYVEAGATVVQTNTFAANRLDLARHGLDAQTVAINEQAVLTARAAVADRASVYGTMGPA
AGGTRYGALLTADERSRLSQVYEEQAFALIEAGVDGIVLETFPDLEELLLALRVVRVMAP
QLPIVANLSPEEVGVTRDGVLLTKAFATLREAGASVVGLNCRLGPYGILRSFEQIVFDDG
PYAAVPNGGILHRSESEGLAYTGDVDDFARVMSDIARLGVRWLGGCCGTTPEHIHKLVLA
LQAQDRGETWAEPPQKPSSIHVVADNRRDEMEGMGAETPLGPSIVDTLKERTAVIVELDP
PKHLSAARFLAGATALSEAGADMITMADNSLGSVRISNMALASVLKQRGIEPLVHVTCRD
RNLIGQQSHLMGLHVLGVRNILLITGDPSRYGDLPGATSVYDVSSMDLTKMVRKLNDGVG
FSGKPLQRPAQFVIGTAFNPHVHNFAKAVDRLRRKVEAGADFVMTQPVYDPVLMEQIAEA
TRDLGVPILIGIMPLTSARNAEFIHHQVPGISIPADILSRMRETAPEEAQEVGMEIAKSL
VDRALTYYRGIYLVTPFLKFEITVRLTAYIRERTATAVASAARRE
>A0A1N6L7S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia phenazinium|TrEMBL
MNPLELSFEFFPPKTADGVEKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLQAAPHLSCIGSSKESLRAILNEYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDREAIRAFGLDV
VTDLCGRLVDARVPGLHFYTLNNAAATKSICDRLGGSLAA
>A0A1Z5SGD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium IBVUCB1|TrEMBL
MKVTDHLSQAKGPIVSLEILPPTKGKGIHSIFNHLDPLMEFKPAFVNVTYHRAEQVLKKR
TDGSFEQIEIRKRPGTVSICAALMNRYKIEAIPHLICGGFTKEETENALIDLNFLGVKNV
LALRGDAAANEKFFTANPKGHRFAEDLVKQVVELNNGKYLEEDIIDGVKTDFCIGVAGYP
EKHFESPNADTDMYYLKRKVDLGADYIVTQMFFNNAHYYNFLKRCADSGITVPVVPGLKP
LTGQKQLTTIPSIFNVEVPVDLVNEMMKSKSADAGDKIGEEWLYNQCKDLLANNAPVLHF
YTLGKPMVVYNVLKRLF
>A0A2E8P6F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivirga sp|TrEMBL
MTTEILASAVRGFSIESVPQDADRIDDFRDHVPTGTRVFIAWPPKATPESIVKSARKLHE
QEMVPVPHIAARRVPSQEFLRAFVGDLVAQAHVREVLVIGGDPATPEGPYTDTGSLLRSG
VLNEFGIEKVGVAAHPEGHPVMSGAVSREVLADNLAAARDHGMSVEAVSQFVLDPQAIDS
WHAEVYSSLAQGAPLLIGIPGLVSGTRLLKIANACGIGESIGLLRKNGLRMAKTVIGNSS
TQTLVEGLAPLANRATDVGGFHFYTFGNFEQTAAWACEAASTPAAAAG
>J9VMK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)|TrEMBL
MPHLTSLIAAHNGPFHNYEFFPPLTDPGFVNLLDRIRRLTSPPFQAPLAVSVTWGAGGST
AEKSLELAQQVVGMGVEVILHLTCTNMPKDKVDFALRRCKDLGISNILALRGDPPREEEY
AINPTSTPDFFKHADDLVRYIRQTHGDYFCIGVAGYPNPHPDSESEEEDFKWFKAKCDAG
ADFIVTQLFYDVDVFLEWVKTCRAKGINQPIIPGIMPIQNYASFRRLVNLTKCPVPDSIT
SDLQPISSDDATVKRYGAELATKMVNQIIGSGLVPGVHFCTLNLEKSVRKILDNLGWSAA
SKASENEGVVKNKLIEDDSRAVNGIPINGKADTAQSPAKNLSISPSEANQLAQLGLTSTT
LPPAPKTGLGAQGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKEWGVP
ISTSDLSALFTAYLHSDPKHLTTPFCDLPLSPESHMILPHLLALNSAKVQHWTVGSQPAV
DAARSEDEIVGWGPRGGYVFQKAFVEFFVTENEVNRLKEKVKKEGKGLITMYAANRKGDF
KSNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWTEWSLLYPRNTPSRKL
LEGIANEWWLVSLIHHDYKDQDALWRFLLEDLQ
>A0A536WU71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTTSLPVPVSFEFFPPNTPVGSEKLKTVVSELASAGPEFFSVTYGAGGSTRDKTLATVSD
IAALGHEAAPHLSCVGSTKEGISEILATYRAQKIRRLVALRGDLPSGTATAGEFRFASEL
IAFIRETQGRDWFIEVAAYPEYHPQQRYARRDLQHFAAKVKAGADSAITQFFFNPD
>A0A536YEZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTGSADRIFSFEFFPPATPEGVAKLRATREQLERLGPKFFSVTFGAGGSTRDRTLAAVLE
IQGAGQRAAPHISCIGSTRESIRATLAAYREHGIGHLVALRGDLPSGTADVGEFRYANEL
VEFIRVATGDWFHVEVAAYPEYHPQSASPREDLASFKRKIDAGADSAITQYFFNADSYYH
FVDEAVAAGIEAPIVPGIMPILSFSKLARFSDACGAEIPRWIRRKLESFGDDTASIRAFG
LDVVTDLCDDLLAHGAPGLHFYTLNQASLTTIIWQRLGLS
>A0A098Y7T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter caceresii|TrEMBL
MTGTVRELLQTERPTWSFEFFPPRDAAAETQLWTALRQLEQLRPSFVSVTYGAGGSTREG
TVSVTERIATDTTMLPMAHLTAVDHSVTELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WVAHPQGLRYAAELVELIKGIGDFSVGVAAFPERHPRSADFDSDTDMFVAKCRAGADFAI
TQMFFRVEDYLRLRDRVTARGCDVPVIAGVMPVTNARQISRIVQLSGQAFPVELAERFAA
LDGDRPEDKRAVRALGVEVATQMCRQLLDEGVPGIHFITMNRSTATREVYTNLAGADLVS
>U2R6S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia sp. oral taxon 879 str. F0557|TrEMBL
MHKLIKNNLISNLGGLMKIKDMFEQKEHLISFEIFPPNKNFSEEKLKNVTAELVEYKPDF
ISVTYGAGGKTKGGTIEMASYIKNNLKTEVLAHLTCVGSKKSEINDYLQEAKNHNVKNIL
ALRGDVPVGETEEIYNKGDYKYASELIRDLRKNREFHDFSIGGAFYPETHYENNDLVDLF
HLKNKVEAGTDFLTSQMFFDNNIFIKFKEQAEKLDIKVPLVAGIMPVTNAKQIKRIIELS
KCSVPKKLDKLLEKYGDNLESMKKAGIMYASEQIIELLAYGIKGIHIYTMNKPEIAREIM
KNIEFAR
>A0A536SYK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MVTERRAASDLQARLRSGEFVITAEITPPVSIDPAEFLRRAMPLKGLATAVNVTDGAGAK
VHLSSLATAHFLVSSGIEPIFQMTCRDRNRLALQGDILGAAALGIRNILILGGDDPKAGD
QPEAKAVYDLDSRTLLAMAHRMRTDNTLPTGTKIAGPPLRLVLGAADVPADPAPGWRPTG
LKAKIDAGADFVQTQFCMDTGVVRRYTRRLAEAGIRTPILIGVAPIPSAKSARWMRDKLF
GTIIPDAFVERLERAADPKLEGRKICIEVLRELVDIPGVAGAHVMAPMNFAEIPAVIAES
GVAGRRVNHAVH
>A0A351UMW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
IPGLMPVTGYKQLSNFTQMMKVSVPAELRAGLERWADDKESLFKFSVEHASAQAAELLAR
GAPGLHLYTLNRSRAAIAILKNVKGKAG
>A0A1H7RQF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parapedobacter koreensis|TrEMBL
MKVTEHIKKAKGKTLYSFEILPPVKGQSIQSIFDAIDPLMEFSPPFIDVTYLREDYIYKQ
HPTGLLEKVAYRKRPSTVATCAAIINKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARKSDSSFIPTPGGHAYASDLLQHVVNMNSGRYLHEDMENSEKTDFCIGVAGY
PEKHFEAPNLDTDFKYLKMKVDLGADFIVTQMFFDNTKYKAFVDKCRENGIHIPIIPGLK
PLTSSKQLVSLPKIFHLDIPVELSEAVQACKSEQEVREVGVEWMIQQCKELKEMGVPVLH
FYTMGNPKPTKRIIKAVF
>A0A254SV09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWB1|TrEMBL
MKIVDILKQDKMSLSFEVFPPKKETSFENVKAATESIAALGPAFMSVTYGAGGGVSHFTL
DIAKNLKEKFNIPMLAHLTCVSSSKDTVHQRIEDMKAAGIKNVMALRGDLTPELIEKGRD
NCDYHYAVELIRELKASNADFCIGAACYPEKHPESVNQAEDIKHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFAG
>A0A6I5WD75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. WMMC415|TrEMBL
MALGLPSVLPNPQPAIGELIRDHQPTFSFEFMPPKTEQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGAGVRNVLAVR
GDPPGDPTGEWVPHPEGVRYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVATDTEYFVR
KCRAGAEFAITQMFFDAEDYLRLRDRVAAAGCDTPILPGVMPVTQFSTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQASEMCGRLLDEGVPGIHFITFNRSTATREIWQNLQ
AGARV
>A0A674NI82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Takifugu rubripes|TrEMBL
QVSKPRRSSNSSGESSKESSRCSTPVLDADRSDRLRDKMRRRIESGDHWFSLEFFPPRTA
SGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTC
CNQTKDKITGYLGKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAVDLVKHIRSEFDDYF
DICVAGYPTGHPEAESYQQDLRHLKEKVDAGADFVITQLFFRAETFLKFLDDCRTIGITC
PILPGIFPIQGYQSLRQLVKLSKLEVPEEITSILEPIKDNDAAIRNYGIQLAVEMCRVLL
DSGKVPGLHFYTLNREVATMEVLRQLGLWTEDPRRPLPWAVSAHPKRKVEDVRPIFWASR
PKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEELLSEES
VFEVFTFYITAQSNRCGQKVLCLPWNDEPLAQETNLLKDELEKVNRRGVLTINSQPNING
KPSTDPIVGWGPAGGYVYQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTN
APDMQPNAVTWGIFAGREIVQPTVVDPVSFMSWKDEAFALWIEQWAKLYEDESPSRMIIQ
YIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDSPAAPPCEDATP
>A0A1H0U2L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium gasigenes|TrEMBL
MNIRELFEEKNLVFSFEIFPPKVSSSVETIYNTLEELKDLTPDYISVTYGAGGSLTENRT
CELSSLVKSKYGIESLAHLTCINSTKEEIDFLLRDLKNAGIENILALRGDMTSHKLSKGE
FNYASELVNHIKRRGDFNIVGACYPEGHIDCKDLDRDILNLKLKEEAGASHFISQLFFDN
NYFYDFLEKKEKYNIKSPIQAGIMPVINKKQVERITSLCGTNIPKKFLKIMDRYEHNKEA
LRDAGIAYATEQMVDLISSGVDGIHLYTMNNPYVAKRINGSISSIINSVNNGNAI
>A0A0E3QP53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina barkeri str. Wiesmoor|TrEMBL
MLFNFREKLNSSKFLVTAEVSPPKGTKFSVSLEDVRQLKGIADAINVTDNQCSIMHMSSL
AFSKLLLDAGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICVMTGDFPSCGDHPGSKP
VYDLDSVQLLQLVRKLDSGINFTGNRLDGGTSFCAGAVSGIDPEKPLQLIKLEKKVRCGA
DFIQTQAVYDVGMFEEFMEAISHIEVPVIAGLIPLKSLGMAEFMNRNISGVHVPEEIMLR
IKDAPDPVEEGLSIASETIKEITKLSRGVHIMPVGSHKNTARLLSMAGISGK
>A0A7K0H044|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides distasonis|TrEMBL
MKVIDLIRNSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIHYLKEKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A3R9EM76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus sp|TrEMBL
MSLKTNATYYPAMPTAFKEKLLSDEFVITSEISPPKGVDVSSAFEEAELVRDYVDAFNVT
DNQRAVMRMSPLAMGHLLKERGLDVIMQFTCRDRNRLALQSDLLGAYAMGMENVCIMSGD
YPTKGDNPGAKPVYDLDSV
>A0A1B8ZJJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium arthrosphaerae|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFRPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINNLGRGKYLHNEEQVCDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELISEVENAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A1G7ZGV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium changbaicum|TrEMBL
MKVSEIVKEKRIISIEIIPPKRGENVENIYKSLDKLMKYDISFINITRHPVAVDYIEHED
RIIKVQKVKRPGTIGLTAALMNRYKIDVVPHLVCVGMNKFEMEDTLIDLDIMGVDNVFVI
RGETDQNNGSYTKGDYRYAVDLVQQIRDLNSGKYLYTKAKPTNFCIGVAGYPEKHYESPN
AETDLKFLKQKVDAGADYIITQMVFDAEVYRSFVERCRMVGIDVPIIPGIKPVVSKSSVF
NIPKKFFVNIPQKLVEAIDNAKTKEEEFRIGISFTVELVEKLIEYGAPGIHVFTMGRGEE
SCEVIKFAQSIIK
>A0A4U5URW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collichthys lucidus|TrEMBL
MGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQTKEKITGYL
GKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAIDLVKHIRSEFDDYFDICVAGYPTGHP
EAESYEEDLRHLKEKVDAGADFVITQLFFRAESFLQFVDDCRAIGITCPILPGIFPIQGY
QSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRNYGIQQAVEMCRVLLGSGNVPGLHFYT
LNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWD
EFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLQMWGEELKNEESVFEVFTCYITAQ
PNCHGHKLNDFFALCVYHGRPQAKTLLCQVVGQVMEGGQASHHPFPPALPVEEEVGGTLE
DQILLVGVAYSQVMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQPNINGKSSTDPI
VGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGHNLTNAPDMQPN
AVTWGIFPGREIVQPTVADPVSFMYWKVR
>A0A562LNH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter ruishenii|TrEMBL
MTDPAPGPRMTLPISFEFYPPKTDEQRAQLDKTAAKLKAHSPDYVSVTFGAGGSTLSHTP
EAIQYLRGQHGYDAAPHITCMGGSREEIRGLLKLYKALGARRLVTLRGDLPSGMVSPGDL
RYASELVEFIRNETGDHFHIEVAAYPETHPQARDAHTDLKAFATKVKAGANGAITQYFYN
ADAYFRFVDDARKAGIDVPIVPGIMPISNFSQIRRFSELCGAEIPRWVAQRMQAYADDVD
SVREFGAEVVAQLCRRLIDGGAPGLHFYTLNLSKPTLNVLARIGVV
>A0A4P7IEE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides seonyuensis|TrEMBL
MTQDPGRSMRDLIEGGDRSFSFEFFPPKDEAGEEQLWRAITELEPYRPTFVSVTYGAGGS
SRDTTVRIVERIARETSMLPVAHLTCVGHTTDELAAILRDLSDAGVRHVMALRGDPPGGP
GSPWTPTEGGLDHADALVAFIKRTIDARVGVAAFPEGHVDAPSLEADAQVLKAKQDAGAE
FAVTEMVLRASDYAALVERARAIGVDIPIIPGIMPILSLRSMQRMAELSRRDLPAEVVER
LTPHADDAAALRAEGIAIATELCEQLLGDGAPGLHFYTLNFSRATREIFTGLQITV
>A0A1Z4LBZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc linckia NIES-25|TrEMBL
MHHTHSPTAFRRAVQAGEFLVTAEVAPPKGGDPSHMIKMAATLKGRVHAVNITDGSRAVL
RMSSLVASVILLQNGVEPICQIACRDRNRIGLQADLMGAHALGIQNILALTGDPVKVGDH
PDCKAVFDLEAVRLLQVIRKLNQGVDCNDKSLTDGALDLFPGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFECLEKFMDTIAAGYKKPILAGIFLLKSAKNAQFINKCVPGVN
IPQHIIDRLAKAKDPLEEGMKIAAEQVRIARQLCQGVHMMAVKREDLIAPILDLAGVTTV
NQLVSR
>A0A5C8UWI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. WL19|TrEMBL
MPTASHHRASRDGYRPIQVSIEFFPPKTDEMEKVLWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMIKETSLKPAAHLTCVDATREEIDEVVQSYWDAGVRHIVALRGDPQDGVG
TAYRPHPGGYARTSDLVAGIKRIGDFKVSVSAYPEKHPEAATLDADIDALKAKVDAGADQ
AITQFFFENDVYLRYVDKVRAAGIEIPIIPGILPVQNFKQSANFARRTGASVPYWLAARF
EGLDNDVDTRRLIAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKV
AAAKAA
>A0A1B7JUQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia heimbachae ATCC 35613|TrEMBL
MSFFHVNQREALNQSLAELDGQINVSFEFFPPRSEEMEQTLWKSIDRLKNLKPNFVSVTY
GANSGERNRTHSIIKDIKDKTGLIAAPHLTCIDASRDELKEIARDYWNNGIRHIVALRGD
LPDNSRKPDMYATDLVELLKAEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLDRFAKMTNVRIPSWMRKMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A511QHA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sagamiensis NBRC 104589|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKHLQPKFVSVTY
GANSGERDRTHSIIKDIKAATGLVAAPHLTCIDATREELNAIADDYWFNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVVLEV
>A0A257UWF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiphilium sp. 37-64-53|TrEMBL
MSHEPPRAALQRWLSGPRIAPLPGGIQAVPDISFEFFPPKTEALEAQLWACIRRLEPLAP
QFVSVTYGAGGSTQERTHATVLRLVRETSLIPAAHLTCVGATRGAVDDVARRYWDAGVRH
IVALRGDVPGGAPYQTHPDGYAFASDLVAGLKRVADFDISVAAYPETHPQAASPAADLDN
LKRKLDAGANRAITQVFFDTSHYLDFLDRALAAGITAPIIPGIMPVSNFAQAKRIGEMGG
TSVPAWMGEMFDGLDDDAETRKMVAAAVAAEQVRILQANGIDEFHFYTLNRADLTYAIAR
ILGVKGK
>S3CIB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiostoma piceae (strain UAMH 11346)|TrEMBL
MHIRDMIIEAERDGKPSFSFEYFPPKTAQGVQNLYERMERMHLFGPKFIDITWGAGGHVA
DLTAEMVSQAQNYFGLETCMHLTCTDMGEAAVNDALRRAYKAGCTNILALRGDPPRDQET
WEATDGNFCYAKDLVAHISKTYGDHFDIGVAGYPEGSDDNKDEDLLLDHLKQKVDAGASF
IVTQMFYDVENFTRWLRRVRERGITVPVLPGIMPIATYASFLRRVNHMGCKIPKGWLDAL
EPVKNNDDAVREIGKTLVAQLCRDILADGDVKHLHFYTMNLALATRMVLDELDWLPTADR
PRAPPALPWKQSLGLGRRDEAVRPIFWRNRGKSYVSRTADWDEFPNGRWGDSRSPAFGDL
GSAYGVGLPGTNAQNRGKWGEPRSIADVASLFVRYLKGELQSLPWSESPLTGEANSIQQD
LINLNQNGLLTINSQPAVDSAPSSDPVHGWGPANGYVYQKAYVELLVPPALYSELISRVA
ANPHLTYHSVTWKGKLETNAPADGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLG
SDWSRCFDVGSPSRGLIRQMMEEWHLVTIVNNDFHKPRTIFEVLSGLSLPDIDKEVEAAP
EEAAAAPSAPTNVTAGKLSAAPVNGVAEAQKTPIPA
>A0A6G2M2G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4923|TrEMBL
MALGTPSTRSDSAQSIRDLLSEGDRSYSFEFMPPRTPEAEAGLWKAIRKLESLAPTFVSV
TYGAGGSTRGRTINVTGRIAQETTLTPVAHLTAVDHSVAELRNILGHYADQGVRNILALR
GDPPGDPLGTWTRHPEGVCHAAELVSLIKESGNFCVGVAAFPEMHPRSSDSASDLRHFID
KCRAGADYAITQMFFDVDAYLRFRDLVSAAGCDTPIIPEIMPVTTLRSLRRIPDLSTAAF
PDELAARMLAAESDPAAVRAIGIEHATEMCHRLIAEDAPGLHFMTMNFSTVTTEIYRNLG
LAP
>A0A2V6NNJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MNLFDELQDRVVCGDGAMGTLLLDQGLPMESCLEEVCISDPDRVRAIHRDYIAAGARVIE
TNTFGANAARLSRFGFENRVGEFNRAAAKVAKETAAGKDVCVGGSVGPLGISALEAEERG
IDRAHCFHEQIEALLDGGVDLIFLETFMDDFEMQIALEAKNSLSDCTTICSFACEPEGRL
ASGVPIVDAFRKLRGLGAQITGVNCMNGPHATVQLLQRIPLDGLLATYPNAGYPKYTEGR
FIYHAAPDYFAQAAREMVAEGARLIGGCCGTNPRTIAAISKAIAEMKPVKSKTVRVTAIA
LAPAKKVAAVVEESLLDKIAAGKRVIICELDPPKTLALEKYFRGAQELVRSGCDAITLAD
NSLAILRVSNLAVGAMLKERFGITPLLHLSCRDRNVLGLQSELLGMAALGMRHVLPLTGD
PARVGDHPGASSVYDVNSIELISIIGKLNEGFSHAGKSLKARTQFVIGCTFNPNAKNLDS
QVNRLERKVAAGAQFAMTQPVFCVRLVEETKRRTAHLNIPIFIGIWPLMSARQAEFLHHE
VPGIIVPDEVRKRMADSPLENAGAIGMEIARDIVSAVGSEFPGVYLITPFLHFDSTCELA
RFAREM
>A0A0L8RA23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces eubayanus|TrEMBL
MSIRELYHERTSPFISLEFFPPKTELGTSNLMERMHRMTALDPLFITVTWGAGGTTAEKT
LALASLAQQALNIPVCMHLTCTNTDKTIIDDALNRCYSAGIKNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGNEQDPLKDMVYLKEKVN
AGADFVITQLFYDVEKFLSFELLFREQISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
SILNRFPPEIHSDDNAVKSIGVDIIIEIIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SSALSHIINESSEEEVEDETGGEIESIENVPIEDADGDIVLDDSNDDAAENRKRRRHSSL
DSSKMIFNRAIVTEKGLRYNNESGSMPSKKALISISRGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKNRALELWGTPEAVGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWET
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPYSSSVVTWGVFPNSQVKQTTIIEEESFKA
WRDEAFSIWSEWGKLFPRNTPANILLRQVHRDYCLVSIVHHDFKETDELWEMLLDQV
>A0A829LEZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 907889|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1T1GRQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4945|TrEMBL
MSLFSQYLLQRQFCISLEYLTTQKPHLVPKTFAGFPVCMTLADRVQSDTDIAPLEALHDY
PQSIEKILHYSGKGRDISDFQTFLKDAQQHGVENLLLLSGDKLKQHQDGANDPSLRSRYL
ESVNQVMAAKDFGGFYLGVAFNPFKYAEAEKDAQYFKLNKKIQAGADYVITQLGFDMDVL
SSYQRYMQQYYPRVPVLACVMPLTFARARFMAKQKVAGIVLSADVLNFLQQEQQTDAIQA
EQNVYARCALQILMCQQLGYAGVHLSACHKAEEQEKLQKAILQFAKLTYEQCLAKWKMLW
RSSVEVNFQPTGANNHKAPIEQVLKYKSMHVMHELFFSSKLAKGAGSYIFSAKLWQKPKA
DAALLQTEFISKHGIVGCESCGQCRLGETLYICPETCPKGLANGPCGGSNLDRCEFEDRE
CIHSVKARLAKAVGQEKMLKQELIPTVAIETRHSSSWKNWFVPPTSSPTEQ
>A0A2H0JXK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium CG12_big_fil_rev_8_21_14_0_65_60_17|TrEMBL
MKVVDLLMGADAPQISYEIVPPKRGSSVSDIFEIVDGLIPFDPPFIDVTSHSAQVYYEEQ
PDGTWRRRIRRKRPGTLGLCAAIKGRYGVETVPHLLCEGFTREESEDALIELNYLGIHNV
MALRGDEGRYRKPVTGSRTRNEYAVDLVRQISDMNKGFYQEEMAGAVRTDFCIGVAGYPE
KHFEAPNMAWDVQNLKKKINAGADYVVSQMFFDNRVFLDYLQVCQQAGIDVPIVPGLKIL
TRKRQLQSLPSTFHLSVPEELAAEVMEADDRHVPEIGIRWALKQCEELLAANVPYLHFYI
IQTPEYVQPLIERLRKMA
>A0A077HMR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium ureicelerivorans|TrEMBL
MFEDTPSTRLSASAPLDREGAPLIRRPRPKRQRTALSFEIIPPRPTDDSAKIDELIAGLA
EYNPDYVSVTSSRRSEWLEGTAAVISRIEETTDLRTIAHLACTAGTRDEIAEWVRVLIDA
GVRGFLALRGDLPETGLPADHLQYATDLLNLIQDVQEEEAFRLAGGKLALSVACYPKGHA
ESRNLDHDLDVLLTKQRLGADFAITQLFFEAQDFLEFVEVARLAGVRIPLIPGIMPMTSL
KRVKRMGELSGLEVPEGVEKQLRDADDEYEAGMQLTADLAREILDAGTGGLHVYTHNNLA
VTRDFLDRIGIDRGQQ
>A0A2V5THU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRANSPTFSFEFFPPKTPEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
GLVERIQHTTKLDPIPHLTCVCHNEEEIQAILLRYAKSAIGNILALGGDRPAGIAYDKSR
ESFQHAIDLVKFIRRFNESRAHPERRGFGIGVAGFPEGHPATPNRLVEMDYFKAKVDAGA
DYVVTQLFFDNRDFLDFRERCTLNQIHVPIIAGIMPITSITGCKRMAELAGGTRFPATLL
RALQHCQNNPEMVRRVGIQYALEQSHDLLDNDVAGIHFYTLNRSDATRIIFDSLGIPRHP
NTPVSTV
>R7L4Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coraliomargarita sp. CAG:312|TrEMBL
MKLSRNIGDKFANKETVFSVEFFPPKTEEGARQILRTANRLRGVSPDYVSITYGAGGSTR
ERTVEYGELLREIFDFEVMPHLTCFGNSKSEILDMLKRFDSSGFCNVMALRGDPKKGETV
FVPHPDGFKHASELVGFIREKYPHFGIGCAGYPEKHPEAKTLDEDIGYLKKKIDAGADFI
VTQLFFDNSHFFRFLDKCRSAGINKPIIAGLLPALSLKQVSNFKAMCSSDIPQALLERLA
NAPDGDGAKVGLEWARMQIEELKSAKVDGIHLYILNRADSALELARLIKSK
>A0A2V5QM59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIIDIMRGNSPTFSFEFFPPKTPEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIEAILLRYAKSAIGNILALGGDSPAGIAYDKSR
DSFQHAIDLVKFIRRFNESGAHPDHRGFGIGVAGFPEGHPATPNRLVEMNHFKAKVDAGA
EYIVTQLFFDNRDFLDFRERCALNEIQIPIIAGIMPITSISGFKRIAELAGGARFPAKLL
RALQRWQNDPETVKRVGVQYALEQCRDLLDNDVAGIHFYTLNRSDATRVIFDSLAFPRHR
NAQASSA
>A0A3F2U504|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. YM1C-6-2|TrEMBL
MSEQRPIHPDENPEGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKVFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPVMQIACRDKNRIAIQGDVLG
GAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQ
LFLGAAINPFAPPYDFRPIHLGKKIAAGAQFVQSQYCFDVPMFRTFMQKASDLGFTEKVF
ILVGVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEIPG
VSGVHVMAYRQEEYVAEIVDESGVLKGRRPWKREARADDALVAQRLDHLLNDNITETQVD
MVKSAH
>A0A2V6I5X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHIADIMREDSPTFSFEFFPPKTPAAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
HLVERIQHTTKLDPIPHVTCVCHNENEIEDILVRYAKSAIGNILALGGDRPHDIPYDKSR
DSFQHAIDLVKFIRRFNESGAHPDPRGFGVGVAGFPEGHPATPNRLIEMDHFKAKVDAGA
DYIVTQLFFDNRDFFDFRERCALADIHVPIIAGIMPVTSMSGFRRIAELAGGARFPAKLL
RALRRCENDPESVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRVIFDSLGIPRRR
NAQAPTV
>A0A2V5Q2C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIIRANSPTFSFEFFPPKTPEAAEILYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHRTKLDPIPHLTCVCHNEEEIEAILLRYAKSAIGNILALGGDRPAGIAYDKSR
DSFQHAIDLVKFIRRFNESGAHPDHRGFGIGVAGFPEGHPATPNRLVEMDYFKAKVDAGA
EYVVTQLFFDNRDFLDFRERCALHDIHIPIIAGVMPITSIGGFKRIAELAGGARFPAKLQ
RALQRCQNDPEMVRRAGIQYALEQCQDLLDNDVAGIHFYTLNRSDATRVIFDSLALPRHR
NAHASSA
>A0A2E4G224|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MDFVKKLKQGDKTLFSFEILPPLKGKSIQSIYDGIDPLLEFDPAFVNVTYHREEFIYKKR
EKGFLEKIAIKKRPGTVGICAAIKNKYNIEAVPHLICGGFNKEETENALIDLHFLGINNV
LALRGDPIKTEPHFVPEDGGNRYAVDLVEQIVRLNNGIYMDPNIENATPTNFSIGVAGYP
EKHFEAPNMDADIKRLKQKIDAGAHYIVTQLFFDNKKFFEFCERCRAEGIEAPIIPGIKP
IESLRHITFLPKFFNIDLPVELTNALYQCKTNEDVRNVGAEWAIAQSKELIEAGVPCIHY
YTMGKSKTVSKIAKSTF
>A0A2V6AGJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIIRRDSPTFSFEFFPPKTPAAAEVLYQTIRDLESYMPNFVSVTYGAGGSTRDLTH
DLVERIQHATKLDPIPHLTCVCHNEEEIEAILLRYARSAIENVLALGGDRPRDIPYDKSR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYMVTQLFFDNRDFFDFRERCALAGIHVPIIAGIMPVTSIKGFKRIAELAGGARFPARLL
RALQRCENDPEGVRRVGVHFALEQCHDLLDNTVAGIHFYTLNRSDATRVIFDSLGIPRRR
SAQAATVQSSDEVREPLAS
>A0A2V5SVP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDILRGDGPTFSFEFFPPKTVEAAEILYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIEAILLRYAKSAIGNVLALGGDRPAGIAYDKSR
DSFQHAIDLVKFIRQFNQSGAHPDHRGFGIGVAGFPEGHPATPNRLLEMDHFKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALVGINIPIIAGIMPITSISGFKRIAALAGGARFPAKLL
RALQRCQNDPEMVRRVGVHFALEQCHDLLDNDVAGIHFYTLNRSDATRVIFDSLGIPCRR
KAQVSTVS
>A0A0D5A2F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus str. P0902-H212|TrEMBL
MKSKLQKRLESGLSAITAEIMPPRGGNTASAISKAIKLKDLVHGFNVTDGSRAIMRMSSL
ALCKLLLEANLEPVLQLSCRDRNRIALQAELLGAHALGITNILCLTGDPVRVGDQSQAKS
VQDFNSIELIKQVTSLNKGIDPVSDLLPDGPTNLFAGAAADPNCRGFDGLRRRIELKKTA
GANFLQTQMVMDPKVLERFCREITEPMKIPVLAGVFLLKSAKNAQFINNVVPGACIPESI
ISRLESSSNPIDEGISIAADQVKSFLGIAQGVHLMAVKAEQQIPIILDRANIN
>A0A5C0DZE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dolichospermum sp. UHCC 0315A|TrEMBL
MQDTHSFSAFNNFRKAALAGEFLITAEVAPPKGGDPVQMLAMAATLKGRVHAVNITDGSR
AVMRMSSLVASVILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPQAKAVFDLEAVRLLQLIRNMNQGVDFNEKPLTDGALDLFAGAAVDPQSQSWSGLQS
RFEKKIVAGAQFFQSQLITDFEILEKFMDKIAVGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEEGMKIAAEQVQIARGLCQGVHLMAVKREDLIAPILDLAGV
EKVS
>A0A4P5YU50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MLRSQFLQALRDPVRPTVSVEFFPPKTPEAGAKMLDVARALRPAGIDFASLTYGAGGTSR
DTTLAYGAELVKLGFPLVGHLTCVGHSRAELTDVIAGYDTAGFAGILALRGDPPKGQAAF
TPHPEGFAQAEGLVRHISTVRPGRFAVGVAGFPERHPDAVDDLSDIRFLAGKVAAGADFV
TTQLFLDNDDYFRFVARARAAGVTVPILPGVMPVLSLKQARNFCGFCKARLPEGLIQELE
ACGPDEEAQRRVGVSWAVRQVRGLVARGAPGYHVYILNRSESAVELFAQLKS
>A0A397ZD18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica campestris|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRANGIQNVLALRGDPPHGHDK
FVKVEGGFGCALDLVNHVRGKYGDYFGITVAGYPEAHPDVIGENGLASDEAYQSDLEYLK
RKVDAGADLIVTQLFYDTDVFLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEVMAALEPIQDNEEAVKAYGIHLGTEMCRKILAHGTKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALTDHQFSRPRARDKKLQQEWVVPLKSVEDIQERFRELCLGNLKSSPWSELDGLQPE
TKIINEQLVKLNSKGCLTINSQPSVNAERSDSSTVGWGGPGGYVYQKAYLEFFCSKEKLD
AIVEKCKALPSITYIAVNKGDNWVSNTAQSDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFETWSRSWANLYPEAADPSRNLLEEVKNSYYLVSLVENDYINGDIFSVFADL
>V4VQH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrus clementina|TrEMBL
MKVIDKIQEKVASDKVVFSFEFFPPKTEDGVENLFERMDRMVAHNPAFCDITWGAGGSTA
DLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDK
FVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLK
KKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTVHLYTLNMEKSALAILLNL
GLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRTVGWDQYPRGRWGDSRNP
SYGALSDHQFMRPRSRDKKLHEEWAVPLKSVEDIYEKFKNYCLGKLRSSPWSELDGLQPE
TKIINEQLGKINVKGFLTINSQPAVNGERSDSSSVGWGGPGGYVYQKAYLEFFCSPEKLT
ALVDKSKVLPFITFMAVNKEGNWKANVNQTDVNAVTWGVFPAKEIIQPTVVDPASFKVWK
DEAFEIWSRSWASLYPEGDSSRKLLEEVQSSYYLVSLVDNDYINGDLFTVFADL
>N8ZHU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter gerneri DSM 14967 = CIP 107464 = MTCC 9824|TrEMBL
MSKRVPISFEFFPPKTDVGAEKLRVVHAELQKLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHTGDHFKIEVAAYPEMHPQSETFDADIQHFVEKVQAGANAAITQFFFNPDAYFYFV
DRIQKVGIDIPVTPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDAESIKAFGHE
VVIKLCERLIAGGAPSLHFYSMNQVEPNRQLVLDLGLA
>A0A8D9Z3R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus D139|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAATKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A840KB70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium defluvii|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYRNIDPLMEFKPPFIDVTTSREEYVYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTPGGHASAMDLVHQINNLGRGKYLHDEGQEYDEHNKFCIGVAG
YPEKHIEAPSMNYDLKWLKEKVDAGADYIVTQMFFDNKRFIEFVQKAREMGITIPIIPGI
KPIATKKHLKLLPQVFKIDLPEELIHDVEKAKNNEAVKEIGIEWAITQCRELLDFGVPVL
HFYSMGKSDNIKRVAGELF
>A3WRU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrobacter sp. Nb-311A|TrEMBL
MTDAFAPAHNDPGARKRPTISFEFFPPKTEEMERSLWSTITRLAPLDPSFVSVTYGAGGS
TRERTHSTIARILSETRLRPAAHLTCVGAPRGEIDEIVSRYRDIGVRHIVALRGDPPGGI
GTAYSTHPEGYRSSTDLVAGIKRRHGDIEISVSAYPEKHPESPDIDTDIDILKAKVDAGA
TRAITQVFFDNDLYLRYLDRVRARGIEIPIVPGIMPMHNFKQARTFVTRAGTTVPAWLAE
KFDGLDEDPETRKLIAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAICHLLGIRPDAA
RKAA
>A0A418MVH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora radicis|TrEMBL
MALGLPSVLPNPQPAIGELVRDCQPTFSFEFMPPKTAEGERQLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGAGVRNVLAVR
GDPPGDPTGEWVPHPEGVDYAEDLVRLVRRSGDFSVGVAAFPYRHPRSADVASDTEYFVR
KCRAGAEFAITQMFFDADEYLRLRDRVVAAGCDTPILAGVMPVIRIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQTSEMCQRLLDEGVPGIHFITFNRSTATREIWQNLR
VGAPT
>A0A1E4IRJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus sp. SCN 64-35|TrEMBL
MSGRTFSFEFFPPKTAEGAEKLRATRAQLAQLKPKFFSVTFGAGGSTRDRTLEAVRDIQA
SGSEAAPHLSCIGSTRESIREILGEYKSQGIRHLVALRGDLPSGTMDAGEFNYANELVSF
IRAETGDWFEIEVAAYPEIHPQARAWKDDLANFKRKVDAGADSAITQYFFNGDAYFRFVE
EVRALGVAIPVVPGIMPINNYLQLARFSDACGAEIPRWLRKKLESYGDDLVSIRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPSTTIWQRLGLS
>A0A2C6Y4D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas rhizosphaerae|TrEMBL
MNHLADHAASAGTPGTLQRWLTGPRVAGLPVPTELPPPALSFEFFPPRTEALEQQLWSCV
RRLEPLAPRFVSVTYGAGGTTQERTHATLSRLVRETSLTPAAHLTCVGASQGEVDDVARR
YWADGVRHIVALRGDAPAGEEGYVPHPQGYAYAADLVAGLKRVADFEISVAAYPETHPTA
SSAQHDLDNLKRKIDAGATRAITQYFFDTEVFLRFLDRCHAAGITVPIVPGILPVSNFNQ
VRKFSAMCGASVPDWMGRLFEGLDDDPETRRMVAAALAAEQVRLLQANGVDEFHFYTLNR
ADLTYAISHILGARPKAAPAA
>X6KN31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L103C105A0|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDEIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>X8KGD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. CM6|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>J9WMZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces tendae|TrEMBL
MTTLRDTLGRGTPSFSFEFFPPKTAQGERTLWEAIRRIEPLAPAFVSVTYGAGGSSRDRT
VEVTKRIATQTTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGDPNAPWR
RHPDGFTHAHELVALVKESGDFSVGVAAFPERHPRSPDWDSEIRHFVAKCRAGADYAITQ
MFFRVEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIARFAALSGAAFPEDLAHRLDAVR
DEPAEGHRIGVEHATAMAQRLLAEGAPGLHYITLNRSTATLEIHRNAANPRSTRHVLAAQ
H
>A0A1M6QKG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter intestinalis|TrEMBL
MQKFAFTHCFNKKSCYIIRMSFRKPKNIALELVPRTLDGVLAEARESLSSFPFVTSINIP
EIRRLPIKSFEPSKHLLESGLVTTPHFRLIDRSEKDLLQKIAVLVEAGLSQVLLIGGDPP
KESPDFVPSGLTTLQAVQAVKREFPQLKIYTGLDPYRSSFREELDYARAKRDAGSDGFFT
QPFFSVGMLELWLEQLPDAEIWFGIAPVYTERSQNYWERVNKVVFPPNFSFDRDFNTRLA
RQLLVTISETQQRAYLMPVANGALAYLRDIFEA
>A0A1A6A4Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kwoniella dejecticola CBS 10117|TrEMBL
MKITEKLQKAEKEGRTFWSFEFFPPRTAQGLQNLYDRIERMRNLGPEFIDITWGAGGKNA
DLTSSLVQVCQETIGIETCMHLCCTEMPKEKVEWALAQAKQHGCQNILALRGDPVAGTSK
WEPTPGGFTNAVDLVKHIHEHYPGDFCVAVAGFPQGHPETPEGEDAGKQEIQWLKEKVDA
GAEFIFTQLFYDVNIFFNWVKRVRAAGITVPIVPGIMPIQNWEKFEKWVARENIVVPQHF
YDALKPVKGDDEKVRQVGTKLVAQMCKEILANEEAGIKGLHIYTLNLEKGARMLLQELGL
EGRREQIAPLPWRPSLTPHRRTESIRPIFWANRVQSYLSRTDEWDEFPNGRWGDSRSPAY
GDLDGYPVSININANDAYNLWGHPETFADISNLFAKFCRGDLNKLPWSSQPPASETSVID
EQLAKMNELGYLTINSQPAVDGVSSDDKVHGWGPSGGYVYQKAYLEFFVSPELLSPLIRR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWANLYPPASPSRNLIESTMNTSYLVNIVANDFRDGMSIFEPFLLKQNSVGKVLEST
TQTVNGVYEGVKEGLNGLVENVKHQINGVNDASTNGNGNGVAVDGH
>A0A4R8J2U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiohalophilus thiocyanatoxydans|TrEMBL
MESQKKYSPVYSVEFFPPKSEEGAEKLRKVRKNLNKGMQPRYYSVTFGAGGSTQQGTFDT
VAEIQKSGDDAAPHLSCIGTTKDGLRELLSGYKENGIKRIVALRGDMPSGMRGPGELRYA
NELVEFIRAETGDYFELEVAAYPEIHPQAPSASDDLKNFKRKVEAGADTAITQYFFNPDA
YFRFIDECERMNVDLPIIPGIMPIINYKQLSRFSDMCGADIPRWIRKRLEDFGDDKESIK
QFGEEVITDLCHTLLEAGAPGLHFYCMNQSAPTLAIWKNLGIQN
>A0A806E3N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae (strain R2866)|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A496T865|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MGKSFREHLEQDEVLVCDGAMGTMLYSKGIYINRCFDELNLSNPAMVKDVHLDYLKSGAD
IIETNTFGANWFKLEPHGLEERLYEINFQGVKIAREAAGGKAFVAGSIGPLGRPIEPIGH
LSQEKARQAFYDQAKAQFEGGVDLFILETFKDINEIHQALLAVKDVCDLPVIAQMAFTDE
GKTAYGVSPEEVVRKLEGWGADVVGINCSTGPEGVWKAIQEMARVSDIPLSAQPNAGFPQ
LVQGRLLYLASPEYFAEYAKRFIQSGVRIVGGCCGTTPAHIRAIRTAVKALRPSRQLVEV
KVVEVEEKVLQVKKPAEKSKLGEKLGKKFVVSIEMNPPRGPDFSKVVEGARRIKVAGVDA
VNIPDGPRASARMSPLALATILESKVGIETILHYTCRDRNILG
>A0A654F1R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arabidopsis thaliana|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFDCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIGENGLASNEAYQSDLEYLK
KKIDAGADLIVTQLFYDTDIFLKFVSDCRQIGINCPIVPGIMPINNYRGFLRMTGFCKTK
IPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKMLAHGVKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALSDHQFSRPRARDKKLQQEWVVPLKSVEDIQEKFKELCLGNLKSSPWSELDGLQPE
TRIINEQLIKVNSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLD
AVVEKCKALPSITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWK
DEAFETWSRSWSNLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIFAVFADL
>A0A7J7M6C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingdonia uniflora|TrEMBL
MKVIDKIKEASTKKKVDFSFEFFPPKIEDGVDTMFEKKIEWFPILLPVTSLGVPVILQLI
SLSTFPTTKDAKHETMMHLTCTNMPVEKIDQALDTIKSYGIQNFLALRGNPPHGYDKFVK
TEGGFAYALDLVKHTREKYALTTYTMKACLLEFEFGLMKKMKSGLMRKMVIGYWVKGRDP
LDYFGITVWVIQGKKSLKQDELKDLMMLGVPKSSAIGKAIKKLTICKVPDFGMLFEMDRS
PANEVSTSGRIVESKIEMFDSEVKVGDEQFPGFPGKLVTYPPCSNAFKEFYKTKATVGGT
WGNCVEYAGRLFRGCTVATGEEYFYLLADLEEEKRDSGIDESISLKYFDESVQMGKEGKV
RRISPEDVLQFYGVKNYHASGGAYFCASTTQPRFFDLNSSGRSWNDNVIWVKGPKSQVER
KDSLLDEVAKEEVKLESVLEGLGLSRKERVGSKFKKVQKSQSTRLMAGVEDGKKKGTGGE
GRTNLLKSPRVGGSVHLESITLRKLVRTFTKKYMLKRLSASSTTGSGEVEGKEKRRRIEP
SRTSGEKVVK
>A0A2D9F364|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MPNVPTDNLHQVAAFGRAAISGTSVAAPLPDDVEVSFEFFPPATDGAEDRLWNSIQRLAP
LNPKYVSVTYGAGGSTRERTHSTVKRLLDETDLLPAAHLTCVDATTGEIDKVAQDYWDMG
VRHIVALRGDPQDTSGVYKPHPGGYAFACDLVSGLRQIGDFNISVGAYPEVHPEARSAKA
DMDNLKRKIDAGADQAITQYFFDTDVYLRFVDQARAAGIWVPIIPGIMPIHNFKKVANFS
KRCGATIPRWLIDLFDGLEDDPETHKLVAASLVAEQCRTLHAFGDKQFHFYTLNQADLTY
AICHMLGVRPKPTAGDDDRAEPDNQQSKKQKAI
>A0A7U8C5H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neptuniibacter caesariensis|TrEMBL
MHTKMKQDLKTKFSDSSRGVYLFGTTPPKDGIEDATVSSIADKLLERLAHVEFDGLIVYD
IQDESSRIDKPRPFPFMRTLDPRAYSKLLREKSEKPVITYKSVSQRDEAAFTEWLDEAWN
KYGVRDTVLVGSPSSEGEIQLSLNDAYKVIEKHPAQYQLGGVTIAERHASKRNEHERLIS
KIDQGCDFFVSQAVYDAQATIDMLSSYARKCREEGITPKRVILTFTPCGSTKTLEFMEWL
GISVPEATRFRIMDAHNPLQESIRICRNNLEQILEAVMPLDIPIGLNIESLTNRKEEIDA
SIRLFKLLKSVVDLKLAEAAL
>A0A496TIC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
AQMAFTDEGKTAYGVSPEEVVRKLEGWGADVVGINCSTGPEGVWKAIQEMARVSDIPLSA
QPNAGFPQLVQGRLLYLASPEYFAEYAKRFIQSGVRIVGGCCGTTPAHIRAIRTAVKALR
PSRQLVEVKVVEVEEKVLQVKKPAEKSKLGEKLGKKFVVSIEMNPPRGPDFSKVVEGARR
IKVAGVDAVNIPDGPRASARMSPLALATILESKVGIETILHYTCRDRNILGMQSDLLGAH
ALGLRNILIVTGDPPKLGDYPTATAVFDVDSIGLVRIANNLNNGTDLAGNPIGAATSFHI
GVGANPGAISFEEEISRLKQKIEAGAEYILTQPVFDIKLLEKLLDGIKEYKIPVLAGILP
LVSYRNAEFLHNEVPGMSIPKTVRDRMQRADSGEEAKKVGVQIAQEVLQEVKNMVQGVYL
MPPFGRYEVALQVVEVLK
>A0A8I2JUF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus agalactiae|TrEMBL
MSKFLEKLKTDILVADGAMGTLLYTYGLDTCHESYNVTHPEKVLAIHQAYIEAGADVIQT
NTYGAQRHRLKNYGLEDQVVSINQAAVNIAHQATLGKETFILGTVGGFRSQRQCDLTLDN
IVEETLEQVEALLATGQLDGLLFETYYDIEEITTVLKIVREMTDLPIITNISLHEAGVTS
NGKPIVEALSQLVMLGADVIGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASQLSLDGE
NSQYQFSQNSEYFGKSAELLVAEGVRLIGGCCGTTPDHIRAVKRSIRGLKPIERKVVTPI
IPVKDFVRRIRRTDTLVDKVKKEVTIIAELDPPKHLDIVQFQKAIRAIDQKGIAAITLAD
NSLSNTRICNLSIASLLKDEISTPFLLHIACRDHNLIGLQSRLLGMELLGFNHILAITGD
PTKLGDFPGATSVYDVTSFKLLSLIKQLNQGLSYSGASLRRPTDFTVAAAFNPNVKNLTR
TVKLIEKKVASGADYFMTQPIFDHSVLKELADLTKTVEQPFFIGIMPITSYNNAVFLHNE
VPGIKLSESFLSALEKVKDDKEACLTLALNESKSLIDEALNYFNGIYLITPFLRYDLTLE
LIDYIQKKQVRKSS
>A0A2A5DWK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTIHGSPSGPLPFVPTRHPAPQLSFEFFPPNTETMTARLWETVLRLAPLHPRFVSVTYGA
GGSTRQRTHETVTRIQRETDLEPAAHLTCIDATREEVDAVARDYWAAGIRHIVALRGDPP
EGAPRYVPHAGGYAYAADLVDGLKRIADFEISVAAYPETHPEAKSEQADLDNLKRKIDAG
ASRAITQYFFDVDVYFRFLDRVRDAGITVPIVPGIMPVSNFAQIVRFSAMCGTTVPSWLC
ELFEGLENDPETRKLVGATVAAEQCRLLQAQGIDAFHFYTLNRADLTYAISHVLGARPSP
QAEKTP
>A0A552ED80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa Ma_MB_F_20061100_S20D|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>A0A2E3S089|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSKTNVSFEFFPPASEKMEKSLWKAAGLLAPLKPKFVSITYGAGGSTRDRTHLTVKHLQE
MTGLEPAAHLTCVGATIEEVNTVIRGYWEVGVRHIVALRGDPPNGTSGRYKPHPSGYENA
AALTAGIRGIGDFFISVAAYPETHPESPSPAADIEMLKRKTEAGAKQAITQFFFNPEHFF
RYRDQVAAAGISIPIIPGIIPVFNLARIKSFAAKCGTEVPSWLDERFIGLDDDVASRKGV
AADIATELCQELRSEGVEQFHFYTLNQADLTLEICRNLGVNCDPRG
>A0A2P5LUJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp|TrEMBL
MNAVPARSSRQTEAPKLGISFEFFPPKNDAMAETLWASVQRLAPLSPDFVSVTYGAGGST
RERTHSTVKRILDETGLKPASHLTCVAATRDETDEILRQYWAMGVRHIVALRGDPITGIG
TTFEAHPQGYQGSPELVAGIKAIGDFHVAVSAYPEKHPESPSLDFEIDLLKRKVDAGADR
AITQFFFDNSHYYRYVERVRKAGISIPIVPGILPVQNFRQSASFATKCGTDVPAWLAKRF
EGLEDDPETRRMVAAAVAVEQVYDLLDNGVTDFHFYTMNKADLAFAICHMLGLRAMPGMR
PGIPDAA
>A0A3A4N5H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pseudopneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQILDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A0E3Z6N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lomondensis|TrEMBL
MAERARKDPAKLIAAGHRSYSFEFFPPKTGKGQRALWDALRRVEPLNPSFVSVTYGAGGT
SRERTTALTQRIAEDTTLRPVAHLTAVEHSMAELRAIIGRYADAGIRDILALRGDPPGDP
QGPWIPHPHGLRHAAELVELVRQCGTFSIGVAAFPERHPRSPDWDTDIRHFMAKCRAGAD
YAITQMFFRAEDYLRLRDRLAVAGCDTPVIPGIMPATRYEQIARFALLSNATFPDDLALR
LRTAQCDPGESRRIGVDHGTELAQRLLDEGAPGLHYITLNQSSAAMDIHRGLRLPAPPRN
PEAST
>A0A396GGU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Medicago truncatula|TrEMBL
MYVYQNAYLEFFCSKEKLDALIEKSKDRPFLTYMAMNKEGIWKSNAGQTDVNAVTWGVFP
AKEIIQPTIVDPAASTCGRMRHLKFGQEDGQAYTLMLMHPGNWLKRWAAATSWSAWWTTI
TSMVIFLVC
>A0A433AWI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp|TrEMBL
MEFGPCGGVRPDGQCEMRSGACTFIDIVPWSGPTPVPRRASASAPLVLTDFSCTPFDRDD
VAATAAVLASSCDAVLVGEHQNRPDFPPTLMGSLLLDAGVTPWITLSCRDRNRIVLEQEL
RGLRTIGVDTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASLGAVPAVPETPTAPPV
HARPARLVEKQRAGARLAVLNHVPFPDMIADFMKIARSQGLSIPVIAAVAVFTDTVSAAV
LEGLPGLELDPAVTERVLSSADPIAAGISAAVSEARSLLTIDGVVGVNVSGLASASGTRV
GAEIKAEVGRLIRKEVL
>A0A0P7XEH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus marincola HL-49|TrEMBL
MKITDHLKNAKSTLFSFEILPPLKGQSLKELLEGIEPLMEFKPPFVDVTYHREEYIYKKH
PSGLLEKVSTKKRPGTVGICAAIMNRFQVDAVPHLLCGGFSKEETENALIDLNFIGVENV
LALRGDAPKTEGKFIAEKNGHHFASELVDQIIRMNQGKYLHEEMEASFHTDFCVGVAGYP
EKHFEAPSMKFDLKYLKEKVDRGAEYIVTQMFFDNEKFFEFERNVRASGIDVPIIPGLKP
ITTLSQITMLPRTFFLDLPDALTDELLKCKTNAEVKEIGIEWAIQQSKELVKAGVPSLHF
YTMSKAEATYKIAKEVF
>W9RM75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morus notabilis|TrEMBL
MKVIEKIQEALLNEKKVVFSFEFFPPRTEDGVDGLFEKMERMAAYNPAFCDITWGAGGST
AELTLDIAAKMENMVCVDTMMHLTCTNMPLEKIDHALDTIKSKGIRNVLALRGDPPRGQD
KFVQVQGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDMIGSCGVPTLEGYHKDLAYL
KRKVDAGADLIITQLFYDTDIFLKFVNDCRQVGITCPIVPGIMPINNYKGFLRMTGFCKT
KVPAEIAAALEPIKDNEEAVKSYGIYLGTEMCKKILAHGIRTLHFYTLNLEKSALAILSN
LGLIEEAKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYLSRTTDWDQYPNGRWGDSLN
PSYGAITDYEVMQSRARGKRLLEEWGVPLRSSEDIHEKFKEFCVGKLRSSPWSEFDGLQP
ESRIISEQLMKINMKGFLTINSQPAVNGERSDCQTVGWGGPGGYVYQKAYLEFFCSREKL
DSLVEKSRAFPSITLMAVNKEGSWISNIGHVDVNAVTWGVFPGKEIIQPTVLDPSSFIVW
KDEAFEIWSKVWASLYPEGDPSRNLLEQVRNSHFLVSLVDNDYIHSNIFSVFSDF
>A0A428RNU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium floridanum|TrEMBL
MHIKEMLTDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRDQDK
WTAADGGFQYARDLVKHIRSTYGNHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKKVRERGVNVPILPGIMPIATYASFLRRANHMKAKVPQAWLDAL
EPVKNDDVAVRDIGKSLVAEMCRKLLANGIHHLHFYTMNLAQATRMVLEELNWAPSAERP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTVQDIAQLFVRYLRNEIDSLPWSESPLTSEADEIRDDLVE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPSNGYVYQKSYLELLVHPDVFNDMIGRIEGHP
DLTFYAVTKDGELRSNAPSDCPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDASSPSRALIDEVMNEWYLVNIVNNDFHQNGTIFELLKGLEVKDLTTPATPKSEPE
ANGTEPLANGAAAA
>A0A2E7BC81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MASTIEMISKAATDWSIEVTPTGANKIESFRDCLPPGTTVNVTFLPGTDPAETIAVAERL
HNDGMRPVPHLAARSLRDADQLDELLTAFTSRCGVDEVLCIGGGVDKPVGTFDATIQVLE
AGLIQKHGIRSVGVAGHPEGSPDISDEEVAEALAAKNALAARDGLNLYIETQFCFEADIV
LDWERRVRAAGNTLPIRIGIPGPATIKTLFRFAQISGIGPSMRFIAKQAKNVAKLMTVQS
PHMLIAGLAEGMAADXACLIRHFHYYPFGGFARTAAYAGAIAEGNIELLPKGGFDVIAN
>A0A3A8LJ77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus sp. CA047B|TrEMBL
MKIRNCLNPSQPCFSFEFFPPKTDAGVASLLRTVEELAPLNPGFVSVTYGAGGSTRDRTV
DLVTHIKKHTGIEAMAHLTCVGHTRDELRDVLRRLDAARIENLLLLRGDPPQGQQTFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRMIVSALRARS
>A0A2E6RSP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MDNLHKNINKLSESLLQKKFVITAETTPKTNTDLNASLEKVLCLKGLADAVNITDGAGAK
SHLSSLVLSGAMKSNGIEPIIQLTLRDRNRIAIQSDVIGAAAMGVKNFLVLTGDPAEVGD
EKDAKFVGDFDGSTGLISLLEKINNTGELNSGRKINNPPEIFLGAADAPFLPPSGWKPDK
LIAKIDSGAKFFQTQYCFDMKVCKKYFSILSDFGLLESVYFLVGIGPFSSSKQAKWMHEN
LPGVEVPDKVLNILSKSKDEKKDGKKICLELLDELQEIDGVSGAHIMGPGQEQTVAEIIQ
AKRK
>A0A3R6GU58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. AM23-20|TrEMBL
MRLTELLNTENVTISCELFPPKQGAQLDNYKKIVGDMAALKPAYMSVTYGATGGTSDYTV
ELANEVRNVNHIPALAHLTCASSTKEKVASVIQELKEKQIENVLALRGDIPQNADFPLPN
QYKHASELIYDIKSQGDFCIGGACYPEGHPESQTLEEDLIHLKEKVDAGCEFLTTQMFFD
NNILYNFMYKALKHGIDVPVVAGIMPITNANQVKRSIALSGSLVPRRFLAIVDRFGSDPA
AMKQAGIAYATDQIIDLIANGVNHVHIYTMNKPDVAGAILENLSDIYVRD
>A0A1G5Z9P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus alkaliphilus|TrEMBL
MKITERLKNTTSTLFSFEILPPLKGQSLKELLVGIEPLMEFKPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFQVDAVPHILCGGFSKEETENALIDLNFIGVENV
LALRGDAPKSEGRFIAETNGHNYASELVEQIVRMNNGHYLHEETENSFHTDFCVGVSGYP
EKHFEAPSMKFDLKYLKEKIDKGAEYIVTQMFFDNQKFFDYVRRVRAAGIDVPIIPGIKP
ITTLGQITMLPRTFFLDFPDELMDELEKCKTNADVKTVGIEWAIQQSKELIAAGVPSLHF
YTMSKAEATYKIAKEVF
>A0A1G0Y8B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium GWF2_49_21|TrEMBL
MKQSLEKTLASRISIFDGAMGTEIYKRNFFVNTCFDELCLSAPKIIGQIHKEYSDAGADV
LTTNTFGANFNKLSHFGLGDKVREINKVAVKLARENGKDDTLVAGSVGPIGKIHHHEKNS
AEQVVEMLAEQISALEEAGADFIIFETLPTVADAEFAFRAVNKNSKIPYVLSFTLDDNSE
TVKGEPVQSLINVFKDGTRKPAAVGLNCGAGPEGMLSSVEKLVQQTNLPIIVQPNAGMPK
NVGGRLIYMASPEYFTTYAIRFVNMGVRGVGGCCGTGPDHIRDIARSIRPLAKTAALEKI
IVKTLEEHLQAPVPMEKKSRLAAKFAKGEWIATVEIVPPKGYDLEQTIQKSKQCKDAGID
AINIPDGPRASSRMSPIVTAAKIQQEAGIETILHFCCRDRNLIGMQSDLLGCAALNINNI
LFITGDPPKLGDYPFASAVFDVDSIGMAKIQSRLNRGVDIGGNSIKEPTKALIGVGADPN
AIDMEREIRRTREKIAAGAEFIITQPVFAVEPLIKFIEKISDLKIPVIAGIWPLASFRNA
EFMKNEVPGVVVPDSIMDRMAKAKTKEEQRLEGIRIAKESIEKIRSHIRGIQVSAPFGNV
QTALEVIK
>A0A1G3ZI62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium GWF2_62_7|TrEMBL
MTDARDSLTFREMLGSGQFCYGAELVSTRGITAPGERPKLVELGEALAADKRIAWVSITD
NPGGNPMLPPDWIAQKLAAHRDRVVIHLSCKDLNRNGLESAAWRYAQEGFDNVLAMTGDY
PVTSYGGLARPVFDLDSVSLIALLKAMNDGLEVPKPSGKLERLPKTNFYIGCAVSPFKRY
ERELMPQYFKLARKIHCGAQWVISQLGYDMRKFHELKLFMEWARVQAPLIGNVYVLNKTV
AGMFHKNKIPGCVVSDRLYELVEKYAAGPDKGRAFFLELAAKQLAVFKGMGFAGGYLGGI
HKADAFGQVIEMAEKFGGNDWKALAKEIQFPKPDEFYLFEQNPETGLGDITQLNRAYRES
LLHPPKSPHANLAYRLTRRVHELAFTRGKGMFPSLQKFYERLEKNGDNLASRALHAIERV
SKEMSFGCKDCGDCSLPDTAYLCPRASCSKTGRNGPCGGSSDGRCELDDKECLWARAYER
LKYYGESGHMLDGPAVFYNAKLEGTSSWANTFLGRDHHRAVPAEKEKQKETFAKAGQL
>A0A7Y8Q2G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. SwsAc6|TrEMBL
MSLLSSYFQQNQFCILVEYLTSLNEIFPVKKQFAGYPAVMTLADRVHSDHDTSPLEASKL
YPQDLEKVLHFAGKGRDIHDFENFLKQARKADIQNLLLLTGDKLKEHSNGENGTARSRYL
ESVNAVMAAKKAGGFCIGVAFNPFKYTEAERDAQYLKLHKKIKAGADFIITQLGYDIQAL
KQAKAFLTQHHYSQKILACVMPLSLARAKFMLKNQVAGIVITPYMLKVLEEEKQAGLSER
VYLRCALQILICKQLGFAGVDLSACHKPAEQALLESYIEQYRHLNLDALEKLWNELWQIH
TGAEFQPELSYFSRPPSSRQLFKYHQLHLMHDALFDSKLGKGVGRFIFKAQIWQKATAAK
TLLKTEYISKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVQQTQVLKEKLIPTVPIEVRGTSSWKNWYLAAEA
>A0A1H7XV22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. cl141a|TrEMBL
MKPNLRQAWENQVLVGDGAMGTYLYQKGFPVGISYEELNLTSPEVIGNVHRQYVEAGAQV
IETNTFSANYDKLSKYGLEARVGEINRAGVRIAREAAGDQGYVVGAVGSIRAGKRSNIST
SELKRYFEEQLSVLISEGVDGILLETFYDVDEMQLALAQARMLSDLPVICQFAVEDIART
LDGFTMPDAYRILSQEGADVIGFNCRTGPNGIMRALETLNGIMNLPASVYPNAGIADYVD
GEYRYGASPEYFGKTALEFADRGARIIGGCCGTTPEHIAEISSALSGYVPSPLPTVEEAE
INRIVIHETAQEQFYERSGEPTIVDIVKERHTVIVELDPPRDLDITKFMKGAEALKKAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPDSSSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVVGAAFNP
NVRHLDKAVARLEKKIASGADYVMTQPVYDPELMVRLREATAHLDIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAMGVKIGKELLDVATEHFNGIYLMTPFMFY
EMSVQLMEYVWEKSGRRLTPLFH
>A0A7X7RCQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MVQQTRQLNMSFEGDCRLASAMRSGQFCLLLEMNSPPSNQPLDSYMAAATPVFKQVGMLP
GVHGIAVTDRWPTVQRQDPVDFAAQAMKGSGKPVLMTLSGRGTDLARAKTLLAEARAKGI
RCFLAVTGDWLGKNGAEDVPTTYLDSVTTTVTACQFGSDAWVGAAVNPYKYTCEGVFLQY
AKLQRKITHGADFLVAQVGWDMKKAQELQWFLQMRELYRPTLARVVLMNQDDALKLGEGF
WPGVPMPIPLGALIMREAAGTADQFLEAQLSRTALQIVGFRLLGYSGVQVSGVRTPNLLA
QLVDRVHDCTAECPDYDAWLEAWRQRHGDISFGPGASDLCPDPPYYLFADLQQPGRRDFD
PELAQVSFNTIAPPTLGDRWTRWLHRPTRPRLIREAVRRLTFRSEVDEAAADLCQGLLNR
SCPKGLVYGACGGASTDGRCEDGNLECFFHRVIRLASAANDLEALENGEVAP
>A0A1R0Y6H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus odorifer|TrEMBL
MKPDLRSAWGNKVLVGDGAMGTYLYQKGFPVGISYEELNLTSPGVIEDVHRSYIDAGAVL
LESNTFSANFDRLSKYGLESKVEEINRAGVRIARKAAGDTGYVLGAVGSIRAGKRANLSS
TELKKYFTQQITALLEEEVDGIMLETFYDVEELHLALRTVRKHSTLPVICQFAVDESART
LDGLTLPEAFRILEGDGADIIGFNCNTGPNGIKRALKAVQGNLVLPTSVYPNAGVADYVD
GEYRYGASPEYFGQMAVTFAEMGCRIIGGCCGTTPQHIAEISSALKGYEPQPLPKPSLVT
VERVSLQEHFGEDEGRDGREPNLVDLVKERHTVIVELDPPRDLDIAKFMQGAEALRRAGA
DALTLADNSLAVTRMSNMALGHLVHAKTGLRPLVHVACRDRNLIGTQSHLMGFDALGIDH
VLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGISFSGKPLKQKANFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDQELIVKIAEATAHLEIPVFIGVMPLASGRN
AEFLHNEVPGIQLTDEVRNRMKGLEGEAGRAEGVAIAKELLDVATAHFNGIYLMTPFMFY
DMSAQLMEYVWEKSGRKLSPLFR
>A0A1E3H158|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobrevis pamukkalensis|TrEMBL
MSPIRNPESLDLGVSFEFFPPKSEKMEETLWASIERLAPLGPRFVSVTYGAGGSTRERTH
NTVARILRETQLKPAAHLTCVDATRARWTR
>A0A1M7Y3G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila aestuarii DSM 18488|TrEMBL
MKAGSNLEKVLAAGHFAVTAECGPPRGADAEIVRKKAAFVKGNVDACNVTDNQTSVVRMS
SLAGCLLVKECGTEPLIQMVVRDRNRIALQSDLLGASAMGVKNLLCLSGDHQKFGEDPQA
KNVFDIDSIQLIHMVKTMRDEGIFPSGKKLEGEPKFYIGCAVNPFADPYEIRVPRFKLKV
DAGADFVQTQCIYNMAKFKQYMEDAKKMGLHDRVKILAGVTPLKSAGMAKFMKKFVAGMD
IPDDVIKRIADEPKEKQAAKGIEMCVEQIQELKEIEGVAGVHVMAIEWEEKLGKIVGDAG
LLPRPHVD
>A0A518L1R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium TBK1r|TrEMBL
MSSPIKLADHYNGEQCAISFELFPPKTDAGMDLLEKNVERLKAFQPSFFTCTYGAGGSTQ
SRTLDVVQRVRELTGLPVASHLTCVGSTVGQLGEYLAEAKRRGADYIVALRGDPPKGSES
FQAVEGGLRYANELVELIQERFPDQFGIAVAGYPEVHQEATDAQTDLDNLKRKVDAGADV
IVTQLFYDNDDFYRFRDACQAAGIRVPIVPGILPVTNYKQALRIAGMCKARIPDQMAAAM
NENDDADYQFKVGVDHARVQTIDLIENGVPGIHYYVLNKSDAAGQMLDGLSLGMQS
>A0A4V1KI23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcticibacter tournemirensis|TrEMBL
MKITEHIAGANGKALFSFELLPPVKGQSIQQIYNAIDPLMEFKPPFIDVTYHREDYIYKQ
HPTGLLEKVTYRKRPGTVAICAAIINRYKVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKADPAFMPTPGGHSYACELLQQVVNMNNGKYLHEDHDSNKTNFCIGVAAYP
EKHFESPNPETDFKYLKQKVDMGADFIVTQMFFDNQKYFSFVNRCRENGINVPIIPGLKP
ITTSKQLINLPKIFHIDIPLELSEAVSACKTEKDVKDAGIEWMIHQCKELIEFGAPVLHF
YTMGNPEPTYRIAKEVF
>A0A1F9BYF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_49_23|TrEMBL
MKAGSNLEKILSKDLFAVTGELGPPKGNDVSVIQRKADLLKGYVDAVNVTDNQTAIVRMS
SIATSSLLIQMGLEPVMQMVTRDRNRIAIQSDLFGATALGIRNMLCLTGDHHTFGNQVDS
KNVHDLDSIQLIDCVRTMRDKGTLLGGEEKIEGEIKLFIGAAENPFGDPFEFRAIRLAKK
ASAGVDFIQTQCIYDMTRFKEWMKMVRDRGLHEKVHILAGVTPLKSGGMARYMAKNVSGI
IIPDQIIDRIVKAKKPAEEGIKLCVEQIQELREIEGVHGVHIMAIEWEQMTSQITEMAGL
LPRPQIT
>A0A1Q3RCE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium 64-34|TrEMBL
MIAANAQGTGFPVSFEFFPPKTPEGADKLRAARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREQLAMLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPEADLNAYIAKVQAGADSAITQYFYNSD
AYFRFVEDTQRLGANVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A0R0D106|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas chelatiphaga|TrEMBL
MTSLSFEFYPPKTDEQRSQLDRTAAKLRGFGPEYVSCTFGAGGSTLSYTSETVRHLKQHH
RFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYAAELIDFI
RAEHGNAFRIEVGAYPETHPQASDALADLKHFKAKVDAGADAAITQYFYNADAYFHFVDA
VRALGVSVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGRKMQAYGDDSDSIRAFGAEVV
AQLCQRLVEGGAPGLHFYTLNLAKPTTSVLKLLRS
>A0A126ZFN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. PAMC 28711|TrEMBL
MGLPLSFEFFPTKTPEGAVKLRAVRQQLYVHKPEFCSVTYGAGGSTHDGTFNAVREILEE
EVDAASHFSCIGATKATVRTQLAELKAMGVKRIVALRGDLPSGYGIGGEFHYASDLVRFI
RDETGRDFHIEVACYPEVHPQAKSPEADLQAYAAKVRAGADSAITQYFFSAEAYFRFVNE
SRKLGLDVPVVPGVMPIISSTQLMRFSDACGAEIPRWIRLRLQSYGDDIASIKAFGLDVV
TDLCQRLRAGGAPALHFYTMNQAQATLGVLERLG
>A6Q4K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratiruptor sp. (strain SB155-2)|TrEMBL
MFEALVEKLRSGRYVSLETTPGHLPTVENIIQKIEQHRLHEKVDAFTTTDNPLAKLKYNA
ILAAIRLQTKFKKPVIATMSMRDRNKIALQSDLLGANDFDIRAILALTGDPAKISDQPNT
KGCFEGDSTLLLDIIKCFNAGIDYAGKEFSIKPKKIYPFAVSNSYAKNPKTLQRKFFKKI
EHGAVAIITQPVYDRNNIMLLVELFEEIRSQFQNDKAKSQLILGFFPITKLKTAQFLASH
VPGINVPRFWIDELYKAHKDGERKEYEVGMALSRDLFETIMNIHPKVHIMTANRFEVANE
ILS
>A0A4U1VYZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. F12|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSNEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A3N4NBW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria sp. 10009|TrEMBL
MSYAKEINALNNSLCDLKGDINVSFEFFPPKNEQMETMLWDSIHRLKNLHPKFVSVTYGA
NSGERDRTHGIVKNIKQQTGLEAAPHLTGIDASPEELKQIAQDYWDSGIRRIVALRGDEP
AGYAKKPFYAEDLVKVLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVESYLRFRDRCVTVGIDAEIVPGILPVTNFKQLGKMAQVTNVKIPNWLARMYDGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHTLGVRPLPNAA
>A0A2P8Q726|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces dioscori|TrEMBL
MALGSASTRTDRARTVRDMLATGKTTFSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGTTRAGTVKATEQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMADWVAHPQGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDADVANFVD
KCRAGADYAITQMFFRPDAYLRLRDRVDAAGCATPVIPEVMPVTSVKMLERLPQLSNASF
PDALKERILTAKDDPAAVRSIGIEFATEFCATLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A366XHG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrionales bacterium C3R12|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLVAAPHLTCIDASREELINIADDYWNNGIKNIVALRGD
IPAGGGAPDMYASDLVKLLKSQHDFDISVAAFPEVHPEAKSAQADLINLKRKVDAGADRA
ITQFFFDVESYLRFRDRCVAAGIDAEIVPGILPVSNFKQASRFAAMNNVKVPGWMAQQFN
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPA
>A0A323V139|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azoarcus communis SWub3 = DSM 12120|TrEMBL
MHNTELSIEFFPPQTSEGAEKLRGVRAQLAELKPSFFSVTYGAGGSTRERTFATVKEIAA
SGCEAAPHLSCIGSTRDGIREILNEYAEAGIRRIVALRGDLPSGVGDPGEFRYANELVAF
IRSETGNRFRIEVAAYPEWHPQARSPRDDLLAFKRKADAGADSAITQYFYNLDAYLHFVD
EVRAMGVDIPIVPGIMPIASFSKLARFSDACGAEIPRWMRKKFEAYGDDADSIRAFGLDV
VTEMCEKLLAAGVPGLHFYSMNQAALTTEICKRLKLA
>A0A4Z1D6S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces bauhiniae|TrEMBL
MALGTASTRTDRARTVRDILATGKTAYSFEFYAPKTPQGERNLWNALRRVEAVAPDFVSV
TYGAGGTTRATTVKETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPEGLRYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEILPVTSVKMLERLPKLSNALF
PPELKERILAAKDDPAAVRSLGIDFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A7C4K4T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPIFTPGRRWQPPFMPFKREPFGRRLLASLEKMIKGPLFGCRMCGNCLLQETAFICPMEC
PKGARNGPCGGSTPEHCYVDETRPCMWYQIYDRAFKMGRQEMLLEVLPPLDWDKVGTETW
GDVVAQVRKIGTAKVFSGLLARDPVTRTTTWDMIFRPVRQPEWWKGDAEYHPPQYTEPVS
KLEERLKAGEFVVTAEVAPPLTTSTSKLCSNVEMVKPYVTAINFTDCPSATPRMSSWACS
TLAVQQGAEPVMQIAARDRTRVGLQAEVLGANALGVRNILCLSGDSMRLAPEPRGRMDVI
DLDSIQMLWILRRMRDEGVYLDGRSIKFPPKYFLGAAAAPFASEPRFQAIREHKKVNAGA
QFFQTNLVYDPDGMEVWLNELAKRNILDKVYILVGITPIKNYKIAKYMNDEVPGVFIPDA
LMKRMEKAEEAGNAQEEGVQIALEIIEKIKAKRGQGIHGIHIMAVGWEEIVPRLVTEAGL
LPSDFVAPAPVEKASAQV
>A0A838MXV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrinomonadaceae bacterium|TrEMBL
MENFRDILASDQITVFDGAMGTMLYAKGVYINRSYDELNLTNPDLVREVHEEYVRAGAEV
IETNTFGATAPHLQQFGLEGNLRLINVAAARLAREAAGERAYVAGAVGPLGLRIEPYGPT
SFDEAKDLFKGQIAALLEGGVDLFVLETFSDVSEIRQAIRAVRELCDLPIVTQMTILPDG
NTSFGTTPEVFTTRLDEWGADVIGLNCGVGPAIVLTAIEKMRVLTDKKLCAQPNAGLPRD
VQGRQFYMCSPEYMAKYAKRLIQAGVKMVGGCCGTTPAHIKMITDAVRAVSPRKSRVFLK
SEQPARVEELTPADIRVVPPEERSNWGRMITNGEFVTTVEVLPPKGCDAKKTLDQIRLLK
EVGVNAVNIPDGPRAQTRMSAQATALLVEREIGLEAVLHYCCRDRNLLGMMSDLLGAAAL
GLRNLLLITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGCPTSFCIGV
GVNPGALNVEEEIKRFEYKVEAGAEFAITQPVFDAAQLRDFLKMIQHVRIPVVAGIWPLV
SYRNAEFLHNEVPGVRVTPSIMERMQRASDKSKDHARDEGLQIARESLLEVRDLIQGVQV
SAPFNNVRLALEVFDALPELSERREADVTALIR
>A0A7V4J6B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MSDASVNGHKCGSNLERVLAAGHFAVTGELGPPKNHDAGVIRHKATLLSGCVDAANITDN
QTAIVRMSSIAAGAILLQVGLEPVIQMTCRDRNRLSMQGDLLGAAALGIKNVLCLTGDHQ
SFGNHPTAKNVHDLDSVQLVQMVRDMRDAGRFQCGEEIPGGGPRFFIGAAANPFGDPFEF
RPYRLAKKVSAGADFIQTQLIYDIPRFREFMKRVVDMGLHERVAILAGVGPLKSVGMARY
MRDEVPGMIVADEYIERMEGAVKGIDKADKKARAEAARQTGIQICIEQIQQIREIEGVAG
IHIMAIEWEEAIRPIVEGAGLLPRPQLADAPA
>A0A7C4MRU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MLSAQVVAIDGQRAVEQRAGVETLLHYTCRDRNLLGMQSDLLGAHAMGVRNLLITTGDPP
LVGDYPQATGVFDVDSIGLANLVTRLNQGYDLGG
>A0A8G0JWQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. polymorphum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHFTCIGSKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEPGD
FNYAKDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A3A0CIA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MEPFLDALKKRVLIGDGAYGTLFSRRGLSSPGLVSPLLNLAKPGFVKAIHEEYLRAGSEV
LETNTFGASRPVLEAAGAGDKAREVWRAGARIAREAAAQKAYVLGSIAPLGRAGLKLTPD
QRQAAYAEQVQGLVEGGIDAVLFETFSDLEDLQLAIIAANQAAPDTPVVAQMAFSIAGTT
TSGVSPESMIEGLKELRVSMLGANCGGGESAAIEVVRRMADHTDKPLSVFPNRGLADFDE
TGRPVYIEGADYFAKSARRLADLGANLIGGCCGTGPEEIRKLKGLLAGRRPSVRHKAVSS
SSGRRQAAVPPGPRVQKTLAADFARGGVVIAEVDPPRGIDATEQMAGARLLMEAGIDAIT
IADNALSVMRMGNLALAQLFMAEFKARIVLHVACRDRSLLGTQSHLLAAYALGVSNVLAV
TGDPIATQAHQGSSGVFDMSSTKLIELISRINRGEFTAESDGELRTNFYIGAAFNSATRS
LENESKRLMRKQQAGAGFVMTQPVFSVESARAVAAAIAPLNMPVALGIMPLVSERNAEFL
HNEVPGIQIPEAIRGRMAGKSGKKGRAEGLAIARELMEQVADSVAGFYLITPMDRYEMIA
ELTTFARSLRVKARA
>A0A7V9HX64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrinomonadaceae bacterium|TrEMBL
MQTFRDLLENDRIHVFDGAMGTMLYAKGVYINRCYDELNLSNPDLVREIHSEYIHAGADI
IETNTFGATAYRLHQYGLEGSLEEINIAAARIAREAGGEDAHVAGAIGPLGLRIEPYGPT
SFDEAKNLFRAQASALLEGGVHLFLLETFSDVSEIRQAIRAIRELCDLPIIAQMTIMTDG
NTTFGTTPEVFTARLDEWGADVIGLNCGVGPAIILSGLEKMRTVTKKKLAAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRLIQSGAKFIGGCCGTTPAHIKLISDAVRAASPRAQRMVMS
SGPLVHVEEIVPADIKIVPAEERSNWSRKIVRGEFVTSVEVLPPKGVDAGKTLDSIRLLK
DAGVDGVNIPDGARAQSRMSAMATAVLVEQQIGIESVLHYCCRDRNLLGMMSDLLGASAL
GLRNLLLITGDPPKMGPYPDATAVFDIDAIGLTNMVNKLNHGLDIGNNPIGQPTAFCIGV
GVNPGAINPEEEIRRFEYKVEAGAQYAITQPVFDTDQLRDFIKSIEHVRIPIIAGIWPLV
SYRNAEFLHNEVPGVRVTPSIMERMRAASAISKEAGRDEGLKIARESLLEVRDQIQGVQV
SAPFGNVKYALEVFQALPAFDAQAEGV
>A0A7C3IW16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MKSGSNLERVLAAGHFALTAELGPPMSADANEVRHKMKLLRGSADAYNITDCQTAVVRLS
SIASAIMLIQDGMEPVMQMTTRDRNRIAIQADILGAAAFGIKNCLCIAGDHQSFSAAGRL
KGHPGAKNVYDVDSIQLIAILKKMRDEALQEGGDPLTVPPKLFIGAAWTPMGDPMDFRVL
RLAKKVAAGADFIQTQGVYDVELFAKQMKEARNLGLHEKTAILAGIIVPKNAGMLRYMNS
SVAGVKVPEALIARFPKPPKKDASKEEKKAAAAEAERIGKQIAVELIQQCREIEGVRGVH
LQAIEWESAVPEIVKAAGLLPRPVVPAEPAQA
>A0A661U9E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Coatesbacteria bacterium|TrEMBL
MQESFLDAVQNRVLVCDGAMGTMLYSKGVYINQCFDELNLSAPHLVSEVHAAYLKAGAVI
LETNTYGANRHRLAPYGLEAKTRDINRRGVEIAKQVARGRAYVAGSIGRLKSTVLLKDML
TSDDIKSIYAEQAASLANAGADLILIETVSSFKMMSLAIQAVREVCDLPLVAQMTVTEDG
STIYGDEPEEIAVFLRDQKVDVGGLNCSVGPQQMLAAIERMAKTEDLLISAQPNAGLPKL
VEGRYIYLCSPEYMAEYARRFIAKGASIVGGCCGTTPAHIKAIADAVKSERGIAPEVFDV
QFEVEPEERERVEVSREPTRLELAMKDHFTVSVEISPPRGIGIDRIIDRATSIKDAGVDA
INIADGPRASARMSPILLGHIIEERVGIDTIVHFCCRDRNIVALQADLMAAHVAGLRNVL
LVTGDPPKVGDYPQSTAVFDIDSIGLSAMAQNLNCGVDLAGKPINQSTEFFIGVGVNPGA
MDLEKELARFAAKGRAGAHFAMTQPVYEPRILERFLEQSSDVDLPIFVGILPLISYRNAE
FMHNEVPGMSIPKGVRERMRRARTGDEAKREGVAIAADALQSVIGMDRVVGAYLVPPVGR
IDLALQVIERVQLPSSP
>A0A7Y5QCP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPLLTPGRRWQPAYFPFKREPLSRRLLAALERAVKGPLFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGSLPERCYVDETRPCVWYHIYKRSEAMGRSDKLLEVLPPLDWDKVGTETW
GDIVSQIRRVGVRRTVGGLTSRDPSRRAAAWDAIFTPVRQPNWWQGDALYHPPAYQEPIS
ELERRLRAGEFVVTAEMTPPLGASTDKLVETLASIRGWVAAVNFTDSASAMPRMSSLACS
AIAAQQGVEPVLQIAARDHTRTGIQSEIMGANALGIRNVLCLSGDHARMGAPPYGRSDIV
DLDSVQILWMLRRMRDEQMYLDQRAIKTPPRLFLGAAASPGASEARFQALREQKKINAGA
QFLQTNLIFDIERLEIWLDALARRNVLDKVHIIVGVALLKSLKSAQYMHEHVPGVRIPET
IFKRLEAAGDAAGEEGVQITLELIAAVRRFPGIHGVHLVTIGRESLLPRIIAEAGLASQI
GVATMG
>A0A800BRX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MKAGSNLEKVLEAGHFAVTAELGPPKGTSRRVIERKAELLKFCCDAVNVTDNQTAIVRMS
SWAACVILKQQGVEPVLQIVTRDRNRLAIQSDVLGAIALGIRNILCLTGDHQRLGDHPTA
KNVYDLDSIQLVQTLKRMRDEKKLLSGSDIRGEVPIFIGAAANPFADPFEYRVIRLAKKV
KAGADFIQTQAIFDVDRFDRFMRMVRDRGLDEKVHILAGVIPTKSAGMARYMRDYVAGVI
VPDEIVKRMEDAKDAKAEGVKICLEIIERLLEIPGIHGIHIMAVGWEDIVPEIVERANLL
PRPML
>W9CEU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sclerotinia borealis (strain F-4128)|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRAVDEKNGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPSLVEKVQAGADFIMTQLFFDVDAYDTFEQRLRDHPSGAFKTLPIIPGMMPIQSYQMI
KRTTKLSHAVLPTNIITRLDEVRGDDEMVKKVGVDILSEMVEHLKVTKSQYSGPRGFHFY
TLNLEKAVSFILERTDLIPDAEAVAALESEYTPTIPDIADLMSIRSGSHKRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EALNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSNDSIFGWGPKNGFVFQKAFVELFI
PASDWETLHTNLTSPALRDTVSFYASNAKGDFISSDEGVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEESFGIWGEWARVYGKDSATRKVIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLQ
>A0A8B3CC52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. AF48-12|TrEMBL
MHITDIIRKAGAEGKPRFSFELLPPLKGDGTQRTFEAIDPLMEFSPIFCSVTYHREDVKY
VEKENGLLERHTVRRRPGTVGISAAIMQRYGLTVIPHLICGGQSRYDIEDALIDLDFLGI
QNVLALRGDNLKGEHTFRNHPDGHLHASELVEQIERMNRGVFIDGEVEQCHNTNFCIGVA
GYPEKHAEAPNKAEDLRRLKEKVDAGAAYIITQMSFDSAKILSFIDDCRAAGIDVPIVPG
IKPFSTKAQLTMLPQIFHVDLPEALVETVKRCNNNAEVREAGVEWAIAQGRELIAAGIPV
LHFYTMGKTDNMVKIARALF
>A0A7V4J4L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPLFSPRRYQAPFIPVQRESFPMRVFTGFEQAIKGVMFGCRMCGNCILQETALVCPMTCP
KGLRNGLCGGATPDHCEVDPTRPCTWYVIYNRAERWGWEHKLLEINAPVDGTRAGRETWI
DMVKLWFSRKAGPYPWDFVLNRDKFKREWDAFFYALRQPAWWQGDSAYHPPAYTEPISRL
EANLRTGVFTTTAEIAPPLDASPAGIVKKVEMLKPYVTAANFTDNASSTCRMSSMASSKI
CLDAGLEPVMQLQARDRSRVVIESDAVGAAGLGIRNILCLTGDHHRFGPTPWSMPDQFDL
DGIQTLWMLRRMRDEGKYIDGREMKVRPQFYLGAAASPFGAPPKYEAIRAEKKVNAGAQF
IQTQPIFDYNRFTEWLEALDKRNLLDKVHILAGIVPLRSARAAHFMTEVPGVVLTDQDLK
RMDAAGDKDAQAETGVAIALEMIERLKNTPGVRGLHIMAVHWESIVPRLVEESGLPRPVV
TELPQPAAVPKPESVPASQPA
>A0A4Q6AFX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIEHINEAKETLVSFEILPPLKGKGINALWEHLDPLMEFKPSFINVTYHRSESMFKKK
PDGTFEKVEVRKRPGTVGICAALMNRYQVDAVAHLICGGFNKQETEDALIDLHFLGVNNV
LVLRGDAPRNESSFEPEPGGHRYAIELEQQIINMNNAIYLEEDLKNAVKTSFCIGVAGYP
EKHFEAPNMQTDLAFLKAKVDAGAEYIVTQMFFDNQKYFAFTQACKDAGINVPIIPGLKP
ITTKKQLSIIPRTFHVDIPEELSTEIMKCKTDAEVEIVGQEWLLKQSKELKAAHVPVLHY
YTLGKPHVIANVVKDL
>A0A3L7U393|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MHIRDVLARDGMTASFEFFPPRTDAAWNEFVASLPEFEALQPSFVSVTYGAGGSTRDRTD
ALVTRLATDTTLAPVPHLTCVGHSTDEINQILQAYASRGVSNILALRGDAPRSQTAESAD
FRHAIDLVRAVKSFNEARRHPDQRGFGIGVAGFPEGHPETPNTLVQMDHLKAKVDAGADF
IITQLFFDNNAFFDWKARCSLAGITVPVIAGVMPVTTLTSLKRMAELAGGTRFPAPLLRA
IKRCEDDAESVANVGIHWATEQARDLIDRGVDGIHFYTLNRSDATRRIYRTLGLAGRVGS
AATGNQIR
>A0A5C7WC35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas alcaligenes|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMGVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GDVGVPTAPHLSCVGDSKDELRSLLSQYKNSGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGDHFHIEVAAYPEVHPQARSYEDDLQNFVRKCRAGANSAITQYFFSADCYFY
FVERVRKLGVDLPIVPGIMPITNYERLLRFSDSCGAEVPRWIRKKPEGHRD
>A0A2E5SM30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYREHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A4Q5R5C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIDHIREASGTLVSFEILPPLKGKTINSIYDHLDPLMAFKPSFINVTYHRSEHVFKKK
ADGSFEKVEVRKRPGTVGICAAIMHHYKVDAVPHLICGGFTKRETEDALIDLNFIGVDNV
LVLRGDAAKNETVFEPEPDGNRNALELLRQVNNLNNGIYLEDDIRDGFRTSFSIGVAGYP
EKHFEAPNMDTDLAYLKDKVDAGAEYIITQMFFDNKKYFDFVKRCRAIGIEVPIIPGLKP
LTSKKQLSVLPRTFHVDLPNDLITEVMKCKSDAEVELAGGEWLLQQSRELKKEGVPVLHY
YTLGKPKVICSVVQELF
>A0A3E0N6Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MNIGAAYGPGKFGLSFELFPPKTDAGETALFRHVDTLIEFEPSFITCTYGAGGSTRDKTL
SIISQVHERYQLPVASHLTCVGATADELRTYLQEAQSRGIGNIVALRGDPPQGETEFKPV
AGGFRFAVDLVEMIDAEFSELGIAVAGYPETHQEATSPAADLENLKRKVDAGGDVVITQL
FYDNADFFRFRDSCDALGIDAPLVPGLLPVISFKQIERIASLCGARLPDDFREALAACGD
DAAAQVDVGVEFASRQVQELLDAGVPGIHFYVLNRSEATARVLREVHRAS
>A0A521Y9J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquabacterium sp|TrEMBL
MSTSARLPISLEFFPPKTPEGAAKLAAARQELYALKPEFCSVTYGAGGTTQSGTLQTVQA
ILAEGVDAAPHFSCIGATEASVREQLAGFKAAGIRRIVALRGDLPSGYGSAMADPGTFRY
ASDLVAFIRRETGSHFTIEVAAYPEAHPQASNPQADLRAFVTKVQAGADSAITQYFFNAD
AYYRFVEEARRAGADLPIVPGIMPITNSAQLIRFSDACGAEIPRWIRQRLLGYGEDLASI
QAFGLDVVSDLCERLRAAGAPGLHFYTMNQVRATRAICERLGW
>A0A3D4D350|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MQGTTNIAEVLGQEKPTVSFEFFPPKSAAASERLFSTIHELKQLNPSFVSVTYGAGGSTR
ERTHKLVLRIMEETTIPAIPHLTCVNHSIEEIEGILSGYADAGVPAVLALRGDPPGEDIE
YNRNQDAFPYASDLVSFIQGFNQEAKTQQKGFGIGVAGFPEGHPDTKNRLKEMDYLRQKV
DAGADYICTQLFFSNYSFLDFRDRCRLAGIDIPIIAGIMPITTRSGMERMADLAAGVHFP
AQLQRMLQGANDDPAAFETAGSDYATIQCRELLSEGVDGLHFYTLNKSSATRQVATELNL
GR
>A0A3D1IQJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDILHEAAEAGRPAISCEFFPAKTPQGEQALVEKIVPRLKAVNPAFFSVTYGAGGS
TREKTLGIVDAIQQKHQVPTMAHLTCVGSTRADIGSVLDEAKQRGIDNILALRGDPPPGE
PFTKPEGGFEYSYELVEHIHTRNEFSIGVAGFPEGHIACTEGREVDWDRLKAKVDSGADF
VITQLFFDNADFYAFRDYLRERGMSQPIVAGIIPILSARQIQRFTELCGSKLTPEITARL
DELGDDDESVSIFGIEYATRQCADLIENGVEGLHFYTLNKSRATLVVAENLGLTQ
>A0A011U2D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. MRS-1|TrEMBL
MAHEPRVGAPAAAVTASPRVPFSFEIYPPRTPEQLPALYETIRVLAAAGPRFISVTFGAG
GSTTDRSLTVLTHILRETTVPPVAHVTCVGSSYAEATTVIRDFLDAGITRFLALRGDPPV
GIGEDDIVFGDLESAAQLVQLIGRVQAERSPYREREIPGVPGAVRVIDGDRVQIAVAAFP
NGHPRSRHRYEDIDALLAKQAAGATSALTQLFFHADEYLDFVERARAAGVVIPIVPGIMP
ITSPGRLRRVLELTGDARPDALAAALESAPDAAAQRAVGLAHAADLARSVVAGGADGIHL
YAFNNHDTVLGVLRAAELISEASP
>A0A2E4NYN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp|TrEMBL
METQKQFKRRFSFEFFPPKTDKGWEKLQGVRNTLAEVDPDFFSVTFGAGGSTRDRTVQTV
LDLHKRGVSTAPHLSCVGATRDSIAELLDVYRDNGINRIVALRGDMPSGMGAAGELRYAN
ELVKFIREYSGDTFNIEVAAYPEFHPQARTAEDDLKNFARKVEAGANSAITQYFFNADGY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCAKLLAAGAPGLHFYTLNQAEPSLSIWKNLGIGEREKIAF
>A0A6B2G887|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium|TrEMBL
MKVTEHIAKANGKTLFSFEIIPPKKGHNIQQLYDNIDPLMEFKPPFIDVTTSREEYIYIE
RNGLLDRKVTRMRPGTVGICASLRYKYNVDTIPHILCGGFSKEETEYVLVDCQYLGIDNL
MALRGDAMKHQRFFEPTKGGHEYAVDLVKQIGDLNKGIYLHDLMETPTKADFCIGVAGYP
EKHMESPSLSSDLKRLKEKVDAGANYVVTQMFFDNQKYFKFVKAAREMGITVPIIPGIKP
LAVSKHLQILPHVFSLDIPQELIDSVSHCKDDKAVRALGIEWAIHQTKELLKAKVPVIHY
YSMGKSDNIKSIAKQFF
>A0A0F5IS75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides goldsteinii DSM 19448 = WAL 12034|TrEMBL
MKVIDLINGSKTTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQNTDLYHEHATDLQEQVNNFNKGIAVDGSTFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVERCRAEGIDVPIIPGIKPV
VFKNQLTVLPKIFRSDIPEPFAAELRKCKNDDEVKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMATDSVYKVAKEVY
>A0A2J4RD57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella michiganensis|TrEMBL
YAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRAITQFFFDVES
YLRFRDRCVSAGIDVEIIPGILPVSNFRQAKKFADMTNVRIPTWMAKMFEGLDNDAETRQ
LVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A3C1AVJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHIADILAAQRPTLSFEFFPPKTAEASEALYQTIGELEAYKPSFVSVTYGAGGSTRELTH
DLVVRIKKTTTLDPVPHLTCVCHSEADIAAILERYAEAGVSNILALGGDPPKNLDGYDRK
KDAFQQAADLVRFIKKFNDSGAHPDKRGFGIGVAAFPEGHPTTPNRVLEMEHLKAKVDAG
ADYICTQLFFDNHDFLDFRDRCRLSGIHIPIIAGIMPITSASGMRRMAELAAGARYPAKL
LRAIQRCGGDEEAVQRVGVHYATEQCRDLLENGVDGIHFYTLNKSQATREIYASLGIRDS
AAVRPA
>A0A2M6UAE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium nitroreducens|TrEMBL
MTDLTIPARTNGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHATIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPVG
GIGTPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARAFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGIDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A2A5DUH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MTISEKYKQDKLICSIEIFPPKTEKGMKKLTQLLGEFDDYSPDFVSVTYGAGGSTRDTTL
QVVEEIVNNHTYDVMPHFTCVCHSKDEIRSIIKKYKDMGVFNILALRGDPPLNSDINLEN
DAFKYASELISFLKSENSFDIGCAGFPEGHTESVDLKTDQKYMVKKINKGVHFAITQFFF
ENHRFFDWRENLRNQSVDIPLIPGIWMPANETTTLKFSKMNNISVPDEVLNIYSKYESEE
SRLKASIEFTQKQVEELVANQIEGLHIYSFNQIESVKALAKFFNK
>A0A8G1Y0E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. p99-361|TrEMBL
MSLLKTALREHHFVCVMEFVPKASAERFAAMQAIMDRAQLCGWPMTVAIGDRVGSPLDMS
PLDALASFDRPVPALPHFSGKDRERHHLLAQLQRMEAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPLWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQAAPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMREMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGIHDLKQLLALEARLAYWQTHVHTLEQWAPA
WQASWQMPGLPAVTFHPPQANWRQGESRVDASFKEKARYHLMHGMHGLLFSRRNSLSKAF
GWAVRQPLWTTRLGAQVLHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGSALNRCEFGDRECIHSIKYRTAKAVGQTAVLRERLIPCIEEQTRHRSSWPQWFAPPSP
RRVSPQPAPRTQPES
>A0A847XYR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolinea sp|TrEMBL
MESSSLEKRGRLTRDELIKLRSPLLSDGAMGTMLHQRGINFDVCFDELNLLNPALVGDIH
RSYIESGSQIIQTNTFGANHFKLSRFGLADKVEEINTTAVDLARRVVLGSFKSILIAGDV
GPLGVRLAPYGRVKPEEARAAFREQISALLKAGVDLILIETMTDLLEARAAVKVARDLDD
SIPIVASMTYTRDDRTLLGDAPAKVARSLLAEGADMVGVNCSGGPEQILRILRQMRNAVP
DSVFSVMPNAGWPEQVAGRIMYPAAPEYFGEYALSFYQNGARIIGGCCGTTPEHIAAMHK
ALSEAPLLEPAEAAQTVDAEAESQLQSETFVPTELARKISTGKFVTAVEMDPPRGLATQK
LLAAASLLSEAGADVINVADSPMARMRMSPWAVCNLIQQRIGIETVLHFPTRGRNLIRVQ
GDLLAAHALDVRNVFVIMGDPTSIGDYPDAMDNYDLVPSGLIKLIKQGFNAGMDHSGADI
GQPTSFFVGCALNLNPVSPKDEIKNLSRKINAGADFALTQPVFSPEAARSFLKTAKEELG
DLSLPILAGILPLANSRHASFLDQEVPGITIPASVLERMQKAGDNGPDEGVRIAVELVEE
LRPNIHGIYLMPAFNRFDLAAGVIEDIRD
>A0A7W7TVU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces nymphaeiformis|TrEMBL
MALGTASVRSDRARTVREILASGDTSYSFEFYAPRTEKGEQVLWNAMRRVEAVGPSFVSV
TYGAGGTTRGGTVKATQKIASDSTLTPVAHLTAVDHSVAELRNILGQYADAGIRNMLALR
GDPAGDPLGEWIEHPEGVKYAAELVQLIKESGDFCVGVAAFPEMHPRSLDWDTDIRHFVN
KCRAGADYAITQMFFDPENYLRFRDSVEKAGCETPIIPEVMPVVNVKTLDRLPQLSNAAF
PADVKDRILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHEQS
>A0A8G1Y3K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. p99-361|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVQVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRTETGDHFHLEVAAYPEMHPQARNFEADLGNFVQKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLALWNNLKLPR
>A0A0M0K4T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chrysochromulina tobinii|TrEMBL
MIPTGTCVYLPALPADPPDAVEGALRLLRRENAGLLAVPHIPATRVASTAALERQLGAWQ
RASGDGVREVLIVRGDLNAHHGEVGATAGAPSRGLFGRSLDLLETGVLQRAGIHAVSLCG
HPEGVGHLSAAGACEALVAKLQWAEAASVEARIVTQFCFSARATIAYAEQLRAAGVTAPL
SVGVVGPCKAEIRTRMAERCGVTPPAGGESDHPDGALLNEHDWPSEYVRALAQWQRDGLA
GASGHGVQALHLYPFGGLGSTLRWVEERLPGLMLPAQ
>B7RVE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine gamma proteobacterium HTCC2148|TrEMBL
MSRLANRISAGHFVVTGELTPPKGTDISGLKARAELLADHIDAFNVTDSHASKMSLSPMA
AAHELTVLGVEPILQMTIRDRNRIALQSDMLGAWLLGVKNLVCMGGDPPHLGDHPEAKPV
FDISTEDLIQAAGNLNNGKDMMDNLLSGSTGFHIGAVVNPGAEDLDKEIARLESKVAAGA
KFFQTQAIFDADRFAGFMERVSHLDIAILAGIMPIKSVKMAAFMNEKIPGIDVPDHVIDR
IDGAADTVKESTAVAAEIIKEIKPICQGIHVMALGWEEHIPGVLQLAGVTREE
>A0A3D3D581|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MSTTTAPLPISFEFFPPKTPEGAEKLRGVRQQLYARAPQFCSVTYGAGGSTQEGTFAAVR
EILAEGVDAASHFSCIGATRDSVRAQLAQLKAMGVKRLVALRGDLPSGYGIGGEFHYASD
LVAFIRAETGKDFHIEVAAYPEVHPQARSAEADLQAFAAKVRAGADSAITQYFFNADAYQ
RFVQDARRLGLDVPVVPGIMPITGASQLLRFSDACGAEIPRWIRLRLQGYGDDVASIRAF
GLDVVTQLCEQLVRAGAPGLHFYTMNQSAATLAICERLKL
>A0A0N1DMH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium acidisoli|TrEMBL
MMIAPQSESREKTPLADLLSHYSIEVTSRDLPSLQSMTATLPPGSEVFVAHLPNEDIGLL
VRAAAGLRDAGFVPVPHIVARNIRNRPELDTMLARLSEEAGVRRALVLGGDRDDAAGTFG
SALDLIETGLFQTYGIGRIAIACYPEGHPRIAGAVLDTALTAKVDAAARAGLDLLLVSQF
LFDQKPLLSFAQRLRERGLTVPLRVGIAGPASRTKLLKYALRCGVGASLRALRERSEIAR
NVLSGETPEELLIDIAAAQAAEPDLGISGVHFFTFGDPAQSIRWAEQQQPSD
>A0A6N7GRA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MKTVALAMTDQEERADAIRTISGFVHGYSIEATRPSADDIAGLGGIVPKGTSVYVSAVPT
QREDEAVEHASRLRRAGFEPVPHIAVRAFASANEIDRFLARLAADAGVRQVLVIAGDRDP
PAGSLRSALDVIDSGLLQRHGVLEAGIAGYPEGHPRIPGHELDRALADKIATAEATGLRL
HIVTQFCFDADAIIGWIRRLRDFGFDVPVRIGLAGPTSLPTLMRYASRCGVPASVHGLAR
HAGLMRQLFAMSAPDALVRALAAERERLGDVQAHFFSFGGLARTARWASAVELGHIALEP
GQGFRVEPAG
>B1ILP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum (strain Okra / Type B1)|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKNIIGE
YNYAFELIEKIKANNNFGVSGACYPEGHIECESLKQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQQKNINVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A7C1C230|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MEERVIEHISKAKSTLFSFELLPPLKGQDFTSTANAIDLLMEFSPAFINITYHQEEVVYE
NLPNGFMKKKTVRKRPGTVGIAAAIKYRYGVNVVPHIICGGFTKEETENALIDLQFLGIN
DVLAVRGDPQVGMKKFIPEPEGNQHALELVDQINKLNKGIYLDEELLNTRSMNFCIGVAG
YPEKHAESP
>A0A2G6GXK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MIPFKDYIAEKLVLLDGAMGSLIYEKGVFIDKCYDELNLSKPELIRSIHEDYVKAGAMVI
ETNTYGANRFKLKSHNLLDRLAEINTTGISLARKAAGDEVYVAASMGPSGMGIEPWGDLS
LDEAEEGFYEQAGYLHDAGADLFILETFQDIREMERAIRAIRRLSDRAIVAMMTVTEEGK
TRYGTDLHDLSRRLDASEADVIGLNCTVGPKPMLDFVEQIRSQSDKPVCIMPNAGRPQYA
DGRMIYMSTPEYFSVYTKRLIDKGVRMLGGCCGTTPEHISKMANALAMKQTRIQHSIETR
PRAERDEPLLEPVAMASKSRLAARLSKDEQVVLVEMVPPRSTDVSKSLDGARMLKEAGVD
AINIPDGPRASARMTGLALAVILERELGIETVLHYTCRDRNLLGMQSDLLGATALGIRNI
LAITGDPPMIGDYPQATAVFDIDAIGLVHLIDNLNHGIDIGEKRIGDPTAFLTGVGVDPN
SVNAGNEIHRLQLKKEAGAEFVITQPVFDIPSLEAFLEKCDLSGLRLIAGIWPLVSLRNA
EFMKNEVPGVYVPDEVIAQIARYADRDDQLKAGVELAREMVERVKPFASGIQVSAPFGRY
GLAVEVAGALLQGA
>A0A521W9C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
GTVLDLYEYPDLPHEIQNIKNPDIIERIHREYIEAGSEIIETNTFSANRLRLSQFHLQDR
LQEINTAGVEIARRAANDNVYVAGAVGPTGMLLEPIGKIKKQQARDAFKEQIEILVNAGV
DLIMLETFVSVQELDEALTIAKELTDLPIIAQKAFAEDGAILNGSYPIEVIEHLIELGAD
VVGANCTVGPQRMFSIIRNVHKEGVILAAQPAAGIPTLLNGRSIYHTTPEYLAAYAKELV
ESGVTLIGACCGSTPAHIRAIADTVRGMKVGKPAQKIEIKTSGQRQVEPEPRYYVETARW
SKFGRNIGKKFLTTVELDIPRGVDMTSVLEGAQYCFERKVDAVNITEGARARLRMSSIAL
STIVQQRVGIETMCHRASRDHNLIGLQAELLGAHALGLRNILCVTGDPAGIGDYPHATSV
FDVDSVGLIRAVSSMNRGTDIMGNPIGQPTWFTIACAANPCADDMDAEIEKLERKVEAGA
HIAFTQPLFEMRTLETFLQRIKHLKLPIMLGVIPLRSYKHSEFLHHEVPGMRIPDNIRET
MRTAGNNASKVGIRLSQEFMKEAKSFVAGIYMMPPFQKYHVVDELLSVI
>A0A402BH86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyobacter alpinus|TrEMBL
MQTHYPFLERLRNGPLLCDGGMGTELYARGISYERCFEQLNLTNPELIKSIHLDYVAAGA
QIIETNTFGANRYRLAEHGLDNQVVEINRAGAKIAREVRELSEQPILLAGNIGPLGSPLA
PIGTIQPADARAAFIEQTEALLQSGVDLIIIETMSDLAEMREALMAVRSITDLPVVALMT
FGEDGTIVSGEDAQVVAETLRDLGANVFGVNCALGPASMFDVAKRMCSYNSDDFFVAVQP
NAGLPRRVGNRFIYVSTPEYFAEYTRRFLSIGIRMIGGCCGTTPRHIAAMHEVITELAPT
ISPEMEKPSSAPTLEAFRERIQESAAQNAESEPAPTQLAALLQERKFVISIEMSPPRSVK
FTRFLQNATLIRDSGADTINITDNAMARVRMNNVAAARLIQQNVGIETIVHFTPRDRNLM
AVQSDVIGAHATEIRNILAVTGDPPSHGDFPNSTGIWDVDSIGLISILSNLNKGLDGNRR
KLAAASSFFIGCAANPAASDLDIEIERLHQKIEGGAQYIMTQPVFDAGTFLYYINKYKDQ
YGEIPIPILIGLQPLHSYQQAEKFHNEVPGIVIPEEIRQRLQQAGEGGGAVGLEIIKELF
DKLKAEVQGTYIMPLDRFELIEDLIPYIRQRTAQ
>A0A0R3IBM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides sp. H001|TrEMBL
MTTNPLDHDASVAELQDPGSIADRLAGVQPGDVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDLE
RDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEEQLLRAAGDGPEEDRDEVRKVGVEVATSMAARLVAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A3M1YT20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTTYFEKANGQTLISFEILPPLKGGSMQAIFEVLDPLMEFRPPFIDVTYHREEYVYKQ
RASGYFEKIAIRKRPGTVGICASIMHRYGVDAVPHLICGGFSKEETENALIDLNYLNINN
VLALRGDARKFDGKFIPEKDGHHYAIDLVKQIADMNQGRYLDDNIENGEKTDFCIGIAGY
PEKHFEAPNMASDLYYTKAKVDAGAQYIVTQMFFDNQKYFDYVEACRKTGIEVPIVAGIK
PLTKKYQLSALPRLFHIDLPQDLVNEFLKAKTPEARQEVGIEWSIMQCKELKARGVPCLH
FYTMGDVDTIRRIAEQVF
>A0A4Q3FLN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MNAFRPSRHGSRRPRVSFEFFPPKSEEMEVALWESVRRLEPVGPSFVSVTYGAGGSTRER
THATVKRMIEETGLKPAAHLTCVSASRSEVDEVIRSYWDAGVRHVVALRGDPAGGLGTTY
EPHPQGYDQTSDLVAGLKRIGDFEVTVSAYPEKHPEAASLDDDIDALQKKVDAGATRAIT
QFFFDNDVYFRYLDKVRARGIEIPILPGIVPVENFKQTANFARKTGASVPQWLADRFEGL
EEDVATRRLVAAAVCAEQVLDLIDRGATDLHFYTMNKADLVYAICHLVGLKPEKAAAQAV
AAE
>A0A537I2Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKIIDHINKAQGTLVSFEVLPPLKGKGIDALYKHLDPLMEFKPAYINVTYHRSEHVFKKR
TDGSFEKVVVRKRPGTEAICASIMNRYNVDTVPHLICGGFSKQDTEDALLTLSYLGIDNV
LVLRGDAAKNETAFEPEPGGHKYASDLLKQVVNLNHGIYLEEELKGTNGTKFCIGVAGYP
EKHFEAANMEADIKYLKAKVDTGADYIVTQMFFDNKKFFSFVDNCRAAGITVPIIPGLKP
LTSKKQLAIIPRTFYVDLPTDLLNAIIQCKTDEDCEKVGEEWLLAQSKELKAAGVPVLHY
YTLGKPQVVANVVKQL
>A0A495VNG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprobacter fastidiosus NSB1|TrEMBL
MSMKVIDLIKNSPTTAFSFEVLPPLKGNSIEKVFNTIDTLREFDPKYINITTHRSEFLYK
DMEGGLYKRVTVRTRPGTVAVAAAIQNKYQIPAVPHIICSGFTQSETEYALIDLSFLGIC
DLLILRGDKAKHENRFIPTPEGHAHAIDLQAQVNRFNEGYFLDGSKMSLINTPFSYGVAG
YPEKHDEAPNPDSDLFWLKEKVKAGAEYIVTQMFFDNEKYFSFVDRCKSEGIDVPIIPGI
KPINFRNQLTVLPKVFHVDLPEALASELRKCKTDEEAKEVGVEWCILQAKELKEKGVPSI
HFYSMMATESVKRVARQVY
>A0A249LGA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Planktophila limnetica|TrEMBL
MSKLRDLLTQTKDVVYTAEFPVIDGGGMDQVKKNVERLAPWFVAVNATDNTAAHAHASNV
SVAIAMKQHGLEPIMQIVCRDKNRLAIQADMAGANLHGIENIALLTGDDVTAGDEPETRR
VFDLDGPQAINVASILNAGTYLSGRKLNPAPNFFICSVENPFAPPHDYRIERALKKHRAG
AQMIQLQIGYHPDRLEKFCAGVAATVPDLAIIPSVVLIKSAKPLSFMNDKVPGISVPQDV
IDRVAQSSDQAEAAYQLALEQAQHALTLPGVRGLHITDFRHDDTLERLMRDLGRTPNQYT
>A0A4Q3GGK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSTDYTDRPSRMRPDERPKFQVSFEFFPPKTDVMEERFWESIHKLAPLHPRFVSVTYGAG
GSTRERTLRMVSRVKAETGVDAAAHLTCVGATRDEVDAVVRGYQEAGISRIVALRGDPAE
GIGKPFTPHPDGYRNAADLVAGIREIGEFDISVAAYPEKHPQSPSWQADIDNLKRKLDAG
ATRAITQMFFDNDDYFRFVERARAAGISAPIVPGIQPIHSFKQISGFAARCGASIPGWVA
ERFEGLDEDPETHALVASAVAAEQVLELVDNGITEFHFYTLNRSNLVLALARLLGARPD
>A0A2T5V523|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Breoghania corrubedonensis|TrEMBL
MIEHANERHARQTGENDVHVSFEFFPPKSEKMEESLWQSITKLAPIAPLFVSVTYGAGGS
TRERTHNTVARILKETGLKPAAHLTCVDATRDEVDEVIRSYWELGVRNIVALRGDPAAGI
GTAYQPHPDGYVNAADLVAGIRRIADFDVSVSAYPERHPESADWGVELDNLKRKVDAGAA
RAITQFFFDNDMFESYLERVRAAGIDIPIIPGIVPIHSFKQVASFSAKTGTSVPDWLAHR
FEGLDEDPETRKLVAATVAAEQVMDLVDRGVTDFHFYTMNKADLVFAICHLLGLRPKTPE
QEAA
>A0A351GJ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKLTEYIQPNKTLFSFEVLPPLKGKSIDSLYNAIDPLMEFKPSFVDVTYHREEYIERPRK
DGGYDKISTKKRPGTVAICAAIMNKYQVEAVPHLICGGFSKDETENALIDLAFLGIENVL
ALRGDNLKNERNFIPEKNGNGNSLDLIRQIGDMNNGVYQDQELENATETNFCIGAAGYPE
KHIDAANMQSDLKFLKRKVDAGAEFITT
>A0A4R3Y0I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurirhabdus autotrophica|TrEMBL
MIMTSKNKGHPRTFSFEFFPPKTPEGREKLRATRQQLAQLKPKFFSVTFGAGGSTRDHTL
DTVVEIQSEGFDAAPHLSCIGSTQDNIRAILNEYKSHGIRHIVALRGDLPSGMADPGAFR
YANELIEFIRAETGDYFQLEVAAYPEYHPQARSAKDDLLNFKRKVEAGANAAITQYFFNA
DAYFNFVDECTAMGIDIPIVPGIMPITNYVQLARFSDACGSEIPRWIRKKLEGYGDDLPS
IRAFGLDVITNLCDRLLQNGASGLHFYTLNQAGPTSTVWQRLGL
>A0A2I6S3Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aromatoleum pumilum|TrEMBL
MQTTELSIEFFPPQTPVGAEKLRVVQTRLAEALDPAFFSVTYGAGGSTRERTFNTVREIA
ATGAEAAPHLSCVGSSRAELRAILDEYMEAGIRRIVALRGDLPSGAGAGGELRYANELVE
FIRAETGNRFLIEVAAYPEWHPQARTPRDDLTNFKRKVDAGATSAITQYFYNLDAYTHFV
DEVRALGVTIPIVPGIMPITSFSKLARFSDACGAEIPRWMRRKFEAFGDDADSIRAFGLD
VVTELCERLLAAGAPGLHFYSMNQADATIEICRRLGLAKG
>A0A2A5FYZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MMNVKANERTLPVSIEASPTQILKNEAIGELFPSGSWVYLTDVGTAPLETMVAAAKKLKS
HGFEAVPHIPARRITSNVDLEHRISALVNEAGVSNVLVIAGEAEHQQGPYASTMDILQSD
VLSANGIARIGVAGHPEGNTSISDEMILSSLRAKSDFAQNTDAQMRIVTQFGFDTASFLS
WADSLPGLGIDLPVHLGMAGPAKMTTLIKYAAICGVGPSLRFLRKRMSALSALALGYDPE
PALADLEAHLAANPASLIQAAHVFPFGGLKKSANWLDERGSWNIKKSLYLDANVI
>A0A8H6G5Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Letharia columbiana|TrEMBL
MHIKDKLAEAERSRKPVFSFEFFPPKTALGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRS
DLTCEMVNTAQTIYGLETCMHLTCTDMEKQKVDDALKSAYSAGCSNILALRGDPPRENEK
WQAVEGGFRYARDLVEYIKARYGDHFDIGVAGYPEGCDDQQDQEILLEHLKEKVDAGGTF
IVTQMFYDVDIFLSWVEKVRARGISVPIVPGIMPIQTHAAFLRRAAWSKCHIPQKWADAL
EPIKNDDAQVREVGKGLVAEMCRKIIDAGIMQLHFYTMNLAQATRMVLEELDLVPKDGTP
NTRILPWRQSLGLNRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDARSPAFGELDA
YDIGLKGTNEQNVKLWGKPESVRDVANIFIRFLEGNLQSLPWSEAPITSEAEAIRPELIN
LNRRGLLTITSQPSVNGVKSTHPVHGWGPKGGYVYQKTYVELLISPQLIPELIARIERSS
TMTYYAVTKGGDLSTNAPSEGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAYHLGADW
AKCYAASSPSRQLIDKIMDTWYLINIVDNDFHQTHAIFSLFEGLEVEDLDKPSVNGHQSN
DHCPTANGAPIEVHN
>A0A6N0JU95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter denitrificans|TrEMBL
MSDSISPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGSSRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSGDLDHFVRKVRAGADAAITQYFFNADAYF
DFVDRAQAKGVAVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPMAVWKELSLQA
>A0A853IG20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endozoicomonas sp. SM1973|TrEMBL
MNTQSSLPISFEFFPAKTEAGAEKLLNTAKKLAASNPEFFSVTYGAAGSTRDRTAGTVFD
IKSLTNISTAPHLSCIGANKSEIAELLALYQKHDIKRIVTLRGDLPSGMGLASGELRYAN
ELVEFIREQSGDQFYLEVAAYPEIHPQAPNAEKDLENFKRKVDAGANSAITQYFFNADSY
FYFIERCQKLNIEIPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDATSIKQ
FGEHVITQLCEKLISQGVPGIHFYTLNQAEPSLAIVDNLGLGK
>A0A6P0VU97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symploca sp. SIO1A3|TrEMBL
MTKPTHNSFRAAAQSGEFLITAEIAPPKGGNPDHMVKMAQALKGRVHAVNITDGSRAVMR
MSPLAASVILLQYGIEPICQVACRDRNRIGLQGDLLGAQALGIHNILALTGDPVKAGDHP
DAKSVFDLESVRLLKIITQLNQGLAANDKPLTDGATDLFAGAAVDPQLKSWSGLQSRFER
KIEAGAQFFQSQLITDFERLEKFMDKIAAGTDKPILAGIFLLKSAKNAQFINKYVPGVNI
PQAIIEQLANAANPLQEGIKIAAEQVKTAGQICHGVHLMAVKREDLIPQILDLAGIVPLN
EAN
>A0A7X3LQY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stappia sp. GBMRC 2046|TrEMBL
MTLSHSIRRFQLGEKSDISVSFEFFPPKNDKMEASLWSAIERLEPLAPNFVSVTYGAGGS
TRERTHRTVARLVNETGLHPAAHLTCVGASRGEIDAVVRDYRDLGVKHIVALRGDPLEGI
GAIYKPREDGYAYACDLVEGIRRIGDFEISVAAYPERHPESPDWSFEIDNLKRKVDAGAT
RVITQYFFDNDQFEEFLNRVRAAGINVPVVPGILPITNFEQTVVFSAKCGTSIPDWLTRR
FKGLETDPETRKLVSSAVVGEQVLDLVDRGVNEFHFYTMNRAELTFAICHMLGVRPVAPE
KQAA
>A0A7X0GEA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. AZCC_0090|TrEMBL
MFPTRIEIIPSDGIVEKVQAAVPVSTTLTVTCLPHHGITRTMEASIKLSLLGYNVIPHLS
ARGLEDRAQLSGSLRSCVAAGITEVFAIGGDGPRGAGPYESCLHLLEDIAEYSGGRISAG
IAGYPEGHPSVSGLDLLDALLAKQPLATHVVTQMCFSAPKILDYAALLRREGVELPVWAG
VAGVVPRTKLLALATQIGVGTSLKFLSNRGTLARKLLGVDKYSPEGLVSELKAHPDSVTG
IHLYSFNRLDMPSWERSNLPDPEASEAASA
>A0A7Y9MDX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia sp. AK011|TrEMBL
MTTSPVRAITRADATFSFELYPPRSSEAETALYASIAELVAVSPEFISVTYGASGSTRGL
SLSVLTHMLRNSSVEPMAHLTCVGSSYAEASQLIREFLDAGVTSFLALRGDPPAGATEDD
DFLGDLGSAGELVQLIHRVQKEREPFRFSDVPGFPGAKRVTHGEKVTIAVAAFPNGHPRS
RSVDQDLDTLLAKEAAGANLAITQLFFHADEYLGFVERARAAGVTMRILPGIMPVLSPRR
LERILELTGEATPRSLERELAAADSQGAQAAVGIRHAIELGDQLLEGGAPGLHLYTFNQH
QAPLAVLRGVGLVGDPGSPTTPPREKELA
>A0A4S3L4X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus kamchatkensis|TrEMBL
MGLLDDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIESGAEVIQTN
TYGANYVKLARYGLQDDVKKINEAAVGLAKRAAKGRAYVLGTIGGLRSTNKSAISLEEVK
RTFREQLYVLLNEGVDGLLLETYYDFEELQTVLSIARKETTLPIIAHVTLHDIGVLQHGM
PLAEALTELERLGADVVGLNCHLGPYHMLRSLEEVPIPTRAFLSVYPNASLPQYRDGRFI
YETSEQYFEETARAFREQGVRLIGGCCGTTPKHIAAIARALSDRTPVYKKEVKQRHPIVV
QEEKQTTAPSLADIARTRRSIIVELDPPKKLGLTTFLEGAKALKEANIDALTLADNSLAT
PRISNVAVGTIVKQQLGMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRI
EKKIECGAHYFLTQPLYSEKQIEDVYEATKHLPTPIYIGIMPLTSARNADFLHHEVPGIT
LSDDIRNRMAMCANDRVQSTKEGLAIAKALIDAAFDLFQGIYLITPFLRYDMTVELVRYI
HEKERLAKERTVYYG
>A0A7X0GA11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. AZCC_0090|TrEMBL
MSPPSLIGTHPNLTGAAPVALSYELFPPRSPAAAESLWTTIGELEATDPDFVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAEIIGELLDNGVRGILALRGDLPKD
SGQPVSGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSVEHDVEVLL
AKQRSGADFAITQVFFHTEQYADLISRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAPELIERLAAADTDAERRKIGVRATVDLANAALQAGAPGIHLYTFNEHTCALDVLDKLA
LPRPARPASRLHAIARRQELVS
>A0A4Z0QFX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter metallicola|TrEMBL
MKVTEHLSRAAGKTLFSFEVLPPKKGENIHTLFSNIEPLLEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGHFKPEPDGHAYACDLIGQVSNLNKGEYLDEEQDDTWATNFCIGTAGY
PEKHFEAPNYGADLRYLKHKVDRGAEYIVTQMFFDNEQYFNFEKRCREAGITVPIIPGLK
PLTTKSQLTMLPRSFYLNIPEELAEAVHLAPDNEAARQIGIEWCINQSKELMAHGVPCLH
YYSMGKSESIRRVAAALF
>A3LW82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)|TrEMBL
MATIKQKIAALGPDEKFISFEFFPPKTDSGFRNLLARLNRMSALNPLFITVTWGAGGSTS
EKSLDLAATCQNDLGLTTILHLTCTNTNKEIIDEALKRAKESGIRNILALRGDPPRAEEY
WTPNCDFNSAVDLVRYIKENYGDYFCIGVAGYPEGHVDGSDGADQNPQKDIPYLIEKVEA
GADFIITQLFYDVDKFIAYDSLLKSYAQLKDVTLIPGLMPITTYKVFTRASKLSHASIPK
TISRKLEASVGNDDAIKSLGVEIVSDIINTITSKTSIKGFHFYTLNLEKAVASILKNSTV
MQTIMERASSTEESINDDAIASSDEEEGKRKSSIINENSLSDKSLALSAQRSLVGKALLK
DKKVLVDISTGKGALGKEAIWDDFPNGRFGDSNSPAYGEIDGYGPSLKVASPEEAIAKWG
SPESVGDIAKVFMGYLSGKIDILPWTDSSLSAETTLIQEELFDLNDRGWFSLASQPAVNG
CKSTDRIFGWGPKNGIVYQKAFVEIFVPKEQWESELKSSLKPHFEEKTITYYVGDAEGNI
ESNLFVGPDAHNSKNAITWGVFPSKEVLQPTIIDYESFKAWNEEAFLLWIEWARCYKKNT
KTFQLLNSIYSNYVLVSLIHHDFTDEAGLWTLLLQ
>A0A554WLQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidimonas sediminis|TrEMBL
MALPLSFEFFPPKTPEGAAKLRAARQRLYAARPQFCSVTYGAGGSTQEGTLATVAEIQAE
GMDAAAHFSCIGATRERVRAQLAELQRMGVKRLVALRGDLPSGYGLGGEFTYARDLVAFI
RAEFGAAFHIEVAAYPEMHPQARSPQADLQAFAEKVRAGADGAITQYFFNTDAYFRFVDD
AHVLGVDVPIVPGIMPITNASQLMRFSDACGAEIPRWIRLRLQGYGDDVASIRAFGLDVV
TDLCDQLRTAGVPGLHFYTMNQAEPTLAILQRLGMIEAG
>Q1GX61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256)|TrEMBL
MTANLDALAEARRAAASPLFANLDGDVGVSFEFFPPKSEKMEAQLWDTFRTLEPLAPSFV
SVTYGAGGSTRERTHATVARIAAESRVPPAAHLTCVEASRAEIDEVARAYWDAGVRHIVA
LRGDVPGGGPYRAHPDGYANAVELVAGLKAIAPFDISVAAYPEVHPDADCPQSDLDNLKR
KLDAGANRAITQFFFSPDSFLRFRDTAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMVSLFDGLDDHPAARQLVAATVAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVSTLKDRAA
>A0A1V2PTR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinosynnema sp. ALI-1.44|TrEMBL
MTSVLERINVAHATFSVEFMPPRDDADEQILWRSIRELEGLDPAFVSVTYGAGGSRRDRT
IRTTGRVARETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVHNVLALRGDPPGNPMGEWV
KHPQGLSYAEDLVRLVRELGDFCVGVAAFPYGHPRCADIDTDADRLVRKFRAGADFAVGQ
LCYSAEDFLRLRDRVAAKGGDAPILPGVMPLTTPKMLSKTVELSGAPVPPHIASRLEPLA
DDPKAFRAEGIDVVTEMCQQLLAEGVNVLHFYTFNRAKATKEVLGRLNLVPSRTA
>A0A4R7T5Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2575|TrEMBL
MANGLPSKLPGATPTIRELLATGQRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSKDELRSVIGAYAGSGVRNVLALR
GDPPGGPNQPWVAHPEGMNHAIELVELVRELGDFCVGVAAFPDKHPEASSLEADAQVLAA
KAKAGADYAITQMFFGAGDYFRLVDRAAALGCDIPILPGIMPVTNIKQIHRMAELTGMAL
PTAVTDRLHAVEDDPAAVREVGIEIASELCDELLAGGAPGIHFITLNRSTATRQVYRNLQ
SAPV
>A0A1Y4U1L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp. An118|TrEMBL
MKIKDILRGEGIHISFEVFPPKTEDSYDAVLEAAGEIASLQPAFMSVTYGAGGGTSRNTV
RIATRIEEDFQVPSLAHLTCVSSTREEVRQVIASLRERGIENILALRGDIPEDVTFPLPH
HYRYASELIEDIRREGDFCIGAACYPEGHVEAATQKEDILHLKHKVDCGVDFLTTQMFFD
NSILYSFLYRIREAGITVPVLPGIMPVTNAKQMKRICALSGTVLPQRFRAILDLFGDHPA
AMEQAGIAYAVDQIIDLIANGIQDIHIYSMNRPRTARAIMDGLSEVIKA
>A0A535L7M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
ILSLTGDPLHVGDYPNTTGVWDLDSVGLIQVLRRMNEGHDAASSSIGAQASFHIGMALNL
NMTEQETEQEIDKYRRKIEAGAHFIMTQPIYELARLERFLARAGKPPIPMLLGCIPLHSS
RHAEFLHNEVPGITIPDDVRSRMRAAGDQGHEEGLKLAQELLTSARSMIEGVYLMPSYGR
YDVVSKLTKMLQMQPTP
>A0A7V3VAU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MAELFKIRQTPIISFEIFPPRTPEGEKALFEHGLPKMVELRPGYFSVTYGAGGSTQAKTV
ELVQRLAQDHNANVVAHLTCIEATKSKITELLQTYQRIGCVNILALRGDPPRDAQKKIFK
SDFKYAIDLVRFIKATGDFCVGVAGFPEGHPECQGGKHINWQHLIQKIEAGAEFVITQLF
FDNRDYFEFTEFLSRQGIKIPIIPGIIPITSAKQIFRFTELCGARIPDKIKDALERFGEK
DDEVTRFGTEYAISQCSELINAGAPGLHFYTLNRVEPTRTILQTLGFV
>A0A6L7UY58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTRISQLLDAGPTLSFEFSAPRDEDGAERLRQTLGQLSLHRPHFMSVTYGAGGATRGPTR
DWVRAIRADFGVEAMPHLTCVAHTRDEIAEIIKHYQSDGITNILALRGDQPQTASPLPPS
GGEQPQPTFPLPPSGGDRRAASPRAKREGGVGGVGWGLVGGGGGGGGGG
>A0A6I1K4E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MIQFIRDIHAAKKAAGQPVISFEFFPPKTDEGDKNLLERHIPELMKLKPDFCSVTYGAGG
STREKTIGIVDRIQREHGLTAMMHLTCVNATKAELTTVIAEARARGIKNILALRGDPPGG
GEFTATPGGFEYSHQLVSHLRELGGFSIGTAGFPEGHIACKEGRQVDWDRLKAKIDCGAD
FVVTQLFFDNADFYAFRDYLTKQGVTVPLVPGILPASSGSQVKRFTALCGAQLPAPFLAG
LDKCGTDDAAATAFGIEYASAQCADLLKNGVEGIHFYTLNKAHATTRILQNLRLA
>A0A7C2TH26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNRADFLSLLDSSSLPFLGDGAMGTMLNAGGVGFDQCFDNLNLANPALVAEVHRAYIEAG
AQIIQTNTFGANRYKLAAHGLEGRLAEINHAGVELARRVALASYKEVLVAGDIGPLGVRL
APFGRVQAEQARQAFADQMVALVEAGADLLIIETFSDLAEIQEAVRAAHQVCDLPVVASL
TFTRDDRTLLGDTPAQVAQTLYAAGVEVSGINCSGGPAQAYRILNQMRQAAPQARFSVMP
NAGWPEQVGDRIMYPANPDYFGEYARAFCQAGASLVGGCCGTTPRHIAAMRAALDRVPQG
CAPENDEMLTAVETEARSAAAEQLSGLAHKLAEGKFVVSVEMDPPRGLSTHKLLAGASLL
AETGADVINVADSPMARMRMSPWAVCDLIQRTVGVDTTLHFPTRGRSLLRVQGDLLATHA
LGIRNVFVVMGDPTAIGDYPDAMDDYDLVPSGLIRLIKENFNAGVDQAGIEIGQPTSFFV
GCALNLTPQDLERELKGLRRKLSAGADFILTQPVYQPELAAAFIQRYRDRYGELEVPVLV
GVLPLYGPRHATFLHNEVPGISIPEAYYHRLQGAGELAPQEGVRIALELIEQMKPWASGI
YLMPAFNRYDLCAEIVESCR
>A0A6L7RWQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MASDDVPTPASSGISALFSDGFKVAIEVETSRGLAMEAGAQHSLELAQAAAEGGRVDAVC
FTDNPGGNPHITPETLGRELLDRDIEVVINLSCKDYNRNSLEGRLWSLSSLGFDNVLCLS
GDYPVDGLSGQAQPVFDTDSVGLLEMIRRMNEGLRVTLPGRRSSETELGRTNFNPGAAVN
PFKLYEGEYLTQLYKMDMKIRTGAQWFVSQIGYDARKHHELIRYLDLKHGAQKPPVLGSI
YVLSAPAARFFGRWGIPGVAVNSDLVEVANGAAKSKDRGRSFFNELAAKQIAVLRGTGYN
GVYLSGRLTYKRIEQILDIADGIKGDDWKKAAAEIGYAQPDEFYLFEPGDSTNTASDEVN
RDYEQRRSRKASVFRRAIHPDLPYRIGRFGKHFVFDHNAPAFKASAAIYRQIEKSKVATK
AAHAAEQMMKVPLYGCRDCGDCSLPDIGELCPESQCVKNQRNGPCGGTRAGKCEILDKDC
IYLRAYNTLKLYGEEESMLQHPVVFKDSSLQGTASWANTFAKRDHYGANS
>A0A6L3EWF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPLFSPPRYQPPFSPVQRESVSMRVFTAVEKAIKGALFGCRMCGNCILQETAFVCSMTCP
KGLRNGLCGGATPEQCEVDPSRPCTWYKIYERAEKMDRLDKLLEINAPIDGAQAGRETWL
HMIDFWRKHEESPRLIELVTDREKFTKEWERVFYDLRQPSWWQGDAEYHPPTYVEPISLL
EANLRTGDFVTTAEIAPPLGASGNIILKKAGWLKGYVAAANFTDNASASARMNSMASSRI
CLDAGLEPVMQLQARDRSRVIIEADVMGAAGLGIRNILCLSGDHHRFGPTPMVKPDQFDM
DAVQVLWMLRRMRDEGIYLDGRPIKRRPAWFLGAAGSPFGAPPKYEAIRAEKKINAGAQF
IQTQPVFDYDGFVDWLEALDKRNLLDKAYILPGLIPLKSKNAAHFMANDVPGVSIPPEIV
SRMDNAGGKEGQQEEGIAIALEMIEKLKNTPGVNGMHVMAVHWEAIVPRLLESADVPKPK
FLEWPLLVKANGVEKPMVKSPLT
>A0A7C6DML2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
LAAARLIQEATGLEVIIHFTTRDRNLMALQSELIGAHATGIRNVLALTGDPPRLGDYPNA
TAVWDVDSIGLIAILKRLNTGKDWAGTSIGRASRFFVGCAVNPTAEDIDLEVERFRRKLD
AGADFVMSQPLYELETLERFLDRVGAIPVPLILGIMPVQSFKHAEYLHNEVPGITIPRSL
LDRMERAGESGMAEGLAQAREFLSQAKQYVAGTYIMPSFGRYEQVAELVKAL
>A0A8F8EBP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter vibrioides|TrEMBL
MTLPPTRRVIGPVARAGERTGRPRVSFEFFPPKTPQMEESLWQAITRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASREEVDEVIREYWETGVRHIVSLRGD
PPPGEGGIGGVYVPRADGYANATELTKAVRAIAPFEVLVGVYPEKHPESPSLEHDIDVLK
QKVDAGATLGISQFFFDLDAFLRFVDKVRAAGITIPIVPGIMPVTNFAGLKKMAAACQTA
IPSWLGNLFDGLENDAETRRLIACSVAAEMCAKLQEQGFEDFHFYTLNRADLVYAICRVL
GVREISPAASEVAA
>A0A2E5KYS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MIQSIVDLKIVMSHCRNGRLVLWLPNAGLNLEPSEKLQNSLRGMLKNSDRFLTAVEIETS
RGLLMSEASRKTAELAKSLSEFDRVDFVALTDNPGGNPHIRPEVLGQDLLFRGRDVVINM
SCKDYNRNGIESRLWALGSQGFTNVLALSGDYPIGGFQGQAQPVFDIDSVGLLELMSQMN
DGLPNQMWGSAGREDRLEKTDFFAGCAVSPFKKFEGELMTQYFKLAMKVRSGAKFAVTQI
GYDSRKASELHQYVNSNNIDIPLIGSIFILTAPAGRFFNRWGVPGVWVSDELRDIANKQA
KSKDRGRAFFSELAAKQIAILRGIGYRGAYISGRPQLKRIQSILEMADSFGENDWKEFAK
EINFSQKDEFYYYEQGDNAGLSSDVVNKSYLSSKTKSARSKAKFSVPIQFRLGKFVHDRV
FDKHSTGFKVGRSVYRQIDKSKKLSGVAHVLEQVAKVPAYNCRDCGDCSLPDIAYLCPES
QCVKSQRNGPCGGTKAGKCEILDQKCIWIRAYDRLKPFGDEEKMLQRPVVFRDGSLKNTS
AWGNTFLSRDHHGRQNPNTVDGEA
>A0A081AZI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora parasitica P1976|TrEMBL
MGKIIESIRSAYAARADDASARPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGAERWSPVEGGLSNAVDLIKLIREEHGDYFCIACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIQWISDCKDAGITIPILPGYLPIQNYSSFCK
FTSWCKTRVPEKVLTALDAIKNDDAAVRRYGTQLAVETCRRLLAAGVNSLHFYTMNLATT
VTQVLEGLQLLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRTELWGTPQTEEDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAAIRENLQWLNSNGFLTINSQPRVNGAPSSDPSVGWGGDDGVVFQKAYVEFFVA
PEKIAHLVKVMRRDYPQLSFHALNRRGDEHRNTPLHSVTAVTWGVFPGIEIVQPTVVDSD
SFAAWKDEAFELWQTQWASAYPEGSCSREVIQHIYDSYFLVNIVDNDYANDDSDIFSIFT
RIITEAMDKEELRTRVLELEARREKMFDTLASFQSLQKDLNGELRAAHSELAGVRGENLQ
LKEKVRQLEAQLALASL
>A0A7C3IK51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MHGPLLIRDVLAQRQAQRRAAVSFEFFPPKTEEGERTFFDVTLPQLAALKPDFCSVTYGA
GGSTRDKTLAIVETIQRRYGLPSMAHLTCVGSTVEQLREIIRQARARGIVNILALRGDPP
AGAREFTPPPGGFTHAWQLVRLLREMGDFCIGVAGFPEGHPACAEGKYADWRYLKAKIDA
GADLVITQLFFDNADFWEFRDYLTRLGVRVPILPGVLPILGLQQVQRLTQLCGARIPDPL
RSRLETLADDEEGSIAFGIEYASQQCQDLLRGGVPGIHFYTLNRVRSTRQILANLGLV
>A0A7C3LL38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRKRDAEVTELLPDLSGRPLRAGGRLERVLRSGLFAVTAELNPLDTTDPQEIYDAALALA
DAVDAINTTDSSGANVHMSSLASSALLLRAGYDVVMQIGCRDRNRIALQGDLLGASALGV
KNVLCITGDDVSVGDQPETKRVFDFDSMHLLRTARIMRDQGVFLSGRKISVPPALFLGAV
ENPFAPPLDWRAERLAKKVEAGAEFIQTQYVFDVEVFREFMARVRDLGLLGRVYILAGVG
PLKSPKAAEFMRTRVPGVVIPDTVIERLKKTPRERWHGEGIQICSEIIEQVRQIEGVAGI
HVMAYRQEEAVAEIVQRVGLFPRISPAEIGAG
>A0A6N6L1V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTENYHAGSRLEKTLRSGKMAVTVELSAPDSVDPESVYQPAALLPDYADGVNATDASGAN
CHMSSVAMCSLLEQKGYEPVFQVSCRDRNRIAMQGDMLGAAALGIKNVLCVTGDDVSSGD
QPESKAVFDFDSVQLLRVFRSMRDQGIYLSGRKIEARPKVFLGAACNPFAKPYDWRPQRL
AKKQEAGADFVQTQYCFDVPLLKRFMQQVCDMGLNEKVFILIGVGPLRSARVAEFMRTKV
PGIHIPDEVVERMRKAPKEDRIKVGKEICVEIIQQVKEIKGVSGFHIMAYRQEEIAGEII
EEAGVWPRLPIPH
>A0A3L7YD56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLYPAGPDYFAQLTPDWLATGARIVGGCCGTTPAHIAALRQALDTPRKAAVHSGSHRPST
PAELLPATDAPTKLATQLQSKRFVITVEMSPPKGYTPHKVLAGAHMLAEAGADVINVADS
PLARMRMSPWAVCHLIQQQVGIETVLHFPTRGRNLLRVQGDLLAAHALGVRNVFVVMGDP
ATIGDFPQAFDTFDVAPTALLQLVKQRFNAGVDQAGQEIGQPTSFVAACALSLSAPDPAR
EIKLLRKKLECGADFALTQPVFDAQVARDFFARYAAEHGPLQLPVLVGVLPLYSERHAGF
LHNEVPGVHIPEEIQRRIAGAADAPAEGVRIALELLAELRATTPIRGAYLQPPFRRYELA
AEIIEHTRAQD
>A0A2D1TZK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens|TrEMBL
MRVDEVFKQAASQGTTPVSFEMFPPKGELTLDTARKVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRSHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNLSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A535JVG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRGSTELEDLSEMERSFSLSAFASLLRSGEFVVTAELNPPKSAAANVVRRRGEALKGVVD
AVNVTDSNRAVVAMAAIPAATIVRSSGVEPIVQITGRDRNRIALQADLLGAVAIGIENFV
FMSGDDPKQGNHPDAVNVKDLDGVGLVKMAVGMRDQARFLSGDEIKQPPKMLVGATASPF
TKPMEADLTKTLEKIAAGAEFIQTQPVFELATFSQWLVEVRRGGAREVPIIAGVLVLRSA
EQAERMAKVPGLALGTDVLERMKKAGDAEAEGIAMAVEMVKALKALPGVRGVHL
>A0A1C0U8Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus australis subsp. thailandensis|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTVEMEKTLWKSIGRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELRKIARDYWDNGIRHIVALRGD
LPDNSEKPKMYGVDLVELLKEEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQLQRFAVMTNVRIPSWMTRMFD
GLDDDPESSNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A4R5UUF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus aquimaris|TrEMBL
MKITDHLKNAKSTLFSFEILPPLKGQSLKELLEGIEPLMEFKPPFVDVTYHREEYIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFHVDAVPHLLCGGFSKEETENALIDLNFIGVENV
LALRGDAPKTEGKFIPEKNGHHFASELVDQIIRMNQGKYLHEETETSFHTNFCVGVAGYP
EKHFEAPSMKFDLKYLKEKVDRGAEYIVTQMFFDNEKFFEFERNVRAAGIDVPIIPGLKP
ITTLSQITMLPRTFFLDLPDALTDELLKCKTNAEVKEIGIEWAIQQSKELVKAGVPSLHF
YTMSKAEATYKIAKEVF
>A0A535GR54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSTFTQLLRRGDFVVTAELNPPKSAAAQVVRRRASILKGYVDAVNVTDSNRAVAAMAAIP
AAVIAREAGVDPIVQITGRDRNRIALQADVLGAAALGIEHFVFMSGDDPKQGNHPDAVNV
KDLDGIGLVKMAASLRDKAQFLSGDEIKEPPQYTIGATASPFTKPMESDLRKTTEKIAAG
ADFLQTQPVFDLATFSQWLAEVRRLAGRHVAILAGVLVLRGAEQAERLAKVPGLALGTHV
VERIRAAEDQEGEGIAIAVETAKSLRSLPGVNGIHLYAIEWPQGVTKVVRAAGLYPRPLL
KESKSA
>A0A536PKS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSGLAALLKAGEFVVTAELNPPKSASAEVVRRRASALKGAVDAVNVTDSNRAVAAMAAIP
AAILVRESGVEPIVQMTGRDRNRIALQADVLGAAALGLENFVFMSGDDPKQGNHPDAVNV
KDLDGVGLVKMAAGMRDGKFISGDEIRYAPSYFVGATASPFAKPMSADITKTIEKVEAGA
EFLQTQPVFDLATFSQWLAELRRTDAREVAVIAGVLILRSGEQADRLAKVPGVALGPEVV
ERMKKAADGEAEGVAIAVEMVRALKALPGVRGVHLYAIEWPEAVPQVVERAGLLPRPEAK
VAVS
>A0A535C5W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTKAAAIGGSPVAIGSRLRRALDAGRSVITAELAVPATVAHELILERAKGLLRPQIVAMN
ITDGLRGRPALSPIAAAAILTHADLGVEPIVQVVARSRARNALIADLLGASALGVRNLLC
MTGDVPESSADIQDVDVFALIGLARGFPAGLGTELLGTAEPFCVGVAWSPFARDPDHEAD
RLARKHSAGALFVQTQPVFDAHAFAAAIDRLPRTLADLPIIVGLAPIRSCDHARRLGAIP
GIVVPDRLLALLDRASDEADACERYWAYLDAELDWLTRNVPHRGFHLMPIGHSKRGIRQS
SSFDRLYAAVTRALDAAPPKPADVAAPVDVSVFGTSAG
>A0A2E5JX28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MFIKDILQQNPKSFSFEFFPPATPEGFDTLFKTIEDLKLLDPSFVSVTYGTGGKTREKTV
SLVSDIVNKIGTEAMAHLTCLRSNKEEIDEVLTSLSTNNVSNIMALRGDPPKGYSSFPED
EGHFTHAIQLVEFIKSNYKQCIGIAGYPETHQEAVNAQTDMEYLKLKVEAGADFIITQLF
FDNSSYFEFMDRAIAIGIKVPIIPGIMPITNVNQIIRITKLSGAKIPKTMLDKLYSIQDD
PKSVEQFGIEFSLMQCQELLKNNSPGIHFYTLNRSRSTWEIMKSLK
>A0A497BSY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSKLRQALESGKFVITGEVGPPKGVDLGACLHHARELRDKVVAINVTDLQSAVMRIGSMV
VCAKLVEQGLEPVYQLTCRDRNRLALQSDLLSAWAFGIKNVLCLTGDHPALGDHSDARPV
YDLDSVQLLKAASTLNNGHDMAGHELEGKPDFFLGAVVTPAADPLEPQKIKMKKKIEAGA
RFFQTQAIYEPERFEKFMNQVQKLGVPVLAGMVLIKSPAMARFMNANVAGINVPDSIISE
MEETRKEDRKKKSVEITARIIRQVKSLCQGVHIMPLGWDELVPDVIAEAELK
>A0A1H8QQ99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sinopsychrotolerans|TrEMBL
MKVTQHLEAAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVD
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKQGGNDFAVDLVKQINQLNCGKYLHDVMDVDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDQCKNNTDIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A522ATG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSSSSSARRRSRIPRSRRVALLRRLVGRAEPGSDLAAPAREALTEVLANPTFELIPLKNV
HDQAAFLPAGAKVSVTASPAKGIEATLDLSAALEANGFRVIPHLSARMIRDRAHLADVLA
RLRASGIDRAFVVGGDAEDPGQFLDGLSLLRAMAELGDGPSDIGVPCYPQGHAVIPQPAL
LQALRDKAAFASYMTTQLCFDPVAIRAFIAARRAEGIALPVKIGIPGVAEVPKLLSISAR
IGVKDTGRFLSKNVRFVSELVTSGGIYRPTGLLEKLGPVIADPAANVIDLHVYTFNQVES
TETWRAGYLATLRGE
>A0A536QBA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSAFASLLRSGEFVITAELNPPKSAAANVVRRRGEALKGVVDAVNVTDSNRAMVAMAAIP
AATIVRSSGVEPIVQITGRDRNRIALQADVLGAVAMGIENFVFMSGDDPKQGNHPDAVNV
KDLDGVGLVKMAVGMRDQARFLSGDEIKQPPKMLVGATASPFTKPMEADLTKTFEKIAAG
AEFLQTQPVFDLAVFSQWLVEVRRGGAREVPIIAGVLVLRSAEQAERMAKVPGLALGPDV
LERMKKAADAEAEGTLIAVEMVKALKALPGVRGVHLYAIEWPEAVARVVEAAGLLPRPQA
KVAVGT
>A0A3C0XJ28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIVDAFGPGKPPVISFEFFPPKTPDAEARLFETVAQLAPLRPTFVSVTYGAGGATRRLT
RDIVARIKREIGIEAMAHLTCLGHTADELAEILDALTAAGIENVLALRGDPPKGQTTFTP
TPGGFAHGAELAGFIRGRWDVCIVGAGYPEKHLEAPDPETDLHHLTEKVANGAQVLITQL
FFEPQTYFAFVERARAAGIGVPIVPGIMPITNVSQIERFTSMCGASIPASLRELLAGVRD
DDAAVTAVGIEWARDQCRALLAGGAPGLHFYTLNRHHSAQEILGLLRAEGRV
>A0A3C0XQ67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
GAHAEGIRNVLAVTGDPPEVGDYPGSQGVYEVDAIGLVDVIARLNRGEDYYGRAIDAPTS
FFPGVAVNPSADDLDTELERFERKLEAGALFAMTQILFDLSYLERFLDHYGGTSPVPLLV
GLWPIRSFELAQRVHNEVPGIVVPEAVQERLRTAGADAPRVGLDLTRDLLAQARDLAGGV
YVVAPFRRPLGVLELFS
>A0A3N4PMR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga lutea|TrEMBL
MESTLRDKIINRQPGLVFYSLTPPKVTTEAERLIIIAANQVERLKSVAIDGLILYDIQDE
ATRTEKERTYSFIPTIPPETYSKEFLSGLNVPRIIYKSIANKTNDQFAGWLRENGEIEYT
VFVGASSHQQVEETKFSLTDAYQLRKEAFDHITLGGVTIPERHRKKGDEHIRIFDKMDKG
CSFFVSQCVYNLNESKNLLSDYYYHALETGNRPAPIIFTLTPCGSLKTLQFMEWLGIEVP
RWLYNDLKHSKDILEASVTTATHIAEELLAYANLKNIPVGFNIESISIKKDEIAAAHVLL
KNVLALVRPEGKHAFVKELGSIVE
>I8TUJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus oryzae (strain 3.042)|TrEMBL
MHIKEKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAAEGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLLPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIKDLSRLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLIE
LNNRGILTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDSWYLVNIVNNDFHNTYDLFELFKDLNVRDFDVEVAADNADLK
SQENETAETTAN
>A0A439EU34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylella fastidiosa subsp. sandyi|TrEMBL
MIPISFEFYPPKNDDQRAQLDRTANRLRAFAPEYVSCTFGAGGSTLSYTSETVRHLSQHH
GFDAAPHLSCVGGSRQEIRELLKLYRAIGCQRIVALRGDLPSGMGHPGDLRYAADLITFI
RAEHGDHFHLEIGAYPETHPQASNTLNDLHYFKAKVDAGADAAITQYFYNPDAYFHFVDA
VQRLGVTIPIVAGVMPISNFDQLRHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVV
TALCERLIAGGAPGLHFYTLNLAKPSTQVLQRLGY
>A0A2E0CUP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLNTLEIVPKQYEKIFSLPKNMFGEIYVAFIPGDQVDNIISSCKQLVNKGYSVIPHLPAR
NIKNEKELEYYLFQLNKLNIKKILAIGGSSLEKNPTFSSTYELFKTGIFENFDFDQINIA
GHPEGNPFDKNSNENLKEKLNWLVNKNYKCNIVTQWTFDPKQANIWLEKMNKDISNISNN
IEIHMGIAGPAKFTTLLRYAKVCGVSASAIIAKNKGLSLTKLLKHNPKEIIKSIVGYDNL
HFFPFGGINELVEWKKI
>A0A535H615|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
ALGIHNLVLMSGDDVTAGDHPEARRIYDIDSMQLVEVAAAMRDRGTYLSGRKLEQAPAFF
IGAVENPFAPPLEFRPLRLQKKVQAGADFIQTQLVFDVPIFARFMAMAMDLGLSDKVFII
PSIGIPRSARGAHFMREKVPGLHVPDALVARLEKTPPGRQAEEGIQIAVELVNAVREIPG
VAGVHLIGIKWEEGVVQVADAAGLLPRPTLSPIATIGGSR
>A0A535SME2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIVDMLTRSRPSVSFEFMAPRDESEVDVLERTIAALAGHGPDWVSVTYRQRTGEKTLEL
VTRIKRQYHIEAMAHLTCANTVDRTRQVLNWMEREGVANVLTLRGDPPSAGEPFVPADPR
LTHASDLITLVRGSGYRFGLGAACSTERHPESPDLEHEFRYMQLKVEAGAHFLITQLFFD
NRFYFDLVARARAAGIKVPIVPGLMPVPSRRSLAVMTAMSGATVPAALQAEIDGAADDDA
IRALGVRHCIAQCAELLEGGVPGLHFYTFNRARAPIEILAALRGQQLLAS
>A0A4U7B9L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elsinoe australis|TrEMBL
MHISPKLRQSAEERRPTFSFEFFPPKTAQGVQNLYDRMDRMHDFGPTFIDVTWGAGGNLS
HLTTEMVKVAQSVYGLETCMHLTCTDMPRSKIDDALRDAYNAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDHRDQELLIKHLKEKVDLGGTF
VVTQMFYDADIFVDWVKKCRAAGINVPIIPGIMPISTHAAFLRRANWTKCHVPEHWTKAL
EPVKNDDAAVREVGKGLIAEMCRKLLDNGIYHLHFYTMNLAQSSRMVLEELNILPCAESP
VEKPLPWRQSLGLKRREENVRPIFWRNRNRSYIARTQEWDEFPNGRWGDSRSPAYGELDA
YGIGLKGTNEQNRKIWGSPKKLRDIADLFARYIEGKVESLPWSESPITGEADVLRADLAN
LNRRGILTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELLTRIERDD
DVTYFAVNQDGELKTNSPSDAGPNALTWGVFPGKEIVQPTIVETVSFMAWKDEFYKLGRD
WSRCYDNDDPARYLVDGMMKEWYLVNIVHNDFRRERTIFPFFDGLEVPNLDEPAAIDDGY
LNGEKLHERSDSARINRHSTPHGDKTSESATNGEKTKEKASEPAPSSENWVGLGINPKN
>A0A653MRV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 9R|TrEMBL
MKVTQHIENAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYVN
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPTNGGNKYASDLVSQIYQLNQGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQTDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVERHLQVLPQIFRIDLPEDLIAAVEKCKNNAEIRQVGIEWAIQQSIELKAAGVPVLH
YYSMGKSENIRQIASQIF
>A0A4Y9FVR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium paludicola|TrEMBL
MTGKDIPGLHEAQDVIPPGTRVNVTFLGNEDLEMRVAAAKAVVDAGFIPVPHISARRLSS
QAQLEEFLDRLQQVGATEHVFAVGGDPATPEGPYDSAYDVIRSGVLQSYGVREVSISGYP
EGHPDIATDVLWEHLEKKTTSLRDQGLGAVILTQFAFDTDPVTTWIGDVRNRGIDATIRI
GTPGPAGIKRLLSFARRFGVGANAMIVKKYGFSLTNLLGTAGPDTFVTELGDLLAADPRA
GDVKLHMYAFGGLRATAEWARDYQRRVS
>A0A5N0VLR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis acidicola|TrEMBL
MPQDTALAAATALLGDFSLEMTGKDIANLTAARALIPAGTRVNVTYLGTEDLAMRLAAVK
AVQDYGFVPVAHISARRLRSPAELEEFLAALQSTGASENVFVVGGDPTRPEGPYEDSLAV
LRSGLLQRYGVRHVSVSGYPEGHPGIGDPVLWSAIEDKNAVLRAQGLAGTVITQFGFDSD
AVLAYVDEVRKRGIGLPIRVGVPGPAGIKRLLSYARRFGVGTSTGIAKKYGFSITNLLGT
AGPDRFLTALAEGYEPHRHGEIKLHFYTFGGLEATSGWIADFRARN
>A0A535XA14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MWDVKSPGFIRIIKQLNQGVDWAGNSIGRPTNFLVACAVNPMADDLDYELDWYYQKVDAG
ADFAITQPLYNMEQLDRFFSRVPHPPIPTVVEIMPLQSYRHA
>A0A535X0F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSSTCRSRWIGSSRERRPGSTCCVDVTGPRRRAGWPMSTPSRLAGLLGEGRFVVTAELSS
SNSADPEATWRRAAVLGGSVDAINCTDNTGAHVHMSSLAAAHLLVEKGLEPIMQLTVRDR
NRLALQADLLGAAALSVRNLVLMSGDDVTAGDHPEARRIYDIDSMQLLEVASAMRDRGTY
LSGRKLEQAPSFFIGAVENPFAPPLDFRPLRLQKKVRAGADFIQTQLVFDVPIFKRFMDM
VGELDLQRKVFIIPSIGIPRSARGARFMQQKVPGLHVPESLVSRLERTAPARQAEEGIQI
AVELVRAVREIPGIAGVHLIGIKWEEGVVQVAERAGLLPRPTLSPLATVGERG
>A0A535YB37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MACWPSAAPCSTTTARAWPACTASWRATSPSTALIPGAGGCRPTATPSSSCPTRGRDSVA
HSATVAYSATAHVVRPVGTRGVGRGLAAFLRAPRYEIFPTDDILAVVAQYVPKEVTITVT
ASPRRGLPATVHLAVNLARLGYTAIPHLSARLIRDRVELGQILEAVRAAGIHGIFVVAGD
ARESAGEFPDALSLLAALPPDHGLTEIGVTGYPERHPFIHDDVTIQAMWDKRRYATYIVS
NMSFDPDTVKGWVERVRRRGVELPIYVGMAGVADPARLLRLSTKIGVAESARFLRGHPSW
LARMFRPGGYEPGRFVSALLPDIAQPDRRIAGLHVFTFNEIEPTERWRREMLLRLTQGEG
A
>A0A1E2YD18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccidioides brasiliensis|TrEMBL
MERISDKIAALPQDANYFSLEFFPPKTPMGFLNLKARLERMSQALRPLFVNVTWGAGGST
VSKSLELAEMCQRQLGLTTCLHLTCTNMNRTLVDDALAEANALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTHAVDLVRYIRRMYGDYFCIGVAAYPEGHSDESHPEVQDPARDLPYL
VEKRKAGADFIMTQLIYDLEAYKRFEEMLRNHESGVFKTIPIIAGLMPIQSYHILTRTTK
LSHAKVPPDIMARVEEVKADDEAVKQIGIDILCEIVNGIKNLPCPGPRGLHFYTLNLEKA
VAFIVERCNLIPTSSEPSSDSDTELDSAVFITPGMKNGVPLISKRRASSLNSQPHNRLIV
DHPASLSIGAPSSQTSTTHETQALGAGMLALNPPHQSTALQISEGMGALGREATWDDFPN
GRWGDARSPAFGEIDGYGPSLHVNANVARQLWGYPTSREDINKLFHCHVSGELHIVPWSE
GGSAEDSGGLNAETATIREELLQLIDGRGWWTLASQPAVNGVRSDHPIFGWGPRGEGFVF
QKAFVEFFCSGQDFEKILKPIFKRHGQDELSWFATNASGDFQSSSSFTGTTGLDDAVPDY
SGAASSNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGHEAFRIWDEWRRIFRRGSPTEQL
LDQLKKDAWLICVVGQKFGAGCGGKEASEAEKFLWRVLAGKEDTEANPTGLY
>A0A0F7EIT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus laterosporus|TrEMBL
MGKRDLRAYLTQHVLVGDGAMATQLYEQGVPIGVSYEELCLSNPQIIRNVHAAYYGAGAR
LIETNTFGANRDSLSRYGLESKVTRMNRAAVTIAREAVGDDAFVVGAMGSIIAGRVRTKQ
IDQFKDQFEEQATSLLHAGVDGILLETFLDVDELLLALEVIRPLTELPIIAQLATLEVGT
TRDGHSLTYAFQQIKDAGADVIGLNCRLGPAEILRSFEATVCPDDVFLSAFPNAGRLGMA
DGTLSYKSSPDYFAESALRLHEQGVRLIGGCCGTTPEHTKAIVEKLAGRKPLPRVNPPAP
IHSERIEVQAVQKRLQPSIIEEVKQHPTIIVEFDPPKDLHTEDFLQGCCALHDAGANAIT
LADNSLATVRMSNMALGAMMKRLGIEPLLHIACRDRNLIGQQSHLMGLHALGIDQVLVIT
GDPSRFGDLPGASSVYDVSSFDLIRMVKQLNQGYAFSGKQLKQHAQFIVGAAFNPHVRHL
DAAVARLEKKVEAGADYIMTQPVYDVETIVQIYEATKHIRVPIFIGIMPLTSSRNAEFLH
NEVPGIKLSTFALEQMKLFTGEAARQEGNRMAKELIDATLQYFNGIYLITPFNYYQMTVE
LTQYIRQQEQVKAGFKEVSSS
>A0A1U7RDT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alligator sinensis|TrEMBL
MVNETPSSGSSGSRSDGGSSSGGESSKDSSRCSTPVLDAERHERLREKMRRRQESGDRWF
SLEFFPPRTANAAVNLISRFDRMAVGGPLFIDVTWHPAGDPGSDKETSSLVIANTAVNYC
GLETILHMTCCNQTKEEITAHLHKAKHLGLKNIMALRGDPIGEEWEEETEGFNYAVDLVK
HIRCEFDDYFDICVAGYPKGHPDAESYEADLRYLKEKVCAGADFIITQLFFRSETFLQFL
KDCQAIGITCPVVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVE
LAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKM
WGEELISEESVFEVFTCYISGEHNKNGHKVTCLPWNDDPLAMETNLLKEQLEKVNRRGIL
TINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLRVLRKYELRVNYHI
VNARDENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKGEAFALWIEQWAKLYE
EESPSRIIIQYIHDNYYLVNLVDNDFPLDSCLWQVLDDTFELLGAPTPC
>A0A3A6MYD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbus sp|TrEMBL
MKSGSNLERVLTSGAFAVTGELGPPKNSDPEVVRSKARLLKGNVDAVNITDCQTAIVRMS
SIGAGLIAKEEGLEPVIQMTCRDRNRIGMQSDILAASALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMVRGMRDAKKFQCGEEIQGPAPKLFIGCAANPFAFPHEFRAVRLGKK
IASGADFVQTQIIYNVDRFAKFMAMCRDLGLDKKAYILAGITPPKSLGMARYMHNSVPGM
EVTDEVIKRLQGAKNKQQEGISIAVDIIHQVKEIKGVAGVHIMAIEWEEAVQEIAERAGL
LPRPTFAETTAPAAALAAAPAPETISVRAESDAVLEEAKAEAARIIAAAREEAVAISRQA
AGSTPSTETIAIATDDAGEHEMNEKERQMALDAVKQGLDALKKAYGLSDDQFAALLKFVD
AEAILRREPPKAAAAPAAPATPVAAAPVAPAAPAADAAKAEAEAKAKAEAERKAKDEAAA
KAKADAEAKAKAEAAAKVEAEAKAKAEAERKAKDEAAAKAKAEAEAKAKAEAAAKPAAPA
PAAAPAPAAAPAVPAELAVGELKAESEPLAQRASKVPAASYRAAYSGKIREVVLGNGDKT
VIVGGSEVLPFHLFEGNMPRKPLIAMDILDIKPDNWPATLTKYYEDVLGNPVAWAQKCVN
EYRAEALNISLVGTDPNGMNRPSSEAAKDAAAVINAVEVPIIVWGCGNNEKDTETLREIT
AIIGDKKVCLAPLEDANYRAIGATAMAFQHPMVAASPIDVNLAKQLNILLENLGVPLSTV
LMDPSIGALGYGIEYTYSVMERIRLAALTQKDEKLQVPIICNLGREVWKTKEVGLPSDEL
LGDQERRGIMMEAMTAVCMLLAGGEVLIMRHPKAVNMTRSLITGLMA
>A0A7X8WEH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
SNAEITEIGVRWCIAQSKELHEAGVPAIHYYTLGKARNVAEIVRAVY
>A0A2D6LCR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MTSLRDIVTEGDRFLVGAELVSARGPIKPGEGGKIMEFVDGLASADYVDWISVTDNAGGN
PMQAPYILGKAIMERGKQAVIHITCKDNNRNGLEALAWMYTAEGLDNLLVLSGDYPIDGQ
NGIAQPVFDIDSVGLLKMLSDMNKGLTVKGRKPGTTMVLEKTNFFLGCTVSPFKLTEAEQ
MMQYQKFRAKAKAGADFIIPQVGYDIRKSQELMEYMKEHDINLPLIGNIYKLGYGVAKIF
NRGFIPGCVVSDELLARIEKERKADDRGKKYFTHLAAMQFAAFKKMGYRGGYIGGVEKYK
DFAAIVDAAAGYEDVPLTDLVKDLVYPRTAEFYYFARDNKTGLADVSKKNPILEERVKSR
YKKNVNFGYRFSRMIHALAFSEKSPFQRLGRPIFNFLEKHEKLDRAAYFNERMAKATIFE
CKECGDCSLADIAYLCPQSQCQKNQRNGPCGGSRDGLCELSACGKECIWVRAYDRERYFS
KDLPNLLDREPVIKDASLKGTSGWANYFLNRDHFAKKNGDNGSRH
>A0A7Y6E9U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. C2B4|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLREYKAAGINRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGNHFHIEVAAYPEMHPQARNFEDDIANFVRKANAGADSAITQYFFNADSYFY
FVDRVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A4R3TAU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Longicatena caecimuris|TrEMBL
MHPLFMKQKRLLFDGAFGTYYASLYGNEEPCEMANVKAPTRVAAIHEEYLKAGANAIKTN
TFAMNEAVLDCSKAKREELLRQGYRIAKRVATPYQASVFADIGPCVETRTRSAFTQYKEL
VDVFLEEGADCFLFETLPNDHGIHEIAAYLKERCPHVCVLVSFAVTADGYTQQGVPLTKL
VKAAHEDENIHGFGLNCICGPMHMRRLLKYFDTKKDTILIMPNAGYPTILANHTYFRDNS
SYYAQEMEKISSMGVRILGGCCGSKPSYIQKIKERLQEEAVLSLPTPAANDPVLYKDCNP
LRKKLQRKEKVICVEFDPPMDCRIERFMNDAEYLKEQGIDAITIADCPIARARVDSSLLA
CKLHRELGIDVIPHMTCRDRNINATKALLFGLNIEDIYNVLVVTGDPIPAADRQEVKGVF
SFNSQLLAGYIRDLNETTFPHPFLIFGALNVNAANFKQELLKAKQKIQQGVQAFLTQPIH
SAKGLQNLQQAHRELDAWILGGVMPIVSYRNALYMKNEIAGIEVDDAILSRYEHKNREEA
AVLAVTIAKATIDEMASFVDGFYLITPFHRVEIMQQIIAHIQQMDD
>S8B8S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dactylellina haptotyla (strain CBS 200.50)|TrEMBL
MHIKDKLAACEKAGKPCFSFEYYVPKTAQGVQNLYDRMERMGSFGPQFIDITWNAGGRLS
NLTTEMVNVAQTVYGLETCMHLTCTGMEKEKVDNALKEAYNGGCTNILALRGDPPRENEK
WSAVPGGFRYAKDLVKHIREKYGDYFDIGVAGYPEGCDDEVDPDILLDHLKEKIDAGGTF
IITQMFYDADIFLDWVQKVRAKGITVPIIPGIMPIHTYAAFIRRATWTKINIPEKWMTAL
EPVKNDDVAVRDIGRDLVVELCQKLLAAGINQLHFYTMNLATATRMVLEGLDLMPSLDSP
VPPALPFKSSLGLGRREENVRPIFWKNRHKSYVARTQEWDEFPNGRWGDSRSPAFGELDT
YGIALKGTTEQNIKLWGHPETAADIADLFVQYMDGKLDSLPWSDSPIDSTASSIRARLSD
LNKRGFLTTNSQCALNGVKSSDPTHGWGPKNGYVYQKMYIELLVSPDVLTELITRIERSD
DLTYYAVNKAGVLHHNAPAGGGPNAVTWGVFPGKEIVQPTIVELISFLAWKDELYRLGED
WAACYPQSSASRHIISSVMENWSLVNIVNNNFLDNDSIFELFDGLKVEGLNEKIPVDEYL
QSLKVPNGTITNGGTHAVETNGVPAA
>A0A2E3KPR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium|TrEMBL
MTNRNIPINFEFFPPKTEAGQAKLVAVANVLADEQPEFFSVTYGAGGSTRDGTRRTVLQL
NNEVGVPAAPHLSCVGDSREDLRTLLNDYRAQGIQRIVALRGDLPSGMGHASGELRYANE
LVEFIRAETGDHFKLEVAAYPESHPQAPNFETDLKNFIRKAQAGADSAITQYFFNADCYF
HFVDRVRQAGVDIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSDSIKAF
GTEVISQLCERLIEGGAPGLHFYTLNQAEPTVAVLRNLRG
>A0A0T6VXN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. P4B1|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRAEIGELLDVYKENGINRIVALRGDLPSGMGASGELRYAN
ELVEFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEDVVTEMCEKLLKAGAPGLHFYTLNQAEPSISIWKNLGISDREKIAF
>A0A422LZZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPHACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERSQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFPGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>F9FK60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum (strain Fo5176)|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A2V4JWH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MB-090624|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVQVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRAETADHFHLEVAAYPEMHPQARNFEADLGNFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTTSIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLALWNNLKLPR
>Q2RU65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1)|TrEMBL
MTVTASPLIARPRAPRALSVSFEFFPPKTDRMRDQLWDCLRQLEPLEPSFVSVTYGAGGS
TRERTHETVARIAADTTMKPAAHLTCVEATRAEVNAVAQAYWQAGVRHVVALRGDPPTLG
GAYVPHPGGYAYALDLVKGLRDVADFEISVAAYPEVHPQARSAAEDLDNLKRKIDAGATR
AISQYFFDVDSYRRFMDRVLAAGISVPVVPGILPVGNFQTVLKFSNACGTRVPKWMHELF
AGLENDPETHRMVAATLAAEQCLSLFEDGVDCFHFYTLNRADLVRAVCHMLGLRPAAIPT
ASRLAPDQGAGTIALGASV
>A0A494WRE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium scindens (strain ATCC 35704 / DSM 5676 / VPI 13733 / 19)|TrEMBL
MKIRDILKDNSPHVSFEVFPPKTDAGYEGVRAATEKIAALRPSFISVTYGAGGGTSRNTV
RIASQIKNDLGVTSLAHLTCVSSTKDEVHGVIGQLKEQGIENILALRGDIPADGEFPLPN
HYRYACELVEDIKSQGDFCIGAACYPEGHVEAAHKKDDIMNLKHKVDCGVDFLTTQMFFD
NNILYNFLYRIREKGITVPVLPGIMPVTSAKQMKRICDLSGTVLPERFRAILDRFGEDPD
AMKQAGIVYATDQIIDLIANGLNHIHIYSMNKPEVAEAIIGNLSTIIKA
>A0A209BLT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CS227|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A0S8DS91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium SG8_47|TrEMBL
MESQSNYPRTFSCEFFPPKTAEGAEKLRRARDKLAAIRPDYFSVTFGAGGSTQAGTIDTV
VEIQQAGYQAAPHLSCIGTTREGIREILQRYMAEGIARIVALRGDLPSGMGVSGEFRHAN
ELVAFIRAETGDHFHIEVAAYPEFHPQAPSAEDDLNNFKRKVDAGANAAITQYFFNPDAY
VRFVDDCAKLGVNIPIVPGIMPITNYKQLARFSDACGAEIPRWIRKRLEGYGDDVDALRA
FGLEVSTELCRRLLELGAPGLHFYTMNQSVPTLAIWENLGLDGDG
>S8A4J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dactylellina haptotyla (strain CBS 200.50)|TrEMBL
MQQKVTDKIKSLPKDATYFSLEFFPPKTQAGLQNLHARLSRMSKGLRPLFVNVTWGAGGS
TATKSLELASLCQSLDLTTVLHLTCTNMSKAVLDDALQNAKLMGIRNILALRGDEPRQHE
YLDVTDQVRVGNEETDFIYAIDLVRYIRAQYGDYFAVGVAAYPEGYAETSYPLQQNTSQD
LPYLREKTAAGADFIMTQFFYDVGAYLQFERMLREDESGVFKNIPIIPGLMPIQSYQIFR
RTTKLCCVNVPNSITERVEAVKADDEVVKENGIQIVTEMIQKIKNTPSDIPRGFHFYTLN
LEKAVAFIVERCGLIPELPTANDDSEVAVVDDEFPGHLTVNGGGAAGSSQRARRTSSIIS
DPHNRLIVDTVSSARSDLQAEAGEAGVPKILDPGSQEGQLAISEGEGSLGREATWDDFPN
GRWGDARSPAFGEIDGYGVSLHRTPTEALRLWGHPTSAKDISGLFVSHVRGELEAMPWSE
DALNPESLLIKDELVGMNSKGWWTVASQPAVNSARSNHPTFGWGPKNGFVFQKAFVEFFI
PDDEWVQLRKILEEKGGEDLSFYAGNKAGDFVTSMPSEAAMNAVTWGAFPGKEIVTPTII
EEVSFKAWRDEAFDVWSEWQRIYPLSSPTSKLLGELKNKLWLVTIIHHDFVNAEALWKGI
LGV
>A0A4V2RXX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Camelimonas lactis|TrEMBL
MMIAQGTRDGTRAAARQGGRPSRDNLRAPRASFEFFPPKTPAMEEQLWSAIRRLEPMRPH
FVSVTYGAGGSTRERTHATVKRIVDETALTPAAHLTCVAASRDEVDEVIRGYHAAGVRHI
VALRGDAIEGPGHAFHAHPQGYQSSADLVAGIRAIGDFEVSVSAYPEKHPESPDLDADID
MLKRKIDAGATRAITQFFFDNDVYFRFIDRAQARGVDIPIVPGLLPVQNFTQAASFAART
GASVPGWLAQRFEGLDNDPETRRLIASAVVSEQAAELIDRGVEDIHFYTMNRADLVYAVC
HLLGLRPAAGASSQPAG
>A0A1V0LL13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kosakonia radicincitans DSM 16656|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAVPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCAATGIDVEIVPGILPVSNFKQAKKFADMTNVRIPAWMSQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A800D3L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquificales bacterium|TrEMBL
MKICDYLKSGNFSLSYEFFPPKDVKGRKQLTETIEELIIYKPSFVSVTYGAGGTTRERTL
NTVKEIKEKFNLTVMPHLTCVAHDREEILDILETYKGLGIENILALRGDRPKDNPKKGFC
RYAVDLVRLIKETYGDTFCVGVACYPEGHQEAPSLEEDILHLKEKIDAGGQFAITQMFFR
NEDFFRFKELLAKKGIDVPILIGVMPITNFKQIKKFAQLCGATIPLDLAKKLSEVQDKPE
EVYKIGIEYAISQCEELLDYGVDGFHFYTLNRPDATKEVIEALRDKIFSLRKV
>A0A8J6U7F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzicola mucosus|TrEMBL
MNQFRFSRRPDIGDKINVSFEFFPPKSDEMEARLWETVTRLEPLAPDFVSVTYGAGGSTR
ERTARTIRRILNETNLTAAAHMTCVDASREQVDQVIAEFAGMGVKRFVALRGDPASGVGE
AYQPYPDGYANAAELVGALKRVADFDISVSAYPEKHPESPDFATDIDMLKRKVDQGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGILPIHNFGQVSNFSARCGTHVPAWLAERFE
GLEKDPQTHALVAAAVAAEQVMDLVERGIVDFHFYTMNRADLAFAICHMIGIRPRAIARS
ASAAAA
>A0A1B0ABV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glossina pallidipes|TrEMBL
MSSNITNTTHLGAHFLPKIATAPLESAKCSYEPKFRFSEQQLRKYPKTQQLKIAVAEKIE
KKEYFYGIEILARNHNPKLMLDYTKFGKMLPLFTSLVWLGLDYSRVTNVEEVESIRVAKK
LKDNQHEMLIAPHLSCYGLDTKRLKEFTELNFTNIVIVRGDQYDNEQEFKYASQLVAQIR
RECQDSITIAVAGHPEGHPNISTMQEDMKFLIEKINGGADLIITQVCFKAQALIDFIKSC
RLHSINIPIILGIYVPDNIKSLQFLMELTKIEMSEEDLQEYRYYASKGTAEFRFFAAQKV
TQMILTVLNTKDINIYGIHFFTMNKFGMVTKVLEELRKYIKI
>A0A814NV54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adineta ricciae|TrEMBL
MTLGNSENQTVPNSHNMHHHETNHETRHLTQVLKRAESEGTNVAAKGCCLQSTRYVSLTE
KIEKRIENNDRWYSLEFFPPRTPSGAANLIGCFDRMAVGQPLFCDITWHPAGDPASDKET
SSMMIANTMLNYCGIDTMLHITCYGAKKEAMLSYLNKAKDFGIRNLLALRGDPPVGEEWD
PNKSDFRYGLDLVKFIRQHFEDYFVICVAGYPQGHPDSTSYEEDLGYLKEKVDCGADFVI
TQLFFQAETFIKFESDCRAIGITCPIIPGIFPIQGYASLRNIVRLAKLDVPKEILACIEP
IKDNDEAIRHFGVQTCLDLCRDLLESGKVHGLHFYTLNREFATIEILKKLGLWLEEQPMR
ALPWKKTSSNFSRSKENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGMLTDYH
LFYMKLDASRDELLDEWGRELTSEEDVWRMFACYISGEKNQIGKVIRHFPWTDEELSSET
SLIQTNLVEINRRGILTINSQPAVNGKPSSDPIVGWGTLDGYVYQKAYLEFFTSADNIPA
LRHVLKSFPNVNYHFVNKSGKVNETNIDDEQPIAVTWGVFTGREIIQPTVVDSVSFMIWK
DEAFSLWTERWGKLYEPESRSHAIIENIADTYFLVNLVDNAYPEGSSLWTILEAMFEYQK
SAKNTNNAS
>A0A6D1T7Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. BH32|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6L9QJS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura bangladeshensis|TrEMBL
MRRARPDRAPTVRELLASGGRSFSFEFFPPKTDKGARNLWRTIRELESLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPDGVEYAAELVRMIRSYGDFCVGVAAFPYKHPRSRDVDSDVRYFIEKCRA
GADYAITQMFFRAEDYFRLRDRVAAAGCDVPILPGIMPVTQMSTIERSEQLSGAPFPPEV
KARFEAVADDPEAVRRLGVEHAAELCRELLEQDAPGIHFITFNKSTATREVYSLLGAGEY
GAKGSVPPMTA
>A0A6N2W2U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MNNTKYTKEQIRERIQQKKILFDGAFGTYYGGKYDTRQLPELANLEAPERVKEIHREYLE
AGAQILRTNTFAANSFCMDIPREQIGETLRSGLRLAREAVAEWRETTGETKEIYIAADIG
QIPGEAMAQKDALSREYEEICNIFLEEGADFFVFETFSEMEELLPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGEAKEIDAVGFNCGVGPSHMHRILQILEKPEGKLLTALP
NAGYPQMVTGRMLFTGDNKDYFVDRMQQMTALGVDMAGGCCGTTPEYIAELAGKLDLTQY
PQAKKDTEPEKKQAPKEDRSFYHTKEAEGRNRKLIAVELAPPMGIDDEKLMDAAHLLQKS
GVDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGI
QNFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFTQAPASYGGAINQGRRNL
EVEIGRVKKKMAAGATFFLTQPISTQESADRVRRIKEETRARILCGIMPFVSLKNATFMK
NEMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVIVMTEDFADGYYFSFPFNRVTMLE
KILN
>A0A4U0H8L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium alkalisoli|TrEMBL
MKIVDHIKNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYLYKQ
HDNGLLERVAYRKRPGTVAICAAIMSKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDSDFIPTPGGHAYATDLLQQVADMNRGQYLHEDIELSEKMNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVDMGAEFIVTQMFYNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSDAVSECKTNADVRQVGEEWLVEQCKELIKFGAPVLH
FYTMSNPGPTKKIVERLF
>A0A4V6I7K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steinernema carpocapsae|TrEMBL
MLKADPLREIRENNRQDYGGTQTALKKSPYLGVQQRAMVLDTTVTIENGFTTGASVKGIA
HANEYVPLHQRIEKHIASGTPFFSLEFFPPKTVNGVANFFTRLDRLREGGPLFVDITWHL
GSDPANKNKETSSTSIASACLDLCRLDTMLHLTCAQYTKQQTLEHLNQCKSLGLRNVFAL
RGDLPKHDNNPVVYQHRALDLIKWIRKEHGDHFSIGASGYPSGHPEAESYQHDLLYLKAK
VDAGAQFVITQLFFDADVFERFVHDCRAIGITVPIIPGIMPIQGYESIRRIADLSNLTIP
DIIMKTLEPIKHDDEAVRNYGTYLATQMCRQILNNGTAPSLHIYTMNREGNCREILQNLG
LWMQQPQRSLPWMPHGGHHPIRCKEDVRPIFWSARPKSYIFRTKDWDQYPNGRWGNSSSP
AFNDLQDYYLFYLKGTPTDDHMLDMYGRQLNSVDDVRKVFVNFITQEENENRVKVTRLPW
NEQESGTLPETTLIQEQLLWCNKNGIFTINSQPAVNGAPSADPIVGWGKPGGYCYQKAYL
EFFIEKAKAEQLKKVIEKEGYSHLSYHMINYNSTVEWTNGDSTTPIAVTWGVFPGCEIAQ
PTVVDPLSFRVWKDEAYDAWLSTWAAIYPEGSISTKILQEVHDNYYLVTVVDNDYVKDTV
IFEALAKAVEP
>A0A1I4AYM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus ruber|TrEMBL
MTRTVRELLAGGRPTWSFEFFPPRTPEGAAGLWTALRELERLHPSFVSVTYGAGGSTREG
TVSVTERIATETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WVAHPQGLRYAAELVELVRSMGDFSVGVAAFPEKHPRSPDYDTDVEMFVQKCRAGADFAI
TQMFFRSEDYLRLRDRVAAAGCDVPIIAGVMPVTNARQIARIVQLSGQAFPAELATRFAA
LDGDRPEDKAAVRAYGVEVATELCRTLLAEGVPGIHFITMNRSTATREVYASLASLAPTS
>A0A4R4N9A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura bangladeshensis|TrEMBL
MGFEVVCEVEPPTRPDLQKVRHQIGVLSPVADSFLIPDNHIGRATVSSVAVAHEVQAMGA
RGIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVYGDKPRAGGRTSELTVRAMMEEARAA
SEDEVFAGCGPFQVGVTSGLRSVPAWKQAADLTFVQVSYSVESLLRWRESAGVDGPVYAG
VMVLASAGMARNLAAAIPDIDIPADLVEAVERDRAAGVAAACEQVLAIRDSGAFDGVHLV
PVSRYREVAARLERDL
>A0A374AD35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF12-5|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPE
AMKQAGIAYATDQIIDLLANGVNNIHIYSMNKPEIAIAIMNNLSEIIKC
>A0A2P7EDW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus lacustris|TrEMBL
MAPGFEQALAGXRPVITAEITPPLGGDPSRALAAAESLRGLVQAFNVTDGSRAVMRMGSL
ALCKLLQERGLEPVLQLGCRDRNRIGLQAELLGAHALGLRNVLCLTGDPVRAGNQPLARP
VFDLESVRLLXQVQALNQGLDPLGKVLPDGPTSLFAGAAADPQSPSWSGLKSRTARKAAA
GARFLQTQMVMDPEALRRFCXEITNPLGLPVLAGVFLLKSAKNASFINRVVPGAQIPQAL
IDRLAAAADPRLEGIRIAAEQVSSYCKIAAGVHLMAIKAEESLVDVLALAEI
>W0DW27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomicrospira aerophila AL3|TrEMBL
MKPTITHLIKHSSIEVTPKGALSVANVADFLQPNTPVYVTALPGMDFADTLHTCKRLANE
GMIPVPHFTARRFKNRAQLELQLATATEECGVTQILALAGADKQPAGAFSDTISMLETGL
FEKYGIQSIGIAAHPEGCPDIAPASLKAHKQRKIQFSEVSEIDMYMVTQFVFEAQPIIDW
IERIREEGNPLAVHVGIPGIASLRSLIGHAQACGIGASKNLLLKQAKNIHKLLSLQAPNK
LIRDLADYTLKTPEAKITGCHLFPLGGFEQTAKWRSAIAKGQFELTADGFELHYCKKCHL
VGNR
>A0A2E0SG06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula sp|TrEMBL
MASVAQFYTADRKGLSFELFPPKTEKGGVSLMRHTEALMQFAPDYITCTYGAGGSTQTKT
MDVITQVKSTFNIPVASHLTCVGSTQDDLRQYLENASQQDIDFLVALRGDPPQGDTEFKA
VAGGFRYANELVEFIRAEFPNFGIAVAGYPEVHQEAPSAEADLENLKRKIDAGADIVITQ
LFYDNKDYFEFCDRCVAAGINIPIVPGILPVTNLNQIQRITSLCGSKLPESFIQRLGEKG
EDNTEWQFEAGVELAIAQVQDLIDSGAPGVHFYVLNKSQATLRVLETAGW
>A0A1Y3P353|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas caspiana|TrEMBL
MSQDRSFSFEFFPTKTEAGHEKLLNVARQIASYNPAFFSCTYGAGGSTRDGTINTVMQLQ
NEIQVPSAPHLSCVGDSKDDLRGLLNQYKEAGIKRIVALRGDLPSGMGVASGELRYASDL
VSFIREETGSHFHIEVAAYPEMHPQARNFDDDVKNFVHKAQAGADSAITQYFFNADSYFH
FLERVQKKGVNLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7H0I8C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces roseirectus|TrEMBL
MTAAPHPLFLDPSVEMTGKDTPALEQAAFAPGTRVNITHLATETLDARVEAARAARDLGL
VPVPHLSARRLRSASELAETLAAFASVGAAAHVFVVAGDPTTPHGPYPDALSVVRSGLLG
QHGVREVGVAGYPEGHPVIGTPALWSALEAKTAALREQGLAGGVITQFGFAVDPVLTWLA
EARRRGVDLPVRVGVPGPAGVRRLLSYARRFGVTTSAGIARKYGFSLTHLMGTAGPDRFL
RALAADLSPQAHGEVALHLYTFGGLAATSHWLTSLGLTAAAAEVPPTPSPRSPAARTTAG
>A0A6A6HWK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trematosphaeria pertusa|TrEMBL
MHVSEMLAQSRAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPKFIDVTWGAGGRLS
HLTSEMIKVAQSVYGLETCMHLTCTDMEKSKLDEALKEAYQAGCTNILALRGDPPREQEK
WEATKGGFRYAKDLVKYIRDRYGNHFDIGVAGYSEGCDDNKNVDQLVDHLKEKVDAGATF
IVTQMFYDTDIFLDWVKKVRAKGIDIPIIPGIMPIHTYAAFLRRANWTKCHIPPHWTEAL
EPVKNDDAEVREVGKGLVADMCRKLIDAGILHLHFYTMNLAQATRMVLEELELLPDVESP
LQKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDARSPAFGELDA
YGIGLKGTNEQNIKLWGSPVSIKDISDLFVRYMEGKLNSLPWSEAPITKEAESLQQDLID
LNRRGFLTINSQPAVNGAKSSHPVYGWGPRNGYVYQKAYLEIFVSPEHIAEVITRIERDP
DLTYYAVNKEGDLKTNAPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYTLGQEW
ANCYSSINPSRYVIEDLMDTWYLINIVHNDFHVEHGIFPLFEGLQVANMEKPLHRTGTPT
PIATNGDAASNGDSGVKDRKPKLDELVDAAKSAASAVTNGLNSLKVSN
>A0A6J6SCF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MERMTVSVEFFPPKDDAGEARLWEASSALESISPDFISVTYGAGGSTRDRTIQITKEITK
RTGRSTVAHLTCVGSTKDELIQILNQYKNAGIKTILALRGDPVGGPTANWVTTPGGFDYS
EQLVELAISQGGFEVGVAAFPDGHPASGGNITKDIDVLIRKEQLGATFATTQFFFESSKW
QNLVTKLEARGSKLPVIAGILPITNVKQLQRMAELNGTPIPETISKAFTGIADDPESVRK
VGIELATKFCEELIALKVPGLHFYTMNNSLATLEICNNLGLTNRG
>A0A6G9AFL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma aureum|TrEMBL
MFLEKIKSGQSGVLLYGITPPKAGTAPERVAEIAQKTMERLSTLDIDALVVYDVQDESAR
TTEERPFPFLNALDPLGFAADYLATLNIPKIIYRPAGKFSNVELSDWLEELHEHNFYPVF
VGVPAPDFPVKTSLPEAYKIWSKHQDTSVIGAVTIPERHNVLKDEDVRMLDKMNCGVSYF
ISQCVFNLDYAKQVIEDLAINCNRQQIKSPTIIFTITACGSTKTLHFMEWLGIHVPDELK
EDLKKSDDILEKSVKICLDIASELTTYCMERSIPFGFNIESVAIRKAEIEASIYLANEIG
QMLHDKGVRKSPESKDFEVTNGYR
>A0A6J6P4V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MDNAHRNPLIELSFEFFPPKDQPGEERLWQELTQLRSLSPKFVSVTYGAGGSTRERTIRV
TEEIGQRTGLDTVAHLTCVGSTQSELSEVLDSYKGAGIKEVLALRGDPVGGPLATWESTP
GGFDHADQLVKLAVEKGLGVGVAAFPDLHPASNGNVELDLETLLRKEEFGATFAISQFFF
EISSWERLMNQLEKAGSNLKLIPGVMPVTNVKQIVKFAQLSGTQIPDKTRTRFEAVAEDE
KAVRELGVEIAAELCTQLLELGCKSLHFYTMNTAEATVKVCQSLDLGK
>A0A6J6SMK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MDRGAGSVASAHHQFAALASSHHRLAALASSRHRPIVTAECPSADGGTIDDLAARLATIA
PFVDAVNVTDNPAAHAHASNVSMAIALAGLGIEPIMQIVCRDKNRLAIQADIAGAAMFGI
VNFSALTGDDVTAGDEPEARRVFDLDGPQLVSVLAGMKAGTYLSGRKFTPTGDFFIGAVE
NPGAPPLDYRADRALLKVNAGAQMLQLQISYRPDQLEAFMSACVANGVAQRAIVLPSVCL
TKGARALSFMNDKVPGISVPAETIDRVANADDQAEEAYHLVRDLTAHALQLPGVAGIHIT
DFRHDGSVQRLTEELRIGPRFDSAIAETGTNPEHEERHAHSS
>A0A6J7VRL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MVVRTSYSLEFFPPKDGEGELRLWSALEELEHIAPEFVSVTYGAGGSTRNRTIGVTEEVT
HRTKIPTVAHLTCVGSSRQELISILHMYRNAGIRGVLALRGDPAGGPRAPWTPTSDGFTH
ADELVQLIHEFGGFDIGVAAFPDGHPSSLGDSKKDVDVLLRKEHLGATFATTQFFFEVAK
WEQLVYALQARGSKMPIIPGILPITNVKQLHRMAELGGTPIPPSVSEAFSKVEDDSDAVH
ALGIELASNLCEDLLRAGAPSLHFYTMNSATATNQIYRNLNNAH
>A0A6J6TM29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MDRGARAVTSAPTRLAGLARSRNQLATLASSRNRPIVTAECPSADGGTIDDLAARLATIA
PFVDAVNVTDNPAAHAHASNVSMAIALAGLGVEPIMQIVCRDKNRLAIQADIAGAAMFGI
VNFSALTGDDVTAGDEPEARRVFDLDGPQLVSVLAGMKAGTYLSGRKFTPTGDFFIGAVE
NPGAPPLDYRADRALLKVNAGAQMVQLQISYRPDQLEAFMSACVANGVAQRAIVLPSVCL
TKGARALSFMNDKVPGISVPAETIDRVANADDQAEEAYLLVRDLTAHALQLPGVAGIHIT
DFRHDGSVQRLTEELRIGPRFDSTIAETGTNPEHEERHAHSS
>A0A6J6F8V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARIADLIAKGRTFSFEFFPPKTDSAQLSLGRAIGELESLGPSFVSVTYGAGGSTRQRTH
AVVSWMRKETTLTPMAHLTCQGHVRSEIRDILNAYADDGVQNILALGGDVPTDGEPAPSD
YTYASELLDDVSGDGRFSVGVAAHPEVHPRSTDRASDRRFLAAKLSRADFAITQFFFEVE
VYVRMMNELADLGVNKPVLPGIMPVTNKKQIVRMAEMSGAAMPQWLIDRLDKVDDPEDVR
RVGVEAATELCRDLLDAGAPGLHFYTMNRSTATREIHANLGLSSAC
>A0A6J6JLR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MAGEDRLWQALSSLATLHPDFVAVTYGAGGGTRDRTIRITSEITARTSIPTVAHLTCVGS
TRDELIEILHRYTESGIKSILALRGDPVGGPRAPWTPVDGGLTHADELITLAREQGDFTI
GVAAFPDGHPNSEGNFDKDIDVLLRKESLGASFATTQFFFEVDKWKRLVDALAKRGSTMP
IIAGVLPVTNVKLLTKMAELGGTPIPDSIASRFAAVEDNPEDVRKLGVEIALNLCNDLID
AGVPGIHFYTMNSSTATSEIFESLQDRR
>A0A6J7XWG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSKLSDLLENTTELVYTAEFPAIDGGGMAQVQKYVDRLSPWFVAVNSTDNTAAHAHASNL
SVAIAMNDRGLEPIMQIVCRDKNRLAVQADMAGANLHGIHNIALLTGDDVTAGDEPETRR
VFDLDGPQAINVASVLNAGTYLSGRKLNPPPNFYISAVENPYAPPHNYRIERALKKQRAG
ARMLQLQIGYHPDRLENFCRGVAQSAPGLHLIPSIVLVKSARPLNFMNDKVPGIDVPRDV
IESVEKAEDQSEAAYQLALEQCKHALSLPAVRGLHITDFRHDDTLERLMNDLGRTPNQYA
>A0A8I0GKK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas balearica|TrEMBL
MSTSHRPSISFEFFPTKTDAGHEKLLATARQLAAQQPDFFSCTYGAGGSTRDRTLNTVLQ
LDSEVKVPTAPHLSCVGDSKTELRGLLNLYRDAGIRRIVALRGDLPSGMGLASGELRFAN
ELVEFIRSETGDHFHIEVAAYPEMHPQARNFEDDLSNFARKAQAGADSAITQYFFNADCY
FYFVERVRKLGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIESIQA
FGEQVIAQMCEKLLAGGAPGLHFYTLNQAEPSLAICSALGLSR
>A0A3A4QYA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriales bacterium|TrEMBL
MKVIEHLAKAKHTLISFEIIPPKRGGDIKALMEVLDAIIKFNPPFIDITSHAAEVIYEET
PSGGYKMKIKRKRPGTLGICALIQNKYNVDAVPHVICHGFTREETEDFLIELHYLGIDNV
LAIRGDDSGYHKPVKFGRSINQYAIDLVKQIKDINSGKYIEDSLLDAEPMNFCIGVGGYP
EKHFEAPNLAIDIKYTKQKVDAGADYVVTQMFYDNKNYFQYLEKCKEAGITVPIIPGLKI
VTSKQQLQSLPKHFYIDLPNELTEEIDKAKPEHVLEIGVNWTAKQVEELLNENVPAIHFY
IMQNPKPINMLMKKLKL
>A0A1F9BXU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_50_11|TrEMBL
MSFKECLDSGKFSVIVEFQPPKGNDLSELYENAELLRGRVDAVNVPDLQNAIMRLGSLSV
CSLLKTKGMEVIYNLSCSARNRLALQSELLNASALGMTNVLLLHGEHPSIGDHFEAQPCF
DLDVMGLLGTAKRLQEGYDLMGNDLQGKPRFCVGTLVNASSKGHVLDLELMDMEKKIRLG
VDFFVTNSIYDVSVFEPFAKKVAHFKVPIIVGITLLKSVGMARYVNKHVEGSFIPDAIID
QLVKGSDKQKASTEIAGHLIRELKPLCQGIQIIPIGWEKQIPALLDQAGL
>A0A1I6B8I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Siccationidurans arizonensis|TrEMBL
MKVTEHLERADGKTLFSFEVLPPKKGENIHTLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFTKEETENALIDLHFLGIDS
VLALRGDPIKSEGVFKPEPDGHAYAADLIGQVANLNKGEYLDQEQDDVWATNFCIGTAGY
PEKHFEAPNYNSDIRYLRHKVDRGADYIVTQMFFDNEEFFRFERLCREAGINVPIIPGLK
PLTTKSQLTMLPRAFYLNLPETLVEAVSQCRDNDAVRTVGIEWCLNQSRELMAHGVPCLH
YYSMGKSESIRRVAKELF
>A0A401UZE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas algicola|TrEMBL
MSAPVVDAVPGTVDATGTVADAGSRRTTGPHVVPDRPLAAIDRPTVSFELFPPRNPDAAP
RLWETIQRLGEAHPDFVSVTYGASGRTRVTTRALVSRLLRETSLNPIAHLTCVGTSRDEI
TAIVEEFLDEGARSFLALRGDPPAGQDDWQPHPDGVNTASELVELLREIESRRCAGSPSQ
AVRARVRPLSVAVAAFPRGNAATGGTRAQDVASLLAKQEAGADFAITQVFFDAESYLGLV
AEAHDAGVTIPIIPGIIPSTDPARLLRVQDLTGVPVPRDLLDLLGSADDDLERHRRGIRA
GVDLVQGVLDGGAPGVHLYTFNQHHAALDLLEGAGLDGGARTGRSAVPVTAPTATTPGTP
GPTTTAPDPTHEGQTPR
>A0A2U8X9S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. 17Sr1-1|TrEMBL
MEATLWSSIERLAPLGPSFVSVTYGAGGSTRERTHNTVSRLVRETDLKPAAHLTCVAATK
GEVDDVVRAYHEAGVRHIVALRGDPAEGVGTAYTAHPGGYERSCDLVAGIKRIGDFEVSV
SAYPERHPEAGSLDQDLDALKAKVDCGADRAITQFFFDNDLFFRYLDRVQSRGIDIPIIP
GILPVQNFKQAANFARRTGASVPDWLAARFEGLEDDVATRKLVAAAVAAEQVLDLVDRGV
TDFHFYTMNRADLVYAICHLLGLRAAPAAAEKAAA
>A0A434DTM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.T.Ca.TU.009.01.3.2|TrEMBL
MIGRQIDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRSYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A1I0X185|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides alpinus|TrEMBL
MTHGRDLSMGELLARGERSFSFEFFPPKDEAGEEQLWQAITELEPYGPTFVSVTYGAGGT
TRDRTVAITERIARDTTMLPVAHLTCVGHTTDELTAILDELDAAGVHNVMALRGDPPDGP
GSPWTPTEGGLTYANELVALIRERTDMRIGVAAFPEGHVDAADLETDARVLKAKYDAGAE
FAVTDMVLRASDYVALVERATAAGADFPIIPGIMPILNLRSMQRMVEFSRRELPEEITAR
LTPYADDAVRLRAEGIAIATELCEALLDAGAPGLHFYTLNRSRATREIFANLRITV
>A0A0S4HVZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. URMO17WK12:I11|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKANAGANSAITQYFFNADSYFY
FVERVRAAGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>I4CNC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri CCUG 29243|TrEMBL
MTALNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLTNFVRKARAGADSAITQYFFNADCY
FYFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQA
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>L7EW58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces turgidiscabies Car8|TrEMBL
MTTQREDAVSRRRRTHLVDLVRNISYEVMPFKNTERDVLHSVPTEVPLTVTVTEAKGIDA
TLDLTERLKRHGYAVSPHLPARQFVDKEHVADVMARLKESQIESVFVVGGDAPKPAGAFP
DAFGLLRAMEEMGHPFGTVGIGGYPEGHPAIPQEALELALQQKAPLASRILTQICFDATT
TANWAAGVAGTGVGLPVYVGMPGPVNRQKLMRISAGIGLGQSARFLQKQQSLLWRFLLPG
GYNPTKLAKKLGAAVSQSDGNIRGLHIFTFNELRQTELWRQRLLSAVSAQTSERDDWS
>A0A318HGL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerotilus hippei|TrEMBL
MTFTAASDAALPLSLEFFPPKTPEGALKLAATRQELYALSPQFCSVTYGAGGSTQDGTLS
TVQAILDEGQAGASHFTCVGATRESVRDRLAQFRAMGMRRIVALRGDLPSGYGQMGEFRY
ASDLVAFIRAETGDHFHIEVAAYPEMHPQARSPQADLQAYAAKVRAGADSAITQFFFNSD
AYFRFVDDALALGVDIPVVPGIMPITNSSGILRFADSCGAEIPRWMRLRLQGFGDDSASI
KAFGLEVVTDLCDQLRTAGVPALHFYTMNSSATVLEICRRLKWSA
>A0A668UN34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oreochromis aureus|TrEMBL
MVNQVQRGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQSKEKITGYLAKAKHLGLKNIMALRGDPVGEDWEEEEDGFNYAID
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNY
GIQQAVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELQNEESVFEVFTSYITAQPNHCGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVNGRNLTNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWGK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPELHSEETV
>A0A8E2JP97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glonium stellatum|TrEMBL
MHISQKLEQSRRENRATFSFEFFPPKTAQGVQNLYDRMDRMHDFGPSFIDITWGAGGRLS
HLTCEMVKVAQSVYGLETCMHLTCTDMGKPKIDAALKEAYKSGCTNILALRGDPPREKEK
WEATAGGFRYAKDLVKYIRDTYGNHFDIGVAGYSEGCEDQEDSDLLIDHLKEKVDAGATF
IVTQMFYDVDIFLNWVDKVRAKGITIPIIPGIMPIHTYAAFMRRATWTKCHVPPAWIEAL
EPIKNDDVEVREVGKGLVAEMCRRLINAGILHLHFYTMNLAQATRMVLEELGLTPDMETP
LEKPLPWRPSLALGRREENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDARSPAFGELDA
YGVGLKGTNEQNIKLWGKPVSIKDIADVFVRYMNGKLNSLPWSESPISKEADTIQEDLVD
LNRRGFFTINSQPAVDGAKSSHPVHGWGPRNGYVYQKAYLEVLISPEYIAEVITRIERDP
DITYYAVNKAGDLKTNAPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQDW
ANCYPSSSPSRYVIEDLIDTWYLVNIVHNDFRVPHGIFPLFNGLQVEDMEKPLHTVGIVN
GNEASNGDHSAENPAVNGAAAHTNGTVHTITDGVNGVELKN
>A0A433QQU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jimgerdemannia flammicorona|TrEMBL
MKVIDKINKAIKENQPCWSFEFFPPKTPQGVQNLYDRMERMYGMGPEFIDITWNAGGVTS
DLTAEIVTTAQSVYGLETMMHLTCTNMPKEKIDIALREAKACGCRNILALRGDPPRGQTE
WQACDNGFEHAIDLIKYIKEQYGDWFGIAVAGHPEGHVDNRDLEEDILFLKEKVDAGADL
IITQLFMDTDIFLQFVDRARRVGITVPILPAMFAIQSYNFLKRVTSFDNNHVPQQIWDDL
EPIKHDDEAVKAYGVDLSVRMVRELYAKGFRAFHFLTFNLAKSTRLTLEKLGWVPSLEMV
KPLPWKPETVRPIFWKNRTHSYVQRTENWDEYPNGRWGDARSPAFGEIDGYGVTLNFTPE
ECLTMWSRPTTISEICSLFARYCMGELKALPWSAQQLELESDSIRQRLTEVNLAGYLTIN
SQPAVNGARSTNPVYGWGPVNGYVYQKAYLEFFVPKEMLTALEEKIAKDGDITYFAVNIK
GDLKSNSGKEKSPTAVTWGVFPGKEIVQPTIVEEDSFMAWKVWFRRPIRFAVMVTT
>A0A530R1G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
FVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILCGVGPLASAKTAKWIRSNVPGIHIPDSI
VKRLEGAHDQKKEGKQLCIDIINEVKEIPGVSGVHVMAYRQEEYVAEIVDESGVLKGRQP
WKREIRRDDQLVADRLDHILHDEITETQVDMVKTAH
>A0A4R4HKE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. 204|TrEMBL
MSTQQHPLGISFEFFPPNTAAGREKLVGVRDALAERGPRFFSVTYGAGGSTQDRTLTTVR
QVREAGITTAPHLSCIGSEKGQLRELLARYREEGIDSLVALRGDLPSGMGGVGEFRYANE
LVEFIREESGDHFEIAVAAYPESHPQAPSLEQDVENFARKVKAGANLAITQYFFNADAYF
HFVERAQALGVDTPIIPGIMPITNYTKLARFSDACGAEIPRWMRKQLEAYGDDSESIAAF
GEEVISRLCQRLLDGGAPGLHFYTLNQAAPCLKIVDNIVG
>A0A139K3X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides uniformis|TrEMBL
MQDFCQSDKDNEREMRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYI
NITTHRSEYVYKDLGNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETE
YVLLDLQFLGITDLLVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMK
VTNTPFSYGVACYPEKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERAR
QAGVTIPIIPGIKPFKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQ
CKELIAHGVPSLHFYSVGATDSIKEVAKQIY
>A0A3S3C4I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVVREFADMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKSAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHEAEAA
G
>A0A3D5PUW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dialister sp|TrEMBL
MSTLKEKHNQHIFTITTELDPPKSASSSVTEAQVVKVAPYVDAVNIADCPMAKMRMSPIA
LSSIIQSRYQVESIFHLTCRDRNVIGLQAELLGAYALGVHNILTLTGDPPSIGDHPDAKG
VFEVDSTGLIEIAKALNEGHDIMGHELGEAADFYIGTTANPGADDLDKEIQRLEGKKKAG
AQFIQTQPIYDIRQAENFLAAAKDLSLPILFGIVPLKSFKMANYLNSHVPGIFIPPAVMK
AMETGGRETGIALSRELVQALRDIHADGAHLMPVNDVDAVAEICRTNK
>A0A2I0FQN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacterales bacterium CwR94|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASREELRTIAQDYWNNGIRHIVALRGD
LPPNSGKPDMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMTQMFE
GLDNDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPNVVS
>A0A530N7N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
QYCFDVPMFKTFMQKARDLGHTEKVFILCGVGPLASAKTAKWIRSNVPGIHIPDAIIKRL
EGAQDQKKEGKQLCIDIINEVKEIPGVAGVHVMAYRQEEYVAEIVDESGVLKGRQPWKRE
IRRDDQLVAERLDHILHDEITETQVDMVKTAH
>A0A3M2V7F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. atrofaciens|TrEMBL
MEASSPMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLN
TVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGEL
RHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFN
ADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQ
SIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A4R0YLT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella soli|TrEMBL
MPSISFEFFPPKTDEQRAQLDRVAALLKPLAPEYVSVTFGAGGSTLSYTSETVHRLHRRH
GLNVAPHLSCVGGTRAELAELLDSYRAAGYQRIVALRGDLPSGMASPGDFRYAAELVAFI
RQHSGDYFHIEVAAYPEIHPQADDALADLRHFKSKVDAGANGAITQYFFNADAYFRFVDD
ARRLGVDIPIVPGIMPISNFTQLKRFSDGCGAEIPRWIAKRMQAHGDDAESIRELGADVV
AQLCRRLLEGGAPGLHFYTLNRAKATQSILDRLHG
>A0A529MEH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
VGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAGI
HVMAYRQEEYVAEIVDESGVLKGRQPWQREIRRDDQIVAERLDHILHDELTETQVDMVKT
AH
>A0A2T0FUY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus anginosus|TrEMBL
MLSPSLSFEVFPPNPAVGNEKIMVTLKETQDLAPHFISVTASNNKFNIEEMADFICNGLH
IPTIAHLPAVYLTKEMVTETLTALDKIGVHKVLALRGDILPDVESQKDFVYATDLIEYIK
KEAPHFEIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYDFQDKCI
LAGIEVPIHAGIMPILNRNQVLCLLKTCENIYLPRNFCSILDKYEHDPESLRAAGLAYAI
DQIVDLVTQDVAGVHLYTMNNSSTAHQIYQATHTFFDK
>A0A527XHA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
PQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAAAGSAA
A
>A0A659YR67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
YIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFDGLQKDPQTHALVASAVAAEQVLD
LVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAAGSAAA
>A0A659YIR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFAGMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYI
>A0A4R7J6F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naumannella halotolerans|TrEMBL
MSVNTRPATIAQLLEASDRPLFSFEFFPPRDAEAEQTLWRTVRELEPLGPDFISVTYGAS
GSTRDRTIRSTERISRDTSLRTMAHLTCVGQSAAQVRHTVGAYAAAGVHHVLAIRGDPPG
GPTAPWQQHPEGLANATELVELVASLGDFCIGVAAFPDLHPDRRDAELDARILVAKAAAG
ASFAITQLFFDPQAWLRLVERVRARGCDLPIIPGIQPVTNLRQIERFAELSGADLPRRVT
DRLNAAGDNPDAVRAVGIDIATELCEDLLSLGAPGLHLYTLNRSRASREIFARLH
>A0A3R7WSY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium TMED194|TrEMBL
MKSKLRKSLNDNKFVFTAETSPPDSGSKIDVIDQVKSLKGLADAINVTDGAGANSHMSAL
ATAAIIAEDGIEPILQFTTRDRNRIAIQGDLLGGWALNIPNILCLYGDEVKSGDQPEAKE
VRDLDTISLLKTANNIKVNKNYPSGRRIANAPDFFIGGADTPFKINDDFDGANLFKKIDV
GVEFFQTQYAFDELILQKYMKKLNQLGIISKVYFIVGLGIIKSAKSARWMNANLFGINIP
DDIIKRIDKSENEKAEGKKICIELIQKYKSIEGVSGIHLMGYKQEEDIASVISHFQ
>D8EZP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|delta proteobacterium NaphS2|TrEMBL
MNHESQLKKVLSQGEFAVTAECGPPKGADPDVILKKGELLKGSVDGVNVTDNQTAIVRMS
SLAACSLLKTAGLDPVLQMVVRDRNRISLQSDILGASALGIRNVLCLSGDHQIFGNQPQA
VGVFDLDSIQFVQVVKGMRDDGVITGGDSLDHKPDMFIGAAANPFADPLNFRIVRLAKKI
KAGADFIQTQCIYNLDRFESWLSMAADRGLTEKAYILGGVTPLKSAGMARYMKNRVAGMD
IPDDVIKRMEGVPKEKQREEGINICVETVSRLKELPDVKGVHIMAIEWEEAVGEIVKQAG
LHPRPLQDKG
>A0A1M6ZJ75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas punonensis|TrEMBL
MSQKRANVSFEFFPTKTDAGHEKLLNTARELAGYNPDFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDSKAELIELLNLYKSKGINRIVALRGDLPSGMGMSSGELRHAND
LVELIRQETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGASSAITQYFFNPDCYF
YFVERVRKMGVDIPVIPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDTQSIQRF
GEEMITDMCRRLLDGGAPSLHFYTLNQAAPSLAVWKNLQG
>E8WQT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp. (strain M18)|TrEMBL
MKGTFLERIAAGVLIGDGAIGTMLYAKGVAPEANFEHLNLVRPELVLELHREYLAAGAQV
IETNTFGANYAKLSAIGLGAKVAEINRKGAQLAKSAAAGRDVFVAGSIGPLGRGKSELTG
EQAADCFRVQSAALAEGGVDLLILETFSELDELLTALAAARETGLPVVASLAFGEGGRLP
GGILAESAAQRLAAAGADLVGANCGAGPLELLATVRRISAACPLPLAAYPNSGFPEYLDG
RYIYRTTPEYFADRAEELIAAGASLVGGCCGTTPEHIKVMAQRLQGRKPAARVAVSVAGS
ALEEERGEKVQVGFLDRWGTEPVITVELDPPKGLDCARVLAGSRALKDAGAHAINLAENP
LARVRMGNLALASLIRREVGIEVIAHVTCRDRNLIGMQSELMGASLLGVSSILAVTGDPA
SLGDEAGASSVFDLNSFTLIKLLSDLNRGVNALGNPIGAGTGFAIGAAFNPNTQKMEVQV
GRLARKVANGARFAQTQPIYDLERFEQMMEQTAHLGIPILPGVLPLVSGRNAEFLHNEVP
GIVIPEGIRARMAGKTGEEGVAEGLAIAKEFIEAAGAKAGGFYLIPPFGKYEIAVELVQF
IKSLRRPLP
>A0A7V0WXI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIEYLQKAKDPLISFEIIPPDRGRSAEPIYRIVEELLEFKPPFIDVTSHAADASYVQQ
PDGSYIRKINRKRPGTIGLSAAIKYRYKIETVVHLLCSGFTREETEDALIELSYLGITNV
MALRGDEHNYRKTVQPNRTVNPSAVNLVEQISRMNRGIFLDDELPADPTDFCIGVAGYPE
KHAEAPSLAADIRFLQQKVDAGADYIVTQMVFDNRRYFEFVDRCRAAGITVPIIPGIKLL
TARRQLNSLPRIFNISLPDALVQDVLAAENDAAVKEIGIAFARKQVEELLNARVPCIHFY
VMQQATRVKQVLGSLGL
>A0A660XIB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MESFGTYIKNHVLLFDGAMGTFIYQKGIFIDKCYDELNLSNPELIRSIHDEYLKAGAEAI
ETNTFGANRYKLARHNLAGKVKIINRKGARIAKEIAGSRAYVAGSMGPLGVKIEPWGETS
FEEANEVFREQAQALLDGGVDLFILETFHDIREIEEAVKAIRSISDFPIIAQMTVQEDGK
TSYGIELKEITERLSSSEADVIGLNCTVGPKHMLDFLEQMVKITTKPISIIPNAGKPQYV
DGRTFYMSTPEYFCVYAKRFIETGARIIGGCCGTTPEHIRKMAEALVQKQPRIVIQKKTK
LEPEVEVSLPEPVPTKQKSKLAEKIVQGKFVTLVEMLSPRGRDVTKQLAGAKKLKEKGID
AVNIPDGPRASARMNGLALAILLQNHVGMRLCFIIRAGTEVL
>A0A8J4WNG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Udaeobacter sp|TrEMBL
MHITDIMRGDSPTFSFEFFPPKTTEAVETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIERILLRYAKSAIGNILALGGDRPVGIAYDKSR
DSFQHAIDLVKFIRRFNESGTHPDRRGFGIGVAGFPEGHPATPNRLFEMDYFKAKVDAGA
DYVVTQLFFDNRDFLDFRERCTLANIQIPIIAGIMPVTSIGGFKRIAELAGGARFPAKLL
RALQRCQSDPEMVKRVGLHFAIEQCHDLLDNDVAGIHFYTLNRSDATRVIFDSLGIPRRR
NPEPSSV
>A0A7C7MWQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEKIADYIAEEKTFYSFEFFPPKTDFGMDNLYSRIDRMASLHPAYIDVTWGAGGSTA
DKTLEICKTIQKYFGLEVMMHLTCTNMAVSSIKKILTEAKESSLFNILALRGDPPEGSLT
WEKHADGFRNGVDLVRYIRKEFGNDFFLGVGGYPDGHQEQTDIDIDINFLKEKVDAGSDI
VVTQLFYDVDKFLLFRDKCIKAGIKVPIIPGIMPIHNYGRFLKFTQFCELSIPDSVSTQL
ESIKNDDSSVINFGIDQATTMCKKLIEEGVPGLHFYTLNLEHSVSEILKSLDLVSSRGIS
KELPWRQSTLGDRKTSEDVRPIYWSNRPVSYLTRTESWDDFPNGRWGDITSPTFGELNQY
HAIRAGAKSDKVKARRKKIWGEPKSIKDIKDVFVSFCKGKINSLPWCEMQLAQESQQISS
NLINLNEMGFFTINSQPNVNGAPSEDAVVGWGGAGGRVYQKAYLEFFTSKDKLNALLKSI
KSTENISYQAINIDGDLITNLPENSVMAVTWGVFPGKEIMQPTIVDTRSFLIWKDEAFGL
WMSDWASIYEEKSASFKLLKEIYETYYLVNIVDNNYVDSNLLKKLLNYEKA
>A0A3R6ZH00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces astaci|TrEMBL
MGKIIDRLTELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPREQLREILKNVRAAGIRNILALRGDPPIGSE
RWKAIPGGFQNAVELIRFIREEHGDWFCIAAAGYAEVHTEAWNNPNLPPSDQARRVDMLR
LKEKQDAGADFIITQFFFDVDKLLQWIRDCRQVGITIPILPGYLPIQTYNSFLKFTNWCK
TSVPPQVEDALVTIKNDDSAVKKYGIQLAVDTCRKLLANNLSLHFYTITIIRENLRWINS
MGFLTINSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPHLMQRLVYVWLLLLING
EIGTEYTNSPGPSVTAVTWGVFPGKEIIQPTVVDTASFAAWKDEAFELWLSQLVLMGSNN
VEDSDIFKIFARVITESMTKDDLRQRVLELEGKNEKLHETVAKLKIIQADANRELKDLHG
DLSTSREENSRLKAQVRELRSRLAMAEL
>A0A800FJG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISDKLEDFKAQGKTYYSFEFFPPKTDFGLDNLYTRIDRMASLQPAYIDITWGAGGSTA
ERTLEMSKTIQKYFGLEVMMHLTCTNMSVSSINKVLMDAQENGLSNILALRGDPPEGTGE
WEKHEQGFKYGIDLVRFIRKEFGDDFFLGVGGYPDSHQEQSDIDKDISYLKEKVDAGSDI
VVTQLFYDVDKFLVFRDKCATIGIHVPIIPGIMPIHNYARFIKFTQFC
>Q8X766|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O157:H7|TrEMBL
MNFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7J4ZZD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. AMSO12t|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGDPGGDWVRHPEGVLYAEDLVRLVRDAGDFSVGVAAFPYKHPRSTDVDSDTEHFVR
KCRAGADFAITQMFFDADDYLRLRDRVAATGCDTPILAGVMPVTQIGTIERSTQLSGAPF
PPALAERFAKVADDPEAVRRLGVEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLQ
VDARV
>A0A3G2JPK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces dangxiongensis|TrEMBL
MALGTASTRTDRARTVRDMLATGKTVYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAACDTPVIPEILPVTSVKMLERLPKLSNARF
PDALKERILTARDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A3Q9S7P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AWRP|TrEMBL
MSLLKEAFEKGEFAITAEMAPPKGTDLSHLIECAKKIKGRVQGVNVTDFQSATLKATSLA
TCKVLKDAGLEPVFQITGRDRNRIAIQGELLSAGVFGIENVLALTGDYTATGDHPGAKPV
YDLDSVGILQVASILNGGKDMGGTDLKGKPDFFLGACVTPRYDPLELQVIKMKKKIKAGA
KFFQTQAVYDMETLKKFKEETKAQGVDAKVMVGIIPLKSAGMAKYMNKNVPGIFVPDELI
DRMKNAEDKVQEGIKIAGEFIKTVKESGLCDGVHIMAIGAEENVPLILDEAGL
>F7L2F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. animalis 11_3_2|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSLEKPDYISVTYGAGGNTKGKTV
EIADRIKRQNGVESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEKGD
FNYARELIEYIHKKKGDKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRHE
>A0A4R3X887|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGEHFHVEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERIRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A240CGV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia ficaria|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASPAQLRDIATDYWNSGIRHIVALRGD
LPPGGGKPEMYATDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A202FXA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clavispora lusitaniae|TrEMBL
MKITDKLQQAHSCKVGGSAPPATFSFEFFVPKTSQGLQNLYDRMDRMYDLNPIFIDITWN
AGGRSSTLTNEMVYTAQSTLGLETCMHLTCTNMPVSLIDEALEKAFKSGCQNILALRGDP
PLDGSESTGDFKYAKDLIVYIRKRYGDHFNIGVAAYPEGHPEEQNSPNLLKYLKEKVDAG
ADFIITQMFYDVDNFIAWCAKLRELGITIPIIPGIMPISTYSAFIRRANWSQVAIPQHFL
DALNPIKEDDYAIREVGTQLVSEMCQKLIDSGYVNHLHFYTMNLERSTVMILEKLNLVES
IKDNDAVVEILPWRKSLNPSRSKESIRPIFWQNRKYSYISRTSGWDEFPNGRWGDSRSPA
FGDIDLSASELLRQSPKRAYELWGCPQTLNDLSDIIVSYLNNEVKALPWSDGPIGEDTTV
LKDALIALNRKGLFTLNSQPALSAVRSNDKLYGWGPKNGFVYQKQYLEFLVRKDKLKELL
DIVEKHNAKDTYGLITYYAVDKSGNLHTNSKNDDINAVTWGVFPGEEILQPTIVEKVSFL
AWKDEVYSLLDEWITIFHSKAITDIVPEDKINKFDDLIKSFGENFVLCNFVNNDFTSDNN
VMFNLLNSLSGSCL
>A0A3G9H9L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenimonas sp|TrEMBL
MFEQLIEKLQDPKAEYITLETTPRHDASFTPVIDTIEKLGIAEYVDGFSTTDNPLAKLKF
NSIIAAMQLQERFKKPVLATMSMRDRNKIALQSDLLGANSIDVRAVLALTGDPAKISDQP
ASKGVFEADSTMLLDIIKCFNAGIDYAGREFGIKPRPIYPFAVSNAFAKNPKTLLKKFTK
KLEHGALGIITQPVFDTENALKLLELFEEAKDLSGNGKGVLILGLFPVTKLRTAQFLASH
VPGIDVPKKWIDELYEAHRKGEEEEEKRGLALSSAIFESVREIHPKIHLMTANRFTLAKK
LLRSRS
>A0A1M6NRG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionispora hippei DSM 15287|TrEMBL
MYIRDLFYQRRKPVVSLEIFPPKPTLPLESVYATLEGLKELHPSFISVTYGAGGSNSART
IEIADKVKNHYGIEVLAHLTCVGLTREQITATLDKLAACQVDNILALRGDPPQGETAFVQ
PENGYRYAAQLVKHIKETGRFCIAAAAYPEGHIECRDMARNIEYLKYKAEQGADFLISQL
FFDNDSYYYFREQMERAGIQCPMSIGIMPVLNAAQIERITALCGAQIPAALQKLLDRYRN
SAEDMEKAGIEYACEQIADLQKTRFEGIHIYTMNKVAQVKSILQNTGLLTES
>A0A355XPN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEKIANYKALGKTFYSFEFFPPKTDFGLDNLYSRIDRMASFHPAYIDITWGAGGATA
DKTLEISKTINKYFGLEVMMHLTCTNM
>A0A4Z0N217|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium sp. CH28|TrEMBL
MLLRVSSTASAGGQPTSVVDRIRLAERDRVPFSVEFYPPRDEAAEARLWRAARFFEPLSP
AFVSVTYGAGGSTRDRTIRVVGQLAGETTLLPVAHLTAVGHSVAELRALVGAFADRGITN
LLVLRGDPQGGVHNEWVKHPDGLEYAVELVELVRSLGDFRVGVASFPEGHPRAIDLEHDT
ANLVAKLRAGAQYSITQMFFDVEDYLRLRDRVVAADPEQGAKPIIPGLMPITSLSTVRRQ
VELSGSQIPAGVLDRLTTAAGDGAVENRDEVRKVGIELATVMSQRLIDEGAPCLHFCTLN
FARATSEVLANLGMAVSV
>A0A7Z2MCW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. S49|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A7G1NAU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces tuirus|TrEMBL
MALGTASIRSDHARTVRDMLAAGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFQPEDYLRLRDRVSAAGCDTPIIPEVMPIASVKTLERIGSLTNAAF
PPALKERILTAQHDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHSSQA
>A0A7V4XTP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacterium capsulatum|TrEMBL
MNNRLKDIFGDRPVLCDGAMGTSLYARGIFINRCFDELNLSQPELVRSVHEDYLQAGAEI
IETNTFGANAIRLRRYGLQDKVAEINQAGARIARAAVAQLADKQAGNAWVAGSVGPLGVR
LEPLGKVGLDEAQAIFAEQMEGLVTGGVDLLVIETMPALNEAQQAIRAARAVAPELPVIA
MVTVDEESRCLDGTAPEVAAARLASWGADAVGVNCSTGPAAVLTAIECMAEATDLPLAAM
PNAGMPRAVDGRNIYLCSPEYMASFARKFHKAGVQFLGGCCGTTPNHIRAMKSFLRASEA
QKAAVQHSRSAPIVTETPPAPIEQRSRLGQMIHDGTFVTMVEIVPPRGIDCQKEIDGATM
LAGLGVHVINVPDSPRASARMSAQSLCIQLQQKSGIETLLHYTCRDRNVLSIQSDLLGAS
SIGLRNILCLTGDPPKLGNYPDATAVFDVDAIGLVNIVRRLNHGLDIGGNPIGASTGFTI
GCAANPGVPDIDNEVRRFAYKVEAGAEYAITQPVFDLRILESFLKRIEGFRIPVIAGIWP
LTSLRNAEFMRNDLRVSVPDSILLRMQQAATPELARAEGIRIAQEMLETARPMVEGVQVS
APFGRYTAAAEVLAGILPGTSKSDKAQPASQGIQIGQL
>A0A1C5PGZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MRLLDKIKDHILLMDGAMGTYYNQQYGTELEAEEANLVHPEEITAIHKAYIEAGAELIRT
NTFAVNHLMFPKQEECKRAIHAAIACARQAVAESSREVEIAASIGPIRQTVTEDDENTIK
EYQFLINSMLAEGIRIFVFETMLELKWVQPLSEYCKSQCEESVVIVQFSLNPSGYTQYGF
GMKEIIDKLGQMETVDVFGFNCGVGAAHLRKLLEKQTFPKECMLSVLPNAGYQQELRGRM
HYGDDPEYYAKQMERMIPLGINIAGGCCGTTPEHIAALKKVLGGQAPQPKEVVEENADGE
SVSNAAPTDFISKLERGEKVFVVELDAPFDAQMDKFSKGVYALKENGVDMITVSDSPLAR
SRADAALLAVYAKRLTDISVMPHVAMRDRNLIGLRSEILGAHANGIRDFLVITGDPVGLD
NRGKITGVFDVNSIRFMEYLQHMNEEIFPDQPVYYGGALNYAGNNIRAIAGRMRKKMEAG
CAYFLTQPIFSEEDVQRVIELKEMTGAKIICGLMPLVSYRNALFMKNEMPGIHVNDEILN
RYDPEMSREEAEDTAVALCLDIAEALRGAADGFYLMTPFHRVGLVNRIINAIKQGE
>A0A6M0B6M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO3I6|TrEMBL
MTNPTKNSFRTAVESGEFLITAEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQQGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFEK
KLEAGAEFFQSQLICDFDRLEKFMDQIAAGTNKPILAGIFLLKSAKNAKFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSAINDLVCK
>A0A8J3CLB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Formosimonas limnophila|TrEMBL
MSLNIPVSFEFFPPKTPEGEEKLMNTVKALSAYKPEFFSCTYGAGGSTQNGTFTTIANIR
AQGFDAAPHLSCVGATHDYILEVLNDLKTQGVRRIVALRGDLPSGMGGMGEFHYASELVA
FIRERTGDHFHIEVAAYPEYHPQSRSPVDDMKHFVQKMNAGANSAITQYFYNADAYARFV
DDARKAGVTAPIVPGIMPITNYSQLARFSDVCGAELPRWIRLKLASFGDDKAAITLFGQE
VVAQLCERLIELGAPALHFYTLNQSKPSVDVLSALN
>Q3B067|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. (strain CC9902)|TrEMBL
MKTALQCAIEAGKQALTAEVMPPRGADPAHMLAMAAHLQGRVHALNVTDGSRAVMRMSSV
AACKLLIEAGAEPVLQLACRDRNRIALQADLLGAHALGIRNLLCLTGDPVRSGDQPSVRP
VNELESVKLLQQVEALNRGEDPVKGSLPDGATALFPGCAADPHSRSWSGLQRRLQRKAGA
GARFVQTQMVMDPQVLDRFQRELAGPLQLPVLAGVFLLKSAKNALFINRVVPGACIPEHL
IERLEGASNPAMEGVSIAAEQVRQYLGIVQGVHLMAIKAEERIPLILDQANISSPTT
>A0A532DZQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSKEPRRLSEVLSSGQFAVTIEYNPPKGTNISKVLESAKELVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGRDMAGNKLDGSTAFTIGAAVTPEADPVGPMLAKFEVKV
KAGAQFFQTQAIYNPDLFASFMKVVRPYKVKVLAGILLLRNHKMAEFMNANIPGVSVPQE
MIDELKAAGDKAEDVGVEIAVRTINAVRAHCDGVHIMAIKGTHRLADIITKAHIG
>A0A1C5MAN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKKRVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNLYIAEKICEAVKSLF
>A0A1I1AH78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis marina|TrEMBL
MSDMTTVVERLRGDATVFSVEFFPPRDAADEAILWRSIRELESFDPAYMSITYGAGGSSR
DGTIRSIARVATETTLVPMAHLTAVGHSVAELRHVIGSYAAVGVRNILALRGDPPGDPYG
EWVPHPNGLNYAEELVTLVRSLGDFCVGVSAFPYGHPRSADLDTDTLHLVRKFRAGADFA
IAQLFFQPEDFLRLRDRVAAAGCEALLIPGIMPLTTPRTLRKTIELSGASAPSSLLNRLE
PLSDDPKAFRAEGLDAVTELCERLIAEGVPDLHFYTFNRSKATRELVSRLGLVPARA
>A0A1C6GL96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MKIIDRLREDGIHISFEIFPPKTDAGYDKVIRAAEEMAGLKPEFISVTYGAGGGTSKNTA
KIASYIKHDLHVESLAHLTCASSTKDEVRSVIASLKEQGIENILALRGDISEDMVFPSED
RFHYAYQLVEEIRRHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSARQMKRSCELSGTVFPRRFQAILDRFGDSPK
AMEQAGIAYATDQIIDLLANGVKNIHIYSMNRPEVAAAIMHNISEIIQC
>A0A2D0IDX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Curvibacter sp. PD_MW3|TrEMBL
MTEPTRLPLSIEFFPPKTPEGVEKLRAVRQQLYALKPEFCSVTYGAGGSTQEGTFAAVRE
ILAEGMDAASHISCIGATRATMRENLATLKAMGVKRLVTLRGDLPSGYGMGGEFQYASDL
VAFIRAETGDDFHIEVAAYPEVHPQAKSPAADLQAFVTKVKAGADSAITQYFYNADAYFR
FVEEADALGVTVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIRAFG
LDVVSDLCEQLRAGGAPALHFYSMNQSATTLELCRRLGL
>A0A3D1WVU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerochaeta sp|TrEMBL
MKVTEIIAQAKGPLFTFELLPPLKGHTMDAINETIETLLPYNPAYINITNHQMEVVYVDR
PDGLVERRTTHKRPGTIGLAAAIQYRFGIPVVPHLICGGQTKEQLEDQLVELNFLGIENV
LALRGDPPHGERRFIAAKGGYDHTDGMVSQIAAINRGEYLDPTLRDPVATSFCIGVAGYP
EKHAEAPNFNHDITMMKRKIDAGAHYIVTQMFFMNERFFEFVDQCRAAGIEVPIIPGIKP
IQRRSDLDLLPQTFRVDLPVSLVDRIERCKTAADIRKVGVEFCTAQVAQLLEAKVPGVHF
YTQGRAEPIANVVEATYPKAILS
>A0A1F4EG81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFCSPHIGHO2_01_FULL_64_960|TrEMBL
MIAANAQGTGFPVSFEFFPPKTPEGADKLRAARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSPEADLNAYIAKVQAGADSAITQYFYNSD
AYFRFVEDTQRLGANVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>I0WTG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus imtechensis RKJ300 = JCM 13270|TrEMBL
MTRTPSIVDRIRSSSDGRVPFSVEFSPPRDEAAEARLWRAVREFERLGPAFVSMTYGAGG
STRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRGISNILVLRGDPPGD
PLGEWEKHPDGVEYAEDLVRLVRDLGDFHVGVASFPEGHYRAPDLAHDTRYLVSKLRAGA
EYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSVRRVLELSGSRLPAH
LEKRLATAAGDGPEENRAAVREIGIDVATEMSERLIAEGAPGLHFITLNFARATSEVLAR
LGDKVGSGVADPTPVTPARVS
>A0A532DM82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPQRLVDVLNRGTFAVTVEYNPPKGTNITSILENAKQLVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVRGLNNGKDMVGNKLDGSTAFTIGAAVTPEADLVGPVLAKFEVKV
KAGAQFFQTQAVYHPDVFAGFMKQVRPFKVKVLAGILLLRNAKMAEFMNANIPGMSVPNE
MIDELKAAGEKAEDVGVDIAVRTIKAVRPHCDGVHIMAIKATHRLSEIITKAELD
>A0A2K5AQ94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosocaldus cavascurensis|TrEMBL
MRMKITYEMNPPRIMASLSNSNYNDPNTPKRERFDLQSLSSDLERFYCRVRMLYGLAHMI
HVTDSVLGIPRLSSISIGREIVQKHKLRARCSIRVRDRNTNAILQLVTDAIIAGIDGLLV
IKGDEPRHSSIDSALKPSSVVKFLNEHGFSKHIRLYLSIDAENYSEDELNRKISAEPHGL
ITQSLSSLEPLVSLADRVKANNMCIVPCIMVPSPKNKASASSINLDWSRYEHDVESFVLE
AYSLCGEVMITSPNSFNDGINILKRVMYGKAYQRGTVQRGSDTVGVEYKEKEGENGGWKH
E
>A0A1I3QJ79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomicrobium apsheronum|TrEMBL
MKQHILTALGERVVVADGAMGSLLFDRGVDSSSCYDVLNLTDPALVQSIHKAYADAGAEI
IETNTFGANRVKLGRFDLAHRTREINLRGAELARGQAGPGRWVAGAMGPLGRLGIDPLSQ
EELEDIFGGQALALVEGGVDFIMLETFASLSLLLTALRGVKAVVSVPVAAQMVFTQRGRT
HSGRTARECFDALIWAGADVVGLNCGIGPKNALEVVQGLGPVPVPLSVLPNAGFPESSGD
RLIYASSPEYFARRTAACAAHGARLLGGCCGTAPEHIAALVRALDAGSSEARIVSVSPDE
VNTQTAAPTRLSRRLAEGKVILVELDPPKHLDVEPVLAAAEALSAAGVDAITIAENPLAV
PRLSNIVLAGMVRARTGVDVVVHMTGRDRNLVGMQSTIMGLAASNLHNVLAVTGDPPSAG
SAERVSGVYDLRSLELMALLAGFNEGRNHYGDSMRLPVNFCIGGAFNPNTRNMALQVGRM
EKKMTAGARYFLTQPVYSRERVDEILAATAHITAPIVLGIMPLASSRNAEFLHNEFPGIE
IPSETRERMARAGEHGQEEGVNIAWELLEYAWPHFAGVYIIPPFNRHVMALELMRRLGR
>A0A243M5N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar zhaodongensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A8XGS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis briggsae|TrEMBL
MAILRVNGIDSGDENAVVTEKPVFETSKSWSLKNYELLHERIERLIEEKTPFFSLEFFPP
RFVNGVPNFLERVERLSEGGSVFVDMTWHMGSDPANIDKVTSSSSIAASMLDYCGVDTML
HMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPGTELEDTNQFRALDMIRWIREEYG
DYFSIGCAGYPLGHPQAPSYKADLQYLKAKCDAGANFVITQLFFEPETFEKFVADCREIG
ITKPIIPGIMPIMGYESIKRIAKLSQLEIPEHXXLDAA
>A0A7W4AT92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. SR44-4|TrEMBL
MAFHHAQHAQSLNQSLSELNDINVSFEFFPPSTPAMEEILWNSIRRLEPLNPKFVSVTYG
ANSGVRDRTHSVIERIQKETNLLAAPHLTLVDASDEELVELAKHYWNSGIRDIVALRGDL
PDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDARNAQADLINLKKKIDAGANRAI
TQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVTNFKQTKRFAGMTNVAIPHWLHRQFEG
LDDDPATRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPK
>R6TQK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium rectale CAG:36|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNQYNVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>A0A3A5SWS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AM30-16|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A1E3VKV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloceanibacter stevinii|TrEMBL
MEVSFEFFPPKNPAMEETLWRAIRRLEPLRPKYVSVTYGAGGSTRERTHATVARLLSETT
LIPAAHLTCVNATKQEIDEIIREYWDLGVRNLVALRGDPPEGVGERYVPTPGGYENAAGL
VAGIKNIAPFVTSVACYPEKHPESPSVEADIDMLKAKVDAGADGAITQFFFDNEVYFRYL
DRVRAAGIDIPIIPGLIPINNFKQAASFAKRSGASVPDWLERRFEGLEDDAETRHLVAAA
VAAEQVLGLVDQGITSFHFYTLNRADLVYAICHLLGLRPAKAFAHKADESSEPTKIAKVA
S
>A0A3B6V8D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira hyodysenteriae (strain ATCC 49526 / WA1)|TrEMBL
MSDNSVENFIDKLENKDEYTFTLEISPQAKFDLGYIKDKIDDAKISDYIDAFVVTDSPFA
NLKISSILAALQLQQRLNNNKPFIATQTMRDKNSIALQNDLIGANYFDIRMVLAVTGDPI
NGGNQKQAKSVFEGNSELLIAIIKDLNKGKSLGEFAFKEPLKPIYPFCVINSYAKNNDSL
KVRLAKKANSGVKAIFTQPIYEAERLELLLEWIDELPLKNKPILVPGFFPVLTYKTAYFI
YYKLPGAYIPEDWLNKLKKASNKSPEEEKRVAVKLSSDLFHNMLKKHKKMHIMSMNNYDF
VVSLLKNI
>A0A0Q6V488|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root122|TrEMBL
MTHARGLSMRELLARGDRSFSFEFFPPKDEAGEQQLWQAITELEPYDPTFVSVTYGAGGT
TRDRTVAITARIARETGMLPVAHLTCVGHTTGEIEAILDDLDAAGVRHIMALRGDPPSGP
GTPWTPTDGGLTYASELVALIRRRPDMRIGVAAFPEGHVDAADLDQDARVLKAKYDAGAE
FAVTDMVLRASDYIALLERAEAVGADLPIIPGIMPILNLRSMERMVEFSRRQLPQEVRDR
LTPYAEDPQALRSEGIAIATELCEALLDAGAPGLHFYTLNRSKATREIFDNLRITV
>A0A1Q8Q8J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Domibacillus antri|TrEMBL
MTLLDRLKTDVLTADGAMGTLLYSYGIDFCYEELNTEKPEIIEKIHKDYIKAGADIIQTN
TYGANSIKLSRYGIENRTRELNAAAVEIAKKAAAPGGQFVLGTIGGIRGIRKSSATNDEI
IASVREQAESLLSGNPDGLLLETYYDFEELSASVQLLREMSDVPIIAQVSMHEPGVLQNG
LSLNEALHRLEGMGADIVGVNCRLGPFHTIQAFEDVTLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGRAAVLLRNEGVRLIGGCCGTTPKHIEAAKKRLAGLPPLTEKKVKTKKPIV
IQDAAPVTDISICEKAKTERTVIVELDTPKTLLTEKFIEGAKKLYDAGVDAVTMADNSLA
SPRVSNMAMGATLKMQHDVRSLVHITCRDRNLIGLQSHLMGLDALGLHDVLAITGDPTKV
GDFPGATSVYDVSSLELIQLIKQLNEGISFSGKPLKKKANFSVAAAFNPNVRVLDRAVKR
MEKKIECGADYFITQPVFTKEKIIEVHEATKHLPTPVFIGIMPLTTMRNAEFLHNEVPGI
KLSDETLERMRACGDDKEASAKEGVQIAKELLDTAAELFNGLYIITPFLRHDMSTELIHY
INELDAKKESGALHDYSSN
>A0A1S1GW71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. HMSC62A08|TrEMBL
MSQFLKHLQNNVLVADGAIGTILYSEGLDTCPEAYNLTHPDKVEHIHRSYIEAGADVIQT
NTYGANFEKLKNFGLEHRVREIHKAAVQIAKRAANEDTFILGTVGGFRGVRQEEISLSTI
QYHTELQIDTLINEGVDALLFETYYDLDELKNIVVATRRKYDIPIIAQLTASNTNYLVDG
TEINEALKQLVECGADVVGLNCHHGPHHMQRSFSHIELPEQAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPEHIRYIKSAVQGLTPVKDKKVIPITKKS
NRKPTSMMKQNLTTKVKNGPTVIVELDTPKHLDTDTFFDNVGKLDEAGIDAVTLADNSLA
TVRVSNIAAASLIKQRYDIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVASGMSYFITQPVYSKEKIKQVYEETKHLNTPFFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYIITPFQKVDYSLELAAY
SKSITANKEAIL
>G5JRI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus criceti HS-6|TrEMBL
MSKLLDKLKTDILVADGAMGTLLYADGLESCHDYYNISHPERISAIHKAYIDAGADIIQT
NTYGAKRHRLKSFGHDNDVKLINQKAVEIARQAAGESVFVLGTIGASRGLRQCDLSLADI
VEETVEQAQALLETGQLDGLLLETYYDREELEAVVKAIRPLTDLPLITNMALHEAGITED
GRPLVEALSHLVMLGADIVGLNCHLGPYHMIQSFKQVPLFAQSYLSAYPNASLLSFASDN
EKGQYRFSQNADYFEYCARLFVEEGVRLIGGCCGTTPDHIRAIKRGIKNLKPVERKTITP
LITEEELIDEISKKETLADKAKKEVTIIAEIDPPKTLAIEKFIEGIKALDKKNIAAITLA
DNSLAKTRICNLSLASLLKNEVTTPFLLHVACRDHNMIGLQSRLLGMDVLGFNQLLAITG
DPTKIGDFPGATSVYDATSFKLLSLIKQLNHGKGYSGASLKRTTHFTTAAAFNPNVHHLE
KSSRLIERKIKAGADYFITQPIFSEEIIHQLGHLTEAYDQPFFIGIMPITSYNNAVFLHN
EVPGIHLPEVFLEKLETVKDDKKACQAIALAESKKLIDCALEYFNGIYLITPFLRYDLTL
DLIDYIQKKKTLMSPK
>A0A3M5F821|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1E3LRH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas turrisvirgatae|TrEMBL
MVELAREASYEVSARDGEAIKKAGARLTPGTRISVTWMPADNDDDRVSAARQLRDAGLEP
VPHIAARMLKDEHHLDRLLGRLSAEAGVGQLLVISGDVKQAVGPFESSSDLIASSAFRKP
MLHTIWVGGYPEGHPTIDDETLRAVLDRKIATIGELGMTPGVITQFCFDAEPILQWMKAF
RERHDGVAVRVGLAGPAGIRTLLRYAAICGVGASAKALITRGASIARLLSEAAPDPVIRD
LAETPTYGELQPVGFHLFPFGGLDRTVRWMEVVAAGRFKLHSSASGFQVLE
>A0A2M9FXG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Minwuia thermotolerans|TrEMBL
MPTGLDRLDFSFEFFPPKTEAGWRGISRAAAAFKPLDPEFCSVTYGAGGSNQTGTLDAVL
AVQKASGSPGAAHLTAAGQSREAVDAAAQTFLDHGIGRIVALRGDSRDEGPYRPHAEGYA
NAAELVAGLKKIHDFDISVAAYPEKHPDSPTPEADLENLKAKLDAGADRAITQFFFDADS
FLRYRDRLAAAGVYKPVIPGILPIRDIEQVQRFAAQCEAVVPPMVVAAYEGLEQVEDRRK
RSVDLAHELCARLVRHGVRSFHFYTLNKSDLTVEICKRLAGTAESEAAVAAASAAR
>A0A1M7DZR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces paucisporeus|TrEMBL
MALGISSTRPDRAITIRELLASGHRSYSFEFAAPRTEKGERTLWNAIRRIEAVQPTFVSV
TYGAGGSSREGTVRATDRIVSDTTLTPCAHLTAVNHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPLAEWVPHPQGLAYAAELVALIKESGDFCVGVAAFTEMHPRSTDPAEDTRHFID
KCRAGADFAITQMFFDADDYLRLRDRVDAAGCSTPIIPEVMPVTNVKQIERFSQLGNAPF
PPDLAERILAVQDDPAAVRAIGIEFATQMCRRLMAEDIPGLHFITLNHSTASLEIYENLG
LHQRA
>A0A4Y6IG97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. SNU WT4|TrEMBL
MAFHHAHYAQSLNQNLAELKDDINVSFEFFPPATQEMEQLLWQSIGRLAPLKPKFVSVTY
GANSGVRDRTHSVIERIQRETDLIAAPHLTLVDASDDELRQLAQNYWQQGIKHIVALRGD
LPAGSPKPTRFANDLVSLLKSVADFDISVAAYPEVHPDASSAQADLIHLKRKIDAGANRA
ITQFFFNVESYLRFRDRCTAAGIDVEIIPGILPVTNFTQLKRFAGMTNVALPTWLHKQFD
GLEDDAHTRQLVGANVAIDMVKVLCQEGVKDFHFYTLNRAELSYAICHTLGVRPQAHALA
>A0A0Q7SLM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelomonas sp. Root1444|TrEMBL
MSTSVSFEFFPPNTPVGVEKLKTVVQELGALKPQYFSVTYGAGGSTRDKTLSAVMDIASA
GFEAAPHLSCVGSTRENIAEILATYRAQDIHRVVALRGDLPSGTATAGEFRYASELVSFI
RETQGSDWHIEVAAYPEVHPQQRYAARDLQHFADKMRAGADGAITQFFFNADAYFHFVDE
ARKLGVTQPIVPGIMPFHNYGRIAQFAQRDGIEIPRWVQMKMEGFMDDTASIRAFGLDVV
TQLCERLVAGGAPGLHFYTLNQSALTLALCGRLGLGAKS
>A0A1H2MPV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microlunatus sagamiharensis|TrEMBL
MPGPAVVAARPRLSRPGRGPTVAQLLEAGERPLVSFELFPAKDAEQHRQLWTTIRELESL
GPDFVSVTYGASGSTRDRTVSATQQIAEQTTLRPMAHLTAASQSRDELRHVVGAYASVGI
NHIMTIRGDMPGGPTVPWEAHPDGLANATELVSLVAGLGDFCIGVAAFPDLHPQTRDADL
DARLLVAKQRAGASFAITQLFFTAERYFDLVARVRALGSDLPIIPGIMPVTRISQIERFA
DLSGAALPAFVTDRLHEVEHDPALVRAAGVDLATALSEELLAGGAPGLHFITMNRSPATR
EIYARLRSSLQRK
>A0A4R1SZS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PP-WC-2G-219|TrEMBL
MSGFPSASGDLLPGHSSRGRLEQVLRRGEFAVTAELNPPDSADPEEVYARAAVFEGWVDG
INAVDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQGDVLGAAAMGVANILC
LTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDHAKFLSGRKLTAPPRVFLGAAINPFA
PPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFRAYMEKVRDLGLHEHCHILVGVGPMASA
RTARWIRSNVPGVHIPDAIIARLEGAADQKKEGKQICIDIINEVKEIKGVSGIHVMAYRQ
EEYVAEIVHESGVLKGRRPWRREQDPADAGVAERLDAARGGEMQDQESLAETAAKRPH
>A0A4R8SV69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides salmoniphilum|TrEMBL
MTTHPLDRDASVAELQDPGSIADRLAAVQPGDVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDLE
RDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEERLLRAAGGGPEENRDEVRKVGVEVTTAMASRLIAEGVPCVHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A221W9Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoalloteichus hoggarensis|TrEMBL
MIEPERACASSVPPAVHDVDGPSLEIMTAVVDRLRAQRPVFSVEFFPPRDDESERRLWRA
VRELEPLDPAFVSITYGAGGSSRDRTIRTTGRIAQETTLVPMAHLTGVNHSLDELRNVIG
WYAAVGVHNVLAVRGDPPGDPMGEWVPHPEGITYAEELVRLVRELGPFCVGVAAFPYGHP
RSADLEVDADHLVRKIRAGADFAIAQLFFQPDDFLRLRDRLAARGCDVPLLPGVMPLTTQ
RMLTKTVELSGADVPPALARRLERHADDPAAFRAEGIEVVTELCSTLLAEGVDALHFYTL
NRATATREVVGRLGLLPVRP
>A0A1M6IVG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shimia gijangensis|TrEMBL
MTAPTISLEFFPPQNLEASFRLWDTVQTLAPLEPRFVSVTYGAGGTTRDLTRDAVATLHK
SSDLNVAAHLTCVNATREETLRIANEFAAAGVNEIVALRGDPPKGSANFEAHPQGFAHSV
ELIEALAETGKFTIRVGAYPDIHPEAAHAQADIDWLKRKIDAGASEAITQFFFEAETFLR
FRDACAKAGIDAPIIPGILPIEDWKGARAFAKRCGTDIPAWLDDAFAKAERDDRTDLLAT
AICTELCSDLMDEGVANFHFYTLNRPELTRDVCHALGVTPKVTLENVA
>A0A1G3YZW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp. GWC1_61_84|TrEMBL
MSHPLIDLLAGGTVVFDGAMGTELYKRNHFVNICFDELSLRDPKVVREVHEASRKAGADV
LTTNSFGANRYKLADYLLAERTKEIAAAAARIAREVAGRELLVAGSVGPLGRHASGGALS
PHEAVDAFAEAIVALMEGGADFILFETFARSRDLGFAVEAARGLGAPYLPCMAFGDIASS
LGGESIDEFFAPCLGAGAGAAAPLMLGFNCSVGPKQMLDNLQDFVPRSTLPVLAMPNAGA
PQRINDRMFYMTSPEYFASYAKRFAELGVKAVGGCCGTGPEHIAEAARALKALDRAGAAG
VAGVAGAVSLEVVGGAAPVECAPLAQRSAFGRALAEGRWVTSVEIVPPTGWDLAKTVERA
KRCAEAGVHAINIPDGPRASARVSPMITSQRIQAEAGIEAVLHVTCRDRNLIGVQSDLLG
CAAAGINNLLIITGDPPKLGDYPYATAVFDLDSIGLVRVAQRLNVGLDIGGKPVAPPTRF
VLGVGADPTNLDQEREIERFFRKAEAGAEYAITQPVYDPEALIAYIERVRFTGVRIIAGI
WPLASYNNALFLNNEVPGVSIPESIMERMRKAGDKESARRVGIETAREILDAVRPYVAGV
QVSAPFGNVETALAVLAEE
>M5FLP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. STM 4661|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLRPKFVSVTYGAGGSTR
ERTARTVKRILNETVLTPAAHMTCVNAARHEVDAVVQEFADMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGIGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEVETA
GSAAA
>A0A6L5C5X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ephemera danica|TrEMBL
MSKEPRRLGEVLSSGQFAVTIEYNPPKGTNIAKVLENAKELVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYEMGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQVVQGLNSGRDMAGNKLDGATAFSIGAAVTPEADPVGPMLAKFEVKV
KAGAQFFQTQAIYNPDLFASFMTAVRPYKVKVLAGILLLRNHKMAEFMNANIPGVSVPQE
MIDELKAAGDKAEDVGVEIAVRTINAVQSHCDGVHIMAIKEFQQHKRQEKKLIVVTAYDA
LFTRIVEQAGINVILVGDSLGVVVQGQANTLSVTMEDMLYHTKLVARAAQQALVIGDLPF
MSYQASQEDAVRNAGRLIQAGAHAVKLEGGQAMADRVAAMTAVGIPVMGHLGMTPQSVNH
YGGYKVQGKSNDRAQALMADAKALEAAGAFGIVLEAIPASLAKDITAALSIPTIGIGAGP
HCDGQVLVLYDLLGLFDDFVPKFVKPYAHLKTDALQALRRFKEEVELGKFPSDAESYH
>A0A7K2LQZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5998|TrEMBL
MNPLSTARTAVGALLLEDFSLEMTGKDVAKLEEARETIPQGTRINITFLGNEDLRMRLEA
SRAVKRLGFVPVPHLSARRLGSRAEFAEFLAALRAEGACDNVFAVGGDPARPKGPYEDSL
ALIESGLLQEHGVRHVGISGYPEGHPDIAADVLRTALRDKSAALRARRLDGGVITQFCFD
VDPVLAWLAQLREQGITLPVRIGVPGPAGVRRLMSYAARFGVGTSASIAKKYGLSITNLM
GTAGPDRFLHALAEGHDPARHGDIKIHFYTFGGLRATSEWIARFRKEHHV
>A0A4S8IJM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Musa balbisiana|TrEMBL
MKVIDKVRGAAEGDGRTVFSFEFFPPKTEEGVENLFERMDRMVAHNPNFCDITWGAGGST
ADLTLDIANRMQNMICVETMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQD
KFVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDMIQGDGGASQEAYNNDLAYL
KRKVDAGADLIITQLFYDTDIFLKFVNDCHQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPPEITAALDPIKDNEDAVRAYGVHLGTEMCKKILSHGIKTLHLYTLNMEKSALAILMN
LGLIEESKVSRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTVGWDQYPHGRWGDSNN
PSYGALTDYQFMRPRSRDKKLQEEWATPLKSVDDINERFMKFCLGKLRSSPWSELDGLQP
ETKIINEQLSQVNLKGFLTINSQPAVNGEKSDSPAVGWGGPGGYVYQKAKAEALLKFEAI
LATSWSQFGMIQLVGSTELIRHSIILLALLGVLFACQYKAQPPIAFASTARSLDSLLQDY
VYRAFVRPRTGISYNGTVPSNLTGIKIAAIRLRSGSLRKRGVHSFKEFSIPVGVVVQPYV
RRLVLVYQSLGNWSSVYYPLPGYSYLTPVLGLLAYDAANLSATNLPELNIVVLESPISIN
FTNVTPVPSGTIARCVWFGLDGSPYFGDLVSSNVCSTYRQGHFSIVINSSEIAPSPAPSL
TPRPLPSPGGFKSSNKSKVWKIVVGAVGGFVALVFLALLVYCMQRYKQNKKVEQMEQHAN
AGVSLQTASVGDARVPVASVTRTQPVLENELVA
>A0A3D9FXL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium cutihirudinis|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCQYLGINN
VMALRGDAMKDEQSFVPKAGGNHYAVDLVRQIKDLNCGKYLHEVMDIDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A1B1A6I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tritonibacter mobilis F1926|TrEMBL
MTTPEISFEFFPPKNLEASFRLWDTVQSLAPLAPRFVSVTYGAGGTTRELTRDAVTTLHK
NSGLKVAAHLTCVSATRQETLDIADQYATAGITDIVALRGDPPKEQGRFTPTEDGFGSSV
ELIEALAAKGKFNLRVGAYPESHPEAASQQANVEWLKRKLDAGADEALTQFFFEAESFFR
FRDACAKAGIDTDRITPGILPIENWKGVRRFAEACGTTIPAWLDEAFEKAQRDDRCDLLA
TALCSELCTELLDGGVKKLHFYTLNRPELTRDVCHALGVKSKARLQNVA
>A0A3S8VLP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC 06738|TrEMBL
MATGIASTRNDRAVTVRELLASGKQSFSFEFAAPKTDKGERTLWNAVRRIEAVQPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVDHSVAELRNVIGQYADAGIRNMLAVR
GDPPGDPMGEWVAHPQGVSYAADLVRLIKESGDFCVGVAAFPERHPRSTDWDSDIRHFVD
KCRAGADYAITQMFFHVEDYLRLRDRAAAAGCATPIIPEIMPVTNARQIQRFAELSGATF
PPELADRVLAVEDDRAAVRSIGIEYATDMCERLLSEGIPGLHFITLNHSTATLEIYQNLG
LHRRS
>A0A225SUW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum aquaticum|TrEMBL
MSKHNFSIEFFPPKTAEGTEKLRATRARLAELAPKYFSVTFGAGGSTQQGTRDTVLEIIG
EGHDAAPHLSCIGSSRASLRAILEDYRAQGIKRLVALRGDLPSGYGAMDQASSEFRHANE
LVEFVRAETGDWFHIEVAAYPEMHPQARSPQDDVQNFARKVKAGANSAITQYFYNADAYF
RFVDDAAKLGATVPVIAGIMPITNYTQLMRFSDMCGTEIPRWIRLKLASYGDDTESIRAF
GQDVVTQLCQRLLAGGAPGLHFYSLNQAGPTEAIWQQLVK
>A0A5D8ZP97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium panacisoli|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVDQINNLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A4T0UZW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenobacter intestini|TrEMBL
MKHTYSFEFFPPKSEEGMAKLRTTRAQLAQFKPEFFSVTFGAGGTTREGTIAAVLDIRAD
GLAAAPHLSCIGSTRESIRAILDEYREHGIRHIVALRGDMPSGMVEAGEFRYANELVAFI
REAHGDHFHIEVAAYPEFHPQARSADEDIDNFVRKVRAGANSAITQYFFNADAYFRFVDE
AQARGVDVPVVPGIMPINNFGQLVRFSDMCGAEVPRWLRLRMQSYLDDTASIRALGLDVV
TELCDRLMSNGAPGLHFYTLNQAGLVSTICQRLGL
>A0A2H3JDK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wolfiporia cocos (strain MD-104)|TrEMBL
MKLSHKIAEYGGTRPFYTFEFFPPKTDQGFENLLSRISRLVSLEPLAINITWGAGGTTKE
RSLELAGLTQTEHGVDTILHLTCTNMEQGMVDDALRSAKERGIHNILALRGDPPRGEEYW
IPTDPRFTHGADLVSYIKSSPEFASSFCVGVAAYPDGHPDRESDDDGELEHLKAKVDAGA
EFIVTQLFYDVDGFLQWVKKVRAKGISAPIIPGIMPIQTYASFLRMTKLCGTRMPPNLMS
DLVPLRHDDQKVKDYGVALAVQMIRKLVNEGGIRGVHFCTLNLERSVTRVLEDLGWAGGS
PKVANKLISDTPVVPDSELVITPHNATDSATHTLSTAPSTDSEAGKGELNNATSWDDFPN
GRFGDFKSPAYGETDLWGSSIMSRKQALQQWGHPHTLDDLTTMFMRHLHSKIATTPFSPT
PLSPESLMIIEHLERLTRRGWWTVGSQPAINGASSEDEVVGWGPRGGYVYQKCFVEFFAE
TKDLERIERKVKGQGQGWVDFFAGNVQGECRTNVPDGGRNAVTWGVFPGQEIAQSTIIEK
ESFLSWKNEAFSIWSEWASFYPPDSTERQLLDSIRNERWLVSIVHHDYMDPSALWTFLFG
DDAVV
>A0A2M7SKR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_10_14_0_8_um_filter_43_12|TrEMBL
MKLREALAKRKFLVTTEIQAPIDEEPEGIVKTFNLVRGRVDGVSVSEVEIEGIVGDTIKT
CEVLKQNRFEAIYQTSTRQKNRLQLQKDLILAHEAGVENLLVFTEDYRITGDSLQEIMFF
HVDSGKLASVLEHIREGRTVDGKELPYKAEFILGSGVESCWGKNVPELEMKEMEEMTRIG
TGYFLTTPVFDLDRFEKFVKTVGTFGVPVIAEVMILRTAGMGRFLNRHFKSGLVPEWIIQ
KLAKASDKQKASIYLFADIVTGIKDICQGIHIITIGGEEKLRYYLDAAKLR
>A0A0D1ZHZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Exophiala sideris|TrEMBL
MADDRLPTLWSSLDPSSHYFSLEFFPPKTSSGFSNLQARLARMATALRPLFVTVTWGAGG
STATKSLELAEVCQRQLGLTTVLHLTCTNMKRSAVDEALEGAKEVGIRNILALRGDPPRE
EYRDTDESGSGGQGTDSNEDFVWAVDLVRYIRKQYGDYFSIGVAGYPEGHADESNPEAGK
QRVEYDLPYLAEKVGAGADFIMTQLSYDIQAYRAYENRLREYVDNDGKKLFEKIPIIPGL
MPIQSYQILKRITKLSHAKIPDDISKRIEAVKSDDDAVKKVGVDILSELVEQIKQSPQPE
GVPRGFHFYTLNLEKSVSFVLERSGLISSESEPSPVYSSDSDAIADDEKRPATNGHTNGD
SHESRFSKRRTSSVNAQPHNRVILDGASRSPHRSRKSGEDTDSVTPMLAQHEAGDRGTGI
PASDPTRKHNLMISEGQGALGREATWDDFPNGRWGPSHSPAFGEIDGYGPSLKVGPITAR
KLWGHPKSPDDVTDLFRRHVIGELKAVPWSDEIDVDGESSGDLGALRAETEVIRKELLAL
IQQKGYWTLASQPAVDGVKSEDETFGWGPPGEGFVFQKAFVEFFCPRQEWEEYLRPKLTS
YPPETVGWMKTDANGVVESSDDIVREETVDQPTSKRTPGTSGVNAVTWGVFRHKEIVTPT
IIERESFRAWGEEAYSIWSVWRRCFPRGSEVEQFLERMRKDLVLVNVVGQNYIGGHHGEG
GELWKILIQGAQ
>A0A0R2XUL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|OM182 bacterium BACL3 MAG-120531-bin86|TrEMBL
MSTDTSHFSIEFFPPRTPAGEEKLDIVHAELSKLGPEFFSVTYGAGGSTRDGTKRAVTRF
REAGSRVAPHLSFGGSDEGDILKLLHEYKEAGIDRLVCLRGDAPSGMGSASLYRYANELV
EFVRKETGDHFTIDVACYPEVHPQSRSVESDLEFFKAKVDAGANSAITQYFYNADAYFGF
VDDCARAGINIPIVPGIMPITNYANLARFSAACGAEIPRWLTKRLE
>A0A0Q4IHA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. Leaf26|TrEMBL
MPVIHPNWDRAPVNMVDGYSLEMTAKDVESLREAAPAIARETPVAVTFLPGEDFAARIAA
TKLVRSLGFEPMPHFSARRITSTAEFEDYLAAAVAQADVRRCFVIAGDPSEPEGPYFDSS
ALIASGAFERAGIRAIGIGGHPEGHPNMSSEQCWSVLTTKCQEIEARGMAPLIVTQFVFD
ADAVLAWLTELRARGISAPVRIGVPGPAGIKTLMRFAARCGVGASASVLAKYGISITKLI
GSAGPDKLVERFERALGEEHGKVRLHFYPFGGLEKTVAWINDYARAH
>C0VJY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. (strain ATCC 27244 / 9458)|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDADIKRFIEKVQAGANAGITQFFFNPDAYFYFI
ERLEKAGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLSAYGDDSASIKAFGHE
VILKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A4P7BQ47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas naejangsanensis|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRNAVNVSFEFFPPKTDAAEANLWSAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIEGYKAIGVDH
VVALRGDPPGSAGIGGAYTPRADGYANATELTAALGRIGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVTNFAGLQRMT
AACGAALPDWLAGHFEGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAVA
>A0A2M7GDH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium CG17_big_fil_post_rev_8_21_14_2_50_57_27|TrEMBL
MTNKFVELLSSQTLLADGAMGTMLHARGIGFDQCFDELNLTDPAAVADIHKAYIDAGAQL
ILTNTFGANRYKLNKHGLESKVAEINRAGVELARRAVAASFKDVWIAGDVGPLGMRIAPF
GRVQPDEARAAFSEQIAALAEAGADLIVIETMSDLYEIQEAIRAARDVGATFMVTQEGMQ
QNGRRRASPLPIVASMTFTRDDRTVLGDSPEKVARTLAEAGADVIGVNCSGGPAQLLRLL
KQMRQAVATSETPHSAHPYFWVKPNAGWPEQIGGRIMYPADPAYFGDYALAFCEAGADIV
GGCCGTTPRHIAAMRAALDKFPAGCKTELLETPEVLETSEVSTEIEPPSQLAQKLADGKF
VIAAEMDPPRGLSTHKLVAGASLLAEAGADVINVADSPMARMRMSAWAVCDVIQRQVGVE
TTLHFPTRGRNLLRVQGDLLAAHALGIHNVFVVMGDPTAIGDYPEAMDNYDLVPSGLIKL
IKQGFNLGMDHSGTSIGQPTDFFVGAALNLNPPEPESEIKNLHRKAKNGADFFLTQPIYR
GEEGPAFLEKYAALHGALDRPVLAGILPLVSLKHANFLHHEVPGVSIPAETRQRMEKAGE
DGPRVGVELAVELIQKIKPWAQGIYIMPQFNRYDMVAEIIEAVKE
>A0A7V6D1L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacteraceae bacterium|TrEMBL
SIGPLGARIEPLGAITYEEAKAYFREQAEALVEAGVDLLILETFSDVSEIRLAVEAAREV
AGPELVIVAQVTVDDFGRMADGSTVETFTRVLDESPADVIGLNCSVGPKVMLDTIQQMMQ
YSRKPMSAMPNAGHPVRVEGRNLYLGSPEYLSQYARRFLWAGVRIVGGCCGTTPEHIRQM
ANEVRSLRPRLKPTEVVVEEPAIKERALEKIPIEKRSSLGAKLAAGRFVAFVEILPPRGV
DASREIEGARMCARAGIDCINVPDGPRASARMSAQVMCWLIQQQAGIEAVLHFCCRDRNI
LGIQSELLGAHVLGIRNLICITGDPPRMGTYPYATGVFDVDSIGLVRIVNNLNQGLDLGG
NPMGSQTAFVIGVGANPGALNLDEEIRRFEAKVSNGAEYVVTQPVFDIGLLETFLRRIEP
FRIPVIAGIWPLTSYRNAEFMVNELRVPVPQEFMERMRRAESGEKARQEGVAIARQLVER
IKPMVQGVQLSAPFGRYDMALQVAEAIGDRSPTRSAS
>A0A7J6RPB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perkinsus olseni|TrEMBL
MARLIDKIQNRWDHDRDNGESTRVPFFSFEYFPPKTDMGVQNLYERLDRMAELGPMWIDV
TWGAGGSTSGKTFEICRNALTYHGLDVMMHLTCTDQPVKEIDEVGIRNILALRGDAPMHS
GEWEACQGGFSHAVDLVRHIRGTYGDYFCIAVAGYPEGHLEAESMEEDLAHLKEKVDAGA
DLIITQLFYDTEVFFNFVAAVRALGIQVPIFPGIMPIQSYSGFKKMTEFCKTKVPRAIAD
QLEQVKGDDQKVKDLGVEICVAMCSQIMSYGVDHFHSSGGLHFYTLNLESSVSRIIERLM
MVDSHVATRALPWRPSKASSRQEENVRPIFWSNRQKSFIQRTSCWDEFPNGRLGNQASAA
YGDFELNFRSYSKETQDKVAADRRRMWGDHVPNGDHVRRVFTAFIKGEVKRLPWCTESPT
EETLFIQKQLMRLNQCNMLTINSQPRVNGALSTDPYVGWGPGGGFVYQKAYVEFFCPESQ
LEQLIRGIEGEKYESISYMAVTADGSKVKSNTPPQGQVNAVTWGVFPNSEIIQPTVVDVT
SFMAWKDEAFALWNEWMDVYPEDDHQSRQVLSFIRDHYFLCTVVDNDFVAGDLFSKLTKI
CTPIPWETLRIENPSESDGHEVPEAHWLCTNDRPVRPRRAETSYEQYPSLSRQQDEGLRG
WRGLAGSLFLLEKGVGIQLSRVEFWTCALKLMSLITGFLETRLR
>A0A7X7R1S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MTIPEHLAAVTSGSISFELLPPVKGSSMASIFETLDQLILFNPPYINITYHREELVYQLQ
ADGKKIPAVVRKRPGTVGIAAAIQTKYKVDVVPHIICGGFSRQETEDALIDLDFLGIRNL
LAVRGDADKITGRFIAKPDGHQYAAQLLEQIVAMNKGIYQEQYVQNPEPTHFSVGVAGYP
EKHQESPNIIDDISFLKQKVDKGADYIVTQMFFDNQLFYQFVERCRKQGIMVPIIPGIKP
VAIKDHLSMLPRTFGLTIPSNLAAEINKCRDNKQVHQLGIEWASAQITDLFKSGFPLVHL
YTMGKADNIVEIAKNTIKL
>A0A6V8MJJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomonas silvestris|TrEMBL
MGALFLDRVRQEVLVGDGAIGTMLYAKGVSLEANFEHLNLVRPQLVLDLHGEYLAAGAQV
IETNTFGANFVKLDAIGLGAKVAEINRQGAKLARQAAAGKDVFVAGSLGPLGRGKAELSP
EQVRDCFRTQSLALAEGGVDLLILETFAELEELELAVLAVKETGLPVVANLAFGEGARLT
GGFSAEDAAQRLAAAGADLIGANCGAGPLELLATLKRLAQASDLPLAAYPNSGFPEYLDG
RYIYRATPDYFAGMAREMVEAGASLVGGCCGTTPEHVREVARQLAGLKPVVRKVSRRAGA
VQVGAGTASAGKGFLSHWGTRKVITVELDPPKGLDCTKVVAGSRALKEAGADAINLAENP
LARVRMGNLALAALVRREVGIEVIAHVTCRDRNLIGLQSDLMGASLLGISSILAVTGDPA
NLGEDAGASSVFDLNSFTLIKLLSDLNRGVNALGNPIGAGTGFSIGAAFNPNVQKMEVQV
GRLARKVANGAQFAQTQPIYDIARAEEMVELTAALGIPVLPGVLPLVSGRNAEFLHNEVP
GIVIPDEIRRRMAGKSGDEGVREGLAIASEFIDAIFDRVGGFYLIPPFGKHEIATELVTY
IKEKDRQPHNS
>A0A7X9DN37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MATEVMPPLGSNPSKLIRGIELVKPYVSVINFTDSASANPKMSSLACCKVAADHNAEAVL
QIAARDTTRTGLQATALGASQFGVKNILCITGDSAKVGPSPASDLGFVDIDSIQMLWILR
RMRDEGIYLDGRKIKYPPQYFLGAATSPFASEPVLQAIRDQKKVNAGAQFFQTNIVFETG
RLELWLEELDKRDVLDKVYILIGVATLKSYKVARYLHEHVPGVFLPERIMRRMEKAGDRE
SEEGVQIALEFINSIKGMKGINGIHLMTLGW
>A0A8H7T0W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thamnidium elegans|TrEMBL
MKVSDKIQKAEDEGRTFWSFEYFPPKTEMGVQNLYDRMERMQRFGPEFVDVTWGAGGSSA
ELTMDIVATSQSVYGLETMMHLTCTNMPVESIDSALKNAKACGCQNILALRGDPPQGQLN
WESCENGFSNAIDLVKYIRKNYGDYFCIAVAGHPEGHIDSQDKEDDLLRLKEKVDAGADL
IVTQLFFDVEVFIEFVKRCRNIGITCPILPGIFPIQSYGGLSRVISFNNNFVPQHIWDDL
ESIKEDDQAVKDYGIDLAIKHIKKIKEETGINGFHIYTFNLERSSRLILEKLGLVPEQEQ
VKPLPWNPSLGPNRTKETVRPIFWKNRAQSYIQRTESWDEFPNGRWGDARSPAFGEFGRW
GVTIKYPVEKRLKMWGEPKSIDDISILFAKYCKGKLEGLPWSAQKLEPETDTIKQRLAAI
NLLGYLTINSQPAVNGAKSSDPVYGWGPKGGYVYQKAYIEFFIPASKLEELTKKIGKNSE
VTYFAVNKNGDLKTNTVDDEPNAVTWGVFPGKEIVQPTIVEPTAFMAWKDEAFGLWNEWA
HTYDRQSPSAEVILDIYNNWYLVNIVHNDFQDDNGIWRLFDLEIDGDLSKKLRHNSSVF
>A0A6V7NU13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ananas comosus var. bracteatus|TrEMBL
MKVIEKIRSAEEEGRTVFSFEFFPPKTDDGVENLFERMDRMVSHNPTFCDITWGAGGSTA
DLTLSIANRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVQHIRTQYGDYFGITVAGYPEAHPDVIQGEGGATLEAYSNDLAYLK
RKVDAGADLIVTQLFYDTDIFFKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
VPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKILANGIKTLHLYTLNMEKSALAILMES
RIVRSLPWRRPTNVYRAKEDVRPIFWANRPKSYIARTLGWDQYPQGRWGDSRNPSYGALT
DHQFMRPRSRDKKLQEEWAVPLKSIDDINERFMNYCLGKFKSSPWSELDGLQPETKIIDE
HLGQINLNGFLTINSQPAVNGEKSESHTVGWGGAGGYVYQKAYVEFFCSAKKLCSLVEKC
KALPSITYIGVNKEGECVTNVGFSTVNAVTWGVFPAKEIIQPTVVDHASFMVWKDEAFEI
WTRGGPACSPRATPLGSCWSRSSEVTT
>S7U9Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. WSUCF1|TrEMBL
MLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLVYETNAEYFEETAKAFRDQGVRLIGGCC
GTTPKHIEAMAKALADRTPVTEKTVKRRTASVSVQADRPAPTPLPELARTRRSVIVELDP
PKKLGIDKFLAGAKALHDAGIDALTLADNSLATPRISNAAVATIIKEQLGIRPLVHITCR
DRNLIGLQSHLMGLHTLGITDVLAITGDPSKIGDFPGATSVYDLSSFDLIRLIRQFNEGL
SYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERMEKKIQCGAHYFLTQPIYSEEKIVEVHE
ATKHLDTPIYIGIMPLVSARNADFLHHEVPGITLSDEIRARMAACSGDPVQAAKEGIAIA
KSLIDAAFDLFNGIYLITPFLRYDMTVELVRYIHEKEAAAKERKVVHG
>A1VJI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas naphthalenivorans (strain CJ2)|TrEMBL
MNIPVSFEFFPPKTPEGADKLRLTRQALYAHLPEFCSVTFGAGGSTQEGTFSTVKAIQEE
GVAAASHFSCVGATKSTVREQLGALRAMGVKRLVALRGDLPSGYGMGGEFHYASDLVAFI
RAETGDAFHIEVAAYPEIHPQAKSADADLNAFATKVRAGANSAITQYFFNADAYFRFVDD
VRRLGVEVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGYGDDTASIKSFGLDVI
TDLCGQLCAAGVPGIHFYTMNQAAATTEIIRRLTPA
>A0A3Q8XZT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKTDEMEARLWDTVTRLEPLQPNFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDEVIQEFAGMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFD
GLQKDPQTHALVAAAVAAEQVLDLVERGVGDFHFYTMNRADLAFAICHMIGIRSHEAEAA
GSAAA
>A0A450W7U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. LFY|TrEMBL
MNLSGSNTRVFSFEFFPPKTPKGHDKLRTTWQRLSRLNPDFFSVTFGAGGSTQSGTMETV
LEIQKHAGIDAAPHLSCIGSTRVKIRKILDHYLSHGIKRIVALRGDFPPDMVKLGEFRYA
NELVEFIRAETGTDIHIEVAAYPEFHPTAPSASVDLENFKRKVDAGANSAITQYFYNKDA
YLRFVDNCERIGVHIPIVPGIMPITNYVSLAGFSQRCGAEIPRWLDWRLQEFGDDMSALQ
SFGIDVVTELCRQLLEAGAPGLHFYVLNRVQPVMTIWENLDLPKIRDSA
>A0A2S4PNN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysiphe pulchra|TrEMBL
MHISQKLAEANKSGHPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGNIA
QLTVEMVGVAQSYYGLETCMHLTCTDMGKEKVDDALRGAFKAGCTNILALRGDPPRQQEK
WTATDGGFHYAKDLVKYIRQEYGEYFDIGVAGYPEGCDDQDDPELLLDHLKEKVDAGGTF
IVTQMFYDVDNFLEWVSKVRNKGISVPIIPGIMPINTYASFIRRANHMGCKIPPTWAKAL
EDIKNDDAAVRSIGTLLVAELCRKILASGLIHHLHFYTMNLAQATRMVLDELNLTPSEGR
PLKQPLPWRQSLSPRRRDEDVRPIFWKNRNKSYIMRTQDWDEFPNGRWGDSRSPAFGELD
AYGIGLKGSSEQYRKLWGQPTSIKDIADLFVKYLQGDLNSFPWGETPITSEADSIKTELI
DLNQRGFLTINSQPAIDGVKSSDPVFGWGPPNGYVYQKAYLEVLVPNELIDEIISRVSRD
PDLTYHAVNMAGNLKTNTPSDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEAYRLGLD
WGRCYPASSLSYQLIESLMKNWYLLNIVHNDFHETLDLYRVFEGLKVSNFDQPYDATKFL
DTTTDRHNFHNEQKTNGHSLQNGLKINGNSNNNNNNM
>E8K6L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus parasanguinis ATCC 903|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFAHQPNFEVN
>A0A0P9QE28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. eriobotryae|TrEMBL
DKSAPTKYVFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTY
GAGGSTRDRTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGD
LPSGMGMASGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANA
GADSAITQYFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWI
RKQLEAYGDDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>A0A3M3WZS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. eriobotryae|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>E9AU75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania mexicana (strain MHOM/GT/2001/U1103)|TrEMBL
MSKLIGDAIAAEDANKWYTSYEFYPPRSEKAEENMMKVLVPTFMRQSPVFLDVTWGAGGR
TSDTTMRLCKDLQHAYPGTPINMHITCTNTPKGLIKEALDFSKTHGIRNILALRGDPPCG
EEFQADPDGFVCARDLVRYIHDTYGDYFCVSVAGYPEGHPSRIPQDGTISDEDNQKELEY
LKEKVDAGASFIITQLFYDASLYVKFVKRCREMGITVPIIAGLLPITTYAGFVRMVSLCK
TSIPSDVKQRVEELKENPDGLKEYGVEQCVQMIERIRASGVDYHHLHFYTLNNSAQTFKI
LKQLNALVE
>A0A1Z8LYK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium TMED15|TrEMBL
MSDFLHQIERRILVGDGGLGTQLRLRLPSNIPCLDACNIDPIFRNFVYEIHADYGRAGAD
IIQTNTYGANQLKLDLQGYGNQLESINLAGVQLASQAATEISSSQNRQVFVAGSVGPLET
NPLEDELSITEVRQAFTAQMEVLVSAGVDLLILETFTDLRQTKIATKLAVKFGLPVMVQI
SGISKGVVSDGTDVRVFAQTLSQLGASVIGLNCRGPHDLLLAAEKIARVTDIPLSVQPNA
GTPRIDQGKISTTYSVSPDHFSGFIKKFLSLGINVIGGCCGTTSEYISVIRENTDGYVPA
RRQTQIFVFPDNQKLSKSKISPNPIKQIFETNDRIVSVEMRANTFPQLRAMIKVSKNLAD
LEVDLFDVPDNAGATVNIGAIGTAFKLQQVSNIPTLIHWTTRQRNLISIQSHLLEAWALG
IKGVIALSGDHPKVGRFETAKIVTDVRGSVQLMELLKRLNQGTLIDGTSLGEPCDFYVGG
GFTITKNLKPQLKHLRRKVERGAKFIYTQPVYDLSTAEDVCQSIKNEGLDTKILLGILPI
TSLRSISFLQDNLGMYIPSIVVKQFQDIDNPKDQLLYGLSIARDLVSRLSEQNRFSVDGI
YIIPPSRMNWANKQVAITQLVQSFRKRKTEER
>A0A7L4ZR55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kordia antarctica|TrEMBL
MKVTEHITNADGKTMFSFEILPPLKGQDIKSIFDNIDPLMEYKPPFIDVTYHREEYTFKE
LGNGLLKRQVVKKRPGTVGICAAIQNRYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPEKEGHQYASELVSQIQELNNGKYLDEELQNSSQTNFCVGVAGY
PEKHMEAPSLDSDIHFLKKKIKAGAEYIVTQMFFDNEKFFAFVEKCRKEGITVPIIPGLK
PIATRKQLNMIPHRFHVDLPDDLIMGIVRCKDNKEVRQVGIEWCTQQSKELIKAGVPILH
YYSMGRSSNIEAIAKAVF
>A0A5P0ZI62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus mishanensis|TrEMBL
MADTTKKPTLSFEVFPPNSEVGVEKLTNTLNQLKDLRPEFISVTCSNHKADYEKTTIDLA
KYVHNELKLPTMVHMPAAYVNNEQVSRILDQLDELDIHQVLALRGDIIDGFVPEKDFKYA
SDLTKFIKQQKPNFEVSGACYPEVHPESANRIADIKHLKEKVDAGCDQLITQLFYDNEQF
YRFQEECAIADINVPILAGIMPIINRKQALHVLENCSAHLPKKFLAILDKYKDNPVALKD
AGIAYAIDQIVDLATNDVDGVHIYTMNSASTAKHIYDNTSAFFQFDTIK
>A0A6M7WSX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium loti R88b|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTINRILKETSLTPAAHMTCVDAARHQVDAVIKEFADMGVKRFVALRGDPAAGVGT
AYRPHADGYANGAELVGALKEAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHETEVA
GSAAA
>A0A520CGI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKITEHIKNANGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVAYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADNSFIPTKGGHCYATDLIEHIKNHNDGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNADFKFLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPDELTDALSYAKSNAEAKEIGTAAMIKQCKELIDFGAPVLHF
YTMGKPAQTKEIARAIF
>A0A243WJI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter crusticola|TrEMBL
MKVTDHLAQAQGKTLFSFEVLPPRKGENIQNLFNNIEPLMEFKPPFIDVTYHREEYMYQR
HPNGLLEKKTVRKRPGTVGICAAIKNRFDVDTVPHLICGGFTKEETENALIDLHFLGIDT
VLALRGDPIKSEGHFIPHPDGHAYACDLIGQVNDLNKGEYLNQEQDETAATNFCIGTAGY
PEKHFESPNSGADIRYLKHKVDRGADYIVTQMFFDNEQFFNFEKRCRDAGIMVPIIPGLK
PLTTKSQLTMLPRSFYLNIPEALAEAVHHASNNEAARQIGIEWCINQSKELMAHGVPSLH
YYTMSKSESIRRIAAALF
>A0A117QBB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces antibioticus|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMADWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDTDVGHFVD
KCRAGADYAITQMFFKPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPQLSNASI
PSVLKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>G7V6S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermovirga lienii (strain ATCC BAA-1197 / DSM 17291 / Cas60314)|TrEMBL
MFISEIFSSKKGPVFSFEIFPPKREYPIESIYETIEELVTLDPDFVSVTYGAAGGTKDRT
VEIAGYIKKRWGKPPLAHLTCIGAHREDILRILDELSALEVKNVLALRGDPPKDGPAEGG
DFKYAKDLVHFIREQRPGGFCVAGAAYPEGHVEAPSMACDLINLKKKVDEGVSFLITQLF
FDNELFLSFRDVARSLGIGIPITAGIMPVLNAKQISRMVSLCGASIPSALAHLIARYERD
PKGLHEAGLEYAINQIKGLVREGVDGIHLYTMNKPEVAKRIMAEL
>A0A5N8YQ50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium AD-802-F09_MRT_200m|TrEMBL
MDVKITEGAFECTGHTSIICDFSPPRSGDPRIVTQAQIGADFISVAYNPGRAVRTNSPML
AAAIQQSGKNTVFTLATRDMNKLAVQSQLLGAQTLGLQNVVVVQGDQFGPQDRARVASVN
DYQPTSLIASIVRLNQGLDFKGSQLRTPTDFCIGASVDLGRGIEEEAQLAVRKVHAGAEF
LITQPIFDVDHVARYRESYAYHAGKAGVLPIFFGLQILEKDGVLFSSVPASLQSELQGGR
SGVDIALELYQRFQEARLNNIYLMPPIKRGGTRNYDAAEEFLSKIVKV
>A0A1V4LTG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. VI4.1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAKYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1G0FXK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RBG_16_51_14|TrEMBL
MDAQKKFKAKFSFEFFPPKTPEAVSRLQETQQRLARLCPDFFSVTFGAGGSTRDRTFETV
QDIKEKTAIEAVPHISCIGHFENEIREMLELYCNNGIQHLVVLRGDLPSGSAGGYGQFRH
ANELVEFIRSVTGGHFHIDVATYPEFHPQAPAASVDLKNFKRKVDAGANSAITQYFFNPY
AYYRFIDSCEKLDIDIPIVPGIMPITNSSQLIRFSEACGAEIPRWILKRLQEFGDDRTSI
RSFGIDVATELCKDLLANDAPGLHIFTMNQAAASEAIWENLGLCDRISNGQPAHISG
>A0A5C5Q4Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas saxonica|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLDQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGEHFHIEVAAYPEMHPQAHNFEDDITNFVRKAQAGADSAITQYFFNADSYFR
FVERVQAAGVTIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQTFG
EQVISEMCERLLDGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7J9Z352|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangiales bacterium|TrEMBL
MTVAVNVHVDADRDTEDTRVRVRRMFSENVVVCDGAMGTMLHSTGVPLDRALCELNISQP
RLVRDLHAAYVAAGAEIIQTNTFNANRMRLVRVGLEDSVVEINIAGARCAREAVEDSGRP
VLVAGSVGPALSATWVPRPPGDARASTLREQIAALADWVDLVVLETFGDIESLAQAVDIA
LDECDLPIVAQLTFGDDGRTLRGEDAVAVAEALGGLDLAALGANCGVGPGALQPVVADLA
RLATLPISVQPNAGVPRRLGRQVRYVHDTEYFAEAARQFVAAGATVVGGCCGTTPAHVRA
IAKAVASLTPTRTLPPIQQPTTATVRPEIVAAEVDHPNRASWPPADQFVVIAGMQPPRGE
DIAGFVEYARELEAAGVNALAITEPAPPMARINPVGVCVVLQQSAQVDVLLPVETADHSL
AALQADLLGAHALGLRTVVCRTGSPRGVGDYPDPGPLWDVDSVRLIAALSGLNEGIDWRG
VPIPDCTEFVIGASVNTSAAELDNELDRAEEKVRAGAHFLVTDPIFDPEEAQEALSALRQ
RGVRIPVIATLAPFEDARTIERLRHELPEVAQRTTPLAVVTNDGAGPRSELDVAVEIGDK
LRTLVSGVTIHLPTPPDPRAIRLIRRLVGPGSGA
>A0A6S5KWZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFRQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A094EDR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-103|TrEMBL
MKTTWKDIQPVPTSQEFLDIVLSRTQRRLPTQIRAGFQISRIRNFYTRKVKFTQETFSEK
ISLILDGFPRLQDIHPFHKDLLNTLYDADHFRIALGQLATAKHLIETVSRDYVRLLKYAQ
SLFQCKQLKRAALGRMATICKRLKDPLLYLDQVRQHLGRLPSIDPNTRTLLICGYPNVGK
SSFLRSVTRADVDVQPYAFTTKSLFVGHFDYKYLRFQAIDTPGILDHPLEEMNTIEMQSI
TAIAHLRSAILYFMDLSEQCGYTVAAQIALFQSIKPLFANKLVFIVINKIDVMRPEDLDA
ESQAQLQALLKPGDVEMLQLSCTTEEGVQEVKNAACERLIADRVAQKLKAGTNSNGAVGG
RLGDVLARIHVARPMNGVVREAFIPDAVKEMKKYDKNDPERRKLARDIEEENGGAGVFNI
NLKDKYMLENDEWKYDKVPEVLDGKNVYDFIDPEIEAKLAALEEEEEKLEAEGYYDSEDD
LEDAEDADIRMKAELIREKRILIRNAAKMKKSLKNRAIIPRTLTKAKLTDMEDHLDSLGL
DTTSLTTRARSQSRGRSVLRSRTGTEDVMDVDSPEYEAKMRAKSRARSQSNRREDGVPEG
VIRTKAERIAKLGQRHRNRMARAGEADRHVAAAMPKHLFSGKRGAAKLQLHRRVFNCKAG
KPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHAQLTCEMVSVAQSVY
GLETCMHLTCTDMGKEKVDDALKNAYKGGCTNILALRGDPPREKEKWVATDEGFQYARDL
VKYIRKTYGNHFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATFIVTQMFYDVPNFLD
WVRKVRAKGITIPIIPGIMPISTYASFLRRCNHMNAKIPPGWIEAMEPVKNDDAAVREIG
RGLVTDMCRSILESGINHLHFYTMNLAQATRGVLEQLEMLPSEERPLKQALPWRQSLGLG
RRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDAYGIGLKGSNEQNIK
LWGEPKSVKDIANVFLRYLNADIESLPWSEAPISNEADVIKNQLVELNERGLLTINSQPA
VDGVKSSHPVYGWGPANGYVYQKAYLELLVAPELIDELLDRIARDPEVTYYAVTKSGTLR
TNAPSDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDWAHCHDSSSPSRNVI
QRVMETFYLVNIVHNDFHQRDALFSLFEGLTVPNIDKAAAPATNGDKVEEAPPAIVSNVL
PVA
>A0A228RJE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. HI2714|TrEMBL
MKTIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVM
>I7C5R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida (strain DOT-T1E)|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRICEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>I6DG03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella boydii 4444-74|TrEMBL
MSFFHASQRDALNQRLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A258N0S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriia bacterium 35-40-8|TrEMBL
MKVIDHISQAKDTLVSFEVLPPLKGKTINTLYDHLDPLMEFKPSWINVTYHRSETMFKKK
TDGTFERVEVRKRPGTVGICAAIMNHYQVDAVPHIICGGFTKRETEDALIDLDFLGIDNV
LVLRGDAAKNESAFEPEKDGNHFAIDLLSQVSNMNNGIYQDEDIKSGGKTKFCMGVAGYP
EKHFEAPNLEIDLIKLKEKVDAGADYIMTQMFFDNQKFFDFVTACKNMGINVPIIPGLKP
ITNKKQLSVLPRIFHVDIPTDLSNAINKCKTDAECEQVGTEWLIQQSKELKAFGSPVLHY
YTLGKPKVIWNVVKNVF
>I2J5T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. SK140|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKRKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQS
>A0A433MNJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax guangxiensis|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPQFCSVTYGAGGSTHQGTFGAVQEILAE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVGFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
VRKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASIKAFGLDVV
TDLCARLQEGGAPALHFYTMNQSAATLAVLERLD
>C3X5P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacter formigenes HOxBLS|TrEMBL
MPSQKSFSIELFPPKTPEAIDELRVTRTRLAELSPKYFSITFGAGGSTQQGTHDIALEIQ
QEGYEAAPHVTCIGSTRETVRERLNKYRSCGIRHIVALRGDLPSSYGVLGEFRYANELVE
FIRAETGDWFRIDVAAYPEMHPQAKSMTDDVDNFVRKVKAGADAAITQYFYNPAAYFRFM
ENVQAANVSIPVIAGIMPITNYTQLARFSDMCGAEIPRWIRLRLESYGNDLASIRAFGLD
VVTELCEQLLAGGAPGLHFYSLNRAAITSEIWKRLGLHEKKAALEPAEEKEIVSA
>A0A3S3RN83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electrothrix aarhusiensis|TrEMBL
MTLIEKLDKKFVVTTELGPVKGMLTDESLEKARSYLPLDGINVHDCPMGNLRINSVAMGT
LIQNNLNIEAVPHFTCRDRSLLGTQADLLGAHSLGIRNLLVTTGDPPKHGPYLSKAVYDY
NTFELIRLIKKMNIGLDCNGKEFGGATDFAIACTAMPTGGNLKGELERMSKKIAVGADFF
QTQVVYDAEKTLAFLAEARKLGKPILLGVMPLKSVKMARFMNEHVAGIDVPDEVIARMEN
QGATGIEITCDFIKKIIDHTDGIHIMAMGDVQGTNRIIEFVNTLVRK
>F2NEL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2)|TrEMBL
MKTDSTLEKILASGKLAVTSECGPPRGALPEKVREKANLLKGYVDAVNVTDNQTAMVRMS
SLSACILLKQLGLNPILQMVTRDRNRLAMQSDILGAYAHGIDNMLCLSGDHTSFGDHPMA
ACVHDIDSIQLINMVKNMRDEGKFQGGEKIDGPPKMFIGAAANPFADPFELRVARLAKKV
KAGVEFIQTQCIFNLDKFEKWMEGVRDRGLDEKVYILAGITPMKSVGMAKYMKNKVPGMD
VPDDVVKRMAGVPKEKQAEEGIKICVESIQRLKEVKGVKGFHIMAIEWEQKVPEIVEKAG
LLPRP
>A0A838AD65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloechinothrix aidingensis|TrEMBL
MVSGSGLAGALRAGRFVVTAELGPPRGADTDVIREKARALRGWVDAVNITDNQGGFVRLS
SLAGSLVLLDEGMDPVMQLTARDRNRIALQSDLVSAAALGVRNVLLLSGDHPSYGDHPDA
KPVFDLDSVQMVWTARNLRDRGQLLSGRSLDPPPELHIGAVENPFAPPAGFRARRLAKKV
RAGAEYVQTQLVFDISAFTRWMAEVRELGLHERAHIIAGVGPIVSPRALEHMRTKVPGVW
VPDTVATRLLRAGTEGFTEEALRLCAESIHRIRDIEGVSGIHLMAFGREHLIPEIVDRSG
LDRPRFEVNACGSRERSADAG
>A0A849PVX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MRSGSNLEKVLEAGHFAVTCELGPPKGADGEEVRELARLLKGNVDAANVTDNQTAVVRMS
SIGAARLMLDEGLEPVMQMVTRDRNRIAIQSDILGAAAMGIKNVLCLTGDHQSLGNNPQA
KSVWDIDSLQQLAMLKAMRDEGVDAVGEELKGSPEIFLGAAANPFGDPTSFRVTRLAKKI
NAGADFIQTQVIYDVARYEEWMEEARDRGLLDKVHVMGGIVPLKSAGAAKYMQKMVAGIY
VPDEVVKRMKAAEKGKKEGRKIALELIEQLRTVKGNHGVHIMAIMWEKLIPKLTEEAGLL
PRPKV
>A0A856CNE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGADVV
AALCERLMAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A3R6N580|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF36-18BH|TrEMBL
MGNTKHTKEQIRERIQQKKILFDGAFGTYYGGKYDTKQLPELANLEAPERVREIHTEYLE
AGAQILRTNTFAANSFCMDRSKEQIEETLRSGVRLAREAVAAWRERTGETKEVYIAGDIG
QIPGDALAQKDTLCREYKEICRIFLEEGADFFVFETFSEMEELLPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGEAKEIDAVGFNCGVGPSHMHRILQILEKPEGKLLTALP
NAGYPQMVTGRMLFTGDNKDYFVDRMQQMTALGVDMAGGCCGTTPEYIAELAGKLDLTQY
PQAKKDTEPEKQQAPKEDRSFYHTKEAEGRNRKLIAVELAPPMGIDDEKLMDAAHLLQKS
GVDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGI
QNFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFTQAPASYGGAINQGRRNL
EVEIGRVKKKMAAGATFFLTQPISTQESADRVRRIKEETGARILCGIMPFVSLKNATFMK
NEMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVIVMTEDFADGYYFSFPFNRVTMLE
KILN
>A0A6P4DW51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila rhopaloa|TrEMBL
MHAIEVSAGAAPRPTSYLPCVTFAPGQNASGMGEQRIGPLVAERTAQRRFFYGLEVMASG
PGGRPTCLDFNHFLPLLPTFVSVVWLGQRYWDVDPIGQVESLQLAQHLATHIPVLPHLSA
YRLEKGRLDQFLALNFSSLLAVRGDLVHEGQEFGFSQPMVEQSRSQRGAKISICVPGYPE
GYTSLGDVPQNSARNMEYLKAKVSAGADCIITQICYRPEVIVQFVKDCRAAGLTVPIVVG
LMTHESFRTYSVMEKIAGVHLPTELRQELDQLRSHHKANSKSEPNPISRYFVNLTVRIVR
HILDADLGIWGFHFFTLNHFKPVQAVLQELRDLDILIDPEQEEKQHETKMYRVL
>A0A6H9JWE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MRISDILQKKERTFSFEYFPSKTIAGISKLYETIENVKDLNPDFVSVTYGAGGTTREKSF
EIVNQIKNVIGLEVMSHFTCVGHNVEELQDSLDELQANNIDNILALRGDPPKGEESFIQT
DGGYRYASDLVKHIRMRGHFCIGVAGYPEVHPEAPNRETDLKNLKFKVDQGADFVITQLF
FNNDDYFRFVDEAARIGVHCKIIPGIMPITNFSQIKRFAKMCGAVVPQKLVERLEKVEND
PTEVALIGIEYSMKQCRDLMERGAPGLHFYTLNKSAATRILYNAVNPI
>A0A2T4MPX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus agnetis|TrEMBL
MSRLLNTLKDNILVADGAMGTILYSEGLDTCPEAYNLTHPEKVEHIHRSYIQAGADIIQT
NTYGANFEKLKAFGLEHKVRDIHEAAVAIAKRAAKEDTFILGTVGGFRGIKQGDFSLPAI
QYHTEIQVDSLVQGGVDGLLFETYYDLDELLTVIKATRKKYNIPIIAQLTASNTNYLRDG
TVINDALEQVIQAGANIVGLNCHHGPHHMKNTFSHIALPSHAYLSCYPNASLLDIENNNF
KYSNNATYFGEVAEQLIQEGVRIIGGCCGTTPEHIHHIKTSVQGLKPIKHKKVIPIHKKQ
ESTQHPSSKLNLKERVTRQPTIIVELDTPKHLDTGRFFKNIEALDRANIDAVTLADNSLA
TVRISNVAAASLIKQKYHIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNEGINTDGDALKRRTNFNIAGGFDPHVRNIDAAVRK
LETKIESGMHYFITQPVFTKEKIVEIYEATKHLNVPLFIGIMPITSYNNALFLHNEVPGI
KMTDDVLARFKAVAGDKAATYELSISICKSLIDTVHQYFNGLYLITPFERVDYSLELAAY
SKSITSTNQEVIL
>A0A833ARJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
DAVNMTENQSGRARMSSIASTRILLEEGVEPIMQMTCRDRNRIAMQSDLLGAAALGMENV
LCLTGDHQRFGDNPEAKGVFDLDSVQLIATVAQLNSGYLLSGKEMKKAPQFLIGAAANPF
AEPFEMRVIRLHKKIEAGAHFIQTQPVFDLELFTRWMEKVVEAGLHEQCAIFAGVMPVRS
VRALLYMKDNVPGMKINGGYVERMENATDPKEEGVGIAVEIISELKNITGVRGIHLLPVM
WESIVPTLVKEAELIEN
>A0A4Y8LDL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jeotgalibacillus salarius|TrEMBL
MNLLEEMKNRILIGDGAMGTLLYSYGSDQCFEELNLSQPNHIQQIHQAYIEAGADVIQTN
TYGANYHKLERYGLEEKVKEINTAAVKNAKAAAGEHTFILGTIGGIRSFRPQSIDITEIK
RTFREQLYCLLLEGVDGLLFETYYDFEELAAVIEIARKETDLPIVAHISVQDPDVMQSGK
PVAEALLELEQLGADVVGLNCRQGPFHMIKSLEQVPLPKKAYLSCYPNASLPSYSEGSLQ
YSNNADYFGEVAPAFREQGVRLLGGCCGTTPDHVRSFSQALKGLTPVTEKKVEKAEKIIL
RSHQKDLPEPLTDIVRARKSVIVELDPPKKLHTDKFIEGAKALNAAGADAVTLADNSLAS
PRISNDSLGYLIKQQGVRPLVHLTCRDRNLIGLQSHLMGLHTLGLHDILAVTGDPTKVGD
FPGAASVYDVSSFELIEMIQQLNNGMSMSGKDLGEKASFTIGAAFNPNVRSIERAVQRLE
KKITAGADYFMSQPVFSEEKLIETADSVKGLGKPVYIGLMPLTSSKNADFLHNEVPGIKL
TEQVRDRMAAVSGDREKSYQEGLAITKSLIDTALDLFNGIYLITPFMRYEMTAELTRYAN
EQAAKRGGNQRAHIIH
>A0A417BF04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM44-9AT|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A1Z9NIW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium TMED217|TrEMBL
MKVIEHINNSNNTQXXYEIIPPXRGXGIQIIXDMIEDLKKFNPPFIDVTSHSSSVEKFKN
GKTVLKRKRPGTISICGIIQNRFNIDTVAHLVCNGFTKEETEDALIELSFLGIQNILAVS
GDGNPKQNIQDGKSINRNSLELIHQVTNLSKGNYLNDIANSSTIDMCTGIGCYPEKHAFS
NNFDQEIDLLKQKISAGASYAVTQMFFDNSKYFAFVDRCRKENITIPIIPGIKILDKPXQ
IDIXPRMFKTEXPKELHNEALENIEHXEXIGTRWAIKQSEELINAGVPIIHYYLMNXTSC
MLNILNHLHX
>A0A1G4VVJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium saliperosum|TrEMBL
MKVTQHIENANGKSLFSFEILPPLKGQNIQCIFDNIEPLMEFKPPFIDVTYHREEYEFKE
LSSGLLEKKIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDMDFLGIDN
VVALRGDAVKSEIYFKPEKEGNHYASELVTQISNLNNGIYLDADLQNTNKTNFCIGVAGY
PEKHMEAPSIDSDIHFLKKKIKNGADYIITQMFFDNQKFFEFVDKCRAAGITVPIIPGLK
PISTKKQLNLIPHRFKVDLPDDLIMAVVKAKDNEAVAQIGIEWCINQSKELLKAGIPVLH
YYSMGKSENIKAIAGEVF
>A0A1V6P576|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium polonicum|TrEMBL
MVTWSTFARILSSSSNPSHCRPIHPKDAMEKKITEKIAALPPDANYFSLEFFPPKTRMGF
ANLSARLERMAQALRPLFVTVTWGAGGSTAARSLELAEVCQRQLQLTTVLHLTCTNMSRK
LVDMALDEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNKDFTFAVDLVRYIRQTHGDYF
CVGVAAYPEGHPADTFQDVQDPTRDIPYLVEKTLAGADFIMTQLTYDIEAYQKFENALRS
HASGAFKTIPIIPGLMPIHSYKILTRVTKLSHVTIPPPIARRMEELKHDDDAVKRAGVDI
VSEIVGGMRDIPSPGPRGFHFYTLNLEKTVSFILEQCDLIPSYSDAGDLAIEDGPASIPL
DFPGRALRRRRASSINSQPHNRVIVDKLSVHESSQDSVHEALADSAGVPAPPPNRSTTLL
ISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTANSARRLWGSPVDSKDM
STLFRRHVSGELHMVPWSEGGAEEDGDGLNAETELIRPELLKLIDGRGWWTLASQPAVNG
VHNDHPIFGWGPQREGFVFQKPFVEFFCSSNDYTNILKPMFAKHGHDKLTWFATNIKGDF
ESSLPIQPADVELDDLGSNPESVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDE
WRRIYPRGSPSETYLDTTKNDSWLVCVVGQQFGAGTKQGSKEEEDEVKWMWRVLAGEEA
>A0A3R6JCL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF36-18BH|TrEMBL
MKIRDILNKDTATISFEVFSPKKSTDFGNVEVAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGEIQKQHNVPTVAHLTCVCADRSSIGAALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKESGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIVPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNLSEILKA
>A0A269XYG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter fabarum|TrEMBL
MSLNRLCVELIPRSAESLEQDVKTVQTVFPAADTLNVPDLMRFPLRSWDAAAQLRPVFPR
VIPHIRAIDIAPHAPLPGAEQDGLEEILVVHGDPPADLSMRTYPNSTESIIRRYRKEAPH
LNVYAAFDPYRRAPWKELEDVARKKEAGACGFFTQPVFDYKLFDLCREWLQGENVFWGLS
PVIGPRSRSYWETTNHIVFPKDFSTTLESNIAFAQTVLRELGQDKGSAYLMPVRVKLEHY
LPALLDTVA
>A0A2V3VVD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas sp. Nm84|TrEMBL
MESQKKFSPTFSFELFPPQTPQGVEKLRLTRQQLAQYNPKFFSVTFGAGGSTRERTLETA
LEIQAEGHVVAPHLSCIGSTQQNIRVILEKYYEAGIRHIVALRGDLPSGMAQAGEFRYAS
ELVAFIRQEFGSAFHIDVAAYPEYHPQARSAQVDFENFKRKIETGANSAITQYFYNVDAY
YHFVESCESAGLNIPIVPGIMPINKFSQLVRFSDTCGAEIPRWIRKKFEGYGDDSASIQA
FGLDIVTDLCERLLQAGAPGLHFYTLNSANLTSMIWQRLNLKGNAD
>A0A7K3VEJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MALKNDARGRNIRVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTRAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGVPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFTGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRRQTKSAGAAA
>A0A6G3NNF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cyaneofuscatus|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A840WIF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubricella aquisinus|TrEMBL
MSARDTTLSFEFFPPHSPEATMRLWASVERLAPLGPQFVSVTYGAGGTTRDRTRLAIATI
RERARLNVAGHLTCVGASRAETLAVAEQYRKAGVTRIVALRGDAPKGADKFEPHPDGFSG
AAELVSALREMGDWQISVAAYPEAHPEATSMEADIEHLKRKIDAGADSAITQFFFENDVF
YRFRDKCAAAGITAPILPGILPVEHFGRMCKFAARCQADVPEWMHSAFGNCKDEEEHALL
ATAIATEQCTDLMANGVSHLHFYTLNKPDLTFNICQALGFEAQPFSMAQGAAG
>A0A426V623|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquabacterium soli|TrEMBL
MTTTTQNAWPLSLEFFPTKTPEGAEKLTAVRQQLYALKPEYCSVTYGAGGSTQDGTIQTV
RAILAEGVDAAPHFSCIGATKAGVREQLAQFKADGIRRIVALRGDLPSGYGSFGEFRYAS
ELVAFIREETGSHFHIEVAAYPEMHPQARNPEADLKAFVTKVRAGADVALTQYFFNPDAY
FRFVDDVAKARLDIPVVPGIMPIINASQLIRFSDACGAEIPRWVRSRLEGFGDDKASIQA
FGLDVVSALCERLRAGGAPGVHFYTMNQAGPVKALCERLGL
>A0A1Y0HHH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurospirillum sp. SL2-1|TrEMBL
MIDSFIEKLKYDTFLTLETTPMHEPTFEPIIEKIAAFGLDKKVDGFSTTDNPLARLKFNA
LFGALKLQTHFAKPVISTMSMRDRNKVALQSDLLGANAFDLRTILCLTGDPASASDQPSV
KGVFEGNSTLLLEIIQCFNAGIDYSGKPFKTQPKSIYPFAVCNAHANTPKNLMKKMATKI
EHGAVGIITQPVYSVENATMLLELLKDAKSAANKEQSQTQLILGFFPIVKLRTAQFLAAH
VPGIHVPPLWMEKLAKAKKISEEEEKKVGFELSRNAFLALKKVHPKIHMMSANNFELVAD
LLQS
>A0A430AXX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vagococcus acidifermentans|TrEMBL
MTILSSQKASLSFEVFPPSTKSTIASLYASLSQMEDLRPDFISVTCSNRQLSLEESTVKI
ATHIQRRHQVASLVHLTAAYLTKSQVDTVLESLQEKHISHILALRGDLYDELPRSPDFQY
AGDLIAYIKEWDPSFAISAACYPEGHPESATTLADISHLRDKVAAGADQLITQLFLDNEL
FYQFQEKCWLAGINVPLIAGIMPVVNKRQAERIIRGTRVKLPKKFLAILEKYADNPVALR
DAGLAYAIDQIVDLVTQGVSGIHLYTMNQAGIARSIYEATQSLFASTEPNRTAVIS
>A0A3N6D4K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ADI93-02|TrEMBL
MRELLATGETSFSFEFWAPKTEKGERNLWNALRRVEAVGPSFVSVTYGAGGSTRAGTVRA
TQQIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWIEHP
QGVRYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDSDIGHFVDKCRAGADYAITQMFF
HPESYLQMRDRVVAAGCDTPVIPEVMPLTSVKQLERFAQLSNASLPSSLKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A3R6P691|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM51-4|TrEMBL
MKIKDILAEGRPTLSFEVFPPKTADAYESVEKAASKIAQLKPDFMSVTYGAGGGTSDYTV
KIASTIKEEYGVTPLAHLTCVSSTREKVHHVLEELKAHKIENVLALRGDIPQDGKTPEVY
HYASELIREIKEAGDFCIGAACYPEGHPESSNKSVDMDYLKQKVDAGCDFVTTQMFFDNS
LLYSYLYRIREKGITIPVIAGIMPVTSGSQLKRIAQMSGSYMPARFLSLVDKYGDNPAAM
KQAGIAYATDQIIDLLANGIKGIHVYTMNKPDVAAQIQSNISELLK
>C4R2Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataella phaffii (strain GS115 / ATCC 20864)|TrEMBL
MKITEKLSSAHRREDAPPTFSFEFFTPKTAQGVQNLYDRMDRMYNLSPQFIDITWNAGGR
SSNLTCEMINTAQTVLGLETCMHLTCTNMTLEVIDEALKSAYDSGCQNILALRGDPPLDG
SESTGCFRYAKDLIKHIKEKYGHPDEPDVDRLIEILKEKQDAGGDFMITQMFYDVEQFIT
WCKKVRDYGITIPIIPGIMPISTYASFSRRAKWCQINVPSWFQKQLDASKDDDSEVRCLG
TQLVADMCLKLVESGYVNHLHFYTMNLEKSTIMVLEKLQLIDTHNQPVASVRDCGVESQV
TVPWRRSLNPTRVNESIRPIFWSNRKFTYISRTSNWDEFPNGRWGDSRSPAFGEVDLCDG
DLIRHSPKRAVELWGKPQSIDDVIDLFVRYLQGNLSSLPWSDGETSKEINVLLDDLLALN
RQGILTINSQPCVNGLPSNHNVHGWGPSNGFVYQKQYLEFFIPAKFLTKLISNIEELNKS
YSSNFNTLTFYAVNAQGELITNSKEDDINAVTWGIFPGKEVVQPTIVERCSFLAWKDEAF
RVFKAWSSLFKDQDQDEFEVLRDSKTRAVLDKLHDEYFLVNIVDNNYVQNPNVKIFDLFK
TLH
>A0A2M9IAW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB01373|TrEMBL
MALGTASTRTDRARTVRDMLATGKSTYSFEFWAPKTAKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEQIVSDTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMADWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFEPESYLRLRDRVAAAGCATPVIPEIMPVTSVKMLERLPQLSNAAI
PDDLKERIRAAADDPAAVRSLGIEFATEFCARLRAEGVPGLHFITLNNSTATLEIYENLG
LHHRPRT
>A0A292ABP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia fonticola|TrEMBL
MSFYHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHNIIKGIKERTGLEAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGGGKPEMYAADLVTLLKDVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGAVVG
>A0A3T1AVK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes sp. OR16|TrEMBL
MSLGLPSRLPGTPSIGALIREPAPTFSFEFFPPKTRDGERLLWQAIRELESLKPSFVSIT
YGAGGTTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRNVIGRLAGAGIRNVLAVRG
DPPGDPMGEWVRHPDGVLYAEDLVRLVREAGDFSVGVAAFPYKHPRSGDVESDTRNFVRK
CRAGADFAITQMFFEAGDYLRLRDRVAAAGCDTPIVPGLMPVTRMATIERAQQLSGAPFP
PALLRRFERVAGDEAAVRELGIETCAEMCATLLDEGVPGIHFITLNRSTATREVWQRLAP
SEVAAAA
>A0A3D1XUF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospina sp|TrEMBL
MKISEKLKSSSPVFSFEFFPPKDEAGFQSLFETIGRLKSANPAFVSVTYGAGGSTRSKTV
DLVGKINNDIAIESMAHLTCVGHQKNEIVSVLDSLQTLGIENVLALRGDPSKGEEKFVKT
EGGFSYASELVSFIKSKFSFCIGAACYPEGHIECPDLQIDMDNLKRKVDAGVDFLITQLF
FDNRHYFDFIDKARQQGINIPIVPGIMPVLNLKQSQRFTKMCGASLSDSLLAKFDGVQED
PEKVREIGINHAIDQCRDLLRSGAPGIHFYTLNRSKATLAILEHLQG
>A0A242PFC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella sp. N-G2|TrEMBL
MKTNLLFNQKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMLKILHDLKCAGIDNVLALRGDISPNVPPKDDF
RFASELVTFIKENGDFNVIGACYPEGHLEAATLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKAHDMDINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKSA
>A0A420XID6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Otariodibacter oris|TrEMBL
MSYAKEIDLLNQSIADLNGKINISFEFFPPKNEKMESLLWESVNRLKVLKPKFLSVTYGA
NSGERDRTHNIVKNIQKETGITVAPHLTGIDATPDELREIAKDYWESGVRHIVALRGDEP
AGYAKKPFYASDLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKKKIDAGASRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLVKMSKITNVKIPSWMNKLYEGL
DDDQTTRNLLGASIAIDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGARPSIKN
>A0A1B1C9Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MALKNEARGRNDIRVSFEFFPPKSEEMEGQLWHAVSQLQDWDPDFVSVTYGAGGTTKAPT
LSTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQ
PHPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQ
FFFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFD
DKPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRRQTKSAGAA
A
>A0A2A2RPK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium Tous-C10FEB|TrEMBL
MQPDRLISHLLTTQPIVRSLEFFPPKDEAGLLTLRQTATSLQRIAPDFVSVTYGAGGTTR
DRTAQASAMLKNEFGFTVMPHLTCVGHSRAELGAAADQLHQAGFRNIMTLRGDPPKGDTE
FRPAPDGLSHASELVQLLKSRHADFCLGVAGYPEKHPESLSLEIDLGHLRRKVDAGAAFI
TTQLFFDNTVYYRFVEKCRAAGITVPIVPGIMPVLSLKQVRRFTEMCGAHLPPQLIARLE
VAAENPDVVEMMGIDWALDQIRGLLANGAPGYHLYIMNRARSALALAAGLAA
>A0A259KSA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium 39-55-53|TrEMBL
MNTNNSLSIEFFPPKTPEGAEKLRAVRQALYPLKPQFCSVTYGAGGSTQAGTISTLKEIL
GEGMAAASHFSCIGATRDSVRQQLAEFKAMGVKRLVALRGDLPSGYGAGGEFHYASDLVA
FIRAETGDDFGIEVAAYPEIHPQAKSAEADLQAFATKVKAGADSAITQYFYNSDAYFRFV
EDADKLGVEIPIIPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGYGDDIASIKAFGLE
VVTDLCDQLRAGGAPGLHFYSMNQSATTLAICKNLGFTA
>A0A7U8PK25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella abortus bv. 9 str. C68|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A7Y9UJ74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. IAR9|TrEMBL
MTDLTIPARADGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETTLLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTPYASHPDGYQSSPELIAGIKKRHGDIEVSVSAYPEKHPEARDFDDDIDTLKAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARAFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A1G3ICV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax sp. RIFCSPLOWO2_12_FULL_60_11|TrEMBL
MLSLRLWSVRHARGLRRVYDLFSRLAPVVAPIARALGVTRTEALLRPLERNAKGLLFDCR
MCGQCVLSATGMACPMNCAKEMRNGPCGGVRANGHCEVKPEMRCVWVEATAGTKRIAPDH
LAHPTPLLPAIDQRKRGSASWIQVIHGKPNPAFQPPVGERITPQAQQGPLERACRLGRFV
ITVEVAPPDSANPADLLARAEKFKGLVDAINITDGAGGNCHMSSVAASAILTAHGFAPVY
QVACRDRNRIAIQGDILGASALGVQNILCLTGDDVSQGDHPQAKPVFDLDAVSLLHIARG
MCDRGEYASGRKLLTAPDLFIGSTANPFVPPFGDRIANLEKKIAAGARFIQTQFCFDVPS
LEDFMRRVRERGLHQRAHFIVGVGTLGSAKALGWMANNVPGVYVPPALLARIAAAPDQKA
EAKRVCIETIQALARIEGVAGVHVMGHKNEDTLAEIIAESGLRAQTRLQCA
>W6Q051|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium roqueforti (strain FM164)|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKVLGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAIDLVRYIRQRHGDYFCIGVAAYPEGHPADTFQDVQDPARDIPY
LVEKTLAGADFIMTQLTYDLDAYQKFEHMLRNHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIAKRMEELKHDDDAVKRAGVDIVSEIVGGMSQLPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPSYSDAGENAIEDGPASIPLDFAERASRRRRASSMNSQPRNRVIVDKL
SVHGSSQDSVHEARADSAGVPAPPPNRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTANSARRLWGHPVDNKDMSTLFRRHVSGELHMVPWSEGGAEEDGEG
LNAETELIRPELLKLIDGRGWWTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFC
SNDDYTNILKPMFAKHGRDKLTWFATNIKGDFESSLPTQPADMELDDLASNPESVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPTETYLDTTKNDAWLVCVV
GQQFGAGTKQGSKEEEDEVKWMWRVLAGEEV
>A0A7W4JPM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconacetobacter azotocaptans|TrEMBL
MPFPLTAVRPLSHAPIPGPVEVSFEFFPPKTAKMEDGLRQTVGVLASLKPRFLSVTYGAG
GSTRDRTLATVAALVRDTSVPVAGHLTCVDATRDQVDDVARAYWAAGIRHIVALRGDPTT
PGSRFVPHPDGYENAAALVAGLRRIAPFEISVAAYPETHPDAASPQADLDNLKAKIDAGA
TRAITQFFFEAETFLRFRDKAAAAGIDAEILPGILPVANIAQAYKFAAMCGAHVPNWMHR
LFDGLDDQPATRALVTTAAAAELCRQLRAGGVSHFHFYTLNRAEACQALCRLLVNPQ
>A0A0U5MDN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum sp. XM-1|TrEMBL
MSLPRSELPIAAASRKPVSVSFEFFPPKTDKMQQSLWECIERLAPLAPQFVSVTYGAGGT
TRERTHETVVRIARETALKPAAHLTCVGHAKGEVDDIARRYWDEGIRHIVALRGDMPDGQ
AYVAHPQGYAYAADLVEGLKRIADFEISVAAYPEKHPDAPSAQFDLDNLKRKVDAGANRA
ISQYFFDPAVFLAFREKAAKAGISVPILPGILPVTNFAQVQKFSAACGASIPGWMADLFQ
GLDDDPETRRLVAATMAAEQCRILAAEGVEQFHFYTLNRADLAYAISHILGVRPKAAD
>A0A2D5R9M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. CPC100|TrEMBL
MGSALQRSLEAGAVTVTAEVMPPRGGDPSHTLAMANLLRHWVQAINVTDGSRAVMRMSSL
AVCRLLLDAGLEPVLQMAGRDRNRIGIQADLLGAHALGIRNLLCLTGDSVKAGDQPSARP
VHEMESVRLLQQVSAFNRGEDPVKENLPDGPTTLFAGAAADPHCASWSGLKRRLERKREA
GARFVQTQMVMDPGVLERFCRDMAAPMELPVLAGVFLLKSARNASFINQKVPGANIPDRL
IARLDKADDPASEGIAIAAEQVRQFAGIAQGVHVMAVKAEERIPEVLERAGLSSRPS
>A0A0M2ZXM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYLAKNQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPIPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>A0A2J0Z420|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium meliloti|TrEMBL
MNGRTPYPVDCDGLRFSFEYFPPKNDEMEAQLFQTVTALSVFAPAFVTVTYGAGGSTKAR
SLTTVKRMIGEMEIRNTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGGV
YEPFPGGYENAAALVEALRARGDFEISVSAYPEKHPESPDVAADIDMVKRKVDNGATRAL
TQFFFDNDDFERYLERVRRAGIAIPIVPGILPINNLTQVQKFAGLCGARVPESIVSRLGP
LDDQPEGRFREAAHIAAEQITDLVRRGVSDFHLYTMNRPQLITAVCELIGYDPELAPAQP
ADTERPVRAVARA
>A0A1Z8SRA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium TMED44|TrEMBL
MVSSIKNALXKXEPLFSVEFFPPKNEEGGKRMLETAAAIQPHKPDFVSITYGAGGGTRET
TMHYARALQDEYNFEVMPHLTCVGHTSDELLEILEDFAKAGFRNVMALRGDPPKGEKVFQ
TVKGGLSYGSDLVALIKENFPEFGIGVGGYPEKHPESSDAFSDLSHLKTKVDAGADFITT
QLFFENQVYFDFVKACNEVEITVPILPGLLPVLSLGQVRRFCGMCEAVLPSELEQQLTHA
SEDEQPKVGSAWASAQVSELLNGGAPGYHIYALNKPLSTLQILQSVGMNAKTS
>A0A135HUP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paramesorhizobium deserti|TrEMBL
MTVHELKSPRAKTMTHIGASIELAPKQAIESQDLPGLFPAGSRVYITDIGTDTVDTLTAA
ARRVSDLGYKPVPHFACRRLTTKEALETRIRRAAEEAGVTDVLVIGGGLERPAGEFNSTM
QVLETGFFDRYGITEMGVAGHPEGSPDFSEAVAVEALRLKKNFGERTGARLRIVTQFGFD
AEHFIAWAEGLREAGIDLPVHLGVAGPAKITTLIKYAAMCGVGNSITFLKKNALALTALA
TTHSPEGVVGPIERHMLDNPTSNIKQIHVFPFGGIKKASEWLVERGTWDLNTSSPIAAAQ
>A0A7W1UVL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MAHIRDLLKSGRTVSFEFFPPKTDGAQMSLGRTIAELEPLTPSFVSVTYGAGGSTRQRTR
EVVTWVRRETAITPMAHLTCQGHTRAEISDILDEYRQAGIENILALGGDPASDGDEPRQS
DYTYATDLIDDIDAVDHFSIGVAAHPEVHPRSPDRETDRQHLAAKLRRADFAITQFFFEP
HHYVRLVEELAALDIAKPVLPGIMPITNLKQIARMASLSGAGVPGPLVERLERLSDPDDV
RAAGVEAATELCADLLAAGAPGLHFYTLNKSTATREIYGNLGLTTRS
>A0A7W4YVM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga lupini|TrEMBL
MSPLSLRPSRQASRPIKVSFEFFPPKTLEMEATLWSSIQRLAPLNPQFVSVTYGAGGSTR
ERTHATVSRLVQETQLKPAAHLTCVAATKEEVDEVVRSYWDAGVRHIVALRGDPVGGIGT
QYEAHPGGYQQTCDLVAGIKAIGDFEVSVSAYPEKHPEASSLDADIDALQAKVDCGADRA
ITQFFFDNDHYFRFLDRVRDRGISIPIVPGIVPVQNFKQTANFASKTGASVPAWLAARFD
GLDNDVETRKLVAAAVAAEQVIDLVDRGVNEFHFYTMNRADLVYAICHLLGLRDQSVKVA
A
>A0A7C3U0Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGLREKLEAGHFAVLSEMEPPKGANVLGMIQNAKRVKEAVDAFVVPEMNNAVMRMSSLGG
ALVLRNEGLPAVIQACCRDRNRLALQGDLLAAQALGIDTVIAVSGQDPSYGDHHQARSVY
DIDLLELIRVVGRLNQGRDMVGIELDGATDFFCGTTTEAGAKGKSTEVETEEILRRVEAG
ARFFITAPVFDLDLLEPYRKRLNGDTAVLIPTVMLLKSLGMVRYIRSNLPHIYIPEKIQD
RLAAAPDKVRECVLIAAEIIREVKERGYGGVYLVTLGWEHRLPDIVETL
>A0A661PZ76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MDNHYREALLNKDHFSVEWEVVPGRGSFEKAQENFISKVEQAVAYGKIDALTITDNPGGN
PSISSEIMGAEVKKLGIEPMAYFTCKDKSRNQLENLLYGLERSGVANLLVMSGDYPASGF
QGRSRPVYDLDPIHVLQLISAMNDGLEYSGMKGLIKLKTTNFFPGAVASPFKKLESEQML
QYYKLKKKIAAGAKFIITQTGYDARKFHELVQLKKQAGYDVPFIGNIYVLPFGAGRAMSR
NMVPGCVVTDKLVEILDGERKAEDKGKAARLLRSSKMYAFMKGMGYDGVHISGLGVSFDD
VVQIIEQGEELVSGWQDVMSEFDFPQKAGFYYFKRASDGLLNNESQAPRTARPEVPFSYK
FSRLVHNSCFEPRGLMFKVTQKLVDKSAESGFFRLVEHLSKVALFECMDCGDCALADVAY
ICPMSQCPKNQRNGPCGGSYEGWCEVYPNEKKCVWVQAYDRLKNYGEEGKIEDNLVPPPN
WDFFHTSSWANYFLGRDHSAKKVGIQAPAKKS
>A0A7V2TYJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKAGSRLEKLLTSGQFVVTGELGPPKGADVAVVEKKANLLKGNVDSINVTDNQTAIVRMS
SIAVSAILVRMGLEPNMQMVCRDRNRIAMQSDIFGAYALGIRNILCLSGDHQKFGNHPTA
KNVFDLDSIQMIQMVKKMRDEHRVLGGDEIEGPPQMFIGAAANPFADPFEYRVVRLAKKA
AAGVDFVQTQCIYDLDKFERFMKMVRDRGLHEKVHILAGVTPLKSVGMAKYMKEKV
>A0A7C1MR07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSHLKQILEKGEFAVTAECGPPKGADSEIVLRKGDLLRDKVDAVNVTDNQTAIVRMSSLA
ACTLLRGAGLDPVLQMVVRDRNRIALQSDILGASALGIGNLLCLSGDHQSFGNQPQTVGV
FDLDSIQLLQTVKAMRDEGTILGGDRLSARPDLFIGAAANPFADPLEFRVTRLAKKIRAG
ADFIQTQCIYNLDRFKTWISTAVDRGLPEKVYILGGVTPLKSPGMARYMKNRVSGMDIPD
EIVKRMEGVPKEKQREEGIRICVETILRLKEMPGVSGVHIMAIEWEEAVGEIVERAGLLP
RPGF
>A0A7X7QT20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTATTELHCSFAEIFARNEKVLSFEFFPPKKEARLHETFTLIESLKKCRPHYMSVTYGAG
GGTKDLTQRIVSYINNTLHVPAVAHLTCIGHSLQEIDFVLQELKREGINKILALRGDPPQ
SHPAGTPLASAFTNAEQLTRHISREKGFSIAVAGYPETHKDAPSAAADIDYLKRKVDAGA
ELIITQLFFEAEIFFKFLERVHAARISVPVIPGIMPISTISQLQRFTNMCGASIPPQLHA
ALNSFERSPADLEQFGIEYATELCQKLLSGGAPGIHLYTLNKTHQVMPIVSSLDIGRAA
>A0A661PCZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGERESVLKEKLLDPNAFCITWEQIPGRGAFELQHEEVIDNVAKAAAGGKIDAISVTDNP
GGNPALSTEMLCVQIKNAGMEPFVHLACRDKNRSEIESLLCGLAAEGVKNILVLTGDYSG
SDAFEGLAKPVFDLDPPNVLRLVEKMNEGLEHKAMRKTVKLAATDFFAGACVSPFKKLES
ESMRQYAKQKNKDSAGDKFIITQVGYDARKYHELLTWLRVNNYNIPVFVNIYVLPYGAGR
FMNSNGIPGCVVTDKHLAELAEAKKADDKGKAAMLLTSAKMYALAKGMGCAGAHIGGHGI
TYEQVEYIIDKGNELAANWESLVKEFDYPQENGFYLFEKDEKTGLNTDVYAQRPSKPSIP
FIYRFSRIAHHLLFEEKSAVYKTMKPIAAWLDTTHTPKHIFDFFEHMSKVAMFNCMNCGD
CALFDTAYVCPMSQCPKSQRNGPCGGSYDGWCEVYPNEKKCIWVQAYDRLKPYKEEGKIT
EYTVPPCDWNLWQSSSWLNFYQGRDHTAKRLGIKPPPKKESSKK
>A0A1M7LLN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerosporobacter mobilis DSM 15930|TrEMBL
MEKTLLEKLQEGTIIMDGAMGTYYAKKNGNSDGMAEWASMNNPELVVAIHKEYLEAGATI
IRTNTFAVNSVVMEIDEEEQKALIKKGYQLAKQAVTEFNQTKNFPIYIAADIGPIPVHAE
RTREEVISEYKRICNVFLEEGADIFLFETFPQVDVLKEVVSYIKEMNANACIITNFCVNK
NGYTMAGIQGNKLLKEVMNMEEIAICGFNCGIGSGHMYQFLQSVELPVNKRIAVLPNAGY
PEQLYTRMVFNNNIRYFTENMSRIKQLGVSILGGCCGTTPEYIKALQEACSNNQVSKEQV
KVRHKDILLTSNSKKEEREEGKTTKSRSIFEENLDNRIKDQRTFIERLESGKKVIAVELD
PPYDSNDEKIMSCVEALKNTSADIITIADSPMGRSRVDSLLMSLKIAAKHEVSVMPHVCC
RDKNMIAMRSTLLGAYVNGIRNLLVVTGDPVPSEQRLSTTNVFDYNSIQLMQFIKQMNEE
HFSEDPIQYGGALNPALGRVDKIIERMERKMEAGAKYFLTQPIYDEETIEKIHYIKEHVD
TKILCGIMPFVSYTNANFIKNEFSGIHVPDEIVSRYSKDMSKEEAEMIGASLGRELVKKL
EPYADGYYFMIPFNRVSMFEKMNL
>A0A7C3MYM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTGSNVERILESGGFVVTSECGPPRGADPEVIRKKGNLLKGVVDAVNVTDNQTSVVRMS
SLASCILLKEMGFDPILQMVCRDRNRIAIQSDMLGAAALGIHNVLCLSGDHQKFGDHPKA
KNVFDMDSIQMIQTVKTMRDEGTFVGGEEVKGRPMLFIGAAENPFADPFEIRAARLHKKV
KAGVEFIQTQCIYNLERFERWMTMVRDRGLHEKVAILAGVTPLKSVGMARYMKNQVPGMD
VPDEVIERMKAVPKEKQAETGIQICVETIQRLKEIPGVRGVHIMAIEWEEKVAEIVKAAG
LLPRP
>A0A6N7FGG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MAHIRDLIAGGPTLSFEFFPPKTDEGQRSLEKAIGELDLLEPSFVSVTYGAGGSTRERTR
DIVVGITATHDYPAMAHLTCIGHTRAEIEELLADYAANGVHNILALAGDPPVDGSPATGD
FRYASELVQLIRSVGDFSVGVAAFPEVHPRSETNREDRAHLAAKMAQADFAITQFFFDPV
PFLRLRDDLDRLGCATPLLPGIIPVLNPASVRRFADLNGARVPPRFWSRLEAATPDERVE
LAVEHAVELVSELVAEGVPGVHLYTLNRADASARIAGAFRLGA
>A0A843KP03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccales archaeon|TrEMBL
MSVSRLQEVLDSGKFAVTAEIGPPRSAETGRLREMARMLRGSAHAFNLTDNQAANVRMSS
IASSVICLQEGLEPVMQMTCRDRNRIAMQSDVIGASALGIRNVLCISGDHQTFGNHPQAK
NVYDLDSIQELMVLRNLTKGTNWSGEALPEPPQLYLGAASNPFADPFEFRVTRLGKKVDA
GAQFVQTQCVLDVERFKRFMSLAVERGLHEKVHIIAGVIPLRSHKAALFMKNKVAGMSVP
DELVDRLRKASDPREEGIKLCVETMNELSSIEGVHGVHITAIAWEDIIPRLVNESGLRP
>A0A661JI04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRFEELLDSEQFLIIAQLEPPKGTDTSQLLRCADTLKGRVQAVMVPEMSGAIMRMGSIGT
SFLLKQRGLETIVNINCRDRNRLALQADLLSAYTLGLENLFVSEGDEITSGDHIEAKPVK
DLNVIGLLEAIKKLQKGTDLSGNDLFGIPKFCVGSEVNAGLQRGALELEVREMEKKIKAG
ANFFFTPTIYDLKVLENFMKKVSPFKVPVFPQVTILKSVGMARFMSRHLEGVNIPEEVIN
RLGKAPDKIKEGIIIAAEMIKNLKDLCRGALLVAIGGGERMPQVLDHVGI
>A0A661MP56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSETKTPSKLEKILSSGHLAVTSECGPPRGSDPEVIRKKAQMIKDYVDAINITDNQTSVT
RLCSLASCIHLKLMGLEPVLQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQKFGDN
PQGQNVFDIDSMQLIQLVRLMRDQGKFLGGDDITRPPKMFVGAAANPFADPFEIRVPRLA
KKVAAGAEFIQTQCIYNVERFKEWMKGVVDRGLHEKVYILAGVTPFKSAGMAKYMKNRVP
GMDVPDELVKRMSGVPKEKQPEEGLKICVETIQQLKEVEGVSGFHIMAIEWEEKVPEIVE
ASGLYPRPKVDG
>A0A512PQI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus rapi|TrEMBL
MSLTELFNQKTVFSLEVFPPKKTADKDAILPTLEQLQSINPDFISVTLGAGGTDHCDRTV
EVANLIQNQLKIPAMAHVPGLYQTKQQVLDLLDQLSSINVANILALRGDHIPDKQPAGDF
NHANELVAFIKENRPNFSIASACYPNCHMEATDFVDDIGNLKRKVDSGVDHLITQLFFNN
QAFYDFKEKTEIAGINVPIEAGIMPCTNRNQIARITQLSGVPLPKKFRAIMDRYQDNKEA
MRDAGIAYAVDQIIDLVSQGVAGIHLYTMNHPGIAKQIWQETRAVINAK
>A0A2N2H0A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-21|TrEMBL
MKLKEALEKKKFTVTSEIQTPFDEDPASLMKALESVRERVDGFSVVETEINGVVGDSIKI
CKELQNNRFEAVYRTTIRDKSRPKLLKDLALAHKSGVENILTFTEFYRISGDSLQEMMFF
HVDSGKLQSVLEHLSEGRNVDGHELPSKASFLVGAGVDCRWGSDVPSMELKEMESMRELG
TGFFLTTPVFEIDRFEKFMRQAKQIGVPVIAEVMILKTAGMGSFMNRHVNPNMVPEHVIR
KLAKSTDRQKSSIEIFAETVRGLKEICQGVHIITIGAESKLKLYLDAAKLY
>A0A5J5LWH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa EAWAG127a|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNTSHMLEMALWLKNRVHAVNITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A2N3IBH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raineya orbicola|TrEMBL
MTKVTQYIRESKETLFSFEILPPLKGESIQQLFKAIEPLMEFKPKFIDVTYHREEYVYKK
RENGLLERQRIRKRPGTVGICAAIMNHFKVDAVPHIICGGFSKEETENALIDLHFLGIDN
VLVLRGDAIKSEGTFIPEPDGHAYASELLQQVVNMNKGKYLDEGLQASATDFCIGVAGYP
EKHFEAPNLQTDLKYLKLKQDLGADYIVTQMFFDNQKYFDFVSKCREMGITIPIIPGLKP
ITTQKQLTILPAIFHIDIPDELVKAVESCKTPEQVKQVGIEWAIQQSKELIQFGVPVLHY
YSMSKSDAVRQIAEAVF
>A0A3S9SMH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eikenella corrodens|TrEMBL
MQHNTLSFEFFPTRTPEGREKQKITRKQLSQYQPEFFSCTSGAGGTTREGTMQTIRDILA
EGMAAAPHIPCVGLDAGELTELLQEYKDLGIRHVLALRGDIPSGMGLGATGLHHANELVE
LIRHRFGDWFHIEVAAYPEYHPQSRSAEDDIQSFVRKVKAGADSAITQFFFNADAYFRFL
DDVRGRGVEIPIVPGIMPIANFSKLARFADMCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCGRLLRHGAPGLHFYTLNQAGLSSTICQRLGY
>A0A661M5V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRIADLYAADGSSVLSLEFFTPKNEAGRRALFRAVERLGAIEPGFVSITCGAAGTTRERT
ADLAIELQERFGLTAMAHLVCTGTTQSELAETVRHMQAHGIDNILALRGDPPKGATDWTP
VEGGFRHADELVAFVRERFSLGIAGACYPEKHHEAPTLEADIRNLKRKVDAGAQFLITQL
FFDNDQYWSFLDEVRAEGIDVPIVPGIMPVLSLANLQRIASLSPGTTIPPELEAAFRKAG
DDDEASLQAGVSFAAQQCRALLANGAPGIHFYTLNRSKATLQTVAQL
>A0A2E5YRD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLISEIYRNSKDPIISFEFFPPKTDAGYRTLFRTIEDLKQLAPGFVSVTMGAGGSTRSKT
VDLTVEITREIGLVTMCHLPCTGFRPREIGGILEQLKAGDVHNVLALRGDPPQDDPDFEA
PTDGFRYANELVAYIAERDDRDAFSIGAACAPETHPEAPDAATDIANIKRKVDAGADFLV
SNFFFENAHFFDFVERCRAAGIEVPIVPGIMPIATVSGIRRMAAMNGTAIPAELDAELER
VDDDAKATYALGVRWATIQCEELLARGVDGIQFYTLNRSPASREIFENLFG
>A0A534WZ21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKVSQLYADGRPVVSFEFFPPATAAGEEALVRTIDALRPLGPGFITVTRTGTKPREAPVE
LVTRIRALGLEGAAHVTCIEASREEIAAHCDLIERRGIENVVAIRGDQPKDPGFRPPANG
FRYALDMIRFIRERGHHFCLIGGGHPEGHPECRDRERNVEHLKMKVDAGLDVVITQLFYD
NRDYFAFVERARRAGVGVPLVPGIMPITNWPQIERITTLSGNQVPPRLRDALERARDDEP
AAMAVGIEWATRQCAELLRQGAPGLHFYTLNRSPATRAIFENLRREGAIPR
>A0A2E7ZHA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKIADLYQKKTFVFSIEIFPPKNXESLERLKLRLEEFKSYHPDFISVTYGAGGSTRENTH
ELASFIQNDLGIETMAHLTCVSHTRQEIEEVLEQFHQSGIENLMALRGDPPSGXKCFQRP
SGGFAYAVELIQAVRSLNGFCIGAAGYPEGHVENPDKEADLRHQLAKVEAGADLLVSQFF
LENEHFLKWRDRLRREGVEIPIIPGLLLPSSPDALFRMEELCGVLIPLSLRQKLERYAGD
PNALKEIGWLHLAEQTEALIGEGIEGVHLYALNCLETIRRFSELIQPSFSFQQTYPENPT
RRSFTEKTEMHVTA
>A0A661TBV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MPLQEKIRAGKFVVLGAFEPPKGADFSSLHESAMLAKGRLDAIVIPEMANAVLKASSLGA
CAFLQKTGVETVYQVCCRDRNRLALQADILSAGALGIPNIMAVGGEEIQYGDHPQARTVN
DLNLMELLETINRLQKGKDLAGIEIRGAPRFCIGSDIDTGVSGGLLDIELENLEKKIENG
VEYVITNPIFDVRRFQQFLKRVDTSRIKVIPTVLLLKSAGMARYIDRNVKGMTVPAEMIR
QIQKAPEKISACIRIAAELITRLKEIGMDGVLVSTMGWEDKLPQVLDEAKL
>A0A3C0J8Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp|TrEMBL
MKIIDLLKSDKVTVSFEVFPPKSEANYESIYNAAMNVAALKPAYMSVTYGAGGSTSKSTL
DIAGDIQKRYDVCTIAHLTCAGADKDDIHKSLDGMRTKGIENILALRGDRPKDYDGDPFA
HYRYASELISEIKEYAGDGFCIGGACYPEGHVDAANKKEDIGNLKKKIEAGCEFLTTQMF
FDNNIYYNFLYRIREQGIVVPVVPGIMPITRATQVANALKLSGSNMPERFRNLVDHFGTN
PAAMQQAGIAYATDQIIDLIANGINHIHVYSMNKPEVAAGIQKNLSEIIK
>A0A534YUU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKITDMLRFAAERGEPVFSFEFFPPKNDAGVSGLFETLRALRPLAPSFVSVTWGAGGSSR
GRTLEMVTRIKRETEIEAMAHLTCVGASRKELEEQLAVICDAGITNVLALRGDPPRGQRE
FIVHPEGLAHSNDLVKLAREVANARGVDLCIGGACYPEGHPEMRDLSQDLRHCKLKVEAG
ADFLITQLFFDNRRYFEFVGRARAAGIDVPILPGLMPVTNVDQIERFTALCGAHIPAGLS
AALRARRDDPDAALQLGVAYAALQSADLLRSGAPGVHFYTLNRSTATRAILAALRAQEPW
REG
>A0A661SG92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLKEALGKKRFVVTSEVQAPMGDDNPEELVENLKRVRGRVDGVSVTEVELEGIVGDTIK
TCEILKDNRFDAIYQTTTRDKNRIQLQKDLSLAHDAGVENLLVFTEDYRITGDSLQETMF
FHVDSGKLASVLDHMREGQSVDGKELSGKMDFTMGTGVESSWGKNVPRQGMNEMETMREI
GAGYFLTTPIFDLDQFEKFMRQVGTFDVPVIAEVMILRTAGMARFLNRHFKSGLVPDWII
RKLDKAPDKQKASIELFTDTVNGLKDICQGVHIITIGGEEKLRQYLDAAKLR
>A0A6A8AB86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endobacterium cereale|TrEMBL
MQTKAPEQKGRHAFRLSFEFFPPKSLEMEAHLWESVSDFTEWDPEFVSVTYGAGGSTKAP
TFSTIQRLMSDTPMATASHLTCVDAAREETLAVIEELRAAGVRHIVALRGDPSAGIGTAY
QPHPEGYANAADLVAALKDVGGFEISVSAYPEKHPESTDTNADIEMLKRKADNGADRALT
QFFFDNDVFERYMDKVRAAGITLPVVPGIMPIQNLSMLKRFAGRCGSTVPEFLDRRFAGT
EDDAVARAEVAADVAAEQIQDLIRRGLGEFHIYTMNRSALTNAVLERLGRQRVSVKEGAV
A
>A0A3R9QMY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salibacterium salarium|TrEMBL
MNIISEVKRRILIGDGAMGTYLYEKGYNGSFEAMNVREPKVIEKIHQEYVEAGADVIQSN
TYAANRVKLEKYQLEDEVAKINQEGVKLAKKAATNDTFVVGTIGGIKGVQQNDKTKEQIQ
AAFKEQADALLSENPDGLLLETFYDLSELLDAIKIVRELTTMPVIAQAALGEVGVMHGGI
SVKEAFEQLKEAGADIVGLNCRMGPYHILRSLEPVPLMDDVYFSAYPNASLPDLDDGRFV
YQSNPNYFYERALDFKKQGVRLIGGCCGTTPEHISEVAKAVKNSAPIETKEVEYITQVET
PTSSSDSSFSYQLDDVSDENPSVIVELDPPKKLSTEKFVEGAQALYNAGADAVTMADNSL
ATPRIDNLAMGAIIKDQTNARPLLHIACRDKNLIGLQSHLLGLHALGIQDVLAVTGDPTK
VGDFPGATSVYDMNSLKLMSLMKEMNEGRSFSGKSLGEKTSFTVAAAFNPNVRNLHKAVQ
RLEKKIEAGADYFMTQPIYGENQFEEIYEATKHLSTPIYVGIMPLISSRNAEFLHNEVPG
ITLTDDIRERMAQCGEDKDKAREEGISISKDLIDKALQYFNGLYFITPFLRYDITAELTS
YVRQKNL
>A0A396LLD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. AF25-18LB|TrEMBL
MNIKEYIKEQRLITDGAMGTYYEEKYSEDTVIAEKENLKNPEQIKEIHLEYLRAGARLIR
TNTFAANTMFLADMQEVKETVRAGYEIAKEAVASFQAENGKEIPVFIGADLGPIYDLDHQ
DYDNVLQEYKEICDTFLSCGADCFVFETQSDFTYIEPVTAYIKEKSDAFILVQFAFDKSG
YTRSGLSMQRVAVEASEMENVDAYGFNCELDSTHMYQFMKNLKFSSDKFVSALPNAGYPY
TLRGKTIYSNNASYYAEKMKDIAALGTDILGGCCGTTPEYIALLSGELQDVPKAAKKIEN
VVTQEVTRTPSIFEEKLSRGEKAYIVELDPPFSEDASKVMKGAEDLRKCNVDLITLSDSP
MARARMDAGQLAVKIQQKTGVAVMPHISCRDRNVIALRAGLLGMHMNDVRHFLIVTGDPV
SRADRERVTSVFDFNSIKLMQYVKEMNLEVFAQEPVYYGGALNYHGANPDAIIERMKRKA
EAGCGYFLTQPVYTEEDVERLTYIKEHIDTKIMCGIMPLVSYKNAMFVKNEMPGIHVSDE
IVNRYREDMTREEAEEVAIELSVEIAAKLYDIADGFYFMTPFNRTGLIARIIEAIRQEEE
RR
>A0A644W1S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MKITEHIANRRGKTLFSFELLPPLKGENFEGISQAIDPLVEFDPVAVDVTYHREEIVYKE
RPDGLIEKRTIRKRPGTVGISAAIKFKYNIDVVPHLICGGFTREETENALIDLYFLGIDN
VLLVRGDNPAGEKVFRAEPGGNFYALQLVKQAVNMNRGIYLEEEIINANPTNFCIGVAGY
PEKHAESPNMAADIVHLKEKVDAGADYIVTQMFFDNADFFRFEKACREAGITVPIIPGIK
PLSLKSQLSALPRTFSIDLPEALVREAEKCVSNQQVRQLGVEWAISQSRELIRHGVPVLH
FYSMGKSDNIRAIAREVF
>A0A6C1S175|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinilabiliales bacterium|TrEMBL
MKVTRHYEGNGTRLSFELLPPLRGSSIESVYGTIDRLVEFNPACINITYHREEKVTITKP
GGTRGTRVVKKRPGTVGIAAAIQHKYGIDVVPHIICGGFTRQDTEDALIDLDFLGIHNLL
VIRGDGNRETGVFEPEEGGHAHAVDLVCQIMDMNRGIYLDNYINDPAPTAFSVGVAGYPE
KHYEAPDMKTDLEYLKMKVDAGAEYIVTQMFFDNRVYFEFVRRCRESGISVPVIPGLKPV
AIKRHLDILPDVFGVTIPQELAGQIRACKSDKDVYSLGIEWASMQSAQLKGAGVPAIHYY
TMSRPDNIVEIVKRVF
>A0A160ILG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fictibacillus phosphorivorans|TrEMBL
MSLITDLEQNKILIGDGAMGTLLYSYGSDFCYEELNLSQEEQIYNIHRAYLDAGADIIQT
NTYAANYSKLERYGLQDHVKEINKAAVHIARKAAHNEYVVGTIGGIRGIKPNSISLDEIK
RSFREQLYCLLMENVDGIQLETYYDLEELETVLEIARKETSLPIIAQVSLQEVGFMQDRT
PISDALIRLENIGADVVGLNCRLGPYHMLMTLDEVPIPKRAYLSAFPNASLPSYADGRFK
YEGDADYFKECAHLFRQQGVRLLGGCCGTTPAHIHAFSSELKNLKAITEKIVKQRKQKIV
IQTASKPKYVPLSEEVKKKQSIIVELDPPRKLDTSRFMEGAKALKEAGIDALTLADNSLA
SPRVCNSALGSIVQSQLNLRPLVHITCRDRNLIGLQSHLMGLHTHGIHEVLAVTGDPASV
GDFPGASSVYDVTSFELIKLIKQFNEGLSLSGKELGEKTSFTVGAAFNPNIRSIDKAVER
LEKKIAYGADYFISQPVFSEQRLIETYEATRHIDKPIYIGIMPLTSSRNAEFLHHEVPGI
KLSDSVRDRMGKCKDDPTQACKEGLLIAKSLLDTAMELFNGIYLITPFMRYELTVELAQY
ARANSPSLLARRSQNA
>A0A6L7JSC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MGTVLYESGVFVNQCYDELNLTEPDRVLGVHADYVRAGAQLIETNTFGANPVKLEPFGLE
PSLHEINVAAARLARQAAGERAAVLGAMGPLGIRIEPWGPTSVDEAADLFGRQVAGLAEG
GVDGFMLETFSDLDELLQAVRAVREVAGEAPIFAQMTFGDAGHTEYGATIEAAAAALEDA
GADVIGLNCSVGPSSMLFGVERMAAATSRPVSALPNAGLPRDIGDRKIYLASPEYMARYA
RRMAAAGARFVGGCCGTSPEHTRLTATLLGTHGPGPARVAVSSPGEADGHAATEPPPLAG
RSALGRRLARGEFVGAVELTPPHGWDPGELLAAAGRLRDVGVHAVHIVDGPAHRSRIAAL
PAAIVIERELGMETVPHYSCRDRNMLGMLSDLLGAAAAGLRNVFLITGDPPRGGPYDTGG
VYDIDSIGLTNVVRQLNLGLDPGGSSIGAPTSFVKGVAANPGAVDPEEEIRRFAWKAEAG
ADFAVTQPIFDPEKFLAFACRIEEFGVPLLVGLWPPLSLENAEFLAHEVPGVDVPLEVVE
RMAAAQAQGAEAAAREGVAMAREVLNAVRSHAAGVLVSTPGNEVDRAAAVLRDP
>A0A6B8J5X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAPASQPEEAFINTFSLEVSAKAMPALRAEVGRIAHGTTISIPYMASEDDDVRLAAARM
VRELGFEPMPHLSARRIGSRAALERFLERAASEAGVEKCLLIAGDLSAPAGPYADSTSII
ETGLLERCGIKVVAIGGHPEGHPAMTAEDRWHVLEHKCLAIEARGMAPLIITQFAFDADI
VLTWLDALRARGITVPVLVGVPGPASIARLARYAAMCGVGASASMLARYGISISRLLGTA
GPEVFVDRLLSGLTAGHGQISPHFFPFGGIAPSLDWIERYRRRTSAASV
>A0A0F5ZQQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RTEHGDAFHIEVGAYPETHPQATDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWIGRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLNCCGAEARHADRIGATLRG
>A0A2J0SSP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAPGSLRTEAFINTFSLEVSAKAMPALRAEAARIPHGTTISIPYLASEDDDARLAAARM
VRALGFEPMLHLSARRIGSRAALERFLERAASEAGVEQCLVIAGDLATPAGPFADSASII
ETGLLERFGVRVVGIGGHPEGHPVMSSDDRWQALERKCRAIESRGMAPLIITQFAFDADI
VLAWLNVLRARGINVPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGVSIGRLLGTA
GPEVFVDRLVQGLTDAHGMISPHLFPFGGIAPSLDWIERYRRRGPFPRVRR
>A0A644W0V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MQVIDILNQAKRPLFTFELVPPLKGGDVQTLLETVRQLSRFEPAYINVTNHQQEVVYIER
PDGLLERRTVRKRPGTIALSALIQYTFNIPVVAHLICGGMDQDELEDALVELNFLGIENV
LALRGDPPNGEKRFVPVKGGYEHSCELVSQIRDLNRGKYLDQDLQNAQKTHFCTGVAGYP
EKHAEAPNLERDIEMLKYKVDCGADYIVTQMFFDNAVYYRFVDACRKAGITVPIIPGLKP
IGSKRDLATIPQTFHVDFPSELVELLSKATKLSEIREIGVHWCTLQTKDLLAHGVPGVHF
YTLGKAESVASVVRSCY
>A0A4P8PR78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. SGAir0479|TrEMBL
MTFDAVRGRSSAGWVTQTPSIVDRIRSSDTSQGGRIPFSVEFSPPRDEAAEERLWRAVRA
FERLGPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVGHSIDELRAMCGAYA
DRGISNVLVLRGDPPGDPLGEWVKHPEGVEYAEELVRLVRDMGDFHVGVASFPEGHYRAP
DLDHDTKYLVQKLRAGAEYSITQMFFDVEDYLRLRDRVVAYDPEQGEKPIIPEIMPITSL
RSARRSLELSGSRLPEELETRLRRAAGDGPEENRAAVREIGIEVATEMAERLISEGAPCL
HFITLNFARATSEVLTNLGMSASAAV
>A0A0X3V4T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces regalis|TrEMBL
MALGTASIRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGEWVRHPQGLTYAAELVELIKTSGDFCVGVAAFPAMHPRSADWETDVRHFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAAGCDTPIIPEIMPIASMRTLERIPSLTNAAF
PDALKERILTAKDDPAAVRSIAIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHPPQA
>A0A1H0G7N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium sp. OV277|TrEMBL
MSFFRQSRRADLGTNIKVSFEFFPPKTEVMEERLWETVTRLAPLNPEFVSVTYGAGGSTR
ERTARTIKRILTETDVNAAAHLTCVDATKEEVDTVVREFAAMGVKRFVALRGDPAGGVGA
HYKPTPGGYENGADLVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVEKVRRAGIYIPILPGILPIHNFTQVTNFCSKAGTHIPAWLAERFE
GLDNDPQTHALVSSAVAAEQVLDLVERGAQDFHFYTMNRADLAFAICHLIGIRPASGTLE
PALAGAA
>A0A552E509|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa Ma_SC_T_19800800_S464|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFDRLDKFMEQVATIADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDAAGILPIHN
>A0A173MFS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Filimonas lacunae|TrEMBL
MTIFLYFHAFIEQKTSFKQQYSMKSILRSKIAEGKSGLVFYSLTPPKITTEAERIEAISG
NQIQRLKNLDVDGLILYDIQDESLRTEKERTFSFIPTLAPEHYSKQYLAQLDIPKIIYKS
IANQSREQFAGWLQQNQDIECAVFVGASSHQQVAATNFSLTDAYQLKKESGYPFMLGGVT
IPERHSKKGDEHLRMFSKMNNGCSFFVSQCVYNLNDTKNLLSDYYYSAAEAGNSLAPIIF
TLAPCGSLKTLQFMEWLGIEVPKWLYNDLKHSKDILESSISTATKIAAEILNYAQAKNIP
VGFNIESISIKKEEINAAQELLNNVLSLLRPKKQPASTDAAVIAAQSPLTASFQ
>A0A1B7W1A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanizomenon flos-aquae LD13|TrEMBL
MPDTQSYSAFNNFRKASLTGEFLITAEVAPPKGGDMTHTIKMAATLKGRVHAVNITDGSR
AVMRMSSLVASAILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDNPQAKAVFDLEAVRLLQLIRNMNQGIDFNEKPLTDGKLDLFAGAAVDPQSRSWSGLQS
RFEKKIAAGAQFFQSQLITDFEILEKFMDKIACGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEEGMKIAAEQVQMARGLCQGVHIMAVKREDLIAPILDLAGV
EKVS
>A0A081R2K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1H5WDR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. ok061|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDVAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7L3PNX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xiphorhynchus elegans|TrEMBL
MVNEAQQSCSGSSSSRSDGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDRW
FSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCSNQTKEDITGHLQKAKRLGLKNIMALRGDPAGEEWQEEADGFNHAVDLV
KHIRSEFDDYFDICVAGYPKGHPEAESYETDLRHLKEKVFAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVVEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVMEDTFELLN
>A0A1N6GZ71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. GAS332|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLASLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFAHKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTDLCRRLIDAKVPGLHFYTLNGAAATKAICERLGA
>A0A7Z0D1A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spelaeicoccus albus|TrEMBL
MPTPSTNRLALSYELFPPRSMAAGNLWTTIRELESTAPDYVSVTYGANGGNHDTALTLLS
ELVGRTTLRPLAHLTCVGGTRNSLRRTVTDLLDLGVRGVLALRGDIPDGYVPPDGAVDHA
VDLIELIRDVERGNAAQLAAGRIAVGAAAYPTRHPESATWQQDIEVLAAKQAAGADFAIT
QVFFDASRYAALVRRARDAGVTIPIIPGILPMTSLRRVRTLARLAGIDPPARLCRRLAHA
GSEADARRIGVDATVGLLRAALDVGAPGLHLYTFNQHSSALAVLDALNLPARNGAPTESE
IA
>A0A855H446|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas arctica|TrEMBL
MALSLKEKIVDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQDRPFAFKQTVDPREYSHLLRNLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDL
QNVVLVGSPSSIGDIKLSLPDAYKAMAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGITPQRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKLIA
>A0A8J5D0F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chionoecetes opilio|TrEMBL
MTLLAYMRKTNQIVMGDQPYMFEPEYEVDEQVLAEPAEVDAGADFVITQLFFKAQTFIRF
VTDCRAIGIECPILPGIMPIQSYESLRHIVRLSKLDVPQDIIDIVTPLKDNDEAIRNYGI
HQTYTLIKELFEADIAPGVHFYTLNREVATTAILKQLQLWAAAPRRPLPWRIAANHKRSG
EDVRPIFWASRPKAYIFRTQHWDEFPNGRWGSSESPAFGELKDYYLFYLASKSSKEQLLA
MWGESLESERDVWDVFHAYLTNSCNPKTGKKVTKVPWNDDELSAETALLTEKLADFNKRG
VLTINSQPNVNGASSEDLVVGWGMPGGYVYQKAYLEFFTSKENVDALLNVLPLFPRINYH
IINRSGSADFSNCHKHRSTAVTWGAFPGTEIIQPTIVDPVSFRAWKDEAFGLWEEQWGKL
YPENSKSRSIIQHITNNYYLINLIDNDYPKDSCLWDVLESMFAWRTLRQENVVRISDSVL
RS
>A0A510HEB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacter xylanophilus|TrEMBL
MGLSFRDLLEGRVLVGDGAMGTLLADRGVGYGHPYARANLTHPELVEQLHAEYVRAGAQA
IETNTFSANRVKLAGHRLEERVREINESGARLARRAVEEAGERVLVLGAIGPLGRPLAPV
GNIPREEARALFREQAEALLGGGADALLLETFTDLGELRLAWEAVRDLGAPVLAYKTFVE
DGETLAEGLPERVAREISGWGVELVGSNCTVGPQRMLGIVEQMSAVGPVAAFPNPGLPQL
VEGSVRYSRDVEHFARYGRRLAEAGARFIGGCCGTTPEHIRALSEALRDFRPRKTSVALR
RAPGDLREDDRRDAAGPRSELAKKLLGGGFPVAVEVDLPRGNDLSGVVEAARRLRERGAD
AIDISDGARARLRMHPVAAARIVQERAGIEVVAHMSCRDRNILGLQADLLAAAALGVRNI
LAVTGDPAQIGDYPEATGVFDTDAVGLVHILSRMNRGEDLAGNAIGHAPGFLIGAAFNPT
AEDLDAEVERLRRKLEAGAHAFWTQPVFEMSALERALERLGDTPARILLGLMPLRSARQA
EFLHHEVPGVEIPEEIRGKLAELPPQDAPRYGVEVARNLLARARPLVSGAYIMPPASAPE
LAAEVMEALR
>A0A380THZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|metagenome|TrEMBL
MRAMTDRLRSTTLLSVAAPLPGDVKVSFEFFPPKTAEMEEKLWACITRLATLEPAYVSVT
YGAGGTTRERTHATVVRLRTETALEPAAHLTCVGATRAEIDAIAERYWAAGVRHIVALRG
DPPEGATHYQPHPGGYAYACDLVAGLKRVADFEISVAAYPEMHPEAPSAQFDIDNLKRKI
DAGATRAITQFFFDVDIYFRFLDRCQAAGITVPIIPGILPVTNFGQVVRFAKQCGAAVPA
WMGELFAGLDSDPETRRLIAASVAIEQCRALHAGGVKQFHFYTLNRADLAFAICHVLGVR
PKAEAQAQPTPQARVGDSR
>A0A2N0X1E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychromonas sp. psych-6C06|TrEMBL
MADSILKSKSSDPKQGVYFIGTTPPKQDTDIELVSGIADKLLNRLDEIDYDGLIVYDIQD
ETSRIDKPRPFPFKYTHDSRLYSKLLHDKCHKPVITYKSVSQRDGADFSAWLSDAWHQFS
VRDIVLVGSPSADGEIKLSLNDAYGVLQEHNLDFHLGGVTIAERHVSKGDEHLRLANKVE
KGCEFFISQAVYNAQATIDLLTRYASQCKADGVKPKRIVLTFSPCGSAKTLEFIEWLGIS
VPEATKLRILASDNPLKESLMINRNNFEQILQACLPLDIPFGLNIESLTNRKEEIDAAIL
LFKLLKATLDLKLAESQI
>I3YIJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes finegoldii (strain DSM 17242 / JCM 16770 / CCUG 46020 / CIP 107999 / KCTC 15236 / AHN 2437)|TrEMBL
MNVLDIINTAIAEHRTRFAFELLPPLKGDGMGGVFAAIDRLIGFDPAYINVTFHREGIKQ
SVRPDGGIDWHVVRRRPGTVGISAAIQKKYGVEVVPHLICGGQSKYDIEDALIDLDFLGL
HNVLALRGDKSQNEKFFMPHPQGHSHAVDLVRQIAAMNRGEFVDGEVEECHHSKFSIGVA
GYPEGHEESPSPEADIAALKAKIDAGAGYIVTQLFYDNARFFDFVRRCREAGIAVPIIPG
IKPLSTLRHLTLLPQTFGCRIPEELEREVLRHREDPKAIREVGTEWAVAQSRELKQAGVP
VLHYYPMGKADNIIKIAKAIF
>A0A3B8NU06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MKAGSNLEKVLASGHFACTGEIGPPKSADFHHIDMYAEGMKGKVDAVNFTDNQTAIVRLA
SWGAALRLLYKHGMEPTLQVVCRDRNRLAIQSDLLAAYAHGIRNVLCLSGDHQAFGNHPG
CKGVYDVDSIQLISILRKLRDEGRFECGEECKVAPKFFIGCAVNPFADPFEFRVIRMEKK
IRAGADFVQTQCILDMERFEKFMDLVRKEGLHERVYICAGLMPVKSPRMARYMQTGVPGM
LVSEEFCQRLEKAENPKEEAVNITIDYIKRCQKIEGVHGVHIMAVAWEEIVPTIVEKAGL
LPRPTF
>A0A4P9DBI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E4742|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1J1E2B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfovibrio trichonymphae|TrEMBL
MPGFYSTVDQLCTLSPLFVSVTYGACGSRQRNTLAVTAQLAGRGLTTMAHLTCVGAEPLA
IMQFLKELRAVHVDNVLALRGDSPVDGGQKAEHGHFRHASDLVAFIRAYEPDMGVGVAAY
PAPHPESPSFAADRDHTAQKLRAGADFALTQLFFDVREYEDLLADLHARGLDTPVVPGIL
PIQSFDSLRRVLSLCGANIPGKLYLALEKAQQRGGAEAVRDVGLDFAVRQIRRLLNCGAP
GVHLYTLNKSEMCLYIAEETGLPLNCLSR
>W2ZKQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora parasitica P10297|TrEMBL
MKVIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMAEADIKKALDEAKDAGIQNILALRGDPVRGASS
FDECDRGFSHAVDLVRYIREKYGNHFCIGVAGYPEGHVEIKDKKADIQYLKEKVDAGADF
VITQLFYDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTSFCNTFVPDEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRASESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSNTSTPRERRAMWGEAPAAKEDVRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGALSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
PSIQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEPGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSPATSP
>A0A1V1PPF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|alpha proteobacterium U9-1i|TrEMBL
MSATHAQNLIAEAAEKLGQPRVSFEFFPPKSESLEIQLWEAIRKLERLNPSFVSVTYGAG
GSTRDRTHRTVSRIVSETAMKPAAHLTCVAAGRDEINMVLDAYWGAGIRHLVALRGDPPG
GVSAMFEPHPHGFENAAALVEGARKRHDFEVSVAVHPERHPNSPSWDAELENFKRKLDAG
AARGISQFFFDADVFLRFRDRLTRAGVSAPIVPGIMPVTNFKGVAKMAAGCGATVPSWLA
SLFDGLDDDPETRRLVAAATTAQLCARLSSEGVEDFHFYTLNRADLTLAICRIVGVRMGK
ESAA
>A0A076JD52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium coryneforme|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLIPDFISVTYGTGKQSDRTATARIARTIH
TEYGIPSVAHLTAQYADKEIVDQALDMFDRAGVAAVLPLRGDSVEGRTPAGVFDHASDLV
AYIHAKRPDMTIFGACYPETHPEAASPQADLDNLKIKVDAGASHLISQLFYDNDYFTDFL
GRARGTGIDVPIEAGIMPITNAGQVRHMSEVCAASIPPAVNTILDRWGDDRTSLREAGII
YASQQIADLVSQGVDGIHLYSMNQAGVTRRIWHNVRHLFKVRQASSSMLSL
>A0A4P9IY28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas distincta|TrEMBL
MALSLKEKIVDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQDRPFAFKQTVDPREYSHLLRNLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDL
QNVVLVGSPSSIGDIKLSLPDAYKALAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAKGITPQRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKLIA
>A0A2H5YRP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR26|TrEMBL
MAHPFLERLSRGPILCDGAMGTQLYERGVPLDACFDEVNLSNPSLVVEIHRDYILAGAEI
IETNSFGANRFKLEAHGFAHLVGQINRQAARNAREAREITGQPVLIAGSIGPTGRTLAPI
GTTPPEVVRDAYREQISALLEGGVDLLIIETIFQLEEMRQAVLAAWDVCDLPIVAQMTFA
SDGRTIHGHTPEEVIDTLMELGVTVAGVNCSVGPRPTLDVLRTMLGVSGGRIPLSGQPNA
GWPRQIGNRVIFTASPDYFADYAREAINLGISIIGGCCGTTPAHIQAMRKALDVLEIPDI
RRPPAIEVPRRRPRELLAAEGPTKLAQKLGREFVVSVEIDPPKGLNPHKALAGAQLLKDA
GVEFINVADSPMARVRMSALALCALIQQEVEVETILHFTTRDRNLMGLQSDLIGAHALGV
RNIIALTGDPPTLGNYPQATPVYDVDSIGLVKIIKQFNQGMDAGGASIGQLASFTVAVAC
DPTRPNLDEEIERLHRKIEAGADLVMTQPVFALRVWTDFLRRYEERYGPIPIPVLLGILP
LQSHRHAEFLHNEVPGITLTEEARERMRLAGPEGRREGVRMAQELLLEAREVVHGVYIMP
SFGRYEVAAEVLEVLPDRRLVAAVPGANPSSG
>A0A7Y7XI77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas gingeri|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLADYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLQQYKDAGIQRIVALRGDLPSGMGMASGELLHANDL
VSFIREETGSHFHIEVAAYPEMHPQARSFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTKSIQAFG
EQVISQMCDRLLEGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7X1NQN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter bussei|TrEMBL
MPPPTYPALSYELYPPRNAAAEESLWTSIRRLEDTRPDFVSVTYGAAGSNRETAIHLLRR
LLTETTLRPLAHLTCVGTSRAELTQIVERLIGGGVRGILALRGDAPEGFEAAAGDVEHAD
DLVRLIREVEGRRTAQLAAGRVSVGVAAYATRHPDSPSVEQDIEVLLAKEEAGADFAITQ
VFFTPSDYTRLVTRARRAGVTIPIIPGVMPLTSTRRLKKLAGLAGVDVDETLWAKLDGAR
TDEERRRVGVTATVGLARAALDDGAPGIHLYTFNEHAAALDVLDALDLERPPEAGLAASL
>A0A1M7KNQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gracilibacillus kekensis|TrEMBL
MSGLLTKLNDQIMIADGAMGTLLYAHGVDRCFESYNLTHPEEILNVHQSYLDAGAEVIQT
NTYGANYIKLNRFGLEDNVHQINTKAVQIAKSAAKENAYVLGTIGGIRGVQKLVTSKKEI
IRSFKEQLFSLLLEGVDGLLLETYYDFDEIKQVLEITRQETDLPIIANVSMHEPGVMENG
IALPTALQTLDDIGANVVGVNCHLGPHYMIKALETVPLLQNAYLAAYPNASLPSYQNGKL
VYNQHSNYFKQCAKAFRDQGVRLIGGCCGTTPEHIRALKDGVTHLAPITSKETKPLLTKE
NTSHSQRNNNDSLADKAKKQHTVIVELDAPKHLDIATFMDGVFALEKAGVDAITLADNSL
ATPRISNLAMAVKMKQAGSKVTPLIHLTCRDRNLIGLQSHLMGLHTLNFHEILAITGDPT
RIGGFPGASSVFDVTSFELTRLIKQCNDGLSFSGSSLKTNTNFQVAAAFNPNVANLEKAV
KRMKKKADNGADYFLTQPIFSHERIIELHRLTKDIEQPIFIGIMPLTSHRNAEFLHHEVP
GMKLSDEVRARMQQHNNRQDSLREGIQIAKELIDTTINYFNGVYIITPFMHYPSTVELTK
YVHEKTQLVTKI
>Q93A68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MLIADGAIGTMLALRGVPTPYELANLLYPDTVRALHREYYEAGARLIETNTYTANRVRLF
NLPERGSEAPPTYSLLEQFGSPEELVRRINQEAVRLAREAVGADALVFGSVGPVGKPLEP
IGETRLDEAEGAFREQMQALLEAGVDGLILETFIDPRELELAIRVARELAPDLPLIASKG
FVEDGETLMEGLPERFAHTVSALGVDAVGANCVVGPQRMLDIVRMMATGTELPLSSMPTP
GLPQLVRGQVVYDIHPDYFGRYAVRLVEAGAQIVGGCCGTTPDHIRAVAQAVSRTPVKRR
AGGIRAVVRERKEEELPLAEPSRLSQILGKERVIAVELDLPRGLKVQKVIEGARLLKEHG
VHVIDISDGARARLRMNVIAISHLVQREAGIEVMMHFACRDRNLLAIQADLLGAHALGIR
NVLAITGDPAQIGDYPTATSVFDVDAIGLVRILRRFNEGRDLAGNTIGVRANFTIAVAYN
PLAPDPETERDRLRKKIEEGAHLVYTQPIFEMRVVEETAELMNRLGVPWLVGVLPLRSAR
HAEFMHNEVPGVSIPEPILRRMAEAPEEDALAVGLEIARRFVAEAAPYAQGVYLMPPAGS
AQIALQVIEAIR
>A0A7W2B372|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
MKITDILANAKGCEFTFEILPPLKGQKAQEIFDNIDPLMEFKPPFIDVTYHREETVYKRL
PNGLLQEKVVRKRPGTVGICAALMHRYQTEAVPHVLCGGFTKEDTENVLIDLNFLGIENV
VALRGDQAKGESYFTPKPDGNNYAVDLVKQINDLNQGRYIDEDLQNSMATDFCIGVAGYP
EKHFEAPSLNIDIEHLKAKVEAGADYIVTQLFFDNSKFFAFVDKCREAGITVPIVPGLKP
LVTKRQLSILPQIFHVDIPDTLAIEALKCKDNAQVRQLGIEWCIQQSKELMDAGVPVLHY
YSMGKSKNIYEIAKAIF
>A0A6N9YRF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytoactinopolyspora alkaliphila|TrEMBL
MSQGLPTTTQGRPTTIRELLAAGERSYSFEFFAPKTDAAEVLFWRTIRELERLQPTFVSV
TYGAGGTTRESTVRVTGQLALDTTLTAMGHLTAVNHSVAELRHVIGQYADAGICNILALR
GDPPGNPLGEWEAHPEGFTFTEELVRLVKSVGDFCVGVAAFPEKHPRSPDQAADVRFLVD
KFRAGADFAITQMFFDVDDYLRLRDRVDAAGGTKPIIPGIMPVTNVKQIERFAELSGARF
PDALAERLRAVEDDKDAVRAIGVEVATEMCERLIAEDAPGLHFITLNRSTATREIYQNLG
LGATLTPA
>A0A1W9US09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_35.2|TrEMBL
MASSNFLTRIQEAVLIGDGGMGTLLYEQGVPVDSCFESLNLSHPHLVTAVHQAYRAAGAQ
LLETNTFSANRARLAMLGLEADVHQVNAVGARLARQAATDDSDLFIAGAVGPLVGCDQES
LLSVADQEQMFREQMEGLADGGVDLLLLETFASLAELKLAISVAKKIGLPVVAQMTFFAE
GRTREGLDGAQVSRALDEMARLGDGCAADVVGANCGSGPHDMLAVVRQMGGAVERPISAF
ANSGFPQYVNGRHIYLATPEYFAQRSQEMVVSGVSLVGGCCGTTPEHIAALAQRLKGVRP
VARTLAPLEVEKTKSVESVVTISSARENSPLLKGGGKRLPITVELDPPRGLDCTQVIQRA
RQLAASGVDAINLAENPLARIRMGNLALAARIQDATGVPVIAHVTCRDRNLIGLHSELMG
AHLLGLRHILAVTGDPASVGDGGGATSVFDLNSVGLLELLTALNNGRNLLGADLASCSDF
CIGAAFNPNVANLDGQLRKLDKKIAAGAQFVQTQPVYSTEIVDRMDHALTDISIPAFLGI
LPLVSERNAEFLHNEVPGIVLPDEVRERMRGTSGAQGVAAGMEIAVEMVGARHSQSDGYY
IMPPFGKVELAQELIEVIRAFST
>A0A1Y0G5F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuriferula sp. AH1|TrEMBL
MTARTYSFEFFPPKTPDGMDKLRIVRSQLAELHPKFFSVTFGAGGSTRDHSLAAVLDIQH
AGLEAAPHLSCIGSTRDNIRAILEEYKSHNIRHIVALRGDLPSGMASAGEFRYANELVEF
IRSETGDWFNIEVAAYPEVHPQARSAADDLTNFKRKVDAGANAAITQYFFNADAYFAFVD
DCHKVGIAVPVVPGIMPIGNFSQLARFSDACGAEIPRWMRKKLEGYNDDIDSIRAFGLDV
VTDLCQRLLDNDAPGLHFYTMNQSAATMEIWRRLGL
>A0A3D1TLV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium sp|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVDEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREKRPDLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCESRVPEKLAVLLDKWGSDTALLKEAGIAY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A0D0YDP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus gattii EJB2|TrEMBL
MPHLTSLIATHNGPFHNYEFFPPLTDPGFVNLLDRIRRLTSPPFQAPLAVSVTWGAGGST
AERSLELAQQIVGMGVEVILHLTCTNMPKDKVDSALQRCKDLGISNILALRGDPPREEEY
AINPTSTPDFFKHADDLVRYIRQKHGDYFCIGVAGYPNPHPDSESEEEDFKWFKAKCDAG
ADFIVTQLFYDVDVFSEWVKTCRAKGIDQPIIPGIMPIQNYASFRRLVNLTKCPVPDSIT
SDLQPISSDDAAVKRYGAELATKMVNQIIESGLVPGVHFCTLNLEKSVRTILDNLGWSAT
SKTSASDGVVKNKLIQDDSQVVNGIQINGKAGKTQNPAEDLSISPSEANQLAQLGLISTT
LPPAPKTGLSAQGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKEWGVP
VSTSDLSALFTAYLHSDPNHLTTPFCDLPLSPESHMILPHLLALNSAKVQHWTVGSQPAV
DAAKSEDGVVGWGPRGGYVFQKAFVEFFVTEDEVNRLTKKVGEEGKGLITMYAANRKGAF
RTNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWTEWSLLYPRNTPSRKL
LEGIANEWWLVSLIHHDYKDQDALWRFLLEDLQ
>A0A660TSS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MSKLKEMLKSGNFVVTSEVGPPKGVNIDKLIEDAEMLKDNVVAINVTDNQSAVVRIGSMA
ISHLLAQRGIEPVYQLVTRDRNRIALQSDLLSAWALGIENVLCITGDHPYLGDHQEAKPV
YDLDSVNLVKVVTDLNNGHDMAGNELEGKPNFFHGAVVTPEYDPVDLQIIKMKKKIDVGA
NFFQTQAVYDTKSFEKFMNKVSTFKVPILAGIVVLKSAGMAKFMNNNVAGVFVPDDIIKE
MAETPKGDRKKKAVEISARIIREIKSMCQGIHIMPLGWDDTVPQIIEQADL
>A0A3N7DR50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. KBW08|TrEMBL
MTFDPVRGRSSEGWATRTPSIVDRIASSTGSRIPFSVEFSPPRDADAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSTEELRAMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPEGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
YDTKYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVSAYDAEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGPEENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTPDTSVGTAQAV
>A0A495LK54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 120|TrEMBL
MKVTQHIEDAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQYFIPKQGGNDFAVDLVKQINQLNCGKYLHDVMDIDNKANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVKRHLQVLPQIFRIDLPEDLIHAVDQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>K1Z7S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MKSGSNLEKVLAAGHFSVTAECGPPRGADPEIVRKKAAYVKGNVDACNVTDNQTSVVRMS
SLAGCLLIKEAGIEPLIQMVVRDRNRIALQSDLLGASAMGVRNLLCLSGDHQKFGDDPQA
KNVFDIDSMQFIHMVKSMRDEGTFPSGKKLEGAPQFFIGCAVNPFADPFEIRVPRLKLKV
MAGADFVQTQCIYNMKKFREYMELAKKEGLHEKVKILAGVTPLKSAGMAKFMRKMVAGMD
IPDEVINRISAEPKEKQADKGIEMCIEQIQELKEMEGIAGVHVMAIEWEEKLQEIIGGAG
LLPRPVVD
>A0A1F1SS89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria sp. HMSC31F04|TrEMBL
MTSPSKKLSFEFFPTRTPEGRAKQVITRKQLRQFSPEFFSCTSGAGGSTRDGTMQTIGDI
LAEGTAAAPHLPCIGMTAAEIRELLDTYKEMGVRHIVALRGDIPSGMGAGTSGLRYANEL
VELIKNEYGSHFHIEIAAYPEYHPQARSAEDDLNHFVRKAKAGADSAITQYFYNADAYFR
FLDDVRGRGVDIPIIPGIMPIASFSKLVRFSDTCGAEIPRWLRLKLQSYADDSAAIKALA
LDVVTEMCERLLREGAPSLHFYTLNQAGLVSTICQRLGY
>A0A5Y7A9F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Choleraesuis str. CFSAN000515|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A849RCG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloglobulus sp|TrEMBL
MQSQKKHPQLFSFEFYPPKTEEGAASLQVVHSKLAALNPDFFSVTFGAGGSTRDKTFDTV
VDIQNKGIAAAPHLSCVASTKDNIRAILKSYQDHGISRIVALRGDLPSGMMSAGEFRYAN
ELVEFIRQETGDDFQIHVAAYPEVHPQASSAVEDFKNFKRKVEAGANAAITQYFYNAEAY
FYFVDNCEKNAIDIPIIPGIMPITQYTQLFRFSEMCGADIPRWMRKRLEGFGDDRASIQA
FGLDLVSSLCQRLLDGGAPGLHFYTMNQSAPTLAILENTHR
>A0A0S7C2E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentimicrobium saccharophilum|TrEMBL
MKITEHIANRRGKTLFSFELLPPLKGENFEGISQAIDPLVEFNPVAVDVTYHREEIVYRE
RPDGLIEKRTIRKRPGTVGISAAIKFKYNIDVVPHLICGGFTREETENALIDLYFLGIDN
ILLVRGDNPAGEKVFRAEPGGNYYALELVKQAVNMNRGIYLEEEIINANPTNFCIGVAGY
PEKHAESPNMAADIVHLKEKVDAGADYIVTQMFFDNADFFRFEKACREAGITVPIIPGIK
PLSLKSQLSALPRTFSIDLPEALVREAEKCASNQQVRQLGVEWAISQSRELIRHGVPCLH
FYSMGKSDNIRAIAREVF
>A0A8J6SY76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oligoflexus sp|TrEMBL
MELPKSFREALAKKIPLLFDGATGTELYNRGIFINRCFEDANLSSPALILELHNDYVKAG
AEVISTNSWGANSHKLQKHNLQDETRSINRKAAQLARQAIGDRGFVAGSVGPLGVRIEPW
GPTSFEEAKEAFAEQIRGLKEGGVDLLSLETFGDISELHQAILAAKEVAPELPILAEITV
DIEGNMPFGTPADWAVKKIVEWGVDVAGFNCSVGPQPLLTLVQRMLPEVSIPFIVQPNAG
LPKEVDGRTLYMCTPEYMAEFTKHFLQAGVLYVGGCCGTSPEHIRAMSQSFRHQRAMRTA
EEAGYNHRIEVLSHDDAKHPAPASSCTPVPFAEKSQWSRKIANGEVVTSVELLPPAGVVP
TKILESSARLKEAGVDAVNIPDGPRASARMSAILTAVMIEQKAGIETVLHYTCRDRNLLG
MQSDMLGAHAIGLRNVLLVTGDPPKMGSYPNATGVFDIDAIGLTNMVKRLNGGVDLGARP
IGEPTALSVGVGVNPVHADFEYEMKRFAYKVEAGAEWAITQPVFDLKALYRFLEYIEKHK
IKIPIVAGIWPLMSFRNAQFMNNEVPGVCIPDDIMKKMAEPQTAEDARKVGVEIARGMVA
SLGKDVQGFQVSAPFGRVELALEVLSGVNR
>A0A3R9QG99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edaphobacter aggregans|TrEMBL
MAEVLTNEKVSPVGVARLFSGSTVLCDGAMGTMLYARGIFINRCYDELNLSQPEMVREVH
SEYLQAGAEVIETNTFGANRFRLEHFGFGDKVREINVAGVKLARQCVEQIREKQASEAFV
AGSIGPLGVRLEPLGKVGLDEAREAFAEQISAMVEGGPGVGVDLLVIETLTSLVEAEQAI
RAARSVAPEVPVIVMMTVDEDGNCLDGASAETAATKLTAWGADAIGCNCSAGPATVLSVI
ERMRPLTMLPLAAMPNAGIPRAVEGRTIYLTSPEYMASFTRKLVKAGASFVGGCCGTTPS
YIRAMKSSLRAMDAMETGAQVMEKTSADKTATAEVKNKVAPPPLAQRSKIGSMVARGEFV
RLVEIVPPKGIDCSKELDGAAYLHRLGVDAINVPDSPRASARMSAQSLCVQIQQHVGIET
VLHYTCRDRNVLSIQSDLLGASSIGLKNILCLTGDPPKLGNYPDATAVFDVDAIGLVNVV
RNLNCGLDIGKNSIGGSTGFTIAVAANPGVPDIDQEVRRFAYKVEAGAEYAITQPVFDMR
VLEEFLKRIEGFRIPVIAGIWPLTSLRNAEFMKNDLRVSMPESIMARMAAATSPDAAKAE
GVKIAQEMLEEARPMVQGVQVSAPFGKFPAAAQVLGLV
>A0A7K8G5V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orthonyx spaldingii|TrEMBL
MVNETQHACSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6I5VGL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microlunatus sp. Gsoil 973|TrEMBL
MSVTARAERRASISDLLRGNSRPLFSFELYPPRNEEETQRAWFTVRRLESLAPDFVSVTY
GANGSTRDRTITMTKDIAETTTLRTMAHLTAASQSRDQLRRVIGSYAAAGIRHVLAIRGD
MPGGPLVPWEQHPEGLANATELVAMIRELGDFCIGVAAFPDLHPQTRDADLDARVLKEKA
DAGADFALTQLFFTPARYFELVDRVRSIGCDIPIIPGIQPVTRLAQIERFAELSGAELPP
PVVARLQAAGDDPKRVRKVGVDIATEQASELLAGGAPGVHLYTMNRSLATREVYARLRPE
FDRA
>A0A2S6NUH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus peoriae|TrEMBL
MKPDLRTVLNREIIVGDGAMGTFLYQLGFPVNTSFEELNITSPDVISDVHGQYLSAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
LELARNYEQQIDALLSEGVDGILCETFYSLDEIRIALHSVRKYSDIPVICQFAVDQVGRT
QDGFLVAEAFSVLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAKSFVDLGTRLLGGCCGTTPDHIAAISKALNRLQPPPLASKEALS
KESFQVAEQIADEGERGNGRHTSEPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHALK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYVMTQPVYDHELIAAIAEATRHLEVPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGPEGRAMGVSIAKELLDTAMEYFNGIYFMTP
FMFYEMTAELTSYVWQKSGRVQAPLFRL
>A0A1F8VIB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Curvibacter sp. GWA2_64_110|TrEMBL
MTAPTRLPLSIEFFPPKTPEGVEKLRAVRQQLYALKPEFCSVTYGAGGSTQEGTFAAVRE
ILAEGMDAASHISCIGATRATMRENLATLKAMGVKRLVTLRGDLPSGYGMGGEFQYASDL
VAFIRAETGDDFHIEVAAYPEVHPQAKSPAADLQAFVTKVKAGADSAITQYFYNADAYFR
FVEEADALGVTVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFG
LDVVSELCEQLRAGGAPALHFYSMNQSATTLAICQRLGL
>A0A425XP24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus sp|TrEMBL
MSLTALFNDKTVFSLEVFPPKKDSPKEAILPTLQQLQSINPDFISVTLGAGGSDHYTGTV
SIADLIQNQLNIPAVAHVPGLYQTESQVLNLLDHLSEINVKNILALRGDKIPGKEPVGVF
NHANELVSFVHKNRPDFSIASACYPDCHAEANGFIDDIAHLKEKVDAGADHLISQLFFDN
QSFYDFKEKTEIAGINVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQDSKQA
MKDAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWDATKSVFEAANQKKTEKASNH
>B4RHL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium zucineum (strain HLK1)|TrEMBL
MSPTETALGPVARAGVGGAPRPQVSFEFSPPKTPEAEENLWAAIRRLEPLNPSFVSVTYG
AGGSTRDRTHRTVLRMLAETRLKPAAHLTCVEASREEVDEVIRDYWASGIRHIVALRGDP
PGQMGGVYTPREDGYRNATELTAGIRAIAPFEVSVGLYPHVHPESPSIDHDIDVLKAKID
AGATRAITQFFFDVDGFLRFMDRVRKAGVTIPISPGIMPVTNYAGLKKMAGPIGIELPAW
LGNLFEGLDKDPETRRLIAASVASEMCARLAEEGFGDFHFYTLNRADLTYAICRILGVRE
TDQRSKEAAA
>A0A1E9GAN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC076C08|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLTIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A5J6MIT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypericibacter terrae|TrEMBL
MIRNPALISDRIRVSFEFFPPKTREHEGALWHTIERLTAMQPDFVSVTYGAGGSTQDRTL
ATLRRLAQRTELPAAGHLTCVGKSKAEVDAVARDYWAAGIRRIVALRGDAPAAQGRYAPH
PEGYRDAADLVAGLTRIGDFDISVAAYPESHPDSPSPEADLDNLKRKLDAGARRAITQFF
FEPETYLRFMDRARAAGITAPIIPGILPVTNFRTVQEFAKRCGASIPAWLARTFEGLDED
PATRELIAATVAVDLCLKLQTQGVTDFHIYTLNRAELTLAICHMLGLRSGLQRRRHRSHG
EGMAEQATTA
>A0A2M7MNP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium CG_4_10_14_3_um_filter_37_18|TrEMBL
MKVIEHLLKAKEPLISFEIIPPKRGGDIKSLLHVVDDLSKYNPPFIDITSHGAEIVYEET
PQGIKKKIIRKRPGTLGICALIQNKYNIEAVPHILCKNFTREETEDFLIELNYLGIENVL
AIRGDDNGFVKPVPHGRSANEFAVDLVSQVNAMNNGKYLEENLLDAKATDFCVGVSGYPE
KHFESPNLKLDIKYAKQKIDAGAHYIVTQMFFDNNVYFDYVNACKEEGIDAPIIPGLKIL
SLKSHLTNIPRNFYINIPEALAEEVMSAKPEHVLEIGVNWAAKQAEELLNRDVPSLHFYI
LQNSKPINLLMKKLNLHFKKLVVKK
>A0A5J6Z941|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MSFLKSTYYQDIMNQKLNNLNNKIQCSFEFFPAKSIDLEKKLLSSAVKLSQLQPFFFSVT
YGANSGERKKTYDIVKKIHQKTGIVTAPHLTCVDSTPDELEKIAKFYWENGIRSVFALRG
DSYNTDHPHTMYAYDLVVLLKKIADFDISVAAYPETHPESKSAKFDILNLKKKVNAGANR
AITQFFFNTETYLRFRDNCLKNNINVEIIPGILPIYNFEQLKRFAKMTNVRIPSWMFEIF
HGLNNDLTTQRIIGASIVIDMIKNLSIEGVKNFHFYTLNQSDIVYSICRLFGFSSY
>A0A399Q1J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 91RF|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A399HGC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. YIM 130001|TrEMBL
MALGTASTRTDRAHTVRDLLTTGKTSYSFEFWAPKTAKGERNLWNALRRVEAVQPSFVSV
TYGAGGSTRAGTVKATQQIAADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDADVRHFVD
KCRAGADYAITQMFFDADAYLRLRDRLSAAGCDTPVIPEVMPVTSVRQLERFAELSNAAF
PEHVKERILTAKDDAAAVRSIGIEFATEFCAKLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPTQA
>A0A6A7YNY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas helleri|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMNTARQLATYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKDDLRGLLTQYKGAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDISNFVRKANAGADSAITQYFFNADSYFR
FVERVRAAGVMIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDANSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A2N3QTE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum subsp. globosum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLTEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAF
IRERRPDMKIYGACYPEKHPQADTLDHDIDNLKRKVDAGVTHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDHWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWTNVQDLFA
>A0A3A5QPU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AM44-19|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A5P2B8U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces venezuelae|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTFSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLGDWIAHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSPDWESDTRHFID
KCRAGADYAITQMFFDPEEYLRLRDRVEAAGCATPIIPEMMPVTNVRQLDRLPQLSNAVF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHQA
>A0A816F2M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria magnacalcarata|TrEMBL
MILTHNENRTLSSHFNTYQNDAGAEKISSSRFNNFKRSDSETRLLTAKGCCLESIKYMSL
AEKIHQRIANNDRWYSLEFFPPRTASGAANLIGCFERMAVGQPLFCDITWHPAGDPAGTK
ETSSMMIANTMLNYCSIDTMLHITCYGAKKETMLEYLWRAKEFGIRNLLALRGDPPVGEE
WIPEKSDFRYASDLVKFIREHFDDYFVICVAGYPQGHPDMASYEKDLRYLKEKVDCGADF
IITQLFFQPETFIKFESDCRSIGIQCPIIPGIFPIQAYASLKNIVRLAKLDVPEEILACI
EPIKDNDEAIRNFGVQICVDLCRILLDSGKVHGLHFYTLNREYATIEILRKLDLWLEDPP
LRALPWKKISKNYVRSKENVRPIFWSARPKSYVHRTLNWNEFPNGRWGLSSAPSFGVLTD
YHLFYMKIDATRDALLDEWGHELADEQDVWRMFACYIAGEKNGTDKIVHHFPWKDEDISP
ETNFIHDHLIKYNRKGILTINSQPAVNGKSSTDSIFGWGVKNGYVYQKAYLEFFTSEKNI
PALRAVLKKFPGVNYHFVNKSGEVNETNTDGEQPIALTWGVFAGREIIQPTVVDPISFMI
WKDEAFNLWMECWGKLYEQGSRSYSIIEEISNTYLLVNLVDNDYPQDSCLWALLDAMFEY
QKANSKDNNC
>A0A0C2KPJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter piscinae|TrEMBL
MTTPDISFEFFPPQSLEASFRLWDTVQTLAPLAPRFVSVTYGAGGTTRDLTREAVATLHN
ASGLNVAAHLTCVNATKAETMTIADQFAEAGVREIVALRGDPPKGSAGFEPHPDGYANSV
ELIAALAERDQFSIRVGAYPDRHPEATSARADVDWLKRKLDAGADEALTQFFFEADTFLR
FRDDCAKAGIDTSRITPGILPIENWKGARNFAKRCGATIPAWIDDAFDKAIRDGREDLLA
TALCTELCSDLMDNGVDKLHFYTLNRPELTRDVCFALGITPDVSLENVA
>A0A5M9IMS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas panacis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLATYHPDFFSCTYGAGGSTRDRTINTVLQLE
SEVNIPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISNMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A5T1Y498|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHYLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A7M7GV10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apis mellifera|TrEMBL
MKKTVLKRKTYNQYIDNIRNGYQSKDIEHKIVDLRNKLKNVIDTNTIFCSFEFMRVENND
FYKSFFMEMNKYHPLFYALTWKHMKNEIKNYLSSDICNIFSNNILLHLTSNNLTRNDVKI
ILKKTLDRGIRNIFVLKGDSSNTNSEFPYAVDLVRFIRNQFGEIFSICVAGYPEMHPKSL
SKEMDLIYLKEKVDAGADFIITQIFFEANIFIKFVNDCKQIGINVPIIPGIFPIPNYTSF
QKMAKICNVKIPQIILNDLQCIKDNDEEVRIYGIELLKTIIKDIIASRTTCGFHFFTLNK
PSLSSEICDKLGIFY
>A0A7M7GV10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Honeybee|TrEMBL
MKKTVLKRKTYNQYIDNIRNGYQSKDIEHKIVDLRNKLKNVIDTNTIFCSFEFMRVENND
FYKSFFMEMNKYHPLFYALTWKHMKNEIKNYLSSDICNIFSNNILLHLTSNNLTRNDVKI
ILKKTLDRGIRNIFVLKGDSSNTNSEFPYAVDLVRFIRNQFGEIFSICVAGYPEMHPKSL
SKEMDLIYLKEKVDAGADFIITQIFFEANIFIKFVNDCKQIGINVPIIPGIFPIPNYTSF
QKMAKICNVKIPQIILNDLQCIKDNDEEVRIYGIELLKTIIKDIIASRTTCGFHFFTLNK
PSLSSEICDKLGIFY
>A0A1I6BU60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopseudomonas formosensis|TrEMBL
MNNSNIPVSFEFFPTKTDAGHEKLIAAAHVLAEQKPEFFSVTYGAGGSTRDRTQNTVLQL
DQQVKVPTAPHLSCVGDSKEDLRQLLNEYREAGIHRIVALRGDLPSGMGRASGELRYANE
LVEFIRQETGDHFTIEVAAYPESHPQARNFEVDLENFVRKVKAGANSAITQYFFNADCYF
HFVDRVRKAGVDVPIVPGIMPITNYSSLSRFSDACGAEIPRWIRKQLESYGDDTASIAAF
GTEVISDMCQRLIAGGAPSLHFYTLNQAEPSLAILRNL
>A0A1Y0TN94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6N3HQ20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides distasonis|TrEMBL
MKVIDLIRDSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEFVYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVNNL
LILRGDIKTLEASQQNPELYHDHATDLQQQVNHFNEGIALDGSKIDGIETPFSYGMACYP
EKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNEKYYAFVDRCRAEGITVPIIPGIKP
IVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAKEVGVEWCIQQCKDLIAHGVPSLHF
YTMMASDSVYKIAKEIY
>A0A6J1ZGM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinonyx jubatus|TrEMBL
MVNEPRGDGGPTSRSEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRH
IRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMW
GEELTGEESVFEVFACYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKGEKITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A3M4ZDP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. garcae|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDGKDDLRNLLAQYREAGIKRIVALRGDLPSGMGMASGELRHANDL
VTFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A2S7AB27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A2H3KTI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium branchiophilum|TrEMBL
MKVTDHITAAKGATLFSFEIVPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVN
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFIPTQGGNHYAADLVYQIKQLNQGNYLHGVADNDNKSDFCIGVAGY
PEKHLESPSLTTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEKAREMGITVPIIPGIK
PLAVHRHLQILPQIFRIDLPEELIQAVEQCKNNVAVRQVGIEWAIQQSIELKAAGVPLLH
YYSMGKSENIRQIASKVF
>A0A0D5VAQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia fungorum|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWVEVAGYPEYHPQSRSPRHDLENFAHKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCQRLIDAKVPGLHFYTLNGAAATKAICERLGA
>A0A1G9EIY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium psychrotolerans|TrEMBL
MTETTTTRTRGRRIPFSFELYPPKSEAASTALTHTIDRLAAAGPDFISVTYGANGSSRTS
SLDVLRYILDATGVDPMAHLTCVGSSAAEASRLIREFLDAGVRSFLALRGDPPQGVDEGE
TFLGDLGSAAELVQLIHRVQAERVPYRETVIPGLPGARAVKTEREKVRIAVAAFPNGHPR
SRSTSQDIDTLLAKQAAGANLAITQLFFHADHYLSFIHRAREAGVEFPILPGIMPVTSPN
RLRRILELSGEEEPADLSIQLQVEPTEQGQREIGITHAVGLARELIAGGAPGLHLYAFNQ
HETVLAVLEGCGALPASSPHAATQIKAAQRTAHRPTSTGHTHPVKESA
>A0A2E9TME6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp|TrEMBL
MKRISFEFFPPKTDAGKEKLLATQQKLLAKKPAFFSCTFGAGGSTRDNTRDMVNQLRNQH
GDTAPHLSCIGQSREEILELVNGYKAAGVTRIVALRGDLPSGMGYAQSEIKYADELVQLI
REETGDHFTLEVAAYPEMHPQARSFEDDIAHFKRKVDAGANSGLTQYFYNADAYGYYLDA
LQKIGCDAPVYPGIMPILNVANLVRFSNTCGADIPRWLHSKLNDIKDDDAAVKAFGEEVV
TRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGM
>A0A2E4YKY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp|TrEMBL
MSKRISFEFFPPKTEKGREKLLNTQKNLLAKKPEFFSCTFGAGGSTRDNTRQMVDLLREQ
HADTAPHLSCIGQSRDEIMELVNGYKESGVRRIVALRGDLPSGMGYAQSEVKYADDLVAL
IRQETGDHFHLEVAAYPENHPQSRSFDDDIAHFQRKISAGADSGITQYFYNADAYGYYMD
ELRRRGCDAPVYPGVMPILNVANLFRFSDNCGADIPRWLRSRLDDIRDDEQAVKAFGEEV
VTRLCERLLAMGAPGLHFYTMNQSGPILRVLDNLGL
>A0A1J5K1R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorella thermoacetica|TrEMBL
MVESKMAKILSQGQFLVSGEIGPPKHADPTEIKKHAALLKDYVDAMNLTDNQTAIVRLSS
IAAGVHVLQAGGEPIIQMTVRDRNRIALQSDLLGAYSLGMRNVLCLSGDHQSFGNHPTAK
NVHDVDSLQLIRIVKDLRDEKKFACGEEIKGQEPRFFIGAAANPFADPFEFRVMRLEKKI
NAGADFIQTQCIFDMERFERFMALVRERGLHKRAKIIAGVMPLKSARAAKYMQQSVAGMI
VPDEIVNRMEKASDPKAEGVAICVEQIKHLQSIEGVAGVHIMAVMWEDIIPTIVKEAGLY
PRPKVE
>A0A8D1YQU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MDRPKAKCLPAGQCCPSLGVWALEAGISRSSVPPAISRSSAMVNEPRGNGGPGPRCEGSS
SGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEVTG
YLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLKACSEMGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGQELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMLIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEASDPAP
>A0A5W2LQI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Lattenkamp|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2V5RLS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDILRGDGPTFSFEFFPPKTAEAAEILYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEEEIEAILLRYAKSAIGNVLALGGDRPAGIAYDKSR
DSFQHAIDLVKFIRQFNQSGAHPDHRGFGIGVAGFPEGHPATPNRLLEMDHFKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALVGINIPIIAGIMPITSISGFKRIAALAGGARFPAKLL
RALQRCQNDPEMVRRVGVHFALEQCHDLLDNDVAGIHFYTLNRSDATRVIFDSLGIPCRR
KAQVSTVS
>A0A3V3CKL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Havana|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LSPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>B0V153|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Danio rerio|TrEMBL
MVNQRADVGWHSKSDSSGASNSGESSRESSRCSTPVPDADRTDRLRDKMKRRIESGDHWF
SLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYC
GLESVLHLTCCNQTKEKITDHLNKAKRLGLKNIMALRGDPVGEDWVEEDGGFNFATDLVK
HIRHEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIVTQLFFRAETFLKFV
KDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIKQVIEPIKDNDAAIRNYGIQ
QAVEMCKVLLASGEVSGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAISAHPKRKVE
DVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQM
WGEELMSEESVYEVFTNYITGQTNRSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGVL
TINSQPNINGKASSDAIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYQI
VNVQGRNITNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYE
DESPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWQVIEDMFALLDSSQVPQQEANEL
>A0A4R0DWN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter terrestris|TrEMBL
MTKRVPISFEFFPTKTDVGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFTIEVAAYPEMHPQADSFDKDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A174HMZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Eubacterium] rectale|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNQYNVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>A0A6S5BVV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas veronii|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A173WAB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium adolescentis|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVNEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREKRPNLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCESRVPEKLAVLLDKWGSDTALLKEAGIAY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A024UVZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces invadans|TrEMBL
MGKIIDRLMELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPRDQLREILKNVRAAGIRNILALRGDPPIGSE
RWKPVPGGFHNAVELIRFIREEHGDWFCIAAAGYSEVHSEAWNNPNLPPSDQARQLDMIR
LKEKQDAGADFIITQFFFDVDKLLQWIRDCRQLGISIPILPGYLPIQTHNSFLKFTNWCK
TSVPPQVQEALVSIKNDDAAVKKYGIQLAVDTCKKLIANKLSLHFYTMNLARTVRAVLEG
LHLIERERGLPWGAPIMRNKDGSLEKSIEQVRPIFWSNRASSYIARTSEWDDFPNGRWGD
RTSPAYGELSEYYLAYKRPKVARDQLWGRPQTEEDVWNVFVKFIEGSVKQLPWCEQGLSG
ESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPRLM
QRLVVALADYPNLSYHAFSANGTEYTNSPGPSVTAVTWGVFPGKEIIQPTVVDTASFAAW
KDEAFELWLSQWASAYEPETVSHQLIKVPSIAFASFSAFLETMMPFDGVAHIRQLRPRER
RGQRLHE
>A0A076JLZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium adolescentis|TrEMBL
MHSPIFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVN
EYGIPAVAHLTAQYLDKDDVDEALDLFDQAKVSGVLALRGDRVEGAEPAGVFDHASDLAA
YIREKRPDLKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVSHLISQLFYDNEDFLRFVD
KARAAGIDVPIEAGIMPVMNAKSVLRMSKMCESRVPEKLAVLLDKWGSDTALLKEAGIAY
ASEQICDLAARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A377JXW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter cinaedi|TrEMBL
MFGIEFLPQAISEDMECLKAMIQGARENLGREVDFVLIPSNPINKASVSSLLGAYMLRER
FSMIVDSGFSSVVEFVPTISGAGLDRLQIQSQILSVKYGGFSSVALIGGDNGELDGVKLI
ALAREILGGEVSLVSGSGVKIWEKEIEQRLTQKLQVGVDRIITQPIFSMESAKKCVEHFY
VLQERLGIQAQLSLGVFGIFSAESAYRINESHLGFEIPRSYLKALEQGKVKETFISLWQD
MQGLAREYNVSLYLSTPKHNDLRAYGNELC
>A0A2Y9B1C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jannaschia seohaensis|TrEMBL
MGARIVDEPTDALLQRLFVSQGAVPLGFELFPPRSAELREALWTTVDRLSPVAEAGFSVT
MGAGGSTRAGTHDTAVEVARRSGRPVTAHLTALGLSKDEALGAADALWGAGITRILALRG
DRPRHAPEPLPAGFDHASDLVAALAARHDFEITVAAYPEKHPEAETLDGDIEHLKEKLDA
GAKAAICQFVLDPAAYGRFLETCGRHGIDAPIVPGVMPLEGWTRVRSFAVANGTGVPDWL
DRLFAKGEETPELMPYLSAVATVEHARRLIAYGAPWLHVYAMNRWPLPLALARLLGR
>A0A8H6EPW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dekkera bruxellensis|TrEMBL
MSMKITDKINALDKDEPFFSFEFFPPKTEHGMRNLYARLGRMSLMGPLFVTVTWGAGGTT
AEKSVDLAITCQKELGLTTCLHLTCTNTTKKIIDKALASAKAAGIRNILALRGDPSRTSE
VNKLSKEEAPFQYAVDLVKYIREQYGDYFCIGVAGYPEGHADGFYDESQDPHKDMPFLVE
KINAGADFVLTQLFFDDRSFINFDALLRSQADLKNKEIPVIPGLMPINSYDVFKRATKLA
HATIPDSVLGRFSEEIQCDDDRVKEIGVDIMTEMIEDIHQKTSVHTRGFHFYTLNLEKSI
AQIVNRSSLLSQVVDKKERELEECVSDSSDDEIDDNVTTAKRAAYMNRFKQPTNQIIVED
GKHKDSAAKTLASRQIKRRSSSQFQKIMSISSGHGALGKDATWDDHPNGRFGDTRSPAFG
SSGYGPYGPSLHVTPEKAFELWGQPETMDDVSSVFVNYLSRKVDAIPWNEMSINPETALI
QEPLIILNQHHRFTMSSQPACNCAQSADKIFGWGPAHGYVYQKAYVEMFVSKEDWKKNIL
PKLKGNPDVSYYVGDSKSYFDSSLKAKDTNCVTWGVFPDRQIVQTTVVNEDSFKAWKDEG
FQIWREWMMLYPGNSPSANVLKEVLDGYYLTAIVHHDYPDEDALWDLLVGDTE
>A0A352WBS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MARLLNRLTQGQFVVTVEIDPPRGPDAAKTLEKVRGFADRVDAVNVADCPMANVRMSPIT
LAHLIQRDAGVEAIFHLTCRDRNTIGLQAELLGAAGLGVRNILALRGDEPTRGDHPSATG
VFEIGSSRLIKLASTLNAGSTIGGSGLDCGTDFTIGCVANPNARDLEAEVDRLEAKIAAG
AHFAQTQPVFDLRILEHWLMKVAGRVRIPILYGVMPLRNYEFAVHLNNDVPGITVPEWAV
ERMRVRGPQAGMEMVREFISSASAASEISGIHIFPMNNAARILKVVDIIDELGLRCQRKA
KPIRIETRD
>A0A5P0ZPX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus halodurans|TrEMBL
MVENNHAPTLSFEVFPPNSQVGVENLTDTLDQLKGLNPSFISVTASNHKLNYEETTIDLA
KYVKDKLHCHTMVHMPAAYVTKEDVSSILNRLEKMNIHQVLALRGDIVDGFRPETDFKYA
SDLTKFIKSKKPDFTVTGACYPEVHPESKNRVDDIKHLKDKVDAGCNQLITQLFYDNEQF
YRFQEECEIANINVPILAGIMPIVNRKQALHVIKNCSAHLPKKFTDILDKYQDKPVSLKE
AGIAYAVDQIVDLVTNDVPGIHLYTMNKSDTAKHIFQNTASLFELEPAIEE
>A0A661EA58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKSQRDQPRRFSLEFFPTKTPEGADKVRAVRNQLAQLAPDYFSVTFGAGGSTRDGTIETV
REISDEGAVIVAPHLSCVGSTRQEITDLVEGYRQMGVKNLVALRGDLPSGTGYGGGDFPF
ANDLVTFLREQWGDEFHIEVAAYPEFHPQAESAEADLLNFKRKVAAGADAAITQYFYNAD
AYFGFIDSIEKLGVEIPVVPGIMPITNFTQLARFSDACGAEIPRWIRRKLEAFGDDMAAL
RDFGHEVTLQLCQRLLEQGAPGLHFYSMNRLEPCQRLWTELGLSDPD
>A0A0N0VB59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A0U2UKX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus naphthalenovorans|TrEMBL
MTILLEKGRLNPDHFAVTAELVPPRDWNPRPLVEQAVRYRGYVDAVDLSDNLLAIARLSP
VVGAFFVRQVGVEPIVQINLRDRNRMGIQSDLMGLAAIGVKNITILGGYPAKVGTEPNAK
EVYDLETMELVRYARIFSDEGKLFDGTPMQEPPQFSIGTVENIAGKPIKELIDRLEAKAD
SGTSFVRTQLVFDMDLIGEWMEEARRRGLHERVTIMASILPLRNADHVGKALRIPGVVIP
DSLHARLAASDSSEEGLHIAAELIKQLRQIEGIRGIHIRPIGGAEDSVNKVVQYAGLLQS
STAAASA
>A0A8I6A4C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rattus norvegicus|TrEMBL
MNHQKAGVLPDGHCYTSLGMWASEAGCVGLSVPPSISRNPAMSNEARRSGSPSPRSEGSS
SGSESSKDSSRCSTPSLDPDRHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRF
DRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNYCGLETILHMTCCQQRQEEISG
HLHRAKQLGLKNIMALRGDPVGDHWEAEEGGFSYATDLVKHIRNEFGDYFDICVAGYPKG
HPDAESFEDDLKHLKEKVSAGADFIITQLFFEASSFFSFVKACEDIGISCPILPGIFPIQ
GYTSLRQLVKLSKLEVPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHF
YTLNREVATMEVLKQLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQG
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLS
GEPNRHGYRVTCLPWNDEPLAAETSLMKEELLRVNRLGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFLLDNCLWQVVEDTFELLNRHTTKKEAQAP
>A0A6L6A017|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSLLREKLEFTAEPVFTAEFPSIDGGGMRAVQENAARLAPWFDAVNATDNPAAHAHASNT
TTAIAMKAHGLEPIMQIVCRDKNRLAIESDMMGASLHGITNISLLTGDDVTAGDEPEARR
VFDVDSAQAINIARIMTTGTYLSGRKINPAPDFYIGAVENAAAPPFDYRIQRALKKHRAG
AKFLQLQICYHPDRLEAFCKGVAEVAPDLKLIPTIVLLKGGKGLGFMNDKVPGIDVPVDT
LARVNSASNPSEEVFKLTFELAQHALSLPGVRGLHVTDFRHDDSLESFMIDLGRTPKR
>A0A177IXV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum populi|TrEMBL
MPNSSRHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVNATREEIDAVVQSYWDAGVRHIVALRGDPAEGVG
HTYRPHPGGYAQTCDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFDNEIYLRYLEKVRAAGIDIPIIPGILPVQNFKQAASFARRTGASVPYWLAARF
EGLDNDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
PAAKPEAKAA
>A0A6I3CMK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSPIRTAPSLGAVLAGGGHSFSFELFPPKTDAGEQALWQTVRELEALKPTFVSVTYGAGG
STQDRTVRITKQIAEHTTLLPVAHLTCVDASVEDLRRVIAQYSDAGVNTIMALRGDPIAG
PESRWVQHPGGLQHADELVALVRSLGAFSVGVAAFPEGHPESGDFEEDARVLAAKQDAGA
EFAITQFFFRAEDYERLVTRAAAHGCTMPIVPGLMPVTNVAQIERFAVLSGAQFPSELAD
KFGKIKDDQSAVHELGVEVAADLGGKLLAMGAPGLHFYTLNRSTSTREVYEALGLNEV
>A0A3E5GKC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides faecis|TrEMBL
MRVIDLIHNSEKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFSREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLFWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEDLVKEALKCKNDKEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A9QPD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylacidiphilum infernorum (isolate V4)|TrEMBL
MPWEKRMATLIDRLNESLLIGDGALGTYLYSLGVPRNYCIEELSLSQPYLIEKVHKDYIE
AGAKIIRANTAEANAYHLSFFKLEKKLKEIVSSSIGLAKKALGFKEGWIAGTINPIWVRP
ADPPIDLSTRRTLYEEQISLLLEEGCDLLFFETFTDLSDLLLGLELARNKGAQFLFAFVA
SFEEGKLSSGQSLKEAFSKLREAGALLVGINGASGVQASLHLLEEIEKKETDLLGAYPNA
GKPEFYEGKLTYSASPSYFGQNVLKFVEEGLNLLGGDYGTEPVHVAAMAQAAVGVKPIKR
KLAKIRLRYEVGEKETLPQVEPSLLDRLNIKPVFMVEYDSPKTLSMGKFLEGVKAIEKAG
ADALTLADNSLAILRVSNFAAAIHVRRVSKLIPVLHVACRDRNLLGLQSELMGLGTLGFR
HILALTGDPAKSGDHPGATSVYDLNSVGLIRLLAGLNRGVNAAGKDLKGKTDFIIGCAFN
PNTVQFDAQVRKLEAKLAAGARFVMTQPVFDFELIKKIFNYLKPLGVPVFVGIMPILNYR
NAEFLHNEVPGISIPEKIRSRMKDLEGEKATEAGVEFARELGEEILSHFRAIYLITPFLR
YDISVRLLESLQSKKTA
>A0A0U4H2I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia fonticola|TrEMBL
MSFYHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGGGKPEMYATDLVTLLKDVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAVVG
>A0A3G3E410|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Tennessee|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0B7JRC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bionectria ochroleuca|TrEMBL
MEKITDKIAALPADGSYFSLEFFPPKTEMGFSNLKDRLHRMERALRPLFVNVTWGAGGST
AEKSIELAEWCQKELGVTTCLHLTCTNMSRRLVDKALEDAKKLGIRNILALRGDPPRKDE
YQMPDDQVDDDAEELVWALDLVKYIRKKHGDYFCIGVAAYPEGHADESHPLGQSLEHDLP
YLVDKVAAGADFIMTQLFFDFQAYENFENTLREHPSGVFKTIPILPGLMPIQSYQMIKRT
TKLSHAKVPEDIHSRLDAVKGDDEKVKAIGVDIVSELVEKIKVVKNKTPGPKGFHFYTLN
LEKAVSFIVERTHLIPKIPDEEEAIVDGPPITLQINGDPAGKIRSRFSRRKSSSVASDPH
NRVIVKDGQLSNPEWEASGQEAGLSAETPNTRSNTLAISEGEGVLGREATWDDFPNGRFG
DSRSPAYGEIDGYGVSIHMTPTQAIRLWGHPKSREEINDLFVKHIKGELAAIPWSEEELL
AESSIISNHLMKLNTKGWWTVASQPAVNGLRSSDSTFGWGPANGFVFQKAFVEFFLSSSD
WSVLLEKLKAPAAEGTICFYALNAKGDFVSSNLSTFASSGSAASSDTNAVTWGVFPGKEI
VTPTIIEEVSFRAWSEEAFGIWGEWARVYSRGSESEKLLNGIKDDCWLVNIIHHDFVEQD
ALWDLLMG
>A0A2X2ET59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas luteola|TrEMBL
MTRTTPNVSFEFFPTKTEAGHEKLLNTARQLAGYSPEFFSCTYGAGGSTRDRTLNTVLQL
DSEIRIPTAPHLSCVGDSKAELRDLLIRYREAGITRIVALRGDLPSGMGISGGELRYANE
LVSFIREETGDHFHIEVAAYPEVHPQARNFEADLANFVRKIKAGANGAITQYFFNADSYF
HFVDRACKLGADVPIIPGIMPITNYSSLARFSEACGAEIPRWIRKQLEAYADDVKSIQAF
GQEIVTDMCERLLAGGAPALHFYTLNQAEPSLAIWNNLGFKS
>A0A6J2ENX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zalophus californianus|TrEMBL
MVNEPRGDGGPPPRSEGSSSGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSQEQITGYLHKAKRLGLKNILALRGGVEAALYSLGSCFLEGLFCPYPV
GDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAG
ADFIITQLFFEADTFFHFVKACSEIGVTCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIK
DVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIE
DPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELK
DYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYLSGEPNQHGHKVTCLPWNDEPLA
AETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRET
VGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFM
FWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFE
LLSRPTPERGEEALGSCTVVSLP
>A0A351AG63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MRIRRMLETSEPCFSYEFFPPKTEAGLRKLYGRIEHLSELNPSFVSVTYGAGGGSRQRTV
AMAQHIKKEIGIEVLAHLTCVGHTRAELEELLDELVDVGVENILALRGDRHDEVPEGELL
YARELVALARKRHPHLCIGAACYPETHLESPSPEHDLRWTKEKVDAGVDFLITQLFFQNS
SYSKFAMQANALGIDVPIVPGLMPITNVKQIERFARMCGAQTPAVLFDRLRKWEHDEQAV
MALGMEWAIQQGRELLSFGVPGLHFYTLNSSLATRVVHASLGGRGRWSA
>A0A3K5J1P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKFLALRGDVCNDLEKSKDFSYASDLISF
IRKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKKQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A1S2CNR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sobria|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A2K8UPP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lwoffii|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAADLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A0F2CUC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus cristatus|TrEMBL
MVNRQTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLAE
FISNDLEIPTIAHLPAVYLTKEMVSNILQALDRVGVNQILALRGDIFPDVAPKDDFRYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRT
AGLAYAVDQIVDLVTHDVAGIHLYTMNNAATAYHIYKATHALFNHTPSVQSF
>A0A1S9GRP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium laguerreae|TrEMBL
MALKNEARGRNDIRVSFEFFPPKSEEMEGQLWHAVSQLQDWDPDFVSVTYGAGGTTRAPT
LSTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQ
PHPGGYANAAELVAGMKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQ
FFFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFD
DKPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGFSRRAAKSAGAA
A
>A0A0B5DH94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces nodosus|TrEMBL
MGTSLLDDFSLEMTAKDIAGLEEAHPTIPPGTRINITFLGNEDLPMRLAAARAVKRLGFV
PVPHISARRLKSRGELEQFLAGLKADGTAENVFVVGGDPARAEGPYEDALAVIRTGLLRH
HGVRHAGISGYPEGHPAITGPVLWSALTDKHAALGKELLAGDVITQFGFDVDPVLAWVEE
TRARGMDLPIRIGVPGPAGVRRLTTYAARFGVGTSAAIARKYGFSLTNLMGTAGPDRFLR
ALADGYDAGRHGVVKVHFYTFGGLGATSEWIARFRQEG
>A0A0L7TD37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia iniecta|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGADLVALLREVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPGWMTAMFA
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVAAA
>A0A5M9GQR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus paranthracis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKETAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A381CHI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A081QDV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>E3GIA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium callanderi|TrEMBL
MVNKMSSLLQQTLEAGKFAITAEMAPPKGTDFSHILEIADLLKGRVQGVNVTDYQSAAVK
ASSLAMCVELEKKGLESILQMTGRDRNRIAIQGEMLSAGHFGVKNMLALTGDHTTTGDNP
EAKPVFEMDSVSILQTAEVLMSGQDLAGNELKGAPDFYLGACVTPVFDPIEVQLIKMRNK
IKAGAKFFQTQGVFDIEVMREFKELTKDMDCYVLAGIIPLKSAGMAKFMNRSVPGISVPD
ALIERLTEAEDKAAEGIRIAGEFVAQLKEEGVCDGAHIMAIGAEENVPKILDVAGL
>A0A4V1R2H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces atrinae|TrEMBL
MPVSSPSAAADAACRPRVSFELFPPRNDAAALALGRTIDRLAEADPDFISVTFGAGGTSR
GPSLTVLRYILDHTDVEPMAHLTCVGSSHADANRLVREFLDAGITSFLALRGDPPKGAVD
GDDAIGDLASSAELVQLIHRVQEEREPFGQSRIPGTRASEIRDRPRPERVAVAAFPTGHP
RSRFPSQDIDALLAKEVAGANLAITQLFWYADDYLGFVDRARAAGVTMDILPGIMPVTTP
ARLRRLAELTGVPAPSDLAIALQVEPSEAGQLEIGVDYAARLGSEVLAGGAPGLHLYTFN
RHEAVLSTIDRLTVSTPTRSSLSERIEYTI
>A0A3L9J5C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKP
>A0A812GPC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. B1FIG11|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAATGLVAAPHLTCIDATRDELIDIADDYWNNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAVGA
>A0A536GDZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAELLRTPRYEVLPTDEAADLVAAHVPKEVTITVTASPRRGMPATVLLAVRLAKLGYHAV
PHLSARLIRDAHELGQIVDALKAAGITDIFVVAGDAREPAGQFPDSLSLISALPADHGLL
QIGVTGYPESHPFIHDDVTIQAMWDKRRLATYIVSNMSFDPETVKRWVERVRRRGVQLPI
YLGMAGVADPARLLRLSTKIGVAESARFLRGHPSWVARMFRPGGYEPGRFLSALVPELAS
PDRRVAGLHVFTFNEIEPTERWRREMLSRLS
>A0A433WXD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asaia sp. W19|TrEMBL
MTRPSSRVAIELIPRDAQSLNADLDQVKNLVPGVTTINLPDLLRLPLRSWDGAALAHRQG
FAAIPHIRATDIAPTAPLPCAEQEGIREILVIAGDPPPNDSHPSWPNSSAQIIARYQREA
PHLKVYAAFDPYRRAPWQELDDIKQKRDAGAAGFFTQPLFDKRFFELSASWLENDVVFWG
LSPVIGPKARGYWERVNHVVFPGDFEPSLDANIAFARAILTEIRARGDNAYLMPLRVALD
AYLAPLADLLNT
>A0A6B1AG85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MSDRLREWIEGDGIHLIDGAMGTVLYESGVFVNQCYDELNLTEPDRVLGVHADYVRAGAQ
LIETNTFGANPVKLEPFGLEPSTREINVAAARLARQAAGGRAAVLGAMGPLGIRIEPWGP
TSVDEAAELFGRQVAGLAEGGVDGYMLETFSDLDELLQAVRAVRAVAGAAPVFAQMTFGD
AGHTEYGATIEAAAAALEQAGADVIGLNCSVGPSSMLFGVERMVAATSRPVSAMPNAGLP
RDIGDRKIYLASPEYMARYARRMAEAGARFVGGCCGTSPEHTRLTATLLGTNGPGPARVS
VVPAGETDGRAATEPLPLAGRSALGRRLAGGEFVGAVELTPPHGWDPGELLAGAGRLRDA
GVHTVHIVDGPAHRSRIAALPAAIVIERELGMETVPHYSCRDRNMLGMLSDLLGAAAAGL
RNVFLITGDPPRGGPYDTGGVYDIDSIGLTNVVRQLNLGLDPGGSSIGAPTSFVKGVAVN
PGAVDPEEEIRRFAWKAEAGADFAVTQPIFDPRGFLAFAREIEGFGVPLLVGLWPPLSLE
NAEFLAHEVPGVDVPLDVLERIAGAQARGAEAAAREGLAVAREVLEAVRPHVAGALVSTP
GDEVDRAAAVLAD
>A0A0V8B1G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>A0A8C9EYP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pavo cristatus|TrEMBL
MVNENQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVHGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETSLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPPQQ
>I1JZE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycine max|TrEMBL
MKIIEKIRAASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVQHIRAKYGDYFGITIAGYPEAHPDVIESDGLATPEGYRNDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKVSRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALSDYQFMRPRARDKKLVEEWAVPLKSVEDIYEVRFRLYCLGKLRSNPWSELDGLQ
PETKIINEQLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEK
LDALVDKCKDRTSLTYMAVNKDGSWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFNV
WKDEAFEIWSRGWASLYPEDEASRKLVEEVGGSHFLVSLVDNDYINGDLFAVFADF
>A0A8F8TB54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas nasdae|TrEMBL
MASPAPLNLAEARALLLSPLGPVARAGSNRNEVRVSFEFFPPKSDEAEANLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIITETSLRPAAHLTCVDASREEVDEVIEGYKTIG
VDHIVALRGDPPGASGIGGAYQPRADGYANATELTAAISRIGGFDITVGAYPERHPESPS
IDHDIDVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFNGLK
RMCGSCGASVPDWLAGHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETKAVA
>A0A269TBC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera elsdenii|TrEMBL
MHTNELFAKKTVFSFEVFPPKRDIPVETVYPTLAELSKLHPDFISVTCGAGGTGGNRTVE
VAAHIKALGCETAAHMPCIYLTEEAALQNLKELKEAGIENILALRGDEVPGRERAHAFEH
ASDLVAFIKEKEPDFNVIGACYPEGHTEAKTLAADIRNLKTKVDAGASELISQLFFDNAL
FYRFLERCEIAGINVPIEAGIMPVTNKAQIERMVTMCGATLPIKFQRAIAKYGDTPESMR
DIGIAYAVDQIADLLANGVDGIHVYTMNNPYIAKKIAEAVKTLL
>A0A132E2H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia vietnamiensis|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPAADLQNFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATRTICERLTM
>A0A5F2CSY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira meyeri|TrEMBL
MNQILLEVIPRDVQTLLSEVSFVKNNFSQISGINIPDLLRFETRSWVAASKIQNVFPNVI
PHLRAIDFDLDHSGHIIEFLQKNSISSVVVIKGDPPSDMSQKVYPTTSIKLIKKLKKEMS
SLKVYAAVDQYRSGIKDEFDYIEMKIDAGADGFLTQPFFDLRLIHIFTEKLRGKEVYIGI
SPVTNEKSQSYWESRNRAYFPRDFQLTMDWNVQFAKEVIDYCSKNHFNMYLMPIRIPLET
YLRGIFK
>A0A108T2Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides stercoris|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVSVAAAIQNKYNITVVPHILCSGFSREDTEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEKNGYHHAVELQEQINQFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMETGAEYAVTQLFYDNRKYFDFVERARKAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTNEILKCKNDAEAQQVGIEWCVQQCKELMKHHIPSIHF
YSIGAVDSIKEVAKQIY
>I1KG06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycine max|TrEMBL
MLSTPSSPMASKMCLHFEVIHRMVRTNSSRSKAALPVHATWCNISELNMVTTLALQSLVI
QVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTKI
PADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGINTLHLYTLNMEKSALAILMNLG
LIEETKVSRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCNPS
YGALSDYQFMRPRARDKKLVEEWAVPLKSIEDIYERFRLYCLGKLRSNPWSELDGLQPET
KIINELLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKLDA
LVDKCKDRTSLTYMAVNKDGSWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFNVWKD
EAFEIWSRGWASLYPEGDASRKLVEEVGGSYFLVSLVDNDYINGDLFTVFADF
>A0A559LEG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. cubense|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A1V0YQ64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter nosocomialis|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A6J7C5J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSSSLHHLIADARYEVIPMKNLETQLEHIPAGASVSVTCSPAKGQQPTLDLTSRLADLGH
MAVPHISARLCPDEAEVKRLAEFCRSHGIKEVFLIAGDPEQPAGKYDGVVSFLRDFLSCD
HGLQRIGVTAYPDGHAIIPAQVVHEALHAKQELLKDAGVAGFASTQMCFDLTQWTTWAAA
ERAAGFDLPLHIGVPGVIDRAKLFTMGMRLGIGNSMRFVKKNGGVLGRLFKPGGYDPNKL
IIPLSKRADELNIEGLHLFTFNNVQATAEWQRKMLNRFGG
>R1EDK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emiliania huxleyi|TrEMBL
MKGKTRAVPLATLIADAVASNRFFYSFEYSAARDPRPEDLLRRVARMGDDLRPLWIDLTW
GFGDVGARTVAAARHIQKATGLPVLMHLICTDMTVADLDAALDAALLAGVRAILVMRGYT
QAGCAP
>A0A5X9H3B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAKADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6J6N6M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSILREKLENTSERVFTAEFPSIDGGGMDSVIKNAARLAPWFDAVNATDNPAAHAHTSNT
TTAIAMKMHDLEPIMQIVCRDKNRIAIQADMIGASLHGITNLSLLTGDDVTAGDEPEARR
VFDVDSAQAINMARIMATGTYLSGRKINPAPDFYIGAVENAAAPPFDYRIQRALKKHRAG
AQFLQLQICYHPDRLEAFCKGVAEVAPDLKLIPTIVLMKGAKGLAFMNDKVPGIDVPADV
LARASGASDPAQEVYNLTLELAQHALSLPGVRGLHVTDFRHDETLDLFMNDLGRTPKRQG
>A0A0T7DBW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio coralliirubri|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A735V6K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enteritidis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVCIPSWISLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>Q6MVY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neurospora crassa|TrEMBL
MEKITDKVAALPPDSNYFSLEFFPPKTAMGFANLRDRLERMARGLRPLFVNVTWGAGGST
AQKSLELAEICQRELGLTTCLHLTCTNMSRRLLDKTLEDAKVLGIRNILALRGDPPRAAE
YHDENDPEPTDDEEFSWAADLVRYIKKTHGDYFCIGVAAYPEGHAEEAHPREQSLEHDLP
YLVEKVQAGADFIMTQLFFDIDAYEHFENTLRDHPSGAFKDVIIIPGLMPIQSYQMIKRT
TKLSHAKIPPALMARLDAVKGDDEKVKMEGVAIVSEMIERIKEIKSRTPGPRGFHFYTLN
LEKAVAFIAERTNLIPPGTPDEDESAILPDIPQLRINGSSVPTRSIQDLSTRKGSIGSDP
RDRVIVANQRPSHPDYEASPSEAGLPAEPVNTRANTLAISEGEGVLGREATWDDFPNGRW
GDARSPAYGQIDGYGVSLHVTVPQALQLWGSPKTTEDINKIFIRHLKGELSAIPWSEEGF
NDETEAIRDNLIELNSRGWWSLASQPAVNGLRSDDGTFGWGPENGFVFQKAFVEFFIPSA
DWRVLEAKLKQPDMKDTVCFFATNAAGDFVSTDTINFRARMAAEAEGTAEADHRPHEPST
NAVTWGVFPGKEILTPTIIEEVSFRAWSEEAFGIWSEWAKIYGKGSDTQKLLEDLKEDLW
LVNVIHHDYLEKDGLWKLLSQ
>A0A6J7VBJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTIPSVSFEFFPPKDSEGESRLWEAMMNLRSIAPDFVSVTYGAGGSTRDRTIEITTHITE
RTSIPTVAHLTCVGSTQEEIGEILMRYRDAGIKSILALRGDPPSGPSTPWTHTPGGLDHA
DELVALAAEFGDFTIGVAAFPDGHPASHGNFDQDVNVLLRKEELGASFATTQFFFDVNKW
ISLVNRLKERGSQLPIIPGILPISSVKQLVRMAELGGTPIPDDIHAKFLSIESDDAAVKA
LGIEIATKLCIELLDAGAPGLHFYTMNSSAATREIWENLGLKR
>A0A090WVC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algibacter lectus|TrEMBL
MKVTDHIKQANGKTLFSFEVIPPKKGTNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYID
KGNGLLDKRITRMRPGTVGICASIMHKYQVDAIPHLLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDSMKDEPYFKPVAGGNAFASDLVQQITNLNKGKYLHDDFKVEHNSDFCIGVAGY
PEKHMEAPSLVNDLRRLKEKVDAGADYVVTQMFFDNNKYFEFVDKAREAGINVPIIPGIK
PIAVKRHLQILPQVFKIDLPQNLIDAVEGCKDNKAVRQVGIEFAIQQSKELKAAGVPVLH
YYSMGKSDNVKAIAEALF
>A0A0Y5DGY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A415C8U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIANTIH
GEYGIPAVAHLTALYSDEAKIDEALDMFEAAGVSAVLALRGDYIDGEEPVGRFNHASDLA
AYIHDRKPDLNVFGACYPEGHYSAASLDEDIGNLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGAKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGII
YASDQIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFTVE
>A0A6J6UI53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTNIGESVTYSFEFFPPKDQEGEERLWSAISALEPIAPDFISVTYGAGGSTRDRTIRITS
EITEHTKLPVVAHLTCVGSTRNELIEILERYKAAGIHNILALRGDPTGGPRAPWTPTSGG
LNHADELVSLAAEFGGFTIGVAAFPDGHPASNGDFDKDIQTLLRKEAAGATFATTQFFFE
VDKWQALTDNLAKRGSQLPIIAGILPVTNVSQLNRMSELGGTPIPVSIASAFDALKDKPD
DVRKLGVELATKLCEDLLEAGVPGLHFYTMNTSTATQEIFAQIKDKKRS
>A0A6J2LM08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllostomus discolor|TrEMBL
MVNEPRGNSGPGTHWEGSSCGIESSKDSLKGSSPGLDPERRERLQEKMKRKMESGDKWFS
LEFFPPRMAQGAVNLIAMFDQMGAGGPLFIDVTWRPTQDPGSDKETSSMTIASTAVNYCG
LETMLHMTCLCQSREAVTGHLRKARRLGLKNILALRGDPPGEQWEEEEGEFSHATDLVKH
IRSEFGDYFDICVAGYPKGHPDAVSFEDDLKHLKEKVTAGADFIITQLFFEADTFFLFVD
ACSKIGITCPILPGIFLIQSYHSLRQLMKLSKLEVPQSIRDVIEPIKDNDDAICNYGIDQ
AVSLCRKLLASGLVPGLHFYTLNRLKATTEVLKRLGMWTEEPRRPLPWALSAHPKRREED
VRPIFWASRPKSYIYRTRDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKAPREELLKMW
GEQLSSEKSVFDVFVRYLSGEPNQNGHPVTCLPWNDEPLAAETSLMKEELLRVNRRGVLT
INSQPRVNGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWVERWGKLYDE
KSPSRRIIQHIHDNYFLVNLVDNEFPLDSCLWQVLEDTLELLNRPTSE
>A0A1H2H6C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas yamanorum|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNAESYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A440BP65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVVREFADMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGAMKSAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGVLPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHEAEAT
GSAAA
>A0A820JLI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria sp. Silwood2|TrEMBL
MEFTLSDNQTVSDNQEIYTDEIHCQTAYNLNRFKRIESEGANLGAKGCSLQPVKYVSLTE
KILKRIADNDRWYSLEFFPPRTPSGAANLIGCFDRMAAGQPLFCDITWHPAGDPASNKET
SSMMIANTMLNYCGIDTMLHITCYGAKKAAMLEYLYKAKDCGIRNVLALRGDPPIGEEWD
PAKSDFRYALDLVKFIRQHFGDYFVICVAGYPQGHPDSTSYADDLGYLKEKVDYGADFII
TQLFFQPETFIKFESDCRAIGITCPIIPGILPIQGYSSLRNIVRLAKLDVPKEILACIEP
IKDNDEAIRNFGVQTCLDLCRVLLDSGKVNGLHFYTLNREYATIEILKRVGLWLEEQPLR
ALPWKKTSFSHARSKENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGLSSAPSFGVLADYH
LFYMKLDATRDELLDEWGRELTCEQDVWQMFACYIGGEKNRLNKVVRHFPWTDEELSSET
TLIQKDLVNFNKRGILTINSQPAVNGKPSLDPIVGWGTPNGYVYQKVTITVCNLIADNIP
ALQAVLKNFPSVNYHFVNKSGGVNETNADDEQPIAVTWGVFSGREIIQPTVVDPVSFMIW
KDEAFSLWTERWSKLYEPESRSHEIIDKIANTYFLVNLVDNDYPQGSCLWQVLDSMFEYQ
KLSNKHVDS
>A0A440K468|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A4R9L7B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira stimsonii|TrEMBL
MKKVSEIYGSRKGPVYSFEFFPPKTPEGDVKLMETVKELSQVNPDFVTVTYGAGGSTRDK
TVEIVTEISKNYSVPTVSHFTCVGANQDQIREILQGIRSRGIVNLMALRGDPPRGEGEFR
KTPGGFENATELISFIRSEKMDFCIGGGCYPEKHPSAKSLEEDVRHLKLKVDAGTDFLVS
QLFFMNSAFENFLNLVRKVGIQIPVIPGIMPITSFSQIERFKTLAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFTVKQCRELLEMGVPGIQLYTLNQSHASYDIVRELKG
>A0A833PEE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bereziniae|TrEMBL
MSKRIPISFEFFPTKTDAGAEKLKIVHQELQQFNPEFFSITYGAGGSTRERTLAAIKDFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSADHFKIEVAAYPEMHPQADNSDVDIQHFVEKVKAGANAAITQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLVTYGDDSASIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A6A6WLT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudovirgaria hyperparasitica|TrEMBL
MHISEKLAESREAGKTTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDVTWGAGGRNS
QLTTEMVNVAQSVYGLETCMHLTCTDMEQSKLDEALADAYKAGCTNILALRGDPPREKEK
WEAVQGGFRYARDLVKYIKQKYGNHFDIGVAGYSEGCDDNEDIDELIDHLKEKVDAGGTF
IVTQMFYDVDIFIEWMKKVRAKGITVPIIPGIMPIQTHAAFLRRANWSRCVIPEHWTKVL
EPVKNDDAEVRRIGTGLLAEMCRRLIEAGVSHLHFYTMNLAQATQMVLEELKLIPDVGEK
PLPWRQSLGLNRRDENVRPIFWRNRNHSYIARTQEWDEFPNGRWGDARSPAYGELDSYGI
GLKGTNESNIKLWGHPSSLRDISNLFVKYMQGKLSSLPWSESPITAEADSIKDHLVELNQ
RGIITINSQPAVNGVKSSDPVYGWGPKNGYVYQKGYLEVLISPELIAEVITRIERDPDMT
YYAVNKTGDLKTNAPDDSANAVTWGAFPGKEIVQPTIVETISFLAWKDEFYRLGEDWAHC
YDATSSSRYLIQEVVDTWYLVNIVHNDYHISDGIFPLFSGLEVKDLDKKTFPPPTNGDHT
SNGVEGVNGVQL
>A0A077ZEP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichuris trichiura|TrEMBL
MSLFNNNEVSIDGSASVEPLRPLRERIDHLIKAGDVFFSLEFFPPHSEVGLRNLYRKIER
FAEVGPLFVDITWSVRRDSAGDQPNSSISVARSFRNLFLLDVVVHLTCVNCTTSQLESYV
DKIKNTGIRNIVALRGDTTSKPTLSSMKYANAVQLVQLLRFKHGDYFTIAVAGYPLGHSE
AVSFNEDLKFLKRKVDEGADFIITQFFFSSKSYFHFVKRCRDIGITVPIIPGIMPVHDFE
AFKKTCSMCGQVTPTWMCQMFEPIQENAEAVKNLGIHLAVQMCQELLGHSSYRAPSLHFY
TLNQEEPTRTILKQIGMWQSIDRSILPWKVNPTQAIRRSERVRPIYWKNRPKAYIFRTKH
WILYPDASWLYRSDIQLSDLDGYELFDSLRVVSRKRLLEMWGPNLHTMDDINAIFFSVVS
GRPNVNGAIVEYFPWSESKLKWPILPQPINDDLLWCASNGILLINWQAAVNKAPSGTVDI
DDPSFGWGELGGHVFQKAYLEFFASAAFVHSLLSIIPKYPMVSYHVLNRDASFEKTNAAP
SMVDANVVTWGIFHDNRCVQPYVTHPMAFRQWKDEAFNQWKMWEDLYEARSPEHALFSQI
YDQYSLVSLVDNDYKNPTSLFDLLKEAISEPVKFSVYALLINFF
>A0A7I0JFA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M4B.F.Ca.ET.169.01.1.1|TrEMBL
MTIRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A7K5YC87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pterocles burchelli|TrEMBL
MVNEHQHTCSASSSSKSDGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVLAGADFIITQLFFRSETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGVHFYTLNREVATTEVLKRLGLWTEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWGKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7C7ZJP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MKISKRFQTGKPVISFEFFPPKTDAGFAPLFRSIAELQALDPGFVSVTMGAGGSTRSKTV
DLVIRIQRETGLTAMAHLPCAGFEREQVGTILTQLAEGGVENVLALRGDPPADNADFVQP
QNGFGFANDLIDYTRKQNPELCIVAACYPETHPEARSAQDDLDHAKRKVDAGADVLITQL
FFENARFFSFMDRIRAAGITVPVVPGIMPIVSRAGVKRMTSMCGCEIPSELNAQLEAVGD
DEAATQELGVRWGTMQCRELLDSGAPGLHFYTLNKSSATRQIYENLFPKD
>A0A8H9M7X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes pakistanensis|TrEMBL
MSNKQTLSLEFFPPRDIAAQEKLVRTAKSLMGLNPAYVSMTFGAGGSTRAGTVDAVALLQ
KLGFDVAPHLSCIGTAPEQLSEMLDNYRDQGIRRIVALRGDLPSGMGGDAGELRYASDLV
AFIRQNYGEHFHIEVAAYPEMHPQATGFGDDLGHFVNKVNAGAHGAITQYFFNPDSYFSF
VERAQAQGVTIPITPGIMPITNSSQLLRFSTMCGAEVPRWVRLRLADFGDDRASIRAFGI
DVVARLCQDLLDGGAPGIHMYTLNGAEASMAILPNLTWR
>U7T232|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum CTI-5|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSLEKPDYISVTYGAGGNTKGRTV
EIADRIKRQNGVESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEKGD
FNYARELIEYIHKKKGDKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRK
>A0A5R9CHN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus parafarraginis|TrEMBL
MSLTALFKDKTVFSLEVFPPKKDSPKEAILPTLQQLQAINPDFISVTLGAGGSTHSSGTV
QITDLIQNQLNIPAVAHVPGLYQTKEQVLNLLDHLAENNVKNILALRGDRIPGKEPAGVF
NHANELISFVHEKRPDFSIASACYPDCHAEAASFVDDIAHLRQKVDAGADHLISQLFFDN
QSFYDFKEKTEIAGIHVPIEAGIMPCTNKKQIERIASITGVPLPKKFVAILDRYADSKEA
MRDAGIAFAVDQIIDLVSEGVDGIHLYTMNRADIAERIWDATKSVFAAANSKKQQRASSH
>A0A1K1LIN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. YE71|TrEMBL
MQMKEIFTEGRTVFSMEVFPPKKTDPVSEIYSTLEGLSDTKPDFISCTYGAGGNPADTST
VDICRAIREKFGILPIAHLTCVNNTREDIDRAIALFREAGVTNVLALRGDYSDRVPPKDD
FHYASELITYLKEHAPEISVSAACYPETHPAAVSAVDDILRMKEKEQCGAEHFMSQLFFD
NEDFYEFREKTQIAGIRSPIEAGIMPVTTKAGILRMVSMCGASIPKKLARLLNRYENDPT
ALRDACIAYAIDQIVDLIANDVDGIHLYSMNKPEIAGRIYDAVKNLL
>A0A074KWC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anditalea andensis|TrEMBL
MKITEYLNHAEKPLFSFEILPPLKGQSIKHLMEGISPLMEFNPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFHVEAVPHLLCGGFTKEETENALIDLNFIGVQNV
LALRGDAPKSDGKFVPEPDGHHYSGDLVKQIIGMNKGHYLHEETEVGFQTDFCVGVAGYP
EKHFEAPSMKFDLKHLKAKVEAGAEYIVTQMFFDNKKFFQYVENVRAAGINVPIIPGLKP
ITTLGQIVNLPRTFFLDMPDDLLDELEKCATNEAVKQVGIEWAIQQSKELVANGLPCLHY
YTMSKADATYKIAKAVF
>J9CNE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gut metagenome|TrEMBL
MRVIDLIKSTDRTAFSFEVLPPLKGNGIDKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLYQRARLRRRPGTVAVAAALHNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHEPVFVPDPNGYSHAVELEAQINDFNRGVFVDGSPIKVTNTPFSYGVACYP
EKHDESPNLEQDIYWLKKKIEAGAEYAVTQMFFDNRKFFSFVERVRQEGITVPIIPGIKP
FRKLSQLTMIPKTFKIDLPQELAVEALKCQTDEEATALGIEWCKHQCQELIASGVPSIHF
YSVGAVDSVKEVAKAIY
>A0A6G8S2F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lanii|TrEMBL
MSKRVPISFEFFPTKTDAGAEKLRVVHQELQLLNPEFFSVTYGAGGSTRERTLSAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYASDLVE
FIRNHSGDHFHIEVAAYPEMHPQAESFDIDIKNFAKKVKAGANAALTQFFFNPDAYFYFV
ERIQKEGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKSFGHE
VVVKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>J9BQQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gut metagenome|TrEMBL
MKITEKFDRGEFVVTAEVGPPKGIHIEHILEEAKEYLSGITAVNVTDNQSSVMRLGSLAT
CKALKDEGLTPIFQLTCRDRNRNCSAVR
>A0A829QCD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus 1948|TrEMBL
MTTNPLDRDGPVAELQDPGSIADRLTAVQPGEIAFSVEFMPPRDEAAEARLWRAARVFER
YRPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWVPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPTALEERLLRAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTARG
>A0A6G8PZ91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrobacter marinus|TrEMBL
MQRGVCLLLDLREKLDGRLLVGDGAMGTLLAARGVGYGHPYDRANLTHPQVVRAVHEEYV
RAGARVIETNTFSANATKLALKNLGDRTREINVEGARLARSAVEGALPAGEDAIVLGAVG
PLGRPLAPIGPIRPEEARAVFLEQAEALLEGGADAILLETFVDLAELKIAYDAVASLGVP
VIAHKTFVEDGETLAEGLPGKVARDISSWGAEGLLLPGSNCTVGPQRMLGIAEAMASEVG
PVAAYPNPGLPQLVNGVVRYNQDVGHFAEYGLKLAQAGARIVGGCCGTTPSHVRALAEAL
RDFEPETRSARRVSVSSPELETERAAVEPRTGFARKIKEGFAVAVEVDLPRGHDVSGVVE
AAKALKERGVHAIDISDGARARLRMHPVAVARIVQEQAGIEVVAHMSCRDRNIIGLQADL
LSAAALGVKNILAVTGDPAQIGDYPEATSVFDTDAVGLVHVLSKMNRGEDLAGNPIGEPP
GFLIGASFNPTAEDLDAEVDKLRRKVGAGAHAFWTQPVFELGALERALEKIQDMDVTLLL
GLMPLRSGRQAEFLHHEVPGINIPESVRKKLAELSAEDAPKYGVEVAQNLLAKAKPLVGG
AYLMPPASMPHLAGDVVEAVA
>C7RKF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Accumulibacter phosphatis (strain UW-1)|TrEMBL
MTKDTRTFSLELFPPQTAEGAEKLRATRAQMALLKPRFFSVTFGAGGSTRDRTLETVLDI
QREGHAAAPHLSCIGSTRESIRSILEQYRAHGIRHLVALRGDLPSGMAQPGTFRYANELV
EFIRAATGDWFHIEVAAYPEYHPQARSPLDDLLAFRRKLEAGANSAITQYFYNFDAYAQF
IDQCRRIGIEVPIVPGIMPISSYSSLARFSDNCGAEIPRWIRKKLESYGDDSASIRAFGL
DVVTQLCEKLLASGAPGLHFYTLNQASLTSTLWQRLGLT
>A0A1F0VXH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC072D12|TrEMBL
MSPRLSASAPLDQISEDTPKELKRTALSFEVIPPRHDADAAKIDRLLAMLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTEEELVGWIDTLVDAGVRGLLALR
GDLPEGGMPEGHLPHADSLVRLIRRWESDRVARLAAGRLAVGVACYPNGHAESATPDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTKVLDQLAAATSPEEEKEIGMQITAKLAKSVMNAGADGLHIYTHNNPDITTDLL
HRIGVIP
>A0A0N1DST9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. ERMR1:04|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYRNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERKITRMRPGTLGICSAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEATKGGHESAMDLVHQINDLGRGKYLHDEQACEENNKFCIGVAGY
PEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVTKAREMGITVPIIPGIK
PIATKRHLKLLPQVFKIDLPEDLINEVESAKNNEAVRQIGIEWAINQCRELLDFGVPVLH
FYSMGKSDNIKKVAGELF
>L8MMM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas furukawaii|TrEMBL
MSQDRRYSFEFFPAKTEAGHEKLLATARNLASCKPDFFSCTYGAGGSTRDRTLQTVLQLD
GEIQVPTAPHLSCVGDSKAELRALLAHYKDAGIQRIVALRGDLPSGMGMASGELRHANDL
VAFIRAETGDHFHIEVAAYPEVHPQARNFEEDLKHFVNKVNAGASSAITQYFFNADSYFY
FVERARRQGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVASIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLALWRNLKLPR
>A0A2T3X3S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. Nf4|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAATRLKDYAPDYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQG
>A0A353NE16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MSTETHFNSGSNLEKVLKSGQFAFTGELGPPRGTDVDEVKEKAKFLKGHVDSVNITDNQT
AVVRMSSWAASLIAIQEGLEPNYQMVCRDRNRLAMQADILGGSALGIRNMLCLSGDHQQF
GDHPDARGVFDIDSIQLIAMVKQMRDEGKFLSGNDIHKPPKMFIGAASNPFAEPFVWRVH
RLAKKIEAGADFIQTQCIYNMPKFREFIRMANEEGLTEKVYILGGVTPMKSVGMARYMAT
KVPGMDVPEEIINRLKGVEKSKVAQEGINIACEQIEEFKEMKGVHGVHLMAIEWEHMVPQ
IAEQAKVLPRPVFD
>A0A671QLD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus anshuiensis|TrEMBL
MGSCCVKFCGVICWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPSGDPGSDKETSSMMIAST
AVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAET
FLRFVKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIR
SYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKE
ALLQMWGEELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDALAPETNLLKDELEKVN
RRGILTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPR
VNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQW
VKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFALLDSPRATQEEGSQ
S
>A0A6I9ZN49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinonyx jubatus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEASSGRFSVPPSISRNPAMVNEPRGDGGPTSRSEGSS
SGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCCQSREQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDVCVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMWGEELTGEESVFEVFACYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGEKITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A7J8F9X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Molossus molossus|TrEMBL
MVNEPRGNGGPNPRSEGIGSSKGISGCSSPGLDPKRHERLREKMKRRMESGDKWFSLEFF
PPRNTQGAGSLISEFDQMGAGGPLFIDVTWRPTGDPGSDKETSSMTIASTAVHYCGLETM
LHMTCCCQSQEEITGHLRKAKQLGLKNILALRGDPLGDHWEEEEGGFHYAVDLVKHIRKE
FGDYFDICVAGYPAGHPDAESFAADLKYLKEKVLAGADFIITQLFFEADTFFRFLKACSE
IGITCPILPGIFPIQGYHSLQQLVKLSKLEVPQRIKDVIEPIKGDDEAICNYGIELAVGL
CRELLASGLVPGLHFYTLNRRMATTEVLKRLGMWAEGPRRPLPWAVSAHPKRWEESVRPI
FWASRPKSYIYRTQEWDEFPSGRWGSSSSPAFGELKDYHLFYLRSKAPRGQLLKMWGEEL
TSEESVFDVFVHYLSGEPNQNGCRVTCLPWNDEPLAAETSLMKEELLRANRRGILTINSQ
PNVNGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRKTVEALLQVLKKYESRVTYHIVDVKG
ENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKTHFTMRGRQASPPCTLTSLAS
ASCVPPSSSPGLVLLGTRLHLSPCAGLRSPTYNDS
>A0A0M4GEP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. FJAT-18017|TrEMBL
MTFLEKLQTQILIADGAMGTLLYSYGSDSCFEELNLSHPSQIQTIHKAYIDAGADVIQTN
TYAANYLKLQRYGLEDSVKEINSAAVRNAKKAAQEGIYVLGTMGGNRGVKPQSIAIEEIK
RSFREQLYCLLLEGVDGLLLETFYDLEELETVLAIARKETTLPIIAQVSLQETGILQDRT
PVNEAMKRLDDLGADVVGLNCRLGPHHMLETLEQIELPSGAFLSAYPNASLPAYTDGKFH
YEGDADYFRNSARQFRKEGVRLIGGCCGTTPEHIRAFAAELKAAVPITEKTSVKAGAIVI
EPRQTVRDSPPLHDIVKERPSVIVELDPPRKLDTTKFFEGAKALKKAGIDAITLADNSLA
SVRISNESLGYLVKQELSMRPLIHIACRDRNIIGLQSHLMGLHTLGLHDVLAITGDPARV
GDFPGASSVYDVSSFELIQMIKQLNEGLSYSGKDLGQKTAFSIGAAFNPNVRSLEKAVNR
LEKKIEHGADYFISQPVFSEEKLIEVHEHTKHLDSPIYIGLMPLLNSKNTEFLHNEVPGI
KISQEIRDRMAELTDNPDQAAKEGLAITKSLIDAALELFNGIYLITPFLRYELTAELANY
ANKRANEKRGTIYASTHIH
>A0A7J8FAA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Molossus molossus|TrEMBL
MDQLVPEVPPAGHSCSSLGIWALKAGIVSLSVPPSISRNAAMVNEPRGNGGPNPRSEGIG
SSKGISGCSSPGLDPKRHERLREKMKRRMESGDKWFSLEFFPPRNTQGAGSLISEFDQMG
AGGPLFIDVTWRPTGDPGSDKETSSMTIASTAVHYCGLETMLHMTCCCQSQEEITGHLRK
AKQLGLKNILALRGDPLGDHWEEEEGGFHYAVDLVKHIRKEFGDYFDICVAGYPAGHPDA
ESFAADLKYLKEKVLAGADFIITQLFFEADTFFRFLKACSEIGITCPILPGIFPIQGYHS
LQQLVKLSKLEVPQRIKDVIEPIKGDDEAICNYGIELAVGLCRELLASGLVPGLHFYTLN
RRMATTEVLKRLGMWAEGPRRPLPWAVSAHPKRWEESVRPIFWASRPKSYIYRTQEWDEF
PSGRWGSSSSPAFGELKDYHLFYLRSKAPRGQLLKMWGEELTSEESVFDVFVHYLSGEPN
QNGCRVTCLPWNDEPLAAETSLMKEELLRANRRGILTINSQPNVNGKPSSDPVVGWGPSG
GYVFQKAYLEFFTSRKTVEALLQVLKKYESRVTYHIVDVKGENITNAPELQPNAVTWGIF
PGREIIQPTVVDPVSFMFWKDEAFTLWAEQWGKLYDEESPSRMIIQDIHDNYFLINLVDN
EFPLDNCLWQVVEDTFELLNRPTSQ
>A0A0H3NJY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia enterocolitica subsp. palearctica serotype O:3 (strain DSM 13030 / CIP 106945 / Y11)|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A0L8VRH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces boulardii|TrEMBL
MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRD
AENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDVKLDLEYLKQKID
AGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQH
FSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNIL
PMESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANKCLELWSTPTSINDVAFLVINYLNGNLKCLPWSDIPIN
DEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTK
LPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL
>A0A1Y5U536|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanibacterium hippocampi|TrEMBL
MTPQGLYDPGDPLAPLPGYSSTGRLERVLRSGRFAVTAELNPPDSADPEDVFERARPLAE
VCDAINATDASGANCHMSSIGICSLLSRAGYAAVLQVSCRDRNRIAIQGDLLGAAAMGVS
NVLCLTGDGVGVGDQPGARPVFDFDCMSLLEAARGMRDDGRFLSGRQITKPPRFLLGAAA
NPFVPPYDARADRLAKKIAAGAEFVQTQYCYDLPLLERYMARVRDMGLHERCFILVGVGP
LASARAAKWIRGNVPGIHIPDAVIRRLEGAENQKREGRRICVELIQQIRQIAGVSGVHVM
AYRQEELVSEIILESGVLSGRQPVARRRGRRSEAMREKP
>A0A1W6GK17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium phaseoli Brasil 5|TrEMBL
MALKNEAQARNIGISFEFFPPKSEEMEGQLWNTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRRAGISIPIVPGIMPIQNLTQLKRFAGACGAVIPGFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIRDFHLYTMNRSPLVSAVLDNLGLSRRPAKNAGAAA
>A0A1C5BEK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ncost-T10-10d|TrEMBL
MREFLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVGPSFVSVTYGAGGSTRAGTVKA
TQQIAADSTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDTRHFVDKCRAGADYAITQMFF
NPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLDRFAQLSNASFPSALKERILAAKDDP
AAVRSIGIDFATQFCARLRSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A355BZT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvularcula sp|TrEMBL
MTDLHVSFEFFPPKTEAMQGKLWAAVEKLKPLAPDFVSVTYGAGGSTRERTHDTVARIIK
EAGLPVAAHLTCVAATKAEVDAVLREYWAQGVRHIVALRGDPPGGPGERYIPHPGGYANA
AELASGARKVGAFEISVGCYPEKHPDSPSHAADIDMLKRKIDAGATRGITQFFYDNDAYF
RYLDRVRAAGVAIPIVPGIMPVTNFAGLRKMADTCGTTIPGRLVKLFQNLDDDPSTRLLI
AATVAAEQCLALAEQGVKHFHFYTLNRDDLAYALCMMLGVRPKPAAKAPAQSAGAAA
>A0A7C0UHF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSFKEALESGKFVVTAEVGPPKGTDISEMVHHIELLKGKVEAVNFTDNQSAVMRMNSLAG
CAIAVEHGVEPILQMTCRDRNRIGLQSDLLGAHALGVRSVLCMTGDHVTAGDHKGAKPVY
DVESVQLLRIVDSLNNGKDMAGNELKGGTDFFQGGVVTPEANPLEPQLIKFEKKVKAGAG
FFQTQAVYDIEKFREFMKYARNFNVKVLAGLVVLKSAGMANFLNNYVPGIKVPQELIAEL
KAAGKGKGLDKGIEICARHIRQIRDEGICDGVHIMAIGIEDKVPEIMERAGILD
>A0A7U7J040|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasaccharibacter apium|TrEMBL
MPEVSFEFFPAKTDEKSAALLRVAQRLTAYEPRFMSVTYGAGGSSRERTLETLRQMLARV
STPLAGHLTCVNASRGEVDDVARAYWDNGVKHIVALRGDPPVAKGAAATPYVPHPQGYRY
AADLVAGLKKVAPFEISVAAYPETHPEAESSQSDIDHLKEKFDAGADRAITQFFFNPESF
LRFRDRAVKAGITRPIVPGILPIGRASQAWRFARMCGASVPEELKALFEGVDDLAPIRSR
LSAVVTDRICQRLRDEGVEHFHFYTLNQSAPTSTLCTLLGRQRCHALVENVA
>Q5L228|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus kaustophilus (strain HTA426)|TrEMBL
MGLLDELKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTASVS
VQADRPAPTPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKEQLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACGNDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A6G8IM93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp. BA0156|TrEMBL
MNLPISFEFFPPKTPEGAEKLRAVRQQLYVRQPLFCSVTYGAGGSTQEGTFGTVREILAE
GVDAASHFSCIGATRASVRAQLAQLKAMGVKRLVALRGDLPSGYGLGGEFQYASDLVAFI
RAETGEDFHIEVAAYPEVHPQAKSPEADLKAYVTKVKAGAHSAITQYFYNSDAYFRFVDD
AHRLGAEVPVVPGIMPITSSAQLLRFSDACGAEIPRWIRLRLQAYGDDTASIKAFGLDVV
TDLCDQLRNAGVPGLHFYTMNQSVATLEILRRLDGH
>A0A7V1N0P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MTEKFRDALSDRLLVCDGAIGTMFYSKGVTINRCYEELNIIQPDLVRELHRDYIKAGADI
IETNTFGANRYKLRNFGLEDKVAKINKAGISLAVDEARGGVFVAGSIGPLGISVEPYGKL
TAKLAKNAYIEQGRELIEGGADLVLFETFNDLNELETAITAVKSIDADIPIIAQVAFEAD
GKTKYGATPAQVVATIESLGVDAVGANCSVGPADMLDVVTAMTSVTRLPVVAQPNAGMPK
LVDDRLIYLTTPDYLMTYGKRFIRAGARIIGGCCGTTPEHISVLKGAVRALSPSRVEVSQ
TEEARREEIAETLREDKTPMAKKLAEGKWVQSVELLPPKGPDPSQTLIKAQKLKDGGIDC
INIPDGPRAMARMSPMSLALLFNNKIGIEPILHYTCRDRNLLGMQSDILGAEAVGIRNIL
AITGDPPKLGTYPNATAVYDVDAIGLVKMIKNLNRGLDIVGNQINGKTSIHIGVGVNPAA
VNMDEELRRFKLKVEAGAEYCMTQPVFETDKLFRFLDNIE
>A0A2N2ATR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-6|TrEMBL
MRITELFQRGEFVLTAEVGPPKGVELDHLIKDAHEYLKTRVHALNVTDNQSSVMRTGSLA
TCKVLKDEGLLPIFQITCRDRNRIALQSDVLSAALLGIENLLLLTGDYTTLGDHPQAKPV
FDLDSVSLIHAVKRMEEGFDIAGNAIDGAPPKFAKGAVVSPCSDSVDVQLAKMEAKVKAG
CEYFQTQGVYEPEKFIKFMEQAKQFGVPVQLGLIIPKNVGMCRYMNANVAGVHVPDEMIK
ELQADKEKTKAGDTGVEICARLIKECKDYAQGVHIMSLGWENRIPEILDMAGIAPITPVV
>D2QQZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896)|TrEMBL
MTKITEHIKAANGKPIFSIEVIPPIKGDNLKSLLDNIEPLMEFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFSREETEDFLIDLHYLGID
NALVLRGDPAKPFSTFKAKENGYSYASELVEQVANMNKGIYLHEEDTALAPSNFCIGVAA
YPEKHFEAVDHDIDFQYLKQKVDKGADYIVTQMFFDNAKYLSFVERCRKEGIMVPIIPGL
KPLSTRKHLQILPKLFHLHMPEDLVRAVEACENDQQARQVGVEWCIQQCRELIKAGAPVM
HFYTMGKSDNIMKIAREVF
>A0A1V5WJW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium ADurb.Bin215|TrEMBL
MKIRDILDKRKLSVSFEVFPPRQDSGIEGVMRCTNELAELNPDFISVTYGAGGGTSANTV
RIASHLQTIGVTPIAHLTSYSSTKDEVHRVISELKEKNVYNILALRGDKPRDPDFVPPGD
YRYASDLVTDIKSLGDFCVGGACYPEGHPESGGREQDISNLKAKVDAGCSFLTTQMFFEN
SLLYSFLYRTQAKGITVPVLAGIMPVTSGKQVQRIRELSNAYLPTKFLSLVDRFGDNNDA
MKQAGIAYASEQIIDLVANGVRGIHIYAMNRPDIVRAIMANISSILEGARAL
>W6VR52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM30|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQAVGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>B0Y2U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)|TrEMBL
MEKITDKIAALPPNENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSEE
YNTHGEDDSNKDFTFAVDLVRYIRKMYGDYFCLGVAAYPEGHPVDSYQDVQDPVRDLPYL
VEKTLAGADFIMTQLTYDIDAYTKFEQMLRNHESGAFKTIPIIPGLMPIHSYKILTRTTK
LSHVKIPPQIMSKLEAVKHDDDAVKRIGVDVLSDLVEAIKKIPCPGFRGFHFYTLNLEKT
VSFIIERCGLIPDYPEDSGAVVDDDYTTAPTGAQHRSLSRRRASSVNSLPHNRVIVDRLQ
VPSDGSSRASTHEAPAASAGMPAMPPDRNTTLQISEGQGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHVSGAVARRIWGYPVSREDISALFRRHVSGDLYIVPWSEGGAEENSS
GLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEFF
CPSKDFRTVLKPLFAKHGHEKLAWFATNVKGEFESSLPADPAHADTIEMNPNNVNAVTWG
VFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRVYPRGTPTERLLEEVKNDVWLVCVVG
QDFGAGTENGSEEEQQETKWMWNVLINSQ
>A0A0X3XWW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL WC-3605|TrEMBL
MALGTASIRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVRPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGDWVAHPRGLTYAAELVELIKASGDFCVGVAAFPAMHPRSADRDTDVRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCDTPIIPEIMPIAGVRTLERIPSLTNAAF
PDALRERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHPPQA
>A0A4Q7MS39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobacter ginsenosidimutans|TrEMBL
MKVIDHIKQAKDTLISFEILPPLKGKTINSIYDHLDPLMEFKPAYINVTYHRSEHVFKKK
ADGTFDKVEVRKRPGTVGICAAIMNYYKVDAVPHLICGGFNKRETEDALIDLNFIGVDNV
LVLRGDAAKNETTFEPEIGGNRYALDLLKQVINLNNGIYLEEDIRDGFRTNFCIGVAGYP
EKHFEAPNLQTDLAYLKAKVESGAEYVVTQMFFDNQKYFNFVKACREAGIDIPIIPGLKP
ITSKKQLSVIPRTFHVDIPTDFSNEIMKCKTDTDVEQVGTEWLLQQSKELKAAGVPVLHY
YTLGKPKVIYNAVKKLV
>A0A2E3GYR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomyces sp|TrEMBL
MKSLSQIFASPHPVISIEIFPPKTEKGDRLLYETLDCLTQYQPAFVSCTYGAGGTTRTRT
IDLCLEIQRRYEIPATAHFTCVGSTRDELIEWLTAATANGVQNIMALRGDAPKGEDCFKA
VEGGLSYANELVELIRTLHPNMGIGVAAYPEKHLEAPDMDTDLANLKRKIDAGADASFSQ
LFFVNENFFRFRELYDAQQITIPLVAGIMPITSFDRIKKITAMCGAIFPEELASKLEAVK
DDEEAQLQIGVDHATQQCVELLDQGVAGIHFYALNRSDACKRILENLDLSSRMAAS
>A0A1E7GHP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium S5133MH15|TrEMBL
MKLKDALKKNQFIVTSEVQSPVEDDPEKLIQNLQLIRGRVDGVSVSEIEIDGVVGDTIKT
CDLLKKSNFDPIYQTTTRQKNRLQLQKDLIGAHEAGIENLLVFTEDYRLTGDSLQEMMFF
HVDAGKLSSVLDHLKEGHTVEGDALPEKTEFLLGSGVESSWGKNIPDLEMREMEEMTKIG
TGYFLTTPVFNLDSFEKFIKNVNTFGVPVIAEVLIIRTAGMGQFLNRHMKPGLVPDWVIK
KLSQAPEKQKASIEIFADIVSGLKDICQGVHIISIGGEQRLRQYLDAAKLK
>A0A243ECE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar toumanoffi|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDVAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A142CYD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. JS12|TrEMBL
MGLLDELKQRILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPSINRAAVRLAKQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALIRLEALGADVVGLNCRLGPYHMLRSLEEVPLPNRAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIAAMAKALSDRTPVTEKTVKRRTASVS
VQAERPAPTPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKEQLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACSGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A6I7P6M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geminicoccaceae bacterium|TrEMBL
MTASSVHLSFEIFPPKTAAAADVLHAALADLAALQGRFLSITSGAGGGTPGASAEHAISL
GALARMPARPHLTCVQGSRGEIEATVTAYLDHGITQFVALRGDSPAPDGRYHPRADGFTF
PDALVAALKGWGAADVAVGAYPEVHPEAPDEAACLAYLQAKVDAGADRILTQYCFETDTI
LRWRDRVVAAGIDVPIGVGIMPIGHFPQIKRFSERCGAGVPDWLARRFAGLEPGSPEAHA
VAVEIAAEQCARLVAGGMTHLHVYTLNKSALTLALVRALEAEPLAFRWAA
>A0A7Y8JZB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. P7753|TrEMBL
MAPSSASSLNLAEARALLLSPLGPVARAGSNHNAVNVSFEFFPPKSDEAEANLWSAIRRL
EPLNPAFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIAGYKA
IGVDHIVALRGDPPGGDGIGGAYVPRTDGYANATELSRAINSVGGFDITVGAYPEKHPES
PSIDHDIDVLKAKVDAGATRAVSQFFFDIEAFLRFRDRVRAAGVTLPLIPGIMPVSNFKG
LSRMSAACGAAIPDWLAAHFDGLDEDPETRKLLATSIAAETCARLQEEGFSDFHFYTLNR
AELVYAICRVLGVRETKAVA
>A0A830QQU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium ulcerans|TrEMBL
MSASHIPAAYQRSITEVLKMPSPGRVPFSVEFMPPRDAAAEQRLWKAAEAFHDLGTAFVS
VTYGAGGSSRERTMRVAHKLSKHPLTTLVHLTLVEHTEAELVEILDDYAAHGLSNLLALR
GDPPGTNPMAEWVATPGGLEYASELIELTKKNPKTSHFHVGIASFPEGHYRAPTLEADTE
FTLQKLRAGAEFSITQMFFDIEHFLRLRDRLATADSEHGCKPIIPGLMPITSIRSVRRQM
ELAGASLPRKLEKQLLDAAKGDEESHKEDVREVGIELTTQMAEKLIAEGVPDIHFMTMNY
VRATQEVLHNLGMAPAWGTDHGHDAVR
>A0A8B2XBQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster clostridioformis|TrEMBL
MKTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTRDDVLLILEQLKEQKIENILALRGDRTADREPAGDF
RYAADLVEFIKNHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFRERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFISMMERYGDNPIAM
RDAGIAYAVDQIVDLAAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>A0A8H4PSH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps sinensis|TrEMBL
MDRITDKIAALPDGAEYFSLEFFPPKTAMGFSNLRHRMQRMEQALRPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRRVLDKALEDAKALGIRNILALRGDAPRKEE
YRDADADADDDELTSAVDLVCYIRRNHGDYFCIGVAAYPEGHADESHPVGQSLDHDLPYL
VEKVQAGADFIMTQLFFDIDAYERFEKTLREHPSGAFTSIPIMPGLMPIQGYQMIKRTTK
LSHARMPESIMARLNAVRGDDERVKMVGVDVISEMVEQIRAIKTGDSGHRGFHFYTLNLE
KAVSLIVEKTGLMQQDSSDSDEAVVDDVPLSPLPIIQLNGNAPLRPSSHSRTSRRHSSVG
SDPHNRVIVGNRPLAHPEWEAAGQEAGVPAGGINSRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVRLWGYPATRRDLDDIFVKHMQGQLAAIPWSE
EELMAESSTIKPCLIELNSKSWWTVASQPAINGAPSSDPTFGWGPVNGFVFQKSFVEFFL
PSDDWKALHERLSSPEVRESICFYATNSVGDFASSDSSGGLNSASSWTSTNAVTWGVFPG
KEIVTPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSDSETLLNGIRDDVWLVNIIHHDFV
DTNALWKLLLE
>A0A6C1RND8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MTSPERFRQQIDERVPLLLDGATGTELYNRGVFINRCFEEANLSNPALVLGLHRDYVNAG
SGALLSNSWGANQFKLAGHGLQEKTREINVAAAGLAREAAGEELFVGGSVGPLGRRVEPW
GPLSVEQAFNAFRLQIESLLQGGVDFIYLETFSDLIELEQAIRAAKAAAPALAVAASVTI
NLSGELVHGGSLETAIRSADQWGADIVGLNCSVGPQPTLTAIERIKTLTSRPLCVKPNAG
LPREIDGRMIYMSTPEYVATFTRNFLQTGVLLVGGCCGTTPAHVRNMAQAYRHFMAMHAG
GGTRISVEKPRRQAESEPSTEQQRVAFADKSRWSAKLARGEKVYALELLPPSGVNMAPLL
EKTQKVKQAGLDVINIPDGPRASSRMSTSLAAVMIEQRVGIETILHYTCRDRNLIGMQSD
LLGIHAIGLRNVLLITGDPPKIGNYPNATGVFDVDAIGLTRVAHQLNGGIDVGNRPIGEP
TALSIGVGVNPVHRSFDYEMQRFEQKVAAGAEWAITQPIFDAADMFRFLEYIEKRNIRIP
IIAGIWPLTSLSNAEFMNNEVPGISIPKAVIERMAQARSRQEGMQFGVEIAVQLRRTLDP
AVQGFQISAPFGRIDMALQVAEPLPVEGRK
>A0A229TL03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. KNN50.9b|TrEMBL
MRGRFAEQLSERVLVFDGAMGTVLHVAGNSLDRALPELNLSNPELVSTIHESYVAAGADV
LLTNTFGANRLRLAEHGCSVSPRDINLAAVRLARQARRGVHRTIFVAGAVSPAISSSHRA
GVRADERAEVVREQVQALVDGGVDLLVLETFGYLDELVEAITVTTEVTDLPIVAQATFTS
GGLTPGGETPREVVKTLAALPVTAVGANCTVGPQHMLAILGELKDATDLPVGVHPNAGMP
RRTGRRFSYPVTRAHFGRYARRYAEHGAAMIGGCCGTTPSHIREVVARLADLRPRQANPV
TAVPKPRPAPPQSPLARRLARPGFVLAAQVTPHGEPEDVERVRGADLALVRGNFGEALRL
EREAGVDTITTVTAWDRSLAALQADLLGAHAFGLRTVVCETGTPAPLGDYPGADGVWEVD
SVGLIGLLAGLNAGRDHTGLTLATRTAFHIGARVNPGAEDADAELARTKAKIAAGAQFLI
TRPVYELEGLSRIATELSGVDIPVLVAIAPLTGFAEAEYLAYEVPDVMIPPRALSELEAA
GEREAEVGLALAAELLDGARELVRGAVVVADEHPGNVASLLRQENPAIRL
>A0A1Y4VJA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. An11|TrEMBL
MKIRDYLKEHILLTDGAMGTYFDEKTEGQFLCSEEANLFQPDIIREIHQSYIEAGAVLIR
SNTFSANRKTYEDIMKKHGMPADDAGFVRFVQAGYAIAKETAAEAAKQGRTVFAAADIGP
VYEDSESSEAEMQKEYREIIDAFLEAGADLFVLETFPDTRYVLFMAEYIRQRRPDAFIIG
QFSFVPTGYGRTGFHYKTVLKKAVGSGLLDGAGLNCGIGAAHMERFLRSWLEESGMPKQV
VLTALPNCGYPQIVRGHAVYSDSVSYFGEKAENLAKLGVGILGGCCGTTPEYIREIAVRL
QGSGRKKYPRIRLTTGKQIRQTVTEGNEIMNRRGGKEASGAGVSAGQKAEEAKTAGNSRD
AGERLRHNTFCQKLAKGEPVIAVELDPPFDAQMEKLMNGAHALADTPADIITIADSPLAR
SRADALLTAVKIQQETGIPVMPHLACRDRNRIAIRSGILGAYVNDVRNMLIVTGDPVGRE
EREFTKSVFDFNSIKLMEFLQSLNEELFADAPLCYGGALNQNGARADKIAERMKRKMDAG
CQFFLTQPVYSEEEIDRLAFLQRETGAKILIGIMPLVSYRNALFIKNEMPGIHVPDEVLA
RYSPEGSREEWEQTALTISGQVISMGKDVGAGYYFMTPFHRVSLIQRIMENCLPGSGGAA
GVRAAEESEMCGQ
>A0A7R6Y6W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 131-2-5|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVCRILNETSLTPAAHMTCVDAARHQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A8H4UGV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium zealandicum|TrEMBL
MHIKEMLDTAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRDNEK
WTAAEGGFLYARDLVKHIRQRYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFVRWVKRVRERGVKVPILPGIMPIATYASFLRRANHMKANIPQAWLDAL
EPVKNDDVAVRDIGKTLVAEMCRKLLANGIHHLHFYTMNLAQATRMVLEELEWAPCAERP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTVQDIAQLFVRYLRNEIDSLPWSESPLTSEADEIRDALIE
LNQRGILTVNSQPAVDGVKSSHPVHGWGPSNGYVYQKSYLELLVHPDVFDKMIGRIENHP
DLTFYAVTKDGELRSNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDASSPSRALLAGVMKDWYLVNIVNNDFHQNGTIFELLKGLEVEELTTPATPKSVPE
TNGATNGATNGATNGDAAHEYTTNGAAATAATN
>A0A7W4I0Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. OS31|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLDAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGSGKPDMYATDLVTLLKDVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAA
>A0A525BY31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MNKSNPLLYGITPPKIDHNQEKLARINNKRIERITAGAPDALIVYDIQDEKDRTSDTRPF
PYIETIHPYEYASSDLKALELPKIVYLSVGKYRVEELKTILTNMQQASQPYSIVFVGSPS
SASIGNTSLKEAYSLYQQMKPNIPMGGILIAERHKNTKKEHESLIRKTKAGCTFFVSQCV
YNAGLFKDVLSDYYYTCQDQEIPMQPVYITLTPCGSSKTLDFIRWLGIEVPRWLENDLKR
NKDMLEQSIHHCREIFLETKDFCDRKGIPLGCNIESVAIRRDEVLASFELLKQIRQISS
>A0A1G1H6D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium RBG_19FT_COMBO_58_9|TrEMBL
MSREPRRLKDVLDQGQFAVTIEYNPPKGTNISGVLENAKALVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQMTCRDRNRIAMQSDLMGASMLGIRNILCLTGDYPTVGDHKD
AKPVYDLDSVQVMQLVQGLNNGLDMAGNKLDGATAFSIGAAVTPEADPLGPMLAKFELKV
KAGAQFFQTQAIYHPEQFASFMQAVRPFKAKVLAGILVLRNAKMAEFMNANIPGVSVPQE
MIDELRAAGPAHAEDVGVDIAVRTIKAVRPYCDGVHIMAIKATHRLADIITRAEVG
>A0A2S9V9J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas alba|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPGNENMEKTLWKSVERLAPLKPAYMSVTYGA
NSGERDRTHDVVKRIQQQTGVTAAPHLTCVDASAEELKQIARDYWDSGIRRIVALRGDLP
KGVEKTDMYASDLVALLKDVHDFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTGVFLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKLYEGL
DADDQTTRNLLGANIAMEQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVKPQNGG
>A0A1G1DKB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium RIFCSPLOWO2_01_FULL_39_10|TrEMBL
MKIIEKIKNSDKVLFTLEIVPPEKGYSLKEIFDTIESVKEFSPAVIDVTYHRADYIQVKD
KNGSVIKSMKRKRPGTVGICSAILNKFGIDPIPHIICGGFTKEEIEDMVIDLHFLGIYNL
LLLQGDKLADEPKFIPTKGGYSYAYELVESVSNMNKGLFLGDETIMEEKFDFCIGVAGYP
EKHYAAKSFEEDLKNLKNKVDKGADYVVTQMFFDNQKYFNFVREARRLGISVPIIPGIKP
ITSKKQLKIVPQKFFTDIPVELSKEINSSDDSEKIKEIGIQWCVEQCKELMKNKVPALHF
YTLGKAYPTIDVLRKIF
>D2QYY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pirellula staleyi (strain ATCC 27377 / DSM 6068 / ICPB 4128)|TrEMBL
MPFYPSGKRTLSFELFPPKTTAGETAMYQSIGELMAFQPDVITCTYGAGGSTRDKTLEIT
ASVKQQFGVKVASHLTCVGSTQDQLRDYLRDAISRGVENIVALRGDPPKGETSFQMCEGG
LRYASDLVALIKADFPELGIAVAGYPETHQEAISYADDLANLKRKVDAGGDAIITQLFYD
NADFFRFRDDCDALGITVPIIPGILPVTNLAQIQRITSLCKAKLPSVFVAKLGEQDDTAW
QFQVGVEQATVQVQELLHAGVPGIHFYVLNKSQATSEVLRGIGWSRLETSAS
>A0A0U3JX55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum rubrisubalbicans M1|TrEMBL
MSTPNFSIEFFPPKTAEGAEKLRATRAKLAALQPKYFSVTFGAGGSTQQGTRDTVLEIVG
EGHEAAPHLSCIGSSRASLRAILEDYRANGIKRLVALRGDLPSGYGAMDQASSEFRYANE
LVEFVRAETGDWFHIEVAAYPEMHPQARSPQDDVQNFARKVKAGANSAITQYFYNADAYF
RFVDEAARLGANVPVIAGIMPITNYSQLVRFSDMCGTEIPRWIRLKLASYADDTESIRAF
GLEVVTQLCERLLAGGAPGLHFYSLNQAGPTQAIWQQLVK
>A0A1G6H3D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sanguibacter gelidistatuariae|TrEMBL
MTASDVPPSAPATAHAAPELNAAHIRPPTRQRPTISFELMPPRNPAAAPKFWGTVERLIA
ARPDFVSVTYGAAGGDRDTARTVISRILEHAPVLPIAHLTCVGASRDNVAEVIDEFLAEG
VRSFLALRGDPPRDQPDWRPHPDGVHSSDELVALLREVEATRCASNPSTALRSAARPLTI
AVATFPDGNLAAGTTRTQEVQRLLEKQQAGANFAITQLFYEASTYIDFVTEARAAGVTIP
ILAGLLPMTDPSRLARVESLTGVPAPSALVRELEALDDPAARHALGIRASVELANAVLAA
GAPGLHIYTFNKHEAALDLLEGVHLGGEPVHPGFSGTGSDLASGPWVGASPIPAVLT
>A0A651E5T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
MHIADVYRRGGPAFSFEFFPPKTAKQAERLKQTTRDLVPLKPAAVSVTYGAGGTTRERTH
DLVVDIQKENRLTVVSHLTCVGSTKDEIAGILDRYAESGIENIMALRGDPPDGGAFEPVP
GGFRYASELVAFIKRRYPAMGVGVAGFPEGHPATPNRLQEIDYLKAKVDEGADYVCTQLF
FDNHDFYDWRERCRLAGIHLPLVAGLMPITSRKGLSRMAELAAGSRFPARLLKAIYRAED
DAGVENVGVHWASAQVMDLIENGVDGVHFYTLNKSTATRRIYESLGVHSSDALSSRPV
>G6ER51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus thermophilus CNCM I-1630|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILLALDDMKGSAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVSDTLRELDAVGVNRILALRGDIIPGVEPLKDFRYATD
LIEFIKAEAPNFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIYAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETARHIYEATHSLFKHHSQVGAL
>A0A841JFS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter lappiensis|TrEMBL
MKITDHIKNANGKTLFSFELIPPLKGQSIQGIYNAIDPLMEFKPPFIDVTSLREDYIYKQ
HSNGLLEKLSYRKRPGTIAICAAIMNRYKVDTVPHLLCGGFTRDETENALIELEFLGIEN
VLVLRGDARNSDSSFVPTPNGHAYATDLLQQVVNMNNGVYLHEDYDNIAKTNFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGASFIVTQMFFDNQKYFDFVNNCRANGINVPIIPGLK
PITTSKQLVNLSKTFHIDMPEDLCDAIHACKSEKDVKDMGIEWMINQCKELVKFGVPVLH
FYTMSNAGPTKRIAEAIF
>A0A7G5GVS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma sp. KCTC 72228|TrEMBL
MFLEKIKSAESGVLLYGITPPKVGTTPERVAEIAQKTIERLTTLDIDALVVYDVQDESAR
TKEERPFPFLNALDPLEFASTHLGSLNIPKIIYRPAGKFSPVELSDWLEELHNQNFYPVF
VGVPAPDYPVKTSLPEAYEIWSRHQDTSVIGAVTIPERHNLLKDEDARILDKMSSGVSYF
ISQCIFNLDYAKQVIEDLVISCTEKNISPPTVIFTITACGSAKTLQFMEWLGIHVPDELK
EELKKSDDILEKSVKICLDIASELTTFCMERSIPFGFNIESVAIRKAEIEASISIAEGIG
QMLKDKGVRKVAKDYEAQVVK
>A0A7C1UBW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiothrix sp|TrEMBL
MKKTPLSFEFFPPKTNKGAENLRTVRNELATLNPEYFSVTYGAGGSTQDCTLKTVIEIQQ
ASGIESAPHLSCVGSSQQQIRDILATFKANDIKRIVALRGDLPSGMQDIGEFQYANELVS
FIREETGDYFHIEVAAYPEMHPQALNFEADLNNFAKKIKAGSNSAITQYFYNIDGYFRFV
DSCEKLGLDTPIVPGIMPITNFTQLARFSDATGAEIPRWLRKRLEGYGDDLESIEKLGTD
FVSEMSAKLLEQGVPGLHFYSMNRVEPSMTIWKNINGES
>G7UPC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas spadix (strain BD-a59)|TrEMBL
MIPVSFEFYPPKTEDQRAQLDRTAAKLKKYAPEYVSCTFGAGGSTLSYTAETVRHLQQHH
RFDAAPHLSCVGGSREQIRALLARYRAIGCRRIVALRGDLPSGMGHAGDLRHASDLIALI
RAEHGDAFRLEVGAYPETHPQASDALSDLKHFKAKVDAGADAAITQYFYNADAYFSFVDA
VRAMGVQIPIIPGIMPISNFSQLRRFSEQCGAQIPRWIDKRMAAHGDDAEAIREFGADVV
AQLCQRLVEGGAPALHFYTLNLARPSQLVLKRLGLG
>A0A2B7Z1Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polytolypa hystricis UAMH7299|TrEMBL
MEKISDKIAALPKDANYFSLEFFPPKTQMGSANLQARLERMAQALHPLFVTVTWGAGGST
ASKSLELAEICQRQLGLTTCLHLTCTNMNRSLVDDALEEAKALGIRNILALRGDPPRSKE
YNIDGEDDSNKDFTYAVDLVRYIRRVHGDYFCIGVAAYPEGHSDESYPEDQDPVKDLPYL
IEKTKAGADFIMTQLTYDVEAYTRFETMLRNHESGVFKTIPIITGLMPIQNYRILTRVTK
LSHARIPDEILKRVEEVKADDERVKQIGVDILSQIVTDIKKLPSPGPRGLHFFTLNLEKS
VAFILKRCHLIPPSTEPASDSDSDSETAVFTSSTLQNGPSTADGRTFLISRRRASSLNSQ
PHNRVIVDRPSQTPGGSSQASTTYETMALGAGLPALNPPHRNTALQISEGVGALGREATW
DDFPNGRWGDARSPAFGEIDGYGPSLHATATVAQRLWGFPLSREDINQIFRRHVSGELHA
VPWSEGGAEESTGGLNAETAMIRNDLLKLIDRGWWTLASQPAVNGVRSDDPIFGWGPRGE
GFVFQKAFVEFFCPSHDYQNILKPLLQRHGHDELAWFATNAAGDYESSTTPPTATTTEPN
TGPVDVGFEPGTGLNSSNNGVNAVTWGVFRGKEIITPTIIEEVSFRAWGEEAFRIWDEWK
HIFPRASASEKFIGEMKGDVWLVCVVGQRFGAGGEIGKEDRVEEGNVLWRALAGAGEEGK
SAK
>A0A0H3L8E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea ananatis (strain AJ13355)|TrEMBL
MIYQLTLAGKWFTLSVWTSKRIDVCRLTDNRCGGGSRMSFFHANQREALNQSLAELNGRI
SVSFEFFPPRTSEMEETLWNSIHRLSSLKPSFVSVTYGANSGERDRTHSIIKGIKERTGL
EAAPHLTCIDATRDELQAIAQDYWNNGIRHIVALRGDLPPNSGKPEMYGSDLVSLLKEVG
DFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRAITQFFFDVESYLRFRDRCVSTGI
DVEIVPGILPVSNFKQLQRFAALTNVRVPGWMNAMFAGLDGDPETRKMVGANIAMDMVKI
LSREGVKDFHFYTLNRAEMSYAICHTLGVRPGIAA
>A0A0Q4UTQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. Leaf86|TrEMBL
MPTASHHRASRDGYRPIQVSIEFFPPKTDEMEKVLWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMIKETSLKPAAHLTCVDATREEIDEVVQSYWDAGVRHIVALRGDPQDGVG
TAYRPHPGGYARTSDLVAGIKRIGDFKVSVSAYPEKHPEAATLDADIDALKAKVDAGANQ
AITQFFFENDVYLRYVEKVRAAGIEIPIIPGILPVQNFKQSANFARRTGASVPYWLAARF
EGLDNDVDTRRLIAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKV
AAAKAA
>A0A5C7RHI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiothrix sp|TrEMBL
MTPVLKRSQLPTFSYADEPTPGENLPILPGHVSPGRLERVLRAGHFAVTTEIAPPDSADP
EEVYARAKLFDGYVDAMNATDGSGAHCHMSSVGMCSLLTRKGYAMVMQISCRDRNRIAIQ
GDVLGAAAMGVCNILCLSGDGVQAGDHPEAKPVFDLDSMTALNTIRTMRDESRFLSGRKL
TYPPKVFLGGAANPFAPPFDYRPLRLAKKIAAGAQFVQTQYCFDIGMFKTYMQKVRDLGL
HEQVFILLGVGPLASAKTAEWIRNNVAGVHIPDSIINRLKGAQNQKQEGINICIDMINEA
REIEGVHGVHIMAYRQEHNVAEIVERSGALEGRTPWHPGMYEANHSATQPTTTEDSTV
>A0A522S467|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacteraceae bacterium|TrEMBL
MIPLSLEFFPPKTDEQRAQLERALPKLKALAPEFVSVTFGAGGSTLTQTPLTVQHLRAKH
ALEVAPHVSCMGGSRDEIRTLLANYRALGCTRIIALRGDLPSGMASPGDFRYASELVDFI
RREHDGYFHVEVACYPECHPQSDHAVADMRHFKAKVEAGADGAITQYFFNADAYFRFVDD
ARKAGITIPIVPGVMPISNFAQLRRFSDLCGAEIPRWIGKRMAAFGDDAEAVREFGAEVV
ASMCRRLLAGGAPSLHVYTLNRARATAAVMQRLA
>A0A2D4Y7P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium|TrEMBL
MEAPLFSGLPGDIEVSFEFFPPKSDKMGETLWQSVETLAPLGPRFASVTYGAGGSTRERT
HQQVVRIQNEAGIPAAAHLTCVEATREQVDDVARHYWEEGIRHIVALRGDPPDGQSRYSA
HPGGYANAAELIAGLKKVADFEISVAAYPEVHPDSSDRKADLDNLKAKFDAGATRAITQF
FFEPECFFDFRDQAAAAGIKGEIVPGIMPVMSFAAVQRMSGLCGTAIPHWMEGLFEGLDE
RPEARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKA
>A0A5J6WR04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moritella marina ATCC 15381|TrEMBL
MSFHNAQNIEVLNQSVSELGRDINVSFEFFPPNSPAMTSTLWESINRLKALDPKFVSVTY
GANSGTRDLTHNIIKQIKHETGLIAAPHLTCIDANRQELKQIATDYWDNGIRNIVALRGD
LPPGLNQPDMYAADLVGLLKEVNDFDISVAAYPEVHPEAKNAQADLLALKDKIDAGADRA
ISQFFFDTESFLRFRDRCAAVGIDKEIVPGILPVSNYKTLCKFSKLTNVKVPNWMHSQFE
GLDNDQATRNLVGASIAIDQVKVLSREGVKDFHFYTLNRADLTYAICHTLGVRPK
>A0A357I255|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MPKLSLQQRLQTGAPLFSIEFFPPKTDASAEQLLRTAEALKLYSPDFASITYGAGGSTRS
RTLKYARHLREDYGYEVMPHLTCVGHSRDELRGIIAEFRAAGLGQIMALRGDPPKGESNF
QPHPDGLHYANELVSLIHESYPECTVGVAGYPEIHPEAPSSEDDLSNLKRKVDSGAHFVT
TQLFFDNNKYFDFVDRARQAQIEIPILPGLMCITSREQALRFCDMCGTTIPAELDEQLSA
AGDDSAAVEAVGTNWVFQQARELLERGAPGIHLYILNRKGPAVELMEKLKEAGFYQG
>A0A2D6VK34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MQKPSSITSALRQESPLFSVEFFPPKDDAGGRRMLETAEAIRPYSPNFVSITYGAGGGTR
ETTMRYARILQDEYKFEVMPHLTCVGHTVNELLEILEDFAKAGFRNVMALRGDPPQGEEV
FKATEGGLSYGSDLVELIRENFPDFGIGVGGYPEKHPEAKDNIIDLANLKTKVDAGADFI
TTQLFFDNQVYFDFVKSCKDSGIDIPVLPGLLPVLSLGQVRRFCKMCEASLPTSLEQKLT
QADDENHPAIGAEWAAGQINELLQGGAPGYHIYALNKPQSTLQILQSLGIEKTAA
>A0A2D6KNV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium|TrEMBL
MSPTMDQMREAQRALEAPLFSGLPGDIDVSFEFFPPKNAAMSETLWQSVETLAPLGPRFA
SVTYGAGGSTRERTHQQVVRIQNEARIPAAAHLTCVEATREEVDEVARHYWDEGIRHIVA
LRGDAPDGQSQYAPHPGGYANAVELIAGLKRVADFEISVAAYPEVHPDSPDRQADLDNLK
AKFDAGATRAITQFFFDPQCFFDFRDRAAAAGIDGEIVPGIMPVLSFAAVRRMSGLCGTA
IPPWMEGLFDGLDDRPAARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRAKAGR
>A0A0P9DWJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. A3|TrEMBL
MKPDLREALRRQVLVGDGAMGTYLYQMGFPVGISYEELNLLEPDVIVDVHRRYYEAGARL
IETNTFSANREKLSKYGLEQEMEAINRAGVELARKAVGDDAYVVGAIGSIRAGKRKNVRT
AKVKEDFRDQIEVLVDTSVDGLLLESFYDLEEMLIALKLIRKVSELPVICQFATEGTGST
HDGILLTEAFRKLTAAGADVVGFNCRSGPNGLMRSLQRVAGMEGAPPFSVFPNAGIADYV
DGRYTYAATPQYFGETARKFVDLGARIVGGCCGTTPEHIAAMAQSLQNYAPDPDALRLLQ
EVGEGSETGRIVTRLQPVPSPSAPEPNLAELAKERYTVIVELDPPRDLDIEKFMQGAQAL
KNAGVDALTMADNSLAVTRMSNLALGSLVKERIGMKPLIHIACRDRNMIGTQSHMMGLHA
LGIDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKSLKKKANFVVG
AAFNPNVKHLDKAVQRLERKIESGADYIMTQPVYNAELIEKVYEATKHLDVPIFIGIMPL
ASGGNAEYLHNEVPGIQLSDEVRQRMSGLKGEEGRAMGVQIAKELLDAAMRYFKGIYLMT
PFLAYEMTVQLTEYVWEKAHRLDSHLYPLSK
>A0A6I9WM91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pogonomyrmex barbatus|TrEMBL
MRNLIFEENMCEMSDTDENDNGDDRSVRYDFRTVNPHQTIVNLRQSLRDKISKNEMFYSF
EIVSTRKPGAFYRRLLIDMEEYSPLFYALTWHNEAASSKDSYLPLDLVKNFPSNTLLHLA
AKGLKRDEVLLILRKALAFGIINIFALQGDSLSENGDFEHAADLVAFIRKQFGDTFCVCV
AGYPQMHPESPSKELDLHYLKAKVEAGANFIITQICFESQVLINFVRDCREIGIQIPILF
GILAPASYACLEKMANICKLEVPIKIKNDLAQMKDDDEAAKKYSVDLIVQIITDVIRSGT
TCGFHLFTLNRLSLVAEICKRVKYLKTENPQQKSVML
>A0A844KKK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia faecis|TrEMBL
MKISDACNHKKSLSFEIFPPKKDSELKNIDATLDVLCELQPDFISVTFGAGGSLNCNRTI
ELAKKIKQNYHVEPVVHLTCLHYNRAEIDEFARILTAEGIQNVLALRGDRNPDLTEKDDF
KHASDLISYLKPKGDFCFLGACYPECHPESANKIEEIRHLKEKVNAGAEVLLSQLFFDNT
QFYRFVEDCRIADINVPIVPGIMPVINAAQIKRMITMCGASFPERFQKIIHKFEDNKAAL
FDAGMSYALSQIIDLLANDTDGIHLYTMNNPVVARKICEGIQHII
>A0A8B6KXS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia enterocolitica subsp. enterocolitica|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDIGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A2A3LI41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium NML93-0399|TrEMBL
MLPISFEFYPPKTDEQRRQLDRTAKKLAVHAPEYVSCTFGAGGSTLSHTPETVRRLKQQH
GFEAAPHLSCVGGSREEIRELLKLYRAIGVRRLVALRGDLPSGMGQAGDLRYASDLVAFI
RGEFGAQFHIEVGCYPEVHPQADDARVDLRNFKSKVDAGADAAITQYFYNADAYFHFVDS
ARKAGVTVPIVPGIMPISNFGQLRRFSEACGAEIPRWMQRSMAAHGDDVDAIRELGADIV
TRLCERLVAGGAPALHFYTLNLARPTQAVLARLS
>C7Z4M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium vanettenii (strain ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL 45880 / 77-13-4)|TrEMBL
MHIKEMLTDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRDQDK
WTAADGGFQYARDLVKHIRSTYGNHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKKVRDRGVNVPILPGIMPIATYASFLRRANHMKAKIPQAWLDAL
EPVKNDDVAVRDIGKSLVAEMCRKLLANGIHHLHFYTMNLAQATRMVLEELNWAPSAERP
LQHALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTVQDIAQLFVRYLRNEIDSLPWSESPLTSEADEIRDDLVE
LNKRGLLTVNSQPAVNGVKSSHAVHGWGPSNGYVYQKSYLELLVHPDVFNDMIGRIENHP
DLTFYAVTKDGELRSNAPSDCPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDANSPSRALIDEVMNEWYLVNIVNNDFHQNATIFELLKGLEVKDLTTPATPKSEPE
ANGAEPVANGATAPGAVN
>A0A135IK84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter inhibens|TrEMBL
MTTPDISFEFFPPQSLEASFRLWDTVQTLAPLAPRFVSVTYGAGGTTRDLTREAVATLHN
SSGLNVAAHLTCVNATKAETLAIADQFAEAGVREIVALRGDPPKGAAGFEPHPKGYANSV
ELIAALAERDQFSIRVGAYPDRHPEATSARADVDWLKRKLDAGADEALTQFFFEADTFLR
FRDDCAKAGIDTSRITPGILPIENWKGARNFAKRCGTTIPAWIDDAFDKAIRDGREDLLA
TALCTELCSDLMDNGVDKLHFYTLNRPELTRDVCFALGITPDVSLENVA
>A0A0R1HUB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schleiferilactobacillus kimchicus JCM 15530|TrEMBL
MKVVDCFKDRPVISFEVFPPRPGASEAALNRFYSSLDVLADLDPAYISVTYGAGGSDNHA
STLRLCRYIKAHYGVETVPHLPGLEFTAETLPDYLDALTHAGVENVLALRGDLPATGQPH
GPFQHASDLVTAVKAAGDFNIIGACYPDVHPEAPSLAVDVAHLKEKVAAGTSQLITQLFF
ENDHFYHFLDAVAEAGIAVPIQAGIMPVITAHMVERMATMCGVGLPQKFAKMMRHYADNK
VALRDAGVAYAVDQIVDLLSEGVDGIHLYTMDNPIVTKRICSAIKTLI
>A0A0F2NAF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium BRH_c16a|TrEMBL
MKSGSNLEKVLAAGHFSVTAECGPPRGADPEIVRKKAAFVRGNVDACNVTDNQTSVVRMS
SLAGCLLIKEEGIEPLIQMVVRDRNRIALQSDLLGASAMGVRNLLCLSGDHQKFGDDPQA
KNVFDIDSMQFIHLVKSMRDDGTFPSGKKLEGAPLFFIGCAVNPFADPFEIRVPRLKLKI
AAGADFVQTQCIYNMKKFKEYMELAKKEGLHEKVKILAGVTPLKSAGMAKFMRKMVAGMD
IPDEVINRISAEPKEKQAEKGIEMCIEQIQELREMEGIAGVHVMAIEWEEKLQEIIGGAG
LLPRPVVE
>A0A179G204|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pochonia chlamydosporia 170|TrEMBL
MHIKQMLVDAEKDGQPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGMEKVNDALQRAYKAGCTNILALRGDPPRAQEK
WTATEGGFQYARDLVKHIRATYGDHFDIGVAGYPEGCDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGKVRERGITIPILPGIMPIATYASFLRRAKHMQCKVPDEWMTAL
EPVKNDDVAVREIGKTLVAEMCRKLLANGIHHLHFYTMNLAQATRMVLEELTWAPCAERP
LQHALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPQTVQEIAQIFVKYLNQEIESLPWSEAPLTGEADAIKDNLIE
LNKRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPASIFTEMVKRIEDRP
TLTYYAVTKDGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGTDW
AHCFDSDTPSRVLLDQIMNEWYLVNVVNNDFHENQAVFDLFEGLEVKGLDTPVIV
>A0A059EF15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp. L-53-1-40|TrEMBL
MSSLVTPRQAGSPSVSFEFFPPKSEAMADRLWETVERLEPMTPNFVSVTYGAGGSTRERT
HDTVRRIAQQTHLRPAGHLTCVSATKDEVLSVAEDYWDAGVRHIVALRGDPPSGMGEKFE
QHPGGFRDSIDLIEGIRAHRPDLGRCFEISVSCYPELHPESQGWDAEIAFLKAKQDAGAD
RAITQFFFEPDIYVNFLEKARAGGVTMPIVPGIMLQPNFKGLKRISNLCGASLPAWLHEL
YDGLEEDQETRELVTANVAADLCRKLSDEGVSDFHFYTLNRAGLALSTCRLLGLKPKPVE
AA
>S4HBP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis JCP7275|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIHSKRPDLPILWACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKSGINVPIEAGVMPVVNANQVKRMTKMCSSKISEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A3D0V797|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp|TrEMBL
MFPTRIEIIPSTGIIDQVQALVPLTTTLTMTCLPHHGIERTMRTSVELSTLGYTVIPHLA
ARSINDRAELTRIMRECDVAGIGEVFVIGGDRKQPAGPYGSALPLLEDIAQYTGGRMRAG
VAGYPEGHPTVAALDLLDALQDKQHLATHLVTQMCFDAPKILDYAALLRREGVDLPVWAG
VAGSVPRTKLVALATQIGVGSSLKFLRRKGPLARKLLSGDRYSPHALVAGLESQPGIAGI
HLYSFNNLDAVPDEAGPASSPTALQPALIRGAAREH
>A0A1N7FDV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius nanhaiticus|TrEMBL
MPAPNVSFEFFPPKSLEASFRLWDTVHTLAPLQPRFVSVTYGAGGTTRELTREAVGTLHG
ATGLNVAAHLTCVNASRAETMAIADEFQAAGVREIVALRGDAPKGSGGFTPHPEGFANSC
ELIAALKERDQFTIRVGAYPEVHPEAADENADIDYLKRKFDAGADEAITQFFFDADTFLR
FRDRCAAAGIDKPVIPGIFPIENWSGARRFALSCGTSVPEWLDNAFATAERDGRSDLLAT
AHATEMCSKLMDHGVKDLHFYTLNKPELTRDICHALGVTPKVELRDVA
>A0A2W6BUG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MGLGAASVMPGKQASVADLINAPRRSFSFEFFPPKTDAGETTLWQTIRELESLSPSFVSI
TYGAGGSSRDRTVTLTGRIAAETTLLPMAHLTAVNHSIAQLRNVIGHYADVGVRNVLALR
GDPPGNPAGEWVEHPEGLRYAHELVELIANSGDFVVGAAAFPDVHPRSLDFASDVKHFIA
KCRAGAQFAITQFFFDWQRYTRLRDAVVRAGCDVPIVPGVMPVTNVRQIERMAELSGAAF
PPELARQLHAVEHDPAAVEAIGVDVATALSQRLLAEGAPGLHFITLNRSPATRQVWRRLH
PS
>A0A2M9ZC31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira wolffii|TrEMBL
MKKILEIYKEARGPVYSFEFFPPKTEEGEEKLFEAVGELSKVDPGFITVTYGAGGSTRDK
TIRLTSELAKKYSLPAAAHFTCVGGNRDEIRTILAQIYDSGIRNLMALRGDPPKGEGRFR
KVEGGFGHANELISFIREEGFDFCMGGACYPEKHPEASSLEEDVDRLKDKVEAGASYLVS
QLFFLNSSFGAFLDLVHKKGIHVPVIPGIMPITSFSQIERFKSMAACEFPPRLISDLEAV
KDNPSEFYKRSVDFSVAQCRELVETYRVPGVHFYTLNQSPASSDIVRRLKSS
>A0A0P6XFM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bellilinea caldifistulae|TrEMBL
MKDSRFLDLLQTSQRPLLSDGAMGTLLNQRGISFERCFDELNLTDPALVASIHREYIDAG
SQIIQTNTFGANRFKLAHHGLENQVAEINAAAVELARRVVMASFKDVLIAGDVGPLGVRL
APFGRVQPEQARQVFAEQIAALIEAGVDLLIIETMTDLYEVREAIAAARQINPDIPVVAS
MTFTRDDRTLLGDDPIKVARGIQQAGADVIGINCSGGPNQILRILKQMHLALPQARFSVM
PNAGWPEQVGGRIMYPASPEYFGEYALAFWQAGASLIGGCCGTTPGHISVMRQAIETRPL
EKFSNGFSLAVVEKEEVSQERQAPTLMAQKLMDGRFLIAVEMDPPRGLTTQKLLAGSSLL
AEAGADVINVADSPMARMRMSPWAVCRLIQEKVGIETVLHFPTRGRNLLRVQGDLLAAHA
LGVRNVFVVMGDPTAIGDYPDAMDNYDLVPSGLIKLIKQGFNAGVDHAGVDIGQPTSFFV
GCALNLTPSNPESELKNLRRKLNAGADFILTQPIYDLKPALQFLERIKLEIEDFHTPLLV
GVLPLVSARHAAFLQHEVPGVNIPQEIHDRMVSAGERAAQTGIEIAFELISQMVEFAQGI
YLMPAFNRFDYAAEIIERVRQLELPAEQQKFPPA
>A0A8H7ZK66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida metapsilosis|TrEMBL
MKITDKLNQAHVGISNPPPATFSFEFFVPKTAQGVQNLYDRMDRMYDLNPIFIDITWNAG
GRSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALDKAYKSGCQNILALRGDPPL
DGSESTGDFKYAKDLVRYIRKKYGNHFNIGVAAYPEGQPEEEDETKTLHYLKEKCDEGAD
FIITQMFYDVDNFISWCGKLRKIGIEIPIIPGIMPISTYAAFIRRANWSQIKIPQHFLDA
LDPIKDDDYLVREKGTELVSDMCNKLIQSGYVNHLHFYTMNLEKSTIMALEKLNLIEAIK
SHEVVGGTELPWRKSLHPERSKESIRPIFWQNRKYSYISRTATWDEFPNGRWGDSRSPAF
GDIDLCASELLRQSPKRALELWGVPQNLKQLSNLVVSYLSGDLKSLPWSDGAVGEDTKVI
IDDLVNLNKRGLLTMNSQPALNSVKSSEKVFGWGPKNGYVYQKQYLEFICHRDVIDKLLA
RIQEFNKTQGDSSSSIISYYAVDLSGKLQTNCKPDDINAVTWGVFPGEEILQPTIVEQTS
FLAWKDEVYRLFSEWNKVLSSNLVDIDDDSKLQNFKTLMNQVEHDFVLCNLVNNDFIDSN
STLFNLIYDLNLPELS
>A0A7V5ABB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Acetothermia bacterium|TrEMBL
MKFRERLAQGEFVITCEAAPPKGTDTKEALENVRRLAPLVHAFNVTDLQSSVVRMSSWAL
CALIRREGFEPILQVTCRDRNRLALQADLLGAWALGIENVLALTGDYPTLGDHPQAKPVF
DLDSVQLIALIQALNSGKDLVGNELSGKTDFFVGAVINPAADPLEPHLLRLRLKVELGAR
FVQTQAVFDPEAFVRFAQKAEPLGIPILAGIIPLKSAKMARFMNENIAGIRVPEELIREM
EAAKTAEDRKKRSVEICVRIIREVRPYCQGIHIMPMGWEELVPEILELAGLP
>A0A6A2Z044|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hibiscus syriacus|TrEMBL
MLKMKVIEKIQSSPQDQGKVVFSFEFFPPKIEDGVENLFERMDRMVAHNLSFCDITWGTG
GSTVDLTLYIANKVQNIICVETMMHLTCTNMSVEKLDHALEIIKSNGIQNVIALRGDPPH
GQDKFVHVEGSFACALDLVKHIRAKYGDYSGIAVAGYPEAHLDAIGDNGVATPEAYQNDL
AYLKRKVDAGTDLIVTQLFYDEITAALEPIKDNDEAVKAYGIHLGTEMCRKILANGIKTL
HLYTLNMEQDHILKANGMDQGKVVFSFEFFPPKTEDGVENLFERMDQIVAHNLSFCDITW
GTGGSTVDLTLYIANKVQNIISVETIMHLTCTNMSVEKLDHALEIIKSNVIQNVIAIRGD
PPHGQDKFVHVEGGFACALDLVKHIRAKYGDYSGITVAGYPEAHLDAIGDNGVATPEAYQ
NDLAYLKRKVDAGADLIFTQLFYDEITAALEPIKDNDEAVKAYGIHLGTEMCRKILANGI
KTLHLYTLNMEQNHILKANGMVNC
>A0A1W9WN88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_89|TrEMBL
MLRIFSDEILNPKNFVVTLELVPGRESGGRSVDTLKGIARDAFADGRISAVSITDNPGGN
PSLSPDVLGYEIFKCGLDVIIHFACRDLNRVGMESRALQLASMGMKNILALTGDYSGKGF
GGQGKPVFDFDSVILTTMFKSLNQKLLKSGDPDGFFSGCAVSPFKTTEAETHAQYGKLDK
KLGAGASFVVTQLGYDVEKFRELISVLFQKGMKPPVMGSVYLLSPRSARAMNRGRVPGAY
VPDALFKQVIKEWGIIRSGLKIAIDRAARLGVILKGLGYRGIHIGGIHKSFKTVEAILDR
MDEIEDSWEDFLDEFNLGRTKSCYYLFNSPVSEKKLPVPAMIKEKITEHYPHAVLRTAHN
LFFDKKAGFAPFYRKLADMLEKNNKAWLLKLILEDPLKKTMLSCQSCGDCAIQHLAFQCP
ESGCPKHTRNGACGGSRDGWCEVNPDRKCVWVRAYTRLKHCGLALTLGRDFVPPRMWELN
KTSSWINFHLEKDHQKENSQAFQVKTIPPV
>L0WA20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax hongdengensis A-11-3|TrEMBL
MKRISFEFFPPKTDQGKEKLLATQQKLLVKKPEFFSCTFGAGGSTRDNTRDMVGKLREQH
ADTAPHLSCIGQSREEIMELVNGYKAAGVTRIVALRGDLPSGMGYAQSELKYADELVALI
REETGDHFTLEVAAYPEMHPQARSFEDDIAHFKRKVDAGANSGLTQYFYNADAYGYYLDA
LQKIGCQAPVYPGIMPILNVANLLRFSDNCGADVPRWLRSKLNDIKDDEAAVKAYGEEVV
TRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGL
>A0A0Q8QR93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Root720|TrEMBL
MTSVSLSQLEEARRALDTPLFADLAGDAAVSFEFFPPKTEKMEETLWSAIQTLAPLAPRF
VSVTYGAGGSTRERTHHTVARIARETPIPAAAHLTCVEASKGEIEEIAREYWAAGVRHIV
ALRGDPPTEGAAFTPHPDGYRNAADLVAGLKAIHPFEISVAAYPECHPEAASMESDLANL
KAKFDAGATRAITQFFFSPEAYFRFRDKAHAAGVEGEIVPGILPVSNVAQTRKFAGLCGA
AIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVRQFHFYTLNRAELSFAICHL
LGLRAKAGRLENAA
>A0A418Y0E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax profundi|TrEMBL
MKRISFEFFPPKTDAGKEKLLATQKKLLAKNPDFFSCTFGAGGSTRDNTRDMVNKLRAQH
GDTAPHLSCIGQSRDEILELVNGYKEAGVTRIVALRGDLPSGMGYAQSEIKYADELVALI
RQETGDHFQLEVAAYPEMHPEARSFADDIDHFKRKIDAGANSGLTQYFYNADAYGYYLDA
LQKIGCDAPVYPGIMPILNVANLLRFSANCGADVPRWLSCKLNDLKDDDAAVKAYGEEVV
TRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGL
>A0A658A5J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
CVGATRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANELVSFIREETGDWF
HIEVAAYPEMHPQAANPSADLNHFVNKVKAGADAAITQYFFNADAYFDFVDRAQAKGVNV
PIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAFGVDVVTELCQTLL
DNGAPGLHFYTLNHAEAPLAVWKELAVQA
>A0A4R8KTC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. 75|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRIKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVSRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A1W9WYT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_89|TrEMBL
MKTESRLEKVLTSGALAVTSEVGPPRGVDPEIVKTKANMIKDHVDGINVTDNQTAMVRMS
SMAAGVIIKQMGLDPIIQMVTRDRNRLAMQSEIIGASAFGIDTMLCLSGDHPKFGDHPMA
KSVYDIDSIQLIQTVKDMRDEGKFQGGADMKGRPNMYIGAAANPFADPFELRVMRLAKKA
KAGVDFVQTQCIFNLDKFELWMKGVEDRELDKEVHVLAGITPMKSVGMARYMKNKVPGMD
IPDEVIKRLAGVSKEQQPEEGIKIAVESIERLKETKGVHGFHIMAIEWEERVPEIVEQAG
LYPRPQF
>A0A3D0DVS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp|TrEMBL
METHNFSIEFFPPKTPEGAEKLRATRRQLAELSPTYFSVTFGAGGSTQQGTLDTVLDIMA
DGHPAAPHLSCIGATRESIRALLKQFQQHGIRRLVALRGDLPSGYGGAGELRYANELVEF
IRQETGDWFHIEVAAYPEMHPQARSPQDDLQNFARKVHAGANAAITQYFYNADAYFQFVD
NVRKMGIEVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VSSLCERLLAGGAPGLHFYSMNQAVATTAIWKRLTGK
>S0G1B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotignum phosphitoxidans DSM 13687|TrEMBL
MKTDSRLEKVLASGELAVTSECGPPRGCRPEKVTEKAALLKDHVDGINVTDNQTAMVRMS
SCTAGILIKQMGLDPIIQMVSRDRNRLAMQSEILGAYSFGINTMLCLSGDHAKFGDHPMA
QGVFDIDSVQMIKMVQQMRDKGLFQGGAKIDGPPKMFIGAAANPFADPFELRVMRLAKKI
KAGVDFIQTQCIFNLDKFEEWMKGVVERGLDEQVHILAGITPMKSVGMARYMKNKVPGMD
IPDDVIKRLEGVPKEQQPEEGIKMAVEAIERLKQVKGVHGFHIMAIEWEEKVPQIVEKAG
LYPRPKV
>A0A5B2W4E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga agrisoli|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPAFINVTYHRSEHMFKKR
ADGSFEKVEIRKRPGTVGICAAIMNHYNVDAVPHLICGGFSREETENALIDLNFLGVDNV
LVLRGDAPKNETFFEPDPHGHRYAIELLQQVVNMNNGIYQEEDLQGGLKTKFCIGVAGYP
EKHFESPNMQTDISHLKRKVEQGADYIVTQMFFNNQKFFDFVAKCREMGITVPIIPGLKP
LTSKKQLTVLPRTFFVDIPDELASEVMKCKTDKEVEEVGTRWLIQQSRELKQFGVPVLHY
YTLGKPNVIKTVVEAII
>A0A7X5X1W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces malaysiensis|TrEMBL
MRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSVTYGAGGSSREGTVRV
TERIATDTTLTPVAHLTAVNHSRAELRNIIGQYAGAGIRNMLALRGDPPGDPMGEWISHP
DGLDYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIGHFIDKCRAGADFAITQMFF
YPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIDYATELCARLMAEEIPGLHFITLNHSPATLEIYENLGLHQRS
>A0A6I3C700|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MLDVTKIRDLLAAGPTISFEFFPPKTDTAMRALDAALEELSLVEPSFVSVTYGAGGSTKD
RTRSIVLGINETRPFPAMPHLTCMSHTKAEVIDLLDDYADHGIENVLALAGDPPTDADTP
LGEFRYALELVELVRDKGDFSVGVAAFPELHPRSQGRSADDRQHLAAKLEVADFAITQFF
ADADDYGRLLDDLDALGVTKPVLPGIMAPNNPAGYRRMAAMNGTRVPEALLARIDAADAA
DAISLAVEATTQQCLRLRELGAPGLHFYTLNRSELTRRVHANLVG
>A0A5N6HCL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus flavus|TrEMBL
MGMFPFPLIGGPVKLRPKPFPPRWISPQSSLFNYHLSRNFAGTDSGIKMEKITDKIAALP
PDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGSTAQRSLELAEICQ
RQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNRD
FTFAVDLVRYIRQKHGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTQAGADFIM
TQLTYDIEAYTRFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVQIPPQILS
KLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLRGFHFYTLNLEKTVSFILERCDLIP
PYSEDFDAIEEGGDISAMDGAHLRSLTRRRASSINSLPHNRVIVDKLHASEVSSKASVSH
EAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPS
LHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPE
LLQLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKP
LLQKHGHEKLAWFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTI
IEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNDIKDDVWLVCVVGQDFGAGTEMGSE
EEEDEKKFMWRVLLNAKK
>A0A2N1IV08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas monteilii|TrEMBL
MSLLKTALREKNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFFTLQLGF
DAAKHQEAIHWMHRQASPKPMLACLMSLTHGRATMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALEARIEHWQTQLQSLEQWTPA
WHASWQMPGLPAVTFHPPQAGWRLGESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPLWATRAGAQVLHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A3M7KAF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus flavus|TrEMBL
MGMFPFPLIGGPVKLRPKPFPPRWISPQSSLFNYHLSRNFAGTDSGIKMEKITDKIAALP
PDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGSTAQRSLELAEICQ
RQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNRD
FTFAVDLVRYIRQKHGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTQAGADFIM
TQLTYDIEAYTRFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVQIPPQILA
KLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLRGFHFYTLNLEKTVSFILERCDLIP
PYSEDFDAIEEGGDISAMDGAHLRSLTRRRASSINSLPHNRVIVDKLHASEVSSKASVSH
EAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPS
LHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPE
LLQLIDGNGWWTLASQPAVNGVRSDDPVYGWGPPREGFVFQKPFVEFFCPSKDYHSILKP
LLQKHGHEKLAWFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTI
IEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNDIKDDVWLVCVVGQDFGAGTEMGSE
EEEDEKKFMWRVLLNAKK
>A0A7W0UK87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
GVPVLAYKTFVEDGETLAEGLPERAAREISAWGADLVGANCTVGPQRMVGIVEGMSTAAG
PVAAFPNPGLPQLVQGRIRYSRDVEHFAHYGVELARAGARLIGGCCGTTPAHVRALSEAL
RDFRSDDAARKRVAVAKKEDRKQTSSEPVSGFAEKLRTGFAVTVEVDLPRGNDITAVVEA
AKRLKERGVDAVDISDGARARLRMHPMAAARIVQDEAGIEVVAHLSCRDRNIIGLQADLL
GAAALGVRNILAVTGDPAQIGDYPEATSVFDTDSVGLVHTLSRMNAGEDLSGNPIGTPPG
FLIGASFNPTAEDLDSEIDKLQRKIEAGAHAFWTQPVFEIGALERALEKTKDMAPSILLG
LMPLRSPRQAEFLHHEVPGINIPKDVRDKLATLSPEDAPKYGVEVARNLLVKAKPLVNGA
YVMPPASAPDLAGDVIESVDG
>A0A538BQP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MANRFLERLGSGPPIVADGGMGALVSSAVPRLRCPEEANLRAPDAVVSLHVGFINAGAEL
IETNTFGANRRKLATYFLEDEFERINSTAVKLARDAREVTGREVFVAGSIGPLGEVIETF
YDLDELVDAIEAVKSVSSLPIVALLTFDEGAETLSGVTARDAAERLAELDVAAIGANHGA
GLLAALAALEQFQTDGLPLAALPNIGLASLSGGRVIFPHATPDYFAEFAAHARDLGARVI
GGCCGTTPTEIAAIRTALEEEREPRAALHFEERELVVSLGEEQGETRLAQALREGKWVVS
AQLDPPLGSNVGGLIEISRALEESGEVGFVDLNDNAGARAGMSALMASAAIERACGIETI
PHLTTRDTTVMGLESMLFGAQAEGIRNVLAVTGDPPEVGDYPGSKGIYEIDSIGLTQLMA
SLNRGEDVNGRPIDAPTSFYIGVAVNPSADDLDFELDRFEQKIEAGAKFAMTQLVFDLEY
LDRFLDRLGGSAPLPLLLGVCPLWSYRLALRFHNELPGIIVPEPLQDALRDAGADAADVG
MEHAKRLLREARDRVAGVYLVVPYRQPLRVLELLA
>A0A7W0QJ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDRFSKRLSSGPPIVADGGMGSLVTSAVARLRCPEEANLRAPESVLSLHLGFIRAGAELI
ETNTFGANRHKLRTQYLEDEVKAINEAAVKIARDAREVSGRDVFIAGAIGPLGEIGARRD
DRAALFTEQAELLEGRGVDLFLVETFYELDELETAIGAVRSVSSLPIVALLTFDEDAHTL
GGVSAARAASALDDQDVAAIGANHGLGLQAALRALEQMSGSGKPLAALPNVGLASLAGQR
VIFPHTTPEYFADFAAHAQELGARIIGGCCGTTPTQIAAIRDAVDAGRRSSVPMVVRERQ
VVVAVTEPERETLLQQKLRSGEFVVSVEIDPPRGGQAQAMLDLARTLKESGHVDVVDVND
NPRARARMSGLMASATIERVAEIETIPHLTPRDSSIAGLESMLLGAHAEGIRNVLAVTGD
PPEAGDYPGSGGVYEVDSIGLSRIITQMNAGEDFNGREIDAPTSFFLGVAVNPAADDLGQ
ELERFEQKLEAGAKFAMTQVLFDFAYLDAFFERLGRPCPIPLLIGIFYVKS
>A0A7V3LHS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTMGKYRDACNSGKFVISGEIGPPKGTNVERMLHHIDLLKDRVDGLNVTDNQSAVMRMGS
LVVSGEIVRRGGDAIFQTTCRDRNRLALQSDLLSAAFLGITNVLCLTGDHPIVGDHKEAK
GVFDFDSVHLIQCCRKMNEGYDWAGNQLDGPTDFFIGAVVTPESDPLEPQLYKFARKVEA
GVDFIQTQAVYDMDHIHRFMEKDREITAGTNVKIMTGLVVLTSLGMAK
>A0A3D9KZ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinoscillum furvescens DSM 4134|TrEMBL
MKVTEHIANADGKTLFSLEIIPPKKGDSIESLFGHIDPLMEFKPPFIDVTYHREEFVYKN
RGNGLLEKKTIRKRPGTVGICAAIKNRYEVDPVPHIICGGFTKEETENALIDLNFLGIDN
VLVLRGDSIAEEKTFKPEPDGNAYAIDLVNQVVSMNNARYLDEELQNAVPTSFCIGVAGY
PEKHFEAPNMKSDLKYLKEKIDRGAEYIVTQMFFDNQKYFDFVEQCRAACITVPIIPGLK
PITTKGHMTVLPSIFHIDIPDDLYVEIEKCKTNKEVKEVGIAWGIQQSKELMDAGVPVLH
YYSMGKSDSVYRIAKELF
>A0A7J4G2X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Geothermarchaeota archaeon|TrEMBL
LGAALIPYRDGEENIMLSKMESGADFFQTQITLDYKPLINLLENIADKVSGDISILVGVI
PYKVGIENIISKIIGMRSRDILMLDIERYINHLEDMLKKILDLSNVLGFVNIGIHIYPIR
WVYESLEYTVKLISRL
>A0A7K0TDG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVVRTSYSLEFFPPKDGEGEARLWDALESLKRINPTFVSVTYGAGGSTRNRTIGVTEEVT
HRTNFPTVAHLTCVGSSRQELISILHMYKAAGIKGILALRGDPVGGPRAPWTPTSDGFTH
ADELVQLIHEFGEFDIGVAAFPDGHPGSDGDSKKDIDVLLRKEFLGAQFATTQFFFEVSK
YEQLVDGLQARGSSLPIIPGILPITNVKQLQRMAELGGTPIPSDVAKSFGAVENDPIAVH
QLGIELASQLCEDLLTAGAPSLHFYTMNNATATLEIYGNLNSAN
>A0A7W0R326|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MLSEVRNFGTGALFEGYPDFKIGTVAKVGKPLGWRAAADFLFVQITYAPHRLVEWRRSLD
YNGGVYVGVLVLASARMARRVNATIPDIRVPERIIDKLESDPAYGLDFALEQIETIRDSG
AFDGVHLVPVTRFRQVAEKLQSLGAK
>A0A7K1BDF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSVMREKLENSNETVFTAEFPSIDGGGMAKVEKSAARLAPWFDAVNATDNPAAHAHASNT
SSAIAMKMHGIEPIMQIVCRDKNRLAIQADMMGAALHGIENISLLTGDDVTAGDEPETRR
VFDIDSTQAINIARILTTGQYLSGRKINPAPDFYISAVENPAAPPFDYRIERALKKYRAG
AKYLQLQICYHPDRLEKFCAGVAKIAPDLKLIPTIVLVKSAKPMSFMNDKVPGIDIPLDS
INRVASATDQADEAYKLTLELAKHALSLPAVRGLHVTDFRHDDSLDSFMYDLGQKPRN
>A0A6I2XAP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTRIADLLRAGRTLSFEFFPPKTDEAALALRTTIAELDELHPSFVSVTYGAGGSTRERTR
DVVIAIEREVGLAAMAHLTCVAHTRSQLDSLLDEYHAAGVENILALAGDPVLDDDGRPID
GEFEYSLELVELIAEREQFSIGVAAHPEGHPRSVDLATDRRHLATKLEIADFAITQFFFE
AEPYLRMVDELAALGCTKPVLPGIMPVTNVGQVTRFAQLAGAAFPAHLADRFESLADDPA
GVRALGVELATELCQRLLDEGVPGLHFYTLNRSTATRDIARELDLTQ
>A0A7W2L7W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas monteilii|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVAPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7K0PZ75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAVVSRPDAGLPRAGRAQLAAALRDATYEVLPFKSAEDKVLADVPTDVALTVTTTEAKGL
GPTVDLAVRLTAAGYRAAPHLAARLVRDRAHLADLVAQLREAGVDRVFVIGGDAAEPAGD
FTDALGLLEALDEMGRPFSTVGIGGYPEGHGSIADEHIERALEAKAEHATQVITQLCFDA
ATTVRWARTAYERGVTLPVRVGIPGAISRQKLIRVSAGLGLGQSARFLKKQQNMFWRFFL
PGGYSPDKLIQQLTPAFGVPGSGLEGLHVFTFNELDTTEAWRQRWLARLP
>A0A7V9EL84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPLQEPAAPLENAPDRAIGARPHLLARPTIEIFPVEGIAARVARTRPASIAITCSPRRGI
GATLDLAERLIDAGIDVTPHLSARLVVDRAHAQRIGARLARLGIGHIFVIGGDVKQPAGP
FPSAASLLNFFAEGGFTFDQVGVASYPEGHPTVDDATLWHELRLKQRWATYAVTQLCFEA
GAIAAWIRNARAHDVTLPVHVGIAGVVERARLIRLALRIGVGDSSRFVSKNRNLMAGLLG
RRAYSPGPLIAELSRRTGADDIAGYHFYTFNQVEATEEWRRRALEAAP
>A0A7K0S2E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRIDELLKGSSEPQFSFEFFPPKSEEGDRNLLEAISQL
>Q9WYA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)|TrEMBL
MRKSLEIGKCVVLEVLTPRGTNLGRFMEFTEEAWKTGIDAFTVTDMPMGRVRMAPWAASH
LLVESGKDVLMHFTRNTRNMIRIQSDLLGCHALGVKNLLLLSGDNPSHGDYPETTSVNDI
DILDLIRLTKLMNEGTDLAGNKIYGKTDFFVGGALNPFSDKDIKRAKQKIEAGVDFLVTQ
PLFNSEVAKKIKEELNTKILASIVFFENAKQMSYFSSVPGIEIPDEIVNSTEKGDDYLKE
KSFESVLRFVEETKGVLDGFYIVAIVKDLEKIRKVVEIAKS
>Q7BK23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium chloromethanicum|TrEMBL
MTRLTTSLAGTQPNEDGSSLASEKPLMGNISIELLPEHVATFHPTAANLKPGSFVFLTHI
GGKSLAAQAGAAARIKAMGYEPVCHLGARNFTSRDEYANHLSALSDAGVTTVLMIGGNSS
DSVPPMHSAMELLSHSIVPRTGVKRIFFAGHPEGHPSIPPEILVPTLLEKINVARELSLV
PEIVTQFAFDGAAMAAWGAGLRKAGIDVPIRFGVAGVTSLPKLIKFAMLCGVGASLKGLS
RQGGSILKAMRDQDPGDVISQLRIGTEA
>G2Q8K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myceliophthora thermophila (strain ATCC 42464 / BCRC 31852 / DSM 1799)|TrEMBL
MGEFLPSLELPPEAVKNHAMEKITDKIAALPAGQHYFSLEFFPPKTAMGFSNLRGRLDRM
ARALRPLFVNVTWGAGGSTAVKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALDDAK
ALGIRNILALRGDPPRRAEYLDVSEPEPDEEEEFSWAVDLVRYIRKMHGDYFCIGVAAYP
EGHADESHPLGQSLEHDLPYLVEKTRAGADFIMTQLFFDIEAYKHFEKTLREHPSGAFKD
IPIIPGLMPIQSYQMIKRTTKLSHAKIPEPLMARLDAVRNDDEKVKEVGVDIVSELVEQI
KEIKSRTGGPRGFHFYTLNLEKAVSFIVERTGLIAPLTPEEAEGAAVDRNPLPDVRFLRI
NGLTPEQSSHDHPHLRRKPSVGSDPRDRVIVQERSASHPDWEATPLEASVPAEPINSRAN
TLAISEGEGVLGREATWDDFPNGRWGDARSPAYGQIDGYGVSLHVTVAQARQLWGAPATP
RDVSDIFIRHLRGELPTIPWSEESFSPETDKIRDRLVALNSKGWWTLASQPAVNGLRSSD
PVFGWGPQNGFVFQKAFVEFFLPSKDWEVLEQKLKRPEMKNAVCFYATNARGDFVSSDTV
LPPPPPPTAAAPAEQREASTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWREWAK
IYPRGSDSERFLEAVRADTWLVNIIHHDYVDPDALWDFLLG
>A0A538JDS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSRLEDRIRAGGFVLTAELLTVNTGGLDAVHERFEPYEDYVDAINATDNTAAHAHAAPLA
VAIALKQLGMEPVMQLVCRDRNRLALEADIVGAALHGIENICCLTGDDVTAGDEPEARRV
FDLDSPQLIATAQAISGGRYLSGRRIEPAPHLFIGAVENPGAPPYEARVERALKKVRAGA
RFFQLQLCFDKERVERFMRAAVESGLAAQAAIIQSICLVRSPSALRFVDEKVPGITVPHE
LIEHCERADDPEEACFQLGAEFAAHALAQPGVRGLHLISFRREAGIARLCRQLGIPTREE
RETSGYRHPVAV
>A0A3A6KDI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AF35-22|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A4V1GCH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachnia propionica|TrEMBL
MSPTVAELLRDAASPTLSFEFFPPRTPEEQPRFEATVAKLGRFHPAFLSVTYGASGSTRD
RTVAATAALGSAQHATVVGHLTCVSQSTDDLLRTLDAFADAGVSDILAIRGDMPGGPQQP
WERHPDGLGNATELVRLIKAHGDFCVGVAAFPNVHQPDNDPELDARIVAEKAAAGADYAI
TQLFFESHRYVELVNRVRERGSQIPIIPGIAPLTVITQIERFASLADCPLPKDFVAALRA
ARNPAEVRSIGLSRAVNLCRELLAAGAPGLQFFTQNRWKATSEVLDAIGWGDRVS
>A0A427F9V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. o96-267|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTVNTVLQLD
GDVKVPTAPHLSCVGDSKAELRELLNLYQSAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGEHFHIEIAAYPEMHPQARNLEDDIANFVRKAKAGANSAITQYFFNADCYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIDSIQAFG
EQVISEMCERLLAGGAPGLHFYTLNQADPSLAIWNNLKLPR
>N8VJK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 102159|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLHIVHQELQRLNPEFFSITYGAGGSTRERTLATIHDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGNHFHIEVAAYPEMHPQADSFDADIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERLEKEGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A239EMN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus pulveris|TrEMBL
MTPTVRELLAGGRPTWSFEFFPPKSPEGAGQLWTALRELERLHPSFVSVTYGAGGSTREG
TVSVTERIATETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQAE
WVAHPEGLQYAAQLVELIRSMGDFCVGVAAFPERHPRSPDFDTDVEMFVRKCRAGADFAI
TQMFFRPEDYLRLRDRVAATGCGVPIIAGVMPVTSARQISRIVQLSGQAFPEQLAARFAE
LDGDTPEARAAVRALGVEVATELCRTLLDEGVPGIHFITMNRSTATREVHANLAAVGSPH
>A0A538FZE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPDRFEKRLEHGPPVVTDGGMGVLVSSAVPGLRCPEEANIRAPESVVSLHASFINAGAEL
IETNTFGANRHKLRSQFLADEVEAINETGVKLAREAREISGRDVYVAGSIGPLGELGGLA
ADERGPVFAEQASLLEGRGVDLFMVETFFDLDELTAAIEAVQGVSSLPIVAMLTFDEDAE
TFGGVSARDAVDRLSAYELAAVGANHGAGLHAALAALEAMGDGRPLAALPNVGLASLSGG
RVIYPHATPEYFAEFAAQARALGARVIGGCCGTTPTEIAAIARAVEEERKPTAPFAAAER
ELVVAAHERPEETELAQKLRAGEWITCVELDPPKGGTYESMLAVTKTLKDSGEVGFVDIN
DNPMARARANALMAAIAIERTCAIETIPHVTPRDTSVMGLQSQLLAAHAEGVRNVLAVTG
DPPHVGDYPGSRGVYEVDSIGLAKVVTRLNAGEDFNGKAIDAPTSFFLGVAVNPSADDLE
TELDRFRQKVEAGAQFAMTQALFDVAYLDRFEELVGGWPIPILVGIFMVRSHQLAVRLHN
EVPGIVVPEDVQNRLRDAGPRAAEEGLALARELYEQAREKAAGVYVIPPFKQPEAALELL
GIE
>A0A3S5ESX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium segmentosum|TrEMBL
MSPRFSASAPLDSMSEEELMVPERLALSFEVIPPRHDADEAKIDRLLETLESYHPDYIAV
TSSKRSGWLEGTTAFIERISRTTSMRPLAHLACTAGSRTELIGWINRLVDAGVRGLLALR
GDLPEEGLPEHYPQHADELISLIRQLERQQAARFAAGRLAVGVACYPSGHVESKNEDEDF
DVLLKKQRLGADFAITQLFFDAQDYLRFTKKAQLAGVHIPLIPGIMPMTSLRRVERMGEL
SGLAVPERVRSALAAATTPEEEYETGMELTTELARDIVAGGASGLHIYTHNNPDNTHDLL
TRIGVDNDQR
>A0A3S4ZKS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachnia propionica|TrEMBL
MSPTVAELLRDAASPTLSFEFFPPRTPEEQPRFEATVAKLGRFHPAFLSVTYGASGSTRD
RTVAATAALGAAQHATVVGHLTCVSQSTDDLLRTLDAFVDAGVRDILAIRGDMPGGPQQP
WEKHPDGLGNATELVRLIKAHGDFCVGVAAFPNVHQPDNDPELDARIVAEKAAAGADYAI
TQLFFESHRYVELVNRVRERGSQIPIIPGIAPLTVITQIERFASLADCPLPEDFVAALRA
ARNPAEVRSIGLSRAVNLCRELLAAGAPGLQFFTQNRWKATSEVLDAIGWGDRVS
>G2Q3E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myceliophthora thermophila (strain ATCC 42464 / BCRC 31852 / DSM 1799)|TrEMBL
MHIREMLAEAERTGNPSFSFEYFPPKTAQGVQNLYDRMERMYNFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYLGLEACMHLTCTDMGEEKVNDALRKAYKAGCTNILALRGDPPRDKEK
WEATDTKFRYARDLVAHIRKMYGNHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDMGASF
IVTQMFYDVDNFLRWVGKVRERGITVPIVPGIMPIATYASFLRRANHMNCKIPEEWMAKL
EPVKNDDVAVRDIGKVLVADMCRKILAAGIRHLHFYTMNLAQATRMVLEELDWLPSPERP
LKQALPWKQSLGLGRRTEDVRPIFWRNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNRQKWGEPTCVRDIANLFVRYLNKEIDYLPWSEAPVAEEAELIKKELID
LNKRGLITVNSQPAVNGAKSNHPVHGWGPSNGYVYQKAYLEMLVAPELFPEVKRRIEQHP
DLTYHAVTKAGNLYTNAQFEGPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFQLGTEW
ARCYESGSPSRLILEEIMNTWYLVNIVNNDFHRGETIFEVLDGLEVPNLDRVPEPQGNGV
TNGAPNGVEAST
>A0A1V5TII4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium ADurb.Bin266|TrEMBL
MKVIEHLNNATNPLISFELIPPKRGGDIRGLLSVIDDIAKYNPPYIDITSHAAEVFYEET
PTGIKKKVKRKRPGTLGICALIQNKYNIDAVPHVLSKGFTREETEDFLIELNYLQIQNVL
AIRGDDSGYEKPIPEGKSKNPHAVDLVKQIINMNNGKYLEDSLLDAKPTDFCIGVGGYPE
KHFEAPNLKTDIKYVKEKVDAGAEYIVTQMFYDNKYYFNYVDMCREIGIDVPIIPGLKVL
TSRAHLTSVPKNFFLNIPDELSDEVMAAKPEHVLDIGVEWAVKQVEELLNRNVKSIHFYV
MQNSKPIIKLMERLKL
>A0A1B9RSZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. AC27/96|TrEMBL
MSSKSENSQSGIRISFEFFPPKSEEAEQQLWNTVADLSDWEPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLATGVRRFVALRGDPPGGVGSAYQP
HPGGYANAADLVAALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRAAGIAIPVVPGIMPIQNLTQLKRFAGACGTSIPLALDQRFEGLEE
NTDERASVAADVAAEQIQDLMRRGIHEFHLYTMNRSPLVSAVLERLGLQRRVDARAGAAA
>A0A7V4JQY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacterium geofontis|TrEMBL
MEVKTNLQKVLESGEFAVTAEIEPPKNADPELIKEKAKWFKGYVDAINITDNPRATVKMS
SLAGAVILIREGIEPIMHITCRDRNRIAIQSDLLGAYALGIKNVLCLTGDHISLGDHPQA
KPVFDLDSIHLLSLVKALNEGKFFNGDEIKGGRPYFFIGAVENPFADPLEFRPIRLAKKI
KAGAKFVQTQIVYNLERFRKFLNLCEELGILEKVYILAGIMPPKSSKMLKLIKENKVPGI
EVPDKLIKRMESAKDEKEEGINIAIEIIEKVKEMPGINGVHIMAVGWEFIIPEIIKRAKL
YPRPAL
>A0A7Z1WV11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSQVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEHAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVT
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKDKLIPTVPLETRGTSSWKNWYLATEA
>A0A8C7MZS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus kisutch|TrEMBL
CSFYECLGFGGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTESGDHWFSLEFFP
PRTASGAVNLVSRSVAETHLFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY
CGLESILHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEADSYDEDLRHLKEKVDAGADFIITQLFFRADTFLKF
VRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIRNYGI
EQTVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLK
MWGEELTSEQSVYKVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNLMMDELDKVNRRGV
LTINSQPTINGKPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPRVNYH
IVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPDEQPTDPAK
>A0A241ZCN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFEHFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQVGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEITRFSCQPTSKQLIKYRQLHVMHEALFGSKIVKGVGRFIFKASFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILREKLIPTVPLETRGTSSWKNWYLATEA
>A0A7Y4JSB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus exercitus|TrEMBL
MKIRNCLNPSRPSFSFEFFPPKTDAGVASLLRTVEELAPLEPGFVSVTYGAGGSTRDRTV
ELVTHIKQQSGIEAMAHLTCVGHTRDELRDVLRRLDAAGIENVLLLRGDPPQGQTTFEPV
PGGFRYAEELVRFVREEDFNFCIGGACYPEGHVETASREDDLQHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRVGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVGALKGRS
>A0A140L9M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidicola ferrireducens|TrEMBL
MENRFKESLLDKNVFSVTWELVPGRGAREKSIEEALEAAEAAAKGGKIHALTLTDNPGGN
PAMLPDYLAVEVLKKGIEPLVHFTCKDRNRSQIESQLYALDRAGVRNLLVMTGDYPVSGY
AGRPRPVFDLDPIHVLDLISQMNRGLEYKGIKGTVKHQPSDFFAGAVVSPFKATEAEQMV
QYFKLKKKVKAGAQFIVTQLGYDARKFHEVILFIRQQGWDIPVVGNIYVLPLATARIMNK
NKIPGCVVTDKLLAKLEEEAQSPDKGRQARLDRAAKMYAFMKGMGYDGVHIGGHNVKYED
VEYIIEKGEELSKNWMDFIHEFDFPIPGGFYYYEKDEKTGLNRPEPVNRKNRPLDAKVEF
VYPLSILTHKLMLEPGAPLWGLMRGIAKRVDGTSLERPYHAFEHLTKVCLYDCHDCGDCA
LMDLAYVCPMSQCPKNQRNGACGGSYMGWCEVYPNEKKCAYVRAYARLKHYGRENELDGD
IIPPPNWDLFQTSSWLNYYLGRDHSAKKLGIERVEKKKKDK
>A0A6J1WFQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Galleria mellonella|TrEMBL
MAKIIDIIKRNKQFSFSFEVTPDISEEEIDNLRVDPSFFSITWHAKTHQNKDLDIAPLKI
AKFLRSKEKEVLLHLSCDFMKRNFLFRVLLLLQEINIRNLFIILGEGFDPETSDFKDSSE
LIKCIRDHSGPYFCIGVAGLPDCNDDKLIALKRKINLGADFVLTQAFFEANIYKTFVHRC
KKIDINVPIIPGIFYFETYTQLSGFINMCQIKVSDNILEYVKNDQSNKITGGDIIKQLIR
DINDEKIYHVHFFTMNKLRVISDFVNKLY
>A0A8J6YVI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeovibrio sulfidiphilus|TrEMBL
MTTSFLPRIAPPESAPDVRVSFEFFPPKTDELNAQLWDCITALEPLAPDFVSVTYGAGGS
TRDRTHDIVARIASHTGLTPAAHLTCVGATREEVDEVARGYWDAGVRHIVALRGDPPDGV
SEYAPHPGGYAYAADLVAGLRKIADFEIFVAAYPEGHPAARSLDDDIDNLKRKLDAGATT
AISQFFFDVDHFRRFMDRVAAAGITAPVIPGILPVMSFATVQRFASVCGTAIPAWMPRLF
DGLDESVETRKMIAAALAFEQCRALQDDGHTRFHFYTLNRPDLTRAICHILGLRTAPAA
>A0A7G5ZQS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. Se63.02b|TrEMBL
MSSETETSGTPRVPFSFELYPPRSESSEEALHETVLRLAAAGPDFLSVTYGAGGSTGGRS
LDVLRFIRERTDVEPLAHLTCVGNTYAGAATLIREFLDAGILSFLALRGDPPVGQTEGVP
RRPRERGSTRAADRPRAGGAGSLRGVPGAGLPRAARVDPRRKVNIAVAAFPKGHPRATHR
TQDVEALLAKQAAGATFAITQLFFHPDDYLAFVERARAAGVSIPILPGIMPITSPARLKR
VLELTGEDLPSELAIALDVEPTAQGRREIGIEWAARLARDVVAGGAPGVHLYAFNQHETV
LTVLAEAGILPALRH
>A0A429H7Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GQGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A257N1G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium NSP1-1|TrEMBL
MQSQKKHPQLFSFEFYPPKTEEGVANLQIVHSKLAKLNPDFFSVTFGAGGSTRDLTFDTV
VAIQAKGIAAAPHLSCVASTKDNIRAILKDYQDNGIAKIVALRGDLPSGMMSAGEFRYAN
ELVEFIRQETGDYFQIHVAAYPEVHPQSASATEDFKNFKRKVEAGANAAITQYFYNAEAY
FYFRDSCEKNGIDIPVVPGIMPIT
>A0A0C1UPB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine actinobacterium MedAcidi-G3|TrEMBL
MSLFGSKEEDGAQRQVRWNLIDSARLEVIPLKNLDSQLQYLPEGSSVSVTASPAKTLEDT
WILSRKLSERGFKPVPHLAARMLTSETQLVSLISQLPEVGASELFLVGGDAPDPFGPFVD
SIQVLESILALDHGLDHIGVTAYPDGHSFINETTLSESLHAKQALLESAGLSGHASTQMC
FDPAAIRGWLQRERDAGLTIPIRLGIPGAVDRAKLLSIGARLGVGASLRFLKKNKSTVTR
LFAPGGYNPNKLLRPLTGVVEPLGIEGLHIFTFNQIEKTEMWRRANLS
>A0A3N5F7X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MTPSTVPVSFEFFPPNTPEGLTKLRETRRLLAQLEPEFFSVTFGAGGSTRDKSLGVVDEI
ATEGHAVAPHLSCVGATRDGIAELLEHWRGRGVRRLVALRGDLPSGMVDAGEFRYASDLV
AFVRERTGDWFRIEVAAYPEVHPQAASADADLEAFVHKVRAGADAAITQYFFNADAYFSF
VEAARARGVTVPIVPGIMPIMNYTQLARFSDACGAEIPRWIRMRLSGFGDDVESLRAFGH
DVVTALCARLLEGGAPGLHFYTLNQPGPSRAIWQALAR
>A0A0A0M8S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter defluvii IMMIB APB-9 = DSM 18482|TrEMBL
MVPISFEFYPPKTDSQRAQLDRAVGRLAEAAPEYVSVTFGAGGSTLSHTPEAIRRLKGEH
GLDAAPHITCMGGSREEIRGLLKLYRALGARRLVTLRGDLPSGMVTPGDLRHASELVEFI
RTETGDWFHIEVAAYPETHPQARDARADLRHFVDKVKAGADGAITQYFYNADAYFRFVED
IRAAGVDVPVVPGIMPISNYSQTRRFSEMCGAEIPRWVAQRMQAFGDDVESVRAFGAEVV
AQLCRRLMEGGAPGFHFYTLNLARPTLRVLEQLR
>A0A352BP28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVQLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAEI
>A0A2K9FAT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CMB-StM0423|TrEMBL
MATGIASTRNDRAVTVRELLASGKQSFSFEFAAPKTEKGERTLWNAVRRIEAVQPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVDHSVAELRNVIGQYADAGIRNMLAVR
GDPPGDPMGEWVAHPQGVSYAADLVRLIKESGDFCVGVAAFPERHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFHVDDYLRLRDRVAAAGCETPIIPEIMPVTNARQIQRFAELSGARF
PPELADRVLAVEDDRAAVRSIGIEYATDMCERLQSEGIPGLHFITLNHSTATLEIYQNLG
LHRPS
>A0A4Q7VZA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rivibacter subsaxonicus|TrEMBL
MSTSNSRLPLSLEFFPPKTPEGAEKLATVRRELYAVKPEFCSVTYGAGGSTQEGTWATVQ
AIRAEGVEAAPHFSCIGATQDAVRASLLQFKAAGIRRIVALRGDLPSGYGGFGEFRYASD
LVAFIRAETGEHFHIEVAAYPEAHPQARSPQADLKAFVAKVNAGASSAITQYFFNSDAYF
RFVDEAAAAGVRLDIVPGIMPITNSTQLIRFSEACGAEIPRWIRGRLEAFGDDRASIQAF
GLDVVTDLVDQLRTAGVPGIHFYAMNQSTAVLEICRRLGLA
>K6XPP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraglaciecola agarilytica NO2|TrEMBL
MVSYAQGIDALNQSLSEVKGINVSFEFFPPKTETMEKTLWKSVERLAPLKPKYMSVTYGA
NSGERDRTHEIVKRIQSETGIAAAPHLTCVDASREELKQIAKDYWASGIRKIVALRGDLP
EGYTEHVSYASDLVALLRDVADFDIAVAAYPEKHPEAPNSQFDLLNLKRKAEAGANQAIS
QFFFDAEVFLRFRDRAAAAGIDMDIVPGILPVTNYQTLQRFAGFTNVHVPNWLHKMYDGI
DKDDQTTRNLMGASIAMDMVKVLAKEGIRDFHFYTLNRCELSYAICHMLGVRAD
>A0A0Q9TQS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Soil787|TrEMBL
MTINLGHGSSMRPDNFLVTAELIPPRNWNPRPLVEQAVRYRGYVDAVDLSDNLLAIARLS
PVVGAFFVRQVGVEPIVQINLRDRNRMGIQSDLLGLAAIGVKNITILGGYPAKVGTEPNA
KEVYDLETMELVRYVRKMVDEGKLFDGTQMEEAPNFTIGTVENIAGKPIKELIDRLESKV
DNGTNFVRTQLVFDIDLIEEWMAEARRRGLHERATIMASVLPLRNADHVNTALKIPGIVI
PESFHARLAASESKDEGIAIAAELITQLRSIEGIKGIHIRPIGGAEDSVNNVVKAAGLMP
ITPLSIGALGA
>A0A154LBT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira lucentensis|TrEMBL
MTVKNDIAPQGTSHGDLRVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGST
RDRTHSSVTRIQGETGIPAAAHLTCVGHTKEEIEGIARNYWDEGIRSIVALRGDLPDAGD
KYVPTPGGYPYAVDLVEGLKRIADFDISVSAYPETHPDAPNTDFEIEYLKHKIDAGANRA
ITQFFFDNEVFLRFRDKCAAAGITAPIVPGILPVTNFGSLLKFADMCGASVPKRLHWRFE
DLDEDPDTRRMVAFHEAISQVEGLMAEGVTDFHFYTLNRAELTYAICHALGIRGVAQAAA
>A0A1M4Z5P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Seinonella peptonophila|TrEMBL
MEQSVREYMKEKVLLGDGAMATYLYQQGIPVQICYEELNLTEPSVIETVHRDYLRAGAKM
IETNTYGANRDRLKRYGLENKVVKMNREAVKIARQAAGKDAYVFGTIGSILAGRMMEYDP
EEYLDLYEEQATALLYGGVDGILLETFLDVHELKLAVQAVRGLTDLPLFAQFSLLDVGQT
RDAYPLSEAFLEVAEQVDGVGLNCRLGPVEILRCLEKTPIPAELQLSVFPNAGRLGIDDG
HYKYKSHPDYFAKTAELLIKQGVNLIGGCCGTTPEHISEMRRVVEQYRPVKRINPKPVKV
VEESPQPVIKLPKRSRPTVVEKVATQRTIICEFDTPRDLDVQDFLLGARRLHEAGIDAIT
MADNALATTRMSNLALGALLKTKWGIDPLLHVACRDRNLLGQQSHLMGLHALGIDQILVI
TGDPTRIGDLPGASSIYDVTSFELIRMVKQLNQGTSFSGKPLKQRAQFVVGTAFNPHVRK
IEKAVERLEKKIEMGADFVMTQPIYDTAGIQLLYEATQHLSVPIFVGIMPLTSYRNALFL
HNEVPGIKIADHVLAQMEQTTEPAAARRLGVEITKEVLDAAMETFLGIYLITPFSYWKMS
LDLTSYIREQDRKQNVAHDFK
>A0A1Q8V3E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalophilus pseudofirmus|TrEMBL
MDFLDALKERILIGDGAIGTLLYSKGITESCFEHLNITAEDKVYEVHEEYLQAGANVIQT
NTYAANSIKLANYGLEQKVTELNVKGVEIAKKAVRNLEAYVLATVGGISGLQTKNVTQEE
IMSSFDKQLDALLSANPDGLLFETFYSLDELKSVIKIARAKTDKPIVAQVALGDIGVLYG
GTPVSEALKTLIDTGANIVGLNCRMGPYHMIRSLEDVPLYDNAFLSCYPNASLPDYEDGR
FYYQSNPNYFGENALRFREQGVRLLGGCCGTTPEHIRAMAKALKEYPPITEKDIKKKQLV
IQVSKDRKDKEIPIDEIAKKRTAIIVELDPPKQLHVNKFLDGAKALHEAGVDAVTLADNS
LASPRVDNMALGALMHSQVGVRPLVHLTCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPT
KVGDFPGASSVYDLTSFDLISLIKQLNDGVSFSGKSLGQQANFTVGAAFNPNVRSLEKAV
IRMEKKITAGADYFMTQPVYSEQQIVDVYEATRHIKKPIYIGIMPLTSSRNAEFLHNEVP
GIKLTEDIRKRMAACGEDKARAEIEGLKIATSLIDKAIKYFNGIYLITPFLRYEMTVTLT
QYIHEQVKRTNSLQNQV
>A0A6L3ZWD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacterium sp|TrEMBL
MEHLNNAVNPLISFELIPPKRGGDIRGLLSVLDDISKFNPPFIDITSHAAEVFYEETPTG
IKKKVKRKRPGTLGICALIQNKYNIDAVPHVISKGFTREETEDFLIELNYLQIQNVLAIR
GDDSGYEKPIPEGKSKNPYAVDLVKQIINMNNGKYLEDSLLDALPTDFCIGVGGYPEKHF
EAPNLKTDIKYVKEKVDAGAEYIVTQMFYDNRHYFNYVDQCREIGIDVPIIPGLKVLTSK
AHLTSVPKNFFLNIPDELSDEIMAARPEQVLDIGVEWAAKQVEELLNANVKSIHFYVMQN
SKPILKLMERLKL
>A0A828SRI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 6014059|TrEMBL
MFRCLQGFDMTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRER
TLAAIEDFNGKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGE
LPYAQDLVRFIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFF
NPDSYFYFIERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDS
ESIKAFGHEVVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A4S4LIK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phellinidium pouzarii|TrEMBL
MSTYQSTSSSRLAPSASANNSGNLTNTTTASSSRSGALVPTNSVTTKDGAIVRARIDPTL
AVDDVIRQLCLNLKIQEPPVLYALRDDADELVTDDNLRKKIKGKVNLKLVSAPIIEAAEI
VEKLSMRDDKTLRMTXFFSAKVHSKQFANEFLQRDGLKELIDVIGVSHGNTLAYALNAMQ
NLMELDYGWSTLDHSFIRAVAQILSSSSSLINVCRPATAILKKLVEADPRSQPGPIVSSS
SRTPPAAPPGSVYRYGFDVVWEQMRRERGLLETVVSRLGSADSLMVLNSMMFINSLLSHA
TDTHWEEFTSELERLNVRKAVVRLMSSHVIDDLTSSILDFQANEVRFILRRKHEPVDPLE
NLEHFNTLRYIWQMSKVEEERNLENEGELHKWRKLGFESEDVLQEFVGVGVLGLDCLKYF
VQNDPDSFAKVVLEQLNRPEERRCPVAKASNEVVELLCEHWEIFAPGYSTSTTFQPFFLN
FYKVHVLTTQFILRFVAVSPEAAEHILINTLRANSMWNESGAAVDDFARVVALARSQVKV
ALRQENVRAWHEVEHDFLESDYRAVRDRQMKELENEDDLLSKVPVRNLRAKLYKESYEFV
RQQRIQCLLQGTWFVNAIPLASTSAKDASRRPTRPWRFIRLDNGLKYLHYVDSAVKFQVR
SGLEDLPERIDISLITEIATGTCGPPPNVLREHMDVPPSSPLQPAPLSFSLLTPEGSLAD
QIAPDQARWADWTDGLNMLRRDGGHVATQETAGFVQALTEIGLKIKMLDLSGEKVEIPSG
LLSGPPPPNNDFFFSDLSFDTQIEQADKENRVWWSFEYFPPRTAQGLQNLLDRIERMRAL
GPEFIDITWNAGGRTSDLTSEMVKTCQSHIGIETCMHLTCTNMPKDKVDIALKEAKQHGC
RNILALRGDPPLGKDEWEATEGGFVHGVDLVQHIRTHYGDYFDIAVAGFPQHMLLPPDEL
AFEMKCLKDKIKAGVNFIFTQMFYDIEIFISWVHAVRAAGITIPIVPGIAPLQTWNGFMR
ATSLAKTIIPKHFMDALEPYKNNDEKVRAIGTKLVAEMCRRILQENLGIRGLHFYTMNLE
KATKMLLEELNLVPRVETIKPLPWRQSLTPNRRTETIRPIFWANRTKSYIARTENWDEYP
NGRFGDSRSPAFGELDGYGVWLKQSKEEALRIWGSPTTFSEIAELFARFCQSNLPALPWS
DQAPSAETRVIDEQLAHMNRLGFLTINSQPAVNGARSGDKVHGWGPSNGYVYQKAYLEFF
VEPGLLAALLPHIERDGNITYYAINKRGDLRTNTHSEGPNAVTWGVFPGKEIIQPTIVEA
VSFMAWKDEAFELGRQWARFHEPDSPTRKLITDLMETSFLVNVVHNDFKDPDAIFKPFFA
AGESYKAQQSSTSDARINGVH
>A0A7X0MS01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium soli|TrEMBL
MDTPAAKAPFKLSYEFFPPKSDEMQTQLWETVDALAAFKPEFVTMTYGAGGSTREPTLAA
VQRMINDAKLQTAAHLTCVDAAREEVKSVVEEYRAAGVRRIVALRGDSSAGVGAAYTPHP
DGFSDTADLVRMLVEYGDMDISVSAYPEMHPESPSMAADIDTLKRKADAGANRALTQFFF
DNEVFERYLEAVHAAGITIPIVPGIMPIQNLTQLKRFAGRCGATVPAFLDARFEGLDDKP
DDRAKVAADVAAEQIADLMRRGHDHFHLYTMNRVPLVSGVLERLGRHPDKNANVGNAA
>A0A1F0KCU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC065E03|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKDLFAHQPNFEVN
>A0A261EVQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bombiscardovia coagulans|TrEMBL
MHAPIFSLEVFPPKRNTTVGTIYDTLDGLESLHPDFISVTYGTGRYADRTATARICATIR
GEYAIPTVAHLTSQYADQVAVDEALDMFECAGVKALLLLRGDRTDGKEPLGVYQHACDLI
TYVHEARPDFLIMAACYPETHPEALSVEEDIRHLKEKVDAGAGHLISQLFYDNSDFMNFV
GRARAAGIDVPIEAGIMPITRAGQVRHMSETCGSCIPPAVTRLLEKWGNKPKSLCEAGIV
YASQQISDLVSQGVDGIHLYSMNHPVVTRRIWNNVQSLFEEAL
>A0A1S2PUE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces colonosanans|TrEMBL
MALGTASTRTDRARTVRDMLASGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVDHSLAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDTDVAHFVD
KCRAGADYAITQMFFEPESYLRLRDRVAAAGCVTPIIPEVMPVTSVRMLERLPQLSNAAI
PAALKERILAAKDDAAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYDSLG
LHHSQQA
>A0A315E3P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. 2KL-17|TrEMBL
MSGLKLPISLEFFPPKTPEGAHKLSAVRQQLYALKPEFCSVTYGAGGSTQEGTFATVGAI
LGEGVSAASHFSCIGATKASVRAELATLRAMGVKRLVALRGDLPSGYGAGGEFHYASDLV
AFIRAETGDDFHIEVAAYPEIHPQAKSPEADLQAFVTKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGYGDDIDSIKAFGL
DVVADLCEQLVNGGVPALHFYTMNQSAATTEICSRL
>A0A1Q5ISX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02009|TrEMBL
MRPTPVDPTFSFEFFPPKSERGERTLWEAIRRVEALSPDFVSVTYGAGGSSRDRTIEVTK
RIAAETTLRPVAHLTAVGHSVAELRAIIGAYADAGVRDVLVLRGDPPGDPRGPWTPHPRG
FTYAHELVALVRSLGDFRIGVAAFPEGHPRSAGPADDLAHFVAKCRAGADYAITQMFFDP
EDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAKDDPAA
AYRIGVEHATAMGLRLLDEGAPGLHHITLNRSTAALEIHRTIMSARSVVHV
>Q13T38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia xenovorans (strain LB400)|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLATLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFCIEVAGYPEYHPQSRSPRQDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCRRLIDAKVPGLHFYTLNGAAATKAICERLNV
>A0A2D8SLZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Owenweeksia sp|TrEMBL
MKVIEHIKQAKETIFSFEILPPLKGQNIRDIYNTIDPLMEFKPPFVNVTYHREEVVYKRL
NNGLLEQKVVRKRPGTVGICAALQNRYKIDAVPHILCGGFSREDTENALIDLDFLGIENV
LALRGDSIKGETYFVAEKNGHTFACDLVGQISDMNKGIYLDEELKNNTPTNFCIGVAGYP
EKHFEAPSINNDVQNTLKKVQQGAEYIVTQLFFDNTRFFEYVEKCRQVGISVPIIPGIKP
IATKRHLSLLPHRFHVDIPDELVKSVVNCRDNEQVREVGVEWAIQQCKELKEAGVPVLHF
YSMGKVDNIQTIAKAVF
>A0A2T5GND3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas aurantiaca|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGISFEFFPPKTEKMETQLWEAIRTLEPLAPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGDPNADIDNL
KRKLDAGASRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKSDVTVAAA
>A0A840R5P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zhongshania antarctica|TrEMBL
MANRYSFEFFPPKTEVGRAKLKDTRSQLAALNPEFFSVTYGAGGSTRDNTRDIVLETKKA
GLSVAPHLSFGGDEESEILTLLNDYKAAGIDRIVALRGDIPSGMGATRQVYAKELVEFIR
KHTGDHFQLEVAAYPETHPDAKNHQADIHFLKAKLDAGANSAITQYFFNADAYFYFLEDC
EKAGIDKPIYPGIMPITNFSNLARFSRNCGAEIPRWLAQKLEGYGDDQQSIVEFGAEFVS
ELCHILMEGGAPGIHFYSMNQVEPIKSIAEAVMSSHPAG
>A0A418XJ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cavernicola|TrEMBL
MSQERRYSFEFFPAKTEAGHAKLLATAHQLASYQPDFFSCTYGAGGSTRDRTVNTVLQLD
SETKVQTAPHISCIGDSKADLRVLLSHYKQAGITRIVALRGDLPSGMGMSSGELRYANDL
VGFIREETGSHFHIEVAAYPEMHPQARNFEDDLANFVRKAKAGANSAITQYFFNADSYFY
FVERVRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIESIQSYG
EQVVSEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A6M4WYM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces asoensis|TrEMBL
MALGIPSTRADSAVSIRDLLARGGRSYSFEFMPPRDAAAEAGLWTAIRRLEALSPAFVSV
TYGAGGSTRGRTVDITGRIAQETTLTPVAHLTAVDHSVAELRNILGHYADQGVRNILALR
GDPPGDPLGPWTRHPSGIRYAAELVSLIRESGNFCVGVAAFPEMHPRSSDRDSDIRHFVA
KCRAGADYAVTQMFFDVEDYLRFRDRVTAAGCETPIIPEIMPVTTIRSLRRIPTLSTAAV
PARLAERMLAVQEDPKAVRALGIDHATEMCRRLLAEEAPGLHFMTMNFSTVTAEIYQNLE
LHG
>A0A6M8V793|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium|TrEMBL
MKVIEHLNNAVNPLISFELIPPKRGGDIRGLLSVLDDISKFNPPFIDITSHAAEVFYEET
PTGIKKKVKRKRPGTLGICALIQNKYNIDAVPHVISKGFTREETEDFLIELNYLQIQNVL
AIRGDDSGYEKPIPEGKSKNPYAVDLVKQIINMNNGKYLEDSLLDALPTDFCIGVGGYPE
KHFEAPNLKTDIKYVKEKVDAGAEYIVTQMFYDNRHYFNYVDQCREIGIDVPIIPGLKVL
TSKAHLTSVPKNFFLNIPDELSDEIMAARPEQVLDIGVEWAAKQVEELLNANVKSIHFYV
MQNSKPILKLMERLKL
>B1YD20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta)|TrEMBL
MEVIAEITPLRDRDKVLRKLEAIKPYVEKVDIPESPGGKPTAHSLAVGVLAKQLGLEPIV
HIRLLDVNKTGFKSLLGGAHILNIKYVVVLQGDPPAEGKPVGEVATEDAVAEAKKMGFVA
GALLSFKRNYRERIAQLGADFYLALHLTDPRQLDGLPPAVYPYIMIKTGNNAALLERLRQ
TAVDLQQALKLVEELDGLVPGVVLSAPGDFEALLAALREVKRRRS
>E1YJB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacterium sp|TrEMBL
MKSGSNLEKVLAAGHFAFTGELGPPRGTDADEVRKKASYLKGMVDSVNITDNQTAVVRMS
SWAASIIAIQEGLEPNYQMVCRDRNRLAMQSDILGAYALGIRNMLCLSGDHQKFGDHPQS
KGVFDIDSMQLIGMVKRMRDDAKMLGGTEMEHPPKMFIGAASNPFADPFEWRVHRLAKKI
KAGVDFIQTQCIYNMDKFRKFIKMANDMGLTEKVYILAGVTPMKGVGMAKYMKNNVPGMD
VPDELIKRLQGVDKKMQADEGIKIACEQIEEFKEMKGVAGVHLMAIEWEHKVPEIAERAK
MLPRPVV
>A0A3L7BLB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. CV4|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTEAGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVSVTERIATDTTLLPMAHLTAVNHSVAELRHVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPQGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFEADDYLRLRDRVAAAGCDTPILAGVMPVTQISTIERSVQLSGAPF
PPALAARFERVADDPEAVRLLGIEQASEMSRRLLDEGVPGIHFITLNRSTATREVWQNLK
VGARM
>A0A316EEK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcicella aurantiaca|TrEMBL
MFLDRIKSKESGILLYGITPPKSQVEPQKVVEIAEKTLARLHSLDIDALVVYDVQDESAR
TTEERPFPFLSAHDPFEFAKNHLHSLNIPKIIYRPASKFTQEELSVWVDDVIAHDFSPVF
VGVPAPDFVPITTLPQAYDVWRKHEEKSVIGAVMIPERHAVLNDEDQRILDKMSSGVSYF
ISQCVFNVDYAKRVVDDLAKTCTAKNIEIPTLIFTLTACGSIKTLHFMEWLGIHIPEDLK
EELRNSENILERSVDVCITIADELIKYCSEKNVPFGFNIESVAIRKDEIEASIFMVNKVG
EMMKEIGIRK
>A6XMY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Triticum monococcum|TrEMBL
MAGPSSPSSTSRPRRREGVENLFERMDRMVAHGPNFCDITWGAGGSTADVTLDIANRMQN
MVCVETMMHLTCTNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDKFVQVAGGFSCAL
DLVEHIKAKYGDYFGITVAGYPEAHPEVILGEEGATEEAYRKDLAYLKRKVDAGADVIVT
QLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTKIPAEITAALDPI
KDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNLGLIEESKLSRTL
PWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWGDSRNPSYGALNDHQFTR
PRGRGKKLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPETTIIDDQLVKIN
SKGFLTINSQPAVNAEKSESPSVGWGGPGGYVYQKAYVEFFCAKEKLGQLIEKSKAFPSL
TYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGWA
CLFPEGDSSRELLEQIQKSYYLVSLVDNDYISGDLFAAFKEI
>A0A5B8E8K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum seropedicae|TrEMBL
MSTSTHNFSIEFFPPKTAEGAEKLRATRARLAALQPKYFSVTFGAGGSTQQGTRDTVLEI
VSEGHEAAPHLSCIGSSRASLRAILEDYRANGIKRLVALRGDLPSGYGAMDQASSEFRYA
NELVEFVRAETGDWFHIEVAAYPEMHPQARSPQDDAQNFARKVKAGANSAITQYFYNADA
YFRFVDEAARLGATVPVIAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTESIR
AFGLDVVTQLCERLLAGGAPGLHFYSLNQAGPTQAIWQQLVK
>A0A3A5WSE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AF29-11|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>N2JAH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. HPB0071|TrEMBL
MTRTTPNVSFEFFPTKTEAGHEKLLNTARQLAGYSPEFFSCTYGAGGSTRDRTLNTVLQL
DSEIRIPTAPHLSCVGDSKAELRDLLIRYREAGITRIVALRGDLPSGMGISGGELRYANE
LVSFIREETGDHFHIEVAAYPEVHPQARNFEADLANFVRKIKAGANGAITQYFFNADSYF
HFVDRACKLGADVPIIPGIMPITNYSSLARFSEACGAEIPRWIRKQLEAYADDVKSIQAF
GQEIVTDMCERLLAGGAPALHFYTLNQAEPSLAIWNNLGFKS
>A0A4Q0P0H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leeuwenhoekiella aestuarii|TrEMBL
MKITDHIKQANGKTLFSFELIPPRKGKSIQELYNNIDPLMEFKPPFIDVTTSREEFVYIE
KDGLLDKKVTRMRPGTIGICASIKHKYDVDTVPHVLCGGFTKEETEYMLVDCHYLGIHNL
MALRGDAMREEQYFKPTPGGHEYALGLVEQVVEMNKGHYLNGMVETSDCSDFCIGVAGYP
EKHLEAPSLKTDLKRLIQKVEAGADYVVTQMFFDNKKYFEFVDLVRAEGIDIPIIPGIKP
IAVKRHLQLLPQVFKIDLPQELIESVESCKSNADVRQVGIEWAIQQSKELMEGGAPVLHY
YSMGKSDNVKAIASELF
>A0L1B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. (strain ANA-3)|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETNLVAAPHLTLVDASDEELLDLAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAADLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPSWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPKAV
>A0A1G7VCR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium pygmaeum|TrEMBL
MSKTTHVMANPRAAVELVQDYSLEMTGKDVPALMEAKDSIPAGTRINVTFLGNEDLEMRV
SAAKAVREMGFIPVPHISARRLSSRQQLEEFLSRLQDVGATDSVFVVGGDPATPEGPYEG
AFDVIHTGLLLDYGVKDVSIAGYPEGHPDIADDVLWRSLDEKVHSLAQQKLHTTVLTQFA
FDTDPVVAWIDEVRGRGIHGTIRIGTPGPAGIKRLLGFARRFGIGANAMIVKKYGFSLTN
LMGTAGPDIFVGDLASLLASDASVSEGTEVAAPASGPTTGPVKLHFYTFGGLLATADWAR
EFTRTHS
>A0A3M0FVZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dokdonia sinensis|TrEMBL
MKVRDHISKAVEAHKTEFSFEILPPLKGQNIDTIFKNIDPLMEFNPPFIDVTYHREEYIY
KEREDGLLEKKVVRKRPGTVGICAAIQNKYDVDAVPHVLCGGFSKEDTENFLIDMDFLGI
ENVMALRGDAVKSETYFKPNKNGNVYAQDLVEQIIDLNHGKYLDEDLLNSSQTDFCIGVA
GYPEKHLEAPSMESDIHFLKKKLEAGACYVVTQMFFDNQKYFDFVEKCRAAGITKPIIPG
LKPLATKKQLNMIPQRFSVDVPDALVMEVVNCKTPDAVRQVGIEWCIQQSKELKAAGVPV
LHYYSMGKSDNIRQIAEAVF
>A0A517I779|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus brevis|TrEMBL
MTTRKKDLRAYLKDHLLVGDGAMATQLHGLGVPVGVSFEELCLSNPRLVHEVHTSYYQAG
ARFLETNTYSANRDALSRYGLEHKVARINRLAVAIAREAAQDDAYVAGSIGSILAGRVKK
KVLDEFRDQYEEQAIALLHAGVDGLILETFVDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYALTDAFSELKAAGADVIGLNCRLGPAELLRSFENTVIPEDALLSVFPNAGRLG
MTDGEYAFKSSPEYFGQSALRLREQGVRLIGGCCGTTPAHVKAIADALESLEPQARVNPT
IVAGDRPSISVQNTREREKPSIVERVKTATTIIVEFDPPRDLDADQFLHGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKSRHGIDPLLHIACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMDAAVARLEKKVEAGADYIMTQPVYDAESIRNVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSTEALERMKKVQGEAARQEGIAIAKELVDTAVRYFNGIYLITPFNYYE
MAAELIQYTRQQSSLVKLAQT
>A0A6N7G7Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola sp|TrEMBL
MSFQPLPKAPRTRRAVAPLLAAPRYEILPLPRVLEATEQLPAGSVVTVTASPHKGLHATI
DVAEDVAAQGMRAVPHLAARQFRDSAELSDVLDRLDAAGIGEVFVVGGDGTHPAGDFGDG
LALLHGMADLGRLPAEVGVPSYPEGHHAIDGDTLWTSLRAKQEFATYTVTQLCFDADAIC
RFAAAAQRNGVTLPVVVGTPGVVDLTKLLRVGLKIGVGDSLRFARGNASVAGKLLRPGGY
RPDGLVRKLASRVASGDCTLAGLHFYTFNHVAATARWVRNTHRRAA
>A0A7Y6YN16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MDHTISQPYSAPPEGHVSHSRLERVLRSGRFAITAELNPPDSADPADVYEAARPLGEVAD
AINATDASGANCHMSSIGISALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAAMGVSNVL
CLTGDGVGVGDQPGAKPVFDFDSLSLLRTIKTMRDERRFLSGRTIKNPPQLFLGAAENPC
IPPYDWRPERLAKKVEAGAEYIQTNYIYDVPLFEKFMARVRDLGLDKKVYILAGVGPLAS
ARAARWMRSNVPGIHVPDAVIDRMEKAEKPGKEGKKICIELIQQMREIAGVSGVHVMAYR
KEHEVSAIIRESGVLASRKR
>A0A7V1D4N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodospiraceae bacterium|TrEMBL
MTEQSPQFSFEFFPPKSSEGMEKLKATRDELMTLNPKYVSVTFGAGGSTQQGTIETIQEM
LNAGLDAAPHLSCIGSTEANIRELLNLYIDMGVKRIVALRGDMPSGMGEAGELHYANELV
EFIRKETGDHFHIEVAAYPEFHPQAKSATADLDNFARKVKAGANAAITQYFFNLDAYLHF
IEECAKRDVDIPIVPGIMPITNIKNLSRFSDMCGADIPRWLRLRLEAYGDDLESLKAFGL
EVTTELSQRLLDAGAPGLHFYTMNQAGPTQTVMSNLS
>A0A1B8CLI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. WSF 3629|TrEMBL
MHIKDMLNQGEQAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHA
QLTCEMVSVAQSVYGLETCMHLTCTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEK
WVATDEGFQYARDLVKYIRKTYGNHFDIGVAGYPEGCDDQTDADLLLDHLKEKVEEGATF
IVTQMFYDVPNFLDWVRKVRAKGIIIPIIPGIMPISTYASFLRRCNHMNAKIPPGWIEAM
EPVKNDDAAVREIGRGLVTDMCRSILESGINHLHFYTMNLAQATRGVLEQLEMLPSEERP
LKQALPWRQSLGLGRRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGEPKSVKDIANVFLRYLNADIESLPWSEAPISNEADVIKNQLVE
LNERGLLTINSQPPVDGVKSSHPVYGWGPLNGYVYQKAYLELLVAPELIDELLDRIARDP
EVTYYAVTKSGTLRTNAPSDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHDASSPSRNVIQRVMETFYLVNIVHNDFHQRDALFSLFEGLTVPNIDKAAEGTVAPA
PTPTPPAAAAPATNGDKVEDAPPAIVSNVLPVA
>A0A520ZJA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MSEPTVSFEFFPPKSLDASFQLWEALRSLRHLDPAFVSVTYGAGGTTRELTHEAVETIRD
HTGVEVAAHLTCVNASKDETLEIAQRYAAAGVSKIVALRGDPPDGSEAFEAHGDGFASSV
ELVEALASVGTFDIIVGAYPDPHPEAGYEDADVDWLKRKVDAGATSAITQFFFEAETFLR
FRDRCDAAGIDIPVLPGILPIQSWNGVRRFAERCGARIPDTLALAFEAAERDERSDLLAL
TQCTTLCTRLLDEGAGHLHFYTLNKPDLTREVIHALGLAPAAVLENVA
>Q9L5C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESA
>A0A078RCZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus str. 3775 SL|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKDGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVEAGADYVVTQMFYDNRKYVDFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAMKCKDDKEARALGIEWCINQCRELIAYGVPGIHF
YTVGAVDNVKEVATAVY
>A0A2E3FH04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTVPAISFEFFPPQNLEASFRLWDTVQVLAPMAPRFVSVTYGAGGTTRDLTRDAVATIHK
HSGLNVAAHLTCVNATRAETLAIADQFAEAGVTDIVALRGDPPKGTGAFQPHADGFASSV
ALIESLAETGKFNIRVGAYPEKHPEAASSAADVNYLKRKFDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIIPGIMPIANWKGARNFARRCGATVPAWMDEAFDKAARDGREDLLAT
ALATELCSELIDGGVDSLHFYTLNRPELTRDVCHALGVTPKTTLENVA
>A0A2E7VFA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutales bacterium|TrEMBL
MRFIRDIHAKNQAAGKPTISFEFFPFKTPKGETTFFSTTLPALMASKPDYASVTYGAGGG
TREKTLEIVERIQNEFGLTTMAHLTCIKHTREEIDYILDDAAKRGIQNILALRGDPPPGE
NWSQTEGGFEFASELVDFLLKRGGFGIGVAGFPEGHIDCAGGREEDWPLLVNKINHGVDL
VITQMFFDNADYFRLHDYLKEQGITAPLFPGIIPVANAEQIKKFSALCGATLPKAFALRL
DELGDDADAVSEYGIEYATAQCRELLDRGAPGLHFYTINRSKAVLRILANLGLA
>A0A503TV83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-3-12|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHQVDAVIREFTDMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEPDVA
GSAAA
>A7NND0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseiflexus castenholzii (strain DSM 13941 / HLO8)|TrEMBL
MRSFSEFQRRLQAGQIVVTGEIAPPRGASRATVERLALGLRDAVDAINLTDNQRGLGRMS
ALGAGIIIRQLGLEPIVQMTCQHRNRIALQADVLSGAACGITNFLAMTGDHPKIGDHPDA
KNVLDLNSFQLLKMLRTMRDEGKFQSGVALTEPPRFFLGGVANPNIERVARLERKIQFGA
EFIQTQILFDLDRFRQWMADARAAGLHQKAYILAGIMVVKSAQSARFLRDHLPGSRVPEW
VIERMERADHPEEEGIAIAAELTRELLAIEGVRGVHVMSVGWTKAIPQVVERAGLLPRPP
LPPDNPNDD
>A0A0Q5VE61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus sp. Leaf369|TrEMBL
MTGTVRELLAEGRPTWSFEFFPPKNAASEAQLWTALRELERLRPSFVSVTYGAGGSTREG
TLAVTERIATDTTMLPLAHLTAVDHSVAELRNVVSRLAAAGVRNVMALRGDPPGLDPQAD
WVAHPQGLRYAAELVELVKDVGDFSVGVAAFPESHPRSPDAEADADMFVAKCRAGADFAI
TQMFFRVEDYLRLRDRVAARGCDVPVLAGVMPVTSTKQIARIVQLSGQAFPADLAERFAA
ADRDTPEAKQAQRDLGVEVATEMCRELLAEGVPGIHFITMNRSTATREVYAALAELAPTA
>A0A512I9U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria turfanensis|TrEMBL
MRRPPDRTAPPPALSYELYPPRCAASAETLLRTIEELEPTRPDHVAVTYSGDAPRRAGSL
ALLDHLLARTGLRPLAHLTCVGSTRAELEETVTSLLHRGVRGVLALRGDLEPGAEPGELA
HAGDLVELVREVEQRHTASLAAGRLAVGVAAYPTRHPESPSFRHDIEVLLAKQRAGADFA
ITQVYFRPQRYERLVVAARAAGVTIPIVPGIMPVTEPRRLATLCRLAGLRPHPGLAAALE
DASGPAERHRAGVAFATRLARAALDAGAPGLHLYTFNEHRAALDLLERVDLPRVPHQPAA
LPDLLPA
>A0A1Z3HPF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomicronema hongdechloris C2206|TrEMBL
MVAAVYCALRHGPSYSCPHLIFLTPCLIAIVASSTPLSPLGYQFRTAVKAGDFLVTAEVT
PPKGGDPQRMVSMARCLRGRVHGVNITDGSRAMLRMASLAAAAILQQAGIESICQMACRD
RNRIALQADLMGVHALGIRNLLALTGDPVKAGDHPDAKSVFDLESIRLLRVINQLNQGVD
SHGKSLPDGATDLFAGAAVDPQSHSWSGLQRRFNRKLDAGAQFFQSQLITDFERLEKFMD
QIAVGCHRPVLAGIFLLKSAKNAEFINRHVPGVQIPEALIQRLAAASDPLQEGMQIAAEQ
IRIARQLCQGVHIMAVRREDLIPPILDLAGVAPLEPSPSHPNPA
>A0A1H7ZB75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium taichungense|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTTGGHASAMDLVHQINNLGRGKYLHNEDQECEEHNKFCVGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVKKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEELITEVENAKNNEAVKQIGIEWAITQCRELLDFGVPVL
HFYSMGKSDNIKKVAGALF
>A0A1C3CUL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter celticus|TrEMBL
MSLFIDSLKAQNFCVLVEYLCTMKVALPVRSSLAGYPVYMTWADRVQTDEDPSPLDVAQN
APEGTEQVLHYSGKGRDIANFEQFLKQAKALGLRNLLLLSGDKLKNHNDGHLQPELRSRY
LESVNMVMAARRDPSLNIGVAFNPFKYAEAERDAQYFKLQKKIQAGADYIITQLGFDLDA
LKQAKKFLESVHIQRPILACVMPLTLARANFMVKHKVAGIVITPHMLNVLAEEKETGFTE
RVYLRCALQILICKQLGFAGIHLSACHKAEEQMRLERYLEEYGHLELDALELLWNSFWQV
KTGKEFMPTLTSYSRQPTSSQIIKYQHLHFMHDAFFESKIAKGVGKLIFKAQFWEQATVA
KALLKTEFVSKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDREC
IHSVKARLAKAVDQTIVLKEKLIPTVPIEIRGTSSWKNWYV
>A0A1H4JB31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas saponiphila|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLAGYNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLQQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A1V0Q0B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum sp. P5|TrEMBL
MGILQFGKRIDRRTVAGPLTGFVQGYSVEVMPRTASKIDDFATLLPAGTRIYIAHLDGTP
IEDMVATAARLRAEGFEPMPHFPARSIPDAATLADWIARYQGEADVRQGLILGGGIPHPR
GAFHCSMQLLETGLFDNAGFSALHVAGHPEGSRDIDPDGSDRLVLEALRWKQAFSERTDA
EMAIVTQFAFEAAPVIAWADRLRAEGIALPIRIGVAGPAKLQTLVKFAVACGVGPSLKVL
QRRARDVSKLVLPFTPDEFLTDLATAAAKRPDFPIEGVHFFPLGGIKTSADWLAGHGLAP
AQAS
>A0A1W9MZQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium IS3|TrEMBL
MTTNVKTPSRLEKILRAGHLAVTSECGPPRGTDPEAITKKAEMIRKHVDAINITDNQTSV
TRLCSLAACIHIRLMGLEPILQMVTRDRNRIALQSDILGAASFDIHNMLCLSGDHQSFGD
CKQGQNVHDIDSMQLLQTVRYMRDEGKFLGGDDIKRPPRMFVGAAANPFADPFEIRVPRL
AKKIAAGAEFIQTQCIYNLNKFEEWMRLARERGLTEKVFILAGLTPMKSAGMAKYMKNRV
PGMDVPDEVVKRLAGVSKEKQPEEGINICVESIQRLKECRGISGFHIMAIEWEEKVPEIA
ERAGLYPRPVLN
>A0A4R2BR04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium americanum|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMEIQLFQTVADLSVFAPAFQTVTYGAGGSTKAR
SLTTVKRMIGEMGLENTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGSA
YEPFPGGYESSAALVKALRARGDFEISVSAYPEKHPESADVAADIDMLKRKVDSGATRAL
TQFFFNNDDFERYIERVRRAGVQIPVVPGILPINNLTQVIRFAGLCGSKVPEVIISRLAH
LDDQPEERFKEASHIAAEQVVDLARRGFRDFHLYTMNRSPLIAAVCDLVGYQRRPARPTA
APSYPAVATA
>A0A2U3KYM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacter sp. SbD1|TrEMBL
MSIVLFVTFFWFRLVRVRDIDMLRVFQLDLTDPDHFVVTLELVPGREASGRAVDSVVGIA
RDAFDDGRVSAVSITDNPGGNPSLSPDVLGHNIFEIGMDVIVHFTCRDMNRVGMESRALQ
LAMMGIKNILALNGDYSGRGFGGQGAPVFDLDSVQLQIMLGLLSERINASGDPEGFFTGC
AVSPFKRTEGECFAQYAKLGRKAAAGAQFVITQLGYDARKFKELIQIQKAMGITLPSLGS
VYVLTPKVAGIINAGKVPGAVVTEALLQRVQDEWRDAASGRQAAIERAARLAAVLKGLGY
SGIHIGGIHRSFDMVGSILDRLAVIEDQWKEFLADFDFPLPGGFYVFPPQSEVGPETPVF
GLHPPRIGLLERLRYSLLRRVHSTFFDHRHPLGSIYRKLSKQVDAMPGGQLLMHLAEDIP
KRVFLECQKCGDCAVQHVGFLCPESQCAKHIRNGACGGSRDGYCEVFPERPCVWDRAYRR
LVNAKRTRQMCEGCVPPRMWELNQTSSWLNFHLQRDHQGGYNEIAQRCRLIKCPPLTR
>A0A3T0E6W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycocaulis alkaliphilus|TrEMBL
MPKDRLAPATGVPQISFEFFPPKDEAMEERLWNSIARLAPLNPLYVSVTYGAGGSTRDRT
HRTVRRIVEETALSPAAHLTCVNAARDEVDAVIRDYWSAGVRHIVALRGDPPGGVGERYE
PFAGGYANAAELAAGIRAVGDFEVSVGCYPEKHPESASFDHDIDLLKAKIDNGATRAITQ
FFFDADVYFRYLDRVRSAGITIPIVPGIMMQSNFEGLVRMAGLCGATIPARLFDLFDGLE
SDPGTRELLTANVVADLCHDLSDHGVDQFHFYTLNRAELALATCRLLGVRPVEMAA
>A0A2P9EZF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MA5143a|TrEMBL
MLATGRTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRAGTVRATEQ
IAADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMADWVPHPQGL
TYAAELVHLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFFHPD
SYLRLRDAVAKAGCETPVIPEVMPVTSVKMLERLPQLSNAAIPDALKERIVTAKDDPAAV
RSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGLHHPPRA
>A0A4Y3TU83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter peroxydans|TrEMBL
MPFLPGAGLSAELLNLGPLGPDLSTRGPEGDVAVSFEFFPPKTDKMAAALHQTAQDLAPL
KPRFVSVTYGAGGSTRERTLAATAVLAREAGVPVAGHLTCVNATRAQVDDVARAYWAQGV
RHIVALRGDPPGQAGQAPGGRFTPTPGGYDNAAGLVRGLREIAPFEISVAAYPENHPEAT
SAQADLDNLKAKLDAGATRAITQFFFEAGTFLRFRDRAAAAGITAEIVPGILPIANIEQA
YTFAAQCGTHIPLWMRRMFDGLDAQPETRALVTTAVAGELCRQLRAEGVTQFHFYTLNKS
APSAALCRLLGRHPILENVAA
>A0A1D9ECG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. glycines str. 8ra|TrEMBL
MPSGASTITDTYSLEVSVKDIGALTNAAPRILPGSDMFIPYLPGQTEAARLAAAQRVRRL
GFEPVPHLSARRIGSLEELQAVVARLVGEADVTRCLVIAGDPSTPKGPFADSVSLIETGV
FERSGIRTIGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDADIVMTW
LEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGNAGPDR
FVDRLVSRLTEAHGDVRLHLFPFGGIAQSVEWVAHYRSCEASQDRVSSVAAD
>A0A4U9J160|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leclercia adecarboxylata|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
CRRAAVSRICTRPIWWRC
>A0A2R5EKM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus agaridevorans|TrEMBL
MLLLLIDYCRLTALEAKKYMLKEKILGKEAGILTYGMTPPKLTNTPHKIAEISQKQIERI
NDLDIDALILYDVQEEAERVEEQRPFPYLPTIDPEMYSDRYFNQLRVPQIIYRCVGKYSE
EQFVNWVKADAERERYSVYVGASSSRQAVNLDLSKASKLSKRLNSKLTFGGVIIPERHMK
KNDEHIRVSNKIKNGCTFFVSQATYNVEASKNFLSDYFYYCTNNGMEMVPILFNLAPCGS
EKTLEFMKWLGISIPSWLENDLKYSNDILEKSIRLSQSIFEDILDFALEKGIPVGCSVES
VSTRKLEIEASVQLVRDIKCMLDKKLRRQQ
>A0A7V5MID2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacterales bacterium|TrEMBL
MFETFCQRLHSQHPFITVEITPPHGASIDTIIGTIDRLKLQEKVSGFSVTDNPLAKLKMS
GVLSAIKVQERFQKPVIATMSMRDKNKLSLQSSLLGANDFNLRAILALTGDPAKLSDQPE
VKGVVERDSTLLLSIIYHLNKGVDYSNKELNPKPKPIYPFAVSNAYSKDMRRIKKKILKK
LNYGARGIITQPVYDLENAKELLEIFEECKAESVRETAKEAELIIGQFPVVRARTVNFIS
DKVPGITVPKTIIDEMNLASMDGEAKEQEVGFAISKQVFDAIMQLHPKMHLMTHNRFDLC
SELIGDNY
>A0A6G8J7B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurellaceae bacterium Orientalotternb1|TrEMBL
MSYAKEIDLLNQSVADLNGKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKSIQQETGIIAAPHLTGIDATPDELRAIAKDYWDSGIRHIVALRGDEP
AGYAKKPFYASDLVALLKDVADFEISVAAYPEVHPEAKSAQSDLLYLKQKIDAGASRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMHKMYQGL
DDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGMRPE
>A0A1A5YHS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus oryzae|TrEMBL
MGTYLYQLGFPIGVSYEELNVLRPEVIQNVHRLYYEAGARIIETNTYSANLVKLAKYGLE
DQMEAINRAGVAIARSAVGEDAFVIGSIGSVRDGKLNNVRTSKVEEAYERQMTALVEAGA
DGLLLETFYDLKEMKLALSIARKIGDIPVICQFAVEDSGRTRDGVALADAFQQLKKLGAD
VVGFNCHSGPNGILKAVESIEGPVHLPLSVYPNAGIPDYVDGKYSYSAGAQYFGECARRF
ADRGVKIIGGCCGTTPEHVAAMAAAIEGYAPQSEAAIQRPKAAVAESAPNQASTAGKFSR
TGGDAPQTIVDLVKQRHTVIVELDPPRDLDISRFMAGAAALKAVNADAITMADNSLAVTR
MSNLALGALLREQVDITPLVHIAARDRNLIGTQSHMMGLDALGINHVLAVTGDPARFGDL
PDSSSVYDLTSFEMIRMIKQLNEGTAFSGKPLKQKANFIVGAAFNPNVKHLDKAVQRLER
KVSSGADYIMTQPVYDPELMVRIAEATKNIGVPVFIGIMPLANGRNAEYLHNEVPGIQLS
DEVRKRMAGLEGEAGRAEGVRIAQELLDAALPHFNGIYLITPFMYHDMAVQLTRYVWQKT
KK
>A0A4R1APZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus praedii|TrEMBL
MSFLERMKNEILIADGAMGTLLYSYGTDCCFEELNISQADQIQQIHKAYIHAGANLIQTN
SYAANYIKLQRYGLEDNVKDINTAAVRNARKAAGKDSYVVGTIGGIRGMKPNMVVLEEIK
RSFREQLYCLLLEGVDGILLETYYDIEELENVLQIVRKETELPIIAQVSLHEVGVLQDQT
PISKAIERLENLGADVVGLNCRLGPHHMLETLEDIPLPNRAYLSAYPNASIPAYTDGKFH
YEGDPNYFRQSAKAFRNQGVRLIGGCCGTTPDHIQAFASELKGLPPISEKLIKKREQIRI
SDGNLPVREYTPLEDIVKMRSSVIVELDPPKHLNTAKFFEGVKAFKEIGIDAITLADNSL
ATPRICNSALGYRVKKEIGMRPLVHITCRDRNIIGLQSHLMGLHTLGLYDVLALTGDPAR
VGDFPGASSVYDLSSFELIKMIKQFNEGISVSGKHLQEQSVFSVGAAFNPNVRSIEKAVQ
RLEKKISYGADYFVSQPVFSEKKLLEIHAAVKHLERPIYIGIMPLTGSKNTEFLHNEVPG
IKISEEIRSRMANLKDDPVNAAREGVAIAKSLIDAACELFNGIYLITPFMRFDLTAELAL
YAHEVSAKITRRNENAKISIN
>A0A839QM70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paeniglutamicibacter cryotolerans|TrEMBL
MSMTLSTALPSLSYELYPPASAAAAEDAHHSIVELESTDPDYVSVTYSGTEARRKASLEL
IGHLINNTRLRPLAHLTCVGEDRASLESLVQHFVSIGVRGVPALRGDLPREPGAWRRELP
FARYLVELIRDVEARNTAALGAGRLAIGVAAYPMRHPESPSFEHDVEVLLAKERSGADFA
ITQVYFDPLDYTGLGVAASKAEV
>A0A2M7GN11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacterales bacterium CG15_BIG_FIL_POST_REV_8_21_14_020_59_13|TrEMBL
MTCEPQTFAFGRTSAPTVSFEFFPPKTDAMEARLWETVEKLEPYRPDFVSVTYGAGGSTR
ERTRNTVKRIRKETGLKAAAHLTCVGATRDETTEIIHDYKAAGVDHIIALRGDPPAGVGE
TYTTHPGGFGCTSELVRAIREAGVSEVSVGCYPERHPDSPSDEHDLEVLKRKIDAGATRA
VTQFFFDPDVFFRFRDRAVAAGISIPIIPGLMLQSNFAGLQRMAGLCGASVPGSLPPLYE
GLEDDAETRDLVTANVVAKLARKLEKGGAKHFHFYTLNRASLAICLVRLLGVRALSEAA
>A0A258EDZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus sp. 32-45-6|TrEMBL
MKITEHLKNAKSTLFSFEILPPLKGQSLKELLEGIEPLMEFKPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFHVDAVPHLLCGGFTKEETENALIDLNFIGVDNV
LALRGDAPKTEGKFIPERDGHCYASELVEQIVRMNQGKYLHEETENSFHTDFCVGVAGYP
EKHFEAPSMKFDLKYLKEKVDRGAEYIVTQMFFDNQKFFDYVKKVREAGIEVPIIPGIKP
ITTLAQITMLPRTFFLDLPDALTDELEKCKTNVDVKEVGIAWAIEQCRELIDAGVPSLHF
YTMSKADATYKIAKEIF
>A0A254S899|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWB4|TrEMBL
MKIIDILKQDKMSLSFEVFPPKKETSFENVKAATEAIAKLNPAFMSVTYGAGGGVSQYTL
EIAKNLKYNFNIPMLAHLTCISSTKETIHQRIEDMKAAGIKNVMALRGDLTPELIANGRG
DCDYHHAVELIRELKAADADFCIGAACYPEKHPESANQADDIKHLKEKVEAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPDAMKQAGIIYATDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKNFAG
>R6B6X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dialister sp. CAG:486|TrEMBL
MSTLKEKNQNHIFTITTELDPPKSASSAITEEQAQKVAPYVDAVNIADCPMAKMRMSPIA
LSCIIQQKYQVESIFHLTCRDRNVIGLQAELLGAAALGVHNILTLTGDPPKIGDHPNAKG
VFEIDSTGLIQIASCLNSGHDIEGHDLGAATDFYIGTTGNPGTDDLDAEIKRLEGKKKAG
AQFIQTQPIYDIKQAEDFLACAKDLDLPILFGIVPLKSFKMANYLNDKVPGITIPKKVLS
QMETGGRETGLAISKEIVTALREIHAAGAHLMPVNDIDAIPYIVGD
>N9LIX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 3929|TrEMBL
MTNRVPISFEFFPPKTDAGAEKLKTVHQELQRLNPEFFSITYGAGGSTRERTLAAIHDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A7Z7I6R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia arationis|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRASRAQLALLKPKFVSVTFGAGGSTQQGTLDTVLEMKQ
EGLEAAPHLSCIGSSKESLKAILGQYRENGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFNIEVAAYPEYHPQARTPKSDLENFVRKVQAGANSAITQYFYNGDAYFRFID
EARKLGVDVPIVPGVMPITNFTQLMRFSEMCGAEVPKWIARRLESYGDDREAIRNFGLDV
VTDLCRRLIDEGAPGLHFYTLNGAAATKTICERLNLKGV
>A0A7W8XPY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium paranaense|TrEMBL
MSSKTENGQRGIRISFEFFPPKSEEAETQLWNTVADLSEWEPDFVSVTYGAGGSTKAPTL
SAVRRMIHETPFTTASHLTCVGATREDTHRVIDDLLSTGVRRFVALRGDPPGGVGAAYQP
HPGGYANAAELVSALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGANRALTQF
FFDNDAFERYHDRVRAAGIKIPVVPGIMPIQNLTQLKRFAGACGTLIPSWLDERFDGLDE
DADKRADVAADVAAEQIEDLVRRGIHEFHLYTMNRSPLVSAVLDRLGIPRKTDARAGAAA
>A0A8C4S020|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erpetoichthys calabaricus|TrEMBL
MVNHVQLPDGAGHLSKCDSSGTSGSSGGESSKESSRCSTPVLDADRTDRLRDKMRRRIDC
GDKWFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIAST
ALNYCGLETILHITCCNQSKERITEHLKKAKRLGLKNLMALRGDPIGEEWEEEEGGFSYA
TDLVKHIRCEFEDYFDICVAGYPTGHPEAENYEQDLKHLKEKVDAGADFIITQLFFRPET
FLKFLKDCRAIGISCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIKGVIEPIKDNDAAIR
NYGIDQAVDMCKVLLGSGEVPGLHFYTLNREVATIEVLRKLGMWREDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKCPRE
ALLQMWGEELKNEQSVFEVFTNYISAKPNASGNKVTCLPWNDDPLAQETNLLKDQLEKVN
CRGVLTINSQPNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSNENVTALLKVLKKYEPR
VNYHIVDVKGKNITNAPDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQW
AKLYEEESPSRMIIQYMHDNYYLVNLVDNDFPLENCLWQVIEDMFDLVNSTVEHAI
>I3XA93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium fredii (strain USDA 257)|TrEMBL
MSPDINPLDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYSPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRRPWKHEATPAETLVAERLEHLREGIEENQQQMAEAAAH
HPH
>A0A7Z0DJ23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides panzhihuensis|TrEMBL
MVTGRGRSLAELINEGDRSFSFEFFPPKDEAGEEQLWNAIRALEPYRPTFVSVTYGAGGS
TRDKTVAITGRIAAETELLPVAHLTCVGHTRDEVAAILDSYAAQGVTHVMALRGDPADGP
RAEWTPTAGGLDYAIDVVRLARERGDFRIGVAAFPEGHPSAESIEADADVLVAKAEAGAE
FAVTQMFFRAADYFGLVDRVRARDVDIPILPGIMPILNLAAIRRQSELIGAEVPEEIVER
LTAAGPEPADIRAEGIAVAAELCQELLDGGAPGLHFYTLNRSRATLEIFAKLNVTP
>A0A2H5WQ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR14|TrEMBL
MVRERKEEELPLAEPSRLSQILGKERVIAVELDLPRGLKVQKVIEGARLLKEHGVHVIDI
SDGARARLRMNVIAISHLVQREAGIEVMMHFACRDRNLLAIQADLLGAHALGIRNVLAIT
GDPAQIGDYPTATSVFDVDAIGLVRILRRFNEGRDLAGNTIGVRANFTIAVAYNPLAPDP
ETERDRLRKKIEEGAHLVYTQPIFEMRVVEETAELMNRLGVPWLVGVLPLRSARHAEFMH
NEVPGVSIPEPILRRMAEAPEEDALAVGLEIARRFVAEAAPYAQGVYLMPPAGSAQIALQ
VIEAIR
>A0A1Q5S9H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. NAS80.1|TrEMBL
MTDLTTPAQADGQDGHHAVKRPAISFEFFPPKTEEMERNLWETINRLAPLEPKFVSVTYG
AGGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDP
PGGIGTPYSSHPDGYQSSAELVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLQAKV
DAGATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRAGTTVPD
WFAAKFEGLDDDAETRKLVAAAVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIR
AKSAQKAA
>A0A1F3D143|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWA2_40_15|TrEMBL
MEKKLKSGEFVVATEVTPPLGASTGSLKRDIESVRPFVAAINFTDSSYARPRMSSIACSK
IAVDLGAEPVLQITSRDTTRSGLQGDVIGINGLGIYNVLCISGDSPRVGPTPTGSMNFVD
LDSVQMLWILRRMRDEGTYLDGRKMKENPKLFLGAATSPFASDPELQAIKDTKKVNAGAQ
FFQTNLIFEPDRIDPWLEQLYRRNILDKVYILIGLAPLKSYKVAQYLHTKVPGVSLPAHI
LNRMEKAGESAPEEGVQIALELIDGIKKKHGVHGIHIMTLGWESIVERIVTESGLLP
>A0A0U0W8E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium bohemicum DSM 44277|TrEMBL
MEFGPCGGVRHDGQCEMRPGPCSFGDVVPWSGDPVEPRAPRPVRAPLVLADFSCTPFDRG
AVAATASVLAPGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDRNRVVLEQE
LRGLKAIGVDTALCVTGDGRGYDVRPEVTQTFDLDGPRLVSLAAALDMVPAVPETPTAPP
VHARPARLVEKQRAGAGVAVLNHVPSPDVVAEFTKAARSLGLVIPVIAAVAVFTDSVSAA
VLEGLPGVGLDGELIERVLGAADPVAAGIAAAVDEARTLLSIDGVDGVNISGLASASGAR
VGAEIKAEVGRRVRKEAS
>A0A0C3B3U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serendipita vermifera MAFF 305830|TrEMBL
MRITEKIERAEKENRTWWSFEYFPPRTAQGLQNLVDRIERMRKLGPEFIDITWNAGGRTS
DLTSELVKTCQSLIGIETCMHLTCTNMPKEKVDVALREAKMHGCRNILALRGDPPQGQDE
WTATQDGFVHGIDLVKHIRKHYGDYFEIAVAGFPEHQMLPEEELQTELAYLKQKIDAGVS
FIFTQMFYDLDLFIKWVHNVRKAGITVPIIPGINPIQTWNGFMKATSLAKITIPRSFLDV
LEPHKNNDEKVRELGTRLVADLCHGILNAGLGIRGLHFYTMNLEKGTRMLLEELKFLPRV
ETIKPLPWRQSLTPNRRAETIRPIFWANRTKSYLSRTENWDEYPNGRYGDASSPAYGELD
GWGISIKHTEEEAQKLWGYPETKEDIGRLFATFCRGKLAALPWSDEAPAAETSVISEHLS
RLNELGFFTINSQPAVNGVRSNDSMHGWGPSNGFVYQKAYLEFFVSPELLAALIPQIERD
PMITYYAINKRGDLRTNTKSEGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGMQ
WSRVYGNGTPSQKLIADIMNTYTLVNVVHNDFRAPEAIFAPFYRAAQATPPSVNGQVNGH
KETNGIAESAPLTNGLTNGHA
>A0A263DY84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. MH-G8|TrEMBL
MGVDADRFKVVCEIEPPTRPDLTHARHQIGVLTPIADSFLIPDNHIGRATVSSIAVANEV
RAMGGQSVACVNSRDRNLLGFRRDLLTAAAYGVDRFLFVHGDKPTAGGRTSELTVRTMIE
EARGATGQPAFAGIAPFRVGVTAGHHRRLPAWKQDADFVFLQVGYSVDAFLRWREKNPTD
LPVYAGVMVLASAGMARRLRTSIPDIEIPDALVEDVAADPGAGVDAACRQILDLRDTGAF
AGVHLVPVSRYREVSARLERAMSD
>A0A2H6FS11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Abin10|TrEMBL
MIKKITDIFKEKDRTFSFEFFPPKTPKGIENLYRAAEELNRLGPDFVSVTYGAGGSTRGA
TMDICVEIQKRFDITVMHHLTCVGHSRQELEAVISQLKDNNIKNILALRGDPPKDVENQE
PAPDGLEYCYQLNDLIREHSKDFFSIGVAGFPEGHIHCPDKDTDTKYLKIKIEHGGEFVI
TQLFFDNNIYSEYVERLGKQGVNIRVLPGILPITSYEGLLKFCDICGATVSQEVHDIFKP
LNGNEELTRKAGIEFAVKQCRDLLERGAPGLHFFTLNKVEPTKEIWNRLGL
>A0A0J5IUA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus khoisanae|TrEMBL
MSFFHANQREALNQNLAELDGQIRVSFEFFPPSTPEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKEKTGLDAAPHLTCIDASREELRDIAHDYWRNGIRHIVALRGD
LPNDSGKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATITNVRIPSWMTRMFE
GLEDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPS
>A0A560V4H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. SJZ115|TrEMBL
MKPIELSLEFFPPKTAEGADKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLSAAPHLSCIGSSKDNLRAILDQYRSHGIRQIVALRGDLPSGMGEVGELRYACDLVRF
IRAEHGDWFHLEVAAYPEYHPQSRSPKQDLQHFADKVKAGANSAITQYFFNADAYFRFVD
DAARLGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGADV
ITAMCDRLIKQGVPGLHFYTLNLATPTRVVCERLGLSG
>A0A1H1L3L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopseudomonas xinjiangensis|TrEMBL
MSTTNPQAVSFEFFPTKTDAGHEKLMAVADVLAQESPEFFSVTYGAGGSTRDRTRNTVLQ
LDQEVKVPTAPHLSCVGDSKEDLRSLLNEYREAGIKRIVALRGDLPSGMGQASGELRYAN
ELVEFIRQETGDHFIIEVAAYPEAHPQARHFEADLEHFVRKARSGADSAITQYFFNADCY
FYFVERVRKAGVEIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIAA
FGTDVITDMCQQLIKGGAPALHFYTLNQAEPSLAVWRNLRTS
>A0A1L5F864|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium kluyveri|TrEMBL
MNIKEKPLIFDGAMGTYYPHISKNPLPKCELANIYDRNTILKIHREYIGAGCMAIKTNTF
GANKVSLESDFNRVREVIVNGYEIAKEAAKDTDVLVFADIGPIPFLESMDLYEGYKEIVD
LFLELGAKYFIFETFSSDEYLKEISEYIKGKDPEAYILVEFAVSPEGYTRVGKSGKKLIE
NILKIPTIDACGFNCFSGPYHLLQYIKTFNIGNETISVMPNSGYPTVIDNRTFFDNTKEY
FAQRMLEIAKQGVSILGGCCGTTPEFIRETVIKLKKLSKSEIVLKKQAEKIHTEKPVVKN
VLLEKINKGKKIIAVELDPPIDTEVDFFLNSARTLKEQEIDAITIADCPIARARVDSSLL
ACKLKRELDITTIPHMTCRDRNINATKALLLGLNIEGVNNVLVVTGDPIPSAERDEVKAM
FSFNSAILANYITNLNDTIFSSPFNICGALNVNSRNFNTELKRAKTKIENGIAMFLTQPI
LTEEALENLKLARRELPARILGGIIPVVSYRNACFMNNEISGIRVSEEIIKQYKDISKEE
AAKLAVKISTDIAEQIYPYVDGYYLIMPFKRIDIISEIIYNIKVKNTITI
>A0A7W7GWU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes octamycinicus|TrEMBL
MSLGLESKLPSTPSIGELIRGAAPTFSFEFFPPKTPDGERLLWQAIRELESLRPSFVSIT
YGAGGTTRETTVAVTERVATETTLLPLAHLTAVDHSVADLRNVIGRLAGAGIRNVLALRG
DPPGDPMGEWVRHPEGVDYAADLVRLIRESGDFSVGVAAFPFKHPRSADVEDDTRNFVGK
CRAGADYAITQMFFDAEDYLRLRDRVAAQGCGTPIVAGVMPVTRMATIERAGQLSGAPFP
PALRREFERLAGDDAAVRELGIEKCAEMCARLLDEGVPGIHFITMNRSTATREVWQRLAP
ADVAAAA
>T5AGT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243)|TrEMBL
MDRITDKIAALPDGAEYFSLEFFPPKTAMGFSNLRHRMQRMEQALRPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRRVLDKALEDAKALGIRNILALRGDAPRKEE
YRDADADADDDELTSAVDLVCYIRRNHGDYFCIGVAAYPEGHADESHPVGQSLDHDLPYL
VEKVQAGADFIMTQLFFDIDAYERFEKTLREHPSGAFTSIPIMPGLMPIQGYQMIKRTTK
LSHARMPESIMARLNAVRGDDERVKMVGVDVISEMVEQIRAIKTGDSGHRGFHFYTLNLE
KAVSLIVEKTGLMQQDSSDSDEAVVDDVPLSPLPIIQLNGNAPLRPSSHSRTSRRHSSVG
SDPHNREAGVPAGGINSRANTLAISEGEGALGREATWDDFPNGRFGDARSPAYGEIDGYG
VSLHMSVTQAVRLWGYPATRRDLDDIFVKHMQGQLAAIPWSEEELMGESSTIKPCLIELN
SKSWWTVASQPAINGAPSSDPTFGWGPVNGFVFQKSFVEFFLPSDDWKALHERLSSPEVR
ESICFYATNSVGDFASSDSSGGLNSASSWTSTNAVTWGVFPGKEIVTPTIIEEVSFRAWS
EEAFGIWGEWAKVYGRGSDSETLLNGIRDDVWLGNIIHHDFVDTNALWKLLLE
>A0A355UUV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKIKNMFSENKTVFSFEIFPPKKDSPVDTIYNTLEQLHDLTPDFISVTYGAGGSAAGAST
CEIASVIKNKYNIEPVAHLPCINFTKAEITDILNDFKNNGIENILALRGDINPDIPPKKD
FRYASELIQFIKQNGDFDISGACYPECHIEAENIIEDIKNLKNKVDCGADHLISQLFFDN
EIFYSFEEKASIAGINVPIEAGIMPVVNKKQIERMVSLCGASLPSKFTKIMQKYENHPEA
LRDAGIAYAVDQIVDLITHGVDGIHLYTMNNPYVARKISDSVSGLLNV
>A0A1E9TFA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC072B03|TrEMBL
MTTVHPALSFELFPPRSHASCESLIRTIAELEGTNPDYVSVTYSGDAKRRQKTLALLDYL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDVQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSARLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMSVPADLAYALETATSSAE
LHRIGVDYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEF
A
>A0A3D2HVH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKINNIFNKSDRAILSFEVFPPKKTSPIESVYSKLEEICALKPDFISVTYGAGGTGGHSR
TCEIASKIKNDFGAESVAHLTCVNSTKADIDSTLEDFKAHNIENILALRGDYVDGVEPKK
DFIYASDLCEYIKSHSDFDLGGACYPEVHLEAKDEVEDILNLRKKVEAGAEHLISQLFFD
NSVFYRFLERAKIAGINVPIEAGIMPVTNKSQIERMVSMCGASLPSKFVKIMQKYDSKPD
ALRDAGIAYAVEQIVDLLANGVDGIHLYTMNNPYVARKISEAVVSLL
>A0A0R2BBL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schleiferilactobacillus collinoides DSM 20515 = JCM 1123|TrEMBL
MISFEIFPPRAKASEKATNRFYASLDTLASLEPAYISVTYGAGGSNDHASTLALCRYIKV
HYGIGAVAHIPAVAFNAQSLKTYLADLKQAHVENVLALRGDLPADGRPNNDFPFASDLVA
AIKRESDLNILGACYPDVHPEAENCVVDVQHLKEKVDAGASQLISQLFFENEHYFSFLER
CELAGIKVPIQAGIMSVINERQIAKMATIGGVELPPKFLKMMHHYQDNKIAMRDAGIAYA
VDQIVDLLSEGVDGIHLYTMDNPVVTQRICSAIKTLI
>A0A2S7D924|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas pisi|TrEMBL
MTHLSFEFYPPKNDDQRAQLERTATRLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSREEIRELLKLYRTIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAVDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ASLCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A5C2AXH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cholerae|TrEMBL
MGYTHAGHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQNIVALRGDI
PAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVAAGIGVEIVPGILPVSNFKQASRFAAQNNVKVPNWMVKQFEG
LEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A192INS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium NRL2|TrEMBL
MEARPMTEMFRLGGSPRIGASIEATPTQVLDKVDLAGLFPVNTRVYLTDLGTDDSARLIR
AARLLQDYGYVAVPHLAARRFPSWAAFEARVRALAGEAGVTEALAVAGSPERQAGPIAAS
IELLRSGWFDRLGFTRIGVAGHPEGSPDIAPEALDAALREKNAFAAETDAELYLVTQFGF
DARRFIAWAERVSAAGNRLPIHIGVSGPAKIATLLKYAAACGVGESLGFLKKRAGAVTAL
ATGHSPESVVQPLENYWAADPAGPIRQMHVFPFGGLKKSSQWLFERGSWVNGIEAFADTQ
PIQLEARK
>A0A1Q7RJV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_40CM_2_68_5|TrEMBL
MNRPAPVFRLAEALRSGLPVVTCEIASGDGADAGDIVRRAHLVRDHVDAVNVPDNTAGIV
HLSPLAASALLVREGVDPVMHVTCRDRNRLALQSDLLGAATLGVRNVLCLTGDHMVHGDH
PDAKPVFDLDSLQLLVLANLLRGGRYMSGREIVPAPDLFPGATENPFAPPYDFRPLRLMK
KIEAGARFIQTQITFNVARFAAFMEGVRDLGLDRRVPILAGVAPLRSARAARYLQERVPG
MEVPDAIVRRMEQAGPDRTRREDEGIRICVEIIEQLRDIKGLAGFHLMPIRWEEAVGEIA
SRARLLPARASLLGPFAAAAVDDGGAEGRAAADGAALQHSREHRA
>A0A7Z8BFI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella sonnei|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5N9DTG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MTKFTEYISNKSGSVTFICDFSPPKGLDLDELNKVSSLNSDFIYVAYNPGKSVRINSLQT
AHWIKQNSSSDVVFAMGCRDMNKLAIQSHLLGAQLLGLENLLIFQGDPFTPAESINVKTV
MDYKSTELIDSVNMMNNKLDYKGKELSKPTDFCIGSTIDLNKDLDNEVRLTNQKVKLGAN
YFLLQPIFSIDILNKFLETYNKISKSNLNIPLCIGVQILNKTTKSFGKIPTKIKHQLESG
KSPIMITSDFIEELLSNNFNNIYLLPSLLPDGKRGYEQASRIIKEFK
>A0A3P3FTL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium tamadayense|TrEMBL
MRLRDENHAGIDLQYDPPPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYYRAKVF
DGWVDAINAVDASGANCHVSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAAMG
IANILCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRIMRDNGKFLSGRKLTTPPQIFLGA
AINPFAPPYDFRPYRLGKKIAAGAQFAQSQYCFDVPMFRTYMQRVRDLGYTEQCFILCGV
GPLASANTARWMRNNVPGVHIPDAVIKRLEGAADQKKEGKQLCIDIINEVKEVEGVSGIH
VMAYRQEEYVAQIVHESGVLKGRRPWTRELRADDRIVAERLDHLMQA
>J2XVQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens Q2-87|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKVPAAPHLSCVGDSKEDLRSLLTQYKAAGINRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGEHFHIEVAAYPEMHPQARNFEDDLLNFVRKAKAGANSAITQYFFNADSYFY
FVERIRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>V5Z3M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia piriflorinigrans CFBP 5888|TrEMBL
MSFFHASQREALNQSLAEIGGQINVSFEFFPPRTGEMEDILRNSIDRLSSLKPKFVSVTY
GANSGERDRTHTIIKGIKERTGLEAAPHLTCVDATRSELRTIAEDYWNNGIRHIVALRGD
LPPGGGRPEMYAADLVALLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMTSMFA
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPSPALAL
AAS
>A0A3N2KUA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muribaculaceae bacterium Isolate-080|TrEMBL
MRVIDHLRSNPGSTAFSFEILPPLKGNSILKVYNIIDKLREFEPKYINITSHRSEMIFKE
MPDGSFRPQKMRKRPGSVAIASAIQNKYGITAVPHIICKGFTREETEYALIDLNFLGVHD
LLLLRGDTKGPEKSDDPAKINLHATDLQQQVNNFNLGIYADGERFEANETPFSYGMACYP
EKHEEAPNMESDIYYAKQKVDAGADYLVTQMFFDNEKYYAYVERCRKAGITVPIIPGIKP
IVFKNQLNVLPKIFRSEIPEPLAAELRGCESDAQVKEVGIEWCIAQCHDLMANGVPSLHF
YTLMASDSVRRIAQAIY
>A0A7S3DCU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Palpitomonas bilix|TrEMBL
MKYFLSKQYSNAKKLHTIIEVFKPATREGENSLMERLNRLATLNPALFSISSQNHQHENN
TLSLTQLVREDVCAEVQVHLQCDEPLEILRANIASAKAFNVRHFLFFVLRQPQALVQEGG
EVSHDSVAIEEALKKMRQLLHLLGEEQSIGVMVPYCDTRDEQIWASVARLACPGIDYVVL
PMIATTQSYSARCNLLTKHGVRCPIVPAIVAAALNARSLESLINSTTAGRDEEWQCIVRQ
LLEIEEQIVLSGRTHRLNVHASEQGRDSSSLSAQKSEERASSTLRSFHSTTIHRIKKQKA
EAIQAFWLSRCVELVEGIQECGSPGVYLVSLNLESVVKKVAEACGLREGGTLPWRPRLEA
GQGEQIRPIHWANNPKRLDILFSHF
>A0A7G6E4V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermanaerosceptrum fracticalcis|TrEMBL
MLIKDIFATKKPVISFEIFPPKKDSPIETIYNTIEGLKDLKPDFISVTYGAGGSTTNRTV
EIASLIKHKYGLEALAHLTCIAATKQEIEGILNSLKDNGIENILALRGDLPQDPDFKFPD
PLHYQYAKDLILHIQSLGSFSVGAACYPEGHLECDDIEKDLSYLKQKVDTGVDFLITQLF
FDNEIFYEFLDHMARARINVPVTAGIMPVLNRKQIERITSLCKASLTKKFIRIMERYEHN
PEALKEAGIAYATEQIIDLLSWGVDGIHIYTMNRPEVTRKIVENMSTIRSVIST
>A0A8J5C7N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MSLVCSLHLPLFWSKLGPAACVPMQVAPTSSSTRATMQSSSPSLGRKLPLHRLALEEGSL
NLFPYIAARTSSSHCWEEAKRTAAGSRSLCSSRHPMKKKLNVQLFAKVTSIKVLDFEFPV
VCMETIMHLTCMNMPVEKIDHALNTIKANGIQKVLALKGDPPHGQDKFVQVASGFACALD
LHIRAKYGDYFGITVAGYPKAHPDMIQGDEGATLEAYNSDLAYLKRKVKSWSTIREA
>A0A8J5HT32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MKVVDKVRSAAEGNGRTVFSFEFFPPKTEEGVENLFERLDRMVAHNPSFCDITWGAGGST
ADVTLDIANRMQNMACVETMMHLTCTNMPVEKINHALNTIKANGIQNVLALRGDPPHGQD
KFVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDMIQGDEGAPLEAYNSDLAYL
KRKVDAGADLVITQLFYDTDTFLKFVDDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPPEITAALDPIKDNEEAVRAYGIHLGTEMCKKILDHGIKTLHLYTLNMEKSALAILMV
NLGLIEESKISRSLPWRRPTNIFRSKEDVRPIFWANRPKSYISRTVGWDQYPHGRWGDSK
NPSYGALTDYQFMRPRARGKKLHEEWATPLKSVDDVNERFMKFCQGKIRSSPWSELDGLQ
PETKIIDEQLSQVNLRGFLTINSQPAINGEKSDSPAVGWGGPGGYVYQKAYLEFFCSKDK
LIAITEKCKALPSITYVAVSKEGECISNCTLNAVNAVTWGVFPGKEIIQPTVVDPASFMI
WKDEAFEIWTRGWACLFPEDDPSREVLTQVQKSYFLVSLVDNDYVHGDLFAAFKDL
>A0A8J5F1M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MRFETGHVLGVLVASSPLLEQAWTRCLRANAGSASFVIDKSDDAVFIAFSRAQAAASPSG
LGRGFFEHVSLYSSTHKLFALLGRGEEDSGGKPQPVLLQVGALRLFMSLHPMKKKLNVQL
FAKATRCLRLPQKTYMDTLTFGAPRCDYCDSIKGLHGNYYALNMHEYACGEDRPCSDTIK
ANGIQNVLALKGDPPHGQDKFVQVAGGFACALDLVQHIRAKYGDYFGITVVGIQVNLEQS
QSKCKYGDYFGITIVEAHPDMIQGDEGATLEAYNSDLAYLKRKVDNS
>A0A089KCC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL R7-0273|TrEMBL
MKPDLRSAWKNNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYIEAGAVL
LESNTYSANYDKLAKFGLEGKVEEINRAGVRIARKAAGETGYVVGAVGSIRAGKRANLSA
AELKRFYAQQLSALLDEQPDGIMLETFYDVEELHLALKAVRKLSGLPVICQLAVDETART
LDGLTLPEAFRILEQDGADVIGFNCRTGPNGIKRALRTLQGSLALPVSVYPNAGIADYVD
GQYRYGATPDYFGQMAPVFADMGSRIIGGCCGTTPQHIAEISAALQGYIAQPLAERAVTR
STEQIVVHEHLDDSGDQNGREPNLVDLVKERHTVIVELDPPRDLDITKFMKGAEALRRAG
ADALTLADNSLAVTRMSNMALGSLVQARTGLRPLVHVACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIRQLNDGIAFSGKPLKQKAKFVIGAAFN
PNVKHLDKAVQRLEKKIASGADYIMTQPVYDPELIANIAAATRHLDIPIFIGVMPLASGR
NAEYLHNEVPGIQLSDEVRRRMQGLEGEAGRAEGVAIAKELLDAATAHFNGIYLMTPFMF
YEMSVQLLEYIWEKQGRKLSPLFR
>S6CGS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|endosymbiont of unidentified scaly snail isolate Monju|TrEMBL
MNPDKTFSFELFPPKTEKGMVKLQSTVARLAERRPAFFSCTYGAGGSTRDRTFATVDWLV
SQGIDTAPHLTCIGNSIAETLEILNRYREQGIRRIVALRGDPPSGTGLGGGELTHASELV
ALIREHFGDHFHIEVAAYPEMHPQAPNFLVDLDNFRTKVEAGADSAMTQYFYNADAYVHF
VEQIRARGVDIPIVPGIMPITNYSSLARFSDACGAEIPRWIRKRLEAYGDDVESIRAFGL
EVVTGLCEQLLAAGAPGLHFYTMNQADPTLAIWDRLGL
>A0A1R4FBB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter rhombi|TrEMBL
MPSPTDSPHPLGAELVRGFSLEMTGKDQRSLAEAAGTIPAGTRVNVTFLGNEDAGLRVAA
AAAVRAAGHEPVPHISARRLASFGELDGFLDQLVTQARVTEVFAVGGDPVEPLGPFPDAL
ALIASGRLQAHGVTGVAIAGYPEGHPEIDDASLWAALQDKASAVRSAGLSGSIITQFGFD
TRPVLSWLAELRGRGIDLPVRIGVPGPAGIKRLLSYARRFGISSSAGIAQQYGFSLANLL
GTAGPDRFVNDLAAGLDHRLHGEVRLHFYTFGGLSATARWAQDFRAGP
>A0A3Q9D5K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas poae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTQYEQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEEDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCESLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1H8PWZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinihabitans flavidus|TrEMBL
MIDRIRASQTKDALLQDLYEMRGRIPLSFEVFPPKSSDLCMALHHTVDQLAPLAGRGFSV
TMSSGGATRDRTVDTAAAIATRTGRPVMAHLVSLGLSRDAVLNTADDLWARGIRRILALR
GDRPKGESGGLPPGFDHASELVEALRTRHDFEIAVAAHPETHPEAETLDQDIGYLKRKLD
AGAGSAFCQFVLDPATYSRFLEDCGQHGVDEPIVPGLMPLERWPRLKRFARMNGAMVPDW
LPTFRPRRDHART
>A0A3C0XBD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp|TrEMBL
MTAISFEFYPPKTDEQRGQLDRAAARLKDYAPDYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIAFI
RAEHGDAFHIEVGAYPETHPQASDALADLRHFKAKIDAGADAAITQYFFNADAYFHFVDA
VRKLGVTVPIVPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGAEVV
AGLCQRLVDGGAPGLHFYTLNLAKPTVSVLKLLQG
>A0A1X1Q942|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerovibrio sp. JC8|TrEMBL
MGRISVELIPRSEEGLRDDLQIVKDNAPGVELINIPDLLRFDMRSWQGAAIAQEYFPAVM
PHIRAIDVDLTQPLSMRPELRQSGITEVLVIEGDPPQDMSHKFYPTVTTDVISKFHQEMP
EVKVYAGIDQYRGSMRQELYRIQRKLQAGAVGFFTQPFFDIRFMEMYADMLEGQNVYWGV
SPVMSERSQSYWELKNNVIFPKGFQPTLEWSIEFSRKALQFAKERDANLYLMPIKSNLEA
YLQGVLG
>A0A1H0JE59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas poae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASFNPDFFSCTYGAGGSTRDRTINTVLQLE
NEIKVPAAPHLSCVGDSKADLRGLLTQYKAAGIRRIVALRGDLPSGMGMASGELRYANEL
VSFIREESGDHFHIEVAAYPEMHPQARNFEHDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQTEPSLAIWNNLKLPR
>A0A420WL32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litorimonas taeanensis|TrEMBL
MNTILPKRDPNAAIGAIARAATSSAKAAPTGDIRVSYEFFPPKSDKMEARLWDAIKKLEP
LNPDFVSVTYGAGGSTRERTHNAVSRMVKETTFEPAAHLTCVGSSRDEIDEIVMDYWDAG
VRHIVALRGDPQDGIDAKYKPTENGYAYSCDLVAGIKSIADFDVTVGAYPELHPESGDWR
EEIDNLKRKVDAGATRAITQFFFSPDVFWRFQDRVLDAGIDIPIIPGLMLQPNFKGLARM
SKLCGVSVPEWYAELFEGLENDTQARELLTASLAAELTAELHDRGVRDFHLYTLNRAEMA
VAVSRILGLHHRKGGRTPNRHSA
>A0A5D0GG98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Formosa maritima|TrEMBL
MKVTEHIKKANGNTQFSFEILPPLKGQHIQSVFDSIDPLMEFKPPFIDVTYHREEYVYKE
LENGLLQKKVVKKRPGTVGICAAIQNKYHVDAIPHILCGGFTREDTENFLIDLDFLGINN
VMALRGDAVKTETYFRAEKEGHNYASELVTQISELNSGSYLDEELLNTSATNFCVGVAAY
PEKHMEAPSLDSDIHFLKKKIKNGAEYIVTQMFFDNQKFFDFVKKCRKEGITVPIIPGLK
PIATKKQLNLIPHRFHVDLPEELILEVVKCKDNNQVRQLGIEWCIEQSKELQKAGIPVLH
YYSMGKSDNIKAIASQVF
>A0A1Q7UG92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_1_20CM_4_69_9|TrEMBL
MCRASSEGDEVPAQNRFLERLQSGPAIVGDGGMGALLSAAVPRLRSPEEANLRAPEAVVS
LHVSFINAGAELIETNTFGANRRKLAHNFLEDELEAINSAGVKLAREAREVTGRDVFIAG
SIGPLGEPAVSRVRRELFAEVAAVLDGRGVDLFMVETFYDLDEAVDAIEAVRGVSSLPIV
ALLTFDESAETLAGITATEAAERLSGLDVAALGANHGAGLLAALAALERMAKNGKPLAAL
PNVGLASLAGGRVIYPHATPEYFAEFAAHARDLGAMVIGGCCGTTPAEISAIRSAVEQER
KPRAPLVFESPELVVALGEEQRETGLSRAFANGEWVVSVQLDPPLGGNSAGLVEVAAALK
ESGLVAWVDINDNATARAGMSSLMVSAAIERQAGIETIPHLTTRDWSVMGLESMLLGAHA
EGVRNIFACTGDPPEVGDYPGSRGVYEIDSIGLTRLMTNLNRGEDFNGRPIDAPTSFFGG
VAVNPTADDLDLELERFEQKVEAGAKFAITQIVFDIERFDAFTERLGGKWPIPVLIEAFP
VTSHRLALRLHNELPGIVVPDKLQEDLQNAGSDAADVGFAHAREIIAAARERAAGVCLVA
PFRRPLRVLELL
>A0A7C1ZH38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp|TrEMBL
MTNKLTISCEFFPPKTDKGIATMREVREQLSPLKPEFYSVTFGAGGSTQDNTLDAVVEIQ
QTHAITNIDAAPHLSCVGSTAERIRDMLNTYQSHGIKRLVALRGDLPSGMRDPGDFRYAN
ELVEFIRQETGDYFTIEVAAYPEVHPQADSAHADFINFKRKVDAGANSALTQYFYNIDSY
LYFLDRCQKNGIEIPIIPGIMPINNFSQLARFSDGCGAEIPRWLRKRLEEFHDDTDSLQA
FTLDFLTDFTEKLINVGVPGLHFYTMNRTEPTLTICQRLGLID
>A0A8B8P0Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodamnia argentea|TrEMBL
MKVVDKIREAVVACERGGEANSGRNRREAVFSLEFFTPRKASEVDHLLGLIGRLVARGPA
FCDLTWRSGSLATDDLTLEVTAKMQNAVPVETMMHLACTNMPVQRIDRALERIKSDGVQN
VLALRGDPPNGQDKFVPVPDGFASALELVEHIKAKYGDYFGITVAGYPEGHPDVIGSEGV
ASDDAYQNELAYLKRKVDAGADLIITQLFFDTDIFLKFVNNCRQVGITCPIVPGIMPIAT
YKGFVRMTGICKTKIPAEVSAALEPIKHNDEAVRNYGIHLGTEMCKKILASGIKTLHMYT
FNKEVSALAILMNLGLIEESGVSRSLPQRHPSKVLPVEEDQHPNSGTKEAKKKF
>A0A3A9IH59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerotruncus sp. 1XD22-93|TrEMBL
MRHAFQAPLWFDGAFGTYYFSLTGDETPCELANLKNPALVGQIHREYLKAGATALKTNTF
AANPGTLPDPEQLGTVLQAGLEIAQKAAAEHGAEVFADIGGISAADAEQFYLTVAERFLD
LGVTSFLFETLPSYEELVPALKRIREREPEAKIVVSFAVSQDGYTRRGLSHRALAGIAAA
DGYADAVGFNCVCGPSHMVSLVKSLGEIGCPIIAMPNAGYPSSLNGRVIFEDNAGYFATR
MVELYQAGVDLLGGCCGTTPRHIAQAVRAVCSVTRPERLTAVSEKTVASQVLPHGGKGKK
VIAVELAPPQDCDCSFLLSAAGELKSCGADMITVSDSPLSRARADSLMIAAKIRREVGIE
VLPHLCCRDKNHIALKAGILGAALEGINRVLVITGDPPVQSNMRNPGVFSFNSFDLISFI
ASMNTDLFSGRPFLIGGALNVNAANFPVELERARKKIARGAGMLFSQPIFSEQAVKNFLL
ASRELDCALFAGILPVAGYRNALFLVNEVSGIEIPDAVMQSLKDKTPAQAAEISIAYSAG
ILEQVYDAADGFYIMTPLKRVDIVRGLIERIHRREEQEESK
>A0A554U5S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. KBS0706|TrEMBL
MTIFPANASAEARRDPIVSFEFFPPKSEAAEATLMETVTRLAPLAPDFVSVTYGAGGTTR
DRTFGIVTKIQDGSGLPTASHLTCVGASREEIDDVARALWAAGIRRIVALRGDPPGGAPY
EVRPDGYAYAADLVAGLRRIADFDISVAAYPETHPAAPSADFDLDNLKRKADAGADRALT
QFFFDTEAFLRFRDRSAAAGIGLPIVPGILPITNFARTKEFATACGAAVPDWLEMLFEGL
DETPDTRQLVAASVAVEQCRQLQTHGVEEFHFYTLNRAELTLAICRFLGIRPRRAEACAA
>A0A2S0LQM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. oral taxon 897|TrEMBL
MTSPAPTRPTLSLELFPPRSSAAWGRIDRLLATAPDFVSVTYRPRFLAPGGAGEGADAAP
ARPDPAPADPVPCVRVVRERNAAEDVAAHVISSSQVPLMAHLTCIGYTRRDTVEIVSHFL
AMGVRRFLALRGDPPTGFSPQDVHGELRYATDLVQVIREVEASYFGDGQRHVTIAVAAYP
AAADHLREVEVLAAKQAAGADLAITQVFYEPEDYVALVRACTYAGVTIPVLPGVIPLTDL
TRLTRLESLTGVAVPRRLRDSLSTATGASLVARGVDATLGLSTALLEAGAPGLHLYTFNR
TRPALDIISHLRLGRILDGAAPDREVRDAVDRGYLQATPGRGPSFLRRGGRAAAGAPLQP
AQPHTTKTTIKENA
>A0A519Q171|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MAANLAEARALLLSPLGPVARAGSNHNPVRVSFEFFPPKTDEAEANLWKAIRRLEPLNPA
FVSVTYGAGGSTRERTHRTVTRILAETTLKPAAHLTCVEASRDEVDQVIDSYKAAGVDHI
VALRGDPPGGAGIGGVYEPRADGYANATELTQAIGRAGGFDITVGAYPEKHPESPSLDHD
IDVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLARMCG
ACGASIPDWLRAHFEGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRADLVYA
ICRVLGVRETAQ
>A0A3D5ZZR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanicaulis sp|TrEMBL
MRGGTMPDGRTLPVRPGPAISFEFFPPKNEAMEERLWDSISRLAPLDPLYVSVTYGAGGS
TRDRTHRTVRRIVEETALKPAAHLTCVDARCDEVDEVIRDYWNAGVRHIVALRGDPPGGV
GERYEPFEGGYANAAELTAGIRKLGDFEVSVGCYPEKHPESASFDHDIDLLKAKIDNGAT
RAITQFFFDADIYFRYVDRVRKAGIDIPIVPGIMMQANFEGLVRMAGLCGATIPARLFDL
FDGLESDPGTRELLTANVVADLCHDLSDQGVDQFHFYTLNRAELALATCRLLGVRPVEMA
A
>A0A4Y8CEK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. CH185|TrEMBL
SKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISFIKKQEYFEIYAACY
PEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNCALAGIDIPIYAGIM
PITNKRQVLKISQLCGSKIPPKFVKILEKYENNTLALEDAGIAYACDQIVDLITSGVDGI
HLYTMNKPKAAIKIYEAVKHLLKEELHA
>A0A0K8QW47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium 6E|TrEMBL
MLRNPLRETKRMKVTDIIRKSGKTIFSFELLPPLKGNDASRIYRTIESLLDFNPAYINIT
THRDEIEYKEQPDGTITRKITRKRPGTVAIAAAIQHKYNIPVVPHILCGGFTKSETEHVL
IDLNFMGIRNVLALRGDGRKGDSVFRPEPEGHAHANELVEQMVNLRNGKYLDPDLKNNHP
LDFCIGVAGYPEKHMEAPNPETDLLYLKQKVDAGADYIVTQMFFDNAVYFSFVEKCRQMG
ITVPIIPGIKPIALKNQVTVLPKIFSIDIPVELAKALTACRNDEEAKRVGTEWAIHQSKE
LVAAGVPSLHIYTYGISDNVGDIVKAAF
>M8D7D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus flavithermus AK1|TrEMBL
MGLLDDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIDAGAEVIQTN
TYGANYVKLARYGLQDDVKQINEAAVRLAKQAAQGRAYVLGTIGGLRSTNKSTISLEEVK
RTFREQLYALLNEGVDGLLLETYYDFEELQTVLSIARKETTLPLIAHVTLHDIGVLQHGI
SLADALHQLEQLGADVVGLNCHLGPYHMLRSLEEVPIPTRAFLSVYPNASLPQYRDGRFV
YETSEQYFEETARAFRDQGVRLIGGCCGTTPKHISAIARALSDRTPVYEKKVKQRHTVVV
QEAEQAKEPSLDDIARTRRSIIVELDPPKKLGLTTFLEGAKALKEAHIDALTLADNSLAT
PRISNVAVGTIVKQQLGMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRL
EKKIECGAHYFLTQPLYSEKQIEDVYEATKHLSTPIYIGIMPLTSARNADFLHHEVPGIT
LSDHIRARMAACANDPVQSTKEGLAIAKALIDAAFDLFQGIYFITPFLRYDMTVELVRYT
HEKERLKKERTVYHG
>A0A7Y2U6X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansiaceae bacterium|TrEMBL
MHISDIIKPHEPTFSFEFFPPKSKEAADALYETIKHLSKYHPSFVSVTYGAGGSTRELTH
DLVVKIKETTSTPPVPHLTCVCHSEDEISATLERYASVGIGNILALRGDPPTDKPDFDHS
KDSFQHAADLVRHIRRFNESGKHPDPRGFGIGVAAFPEGHPATPNRLKEMDYLKAKVDEG
ADYICTQLFFDNHDFFDFRDRCRLAGIHIPIIAGIMPITSAQGIHRMAELAGGAHFPAKL
IKALNRAGDKQQAVQRVGIHHAAEQCSGLLHADVDGIHFYTLNKSK
>A0A7X0D9P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus tengchongensis|TrEMBL
MGLLDDLKQRIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIEAGAEVIQTN
TYGANYVKLARYGLQDDVKEINKAAVQLAKQAAKGRAYVLGTIGGLRSTNKSTISLEEVK
RTFREQLYVLLSEDVDGLLLETYYDFEELQTVLSIARKETTLPIIAHVTLHDIGVLQHGM
PLTEALRQLEQLGADVVGLNCHLGPYHMLRSLEEVPIPTRAFLSVYPNASLPQYRDGRFI
YETSEQYFEETARAFRDQGVRLIGGCCGTTPKHIAAIARALPDRTPVYKKEVKQRHTIVV
QEAEQTKQPSLADIARTRRSIIVELDPPKKLGLTKFLEGAKALKDAHIDALTLADNSLAT
PRISNVAVGTIVKQQLNMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRL
EKKIECGAHYFLTQPLYSEKQIKDVYEATKHLPTPIYIGIMPITSARNADFLHHEVPGIT
LSDDIRARMATCANDPVQSTKEGLAIAKSLIDAAFDLFQGIYLITPFLRYDMTVELVRYI
HEKERLTKERTVYHG
>A0A0N0RFW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ardenticatena maritima|TrEMBL
MLMRLAQGPLLTDGAMGTQLYSRGYSFKQGFDSANIERPQVVRDIHEAYLLAGADVLETN
TFGANRVKLAEHGLQDRVAEINRAAVQIAQAAREALRQPAFILGAVGPLGRMLAPLGALS
PQEARAIFREQIQALIEAGVDGIILETFSSLAEIQEALRAAKEIAPDIPVIAQMTFGRDG
VTKLGHAPVDVAAALLANGADVVGANCGIGPRSVLAAIRTMQAQYPHATYSAIPNAGWPE
QMDGRILYPATPEYFANFAREAAEMGVRLIGGCCGTTPDHIRAMRAALDSWQAGEPIPAR
PREPVAVHVRHIAENPAPTALARAFASGHFVTTVELEPPRGVDLTDLLNTAAMLKGAGAT
VLNVADSPLARMRMSPWAVASLIQSRVGIETVLHFPTRGRNLLRVQGDLLAAHALGVRNI
FVVMGDPTAIGDYPDATDSYDIVPTGLMKLIKEGFNQGRDFGGNDLGAPTHFLVGCALNF
GAANLEREVKLLRKKIASGADFCLTMPFYDPDVPRRFIEAYGGPVEIPVLMGVLPLYNER
HAAFLHNEVPGITIPEHVLERMATAENKPQEGVRIALELIDAVRDLVDGIYIMPPFRKYD
IAAQIIRAVYRGNHANAMQEE
>A0A636CWG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Concord|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>D1Y625|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyramidobacter piscolens W5455|TrEMBL
MNNAFKEVLPNFSFEIFPPKRTGSLESIYSTVDALASLRPDLISVTYGAGGSNRDNTIEI
ASTIQNRYLLPAVAHLTCVGSSLEQTDALLAELKERGVRTILALRGDRRADADFEDGYFK
HAAELVAHIKKNYDFRVLGACYPEKHPEAPSLEADIAHLKEKVDAGVDALITQLFLNNDD
FYRFRDLAQKAGVNVPIIAGIMPITQASMLDKVVSMCGASIPPAVRRFVDAYGHNAEAVR
EAGIAYAASQIVDLLASGVEGIHIYSMNKAGVTRQIAQNIHGILYSLRVKKS
>A0A3B9LCL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spartobacteria bacterium|TrEMBL
CVSEPDRIRAIHEEYIAAGARVIETNTFGANVIRLARFGFENRVREINKAAAKLARQAAR
GEDVCIAGSVGPLGITESEAEERGIDRAECFREQIAALLEEDVDLIFLETFMSFEEMEIA
LRAKPQGDCRVVSLFACEPEGRLQSGMPLMDAFARCRELGAAVVGANCLNGPRAMVQLFE
KLPAGGLLAAYANAGYPRYTEGRYVYPTAPDYFANAAREMAAQGARLIGGCCGTTPAHIA
AVAKAIVDLRPVRSKSVRVISEPITAPLRIEHKPEESLLDKIDNGKRVIICELDPPKTLV
FEKYFTGARSLVDAGCDAITLADNSLAILRVSNLAVGAILKERFGITPLLHLSCRDRNLL
GLQSELLGMAALGMRHVLPLTGDPARVGDHPGAASVYDVNSIELISIIKQLNAGFTYAGK
PLKASPNFVIGCTFNPNAKNLDAQVQRLERKVAAGAQFVMTQPVFDVDRVEEMHRRTQHL
RVAIFTGVWPLRSARQAEFLHHEVPGIIVPDSVRGELATLDEDGARGCGMRLAEKIITAV
LEHFPGVYLITPFLQYETTTELAKFARSL
>A0A7T2U194|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia humptydooensis|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVE
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDKDSIRAFGADV
VTGLCRRLVDAGVPGLHFYTLNGAAATKIVCERLGL
>A0A7S8ESU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. INR15|TrEMBL
MIGRQRDENPEGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILV
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDDITETQVDMVK
TAH
>K2I751|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum LMG 13195|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIANTIH
GEYGIPAVAHLTALYSDEAKIDEALDMFEAAGVSAVLALRGDYIDGEEPVGRFNHASDLA
AYIHDRKPDLKVFGACYPEGHYSAASLDEDIGNLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGAKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGII
YASDQIADLVAHGVDGVHLYSMNHPATTRRIWHNVEPLFTVE
>A0A8A1M1E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces capsulatus|TrEMBL
MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTWAVDLVKYIRRTHGDYFCIGVAAYPEGHSDESYPEVQDPVKDLPYL
IEKTRAGADFIMTQLTYDLGAYKRFEEMLRNHESGVFETIPIITGLMPIQSYHILTRTTK
LSHARVPPDIMARVEAVKSDDEEVKRIGVDILCEIVNGLKQVSYPGPRGFHFYTLNLEKA
VALTVEKCNLIPPLSPLSDSETYMDTAVFMAQGKQNGISLLSKRRASSMNSQPHNRLIVD
RPSDAGGSSQASTTHETPALGAGMPALNPPPRTTTLQISEGVGALGREATWDDFPNGRWG
DARSPAFGEIDGYGPSLHVNAAVARRLWGYPTTKQDINNIFQRHVSGELHLVPWSEGGAQ
DTGGLNAETATIRDELLHLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAFV
EFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSSPATDAATEDFSGPVDVFLDS
NVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIFPRGSPTERL
LDQLKNDVWLICCVGQKYGAGCASLEAAEAEGKLLWKLLGGTGTEPDSVDKH
>A0A6A8KRF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MLDVRKLLAQRPLLFDGGMGTYYKAKPGQECEQANLTDPEGILAVHRAYLAAGADAIKTN
TFSLPRLVAAQQPGWEQLADAGWQLAAKAAGETGAAVFADLGPAPDTENLPAEQVYLAVA
KRFALLGARNFLFETLSAEDGVLEAIRALKQTVPEAFVLVSFAVLPDGYTREGRYCAELV
RRVAQSGVVDAVGLNCVSAPGAMRALVQQLGDAGLPLSVMPNAGYPVVARAQVRYQGKPE
YFARELSRLASEGVRILGGCCGTTPQHIAALRTALDALPETLPAAPATKPAAAAKPAVET
DDAFLRKLRAGQRVIAVELDSPKDADLTAYLEGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGMNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPITVFGALNLNARNFEVELRRAAEKLENGMSGFL
TQPVLSAQAVENLKKARETLGERAKILAGILPVVSQRNAIFMENEVNGIHVDDAIIQKFE
GLDRAAGEELGLEVSVQAAKAAAPYADGFYLMTPFNRVALMERLIARLRTEVTG
>M1FA24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. BSs20148|TrEMBL
MITGQLRLARFQPYILDINMESQKQFKRRFSFEFFPPKTEQGKIKLQGVRDELAAVNPDF
FSVTFGAGGSTRDRTLETVFSLHQQGISAAPHLSCVGGTRAEIKELLDTYKENGINRIVA
LRGDLPSGMGAAGELRYASELVSFIREHSGDYFNLEVAAYPEFHPQARSAEEDLKNFARK
VEAGANSAITQYFFNADSYFYFIDRLEKSGITIPVVPGIMPIVNFSSLVRFSDMCGAEIP
RWVRKQLEAYGDDSESIRQFGEEVVTRMCEKLLQAGAPGLHFYTLNQVEPSLGIWKNLGL
GERKKIPF
>A0A0S2ZQR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium hwasookii ChDC F174|TrEMBL
MKIADIYKSKNLTTSFEVFPPNDKVGLEEVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHFTCIGSKKEEIDRVLEDLERNNIENILALRGDYPVDRELEPGD
FNYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVDAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRK
>A0A0Q8UX32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root224|TrEMBL
MRNKVANAQALTRLLSQARYEVLPTASTEDKVLAHVPRDVAVTVTASPSKGLDATFDLAE
RLAGHGYVVVPHIAARMVTGRSELAEICDRLTGKQITRIFVPGGDAEPAGDYPDALSLLE
DLTELGRPFAQVGITGYPESHPTIHDDLTVQSMWDKRRYATHVVSNLTFDPAVIRDWVHR
MRGRGITMPLLLGIPGPVDRTKLLSMATKIGVGESTRFLAKHKGTFARLAAPGGFTGERF
LEQCAPTLAEPTALVEGLHVFTFNQVAETEAWRQGLLARLG
>A0A0A6UNJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes utahensis|TrEMBL
MSLGLPTRMPGAPAVGDLVRGPAPTFSFEFFPPKTPAGEQFLWQAIRELESLRPSFVSIT
YGAGGTTRDTTVAVTERVATETTLLPMAHLTAVDHSIAELRNVIGRLAGAGISNILAVRG
DPPGDPTGEWIAHPDGVRYAEDLVRLIRESGTFSVGVAAFPYKHPRSPDVESDTRDFVRK
CRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILPGVMPVTRMATIERSAVLSGAPFP
PALLRRFERLAGDEEAVRALGIETCAEMCARLLAEGVPGIHFITLNRSTATREVWQLLAP
AEIATAA
>A0A372NK87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp. WSJ-2|TrEMBL
MAHIDENPLGPHLPLDPLPGHSSMGRLERVLRRGEFAVTTELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGV
GPMASAKTAKWIRSNVPGIHIPDSVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREPNPVDQMVAERIEAARTGQEQDQQQMAEKAA
HHPH
>A0A2V2E7J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MNISDKFKQKKVVFSLEVFPPKKTSPIETIYSTFSDIWQVPSDFISVTYGAGGSDVQKNK
TCKIASLLKSEYSVEPLAHLTCLNSDKEEIRLTLDSLKQNGISNVLALRGDKNPEVEPKN
VFTNASDLVSFIKEYDSSFNVVGACYPEGHGECESLQKDVENLKNKIDAGVSHLITQLFF
DNDQFFAFMDRLEKNGIDVPVEAGIMPIINKAQIERTVTMCGASLPRKFSHMISRYASDP
LALRDAGIAYATQQIIELVSSGVQGIHLYTMNNIDLAIKINENIRSVIRSANKEND
>A0A7X6BYH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella sp. Iso12|TrEMBL
MAFHHAQHAHSLNQSLSELNGDINVSFEFFPPSTPEMETLLWNSIQRLEPLNPKFVSVTY
GANSGVRDRTHSVIERIQQETELVAAPHLTLVDASDEELLELARHYWNSGIRNIVALRGD
LPEGSPKPTRFASDLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIEAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVGNFNQLKRFAAMTNVSLPGWLHRQFE
GLDNDPGTRALVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A358M8F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKLRNLFDTKQVLSFEVFPPKRTAPVESIYDALDSLKNLHPDFISVTYGAGGSKNCAATL
EIASSIKNKYGIESVAHLPCIYLSKEDVLEMLQSFRENGIENILALRGDRNPDLPPGEDF
RHASDVISFIKENGDFHVIGACYPEGHTESDGLVNDIRNLRRKVDAGCDHLITQLFFDNE
YFYRFRERCLLAGIDVPIEAGIMPVLNKKQIERMVTLCGVCLPAKFTKMMERYEHNPEAM
RDAGIAYAVDQIVDLIAQGVQGIHLYTMNRPDTACRIHDSIAALLA
>A0A1W0A9I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thraustotheca clavata|TrEMBL
MKVIDKINAKIDKNETFYSFEYFPPKTTAGVTNLYSRIDAMAQMDPLFCDMTWGAGGSTD
KLTLEISANVQKFSGLEMVMHLTCTNMSRGSIKNALDAAKDAGIQNILALRGDPPRGMAE
FKECEGGFSYAVDLVKFIRKEFGDYFCIAVAGYPEGHPDSKNLEQDLIHLKEKVVAGADL
IVSQLFYDTSIFIEFVKRCRAIGITCPILPGIMPIQSYMGFTRMSSMCCKSIPSEIHEAL
APIKDNDEAVKDYGVQLGIKMCKELLDAGVPGLHMYTLNLERSTRLILEGLDLISPARRE
LPWRPSTMLKKRQAESVRPIFWANRPKSYLHRTASWDEFPNGRWGASESPAFGDLSGSHY
MLATQSVADRKAMWGESPTSLEDIYETFTRYCVGALKSLPWCDTPLHLETKSIQEMLASL
NRAGFLTINSQPRVNAASSDDPMFGWGGPGGRVYQKAYVECFVSPENLKHIIEKAQKMKW
IQYHAVDVHGNSYSNCGKGTTAVTWGSFPNKEILQPTIVDTDSFMAWKDEAFSLWMSMWA
SLYDQASQSFSLIKEIHDTFFLVSIVDNNFVNGNIWEVFEVDASTTATASTP
>A0A1D2TYH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. SCN 64-10|TrEMBL
MTLNDPAAPLYADLAGDCHVSFEFFPPKTEKMEAQLWSAIETLTPLQPKFVSVTYGAGGS
TRERTHNTVARIARETPLAAAAHLTCVGASKAEIGEIADAYWEAGVRHIVALRGDPPEVG
GTFSPPPEGSKGAAELVEGLMQRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFTPDAYFRFLDKTLAAGIKADIVPGIMPVSNFAATQRMAAMCNTQVPSWMGRLF
EGLDDHPASRQLVSATIAAELCRSLYGGGVRDFHFYTLNRAELSFAICHLLGLRAAASNG
GTA
>A0A2M7HES0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium CG12_big_fil_rev_8_21_14_0_65_55_1124|TrEMBL
MKLADILTQAKGPLFSCEFFPPKTDKGEENLWTCLNELRVINPAYISVTYGAGGTTQDRT
RRIVTQIKDQTGLSPVAHLTCVGSTAEDIASLLAEYRAAGIENILALRGDPPEGMDRFEA
TAGGFSHATDLISFIHKQDAFSIACATYPEGHPESKGGVADDIRYLKLKQDMGADCAVTQ
YFFDNEAYFRFLDEAAKAGVTVPVIPGIMPITNYDQIVRFSAMCGASIPDWVHQQMNPIR
EDLDAVKKLGFELAVTQCSELLAGGVPGLHFYTLNKSEATIAIVQSL
>D9R4F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacrimispora saccharolytica (strain ATCC 35040 / DSM 2544 / NRCC 2533 / WM1)|TrEMBL
MKIKDILSQGNPTLSFEVFPPKTEDKYDSVERAAAEIAKLNPAFMSVTYGAGGGTSQYTV
DIASALHREYQVTALAHLTCVSSTKEKVHQVLGELKKAGIENVLALRGDMPTDAPAKKEY
NYASELIREIKEAGDFCIGAACYPEGHVESVSKTIDMDYLKQKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGITVPVVAGIMPVTNVKQIIRSCQLSGTYLPARFKAIVDRFGENPAAM
KQAGIAYATEQIIDLIANGVNAIHVYSMNKPDVALKIKENLSEIL
>A0A2S7WYZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter glomeratus|TrEMBL
MKVTEHIKKANGKTLFTFEIIPPKKGNSIQELYNNIDPLMEFNPPFIDVTTSREEYIYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFSKEETEYLLVDCHYLGIDN
VMALRGDAMSHQKYFEPSKNGNYFAKDLVAQINDLNCGKYLHDVVEADDKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNKKYFQFVEAAKKAGIHVPIIPGIK
PIAIKRHLQLLPQVFKIDLPEILIDEIEKCKSNIDVRQVGIEWTIQQSKELLAAGVPVLH
YYSMGKSDNIRAIAEELF
>A0A2V2ER45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MHINEKFNENRPVFSFEVFPPKKNSASVESIYQAISELQELKPDFISVTYGAGGNPSDTN
TRDIAAYIKDNYHIDTMAHLTCVNADKGSIDSILRDLSSHGIDNILALRGDINPNIPPKK
DFLHASDLITYIKNSPYDFGIAGACYPEVHSEAKDAIEDVHYLKHKVDSGAEVLVSQLFF
DNNAFYAFRERAEIAGVNVPISAGIMPVTSKSQIERMVTMCGASMPAKFTHIMQRYGDNP
QALTDAGIAYAIDQIIDLLAHGVQGIHLYTMNKPYVARKIKESIKNLL
>A0A135TP13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum simmondsii|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTAMGLSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKNE
YRDTEDSETDDAEDFVWAVDLVKYIRKNYGDYFCIGVAAYPEGHADESHPQGQSFEHDLP
YLVDKVQAGADFIMTQLFFDIKAYENFEKILKEHPSGAFKDIIILPGLMPIQSYQMIKRT
TKLSHAKIPDNLMARLDAAKGDDEKVKQVGVDILSELVEQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDPKLEDEEAIIDDGPGIPVPVAVPAVQLNGLSPIPHPATRTLSN
GRRPSSMGSDPHNRIIVSGSASNPAYETTTAGLMVSEPVNTRANTLAISEGVGAVGREAT
WDDFPNGRWGDARSPAYGEIDGYGVSLHMSVTQAMRLWGTPKTVQDINNLFIRHIKGQLA
AIPWSEEELLPESNIIQQELLELNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKA
FVELFIPSSDWAGLVARLNEVKDNTICFYAANGAGDFVSSDASGGLVLEGTEASTNAVTW
GVFPGKEIITPTIIEEVSFRAWAEEAFKIWGEWAKVYGKGSESEALLERIGSEYWLVNII
HHDYVERDALWKLLSGEKEN
>A0A317VJE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus eucalypticola (strain CBS 122712 / IBT 29274)|TrEMBL
MHIKEKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPQEKVDAALQAAYKAGCTNILALRGDPPRDKEA
WEAADGGFRYAKDLVKYIRSKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGASF
VITQMFYDTDNFIDWVKKCRDRGIHVPIIPGIMPIQTYAAFIRRSNWTKTRIPPDWLEAL
EPVKNDDAAVRDIGKRLIADMCRRLIAAGINHLHFYTMNLAQSTQLVLDELNLMPSEETP
LQRALPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSLRDLTHIFVNFLEGKLARLPWSDTPITTEANAIKTSLID
LNQKGLFTINSQPAVNGVKSSHPVYGWGPKNGYVYQKAYLELLVPPYLIDELIARIEKNG
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREIVQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSPSRKLIQGVMDNWHLVNIVNNDFHNTSNLFDLFKDLDVRELDTEIPVENGEPK
AHTNGATNGTTNGATDGAAPELAVKN
>A0A095VSU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudohaliea rubra DSM 19751|TrEMBL
MARKPEISFEFFPPKTDAGRDKLLAQTAPALAALAPGFFSVTYGAGGSTRDRTFDTVTAL
ADLGLTVAPHLSFGGDDGATIGDLLERYKARGIDRIVALRGDIPSGNGAGATIVYANELV
TFIRERTGDHFHIEVAAYPEIHPQALSYESDIRYLRGKFDAGADSGITQYFYSPEAYFYF
LDRCAAAGIEAPIVPGIMPITNYQNLARFSRNCGAEIPRWICQRIEGFGDDQESIRQFGI
EVVTQLCGTLIDSGAPGLHFYTMNQVEPTRQICENLGLKGC
>A0A3D3RC03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gimesia maris|TrEMBL
MRISELYQGGTFGLSVEIFPPRNESGDAELFKTLEELVRYQPAFVSCTYGAGGSTSKRTI
ELCALIQNQLHNTATAHFTCVNSTREELVEWLQNAVDAGITNIMALRGDPPAGQETFVPA
DGGLKYANELVSLIRKHFPDMGIGVAGYPECHPEASDSEVDLTNLKRKVDAGADAIYTQL
FFNNEHFYQFREQCLKAGIDRPIVPGIMPITEYRRIQRIMSMCSSEFPADLVGQLEAAQD
DLEAQFEIGVEYAIRQCEQLIKEGVPGIHFYVLNRSQACKRIFDALGFPETQENIAT
>A0A1Y4L8S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp. An181|TrEMBL
MKIIEKLTDGKVHISVEVFPPKTDAKYKEVVDAVDKIGALHPSYISVTYGAGGGTSKNTV
NIAAHIKHDLKVESLAHLTCASSTKEEVQTVVEELKKNEIENVLALRGDIPSDRPFPIPG
GYRYAKDLICDIKKQGDFCIGAACYPEGHVENEHKEDDIRYLKEKVDCGVDFLTTQMFFD
NSIHYNFLYRIREKGIMVPVIPGIMPVTNGKQMKRICEMSGTALPARFRAIVDRFGDKPE
AMKQAGIAYATEQIIDLIANGIHNVHIYSMNKPEVAGQIMANLSEIIEK
>A0A367IS79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus stolonifer|TrEMBL
MKIIDKIAQAEKDQKINYSFEYFPPKTDLGYANLMDRIGRMTQLDPEFISCTWGAGGSTH
ERTLKLCSSAQTIHGLDTLMHLTCTNMEKDKINIALEQAKKAGIENILALRGDPPRGAEY
WTPVDTQFSHAIDLVRHIRQTFGDTFCIGVAGYPEGHIDCPSKEQDLLYLKQKVDAGADF
ILTQFFYDPEAFLKWVQKCRAIGIKVPIVPGIMPIPTYQTFRRMIHLCNVKVPESLMADL
EAIKADDQKVKDYGVQLAVKMIKQLHKEANTCNFHISTLNLERSTRLILDQLNLNLESTA
SHPNKVSPWTPIHDPAKADLWDEFPNGRYGDYRSPAYGENTYGANQILPTSQAISKWGEP
KTETDVTQLFKKYVQGELDSLPWCEESLSTETESIRQQLLSLIDRGYWTVSSQPAVNGKP
SDDPVYGWGPKDGYVYQKAFIEFFVSDKIVKDLMQHLSKDKLVTWYITNRKGDFTTNVTD
PDAQSAVTWGVFPGKEIIQPTIIEKA
>A0A0B6EZK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium singulare|TrEMBL
MSPRLSASAPLDQISEDTPERLERTALSFEVIPPRHDADAAKIDRLLATLSAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTSMRPLAHLACTAGTEQELEEWIDTLVDAGVRGLLALR
GDLPEGGMPDGHLPHADSLVRLIRRWESSRVARLAAGRLAVGVACYPSGHAESTTPDEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPTAVLDQLATATSPEEEQEIGMQITASLAQAVLNAGADGLHIYTHNNPDITTDLL
NRIGVTP
>A0A661G075|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSNAENNERETQVSFEFFPPNTEAMEKTLWSSIERLAVLQPRFVSVTYGADGSTRQRTHA
AVERIMKETNLTAAPHLTCIGASKGEIDDIAREYWDMGIRHLVALRGDPPKDVTTYVPQA
DGYAFASDLVAGLKQVADFDISVAAYPDVHPEAASAEADLENLKRKLDAGASRAITQFFF
DVSGYLKFRDRCASAGIESTIVPGILPITKFPQLQRFAEACGLKVPQWLADRFAGLEDDP
ETRKLIAANVAIEQVRMMQKEGIDEFHFYTLNRADLTFAICHVLGVRPEQAAA
>A0A6L7XWC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSRLSESLSRNAVTVTVELNPPKGTDASGLFAAAESLRRHAAAFNLTDSAASRLTMAPVA
VAHLLRDRGIESTLQMTGRDRNRLAIQADMLAAHALGVENLVCMTGDPPSGGDHPDAKAV
FDLGAEDILRASRSLEAGRDLAGNALNGSPCFYRGAVTNVEVPDLGKEVARIEGKIAAGA
QFFQTNAVYEPASFERFMARCEAFHVPILAGIIVLKSARQARYMTERIPGVVVPERLIDQ
LARSADPAEASVRSASALVRAVAPMCHGIHIMAIGWERYVPDILEAAGL
>A0A2J8USL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pongo abelii|TrEMBL
MDHRKARVLPAGHYCPSLGIWSSHVGSVRSSVPPSIRNPAMVNEARGNSSLNPCLEGSAS
SGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISRF
DRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTA
>A0A6N9CXI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSHLSDSLTHKPFTLTAELNPPKGTGLDDLYAAADALKDSVAAFNLTDSAASRMAMAPLA
VARLLEDRGVESTLQIAGRDRNRLAIQADMLAAHALGVENIVCMTGDPPSGGDHPDAKPV
FDLGAEDILKAAVSLESGHDLAGNALKGSPHFLRGAVVNVAVPDLGKEIGRMEGKIDAGA
EFFQTNAVYDPAGFEAFMKQVEGLKVPILAGIILLKSARQARYMTEKIPGVVVPDPLIDE
LESAESRVATSVAMAGRIVRNVAPMCQGVHIMAIGWEHRIPAVMEAAGL
>A0A6L8CN05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MMISQWNANPTAYLDRPVREGPLSVSVEMFPPGTESGWRGFRRSLEQLSLLGPEFVSVTS
GAGGGGSRKTLETIVKAKDGCDIPFAAHLTSIGKSRREVHGELDAAMGSGIRHVVALRGD
LPRGRARHPEGYQSALELVRAMRSREEYENCSISVAAYPEGHPEAVSQEEETGYLRRKVD
AGANRIITQFFFDTEVFAVFMERIRSAGIDVPVLPGILPIVDFPKAVAFANKCQTRIPRW
YHVMYRDLEQSVELHQAISVSIAVEQCRQLMALGVRDFHFYTLNRSELTVEVCRELGISP
ERPRASVEPGRSRPVKRIGQAASIAS
>A0A534E3F0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSDESCAMNAEPARTPIRVSFEFFPPADEAMGAMLWKSIERLAPLAPRFVSVTYGADGST
RERTHNVVTRIQRETPLTGAPHLTCIGASREEILEIARGYWDEGIRHVVALRGDPPQGEG
ARRPNPRGFRYASELVAALARLAPFDISVAAYPEVHPEAGSAAADLENLKRKIDAGATRA
ITQFFFDTDAFLRFRDALAAAGVHAPIVPGILPITRFPQVLRFAKACGTSIPGRLHERFA
GLDDDHETRRGSGLSACRQAAHGAQAPQAPQAPQAPQAPQAAPRADREARPGAGAGAERA
LAVPFAIEAVDETARATRIERLKRLLGERIVLLDGAMGTMIQQQRLDEGGFRGERFRAHG
RDLRGNNDILTLTRPDVIAGIHRSYLAAGADIIETNTFNSNAISQADYASVAIVPELNYR
AARLARSAADEFAQRTGEPRFVAGALGPTNRMASMSPDVNDPGRRSVTFEELTAAYLEAA
RGLVLGGADLLLIETVFDTLNAKAAIYAALTLFDEAGVTLPLALSGTITDASGRLLSGQT
TEAFWSSVRHARPLFIGLNCALGGRQLRPYIEELGGIADTYVCAYPNAGLPNAFGEYDES
PAETAEILREYAESGLVNVVGGCCGTTPEHIRLLREGLAGRAPRRLQAAPVKCRLAGLEP
LNIDDASLFVNVGERTNVTGSAKFRKLIEANDFATALEVARQQVVSGAQIIDINMDEGML
DSQAAMVRFLNLVAAEPDIARVPVMIDSSKWSVIEAGLKCVQGKAVVNSISLKEGEELFL
EHARKLRRYGAAAVIMAFDEQGQADTVERRVAICARARRLLTERLGFPPEDLIFDPNIFA
VATGIEEHNGYALAFIEATRRIKQELPHALVSGGVSNVSFSFRGNEPVREAMHSVFLYHA
IAAGMDMGIVNAGQLGVYEQLDPELRAACEDVILNRRADATERLLELASRYKGEGGARRQ
EDLGWRRLPVAKRLEHALVKGIDDYVIEDTEEARLAAERPIAVIEGPLMDGMNVVGELFG
SGKMFLPQVVKSARVMKRAVAHLVPFIEQSKDGRARRSNGRIVMATVKGDVHDIGKNIVG
VVLQCNNFEVIDLGVMVPCEKILETARREQADFIGLSGLITPSLDEMVHVAKEMQRQSFE
LPLLIGGATTSPAHTAVKIAPQYSGAVVYVKDASRSVGVCQTLATPAQRAAFVGKVSAEH
ERRREQHAAGRVKLPQASLAAARANRRAIDWSAHEPVAPRVPGVQRFADYPLTELLGYID
WMPFFNAWEFAGKFPDILTDPVVGEAASNLYADARRMLKALIAERWLKVNAVVGLFPASA
VGDDVEIYADESRERVLTRLNFLRQQKAKPDGQPHECLADYVAPKSSGLRDYFGAFAVAA
GEGIEEQLARFAREHDDYSGILLKALADRFAEAAAEHFHERVRRELWGYAAGESLTNEQL
VHEEYRGIRPAPGYPACPDHTEKAKLWTLLDVERAAGIRLTESYAMYPTAAVSGWYIAHS
QARYFAVGKIDREQLEDYARRKGVTREEAQRWLAPNLGYEP
>A0A6L8IFW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MPQISFEFFPPQTPRGRVNLVRTAKVLERFQPAFYSVTYGAGGSTRERTFAAVASLRESG
VNAIPHLSWSGDREDAIVALLDDYLELGVDRVVALRGDLPSGAGTSRQLRHADSLVRLIR
SRIDAPLGIEVAAYPEVHPDAPSASTDIDFLKGKIEAGATGCITQYFYNAEAYFHFRDRC
AAAGIDVPIVPGVMPISNYETLVRFSAKAGVDIPRWIQRHLDEIQGDRDALLAFGTEVVS
RLCRRLLDDGAPGLHFYTLNKAPPTRAIAERIGLPFPTG
>A0A6L8EGZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAPQFSVEFFPPRTEAGRGKLDQVHEELTTLGVNSFSVTYGAGGSTKEGTRSIVLDYNAA
GSEVAPHLSSTGQDLDVVGDLLNDYRDAGIRRLVALRGDTPPGQKRASKGFYARDLVEFV
RRHTGDHFHIKVACYPDLHPETPSFALEIKYFRQKIDAGANSAITQYFYNAESYFRFVDS
CREAGIDVPIVPGIMPITNFDKLSAFSDKCGAKIPDWLASRLAGFGDDEAGLRRYGDEVV
SELCGRLLEGGAPGLHFYSLNQAGPVRRIWENLGLSGSR
>A0A6L8DD82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MRFDDEPIEPGDPLPILPGHHSAGRFERLLRAGVFTITAELSPPDSANAEDVYARARIFD
GYVDGINATDGSGANCHMSSSGVCALLTRAGYAPVMQISCRDRNRIAIQGDVLGAAAMGV
NNLLCLTGDGVAVGDHPGAKPVFDLDAIALLNIVRTMREQACFESGRALTTPPKVFLGSA
ANPFVPPLDFQVARLAKKARAGAEFVQTQYCFDVSLLERFMQQVRDEGLDKRLFILVGIG
PLASARAAEWMRTHVPGVRIPDAVIDRLRRARGKGAAKAEGKRICIDILERVREIPGVCG
VHLMAYRQEEAVAEIIDRSRALDGRIPWYPGRDRHSRPAREVDSPTELPEEMLA
>A0A521WDF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MEWTEPAMYPVRLWSVRHARGLQRAYRWFAAHAPRLAPLLRRLGPRRGEALLYPIERTLK
RFLFDCQECGQCVLSQTGMACPMNCPKQMRNGPCGGVRPDGNCEVDPGMRCVWVEALEGR
RRIHAGGEAGAAPVLPAVDARRRGRSTWITVIHGEPEPVVTAVPVGTSRPERAVESFEAA
CRSGRSVVTVEVAPPDSADPADLLARAARFKGLVDAINITDGAGGNCHMSSVAAAALLAA
NGYVPVYQTVCRDRNRIAIQGDLLGAAALGVRNVLCLTGDDVTRGDHPEARPVFDLDAVT
LLGIARGMCERGEFASGRRLLAAPEFFLGATVNPFVPPRDDRIANLEQKIAAGARFIQTQ
FCFDVPMFERFMAEVRRRGLHQRAFILAGTGTLASARALRWMAQNVPGVYVPAELLRRIE
AAADQKAEAMRACIETVQALAGIEGVAGVHLMGHRNEDVLAEVIVESGLAMRVRPS
>A0A429K2P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter lactucae|TrEMBL
MLVEYLTSLHEIYPVKHELAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGK
ARDIQDFECFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLIKHNYSQ
QILACVMPLTLARANFMVKHKVAGIVITPHMLKVLEDEKQVGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYVEQYRHLKLKALEELWNSLWQVTTGKEFAPEIMHFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAKLLLKTEVLSKHSLV
GCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAIEQT
EILKEKLIPTVPIETRGTSSWKNWYLATEA
>A0A7C1XCT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDSQKKYTPTFSIEFFPPKTEEGKAKLRKTREELAKLTPAYISVTYGAGGSTQQGTVDTV
REIHQSGIDAAPHLTCVGAGKESIRELLQTYIDNGIHRIVALRGDMPSGMREMGEFRYAN
ELVAFIRAETGDHFHIEVAAYPEVHPQAGSVSADLEHFKLKVEAGANSAITQYFFNADAY
YRFVDDCEKTGLNIPIVPGIMPITNYKNLARFSDMCGAEIPRWLRKRLEDFGDDVESLRD
FGQQVTTQLCKDLLEQGAPGLHFYSMNRVDPTRAIWRDILPS
>A0A2G6EFD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MRYDDEPVPGYPLPIRPGHSSPGRFERVLRDGHFAVTTEIAPPDSADPNQVYERAAVFDG
HVDAINATDGSGAHCHMSSVAVCALLSRIGYSLIQQVSCRDRNRIAIQGDVLGGAAMGVC
NLLALSGDGVQTGDHPEAKPVFDLDCMSLLEIVSTMRDKQTFQSGRKLDSPPRMFLGAAA
NPFVDPLDWRPIRLAKKIAAGAQFVQTQYCFDITRLDAYMQRVRDMGLDRKVFILVGVGT
LASAKTADWMRRNVPGVHIPDEIIKRLAGAENQKAEGVRICIDMINQVREIEGVDGVHIM
AYRQEHSVPEIVERTGILGDRQAWHPRQYEGDRNVQQHLDRIQ
>A0A381CDN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buttiauxella agrestis|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATREELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNYKQAHKFATMTNVRVPHWMAQMFE
GLDNDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>W3XZB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. SR4|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKDQAPQFDIIGACYPEGHPDSANQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHEATHSLFKHHSQVGAL
>A0A1G0DZE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium RBG_16_57_15|TrEMBL
MNKPLFSFEFFPPQTPEGAEKLVAVRRQLAALHPDYFSVTFGAGGSTRERTLEVVQQIKA
EGLEVAPHLSCVGSTRENIRNILQTYKQLGIRRIVALRGDLPSGMATAGEFQYANELVSF
IRAQTGEHFHIEVAAYPEVHPQARSARDDLVNFKRKAAAGANSAITQYFYNADGYFHFVD
ECRKLGVTLPIVPGIMPIVRFAQLARFSDTCGAEIPRWIRRTLEGCGDDSESVQAFGLDV
VTQLCEKLLAGGAPGLHFYTLNQSGPALEIWKRLGI
>A0A3D3BLL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTFDSKVTLKGWSIEITPKETKTISCFSAFLEEGTKVNVTSLPKTSVRDTLAAVEKLKH
DGMNPIPHITARTIADEGDLARIVEKYADLAISEVLIIAGTKDQATGHFSSSADLISSGV
FEHFGIVNIGVAGHPEGSPDITEKQLQDALDQKNHLAVSRNLNIFLETQFCFDAQRIINW
EKAIRDRGNSLPIRVGVAGPTKLLSLINFAVKAGVGPSLKFLINERDKLTKLVNSYDPTE
LIYSLAPQFSPEANTCFESVHFYAFGGFRKTAEFAQELFK
>A0A3D5W6L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MHSVNSSDPGQPLPILEGHVSAGRLERVLRSGKFAVTAEIAPPDAADGEAVYRRASMFDG
CVDAINATDGSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVT
NILCLTGDGVQAGDQPDAKPVFDLDCISLLQTVTAMRDQGEFLSGRKLTTPPRVFLGAAA
NPFGPPLDYRPVRLEKKINAGAQFVQTQYCFDLERLRTYMMRVRDMGLTERCYILVGVGP
MPSARTAAWVRDNVPGVHIPDPVIKRLLDARDQREEGVRICVEIIQAVREIEGVHGIHIM
AYKQEERVREIVTESGVLEGRTPWYPGVGNDHCGQQK
>A0A432EQF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
CGAEIPRWLRKRMEGYGDEVEKMQASATDVVARLSRQLLDAGAPGLHFYTMNKVEPTREI
CQRLGW
>A0A353R2Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
RGDLPSGMGDPGALRYARDLVRFIRSETGNHFHIEVAAYPEIHPQAQNARDDLANLCDKV
RAGADGAITQYFYNLDAYTQLIAEVRASELDVPVTPGIMPILNHAQLARFSDSCGAEIPR
WIRKRLEGLESDEQALRAFGHQVVTDLCRRLLTHGAPGLHFYTLNQAEPTLHICRELQSL
TIAN
>A0A534CQZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGSANFTAHTPIRVSFEFFPPGDADMATTLWKSIERLAPLAPRFVSVTYGADGSTRERTH
SVVTRIQRETTLVGAPHLTCIGASRGEILDIARRYHDEGIRHVVALRGDLPQTQTRYQPH
PDGFAYASDLVAGLRAVADFDISVAAYPEVHPEAPSAGFDLDNLKRKVDAGASRAITQFF
YDIDVFLRFRDRCAAAGIHAPIVPGILPITRFPQVLRFAARCGASIPPWLKERFQGLDDD
HDTRRLIAASVAIEQVHALVRHGVREFHFYTLNRAELTYAICHALGIRPATQSPAAAAYQ
PGVPA
>A0A2E8I329|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionaceae bacterium|TrEMBL
MVYTVELLPPSGVXLXSLLAKADLIXEAGVDCIXIPDGPRASARMSAILTAVMIEQKXGI
ETILHYTCRDRNLLGMQSDMLGANGIGLRNMLLVTGDPPKMGVYPDATGVFDVDSIGLTN
MVXKLNGGIDLGQRPIGEPTRLSIGVGVNPVHHNMPYEMKRFKYKIEAGAEWAITQPIFD
VDTFFRFMXIXSSMXXKTPIIAGIWPLTSLRNAEXMNNEVPGIVIPXSIIKKMSQYSDPI
DAKKVGVEIAQXMXAKIEGSISGVQVSAPFGRIDMALTAIGKS
>A0A534J676|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPIRPGHTSPGRFERVLRAGQFAVTTELDPPDSADPEEVYRRARVFDG
YVDAINATDGSGANCHMSSLAVCALLTRVGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQALPVFDLDALTLLETARTLRDEHHFLSGRKITHAPRVLLGAAE
NPFAEPIEWRAERLAKKVAAGAQFIQTQFCFDVPLLRTFMNRVEDLGLLDKVFILVGVGP
LRSAKSAEWIRTHVPGVHIPDEVVKRLAGASDGALEGRRLCIDVIQEIRTLKGVHGVHVM
AYRQEEAVAEIIQRSGVLGGRVPWNPGRDPPANTNRMASEPTPSAALEPARS
>A0A534BSR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPILPGHTSPGRFERVLRAGTFAVTSELAPPDSADPEDVYRRARIFDG
HVDAINATDGSGANCHMSSLAVCALLTRLGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQALPVFDLDSLSLLETARTLRDEHRFLSGRRITCAPRVLLGAAE
NPFAKPCEWRAQRLAKKVAAGAQFIQTQFCYDVPLLRAFMRQVEELGLLDKVFILVGVGP
LRSAKAAEWIRTHVPGVHIPDAIIKRLAGASDAALEGRKLCIDLIQEIRTVKGVHGVHVM
AYRQEETVAEIIERSGVLGGRVPWYPGRDPQANTDRMAS
>A0A534DY90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPILPGHTSPGRFERVLRAGTFAVTSELAPPDSADPEDVYRRARIFDG
HVDAINATDGSGANCHMSSLAVCALLTRLGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQALPVFDLDSLSLLETARTLRDEHRFLSGRRITCAPRVLLGAAE
NPFAKPCEWRAQRLAKKVAAGAQFIQTQFCYDVPLLRAFMRQVEELGLLDKVFILVGVGP
LRSVKAAEWIRTHVPGVHIPDAIIKRLAGASDGALEGRKLCIDLIQEIRTVKGVHGVHVM
AYRQEETVAEIIERSGVLGGRVPWYPGRDPQASTNRMAS
>A0A2E0N0X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MXKNXRSFSFEFFPPKTXQGKXKXKAXAKKXEFXSPEYFSVTFGAGGSTKQGTIEXCISI
ASNSXXACPHLSGIGSSKEMIKQILNKYKSNGFKRIVALRGDLPSGIGGTGDFPYAVDLI
EFIKDTEENKFHLEIAAYPEIHPEADSEKRDFDNFLNKIKAGASGAITQFFFDPEPYFKF
MEKCEKNRVSIPIVPGIMPIHNSEALLRMSKNCGANIPPWLVKGMARYSKEHDFLKYGIE
IISNLCLKLIDFGAPSLHFYTINKEEPTISIIENLR
>A0A349N887|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSTDTSHFSIEFFPPRTPAGEEKLDAVHAELSKLGPEFFSVTYGAGGSTRDGTKRAVTRF
REAGSCVAPHLSFGGSNETEILTLLHEYKDAGVDRLVCLRGDAPSGMGSASLYRYANELV
EFVRKETGDHFTIDVACYPEVHPQSRSVESDLEFFKAKVDAGANSAITQYFYNADAYFGF
VDDCARAGINIPIVPGIMPITNYANLARFSAACGAEIPRWLTKRLEFLEHDDQALRDFGL
EVVTDLCEQLLAGGAPGLHFYSMNQADSVTRLWQNLLED
>A0A2D9SRH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKFSSKLKQGEFVVTTELTPPKGTDXTALLATAASLENHXDAFNITDSHXARMSLSPLAA
ASALVQAGLDPILQMTTRDRNRIALQSDMLGAGCLGVENLVCMGGDPPHLGDHPDAKPVF
DFSTLELLDAANKLNAGIDSTGNKLNKAPVFNIGAVVNPGADNLDKEIDRLKEKIDNGAT
FFQTQAIFDVSAFERFCNRVAXFDLPLIAGILPVKSXKMAAYMNSNVPGINVPASIINRI
SESKSVKATSXEISAAIVADIKPFCCGVHLMAIGWEALIPAILEQAAVR
>A0A0W7WND8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ponticoccus marisrubri|TrEMBL
MRPEISFEFFPPRNIEGTFRLWDAVQVLAPLAPRFVSVTYGAGGTTRDLTREVVATLHKH
SGLRTAAHLTCVNATRDETLEIARGFAEAGVADIVALRGDPPKGSARFEPHPEGFGNSVE
LIEALAATGDFTIRVGAYPDIHPEAASAQADIDWLKRKLDAGATEALTQFFFEPETFFRF
RDACAKAGIDQHVVPGILPIENWKGARRFAESCGTHIPGWVIDAFDKATRDGREDLLATA
ICTELCSELIEGGVDKLHFYTLNRPELTRDVCHALGVTPEVKLENVA
>A0A8J4N843|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eudyptes sclateri|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAIDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWTEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A2Z5SHZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sulfurreducens|TrEMBL
MTFLERLHDEVLIGDGAIGTMLYAKGISLDANVEHLNLVRPSLVLELHREYLAAGARVIE
TNTFGANWTRLAAIGLEKKEREINLRGAQLAREAAQGTDAFVAGSVGPLVRMKGDERELS
ADETVDIFRRQTHALAEGEVDLLILETFTDLAQMRHALTAARETGLPVVANMAFLENGRL
AGGIEVERVAVELTAAGACVVGANCGAGPLEILGTIQRMGRVTELPLAAYPNSGFPEYVN
GRHVYRTTPDYFADRAVEMVGAGAALVGGCCGTTPEHVRRLAERLAGLRPVARTVAVPAL
PKEARRAESRDDAGFLARWGREPIVTVELDPPKGLDCAKIIEGSRALREAGADAINIAEN
PLARIRMGNIALGSLIQREAGIDVIVHVTCRDRNLLGLQSDLMGASLLGIRHVLAVTGDP
ARIGEQAGATSVYDLNSFGLIKLLADLNAGVNALGSPIGGGTGFVIGAAFNPNSARMEVQ
VERLARKVANGARFVQTQPLYDVARLEEMAERTAHLGIPILPGILPLVSERNCEFLHNEV
PGIVIPEEIRHRMRGKEKEDGVREGLAIAREFIDAVRDRVGGFYLIPPFGKYGIAVELTR
YIKGT
>A0A7X2H2N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus monticola|TrEMBL
MKPDLRSAWEKKVLVGDGAMGTFLYQKGFPVGISYEELNLTSPGVIEDVHRSYIEAGAVL
LESNTFSANYDKLSKYGLETKVEEINRAGVRIARRAAGDNGYVVGAVGSIRAGKRANLSS
SELKKYFSQQITALLEEEPDGIMLETFYDVEELHLALRTVRKISALPVICQLAVDESART
LDGLTLPEAFRILEGDGADIIGFNCRTGPNGIKRALKSLQGSLVLPVSVYPNAGVADYVD
GEYRYGASPEYFGQMALSFAEMGSRIIGGCCGTTPQHIAEISAALQGYVPQPLPVPAAQS
LNRITVHEHFSEDEGTGGGEPTLVDLVKERHTVIVELDPPRDLDIAKFMKGAEALRRAGA
DALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGIDH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKAKFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDTELIANIAQATKYLDIPVFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRRRMDGLEGAVGRAEGVAIAKELLDAATEHFNGIYLMTPFMFY
DMSAELLEYVWKKQGRKLSPLFR
>A0A6C2USQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontiella sulfatireligans|TrEMBL
MRRLKDSLLNSPDFTVIAELTSGQGYSMDPIVRFLEAHKASGGSEIPKGFDFASIALPQN
PGGISNLDPTDVLAQLSGTGLLDDLDFIPHMSCKDHNKAALHSVLVGYKQRGVQSVLALT
GDKPVSAKGVFELEAVGLLQLISKMNLKELLKGGHDDLSQIPQFFSGAAVSPFKYSEPSQ
LQQYFKMEKKAACGARFFITQVGWDWKKSLELKFYMEEAKLNLPVLGNCYFLTSTNAAPR
LMNSGHLPGCYVSDELLATLKSETKEQHIERCAQQIAMYRAMDYAGIDLGGIHDYETFCI
ILQRAAEIGEGWVEFQDNLCRPPEATFYLYDQEGGRTPLAPGKKPCTSAGSASCTKPCST
PATKASMD
>A0A4W2CPV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos indicus x Bos taurus|TrEMBL
MVNEPRGNGSPGPRWEGSSSGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKH
IRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVK
ACSEIGITCPVLPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQAEPPPPASCFLPSEHPVQEAVCLALLP
AAQGL
>A0A1F2P6X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Syntrophoarchaeum caldarius|TrEMBL
MGEAFSELMKKIKAGEFVYTGELEPHNLSTEIGDVVEWAKTLKGIGKITAANVTDNPQSF
SAMSSLAASFIIQRDSGLEMVYQLRTADKNRLALASDILAAAAFGLKNILALTGDHTHMG
NTPDAKPVFDLDSAQLVDLIHHMVYEGTDLSGNEVQGPRPEINIGVAGNPNQEPLEIEVL
KMERKAEVGADFIQTQVVFDVDIALTYLESIEHIGIPTFIGIFPPRSYGQAEFFDKFVSG
VTVPPEFLKTFKEFKAISDKAERKKKIDEFNIDYFVNFVKEIRKKKNCAGCHIMAVGYPD
VIAPIIEGAEK
>A0A5D0PUG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbispora tritici|TrEMBL
MALGLPSRLPDRVPTVRELLAAGERSFSFEFFPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPRGGDPMDEWVRHPEGVLYAEDLVRLIRQAGDFCVGVAAFPYKHPRSATVESDTRYFV
QKCRAGADYAITQMFFRAEDYLRLRDRVAAQGCDTPIIPGVMPVTQMSTIARSEQLSGAP
FPPEVAERFAAVADDPVAVRRLGIEHAAEMCRTLLDEGAPGIHFITFNRSSATREVFQAL
HGVPAVAG
>A0A4R4NS76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea longispora|TrEMBL
MSGLRAAFEAGRFAVTAEIGPPGGADAEAVTRKADLLRGWVDAANVTDNQGANVRMSSLA
GSVLVQRAGVEPVMQLTCRDRNRMALQSDLLAAGALGIPNVLLLTGDHPRFGDHPEAKPV
FDLDGVQLVWTARTLRDDGVLISGKAVSARPAWLVGTVENPFAPPPRFRARRLAKKVSAG
AEFVQTQYVFDFEVFERWMADLWDLGVTDHCKVIAGVGPIRSLRALEYMRTAVPGVHVPD
EVDRRLRGVPADRVAEEGIRMCVEAVQRLATIPGVAGVHLMALGFEHGVPDILRRAGIPR
PPAALPDHNRHPMEGIGHAR
>A0A286BU05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium JKS000234|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRGIARDYWDSGIRHIVALRGD
LPPGGGKPEMYGSDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAASIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMSAMFE
GLDNDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGISA
>A0A2I1CV01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus campestris IBT 28561|TrEMBL
MHIKDKLAQNEAAGRTGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMGIEKVDAALQAAYKTGCTNILALRGDPPREQEH
WEAVDGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNSDVDQLIDHLKEKVDAGSSF
VVTQMFYDTDNFISWVKKCREKGIHVPIIPGIMPIQTYAAFLRRANWTKIHIPPSWLEAL
EPVKNDDAAVREIGKVLIADMCRKLMASGINHLHFYTMNLAQSTQQVLGELNLLPSEETP
LQRPLPWRPSLGLNRRGEDVRPIFWRNRNSSYVARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSVRDLSHLFTRYLEGKLDRLPWCDTPITSEANEIGGELLE
LNKRGLLTINSQPAVNGARSSHSVYGWGPKNGFVYQKAYLELLVPPYLLDELIARIEKNE
DLTYHAVSKSGELRTNTRDTPNALTWGIFAGREIVQPTVVETVSFLAWKDEAYRLGEDWA
KCHDAASPSRKLIQSVVDTWYLVNIVNNDFHNTYNLFELFKDLDVKDLDVEVATEQKAQP
TVAVNEVTPEVPTKN
>A0A261WNP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas avellanae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKNAGIKRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A1E4Q5G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. SCN 68-63|TrEMBL
MPAISFEFFPPKTDQQRAQLDRTAQLLKKVQPDYASVTFGAGGSTLSYTGETVARLHREH
GLPVAPHLSCMGGTRAEIAALLDGYRAAGYRRIVALRGDLPSGMASPGDFRYAAELVRFI
REHSGDHFHIEVAAYPETHPQAEDALADLRHFQAKVEAGANGAITQYFFNPDAYFRFVDD
VRALGVTVPIVPGIMPISNFSQLKRFSDACGAEIPRWIAKRMQAHGDDAEAIAELSAQVV
AGLCRRLLEGGAPGLHFYTLNRARPTLAILDLLH
>A0A1J4XKA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon CG1_02_33_12|TrEMBL
MRVTGIIKQKKWEIISVEIEPPSVDEGIEKVYEILNPLVKKGICYINITNHAEKIEKNGD
ESLSFQIERPGTIGVAGVIKEKYREKGVIPVPHIICTGLTRSDIERTLIDLNYLGIENVM
ALRGDPPKLNGNFMEFKPKENGPSYAKDLIKQIADLREGIYTGTKKKTKIDFCIGAACYP
EGYYKSQALDENINWTKAKVDAGADYLVTQLFFDNNYYLRFIEEAENAKIKVPIIPGIFP
ISLYAHLEKLPEVFGCSIPKEIIDKVEKYKYDEEDIKKVGIEWCVKQCLNLLEKGAPSLH
FFANRGAPIEEIIKGVYNPK
>A0A6G7PU19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosulfuriphilus ammonigenes|TrEMBL
MKSGSHLEKVLTSGEFAVTAEIGPPKNADPEVVLEKARLIKGYVDAANITDCQTAIVRMS
SIASAVLIMTEGIEPVIQMTCRDRNRIAMQSDLLGAAALGIKNLLCLTGDHHKFGNHPQA
KGVFDLDSIQMLAMVREMRDERRFQCGEEIKGQEPRFFLGAAANPFADPFEFRVYRLAKK
IEAGADFIQTQIVYNVERFAKFMEMVRDLGLDKKVYILAGVTPFKSAGMANYMKKFVPGL
DVPDDLLKRMKEAKDPREEGIKIAVEIIGQLREIPGVAGVHIMAIEWEAAVPEIVKAAGL
YPRPEMEEVEPTVRLVSKEPLEVTPPKEEAPEEVAPEAPPQVTPPAAPSLPIEALKEVFS
VLKAGIGDLMKGAEALTKGIAGLEETLLGAGAEARPSEPSPPSAEVPPPPEAPAEAEAPA
EEARKREEEEKAAKVASLITAAKAALDAGDLDKAEGHFKEVLELEPENAPAREGLTEIKE
RREIAELLAGARTALEAEDLDKAKESFEAVLKLKPDHPEAKEGLSRVETLIAEREKEAKE
AEPPKEEAPPAPVEALEFELAREEKSLFDRLRSIPKDVVLDPANGEIKEVTIGVGDKAIA
AGGTNALPFHLFEGEMKNPPRIAMEVLDTKPEEWPEPLLRYFGDVIGDPAAWAKKCVESY
QAEAICLYAVGADPNAQDRPAEEVAQVAKAVSEAVDVPLIIWGCGNAEKDTEVMRQVAEV
VGPKNVLIGPVVDQNYRQLGATALAYQYPVVASSPIDVNLAKQLNILLENLGVPLERILM
DPSIGALGYGLEYTYSVMERIRLAALYQQDDKLQVPFICNLGREVWKSKEAGLPSDDLLG
DQERRAVLMEAITAVCMMLAGGDFLIMRHPRAIALAKALIKAMV
>A0A8E2G9L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. HMSC036E02|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEAT
>A0A367ZY34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Tokpelaia sp. JSC085|TrEMBL
MSSYGFLCPESIKVSFEFFPPRSENIGKKLWRTVERLALLQPHFVSVTYGAGGSTRERTI
HTVARVLRETALVTAAHLTCAGATCEEVERIAREFASLGVRHFIALRGDPENGHGDTYQS
TTGGYANAVELVAGLKAINNNFDISVSAYPEKHPESPDFATDIDLLKRKIDKGATRAITQ
AFFDNDQYESYLEKIRAAGINIPVIPGILPIHNFWHVKSFCSRTCTGIPFWLAHRFEGLE
NDPKTHAHISAFVAAEQVLDLIKRGVKEFHFYTLNQADLTYTTCHLIGIRPKKRIKVG
>A0A2K1R1R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaceloma murrayae|TrEMBL
MERISDKIAALPQDGNYFSLEFFPPKTQQGFDNLQSRLSRMSQALRPLFVNVTWGAGGST
STKSLALAELTQRQLGLTTCLHLTCTNMSRRLIDETLEQAKALGVRNILALRGDPPRSEE
YKAENGDAPECEEDDSNKDFTWAVDLVRYIREKYGDLFCIGVAGYPEGHSDQSHPEHQSM
GFDLPYLVEKVQAGADFIMTQLFYDIEAYEAYTKLLRSHESGAFKDIHIIPGLMPVQSFQ
ILRRTTKLSHAKLPESVLKRFEQVKGDDEAVKRVGVDVISEMVESTKKSSQKGPKGFHFY
TLNLEKAVAQILQRCDLIPPSTPSIMTSLDSAISEEDSDGYLLVKHEDRERKRRVSREAN
NRLIVDRSRATSTHSSLYEASEDEVAGKSDLPPSRAAALAISEGEGNMGREATWDDYPNG
RFGDARSPAYGEIDGYGVSLHVSIPQALRLWGRPATKADITTIFEKHVRGEVEAIPWSED
SLNAETETIREQLAALIKKGWWTIASQPAVNCVKSTDTIFGWGPSNGFVYQKAFVEFFIP
SADWKRLKGILDQDDQFTYFAANDGGEFDATNEQGVNPVTWGAFTGKEIVAPTIIEGMSF
KAWADEAFGIWREWAVVYKPGSETSKLLKGIREDYWLVNIIHHAYVEPEALWERLAEI
>A0A4R1XTM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus|TrEMBL
MSKRVPISFEFFPTKTDAGAEKLRVVHQELLPLAPEFFSITYGAGGSTRERTLAAINDFN
GQGVPVAPHLSCIGDNKGRIAELLDLYKDLGINRVVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFQIEVAAYPEMHPQADSFDADIHRFVEKVQAGANAGLTQFFFNPDAYFYFV
DRIQKAGIDIPIAPGIMPLTNASNLIRFADGTGAEIPRWIRKQLQAYGDDSQSIKAFGHE
VVLNLCERLLAGGAPGLHFYTMNQTDPTRQLVLDLGLAKA
>A0A3D5S7S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagales bacterium|TrEMBL
PAKNITEKVDAGAQFVITHTCLDMDLLRLYMQRLSEIKLLWRCHVVVGIAILSSAEDAQW
LRKNRPNVNIPNDIVTRLSNAKDPKKEGIAICVEQLQELSTIPGISGAHIIAPEKLTNIP
VAVDQSGTYKKKTN
>A0A558DC22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sedimenticola thiotaurini|TrEMBL
MTANQTDKKLFSFELFPPKTEEGMLKLQTHVKKLNRINPQYVSVTFGAGGSTQQRTFQSV
EWLVSQGIEAAPHISCISSSADEIITMLNSYKSQGIKRIVALRGDLPSGTGLAGRGELNY
ANELVALIRSTFGDHFHIEVAAYPEFHPQAANADADLNNFKRKVEAGANAAITQYFYNAD
AYFKFIESCERLNINVPIVPGIMPITNYSSLSRFSDACGAEIPRWIRKRLEAYADDVESI
RAFGLDVVSELCQRLLDNGAPGLHFYTMNQSGPTLKICDNLNVAEQNRA
>A0A1T3VP71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter enzymogenes|TrEMBL
MLPISFEFYPPKTDDQRSQLDKTAAKLRGFSPSYVSCTFGAGGSTLSYTPETIRRLRGKH
GLDAAPHLSCVGGTRGEIRQLLELYRELGCGRLVTLRGDLPSGMASAGDLRYANELVEFI
RAETGDHFHIEVAAYPETHPQARDALSDLENFKRKVRAGADGAITQYFYNPDAYFRFVDD
VRAAGIDVPIVPGIMPIANFSQLRRFSDLCGAEIPRWIAQRMQAYGDDADSIREFAADVV
ARLCSRLIEGGAPGLHFYTLNLAKPTLSVLSRIA
>A0A3D5RWI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophagales bacterium|TrEMBL
MKVTEHIKAAEGKTLFSLEIIPPKKGDSIDSLFNHIDPLMEFKPPFIDVTYHREEYVYKN
RGNGLLEKKTIRKRPGTVGICAAIKNRYNVDPVPHIICGGFTKEETENALIDLNFLGIDN
VLVLRGDSIAEEKTFKPEPDGNAYAIDLVDQVVGMNEGQYLDEDLQNAVPTTFCIGVAGY
PEKHFEAPNLTSDLKYLKQKIDHGAEYIVTQMFFDNQKYFEFVDKCREAGINVPIIPGLK
PITAKSHMTILPSIFHIDIPDELYTEIEKCKDNKQVKEVGIEWGIKQSKELMAAGVPVLH
YYSMGKSDSVERIAKSLF
>A0A077XMW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. (strain PM2-P1-29)|TrEMBL
MKIVDHISNAKGKTLFSFELLPPAKGQGIQSIFKTMDALMEFKPPFIDVTYHREDYMYKK
HESGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDSDFIPTDGGHAFATDLLQQVVDMNQGQYLHEDIAISEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVTKCRENGIHVPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSEAVSACKSNADVRQVGEEWLVQQCKELIDFGAPVLH
FYTMSNPGPTKSIVEKLF
>C8WWX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / BCRC 14685 / JCM 5260 / KCTC 1825 / NBRC 15652 / NCIMB 11725 / NRRL B-14509 / 104-IA)|TrEMBL
MWRQWRRPPRDVEGPLGAYVIFDGAMSTYLHQLGVPIGTPVEQLNLTSPDLVARVHRRYV
ESGCTVLQTNTFMGNRIALERHGLTVDVQSLNRRGVEIARSAARDEASVYGTMGPAMGGY
RYGALLQDEERDLLARVYAEQAEALVSAGIDGLILETFPDLEEALVAIAAVRPILGDLPL
VVNLSPEEIGVTRDGVPLAEAFRRIKAAGADVVGLNCRLGPYGILRSYEQAGVAADGPYA
AVPNAGILQRSEGDEIAYTGDTADFSRLMLRIAQLGVRWLGGCCGTTPEYIRTLRDALMR
ADREPHGAAIQAETHATSRPSAVTTGAGAYHDGMSVVDIAREKKAIVVELDPPKHLSIAR
FLEGAEALAGAGADLITMADNSLGSVRVSNMALASLLKQRGIEPLVHVTCRDRNLIGQQS
HLMGLAVLGIRNVLLVTGDPSRYGELPGATSVYDVSSMDLTKMVRRLNEGIGFSGQPLKQ
PSRFVIGTAFNPHVHNFRKAVERLRRKVEAGADFVMTQPVFDPNLMAAIAEATRDLGVPV
FVGIMPLTSARNAEFLHHQVPGIRLSEQALRRMQEAAPEEAPAVGEAIARELVEVAIRLF
PGIYLVTPFLRYEMTVRLTEYARSLEATLVSRPHGHA
>A0A852VZ42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia antarctica|TrEMBL
MTSVQNERTPAAGRPTGRQALARALRDATYEILPFRSAEEKVLAHVPTDVALTVTTTEAK
GLGPTIDLAVRLGEAGYRAAPHLAARQVRDRAHLEDLVARLREAGTDSVFVIGGDAAEAG
EYPDALSLLQALKEIGHPFSTVGIGGYPEGHGKISDELIEAALKAKAPHATQVITQLCFD
GDTTVDWARTVAADGVGLPIRVGIPGAVSRQKLIRVSAGLGLGQSAKFLSKQQNMLWRFF
LPGGYSPNKLVERLTPAFARPDNNLAGFHVFTFNDLDSTEAWRQRWLATLS
>A0A077P1Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus bovienii str. kraussei Quebec|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPSTTTMEQTLWKSIERLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKDKTGLDAAPHLTCIDANREELRNIAHDYWESGIRHIVALRGD
LPDSSGKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A8H3IFP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alectoria fallacina|TrEMBL
MEKITDKIAALPSDANYFSLEFFPPKTQIGFSNLQTRLERMSSALRPLFITVTWGAGGST
SSRSLELAEICQRQLGLTTCLHLTCTNMKRKVVDEALEEAKVLGVRNILALRGDPPREEE
YRLEDETEDGEDEDDGNEDFTWAIDLVRYIRRVHGDYFCIGVAGYPEGHADQSHPMDQDP
LHDLPYLIDKTKAGADFIMTQLFYDVQAYSKYERMLREHESGTFAKIPIIPGLMPLQSYE
ILMRTTKLAHAKVPPDLLHKLQGVKGDDEAVKQVGMEAIHDVVESIRDVKAKGPRGFHFY
TLNLEKAVSSLLERCNLIPPDPEENKVSAVDDISILVNGDAVHHRALSSTSSSAAAQLTT
NTHRSSSPARPIPPNSNPLSREATWDDYPNGRFGDARSPAFNPPLTYSPTSLTVSPAQAL
SLWNTPTTPEEIDCLFTSHLAGRNPVQLPWSESATLSPETALITSELTQLTRTKGYWTIA
SQPAVDGLPSTHSIHGWGPPGGFVFQKAFVEFFVPASTFNTTLRAHLDRLSKEGEISFYA
GNAAGAFQSSENSEAVHAVTWGSFAGKEIATATMVEEVSFRAWVEEAFGIWGEWARCAGE
AARRGRADKARESRDFLRRIGKDVWLVNVIGHGYLEGGRLWEVLMKG
>A0A7Z0SDR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanofishera endochildressiae|TrEMBL
MKPIYLVLNFYPPKTEQGDVNLEQVHRDLAKLNPDFFSVTFGAGGSTRDKTYDTVVKIQN
NGVSAAPHLSCVASTKENIREILSNYRERGVSKIVALRGDLPSGMMSAGEFRYANELVDF
IRAETGDHFQIHVAGYPEIHPQANNATEDFNNFKRKVDAGADAVITQYFYNVEAYFYFLD
KCAKSGIDIPIVPGIMPITNYAQLFRFSDMCGADIPRWMRKTLECFGDDKASILAFGEDV
VTKLCQQLLDSGAPGLHFYTMNQSKPTLAVWNNLRF
>A0A2N2NL06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-3|TrEMBL
MNEQNKFIESISLEKPIISDGAMGTVLHQRGIRFDECFDHLNITHPTQVADVHHAYIEAG
STMIQTNTFGANHYKLSQFGLEHKVAEINQAGVELVRRVAMASFRDIIIAGDVGPLGVRL
APFGRVQLEDARDAFKEQIQALIDAGVDVIIIETMTDFYEVREAILASREINPDIPIIAS
MTFTRDDRTLLGDTPEKVATSIYNSGADVIGINCSGGPLQLLRILKKMKTAVPNGVYSVM
PNAGWPEQQDGRIMYPAGPEYFGDYAISFWQTGAKVLGGCCGTTPKHIQAISRIIHDTKL
SDIAFGVEKPEMQVEGEAEKEAPKSELSQKIDANQFVFAVEMDPPRGLSTKKLLAGASLL
ADSGADVINVADSPMARMRMSPWAVCSLIQRYVGIETVLHFPTRGRNLLRVQGDLLAAHA
LGIRNVFVVMGDPTAIGDYPEAMDNYDLVPSGLIKLIKESFNIGIDHAGSEIGQPTSFFV
GSALNLNSPSPEIELKNHLRKRKAGSDFVLTQPIFDAKSALDQLRWFREQAGDPNLKILV
GILPLATDRHATFLHNEVPGIIIPEEIKIRMRKAGDKSAKEGIKIAVELIDAMKAELQGV
YLMPAFNRFDYVSEIIETVKKKTQP
>A0A2U2AVM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia maris|TrEMBL
MTQLPDPDPTDGGRHPSIVERIATSTTPRVPFSVEFYPPRDEAAEERLWRAASVFSELGA
AFVSVTYGAGGSTRDRTVRVVERIVRETDLVPIAHLTAVGHTVAELADMIRMYGEVGVSN
ILALRGDPPGDPLGEWTAHPEGLRYAEELVRLIHEVGDFHVGVASFPEGHYRARDLDHDT
EVLVGKLRAGAEYSITQMFWDVEHYLRLRDRAVAADPEQGDKPIIPGLMPVTSLRQVKRM
VELSGCALPDDLAERLRTAAGDGPEENREAVREVGIDLTTRMCERLIAEGVPCLHFNTLN
FSRATREVLTNLSMAPAPGVAASRI
>A0A4R9AJZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium ruanii|TrEMBL
MSACNARPAFSFEVYPPKSVAAAAALTRTIDHLAAAGPEFISVTYGANGSSRDSSLDVLR
YIKDHTTVDAMAHLTCVGSSHAEASRLIRQFLDAGIRSFLAIRGDAPQGAIEGDTSFLGD
LHSAGELVQLIHRVQTERVPYIETVIPGLPAARGVKTERSKVRIGVAAFPNGHPNSRSVT
QDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVFFPILPGIMPVTSPNRLRRI
LQLSGEKLPAALSIELEVEPTEEGQRQIGIDHAVRLGQDVLAGGAPGLHLYAFNQHETVL
SVLEGCGALPVPAAMP
>A0A4P7SS82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. PAMC25564|TrEMBL
MSPPSLIDTHPNLAGAAPVALSYELFPPRSAAAAESLWTTIGELETTDPDYVSVTYGASG
SNRNTAVELINRLVQETTLRPLAHLTCVGNSPEELAEIIGELLDVGVRGILALRGDRPKD
GGTPPEGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTRQYADLLARARRAGVTIPIIPGVMPLTSIRRLTRLGELTGVE
PTPELMGRLAGADTDAERTRIGVNATVDLANAALDAGAPGIHLYTFNEHAAALEVLDKLA
LPRPHRTLPNASRRTASRIRLAS
>A0A1G1EDC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium RIFCSPLOWO2_12_FULL_47_7|TrEMBL
MKIIDLLRPMRPSYSFEFFPPKDNDGFNLLFETIERFKKWNPNYVSVTYGAGGSTRTRTI
DLVCRIKKAIGIESMAHLTCAGSPAEEIQSVLDTLRDQGIENVLALRGDPPQGEKEFAKP
QGGFGYANELVEFIRKKNYRFCVGVAGYPEGHLECPDKNRDLENLKRKVEAGADFIITQL
FFDNRHYFEFVDRARKIGIGIPIIPGIMPIVNLGQIKRFVKMCGATIPTDLISRLEKVQE
DNDAVAKIGIEHASEQCEELLSNGAPGIHFYTLNRSNSTVQILESIKSQVN
>A0A434STU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1A.F.Ca.IN.020.06.1.1|TrEMBL
MSIRHQRDENPAGVHLPLDHLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVF
LGAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRNFMQKARDLGHTEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIAGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>H5XDS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora cyanea NA-134|TrEMBL
MRRVVDRLASARCPTFSVEFFPPRDEADEAVLWRSIRELEPLDPAYMSITYGAGGSSREG
TIRNIARVATDTTLVPMAHLTAVNHSVSELRHVIGHFAAVGVRNILALRGDPPGDPMGEW
VAHPQGLSYAEELVRLVRELGDFCVGVSAFPYGHPRSADLETDTRYLVRKLNAGADFAIA
QLFFEAEDFLRLRDRVAAAGSDALMLPGIMPLTTPRTWHKTIELSGATPPRWLSERLEPL
TGDPKAFRAEGLDTITELCERLLAEGVPELHFYTFNRSKATRELVDRLGLRSPRAEPAAA
ARW
>A0A1I4SD60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriella xinjiangensis|TrEMBL
MKVTEHIERANGKTLFSVEILPPLKGQDVNCTFKTLDPLVELQPAFIDVTYHRQEFIYKQ
KENGLLKRYQVRKRPGTVAICAAIQNHYKVDAIPHLICGGFTKEDTEDALIDLNFLGIDN
LLVLRGDPIKTEKSFVPESGGHAYASELIEQVTALNTGNYLDDDLQESHKMDFCIGVAGY
PEKHFESPNLGMDMYYLKKKVELGADYIVTQMFFDNQKYFDFVKKCREMDINIPIIPGIK
PLTTFNHLTSIPQNFYIDLPESLAMEVLKAKDKEAIKEIGLEWCINQCKELKAFGVPGLH
FYTMSNSSNTKKVAEAVF
>A0A4R4JCW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus khanii subsp. guanajuatensis|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEKTLWKSIGRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELCEIARDYWNNGIRHIVALRGD
LPDNSEKPKMYGADLVELLKKEADFDISVAAYPEVHPEAKNSQADLICLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIEVEIVPGILPVSNFRQLKRFATMTNVRIPSWMTRMFE
GLDDDPESSNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A1Z8ZQZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium TMED86|TrEMBL
MAILSLLKAPKPTLSFEFFPPKDDAGADDLLKTVDDLGKLDPAFVSVTYGAGGTTRGRTR
SLVQRIMKEASVPTVPHLTCIGHSEDEMSEILDHYSKDQVSTILALRGDPPRNEPNYDRS
KDDFKFAADLVKFIKNHHHPIEIGVAGFPEGHPATQNRLKEMEYFKAKVDEGADYICTQL
FFDNHDFLDYRDRCTLEGIDLPIVAGIMPITTISGMKRMAELAEGSRFPATLLQALNTAG
NDAKAIRQAGVQYAINQCQELIDEGVSGLHLYTLNKSNATLTIANSLEF
>A0A358M1H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp|TrEMBL
MNVLDLINSARVSGRTRFAFELLPPLKGDSKQSVFQAIEPLMEFDPAYINVTCHREGIKQ
TRRPDGSTEWHVVRRRPGTVGISAAIRDRYKVEVVPHLICGGQSKYDIEDALIDMDFLDL
HNVLALRGDRSQNERVFMPHPQGHAHAEGLVRQIAAMNRGEFVDGEVEECHHSRFSIGVA
GYPETHAEAASPETDIAALKAKIDAGAEYIVTQLFYDNGRFFDFVKRCREAGIGVPIIPG
IKPLSTVRHLRILPETFGCRLPAELVAEVERHADDPKAVREIGTEWAIAQSRELMRAGVP
VLHYYPMGKA
>A0A502YH86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-6-6|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKSDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVGRILKETSLTPAAHMTCVDAPRPQVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVA
GSAAA
>U1N5P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloquadratum sp. J07HQX50|TrEMBL
MSLGAVSQATNDGVSHLLADPRFELMPFDSFESEIEALPTGSAIAITTSPQLGIESTVDR
AELAASMGYEVVPHIAARYVNGDDQLRDIARRLTGAGITDMFVPGGDKEEPAGSYESALD
LLEALDDMPYSFDEIGITGYPEGHDFISDKELTRIMNRKAPYATYIVTQLCYNHEAILEW
ISDIRDQGIELPVEIGIPGVMNYAKLLKISRKVGVGDSIKFLRKTSGIVDTVKRFVGSRG
VYKPDDLIDGLAPYYDDDEYNIDGVHIYTFNQTPDVESWRQSRVTQK
>A0A7G6WYQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella qitaiheensis|TrEMBL
MAEGFELICEVEPPTRPDLKKVRHQIGVLSPIADAFLIPDNHIGRATVSSVAVANEVQGM
GARGIACLNSRDRNLLGFRRDLLTAAAYGVEQFLFVHGDEPTAGARTSQLTVRTMIEEAR
ATSFPGIAPFQVGAATRLRPVPAWKAEADFLYVQVSYSLEDLLRWRDSITVDIPVYAGVM
VLASAKMAHNLAALPQLTIPDTLIASVEQDPDAGIDAACDHILQIRASGAFDGVHLIPVS
RYRQVAARLERDL
>A0A6L6FUR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia sp. wls1919|TrEMBL
THSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGDLPPGSGKPE
MYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRAITQFFFDVE
SYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFDGLDDDAETR
KLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>R9LSW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerotruncus sp. G3(2012)|TrEMBL
MRHAFQAPLWFDGAFGTYYFSLTGDETPCELANLKNPALVGQIHREYLKAGATALKTNTF
AANPGTLPDPEQLGTVLQAGLEIAQKAAAEHGAEVFADIGGISATDAEQFYLTVAERFLD
LGVTSFLFETLPSYEELVPALKRIREREPEAKIVVSFAVSQDGYTRRGLSHRALAGIAAA
DGYADAVGFNCVCGPSHMVSLVKSLGEIGCPIIAMPNAGYPSSLNGRVIFEDNAGYFATR
MVELYQAGVDLLGGCCGTTPRHIAQAVRAVCSVTRPERLTAVSEKTVASQVLPHGGKGKK
VIAVELAPPQDCDCSFLLSAAGELKSCGADMITVSDSPLSRARADSLMIAAKIRREVGIE
VLPHLCCRDKNHIALKAGILGAALEGINRVLVITGDPPVQSNMRNPGVFSFNSFDLISFI
ASMNTDLFSGRPFLIGGALNVNAANFPVELERARKKIARGAGMLFSQPIFSEQAVKNFLL
ASRELDCALFAGILPVAGYRNALFLVNEVSGIEIPDAVMQSLKDKTPAQAAEISIAYSAG
ILEQVYDAADGFYIMTPLKRVDIVRGLIERIHRREEQEESK
>A0A7C1S2R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantimonas coralicida|TrEMBL
MSRPNPLSTSGIDVSFEFFPPKTEKMEENLWRAIERLAPLGPSFVSVTYGAGGSTRERTH
QTIERLLKETRLTPAAHLTCVDATKEEVDAVVRQYWETGVRHFVALRGDSQAGVGGEYVA
HKDGYRNAVELVAGLKAFADFEISVAAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNDTFERYVERVRRAGIYIPIVPGIVPIHDFTKVARFSQATGASIPAWLAARFEGLED
DEQTRSHVAAAVCADQVLDLQKRGISDFHFYTMNRADLVYSICHILGLRADEASAPAGSA
SEAAAA
>A0A7J9XNR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MRAEGNGRGGGPEGGRLSRAIADGRFAVTAEIGPPRGADAEAIRRKARLLAGWVDAANIT
DNQSAHVRLSSFAGSVLALAEGVEPVMQVTCRDRNRIGLQSDLVSAAAVGIPNVLLLTGD
HPCFGDHADAKPVFDMDSVALVWTARSMRDHGRLLSGRSLEPRPDWLIGAVENPFSPPER
FRARRLGKKIAAGAQFAQTQFVFDIERFEHWLAQVRDLGLDRRCKILAGVGPVRSLRALD
YIRTQVPGIHVPEPVVRRLRGVPSDRVAAEGMRICVETVKRLKEIPGVGGVHVMAFGYER
AVPEILERAGLAPHRQPAPMGQPAPMGQPAPMGQPASPEGSGRAR
>A0A658JW63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. 1XD8-22|TrEMBL
MMDIRDELNRGVLLFDGSMGTYYASLYPDGERVESANRQHPGRVRAIHTAYLEAGARALK
TNTFSPFDVEGETLAQTLEAGYTLACEAAKPYDAAVFADLGPSAQSIGDCLRAADCFLSL
GAENFLFETFSDFAALDRVASYIKSKRPSAFVLTSFASNPDGVTRHGLSAAALLRQADAC
AEIDAAGFNCMSGPSHLLRLTESLQTLPRLLSVMPNAGYPAIVRGRTVYEGTPGYFAERM
AALTAAGAKILGGCCGTTPEFIRETRKALDTQRPAPKSVIASVQSRITLTERKEGRNRLA
EKLDAGQRIAAVELDPPVDADVSGFLTGARRLVEAGADTITIADCPIARPRVDSCMLAAK
LRRELGIDPIPHMTCRDRNVNATRALLLGLSIEEVHNVLVVTGDPVPSAERDEVKSVFSF
HSAILADYIRKLGSENAVVPFRVFGALNVNAANFDAELKKALRKRDAGVCGFLTQPVMSG
QAFENLQRAHEEMPEMKLLGGVIPVVSERNALFMNNEVSGIEVPEDIVRRYHGLGREAAE
ALAVELSVGFARRMEPFTAGWYFMTPFQRVSLIERILHALRG
>A0A7X6DNI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Manganitrophus noduliformans|TrEMBL
MKTLRDALESGEFILTAECLPPKGTDIAEFCSHARRLLGKVHAVNVNDNPAATLHASPLA
LSKVLLDMGHDPICQITGRDRNRLAIQSDLLGLHILDIRNVLCLTGDDITLGNQKEGKAV
FDLESVEILQVVRSLNEGKEMTGKPIQGATALLPGAAVSPEAEPLEPALMQFGKKVEAGA
RFFQTQAVFQPDRFERFMAQARKSNVNILAGVLLLRSLKMARYVTEHLGIFVPERFVQKL
ERAGKEGELEVGIEIALGLIEAIRGKCDGIHLMAIGAEEQIPVILERAGLLPKGPGLKKA
AGGADG
>A0A3R9LGS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus australis|TrEMBL
MTKQTPSLSFEVFPPNPEVGNAKLLRALENMQELAPHFISVTASNNKYNIKETTVALANH
IQNELSIPTIAHLPAIYLSKEKVADTLHELDQVGVHRILALRGDIIPGIEPLKDFRYATD
LIEFIKTEAPHFDVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVHHATKALFEHQPNLEVI
>A0A0Q6ZYK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Root1240|TrEMBL
MAQTARPNPADLKVSFEFFPPKSPDMADQLWQTVKALEPFQPDFVSVTYGAGGTTREPTL
ETVGRLIKDTSLATAAHLTCVAASRDEVRQVVDEFKARGVKHFVALRGDPQGGVGTRYTP
HPEGFENAADLVRGLRDMGEFEISVSAYPEKHPESANDAADIEMLKRKVDAGATRALTQF
FFDNDLFEQYLNRVRSAGITIPVVPGIMPIQNLAQLKRFASMCGASVPERLDQRFEGTDG
DAQARAEVAADVAAEQIADLAKRGIEEFHLYTMNRAPLTIATLERVGLAPKSRRNVSGAA
A
>A0A5E6NG51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Gammaproteobacteria bacterium|TrEMBL
MPYKYAIISVFLPAFRMPMKTSFEFFPPRTAKGKQTLHQVRQELSSLNPEYFSVTFGALG
TTQEVTLETVLDIQKNDTVAAAPHLSCIGSKKEIIIELLDQYKAANINRLVALRGDIPSG
VRDIGDFHYANELVEFVKSQYNHHFHIEVAAYPEMHPESKNRLTDLQHFADKVKAGADGA
ITQYFYDADAYFKFVDATEKLGINIPITPGIMPITNYTQLVRFSKMCGAKIPHWILKKLE
LYQDDFDSLSAFGLEVVTNLCQTLKAQGVNNFHFYSMNRSQPSLEIAKHL
>A0A5C8HMJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium mitrae|TrEMBL
MTHEIATLPFSFELYPPRTDTSVQALHRTIDELAAVNPQFISVTYGAGGSSGGRSLEVLT
YIREHTGVDPLAHLTCVGNTYAGATALIREFLDAGISSFLALRGDPPAGTREEDIYLGDL
ESSAQLVQLIDRVQAERVPFRQSDVPGIPGAARVDRRSRVNIAVAAFPNGHPRSRHAREH
IDALLAKQAAGATLAITQLFFHADAYLAFVERARQAGVTIPILPGIMPITNPARLNRVLE
LSGEELPSELAIALEIEPTAEGQRDLGIEYAANLARAVADGGAPGIHLYAFNNHDTVLAV
LREAGILIQKENVR
>A0A4R2HVC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2572|TrEMBL
MANGLPSTLPGGTPTIRELLASGARSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGAGVRNMLALR
GDPPGGPNQPWVAHPEGMNHAIELVELIRSLGDFCVGVAAFPDKHPEATSLEADAQVLAA
KAAAGADYAITQMFFGADDYFRLVERATALGCDIPVLPGVMPVTNIKQIQRMAELTGMAL
PAAVTDRLLAVEDDPGAVRAVGIEIATELCEQLLAGGAPGIHFITLNRSTATRQVFLNLR
STVVS
>A0A0Q6ZGA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Root1240|TrEMBL
MAHIDENPLGPHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDQSKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMAKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDSVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGVLKGRKPWKREHVRSDDMAAERMREIGADPVQDQQELAGRAA
HPQAH
>A0A2E6HNH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Legionellales bacterium|TrEMBL
MESQKKYSPXFSFECYSPKTPEAIANLQNAQLELASLKPDFFSVTYGAGGSTRNMTFETV
LDIREKTGFESVPHISCIGNYNDEINAMLQSYIDNDIKQIVVLRGDLPSGTVGYGQYQHA
NELVEXIRKQTGDHFXIEVAAYPEFHPQAASPKVDIDNFKRKVDAGANGAITQYFFNPFS
YYRFIDHCEKLNINIPIVAGVMPITNCTQLVRFSEGCGAEIPRWVLKQLQGFGDDRESIF
KFGVDVVTELCDQLLSXGAPGLHFFTMNKSAASIAIWKNLGLDKRTIK
>U4S9L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaesserella parasuis D74|TrEMBL
MSYAKEIDLLNQSVADLNGKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERNRTHSIVKTIQQETGIVAAPHLTGIDATPDELRAIAKDYWDSGIRHIVALRGDEP
TGYAKKPFYASDLVKLLKEVADFEISVAAYPEVHPEAKSAQSDLLYLKQKIDAGASRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMAKMYQGL
DDDQTTRNLVGASIAMDMVKILSKEGVKDFHFYTLNRSELSYAICHTLGVRPE
>A0A2G2DTN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotalea sp|TrEMBL
MEIRTASKLEKILKNGHMAVSSECGPPRSSDAKGIIEKAHLIKDHVDCINVTDNQTSVTR
LCSLAACIHLKHEGLEPVLQMVVRDRNRIALQSDILGAASFGINNMLCLSGDHQSFGDHP
SAQNVFDLDSIQLIQTSRYMRDEGKFLGGGDIEKPPNMFIGAAANPFADPFKIRVPRLAK
KIAAGAEFIQTQCVYNLEKFEKWMEAVVERGLHEKVFIMPGITPMRSVAMAKYMAKSVPG
MDVPKDVIARLSGVAKDKQADEGITIAVEAIERLKQIKGVAGFHIMAIEWEEKVPEIVER
SGLYPRPIVD
>A0A2W5F6W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudopedobacter saltans|TrEMBL
MKITEHIAKAKDTLLSYEILPPLKGKDIGSIYKHLDPLMEYKPSWINVTYHRTESVFKKR
PDGSIEKTKMRKRPGTVGICAALENHYGVDATPHIICGGFSKNDTEDALIDLNFLGIDNI
LALRGDAAKSDGEFIPEPNGHRYAIDLIKQVANLNKGIYLEEDEVTDGIATNFCIGVAGY
PEMHFEASNMKTDLAYLKAKVDAGAEYIMTQMFFDNQKFFDFVKNCRAMGINVPIIPGLK
PITRKKQLSVLPKIFNVEIPRELSNAILQTENDMDAEKIGIEWLTQQSKALKAFGVPVLH
YYTLGKPETIRNVVKEIF
>A0A421DR78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brenneria alni|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMETTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKAIKERTGLEAAPHLTCIDASREQLREIAQDYWQSGIRHIVALRGD
LPEGDGKPEMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLQRFATMTNVRVPNWMTAMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAIG
>A0A4R9RYN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.230.01.1.1|TrEMBL
MNARQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTERLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A6N3WMF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus icigianus|TrEMBL
MGLLDELKQRVLIADGAMGTLLYSHGVDRCFEELNLSKPEDIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGRAYVLGTIGGLRTLNKSAVPLDEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYYMLQSLEEVPLPTHAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLLGGCCGTTPNHIEAMARALQDRTPVTEKTVKRRAVPVS
VQSDAPSAATPLPELVRARRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLA
TPRISNAAVATIIKERLGVRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVER
MEKKIQCGAHYFLTQPIYSEEKIVAVYEATKHLDAPIYIGIMPLVSARNAEFLHHEVPGI
TLSDDIRARMAACGDDPVRAAREGIAIAKALIDAAFDLFHGIYFITPFLRYDMTVELVRY
IHEKEAAAKERKVVHG
>A0A7U5BWS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis subsp. globigii|TrEMBL
MGLLEDLKHQVLIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHEAYVQAGAHIIQTN
TYGANYIKLSRHGLEDETKKINKEAVKIARASSGGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAQEVLKIARKETDLPIVLNVSMHEQGVLQDGSP
LSEALRSLVGLGADVTGINCRLGPYHMIEALTEVPIFDDAFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSAIEFRKQGARIIGGCCGTTPSHIRAMADAVGGLEPITEKEVKVRAQETIS
IQHERTEPGLDEIASQKRSIIVELDPPKKLNFEKFLSAASELKEAGIEALTLADNSLATP
RISNVACGALLKQQLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLNDILAVTGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGRKTNFSVAGAFNPNVRHLDKAVKRLE
KKIDCGADYFISQPVYSEQQLVDIHNETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIREKMALAGEDKQKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
KKDEKRENVFLH
>A0A1Q8XIJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces oris|TrEMBL
MHDNELTGPTAAAGSRGETLSSAETGTARRLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPAGGLTGGGRQGSAHEPEAGRCEAAPRVRAVQEQTNPSECVLAH
VLDSSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRAEDVAGELRH
ADDLVRVIREVEADFFGDGRRHVTIAVAAYPATNDHIEAIEVLAAKQAAGADMAITQVFY
DAADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPPGLRSSLGSASGAT
LVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDA
VDRGYLQATPGRGPSFLRRGSARATVSSHHPVSPLTTITKENA
>A0A2H0PD23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG11_big_fil_rev_8_21_14_0_20_47_16|TrEMBL
MTNFLEQLNDRVLLADGAMGTEIYKRGVFINRCYDELNLTAPDIIRGIHEDYVRAGADII
ETNTFLANPIHLQSYGLETKTKEIIAAGVKLAREAVGKKDVFVAGAMGPLVRQIEPIGRV
TLDEAREAFKIQAGALIDSGVDLIILETFQNLRELKLAYDVIRSLSKLPVIAQFAFVDNS
AEKPEDVVKAIESWGVDVAGTNCANGPQMTLSIVERMRSVSRMKLSAMSNAGLPQVVEGR
TMYLATPEYMAEYARRMVQKGANIVGGCCGTTPADIAEMRNFLKSIAPTPIVSIKPVDKQ
AVDIQPVPLAEKSAFGAVLGKKFAVSVELDPPHGLSPGKTIEAAKFLYDNGIDAINIADG
PRAIARMSPMALASMIKQQVGIETIVHYCCRDRNLLGMQMDLIGANAMGLNNVLIITGDP
PKMGNYPSATAVFDVDAIGLLHFANGLNHGRDLAGKSLGAPTKLVLGCGCNPGAVNLDLE
VERYAKKVEAGAEYVFSQPVYDVAILEEFLKRTAHVKPIPFFVGVLPLASLKNAEFFHNE
VPGMQIPPAIMKRMAAKESKEAQQSEGLAIAQEALKAASKIDRVQGTYIFPPFGNYRAVM
DLLDVL
>M7U459|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon SCGC AB-539-N05|TrEMBL
MKYRSNLERVLSEGKFVVTAEIGPPKGSDPKKIEQKGKILRGYANAFNITDNQTAVVRMS
SIAGCYILLKMGLEPIMQMNCRDRNRIALQSDVLGASANGVKNIFCITGDHQSFGNHPAS
KGVYDVDSVQLIQIIKNMRDNGVFESGDTILSGNPDVFIGAAANPFSDPCEFRVDRLEKK
VEAGAEFIQTQSVFNLDKFNMWVDEVRSRGLDKTIRILAGVTPLKSLKMTERMKFYIPGV
DVPDKIYNRMKNAVDPKKEGYKIAVETIRELKNVKGIHGIHLTAIFWEDIIPSLVKETGL
YPG
>A0A8J7U4G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acanthopleuribacter pedis|TrEMBL
MRKDFRTLLSDGKPILLDGGIGTELYDKGVFINQCFDYVNISNPEWVKQVHESYLAAGSD
VIETNTFGANFMRLKHFGLEGDLESINREGVRLAREVAGDNKYVAGSMGPLGIKIEPYGP
TSFEETRAIYRQQAQVLEEEGVDLYILETFSRMAELSEAVAGVREVSDKAIIALLTVNDH
GQTLYGTDPVYLVPELEKLDIDVVGLNCSVGPRLIYDALEKMVKYSSKPVCAMPNAGNPK
SIDGRNIYLCTPEYMATYAKRFLKLGVRVIGGCCGTSPEHIKSIARAVGQSMSSDVKKKV
VAPGAPMEQVEAREVLPLAQRSRLGEKLAAGAFVFSVEVVPPKGCDPTRTLKRIQKLKDA
EIDAVNIPDGPRASSRMSPQILAILVENQIGIETILHYCCRDRNILGMQSDLLGGFAAGL
HNILAVTGDPPKLGDYPDATAVFDIDAIGLTNIINHLNLGRDIGGNDLSKPTAYATGVAL
NPTALNAVEEINRFHWKVKAGADFAITQPVFDTAQFLHFYEQVKHHQIPIIAGIWPLVSY
KNAEFMNNEVPGISIPESTLARMRATASSEEAKEVGLQIALENVTQILPYIAGAQISAPM
GNVKFALRVVEGVRAMLKDRRPAAEAVPVPSR
>A0A8C0VFY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanistes caeruleus|TrEMBL
MLVHKRSKAPTSSWNRRPALLSHISCQLESFLRALTMVNETQHTCSASSSSRSDGGSSSG
SESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDKWFSLEFFPPRTANAAVNLISRFDR
MGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDITGHL
QKAKRLGLKNIMALRGDPSGEEWEEEVEGFNYAVDLVKHIRNEFDDYFDICVAGYPKGHP
EAESYEADLRHLKEKVFAGADFIITQLFFRPETFLKFMKDCQAIGITCPIIPGIFPIQGY
HSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRSYGVELAVSMCRELLDSGMVHGLHFYT
LNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWD
DFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVFTCYITGE
PNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGILTINSQPNINGKPSTDPIVGWGP
SGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWG
IFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLV
DNDFPLENCLWQVVEDTFELLNSPTQQ
>A0A7V6TA30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterales bacterium|TrEMBL
MPKINKFKESLLDKNTMSITWELVPGRGAREKAQEDVIINAEKASKGRKVHALTLTDNPG
GNPAISAEILAAEIVQMGIEPLVHFTCKDKNSNQIESLLYALDRVEVRNLLVMTGDYIYS
GFFGRARPVFDLEPMHVLTLLSAMNRGLEYDGPKGTKKHKPSEFFAGAVCSPFKKTEAEL
MAQYYKLKMKVAAGAKFIVSQIGFDARKIHELIQFVKVNNWDIPVVGNIYVLPYGTAKLM
SKNGIPGCVVTDKMLAELEKESKAPDKGRKARYLRAAKMYAIMKGMGYSGVHIGGHGTKY
EDIEYIIDKGEGLSKDWISLISEFDYPMPDGFYYFEKDEKTGLNSDRVTDRKGRALDTKV
ELIYPLSKIVHALMLEPGTLLWKPMRAIAKSIEDTVFEKPYHFIEHITKTILYDCKDCGD
CALPDLAYVCPMSQCPKNIRNGACGGSYDGWCEVYPGKKKCAYVRAYSRLKSCSKEHYLD
HDMIPPWNLNLNQTSSWINLYLGRDHNADKYGIERIDSKNNK
>A0A2S7KLY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureitalea marina|TrEMBL
MKVTEHLDKNQGKTLFSFEILPPLKGQNIQSIFENIDPLMEFNPPFIDVTYHREEYVYKE
LSNGLLEKHIVRKRPGTVGICAAIQNKYQVDAIPHILCGGFTREDTENFLIDLNFLGIDN
VMALRGDAVKTETYFTPEKDGHEYASQLVGQIIALNLGEYLDEEIQNQAKTDFCIGVAGY
PEKHMEAPNLDSDIHFLKKKIAKGASYVVTQMFFDNKCYFEFVDRCRKAGIDVPIIPGLK
PLATKKQLNLIPHRFNADLPEELIKEVIKCENNKEVRQVGIEWCIAQSKELMDNGVPVLH
YYSMGKSNNIRAIAQELF
>B1C618|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerofustis stercorihominis DSM 17244|TrEMBL
MKITEILKHDKPTLSFEVFPPKNEVNYKDVEKATGEIAKLKPDFMSITYGAGGGTSSYTV
NIAKEIQKEYAVPTLSHLTCMCSSKEDIKAQLKLLKDNDIENVLALRGDIPNDKSLMEKS
EYTHAVELIRDIKESGDFCIGGACYPDGHVECEHKADDIYFLKEKVDAGLDFLTTQMFFD
NNVLYNFLYRIREIGITVPVFAGIMPVTNGKQIKRITELSGTYLPTRFKAIVDKFGDDPA
AMKQAGIAYATEQIIDLLANDVRGIHVYSMNKPEIAEGIKNNLSNIL
>A0A3C0FU12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira sp|TrEMBL
GLISEGVTDFHFYTLNRAELTYAICHALGIRGPEQAAA
>A0A1R1LZ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Motiliproteus sp. MSK22-1|TrEMBL
MNTELLQKFSDPNQGIYFVGTTPPRASTDDMQMSQIAGKLLDRLSHLDYDGLIVYDIQDE
SARTDVPRPFPFVGTKDPRAYSQLLAEKSGRPMITYKSVSQRNREEFQSWLDDAWHQYGI
RNLVLVGSPSQDADIKLSLNEAYATLEERDDNFALGGVTIAERHAKKGNEHQRLHGKATK
GCRYFISQAVYDADATIELLTSYGKQCQAEGTAPQRVILTFTPCGSSKTLEFMQWLGISV
PSDISDKIIESNNPLAESIRVCRSNLNRILDACLPLGIPLGLNIESLTNRKDEIEASIRL
FKLLKATLEERLQNH
>A0A4V5PXN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. ASW18X|TrEMBL
MKVTEHIANAKGETLFSFEIVPPVKGKNIQDLYDNIDPLMEFKPPFIDVTTSREEYVYIE
KNGLLEKKVTRMRPGTVGICASLQYKYNVDTVPHVLCGGFTKEETEYMLVDCQYLGIDNV
MALRGDAMKGEQYFSPCEGGHSYAKGLVEQIAALNQGKYLIDELKMEHTPNFCIGVAGYP
EKHLEAPSLQNDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVDAARAMGITIPIIPGIKP
LAVQKHLRLLPQVFWVNLPEDLIDAVEACPDNKAVRQVGIEWAIQQSKELKDAGVPVLHY
YSMGKSSNIKAIAAALF
>A0A171BBN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planomonospora sphaerica|TrEMBL
MALGRPSILPDRVPTVRELLAAGGRSFSFEFFPPKNAEGERQLWRAIRELESLRPTFVSV
TYGAGGGTRDRTVEIVERIAHETTLTPVAHFTAVDHSIRELRHLIGRFAGAGVRNILAVR
GDPPGDPTGEWVRHPEGVLYAEDLVRLIRQSGDFCVGVAAFPYKHPRSVSVEADTEYFVR
KCRAGADYAITQMFFRAEDYLRLRDRVAARGCDTPIIPGIMPVTQMSTIARSEQLSGAPF
PPEVAARFEAVSDDPAAVRALGIEHAAELCRTLLDEGAPGIHFITFNRSSATREVFRALD
HAAADAAPDHVPETASLTG
>A0A2T5JZC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira sp. Nsp2|TrEMBL
MESQKKFAPTFSFEFFPPQTAEGIEKLRATRRQLAQLNPKFFSVTFGAGGSTRDRTLETV
LEIQAEGYTVAPHLSCIGATSDNIRSMLRQYRDRGVRHIVALRGDLPSGMAQGGEFLYAR
ELVDFIRAEFGDTFHIEVAAYPEYHPQADSAQEDLRHFKQKVEAGADSAITQYFYNADAY
FSFVEACEAMGINIPIVPGIMPINKFSQLARFSDACGAEIPRWIRKRLEGYADDSASIRA
FGLDIVTDVCDRLLSGGAPGLHFYTLNSAGLTSTIWQRLGL
>A0A1F4UCK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-3 bacterium RBG_13_43_14|TrEMBL
MLRDQMNKRQIITVEILVPTGMAFEKLCRAVEPLKDYIDAFNIPSNPLGRLRPDAMCSAH
LIQEKTGVEAIPHFVARHFTSLGFESHLLGAAALDIKNILCVTGDSPEEGRSTFELNAVR
LISMARGFKNGLTSARRSIEPIDFCISASFNPNVPNVHGEFLKVGEKVNAGAEVFFTQPV
FDPELFLKVIGGFKKYPGIKIIAGLSYLYTKKRAFALMKYLGIPYDYIKEIEEIDETELL
LRTAGQIRNAVDGFYIIPIAKYDNALTLVKNLRNICR
>A0A368EXA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MAHATPTTESAKRLVEGYSLEITGKEKDVVGLTEAASLIPAGTKVNVTFLGNEDLPMRVA
AAKAVKELGFVPVPHISARRIASQAQLEEFLSALAEIGATEHVFAVGGDPATPEGPYPDA
LTMIRSGVLQQYGVKEVSIAGYPEGHPDIPTDVLWQHLEDKSAALKDAGLDAVILTQFSF
DTDPVMAWIKCVRDRGIDTQIRLGTPGPAGIKRLISFASRFGVGANAMIVKKYGFSLTNL
MGSAGPDKFVSDLAALFDADPSVGAVKLHMYTFGGLEATATWAHDFIAK
>A0A4Q4TP72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus ibericus|TrEMBL
MEKITDKIAALPADSNYFSLEFFPPKTAMGFANLRDRLDRMARALRPLFVNVTWGAGGST
ATKSLELAEICQRELSLTTCLHLTCTNMSRRMIDTALEDAKALGIRNILALRGDPPRAAE
YQDPNSEPGDAIDESFKWAVDLVRYIKKTHGDYFCIGVAAYPEGHADESHPRGQSLEHDL
PYLVEKTLAGADFIMTQLFFDAEAYERFERTLREHPSGAFKTLPIIPGLMPIQSYQMIKR
TTKLSHAKIPEPISARLDAVKQDDEKVKNVGVDILSEIVERVKEIKSRTPGPKGFHFYTL
NLEKAVSFILERTKLIPPSTPEEDEAVADVLAPRVPKLEVNGSTHEPPVPTKHRQRRESI
ARSDVEASIHELPVPAQDRVRRQSTVGSEPRNRVIVSEESPSHPEYEATQAEASILAEPI
NTRANTLAISEGEGTLGREATWDDFPNGRWGDARSPAYGEIDGYGPSLHVTNAQAITLWG
YPKKPEDISDLFVRHLKGELSAIPWSEEEFNAETATITDQLLALNSKGWWTVASQPAVNG
LPSSDPTFGWGPQQGFVFQKAFVEFFLPSAEWRVLLEKLQSAEVQDTVCWYAANAAGDFV
SSDLTGGLAGEAAKEPSTNAVTWGVFPGKEIITPTIIEEVSFRAWSDEAFGIFAEWAKVY
GKGSESAALLEAVRADVWLVNIIHHDYVDTDALWNLLLN
>A0A1J5PB21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MSRLSELVSDGLSTIFTAEFPSIDGGGMAVVAKHSARLLPWFDAVNATDNPAAHAHASSL
AVSIAMKSHGLEPIMQVVCRDKNRLAIQADIVGASLHGIENICLLTGDDVTAGDEPETKR
VFDIDGPQAIHVASALASGKYLSGRKLDPAPKLFIGAVENPAAPPFDYRISRVSKKVEAG
ATFLQLQIGYHPERLEQFCTGVNRAHPSLALLPTIVLVKGARPMNFMNEKVPGIDIPAET
IRRIESSSDQPEAAYLLALEQAKHALEQPGVRGLHITDFRHDESIDRLMSDLGRVRR
>A0A6I2LUV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. S-4012|TrEMBL
MSRPRLSFEFFPPRSLDASFRLWETVRELAPLDPAFVSVTYGAGGTTRQLTHEAVTTIGS
HYWVSVAAHLTCVEASREETMAIVDGYAKAGVREIVALRGDAPQGTDRFTPHADGFASSV
ELIEAIAARGDMQVRVGAYPEPHPDSADTAADVAWLKRKIDAGASSAITQFFFEADTFFR
FRDACADAGITAPIIPGILPIQSWEGAKRFAARCGTAVPAGLDEAFATARRDGREQLLAT
AICAELCDALIEGGVEDLHFYTLNRPEMTRDVCAALGILAAPRLEAVA
>A0A8H7C9V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agaricus bisporus var. burnettii|TrEMBL
MKISQKIQQQSKENKLWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
ELTSQMVKTCQSLIGIETCMHLTCTNMPIEKVDIALREAKASGCRNVLALRGDPPAGKEE
WEAIEGGFVHGIDLVRHIRKLYGDYFDIAIAGFPQQMLLPPEELEQEMMWLKEKIDAGCS
FIFTQMFYDVEIFIKWVHCVREHGITIPIIPGIAPIQTWNGFMRATSLAKTIIPQSFMDV
LEPIKNNDEQVRKLGIKLVADMCRRILAEPLGIQGLHFYTMNLEKGTKMLLEELNLVPRV
ETIKPLPWRQSLTPSRRAETIRPIFWANRAQSYVSRTENWDEYPNGRFGDSRSPAYGELD
GYGVSLKHTKDDALKLWGEPKTFADVTSLFTRFCTGELTALPWSDQKLETETSVIAKQLA
QMNDLGFLTINSQPAVNGARSDDKVFGWGPANGYVYQKAYLEFFVTPSLLDLLIPHIERD
SNITYYVINKAGDLRTNTHSDGPNAVTWGVFAGKEIIQPTIVEAISFMAWKDEAFELGKQ
WAALYEADSPSHKLIHELMETCLLVNVVHNDFHDTEAIFKPFLKAGAEFFAKTKPLTNGH
>A0A847BVR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacteraceae bacterium|TrEMBL
MLYKLLDNNEFNILLYGLTPPKVTHTKEDILAISQRQIDRLKGAPIDGIVMYDLQDEAER
TALKRPFPFLETIDPTEYVDRYLKSLQKPAIIYRAIGKYSHEETELWLINRNSTDSISVF
VGAASKNQKVQMSIKDAYVLCKKVAPNMKLGGIAIAERHSQKNDEDFRVIDKMKQGCSFF
ITQAVYDFNSAKKFLKDYAKRVEETKANAAPIIFTLTPCGSEKTLDFMKWLGIEIPSDIE
IALKEAPCMLQASVGHILEVYYRLYALGKELNIPIGCNVESVAIRKAEIEASIEMIYALR
GFMTNS
>T0Z3N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MPRAPEAGLHGDPDEGNGMINVSFEFFPPGDAAMEATLWRSVERLRPLAPKFV
>A0A7L2W6H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandion haliaetus|TrEMBL
MVNETQHTCSVSSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEIDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRYLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VEQAVSVCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLDNCLWQVVDDTFELLN
>A0A6P3XGK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dinoponera quadriceps|TrEMBL
MRNFVLAKKRDTDRNDIEDDSPTTCNLRTENRHREIVDLRRSLRDKISKHEIFYSFEIVS
RKESGTSYQRLLAEMDKYSPLFYALTWHVNEGVSGNKNYAPLEILKNLPNNTLLHLAAKG
LRRDEVVSILEKALTLEIVNIFALQGDSSSGDGDFVHASELVAFIREHFGDAFCVCVAGY
PQMHPKSASKELDLHYLKTKVEAGADFIITQVIFESQVFIDFVKDCREIGIQVPIIPGIF
TPTDYECLEMMERVCKLDIPGKIKDDLARMRGEDTMMRKFVLELTAQIITDVIGSGATCG
FHLFTLNRLSLLTEICGHINSCKQMT
>F3GDG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. pisi str. 1704B|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A8H7WPW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cadophora sp. M221|TrEMBL
MHIKDMLAEAERSGQPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVSVAQSQHGLETCMHLTCTDMGQGAVDAALKDAYKAGCTNILALRGDPPREKEK
WVATEGGFHYAKDLVKHIRETYGNHFDIGVAGYPEGCDDQDDPELLLEHLKQKVDAGATF
IVTQMFYDAENFIDWVHKVRAKGITIPIVPGIMPINTYASFLRRCNHMGCSIPPEWSATL
EEVKNDDAAVRNIGTGLVAEMCRKLLAAGIHHLHFYTMNLAQATRMLLDELNLTPSEQRP
LKQALPWRQSLGLGRREEDVRPIFWKNRNKSYVTRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNRKLWGEPKSIKDIADIFVKYLQNGVDSLPWSEAPITSEADSIKSDLIA
LNERGMLTINSQPAVNGAKSSDPVYGWGPSNGYVYQKAYLELLVSPTLMIQLIARIELNH
DLTYYAVNRAGELKTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGLDW
AHCYSALSPSRQLIENLMDTWYLVNIVHNDFHNTHGLFPLFEGLQVKDIDVPFPAATNGV
ETNGVKGTTEAPGVENIPLMNGTSATH
>A0A1D2NAR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orchesella cincta|TrEMBL
MASLNYSGLDTMLHMTSAGATIADIDRHLAKAKNMGIRNILALRGDRLEDGNPSDFEYAT
MLVKHIRKKYGDYFVIGVAGYPSGHPEANSYEEDLKYLKEKIDAGADFIITQLFFKPEVF
LKFVNDCREIGIRVPIIPGVMPIQSYDSLRHIVKLSKLEVPQEIVEIVEPLKHNDEAIQN
YGIYQACEMIKAMFQSGVAPGVHFYTLNREVATMSIIKQLGLWNCQPQRPLPWKVVPSFR
RCQEEIRPIFWSTRPNAYIHRTSHWDDFPNGRWGSSESPAFGDLRDYYLFYLKSKSTKEE
LLEMWGHSVDSYQDVWDVFYHYLMGLPNKNGVKITKIPWNDEELCPETAVISERLACLNK
RGILTINSQPNVNGVDSTDPVHGWGTQGGYIYKKAYLEFFVSGRRMQNLKHILTQYSQIN
YHIINKNGRFNFTNAHRQCPIAVTWGVFPGREIIQPTVVDPESFLVWKDEAFGLWTEQWA
KLYPEGSKSRQIIESIANNYYLVNLVDNDFPKETVLWEVLDKLLSCDDGNHEEDYESTDE
SLSCSSVSDEVDSQLQKLSV
>A0A2T5CEI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfonatronum sp. SC1|TrEMBL
MRIKNLLEQPERSKISLEFFPPKDRALWPKFFDTAQRLRALDPLFVSVTYGAGGSTQAAT
LEIVTTLKRDFALEPMAHLTCVGASTQVLRSFLDDLVRAEVTNVMALRGDPPQGETSFVP
SNDGFRYASDLVRFISAEYPSMGIGVAGYPEGHPEAVGLNEDMDFLKMKLDLGGDFAVTQ
LFFDNAIYWKFVQLAREAGITKPILPGIMPIFSLKFIQRITSMCGATLPAAFLKDLEQAE
ARGGDAAVQEVGMAYAAAQIQDLLDNGAPGVHLYTMNRSDGCLRIMEQVHR
>C3JJ66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus erythropolis SK121|TrEMBL
MTFDPVRGRSSEGWATRTPSIVDRIASSTGSRIPFSVEFSPPRDADAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSTEELRAMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPEGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
YDTKYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVSAYDAEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGPDENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTPDTSVGTAQAV
>A0A5C6W8J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ISID311|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWVKHPDGVAYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVD
KCRAGADFAITQMFFYPEDYFRLRDRVTAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A484HPV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacteraceae bacterium|TrEMBL
MPSSFKKALDSGKFVVTCELAPPKGTNLDKFIHHIDMLKDQVDAMNVTDHQSSVMRFPSL
GGAIMVKERGGEPILQMTCRDRNRLALQADLLFAASRGVENVLCLTGDSVMLGDHKEARG
VFDLDSSQLVAAIRRLERGKDLGGSDLDGGVSMCAGAIVTPEAEPLEPQLIKYEKKIEAG
AEFIQTQAVYDMEKLQSFMAYSRRFPVKVLAGVILLTSAPMARFMNKNIAGVNVPADLVD
EMAAAPKGGALAKGIDIAGRMIRQIREEKVCDGVHIMAIGREELVPDIMKAAGI
>R7JAV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides sp. CAG:409|TrEMBL
MNVVDLINSHQGTAFTFEILPPLKGNSIQKVYQVIDKLREFDPKYINITSHHSEYIYKPQ
PDGSLRKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVHNL
LLLRGDIKTLEVEQHPEQYHEHATDLQQQVNRFNEGIALDGSRIEGIDTPFSYGMACYPE
KHEEAPNMDSDIYYLKEKVKNGASYLVTQMFFDNEKFYAFEDRCRKEGINVPIIPGIKPI
VFRNQLTVLPRVFRSDIPEPFAAELRKCKTDDEAKEVGVEWCIQQCKDLIAHGVPSLHFY
TMMASESVRRVAKEIY
>A0A2I1WBS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium coyleae|TrEMBL
MFEASPSTRLSASAPIDREGAPVIRRPRPKRQRTALSFEIIPPRPSDSVAKMDELIAGLA
AYNPDYVSVTSSRRSEWLEGTAAVISRIAETTDLRPIAHLACTAGTREELTEWIRTLIDA
GVRGFLALRGDLPETGMPEHHLQYATDLLNLIEEVQEEEAFRLAAGKLALSVACYPKGHE
ESRNFDHDLDVLLTKQRLGADFAITQLFFEAQDYLDFVEVARLAGVRIPLIPGIMPMTSL
KRVRRMGELSGLEVPEVVEKQLLEADDEYEAGMQLTANLAREILDAGTGGLHVYTHNNLA
VTRDFLDRIGIQ
>A0A484HI99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfobacteraceae bacterium|TrEMBL
MGLKEALGKKKFVVTSEIQSHVEQEPERLIESLKGVRGRVDGYSVSEVEIEGVVGDSIKT
CGLLKENRFDAIYQTTTRDKNRLELQKDLVGAHEAGVENLLVFTEDYRITGDSLQEMMFF
HVDAGKLSSVLEHITQGHAIDGKALDSKADFTLGSGVESGWGKNVPDLELKEMEEMTRIG
AGYFLTTPVFDLDKFEKFMKHANPFQVPVIAEVMILRTAGMGRFLNRHLRPGLVPDWVIK
KLARAKDREKASLELFADTIKGLKDLCQGAHIISIGGEERLSRYLDAAHLK
>A0A7W6H1T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter undariae|TrEMBL
MTTPAVSFEVFPPKSVDAAFKLWDTAQALAPLEPRFFSVTYGAGGTTRDLTHDAAHVLHR
TSKLPVSAHLTCVGASVAETMEIAEKFHAAGVTEIVALRGDPEGGASKFTPHPEGFKNSV
ELIEALALLDKFTIRVGAYPESHPDAVSQHANIQYLKRKFDAGADEALTQFFFETESFLR
FRDQCAAAGITKPIVPGIMPITNWNSARKFAAMCGTNIPEWMDEAYRAAERDGRTELLST
TLCTEMCSELVAEGVDALHFYTLNRPELTRNVCRALGVTPQSDLSNVA
>A0A6A4EB19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora rubi|TrEMBL
MKIIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMAEADIRKALDQAKAAGIRNILALRGDPVRGATS
FDECDRGFSHAVDLVRYMREHYGDHFCIGVAGYPEGHVESSDKKADVQYLKEKVDAGADF
VITQLFYDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTAFCNTFVPQEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRAAESMRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSSTSTPNERRAMWGEAPAAKEDIRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGVLSDDPMFGWGGLGGRVYQKAYVECFVSPENMKIIIENAAKK
PSVQYHAVNLNGHSYSNASKSAIAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEDGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSPATSP
>A0A7H8NU92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. NA06056|TrEMBL
MTAISFEFYPPKTDEQRTQLDRAAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAQDALLDLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VQRLGVQVPITPGIMPISNFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGAEVV
AKLCQRLIEGGAPGLHFYTLNLAKPTVSVLTLLRG
>A0A7W3RPC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces murinus|TrEMBL
MNPAVTAPAAVGTALLDDFSLEMTGKDVPALEEARGSIPQGTRINVTFLAGEDHATRLAA
ARAVRRLGFVPVPHISARRLTSSAALEEFLAGLAEDGTADNVFVVGGDPARPEGPYGDAL
AVLRTGLLERYGVRHIGISGYPEGHPAISGPALWSALTDKARAIGAGPFTGDVITQFGFD
ADPVLDWLAAVRARGIDLPVRIGVPGPAGIRRLVGYATRFGVTTSASVARKYGFSLTNLL
GTAGPDRFLHALGERYDPARHGVVKVHFYTFGGLRTTAEWVGGFRERTR
>A0A1L8ZH70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus obstructivus|TrEMBL
MNIVEKLKSSVLVADGAMGTLLYSYGKDTCYEEFNLSHPDEIINIHQAYIQAGAQVIQTN
TYGANYFKLSQYGLEEQVKAVNTEAVRIAKKAANKETIILGSFGGYRGIRKADITLSEIK
RSFREQLFHILNEGVDGILLETFYDVEELLAIVEIAKKESDLPVIAQFSLLEPGVLQNGM
ELREGLYRLEEMGADVIGLNCRLGPHHMIQSLEEIPLPKNAFLSAYPNASLLDYEDGRFV
FTNNATYFKDCAVQLVKQGVRLIGGCCGTTPEHIRAITEGIEGLVPITKKVVKPSKEKIE
LAITQVPTEPPLHEIVKGRTSIIVELDTPKHLQTERFIEGAKALKAVNIDAITMADNSLA
SPRISNVAMGTILKEQYNIRPLVHITCRDRNLIGLQSHLMGLDALGIDQVLAVTGDPSKI
GDFPGATSVYDVSSIDLIQMIKQFNEGLSYSGKSLRKKASFSVAAAFNPNVRNIDRAVGR
LERKIKSGADYFITQPLFSEEKIIEVYEATKHLQTPIYIGIMPLTSYKNANFLHHEVPGI
TLTDSILSAMERAADDPLQATTESLAISKSLIDTAMEYFNGIYLITPFIRYDLTIECSNY
IHAKENVVHVTNRI
>A0A1D2UZH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus sp. 2-GBenrich|TrEMBL
MSLKTNVTYYPAMPSAFKEKLLSDEFIVTSEISPPKGVDVSSVFEEAGLVRDYVDAFNVT
DNQRAVMRMSPLAMGHLLKERGLDVIMQFTCRDRNRLALQSDLLGAYAMGMENVCIMSGD
YPTKGDNPGAKPVYDLDSVQLLGAMNQLEGGYDIAGNPLESAPSFTKGAVCNTEPDQPLQ
LMKLEKKAHMGIDFFQTQAVYDIGHFETFMEGISHMEVPVLAGLIPLKSAHMARFMNEKI
PGIRVGDELIARMESSTDPAEEGLLICAEQIRELKKVCRGIHLMPIGHYRHITALFEMAG
LHEKH
>A0A7Y9XUJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium marinum|TrEMBL
MTVILDERQEQRTAHDSPLFASLPGDIDVSFEFFPPKSDRMKEQLWDAIEALAPLGPRFV
SVTYGAGGSTRERTHDTVARIARETNLPAAAHLTCVEATKEDIHEVVDAYWDAGVRHIVA
LRGDPPEKGGTYAAHPGGYANAEELVKGLRERHPFEISVAAYPECHPDSPCAQDDLANLK
RKMDAGATRAITQFFFEPDTFFRFRDDAQKFGIDAEIVPGIMPVMNYASVTRMAKMCGTD
VPGWMEKLFEGLDDRPEARQLVAATLAAELCRRLYAGGVRKFHFYTLNRAELAYAICHML
GVRPKEKAA
>A0A024PAD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacillus karajensis|TrEMBL
MNLRESLQRQTLIGDGAMGTLLYSYGVDRCFEELNLSHSEEVLNVHRAYVNAGADVIQTN
TYGANYIKLARYDLQDQVKEINTAAVRLAKKAADSGQYVVGTIGGVRGAKKQAISLEEIK
RSFREQLYCLLFEEVDGLLLETYYDLEELSTVLKIARKETSLPIITQVSMHEAGVLQDGT
SLPDALKQLEQLGADVVGVNCRLGPYHTIQSLEEVPLPEHAVLSAYPNASLPAYQDGRLV
YPTDPTYFQKSAQSLYEQGARLIGGCCGTTPEHIEAITARVKGKQPIEEKILPFKEKTKV
KESENKDDRPHPHEKARNGRSIIVELDPPKKLKTERFFQGASALQEAGVDSVTLADNSLA
SPRISNTAMASLIKEKYDIDPLVHIACRDRNLLGLQSHLMGLHTLGIRQLLAVTGDPTKI
GDFPGATSVYDLNSFDLIHYIKQMNKGISFSGKSLGESTSFSVAAAFNPNVRNLNRAVGR
LEKKIKYGADYFISQPVFNEEQIIEVYEATKHIDAPIYIGIMPLITARNAEFLHNEVPGI
TLAPDVLEKMELAGTDKAKAQTEGLSIAKSLIDTALDLFNGIYLITPFLRYEMTVELTNY
IQEQTAKQQSLKRLTHSQQAQA
>A0A701H4M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWDNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0H4CFU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PBH53|TrEMBL
MNPALQDDLLDDFSLEMTGKDVPGLEAARDSIPPGTRINITFLAGEDTATRLTAARAVKR
LGFVPVPHISARRLPSRPALEEFLAGLAADGTAENVFVVGGDPARPEGPYEDALAVLRTG
LLRQHGVRHVGITGYPEGHPGIAERTLWSALTEKAAAIGAERFGGDVITQFGFDVDPVLV
WLEALRARGVHLPVRIGVPGPAGVRRLLGYATRFGVGTSASVARKYGFSLTNLMGTTGPD
RFLRTLAERYDPARHGTVKVHFYTFGGLRATAEWITGFRHAATAGTRA
>A0A7G6ZCC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciihabitans sp. INWT7|TrEMBL
MRIPFSFELFPPRNEAAAHTLWDTIQQLAAVGPDFMSVTYGANGSSRESSLGVLRYIREQ
TSVHPLAHLTCVGSSHYEANRLVREFLDAGITSFLALRGDPPRGAVEGDQFLGDLGSASE
LVQLIHRVQTERAQYATLPSRSASGGGVIPSSRQKVRVAVAAFPNGHPRSKRSNQDIDTL
LAKQVSGATVAITQLFFHAEDYLGFVDEARTAGVTIPILPGLMPATAPTRLERILELTGE
RRPEELSRRLHATDSAEEQAEIGIEHAVSLSLEILAGGAPGLHLYTFNQHRAVLSVLDGV
GLIAGLTPPESPKHKESV
>A0A5A7Q0M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Striga asiatica|TrEMBL
MKVIEKIREAAAADNNGRVVFSFEFFPPKTEDGVDNLFDRMERMAAHSPTFCDITWGAGG
STADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALATIKSNGIQNVLALRGDPPHG
QDKFVQVEGGFACALDLVKHIRAQYEDYFGITVAGYPEGHPDVIQNGVAPPEAYQNDLAY
LKRKVDAGADLIVTQLFYDTDIFLKFVNDCRQFGITCPIVPGIMPINNYKGFLRMTGFCK
TKIPPEIMAALEPIKDNEEAVRAYGIHLGTEMCKKIIASGIRTLHLYTLNMEKSALAILM
NLGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTVGWDQYPQGRWGDSR
NASYGALSDYQFMRPRARDKKLREEWAVPLNNVEDIYENFMKFCLGKLKSSPWSDLDGLQ
PETKIINEQLGNINLKGFLTINSQPAVNGAQSDSPSVGWGGPGGYVYQKAYVEFFCSPEK
LNALVEKCKNFSYLTYMAVNKQGSWISNVKKTDVNAVTWGVFPAKEIIQPTVVDPESFLV
ESSYYLVSLVDNDYIHGDLFAVFKDI
>A0A4P6QEV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEDGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A5S5BBS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MSHTRSHSFSFEFFPTKTDAGHEKLLATARCLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVSTAPHLSCVGGSKQELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKMGVETPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMESIQT
FGAQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWDNLKLGR
>A0A0E2HMG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] clostridioforme 90A8|TrEMBL
MDDAEGRERLKMKIREILAEGKPTLSFEVFPPKTEDAYDSVEKAAAKIAKLKPSFMSVTY
GAGGGTSDYTVGIASAIKEEYAVTPLAHLTCVSSTREKVHHVLGELKERGIENVLALRGD
IPQDGSTPKEYHYASELIREIKKAGDFCIGAACYPEGHVESANKSVDMDYLKQKVEAGCD
FVTTQMFFDNSILYSYLYRIREKGIQVPVIAGIMPVTNAKQIRRITQMSGTCLPSRFMSI
VDRFGDNPAAMKQAGIAYATDQIIDLIANGVNGIHVYSMNKPDVAMKIKENLSEIL
>A0A2S8CH55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. J010B-136|TrEMBL
MVPRMSASAPLDYLELDPAGHPRPEKTQQAFSRTALSFEVIPPRHDADQAKIANLLQVLG
SYNPDYIAVTSSKRSGWLEGTAKFIEQISSTTTMRPLAHLACTAGDKRELIHWINVLVDA
GVRGFLALRGDLEPGQTSLPEGYLQHGDELVRLIRQLEGEQAARFAAGRLAVAVACYPNG
HAESANDDEDFDVLLSKQRSGADLAITQLFFDAEDYLKFAQRAQLAGTKMPLIPGIMPIT
SLKRAQRMGELSGLEVPPKLIDKLSRARSPDEEYAIGMAHTVELAQAVIAAGAGCLHIYT
HNNADITQELLTAIGITANSTIKS
>A0A2S4AKF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MTTSRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDTKADLRELLNLYKEAGIQRIVALRGDLPSGMGMASGELRYANE
LVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCYF
YFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIQSIQAF
GEQVISEMCEKLLAGGAPGLHFYTLNQAEPSLAVWNNLKLSR
>A0A3D3SM76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacterium sp|TrEMBL
MVSATGESRLSRQPGEERPDISVSFEFFPPKTDVMEERFWASLDRLAPLGPRFVSVTYGA
GGSTRERTLRMVSRITNETGVPAAAHLTCVGATRDEVDDVVRGYAQAGVRRIVALRGDPP
EGVGHAFTPHPDGYNSAADLVGGIRKLGDFDISVAAYPEKHPQSADWDADIDNLKRKLDA
GADRAITQMFFENGDYWRFVERAHKAGITAPIVPGIQPIHSFRQIAGFAGRCGASIPQWL
ADRFDGLDDDPETHALVAAAVAAEQVTELLDSGITEFHFYTLNRSNLVLALARLLGIRP
>A0A2N2Z3T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-15|TrEMBL
MTIPEHIKKIKGSRLSFELLPPVKGSSIETIFSTLDQLMEFSPPYINITYHREELTYINV
NGRKTPAVVRKRPGTVGIAAAIMGKYKVDVVPHIICGGFSLHETEEALIDLDFLGIRNLL
VLRGDGDKITGKFEPHPEGHRYAYELLEQIMRMNRSDYMEKYVEHPTPTHFSVGVAGYPE
KHQESPNFDADIFHLKQKVDAGAEYIVTQMFYDNTVYFDFVNRCRDKGITVPIIPGLKPV
AIKDHQNILPKMFGVTIPSELSKAMSKCKTNSDVRELGVEWTTAQAKELLANGAPIIHLY
TMGRADNIEEIAKGIC
>A0A3M3NUF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSTEDLRKLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VKFIREETGSHFHIEVAAYPEMHPQARNFEDDLQHFVNKANAGADSAITQYFFNADSYFT
FVERVEKLGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQADPSLAVWNNLQLPR
>A0A369HE92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps camponoti-saundersi|TrEMBL
MPPPDTHEIMSLRQMTLQPAVSMDKITNKIAALPDGAEYISLEFFPPKTAMGFANLRHRM
QRMEQALRPLFVNVTWGAGGATAIKSLELAELCQRELGLTTCLHLTCTNMSRRLIDRTLE
DAKVLGIRNILALRGDPPRKEEYREAIADDDDDNPVDFTWAIDLVRYIRSKHGDYFCIGV
AAYPEGHADGSHPLEQSLEHDLPYLVDKVRAGADFIMTQLFFDIDAYEKFERTLRDHPSG
VFSTMPIIPGLMPVQSYQMIKRTTKLSHAKMPDAILARLDAVKGDDERVKKIGVDIVSEL
IEHIRAVRPGSSSRRGFHFYTLNLEKSVSLIVEQTGLIQEDSSDEAVLDGLLSPPPTMHS
NGNRQTSHSRSSRRQSSVGSDPHNRVIVGDRPVTNPEWEATGQEAGVPASSVNSRANTLA
ICEGEGVLGREATWDDFPNGRFGDARSPAYGEIDGYGVSLHMSVTQAERLWGHPTTPEDI
NRIFVRHVRGELAAIPWSEEGLMAESSTIQDQLVELNNKGWWTVASQPAANGAPSNDATL
GWGPANGFVFQKAFVEMFVPADDWRRLSEKLRSDNICFYAANAAGDFVSSDESGGVNDVR
VPPSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWGEWARVYGRGSASEKLLRGI
REDYWLVNIIHHEFLEPHALWDLLR
>A0A1G7LV73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia oroxyli|TrEMBL
MSRTFSVVCEIEPPTRPDLTRARHQIGMLAPVVDDFLIPDNHIGRATVSSIAVANEVHAM
GRRSIACLNSRDRNLLGLQRDLLTAAAYGVDRFLFVAGDKPTAGDRAGGLTVRTMIEEAR
AITGRREFAGVEPFGIGVTSGSRRRLAPWKRAADFVFLQVGFSVEEVVRWREENPTDQPV
YAGVMVLASAGMADRLRASVPDIEIPAALVERVRADPDAGVAAACEQVVALRESGACDGV
HFVPVSRYRQVAIELERLRPRPR
>A0A356B871|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rheinheimera sp|TrEMBL
MAFANAQYLEAINRNLQDIDGKVNVSFEFFPPKTAQMEQTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDATKQTLVDIAKDYWQNGIRHIVALRGD
LPPGSTEKPALYAADLVEILRSVADFDISVAAYPEIHPEAPNAQFDLLNLKRKVDAGASR
AITQFFFDTEKFLRYRDRCAAIGIDVDIIPGILPVTNFQQLQKFAALTNVAVPQWMHKAY
EGLENDAATRNLVGANIAMEMVKVLSREGISHFHFYTLNRSELSYAICHLLGVRPQIAV
>A0A2S8PHL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. AR247|TrEMBL
LMGFDALGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQK
ANFVVGAAFNPHGKHLDKAVLRLERKIAAGADYIMTQPVYDPELIRALKEATSHLDIPIF
LGIMPLASGRNAEYLHNEVPGIQLSDDVRRRMSGLEGEEGRAMGVAIAKELLDVAMEHFN
GIYLMTPFMLYDMSAQLISHVWEKSGRRQSPLFHR
>A0A1M5GCT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salegentibacter echinorum|TrEMBL
MKVTEHIEKANGKTLFSFEIIPPKKGKNIQELYDNIDPLMEFKPPFIDVTTSREEYVYLE
KDGLLDRHITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFSKEETEYLLVDCHYLGIENV
MALRGDAMSHQKYFEPSKGGHNYACELVRQIRGINNGKYLHDVVEVDHKSDFCVGVAGYP
EKHLEAPSLKTDMKRLKEKVEEGADYIVTQMFFDNSKFFKFVEDAREAGISVPIIPGIKP
IAVKRHLQILPQVFKIDLPEELIFEVEKCKSNAEVRQVGVEWCIQQSKELMEFGAPVLHY
YSMGKSSNIQKIAKEVF
>A0A6P0WTD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldora sp. SIO3E6|TrEMBL
MTKLTHNSFRAAAQSGEFLITAEIAPPKGGNPDHMLKMAQALKGRVHAVNITDGSRAVMR
MSPLAASVILLQYGIEPICQVACRDRNRIGLQADLLGAQALGIHNILALTGDPVKAGDHP
DAKSVFDLESVRLLKIITRLNQGFAANDKPLTDGATDLFAGAAVDPQLKSWSGLQSRFER
KIEAGAQFFQSQLITDFERLEKFMDKIAAGADKPILAGIFLLKSAKNAQFINKYVPGVNI
PQTIIEQLANAANPLQEGIKIAAEQVKMAGQICHGVHLMAVKREDLIPQILDLAGIVPLN
KAK
>A0A838YTX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilus sp|TrEMBL
MTIRYEANPPKVLPDVDTNESIAKFIKRIKIISKKCDAIHLTENVLGYQRVSPIEVGKII
RKEIPDMPITVSLRVRDKSEKEISEVVENCISIGFSGILVLMGDPSQTGKPDSNQIPSAT
VKRLREQGVDSKIDLYLSMSNKPNFSKITKKLEAKPKGFMTQVVQNIEQAQNLFDNLKEF
LVIPIILFPSAKNEKSAKFLNLDLASYSKDFDEFVKKVHTITDDVLITSPNDFNGLNEFL
EKSFS
>A0A7X1L6R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MPEKDFFISVEVVPPAGPDADPLLDALAALDNLPVDAFSVATNPVAKPRMSAMALCTLIQ
QRTGRAAILHCTTRDHNRLSLQGLLWGARALGLETVLITTGDFVALGDRTTTSDVRDLDL
FDLLGMATAAGLRAGVVLDPHPETNGLQHAAERLARKVDAGAQFVVTQPVYDAAAADALA
EATRSIGIPLIMGILPLRTPRHADFLHTKVSGIAVPEPLRQRMHQAADPIAEGILNARET
LTLARERFAGACIMPPFDHYEILPAIL
>B2UQZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc)|TrEMBL
MHLRERLQSGAGPSLSFEFFPPKNEQAASALYQTIRELEPYRPSFVSVTYGAGGSTRELT
REVVLRIQHESRIPTVPHLTCVGHSREEVWNILDQYARAGVRAVLALRGDPPRGAKDYNR
DADVFRHAADLVTFIREYNESGRHPDPDGFAIGVAGFPEGHPATPNRLREMDFLKAKVDA
GADYICTQLFFDNHSFLDYRERCLLAGIKVPILAGIMPVTSLSGMNRMAELSGGTCFPAR
LLKALKRAGSNPDAIQEVGIQYASSQCAELLDSDVDGIHFYTLNQSRATREIYRNLGLKD
SLQLLEHGEDK
>A0A6L6GGK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. YIM 103518|TrEMBL
MSQLSSYFQQNQFCVLVEYLTSLTEVFPTKTVFAGYPAVMTLADRVHSDHDILPLEASEN
YSNSVEKVIHFSGKGRDIKDFELFLKQAKTAHIKNLLLLTGDKLKEHEDGKNGALRSRYL
ESVNAVMAAKKQGDFNIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIITQLGYDIAAL
KQAQLFLKKYDYSQKILACVMPLNLARAKFMVKHKVAGIVISPHMLKVLEHEKQQGLSNN
AHMRCALQILICKKIGFAGVHLSACHKPEEQILLEQYIDEYRDLELSELELLWNELWQIK
TGDEFKPELAYFSRAVTSSERIKYQQLHLMHAALFESKVAKGFGRFVFDAPLWKSRTATK
ALMKTEFLTKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAQAVGQTNILKEKLIPTVAIEVRGTSSWKNWYVNGS
>A0A7C0WVA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MTTQNKFSRSLLDPEQFTITYELVPGQGSGGRRHERLLEFARQTYEDGRIKALSITDNAG
GHPALAPIAIGSEVQAIGLEPLLHFSLKDKNRSQVESHLFLYHRQRFHNLLILGGDFPRP
NYYGQAKPVFDLDSVQTLHLLREMEDGSYQRGSATGRGTTFAPLSFLRGCVVSPFKTTEA
EQVWQYAKLLKKIAAGTNFIITQLGYDVCKLEELIRFLRETGNTLPVLGNVFIPSLGVAE
YMGRGGVPGIVFPQQLIRRMQEEAVRQDTESRLLRAAKMICVLRGLGYSGVHLGGNGLNF
AKVRFVLDTAEAMQDQWPSLREDVHFPADNSWYLYPPSANGVCGKKRGALAPGRRQKAQR
LHQLTHRLLFAPDQSLTSRLFGRFCRYCAKSKGRTALLGKLEKAIKALLFSCRMCGDCTL
AESTYLCPQAGCPK
>A0A7C0WTS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
RQAFNEQIAALVEGGVDLIMLETFPCLDEILPAIAAARAVAPHLPLVAQMVFPARGMTVR
GEDALTCGRAMAAAGADVVGTNCGRGIDAMATAVRRLAPLAKEGVILSAFPNAGMPEMVG
HRMIYPAQPAYMAMRSGEMIRYGVHLLGGCCGTGPEHIHEFRSTLKIRPVRIPGGRLVVA
PDKTPETAVAVRTGGFLAGLQTNRLPIIVELDPPTHLDVAPVLAGARALTEAGVDAISLG
DNPLATLRVGNLGVASLMRKETGIQTIIHQSGRDLNALALQARMMEAHLLGIEAVLAVSG
DSASATDQPEVSGVFDLRSYGLLRMLRQLNGGLNMAGRSIKHKTNFSVGAAFSFRPDNPQ
LQISRLEKKFELGARFAMTQPLFSREAVERMMDKTSHLDMLIFPGIFPIISARNAEFLHN
EVPGMSVPAEFRRQLASYPGVPDQRKAALDYTRQLVEDIAPIVDGFYFVSPLNKWDIALE
FVRQVRQAGWQGSGRATP
>A0A2A3ZT12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MKGTSMIQMAPTGLLTDFSLEMTGKDVPKLEEAAHAIPQGARVNVTFLGNEDLTMRVDAA
RVVKRLGFVPVPHISARRLKSQAELEEFLEALQQVDASEHVFVVGGDPATPEGPYTDSLA
VIRTGILKDFGVHEVGIAGYPEGHPDIRTETLWEHLTAKSTLLAEQGLEQVVLSQFAFDA
DKVSSWIRAVRDRGIDSTIRIGTPGPAGIKRLLGYAKRFGVGTSAGIVKKYGFSLTNLIG
TAGPDRFVTDLEQKVSAADEAAAKIHFYTFGGLLATAEWVQQYSAGK
>A0A525D1H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSFVANSKLEKVLKAGHLGVTSECGPPRGTNPEEIKEKGALIKDYVDAVNVTDNQTAMTR
MSSLAACIHLKLMGVEPVLQMVTRDRNRVALQSDILGAASFEIPNMLCLSGDHQSFGDNP
QGQNVHDLDSMQLIQTVRHMRDDGKFLGGDDIKQPPKIFVGAAANPFADPFEIRVPRLAK
KIACGAEFIQTQCIYNIDKFKEWMRRVVDRGLHEKCFIMAGMTPMKSVGMAKYMKNRVPG
MDVPDEIIDRLASVDKKDAAQEGINICIEHIQQLKEVEGVAGFHVMAIEWEEKVPEIVEK
SGLYPRPDVE
>A0A3N5IJA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSIQKRLQSGEFVVLAEMNTPKGVDISRFMTDARRLKGRVDGIVVPDMDNGVMRMSALAG
AALVQQQGIDSLITVYGRDRNRMALQGDLLAAQVLGIQTLIVVQGEAMANSDHRNALPVD
DLDELGLLAAIQTLQGGKDLAGFDLEGRPEFQVGCRLAPYADDAGLNRELDRTREKIAAG
AGFVITPPVYDLNRFEDFMGKAAALQAPIIPSVFLIKSVAVARYIIANEPGAAISEDLIR
RIRKSSDRELEGVKIAGETIARLRKMARGVLIQTLGWEHRLPAILDVAGI
>A0A4R7Z4K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium saccharolyticum|TrEMBL
MKIKNIFEEKEVVFSLEVFPPRPDVPIDNIYQTLEELKDIDPDYISVTYGAGGGVRKNRT
CELSSIIKEKYDVEALAHLTCINSDQETLNKILARLESKSIENILALRGDKQVDGEAIGD
YNYAYQLIEHINKNNDFGVAAACYPEGHLETDSLEQDLEYLKQKVDFGVDYLISQMFFDN
SLFYKFRNKAEKKGINVPIEAGIMPVINKKQVGRIIELSDAYFPEKFQKILDKYEDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKAD
>A0A194UTY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Valsa mali var. pyri|TrEMBL
MHIKEMIAEAEKTGAPSFSFEYFPPKTLTGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVSQAQAYLGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPRDKEK
WEAADDGFNYAKDLVAHIRATYHDHFDIGVAGYPEGCDDNKDEELLLDHLKEKVDAGATF
IVTQMFYDVDNFLRWVGKVRARGIDIPILPGIMPIATYASFLRRANHMNCRVPQEWMDAL
EPVKNNDVAVREVGKTLVANMCRKIVAAGIPHLHFYTMNLAQATRMVLEELDWMPSDRSP
LKQALPWKQSLALGRRYEDVRPIFWRNRNKSYISRTMDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSVKDVATMFVKYLNKELDQLPWSEAPLTSEADSIREDLID
MNTRGLVTINSQPAVNGVKSSHPIHGWGPANGYVYQKAYLELLVSPDVFPELISRIDKHP
DLTYYAVTRAGNFRTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGMDW
ARCFDAGTPSRILLERMMGEWYLVNIVNNDFHQPRTIFEVMNGLQVKDLDVEVQPDGPAA
N
>A0A2K0XXP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moraxella sp. RCAD0137|TrEMBL
MATHSVSERTTKAKTPFSFEFFPTKTDEGQDKLLGVFDELNALNPKYFSVTYGAGGSTRE
RTLGIVKALIEKGSTPIAPHMSCIGDTKSQIGELLDYYKALGVDRVVALRGDLPSGQVGY
GELPYALDLVKYIREHSADHFSIKVAAYPEMHPQARNFEADIDNLVAKYHAGANEAITQF
FYNPDSYLFLRDRLAKKGVHQDDFPIIAGIMPITNASNLIRFADGCGADVPRYIRKQLAD
YGDDRKAIRQFGFDIVHQLCERLISEGVPSLHFYSMNHTEPNKALVESLGLI
>A0A5C6YUY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aequorivita lipolytica|TrEMBL
MKVTEHIKNGNGKTQFSFEILPPLKGENIHSIFENIDPLLEFKPPYINVTYHREEYVFKE
LKDGLIEKKVVRKRPGTVGICAAIQNRYQVDAVPHILCGGFTKEETENFLIDLQFLGIDN
VMALRGDAVKSETYFTSEKNGHKYACDLVSQINALNKGKYLDDALQHTFPTDFCVGVAGY
PEKHMEAPSSESDIHFLKKKIKNGAEYIVTQMFFDNEKYFKFVEKCRAGGITVPIVPGLK
PIAVKSHLNLIPHRFKVDLPDSLVMEVVKAKDNKAVREIGIDWCVQQSQELVKAGVPFLH
YYSMGKSSNIKEIASRVF
>A0A1T5C1P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetoanaerobium noterae|TrEMBL
MGLLKQAFENGEFAVTSEMAPPKGIDFAHLRHCAQLIKGRVHAANVTDFQSAVMRATSLA
TCKVLQEEGIEPVIQITGRDRNRIAIQGEMLSAGLFGIPNMLALTGDHTVVGDHPNAKAV
YDLDVIGILQAAEILKSGKDMAGNELQGTPDFFLGASVTPRFDPVDAQIFKMEKKIAAGA
KFFQTQAVFDIETMRDFREKTKHMDCKIMAGIIPLKSPGMAKFMNSNVPGIFVPDELIDR
LKASAEGIEDKKEKNKAMVMEGIKISGEFIKQLREEGLCDGVHIMAIGAEENVPLILDAA
GL
>A5DXM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)|TrEMBL
MKISEKLHQAHSGSTRPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAG
GRSSSLTNEMVYTAQSTLGLETCMHLTCTNMKIELIDEALSKAYKSGCQNILALRGDPPL
DGSESTGDFKYAKDLILYIRKKYGNHFNIGVAAYPEGHPEEEDESKTLHYLKEKCDAGAN
FIITQMFYDVDNFISWCAKLRKIGVEIPIIPGIMPISTYAAFIRRAKWSEIKIPPHFLEA
LEPIKDDDFLVREKGTELVSEMCQQLIESGYVNHLHFYTMNLEKATVMILEKLNLVEAIK
SHDLVGGTELPWRKSLHPERSKESIRPIFWQNRKYSYVSRTATWDEFPNGRWGDSRSPAF
GDIDLCASELLRQSPKRAYELWGTPGSLKELSDIVISYLKGDLKSLPWSDGSVGDDTKVI
VDDLVELNKRGLLTMNSQPALNSIKSSEKIFGWGPKNGYVYQKQYLEFFCHKDIIVKLLQ
TIDDYNNNQGDASSAIISYYAVDLKGNLTTNCNDDDINAVTWGVFPGEEILQPTIVEKTS
FLAWKDEVYRLFSEWRKVLTSNLADVKDEDKKNLHKFEKLMTEFSEDYVLCNLVNNDFID
SNSTLFNLIYGLDLQVLE
>A0A8C3E8M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corvus moneduloides|TrEMBL
KAVSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLRDKMRRRQDAGDKWFSLEFFPP
RTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILH
MTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVKHIRNEFD
DYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFVITQLFFRPETFLKFMKDCQAIG
ITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCR
ELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRVEDVRPIFW
ASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTC
EESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGILTINSQPN
INGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQN
ITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRM
IIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLNSPTQQ
>A0A7X3IF66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. 2A|TrEMBL
MRRSTHRASRDGYHPIRVSIEFFPPKTEEMEKILWASIERLAPLQPSFVSVTYGAGGSTR
ERTHNTVARMVRETSLKPAAHLTCVDASREEIDAVVQSYWDAGVRHIVALRGDPAEGVGH
AYRPHPEGYASTAELVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQA
ITQFFFENEIYLRYLDKVRAAGITIPIIPGILPVQNFKQAANFARRTGASVPYWLAARFE
GLENDVETRRLVAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKLA
AAKAAA
>A0A7C5GCK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia sp|TrEMBL
MINLQVPEPFDPLAHEPLVPPSGHYSAGKLERVLRKGHFAVTAELNPPDSADPRDVLKAA
EPLVGVADAINATDASGANCHMSSMGICSLLSRAGQGTVFQISCRDRNRIAIQGDVLGVA
AMGVGSILCLSGDGVGVGDQPGAKAVFDFDAISLLRTLKTMRDEGVFLSGRKLTTPPNIF
LGAASNPCIQPLEWRAERL
>A0A090NKU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella dysenteriae WRSd3|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVPAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A434AUZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylomarina longa|TrEMBL
MKVIELLNQAIENKTTHFSFELLPPLRGNSIYKVFNTIEKLKEFDPKYINITAHRDELVF
TESENGVFEKKITRKRPGTVAVAAAIKNKYKLTVVPHVICSGFTPEETENALLDLNFLGI
YDLLLLRGDSSSRHEFISSEGEHKYAIDLIHQVNKINKGEFLDGTHVEPFETPFSYGTAG
YPEKHEEAPNMDSDIYWLKQKVDAGADYIVTQMFFDNQKYFDFVQKVRAAGITVPVVPGI
KPLSALSQLTALPQIFKTDIPEALAAEVRKCKNNEAVKQVGVEWGIQQGKELIQQGVPSL
HFYTLMASDCVRKIAKAIY
>A0A424NMY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium TMED96|TrEMBL
MKIIDHLKNKNDSSQFTFEILPPLKGQNLESIFXAIDPLMEFKPPFIDVTYHRXEXVYXE
XDNGLLQKHVIRKRPGTVGICAALQXKYNIDAVPHVLCGGFSKEETEXLLIDLDFLGIEN
VVALRGDSLKSEVYFKPSVDGNSFASDLVKQIVDLNKGKYLDEEIQNKAKTNFCIGVSGY
PEKHIEAPSFDSDINFLKKKIDAGAHYIVTQMFFDNQKFFDFQKKCLENKINVPIIPGLK
PISTKKQLNVLPQRFYVDLPDDLIKSVIKCKXXDQXRQVGIEWCIEQSKELKKAGVPFLH
YYTMGRSDNIKSIAESVF
>A0A4R6XJ71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinicella litoralis|TrEMBL
MNKQKQFGLSFEFFPPKTPEQKVILLDTQEKLRKLNPDFFSVTFGAGGSTITATAETVLE
LKTHETPKVIPHLSCMGGTPQEIEDLLNQYIQHGITDILALRGDVPSGMGSVGYFRYANE
LIEFIHEKYPNTFNITVGCYPEIHPETESFESEIKYFKQKVDAGVNRAITQFFFNPDAYF
NYVDHCEKAGIDTPITPGIMPITNFSNIKRFCGFCGTDMPRWLQYKLQSYGDDRKSIQQF
GTEFTIKLCQQLLDQGVPGIHFYTLNRAKATLDVVEALQ
>A0A0Q9CYI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. Root275|TrEMBL
MIAANAQGTGFPVSFEFFPPKTPEGADKLRAARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVGAASHFSCIGATRQSVREQLAMLKDMGVKRLVALRGDLPSGYGAGGEFHY
ASDLVAFIRSETGRDFHIEVAAYPEVHPQAKSPEADLKAYIAKVQAGADSAITQYFYNSD
AYFRFVEDAQRLGANVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A2G6ECW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB3 bacterium|TrEMBL
GGVDQPLGEYDCSAQILETGLLDKYHVKSIGLAGHPEGNPDISDEGIKAALAFKNAFAER
TDAKCYLVTQFCFESEPIIAWDKALQAEGNKLPIHIGIPGLASLKSLIAHSRACGVGASM
RFLTRQAKSFSKLLRVNTPDKLCIDLATYKFTDANCGIMGMHMYPLGGLKKTAHWSYAVR
DGNFTMSANNDSFKVHDYSKS
>A0A0G3UZ50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium IMCC26256|TrEMBL
MKIADALKAGPCYSFEFFPPRSEEAERNLATAIRELAPLAPAYVSVTYGAGGSTRDRTHD
LVVEILRDTGITPMAHLTCACHSRQELVDVVTRYRDAGIENILALGGDPPADSDQPPGEL
KYASELVDLIRGVGDFSIGVAAHPEPHPHSPSIEEDRRRTAEKLSKADFAVTQFFFDARH
YFDLVESMHALGVDKPVIAGIMPATSMRSITRMSELQGSEFPRELAAKLEAAEPDGPEAV
HRVGVEEATRLCRELLDRGAPGLHFFTLNRSMATREIYEALGL
>A0A1Z4Q2Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scytonema sp. NIES-4073|TrEMBL
MLDTINPTALTSFRTAAKTGQFLITAEVTPPKGGNPEHMVRMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQNGIEPICQLACRDRNRIGLQADLMGAHALGIYNILALTGDPVKA
GDHPDAKGVFDLEAVRLLQLIQKLNHGVDCNQKPLTDGALDLFPGAAVDPQCASWSGLQS
RFERKLAAGAQFFQSQLITDFERLEKFMDTIAAGCNKPILAGIFLLKSAKNAQFINRCVP
GVNIPDHIIDRLAQAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIVPILDMAGV
GVVS
>A0A2D6CSN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MRQQGASTGRQRSIVNTSPFRREIAESEDFLVTVELLTTPADGVDSYVEFFQAFADRYEH
RAGSPKIVAVTSPHSPGGMATLDPFNVWAESAGALPEGLDAIAHVACKDMNRNGLETHLR
NLRSVGVGNILALTGDHPINSAPVFDLDSLGLLQLAMEVNGRFIKFEEPEGLDGVFQFSA
GAGMSPYKYTLASAWQQYAKMLKKVTAGASFLITQVGYDIVMSADLIRYARAHDMQAATF
GNVYLLTKGAATKMHAGDLPGCYASDELMTAVEREWRTSARGREAALTRMAHQTALFEAQ
GYRGAHLGGWGLTYDDVIEVLDRAREISDAGVDPEAMREWCHFAPPGAEYFIGEDGEFIL
PSETPKRTPLQKRLEFFHDHVVDVDSRLGAAIAKAAAKDPDREGIRARALYGAERAAKAL
LVECKDCGDCRLPDNYYALCNEAACAKGLPNLPCGDSDSVTGMCGNADVTCAGELVFYAA
FARGKLGELAEQVQSSKVPSLRGSSAVINYLSGHDHNARIAGEVRREKTLPITVVGESVH
AQIPRVNWSMASLGTDPGAQMNGPLAYVHDVIVTQINAGADYLAINVDDFGPESRADMMR
FYVDMVNTIGRGVPVCIDSSDPDTKAAGIDQYFRTARDPQTLPMLNSINMVHPKAVLELR
ERYPFKVVAMLHETVDKDGVPVAIESPDQAHGLAVDMFEMLGSAGFEADDIFFDTAVTPI
AADLEAKRAHQTMHGIRAIANDPGLEGARTLIGLSNCSHMMPNRRAVNRAYLHVALEHGV
TAAVLDPTVNYGEREPGKQILSIMRSLADNDGSDMTAGFEIFTKIADYSRRYGRK
>A0A1H1BVZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronobacterium texcoconense|TrEMBL
MASEIQTAEMAEGIVELLEQPRFELMPFESMDEQLEHLPDGSEVAITTSPTLGLEATIDW
SERATDRGFEVVPHIAARYVRDEDHLEEIAGRLTDAGVTDIFVPGGDREEPVGEFTSAYE
LLSALEDLEYEFEEVGITGYPEGHEFLDEEVLAESMAKKEPYATYIVTQLCYDAETILEW
IGEIRDRGVELPVEVGIPGVMKYQRLLNISKKVGVGDSIRFLQKTSGVIGFIRELVGSRG
TYVPDELVQGLAPYATDPYYDIRGVHVYAFNQVPDLESWRSETLTQYG
>A0A3D2RWW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MKNRLCKELGSRILVCDGAFGTQLRKKIPSYVTCLDACNIDSDYLYIVQDIHREYKVVGV
DIIQTNTFGANAKKLEFHGLDEQVREINAAGVRLAREVAGEDVFVAGSVGPIETSPFSNE
FSAKEVGSAFKEQMEVLVEGGIDLIMLETFSDSREVEIATQLALTYDLPVVVQIRGMPRG
KLSDGTDICVFARQMENLGVAAVGINDRPPHEVAEILKRLAKIVNLPIIVQPDAGAPRMS
QGKLLSEEYTVAPRLYGEYVNDFVKLGANIIGGCCGTTPEHIQQIKMVTEGIPPTEREKQ
VFVFKDVPKSFKLEFDSNPIQQIFDEKDAIISVEMRAKTFTQFSAMIRESKNLAKAKIDL
FDVPDNAGATVNIGAIGTAFRLQQETSVPTIIHWTTRQRNLISTQSHLLEAWALGVEGIL
ALSGDHPKVGRFETARIVADLKGSVQLIELITRLNANQLINGTSIDGPCNFYIGAGFNIA
EKLENQVKHLTQKVKNGAQFVYTQPVYTLDDIERTYEATKHLGVKVLYGIMPITTPRSIP
FLRDNLGIYIPRSIVEQFSEMGDAMSTCFGLEMINNFVYNLGQQNRVPIDGIYVIPPSNV
NWKNKRKAVIDIIEAYRGQIVAE
>A0A1E9K7G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria sp. HMSC074B07|TrEMBL
MSYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHSIVKRIQQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A7G9YYP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon ANME-1 ERB6|TrEMBL
MTDEVYSDLMREFKEGKYVFTGELEPEKAGNVNEPIEMAKELKGLVVACNVTDNPQSFAY
VNSMAASYLIQKEAGMECVYQLRCSDRNRMALLSDVLGAGALGLKNILALAGDHVSLGDT
PDAKPVFDLDSTTLIAMIRKMVDEGKDLGGNEIADPPKLHVGGAAAPGAAHLKAEVGKVK
RKINAGVEYLQTQVVYYTDVLDKFFNELGETDVPILVGIFPARTFGQADFFDKYVAGVDV
PPDYLEAMRATKQIKDKEKKKEEVDRVNIEFFTGFLEHLKGTPAAGCHMMAVGYPRIIAP
LKKVME
>B8J2Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949 / MB)|TrEMBL
MHIGDSIRAAQKPFFSLEFFPPADEANLPAFFETVEQLRPLAPLFASVTYGAGGGKQRNT
LAVTAELARRGLNTMAHLTCVGADPESISTYLSELRAAGVDNVLALRGDPPAGEEWDWNS
GRFRHASDLVTFARRQQPYMGIGVAAYPAPHPESTSISQDRRHTADKMRSGADFAVTQLF
FDAREYADLLEHLRGQGIHTPVIPGILPIQSFASLRRVLALCGANIPGKLYLDLEKADEK
GGVEAVREVGLEFAVRQIRFLLDNGAPGVHLYTLNKADMCLRLAQESGLLGPDVNLPAA
>A0A7C3UE95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MKIDDILKDKKRSISFEFFPPKTEQAEQVLFETIEKLSSFNPSYVSVTYGAGGSTRDKTM
STVQKIKQKTSLTVMPHLTCIGSEKKEIAEILDFYKSIGIENILALRGDPPMGVTELPDI
KDGFDYAKDLIEFIEIYGVFSIGAAAYPEKHKESPNMEFDMIYTKDKVEAGAKFLITQMF
FDNRFFYGFLDRAEMIGIDVPIIPGIMPITDLKKIKQLSLMCGASIPYPLNSLINKYGDN
PEDSRKAGMEFTIEQCRNLMENNVRYFHFYTLNRWEAVSEIINILKLFPI
>A0A800AJF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MKAGSNLEKVLSSGEFAVTAELGPPKSADPQVIIEKGNILKGYVDAVNITDNQTAIVRMA
SIAAGAIVVKEGIVEPVMQMVTRDRNRIAIQSDILGAAALGIKNCLCLAGDHHSSGNHPS
AKNVYDLDSIQLVAMLKAMRDDKVFQCGEEIEEVQPQLFIGAAWTPLADPKEIRVIRLAK
KVAAGADFIQTQGVYDVKSFAESMKKACDMGLCEDTYILAGIIPLKSAGMATYMQKSVPG
VNVPDEMIKRLKDAGRKRAGAEGRKIAVELIQQLREVEGVRGVHIMAIEWEERVPGIVEK
AGLLPRPSL
>A0A496B940|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
METTHSRKNNFIDTLTRQILVCDGAIGTELRRQVPAHLQCVDACNISTEHAEKVAMVHRA
YADAGADVIQTNTYQANREALAVHGLAEQAEEINRSGVRLARAAVPETCYIAGSVGQIPF
QTLDTALPSTKAIRRIFKAQMDALVDEGVDLLVLETFVSPKQAEVATKQALTYDVPVVVE
ISGVSGGTVGAGVDVRVFAQELEQLGAHAVGINCRGPHDLVEAMELLAPVIKVPIAVQPN
AGNPRVEQGEVALSYTVEAEVFSDYVGKLIELGANMIGGCCGTTPAYVAKIRQAVREREP
VERQQRIFVLPKIRATSKVRTDNPVQQVFETREQIISVEMRANTFPQLRAMLREAKNLAA
IGVDLFDVTDNSGAAVNIGAVGTAYRLQQTTQIPTLIHWTTRSRNLISMQSHLLEAEALG
IRGIVALSGDHPKVGPYEAASLVPDVRGAVQLMKLIARLNQGELADGSSIGDPCGFYYGG
GFTVAENLQPHVKHLTNKVKQGAKFAYTQPVWTYEDIVRTQQATEHLGIKLLYGILPLTS
FRSASYLRDNLGLYIPQFIVDTFRDLEDTAAHELGIRLCLELIRDIRNQNECKIDGIYLI
PPALMNWKNRVRIISEIVKTYRFF
>A0A2E8DU33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MSDFLHQIEHRILVGDGGLGTQLRLRLPSNIPCLDACNIDPIFRNFVYEIHADYGRAGAD
IIQTNTYGANQLKLDLQGYGNQLESINLAGVQLASQAATEISSSQNRQVFVAGSVGPLET
NPLEDELSITEVRQAFTAQMEVLVSAGVDLLILETFTDLRQTKIATKLAVKFGLPVMVQI
SGISKGVVSDGTDVRVFAQTLSQLGASVIGLNCRGPHDLLLAAEKIARVTDIPLSVQPNA
GTPRIDQGKISTTYSVSPDHFSRFIKRFLSLGINVIGGCCGTTSEYISVIRENADGYVPA
RRQTQIFVFPDNQKSSKSKNSPNPIEQIFETNDRIVSVEMRANTFPQLRAMIKVSKNLAD
LEVDLFDVPDNAGATVNIGAIGTAFKLQQVSNIPTLIHWTTRQRNLISIQSHLLEAWALG
IKGVIALSGDHPKVGRFETAKIVTDVRGSVQLMELLKRFNQGTLIDGTSLGEPCDFYVGC
GFTITKNLKPQLRHLRRKVERGAKFIYTQPVYDLSTAEDVYQSIKNEGFDTKILLGILPI
TSLRSISFLQDNLGMYIPSTVVKQFQDIDNPKDQLLYGLSIARDLVSRLSEQNRFSVDGI
YIIPPSRMNWANKQVAITQLVQSFRKRKTEKR
>A0A2E4J119|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutaceae bacterium|TrEMBL
MTTLADKLERSQDFLIGAELVSTRGTVEEPRAAKTVAFAHELAASSQVDWVSITDNAGGN
PMLAAAALAAPFRDTDRSVIIHLSCKDFNRNGLESQAWHLASEGLNNILVLTGDYSGTGV
SGGSKPVFDIDSIGLLGLLGKMNGGLDVAQPNAKKPTHLAPTQFYSGAVVTNFKLHENEV
MPQLLKMEKKLEAGAKFLINQIGYDSRKIHELHAWMQQRGHGDVPLIGNVYVLSPGVAKV
FNAQKIPGVVVSEELAAICEEQRASADKGKQFFLELAAKQVAIYRGLGYRGAYLGGVHTV
AEIERVLEIEKSYGPDDWKQFAREIRYSRSGEFFIFDEDPETGLANPDKLHPDYEGSLQK
RTKTPNVNLTYRFSKFTHDLMFAPGKGLWNIGAKLCGNAKDTMQGPPGMHAVEHLGKSVM
FGCKDCGDCSLPDIAFLCPESACAKNQRNGPCGGTRDGKCEVDDFECIWARAYDRLKYEG
REQDLLAHAPVVQDQNLRGTSSWANTWLGRDHLTKKQPEESSK
>A0A1B4EZ54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. LA-2-3-30-S1-D2|TrEMBL
MKSIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAATATRTICERLAM
>A0A1C3NRM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas bromi|TrEMBL
MIANDTPSLASSITDAYSLEVSVKDSGALTKAAPRIMPGSAMFIPYLPGQDDAARLAAAQ
RARRLGFDPIPHLSARRIGSLKELQAFVERAVDDAGVTRCLVIAGDPSTPMGPFPDSVSL
IDTGVFERSGIRTIGVAGHPEGHPIMRTAEQWDVLERKCRRIEERGMAPLIVTQFGFDAD
KVVTWVEALRAHGIAHPVRVGVPGPASVAVLARYAASCGVGACASVLSTYGISIGTLFGN
AGPDRFVDRLASQLTEAHGDIRLHVFPFGGIAQSVEWVVQYRSRTASQDRSSSVRADRA
>A0A3N0DT35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmoricola solisilvae|TrEMBL
MDITTSIRSGQGDFVLFAITPPRQSTPPERLPEIARATIERLEHLDLDGLVLYDIDDESS
RNPAERPFPFSPTVDPAEYLSAHLAAWPTPVVVYRAVSKYPHDGLDAWLREQDPSRTLTV
MVGAASSGTSAPVTLSEAQAMRAEANPDLLLGGVAIPERHSRRENEHLRLIAKQEAGCRF
FVTQVVYDLNAAKNLVSDYRYECEARGLTPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLRHAKNPLAASLDQALATAVELVDYCRRLGVPFGLNVESVSIRREEIEASVDLAEQL
IAHLR
>A0A1F8MRK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_52_12|TrEMBL
MSLQSKLESGKFAISCEFGPLKGTDTHEIKENIEILKGKVDAANVTDQQSSVMRMSGLIT
SALCVQGGLEPIFQMTCRDRNRIALQSDLLGAWVMGIKNVLSLTGDLPSLGDHPQAKGVF
DLDSVTLLQAITRLNEGFDMSDTELKGKPSFFAGAVVKVDSNTEASEELQIAKMQKKISA
GAKFFQTQAVYDPASFGKFMKRVEKYKVPVMAGIIPLKNVGMAKYMNANVAGVHVPDNLI
EKMSAAAKEDREKVGIQIAADCIKQMKPMCQGVHIMAIGWEKKVPEIMAAAGL
>A0A1Y1IZB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas testosteroni|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAELESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A4P8TH96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium sp. SGAir0954|TrEMBL
MSATSTLPDRAPAAPARRRPALSYELFPARSDVSFERLRTTIAALEQTAPDYVSVTSKTG
QGNLDRVLEVTEHLLDATTLRPLVHLTSIGSTRAELAAIVGALLDRGVRGVLALRGDQPE
GHRLDDDEVPFARPLVELIRAVERERTAALAGGRLSVGVAAYPHRHPESPTAQHDLEVLM
AKERAGADFAITQVFFDPSAYETFVERARTAGIGLPIVPGFVPATNPRRLARLAELSGVQ
APRELLHSLENARDDAERHRIGVAHTAGLAARVLDAGAPGLHLFTFNRHVEALDVLDALD
LDRWSAPTAGDLR
>A0A2G4I8N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedosphaera sp|TrEMBL
MRFIRDIHAAKKALGQPVISFEFFPPKTNEGEKNLFEKHIPELMKLRPDFCSVTYGAGGS
TREKTIGIVDRIQREHGLTAMMHLTCVNATKDELTAVIAEARQRGIKNILALRGDPPAGG
EFKVTPGGFEYSHQLVSYLDELGGFGIGTAGFPEGHIACKNGKLVDWDRLKAKIDCGADF
VVTQLFFDNADFYAFRDYLAKKGVTVPIVPGILPAHSGSQIKRFTALCGAQLPAPFLAGL
DKCGADDAAATEFGIEYATAQCADLLKNGAEGIHFYTLNKALASTRILQNLKLA
>A0A2E5K510|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutaceae bacterium|TrEMBL
MKNRSIATLFEAGKSIKSLEFFPPKTEKDTQRLFLAASRLKAFEPDFVSVTYGAGGTTRQ
YTQEITARLQNELGWLMMPHLTCVGSSQNDLLETLRSFHAEGFRNIMTLRGDPPKGAKKF
EAITDGFRYASDLVAFIKTNFHDICMGVAGYPEKHPEAPSMAEDLKNLKYKVDQGGDFIT
TQLFYNNQLYFDYVHKLRSMGVTVPVLPGILPVLNVNQVKRFGISLPQKLERQLLEVPED
KAAQRQIGVAWAVDQIAELLDNDAPGVHLYIMNMSKSALGILEQLKARGYFAD
>I5B6B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacter postgatei 2ac9|TrEMBL
MKTESRLEKVLASGQLAVTSEVGPPRGCNVDVIKEKANMIKDYVDGINITDNQTAMVRMS
SIAGGIVIKQMGLDPIIQMVSRDRNRLAMQSDILGAYALGCNTMLCLSGDHPQFGDHPMA
KPVYDIDSINMIKMVKDMRDEGKFQGGADITEPPKMFIGAAANPFADPFELRVMRLAKKV
AAGVDFIQTQCIFNTAKFEEWMKQVVDRGLDEKVAILAGITPMKSLGMAKYMKSKVPGMD
IPDEVIDRLAGVDKEKQAEEGIKMAIEQMQRLKECKGVKGFHIMAIEWEQKVPELVKGAG
LYPRPEV
>A0A2E8M7Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibacillus sp|TrEMBL
MQGTTNIAEVLGQEKPTVSFEFFPPKSAAASERLFSTIHELKQLNPSFVSVTYGAGGSTR
ERTHKLVLRIMEETTIPAIPHLTCVNHSXEEIEGILSGYADAGVPAVLALRGDPPGEDIE
YNRNQDAFPYASDLVSFIQGFNQEAKTQQKGFGIGVAGFPEGHPDTKNRLKXMDXLRQKV
DAGADYICTQLFFSNYSFLDFRDRCRLAGIDIPIIAGIMPITTRSGMERMADLAAGVHFP
AQLQRMLQGANDDPAAFETAGSDYATIQCRELLSEGVDGLHFYTLNKSSATRQVATELNL
GR
>A0A4Q8AFJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zhihengliuella halotolerans|TrEMBL
MTEHAATAPALSYELYPPRNEQAKSTIVDVIAELEASAPDYVSVTYNGTPERRRASVELI
GHLIEHTRLRPLAHLTCVGETRESLDRLVNHLVALGVRGVLALRGDKPEGDDPSSHGELP
FARYLVELIRDVENRRSASLAAGRLAIGVAAYPKRHPESPSFRHDIEVLLAKERAGANFA
ITQIYFDRTDYANLVRQARAAGVTIPIVPGIMPVNNERRLLRLCELSGLAPDEELRSRLA
GASTDAERHRIGVGHAAELAQAAFDDGAPGLHLYTFNDARSPLDVVDALQLTGAGTADAR
EGAEYGDANALQAAAHLAHA
>A0A5C4WA70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides albidus|TrEMBL
MTTGAGRSLGEIIREGGRSFSFEFFPPKDEAGEAQLWDAIRALEPYAPTFVSVTYGAGGS
TRDKTVAITGRIARETSLTPMAHLTCVGHTRDELESILDAYVAEGVTHVMALRGDPQEGP
RADWTPTDGGLNYAVDLVDLARSRGGFRIGVAAFPEGHPSAESLDADADVLVAKARAGAE
FAVTQMFFRASDYFALVERVRERGVDIPILPGIMPILNLAAIRRQGELIGTSVPDDIVER
ISAYDGDPAAVRAEGIRLAAELCDELLAGGAPGLHFYTLNRSKATLEIFEALQIRV
>Q3A3T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophotalea carbinolica (strain DSM 2380 / NBRC 103641 / GraBd1)|TrEMBL
MHIQDIFDRYETTFSFEFFPPKTDKAAERLYETIRQLESLHPHFTSVTYGAGGSTRERTH
DLVMRIHESSSLDPIPHLTCVSSPEQEIHQILKRYAEAGISNILALAGDPPPDMPHYDRS
QDAFPHAADLVRFIRKFNDEGLHPDKRGFGIGVAGFPEGHPTTPNRLLEMDYLKAKVDEG
ADYICTQLFFDNRDFYDFRERCELAGISIPIIAGIMPIASVEGMKRMAELAAGARFPAPL
LRAVDRCQDDPESVRRIGIHWATEQCRDLLDNEVRGIHFYTLNNSDATRQIFQCLGLQNH
K
>A0A669EW92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oreochromis niloticus|TrEMBL
MVNQVQRGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQSKEKITGYLAKAKHLGLKNIMALRGDPVGEDWEEEEDGFNYAID
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNY
GIQQAVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELQNEESVFEVFTSYITAQPNHCGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVNVSFLGNVKPCLVLLND
>G9YLB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor plautii ATCC 29863|TrEMBL
MMDIRTYLSQGKPLLFDGAMGTYFAAHPGRAEERCERANLTRPEEILRIHRAYLQAGCRA
IKTNTFAISGDLSDGNDETACDIVNAACHLARQAAQPYGAYVFADLGPAPRDHSRAPADL
YQTQAQWFLEQGVTHFLVETLSGDEGLPELAGWLKEKNPDAFLMVSFAVDHSGMTSAGRL
GSELYRFASELAGVDAVGFNCVSGPRHLLKYIQTLELSDKPLTVMPNAGYPTVLGRRTVF
GGQPDYFAGQIAQIVQAGASIVGGCCGTTPEHIAQTAQALKEPLPKCTVSAPKKLLKPAA
NASNSLWEKLEAGKRVIAVELDPPVDDDSAGFWEGVQALRGSGADAVTIADCPIGRPRAD
SSLLACKIKRDIGIEPLPHMTCRDRNLNATKALLLGLSMEGVHNVLVVTGDPIPTEDRNE
VKSVFNFNSRKLARFVHMLNENTLRTPFRIYGALNLNARNFDVELRRAQEKEACGVSGFL
TQPVLSAEALDNLKLAHKTLRGKILGGIFPVVSHRNACFLNNEISGMRVCDEIIHLYEGK
DRDAAEALAVTVSTAIAKEIFPYTDGYYLMTPFRRVALMEHIIQNIQQSCIS
>A0A8J3NF29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catellatospora bangladeshensis|TrEMBL
MTLRAPSTMPGPRPTVRELLSSGAPTFSFEFFPPKTADGERLLWQAIRELESLQPSFVSI
TYGAGGSTRGTTVQLTERIATETTLLPLGHLTAVNHSVAELRHVIGHYSDAGVRNVLALR
GDPPGDPQAEWVAHPQGLHYAEDLVRLLKESGDYCVGVAAFPEKHPRSPDHATDVHHFVR
KCRAGADYAITQFFFDWQDWARLRDAAAGAGCHVPIIPGIMPVTNVSQIERMAQLSGAAF
PADLAERLRAVADDPRAVRAIGVEVATELSAKLLAEGAPGLHFITLNRSTATREVWQRLR
VGATV
>A0A850BSM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MPIFTPGRRWQPPYLPFKREPLNRRALAALEKAIKGPLFGCRMCGNCLLQETAFICPMEC
PKGERNGPCGGSTKEHCYVDETRPCIWYKIYERSFAMGREEKLLEVLPPLDWDKVGTETW
GDVFGRVREIGAGKVFSGLLFKPAEVRYKTWDDIFEPIREPEWWQGDNKYHAPKYTEPVS
ELERRLKAGEFVVTAEVAPPLTVKTDKLFKNIQMVKPYVAAINFTDNPSATPRMSSQACS
KMAIEHGAEPVMQIAARDRTRVGLQSEVMGASAMGIRNILCLSGDSMKMAPSPRGRMDVI
DIDSIQMLWVLRRMRDEGRYMDGREIKFPPQYFLGAAASPFASEPKFQALREHKKVNAGA
QFFQTNLVYDVEHLEIWLNELAKRNILDKVFILIGITPLKTFKMAKYMNDEVPGVFIPEP
LMKRMEAAEKAGNAQEEGVQIALELIEKIKKFEGQGVNGLHIMAVGWEEIVPRIVTEGGV
LPKGFHQPELEKVPA
>A0A7W9QLN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQHH
RFEAAPHLSCVGGSREEIRELLKLYRAIGCRRLVALRGDLPSGMGHPGDLRYAADLIAFI
RAEHGDAFHLEVGAYPETHPQANDALSDLRHFKAKVDAGADAAITQYFYNADAYFHFVDA
VRKLGVQIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAEAIRDFGADVV
ATLCQRLIDGGAPGLHFYTLNLAKPTASVLARLRGAIAAG
>A0A1B1KY39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia inhibens PRI-2C|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLDAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGGGKPDMYATDLVRLLKEVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAA
>A0A173X3L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sarcina ventriculi|TrEMBL
MRISEIFNKKEVVISFEIFPPKPNGDVNKIYNTLDELKILKPDYISVTYGAGGSFINNKT
IDLASKVKNEYNIESVAHLTCIKSTKKDIDKILKLLKNNNIENILALRGDVTGNCTCGDF
KYASDLISYVKMYNDFNIAGACYPEGHPACVTLDEDIRNLKLKVDCGVNNLVSQLFFDNN
IFYNFLDKAYSANIDVPIQAGVMPVVNKKQIERIISLCGATFPKKFMKIVDKYEYDAIAL
RDAGIAYSVEQIIDLVSSGVKGVHIYTMNNPIVAKSIINNISSIVSCINKRSIDEFGRN
>A0A436M9M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.AU.002.02.1.1|TrEMBL
MNQFRFSRRPDIGDKVRFSFEFFPPKTDEMEARLWET
>F5VYE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus infantis SK1076|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFEIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQS
>A0A2D8K9C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiaceae bacterium|TrEMBL
MSESTETRGRKRAIDFSFEFFPPKTAEAEAGWWRSVEELAAYEPGFVSVTYGAGATSQAP
TYAAVKRLVDETRLQTASHLTVVKAGKGEVDDVIRRFRDAGIRRFVALRGDPPGGIGTAY
SPHPGGYANAAALVSALKAIDDFDISVSAYPEKHPESADRAADVAMLKAKAENGADRALT
QFFFDNDVFEDYLNDVRRAGIAIPVVPGIMPIQNLAQLKRFAAMCGASVPAFVERRFEGL
DDDPDGRFEAAADLAAEQVQDLVARGIADFHFYTMNKSKLMTAVLDRLGIKPGDTLSDAV
PERMRA
>A0A0Q6Z9T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afipia sp. Root123D2|TrEMBL
MSETSAQARTGSRASRLPAISFEFFPPKTEEMERSLWEVINRLAPLSPNFVSVTYGAGGS
TRERTHSTITRILGETSLTPAAHLTCVDATRASVDEVVDRYHEVGVRHIVALRGDPSSGI
GATYAAHPEGYQSSADLVAAIRRRHPDIEVTVSAYPEKHPESRDFDADIDGLKAKVDAGA
TRAITQFFFDNDLYFRYLDRVRAAGITIPIVPGILPVQNFKQARSFAQRAGASLPDWLAA
KFDGLDDDAETRKLVAATVAAGQVQKLAKHGVENFHFYTMNRADLVFAISHLLGLRPNGA
RKAA
>A0A4Q3I794|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiaceae bacterium|TrEMBL
MDTPAAKAPFKLSYEFFPPKSDEMQTQLWETVDALAAFKPEFVTMTYGAGGSTREPTLAA
VQRMINDAKLQTAAHLTCVDAAREEVKSVVEEYRAAGVRRIVALRGDSSAGVGAAYTPHP
DGFSDTADLVRMLVEYGDMDISVSAYPEMHPESPSMAADIDTLKRKADAGANRALTQFFF
DNEVFERYLEAVHAAGITIPIVPGIMPIQNLTQLKRFAGRCGATVPAFLDARFEGLDDKP
DDRAKVAADVAAEQIADLMRRGHDHFHLYTMNRVPLVSGVLERLGRHPDKDANVGNAA
>A0A0L6V932|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia sorghi|TrEMBL
MKISQKLAAAESENRISWSFEYFPPKTDNGLTNLYDRIYRMSQLGPIFIDITWGAGGSTA
NLTTEFVKTAHEHFGLETCMHLTCTNMPKEKIDNALKEAYEFGCENILALRGDPPKGSSE
WTATEGGFEHAIDLVRHIRAGYGNHFDIAVAGFPEGHMNSGLTKEQETQYLKEKIDAGAN
FIFTQMFYDVDIFINWVKDIRAAGITVPVIPGLMPIQSWAQFKRVTNFHHTIVPQYFLDK
LEPIQSDDQAVREAGTKLVADMCRKILNSDLGIRILHFYTMNLERGTKMILDELNLNPSR
DITNPLPWKMSLLGKRRSESIRPIFWANRAKSYLSRTETWDEFPNGRWGDSRSPAYGELD
GYGVNINSATMETLKALKKFPTSLEDLARIFANYCGARFPGEEPVKYLPWSDIPLSEETN
KIEDVLVKINKRGFLTINSQPAVDGAYLEFFCCPEKFQSLTERLEKDPDVTYYAVTRTGD
LITNNTRPGPNAVTWGVFPGKEIVQPTIVELVSFIAWKDEAFELGHQWAELYKELAPESC
QFIHQIMDSWYLVNIVNNDFRKSNDDSDNSTLFQFFGPEPVIVHDEQDPSHNGVHHPNGF
PKTNGSTINGINGDLKNLAV
>A0A088NA81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Baumannia cicadellinicola|TrEMBL
MSLFHVYQQEVLNQNLAELQGNINVSFEFFPPRTSQMELSFWNSLDRLSQLQPIFVSVTY
GANSGERKRTYSIIKEIKERTGLEAVPHLTCIDASQPALQEIVQEYWRSGIRHIVALRGD
LPPGCNRQAMTMYGLDLVVLLKTVGDFEISVAAYPEVHPEARSAQSDLMNLKRKVDAGAS
RAITQFFFNVESYLRFRDRCLAAGIDTEIVPGIMPVFNFRQLQRFAAMTNVKVPHWMSVM
FDGLDQDIETSKMVGASIAIDIVKILSREGVKDFHFYTLNRDELTYTICHTLGVRPKIKN
KPVVS
>A0A4R0WC56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIEGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFLGTQG
>A0A143ZU99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacteriaceae bacterium CHKCI005|TrEMBL
MSIAQLFETKSTVFSFEVFPPKRTSPIETIYSTLDELQELHPDFISVTYGAGGNLADNST
CEIASIIKNHYHIEPLAHLTCVNSTEQEIKEVLGRLKQNGIENILALRGDISPDRPPKTD
FAHASDLISFIKKQGGFHVSGACYPEGHIECDSLVDDVLHLRQKVDAGAEHLVSQLFFDN
DSFYRFVERARIAGIQVPIEAGIMPVVNKKQIERMVSLCGASLPPKFTKVMSRYEHNPQA
LRDAGIAYAIDQIVDLVSNNVQGIHLYTMNNPYVARRISESVSSLLRA
>A0A7V1W060|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTAVPTALAAARAAGRLVVACDVSPPRGPGLADLTRFRALTRADFLCCAYLPGRAVRLEA
AVMAFLLKRELGVDAIVNLATRDMNRLALSAHLLGIAALGLENVVVLRGDDFPDRDAGRV
RAVHDTTPSELIALIARLGEGRDFRDTALMAPVSLCPGATMDFSRDFTREVRLAARKARA
GARFFLTQSIYDDTLPERFAAAYRAATGADLVAPVLWGVPVLAPGSLAFGAVPDAWRRDL
GAGRPGAEIALEFIHALRARGVEAIYLIAPILRGGERDYAAAGAVLAAL
>A0A7V1W097|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTTAPAPRRVLGPVARAGERTDRPRVSFEFFPPKTEQMEENLWAAIKRLAPLDPAFVSVT
YGAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRAEVDEVIREYWETGVRHVVSLRG
DPPPGEGGIGGVYVPREDGYKNATELTAALTSIAPFNVLVGVYPEKHPESPSIEHDIEVL
KAKVDAGATLAISQFFFDTDAFLRFVDKVRAAGITIPIVPGIMPVTNFKGLVKMSKACGT
AVPGWLANIFDGLDEDADTRRLLACSVAAEMCAKLQEQGFSDFHFYTLNRADLVYAICRV
LGVRETAPSPISAEAAA
>A0A7C7TW06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MPPVESAFVNSLRSGIVLADGGIGSLIFQLTGRLASNEFVYEALNLRNPALIKGIHSSSL
AAGAMVLTMNTFAANSTELSLAGADDQTTEINRTAVQIAREAISEYQIEFSQQDNRFYVI
GSIGPGGDDLEAYESQINALIDSHVDALLLETFTDIDLAMQITESISNRSDAPPVIVHAA
LDPGVGEKRNWPMEPSEFATRAAAAGATVAGINCVAPWAAADFVESAKQASVVKSGELLL
SAMPNAGGFERIGHRFLARANPEYMGTLARQLGDSGASLVGGCCEVHPEHVREMSAYLKS
RSSSVSVGASESGTPTDVRDDHDNERRKKNGEFTRKILDGDFAISVEMVAPTGADPKALD
LRARMVREFVDEGLADAVDITDGSRGLPLVPPGDLVELIRRRLGWQDEDEIEFIAHFAGR
DLNTLAVQSRLMGYHLRGIRNVLFITGDPPKMSPTYPRSSAVFDMNSVQMLRATAGRLNR
GRDFGGNPLGGGLESGTQFTVGTGFEPEAINMALELDRLQAKIDAGADYVMTQPTFGDSV
LSAVEGFRNSISVLPGVMVLRNAAHAERIAQVPGMNVPATVIDQLSRFDDPADQARVGLE
LAVDQAQRYRSEGWAGIYLMSPASMGAAKPLLKTLAE
>A0A800GAK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MPEKTTGGAALVKITEGCFEATGHTSIICDFSPPRSGDTAIVDESQIDANFISVAYNPGR
AVRTNSVMLAAAIQRTGKDAVFTMATRDMNKLALQSQLLGAQMLGLQNVVVVQGDPFGKN
DQPRVASVNDYQPTGFISSIAEMNQGRDFEESNLRTPTDFCVGATVDLGKPIEEEVKLAV
RKVRAGAKFLITQPIFNVDHVGRYRESYGYHADKAGTHPVYFGLQILEKDGVLFSSVPES
VKAELESGRSGVDIALELYEKFQAARLNNIYLMPPIKRGGARNYEATKEFLRKAKQT
>A0A7V2LQG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSLQPLFESGKFVVTAEVGPLKGTDTTELEEAAELLRGKIDATNVTDQQSSVMRLGSLAV
CYLLKEKGLDPVFQMTCRDRNRLALQSDLLSASVLGIENVLAITGDLPLLGDHPQAKPVY
DLDSVQLLWVIKKLNEGFDMEGNELKGKPNFFPGAVVNPGADTRAALELQLLKMEKKIEA
GARFFQTQAIYDPTAFAKFMKRAGAFKVPVLAGIIPLKSAGMARFMNKNVAGVFVPEEMI
EKMTAAEDKTRMGIEIAADLIKQLKDICQGVHVMAIGWEKKVPEVLEAAGL
>A0A7V2RF63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSKLKDKLSSREFVVTGEIGPPKGVDISGCLHDAEQLRDYVTAINVTDLQSAVFRIGSLA
VSCKLVERRLEPIYQLTCRDRNRLALQSDLLSAWALGIENVLCLTGDHPAMGDHTEAKPV
YDLDSVQLIKAASTLNQGQDMSGHELDSKPSFFLGGVVTPGADPVEPQVIKMKKKIEAGA
VFFQTQAVYEPDKLEDFMNRVQGFNVPVIAGIVILKGAAMAKFMNQNVAGITVPDSIIEE
MSDTPKEDRKKQAVEITARIIRQVKPLCQGVHIMPLGWDELVPQVIKEAEL
>A0A6J2XVZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sitophilus oryzae|TrEMBL
MSPRLITRSPVTLALNKKIKTWVNKSVALKSASDKRTDNMSGKYSILETSQNRISIEVSP
NNNFNAKLLGELGPHFISVTWLGAKYLQLPNHQIPTVVLAQNLNKLKCPVLVHLPGRNLK
KERMLEILNLLKNSGIKHVLALQGDWVHVLEKDDTKVDFPYASDLVSFIKENFGSEFCVG
VTAYPDLHPHCEDLERDLDYLKKKISLGAEFILTQAVFDFDVLENYVKSCRRHGINVPIF
VGVFIIKSYQSLKNMAKWCEFKFWISYPPPGAGSSSSSKDKEKEKLEDEKKPLSKEQRQQ
EYDAAIKEHHRSQREQWEIRQLDNDLLQQRQSEREREREQKELAEQRLLLVDEQDELNQQ
PP
>A0A8C8CGW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
MVNQVQRVEDTWRTCSKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGFVFQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRN
YGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVNR
RGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEALR
QDCVDAQIW
>A0A7D8E9X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klenkia terrae|TrEMBL
MTHGPCGGVGEDGSCEVAPVPCAFLPLPTVAWAGPTAVRTTPEPRLLALMRQRPVVVADL
PAVALDRGSLQRAADTVVGTVDAVLLGDHGGARVQFSPTYRASLVQARGLPVWQGLNCRD
RNRVALEGELAGLADLDVGAVHCVTGDHTATGDRPDAQPVFDLDSTQLAAAARAAGLLVS
VGETPHGPPAERRPHRLVEKVRAGADVCFVNHAGSVQALRAFVEQATDAGADVPFVACVA
VATDPGSAAQLRRFTGLRLPEGYLAGIESARDPRRAGIAAAVALAQAYLSVPGVRGVDLS
GVPSPGTELTTATALAEIGRALS
>A0A7Z6ZGE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis pv. eucalyptorum|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A352B6H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MTNKFVELLSSQTLLADGAMGTQLYEHGLFLNQCYDAANLTHPQLVQEIHEQYAEAGAEI
LETNTFGASRQKLTPYGFGDQVEAINRAGAAIARKVAGKTLFVAGAVGPLPLRLAPLGKV
SAASACAAFTEQMRGLVAGGIDLFCLESFGLITEILAALEAAREVAPGLPVIAQMTVDEN
GYTSHGTPAEEFARALDQAGAEVIGVNCSVGPAPMLETIERIAAVTGRPLSAQPNAGLPR
NVDDRLIYMSSPEYFAEYARNFVRAGVKIVGGCCGTGPAHIRAMRSAIRSLVPGRTTIHI
EPREQLAGAATPPPLAARSALGAKLAAGRFVTSVEITPPRGADASGVLESCRTLKGAGID
IVNIPDGPRASARMGAQHLAILIERAVGIESCLHYTCRDRNLLAMQSDLLGLAALGIHNI
LIITGDPPKMGDYPDATAVFDIDSVGLTHLAAATNHGLDLGGNRIGPPTSFVIGVGANPG
ATNLDRELDHFRAKVEQGAEFAITQPVFDPQILLRFLDKIEPFRIPILAGIWPLVSLRNA
EFMAHEVPGVIVPDVLVERMRVASARSKEAARDAGLAIAREALAAVKDRIDGVQVSAPFG
RVELALPVIEAAADRL
>A0A7X3QRQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKSGSRLERVLRAGHFAVTAELLSPDSADPQAVLDHAQVIGDSCDAINATDASGATTHMS
NVAVAALLRRAGYDAVVQLACRDRNRIAMQGDLLGIAALDVRNVLCLTGDGVGTGDHPEA
KPVFDMDSITLLRIARILRDKGQFLSGRPIDSPPRLFLGGASNPFVPPYDFRPLRLKKKI
EAGADFIQTQYCFDVPRLRSFMERVVDMGLQERAFILVGVGPLRSARVAYWMRENIPGVV
IPDAVIRRLLGAGKRSRTEGKRICIEIIQQIKEIPGIAGVHVMAYRQEHLVPEILDEAGL
LPRPEPELFDGIHASSADVVESNRC
>A0A832C8X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MVGLDFQQALEGNQFVITAELAPPKGTDVSRMLACAERLKGRVHGINVTDNQSAVMRLGS
LAACHLLKERGFDPIYQITCRDRNRLALESDLLSAAVLGIRNVLVLTGDHPNAGDHPEAK
AVYDLDSTQLLQVINRLNQGRDLSSRSSRGKPLVNGATLAGGTNLFAGAVVNPEANPMEP
QIWRFSQKVAAGARFFQTQAVYDLERFDQFMGYARELGAKILAGVLLVRSAAAARYVNEH
VPGVVVPERVVKELESSANPLEAGIRMAGQQIRYLRERCAGVHIMAIGLEEHIPAVLDEA
GI
>A0A523ZHX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MANSLFEEKLNSNEFLVTTEIGPPKGADVSEMVHHIDLLKDNVDAINITDHQSSVMRFPS
LGGCLLVKERGGEPILQVTCRDRNRLALQADLLLAYSRDICNVLCLTGDSIDVGDHKEAK
PVFDADSVQLLRMIRTMESGKDMSGEDLKGALKFCIGASVHPEADFIEPQLIKFEKKVAA
GAQFFQTQGIFDLASLRRFMQYASQFDVRILAGIIVLASARMARYMNDNVPGIIVSEAII
DELAGVEKGKGLEKGIEIAARLIKTIKEENLCHGVHIMAVGNERIVPEILEQAKLPSMPT
KAQ
>A0A1Y2WV14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Daldinia sp. EC12|TrEMBL
MHIHEMLADAERTGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDITWGAGGRIA
ELTCDMVVQAQAYFGLETCMHLTCTDMGEEKINDALRRAYKAGCTNILALRGDPPREKEQ
WVATDGGFKYAKDLVAHIRKMYGNHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDMGATF
IVTQMFYDADNFIRWVKKVRERGITIPIIPGIMPIATYASFLRRANHMNCKIPEEWMAAL
EPVKNDDAAVREVGKTLVAQLCRKIMSAGIVHLHFYTMNLAQATRMVLEELDWMPTSNRP
RKQALPWKQSLALGRREEDVRPIFWRNRNKSYVSRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKRWGEPKSIRDIASLFVRYIQRDLPSLPWSEAPLTSESDSIKDDLIK
LNERGLLTINSQPAVDGVKSTHPVYGWGPPNGYVYQKAYLELLVSPDLFPEIVRRINANP
DLSYYAVTQSGKLSTNTPSEGPNAVTWGVFPGKEIVQPTIVESTSFLAWKDEAFRLGTDW
AHCHDANSPSRILIEKIMNEWYLINIVNNDFHQSRTIFELFDGLTAKDIDVPVTSVSGEQ
NGSHETNGN
>A0A2E1D140|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MLELSVEFFPPKTGEGISRFNKAADELVPVGFGFASVTYGAGGSTREGTLTAARELKKRF
KEGVPHVSCYGSDKASIFELLKTYSNDGFSRLVVLRGDLPSGYGGLGEFKNAVDLVRFVR
REFGDQFKIEVAAYPEKHPQSTSFEQDIDYFVEKVXAGADGAITQYFYNSDAYFSFVDEV
QSRGVSVPXVPGIMPITNFSQLARFSDSCGSEIPKWIKHRLSDFGDDRVKIYNFGIXVVT
RXCKDLIRAGCPGLHFYSMNQSXPIIDILSGIEFTTDG
>A0A523Y7V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKAGTNLEKVLESGRFAVTAEAGPPRGAAASVIQRKGELLKPCCDALNVTDNQTAIVRMS
SLSGCILLKQLGTDPVMQIVCRDRNRIAIQSDVLGAIALGIGNILCLTGDYQSFGDHPTA
KSVFDLDSIQLVQTLKLMRDEKKFLSGENISGEVPLFIGAAENPFADPFEYRAMRLAKKV
RAGVDFIQTQAIFDVDRFTRWMEMVTDRGLDKEVHILAGIIPVRSVGMARYMRDKVPGVS
VPDEIVTRMENGKDAREEGLKICLEIIDQIKDIPGVHGIHIMAVGWEDIVPTIVERAGLL
PRPLM
>A0A1Y4SDS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp. An131|TrEMBL
MGMLEKALESGKFGVTVEMAPPKGYDFTEQMEAAELLKGKVHGVNVTDMQSACLKASSLG
LCIKLKQAGLDPIIQVTGRDRSRMGIMGDMFSAAAFGIDTMLALTGDHPTVGDCKQSKPV
YDLDSVGILHMLTAMEATDRDCGGNEIEGGAPVFYKGAVVTPVYDPLPLQINKLRQKVEA
GAQYIQTQGIFDIESLKRFMDEVDKANIHTHIMAGIIPLKAAGMARYMNENVPGIAVPQD
MIDRLAAAAAEGKEKGVKGLPTQLGIEMAAEMIAKIKDEGICDGVHIMAIGAEKNVPKIL
EKAGLTIE
>A0A2E1ERZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSIFPSRSKLTEDLRNSRRKCFIACDFSPPKLDNPQGLKLATSLNPDMFSVSYNPGQSVK
LNPVFASFWIQNETKISSAFTLATGNMTPRCLEKLLLNAHVLGLTNAVFVMGDASSKTIS
ATKALELTARMNFGLDVRNNQLDIPTNFCIGSTIDISKNWDHEISLTKKKIDSGAEFFLA
QAQFDISKVVQFLESYRDKIGTHIEIPILWGVQMITKGSSSFSSIPDDMKRDLDLGRSGL
DIALEIFDQYFAYGIDSFYLLPPFFRTGKRNYALAEELISALTSN
>A0A1F8ZYQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_43_22|TrEMBL
MGLKDKIEAGEFTILAEMEPPKGVDVSVMLSNAKRVKDGVDAFVIPEMGNAVMRMSSLGG
AMVLQNEGLPTVFQVCCRDRNRLAIQGDLLAAHALGINTVMAVIGEDPSFGDHHQARSVN
DVDLFELIKAIDRLNQGKDMAGIELAGAPDFLIGSTTEAGAKGKSTEVEMEEMMKRVEAG
ARFLITSPIFDPSLLDPYKKRIDLRKVAVIPTVMLLKSLGMARYLVRNLPHLHISETIID
RIARAPDKVRECVQIATETVRELKHQGFNGVYLSTLGWENKLPEIIEGI
>A0A520PSI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MRIIEMYHNRPFVFSIEVFPPKTEEGMVNLQEKLRTFSLFKPDYISVTYGAGGGTRQNTQ
QLAGFIGNELGIEVLAHLTCVSHTRKDVSLLKEQFLSEGVENIMALRGDSPTTEKTFEPM
SGGYRYASELIEDLSRDRRFGIGAAGYPETHIDAISSKMDRYFLKQKIERGAEFVISQFF
LENQKFLNWRDQLYREGVRIPMIPGLICAQSSGQIQRFAKMCGCMVPSDLIKNLERFEGN
AADSLRVGLDHAEKQLSGLIKEGITGVHLYALNRSEVVNALGPTMVGLMSRTDLQSSLEN
DGRLGF
>A0A5C6U7E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingorhabdus soli|TrEMBL
MTPSFTDLEEASRALGAPMFADLSGDIAVSFEFFPPASDAMATKLWSAIETLAPLGPRFV
SVTYGAGGSTRERTHETVKRIVAETDLTPAAHLTCVGATRAEVDEVARGYWEAGVRHIVA
LRGDAPDGQAYAPHPQGYANAADLVAGLRKIADFDISVAAYPETHPDAGDSAVDLDNLKR
KIDAGANRAITQFFFTPECFFRFRDAVAAAGIDAEIVPGILPVSNVAQTRRFAGLCGTAI
PGWMDRLFEGLDDRPDARKLVAATLAAELARRLYAGGVREFHFYTLNRAELSYAICHLLG
LRPKPDANAALSQDQAA
>A0A5R1P4F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT1-66-1|TrEMBL
MTAPTPNACDARPAFSFEVYPPKSVAAASALTRTIDHLAAAGPEFISVTYGANGSSRNSS
LDVLRYIKDHTSVDAMAHLTCVGSSHTEASRLIREFLDAGIRSFLAIRGDAPQGADEGDT
PFLGDLHSAGELVQLIHRVQIERVPYIETVIPGLPGARGVKTERSKVRIGVAAFPNGHPN
SRSVTQDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLLPILPGIMPVTSPN
RLRRILQLSGEKLPAELSIQLEVEPTDEGQRQIGIDYAVRLGQDVLAGGAPGLHLYAFNQ
HDTVLKVLEGCGALPVPAAMP
>D1YM30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella parvula ATCC 17745|TrEMBL
MTLREKHQQGQFTITVELDPPKSSSAEKTFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDSPTNFYIGATGNPGAPDLEIERQKLAAKIQNGA
HFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
MEKGGKEAGTEIAIETLEQIKKMAAGVHIMPLNDIDTTLYIIDHV
>A0A3N5XQ84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
SLHLDMHIGVAFNPNLTDISSQVKRLKRKIEAGAEFVMTQPMFDANKVLSMCDAVRDLNI
PIYLGILPLVSKRNAEYLHNEVPGITIPDTVRARMDIEDKMKAREEGISIALEIMRATKN
AVDGFYLISPLHRYEISAAILKEL
>A0A0B5FR32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geoalkalibacter subterraneus|TrEMBL
MSKLAEKLIAGEFVVTAEVAPPKGVDLDGVLATAACFPPEVVAVNVTDNQGANMRMAPLV
VAALLHQGGVEPVLQMTCRDRNRMALQSDLLGAAAFGIKNLLLLSGDHPRFGDHPHARGV
FDLDSVQLLQAADRLTAGQDLAGRPLAGSPAFFGGAAVSPQAEPFELMFQKFRKKVEAGA
RFFQTQAVFCEAPLTRFMEQAAPLRVPVLLGVLLLKNARMARFVHEHVPGVRVPEHLIDR
LDGAADPLEEGVRIARETVRLARRHCQGVHLMTLGCEDRISEILC
>A0A6N9K1P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. BIOML-A2|TrEMBL
MNILESLKDKLLVADGAFGTCYVGMYGEQGTVAPELANMRHPERVLEIHKEYVKAGAGLI
RTNTFAANTASLDADTDYVISNVRAAVKLAKQAADGEAGTDHKKVYIAGDIGPIPADAGL
TLNERVSQYKLLGEAMQDMGVDIIWFETFPEFNVLEPVVKHLKARKDTPVMVSFCVNQFG
YSNCGFSARALLSQVAGNQDVDCVGFNCGVGPYHMLQLLKKLDIDCGKPVSVMPNAGYPK
FTQSRLVFNDNKEGFIDKIQDIAALGADIIGGCCGTNPEYIHQIMERVKTGDIAKAAKIH
VEKVQADSAVKDNFLKGRLERGGAATKNADGHKHKLIAVELAPPVDVNDQKLLDAAHILK
QSHVDVVTFPDSPSGRTRANSILMAEKVHKETGLRVMPHLCCRDKNAIAIRGSVLGAQLN
GIKDFLVITGDPVPVMFRQTTRSVFNFDSVGMMKLLQSMNEEVFSGDKITYGGAINQNRL
NTKFEIDRIKRKMEAGAEFFLTQPVFSREQAQILRDMKAETGATILVGIMPLVSRRNALF
MKNEMAGIEIPDEIIERYSENATRQEGEECGIQIARDILEYTSDFADGYYFSFPFNRVHM
LAHIVD
>A0A512HEE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciceribacter naphthalenivorans|TrEMBL
MATEEQESVTTRRLRFSFEFFPPKSEDMADQLWKTVEALSLWTPDFVSVTYGAGGTTREP
TLSTVKRLISETALPTASHLTCVGATKDEVRQVVEQFRSVGVKHFVALRGDPQGGMGSAY
QPYPGGYSNAAELVAGLREMGGFEISVSAYPEKHPESPDVAADIDMLKRKVDNGACRALT
QFFFDNDVFERYLERVRAAGISVPIVPGIMPIQNLTQLKRFASMCGATIPGFLDDRFAGL
DDQPKARAEVAAAVAAEQIEDLARRGISDFHLYTMNRSALVTATLGNLGLRPRALADDGA
GAAA
>A0A2S0UYF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colwellia sp. Arc7-D|TrEMBL
MKNGSELRARYNDVNRGVYFIGTTPPKSDTPIDQVSTIADKLLERVSDIDFDGLIVYDIQ
NEDSRTSKPRPFPFKSTHDPRLYSSLLQQKSNRPVITYKSVVQSNGDDFNQWANEAWHEY
GIRDIVLVGSPSQQNNISLPLGKAYETLVANENDFFIGGITIAERHANKGNEHAKLIEKH
QQGCNFFISQAIYNPQATIDMLTRYAIECQQQGIKPQRIILTFSPCGSMKTLEFIEWLGV
SVPEATSLRILNAERPLYESIRICSNTLVQILDAVLPYKVPLGLNIESLTNRKEEIDGSI
LLYKLLRSTMDNYLAKKELSGLFTD
>A0A1G2W7R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadaceae bacterium GWC2_58_13|TrEMBL
MSRLEQQLAAGQFVVTAEIAPPKGIDTAQALEKARLMANLSAVNVTDNQGANMRMSPLAM
AALLVRQGIEPILQLTCRDRNRMALQSDLLGAAALGLENLLLLSGDHARFGDHPKARSVF
DLDSIQLMQTVRGLTEGTDMTGKILHGAPRFFAGAAVTPEAEPFELMFQKFAKKVQAGTR
FFQTQAVYDVEKLERFMGEANRLGTPVLLGVLLLKSARMAEFLNRNIPGVRVPQALIDRL
ASAPVPLEEGILIAREMVGHARRLCQGAHLMTLGHEERIADILG
>A0A1H3MCS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. yr284|TrEMBL
MLPISFEFYPPKTDDQRSQLDKTAAKLRGFSPSYVSCTFGAGGSTLSYTPETIRRLRGKH
GLDAAPHLSCVGGTRSEIRELLALYREIGCRRLVTLRGDLPSGMASAGDLRYANELVEFI
RAETGDHFHIEVAAYPETHPQARDALSDLENFKRKVRAGADGAITQYFYNPDAYFRFVDD
VRASGIDVPIVPGIMPIANFSQLRRFSELCGAEIPRWIAQRMHAYGDDADSIREFGADVV
AQLCSRLIEGGAPGLHFYTLNLAKPTLSVLARIA
>A0A2P4XKW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora palmivora var. palmivora|TrEMBL
MKIIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMDEADIKKALDQAKDAGIQNILALRGDPVRGASS
FDECDRGFSHAVDLVRYMREKYGDHFCIGVAGYPEGHVESKDKKADIQYLKEKVDAGADF
VITQLFYDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTSFCNTYVPEEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRASETVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSSTSTPKERRAMWGEAPASKEDVRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
SANSAGFLTINSQPRVNGALSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
PSVQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEEGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSPVTSP
>N9EBI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus ANC 3680|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLRIVHQELQPLNPDFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIRQHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A2T2S6W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QH_10_64_37|TrEMBL
MKATEHFDRASEPLISYEIIPPKRGGSAEQILRVVEELMPFDPPFIDVTSHSAEVEYKQQ
DDGTWQRCVKRKRPGTIGLCAAIEARFGIDTVPHLLCKGFTREETEDALIELSYLGIDNV
LAIRGDDKGYEKSISGNRSRNEYAVDLVRQIQDMNQGRYLEDMMNAEPTDFCVGVGGYPE
THIGAPNLAWDIMRLKEKVDAGADYIVTQMFFDNEYFFHFVDKCREVGIEVPIVPGIKIL
KRKRHLRLLPKYFHTEIPEELAAEADAADPDDVENIGVDWAIRQTRELMEAGVPCVHFYI
MSSADTVKKVVEPLHEMA
>A0A374VZ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. OM06-36AC|TrEMBL
MKIASLFSEKTVFSFEIFPPKKTSPIETVYDTLEALQDLKPDFISVTFGAGGSGNGENTL
AIARRLKEHYGVLPMAHLPCIHYTKEQIDNILKQFQENGIENVLALRGDRVEGMEPAMDF
VHAADLISYIRSFGGFDIAGACYPECHPEAPNMDTDIRHLKEKVDAGASHLITQLFFDND
SFYDFRYRAARAGVNVPIEAGIMPVTNRKQIERMVTMCGASLPRKFTKMVQRFENNPEAL
QDAGIAYAIDQIVDLVTDGVDGIHLYTMNNPYVARKISEAVSGIIKAAPKC
>A0A143Z402|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus sp. ES5|TrEMBL
MKIREMISKGEPTVSFEIFPPKSSYALETVFDTLTELKDLHPDFISVTYGAGGTAQSNTV
EIASRIKKDFGIESIAHLTGCTSTKEGMKRTLTSIKDSGIENILALRGDIPQEKLADKNW
NPEYRYASELIDDIKAAGDFSIGAACYPEGHVDSINKVDDLKNLKRKMDHGADFMITQLF
YDNDLFYQFKEKLDLVGIEQPVIAGILPVLNIKQVKRIQEISGCNLPPKFLRILDRYAHD
PASLQEAGIAYAVDQIIDLLSSGVDGVHIYTMNKPDATRRIMENISCVRKAVCRKEPQR
>A4BSE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrococcus mobilis Nb-231|TrEMBL
MDNQDDKTKGGLVSLPKTVTDRSVPIYLEAVPPLLREGAAGIDAVLEKIDAIHGAVELDG
VNIPEIRQESSKSKKGERLKPFESRLEPRELAKRIQEDFGLDCIINRVVVHLARERQAEW
FRQAWEEYGIRRFVLVGGEKSGECYPGPSVPESNELVHRVIDDCELRVGNICIPTRAQEA
QRMARKLATGADFFTTQIVYHAREFTRLLDDLQASALPSRAPPTLLLTLCPVQSQRNIRF
LHWLGVSLSAELEAWLARDPERVAERSLQHLERMWIEIHRHWRAHHDRFPIGISLAPIGR
IPPMTTVQLARNLISMTDRAMIRRAGTERTL
>A0A424YE45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Syntrophonatronum acetioxidans|TrEMBL
MSSFRDSLGKFTITCEVGPLKGCDITEVVEVAEVIKGKVHAANVTDQQSSVLRLGPLVTS
HLLKDHGVETVYQMTNRDRNRIAIQSDLLSAAALGIENVLSLTGDYQSLGDHPQAKGVFD
LDSVQFLATVKTLNEGKDLSGNKLEGVPNFCAGAVVNPGADSEASYELQIIKMEKKAEMG
AKFFQTQAVYDFKLFEKFMKDVSHIDVPVLVGIIPLKTAGMAKFMNKFVSGVFVPEHYIE
RMAKAENKDKEGIAIAAELIKGLKDMCQGVHVMAIGWEKVVPDILAESGLL
>A0A1Q9RUQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. CNS-004|TrEMBL
MATVTTWDRTIMALQADLLGAHALGLHRIVCETGSPPLLGDYPHVDGVWDVDAIGLIELL
AGLNEGTDFYGLQLPAKTAFEIGTRINPGSRDLAHAAARARDKIAAGAQFLITRPLYDVT
DLERLLDAIGDDRPPVLAAVRPLTGFEEAEYLAHEVPDVHIPDHVLNALERAGTTGPEAG
LELAAGLAAAVGPLVNGLVIMPTSDPVPTVQRLLGT
>A0A1Q9S168|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. CNS-004|TrEMBL
MGLRRRICEGTGEFLLFAVTPPRQAASPERAEEIAEVTIERLRPLGLDGLVLYDIDDESD
RTSEERPFPFLPTMDPADYLARHLSALDVPAVVYRVVGKYPEADLRSWLLAQDAERVLSV
FVGASSGGKPVATSLTQARQLRAAVRPDVVLGGVAIPERHTRRGDEHLRLLEKQAGGCSF
FVTQVVYDANAAKDLVSDYRYECDARGVAPVPIVFTFSVVGSTKTLEFLHWLGVDVPRWI
QNELRHAANPLAASHEQAFATALDLIAYCRRLGVPFGLNVESVSIRRAEIEQSVSLAAQL
GRELNRSRGEGSGTPRS
>A0A562VB10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stackebrandtia albiflava|TrEMBL
MPGGAPAIIELLRTGEPVFSFEFFPPKSAKAEQVLWTAIRELESLQPSFVSVTYGAGGSN
RSMTVETTDRIATETTLLPMAHCTAVDHSVSELRNLIGHFASGGVRNILALRGDPPGDPQ
ADWVAHPDGVNHAYELVELIKSSGDFCVGVAAFPEKHPRSPDWETCTRHFIDKCRAGADF
AITQFFFDWRDWVRLRDATAAAGLDTPVIPGVMPVTSVKQIETFAKLSGAVFPAALAERL
HAVADDPVAIRAIGVEVATTLSEKLLAEGAPGIHFITLNKSTATREVWRNLRVPARMSG
>A0A4Q3AKG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium|TrEMBL
MSIDRDPSSPPLFADVAGDIDVSFEFFPPKTEAMEKTLWESVGTLSPFDPRFVSVTYGAG
GTTRERTHNTVARIARETPIAVAAHLTCVDATKAEIDAVAEEYWAAGVRHIVALRGDPPR
AGEKYATHPGGYENAADLVGGLRKLHPFEISVAAYPESHPDSPDAAHDLDNLKRKIDAGA
NRAITQFFFEADTFLRFRDAAAAAGIDAEIVPGIMPVMSFAAVQKMSAMCGTDVPAWMAR
LFDGLDDHPAARQLVAATLAAELCRNLYAGGVRQFHFYTLNRAELSYAICHLLGVRPRGA
AASVAA
>A0A1Y6FD82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Plantibacter sp. VKM Ac-1784|TrEMBL
MTTTEPACPRRTPFSFELYPPKTLDGGLALARTVEHLAAAGPEFISVTFGAGGSSRTASL
DVLRSIRTSTSVDPMAHLTCVGSTHAQASRLIKDFLDAGVHSFLALRGDPPAGAVEGDAF
LGDLGSAAELVQLIGRVSAEHEPYAEGSLVGLPGAVQLGRRHRPRIAVAAFPNGHPRSRS
TTQDLDTLLAKQAAGATLAITQLFFHADDYLAFAERARRHGVTMPILPGVMPITSPARLR
RVLELSGEALPSDLAIALEVEPDEAGRIDIGTDYSARLIRDVVAGGAPGVHLYAFNQHRT
VLDVLHRAGIPVHDDRPVRHPIPDPLTSKDAR
>A0A853EIN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces bowdenii|TrEMBL
MTYSADPHSAGRAPARPTVSLELFPPRPGRAAPATWSRIDSLLATAPDFVSVTYRPTFVT
DAAGQGAVGVRVVNEPNPAEQVVEHVLGTSTVPLMAHLTCIGYRRSDVVEIVTHFLGMGV
RRFLALRGDPPAGTAPDQVAGELPHADDLVRVIREVEAEYFGDGRRHVTVAVAAYPVTTD
HAQAIEVLAAKQAAGADLAITQVFYDAEDYAALCRAASYAGVTMPVLPGLIPLTDLGRLT
RLESLTGVPVPSGLRAALSSARGAELVGRGLDATLGLATDLLEAGAPGLHLYTFNRTRPA
LDIISHLRLGGILSGSAPDPRVREAIERGYLQATPGRGPSFLRGGHRRPPTGGTSPSGHH
HH
>A0A498ESX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halorubrum sp. Atlit-28R|TrEMBL
MSQNLFSIEFFPPKTQEGVEKLRATRAKLAALQPSYFSVMFGAGGSTQQGTRDTVLEIKR
EGHDAAPHLSCLGTSRETLRELLQEY
>A0A7Y0ATH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. S-51|TrEMBL
MAIDNRKEARGERLRYSFEFFPPKSEDMSDQLWKTVEDLLPWSPDFVSVTYGAGGTTREP
TLSTVRRLIAETPLRTAAHLTCVGATKEEVHRVVEEFRAVGVRHFVALRGDPQGGIGNRY
EPHPGGYANAAELVAGLRELGDFEISVSAYPEKHPESPDDAADIDMLKRKVDNGACRALT
QFFFDNDVYERYLERVRAAGISIPIVPGIMPIQNLTQLKRFASMCGASIPSFLDERFAGL
DDQPRARAAVAAEVAAEQIEDLVRRGISDFHIYSMNRSALTIATLANLGLQPNAISSKGA
AA
>A0A671X1A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sparus aurata|TrEMBL
MVNQVQRGDGSWQSCKSDSSGASNSGGESSKESSRCSTPVLDTDRSDRLRDKMRRRMESG
ERWFSLEFFPPRTASGAVNLISRRVAFIMSDSKDCYQTTAGHLFYYFFFYYIIFSRFDRM
GSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQTKDKISGYLG
KAKHLGLKNIMALRGDPVGADWEEEEGGFNFAIDLVKHIRSEFEDYFDICVAGYPTGHPE
ADSYEEDLRHLKEKVDAGADFVITQLFFRAETFLKFLDDCRAIGITCPILPGIFPIQGYQ
SLRQLVKLSKLEVPEEITEVIEPIKDNDAAIRNYGIHQAVEMCRVLMDSGKVPGLHFYTL
NREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDE
FPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLQMWGQELMNEESVFEVFTCYITSQP
NSSGHKVMCLPWNDEPLAPETNLMKEELEKVNRRGVLTINSQPNINGKTSTDPIVGWGPA
GGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGRNLTNAPDMQPNAVTWGI
FPGREIVQPTVADPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIINYIHDNYFLVNLVD
NDFPLENCLWQVIDDMFELLDAPTEPLYSGAVSE
>A0A094GG24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4517|TrEMBL
MADSPTTDKLTDKIAALPQDASYFSLEFFPPKTAMGSTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSKELVDDALRAAKEAGIQNILALRGD
EPRGEYKDALEEGKEGEDEFVWAIDLVRYIRKKYGDYFCVGVAAYPEGHADGSHPAEQSL
EHDLPYLVDKVQAGADFIMTQLFYDVDAYDNFEKVLRDHSSGAFKAIPIIPGLMPIQSYQ
ILRRTTKLSNAKLPQSIIDRLDAVRTDDEMVKRVGVDILAEIVESVKATKSRTKGPKGFH
FYTLNLEKAVAFILERANLIPSFTPVLTSDVFAVDDITDTIPLPQLLINGERKNRRQSSV
GSGPHNFVIIDREEASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNG
RWGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRPDITSIFVQYINGTLSALPWSDE
PITAETNLIKDELVKLNQKGWWTIASQPAVNGARSQDEVVGWGPKGGWVFQKAFVELFVP
TSDWARLKQLLDGNAEVSFLAQSASGEFLKSKLDLGPGEEGSETNAVTWGVFPGKEIVSP
TIVEEVSFRAWADEAWQMWEEWAAVFGKSGEESRRFLDGVAKDGWLVNVIWHDFVGMCKA
KEGRSEEEGYKGLWDMLIEA
>A0A4R8DX35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. VKM Ac-2566|TrEMBL
MANGLPSTLPGGAPTIRELLASGDRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWVAHPEGLNHATELVELIRSLGDFCVGVAAFPDKHPEAASLEADAQVLAA
KAQAGADYAITQMFFGADDYFRLVDRAAALGCEIPVLPGIMPVTNIKQIQRMAELTGMAL
PTAVTDRLLAVEDDPAAVREVGVEIATELCERLLAGGAPGIHFITLNRSTATRQVFRNLT
AAVVS
>A0A2E9K898|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPNSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVQAAPHLTCVDASRDELKQIAQEYWDSGIRRIVALRGDLP
KGVDKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTSVYLRFRDRAAAAGIDLDIVPGILPVTNYQTLIKFAGFTNVHVPGWLHKMYEGL
DDDDQATRNLIGANIAMEQVKVLAKEGVKHFHFYTLNRCELSYAICHMLGVRAG
>A0A428JTH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter metallilatus|TrEMBL
MKVTEHLTRAEGKTLFSFEVLPPKKGENIQNLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFVPEPDGHAYACDLIGQVADLNKGAYLDEEQDDVWATNFCIGTAGY
PEKHFESPNSGADIRYLKHKVDRGAEYIVTQMFFDNEQFFQFEQKCRTAGITVPIIPGLK
PLTTKAQLTALPRSFYLNLPDELVDAVHLAPDNAAAREIGIEWCINQSKELMAHGVPVLH
YYSMGKSESIRRVAAALF
>A0A0Q7TT75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudolabrys sp. Root1462|TrEMBL
MISALRPSRFMPPGHNRIDVSFEFFPPKDEAMEKTLWESITRLAPLAPQFVSVTYGAGGS
TRERTHATVKRILAETALTPAAHLTCVAATREEIDSIVRNYHDAGVRHIVALRGDPISGA
GDKYTPHPGGYENAADLVAGIKRIAPDIEVSVSAYPERHPDSPTVEADIDMLKRKVDAGA
TRAMTQFFFENDLYFRYLDRVRARGIDIPIVPGILPVQNFGAARNFATRAGATVPAWLAE
RFAGLDHDPATRKLIAAAVAAEQAIDLLDRGVTTFHFYTMNRADLVYAICHLLGLRPQVQ
QAA
>A0A328AJ28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium soli|TrEMBL
MTPVDTALGPVARAGVGGTPRPNVSFEFSPPKTPEAEASLWEAIRRLEPLNPSFVSVTYG
AGGSTRDRTHRTVLRMVNETTLKPAAHLTCVEASREEVDEVIRDYWAAGIRHIVALRGDP
PGQIGGRYTPRADGYNNATELTAAIRRIAPFEVSVGLYPQVHPESSGVDHDIDVLKAKVD
AGATRAITQFFFDLDAFLRFMDRVRKAGVTIPISPGIMPVTNYNGLKKMAGPIGIQLPQW
LANLFEGLEKDPETRRLIAASVASETCARLAEEGFSDFHFYTLNRADLTYAICRVLGVRE
APTPDSSQTKPDRGSGGPKEAAA
>A0A2N3AD82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-1|TrEMBL
MNKLLKVNEHIAASEKTLFSFELLPPLKGQNIENIQHTIEPLMEFDPAFVNVTYHQEEFA
YKTLPNGLLEKKTIRKRPGTVGIAAAVMYQYGLNVVPHIICGGFTREETENALIDLHFLG
IKNLLVIRGDAQPSMKQFQAESGGHSHSEELVKQISDLNKGIYLEEDLLNSTPTDFSIGV
AGYPEKHIEAPNMEADLHFLKKKIEAGAEYIVTQMFFDNTRFFNFVDRCRAAGINVPIIP
GIKPISALGQLNTLPQTFNIDLPDALVKEVLKCKDNQQVRQVGVEWSITQCHELISRKTP
VIHFYTMGRADNIVKIAKAVF
>A0A1H1P1E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Z003-0.4C(8344-21)|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVERLQAQGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A3DHS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372)|TrEMBL
MLKQKILNRESGIITYGITPPKKNNTEEKIKEISQKHIERISGLDIDGLVIYDLQDEKER
VSEERPFPFIETIDPQIYSENYLKDLKIPKIIYRCVGKYTPDEFRRLTRPVSGQDAFSVF
VGAASRNQSVLLKLSDAYKIRQDVNPDLLLGGVAIPERHMKNTDEHLRIIDKINKGCKYF
ITQAVYNVEAAKDFLSDYYYYSKNNNLKMVPIIFTLTPCGSTKTLEFMKWLGISIPRWLE
NDLMNCEDILNKSVSLSKSIFNELMEFCLEKGIPIGCNIESVSVRKVEIEASIALAKDIK
YIMKGI
>A0A6P4JJH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila bipectinata|TrEMBL
MHWIPVPTVTSDFPRSKYQPTVTFTEEQTASGRDQEEQRIGPLVANKTAQRQFFYGIEIL
ATSASGKPIALDFNNFLPVLPSFVSVVWLGRRYWNVEPVKQVESLQLAEILAPRIPVLPH
ISAYRLTKKRLDDFLNLNFKSCLAVRGDLVHPGQDFPITQPIVELSHYKKGKNFSICVAG
YPEGYTSLGGGPQDGRKNIQHLKEKVEAGADCIFTQLCYQPEPIVRFIKACREAGIKVPI
VVGLMVHESIRTYDAIQDMSGVHMPEDLREELEELRMNRGGSPDSDAISKFFIKLTVNIV
GHILEADIGIWGFQFYTMNSFPPVYAALREFQKMGFF
>A0A8C9P4L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spermophilus dauricus|TrEMBL
MKHKARVLPARLRCRSLEMWASEAGSMRWSVPPSIRRLQEKMRRRMESGDKWFSLEFFPP
RTAEGAANLIARFDQMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETVLH
MTCCRQRREEITGHLHKAKQLGLKNILALRGDPIGDQWETEEGGFSYAADLVKHIRSEFG
DYFDICVAGYPKGHPDAESFEDDLKHLKEKVSAGADFIITQLFFEADTFFHFVKACAATG
ITCPILPGIFPIQGYSSLRQLMKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCR
ELLASGLVPGLHFYTLNREVATTEVLKRLGLWTEDPRRPLPWAISAHPKRREEDVRPIFW
ASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELRDYYLFYLKSKSPREELLKMWGEELCS
EESVFEVFAHYLSGEPNRHGHKVTCLPWNDEPLAAETSLMREELLRVNQRGVLTINSQPN
INGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVHYHIVDVKGEN
VTNAPELRPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYDEESPSRM
IIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPAQ
>A0A7W9C3C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas aurantiaca|TrEMBL
MTGSSTNLAEARALLLSPLGPVARAGSNRETVRVSFEFFPPKTDEAEVNLWKAIRRLEPL
NPAFVSVTYGAGGSTRERTHRTVQRIIAETALRPAAHLTCVDASRDEVDEVIASYKAVGV
DHIVALRGDPPGGGGIGGVYQPRADGYANATELTAAISRIGGFDVTVGAYPEKHPESPSI
DHDIEVLKAKVDAGATRAISQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLQR
MSGACGTSIPDWLQAHFDGLDDDPETRKLLAASVAAETCARLHEEGFSDFHFYTLNRADL
VYAICRVLGVRETMAVA
>A0A7J6X7M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalictrum thalictroides|TrEMBL
MKVIEKIREAEAENRTVFSFEFFPPKTDDGVDNLFDRMDRMVQHNPSFCDITWGAGGTTA
DLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQDK
FVQIEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPEVIDSSGIASLEAYQSDLVYLK
KKVDAGADLIVTQLFYDTDIFLKFVNDCRQMGITCPIVPGIMPIGNYKGFMRMIGFCKTR
IPAELTAALEPIKDNEEAVRKFGIDFGTEMCKKILAHGIKQLHLYTLNMDKSALAILQNL
GLIDDTKISRTLPWRRPTNIYRVKEDVRPIFWANRPKSYLTRTVGWDQYPHGRWSDSGNP
SYGALTDYQFMRPRSRDKKLQEEWAVPLKSVEDIHERFAQYCLGKLKSNPWSELDGLQPE
TKIINEQLENINLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQKAYLEFFCSQDQLT
ALLAKCKNFPSLTYLAVDKKGNSVSNVAPTDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFEIWTKVWARMYPEDDSSRPLLEKIQSSYYLVSLVDNDYVNGDLFAAFKEL
>A0A1T5F8P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis flava|TrEMBL
MTSILNSAAEARRAAASPLFADLAGDISVSFEFFPPKTEKMEAQLWDSFHTLEPLNPSFV
SVTYGAGGSTRERTHATVARIAAESRVPPAAHLTCVEASREEIDAVARAYWEAGVRHIVA
LRGDVPGGEPYRAHPQGYANAAELVAGLKAIAPFDISVAAYPEVHPDAECPQADLDNLKR
KLDAGATRAITQFFFSPDAFLRFRDAAAAARIDAPIIPGILPVSNVSQTRRMADMCGAAI
PPWMVSLFDGLDGLPAARQLIAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPAALPIKEETA
>A0A1D9P3C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio hungatei|TrEMBL
MKIIDILNSKDVTLSFEVFPPKTDAGYAAVEKAAAEIAALKPDFMSVTYGAGGGTSQNTA
NIAADLQNKYGVDVIAHLTCVSSTKEYVDSMIDAYKEKRIENIMALRGDIPKEGRVCYDY
DHAYQLIYDIKSKYSDCCIGGACYPEGHVECARQSEDIVHLKEKVDAGCDFLTTQMFFDN
STLYQFLYRIREKGIEVPVLPGIMPITNVKQVSRSVALSGSTIPQKMKIMVDRFADDPDK
LREAGIIYASDQIIDLISNGVSHIHVYSMNKPEIAAGIMRNLATIIK
>A0A4D6Y207|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buchnera aphidicola|TrEMBL
MSFLKNKYHQDIIDQKLNSLNRLVQCSFEFFPPKNIHLEDKLFSSVMKLNELRPFFFSVT
YGANSGEREKTYKIVKQIHEKTSVTTAPHLTCVDSTPNELKKLAKYYWNNGIRSIFALRG
DSNNKNHLHKMHAYDLVVLLKKIADFDISVAAYPEIHPEAKDAQSDILNLKKKVDAGANR
AITQFFFNTESYLRFRDSCIKYNINVEIIPGILPIYNFEQLKRFANMTNVSIPYWMFEIF
DGLTNDLVTQKIIGASITIDIVNILFKEGVKNFHFYTLNQAEVIYSICRLFGL
>A0A4U9HX22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia rubidaea|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSSLKPKFLSVTY
GANSGERDRTHGVIKGIKDRTGLEAAPHLTCIDASREQLSEIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITSSSLTWKATCVFATAASPPALTLKSCRAFCRCPTSSSCSASPP
>H2FYA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanimonas sp. (strain GK1 / IBRC-M 10197)|TrEMBL
MGFHSARHVEALNQSLSELNGDINVSFEFFPPNSEQMEQTLWHSIERLKTLAPKFVSVTY
GANSGTRDRTHKVIKDIQDKTGLIAAPHLTCIDASRDELRGIARDYWNNGIRQIVALRGD
LPQGMEKPDMYAADLVGLLKEEADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTIGIDVEIVPGILPVSNYQTLLKFAGFSNVKIPSWMHQRFA
GLEDDQNTRNLVGASIAMDQVRVLSREGVKDFHFYTLNRSELTYAICHSLGVRPPVAAAE
>A0A0A0UI29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum GT15|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A430RPV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus|TrEMBL
MKIRDLLKARKGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRERS
VLWAKRILGLKLNALAHLTVAGQSRKEVAEVLDRFVEAGVENILALRGDPPQGERAFRPH
PEGFRYASELVAHIRTRYGEGLSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRMGIEIPILPGIMPITSYTQLRRFTEVCGASIPGPLLSKLERHQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGFKPQP
>A0A5B2TN36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter flavus|TrEMBL
MKVTEHIKQAKGKTLFSFELIPPVKGKSIQELYDNIDPLMEFQPPFIDVTTSREEYVYID
KGGLLEKKVTRMRPGTVGICSSIQHKYHVDTVPHLLCGGFTKEETEYVLVDCHYLGIDNV
MALRGDSMKEERYFTPTEGGHCYAKELVSQIRNLSRGEYLHETIDSDDNANFCIGVAGYP
EKHLEAPSLQSDLKRLKEKVDAGADYVVTQMFFDNQKFFEFVEAAKNIGITVPIIPGIKP
IAVKRHLQLLPQVFRIDIPQDLIDAVEACQNNKDVRQVGIEWAIQQSKELKSAGVPVLHY
YSMGKSDNIKAIAKEVF
>A0A2T7TJN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Bz4|TrEMBL
MWRARDFAKPSYRRLLETARYEILPTAAIADEVMANLPVGRRLTITASAGKGLAATLAVT
ETLSRAGYQTIPHVAARMVQGRQHLEEIIEQLVAAGVDSVFIPAGDARPDKDSYAGSLEL
LRDLTALGRPFRSVGVAGYPESHPVIADDVTIQAMWDKRNHATNVVSNLCLDPAVIAAWI
ERVRKRGVLMPLWIGMPGPVERSKLLSVATRIGVGESTRFLAKNTSLFARLAAPGGYSPE
RFLDRLAPALVKPESRVEGLHIYTFNQVRQAEEWRRNLIGRLGGSVS
>A0A515KPW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tardiphaga sp. vice352|TrEMBL
MSDIAAPEPTRLPNISFEFFPPKTEEMERSLWETITRLAPLSPKFVSVTYGAGGSTRERT
HSTITRILNETALVPAAHLTCVNASKGDIDDVVAQYHDVGVRHIVALRGDPTTGIGTPYL
AHPDGYQTSADLVASIKRRYPDIDVTVSAYPEKHPESPDFDADIDVLKAKVDAGATRAIT
QVFFDNDLYFRYLDRVRARGIDIPILPGIMPMHNFKQARSFVTRAGTSVPAWLDEKFDGL
DNDAETRKLVAATVAAGQVQKLAKQGVSDFHFYTMNRADLVFAISHLLGFRPNGAQKAA
>A0A0T9ZWS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIELIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A1Q9JPF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. 499|TrEMBL
MKVENLFREKRPVISFEIFPPKRDTELKNIDGTLEILSRLNPDFISVTFGAGGSATNNKT
IALAKKIKQEYGITPIVHLTCLNYSKNEMDELLAELKENEIENVLALRGDRNPDIEPKKE
FHYATDLVKYIKAHGDFDVCGACYPEGHTEAESIVADIQHLKEKVDAGATHLISQLFFDN
NIFYSFQEKTKLAGINVPIEAGIMPVINKAQIERMVTLCGASLPEKFQCMMNKYENDKDA
LFDAGIAYAVNQIVDLLAHDVDGIHIYTMNNTKVAERICKGIENLI
>A0A660RSU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfobacteria bacterium|TrEMBL
MIAGSNLEQVLSSGQFAVTGELGPPKNGNYEIVRDKARILKGHVDAVNITDCQTAIVRMS
SLTAGLVALAEGVEPVMQMTCRDRNRIGMQSDILGASALGIKNLLCLTGDHQKFGNHPQA
KGVFDMDSMQLLCMARGMRDDKIFQCGEEIKDHEPRLFLGAAANPFADPFEYRPIRLAKK
VDAGANFIQTQIVYNVDKFARFMEMVRDLGLHERVYILAGVTPPKSVGMARYMKNFVPGL
DVTDEVIERLKDAKDPKEEGINICVDIIKQVSEIPGVAGVHVMAIEWEQAVPEIVSLAGL
SPRPETKMVESRLMSSDSIELIVSRVRKESKAEIEKALEQAKAEVRASRDLVVKEKDRTA
SEISGLKKQAEEARAIAEQKDTEIERLTAELAEIKAGPGPGR
>A0A6L5YMI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia porci|TrEMBL
MKVSDILKKDTVTISCELFPPKQGTQLENYKKIVAEMAALKPAYISCTYGATGGTSDYTV
EIADAINANHIPAIAHLTCASSTKEKVRSVITELKERKIENILALRGDIPEQADFPLPDQ
YHHAYELIEEIKSMGDFCIGGACYPEGHPEAATMDEDLDHLKEKVDAGCDYLTTQMFFDN
SIYYNFMYKALKKGIQVPVVAGIMPVTNASQVKRIISLSGNLVPAKFTNIVDRFGNDPQA
MKQAGIAYATEQIIDLIANGANHVHIYSMNKPDVAGAIMDNLSHIYVRD
>A0A7K9PDQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pachycephala philippinensis|TrEMBL
MVNETPHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPR
>A0A2P7V1X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus fortis|TrEMBL
MTTSKKDLRAYLKDHLLVGDGAMATQLHGLGVPVGVSFEELCLSNPRLVHDVHTSYYQAG
ARFLETNTYSANRDALSRYGLEHKVARINRLAVAIAREAAQDDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGVDGLILETFLDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYALTDAFSELKAAGADVIGLNCRLGPAELLRSFENTVIPEDALLSVFPNAGRLG
MTDGEYAFKSSPEYFGQSALRLREQGVRLIGGCCGTTPAHVKAIADALESLEPQARVNPT
NVAGDRPSISVQNTREREKPSIVERVKTATTIIVEFDPPRDLDADQFLHGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKGRHGIDPLLHIACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMDAAVARLEKKVEAGADYIMTQPVYDAESIRNVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSAEALERMKKVQGEAARQEGIAIAKELVDTAVSYFNGIYLITPFNYYE
MAADLIQYTRQQSSLVKQAQP
>A0A0Z8IXX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLRAA
GLAYTVDQIVDLVTNDVAGVHLYTMNNAETARTIHQATHSLFKHYS
>A0A7X1KMJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium flavum|TrEMBL
MEGYSLEVTSKDIPALTEATGKIWRECPIAVPYLPGETYEARIAAAKSVRELGFEPMPHF
SARRIESREEFETYLEGVVREAGVERCFVVAGDPSTPAGPFSDSSSLIETGAFERAGIKV
IGVGGHPEGHPVMSKAECWDILKSKCEDIEARGMAPLIVAQFAFDADAMLAWLKELRERG
LDYPVRVGVPGPAGIKTLARFAAVCGVSASASVLAKYGISLGRLIGTAGPDKFVDKLVAG
LGPEHGRIRLHFYPFGGVSKTVEWIENYQQTKG
>E7RFH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus donghaensis MPA1U2|TrEMBL
MGLLDELKTRILTADGAMGTLLYSYGIEYCNEELNLQRPEIVEKIHLDYIKAGADIIQTN
TYGANALKLARYGLESQVAEINKAAIDIANRAAAPGGQFVFGTIGGIRGIRKSDASLQEI
IAMVDQQATHLLEGNPDGLLLETYYDFEELAATVKHLKSITNTPLIAQVSMHDPGILQNG
MSLNDALHQLETLGADIVGVNCRLGPHHTIQAFEEVTLPEKAFLSAYPNASLLDVEDGRI
VYESEADYFGRAALLLREEGVRLIGGCCGTTPKHIEAVKKHLGQLAPIVRKEVTERKPIV
IREAEALEVKPLHEKAKTERTIIVELDTPRHLDVTKFLEGSVALKAAGVDAVTMADNSLA
SPRISNMAMGSILKHTEDIRALAHITCRDRNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKKLNEGISFSGKSLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIESGADYFISQPVYTKEKITEIYEATKHLETPIFIGVMPLTSIRSAEFLHNEVPGI
KLSDDALARMRACGDDKDRATEEGIQIAKELIDTAAELFHGIYLITPFVRYDMTVELIHY
IRQLDQQKESDRNHVQASY
>A0A2J7QG60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptotermes secundus|TrEMBL
MRETVLQLLDNEKYLWSSRKSLVTRNSLQNLYNCSPLFTAITWHIKTSAMPVPPVLPFGK
LRALRLGAEISNINSVLLHLSSVGLTKKQVCQVLWYIRDMGIRNIFALRGDRPERNNDLK
LDRGFPYASDLVSFIQERFGDYFTICVAGYPLGHPEAVSFEQDLAHLKEKVDKGASFIIT
QFFFKAGDFVNFVQWCRRIGITVPIIPGILLIQDYTSLIHISSACSVEVPRSVLDIIEPI
KDNREAVRKFGVHLAVEMVSYLFSQNYSNAAHFFTLNRQLSVIETCKCLGFCLLEPARPL
MHHERCKKSKRIVKLL
>A0A4S5ETN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Frankia alpina|TrEMBL
MTAVRGLSAKPATMGEFLASGRLSFSFEFFPPRTPEGECHLWTALRRIEALRPSFVSVTY
GAGGSTREGTIRVTERVATDTTLTPIAHLTAVNHSVAELRQVIGNYAGAGVRNVVALRGD
PPGDPQGTWTAHPQGLGHADELVRLVKSVGDFCVGVAAFPDKHPRSPDFDTDAQYLVRKF
DAGADYAITQFFFGADDYFRLVDRVRALGCDKPIIPGIMPVTNVAQIVRMAQLSGADFPP
VLAARLQAVADDPAAVRAVGLEVATELSRRLLDGGAPGLHFITLNRSSVTREIFEAIR
>A0A0T7ZSR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSYFITQPVYSKEKIKEVYEATKHLDIPLFIGIMPIASYNNSLFLHNEVPGIKMSEDVLN
QFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYLITPFQRIDYSLELAAYSKAITQNK
EAIS
>A0A4T2GK37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MTGQAPSLSFEIFPPKPEVGNEKILQALREMQGLAPHFISVTCSNNNLNVEETTVRLSDY
VRNDLQVPTIAHLPAAYLTKEKVSSVLQSLDRIGVQRILALRGDIIQGLPPKKDFRYATD
LISFIKEEAPHFDIIGACYPEGHPESGSAVADIKNLKKKVDAGCSSLVTQLFFDNDVFYD
FQEKCYLADIEVPIIAGIMPIINRNQALRLLKTCENIRLPRKFKAILEKYEHQPESLRAA
GLAYAIDQIVDLVTNDVAGVHLYTMNKAETARHIHQATHSLFRHFS
>A0A4S4FFD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudolongum|TrEMBL
MTIFSLEVFPPKRTAPVGTIYDTLDGLTGLSPHFISVTYGTGKSADRTATARIAHTVRAE
YGIPAVAHLTAQYLTEDSAEEALAMFDEAKVAGVLALRGDRNPDREPAGVFHYANELTAF
IRERRPDMKIYGACYPEKHPQADTLDHDIDNLKRKVDAGVTHLISQLFYDNSDFLRFLDK
ARAAGITVPIEAGIMPPVNARSVRHMAGMCSSKIPERLATLLDRWQDDPNTLKTAGILYA
SEQINDLLARGVDGIHLYTMNHPCVTRRIWANVQDLFA
>A0A420IVM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Golovinomyces cichoracearum|TrEMBL
MFISDKLAEAERSGQPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGNIA
QLTVEMVSIAQSHYGLETCMHLTCTDMGKEKVDDALSGAYKSGCTNILALRGDPPRQMEK
WTRTEGGFLYAKDLVKYIREKYGNHFDIGVAGYPEGCDDQDDPELLLDHLKEKVDAGGTF
IVTQMFYDVENFLEWVSKVRAKGISVPIIPGIMPINTYASFIRRANHMGCKIPPKWATAI
ESVKNDDSAVRSIGTGLVAEMCRKILASGLIHHLHFYTMNLAQATRMVLEELNLTPSEGR
PLKTPLPWRQSLSPRRRDEDVRPIFWKNRNRSYVMRTQDWDEFPNGRWGDARSPAFGELD
AYGIGLKGSNEKNRKLWGEPKCVKDVANIFVKYLEATIDSFPWSETPITSESDMIKNELI
DLNQRGLLTINSQPAVNGVKSSDPVFGWGPTNGYVYQKAYLELLVPDYLIDEILERVSRD
TDLTYHAVNIDGNLKTNTPNDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEAYRLGLD
WAHCHSALSPSRQLIENMMKKWYLVNIVNNDFHKTYGIYKVFEGLMVKDLEKPYSACISN
DESIPRTNGHKVKDPLTNGHMSKDPLMNGLGTNKPTTNGHKISAA
>A0A5N4WMU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter tandoii|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSNDHFHIEVAAYPEMHPQAESFDLDIQRFCDKANAGANAGLTQFFFNPDAYFYFV
DRIQKEGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTVSIKAFGHE
VVVKLCERLIAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A6Q2Z9J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Esox lucius|TrEMBL
MVNQVQTVDDTWRRCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIAST
AVNYCGLESVLHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPIGTDWEEEEGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAQSYDEDLKHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKENDAAIR
NYGIEHAVGMCRMLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEKSVYEVFTSYIMAEPNQAGHKVMCLPWNDEPLAPETNLLKDELAKVN
RRGVLTINSQPSINGKPSSDSIVGWGPPGGYVFQKAYLEFFTSSENVTALLQVLKKYEPR
VNYHIVNVQVDFLEYVFSLHGSIN
>J7IPP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus meridiei (strain ATCC BAA-275 / DSM 13257 / KCTC 12902 / NCIMB 13706 / S10)|TrEMBL
MENKFKESLLDKNTLSVTWELVPGRGANEKAQQTAIASAEQAAKGGRVHALTITDNPGGN
PAILADYLGMEIIKLGIEPLVHFTCKDKNRNQMESQLYALDRAKVRNLLVMTGDYTYSGF
KGRPKPVFDLDPSNTLQLITEMNKGLEVPGMKGPTYHAPSDFFAGAAVSPFKSTEAELMI
QYYKMKKKIQGGAQFIVTQLGYDARKCHEVLQFLKVNNLDVPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNTEKTAEDKGVGQRMLRAAKMYAFMKGMGFAGVHIGGHNLKYEQ
VEYIIDKGEELSPNWQDYIKEFDYPQNNGFYYFEKDEKTGLNTDRPTNRANRPLDAPAGA
MNSMMRGMHSLMFTPNKKLFPVLRSMYHAAEGKKKAEKRLHAVEHIAKVVMLDCKDCGDC
AILDIGYLCPMSQCPKNQRNGACGGSLDGWCEVFPKEKKCVWVRAYARLKKYGEEATLDV
PPVPPANWDLYQTSSWSNFYLGKDHSAPILGIKRPESKIKK
>A0A8G1EEI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter sp. N10|TrEMBL
MALKRISYEFFPPQSLDASFRLWETVQALAPMRPDFVSVTYGAGGTTRKLTHEAVATIRR
NYGLNVAAHLTCVGASKAETLAIADSYAAAGVTEIVALRGDPPKEAGRFVPHAEGFANSV
ELVEALSPRFKVRVGAYPERHPEAADARADVRWLKRKLEAGAVSAITQFFFEAETFLRFR
DLCAKEGITAPIVPGILPIQSWEGVKRFALRCGTSVPGRLDEGFQIAARDGREELLALTQ
CTTLCDRLISEGVEDLHFYTLNRPHLTREVCRALGVAPEVALEKVA
>A0A6I7HUZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciceribacter lividus|TrEMBL
MSPDINPIDPGLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPHDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRTMRDEAKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPHRLAKKIAAGAQFVQSQYCYDVPMLKTYMQKVRDLGLDEKCFILVGVG
PLASARTAKWIRSNVPGVHIPDAVIARLEGAQDQKKEGKQLCIDIINEVKEVAGVSGIHV
MAYRQEEYVAEIVHESGVLKGRRPWKREPNPVDALVAERLEAIREEKVEDQQQLAGIAAQ
HPH
>A0A1H1L6S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmoricola scoriae|TrEMBL
MPGTPVRIGDLLASGDRSFSFEFFPPKDAAGEEVLWRSISELEPLRPTFVSVTYGAGGTT
RDRTLAITGRIARETTLLPMAHLTCIGHTTTELERILGSLEDAGVRNVLALRGDPPGGPG
TPWERTEGGVDHASDLVSLVRARSELCVGVAAFPEGHRDAASLDDDVAVLKAKQDAGAEF
AVTEMVLRASDYLGLVERARDAGVTFPIVPGIMPILGLTSMAKMVELSGRDIPAEVEARI
RPHADDPAAVRAEGIAIATELCDDLLAGGAPGLHFYTLNRSRATREIWAALSLSA
>A0A369VE96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces parvulus|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPTADWIAHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFQAESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PPELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A2E6EAD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseia sp|TrEMBL
MLKTFRQAIRNSDFAVSAEIYLRPETDAASLRAQADTLKDSVDGILLTDNQYGQLHLSTT
AAAAILLDHGTDPIVQLTSRNRNRIALVSDLLGAATVGVTSLMLVAGERAPEQFQPRPKP
VLDVNAVDLIRIANTVNADENLTVKPDFLVGGVVTPVMPKPDWKAKQLREKVDAGAHYLQ
THICMDVTLLRRYLKHLVANKLIQRTSIVGAVAVLGSAEDARWLKDNRPNVMLPDRIIGR
LEKSQDPRREGILIAAETIDAMTEMPGIVGVNLMASKDLTAIPEVIAAAGIHG
>A0A173ZXM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi|TrEMBL
MKTTDIFAKKPVLSFEVFPPKRTNPVETIYETLDSLRKLNPDFISVTYGAGGSENCKATT
EIASRIKNEYGIESVAHLPCIGLKRDDVISLLGGFKRAGIDNILALRGDIPEGGRPDGDF
GHASDLISFIKENDEFKEFNVLAACYPEGHTESENILTDIRSLKTKVDAGADHLITQLFF
DNDCFYRFRERASLAGIHVPVEAGIMPVTNKKQIERMVSLCGVSLPSKFTAMMERYEHNP
EAMRDAGIAYAVDQIVDLIARGVDGIHLYTMNNPYVAAKIHEAVYRLLAA
>K9SCF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geitlerinema sp. PCC 7407|TrEMBL
MLNRLRSAVNAGEFLVTAEITPPKGGNPQRMLEMARLLKGRVHAVNITDGSRAVLRMTPL
AASALLVQEGIEPVCQFACRDRNRIALQADLMGAHALGIRNVLALTGDPLKAGDHPDAKG
VFDLESVRLLTLIRKLNQGSDWNGKALTDEPTDLFAGAAVDPQCPSWSGLQRRFERKLEA
GAEFFQSQLISDFDRLGMFMDKLGNAGGKPILAGIFLLKSAKNAQFINRNVPGVQIPQHL
IDRLANADDQLQEGIRIAAEQVQLAKELCQGVHLMAVRREDLIPQILDLAGVTALQPPVL
NSVR
>B2A780|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF)|TrEMBL
MKISEIFSQSNGPVVSFEIFPPKRKKNQSKEDFDSLLKTIDNLARLKPDFISVTYGAGGT
NSDGSLEISEYVKNKGITSLPHFTSIGYPVEEINSYLGTIYNKGFENILALRGDLPKSPS
KADLVWRDFLHATDLIKVISRDFPNFCIGGAAYPEGHQESSYAGQDIEIMKIKEKMGVKF
FLTQLFFNNDNFFKFMENVRNNGVESPVSAGVMPLISPKYVDKIIELSGVKLPKELENAL
ENYRDDEVEFRKRSLDYCVRQVNDLFERGVDGVHLYTMNRHEAVEEILDQVDSNVNREVE
LSKQT
>A0A356JQM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaeria bacterium|TrEMBL
MLYFIYLITKKQPNWNDTMNCLQRKLAESLVIFDGAIGTEIYRRNFFVNASFEQLSVTNP
DVILDIHRQYLDAGAEVLTTNTFNANARRLGKFGLADQTATINRASAELARQAVREAGLE
GSVLVAGSVGPIGEPESAADTRSRDSILVEQLEALAPVVDFIIFESLRTTIDLAAALEAV
KAFPELVYVLSFAVDRHAENHSGDGISEFGRLISTFPGQRPTAIGLNCGGGPESTLGELE
ILVKRTKLPVIVQPNAGQPRGVDGRMIYMTSAEYFSTYAKRYAMLGAAAIGGCCGITPAH
IRELARTIKPLMRAEKQELPKVEIVECDLKEPVPLAEKSSLGAKLAAGKFVTSVEITPPR
GFDLASTVAGARKCKEAGIDAVNLPDGPRASARISPFAAAVAIQQQVGIETVLHCCCRDK
SVIGLQADLLGCAGMGINNILFITGDPPKLGDYPFSSGVFDVDSIGLVKIQSRMNRGIDL
GGKSISAPTRAVIGVGADPSAIDLEREYRRTCEKVEAGAEFIITQPVFAIETLFAFLDRI
AHLKTPLIAGIWPLVSYRNAEFMKTEVPGVVVPDAVMKRMAAAGTKEEQREAGLEIARES
IAAIRDRVQGIQVSAPFGNVDLALRVLK
>A0A7X8MKH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MKVIDLYRKGAPVLSLEIFPPRKDYPVETVFTTIEKLTRLQPGFIGVTYGAGGSNRDRTV
EIAARIKRDYQVEALAHLTCVRHTRQEIAEILDELQREGIHNIMALRGDIPEDEDDFQLE
KQEYRYAYQLINDVRQRADFGILAAAHPEGHPECRRLHEDLDNLKRKVDCGVDLLVTQLF
FDNRIYCDFVDRAITKGIDCPIVPGIMPVLNVKQIKRMVYLCGASIPPKMLSLLDRYENN
PADMEKAGIEYASEQVRDLLEDHVDGVHLYTMNKPEQITQIVDNVGLR
>A0A2R6CT49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QH_2_65_14|TrEMBL
MPFESIEEQVAHLPDYATITITASPTLGLEDTIVWTENLAAEGYTIVPHIAARYVRDADH
LDEIAGRVADAGVTSIFVPGGDREEPVGEFESAYQLLTALEELGYDFEEVGITGYPEGHA
FLDEETLAESMQRKAPYATYITTQICYDPDRILEWIGTVRDERGIDLPVEIGIPGVMKYQ
RLIGISRKVGVGESVQFLQKTTGILDFVREVIGSRGRYEPDDLVDGLTPYADDPHYNIRR
LHIYTFNQVSDTEAWRTARLNR
>A0A7X6UK81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MKIIELYKSKRPVLSLEIFPPKNNFPLESIFTTLDKLIELKPEYISVTYGAAGSTRERTV
EIAARIKKEYGIEPQAHLTCVNHNRGEIQGILAELKREGIQNIMALRGDIPDQAVDFDFS
TQDYQYAYQLIQQIRQSDDFGIAAAAHPEGHPDCRRLSEDITYLKQKVDAGVDFLITQLF
FDNRIFYDFCEKAEKSGIKCPVIPGIMPILNANQIKHIISMCGASIPAKLLNIVNKYEKN
QADMEKAGIEYASQQIEDLRDSKVVGIHLYTMNKAEQITQIVKNCNL
>A0A7C9NNH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldimicrobium sp|TrEMBL
MEPKSHLHKVLSSGQFAVTAEIGPPRNADPEVIRKKARLLKGYVDAVNITDCQTAIVRVS
SIASAVLVMSEGLEPVAQMTCRDRNRIGIQADLLGASALGIRNLLCLTGDHPKFGNHPMA
KPVFDLDSIQLLKLVSDLEEGRFANGEEINGKKPVFFRGAAENPFAEPYDFRAYRLAKKI
KAGAQFIQTQIIYNVERFRKFMEECERLGLLDKVYILAGITPPKSLGMAKYMKHHVPGLE
VPDEIIKRLESAKDVREEGINIAVEIIERVREIPGVRGVHIMAIEWEEAVPEIVKRAGLY
PRPAYEDISYPFVVEKVVEKVVEKVVEKPVEVVVEKVVEKPVEVIVEKVIEKPVYMSIDE
AISELEEGMARGEIPFETLVEILASLKAGLKQIRSGIESVEETMRLLEEEFIKKPKGSPA
TPITKKEEIKKEEPKPAKFLEEKVIEVSAPSVEVKEEKPEVEPKVEVKPEVKPEVKVEEK
VEAKPEVPPEEKPEVKPVEKPEEKHEIKPEVKVEEEKPAPKVEAKAEGRAEVKVGGFKGV
YRPISERAKLVPPDSYLEKATGEIKEVVIGRNGKSIKVGGAKGLNFHYFEGEFKNPVRIA
FEVLDVKPEDWPESLAKYYSDVWHDPALWAKKCVEEYSAETVCIYLQGTDPNGLNLPASH
AVEVVKKVKEAIDVPLIVWGSGNAEKDVEVLREVAEVVGDRGAVIGPVVEANYRTLGATA
MGYGLPVIASSPIDVNLAKQLNILLENIGVSLDKILMDPSIGALGYGIEYTYSVMERIRL
AALFGQDTKLACPFICSIGKEVWKTKEASMPTDEVFGEQEERGVLMEAITGVALAIAGGD
LLIMRHPLAVKLCYTLFNALSEGLQSSV
>A0A7C2P5F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldimicrobium sp|TrEMBL
MEPKSHLHKVLSSGQFAVTAEIGPPRNADPEVIRKKAKLLKGYVDAVNITDCQTAIVRVS
SIASAVLVMSEGLEPVAQMTCRDRNRIAIQADLLGASALGIRNLLCLTGDHPKFGNHPMA
KPVFDLDSIQLLKLVSDLEEGRFANGEELKGKKPVFFRGAAENPFAEPYDFRAYRLAKKI
KAGAQFIQTQIIYNVERFRKFMEECERLGLLDKVYILAGITPPKSLGMAKYMKHHVPGLE
VPDEIIKRLESAKDVREEAINIAVEIIERVREIPGVRGVHIMAIEWEEAVPEIVKRAGLY
PRPAYEDISYPFVVEKVVEKVVEKPVEVVVEKVVEKPVEVIVEKVIEKPVYMSIDEAIFE
LEEGMARGEIPFETLVEILASLKAGLKQIRSGMESVEETMRLLEEEFIKKPKVSPATPIT
KKEEIKKEEPKPAKVPEEKAIEVSAPSVEVKAEKSEEKPEGKPEVEPKVEVKPEVKPEVK
PEVKVEEKVEAKAEVQPEEKPEVKPEVKPEVKVEEEKLAPKVEAKAEERAEVKVGGFKGV
YRPISERAKLVPPDSYLEKATGEVREVGIGRNGKSIKVGGAKGLNFHYFEGEFKNPVRIA
FEILDVKPEDWPESLAKYYSDVWHDPALWAKKCVEEYSAEAICIYLQGTDPNGLNLPASH
AVEVVKKVKEAIDVPLIVWGSGNAEKDVEVLREVAEVVSDRGAVIGPVVEANHRTLGATA
MGYGLPVIASSPIDVNLAKQLNILLENIGVSLDKILMDPSIGALGYGIEYTYSVMERIRL
AALFGQDTKLACPFICSIGKEVWKTKEASMPTDEVFGEQEERGVLMEAITGVALAIAGGD
LLIMRHPLAVKLCYTLFNALSGGLQSLA
>A0A842BYJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria innocua|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPDIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDKAYLAVYPNASLPEVQE
GKVIYQSDTDYFEHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLESTKPVLEKEVRPIL
ELVPEEVEDEESGERLLDKVKERLTILVELDPPRTFDTSKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEQGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYVQNKQQLQIASK
>A0A7X7NXZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MKIIDLYRRGGVVLSLEVFPPKIDYPLETIFQTISELTKLQPGFISVTYGAGGSSRVRTV
EIASRIKK
>A0A1B2AGV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tsuneonella dongtanensis|TrEMBL
MNAEIALGEPLYASLPGDVGVSFEFFPPKTEKMAETLWSSVQTLAPLGPDFVSVTYGAGG
STRERTHAAVERIIRETGIPAAAHLTCVDATRDEIDAIARDYWDIGVRHIVALRGDVAEP
GAAYAPHPQGYANAAELVAGLRKIAPFEISVGAYPEKHPDSADEAADLENLKRKIDAGAT
RAITQFFFEPDCFFRFRDKAAAAGIDAEIVPGIMPVMSFASVQRMSGLCGTAIPGWMETL
FEGLDDRPAARQLVSATVAAELCRRLYAGDVRHFHFYTLNRAELSYAICHLLGLRPKDPS
>A0A5C8BUB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseriales bacterium|TrEMBL
MRVIEHLNQAQKPLFSYEIVPPLRGSTTSINEIFNIIEQLLPYDPKWINVTTHASSLLYV
EKSDGSITRRIHKKRPGTLGICGVIQNKYGIDAVAHVLCQGFSQQETEDALIELNYLGIE
NILALKGDNLNYNRQLDTSESVNKHAVDLVKQVAKMRQGLFLGDTEYPAIDFCTGVASYP
EKHFEAANMELNIEYLKQKIAAGAEYVITQMFFDNQKYFSYVAACRAAGITVPIIPGIKV
LKSANQINSLPRLFHVDLPHELVAELLESPQNAAIIGKEWAARQVAELLTAGVPCVHFFL
MNDVSSVLEIIKKYN
>A0A0D8XM92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyocaulus viviparus|TrEMBL
MSSDGGSVLNVHDINCSDDETISFEVGQQAKYIPLHERISRRISDKTPFFSLEFFPPKTA
NGVANFFTRLDRFNEGGPLFIDITWHLASDPANMNKETSSSSIAAGCLDYCRVDTMLHMT
CAHYSKEQTIKHLEQSKSVGLRNILALRGDLNTDLDETPIYKYRALDMIRYPSGHPEAPS
YKADLQYLKSKCDSGAQFIITQMFFEAEVFERFVRDCREIGITVPIIPGIMPIMGYDSIR
RIATLSQLTIPQSILSDLEPIKHDDDAVRKYGTIRAIEMCRRILSNGAAPAVHLYTMNRE
GACREILQELGLWHKRPMRALPWEPHGSIHPLRFVLYHFASFHCMKMVYHFCLRCKEDVR
PIFWSARPKSYIYRTRDWDDFPNGRWGNSSSPAFGDLNDYYLFHLKLSGDFYLLIAILQA
QTKKEDLLKMFGEELKSFDDVKKVFKNFISQETNENGVKVTSLPWNEKEIGMQEETKLIN
DQLLWCNENGILTVNSQPPVNGAPSTDPLVGWGKPGGYCYQKAYLECFISKDNAMSLLEI
IDDFYPRVNYHLINHDGSFDRMNGESTTPIAVTWGVFPGAEVAQPTVVDPLAFRAWKDEA
YDAWIKSWANLYPKDSYSRKIIQKIYDDFLLLNLVDNDFQKPVIIYEMLEKVLKRTEERN
ASNCTQVEL
>A0A2J0N041|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG_4_9_14_0_2_um_filter_42_8|TrEMBL
MALCDKIKSGKFIITSEIAPPKGIDVEEILKDAELVKGRVDAINVTDLQSSVMRTGSLAI
CKLLIERGLEPVFQITCRDRNRLALQSDLLSAAVFGIENVLALTGDHPALGDHPGAKPVF
DLDSMQLLEAIRDLQAGKDMAGKELKGSPKFCVGAVVNPGADPIEPEIMKMEKKIQSGAQ
FFQTQAIYEMHLFEKFLKASEHLHTTIIAGIVLLKSAGMARYMNKNVAGVFVPDNLIEEI
DKAKDKSAKSIEIAARLIKELKPMCQGVHVMPIGWDKKVPLVLDAAGL
>A0A0F9LHS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MTKRPAFSNLMKEIRAGKFVITGELEPEKDFDLSAVLHSAEEMKKTGKIIAANVTDGPQG
DAYTCSMVPSYLVQEKVGLETVWQMTVRDRNRIALFGDVVGAAILGLKNILTLSGDHSGL
GDNKKARPVFDLDSTQFIELVSKIVDKGTDLEGKEIKGGPIKG
>X0YW87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
VGANVMGVHNVLCVTGDNARIGPTPTSNTNILDFDAVQMLWILRRMRDEGIYLDGRKMKS
PPKLFLGAAASPFASEPKFQALREEKKINAGAQFFQTNLIFDPDGLDLWLEALHKRNILD
KVYILAGVTPIRSNRMAQYLYHNIPGVILPQKILHRFEEAREDDYEELGVEIALEIIDKI
KDKKGINGIHLMSVGWEAIVPRILKDAGLGITLLISD
>A0A1G3QN29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium RBG_16_49_21|TrEMBL
MGFITSLGNKFVICADIDPPKGVDTAGFFRTAHILKGRIDALIVNDMPSAVMRMGSLAAS
HLLKEKGFEIIYNLSCRDRNVLALQSDILSAAALGVENIFITRGDIITSGDHPHAKPVNE
INDDDLLTLLKKLKEGTDAGGNKLSSSPQLNIGAAIQSNQAGDALEKEIEKMKDKTNKGA
VFFLTPPVFDLNAFEVFIKKARRAVQVPIIAELIILKSVATARYINKHIDGIYVPDKYID
RLYSAPDRQKESIAITAELINGLKQLCNGVNIKAMGWEEKIPAYIDAVEG
>X1J1Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MAKSLFEEKLNSSKFLVTTEIGPPKGVDTSEIVHHIELLKDKVDAINVTDHQSSVMRFPS
LGGCLLIKEHGGEPILQMTTRDRNRLALQADLLLAYSRGIRNVLCLTGDSIDVGDHKEAK
PVFDLDSVQLIRMVR
>X1VGA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MVELARAAGLCTGVVFDPSPETQGLDKETERLKRKADKGAQFAVTQPVYTSAAAQQIAEA
TRGAGIPVMLGILPLRTPRHAEFLHERVGGISVPEN
>R8CZF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus HuA3-9|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTSIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPNFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRKRMDGHETKEAAIEEGIHISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>X1SUA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MIHHIQNKIYHVEFLPPKQDSEKLEKDLEIFSNKYLRAMKSGYCACITDNAMGLLSFQGT
EMIEELDLPVIPEQLMIHLNTFHTKDNLNNILDMCKSKGIRHLLIITGDGSERLPKLRPL
DVGATDVESVTSVELLKYINREYTDTFVLGVAFNPYEL
>X1LGD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
GNELDGKPDFCLGAVVNPGADPLELQLVKMGKKIEVGARFFQTQAVFDLEMFDEFMKKAS
QFGVPILGGDNYPEISGYGQIYE
>X1KCZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
VRNILALTGDPPEVGDYIMATGVFDVDSIGLVRMVNKLNNGYEYGGNELKDKTDFFIGIA
VNPTAQDLTKEIKRFEEKVSAGANFIQTQPIYDIGLLEKFLKLTAHINIPKIIGIMPLKN
YKMVEYLNNNLPGIFVPPEVKERMRGKDVEEGVKISRELISKIRKFKEVAGIHIFPLRDM
NLVCRLFD
>A0A6A5SDM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clathrospora elynae|TrEMBL
MEKITDKISALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRSLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDEDTPPEQDSNKEFTWAIDLVRYIRREYGDYFCIGVAVYAEGHSDQSHPEHQEPQFDL
PYLVEKTKAGADFLMTQLFYDVEAYEKFEKMLREHESGVFKSIPIIPGLMPIQSYKILLR
TTKLSHAKLPADMLARLETVKSDDELVKQVGVKIMDEMVEHIKARPDAGRRGFHFYTLNL
EKAVSHILEDTHLIPPTTTQDDDDIIVETTPAINLIPPPNGLTPRERRRSSAVNSGTRNR
VIISQPSATKSSNYSFEATDEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRW
GDARSPAFGEIDGYGPTLHVSNPQALKLWGYPTHKHDISTLFRRHIEGDLEAIPWSEQGL
SPETSTISKQLLALNAKGWWTVASQPAVNGVRSTDPVFGWGPKNGYVFQKPFVEFFIPSA
QFFALKPKLDAHDQITYFAGNARGDFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRS
WVEEAFSIWREWQRVYPPRSESSRLLGELRGDVWCVNVIWGDFVNGEGLWAFLDK
>X1PRH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSLQSLLEAGKFVVTAEVGPLKGTDVTEIKEVAELLRGRVDAVNVTDQQSSVMRLGSLAT
CHLLKEEGLDPIFQMTCRDRNRLALQSDLLSAYVLGIENVLAITGDLPSLGDHPQAKPVY
DLDSVQLLWVIERLNEGYDMAGNELKGKPNFFPGAVVNPGADTEAAFELQLIKMEKKMTV
GARFFQTQA
>A0A357ZTC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga naphthophila|TrEMBL
MRKSLEIGKCVVLEVLTPRGTNLGRFMEFTEEAWKTGIDAFTVTDMPMGRVRMAPWAASH
LLVESGKDVLMHFTRNTRNMIRIQSDLLGCHALGVKNLLLLSGDNPSHGDYPETTSVNDI
DILDLIRLTKLMNEGTDLAGNKIYGKTDFFVGGALNPFSDEDVERAKQKIEAGVDFLVTQ
PLFNSEVAKKIKEELNTKILASIVFFENAKQMSYFSNVPGIEIPDEIVNSAEKGDDYLKE
KSFESVLRFVEETKGVLDGFYIVAIVKDLEKIRKVVEIAKS
>S2YWS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HGB0020|TrEMBL
MARSADPDKSVDSVVREAGIEVIPLKGAEEKVALVPAGTTVSITCSPRFGLSRTLDHVAA
ARRSGHRVVPHLAARMVEDRRHLRDFVRTVNDLGVDELFVIGGDGEEPVGTFTEAADILR
ELGEFDHELSRIGVGCYPEGHPRISDEALFDALQRKQQYADYMVSQLCFDAHALAGWLRS
ARARGVTLPLRIGVAAPLQIRKLIELSIKIGVGQSVRFLSKQHGLVGNLLLGRSYEPLDL
LLALQQEMSFSEFTVEGLHLFSFNQVQPTLEWLSRAGGAEKAG
>I4M6R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis 00703C2mash|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIESQNAAGVFNHASDL
VSYIRSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTYLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKMSEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A3E1KCD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenzhouxiangella sediminis|TrEMBL
MSKPQLSFEFFPPKNEKQQETFERSRDRLAALGPEYMSVTFGAGGSTRTRTFEAVRNIAE
HTGVPAAPHISCMSEDIDSIRDLLDDYRDNGIERLVVLRGDRPSGGGSGVFDYAVDLVRF
IREHYGDRFHIEVACYPEHHPESKTPITDIEHFRAKVEAGADGAITQYFFSAESYFRFVD
DARSAGVDVPIVPGIMPITNYSGLARFSRMCGAEIPLWIAKRIEAWEEAGDKASLRAFGE
EVVTRLCRQLLDGGAPGIHFYTLNQSKAPLALCRNLGLGKAAAGERDIA
>A0A0U3QDA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sulfonivorans|TrEMBL
MSPPSLIETHPNLTEAAPVALSYELFPPRSPAAAESLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPEELAEIIGDLLDTGVRGILALRGDQPKD
GAPLAAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYANLISRARRAGVTIPIIPGVMPLTSLRRVTRLGELTGVE
PAPELLARLAAADSDGERLRIGVRATVDLANAALEAGAPGIHIYTFNEHQSALEVLDKLA
LPRQSRSVGRRSATLRRQLAS
>E9F4X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075)|TrEMBL
MDKITDKIAALPADREYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSKRLVDKALEDAKALGIRNILALRGDPPRKEE
YCDAEDSEDDGQQDFTWAIDLVKYIRRKHGDYFCIGVAAYPEGHSDESHPQDQSLEHDLP
YLVDKVQAGADFIMTQLFFDISAYDHFEKTLREHPSGAFKTIPILPGLMPIQSYQMIKRT
TKLSHAKMPPAIMDRLDAVRGDDEKVKLVGVDIVSELIDQIRKIKNRTPGRRGFHFYTLN
LEKAVSFIVERTGLIPRESDNEEALIDDGTLAPPAIQVNGTRASTHSRTSRRHSSVGSDP
YNRVIVAGQPPSHPEWEATGQEAGVPAESINSRANTLAISEGEGVLGREATWDDFPNGRF
GDSRSPAYGEIDGYGVSLHMSVNQAVTLWGSPTSRQDVNNVFVRHIKGEISAIPWSEEGL
SPESSTIQSRLVEMNGKGWLTVASQPAVNGISSSDRTFGWGPVNGFVFQKAFAEFFLPSA
DWHMLAEKLKGSDYFDSVCFYAANAKGDFVSSDISGGRSTRTVAASTNAVTWGVFPGKEI
VTPTIIEEVSFKAWSEEAFGLWGEWAKVYGRGSESEKVLSGIRSDYWLVNIIHHDFIDRE
ALWKLLLE
>A0A0F7TFY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium brasilianum|TrEMBL
MHIREKLASKEAAGEPSISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGHLS
DLTCEMVGVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEATENGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSSF
VITQMFYDVDNFIEWVKKCRAKGINVPIIPGIMPIQQYASFIRRSNWTKTRVPPEWMEAL
EPVKNDDSAVREIGKRLIADMCRKVMASGINHLHFYTMNLAQATKLVLEELGLAPSDEAP
IQRALPWRPSLALGRRGEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGEVDA
YGVRLKGTNEQNIKLWGEPKSIKDLSEIFVRFLEGKLDRLPWSDSPISAEANDIKDLLVD
LNRRGFLTINSQPAVNGVKSSHPIYGWGPKNGFVYQKAYLELLVPPSLIDELVARIDKNN
DLTYHAIRKNGELRTNTHDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYRLGEDWS
KCHDSSSPSRKLIQQVMDDWYLVNIVDNDFHRNNAVFELFTDLEVKDLNVEVPGKPETNG
STEQNGAATKN
>A0A5J5EQC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerosporella brunnea|TrEMBL
MVHISQKLAESEAQKKPIFSFEFYPPKTGQGVQNLYDRMDRMHALGPQFIDITWNAGGRL
SNLTCEMVNVAQSVYGLETCMHLTCTGMPKEKVDEALKEAYKAGCTNILALRGDPPRENE
KWEADPNGFRYAKDLVKHIRKTYGDYFDIAVAGYPEGSEEGTEPELLLQHLKEKVDAGAT
FIITQMFYDVDIFLDWVKKCRAIGITVPIVPGIMPIHTYAAFMRRASWTKCHVPPRWLER
LEPVKNDDVAVREIGRDLVVEMCQRIIDAGIYHLHFYTMNLATATRMVLEGLNLIPTLDQ
VHPPLPFRPSLGFNRKTENVRPIFWKNRKASYVQRTQDWDEFPNGRWGDSRSPAFGEVDS
YGIGLRGSNESNIKLYGRPQCIRDVAETFVRYMAGKLSTLPWSESSITAEVDVIKDQLIS
LNRRGFLTVNSQPAVNGAKSSHPIYGWGPANGYVYQKSYLEVFVSPECLADLITNIERDP
EMTYYAVDKSGTLKTNSPDGPNAVTWGVYPGKEIIQPTIVETISFLAWKDEAYRLGQDWA
NCYTQDSVSRHLLTGMMDTWWLVNIVDNDFHREGKIFELFDNLEVKNLDETLEVADLVKD
LNLNGLNGEPKTNGGAVNGTTNGAAVN
>A0A1M6DSK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cycloclasticus pugetii|TrEMBL
MSLESYQKISFEFFPPKTEEGRVKLLNVSKALGQLDPAYFSVTFGAGGSTQQGTIDTVLD
IKKQGFSAAPHLSCVGSTKESIRNILSNYKDNGVDRIVALRGDIPSGTLDIGEFRYANEL
VAFIREETGDHFHIEVAAYPEVHPQAANAQTDLANFKQKVEAGADSAITQYFFNFEAYVR
FVEDCDKMAINVPIVPGIMPITNYSQLARFSDMCGAEIPRWIRKRLEGFADDRESIKAFG
TDVVSELSQTLLDYGCPGLHFYSMNQAEASLAICRNLGISAK
>A0A1F0FAY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eikenella sp. HMSC073A11|TrEMBL
MLHNTLSFEFFPTRTPEGREKQKITRKQLSQYQPEFFSCTSGAGGTTREGTMQTIRDILA
EGMAAAPHIPCVGLDAGELTDLLQEYKDLGIRHVVALRGDIPSGMGLGTTGLHHANELVE
LIRHRFGDWFHIEVAAYPEYHPQSRSAEDDIQSFVRKVKAGADSAITQFFFNADAYFRFL
DDVRGRGVEIPIVPGIMPIANFSKLARFADMCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCGRLLRHGAPGLHFYTLNQAGLSSTICQRLGY
>U7PAH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. PBN3|TrEMBL
MSTQQHPLGISFEFFPPNTEAGREKLIGVRDALAERSPRFFSVTYGAGGSTQDRTLDTVR
RVRESGITTAPHLSCIGSEKGQLRELLARYREEGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDYFEIAVAAYPESHPQAPSFERDVENFARKVKAGANLAITQYFFNADAYF
HFVERARALGVEVPIVPGIMPITNYAKLARFSDACGAEIPRWIRKQLEAYGDDSDSIAAF
GEEVISRLCQRLLDGGAPGLHFYTLNQAAPSLRIVDNIAG
>E9V1K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium Broad-1|TrEMBL
MVTGRGRSLAELINEGERSFSFEFFPPKDEAGEEQLWNAVRALEPYRPTFVSVTYGAGGS
TRDKTVAITGRIAAETELLPVAHLTCVGHTRDEVAAILDSYAAQGVAHVMALRGDPAEGP
RAAWTPTPGGLDYAIDVVRLAKERGDFRIGVAAFPEGHPSAESIEADADVLVAKARAGAE
FAVTQMFFRAADYFGLVDRVRARGVDIPILPGIMPILNLAAIRRQSELIGAEVPDEIVER
LTAAGPDPADIRAEGIAVAAELCQELLDGGAPGLHFYTLNRSKATLEIFAKLNVTV
>A0A7Z9R385|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lambdaproteobacteria bacterium|TrEMBL
MEIPFRESDTLENDMFMEPADDLQDYLKQKTTWSMEILPHNINDVSLIPEFVNEVYITMI
PGASCWETIQTAQQIKAVGKQAIPHIAARSFADVEELSACLSELQEAGIERALLIGGGNS
EPAGDFSCVMDMLKTGLLTKYGINSFDFAGHPEGNPDDPNSEFHLLEKLRWTEERGISTR
IVTQWCLDTDSANDWISGLREKGIRNPIHIGIPGPSTIKTLMRFAKVCGVKASTQVLRKQ
GLNLSKLMFVNKPDKIISELRGYDQLHLYPFGGIEKSAAWLTERQKAND
>A0A6I1GXW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. FT68W|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVNRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A7C2BQU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MCIRDRAMRRAEDMGLTEKTAILPGIIIPRSAGMLKYMNNNVPGIEVPDEMIQRMKDAAD
PKAEGIKITLELVDAVKNLSGVKGVHLQAIEAEGLLPDVIKAAGLLPRPKTD
>A0A7Y7DFU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclobacteriaceae bacterium|TrEMBL
MKITEHLKNAKSTLFSFEILPPLKGQSLKDLLEGIEPLMEFKPPFVDVTYHREEYIYKKH
PNGLLEKISTKKRPGTVGICAAIMNRFHVDAVPHLLCGGFTKEETENALIDLNFIGVDNV
LALRGDAPKTEGKFVPEKNGHHYASELVEQIVRMNQGKYLHEETETSCHTEFCIGVAGYP
EKHFEAPSLKFDLKYLKEKVDRGAEYIVTQMFFDNQKYFEFVKKVREIGIEVPIIPGIKP
ITTVNQITMLPRTFYLDLPDALMDELEKCKTNAEVKEVGIEWAIEQSKELIAAGVPSLHF
YTMSKADATYKIAKEVF
>A0A6N7AD96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MNKFLSLLESPTPLLADGAMGTFLHVHGVEHTHCFDELNLTDPARVADVHRQYIDAGAQI
ILTNTFGANRYKLGKNGLETRLAEINRAAVELAKRVVSASFKDVLVAGDVGPLGVRIAPY
GRVQLHEAREAFAEQVKALVESGVDLIVIETMTDVYETVEAIQAAKSAGTVPVAATMTFT
RDDRTLLGDEPAKVARALHEAGADVIGVNCSGGPAQLIRILRQMRQAVPEARFWVKPNAG
WPEHVGGRVMYAAAPEYFRDYVLEFWKAGANVIGGCCGTTPEHIAAMRKTLDTASAVSVE
PVQVSEVLQASEVSGAESPSELAQKLAAGKFIFAVEMDPPRGLATQKLVAGASLLKEAGA
DVIDVADSPMARMRMSAWAVCDTIQHRVGIETTLHFPTRGRNLLRVQGDLLAAHALGIRN
VFVVMGDPTSIGDYPEAADNYDLVPSGLIKLIKQGFNIGVDHSGTSIGQPTSFYVGSALN
LCTPEPETEIKNLKRKLAAGADFFLTQPIYEPAKAKAFLDRFAEAAGAPLDKPALVGILP
LVSVKHANFLHNEVPGIIIPEATRARMEKAGERGAAEGVKIAVELIHAIQEWGQGVYIMP
QFHRYDLVAEIIEAVKA
>L0L298|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomethylovorans hollandica (strain DSM 15978 / NBRC 107637 / DMS1)|TrEMBL
MAVTFREKLQSHRFIVTTEVTPPKGVETSYFLSDAEQLKQYVDAFNVTDNQKAVMRMSPL
AVGKLLKDAGHETILQITCRDRNRLALQSDLLGAWALGIRNICVMTGDHTTKGDHPDTKP
VYDLDSVQLLDTIRKLKLGYDLSGNSLERSPDFVVGAVSNTDPTQPMQHIKLRKKVSMGV
DFIQTQAVYDTKEFACFLEKVKDIDVPIIAGIIPLRSAKMARFMNENIPGIRVPDELITR
MEYAKEPVQEGLEIAVQSIRELKNMCRGIHLMPVGQHTHSKEILKMAGLAEGRTQNEQ
>A0A6G3QCK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID12488|TrEMBL
MALGTASTRTDHARTVRDMLASGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVSDTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPMAEWVPHPSGLTYAAELVRLIKESGDFCVGVAAFPETHPRSPDRDTDVTHFVD
KCRAGADYAITQMFFHPESYLRLRDAVAAAGCPTPVIPEVMPVTSVRMLERLPQLSNAAI
PSTLKERILTAKDDAAAVRSIGIEFATEFCARLLAEGIPGLHFITLNNSTASLEIYENLG
LHHPQRA
>A0A242SSE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASSLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A7D8UG24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHIADIIRRDGTTASFEFFPPKNPESSESLFGSIADLEPLRPSFVSVTYGAGGGTRELTR
DLVVRLKDQTPLDPIPHLTCVCHDERDIRSILEKYAEHGISNLLALRGDPPRDFNGGDPY
AGFAQAADLVRLIRRFNDERGAHPDPRGFGIGIAGFPEGHPGTPNRLVEMEHLKAKVDAG
ADYIVTQLFFDNRDFYDFRDRCRLAGIQVPIIAGVMPITSGKGMRKMAELALGARYPAPL
LRSIARAGDDDAAVRRVGCHWATEQCRDLLDHNVDGIHLYTLNKSNATREIYATLGVRDS
SQFS
>A0A2T5XYS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga leadbetteri|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVEAGADYVVTQMFFDNQKYFEFVDKAREAGINVPIIPGIKP
IAVKKHLNLLSQAFKIDFPQELVEAVEACKHNADVKQIGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A5C1I6A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter rubeus|TrEMBL
MKIPEHIANANGKTLFSFELIPPLKGQSIQGIYNAIDPLMEFKPPFIDVTTLREDFIYKQ
HPSGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENALIELEFLGIEN
VLVLRGDARLGDSSFVPTPNGHCYATELLQQVVNLNNGIYLHEDHGNTAKTNFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVEMGAQFIVTQMFFDINKYKEFVNGCRANGINVPIIPGLK
PITSSKQLVTLSKTFHIDIPDDLSDAIHACENEKAVKEVGIEWMINQCKELIAFGAPVLH
FYTMSNAGPTKRIAEAIF
>D4T7W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. aurantifolii str. ICPB 10535|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1H5E8N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 2131.1|TrEMBL
MLATGATSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSVTYGAGGSTRSGTVKATQD
IAAESTLTPVAHLTAVDHSVAELRNMVGQFADAGIRNILALRGDPPGDPMGPWVEHPQGV
RYAADLVRLIKEAGDFCVGVAAFPERHPRSQDWDADIRHFVDKCRAGADYAITQMFFDPE
AYLRMRDRVVAAGCETPVIPEVMPVTNVRQLERFSQLSDAKLPDDLKERILAAKDDPAAV
RSIGIDFATRFSAKLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>E3KZT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia graminis f. sp. tritici (strain CRL 75-36-700-3 / race SCCL)|TrEMBL
MAKKVVQLIESLKEDQVYFTFEYFPPKTIDGLSNLYARIQRMANLKPSCAHVTWGASGST
SDTSLEIAAMVQDQLAIPACLHLTCTNIQRTHLDQTLAQAKESGIVNILALRGDPPRGTE
HWIPTDHEFQHAIDLVKYIRKEHQDHFCIGVAAYPEGTTEFDQDQELNYLKQKVDAGADF
VVTQLFYDVDIFLNWVKACRNLGINVPIIPGIMPIQSYDGFRRLTALCKTNIPESIHSKL
IPIKGDDQAVRDYGVELSTQMIKRLQVNGFKSFHLCTLNLERSITRLVNQLGWSPGGIKH
CQPLLGPSVKIGTAEIVQGGLSVGWDEFPNGRFGDQRSPAFGLREGYSSSLTSAFSHLTT
DVHALWGTPTSLKDITQIFCAFTQGKLPSTPWSEEPLALETSSITPFLLKLNQNGWWTVG
SQPAIDGADSLDSVVGFGPQGGRVYQKSFVEFFVPHAHLEGLLSAVDDYNKEHSDGVAQL
RYYAGNCNQDQIRSNMAPGETNAVTWGVFRGAEVVTTTLIEAQSFKTWKKQAFEIWNDWA
ESFEPNSANQRLLNQIEDSYWLCSLIDHDFKQPEHLWSFLIAHQQRLLSHQSL
>A0A1E4EZB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonadales bacterium SCN 54-20|TrEMBL
MESQKKFVPTFSFEFFPPQTAEGIEKLRATRSQLAQLKPKFFSVTFGAGGSTRDRTLETV
LEIQAEGLVAAPHLSCIGATRENIRAMLEQYRSSGIRHLIALRGDLPSGMAQGGEFRYAN
ELVAFIRREYGNAFHIDVASYPEYHPQARTAQEDLRNFKRKIEAGADSAITQYFYNADAY
FDFVDSCEAMGINIPVVPGIMPINRFSQLARFSDTCGAEIPRWIRKRLEGYGDDSASIRA
FGLDVVTDLCARLLNAGAPGLHFYTLNSAGLTTTVWQRLGL
>A0A3D5B7E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MNGVLDLEAASIENVEPAEERSHLAQKLEAGKFVIAVEMDPPRGLSTHKLLAGASLLADA
GADVIDVADSPMARMRMSPWAVCHLVQSRFDVETNLHFPTRGRNLLRVQGDLLAAHAMGV
RNVFVIMGDPTAIGDYPDASDSYDLVPTGLIRLIKEGFNTGVDHAGGKIGQPTSFFVGAA
LNLCTNNLEREFKVLRKKLESGTDYFITQPVYEVEKARNFMKSYEDQFGKLPVPVIVGIL
PLVTDRHARFLHNEVPGIVIPEAIQDRIAGAGEDMAAEGAKIAVELIQDLKQDFQGVYFM
PAFNRFDMVA
>A0A512BLD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microvirga aerophila|TrEMBL
MSPLTLRPSRQDTCSIRVSFEFFPPKTPEMETTLWSSIERLAPLDPQFVSVTYGAGGSTR
ERTHATVSRLVRETNLRPAAHLTCVAATKEEVNDVIRSYWDAGVRHVVALRGDPVGGLGT
AYVPHPGGYQQACDLVAAIKGVGDFEVSVSAYPEKHPEAASLDADIDALKAKVDCGADRA
ITQFFFDNDHYFRYLDRVRAKGINISIVPGIVPVQNFKQTSNFAAKTGASIPAWLAARFD
GLDNDVDTRKLIAAAVAAEQVIDLVDHGVNEFHFYTMNRADLVYAICHLLGLRDHTVKAA
A
>A0A136HXD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. Nap_26|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEKTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVSAVPHLTCVDASREELKQIAKDYWDSGIRRIVALRGDLP
PGVNKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIS
QFFFDTSVFLRFRDRAAAAGVDLDLVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DDDDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRGNS
>A0A2E9AEQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MKIQDILTKTRTISFEFFPPREATGINAVLNKIESLQSYSPDFISVTYGAGGSTRKFSEE
LTTKAQIQYDVEVMAHLTCVGHTVKELDGILERLEGSTIENIIALRGDLPNNQQINLTAD
SGFEHASDLISHINRIYSFGIGAACYPEGHPEAVSFDHDIHYAKLKVENGADFLITQLFY
DNDDFFRFVDKARAIGINVPIIPGVLPVLSSNQIRKFTRLCGARIPLDLEMQLAKYENDN
DGARAMGVEYATRQVQGLWDSGVSGIHFYVLNRSYSVSKILDNLRLERSLP
>A0A2J7TLG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocella silvestris|TrEMBL
MSEHPTCELPRASRTHCPDIRVSFEFFPPKTVAMEALLWESINRLAPLGPSFMSVTYGAG
GSTRERTHQTVARLAREAVVRPAAHLTCVGASMKEIDGIVQGYWDAGVRHIVALRGDPPD
GLGATFEPHPQGYKNSCALVAGIKRIGDFEISISAYPERHPESLSLDADIDFLRAKVDAG
ASRAITQFFFENEIYLRYLDRLRAAGIDIPIVPGIMPMQNFKQTAGFAKKTGASVPQWLA
DRFEGLDDDPQTRRLVAATVAAEQVLDLVDHGVRDFHFYTNNRADLVYAICHLLGLRPKP
EQKEAA
>A0A1Q5E982|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB01249|TrEMBL
MALGTPSTRSDSAQSIRDLLSEGDRSYSFEFMPPRTPEAEAGLWKAIRKLESLSPTFVSV
TYGAGGSTRGRTINVTGRIAQETTLTPVAHLTAVDHSVAELRNILGHYADQGVRNILALR
GDPPGDPLGTWTRHPEGVCHAAELVALIKKSGNFCVGVAAFPEMHPRSSDSASDLRHFID
KCRAGADYAITQMFFDVDAYLRFRDLVSAAGCDTPIIPEIMPVTTLRSLRRIPELSTAAF
PDELAGRMLAAESDPAAVRAIGIDHATEMCRRLIAEDAPGLHFMTMNFSTVTTEIYRNLG
LAP
>A0A1F3KKD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWF2_43_11|TrEMBL
REETENALIDLHFLGIHNVLAVRGDPERSQKEFIAEPDGHTHAVDLVRQIIDLNHGRYLD
EELQNSTATNFCVGVAGYPEKHAEAPNQHSDLRHLKEKVDAGANYIVTQLFFDNSKFFDF
VDRCRAAGITVPIVPGLKPIAVKSHLIGLPKTFHIEIPDELVHLVEQCKSNREVRQVGVE
WAITQTKDLIRAGVPAVHFYTMGNPDNICQIARACF
>A0A5K8AEP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina ovata subsp. ovata|TrEMBL
MLNEKFVITIEVVPPDGPDPSELLKALGKLADLAFYGFSVATNPVAKPRMSAMALCALIQ
RHTGKPAILHLTTRDHNRLSLQGELWGARALGLQTVMVATGDFVALKDRHHTTTVRDADV
YDLVGMAREAGFKTGVVFDTHPESNGLPQAVGHLKRKVDAGAQFAVTQPVYDDAGADAIA
KATADINIPMIMGILPLRTPRHAEFLHSRVAGIAVPETLRHRMHAAADPVVEGAANAREM
LAIARQRFAGACIMPPFDHYEVLDEIL
>A0A8J7WQU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinocrinis puniceicyclus|TrEMBL
MALGIPSVRPDRAVTVRELLAQGAPTMSFEFSPPRDQKQDQQLWKALRRIECVGPDFVSI
TYGAGGSTRENTASEAERVAAETTLTPVGHLTAVNHSIGELRRIIGRYADAGVRNILAVR
GDPPGNPRGEWVKHPEGIEYASELVRLVKESGDFCVGVAAFPEKHPRSADWDSEIRHFVA
KCRAGADFAITQMFFDAEHYLRLRDRVVAAGCDIPIIAGLMPVTRAAQIERMVTLSGGTF
PKGVGERIHAVADDNAAVRRIGVEHTTELGARLLAEGVPGLHFITLNTSTATLEVFENLR
DAHALAGAARPVTAA
>A0A840YQD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas xinjiangensis|TrEMBL
MSNVDPLAPPLFADVAGDIDVSFEFFPPKSEKMEETLWDSVQTLSPLGPRFVSVTYGAGG
TTRERTHNTVARIARETAIPAAAHLTCVEATREEIDQVAQEYWAAGVRHIVALRGDSPRA
GEKYATHPGGYENAADLVAGLRKLHPFEISVAAYPECHPDSEHAQADLDNLKRKIDAGAN
RAITQFFFEPETFFRFRDDAAKAGINAEIVPGIMPVMNYASVVRMSAMCGTAVPGWMETL
FEGLDDHPAARQLVAATLTAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGVRPRAAA
GMIAA
>A0A0D2INK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fonsecaea multimorphosa CBS 102226|TrEMBL
MASEHDERLPTLLSSLPPSSYYFSLEFFPPKTSSGFSNLQARLARMATALRPLFVTVTWG
AGGSTATKSLELAEVCQRQIGLTTVLHLTCTNMRRHMIDEALEEAKEIGIRNILALRGDP
PREEYKDATSTDESESGSGGSGTESNQEFTWAADLVRYIRRKHGDYFAVGVAGYPEGHAD
ESHPEQGKQSVEHDLPYLAEKVAAGADFIMTQLTYDIEAYAAYEKRLRGYTGQDGKKLFD
KIPIIPGLMPIQSYQIIKRITKLSHAKLPEKISQRIERVKSDDEAVKKVGVDILSELVEE
MKTLPQPEAVPRGFHFYTLNLEKSVSFILERTGLIPAISSEGSVEDKDGDSESDSDVVVD
DSKQETPAIVTTGPVENGNQNGQQSSSFTRRRRSSVNAQPHNRVITDGRSEPRTQSRRPD
SDSDPPGLEPNPNLKLTSQHSARDRGTGIPAASPTRKHSLLISEGQGSLGREATWDDFPN
GRWGPSHSPAFGEIDGYGPSLKVSPLMARKLWGYPRSREDVTKLFRRHVLGDLVAVPWSD
DIDPDLASPGAASADGSGNSSALRAETDVIRSELLSLISSQNYWTLASQPAVDGAPSSDP
VFGWGPPGEGYVFQKAFVEFFCGRDEWEEKLRPRLMKYGSDVLGWMKTDAEGVFESSELI
ARDQARKKKAAAVDTEKENTNPASLVQFADQRPVPSASSSSPENTVNAVTWGVFPSREIL
TPTIIEAESFRAWAQEAYAIWNEWKRCFPRGSQEALFLEKMGKENVLVNVVGQSFRGGHG
GGKGEGASLWRILLAEDGDAK
>A0A1V5JSZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistetes bacterium ADurb.Bin520|TrEMBL
MARHIKDLFAAKRPVISFEVFPPKPGVRVDGLLDTLGALRELNPDYVSVTYGAGGSSRAR
TVEIASAAQNRWGLTALAHLTCIGQTRRDLEEVLEELEQEGITNVLALRGDPRDDVPPLD
PPPFRYAADLVAYLRTSRKGDFCVGAAAYPEGHVECDDLEADLRHLKEKVDAGVDFLVTQ
LFFDNEIFFRFMDRLRELEIGVPVSVGIMPVLNSRQIGRMVSLCGASVPPKFARILARYE
NAPEALRQAGIAYATEQIIDLLSWGVAGIHIYTMNKPEIAQDIMKNIGVVRETLERGAKE
EGPS
>A0A6G1P3U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium dahliae VDG1|TrEMBL
MHIKEMLADAERDGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIA
ELTCEMVTQAQSVYGLETCMHLTCTDMGLDKVNDALRKAYKAGCTNILALRGDPPREKEK
WVAADGGFEYARDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGATF
IVTQMFYDADNFVRWVGKVRERGITIPIVPGIMPIATYASFMRRAKHMNCSVPQEFMDAL
EPVKNDDNAVREVGKVLVAGMCRKILAAGIHHLHFYTMNLAQATRMVLEELNWMPTSERP
LKQALPWKQSLGLGRREEDVRPIFWKGRNKSYILRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNIKKWGEPQTVQDIATLFVRYLRNEIDCLPWSESPLTNEADPIREDLIA
LNKRGIITINSQPAVNGVKSSHAVHGWGPKNGYVYQKSYLEMLVHPDLYPEIISRIEKHP
DMTYYAVTKSGNLKYNAPSDGPNAVTWGVFPGKEIVQPTIVEGISFVAWKDEAFRLGLDW
AHCFEQSSPSRVLVELNNDFHQQREIFDLFEGLSVKEYDDIKPVAKDVAPDAVSAPTNGT
TNGIAVPAA
>A0A7U9NHI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKITEAFERGEFVVTAEVGPPKGFHIEHMLEEAKTYLSGITAVNVTDNQSSVMRLGSLAT
CKALKDEGLTPIFQMTCRDRNRIALESDLLSAALFGIENLLLLTGDHTTLGDHPQAKPVF
DLDSVSLIHAVKQMESGVDLGGNELVGEPPKFAKGAVVSPCSDSVDVQLAKMERKVAAGA
EYFQTQAVYEPEKFIQFMEKAKQFGKPVQLGIVIPKSVGMCRYMNANVAGIHVPEEMIEE
LKADKEKTKAGITGVEIAARVIKECKPYCQGVHIMAMGWESKVPELLSQAGI
>A0A7X5ELW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIIDRLNEDKIHISFEVFPPKTDAGFDKVLDATDKIAALKPSYISVTYGAGGGTSKNTA
RIASHIKDDLGVLSLAHLTCASSTKEEVRSVIANLRQLGIENILALRGDIPEGMVFPTED
RFRYAWELVEEIKKYGDFCIGAACYPEGHVENEHKADDIRFLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSATQMKRSQELSGTVFPRRFLALLDRFGSYPE
AMMQAGIAYATDQIIDLLANGVKNIHIYSMNKPEVAEKIMSNLSEIIRC
>A0A1L6ZJR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus safensis|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSIEEIKR
SFREQLYILLNEEPDGLLLETYYDIEEAKAVLQIARKETTLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVSINCRLGPYHMIQALEGVPLLENSHLSVYPNSSLPSLEAGRLVY
DTDNDYFRKSALDFRNQGARIIGGCCGTTPQHISAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKDAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMAKAGEDKEKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKESNVHVNYH
>A0A1S2Q0W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces monashensis|TrEMBL
MTTFSFEFFPPKSAAGERTLWQAIRRVEALRPDFVSVTYGAGGSSRDRTIEITRRIATQT
TLRPVAHLTAVGHSVNELRHIIGAYADAGIKDVLALRGDPPGAPRGPWVAHPDGFSHAYQ
LVELVRSLGNFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFDVEDYLRL
RDRVAAAGCDIPIVPEIMPATDIRQVRRFAELSDAAFPEDLAHRLESARDDPAAGHRIGV
AYATAMAERLLAEGAPGLHYITLNRSTAALDIHRNVISSRSIRVA
>A0A516H301|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrovibrio terrae|TrEMBL
MTTLTEPNAHAARRSGPLKVSFEFFPPKTPEMEESLWRSVMRLAPLSPRFVSVTYGAGGS
TRERTHNTVVRILNETGLKPAAHLTCVGASKGEVDEVAQHYWQAGIRHIVALRGDAPEGS
GGFQPHPQGYANSTDLIAGLKKIADFEISVGCYPEGHPDTASPRIELEHLKRKADAGATR
CITQYFFDTDVYFRFLDRARSAGITIPIVPGILPVTNFRQVTKFSAACGASVPAWMADQF
DGLDDDPETRRMVAAHIAAEQCRRLLAAGIDEFHFYTLNRADLTYAICHVLGVRPKPAIA
GEVAA
>A0A524JX83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chrysiogenales bacterium|TrEMBL
MAKVIDWLKQNDKLMFSLEITPPDRGKSVDDILSSIETMMPFDPQFINVTYHQPHVVYEE
KDGVITRRPRRKKPGTVGICSAIRNRFQVEPVPHLICGSFNRYETEDTLIDLHFLGIENI
LALRGDPPPGQPRYIPEKDGHNYAWQLVEQISQLNRGQYIDELEDPFPTHFCIGVAAYPE
KHFESPNLEKDLFYLKKKVDMGAEYIITQMFFDFRQYRTFVEKARAIGIQVPIIPGLKPL
VSKKQILTIPSLFHVNIPAELVALIEEARTREQEFANGVRFLARLAEQLIDYGVPGIHVF
SMGQGRAAKAFLETVFAGKR
>A0A3D5LXB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKIRDILNKDTATISFEVFPPKKSTDFGNVEAAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGEIQKQHNVPTVAHLTCVCADRGSIGAALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKENGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITEPIIPGIMPITRGVQVRNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNISEILKA
>A0A2T3E7U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. JAB6|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMG
VQNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVTMFREYMKKVRDLGLHEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRTDALVAERLHQISEGREENQQAMAEIAA
HHTPQQAH
>A0A0D2IUC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhinocladiella mackenziei CBS 650.93|TrEMBL
MADDRLPTLLSSLSPSSHYFSLEFFPPKTSSGFANLHSRLARMAAALRPLFVTVTWGAGG
STTTKSLELAEVCQRQLGLTTVLHLTCTNMKRSAVDDALESAKEVGIRNILALRGDPPRE
EYKDTDELENGGFGTEDCEEFAWAVDLVRYIRRKHGDYFSIGVAGYPEGHADESNPEAGK
QSVEHDLPYLAEKVGAGADFIMTQLTYDIDAYRAYEKRLREYVDTDGNKLFEKIPIIPGL
MPIQSYQIIKRITKLSHAKLPEDTAKRIESVKSDDEAVKQVGVEILSEIVEQIRTLPQPE
GVPRGFHFYTLNLEKSVAFVLEKTHLIPPFSEPSPGDSSDSDAIVEDVKKSIHFAPTFAN
GSSTGERGQTARFSRRRASSMNAQPHNRVIMDRPSRSPGQSRRDRSAELTRPILLQHEAP
DRGTGIPASDPTRKHHLMISEGQGALGREATWDDFPNGRWGPSNSPAFGEIDGYGPTLKV
GSITARKLWGHPKSTRDVTELFRRHVIGELEAVPWSDEVDVDGASGGGDGALRAETEVIR
RELLALIEKKGYWTLASQPAVDGVKSEDDTFGWGPPGEGFVFQKAFVEFFCPRQEWENHL
KPLLIKFDSEHVGWMKTDANSVFESSEAVVQKESTDKPTSKHTPGVSTVNAVTWGVFRGK
EIITPTIIESESFRAWGEEAYSIWSEWKRCFPRGSEEEQFLECMRLDSVLVNVVGQNYIG
GHGGDGAQLWKVLLQDSPIG
>J3D5D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp. CF318|TrEMBL
MNLPLSFEFFPPKTPEGAAKLRVARQALYAHKPEFCSVTFGAGGSTQEGTFGTVKEILDE
GVAAACHFSCVGATKATVRKQLAELRAMGVKRLVALRGDLPSGYGAGGEFHYASDLVAFI
REETGDAFHIEVAAYPEVHPQARSADADLQAFVKKVKAGADSAITQYFFNADAYFRFVDD
AQALGVDLPIVPGIMPVISSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVV
TGLCEQLYAAGVPGIHFYTMNQAAATTDIIGRLQRA
>A0A2M7IBM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophilales bacterium CG12_big_fil_rev_8_21_14_0_65_61_21|TrEMBL
MAEHIFSMEFFPPKTAEGAAKLRETRRQLAQLKPRFFSVTFGAGGSTRERTLETVLEIQS
EGLGAAPHLSCIGSTEENIREILQTYKAHGIRHIVALRGDLPSGVADPGEFRYANELVAF
IRKETGDWFEIEVAAYPEMHPQARNYQQDLLNFKRKVEAGANAAITQYFFNADAYFQFRD
ECLALGIDIPVVPGIMPISNYGQLARFSAMCGAEIPRWLAKKLESYYDDSASIKAFGLDF
MTQLCDRLLTNEAPGLHFYTLNQAGLTSTLWQRLGLSR
>A0A4Q3TAU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacteraceae bacterium|TrEMBL
ADPVRVSFEFFPPKTDKAEETLWQAIRRLEPLNPAFVSVTYGAGGSTRERTHRTVQRIIS
ETGLRPAAHLTCVEASREEVDQVIADYKAIGVDHIVALRGDPPGGAGIGGVYEPRADGYA
NATELARAISRVGGFDITVGVYPEKHPESPSFAHDIDVLKAKVDAGATRAVSQFFFDIDA
FLRFRDAVRAAGVTIPLIPGIMPVSNFTGLMRMCGSCGASVPDWLHAHFDGLDDDPETRK
LLAASVAAETCARLQEEGFHDFHFYTLNRADLVYAICRVLGVRAVGAA
>A0A2G2F4A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fluviicola sp|TrEMBL
MKVTDHIKGAKSTLFSFEILPPLKGKSIQSIYDGIDPLMEFKPKFVNVTYHREEFIYKER
ENGLLEKIAIRKRPGTVGICAAIMNRYDVDAVPHLICGGFSKEETENALIDLQFLGIDNV
LALRGDSIKTESNFRPHKYGHQFAQQLIEQVVEMNSGTYLMDDIQLEPTDFCIGAAGYPE
KHFEAMNLNFDLENLKKKVDAGAEYVVTQMFFDNQKYFDFVKACRAIGITVPIIPGLKPI
KSMNHISFLPKFFHIDYPEALSKELLKCKSNADVAQVGIEWGIQQSKELNAAGVPCIHYY
TMSNSVSVKAIAKEIF
>A0A1Q3A7M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygosaccharomyces rouxii|TrEMBL
MSIRELYESKDGPTLSLEFFPPKTETGKQNLLERIERMTALGPLFITVTWGAGGSTAEKT
LELASLAQKNLNIPVCMHLTCTNMDRNIIDDALTRCKAAGINNILALRGDPPIGQDWSDL
EASQSEFKHAVDLVKYINYRFPSEFCIGVAAYPEGHCEGEAEGSEQNPWKDLPFLKEKID
AGADFVITQLFYDVDKFLHFEQMFRQHISTDLPLIPGLMPINSYLLFNRAAKLSHASIPS
SVLQRFPPEIQADDDAVKSLGVDILIEIIERIHTATQGRVKCFHFYTLNLEKAVAKIVAT
SPTLSNVLDGVEDENEEAATSEPEEQDKEGDIVLEDANVKGLIEENRKRRRQSSNVSNLS
SDLTSNRVIIGKKNQHGVGAPTRKVVISISQGSGTLGRDATWDEFPNGRFGDTRSPAFGE
IDGYGPTLKVSNKKAYELWGQPKAIQDLQTIFIKYLEGSIEALPWCDLGLSPETGLIQEE
LIQLNDRGLLTLASQPATNGSPSTNKIFGWGPAYGVVYQKAFVEMFVPKNVWENGGMKKS
IEQYGRAKLTYYANDSQGNFETNLEPNSSNVVTWGVFSDSQVVQSTIVSEESFKAWSDEA
FSIWLEWAKLFPRNTPTNSLLRQVHQEYCLVSIVHQDYIHPDELWEIILSLN
>A0A411ZGL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altererythrobacter insulae|TrEMBL
MSPTLDQMQEARTALDSPLFKGLPGDIDVSFEFFPPKTDKMNETLWHSVETLAPLGPRFA
SVTYGAGGSTRERTHEQVVRIQNEAGIPAAAHLTCVAATKDEVNEVARHYWESGIRHIVA
LRGDAPDGGGQYTPHPGGYANAVELIAGLKEVADFEISVAAYPEVHPDSPDAQSDLDNLK
AKFDAGATRAITQFFFNTKCFFEFRDKALAAGINGEIVPGIMPVVSFAAVQRMSGLCGTD
IPHWMEGLFDGLDDRPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYSICHML
GMRPKGGA
>A0A1T5DP97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MIKEELDSRDCMLSCEVFPPKKEDAFTKVFNVLDSIAECDPAFISVTYGAGGSNAGKHLE
ISSYIQNKLKIETIAHVTSVGFNKKDLDDELDALEKEGVYNILALRGDRPADMTDEKYNS
REFEHAVDMVKYIRETGRKYCIAGACYPEKHFEAPDKLTDMFHLKQKVDAGCDFLISQLF
FDNTFFYRFLELAARNDIEVPVHAGIMPITSAQQLGHTVSLSGTSVPKKLSDLIARYGDD
PEDMKKAGIEFAVDQALDLASHGVHGIHVYAMNKPELCREIFTAVRQNI
>A0A7C4TVL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Margulisbacteria bacterium|TrEMBL
MSLEKALKENKFCITAEIFPPKGVDISSSLNKARTIKKYVDAINVTDNQRAVMRMNPISL
CHKLVSNGIDAVLQISCRDRNSMGLSSDLLAAYSFGIRNILAVTGDYPVRNGKMLTKPVF
EMDSVQLLDLVKKLERGFDFNGAKLESSPKFIKGAVVNPSSDMMDFQIMKLKKKVDLGAS
FIQTQVVFDIDSFKKFRDKTANIKSKFLLGVFPLKSFSVAKFMAEKVPGVKVPTKILDRM
EKSKDPFREGVEIVVEIINSLKSYCDGIHLMTMNDENLVKDIVEKIK
>A0A7W5F9S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides albus|TrEMBL
MDLQQRISDRAGEILLFAVTPPRVTTDPERVQQIAEVTLERIRPLEVDGLILYDIDDESD
RNPEERPFPFVRTLDPADFLERNLAGLDVPAVVYRATGKYDEPTLRDWVKTQDPGKALSV
FVGASSGEKRVATSLRRAQQIRNETNPDLLLGAVAIPERHTAKGDEHLRLIAKQEAGCSY
FVTQVVYDVNAAKNLVSDYRYECDARGLQPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENELRHATDTLDASLEQAEATALELMSFCRQLGVPFGINIESVSIRKVEIEASVRLAERL
RGKLER
>A0A3B4T8C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Seriola dumerili|TrEMBL
MVNQVQRGEGSWQSCKSDSSGASNSGGESSKESSRCSTPVLDADRSDRLRDKMRRRMESG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKDKITGYLAKAKHLGLKNIMALRGDPVGVDWEEEEGGFNYAI
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEQDLRHLKDKVDAGADFVITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIQQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWTEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLQMWGEELMNEESVFEVFTCYITAQPNRSGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPSINGKPSADPVVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGRNLTNAPELQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPETLSDLTVS
E
>A0A146HN03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycena chlorophos|TrEMBL
MKLTEKIQALKPSRPFFTLEFFPPRTDQGFENLLPRISRLSALNPLAISITWGAGGSTKE
RTLELAGVSQEEYGLDTVLHLTCTNMAQGMIDEALQEAKQRGITNILALRGDPPRGEEEW
TPIDPRFKNGTDLVKYIRSNPDYASHFCVGVAAYPDGHTGQLDDERAEIEYLQLKVDAGA
DFIVTQLFYDVDGYFQWEKKVREAGITVPIIPGIMPIQTYASFLRLTKLTGARVPESVLQ
ALEPICNDDQLVKEYGVTLAIEMIKRLTEEGQVRGVHISTLNLEKSVQRVIEDLRWSEIP
SSPLINHNKLIEEIPQLNDLTITPSTAATSATLGLANLPIAVETEAGRGELNNASSWDDF
PNGRFGDFKSPAFGSIDLWGGPAIGPADVLRHCGHPQTHADLTAIFLDYLHSRIPITPFS
PTPLSPESLSIMPHLERLTKAGWWTVGSQPAVDGARSDDPVVGWGPRAGYVFQKGFVEFF
CTEAEVDRIEQKALDVGWVHWFAGNKKGECRGNVPEGGRNAVTWGVFPGQEIVQTTIIER
ESFLTWKEEAFSIWADWASLYRPGSVERRLLEDVADERWLVSVVHHDYRDPKALWTFVLD
A
>A0A6N4PX59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira kanakyensis|TrEMBL
MHISQVLGKKQTTISFEFFPPKNEEASADLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEETGLTIVSHLTCVGSTKDEIKEILKRYEKSGIHNIMALRGDPPKGQTEFQQT
ENGFAYAGELVGFIKKEFPKMGIGIAGFPEGHPSTPNRLKEIEYLKWKVDQGADYICTQM
FFNNHYFYDFVERCEIAGIKVPIIAGIMPVTSIKGMARMAELSLGTSFPAKLLKSLSRAE
DDSYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRKIYESLGIRNFDTIG
>A0A560W6W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marihabitans asiaticum|TrEMBL
MTQQHGTPERSATITRRLWDARPAISFEFMPPRDDVGEAVLWEALEGLEPLRPDFVSVTY
GAGGSSQDRTLRITQEISRRTSLTAMAHLTCVSQSVSDLRQVLQGYAAAGIDHVLALRGD
PPGDPRGEWVAHPGGLSHADELVRLIGETGGFEVGVAAFPDVHPSSASLADDIDTLVRKA
DAGATFAITQMVFDVDSYLRLRDALAARRDLPVVPGLMPVTSVKQVDRMAQLMGTPLPER
VLERLRPVQNDRAAVRAVGVEIATELASRLLAEGAPGLHFITMNRSTATLEVHENLAGQL
AAASRPVEAITR
>A0A1Q2CUP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus flavescens|TrEMBL
MLRTDPSPATVGDLLASAHGPLFSFEFFPPRSEEEEPILWRAVDALAPLAPDFVSVTYGA
NGSRRDRTIRATRWIAESGGPLTVGHLTCVDQSKADIAEALDAYREAGVTNILAIRGDMP
GGGEWEAHPDGLGNATELVRFIREQGDFCVGVAAFPNPHETSDDVDLDARILTQKVEAGA
EFAITQLFFDAGRYGELVERMRALGCTVPIIPGIMPLTVITQIERFADLSGRALPEGFVS
RLRAAGSKEEVREIGLNAALQLCRDLLAAGAPGLQFFTQNRSKATREVLARLKDEL
>A0A1S2VPZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arsenicibacter rosenii|TrEMBL
MTKITEHIRNANGKPIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PMPDGTIKRIITRKRPGTVGICSAIMHRFTVDPVPHVLCGGFTRDETEDFLIDLHYLGID
NVLVLRGDPAKPFNTFKPKDNGYSYASELVEQVVNMNHGSYLHEGETALAPSNFCIGVAA
YPEKHLEAIDFETDMQYLKHKVEKGADYIVTQMFFDNQKYFDFVDKCRSMGITIPIIPGL
KPLSTRKQLSVLPRIFHLDLPEDLVKSVEACESDAQAREAGIEWCIQQCRELVAGGAPVL
HFYTMGKSDNIMKVAGAIF
>A0A1J4QVJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio barjaei|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSTPTMEETLWKSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSETGLVAAPHLTCIDASRDELIDIAEDYWSNGIKNIVALRGD
IPAGGGQPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAGMNKVKVPGWMQKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQV
>A0A246AP11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium JJC|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERKITRMRPGTLGICSAIQHKYNVDTVPHVLCGGFSMEETEYLLVDCMYLGIEN
VMALRGDAMKGQQYFEPSPGGHKNAMDLVNQMNDLGRGKYLHDDGKICDEQNKFCIGVAG
YPEKHIEAPSMNYDLKWLKEKVDAGADYVVTQMFFDNKKFIEFVKQAREIGINVPIIPGI
KPIAVKSHLQMLPKVFKIDLPEDLISAVEKAKDNTAVKQIGIEWAINQCRELMEFGVPVL
HFYSMGKSDNIKRIAREIF
>A0A5M3N1U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coniophora puteana (strain RWD-64-598)|TrEMBL
MKLTDKIANHDTRHPFYTFEFFPPRTDQGFENLLSRISRLQTYKPLAVSITWGAGGSTKD
RSLDLAGITQADYGIDTVLHLTCTNMVPGLVDDILKAAKERGIQNILALRGDPPRGAEQW
TPTDPRFKCAIDLVSHIRSTPEFASHFCVGVAAYPEGHPDHDPADGDPSEREIDVLKEKV
DAGAEFVVTQLFYDTSKFLTWINKVRERGIIVPIIPGVMPIQTYDSFGRVVKLCGVKIPP
ALKADLEPIRHNDQLVKDYGVQLTIDTIRRITSPDATPNGPAVPGVHFCTLNLEKSVQLV
LERLQWTDASPRIKNRLIAETAGPIIHAEEPSSGLVVTPITATDSATTALSHKVPENEPH
REGDSAATWDDFPNGRFGDVKSPAFGAGDQWGGLGLSLHTPPSEWGKPKEIRDLTNMFLS
YLKDSVRTPTTPFSRFPLSPESETILSHLEVLTHRGWWTVCSQPAVDGARSEDEVLGWGP
RGGYVYQKGFVEFFVPEEDVGPIQQAIETQGEGLIHFFASNNEAGEGFLTNVPEDGRNAV
TWGMFPGQEIAQTTIIERESFLAWKEEAFSIWEDWASFYPPGSPERNCLESIRKRWWLLS
IVHHDYRRPDALWSFLEGIARTSARTSA
>A0A3M4WYB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. fraxini|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>A0A0L8LLV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces decoyicus|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVKHPDGVGYAADLVRLIKESGDFCVGVAAFPEMHPRSRDWDTDVAHFVD
KCRAGADFAITQMFFYPEDYFRLRDRVSSAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A3D0V169|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter sp|TrEMBL
MALFNFRLKSDAPIATPAAIEALLANYSIEVMPRTAEKVEDFRALLPQTTRVYVAHIDGT
PIEDMVATAKRLKDQGFTVMPHFPARIIKDKVMLEEWISRYQNEAGVRQALLLAGGVAQP
HGVFNSSMQLLESGAFGDFERVHIAGHPEGNRDIDPDGSDKMVMQALHWKQSFSKTTDAK
MAMATQFCFEADPVIAWTSRLAAEGIDLPIHIGVAGPAKLQTLIKFAIACGVGASLRVLQ
KRAMDVTKLLLPYEPNDFIAALAYHKAAHPNFGIEAVHFFPLGGIKPNAQWAIDNGGASG
AAALNS
>A0A1Z4JJV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya boryana NIES-2135|TrEMBL
MTYPQISQPLGHAPLSAFRTAARNGEFLVTAEVAPPKGTDPTHMVQMAQVLKGRVHAVNI
TDGSRAVMRMSSLVSAALLLQQGIEPVYQVACRDRNAIGLQADLLGAHALGIRNVLALTG
DPLKAGDHPESKAVFELESVRLLQMISKLNGGSDWNDKELTDGETDLFVGAAVDPQCASW
SGLQRRFERKIQAGAQFFQSQLITDFERLDKFMNEIAAGCNKPVLAGIFLLKSAKNARFI
NRAVPGVNIPDHIIDRLEKASDPLREGMVIAAEQVKLAKEVCQGVHMMAVKREDLIPEIL
DLAGIPAIAKQTELISAVTLS
>A0A2D6FIM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobium sp. ARS6|TrEMBL
MGSALQRSLEAGAVTVTAEVMPPRGGDPSHTLAMASLLRDWVQAINVTDGSRAVMRMSSL
AVCRLLLDAGLEPVLQMAGRDRNRIGIQADLLGAHALGIRNLLCLTGDSVKAGDQPDVRP
VHELESVRLLQQVSAFNRGEDPVKESLPDGPTALFAGAAADPHCASWSGLRRRLERKRDA
GARFVQTQMVMDPQVLERFCQDMATPMELPVLAGVFLLKSARNASFINKKVPGASIPDNL
IARLEAASDPAAEGVAIAAEQVRQFSGIANGVHVMAVRAEERIPEVLERAGLSSQRS
>A0A416V8T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. AF16-5|TrEMBL
MKIRDLITQDKATLSFEVFPPKKDTDFADVEAAALGIAAFKPDYMSVTYGAGGSTKGHTI
QLAQEIQEKYDVPTIAHLTCVCASKEGIKTALADMKNAGIENILALRGDIPKNYDGQVFA
EFSHASELVELIKETGDFCVGGACYPEVHPDSANKHEDIIGLKKKVDAGCDYLTTQMFFD
NNIFFNFMYRIREAGISVPIIPGIMPITRRVQVKNAVKLSGCNVPERFKSIVDAFGDTEA
AMRQAGIAYATDQIIDLMANGVKHIHVYSMNKPEVAAGIQKNLSEILKI
>A0A5C7ZXH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVIDHLRNADRTLLSFEILPPLKGKDIRSIYEGIDPLLEFKPSFINVTYHREEVVYKER
GQGLLQKIRIRKRPGTVGICAMIKAKYNIDTVPHLICGGFTKEDTEDALIELNFLGIDNV
LALRGDAIKSEPAFIPERDGHAHATDLIRQIAGLNKGKYLHDEEQEAAPTDLCIGAACYP
EKHAEALNLATDIAYLKQKVDAGADYLVTQMFFDNTKYFRFVELCRAEGITVPIIPGLKP
LTTLKHIAFIPKTFAIDLPQPLATELMKCRSDADVKRVGIEWSIAQTKELIAQRAPCVHF
YTMGRSEAVRSIVGAVY
>A0A556W2B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp|TrEMBL
MSRQEHPLGISFEFFPPNTDVGRDKLMRTRDQLAACYPRFFSVTYGAGGSTQVRTRNAVR
DISQSGVTTAPHISCIGSDKAQLRDLLAEYREEGVDSLVALRGDMPSGTASMGELRYANE
LVEFIRTETGDHFEIAVGAYPESHPQAPNLDKDVANFARKMKAGANMAITQYFFTADAYF
HFVDKARALGVTQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYADDSEAIADF
GSDVVTRLCERLLDGGAPGLHFYTLNQSAPVKRIMGNLTG
>A0A348PRA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTEHIKNAEKTLFSIEVLPPLKGQTINSIYETMDQLMPYNPAFVDVTYHRQEVVYREV
EKGLMKRHAVRKRPGTVGICASLMNKFNIDTVPHIICGGFSKDDTEDALIDLNFVGIDNV
LVLRGDPEKGTGIFKSEPDGHAYASELIGQVIEMNNGNYLDQDLRDTSKTNFCIGVAGYP
EKHFEAPNLKSDLKYLKKKIDLGAEYIVTQLFYDNSKYFEFVDKCRAAGINVPIIPGLKP
ITSQKQLSVIPHYFHVNLPDKLVDEIEECKTPEQTRQAGVRWCIQQSQELIEAGVPVLHY
YSMGKAKSIQEVAEEVFGS
>A0A1T4RMK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillum multiglobuliferum|TrEMBL
MSQSIDFSFEFFPPKTPQGQEKLKVVRDQLAAMNPAFFSVTYGAGGSTQERTIQTVLEMR
EAGINTAPHLSCVGSSKESLRELLNFYIVKGINRIVALRGDLPSGMGSAGELRYANELVE
FIRAETGDHFHLEVAAYPETHPQASNFEADLLNFKRKIDAGANSAITQYFFNPDAYFYFV
ERCQKLGITAPIIPGIMPITNYSNLARFSDACGAEIPRWVRKQLESYGDDSASIRQFGEE
VITRLCEQLIAGGAPSLHFYTMNQAEPNIAICKNLGF
>A0A4Y6QVH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. NIBRBAC000502771|TrEMBL
MPAPNRAASLELIKNFSLEMTGKDIPALIEAKDGIPPGTRINVTFLGNEDLEMRVAAAKA
ARDLGFIPVPHVSARRLNSKGDFEEFLGRLQEVGAAEHLFVVGGDPAEPEGPYGDSLALV
NTGLLQQYGVREVGIGGYPEGHPDIRKEDLWRSLEDKSAALAAQGLKASIITQFAFDTAP
VAAWIDEVRARGIQAPIRVGTPGPAGVKRLLGFARRFGVGANAMIVKKYGFSLTNLMGDA
GPDRFVNDLAAVLADHAPRQDHHLPAQVGLHFYTFGGLLATANWVRHFTEEG
>M9MLL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter thailandicus NBRC 3255|TrEMBL
MIRSIGQVRTNLMTESSIELLPSRILELSGVLPDLDRGSRVFVTWLPGVPFADVLAACDL
LKLCGYLPVPHVAARSIRDTQHLRNICTALIERDIPRMLLIAGGADKPAGTFTDTVQVLE
TEIPAQAGIRTVYVAGHPEGHPQATEKQLEQYLLRKQELARAQGLNMQIVTQFCFDAAPI
LNWEKRLRAAGVRLPINLGVYGLTTPRTLVRYGLACGVGQSLRFMQKQRWKLHRWFTPCN
PKDLVDAIAGSIAETPDTLFHGLHFYPFGAIARTLEWRRNFSCSTYGEPS
>A0A2Z2P704|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyrobacter sp. CACIAM 03H1|TrEMBL
MTPTLDQLQEYRTATDTPLFSGLPGDVAVSFEFFPPKSAKMEEQLWDAVTQLKPLGPSFV
SVTYGAGGSTRERTHATVARIIAEAKLPAAAHLTCVAASKAEIRDVAEQYWEAGVRHIVA
LRGDAGEPGAPFTPHPEGYASAAELVAGLKAIAPFEISVAAYPECHPDATSPQDDIDNLK
RKLDAGATRAISQFFFSAETFFRFRDQCAAAGIDAPILPGILPVTNVAQARKFAGACGAA
IPAWMDGLFEGLDEKPAARQLVAATVAAELCRRLYAGGVRDFHFYTLNRPELAYAICHLL
GKRPQETGQ
>A0A1B8S5D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leisingera sp. JC1|TrEMBL
MTTPKISFEFFPPQNLEASFRLWDTVQVLSPMDPRFVSVTYGAGGTTRTLTRDAVATLHK
SSGLNVAAHLTCVNASKAETLEIADQFAEAGVTEIVALRGDPPKGEGKFTPHPEGFANSV
ELIEGLKARGDFSIKVGAYPDRHPEAADQAADVEWLKRKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDGTKLTPGILPIENWKGARNFAKRCGTVIPEWVENAFEKALRDGREELLA
TVICTELCSDLLEGGVDKLHFYTLNRPELTRDVCFALGVTPKVSLQNVA
>A0A1W9T765|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium 4572_117|TrEMBL
MPKRVVDHIMESKKTLFSFEILPPLKGKDINLIYDVIDPLMEFKPKYLNITYHREEVVYK
RHKSGLLERKTVHKRPGTVAIAAAIKYKYRNVNVVPHIICGGFTKEETENALIDLHFLGI
RNLLVLRGDALSADKDFKPEIDGHSNALDLVEQIGNLNKGRYLDEELENTTKMDFSYGIA
GYPEKHFEAPNIQSDLYYLKKKVEAGAEYIVTQMFYDNQKYFDFVDLCRKNGINVPIMPG
IKPISIARHLNILPSIFNIDIPEALAIEVRKCKTNKDVRQVGVEWAIEQSKELIKHNVPS
VHYYTMGKADNIFNIAKAVF
>A0A1L2A8U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylella fastidiosa|TrEMBL
MIPISFEFYPPKNDDQRAQLDRTANRLRTFTPEYVSCTFGAGGSTLSYTSETVRHLSQHH
GFDAAPHLSCVGGSRQEIRELLKLYRAIGCQRIVALRGDLPSGMGHPGDLRYAADLITFI
RAEHGDHFHLEIGAYPETHPQASNTLNDLHYFKAKADAGADAAITQYFYNPDAYFHFVDA
VQRLGVTIPIVAGVMPISNFDKLHHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVV
TALCERLIAGGAPGLHFYTLNLAKPSTQVLQRLGY
>N9MPH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4105|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKLVHQELQLLNPEFFSITYGAGGSTRERTLAAISDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDSDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERITKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A3D8IBD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. MIT 14-3879|TrEMBL
MDNKIKSILQKITKNESFLSYEVVPQKSFSLNKTLESIKKSKLNEIFDCYICTDSPLARL
KHSSILASIKIQNYLNKPTICTISTRDKNSIALQGEIMGLNEFNIRIFLALSGDPIKLGD
QPQAKAVFESNSCIIFDIINNLNQNKDLQNKSLIDSGKKIYHLGVINSYANNMENIYKKM
YKKIQKGAIALITQPVYSIDNIKELLYMIDKINKELKVQTSIIFGYYPISSLKTALFLYN
KLPGCYIPDIWINELKSAGDNEERVGIELSKNLYKEINNIYPKIHFMCANKISLAESILL
N
>A0A511BQ00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Swaminathania salitolerans|TrEMBL
MSRIAIELVPRDAATLERDLETVRTLLPGIGTINIPDLLRLDLRSWEGGAIARDRGFAAI
PHIRAVDIDPDLPLPCAGQEGIGEILVIAGDPPPDSTHRVFPNTSADIIARYRREAPHLA
VYAAFDPYRRAPWQELEDIQRKRDAGAAGFFTQPLFDRRMFELSASWLEKDTVFWGISPV
IGPKARAYWERVNHVVFPRDFDPGLEANIAFAAMMLREIRARNENAYLMPLRVDLEAYLA
PLRDVLSP
>A0A1I4IJJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia sp. CL147|TrEMBL
MSCTDVRYSFELYPPRSERAAASLPATIDRLAATHPDFISVTYGAGGSSRSASLEVLRYI
IDNTDVSPMAHLTCVGSSHEEANRLIREFLDAGVRRFLAVRGDPPAGLPEGDDGIGDIRT
TAELVQLIHRVQAERSPYGELVVPELRAQAVLQHREHVQIAVAAFPNGHPSSHSVSQDID
ALLAKQAAGANLGITQLFFHAEDYLHFAQRAAEAGVAFPILPGIMPVTSPARLKRMLELS
GEDLPSDLAIELEVEPTDEGRREIGVAWAARLGERLLAGGAPGLHLYTFNQHEAVLSVLD
RIGALPSSDHRDSTLPEKSATEKEPA
>K1SVH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|human gut metagenome|TrEMBL
MNITDLIQGAVASRTTRFAFELLPPLKGDGTRSVFGAIDPLMDFNPAYINVTFHREALKE
DIRPDRKPSSGTSCAAVRARSALSAAIRRKYDVEVGS
>A0A7U8QNC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. D20|TrEMBL
MQDFCQSDKDNEREMRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYI
NITTHRSEYVYKDLGNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETE
YVLLDLQFLGITDLLVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMK
VTNTPFSYGVACYPEKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERAR
QAGVTIPIIPGIKPFKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQ
CKELIAHGVPSLHFYSVGATDSIKEVAKQIY
>A0A6M9PF48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter asymbioticus|TrEMBL
MELSVEFFPPKTPEGENKLHLVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
AETGDWFHIDVAAYPECHPQAKSPASDIHFFVEKMKAGANSAVTQYFYNSDAYFRFVDEA
YNLGVTQPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDSASIRAFGEQVVT
DLCDQLLVAGAPGLHFYSLNQADAVLAIADNLSLNK
>A0A7Z0P2N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SbOxS1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLSQYKAAGIQRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDINNFVRKANAGADSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1Y0RT93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostocales cyanobacterium HT-58-2|TrEMBL
MLDTINPTALTSFRTAAKSGQFLITAEVTPPKGGNPDHMIKMAATLKGRVHAVNITDGSR
AVLRMSSVVASAILLQNGIEPICQLACRDRNRIGLQADLMGAHALGIHNILALTGDPVKA
GDHPEAKGVFDLESVRLLQLIHKLNHGVDCNEQPLSDGALDLFPGAAVDPQCSSWSGLQS
RFERKLEAGAQFFQSQLITDFERLEKFMDNIAIGCKKPILAGIFLLKSAKNAQFINRCVP
GVNIPQHIIDRLAQAKDPLEEGIKIAAEQVQIARQLCHGVHMMAVKREDLIPQILDIAGV
ASLS
>A0A4R0FYY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter wuhouensis|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPHWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1S7HH24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygosaccharomyces parabailii|TrEMBL
MSIRELYDVKEGPTLSLEFFPPKTEAGKQNLLDRMERMSALDPLFITVTWGAGGTTAEKT
LELASLAQKNLNLPVCMHLTCTNMDKHIIDDALMKCQKSGIRNILALRGDPPIGQDWSDL
EAANSEFKHAVDLVRYIKTHHPGEFCVGVAAYPEGHCEGEAEGYEQDPLKDLPYLREKID
AGADFVITQLFYDVEKFLSFEVLFREQVSSEIPLIPGLMPINSFLLFNRAAKLSHASIPQ
SILRKFPPEVQSDDDTVKSIGIEVLIDIIERIYKSTSGRIKCFHFYTLNLEKAVAKIVAN
SPTLCNTLEEGEDENEEAATSEPEQDKEGDIVLEDAIGVNVKNLINESRKRRRQSSNVSN
ISSELTSNRVIIGQRNQQGVGAPSRKVVVSISQGSGTLGQNATWDEFPNGRFGDSRSPAF
GEIDGYGPTIKVGNKKAYELWGSPQKIKDLQTIFIKYLEGSIDSLPWCDLGLSAETALIQ
EELIQLNDRGLLTLASQPATNGSCSTDKIFGWGPANGVVYQKAFVEMFVPRYMWENGGMK
RKLEQYGHAKLTYYATDSRGNFETNLKPNSSNVVTWGVFSDSQVVQSTIVSEESFKAWSD
EAFSIWLEWAKLFPRNTPTNSLLRQVHQEYCLASIVHHDYINPDELWEILLA
>A0A419WA15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mangrovibacterium diazotrophicum|TrEMBL
MKVIDIINQSDKTVFSFELLPPLKGNDASNIYRTIESLIDYNPKYINITTHRDEMIYKEM
PDGTIVKQVVRKRPGTVAIAAAIQHKFGIPVVPHILCGGFTKSETEHVLIDLHFMGIENV
LALRGDGLKSDSVFRPDPNGHGNADELVKQIVDLGKGKYLDPDLKNSTPLEFCIGVAGYP
EKHFEAPNFDTDLAYLKQKVDAGAEYIVTQMFFDNQVYFDFVKKCREAGINVPVIPGIKP
ISNLNHLTILPKIFSIDMPQDLVNELKKCKNNADAKLVGTEWAIQQSKELVANKVPSLHL
YTMGMSDNARKIVEAVF
>A0A229RS94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis thailandensis|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPDGLDYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGVMPLTTLRTLHTSIKLSGAPAPRRLLDKLEPLA
DDPKAFRAAGIDTVTEMCERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A6TGD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A2D5HM31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MLTENPVNIIKNVAKNWSIEITPNAANKIDDFSKILKEKTIVNVTFLPNTNLLETIEVSR
RLYESGMTPVPHISARAIRNTDELDYFVKSLTQSCGVNEVLVIAGSSSSPADKFNETMQI
LNSGILEKYNIQKVGVAGHPEGSPDISDELINESLKRKYEWSLKTGIPIYIETQFLFEAE
PVLDWEKNIRDQGMKIPVRIGVPGPATIKTLFQFAKSSGIGPSMRMITKQAKNISKLFIV
QAPDKYIYDLAFGVYNDKECTIEHLHFYPFGGFKKTALWATXLEKGEFSLNDKGGFKIHE
N
>A0A165UBS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neolentinus lepideus HHB14362 ss-1|TrEMBL
MKISKKIEQAQKENKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
DLTSELVKTCQKIIGIETCMHLTCTNMPQEKVDIALREAKQHGCRNILALRGDPPVGKDE
WEAVEGGFVHGIDLVRHIRKEYGDYFGIAVAGFPQHVRLPPEELEFELKCLKDKIDVGVD
FIMTQMFYDVDIFIDWVKAVRAYGITIPIVPGINPIQTWNGFMKSTALARTTIPQSLLDI
LEPQKHNDEKVREIGTKVVADMCRRILAEDIGIRGFHFYTMNLEKATRMLLEELQLVPRV
ETIKPLPWRQSLTPTRRNETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIFINKTKEEAYKLWDHPATYKEVSLLFAKFCRGNLAALPWSDSPPSPETSVIADKLA
KLNELGFLTINSQPAVNGVRSDDRRFGWGPSNGYVYQKAYLEFFVSPELLALLLPHIERD
PNITYHVINKSGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGYQ
WARLYEPDTPTRKVIADIMNTHYLMNVVHNDFQSADDIFEPFFKAGEQLAASK
>A0A7Z9YYS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MLVKDLLESHKTTFSFEFFPPKKDAAADRLLQTISNLMPLGPSYVSVTYGAGGTTRDRTH
DLVLRIREQTNITVVSHLTCVGSTREEIHTILEQYQDAGVQNILALRGDPPAGEEDFVQP
KDGFTYAADLVSYIKKHFPEMCVGVAGFPEGHPDTPNRLQEIDYLKAKVDAGADYIVTQL
FFDNRDFYDYCERCELAGIHVPNIAGIMPVSTKSGLIRTAELAGGARIPARLLKAAYRAE
NDEYVEKVGIHWATEQIRDLIDNDVRGVQFFTLNSSEATLEIYNSLGVRDSTQLR
>A0A098ENS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus massiliensis|TrEMBL
MGLLEELKTRILTADGAMGTLLYSYGIEYCNEELNLQRPDIIEKIHEEYIQAGADIIQTN
TYGGNALKLARYGLEHQVKEINEAAIEIAKRAAAPGGQFVFGTIGGIRGIRRSDAALDEI
IAMVDQQSGYLLAGNPDALLLETYYDFEELAATVTHLRKRTDVPLIAQVSMHEPGILQNG
MALNEALHQLEGLGADIVGVNCRLGPHHTIQALEGVELPKKAFLSAYPNASLLDLENGRV
VYESEADYFGRAGLLLREEGARLIGGCCGTTPKHIEALKKQIGHLEPITVKEVETKKPIV
IREAELSNEVPLHEKAKTERTIIVELDTPKHLDTTKFLEGSKALNAAGVDAVTMADNSLA
SPRVSNLAMGSILKHQEQIRPLAHITCRDRNLIGLQSHLMGLDALGIRDILAITGDPTKV
GDFPGATSVYDVSSLELIQLIKKLNDGISFSGKPLQKKASFSVAAAFNPNVRVLDRAVAR
LEKKIESGADYFISQPVYTKEKIIEIHKATKHLETPVFLGVMPLTSIRSAEFLHNEVPGI
KLSEEALERMRACGEDKERATAEGIQIAKELIDTAADLFNGIYVITPFFRYDMSIELIHY
IRKLDQQKESDHSHVQTAN
>A0A7Z9XFC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MAKSFEEALTSGKFLVAASLDPPKGTDLGHSAKLVKELKRVVDALGVSDNPCAVMHMSPW
AVCRLALEQGVEPIMHVTCRDRNRLALQSDLLAAASIGIKNILCVSGDHVKFGDHPDAKP
SHDIDSVHLLGVARAMAEGKDMVGNPLTGSPAFCLGATANPEADPLEPQLIKVDKKIQAG
ASFLVTHPVFNMENLKRLMERVRHSNIKVLAGVRLLVPEDVPKYRDGAYPGLFVPEEVLE
EIDGADTAACVEIAGRLLKDIKSANLCDGVHITAPRHEEIILDLF
>I3QGA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blattabacterium sp.|TrEMBL
MKVTEHIDKAKKSLFSFEILPPLRGRDIKDIFSTLDPLMEFCPPFIDVTYHREEFIYVEK
DNGLLQRRKISRRPGTVGICAAIMNKYGIDAVPHLICGGFSKQMTENALIDLNFLGIDNV
LVLRGDPLKSENSFFAQKDGHKYAAELVKQVKNLNIGKYLDKTFVEKKKSTLFDFCIGVA
GYPEKHLEAPNIESDLFFLKKKVEAGADYIVTQMFFDNKKFFSFVKKCRLEGISVPIIPG
LKPISSKKQLNGLPSRFNLNIPNELVKEVEKEKDKKNVFHIGIEWAIHQSKELKNSGVEV
IHYYTMDRPENIYKIVQAVY
>A0A7W3WDZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. G21|TrEMBL
MTKYCRDIALSFEFFPPKNADAARQLWDTVDDLKKWQPEFVSVTYGAGGTTRDTTLDTVS
TILGEHGLDAASHLTCVGSSRDEVRQVVADLKRAGVRRIVALRGDPQGGFGQAYAPHPEG
YAYASDLVAGLIDIGGLDISVSAYPERHPESADWAAEIDNLKRKADAGADRALTQFFFDN
DLYESYVDKALAAGVTIPIVPGILPIQNLAQVQRFAGLCGASVPDFVVQTLGPVEDHAEE
RFRRAAELAATQVLDLIRRGVDQFHIYTMNRSALTSEALRLSGFEPARFEMPALTIAA
>A0A7Y2ZYK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKVKTPSKLEKVLAAGHLAVTSECGPPRGSDPEPIIKKAEMIKDHVDAINITDNQTSVTR
MCSLAACIRLKLMGLEPVLQMVTRDRNRIALQSDILGAASFDINNILCLSGDHQSFGDCA
QGQNVHDVDSMQLIQTVRHMRDESKFLGGDDIARPPQMFVGAAANPFADPFEIRVPRLAK
KVAAGAEFIQTQCIYNLDKFEEWMKLVVDRGLDEKISILAGMTPMKSAGMAKYMKNRVPG
MDVPDEIVKRLADTPKEKQAEEGINICVEAIQRIKEMKGIKGFHVMAIEWEEKVPEIVER
AGLHPRPDLN
>A0A7Y3ADU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
GKLSSVLDHLKQGHTVEGDELAQKAEFVLGSGVESSWGKNVPELEMKEMEEMTKIGTGYF
LTTPVFNLDQFEKFIKNVDTLGVPIIAEVLIIRTAGMGQFLNRHMKPGLVPDWVIKKLAR
APDKQKASIEIFADIVSGLKDICQGVHIISIGGEQRLRHYLDAAKLK
>A0A7C0UBD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
KNVAGVNVPQSLKDVMASAPKGKDIDKGIEIAGRMVRHICEEKMCHGVHIMAIGREELVP
EIMAAAGLL
>A0A8B5EBA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. CH278|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A1J9RBN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diplodia corticola|TrEMBL
MEKITDKLAALPPDGRYFSLEFFPPKTQMGFANLQNRLERMASALRPLFVTVTWGAGGST
ASKSLELAELTQRQLGLTTCLHLTCTNMSRSLVDDALEQAKALGVRNILALRGDPPRSEE
YREGHAGTDNDSNKDFTWAVDLVRYIRSKYDDYFCIGVAAYPEGHSDQSHPDKQDPKFDL
PYLIEKTKAGADFIMTQLFFDIKAYEEFETMLRNDPSGVFKTMPIIPGLMPIQSYQILRR
TTKLSHAKLPPALLERLDAVKGDDEAVKSVGVDILSEVVEELKARPNPGPRGFHFYTLNL
EKAVAHIVERCHLITAISPGGDDEEAVTIDDIPVNGGAPSDSLKVKNRRRLSSANSTPHN
RVVVDRPSTSSNKSYEALADEVGVPKDKIMTRANTLAISEGEGTLGREATWDDFPNGRWG
DARSPAFGEIDGYGVSLHVSIPQAIKLWKYPTTVEDISDIFRRHIMGDLEAIPWSEEGLN
EETETIRDQLLKLIAKGWWSVASQPAVNGIKSTDAIFGWGPKNGYVFQKPFVEFFLSSAD
WTKLQAKLDELSDVTYFAGNHAGEYSSNDEDSVNPVTWGSFAGKEIVTPTIIESVSFRAW
LEEAFSIWSEWRHIYPPRSATANLLGHIRDDYWLVNIIHHDYVEQDALWRLLLAE
>A0A5C7XNG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp|TrEMBL
MTAVSFEFYPPKTDEQRAQLDRTAAKLKSHGPDYVSCTFGAGGSTLSYTSETVRHLKQEH
GLEAAPHLSCMGGSREEIRELLRLYRALGCKRIVALRGDLPSGMARMGDLRYGSDLVAFI
RAEHGDFFKIEVGCYPETHPQAEDALADLRHFKTKMDAGADAAITQYFYNADAYFRFVDD
ARKLGVDAPIVPGIMPISNFSQLKRFSDACGAEIPRWVAKRMQAFGDDADAIREFAADMV
AAMCARLIAGGAPGLHFYTLNLAKPTQSVLSRLG
>A0A0H2R8G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schizopora paradoxa|TrEMBL
MKISDKIAQADKQDRIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQSLIGIETCMHLTCTNMPKEKVDIALREAKAHGCRNILALRGDPPLGKDD
WEAVEGGFIHGIDLVKHIRNLYGDYFDIAIAGFPQNMLLPPDELALEMKYLKEKVDAGCN
FIFTQMFYDVEIFIKWVHEVRRNGITIPIVPGIAPVQTWNGFMRATSLARTVIPQDWLDQ
LEPNKSNDEKVREIGLNLVANMCRRILKENLGIRGFHFYTMNLEKATKMLLEELNLVPRV
ETIKPLPWRQSLTPNRRSETIRPIFWANRTRSYIARTENWDEYPNGRFGDSRSPAFGELD
GYGVWIKQTQEEGLSLWGHPTSFAEVAKLFSRFCLSDLAALPWSDEKPSAEMKVIGAQLA
KMNELGFLTINSQPAVNGARSDDKAHGWGPANGYVYQKAYLEFFVQPDLLAALLPLIERD
GNVTYYAINKRGDLRTNTHSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELGNQ
WARFYEPDSPSRTLIKDLMETSFLVNVVHNDFKDPHAIFKPFIQAGENYAAQKSTPNGTT
VNGVNGVH
>A0A7L9GLH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas taiwanensis|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQVARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQASPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALETRIEHWQSQVQSLEQWTPA
WHASWQMPGLPAVTFHPPQACWRLGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPLWATRAGAHVLHTLERNVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A840QBS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora phatthalungensis|TrEMBL
MTRVIDRLRPGRTVFSVEFFPPKSDEEERQLWRAIRELEPLDPAYVSVTYGAGGSSRDRT
VRTTGRIASDTTLLPVAHLTGVNHSIAELRHVIGSYAAEGISNVLAIRGDPPGDPMGEWT
PHPEGITYADELVRLVRECGDFSVGVAAFPHMHPRSVDLESDTVHMVNKLRSGADFSVAQ
MFLQPEYFLRLRDRLAQRGCHQPMLPGIMPITTPRVLGMTTQLSNMTIPDEVSAVLDPLR
EDAAGFRAAGLEITTRLCEKLIAEGVPALHFYSLNRAKATREVVANLGLSDGVLKAA
>A0A8K1MTH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phormidium sp. PBR-2020|TrEMBL
MSRLRSAIQAGEFLITAEVAPPKGGDPTHMLKMATCLKRRVHAVNITDGSRAVLRMSSLA
ASALLVQYGIEPVFQVACRDRNRIGLQADLMGAYALGIRNVLALTGDPVKAGDHEQAKSV
FDLESVRLLQTLNKMNRGLDFNDRPLSDGKLDLFAGAAVDPQLASWSGLQRRFERKIAAG
AEFFQSQLISDFDRLEKFMSQIAARYDKPILAGIFLLKSAKNAKFINKYVPGVHIGEDTI
DRLDEAADPLREGMAIAAEQIQQAQQLCQGVHLMAIRTEHLIPEILDMAGIPPISRPSSL
AR
>A0A7X7TBI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MTRRLRQSLENLAHFTVVAELTGGPGYDFRPIGKFLTDYRAAGTDAIPAGFDFVGVAVPQ
NPGGVANLEPTDILAKIDSAGLLGDLDFIPHISCKDSNADGILSSLVGYRTRGIETVLAL
TGDRPVSAKGVFELESVTLLKMIRRLNHESILKGQPGQWDRVHRFFAGAAVSSFKYTEPS
LMQQYYKMEKKIAAGAGFVITQVGWDWKKSLELMRYIRRRGIDVPLVGNVYLLTTTNPAP
RLMHDGKLPGCYVSDELLARLRQESYDQHLDRAAQQIAMYRGLGYSGVDVGGTHDFSTFQ
EILRRAAKIGAEWDAYKDNLCFTPAHAFYLYSTTGEEAMLSSSSKTTGQRFFSFMHRAIL
DPSHRGFHWFRGAMKHTHASKGRGFVYRTFNAAEKAAKSLLFECESCGDCLLPEHCGVCT
IGPCAKGLPNVPCGDATVEGKCGNDLELVCVGERVYQAAAAEVGGREKLRKLVNPPRNPA
LEGTSSVLNYLFGKDHTMPNAIISIGEAIHASIPKTGKVMKELHELGPDAYTKDSGPLRY
VRALIESQADEKADYLAVNLDAFGESDSSQTVRMMREYTRLVRRWGGGVPICFDSSNDEA
LVAGLEEWYSTGEPVKTPLINSIKVYSMDKMFPLKSRFEYNFIGLLVSEGKPQGPGGSHS
VEELYGIAKQIFQKATGQYGFKPEQIFFDSTVFPLAIDMPMEPGVPGYTYRAFETIRRIK
SDPAMKGVHCSLGVSNCCRDLPGRKVGVCRAYVAKAMEYGLDAGIVNTSHQYGQKPADPE
LLDLVTAFAKLDGTMDRLNDAMMKMGQFCADNRKG
>Q72DD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough)|TrEMBL
MKIAEAIERQSRPFYSLEFFPPKEREQWPAFFATVERLKAMDPVFASVTYGAGGGTQDNT
LDITAHLKNALGLEPMAHLTCVGATRERIAGFLARLREQGVENVLALRGDPPRGQQVDWE
TAEFRYASDLVRFVRNEFPEFGIGVAGYPAAHPESVSFSQDIAHTCQKIHAGADFVVTQL
FFDVREYFAFIERLKECGVEKPVLPGILPIQSLESIKRILALCGANIPGKLYLELEEADA
RGGAEAVREAGIAFAVRQIRSLIDGGAPGIHLYTLNKADMCLQIRDAVGAL
>A0A7W3NAQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia aryabhattai|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINVAGVKLAKQAAKDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLSEGVDGLLFETYYDFEELKTVLTLARKETDKPIITHVSLHDIGVLQDGR
PLADALKELEALGADVVGLNCRLGPYHMIQSLEEVPLPDRAFFSAYPNASLPAYVEGKLE
YETNEDYFVESARLFREQGVRLIGGCCGTTPAHVRAMSSALKDLPPITSKVVKMRPAVTV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRIRGEVEGLAIAKNLIDTAYELFDGIYLITPFMRYEMTEILTRYI
HDKQLVTSERKI
>A0A3Q0RQN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amphilophus citrinellus|TrEMBL
MVNQVQRGDATWQPCKSDSSGASNSGGESSKESSRCSTPVLDAYRSDRLRDKMRRRMESG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNLSKEKITGYLAKAKHLGLKNIMALRGDPVGETWEEEEEGFSYAI
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGADFVITQLFFRPDTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRN
YGIQQAVEMCRVLLDSGKVPGLHFYTLNREVAPMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLQMWGEELQNEESVFEVFTCYITAQPNRCGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPVVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVQGRNLTNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWG
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWQVIDDMFELLDSPPEPHGEETV
>A0A5T0NI62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKKELHV
>A0A1S2C7Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia aryabhattai|TrEMBL
MGLLEDLKSKILIGDGATGTLLYSHGIDSCFEELNITKPEEVSRIHRAYVEAGANVIQTN
TYAANYQKLARYGLEDSVKDINVAGVKLAKQAAKDQAYVVGTLGGIRSFQKNAISLEEVK
RSIREQMFWLLNEGVDGLLFETYYDFEELKTVLTLARKETDKPIITHVSLHDIGVLQDGR
PLADALKELEELGADVVGLNCRLGPYHMIQSLEEVPLPDRAFLSAYPNASLPAYVEGKLE
YETNEDYFVESARLFREQGVRLIGGCCGTTPAHVRAMSSALKDLPPITSKVVKMRPAVTV
QEREQQDKPHMHEIVKKRRSVIVELDPPKQLGPTKFLEGAKALDKVGVDAITLADNSLAS
PRISNLAMATLMQQETKARPLIHITCRDRNLIGLQSHLMGLHTLGMNQVLAITGDPSKVG
DFPGATSVYDLSSFDLISLIAQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDRAVQRL
EKKIDCGAHYFITQPLYSTKQIEEVYEATKHLTTPVYIGIMPLTSARNARFIHHEVPGIK
LSEDILERMDATGNDRIRGEVEGLAIAKNLIDTAYELFDGIYLITPFMRYEMTEILTRYI
HDKQLVTSERKI
>A0A2M9C121|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium geocarposphaerae|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVHQINDLGRGKYLHNQDEVCDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVTKAREMGITVPIIPGI
KPIATKKHLKVLPQIFKIDLPEELINEVEKAKNNESVKQIGIEWAINQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A2E5E4A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MHIRDILERDKTTLSFEFFPPRSDKAAASLADRLGAFESLEPSFVSVTYGAGGSTRQRTH
DLVVSLKSSGKLDPVPHLTCVMQKPDELDEILARYAAHEISNILVIRGDAPEDAQGYDPA
AEAYPHAVDLVKTIRAFNDAGRHADPRGFGIGVAGFPEGHPETPNRLRQMDHLKAKTDAG
ADWITTQMFFDNRVFYDWCEQCEIQKIDIPKIAGIMPITSLATMKRMADLAAGTNFPAKL
QRRIHRYQDDDHAVEQVGVQWASEQCNDLLDHGVRGIHFYTLNRSDATQRIFEALGASSG
LPSIRT
>A0A1Y0KM85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. M30-35|TrEMBL
MSQERRFSFEFFPTKTEAGHEKLMATARQLATYNPDFFSCTYGAGGSTRDRTVNTVLQLD
GEIKVSTAPHLSCVGDSKAELRELLDLYKSNGIKRIVALRGDLPSGMGMASGELRYANEL
VAFIREQSGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADSYFY
FVERVRKMGVEIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIDSIQAFG
QQVITEMCEQLLQGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A1B1ZPI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. HH130630-07|TrEMBL
MASAPIAPAAELLARARDGVLLYGLTPPRQSSTREQADSIAAAALTRLESVHVDGLILYD
VDAEADRTEAPRPFPFMPMMDPADFLDHHLAGWAGSVIVYRAVGKYGADQLDQWLGEADQ
GRVLTVLVGAASRHQMVRTSLPEAYRRHAALPRPPRMGGVVIAERHAEAGTEHLRMLRKQ
EAGCEFFVSQICYDLNRTCNLLSDYAHNCRDQGLDPRPVVLTLAPCGSAKTLEFMTWLGI
EVPRWLRAEINRGDPLAASYEHCLLNARALIAFCRRLGLPFGINVETVTNRKVEIDASID
LVREVRDLLG
>A0A4R8XPS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMS1-20-1|TrEMBL
MSACNARPAFSFEVYPPKSAAAASALMSTIDHLAAAGPEFISVTYGANGSSRNSSLDVLR
YIKNHTEADAMAHLTCVGSSHAEASRLIREFLDAGIRSFLAIRGDAPPGAVEGDNTFLGD
LHSAGELVQLIHRVQTERVPYIETVIPGLPGARGVKTERSKVRIGVAAFPNGHPNSRSVS
QDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLFPILPGIMPVTSPNRLRRI
LQLSGEKLPAGLSIDLEVEPTEEGQRQIGIDYAVRLGQDVLAGGAPGLHLYAFNQHDTVL
QVLEGCGALPVPAVML
>B9Z0I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogulbenkiania ferrooxidans 2002|TrEMBL
MSIPFSLELYPPTSPQSARQLERALPRLAALGPEYFSVTYGAGGCTRERTLDLVGQLHEA
GHTVAPHLSGVGAERAEVAELCAHYRRLGVRRLFALRGDTPSGMGSRGDFAYASDLVRFI
REHSGDDFRIEVAAYPEVHPQAKSPAADLAALRVKQEAGANAAVTQYFFNTDAFLYLRDS
CHAAGITLPLVPGVLPLTRFRSTAQRAEARGIEMPRWIYRKMESLADDTAAVRAFGLDVT
ARQCERLIAEGVPALHFFSLNQIDAIEALHARLGLAGSAGTTAAPPN
>A0A240UF47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax carolinensis|TrEMBL
MTAANAPATGLPVSFEFFPPKTPEGAGKLRAVRQQLYALQPEFCSVTYGAGGSTQEGTFG
TVQEILAEGVSAASHFSCIGATRQSVREELATLKTMGVKRLVALRGDLPSGYGIGGEFHY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQAKSADADLQAFAAKVRAGADSAITQYFFNAD
AYERFVDDVRRMGLDVPVVPGIMPIMGSSQLMRFSDACGAEIPRWIRLRLQGFGDDMASI
RAFGLDVVTSLCEQLRQRGVPGLHFYTMNQSATTLELCRRLGL
>A0A1Z4QDI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cylindrospermum sp. NIES-4074|TrEMBL
MPPDTHSTPVLNTFRSAALAGEFLVTAEVAPPKGGDPTHMMKMAATLKGRVHAVNITDGS
RAVLRMSSLVASAILLQNGIEPVCQMACRDRNRIGLQADLMGAHALGIRNILALTGDPVK
AGDHPEAKPVFDLEAVRLLQLIRKMNQGVDSNDKPLTDGTLDLFAGAAVDPQSKSWSGLQ
SRFERKIEAGAQFFQSQLITDFELLEKFMDKIAASYKVPILAGIFLLKSAKNAQFINKAV
PGVNIPQHIIDRLAKAKDPLEEGMQIAAEQVQIARQLCQGVHMMAVKREDLISPILDLAG
VEKIS
>A0A2T5GB52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brockia lithotrophica|TrEMBL
MAFRILVEVPPPKSNVVGPFLANVEALSAMDVDAVTLSDNSLAQARMANVVAAQLVRQKV
GLPVVLHVNTRDRNLLAQQSLFFGLAALGIQDVLIISGDAMRLGDHPEGKTVYERTSIDL
MHLVRGMNEGRSFFGRPLKNPTSFRIGGALNPTSAGGFSRERALRKVEAGATFFLTQPLF
SDRMLEALDDLRSFLPAGIELYPGFMPLVSEKNARFMASVPGFSVPDSLLRAYAERPEDP
EIGVEFLLDLFERNKSLLSSFAGVYLVTPGRKADILRPLVEYLRRQFARK
>A0A8C7R2E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
MVNNVQRVDDTWRTCTKSNSSGTSNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSNKETSSMMIAST
AVNYCGLESILHLTCCNQTKEKITGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYA
TDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADT
FLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIR
NYGIEQTVGMCRVLLESGNVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHP
KRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKD
ALLKMWGEELTSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDELLAPETNLMMDELDKVN
RRGVLTINSQPTINGKPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPR
VNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQW
AKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPTDGI
A
>A0A1R1PIX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zancudomyces culisetae|TrEMBL
MVELCGIEVPKRVMEELAAIKDDDLQVKDYGIKYGVEMVREILEFGDEQLGLIQTKRDTN
NKQQDICCEETKTLPWPMGSIREGELVRPIFWNNNQQSYIQRTNSWDEFPNGRWGDFRSP
AYGELVHGMNWR
>A0A847PLK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MSILKKTFDAGKFAVTAEMAPPKGVDFSHQLEDAKLLKGKVHGINVTDMQSACLKASSIG
LCAALKNEGLNPIIQMTGRDRSRMAIMGDLFAAYALGIDTMLALTGDHTTVGDCKDSKPV
FDLDSCGILKMLSDMEATNTDCGGNALDGPTPVFYKGACVTPMYEPQILQIAKLKKKVDA
GAEYIQTQGIFDIDALKRFMEAVEKANIKVHIMAGIIPLKSAGMAKFMNANVPGIEVPDS
MIQRLSDAAAEGKEKDIKGLPEKAGIEMAVDMIRQIKDEGLCDGVHVMAIGAEKNVPIIL
DMAGVSI
>A0A8C3AHV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclopterus lumpus|TrEMBL
LVKLNSTKTGLSNSGGESSKESSRCSTPVLEADRSDRLRDKMRRRTESGDRWFSLEFFPP
RTASGAVNLISRFDRMSAGGPLFIDITWHPAGDPGSDKETSSMMIASTAINYCGLESILH
LTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEEGFNYATDLVKHIRSEFE
DYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTFLKFLDDCRAIG
ITCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITRVIEPIKDNDAAIRNYGVQQAVEMCR
VLLDSGKVPGLHFYTLNREVAIMEVLRQLGLWIEDPRRSLPWAVSAHPKRKVEDVRPIFW
ASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSTKDALLQMWGAELMN
EESVYEVFTCYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNKRGVLTINSQPN
INGKPSADPIAGWGPAGGYVFQKAYLEFFTSSENVTALLEVLKKYEPRVNYHIVNVHGRN
LTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWAKLYEDESPSRM
IIKYIHDNYFLVNLVDNDFPLESCLWQVIDDMFKMTDLTDEQPMRQKQNF
>A0A6P2FFT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. PBL-E5|TrEMBL
MPFMRTANQEPAVRLPLSFEFFPTKTPEGAVKLRAVRQQLYAQKPEFCSVTYGAGGSTHA
GTFGIVGEILAEGVDAASHFSCIGATRETVRAQLAELKAMGVRRLVALRGDLPSGYGIGG
EFLYASDLVRFIREETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVHAGADSAITQYF
FSAEAYFRFVDDVRKLGLAVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDD
TASIRAFGLDVVAALCERLCAGGAPALHFYTMNQSVATLGVLQRLGWSE
>A0A089XIM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces glaucescens|TrEMBL
MNPGPTAPRATHTALLEDFSLEMTGKDVPHLEEAHHLVPPGTRINVTFLGNEDLRMRLAA
ARAVKRLGFVPVPHLSARRLASRAELEEFLEGLRADGTGEHVFVVGGDPARPHGPYEDAL
AVIRTGLLERYGVRHVGVSGYPEGHPAIAGPVLWTALADKTAALARRRLGGHVITQFGFD
AGPVLSWVAETRGRGIDLPVRIGVPGPAGVRRLVSYATRFGVGTSASIARKYGFSLTNLM
ATAGPDRFLRDLAAGYDPAVHGDLRVHFYTFGGLRATAEWVAGFAARPAAESGAGA
>A0A3C0CIN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKLIQIISQKKPSLSFEVFPPKNNGRYENLRSAIARIAELSPSYMSVTYGSGGGTSSTTV
SIAAALQKSYHVPVLAHLSCIQSTREGVRSQLDALRAAGIENILALRGDLPPGSEPQAGW
YYRFASELVREIRRYGGFCVGGACYPEGHPESRTQMEDIAHLKEKVEAGCDFLTTQMFFD
NNIYYNFVYKLREAGISVPVVAGIMPVTNLKQIRRILALTGTALPQRFRYILDRFGDNPA
AMKQAGIAYATGQIVDLFANGVPAVHVYSMNNPSVAGKIRQNLSEILK
>A0A1H0DLP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces guanduensis|TrEMBL
MAMGTPSTRTDRALTIRELLAGGGRSYSFEFAAPRTEKGERTLWQAIRRIEAVQPTFVSV
TYGAGGSSREGTVRATDRIVSDTTLTPCAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVRLIKESGDFCVGVAAFTEMHPRSTDPAEDTRHFID
KCRAGADFAITQMFFDADAYLRLRDRVDAAGCPVPIIPEVMPVTNVRQIERFSQLGNAPF
PPALAERILAVQDDPAAVRAIGIEFTTEMCRRLMAEDIPGLHFITLNHSTASLEIYENLG
LHQRAA
>A0A3G4V8T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio mediterranei|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSTPTMEETLWKSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSETGLVAAPHLTCIDASRDELIDIAEDYWSNGIKNIVALRGD
IPAGGGQPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAGMNKVKVPGWMQKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPPSLVIS
>A0A238D5H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomonas delicata|TrEMBL
MDIPNLSFEFFPPKTPEGAVKLRAARQQLYAHRPQFCSVTFGAGGSTQDGTLHTVKEIAE
EGVAAAPHLSCIGASADSIRNLLRRYRAEGIRRIVALRGDLPSGYGIGGEFHHARDLVAF
IRAETGDWFHIEVAAYPETHPQARTPQDDLRHFAEKMRAGANSAITQYFFNSDAYFRFVD
EAAAIGVDAPVVPGIMPITNASQLLRFSEVCGAEVPRWIRLRLQSFGDDRASILAFGREV
VADLCDQLLAGGAPGLHVYTLNQAAPTLDLLRDLGGR
>A0A1G8LJZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutimaribacter saemankumensis|TrEMBL
MRTPDISFEFFPPQTLEASFRLWDTVNVLAPLAPRFVSVTYGAGGTTRDLTRDAVATLHK
TSGLNVAAHLTCVNASKAETLEIANGFAEAGVREIVALRGDPPKGSDGFRPHAEGFANSV
ELIQALADTGKFNIRVGAYPEKHPESPDAQADVEWLKRKLDAGADEALTQFFFESETFFR
FRDACQKAGIDGDRITPGILPIENWKGARKFALSCGTSVPAWLDDAFDKAIRDDRSDLLA
TALCTEMCSELIEGGVKRLHFYTLNRPELTRDVCHALGVTPRVQLENVA
>A0A2S6UIK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha4_Bin1|TrEMBL
MTTVPSVSFEFFPPRDDAGEERLWKTAERLAPLAPSFVSVTYGAGGSTRVRTDRVVRRLQ
ADTGIDVAAHLTCVGASKEEVDAVAARWWKAGIRQIVALRGDMPGIAEPYRPHREGYANA
ADLVAGLRGIADFDIAVAAYPEIHPDSENLAADLDNLKRKIDAGATRAITQFFFFTDLFL
RFRDRAAAAGITVPIIPGILPVTNFAKVQEFSARCGAAVPGWMAELFDGLDNDPETRKFV
AVSVADDQCRRMLAEGVENFHFYTLNRADLSYAICWRLGLRPLKKEA
>A0A0U2WJD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pandoraea norimbergensis|TrEMBL
MTQPSFSFEFFPPKTAEGAEKLRATRQQLFPLGPKFVSVTFGAGGSTQQGTIDTVVEIQR
EGVEAAPHLSCVGSTKDNIRDILQTYRSHGIRHIVALRGDLPSGMGEIGEFRYASELVEF
IRAETGDWFHIEVAAYPEYHPQAKSPRLDLEHFADKVKAGADSAITQYFFNADAYFRFVD
DAARLGVNVPIVPGIMPITNYSQMMRFSDMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTALCERLLADGVPGLHFYTLNAAAATKAMWQRLGL
>A0A0D3C671|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica oleracea var. oleracea|TrEMBL
MKVIDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGSTA
DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK
FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYQSDLEYLK
KKVDAGADLIVTQLFFDTDMLLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCKTK
IPAEVMAALEPIQDNEEAVKAYGIHLGTEMCKKILAHGIKSLHLYTLNMEKSALSILMNL
GMIEESKISRSLPWRRPANVFRIKEDVRPIFWANRPKSYISRTKAWENFPQGRWGDSRSA
SYGALTDHQFSRPRARDKKLQQEWVVPLKSVEDIHEKFTELCLGNLKSSPWSELDGLQPE
TKIINEQLVKVNSKGFLTINSQPSVNAERSDSSTVGWGGPGGYVYQKAYLEFFCSKDKLD
ALVEICKALPSITYIAMNKGETWVSNTSQSDVNAVTWGVFPAKEIIQPTIVDPSSFNVWK
DEAFETWSRNWANLYPEAADPSRNLLEEVKNSYYLVSLVENDYINGNIFKVFSDL
>A0A3D4KZN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKIPELFKNGHTVFSFEVFPPKKDADVSVIYDTLDQLGDLHPDFISVTYGAGGSAAGATT
TELVRHIKENLGTESIAHLTCVNSTHADIDEKIKEFEANGIENVLALRGDINPNFPPKNE
FLHASDLIEYMKPRSNLSFSGGCYPEVHPEASSMVEDILHLKKKVDAGASHLISQLFFDN
SSFIEFLEKARIAGIDVPIEAGIMPCVNAKSVQRMVSMCGASLPVKFTKMINRYGDNPEA
MRDAGIAYAVDQIIDLVAHGVDGIHLYTMNNPYVARKITESIEKVIRCDK
>A0A4T0DVC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHATTSEMPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVN
VTWGAGGSTSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDEALEQAKALGIRNILAL
RGDPPRSDEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQS
HPEHQHATYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGL
MPIQSYQILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSG
PKGFHFYTLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSIANS
APQNRVVIDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDD
FPNGRWGDARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIP
WSEEGLNPETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVE
FFCSHEDWTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIE
AVSFRAWAEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWNMLL
EA
>A0A0G3G725|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioalkalivibrio versutus|TrEMBL
MSAQERVYSVEFFPPKDEAGAERLAKARKRLGALNPEFYSVTFGAGGSTRDRTLETVRDI
IDHDGIPAAPHVSCISSTKDELRDLLSTYRDSGVKRIVALRGDLPSGTKHSGGDFRYASE
LVEFVRAEFGDQFKIEVAAYPEFHPQAPNAEKDLENFKTKVDAGADAAITQYFYNPDAYV
AFMERVEKMGITIPIIAGIMPITNYTQIVRFSEMCGAEIPRYIRKRMEAYGDDKESIRKF
GIEVATRLTDDLLDNGAPGIHFYSMNQAGPTEQIWKALDLDNRK
>A0A6I4SSU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Croceibacterium salegens|TrEMBL
MSYAAIHPNWEKPRDNMVDGYSLEMTAKEIEGLREAAPLIRPKTQIAVTFLPGEEMEQRV
EAAVLVRELGFEPIVHLSARRLTSLEELDKYVSDISSKAGVKRVFIIAGDPPEPEGPFSD
SLQIIESGVLEKYGIEIVGVGGHPEGHPNVSKSDLWVWMEKKLAAVRAHGMVPLVVTQFA
FDDDAIVEWIKEMRGRGIDVPVRLGIPGPAGIKRLLGFAKRCGVGASASVMKKYGVSLTN
LIGSAGPDKLVASLEKGLTPELGRVRLHLYPFGALKASAEWINDYEAKH
>Q8DI21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1)|TrEMBL
MCPPKGRDASTMLRQAAHLKGRVHAVNVTDGSRAVLRMSSWAAAYLLQQQGFEPICQIAC
RDRNRIALQADLMGIAALGLRNILALTGDPVKAGDHPQAKPVFDLESVRLLRVIGQLNRG
VDSEERPLADGATHFFAGAAVDPQSASWSGLQQRFERKLAAGAQFFQTQLITDFERLAKF
MDQIAADCGRPILAGIFLLKSAKNALFINRAVPGASIPQHIIDRLAAAPDPLDEGITIAA
EQVQQARELCQGVHLMAVRREDLIPEILNRAGIPPLSASPAPLAKRPHSP
>A0A0K9S3H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spinacia oleracea|TrEMBL
MKVIDKIKAAEAENKSLFSFEYFAPKTENGVENLLETMERMVVQVHAPCFCDITWSTPTA
NVTMEIANRMQNSVCVEAMMHITCANMPVEKIDIALDTIKSNGLQNVLALRGDPPPGEDQ
FVPVEGGFSCALDLVKHMRSKYGDYFGIAVSGYPEAHPSVFGPDGVASPEAYASDLAYLK
RKIPEEISDALERIKDNEDAVRAYGIRLGTKMCKKILGSGVKHLHLYTLNKEESSLRILM
NLGLIEESTIPTPISQLTPQDAPVSIPTSARMDSEDVEVQKTLYL
>A0A7G6WNT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. NBSH8|TrEMBL
MLPTRIEIIPSTGIVDQVRALVPLTTTLTITCLPHHGVERTMRTSVELSDFGYTVIPHLA
ARSIHDRAELTRIMRDCDGAGIGEVFVIGGDRKQPAGPYGSALPLLEDLAQYTGGRMRAG
VAGYPEGHPTVAALDLLEALQDKQLLATHVVTQMCFDAPKILDFAALLRREGVNLPVWAG
VAGSVPRTKLLALATQIGVGSSLKFLSSKGTLARKLLSGDRYSPHTLVAGLESQPGIAGI
HLYSFNNLDAVPNEAGHASSPTALQPALIRGAAREQ
>A0A3D1Z433|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp|TrEMBL
MSYSHAGHIDALNHNIADLEGKINVSFEFFPPSSEKMEETLWNSIHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASRDELKEIAQDYWNNGIRDIVALRGD
LPPNGGKPDMYASDLVELLKGVADFDISVAAYPEIHPEAKNAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVSNYKQAKRFADMTNVRIPSWMAKQYE
GLDDDPVTRQMVGASQAIDMVRTLSREGVKDFHFYTLNRSEMTYALCHTLGVRPS
>A0A852ML98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pteruthius melanotis|TrEMBL
MVNETQHTCSTSSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEADGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCQELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A1W9JD79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium ST_bin12|TrEMBL
MKQNLPLSFEFFPPKTADGISNLRETRAQLARYNPDFFSVTFGAGGSTTDRTKETVFEIQ
AEGYQAAPHISCISSSKEEIRELLSAYKAKGIKRLVTLRGDVPSGEVSVGDFKYANELVS
FIREYSGDWFHLEVAAYPEFHPEALSAAKDMANFKRKVESGADSAITQYFYNADAYFRFV
DSCEADGITIPIVPGIMPIYNYTQLARFSGVCGAEIPRWLRLRLEAYADDLPSLRALGVD
VVSELCETLLAWGVPSLHFYTLNQAGTISKIIDNLELK
>A0A5R8P9X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia cyriacigeorgica|TrEMBL
MTFDNVRGRSTPGRPSSAPPIVSGTPSVVQSLRLHSSRAVPFSVEFNPPRDAAGEARLWR
AVRTFERMHPAFVSMTYGAGGSTKDRTVRVTGELAGETTLLPVAHLTAVGHSVAELRSLV
GAYADSGIRNILVLRGDPPGDPLGEWHKHPEGVEYAEDLVRIVRDLGDFHVGVASFPQGH
HRSPDLDHDTRFLAAKLRAGAEYSITQMFFDVEHYLRLRDRLIAMDPVEGAKPIIPELMP
ITSLRTVKRAEELCGRPLPRAVIERLERAAGSGSEEDAAAVRAVGIEIATEMGQRLIDEG
APCLHFITLNFAKATGEVLTNLGYGVTAAPISA
>A0A1M5FB27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium micromati|TrEMBL
MAGGRGTIMKVTQHIEEAKGETLFTFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTS
REEFIYVDKGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVD
CHYLGINNVMALRGDAMKEEQSFVPKMGGNCHAIDLVQQIKLLNEGKYLHDVIHVDNRSD
FCIGVAGYPEKHLESPSLLSDLKRLKEKVDAGADYVVTQMFFDNEKYFQFVAKAREMGIT
VPIIPGIKPLAVQRHLQVLPQIFRIDLPEDLIQAVDDCKDNAAIKQVGIEWAIQQSLELK
AAGVPVLHYYSMGKSENIRQIASQLF
>A0A285EGU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus sabuli|TrEMBL
MSVEIPGRTRAPTGSGSPTVDGRPTRQRARVALERALREASYEVLPLRGAEESVVEHVPR
SVPLTVTVTEAKGLTPTLELAERLSGHGFAATPHLAARLVRDRGHLDDIVGRLRAAGVDG
VFVVGGDAADPAGTFPDALSLLEELETAGHSFRQVGIGGYPEGHGHISPELIERALERKA
PHATHVITQLCFSAATTTAWAREAKRRGVDLPIRVGLPGAVTRQKLIRISATLGLGRSAR
FLTKQHGLLWRFFLPHGYQPDRLVERLAPTLGDPGHGLHGVHLFTFNEVQRTEAWRQAWL
TRLADAGCGDR
>A0A2J9QNE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella multocida|TrEMBL
MSYAREIDTLNQHIADLNGKINVSFEFFPPKNEKMESILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLEAAPHLTGIDATPEELIEIAKDYWNSGIRRIVALRGDEP
KGYAKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLVKMAAITNVKIPAWLAKNYEGL
DDDPTTRNLVAASVAMDMVRVLSREGVNDFHFYTLNRSELTYAICHTLGIRPGSE
>A0A2V1GYL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibaculum spongiae|TrEMBL
MRSQLKYRVDYSFEFFPPKTDKGAENIKVAAQQLAALNPKFFSCTFGAGGSTQEKTGETV
SMIKEVTGIATAPHLSCIGSKKDNIRQMLLDYKAQGIDRIVALRGDMPSGMGSPGELRFA
NELVEFIREVTGDHFHIEVAAYPEFHPQSFNADDDLKNFKRKVEAGANSAITQYFFNPDS
YFRYVDSLEKIGVDIPVVPGIMPITNYAQLARFSHMCGAEIPRWLRKRLEGFYDDREAIA
DYGIDVISELCRSLLEGGAPGLHFYTLNRSDTSIKIFKNLGLTD
>A0A1M6IJZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoclostridium caenicola|TrEMBL
MKLSQLFGKNKQTLAFEIFPPKPEVPMETLFESIPGFKELSPDYISVTYGAGGSSRGRTV
EIASRLKNTYGIEAMVHLTCVGHTMEQIDEILDSLKRENIENILALRGDPPIDQPDFDFS
RGDFRHANELIAHIRKVGDFCIAAAAYLEGHVDSKRLDEDRRWLKEKVDAGVDFLITQLF
FDNRLYFDFLDRAAQIGINCPIVPGIMPIFNAKIKTMTARSGCSIPAKLVLMIDKYQDNP
EDLRKAGIEYAAKQIRELLDGGAPGIHLYTMNRLKSTIEILKAAGLR
>A0A0P8B7J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium HLUCCA09|TrEMBL
MALLSFKTRDPAPTPAATAAFLKGYSIEVMPRTAAKVADFHALLPEATRVTIAHIAGTPI
DDMVATATRLARAGYEVMPHFPARNIPDIATLEDWIARYQGEAGVREALLLAGGEAQPAG
ALHSSMQLLETGLFDKAGFTRLHVAGHPEGNRDIDPNGGERGVMEALRWKQAFSERTDAK
MALVTQFAFEAAPIVAWADRLRHAGIDLPIHVGVAGPARLQTMIKYAIACGVGPSLRVLQ
RRARDVTKLVKPYEPNEMLGELAAHKRADPAFQVAQVHVFPLGGIAASAEWAARLLAAAP
DPREAAAR
>A0A4Q9XL41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bowmanella sp. JS7-9|TrEMBL
MVSYAQGIDALNQSVSELRNINVSFEFFPPRTEQMEKTLWKSVERLAPLKPKFMSVTYGA
NSGERDRTHDIVKQIHHETGVTTAPHLTCVDASADELRAIAKDYWDNGIRRIVALRGDLP
QGMGKPEMYAVDLVRLLKDVADFDVTVAAYPEVHPEAPNSQFDLLNLRKKAEAGASTAIT
QFFFDAEVFLRFRDRAAAAGIDLEIIPGILPVTNYQTLVRFAGMTNVHVPDWLHKQFSGL
DDDDQTTRNLLGANIAMDMVKVLAKEGVRDFHFYTLNRSELSYAICHMLGQRAG
>A3TKC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janibacter sp. HTCC2649|TrEMBL
MAPRSIPGLLAGERPSVSFEFFPPKDDASEAALWDAIRRLERVRPDFVSVTYGAGGSTQD
RTVRVTERIARETTLTPLGHLTCVGASVEDIRRVIGQYAAAGVRNILALRGDPPGEPGGE
WVAHPEGLNHATDLVALIRTLGDFTIGVAAFPDVHPASPNLDHDVEVMIKKADAGASFAV
TQMVFDADSYLRLRDRVAEHRDLPITPGLMPVTNLKQITRMTELMGTPLPAAVVDRLQAV
SEDPAAVRSVGVEIATEIAQRMLAEGAPGLHFITMNRSTATLEVYENLGLSAGAR
>A0A1H2SU36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aidingimonas halophila|TrEMBL
MNSLVSRSAAPSELVLEAVPPEIQQGERGIEAALEKVEGLHREVGLDAVNIPEIREESSK
SSKGERRKPFAPRVEPRVLAHRIQEQLGVPCIINRVVVHLERERQLDWFRETHEDYGVNR
VVLVGGERSDRQYPGPSVPEATRLLKDRPDAPDIEVGNICIPSRPDEAARMKRKIASGAD
FFTTQVIFHADEVTSLLDSIGTDVGSSRTPAILISLAPVRSERNIRFLHWLGVNLSNDLE
NWLISDPEAVTERSLSHIGDVWRDIAEHAAETASPFPISANLAPIGRIPAATTISLARTL
REHRIHAPRAMGSVLT
>A0A2G2WUP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum baccatum|TrEMBL
MKVIEKIQESIKDDKVVFSFEFFPPKTEDGVDNLFERMERMVSHNPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALENIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGLATPEAYEKDLAYLK
QKVDAGADLIVTQLFYDTDNFLKFVNDCHQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKIMASGIKTLHLYTLNMEKSALAILMNL
GLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDEFPHGRWGNAQNP
SYGALSDYQFMRARSRDKKLQEEWAVALNSVEDIYERFMNYCLGKLRSCPWSELDGLQAE
TKIIDEHLSNINTKGFLTINSQPAVNGAKSDAPLVGWGGPGGYVYQKAYLEFFCSREKLT
AVVEKCKAFPFLTYMAVNKQGNFISNIHQIDVNAVTWGVFPAKEIVQPTIVDPVSFMVWK
DEAFEIWSRGWAQLYPENDPSRKLLEQVQNSYFLVSLVDNDYINGDLFAIFKDI
>A0A1E4HG18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. SCN 67-45|TrEMBL
MPSISFEFFPPKTDDQRAQLDRAAQALKAHRPEYASVTFGAGGSTLSYTGDTVARLHTQH
GLNVAPHLSCMGGTRAEIATLLDGYRAAGYRRIVALRGDMPSGMATAGDFRYAAELVAFI
RRHCGDHFHIEVAAYPETHPQADDALRDLMHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VRKLGVNVPIVPGIMPISNYSQLRRFSEMCGAEIPRWIAKRMQAHGDDADAVRELGAEVV
AQLCRRLLDGGAPGLHFYTLNRARATQAVLQQLA
>A0A5X3P660|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Weslaco|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6H3K412|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT2-10|TrEMBL
MSTTSEPDCGRIPFSFELYPPRSDAAATALHATIATMASAGPDFISVTYGANGSSRSSSL
EVLTHILKTTTVDPMAHLTCVGSSSLEASRLIREFLDAGVRSFLALRGDPPEGAGEGEAF
LGDLGSAAELVQLIHRVQAERVPYRETVIPGIPGARAVKTEREKVRIAVAAFPNGHPRSR
STSQDIDTLLAKQAAGANLAITQLFFHADNYLSFIQRARTAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIQLEVEPTREGQREIGTRHATDLARELIAGGAPGLHLYAFNQAD
TVLAVLAGAGLIKPVLG
>A0A1J0LVK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus brockianus|TrEMBL
MKIRDLLKNRQGPLFSFEFFPPKTAEGEEALFRTMAELKAFRPAFVSITYGAMGSTRERS
VAWARRILALGLTPLAHLTVAGQSREEVEEVLGRFVESGVENLLALRGDPPQGERVFRPH
PEGFRYAAELVALIRARYGEGVSVGGAAYPEGHPESESLQADLQHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRMGIHIPILPGIMPITNYAQLRRFTEVCGASIPGPLLSQLERHQ
DDPKAILEIGVDHATRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGFRPGA
>Q7S830|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)|TrEMBL
MHIREMLADAERTKAPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIA
ELTCEMVAQAQAYLGLETCMHLTCTDMGEEKVNNALQRAYKAGCTNILALRGDPPREKER
WEAAEGGFQYARDLVAHIRKLYGDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGASF
IVTQMFYDVDNFLRWVKRVRERGITIPIIPGIMPIATYASFIRRANHMNCKIPEEWMAKL
EPVKNDDVAVREIGKTLVAEMCRKIVDAGIRHLHFYTMNLAQATRMVLEELDWLPSPNRP
LKRALPWKQSLGSGRRDEDVRPIFWRNRNKSYITRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNELNRKKWGEPQTVKDIANLFVRYLNQELEYLPWSEAPISSEAELIKDDLIA
LNNRGLITINSQPAVNGVKSTHPVHGWGPANGYVYQKAYLELLVSPELFPEIKRRIEDHP
DITYYAVTKSGNLHTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFQLGLEW
ARCYDADTPSRLLIEEIMDKWYLINIVNNDFHQPRTIFEILNDLSLPDLEKVYTPAHTNG
ATNGVPEASTVPQ
>A0A1F8XWR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium GWB2_55_19|TrEMBL
MGFKEDLRSGKFVITAEICPPRGTEAAPFIEKARLLKGRISAANVTDNQRAVMRLSSLAC
SILLMKEGLEPVFQMTCRDRNRLAMQSDLLGAWVLGVRNVLALTGDHVSAGDHREAKAVF
DLDSVQLVSMITTLNSGKNMNGVELRGGTDFFIGAVVAPEASPWEPEEIKFEKKVEAGAR
FFQTQAIFDMDKFKRFFDGAAKTEASILGGILLLKSAKMANYLNANVPGVHVPQGLIDEL
EGAPDQLEKGIEIASRQVRELKKFCHGAHIMAIGQEESVVRIIEEA
>A0A4R6LRB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enemella evansiae|TrEMBL
MTESSTRVPGPAAAPAPVTLSQLARNVSFEVMPFAKTEGLVLEHVPTEVPLSITVTEAKG
LEPTLALTERLTQQGYRATPHLAARLFTGDQQVAEVADRLTEAGVTSIFVIGGDAPEPAG
EFTDARGLLDSLERQGRRFETVSIGGYPEGHAKIDDATLSEALRAKAPHANGLITQACFD
AKVLGAWAADVARDGISLPIKVGLPGPVNRQKLIRISAGLGLGQSARFLAKQQNMVWRFL
LPGAYDPMKLVKKLGAVTARTPTHIAGLHLFTFNEVAGAERWRQRLLTATREGH
>A0A0M9DT59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium 336/3|TrEMBL
MTKITEYIKNSDKTLFSFEILPPLKGESIQQLFKAIEPLMDIKPKFIDVTYHREEYVYKK
RENGLLERQRIKKRPGTVGICAAIMNYFKIDAVPHIICGGFSKEETENALIDLQFLGIDN
VLVLRGDAIKSEGAFFSEPNGHAYASELLEQVVKMNKGKYLEEGLQASATNFCIGVAGYP
EKHFEAPNLNTDLKYLKLKQDLGADYIVTQMFFDNQKYFDFVAKCREIGITIPIIPGLKP
ITTKKQLTVLPSIFHIDMPDTLVKAVEKCKTNDEVKQVGIEWGIQQSKELMFAGVPVLHY
YSMSKSDAVKQIAEALF
>A0A098RYN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. H41|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNAEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLATAAHLTCVDASRDEVHQVVDEFRNAGVRHFVALRGDPSTGIGTAYQ
PHPQGYENAAALVKGLKELGDFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPAFLDERFEGYD
EDLEGRARVAAEVAAEQIADLQRRGVSEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A173TEK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia intestinalis|TrEMBL
MKFFRFVDDCRIAEINVPVIPGIMPVINAAQIRRMVTMCGASFPVRFQKIIHKYEDNKEA
LFDAGMSYALSQIIDLLVSDIDGIHLYTMNNPLVARKICEGIRHII
>A0A0L7AX79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium breve MCC 1128|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPVVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQAVGEFNHASDLV
SYIRSVKPDLKVFGACYPEGHYQADTIDQDIENLKIKVDAGATHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNTEPLFLGTQG
>A0A855WAI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter schindleri|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLAPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKSTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMMKHKIAGIVITPHMLRVLAQEKQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVET
KKELVPQLAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASFWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A7W8HUG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium rosettiformans|TrEMBL
MAQIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKVF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGFHEKCFILVGV
GPLASAKTAKWIRSNVPGIHIPDHVIKRLEGAEDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGILKGRKPWKREHARADDMAAERMREIGSDPVQDQQEMAAKAA
HPQPH
>A0A498D0U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter cumulans|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLADFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIKRFCEKANAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTDSIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVQDLGLA
>A0A167IAA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. HI0063|TrEMBL
MREAQRALEAPMFSDLAGDIEVSFEFFPPKSEKMSETLWQSVETLKPLDPRFVSVTYGAG
GSTRERTHEQVVRIQNEAQIPAAAHLTCVAATREEVDAVARHYWEEGIRHIVALRGDAPD
SDKGYSPHPGGYENAVDLIKGLKKVGDFEISAAAYPEMHPDSKDRQADLDNLKAKFDAGA
TRAITQFFFEPECFFDFRDRAAAAGIEGEIVPGIMPVMSFAAVQKMSGLCGTAIPPWMEG
LFEGLDEKPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKVA
S
>A0A3N5W9F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MNREPRRLKGVLEQGQFAVTVEYNPPKGTNINGLLDNAKQLLGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGLRNVLCLTGDYPTVGDHKD
AKPVYDLDSVQMMGLVQGLNNGRDYAGNKLDGATDFTIGAAVTPEADLVGPVLAKFEVKV
KAGAQFFQTQAVYNPEQFAAFMNAVRRFKVKVLAGILLLRNAKMAEFMNANIPGMSVPQA
MIDELRAAGDKSEEVGVEIAVRSIKAVRPHCDGVHIMAIKGTHRLGEIITKAQLA
>A0A2E3MLH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MSLASIYQQQKVAVSCELFPPKTPQGDVALLRHVAKLMEWSPAFVTCTYGAGGSTRDKTL
DVVQAVKRDFAVPVASHLTCVGASVDQLRQFLQEALQRGVDHIVALRGDPPSGANAFRPV
EGGLQYANELVALIRDEFPEFGVAVAGYPETHREAANSEADLQNLLRKVRTGADVVLTQL
FYDNQRFFTFRDRCRALGIDVPIVPGILPITNLSQIKRITSLCGAALPDTLLQQLAARED
ADWQYRVGVDFATQQVAELVKGGVPGIHFYVLNKSLATCEVLERVDL
>A0A3B8L2V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MRTLPEIYCDTSSVSRLPVSVEIFPPKTSDGDQALFDTLDLLVTYRPAFVSCTYGAGGST
RDRTLELCQKIESRYDTVAMAHLTCVGSTRDEL
>A0A350CA95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MRLTDLFNSRRFVLSIEMFPPKTAETSEALKRSLLSLNRYNPAFVSCTYGAGGSTRGQTL
DWCQWIQQTLQRPAMAHFTCVSSTVDELSDWLHQAWQSGVRNIMSLRGDPPAGQQVFTAA
EGGLNHASELTALIRRLYPEMGIGVAGYPEKHVEAPSLDADLENLKIKVDAGADAVFTQL
FFINRSFFEFRDQCAARGITVPIVPGIMPITDFARIRRITSMCGSVIPLELATQLEAVRD
DAAAQFEIGTEHAIRQCRELQAEGVPGIHFYALNKSDACERILNALSLPLA
>Q66FJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pseudotuberculosis serotype I (strain IP32953)|TrEMBL
MERKLSFEMNSAKNEKEMENIFKLIEFTDTLDPIYYTVNTEIGSSVWSDTYRTVIELREK
TDVSLIPHITINNKKEREIMQIIEKYINVGICEFFVIRGDKHVYDQDNPINYGVELIELI
RRSHKHIGIKTSLYPDFHKETTEVKEEIDWNERKYQLGVNEFISQLTLNTNALDFLSHWV
DKERPFTPSIMPLGNFSFIEKFTSSNSIDYPLWIKKFANSKSNSNEDKENIGIEIIRFLC
REYLNQRERLHVFTLNKVDVMKKIFQ
>A0A1D7UC46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea vaviloviae|TrEMBL
MSDSYLQPARSYGTLGSLIEGFSLEMTARDADVLAEAVGDLPAATRIAVTYLPGEEMAAR
VAAAASIRNYGHIPVPHISARRLTSVLELESFLDRLSIEASIDRAFVVGGDLRAPAGPYP
DAKSVIASGLLAKYGLSRIGVAGYPEGHPSISEHDLMLDLRTKLAMLRDLGHEGVVNTQF
SFDAEAILQWLEALRNDGVTATVRVGIPGPTTVKSLLRFAARCGVGASTAVLQKYGISLT
KLLSPVGPDRLLAELGARLNAERHGDVRLHFYPFGGLAGTARWAKTLVR
>A0A326RR64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus aquaeductus|TrEMBL
MKITEHLKNAKSTLFSFEILPPLKGQSLKELLEGIEPLMEFKPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRYHVDAVPHLLCGGFTKEETENALIDLNFIGVDNV
LALRGDAPKTEGRFIPEPEGHQFATELVEQIVRMNQGKYLHEETENSFHTDFCVGVAGYP
EKHFEAPSMKFDLKYLKEKVDRGAEYIVTQMFFDNQKYFEYVRKVREAGIEVPIIPGIKP
ITTLGQITMLPRTFFLDLPDALTDELEKCKTNAEVKEVGIAWAIGQCKELVAANVPSLHF
YTMSKADATYKIAKEVF
>A0A2D5YU27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MKPVTRRVPAQPLSTESTTADAPPRAIPNYLAQLDRKTVVLVELDPPKNTDLPKMLRSAR
QLAEAGADAITLGDSPLAGLRMNGLMIGPTIEQEIDIPVICHLACRDRNVIGTQSLLLGA
DALGLRSVLALTGDPAKVGDHPDAVSVYELNSFKLVELINRMNHGQTLAGRSIGRPTAFE
IGVAFNPNKRDVMPEVRRLKRKAERGATFALTQAVFDADTMRVACEAAHEHVDIPVFAGV
FPLLSDRHAEFLHNEFPGVTVCDDVRHRMAAAAPDKDRMAAEGMAIARDLIDAFRESADG
LYLIPPLNRAAVAVELLHYIHATEPAPQS
>A0A4V1AKT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium salivictor|TrEMBL
MKITEHINNAKGKTLFSIEIVPPTKGTGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERKITRMRPGTLGICAAIQHKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGIEN
IMALRGDAMKGQQYFEPTEGGHKNAVDLVRQMNDLGRGKYLHDEKICDGNNKFCIGVAGY
PEKHIEAPSMNYDLKWLKQKVDAGADYVVSQMFFDNKKFIDFVKSAREIGINVPIIPGIK
PIATKKQLQLLPQVFKIDLPEDLISAVENAKDNAAVKQIGIEWTINQCRELLDFGVPVLH
FYSMGKSDNIKKIARELF
>A0A099NZC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pichia kudriavzevii|TrEMBL
MKITEKLQQAHRAEDAPATFSFEYFTPKTSQGVQNLYDRMDRMYNLNPLFIDITWNAGGR
SSNLTSEMVHTTSTVLGLETCMHLTCTNMPLELIDNALQQAYDSGCQNILALRGDPPLDG
SESTGDFKYAKDLIRHIRNKFGDYFCIGVAGYPENHPEEADEMKNLQYLKIKQDEGADFV
VTQLAYDVNIFIEWVQKCRQVGITMPIIPGIMPISNYNAFLRRAKWNEVSIPQSFLDRLE
PIKDDDAKVREEGALLMTEFCSKLLESKLINHLHFYTMNLEKSTLMLLENLNLISCASKI
NYENENSKPWRRSLNPSRETENVRPIFWKNRKFSYIQRTNAWDEFPNGRWGDSRSPAFGG
LDLLEHEIIRHSPAKILSLWDKPSNPMELGNLIIAYLENRIHCLPWSDTQVTSEIEPIKQ
SLIDLNKHGVLTINSQPKINGVRSDDLVFGWGPSNGYVYQKQYLEFLLPKSKMDLLISKI
ESVNKEYNYNILNYFIADADSNNVLGSNVIESADVNAVTWGCFPGKEVAQPTIVEKVSFI
AWKDELFLILKKWSNVLKSSSVDAQTQPDETDRLSDLNSANFIESLINEYVLVNIVDNDY
VHPSDRIFSLFNDI
>A0A4V4HV75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botrytis galanthina|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YRAIDEKSGDTPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDGFEQKLRDHPSGAFKNIPIIPGMMPIQSYQMI
KRTTKLSHAKLPSTIITRLDAVRGDDEMVKKVGVDILSEMVEHLKNTKSQYSGPRGFHFY
TLNLEKAVSFILERTELIPDAETVAALEPEYVPTIPDIADLMSIHSGSHKRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATAQEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGLKSSDSIFGWGPKNGFVFQKAFVELFL
PTADWKTLHAKLTSPELRDTVSFYASNAKGDFISSDEAVGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSETRKIIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLN
>A0A432W110|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliidiomarina minuta|TrEMBL
MSLSHAQHLELLNQSISELNNDTQVSFEFFPPGTPEAEQTLWKALNRLAPLKPRFVSVTY
GHGEESRQRTHNMIKQIHDRTGLIATPHLTCIDTPAEELRDIARDYWKNGIRHIVALRGD
AQPGRLNTGQSALDLIHLLKQEHDFDISVAAYPNVHPEARSPQADLMELKRKVDAGASRA
ITQFFFDVESYLRFRDRCVSVGIEAEIVPGILPIGNFGTLQRFAKLTNVRVPYWLQRRFN
GLEDDPTTRSLVGASVAIDQVRVLSREGVGEFHFYTLNRAEQTYAICHTLGLRPPEIEHA
PQQPALQTANG
>A0A2S6JST8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microterricola pindariensis|TrEMBL
MTPVSFELFPPRTDAAALALGRTIDKLAEADPAFISVTYGAGGSSRERSLTVLRYILEHT
AVEPMAHLTCVGSSHAEANSLVRQFLDAGITSFLALRGDPPSGVTGPAELGDLGSAAELV
QLIHRVQEEREPFSQKRVPGASQGSRIARRRRPERVAVAAFPNGHPRARGSSADVDSLLA
KQVAGATLAITQLFFHADDYLSFVDRARTAGVTIDIVPGLMPATTPTRLARIAELTGEEI
PAELEIALEVEPSEERQHEIGVDYIARVAAEVLAGGAPGLHLYTFNQHRAVLGVLERLGR
MPAVAGR
>A0A855KLJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MPR-AND1A|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A2V6ULX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFSERLAEGPLLCDGAMGTVLYARGVPLDACFDVLNLNNPRVVQAVHADYVAAGADA
IETNTFGANRFKLGVHGVEAQLREINRRGVRLARDVRESAGRDVWVLGSIGPLGKYLEPL
GTVTAAEGREAFGEQAEALLEGGVDAFVVETFSDLAEIALAVEAIRAITDLPVVAQMAFT
DEGVTFMGRSPADVARTLRALGVQALGANCSIGSSTLYDVLERMVAEASGLPLAIQPNAG
LPSRIGERLIYLSSPGYMADYAGRMVEAGARLVGGCCGTTPQHTAAMRETLDRLLPGPRR
VVARAPVTARPAAVETPGLARTLPPTPLARKLRAREFVVTVELDPPRGHTVDKLVQGAKL
LKEKGVEIVDINDGSLGRVRMSVLATALLIRDHTGLDVNMHFTCRDRNLMGIQADLLGAH
ALDIRNILAMTGDPPRTGDYANATAVFDVDGVGLIGILRRMNEGLDATGSSIGDPTGFCI
GAALNPAAEDPDHEIERMHRKIEAGASWLQTQPVYDLEALERFLARAGRIPVPVLVGILP
LHSFRHAEFLHNEVPGITVPDVARARLRDAGESALRAGIEMAQALVAEVRRRHAGAYLMP
SFGRFEVVAEVLDALH
>A0A2V6T3H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MTQPFLDRLAERPILADGAMGTMLYARGVPIDACFDVLNLHDPRAVQAIHREYVTAGADL
LETNTFGANRFKLAVHGLDARVREINRAGVRLARDVRETMGRDVLILGSVGPLGKYLQPI
GTVGEEEARAAFREQAEGLVEGGVDGFVAETFSDIRELRVAVEAIRLVSADLPVVASLAF
NEERRTFMGQAPADVGRELQALPVQVIGANCSVGPSVLYDVLVLLRQAAPDGLVAIQPNA
GLPSRLGERLIYLSSPVYMADYAARMLDAGARIVGGCCGTTPEHVRAMREVVDRHVPDQA
RGSSRSVFIAPAASLPEALPLAATTEPTRLLARLHAREFLVTVELDPPRGHNIEKLVQGA
KLLAERGVEVVDINDGSLGRVRMSVLPTAILVHEATGLDINIHFTCRDRNLMGIQADLLG
AHALGIRNILAMTGDPPRVGDYVNATAVFDVDAIGLVRILRGMNEGVDATGNSVGEPTSF
AIGVALDPGVADPARETERLLAKIEAGAMWVQTQPVYDLETLDGFLARVGRLPVPVVVGI
LPLHSSRHAEFLHNEVPGITVPEEIRRRLREAGDHALRVGIETAQAILAEVRRRYAGAYL
MPSFGRFEVVAEVLEAVR
>A0A7Y6SUX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. 41S5|TrEMBL
MTETISSLPNGQRVPKTPKISFEFFPPKTEEMERSLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTISRILRETDLLPAAHLTCVSASRGEIDEIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAAIKKRHADIEISVSAYPEKHPEAADFDADIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDRVRTRGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPTGA
QKAA
>A0A6G1LNL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Teratosphaeria nubilosa|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGIGPAFVDITWGAGGRMS
NLTVEMVKVAQSAYGLETCMHLTCTDMAKEKIDNALKDAYNAGCTNILALRGDPPREKEK
WEQSNGTAFRYAEDLIKYIKSKYGKHFDIGVAGYPEGLDDGTDAEGHIPYLKQKVDAGGT
FIVTQMVYDADNFIRWAKKVRAAGVPDSVPIIPGVMPIQTYDAFLRRAKWTQCRIPPEWL
EALEPVKHDDAAVREIGKGLIADFCRKLLDAGVTMHLHFYTMNLAASTEMVLQELAMTPA
PDCHDPDIKPLPWRQSLGLNRRDENVRPIFWRNRKQSYVARTQDWDEFPNGRWGDSRSPA
FGSLDAYGIGLKGTNEANKKLWGEPKSIQDIADLFVGYISGKVKALPWSESPISDEADVL
RQDLIDLNARGLLTINSQPAVDGAKSTHPVYGWGPRNGYVYQKAYLEVLIHPSILPTLIE
RVGKTEDITYYAVNNSGELQTNVRDEAGAGPNAVTWGVFPGKEIVQPTIVETISFLAWRD
EFYYLGSEWSKCYDEGSESRKLIKEITESWYLVNIVDNDFRNKNGIPRLFDGLKVEGVEP
KAKASTNGVNGHAETNGVAQADGVEAVAKDEHAVNHN
>A0A3P1UKX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium canifelinum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNEKVGLEEVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHFTCIGSKKEEIDRVLEDLERNNIENILALRGDYPVDRELELGD
FNYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRK
>A0A0M0HWY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio hepatarius|TrEMBL
MGYTHAGHIDALNQNIADFSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLIAAPHLTCIDANRDELIQIADDYWRNGIENIVALRGD
IPPGGGKPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVRVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRPTVA
>A0A1E5KYT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus rivorum|TrEMBL
MKIGPLFKQKTVFSFEIFPPRPTASIQTIYSTLDRLKGLEPDFISVTFGAGGNINDQLTV
DIAEKIQKEHFLPSVAHLPAANLTKAEVRDILHELSEKKVKNILALRGDLLPDSTPKTDF
KYASDLVQFIKENGDFHVVGACYPEVHAEAKNSVEDIKSLKIKVDSGVDQLITQLFFDNR
SFYNFKEKCEIANIDVPIQAGIMPVVNKKQVERIVKMSDVSLPEKFIKMMEKYEHNPEAF
RDAGIAYAINQIVDLVAQGVDGIHLYTMNNPYVAQRIRVATRSLFNVPKEPSS
>A0A4Y9QCU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. CT_GayMR16|TrEMBL
MQPASDVPRVGCPKRMVFGPCGGVRDDGRCELNEDPCVFLSDPLVRWPGPPVQPRTPSTL
LDRATHAPVVLADLSVIPFDPASVRRVVDVLAPVADGLLVGEHANRPDFPPTMFAAEVIG
AGGRVWTTLACRDRNRVVLEQELAGLAAVGVDGVLCVTGDGRGASVRPGVTQVFDLDGIR
LAGLAAGMGLPVAVPESPEAPPVELRPARVAEKQRAGAQLCVLNHVSSPARVAAFVEAAR
GAGATLPFIAGVAVYTDEPSARVLQRFPGLRLDGAVVERVLAAPDPRVAGIAAAVAEARA
LLAIPGVVGVNLSGTGSSSGVDDGAQVKAEVAALLRGAL
>A0A1V6J685|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin013|TrEMBL
MKLTDIFKVSEKTFSFEFYPPRDEIAAVDFGLNIGQLIKLSPSFVSVTYGAGGSTQSRTF
DLVDYLKNRVGLNTVAHYTCVGSTRSRTLEDLKTLRKLGLQNFMLLRGDPEVGSKYGFIP
CYDGFANATELITFAREFIDDCCIGGGAYPEVHPESPSAEIDMRNLKKKVDAGCDFLITQ
FFFDNKRYFDFVSRARKAGIKCRIIPGIIPLTKYSQLERFVNLSRASVPPAFLEQLESNR
YNPEAVYKAGMDFAIRQCRDLLMLGAPGLHFYTLNKSRATVEIYQTLMVR
>A0A2A2EHA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium italicum|TrEMBL
MSIFSLEIFPPKRTAPVGTIYDTLDGLQGLEPAFISVTYGTGKSVDRTATARIANTVRAE
YGIPAVAHLTAQYLDEAGAEEALDLFDQAKVAGVLALRGDRNPDREPANVFHHASDLAAF
IRERRPGLPIYGACYPEKHPQAASLDEDIDNLKRKVDAGVTHLISQLFYDDGDFLRFRDK
ARAAGIDVPIEAGIMPVVNCASVRHMAGLCGSRIPEPLAAMLDVWGHDPASLKEAGIIYA
SEQIRDLTARGVDGIHLYTMNRPCVTRRIWANTKAFFG
>A0A0L1KCR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania citrea LAMA 915|TrEMBL
MSPTMDQMREAQRALEAPLFSGLPGDIDVSFEFFPPKNAAMSETLWQSVETLARLGPRFA
SVTYGAGGSTRERTHQQVVRIQNEARIPAAAHLTCVEATREEVDEVARHYWDEGIRHIVA
LRGDAPDGQSQYAPHPGGYANAVELIAGLKRVADFEISVAAYPEVHPDSPDRQADLDNLK
AKFDAGATRAITQFFFDPQCFFDFRDRAAAAGIDGEIVPGIMPVLSFAAVRRMSGLCGTA
IPPWMEGLFDGLDDRPAARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRAKAGR
>A0A495A0Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria tytonis|TrEMBL
MSAPLLDSHHVRDATVEPPTGTSWLVRRPRRSTLVSFEVFPPRPTADPDTVWRSIDAMAQ
AGPDFFSVTHGHSASGGVSRAALRHLRRTTKTPVMAHFTCGGTDRAGLERSVERLVDDGV
RDLLALRGDPPLGAGEWETPPGGIGRAAELVRLVRDVERRRFGGGFRPGNRPLSVSVACY
PSPARGRDFEADLASLWDKQEAGADYAITQVLYEPEDYARFLERARSEGIHLPVVAGLMP
LTDPRRLRRMTEITGVPVPRHLTEFLTADSAEDLRHRGTAATLSLIDDLLDLGCAGFHLY
TFNRPEAALTILEHLRVRDAAREYRGRSPAA
>A0A7K1V687|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia terrae|TrEMBL
MSFDNVRGYSTPGRVSRTPQVSGTRSVVQQLGPRPDGSVPFSVEFNPPRDAAGEARLWRA
AREFERLHPAFVSMTYGAGGSTRDRTIRITGQLASETTLLTVAHLTAVDHSVAELRSIVG
AYADSGIRNLLVLRGDPPGDVLGEWVKHPEGVEYADELVRMVRELGDFHVGVASFPQGHP
RSGDLDEDTRYLCAKLRAGAEYSITQMFFDPEHYLRLRDRVIACDPVEGAKPIIPELMPI
TSLRTVERAVELSGRDLPAKVMERLRKAAGDGPEENRAAVREVGIEIATEIAETLIAEGA
PCLHFITLNFAKATSEVLANLGYTMSPAPAAVR
>A0A7J9VRF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriales bacterium|TrEMBL
MVLGLSSHWPGGAASIRELLALGDRSFSFEFFPPKDDEGERVLWTSIRELEALHPTFVSV
TYGAGGSTRDRTVRITEAIAGETTLTPVGHLTGVDHSRAELRAVIGSYAAAGVRNLMLIR
GDPPGGPGHPWVRHPDGIDHAVELVEMVRELGDFCVGVGAFPEGHPEAASLEEDARVLAD
KAAVGADFAVTQLFFRASDYFGLLDRLAAIGCDIPVIPGIMPILNLRQVRRMAELSGADV
PADIVRRLESYGDDRAAVRAAGIELATGLCDELLAGGA
>A0A2I0RWR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cercospora zeina|TrEMBL
MDKLTDKIAALPPDATYFSLEFFPPKTQQGFSNLNARLSRLAHSLRPLFVNVTWGAGGST
SVKSLALAEVTQRELGLTTCLHLTCTNMSRKLIDEALEQAKVLGIRNILALRGDPPRSDE
YRDDSLPDAGEDDSNKDFTWAVDLVRYIRRQYGDYFCVGVAGYPEGHADQSHPEHQSIEH
DLPYLVEKTAAGADFIMTQLFYDVDAYQKYEKRLREHESGLFKKIPIIPGLMPVQSYQIL
RRTTKLSHAALPQEILKRLEAVKGDDEAVKRVGVDVLSEIVDTMKHSEFAGPRGFHFYTL
NLEKVVTQILERNDLIPPCTPEAELSLEMQAVAVEETDDFVMVEDAKNQQHRRKSSMANS
NPRNRVILSHARASSTSSNRLSSAYEAFDDEAGVPKDKINSRANTLAISEGEGALGREAT
WDEFPNGRWGDARSPAYGQIDGYGVSLHVSVPEARKLWGEPKSVEDISACFRRHLEGEID
SMPWSEETLQPETLTIKNELLSLINKGWWTVASQPAVNGIRSTDPVFGWGPRNGFIFQKP
FVEFFVPSDEWQKLQSRLIENPQITYFAGNSKHDFVSNDAESVNPVTWGTFTGKEIVTPT
IIEDVSFKAWCEEAFGIWNEWQRIYKSGSESSKLLERIRKDYWLVSVIHHGFLEPGALWN
DFYSVDIEAISGICGSISIACWVVVFSPQIIENFRRSSAEGLSVEFIIIWLLGDIFNILG
AVLQNVLATMLILAIYYTLADIVLLAQYFYYTGFRLRDPKPVKAAAAEDGVATERSPLIT
NGHANGRTSPARRHANAADVEVRARSNSAFRERLASLDYTHSSPAVPIHAHPKIGKDADA
LKPHQPRTLLQSVLFNGTAILLVVLAGIAGYYLTPSTPENKRATPAKEQADSLEFSTWGQ
IFGYICAVLYLGSRVPQLLLNYRRKSTEGLNALFFLFACIGNLTYVCSIFAFNPICSRHR
HGHWRQSQCQPGEAASIYGQYILVNLSWLIGSLGTLFLDFAVFVQFWVYRDNQAPEVDSA
HETLVDPDEDRGREASSR
>A0A239RYW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MCRREKSYDSSSIFDLYYNSSFLILWIISPVMSLLAQYFAQQQFCVLVEYLSARQAQWSV
KTEFAGFPVAMTLADRVHADDDEAPLQVAKQYPQEIEKVIHFSGKARDIQDFEQFLQDAK
TQGQKNLLLLTGDKLKQHCYSHDLEPRTRYLESVNAVMEAKRQGGFHIGVAFNPFKYAEA
EKEAQYLKLHKKMKAGADYVITQLGYDMAALQDAHAFLVQHQYAQKMLVCVMPLTLARAK
FMLKHKVAGIVITPHMLQVLQQEKEQGLSDRVYVRCALQILVCRHLGFAGVYLSACHQPE
EQSLLERYLEEYRHLSFAECERLWNTLWQVQTGTEFHPKLAYYSRPATSSQIIKYQHLHL
MHDALFESKLAKGVGRFIFNFNVWDRSRANQALLKTEHLSKHAVVGCESCGQCRLGETLY
ICPETCPKGLANGPCGGTSLDRCEFGDRECIHSVKARLAKAVGQTKILKEKLIPTVSITV
RGTSSWKNWYVEAAG
>A0A2A5IXQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pumilus|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSLDEIKR
SFREQLYILLNEQPDGLLLETYYDLDEAKAVLQIARKETTLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPLLENSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRNSALSFRNQGARIIGGCCGTTPQHISAMAEAVKDLAPITEKEVKVLKEEMIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKSAGIDALTLADNSLATP
RISNVACGSLLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIREIMAKAGEDKEKQRTEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKEPNAHVNYH
>A0A672ZLF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaeramia orbicularis|TrEMBL
MVNQVPRGDGSWQSFKSDSSGASTSGGDSSKDSSRCSTPVLEADRSDRLRDKMRRRTESG
DRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTTHKITGYLEKAKRLGLKNIMALRGDPVGADWEEEEEGFNYAI
DLVKHIRSEFDDYFDICVAGYPTGHPEAGSYEEDLQHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIQQAVQMCRVLLDSGKVSGLHFYTLNREVATMEVLRQLGLWTEDPRRPLPWAVSAHPK
RRVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSTKDA
LLQMWGDELMNEQSVYEVFTCYITAQPNHRGHKVMCLPWNDEPLAPETNLLKEELEKVNR
RGVLTINSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRV
NYHIVNVHGQNRTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWG
KLYEEESPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQVIDDMFELLDTPPDPLNAT
>K9W9S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allocoleopsis franciscana PCC 7113|TrEMBL
MMSDSLQQTTFRTDIEAMLVESNSHSPVSTQSQFRTAAQSGEFLITAEVAPPKGGDPSHM
IKMAQALKGRVHAVNITDGSRAVLRMSSVAASVILLQHGIEPICQMACRDRNRLALQADL
MGAHALGIRNILALTGDPLKAGDHPDAKGVFDLESVRLLKLIGKLNSGFDANDKPLTDGV
TDLFTGAAVDPQLKSWSGLQRRFERKLEAGAQFFQSQLITDFERLEKFMNEIAAGTNKPI
LAGIFLLKSAKNAQFINKYVPGVHIPETIIDRLAGADEPLQEGVKIAAEQVQLARQLCQG
VHMMAIKREDLIPKILDLAEVQPLKS
>A0A2H2ZEB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma parareesei|TrEMBL
MHIRDLVADTEKSGAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLEKVNDALQKAYKAGCTNILALRGDPPRDQTS
WKAADGNFQYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGAGF
IVTQMFYDADNFIRWVGRVRERGITVPILPGIMPIATYASFLRRAKHMQCRIPPDWMAKL
EPVKNDDVAVREIGKTLVADLCRKLLANGIHHLHFYTMNLAQATRMVLDELNWTPSPERP
LKQPLPWKQSKGFGRRDEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKKWGEPKSVQDIATTFVQYLEKKIETLPWSESALSAEADPIKDDLVA
LNKRGLLTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLMPPYLLEEMIRRLDDFP
NLTYYAVTKNGELKSNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGVDW
AHCFDAGTPSRALIEDIMNNWYLVNIVNNDFRENNTIFALLEGLEVKDLAVPASGTTSAS
GTA
>A0A1F1C7U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC072G04|TrEMBL
MSQHTPSLSFEVFPPNPEVGNAKLLRALANMQELAPHFISVTASNNKYNIKETTVALANY
IQNELSIPTIAHLPAVYLSKEKVADTLHELDEVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFEVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVYQATKALFDHQPNFEGN
>D4DJK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton verrucosum (strain HKI 0517)|TrEMBL
MHIKDKLALAEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMPREKVDDALQSAFKAGCTNILALRGDPPREKEA
WEQTEGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFLDWVKKCRQAGIKVPIIPGIMPISTYAAFIRRTNWVKCAVPKGWMEAL
EPVKNDDAAVKQIGKALVSEMCRKLLENGINHLHFYTMNLAQSTTMVLEELNLKPSTETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSVRDLSDIFVRFLEHKLDRLPWSESAITQESEIIKDDLID
LNNRGFLTINSQPAINGAKSSHPIYGWGPRNGYVYQKAYLELLISPALIDEVVRRIESNA
DLTYHCINKDGELKTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSASRKLIQNTMDTWYLVNIVNNDFHKTHDIFDLFKGLVLKDIDTEVSGTQQTTE
PAENGTHSEARAPKTEKQAVSAK
>I4C7S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1)|TrEMBL
MNTESRLEKVLTSGNFAVTAECGPPKGSDVAALQEKGKHLLNCVDAVNVTDNQTAIVRMS
SVAASAILKNMGHEPVLQMVTRDRNRIALQSDLFGAYALGVRNVLCLTGDHHSFGNQKET
VGVFDLDSIQLLRTVRDMREQGTIIGGEAIQVPPKMFIGAAENPFADPISWRVVRLAKKA
AAGADFIQTQCIFNVDRFAEFMKQAHDRGITEKLYVLAGITPLKTVGMARYMANKVAGME
IPEELISRMAGVPKEKQAEEGIKITVETIQRVREIPGVAGIHLMAIEWEHKVPEILKAAG
LDKRPAA
>A0A419EPY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Abyssubacteria bacterium SURF_17|TrEMBL
MKSGSNLEKVLSAGHTAVTAELGPPMGCNAETVRKKMELLRGTADAFNVTDCQTAVVRMS
SISTSIFLAQAGMEPVMQMTCRDRNRIAIQSDILGAAAHGIKNCLCIAGDHQSFGAKGKL
KGHPGSKNVYDVDSIQLVGILRGLRDDARQQGGDPLDASVPLFIGAAWTPLGDPIEIRTI
RLAKKVNAGADFIQTQAVYDIKRFSEAMQKARDRGLHERVAILAGIIVPKSGGMLAYMNK
SVPGVVVPQELIDRMKAASDQRAEGIKIAVELIQQVLQIEGVRGVHIQAIEWEEAVREVV
GGAGLLPRPTV
>A0A1G0HRP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_42_13|TrEMBL
MKGKKIEFSVELFPTANASGQLQLQNTIERLEALGPRFFSVTFGAAGFSTQHLTTALVSE
LIDSDIAVAPHISCLNLSTQEVDALLKQYHAQGVQRLVVIRGDDPDTNNAEKKARVFPYA
IDLVRYIRSTTGNRFELFVAAYPEFHPEAPACEHEFHYLKEKFLAGADAAITQYFFSGEA
YECYLENCAKLRIHLPIIPGVMPIVQYDRLMRFSNRCGAEIPRWLSKRLEAYQHEPIAFN
QFGIDVVTKFCESVIALGAPSLHFYTLNSANLCEQLIRNLSGHLVSAKRYATTASFV
>A0A258N584|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichales bacterium 35-46-9|TrEMBL
MKLSAEFFPPRTTEGLDKLVEVAEGFRPFNLDYLSVTYGAGGSTQERTLATVKALRARGW
DVAPHLTCVDSERGKIADLLKTYIDLGVHRIVALRGDIPSGMRDLGDFNFAIDLVKFIRD
TTGDHFHIEVAAYPEVHPQAKNWQTDLQHFADKMAAGANAAITQYFFNPDSYCRFVNAAR
ELGVKGDIIPGLMPITNHDQLVRFSDACGAEIPRWLRKRLEAFGDDKAAISELGLEVVGD
IGERVMRGGAPGVHYYAMNSLEPARSLMERLRSFSA
>A0A520DTA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp|TrEMBL
MSDRPRLPLSFEFFPTKTPEGAVKLRAVRQQLYVHKPEFCSVTYGAGGSTHDGTFGAVRE
ILEEGCDAASHFSCIGATKATVRTQLAELKAMGVRRLVALRGDLPSGYGIGGEFHYASDL
VRFIREETGHDFHIEVACYPEVHPQARSPEADMQAYAAKVRAGADSAITQYFFSAEAYFR
FVDDSRKLGPDVAKVPVVPGVMPIISSTQLMRFSDACGAEIPRWIRLRLQSYGDDIASIK
AFGLDVVTDLCERLREGGAPALHFYTMNQSQATLAVLERLG
>G3AM20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1)|TrEMBL
MTTVKEKIQSLKPNEKFISFEFFPPKTDSGFRNLLARLNRMSALNPLFITVTWGAGGSTS
EKSLDLAATCQNDLGLTTVLHLTCTNTNKEIIDDALARAKRNGIRNILALRGDPPRTQEY
WTPNCEFNGAVDLVKYIREQYGDYFCVGVAGYPEGHVDGSDASGQDPKKDMPYLVEKVKA
GADFIITQLFFDVDKFISYEQLLQEYEELKDIPLIPGLMPITTYRVFTRASKLSHASIPR
EILDELEKVSNDDDAVKTLGVEILSDIVKKIDSTIGSKIKGYHFYCLNLEKAVASIVDQS
EVLKPILDMPQVSAEHDDAIASESEDEEQAIPASSTKNGINRRKSSLINDNEVAISPATK
ELISKALLKDRQVVVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPNLKIHT
PAEASLKWGTPETKQDLTQVFTDYLSGKIDVLPWTDTPLSPETALIQEELFELNKKGWFS
LASQPAVNGCKSTDRIFGWGPRNGIIYQKAFVELFIPKSEWESVLLPRIQSSIEKKTITF
YAGDKDGKIQSSLLNEPDARYTKNAVTWGVFPSKEVIQPTIIDYESFRAWNEEAFSLWLQ
WARCYKMSSKSFQLLNSVYTDYVLVSLIHHDFPEESALWDTLLGE
>A0A1V2QG51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix sp. ALI-22-I|TrEMBL
MTSVVERLRGGSPVFSVEFFPARDEAEEGVLWRAIRELEAFDPAFVSITYGAGGSSRDRT
IRTTGRVAQETTLLPMAHLTLVDHSVAELRNVIGWYAAVGVRNILAVRGDPPGNPNGEWV
PHPEGLTYAEELVRLCRELGDFCVGVAASPYGHPRSTDLDEDTKYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAAQGCDTVLLPGLMPLTSARTLVKTVELSGAPVPPSVARRLDPFA
DDPASFRKAGIDLVTEVGQRLLAEGVPGLHFYTLNRSKATREVVARLGLVPARAV
>A0A520CAR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp|TrEMBL
MRIPLSFEFFPTKTPEGAAKLRAVRRQLYATRPEFCSVTYGAGGSTHEGTFAAVREIVEE
GIPAASHFSCIGATRATVRAQLAELHAMGVRRLVALRGDLPSGYGIGGEFHYASDLVTFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFATKARAGADSAITQYFFSAEAYFRFVDD
ARRLGVDIPIVPGVMPITSSTQLMRFSDACGAEIPRWIRLRLNGFGDDVESIKSFGLDVV
AALCERLRDGGAPSLHFYTMNQAAAPLAVLDRLGWGT
>A0A2A4VXV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilaceae bacterium|TrEMBL
MKNIALSFEFFPPKTEKGIANLRETRNKLATFNPEFFSVTFGAGGSTRDRTMDAVLEIQE
EGYQAAPHISCISSSEEEIVALLNAYKNKGIKRLVVLRGDVPSGEVSTGDFKYAVDLVSF
IRQETGDWFHIEVAAYPEFHPESSSPSSDVANFKKKIDAGANSAITQYFYNADAYFQFLE
TCYKAGIRVPIAPGIMPIYNYTQLARFSGICGAEIPRWLRLRLEAYGDDLPSLRAFGIDV
ISELCEKLSSAGVPSFHFYTLNQAGAISKIITNANLASK
>A0A1M2YME8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. 63-7|TrEMBL
MSHSLLRSADLAKLRFSFEFFPPKSEEMEGQLWATIDDLAGWRPEFVSVTYGAGGSTRAP
TLSTVRRLLAETALPTASHFTCVGASRDEVHQVVEDFRAAGVRHFVALRGDPAGGVGAAY
QPHPGGYANAAELVAGLRSIDDFEISVSAYPEKHPESRDTAADIDMLKRKVDNGANRALT
QFFFDNDVFERYLERVRAAGITIPIVPGIMPIQNLTQLKRFAGACGTTVPVRLDERFEGL
DDKPAERAAVAADVAAEQMADLVRRGIHEFHVYSMNRAPLVNETFARLGLTRKVAETTGA
AA
>A0A7S1PUZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alexandrium catenella|TrEMBL
GFTHAVDLVRYIKENFGDHFCIGVAGYPEGHPEAESKDKDLEHLREKVEAGADLIVTQHF
YDNSDFFAYTDKVKKAGISVPVVAGVMPIQSYQGFTRMRSVLKSKAPSSLVEALEAVKDD
EQKVADLGVDQCVRACRELMERGVAGFHFYTMNREMPTARILCELGLAGDGARVP
>A0A7Z2QC63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. N1-1|TrEMBL
MSLLEDLEHKILIGDGAMGTLLYSYGIDQCFEALNLSHPDQVLNVHQAYVHAGSDVIQTN
TYGANYSKLSRYGLEDLVKEINTEGVKLARKAATDSTYVLGTIGGIRGINTRSTPLDEIK
RSFREQLNWLLLEGVDGLLLETYYDLEEIITVLEIARKETDLPLIAQVSMHEPGILQDGT
SLAAALKQLENAGASVTGVNCRLGPYHMIQSLEQVPLSNRFLSAYPNASLPDYEEGRLVY
PTAPDYFKQSAEALRQQGVRLIGGCCGTTPEHIAAAASALKGLNPIVTKEVTVNEKEARI
IDFEEERLPHLHEIARKQRSVIVELDPPKKLSIDKYLEGTKALQEVGVDAITLADNSLAS
PRICNTAMASTIKAQHNVRPLVHVACRDRNLIGLQSHLMGLHTLGINQVLAVTGDPTKIG
DFPGATSVYDVSSFDLIRLMKQFNQGRSYSGKSLGIKTSFSIAAAFNPNVRHLDRAVERL
EKKQQCGADYFISQPIYNEEQLLEVYEATKHLTCPIYIGIMPLTSYRNAEFLHNEVPGIK
LSDSIRNRMLRATDSTQSGEEGLAIAKSLIDAAFDLFNGIYLITPFLRYELTVELTRYIN
EKTRLEEERKNRNGLHLI
>A0A828W5M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides ovatus CL03T12C18|TrEMBL
MKVIDLINNSKGTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTASPFSYGVACYP
EKHEESPNIETDLYWLKKKVETGAEYAVTQLFYDNKKYFDFVEQAKAAGINIPIIPGIKP
FKKISQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGVEWCVAQCKELMEHGVPSIHF
YSIGAVDSIKEIAKIIY
>A0A396S3R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus yapensis|TrEMBL
MGLLEALQSKVLTADGAMGTLLYAYGLEYCHEEMNIVRPELIEKIHIEYISAGADVIQTN
TYGANAIKLARYGLEAKVKEINEAAVSIAKKAVGNGDQFILGSIGGTRGVRKSDATLEEI
LHAIKEQAVVLIEGGVDGLLLETYFDFEELTETVKMLRAETNLPIIAQVSMHDPGVLQNG
MKLNDALQQLQAIGADIVGVNCRLGPYHTIQAFEGVELPEKAFLSAYPNASLLDIEEGRV
IYESEVDYFARAAVQLRNQGVRLIGGCCGTTPKHIEAAKKLLGQLNPIEIKEAKQPKEIL
IQEPDPREIEPLHEKVKRERSVIVELDTPRHLEIESFVEGAKTLYNEGADIIMMADNSLA
SPRISNVAMGSILKLQHGIRVMPHITCRDRNLIGLQSHIMGLNALGLHDILTVTGDPTKV
GDFPGATSVYDVSSLELISLIKQLNEGISFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKIEEIHEATKHLETPIYIGIMPLTSFRSAEFLHHEVPGI
KLSDEALERMQACEGDKQKESAEGVAIAKELLDTAAKYFNGIYLITPFLRYDLTIQLMQY
IKQLDVQNKGVKANV
>A0A5C4JZY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. BB-1|TrEMBL
MMFPIRIEIIPSEGIIEQVQALVPRTTTLSVTCLPHHGIERTMRTAVEAADLGYTVVPHL
AARSIRSRAELTEIIRGCNAGGIGEVFVIGGDRKQAAGTYDSALPVLEDIAQYTGGTMRA
GVAGYPEGHPLASPLDLLDALLAKQHLASHVVTQMCFDAGKIHDYAALLRREGVRLPLWA
GVAGSVPRTKLVALATQIGVGSSLKFLSRKGPLARKLLSGDRYSPGSLITGLETQPDNIA
GIHLYSFNSLASAQDYGVHTAPEQASPSAALQPALIRGAARDH
>A0A4R7MBB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 846.5|TrEMBL
MALGTSSVRHDSKPSIRELLAAGNCSYSFEFMPPRSAEAEVGLWKAIRQLEGLAPTFVSV
TYGAGGSTRGRTINITGRITQETTLTPVAHLTAVDHSVAELRNILGHYADQGVRNILALR
GDPPGDPLGEWVKHPQGPEYASDLVQLIKESGDFCVGVAAFPEMHPRSSDWDEDVRHFVA
KCRAGADYAITQMFFDVDDYLRFRDRVAAAGCETPIIPEIMPVTSVRSLRRIPTLSNAVI
PQHFADRLLAAEADPRAVRAIGIDYATEMCRRLIAEGTPGLHFMTMNFSTVTMEIYQNLG
LDRRG
>A0A5C5RC16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tsukamurella asaccharolytica|TrEMBL
MSEQSRTVLDRLDAVRAEGRMPFSVEFMPPRDEEGEARLWRAVRTFERMDPAFVSMTYGA
GGSTRDRTVRVTGEIAETTTLLPVAHLTAVNHSISELRALMGSYADQDVRNVLVLRGDPP
GDPLGKWVRHPAGLKYASEVVELVRELGDFHVGVAAFPEGHHRSPDLDTDVRYFANKLRA
GADYSITQMFFDVDDYLRLRDAVAAADPEQGAKPLIPGIMPITSLKSVVRMAELSNAKIP
EAMRAELRAAAGDGPEENRAAVRAVGIDIATRMGERLIAEGAPALHFCTLNFAKATSEVL
ENLGMLPVGV
>A0A557QCG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denitromonas halophilus|TrEMBL
MNPTPFSIEFFPPQTPAGVDKLRGTRAQLAQLQPEFFSVTYGAGGSTQERTFETVFEIQA
EGLAAAPHLSCVGATGDSIRDILKRYQDKGIRRIVALRGDLPSGAVEAGELRYANELVEF
IRRETGDWFSIEVAAYPEYHPQARTAQSDLAAFKRKVDAGANSAITQYFYNLDAYLHFRD
ECVAMGIEIPIVPGIMPIVSFSKLARFSDACGAEIPRWMRRKFESYGDDTDSIKAFGLDV
VTDLTARLIEESAPGLHFYCMNMAGPTSTIVERLGLKA
>A0A5C4R6J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus haeundaensis|TrEMBL
MTTPNVSFEFFPPKTLEASFKLWETAKVLAPLAPDFVSVTYGAGGTTRKLTHEAVTTINR
QFGLQVAAHLTCVEATRAETMEIVQSYADAGITQIVALRGDAPKGADRFTPHDDGFANSV
ELIEAIAARGDMTIRCGAYPEPHPDSADGDADVTWLKRKIEAGATSAITQFFFEPETFFR
FRDKCVAAGIDAPIIPGLLPVQSWAGTKRFAATCNTTVPDWAEEAFQLAALDGPDAQRAL
ATDLSVDLCEKLIAGGVDQLHFYTLNRPELTRDVCAALGVRPKAGLEAVA
>A0A2I1KJ90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces naeslundii|TrEMBL
MPTVSLELFPPRPGKAASATWGRIDRLLATGPDFVSVTYRPTFVTEPVPGTGRRSGADQE
CLPRVRVVQEEANPSEGVLAHVLESSTIPLMAHLTCIGYCKQEAVDIVTRFLRMGVRRFL
ALRGDPPAGARADEVAGELRHADDLVRVIREVEADFFGDGKRHVTIAVAAYPATNDHIEA
IEVLAAKQAAGADLAITQVFYDPADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEA
LTGVKVPDALRSSLGSASGATLVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVI
SHLRLGGILAGAAPDREVRDAVDRGYLQATPGRGPSFLRSGSPGAAASPRHPVQPHNTIT
KENA
>A0A1J4YRU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium CG1_02_53_45|TrEMBL
MKLSHILNTASKPLFSCEFFPPRTDKGEENLWSCLKELQTINPAYISVTYGAGGTTQDRT
KGIVTRIKDETGLSPVAHLTCVGANKDELAALLADYRGAGIENILALRGDAPEGMDRFEA
ATGGFSYATDLISFLREQGDFSIACATYPEGHPESKGGVADDIRYLKMKQDNGADCAITQ
YFFENETFFRFRDACDKAGITLPIIPGIMPVGNFEQIVRFSSMCGAEIPAWMHEKMTPIQ
HDPDAVKALGIELAARQCRELLQSDAPGLHMYTLNKAEATIAIHRQIKDLL
>A0A0V0IKU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solanum chacoense|TrEMBL
MRAKYGDYFGITVAGYPEAHPDVIPANGIATKEIYENDLAYLKKKVDAGADVIVTQLFYD
TDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKIPEEIMAALEPIKDNEE
AVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALAILMNLGLIEESKISRPLPWRRP
ANVFRVKEDVRPIFWANRPKSYISRTTGWDEYPHGRWSNAQNPSYGALTDYQFMRARSRD
KKLQEEWAVALNSVEDIYEKFKDYCLGKLRSCPWSELDGLQPETKIINEKLGQVNKKGFL
TINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLELFCSQEKLNALVEKCKSFPYLTYMAV
NKEGNWISNVNQTDVNAVTWGVFPAKEIIQPTVVDPASFMVWKDEAFEIWSRGWAQLYPE
TDPSRKLLEQVQNSYFLVSLVDNDYINGDLFSIFKDI
>A0A5C4K338|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. BB-1|TrEMBL
MSPPSLIETHPNLSDAAPVALSYELFPPRSPAAAETLWTTIRELETTAPDYVSVTYGASG
SNRDTAVDLINRLLLETTLRPLAHLTCVGNTPQELAGIIGELLDTGVRGILALRGDLPKD
GGEPAAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLLTRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAPELLERMAAADSDLERMRIGVSATVDLANAALEAGAPGIHLYTFNEHQSALDVLDKLA
LPRRTRSSRSEAVAGQLAS
>A5I291|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIKNILALRGDIPKDKDIIGE
YNYAFELIEKIKASNNFGISGACYPEGHIECKSLDQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQEKSINVPIQAGIMPVVNKKQIERIVKISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDIAV
>A0A6A4HP94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gymnopus androsaceus JB14|TrEMBL
MKVTQKIAQCEKESKTWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDVTWNAGGRTS
ELTSEMVKTCQGLIGVETCMHLTCTNMPKEKVDIALREAKVSGCRNVLALRGDPPVGKDE
WEAVEGGFVHGIDLVRHIRREYGDYFDIAVAGFPQHQTLPSDERDLEMKWLKEKIDAGVN
FIFTQMFYDVDIFIEWVKSVRAVGITVPIVPGIAPIQNWNGFQRASSLAKIVIPQNFLDA
LEPHKANDEKVREIGTKLVAEMCRKILNANLGIHGLHFYTMNLEKGTKMLLEELNLVPRM
ETVKPLPWRQSLTPTRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVSIKQSKEDALKLWGEPSTFAQVAALFAQFCLGKLEALPWSDQKPSVETSIIQEQLA
RMNSLGFLTINSQPAVNGAKSNDKVFGWGPRNGYVYQKAYLEFFVNPGLLTLLLSHIERD
SNITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGQQ
WARIYDADSPSAKIISELMDTCYLVNVVHNDFHDSNAIFKPFFQAGEEYAASQANALNGH
>A0A1E7HR56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium C00003094|TrEMBL
MVQSSRGNNRFLQRLAAGLIIGDGAMGTLLYNRGIPLGHSFEALNLSRPELVEAVHRDYT
AAGAQLLESNTFAANRLALGPLGLDGRVAEINAAGVRLARKAAGIDRLVAGAVGPLPPAK
GQTAELSLVEQRSLFSEQMTALAEAGADLFILETFAVIEELELALQVAADLDLPAVAQMA
FFEEGRTRHGMTAEEVARRLSAVGAAVVGANCGSGPRELLTVLQRMATVTDRPLSGFANS
GFPQYANGRYIYLATPDYFATMGREMVAAGACLVGGCCGTTPEHIQALSMSLKDLHPIER
PAPIIVVTEQPVVAEPALAKRTFLADWGRRPVVTVELGPPKGLDCRKVLRGAEALAKAGA
DAISLTENPLARIRMGNIALASQIQQQADIEVIIHITGRDRNLIGLHSELLGAHLLGIRN
VLAITGDPVAIGGEAGASSVFDLNSVGILQLLSSLNKGTTLLGAELGGTTQMLAGAAFNP
NVADMSGQIRRMEKKIEAGARFVETQPVYSAEVMLEMLERLAPLNIPVLIGLMPLVSERN
AEFLHNEVPGISLPDEVRRRMAGTSGPAGVSAGMTIARELIDAGRQAAGGYTLMPPFGKV
ELALELLRYIRG
>A0A5C1WFG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labrys sp. KNU-23|TrEMBL
MAGHALPSHGGIRVSFEFFPPKNAEMEAALWEAIERLAPLDPLFASVTYGAGGTTRERTH
GTVARMVQETDIRPAAHLTCVGATREAIDEVIRGYAEAGVRHIVALRGDPPAGVGARYEP
HPGGYANSADLVAGIKAQGDFEVSVSAYPEKHPESPSLAFDIDILKAKVDAGATRAITQF
FFDNEHYLRFVDRVREAGIDIPIVPGIVPVQNFNQVRNFAERCGTDVPQRLADRFEGLDN
DVATRKLVAAAVAAEQVFDLVDRGVSDFHFYTMNKADLVYAICHLLGLRPKVEKAAA
>J7EQB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nicotiana tomentosiformis|TrEMBL
MKVIEKIQEAAKDENRVVFSFEFFPPKTEDGVENLFERMERMVAHNPSFCDITWGAGGPT
ADLTLEISKRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKINGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDVIPANGIATQEIYENDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQLGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPEEIMAVLEPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTLGWDEYPHGRWGNAQN
PSYGALTDYQFMRARSRDKKLQEEWAVALNSVDDIYERFKDYCLGKLRSCPWSELDGLQP
ETKIINEKLGHINTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSGEKL
NTLVEKCKAFPYLTYMAINKEGNWISNISQTDVNAVTWGAFPAKEIVQPTVVDPASFMVW
KDEAFEIWSRGWAQLYPETDPSRKLLEQVQNSYYLVSLVDNDYINGDLFSIFKDI
>A0A558GTR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio atlanticus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVKLLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A1Q5L4J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TSRI0107|TrEMBL
MNPGPTAARAVRTTLLEDFSLEMTGKDVPHLEEARHLIPRGTRINVTFLGNEDLGMRLDA
ARAVKRLGFLPVPHLSARRIPSRAALEEFLEALRADGVGEHLFVVGGDPARPEGPYEDAL
SVIRTGLLERYGVRHVGVSGYPEGHPAIADGVLWSALTDKHAALAERRLGGHVITQFGFD
ADPVLAWVAETRARGVDLPIRVGVPGPAGVRRLMSYATRFGVGTSASIARKYGFSLTNLM
GTAGPDRFLRALGEGYDPAVHGDLKVHFYTFGGLRATSEWAARFSREDGASVTML
>A0A062SEU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 25977_9|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A089WPG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas cremoricolorata|TrEMBL
MSQERRYSFEFFPTKTEAGHDKLISVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKIPAAPHLSCVGDTKAELRALIGEYKDAGIKRIVALRGDLPSGMGMASGELRHASDL
VQFIREETGDHFHIEVAAYPEMHPQAQNFESDLKNFATKVKAGADSAITQYFFNPDSYFY
FVERVQKLGVDIPLVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDAASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLQLPR
>A0A3A5MFN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium melibiosiphilum|TrEMBL
MNSTDPACTDGIAGVPSRRTARVPFSFELYPPKTDAGATALHAVIDHLAASGPDFISVTY
GANGSSRGSSLDVLKYILHETRVDPMAHLTCVGSSHAEASSLIREFLDAGVHSFLALRGD
PPQGTREGDSFLGDLGSAAELVQLIHRVQAEKVPYRETVIPGLPRARRLKTTRDKVRIGV
AAFPNGHPQSRSTSQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAEEAGVTFPILP
GIMPVTSPNRLRRILELSGEELPAELSIQLEIEPTEAGQREIGIAHAVRLGQELLAGGAP
GLHLYAFNQHDTVLSVLEGCGALPNGRTPTLSAHPPTDHTFARAAAHPVKESV
>A0A1C0PAJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter freundii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A842DQZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLKDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKSLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKEAFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVAEQIISQN
>A0A8H6VQ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudocercospora fuligena|TrEMBL
MHISEKLAAAHAKGQHTCSFEYFPPKTAQGVQNLYDRMDMMHGLGPAFIDITWGAGGRHS
SLTCEMVKVAQSAYGLETCMHLTCTDMERSKIDNALEEAYKAGCTNILALRGDPPREQEK
WEAKDGNFRYALDLIKYIKKTYSDHFDIGVAGYPEGVDDTTNADEHIKYLKEKVDAGGTF
IVTQMCYDADIFIEWVKKVRAAGIPESVPIIPGIMPISTYAAFLRRANWSKARIPPEWLE
VLEPIKNDDSAVRDAGCDLIVEFCRRLMNSGIMHMHFYTMNLAAAVRMVLEKLDLTPPAE
SPHPDIKPLPWRQSLGLNRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
GLDEYGIGLKGTNENNRKIWGEPKTIKDVVGLFVGYMRGKVESLPWSEAPINEEANTLVD
DLVALNSRGLLTINSQPAVDGVKSSHPVYGWGPRNGYVYQKQYLEVLVSPDLIGTVIQRM
EQDPDITYYAVNCNGELKTNAPTDGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYH
LGVEWSKCYEEGSESRKLIKEITQSWFLVNIVHNDFRQQQGIFPIFDGLKVPGLDEVPYT
NGVTNGVHGVNGVNGHAHNHEKPETNGVPDGNNVVNGAEKASSNSTLKN
>A0A6I1QA92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. B1Z05|TrEMBL
MGYTHASHIDALNQNVAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKALKPKFVSVTY
GANSGERDRTHSIIKEIKSQTNLIAAPHLTCIDASRDELITIADDYWKNGIESIVALRGD
IPPNGGTPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPMTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRP
>A0A850S190|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariprofundus sp. NF|TrEMBL
MKLSEILGAATKPLFSCEFFPPKTDKGEENLWNCLRELQTINPAYASVTYGAGGTTQDRT
KGIVTRIKDETGLSAVAHLTCVGASRDQLADLLADYRAAGIQNILALRGDAPEGMDHFQA
TEGGFSHATDLIAFLREQGDFSIACATYPEGHPESKGGVADDIRYLKMKQDNGADCAITQ
YFFDNEAFFRFRDSCDKAGITMPIIPGIMPIGNFDQIVRFSSMCGTSIPAWLHEKMDPVR
EDLDAVAKLGIELAASQCRELLEQGAPGLHFYTLNKSAATIAIHGKISDYL
>A0A1G9IVG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sarcina sp. DSM 11001|TrEMBL
MKIIDILNQKKVTLSFEVFPPKTEEALLSVEKATEIIAALRPDFMSVTYGAGGGTSKHTT
RIAADLEKKYGTNVLAHLTCVSSTKETVRKMIDTYKEHGIRNIMALRGDIPAEGRSVFDY
NYASELIYDIKSHDGDFCIGGACYPEGHVESASQAEDIRHLKEKVDAGCDFLTTQMFFDN
STMYSFLYRIREIGIEVPVVAGIMPITTKAQVKRTVALSGATIPHRFRAMVDRFGDDPQK
MKQAGIVYAAEQIVDLIANDVSHIHVYTMNKPEIAAGIQSSLSALWG
>A0A413I4F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. OF03-15BH|TrEMBL
MTKLTRLSEMMKEKQLLSFELFPPKTDKGMNNLPETIKKLCEFHPEYISCTYGAGGGNVG
RNREVCQEIIKAGTVPVTHFTVIKNTKEGIKEQLQNYLADGVDHMLALRGDIPRGETTTC
GDFNYATDLVAFVRKEFGDKFEIAVAGSPEGHIACRSLEADIAVLKQKQDNGADYIMTQL
CWDMEQFKYWLDAIDKAGVTMPVDVGIMPILDQAATINMALSRNGCVMPRELSRLISKYW
IFPNPFDKEPFDDALEQKKADFKKAGIEYTIRQIDEYRALGINGIHLYALNKWKDVAEII
NASGMRTMI
>A0A507DN00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chytriomyces confervae|TrEMBL
MYTLGPEFVDVTWGAGGAQSELTLQICTTAQSVAGLETCMHLTCTNMPREKIDWALKNAK
QAGIQNILALRGDPPHGHSDWKAIDTGFAYAIDLVKYIREQYGDYFCIGVAGYPEGHIEN
SDRQSDFDHFVEKCKLADYVVTQLFYDCDLYLEWVKRVRAAGVQIPILPGIMPIQMYGGF
KRMTTLSKTSVPKEVDAALEPIKDDDKAVKEYGVKLAIEMCNKLRAAGQKGFHFYCMNLE
KSVRLILEGLEFVAPVEVAKPLPWNPSLAQNRKNETVRPIFWRNRTRSYVLRTEAWDDFP
NGRWGDSRSPAYGDFDGYGVSLKFTPEEATKIWGTPSKIGDIHELFSQFCKGNLAGLPWC
DKMAPESEGIQNPLSDVNLKGFLTINSQPAVDGAPSNDARYGWGPKNGFVYQKAYIEFFV
SPAALDKLIKKLSVDPFITYYAVNKEGDMKTNVQSDTPNAVTWGVFPGQEIVQPTVVDGT
SFMAWKDEAFELWMQWARVYPASSPSTKLIQGISDSWFLMNVVHNNYRDAGAIWEIFD
>A0A416ZLM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. AM47-4|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>W2UEI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium MOLA455|TrEMBL
MFEDEPLAGENLPMLPGHDSPGRFERVLRAGHFAVTAEIAPPDSADPQDVFDRAAQFDGY
VDAINATDGSGANCHMSSVGMCALLTRRGYSMIMQISCRDKNRIAIQGDVLGASAMGVSN
ILCLTGDGVQSGDHPEAKPVFDMDCMTSLQMLKGMRDQGQFLSGRKIASPPPVFLGAAAN
PFAPPFDYRPLRLAKKVAAGAQFIQTQYCFDIDMLKTYMAKVRDLGLHKKVFILPGVGPL
ASAKSAEWIRNNVAGVHIPDGIIKRLAGAQDQKQEGVNICIDMISEIRQIEGVSGVHIMA
YRQEERIAEIVEKTQVLGGRTPWRPQQ
>A0A1Y1Q7V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiothrix lacustris|TrEMBL
MTDDHQHDHHHDDLIFSFEFFPPKTDKGADNLRAVRTQLAALQPRFFSVTYGAGGSTQAN
TLNTVLEIQRDSGIEAAPHLSCVGSSAEQIREILDTYRSNGIKHIVALRGDLPSGSRDLG
QFRYANELVEFIRKETGDHFNIEVAAYPEMHPQAPNLKVDIDNFVRKVQAGANSAITQYF
FNADAYWHFVDECVKKGVEIPIVPGIMPITNYSQLARFSDMCGAEIPRWLHKQLETYADD
VESIAKFGEEFISLLCENLLETGAPGLHFYTMNRVEPTMSIWKNIGLAD
>W2CFI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella sp. oral taxon BU063 isolate Cell 5|TrEMBL
MERVIDLINKSRGTAFSFEILPPLKGNSIQSVYRVIDKLRDFDPKYINITSHHSEAIEVR
GTDGMVRTVNLRKRPGSVAIASAIQNRYGIAAVPHLVCKGFTKDETEYGLIDLNFLGVNN
LLLLRGDVKRLHEPDNAELYHDHATDLQVQVNNFNRGIALDGSPITDIETPFSYGMACYP
EMHEDALSMDDDIRYAKLKVEQGAEYLVTQMFFDNAKYYAFVDRMRAEGVTVPIIPGIKP
IVLRDQLEVIPRIFHCTFPPEFAAALGRCRTDEEAKEVGVEWCTAQCRDLVAHGVPSIHF
YTLMASDSICRVAKEIY
>A0A7M1B397|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas sediminis|TrEMBL
MFDTLIHKLKNDRYITLETTPGHSATFTPTIDKIETLGLADLVDGFSTTDNPLAKLKYNA
LFAAKLLQERFKKPVIATMSMRDRNKIALQSDLLGANEFDIRAILALTGDPATISDQPNT
KGVFEGDSSLLLDIIAALNSGMDYAAKPFNVTPKQIHPFAVVNSYAKNPKTLQKKMQKKI
KHGAVGIITQPVYDVENAKQLLELKEKANKECCRENKNAELILGVFPITKLRTAQFLSSH
VPGINVPPCWIDKLREANTKGAEEEYKVGFELSKKLFEELKQLHPKIHLMTANQFQIAKD
ILV
>A0A7Y4YVK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp|TrEMBL
MNSTSESRRAHASPLFAGLEGDIGVSFEFFPPKTERMAETLWDAVNMLEPLRPRFVSVTY
GAGGSTRERTHATVERIVRETGIPAAAHLTCVDASRAEIDEVARAYWEIGVRHIVALRGD
PPTAGAAFEPRADGYASAADLVAGLKTIAPFEISVGAYPEVHPEAASAGADLDNLKRKLD
AGADRAITQFFFEPDTYFRFRDAAAAAGVDAELVPGIMPVSNFAAVQRMSGMTGTAVPPW
LAHLFEGLDDLPAARQLVAATVVAEMCRRLYAGGVRQFHFYTLNRAELSYAICHLLGVRP
R
>A0A1X7IJM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus aquistagni|TrEMBL
MSNGVVTLREAMRQGVVVGDGAMGTYLYEQGFPVGISYEDLNLTAPDTIRNIHREYVAAG
AKLIETNTFTANREKLIRHGLEGKVKEINRAGVRLAREAADGQAYVVGALGSIRAGKREN
IDTSQVMRDYEEQLSALLEEGVDGLMFETFYDLEEMRLALHIARKLDQQVPIICQFAVED
SDRTKDGVRLTESFRILHLEGADVVGLNCRMGPNGLLRAMEQVDGRDRFPLSAFPNAGMP
DYVDGRYNFVASAEYMADSAVRFAKLGARIVGGCCGTTPHHIRVIAEAIEALDPLELPQA
PEIVALTLTGQSQYAPLLVTESEASELEVDESIPQAWHASGHDNLDRQESIIDLVERRHT
VIVELDPPRDLSIQKFMEGARALKQCGADALTLADNSMAVTRMSNMALGHLVHEETGIRP
LIHIACRDRNLLGTQSHMMGLDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEIIRMI
KQLNRGMAFSGKPLKQKANFVVGAAFNPNVKYLEKAVERLHRKVEAGADYIMTQPVYDAA
LIERMAELTRDIPIPIFVGIMPLASERNAEYLHNEVPGIQLSQDVRARMKGLEGEAGRRE
GVEIGKELLDAAMKHFNGIYLITPFMFYQMTAELTSYVWEKAERKQDPLFRLT
>A0A436GCY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.16.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A1T3FJQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia ursingii|TrEMBL
MKVTEHIAQSKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGEKYFEPTKGGNRYASDLVTQINDLGKGKFLHGEISGNDLNNSFCIGVAG
YPEKHLEAPSMQYDLKMLKQKVELGADYVVTQMFLDNQKYFEFVKLAREAGIDVPIIPGI
KPLAVKKHLQLLPQVFKIDLPEDLVNAVSQCKNNEAVKQVGIEWCVQQCKELLDFGVPAL
HFYTMGKSDNIQKIVSEFF
>A0A503XGS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-3-2|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVGRILKETSLTPAAHMTCVDAPRPEVDAVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEVA
GSAAA
>I9V1C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis CL05T12C13|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A2T0FCZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wickerhamiella sorbophila|TrEMBL
MTKTVTELVGSLSADEKYFCCEFFPPKTEQGVENLIGRCRRLVDLGALFVSVTWATGGAS
AEQTLQLATRFQREIGVPTVLHLTCTNMDREILDHALATAKAAGIRNVLALRGDPPRAEY
KQQSELHCAKDLVAYIRKEYGDYFCIGVAGYAEGHADGAVSEQSVEKDMPFLVEKVQAGA
DFIITQLFYDAEKFIAYEKQCREHPSGVLNSMPIIPGLMPINSYPSLLRSAKLSSANIPP
CVLQHFDHIDTKDDVQVKAAGVKIICDILQKLHESGTQGVHFYTLNLEKSVAEIVTKCNM
VHMLRNEREELPSSVESLATWDDFTNGRYSDPRSAAFGEIDGYGPVIHGADNDSPNEMWG
KPTKSEDISRMFVGHITNEIKVIPFSDQPLNAETSLIQEELIALNEKGFWTLSSQPSVSG
AKSTDRIFGWGPPDGKVYQKAFVEFLCSSENWNKLKTKLGNESMTYFAANEKDDVESNAP
KEPTAVTWGVWGERTAQSTFLTLESFTSWRDEAFDVLRQWQRLYPSSSESFKLLDQEASD
RYLVTVAAHDMGDGLWEFLLN
>B5VTD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae (strain AWRI1631)|TrEMBL
MSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKT
LALASLAQQTLNIPVCMHLTCTNTDKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVE
AGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
AILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETVANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPFKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWET
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKA
WRDEAFSIWSEWAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETDELWEMLLDQA
>A0A0K9I616|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocarbo indianensis|TrEMBL
MALTDTLKAKQFAIIAEMETPKGVDVSDFVANARHLKGRVTAVLVPDMGYAVMRLSALAG
AVLLKEQGLEPIVQFSCRDRNRLALQSDLLGAHILGLPAVMAVAGEPVEMGDNLEAKPVN
DLDPKGFIAAAAALMSGKDLGAKPLKGAPSFCLGARIDSWQDQAEAAQRIGEAKAAVDKG
AQFLVSPPVFDLDAFGGFLEKAGDLGAPVVGSVLLLKSVGMARYLNQNLKGVEVSEDLIR
RIRTASDRPAECVKIAAETVKGLKKICGGALLVTTGWENRLPEILDEAGL
>A0A6J2W7N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chanos chanos|TrEMBL
MVNQGEDVCWQSSKSDSSGASNSGESSKESSRCSTPVLDADRKDRLRDKMRRRIEAGDHW
FSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCQQTKEKITAHLSKAKRLGLKNIMALRGDPVGEDWEDEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVEAGADFIITQLFFRAETFLKF
VRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIKQVIEPIKENDAAIRNYGI
QQAVEMCKELLTSGDVPGLHFYTLNREVATMEVLRQLGLWVEDPRRPLPWAISAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSASPAFGELNDYYLFYLTSKCSKEALLQ
MWGEELTSEQSVFEVFTNYITAQPNSNGHKVMCLPWNDDPLAPETNLLKDQLEKVNRRGV
LTINSQPNINGKPSSDPVVGWGPPGGYVFQKAYLEFFTSSENVTALLTVLKKYEPRVNYH
IVNVQGKNRTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWQVIEDMFEVLDAPPETLDQGNE
>A0A4D9CPC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nannochloropsis salina CCMP1776|TrEMBL
MSALATTEPVEVMEDDRIGELLEQRKGHPTPWFSFEFFPPKTPEGVEKLYERLAEMAPYN
PLFVDFTWGAGGSTAELTLELTIEARRRFGLIANMHLTCTNMPTEKVVDALKSAKDVGIT
NILALRGDPPVGQERWEPIEGGFSSALDLVAYIRKHHDTFFSVGVAGYPEGHPNRIQQVD
SLEGLSKAELGRVAVERAEDGTVTGYYVCRDNDFVQEIDYLKAKVDAGADFVITQMFFDA
EVYVAFVKTCRSAGITVPILPGIMCFNTLQGFKRMVAFCRTRVPEKLWMDMMALSKSDDD
EVRRYGIDFGVRLGQELLRAGSSGLHFYCLNLSRVALGIVSGLGLGSQSVDATYTNEKVE
FETEKAMNGSDKVKSKEKALSNHDHVGAVASS
>A0A7V3VSM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesoaciditoga lauensis|TrEMBL
MKVIDAVKEKQILSLEIVPPDRGQDIDEIFSTIDELMNFSPSFINVTRHAPEVEYLEIED
QIMKVQKVKRPGNVGLSAAIKNRYNIDVVPHVLCTGMNKFQIEDMLIDFKYLEIENLFVI
RGEMENKKALIFEKDGYTHANELVEQISKMNKGIYTYPVDNAKPTDFCIGVAGYPEKHYE
ALNLNDDLKNLKKKVDAGASYIITQMCFDFDVYKTFVEKAKEMGINVPIIPGIKPLVQAK
SMFKIPSAFFVSIPSDFVISMQEARTPKEEFEIGTGYMAKLVEKLLDYKVPGIHLFTMGK
GKSTKALLERIFRKR
>A0A8E0LWT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae PCS8106|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>R6RU66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium siraeum CAG:80|TrEMBL
MKIKDLYTPGRTVFSLEVFPPNKNFPIETVYDAIEGLAAINPAYISVTYGAGGNRANRST
CEIASHIKEKYGIEAMAHLTCINSTRDDVDFMLDDFAANGIENILALRGDNKPDEEPKND
FPHASDLTAYIASKGNFDIAGACYPETHVDAESAEEDIKNLKIKVDAGASHLVSQLFFDN
SCYYDFEKRARAAGIDVPIAAGIMPVTNKKQIERMVTLCGASLPSKFVKMMQKYENDPEA
LRSAGIAYAIDQIVDLISNDVQGIHLYAMNNPAVASRIYNGIKDLL
>A0A1F6UL16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Muproteobacteria bacterium RBG_19FT_COMBO_61_10|TrEMBL
MDSQKNHTRSFSFEFFPPKTEEGRANLRTTTQQLAQLKPRFFSVTFGAGGSTRDGTYDAV
HDIQAQGQTAAPHLSCVGSTRQNVRDILNGYKALGIRHLVALRGDLPSGTVSPGELRHAN
ELVEFIRAETGDWFHIEVAAYPEMHPQAKNMEQDLLNFKRKVDAGADSAMTQYFYNADAY
FRFVDDCEALGIRIPIVPGVMPITNYKQLARFSDACGAEIPRWIRKRLEGYGDDLDAIRA
FGLEVTTDLCDRLLSAGSPGLHFYTMNRAGPTALVWERLGL
>A0A357BLP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MNSMHKITDIFQHKKRTYSLELFPAKTEQGHQKLLTTIEELCRLKPDFISCTYGAGGGSR
QRTFEIVQHIEQTHRVTGLAHLTCVLHTKTELKNILEDIKSRGIRNILALRGDTPGDHPD
WQPTEENFKYSSELCAFIRANFNGYFGIGVAGFPEGHVLCPDRELDAQYLKTKIDNGGDF
VITQLFFDNKDYFEYVTRLRNIGVTARIIPGILPITNYQNLKKFCGLCGAGIPDKVKKIF
EPIENDLDATAHAGIQFAIQQCRELLEGGAPGLHFYCLNKLSPTDEILSTIRNT
>V6S5P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium cauense R2A-7|TrEMBL
MKVTQHIENANGKSLFSFEILPPLKGQNIKCIFDNIEPLMEFKPPFIDVTYHREEYEFKE
LPNGLLEKKIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDMDFLGIDN
VVALRGDAVKSEIYFKPEKEGNHFASELVTQISNLNNGIYLDADLQNTNKTNFCIGVAGY
PEKHMEAPSLDSDIHFLKHKIKNGADYIITQMFFDNKKFFDFVEKCRAAGITVPIIPGLK
PISTKKQLNLIPHRFKVDLPDDLIMEVVKAKDNEMVAQIGIEWCVAQSKELKEAGIPVLH
YYSMGKSDNIRQIATAVF
>A0A1W9KS49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax ferrireducens|TrEMBL
MTAVSPIPVSIEFFPPKTPEGVDKLRAVRQQLYALQPEFCSVTFGAGGSTQEGTFNTVRD
ILAEGVPAASHLSCIGATREGVRGQLATLKAMGVQRLVALRGDLPSGYGAGGEFQYASDL
VAFIRAETGDDFHIEVAAYPEIHPQAKSPESDLKAFAAKVRAGANSAITQYFYNSDAYFR
FVEDCDALGVQIPVVPGIMPITSSTQLMRFSDACGAELPRWIRLRLQGFGDDTASIKAFG
LDVVTDLCEQLRAGGAPSLHFYTMNQSAAVLEICDRLGL
>A0A0W8D9M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora nicotianae|TrEMBL
MKVIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEILMHMTCTNMAEADIKKALDEAKDAGIQNILALRGDPFDECDR
GFSHAVDLVRYIREKYGNHFCIGVAGYPEGHVEIKDKKADIQYLKEKVDAGADFVITQLF
YDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTSFCNTFVPDEVRKALEPIKDN
DEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPRRELPWQ
TSTLSKRASESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESHFAPSNT
STPRERRAMWGEAPAAKEDVRRTFVQYVRGEISSLPWCDAALHAETSTVQQELAAANSAG
FLTINSQPRVNGALSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKKPSIQYH
AVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKLWASLYE
PGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSLPPRRKDERRR
>J3BE85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. CF122|TrEMBL
MALNSAARRKIGISFEFFPPKSEEMEGQLWNTVSELQDWDPDFVSVTYGAGGTTKAPTLA
TVSRFLAETPLATASHLTCVGATKDETHSVIETFRKVGVKHFVALRGDAPGGVGAPYQPH
PGGYANAAALVAGLREIGDFEISVSAYPEKHPESRDTAADIDMLKQKADNGATRALTQFF
FDNDNFERYLEQVRAAGINIPVVPGIMPIQNLTQLKRFAGACGTLIPAFLDERFAGFDDK
PEERAKVAAEVAAEQIEDLARRGLTDFHLYTMNRAPLVSAVLTNLGFTRDGAKKAGAAA
>K6YLD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraglaciecola mesophila KMM 241|TrEMBL
MVSYAQGIDALNQSLSEVKGINVSFEFFPPKTETMEKTLWKSVERLAPLKPKYMSVTYGA
NSGERDRTHEIVKRIQSETGIAAAPHLTCVDASRDELKQIAKDYWASGIRKIVALRGDLP
EGYTEHVSYASDLVALLRDVADFDIAVAAYPEKHPEAPNSQFDLLNLKRKAEAGANQAIS
QFFFDAEVFLRFRDRAAAAGIDMDIVPGILPVTNYQTLQRFAGFTNVHVPNWLHKMYDGL
DKDDQTTRNLMGASIAMDMVKVLAKEGIRDFHFYTLNRCELSYAICHMLGVRAD
>A0A1M7IEH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus solventivorans|TrEMBL
MTLTAPRISFEFFPPKNLDQSFKLWETANALAPLGPDFVSVTYGAGGTTRQLTHEAVTAL
ASNYGLNVAAHLTCVEATRAETMQIVDDYAAAGVTEIVALRGDPPQGADRFRPHPEGFAD
SVELIGAIAARGGFTIRCGAYPEPHPESPDTAADVSWLKRKIDAGASSAITQFFFDADVY
FRFRDACDAAEIAAPIIPGILPVQSWAGAKRFAARCGASVPQWADEAFAAAGPEGERALA
IDMAAGLCRRLIEGGVERLHFYTVNRPDMTLAVCKALGIEARQAQVA
>A0A7K6QLF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Climacteris rufus|TrEMBL
MVNETQQSCSGSSSSRSDGSSSGSESSKDNSRCSTPVLDAERHERLREKMRRRQDAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRSYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A3Q4GHG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neolamprologus brichardi|TrEMBL
MVNQVQRGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQSKEKITGYLAKAKHLGLKNIMALRGDPVGEDWEEEEDGFNYAID
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNY
GIQQAVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELQNEGSVFEVFTCYITAQPNRCGHKVKCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVNGRNLTNAPEMQPNAVTWGIFAGREIVQPTVVDPVSFMYWKDEAFALWIEQWGK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPELHSEETV
>A0A7U4AS09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus M013|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPKKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A075JZ83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyella japonica A8|TrEMBL
MSSISFEFFPPKTDEQRAQLDQTATLLKPHAPEYVSVTFGAGGSTLSYTGETVHRLHTRH
GLPVAPHLSCVGGTRAELAALLDDYRAAGYRRIVALRGDLPSGMASPGDFRYASELVRFI
REHTGDHFHIEVAAYPETHPQADDALADLRHFKAKVDAGANGAITQYFFNADAYFRFVDD
ARRLGVNVPIVPGIMPIANFSQLKRFSDMCGAEIPRWIVKRMQAHGDDAASIRELGADVV
AQLCRRLLDGGAPGLHFYTLNRARPTRAILDRLHG
>A0A8J5BBW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradysia odoriphaga|TrEMBL
MNAVTNKDYLVADMALAGWGRRELTIAETEMPGLMAIREEFAASQPLKGARIAGSLHMTI
QTGVLIETLVALGAEVRWASCNIFSTQDHAAAAIAATGTPVFAVKGETLEEYWQYTHQIF
EWPNGQNANMILDDGGDATLMLHLGTKAEKDIAVLANPGSDEERILFAAIKQTLARDPKC
KRLSLFEAASCCLFGDHDGIDTSLDIECRSPAGGCLSAAGYYRGQFWFGADSGAGAGFNE
YAGQAGSGVADLAYHHRDDGSLSFRAQCSVVLVRRLRAARIPGQGVLVGFGGRLVVQPSR
RFAFRVDTLMTEMISPALSLEFFPPRDVAAQERLVRAAKQLLVIQPKYVSVTFGAGGSTR
EGTADTVRMMSNMGCDAAPHLSCIGATRDDLRHMLAAYREAGVRRLVALRGDLPSGMGGD
AGELRYARDLVAFIRQETGDLFHIEVAAYPEMHPQAASPSADLRHFVEKVQAGANAAITQ
YFFNADAYFDFVDRAQAQGVTIPVVPGIMPITNYSQLLRFSEMCGTEVPRWIRLRLAEFG
DDKASIRAFGTDVVTELCQTLLDNGVPGLHFYTLNQSEATLSIWKNLAL
>A0A0D6TAF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. 228|TrEMBL
MTDLPPVDFDRWQPSYDPPPPGHVSGSRLERVLRQGQFAVTAELNPPDSADPADVFAAAR
PLARVADAINATDASGANCHMSSIGISALLTRAGIGTVYQISCRDRNRIAIQGDVLGAAA
MGVRNVLCLTGDGVGVGDQPGARPVFDLDSISLLRTIRTMRDDGMFLSGRRITSPPRMFL
GAAENPCIAPLDWRPDRLAKKVEAGADFIQTNYIFDVPTFARFMARVRDLGLDRRVFILA
GVGPLASARAARWMRSNVPGVHIPDAVIARMERAADPGEEGKRLCIELIQQIRAIAGVSG
VHVMAYRREHLVSEIIAQSGVREGRPAD
>I3BGP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum 44B|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A1Z5SLA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii EXF-2000|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMSYDAEIFIEWAKKVRAAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAQLFVKYMSGKVETLPWSEQPISPESNVL
TNDLVNLNSRGLLTINSQPAVDGMKSSHPVYGWGPNNGYVYQKAYLEVLIPPSLIAELIR
RMDANPDITYYAVNNSGELKTNAPQDGGPNAVTWGVFPGKEIVQPTIVETISFLAWRDEF
YHLGSEWAKCYDEGSQSKNLIKEITESWYLVNIVDNDFRNMRGIFPLFDGLKVDGVEPTA
AAVNGAAVNGEANGGDVEKKEGARKPEVNGVPDGNNAVNHADGPAVNGQVKN
>A0A2G2AES4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pelagibacter sp|TrEMBL
MENQSLLQQKLLDKVFVYTAETTPPDASDKETLLKNVMPLKGIADAVNVTDSPGAKAHMS
SLTAAIILAQNGIDPILQLTVRDRNRLALQGDLIGASALSVNNILCLGGDNPKSGDQPEA
KIVNDIDSLTLVSTANMMRKEKKFPSGRVIDPPPKLXIGXAEVPTMGKPDPKKILEKINN
GVDFFQTQYVFDAKLLNEYMKVLGDEGILEKTNFIIGLGPFASAKSARWMNENLFGVDVP
DQIIKRLEGSEDQKEESKKICIELIEAFRNIQGVKGIHLMGHRKEEIISEIIKKSKK
>A0A8I0IAI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris|TrEMBL
MMSPDPPSRAATITDAYSLEVGAHDMPALTAAAPQIMRGSSMFIPYLPSQNDDARLAAAQ
RVRALGFAPMPHLSARRIASRYALQAFVRRAVDEAGVERCLVIAGDAPSAVGPFSDSVSL
IETGVFERSGIKAIGVAGHPEGHPSMPASAQWDVLERKCRSIAERGMAPLIVTQFAFDAD
TVLTWLEALRARGIAHPVHVGVPGPAGVAVLARYAARCGVGACASMLSKYGISLGKLFGT
AGPDRFVDRLTAGLSEAHGDVSLHFYPFGGIAQSVAWVEQYRSRHARPLAD
>A0A7R6VY71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Carsonella ruddii|TrEMBL
MKKISFEIFPEKDIKKSIEFINFLKKKNPDFISITCSKEDNYSFIEIIKKNTDIKIIPHI
ICNTLFSVIIKILKFIKIKIFSFIIISGDDCKNNSYNYIVKIRQLFGHIIKIYSGIYLEE
HKITKNFNKEVLFVYKKKKIGINLFLTQFFYNFSIIKYYLNILKKSGVSKILIPGIFPKK
KIQDVLNFTNKCKIEIPNWIVKNYNFINFKNYYLSNLKNFNHFHFYTFNKTKNILYYLK
>A0A6N3WX68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAAKLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAIDADSDLKYFKAKVDAGADAAITQYFYNADAYFHFRDA
AQRLGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQAYGDDADAVRAFGAEVV
AALCERLIAGGVPALHFYTLNLAKPTTQVLQLLGR
>A0A1J5I8P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacteraceae bacterium CG2_30_61_12|TrEMBL
MKAGSNLEKVLTSGHFAITGELGPPRGANADVVRKKAEFLRDKVDSINITDNQTSVVRMS
SIAVSRIVIEMGLEPNAQMTCRDRNRIAIQSDLLGASALGIKNVLCLSGDHNKFGDHPQC
KNVFDLDSMQLIMTLKHMRDEGKVLGGQELDGVPKFFIGAAANPFGDPFDFRVTRLAKKV
EAGVDFVQTQCIYNMDKFRTFMKQAVDQGLTEKFHMLAGITPLKSLGMARYMAKFVPGLE
VPDYYLKRLQGVEKKKQADEGIKIAVEQIQEMKETPGVAGVHLMAIEWEHRSPEIIEAAG
LLPRPKLD
>A0A511AXU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter wancherniae NBRC 103581|TrEMBL
MTDILSNWLSETRIDGLLSRNSAVPILSFEFIPLRTDAMELRLWHYIRHLAPLAPRFVSV
TYGAGGTTQAGTLSTVLRLKRDTDLIPAAHLTCVGVTRADVNDLARCYRDAGVNYIVALR
GDLPAGVADYSPRPGWHMPMPVILLPVCVVSSLVWWRWNRFVPCRPMDLTSFMSPR
>A0A2E0FKX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MKVIDHINGSKKTRFSMEILPPLKGRSIQSIYDGIDPLMEFKPPFVNVTYHREEHVYKER
HDGLLQKISVRKRPGTVGICAAIMNKYQVDAVPHIICGGFTKEETENALIDLQFLGIENI
LALRGDPIKNETHFIPNKAGHKYAVNLIEQVVQMNEGNFLHEETGNSTATNFCIGAAGYP
EKHFESMNLKTDLKYLKDKVDAGAEFIVTQMFFDNQKYFDFVSACREKGIDVPIIPGLKP
ITTMKHITFLPKFFHIDFPEELSSELEKCKTNDDVRQVGIEWGIQQSKELVDYGVPLLHY
YTMGKSQTVKAIASEIF
>A0A1M6NGU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reichenbachiella agariperforans|TrEMBL
MIDCMLKDKLLQNKGQYLFYGLTPPKYTTDKEKIQAIADKQIARLRDIKLDALVLYDIQD
ESSRTDVPRPFPYMQTLDPGVYSAQYLTALDIPKIVYKSVGKFTPDSFQDWLKENPNKIE
YSVFVGSPSAQENGLTLQEAYAARLASASEVLIGGVTIPERHFKKEDEHLRVTRKIENGC
SFFISQCVYSIDNAKDFLSDYYYHCLETKTPLAPIIFTLTPCGSLKTLQFMEWLGIYIPK
WLRNDLKHSENILFRSVDICKTVAKELLEYSRVKGIPIGFNIESVAIRKAEIDASIELLR
EIEMMQRASALKNELLAGNS
>A0A077P922|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus bovienii str. oregonense|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPSTTTMEQTLWKSIERLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKDKTGLDAAPHLTCIDANREELRNIAHDYWESGIRHIVALRGD
LPDSSGKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>A0A2D8CSJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MXVTEYIANRKKTIFSFEIIPPLKGKGIEDLXSGIDPLMXFNPPFINVTYHREEYDYXKM
GNGLLKKVSIRKRPGTVGICAALMNRYKVDAIPHIICGGFTKEETESALIDLKFLGVDNI
LALRGDPMKNESAFVPTEGGNAYALNLIEQINEMNNGQYLYEETKNSPSNFCIGTAGYPE
KHFEAMNLSTDMKHLKKKVDAGAEFIVTQLFYDNEKFFDFVKKCREIGIKVPIIPGIKPI
TNLRHLSFIPKFFHVNFPESFSNELEKCKTDEEIKRVGIEWTTAQCKELVKADIPVIHFY
TMGRGTAVKNIAKEIF
>R5KZV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:161|TrEMBL
MNIADLFKKKTVFSFEVFPPKKESGVETIYKTLEELKQLNPDFISVTYGAGGVGVANATT
VDLCSKIKNEYGIETIAHLTCLYNTKEDIDRILEELKEKGIDNILALRGDVNHNFELKHD
FRYASELTEYIMSKNMGFNVSGGCYPEVHQEAESMIADIKNLKKKIDAGADHLISQLFFD
NNAFYDFIEKVRIAGIDVPIEAGIMPVTNKKQIERMVSMCGASIPAKLSKVLQRFGDNPE
AMRDAGISYAIDQIIDLVANGVEGIHIYTMNDPYIAGKITKSVESIIKN
>A0A6J0P231|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raphanus sativus|TrEMBL
MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSHGPSFCDITWGAGGSTA
DLTLEIASRMQNAICVETMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEADGLATPESYQSDLAYLK
KKVDAGADLIVTQLFYDTDIFFKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK
IPAELTAALEPIKDNEEAVKAFGIHFATEMCKKILAHGITTLHLYTLNMDKSAIGILMNL
GLIDESKITRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPQGRWGDSRSA
SYGTLSDYQFMRPRARDKKLQQEWVVPLKGIEDVQEKFKELCLGSLKSSPWSELDGLQPE
TKIINEKLGKINSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSEDKLD
TLVEKSKAFPSITYMAVNKAGNWVSNVGEADVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFEIWSRSWANLYPEDDPSRKLLEEVKKSYFLVSLVDNDYINGDIFSVFA
>A0A848RQL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomonas sp. JC2975|TrEMBL
MSAHGTADGVAPCPAGTPFSFELYPPRTEAASRALPDTISQLASAGPDFMAVTYGAGGSS
HDSSLDVVRRIVRDTSVPVMAHLTCIGSSHEQAARMIREFLDAGVTRFLAVRGDPPVDAP
ADAPLGDLKSAAELVQLIHRIQAERAPYREIPLLGLPHASVVGKAEKVTIAVGAFPNGHP
RSRSRSQDIDTLLAKQAAGANLAITQMFFHAEDYFAFVDRARVAGVTFPILPGLMPATTP
TVLRRMLDLSGEDLPSELGIRLEVEPTDEGRREIGIDYAARLAERLVAGGAPGIHLYTFG
RPRTALSVLERCGLVDTAAVGS
>A0A1H4EMY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter hartonius|TrEMBL
MKITEHINAAGGKTLFSFELLPPVKGKSISDIYNAIDPLMEFNPPFIDVTYHREDYIYKQ
HDNGLLEKVSYRKRPGTVAICAAIMNRYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARHADSGFIPTPGGHAYATDLLEQVANMNKGKYLFEDHDAFQTDFCIGVAGYP
EKHFEAPNLKTDFKYLKQKVDMGAEFIVTQMFFDNSKYSEFVAQCRLNGINVPIIPGLKP
ITSSKQLISLPKIFHLDLPDDLSEAIQACKNETEVKEVGIEWMIQQCKELIQIGAPVLHF
YTMSNPEPTKRIAQAVF
>A0A423H3X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas brassicacearum|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWSNLKLPR
>A0A2D6WN37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puniceicoccaceae bacterium|TrEMBL
MSRISQTIASGKHSLSLEFYPPKSEKAIAQLEAASRALRQLCPDFVSITYGAGGSTRNST
LNYAGTLKDVHQYTVMPHLTCVGHSKEELHKIIEKYQSHGFQTLMALRGDPPNGAPQFSA
HPEGFTYASQLVAYIKDQFPKFEIGVGGYPEKHPEASTQSEDIQNLKKKIDAGADFITTQ
LFYRNEHYFRYVDACRKVGIDCPIVPGLMIPTALEKVERFCKFCRAELPETLRKALSLAL
GNAEATRAVALDWTFEQIQSLIENGAPGVHLYIMNQSEYALALHQRLASAGILKR
>A0A1M4ZTK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kaistia soli DSM 19436|TrEMBL
MMTDATARASRSSRSPSDLSVSFEFFPPKTEAMEETLWRSIERLAPLAPDFVSVTYGAGG
STRERTHATVARILSETGLKPAAHLTCVGATKGEVDAVVDSYAEAGVRHIVALRGDPVEG
IGTAYRAHPGGYDRAADLVEAIRSHHPEIEVSVSAYAERHPESPDWSTEIDNLKRKVDAG
ATRAITQFFFDNDLYSAFLDRVAAAGISIPIVPGIVPVLNFSQTAKFAQKAGASVPDWFA
ARFEGLEEDQATRQLVAAAVCAEQVLDLVDRGVSDFHFYTMNRADLVYAICHLLGMRPVK
PAAPDAAAA
>A0A0K8N4P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter frateurii NBRC 101659|TrEMBL
MAAQTGPLPAISFEFFPAKSEKAAATLLENAKTLAAFGPQFMSVTYGAGGSTRDRTLATL
KDMVRETGAPMAGHLTCVGASREEVDAVARAYWDAGVKHIVALRGDPPPSAGGVYEPHPE
GYAGAVDLVRGLKEVAPFEISVAAYPETHPAALSPQSDLEHLRAKIDAGADRALTQFFFE
ADTFLRFRDRAAAVGIEQPIVPGILPVGSAAQAWKFAEMCGANVPRWMRDLFDGLDETPQ
TRTLVAATIADRLCQTLRTEGVEQFHFYTLNHADTASALCRLLKHRPL
>A0A448Y3M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. 76-1|TrEMBL
MVSYAQGVDALNQSLSELRDIDVSFEFFPPKSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAQDYWDSGIRRIVALRGDLP
PGVKDTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIS
QFFFDTSVFLRFRDRAAAAGIDLDLVPGILPVTNYQTLVKFAGFTNVHVPGFLHKMFDGL
DDDDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRAG
>A0A0L6ZEX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium homopropionicum DSM 5847|TrEMBL
MFIKDLFSQKKTVISFEIFPPKKDTSIDSIYKTIDALAPLNPDYISVTYGAGGSTSKNST
VEIASIIKNKYNIEALAHLTCIASTKEDINIILQQLKENNIQNILALRGDFPQDPDFKFP
NPLHFTHAIDLVQHIKKDNYFSVAGTCYPEGHIEAKSMKDDIVYLKRKVDAGTDFLITQL
FFDNNLFYSFKEKTDIIGIDVPIEVGVMPVINSNQIRRIASLCGAHIPEKFVKILDRYID
NKEALKDAGIAYATEQIIDLISSGVSGIHIYTMNNPEVAEKIVHNISSIVTALNNSNGEK
>M3D6H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerulina musiva (strain SO2202)|TrEMBL
MHITEKLRQAHSKGQATCSFEYFPPKTAQGVQNLYDRMDMMHGLGPAFIDVTWGAGGRHS
SLTCEMVKVAQTAYGLETCMHLTCTDMERSKIDDALKEAYKAGCTNILALRGDPPREQEK
WEATEGGFRYAKDLIVHIKKTYGDHFDIGIAGYPEGLDETCGADEHIIYLKEKVEAGGTF
IVAQMCYDADIFIDWVKKCRAAGIPETVPIIPGIMPISTYAAFLRRANWTKAHVPPHWME
ALEPIKNDDAAVREVGRDLIVEFCQKLLDFGLMHLHFYTMNLAQAVTMVLEKLDLLPPAE
SPHPDLKPLPWRQSLGLNRREENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
GLDEYGIGLKGTNEQNRKIWGEPKSMQDIVNLFVGYMRGKVESLPWSEAKINDEANTLVD
DLVKLNSRGLLTINSQPAVDGVKSSHPTYGWGPRNGYVYQKQYLEVLISPTLIDTVISRM
DRDPDITYYAVNCTGELKTNAPTDGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYH
LGLEWSKCYDEGSESRKIIREITQNWYLVNIVHNDFRQQQGIFPIFDGLQAPGLQDIAEV
PGVNGHADTNGDLPETNGVPDGNNAVNGADKAASSNSAQNN
>A0A1I7F9U6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium KHP3R9|TrEMBL
MSDKLKISELIYQDPKPVFSFELLPPLKGNSIRQVFDTIDRLKEFGPKYINITTHHSENI
YKEDEKGIIRKMNVRRRPGSVAIAAAIQNKYGIRAVPHIISQGFSKEETEYALIDLSFLG
VTDLLLLRGDTKKLDADQRKLDCHQYATGLQEQVNNFNKGIALDGSSFPPPEVPFSYGMA
CYPEKHEESPNMESEIFYTKMKVQNGADYLVTQMFFDNRKYFEFVDRCRAEGIGVPIIPG
IKPIHLKNQLNVLPKIFRTEIPEELARELRQCNSDADAVEVGVEWCLLQCRELVRRGVPG
IHFYALGATESIYRVAREIY
>A0A7J2IE93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon|TrEMBL
MSKLSENLGRTFLVTAEIALPRGPGLKEFMHEIEEFRRLTSKLHGVNAVDNPGAMLRMSS
LAASIILKQNGLEPVYQLVGRDRNQLALQADLIGAAAFGIENVLALTGDPPNCDSSDHPK
AKAVFDLNSITLIKAIKLMNRGKNLAGGDLNKPTNFFIGAALAPNAVSVKGEIHKTKKKL
DAGVDFFQTQVVFESSVMGDFLNRCESLIEEDIRDRVLLGVLPPYSHNLIKFLRKIPGIV
IPDKIERRIKGASDPMEEGINIAAEVIDEAREMGMAGVHIMPLGRVEALVRLLEDL
>A0A431TZ15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter gummosus|TrEMBL
MKVTEHLTRAAGKTLFSFEVLPPKKGENIQSLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFTKEETENALIDLHFLGIDN
VLALRGDPIKSEGQFKPEPDGHAYACDLIGQVADLNKGAYLDEEQDDTWATNFCIGTAGY
PEKHFEAPSHAADLRYLKHKVDRGAEYIVTQMFFDNEQFFNFEKRCRAAGIHVPIIPGLK
PLTTKGQLTALPRAFYLNLPDELVDAVHLAPDNAAVREIGIEWCINQSRELMAHGVPVLH
YYSMGKAEAVRRVAAALF
>A0A6G9YCP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia arthritidis|TrEMBL
MPARRIRVPRGRLDGAPTCSHYTGLVTFDNVRGRATPGLPSTARPNVSHTPSVVQSLRTH
ASRSVPFSVEFNPPRDAAGEARLWRAVRQFERMHPAFVSMTYGAGGSTSDRTVRVTGELA
QETTLLPVAHLTAVGHSVAELRSLVGGYADCGIRNVLVLRGDPPGDPLGEWRKHPEGVAY
AEELVRIVRDLGDFHVGVASFPQGHHRSPDLDHDTRYLAAKLRAGAEYSITQMFFEVDHY
LRLRDRIAAFDPVEGAKPIIPELMPITSLRTVSRAEELCGRPLPAAVMERLHRAAGEDPE
ANQAAVREVGIEIATEMGQRLIAEGAPCLHFITLNFAKATSEVLTNLGYGVTAAPLSA
>A0A1F9GW45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_43_9|TrEMBL
MAKKLPLRELLKQNSPIVSDGGMTTSLYDKGFYINRSFEELSITDPHVVRDVTQEFKRAG
AKLLSTNTFNALLPKLTEYGLQEKLEEILIASVKITKDLSDNDSYVLGAIGPLGIVVEPL
GPTSMNEAKAYFAKNIEIMDREGVDAISFLGFHDLNELRAAIMAAKETTEKPIFAHISVQ
ENMKTFYGHTLNEFVRLVEEFDIDVLGCAGEVGPSGMLTSAEKLRPLTKRPISLLPNAGV
PKYVNDQYIYLCNPDYIGKYAKRFIQAGVNIVGGHCGVHEKHIRAISNALRMTSSSMKSE
SFYAENTKSSVTIDPPLPPTPKKNRSKLGYALETGKRVFSIEVVPPKGVDLKKFHEYCEK
LELGGVEFVNIPDGARAVARISSLQLASYVKQHLNLEPIPHFTARDRNLIGIQSDLLGAY
VNGIRNVLLITGDPPKLGNCPGATAVYDVDSIGLTRIVSRMNQGLDLGGSRFGDPAEFLI
GVALNPTTPNKKLEIDRLKYKVESGADFIMTQPIYDLSIYKSFIDESGSHNLPILMGIWP
LVSLRNAEFLKNEVPGVSVPDWVLREMEKAGDSKEEAIKRGVEIAIKTMEEAKNFVAGFQ
VSAPFNRIDIALEVIHAIRN
>A0A7C7ZP79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thioglobus sp|TrEMBL
MKISFEFFPPRTEQGKQALTQVRKELSTISPEYFSVTFGAGGSTQDATLETVLDIQQNDG
VPAAPHLSCIGSEKNKIIELLDQYKVAGINRIVTLRGDIPSGVRDIGDFHYANELVEFIK
TQYNDYFHIEVAAYPEMHPQAKNIDTDLKHFIAKVKAGANGAITQYFYNADAYFRFKDEV
EKAGVDVPITPGIMPITNYTQLLRFSTMCGAEIPKWILERLKLYENDLDSLAEFGTEVVS
ALCQTLKNQGVDSFHFYSMNRAQPSLNIAKNLK
>A0A7R9BFB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Notodromas monacha|TrEMBL
MPESAVGDIGNEDSPSSVVLMSSVVGQGQGQVLHQQQQQQHALRPSSSFCSSLASDSESG
MDSEVEWDEEPPEGGYNDGDEAAVSVPGAYMTLRDKIHERIKAGDKFFSLEFFPPRTKAG
AVNLLSMFERMGSAGALFIDVTWHPAGNPAGETETSSMGIANAALNYCGLETMLHMTCLG
KTPQVIGEYLEKAKRLGVRNVLALRGDPIPGGEPDQPDALHHAVDLVKLIRQTTGRHFVI
GVAGYPCGHPEAESYEKDLEYLKEKVDAGADLVITQLFFKAEHFVQFEADCRRVGITVPI
IPGVMPIQSYDSLRHIVKLSKLQVPDEIKGILEPLKWNHEAIRNFGIRHAVDMIRTLFRA
GVAPGVHLYTLNREVASERILKEVGLWDSGPQRCLPWKTAANVKRCKEDVRPIFWARRPK
SYVYRTQKWDEFPNGRWGNSQSPAFGELKDYYLFYLKNSTPKEELLSMWGERLTCEKDVW
GVFERFISGEINEHGVKVTTMPWSDAELEPETFLLKDKLAELNRKGILTINSQPSVNGMS
SEDPTHGWGPKGGYVYQKAYLEFFTAPDVVDHLLALLPAFPTVNFHVIDKRGRVNLTNIN
KHRCIAVTWGVFPGMEIVQPTVVDPRSFKVWKDEAFELWTEQWGKLYPGDSESSRLIESI
ANSYLLVNLVDNEYIQPTRLWELLDAVLKRKAATSTADR
>M8DS52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacter thermohydrosulfuricus WC1|TrEMBL
MLKNENLCTKLKKRKFVVTAEISTPKGVDITKTIEEARKLKGIVDALNITDCPMANMRMS
PIAVAHLLQDHLNIEAIFHLTCRDRNLIGLQSELLGAYALGVRNILALTGDEPSRGDTPQ
AKGVYDVDSVGLLKIISAFNRGYDYNGNKLDSPTEFCAGTTANPNDLRDEALEKLKVKIE
AGAEFIQTQPVYDEEILFKFIEKIKNFNVPLLIGILPLKSYKMAVNLNEKVPGIDIPEKV
LERLKDGGREEGINIAVEFIKRIRSEVAGIHIMPLGSTNVVLEIISRVDDLVCDFAENNV
QMN
>A0A658IQD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Newport str. CFSAN000835|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>I2DIU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. KJ006|TrEMBL
MRIMKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLD
MQKDGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASEL
VSFIRAEHGDWFHIEVAGYPEYHPQSRSPAADLQNFARKVKAGANSAITQYFFNADAYFR
FVDDARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFG
ADVVTGLCQRLIDAGVPGLHFYTLNAAAATRTICERLTM
>A0A1N6D3K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasphingorhabdus marina DSM 22363|TrEMBL
MGSPVASEAVRDLLEGYSAEVTTPDRRSLDTAAKMMPANAPVYVASLPRDTPESQLDVAR
MLKELGLQPVPHIVARNIPDRRSFEKIIYDLSRYAGVDRALILGGDRDRPVGDYHSSLQL
LKSGILEDHGIKRVAVGCYPEGHPAIADDILETALFEKIDTASRGGIDLRLITQLCFDAD
AICGYLAALRSKGVTSKIRVGIAGPAKTPTLLKYAAICGVGPSLKALKKQRKITRGLLKT
QTPATLLRNIAEQNRRNALLDITGVHFFTFASLSGTIDWAEKQLGRGS
>A0A373ZAA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF15-6B|TrEMBL
MIQEKEHKGVVFSCEVFPPKRDDDIYQIYKTLDEIKTLKPDFISVTYGAGGSNSKKTATI
AAYIQNICEVEALAHMTAVGMDEASLRALLFELKKKGVENILALRGDKPRTMSQEEFDRR
YFKYATDLIPEIKKNGDFFIAGACYPEVHPESKNQEEDIQHLKQKVDLGLNCLITQMFFD
NNAFYSFMDKLEKAGIDIPVHAGIMPVTAAKQLGTSVTLSGSSVPVEMSNMIAKYGENPE
DMKKAGIEYAVNQILDLKKHGVAGVHIYSMNKADVTKQIYEASF
>A0A4Q5N1D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. HLT2-17|TrEMBL
MPFDRPGDRPSPPARAAIDRPTVSFELFPPRTPKSFDALTVTIQALAAVRPDFISVTYGA
SGSTRQTTRELVRHLLAHTPVLPIAHLTCVGVSREDVVAVIEEFLDEGVRNFLALRGDPP
KDQPNWRPRTGELVQASELVELLREVEAARCVTSASQALRGAARKLSVAVAAFPAGNPSA
GSTREQDLRALLAKQEAGADFAITQVFFEAKSYLGLVRDARDLGITIPIVAGVIPTTDPA
RLVRLEELTGVQVPTDLLARLAAADDPAERHRVGIRASVDLADEVLDGGAPGLHIYTFNQ
HEAALDLLEGVHLGGGAPMAPEPASEPRVTASHPNYLTI
>A0A2R7QSV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. HMWF013|TrEMBL
MSPPSLIETHPNLSESSAPVALSYELFPPRSPAAAESLWNTIRELETTDPDYVSVTYGAS
GSNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAEIIGDLLDTGVRGILALRGDRPQ
DGTPPVPGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEEHDVEVL
LAKQRSGADFAITQVFFHTDQYADLLSRARRAGVTIPIIPGIMPFTSPRRVKRLGELSGV
EPDPQLLARLAAADTDAERHRIGVRATVDLAKAALDAGAQGIHLYTFNEHQSALEVLDKL
ALPRHSRSAGRRTAILQRQLAS
>A0A1C4VL62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora haikouensis|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTAQGERLLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVR
GDPPGDPGGEWVRHPEGVLYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCATPILAGVMPVTQLSTIERSVQLSGAPF
PPALAARFAEVADDPEAVRRLGIEQAAEMCRRLLDEGVPGIHFITLNRSTATREVWQQLQ
VGARV
>A0A1H6M9H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus alkenifer|TrEMBL
MTFTAPRISFEFFPPKNLDQSFKLWETANALAPLGPDFVSVTYGAGGTTRQLTHEAVTAL
ASNYGLNVAAHLTCVEATRAETMQIVDDYAAAGVTEIVALRGDPPQGTDRFRPHPDGFAD
SAELIAAISARGGFKIRCGAYPEPHPESPDSAADVAWLKRKIDAGASSAITQFFFDADVY
FRFRDACDAAGIAAPIIPGILPVQSWAGTKRFAARCGASVPQWADDAFAAAGPEGERALA
IDMAAGLCRRLIEGGVDRLHFYTVNRPEMTLAVCNALGIEAPKAQVA
>A0A3B0BSF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces klenkii|TrEMBL
MALGTASTRTDHARTVRELLASGERSYSFEFAAPRSEKGERALWDAIRRIEAVGPTFVSV
TYGAGGSSREGTVRVTERMATDTTLTPVAHLTAVNHSKAELRNIIGQYADVGIRNMLALR
GDPPGDPMGEWVRHPEGLHYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADFAITQMFFYPDDYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFAQLSNAAF
PPALAERILAVKDDRAAVRSIGIEYATELCARLMAEEIPGLHFITLNHSTATLEIYENLG
LHQRS
>R9J4Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 3-1|TrEMBL
MKISELLKTKEVTISCELFPPKKGSELKKAHEIVKEMAKVKPSFMSVTYGASGGISEHTV
DLANEVQNINGVLALAHLTCASSDRNKIQEVLKELQEHEIENILALRGDIPENLDFPLPD
QYHHASELIEEIKSFGDFCIGGACYPEGHPEAESIEADIEHLKRKVDAGCEFLTTQMFFD
NNIMYNFLYRTLKKGIEVPMIAGIMPVTNVNQIKRITSLSGTILPQRFRAIVERFADDPA
ALKQAGIAYATEQIIDLIANGVGHVHIYTMNKPDVAGAIFKNLSEIYHAE
>A0A672HC03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salarias fasciatus|TrEMBL
MCGGSSGWTVGGGESSKESSRCSTPVLDADRSDRLRDKMRRRIESGDCWFSLEFFPPRTA
SGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLTC
CNQTREVITGHLAKAKHLGLKNIMALRGDPMGTDWEEEEEGFNYAVDLVKHIRAEFDSYF
DICVAGYPTGHPEAESYEEDLLHLKEKVEAGADFVISQLFFRADTFLKFLDDCRRIGISC
PILPGIFPIQGYQSLRQLVKLSKLEIPEEITEVIEPIKDNDAAIRNYGIHQAVEMCRVLL
DSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASR
PKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLQMWGEELMNEES
VFEVFTSYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELDKVNRRGVLTINSQPNING
KPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVSALLKVLKKYEPRVNYHIVNVHGLNLTN
APELQPNAVTWGIFPGREIVQPTVVDPVSFVSWKDEAFALWIEQWAKLYEDESPSRMIIK
YIHDNYFLVNLVDNDFPLENCLWQVIDDMFELINESLEQLRDSGDRLRAPGEQLGASGDQ
LGASGDGIGASGDGIGASGDGLGASGDGLGASGDGLGASGDGLGASGDGLGASGDGPSGD
QPHRDK
>A0A848E9B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas sp. JC162|TrEMBL
MNHPMSGTLARWLTGPRVAGLPAPSDLPAPGLSFEFFPPRTEKLEDQLWTCIRRLEPLGP
RFVSVTYGAGGSTQERTHQTVARLVADTSLTPAAHLTCVGATQEEVDAVARRYWDAGVRH
IVALRGDPPAGATTYTPHPGGYAQAEDLVRGLKRIADFEISVGAYPEVHPAAISADADLD
FLKRKIDAGATRAITQYFFDSEVYLRFIDRCLAKGITVPIVPGILPVSNFQQVVKFSAMC
GASVPAWMGHLFEGLEEDAETRRMVAAVVAAEQVRLLQANGVDEFHFYTLNRPDLTYAIA
HILGARPKKG
>F3KDB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium IMCC2047|TrEMBL
MSDFITDLLSNPLLADGASGSFLFERSGRLSEVNHVYEALNADNPDAIRDIHLAYLQSGA
RCLTTNTFGANSAYLKIMGEAGRVAELNNAGVKRAQEAIARFKEHTHSEKNYYILGSIGP
SCDDELTAEEAAEIYLEQVEALIAAGVDALLLETFNSLAEVKTLLELINTLPNKPPVIVQ
MALQQNANNDWNVAPTSYVETAAELGVSVVGVNCCTPWDASAFIEQANSLDVVKEHKVLL
SAMPNAGGFQRIGHRFMTAVNPEFMGKQARTFAAQGVRLIGGCCEVHPEHILEMNNYLQG
SQVNQNSVQVRSQDAMEPNGPEAKADNGPFSRKLMNGEFVVSVELLPSRGTSAAVLKHKI
DFVKQLADSGLADALDITDGSRGIPLIPPGDFIGNIRQTLGWTAETGDKLELIPHFTTRD
LNIMGLQSRLMGYYSQRINNVVFITGDPPKMSPTYPRSTAVFDANSVDMLNYTQHCLNAG
VDFGGQRLGKQKDPRTHFTVGAGFEPEALDSKSEIAKLERKIDAGADYIMTQPAFRNDAL
SILEPYRQRVAVLIGVMVLTGLEHAKRVGQVPGVTIPGSILERLARFDNIEDQAKAGQEI
AMEQIRWVRDNNWPGLYLMSPASHDRVIDTLSALK
>A0A8J2V5H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquisalinus flavus|TrEMBL
MSDRLKISFEFFPPKTEKMSEQLWGAIEQLVPLGPDFVSVTYGAGGSTRDRTHQTVSRIV
EETKVPVAAHLTTVNATKDEINQVLDDYWNAGVRHIVALRGDPPGGVGETFEATQGGYFN
AADLAKAATDRHGFEVSVGCYPEKHPESPDFALDIELLKQKVDAGATRAITQFFFDNDCF
FRYVDMVRKAGITIPIVPGIMPVNNFGALTRMAGLCGATIPGRIGRMFENLDDDPETREL
VAATLAAEQCLDLAEQGIDHFHFYTLNRAKMAYALCHMLGVRANSDTSQD
>A0A369KUC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. DQ26W|TrEMBL
MSTQVHPLGISFEFFPPNTDLGREKLMGVRDALAERNPRFFSVTYGAGGSTQARTLSTVQ
TVRESGITTAPHLSCIGSEKAQLRDLLHRYREQGIDSLVALRGDLPSGMGGIGELRYANE
LVEFVREETGDHFEIAVAAYPESHPQAPSFEKDLENFVRKMKAGANFAVTQYFFTADAYF
HFVERARAMGVEAPIVPGIMPITNYTKLARFSGACGAEIPRWIRKQLEAYGDDSESITAF
GEEVVSRLCQRLLDGGAPGLHFYTLNQATPCLRILDNLS
>A0A374UQG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. OM08-24|TrEMBL
MNIREYLKKSKLVADGSFGTYYSTKYKTDDIPEYSNITNPQRIFDIHTEYINSGARLIRT
NTFASNTYSLDCSLEKVKENIRAAFEIAKKAVDKSGKEVFIAGNIGPVPAVFQPDFEAVE
EEYYQIAKTFVELGVEILCFETFTDNEHILPAIKRIKDECNPFIIVQFCVNQFGYSEAGE
SAERLVSNTAFSKCVDAVGLNCGVGPAHMQQILSRINLNNNCFITAMPNAGYPLLVRNRV
KYADNPLYFASKVSDMALIGADIVGGCCGTTPEYIKDLAETVDLTPAVKSSETAAKKECE
KPIIKKGFFRNTDGTIKDKKLIAVELAPPFGADDKKLLEAAHSLKGLGVDVLTFPDSPSG
RTRIDSVLMAQKVKNETGFDVMPHICCRDKNAIAMRSTFLGASINGINNFLIITGDPIPV
MARQVVKSVFNFDSVGLMRIADEMNSDSLKNQPITYGGAINQGRLRIEAEIKRVQKKMDA
GAEFFLTQPVFTAEDAERLRRVKEETGARILCGIMPLVSRKNALFMKNEISGVNVTDEVI
ERYPESTSREDGENIGVELAKEMIAITKDFADGYYFSFPFNRTYLLKRIITEI
>A0A510WUN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus casei|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>N1JE16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blumeria graminis f. sp. hordei (strain DH14)|TrEMBL
MEKISNKIKALPPGQNYFSLEFFPPKTSTGTANLRARLERMSRALCPLFVTVTWGAGGAT
ASKSLDLAAMCQRDLGLTTCLHLTCTNVTQEFVDGVLERAYNLGIRNILALRGDPPRQEF
IKNHSDTKDTVEFERAIDLVSYIKAKYGDYFCVGVAAYPEGHADRENPDEQNLMHDLPYL
VDKVNAGADFIMTQLFFDVKAYDHFEKVLREHDSGCFKDLPIIPGIMPIQSYQTIKRTIK
LAHARIPPEFMARLDSVRSDDALVKQRGVDIVSEIVTHIKHTPSSAPGTRGFHFYTLNLE
KAVALILQRTSLIPSSQAIDELESNRNANSNECEANTNGTCPQDTRQATNSVDPDLFNRV
VITESKPSDPQIEATIFEASALSKPDYSRAATLAIIEGEGSLGRDATRDDFVNGRWGDSQ
SPAYGMIDGSCVILHMSRKQAIELWGYPSSIEEVTSIFLRHIEGSISAIPWSEDDLCHES
EAIKVPLRALNRKGWWTVASQPPVNGISSQHPIFGWGPPRGFVFQKAFIEFFLPSAAWSA
LRAKLESSSIAPDVSWYACNAHNVFKSSNPTINTSSEMGRTSRCTNAVAWGVFPGREIIT
PTIIEEVSLRSWAEEAFSIWSEWARICAESGSKSGKMSREFLEGVYEDLWLVNIIHHDYF
KEDALWDILLE
>A0A4S0WCF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2E.F.Ca.ET.166.01.1.1|TrEMBL
MNVRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWQREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A1V8RWB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudaminobacter manganicus|TrEMBL
MSAARPPQQDENPSGIDLPLDPLPGHTSPGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAQIFDGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
AAAMGVANILCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQ
LFLGGAINPFAPPHDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQRVRDLGYTEKVF
IMCGVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQICIDIIKEVKEIPG
VSGIHVMAYRQEEYVAEIVDESGVLKGRRPWHREARADDKIVADRLDQILHDGITETQVD
MVKSAH
>A0A2N2JWN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-15|TrEMBL
MSLQDRIRAGKFVLLGEFEPPKGADFSGLLKNALLTKGRLDAVVVPEMANAVLKASSLGG
CAFFQKEGIETVFQVCCRDRNRLALQADILAASALGIKNIMAVPGDDIRFGDHPQARTVN
DLDLIGLLETIHRLHEGRDLSGIELRGAPSFCLGSTMDAGAPGGLLTIEMENLKRKVDLG
IEFAITNPIFDLRRFDQFIKRLEVKISVMPTVLLLKSAGMARYIDRNVKGISIPQETITR
IQKASDKVKECVLIAAETIARIKDMGMAGVLISTVGWEDKLPWVLDEAKV
>A0A2N0KIF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Casp-Chloro-G3|TrEMBL
MKIRDLLKEKRTISCEFFPPREADGIPNVLRVIDRVKAYQPDFASVTYGAGGSTRAFTEE
ITMYIKRETDLEVMAHLTCVAQTREEIQSVLERLDQNGIENIIALRGDPPQGQTDFVPVA
GGFEHATSLIKHIRQNFQFGVAGACYPEGHVESRDLIQDIEYAKRKVDQGVDFLVTQLFY
DNDHFYAFLDRAAKAGINVPVLPGVLPILSTAQIRRFTGLCGATIPPELDRQLDQYADDD
NAVRELGIEYATKQVRELWDSGVPGVHFYVLNRSYSVSKILDNLGIEGHTAGT
>A0A1Q6SDH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:65_45_313|TrEMBL
MKIRDILNKDTATISFEVFPPKKSTDFGNVEAAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGEIQKQYNVPTVAHLTCVCADRSSIGVALTEMQAAGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKENGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIVPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNLSEILKA
>A0A4U1AKQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila sp. IMCC35006|TrEMBL
MKTESKLEKILAAGHLAVTSECGPPRGAKFDEVVTKSKYLEGIVDAVNVTDNQTAMVRMS
SLAASVIIKQQGLNPLFQVTCRDRNRLAMQADIIGAYAFGIDTMLCLSGDHTKFGDHPMA
MNVHDIDSIQMIQMVKDMRDKGIFQGGAEIKGAPKMFIGAAANPFADPFELRVMRLAKKI
AAGADFIQTQCIFNVDKFEKWMEGVRAKGLHKKCYILAGVTPCKSLGAARYMANRVPGMD
VPKEIVDRMASVPKEKQAEEGVTICVETIERLKKIEGVAGFHIMAIEWEEKVEEICKRAG
LLPRPQV
>A0A0Q9T1Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycicoccus sp. Soil802|TrEMBL
MALVHTSRDGRPGREPQSIPGMLAADHPSISFEFFPPKDDAGESVLWDAIRRLESVRPDF
VSVTYGAGGSNQDRTVRVTERIARETTLTPLAHLTCVGASVAALRQVVGLYAASGVRNIL
ALRGDPPGDPGGEWTAHPEGLNHATDLVELVRTLGDFTIGVAAFPDVHPASPSFEHDVDV
MVRKADAGASFAITQMVFDADSYLRLRDAVAARRDLPITPGLMPVTNFKQVARMSELMGT
PLPEAVVQRLQAVSDDPAATREVGVQIATELADRMLSEGAPGLHFITMNRSTATLEVYRN
LDLGARTAASRA
>A0A239N761|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium subroseum|TrEMBL
MSDHRFELVCEIEPPTRPDLTRVRHQIGVLSAVADSFLIPDNHIGRATVSSVAVAHEVQA
MGARGIACLNSRDRNLLGLRRDLLTASAYGVERFLFVYGDKPTVGGRTSELTVRGMIEEA
RGTAEDPAFAGRRPFQVGVTSGLRPVPTWKSAADFVFVQVSYSVDALLRWRESVSLQVPV
YAGVMVLASAGMARNLAATIPDIDIPDRLIDDVERDRNAGVDAACEQILAIRDSGAFDGV
HLVPVSRYREVAARLEREL
>A0MPA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Homo sapiens|TrEMBL
YPKGHPEAGIFEADLKHLKEKVYAGVDFIITQLFFEADTFFRFVKACTDMGITCPIVPGI
FPIQ
>A0A6L5PJ73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. SPF441|TrEMBL
MASSASLNLADARALLLSPLGPVARAGSNRDAVRVSFEFFPPKTDEAEANLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIITETSLRPAAHLTCVEASRDEVDEVIEGYKAIG
VDHIVALRGDPPGGAGIGGVYQPRADGYANATELTAAINRIGGFDVTVGAYPERHPESPS
IGHDIEVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLQ
RMCGACGASIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETAAAQ
>A0A1I0D3H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Clostridium] polysaccharolyticum|TrEMBL
MKLQEYLKENRLITDGAMGTYYAALKGNDRLVSEFANINEPEFIEEIHMEYIKAGARLLR
TNTFAASRDVLQVGAEEQENIIRAACRIAKNAVEKVTKENKQIESQPVFIAGDIGPIPYN
PDRTKEDIIKEYKRICDIFIEEKLPVILFETFSDLIMIQEVIAYVKEKSDVFLITDFCVN
HNGYSSMGIKASRLLEMAGKMEQIDAAGFNCGVGSGHMCQILKKMVFPKNKYIIAMPNAG
YPEKFQNRMVFRDNADYFVENMLEAAELGLDIVGGCCGTTPAYIKKLAQSISQKTVLKAA
AIEVVQEEQKEQKKPAIANAFYEKLKQGKKVVAVELDPPYDAKYESVIQHAQYLKEHNVD
IITMADSPRGRSRVDSILMSVKLVHDVGVSVMPHVCCRDRNMIAMRSSLLGAYINDIRNL
LIVTGDPVPSVSRSSISSVFDYNSIQLMNFMKEMNQEHFSDEPIYYGGALNYAGRIDKVV
ERMKKKADAGAAYFLTQPIYAPEDIERIHQIKERIDTKILCGIMPFTSFRNATFVKNELA
GIHVPDEIVNRYHPDMSRKEAEIVGAEIASEIIEKLYAFADGYYFMLPFNRVSFMDKITI
Q
>A0A653AS00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium neonatale|TrEMBL
MIDEYLKNRVLVSDGAMGTYYSEISGNDISYCEFANLNDKNTIKKIHSKYIEAGAKLIRT
NTFSANIYDLSVTHKALKEIIHSGIDIAKEATYNKDIFIGGSIGPIRKENSLDEFDEEIL
DEYKFIVDCFLEKKIDIFIFETFSNYTYLDEISKYIKEKNNETFILTSFAFKPDGFTRDG
LSVSKVLSYLENINEIDGYGFNCGSGPSHLCEIVKKSAINNKIIAVLPNAGFPEIIHERT
VYPNNPVYFAKKVSELKNFGVSIFGGCCGTNPSYVKELSSYISASKLGDNIKTNVVITNE
HTIKLKKNKFKQKLDDGEFVIAIELSPPSDTEISKVIEGARLCKENNVDLVTVPDSPMSR
VRADSVIMASKIQREIGIDAMPHICCRDKNTNAIRSSLIGSHIENIRNVLAITGDPVSDA
SKVQTKSVFNLNSFKLIELINDMNTEVFKEDGMLIGGALNLNVFNKEVEFNRMMKKIEKG
ADFFLTQPIYDDEAIEFLKVIKQRVDVKILAGVLPIVSYRNAMFLHNELPGVTIPEKYIN
MFSEDMTKEEGQSVGTEIAVDIVKKLKEVSDGLYFIAPFHRVSMLIDIIKQIRD
>A0A1M7YFR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerocolumna xylanovorans DSM 12503|TrEMBL
MELREYLTEHKLITDGAMGTYYSRFLNNDSAVSEFGNLTEEDTIVNIHQAYIKAGAELIR
TNTFAANRQTLNQTKEEQKELIKKAYQLAKRAVKKAKEQVYIACDIGPIPENGTRTEEDI
LSEYQDICNAFLEEGGDIFLFETFSDFYYLKPLVKYIRDKKPAAFIITDFCLNKNGFTAK
GISARSILETIEETDEIEAGGFNCGIGSGHMYQILRKLTLPAGKFIFAMPNAGYPEQFRN
RLIFMDNEGYFRENIQRICELGIDAVGGCCGTTPDYIKNMAEKLSLEESYRGERKVLSVM
REAKVEVRPNEFYQVFKEKKKVVAVELDPPFDAKDEAVIACAHRLKETGTDIITLADSPM
GRSRVDSVLMALKLHNETGLPVMPHICCRDKNMIAMRSCILGAYTNGIRNILVVTGDPIP
SEHRQSTTGVFDYNSIQLMNYVKEMNREHFAQEPIYYGGALNYGRGPIEKVIERMEKKIE
AGASYFLTQPVFTEEDIRRLEEIKAKVNTKILCGIMPLVSYRNANFIKNEISGIHVPDWV
VEKYRPDMDKAEAEWVGADIASQIIKDLSPYADGYYFMLPFNRVSLMEKIIIK
>A0A7C9M3V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp. AETb1-6|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTTELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSFGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGV
GPMASAKTAKWIRSNVPGIHIPDSVIKRLEGAEDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRKPWKREPNPVDQLVAERIEMARDGHEQDQQKLAGQAA
QQPL
>A0A0C1UCF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine actinobacterium MedAcidi-G1|TrEMBL
MKSTQLKLLDGMTYELIPLKNVHEQGEYLPKSSTISITCSPAKDIEATLELCESFLSKGH
TTIPHFAARMVESEEHVAQIVKRIESLGIETVFIIGGDADQRGPFNDAPGLLRSFLDKNP
KIKTVGIGSYPDGHPSIPESALAESLIKKQEMIYESNLNGYMATQMCFEAKTISSWLKNC
REAGVTLPCHLGLPGVVDMKKLINISLRLGVGVSSRYLKKNRKSVFKLLSPRGYNPNKLI
VPVSDYAEELDIAGIHCFTFNAVESTEAWRTKTMERLT
>A0A3L9M862|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 2JN-4|TrEMBL
MTKRVPISFEFFPPKTDVGAEKLRTVHQELQRLNPEFFSITYGAGGSTRERTLAAIHDFN
GSGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREYSGDHFHIEVAAYPEMHPQAESFDVDIQRFVEKVHAGANAGITQFFFNPDAYFYFM
ERLDKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSKSIKAFGHE
VIVKLCERLIAGGAPSLHFYSMNQTEPTQQLVVDLGLN
>A0A0R2RAQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium BACL7 MAG-120910-bin2|TrEMBL
MKVIDHIHAAKGKTLFSFEILPPLKGTRIDDLFGTIERLVEFGPKFIDVTSHREEFVYKK
RENGLLEKVHTRKRPGTVGICAAIQNQFKVDTVPHVICGGFSREETEYALIDLHFLGIDN
VMVLRGDALRADGAFKPEPNGHAFAIDLLKQVVDLNHGRYLHDEVENNNPSNFCVGVAGY
PEKHFEAPSLRTDIKYLKAKVEAGAEYIVTQMFFDNAYYFAFVDKCRAAGIEVPIIPGLK
PIATGGQLATIPRNFHLNLPDDLVDAVEAAKTPAEVKQVGIEWCIEQSKELMQKGVPVLH
YYTMGKADATEQIASVLF
>A0A059MPL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus aetherivorans|TrEMBL
MDRFRAPRGARIPFSVEFSPPRDADAEARLWRAVREFERLGPAFVSMTYGAGGSTRDRTV
RVTGQLAQETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWTR
HPEGLEYAEELVRLVRDLGDFHVGVASFPEGHHRSPDLEHDTRYLVHKLRAGAEYSITQM
FFDVEDYLRLRDRVVAYDPEQGAKPIIPEIMPITSLRTARRSLELSGSRLPAALEERLVR
AAGNGPEEDRAAVREVGIDVATEMAERLIAEGAPCLHFITLNFARATREVLARLGIAVPT
AV
>K9DJC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia timonae CCUG 45783|TrEMBL
METPDFSIEFFPPKTPEGAEKLRIAREKLADLNPKYFSVTFGAGGSTQQGTLATVREIQA
AGHEAAPHLSCIGATRESIRDVLKQYQDSGIRRVVALRGDLPSGYGGAGELRYASELVEF
IRQETGDWFHIEVAAYPEMHPQARSPQDDLQAFARKVQAGANAAITQYFYNADAYFQFVD
NVRKLGVDVPVVAGIMPITNYMQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLAGGAPGLHFYSMNQAAPTTAIWQRLRA
>A0A1T4RF76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter spongiicola DSM 21749|TrEMBL
MIPISFEFYPPKTDDQRAQLDRTATRLRERAPEYVSVTFGAGGSTLSHTPQTIQRLRGTL
ELDAAPHITCMGGSREEIRGLLKLYRAIGARRLVTLRGDLPSGMVSPGDLRYASELVEFI
RAETGDHFHIEVAAYPETHPQARDARMDLEHFIRKVRAGADGAITQYFYNADAYFRFVDD
LRKAGIDIPVVPGVMPISNFSQIRRFSEMCGAEIPRWVAQRMLSYVDDAESVRAFGAEVV
AELCQRLVQGGAPGLHFYTLNLAKPTLNVLSRLE
>A0A2E4N001|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MIYEIEKWIKEKLFDCQSCGQCVLSHTAMVCPMNCPKGLRNGPCGGTLEGKCEVLPEKTC
VWTEIDQRKKPSFETLHLSPQKELYNTASYVNLVNGKDRKTRLPQDVVDLGDIPASSSLS
EKMYGEEFVVTLEIASPRTEDGLRRVERIMRRVADHVDAVNTTTNAGGVPSLHSTETAKV
VRAHGVESVIQFCGRDHDEPDLLREIESALDMGYRNFLLLTGDWLPNVERGVSQKTWFPM
DSLQMIHAVNRRLRDYQQRLGVVPFIGCASNPFSTPIEVSLRRLHNKRHAGARFSQTQAV
TNVDTFARWYEGLREGREAEARLTIPSIPLVGSQRMFEVLCRLPGVYVDPSLHAVMDNKD
HQQNALEWAFGIAEGVTENGAAGVHVMNFGMPPELIDAFLVEIRERGRAARSRYEKASA
>A0A3D5ULS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacteriaceae bacterium|TrEMBL
MEGKRLTYKEAVTSKDHFSVTWELVPGRGATEKAQDVVIETAKEAADDPRISAFTMTENP
SGKPAILPHVLATEVLKETGVETLVHFTCKDKNRNEIESQLHAMSRAGLQNLLVMTGDYT
TEGFKGRPKPVFDIDAVHAVKMIKKMNEGYEVPIRKGTKQLKPTDYFAGAVVSPFKATEP
EQMAQYYKMQQKYDNGAEYFITQLGFDARKFDEVRRYMKMNDINVPLIGNIYVLSMGVAK
LMNKNMIPGCVVTDQMLADLQKEKEEFENNKERQLLRSAKLYAVLKGMGYDGVTIAGHGM
TYEELCFILDKGEELLPEWESLVKEFDYPMENGFYYFEKDEKTGLNTDTPVDRSKTGHKK
NPLIDRLMFGTVHHVVLSEHAPFYPLAKKVCQRIDKGKLKKPFTWFEYYGKTFTNECRFC
GDCVMHEIGYTCPMSKCPKNQRNGACGGSRDGWCEVYPGTQKCIYVTMYEKYKAKDKEYT
MKLRYTPPVNWDLYRTSSWLNFFCERDYNYRKDD
>A0A838HFT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MPDFLDILSSRVVVCDGGIGTLLYEKGVFINQSFDELNLKDPSLVQEVHHEYAEAGADVL
ETNTFGANRLKLGLHGLESKVREINRAGVRNARAVAGTELLVAGSIGPLGEVPRFTGGLA
PSEMEELFREQAEAQAEEGVDLFVIETFASLDEMEAALRAVRAVSNLPVVAQMTFGDDGL
TLGGSSPDEVVVRLRMHAPDVLGANCTIGPKPMLDVITRLAAVHEGRLSAQPNAGLPESV
DGRLIYMASAEYLAKYAKRFVQAGVALVGGCCGTRPEHIRAMKHAVTPFTPRRSHVVAFP
EARTRRKPVEPVPRAEKSRLAALLAAGEEFVTSVELTPPTGFDLARLREGVRQVEAAGVH
CVNVPEYARVNPRLPPIAIARLLRPEFAVEPIVHYCCRDRNLTGMQSDLLEAEAFGIRNV
LVITGDPPKLGDYPKPTAVFDLDSIGLVKVAARLNQGLDAAGGRLAPPTGIHIGVGANPG
SLNMELELRRFRDKVAAGAEFVMTQPVFDADLLERFLGRAEDLEIPVLVGILPLHSYRNA
EFLHNEVPGMTIPEPVRERMRRAPGAEAAREEGVRIAREVLAQVRGFRGVRGAYIMPPFG
RYDLALQVLNGRG
>A0A6N6WJY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia madseniana|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRTQLASLKPKFVSVTFGAGGSTQQGTLDTVVEMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGAVGELRYASELVGF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFAHKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCGRLIDAKVPGLHFYTLNGAAATKAICERLGA
>A0A1J5J7L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeum sp. CG2_30_32_3053|TrEMBL
MYKITDIFKRKKKTFSFEFFPPKTEEGMKHLFETCDELKKYPDFFSVTYNPDGSSRERTL
FVVNEIQKKFKIPVMHHLTCINYNERTL
>A0A8D9YWC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus C427|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A1Q7TSC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon 13_1_20CM_4_64_14|TrEMBL
MPAEVASRPIRAGSRVERILAGGSFAVTAEIAPPASADASEIRRHAAVYRGTVDACNVTD
GQRALVRISSLAAAAIVLQEGVEPIMQMVSRDRNRIGLQSDLLGASALGIHNVLCLWGDP
PTAGNEKDAKAVFDLSTEEMIATFREMRDAGTLRGGDKVEQAPKVFIGAAADPFRGSKEE
SFGKLRGKVTAGADFVQTQGVYDVDAFEEWMRLVRKEWLHEKVYILAGVIPLKSAKMAQF
MIEKLGAVVPKHILDRMERAPNPKAEGVSIAVRTIKALKKIEGVRGVHLMPIGWEEVVPD
VVKQAGLLPRPDPKP
>A0A6I4SLY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontixanthobacter gangjinensis|TrEMBL
MSTPSIMPLDQMREAVTALDTPLFSGLPGDINASFEFFPPKTEKMEEKLWAAVQELAPLH
PSFVSVTYGAGGSTRERTHNTVARIIGEAGLPAAAHLTCVDASKAEIREVAEQYWEAGVR
HIVALRGDAGEPGAPFVPHPDGYKSAADLVSGLREIADFEISVAAYPETHPDADCPQSDL
DNLKRKLDAGATRAISQFFFSADTFFRFRDAVAAKGINAPILPGILPVTNVAQARKFAGA
CGAKIPPWMDGLFDGLDERPAARQLVAATVAAELCRRLYAGGVRDFHFYTLNRADLAYAI
CHMLGMRPKKGPQ
>A0A0C2Y496|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hebeloma cylindrosporum h7|TrEMBL
MKITQKIQQSHKEDKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPKEKVDIALKDAKQHGCRNVLALRGDPPQGKDE
WEAVEGGFVHGIDLVRHIRREYDDYFDIAVAGFPQHMTLPPEERDNEIRWLKEKIDAGVS
FIFTQMFYDVQLFIDWVKAIRAAGITVPIVPGIAPIQTWNGFQRATSLAKITIPQNFLDV
LEPVKNDDEKVREIGTKLVADMCRTILEADIGVRGLHFYTMNLERGTKMLLEELGLVPRI
ETIKPLPWRQSLTPSRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGHPTTFSDISSLFAKFCSSELSALPWSDQAPSVETSVISKQLA
QINELGFLTINSQPAVNGARSDDKVFGWGPSNGYVYQKAYLEFFVSPTLLEVLLSQIERD
SNITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGAQ
WAKLYEHNSPSQKLISEFMDTSFLVNVVHNDFHDADAIFRPFYKAGAEYLASKPKTTAVN
GH
>A0A349JT90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MNAQETKGTNALQKLIDDGRVHVMDGAMGTELYASGVFVNVSYDGLNLETPDVVETVHRN
YVNAGAEVIETNTFGANPVKLSSYGLADRTEEINHAAVGLARRSAQGRALVVGAIGPLGI
RIEPLAPTSREEAQEFYKRQVDGLVEGGVDGFVLETFSDLNEMEQAFKAVRSRSPLPVIC
QVTVGDDACTSYGTSPEDVATEVASWGASVIGLNCSVGPAVMLEAVERMAEVTDLPLSAQ
PNAGLPRAVGDRKIYLASPKYMAQYARRMIEAGARFVGGCCGTSPEHIRSIRALVGGVRP
PSTRARPDSHAESHDTPIQPEVPLGERSVWGRQIAEGTFVTSVEVTPPKGWNAEILLGQC
RRIQAAEANTVNVLDHPHAHTRMSALPAAMLIERKVEIETIVHYPCRDRNMTRMISDLLG
AAAAGLHNLLLVTGRPPAMGPYPDSTASLDIDSIGLTNVVHGLNRGVDPGGNAIGVPTRF
VIGVRVSQVAVDQDREAGRLNWKVDAGADFVITRPVFDAE
>A0A5D0QHX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea sp. PA05|TrEMBL
MALGRSSIRPDRVPTVREMLASGGRSFSFEFFPPKTDEGARQLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERIAHDTTLTPVAHFTAVNHSIRELRHLVGRFADAGVRNILAVR
GDPPGDPMGDWVQHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTEFFVR
KCRAGADYAITQMFFQADDYLRLRDRVAAEGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPDVAARFEAVKDDPAAVRRLGIEHGAELCQRLLDEGAPGIHFITFNRSSASREVFQRLD
RVTASA
>A0A5A9FFI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. Sh1|TrEMBL
MTAPISSLPSISFEFFPPKSEKMEQSLWQSIRRLAPLSPSFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGRYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDAYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPAKLAETFEGLDD
DPETRQLVAATVAAEQCQALQAQGVNDFHFYTLNRSDLTIAICRMLGVKAKAAPAAAAVA
G
>A0A3C0ZVX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sarcina sp|TrEMBL
LSGATIPHRFRAMVDRFGDDPQKMKQAGIVYAAEQIVDLIANDVSHIHVYTMNKPEIAAG
IQSSLSALWG
>A0A2L2MRU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces dengpaensis|TrEMBL
MALGSASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPSGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSEDWDLDVAHFVD
KCRAGADYAITQMFFHPESYLRLRDRVVAAGCTTPVIPEVMPVTSVKMLERLPQLSNASI
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQT
>A0A010IX92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 1542444|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A656JR01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. actinidiae ICMP 19096|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A505D6M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sporangiiformans|TrEMBL
MALGSASTRTDRARTVRDMLATGKTTYSFEFWAPKTEKGERNLWNSLRRIEAVAPSFVSV
TYGAGGSTRAGTVKATEQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWIPHPQGLNYAADLVRLIKEAGDFCVGVAAFPEMHPRSEDWDRDVAHFVD
KCRAGADYAITQMFFHPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PDALKERLLTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTASLEIYENLG
LHHSQQA
>D0RN29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|alpha proteobacterium HIMB114|TrEMBL
MKEELKFSFEFFPSKNAEDEVAAWKSLKKLESFDPQFYSVTFGAGGGERIKTDSFVKKIK
KESNVPVAGHLTCVDMSKDEINDIAVNWFEKGIKRIVALRGDVRKPGEQYKPHPDGYKNA
ADMTAGLKKLANFDISVAGYPEIHPDSKNKELDLDNLKRKVDAGADRIITQFFFDENIFL
KFRDDIAKQGIKIQLLPGIMPIQNYKRVKNFSNKCGTSVPAWIEKEFEGSEDNPDVQKMI
GSSIATDLVKKLQKEGVNEFHFYTLNKYELSYAVCSRLKSYKNFLKIKKEKEKGEIRI
>A0A368VK79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopolyspora algeriensis|TrEMBL
MSIQREVTESRRRRSDLVDLVRNISYEVMPFKSTEQDVLAAVPTTVPLTVTVTEAKGIDT
TLNLTERLLRHGYTVTPHLPARQFVDAGHVGDVVVRLREAGARSVFVIGGDAPEPAGEFP
DAYSLLQAMEAAAHPFDEVGIGGYPEGHAAIPQESIDLALKQKAPMATHVTTQICFDATT
TSSWAAGIANSDIDLPVSVGMPGPVSRQKLMRISAGIGLGQSARFLQKQQSLLWRFLLPG
GYNPTKLAKRLGTAVAGTTGNIRGLHIFTFNEIRKTETWRQELLASVADKGDRS
>A0A3S1TH28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.001.04.2.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A2T3FPZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium fessum|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPELCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A2V7M2E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
AVTQPVFDPAQLEAFLARVEQFKIPIVAGIWPLLSLRNAEFLANEVPGVSVPESVLTRMR
RAQDKGKEAALAEGVKIAREMFQQVKRTVQGVQVSAPFGKVEVALEVFG
>A0A847ML43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenaceae bacterium|TrEMBL
MSNIEREDSRFFSLEYFPPREQAGRERLISTTKQLLEIDPAYISVTYGAGGSTRSGTEET
IQMVSSLGCEAVPHLACVGSQPEEIVGILDSYKEKGIRKIVALRGDLPSGMGLSDSPLRY
AVDLVRLIREHSGDWFNIKVAAYPEMHPQASSFDEDLDHFVEKVNAGADLAISQYFYNAD
AYWDFVERVQAKGVDIPIIAGIMPITNYTQLARFSKMCGAEIPRWIAMRLESYGDDLESI
RAFGHEVVTRLCDELRSGGAPGIHFYTLNQAEPVLKIWRELEAK
>A0A6I8LI08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis camponoti|TrEMBL
MIERLRGDGPKFSIEFFPPRDAADEAVLWKAIRELEPYDPAYMSITYGAGGSSRDGTVRS
IARVATETTLVPMAHLTAVNHSVAELRNVIGWYASVGVRNILALRGDPPGDVYGEWIPHP
EGLTYAEELVQLVRELGDFCVGVSAYTYGHPRSSDLESDTKYLVRKLRAGADFAIAQLFH
DPEDFLRLRDRVAATGCDVPVLPGVMPLTTMRTLQSTIKLSGAPAPRKLLDRLEPLAEDP
KAFRAAGIDVTTELCEKLIAEGVPNLHFYTFNRSKATREVIARLGLVPARA
>A0A7V9VW66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexia bacterium|TrEMBL
RLPDGAPRPYLACMPNAGWPTQVGSRIVYRSSPEYFADFASLAAEAGVRLIGGCCGTTPA
HIAAMRPVIDRINSTDGHIEALPLAPSAARPAKTTPLIIMAADENTGIHNSIGKKFLKCV
EVDPPKGLNPQKSLDGARLLKSVGVDAINVADSPMARVRMSAMTLCYLIQHEVGVETIIH
FTTRDRSLMGLQSELLGAHAAGVRNILALTGDPPSLGDYASSSAVYDVDSIGLIRIIRQM
NDGVDFSGASIGRPANFTIACAVDPTKPDLEEEVRRLRTKIEAGADFVMTQPIFDVEVWT
DFLKRYGVERLPIPVMVGILPLQSSKHAEFLHNEVPGITLTDRARERMRRAGAQGRVEGV
KMAQGLLQELVPHAEGVYLMPSFGRYEVAAEVLDVLKDESVASAME
>A0A7Y6Q4I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. HO-A22|TrEMBL
MSPDYNPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNVMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLNEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRQPWKRETLPTDALVASRMEHIREGKEENQQEMAGAAAH
HPH
>A0A4R0DS09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4910|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQRLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQAENFDLDIQRFCDKANAGANAGLTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>Q2LUQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophus aciditrophicus (strain SB)|TrEMBL
MDLENVYEKSLKDPAVMTVTWELVPGRGAREKAQETVILEAEKAVRGGKISAISLTDSPG
GFPALMADCLAKEIKALGIEPLVHFTCKDKNRCQIESQLYALERAGVRNLLVMSGDYPVS
GFLGRPRPVFDLDPTHVLALIQDLNNGLEYPLPKGSGTLQPSHFFAGAAVSPFKETEAEL
LGQYYKLGKKITAGASFIVTQLGYDVRKFHEILKYMEMKGFDVPLVGNIFILTYGAARAM
KKNRIPGCVVTDELLAELDRERGLPDKGLEARLLRAAKMYALLKGLGFSGAHIGGPLVTC
EQVESVIEKGEELSASWQALIAEFQYSRPGGFYYFQKDPDSGLNKEIPVDVDSPAPDVSG
KGLYRFSVFCHNRFFEPGTKGFAFMHRIALTVKDSRLEKPLHKLEYLLKTLLYGCRDCGD
CALVDTAFLCPMSQCPKQQRNGPCGGSHQGWCEVYPDRRKCIYVKAYARLKADRQESRLE
TLQVPPCNWDLDSSSAWLNYFLGKDHTSRRLGIGKENVKPGNPG
>A0A4R2YNA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rahnella sp. JUb53|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRQIAEDYWNSGIRHIVALRGD
LPAGGGKPEMYATDLVQLLKEVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPKWMNSQFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEIALPV
RA
>A0A163BN26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus sp. MIT 1303|TrEMBL
MSEGHRDLSSALQRSIEAGAVTITAEVMPPRGADPVHSLTMAQGLKGFVHAINVTDGSRA
VMRMSSLALCRLLLDEGLEPILQLACRDRNRIALQSDLLGAHALGIRNLLCLTGDPVRVG
DQPEARPVHDYESVKLLHQVAAFNRAEDPVSGLLPDGATALFAGAAADPNCQSLSGLRRR
LERKKEAGARFLQTQMVMKPAVLEHFCNEVANPLGLPVLAGVFLLKSARNASFINRVVPG
ACIPESLVVRLEQASDPMAEGIAIAAEQVRSYLSLTQGVHLMAVKAEERIPEILDQAGIS
LVPV
>A0A109LVT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter sp. AP23|TrEMBL
MREAQRALETPLFSGLPGDIEVSFEFFPPKNAKMNETLWQSVETLAPLGPRFASVTYGAG
GSTRERTHQQVVRIQKETDIPAAAHLTCVEATREEVDEVARHYWEEGIRHIVALRGDPPD
GQSKYAPHPGGYANAVELVAGLKRVGDFEISVAAYPEIHPDSPDSQADIDNLKAKFDAGA
TRAITQFFFDPQCFFAFRDKAAAAGIEGEIVPGIMPVLSFAAVQRMSGLCGTAIPHWMEG
IFNGLDDRPEARKLVSATITAELCRRLYAGGVRQFHFYTLNRAELSYAICHMLGLRPKA
>A0A4Q3X864|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
VGIKCGFTIACAYNPNAIDQAEEDDRLRRKADAGAQVIYTQPVFDLGAMEKSVAMAETVG
IPVLVGLMPLKSSRHAEFMHNEVPGVRVPQDLRDRLGAAKDDAEGLEIGIASAIELRAEI
AHAAHGLYLMPPFGNAAIAARVLGGPGLPREVETTR
>T0FM64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira alstonii serovar Pingchang str. 80-412|TrEMBL
MKKISEIYGAAKGPVYSFEFFPPKTPEGDLKLMETVKELSRLDPDFVTVTYGAGGSTRDK
TVQILSEISKNYSLPTVSHFTCVGADRGQILETLKGIRSSGIVNLMALRGDPPKGEGEFK
KPEGGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVRNLKWKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGINVPVIPGIMPITSFSQIERFHSIAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGGSL
>A0A4Q3UP66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
VYTQPVFEGSIAEACAETCQKLGVPVLVGVLPLRSQRHAEFMHNEVPGIEIPRWLRERIS
SSADDAAALEIGVEEARKLSATIRGCAQGLYLMPPFGSAAIAERVMAV
>A0A1E3PJM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nadsonia fulvescens var. elongata DSM 6958|TrEMBL
MRISKKLEQAHAKEDKPTFSFEFFVPKTSQGVQNLYDRMDRMYGLGPQFIDVTWNAGGRL
SNLTTEIVDTSQSIIGLDTCMHLTCTGMPKKLVEDALRDAYNSGCQNILALRGDPPTDTE
KWQATEGGFSYAKDLVKYIRAEYGDYFDIGVAAYPEGTDEEPDVDLLIEHLKEKCDAGAD
FIITQMFYNVDKFLAWVTKCRAAGITIPIIPGIMPISTHASFLRRANWCKINIPQNFHDA
LEPVKNDDMAVRELGTKLVADMCQKMLDSGEIKHLHFYTMNLEKATIMVLEDLKIIQPNT
SANPPLPWRQSLALGRQDETVRPIFWKNRKQSYINRTQDWDEFPNGRWGDSRSPAYGELE
NYGRFLRYSSGQSQDLWGEPTSIKDIGNLFAKYVSGDVKSLPWSDSPISNEVELIKPQLI
DLNSRGFLTINSQPAINGVKSSDPVHGWGPKNGYVYQKAYLELLVSPKVLATIVERIGVD
GNLTYYSVNKDGELSFNVNDNSPNAVTWGIYPGKEVIQPTIVEKISFLAWKDEAFGLGEE
WASCYPSSSKSRELIDSIVNSWHLINIVNNDFHDQLGIFDIFEGLTAVEN
>A0A542ZJK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzihumus leptocrescens|TrEMBL
MAHGTASILPRAEHVTRSIPEVLAAEGASYSFEFFPPKDDAAEQALWEAIRRLEAVRPTF
VSVTYGAGGSTQDRTVRVTGRISRETTLTPMAHLTCVGRSVAQLRQVVGEYADAGVRNVL
ALRGDPPGGPGSPWTAHPEGLDHADELVALVKGLGTFTVGVAAFPDRHPESPSLDHDADV
LVRKADAGAEFAVSQFVFDADAWVRLRDRVVARGRDLPIIPGLMPVTNVRQVERMAQLSG
TPLPSAVVARLEAVADDPAAVREVGVQVATELAQRLLAEGAQGLHFYTMNRSTATLEVYA
NLGV
>A0A1E7IJB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium C00003068|TrEMBL
MLMKNILDQNTTSLSFEFFPPKTDLGWQRLFDNIAQLAPLNPSSVSVTYGAGGTTRSQTN
ELVLRIHRETGITVVPHQTCVAATKDDVHAILSHYQQNGIENVLALRGDKPQDVENWCPP
ENGFHHAADLVAYIRQHFPTMSIGVAGFAEGHPEMPNRLLEIDYLKQKVDAGADYIVTQL
FFENRDFYDFCQRCELAGITVPIIAGIMPLRNRQGMSRMAELAAGARFPAELLRRVYAAG
SEEEVEQIGIDWATEQARDLIANKVRGIHFYTLNSATATDSIYERLGLK
>A0A836B6I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlamydomonas schloesseri|TrEMBL
MKIIHKVQEKLKKGETFFSFEFFPPRTEEGVENLFERLDRMVAYGPVFCDITWGAGGSTA
DVTLDIATRMQNLICVETMMHLTCTNMPEEKLESALNEVKKMGVQNILALRGDPPKGQEK
FEAVEGGFSCALDLVKYIRKQHGDYFGICVAGYPEAHPDGIVEDAEQMKKNYWADIAYLK
QKVDAGGDMIVTQLFYDVDIFLQFVKDCRSVGITCPILPGIMPIMTYGGFKRMTGFCKTK
VPAEISDALEAIKDNDEAVKNYGIDLGVRMCRRLLESGEVPGVHMYTLNLEKSAVAILEQ
LGLIDTSRVQRPLPWRHVPAGTARAVEQVRPVFWSNRPKAYVKRTQDWDSYPAGRWGNTR
SPAYGALSDHQFMRRHSTNEARREKARAAWGAAPATVDDVKQVFVKYINGEVSTLPWSEL
EGGLTSEGAAIRDPLAALNANGYLTINSQPRVNGVASDDAVHGWGGPGGYVYGKAYVEFF
CSPAAWETMRAKLDAAPSITYLATTAAGSPAGNMAADAVNAVTWGVFPGKEVVQPTVVCA
ASFAVWKDEAFELWSSEWGALYEEGSASRQLMTTIKDSWVLVSVVDNDYVAGDLFRVLLG
>T3D9V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridioides difficile CD160|TrEMBL
MNINEYIKDSILVFDGAMGTYYSKLKNNAFNCEMANINDASTILSIHREYIRAGCKAIKT
NTFAANEILLECDFKTVKDIIQSGYEIALEATKNTDVFVFADIGPIPALNDRDLLSDYKK
IVDIFLEIGATNFIFETFSSDEYLPEISSYIKKKRPNSFILTEFAVNPEGFTRLGKSGTK
IFESISKNKDIDALGFNCISGPHHLLHFIKTIDINDSIVSIMPNAGYPTIINNRTFFEDN
SDYFSEQMLEILNQGVRILGGCCGTTPEFIKKTVDIINSSYIYENTIEKVLSPREKVKPI
SKNKLLEKLEIGKKIIAVELDPPVDTDIEFFMNSAKKLKDYGVDAITIADCPIARARVDS
SLLACKIKRELDITPIPHMTCRDRNINATKALLLGLNIENIDNVLVVTGDPIPSAERDEI
KAMFSFNSSILANYIKTLNENTFNTPFNIFGALNINAVNFDSQLKHAKIKIENGVTMFLT
QPVLTEQALLNLKKAKEILPVKILGGIIPVVSYRNACFMNNEISGITVSQNIIDMYKNTS
KEESTELAINISTQIAKEIEPYVDGYYIITPFKRIDIVCNIIANINK
>A0A497F0B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Verstraetearchaeota archaeon|TrEMBL
YYSKLMKALREGKFVVTGELEPVKTTDLTKVIETAKMLKPYVIAVNVTDNPTSYAYMNSL
VPCYIVQRDAGVEAIMQVTCRDRNRLAITADLLGAYALGIRNVLALTGDHVSFGDNPQAK
PVFDLDSTTLTLLLRKMVDEGVDLAGNKIENPPKFCVGVAASPGMEPLEVEILRLKRKAK
LKPDFIQTQSVYDMEVVKAFMKEVEKLNIPVIIGLTPIRSIGMLDYLVRNVPGIKIPEEI
QQRLRRAREVSKEKLYEENVEIFSDMIREIRKTTKAAGIHLMAVYFEWIIPKILEAANIK
SDWS
>A0A7Y3J4Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steroidobacteraceae bacterium|TrEMBL
MKFDDEPVPGYPLPILPGHTSPGRLERVLRAGGFAVTTELAPPDSADPQEVYARARVFDG
YVDAINATDGSGANCHMSSLAVCALLTRVGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NMLCLTGDGVQAGDHPQAKPVFDLDCVSLLGIARTLRDEHHFQSGRKISYAPRVFLGAAE
NPSALPHEWRAQRLAKKIAAGAQFIQTQYCYDLPLLRAFMRHVEDLGLLGKVFILVGVGP
LRSAKTADWMRKNVPGMHVPDALIERLAGAKDQAREGREICVELIKAAREIAGVSGVHVM
AYRQEESVAEIVDRSGALRGRVPWYPGRDEAGGTVNSPEDAPSMHRTTP
>A0A497N4V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MTEAFSNLMKEITKGKFVFTGELEPHKSTDLSDVLAWAKILKATGRIVAANVTDNPQSVC
TASSLVASYIVQKETGLETVYQLRASDRNRLALTSDLLGAAILGLKNVLALTGDHIKKGD
MVEAKPVFDLDGTQLIELIHRMVYEGKDISGNKIHGTPPQFNIGAAGNPNFKPLEIEVLK
LERKAEVGVDFIQTQVVFDVNTALQFLDAVKHINVPILIGVFPPKSYGQANYFDKHVPGV
RVPEELLEQFRRIKKITDKSERRKKINAYNIEYFTDFIKQVKKKQACKGIHLMAVGYPEV
VAPIIEKS
>A0A523WYQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MLCDPLEFSEMGKKRPAYSDLMKEIEAGRFVLTGELEPEKTTGLEEILDSARAMKPYVVA
ANVTDNPLAMAFMNSLVPSYIVQRDVGLETVYQMVIRDRNRLALTSDVLAAAYLGIKNIL
AISGDHTVLGDNKGGLSVYDLDSAQFVYLLHKMIDEGTDLEGNEIHGKVPINVAIAANPN
ANPLEPEILKIGRKVKLGTDFIQTQTMFDIDLTKEFLKETEKFNCPTLVGIFPLKSFGIA
DFFDKYIPGVSVPKDLLESMRKCKDEPDKEKRKDLYDEVNIEFFAPFIKEIKKTTKAAGI
HMMAVLYERIFEPLLAETM
>A0A2N2NYU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-2|TrEMBL
MSERIKFIKGLAQEKPIISDGAMGTVLHQRGIRFDECFDHLNITHPAQVADVHHAYIEAG
STMIQTNTFGANHYKLSQFGLEHKVAEINQAGVELVRRVAMASFRDIIIAGDVGPLGVRL
APFGRVQLEDARIAFKEQIQALIDAGVDVIIIETMTDFYEVREAILASKEINPDIPIIAS
MTFTRDDRTLLGDTPEKVATSIYNSGADVIGINCSGGPLQLLRILKKMKTAVPNGVYSVM
PNAGWPEQQDGRIMYPAGPEYFGDYAISFWQAGAKILGGCCGTTPKHIQAISRIIQDTKS
SDIAFGLEIPEMQIEREAEKEAPKSELSQKIDANQFVFAVEMDPPRGLSTKKLLAGASLL
ADSGADVINVADSPMARMRMSPWAVCSLIQRYVGVETVLHFPTRGRNLLRVQGDLLAAHA
LGIRNVFVVMGDPTAIGDYPEAMDNYDLVPSGLIKLIKESFNIGIDHAGSEIGQPTSFFV
GSALNLNSPSPEIELKNHLRKRKAGSDFALTQPIFDAKSALEQLRWFREQAGDPNLKILV
GILPLATDRHAAFLHNEVPGIIIPEEIKIRMRKAGDKSAEEGIKIAVELIEAMKAELQGV
YLMPAFNRFDYVAEIIETVKKKTQP
>A0A1V5PKV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium ADurb.Bin363|TrEMBL
MKNKFLDCLHCGGVVIFDGGMGTEIYRRGIYINRSFDELNLSNPGLILEIHKDYINSGAD
VIQTNTFGANLYKLKPYGFSDKVKVINYEGAKIARQAAGHTVLVAGSIGPLGVKLEPWGT
VSLKEAREAFKEQAQALLEGGVDLFVIETFSDLGEIHQAISAVKEICDLPVVAEMTIDNQ
GNSLFGTPPEVFVPRLDEWGTHVIGINCSVGPQVMLEVLERMVHLTDKPISIIPNAGVPV
NVEGRNIYLCSPEYMATYAKHFILSGAKIVGGCCGTEPEHIHAIKKAVIALRPKKSVVKV
EKIEKEEKKINPVPRCQKSAFAKKITEGQFVTSVELLPPRGYNARNVINASKYLKEQGVD
VINIPDGPRASARMSPLCLAVLIEEKAGIETVLHYCCRDRNLLGMQADILGAYSLGLRNI
LIITGDPPKMGTYPDATAVFDVDSIGLTRLVSCLNHGYDLGKTSIEKPTGFFIGVGVDPN
ALDPDYELRHFDAKVEAGAEFVITQPVFDVDVMENFLPKIEHYNIPVIAGIWPFPSYRNA
LFMQNEVPGVTVPEEIMKRMKKADEEGRAMEEGLLIARETLQKLMPVIQGAQVSAPFGKY
KLAMDVIREVKCEKK
>A0A6P0PC59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO2F5|TrEMBL
MNRFRNAVKSEEFLVTAEVAPPKGADPTHMIEMASTLKGRVHAVNVTDGSRAVLRMSSLA
ASIILKNNGIDPICQVACRDRNRIGLQADLMGASALGLHNILALTGDPVKAGDHKDARSV
FDMESVRLLQMIAKLNQGIDWNEKTLPDGATDLFVGAAVDPQSPSWSGLKKRFERKLLAG
CQFFQSQLISDFDKLEKFMNQIAVDSNKPILAGIFLLKSAKNAAFINKYVPGVDIPEHII
NRLAKAEKPLEEGIKIAAEQVQIASKICHGVHLMAIKREDLIPRILDMAEISPIGE
>A0A397N542|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. AG209|TrEMBL
MPAGTSSQADAFINAFSLEVSAKAMPALRAEAARIPRGTVISLPWLASEDDDARLVAARM
VRELGFEPMPHLSARRIGSHAALERFLERAASEAGVTRCLLVAGDLATPAGPFADSASII
QTGLLEHFGIKVVGIGGHPEGHPVMSADDRWQVLGRKCQAIEARGMAPLIVTQFAFDADT
VLAWLDALRARDISVPVLVGVPGPASITRLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDCLVKGLTGAHGPISPHFFPFGGIAPSLEWIAQYQRRVRGSGR
>A0A1W9IJP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium SG_bin9|TrEMBL
MGATSSTHPDATQGSKRPAISYEFFPPKTEEMERNLWETIKRLAPLKPSFVSVTYGAGGS
TRERTHSTIARILKETDLTPAAHLTCVDASRGEIDDVVASYYDTGVRHIVALRGDPAAGI
GTAYQAHKDGYQSSADLVASIKRRYPDIEVSVSAYPEKHPESHNFDADVDMLKAKVDAGA
DRAITQFFFDNNLYNAYVDRVRARGITIPVVPGILPVQNFKTAKSFATRAGATVPSWLED
KFDGLDDDPETRKLVAATVAAGQVQKLFKNGVENFHFYTMNRADLVFAISHLLGFRANGS
QKAA
>A0A0M1J318|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromatium sp. WMS3|TrEMBL
MPDKNHQIFSFELFPPKTAEGLEKLKTQVAKLNKVEPRYFSVTYGAGGSTRDRTFATVDW
LRSQGIETAPHLSCIGSQHQEILDILNRYKSQNIKRLVALRGDLPSGMGAKDAGDLNYAN
ELVTFIRKETGDLFHIEVAAYPEIHPQAHTAQLDLQHFQRKVQAGANAAITQYFYNADAY
FAFRDECTRLNIEVPIIPGIMPIINYTQLARF
>A0A5E8EQ44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.043.05.1.1|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFVDFGVTRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>A0A0D6KRC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolypothrix sp. PCC 7601|TrEMBL
MPDTQIPTVLNAFRSAAQAGEFLITAEVAPPKGGDPKHMLDMAATLKGRVHAVNVTDGSR
AVLRMSSLVASAILLQHGIEPICQIACRDRNRIGLQADLMGTHALGIRNILALTGDPVKA
GDHPDAKGVFDLEAVRLLQLIRNLNQGVDSNEQPLSDGALDLFVGAAVDPQCASWSGLQS
RFERKLQAGAQFFQSQLITDFERLEKFMDKIAAGCNKPILAGIFLLKSAKNAQFINRCVP
GVNIPQHIIDRLAKAKHPLEEGVKIAAEQVQIAQQLCQGVHMMAVKREDLIPQILDLAGV
KPMNLVLTK
>A0A5E8EMP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.043.05.1.1|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAQRLDHILHDEITETQVDMVK
TAH
>A0A378TMR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium tokaiense|TrEMBL
MSVSNVGSRTLSVVDRIAEVGRDRVPFSVEFYPPRDAAAEARLWRAARTFEPMGPAFVSV
TYGAGGSTRDRTVRVVGELTEATTLLPVAHLTAVGHSVAELRAMVGAYADRGIHNVLVLR
GDPQGGVHDEWVKHPDGLEYAVEMVDLVRRLGDFHVGVASFPEGHPRAGGLEQDTANLVG
KLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPLIPGIMPITSLRVLRRQCELAG
SQIPVALLDRLTAAAGTGAEEDRDEVRKVGIELATEMSARLIAEGAPCLHFCTLNFARAT
GEVLANLGMMARV
>A0A0U1KX70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa ovata|TrEMBL
MFPKCSFSEALADPEQLSITWELVPGRGMREKAQEHLLKMAELAAKDPKINAITITDNPG
GKAAILPYSMAVEAKRLGIEPLVHFTSKDKNRNALESELYALGRADIHNLLVMTGDYPTA
GYAGHAKPVFDFDAVHALRMITKMNEGTYTNLPATHFFAGAVVSPFKATEAETMAQYYKL
HKKIANGARFIITQLGYDARKFDELRKYADSNQFNVPLIGNIYVLSVPVAKLMNKNLIPG
CVVTDKLIKKLEAEQADTANKKEQQLFRAAKLYAVLKGLRYDGVNIGGHGLSYDDVQYII
EKGEEQSGNWQDIAVTDFDYPQADGFYFFEKDVTTGLNTCQPFDRRQTGSAHSSLKQSVM
DLVHGVAFDHKAPLYPLNKAVAKFIDNSCLKKPFTIAEYTTKTITNECRFCGDCAMHELG
FICPMSQCPKQQRNGACGGSRDGWCEVYPEQQKCIYVKMYEGFKGRGKEERMKAKYMPPC
NWELHRTSSWLNYFNDRDYNNNKD
>A0A7C6N739|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MGKCVFYDKLIKVCFYTKIFSGGTALKITQIFKEKKPLISFEVFPPKPDYPIETIYRTLD
ELRDLAPHFISVTYGAGGGNRRRTVEIASRIKNEQKIEALAHLTCIRHSREEIDEISRRL
FAEGIENILALRGDPPAEGQGIFDFTYARDLILHLRRLGAFCIGAAAYPEGRPDTTDIAV
EIRHMQEKVAAGADFFITQLAFINDHVYDFLDQLVKKGISCPVFIGVMPVYNTRQIRRIT
ELSGAKIPRELNSLLEKYVDSPADAEKVGIDFAVKQIADLLAHGVDGIHLYTMNRARQTR
EILRRLGKPVS
>A0A8H7UV74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor plumbeus|TrEMBL
MKVIDKIHKSEQEGRPFWSFEYFPPKTPQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
DLTTEIVATAQSVYGLETMMHLTCTNMPVKQIDDALEAAKNCGCQNILALRGDPPKGQAN
WESCKEGFEHADDLVRYIREKYDDYFCIAVAGHPEGHIDNPDKEDDLLQLKKKVDAGADL
VVTQLFFDIDSFLTFYKKARAIGITVPILPGVFPIQNYTGLKRVISFNNNFVPQKIWDDL
EPIKDDDTAVKEYGINLTVEFIKKFREVGINGFHIYTFNLERSSRLILERLSLMAPVESI
KPLPWNPSLTSKRAKENVRPIFWKNRAKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
INLKYPVEQCIEMWGNPTTVDDIAQTFARYCKGQIAGIPWSAQQLDAETDIIRQRLAAIN
LLGYLSINSQPAVNGVKSSHSVYGWGPKNGYVFQKAYLEFFVSPEKLDELIEKVAKNPQV
TYYAVNKQGDLRTNTQSDEPNAVTWGVFPGKEIVQPTIVEAVAFMAWKDEAFELWNRWAR
IYERESESAELILDITKSWYLINIVHNDFQDENGIWRLFDLEIDGEISRKLLQSNTVAR
>A0A7L5Y691|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MNALPLSFEFFPPKTPEGAEKLRAVRQRLYALAPEFCSVTYGAGGSTHEGTFATVREILA
EGQGAAAHFSCIGATRERVRAQLAELQAMGVRRLVALRGDLPSGYGLGGEFQYASDLVAF
IRAETGRAFHIEVAAYPETHPQARSPEADLQAFAAKARAGADSAITQYFYNADAYFRFRD
EALRLGVALPVVPGIMPITSATQLLRFSDACGAEVPRWVRLRLQAFGDDVESIKAFGLDV
VTALCERLVQGGAPALHFYTMNQSAATLEIARRLGLAPAGA
>A0A840HLY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. ERR14|TrEMBL
MTDLTIPARADGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTPYASHPDGYQSSPELIAGIKKRHGDIEVSVSAYPEKHPEARDFNDDIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARAFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A540VYJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora acidiphila|TrEMBL
MTSRPSAARSPRRLRDLLAAGEPTYSFEFFPAKDAAGERDLWAAIRRVEAVRPTFVSVTY
GAGGSSRDRTIATTERIAAHSTLLPVAHLTAVGHARAELRAIIRRYADAGIRDVLALRGD
PPGDPRGAWQPHPQGFQHAAELVQLLKESGSFTVGVAAFPERHPRSPDWESDIRHFVAKC
RAGADYAITQMFFRVDDYLRLRDKVAAAGCATPIIPEIMPATAYGQIRRFAELSNAAFPA
ELAARLADARGDAAAGHRIGVEHATRMADRLLQEGAPGLHFITLNRSTAALEIYRNLGLD
QPVESAA
>A0A564Q9L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanolliviera sp. GoM_asphalt|TrEMBL
MTDEVYSDLMREFKEGKYVFTGELEPEKAGNVNEPIEMAKELLGLVVACNVTDNPQSFAY
VSSLAASYKIQKETGMECVYQLRCSDRNRMALLSDVLGAGTLGIKNILALAGDHVSLGDT
PDAKPVFDLDSTTLIHMIRKMVDEGKDLGGNDIEDPPKLHVGGAAAPGAAHLKAEVGKVK
RKVNAGVEYLQTQVVYYTDVLDKFFNELGKIDVPILVGIFPARTFGQADFFDKYVAGVDV
PPDYLENMRATKQIKDKEKKKEEVDRVNIEFFTGFLEHLKGTPAAGCHMMAVGYPRIIPP
LKKLME
>A0A523USZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division TA06 bacterium|TrEMBL
MQPFREFLKKNLLLFDGGNGTEFYKRGVFINRCFDELNLSDEAMVTDVHKQYIEAGAEAI
ETNTFGANRLKLSKHGLDDKLFEMNHRGVEIAREVTQGRAYVAGAIGPLGIRIEPWGKTA
REEAREIFKEQAKALLEGGVDLFLLETFLELSPLEQAVLAVREICDLPIIAQLTIREDGS
TPFGTPVEMYTKEMSSWDVDVIGLNCSVGPEAMLEAVEAMAARTEKPRSTMPNAGKPKEI
EGRNIYLSSPDYFAEYARRFALAGVKVIGGCCGTTPKDIRAAKAAIKALKPVEHGGQWKQ
VTVEAAPVKLVPQVEKSGLARKISKGEFVEVVEITPPRGCDPSKVLKAAKALMEAGIDAV
NIPDGPRASSRMSPLALATTMERETGIESVLHYCCRDRNLLGMQSDLLGAYTLGIRNLLL
ITGDPPKLGDYPDATAVFDVDSIGLVNVVNRLNHGRDIGDNAFGDPTGFFIGVGVNPQAH
NLDYEIRRFWYKVDAGAEFAITQPVFDPEALLSFLEKISHCRIPIIAGIWPLASLRNAEF
LRSEVPGIYIPDSVMERMKKAEEKGEAAREGINIARESLLEVRDSVQGVQVSTPFGKYER
AIEVIKAMRDDE
>A0A7C9LAY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella vespertina|TrEMBL
MHNQFIDIEQLLRDQSGEKHFSFEVLPPLKGNGTESLFSNIAKLKEFNPSFINITTHHSE
YVYHEREDGLIERQRIRRRPGTVAIAAAIQQRYEIPVIPHVICSGATKEDIEYELLDLQF
LGVNHLLLLRGDKAREDRMFTPTENGHSHTTELIEQVNLFNKGVFIDGSEMKNPGAPFTY
GVACYPEKHEEAPNIEEDLRYLKQKQELGATFAVTQLFYDNKKFFDFVERARSIGITIPI
VPGIKPFAKLSQLTMVPKTFHCDIPEELASLAKECKTDEEARQLGIEWATQQVKELYAHG
FNNVHFYTVSAVKSVHEVVSRLLK
>A0A7V8BMH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MYALRLWAVRHAGAVEALYRAMQRAFDVLRPLVRRIGFERVERPAAALERLVKGALFDCR
MCGACVLSSTGMACPMNCPKALRNGPCGGVRDDGGCELAPQMRCVWIEARQGASRMRAGA
LPAQPNPPLEHQHVGRSSWLRVLKQQPWPAAQVTEAPVRDEIVCGSRLEALLRGGHFVVT
SECSPPDSADARDVVARTRHYAGWVDALNVTDAPGAHCHMSSLGVSLILQREGFEAVMQM
TCRDRNRIAIQGDILAAAALGIHHLLCLTGDGITNGDDPGAKPVFDLDAVSLLDTARRLR
DDGQYRSGRRLSARPRLLLGAVDNPFAPPYDERPLRLARKIAAGARFVQTQFCFDVAMLE
RYMVAVRAEGLHRRCAIIVGIGPLTSARAARWMRERVPGVHLPESMVARLERATDPAAEG
MRICVETIRRIRAIDGVAGIHLMAPRREHLIGPIVEASGVLAGRPAPVQAQGDMPCPLPA
>A0A8E1RLL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. 50588862|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1K0FIR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Couchioplanes caeruleus subsp. caeruleus|TrEMBL
MSLGLPSRLPTSPAIGELIRRPTPTFSFEFMPPKTPEGEQLLWRTIRELEPLRPDFVSIT
YGAGGSTRDTTVDVTERVASETTLLAMAHLTAVGHSIAELRNVIGRLAGAGIRNVLAVRG
DPPGDPNGEWVRHPEGVLYAEDLVRLLREAGNFSVGVAAFPYKHPRSPDIDSDTRNFIRK
CRAGADFAITQMFFEADEYLRLRDRVAAAGCDTPIVPGVMPVLRMATIARSAQLSGAPFP
PALLKRFERIADDEAGVRRLGIDLCSEMCRRLLDEGVPGIHFITMNRSPATREVWQHLTG
AAAAPAAA
>A0A7I8MP14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis associated proteobacterium Delta 3|TrEMBL
MIVAEKKPIQEIIEEIKTHDSVLILGCNECVTVCEAGGKKEVGVLASALRMYFLNKGRDM
RIDEHTLERQCDHEYLDEIREMIDQYDGVVSLACGVGVQFTAEKYTQKPIYPGVNTFFMG
VTESRGVWTERCQGCGQCILASTGGICPVSRCAKRILNGPCGGSTTGNCEINKDVACGWQ
LIIDRLKALGRLDEYEELAPIKDWSTDRAGGPRKVVREDVQS
>V2Z7K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Catonella morbi ATCC 51271|TrEMBL
MKVSQVYKEKKDKKVLSFEIFPPKKDSELKNIDETLAVLCELKPDYISVTFGAGGSSNCN
RTIELARKIKHEYHVEPVVHLTCLHYNKAEIDEFAKVLSDAGLENVLALRGDKNPNFPEK
DDFKHASDLIAYMKERWNFCFLAACYPECHPESDGVVNEIKHLKTKVNSGAEVLLSQLFF
DNDIFIRFQENCKVADINVPVIPGIMPVINAAQIKRMITMCGAAFPLRFQKIIHKYEDNK
EALFEAGMSYALSQIIDLLASDIDGIHLYTMNNPLVARKICEGIRKII
>A0A1Y3RJT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor sp. An9|TrEMBL
MKIIDILNQDRPTLSFEVFPPKTSDTYDSVAKATQEIAALRPDFMSVTYGAGGGTSDYTV
GIAAGIQQQYGVDVLAHLTCASSTRDHVAQVLEHLKEKGIQNVLALRGDIPEGGAPAHDY
QYAAQLVRDIKAHGDFCIGGACYPEGHPESPTKNADIDHLKAKVEAGCQFLTTQMFFDNN
ILYNFLYRIREKGITVPVVAGIMPVTNGKQIARICKLSGTYLPERFKAIVDKFGDNPAAM
RQAGVAYAAEQIIDLIANGVEHIHIYSMNKPEIAASIQSSLSEVLK
>A0A355BJ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MTYLRDKITQGKFVTTVELEPPKGTNTDRILHYALTLRDLVDAVNITDSPMANMRMSPIS
VAHILRGNIGLDTIFHLTCRDRNTIGLQSELLGAAALGVRNILALTGDDPKKGDHPSARG
VFEVDSVGLVHIASTLNQGFDLAGNRLDQAPQFHIGVAANPCADDLEREIDRLLVKIDKG
AHFIQTQPVFEAEQLAPFLNKLPQPCIPVIAGVLPLKSYRMARNIARNIPGIHIPAWLMK
SMETGGRAEGIRVAREFIAELPWLAQGVHIMPVGDA
>A0A5M6HVF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastochloris sulfoviridis|TrEMBL
MTLSSCRPSRFVGGPGISVSFEFFPPKTAEMDVQLWDSITRLAPLRPAFVSVTYGAGGST
RERTHAIVKRIVEETALKPAAHLTCVAATREEIDEVIGAYWAAGVRHIVALRGDPPAGPG
TAYAPHPGGYAHSTDLVAGIKRIADFEVSVSAYPEKHPESASIEADLDVLKAKVEAGASR
AISQFFFDNAHFLRYRDRVAARGLHIPIVPGILPVMNFKQAKSFAERCGTEVPSWMARRF
EGLDNDPRTRELIAAAVAAEQVLDLVDHGVTEFHFYTMNRADLVYAICHLLGLRPVSAQA
AA
>A0A2A3YK64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium alimentarium|TrEMBL
MSATTTLPELERTAPVRHRPALSYELFPARSDVSFERLRETIRHLEATAPDYVSVTSRAG
HGNFARVLEVTEHVLAETALRPLVHLTSIGSTRAQLTTIIHALLDRGVRGILALRGDQPE
GHRLEDDEIPFARPLVELIREIERERTATLAGGRVSIGVAAYPHRHPESATTSHDTEVLV
AKERAGADFAITQVFFDASAYCRLLERAQTAGIRLPLVPGFVPATNPRRLERLAEMSGVE
APRDLLHQLEIASDDVERRRIGVRFTVDLARRVLDAGAPGLHLFTFNSHGDALDVLDHLD
LDRWSTTQGETR
>A0A0E3RSH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina mazei C16|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRFSASLEDASQLKGIADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDYPTCGDHPGSKP
VYDVDSVQLIELVRKLDTGVDFAGNKLDGGTSFCAGAVSGIDPEKTMQLIKLQKKVKCGA
DFIQTQAVYDIGMFEEFMDAVNYLEVPVIAGLIPLKSLGMAEFMNKNISGIHVPEEIMLR
MKDASSPMEEGLLIASETIKELTKLSRGIHVMPIGSHRNTARLLSLAGISQK
>A0A6G4VGE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces scabichelini|TrEMBL
MALGSASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWIPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSANWDMDVAHFVD
KCRAGADYAITQMFFHPESYLRLRDRVDAAGCETPVIPEIMPVTSVKMLERLPKLSNASF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A7W6XUJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium esperanzae|TrEMBL
MVLKSDARGRNIRVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTRAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRQQTKSAGAAA
>A0A1G0WUS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium RIFOXYC2_FULL_35_21|TrEMBL
MSKTFFLNRLKEGVVLFDGGMGTELYNRGVFINKCFEELNLTNPSLVKQVHDDYRKAGAE
VLETNTYGANRFKLKPYMLADKLYDLNYQGAMIARSAAGDDVYVAGAVGPLNVRIEPLGP
ISREEAREYFKEQIKPLMDGGVDLLIFETFVYPEELKQAVIAAREICDLPVIAQMTIDED
GCSLTGAEPEVTIKELENLGADVIGVNCTVGPQVMLNWLERTRKHTSLPISIMPNAGKPK
NIDGRNIYLTSPEYLGEYAKHYIQSGANVIGGCCGTSPEHIKRMRNTLNSFKPLIAAPKI
EISKVEEFPDIEIIPQEKKSRLARRLKENHFVKFVELVSPHGVSAHKEIEKAREMNYYGI
DVINIPDGPRASARMSALSLAVQFQREVGIETVLHYVCRDRNVIGMQSDLLGAYALGIKN
ILAITGDPPKLGNYPDATGVFDVDAIGLVNILNRLNHGLDIAGNPIGKPTGFYIGVGANP
GAINLDEEIKRLDWKVDAGAEYIVTQPVFDLKVFETFAKRIEHFKLPLIAGIWPLTSLRN
AEFMNNEIPGCSVPDSIMKRLEKVQDNKEASNAEGIKIAREILKSLLKSIQGVQISTPFG
RVQSVIDVLEGIEV
>A0A3R7EI98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Syntrophoarchaeum sp. WYZ-LMO15|TrEMBL
MGEAFSELMKKIKAGEFVYTGELEPHNLSTDISDVVEWAKTLKSIGKIVAANVTDNPQSF
SAMTSLAASFIIQRDSGLEMIYQLRTADKNRLALASDILAASALGLRNILALTGDHTHMG
NTPDAKPVFDLDSAQLVDLIHHMVYEGVDLAGNEVQGPRPQINIGVAGNPNQEPLEIEVL
KMERKVEVGADFIQTQVVFDLDIALTYLDAIEHLNTPTLIGIFPPRSYGQAEFFDKFVSG
VTVPPEFLEAFKKFKQISDKAERKKKIDEFNIEYFIDFIKEIKKKKNCAGCHIMAVGYPD
VIAPIIEGVEK
>A0A7S8A9E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. CCBAU 53351|TrEMBL
MSGAMTDLTTSARADGQDGHLKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVT
YGAGGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRG
DPAGGIGTPYASHPDGYQSSAELVAGIKKRHADIEVSVSAYPEKHPEARDFDDDIDTLKA
KVDAGATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRAGTTV
PDWFAAKFEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLG
IRAKSAQKAA
>A0A3N5APC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermodesulfitimonas autotrophica|TrEMBL
MAVSKFQEVLNSGKFVVTCEIGPPKGTNLDKMQHHIDLLKYRVDALNVTDHQSSVMRFPS
LGGCLAIKERGGEPILQMTCRDRNRLALQADLLFAYTRGIRNVLCLTGDAVVIGDHKGAK
GVFDLDSVQLLRAIRQLETGEDLGGNKLDGAVEFCAGAVVCPEADPIEPQLIKFEKKVEA
GAEFFQTQGVYDLEKFAKFMEFARQFPVKILAGIILLTSVGMAKYMNANIPGICVPQYLI
DELAAAGKGGALRKGIEIAGRMIATIKKERLCDGVHIMAIGREELVLEILEAAGI
>A0A2D9B594|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp|TrEMBL
MKVTEHIEKSHGKTQFSFEILPPLKGENIQSIFDAIDPLMEFNPPFIDVTYHREEYVYKE
LDNGLLQKQVVRKRPGTVGICAAIQNKYDVDAIPHILCGGFTQEDTENFLIDLGFLGIDN
VMALRGDAVKSETYFKPEKEGHHYASQLVSQIANLNHGVYLDEEVQNNTPTDFCIGVAGY
PEKHLEAPSMDSDIYFLKKKIAKGATYIVTQMFFDNSKFFQFVEKCRKEGIEVPIIPGLK
PLVTKKQLNLIPHRFNVDLPDDLIREVVKCKDNDQVREVGIEWCLQQSKELVKAGVPVLH
YYSMGKSVNIKKIASQVF
>A0A376FH90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter asburiae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTPVELYRSS
>A0A3B0AV02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. CGR2|TrEMBL
MSSEIETSGTARVPFSFELYPPRSASNEEALHETVRRLAAAGPEFLSVTYGAGGSTGGRS
LDVLRFIREHTDVEPLAHLTCVGNTYAGAAALIREFLDAGILSFLALRGDPPLGQTEGFL
GDLESAAQLVQLIDRAQAERAPYEESPVPGFPGAARVAPRRKVNIAVAAFPKGHPRATHR
AQEFEALLAKQAAGATFAITQLFFHPDDYLAFVERARNAGVTIPILPGIMPITSPARLAR
VLELTGEDLPSELAIALDVEPTTEGRRAIGIEWAARLTRDVVAGGAPGVHLYAFNQHDTV
LTVLSDAGILPALRH
>A0A2N5J9N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium margollesii|TrEMBL
MHVPQFSLEVFPPKRDAPVGTIYDTLDGLEGVNPDFISVTYGHGTHSDRTATARIANTIR
SEYGIPTVAHLTALYSDRDVVDQALDMFDEAGVFGVLALRGDVIEGQSEVGAFAHASDLV
AYIRDRRPNLKIFGACYPEGHIECPSLDEDIRNLKIKVDAGATNLISQLFYDNEDFLRFV
DKARAAGIDAPIEAGIMPVTSARSVRNMAKKNATVIPKSLDAMLEKWGDDRESLRRAGII
YASQQINDLVAQGVDGVHLYTMNHPGTTRRIWRNVAPLFQEV
>A0A0J9FPQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. 3_1_13|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAADINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A0N1MDA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. RIT-PI-q|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLANFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A328Y277|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia unamae|TrEMBL
MKPIELSFEFFPPKTPDGIEKLRATRAELATLKPKFVSVTFGAGGSTQQGTLDTVVDIAK
EGVEAAPHLSCIGSSKESLRAILGEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVAF
IREETGDAFHIEVAAYPEYHPQARSPRHDLEAFAQKVKAGANSAITQYFFNADAYFRFVE
DAKKLGVDIPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTDLCRRLVEAGVPGIHFYTLNSAAATRTICQRLGY
>A0A1F9L1P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYC2_FULL_48_10|TrEMBL
MSELKSGSNLEKVLKAGHFAFTGECGPPKGANVEHLKEKLSHLVGKVDSVNMTDNQTAVV
RMSSWAGSILMMEQGLEPNFQMVCRDRNRLAMMSDILGAYALGVRNMLCLSGDHQSFGNH
PDAKNVHDIDSMQLISMVKKMRDEGKFLNGEDIDVAPKMFIGAAANPFADPYEYRPYRLA
NKIEAGADFIQTQCIFNMEKFRDFMKKVVDMGLHERCYILAGVTPMKNAGMANFMSKYVP
GMDIPESLIKRLKGVDKRDQAEEGIKFALEQIQEFKEMKGVAGVHLMAIEWEHKVPEIAE
RAGVLPRPKV
>A0A7K2U0T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8358|TrEMBL
MTGAADEGLRAALTRSTPTFSFEFFPPRTAAGGRALWNAIRRIEPLAPDFVSITYGAGGS
SRDRTVEVVRRVVTETTLRPVAHLTAVGHSAAELRRVVGRYADAGVRDVLAVRGDPPGDP
RGAWSAHPDGFTHAYELVELIRSLGDFTIGVAAFPERHPRSTDWESDIRHFVAKCRAGAD
YAITQMFFDVEDYLRLRDRVTAAGCDIPIIPEIMPATDVRRISRFVELSGCAFPEDLAHA
LEAARDDPAAGHRVGVEHATAMAERLLAEGAPGLHFITLNSSTAATDIHRTVAPARPVPP
AGTGAVRGALPAGGAPVGLPGQA
>A0A8H7E5W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endocarpon pusillum|TrEMBL
MHISSKLAASYEASKPTFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFIDITWGAGGRHS
QLTCEMVNAAQTHYGLETCMHLTCTDMSKEKVDQALQQAYKAGCTNILALRGDPPRETEK
WKATEGGFRYAKDLVSYIKSRYGNHFDIGVAGYPEGCDDQDDVDLLIDHLKQKVDAGSTF
IVTQMFYDVDIFLAWVKKCRERGINVPIIPGIMPISTHASFQRRVDWTRCHVPDAWNAAL
EPIKNDDAAVREIGKGLIADMCRKIIDAGILHLHFYTMNLAQATRMILEQLSLTPTTSGS
PLFKPLPWRQSLGLNRRDETVRPIFWRNRNTSYVARTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANTKLWGQPSSLQDISGLFVRYLNGKLDRLPWSEAGISPEADSIKEELL
SLNERGLLTINSQPAINGIPSNHPVHGWGPANGYVYQKAYLELFISPNLIETILERIIAN
KDLTYYAVSKNGELRTNTRDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAYRLGDD
WSRCYPAESSHRRLIEGLMNEWFLVNIVNNDFHQEKEIFRIFDGLQVDDMDKVIEGQPCT
NGVQSNGTPEEAKQDRPIEANGTVVEMNGSAERKPKPYTGAEFTGASQLRN
>A0A738DXX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Abortusovis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7W6A9X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas pseudosanguinis|TrEMBL
MTNTILTRAEAALAHEEPLFADVGGDIAVSFEFFPPKTEKMDAQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTMDAAAHLTCVEATREEIDQVAQEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPDSADQQADIDNLK
RKIDAGANRAITQFFFSPEAYFRFRDAAAAAGITAEIVPGILPVSNVAQTRKFAAMCGAR
IPDWMDRLFEGLDDHPGARQLVAATIAAEMCRRLYAGGVKGFHFYTLNRAELAYAISHLL
GVRGKKAEAVVAA
>A0A6N7CV90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. T7|TrEMBL
MTFDSVRGRASEGWVTRTPSIVDRIRSSGDGRVPFSVEFSPPRDEAAEARLWRAVREFER
MGPAFVSMTYGAGGSTRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRG
ISNILVLRGDPPGDPLGEWEKHPQGVEYAEELVRLVRDLGDFHVGVASFPEGHYRAPDLA
HDTRYLVSKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDAEQGAKPIIPEIMPITSLGSV
RRMLELSGSRLPAHLEKRLATAAGDGPEENRAAVREIGIDLATEMSERLIAEGAPGLHFI
TLNFARATSEVLARLGDKVGSGVADPAPVTPAPVS
>J4H1L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibroporia radiculosa|TrEMBL
MRITQKIAEYNDKTHPFYTFEFFPPKTDQGFENLLPRISRLASLEPLAINVTWGAGGSTK
ERSLELAAITQTQHGIDTILHLTCTNMEQGMVDDALTNAKARGIHNILALRGDPPRGEEY
WIPTDPRFTYGVDLVSYIRSSPEFSSEFCVGVAAYPDGHPDRETDDDGELEHLKAKVDAG
ADFIITQLFYDVDGFLQWMKKVRSKGIQIPIIPGIMPIQTYASFLRMTKLCGTRVPPHLM
SDLVLLRHDDQKIKDYGVDLAVKMIKRLTAESDIRGIHLCTLNLEKSVTRVLGSLAWIGG
SSKPMNQLIADVPSGPESQFVITPHNATDSATNSLVVSGPIAEGEVGKGELNNAATWDDF
PNGRFGDFKSPAYGETDLWGSSIMSRHQTLEQWGHPTTTSDLTNMFLRHLHSKIATTPFS
PTPLSLESLIIIQHLERLTRKGWWTVGSQPAINGASSSDEIVGWGPRGGYVYQKPFVEFF
ADAADLKKIEKKVEEEGYGWVDYFAGNVQGECRTNVPEGGRNAVTWGVFPGQEVTQSTII
ERESFLSWKDEAFSIWAEWASFYPPNSQERILLERIRNERWLISIVHHDYMKPSALWTFL
VDGETLV
>A0A0Q4L6U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf38|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGISFEFFPPKTEKMDTQLWEAIRTLEPLAPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGDPNADIDNL
KRKLDAGASRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKSDVTVAAA
>A0A0S8D2L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira bacterium SG8_3|TrEMBL
MAKSFEEALASGNFLVTASIDAPKGTDLEDAARLIDKLKGILDALGVSDNPCAAMRMSPW
AVCRLVLEKGVEPILHVACRDRNRLALQSDLLAAASLGIHNILCVSGDHIKFGDHEDAKP
VHDIDSVHLLAAAKAMEEGRDITGNALRGTAAFCLGAVANPEADPVEPQLIKVDKKIKAG
ASFLVTHPVFNMENLKQFIEHVRQSHVKVFAGVRLLVPEEVAHYRDGSCPGLFVPEKLLE
EIQGADIAKCVGIAANMVKEIKSAALCHGIHITAPGHEEKIPDILKAGGIEAGS
>A0A3A5M3F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter cheniae|TrEMBL
MIDVPVRVEVIPGKDLVERLRTHLAAPAVVTVTCLPHHGPREAVEVAVQLADAGYTVIPH
LAARSIGNRADVGRYVAQCLDAGISDVFVIGGDAAEAAGPYAWSGALMEDIAELSAGALG
MGIAVYPEGHPATGDEELATALRAKQELASWCVTQLCFSQQTLRAYPARLRRDGVTLPVW
AGIPGPVRMSRLLRLAGNIGVGQSLGFVKRSAGGANTGSVVRQLLSSASYDPAPLVDALD
GAGYEGLHVYSFNDLAELAASGLTGAPA
>A0A1F9L3I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYC2_FULL_48_10|TrEMBL
MRVTDLYKKKKPVISMEFFPYRDEKTAENFKTTIDELSAAHPDYVSVTFGAGGSTKDGSF
QTVKTVFKDKHMPCVAYIAGYGLSPDNIIAVLDSYKNLGIETIFVIRGDRPREKDFVPHP
DGFAHASDLISFIRKRYDFTLGCAGYPEGHIEAQSLEKDIEFLKLKVDNGAEYIVAQYFY
DNDYFFNYLEKCQKAGIEVPIIPGIMPVYTLKMTQALSKVCGTKITSALQQKMDAVGAED
PGAVLKLGIDFAVDQCRGLLKQGVSGLHFYTMNRSRSTLDIIHQLQGESLF
>D6Y9E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / KCTC 9307 / NBRC 14880 / R51)|TrEMBL
MTMTLGLPSRLPDRAPTVRELLAAGERSFSFEFFPPKTGEGERQLWRAIREVEALRPTFV
SVTYGAGGSTRDRTVEIVERLARETTLTPVAHCTAVNHSVRELRHLIGRFADAGVRNMLA
LRGDPPGDPLGEWVKHPEGLEYAEELVRLIRQSGEFCVGVAAFPNKHPRSPSIESDTEYF
VRKCRAGADFAITQMFFRAEDYLRLRDRVAAKGCDTPIIPGIMPVTKLSTITRSEQLSGA
PFPRDLAARFEAVADDPEAVRRLGIEHAIELCRTLLDEGAPGIHFITFNRSSATREVFRA
LQPATVGS
>A0A2T4BNM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma citrinoviride|TrEMBL
MHIRSLVADTEKSGAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLEKVNDALQKAYKAGCTNILALRGDPPRDQTS
WKAADGKFQYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGAGF
IVTQMFYDADNIRWVGKVRERGITVPILPGIMPIATYASFLRRAKHMQCRIPPDWMAKLE
PVKNDDVAVREIGKTLVADLCRKLLANGIHHLHFYTMNLAQATRMVLDELNWTPSPERPL
KQALPWKQSKGFGRRDEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDAY
GIGLTGTNESNRKKWGEPQSVQDIATTFVQYLEKKIETLPWSESALAAEADPIKDDLVAL
NKRGLLTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLMPPYLLDEMISRLDDFPN
LTYYAVTKNGELKSNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGVDWA
HCFDAGTPSRALIEDIMNNWYLVNIVNNDFRENNTIFALLEGLEVKDLAVPASGTTSGTA
>A0A4Q8LGE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas winnipegensis|TrEMBL
MTPISFEFYPPKTDEQRAQLNRTAERLARYAPEYVSCTFGAGGSTLSYTAETVRHLKQHH
GFDAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHAGDLRYASELIAFI
RAEHGDAFQLEVGAYPETHPQASDALSDLKHFKAKVDAGADAAITQYFYNADAYFGFVEA
VRRLGVEIPIIPGIMPIANFAQLRRFSEQCGAEIPRWIAKRMAAFGDDAAAVKDFGADVV
AQLCQRLIDGGAPSLHFYTLNLAKPTQTVLQRLGIR
>A0A4V6A9K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Populus alba|TrEMBL
MKVIDKIRAAAGAGDANGNGGDSCSNNKVVFSFEFFPPKTDDGVDNLFERMDRMVSHNPS
FCDITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNV
LALRGDPPHGQDKFVQIQGGLACALDLVKHIRSKHGDYFGITVAGYPEAHPDVIGSDGFA
TPEDYHKDLAYLKQKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGISCPIVPGIMPINNY
KGFIRMTGFCKTKVPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTL
NMEKSALAILMNLGLIEESKITRPLPWRPPTNVFRVKEDVRPIFWANRPKSYLTRTIGWD
QYPHGRWGDSRNPSYGALSDYQFMRPRARGKKLLDEWAAPLKSVEDIYEKFKVYCLGKLK
SSPWSELDGLQPETKIINEQLGKINLKGFLTINSQPAVNGEKSDSPSVGWGGPGGYVYQK
AYLEFFCSKDKLNALVEKCKSFPSVTYIAVNKGGSWISNVALTDVNAVTWGVFPAKEIIQ
PTVVDPTSFSVWKDEAFEIWSRGWASLYPEGDPSRTLLEEVQSSYFLVSLVDNDYIHGDI
FAVFADL
>A0A4Z0F048|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella suis|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATCEDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A8F9ZVG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella sp. ESL0441|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGISFDKAEMQKILHDLKCAGIDNVLALRGDINPNIAPKDDF
RYASELVSYIKENGDFNVIGACYPEGHLETSTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYTFLDKAHDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQDVDGIHLYTMNNSYIARRISEAVSTLLAVPKSA
>A0A2M7AEN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium CG07_land_8_20_14_0_80_59_28|TrEMBL
MGNFVLGEHRQRNNRPRWPPDGWKALPADVPSLRRSAARQVACAASLAPVRRVGSIIPTV
RRNGTLVFRPSHTLQGADTPTSGVHPIPHMQNNESCSALEARLRRGDFVVTVELLPPRGP
SFDSIYPQLEVVKRHRLTVAAVNVTDNASARVRVSGLAACKVVIDEGLEPVFQVACRDRN
RIAMQSDLLAACAFGVRNVFCVTGDFVTFGDDPEAKPVYDLDSIQLLHVYNRIRQTGRLS
SGVEVRETSRSELVTPKFFLGATENPFSDPVEVRVRRLHKKQQAGAQFIQTQCIFDTDRM
ERFMELVCEQGLDKELHILGGIMPVKSHRPLEFIRDNIPGIRVPDALINRMKNAKNAEME
GIEVAAETVESLRSMSGVSGIHLMTVRWHAAIEHLLIRSGLTQTNELQPTP
>A0A6A8Q6F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneolaceae bacterium|TrEMBL
MKVTEHIAQSDGTLFSIEVLPPLKGQNIRSLFDHMDPLMEFEPPFVDVTYHREEFIYKKR
GNGLLERKTVRKRPGTVGICAAIQNHYSVDAVPHIICGGFTKEETENALIDLNFLGIDNV
LLIQGDTRKPEREFVPEPNGHEYASELIEQVVNLNNGVYLDDDLENAKPSDFCIGVAGYP
EKHYAAPNMDTDLKYLKNKIDTGGDYIVTQMFFDNQAFFDFVEKCRDYGIECPIIPGLKP
ITTKRHLNILPQLFHVNLPVELTKELETCTTNDAAKQVGIEWAVQQSKELIEFGVPILHF
YSMGKSRSVYEVARELF
>A0A8J3UFC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planotetraspora silvatica|TrEMBL
MALGLPSRLPERVPTVRELLAAGERSFSFEFFPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLIGRFADAGVRNILAVR
GDPRGADPLSEWVKHPEGVLYAEDLVRLIRQAGEFCVGVAAFPYKHPRSATIESDTEFFV
QKCRAGADYAITQMFFKADDYLRLRDRVAARGCDTPIIPGIMPVTQMSTIARSEQLSGAP
FPPEVAARFEAVADDPAAVRRLGIEHAAELCRTLLDEGAPGIHFITFNRSSATREVFEAL
APATATVRR
>A0A8D5JV86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloradius palustris|TrEMBL
MTQPIISFEFFPPKTVEGIAKLRETRKQLALLNPKFFSVTFGAGGSTRDRTKDTVFEIQG
EGYEAAPHISGISSTKAEISALLDTYRSNGIKRLVVLRGDLPSGEASAGDFRYANELVQF
IRQTSGDAFQIEVAAYPEFHPDARSAASDLQHFKNKVDAGANAAITQYFYNPDAYFRFMD
QCQALGIDIPIVPGVMPIYNFTQLSRFSDVCGADIPRWLRLRLQDYGDDLPSLRAFGVDV
VAELCQELLAGGAPGLHFYTLNQAGIISQIASQLDLTKL
>A0A2D7D7H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kiritimatiellaceae bacterium|TrEMBL
MARTQPRIRPMSLLEKIQHQPLIGDGAMGTMLYNQGIFINTCYEQLCLTQPDLIRNXHQQ
YVNAGADLIETNTFGANRIKLQAHGLADQLEAINRAAVQLAHQSKQPNTHILASIGPLLT
SDQLFTDRHTHELEQLFHEQMSILADEPIDAFQLETFTHVDEAELAATIAKTYNLPVFVS
VTVGKDGETRRGETIEQIIRQLDASPAVDALGINCGLGPAAAFSIAERALPLTQKPFTVS
ANAGLPQEVDGRLIYMSTPEYFSEYAKRLIELGVRLVGGCCGTTPEHISTMAQQIKSLTG
VKQHIQITQHQQQETPPVEAISTAEKCRFGAKLKAGEKVTSIEITPPRSIDLQPMLDKCR
QCHDAGIDAINIPDGPRASARISPMVAALAIEREIGIETVLHYCCRDRNLIGMQSDLLGG
YAGGLRNYLIVTGDPPKLGDYPDSTAVFDVDAVGLTQVVNNLNHGIDVGGNPVNPPTGIL
IGVGANPCAVEPERELNHYLNKINAGAEYAITQPIFDPEALLRFLDAADARGATIPVVAG
VWPLVSYRNAQFLKNEVPGVEVPDTLLERMSHAKTKEEGRALGIQIAREIRDKIADRVAG
FQVSAPFGIVDLALQVLD
>A0A891SLU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O157:H-|TrEMBL
MNFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8J3B100|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pilimelia anulata|TrEMBL
MIRSAAPTFSFEFFPPKTAEGERQLWSAIRELEPLRPSFVSITYGAGGSSRDTTVAVTER
IASETTLLPMAHLTAVDHSIAELRHMIGRLADAGIRNVLALRGDPPGDPMGEWVRHPDGL
LYADELVRLVRGAGDYCVGVAAFPYKHPRSPDIDSDTRHFVAKCRAGAEFAITQMFFEAE
EYLRLRDRVAAAGCDTPIVAGVMPVTSMRTIERAAQLSGAPFPPALGARFAEVADDPVAV
RRLGIETAGAMCRRLLDEGTPGIHFITLNRSTATREVWADLGVTAGA
>A0A6B8YVH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei subsp. paracasei|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A3B9TTB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MATAIEQIQAAAANWSIEVTPTGATKIESFRDCLNEGTTVNVTFLPGTDPADTIAVCERL
HNDGMKPVPHLAARSLRNADQLDELLTAYTSRCGVEEVLCIGGGVDDPVGDFTATMEVLK
TGLIQKHGIRHIGVAGHPEGSPDISDDEIAEALGAKNELARAEGLDLYIETQFCFEADIV
LDWERRVRAAGNALPIRIGIPGPATIKTLFRFAQISGIGPSMRFVAKQAKNVAKLMTVQS
PHLLIAGLAEGMAADGDCLIRHFHFYPFGGFARTATYAGAIADGKIEMLPKGGFNVTEG
>A0A1S7P1B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium tomkonis CFBP 6623|TrEMBL
MHKLLDISASSIIPASIEASPAQVLGPASLAGLFPQGVRVYLTDTGAASQVRLVDAARHL
RDLGYEPVPHLAARRIPSRVEFEEQVKRLAGEAGVSDVLVVGGGVDRPAGPFASSMDMLS
SGIFDRYGMKQIAIAGHPEGSPDFSEETAVAALRLKRDFAQRSDATMRIVTQFGFDAARF
IAWAEGLVASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTTLAKGHS
PESVVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVNRGSWQTGGADRSASPDSVAV
>A0A355Z758|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium|TrEMBL
MRVIDHLRSNPGSTAFSFEILPPLKGNSILKVYNIIDKLREFEPKYINITSHRSEMIFKE
MPDGSFRPQKMRKRPGSVAIASAIQNKYGITAVPHIICKGFTREETEYALIDLNFLGVHD
LLLLRGDTKGPEKSDDPAKLNLHATDLQQQVNNFNLGIYADGERFEANETPFSYGMACYP
EKHEEAPNMESDIYYAKQKVDAGADYLVTQMFFDNEKYYAYVKRCRKAGITVPIIPGIKP
IVFKNQLNVLPKIFRSEIPEPLAAELRGCESDAQVKEVGIEWCIAQCRDLMANGVPSLHF
YTLMASDSVRRIAQAIY
>A0A3M1PIC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSPHSYNPRAFAPSLFAGIGGDITVSFEFFPPKTPAMEDQLWEAITTLAPLKPRFVSVTY
GAGGSTRERTHRTVQRILKETPLTPAAHLTCVNATRDEIDAIARDYWALGVRHIVALRGD
PPERGQRYRPTPGGYANAAELVAGLK
>A0A1C5PY17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Coprococcus sp|TrEMBL
MRIIDKIKADGVHISFEVFPPKTDAGFESVLKATDGIAELTPSFISVTYGAGGGTSKNTV
KIASHIKNDLKIPALAHLTCVSSTKEEVHKVIGQLQKEGIENILALRGDIPQDGQFPLPG
QYSHACELIEDIKKMGDFCIGAACYPEGHVEMEHKKDDIRYLKEKVDCGVDFITTQMFFN
NDIFYNFLYRIREQGIMIPVLPGIMPITTKKQLARSCALSGTAVPQRFRAIVDYFGDDPA
AMKQAGIAYATDQIIDLIANGVRNIHVYSMNKPEVAAAIMQNLSEIVK
>A0A537U0Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MRVSFEFFPPKTEEMEKTLWESVTRLAPLQPNFVSVTYGAGGSTRERTHSTVKRILAETA
LTPAAHLTCVAATREEIDSVIRNYCTVGVRHIVALRGDPLGGLGDRYAPHPGGYCNAADL
VAGIKRLSDVEVSVSAYPEKHPDSPTVEADLDMLAAKVEAGATRAITQFFFENDLYFRYL
DRVRARGIDVPVVPGILPVQNFKQTKAFAARCGASVPDWLAERFDGLEDDAATRKLIAAA
VAAEQVLDLVDRGVTDFHFYTMNRADLVYAVCHLLGLRPNQETDALPLPIVEKERA
>A0A2A4LJA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MNKQLNVSFEFFPPATEKMEEILWKSVRRLEVLKPRFVSVTYGAGGSTRERTHKIVTQLA
HTTSMVPAAHLTCVDASRDEIDEIVQNYWDEGVRHIVALRGDPKAGIGEKYIPRPDGYAN
AEALVKGIKQIGDFEISVAAYPEQHPESGSLRADLDNLKAKIDAGATQAITQMFFDNEQF
YRFLDECEKAGIDVPIIPGIAPVINFKGTVKFAKMCGTSVPRWLHRRFDGLDDDEETRRM
VAASVVVEQVRDLYAYGVRDYHIYTMNRAELTYTICHQLKNIG
>A0A3A9GM64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. 1XD42-69|TrEMBL
MKIAEYLKHHRLVMDGAFGTYFEACFPEESGVAELCSLTAPEKVKKVHRDYIKSGAKLIR
TNTFAANTMFLSDLEQVKLAVARGYELAREAAELGEEIFVGADIGPIYDTGFLGKEVVLQ
EYKEICDTFFSCGADIFVLETQTDFAYLKEITEYIKSRGDVFVLVQFAVDKSGYTRDGIS
LEKIIEKAAGMDTVDAYGFNCGVGAAHLFRLLKHAAFPNEKYVTALPNAGYPLTLRGKTL
YGDSREYFVDTMEQVAGLGVDILGGCCGTTPEYIRALRERLESVPRGKKKIAKREEKVLP
KVQSCFLKKISAGVMPFIVELDPPFSADFGKVLKGAEILKHAGADLITLADSPMARARAD
AGKLAAKIQNELEIPVMPHIACRDKNLIAMRSGILGDYMNGLRHFLVVTGDAVARDQRGS
VTSVFDFNSISFMEYLSRMNEDVFGEEPVFFGGALNYHGANPDAIIKRMEQKIENGCGMF
LTQPIYSGEDIERIAYIKGRTQTKIMCGIMPLVSYKNAVFMANEMPGIRVPEDVILRYRQ
DMTREEGEEAGIQCALSIARGLKDIADGYYFITPFNRASMIARIIQQLKQEI
>A0A7X0U2Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea rubra|TrEMBL
MALGRSSIRPDRVPTVREMLASGGRSFSFEFFPPKTDEGERQLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERIAHDTTLTPVAHFTAVNHSIRELRHLVGRFADAGVRNILAVR
GDPPGDPMGEWVQHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIDSDTEYFVR
KCRAGADYAITQMFFQADDYLRLRDRVAAQGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPDVAARFEAVKDDPAAVRRLGIEHGAELCQRLLDEGAPGIHFITFNRSSASREVFQRLE
RLPASA
>A0A2D8SWW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MDVASLYRNAPGGLPFSLEILPPNRGLGLNXIHDFFNNLHEWLPAFVSVTYHQAHKIDII
DDNGQMEQIWNRKKPGTLGVCAMLKFQYGLNVIPHVICGGFSKFXSEDFLVDLDYLGLKH
IXALRGDPNKTETQFNPHPQGYAYANELVEQIVDMNAGKYVEDVKEARPTDFQIGVAGYP
EVHAEAMNLHDDVTNLKRKITSGASFVITQMFFDNTCFFQFDKXCREMDIHVPLIPGIKV
ITSKRQLEVLPEIFGTKLPKKLVDDVMACETDEEVCQVGIAHAVNQTKELLEYGXVGVHF
FTMNNSQVFNXVLQQFQE
>A0A842HSA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp. 7-48|TrEMBL
MGSPVMAIDCDSVPDNLVHCFSIEMTGKDIDALQAAAPLLPPGTSVAVTFLPGENYETRI
AACKAVRDLGFEPMPHFSARRIQDEAEFHDFLHAVVAEAKVRRCFVIAGDAAEPEGPYAD
SMQLIASGAFEAAGIDLIGVAGHPEGHPNMTAGEATAVLRAKTDEIERRGMAALIVTQFT
FDAARTLDWLAEVRQAGIDVPVLLGVPGPAGIKTLLRFAARCGVGASASVLSKYGISIGH
LLGSAGPDRFVDALRAGIGEQHGHVRLHFYPFGGLDKTARWIADYARKHLEHHHHHH
>A0A8F8GV71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter hormaechei|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYATDLVGLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A534J197|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MRRPFRTSLASTPLVLEIVPPSRRASEKAISTLVDRVRDAVASLGNLDGLNLPQVLDENH
QGQPFLRNMDPRDFVQRLGSDLGVDPIVNNVVAHVPSANAFRRWARESLDKFGLRSFVLV
GGTSSRVRYPGPTVLEANRILRSAAEGHNEVALGNITIPDRENEVDRLIEKTRAGCDFFT
TQVLFEAEPMATVVRAYGKRCAAQGMKPATVLLSFAPVSDYQDLEFLAWLGASVTPRTEE
ALSGSEEKALGRSSIELARTLWSHLLAAALQSRPAVPLGVNIEEVSLHNFDLAVQMAREF
PSWRDAKSPRADHV
>A0A534KYV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MPAEVASRAIRAGSRLERILASGVFAVTAEIAPPASADASEIRGHAAVYRGTVDACNMTD
GQRALVRISSLAAATIALQEGVEPIMQMVSRDRNRIGLQSDLLGASALGIHNVLCLWGDP
PTAGNEKDAKAVFDLSTEEMIATFRALRDTGILRGGDKVEQAPKVFIGAAADPFRGSKEE
SFGKLRAKVTAGADFVQTQGVYDVDAFEEWMRLVRKEWLHDKVYILAGVIPLKSAKMARF
MVEKLGAVVPKHILDRMERAPNPKAEGVSIAVRTIKALKKIEGVRGVHIMPIGWEEIVPD
LVREAGLLPRPDPTP
>A0A6M8AXU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces marmotae|TrEMBL
MSTTPDDSAPAPHGAPTLSLELFPPRAGAASSQTWSALDRLLATAPDFVSVTYRPTFVLG
ARPADPAVRVIREHNPAEDVVTHVLARSRTPLMAHLTCIGYRKRDVVEIVRLFLALGVRR
FLALRGDPPRGHDADELPGELAHAEDLVRVIREVEAEYFDDGERHLTIAVAAYPAVLDHG
RGVEVLAAKQAAGADLAITQVFYDPEDYLSLARAATYCGVSMPLLPGILPMTDLARLSRL
AALTGVPIPAGLAASLKPARGAQAVTRGIDATLRLATEVLDGGAPGIHLYTFNRTRPALD
VVSQLRLGGILGGERASAAMQRDVRRAYLNATPGGDRRMPEPAHAGPARP
>A0A1G3AJA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RIFCSPHIGHO2_02_FULL_38_41|TrEMBL
MIQNRSDIKSGSNLENLLKTGKFVVTAELGPPRGADRSAIEKKCEILKGYGDAFNITDCQ
TAVVRMSSIAASRIVLEAGLEPIIQMTCRDRNRIAIQSDLLGAAALGAKNLLCLTGDHQK
FGDHPMAKGVFDIDSVQLIQIVKTLRDEKKFQSGQELKTSEPRFFIGAAENPFADPFKFR
AIRLAKKITAGADFIQTQIIYNVKKFKEWMKMVTDMGLHERAFILAGVAPLKSAGMAKHM
KYNVPGMDVPDEVMNRMTAASANKKGKEEGIKICLEVIEQVRAIKGVAGIHIMAVEWEEA
VPEIVQQARLYPRPTI
>A0A1M6ENX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium cavendishii DSM 21758|TrEMBL
MEIKKLFDDKKVVFSFEIFPPKVTSKVEVIYETLATFSYLKPDFVSVTFGAGGSASDNKT
TELSSLVKNKYGIETVAHLTCVNSKVSDIDCILENLKHNGILNILALRGDIIDKQNLGEF
KYASELISHIKQKGNFSVSAACYPEGHIESTSLEQDIINLKEKVDSGADHLISQLFFDNN
VFYKFLDETSKKGINVPIQAGIMPVTNKKQIERIASISGAKIPPKFLKILDKYENDKEAL
RDAGIYYAVEQIIDLISSGVKGIHLYTMNSPYVARKVTESIEHILSSINNKNIR
>A0A126T571|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas denitrificans|TrEMBL
MNISFEIVPRSLEAFDEQYGFVQTLDKGINIINVPDIQRFDTRSWELATRVDRSKYRFIP
HFRAIDFKIESGELYRIIEDYALDSVLLVSGDPPEGLKRSFYNTDVVDLIRAVRQRFPSL
HIYAGFDPHRSGVQDECDYIQRKVDAGAGGFFSQPFYDSRMIDIYAEHMLDLETYIGISP
ITSKASMNYWEVKNKVKFPKSFRPDYDWNVEFANGVIASAAANGLNVYFMPIRIDLARYF
GEIKLGG
>A0A4R3AH12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. JUb20|TrEMBL
MKIVDHISNAKGKTLFSFELLPPAKGQGIQSIFKTMDALMEFKPPFIDVTYHREDYMYKK
HESGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDPDFIPTEGGHAFATDLLQQVADMNQGQYLHEDIAISEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVNKCRENDIHIPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSEAVSGCKNNADVRQVGEEWLVQQCKELIDFGAPVLH
FYTMSNPGPTKSIVEKLF
>A0A3R9LV29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus cristatus|TrEMBL
MVNRQTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLAE
FISNDLEIPTIAHLPAVYLTKEMVSNILQALDRVGVNQILALRGDVFPDVAPKDDFKYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRT
AGLAYAVDQIVDLVTHDVAGIHLYTMNNAATAYHIYKATHALFNHTPSVQSF
>A0A1M5F501|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum mesophilum|TrEMBL
MKVIEHLEKANGRSLFSFEILPPLKGDTIESIFKNINPLMEFNPPFIDVTYHREEYVYKE
LGDGLLKKQVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPEKDGHAYASELVTQIEDLNKGRYLDDNLQNSSKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKNGANYVITQMFFDNQKYFEFVKKCREEGIMVPIIPGLK
PISTKKQLNLIPHRFKVDLPDTLVKEVVNCKSNAEVRQVGVEWCIAQSKELQQKGVPILH
YYSMGRSTNIQKIAEGVF
>A0A564ZF96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methylomirabilis lanthanidiphila|TrEMBL
MKIADLYGTDRFGLSFEIFPPKTEAGEVPLLSALTALKVYRPSFVSCTYGAAGTTREQTL
ELTVKIRTACGVTTAAHRTCVGSTVEEIRQWLKQASDLGIENIVALRGDPPKGQAEFTKP
EGGLAYANELVALIRQEFPHFSIAVAGYPETHQEAPSPAVDLANLKRKVDAGADAVITQL
FYDNRDFFDFRRRYTEAGMTTPLIPGILPVVNLGQVQRITSMCGARIPISFLAELEAYRE
DPHGQVDVGVRYAVRQCRELLDAGVPGLHFYLLNKAEATSRILQALDLPR
>A0A1X7UHX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amphimedon queenslandica|TrEMBL
MESERVSLPSLPHSEAPFYHVWSNGSVSSGVPTSPSSSSGQGNTPRSHSPLFSSSSLIDK
IQSRIDGGDKFFSLEFFPPRTPAGASNLIARFDRMFSGGPLFCDVTWHAAGDPGGDKETS
SVNIANAALNFCGHETMLHITCAEYSKDEVKAHLTKAKNLGIKNILALRGDLPDNWMPKP
DGFSYGTDLVKFMKQEFGDTFTICVAGYPHGHPDCPDYLEDIVHLKEKVDAGADFIITQL
FFETSTYLKFYRDCREVGIKVPIIPGILPIQGYQSLRSLTKLSKLEVPHNIREAIQPIKD
DDAAVRSYGVHLAVQMCRELLDSGVVNGLHFYTLNREVAVVDILKQLGLWCEDPLAMKAL
PWKQSGNSKRRCSEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGASESPAFGDLKDYYLF
YLCLRSKPETCRAMWGEELLAVSDVHHVFECYITGQKNKNGVKVTSLPWNDEELAIETSL
IVAHLAHVNRHGVLTINSQPAVNGASSSDPVHGWGNNGGYVYQKAYLEFFASREFVASLI
EVLPSYPWVNYHIVNKEATMNITNCNPHNAIAVTWGVFPGKEIIQPTVVDPVAFHYWKDE
AFTIWHTHWANLYPQGSQSRSLIDHIQNTYCLVNLVDNDYIRGNQLWSLIDDVLVNTGAI
TERFNPEQFTTSR
>A0A5N5QMZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceratobasidium theobromae|TrEMBL
MSVMKFSEKLANHTSDVPYFTFEFFPPRTEQQGLSNLLTRISGLASLKPVAVSVTWGAGG
STRDRSLDLAGFCQADNGLDTILHLTCTNMEKGMIDDALTTAMDKGICTVLALRGDPPRG
EEYWIPTDPRFQHAEDLVKYIKEHPTFSGHFCVGVAGYPDGHSEGGSEEEQLSYLKRKVD
TGAEFIVTQLFYDVEKFKSWLRKVRNHGITVPVIPGVMPLQTYATFIRMTELCKATVPKH
IQANLDAIKHDDQLVKEYGISLAVSMIRSILVDGDVKGVHFCTLNLEKSVRKILDELGWT
HMLVQPVNQIIIDATQSPHILPSPDNPPHPTAFTISPSEATQHAAFSLAEHHRAGIVRTQ
AEAVDRGWDDFPNGRFGDSKSPAFGVDDPWDGGGLGVPPHAAVAQWGHPTTEQDLTTLFL
AYLKNEAQTTPFSPTPLSAESETILPHLISLTSRGLWTVASQPAVDGAPTSDPVVGWGPR
GGRIFQKSFVEFFAGEEDLNKIARAVEDSGEGWVTFFAGNNEDGFLTNIPDSGSNAVTWG
VFPGQEIAQPTIIDRDSFLAWKDDAFMIWYDFGRCYPPDSSTRKLLESVSQTRWLVSIVH
HDYKSPNALWDFLAEHLK
>A0A7V6DPB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans|TrEMBL
MTMTAGSNLEKVLRAGHKAVTCECGPPRGADADHFRKKATYLKGYADAVNVTDNQTAVVR
FCSLAASKILLEMGIEPVMQMVTRDMNRIGLQSNVLGAAALGIKNLLCLTGDHQSFGDHP
QAKNVFDLDSTQLLNTVRMMRDEGKMISGTEVEGRPAMFIGAAANPFADPFEFRVIRMAK
KINAGAQFIQTQCIYDMERFGKFMEMAVDMGLHEKCYIMAGITPFKSVGMANYMKKFVPG
LSVPDEYITRLKGVPKDKQAAEGIKIAVEQIQQCLEMKGIAGIHLMAIEWEEKAPEILEA
AGLHPRPKVD
>A0A1J1D2H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sporogenes|TrEMBL
MHIKELFNQKNLVFSFEIFPPKATSSVKTIYETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTSEDIDSIINQLKENNIENILALRGDIPKDKNIIGE
YNYAFELIRKIKENNNFGIAGACYPEGHIECESLEKDIRELKRKVDAGAEHLISQLFFDN
NTFYEFLNKAQQNNINIPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDRYEYDKEA
IRDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARRITESTKSIFNSINKDVAV
>A0A841T602|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella thailandensis|TrEMBL
MLKHKIDNREAGILTYGLTPPKTNHEPDKIAEIARKQIERIRDIGLDGLVLYDVQDEADR
TDQDRPFPYLSTMDPTEYSKEYLGAFDVPKIIYKVVGKESPEELAKWVADNEKEDRYSVF
VGASSSKQAVTMRLPDAYGLAKEGNPRLRFGGVVIPERHKAKGDEHLRVAGKQQSGCSFF
ISQATYDVEASKNFLSDYYYHCADNGIPMVPILFNLAPCGSQKTLEFMKWLGISIPRWLE
NDLLHAQDILENSLRSSREVFEELFDFGVQKGIPIGCSVESVSTRKVEIEAAVQLAMEIK
AFMGVRLRGTIIERSGVRATRSS
>A0A6J1QKL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Temnothorax curvispinosus|TrEMBL
MRNLILEKDTCERSDADTNDSKDNPSVHGFDTGNLRKTVVDLRQSLRDKINKNEIFCSFE
IVSTRKPGAFYRRLLIDMEEYSPLFYSLTWHNEAASSNDSYLPLDLVENFPPNTLLHLAA
KGLKRDEVVRILKKTLALGIVNIFALRGDSLSENGDFEHAADLVAFIREQFGDTFCVCVA
GYPQTHPESSSKELDLHHLKAKVEAGADFIITQICFESRLLIDFVRDCREIGIRVPILPE
ILAPASHACLEKMTDICGLDVPVEIKDDLARMKDDDRAARKYSVDLITRIITDVIRSGVT
RGFHLSTLNR
>A0A6P8IX30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinia tenebrosa|TrEMBL
MGLGQQEPATPTIEIIQDLENQSKSSSPISVPSTPLSLIEKIKNKIAMDEKFFSLEFFPP
RTPNGAVNLLGKFDRAARGCPMFCDITWHPAGDPSGDKETSSMTVASAALNYCGLETMLH
MTCANTTKDDVTKHLQKAKGLGIRNILALRGDPPDGDEWKALDDGLAYGTDMVRHIRKEF
GDNFTICVAGYPAGHPDCNNYQEDIQHLKEKVDAGADFIITQLFFENKTFFKFVKDCREV
GITVPIIPGILPIQGYASLRHLVKLSRLEIPQSIIDALQPIKDDDEAIRKLGIQMALDMC
RELLDSGIVPGLHFYTLNREIATREILCALGLWCSDPAASRPLPWRASANQKRFTEDVRP
IFWASRPKSYLYRTSEWDEFPNGRWGNSSAPSFRDLSDHHFFYLRSRAKIDERLKMWGTK
LERVEDVYEAFSCYISGKENREGVKVKSLPWNDDELASETDIIKAKLEYLNSEGILTINS
QPAVNAKPSTDRLVGWGGEGGYVYQKAYLEFFTSPETVSILLEVLKDYPLVNYHVVNAEG
TVDITNCHQDTPVAVTWGVFPGKEIMQPTVVDPISFKIWKDEAFSLWEQQWGRLYPEESR
SRKVINEIINTFYLVNLVDNDFVKGTCLWHVLDKVVSIAKSKEDTKESHTSQPMQL
>A0A0M9CCA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp. NB4-1Y|TrEMBL
MTTTSAASSVVERLSAPPVNGPVHFSVEFFPPRDAEAEARLWRAVRVFERLDPAFVSLTY
GAGGSTRDRTVRIAGEMATETTLVTVAHLTAVDHSIAELRSLVGAYADKGITNLLALRGD
PPGDPLGEWVAHPQGVRYAQELVELIDGLGDFHVGVASFPEGHHRARDLDEDTAVLVNKL
RAGAEYSVTQMFFDVEDYLRLRDRVVAADPEQGAKPIIPGIMPITSLASVRRMAELSGSV
IPPAVEARFAAAAGNGPEEDRAAVRATGIDFATETAERLISEGVPCLHFCSLNFTKATCE
VLGRVGVDVRAAMVAPAVG
>A0A3N4KGB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morchella conica CCBAS932|TrEMBL
MVHIGKKLQEKHKDGKPTFSFEYFVPKTAQGVQNLYDRMDRMNALGPQFIDVTWNAGGRL
SNLTCEMVNVAQSVYGIETCMHLTCTGMPRSKVDNALKEAYKSGCTNILALRGDPPRENE
KWEADPHGFHYAKDLVKYIKQNYGDHFDIHVAGYPEGCEDQEDVDLLIQHLKEKVDAGAS
SIITQMFYDVDIFLDWVKKCRAVGITVPIIPGIMPIHTYAAFMRRATWTKCHIPEKWTEL
LEPVKSDDVAVRDIGRDLVVEMCRKIIDAGILHLHFYTMNLATATRMCLESLGLIPSLEE
RTKALPFRPSLGLRRDKENVRPIFWKNRHHSYVQRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLRGSNDSNIKIYGHPKTVRDVGKLIARYISGDLPSLPWSEGKINSEADSISKELVD
LNSRGFLTINSQPAVNGVKSTHPTYGWGPKNGYVYQKSYLELLVTPELLAELITRIERDS
NLSYHAVDKTGSLKTNSMEGPNAVTWGVFPGKEIIQPTVVETVSFLAWKDEAYRLGEDWA
HCYENNSVSRHLIQGIMDSWWLLNIVDNDFHESTRIYRLFDGLSVDGLDNTLDDELVEKL
AAATVAAVA
>A0A5N1M5J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
THSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGDLPPGSGKPE
MYAADLVGLLKEVADFDISVAAYPEVHPEAKSAKADLLNLKRKVDAGANRAITQFFFDVE
SYLRFRDRCVSAGIDVEI
>A0A087LWK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Devosia riboflavina|TrEMBL
MTADKRPELQISFEFFPPKTDAMEEKFWESINKLAPLKPRFVSVTYGAGGTTRERTLRMV
RHITSDTGVPAAAHLTCVGASKGEIDDVVRGFAEVGVKSIVALRGDPPEGIGQPFTPHPQ
GYQNAADLVAGIRKLGDFDISVAAYPEKHPQSADWDADIDNLKRKIDAGANRAITQMFFR
NADYLRFVERARKAGVTAPIVPGIQPIHSFKQISGFAARCGASIPDWLAERFDGLDADPD
THALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRPD
>A0A0R2USR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR86 cluster bacterium BACL1 MAG-120619-bin26|TrEMBL
MKISYEFYPPKDLNYQKIIEEYSLLSNFGPRFISITYGALGSSQEKSVGLIKAFKESVDV
EVVAHLTLVGKSKQELSFIVDEFSSMGVTKIVALRGDVAEGSFIAHQDGFQNTAEFVDFL
AKKKMEVFVSAYPEPHPDSKGFDFDVRLLKDKTLAGSRQSISQFCFSMHEYQRLVDAIKD
QNIQNDLTAGIMPIYNIASLCSMAERCGIKIPPEIIGQFSEDPQKNEQASIKICIQQLED
LQAMGINNFHFYTLNQSSLLKKIFNEIGF
>A0A402DS68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas biazotea|TrEMBL
MSAPTLGAASVPLSAPVPAEDPSTATADGTPSRRTTGPHVNGEVRPLAAVDRPTVSFELF
PPRNPDAAPRLWDTIQHLADAHPDFVSVTYGASGKTRQTTRALVRRLLRETSLNPIAHLT
CVGTSREEITTIVEEFLDEGARSFLALRGDPPVGQPDWQPHPDGLHTAGELVELLREIES
RRCAGSPSQAVRARVRPLSIAVAAFPRGNAATGGTRAQDVASLLAKQEAGADFAITQVFF
DAEAYLGLVAEARDAGVTIPIIPGIIPATDPARLLRVQDLTGVPVPRDLLDLLGAADDDL
DRHRRGIRAGVDLVQGVLDGGAPGVHLYTFNQHHAALDLLEGAGLDGGARDGRQAAPGSA
RPIPTAAPAPTATDPTHEGQTPR
>F0XLK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grosmannia clavigera (strain kw1407 / UAMH 11150)|TrEMBL
MDKITDKIAGLSPNASYFSLEFFPPKTAMGFANLRGRLDRMARALHPLFVNVTWGAGGST
VQKSLELAEICQRELGLTTCLHLTCTNMSCDLIDKALEDAKALGIRNILALRGDPPRPTE
YADSGKTSAAGEMADETGFSHAVDLVRYIRKQHGDYFCIGVAAYPEGHAEENHPLGQSLE
HDLPFLVEKVHAGADFLMTQLFFDIEAYEHFETTLHQHPSGVFADIPIIPGLMPIQNYQM
IKRTTKLSHARFPDGLMARLEDVKKDDEKVKSVGVDILSELVEQVKTIKHKTQPGRPTGL
HFYTLNLEKAVAFILERTNLIPSTRPATALEEVEVAVVDDALAVPSIRVHGAITMPAVHS
FERRHSSIGSDPRNRVIVPGPSASHPDYETTALEASVPAEPVNTRANTLAISEGEGVLGR
EATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSVGQAMKLWGRPSTADDVSQIFIRHLRG
ELSAIPWSEEEFNPETETIRDRLVSLNKKGWWTVASQPAVNGLESTDATFGWGPPNGFVF
QKTFVEFFLPSADWAKLRSRLQEPAVRDNICFYAATAAGELESSDADSTQNAGDGSGAVG
EASTHAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWKEWAGVYPKGSDSAKLLESIR
DDYRLVNIIHHNYIDRDALWKLLFD
>A0A4Y9SV33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella callida|TrEMBL
MDNPNFSIEFFPPKTAEGADKLRVTRAKLSELKPKYFSVTFGAGGTTQRGTLDTVLEIMA
AGEDAAPHLSCVGGTRESIRAILAEYKSHNIKRLVALRGDLPSGYGAAGEFRYANELVEF
IRQETGDWFHIEVAAYPEVHPQARSPRDDLLAFERKIKAGANAAITQYFYNADAYFQFVE
QAQKLGITAPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VTALGERLLKGGAPGLHFYSMNQAVATTALWERLAKV
>A0A3A5L6H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium waimense|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDAVVREFADMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKGAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSTRCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHEAEAA
GSAAA
>A0A5I9B8B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Eko|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8I0Z632|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSTERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALAAFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQLARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQPTPLPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAEAAQSK
VFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQSQVHTLEQWAPA
WQASWQMPGLPAVIFHPPQAAWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRRPLWATRVGAQVLHKVERAVKRPWVGCDTCGRCRLEDTLYVCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFQAATP
RRVSPQPAPRSQPES
>A0A8I1JQZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSVLKTALQAQQFACVMEFVPKPSAERFAAMDAIMARGQVCGWPMTLAIGDRVSSPLDMS
PLDALACFEHPLPALPHFSGKDRERHHLLAQMRRMDAAGQHQLLMLTGDRLPGHTPGERP
VRYLESVAALQIARQAYPHWWLGAALNPFKYHEEEGAAQYLKAEKKLAAGADFFILQLGF
DAAKHQEAMHWMRRQRAPKPMLVCLMSLTLGRAGMLDHVAGVTVTPSMRQMLEAEAAQSK
AFAQARSIDRLALQIIGVKLMGYAGVHLSGIHEPSQLLALEARLEHWQAHVTTLEQWAPA
WQASWQMPGLPAVTFHPPQAAWREGESRVVASFAQKARYHAMHGLHGLLFSRRNPMSQLF
GWAVRQPLWTTGLGAQVLHSLERAVKRPLLGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTTLNRCEFGDRECIHSAKYRTAKAVRQTDVLAQRLIPCVEQHTRHRSSWPGWFGAQAQ
PVTRPSAPRSRPES
>A0A220ME34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus formosus|TrEMBL
MTTRKKDLRAYLKDQLLVGDGAMATQLHGLGVPVGVSFEELCLSNPRLVHEVHTSYYQAG
ARFLETNTYSANRDALSRYGLEHKVARINRLAVAIAREAAQDDAYVAGSIGSILAGRVKK
KVLDEYRDQYEEQAIALLHAGVDGLILETFLDLEELLLAIEVIRPLTDVPVIAQLATLEV
GRTRDGYALTDAFSELKAAGADVIGLNCRLGPAELLRSFENTVIPEDALLSVFPNAGRLG
MTDGEYAFKSSPEYFGQSALRLREQGVRLIGGCCGTTPAHVKAIADALESLEPQARVNPT
IVAGDRPSISVQNTREREKPSIVERVKTATTIIVEFDPPRDLDADQFLHGCCELHKAGAD
AITLADNSLATVRMSNMALGALMKSRHGIDPLLHLACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGVSFSGRPLKQKAQFIVGAAFNPN
VRNMDAAVARLEKKVEAGADYIMTQPVYDAESIRNVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSTEALERMKKVQGEAARQEGIAIAKELVDTAVRYFNGIYLITPFNYYE
MAAELIQYTRQQSSLMRMAQT
>A0A532U3N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium B3_Chlor|TrEMBL
MKIQEFYARSPLTYSFEVFPPKTDRGVLKLYDTIAELKALDPSFISVTFAPDRTNRDRTF
QIAAHVKKKLGLESMFHFTCIGATEEQIIQDLDMARALDLENILALRGDRPEEAPSAPVR
NTFRYAYQLVLLIKDRYDFGMGVAGHPEGHIECQDKEQDLQHLKEKVDAGGEFVITQIFF
DNGYYYDFVERAQRIGISVPIIPGILPILNLTQVKRFAALAGATIPPNLARHLERLGDND
AAVRKLGIDYATQQCLGLLEQGVPGIHFYCLNRSASVKAIFKNLGPRWFSGNGNEEISKE
KVEVEMVKDQVYGVE
>K0YZR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winkia neuii BV029A5|TrEMBL
MTTAHLYKGYKPGQQVAHPTVSFELFPPRSASKLSSIWAGVDRLIAAAPDYVSVTYGASG
AKVDTRDTSVRVLTRVLDRHPGLPAVSHLTCVGATRGQLAMTIRLLLRAGIRDFLALRGD
PPAGQSEFEVVPGGLASAAELVALIREIAADTLPDGVGAGPNGAGADSAPNPKNYVSIAV
AAYPASSGEYRRNDIAALLEKELAGADYAITQVFYDPDEYASLVRELTIAGGRLPIVPGI
IPLTDLKRLNALEKIAGVTVPEEVSRTLQITDARERVAKSLRATLNLIDGVLAAGAPGVH
LYTFNRPRPALDVFEYVRASGYRNGRMPKRGEIDTELVDLALHRLTPSN
>A0A1M5FAP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium defluvii|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFTPKAGGNHYAIDLVKQINDLNCGKYLHEVMDADNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFAFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A149ZY76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. LB1|TrEMBL
MTRTPSIVDRIRSSSDGRVPFSVEFSPPRDEAAEARLWRAVREFERLGPAFVSMTYGAGG
STRDRTVRVTGQLAEETTLLPVAHLTAVSHSVDELRSMVGAYADRGISNILVLRGDPPGD
PLGEWEKHPDGVEYAEDLVRLVRDLGDFHVGVASFPEGHYRAPDLAHDTRFLVSKLRAGA
EYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSVRRVLELSGSRLPAH
LEKRLATAAGDGPEENRAAVREIGIDVATEMSERLIAEGAPGLHFITLNFARATSEVLAR
LGDKVGSGVADPAPVTPARVS
>A0A177SPL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MTQERRYSFEFFPTKTDAGHEKLLATARTLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKAELRALLAQYKAAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIREETADQFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNAESYFY
FVERVQKLGVKIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EEVITQMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>X6C9E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNJC372A00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A6B3LSH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontibacter burrus|TrEMBL
MKVTDHFRNANGKTLFTFEILPPLKGENMKTLFSHIDPLMEFNPPFIDVTYHREEYVYKQ
RENGLLEKRTTRKRPGTVGICAAIQNNYKVDTVPHLICGGFNKEETENALIDLHFLGIDN
VLVLRGDCVKSEQRFVPEPGGHNYATELIGQVVDMNCGRYLDDEQTFHNPTDFCIGVAGY
PEKHFEAPNHKSDLRWLKKKVELGAEYIVTQMFFDNQKYFDFVKRCREEGITVPIIPGLK
PMTTKSQLTLLPSLFHIEIPCELADAIEECSDNKAAAQVGVEWAIKQSKELMDFGVPCLH
YYSMGKSESVRKVAEALF
>K0N9S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula toluolica (strain DSM 7467 / Tol2)|TrEMBL
MKTESKLEKVLASGNLAVTSEVGPPRGAIPEIVREKANLIKDHVDAVNVTDNQTAMVRMS
SWAAGVIIKQMGLDPILQMVTRDRNRLAMQSDIIGAYSLGINTMMCLSGDHAKFGDHPMA
NGVFDLDSVQLVQTVKKMRDEGKFQGGADIKTPPKMFIGAAANPFADPFELRVMRLDKKV
RAGADFIQTQCIFNLDKFEKYMEMMCDRGLDEQVHLLAGITPMKSAGMAKYMKNKVPGMD
VPDEVIKRMEGVSKEEQPEEGIRIAVESIQRLKEVKGVHGFHIMAIEWEEKVPQIVEKAG
LFPRPVL
>I9TVZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus CL09T03C04|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKDGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVEAGADYVVTQMFYDNRKYVDFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAMKCKDDKEARALGIEWCINQCRELIAYGVPGIHF
YTVGAVDNVKEVATAVY
>A0A4U2CXQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. F13|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A1L5PX11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQVTADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>K0NLC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula toluolica (strain DSM 7467 / Tol2)|TrEMBL
MKSGSKLERILTAGHFAFTGELGPPRGSNIQVIKEKAAPLKGMVDMVNITDNQTAMVRMS
SWAGALILAAEGLEPNYQMVCRDRNRLAMQADILGAYALGLRNILCLSGDHQKFGDHPNA
KGVFDIDSIQLVAMVKKMRDEGKFLGGDDIDEPPKMFIGAAANPFAQPFEWRIHRLAKKV
AAGADFIQTQCVYNMERIREWIKMANDMGLTEKVYILPGVTPLKTLGMAKYMKNKVPGMD
VPDEIIKRLEGVDRKKVADEGIKIACEQIAEFKEMKGVAGVHLMAIEWEHKVPEIAERAK
VLPRPEV
>A0A1V5KCK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium ADurb.Bin490|TrEMBL
MKIADILRDKKFVFSMEIFPPKPDSDISVIYNTLDGLKDLKPDFISITFGAGGGTRTRTV
EIAERIENHYKIPCMAHLTCIGATKASITEILNELKAKNIQNIMALRGDLPEGVKNPLKD
FKYAADLVKFIKKKWDFCVGVAGYPEKHPQAKDMKRDLKHLKEKVKAGASFITTQLFLNN
DHYFNYVKMVREAGITVPVLPGIMTATKLSSIERMTKMCGVEIPERFKTATSTCAIDNPV
CDETVKYTVGQINHLIKNGVPGIHLYTMNRVEQNRHIYEESDISKMRQ
>A0A2C5W4S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A381LLA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas euroxanthea|TrEMBL
MIDPDTPSLASTITDAYSLEVSATDIAGLSAAAPAIMRGATIAIPYLPNQDDAARLAAAC
MLRKLGFAPMPHLSARRIGSRDALHAFVRRAVDEAGVERCLVIAGDPPSPIGPFPDSVSL
IDTGVFERCGIRTIAVAGHPEGHPGMPASERWDVLERKCRSIAERGMAPLIVTQFAFDAD
LVLTWLHALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACTAMLSKYGISLGKLLGT
AGPDRFVDRLATGLTGAHGEVSLHFFPFGGIAQTVAWVEQYRARNAPHRAD
>A0A510NWB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces cellulolyticus|TrEMBL
MEKITEKIAALPPDSNYFSLEFFPPKTQMGSVNLQARLERMAQALRPLFVTVTWGAGGTT
AAKSLELAEICQRQLQLTTCLHLTCTNMTRSLIDEALEQAKALGIRNILALRGDPPRSEE
YNMDGDDDSNKDFTWAIDLVRYIRKTYGDYFCIGVAAYPEGHPGESQTDIQDPEKDLPYL
VEKVQAGADFIMTQLTYDFEAYQKFEDRLRNHPSGAIKTIPIIPGLMPIHGYKILTRVTK
LSGAHIPPAIMSRIEQVRSDDERVKQVGVDIVSEIANQIKSLPNPGHRGYHFYTLNLEKS
VTLILERCDLIPPSSDDSAIEDGIAIEEVDANNKGLKTLVSRRRASSINSGPHNRVIVDK
LHVPTDQQSEHSSRKSITYETLASSAGVPALNPPPRSTQLQISEGIGSLGREATWDDFPN
GRWGDSRSPAFGEIDGYGPSLHVNATVAKQLWGFPVSKEDIGTLFRKHVSGELYIVPWSE
GGAAEDANLNAETQVIKPQLLQIIEKKNWWTLASQPAVNGVRSDHPIFGWGPPGEGFVFQ
KAFVEFFCPTSDYQNKVKPTLLKHGSEEFSWFAINAAGHLESSFLLSASSSPKSEDASSA
IAADEEPVEVRESTGMAVTWGAFRGREITTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRG
SATERFLNETKNDVWLLCVIGHRYGAGTEPGSEEEKAEMNTLWNVLAGDM
>A0A1K1P8S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter sp. UNCMF366Tsu5.1|TrEMBL
MAAISFEFFPPKTDEQREQLDAAVQRLKAHAPEYVSVTFGAGGSTLSYTDETVRRLRAEH
ALSVAPHLSCMGGTRAEIAALLDAYKASGCRRIVALRGDLPSGMATPGDFRYAAELVAFI
REHSGNHFHIEVAAYPETHPQAENALVDLRHFKAKVDAGANGAITQYFFNPDAYFRFIDD
VAKLGVNVPIVPGIMPIANFSQLRRFSEQCGAEIPRWIVKRMQAHGDDAAAVRELGADVV
AELCRRLLAGGAPGLHFYTINRARATVSVLERL
>A0A443TP79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter suis|TrEMBL
MFETLIQKLQEDKFLTLETTPQHEPSMHNIIEKIKKFKLQDRVDGFSCTDNPLAKLKYNA
LFASLKLQMEFKKPVIATMTMRDRNKIALQSDLMGANDFDVRAILALTGDPAKMSDQPHS
KGVFEANSIMLLKIIKSFNCGMDFAGRPFKIEPKEIFPFAVTNSYAKNFSSLEKKMHNKI
QNGALGIISQPVFDIENAKKLLESFNIAKEGVEGDKKKAQLIFGLFPVTKLRTALFLSAQ
VPGIHVPQFWIDALESAHSISEEEEYKVGMKLSQDLFKELNKLHPKIHLMTANRFDVADE
IIS
>A0A560J3N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirillum amazonense|TrEMBL
MTTANETAVNEIAVNETAATDRALGGGEPLVTVPRDLRVSFEFFPPKTEKMEQTLWQAIR
RLAPLSPAFVSVTYGAGGSTRERTHATVTAIQQQTGIPAAAHLTCVAATKEEIDTIARAY
WDAGIRHIVALRGDPPQAADGSGGLGGSGYQPHPGGYAYATDLVAGLKRVADFEISVACF
PETHPEAASAAADIDNLRRKVDAGATRAISQFFFDTDRFLRFRDTVAAAGIAIPIVPGIL
PITNFARAVELGAKCNCAVPAWMDELFGGLDAEPETRQLVAATVAVQQCLRLEREGVRDF
HFYTLNRADLTVAICHMLGVRAPKAA
>A0A0X3UZ67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL F-4489|TrEMBL
MALGTASTRTDRAHTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTAELRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWVRHPDGVGYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDADIRHFVD
KCRAGADFAITQMFFYPEDYFRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAARILAVKDDPAAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQRP
>A0A3G9A8W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. NJ-530|TrEMBL
MTFDPVRGRSSEGWATRTPSIVDRIASSTGSRIPFSVEFSPPRDADAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSTEELRAMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPEGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
YDTKYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVSAYDAEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGPDENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTPDTSVGTAQAV
>A0A4Q0QV46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium zhanjiangense|TrEMBL
MSGAMTDVTTPGQDIRQDGHLKRPAISFEFFPPKTEEMERNLWDAINRLAPLDPKFVSVT
YGAGGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRG
DPVGGIGTPYFSHPDGYQSSAELVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKA
KVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTTV
PDWFAAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLG
IRAKSAQKAA
>U5C401|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodonellum psychrophilum GCM71 = DSM 17998|TrEMBL
MKINEYIQQAKETLFSYEILPPLKGQSLKDLLEGIAPLMEFKPQFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFHVEAVPHLLCGGFTKEETENALIDLNFIGVQNV
LALRGDAPKNEGKFTPEPNGHEYTTDLVKQIIGMNNGKYLHEETETGFHTDFCVGVAGYP
EKHFEAPSMKFDLKHLKEKVDAGAEYIVTQMFFDNQKFFDFEKKAREAGITIPIIPGLKP
ITTLGQISMLPRTFFLDLPDDLMDELEKCKTNADVKQVGIEWAIQQSKELVANGTQVLHY
YTMSKADATYRIAKEVF
>A0A7K7PZD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acrocephalus arundinaceus|TrEMBL
MVNETQQTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6S6SN97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Aureispira sp|TrEMBL
MKVTDHFKAANGETLISFEILPPLKGGKIQSIFDTLDPLMEFNPPFIDVTYHREEFIYKK
RSSGYYEKVAMRKRPGTVGICAAIMHRYGVDAVPHLICGGFSIEETENALIDLQFLGIDN
VLVLRGDARKFEGKFIPEPNGHPYALDLVKQLVNMNEGIYLDNDITNPEPSDFCIAVAGY
PEKHFEAPNHQSDLHFLKQKIDAGAEYIVTQMFFDNQQYFDFVKRCRSEGINVPIVPGLK
PITKKYQLNSIPRMFHLDIPKDLSDGLLNAKDAKARLQVGIEWTVAQSKELKAAGVPCLH
YYTMGDVDTIKAIVAQIF
>A0A173HAI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. JY-Q|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQASPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALETRIEHWQSQVQSLEQWAPA
WHASWQMPGLPAVTFHPPQAGWRLDESRVDASFKEKARYHLMHGMHSLLFSRRNGLSKAF
GWAVRQPLWATRAGAHVLHTLERNVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A7Y6GIV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CAI-85|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFYAPKTPQGEKSLWNALRRVEAVAPDFVSV
TYGAGGSTRATTVRETQQIVVDTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSTAWDTDVEHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPRLSNAHF
PGELKERILTAKEDPATVRSMGIEFATEFCARLLAEGVPGLHFITLNSSTATLEIYENLG
LHHPPRV
>A0A8I1WMJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidaminococcaceae bacterium|TrEMBL
MKIINHLKGNKPGVSCELFPPKQGSQLDNALEIVRAIAAQRPSFISVTYGAGGSNAGEAV
AIAAEVKRCGVPSMAHLTCINADEERIENVLAQLRDKGVNNILALRGDLPDGVTLENATY
QHASDLVKKIKSFGDFCVGGACYPEGHPESAGLNDDIEKLKMKIDSGVEFLVTQMFFDND
TMYNYMYRLLAHGITVPVVPGVMPVTNAKQIQHICKLSDTKLPPRFRAIVEKFGDDPEAM
KQAGINYATTQVLDLLANGFMDVHIYTMNKPEIIGGILRNLSCIVKK
>A0A8B9CPW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anser brachyrhynchus|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
IELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPAQQE
>A0A1A0I7R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp. 852002-51296_SCH5728562-b|TrEMBL
MSQASPYTGPVNSSAPVPSVVERLSAPHPGQVPFSVEFLPPKDAEGEARLWRAVRVFERL
NPAFVSLTYGAGGSTRDRTVRIAGQLATETTLVPVAHLTAVDHSIAELRSLVGAYADKGI
TNILALRGDPPGDPLGEWVKHPEGVSYAEELVDLIGELGQFHVGVASFPEGHHRAPDLDH
DTRVLVSKLRAGAEYSVTQLFFDVEFYLRLRDRVAAADAEQGAKPIIPEIMPITSLASVR
RMVELSGSVLPESVERRLIDAAGSGEQEDRAAVRAVGIDIATEMSQRLIAEGVPGLHFIS
LNFAKATCEVLDRLGVDTSDALPLVSSN
>A0A0N8IGM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MSLQYSFEITPNIDQVNLDGLLKLNPEFISITDRNHDMDNLLQSIQIADYIHANSSVDVV
IHLTGIDKDEKRVQEMIDLMQQHDIHSVLALRGDKLSQKDTAVTFPHADRLIEFIKQQYP
HVNISGTCYLNSSDEEMKWLRQKIEKGCTNLISQFSFDANDYVDYLNQIEIDTPIWFGIM
PVISISQAEKMLNMTHSTAPDELNALMNHHGDEFGDDGVQYTAGMINKIKQSGASHIHLY
SLNNAENTEKMINKI
>A0A1R3FEJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 10N.261.45.E1|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A346AYX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera stantonii|TrEMBL
MRTNELFAKKTVFSFEVFPPKPDTPIETIYAALDELSQLYPDFISVTCGASGSGSGGNRT
VEVASAIKHTYGCETAAHMPCIYLTEDDALRTLDALKKAGIENILALRGDETPGRERAHV
FEHASDLVAFIKQNAPEFNVIGACYPEGHAEAQTMAADIRNLKTKVDAGASELISQLFFD
NATFYRFLERCEIAGISVPIEAGIMPVTNKKQIERMVSLCGATLPVKFQRAIAKYGDNAE
AMRDIGIAYAIDQIADLLANGVDGIHVYTMNNPYIAKKITEAVKNLL
>C5S058|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus minor NM305|TrEMBL
MSFAANIDQLNQNIADLNGKINVSFEFFPPKNEKMETLLWDSIHRLAPLKPKFVSVTYGA
NSGERDRTHSIVKSIQQETGIIAAPHLTGIDATPDELKVIAKDYWDNGIRNIVALRGDEP
PGYTKKPFYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGASRAIS
QFFFDIDSYLRFRDRCVNVGIDVEIVPGILPVTNFKQLQKMAQLTNVKIPNWMHKMYEGL
DNDPTTRNLVAASIAMDMVRVLSKEGVKDFHFYTLNRSELTYAICHTLGVRP
>N8NSJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP A162|TrEMBL
MSKQIPISFEFFPTKTDVGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGAPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAADLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A8I2J2J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. RM72|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPGADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASF
PPELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A8F7QH16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sanarellii|TrEMBL
MGFHSARQVEALNQSLADLGGDISVSFEFFPPNSEGMENTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLEHDQLTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKAQA
>R6K4I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:252|TrEMBL
MKDIRCYLKDNKLITDGAFGTYYAGLYDTRELPEKSNIDNKDRVIRVHKEYIDAGAKLIR
TNTFASNTINLDTDIDGVRSNIRAAVANAKEAVAQSGREVYIAADIGPIPNDNMFDKQVV
EDEYVQIVKAFGEEKTEVYVFETFSDLSNIIPAINAVPDGAFVIVQFAISQFGYSNSGLS
ARKLISAADGIERIDAVGFNCGIGPAHMEQFVERERKYTDKFFTALPNAGYPNIVSGRMV
FSDRNVEYYSQKVCDIIKAGADIAGGCCGTTPDYIRRISQLSESLDKLTVNSDKTYGEDE
KKSVTDSAFYSGKDGKKLIAVELAPPFDSNADKLMDAAHYLKEKGVDVLTFPDSPSGRTR
ADSILIAAKVSRQTGMCVMPHLCCRDKNAIAIRSQLLGAHINDINNFLVITGDPIPQMIR
SSVKSVFNFDSVGLMNIIDDMNEEQFTSEPVTYGGAINQGRKRLDIEIGRVKKKMAAGAT
FFMTQPVFSDEDIERIHTIKKETGARILCGIMPLVSLKNATFMKNEMAGIDVTDEVLSRY
RADMTKKEGEEAGIKLAVDVIEKTKDVADGYYFSFPFNRVYMLEDILRLSGLNA
>A0A7G1I1G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprobacter secundus subsp. similis|TrEMBL
MSIVDLISDKQSTAFSFEVLPPLKGNSIEKVFNTIDKLREFDPKYINITTHRSEFVYKDM
EGGLYKRISERTRPGTVAVAAAIQNKYQIPAVPHLICSGFTKSETEYALIDLNFLGIYDL
LILRGDKAKHDNKFVPTPDGHTHAIDLQQQVNRFNEGYFLDGSKMSLMDTPFSYGVAGYP
EKHDEAPNPESDLNYLKEKVKAGASYVVTQMFFDNDKYFAFVERCRAEGINVPIIPGIKP
IVLANQLTVLPKVFHVDLPEPLAKELQNCKNDDDAKQVGIEWCTMQAKELKSKGVPSIHF
YSMMATESVRRVAQAVY
>A0A7V9KLU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MRIPSILGGPEPCFSFEFFPPKTEEGTKALFESVADLHRLEPGFVSVTYGAAGSTRDGTV
EVTTRIQHEYGIEAMAHLSVVGETVEGIETILSRFADAGIENVLALRGDPPRGETDFQPA
PGGLRTSAELAAFVRAYEPTEHFGIGASCFPEIHPEADSAEADIAFLKEKVDAGAEFLVS
QLFFDNEVYFDWLAAVRDAGIEVPVIPGILPIISREGLHRFCKVCDARIPELLDEQLAAL
GGDEDAERAFGIAYASRQCEQLLAAGAPGIHFFVLNRAASVKAVLGALLAARPWERAPIG
AGREERRAG
>A0A848C2N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera hexanoica|TrEMBL
MKTCDLFSKKTVFSFEVFPPKKEIPVETVYPTLEKLSGLHPDFISVTCGAGGKGGNLTVE
VASKIKSLNCETAAHLPCINLDKDEVLDTLQKLREHRIENILALRGDKTPGIEPKCVFPH
ASDLIAFIRQQTGDEFNIIGACYPEGHPNSKTLAEDIDHLKIKVDAGASELITQLFFDNH
DFYNFLDKSTQAGIRVPIEAGIMPVTNKKQIERMVTLCGATLPLKFQKILTRYGHDNIAL
RDAGIAYAIDQIVDLLANGVDGIHIYTMNNPYVATRIANAIRTLL
>I0GSY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas ruminantium subsp. lactilytica (strain NBRC 103574 / TAM6421)|TrEMBL
MKRVSVELIPRDEETLRGELQLLKQYEGKIDVINIPDLLRFDTRSWEGSAIAQEYFAMSM
PHIRAMDIDLDKELPMKDYLREKGIKEVLVVQGDPPQRMTHEVYPTESTDVIRKFREEMP
EVKVYAGIDQYRSSMRHELYRTRRKVQAGAAGFFTQPFFDMRMLEMYMDMLDGLEVYWGV
SPVVTAASQSYWERKNNVVFPKKFQPTLEWSVDFSRQVMEMADKEDANVYLMPIRTDLEA
YLAGVLA
>A0A0J1JDC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium aphoticum|TrEMBL
MGYSYASHLDALNQNIADLDGNINVSFEFFPPSSEQMEQTLWQSIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKEQTGLVAAPHLTCIDATRDELRTIARDYWNNGIRDIVALRGD
LPPQGGKPDMYAADLVALLREEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNMKQAKRFALANNVKVPGWLEKQYE
GLDDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAEQSAPV
IG
>A0A2W7MHH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 478|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGANSAITQYFFNADSYFY
FVERVRAKGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A4U0WJM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Friedmanniomyces simplex|TrEMBL
MHITKKLAQAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGFGPAFIDVTWGAGGRMS
HLTCEMVKVAQSAYGLETCMHLTCTDMAQSKIDGALDEAYKAGCTNILALRGDPPREKEK
WEQSEGTAFRYARDLIKYIKDKYGNHFDIGVAGYPEGCDEETDADSHIPYLKEKVDAGGT
FIVTQMCYDAETFIDWVKKCRDAGIPESVSIIPGIMPIQTYDSFLRRAKWTQCKIPQDWL
KQLEPIKNDDAQVREVGKDLVADFCRKLLDSGTTMHLHFYTMNLAASTRMVLDELAVAPA
ADSHNPDLKPLPWRQSLGFNRRDENVRPIFWRNRKQSYVARTQDWDEFPNGRWGDSRSPA
FGGLDAYGIGLKGTNEHNRKLWGEPKTAQQIAELFVGYMSGKVESLPWSEAPISSEADIL
RQDLIDLNSRGLLTINSQPAVDGAKSSHATYGWGPKNGYVYQKAYLEVLIHPSILPKLIE
RMDEKEEITYYAVNHSGELKTNVTSDGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEF
YHLGLEWSKCYDEATESRRLIREIAESWYLVNIVDNDYRNNRGIFPLFDGLRVDGVDVKT
EPITNGDANGVAHVSGTANGEKEGKAPETNGVPDKNNTVNGADYKTAPMMTMKN
>A0A2H5DZH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium sp. (strain ATCC 53434 / SC 14030)|TrEMBL
MNPSPRTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGQAAAPHLSCIGSTRENIAAILNEYRGNGIRHLVALRGDIPSGMVAAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLANFVRKVRAGADSAMTQYFFNADSYFRF
VDEARARGVDIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRLRMQAYYDDTASIRALGL
DVVTELCDRLLQGGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A2U8GVW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azoarcus communis|TrEMBL
MNDTELSIEFFPPQTEEGAEKLRAVRARLAELRPSFFSVTYGAGGSTRERTFATVKEIAA
SGSEAAPHLSCIGSTRDSIRAILAEYAEAGIKRIVALRGDLPSGVGDAGEFRYANELVAF
IRAETGQRFRIEIAAYPEWHPQARSPKDDLLAFKRKAEAGADSAITQYFYNIDAYLHFVD
AVRGMGVDIPIIPGIMPIASFSKLARFSDACGTEIPRWMRKKFEAFGDDSESIRAFGLDV
VTAMCEKLIASGAPGLHFYSMNQSALTTEICQRLKLA
>A0A1P8XT30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces autolyticus|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRAELRNIIGQYAGAGIRNMLALR
GDPPGDPMGEWISHPDGLDYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIGHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATELCARLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>W9V7N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Imhoffiella purpurea|TrEMBL
MSTDTPIYSVELFPPKTAEGMEKLKREIPKINALNPAYFSVTYGAGGSTRDGTFETVDWL
RSQGIDTAPHLACIGSTKREVQEILERYRAQGIHRLVALRGDMPSGMGAGNSGDFRYANE
LVSYMRAEFGDTFLIEVAAYPEYHPQSGNPTRDLENFKRKVDAGADGAITQYFYNADAYF
GFLESCERAGIEIPIIPGIMPITNYSQLARFSDACGAEIPRWIRRRLEGYGDDAASIRAF
GHEVVANLCRRLIEGGAPGLHFYTMNQSGSVTRLWNELGLPGAAAAA
>A0A369IFE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Runella aurantiaca|TrEMBL
MTKITDYIQQANGKTLFSLEVIPPLKGSSIKELLANIEPLMDFKPPFIDVTYHREEYIEQ
ALPDGTVKHIVTRKRPGTLGICSSIMHKFGVDAVPHVLCGGFTREETEDFLMDLHYLGID
NVLVLRGDPAKPYKTFKPKTNGHEYASQLVEQVANMNKGQYLHEGVEALAPTDFCIGVAA
YPEKHFEAVDFDVDFEYLKQKIALGADYIVTQMFFDNSKYFEFVKRCREAGITVPIIPGL
KPLSTKKQLSVLPRIFYLHMPDDFVKAVEDCENDAQAKQVGIEWCTQQCKELMAFGVPVL
HFYTMGKSENIYKIASQLY
>A0A7I8L952|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirodela intermedia|TrEMBL
MKVIEKIRAAEQENGKTLFSFEYFPPKTAEGVENLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKSSGIQNVLALRGDPPHGQD
KFVQVSGGFGCALDLVQHIRAKYGDYFGITVAGYPEAHPDMIKGEQGVTAEDYQNDLVYL
KKKVDAGADIIITQLFYDTDIFLKFVNDCREIGISCPIVPGIMPINNYKGFLRMTGFCKT
KIPPEVTAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALGILMN
LGLIEESKISRSLPWRRPTNVFRVKEDVRPIFWANRPRSYIARTGGWEQYPRGRWGDSGN
PSYGALTDYQFMRPRSRDKKLQEEWGIPIKSIEDINERFSSYCLGKLSSSPWSELDSLQP
ETKIINEQLESINLKGFLTINSQPAVNGEKSDSSSVGWGGPGGYVYQKAYLEFFCSKEKL
DALVEKSKAASSLTYIAVNKDGQSVSNVGPAEVNAVTWGVFPAKEIIQPTVVDPASFAVW
KDEAFEIWTQVWASLFPDGDPSKQLLEQVQSSYFLVSLVDNDYVNGDLFAVFKNI
>A0A6B1FBE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. SB0676_bin_10|TrEMBL
MKSQVGPSAFQQALASGQPVITAEISPPRGGSVQHVLTTADRLRGRVHALNVTDGSRAVM
GMSSVAVCRLLLERNLEPVLQMGCRDRNRIALQADLLGAHALGLRNVLCLTGDPVKAGDQ
PGARPVFDYEAVRLLRDVKNLNQGLDALAQPLPDGPTALFPGCAADPQSPSWSGLKRRLQ
RKKEAGAQFIQTQMVTDLAALRRFCRELAAPLGLPVLAGVFLLKSGKNARFINRMVPGAS
IPDAAIARLDAARTPRAEGLRMAAEQVAAVLEIAQGVHLMAIKAESAIPQILDLAGVPPL
APPMVDSVGPRSLAVEPR
>A0A7X9W465|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp. Bel|TrEMBL
MSDSMSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGATRQDLRDILQAYKRDGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVAKVNAGADAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPLAVWKELAL
>A0A7X9ZAD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp. Bel|TrEMBL
MPLIHPSPLKSPSNITDAYSLEVSAKDIPALTAAAPRILPGSTISIPYLPGQDNDARLAA
ARAVRGLGFVPMPHLSARRIASLAELDVFVKRAVAEAGVDRCFVIAGDPSTPLGPFADSS
SLIETGVFERAGIQVVGVGGHPEGHPVMNPADRWEVLERKCHSISMRGMKPLIVTQFGFD
ADIVLAWLKTLRERGIEHPVRVGVPGPAGIAVLARYAALCGVSACASMWSKYGISLGKLF
GTAGPDVFVDRLAAGLTEEHGTVSLHFFPFGGIAQSVRWIEQYRSRAGQLRDASRALS
>A0A667WB73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myripristis murdjan|TrEMBL
TTFKCAVVLPETHHCHELSTMVNQVQRVDGNWQSGKSDSSGASNSGGESSKESSRCSTPV
LDADRSDRLRDKMLRRMESGDRWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWH
PAGDPGSDKETSSMMIASTAVNYCGLETILHLTCCNQTKEKITGYLAKAKHLGLKNIMAL
RGDPVGADWEEEEGGFNYATDLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKE
KVDAGADFIITQLFFRAETFLKFVRDCRKIGIMCPILPGIFPIQGYQSLRQLVKLSKLEV
PEEITRVIEPIKDNDAAIRNYGIEQAVEMCRLLLESGEVPGLHFYTLNREVATIEVLRQL
GMWIEDPRRPLPWAMSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPA
FGELNDYYLFYLKSKSSKDALLKMWGEELTSEDSVFEVFTCYITAQPNHSGHKVMCLPWN
DEPLAPETNLLKDELEKVNRRGVLTINSQPNINGKPSSDPLVGWGPAGGYVFQKAYLEFF
TSSENVNALLKVLKKYEPRVNYHIVNVQGHNLTNAPEMQPNAVTWGIFPGREIVQPTVVD
PVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVI
DDMFELLDMPPELVTDGAVSE
>A0A6G8KY35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium luteolum|TrEMBL
MSTISASAPLDAWSPAAAPEAGVAAGTSGTRLALSFEVMPPRSAAQQERSGALLELLASY
DPDYVAVTSAVGTGWSAGTAAFIEQLAATTRLRPLAHLTCTAAPREELTEWIERFIDAGV
RGFLAVRGDLAAGQSAPPRGHLAHADALVALLRAVERGQVARLCAGRLAIGVAAYPNGHP
ESRHPEEDIDVLAAKQRNGADFAITQLFFDPALITAVAERARLAGVTLPIIPGIMPITGT
ARLQRMCRLSGLTPPPRISQALAAARSPAEEYDIGLDLTAGFVDELIAAGVPGLHFYTFN
DPTTITELLSRLRPATLARLIADRKDFP
>A0A846X4D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tsukamurella spumae|TrEMBL
MLRGVTEQSRTVLDRLDAVRASGRMPFSVEFMPPRDAEGEARLWRAVRTFERMDPAFVSM
TYGAGGSTRDRTVRVTGEIAETTTLLPVAHLTAVNHSISELRALMGAYADRDVRNVLVLR
GDPPGDPLGRWVRHPQGLKYASEVVELVRELGDFHVGVAAFPEGHHRSPDQDSDVRYFAN
KLRAGADYSITQMFFDVDDYLRLRDAVTDFDPEQGVKPLIPGIMPITSLKSVSRMAELSN
AKIPEAMRAELRAAAGDGPEENRAAVRAAGIEIATRMGERLIAEGAPALHFCTLNFAKAT
SEVLENLSMLPVGV
>A0A444T503|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armadillidium vulgare|TrEMBL
MVKEMEEAVPNSTEDTLSILKGFIESRSRDSISESSSADSCLDCHIPKPDLIWGFPNLKE
KIVSRIESGDKFFSLEFFPPRTKGGAVNLLARFDRMRAGDPLFCDVTWHPAGNPGGDTET
SSMTIASAALNYCGLETMLHMTCCALTKTEIRNHLKRAKDIGIRNILALRGDLPCDVEDW
TPPEDGFRYSTDLVKFIRQEFGNYFVICVAGYPNGHPEAESYEEDIKHLKEKVDAGADFI
ITQLFFKAETFINFVKDCRKAGIEVPIIPGVMPIQSYDSLRNIVKLSKLDIPEEITDQVA
PLKDNDEAIRNYGVDQCCKLLRKIFNSGYAPGVHFYTLNREVATTTILKQLGLWSCSPKR
PFPWKMAANHKRCSEEVRPIFWASRPKAYVYRTQHWDEFPNGRWGSSESPAFGELKDYYL
FYLKSKSSKDELLAMWGETLESEQDVWKIFACYLTGQPNPSGNKVTMVPWNDNELSPETS
YLKEKLAYFNTKGILTINSQPNVNGASSEDEVVGWGMPGGYVYQKAYLEFFTCKENVEAL
KKVLPLFPRVNYHIINKDVRIRYI
>A0A074SVJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani 123E|TrEMBL
MKLTEKLATYRSDTPYFTFEFFPPRTDQGYSNLLTRISGLASLKPVATSVTWGAGGSTRD
RSLDLAGFCQADNDLDTILHLTCTNMEKGTIDEALMTAMERGVSTVLALRGDPPRGEEYW
IPTDPRFQHAEDLVTYIKQHPTFASHFCVGVAGYPDGHSEGGSEEEQLTHLKRKVDAGAE
FIITQLFYDVEKFKSWLRKVRSTGITVPVIPGVMPLQTYATFTRMTDLCKATVPLHIQAN
LDAIKHDDQLVKEYGVSLAVSMIRSILVDGDVKGVHFCTLNLEKSVRKILDELGWTHESL
HHNQIIIDANQSPHILPSPADAPHPTTFTISPSEAAQHANTSLAEHTRTGTLRTAAEAID
SGWDDFPNGRFGDSKSPAFGLIDPWDGGGLGVPPHVAIAQWGRPTTEQELSDLFLAYLND
TTSTTPFSPEPLSDESATILPHLVSLTKKGLWTVASQPAVDGALSSDPVIGWGPRDGRVF
QKSFVEFFATEADLEKVAQAIEDSGDGWLTFFAGNNEDGFLTNIPDSGSNAVTWGVFPGK
EIAQPTIIDRDSFLAWKDDAFMIWHDFGLCYPPDSPTRKLLEDVINTRWLVNIIHHDYKN
SNALWDFLAKYLE
>A0A842LIA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Archaeoglobi archaeon|TrEMBL
MKVFSNLMREIKEGKFVFTGELEPEKETNLESTVKAAQELKGYVTACNVTDNPNSMAYVS
SLVASYIIQERAGMEAIYQLRCTDRNAAALTSDILGACVLGIRNILALTGDHIALGDYAK
AKPVYDLDSAQLTYMIRRMVDERVDLYGNEIHGEVKLHVGVAANPNCEPLEAEILKLGRK
VEAGAEFVQTQVIYDIERVGEFFELMREHGIRVPVLIGIFPLKSYGVAKFFDEHVAGVHV
PAELMEKITKAKDEPDKQKRKEKILEINLEFFIPFLKELKKTEAAGCHIMAVGYPEIIPP
LTEAVR
>A0A6A5QTY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ampelomyces quisqualis|TrEMBL
MERITDKIDALPDGANYFSLEFFPPKTAMGFANLTTRLERMSRALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMDRALIDEALEQAKVLGIRNILALRGDAPRSEE
YRDEGQTPEQDSNKDFTWAVDLVKYIRKEYGDYFCIGVAAYPEGHSDESHPEHQDPSHDL
PWLVEKTKAGADFLMTQLFFDVEAYDKFETMLREHESGAFRTIPIIPGLMPIQSYKILLR
TTKLSHAKIPASMLARLDAVKSDDELVKQVGVEILDEMVEHIKSKPGIGKRGFHFYTLNL
EKAVSHILEDCNLIPREDLEDENAIIVETTPAINLEPPTNGLLARERRRLSSAHSGPRNR
VIISHPSATKSNHSYEATEEEAGIPRSPINTRANTLAISEGEGSLGREATWDDFPNGRWG
DARSPAFGEIDGYGPTLHVSTTQALKLWGHPVDTGDISNLFRRHIQGELEALPWSEQGLS
PETSTIAKQLLALNAKGWWTVASQPSVNGVRSSDPVFGWGPKNGYVFQKPFVEFFLPAAQ
FHQLKERLDAHEQVTYFAGNAQGDFEASSEESVNPVTWGTFAGKEIVTPTIIEAVSFKSW
LEEAFSIWRVWQRIYPTKSASGKLLGQTRQDVWLVNVIWGDYVEGSGLWEFLGA
>A0A6P0EJJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas euvesicatoria|TrEMBL
MISTDTPNFASTVTEAYSLEVSAKDIGALTNAAPRILPGCAMFIPYLPGQNQAVRLAAAQ
MVRSLGFEPVPHLSARRIGSLGELQACIARLVDEAGVTRCLVIAGDPSTPKGPFPDSVSL
IETGVFERSGIRTIAVAGHPEGHPILRTTEQWEVLERKCRSIQERGMAPLIVTQFGFDAD
IVVTWLEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLF
>A0A0U1RII7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)|TrEMBL
MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEP
PGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
>A0A1C0ZZ84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus pectinilyticus|TrEMBL
MLKDKILRKEPGIITYGMTPPKETHTQDKIKEIAHKQCERLQALQIDGLILYDVQEESDR
MEQDRPFPYMKTVDPTTYSNEYLTTLNIPKIIYRCVGKYTEDQMAEWIKADQEQERFSVF
VGASSSKQAVQMDLTEAYDLSRKLNENLTLGSVVIPERHMKKDDEHLRMVSKIKCGSRFF
ISQATYNVEASKNFLSDYYYHCKENHLEMVPILMNIAPCGSTKTLEFMKWLGISIPKWLE
NDLKYSSDVLDKSVAVTQQIFEEIFEFGLEKGIPIGCSVESVSTRKVEIDASIQLVHDIK
AMIEKKLRPSFVF
>A0A0A7K8I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulophaga baltica 18|TrEMBL
MKVTDHIKNANGNTLFSFEIVPPVKGNSIQELYANIEPLMEFNPPFIDVTTSREEYVYVD
KAGLYDKKITRMRPGTVGICASIKHKFDVDTIPHVICGGFTKAETEYMLIDCHYLGIDNV
MALRGDAMKEEKYFKPTEDGNCFASELVTQIQNLNQGRYLHDDVQGEDKSDFCIGVAGYP
EKHLEAPSFKSDLIRLKQKVDAGADYVVTQMFFDNQKYFQFVEAAREIGINVPIIPGIKP
IAVKRHLQLLPQIFSLDLPHDLVEAVEACKNNAAVRQVGVEWAIQQSKELKAAGIPVLHY
YSMGKSNNIKAIAKEVF
>A0A2V1HGW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. S1B|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRAVHQDLQQLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFKIEVAAYPEMHPQAESFDQDIQRFAEKVHAGANSAITQFFFNPDAYFYFI
ERIAKLGVHIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSKSIQEFGHE
VVVKLCERLIAGGAPSLHFYTMNHIQPNRQLVTDLGLA
>A0A2D7P076|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halieaceae bacterium|TrEMBL
MSAAKSLLKSLYFEVIPMKGFEEKLGVLKAGDRVGITCSPKQGLQVTLDTVAQLSDRGFS
LTPHLAARQVMNKQHLKDIVAQLTDSGITSIFVPGGDLDEPMGEYDSSAAVLRDLSEMDH
PFTRIGVASYPEGHPAISDDLLFEALAAKQGIATHMVTQMCFDMPVLIKWLSDMRDRGIT
TPVWIGLPGVMDRMRLFKTSLRIGVGQSAKYAKKQKGLIGMFLRSPTYKPDSLFKELQPA
MADERMAIEGLYMFTFNQIDNTVQWSQEQLKRLG
>A0A1G0NSJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium GWA2_54_16|TrEMBL
MTLREKIESNQFVVCGEVAPPQSCDGDVIREKARHFKGYVDAVNITDNQTAVVRMSSIAS
AKILLDEGIEPIMQMTCRDRNRLAIQSDLLGAAALGIRNVLCLTGDHQKFGDQPEARGVF
DLDSIQLLATVAAMNKGLLLSGTEMKKASAFLIGAAANPFAAPFEMRLIRLQKKVQAGAH
FIQTQPVFDLEIFARWMGRVVDMGLHEKTAILAGVLPVKSVKTLLWMREKVPGVRIRDEY
VRRMTETRDPEEEGVKMAVEIIQTLRTIKGVRGIHLMPALWESITPTIIKEARLSAEELE
KESH
>A0A238WVW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. DSM 44272|TrEMBL
MSTEGRDVATARDGRASARSPDDRPAPRRPREVLRGALRGASYEVLPLRTAEEAVVGHVP
RDVPLTITTTEAKGLTPTIGLAERLSGHGFDATPHLAARLVRDESHLTDIVARLRAAGVN
GVFVIGGDAAEPAGTFPDAFSLLEKLETIGHHFRHVGIGGYPEGHGHISAELIERALERK
APHATHIITQLCFHPSTTTAWARQVQLRGVDLPIRIGLPGAVTRQKLVRISAGLGLGQSA
RFLAKQQSMFWRFFLPHGYRPDRLVERLAPALASPENKLQGFPLFTFNEVARTEAWRQEW
LARLSYAVTD
>A0A1F0NQ91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC066E07|TrEMBL
MSSPSPSLSFEVFPPNPAVGNEKIMVALKEMQDLVPHFISVTASNNKFNIEETTVRLADF
IHNDLHIPTIAHLPAVYLTKEMVTETLTALDKVGVHKVLALRGDIFPNMEPKKDFTYATD
LIEYIKEQAPHFEIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYD
FQDKCILAGIEVPIHAGIMPILNRNQVLRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSDTAHRIYQATHTFFDK
>A0A1H3SA73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbiconiux ginsengi|TrEMBL
MVVTTEQRLACPKHMEYGPCGGVEFDGSCEVGDFRCVFLETPTVRWHGIAPNPLSPTGVA
NAAIEGAGAATGHAVVAAGHASVDVHHLADAHEFPVAPQRGAAAMRALLAARPIVVADFP
GRSVDRASLTDCAQALAGRVDATLAGDSGRSRVQFSPSYRAQLVQNEGLAVWTGLNCRDR
NRVALEGELAGLADVGVAGVHCVTGDHTATGNRHDALPVFDLDSTQLTALARQAGHLVSV
AEAPLTPPVDRRAARLHEKVLAGADVCFVNHSGGVEPVRRFIAESHGLGIAPAFIPCVPM
VIDAGSASLLKSFTTLVLPEGFLDGILHAAHPYDAALDAITRLCEEFLAVDGVAGVNLSG
GPAAGAEVAFADAMGVVAERLGLG
>A0A2V9Z7Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MATDLISRLKKSPVLCDGAMGTLLYGKGIFINRCYDELNLSQPDLIRSIHHEYLQAGAEI
IETNTFGANSFRLARHSLADRVHDINLEGARVARDAAKSFDVWVAGSIGPLGVRIEPLGK
VALDEAREAFRHQIAALVEGGIDLVILETFGYVEELHQALLAARDVNPNMPVVAQVTIDE
DGICLDGSTPETFAPRLVDWGADLIGCNCSVGPVAMLDAIERVRAVTSHPLAAQPNAGMP
RSVEGRNIYLCSPEYMASYARKFVAAGVRLVGGCCGTTPDHIRVMKSALRVGEARSPKVQ
VAKPQPTPAATTAVPLRERSRIGFKLATGEFLTMVEIVPPKGTDIRKEVEGARFLKSVGV
DAINIPDSPRASARMSNQALSLLVQRDVGIEAILHYTCRDRNVLGIQSDLLGAAAMGIRN
LICITGDPPKMGNYPDATAVFDVDAIGLVNIVHNLNRGLDIGGNPLGTGTSFVIGVGANP
GVPNIDEEIRRFEYKVQAGAEYAVTQPVFDLSLLENFLRRIEHCRVPVVAGIWPLVSVRN
AEFMKNELRVSVPDSILQRMSRAATPEAAREEGVAIAREMLIAVREMVQGAQISAPMARY
ASAVDVLEALGTRGAPA
>A0A3R7I8J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanophagales archaeon|TrEMBL
MGDEVYSDLMRELKEGEYVFTGELEPEKAGNVNEPIRMAKELKGLVVACNVTDNPQSFAY
VNSMAASYKIQEEAGMECVYQLRCADRNRMALLSDVLGAGTLGLKNILALAGDHVSLGDT
PDAKPVFDLDSTTLIKMIRTVVDEGKDLGGNEIEDPPKLHVGGAAAPGAAHLKAEVAKVR
RKIKAGVEYLQTQVVYYTDVLDKFFDELGNVDTPVLVGIFPARTFGQADFFDKFVAGVDV
PPDYLEAMRKTKEIKDKEKRKEEVDRVNVEFFTGFLEHLKGTPAAGCHMMAVGYPRIIPE
LKKIME
>A0A2V9HMM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIYDFNERLKDSILIADGAMGSMLHEAVGFERCFDELNSTEPEAVFRIHQAYIEAGAQI
IETNTFGANRFKLAPLGLAEEVQRFNSRGVKIAREARESAAREVLIAGSIGPLGLGVQSR
HPSPEEIQEIFHEQALALEERGVDFYILETFSYIEELLLAIDAIRLFSGLPIVAQLTYAE
EGTTYGDVRPSDAAAQLKNKNVQVIGANCTLGPQALLPILEELAAVDGLRVSGMPNAGFP
KREGDRIVYPRSSPEYFALFAREAAALGVRILGGCCGTTPAHIRAMAEAVKLLRPSKTHP
VVRSVETVLRPVPVARREPQSRFWKQLQKKEFSVCLEIDPPKGLSLDRIFEQVDKVMASK
KVDAIDINSGAMARVGMDALIVAGALEARGIETVPHLTTRDQNIIGLQAALLGAWTVGGV
RNVLAITGDPPSVGDYPETSGVYEVDSVGLVKVLNRLNQGTDWAGKTLGGATNFTIGVAV
NPVADDLDNEIERFHAKVEGGAHFAMTQP
>A0A2V2R8Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MNFRDLLESDSIHVFDGAMGTMLYAKGVYINRCYDELNLSNPDLVREIHSEYIRAGADII
ETNTFGATAHKLQQYGLENSLRDINIAAAKIARECAGDSVYVAGAIGPLGLRIEPYGPTS
FDEAKDLFKAQAAALLDGGVDLFIIETFSDLSEIRQAIRAVRELCDLPIIAQMTIMTDGN
TLFGTTPELFTERLDQWGADVVGLNCGVGPAIILAALEKMRAVTKKKLSAQPNAGLPRDV
QGRQFYMCSPEYMSKFAKRFIQSGAKFIGGCCGTTSAHIKLISDAVRAASPRAQRAVFST
GPLGRVEEITPTDIKVVPPDERSEWGRKIAHGEFVTSVEVLPPKGVDSKKTLDSIRLLKE
AGVDGVNIPDGARAQSRMSAMATAVLVEQQIGIESVLHYCCRDRNLLGMMSDLLGAAALG
LRNLLLITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGEPTAFCIGVG
VNPGAINLDEEIKRFEWKVEAGAQYAITQPVFDTEQLADFIRRIEHVRIPIIAGIWPLVS
YRNAEFLHNEVPGVRVTPSIMERMRVASTVSKEAGREEGLKIARESLLEVRDLIQGVQVS
APFGNVKYALEVFDVLEGFGKARELEIEGKPS
>A0A7W0FZZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
LRIEPYGPTSFDEAREMFKEQVTALLEGGVDLFVLETFSDISEIRQAINAVRELCDLPVV
AQMTIQMDGNTIFGTTPEVFTARLDEWGADVIGLNCGVGPAILLPAVEKMRGVTRRKLSA
QPNAGLPRDVQGRQFYMCSPEYMAKYAKRLINAGVKFIGGCCGTTPAHIKLISNAVRAVS
PRRRDTSPLGIVVPVSVEELKPSDIKVVPPEERSNWSRRLVRGEFVTTVEVLPPKGCDAT
KTLEQIRLLKDAGVNAVNIPDGPRAQTRMSAQATAVLVEREIGLETVLHYCCRDRNLLGM
VSDLLGAAALGLRNLLLITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPV
GCPTSFCIGVGVNPGAINLEEEIKRFEYKVEAGAEFAITQPVFDVEQLRAFLKRIEHVRI
PVVAGIWPLVSYRNAEFLHNEVPGVRVTPSIMERMRAASERGKEFGRDEGLKIARESLLE
VRELIQGVQVSAPFNNVRYALEVFEALPEFGAQAVANTTSVDG
>A0A2V8INW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MQDLLTRLGNHVLVCDGAMGTMLYSKGVFISRCFDELNISNPELVREVHLDYIKAGADII
ETNTFGANRTKLMTHGLADQIRHINIQGARIAGDIAGDNILVAGAIGPLGIRIEPWGKTA
IEEAQVTFREQAKALVDGGVHALILETFFDLNEVYAAIRGVRDVTDQPLIVQMSIEEDGN
SLEGTPPEVFAKRLEEWGADVLGLNCSVGPQVMLDAIERIANVTSKKLSVQPNAGKPRNV
EGRNIYLGSPEYMASYAKKFVQYGVRIVGGCCGTTPQHIKAIRAAVKSLGVAVLGHSPGA
SRRPLPAGEGTEGESSIPLESRSRLGRKLATKEFIKIVEMIPPIGHDFAKAIEKAKYLQA
QDVDAINVPDAPPSSARMSAISLAVLLEKSTEIESLAHYTCRDKNLLGMQSDLLGAYALG
LRNLLLITGDPHQIGEHSDATAIYEVDSIGLANMVSRLNGGVDVGGKSIGKPTGFVIGVG
ANPGAMSDLELKRFFYKVEAGAEFVLTQPVFDATVLERFLDRAGNSKIPVIAAIVPLPNY
KAAEFLNYEIPGCSIPDGILERMRAAQSKSPEHARNEGILIAQEILERIHGTVQGVQIRG
PFDRYETPVEVLSVMMKGATR
>A0A8F6H5X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcus capsulatus|TrEMBL
MKTQLKYPREFSFEFFPPKTEEATENLRRTLTKLAPLKPRFCSVTFGAGGSTREKTFETA
LEIQQTTGIECAPHLSCIASTRRSIREILEAYRSHGIRHIVALRGDMPSGMLSAGEFRHA
NELVEFIRSETGNHFHIEVACYPEVHPQAASAESDLKNFKRKVDAGADSAITQYFYNPEA
YFRFVDDCERLGIDIPIVPGIMPITNHSQLVRFSDLCGADIPRWIRKRLEAFGDDRKAIR
AFGLEVVTELCRRLLEQGAPGLHFYTLNRAEACLEVWKALGLEPA
>A0A2S8X5V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. MYb63|TrEMBL
MKADLRKVMQERVLVGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQISALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GEFRYGATPEYFGQTAVQFAELGARIIGGCCGTTPDHITAMKEALADYIPSPILEPDPSE
SKPRIVLHEHVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLEKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFIGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A842XK78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanophagales archaeon|TrEMBL
MPGEVYSQLMKELAEGKYVFTGELEPEKAGDVKEPIEAAKELVGLVTACNVTDNPQSFAY
VNSLAASYKIEKETGMECVYQLRCSDRNRMALLSDVLGAGVLGIKNILALAGDHVSLGDT
PDAKPVFDLDSTTLIYMIRKMVDEGKDLGGNDIHNPPKLHVGGAAAPGAAHLKAEVAKVK
RKIKVGVEYLQTQVVYYPEILDKFFKELGKVDVPILVGIFPAKSFGAADFFDKYVAGVDV
PPDYLKSLEATKEIKDKEKKKQEIDRINVEYFTGFLEYLKGTPAAGCHMMAVGYPRIIAP
LKKVME
>A0A7X8AKH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPADNFLRFLQKEHLAFMDGAMGTYLFQQGVPMDSCIEALNLSQPALVLGVHREYMAAGA
EMLMTNTFGAGAVRLQRFGLDDRLEEINAAGVRLAREAAGRQGYVAGSLGPLGALIEPLG
KLGVDEVEAFYQRQVRCLVEAGVDLLILETMSQPAEAAAAVRAVRHLTDLPLLVSFAVGD
NGLTRYQTPLERCLAELPLDQVDGVGLNCIVGPYAMLNLVERARTLVDRPFLVMPNAGRP
RQLDGRTFYVSTPDDFRRAAPRFLDLGVTLLGGCCGTTPDHIRALCESVRAERARRKWTQ
VVRNRGDAGSVGTAAEPPAAPQKAEGRAPSRLSQQLAAGRRVSLAELVPGKGAGSGKAQG
RARALQEMGVDAINIPDGPRATARMSPLALSVLIQQQVGVEAILHYACRDRNILGIQADL
LGAWALGIRNLLLITGDPPVVGDLPRATGVFDLDAIGLVNLVHSLNEGRDVGGNALDEAT
DFFIGVGANPFADPLDRELARLRWKVLAGADFIITQPVFDVEPFLAFMAHAAEFGLPVLA
GVWPLVSLRNAEFISSEIPGIHVPRRILEELGRYPDPADQQKAGLAMTADIVRRLMAVAE
VRGVQFSIPLGRYQVLGDLVAEVRQ
>A0A7Y3E4A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MQTFRQALNDSRFALSAELTVKRNSSADYVRRQADRLGGLVDGIQVTDNPYAWVQMSALS
AAAILLDHGFDPVPILSCRDRNRLALQSDLLGLEALGVSSLILMRGHRVPQDHAVPAATV
FDLTGRELIALASSLESQPLIGTGARVFRPGPRWQAESLLARAAAGAGFTQTQLCFNMDI
LRRYMKRFVAAGLAERFAVMVSLSPLPSAAAALWVKNNMSDSRIPDALVARLEDAGDPER
EGIRICAELMQEVSQVPGVAGINLMTTGNSETIPEAIRISGLRAA
>A0A2V9FJV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIYDFNERLKDAILIADGAMGSMLHEAVGFERCFDELNSTEPEAVFRIHQAYIEAGAQI
IETNTFGANRFKLAPLGLAEEVQRFNSRGVKIAREARESAAREVLIAGSIGPLGLGVQSR
HPSPEEIQEIFHEQALALEERGVDFYILETFSYIEELLLAIDAIRSFSGLPIVAQLTYAE
EGTTYGDVRPADAAAQLKNKNVQVIGANCTLGPQALLPILEELAAVDGLRVSGMPNAGFP
KREGDRIVYPRSSPEYFALFAREAAALGVRILGGCCGTTPAHIRAMAEAVKLLRPSETHP
VVRSVETVLRPVPVARREPQSRFWKQLQKKEFSVCLEIDPPKGLSLERIFEQVDKVMASK
KVDAIDINSGAMARVGMDALIVAGALEARGIETVPHLTTRDQNIIGLQAALLGAWTVGGV
RNVLAITGDPPSVGYYPETSGVYEVDSVGLVKVLNRLNQGTDWAGKTLGG
>A0A7Y3AZH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MAAKPNISFEFFPPRTETQQRVLDATWRELAPLDPSYLSVTFGAGGSTLESTRETVLDLA
AQTAVPVAPHISCMAQSEEMLRTLLADYHEKGIDRLVVLRGDRPEGVGNTGPFDHANELV
AFIRREFGSAFHIEVACYPEFHPESESPASELLFFKQKVEAGADGAVTQYFYNVDSYFSF
VDDARRSGIDIPITPGVMPITNYRQLARFSQMCGAEIPQWIRRRLKGFGEDTEAIHAFGL
EVVTRLCERLLEGGAPGLHIYTLNRAQASKELWQRLNPV
>A0A7Y2FEK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MKTFRQALHGKQFAISAELSLGRASTHQDIARQASIFRGRVDGVQIADNPLAWVHMSAVS
ASALVLREGLDPVPILTCRDRNRIALLSDLLGLRAMGVSSLLLMRGRRVPARHALHASTV
FDLTGRELIAMAAGIGEDEDAPSPFFIGTGVKAHRARKGWRAEALNQKAELGAQFIQTQI
CYNLDLMKHYLQRLVEARATWDFSVIASLAPLPSSETARWVKENMPDSKIPKRLVQRIEQ
AADPEQEAVLACAETMQAMSEIPGLSGIHLMTTGDAELIGAAIDTSGLARTEGAGQQEAQ
A
>A0A7W1DD11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
VQVVPAEERSNWSRKIARGEFVTSVEVLPPKGCDAAKTLQAISSLKVAGVDAVNIPDGPR
AQTRMSAQATAILVEQNLGIEAVLHYCCRDRNLLGMMSDLLGAAALDLHNLLIITGDPPK
MGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGQPTAFSIGVGVNPGAINLEEEIR
RFEWKVEAGAEYAITQPVYDTEQLREFMEKIAHVKIPIVAGIFPLVSIRNAEFMHNEVPG
VRVTPEILERMRKASDISKEHAREEGLQIARESLTEVRDLINGVQVSAPFGNVKYALQVF
DVLDELSAKNAEVSQQL
>A0A1I2B8Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. OV194|TrEMBL
MGLLKDLEDKILIADGAMGTLLYSYGTDCCFEQLNLTHPDQIQSIHQAYIQAGADVIQTN
TYSANYIKLQRYGLEEQVKELNSAAVRLAKKAAANEAYVLGTIGGIRGTGPSSLTIEEIK
RSFREQLYCLLLEGVDGLLLETFYDLEELETVLEIARSQTSIPIISQISLQEVGILNDRT
PINTAIRRLEDLGADVVGLNCRLGPFHMIKTLEEVEIPKHAYLSSYPNASLPSYVDGKFQ
YEGDAEYFKNSASLFRNQGIRLLGGCCGTTPAHIEAFAEELHGLKPVTEKEVRQRPEPIA
VVETRQKPGISLPEILKERRSVIVELDPPRKLDTSRFFEGAKALKEAGADAITLADNSLA
SPRICNTSLSSLAKARTGVQPIVHLACRDRNIIGLQSHLMGLHTLGLHDILAITGDPAKV
GDFPGASSVYDVTSIELIKMIKQFNEGVSLSGKDLGQKTQFTVGAAFNPNVKSLERAVQR
AEKKIESGADYFISQPVYSEEKLLEFHEAVKDLPVPFYVGIMPLTSSRNADFLHYEVPGI
KLTDDVRDRMAKFKDDPVSAAREGLAISKSLIDAASELFNGLYLITPFMRYELTAELTEY
AYEIDRKKTRRIQNV
>A0A554VNI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimarina algiphila|TrEMBL
MKVTDHIKKAEGKTLFSFELIPPQKGRSIQELYNNIDPLMEFNPPFIDVTTSREEFIYID
REGLLDKKLTRMRPGTVGICASITHKYDVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFTPTKGGHGYANELVTQIVNMNKGQFLHEVIETDNKSDFCIGVAGYP
EKHMEAPSMDSDIRRLKEKVDAGADYVVTQMFFDNKRYFSFVEKARAAGIDVPIIPGIKP
AAVKRHLQLLPQVFKLDMPDELVRAIEGCKNNAAVREVGVEFAIQQSKELMEYGVPVLHY
YSMGKSDNIKKIASEIF
>W1J3W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus szentirmaii DSM 16338|TrEMBL
MSFFHANQREALNQNLAELDGQIHVSFEFFPPSTAEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERNRTHSIIKGIKEKTGLDAAPHLTCIDASRETLRNIAHDYWHSGIRHIVALRGD
LPNHCGKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATMTNVRIPSWMTRMFE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPV
>A0A1Z8TU59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium TMED51|TrEMBL
MHSVASDPGQALPILEGHVSAGRLERVLRSGKFAVTAEIAPPDAADAGAVYQRASVFDGC
VDAINATDGSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVTN
ILCLTGDGVQAGDQPDAKPVFDFDCISLLQTVTAMRDQGEFLSGRKLTTPPRVFLGAAAN
PFGPPLDYRPIRLEKKINAGAQFVQTQYCFDLVRLREYMSRVRDMGLTERCYILTGVGPM
PSARTAAWIRDNVPGVHIPDAVIKRLLGAENQKEEGVRICVEMIQAVREIEGVHGVHIMA
YKQEERVRDIVEESGVLEGRIPWYPGVSNDQQGQQN
>A0A1H3JW35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citreimonas salinaria|TrEMBL
MPRPEISFEFFPPKNIEGTFRLWDTVNVLAPLAPRFVSVTYGAGGTTRDLTRDVVATLTK
HSGLRTAAHLTCVEATKDETLEIARGFKAAGVRDIVALRGDPPKGASGFTQHPDGFANSV
ELIEALAAEGDFDIKVGAYPDKHPEAADAQADIDWLKRKLDAGASEAITQFFFETETFLR
FRDACVKAGIDKPIVPGIFPVENWKGARRFAEGCGTKIPAWVCDAFDKAGRDGRSDLLAT
ALCTEMCSDLIDEGVDKLHFYTLNRPELTRDVCHAIGATPEARLEKVA
>A0A345RXD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas kribbensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A1I6Y0U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus locisalis|TrEMBL
MKITEHLGNAKNTLFSFEILPPLKGQSLKELLEGIAPLMDFKPPFVDVTYHREEFIYKKH
PNGLLERISTKKRPGTVGICAAIMNRFHIDAVPHLLCGGFTKEETENALIDLNFIGVENV
LALRGDAPKTEGKFIKEPEGHGYASELIEQIIRMNQGRYLHEETEIGFQTDFCVGAAGYP
EKHFEAPSMKFDLKYLKEKVDKGAEYIVTQMFFDNQKYFEFVDQVRSAGINVPIIPGIKP
ITTLGQITMLPRTFFLDLPDPLMDELEKCKTNAEVKEVGIEWSIQQCKELVNAKVPSLHF
YTMSKADTTYKIAKEIF
>A0A1C5SR44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Blautia sp|TrEMBL
MKMKELFDRGEFAVSAEVGPPKGIHVNELVEEAKTYLTGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMFGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPELLKLAEI
>A0A2E4JDW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTLSVNLPTRLVRDFYSGRQSSDRPVISFELFTPKTGEGDRKLIEHTLXELIGLKPDYVS
VTYGAGGSTRTKTLTLVDLIQRRYGLTAMAHLTCVGHTKSDIAGILEEAKSLGIRNILAL
RGDPPVGQETFSKPEGGFEYSYQLIQFIRSSGNFCIGTAGFPEGHIACRQGKVVDWGYLK
NKVESGADFILTQLFFDNADFFRFRDHMVQKLGVTVPICPGVLPILSAKQIARFTKLCGA
RIPDRLQARLELLASDDDGAREFGIEQATEQCEELMREGVPGLHLYCLNRAQSVSGILRN
LGLSGV
>A0A4Y7QAR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickenella mellea|TrEMBL
MKITQKIEQATKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQSLIGIETCMHLTCTNMPKEKVDIALREAKQHGCRNILALRGDPPMGQDE
WEAVEGGFVHGIDLVRHIRKNYGDYFDIAVAGFPQTMLLPPAERDLEMQYLKEKIDVGCN
FIFTQMFYDVELFIDWVKAIRAAGITIPIVPGIAPIQTWNGFQRATSLAKTIIPQTFLDA
LEPHKNNDEKVREIGTKLVADMCRRIIKEDVGIRGLHFYTMNLEKGTKMLLEELEFVARV
ETIKPLPWRQSLTPNRRSENIRPIFWANRTKSYIARTENWDEYPNGRFGDSRSPAFGELD
GYGVWIKQTKEEGLNIWGRPTTFGEIASLFARFCLSDLPALPWSDQRPSAETTVIGKQLA
QINKLGFLTINSQPAVNGARSDDKIFGWGPVNGYVYQKAYMEFFVTPQLLEVLLPYIERD
NNITYYAINKRGDLRTNNHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAFELGQQ
WSEFYDHDSPSRKLIADLMETCFLVNVVHNDFKDSEAIFRPFLKAGAEYMARNSTEKLNG
MSLVNGAVNGINGVNGAH
>A0A640YB99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRIPDLIAASEEPCFSFEFFPPKTEEGVAELFASVEDLNRLEPSFVSVTYGAGGSTREGT
VEITTRIKREYGIETMAHLSVVGETIAGLDAILGRLDAAGIENVLALRGDPPRGEPDFTP
PPGGLTSSAELAAFIRGREATARFGIGASCFPEIHPEAASPEADIAFLREKVEAGAEFLI
SQLFFDNAVYFDWVEQVRDAGIEVPVIPGVLPIISRAGLHRFCDVCKAKIPARLDERLAA
LDGDPEAERAFGIAYASRQCEQLLAAGAPGIHFFVLNRATSVKAILGAIKAGRPWERTGG
EVAAAARGRR
>A0A523ESC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MLATAGPWVEMIELNPPRLPDTSHRELEGKWTDVLITDNVFGQVRVSPYAYAARITHDIP
AVRPTVVVSTRDRNILAIESEVRGAIGNGVRSMFVVVGDTLPEVDHRANHYEIVQHLRRL
QDDLPTFEVGMPTRLQEWTFRKRIDAGAQFFIAGPMLDPATIEPSVARLNLRDDDPPVFL
GIVPPFSPRWAKRMVGVGAVEGSDEFRARLSAVPKEKRRPHAWLLAREAADRARDAGCRG
VVLMGLKFETVVGEAYTEWNNEV
>A0A2E6NJQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRLIRDIYADRQSVDRPVISIEFFTPKTSKGDQVLCESTLPALIRLRPDYCSVTYGAGGS
TKSKTLSVTDMIQRQFGLTAMAHLTCVESSKNDIGAVLDEAKELGIRNILALRGDPPGGS
GEFVKADDGFEYSYELVRFIKANGDFCVGTAGFPEGHXACTEGKHVDWGYLKNKVDCGAD
FVLTQLFFDNSDFLRFRDYIVRKLGVTVPICPGVLPILSTKQISKFTQLCGARIPKALAA
RLESLRDDDEATTAFGIEYATKQCEKLIREGVVGLHMYSLNKAHSTSAIIKNLGLS
>A0A409WIP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psilocybe cyanescens|TrEMBL
MKITQKIEQSTKNDKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPKEKVDIALRDAKQSGCRNVLALRGDPPMGKEE
WEAVDDGFVHGIDLVKHIRREYGDYFDIAVAGFPEHMSLSQEECDREISYLKQKIDAGVS
FIFTQMFYDVDLFINWVKAIRAAGITIPIVPGIAPIQTWNGFQRATNLAKITIPKLFLDA
LEPVKNNDEKVREIGTRLVADMCRKILDADIGVRGLHFYTMNLEKGTKMLLEELNLVPRI
ETIKPLPWRQSLTPNRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGNPITFADISALFTKFCTSELKALPWSDQEASIETSVISKQLG
QINELGFLTINSQPAVNGARSDDKVFGWGPSNGYVYQKAYLEFFVNPTLLSLLLTQIERD
SNITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELGSQ
WAKLYEHESPSNKLISEFMETSFLVNVVHNDFHDPDAIFRPFYKAGAEYLSLKSNSTAVN
GH
>A0A3D6AK20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacteraceae bacterium|TrEMBL
MTNPTSVQHNFSIEFFPPRTPEGVEKLRAVRAQLAALKPAYFSVTFGAGGSTQSGTRDTV
LDIRKEGYEAAPHLSCIGRSRDELRTILKEYQEHGVRRLVALRGDLPSGYGAVGQDAGEF
HYASELIEFIRAETGDWFHIETAAYPEMHPQAKSPQDDLQNFIRKVQAGANSAITQYFYN
ADAYFRFVDDVRAAGVDVPVVAGIMPITNYTQLTRFSDMCGAEIPRWIRLKLASYGDDTE
SIRAFGLDVVTRMCERLLTGGAPGLHFYTLNQAGATTAIWQRLAR
>A0A3M2GVN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIGKYLREGKFSLSFEFFPPKTQEGEIELFETIKSLQPLSPTFVSVTYGAGGSTRERTR
RVVEKIHRETKLTVMAHLTCIAHTKEELLDILQDYKRIGIENILALRGDIPLDTEPPHGA
CKHAVEMVRLIRENFADHFSIGVASYPEGHPESPNMEWEFKFFKLKVDAGADFSITQMFF
DNRYYYEFLELCQRAGINVPIIPGIMPITNFRQIQKFAQMCGATIPQNLIAKLEPYEEKP
EELLKVSVDFAIEQCLDLLENRVPGLHFYTLNRSKATLMVYEGIRSALVA
>A0A532TRR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon Loki_b31|TrEMBL
MAKRKAYSQLCKAIEAGHFVFTGELEPKKILDLSEIIHSAKEMKKTKRIVAANVTDGPQG
DAYMASLVPSYKIQEEAGIEAVWQVTVRDRNRVALFGDVVAGAVLGLKNILTLTGDHTAL
GDHKKARAVYDIDSTQFCEMLSIMIDEGTDYEGNELKGGKIEMNFGCVANPNSNPREPEI
LKVGRKVDRGVDFIQTQTAFDIDDAKDFLKDLEQYNVPVLLGLFPLKSHGIAWYFDNYIP
GVSVPKDLLKALKKAEKDNKGNKPGKYAAIDKINIDFFKPFIAEIKKSTKAAGIHCMAVE
YERLFAPLLGDYPEYVKYSM
>A0A7W7RIQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lipingzhangella halophila|TrEMBL
MPSLAELLTDPAPARPVITAECPMVDGGGLDTISEHVRRLAPYVDALNATDNAAAHAHAS
NVGVAIALKRFGVEPIMQVACRDKNRLALEADIVGAALHDVTTICCMTGDDITAGDEPEA
LRVFDMDSPQLIRTASTLARGRYLSGRTLDPAPPLLIGAVENPGAPPYSYRVRRGLKKAA
AGARFLQLQICYNEDRLAEFTKLAENVGLSRKVALLPTICLVKGAKALRFMNEKVPGISV
PEPVIERVANASDEREAAYQLALEQARDALSLPGVRGLHFTDFRHDDALGRIVADLGLPT
IRSAPDGEALAV
>A0A8E2VFA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mammaliicoccus sciuri|TrEMBL
MSLKEALKNQILVADGAIGTILYSEGLDTCPESYNLTHPNKIEQIHRSYIEAGADIIQTN
TYGANFEKLQDFNLEHRVKEIHREAVQIAKRASNNHTFILGTVGGFRNIKKSNLSIEAIQ
YHTEIQIETLVNEGVDGILFETYYDLEELLAVLKDTKARYDIPIIAQLTASNTNYLRNGT
PIPDALETLVKAGADVVGLNCHHGPYHMIKTFKHIDLPDHAYLSCYPNASLLDLEDNDLK
YNNNSDYFSDAAKELVNQGVRLIGGCCGTTPEHIKKIKNVVKDLKPIKHKNVIPIETKQY
KKQNKEEPSIKELVQQRPTVIVELDTPKHLDTNKFFDGIQALEDAGVDAVTLADNSLASV
RISNIAAASIIKQKYKIRPLVHLACRDRNLIGLQSHLMGLSLLGINDILTITGDPSKVGN
FPGATSVFDVNSSGLAEIITQFNQGINADGDTLRSNTNFSVAGAFNPNVRRLEPAVKRLE
KKIESGMEYFITQPIYEPERVKEIYEATKHIDAPIFIGIMPITNYNNALFLHNEVPGIKL
SDTVLNAFEKVKDDRDATRELSINLSKQLIDAVHQYFNGLYLVTPFLKYDLTVELANYSQ
LKTGTQTKEAIL
>A0A849H604|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Knoellia sp. DB2414S|TrEMBL
MALGQSSRLARPESLTRSIPGMLSRPQPSISFEFFPPKDDAGEQVLWDAIRRLESVRPDF
VSVTYGAGGTSQDRTVRVTERIARETTLTPLAHLTAVGASVAALRQVIGMYAASGVRNVL
ALRGDPPGDPGGEWTPHPEGLNHATDLVSLVRSLGDFTIGVAAFPDVHPASPDLDHDVEI
LVKKADAGATFAITQMVFDADTYLRLRDRVAERRPLPITPGLMPVTNFKQVARMSQLMGT
PLPRAVVERLERVAGDPAATREVGVQIATELAERMLSEGAPGLHFITMNRSTATLEVHRN
LSL
>A0A850NMW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda chongwuensis|TrEMBL
MKITDHIKKANGETLFSFEIVPPVKGKSIQELYNNIDPLMEFKPPFIDVTTSREEYIYKE
KDGLLDKKLTRTRPGTLGICASLKHKYDVDTVPHVLCGGFTKEETEYLLVDCQYLEIENV
MALRGDARKEEKYFAPTKGGHQYATELVKQIQDINQGNYLHDTIKSSDLSTFCIGVAGYP
EKHMEAPSLQTDLKRLKQKVDLGADYVVTQMFFDNQKFFAFVEAAREMGIEVPIIPGIKP
IAVKRHLQLLPHVFSIDLPEDLINAVEACKDNKEVRQVGVEWAIQQSKELREAGVPVLHY
YSMGKSDNVKAIAKELF
>A0A6N1VCQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oricola thermophila|TrEMBL
MNAVSIETGGAPEKIAASIEISPKQAIESPDLPGLFPAGIRVYITDIGSDTNDTLVAAAR
RVHDLGYKPVPHFASRRLTTKAALEERVKAMTEDAGVRDILVVGGGLEQPAGEFSSTMEV
LETGFFDKYGITDIGVAGHPEGSPDFSEEVALEALRLKKSFGERTGARIRIVTQFGFDAE
KFIAWAESLRDHGIDLPVHLGVAGPARITTLIKYAAMCGVGNSLDFFKKRTRSLATLATT
HSPESIVGPIERHLLATPGSAIKQIHVFPFGGIKKSAEWLEERGTWDIKTSLYPSMESRS
>A0A6S6XQZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denitratisoma oestradiolicum|TrEMBL
MTKQISFEFFPPQTLEGMEKLRKTWEALENLNPTYFSVTFGAGGSTRDRTLETVLQIQRA
GLSAAPHLSCIGATRESLRSMLKDYKGAGVSRIVALRGDLPSGFVAPGEFRHASELVQFI
RHETGDFFHLAVAGYPEVHPESRSNRDDIEKFVRKVEAGADSVITQYFYNVDAYIQFVDQ
VRSRGVHIPVIPGIMPIANFEKIVRFSDACGAELPRWMRKRFDDFENDAESAKEYGLDLV
SDLCRRLLESGAPGLHFYTLNQSPLVAEICHRIGVA
>A0A7K5KW55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vireo altiloquus|TrEMBL
MVNETQHTCSVSSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPTGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCQELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGHKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6M0IQQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma agri|TrEMBL
MFLEKIKSGESGVLLYGITPPKAGTTPERVAEIAQKTIERLAALDIDALVVYDVQDESAR
TTEERPFPFLNALDPLVFASGYLDTLTIPKIIYRPAGKFSSIELADWLETLHAHQFYPVF
VGVPAPDFPVKTSLQEAYAIWSKHRDTSVIGAVTIPERHNVLNDEDVRILDKMNCGVSYF
ISQCVFNLDYAKQVIDDLSSRCNRQQISPPTIIFTLTACGSAKTLHFMEWLGIHVPDELK
DELKKSDDILEKSVNVCLDIASALTTFCVERSIPFGFNIESVAIRKAEIEASIYLANEIG
QMLKDKGVRKSLTGGTSEATNDLPNNIRYVS
>A0A7G9FP68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium NSJ-4|TrEMBL
MIQEKEHKGVVFSCEVFPPKRDDDIYQIYKTLDEIKTLKPDFISVTYGAGGSNSKKTATI
AAYIQNICEVEALAHMTAVGMDEASLRALLFELKKKGVENILALRGDKPRTMSQEEFDQR
YFKYATDLIPEIKKNGDFFIAGACYPEVHPESKNQEEDIQHLKQKVDLGLNCLITQMFFD
NNAFYSFMDKLEKAGIDIPVHAGIMPVTAAKQLGTSVTLSGSSVPVEMSNMIAKYGENPE
DMKKAGIEYAVNQILDLKKHGVAGVHIYSMNKADVTKQIYEASF
>A0A845AC77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Altericroceibacterium indicum|TrEMBL
MSYAAIHPDWEKPASNMVDGYSLEMTAKEMDHLREAAPLIRPGTPIAVTFLPGEEMEDRI
AAAKLVRELGFEPMPHLSARRLESTEVLENLLSRVTSEAGVKRVFMIAGDPPQAEGPYED
SLQIIESGLLEKYGIEAAGIGGHPEGHPNVSKDDLWVWMERKIAALRARNITPLIVTQFA
FDDEAILGWIKEMRDRGIDTPVRIGVPGPAGIKRLIGFAKRCGVGASANVMKKYGVSLTN
LIGKAGPDKLVESLERGLTPEHGRVRLHFYPFGSLKASAEWINDYDAKHS
>A0A7V5H244|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldithrix abyssi|TrEMBL
MKVIEHLTKAKDTLISFEIIPPKRGGDIHSLLQVVDDIAKFNPPFIDITSHAAEVTYEET
PQGIKRKVKRKRPGTLGICALIQNKYNVDAVPHVLCNGFTREETEDFLIDLQYLGIENVL
ALRGEENSYQKPLLNGRSANQYAVDLVRQISNMNKGIYLEEELIDARPSNFCIGVAAYPE
KHISAPNLDFDIKQLKKKIEAGADYVVTQMFYD
>A0A1Q7IGL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon 13_1_40CM_4_53_4|TrEMBL
MKLSERAKYHTIVTAEVIPDRVVPAHLPLLDGRVDAITIPALRNGENDPSYPSEFRVTPQ
TRSVASAVIVKKTGFEAVPSLTCRDFRRSDLPLLPVLFKKGLENFLVVFGDPYPNYEIKT
YDFKRAEDLIRGIRSVFDGQRPCIGAVTNQYALDREKEISRTLSKVDAGADYLVTNSAFD
DYYVLDYIDALRSSGLKVPIFVQLSIPHGLNNLLFVSRRFGIPVPESVKETVSRDPLGGG
VQVIARAFAGLRNEVSGIHFSYLFRSHNPIPTYTHLLDAIETDWQLVGSLQATLRT
>A0A8J2TRW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquaticitalea lipolytica|TrEMBL
MKVTEHIKKANGNTQFSFEILPPLKGQHIQSVFDSIDPLMEFKPPFIDVTYHREEYIYKE
LDNGLLKKQVVKKRPGTVGICAAIQNKYNVDAIPHILCGGFTKEDTENFLIDLDFLGINN
VMALRGDAVKTETYFKPEKEGHVYANELVAQIQELNKGNYLDEELQNSSKTNFCVGVAAY
PEKHMEAPSLDSDIHFLKKKIKNGAEYIVTQMFFDNKKYFDFVAKCRKEGITVPIIPGLK
PIATKKQLNLIPHRFHVDLPEELIIEVVKCKDNDQVRQVGIDWCIAQSKELQKAGIPVLH
YYSMGKSDNIKTIASKVF
>A0A3M6P229|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aggregatibacter aphrophilus|TrEMBL
MSYAKEIDNLNQHLANLNGKINVSFEFFPPKNEKMENLLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSVVKNIKQQTGLEAAPHLTGIDATPDELREIAKDYWDSGIRRIVALRGDEP
PGYSKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMASVTNVSIPAWMAKMYEGL
DDDQTTRNLVAASIAIDMVRVLSREGVKDFHFYTLNRSELTYAICHILGIRPTL
>A0A2N0ARY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira levettii|TrEMBL
MNQILLEVVPRDVSIVLQEVGFVKNNFHQITGINIPDLLRFENRSWDVASVVRPVFPNVI
PHIRAIDFDLDNCESLVKTLQQLQIASVVVIKGDPPTDMSKQVYPTTSVKLIKKLKKEIQ
HLKVYAAIDQYRVGIKDEFDYIEMKKDAGADGFLTQPFFDMRLVDIFSEKLKGTEVYIGV
SPVVTEKSQSYWESRNRAYFPKEFRPSLEWNVKFAKDVLTYCSANGMNAYLMPIRINLEE
YLRRIFD
>A0A109RNG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutibacter profundi|TrEMBL
MKVTEHIEQANGKTLFSFEIVPPQKGQNIQELYNNIDPLMEFNPPFIDVTTSREEHIYIQ
KGDLLDRKITRMRPGTVGICASLKYKYNVDAIPHVLCGGFTKEETEYVLVDCHYLGLDNV
MALRGDAMKHEQYFKATKGGHQYASELVKQINNLNKGKYLHEIIETPYNSNFCIGVAGYP
EKHLESPSLETDLRRLKEKVDAGADYVVTQMFFDNKKYFDFVKKARNIGITVPIIPGIKP
VAIKRHLQILPQVFKLDLPEILIREIEKCKDNKEVRQVGVEWAIQQSKELVAAGVPVVHF
YSMGKSDNIKEIASKVF
>A0A376DQ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Edwardsiella hoshinae|TrEMBL
MSFFHASQHDALNQSLAELQGRIQVSFEFFPPRTAEMEQTLWQSIDRLSTLKPAFISVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCVDASREALRTIARDYWQSGIRHIVALRGD
LAAGAGRPEMYASDLVALLRDVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIEAEIVPGILPVSNFGQLQRFAALTNVRVPQWMRAMFD
GLDDDAETRKLVGANIAMDMVKLLCREGVKDFHFYTLNRAELSYAICHTLGVRPQA
>A0A6A7C071|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piedraia hortae CBS 480.64|TrEMBL
MHITQKLAASHADGHPTYSFEYFPPKTPQGVQNLYARMGRMNSLGPAFIDITWGAGGSGS
SLTCEMVKVAQSEYGLETCMHLTCTDMGIEMITDALQKAYEAGCTNILALRGDPPKEKDS
WEQTDSTAFRYARDLIKFIKSKYDDYFDIGVAGYPEGCDDGTTADAHIPYLKEKIDAGGT
FIVTQMCYDAERFITWARKVRESGIPDHVPIIPGIMPIQNFDSFLRRAKWTNARIPPEWL
EKLEPIKGDDAAVREAGKDLIAGFCRKLLNSGVTKHLHFYTMNLAASTQMVLEELAVTPT
HGSPTESEPKPKYVVCSGTQQDTQTIDGGKITSNNVETVPAPAVSSVTAGTGGP
>A0A1F9L5K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYD12_FULL_56_24|TrEMBL
MLAEKTSPFRQSLRNPGQFTITLELVPSRGGHSREHDRTLELAEKLARDPRIQAVSITEN
AGGHAALSPEVLGREIQEMGLDVIVHFSSKDKNRNQMESLLFAWDRLGIRDLLVITGDYP
QEGYQGCAKPVFDLGSVHVLDLISKMNKGNYGSNRDAIRPTSFLMGVALSPFKRLEAELL
MQYAKLHRKAEHGADYIITQVGYDTRKFHELLQYVRHNDLNLPVLGNVFVPNLTVAALMH
TGKIPGCIITDELYTEIRREAAGPDKGKQARLLRGAKLLAILKGLGYAGAHLGGPGLSYD
NIDFLLTTADSLAENWRELAAEMGYWHQDGFYLYKKDEKTGLNTSEPAPLAQGWAGLQLN
YRLARLVHNLAFTQEAPLYPAGKKICLALEGGKLDNSLTHLEHVTKFLLFGCQNCGDCTL
ADLAFVCPQAGCAKYLLNGPCGGSRDGWCEVYPGKKRCLFVRVYERLAACGLPESMRQGF
VPPRNWALNNTSSWLNFFRGLDHAGGKKHFPSI
>A0A7S7QX87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. CCBAU 51753|TrEMBL
MTETVSPVSNGHRAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGSTRE
RTHSTITRILRETDLLPAAHLTCVGSSRGEIDEIVDRYHEVGVRHIVALRGDPPAGIGTP
YFTHPDGYQSSAELVAGIKKRHPDIEISVSAYPEKHPEAASFDTDIDTLKAKVDAGANRA
ITQVFFDNDLYYRYVDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAEKFD
GLDNDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPHGAQKA
A
>A2S6W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia mallei (strain NCTC 10229)|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>X6HNR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L2C067A000|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDEIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A2A4AIV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium accolens|TrEMBL
MTPRLSASAPLDQINEWTARVRQRTALSFEVIPPRNDADASKISELLAVLQSYHPDYIAV
TSSQRSGWLRGTAAFIEQIARTTSMRPLAHLACTAGSPGELSEWVDVLVDSGVRGFLALR
GDLPEDGMPAGYLQHADELIRLIRRREAAQAARFAAGHLAVGVACYPNGHAESANADEDI
DVLLAKQRLGANFAITQLFFDPEDYARFYQRARLAGVRIPLIPGIMPMTSVARLERMAGL
SGLDVPPKVRAALAAAKTPEEEQEIGMELTAELARGVLRAGAEGLHIYTHNNPAITQDLL
SRIGVNR
>A0A1H1LG34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolymorpha singaporensis|TrEMBL
MPAPAFEVVCEVEPPARPDLAHVRRQIEVLGPVADAFLAPDNHLGRATISSVAVAHEIQR
AGGRGLACLNARDRNLLGLRRDLLTAAAYGVERFVFVYGDKPTSGNRTGDLTVRAMLEEV
RRFAEEPELRGGGFRAGVAAGPGPLPAWKRAADFVFTQVGFDVTGQVRWRETHGPDCPVY
AGVLVLSSEAMARRLAASIPDLNVPEELIRRVGQDRRAGVEAACEQVERIRDSGAFDGVH
LVTGVRFGPMAEELTRRGLARPAQSGPGLGPAAR
>A0A177K979|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium oleivorans|TrEMBL
MSIIQPPSVTTVPVSFEVYPPRSDASYAALYETIDRLAAVDPAFISVTYGAGGSGGGRSL
EVLTHILRETRVEPLAHLTCIGSSYAEATALIREFLDAGIRSFLALRGDPPAGAGEDAAA
LGDLESAAQLVQLIDRVQAETSPYTEEPIPGVPGAARVERRPSVDIAVAAFPNGHPRSRY
PAEHIDALLAKQAAGATLAITQLFFHADDYLAFVARARSAGVEIPILPGIMPITSPSRLR
RVIELTGEQVPGSLAVDLDVEPTADGRREIGVGHAADLCRAVLAGGAPGIHLYAFNNHDT
VLATLREAGIIPATEETS
>K1L1U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cecembia lonarensis LW9|TrEMBL
MKITEYIAQAEKTLFSFEILPPLKGQSMQDLCDGIAPLMEFKPPFVDVTYHREEFIYKKH
PNGLLERVATKKRPGTVGICAAIMNRFHVDAVPHLLCGGFTKEETENALIDLNFIGVQNI
LALRGDAPKSENKFIPEPGGHTYTKDLVKQIVGMNHGKYLHEETETSFHTDFCVGVGGYP
EKHFEAPSLRTDLKYLKEKIDAGAEYIVTQMFFDNEKFYEFVRKVREMGIDVPIIPGLKP
ITTLGQISMLPRTFFIDMPDALMDELEKCKTNADVKQVGIEWAIHQSKDLINNGIQVLHY
YTMSKAEATYRIAKEVF
>A0A1S9N1L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium beijerinckii|TrEMBL
MIKELLKDNILICDGAMGTYYSEVTGNDVSYCEFGNLNDKETIKRIHKEYIEAGAKLIRT
NTFSANTYDLGVSLETLMDIIKSGINLAKEVTRNTSVLIGASIGPIKTDNLDEFSNEVLE
EYKYIVDCFLENGIDIFIFETFSNYNYLKKISEYIKYKNTDSFILTQFAVKPDGFTRDGL
SAAKLIKEVRNTKYIDAFGFNCGSGPAHILEIVKKIDIENEIVSVLPNAGYPEIIHERTV
YPNNPLYFAKKVNEIRSYGVSIIGGCCGTNPSYIKQLTQIVNENSNVVNANTKSEPKVKS
FEKKAKNTFKDKLENGEFVVAIELSAPIDTDISRIIDGAKICKENNIDLVTVPDSPMSKV
RADSTIISSKIKREIGIEAMPHICCRDKNTNAIRSSLIGSHIENIRNILAITGDPISDAS
KVETKSVFNLNSFRLIELIESMNEEIFKEDSIYVGGALNLNVLNKEVEYNRMMKKIEKGA
KFFLTQPIYDDNAIEFLKMIKERTNVKILAGLLPVVSYRNAMFLNNELPGVTIPDKYVQM
FSENMSKEEAQEIGVKITVEIGKKLKNIADGLYFITPFNRVNMLIEIIKQINA
>A0A806ZU09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas synxantha|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKVLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTHYQQAGIQRIVALRGDLPSGMGMASGELRYANEL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7S2IL99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alexandrium andersonii|TrEMBL
MAAHADDAKISDLVANTPPGWFSFEYFPPKTDEGVANLRKRIVRMKQLKPLFTDFTWGAG
GSTSELTLQLTSAAKNEFGCVANMHLTCTNQKSEMCGEALDACKAVGVRNIVALRGDPPR
GQEKWTATE
>A0A840SL86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amaricoccus macauensis|TrEMBL
MANTSKALPSLSFEFFPPHTPEGSLRLWRSVERLAPLAPQYVSVTYGAGGTTRDRTNVAI
QTIIERARLNVAGHLTCVGATREETLDVARGYARMGVRRIVALRGDPPKGETTFTPHPDG
FASAAELVEGLKTVGDFEIAVGAYPEAHPEAVSLSADIDNLKRKIDAGGSAAITQFFFDN
DVFLRFRDACARAGISAPIVPGILPVENFGKMLNFAARCGASVPGWMHKAFGNAETPEAA
YLLSVAIASEQCTGLAAEGVGHLHLYTLNNPDLAYDVCRAIGYVAAPLAVAESGAA
>A0A7X0PDP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax soli|TrEMBL
MNAAKAQATGFPVSLEFFPPKTPAGADKLRAERQQLYALNPEFCSVTYGAGGSTQEGTFS
TVREILAEGVPAASHFSCIGATRESVRAQLAELKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLRAYLAKVQAGADVAITQYFYNAD
SYFRFVDDAQALGASIPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDRLRSAGVPALHFYTMNQSAATLEICRRLVL
>A0A3D8HNT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. MIT 99-10781|TrEMBL
MEAKNLSVDLESLIAKLHTNAPFLSLEITPPLSGKIEVDSIKELKNLDYINAFVCTDSPL
ARFKPSSILSSLKLQNFLQKPLICTLSMRDRNSIALCGDILAVNELGVRAFLSLTGDSIK
LGDCIESKGVFEDNSLKLARIIDTLNSGYGINHKPLSAPVQKIYNFHVINSYANNMESLK
TKLAKKLSNSDVEGFFTQPVYDEKSGEFLLKSLERLNSEYGRKSVLIFGFYPILSYKTAL
FLRDKLPGVFVPESLIESLESASKISKQEEEKVGFEQSVILLQKLQKLNNKIHFMNPQKI
ALFAPYFRV
>A0A6P5J519|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phascolarctos cinereus|TrEMBL
MAELPYMSHPRSRVCRHGHCCWSLGKGSQETGSLCFSVPPSISCRNPAMVNEARGSSSSE
GSSSGSEGSKDSSRCPTPVLDAERHERLREKMHRRMDSGDRWFSLEFFPPRTAQGAVNLI
SRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVDYCGLETVLHMTCCHQTRDE
ITSNLHKAKRLGLKNIMALRGDPMGDEWEEEENGFCHAVDLVKHIRSEFGDYFDICVAGY
PKGHPEAASFEEDLQHLKEKVSAGADFIITQLFFQADTFLNFVKACTAMGITCPILPGIF
PIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVAMCQELLASGLVPG
LHFYTLNREVATVEVLKRLGIWNEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYR
TQAWDEFPNGRWGNSSSPAFGELKDYYLFCLKSKSPREELLKMWGEELTSEESVFQVFTY
YLSGEPNQSGHKVTCLPWNDEPLAAETSLMKEELQKVNQRGILTINSQPNINGKPSTDPI
VGWGPSGGYVFQKAYLEFFTSSETVAALLQVLKKYELRVNYHIVNVKGENITNAPDLQPN
AVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYH
LVNLVDNEFPLDNCLWQVLEDTFELLSRPAPQ
>A0A174TGJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium baratii|TrEMBL
MNIRELFDSKRLVLSFEVFPPKNTSPVKTIYKALNELSTLKPDFISVTYGAGGSLINNKT
SEISSLIKNVYNIEALAHLTCISSKKENIDDITERLELEGITNILALRGDNNENEVGDYK
YATDLIKYVNEKKKFNIISACYPEGHIENKGIEVEIMNMKRKIESGTSSFISQLFFDNNI
YYDFLDKARESGVNVPIQAGIMPVVNKKQIDRITSLCGATIPLKFKKIMEKYEYDSEALR
EAGIAYAIEQIIDLASSGVDGIHLYTMNNPYVARRIKENIEVIVKSINNKGETIA
>A0A1F4QZL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium RBG_16_48_16|TrEMBL
MTLREKIESNRFILCGEIGPPQSCDGDFIREKSRHFKGFVDAVNITDNQTAIAKLSSIAS
AKILLDEGVEPIMQMTCRDRNRLAIQSDLMGAAALGLRNVLCLTGDYQTFGDHPEAKGVF
DLDSIQLIAAVAKMNSGFLLSGREMKKPSEFLIGAAANPFAEPFEMRLIRLYKKVNAGAR
FIQTQPVFDLETFSRWMEKVVEMGLAEKAAILAGVMPPKSAKTLLIMKAEVPGVKINEEY
IQRMKNARDPKEEGVKMAVEIIRTLKQMKGVRGIHLMPVLWESITPVIVKEAGLNSLNEN
TT
>A0A2M9NYV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. mrc49|TrEMBL
MNFRKELKERMLVGEGAMGTLLYSYGIDQCYEELNCTNPGQIESIHRAYLEAGADILQSN
TYGANFNKLKRHGLEDEVSKINRQGVILAKKAAQGKAYVFGTIGAQRSIRKSDLSMEEIK
RGFREQLYSLLMESPDGILLETFYDLEELETVLEIVKKETELPIIANVSMHELGNLQNGI
HLNEAFQKLEQLGADVVGVNCRLGPHHMIRALEEVSLPKHASIAIYPNASLPDYVDGRLV
YKAVPEYFGSSALDLRKQGATIIGGCCGTTPLHIQAVKNAVGSLVPVKEKLTKPREIEIM
EISDRAGELPLYEKAKTERTILVELDPPKKLGIETFMAGAKALKTAGVDSITLADNSLAS
PRISNEALANLLKDQLNVKPMVHITCRDRNLIGLQSHLMGLQTVGLNEILIITGDPSKIG
DFPGATSVYDLSSFDLISMVKQFNDGLSYSGQSLGQRANFKIAAAFNPNVKYLDKAVQRM
EKKIACGAHSFLTQPIYSIQQMEEVHEATKHLETPIFIGIMPLTSTRNAEFIHNEIPGIK
LPDNVRRAMALAGNDPVKARIEGVSIARELVDAARDKFKGIYLITPFLRYEMTAELTKYI
RKADSKQTSEVAVHE
>A0A3R6SJ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. AF15-21|TrEMBL
MNIKEYIKEQRLITDGAMGTYYEEKYSEDTVIAEKENLKNPEQIKEIHLEYLRAGARLIR
TNTFAANTMFLADMQEVKETVRAGYEIAKEAVTAFQAENGKEIPVFIGADLGPIYDLDHQ
DYDNVLQEYKEICDTFLSCGADCFVFETQSDFTYIEPVTAYIKEKSDAFILVQFAFDKSG
YTRSGLSMQRVAVEASEMENVDAYGFNCELDSTHMYQFMKNLKFSSDKFVSALPNAGYPY
TLRGKTIYSNNASYYAEKMKDIAALGTDILGGCCGTTPEYIALLSGELQDVPKAAKKIEN
VVTQEVTRTPSIFEEKLSRGEKAYIVELDPPFSEDASKVMKGAEDLRKCNVDLITLSDSP
MARARMDAGQLAVKIQQKTGVAVMPHISCRDRNVIALRAGLLGMHMNDVRHFLIVTGDPV
SRADRERVTSVFDFNSIKLMQYVKEMNLEVFAQEPVYYGGALNYHGANPDAIIERMKRKA
EAGCGYFLSQPVYTEKDVERLTYIKEHIDTKIMCGIMPLVSYKNAMFVKNEMPGIHVSDE
IVNRYREDMTREEAEEVAIELSVEIAAKLYDIADGFYFMTPFNRTGLIARIIEAIRQEEE
RR
>A0A413RYA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola vulgatus|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNCYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKDGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNMEQDLYWLKKKVEAGADYVVTQMFYDNRKYVDFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAMKCKDDKEARALGIEWCINQCRELIAYGVPGIHF
YTVGAVDNVKEVATAVY
>A0A7R6WCV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloprofundus sp|TrEMBL
MTNTTTNADLFSFEFYPPKTEEGANNLEQVHRDLAKLNPDFFSVTFGAGGSTRDKTYDAV
VKIQETGVAAAPHLSCVASTKENIRDILQNYREHGVSKIVALRGDLPSGMMSAGEFRFAN
ELVEFIRAETGDHFQIHVAGYPEVHPQANNANEDFANFKRKVDAGADAVITQYFYNAEAY
FYFLDKCAKSGIDIPIVPGIMPVTNYSQLFRFSDMCGADIPRWMRRTLECFGDDRASILA
FGEEVVSKLCQQLIDGGAPGLHFYTMNQSKPTLAVWNNLNLD
>A0A2H9RJH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeum sp. CG_4_9_14_0_8_um_filter_32_206|TrEMBL
MSLLRENFSRKFTATGEVSPPPCPDKTLFAREVEEMKPLMGRILGVNVVEGPGGRVLMSS
LGASIYMIQHGVEPILQQVVRDKNRVALQNDLISASIFEIENVLSIAGDHPACPASDNPK
SKPVYDMDSTTLIVMLKKLNEGKLWNGKDTNYENKNLNAKTNFFIGTGLSPTSSPLDGEI
YKVKRKLIAGCDFFQTQGVFDIEPIINFLNLYEKTIGEKISDKILVGIVPIWSYGMMKYL
LTLPGIVIGEKFRNDVNEARKKQKETGQKGLIEEIGVNLCVDLVDKIKGLGVKGVHIMPV
GNLHAMKEILDKSGL
>A0A8E0MG96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei subsp. paracasei Lpp71|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A8E6NR50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Paratyphi B str. CFSAN000540|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7I8VII6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dimorphilus gyrociliatus|TrEMBL
MSSECNNKGFEDSSSSGISDDERLPNQPKLPAKRYRRLIDRIQDRISHGRRWFSLEFFPP
RTANGAANLVGRFDRMSAGSPLFCDITWHPAGDPGSNKPTSSTMIASTMLNFCGMETMLH
LTCCGQTREEITKHLQKAKDMGIKNILALRGDPPENQDEWVHVENGFNYATDLVKHIREE
FGDYFVICVAGYPSGHPDCPSYEEDLLHLKEKIDAGSDFIITQLFFKADNFLKFVADCRK
IGINCPIIPGILPIQEYRSLRHIVKLSKLEVPQEIIDSINPIKENDEAIRNFGIDQCVKL
CRQLIDAGVHGFHFYTLNREVASIEILKAIGLWSVDPQRSLPWKRTANHNRCQEDVRPIF
WQLRQKSYVHRTSEWDEFPNSRWGNSSSASFGQLTDHHIFYLSNRMSKEEQLKMWGEELT
CEKDIFDVFHSYITSSKNKQGNLVSKIPWNDENIQPETKIILQDLADINQKGVLTINSQP
NVCAAPSSDPQFGWGNSNGYVFQKAYLEFFVNEKFATTLKEVLQDYPNVNYHIINAQGQQ
FTNCHEFQPLAVTWGVFPGKEIVQPTVVDPVAFTFWKDEAFSLWKEQWGKIYSPDSKSRK
IVEHIHDTYYLVNLVDNDFPKPTCLFEIVLKMLKTANEKFDPNLSDREYFIESVRLLRKV
FTESREFNLNEFDLNTTLLYWLPHKTELLEVFHPRNCEDHTYEIVQLLLITAIIERFLGN
LLLTKQNQCPSLLKDLLKSENLSKILNPNFLHMLQILIGPPISLNLRNLAWHGFISSLEA
IELRFAKFLMIILLKMNESVRNLKMEYNEIRLLYNLRKYDFELKQMFCKGLSLCEKLNIF
EEYTNANGFVSTNMKDQFHLAIRLMKMEKYWCVAIILIPQLELSLRRMFVLFNKCSERLL
TAEDSTLFTTLDENLLLDLLVYPNGPRLRDRLSHGEILLESFDNAIMHILLDIFLQIFHV
QRELGEFSTDIAVNFQEILTFHNNYQSLFHPINCCRNELNKILEEFGMENVRNQLLMVNE
DVQIEIKTVHRWRFRLKHEEITTEEEMINLFRKLISIITQLNKEINESYSEKCRQRDSNQ
LRSRQRSTLERMEKCLPKMKHSFKETIRLVGEAFKHFIIEKIKISQASYKKMKQLEKLWD
KISATVLKNKWEIIDELVDEFLEGINLDLRSSSVY
>A0A248THI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytobacillus kochii|TrEMBL
MNFLEKMKNQVLIADGAIGTLLYSYGTDTCFEELNLSAPEQIQHIHQAYLHAGADLIQTN
SYAANYLKLKRYGLEDSVKEINSAAVKLARSSIQQHQAYVLGTIGGVRGLNPLSIPLDEI
KRNFREQLYCLLLEGVDGLLLETYYDLEELETVLSIARKETDIPIIAQVSLQEIAILQNG
TLINDALKRLEAKGADVVGVNCRLGPHHMLETLSSVELPQHAFLSAYPNASLPAYIDGTI
QYKESEDYFRKSAKSFLKQGVRLLGGCCGTTPGHIKAFADEVRHAVPIIEKQVTNKRKPK
IERITIERTNTPLETLVQEKRTIIVELDPPKKLSTAKFFEGARALKDAGVDAITLADNSL
ATPRIANEALAHIIQKDTNVRPLVHLSCRDRNLIGLQSHLMGLHTLGLHDILAITGDPAR
VGNFPGASSVFDLSSFELIEMIKQFNEGISPSGSELGENAVFSVGAAFNPHVKSLDKAVA
RLERKIKAGADYFVSQPVFSVTQLLEIHEATKHLSAPIFIGMMPLISSKNAEYLHNEVPG
IKITQTTRDRMAKAVNPVLAEKEGLLITKELIDAALELFQGIYLVTPFLRYQLTTELTNH
IRRKDQQMKEHHYVKSSHH
>A0A0H3G3R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella suis biovar 1 (strain 1330)|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATCEDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A5N8VFZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces adustus|TrEMBL
MALGTASTRTDRARTVRDMLATGKTVHSFEFWAPKTEKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRSGTVRATEQIASDTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMADWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWESDVAHFVD
KCRAGADYAITQMFFEPESYLRLRDRVEAAGCATPVIPEVMPVTSVKMLERLPQLSNAAI
PEVLKERILTAKEDPAAVRSIGIEYATEFCARLQAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A180G623|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia triticina (isolate 1-1 / race 1 (BBBD))|TrEMBL
MKKVVELIEGLKEDEVYFTFEYFPPKTIDGLSNLYARIQRMANLKPTCAHVTWGASGSTS
DTSLEIAAMVQDQLSIPACLHLTCTNIQRSHLDQTLSQAKESGIVNILALRGDPPRGTEH
WIPTDHEFQHAIDLVKYIRKQHQTHFCIGVAAYPEGTTEFDQDQELSYLKQKVDAGADFI
VTQLFYDVDIFLNWVKACRKLGINVPIIPGIMPIQSYDGFRRLTALCKTNIPDSIHAKLI
PIKGDDQAVRDFGVKLSTQMIKRLQANGFRSFHLCTLNLERSITRLVNQLGWCPGGIKHC
QPLLGPSVKIGTAEIVQGGLSVGWDEFPNGRFGDQRSPAFGLREGYGSSLTSAFSHLTTD
VHALWGTPTSLEDITNVFCAFTEGKLPSTPWSEEPLALETSSITPFLVQLNQNGWWTVGS
QPAIDGADSLDSVVGFGPEGGRVYQKSFVEFFIPQSHLEGLLSAVDDYNKDHPEGVAQLR
YYAGNCNQDHIRTNVAPCETNAVTWGVFRGAEVVTTTLIEAQSFKTWKKQAFDIWNDWAE
SFETNSSHQRLLNQIEDSYWLCSIIDHDFKQPEHLWSFLINHQQRLSTKQ
>A0A1H8W1F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. Snoq117.2|TrEMBL
MKPSLSFEFFPCKTEAGHEKLIATARQLAGHGPEFFSCTYGAGGSTRDGTYRTVRQLNDE
VGVPTAPHLSCVGDSKAKLRELLQQYQEAGINRIVALRGDLPSGMGLSGGGELRYASDLV
AFIREETGDHFHIEVAAYPETHPQARSFTDDVRNFVYKMEAGADRAVTQYFFNADCYFHF
VERVRKLGVEAPVIPGIMPITNYSKLARFSDACGAELPRWLRKQLEAYGDDTQSIQAFGE
EVMTALCERLLEGGAPGVHFYTLNQAEPCIAIWRNLGF
>A0A0J6KIN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium sp. LK1|TrEMBL
MTAQSRTFSFEFFPPKTPEGIAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLATVLEI
RSEGHAAAPHLSCIGSTRDNISAILNEYRNNGIRHIVALRGDIPSGMVAAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDINNFVRKVNAGANSAMTQYFFNADAYFRF
VDEAQARGVNIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRQRMQAYYDDSASIRALGL
DVVTELCDRLLQHGAPGLHFYTLNQAGLVSTIWQRLGL
>G6FB40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis CNCM I-1631|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNLIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTF
>A0A087CUW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium reuteri DSM 23975|TrEMBL
MHTPMFSLEVFPPKRNAPVGTIYDTLDGLEGLEPDFISVTYGHGTHTDRTATARIANTIR
NEYGIPAVAHLTALYSDRNKVDEALDMFEQAGVQAVLALRGDYIEGEEPVGVFEHASDLV
AYIRERKPEIKVFGACYPEGHYQSSSLDEDIVNLKTKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGAKSVRRMAERNASRIPDHLAVMLDRWEGDAEAMRAAGIA
YASEQITDLVAHGVDGIHLYSMNHPATTRRIWRNVQPLFSE
>A0A2K1NG62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrotoga sp. 9T1HF07.CasAA.8.2|TrEMBL
MKIVDLIKQSNKPVLSFEIIPPNVGESIDSIFNVVDNLIEFYPKFINVTKHANEIEYVEE
NGKIMKIIQKKRPGTVGVSASIKHRYNIEVVPHLICTGFNKYQLEDILIDLNYLRIENIF
VVRGDKKRYTWKETDEYEHASQLVEQIANMNRGIYTFPTKEHNSTNFCVGVAGYPEKHFE
SPNFEKDLDYLKLKVDMGATFIITQMFFDIEYYKNFVNKVRDLGIEVPIIAGIKPLGSKK
TLYNIPKTFHVNIPKSIVEEFEDAKSSQDEYIIGVRHAIKLIEQLLELGVPGVHLFTMGK
GKIVKDVLSAFKGIF
>A0A0N0RQQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium akiainvivens|TrEMBL
MKVTEHIENANGKTLFSFEILPPLKGQNIQSIFDGIDPLMEFNPPFIDVTYHREEYEYKE
LPSGLLERRVVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VVALRGDAVKSEIYFRPEKDGHNYATELVSQISNLNKGIYLDEELQNSACTDFCIGVAGY
PEKHMEAPSPDSDLYYLKQKIKNGAQYIITQMFFDNQKFFDFVAKCRKEGITVPIIPGLK
PIATKKQLNLIPHRFSVDLPDDLIMAVVKAKDNDAVKQVGIEWCIEQSKELVKAGIPVLH
YYSMGKAESVKAIAKEVF
>A0A416RVR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF19-29|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A0S4QNW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia irregularis|TrEMBL
MRESTTSNEQPARGFELICEIEPPTRPDLTHARHQIGVLSPVADAFLIPDNHIGRATVSS
IAVAHEVQTMGGRSIACVNSRDRNLLGLRRDLLTAAAYGVEEFLFVRGDKPSAGNRTGDL
TVRAMIDEARAAGEDPVFADMPAFRVGAAAGLRPLPAWKQAADFLFVQVSYSVDALLRWR
DAHPVELPVYAGVMVLASAGMARRLAATIPDIDIPDDLVQAVERDRAAGVEAACDQVLQL
RDSGAFAGVHLVPVSRYRQVAARLEDLL
>A0A380H9A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus saccharolyticus|TrEMBL
MQRSFSHIELPKQAYLSCYPNASLLDIENSELKYSDNAQYFGDIAQELINEGVRLISGCC
GTTPEHILYIKSAVQDVKPVKDKKVIPITKTATHKQTRILKQNLTTKVKNGPTVIVELDT
PKHLDTDTIFDNVGKLDESGIDAVTLADNSLATVRVSNIAATSLIKQRYDIEPLVHVTCR
DRNLVGLQSHLLGLSLIGVNEILAITGDPSKVGHLPGATNVYDVNSKGLTELALRFNQGI
NTDGDALKKHTNFNIAGAFDPNVRKLDGAVKRLEKKVASGMSYFITQPVYSKEKIIQVYE
ETKHLNTPFFIGIMPIASYNNALFYIMKCQASKCQKMY
>A0A1G3SLD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuricurvum sp. RIFOXYD2_FULL_44_160|TrEMBL
MFETFIDKLRNSTYITLETTPSRSAQFAPTIEKIAALGLDKLVDGFSTTDNPLAKLKYNA
LFAAMKLQDRFGLPTLATMSMRDRNRIALQSDLLGANESNVRAILALTGDSAHYSDQPHA
KGVFEGNSKLLLDIITTLNSGTDMAEQKLLAPVQEIYPFAVIDAYAKSAATLQKKMTKKV
AHGAIAIISQPVYDLENARKLLDMMEEANRENNANCVLVLGYFPITKLRTARFLDENVPG
IYVPHTWVEALEAASLISPEEEYRVGFELSKNLFEELKALHPKIHIMTANQFELAKAILS
>A0A832VZ35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina acetivorans|TrEMBL
MLFNFREKLNSRKFLVTAEVSPPKGTRYSVPLEDARHLKGRADALNVTDNQCSIMHMSSL
AFSKLLLDEGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDFPSCGDHPGSKP
VYDLDSVQLIELVRKLDSGFDLAGNILDGGTSFCAGAVSGIDPDKIIQLIKLEKKVRGGA
DFIQTQAVYDVGIFEEFMEAVNHLEVPIIAGLIPLKSLGMAEYMNKNISGIHVPDEIMLR
MKEASSPLEEGLLIASETIKELTKLSRGVHIMPIGSHKNTPRLLSMAGISEI
>A0A841V876|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. UCD120|TrEMBL
MYHTHSPTAFRRAVQAGEFLVTAEVAPPKGGNPAHMIQMAATLKGRVHAVNVTDGSRAVL
RMSSLIASVILSQNGIEPICQVACRDRNRIALQADLMGAHALGIRNILALTGDPVKAGDH
PDAKAVFDLEAVRLLQLIRKMNQGVDCNEKPLTDGALDLFVGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFDVLEKFMDTIASGYKKPILAGIFLLKSAKNAQFINRCVPGVN
IPQHIIDRLAKAKEPFEEGIKIAAEQVQIARQLCQGVHLMAVKREDAIAPILDLAGIAPV
NQLVSK
>A0A420YDQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coniochaeta pulveracea|TrEMBL
MDKITDKIAALPPDTDYFSLEFFPPKTAMGFANLRDRLERMSRALRPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRRLIDQALQDAKALGIRNILALRGDPPRRAE
YKDLNDPEPDDGEDEFVWAADLVRYIKKNHGDYFCIGVAAYPEGHADESHPMGQSLERDL
PYLVDKVSAGADFIMTQLFFDIKAYDNFEKTLREHPSGVFKDTIIIPGLMPIQSYQMIKR
TVKLSHARLPNPIMERLDAVRTDDHKVKLVGVDIVSELVEQIREIKNRTSSGPKGFHFYT
LNLEKSVSFIVERTHLIPPSTPEEGEEIAVDELTAAVPHLQVNGSTPTHTFKTVSRRSSI
GSDPRNRVIVTGNREIDNPDYEATALEASRPAQPVNTRANTLAISEGEGALGREATWDDF
PNGRWGDARSPAYGEIDGYGVSLHVTVPQALELWGTPTTTEDVNKIFMRHIRGELSAIPW
SEEGFNAETGKIRDELVKLNERGWLTLASQPAVNGLKSDDPTHGWGPANGFVFQKAFVEF
FIPNEDWEVLKKKLTRPEMKDAICFYAINARGDFVSSDTIADQNGEDSEAGHEYREPSTN
AVTWGVFPGKEIVTPTIVEEVSFRAWSEEAFSIWGEWAKVYGYGSESQKLLDGIRERSWL
VNVIHHDFVNTNGLWDLLLKD
>A0A2S5Q8U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp|TrEMBL
RAKLAKFNPEFFSVTFGAGGSTRDRTMDTVLEIQREGYQAAPHISCISSSKSEIRELLQA
YQAQGIKRLVTLRGDIPSGEVSAGDFKYASELVAFIREETGNHFSIEVAAYPEFHPEART
PAADLLNLKRKVDAGANSAITQYFYNADAYFRFVDQCDALGINVPIVPGIMPIYNITQLA
RFSSVCGAEIPRWLKMRLEEYGDDMVSLRAFGIDVVSELCETLLAWGVPSLHFYTLNQSN
IISNIIESVQD
>A0A1M4N1T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Donghicola eburneus|TrEMBL
MTAPRISFEFFPPQSLEASFRLWDTVQVLAPMEPRFVSVTYGAGGTTRDLTHEAVTTLHK
TTGLPVAAHLTCVNATREETLNIANSYAEAGINQIVALRGDPPKGTGGFKAHPEGFADSC
ELISALADTGKFTLRVGAYPEKHPEATDHKADVEWLKRKLDAGASEALTQFFFEAETFLR
FRDACADAGITAPIIPGILPIENWKGVKKFSAACGTSIPAWLDEAFDKAIRDDRQDLLAT
ALCTELCDELLQEGVEDLHFYTLNRPELTRDVCHAIGVTPQVKLQNVA
>A0A1I7NWR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium facile|TrEMBL
MAQTSERKSKLLGSGDILVSFEFFPPKTEKMEETLWSSITRLAPLGPEFVSVTYGAGGST
RERTHATVTRLLKETPLKPAAHLTCVDATKEEVDAVAKTYWDEGVRHIVALRGDPAQGTG
AKYEPYPGGYKNAADLVAGLKAIADFEISVAGYPEKHPESPSIEADIENLKAKVDAGADR
IITQFGFDNTHFLRFIERARAAGIWVPISPGIVPIHNFKQVAGFAKRAGASVPSWLARRF
EGLEDDSATSHLVGAAVATEQVMDLVDEGIKKFHFYTLNRADLVYAICHLLGLRSVRTAN
ADAA
>A0A5D3WMC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geothermobacter ehrlichii|TrEMBL
MGDLAIELVPRSREVLERDLATVRKHFPQVKTINIPDLLQFPLRAWEAGEIIAPQVGRVI
PHLRAIDFDLQADWPFLAAIRRSGCPAVLAISGDPPQDMLHRTYRTPVTDFIARLKRELP
GVKVYAGLDPYRSGVKAELDYVHAKLQAGADGFFTQPFFDLRFMEIWADLLIGLDVWWGI
APVLTEKSQAYWENKNNGFFPPDFEPTLEWNRQFTKRALHFVKARGASAYIMPIRADIKK
YLDGII
>A0A373L011|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. AF42-8|TrEMBL
MNIKEYIKEQRLITDGAMGTYYEEKYSEDTVIAEKENLKNPEQIKEIHLEYLRAGARLIR
TNTFAANTMFLADMQEVKETVRAGYEIAKEAVASFQAENGKEIPVFIGADLGPIYDLDHQ
DYDNVLQEYKEICDTFLSCGADCFVFETQSDFTYIEPVTAYIKEKSDAFILVQFAFDKSG
YTRSGLSMQRVAVEASEMENVDAYGFNCELDSTHMYQFMKNLKFSSDKFVSALPNAGYPY
TLRGKTIYSNNASYYAEKMKDIAALGTDILGGCCGTTPEYIALLSGELQDVPKAAKKIEN
VVTQEVTRTPSIFEEKLSRGEKAYIVELDPPFSEDASKVMKGAEDLRKCNVDLITLSDSP
MARARMDAGQLAVKIQQKTGVAVMPHISCRDRNVIALRAGLLGMHMNDVRHFLIVTGDPV
SRADRERVTSVFDFNSIKLMQYVKEMNLEVFAQEPVYYGGALNYHGANPDAIIERMKRKA
EAGCGYFLTQPVYTEEDVERLTYIKEHIDTKIMCGIMPLVSYKNAMFVKNEMPGIHVSDE
IVNRYREDMTREEAEEVAIELSVEIAAKLYDIADGFYFMTPFNRTGLIARIIEAIRQEEE
RR
>A0A6J0INH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lepidothrix coronata|TrEMBL
MVNETQQSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAADL
VKHIRSEFDDYFDICVAGYPKGHPEAESYETDLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGHRVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQQ
>A0A7T9Z8N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia aeria|TrEMBL
MTTVHPALSYELYPPRSHASCDSLLKTITELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLALRGDIPPENTRPLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAARLAGVEIPIIPGIMPVTSLTRLTKLCELAGLEVPRELAHRLETASEP
REMHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>A0A1E1M3U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhynchosporium secalis|TrEMBL
MHIKDMLAEAERSGQPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
QLTCEMVSVAQSHHGLETCMHLTCTDMGQDMVDAALRDAYKAGCTNILALRGDPPREKEK
WVATEGGFQYAKDLVKHIRETYGSHFDIGVAGYPEGCDDQDDPELLLEHLKQKVDAGATF
IVTQMFYDAENFIDWIHKVRAKGITIPIVPGIMPINTYASFLRRCNHMGCRIPPEWSEAL
EKVKNDDSAVRNIGTGLVAEMCRKLLAAGIHHLHFYTMNLAQATRMLLEELNLTPSEQRP
RKQALPWRQSLGLGRREEDVRPIFWKNRNKSYVTRTQNWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNRMLWGEPKSIKDIAEIFVKYLENGVESLPWSEEPISSEADSIKSDLIA
LNRRGMLTINSQPAVDGAKSSDQVYGWGPNNGYVYQKAYLELLVSPTLMAQLITRIELEP
DLTYYAVNRVGELKTNASGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AKCYSALSPSRQLIENLMDTWYLVNIVHNDFHQTHGLFPLFDGLELKDIDVPFSSSVNGG
DTNGADTNGVHINGVNVIKPEGKENIHLTNGAPVKVSAAN
>A0A2N2RNL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-22|TrEMBL
MTKKFEVSFEFFPPKTSEGVDKLREARTQLARFNPEFFSVTFGAGGSTRDRTMDTVLEIQ
QEGFQAAPHISCISSSREEIRDLLQAYQSHGIKRLVTLRGDVPSGEVSAGDFRYASELVA
FIRAETAQHFTIEVAAYPEFHPEARTPSADLQNLKRKMEAGADSAITQYFYNADAYFRFV
DQCDALGINMPIVPGIMPIYNITQLARFSSVCGAEIPRWLKMRLEEYGDDMASLRAFGVD
VASELCGTLLAQGVPGLHFYTLNQSAIISHIIDNIAE
>L1Q301|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 326 str. F0382|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVESCKNNNEVKQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A1H9AJ08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodospira magna|TrEMBL
MKSQLRHERTFSFEFFPPKSEEGAAKLRETWTRLARLEPRFFSVTYGAGGSTQARTLETV
LDIHQHSGIAAAPHLSCIDSTAEQMRSILKTYMDNGLRHIVALRGDLPSGMREPGEFRYA
NELVEFIRRETGDHFTLEVAAYPECHPQAPSAFKDLENFKRKVEAGADSAITQYFYSADA
YFRFVDDCERMGIHIPIVPGIMPITNYKQLARFSDACGAEIPRWIRKRLEAYGDDLDAIR
AFGEEVVSRMCDQLLHEGSPGLHFYTMNQAGPVSAIWKNLGLTPQPE
>A0A220WB61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingorhabdus sp. SMR4y|TrEMBL
MNNPVRPLGLSELEEAKRALDAPLFAGLSGDADVSFEFFPPKSDKMEKTLWDSVVTLEPL
SPRFVSVTYGAGGTTRERTHATVARIARETDIPAAAHLTCVGASKAEIAEVAQSYWEAGI
RHIVALRGDPPSEGQAFEPHPQGYASAAELVKGLTDIAPFEISVAAYPETHPEADCPQSD
LDNLKRKLDAGASRAITQFFFTAEAFFRFRDAAVAAGIDAELVPGILPVSNVAQTRKFAG
MCGAEIPAWMNDLFEGLDDHPSARQLIAATVAAELCRKLYAGGVRQFHFYTLNRAELSYA
ICHLLGKRPGSAKQEKTA
>A0A1F9CRM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_54_11|TrEMBL
MKEESRLKNVLQGGHFAVTAECGPPKGADPKAIQKKGKMLKAFVDSVNVTDNQTGVVRLS
SLAACALLLKDGLDPVLQMVTRDRNRIALQSDILGASALGIRNILCLSGDHQSFGNQPQA
KGVFDIDSMQLIQLVRQMRDKGVILGGERLTEPPHLFVGAVENPFADPFSYRVLRLEKKV
AAGAEFIQTQCVYNIVRFKEWMEQAGDCGIPEKVYILGGVTPLKSTRMAEYMSKQVAGMD
VPDEIIKRMKSVPADKQREEGIRIAVETIQALKGMKGIHGVHIMAIEWEDVVPQLVEEAG
LAPRPTV
>A0A544QW54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptacetobacter hominis|TrEMBL
MSRLKDKLESGKFAVTCEVAPPKGTDLTHIKESIEILKPFVDAINVTDFQSAVVRASSLV
VCRLLIDNGIEPVFQITGRDRNRIAIQGELLSAGICGIENVFAITGDHTSKGDHPQAKNV
FDLDSINILRVCEKISAGTDMNGNKLDGNPVFYAGAAVTPSFSPIEIQIIKMRKKIKAGA
KFFQTQAVYDIETARRFRELTKDFDCKILIGIVPLKSPKMAQFLNNNIPGIEVPDEIIER
MEKAGKDNFRSEGIKIAGEFIKKLKEENLCDGVHIMPVGAEKSVPEIIRIAGIYD
>A0A1D9PTS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)|TrEMBL
MEKITEKIAALPPDTNYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSDE
YRAVDEKNGDLPAMDWEFEWAIDLVRYIRKQYGDYFCVGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVDAYDTFEQRLRDHPSGAFKTIPIIPGMMPIQSYQMI
KRTTKLSHAKLPTNIIRRLDEVRGDDEMVKKVGVDILSEMVEHLKSTKSQYSGPRGFHFY
TLNLEKAVSFILERTELIPDAETVAALEPEYVPTIPDIADLLSIHSGSHRRSSRRRSSVG
SDPYNRIIITAPQTSNPSFEATALEAGVPAEAVNSRANTLAISEGEGSLGREATWDDFPN
GRWGDARSPAYGEIDGYGVSLHMSINQAIKLWGHPSSRADITDIFIRHLEGQLTAIPWSE
EGLNEETNSIKKQLLSLNKKGWWTVASQPAVNGVKSTDSIFGWGPKNGFVFQKAFVELFL
PTSDWEALQAKLTSPALRDTVSFYASNAKGDFISSDEAIGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWARVYGKDSETRKVIDGIKEDVWLVNVIHHAYVEGEGLWDV
LLN
>A0A0S4IQK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bodo saltans|TrEMBL
MSEGHQVSFDEKIRQRSCGVITYGMTPPKLSTEVSKLPALADTHRQRLLNIPVDAVILYD
IHDEQDRAAAVPRPFPFSETVDGFDWADRLGDVGKPFVHFRCIAKYDAVAFASQLRDRFS
PHAVVIVGGAAAAQQLPITMDEAYRIRRDVAPAVLLGAVAIPERHAAKGNEHERMITKQV
EGGASFFVTQCVYSLEEAKNLLSDYAVLCREKNIPMLPILVTLTPCGSTKTLTFLRWLGV
KVSKWLENDLRDAADDGDILEESVDALLALLKELAHFARRKNIPLGCNIESVAVRKAELE
ASIRLLTNAQLILEEVFHDARSKQSVVVHQ
>A0A7Y2ZLZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
PPLKGQHIQSIFDNIDPLMEFNPPFIDVTYHREEYVYKELDDGLLKKQVVKKRPGTVGIC
AAIQNKYHVDAIPHILCGGFTKEDTENFLIDLDFLGIQNVMALRGDPVKSETYFRPEKEG
NNFASDLVSQINDLNNGLYLDEELLNTSKTGFCIGVAGYPEKHLEAPSLDSDIHFLKKKI
KKGAEYIVTQMFFDNKKYFEFVDKCRESGITVPIIPGLKPIATKKQLNLIPHRFNVDLPQ
DLILEVVKCENNEDVRKLGIEWCVEQSKELKAAGIPVLHYYSMGRSDNIKAIAKEVF
>A0A7X6XLP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MGPNALRAALTRGEFVYSAELVLGRDHAIPDAEQFVADAAATAEGIRVISATDLPGGNPA
LPPEAFVAAVQAQGLTPIAHLTGKDGNRAFLEGRLHALARLGVANILCLTGDAHKDGFAG
AAKPVYDLDSVLILDLVNAMRAGLPYSVGPRQAQTTPFDFFPGAAVNPYKTREPDQMMQL
FKLELKIASGAQYIITQLGYNLRKLYELKQYLRREGLEHIPVIPSIYVPTATIAKLMRAG
EVAGCVVPDALIQALEGEKKPQRLERAALMVAAVKGLDFAGAHIGGFGLSHADFMTIRER
AAEIGDGWRDRLDELILEVPGEYYLFPKGKDGFSDDTQPYQIGTMPYGLSFTQRLCRAIN
QLMIAEGSPGARFWAARLRGDTKAEWRRGFWYQLLAAADVFKRRTFGCVQCGDCVADYLG
YTLCSQGRCYKELRNGPCGGSRIDGTCEVNPDQQCVWNLAYLATLAQHEDPRKFAETLVP
PRDWSLNRTHSLANHYKHLDNTPKRKSVSASKEPPPDE
>A0A241VUL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4558|TrEMBL
MSELSQYFAQNKFCILVEYLASTRIFPVRTSLADFPTMMTLADRVHSDDDLVPLEAAKLY
SQHSEKVLHYAGKGRDIAEFELFLKKAKLQNIQNVLLLSGDKLKQHQSGTHYTERTRYLE
SVNAVMVAKQQGGFCIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIITQLGYDLAALK
QAKQFLNQNHYSQKMLACVMPLSLARAKFMLKQKVAGIVITPHMLQVLEKEKQIGLTDRV
YRRCALQILLCKRLGFSGVHLSACYQPEEQLKLEQYIHEYQHLDFQACEKLWNDLWEVAT
GKEFEPALVYFSKPARSTEILKYQHLHFLHETLFNSRFGRGIGQFIFDHQFWNKKIAIQS
LLKTELMSKHRMVGCESCGQCRLGETLYICPETCPKGLANGPCGGTTLDQCEFGDRECIH
SVKARLAKAVQQIDILKDELIPTVPIEMRGTSSWKNWYIHQS
>A0A7Y5NP06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polyangiaceae bacterium|TrEMBL
MASDLSPSLIPFLEAVEKGLLVSDGAMGSLLYERGVFVTQNFEQLNVARPDVVKKIHADY
LEAGAQIIQTNTFGANSFRLDRHGLVGEVRRLNIAGAAIAREVVGRNAYVAGSIGPTGLV
PGPNRAKELTAARATFAEQAAALAEGGVDLFVIETFRHLDELGIAIQAAREVAPKIPIAA
TPTFDSEGTVADGTPPEEVASILRDFGPDIIGVNCGDGPQLSLTMAERMRRAGLPLYVQP
NAGLPRSVDGRLLYMATPEYFDVFARRMIQAGARIVGGCCGTTPEHIRWMARSVRMLGSA
LSQKTQSVPPYELKGGHPNAVEPTPLKQRSEFAAKIADGKFVVSVEVNPDPGTSPENALA
AAKMLIDAGVDIVNVADGPRATARMSNLAFCALLLERHGIQPILHVCGRDRNMLGQMAHL
LGAHALGIRNLVVITGDPPKVGDYPEATAVYDLDSVGLLHMASKMNRGLDPAGKGLRGGK
TEFCCATGFEPGAQDLDREIARLEAKVAAGADLVMTQPVFQQELLDQVLRRIAHLKVPVL
VGVLPLVSFKNAEFLHNEVPGMQIPDEIRERMRAAPPGAEARKEGVRIAREMLFAVRDRV
QGAYLMPPLGKYELALEVLDGLNR
>A0A8J3DNZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corticibacterium populi|TrEMBL
MIHIPASIEIVPKQALESAELPGLFPAGTRVYVTDIGTDTVEDLTAAAKRVRDLGYTPVP
HFACRRLTTRAALEDRVKRAATEAGVTDVLVIGGGLDKPAGEFASAMEVLNTGVFERNGI
KAMGVAGHPEGSPDFSLESAMQALREKQAFADRTGIDVRIVTQFGFDPTKFIGWADSLRA
EGINLPVHLGVAGPAKFPTLIKYAAMCGVGNSIDFLKKNALSLTALAVGHNPEEVVGPIE
ASSRRPSSPITQIHVFPFGGLKKSAEWLVKRGSWDIKTSAYPSALFA
>A0A7Y3LC20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTSILQRIRSPEPTFSIELWPARTVEATVRLNAALPVITSLEPTFMSITYGAGGSTRDRT
HSLVVRIVHETGLDAVAHLTCASHTRQELEWILDRYRRAGVSTILALRGDPPLDGQSELK
DGELKHAVELVRLARQTGDFTVAVAAHPEGHPNASSRAEDEGHFVAKLEEADFAISQFFF
TEDVYLDFVERVRAKGATKPILPGIMAPKSVNGLFKMSELSGASIPAPMRAEFLRFADDP
VSIRRLGVDVAISLARGLLEAGVPGVHIYSMNSLESTVEIHEGIADLLVVE
>A0A5A8CD90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cafeteria roenbergensis|TrEMBL
MAARIDELMAAHSGDAPWVAFEYYPPRTEDGVNNLKKKMPRFKAQKPLYIDMTFGAGGST
SDLTLDLCKEAKAAGLEPNMHLTCTNMPQEKIYEALEGAKAAGIRNIVALRGDPPLGQER
WEAVEGGFTCALDLTKHIVKTYGKDQFCISTAGYPEGHPGAIKKVAEGQELSDKEKRRVV
SLEDGDYVCSDADFAKEMEYLKAKVDAGASLIITQMFFDVDVFADFLEACKEYGITVPVI
PGLMLVQNAGGFGRMTAFCKTRVPTSIREGLEAVKEDDAAVKQFGIDLGAKMCEQLMALG
CKGLHFYTLNLEKVTFGVMRKLGLFDEDAAAAAAAAAEPAAAASAGAASA
>A0A8J3GJX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corticibacterium populi|TrEMBL
MNQPSFSRRPDIGERVRVSFEFFPPKTAEMETRLWDTVKRLEPLQPHFVSVTYGAGGSTR
ERTLRIVRRIIAETGLAPAAHLTCVDASRAEVDEVIASFLQAGVTRFVALRGDPSAGVGA
TYEPHPGGYTNGAELTAALQRQGATDISVSAYPEKHPESPDFATDIDMLKRKVDAGATRA
ITQFFFENDDYERYVERARRAGIYIPIVPGILPIENFRQVANFAGRTGATIPAWVAQRFE
GLEEDRQTHALVSAAVAAEQVLDLVERGVEDFHFYTMNRAELSFAICHLIGVRPVEAAAV
QPAAAAA
>A0A260E5X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 06-156-3|TrEMBL
MDRLRSDGAARIPFSVEFSPPRDEAGEARLWRAVREFEQLQPAFVSMTYGAGGSTRDRTV
RVTGQIAEETTLLPVAHLTAVSHSVDELRSMVGSYADRGISNILVLRGDPPGDPLGDWEK
HPDGVEYADELVTLVRELGDFHVGVASFPEGHYRALNLEQDTQVLVNKLRAGAEYSITQM
FFDVDDYLRLRDRVAAFDPEQGAKPIVPEIMPITSLRTVRRALALSGSALPKALDDRFTA
AAGTGREEDRAAVREVGIELATQIGERLIAEGAPALHFITLNFAKATREVLTNLGLCAAR
V
>A0A2E0E126|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MKPNQKKLTNKTNNKSTQLRLLKEMTYELIPLKNVHEQGKHLPESSTISITCSPAKDIEA
TLELCENFLDNGHSTIPHFAARMVESEEHVTQIVKRIETLGIETVFIIGGDADQRGPFTX
APSLLRSFLDKTPNIKTIGIGSYPDGHPSIPESALADSLVKKQEMIYESGLNGYMATQMC
FETETISNWLKSCRKAGVTLPCHLGLPGVVDMKKLINISLRLGVGVSSRYLKKNKKTVFK
LLSPRGYNPNKLIVPISNHAEELEITGVHCFTFNAVESTEAWRTKAMGRLV
>A0A2G2GHR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robiginitomaculum sp|TrEMBL
MTIQKPNTQHATNLRVSFEFFPPKTDKMQKNLWASIQKLETLRPDFVSVTYGAGGSTRER
THETVAKIAKETRLNAAAHLTCVGSERAEIDEIAQAYWDAGVRHIVALRGDPEGGLGAEY
TPTKNGYAYGSDLVTGLRDIAPFDVSVSAYPELHPESQNWSAEIDNLKRKVDAGASRVIT
QFFFNADTFLRFQDKVMDAGIDIPIIPGLMLQPNYKGLCRMSKMCNISIPDWYHDLFAGL
DDDPQTRQMLTATTAADLARKLQKGGVRRFHFYTLNKADLAFMVCKFIGIQPK
>A0A0L0G039|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaeroforma arctica JP610|TrEMBL
MVPAKLSRVPSDPNLRNIPKIVDKINLRKSEGKTFYSFEYFPPKTTEGAQNLYARVERMS
SVEPLFVDMTWGAGGSTSEMTLELCTNIQTYLGMDVMMHLTCTNMPRSMIDNALTSARAN
GVRNILALRGDPPAGQDWQACEDGFAHATDLVSYIRQTHGDYFCICVAGYPEGHPAGSLD
GKITYEEELQFLKQKIDAGADVIITQLFFDTDLFLEFIDKCREIGIDTPILPGIMPIQSY
AGFHKMVGFCKVKVPQFITDQLEAVKDDDAKIKELGVRIGVDTCKKLLESGKVPGLHFYT
LNLEKMVMSIIDGLQMVPTDKAIRSLPWRPSTADRRRSEDVRPIYWANRPKSYLSRTATW
DDFPNGRWGDRRSPAFGDVGSYYIFNPSRMYNPKVKETYGPCDSIDAIADVFVKYLSGGI
KVLPWSETEMIAIETAQINDDLLWLNQNHLFTINSQPRVNGVPSTDASFGWGPEGGYVYQ
KAYLEFFATKDIVDKLFEAVKTMPSFTLYAASKKSKSIMTNAKRPDTATAVTWGVFPETE
VLQPTIVDPASFMAWKDEAFSLWLDVWMSMFNLPEEQKARDTIKYINEEFYLVNVVDHDF
RDGNIFRAFDGILPAKSA
>A0A5C5S1Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tsukamurella conjunctivitidis|TrEMBL
MTEQSRTVLDRLDAVRASGRMPFSVEFMPPRDEEGEARLWRAVRTFERMDPAFVSMTYGA
GGSTRDRTVRVTGEIAASTTLLPVAHLTAVNHSISELRALMGSYADQDVRNVLVLRGDPP
GDPLGPWVRHPQGLKYACEVVELVRELGDFHVGVASFPEGHHRSPNRESDVRYFANKLRA
GADYSITQMFFDVDDYLRLRDEVTAFDPEQGAKPLIPGIMPITSLKSVSRMAELSNAKIP
DAMRDELRAAAGDGPEEDRAAVRAVGIEIATRMGERLIAEGAPALHFCTLNFAKATSEVL
ENLGMLPVGV
>A0A160BT55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia mannitolilytica|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRENIRSILNTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVAF
IRQETGDAFHIEVAAYPEYHPQSRSPRHDLDNFARKVKAGANSAITQYFFNADAYFQFVE
DARKVGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLESFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNTATATRAIWQRLGL
>A0A268TWD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. 13S00401-1|TrEMBL
MDIESFLLDLKNAKKRTITYELSPDKSALLDTLAQKVLESKLLHHVSGFVCTDSPLARMR
QSSLLSSIKFQALFNKPVICTTSLRDRNSLALSSMLLGANGFDIRIFLALSGDALKLGDQ
PQAKSVFEGSSLKILELVKALNEGYDLGGNALKYPLPKPIYAFSTISSYAKNKALLKKNL
ESKIALGASAIITQPVYDLATLNELLEWVDEINNKLAKSAILVPGFFPVLSLKSALYLNS
KLPGVSVPASLIERMQEAALKGSEKEVGFELSLKLLESFLNIHKKCHFMNSNNAGLASSM
LALI
>A0A348Y436|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVIEHIERANGKPLFSVEILPPLKGQDVNATFKTLDPLVELNPAFIDVTYHRQEYIYKQ
KENGLLKRYQVRKRPGTVAICAAIQNHYKIEAIPHLICGGFTKEDTEDALIDLNFLGIDN
LLVLRGDPIKSEKSFVPEVGGHAHASELIEQITALNTGNYLDDELQESHAMDFCIGVAGY
PEKHFESPNLAMDLYYLKKKVELGADYIVTQMFFDNQKYFDFVKKCREMDINIPIIPGIK
PLTTFNQLTSIPQNFYLDLPEALAMEVLKSKDKERIKEIGIEWCIQQCKELIDFGVPGLH
FYTMSNSINTKKIAEAVY
>A0A2E5ZDR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MANRLNNGSSRSDKPRADQDVQRRLLEGMTYELIPLKNLADQSRHLPEGATVSVTCSPAK
TVDDTLDLCAGYAKKGFTVIPHFAARMVEGEDHVDRIVQRIRDIGIRKVFCIGGDADPRG
PFTDAAGFLRSFLDRRPEIDVVGVGSYPDGHATIPDQALFDALLEKQEMVRQAGLQGYMA
TQMCFDATTIAAWMERRRAAGVDLPCHLGVPGAVDRAKLLTISIRLGIGHSARYLKKNKA
SVIRLLSPGGYNPNKLIAPLSGRADELGIDGIHCFTFNAVDTTEDWRLKSLKKLNR
>A0A378MWJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mannheimia haemolytica|TrEMBL
MQKLYLLVQQKWRMLWDSIDRLSPLKPKFVSVTYGANSGERDRTHSIVKSIQEKTGIISA
PHLTGIDATPEELKVIAKDYWDSGIRRIVALRGDIPKGYDKALFYASDLVALLKSVADFD
ISVAAYPEVHPEAKSAQADLLNLKRKIDAGANHVITQFFFDVESYLRFRDRCVSIGIDCE
IVPGILPVTNFKQLQKMAAVTNVKIPTWMGKNVRRVR
>A0A352BSK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKITEHIKQAKETLFSFEIIPPKKGNSIQDLYDNIDPLMEFNPPFIDVTTSREEYVYIEK
DGLFDRKITRMRPGTLGICAAIKHKYNLDTVPHVLCGGFTKEETEYLLVDCHYLGIHNIM
ALRGDAMKHQKIFEPTPGGHAYAHDLVKQVMDLNRGKYLHQVVEGSEPYDFCVGVAGYPE
KHYESPSMNSDLKRLKQKVDAGADYVVTQMFFDNAKYFEFVDKARAIGINVPIIPGLKPI
AVERHLQLLPQIFKIDLPEDLVAGVEKCQSNKDIRALGIEWCIAQSKELIQAGVPLIHYY
SMGKSSNIMEIGKELF
>A0A0H2Z502|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O1:K1 / APEC|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A511HJY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcus virescens|TrEMBL
MNPSDPCFSFEFFPPRTDEGEANLLKALEDLATLQPGFVSVTEGAGGSTRAKTVELVLRI
KQEAGIEAMAHLTCGGHSPAELRTVLERLSAAKVDNILVLRGDPPKGQTVFEPAPGGFRY
ASEMVRFIREEDFNFCLGGACYPEGHVETPSRDDDLRHLKAKVDAGLDFVVTQLFFDNAF
YFDFVERARRAGINVPIVPGIMPITNYEQIQRFTRLCGATVPMRLALQLERVKDNPEAMA
QLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRARS
>A0A2D5HXL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIENAKGKTLFSFEIVPPQKGKNIQELYDNIDPLMEFNPPFIDVTTSREEHIYIK
REDGLLERKITRMRPGTVGICAAIKQKYDVDTIPHVLCGGFTKEETEYVLVDCHYLGIEN
VMALRGDAMKHQRYFEPTTGGHCYANELVGQIKDLSKGKYLNEVIDSDNHADFCVGVAGY
PEKHLESPSLETDLKKLKAKVDAGADYVVTQMFFNNQAYFEFVEKAKQMGINVPIIPGIK
PIAVKKHLQLLPHVFSIDLPQDLIDNVEACKNNKEVREVGIEWAIQQTKELKEAGVPVLH
FYSMGKSSNIKKIAEAVF
>A0A3B0UUH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKPGFVEYLKDHVVLGDGALGSYLYEKGIERGRNLDLLNLQAADFVFSAHEEYIRAGSQL
IETNTFGANRFRLREVGAQHRVREINRAGAGIAVKAAGHQVYVAGSVGPTGLTFPLDEDE
VREEDIRQAFDEQIAALVEGGVDLIMLETFPCLDEILPAIAAARAVAPHLPLVAQMVFPA
RGMTVRGEDALTCGRAMAAAGADVVGTNCGRGIDAMATAVRCLAPLAREGIILSAFPNAG
MPEMVGHRMIYPAQPAYMAMRAGEMIRYGVHLLGGCCGTGPEHIHEFRSTLKIRPVRIPG
GRIIVAPDKTPETAVAVRPGGFLAGLQANRLPIIVELDPPTHLDVAPVLAGARALTEAGV
DAISLGDNPLATLRVGNLGVASLMRKETGIQTIIHQSGRDLNALALQARMMEAHLLGIEA
VLAVSGDSASATDQPEVSGVFDLRSYGLLRMLRQLNGGLNMAGRSIKHKTNFSVGAAFSF
RQDNPQLQISRLEKKFELGARFAMTQPLFSREAVERMMDKTSHLDMLIFPGIFPIISARN
AEFLHNEVPGMSVPAEFRRQLASYPEVPDQRKAALDYTRQLVEDIAPVVDGFYFVSPLNK
WDIALEFVRQVRQAGWQGSGRATP
>A0A842LVI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanomethylicales archaeon|TrEMBL
MKKAYSGFMRALSEGKFVFTGEVEPKKTTKLDGIIRAASVLKSHVVACNVTDNPRARAYL
SSLVASYVIQRETGLETICHMTVRDRNRLALTSDLLGASALGIRNVLVISGDHTMGGDNP
GAMPVYDLDSTQFVQMVRGMVDNGIDLNGNPIDGEVRLHVGVVGNPNADPLEVEVCKVER
KIKAGAEFIQTQIVFDVEKAKRFLKDLNPSIPVLIGIFPCKSYRVAEFIVNKIPGISVPK
EYIDGLKSAESPGSPSESKNKIDAVNMDYFSNFIKELKKTTKAAGIHIMTMGYESIVGKI
ADGVLDEARGLN
>A0A352V9I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetia bacterium|TrEMBL
MKIKDIYNKNKHIISCEVFPPKNDDDILKLYNTINEIKEISPDFVSVTYGAGGSTRDKTV
EIASHVKNIIGIEVMAHLTCVNSTVSDIDKTLDELKSRNIENVLALRGDPPQGQENFTKT
LGGFGFASELTRHISANHCFSIGVAAYPEGHIEAKDLATDIENLKIKVDSGADFMVTQLF
FDNSYFYKFRELCAKKGINIPMIPGILPILNYNSVKRITSLCGTIIPAKLKELLEKNQDN
KEEIEKIGIDYAIKQISDLLDNEIDGIHLYTMNKSNETKAIFNAVKEKIMR
>A0A6A3JM10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora fragariae|TrEMBL
MDPPQTLDTCDSRLLPNDSLATSVSAFIKWEEAAALEAFPLAVVPSNHPHTREKGSKMPR
VSSIHVTKQKERHEEADELAATKFVLDDSTVWTGLSTEDTRAAGESEGDQERLLQRLHLV
QGLLTFVRMLRRSRGLQAEEEDDEAKTSAQWTPEWASLKRALGLQRLKAKQDAGADFIIT
QFFFDVDNMIHWIADCKDAGITILPGYLSIQNYSSFCKFTSWCKTRVPESVLAALDTIKN
DDAAVRRYGTQLAAETCQRLLAAGVNSLHFYTMNLPRP
>A0A7L1W884|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Certhia brachydactyla|TrEMBL
MVNETQHTCSVSSSSRSDGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFQPQTFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A1X7R6Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kazachstania saulgeensis|TrEMBL
MKITDKLQKHHDVSPKATFSFEYFVPKTTQGVQNLYDRMDRMYQSSLPQFIDVTWNAGGQ
TSKLSQSSTELVSTAQSVLGLETCLHLTCTNMPVSDIDDALKEAYDSGCQNILALRGDPP
SNDYKWEPCKGGFLYAKDLVAYIRLKYGNHFDIGVAAYPEGHPEEKDSIKNLNYLKQKID
AGANFIITQMFYDVDNFINWCHNVRQFGIEVPIIPGIMPITTYSAFLRRCQWGSINIPLH
FSQSLEPIKDDDELVRAKGTDLVVEMCQKLLDSGYINHLHLYTMNLEKAPMMILELLDLL
PTEAEFINDPVSVLPWRKSLNPQRRNEEVRPIFWQRRPYSYVARTSQWTIDEFPNGRFGD
SSSPAFGDLDLVGYSLFRQSPQKALQLWSTPKTMQDISQLVINYLQGKLVCLPWSDTPLN
HEVDTLLTHLIMMNKNGIITINSQPRINGERSNDKIHGWGPKDGYVYQKQYLEFLLPREK
LSKLTEILKGNEIMTYFAIDFNDNLSTNHPDGSKANAVTWGIFPGREVLQPTIVEKVSFL
AWKEEFYRILEDWKSIFIKDNDNESIQLLNSLINDYVLVNIVDNDFVSTEDQIFTLLMTL
>A0A428DH06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLVIPTIAHLPAIYLTKDKVAETITDLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIREQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A2K8WT51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacterium sp. HL-69|TrEMBL
MGNNLSKLQGAIALKEFLITAEITPPKGGNPERMLTVAKVLKNRVHGVNITDGSRAVLRM
SSVAASALLLKEGIEPICQVTGRDRNSIGLQADLMGAYALGIRNILALTGDPIKAGDHTQ
ARAVFELESIKLLKLIDKLNLGFDINNKPLVDGNLDLFAGAAVDPQSKSWSGLQRRFEKK
LEAGAQFFQSQLITDFEKLDKFMTQIAVKGDRPILAGIFLLKSAKNALFINKYVPGVEIP
DHIIKRLEKAKNPLQEGIKIASEQVKMAQDICQGVHLMAVKKEELIPEILDLARIKPLQ
>A0A3R8TNN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Empedobacter falsenii|TrEMBL
MKVTEHIERANGKPLFSVEILPPLKGQDVNATFKTLDPLVELNPAFIDVTYHRQEYIYKQ
KENGLLKRYQVRKRPGTVAICAAIQNHYKIDAIPHLICGGFTKEDTEDALIDLNFLGIDN
LLVLRGDPIKSEKSFVPEVGGHANASELIEQITALNTGNYLDDELQESHAMDFCIGVAGY
PEKHFESPNLAMDLYYLKKKVELGADYIVTQMFFDNQKYFDFVKKCREMDINIPIIPGIK
PLTTFNQLTSIPQNFYLDLPEALAMEVLKSKDKERIKEIGIEWCIQQCKELIDFGVPGLH
FYTMSNSINTKRIAEAVY
>A0A0K0X1T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium goodii|TrEMBL
MTYGPCGGVRPDGQCEMRSGDCVFDDVVSWDGPLATPTPVGAPLVLTDFSCAPFDEADVV
RTADILAGSCDAVLVGEHQNKPDFPPTLMGRILLDALSESDVAPWITLSCRDRNRVVLEQ
ELRGLRSIGLNTVMCVTGDGRGYDVRPDVTQTFDLDGPRLVALAAALDMVAAVPETPTAP
PVPARPRRLVEKQKAGAGIAVLNHVPHPQTVARFAESARSEGLTIPVIAAVAVFTDSVSA
AVLQGLPGLELDPVVTERVLGAADPVESGIEAAVDEAHALLSIDGVEGVNLSGSASSSGT
RVGAEIKAEVGRRIKNLRIAKARGEAP
>R9AC58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia ichthyophaga (strain EXF-994 / CBS 113033)|TrEMBL
MSRSSALSCVFPPKTEQGFVNLKSRLQRLSLLNPGFISVTWGAGGSTDERSLELAATARS
LGLDVLLHLTCTNMHKTRIDSALDRAKQLGIDNILALRGDPPRGHEYWIETDAAFRHSSD
LVHYIRQRHGDSFCIGVAAYPECHKDSSSAAQDLNYLKLKQDLGADFIITQLFYDSDAFL
NWLDKCATNGIEIPIIPGIMPIQNVPSLRRLANLCGAHIPSVISDHLEPIKNDDALVKDY
GVELSTSMVRQLIDKTNSEKDKYRHLSLHATHFCTLNLEKSVRRILANLGWSAGLDSSSL
EPNGLTNKNSDALERARLGNRLVAENGSTGHDTSGAPPQLSITAHEAAVRALHALKHHPP
SEDSGLPSSNKTSSGGNSLWDEFPNGRYGDIRSPAYGELDGWGASLKTSSQNALRQWGYP
LQTSDINEIFKKYINGDISCLPWFEENLDPESNSIKDYLFKLAEKGWWTVGSQPAVDAIE
SSDAVFGFGPKNGWIFQKAFVEFWVPDHQLEPLCKRLDGWKDGGYYAGNAKGEMRSNFYE
DTINAVTWGIFPGQEVVQTTIIEDVSFNAWREEAFDIWLEWSMLYSPKSASQQLMKNVHD
NYWLVSVVHHDYKDTYGLWDFLLS
>A0A3B0WUY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKTQKKHKKHFSCEFFPPKTDKGMSKLLITADTLKTEMNPEFFSVTFGAGGSTRENTFNA
VTKIHQSTGCEVAPHLSCIGSSKQQLTEILDSYTQQGIKRIVTLRGDMPSGAVSHSDFNY
ANELISFIREHYNNHFHVEIAAYPECHPQSKNVTDDIKFFKQKVNAGANSAITQYFYNID
SYFYFIDNCEKAGLDLPIVPGIMPITNYSNLARFSNMCGAEIPKWLRQKLESYADDTDAI
KDFGCDFVSNMCQKLLDMGAPGLHFYSMNQTEATLHIWNNIKHSG
>A0A081K6U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endozoicomonas elysicola|TrEMBL
MANTIINNTPISFEFFPTKTEDGARKLELSALSLAKYQPEFFSVTYGAGGSTRDRTLETV
LSTQNQTLIATAPHLSCVGDSREQIKELLNFYRTQGVKRIVALRGDLPSGMGRDSGELRY
ANELVEFIRAETNDHFHIEVAAYPEVHPQAPNMEKDLENFKRKVDAGADSAITQYFFNAD
SYFYFLERTRAFGIDVPVIPGIMPITNYTRLARFSDACGAEIPRWIRKQLEAYGDDITSI
KKFGEEVVTQLCEKLLEGGAPGLHFYTLNQATPCQGICDNLGISVS
>F0RPU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus proteolyticus (strain ATCC 35074 / DSM 20540 / JCM 6276 / NBRC 101906 / NCIMB 13154 / VKM Ac-1939 / CCM 2703 / MRP)|TrEMBL
MTTTLYTPRISVELVPRTRESLQAELDELRRLWPAITAVNLPDLDHLELGSCESCALPQA
QGLSRIPHLRASRIALGDVPQVLRQLGSLGVSEVLVVQGDPPTDGRPVQSTTSLELIRAL
KAAQPDLTVHAALDPYRQSLQDEQTYALRKIEAGAASLFTQPLFDTRLMEVFGEMLPGVP
IYWGLTNVSSERSRNYWIRRNRAVFPASFEPTLDWCTDFAREAVQHAQSTGSHLYFMPIR
TSLRDFLGAVFPPAGGGVDPEGQELGAAALAAAGHHRRQAGAFS
>A0A4R7UI73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. CC22-02|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAADKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCNRLVALRGDLPSGMGFPGDMRYAAELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VQRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRRMQAYGDDVDSVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQL
>A0A1W9XB78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_88|TrEMBL
MKLKEALKTKRFVVTSEVQAPMGDDKPEELVENLKRVRGRVDGVSVTEVELEGIVGDSIK
TCEILKENRFDAIYQTTTRDKNRIQLQKDLTHAHEAGVENLLVFTEDYRITGDSLQETMF
FHVDSGKLASVLEHIREGQAIDGQELPFKADFVLGSGVESPWGQNVPKQGMQEMEAMQNM
GTGYFLTTPIFELDQFERFMKQVNTFGVPVIAEVMILRTAGMARFLNRHFKAGLVPERVI
QKLSNAPDKQQASIDIFTETVKGLKDLCQGIHIITIGGEEKLMKYLDAAKLR
>A0A7X1KBV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium aerophilum|TrEMBL
MVAPVIHPAWERPPLGITEGYSIEITARDVPALQEAAPAMPVDTPVAVTFLPGEAQPDRI
AAAVAVRELGFEPMPHFSARRLVSAEEFEEYLGAVVERAGVRRCFVVAGDPPEPQGPFAD
SMALIATGTFERNGIRAIGVGGHPEGHPVMSREECWQVLDTKVAEITARGMAPLVVTQFG
FDPDAVLGWLAEARARGIEAPVRIGVPGPAGIKRLIAFAARCGVGASTSVLKKYGISLGN
LLGSAGPDRLIEAFAAGLAVEHGRVRLHFYPFGGVGRTVEWIRAYDHGHGLIRPR
>A0A091ALN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp. F21|TrEMBL
MRENRFKEALLNPAEFPVTWELVPGRGAKEAAQEKALALASQAAAGNKILALTLTDNPGG
TPAMSADFMGCEILKLGIEPLVHFTCKDKNRNQSESQLYALDRAGVRNLLVMSGDYPVSG
FQGRPAPVFDLDPVHTLQLITDMNRGLTYPGIKGNVTHQPGDFFPGAVVSPFKATEAEQM
SQYYKLKKKIAAGAQFIVTQLGYDARKFHEVLLFMKQNGLNIPLVGNVYILPFGAAKMMN
RNDLPGSVVTDKLLADIDRERNDPDKGEGARILRSARLYAVLKGMGYSGVHIGGHNIRYE
QVEEIIRQGEALASGWTSLIRYFDYPIDGGFYYFERDPDTGLNLEAQTRLQDRPPDAEIE
CTYGFSRFFHQLMYEPGKNLYGVMKELCKKVQGSRVESFFHKLEHLTKVALFDCRDCGDC
ALIDTAYLCPMSQCPKNQRNGACGGSFQGWCEVYPGKRKCVYVRAYARLKKHGEQDQMGK
DIVPPCNWDLYQSSSWVNYYLGKDHTSKKQI
>A0A1F2T4H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium RIFCSPLOWO2_02_FULL_67_21|TrEMBL
MKPFLEAIDQRVLVCDGAMGTMLYAKGVFINHCFDALNITDPGRVAEVHQGYVRAGADVL
ETNTFGANRIKLRGFGLADRLRDINIEGVRLARSVAGRQAYVAGAMGPLGVRIEPWGKTG
RDEAEAFFREQAAALLAGGVDLFILETFRDLNELLAAIAAVRSVCALPVVAQMTIEEDGN
TLDGTPPEQFAPALEPHADVVGVNCSIGPAPMLETIERMAAVTRARLAAQPNAGRPRDIE
GRNIYLSSPEYVASYARRFISHGVRLVGGCCGTTPEHIGLISRAVRALAPEEARAAARDR
SSHHAAAHVSVAAADGSVPVVPRAGRSQLSHALAEGRFVTIVQLPLPKGHLSDAVLEQAG
ALKTLGVDVVLLRDGQGGARMSALSLAVLIQQKVHIETLLQYSCRDRNLLGMQSDLLGAH
AMGLRNVMLVTGDSRMVGDYPDATAVFDVDSIGLTNVVTRLNHGLDIGGQTIGSPTAFHI
GVQVNPGAEDLDNEVRRFEYKVAAGAEFAMTKPVFDAATFERFHRRVESSRLPLILGLWP
FESVLNAEFMANEVPGVRVPDAVLDRIRRAPTPEAEAAEGIAIAREVGAALKGIVQGVHV
AAPSGRVEAAVEVLQGIG
>A2RKK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris (strain MG1363)|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYLDKTQVIEILERLREKQTMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGADKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>A0A7S0TNW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hemiselmis andersenii|TrEMBL
AGVALVEIPLSERTGLSAKVARIWEGRLNGGMSKASPTGPEDFVVSVEVNPSPGLSTDKP
VSIAKMLREGGVDVVNIADGPRATVRMSNTALGEVIQRELSMETIIHVCCRDRNILGLMS
DLLGNYSRGLHNLVVITGDPPKMGDFPKATAVFDMDSVGLLKMIHGLNTGLDPAGNQFAG
QAKYFCATGAEPGAVDYEREIRRLKEKIAAGADMVMTQPVYDASVMRRFLDDVASFPKPV
PILLGLCPLVSSRNAEFLHNEVPGMSVPQNIRDRMASVGGGPAGVAEGVKIARELLEQFQ
DEVVGCYVMPQLGKYDAAIEVVRHLGYGADDSAMRRDAPVA
>A0A7X1F685|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium aerophilum|TrEMBL
MGKPLIHPNWDKQPEGITDGYSLEITAKDVVALREAAPLIPAETPVAVTSLPGEELSARI
AATVAVRELGFEPMPHFSARRILSREEFETYLDAVVRDAGVKRCFLVAGDPPEPQGPFFD
SSALIATGSFERNGITAIGIGGHPEGHPIMSAQECWDVLALKIADIESRGMAPLVVTQFG
FDADAFLGWLKQARQRGIDTPIRIGVPGPAGIKTLLRFAARCGVGASASVMAKYGLSITN
LLGSGGPDKLVDRFAASLGAEHGRVRLHFYPFGGLGKTVEWIGAYERKNGLA
>A0A1V5XY89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division BRC1 bacterium ADurb.Bin183|TrEMBL
MMKSFVESAHNRILVCDGAMGTMIYTSGVYINQCFENLNLSKPDLIEKIHKEYILAGADI
IETNTFGANRLKLTPHGLGEQTSDINAAGVKIAKKAAGKDVFVAGSIGPLGKLLEPMGPV
PPQEAQQIYIEQATALIENGVDLIILETFSHLPTLKIAVSGVRKVSSDIPILAQMTLSEN
LEIFTGEKPEQTVVELSALPVQAVGFNCSVGPADMLEAVRMARPATNLPLSAQPNAGAPQ
KVEGRCIYLATPEYMAEFAKRMIQTGVNIVGSCCGSTPAHTRAIRAAVRALVPSRIVEQV
RVEEKPEKAQARPELPSPSVFARKIAEKKFVVSVELDPPAGTDPAGIVESAKKLRKANVD
AVNIADGPRATARMNPTALALLIREDSGMETIVHYCCRDRNLLGMQSDLIGANALGLYNI
LIVTGDPPKMGDYPFATAVFDVDSIGLTKIARNLNTGLDLAGNPIKGQTSLFIGVGANPG
ALDIDEEVRRFEKKVENGARYALTQPVYEVRLLENFLKRIEPFRIPLLVGILPLSSYRNA
EFLHNEVPGMQIPEAIRERMRRADTKEAARMEGINIARESLREAKPMVDGVYIMPPFGRI
DAALQTLEI
>A0A0C4UTQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria bernieri|TrEMBL
AYGIHLGTEMCKKILAHGIKTLHLYTLNLEKSALAILANLGLIDMTKIKRHLPWRPPANV
>A0A8B6M2J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocella tundrae|TrEMBL
MSENASCDLPRASRTHQPDIRVSFEFFPPKTVAMEALLWESINRLAPLGPSFVSVTYGAG
GSTRERTHSTVARLAKEGVVKPAAHLTCVAAARKEIDSIVQGYWDAGVRHIVALRGDPQE
GVGTKYCPHPEGYESSCALVAGIKRIADFEVSVSAYPERHPESLSLEADLDFMRAKVDAG
ANRAITQFFFENEIYLRYRDRLQERGVDIPIVPGIMPMQNFKQTAGFARKAGASVPQWLA
DRFEGLDDDPQTRRLVAATVAAEQVLNLVDHGVRDFHFYTNNRADLVYAICHLLGLRPKL
EQKAA
>A0A5J4F2F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa NIES-4325|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAAFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLARQLCQGVHIMAIKREDLVPKILDAAGIPPIHN
>A0A3R6KS15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. AM59-24XD|TrEMBL
MKIADICKKKKSLSFEIFPPKRTEDLENIDETLSVLCECDPDFISVTFGAGGSSNCNRTI
ELAKKIKNEYHVEPVVHLTCLHYNKSEIDEFARILTQEGIQNVLALRGDRNPDIPEKDDF
KHASDLIRYLKPKSDFCFLGACYPECHPESDGKISEMKHLKAKVDAGAEVLLSQLFFDNE
QFFRFVEDCRIAGIGVPVIPGIMPVINARQIKRMVTMCGASFPERFQRILHKYEDNKEAL
FDAGMSYALSQIIDLLVSDIDGIHLYTMNNPLVARKICDGIRHII
>A0A2N6TIE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSLEEPDYISVTYGAGGNTKGRTV
EIADRIKRQNGLESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEKGD
FNYARELIEYIHKKKGDKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPEIAKKIIDATGIIRK
>J2KST3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium populi|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLVERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTPGGHASAMDLVHQINDLGRGKYLHNEDRECDELNKFCIGVAG
YPEKHIEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVQKAREMGITIPIIPGI
KPIATKKHLKILPQVFKIDLPEELISEVENAKNNEAVKQIGIEWAISQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>D1C8I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerobacter thermophilus (strain DSM 20745 / S 6022)|TrEMBL
MDNTWACRVLGDSRLEVLPTITAEKLAPLVPPSMKVTVTVSPDLGIDATLALTADLHRRG
VRVVPHLTARGIAGPSELERIIANLMELGIDEVFVIGGDPDRPVGEFESALDLLESLATL
PKRPSTIGIGAYPEGHPKISDDALMSALLAKQRYASYAIMQISFNPEAMLTWINEATAAG
FTLPLYLCLPGTIRFDRLVRIAMRLGIGASLRYLEKQRGLARFVLTGGARYDPWATIGEL
AESQDAARDRIIGVHWSTFNAVESTVKWVQEKQRELGCPGNGSA
>A0A2A4B4U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas spermidinifaciens|TrEMBL
MTLSVGQLEEARRALDGPLFADVAGDADVSFEFFPPKTDKMEAAMWEAVQTLAPLGPRFV
SVTYGAGGTTRDRTHGTVARIARETSVPAAAHLTCVEASRDEVDAVAREYWAAGVRHIVA
LRGDPPTLGDKFVPHPEGYASAADLVAGLKRLHPFEISVAAYPEAHPEAASASADIDNLK
RKLDAGATRALTQFFFEPETFFRFRDAAAAAGIGAEIVPGILPVSNFAQTQKFAGMCGAA
IPDWMGRLFDGLDAHPAARQLVAATIAGELCRRLYAGGVRHFHFYTLNRAELSYAICHLL
GLRPKAEETRAAA
>F4RGV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7)|TrEMBL
MKISQKLAAAEAEGRVSWSFEYFPPKTDNGVANLYDRIERMSQLGPIFIDITWGAGGTTS
NLTTEFVKTAHRQFGLETCMHLTCTNMPQEQIDSALKEAYDSGCENILALRGDPPRGSSE
WTATEGGFTHAVDLLRHIRSTYGDHFDIAVAGFPEGPTDPNLTRLQETMYLKEKIDAGAS
FIFTQMFYDVDVFIDWVRELRAAGIKVPVIPGIMPIQSWAQFKRITTFHKTAVPPSFLSQ
LEPIQNDDQAVREVGTRLIADMCRKILDSDLGIKILHFYTMNLERGTKMILDELEMSPYR
DITNPLPWRLSLSGKRRTESIRPIFWANRTKSYLTRTETWDEFPNGRWGDSRSPAYGELD
GYGININPATAESLKALSKPPTNLSQLASIFAAYCDPMRAQLSGAQIVKHLPWSDIPLSS
ETSDIADILAKINQRGFLTINSQPAVDGAKSSDPVHGWGPRGGYVYQKAYLEFFCSPEQF
NSLQRRLDNDPDVTYYAVTKTGQLKTNNQNAGPNAVTWGVFPGKEIIQPTIVELVSFLAW
KDEAFELGQQWAELYKSSLDEERLKSYKFIKSVMDNWFLVNIVNNDYRKSNSDCEIQSDS
ALFKFFKPEPIIVEVEEKTGTGVMTNAIKKIQDGVATLTVTGTTTA
>A0A1G3DAH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium RIFCSPHIGHO2_01_FULL_64_12|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKAELRELLNLYKSAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVQTPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A3B3XTX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poecilia mexicana|TrEMBL
MRKRMESGDQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETS
SMMIASTAVNYCGLESVLHLTCCNQTKEKITSYLAKAKHLGLKNIMALRGDPVGDDWEDE
EGGFNFAVDLVKHIRSEFDDYFDICVAGYPTGHPEAESYEQDLQHLKEKVDAGADFVITQ
LFFRADTFLKFLDDCRAVGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKIIEPIK
DNDAAIRNYGIHQAVDMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWVEDPRRPLP
WAVSANPKRKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYL
KSKSSKEALLQMWGEELKNEQSVFEVFTCYITAQPNRNGQKVLCLPWNDEPLAPETNFLK
DELEKVNRRGVLTINSQPNINGKPSGDPVVGWGPPGGYVFQKAYLEFFTSSENVTALLKV
LKKYEPRVNYHIVNVHGHNMTNAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAF
ALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWHVIDDMFELLDSTPE
PLTDEAGSQ
>A0A1H2RED9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinococcus luteus|TrEMBL
MNVLEKLDSSILIGDGAMGTYLYQKGYKGSFEAMNLTDPEAVEHAHREYAEAGADILQTN
TYAANRVKLEGYGLEDKVQDINRAGVQLAGNASGGSAYVFATVGGIKGVQVSEYSDDFLR
NALEEQVDVLLAEPVDGLLLETFYDLPELLQIIRYIRSKDAEIPVIAQVALGDVGVMHGG
VQISEAFSRLEDAGASVVGLNCRMGPYHILKSLEQAELTDRAYYSAYPNASLPNWYDGRY
VYQSNPEYFYKQAFRFKEQGIRLIGGCCGTTPEHVRMIAEAVKHDVPEKTKRPVKVEAPA
AEATADKEAFVPLHEKVKNEKTVIVELDPPKKLKTGKFIRGSQALHDAGADAVTLADNSL
ASPRIDNLAMGAMLRQQTSARPLLHIACRDRNLIGLQSHLLGLHTIGVRDLLAITGDPSK
VGDFPGAKSVYDANSVSLISLIREMNEGRLFSGKSLGQKTNFSIGGAFNPNVLHIDKAVK
RLEKKVNAGAHYFMSQPVYDIERIKTIHEAVKELGAPVFIGIMPLVSAGNAEFLHNEVPG
IQLTGDTRKRMAACGNDSEAAKREGIAIAKELIDETLRYFNGIYLITPFLRYEITAELTK
YVREQASAGVKEI
>A0A368F994|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancylostoma caninum|TrEMBL
MNYNIVGYPLGHPESPSYKADLLYLKSKCDAGAQFIVTQLFFEAEVFEQFVRDCREMGIT
VPIIPGIMPIMGYDSIRRIATLSQLTIPESILSDLEPIKHDDDAVRKYGTIKAIEMCRRI
LSNGSAPSIHLYTMNREGACR
>A0A4V1V269|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loktanella sp. IMCC34160|TrEMBL
MTRPKVSFEFFPPKSLDASFRLWDCVHALSPLEPEFVSVTYGAGGTTRTLTHEAVGTIHK
ATGLTVAGHLTCVDASRAETLEIAESYAAAGVTEIVALRGDPPKGAGGFRANPDGFGSSV
ELIEALAETGKFTIRVGAYPEKHPESADAKADIDWLKRKIDAGATSAITQFFFEAETFFR
FRDACVKAGIDAPIIPGILPIENWEGARRFAKSCGTSIPQVVEDAFTNATRDGTTELLAT
ALATELCDDLLQGGVDHLHFYTLNRPELTRDVCHALGISPRVRLQQVA
>A0A1I0J4Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter actinosclerus|TrEMBL
MKVTEHLSRAEGKTLFSFEVLPPKKGENIQTLFSNIEPLLEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFVPEPDGHSYACDLIGQISDLNKGEYLDQEQDDTWATGFCIGTAGY
PEKHFESPNYGADLRYLKHKVDRGAEYIVTQMFFDNEQFFAFERRCRQAGITVPIIPGLK
PLTTKSQLTMLPRSFYLNLPEELADAVHLAPDNAAARQIGLEWCINQSRELMAHGVPCLH
YYSMGKSDSIRQVAAALF
>A0A2N6CMV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MAGSTAVQSGSALGAVSDNPVNVSFEFFPPASEKMEATLWQSIQHLAPLGPTFVSVTYGA
DGSTRDRTHRVVSRLLRETDLTAAPHLTCIGASRDDIKAVARDYWDLGVRHIVALRGDPP
QDQPAYRPRRDGYAYAVDLVRGLREVADFDISVAAYPETHPEAPDSASDIDNLKRKLDAG
ASRAITQFFFDTGLYLRFRDRCAAAGIDVPIVPGILPITRFPQLQRFAKACGASVPQWLE
AEFEGLEDDRDTRRMIAANVAIHQVRQLQR
>A0A2E9JWQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
MADTDRLQVSFEFFPPNTPAMETTLWNSIQRLAPLRPRFVSVTYGADGSTRDRTHRIVSR
IGAETGLRAAPHLTCVGSTAAEIQAVARRYWDEGIRDIVALRGDPPADAEKYEPHPDGYE
YGVDLVVGLREVAEFEISVAAYPEVHPEAPSAAFDMDCLKRKLDAGATRAITQFFFDVDN
FLRFRDQCIACGISASIVPGILPIGKFPQLLRFAKMCGASVPQWLHERFEGLDDDAETRQ
MISANIAIEAAERMRAEGINEFHFYTLNRAEQTYAICHALGIRPQNDPPDDG
>A0A497X5I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoreibacter meonggei|TrEMBL
MTRPNVSFEFFPPKSVEASFRLWDTIQTLAPLDPTFVSVTYGASGTTRELTHEAVTALHK
ATDLRVAAHLTCVDATREETLAIARDYIKSGVTDIVALRGDAPKGQDFTATDNGFASSIE
LIEALKTETDATIRVGAYPDSHPEAGSMDANIAYLKRKFDAGADAAITQFFFEADTFFRF
RDACVKAGIDKPILPGIFPIEDWTRASNFAKRCGTHVPAWLEEAFATAIRDDRHDLLAQS
VVTELCSDLVDGGVDHLHFYTLNRPELTRDICAALGVTQKVALAQVA
>A0A4T1ZZG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus aeridis|TrEMBL
MPAAPTRPAVSFEFFPPKSLDQSFRLWDTARALAPLGPDFVSVTYGAGGTTRQLTHEAVV
ALSNHYHLNVAAHLTCVDATREETMQIVEDYASAGVQEIVALRGDAPQGQAQFTPHPLGF
ADSVELIEAIAARGGFTIRCGAYPEPHPDSPDGAADVAWLKRKVDAGATSAITQFFFDAD
TFFRFRDACAKAGIAAPIIPGILPIQSWTGAKRFAARCGTSVPQWAEDAFVAAGKAGERA
LATDLAAGLCRTLIEGGVDRLHFYTLNRPDLVADVCAAIGVRAPDGAEQAVA
>A0A2A3B4G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3866|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARYEVDAVIQEFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A8H6NR18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum plurivorum|TrEMBL
MHIKAMLEESRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMFHFGPKFIDITWGAGGRIA
ELTCDMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRRAYKAGCTNILALRGDPPREKEK
WEATDDGFQYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDGDNFIRWVGKVRERGIDVPIIPGIMPIATYASFLRRAKHMNCKVPEEWMTAL
EPYKNDDVAVREIGKGLVADMCRKIIAAGIHHLHFYTMNLAQATRMVLEELDWMPSSERP
LKHALPWKQSLGFGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSIKDVANIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSSHPVHGWGPPNGYVYQKAYLELLVHPDVYPEIVARIEKNP
DMTYYATTKNGALKYNSSNDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGTDW
AHCFEAGSPSRVLIDRIMNEWYLVNIVNNDFHQKTALFDLLDGLAAKEYDDIPSEPQQAN
GASKSEVPNGNSASATAN
>A0A7W5X3X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. BK481|TrEMBL
MTTITIPQLAEARRALEEPLFADLAGDVGISFEFFPPKSDKMDAQLWDAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLARLHPFEISVAAYPECHPESGGHDVDLDNL
KRKLDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFANACGA
EIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPSEKVAAA
>A0A7K1VM39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. VKM Ac-2803|TrEMBL
MSTSRAESPPEPHCPASVPFSFEIYPPRTEAGTTALLRTVDRLAAARPSFISVTYGAGGS
SRRASLEILRYLRRSTSIEALAHLTCVGSTHAEASRLVHEFLEAGVTRFLALRGDPPVGS
PEGADVLGDLGSAAELVQLIHRVQAEREPYGAVAVPGLPNAQRVDVAGRPRAQVAVAAFP
NGHPRSRSRAQDIDALLAKEAAGASFAITQLFFHPADYVRFVERARAAGVRMPIIPGVMP
VTSPARLRRMLELSGEDLPAELAIALDVEPDDDARRRIGVAHAASMVRTLVEAGAPAIHL
YAFNRHEEALAVLAESGLLPREPAPAGGPHPSPSLTTERAS
>A0A7X0IG71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerisporangium rubeum|TrEMBL
MASGRPSVLPGRVPTVRELLAAGDRSFSFEFFPPKTDTGERLLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVEIVERLAHETTLTPVAHFTAVDHSLRELRHLIGRFAGAGVRNILAVR
GDPPGADPLAEWVAHPEGVHYAEDLVRLIRQAGEFCVGVAAFPYRHPRSPSVESDTDYFI
RKCRAGADYAITQMFFRAEDYLRLRDRVAAKGCDTPIIPGIMPVTQMSTIERSEKLSGAP
FPPEVAARFEAVADDPAAVRDLGIEHAAELCQTLLDEGAPGIHFITFNKSSATREVYQAL
APSRPTANAV
>A0A7Z9WNH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bipolaricaulota bacterium|TrEMBL
MKLRELFREGRFVVTSEVGPPKGTDVKEMLENAELLKPRVDALNITDQQSSVMRLGSLTA
AHLLKERGVEPIYQLTCRDRNRIALQSDLLSAWALGIENILCLTGDYVSLGDHPGAKPVF
DLDSVSLLATAKRLNEGYDLAGNELAGRPDFCLGAVVTPGANPLEIQLIKMEKKVEAGAE
FFQTQAVYEPERFAQFMEEAKELKVPIIAGIILLKSAGMARFMNKNVAGVYVPEHLISEM
ERAKDRVAKSIELAARLIREIKDLCQGVHIMPIGWERHVPAVLEEAGLASGL
>A0A6N1Y9X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|methanotrophic endosymbiont of Bathymodiolus puteoserpentis|TrEMBL
MMTKKNKADLFSFEFYPPKTEEGAVNLEKVHQELAQLNPDFFSVTFGAGGSTRDKTYDTV
VKIQKNGVSAAPHLSCVASTKENILEILQNYRQHGVSKIVALRGDLPSGMMSAGEFRYAN
ELVEFIRKETGDHFQIHVAGYPEIHPQASCAQTDFDNFKRKVDAGANAVITQYFYNAEAY
FYFLDKCEKSGIDIPIVPGIMPITNYSQLFRFSDMCGADIPRWMRKTLEGFGDDRESIVA
FGEDVVSKLCQELLDNGAPGLHFYTMNQAKPTLAVWNNLKF
>F2A1M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium etli CNPAF512|TrEMBL
MALKNEAQARNIGISFEFFPPKSEEMEGQLWNTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRRAGISIPIVPGIMPIQNLTQLKRFAGACGAVIPGFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIRDFHLYTMNRSPLVSAVLDNLGLSRRPAKNAGAAA
>A0A2G3LHS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. BJB426|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVKRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A1H7GRQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius azorensis|TrEMBL
MGTPRISFEFFPPKTLEASFRLWDTIHTLAPLDPRFVSVTYGAGGTTRELTREAVGTLHK
ATGLNVAAHLTCVDASRAETLAIAEQFAAAGVTEIVALRGDPPKGTGGFTPHPEGFADSC
ELIAALAETGKFTIRVGAYPEKHPEAADSRADIDWLKRKIDAGASEAITQFFFEAETFFR
FRDACAAAGISAPIIPGVLPIENWTGARKFALACGAQVPAWLDDAFDKAMRDNRHDLLAT
ALATELCSELIEGGAEDLHFYTLNRPDLTRDVCHALGVMPRVTLRDVA
>A0A4Z0L8D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium humi|TrEMBL
MKVTQHIENAQGKSLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPNGLLQKKIVKKRPGTVGICAGIQNKYQVDAIPHILCGGFTKEDTENLLIDLDFLDIDN
VVALRGDALKNETYFKPEKEGNQNATELVSQIHNLNQGIYLDEDLQNSSCTNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGADYIITQMFFDNKKFFDFVAKCRKAGITVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMEVVKAKDNEAVKQIGIEWCTEQSKELVAAGIPVLH
YYSMGKAENIKAIAKQVF
>A0A1T4M4I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carboxydocella sporoproducens DSM 16521|TrEMBL
MLQQKLAQGRQVLTVELPPPRGIAFQEVLELALAIKEKVTAYNITDNQRAVMRMSPVAMA
ALLLQAGLEPICQFTCRDRNRLALQSEILGAAALGVRNFLLLTGDHTLVGDCPGAKPVFD
LDSVQLLAAADNLRRGFALNGEPLQGVPDLFLGAVVNPAPELREMQIWKLQKKIRAGAAF
VQTQAIYDPGILADFLQEAGELGVPILAGVIPLRSARMAHFMNANIPGIQVPPAMIRALE
KATDPLAEGLAITVELIRELRTLVPGIHIMPVNTLRALPTLLARLEGEEHEG
>A0A3S9CJW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1E.F.Ca.ET.045.02.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDDMEARLWDTVTRLEPLKPQFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIREFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHSFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAVCHMIGIRSHEADVA
GSAAA
>X2H2B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snodgrassella alvi wkB2|TrEMBL
MSFTQLSFEFFPPRTEEGRRKLAITRKQLSQYQPEYFSCTYGAGGTTRAGTLQTITDIMN
DGVAAAPHLACIGASREEMISLLQTYKDMGIRHIVALRGDVPSGVGFGHQGLRYANELVA
LIRQEFGDWFHIEIAAYPEFHPQSRSAEDDINHFVRKCQAGADSAITQYFFNADSYFWFV
DEVQGRGIDIPIIPGIMPIASFSKLARFSETCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCDHLLQQGAPSLHFYTLNQAGLVSTICQRLGY
>A0A1G5D3D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium XPB1003|TrEMBL
MKVSEIYKSGKRSLSFEIFPPKKEEELRDIDDTLDVLCELKPDFISVTFGAGGSSNCNRT
IELARKIKDKYKVEPVVHLTCLCYDKKEIDEFARVLNDSGIENILALRGDDREDIPRKTD
FMHASDMAAYLKEKNDFCILGACYPEKHPESEDLISEIHNLKKKTSAGTEVLLSQLFFDN
KIFYDFKEKCRIADINTPIIPGIMPVVKATQIKRMVALCNASFPERFQKIVDLYADRKEA
LFDAGMSYALSQIIDLIASGTDGIHLYTMNNPCIARRICEGIKNII
>A0A4R3KFE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidibacillus fermentans|TrEMBL
MSTYQIHGLKEKLTLGKFVVTVELEPPKGANPMPVLEKAAFLKGYVDGVNIADSPMATLR
MSPIALAHVIQQDMGIEAIFHLTCRDRNVIGLQSELLGAAALGVRNILTLTGDQPTRGDH
PDARGVYEVDSIGLAKIAKQLNEGLDLTGHPLNGPTQFFIGAAANPGADDLDVELEKLKR
KVDAGVHFVQTQPVFDLNQVERYLELTRDLPIHIIFGILPLKNGKMAHYLNQKVPGIQIS
EEIISKVEQGGREAGIEVGKQLIEKIKGIVQGIHIYPIGDLTMVSELLDIPQKMPKVI
>A0A2I1Z315|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia mucilaginosa|TrEMBL
MTTVHPALSFELFPPRSHASCESLLHTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSARLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSDAE
LHRIGVEYALNQCRTVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEY
A
>A0A381SZ67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MDLNPTPIFSIEFYPPRTNADESKLNAVHQQLAKLRPDFFSVTYGAGGSTKQGTKQIVLR
YQKFGSSMAPHLSFSGTDQDEIRILLAAYKAAGINRLVALRGDSPSDGSAITHHRYASEL
VEFIRLETGEYFHIDVACYPEPHPDSKTYESGVGYFKEKIDAGANSAITQYFYNADAYFY
FVEYCYKAGISIPIVPGIMPITNYANLARFSAKCGAEIPYWLQKRLEGFGNDVAGLREFG
IEVVTVMCERLLAGGAPGLHFYSMNLAKSVTQIWTNLALSDRH
>A0A383B240|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
FPPKDEAAADRMLRAAEDLRPYEPDFVSITYGAGGGTRETTMRYARALKEDLGFEVMPHL
TCVGHTKEELLEILGEFRDAGFRAVMALRGDPPKGEDSFSAVEGGFSHADELVSLARAHF
PEFSIGVAGYPEKHPEAPDFGSDVTHLANKVSCGADFVTTQLFFDNAKYFSFVDSCRTGG
IEVPVLPGLLPVGSLSQIKRFCAMCGATLPDELTRRLEAAGDDPSVVGQVGADWAYGQLA
ELLDGGAP
>A0A829SBP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 225588|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGEHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A7W2HUP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseoaurantiacus|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTVSSFEFWAPKTEKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRSGTVRATERIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMAEWVAHPEGLTYAAELVHLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVD
KCRAGADYAITQMFFEPEAYLRLRDRVAAAHCETPVIPEVMPVTSVKMLERLPQLSNAVF
PRELKDRILAAQGDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHTRQA
>A0A0S6XDL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fungal sp. (strain No.11243)|TrEMBL
MERISDKIAALPQHGSYFSLEFFPPKTQQGFANLHARLSRMSHSLRPLFVNVTWGAGGST
SEKSLALVELTQRQLGLTTCLHLTCTNMSRRLIDETLEYAKTLGVRNILALRGDPPRSDE
YRAENGNEDEKDDSNKDFTWAVDLVRYIRKQYGDFFCIGVAGYPEGHADQSHPEHQSVDF
DLPYLVEKVQAGADFIMTQLFYDVEAFDKYEDLLRRHESSAFRTIPIIPGLMPVQSYQIL
KRTTKLSHAKCPQPILSRFEAVKGDDEAVKRVGVDVISEMVQHIKSRRQSRPRGFHFYTL
NLEKSVAQILERCELIAPPTPPMVTIDESAVDDDEGDGYLLVNSSKTQGRSRRVSQEANN
RVIRDRSRAMSSSSALFEASEDEVSGPPDSKQPSRLTVLAISEGEGSLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHVSIPAALGLWGRPSSTGDLTAIFERYVLGEIDAVPWSEE
ALNEETNTIRDELVTLIRKGWWTVASQPAVNCTLSTDKIFGWGPKNGFVYQKAFVEMFLP
AKDWKRLQPLLDDDDQLTYFAADATGAYAASDEDSVNPVTWGAFRGKEIVTPTIIEGMSF
KAWAEEAFGIWKEWGVVYKPSSESHKLLRSTREDVWLVNVIHHAYVEPQALWEFLAKA
>A0A8J6ZYI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desmonostoc muscorum LEGE 12446|TrEMBL
MHHTHSPTAFRRAVQAGEFLVTAEVAPPKGGDPAHMIKMAATLKGRVHAVNITDGSRAVL
RMSSLVASVILLQNGVEPICQFACRDRNRIGLQADLMGAHALGIHNILALTGDTVKAGDH
PDAKAVFDLEAVRLLQVIRKLNQGVDCNEKPLTDGALDLFAGAAVDPQSKSWSGLQSRFE
RKIEAGAQFFQSQLITDFERLEKFMDTIAAGYKKPILAGIFLLKSAKNAQFINKCVPGVN
IPQHIIDRLAKAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIAPILDLAGVAPI
NQLVSR
>A0A382W6I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MTKNFRSFSFEFFPPKTPQGKKKIKAIAKKLEFFSPEYFSVTFGAGGSTKQGTIETCISI
ASNSTEACPHLSGIGSSKEMIKQILNKYKSNGFKRIVALRGDLPSGIGGTGDFPYAVDLI
EFI
>A0A8H7IUS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ascochyta lentis|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMDRALVDEALEQAKVLGIRNILALRGDAPRSEE
YRDEDKTPEQDSNKDFTWAIDLVKYIRQQYGDYFCVGVAAYPEGHSDESHPEHQNPSYDI
PHLVEKTQAGADFIMTQLFYDVDKYEKFETMLREHESGAFKTIPIIPGLMPIQSYSILRR
TTKLSHANLPADLLARLDAVKADDELVKKVGVKILGEMVEHIRSRPDVVRRGFHFYTLNL
EKAVSHILEDTHLIGRIPTEDDEDVIETTPAINLEPPNGIPSNRQRRRLSSINSSPHNRV
IRERLSASKSNQSFETYDTEAGQPRGPVNTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSNTSALKLWGHPVAQDDISDLFKRHVEGTLEALPWSEQTLSE
ETSTIAPQLLALIAKGWWTVASQPAVNGVRSTDPVFGWGPKNGYVFQKPFVEFFVPSAAF
NELKPRLDAHEQITYFAGNAAGDFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFKSWR
DEAFSIWKEWQRIYPTKSATGKLLRETRNDVWLVNVIWGDYVEGDGLWEFLGA
>A0A8C7ZAM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzias sinensis|TrEMBL
MVNQRVDGGWQACRSDSSGGSNSSGESSKDSSRCSTPLPDSDRGDRLRDKMRRRTESGDR
WFSLEFFPPRTASGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVN
YCGLESVLHLTCCNQTREKITGYLAKAKHLGLKNIMALRGDLISVNQLVVSRWTCPFVLQ
GYQSLRQLVKLSKLEVPEDITKVIEPIKDNDAAIRNYGIHLAVEMCSILLESGNVPGLHF
YTLNREVATMEVLRQLGLWLEDPRRPLPWAVSANPKRKVEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEELKNEQSVFEVFTCYIT
AQPNQSGHKVMCLPWNDDPLAPETNFLKDQLEKVNRRGVLTINSQPNINGKPSTDPIVGW
GPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHEQNLTNAADMRPNAVT
WGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVN
LVDNDFPLENCLWQVIDDMFELLDAPPELLGTETT
>A0A841BD27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis umgeniensis|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTLRTLHTSIKLSGAPAPRRLLDRLEPLA
DDPKSFRAAGIDAVTELCERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A2D7HTZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MTYSQINVSFEFFPPKNEDSIASLWNNIKRLEPLKPRFISVTYGAGGSTRENTHSLVKEI
KEKTSLNPAAHLTCIGTSKSEIERIADEYWSSGIKHIVALRGDERENGHGSVKDFKYATD
LIKVLKDRFDFEITVSAYPEMHPDSKSMDQEYDVLKKKIDLGASKAITQFFFDIDCYFEF
VDGALKRGIKIPIIPGILPVTNCKRTFEFAKKMNCKMPKSLIEMFDGLDSDPETRKLVAT
TVVHDQCKKLLEGKVNDFHFYTLNRADLSFAICHILGIRS
>A0A258YDP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium 24-39-8|TrEMBL
MKVIDHISQAKDTLVSFEVLPPLKGKTINTLYDHLDPLMEFKPSWINVTYHRSETMFKKK
TDGTFERVEVRKRPGTVGICAAIMNHYQVDAVPHIICGGFTKRETEDALIDLDFLGIDNV
LVLRGDAAKNESAFEPEKDGNHFAIDLLSQVSNMNNGIYQDEDIKSGGKTKFCMGVAGYP
EKHFEAPNLEIDLIKLKEKVDAGADYIMTQMFFDNQKFFDFVTACKNMGINVPIIPGLKP
ITNKKQLSVLPRIFHVDIPTDLSNAINKCKTDAECEQVGTEWLIQQSKELKAFGSPVLHY
YTLGKPKVIWNVVKNVF
>T0ISP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium ummariense RL-3|TrEMBL
MTLTFPSVEEARRALDAPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIGTLTPLAPKFV
SVTYGAGGSTRERTHNTVARIARETPLSAAAHLTCVAASRDEIGEVADAYWEAGVRHIVA
LRGDPPEQGKSFEPHPQGYAGAAELVEGLMKRHPFEISVAAYPETHPEAASPQSDLDNLK
RKLDAGATRAITQFFFEPDTFFRFRDKVAAAGIDADIIPGIMPVSNFAAVQRMSAMCNTD
VPGWMGKLFEGLDDLPGARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPKVADVAA
>A0A523Y3R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium|TrEMBL
MKAGSNLEKVLQSGQFAVTAELGPPKGSDAEVVKKKGNLLRHCADAINITDNQTAIARMS
SIACGVILTQLNLEPVIQMVCRDRNRLAIQSDILGAAALGIKNVLCLSGDHQKFGNHPQA
KNVYDIDVIHLIQTLKKMRDEKKLLEGDELTIEPRLYIGAVENPYADPYEFRVIRLAKKI
KAGCDFVQTQGVFDVKKFKDWMRVITDQGLDRKVHILAGIIPVKSAGMVRYMRDYVSGIS
IPEEIVARMENAKDARREGVNICLEIIEQLKEIPGLHGIHIMAVAWETIVPIIMNEAGLV
PRPVA
>A0A3M0ZM83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MGASRAELDRILDRLEAAGVENVIALRGDPPRDATHFEPAPDGLAHAVDLVRLIRSRGRR
LCVAVAGYPEGHVEAPDLDTDVGFLAEKVAAGADLVITQLFFENRFYFDFVERARARGVK
VPIVPGIMPITNLAQIERFTTMCGATIPPALHRVLEWAGDEPERVVQIGIDHATEQCMEL
LERGAPGIHFYTLNKSRSTYEILRRIRERYPGTGG
>A0A1G6LY91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinokineospora iranica|TrEMBL
MKTVVERIRTGRPVFSVEFMPPRDEADEQLLWNAIRELECLDPAFVSITYGAGGSSRDRT
IRTTGRVARETTLVSMAHLTAVDHSIAELRNVIGWYAALGVKNILALRGDPPGDPNGEWV
PHPQGVNYADELVRLVRELGDFCVGVAAFPYGHPRSPDLDFDTDNLIRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAARGHETHLLPGVMPLTTPKILAKTVELSGAQVPPRIAARLDPLV
DDPEAFRAEGIDLVTEMSQRLLAEGVPGVHFYTFNRSKATKEVVGRLGLVPSRA
>A0A1Y3WUL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. An54|TrEMBL
MNVVDIIREAIATKRTRFAFELLPPLKGDGSQKIFAAIEPLMPYRPAYINITFHREAIKE
TVREDGSIEWHVVRRRPGTVGISAAIQQRYGVEVVPHLICGGLSKYDIEDTLIDMDFLGL
HNVLALRGDKSQNERRFMPHPQGHAHAIDLVRQIDDMNHGRFIDGEVEECHHSKFSIGVA
GYPEVHFEARDITSDIAHLKAKIDAGAEYVITQLFFDNRKYFDFVRRCREAGITVPIIPG
LKPLSTPRHLEVLPETFHVSIPEELAREVKAHPESAREIGTEWAIAQSRKLMAAGVPVLH
YYTMSRTTNIQKIVSALF
>A0A4Q1B851|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tremella mesenterica|TrEMBL
MKITEKLQKAEREGRTFWSFEFFPPRTAQGLQNLFDRIERMRNLGPEFIDITWSVLGAGG
KNADLTSNLVQTCQEQLGLECCMHLCCTEMPKEKVEWALAQAKAHGCQNILALRGDPVAG
SSTWKPTPGGFHNAVDLVRYIHSQYPGDFCVAVAGFPQGHPETADTPESRHQEMVWLKQK
VDAGGDFIFTQMFYDTDIFFDWVKRVRAAGIDVPIIPGIMPIQNWEKFQTWVKREKIVVP
PHFYDQLLPIQGDDEKVRQVGTKLVADMCRTILANEEAGIKGLHIYTLNLEKGAKMLLTE
LGLEGGREQIAPLPWRPSLTPHRRTESIRPIFWANRVQSYLSRTDDWDEFPNGRWGDSRS
PAYGDLDGYPVAIGISSTEAYSLWGHPTTFDDICRLFTRFCRGELAKLPWSSQPPSSEMT
TIADRLAKMNELGYLTINSQPGVDGVRSEDKVHGWGPAGGYVYQKAYLEFFVSPALLSPL
IRRIERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDE
AFELGCQWAALFPEDSPSRRLINDIMNTSYLVNIVANDFKDGASIFEPFLLDQPNGSLNG
VKQTASTIVDRVSGLFDGH
>A0A658NSD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. AAK_AS5|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGCGKPDMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A3M1ZL60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MSDADSRSNLERVLTSGGFAVTAELGPPKGADPEVIRRKADLLRGVADAVNITDNQTAVV
RMSSIAAALLARQAGVEPVVQMTCRDRNRLAIQADLLGAWALGLRNLLCLSGDHQTFGNH
PGAKNVWDIDSIQLLKIMADMGERGVFANGEEVEGAPPRFFLGAAENPFAEPYPYRPFRV
AKKVKAGARFIQTQCIYNMARFREFMARLGDLGLLDKVYVLAGLSPLKGPGMAKYMRDQV
PGMDVPDEIVERMVAAGQGIDDKAERSKAFRAEGIRICIEQIQQVREIPGVAGVHIMAIE
WEEAVRPIVEGAGLLPRPQPLPDAAHAGG
>Q2G3D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199)|TrEMBL
MNASYDQLREARTALDTPLFAGLPGDIAVSFEFFPPKSDALMAQLWDVVETLAPLQPTFV
SVTYGAGGSTRDRTHGTVARIIKEAKLPAAAHLTCVDASKAEIREVAESYWEAGVRHIVA
LRGDMGAPGVPFTPHPDGYANAAELVAGLKQIAPFEISVAAYPESHPDSPDQQADIDNLK
RKLDAGATRAISQFFFEPETFFRFRDKLAAAGIDAPVLPGILPVSNVAQTRKFAAACGAA
IPAWMDGLFEGLDTHPASRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPRTPALEKAA
>A0A2E5J679|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MFVGLDSDPETRKLVAATISAEQCKKLAKEGVKEFHFYTLNRADLSFAICHILGIRSLKE
LKIDD
>A0A2D6ZXU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MIFLELVPKDMEQLLKDVKDYLTDFSAIDGVNIPDIKRISNRSYNVTTELLKHNINAIPH
IRTRDDEMTVHLNRIEALVESGLDKILLVSGDIHQDAIHQVTPLLLTKELKKRFNGLKVY
TALDPYRHSFKDEVQYAKEKIEAGSDGFFTQPFFEKELCEQYINQFKNVDIFIGISPVMT
QKSYDYWVRVNNVTFPQSFELSQSYNAKLAKELLSVSKRYNKSSYIMPISIKVDDYLKSI
FLD
>A0A7X4BIG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0662_bin_26|TrEMBL
MHIAEVFRQSQPAISFEFFPPKSEAASESLFHTIQKLIPLKPAYVSVTYGAGGSTRELTH
DLVVKLHNETNLTIVSHLTCVKSRRDEIFKILQRYDEHGIQNIMALRGDPPTQEPWDPAE
QDFHHAVELVAFIKEHFPHMGIGVAGFPEGHPDTPNRLQEIEHLKAKIDAGADYICTQLF
FDNRDFYDFCERCRLAGIRVPIIAGIMPITSLKGMKRMAELALGARFPGRLLRALASAKD
DAQAEKIGTHWATEQVLDLLDNKVLGVHLYTLNRSRASLQIYETLGLQRVDMPME
>A0A7J7ISC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bugula neritina|TrEMBL
MSTRGIPSEIFDPPTPPHSTDCSRSQSPFSVLNKFKPLRQKVLDRYESKDPFFSFEFFPP
RTANGALNLLSRMERMSQGGPLFCDITWHASGNALSSEPTSSLTFAMAMINHIGLNTMLH
ITACKQQVEDIDRHLNKAKDLGVSSLLLLRGDPPQGHEWDPNAQCFGYASDFVKYVRETQ
GDNFTIAVAGYPMGHPDGESYADDLLHLKVKVDAGADFIITQLFFDAETFIKFVRDCREI
GIECPILPGILPIQVNSYVMSKTVCLKCLWCCFYF
>A0A1H4BPA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oribacterium sp. KHPX15|TrEMBL
MRIIDILNNGETTLSFEVFPPKKIENFDTVQQATEEVAALKPSFMSVTYGAGGGTSEFTL
NIAKTIRDKHGVEVLPHLTCVSSTKEHVHNMLSKFKEYGFENIMALRGDIPKDGTPHHDY
HYASELIADIKAHGDFCIGGACYPEGHVECIHKDEDIKNLKKKVDAGVDFLTTQMFFDNA
EFFNFLYRLRENDIRVPVLAGIMPITNAKQLGRSVALSGTSVPTRFREIVDKFGDHPEAM
KQAGIIYATEQIIDLIANDVKHIHVYSMNKPDIAEAIQKNLSEILKI
>A0A3A9KD25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacteraceae bacterium SP2|TrEMBL
MYNNFKSKLKGGQFTVTVEISSPKGTYLNQILQDIRELKDVVDAVNICDNPMANMRMGSI
PLAHIIQETLGIETIPHMACRDRNIIGIQSELLGAWALGIKNIFAVTGDAPAKGDHPGAA
GIFEVDSKGLIKIIDTLNNGRDLANNTLKGSTEFFIGTAANPAAESLDGEIIKLEEKVLS
GANFIQTQPVYDMDVLDRFLEKALLLDVPILVGIMPLKSQRMAINFNSRVEGVNIPLKII
DRMKRGRREGIEISWELAEEIRERGCGVHLMPLGDIEDAVQIIKGLRLADKKVQDASGTL
>A0A257L7Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium B1(2017)|TrEMBL
MKVTEHIKNAKETLFSIEILPPLKGKDINSIYNGINPLMEFKPAFIDVTYHREEFVLRKR
KDGGFDKVYTRKRPGTVAICAALMNKYHVDTVPHLICGGFSKEETENALIDLHFLGIDNV
LVLRGDNIKNEPNFVPEPDGNKDSLELLKQVVAMNNGKYLDEELENASNSNFCIGVSGYP
EKHFEAPNLQSDLRWLKQKVDSGAEYIVTQMFFNNAKYFEFVDTCKKMGIEIPIIPGLKP
LTTKRQLTILPKIFNIDIPEDLVHAIENCKDDKAVKQVGIEWAIQQSKELKAAHVPVLHY
YTMGVAEVTKAIASQVF
>A0A1D9FLY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium formicaceticum|TrEMBL
MSLLRNAIEKGEFAVTAEMAPPKGTDFHHLMECARAIKGRVHGVNVTDFQSAVMRATSLA
TCKLLKDEGLEPVLQMTGRDRNRIAIQGEFLSAAVFGIPNVLALTGDHTVVGDHPQAKPV
YDLDSVGILQAATTLMGGKDMVGNDIEGGLDFLLGACVTPRFDPVEAQILKMEKKVKAGA
RFFQTQAVFDLDTMREFREKTKHINAKVLAGIIPLKSAPMAKFMNNNVPGIYVPDELIER
MKNTEKDLRVQEGIKIAGEFIRQLREENLCDGVHIMAIGAEENVPAILDAAGL
>A0A147J4B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sanguinis|TrEMBL
MTNTILTRAEAALAHEEPLFADVGGDIAVSFEFFPPKTEKMDTQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTLAAAAHLTCVEATREEIDQVAQEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPESTDKAADLDNLK
RKIDAGATRAITQFFFSPEAYFRFRDDAAAAGITAEILPGIL
>A0A2J0KUJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG07_land_8_20_14_0_80_50_8|TrEMBL
MNILEIYHKKKFVITAELGPPKGTNLRPFFRQAGYLKGRVDAVNVTDQQSALMKLGSLAC
CHLLKDFGLEPVMQITCRDKNRLALQSEILSGSVLGIRNVLVLTGDPIAIGDHPQAKCVF
DLDAAELMAVIKTMESGVDMTGHPLDGVPQFSIGAALNPCAEDMEIEISKIRNKIKKGAD
FFQTQGVFDVERFKKFADRYQKEGFRAPLLAGIILLKSPKMANFMNEKIPGVHIPGALIA
RLEKAEDPKARSVAMACETIQSIRSCIQGVHLMAIGWEELIPEIVSKTS
>A0A2N2UJ18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-13|TrEMBL
MNNTELSIEFFPPQTEEGAEKLRAVRARLAELKPSFFSVTYGAGGSTRERTFATVKEIAA
SGCEAAPHLSCIGSTRDSIRAILAEYAEAGIKRIVALRGDLPSGVGDAGEFRYANELVEF
IRAETGQRFRIEIAAYPEWHPQARSPRDDLLAFKRKAEAGADSAITQYFYNIDAYLHFVD
AVRGMGVDIPIIPGIMPIASFSKLARFSDACGTEIPRWMRKKFEAFGDDSESIRAFGLDV
VTAMCEKLIASGAPGLHFYSMNQSALTTEICQRLKLA
>A0A836WAU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MSRLQKSLERGEFVVTGEIGPPKGINVEATLKEASYLRGRVVAVNVTDNQSSVMRLGSLG
VCVRLLQEGYEPIFQVTCRDRNRLALQSDILSAYVLGIRNVLALTGDHPALGDHPGSKPV
FDLDSVSLLMAIRSLMEGKDLAGEELDGKPSDLFPGATVTPGADPLEPQLIKMEKKIEAG
AKFFQTQAVYDPKVFENFMNQASKFEVPVLAGIVLIKSPAMARYMNENVPGVFVPDSIVK
PLSEVSRKDRPKKSIELMAGLIKELRPLCQGVHIMAMGWERYVPELLDACELQAPM
>A0A6I4G386|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium vitis|TrEMBL
MAHTSSNRDQARPFKLSFEFFPPKSEEMEAQLWATVDELTGWEPEFVSVTYGAGGTTKAP
TLAAVRRLLAETPLATASHLTCVGATREEIAQVVEDFRAVGVKHFVALRGDPPTGVGSAY
QPHPGGFENAAALVKGLKELGDFEISVSAYPEKHPESADLAMDLDMLKRKVDNGATRALT
QFFFDNDIFERYLDKVRAAGINIPIVPGIMPILNLTQLKRFAGMCGTSVPAMLDQRFEGL
DDKPTERASVAAALAAEQIADLQGRGIDEFHIYTMNRAPLVNATLERLGLQRSDTVAASR
AGVVA
>A0A7W1E535|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
MSDRKALLDRLLDPFQVVVFDGAMGTQLYAKGVFINQCYDELNLRAPDLIREVHRAYIKA
GAEVIETNTFGASRAKLEQYGLQSQVSEINREAAKLAREVAEDDVLVAGAVGPLGIRLEP
YGPTSLLEARQMFAEQMNGLKKGGADLFILETFADLHEIEQAILAAREIAPDFPIIAQMT
IGSDCLTPYGVSPEDIAKSLDAFGADIIGLNCSVGPQTILDAIEKMSPATRRKLSAQPNA
GMPREVSGRSMYMASPEYMATYAHHLVQAGVKIVGGCCGTTPEHIASIVEGIRPLVPRQR
KTVQDRRVHHAEIPDEPKGVAPVPFADRSRFSAKIARGDFVTSVEIVPPRGVDATRMLKD
TAALKAAGVDAVNVPDGPRAQSRMGALLTSLLIEQRVGIETVTHYCCRDRNLLGMLSDLL
GAAATGLHNILLITGDPPKMGPYPNATAVFDIDAIGLTNLVSNLNRGLDPGGNPIGAPTQ
FAIGVGVNPAAIDPANELSRFEWKVDAGAEYAITQPVFDAEQLERFLGTINHTRIPIIAG
IWPLVSLRNAEFLANEVPGVTVPQPIIERMRRASAKSKEAGVAEGIAIAKEMLERVRPLV
QGVQVSAPFGKVELALEVFGDHIKAEAATE
>A0A831UMP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus islandicus|TrEMBL
PQLRRFTEVCGASIPGPLLSRLERHQDDPQAILEIGVEHAARQVAELLEAGVEGVHFYTL
NKSPATRMVLERLGFKPA
>A0A847CSZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierellia bacterium|TrEMBL
MTNKNKFKFPLLFDGGMGTYYPVKSPKALPECEMANLFDAQTILEIHKEYVNAGAKAIKT
NTFQANKRALTAEFDVVERVIKAGIQLAREAVKGTDAVVFGNIGQIGADEFTHFEEYKEI
IDVFLEEGIEDFLIETFSSLDSIPNMAKYIKEKAPNAFVITSFSISSDGQTRYGEIGENL
LQEAAECEAIDAIGFNCVSGPLHLREYLEKIDIPEKLISVMPNAGYPTVINGRTFYSNDK
DYFANATLRLLDTGVNIIGGCCGTTPEFIKVISEKLGEYHVPREPRKKAKELRLENPYAE
NLFRNKLENGMRPIAVEYDPPQDLDMGKYIENVKRLDKAGADAITIADCPVARVRVDASF
TAYKIKNEVGIDPIVHMTCRDRNINATKALLLGLNIENILNVILITGDPIPTAERDEVKS
VFQFNSTKLAGFVEDMNENTFTNKINIGGALNVNARNFDIELQRAKKKEEAGVNVFYTQP
VISHQAAENMKKARAELKGYIMGGLMPVVSHRNAVFMDAEISGINVEQEVIDRYEGVDKE
TADKLAVEIATYFGEKIKDHIDGYYIITPFNRVDLVTEVIKNLEK
>A0A7W1C2W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
MADESKLARLLDPLQVVVFDGAMGTQLYAKGVFINQCYDELNLRAPDLVRDVHRLYVDAG
AEVIETNTFGANRIKLSQFGLGGQVGEINEAAAKIAAAAGEGDVLVAGAVGPLGVRLEPY
GPTSLDEARAAFTEQMRGLVAGGVDLFLLETFADVHEIEQAILAARAVDRDMPIIAQMTI
GTDCLTPYGVSAEDVAKTLDAFGADIIGLNCSVGPQTILDAIEKMAPVTRRKLSAQPNAG
MPREVSGRSMYMASPEYMATYALHLVHAGARIVGGCCGTTPEHIAAMVEGIRPLSPRTAM
ASSVERRKQRPDAPEEAVGVDPVPFAERSKFAAKIARGEFVTSVEIVPPRGVDASRMIRD
CRSLKEAGVDAVNVPDGPRAQSRMGAVLTSLLIEQQVGIETVVHYCCRDRNLLGMLSDLL
GAAAVGLRNILIITGDPPKMGPYPNATAVFDIDAIGLTNLVARLNRGLDPGGNAIGAPTS
YAVGVGVNPAALDIPHEIKRFEWKVEAGAEYAITQPVFDVDQLESFMKKIEHVRIPIIAG
IWPLVSVRNAEFLANEVPGVSVPDHIIGRMRRAGEVSKEAGVAEGIAIAREMLDRVRPIV
QGAQVSAPFGKVELALEVFRSLAWAEAVP
>A0A6P4WY32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panthera pardus|TrEMBL
MDHPTPKVLLARPRCPSLRMWALEANSGRFSVPPSIRNPAMVNEPRGDGGPTSRSEGSSS
GSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRFD
RMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCCQSREQITGY
LHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDVCVAGYPKGH
PDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQG
YHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHFY
TLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQEW
DEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMWGEELTGEESVFEVFACYLSG
EPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGWG
PSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTW
GIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNL
VDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>A0A1Q7QJB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium 13_1_40CM_3_65_7|TrEMBL
MRNVLVLRGDPPQMGDYPNATAVSDVKPSGLVRLIKKFNQGHDVAGNAIGAPTGFTVGVA
LNLAAPDLDREARILERKMAAGADFICTMPIYEPEALDRFERIMGGLPRPALIGVLPLVS
HRHAEFLHNELPGFAVPSWVRERMRLAADGRQEGMGVAHELMEAVRSRVGGVYLIPSFGR
YDGVLELVRLARQPAKT
>A0A1Y4E733|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. An268|TrEMBL
MRIDSLFAAARAAGTIPVSFEMFPPKGELTLERARAAAEKLCALKPDFVSVTCSAGGSGN
SSATADIAQMISRDFGTSSVAHLTGIGLTHAGLAERIAAYRAAGVENVLALRGDLPQTGD
APSGDFSYAADIIPALVDAGFCVGAAAYPEGHIACDSLAESVRHLKLKQDAGASFLVTQL
FFDNDLFYRFRELADAAGITVPITCGIMPFMSKQQVTRMVFMCGASLPSPVIKLLARFED
DPDGLMRAGIDYACDQLVDLAEHGVDGLHVYAMNRPSVARAAMQALRAIGPL
>A0A5C5NXY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas rhodesiae|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAAQLASYQPDFFSCTYGAGGSTRDRTINTVLQLE
SQVNIPAAPHLSCVGDSKADLRGLLTQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANSGANSAITQYFFNADSYFY
FVERVRALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EHVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2H6AV68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR39|TrEMBL
MDLTGDLRRIVEGLRIERAPHRPFRVSVELFPPRTPEAKARFWPEVERLAGLRPHFFSVT
CGAGGTGRDGTYPTVLEIRERTGLPVAAHLTCAAHGREEVDALARAYWEAGVRHIVALRG
DPPKGSGPYVPRPDGYAYAADLVRGLRGIAPFEISVAGYPETHPEAPSRAFDIDNVRRKV
EAGAVRVIGQYCFDTDTVLRYRDELVRAGVEVPFVPGIMPVHDFAKIRRFSEACRASIPD
WLAELFTDLDPSLPVHGMVAAAVAAEQMSRLVAEGFDHLHLYALNRADLTLAACRLAGYR
PPAAAATETSSGRSACAA
>A0A1Y2W9M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypoxylon sp. CI-4A|TrEMBL
MHINQMLAEAEKTGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDITWGAGGRIA
ELTLDMVVQAQAYFGLETCMHLTCTDMGEEKINDALKRAYQAGCTNILALRGDPPREKEK
WVAADGGFQYARDLVSHIRRTYGNHFDIGVAGYPEGSDDNKDEESLLDHLKEKVDMGATF
IVTQMFYDADNFVRWVGKVRERGITIPIVPGIMPIATYASFLRRASHMKCKIPDEWMAAL
EPIKNDDHAVREVGKTLVAELCRKIMSAGIVHLHFYTMNLAQATRMVLEELDWMPSTTRP
RKQALPWKKSLALGRREEDVRPIFWRNRNKSYISRTQDWDEFPNGRWGDSRSPAFGELDA
YGVGLTGTNDSNRKKWGEPSSVQDVASLFIKYMERKLDSLPWSEAPLTSESDSLKDDLIE
LNKRGFLTINSQPAVDGVKSTHPVYGWGPSNGYVYQKAYLELLVSPDLYPEVIRRIEANP
DLSYYAVTQSGKLSSNAPSEGPNAVTWGVFPGKEIVQPTIVENISFLAWKDEAFRLGMDW
AHCHDANTPSRVLIEKLMKEWYLVNIVNNDFREPRAIFKIFDGLVVKDIDVPVAAPVQES
GVNGQSNGVHKEINVIPTTNGTSAVATA
>A0A4Y4F308|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas halmophila|TrEMBL
MSAQQHPMGISFEFFPPNTEAGRDKLMQARDALAARDPRFFSVTFGAGGSTQHRTLDAVK
AVRECGIDTAPHLSCIGSEKAQLRDLLTRFREDGIKRIVALRGDLPSGMGGVGDLRYANE
LVEFIREETGDHFEVAVAAYPESHPQAPSLDRDLENFARKMQAGADIAITQYFFTADAYF
HFVERARALGVEAPIVPGVMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSASIAAF
GEDVISRLSERLLDGGAPGLHFYTLNQAEPTLKVLDNLRF
>A0A6B1K5A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID5464|TrEMBL
MALGTASIRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPRGLAYAAELVELIKASGDFCVGVAAFPAMHPRSTDWDSDVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDRVSAAGCDTPIIPEVMPIASVRSLERIGSLTNAAF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHRPQA
>A0A3N2H7N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis thermoflava|TrEMBL
MAHVFLSALEENTVTGSFLENSSALAHRIGELVAAAAYEVIPLKGADQKVLEVPRATPLT
ITCSPKFGLRRTLEHVASASAQGFRVVPHLAARMVKDEKALRSFVSTVVGLGVDELFVIG
GDAEEPVGEFTSACEVLESLARFDHGLRRIGVGCYPEGHPKIDEAELIRVLRDKQESAHY
MVSQLCFDAASLTRWIDTIRSADVRLPLRIGLAAPIKTARLLELSMKIGVGQSVRYLQKQ
HGMMRSLLLGRSYAPERLLSAMGGHLTEPAAGIEGLHMFTFNQLDVTVEWQRRLAARLGA
>A0A7W4J5A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconacetobacter johannae|TrEMBL
MPFPLTAVRPLSHVPALGPVEVSFEFFPPKSTKMEDGLRQTVGALAPLGPRFLSVTYGAG
GSTRDRTLATIAALAHDTSVPVAAHLTCVDATRGQVDDVARAYWAAGIRHIVALRGDPTT
PGSRFVPHPDGYENAAALVAGLRRIAPFEISVAAYPETHPDAASPQADLDNLKAKIDAGA
TRAITQFFFEAETFLRFRDRAAAAGIDAEILPGILPVANIAQAYKFADMCGARVPDWMRR
LFDGLDDQPATRALVTTATAAELCRQLRAGGVSRFHFYTLNRAEACQALCRLLVNPQ
>A0A7W0LIB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MRIDEILRERRPVFSFEFFPPKTDAGEENLRATLEALRHDHPEFVSVTYGALGSTRDRTI
DIVKWIKQELGIEAMAHFTCVGATVDELRETLDEIEAAGVDNVLALRGDPPAGEEEWRQT
DGGLLYSTELIELLTGNYGFAVGAAAFPEVHPQAESPDSDIRFLKAKQDAGASFLITQLF
YDNEFYFDFVERARSAGVTVPIIPGIMPVTSFRNIKRITELCESKIPESLERELEAREED
EAAVHDLGIAYATLQCMDLLARGAPGVHFYTLNRSPATRAILAALRAAQPWTRAAQPI
>A0A7W6KFK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Martelella radicis|TrEMBL
MSESNETRGRKRDIHFSFEFFPPKSAEAEASWWRSVEELSTYDPGFVSVTYGAGATSQAP
TYAAVKRLVDETQLQTASHLTVVKASKGEVDDVIRRFRDAGIRRFVALRGDPPGGIGTAY
SPHPGGYANAAALVSALKAIDQDFDISVSAYPEKHPESADRTADIAMLKAKADNGADRAL
TQFFFDNDVFEDYLNDVRRAGIDIPVVPGIMPIQNLAQLKRFAAMCGADVPAFVERRFEG
LDDDPDGRFEAAADLAAEQVEDLIARGLADFHFYTMNRSKLMIAVLKRLGISPDAAICDA
EPCRLRA
>A0A7V3T0Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MKICEMFKNKKPVISFEIFPPKPDAPLESIFDSLAQFKSLKPDYISVTYGAGGSQRGRTI
DIASRIKNEYGIETMAHFTCVGHSVEEIDEMLNSLEDNGLENILALRGDPPENQPDFDFG
KNTYKHAYQLVRHIRNRNGFCIAGAAYLEGHIDSMRLKEDLQHLKEKVDEGVDFLVTQLF
FDNRLFFNFLDMAAALNIKCPVTPGIMPVFRADQIKTICAKSGCSIPARLVLMMDKYSDS
PDDLRKAGIEFAGLQIRDLIDNGAHGIHLYTMNRPKSTREILETAGLHN
>A0A7V6WHM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MRNRFKESLLDKDSFSVTWELVPGRGAREIPQEAAVAAAEQAAQGKRIHALTITDNPGGN
PAMLADYLGLEIFQKGIEPLVHFTCKDKNRNQMESQLYALDRAGVRNLLVMTGDYPVTGF
KGR
>A0A231RSH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella sp. CIP 111063|TrEMBL
MKPDLRTALARKPLVGDGAMATYLYQLGLPVGVSFEEFNLLKPDVIADVHRQYAAAGAQI
IETNTYSAQQNKLARYGLEKKVEEINAAGVALARKAVGDGVYVVGSIGAVRGGAGKNIRT
AIVKRDFEEQIGVLLSSGVDGLLLETFFDLEELSLALTLIRKKSDISVICQFAVEDPERT
HDGIPLAEAFRRLKGEGADVIGFNCRSGPTGILRALETIPADLSLPLSVFPNAGIPDYVD
GKVVYSATPEYFGASALRFADAGAKLIGGCCGTTPEHIAEIAKALQGYLPAEQSAAPAPA
ESPAVIVEAAPAPVEPPTHDAEPSIVDLVRERHTIIVELDPPRDLDITKFMAGAQALKDA
KADALTMADNSLAVTRMSNLALAALLKERVGIKPLAHIACRDRNLIGTQSHMMGFDALGI
DHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKAKFVVGAAF
NPNVKHLDKAVQRLERKISAGADYIMTQPVYDPELIVQIAESTKHLTVPIFLGIFPLASG
RNAEYLHNEVPGIQLSDSVRQRMSGLEGAAGRAEGVKIAEELLDVAMAHFNGIYLMTPFM
AYEMTVSLTEYVRSKSPSLNRNPAN
>A0A1M7CI12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter psychrotolerans DSM 18569|TrEMBL
MKVTEHLTRADGKTLFSFEVLPPKKGENIQNLFSNIEPLMEFKPPFIDVTYHREEYVYRQ
HPNGLLEKKTVRKRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGSFIPDPDGHAYACDLIGQVADLNKGAYLDEKQDDTWATDFCIGTAGY
PEKHFESPNYGADLRYLKHKVDRGADYIVTQMFFDNEQFFNFEKRCREAGITVPIIPGLK
PLTTKSQLTMLPRAFYLNIPEELADAVHLAPDNAAAREIGIEWCINQSRELMAHGVPVLH
YYSMGKSESIRRVAAALF
>A0A1U7DSK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Seonamhaeicola sp. S2-3|TrEMBL
MKVTDHIKNANGKTLFSFEVIPPKKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYID
KGNGLLDKRITRMRPGTVGICASIMHKYNVDAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VMALRGDSMKDEPYFKPCEGGHAFASELVGQIAKLNRGQYLHDDVEVESNSDFCIGVAGY
PEKHMEAPSLQTDLKRLKAKVDAGADYVVTQMFFDNQKYFEFVKKAREIGINVPIIPGIK
PIAVKRHLQLLPQVFKIDLPEDLIDAVEACKDNKAVRQVGIEFAIQQSKELLDFGVPVLH
YYSMGKSDNIKAVASALF
>A0A4P6RI27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. A1C1|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPKELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A4V3JP07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira perdikensis|TrEMBL
MNKILLELVPRDLETILNEANYVKDNCSQISGINIPDLLRFETRSWNAAAKVKSIFPNVI
PHIRAIDFDIDNCDQIIQSLSENQISSVVVIKGDPPTDMSKKVYPTTSIKMIKKLKKEIS
SLKVYAAVDQYRVGIKDEFDYIEMKKDAGADGFLTQPFFDLRLIDIFSEKLKGMDVYIGI
SPVITDKSQSYWESRNRAYFPKDFKPTMDWNIGYAKKVIQYCSQNELNLYLMPIRINLEG
YLKDLFE
>A0A1V6CQQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.Bin123|TrEMBL
MKVTDALGLTDSTMLSFELLPPLKGNDASRIYRTIENLLEFNPRFINITTHRDEIEFRER
PDGTIERRVVRKRPGTVAIAASIQHKYGIPVVPHIVCGGFTRSETEHVLIDLHFLGINNV
LALRGDGLKGEQIFRPETDGNAHASDLVSQISNLRKGIYLDPELKNTTPLDFCIGVAGYP
EKHAEAPNMESDLLFLKKKVDAGADFIVTQMFFDNKVYFDFVKKCRETGITVPVIPGIKP
IALMNQLTVLPKIFSINLPTALSKALSQSRTDADARRVGTEWAIHQAKELIAARVPGLHI
YTYGISDNVKEIAKAVF
>A0A2W4W5U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MLRQTNNSVNEKTMMNISFEFFPAKTDEGAEKLRATREKLSERKPEFFSVTFGAGGTTQD
GTLSTVLEIKAAGEEAAPHLSCVGSSKEKVAALLKQYKEHGIKRIVALRGDLPSGMLETG
SFRYASELVEFIRQETGDHFFIEVAAYPETHPQAKSPAADVDAFVHKVNCGANSAITQYF
FNLDAFLYFRDQVQHRISIPLIPGIMPVTNFSQLARFSDACGAEIPRWMRNRLQHFGDDR
ESIRAFGLEVVSNLCEQLIREGAPGLHFYTMNNAQPTLSILDQIGY
>A0A3S1VN06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.05.1.1|TrEMBL
MNDMRQELIQTRGSATFAFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLATAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLEICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWLRVNER
>A0A521YKQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MSFPASATDLGLHARLVELVTAGSLEISPRELHRAPQVAALLPADTCVYIPSLPRLPLAR
TLQAVASVREAGLDPVPHVSARRIRDRDEFREFLKKAVAEYGVHRVLVIGGDEPRALGPY
TDSVQILEEGILSECGVREFGVGGYPEGHPRIPRPALEAALRRKVEIAGEQRLGIYMVTQ
FSFAQPRVIDFCAVLARSMPDLPIYVGIAGPTDAVALARYAQRCGVSVSLRALRNLGTGI
AKLVTQTDPRNQVMAIARYARNREPSNVAGVHIYSFGGAERTAAWMRELIA
>A0A0A3XUI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium japonicum|TrEMBL
MTDLTTPARAEGQDGHLQNGHLSSKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFV
SVTYGAGGSTRERTHSTIARILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVG
LRGDPAGGIGTPYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDT
LKAKVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRAG
TSVPDWLAEKFDGLDDDAETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAISH
LLGIRAKSAQKAA
>A0A537DYW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MASNLLTRLQSGDFVVTAEITPPVSTDPAEFISRALPLKGLATAVNVTDGAGARVHLSSL
AAAHFLVQNGIEPIFQMTCRDRNRLALQGDLLGAVSLGIRNVLCLAGDDPKLGDQPEAKA
VFDLDSRGLLAMAHRMRAEQRLPSGTQVKGGVKLVLGAADMPIDPPPHWEPKALRAKLEA
GADFVQTQFCMDVAVARRYAKRLLDHGVAQRLPILIGVAPIPSAHSARWMREKLYGTLIT
DAQVARLEKARDPKAEGNRICIEVLQQLAEIPGVAGAHVMAPQNFTEIPVVIAESGVTGK
KRCLT
>A0A3P0RX14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Bp9004|TrEMBL
MKSIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAATATRTICERLAM
>A0A4R0GRL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kosakonia quasisacchari|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCAATGIDVEIVPGILPVSNFKQAKKFADMTNVRIPAWMSQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A355E7R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MAKRRAVKPTPEFGSEAEEERDRDDPAAQVAAGVEYAIRQYRGLIGSGVPGLHIYLFNKA
EATRRILATLNLPRYPHASGALIFTARSAWSRRISVRSETVWHCPLA
>A0A3B9YIU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MRIPALFSRGEPVFSFEFFQPKNPEDLAAFQATVRKLKDLSPAFVTITYGAAGTAREGTF
ETAAWIKREAGIETAAHLTCISHTRSEIERIVESFRRLGIENVVALRGDHPKEGPLLPPE
RRELPYAADLVRFIRARGDFSIAVAGYPEKHPEAPSMEEDLRRLQEKVEAGAEWVITQLF
FDNAHYLDFVARARALGVRVPIVPGIMPITSYAQTRKFTQMCGTAIPERILADLAPIAAD
REKVVAYGIDYAFRQCRELLDRGAPGIHFYTLNRSHSTTAILSRLRDSC
>A0A0G9MX16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantiacibacter luteus|TrEMBL
MTPPDYPAQAAHFANQPLFAGLPGDVTVSFEVFPSKTEKAEDSMLRAVHSLATLGPSFVS
VTYGAGGSTRERSLATATRIAREVHVPVAAHLTCVGASRDQTLAMADKFWDEGITRVVAL
RGDMPNEAGKLDHPFEAHPEGYSCAAELVEGLLERHPFDVSVSAYPEMHPEAKCADEELA
YLKRKLDAGANRAITQFFFSSDAFLRFRDRAVAIGIDKPIVPGILPVHNLSRTKQMADQC
GATLPDWIVELFDGLDDHPQARELVSATVNAEFSRRLYAEGVREFHFYTLNKSELAYATC
HLLGLRPVRENLLEQAA
>A0A5A7MRW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Iodidimonas gelatinilytica|TrEMBL
MSQLRSLSPSLFADRLADTDVSFEFFPPKSEAMETRLWAAIKTLEPLAPRFVSVTYGAGG
STRERTHNTVRRLIRETTLAPAAHLTCVDASREEIDTIVRDYRDSGVRHIVALRGDAPDP
SKGYQPTPGGYANAAELVAGIRAIGDFEISVAAYPECHPESASLVADLDNLKRKVDAGAT
RAITQFFFEADQYFRYLDHVRSYGIDVEITPGILPVTNVKQLKRFADGCGASVPRWMADL
FEGLDDLPQTRALVAATVAAEMCRRLQAGGVNSFHFYTLNRDELTYAICHMLGIRSSTHG
TSQEKAG
>A0A2W5D114|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium urealyticum|TrEMBL
MSTMISFMSASNPHGHHEKASPLPGAPPQPTLQVPVSEAIRGYSPGKIPFSVEFMPPRDD
AAQTRLWNAAEAFHDLGVSFASITYGAGGSTRERTMEVAQQLAAKPLTTLMHLTLVDHSA
DELRAMLQDYARRGMTNVLALRGDPPGDPLGTWQPTPGGLNYASDLIELIRNTPECENFD
IGIASFPEGHYRAEDLEQDTQVTLHKLRLGADYSITQMFFDVENYLRLRDRLAAADPIHG
AKPVIPGLMPITSIRSVRRQMELAGGEVPVKILERLEKAAAGDEVANRDAVREVGIDITT
EMSERLIAEGAPNLHFMTMNNVRATQDVLHNLGMAPAWGPGYGQDMVR
>A0A848NAG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium aquaticum|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICASIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHGSAMELVHQINDLGRGKYLHNQDEICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEDLINEVENAKNNEAVKQIGIEWAIAQCRELLEFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A5N6TM75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus avenaceus|TrEMBL
MHIQEKLAQNEAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKAGCTNILALRGDPPREKEK
WEAAEGGFRYARDLVKYIREKYGNHFDIGVAGYPEGADDNPDVDLLIDHLKEKVDAGGSF
IVTQMFYDTDNFIKWVNKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKSHIPEDWMEAL
EPVKNDDAAVKEIGKVLIADMCRRLIAAGIKHLHFYTMNLAQATQLVLEELKLMPSEETP
LQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSVKDLSHIFVRYLQGELSRLPWSDTAITTEANAIKDKLVE
LNGRGLLTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLVPPYLLDELIARMESNE
DLTYYAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHEASSPSRKLIQGVVDNWYLVNIVNNDFHNTTNLFELFKGLDVKDFDVEVTADKTDSQ
PQENGAEAVKN
>A0A1U7HQN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroogloeocystis siderophila 5.2 s.c.1|TrEMBL
MIAVNRLKTLLNAGYFVVSAELTPPRHYKIKPLISKAEKIADYVDVVHLNDNALSQARLS
NVVAAHLIQQIGIEPVVQLTLRHKNRIALQSDLLGLAALGIRNVMILGGYPCSIGSDPEA
KEANDISAIDAIAAIHNLTTYGKMFNGDAIAPAPDFYIGTIALPYATPDKLDESMALLEA
KIARGARYIQLQATFDLTAMQQWMAEVVKRGLHQRVHFIGAVFPFSSWKGLEFLQKMPGF
YIPNEVVERIRRGDCKSESLKITLELIEGMQAIEGIRGIHLRLIGSSDCSQIVQLAGLRQ
FA
>U5RT18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium autoethanogenum DSM 10061|TrEMBL
MSLLKEAFEKGEFAITAEMAPPKGTDLSHLIECAKKIKGRVQGVNVTDFQSATLKATSLA
TCKVLKDAGLEPVFQITGRDRNRIAIQGELLSAGVFGIENVLALTGDYTATGDHPGAKPV
YDLDSVGILQVASILNGGKDMGGTDLKGKPDFFLGACVTPRYDPLELQVIKMKKKIKAGA
KFFQTQAVYDMETLKKFKEETKAQGVDAKVMVGIIPLKSAGMAKYMNKNVPGIFVPDELI
DRMKNAEDKVQEGIKIAGEFIKAVKESGLCDGVHIMAIGAEENVPLILDEAGL
>A0A261G6H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium aquikefiri|TrEMBL
MFSLEVFPPRRTAPVGTIYDTLDGLQGMHPDFISVTYGTGKQADRTATARIANTIRTEYG
IPAVAHLTARYADKTTIDHELDLFEDAGVKATLALRGDSQLGTDPCGEFQYASDLVRYIR
ERKPEMTVYAACYPECHPEAPNLDVDIDNLKTKVDAGANHLISQLFFDNEDYLKFLDKVR
AAGITVPIEAGIMPVTNASRVKHMVGMCGSRIPSTVEHMIERWGEDPSAMQEAGIIYASA
QISDLVARGVDGIHLYTMNKAVTTRRIWNNVRSLFA
>A0A3E0DZR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus antarcticus|TrEMBL
MKITEHLGNAQNTLFSFEILPPLKGQSLKELLEGIAPLMDFKPPFVDVTYHREEFIYKKH
PNGLLQKISTKKRPGTVGICAAMMNRFHVDAVPHILCGGFTKEETENALIDLNFIGVENV
LALRGDAPKTEGKFIPEAEGHGFASELVEQIVKMNQGRYLHEETEIGFQTDFCVGVAGYP
EKHYEAPSLKFDLKHLKEKVDKGAEYIVTQMFFDNQKYFEFADQVRAAGITIPIIPGIKP
ISTLGQITMLPRTFFLDLPDPLMDELEKCKTNAEVKDVGIEWSIQQCKELVKKKVPSLHF
YTMSKADTTYKIAKEIF
>A0A0H2MKZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax paradoxus|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPEFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVRRLVALRGDLPSGYGIGGEFLYASDLVAFI
REETGRDFHIEVACYPEVHPQARSPEADLQAFATKVKAGADSAITQYFFSPEAYFRFVDD
VRKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDVV
TDLCARLQGGGAPALHFYTMNQSAATLAVLERLG
>A0A0Q3HN86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium aquaticum|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICASIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMELVHQINDLGRGKYLHNQDEICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEDLINEVENAKNNEAVKQIGIEWAIAQCRELLEFGVPVL
HFYSMGKSDNIKKVAGALF
>A0A2X2M509|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCQKHITLAIQIKLNVSIVHILKPVLMSFKP
ILMVQILKS
>A0A1Q3N4C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium 47-18|TrEMBL
MKITEQIAQATRTLISFEVLPPVRGTNISSLYSQLDPLMEFNPSCINVTYHRAEKTFKHL
PDGSYKSIEVRKRPGTVGICAAVMNKYKVDAVPHLICGGFTREETENALIDLHYLGVDNV
LALRGDAPKNERFFTPEEKGNRNAYELVQQVSNLNKGHYLEEETLNESTTNFCIGVAGYP
EKHCEAANMDLDLHYLKQKVDAGAGYITTQMFFDNKKYFDFVDKCREVGITVPIIPGLKP
ITTLSQLQVLPSIFNIDIPGELTRSLLQCRSKEDVGIVGKEWLVMQCRELMQAKVPFLHF
YTMGKNLVVRDVLKTIL
>A0A522UIX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MTKAGKVDFVAALQERVLVFDGAMGTEIYRRHVYINRNFEELSVSEPTLIRQIHKDYVEA
GADVLTTNSYGVNRDALARFGFAERTVAINKAAAELARGVVKDAKRQVFVAGSVGPISVP
GLVRVRRIELLTEQIAALAAGGVDCLIFETLPTRALAEDAVAALQAAAVTLPFIVSFAVN
EQGESSVGEPVERLLLPFGSLAPAAWGLNCGLGPDGLLGAVERAVHHTRTPVIVQPNAGM
PKEVDNRRITLCSPEYLATYAKRYLDLGARGIGGCCGTTPDHIREIARALRPLAQQRIEI
KAVPGEATALKPAVPLVEKTKFSAKLARGAWVTSIELVPPRGYNLADVVAKAAQCKAAGV
DAINIPDGPRASARISPLVTALEIQQKAGIEAMLHVCARDRNIISLQADLLGCAAVGLQN
LLFITGDPPKLGPYPSASGVFDVDSIGLVRLQARLNRGLDLGGQGIDPQTRAVIGVGADP
NALDFDREVRRFREKVEAGAEFAITQPVFAAEPLFRFLDAVADLKLPVLAGVWPLASFRN
AQFMKNEVPGVVVPDELLTRMGAVESRDDQRKVGIEIAREMVAKIRHRLAGLQVSAPMGN
IATALAVLAP
>A0A1Q9YHZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibaculum rodentium|TrEMBL
MMDIYKEQMAQELPRLFDGAMGTLYAQSTGMSSDLVEAANAANPEAIRSIHGRYLEAGAQ
CLLTNTFALPLVESEMALPLVPAAVNNAREAMAEAGCTVPLYASLGPADPGHPERMLSLV
DAFAACGVNRFLFETQAEFAPLRPAIDRIRETVPGAQIVVSFAVEADGLTRAGLEVQPLF
EEATPLVDGLGLNCLQGPAGMVKLVESLHWDKPLVVRPNAGSPSVTGHRMTFTAQPDYFA
QVLTPLCARGISVGGCCGTTPEHIQALSRYLDQADWQQDDLPEPEKDAGFVKRCPDNAVM
ALFERESKPIFVEADPPATDDVLPWLAAVKRLKNAGADVITVSDNPVGRPRADSCMLSAL
AASQEDMLMLPHIACRDKNRNAIRSLVTGLSAFGVHQCLVVTGDPVCEEDRSEVRQVYNF
NSRRLAAYIQVLNETVLQTPMCVMGALNVNARNFDIQLRLAKEKIANGVQVLLTQPVLSE
RGLENLKRAHEELDCRILAGIFPVVCERNALYLQNEVSGIELDERIPGLYAGLNREEAED
LALRLSLDVMRAVDAYCDGWYIMMPFRRTQLVARIMGAATDTDMG
>A0A2N1U749|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium HGW-Planctomycetes-1|TrEMBL
MDTTGNRLSRALEKKDGFVILAELTGGPNFSFAPLDKFLTAFNDSGGRDIPAGFNFVGVT
NPQSPGGVANIEPSDAHRHIVSKKLLGGLDFIPHISCKDMNADAITSLLAAHKAAGVESI
FVITGDKPVSAKGVFELESVNLLNEITRLNNKAYMSAKPQELGSVKQFFAGAGVSPFKYN
EESQMQQYFKMEKKIACGAKFLITQVGWDWKKSVELMRYLKDANLDTPVIGNVYLLSTLT
PAPRLMHDIKLPGCFVSDELLAKVYSEKIDGHIERAAQQVAMYKSSGAAGVDVGGVPNYE
MFIKILKRAAEIGDDWRQYKDNLCWPAKKAFYLYDDAGSRKEPSKAKKTFNHRFFNFMHA
AMLDPQHKGFHCFKKTMKFLGADKGKGFVYKSFNTFEKSIKYCLFDCEECGDCYLPENFS
LCTIGGCEKGMDNAPCGDSTADGKCGNNLDRECIGDRIYKAAAAEKDGLEKLRKIINKPR
KPELEHTASIINYLFGRDHTMKNPLISIGELVHASIPKTGQIMKQLHELGEDAFTRPSPE
LNYIKALIESQVADGADYIEVNIDQFGEFDPQLSVKLVKEYVKLVRKYGKGVPVCIDSSD
DNVLVAGLKEWYNTSEKVAAPLINSIKDYTIDTLMPLKKHFDYKFIGLLISEDPQASSTV
EGLYNLAKRIYDAAVNKYGFKPDDIFFDSTVFPLAIDMPMQPGAMSFTYRAFNTIKRIKT
DPLLKKCHFSLGVTNCVRDLPARRIGVTRAYTEVAMRYGLDAGIVNVAHQLGIKPADPEL
VKLVEAFSNMDGASERLTESMKLMGEFCAKNRKASI
>A0A7R7TBY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus thermophilus|TrEMBL
MKIRDLLKARRGPLFSFEFFPPKDPEGEEALFRTLEELKAFRPAFVSITYGAMGSTRERS
VAWAQRIQSLGLNPLAHLTVAGQSRKEVAEVLHRFVESGVENLLALRGDPPRGERVFRPH
PEGFRYAAELVALIRERYGDRVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIGIPILPGIMPVTSYRQLRRFTEVCGASIPGPLLAKLERHQ
DDPKAVLEIGVEHAVRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGLRPASGQP
>A0A846QGM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobaculum xiamenense|TrEMBL
MRHNLIDELSRRVVLADGAMGSRIFEKGVPAEACYDELNLTRPDLVAEIHAEYITAGAEL
IETNTFGANALKLERFGLAAQTRLINRRGAEIARRCARDIAWVGGSMGPLGRLDELPDAS
RIAAIYAEQAEALAEGGVDVLFLETFSRLEMLLPAVTAVKQTTNLPVVAQMVFTGQGGSF
TGVSPSECLQALADAGADVVGINCGAGPLGVLEALRKAGSPGRPLSVFPNSGYPERSGDR
LLYGSAPDYFADAVMRCVKLGARLVGGCCGTTPQHIAALRRRLDLHTGSTAHTETIQNIT
GGDGSTPELPPTRFSLNLGQRKMVLVELDPPKHLDATQALDAADALADAGVDAITIAENP
LAVPRLSNTALAGMIRRRTGAEVIVHLTGRDRNLIGMQSTLMGLAVEGLQNVLAVTGDPP
PSGTDDVIKGVFDLRSFDLISLLRRFNEGVNHHGDSMRLRTNFCTGAAFNPNTKNHALQV
RRMERKIECGARYFLTQPVYTREAIDEVLDLTAHIDVPIFIGIMPLVSSRNAEFLHNEFP
GISIPDDTRRRMREAGDRGVEVGTQIAWELLEYAWPHFAGVYIMPPFNRYGIALDLMQRL
RAGGLLES
>A0A2V6GIP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRSSPPTFSFEFFPPKTPEAAEILYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
ELVERIQHTTKLDPIPHLTCVCHNAEEIEAILLRYARSAIGNILALGGDRPPGVAYDKSR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGVGVAGFPEGHPATPNRLVEMDYFKAKVDAGA
DYIITQLFFDNRDFLDFRERCVLNDIHIPIIAGIMPITSMRGVKRMAELAGGARFPAGLL
RTLQDCQSDPEMVRHVGIQHALEQCHDLLDNDVAGIHFYTLNRSDATRVIFDSLGIPRHR
NAQASSV
>A0A2V5X7F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRRDSPTFSFEFFPPKTPEAAEILYQTIRDLESYMPHFISVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCICHSEEEIEAILLRYARSAIGNILALGGDRPRDIPYDKSR
DSFQHAVDLVKFIRRFNESGAHPEDRGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYMVTQLFFDNRDFLDFRERCALAGIHIPIIAGIMPITSISGFKRIAELAGGARFPAKLV
RALQRCENDPEGVRRVGVHFALEQCHDLLDNNVAGIHFYTLNRSDATRVIFDSLGIPRRR
SAQAPTA
>A0A1X1HJ14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKNKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNHISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3N5ILD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroococcales cyanobacterium metabat2.561|TrEMBL
ELFAGAAVDVQSKSWSGLQRRFERKIEAGAQFFQSQLVTDFECLDKFMQQVASLADKPVL
AGIFLLKSAKNAVFLNKNVPGVQIPDQIIQRLADAAHPLEEGIKIAAEQIKLAQQLCQGV
HIMAIKREDLVPKILDAAGIPPIHN
>A0A2V5X6W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
RTPVHIEHKAEESLLDKIASGKRVVICELDPPKTLALEKYFGGAQALVDAGCDAITLADN
SLAILRVSNLAVGAMLKERFDITPLLHLSCRDRNVLGLQSELLGMAALGMRHVLPLTGDP
ARVGDHPGAASVYDVNSVELISIIKQLNSGFTHAGKPLKAATNFVIGCTFNPNAKNLDAQ
VQRLERKVAAGAQFVMTQPVFDVDLVGEMHRRVQHLRIPIFTGVWPLQSAKQAEFLHHEV
PGIIVPDSVRAELASHDDEGAQACGIRLAEKIITAALDFFPGVYLITPFLRYESTTRLAK
FARSL
>A0A0T9U892|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia intermedia|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEETLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A435MUA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.003.01.2.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A1X1HFU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis subsp. oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKHIHQATHALFNHQSLG
>A0A351WIZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MDALCIKDLLDRRKSPLLSFEFFPPKDGLGMASLETAAAQLLSAKPDFATVTYGAGGSTR
ERTLQVCDLLRQMGYGPIMPHLTCVGSTRDELLALADRLHGLGYRNIMTLRGDPPQGETV
FQAVTDGLAHASDLVALLKTAHTDFCCGVAGYPERHPEAPSAREDIVHLKQKTDAGADFI
TTQLFFDNRCYFDFVEACRTAGIRQPILPGLLPAISLKQAQRMTARCKTRLPEELIRQME
EAGSEGDAAEEVGIQWAQKQIEELLGRGAPGIHLYVMNRSKAALTPAIADCFRRFRG
>A0A2U8V4L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NEAU-S7GS2|TrEMBL
MALGTASTRTDRAHTVRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVRHPDGVGYAADLVRLIKESGDFCVGVAAFPEMHPRSKDWDTDVAHFVA
KCRAGADFAITQMFFYPEDYFRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A552JG53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis wesenbergii Mw_QC_S_20081001_S30D|TrEMBL
MTTRLRRAIQDREFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQLKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVATIADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAAHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDAAGIPPIHN
>A0A5Q0P361|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter wanghuae|TrEMBL
MSKRIPISFEFFPTKTDVGAEKLITVHQELQLLNPEFFSVTYGAGGSTRERTLSTLADFN
GKGTPVAPHLSCIGDSKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQAENFDLDIKRFCDKANAGANAALTQFFFNPDAYFYFV
DRLQKEGVHIPVAPGIMPITNASNLIRFADGTGAEVPRWIRKQLATYGDDTASIKAFGHE
VIIKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A2G4E175|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. NZIPFR-PS5|TrEMBL
PAAPHLSCVGDSKADLRSLLTQYREAGIKRIVALRGDLPSGMGMASGELRYANDLVSFIR
EETGDHFHIEVAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFHFVERV
QKLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTASIQAFGEHVIT
EMCERLLHGGAPGLHFYTLNQAEPSLAVWNNLKLSA
>A0A2L1UFN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus larvae subsp. larvae|TrEMBL
MRPDLRLALQHQLLTGDGAMGTYLYQLGFPVGISYEELNLLQPQVIADIHRRYYEAGAKI
IETNTFSANKEKLSKFGLEQEVKRINRAGADLARQTVGDDAYVLGAVGSIRGSKRKNVLE
ADVRIAFHEQVEALLEASVDGLLLETFYDLDELLIALRLIRNLSDLPVICQFTTEGNHTT
HDGIPLQEAFERLKDEGADVVGFNCVSGPNGIMQSIGRIHPLEQVPFSVYPNAGIPDYVD
GRIVFGATPEYFAETALRFADLGARIIGGCCGTTPEHIAAISKALRGYVPSAEQAFRLRG
TETGRDEEHPVISTGTAETGDSSYMDGVPNLVDLVQQRPTVIVELDPPRTLDINKFMVGA
KALKDARVDAITMADNSLAVTRMSNLALGALVQQRLNVRPLVHIACRDRNSIGTQSHLMG
MDALGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNKGLAFSGKPLKKKARF
VIGAAFNPNVKYLEKAVQRLEKKIAAGADYIMTQPVYDHALIERIHESTKHMDVPIFLGI
MPLASGRNAEYLHNEVPGIQLPDETRGRMAGLEGEAGRAAGTEMAKELIDTALQYFNGIY
LMTPFLFYDMSVALTEYIWGKTSSRHPLLSRV
>A0A073J8Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter pseudonitzschiae|TrEMBL
MTALSFEVFPPKSIDAGFRLWDTVQALTPLEPRFFSVTYGAGGSTQDLTHEAAQTLRRSS
GLPVAAHLTCVGATREKVLKTAAKFADAGITDIVALRGDPVDGTDFQQVEGGFANSIELV
EALADTGRFTIRVGAYPESHADAADSAQNIAWLKAKIDAGASEAITQFFFEAETFLRFRD
ACVKAGITAPIVPGILPVGNWASIQKFASQCGADVPVTLAQGFENAARDGNSDLFALAHC
TEMCDELRSEGVDALHFYTLNRPDLTREACRALGLIPAAAMRNVA
>C5WDM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Ishikawaella capsulata Mpkobe|TrEMBL
MVFFHVNQREILNQSISKLNGDVNVSFEFFPPRTNEMKKILWQSILQLSSLKPKFVSVTQ
GVNPEDCQFTYNVIKDIKNNTKLEVAPHLTCINNTCEELHMIAQKYWSNGIRHIVALRGD
SFKNKKNARIYASDLVYLLKKIGDFDISVAAYPEVHPEAKSAQADLINLKRKFDNGANRA
ITQFFFDIDSYLRFRDRCLAIGIESEIIPGILPILNFKQVQKFASFTNVKIPNWMKIMFQ
GLDNPEICKMIGASIAIEMVKILSYEGVKNFHFYTMNRYDISYAICHTLGIK
>A0A1H7K2J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas daqiaonensis|TrEMBL
MSTQEHPLGISFEFFPPNTDAGRERLVGVRDALASRAPRFFSVTFGAGGSTQDRTLNTVR
MVRESGFTTTPHLSCIGSDKGALRELLARYREDGIESLVALRGDMPSGMGGGGIGQLRYA
NELVEFIREETGDHFEIAVAAYPESHPQAANLEQDLTNFARKMKAGADIAITQYFFSAES
YFHFVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIG
AFGEELVTRLCQRLLDGGAPGLHFYTLNQAKPVLRILDNITG
>A0A4P8Q9A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. SGAir0440|TrEMBL
MASSASLNLADARALLLSPLGPVARAGSNRDAVRVSFEFFPPKTDEAEANLWKAIRRLEP
LIPAFVSVTYGAGGSTRERTHRTVQRIITETSLRPAAHLTCVEASREEVDEVIEGYKTIG
VDHIVALRGDPPGGAGIGGVYQPRADGYANATELTAAINRIGGFDVTVGAYPERHPESPS
IDYDIEVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLQ
RMCGACGASIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETAAAQ
>A0A2V5C5I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. AG1095|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRGIARDYWDSGIRHIVALRGD
LPPGSGKPEMYGSDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMSAMFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAMGG
>A0A373PDH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. OF03-13|TrEMBL
MKLSEEMKNKTLLSFELFPPKTEKGLQNLPGTIDHLMKYNPSYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLDQYLADGVDHMLALRGDIPLGETTTCGDFD
YATDLVKFVRDTYGDKFEIAVAGSPEGHISCRSLESDIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIRKAGITMPVDVGVMPILDQAATINMALSRNGCVMDRELSRMISRHWLFPN
PFAAKDAEGKPFDVFYDKKVAEFKEEGIEYTVKQIDAYRALGVNGIHLYALNKWKDVSEI
IDRSGLCTLV
>A0A2M8YH56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. 67|TrEMBL
MVNPAQPWPASDITHAYSLEASTKDIAALSAAAPRILSGSTIAIPYLPRENDDARLAAAR
AVRRLGFEPMPHLSARRIASLAGFESFVQRAAAEAGVERCFVIAGDPHTPMGPFADSAAL
IDTGVFERAGMQVIGVGGHPEGHPVMSKAEQWEVLERKCHSIEMRGMAPLIVTQFAFDAD
IVLTWLEALRARGINHPVRVGVPGPASIAVLARYAALCGVGACASMWSKYGVSIGKLFGT
AGPDLFVERLATGLTAAHGKVSLHFFPFGGIAQSVKWIEQYRTRTDPGP
>A0A0B8N178|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia seriolae|TrEMBL
MGPRPDGSIPFSVEFNPPRDAAGEARLWRAAREFERLHPAFVSMTYGAGGSTRDRTIRIT
GQLARETTLLTVAHLTAVDHSVAELRSIVGAYADSGIRNLLVLRGDPPGDVLGEWVKHPE
GVEYAEDLVRMVRELGDFHVGVASFPQGHPRSANLEDDTNFLVAKLRAGAEYSITQMFFD
PEHYLRLRDRAIACDPVEGAKPIIPELMPITSLRTVERAVELCGRPLPPKVMERLHKAAG
DGPEENRAAVREVGIEIATEIAERLIAEGAPCLHFITLNFAKATGEVLANLGYSMSPAPA
TV
>A0A2J6S975|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyaloscypha variabilis F|TrEMBL
MHIKDMLAEAERSGRPTFSFEFFPPKTAQGVQNLYDRMDKMHGLGPSFIDITWGAGGQLA
DLTCEMVDVAQSQCGLETCMHLTCTDMGKDAVDQALKKAYSAGCTNILALRGDPPREKEK
WEATEGGFLYARDLVTHIRQSYGNHFDIGVAGYPEGCDDQDDPELLLDHLKQKVDAGATF
IVTQMFYDVDNFINWVSRVRAKGITVPIIPGIMPINTYASFLRRASHMNATIPPEWSADL
EQVKNDDAAVRSRGTILVAEMCRKILASGVHHLHFYTMNLAQATRMVLDELKLTPSDQRP
LKQALPWRQSLGLGRRDEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDT
YGTALRGTNEQNRKRWGEPTSIKDIADIFVKYLEKDVDSLPWSEAPITSEADAIKGDLIS
LNKRGLLTINSQPAIDGVKSSDPVYGWGPNNGYVYQKAYLELLVSPKLIDELIARIERNP
DLTYYAVKKVGNVKTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCYSSMSLSRQLIENIMETWHLVNIVHNDFHQAHGLFPLFDDLEVEDLDKVFEAGQTNG
NGEANDVNSQTNGVEDAPLTNGSTAH
>A0A059JE18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton interdigitale (strain MR816)|TrEMBL
MHIKDKLALAEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLA
ELTCEMVHVAQSVYGLETCMHLTCTDMPREKVDDALQSAFKAGCTNILALRGDPPREKEA
WEQTKGGFRYARDLVQYIREKYGNHFDIGVAGYPEGCEDEEDPELLMKYLKEKVDAGGTF
IITQMFYDADNFLDWVKKCRQAGINVPIIPGIMPISTYAAFIRRTNWVKCAVPKGWMEAL
EPVKNDDAAVKQIGKALVSEMCRKLLENGINHLHFYTMNLAQSTTMVLEELNLKPSTETP
LQKPLPWRKSLGLGRREEDVRPIFWRHRHQSYVARTQSWDEFPNGRWTDSRSPAFGELDV
YGIGLKGTNEQNIKLWGEPKSVRDLSDIFVRFLEHKLDRLPWSESAITQESEIIKDDLID
LNNRGFLTINSQPAINGAKSSHPIYGWGPRNGYVYQKAYLELLISPALIDEVIRRIESNA
DLTYHCINKDGELKTNSSDTPNAVTWGIFASKEVIQPTIVETVSFLAWKDEAYRLGDDWA
KCHDASSASRKLIQNTMDTWYLVNIVNNDFHKTHDIFDLFKGLVLKDIDTEVSGTQQATE
LAENGTHSEAPASKSEKQAVSAN
>A0A418XQN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia cavernae|TrEMBL
METDNFSIEFFPPKTAEGAEKLRATRDKLALLKPKYFSVTFGAGGSTQQGTLDTVLDIKQ
AGHVAAPHLSCVGASRESLRAILKQFQSHGIDRVVALRGDLPSGYGGGGEFRYASELVEF
IRAETGDWFHIEVAAYPEVHPQARSPQDDLQAFARKVQAGADAAITQYFYNADAYFAFMD
QTRKLGLDVPVVAGIMPITNYSQLMRFSEMCGAEIPRWIRLKLASFGDDSASIKAFGLDV
VSEMCVRLLNGGAPGLHFYSMNQAAATTALWERLSAAPSAR
>A0A1F4BZX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_65_24|TrEMBL
MKSVRLWSVRHAGALEKLHSLFMRVAPRLRRGVAWLGPERVERLIAPAERTIKGLFFDCR
MCGRCTLSSTGMACPMNCPKRHRNGPCGGVAADGSCEIDPGMRCVWLEGLDGSRRMSGAD
KFASIQPPADASLRGSSAWVRTIMGKDAVPQAPPPGQGHGARERGLLETACRSGRFVVTA
ELSPPDSADPQDQLRRATAFRGILDAINVTDSAGANCHMSSLAASALLVANGYEPVFQVA
CRDRNRIAMQADMLGAAALGVRNLLAITGDGVGNGDHPDARPVFDLDSVSLLEIARGMRD
RGAFASGRTLAVRPDLFLGATINPFAPPFEDRLINFAKKIAAGAQFVQTQYCFDLAMLEA
FMRQVRSRGLDRRCHILVGVGPLPSARTARWMLARVPGVHIPEQLLHRIEQSADQKREGA
KICVELIRALRRMEGIAGVHVMAHRNEELVPEILRESGLTQERNNAPGLPGVT
>A0A7K2KWQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID6041|TrEMBL
MALGTASVRSDRARTVREILASGGTSYSFEFFAPRTEKGEQVLWNAMRRVEALGPSFVSV
TYGAGGSTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNVLGQYADAGIRNMLAVR
GDPPGDPLGDWIEHPEGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSLDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSAVKAGCETPIIPEVMPVVNVKTLDRLPLLSNAHF
PADVKERILAVKDDAAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTAIEIYENLGL
HQQS
>A0A6N7M9H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaeta sp|TrEMBL
IAIQSDVLGAYALGLKNILCLTGDHQVFGNHSTSKNVFDMDSIQLIQTLKNMRDEKVFIC
GDEIKNSKKAPVVEPRIFIGGAANPFGDPFEFRVIRLAKKVNAGVDFIQTQCIYDMERFE
KWMEQVRERGLHKKVKILAGLTPLKSVRMATYMRDSVAGLTVPDYYLERLAKAEDKAAEG
IKICVEQIKRLQEIEGVAGIHLMAIEWEHRVPEIVEAAGLLPRP
>A0A7Y5G2M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MQTLREKFFQTADFLFGVELLSIRGSMAEKSAVKARDFASELVDCPEIDWISITDNAGGN
PQLAPHALGKPILYAGKEVVIHMTCKDHNRNGLESEAWFLSSEGFQNILAMTGDYPVAGN
EGMAKPVFDLDSIGLICMLNKMNRGFEYRQRGGRHEAQRLGKTQFFIGAVTSNFKLREGE
VVPQYLKLQKKIECGARFIINQVGYDARKIHELRLYMDHHGMKHVPLIGNVYVLNPRVAQ
IFHDKKIPGIVVTPPLLELCLKHGRSAEQGRSFFYEFAAKQIAVYRGLGYRGAYLGDVC
>A0A822QNB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pseudopneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQILDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKSILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A1G0H9Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_38_11|TrEMBL
MTTLEISFEFFPPKTDTGMTNLLQAATTLASINPNFFSVTFGAAGSAQTHTPNTVFKVQE
HTSVPTAPHISCVAATKEMIKALLEKYIQNNIMRLVVLRGDMPSDTPEATHHFQYAAELL
QFIRQETGNHFTLSVACYPEFHPQTTDHKRALFHFKEKVDAGANNAITQYFYNPDAYFKF
LDSCRKMDIHIPIIPGIMPITNYEKLVLFSKTCGAEIPRWLLYRLESYQHDAKSFEQFSE
EVVMQLCEKLIAGGAPGLHFYSLNKAEPSINILTSLKLHQSHPLFS
>A0A1I0SLQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas otitidis|TrEMBL
MSQDRRYSFEFFPAKTEAGHEKLLATARTFAGYKPDFFSCTYGAGGSTRDRTLQTVLQLD
GEIQVPTAPHLSCVGDSKAELRALLAHYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VEFIRAETGDHFHIEVAAYPEVHPQARNFEEDLKHFVNKVKAGADSAITQYFFNADSYFY
FVDRVRQQGVEIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYADDTASIQAFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2E4NH92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MVKPKVSFEFFPPASEKMAEILWLSVKRLAPLEPTFVSVTYGAGGSTRERTHSTVKRLRD
ETSLEPAAHLTCVGATKTEIDAIIRSYWDAGIRHIVALRGDAPGDNGKYQPHPKGYANGA
ELTKGIKKIADFFVSVSAYPEKHPDSVSRRADIEMLKQKVDAGACQAISQFFFEPEYFFR
YRDAVAAAGISIPLIPGIIPVINFTRIQSFAATCGAKIPSWMTDQFDGLEDDPQTRKLVA
ATIAAETCQKLAAGGVEQYHFYTLNQADLTYAICHILGLRPSAAGF
>A0A2E5PGZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MNNTPLVSFEFFPPHDDAGETRLWHVMARLAPLGPAFVSVTYGAGGSTRKRTDRVVRRIH
DETSVPVAAHLTCVGASREEVDGIANSWWQAGIHHIVALRGDMPSANAPYAPHPEGYADA
AGLVTGLRKIAGFEISVAAYPEFHPDSPTPEADLDNLKRKVDAGATQAITQYFFNNDDFL
KFRDRIEAAGIRIPVIPGILPVTNFAKVVEFSDRCGAKVPDWMAKLFEGLDGDPDTLKLV
SLSVAVDQCRALQAEGVPAFHFYTLNRAELTYAICWRLGLRPLDAAA
>A0A3D4E732|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
NTPIDDLKSYADDLWNQGIHHIIALRGDMPSDLQWPLDPDKDYFQFTSNFVEAIKSWHDF
EVTVGAYPEKHPDSPSLALDMIALQKKCEAGADRAISQFFFDNQVFLTFAEVCKHMQIAA
PIVPGLLPIHDFQSMCAFAEKCHTTVPPWLRERFENCSNPKQTAIDTLYEQAKNLIDHGV
PHLHFYTLNKADIVYDVCKKLGY
>A0A3N9P5N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MTVKDILNSTPISFSFEFFPPRTDDGWDNLFHSIADLMPLKPAWVSVTYGAGGSTRDRTH
DLVMRIQKETNLTAVAHLTCVGSSQDEISGILDRYVKNDVLNILALGGDPPKDMPDWRLQ
PDGFRYAGDLVRFIKRQHPAISVGVAGFPEGHPATPNRLLEIDHLKAKVDAGADYIITQL
FFDNRDFYDFCERCEIAGIHVPILAGIMPILTKKGMYRMVELAAGARLPARLLKLISRAD
SDDYVAKAGVHWASEQVRDLLDNDVRGIHFFTLNKSKATIQIYESLGVRSSEQFLL
>A0A439D154|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylaria grammica|TrEMBL
MHINDMVADAERTGEPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFVDITWGAGGRIA
ELTCDMVLQAQTFFGLETCMHLTCTDMGEEKVNDALQRAYKAGCTNILALRGDPPREKEK
WEATDGGFQYARDLVAHIRKKYGNHFSIGVAGYPEGCDDNKDEESLLDHLKEKVDMGGTF
IVTQMFYDADNFVRWVGKVRERGITAPIIPGIMPIATYASFLRRAHHMNCKIPEKWMAAL
EPIKNDDSAVREVGKVLVAELCRQIMSAGIVHLHFYTMNLAQATRMVLEELDWLPSSQRP
RKQPLPWKQSLGFGRREEDVRPIFWRNRNKSYISRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNESNRKKWGEPKSISDIASLFARYLEKDLDSLPWSEAPLSGEAVSIKDDLIN
LNKRGFITINSQPAIDGVKSTHPIYGWGPPNGFVYQKAYLELFVHPELYDEVIRRIERRE
TLSYYAVNLAGTFTTNAPSEGPNAVTWGVFPGKEIVQPTIVESVSFLAWKDEAYRLGNDW
ARCHEANSPSRALIEGIMNQWYLINIVNNDFHDTKAVFELFDGLEVKDLETPVFSAPHTN
GTNGTHKETSSIAAPN
>A0A2G4IMP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MMPDSGSGSPPIRVSFEFSPPRTEVLSEQLWVAIERLAPLKPNFVSVTYGAGGSTRERTH
EIVDRIQREKGLRAAAHLTCVAATREEVDAVAQRYWASGIRHIVALRGDPPSGVGHYEPH
PGGYAFAADLVTGLKKVADFEISVAANPEGHPEAPTRAADIDNLKRKIDAGACRAITQFF
FDVDIYRRFMDQALAAGIKVPILPGIIPVTNFVSTANMAIKAGAAVPQWLSKLYEGLEDD
VETRRLVAATVVAEQVRQLRQDGVQDFHFYTLNRADLTYAICHVLGVKP
>A0A428KJ46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hymenobacter perfusus|TrEMBL
MKVTEHLTRANGNTLFSFEVLPPKKGENIQNLFSNIEPLLEFKPPFIDVTYHREEYVYRQ
HANGLLEKKTVRRRPGTVGICAAIKNRFDVDTVPHLICGGFSKEETENALIDLHFLGIDN
VLALRGDPIKSEGRFVPEPDGHAYACDLIGQVSDLNKGAYLDEEQDDVWATNFCIGTAGY
PEKHFESPNSGADIRYLKHKVDRGAEYIVTQMFFDNEQFFQFEQKCRAAGILVPIIPGLK
PLTTKAQLTALPRSFYLNLPDELVDAVHLAPDNAAAREIGIEWCINQSRELMAHGVPCLH
YYSMGKSESIRRVASALF
>A0A3S9FUH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1D.F.Ca.ET.043.01.1.1|TrEMBL
MSARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRRPWKREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>E1IW13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli MS 145-7|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2E9J4B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichales bacterium|TrEMBL
MTEEYLKLRDVLDSGEFAITAEVPAPVSASSAEMEEKIKILKGSVHAINVTDNPGATAHM
SSLAGSVIVRNQRIDPILQITCRDRNRLAIQSDLMGASALGIDNVLTLAGDPIKNGDQKD
AKPVFDINSKTVLSIMDVMNNDGVIMSGKELQSKSNFFPGGAAVVHEPEDNWDPKALSEK
ASFGAKFIQTQFCYDAELVKRYMQRIVDAGLSERMYFIIGIGPLRSEKSAKWMKDKLFGT
VMPESVIKRMEESNDQIQEGADICAELIESFKEIEGVHGAHLMAPRNLSAIPRTVERSGI
VI
>A0A2D7C2C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSFNDHRKNNQFSLINNVPLGIKVSFEFFPPKNSKMNERLWFAIQKLAPLSPXFVSVTYG
AGGSTRKLTHETVVKIQKETDLTAAAHLTCVSASKEEVDDIAKNYWDAGIRHIVALRGDP
PNNQKAFIPHPNGYKFASDLVLGLKKVADFEISVAAYPEKHIEAHXKEDDLDNLKRKIDN
GATRAITQFFFDPDIYLRFRDDAXKRGISVPIVPGLMPITNFEQNIEFAKSCGADVPKWL
LNLFKGVEEDDEARKLISGTIAVEQVRRLVENGVNXFHFYTLNRPDLTFAICRVLGIKSN
LIXKLNDC
>A0A5A9FH87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. B21|TrEMBL
MTAPTSAQPSVSFEFFPPKSEKMEQSLWQSIRRLAPLSPGFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGRYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDVYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPKKLAETFEGLDD
DPETRHLVAATVAAEQCQELQAQGVHDFHFYTLNRSDLTIAICRMLGVKAKAAPAAAAVA
G
>A0A0M3DF25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraclostridium benzoelyticum|TrEMBL
MSLLREALESGKFAITAEMAPPKGIDLSRLVECAKAVKGRVHAVNVTDFQSAVMRTTSLT
TCKLLKDEGLEPVLQVTGRDRNRIAIQGELLSAGVFGIENMLALTGDHTIVGDHPQAKPV
FDLDCVGILQTAQKLSEGTDMVGNQLKGSPEFYLGASVTPRYTPIEIQLLKMKKKINAGA
KFFQTQAVYDIDTMREFKEHTKEMNTKILAGIIPLKSPGMAKFMNENVPGIYVPEELIDR
LRSVGKENWASEGIKIAGELIQQLRDEDLCDGVHIMAIGSEENVPAILDAAKL
>A0A0V8J1J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fictibacillus enclensis|TrEMBL
MGLLKDLESKILIADGAMGTLLYSYGTDCCFEQLNLSHTEQIQSIHQAYIQAGANVIQTN
TYSANYIKLQRYGLEEQVKELNSAAVSLAKKAAGGNAYVLGTIGGIRGTGPSSLSLEEIK
RSFREQLYCLLLEGVDGLLLETFYDLEELEAVLKIARSQTDLPIISQISLQEVGILNDRT
PVNTAIKRLEELGSDVVGLNCRLGPFHMIKTLEEVEIPKHAFLSAYPNASLPSYVDGKFQ
YEGDAEYFKNSASLFRNQGVRLLGGCCGTTPAHIEAFAEELNGLSPVTEKNVRQRPEPIA
VASSGQKPQISLPEILQERRSVIVELDPPRKLDTTRFFEGAKALKEAGADAITLADNSLA
SPRICNTSLSSLAKAQTGAQPIVHLACRDRNIIGLQSHLMGLHTLGLHDILAITGDPAKV
GDFPGASSVYDVTSIELIKMIKQFNEGVSLSGKDLGEKTHFTVGAAFNPNVKALDRAVQR
AEKKIEAGADYFISQPVYSEEKLLQFHEAVKDLPVPVYVGIMPLTSSRNADFLHYEVPGI
KLSDEVRNRMAEFKDDPLAAAREGLAISKSLIDAATELFNGIYLITPFMRYELTVELTRY
AYNIAPQIVRRIQNV
>A0A7L9BH13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flammeovirgaceae bacterium|TrEMBL
MKVIDHIKKANGKTLFTIEILPPLKGENIRSLFDHMDPLMEFKPPFIDVTYHREEYVYKK
QENGLLEKRSVRKRPGTVGICAAIQNHYRVDTVPHIICGGFSKEETENALIDLHFLGIDN
VLVLQGDAIKNEGRFTPEPDGHQYASDLLQQVVRMNKGIYLDDELLNTAPTDFCIGVAGY
PEKHFAAPNLKTDLKYLKLKVDLGAEYIVTQMFFDNARFFDFVNRCREAGITVPIIPGIK
PITTKSQISVLPTTFHIDIPEELADEVEKCKDNAAAKEVGIKWAVQQSRELIKAGVPTLH
FYSMGKSDPIYKIAKELF
>A0A8C1BK38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MKAKSFLTSCIDSNSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGGMNTLAADRQNLTGLLQLMAK
GMSEPIKDNDAAIRNYGIQQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAE
DPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELT
DYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLA
PETNLLKDELEKVNRRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSEN
VTALLQVLKKYEPRVNYHIVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFM
YWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFT
LLDSPPETQED
>A0A0R1XU47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrilactobacillus composti DSM 18527 = JCM 14202|TrEMBL
MGNLAQALQDQVLVADGAMGTLLYSQYGISHDFESLNLTHGGDILQIHQAYIAAGADVIQ
TNTYAANSIKLSRYGLENKLTAINEAAVSLAHTAKVASERPVYILGTIGGIAGSTDITDP
DLLTPAAIDASVRQQVEVLLATKAIDGLLLETYFDLAELKRAIKVVQSLTDLPIVANVTM
YEPGVLQGGTTLTQALSELAALGVAAAGANCHLGPYQMNEALEKTQLPLGTPLAVYPNAG
LPNMEHGQLIYDGSAAYFRTYAETFRQKGAHLIGGCCGTTPEHIAGLFAGLKSRQPVQPE
INVQVRQQQAENQAAVARTHPFLEAVKTKKVPLVELDPPKTLRTDRFLKSAQALAEAGIG
AITLSDGSLATTRISNLALAAKLKLEYGITPLVHVTTRDHNLIGLQAEIMGLSMLGLDDV
LVITGDPAKVGDLPGATSVYDVHSTELISYFKKYNEGISPTGRKLGKACSFSVGAALNPN
VRNLDRIPKTIARKVDAGADYIITQPIFDPQIAVDLAKVVADNDIQVPIFVGVLPLLSYR
NARFLHHEVPGIRLSEDTLTRMKAAEADGNEREVGLQIAEELVDVICEHFNGIHITTPMQ
HAEISGALAQYVKAKNTAKV
>A0A669QQU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phasianus colchicus|TrEMBL
MVNENQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVHGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETSLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIFGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPPQQ
>A0A1M7Y379|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila aestuarii DSM 18488|TrEMBL
MELKTESKLEKVFKSGQIAVTSECGPPRSSDPAHIIEKGHLIKNHVDAINITDNQTSVTR
ICSLAACVHLKNEGLEPVLQMVTRDRNRIALQSDLLGAASFGINNVLCLSGDHQSFGDHR
QAQNVFDLDSMQLIQTVRHMRDEGKFLSGDEIKVPPKFFVGAAANPFGDPFKIRVPRLAK
KVAAGAEFIQTQCIYNMDRFEKWMEGVRERGLDEQVYIMAGITPMRSVGMAKYMKRAVPG
MDVPDELIERLQGVEKKQQAQEGIDIAVEQIQRLKEVKGVAGFHIMAIEWEEKVPEIVER
AGLYPRPTFD
>A0A4U1A0G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus sp. IMCC35007|TrEMBL
MLRVFSNQLMDPENFVVTIELVPGRESFGASTDTLVGIAKDAFIDGRVSAVSITDNPGGN
PSLSPDVLGQEIFKHGLDVIVHFTCRDMSRVGMESRALQLARMGIKNILCVTGDYSGKGF
GGRGTPVFDLDSVLLTRMMQGLSDRMVASGDPEPFFTGCGVSPFKTLKSECLAQYKKLDK
KIDAGSAFVITQLGYDINKFNELIRYHKEKNASIPVIASVYLLSPKAARAMNRGRVPGAY
VSDTLYKQVIQEWKTPREGLNAAIERAARLGVVLKAFGYRGIHIGGIHRSFKAIARILDR
MEEIEETWPNYLNDFSSKEKSSYYYYDKVIEDETVPASRPGLKERVIEHWPYKMFSFAHN
IFFDKTVGVAPICRKVATFLDSNNKSWLLKRGLEDPIKIPLLSCQSCGDCGIQHVAFICP
ESGCPKHTRNGPCGGSRNGTCEVYPDKDCIWIRAYNRLDHVGKLPTFLKDNVPPRNWELN
KTSSWINFHLNRDHQK
>F1TGC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MNIFSDRDYFLFDGAMGTYYSAKNKINTPCEFANISERENILNIHLEYIEAGANAIKTNT
FGANRYSLGCQQSEVDRIIKSGYDIAVQACLGQDVAVFADIGPIPDGKGANVEEEYKKIV
DVFLECGAKNFLFETFAGTDILTGIAAYIRLRLPETVIITSFAVYPDGYSKEGFFYIDIM
EKMYASGLVDAVGFNCISGPAHMYRLIKKADIRGKNIIIMPNSGYPGSERGRTVYYDNSE
YYAEKLVEIKNLGVKILGGCCGTTPRHIAAAAKLLTSPQSTEANTAISTHIETCELANES
IIDKLIKNKKPILVEIDPPFDTNWEYMLRDALILKQAGADIITIADSPLAKARAESTIMA
AKIQREVAIPVMPHITCRDKNLLGIKASLLGVHIEGIRNVLVITGDPIADIERSRIKGVF
SFNSSNLANYIKSLNSNVFCGQDIKIAGALNVNAVNFGAELKKAFTKIENGISCFLTQAI
YTKSAVENLLKAVETLNIPIFAGFMPIVSYKNAQFINNEVPGIDIDAEIIEKFRDKSREE
SEKLGMEITMDIVEKIYPHVSGFYLMTPLKRTGVICELIKKIKEL
>A0A8C2L0V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MKAKSFLTSCIDSNSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGKDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIITQLFFRAETFLKF
VKDCRAIGISCPIVPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNCRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQED
>A0A1Z8MTW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrionales bacterium TMED21|TrEMBL
MSALKQCMESLYYEVIPMKGYEAGLDHLNAGDKVGITCSPKQGIQYTLDTVAHIQPRGFQ
VTPHLAARQIKNRQHLADMVSFLTDQGVTSIFVPGGDVDVPMGDYDSSAAVLADLAEMDH
PFTKIGVASYPEGHPAIPDDVLFDALKAKQGIATHMVTQMCFDMXALLKWLKXMRDAGIT
TPVWIGLPGVMDRMKLFKTSLRIGVGQSAKYARKQKGLAGMLLRSSTYKPDALLKELKPA
MDDERMAVEGLYIFTFNQIDNTVQWSQEQLKRIK
>A0A1M7YAC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila aestuarii DSM 18488|TrEMBL
MKTDSKLEKILAAGHLAVTGECGPPRGCMPDKVREKAKYLEGVVDAVNITDNQTAMVRMS
SFAASVIVKQEGLNPLLQMVSRDRNRLSMQADIIGAYSLGIDTMLCLSGDHTRFGDHPMA
LNVHDLDSIQMIKMVKDMRDEGKFQGGAEIKGAPKMFIGAAANPFADPFELRVMRLAKKI
NAGADFIQTQCIFNVPKFEQWMEGVRKMGLHKKTYILAGVTPMKSVGAARFMQKRVPGMD
VPQELVDRMASVPKEEQAEEGVKICVETIQRLKQVEGVSGFHIMAIEWEEKVPEICERAG
LLPRPQV
>A0A1M3T683|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus luchuensis (strain CBS 106.47)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDVQDPARDLPYL
IEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPQVLSKLEEVKHDDDAVKRIGVDIITDLVYGIRDLVSPGLRGFHFYTLNLEKT
VSFILERCELIPPYTEIDDSDALVDGGNLSAMDSSSYIAPNGAPIRTLASRRSSVSSIPH
NRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEEDSNGLNAETAVIQPELLTLIDKKGWWTLASQPALNGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNPDDPDPIDIN
PANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDETK
NDVWLVCVVGQEFGAGTEAGSEEEEDEKKWMWRELANSQ
>Q0I416|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus somnus (strain 129Pt)|TrEMBL
MSYTKELDTLNQHMVDINGKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHAVVKRIKQETGLEAAPHLTGIDATPEELKAIAKDYWDGGIRRIVALRGDEP
KGYIKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPSWMAKMYEGL
DDDQTTRNLVAASIAMDMVKVLSCEGVKDFHFYTLNRSELSYAICHTLGVRPSL
>A0A1Y2BDK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naematelia encephala|TrEMBL
MKITEKLQKAEREGRPYWSFEFFPPRTAQGLQNLYDRIERMRNLGPEFIDITWGAGGKNA
DLTSSLVQVCQETIGLECCMHLCCTEMPKEKVEWALAQAKAHGCQNILALRGDPPHGSST
WKPTPGGFHNAVDLVKHIHKNYPGDFCVAVAGFPQGHPETPDTPDGRHQEMLWLKEKVDA
GADFIFTQMFYDTDILFDWVRRVRAAGITIPIVPGIMPIQNWEKFQTWVKREKIVVPPHF
YDALNPVKGDDEKVRAVGTKLVAEMCRTILGNKEAGIKGLHIYTLNLEKGARMLLDELQL
EGRREQIAPLPWRPSLTPHRRTESIRPIFWANRVQSYLSRTDDWDEFPNGRWGDSRSPAY
GDLDGYPVSIGISPAEAYSLWGHPTTFSDVAGLFARFCRGELLKLPWSSQPPASETSVIT
EQLAKMNELGFLTINSQPAVDGVRSDDKVHGWGPEGGYIYQKAYLEFFVSPELLSPLIRR
IERDPRITYYAVNRTGDLRTNTHSEGPNAVTWGVFPGKEIIQPTIVEAVSFIAWKDEAFE
LGLQWASLYPEDSPSRKLIEDIMNNSYLVNIVANDFKDGAGVFAPFMLDQKDNGNGHVAD
GVVAGLVNGVKDAVNGLLNGNGDSH
>A0A5C3PY81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polyporus arcularius HHB13444|TrEMBL
MKLSNKIAQRDARSLFYTFEFFPPKTDQGFENLVARIARMIALNPLAVSVTWGAGGTTKD
RTLDLAGLTQVEYGADTILHLTCTNMVQGTVDEALREAKERGIENILALRGDPPRGAEHW
IPTDSRFQHGVDLVRYIKSTPEFADFCVGVAAYPDGHPDRETDEDGELEHLKEKVDAGAD
FIITQLFYDVEVFLQWIQKVRAKGITVPIIPGIMPIQTYASFLRMTKLCGTRVPPKMMHD
LVPIRHDDQKVKEYGVKLAVDMIRQLQVGGIQGVHFCTLNLEKSVIRVLETLGLAGNVSQ
ATNKLIADVATLPERTMTPHAAADRATKELTSVPAPESDAGKGEINNAADWDDFPNGRFG
DFKSPAYGETDRWGSSAFQSKATTAPVSHWGNPKTVDDLTSLFLRYLHSKVTTTPFSSTP
LSPESLMIFPHLERLTSKGWWTVGSQPPVNGAPSTDEVVGWGPRGGYVYQKCFVEFFVEQ
KDVERIVKKVEEEGAGWISYFAGNAKGELLTNVPEGGRNAVTWGVFPGQEIAQTTIIEKE
SFLSWKDEAFSIWSEWASFYPPGSQERSLLEGISNDRWLVSLIHHDFLDPSALWTFLYKG
NNPLL
>A0A014F8L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 25977_10|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFM
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A495FKL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter oryzae|TrEMBL
MSPPSLIDTHPNLAGAAPVALSYELFPPRSAAAAESLWTTIGELEATDPDYVSVTYGASG
SNRSTAVELINRLVQETTLRPLAHLTCVGNSPQELADIIGELLDVGVRGILALRGDRPKD
GATPPPGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLLARSRRAGVTIPIIPGVMPLTSLRRLARLGELTGVE
PAPELIDRLAAADTDAERIRVGVGATVDLANAALDAGAPGIHLYTFNEHAAALDVLDKLA
LPRPRSGKNIGNRHGAGRASGLRRAASGQLAS
>D3SPS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermocrinis albus (strain DSM 14484 / JCM 11386 / HI 11/12)|TrEMBL
MKIRDLLRKGFSISFEFFPPKTEEGEEELFETIRNLQSINPTFVSVTYGAGGSTREKTRR
VVERIHRETSLTVMAHLTCIAHTEEELTEILRGYREIGIENILALRGDRPKDNSATEKRG
CQYAYQLVRLIRTKFGDHFSVGVASYPEGHPESPNLEWEVRYFKMKVEEGADFSITQMFF
DNSYYYRFVELCRKEGIDIPIIPGIMPITNFRQIQRFASMCGASIPHHVVQRLEPYAHLP
QETMKVGVELAIKQCEDLIENGVPGLHFYTLNKSKATLLIYDAIKDRVPTKI
>A0A2E1PD52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacteraceae bacterium|TrEMBL
MKDEIIKFVNNFTIELNPKVQKKITKIYINKKNRVFITYLPESEEKEIIEAIQFVNENGI
TPIPHLPARTMRDLKHVESFLQSIRKVSNTDEILVIGGGGNQIGKIASSLDIINSKLLEK
YDFKKINVAGHPEGSPDIDDETLKDFLLAKQKINDSTQLNIQIVTQFFFEANPFIEWDKM
LNDIGINLPVRVGFPGPATFKTLLNFGLMSGVGNSLNFLKKNSKKIGDLLIKTSNDELLI
KLIKSSKLSDKGRPNSFHCYPFGGFEKTCHWLSAIQNGEFAIENDKLVFHKKIF
>A0A7X2SBB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYREHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDNFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDRESIRK
FGEEVVTEMCEKLLAADAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A7C4Z5X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
PTQFAQKLGRGEFAISVEMDPPRGLSTHKLLAGASLLADAGADVINVADSPMARMRMSAW
AVCDLVQRKVGIESTLHFPTRGRNLLRVQGDLLAAHALGICNIFVVMGDPTSIGDYPEAM
DNYDLVPSGLIKLIKQGFNEGIDHSGTSIGQPTNFFVGAALNLYPPVLDNEIKNLHRKVK
AGADFFLTQPIYRPSDGVKLLEAYEAKHGRLEKPILVGILPLVSVRHANFLHHEVPGISI
PEETRKRIESAGDDGVKAGVEIAVELVEQVRPWAGGVYLMPQFHKYDMVAEIIEAVKIKS
>A0A7V1JKH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
HVPILVGIILLKSAGMARFMNSNVAGVNVPDGLIEEIGGVPRPDRPAKAVQIAARLIREM
KGMCQGVHIMTLGWERYVPQLLEEAGLEQRTRAVD
>A0A6M4PN72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. jing01|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCGTPVIPEVLPVTSVKMLERLPKLSNAHV
PDALKERILAAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A223UI19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella quasivariicola|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A350WRS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MENLERETMNLLEILNQKTVLADGAMGTMLHARGVGFDKCFDELNLTNPAAVADIHREYI
EAGAELIITNTFGANRYKLSKHGLQEDVAEINRAGVELAKRVVAASFRDVLIAGDVGPLG
VRIAPYGRVKLEEAREAFVEQIQALADAGADLIVIETMSDLYEIQEAIKAAKDVCPLPVI
ASVTFTRDDRTLLGDNPEKVAHRLVAAGADVIGVNCSGGPSQLLRILKQMRQAEPNAKFW
VKPNAGWPEQVSGRIMYPADADYFGEYALQFRDAGANIVGGCCGTTPQHIAAMKKSFELS
PAGAITEISIFPEDEITAEPEEQPTQLAQKLANGKFSICVEMDPPRGLSTHKLLAGASLL
HDSGADVINVADSPMARMRMSAWAVCDVVQRQVGVETTLHFPTRGRNLLRVQGDLLAAHA
LGIRNVFVVMGDPTSIGDYPEATDNYDLVPSGLIKLIKQGFNMGVDHSGTSIGQPTNFFV
GAALNLCPQDVETEVKNLHRKVKAGADFFLTQPIYRADDGPKLIEAYEAKHGKLNQPILA
GILPLVGLKHANFLHNEVPGIFIPDEARKRIEAAGENSAKVGVELAVELIQNIKGWASGI
YIMPQFHRYDMVSEIIVAVKE
>A0A800JNC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MTRIINRFGTGSPVFSFEFFPPKSDEGAEALMATVLDLQAAVNPDYVSVTYGAGGTTRER
TQQVVARIQNQIGLPAMAHLTCVAATKAEIDQVVDQLVADGIENILALRGDPPKDQENFQ
APEGGFAHASELIAHLAKRGGLCIGAAAYPESHPESSDADEDLHWTIHKVEQGASFLVTQ
MIFDNEHYFRFSDRLRGRGVQVPMVPGIMPITDVAQIDRFTKMCGVEIPGALSKRMHDHQ
DDPASVMAIGIEHAIEQCRELLARGAPGLHFYTLNRSLATRGILAALKG
>A0A838YPM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHITDIINKDRPTFSFEFFPPKSERASESLLETIKDLESLDPSYVSITYGAGGTTRERTH
DLVEKILETTSLTPIPHLTCVQHTEEEISNILKRYSDKGISNILALRGDTPKGDTQYDRS
NDSFYFARDLVEFISTFNTSTLGEESKSFGIGVAGFPEGHPETPNRIKEMDHLKAKVDSG
ADYICTQLFFDNHDFFDFRDRCELAGINVPIIAGIMPVTSISGMQRMADLAAGSRFPAKL
LKSIDRCNSDSDAVERVGIQYATEQCSDLLNHGVDGIHFYTLNKSKSTRGVFEALGINKT
SK
>A0A420PE16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum|TrEMBL
MSKKLIDEALSDAKALGIRNILALRGDPPRREEYRDPEDSEDDGGQDFNWAVDLVRYIRK
THGDYFCIGVAAYPEGHAEESHPLGQSLEHDLPYLVQKVQAGADFIQTQLFFDIEAYEHF
ETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRTTKLSHAKIPDHLLARLDAVKGDDERVK
MVGVDIVSELIDRIKAIKSKTPGPKGFHFYTLNLEKAVSFILERANLIPDPPENEEAIAV
DELAIPSLQINGSANMRSSSHSRSRQSRRHSSVASDPHNRVIVGDRPAIYPEWEATGQEA
GVRAEAINTRANTLAISEGEGVLGREATWDDFPNGRFGDARSPAYGEIDGYGVSLHMSVT
QAVKLWGYPKTRQDINDLFVKHIRGELSAIPWSEEELRAESSTIQPNLLQLNRKGWWTVA
SQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFFIPANEWDTLKAKLASSELQDSVCFYAS
NARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVFPGKEIITPTIIEEVSFRAWSEEAFGIW
GEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHDFVEKDALWQLLLS
>H3N5A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella michiganensis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRAIAQDYWNSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7X7MHU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oligosphaeraceae bacterium|TrEMBL
MSDERKQINLSFSGDNRFASSMMQGRFLYFLEIHSPLACQPAAAALALLKEKSRELAALP
QIFAFVVTDRLLSEDCHDPYLAAEAISTGSGKPVIISISGKGSSAERVKGILAEAKAQGL
RNFLAVSGDCPRQEQLADHPGRQHLDSLEILQTAGHFGPGLCLGAAVNPFKYTPEDQCLQ
YAKMVRKLRSGANYLVTQAGWDMKKAQELQWFLQKRAFAVMVVARVCLLSWEEAQQLADG
YRPGIYFSVPLGSALMQDAQGTQEEFQERQLRRVARQIVGYQKLGYGGVQLSGLRDPALL
QKLFGLIAQEESSNPDYDHWLKNWNDAYGKHNPAPGLGAHYLFRGLMQPGERDYAPEKHP
LAGTRLRRPARLDSWRASLGNLLLAGSRPPVWWRRILQLLCRLPEEELQRLRPCFYLDNS
SCPKGLRLGPCGGSRQDGRCEDGSQPCFFQRVMRLAAARNQFGTLEGDYDDTAKQQ
>A0A6G8YGP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas rhizophila|TrEMBL
MTAISFEFYPPKTDEQRAQLDRTASRLKAFAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGSREEIRELLKLYRAIGCRRIVALRGDLPSGMGHPGDLRYAAELISFI
RAEHGDAFRIEVGAYPETHPQANDALLDLKHFKAKIDAGADAAITQYFFNADAYFHFVDA
VRRLGVSVPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAESVRAFGAEVV
ASLCERLVAGGAPGLHFYTLNLAKPTTQVLKLLRG
>A0A1H8B0U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas marina|TrEMBL
MESQKKFSPTYSFELFPPQSELGVEKLRVARKKLAQLKPKFFSVTFGAGGSTRERTLETV
LEMQSEGYSVAPHISCIGSTRKNICSILETYQAAGVQQLVALRGDIPSGMAQAGEFRYAS
ELVKYIREAFGQAFHIEVAAYPECHPQARSYKADLENFHRKMEAGADSAITQYFYNADAY
FYFVESCESMGLSVPIVPGIMPINKFSQLVRFSDACGAEIPRWIRKKLEGYGDDTASIHA
FGLDVVTEMCERLLKEGAPGLHFYTMNSSELTSKIWQRLGI
>A0A4Y5YZB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteibacter pinisoli|TrEMBL
MPAISFEFFPPKTDEQRDQLDKAVEKLKGHAPDYVSVTFGAGGSTLSYTGDTVRRLRADH
GLSVAPHLSCMGGTKAEIRALLDEYKERGCRRIVALRGDLPSGMATPGDFRYAAELVAFI
REHSGDHFHIEVAAYPETHPQAENALVDLRHFKAKCDAGANGAITQYFFNSDAYFRFVDD
VTRLGVTVPIVPGIMPIANFSQLRRFSEQCGAEIPRWIVQRMRAHGDDAAAVRELGAEVV
AELCRRLLDGGAPGLHFYTINRARATTAVLERLA
>A0A0Q5VYZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter sp. Leaf380|TrEMBL
MTGTVRDLLAEGRPTWSFEFFPPKNEAAEGQLWTALRELERLRPSFVSVTYGAGGSNRDG
TIGVTERIATDTTMLPLAHLTAVDHTIGELRNVISRLAAAGVRNIMALRGDPPGLDPQAD
WVAHPQGLRYAAELVELIKDVGDFSVGVAAFPESHPRSPDAETDADMFVAKCRAGADFAI
TQMFFRVEDYLRLRDRVAARGCDVPVLAGVMPVTSTKQIARIVQLSGQAFPADLAERFAA
VDGETPEAKRAQRALGVEVATEMCRTLLAEGVPGIHFITMNRSTATREVYESLAELAPTA
>A0A2E8CQ06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHVQDIFAKRTPTFSFEFFPPKTEESSQALYETISELESHKPDFVSVTYGAGGSTRELTN
DLVVRIKNSTSLDPVPHLTCVCHCESDIESILARYAEEGVNNILALGGDPPRNLENYKKA
DDAFQQAADLVRFIKKFSEAGKHPDARGFGIGVAGFPEGHPATPNRLKEMDYLKAKVDEG
ADYIVTQLFFSNDDFHDFRDRCELAGIQIPIIAGIMPVTSTKGMERMADLAAGARFPAKL
LRILLGANDAETVEKVGIDYATEQCSDLLENQVSGIHFYTLNKSHATREIYASLGISPSP
SVNV
>A0A2E0PFW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRLIKDIYADKEALGKPTISFEFFPFKTPEGEVRFFDKTLPALMEARPDYASVTYGAGGS
TREKTLDIVEKIQGDFGLTTMAHLTCVKHTIDEINSILDDAKNRGIRNILALRGDPPPGE
NWSMTDGGFEYASDLVSYIKAQGDFGIAVAGFPEGHIDCKDGKEVDWQYLIKKIKCGADL
VITQMFFDNSDYFQLVDFLKEVGVNIPLLPGIIPVDNASQIKKFSALCGAKLPKKFTTRL
EELGDDSDAVREFGIEYASLQCQELLDNGAPGLHFYTLNKSKAVCGVLSNLNLA
>A0A3M6U6U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pocillopora damicornis|TrEMBL
MGFGRQDTAPAMELLQCVNNDQGSKSNTPSVPSSPLTLIEKINQKIVAKEKFFSLEFFPP
RTPNGAVNLIAKFDRISMGCPLFCDVTWHPAGDPGGDKETSSMTIASAALNYCGLETMLH
ISCANTVKDTVTKHLMKAKALGIRNILALRGDPPNGEEWQALDDGLAYGTDMVKHIRQEF
GDTFTICVAGYPNGHPDCPTYEEDLQHLKEKVDAGSDFIITQLFFENKTFFKFVKDCRDI
GITVPIIPGIMPIQGYASLRHLVKLSRLEVPQWIVDAIEPIKDDDEAIRKYGVELGIQMA
RELLESNDIPGLHFYTLNREVATREILTALGLWCQDPAASRPLPWKPSANKKRVCEDVRP
IFWASRPKSYMYRTSDWDEYPNGRWGNSSSPAFGDLSDHHLFYLRSKIKKEDLLKMWGGE
LASVEDVFEVFRCYISGEHNRNGVQVKSLPWNDDTIAPETAMIREKLEFLNSHGFLTINS
QPHVNAKPSSDPLVGWGGSGGYIYQKAYLEFFTCKENVDILLEVLKDYPQVNYHFVNREG
SVNVTNSDELSPIAVTWGVFPGKEIYQPTVVDPISFESWKDEAFDLWDQRWGRLYKEDSQ
SRRVIDDIYNNYYLVNLVDNDFIKGNCLWETLEKTVELREGTSKQMAAEA
>A0A4Q3T4H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MNLKEKLLRKQNGLLFYSFAPPKSKTEENKVRALAEKHIAHFSGLDIDGIILYDIQDEST
RTNEERIFPFMPTITPEVYTKTHLTGLDVPKIIYKSIANYTKEMFNDWLIENGDLEHVVF
VGASSQQQIENTGFTLTDAYQLKRDSFQNIILGGVTIPERHAKKGDEHLRLKMKQQQGCT
FFISQCVYNLSDTKNLLSDYYYDSIETGGEMSPIIFTLAPCGSLKTLEFMQWLGIQVPKW
LYNDLKNSKDILQASIDTSINIASEILNYSSSKNIPIGFNIESVSIRKEEINAANELLNE
VSKLVATDRSTLRNLINPQKIIQ
>A0A1G7T7L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limimonas halophila|TrEMBL
MAALTTEPVLAEMFRTGAKLPVSFEVFPPKSENARASLHYTATRLADADPGFFSVTSSPD
GSSRERTLAVARELAACTETPVKIHFTASGHTREQIDAHADRMWADGIRHVLALRGDRPA
DADRRGIPQAYEHADGLVAALKARHDFDVSVAAYPEKHPEAPSLDADIEHLKAKFDAGAD
RAICQFVFDAESYGRFRERAERHGIDKPLVPGVIVPTNWRRIRRFAVKAGASVPDWLDEL
FDGVEDEPEIAQLTAMATVQQQVRRLIAYGAPAIHFYTMNTWQIPLAAGHLMGRHVGDFL
GKTWCGAA
>A0A3L7UXN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MLIRDNYGPGKFGLSIEIFPPKTAAGDAALFESLDRLTAFQPGFVSCTYGAGGSTSKRTV
ELCVEIQKRYGLTATSHFTCVGATRDELLDWLKFARQSGLQNIMALRGDPPAGQTDFQPV
AGGLRNANQLVALIREHFPDMGIGVAGYPEKHPEASDADTDLNNLKRKVDAGADAIFTQL
FFVNDNFFRFRDRCEAAGIRIPIVPGIMPVTEFARIKRITSLCGAVFPTELASRLEAVQT
DEAAQFQIGVEWAIRQCRELVSRGVPGLHFYALNKSPACEAILNEIRD
>A0A2E5S8C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospiraceae bacterium|TrEMBL
MKKIAEILKEEAGKRPVFSFEFFPPKKPEGEQTLMNTIQRLKSLDPDFVSVTYGAGGSTR
EKTRQWVKDIQDKHDITAMAHYTCVGHGRDEILSNLKDLYSDGIRNIMALRGDPPKGEKN
FTPPEDGFAYGSELIEFIKSTGMDFSLGGGGYPETHQEAASADQDLQNLKKKVDAGAEFI
VTQLFFRNDHYFRYVKQCREAGISVPIIPGIMPITSFGQIQKFTEMAGCEIPNELTEDIK
ACGEDRGRLLEVSLGYSIRQCRDLLKGGAPGIHFYTLNQSQATSTILKAIN
>A0A2E6T643|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDIHAEKSTTGQPTVSLEFFPFKTQAGESKFFGKTLPALMTAKPDYASVTYGAGGS
TREKTLEIVDQIQKEFSLTTMAHLTCIKHTRDEIDAILDEVKKRGIQNILALRGDPSPGE
DWSRTEGGFEFASELVTHIRRHHDFGVAVAAFPEGHIDCIEGREVDWQHLVRKICCGADI
IITQMFFNNADYFRLADYLSEAGVKIPLFPGIIPVANAAQIRKFSTMCGAKLPEVFAARL
DELGDDSDATQEYGIEYATAQCRELLDRGAPGLHFYTLNKSRAVLKILTNLGLA
>A0A3B9W4T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coxiellaceae bacterium|TrEMBL
MAVPSLSFEFFPPQSDAALTQLGAVAQKLQVASPQFCSVTFGAGGSTQEATPRTVAELQS
QLGMPVVPHISCMAASSDELSVLLDQYQSIGVTQLVVLRGDRPSGVGLWQTEWTYASDLV
AFIQKRYSNTFSIRVAAYPESHPEASSMLADIHALKLKQDAGANSALTQYFFNADSFYHY
QALATQQGVTMPIIPGIMPIMDFEKLQRFSKRCEAEIPRWLVKQMESYSGDTASQYQLGL
DVVTHLCEQLLAMGVQHLHFYTLNQSQTVQAILQRLGVTSHQSAGTVTLSEGG
>A0A2D5EJL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTREEIGELLDVYKENGINRIVALRGDMPSGMGASGELRYAN
ELVEFIRQHSGDHFNLEVAAYPEFHPQARNAEXDLXNFARKVQAGANSAITQYFFNADSY
FYFIDRLEQMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCQKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A2E6NNK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MAAGRAWPSTGVVRRRRGIRMKFSEIYSSSGSPVISFEVFPPKTSRGMDSLRDVLARLVA
LEPRFMTVTYGAMGTTRSRTVEIASMIHNDLGIECACHLTCVGAPRDQIDGQLEHIHRQG
IENIVALRGDPPRGQDSFQAVKGGFSWANELVEHIRSKGLFDIAVGGYPEKHVEAPDLDT
DLDNLARKVKSGADVVITQLFYDNEPFFRFREEAWKRGVACPVVPGLLPIHSLAQVEKLA
SLCGAAIPAELQDRLVAAGDDPEAAAEVGAAWCIEQCAGLLAAGVPGIHYYVLNKAPVME
RVIAGLRQRELLI
>A0A4P5V203|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MRSGSRLEKALRAGRFAVTAELNPPDSADPQAVYDRAIVLASVCDGINATDASGANVHMS
SVGVCALLTRAGYEPILQVSCRDKNRIAIQGDLLGAAAMGVRNVLCLTGDGVGTGDHPEA
KPVFDIDSMQLLRMARMLRDEARFLSGRKLDAAPQLFLGAAANPFVPPYDYRPLHLGKKV
EAGADFVQTQYCFDVPRLRQFMATVRSLGLHQKVFILAGVGPLRSAKAAEWMRTHVPGVV
IPDEIIERLRKAAPGKQAAEGKRLCIEIIQQVREIEGISGVHVMAYRQEELVAEIIEEAG
LLPAPTRSRRAAASPAVRPRPAKPKLSQSTSQKQEHPN
>A0A2C6B1K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. polymorphum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNEKVGLEEVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHFTCIGSKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEPGD
FNYARDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A3D4EX56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MAILSSLRASRPTLSFEFFPPKNDLGSEELLETVNELGKLDPAFVSVTYGAGGTTRERTR
EVVQRIIQDTNVPTIPHLTCVGHTKSEISEILSQYSADQVGTILALRGDPPRDQPNYDRE
GDDF
>A0A2E8UNX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MRFIRDIFAEASAEGRPVVSCEFFPTKTPEGERSLLEKTIPRLKAAGPSFCSVTYGAGGS
TRDKTLDIVEAIQNEHELPAMAHLTCVGSTAEDIGGFLNEAQSRGIKNILALRGDPPAGE
N
>A0A522BEE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquabacterium sp|TrEMBL
MSTSARLPISLEFFPPKTPEGAAKLAAARQELYVLKPEFCSVTYGAGGTTQSGTLQTVQA
ILAEGVDAAPHFSCIGATEASVREQLAGFKAAGIRRIVALRGDLPSGYGSAMADPGPFRY
ASDLVAFIRRETGSHFTIEVAAYPEAHPQASNPQSDLRAFVTKVQAGADSAITQYFFNAD
AYYRFVEEARRAGADLPIVPGIMPITNSAQLIRFSDACGAEIPRWIRQRLLGYGEDLASI
QAFGLDVVSDLCERLRAAGAPGLHFYTMNQVRATRAICERLGW
>A0A367FWU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Subdoligranulum sp. APC924/74|TrEMBL
MQISQMFKRKPCVFSIECFPPKQTANFGKMKDTLRTMRTLNPDFISVTYGAGGSTGGVST
VEVAEFLKNDLNVEPLAHMICMGSDKAKAAQLLDQLNAAGVRNVLTLRGDRTPTRPESPD
FAHASDLAQFVWQTQPEFDIHAACYPEGHPEAATLAQDVANLRFKQEAGATHLLTQLFFD
NMHFYRFLNLARRAGITLPVSAGVMPIVKRSQIERTVALSSASLPSEFTRMISRYQDDPE
SLYAAGIDYAVQQLRDLIEGGADGVHLYAMNDAKVAAAVYEGIKDLL
>W8U9M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptoclostridium acidaminophilum DSM 3953|TrEMBL
MLISEKIKTNQPTVSFEIFPPKPGYPVDTIYDTIDSLSDLNPDFISVTYGAGGSTKDTTV
EISSLVEQKHNIPALAHLTCLTSTRDEIDGILDKLEANGVRNILALRGDVPQGSCAVDFS
DSMYSHSGDLVQHIKERGGFCIGGACYPEKHKESKNAWDDIVHLREKVDQGLDFLITQLF
FDNELFYGFVEKAGSMGVDVPILPGIMPVMNLKQVSKIVSLTGCSVPKKFLRIIEKYEHN
PEALKEAGMAYAASQIIDLLAWGVPGVHIYSMNKAEETRRIVNSISTIRGTQNRDCSKL
>A0A523PGG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MKIRDVYGRGRPVFSFEFFPPKTDKGEANLMATCADLQDAVQPDFVSVTYGAGGSTRDRT
HAIVSRVQKELRITAMAHQTCIASTRDEVRRSVESLEASGIENILALRGDPPEEDAGFEP
PAGGFAHATDLIEYLRESHDLSIGGAFYPEGHPESSSAEDDLHWTKRKLAAGADFLISQI
FFDNRYYFDFVDRAAAAGIDTPLVPGIMPITNVAQIQRFTKMCGATIPPELDARLRRHAD
DPAAVMATGVEHAITQCRELLERGAPGLHFYTLNKSHATRTILAAIRR
>A0A4Q3U7I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKITEHIKNANNKTLFSFELLPPIKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARVADTSFIPTKGGHCYATDLIEQIKNHNDGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNADFKFLKKKVDMGAEFIVTQMFFDNQRYFDFVKKCRENDINVPIIPGLKP
ISTLSQLNVLPKIFHIDLPDHLADTLSHAKSNAEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKQIAKAIF
>A0A0X8KET7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. SDLI1|TrEMBL
MGLLQDLEERILIGDGAMGTLLYSYGIDRCFEELNVSKPDEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVKIARASSDSAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALSSIADLGADITGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTDKEVKIRREEEVI
SVRDERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLNTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A5C9EWT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MTNRPAFSNLCKKIEEGHFTITGELEPKKILDLEEIIESAKEMKRTKKIAAANVTDGPQG
DAYMCSLVPSYKVQEKAGIEAVWQVTVRDRNRVALFGDVLGAAVMGLKNILVLTGDHTAL
GDHKKGRAVYDLDSTQFCDMLSKMIDEGTDLEGNELKGGKIEMNYGCVANPNSNPREPEI
MKVGRKVEQGVDFIQTQTAFDIDEAKDFLKDLEQFNVPVLLGIFPLKSYGIAWYFDNYIP
GVSVPKNLLKSLKTAEKENKGDKPAKYAAIDKINIEFFKPFIEEIKKTTKAAGIHCMAVE
YERLFDPLLKEFEEYTYL
>A0A7W4ILL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconacetobacter dulcium|TrEMBL
MNNTVKHRPAQALPGAFSPHALDMPPPALSFEFVPPRTDAQAHRLWQCIRRLAPLSPRFV
SVTCGAGGSPRASTRATVLRLKRETDLVPAAHLTCVGASREEIDEIAHSYWQAGVRHIVA
LRGDPPAGAADYTPHPGGYTHASDLVTGLRRIADFEISVAAYPETHPAAPSPAFDLDNLK
RKLDAGATRAITQYFFDAETCLRFLDRCMAAGITAPIVPGIMPVSNYDQVARFSALCGVT
VPAWLTHLFEDTAKTPDLRRIVASVVAVEQVRALQANGINEFHLSTLNHADLPFAIAHIL
GLRPTELSAPAESLTGNAL
>A0A8J6N649|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfaltia bathyphila|TrEMBL
MLVKEILNSTRPALSFEFFPPKTEAGFDKIFQAVSDLMQLKPSYASVTYGAGGSTRDYTA
NLVVRIQKETGLTVVSHLTCVGSTRDEIMSILEKSAESGIENILALRGDPPKGETVWKRP
ENGFDYAADLVSFINKNYPHICIGVAGFPEGHPLTPNRLKEMEYLKAKVDAGADYIVTQL
FFDNRDFYDFCERCELAGIHVPVIAGVMPITTRKGMIRMAQLAEGTRFPAGLLRSVARAE
NDEYFEEICVRWAAEQLRNLVYNNVRGIHLYTLNSSRAIFKIFKLLGVRDATQF
>A0A7X2RPA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas karstica|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKDDLRSLLTQYKSAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRSMGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A524FEX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MEGNQKYYSKLGEQLAKGEFILTGELEPEKTTDLSHTIHEAKEMSPYVVAANVTDSPLGI
VTINSMAATHVIQQESGLECIWQLTVRDVNKLGIAGMMMGAHALGIRNVLSLTGDHTALG
DMPESKPVFDLDSATLIRLVREMVDKGSINGYEIEAPPTLHVGGAANPNANPVEAEILKI
GRKAEAGAEFIQTQVVYDLDKTIEFLSEIKKYKVPVLLGIFPMKSYAIAKGFDEFVPGVS
VPKDILAQWKSIKKDIPDKKMQKEAYDQANYEFFKPFISELKKKGLLAGVHCMAVHYPRI
FPKLQEVIKG
>A0A4Q5WC32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MTFPISLEFFPPKTDEGAEKLRAARQKLYALQPEFCSVTFGAGGTTQDGTLQAVRAIMGE
GVPAAPHLSCIGQSRESIRERLAAYAAAGVQRIVALRGDLPSGYGAAGEFRHASDLVAFV
RAETGRQFRLEVAAYPEVHPQARSPEADLQAFIGKIEAGADAGITQYFFNADAYARFMDE
LGRRNVQVPVVPGIMPITSSTQLLRFSDACGAEIPRWIRLRLQAFGDDTASIKAFGLDVV
ARLCEQLRAAGAPGLHFYTMNQSVATLEICKRLAG
>A0A4S4BDZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus sp. Arct2-2|TrEMBL
MSQSFATGAAPQTRVSIELVPRSRSGLRAELEMVREHLPGIDTINIPDFPRFSTRSWMGC
AMARPHHRAIPHIRAVDINPREPLPMLDTLAAHGITEVLIITGDAPADMSAKVYDVDAVD
VIRRFRRELPDVRVYAGLDPYRQSFARERDYLERKLDAGAVGFFTQPFFDLRLMDAYADL
MPEGADVWWGATTVTTEQTLNYWRARNHAVFPRSFEPTLEWNRTFAAAALHFARERAQHV
YFMPVRADARDYLEGIV
>R1GCB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Botryosphaeria parva (strain UCR-NP2)|TrEMBL
MHISQKLQDGLKNGKPSFSFEFFPPKTAQGVQNLYDRMDRMHGLGPTFIDVTWGAGGRNS
TLTCEMVKVAQSVYGLETCMHLTCTDMEKTKLDEALREAYNAGCKNILALRGDPPREKEK
WEATAGGFRYAKDLVKYIRDTYGDHFDIGVAGYSEGCEDQEDPDLLLDHLKEKVDAGGTF
IVTQMFYDVDIFLDWVKKVRAKGIDVPIVPGIMPINTYAAFMRRATWTKCHVPPDWLKAL
DPIKNDDAEVREIGKHLIATMCRRLMEAGILHLHFYTMNLAQSTRMVLEELGLTPDIQSP
LEKPLPWRQSLAPGRREENVRPIFWRNRNRSYVVRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGTNEQNIKLWGMPKSVQDISNLFVRYMEGKLDSLPWSEQPITSEANVLKPDLVS
LNKRGLLTINSQPAVNSAKSSDPVYGWGPRNGYVYQKAYLEVLVSPELIAELLTRVERDP
EMTYYAVNKAGDLKTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEFFRLGEDW
AKCYTAASPSRYVIEDLMDTWYLVNIVHNDFHVPNGIFALFDGLEVQDIEKEPHGSAEAE
VNGSSKANGQSHTNGDKIPDTIVNGKSTSAVQNGTKN
>A0A4Q5VAC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
FIREETGRDFHIEVAAYPEVHPQARSAEADLQAFAAKVHAGADSAITQYFFSADAYFRFV
DESRKLGLDVPVVPGVMPIISSTQLMRFSDACGAEIPRWIRLRLLAYGDDIASIKAFGLD
VVTDLCVRLREGGAPALHFYTMNQSQATLGVLERLG
>A0A413KKB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM58-7XD|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A2T7AUA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter muytjensii|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPAGSGKPEMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVELKT
A
>A0A1G4IWN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea sp. CBS 6924|TrEMBL
MRVSEKLQKNLDSAEKSKATFSFEFFVPKTSQGVQNLYDRMDRMYQTRPQFIDITWNAGG
KLSQLSTDLVSTAQSVLGLETCMHLTCTNMPVELIDDALAKAYESGCQNILALRGDPPVT
TGEWKQCEGGFAYAKDLVKYIREKYGDHFDIGVAGYPEGHPEEEATPQLIDFLKEKVDAG
ANFIITQMFYDADIFIDWCRQLREAGIDVPIIPGIMPITTYAAFLRRANWCQIHVPDEFM
AQLDPVKEDDQAVREIGTKLLAKMCQKLLDSGYVTHLHMYTMNLEKASLMILDKLGLLAE
EEDIFRDEVVPMPWRKSLHPQRKNESVRPIFWQRRPYSYVARTSEWSADEFPNGRFGDSS
SPAFGDLDLLGSSLIRQSPQRALELWATPKTITDISNLVIGYLQGKIKCLPWCDVALNHE
VDSIVPQLLDLNEHQILTLNSQPRVNGLASSDSVIGWGPKNGYVFQKEYLEFLLPKSKLS
QFVEIIGNDTSLTYFAVDAADKLYSNHPDDTAANSVTWGIFPGREVLQPTIVEKVSFLAW
KEEFFHILEEWRLILSQDGHDDSAALLSTIIDDYALVNIVDNDFVAPGDRIYEHLKGLY
>A0A0M2KI08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia tracheiphila|TrEMBL
MSFYHANQREALNQNLAELNGQINVSFEFFPPGTSEMEHTLWASIDRLSSLKPKFVSVTY
GANSGERNRTHSIIKGIKERTGLEAAPHLTCVDATRNELRAIAEDYWRNGIRHIVALRGD
LSASSDKPTMYGVDLVALLREVGDFDISVAAYPEVHPEAKSAQSDLINLKRKIEAGANRA
ITQFFFDVEGYLRFRDRCVAAGIDVEIVPGILPVSNFRQLQRFASLTNVRVPGWMNSMFD
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPALCS
>A0A5Y3V3T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDASGDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQARKFADMTNVRIPSWMSQMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A258IR66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. 32-67-35|TrEMBL
MTLPPTLSGARRVIGPVARAGERGQSQGGGRPRVSFEFFPPKTLAMEESLWQAITRLAPL
DPAFVSVTYGAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASREEVDEVIREYWETGV
RHIVSLRGDPPPTEGGIGGVYAPRADGYANATELTRAVRAIAPFEVLVGVYPEKHPESPS
IEHDIDVLKAKVDAGASLAISQFFFDIDAFLRFNDKVRAAGITIPIVPGIMPVTNFNGLK
KMSQACQTAVPTWLANLFEGLDHDAETRRLIACSVASEMCAKLQEQGFEDFHFYTLNRAD
LVYAICRVLGVRERETASTEVAA
>A0A1G4JDP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachancea sp. CBS 6924|TrEMBL
MSTIKERYESSPGPFVSLEFFPPKTQSGKQNLMARMGRMTALNPLFLTVTWGAGGTTAKK
TLELAALAQRELNIPVCMHLTCTNTSKEVIDNALKEAHKADIRNILALRGDPPVGEDWDQ
GDAPSDFQHAVDLVRYIKKEYNNDFCIGVAAYPEGHCEGEADVMDHSPLRDLPFLKEKVD
AGADFVITQLFYDVEKFLAFESLFREQISNTIPLLPGLMPINSYQLFNRASKLSHASIPA
SILDRFPAEFRGDDNKVRSIGVDIISEIVETIYERTKGRVKGFHFYTLNLEKAVAQIVTT
SPCLAKIFEEEKDDDLVDGIEDIALEDADICDSANVKKRRRQSSTNNPDRTSNRVLIDDE
NKNIVKGREPSGAPSRKVVLSISQGSGSLGRDATWDEFTNGRFGDSRSPAFGEIDGYGPS
LKVSNQKAYKIWGQPQGFKDLQALFIRYLEGALEALPWSDLGLSPETALIQEELIQLNER
GYLTLASQPATNSTSSTDKIFGWGPRGGYIYQKSFVEMFVHKEQWNNVLKPKLEPLSPNV
SFYVGDSEDAFYSSLETNGSSVVTWGVFPNSEILQTTIVEEESFKAWRDEAFSIWLEWSK
LFPRGSATNSLLRQVRKDYYLVSIVHHDFSQCDALWDLLLT
>B7RV76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine gamma proteobacterium HTCC2148|TrEMBL
MRFEDEPAAGENLPILPGHVSPGRLERVLRAGVFAVTTEIAPPDSADPLEVYDRASAFDG
YVDAINATDGSGAHCHMSSVSMCALLTRRGYSTVMQVSCRDKNRIAIQGDVLGGSAMGVS
NILCLTGDGVQSGDHPEAKPVFDMDCMTSLEMLRGMRDESRFLSGRKLTHPPQVFLGAAI
NPFAPPYDFRPLRLAKKVAAGAQFVQGQYCFDIEMFKEYMSRVRDMGLHEKVFILPGVGP
LASAKSAEWIRSNVAGVHIPDAVIKRLKGAENQAQEGTNVCIDMINQVREIEGVAGVHIM
AYRQEHRVSEIVEKTGVLGDRRPWEPRIYQDTFGQAEQTADSKK
>A0A7V4JL43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MAKIIDKLKTASRTLFSFELLPPLKGHSIDEIYRSIDPLMEFNPVNINMTYHQPEVVYVP
ASDGLLEKKVVRKRPGTLALVAAIKFRYNVTVVPHVICAGHTKEEIEDILIDLNFLEIKD
VLLLRGDAPKGQKVFIPEKGGHAHTVDLVKQVKNMNNGIYLDPSLKNPVKTDFCIGVAGY
PEKHIEAPNKETDLKYLKEKVEAGADYIVTQLFYDNKKFFSFVEECRAMGIHVPIVPGIK
PTTLLSDLRLLPQIFAVSMPQELVSELEKCKTNQEVREVGVEWAIHQCRELIRYGVPAIH
FYTYGMTENVARIARAVF
>A0A7X9KR41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVIDHINQAKDTLISFEILPPLKGKGIQSLYKLMDELMEHKPSFINVTYHRSEHVFKKT
ATGDFKKVIVRKRPGTESICAAIMNRYNVDTVPHLICGGFDINETEDALINLNYLGIDNV
LVLRGDAAKNETNFEPEPGGHKYAIDLLRQVGNLNAGVYLEEDLKHSIKTKFCIGVAGYP
EKHFEAPNMETDLQYLKQKVDAGADYIVTQMFFDNTKYFAFVKSCRDMGINVPIIPGLKP
VYSVKQLTVLPKVFHIDLPTELSGEMIKCKSDEEVEKLGTEWLYHQSVELKKSGVPVLHY
YTIGKPGVVCDVVKRLQ
>A0A7Y5MGH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MHIADILKQPAPHFSFEFFPPKTEEASKVLFDSINDLTPLKPSYVSVTYGAGGSTRQFTH
DLVVRLQKETRLNIVSHLTCVNATKDEIHDILAKYDENGIRNIMALRGDPPKGEVEFRKT
ENGFAYAAELVSYIKKNFPHMGVGVAGFPEGHPSTPNRLKEIDNLKAKVDAGADYICTQL
FFDNRDFYDFCERCEIAGIKVPIIAGIMPVTTRKGFARMAEFALGARFPAKLLRAVSRAQ
DDEYVEKVGIHWATEQVRDLIDRNVAGIHFYTLNRSKPTLKIYDSLGITSSDSLRRAPVP
LA
>A0A1V3U162|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia meningoseptica|TrEMBL
MKVTEHITQSKGKTLLSFEIIPPQKGHGIEDLYTNIDPLMDFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTQEETEYLLVDCLYLGIDN
VMALRGDAMKGEKYFAPTKGGNQYASDLVSQINDLGKGKFLHGEISGGDTNNRFCIGVAG
YPEKHLEAPSLQYDLKMLKQKVDLGADYVVTQMFLDNQKYFEFVKQAREAGIEVPIIPGI
KPLAIKKHLQLLPQVFKIDLPEDLVNAVAQCKNNEEVKQVGIEWCIQQCKELLDFGVPAL
HFYTMGKSDNIQKIVGEFF
>A0A839XRB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prauserella sediminis|TrEMBL
MSARIPTSGGASSSTQPSARHRAALAGTLRNASYEVLPFRSTEDKVLAHVPLDVPLTVTA
TEAKGIETTVELAVRLSKNGYRIAPHLPARLIRDRAELDDIAAQLLESGIERIFAIGGDA
AEPAGEFADAESLLIALAEGGHAFRNVGIAGYPEGHGKLSDAVIDEALRAKTGHAHEIIT
QLCFNPDTTIGWARGLHAEGIRTPIRVGVPGSINRQKLIRVSASLGLGQSARFLAKQSAM
LWRFFLPNGYRPDKLITKLADQIGRPDNELAGIHVFTFNDLASTERWRQRWLDRLS
>A0A7W1EV32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKLTQKLSQSKKPLFSIEILPPLKGKSIQSIYDGIDPLMEFKPAFVDVTYHREEYIYKKR
DGGYLEKVSIRKRPGTVGICAAIMNKYNVEAVPHIICGGFTKEETENALIDLQFLGIDNV
LALRGDSIKTEPAFVPEPGGHAYALDLVKQITEMNRAQYLDEEMKDAAPTDFCIGIAGYP
EKHFEAPNMISDLKYLKAKVEAGAEYVVTQMFFDNKKYFDFVKLCRDNGITVPIIPGLKI
LSTKKQITTLPKIFHIDIPQPFYEELEKCKDDKAVKEVGIQWCIEQSKELIKANVPCLHF
YTMGTSEATKKVAKEVF
>A0A855K401|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MPBC4-3|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLTSYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLTQYRQAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1H9BC65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas lutea|TrEMBL
MTRTTPNVSFEFFPTKTEAGHEKLLNTARQLAGYSPEFFSCTYGAGGSTRDRTLNTVLQL
DSEIRIPTAPHLSCVGDSKAELRDLLIRYREAGITRIVALRGDLPSGMGISGGELRYANE
LVSFIREETGDHFHIEVAAYPEVHPQARNFEADLANFVRKIKAGANGAITQYFFNADSYF
HFVDRACKLGADVPIIPGIMPITNYSSLARFSEACGAEIPRWIRKQLEAYADDVKSIQAF
GQEIVTDMCERLLAGGAPALHFYTLNQAEPSLAIWNNLGFKS
>A0A3D0QA47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MENSVKLDFRERLRRGPILCDGAMGTLLDLYEYSDRPHEINNIKNPDIVARVHQEYIDAG
AEIIETNTFSANRFRLSQFHLQDRLKEINKAAVEIARRVAGDRVYVAGSVGPTGKLLEPI
GKIKLLEARAAFKEQIEILLEGGVDLLILETFVSLNELDEAITAAKELTKLPIVAQKAFP
EDGSILSGTFPLEVVEHLLSRGVDVVGANCTVGPQRMFSIIRTMYKDGVILSAQPAAGIP
TLQDGRSVYHTTPEYLATYARELIQSGVTMIGACCGSTPAHIRAMRKVMDELASQPVASV
AAPKIGSPAGEKIAPVAQPEQAPDNRSNFARNVGKKFLVTAELDVPRGVDMSSVIEGARY
LHRHGIDAINITDGARARLRMSSVALSTMMQQEVGMEAMTHFTARDRNLIGLQSELLGAH
ALGLRNVLCITGDPTSIGDYPHATSVFDVDSIGLIRAVRAMNEGRDLMGNTIIQKTSFLI
ACAANPKADDMDREVDRLEKKIEAGAEIVFTQPIYEMQTLEQFIKRCEEWRRPVMLGLLP
LRSYRHAEFLHNEIPGMVIPESIREALRRAGDRAAGVGVQLTQEFLKEARHLVAGAYLMP
PFKRYDVVPQVLEAVR
>A0A7Y8TFK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVIDHIKNAERTLFTLELLPPLKGETIETIYQAIDPLVGFSPSYINVTYHREEVVYKPQ
ANGLLERQVVRKRPSNVAIASAIRFKYGIDVVPHMICGGFSPSETEDGLIDLHFLGIDNV
LALRGDAPKLDKTFVASKGGHVHATDLVKQISRLNKGIYLEEELLQPSPTNFCVGVAGYP
EKHSESPNLDTDLRYLKEKVDAGADYIVTQLFYDNSKFFAFVEKCRQIGIMVPIIPGIKP
ISVKNHLSILPRTFNIDIPEDLVKAVNECKDNSMVREVGVEWAIQQTKELMQFGVPAIHF
YTMGKPDNICKIAKAIF
>A0A7Y2BRP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MAPLQKPKPYDPLRSKLPEPPAGHKSSSMLETTLRRGWFAVTAELNPPDSADPRDVLAAA
EPLRDVADAINATDASGANCHMSSMGICSILSRAGLGIVLQISCRDRNRIAIQGDVLGAA
AMGVSNILCLTGDGVGVGDQPGAKPVFDLDCMSLLRTLKTMRDDETFLSGRKLTSPPKLF
LGAAANPCIPPLEWRADRLAKKVAAGADFIQTNYVYDIEIFKQYMQRVRDMGLDEKTFIM
AGVGPL
>A0A662CVB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
GEDGLTRYGVDLEDVTNALTKSEASVIGLNCTVGPKPMLDFVEQMGRLTDKPLCLMPNAG
RPQFTDGRMIYMSTPEYFSVYTKRFIERGVRVLGGCCGTTPEHIGKMANALAMKQTRIQH
SINIGVKPVSEEPLPEPVPVAEKSKLSAKMLSGQQVVLVEMVPPRSTDITKPLEGARLLQ
EHRVDAINIPDGPRATARMTGLALAVLLQNQVDIETVLHYTCRDRNLLGMQSDLLGATAM
GIRNILAITGDPPMIGDYPQATAVFDIDSIGLVHLINNLNHGIDVGEKRIGDPTSFFAGV
GVDPNSVNPENELHRLQLKKEAGAEYIITQPVFDVDSLEKFLEKADLGSLSLIAGIWPLV
SLRNAEFMKNEVPGVYVPDEVISRIAKYETKDDQLKAGIEIAQGMIDRVAGFVQGIQVSA
PFGRYKLAVEVAGAMLKRNK
>A0A7W2BFG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MVIKRITHKLPDISAAPIIPASIEASPAQVLGATDLAGLFPQGVRVYLTDTGAASQERLV
EAAAHLRDFGYEPVPHLAARRIPSSAAFVEQVRRLAGEAGVTDVLVVGGGVERPVGPFAS
SMDMLSTGIFDRCGINQIAIAGHPEGSPDFNDDTAMAALRLKRDFAERSDAAMRIVTQFG
FDPARFIAWAEGLIASGIELPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LARGHSPESIVGPIERHWQANPQGPIRQIHVFPFGGLQNSADWLVKRGSWQTGAADRSAS
PDSRAG
>A0A7W6WL78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseospira goensis|TrEMBL
MKIDPRTVAEGKTALPLCGRLPDNVKVSFEFFPPKTEKMAESLWAAVKRLEPLGPQFVSV
TYGAGGSTRDRTHETVARIARETSLTAAAHLTCVNATREEVDAVARRYWDAGIRHVVALR
GDAPDSDGVYRPTPGGYAFAADLVEGLKRVADFEISVAAYPEVHPEAASPDADLDALKRK
IDAGATRAITQFFFDVDVFNRFRDRAAAAGITVPIVPGILPVANFATVTRFAGMCGAHVP
RWMHETFEGLDDDPETRKLVAGMVAAEQCRALAAAGADTFHFYTLNRADLTVAICHTLGV
RPPVEEPAPA
>A0A6H2HD93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas vacuolata|TrEMBL
MTLPISFEFFPTKTEEGAAKLRLVRQELYALKPEFCSVTFGAGGSTQSGTFAAVGEILAE
GVDAASHFSCVGATKSLVREQLATLRAMGVKRLVALRGDLPSGYGAAGEFHYASDLVEFI
RAETGDAFHIEVAAYPEIHPQAKSAEADLQAFATKVKAGANSAITQYFFNSDAYFRFVDD
AFALGVDVPVVPGIMPISNSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVI
TDLCDQLSMAGVPGIHFYSMNQSAATLEICRRLHF
>A0A6N6KGW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEYFEKANGQTLASFEVLPPLKGGSMQAIFDSLDPLMEFKPPFIDVTYHREDFIYKK
RSSGYFEKVAIRKRPGTVGICAAIMHRYGVDAVPHLICGGFTKEDTENALIDLNFLNINN
VLALRGDARQFDGKFIPEEDGHHFAIDLIHQIVDMNNGKYLHEDIENGSKTDFCIGVAGY
PEKHFESPNLDMDLQYTKAKIDAGAEYIVTQMFYDNQKYFDYVKKCREVGIDVPIIPGLK
PITKKYQLNSLPRLFHIDMPDDLVKELSLAKDAEARTQVGIEWSIQQSKELKEFGVPCLH
YYTMGDSDIIHSIMEKVF
>A0A661XT80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
TNFCIGVAGYPEKHFEAINKKTDLKYLKQKVDAGAEYIITQIFYDNQKYFDFVKDCRAAG
IDVPIIPGIKPITKTSHIKFIPKTFHIDFPDEFGMDLIDCKTDEEVSEVGTSWAIQQAKE
LINFGVPVIHFYTMGRSQAVRKVAKEIF
>A0A2E4Z4V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MPTRFDSPTLAGRIKVSFEFFPPKNGXMEGQLWESISRLAPFNPDFVSVTYGAGGSTKQP
TLNTISRIIGETDLAPAAHLTCVDATREDVDQVALEFAQSGVKHFVALRGDPSEGVGAKY
RPHPGGYENSAALVRGLRELGDFEISVAAYPEKHPESPDFALDIDLLKRKVDAGATRALT
QFFYDNDAYERYVERVRKAGIFIPIVPGIMPIHNFAQVARFAXMCGASVPXLLARRFEGL
ENDXETRAMVATAVAAEQVYDLVERGVDEFHFYTMNRAKLVYAICHLLGLRGNGNGSNGN
GIHVAA
>A0A2A5FQW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSIIANLRQHKKRAKRISFEFFPAKSDKGEVQLWESINRLGLFNPDFVSVTYGAGGSTRE
RTHRTVADLAKKTSYRPAAHLTCVSASRDEVDAVVEGYAAAGVKHIVALRGDPQDGSNVF
RAHPQGYQNAADLVAGIAKRGDFEITVAAYPERHPDSPSWDHELDNLKRKVDAGASRAIT
QFFFDNDVYEAFVERARAAGISIPIIPGLLPVYKFAQLKSFAAMCGATLPHWLARAFQGL
DDDLETQRMVSTAILAEQVFDLAERGVEDIHFYTLNRSEIVFAVCHLMGLGPELQAVNLS
VEAA
>A0A0J8G6S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fildesensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A5N6EGZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus novoparasiticus|TrEMBL
MHIKEKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAAEGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLETL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIKDLSRLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLIE
LNHRGILTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNE
DLTYHAVSKNGELRTNTNDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDSWYLVNIVNNDFHNTYDLFELFKDLNVRDFDVEVAADNADLK
SQENETAETAAN
>A0A3D3ATS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQHFVDKVNAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>D4H136|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denitrovibrio acetiphilus (strain DSM 12809 / NBRC 114555 / N2460)|TrEMBL
MKISEILKDKRSVSFEFFPPKKQESEQVLFETIKKLRRYNPEFVSVTYGAGGSTTEKTLE
WTKRMKEDHDYSVMMHFTCIGADAAVIDSATQSLKESRVDNILALRGDIPAGTTEFKPTK
DFQYAADLVRYIRKTTGDHFSIGVAGYPEKHPEAGSMAEDIDNLKRKVDEGADFIITQLF
FDNFYFYNYLDKVRKAGINIPVVAGIMPLVNLSQAVKFTDMCGASIPKPLLEKMEDKSLK
DQFEIGLDYAVKQCGGLWESGAEGLHFYTLNKHGVTEEILKRIF
>A0A0Q0E3W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. viburni|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VAFIREETDSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A4V0X4F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVIDHINQAKDTLISFEVLPPLKGKGIEALYKHLDPLMVFNPSFINVTYHRSEHVFKKK
ADGNFEKVVVRKRPGTESICAAIMNKYNVDTVPHLICGGFSVNDTEDALINLNYLGIDNV
LVLRGDAAKNESAFEPEPGGHKYAVDLLRQVVSLNDGIYLEEELRDTQKTKFCIGVAGYP
EKHFEAPNKETDLLHLKQKVDTGADYIITQMFFDNAKYHAFVKDCREIGITVPIIPGLKP
IYTKKQLTILPKTFHIDLPTELSNEVLRCKTDLDVEKVGREWLLMQSRELKKAGVPVLHY
YTLGRPLLVADVVKDI
>A0A3D0QFD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MTLREKIESNQFVVCGEVGPPQSCDGDVIREKARHFKGYVDAVNITDNQTAVVRMSSIAS
AKILLDEGIEPIMQMTCRDRNRLAIQSDLLGAAALGIRNVLCLTGDHQKFGDQPEARGVF
DLDSIQLLATVAAMNKGLLLSGTEMKKASAFLIGAAANPFAAPFEMRLIRLQKKVQAGAH
FIQTQPVFDLEIFARWMGRVVDMGLHEKTAILAGVLPVKSVKTLLWMREKVPGVRIRDEY
VRRMTETRDPEEEGVKMAVEIIQTLRTIKGVRGIHLMPALWESITPTIIKEARLSAEELE
KESH
>A0A143XWN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. CHKCI003|TrEMBL
MNVVKIIHDALAEGRTRFAFELLPPLKGEGKHGVYDAIDPLAEFDPAYINVTFHREGIKQ
TVRPDGSVERHVVRRRPGTVGISAAIRRKYGVETVPHLICGGLSRYDIEDALIDMDFLGL
HNVLALRGDKSKNEERFTPHPQGHAHAADLVRQIAAMNRGEFVDGEAEACHHSKFSIGVA
GYPEAHFESPDAAADLMRLREKVEAGAEYVVTQMCFDNGRFFDFVRRCREAGITVPIIPG
LKPLSTLRHLTVLPDVFGVSIPDALRREAEAHPAGVREVGIEWAAAQARELKAAGVPVIH
FYTMGRTDNIRRIAQTVF
>A0A2E1J5C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MTSISLEFFPPKXAETEAKLWDVINELAVIRPDFVSITYGAGGSTRXRTHKCVKHLVTKT
DLKPAAHLTCVAASKSEVDEVIEDYAVAGVKHIVALXGDMPDMEAFSPHPDGYRGSVELV
DALSRRGGFDVTVSAYPEKHPESGDMQTDIDLLKAKIDAGATRAITQFVFDTEHHYRFRD
VLADNQINIPVIPGIMPTTNFKGVLRMSEACGASVPDWMKSKFEGLDDDLESRRALAIEV
ATEQCRDLIKSGFENLHFYTLNQATVTQAVCNALSLENVGVQ
>A0A3D5CZU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilus sp|TrEMBL
MNHKTSYSFEFFPPKTAEGMANLRNVRDELAAFSPEFFSVTFGAGGSTRDRTMDSVLEIQ
AAGHGAAPHISCISSSKEEIRELLQAYQAKGIKRLVTLRGDIPSGEVSAGDFKYANELVS
FIRAETGDWFHLEVAAYPEFHPEAGSAQKDLENFKRKMDAGADSAITQYFYNVDAYFRFV
EAAQKMGVTAPIIPGIMPIYNYTQLARFSNVCGAEIPRWLRLRLEAYGDDLASLRAFGAD
VVTDICARLIASGVDKMHFYTLNQAGIIGQIIRQL
>R6GHI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. CAG:52|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMFGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLEEGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMVKFMNNNVAGIHVPDEMIEE
LKADKERTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A0L0W771|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gottschalkia purinilytica|TrEMBL
MFIKDLYDKKKPIVSFEIFPPKRDYDIDTVYETIQDLRDLNPDYISVTYGAGGVGSSDKT
LEIASLVKNKYGIEALAHLTCITSDKVKTKAVIEDLKKHNIENILALRGDIPEGFELEDD
RDYSYAKDLIKDIKEIGGFCIGAAAYPEGHIECDKLNDSLIHLKEKVDAGAEFLITQLFF
DNDIFYKFLEKAEKHSINVPIVAGVMPILSRSQVEKMIFMCGASLPSRIIKILNKYEGDS
ESLKKAGIEHAARQIDDLIRNGIDGVHIYTMNQPEIARENVRRIESLKEQLLKQSI
>A0A1A9FI28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lelliottia amnigena|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLREVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMQKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A329RTN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora cactorum|TrEMBL
MKIIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLXXXXLFCDMTWGA
GGSSAQLTLELSANAQKLSGLEMLMHMTCTNMAEADIKKALDQAKDAGIQNILALRGDPV
RGATSFDECDRGFSHAVDLVRYIREKYGDHFCIGVAGYPEGHVEIKDKKADIQYLKEKVD
AGADFVITQLFYDVQVFVDFVKECRTVGITVPIIPGIMPIQNYGGFERMTSFCNTYVPEE
VRKALEPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLS
SRVPRRELPWQTSTLSKRASESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGE
LTESHFAPSNTSTPRERRAMWGEAPASKEDVRRTFVQYVRGEISSLPWCDAALHAETSTV
QQELAAANSAGFLTINSQPRVNGALSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIID
NAAKKPSVQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFT
LWLKLWASLYEQGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSPATSP
>F6D9P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomicrospira cyclica (strain DSM 14477 / JCM 11371 / ALM1)|TrEMBL
MKSQQQYPQGFSLECFPPRTAEGSEKLNQVIDDLSVLNPEYISVTYGAGGTTQEKTLETV
THIQQSTRLDAVPHLTCIGATKDSIRALLKIYQDLGIKRIVALRGDMPSGMMDPGEFKYA
ADLVAFIRQETGNQFILEVAAYPETHPQARNCDQGIKHFKHKVDQGADAAITQYFFNADS
YFYFIDSCEKAGIDLPIVPGIMPITNYEQLIRFSLMCGAEVPRWLKCRLESFDEDTASLR
AFGQEYVTRLCQRLLDNGAPGLHFYSMNKTQPTLDIVRDLNWRNDNLQM
>A0A6L8UUZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus silvestris|TrEMBL
MKLDLRSTLQQDILTGDGAMGTYLYQMGFPVGISYEELNLLRPETVAEVHRRYFEAGARL
IETNTFSANREKLSKYGLEGDVEAINRAGVELARRVVGNEAYVVGAIGSIRAGKRKNVRT
ADVEESLHEQISILLDSSVDGLMLETFYDLEELQLALRIIRSMSDLPVICQFANEGTGST
QDGVPLQEAFLRLRDEGADVIGFNCRVGPNGILRSMEKLTPLAGVPFSAFPNAGLPDYVD
GQYTYAATPQYFAESALRFADLGARIIGGCCGTTPEHIAAVAKALQDYVPAAPGTAGPAR
AVRVLEPAPAKPAPPAGKPSLLEIVKQRKTVIVELDPPRDLDIDKFMQGSKALQDANVDA
ITMADNSLAVTRMSNLALGHLVQDKLGARPLIHIACRDRNMIGTQSHLMGLHALGIDHVL
AVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFVVGAAFNPNV
KHLDKAVQRLERKIEAGADYIMTQPVYDAKLIEQIYEATKHLNIPVFIGIAPLASGGNAE
YLHNEVPGIRLSDEVRARMSGLKGPEGRAMGVEIAKELLDAAMPYFNGIYLMTPFLAYEM
CVDLTKYVWEKSNRHDFHLYPLSK
>A0A6I5G521|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8380|TrEMBL
MASGTASTWTSEHPTVAEVLASGKRSYSFEFWAPKTPKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRTGTVRATQAIAENTTLVPVAHLTAVEHSVAELRHMIGQYADGGVRNILAVR
GDPPGDPLGDWVAREDGLTYAAELVRLIKESGNFCVGVAAFPDMHPRSENWDSDVRYFVD
KCRAGADYAITQMFFDPASYLRLRDRLSAAGCETPVIPEVMPVTSVRQLERLSRLSTAVF
PETVKERMLAAKDDPAAVRSLGIEFATEFCARLLAEDVPGLHFITLNNSTATLEIHENLG
LPHHRP
>A0A829NA64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNJC398B00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A6N4SQU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cytophaga hutchinsonii (strain ATCC 33406 / DSM 1761 / CIP 103989 / NBRC 15051 / NCIMB 9469 / D465)|TrEMBL
MKVTEHIAQAKGKTLFSIEILPPLKGQNIQSIFDAIDPLMEFKPPFIDVTYHREDYQIKE
RADGTKEKITVRKRPGTVGICAAIMNRFKVDAVPHLICGGFNRQETEDALIDLQFLGIDN
VLALRGDPIKFEGSFVAKPGGYNYACELVSQINDMNKGIYVEEDLLNPAPTNFCIGVAAY
PEMHMDAASMEVDMRNLKHKVACGSDYIVTQMFFDNKKYLDFVANCRANGITIPIIPGIK
PLTTKKQLQILPKIFHLVIPEDLVKEVEKCKDDEQVRQVGIEWAIQQSKELMQAGTPVLH
YYSMGKSDTVKSIASNVF
>A0A6J4YEI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis Delta 1 endosymbiont|TrEMBL
MSLNTASKLEKILSEGHYAVTSECGPPRGSKPEPILEKAELIKDHVDVINITDNQTSMTR
LCSLAACIRLKLNGLEPVLQMVTRDRNRIALQSDILGAASFDINNILCLSGDHQSFGDNP
KGQNVHDIDSMQLIQMVRLMRDEAKFLGGDDLDQPVKMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNLDKFEKWMEGVRERGLHEKCYILAGLTPMKSVGMAKYMQKRVPG
MDVPDEVIKRLQGVEKGKQAAEGIKMCIESIERLKECEGVKGFHIMAIEWEEKVPEIVEA
AGLYPRPSVN
>A0A0D7NN42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. LTSP885|TrEMBL
MTETVSPVSNGHRAPRTPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS
TRERTHSTITRILRETDLLPAAHLTCVGAARGEIDEIVDRYHEVGVRHIVALRGDPPGGI
GTAYATHPDGYQNSAELVAGIRKRHSDIEVSVSAYPEKHPEAADFDIDIDLLKAKVDAGA
TRAITQVFFDNDLYYRYLDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFDGLDNDAETRKLVAATVAAGQVQKLFKRGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A1J5GT22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium CG2_30_33_13|TrEMBL
MIHHIQNKIYHIEVLPPKQDSEKLEKDLEIFSNKYLRVMDSSYCTCITDNTMGLLSFQGT
EIIEELDLPVMSEQVMIHLNTFHTKDDLDNILDICKSKGIRYLLIITGDGSERLPKLQPS
DVGATDVESVTSVELLKYINHEYPDTFVLGAAFNPYEPEEHEFEKMKRKMKAGATYIITQ
PLIERNEVVDRLLEKYPEIPVIIGTWMSRKLHLLSEAVGYEIPGNAEYDPISTLKMLHKL
YPGCGVYLSLLGFKTQYDLIKDIWV
>A0A495INW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter nauticus|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTREEIGELLDVYKENGINRIVALRGDMPSGMGASGELRYAN
ELVEFIRQHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEQMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCQKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A0Q6WUK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Root369|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPMAEWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWEGDVTHFVD
KCRAGADYAITQMFFQPESYLRLRDRVHAAGCETPVIPEIMPVTSVRMLERLPQLSNAII
PSVLKERILTAKDDPTAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A4P7PTL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sangjuense|TrEMBL
MKVTQHIQNANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LPSGLLQKKIVKKRPGTVGICAGVQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDALKTETYFHPEKEGNEYATDLVLQISNLNNGIYLDEDLKNSAQTNFCIGVAGY
PEKHMEAPSLDSDIHFLKQKIKNGAEYIITQMFFDNKKFFDFVDKCRASGITIPIIPGLK
PIATKKQLNLIPHRFSVEMPDDLIMAVVKAKDNDAVKQIGIEWCTQQSKELVAAGIPVLH
YYSMGRAENIKAIAKEVF
>A0A1S2A1I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cylindrospermopsis raciborskii MVCC14|TrEMBL
MQENHTTIHNGNSLTSFREAVQAGEFLITAEVAPPKGGDISHTIAMSATLKGRVHAVNIT
DGSRAVLGMSPLAVCAILCQHGIEPICQVACRDRNRIGLQADLMGAHALGIRNILALTGD
PVKAGDHPDARAVFDLESVRLLELITNMNQGLDFNHRTLVDGGLDLFAGAAVDPQSKSWS
GLQSRFERKVQAGAQFFQSQLITDFEKLEKFMDKIASSYNKPVLAGIFLLKSAKNAQFIN
KMVPGVNIPDHIIQRLAKAKYPLEEGMKIASEQVKMAKDLCQGVHIMAVKKEEAIAPILD
LAGVSR
>A0A4R5UMD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium deserti|TrEMBL
MEAKTAAPQPFALSLEFFPPKSDEMEAQLWEAVEQLSPWQPDFVSVTYGAGGSTQEPTLA
AVRRMIGDARLATAAHLTCVDASKQEVKAVVEEYRAAGVRRIVALRGDPTTGLGTAYLPH
PEGFSDTADLVRTLVAYGDFDVSVSAYPEKHPESPDIAADINTLKRKADAGATRALTQLF
FDNDIFERYLEKVRAAGIAIPIVPGIMPIQNLTQMKRFARRCGASVPAFLDDRFEGLDDK
PEERAKVAADVAAEQIEDLMRRGLDEFHIYTMNRAPLVSAVLEQLGRCRRQAASVGAAA
>A0A542YUY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ornithinicoccus hortensis|TrEMBL
MSAEPIVPVPDAALLALRSPRFEMVPMRGLEEALDHLPPGATVPVTCSPTRGLDATLPVV
TELVRRGHRPVPHLAARMVRDTAQLRGVVAELDRLGVRDVFVVAGDAATPAGPFEGAADL
LRELHRIGHPFLEVGVTGYPESHSFIPDEATVSAMADKAPYATYLVSQICYDADTVVGWV
RAVRDRGIMLPVHLGIPGVVDRTRLLRISTRIGLADSVRFLKRQTGVAVRAAAGYTPDHL
VTELRPLFEDPALRVLGWHLFTFNEIARTEQWRQALLAGEGEG
>V5EYW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio halioticoli NBRC 102217|TrEMBL
MGYTHASHIDALNQNVAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKALKPKFVSVTY
GANSGERDRTHSIIKEIKSQTNLIAAPHLTCIDASREELITIADDYWKNGIESIVALRGD
IPPNGGTPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPMTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRP
>A0A2N6GLU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sedimenticola sp|TrEMBL
MESQKKYTPTFSFELFPPKTEAGMEKLQTNVMKLSVVNPLYFSVTYGAGGSTQERTFESV
NWLVAKGFGTAPHISCVGSSREKIIEILTYYKSQNIKRVVALRGDLPSGAGLGGVGELNY
ANELVALIRSEFGDYFHIEVAAYPEFHPQAGNANSDLQNFKRKVDAGASAAITQYFYNPD
AYFRFIESCEKLGIDIPIVPGIMPISNYTQLARFSDSCGTEIPRWMRKRFEAMGDDIDSI
KSFGLDVVTTLCDRLLEQGAPGLHFYTMNQSHSVLKIWNNLGL
>A0A060NLA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serpentinimonas maccroryi|TrEMBL
MAQALPISFEFFPPKTPEGAVKLRAVRQQLYARRPEFCSVTYGAGGSTQEGTFATVAEIL
AEGVPAAAHFSCIGATRASVREQLRQLQGMGVRRLVALRGDLPSGYGSGGEFQYASDLVA
FIRAEFGGAFQIEVAAYPEVHPQARSPQADLQALLAKVRAGADSAITQYFFNSDAYFRFV
DEAQALGIEIPIVPGIMPITNSGQLLRFSDACGAEVPRWIRLRLLGYGDDVASIQAFGRE
VVGDLCEQLQRAGVPGLHFYTMNQSAPTLALCARLRQ
>A0A433FXA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. HSID17254|TrEMBL
MSSTFDASRVPFSFELYPPRSESSQEALHETVRRLAAAGPEFLSVTYGAGGSTGGRSLDV
LRFIREHTDVEPLAHLTCVGNTYAGATALIREFLDAGILRFLALRGDPPAGQREPFLGDL
ESAAQLVQLIDRVQAERAPYQESPVPGLPGAALVAPRQKVDIAVAAFPKGHPRATHRTQD
VEALLAKQAAGATFAITQLFFHPDDYLAFVERARAGGVTIPILPGIMPITSPARLARVLE
LTGEDLPSELAIALDVEPTAEGRREIGISWAARLAADVVAGGAPGVHLYAFNQHETVLTV
LAEAGIVPALRH
>A0A535XB60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGWRSASATSTSAASRSPAKRARSAASRCFWPVRSAASANPWRRSARSLQKRHGQAGVDL
LVLETFSSPIELREAVLAARSVSADLPISAQVSVHEEGKTLAGATPAEIVALLDALRVDA
LGVNCGVGPQTALDAIQQMRPLTRTPLSAMPNAGHPTTQGGRQIYVSTPEYFADYARRFA
EAGVSIIGGCCGTTPEHIAAMRSALPRNGAASVTIVESTDRSQARVDEPPLSLEAPRAET
SSPLARKVRAGELIISVEVDPPRGINPNKMLQGATLLKNAGVDCVDIGDSPMARVRMSCI
AFAALCEQRVGVETLIHFTTRDRNLMALQSELLGAHALGIRNVIALTGDPPQMGSYRDRR
VGRQVARLHPHHQAAEPGR
>A0A7G3A6T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp|TrEMBL
MSTSTPHVSFEFFPPKSDAMANRLWDTVQRLEPMAPDFVSVTYGAGGSTRERTHETVKRI
AQETSLKPAGHLTCVSATKEEVLAVAEEYWQAGVKHIVALRGDPPAGMGAAFDVYPGGFR
DAVDLVKGLREHRPELGKCFEISVSCYPELHPESRGWDAEIAYLKAKQDAGADRAITQFF
FEPETYLRFLDKARAGGVTMPIVPGIMLQANFRGLQRISGLCGATIPDWLADLYDGLDDD
VETRELVTANVAADLCRKLAEEGVENFHFYTLNRAGLALSTCRLLGLKPHPAKAA
>A0A7C6DQF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSTSDPASKSTTSTAVSSRSLRSVLGDPSTFARVVELVTNRGPLPPKRAARTVALARELA
CGGLAHAFSITDNPGGVAKVAPEALGLLLLEENQQVIIHLSCKDLNRSGLESRAWTLASL
GFENILAISGDLPAESYKGHAGRVFDVDSVGLIGLLRAMDEDIAKLRASQGRKEKGGLYV
GAAVTPFKYREDELVPQYFKLKRKLDSGAEFLITQTGFDSRKFDELLRYMEMRGMRVPVL
ANIFVLTPNVARYFHRNMVPGVTLSDELMAECEKQASSPDAGKAFFHEFAAKQIAIAKGL
GYKGAYLSGHLTCEEYGAIFSKAESYGENDWREFAREIQYAPKQRFYLLARDWTTGLNLP
ELSVEYQESITPQGRRKLRARVPAVYRVNRLVHNLVFKEGNPGYRLAASVYAAVALPPWH
PDPRVRLDRDG
>A0A7C4PDG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSEVISHNGYLSGSNLERVLRAGHFAVTGELGPPQSADGEVIRKKAALLRGYVDAVNITD
NQTAIVRMSSIGSAVIVLQEGLEPVVQMTCRDRNRLAIQSDLLGAYALGVRNLLCLTGDH
QTFGNHPTAKNVFDIDSIQLVRMVTAMRDERVFQSGEPFKGPEPRFFVGAAESPFADPVE
FRPYRLAKKIKAGASFIQTQLVYDVPAFARFMEKVRELGLHRQVYILAGVGPLKSPAMAR
YMNESVPGLRVPSELIERMEAAGAPWAGKSKDELTKEDKKARAAAWQQTGIQICIELIQQ
LRQVEGVAGVHIMAIEWEEAVRPIVEGAGLYPRPVVPAPTAEAAA
>A0A7C4PSN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MDLIADIYQRGLNTGRPVISFELFPPRTEEGWRQLVDRALPELLELKPDYISVTYGAGGS
TQERSLQLVRVLACDFQVTTLAHLTCVNATATQIRQVLTRFQEMGVSNILALRGDPPNNQ
ETFSPVDGGFTYAYQLVQLLRQMGGFSVGVAAFPEGHIACREGKLADWEHLAFKVGCGAD
FAITQLFFDNRHFFALQDFFRHRKIPVPLVPGIIPILSAAQIQKFTAMCGAEIPAVLAQR
LSAVAQDDAATVALGIEYATEQCRELLAHGAPGIHFYCLNKAASVREVLRRLKLR
>A0A7C4WNZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTKPTFLERLARGPLLADGAMGTMLYARGFSFDRCYEALNVEAPEVVLEIHRAYLQAGAE
LLETNTFGANRYRLVEHGLEDQVTLLNRAGVALARQAAMEVDRPVWIAGSVGPLGVPLAP
LGRVKAVEAREAFREQIAALAEAGVDVLILETFSSLPEILEAVRAAQETAPHLPIIAEMT
FAQDGHTLMGHTPEEVVETLLELGVPIVGANCSVGPAKLLPVIRRMASRVAQAGGPPPYL
VVMPNAGWPEMAAGRLRYPATPDYFAEYTHRFLALGVRILGGCCGTTPEHIAAMRRALEA
YAEPPAEDRRPIFRAVSPPAPTEPEPTDLARRLRAGLFVVSVEVDPPRGHDASALLEVAR
SLKAGGVDALNIADSPMARLRMSPWALAFLVQNHVGMETILHFPTRGRNLLRIQSDLLAI
HALGVRNLLVVMGDPPAQGDYPQATDAMDIVPSGLVQLIKERFNAGLDHAGESIGRPTAF
FVGVALNFNAPDPAREIKTLRRKIRAGADFIMTQPVYEPAALKDFLQRYEEQEGPLPIPV
LAGVLPLMSLRHAEFLHNEVPGIQVPEAIRERLRRAGEERARVEGLRIAQEVVAELAEFT
HGLYVMPPMGRYELVFQVMEAIPSRRRQKALPRD
>A0A6J2TYM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila lebanonensis|TrEMBL
MLGVGACRILRVVSYQNPILMKQRHVGSAQLVERTQGVKRREWSTADSNVYALETNSSRN
SLKPYQVPDDPNYEPCVTFTPNQTERCQKPIGALLADLTAQSKFFYGIEIIPRLGGKPLP
IDFNDFLPVLPTFVSVVWLATQYWNIDPIEAVDTVQLVKHLEPRIPTLPHLTVYRMSEQR
LDDFLALNLKNLLAVRGDKVHESQPYKDSEQLVRRAQCVRGESLSIGVAGYPEGYTNEPH
GAENPLASVQFLKQKVEAGAEFVIMQFCYRPEKIVQFILDCCAANINVPIIMGIVVPESF
KTYLLMEKFVGVRLPNELRARAEELQHCPAELAKFFEELALNNIQYVLDANVGVCGVQFY
TLNHLRSTIHILKKLHEMEILK
>A0A521TUD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAHRFLERLARGPILADGAMGTMLYSRGVSFDRSFDELNASRPDLVEQIHREYIVAGAEI
IETNTFGANRVRLAQHGLEGRVRELNNRGVRLAREAREITGESVFVAGSVGPIGQSLQPL
GSLSLYDARQAFSEQIEALLERGVDLFVLETFTDLSEIVEAILAVRAATDLPIVAQMSFG
DDRRLDSGMSASIVARSLALAGADVVGLNCGVGPQAALDVVREMRSASSVPIAAQPNAGS
PALVGGRTVYVATPDYFGDLARSFVAEGASLIGGCCGTTPEFIRAMRLGLAADPSEADRP
RVVAVAAPEPLAIEESERDDPHTLAAKLKRGDFIVSVEIDPPRGLNPRKAIEGAITLRDA
GVDCINIGDSPMATVRMSASGMALLVRRDAGVEPIIHCTPRDRNLMALQSDLLGAHANGI
RNVIAVTGDPPRIDSSPRSTTVWDVDSIGLIALLKRFNQGIDAAGKSIGRRAAFTVGCAV
TPTADDIDREVDRLRQKIEAGADFVLSQPLWSIEQLLAFEERVGRLPVPHILGILPLESS
KHAELLHNEVPGMTVPPEVRERMRRAGERGREVGLEITEELIQQARGRVQGVYIITSYGR
YDAAVDLVTSLKAAVGSTD
>A0A7C3JYP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAHRAGRTAMTKVTEAILAAGEDRAVFVCDFTPPRGSDPELLEGARHLARADFICVAYNP
GKLVRVDSVAAAFAVRERTGREVVFNLAPRDMNRLALESRLLGAGLLGLENVLVVQGDAF
TDRDGVPAAKDYTATGLIRAVKQLNQGLDYRGARLRADCDFCVGASLDLSRGIQDEARLA
AKKVEAGADFLVSQPVFDLTLISDFLSAFEKAAGAPLAVPVLWGLQILTAEGVLFSNVPQ
DLLRDLERGRDGVDIALETYALFREAGIAGVYLVSPILRGGARDYQAAARFMEQAA
>A0A7L3B0F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syrrhaptes paradoxus|TrEMBL
MVNENQHTCSASSSSKSDGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDKW
FSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKDEITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAQSYEADLRHLKEKVLAGADFIITQLFFRSETFLKF
MKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGVHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTGEESVFEVFTCYITREPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWGKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A3N5RMH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MFPLSPKRFQRAYLPVEPDRNWLVRVLTALERSVKGALFSCRMCGNCILQETAFVCPMTC
AKGLRNGFCGEASEERCVVDSSRPCTWLLIFKRAERLGRLERLLEINAPVDGAQAGHSTW
IPLFQYWAARKQPHLPDLITNPQMFGREWEQICREIRQPAWWQADSEYHPAGCNQPVSTL
EAELGTNPFVITGEIAPPDDCSTTMLLSKVNLLKQYVLSSNFSDNAFATSRMSSLACSKL
SLEAGLEPVLQIQCRDRSRNGILSDVMGASALGIRNILCLGGDYHNKGPSPRPYQPEQFD
IDSIQMLWMLRRLRDEGKHIDGRELEVRPKYFLGAAGSPFTLKPAYNAIRTEKKINAGAQ
FIQTQMVFDTERFGDWLEALEKRSLLGKVHILAGVCPPSSTDDVHSLAGEPGISIPKEYL
ERMDRAAEKDKGTGHKTHQQVKGVSIAVEIIQKLRKFNGISGIHMMVGGNEAILPDVIQR
AALEHVL
>A0A535QWV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQHDFLEQLQQHPLLCDGAMGTLLYARGIAYERCFDELNLTRPALIQGIHSEYISAGAQI
IETNTFGANRAKLEAYNLEGRVRDINRHAVKLAREAREISGQSVFIAGAVGPSGRPLQAP
DEQRLSELRAIFREQIDALLVGGADLLILETFSSLAELRQAVLAAQDVGGLPIVAQMSFY
EDGHTLSGQSPARVAAVLNDLGIDVMGANCSVGPAATLDVLQEMIAAARLFLDNEQAIPQ
MFSAQPNAGLPTRIGNRFFYMATPDYFADYAVRFARAGVQLIGGCCGTTPHHIAAMRKAL
NDAYGAATPSIPGSSRETLQAKPVEITNGKVTIAGLIEEEVILPQQGTKTRLQEKLAARE
FVVSVELDPPKGLNPAKILEGAAMLQKVGVDCINIADSPMARVRMGCIALARLIQDHLGI
ETIIHFTTRDRNLMALQSELLGAHALGIRNILSLTGDPLHVGDYPNTTGVWDLDSVGLIQ
VLRRMNEGHDAASSSIGAQASFHIGMALNLNMTEQETEQEIDKYRRKIEAGAHFIMTQPI
YELARLECFLARVGKPPIPMLLGCIPLHSSRHAEFLHNEVPGITIPDDVRSRMRAAGDQG
HEEGLKLAQELLTSARSMIQGVYLMPSYGRYDVVSKLTKMLQMQPTP
>A4JAE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia vietnamiensis (strain G4 / LMG 22486)|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPAADLQNFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATRTICERLTM
>A0A535YRZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAEFSDDHKARSNPFLQRLRRGALLGDGAMGTQLHARGVGFERSFDELNLTQPQLIEEIH
RAYISAGAELIETNTFGANRIKLARHGLEAQVRDINFKAVKLAREAREISGEPIFVAGAV
GPIGQQLEPIGRITIAKATAAFEEQIAALLEGGADLLVLETFTNLPELLAAVLAARRTSD
LPIVAQMTFAEDGLTLSAEEPTQVVQALEQAGVDVIGVNCGVGPQVALQVLESMRPHTAL
PLSGQPNAGLPARVEGRFFYFATPEYFANFARQAAELGVAYIGGCCGTTPAHIAAMRAAL
RPDTAAPQTRQPPSHTAVPIDLNPSEPLPRTPFAQRLADRSFVVSVEIDPPRGLNPAKCI
AGAQLVKAAGADAVNIGDSPMARVRMSALSLAVMIHRDVGIDTLIHFTSRDKNLMALQAE
LIGAHALGIRNVIALTGDPPRIGDYPSATGVWDVDSIGLIKILRRLNEGYDWLGTSIGRP
ATFTIACAVNPSAEDLQREIDRFRQKIDAGADVAMSQPLYDRPTLERFLERTGPLPIPFL
LGVLPLQSSRHAEFMHNEVPGITVPQPLRDRMRQAGENGIAEGLQQSRELLEDTKNLVQG
VYLMPSFGRYEVVAELVRWLRGQRVAPAARP
>A0A7C3JEF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTASVASRPSSRFLARLDEAPKPLLSDGAMGTMLNARGAGLKDCFDALNLSSPGLVVDIH
RAYLAAGADIIQTNTFGANRFKLAQHGLEDKVIAINQAGVALARNAIEAEARFAFIAGDV
GPLGVRLAPFGRVQLDAARQAFAVQISALAEAGADLIILETFSDLYEIREAIAAARQVCS
LPVVASMTFTRDDRTLLGDTPAKVAQELLASGADLIGVNCSGGPAQILRILKQMRRAAPG
GRFSVMPNAGWPEQVGGRIMYPAHPEYFGDYAIAFCEAGAALVGGCCGTTPQHIAAMRVA
LDREPFGCSPLLGEMAAVIEVDERQYQAETSSHLARTLASGKFTVAVEMDPPRGLSTHKL
LAGASLLADAGADVINVADSPMARMRMSPWAVCELIQRTVGIETTLHFPTRGRNLLRVQG
DLLAAHALGIRNVFIVMGDPTAIGDYPDAMDNYDLVPSGLIKLIKKNFNVGLDHAGGDIG
QPTSFFVGCALNLTPQDVAAEIKNLRRKIASGADFILTQPVFQPSAAQAFLRQYEEAHGP
LGIPLLAGILPLYSVRHATFLHNEVPGISISEGMMSRIEQAGSDAPQEGVRIALELIEQM
KGWINGIYLMPQFNRYDLAAEIIEGCSA
>A0A2M7PCL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG_4_10_14_3_um_filter_51_14|TrEMBL
MKDESRLKQLLDGGHFAVTAECGPPKGADPGAVLRKAGLLKEKVDAVNVTDNQTAIVRMS
SIAACTVLLSAGLEPVLQMVVRDRNRIALQSDVLGASALGIRNILCLSGDHQSFGNQPSA
LGVFDLDSMQFIEAVRGMRDAGTIMGGEQLTSAPAVFIGAAANPFADPLEFRVVRLAKKI
SAGAEFIQTQCIYNMERFKKWISLAEDRGLLEKAYILGGVTPLKSAGMAKYMKNKVAGMD
IPDDVIKRMDAVPKERQRQEGIGICVETILALKEIKGVKGIHIMAIEWEDAVGEIVERAG
LLPRPKVD
>A0A2W1B798|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKLSDLYGSGSPSISFELFPPRTIEALEALEDRLPMLIELGPSFISVTYGALGSNRSLTL
EISSLIKNKYGIETAHHLTCVGSSEREITTMLEEIRKHNIENIVALRGDPPRGDLVFNAP
ADGFSNGDELVKHIRDFWGFGIAVAGYPEKHIEAPDMETDLWNLKRKVDSGADAIITQLY
FDNSHFYKFVENCRAIGIEQPIVPGLMPILSVTQIRRITEMCGATIPADLMRKLEDAGDD
NSLVHEIGIEHTARQAKDLLDNNVPGIHFYVLNRHFHIAEIMQRIC
>A0A2E5F6Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLFKSYKPNKTIISFELFPPRTDXGIKTLKARLPHLXNLNPXFITVTYGAMGSTQTNTLE
IASXIKKTXDIDVAHHLTCVGATXDXINDTMNMLLANDIAQHCRPEG
>A0A535DNE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTRQGLIAFLQAPRYEVLPTEDVEDLVVAHVPKDITVTITASPRRGIEATVALAERLAAR
GYRVVPHLSARLIRDHAHLSEILARVNALGRSEVFVVAGDAKEPAGDFGDSVSLLAAIND
EPNGLRQIGVTGYPERHSFIEDDLTIQAMWDKRRFATYIVSNLCFDPRIVKKWVGRVRRR
GVELPIHIGLAGVTDPAKLMRVSTRIGIADSARFLRGHSNWFMRMVQPGGYDPERFATGL
LPDLAAPERNVAGLHFFTFNEIEATERWRQETLARLLAA
>A0A536FT75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLARSKPSISFEFMAPRDESEVDVMERTVAALAGHAPDWVSVTYRVRTGEKTLELVTRIK
RHYHIEAMAHLTCANTADRTRQILNWMEREGVANVLALRGDPPVSGEPFEPADPKLVHAS
DLITLVRGSGYRFGIGAACSTEKHPESPDLEHEFRYMQLKVDSGADFLITQLFFDNRFYF
DLVARARAAGIKVPIVPGLMPVPSRRSLAVMTAMSGATVPPDLQSAIDAAPDDDAIRALG
VRHCIAQCAELLEAGVPGLHFYTFNRARAPIEILAALRGQQLLAS
>A0A649PTD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni subsp. jejuni|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAAGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGITYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A3D5ANE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonosporaceae bacterium|TrEMBL
MPGPRPRISDLLRAGEPTFSFEFFPPKTPEGERQLWQAIRELEPLRPDFVSITYGAGGST
RDTTVSVTERIATETTLLPMAHLTAVNHSVAELRHVIGRYSDAGIRNMLLVRGDPPGDPQ
AEWIRHPQGVSHADELVSLVKASGDYCVAVAAFPEKHPRSPDFDSEVHYFVRKCRAGADF
AITQFFFNWEDWARLRDATAAQGCEVPIIPGVMPVTNVSQIERMAQLS
>A0A5K1J3K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella aerofaciens|TrEMBL
MRVDEVFKQTASQGTTPVSFEMFPPKGELTLDTARKVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNVSIEHLKQKQDAGATFFV
TQLFFDNEYFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A364V9K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium heidelbergense|TrEMBL
MPDSPRPAPLPYRQVAVSDTLRFNTPGRVPFSVEFMPPRDDEAELRLFTAAEAFHDLGVS
FVSVTYGAGGSTRERTLRVARRLATKPLTTLVHTTLVEHTVPELIHMVRAYASLGLTNLL
ALRGDPPGDPTGQWVQTPGGLRYASELIELVTAMPEGRFFDIGIASFPEGHYRANDLQQD
TEITLRKLRAGAQYSITQMFFDVDHYLRLRDRLAAADPTEGAKPIIPGLMPITSLRSVRK
QMELAGAQLPADIERELLSAAGGDERANRDRIREVGIGITTRMAERLIAEGAPDLHFMTM
NNVRATQEVLHNLGMAPAWGEEYGHDMVR
>A0A4R6TBC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus boseongensis|TrEMBL
MKITEHLANAKSTLFSFEILPPLKGQSLKELLEGIEPLMEFNPPFVDVTYHREEFIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRYHVDAVPHLLCGGFSKEETENALIDLNFIGVDNV
LALRGDAPKTEGRFIPEPEGHSYASELVEQIVRMNKGRYLHEETENSFHTDFCVGVAGYP
EKHFEAPSMKFDLKYLKEKVDKGAEYIVTQMFFDNQKYFEFVDKVREAGITVPIIPGIKP
ITTIGQITMLPRTFFLDLPDALTDELEKCKTNGEVKEVGIEWAIQQCKELVSANVPSLHF
YTMSKADATYKIAKEVF
>A0A523HN08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSPSSRLESVLRSGDFAVTAELNPRDSADPQAVYQQARMLAEFSDAINTGDGSGANPHLS
SLGMAALLARAGHEPVMQLGCRDRNRIALQGELLAAAVHGVANVLCLTGDGVQAGDQPDA
KPVFDLDSMGLLRTARIMRDQGRFLSGRKIKIPPRWFLGAASNPFVPPYDFRPLRLQKKI
EAGAEFIQTQYCFDVPRLRQFMAQVRDMGLDERVFILAGVGPLRSLKSALWIREHVPGVV
IPESIEARLRGVVSDKQQEEGLRICVEIIQQVREIPGIKGVHVMAYGQEQWVGEIVERAE
LLPRPKPAGGQFVAKSAKDVSL
>A0A5M7LII6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. VH_25|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRGELRNIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLRRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMSAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAAA
>A0A2E2AL07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSKIPDLADNGSSCLKIICDFSPPRGGMPSLIGDLDGLNPDIVSVAYNPGKSVRVNPVAA
AAWIKANTKQDVVFTLATRDMNKVAIQSLLLGAQLLGLQNIVIVEGDGLSNRDRERFKAV
YDFQPTSLIESVRDMNQGKDFRGLKLRVATDFSVGATIDMGRPSDSEIPLAVRKAQAGGK
FFLAQAEFDPSVIARFRADFESHFDKGHAPPVFYGVQILAKDGIIFGNVPQRTRSELESG
RSGEEIALELIQNLMVQGVRTVYLVPPIFRGGRRDYDSARRVIESARRLAS
>A0A179BQV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus ferrooxidans|TrEMBL
MAHSVEFFPPKNAAGEERLREAITALLPLGPEYASVTFGAGGSTRERTFATVTMIRQDYD
LEAVPHLSCIGSTEAGIREILEDYQKQGVRRIVALRGDLPEGMENPGHFQHAADLVAFIR
HFGGFDVYVAGYPEIHPRATSARDDVAHLVTKVRAGADAIITQYFFNPDAYLQLRDDLQR
QGVDVPVVVGVMPITNFEQISRFSAMCGADIPQYVRRRMEAYSDDPQSQYQLGIELLSRQ
CRLLLREGAPSLHFYTLNQAEATAAIWRNLSL
>A0A535L4T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLVGGRPTVSFEFMAPRDESEVDALEKTIAALAGHAPDWVSVTYRKATGDKTLEL
VTRIKRQYHIEAMAHLTCANTADETRR
>A0A2W1KJ38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus ferrooxidans|TrEMBL
MAHSVEFFPPKNAAGEERLREAITALLPLGPEYASVTFGAGGSTRERTFATVTMIGQDYG
LEAVPHLSCIGSTEAGIREILEDYRKQGIRRIVALRGDLPEGMENPGHFQHAADLVAFIR
HFGGFEVYVAGYPDIHPRATSARDDVMHLAAKVRAGADAIITQYFFNPDAYLQLRDELRR
EGIEVPLVVGVMPITNFEQISRFSAMCGADIPQYLRRRMDAYAADPQSQYQLGIELLSRQ
CQLLLREGAPSLHFYTLNQAEATAAIWRNLGF
>A0A3N5LMX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAAINFTDCPSAMPRMSSWACSTLAIQNGAKPVMPIAARDRTRTSLQADVLGAAALGVRN
ILCLSGDSMRMAPDPRGRMDVVDFDSVQMLWILRRMRDEGKYLDGRTIKFPPKFFLGAAA
SPYASRPEYQAIREHKKINAGAQFFQTNLVFDPERMEVWLNELAKRNILDKVFILVGITP
LKTLKMAQYMHEEVPGVTIPEKLLKRMEAAGDGAEEVGIAIALELIEAVKKLARTGSGGG
ISGIHLMAVGWEEIVPRIVTEGGLVREASGAIE
>A0A402BMF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusaceae bacterium|TrEMBL
MRIAIELVPRDEASLLAELDVIKEHYQAVDTINIPDLLRYDMRSWEGCIHAQSNYEFVIP
HIRAIDINLDKPLPMADFLREHHINEVLVITGDPPQDMRWKIYPTTSIDVIRKFKEELPG
IKVYAGIDQYRDSMRKEADYIKRKIQAGADGFFTQPFFDLRLMEIYSEILAGQEVYWGVS
PVTSEKSLNYWETKNNVVFPADFQPNLAWNLAFAQQALAFTKQTQTNIYFMPIRTDINKY
LQGIFSNPV
>A0A536RVA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVRPLGAQSVGQALAAFLRTPRYEIFPTDDVLERVATNVPPEVTITVTASPRRGMPTTIR
LAVSLAQLGYRVVPHLSARLIRDHVEVGQIIEALQAAGIRNVFVVAGDAREPAGLFPDSV
SLLSALPPDHGLTEIGVTGYPESHPFIHDDVTIQAMWDKRRLATYIVSNMSFDPDGVKRW
VDRVRRRGVDLPIHIGMAGVADPAKLLRLSTKIGVADAARFLRGHPSWVARMFRPGGYDP
GRFTGALMPDLAQPERRIAGLHVFTFNEIEPTERWRREMLARLS
>A0A1H6Z7A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frateuria terrea|TrEMBL
MPAISFEFFPPKTDEQRAQLDRAAQVLKAYAPDYVSVTFGAGGSTLSYTGDTVARLHGEH
GLSVAPHLSCMGGTRAEIAALLEGYRAAGYRRIVALRGDLPSGMASPGDFRYAAELVAFI
REHSGEHFRIEVAAYPETHPQAEDALRDLAHFKAKVDAGADGAITQYFFNPDAYFRFIDD
VRRLGVAVPIVPGIMPITNFSQLKRFSDACGAEIPRWIAKRMQAHGDDAESIRALGAEVV
AQLCRRLLEGGAPGLHFYTLNRARATQAVLAQLH
>A0A535JNB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIAELLGRSRPTISFEFMAPRDETEVEVLEKTIAALAGHAPDWVSVTYRLRTGDKTLEL
VTRIKRQYHIEAMAHLTCANSVDQTRHILNWMEREGVANVLALRGDPQESDDHFVPADPE
LAHGSDLVAFVRRNGYGFGIGAACSAEKHPESPDLDHEFRYMKLKVDAGADFLVTQLFFD
NRFYFDLVARARAAGIKVPIVPGLMPVQSRRSLAHMTAMSGATVPSALRRTIDEQPDDDA
VRRFGVEHCIAQCAELLEAGVPGLHFYTFNRAKAPIEILAALRGQQLIAS
>S2KVJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas anticariensis (strain DSM 16096 / CECT 5854 / LMG 22089 / FP35)|TrEMBL
MPQAERAAGGALEAKSGGFAADSLERRIQGLCHGWSLEVTPKTAIHLAKAEPPPAAGSQV
YITHLPGQPFEDVIATAAWLRARGYDPVPHLVARSVPDRATLIDWLDHLTQEAGVDAVLL
IAGSMATHLGPYPDTLTLLEDVCLAEHGIRRLAVAGHPEGHPHADDEALDQALATKLAHA
ERDGLEIWLVTQFLFDAQPLLGWRQRLVAQGLEIPIRVGLPGPASLATLWKYAMSCGIGA
SVAALQKQGSRMLQLARPKPPSRQVLGLARHATSNLALHFYPFGGIDKTLAWSQALEAGR
FRLDARQHEIIVDD
>A0A6B3CXB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID6648|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PESLKERILAAKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A536JEA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGALASLLRSGEFVVTAELNPPKSAADGLVRRRAEALRGVVDAVNVTDSNRAMVAMAAIP
AATIIRSAGLEPIVQMTGRDRNRIALQGDVLGAAAIGIENFVFMSGDDPKQGNHPDAVYV
KDLDGVGLVRMAVGMRDQARFLSGDEIKQPPKMFVGATASPFTKPVEADLTKTLEKIAAG
ADFLQTQPVFDLATFSRWLIEVRRGASRDVPILAGVLILRSAEQAERLSKVPGVALGAEV
IDRIKKATNPEAEGIAIAVEMVKELKALPGVRGVHLYAIEWPEAVGRVVEAAGLLPRPEA
RIPA
>A0A535UHD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTRGYCGRLPAVRIADLLNRGRPTVSFEFMAPRDEDEVGILERTVAALAGHAPDWVSVTY
RVRTGEKTLELVTRIKRHYHIESMAHLTCANTRDETRRILNWMEREGVANVLALRGDPPG
PGEPFQPVDPELAHGSDLVAFVRRNGYRLGIGAACSTEKHPESPDLEHEFRYLQLKVEAG
ADFLITP
>A0A2E5BYA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLSITELIRSSSQTVYVLDVSPPRSGNDLLXQELLDLTPDVFSVAYNPGLSVRVNSVMLA
SWXQNSTGIPTSFFLATRDMNKLALQSLLLGAQLHGLNNVTVVQGDAFSETKLQFVKGVN
DFTXTEFIXAIKNMNFRKDFENKNLIYPTDFCLGATVDLSKDLEXEAELLHKKIXXGSDY
IVFQPFFDFDLPEKLFXIFYKKFHXHVDXPIIWGIQMLENFSKSXSEIPNWVLDELSKGR
PSIEIAQEMIEDLKNTQKVGSVYLVPPIFENGXRNYEVANELLTLIR
>A0A7Y3J0X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MLKPYPERLRDGVLVFDGAMATYLFSKGVYLKKCFEEVCLTNPQMVLDVHREYISRGAQA
IETNTYGANPIKLKGFGLADKTEQINRAAVRLAREAAGDTVYVAGSAGPTGRLLAPEGPL
SEEEARSSFEAHLGALVRSGVDLLLLETFSSRRELALAVEVARRLAPEVPLQAQFTFSRT
FLPGPEAYKAEAQAWAAFFETLDVDAVGMNLMGPTEALEVLAVLKKTVTKPIAVMPDSGF
PKEIDGRQFYLTSPEYFAEFAKLYVDGGALVVGGDCGTTPEHTEKMAQAVLSFDAGRRAV
RWTPVTSAVEKPVVPLAERSKLGQALATGRWVNLVELVSPLGVELSGLLEKARALQAGGV
EFVNFPDGPRASARLSALVAAIEVARATGMESVLHMACRDKNLIGLQGDLFGYHAAGLRN
VLLVTGDPPKVGKYPNVTGVFDTDAVGLTRIVRRFNAGVDMGGDELPAVTSFVHGTGVNP
AFPVPEKELERAKLKAEAGTEYFITQPVWDVDQLERFLDELQKLGKPVILGVWPLASYRN
AVFLASEVPGVVIPPAILTRMERHTDKDAARSDGIAISREIIQRLRHRVQGIQVSPPFGN
VRTALEVVKGW
>A0A832KPK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MKVIDILNRAKKPLFTFELVPPLKGGNAEVLLDTVRSLSLFEPAYINVTNHQAEVVYNER
PDGLLERRIVRKRPGTIALSSLIQHTFNIPVVAHLICGGMQSEEIEDALLELNFLGIKNV
LALRGDPPQGQKRFVPIKGGHQYSSDMVKQIDNLNQGIYLDEALVNGEKTDFCIGVAGYP
EKHAEAANRITDMEHLKHKVACGAEYIVTQMFFDNSVYYRFVEECRQNGITVPIIPGIKP
IGSKRDLATIPQTFHVDFPPELVDLLHRAKKLSEVKEVGVYWSKKQAKDLIEHKVPGVHF
YTLGKAEAVSQVVRDVY
>Q8DX11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)|TrEMBL
MSKFLEKLKTDILVADGAMGTLLYTYGLDTCHESYNVTHPEKVLAIHQAYIEAGADVIQT
NTYGAQRHRLKNYGLEDQVVSINQAAVNIAHQATLGKETFILGTVGGFRSQRQCDLTLDN
IVEETLEQVEALLATGQLDGLLFETYYDIEEITTVLKIVREMTDLPIITNISLHEAGVTS
NGKPIVEALSQLVMLGADVIGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASQLSLDGE
NSQYQFSQNSEYFGKSAELLVAEGVRLIGGCCGTTPDHIRAVKRSIRGLKPIERKVVTPI
IPVKDFVRRIRRTDTLVDKVKKEVTIIAELDPPKHLDIVQFQKAIRAIDQKGIAAITLAD
NSLSNTRICNLSIASLLKDEISTPFLLHIACRDHNLIGLQSRLLGMELLGFNHILAITGD
PTKLGDFPGATSVYDVTSFKLLSLIKQLNQGLSYSGASLRRPTDFTVAAAFNPNVKNLTR
TVKLIEKKVASGADYFMTQPIFDHSVLKELADLTKTVEQPFFIGIMPITSYNNAVFLHNE
VPGIKLSESFLSALEKVKDDKEACLTLALNESKSLIDEALNYFNGIYLITPFLRYDLTLE
LIDYIQKKQVRKSS
>K9T3R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pleurocapsa sp. PCC 7327|TrEMBL
MVNRFRQAVLEREFLITAEITPPKGGNPARMIEVAKMLKGWVHAVNITDGSRAVLRMSSI
AASAILLQHGIEPICQMTCRDRNAIGLQADLMGAHALGIRNLLALTGDPVKAGDCQAAKA
VFDLESVRLLKVIDKLNQGFDSNQRSLPDEPLDLFAGAGVDPQLKSWSGLQRRFEKKIEA
GAQFFQSQLITDFERLDKFMHQIAAGADKPILAGIFLLKSAKNAEFINRYVPGVKIPQDI
IKRLADAPDPLQEGVNIAAEQVRLAKQLCQGVHLMAVKREDLIPQILDLAGMSPVACSEA
ISGLLV
>J2X329|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM25|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVTEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A1S2PXP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MUSC 14|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMAQWVPHPKGLTYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAATCDTPVIPEVLPVTSVKMLERLPKLSNAVF
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A5B2ZBJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenimonas fontis|TrEMBL
MPRISLEFYPPKDEEQRAQLDRTVARLKSHAPAFVSVTFGAGGSTLSYTPETVRRLRQEH
GLDAVPHLSCMGGTRTELRELLKLYRALGCRRIVALRGDLPSGMARTGEFRHARDLVAFI
REEHGDHFRIEVACYPEMHPQAEDALADLRHFRAKVEAGADGAITQYFFNADAYFRFVDE
ARRAGVTVPIVPGIMPIANFAQLRRFSEACGAEIPRWIAKRMQAYGDDAKAVREFGADVV
AAMCRRLLEGGAPELHFYTLNLARPTEAVLSRLA
>A0A200R392|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macleaya cordata|TrEMBL
MKVIEKIQQAAAEDRVVFSFEFFPPKTDDGVENLFERMDRMVSHNPSFCDITWGAGGSTA
DLTLDIANRMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVPIEGGFACALDLVNHMRAKYGDYFGITVAGYPEAHPDMIGSDGLASPEAYQSDLAYLK
RKVDAGADVIVTQLFYDTDNFLKFVGDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMDKSALAILLNL
GLIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSRNP
SYGALTDYQFMRPRSRDKKLNEEWAVPLKSVEDIHEKFSKLCLGKLKTSPWSELDGLQPE
TKIINEQLGSINLKGFLTINSQPAVNGEKSDSPTVGWGGSGGYVYQKAYLEFFCSKDRLN
SLIEKSKAFPSLTYIAVNKEGTSLSNVGPTAVNAVTWGVFPAKEIIQPTVVDPASFVVWK
DEAFEIWTKGWARMYPEGDSSRSLLESVQSSYFLVSLVDNDYINGDLFGVFKDL
>A0A415N4N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides intestinalis|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNRYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELACEAMKCKTDEEAKQVGIEWCVKQCKELMEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A1A7KIJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. MOF25P|TrEMBL
MKITDHIKNANGKALFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTLGGHASAMDLVGQINNLGRGKYLHNDEQICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVTKAREMGITVPIIPGI
KPIATKNHLKLLPQVFKIDLPEDLINAVEGAKNNEAVKQIGIEWAISQCRELLDFQVPVL
HFYSMGKSDNIKKVAGELF
>B7NFP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A509MT41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter halodurans|TrEMBL
MQLVHEQMTDPSVDNACDEELDSLARSASMELTPRQILGTDDLNRWLAPGTAVYVPFLPK
ADYDDTVKACSQLRATGLDPVPHFPARAIASQEQGREWLERLGAAGVDKLMLIAGDNDRP
AGPFKDTLALLESGLLTRYPFALGVAGHPEGHPSADHPSLMQALQIKRDYAAETRTRMWV
TTQFAFEAGSFTDWLHTAGDHLAPLPVYFGIAGPTKLRTLMAYAAQCGVGVSARALMRHP
ETTRLLRSWTPDGLVEALAQYRVAHPLTLFRGIHLFPFGGLKRTSQWLEDLSNESPDCAA
SRSSI
>A0A089HPS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus durus|TrEMBL
MENRLKDKIRNKETGILTYGMTPPKATHPPEKIAEISQKQCERIKDLDIDALILYDVQEE
ADRIEQERPFPYLSTIDPTTYSNVYLNPLSVPKIIYRCVGKYSEPQLVDWLKSDMDQDRF
SVFVGSSSSQQEVKLDLTEAYRLSKQHNRGLTFGGVVIPERHMKKNDEHIRVANKVKSGC
SFFVSQATYDVEASKNFLSDYFYYCTNNGLEMVPILFNIAPCGSPKTLEFMKWLGISIPK
WLENDLKYSSDVLDKSITLTQKIFAELLEFGLEKGIPVGCSVESVSTRKVEIEASVQLVK
DIKSILDNKLSRAAVI
>A0A380T7W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas wadenswilerensis|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRSLLTQYQAAGIQRIVALRGDLPSGMGMASGELRYANEL
VEFIRQESGDHFHIEIAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFY
FVERVQQMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAYG
EEIITRMCEQLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>R7PLT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium clostridioforme CAG:511|TrEMBL
MKTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTREDVLLILEQLKEQKIENILALRGDRVPDREPAGDF
RYASDLVEFIKLHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFRERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVKLPKKFISVMERYGDNPIAM
RDAGIAYAVDQIVDLVAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>A0A842HXA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasphingopyxis marina|TrEMBL
MNLTVKQLSEARRALDEPLFADLAGDVDVSFEFFPPKTDRMGETLWSSIRTLEPLSPRFV
SVTYGAGGTTRERTHATVRRIVEETGLDAAAHLTCVGASRAELETILRDYWDAGVRHIVA
LRGDPQGQGERYASHPDGYSSAADLVAGIAAVRPFEISVAAYPETHPEAHSAKTDLDNLR
RKLDAGATRAITQFFFSADTFFRFRDAAAAAGIDAEIVPGILPVSNVAQTRKFAHMCGAQ
IPPWMDRLFEGLDDNPAARQLVAATVTAELCRKLYAGGAREFHFYTLNRAELSYAICHLL
GIRPRLGEQKRAA
>A0A1C5Q638|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MNLREYLKTTNLITDGAFGTYFAAKYQTQDIPELANITAPEKVKKIHEEYLNAGAKFIRT
NTFASNTETLQEDFAEVEKNIQAAVEIARDAVNGRDAWIAGDIGPIPVNGAEDAAAAADE
YYQIAKTFAERGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIGEMSSWDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLSVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTEEDAARLRRIKEETGAKILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIRLAKEVMKMVEDFADGYYFSFPFNRVYMLQEIMGK
>A0A7X5RLY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas profundi|TrEMBL
MVSYAQGVDALNQSLSELRDIDVSFEFFPPKSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIHQQTGVAAVPHLTCVDASREELTQIAKDYWDSGIRRIVALRGDLP
PGVEKTEMYASDLVALLKDVADFDVSVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTSVFLRFRDRAAAAGIDLDLVPGILPVTNYQTLVKFAGFTNVHVPGFLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRADAK
>N9NWZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 101966|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHNVAGIVITPHMLRALAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVKT
KNELVPELAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDLCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A7S1B9J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corethron hystrix|TrEMBL
MTAMADPKIIDLIRAEEEKDGWTSLEFFPPKSAEGVKNLTKRMERMKVTKPLFTDVTWGA
GGSTADLSTTIAKTMRDVGYVANLHMTCTNMGDDIDPITAIKNALDEAKDAGIRNIVALR
GDPPHGQDEWTAAEGGFTCALDLVKFMRKNYGDEFGISVAGYPEGHSKAITQLTEEEANN
MTAAEKGRCSMRDGVTYVCKDEDYEKELIYLKEKVDAGSDFIMTQMFFDTAVYGTFVKDC
RARGITCPIVPGLMCINAYRGFMNMTKFCRTRVPESLLAKMEEIKDDVDAVKAFGVSFGI
QMCKDILSYNDTKGLHFYTLNLEKVVYGILDGLGITNSASKKTDESDAKSMQAVGSAWAR
VGDNIKTSYGGLGTVTDIREDGTTVVLLDKWDLANGQRPTLYLRPNAYTKVMAA
>A0A829YJL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steroidobacter agaridevorans|TrEMBL
MSVEKLKDQIGNSLSKLRGRPTVSFEFFPPKDEAMEKTLWESVERLAPLQPRFVSVTYGA
DGSTRARTHNIVTKVQKNTALTAAPHLTCIGAPREAILDIARDYWANGIRHIVALRGDPP
QGTTKYVPHPQGFAYAVDLVKGLKSVANFEISVATYPEPHPESPSAAFELANLKSKIDAG
ADRAITQFFFDTEVFLRFRDQCAAAGIKASIVPGILPITRFPQMFRMAQRCGASVPDWLS
HRFDGLDDDADTRRLIAAAVAIEQVQELQKHGVEEFHFYTLNRAELSYAICHALGVRPVL
AQAAAG
>A0A7S1B9M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corethron hystrix|TrEMBL
MERMKVTKPLFTDVTWGAGGSTADLSTTIAKTMRDVGYVANLHMTCTNMGDDIDPITAIK
NALDEAKDAGIRNIVALRGDPPHGQDEWTAAEGGFTCALDLVKFMRKNYGDEFGISVAGY
PEGHSKAITQLTEEEANNMTAAEKGRCSMRDGVTYVCKDEDYEKELIYLKEKVDAGSDFI
MTQMFFDTAVYGTFVKDCRARGITCPIVPGLMCINAYRGFMNMTKFCRTRVPESLLAKME
EIKDDVDAVKAFGVSFGIQMCKDILSYNDTKGLHFYTLNLEKVVYGILDGLGITNSASKK
TDESDAKSMQAVGSAWARVGDNIKTSYGGLGTVTDIREDGTTVVLLDKWDLANGQRPTLY
LRPNAYTKVMAA
>A0A346A237|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudolabrys taiwanensis|TrEMBL
MNAPIRLSRHKRDPRHLNVSFEFFPPKDEAMEKILWDSIERLAPLTPDFVSVTYGAGGST
RERTHATVKRILSDTPLTPAAHLTCVAATREEIDGIVRNYHDAGVRHIVALRGDALEGAG
AAYKAHPGGYETSAALVAGIKRIAPDFDVSVSAYPEKHPDSPTIEADIDMLEAKVDAGAD
RAITQFFFENDLYFRYLDRVRARGINIPIVPGILPVQNFKSARNFAERAGATVPNWLAER
FNGLDDDPATRKLIAAAVAAEQVLDLVDRGVTHFHFYTMNRADLVYAICHLLGMRPAVEQ
AA
>A0A1C5KK98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKMKELFDRGEFAVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNPLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A1G8I121|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter gossypii|TrEMBL
MGVRGQMKIPEHIANANGKTLFSFELIPPLKGQSIQGIYNAIDPLMEFKPPFIDVTTLRE
DFIYKQHPSGLLEKLSYRKRPGTIAICAAIMNRYKVDTVPHLLCGGFTKDETENALIELE
FLGIENVLVLRGDARLGDSSFVPTPNGHCYATDLLQQVVNLNNGIYLHEDHGNTAKTNFC
IGVAGYPEKHFEAPNLKTDFKYLKQKVEMGAQFIVTQMFFDIGKYKEFVNGCRANGINVP
IIPGLKPITSSKQLVTLSKTFHIDIPEDLSDAIHACATEKDVKEVGIEWMINQCKELIAF
GAPVLHFYTMSNAGPTKRIAEAIF
>A0A1C6DBI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MSKLREAFEKGEFAITAEMAPPKGTDLSHLAECAKLVIGRVHAANVTDNQSAVMRTSSLA
TCKMLKDLGLEPVIQMTGRDRNRIAIESEMLSAGFFGIDNLLALTGDHVCVGDHKQAKPV
FDLDAVSILSTATMMNNGTDSTGLELKGKTDFFLGACVTPEYDPIEVQLLKMEKKIKAGA
KFFQTQAVYDIEHMRKFRELTKDMDCKVMAGIVPLKSPGMAKFMTANVPGIFVPDDQIER
LKAAGKGNYVAEGIKMAGEFIKQLKEENLCDGVHIMAIGAEENVPLILDAAGL
>A0A358N1Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula sp|TrEMBL
MSLASHFATSRCAISFELFPPKTEAGLKALCDNVTRLQQFDPAFFTCTYGAGGSTQGATL
DVLEKVRELTELPVASHLTCVNSTVAELEAYLNQAKERGTDYIVALRGDPPQGTTEFRAI
AGGLHYANELVELIRKQFDFGIAVAGYPEVHQEAPDAQTDLDNLKRKVDAGADIIITQLF
YQNTDYYRFRDNCESAGITIPVVPGILPVTNFKQATRIASMCKAAIPSELASAMTATDDP
ADQFQIGVEHARAQTLDLMAQQVPGIHYYVLNKSDAAAALLDGIQTPSS
>X0QS71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. JCM 18902|TrEMBL
MTKPAFSFEFFPAKTELGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRNRTLDIVQALCA
RGDTDIAPHISCIGDDKAEIAELLDLYKGLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREYSGDHFHIEVAAYPEMHPQARSFAFDVDNLVNKYQAGANASITQFFYNADSYLYLR
DTLEKRGIDTVAQPLIAGIMPITNSSNLVRFADSCGADIPRYVRKQLSDFGDDRKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLA
>A0A4R9GRK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira fluminis|TrEMBL
MKKILEIYNNAKGPVYSFEFFPPKTDEGEGKLTETLRELSRLQPGYITVTYGAGGSTRDK
TIRLTSDLAKQFDLPAAAHFTCVGGNREEIRSILGEIYSSGIRNLMALRGDPPKGQGEFQ
KAEGGFGHASELISFIKSEGFDFCIGGACYPEKHPQARSLEEDVDNLKKKVDAGASYLVS
QLFFKNEIFESFLGLVRKKGISVPVIPGIMPITSFSQIERFRAMAACEFPEELLSDLEEV
RNRPEEFYRRSLNFSVRQCRELLSLGSPGIHLYTLNQSHASYDIVRELEN
>A0A1G6URQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimonas voraii|TrEMBL
MPALPSLSFEFFPPKTDEQRLQLDRTAEKLRTYSPRFVSVTFGAGGSTLSYTADTVRRLH
EQHGLDAAPHLSCMGGTREEIRTLLVQYRAIGCRRIVALRGDLPSGMARPGDFRYASELV
EFIRKETGDHFHIEVAAYPEVHPQAEDALADLKHFCTKVRSGANSAITQYFYNADAYFAF
VDAVRREGIDIPIVPGIMPISNFSQLKRFSEMCGAEIPRWMSKRMQAYGDDAAALREFGA
DAVAALCRRLIEGGAPELHFYSLNLAKPTLAVLERLG
>A0A2D5XCS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon|TrEMBL
MKKITEILKEKDFTISVELVPPRNGTNLEESFSKIAQIKDMVDFISVTKGAGGSLRGGTL
PITYFTQKKFGINSIAHFVCRERTKQEIENNLIDLYYFNIKNILALRGDPPAGSNEPWDG
DYEYAYRLVKQINDLNNGEYIPKQEQDKKYRSGIKTDFCILVAGHPEDPVEKELAHIKSK
VDAGAEVIITQMVFSFDDYKNYVEALRKASINIPVIPGIRPITSLKQADSIENFFKIPIN
DEIKKRLKEEGKDFGLNYFADMIKKLQDYGAPGVHLFILNDIDLVNDLLERI
>A0A6J7VV20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARISDLIAAGRTYSFEFFPPQTQAAQMSLGRAIAELSPLAPSFVSVTYGAGGSTRERTR
EVVTWVRKETDITPMAHLTCQGHRRSEIKEILDNYADAGVENILALGGDVPLDGEVQPSD
YTFASDLLDDVLADGRFSVGVAAHPEHHPRSPDRATDRRYLAAKLGSSDFAITQFFFEVD
VYVRMVDELRALGVDKPVLPGIMPVTNKSQILRMAAMSGAAFPEWLAQRLEAFEDPEDIR
RVGVEAATELGQALLDAGAPGLHFYTLNRSTATREIYANLGLPIEQ
>C2PJX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLNTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6J5Z2R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MNEAKGRELTYSFEFFPPKDSEGEARLWSAIEGLESIAPDFISVTYGAGGSTRDRTIRIT
SEITARTNIPTVAHLTCVGSTREELIEILAKYRAAGISSILALRGDPVGGPRAPWQVTPG
GFNHADQLVALAREIGGFTIGVAAFPDGHPASADGLDDDIEVLLNKERAGASFATTQFFF
EAEKWSALVEKLAAKGSSMPIIPGILPVTNVKQLNRMSELSGTPIPTDIAEAFAAVEDNP
DDVRKLGVEIATKLCRDLIAAGAPGLHFYTMNTSSATREIFEAIK
>A0A8C5NYA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jaculus jaculus|TrEMBL
MVNEARGSGSSSGSESSKDSSRCSTPVLDPERHEKLREKMRRRMESGDKWFSLEFFPPRT
TEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTALNYCGLETILHMT
CCRQRPEEITGHLHRAKQLGLKNIMALRGDPIGDRWEADEGGFSYAVDLVKHIRSEFGDY
FDICVAGYPRGHPEAESFEDDLEHLKAKVSAGADFIITQLFFEADTFFSFVKACTEIGIT
CPILPGIFPIQGYSSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVNLCREL
LDSGLVPGLHFYTLNREVATTEVLKCLGMWTEDPRRSLPWAISAHPKRREEDVRPIFWSS
RPKSYIYRTQDWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEE
SVFQVFEHYLSGEPNEQGYKVTCLPWNDDPLAAETSLMKEELLRVNRQGILTINSQPNIN
GKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENIT
NAPELQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSRMII
QYIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLNRQTSNKRETEDL
>A0A6J7DAH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRIDDILRSGTDPVFSFEFFPPRTPAGEEQLYEAIAKLAPMHPAYVSVTYGAGGSTRGKT
LEIVSTIRERHGIEAMAHFTCVGATVDDLRETLDEMLRLGFENILALRGDPPAGQDEWVR
TEGGLEYSRELVELIRAGYPMAIGAAAFPETHIHATSPQDDLRHLKEKVDAGVDFLITQL
FFDNAVYFDFVSRARAIGIDVPIIPGILPVTNIAQLDRITALCGSEVPAGLRAELDLRAE
ELEAVEDFGVAYATLQCAELLAGGAPGIHFYTLNRSPATRAILGALRLQRPWDPARA
>A0A7Y2C388|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospiraceae bacterium|TrEMBL
MKVTDYFEKSESTLVSFEVLPPLKGGSMDAIFKTLDPLMEFKPPFVDVTYHREEFIYKKK
DSGYYEKTSIRKRPGTVGICAAIMHRYGVDAVPHLICGGFTKDDTENVLIDLAFLNINNV
LALRGDARKFDGKFVSQPGGHAFALDLVKQITDMNNGAYLDQNIQNGNKTEFCIGVAGYP
EKHFESPNMDMDLHFTKLKVDAGADYIVTQMFFDNQFYFDYVKRCREAGITVPIVPGLKP
LTKRYQLNSLPRLFYTQMPSDLVNAVNAAKDDQAVKQVGIDWCTAQSKELKEFGVPCLHY
YTMGDSKIIQKIVEGVY
>A0A3M0XDZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Woesearchaeota archaeon|TrEMBL
MKITDILKSSTKPIVSFEITPVDKGASIKSLEPTLESLASFNPPFIDVTSRAEELKKVKS
ADGLKAVPYRKRVGTGMICAKVQFQYGIPAVPHVLCNGFTCEETEDFLVELNYAGIENVL
ALRGDPLSHNKFVPDYRSVNHTALDLVEQIVDLNRGSYLRSEQGHPTDFCIGVGAYPEKH
YDAESLDEDIAWLKRKVDSGASYAVTQMFFDNKRFYHFVDKCRDFGIDIPIIPGLKIFTR
RSQLKTLPKVFNLSFPYKFKEEFIKVKKGGVLDFGVDWARRQIEDLFSHPEYFNERPIAH
IYVLGSSKPVEKLMSRLSI
>A0A6J5Z9Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRIDQLIAEGSEPQFSFEFFPPKTEQGEENLFEAIEQLAPLEPAFISVTYGAGGSTRDKT
IEIVSRIRDRHGIEAMPHFTCVGSTVDELRETLDKMAEIGVENVLALRGDPPGGESEWTK
TEGGLEYSRELVELIRAEYPFAIGAAAFPETHIHATSAEDDLDFLKQKVDAGADFLVTQL
FFDNDAYFDFVQRAREAGIDVPIIPGIMPISNVAQLERMTTLCGATIPPALHEALLARGD
DARAVEALGVSYATLQSAELLAGGAPGIHFYTLNRSPATHAILGALKLQRPWISR
>A0A6J5Z2X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRWTLAKSHLPCAKLPSRHPANLAGDAKINEQLRIKHDGHAGLVVCASTLGGSLQIPTLS
FEFFPPKDADGSVALSNTLETLAAYNPAFASITYGAGGSAQERTFAAATIVKDQLKVPTV
GHLTLVGATQTELESVLKQYEALGLSGVLALRGDPVGGPAAEWTPTPGGFDYADQLVQLA
KTSTNLDIGVAAFPDVHPGSNGNFMQDIKVLLRKEELGATFAITQFVFDSGRFEALSDAL
VARGSKLRLYPGIMPVTNYTMILRMLELSGGYMPKATRLRFARYQNDVESLKALGIDIAV
QICEDVIALGADGLHFYTLNQSGPTKAVLDQISHF
>A0A2P8HW55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salsuginibacillus halophilus|TrEMBL
MKSLKEALNEQVLVGDGAMGTLLYERGCEGSFEALNVNRPLDVQAVHEAYVEAGADVLQT
NTYAANRVKLEKHGLEDEVKSMNRQGVKIAKTAADGQAYVLGTIGGIYGLSRADVSEVEV
EQAHREQVNVLLNEGVDGLLLETFYDLKEAENVVKAVREQSELPVIAQVSLGDVGVMKGG
LPLEDALKRLEAAGADVVGVNCRMGPYHILRSFETLPILQNAHFSAYPNASLPDYEDGRF
VYQSNPSYFYERALDFHKQGVRLIGGCCGTRPEHVKAISDAVKGATPVTEKSVVPTVPEP
AGTSAVSTAESLPEKVKREPTVIVELDPPKKPASLNKFLRGAEALHQAGADAVTLADNSL
ATPRVDNLAVGSMIQKETNARPLLHVACRDRNLIGQQSHLLGLHALGVQDVLAVTGDPTK
VGDFPGAASVYDLTSFDLISMMKEMNEGRSYSGKSLGEKTNFTIAAAFNPNVRGLERAVT
RLEKKIEAGADYFMTQPVYQKEKFADIYEATKHLSTPFFMGIMPLVNSRNAEFLHNEVPG
IKLTDEVREQMAACGEDREKSAETGLQLAKDLIDEALKYFNGVYLITPFLRYELTEELTR
YIKETQAGRKDVTS
>A0A6J6B0W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSVMREKLENSNETVFTAEFPSIDGGGMAKVEKSAARLAPWFDAVNATDNPAAHAHASNT
SSAIAMKMHGIEPIMQIVCRDKNRLAIQADMMGAALHGIENISLLTGDDVTAGDEPETRR
VFDIDSTQAINIARILTTGQYLSGRKINPAPDFYISAVENPAAPPFDYRIERALKKYRAG
AKYLQLQICYHPDRLEKFCAGVAKIAPDLKLIPTIVLVKSAKPMSFMNDKVPGIDIPLDS
INRVASATDQADEAYKLTLELAKHALSLPAVRGLHVTDFRHDDSLDSFMYDLGQKPRN
>A0A5C6TI59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. cubense|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGFTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHADYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDDVKGDDERVKMVGVDIVSELIDKIKTIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A4U0UQS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Friedmanniomyces endolithicus|TrEMBL
MDKITDKLAALPPDSHYFSLEFFPPKTQHGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRRLVDEALEQAKALGVRNILALRGDPPRSDE
YRDDSGDQEALEADDSNKDFMWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSV
EHDLPYLVEKAAAGADFIMTQLFYDVEAYTRYERRLREHESGLFKTIPIIPGLMPVQSYQ
ILRRTTKLSHAALPPAVLKRLETVKGDDEAVKRVGVDIITEAVEKMKSVPNPGPRGFHFY
TLNLEKVVTQILERSSLIPPATPIITMPDSNGGPDHAIAEEETDGFLIVERSKQNCNHRR
GSSVKNSQPRNRVVVSRDRASSTSSTHTSAFEAPEDEAGVPRDQTNSRANTLAISQGEGA
VGREATWDDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPGSIGDISTIFRNH
LEGKIDAIPWSEEALQAETLTIKQHLLALVEKGWWSVASQPAVNGKRSNDPVFGWGPKNG
FVFQKPFVELFLPASDWEVLRPKLDADEQVTYFAGNAAGDFVSTDEHSVNPVTWGTFTGK
EIITPTIIEAVSFRSWVEEAFGIWAEWQRVYKPGSESSRLLERVRKDYWLVNVIHHGYLE
EHALWERLLSA
>A0A5Q4FTL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitriliruptor sp|TrEMBL
MVDERVVASLERARFEIIPMKGVDDQLPFLPAGVTVTVTASPTKGLDATLELAERVAQRG
NPVVPHLSARLVEGREHLARILARLEALGVEEVFVPAGDTEIPAGPYEGAADLLEEMTDL
GHHLQRVGITGYPESHAFIPDATTIVEMTRKAPHATAIVSQICYDPTIIRSWVSEVRARG
VDLPIYLGVPGVIDRAKLLRVSLRVGLGDSIRYLRKQHEVATRLLTGYTPDELVGGLGDL
IDHPDARVAGWHLFTFNEVERTERWRQELLLSLRGAAL
>A0A143Z3A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus collinsii|TrEMBL
MKIESKFQKKKPVLSFEIFPPKRDKAIQNIDETLAILSELNPDFISVTFGAGGSHTNNQT
VELAKRIKHQYGIDPLVHLTCLNHSKFEICELLEELKDAEIDSILALRGDANPAVEAKKD
FRYASDLVKFIRQYGDFSISGACYPECHTESKNKVEDIAHLKEKVDSGVQHLISQLFFDN
NAFYSFQEHIQIAGMHVPVEAGIMPVINKAQIERMVTLCGASLPEKFSRVMHKYEDNKDA
LFDAGMAYAINQIVDLLAHDVDGIHIYTMNNPIVAKRICDGIKNLI
>A0A0S4I801|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. URMO17WK12:I11|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SQVQVPAAPHLSCVGDTKAELRALLAEYKQVGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEADLANFAHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEELLQGGAPSLHFYTLNQAEPSKAIWNNLQPSR
>A0A2X2JFI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella dysenteriae|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVPAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A328DS17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cuscuta australis|TrEMBL
MKVIEKIGELSKEENNGGKVVFSFEFFPPKTQDGVENLFERMERMVAHNPTFCDITWGAG
GSTADLTLEIASRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPH
GQDKFVQVEGGFSCALDLVKHIRDKYGDYFGITVAGYPETHPDVIPASGVATPEAYQNDL
AYLKRKVDAGADLIITQLFYDTDTFLKFVNDCRQIGITCPIVPGIMPINNYNGFIRMTGF
CKTKIPPEIMAALEPIRDNEEAVKAYGIHLATEMCKKIIASGIKTLHLYTLNMDKSALAI
LMNLGLIDESSISRSLPWRRPTNVFRTKEDVRPIFWANRPKSYISRTIGWDEYPQGRWGD
SRNPSYGALSDHQFMRPRARDKRFHDEWVVPLNTIEDICELFSKYCVGRVRSNPWSELDG
LQPETRFIDEKLADINKKGFLTINSQPAVNGAKSDSPSIGWGGPGGYVYQKAYLEFFCSR
QKLNALVDKCKCFPSLTYIAVDKEGTWVSNVKQTDVNAVTWGVFPAKEIVQPTIVDPASF
MIWKEEAFEAWSKCWGHLYPESDLSRKLLDEVESTYFLVSLVDNDYISGDLFGIFNDM
>A0A1J4NK42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. LCT-H3|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLADFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADNFDADIKRFCEKARAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A0J1BXH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria sp. SM24M-10|TrEMBL
MTPGGSVRRPPDRTAPPPSLSYELYPPRCAASAETLLRTIEELEPTRPDHVAVTYSGDAP
RRAGSLALLDHLLARTGLRPVAHLTCVGSTRAELEETVASLLHRGVRGVLALRGDLEPGT
EPGELAHAGDLVELVREVEQRRTASLAGGRLAVGVAAYPTRHPESPSFRHDIEVLLAKQR
AGADFAITQVYFRPQRYERLVASARAAGVTIPIVPGIMPVTEPRRLATLCRLAGLRPHPG
LAAALDEAAGPAERHRAGVAFATRLARAALDAGAPGLHLYTFNEHRAALDLLERVDLPRV
PHQPAALPDLLPA
>A0A2G5LCP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter sp. 4G9|TrEMBL
MKVTEHIEKAKGKTLFSFELIPPVKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
KGGLLEKKVTRMRPGTVGICSSIQHKYHVDTVPHLLCGGFTKEETEYVLVDCHYLGIDNV
MALRGDSMKEERYFTPTDGGHCYAKELVEQIRNLSHGQYLHETINSDDNADFCIGVAGYP
EKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVEAAKNLGINVPIIPGIKP
VAVKRHLQLLPQVFRIDIPQDLIDAVEACSTNKEVRQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAKEVF
>A0A668ULK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oreochromis aureus|TrEMBL
MVNQVQRGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQSKEKITGYLAKAKHLGLKNIMALRGDPVGEDWEEEEDGFNYAID
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNY
GIQQAVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELQNEESVFEVFTSYITAQPNHCGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVNVSFLGNVKPCLVLLND
>A0A440FS16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNFSQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDPIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A8J2Y8G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinithermofilum abyssi|TrEMBL
MTKAQLKKVLSETLLIGDGALSTYLYQQGIPVGVTAEELCLSQPEWIEEVHRSYYQAGAR
LIETNTYGANRERLARYGLEGKVTRINRESVAIARRAIGEDAFIFGSIGSICAGRVPNYS
RAEYRDMYEEQATALLYGGVDGLILETFLDLEELQLALEVIRPLTDLPVFCSMAQMEVGR
TRDGATLTEAFAELKRKGADGIGLNCRQGPLEIQRALEKTVVPEDVWLAVFPNAGRLGLA
DGEYQYKSTPDYFAERAEALREQGVHVIGGCCGTTPRHIEAMAERLAGRSPLPRINPEHP
LEAEKSRPRITVRNRPTVVEKVKKDTTIIVEFDSPKDLDVTEYLQGATALHQAGADAVTL
ADNSMATTRMSNMALGAILKNQTDVEPLVHITCRDRNLIGQQSHLMGLHALGIDQILVIT
GDPTRIGDLPGSSSVYDVTSFDLIRMVKQLNEGISFSGKPLKQKARFVVGAAFNPNVSKI
EAAVRRLEKKVEAGADFVMTQPVYDVESIQRVARAVRHIPIPVFIGIMPLTSHRNALFLH
NELPGVKIPDTVMERMNGLKGPQARDLGVTLAKDLLDEAVRHFNGIYLITPFAYWEMTAE
LTRYIREKQPARQVSGA
>A0A8B5EK68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. CH186|TrEMBL
MCNFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGSKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKPKAAIKIYEAVKHLLKEELHA
>A0A167GPI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dokdonella koreensis DS-123|TrEMBL
MTPISFEFFPPKTDDQRSTLEKTVAQLRPRAPQYVSMTFGAGGSTLSYTLEAVRELHVRH
GLDAAPHLSCMGGTRAEIRDLLQAYRALGVRRIVALRGDLPSGMASFGDLRYASDLVEFI
RAETGDHFHIEVACYPEVHPQAADAHADLAHFKRKIQAGADGAITQYFYNPDGYFRFVDA
ARRLGVDAPIVPGIMPIANFSQLRRFSELCGAEIPRWLTKRLAAFGDDADAIREFSADVV
ADLCRTLLERGAPGLHFYTLNRARPTLAVLERLDPAR
>A0A1A7BUJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium psychrotolerans|TrEMBL
MATHNFSIEFFPPKTPEGAEKLRATRARLSELQPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVNRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLQAFARKVQAGADAAITQYFYNADAYFQFVE
QTRKLGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTSLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A2M8CL81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium CG_4_9_14_3_um_filter_41_19|TrEMBL
MERTIIQYLAEAKKTLFSFELLPPLKGHNFDSIQQAIDPLVKFDPAFINITYHQQEVVYE
NLPNNLMKKHTVRKRPGTVGISAAIKYRFGIDVVPHIICGGFTREETENALIDLQFLDIN
NVLVVRGDPQPGTRIFVPEPDGNEHALDLVKQITNLNKGIYLDADLLNTRSMNFCIGVAG
YPEKHGESPNLDSDLYFLKKKIQAGASYIVTQMFFDNQKYFDFVARCREKGITVPIIPGL
KPFTTASQLTALPKTFNVDIPVDLVKEVIKCKNNQQVRQVGIEWAIQQSIELYAAGVPVL
HYYTMGKSDNIEEIAKAVF
>A0A528WK59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MSARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYC
>A0A528D5F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
CGVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVS
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMV
KTAH
>A0A529XTH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
QFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLCGVGPLASAKTAKWIRSNVPGIHIPDA
VIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAGIHVMAYRQEEYVAEIVDESGVLKG
>A0A2S0KKM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia iterans|TrEMBL
MGRVTAHSAESAGQPTVVERLAAPHSGPVPFSVEFFPPRSADEEARLWHAVRVFERMNPA
FVSLTYGAGGSTRDRTVRIAGELATSTTLTTVAHLTAVDHSVDELRGLVGAYADKGITNL
LALRGDPPGDPLGEWVAHPEGVQYANQLVELINSLGEFHTGVASFPEGHHRAPNLAADTG
NLVRKLRAGAEYSVTQIFFDVEHYLRLRDRVVAADPEQGAKPIIPGIMPITSLASVRRMV
ELSGSVLPAAVADRLAAAAGDGPEENREAVRAVGIDLCTEMSQRLISEGVPGLHFCSLNF
ARATSEVLERIGVDTRGALTPA
>A0A1G9BJ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentzea albidocapillata subsp. violacea|TrEMBL
MTSVVERLRGESPKFSVEFLPPRDAEDEKVLWKAVRELEGLDPAFVSITYGAGGSRRDRT
IRATGRIAQETTLLPVAHLTAVEHSVAELRNVIGWYAAIGVRNILALRGDPPGDPMGEWV
AHPEGLSYADELVRLVRELGDFCVGVAAFPYGHPRSGDLDTDLKFLLRKLNAGADYAVAQ
LFHAPEPFLRMRDRVAAAGCSAAILPGIMPMLSPRGLAKIVELSGADLPLDVSRRLEPYA
DDVAGFRATGIDIATEMCRRLLDEGVPALHFYTMNRSKATKEVLGRLGLVTRA
>A0A0A2A856|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus str. MIT 9302|TrEMBL
MKSKLQQTLEKKSKVITAELMPPRGGSPIRSLKIAQLLKDKVHAVNITDGSRAVMRMCSL
AMSKLLLENGIEPVMQISCRDRNKIALQSDILGANALGIRNILCITGDSVKAGDQQDAKA
VHEFESVRLLQQIQAFNKGIDPTLGELSDKKTFIFSGAAADPSSRNQRSVENRIRKKKEA
GAGFIQTQMVMEKENLIEFCENISNPLEIPVIAGVFLLKSYKNALFINKYVPGVNIPENI
LNRLKDAKDPLQEGIEIAAEQAHDFFNIANGIHLMAVKAEHLIPEILEKADLNLEY
>A0A562C8U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. J18|TrEMBL
MSPPHPLQPDENPAGVHLPLDPLPGHSSRGRLERILRRGEFAVTAELNPPDSANPEDVYE
RAAIFDGWVDGINAVDASGANCHMSSMGICALLTRMGYAPIMQIACRDRNRIAIQGDVLG
AAAMGVGNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRTMRDEQKFLSGRKLTTPPS
VFLGAAINPFAPPYDFRPLRLAKKIAAGAQFVQSQYCFDVPMLRTYMQRVRDLSLHEKCF
ILVGVGPLASAKTARWIRSNVPGIHIPDDVIKRLEGAQDQKKEGKQLCIDIINEVKEIEG
VSGIHVMAYRQEEFVAEIVHESGVLKGRRPWKREPRADDALVADRLDHILHDELTERPGE
MIRGAVE
>A0A439N4E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKAFMQSARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A2E7T9L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MQDIDNNSLESTIKQFIGDWTIEVTPGGAKKITDFREYLKPGTTVYITFLPGSDFSDTIH
TAHKLREDGMIPVPHLAARSIPSETWLTNHLEKMKRELTLDHVLLIGGGVSTPVGDFEDT
MQLLDTGLFEKFDINNIGVAGHPEGSPDISNDAIQSAMEWKNNYAARTGFSLYMTTQFIF
EATPVIEWEARISNSGNRLPIKVGVPGIATLKTLLNHARACGIGPSMRFLTRQARNVSKL
MHPISPDALILDLARHYAGRESSIAGIHVYPLGGLKKSAAWFSTVSDQEFEVDLAEKRLI
L
>A0A3S0ILH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenibacter aquaticus|TrEMBL
MKVTEHIKNAKGKTLFSFEIIPPLKGRSIQELYDNIDPLMEFNPPFIDVTTSREEYVYIE
RDGLLDKKLTRMRPGTVGICASIQHKYKVDTVPHLLCGGFTKEETEYVLVDCQYLGIENV
MALRGDAMKGEQYFSPTKGGHCYASDLVKQIYALNCGSYLHDRVEMVNKANFCIGVAGYP
EKHLEAPSLTTDLKRLKEKVDAGADYVVTQMFFDNQRYFEFVEAAREMGINVPIIPGIKP
IAVKRHLQLLPQVFKIDLPQDLIDAVDDCSNNAAVRQVGIEWAIQQSKELKEAGVPVLHY
YSMGKSDNVEAIAKGVF
>A0A0Q9EU02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. Root96|TrEMBL
MLPISFEFYPPKTDEQRAQLDKTAAKLKARKPHYVSCTFGAGGSTLSYTPDTVRHLRETH
SLDAAPHLSCVGGTRAEIRQLLSQYRDIGCRRLVTLRGDLPSGMASAGDLRYANELVEFI
RAETGDHFHIEVAAYPEMHPQARDAHSDLENFKRKVRAGANGAITQYFYNADAYFRFVDD
VRAAGIDIPIVPGIMPIANFSQLHRFSDLCGAEIPRWIQQRMMAYGDDADSLREFGADVV
AQLCRRLIEGGAPGLHFYTLNLSKPTLSVVSRLG
>A0A0M4D9K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces pristinaespiralis|TrEMBL
MLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVAPNFVSVTYGAGGSTRAGTVKATQE
IAADTTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHPEGV
RYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDEDTRHFVDKCRAGADYAITQMFFVPE
DYLRLRDRVSAAGCETPIIPEIMPVTSVKQIERFATLSNAHFPAELKERILAVKDDPAAV
RSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHEQS
>A0A5E9B4N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLERLKPEFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFVDFGVTRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>A0A531DF73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MTALQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAQRLDHILHDEITETQVDMVK
TAH
>A0A439UC92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A2D6CQ56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MHSVNSSDPGQPLPILEGHVSAGRLERVLRSGKFAVTAEIAPPDAADGEAVYRRASMFDG
CVDAINATDGSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVT
NILCLTGDGVQAGDQPDAKPVFDLDCISLLQTVTAMRDQGEFLSGRKLTTPPRVFLGAAA
NPFGPPLDYRPVRLEKKINAGAQFVQTQYCFDLERLRTYMMRVRDMGLTERCYILVGVGP
MPSARTAAWVRDNVPGVHIPDPVIKRLLDARDQREEGVRICVEIIQAVREIEGVHGIHIM
AYKQEERVREIVTESGVLEGRTPWYPGVGNDHCGQQK
>A0A1F5AJQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium RBG_16_63_16|TrEMBL
MKNRFIEAVADRVLLCDGAMGTMLYSKGIYINACFDELNVSHPELVRDIHREYVHAGVDL
VETNTFGANRHKLKKYGLDDRVREINLAGVLIAREEAGDEILVAGSIGPLGLKIEPWGQT
PVEDAEAAFREQAQALHEGGVDLFILETFSDVNEIHLAIKAVRSVSAGAVVVAEMTIGED
GNSLYGTTPEVFAGMLEDWTADVVGVNCSVGPAPMLHCIEKIARVTDLPLSAMPNAGLPQ
EVDGRNLYLCSPDYMAEYARRFIQAGVKLVGGCCGTTPAHIRAMRGAIRALRPPQRAAVT
VASRPADRKDETKTPLRDKSGLGRKLEEGCFIKCVEIVPPRGHDPLGAVEVVRMLERSRV
DCVNIPDGPRASSRMSPMALASILVAASKMEILLHYTCRDRNLLGMQSDLLGLSALNIRN
LLIITGDPPKLGDYPDATAVFDVDSIGLTKVVSSLNRGMDIGGRKMGTPTSFLIGVGVNP
AAVQLDHEIRRLEAKVEAGAEFAITQPIFDVRVLDNFLSRIQRLRLPVLAGIWPLWSLRN
AEFLKNEVPGTAVPDEVIARMCRAQDAGPERARQEGVELACEILLAVKGMVQGIQVSPPL
GKYEVVLQVLKTV
>A0A5E7R4X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAKYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLKQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>W4GLK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces astaci|TrEMBL
MGKIIDRLTELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPREQLREILKNVRAAGIRNILALRGDPPIGSE
RWKAIPGGFQNAVELIRFIREEHGDWFCIAAAGYAEVHTEAWNNPNLPPSDQVRRVDMLR
LKEKQDAGADFIITQFFFDVDKLLQWIRDCRQVGITIPILPGYLPIQTYNSFLKFTNWCK
TSVPPQVEDALVTIKNDDSAVKKYGIQLAVDTCRKLLANNLSLHFYTMNLATTVRTVLEG
LHLIERERGLPWGAPITRSKDGTLEKSIEQVRPIFWSNRASSYIARTSEWDDFPNGRWGD
RTSPAYGELSEYYLAYKRPKVARDALWGRPQTEQDVWNVFVKFIEGSVKQLPWCEQGLSG
ESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPHLM
QRLVVALADYPNLSYHAFSANGTEYTNSPGPSVTAVTWGVFPGKEIIQPTVVDTASFAAW
KDEAFELWLSQWASAYETDSPSHQLIKRIFDSYVLVNVVDNDYTNGTVLLL
>A0A1C7LLQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grifola frondosa|TrEMBL
MDIPLSSLFHRALTTASKAFNLPTIEDDTQELISALSDLLLVNSRVSALSLFSTNEQLSD
IATRDLIYLLVPFAFAEVESRARTVDMDERLQRVVRAQTYLRTFTASLETHEIVPESEKV
LYAQRTSSVNDPTKRRELKIRQYKQEKDIRTKIDAVRKRRNQNLVSSEPTTDFELVASLL
PDPVHVSSTAGDEEDDADTEDILREATLLLLRLTYAQAHTQLESMEQELELLRNAPPPPP
SQSPLHDPRAAKERETSDMWRLDAPLPPGGPDGKGPLLDSTGKPLRPFTILPAGASDRAR
LQGQVFQSDHRLPTMSVDEYLKIEAQRGNIISGDGPQSESQLTTSEQLALDAEMEVPRLG
FENLLSRISRLLALNPLAITVTWVWGTTKERSLDLAGEEGGCRVADAKERGIQNILALRG
DPPRGEEYWIPTDPRFTHGIDLVTYIKSSPEFSSDFCIGVAAYPDGHPDKDKDEEGELNY
LKAKIDAGAEFIITQLFYDVEGFLRWVKKVREKGIQVPIIPGIMPIQTYASFLRVTKLCG
TRVPSSLMSDLVPIRHDDQKVKDYGVQLAVDMIKRLTTEGDIRGVHFCTLNLEKSVTRVL
EALAGLAEDTEEPPESERIITPHTATDTAATKLATSGPNTEVEAGKGELNSAADWDDFPN
GRFGDFKSPAYGETDPWVAFIPRLDLASASARTVGVSEDRRRSHGAFLRHIHSKLATTPF
SHTPLSPESLLIFPHLERLTRKGWWTVGSQPAIDGASSMDEVVGWGPRGGYVYQKCFVEF
FVEKQDAERIVQKVEQEGQGLVSYFAGNVLGECLTNVPEGERNAVTWVSFPARKLHRQPS
SKGSLSLHGRIGILDLAEWASFYPPDSEERRLLESVRNERWLVSIIHHDYMDPAALWHFL
FKGTPLV
>A0A7Z9SZJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRFRDKVRKPKRPVVAYEILPPREQDGTLNSYAEKISSLLSQTHIDAINIPEVHDESVRG
KRPVKNQKRAEAREFGRLLQDNVGIEAIVNRVTVNHELNYQKNWIKETYYDYDIENLILV
GGESSKINYPGPSVNNTSEYITRDLNTGRFDFFCGGITIPSRKTESAKLFRKGSNGIEFF
TSQVLYNGNKIKKMLKHYDDICEKNGVMPRRILLSFAPVSSKKNIDFLKWLGVEIPENTE
HRLNQDPENMSNVSLEIASEILKDILQNNEEKEITVPIGLNVEHIMSYNFQSSINMLQKL
SRIYREFCIKTSLYD
>A0A7Z2TEC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGEHFHVEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A5E7D7D1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VDFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A149QLR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. DDT-1|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCHRLVALRGDLPSGMGFPGDMRYAAELIEFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFYNPDAYFHFVDA
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLVEGGAPGLHFYTLNLAKPTTSVLKLLHG
>A0A2D7IIR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIRDKIKKPQRPVVAYEILPPREKDGTLNAYAETISSLLSQTHIDAINIPEVHDEVGRG
ERPVSNQERGEPRKFGMLLQDIVGIEAIVNRVVVHMSLKKQMEWIKETYSKYEIDNLIIV
GGESSKQEYPGPTVNESLEKISQDNRSLENSILCGGICIPSRRKESKNLIRKSECGAEFF
TTQVLCDSSNVIKMIKNYQERCDKVNTFPRRILLSFAPVSSQKNIDFLKWLGVEIPKDTE
RYLNGRPGAMMERSLDVAIEVLNEILAFIANNNLKVPVGLNVEHIMSYNFQSSVEMLQEL
ANIYRKFCINTQQYN
>A0A2S2DJY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia oculi|TrEMBL
METPDFSIEFFPPKTPEGAEKLRIARAKLAELNPKYFSVTFGAGGSTQQGTLATVREIQA
AGHEAAPHLSCIGATRESIRDVLKQYQDSGIRRVVALRGDLPSGYGGAGELRYASELVEF
IRQETGDWFHIEVAAYPEMHPQARSPQDDLQAFARKVGAGANAAITQYFYNADAYFQFVD
NVRKLGIDVPVVAGIMPITNTMQLLRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLAGGAPGLHFYSMNQAAPTTAIWQRLRA
>S0P0Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus sulfureus ATCC 49903|TrEMBL
MRIDHLFQEKTVFSYEVFPPKTNSSLETIYTTLDRLKGQQPDFISVTLGAGGSAKNLQTV
EIAQKIQEEQFLPSVAHLPAVHFTKAEIKLILDQLQAKKVENILALRGDILPGQTPKGDF
EHATQLVEFIKEHGSFNIIGACYPETHVEACNAIEDIRFLKEKVDAGTNQLVSQLFFDNQ
YFYRFLERCALARIDVPIQAGIMPVVNKKQIERIAKMSHVTLPEKFLKMMARYEHNPEAI
RDAGIAYAVDQIVDLVAQGVDGIHLYTMNNPYVAKRIREATRSLFEQAPLTLIAE
>A0A448BWS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNPQLPR
>A0A149QMG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. DDT-1|TrEMBL
MPAGLSLRADAFINAFSLEVSAKAMPALCAEADRIPCGTVISIPWLASEDDDARLAAART
VRALGFEPMPHLSARRVGSRAALERFLQRAASEARVARCLLIAGDLATPVGPFADSASII
QTGVLEQSGIKVVAIGGHPEGHPVMSSDERWQALEGKCQAIEARGMAPLVVTQFAFDADT
VLAWLDALRARGITAPVLVGVPGPASIPRLMRYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVKGLTSAHGPVSPHFFPFGGVAPSLEWMAQYRRRISGTGG
>A0A1Q8AE83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_1_20CM_2_65_11|TrEMBL
MHIAEMLDRGRPTVSFEFMAPRDENEVQVLEKTVAALAGHAPDWVSVTYRLRTGQETLEL
VTRIKRQYHIEAMAHLTCANTRDATRRILNWMEREGIANVLALRGDPPGPGQPFQPADAG
LTHGSDLVAFVRGNGYRLGIGAACSAEKHPESPDLEHEFHYMRLKVEAGADFLITQLFFD
NRFYFDLVARARTAGIKVPIVPGLMPLPSRRSLAFVTEMSGASVPEPLQRAIDAQPDDEG
IRKLGVEHCIRQCVELLEAGVPGLHFYTFNRARAPIEILGALRGQQLLAS
>A0A1Q3H4A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine bacterium AO1-C|TrEMBL
MTKIIEYIKNSEKTLFSFEIIPPLKGQSIQSLFNAIEPLMEFKPKFIDVTYHREEYVYRN
RGEGLLEKHVTRKRPGTVGICAAIMHHFQVDAVPHLICGGFNKEETENALIDLNFLGVDN
VLVLRGDAIKSEGRFHADPNGHKYASELLDQVVKMNNGVYMDEELKNPYPSNFCIGVAGY
PEKHFEAPNFTTDMKYLKMKVDMGAEYIVTQMFFDNQKYFDFVKKCRESGIDVPIIPGLK
PLTSSKQLTILPSIFHIDLPQDLVDAVTKCKNNDDVRQVGIEWGIQQSKELIDFGVPVLH
YYSMSRSKAVKEIASALF
>A0A2P8GWA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labedella gwakjiensis|TrEMBL
MSIPADGASGAAVPLGFPVSFELFPPRTDAAAIALGRTIDRLAEFDPAFISVTFGAGGSS
RDRSLTVLRYILEHTTVEPMAHLTCVGSTHAEANRLVREFLDAGVTSFLALRGDPPKDGD
GALGDLGSAAELVQLIHRVQEEREPFTLQPVPGAAAGRIRRRPRPERVAVAAFPTGHPRS
RDVARDVDALLAKQVAGANLAITQIFFRAPDYLAFVDRARAAGVTIPILPGIMPITTPER
LHRVGEMTGEEPPSSLAIDLEIEPTEEGRTAAGVAFASALSSAVLDGGAPGLHLYTFNRY
QEVRSVLETVARTRPHALPLPDTTPPEKTPTKDPR
>A0A5E6Q546|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRDLLAQYKSAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETADHFHIEVAAYPEMHPQARNFEDDLANFVRKANAGANSAITQYFFNADSYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A2E1ZWR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MLKILDILSNKQTISFEFFPPRREEGIPDVVDKMKMLSDYAPDFISVTYGAGGSTQNFTE
ELSRIAKADLNLEVMSHITCVGQTSTEIDLVLNRLKNNNIDNIIGLRGDPPKGSNKFVPT
DGGXQYASQLINHINNHFDFCVAAAAYPESHTESINPKSDIEHLKEKVDMGVDFLITQLF
FDNNYYYDFVERARAAGIHIPIIPALLPILNASQIRRFTTLCGASIPTDLNSLLTQMEDN
DDQVIQLGIDYATQQAENLLSNKVPGIHFYVLNKNYSVQKILKNLNLVPH
>A0A2D8VQ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVTDFLENKNKTHFSFEIIPPFRGGSIDKVFSLVEDLMRFDPPFIDLTSRSAEEYYXDD
GDGNLVQHIRRKRPGTIGMSAAIKNKFNVETVPHLLCSGFSKEETEDALIELNYLGIKNV
LAVRGDELRNDXNLSKSKNSNFYASDLVKQIKDMNEGRYLEPLIDPFKSDFCIGVGGYPE
KHFEAIDLKSDISRLKEKVDSGADXIVTQMFFDNKVYFDFVDKCRDEGIEIPIIPGIKIL
STEKHLTALPKHFFIDLPKELKDSIQAKTKNEIRNAGKKWAVKQIQELIERDAPCIHLYI
MASSKLASEVVSEFI
>A0A0D0PGF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASHKPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VSFIREETGDHFHIEIAAYPEMHPQARNFEDDLRNFVRKAHAGANSAITQYFFNADSYFY
FVERVRQLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EDVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A2E7SUC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MYEILPPREKDGTLNSYAEIISSLLSQTHIDAINIPEVRDESMRGARPVKNKTRAEPREF
GKLLQDIVGIEAIVNRVVVHQPIEEEINWIEETYKIYEIENLIVVGGESSKINYIGSTVN
SALRAINSRIDTNGCDIFCGGITIPSRLKESKSLINKSKXGSXFFTTQVLYDSSKIKRMM
SHYQVRCNKTNTFPRRLLLSFAPVSSQKNIEFLKWLGVEIPNKTESYLKGHPASMIERSL
NVAVGVLNETLDHIKENDLTVPIGLNVEHIMSYNFQASVEMLQELARIYREFCIKTENY
>A0A367G334|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia obeum|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVQLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAEI
>A0A2N2RB78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-3|TrEMBL
MNTPTRFPVSFEFFPPKTPEGATKLAAVRQQLYALKPEFFSVTYGAGGSTQDGTLQTVQA
ILADGHVAAPHFSCIGATRESVRAQLQRFQQAGIRRVVALRGDLPSGYGAFGEFRYASEL
VAFIREETGDAFHIEVGCYPETHPQAKSPEADLQAFAAKVAAGASSAITQYFYNADAYAR
FVDDARRLGVKVAVVPGVMPITSSTQLMRFSDACGAEIPRWIRQRLMAYGDDSASIKAFG
LDVVSALCEQLRRAGAPGLHFYTMNQAVATTAIVQRLGLA
>A0A841ACH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium aquaticum|TrEMBL
MADDRARLARVQFEVLPLPGILEQVPVHLPPGARVTVTASPAQGLDATLETAGALARAGY
VAIPHLASRMVPGPEALDDILDRLAADGIGEVFVIAGDAPQPAGPYDGALALLEALVPRE
RGLTAGIGVHPEGHPFLGEAQARELLARKAEHASYLVTQMLFDASTLAAWVAQLREDGIG
LPVRPGIAGPASRARLLRVGARIGVGRSLRMLTAEGSGVRRLLSPGHWDGDELLEALEAA
GIDALAAPHVYTFNALEASARWWGARGT
>M5REV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus stratosphericus LAMA 585|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSLDEIKR
SFREQLYILLNEEPDGLLLETYYDIEEAKAVLEIARKETALPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPLLENSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHISAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKSAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIREIMAKAGEDKEKQRTEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKEPNIHANYH
>A0A6I0FKC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. 366|TrEMBL
MPPVSRQVAVSQAISSQVPGRIPFSVEFMPPRDDAAEERLWNCAEAFHDLGVSFCSITYG
AGGSTQERTLRVASQLAAKPLTTLMHMTLVGHRRDELVELIETFAKEGLSNLLALRGDPP
GDPNAEWIPTEGGFTHAVELIELVKQTEATQHFDIGIASFPQGHYRAIDLEHDTKYTLEK
LRAGAEFSITQMFFDVDDYLRLRDRLAAADPEFGAKPIIPGLMPITSIRGVRRQMELAGC
SLPKPLEERLMKAAAGDEVGNAAAVREVGIEITTAMAERLISEGAPDLHFMTMNNVHATQ
DVLHNLGMAPAWGPDLGHDAVR
>A0A7G8F851|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. MVIR-18-1|TrEMBL
MSSALQSSLEAGTVTITAEVMPPRGGDPSHALEMARVLKGHVHAVNVTDGSRAVMRMSSL
ALARLLLDEGIEPVLQMACRDRNRIAIQADLLGAHALGIRNLLCLTGDPVRAGDQPKARP
VNELESVRLLQQVTSFNRGDDPVKGQLADGATDIFAGAAADPQCASWSGLVRRMQRKKAA
GARFIQTQMVMDAAVLERFCREIAEPMQLPVLAGVFLLKSARNASFINRMVPGACIPENL
IARLKAAADPAAEGIQIAAEQVQQYLGVAQGVHLMAIKAEERIPAILKQAGVSLPG
>A0A855MQZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrotoga sibirica DSM 13575|TrEMBL
MKIIDLIKQSIKPILSFEIIPPNVGESIDPIFNVVDNLIDFSPKFINVTKHANEIEYVEE
NGEIIKIIKKKRPGTVGVSASIKHRYDIEVVPHLICTGFNKYQIEDILIDLNYLRIENIF
VVRGDKKRYTWKETDEYEHATQLVEQVTNMNKGIYTCPTKEHNPTNFCIGVAGYPEKHFE
SPNLEKDLDYLKLKVDIGAEFIITQMFFDIEYYKNFVNKVRELGIEVPIIPGIKPLGSKK
TLYNIPKTFHVNIPKTIVEEFEDAKSFQDEYIIGVRHGIKLIEQLLELRVPGIHLFTMGK
GKIVKDILSAFKGIF
>A0A2B5HQK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pseudomycoides|TrEMBL
MKILDLVSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADIIQTN
TYGANEAKLRMYGLENQVTQINKAAVKLAKAAVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEKVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQLALHEAGTTQNGN
DVNGILTQFLDYGANIVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPAHIEGMKRVIANVTPVTEKQIVQRQQVVH
IQTKRASTHVTLAEKARKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSAIELIKMIKEMNDGRSILGKSIGPATRFSIGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIEEIYEATKHLEKPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMDGHETQESAIEEGIRISQELINEAMKYFNGIYLITPFLKYEITENLVKYVK
EKQEVKEGIN
>A0A6N1XHM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dechloromonas sp|TrEMBL
MKPEISIEFFPPQTPEGIXKLRTVRARLAELKPSFFSVTFGVSGSTRERTFAVVKEIAAE
GYDAAPHLSCIGSTRDNIRDILNEYKAAGIRRTVALRGDLPSGMAETGEFRYANELVEFI
RAETGDWFSIEVAAYPEWHPQARSPKDDLDAFVRKVKAGANSAITQYFYNADAYFHFVDX
ARALGVDVPIVPGIMPIAGFTKLARFSDACGAELPRWMRRKFEXFGDDADSIRAFGLDVV
TELCERLLKGGAPGLHFYCMNQSALTTEICRRLD
>A0A3C1ZLB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerochaeta sp|TrEMBL
MQVIDILRQAKRPLFTFELVPPLKGGDVQTLLETVRQLSQFEPAYINVTNHQQEVVYLER
PDGLLERRTVRKRPGTIALSALIQYTFNIPVVAHLICGGMDRDQLEDALVELNFLGIENV
LALRGDPPNGEKRFVPVKGGYEHSSELVSQINDLNMGRYLDQNLQNARKTHFCIGVAGYP
EKHAEAPNLERDIEMLKHKVDSGAHYIVTQMFFDNAVYYRFVDACRKAGITVPIIPGLKP
IGSKRDLATIPQTFHVDFPSELVEQLTKATKLAEIHEIGVHWCTLQTKDLLAHGAPSVHF
YTLGKAESVASVVRSCY
>A0A0R0DVJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas daejeonensis|TrEMBL
MTALSFEFYPPKTDDQRAQLDRAANKLKVHAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTREEIRELLKLYRAIGVKRIVALRGDLPSGMGFPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAGDALADLRHFKAKVDAGADAAITQYFYNADAYFRFVDD
VRRLGVDIPIIPGVMPISNFSQLRRFSEQCGAEIPRWIGKRMQAYGDDAESVRAFGADVV
AALCERLSAGGAPSLHFYTLNLAKPTGAVLQRLGRA
>A0A176QAZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janibacter melonis|TrEMBL
MVAAMTSPSAPSGTIPQRLSSTRPSISFEFMPPKDDAGEAVLWEAIARLEPFAPDFVSVT
YGAGGSSQDRTLRVTEQIGQRTSLTAMAHLTCVSQSVDDLREVLAGYAAACIDHVLALRG
DPPGDPGGEWTAHPQGLDHAEDLVALVREVGGFEVGVAAFPDVHPSSASLRDDVETLVRK
ADAGASFAVTQMVFDAESYLRLRDEVAARRDLPITPGLMPVTSVKQIRRMAQLMGTPLPA
AVVDRLQAVDGDPAAVRAVGVEIATELADRMLGEGAPGLHLITMNRSTASLEVLQNLSHL
RA
>A0A3A9HUE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyramidobacter sp. CG50-2|TrEMBL
MNNAFEEMLPNFSFEIFPPKRTGSLESIYDTVDALASLRPDLISVTYGAGGSNRDNTIEI
ASTIQNRYMLPAVAHLTCVGSSLEQTDALLAELKEKGVRTILALRGDRRADADFGDGYFK
HAAELVAHIKKNYDFRVLGACYPEKHPEAPSLEADIAHLKEKVDAGVDALITQLFLNNDD
FYRFRDLAQKAGVNVPIIAGIMPITQASMLDKVVSLCGASIPPAVRRFVDAYGHNAEAVR
EAGIAYAASQIVDLLASGVEGIHIYSMNKAGVTRQIAQNIHGILYSLRVKRS
>R5X2Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. CAG:257|TrEMBL
MASVKLSDMMKKRQLLSFELFPPKTDRGMANLSETIQQLCRYKPEYISVTYGAGGGNVGA
NREVCRMVRNAGTVPVTHFTVIRNTKQGIREQLETYLKEGVDHILALRGDFPRGETSTGG
DFNYATDLVKFIRDEFGEQFEIAVAGSPEGHISCRSLEADIGVLKMKQDNGADYIMTQLC
WDMEQFERWLDKIRRAGVTLPVDVGIMPILDQAATINMALSRNGCVMDRELSRLISKYWI
FPNPFDKAPFDDSLEQKKADFKKAGIEYTIRQIDKYRSLGVEGIHLYAMNKWKDVSQIIE
RSGIRTLI
>A0A395NPE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma arundinaceum|TrEMBL
MHIKSLVADTEKSKAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGLEKVNDALQKAYKAGCTNILALRGDPPRDQES
WTAADGNFQYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDMGAGF
IVTQMFYDADNFIRWVGKVRERGITIPILPGIMPIATYASFLRRAKHMQCRVPPEWMTLL
EPVKNDDVAVREIGKTLVADLCKKLLANGIHHLHFYTMNLAQATRMVLDELNWTPSAERP
LKQALPWKQSKGFGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPQSIQDIANTFVKYLEKKIETLPWSESALAAEADPIRDDLVA
LNKRGLLTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLMPPYLLDEMISRLDDFP
NLTYYAVTKDGELRSNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFDANSPSRALIEGIMNGWYLVNIVNNDFRENSTIFGFLQGLEVKDLAVPATGTA
>A0A395NC16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma arundinaceum|TrEMBL
MDRITDKIAALPADGEYFSLEFFPPKTQMGFSNLRVRLQRMERALRPLFVNVTWGAGGST
SQKSIELAELCQRELGLTTCLHLTCTNMSQSMIDQALEDARALGIRNILALRGDPPRAEY
RDADEPAQASEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPYL
VDKVQAGADFIMTQLFFDIEAYNKFETTLRHHPSGAFKTIPILPGLMPIQSYAMIKRTAK
LSHAKMPDEIMARLNAVKGDDEKVKMVGVDILGELVEQIREVKSRTPGPKGFHFYTLNLE
KSIAFILERTKLIPDVPEDEEAVIDEPVTTAAAQLPIPKISVNGNVPPRRGSHSRTARRQ
SSVGSDPHNRVIVGRAATHPEWEATSTEAGIPAENVNTRANTLAISEGEGALGREATWDD
FPNGRFGDARSPAYGEIDGYGVSIHMSVTQAVSLWGYPKTASDINDIFVRHIKGEVSAIP
WSEEDLLPESFIIKSSLEAMNRKGWWTVASQPAVNGLPSTDATFGWGPSSGFVFQKSFVE
FFLPAADWKILYDKLTSSEVEEVVCFYASNAKGDFVSSDSTGGSGRAAVSASTNAVTWGV
FPGKEIVTPTIIEEVSFRAWSEEAFDIWAEWAKVYGRGSDSQKLLDGIREDRWLVNIIHH
DYVDTDALWRLLTN
>A0A1X4N7Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marivita geojedonensis|TrEMBL
MKRSARILQPKEALLKRLFESAGAVPLSFEVFPPGNEEQRKKLLETVDRLTPAAAQGFSV
TMGAGGTSRTGTYETAVEIAERTNRPVTAHLTAIGLSTNQAMETADALWSAGITRVLALR
GDALTPNNQPSLSGFKYAADLVRALADQHRFEISVAAYPEKHPEADDLDVDIDHLEEKLD
AGATRAYCQFVLDPSAYGRFLDKCSARGITADIIPGVMPLDGWSRLKRFAKKTETKVPLW
LSRLFACGEETPELMPLLASAATVEQARRLIAYGAPELHVYTMNRWPQSLTLAKLLGS
>A0A1V2P1H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sp. ALI-6-A|TrEMBL
MVNGFPSTLPGSTPTIRELLATGDPSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTAVAHSRDELRSVVGAYAGAGIRNVLALR
GDPPGGPRQPWVAHPEGLNHAIELVELVKSLGDFCVGVAAFPDKHPEAADLDFDARVLAA
KAEAGADYAITQMFFGADDYFRLVDRASALGCEIPILPGIMPVTNIKQIHRMAELTGMAL
PTAVTDRLHAVEDDPAAVREVGIEIASELCDKLLTGGAPGIHFITLNRSTATRQVYLNLQ
GTTV
>A0A2S8W2H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. MYb78|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1F9GJQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFCSPLOWO2_01_FULL_45_74|TrEMBL
MDKPFLEKLSEEGVLGDGAMGTEIYGRGIFLNRNYDELNLSSPTLIRDIHLDYLNAGAQV
LETNTFTANRPALAAFGFENKVKEINRAGAKIAKDAAKGQAYIAGAVGPVSWTFKQASVL
GDNDIKAIFAEQIQGLVEGGVDLIILETFLNLDELKLAYEAARSVKKNLPIVTQVTLKYE
GEEGFKGIQPAEACRLMCGWGADVVGVNCCTGPVGVLEAIKLMTPVATKPLSAFPNAGLP
QVKQNRLLYLATPEYMAEFARRLVQAGAHLVGGCCGTTPEMIKEMKRYLKTLRPTKRIES
IITLTPTEEIKKITPMPVEKRSAFGAILGKKFAVSVEIDPPKGLDASRAIEGAKFLKEHG
VDVINIADGPRAMARMSPIAMSVLIKQQLGMETVIHYCCRDRNLLGMQMDLIGANAVGLK
NILVITGDPPKMGEYPDATAVFDVDAIGLIHFINNLNHGLDFANRPIGEATSLVIGCGCN
PGAIDMDIEVERLRKKIEAGAEFIFSQPVYESKLLDKFLAKSRSFLKIPFFVGILPLASL
KNAEFLHNEVPGMQVPNSVMDQLKKAATKEAQREIGLKVAQEALKEAHDMTGVKGVYIFP
PFGKYEAVLELLKVIQ
>A0A2T7SY78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. Rim28|TrEMBL
MSGLKLPISLEFFPPKTPEGTEKLRGVREKLYALKPEFCSVTYGAGGSTQEGTFATVNAI
QSEGVAAASHFSCIGASKASVRAELATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLV
AFIRAETGDDFHIEVAAYPEIHPQAKSPEADLQAFATKVKAGADSAITQYFYNSDAYFRF
VDDAYKLGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQAYGDDIASIKAFGL
DVVSDLCEQLLNGGVPAIHFYTMNQSAPTLDIVGRLKSGL
>A0A164YC59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Daphnia magna|TrEMBL
MKPKIDYNSDGGLCSSSTSVSGEDTPNRDERCQSPTDFDYTSGNKSLAEKIRLRIESGEK
FFSLEFFPPRTKEGAVNLLARFERLRLACPLFCDVTWHPAGNPGGDTETSSMTIASAALN
YCGLETMLHLTCCNLSLEDVIKHLNRAREMGIRSILALRGDPPIGQDWHPPENGLKYAVD
LVRLIRNLFGDDFSICVAGYPTGHPDATSYEADLLHLKEKVDAGADFIITQLFFRAETFI
KFVRDCRALGINVPIIPGVMPIQSYDSLRQIAKLSKLEVPEEIINIVAPLKDNDEAIRNY
GVQQAVSLIRELFNAGLAPGVHFYTLNREVATTTILKQLGLWVTEPRRPLPWRRAANAKR
STETVRPIFWSSRPKAYIYRTRHWDEFPNGRWGKSDSPAFGELKDYYLFYLKSKSSKNDL
LRMWGEELCSEQDVWDVFHCYLSGQPNKCGVKITKIAWNDEELSSETSLLQEKLSEFNKK
GVLTINSQPNVNGAPSDDPVVGWGPRGGYVYQKAYLEFFTCQANVQALLKVLPSFPRVNF
HIINSNGSADYTNCHRHRPVAVTWGVFPGREVLQPTVVDPVSFKVWKDEAFALWREQWGK
LYPEGSTSRDLLTRISETYYLVNLVDNDFPRESCLWELLNAMFAQRELDNMSDFIQQDSD
VHLDAVDHYENGLRLTRRQDSQGDGSYTHYTMEELVEAAHRQEMHDEIVTGEGHQ
>D8MKP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erwinia billingiae (strain Eb661)|TrEMBL
MSFFHANQRDALNQNLAELNGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGADLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMTSMFE
GLDDDPETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPRGAVV
>N9MX72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 64.2|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKTVHQELQLLNPEFFSITYGAGGSTRERTLAAINEFN
GKGTPVAPHLSCIGDDKVRIAELLDLYRSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAETFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A7K7S432|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nesospiza acunhae|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRRVLQGRRGEVFDHMGAGGPLFIDVTWHPAGDPGSDKETS
SMIIAYTAVNYCGLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEE
VDGFNYAVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVYAGADFIITQ
LFFRPETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIK
DNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLP
WAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYL
KSKSPREELLKMWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLK
DQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVRALLKV
LRKYELRVNYHIVNVKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAF
ALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLD
>A0A168P7Y3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus antarcticus|TrEMBL
MKPDLRKAWENNVLIGDGAMGTFLYQMGFPVGISYEELNLTAPEVIKDVHRRYVEVGAQV
LESNTFSANFDKLSKYGLESKVEEINRAGVRIARDAAGPDGYVLGAVGSIRGGKRTNVST
KKLKLYFEQQITALLAEGVDGILLESFYDVEELSIALSRVRKLSDLPVVCQFAVEDVART
LDGYTMTEALHILQQEGADVIGFNCRTGPNGMMRAVESLGNQLSVPVSVFPNAGVADYVD
GEVRYTATPEYFGTMALRFADLGVRIIGGCCGTTPEHIKEISKALTGYVPSPIDKNIVLT
IPTPRVVHELTIDDAEDREPTIVDLVKQRHTVIVELDPPRDLDIKKFMLGAESLKKAGCD
ALTLADNSLAVTRMSNMALGYLIQDQTGMRPLIHIACRDRNLIGTQSHLMGFDALGIDHV
LAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKANFVVGAAFNPN
VKHLDKAVQRLEKKIAAGADYIMTQPVYDPKLIGAIKEATAHLDTPIFLGIMPLASGRNA
EYLHNEVPGIQLSEEVRARMVGLEGEEGRAMGVTIAKELIDEAMKHFNGIYIMTPFMFYG
MSVELTEYVWKRSGREVTPLFRS
>A0A7C2W5K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomicrobia archaeon|TrEMBL
MAKERKAFSNLMKAIERGEFVYTGELEPHRSIDLSDVKDWATTLKNTGKIVAANVTDNPR
SDSAISSLVAAYLIQRDVGLETIYQLRTADRNRLALLSDILGAAALGLKNILALTGDHTK
IGTTPAAKPVFDLDGTQLVALIHSLVYEGKDLDGNEIHGPKPEINVGVAGNPNMDPLEAE
VLKLERKAEVGADFVQTQVVFDVEIARKYLRAVEHIGIPVLIGIFPPRSYGQASFFDKYV
PGVTVPKEFIEAFKKFNEIEDKARRKEKINEYNVEYFVNFIKEVKKEKACAGIHIMAVGY
PDVIGPIIEGVEK
>A0A496UIR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Fermentibacteria bacterium|TrEMBL
MNLLNDGKIHLADGAIGEYLFSLGYPGNYLACEAVIRSPEILASIHREYASAGAVILTAD
TFDANTEKLDRHGLADRCEEINYRAVKLAARNGQCAVMGSIGPPGTGRSFHAEPGDTDRL
TETYAPQVAGLLSGGVDLILLETQIDPVQARIIYDIVRSCSGDIPVAVSFTYGHDLLTPS
GYSIKDSISEFADTDIVMLGANHGIGPLQFLDIHRRFAASSPFPVILQPNAGTGKYKNGR
FVFPENPDHFCRCMLSCTGKSTSLLGGCCGTTPAFISSLSRKLSEGAEIRVFSSPNPDEA
DDIPHSAVSYDPPSLSAQIAVGDALILELLPPRGGDLSLFSSRAEKLERFAPVTISIPDS
PMGKVRMSPCISGLYLREKLGIDPLVHFALRDRSLTRIQSDLLALSGAGLQGIFLISGDP
PSLGDYPESTAVYDLTTEQTLELLQHLADGQDLSGRKIGTGSGFFPGSAVALGDPDSADK
VRRRWDAGCRFFITQPVFSMETLERSAALLEEYPVLPAVMPFRNRYSAEYLASEVPGISI
PDQVLAKVHELDDCDVLSFSLDYLSRLIDGMRNMVSGVYMAGSRKGMMKLAEEWRE
>A0A6N9LEP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. BIOML-A1|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSVGMVRFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPELLKLAEL
>A0A842P8F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomicrobia archaeon|TrEMBL
MKAYSNLMQELLNGKFVFTGELEPEKTTDLTELVEGAKPLVGYAVACNVTDNPQSMAYMS
SLVASYVVQRDAGMEVVYQLRCSDRNRLALTGDVLGAAALGLKNILALTGDHVSLGDNPG
AKSVCDLDSALLTYMIRRMVDEGVDLAEKPIHEPPKLHVGVAVNPNADPLEAEVMKLKRK
EVAGAEFAQTQVIYEMEKVDRLFEVYDQYGIKVPVIIGIFPMKNYGVADYFDKNIPGVSV
PKELLETFRKVTEISDKKQRKEKYMEINLEYFENFVRDIKKSEAKGVHVMAVGYEVMVRE
LIGRVRGEG
>A0A379MTW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rikenella microfusus|TrEMBL
MKITDKFKPGKTLFAFELLPPLKGDNIDTIFDTIGRLAPYNPSYINVTYHREEVKLIERP
DGLLERRVVRKRPGTVGIAAAITARYGIDVAPHLICGGFSKFDIEDALIDLSFLGIDNVL
ALRGDNIRGERTFRPAPGGHPHACDLVSQIMNMNRGEYLDSELEHAKPTSFCIGVAGYPE
KHAEAPNLAADIAHLKTKIDAGASYVVTQMFFDNAKYFAYVDACRAAGITVPIVAGLKPF
TTKTQLSLLPQTFGVELPDDLVRAVENCKDNAAVREVGIEWAIRQGRELIAAGVPALHFY
TMGKADNVERIAKELFG
>A0A1I3YWB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sacchari|TrEMBL
MSRMKTVVERLRGTSPVFSVEFFPPRDAADEAVLWRSIRELEGFDPAYMSITYGAGGSSR
DGTIRNIARVATETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYG
EWVPHPEGLTYAEELVELVRSLGDFCVGVSAFPYGHPRSADLDTDTKYLVRKFKAGAEFG
IAQLFFEAEDFLRLRDRVAAAGCDALLIPGVMPLTTPRTLKTTIKLSGAACPQWLLDRLG
PLESDPKAFRAEGLDVVTELCERLIAEGVPDLHFYTFNRSKATREVVQRLGLVPVRA
>A0A0G3HFW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium uterequi|TrEMBL
MSFRSQAAPRWSASAPVDSGEPATHHDTVDRIALSFEIIPPRWGNETDVAALDHLLAELA
VYYPDYVCVTSSQRSGWLDGTAALIERITATTRMRPVAHLACTTGPAEELTRGVNRLIDA
GVRGILALRGDLPAGQDRLPAGYLPYATDLVRVIRAVEARQAARFAAGSLAVGVACYPLG
HAESPTPEQDFDVLLTKQRLGATFAITQLFFDAGDYLSFVRKARLAGVTIPLIPGIMPMT
SVARLERMGRLAGIAVPERLRRTLSEAAEISPAAEHEAGLRATVDLARACLAGGAGGLHL
YTHNDAELTHELLARIGVMPGVSHYDALAGVALPTAC
>A0A1U7M7A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierella creatinophila DSM 6911|TrEMBL
MKIRDLFNEKEFVYSFEIFPPRHDYPIETVYSTIEELSKLKPDYISVTYGAAGSIANNRT
AEIANLIKDKYGIESLAHLTCIGSDKQKIDNVLADLKEKKIDNILALRGDRPEDGSNIDR
FEFINSQDIIRYIKENSDFGIAAACYPEGHIESRDKNVDIEVLKRKEEFGTDYFISQLFL
DNNYFYDFLDKAEQKGIKAPIQAGIMPVINKRQIEKITSLCGATLPKKFIKIIDKYEHDK
DALRDAGIAYALEQIVDLISSGVRGVHLYTMNNPYIAKRINENMDCILSSVRKESKVASL
G
>A0A1Z8V4B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Puniceispirillum sp. TMED52|TrEMBL
MTDTIDMIAKAGANWSIEVTPPGAAKIEDFSSILAEGTTVNVTFLPGTNPVDTIDVAKRL
RDSGLVPVPHIAARSLKSKDQLAELVADMTSRANIDEVLVIGGGVTQPVGEFASSMEVLK
TGILQSAGIRKIGVSGHPEGSPDIKDNLLADALAWKNEYARKEGLDLYIETQFCFDADAV
IAWEKRIRADGNTLPIRIGIPGPATIKTLFRFAQISGIGPSMRFIAKQARNVTKLLTVQS
PHLLIAGLAEAMANDPDTKLNHFHYYPFGGVAKTAVWASQVASGQVKLLPKGGFQVIEQA
ASKAS
>H8X156|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida orthopsilosis (strain 90-125)|TrEMBL
MKITDKLNQAHVGIANPPPATFSFEFFVPKTAQGVQNLYDRMDRMYDLNPIFIDITWNAG
GRSSTLTNEMVYTAQSTLGLETCMHLTCTNMQVELIDEALDKAYKSGCQNILALRGDPPL
DGSESTGDFKYAKDLVRYIRKRYGDHFNIGVAAYPEGQPEEEDEVKTLHYLKEKCDEGAD
FIITQMFYDVDNFISWCEKLRKIGIEIPIIPGIMPISTYAAFIRRANWSQIKIPQHFLDA
LDPIKDDDYLVREKGTELVSDMCNKLIESGYVNHLHFYTMNLEKSTVMALEKLNLIEAVK
SHEVVGGTELPWRKSLHPERSKESIRPIFWQNRKYSYISRTATWDEFPNGRWGDSRSPAF
GDIDLCASELLRQSPKRALELWGVPQNLKQLSDLVVSYLSGELKSLPWSDGAVGEDTKVI
VDDLINLNKRGLLTMNSQPALNSVKSSEKVFGWGPKNGYVYQKQYLEFICHKDVVDKLLT
RIYDFNKSQGDASSSIISYYAVDLSGNLQTNCKPDDINAVTWGVFPGEEILQPTIVEQTS
FLAWKDEVYRLFSEWNKVLSSNLVDIDDESKLHNFTHLMNEVGHDFVLCNLVNNDFIDSN
STLFNLIYDLNLPELS
>A0A366AXH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio paracholerae|TrEMBL
MGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKTLQPKFVSVTYG
ANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQNIVALRGDI
PAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRAI
TQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPNWMVKQFEG
LEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A2M7H610|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG15_BIG_FIL_POST_REV_8_21_14_020_46_15|TrEMBL
MKAGTNLEKVLESGAFAVTAEAGPAKGAVTSVIERKGEMLKPCCDAVNVTDNQSAVVRMS
SWSSCVLLKRLGLDPVMQIVVRDRNRLAIQSDVLGAVAMGIQNILCLSGDHQAIGNHPDA
KGVYDIDSIQLIQMLKGMRDEKKFQCGEEISGEVPIFIGAAANPFAAPFEYRVLRLAKKV
KAGADFIQTQAIFDVAKFAKWMEMVRDRGLDKQTHILAGLVPIKSVGMARYMKDYVSGVY
VPDEVVTRLEGAKNAKEEGIKICLETIEQLKEIQGVHGIHIMAVAWEEMVPHIVEQAKLL
PRPVV
>A0A420W4D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium puteale|TrEMBL
MKITDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTEGGHAFATDLLEQVTDMNKGKYLHEDIITSEKTDFCIGVAGY
PEKHFESPNFNTDFKYLKQKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVASCKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLV
>A0A0U3RT20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii XBB1|TrEMBL
MSKKVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A5E8H881|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira yanagawae serovar Saopaulo str. Sao Paulo = ATCC 700523|TrEMBL
MASSVRPIFSNVIPHIRAIDFDINNCENLIHTLKSNQIPSVVVIKGDPPTDMSKRVYPTT
SIQMIKKLKKEIPQLKVFAAIDQYRVGIKNEFDYIELKKDAGADGFLTQPFFDMRLVDIF
SEKLNGLEVYIGISPVIAEKSQSYWESMNRAYFTKDFQPSMEWNVKFAKDVILYCSKNGM
NAYLMPIRINLAEYLHHIFT
>A0A1H3RZ14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Evansella caseinilytica|TrEMBL
MGLLEELQENIVVADGAMGTLLYSHGIGNCFEELNISKPEQVKKIHRAYIDVGAQVIQTN
TYGANYEKLSRYGLEDQVKAINTAAVRLAKTVVKEYKKAHEERREQLPYEHKYILGTIGG
IRTSPGKPILLSEVKRSFREQLHHLLAEGVDGLLLETYYDLEELETVLAIARKETGLPLI
AQLSLPEVALVQGGLTVKEAFAKLETSGADVVGLNCRMGPHHMIRSLETVPLPSRAYLSA
YPNASLPSYDNGRYHYSANDDYFQKAAIALREQGVRLIGGCCGTTPAHIKAVAEAVKGKQ
PLTEKKIARLPAQPALEITPPTAGKKTAVPLHEAVATRKTVIVELDPPKNLITSNYLLGA
KALKDAGVDAVTLADNSLATPRICNLSMSVLVKRQVDVPPIVHITCRDRNLIGLQSHLMG
LSALGLENILAITGDPAKVGDFPGATSVYDLSSFELIQLIKQCNEGISFTGKSLGRKTNF
TVAAAFNPNVRHLEKAVQRLEKKVAHGADYFLTQPVFSTGQMSEIYEHTKHIKAPIFLGI
MPLTGYQNAEFLHHEVPGIKLTDDIRRTMAACRDDKQQAKKQGIAIAKHLIDGALEYFNG
IYLITPFMRYDITVELTEYIRAKTGAATVSHS
>A0A2G6PFA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Contendobacter odensis|TrEMBL
MSTPSDGCRIFSCEFFPPISAEGMTRLQKTRQHLLSMHPAYFSVTYGAGGSTRNRTVEAV
LDIQANSGIPAAPHLTCIASIRDQIKELLEFYQAHGIRRIVALRGDMPSGMRDSGELRYA
NELVEFIRAEFGDYFHLEVAAYPEYHPQATTPEHDLDNFKRKVDAGADSAITQYFYNADA
YFRFIDNCNRLRISIPIVPGIMPITNYTQLARFSDACGAEIPRWVRKKLESFGDDRTAIR
AFGLDVVSELCQKLLDSGAPGLHFYTMNQSTATLAIIERLNLTIAMPTTNRGAEPRGC
>A0A353GDV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sumerlaeota bacterium|TrEMBL
MQIKDIYNQKKPVLSFEIFPPKPDYSLDTVFRTIESLKDLEPDFISVTYGAGGSNRARTI
EIAAKVKQDYQIESVAHLTCVGHSPAELDAIIDNIHNHGIENILALRGDPPRDQPHYAPQ
RGYYKESIELVKHIKSKGGFCIGAAAYPEGHTSAISWKQDWLELRDKVAEGVDFMLTQMF
FDNRLYYNFLENIRRIGITAPVSPGIMPVLNAKSIRRMISMSGASIPAKLLAMLEKYGDN
DADFEKAGIQYAIDQINDLVHNGVDGIHLCTMNKVEQTRMIVENSALSTGKAKS
>A0A4Q0P4J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leeuwenhoekiella aequorea|TrEMBL
MKITEHIKAANGKTLFSFELIPPRKGKSIQELYNNIDPLMEFKPPFIDVTTSREEYIYIE
KDGLLDKKVTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHFLGIHNV
MALRGDAMKEQQYFEATDGGHEYALGLVEQIAEMNKGRYLNNVVETSDCSNFCIGVAGYP
EKHLEAPSLKTDLKRLIQKVEAGADYVVTQMFFDNKKYFEFVDLVRAEGIDIPIIPGIKP
IAVKRHLQLLPQVFKIDLPQDLIDAVDDCKSNTEVRQVGIEWAIQQSKELMDGGAPVLHY
YSMGKSDNVHAIASALF
>A0A6B2JU79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoroseicyclus tamaricis|TrEMBL
MSLSHAARPGTRRATNGVLPMPRISFEFFPPKDIEGSFRLWRCVQTLAPLQPDYVSVTYG
AGGTTRQLTHEAVTAIHKTSGLPVAAHLTCVDASRAETMEIAESYAAAGVTDIVALRGDP
PKGTGAFRPHPEGFTSSVELIEALAATGKFRLRVGAYPEPHPEAGSTQDDVDHLKRKLDA
GADEAITQFFFEAETFLRFRDACAAAGIDKPVTPGILPVENWAGVRRFAAACGATIPDDI
ARAFENAEHAGASDLLATALATELCEALVDEGVDAFHFYTLNKPEMSRDVCHALGIAPRP
ALLQVA
>A0A0X1SW57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas agarici|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASHDPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKDDLRDLLAQYKAAGIHRIVALRGDLPSGMGMASGELRHANDL
VSFIRQETGSHFHIEVAAYPEMHPQARNFEDDIQHFVHKVNAGADSAITQYFFNADSYFY
FVDRVRAAGVNIPIVPGIMPITNYSKLARFSDACGAQIPRWIRKQLEAYGDDSQSIQTFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLRLPR
>A0A1S1PQ43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. RSm-3|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWETVSKLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGVSIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIHEFHLYTMNRAPLVSAVLDNLGFSRRAAKSAGAAA
>R0CQQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia pickettii OR214|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRGILNTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGEAFHIEVAAYPEYHPQSRSARHDLENFARKVKSGADSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A2G3DRX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobutyrivibrio ruminis|TrEMBL
MFREMLSRDASMSFEVFPPKKNDEFDNCYNVLDSLAKLKPDFISVTYGAGGSRSKKTVEI
ASYIQNTLKIDAMAHMTCVGSSEDDILEVTKDLEASGVSHVLALRGDKPRDMSDEQFAKR
IFPHATDLIRFLNTNTNLDVSAACYPEKHPEAMSIDSDLAFMKMKQDMGAKMFISQLFFD
NADFYRFVERADKAEIHVPIVAGIMPITSAKQIGSTVTLAGSSVPKKLADICAKYSDFPE
DMRKAGIEYAIDQIRDLRKCGMGHIHLYCMNKPKMTEIICKSI
>A0A4Q4B525|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium 144Ye|TrEMBL
MKVTEHIKQAKGKTLFSFEIIPPQKGSNIKELYNNIDPLMEFKPPFIDVTTSREQHVYIE
KDGLLDRKITRMRPGTVGICASLKYKYNVDTVPHVLCGGFSREETEYLLVDCHYLGIDNV
MALRGDAMSHQKYFEPSKGGHQYASELVEQIQNLNKGKYLHDVIEASDKADFCIGVAGYP
EKHIEAPSLQSDLKRLKHKVDCGADYVVTQMFFDNKKYFEFVEAAKQAGITVPIIPGIKP
IATKKHLQLLPQVFKIDLPEDLIDAVEDCKDNKAVRQVGVEWAIKQSKELQNAGVPVLHY
YSMGKSDNIKAIAERLF
>A0A249PBY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sojae CCBAU 05684|TrEMBL
MSPDINPRDPAAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPEDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLQTVRTMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCVDIINEVKEIDGVSGVHV
MAYRQEEYVAEIVHESGVLKGRRPWHREAAPTDALVAERLEHIREGIEENQQQMAEAAAH
HPH
>A0A0S8G095|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium SM23_32|TrEMBL
MSNLSEALARGEFLVTGEIGPPKGTNIEKCLEDAEHLRGKVTAINVTDIQSAVMRFGGLA
TCHMLVERDLEPVFQMVCRDRNRLALQSDLLSAHVLGIENVLCLTGDHNILGDHPDSKPV
FDLEAVGLLQCVQTLMEGRDMAGNELDGAPPFFPGAVVAPGSEPVEMQIIRMEKKIAAGA
KFFQTQAVYDVDQFADFMGRVEGFGVPVLCGLVLLKSVGMARFMNANVSGVNVPDRLIAR
LKADKEKTKSGEAAIEIAVETIEGVKDLCQGVHIMPLGWDHLVPDIIDRAGLA
>A0A1I7L6K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium arachidis|TrEMBL
MTDLTIPARNEGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPNFVSVTYGAG
GSTRERTHSTISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPVG
GIGTPYSSHPEGYQSSAELVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGISIPIVPGIMPMHNFKQARNFVTRAGTTVPDWF
AAKFEGLDDDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A369VIV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. BoFeN1|TrEMBL
MNAANTAPAALPVSFEFFPPKTPEGIEKLRTVRQQLYALQPQFCSVTYGAGGSTQDGTLQ
AVQSILDEGQQGASHFTCVGASRDSVREKLALFQSIGVRRLVALRGDLPSGYGSMGEFRY
AADLVAFIRAETGDRFHLEVAAYPEMHPQARSPEADLQAYAAKVKAGANSAITQFFFSTD
AYFRFVDEAHKLGADVPVVPGIMPIINASGLLRFADSCGAEVPRWIRLRLQGFGDDTASI
KAFGLDVVTSLCEQLRQRGVPSLHFYTMNQSATTLEICRRLGL
>A0A402AAE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tengunoibacter tsumagoiensis|TrEMBL
MVRTTSPFLERLAAGPLLCDGAMGTELYARGISYDRCFEQLNLTNPELIKSIHLEYISAG
AQIIETNTFGANRYRLIEHGLEHTVSKINRAGAKIAREVRDLSETPIFLAGNIGPLGHPL
SPLGGISAQEAREAFLEQAEALLQTGVDLFLLETFSDLTEMQEALSVIRNLTDLPIVALM
TFGEDGTVASGEDAQLVAQQLRASGADVVGANCALGPASMFDVVVTMSGSQIEPLTIAVQ
PNAGLPKRVGNRFMYGATPDYFAASAQRFLESGVRLIGGCCGTTAQHIAAMKKVLVEYAP
ELPHQEATMIEHVRERVRVRETSDETAAHLPPTQLARLLQQRKFVISVEMSPPRSVKFTR
FLQNARTIQESGADFINITDNAMARVRMNNIAAARLIQQHIGIETIVHFTPRDRNLMALQ
SDVIGAHATDIRNMLIITGDPPMHGDFPNATGIWDVDSIGLIAILNKLNQGLDARGRKLA
VKSAFCIGCAANPTATDIEIDIERLQQKIEQGAQYIMTQPVFDTDTLLAYIERYNQRYGK
LPIPLLAGIQPLHSYQQAEKFHQEVPGLVIPDGIRTRLREAGEAGSQLGIALAREMIDAI
APLVQGVYLMPIDRFELASELVAYIRERVLMQQSAQDGEPDRIEIDAAQ
>A0A7C4BZ53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacteraceae bacterium|TrEMBL
TTLAHLTCVNHTREQVGALLDRIQRLGCRNILALRGDPPDGGRFQPTAGGFRYAAELVAF
TRQRAGEFSIGVAGFPEGHIACAEGKLADWNHLKNKIDAGADFVITQLFFDNTDFLALRD
FLVKAGVRVPVVPGMIAILSASQIKRFTQLCGARLPQPLAARLEQLEQDDAAAAEFGIEY
ASRQCEQLLREGVPGFHFYTLNKARSTLQVLNNIGLA
>A0A7X7RED7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKITDVFKQKERTFSFEFYPPKDEIAAVDLGINIGQLIKLDPSFVSVTYGAGGSTRSRTF
ELVDYLKNRIGLNTVAHYTCVGSTKTKALEDLKNLRNRGLQNFMLLRGDPEIGSKYGFIP
CYDGFANATELISFARENFEDCCIGGGAYPEVHPESVNAEVDIRNLKKKVDAGCDFLITQ
FFFDNQKYFDFVTSARTAGIQCRIIPGIIPLTKYSQLERFVLLSRAGIPPDFKEQLERNR
YNPQAVYQAGMDFAINQCRDLLHRGAPGIHFYTLNKSRATVEIYSTLKVK
>A0A7X8GA02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKLTDIFNIAEKTFSFEFFPPRDQIAALDLGINIGHLLRLRPAFVSVTYGAGGSTQSRTF
ELVDYLKNKVGLNTVAHYTCVGSDRKKTLEDLQALRRMGLQNFMLLRGDPKAGSEQGYVP
LKDGFANATELIAFARKHIKNCCIGGGAYPEVHPESLNAETDLQHLKMKVDAGCDFLITQ
FFFDNRRYFDFVARARKEGILCRIIPGVIPLTKYDQLERFVKLSRAAVPPAFLDQLESNK
DNPDAIYNIGMDFAIRQCRDLLMLGAPGIHFYTLNKSRATVEIYQTLMVR
>A0A087N4G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. BF-4|TrEMBL
MGLLEKLQTSIVVGDGAMGTMLYATGLASCHEELNLLQPALVEKIHNEYIAAGADVIQTN
TYGANAIKLARYGLADKVTEINKAATHLAKKAADGNVYVLGTIGGIRDIRKTDVTLTEIL
QGVKAQATVFLTEGVDGLLLETYYDFDELVATLELLREMTTLPIIAQVSMHEVGVLQNGK
PLNEALTELERCGADVVGVNCRLGPFHTIQAFEQVDLPQHAFLSTYPNASLLDVEDGRIV
YESEYDYFGRAAATLCKQGVRLIGGCCGTTPKHIAAVKKHVASLTPINEKPKRQIAVDFV
REAEPRTVKPLHEKAKQERSIIVELDTPRHLEVEGFIKGSEQLYAAGADVVMMADNSLAS
PRISNIAMGAMIKEKGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKVGD
FPGATSVYDVTSFELIALIKQLNEGISFSGKPLRKKANFSVAAAFNPNVRVVARAVPRLE
KKIEHGADYFISQPVYTKEKIIETYEATKHLSVPIYIGIMPVTSYRSAEFLHHEVPGIKL
SDEVLTRMRDCGEDKERATQEGIAIAKELLDTAAKYFKGIYLITPFLRYDMTLQLIAHIK
EMDEAAKGVSING
>A0A355B6D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinae bacterium|TrEMBL
MSDIVDEIRSSGTSVSIELFPPKTEAAAARLVEEVGRIQEGMRVAFTSVTYGAGGSTREG
TLNLVLDLAKRYPGRVVAHLTCVGADEESLSSLLAVYLKSGMGDIMALRGDIPEGMTREE
AAAGGFRYAVDLVRWLRELGGVSSIGVAGYPEGHPETPDRARDLEHFLAKAEAGADYAAT
QFFFENADYFDFIEETARRGLGIPVAPGILPVRDIDQVVRFAAMCGASVPERVIAALEPY
REDPKGFREKSADLSAEQIGELIEAGVRHIHIYSLNKSDIVLRVADRLGWRF
>A0A0P9TD73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. photiniae|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAESSLAVWNNLQLPR
>A4ATQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter sp. (strain HTCC2170 / KCCM 42371)|TrEMBL
MKITDHILNAKGKTLFSFEIVPPVKGKNIQELYNNIDPLMEFKPPFIDVTTSREEYVYIN
KSGLLDKKLTRRRPGTVGICASIQHKYKVDTVPHILCGGFTKEETEYVLVDCHYLGIQNV
MALRGDARSEQKYFEATKGGHAFASELVGQIQNLNCGKYLHEEIESDNCADFCIGVAGYP
EKHLEAPSLQSDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVDAAKEIGINVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVDDCKDNKAVRQVGVDWAIQQSKELKAAGVPVLHY
YSMGKSDNIHAIAKGVF
>A0A1Z8QJ48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium TMED41|TrEMBL
MELSVEFFPPKTEEGFLRLSRAAEKLSSLPVEYASVTYGAGGSTREGTQSAVKILGGIFK
NAVPHISCIGSDKTTINNILKTYINSGLNHLIVLRGDLPSGFGKGGEFSNAVDLVKYIRE
QFKENFRIEV
>A0A450U545|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. LFY|TrEMBL
MNLSGSNTRVFSFEFFPPKTPKGHDKLRTTWQRLSRLNPDFFSVTFGAGGSTQSGTMETV
LEIQKHAGIDAAPHLSCIGSTRVKIRKILDHYLSHGIKRIVALRGDFPPDMVRLGEFRYA
NELVEFIRAETGTDIHIEVAAYPEFHPTAPSASVDLENFKRKVDAGANSAITQYFYNKDA
YLRFVDNCERIGVHIPIVPGIMPITNYVSLAGFSQRCGAEIPRWLDWRLQEFGDDMSALQ
SFGIDVVTELCRQLLEAGAPGLHFYVLNRVQPVMTIWENLDLPKIRDSA
>A0A1V2V4B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter genomosp. 33YU|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLNLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLESAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A139CRG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Frackibacter sp. T328-2|TrEMBL
MGQNKLKESILNKDEFTVTWELVPGRGAREANQEFIFEGAEQAAESDKVDGITITDNPGG
NPAISAEYLGMKAEEIGIPALVHFTCKDKNRNQMESFLYSLEREEVNNILVMTGDYPVGG
YDSRSRPVYDMDPTQVLEMVTDLNDGLKYKDAFGRSVELQETNFFPGAAVSPFKQLESEQ
MVQYYKLKKKIEAGAKFIIPQLGYDARKFHELIQFIEMNDWDIPVIGNVYVLSYGASRAM
NANRIPGCVVTDKLVDKLAEEKEADDKGKHARLMRAAKMYAYMKGMGYAGVHLGGHGMGI
EDVEFIVDKGEELAPNWQDYIHEFEFPMEDGFYYFEKDEETGLNTKQPAARTHKPSKGLM
NRTFRVMHHALFEPDSPFFKPMQYLCKSVDDSSLEKPFEFMERVIKTVSNDCQECGDCAL
FDLAYICPMSQCPKNQRNGACGGSRDGYCEVYPNEKKCLYVRVYDRLKAYGEEKQLQEYQ
IPPVNWDFHHTASWLNFFMGRDHSAKRLGITPPGSESEGKSKKA
>A0A6L3BHC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. TE8-1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMQYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1I1M7J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. OV322|TrEMBL
MDFRSELKKRVLIGEGAMGTLLYSHGIDHCYEELNSTDPGKIETIHRAYLEAGADILQSN
TYGANYHKLKRYGLEDEVSAINRNGVAIARKASEGKAFVFGTIGALRSIRKNDLSMEEIK
RSFREQLYSILMEGPDGLILETFYDLEELETVLPIARKETDLPIISNVTLHEIGYMQNGI
HLNEAFQRMEQLGADVAGINCRLGPHHMIRSLEEVPLMKNTPISVYPNASLPEYIDGRLI
YEAVPEYFGSSALKLREQGAAVIGGCCGTTPLHIAEVKKKLGTIPPVTQKEIKARKIEII
EIIDDKTPALHQLAKRKRTVLVELDPPKKLGIEPFMMGAKALLDAGADSVTLADNSLATP
RISNAALGVMLKNQMGANPLIHLTCRDRNLIGLQSHLMGLQTLGLNELLVVTGDPSKIGD
FPGATSVYDLSSFDLISLVKQFNEGLSFSGQSLGQQSHFKIAAAFNPNVKYLDKAVQRME
KKIICGAQSFLTQPIYSVNQMEEVYEATKHLDTPVFAGIMPLTSARNAEFIHNEIPGITL
PDDVRRAMAAAGSNPLLARNEGIAIAKALADAAMEKFQGIYLITPFMRYEMTVVLTEYIM
KTDSKKLAGVTAYE
>A0A2K1EJ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. F4|TrEMBL
MKPDLRTVLNREIIVGDGAMGTFLYQLGFPVNTSFEELNITSPDVISDVHGQYLSAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
LELARNYEQQIDALLSEGVDGILCETFYSLDEIRIALHSVRKYSDIPVICQFAVDQVGRT
QDGFLVAEAFSVLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAKSFVDLGTRLLGGCCGTTPDHIAAISKALNRLQPPPLASKEALS
KESFQVAEQIADEEERGNGRHISEPNIVDLVKERHTVIVELDPPRDLDITRFMQGAHALK
KAGADALTLADNSLAVTRMSNMALGHLVSIETGLRPLIHIACRDRNLIGTQSHMMGFDAL
GIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGVAFSGKPLKQKANFVVGA
AFNPNVKHLGKAVQRLEKKIASGADYVMTQPVYDHELIAAIAEATRHLEVPIFIGIMPLA
SGRNAEYLHNEVPGIQLSDEVRARMSGLEGPEGRAMGVSIAKELLDTAMEHFNGIYFMTP
FMFYEMTAELTSYVWQKSGRAQAPLFRL
>A0A7V4ANA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus tengchongensis|TrEMBL
MKIRDLLKARKGPLFSFEFFPPRTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRERS
VLWAKRILDLKLNALAHLTVAGQSREEVAEVLDRFVEAGVENILALRGDPPQGERVFRPH
PEGFRYASELVAYIRARYGEELSVGGAVYP
>A0A1I2ZVQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfallas arcticus DSM 17038|TrEMBL
QTQCIFDMERFERFMEMVRERGIDQRVHILAGVTPMKSWRAAKYIQNNVSGMIVPDDLVE
RLKNAEDPKREGVEICIEQIKYIKENIKGVHGVHVMAIAWEEVVPEIVERSGLYPRPQK
>A0A1Q4DMG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium 64-17|TrEMBL
MSAFTLEATRPTADELVRLAALVPPGQPLYLSHVPSQGLREMADLAMAVQRAGLDPVLHL
AARRIASADDLTECLKRACGEGGMRRVLVIGGDIPKPLGPYADALALIRAMDWRALGIEE
IGIAGHPQGHPAIAADMMTRALTDKLAAARDAGLHAHIVTQFVFSAAPIMTYVRDLRAAG
VTAPVRIGLAGPTKLTALLRYAARCGVAASAQGLMSGAATALAFGGRVGPDAILDALRVA
APALGNIAPHYFSFGGLIETARYASVVAPIVPGRAITPPEQEFADPTLPNQEPVS
>A0A1F9Q4V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula sp. RIFOXYB2_FULL_45_6|TrEMBL
MSELNTHSRLEKILKAGHLGVTSECGPPRGSDAEEVKKKGLMIKDYVDAINVTDNQTAMT
RMSSLAACIHLKLLGIEPVLQMVTRDRNRVALQSDILGAASFDIPNMLCLSGDHQSFGDC
KSGQNVHDLDSMQLVQTVRYMRDEGKFLGGDAIKRPPKIFVGAAANPFADPFEIRVPRLA
KKIACGAEFIQTQCIYNIDKFKEWMRQAVERGLHEKTFIMAGMTPMKSVGMAKYMKNRVP
GMDVPDEIIARLAGVPKDKQAEEGINICVEHIRELKEVKGVAGFHIMAIEWEEKVPEIIK
RAGLYPRPQV
>A0A2E2PFY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudooceanicola sp|TrEMBL
MTAPVVSFEFFPPQNLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNATREETLGIARSFAEAGVSELVALRGDPPKGTGAFQPHPDGFANSV
ELIAALKQAGEFTIRVGAYPDTHPDAASTAADIDWLKAKLDAGADEALTQFFFEAESFLR
FRDACAKAGIDKPITPGILPIENWKGASKFAKACGTYIPDWVDDAFTTAARDGREDLLAT
AICTELCSDLIDEGVDKLHFYTLNRPELTRDVCHALGVTPKLNLQNVA
>R7R3H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:100|TrEMBL
MKISELLNQEKATLSFEVFPPKKDTDFENVERAASDIAALHPSYMSVTYGAGGSTKGHTI
QLAQSIQKQYQVPTIAHLTCVCADHKSIKTALDEMKNAGIENILALRGDIPQNYEGQVFT
DFAHASELAALIKEYGDFCVGGACYPEVHPDSSSRKEDILGLKRKVEAGCEYLTTQMFFD
NNIFFNFMYRVREAGITIPIIPGIMPITKKVQVKNAVKLSGCNVPERFKNIVDRFGDSEE
AMKQAGIAYATDQIIDLMANGVRHIHVYSMNKPEIAAGIQKNLSEILKA
>A0A8B2XQ74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. AM17-18|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1Q9P6C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain AB_25)|TrEMBL
MLNKGEFVVTAEIGAPHGADSNLIVERTEMVRDYCDAINVPDNARGVPTMSSTTCAHYVL
QSGAEPIMHLTTRDRNRISLQSELYGAYALGIRNVLFVAGDHARYGSHPDAKVVYDLDTI
NALALTTKLREGTDFAGDELEGVPEFYIGATFNPNDSCLEDHVLQTEKKQKAGAQFFQTQ
AIFDSEKLKDFMGLASGLNLKVLAGIIPLRDVEMAEFMNTQIPEITIPEGIIKRMDYAGK
GLDEGARIEEMQREGLRIALETIERVRRIKGINGVHLMGVGWTESIVELAKGASLFPRPE
>A0A7C2CM99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
MKIEEWLALFQERVVLADGAMGTMLYNKGIYLNLCFDEVNLTNPDLVRSIHREYIQAGAE
IIETNTFGANRFKLKKYGLEDRVKEINKAGAIVAREEAGSRVWVAGSIGPLGVKIEPWGP
TSVEEAEEAFREQVRALLEGGVDLFILETFSDINEIHQAIKAVQKEAPNFLIVAQMTIEE
DGNSLYGTSPEVFTRKLEEWGAHIIGVNCSVGPAAMLQCLERMAKVTSRPLSAMPNAGVP
RNVEGRNIYLCSPDYLAEYSRRFILTGARLVGGCCGTTPAHIRAIRGAIRSMQPARRQAV
FIREEVEEAVEIVPKPMREKSALGKKLSEKQFVVSVEIVPPRGCDPSGAIEIARELKARG
VDCVNIPDGPRASARMSSMALALLIQAQTGMEVILHYTCRDRNLLGIQSDLLGIHALGLR
NLLLITGDPPKLGDYPDATAVFDVDSIGLTNVVSFLNRGLDIGRRRLQVPTSFLIGVGVN
PGAINIDYELSRFRWKVEAGAEFAITQPVFDVNLLEKFLQRIESYRLPIIAGIWPLASLR
NAEFMHNEVPGARVPDEIMERMRRAQEVSPERAREEGVAIAQEITVRIKDMVQGIQISPP
SGRYDLALKVLEVL
>A0A0A8JFS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. (strain OxB-1)|TrEMBL
MSLLDKLKTDVLTADGAIGTLLYSYGIDFCYEELNVEKPEIIEKIHQDYIQAGADVIQTN
TYSANALKLARYGMEDRVKEFNEAAIQIAKKAAAPGGQFVLGTIGGIRGIRKSDATLQEI
QSIVQQQAQHLLTGDPDGILLETYYDFEELSAVVQLIRTMTDTPIIAQVSMDEPGVLQNG
LSLNEALHRLEALGADVVGVNCRLGPFHTNQAFEEVTLPEKAFLSAYPNASLLDVEDGRI
VYVSEADYFGRAALSLRNEGVRLIGGCCGTTPKHIEAAKKQLAGLAPVVAKEVKQQKPVV
IREAKPAVNEPIHEKVKRERSVIVELDTPRTLEIEKFVEGANLLNEAGIDAITMADNSLA
SPRISNVAMGAILKQQYNIRPLIHITCRDRNLIGLQSHLMGLDALDIQDILAVTGDPTKV
GDFPGATNVYDVNSMELTQLIKQLNEGISFSGKPLKKKASFSVAAAFNPNVRVVERAVKR
LEKKIESGADYFISQPVYSKEKIEEIYEATKHLDTPIFIGIMPLTNIRNAEFLHNEVPGI
KLSDEVLERMRACGDDRQKSTEEGIQIAKELVDTAARLFNGIYIITPFLRYDMSLELIQH
IKELDAKKERELVHANSSN
>A0A329EQE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Priestia endophytica|TrEMBL
MGLLEDLQSKVLIGDGAMGTLLHAHGIDNCFEELNITKPEDIFNIHKAYQKAGASVIQTN
TYGANFPKLKRYGAEEKVKDINIEGVRLAKKAVGDSGYVLGTIGGIRSFQKSIISLEEIK
RSFREQLFWLLSEDVDGLLFETFYDLEELKTVLEIARRETDKPIVTNVSLHEKGVLQDGT
PIVKALKILEELGADVVGTNCRQGPYHMLEILEEVPLLDKSFLSAYPNASLPQYVDGRLI
YETDPDYFYKTALAFKDQGVRLLGGCCGTTPSHIEAMAKALTNAVPITEKTVKEAPPIEV
LSQEIQTQPHLHEIVQENHSIIVELDPPKKLGVDKFLKGAHALQAAGIDALTLADNSLAS
PRISNLAMASLLKDQLKTRPLIHLTCRDRNLIGLQSHLMGMHTLGFNQILALTGDPSKIG
DFPGATSVYDLSSFDLIRLIKQFNEGVSFSGKPLGQKTNFSIAGAFNPNVRHLDRAVQRL
EKKVDCGADYFISQPIYSIEQLEDVYKATKSLKAPIYIGIMPLTGAKNARFLHHEVPGIK
LSENILTRMERIEHDKEQSAKEGILLAKELIDRAYELFNGLYLITPFMRYEMTVELANYI
KAKELVSIERKI
>A0A853L3T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira tepidiphila MCCC 1A03514|TrEMBL
MMTVPEINAVRKHLKVSFEFFPPKTEKMEETMWRSIHRLAPLNPSFVSVTYGAGGTTRDR
THGSVTRIQGETGIPAAAHLTCVGHTKEEIDQIARSYWNEGIRSIVALRGDLPDAGDKYE
PTPGGYAYAVDLVAGLKEIADFDISVSAYPETHPDAPSSDFEIDYLKRKIDAGANRAITQ
FFFDNETYLRFRDKCVAAGIEAPIVPGILPVTNFASLLKFADMCGASVPQRLHWRFEGLD
EDPDTRRMVAFHEAISQVEGLISEGVTDFHFYTLNRAELTYAICHALGIRGTEQVAA
>Q49UL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)|TrEMBL
MSQLLDKLKHNILVADGAIGTILYSEGLDTCPEAYNITHPDKVARIHRSYIDAGADIIQT
NTYGANFEKLKPFGLEHKVKDIHYAAVEIAKQAANDDTFILGTVGGFRGIKQEDLELSSI
QYHTEIQIETLIDAGVDGILFETYYDLEELTTIIKATKRKYDIPIIAQITALNTNYLRNG
TEINTALQQVVKSGADIVGLNCHHGPHHMQQSFSHIELPDGAYLSCYPNASLLDIENSQF
KYSDNAAYFGKVAEQLINEGVRLIGGCCGTTPEHIQYIKSSVSDLKPVNQKNVIPIAKYT
GHSEKPTQKQNLTSKVKHRPTIIVELDTPKHLDTDLFFRNIKKLDDAKIDAVTLADNSLA
TVRISNVAAASIIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKTQTNFNIAGAFDPNVRKLDGAVRR
LEKKLESGTHYFITQPVYSKEKIKEVYEATKHLDVPLFIGIMPVTSYNNALFLHNEVPGI
KLSEDILEQFEAVKDDKAKTKSLSIELSKALIDTVHEYFNGLYLITPFQKVDYTLELANY
SKSITSTKQEAIL
>A0A7S6W4Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. YH12138|TrEMBL
MSLFSQYLLQRQFCISFEYLTTQKPHCVPTTFAGFPVCMTLADRVQSDTDIAPLEAMQDY
PQSIEKILHYSGKGRDISDFQTFLKDAQQHGVENLLLLSGDKLKQHHDGANDPSLRSRYL
ESVNQVMAAKNFGGFYLGVAFNPFKYAEAEKDAQYFKLNKKIQAGADYVITQLGFDMDVL
ISYQRYMQQYYPRIPVLACVMPLTFARARFMAKQKVAGIVLSADVLNFLQQEQQTDVIQA
EQNVYDRCALQILMCQQLGYAGVHLSACHKPEEQEKLQKAILQFATLTFEQCLAKWKMLW
RSSVEVNFQPTGANNHKAPVEQVLKYKSMHVMHELFFSSKLAKGAGSYIFSAKLWQKPKA
DAALLKTEFISKHGIVGCESCGQCRLAETLYICPETCPKGLANGPCGGSNLDRCEFEDRE
CIHSVKARLAKAVGQEKMLKQELIPTVAIETRHSSSWKNWFVPPSSSPAEQ
>A0A7Z1AGZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thiodiazotropha endolucinida|TrEMBL
MHTEHQQRNFSFELFPPKTEKGLENLKQNVAELNTKQPAYFSVTYGAGGSTRQRTFDTVE
WLMDEQITTAPHLSCIGANRDEILEILEHYKSIGIRRLVALRGDLPSGTGLGELGDLNHA
NQLVELIQETYPRLFHIEVAAYPEFHPQASSPEQDLIYFKRKIEAGADSAITQYFYNADA
YFRFLDNCQKLQIDIPIVPGIMPITNFTQLARFSDACGTEIPRWLRKRLEGFGDDLEAIR
SYGTETVIRLCERLLEGGAPGLHFYTMNQAKPTLAIWQALSL
>A0A4Q8WZ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTS
>A0A4P6RSG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria indica|TrEMBL
MPAPLAASEPAPVTGPPTGTSWLVRRPRRSTLVSFEVFPPRPTGDPDTVWRNIDAMAQAG
PDFFSVTHGHAGHHGVSREALRHLRRTTKTPVMAHFTCGGTDRAGLERAVDQLLDDGVRD
LLALRGDPPLGTGEWRTPAGGLGRASQLVELIRDVERRRFGTGFRPGQRPLSVSVACYPS
PARGRDFEADLASLWDKQEAGADYAITQVLYEPEDYATFLERARSEGIHIPVVAGLMPLS
NPQRLQRMTEITGVRVPERLTRFLRADTPEELRHRGVAATLSLIDDLMDLGCAGFHLYTF
NRPEAALTILEHLRVRDAAREYRGRSPAA
>A0A1S8XPV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. Rc5|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTAQGERLLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVR
GDPPGDPGGEWVRHPEGVLYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCATPILAGVMPVTQLSTIERSVQLSGAPF
PPALAARFAEVADDPEAVRRLGIEQAAEMCRRLLDEGVPGIHFITLNRSTATREVWQQLQ
VGARV
>A0A4R8M3B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminivibrio pyruvatiphilus|TrEMBL
MFIRDILGRTRPAVSFEIFPPKPETPLETIFDTIAALRKLSPDFISVTYGAGGSSRERTG
EIASAVQNRWGLTSLAHLTCMGSAPSEIEGVMEKLEQEGVSNILALRGDPRPGEERADSP
FRYAADLIRHVRKGHFRDFSIGAAAYPEGHPECASPEEDLRHLREKTDAGADFLITQLFF
DNETFFRFMENVRAAGIAVPVLAGIMPVLNTRQIGRIVSLCGASIPPKFARIMSRYEHSP
TALAEAGIAYATEQIIDLLSWGAEGIHLYTMNRPDVAERIMGSLSSVRDTLTGN
>A0A5E9WU70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. US25a|TrEMBL
MCNFSFEVFPPRMDENIKNLHAILDDLGQLSPNFISVTFGAGGSVNSQNTLEIASLIQKE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYNNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELRA
>A0A2V3ZPR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter vulgaris|TrEMBL
METQKQFKRRFSFEFFPPKTDMGWEKLQGVRNTLAEVDPDFFSVTFGAGGSTRDRTVQTV
LDLHKRGVSTAPHLSCVGATRDSIAELLDVYRDNGINRIVALRGDMPSGMGAAGELRYAN
ELVTFIRKHSGDTFNIEVAAYPEFHPQARTAEEDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTGMCEKLLAAGAPGLHFYTLNQAEPSVSIWKNLGLGEREKIAF
>A0A6G9PT03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinivibrio costicola|TrEMBL
MSYTHAGHIDALNQNIADLNGDINVSFEFFPPSTPTMEETLWNSVHRLKALKPKFMSVTY
GANSGERDRTHDIVKSIHEQTGIAAAPHLTCIDASEDELRHIARDYWQNGIRDIVALRGD
LPSPEKKPDMYAVDLVRLLKEEHDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQASRFAKMTNVRVPQWMHKQYQ
GLEDDPVTRQMVGASIAIDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGVRPLAAVS
>A0A7X1Z710|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus hircilactis|TrEMBL
MTKNESAARLSFEVFPPNTDVGTSKLLTTLDELKSLSPSFISVTCSNKRENIENTTIKVA
DYVTNVLNIPTVAHLPACALNQKQVENILKRCAELNINRVLALRGDLTPDLSTPSDFKYA
SDLIEFIQSTAPDFKISGACYPECHPESQSVISDLHYLKQKMDAGCQEFISQFFLDNECF
YQFQERCALSDINIPILAGIMPIINRKQALRLLKTSHTHLPRKFVAMLDKYEHNPIALRD
AGLAYAIDQIVDLLTQGVSGIHLYTMNNSQTAKAIHAATASLFEEACSTH
>A0A497HA80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MNHISNLHRVLSEKHFAVTAEIGPPKGSDKNIIIHKGEMLKGYADAYNITDNQTAVVRMS
SLAGSTLLLKLGLDPIMQLTCRDRNRIALQSDILGASAIGIRNILLLTGDHQSMGNHPQT
MGVYDIDSIQLIQIARNMRDEGIFQNGEEILRGKPDIFIGAVANPFSTPLEARIIRLEKK
IEAGADFIQTQSVFNLNRFQEWVDTIRSLGLDKKVHILAGVTPLKSIKMMQRMRFHVPGV
DIPDEIANRIENARDPKEEGYNIAIEILEELKKINGIHGVHITALFWEDIIPKLVKEVNL
YPRP
>A0A849ESH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatitalea sp|TrEMBL
MRVTRLYESKAPVISMEFFPPRDEKGAAAFDRTVDALMEPRPDYMTVTFGAGGSTREGSY
QTVKQLITDKRQPTVAYIAGYGLGPDDITQVLDRYQALGVETIFVVRGDKPREEGFTPHP
ESFSYASEMIAFIKRRYDFTLGCAGYPEGHPEAPSRKTDIDSLKAKVDNGAAYIVAQYFY
DNAFFFDYVDRCRSVGITVPIIPGIMPVYTLKMTQMLAKVCGATITSALQAQLEAVDPAD
KEAVLNLGIDFAAEQCKRLL
>A0A849EQU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatitalea sp|TrEMBL
MSDNGYKSGSNLEKVLKAGHFAFTGECGPPKGANVAHLNEKMAPLRGMVDAVNVTDNQTA
VVRMSSKAASALMVQAGIEPNFQMVCRDRNRIAMQSDILGAHALGIRNMLCLSGDHQQFG
NHPESKNVYDIDSMQLIALVKKMRDEGKFLNEEEIDEPPRMFIGAASNPFGDPTEFRVYR
LANKIDAGADFIQTQCIYNMPRFREFMKRAVAMGLTEKCYILAGVTPMKSAGMAKYMSKF
VPGMDVPPELIKRIEGAGKGKMAEEGIKFAIEQIEEFKQMPGVAGVHLMAIEWEHKVPEI
AERAGVLPRPRVD
>A0A844YYF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteraurantiacibacter buctensis|TrEMBL
MSYEKIHPRWELPRLNMVDGYSLEMTAKEIEGLREAAHLIRPATQVAVTFLPGETLEQRI
EAAVLVRELGFEPIVHLSARRIESQEQLDWYLGEITSKAQVKRVFIIAGDPPEPEGPYSD
SLQIIETGLLEKHGIEIVGVGGHPEGHPNNTPAELWVWMEKKLAAIRAHGMVPLVLTQFA
FDDDAIVNWLAEMRQRGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGISLTN
LIGSAGPDKLVNSLDKKLGAEHGRVRLHLYPFGALTASAEWINEYHAKHS
>A0A436E1B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.004.05.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVA
>A0A4U0Q8Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus oryzae|TrEMBL
MTFDAVRGRSSEGWVTQTPSIVDRIGSSGGRIPFSVEFSPPRDADAEARLWRAVREFEQM
QPAFVSMTYGAGGSTRDRTVRVTGALAEETTLLPVAHLTAVGHSVDELRAMVGAYADRGI
SNILVLRGDPPGDPLGEWVRHPEGVEYAEELVRLVRDLGDFHVGVASFPEGHFRAPDLDH
DTRYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVSRCDAEQGAKPIIPEIMPITSLRSVK
RMVELSGSQLPRELADRLDRAAGHGPEENRAAVREIGIELATEMSERLIAEGAPCLHFIT
LNFARATREVLARLGLASSVR
>A0A0W1EVK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. HIX|TrEMBL
MTTPLPSQSEARRAAASPLFAGLAGDIGISFEFFPPKTEKMGETLWESIRTLEPLGPNFV
SVTYGAGGSTRERTHATVARIVQETSIPAAAHLTCVDASRDEIAEVAQAYWDAGVRHIVA
LRGDPPVQGETFQARPDGYSCAAELVSGLLEIAPFEISVAANPETHPEALSAAADIDNLK
RKLDAGATRAVSQFFFEPDTFFRFRDAAAAAGISAPILPGIMPVSNFGAITRMSAMCGTD
VPRWLAQLFDGLDDLPAARQLVAATTAAELCRRLYAGGVRDFHFYTLNRAELSYAICHML
GVRPAAPATEKAA
>Q3BXE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. vesicatoria (strain 85-10)|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGAAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCQRLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>N1W9L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira vanthielii serovar Holland str. Waz Holland = ATCC 700522|TrEMBL
MHISQVLGKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEQTGLTIISHLTCVGSTKDEIRDILKRYEKSGIHNIMALRGDPPKGQTEFQKT
ENGFAFAGELVGFIKKEFPQMGIGVAGFPEGHPSTPNRLKEIEFLKWKVDQGADYICTQM
FFNNNYFYDLVERCEIAGIKVPIIAGIMPVTSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDVYAENVGIHWATEQVRDLLDHKVAGIHMYTLNKSKATRKIYESLGIRNFDSIG
>A0A646KFF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces jumonjinensis|TrEMBL
MALGTPSTRTDRARTVRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVRATEQIAADTTLTPVAHLTAVDHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVKHPDGVTYAAELVRLIKESGDFCVGVAAFPEMHPRSQDWDTDIQHFVD
KCRAGADYAITQMFFLPEDYLRLRDRVEAAGCDTPIIPEIMPVTSVKQLERFAQLSNAAV
PRRLKDRILDVKDDPVAVRSLGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYENLG
LHQQS
>A0A258UEF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilales bacterium 16-45-7|TrEMBL
RQETGDWFHIEVAAYPEFHPESPSAAKDIINFKRKVDAGANSAITQYFYNADAYYRFIET
CEHEGIHVPIVPGVMPIYNYTQLARFSGVCGAEIPRWLRLRLEAYGDDLASLRAYGADVV
TEMCSRLIDSGVKSMHFYTLNQAGTISKIIQNLHQ
>A0A4Z0Y8L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylaria hypoxylon|TrEMBL
MHINDMVADAERTGQPSFSFEYFPPKTAQGVQNLYDRMERMSDFGPKFVDITWGAGGRIA
ELTCDMVLQAQTFFGLETCMHLTCTDMGEEKVNDALQKAYKAGCTNILALRGDPPREKEK
WEATDGGFQYARDLVAHIRKKYGKHFDIGVAGYPEGCDDNKDEESMLDHLKEKVDMGGTF
IVTQMFYDADNFVRWVGKVRERGITIPIIPGIMPIATYASFVRRAHHMNCKIPEKWMAAL
EPIKNDDSAVREVGKVLVAELCRQIMSAGIVHMHFYTMNLAQATRMVLEELDWLPSSQRP
RQQPLPWKQSLGFGRREEDVRPIFWRNRNKSYISRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGSNESNRKKWGEPASISDIASLFTRYLEKDLDSLPWSEAPLSGEAVSIKDDLIN
LNKRGFITINSQPAVDGVKSTHPIYGWGPPNGFVYQKAYLELFVHPDLYGEVIGRIEGRE
ALSYYAVNQAGNFTTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAYRLGNDW
ARCHEANSPSRALIEGIMNQWYLINIVNNDFHDTKAVFELFDGLEVKDLGTPVSSAPHTN
GTNGTHKETNGIAASN
>A0A410DBQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporolactobacillus terrae|TrEMBL
MGHSILDVLKERILIGDGAMGTLLYSYGIDRCFEELNVSQSEAVRHVHEAYINAGADVIQ
TNSYGANRIKLARYGLEHEVARFNRASVQLAKQAAKPETFVLGTIGGIRGFQKQSVELDT
IRASFREQADALLSEGIDALLLETYYDFDELRDVLQIARTMTDLPIITHVSMQEPGVLQN
GMPVAKALEGLEAQGADVVGTNCRLGPFHMIEALRGIPLPKKAFLSAYPNSSLPDYRDGK
LHYENEPEYFKKYAVDFRNEGVRLLGGCCGTTPVQIKAFKAGISALEPLKTKVVTVHPEV
VHVSEAAEPPESALYQKSVHGRSVFVEFDTPRHLNTDHFFRGVQALEAAGADAITMADNS
LASPRISNAAIGKLVKDRFHMPPLVHLTCRDRNLIGLQSHLLGLDVLGLHDLLVITGDPT
KIGDFPGATSVYDVSSMELIKLIKQFNRGISYSGKSLKKPTHFRVAAAFNPNVRNLDRAV
QRLKRKIECGADYFISQPVFDKERIIAISEATRDISAPIYIGIMPLTSARNAEFLHNEVP
GIRLPDDVRAKMAATSGKEEARQVSLDICRELIDTAMAHFRGIYLITPMSHYSMSVDLVK
YIKKKEREYTTLENSENMLL
>A0A6P0B056|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MAMSQAIHLRDQSDVLDDFSVEVTTKDTARLAAMSGAIPKGTIISIPFLSTESDADRIRA
AKMVRQAGYVPLPHIAARRLGSESMLSAMLSALVNDAQVSRLLLVAGDADPPKGPFLDTA
TILRSGILEQHGISNVSIAGHPEGHPVQNAAMLTSALLEKRLIMEAANIEWSIFTQFAFA
SEPVLAWIGELRRLGIEVPIHIGIPGPASVRTLLKFAAVCGVSASTSVLKKYGLSITQLL
SSAGPDALVNEYATGLSNAEYGDVRLHFYPFGGLHKTVDWLQEYRTRPS
>A0A8D2K5C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Theropithecus gelada|TrEMBL
MDHRKARVLPAGHYCPSLGIWASQAGSVRFSVPPSISRNLAMVNEARGNGSLNPCLEGSA
SSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPK
GHPEAGSLEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPVVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDALELLNRPTQNERETEAP
>A0A4Q7DPW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus sp. S-13|TrEMBL
MKISEIYEQKNKRNQTVISLEIFPPKTLNGEKTIFDTVTNLTKKPDYISVTYRDVTGDKT
REIASKIKQTTGVEVLHHLTCVQKSQGDIDEILNQIKEANIQNILALHGDYPKNQENYST
SDEYPLAKHLISDIKKRACFSVGAAAYPEGHVDSNSISENIDHLRQKYEAGTDFFISQLF
FDNDKFYRLNEAAKTARIACPLAAGIMPIMSAANIERLIFFGASIPTNLIKIINKYKESP
EDLRKAGLEYAFKQVDDLIAHGVDGVHLYTMNRPSVANEAMERYL
>A0A7K3VIC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MMIAPQSESREGAPLADLLSHYSIEVTSRDLQSLESMTATLPQGCEVFIAHLPKEDIGLL
VRAAAGLRDAGFVPIPHIVARNIRNRLELDTMLARLSEEAGVRHALVLGGDRDDAAGAFG
SSLELIETGLFQAYGIDRIAIACYPEGHPRIAGAILDAALTAKIDAAARAGLDVLLVSQF
LFDPKPLLNFARRLRERGVTAPLSVGIAGPASRTKLLKYALRCGVGASLRALRERSEIAR
NVLSGETPEELLMEIAAAQATEPDLGISGVHFFTFGDPAQSIRWAEQQVDR
>A0JXH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. (strain FB24)|TrEMBL
MSPPSLIDTHPNLSDAAPVALSYELFPPRSPAAAESLWTTIGELEATDPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPEELSEIIGELLDVGVRGILALRGDRPKD
GAAPVSGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPTEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLITRARRAGVTIPIIPGVMPLTSVRRLNRLAELTGVE
PAPELMARLAAADTDAERRLIGVRATVDLANAALDAGAPGIHLYTFNEHACALEVLDKLA
LPRPARPASRLNAIARRHQEMAS
>A0A3M8SXE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter psychrotolerans|TrEMBL
MIPISFEFYPPKTDEQRSQLDKTAAKLKGRSPDYVSVTFGAGGSTLSHTPEAIQHLRGNH
GLNAAPHITCMGGSREEIRGLLKLYRALGAKRLVTLRGDLPSGMVSPGDLRYASELVEFI
RAETGDHFHIEVAAYPEMHPQARDAHVDLDNFVRKVRAGANGAITQYFYNADAYFRFVDD
VRAKGIDIPVVPGIMPISNFSQIRRFSEMCGAEIPRWVSQRMVAYADDAESIRAFGTEVV
TQLCERLVAGGAPGLHFYTLNLAKPTLSVIDNLR
>C6W9J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101)|TrEMBL
MTSVLERLAGKTPAFSVEFFPPRDAADEQVLWRAIRELEALDPAFVSITYGAGGSGRDRT
IRATGRVAQETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDPNGEWT
AHPQGLNYAEELVRLCRELGDFCVGVAAFPYGHPRSADLDTDTEHLVRKLRAGADFAIAQ
LFFEADDFLRLRDRVVARGCDAALLPGLMPLTTPRTLAKTVELSGAPVPDSVARALDPFT
GDAAGFRRAGVELVTRMGERLLAEGVPGLHFYTLNRSKATREVVADLGLAPARTTA
>A0A2P5T0D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pantoea edessiphila|TrEMBL
MSDYYTDQQKKLSKVELKFNKKFNISFEFFPPRNKEMEETLWKSINFLSQLKPKFVSVTH
GANSGENRLTYSITKDIKDRTGLEVVPHLTCINYTRNELINIANNYWNNGICKIIALRGD
LPNKKNIKTNMYCYELIALLKKVGDFDISVAAYPEVHPEAKNAQADLLNLKCKIDAGANR
AITQFFFNIEHYLRFRDRCVAVGIDVEIVPGILPVSNFKQLRHFAKISKVQIPLWMYEIF
NGLDNDFETCKMIGAHIAMNMVEILSNEGVKDFHFYTLNRYEMSYSICHTLGIKPHKLFS
IQ
>C4R2L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Komagataella phaffii (strain GS115 / ATCC 20864)|TrEMBL
MTKIIDKIKELKGEPFYSFEFFPPKTDNGLRNLLARLGRMSMLNPLFVTVTWGAGGTTSS
KTLDLAITCQKDLDLTTCIHLTCTNTSKKLIDNALKAAYDNGIKNILALRGDPPREAQEV
AVDQDFKYAIDLVRYIRGQYGDYFCIGVAAYPEGHVEGNDDSEQSIDHDMPYLLEKINAG
ADFVVTQLFYDADKFCTFYNTLKQRLGRDVVVIPGLMPINTYQLFQRATNLSHASIPPAV
GQLFPPDVRHDDDKVKDIGVKLMIDIVDQIYNETHGEVNGYHFYTLNLEKSVAQIVDKSS
LLSPRLTVSSRFENAIESSSEDEKEQNQQTKTIIAISSGEGTMGKEATWDDFPNGRYGDS
RSPAYGEIDGYGPSLKVSSSRAYKLWGYPVDLDDITKIFIAYLSNRITALPWSELGLNPE
TGLIQEELIQLNEKHMFTISSQPSANGVKSTDKLFGWGPSEGYVYQKAFVEVFINKKQWN
EEILPNLQGHKSVTWYLGDCNNAFDTNIKIPLSSNSVTWGCFPDKEIVQTTIIGEESFQA
WNEEAFNIWREWQKLYPKNTASYNLLGSIINNFYLVTLINHDYANDNNNLWEILLQ
>A0A4U6C0R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquamicrobium sp. LC103|TrEMBL
MAPGEAQLKEEWSALPALLENYSVELTARDRRSVADVAAHLQRGVEVFVANLPNESADVL
VEAVTALREAGLVPVPHIVARNTRHAHELDETLGRLVKEAGVDRVLVLGGDRDDPVGEFT
SALQLLETGLIQKHGIRKIFLACYPEGHPRISDTVLQEALKAKLAAAREASLEVTLVSQF
VFDPKLVVELAKWLRANGIEAPLRVGVAGPADRGKLIKYAIRCGVGASLRILKERGELAK
NVLAGETPDELLGEIAEAQAYDPSLGIDGAHFFTFGDPVKSARWVEGQR
>A0A086B8H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium piperi|TrEMBL
MKITEHIRKANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIEN
IMALRGDAMKGHQYFEATPGGHESAMDLVHQINDLGRGKYLHNEDQICDELNKFCIGVAG
YPEKHIEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITIPIIPGI
KPIATKKHLKLLPQVFKIDLPEELINEVESAKNNEVVRQIGIEWAINQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A3A6IBH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium TF09-2AC|TrEMBL
MKTSEFFKQKTVLSLEVFPPKRTAPVDTIYKTLDELKGMTPDFISVTYGAGGSENSRATL
EIASSIKHRYGIESVAHIPCLHLTKEDAAEILLQLKAHQIENILALRGDRIPDREPAGDF
KYAADLVGFIRDHGDFNIIGACYPEGHQESGGLVRDIHNLKYKVDAGVSRLITQLFFDNG
YFYRFRERLDLAGIRVPVEAGIMPVVNKKQIERMVSLCGVRLPKKFTSMMERYGDNPVAM
RDAGIAYAVDQIVDLAVHGVDGIHLYTMNNPYIANKIHESVFRLMAS
>A0A3S7KBX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. SAU14A_NAIMI4_5|TrEMBL
MTAISFEFYPPKTDEQRGQLDRAAARLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAPDALTDLKHFKAKVDAGADAAITQYFYNADAYFHFVDE
VQRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMLAYGDDSESVRAFGAEVV
AKLCQRLVAGGAPGLHFYTLNLAKPTVSVLKLLNG
>A0A1V2H638|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas deserti|TrEMBL
MNHLADHAAASGAPKGTLQRWLTGPRVAGLPVPTELPPPALSFEFFPPRTEALEQQLWTN
IRRLEPLAPRFVSVTYGAGGTTQERTHATVARLVRETSLTPAAHLTCVGASRGEVDEVAR
QYWDAGVKHIVALRGDAPAGEAGYTPHPQGYAYAADLVAGLKRIGDFEISVAAYPETHPA
ASSAESDLDNLKRKIDAGATRAITQYFFDTEVFLRFLDRALAAGITVPIVPGILPVSNFN
QVKKFSAMCGTSVPVWMGKLFEGLDEDADTRRMVAAALAAEQVRLLQANGVDEFHFYTLN
RADLTFAIAHILGARPKAV
>A0A855MD40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium versatile|TrEMBL
MIITVTVNGVAGMSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWSSIDRL
SSLKPKFVSVTYGANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWE
SGIRHIVALRGDLPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLIN
LKHKIDAGANRAITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTN
VRVPNWMTTMFDGLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICH
TLGVRPDVAR
>A0A6H1UFY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrimonas lipolytica|TrEMBL
MSFHHAQQIEALNERLSSLKDINVSFEFFPPNSETMEQTLWQSIERLAPLKPKFVSVTYG
ANSGVRDRTHSVIERIHQQTDLQAAPHLTLVDASDEELRQLARQYWQQGVRHIVALRGDV
PDGQPNPNRYAADLVRLLKQEHDFEISVAAYPEVHPEASCGQSDLVNLKRKVDAGATRAI
TQFFFDIEAYLRFRDRCAATGIDVEIVPGILPVTNYQQLLKFSQFAKVRVPNWLHHMFDG
LEDDAATRKLVGANVAIEMSKVLAKEGVSDFHFYTLNRAELSYAICHALGVRSGLN
>A0A7Y3S9Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sophorae|TrEMBL
MALKNEARGRNIRVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTRAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPERHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIDDLVRRGIHDFHLYTMNRAPLVSAVLDNLGLSRRAPKSAGAAA
>A0A7L3K2W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drymodes brunneopygia|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLRDKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYAADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7L7IPB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. RHBSTW-00175|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFAGMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A7Z0QPJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas deserti|TrEMBL
MIPISFEFYPPKTEDQRTQLDRSAKRLAGHAPDYVSCTFGAGGSTLSHTPETVRRLKQHH
ALDAAPHVSCVGGSRAEIRALLELYRTLGCRRLVALRGDLPSGMGRPGDLRYGVDLVAFI
RSEFGDAFHIEVGCYPEVHPQADDALADLRHFKAKVDAGADGAITQYFYNVDAYFHFVEA
ARRAGVEVPIVPGVMPVSNFAQLRRFSEACGAEIPRWMQRQMTAHGDDADAIRELGADIV
ARLCERLIAGGAPALHFYTLNLSRPTQAVLARLA
>A0A845EX32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus hwajinpoensis|TrEMBL
MSLLEDLEHKILVGDGAMGTLLYSYGIDQCFEALNLSHPDQVLNVHQAYVHAGSDVIQTN
TYGANYSKLSRYGLEDLVKEINKEGVKLARKAATDSTYVLGTIGGIRGINTRSTPLDEIK
RSFREQLYCLLLEGVDGLLLETYYDLEEIITVLKIARKETNLPLIAQVSMHEPGILQDGT
SLAAALKQIENAGADVTGVNCRLGPYHMIQSLEQVPLSGRFLSAYPNASLPDYEEGRLVY
PTAPDYFKQSAEALRQQGVRLIGGCCGTTPEHIAAAANALKGLKPITTKEVTVNEKEARI
IDFEEERLPHLHEIARKQRSVIVELDPPKKLSIDKYLEGTKALQEVGVDAITLADNSLAS
PRICNTAMASTIKAQHNVRPLVHVACRDRNLIGLQSHLMGLHTLGINQVLAVTGDPTKIG
DFPGATSVYDVSSFDLIRLMKQFNQGRSYSGKSLEIKTSFSIAAAFNPNVRHLDRAVERL
EKKQQCGADYFISQPIYNEAQLLEVYEATKHLTCPIYIGIMPLTSYRNAEFLHNEVPGIK
LSDSIRNHMLHAKDSTQSIEAGLAIAKSLIDAAFDLFNGIYLITPFLRYELTVELTRYIN
EKTRLEEERKNRNGLHLI
>A0A2A4G5S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sediminicola luteus|TrEMBL
MKVTEHIQKAKGETLFSFELIPPVKGKNIQELYDNVDPLMEFKPPFIDVTTSREEFIYVE
KNGLLDKRITRMRPGTVGICASLKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIENV
MALRGDAMKEQRYFEATQGGHLYAVDLVKQIKEMNQGAYLHDVVETSNCSNFCVGVAGYP
EKHLEAPSLKSDLKRLKEKVDQGADYVVTQMFFDNQKYFEFVAAAREIGIDIPIIPGIKP
IAVKRHLQLLPQVFKVDLPEPLIEAVEACADNKAVRQVGVEWCIEQSKELKAAGVPVLHY
YSMGKSDNIYQVAQALF
>A0A135HUC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paramesorhizobium deserti|TrEMBL
MSVFGLSRRPDIGQTTRVSFEFFPPKTEEMEKRLWETVTRLAPLKPEFVSVTYGAGGSTR
ERTARTVARILKETDVTPAAHLTCVDATKEEVDTVIREFSALGIKRFVALRGDPAGGVGD
QYRPTPGGYFNAAELVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPILPGVLPIHNFKQVTNFCSRAGTHIPAWLAERFD
GLENDPQTHMLVAAAVAAEQVLDLVERGVQDFHFYTMNRADLAFAICHLIGIRPHKQGVE
NEPTKAVSPDLAGAAA
>A0A095AVJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter tropicalis|TrEMBL
MSLSRLSVELIPRSTEALLDDVASVKALFPAADTLNVPDLMRFPLRSWDAAALIRPHFAR
VVPHIRAIDVAPDAPLPGADQPGLEDVLVVHGDPPADLSHRTYPNSTESIIRRYKKEAPH
LRIYAAFDPYRRAPWQELEDVARKKEAGAEGFFTQPVFDLKLFDLCREWLRDETVFWGLS
PVIGPRSRSYWETTNHVVFPKDFEPTLEANIHFAQTVLRHLSQEKGRAYLMPLRVKLDQY
LPPLLEALA
>A0A1C2AI43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagibacteraceae bacterium GOM-A1|TrEMBL
MNFSLEIGPKTDLSTLPKVKDVYVTMLPGGDYKETAQQSGELVKEGFNPVPHFPARSIND
ENQLKDYVSRCKDLGVKQVLVIGGSRDPIGKFDSSYQMLETGFFDGIKIGIAGHPEGSPD
ISDSDLEKAMIDKKPYADYIVTQWLMDTQPIIDFISKQTIPVHVGITGPMKISSLIKFAN
IVGAKNSINFLKSNFSKALDLLKPKDPNDLIGKVKSHTDYFHIYTFGGLKETNKWLKENN
YV
>A0A1V2IVN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. BMG5.30|TrEMBL
MTAVRSVVATRGLAATRGLTVRDCLDSGRPSFSFEFFPPRTPEGERHLWTAIRELEPLRP
SFVSVTYGAGGSTRAGTVRITERIATETTLTPIGHLTAVNHSVAELRQVIGSYAGAGVRN
VLALRGDPPGDPQGEWVAHPQGLHHAEELVRLVQSLGDFCVGVAAFPDRHPRSSDFDTDA
RYLVRKLTAGXDYAITQFFFEADAYFRLVDRVRRLGCEAPIIPGVMPVTNVAQIERMAKL
SGAAFPPGLARRLHAVADDPAAVRAVGVEVAADLCEKLLAGGAPGIHFITLNRSTATREV
FHSLRR
>A0A2N8UNA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporisorium reilianum f. sp. reilianum|TrEMBL
MASPSAAAPAAGASSSDPAHITSKIHAASARDAPFWSFEFFPPKTTQGLANLYNRIARMR
ANLDPSWIHVTWGAGGTTGGKSLELAGRIQKGKLDPDVEVVQNEVKQIGSGAQQHIENVQ
GGEPWEQAGPDACDVCLHLTCTNVEKSSLDQTLETAKRLGIKNILALRGDPPRGEEYWVA
ADERFQHATDLVRYIRHNHGDFFCIGVAGYPEGHADYVDRDVQRDLRYLKEKQDAGAQYI
VTQLFYDVDQFLSWYKDCRDIGITIPILPGIMPVQNYSSFRRMTNLCKVQVPQLILDALE
PIKSDDAAVKEYGVSLSIHMVGRIFLESDIRGFHLCSLNLEKSIERILEGLGWKTDLGAQ
PEGEARLRGIPAHLHLEATKNQMLSDRTGANTPKDFKVTTQEALARTLARTSSSYQVPET
STWDEFPNGRYGDSRSPAFGEMDGYGVSLKVPPQDALRIWGHPVTLVDISKIFASYLEEK
ISCIPWCDAPLMNETLQIRDHLLSLNRLAEGASQSGKGWWSVGSQPAVDGAPSTDPTFGF
GPPGGFIFQKSFVELFMSTADKDKLVARIDALGTNAQITYFASNARGDFQSNLGDGEANT
VTWAVFPGKEIVQSTIIERESFEAWRDEAFEIWGEWSLLFPKQSASRKLIEQIKDGRWLV
TVVHHDYKQTEALWHFLAE
>A0A2G2D5C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea sp|TrEMBL
MTQPDTNPHDPSALLEPLPGHSSLGRLERILRRGEFAVTAELNPPDSANPHDVYERAAIF
DGWVDGINAVDASGANAHMSSVGICALLTRMGYASILQISCRDKNRIAIQGDVLGASAMG
VQNVLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNSKFLSGRKLTSPPTVFLGA
AINPFAPPHDFRPHRLAKKIAAGAQFVQSQYCYDVPMMRAYMQQVRDMGLDQECFVMCGV
GPLASARTAKWMRSNVPGVHIPDHIIKRLEGAEDQKKEGKQLCIDIINEVKEIEGISGIH
VMAYRQEEFVAEIVHDSGVLKGRRPWRKEPNPVDQMVAERMEEILEEPKHMLHEMAGAAG
DADAQD
>A0A372Z191|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AM16-13|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>D5AMW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)|TrEMBL
MTTPHVSFEFFPPQTLDASFRLWETAQVLAPLKPGFVSVTYGAGGTTRKLTHEAVAAIHK
NYGLNVAAHLTCVDATRAETQEIIDAYAEAGVTEIVALRGDPPKGAARFTPHPDGFASSV
DLIEWLARDGRFTLRCGAYPEPHPEAADTLADVRWLKRKCEAGATSAITQFFFEAETFFR
FRDACVKEGITAKIIPGILPIQSWKGAKSFAQRCGTSIPTWVEEAFDHAIRDDREQLLAT
ALCTELCDNLIAGGVEDLHFYTLNRPQMTRDVCHALGVNPGVVLENVA
>A0A1E7PUJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. X15-166B|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGREKLQVVRDQLAAVHPDFFSVTFGAGGSTRERTVETV
LNLHQQGVSTAPHLSCVGATRESIAELLDLYRDHGINRIVALRGDMPSGMGASGELRYAN
ELVSFIREHSDDTFNLEVAAYPEFHPQARSAEDDLKNFARKVEAGANSAITQYFFNPDSY
FYFIDRLEKMGVTIPVVPGIMPVMNFSNLVRFSEMCGAEIPRWIRKQLEAYGDDTTSIRQ
FGEQVVTDMCQKLLDAGAPGLHFYTLNQAEPSVSIWNNLGLADREKIAF
>A0A2G2D2J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea sp|TrEMBL
MTSSFRSSAEALSERIKVSFEFFPPKNGNMESQLWESISRLAPFQPDFVSVTYGAGGSTK
QPTMNTITRISKETDLAPAAHLTCVGSDKASVDAVAREFQAVGVKHFVALRGDPPEGVGA
AYKPHPDGYANGAELVAGLRKISDFEISVSAYPERHPESPDFATDIDMLKRKVDAGATRA
ITQFFFDNDIYERYVERVRRAGIYIPIVPGILPIHNFAQVARFSKLCGASVPDWLARRFD
GLENDVDTRALVAAAMAAEQVNDLVERGIDDFHFYTMNRAQLVYAICHMLGLRGDEAGSD
DSGAVGAAA
>A0A060TI73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastobotrys adeninivorans|TrEMBL
MKVSKKLEAAHSEDKGPTKATFSFEFFVPKTSQGVQNLYDRMDRMYGLNPQFIDITWNAG
GRLSNLTCEMVSTAQSAIGLETCMHLTCTRMPKQLVENALRDAYNAGCQNILALRGDPPA
EGDWTPTEGGFAYAKDLVKYIRDSYGDYFDIGVAGYPEGHPEEPNPDVLIPYLKEKVDAG
ATFVITQMFYDADNFLEWVRKCREAGITVPIIPGIMPISTYASFMRRANWCEIKIPQPFL
DELEPIKGDDMAVRQKGTELVAKMCQKLLDSKLIHHLHFYTMNLEKATVMVLEHLDLLPT
REGPAPNRPLPWRQSLGLGRKEETVRPIFWKNRKQSYVFRTQDWDEFPNGRWGDSRSPAF
GDLETYGVLFRQTKDKALELWGKPESLKDLSILFENYIRGKIKALPWSDQAISEEVQSIR
DHLIDLNHRGFLTVNSQPAVNGVRSNHPVHGWGPSNGYVYQKAYVEIFVPPDMIDDVLKG
IERDSEITYYAVNNSGNLKTNSPVDGPNAVTWGIYPGKEVIQPTVVEKISFLAWKDEAFR
LGEEWANCFEPESPSRALVKGLVDSWYLVNIVHNDFQNPEAIFHVFDGLFANGIDRPVNG
ASNGVANGN
>A0A7C1JA65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGLREAFESGKFVVTAEVGPLKGTDITEIKEVAHLLKGKVDGTNVTDQQSAVMRLGSMVT
CYLLKQEGLDPILQVTCRDRNRLAIQSDLLSAHVLGIRNVLAITGDYPTLGDHPDAKAVY
DVDSVQLVWMINRLNQGYDVAGNELQGKTDFFIGAVVTPITDTEAAFELQLIK
>A0A7V9SZX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MHELLAAGQTFSFEFGPPRTEQAERTLEKTLVELEPLAPSFVSVTYGAGGSTRDKTREIV
EHIHRDTSMAVMPHLTCVAHTRGEITEIVEGYRDQGIASILALAGDPPLDGGPVSGDFRY
AIELIELVRELGDFSIGVAAHPELHPRSAGDRAADRRHLAAKLARADFGITNLFFRATDY
LTMVDELDALGVRTPVLPGIIPVTNVAQVERFATLSGAAVPAELADRLHAVADRPEEVRR
IGVDVAAALTAELLERGAPGVHFYTLNFSRATKEIYAALGKGPAAST
>A0A7D6TBX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia rettgeri|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSAEMEQTLWKSIDRLKVLKPNFVSVTY
GANSGERDRTHSIIKDIKDKTGLVAAPHLTCIDASPDELKTIARDYWNNGIRHIVALRGD
LPDNSRKPDMYAEHLVELLKTEADFDISVAAYPEVHPEAKSAQADLINLKKKIEAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKITNVRIPSWMNRMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPK
>A0A7C3A7P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
ARFMKRAEGFGVPVLAGIIPLKSVGMARYMNKNVAGVFVPEHLIEEMSKAENKAQKGLEI
AARLIKDLKDLCQGVHIMAIGWERKVPEILELAGLA
>A0A7C2PS19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MFEAFCKNLHNDEPFITVEVNPPHGASLDPIIEEIKKSNLAEKVSGFSCTDNPLAKLKMS
GVLSAIKLQQTFGKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKLSDQPE
VKGVVERDSTLLLSIIYHLNKGVDYSNKPLNPAPKPIYPFAVANAYAKDMKKLQKRIIKK
LNYGARAIITQPVYDLENAKELLELFEEAKEISIRDTAKEAQLILGQFPIVAARTANFID
DKVPGISVPKEIIDEMNLAAMDGPEREKEVGFALSKRIFDEMMKLHGKVHLMTHNRFDLC
SELIG
>A0A7U5Y265|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. YMA4|TrEMBL
MTDHNFSIEFFPPKTAEGAEKLRATRAKLSELHPKYFSVTFGAGGTTQQGTLDTVLEIMA
AGEEAAPHLSCVGGTRESIRAILQQYQAHGIRRLVALRGDLPSGYGAAGEFRYASELVEF
IRAETGDWFHIEVAAYPEVHPQAKSPQADLDAFVRKVNAGANAAITQYFYNADAYFQFVE
QAHKAGVTVPIVAGIMPITNTTQLMRFSDMCGAEIPRWVRLKLSSFGDDTASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQVAPTTALWQRLVK
>A0A7C3N2V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSRLERVLEAGHFAFTAELGPPQGANIEVIKKKAGYLKGVTDAVNITDNQTAVVRMA
SWAAALIAIQEGLEPNYQMVCRDRNRIAMQSDILGASAHGIRNMLCLSGDHQQFGNHPAT
KGVFDIDSIQLISMVKGMRDEKKFLNGDPIDGPPLLYIGAAANPFAEPFEWRVHRLAKKV
EAGADFIQTQCIYDMKRFREWMKQVNDMGLSEKVHILAGVTPLKSGGMARYMAKNVSGII
IPEEIINRIVQAKKAADEGIKLCVEQIEELREIKGVHGIHLMAIEWEHRVPEIAERAKLI
PRPAV
>A0A2A3MZJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. D43FB|TrEMBL
MTLNDPAAPLYADLAGDCQVSFEFFPPKSEKMEAQLWSAIETLTPLAPKFVSVTYGAGGS
TRERTHNTVARIAQETPLAAAAHLTCVGASKDEIGEIADAYWDAGVRHIVALRGDPPEVG
GTFEPHPLGYKGAAELVEGLIKRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGAIR
AITQFFFTPEAYFRFLDKVLAAGITADIVPGIMPVSNFAATQRMAAMCNTQVPSWMARLF
EGLDDHPASRQLVSATIAAELCQKLYAGGVRDFHFYTLNRSELSFAICHLLGLRAKATAD
VAA
>A0A7C4DKM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MMAKYMRDKVPGITVPNELVTRLEKCVEGIEDKKERSKRIQQEGVKIAAEEIHQVMEIPG
VHGVHIMAVAWEEIVPEVVKAAGLDKERPKYKP
>A0A243DQP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis subsp. darmstadiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>V7DD73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas taiwanensis SJ9|TrEMBL
MSLLKTALRENTFVCVMEFVPKPSTERFAAMDAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAGKHQEAMHWMSRQATPRPMLACLMSLTHGRATMLEHVAGVTVTPSMRDMLEAEAAQSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGVHELKQLLALEARIEHWQAQIHTLEQWAPA
WQASWQMPGLPAVSFHPPQASWRQGESRVDASFKEKARYHLMHGMHSLLFSRRNSLSKAF
GWAVRQPMWATRLGSQVLHKVEHAVKHPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTALLTERLIPCIELETRHRSSWPQWFQAQTP
RQLSPQPAPRTQPES
>A0A2E4F9W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MDAKELQARVASGVLIGDGAMGTQIYDAGVAYEHCFDELCLSRPSLIHETHRRYLAAGAQ
VIQTNSFGANAIRLAEHELEGQLEDIARKSVVLARDVADSQPGTLVAGSVGPTGSIMAPI
GKLKPQEAEDAFRPQVAALAAEGVDFLLLETFMDLREIEAALRACAAEAPGLAVAASMSF
TDEGKTIYGYKPEGVARALSDQGAAIVGANCSVGPASLMDVLERMVKRVPGLTYMVQPNA
GLPTYHGGRYIYVSSPEYMASYASDFVDLGVGFVGGCCGTGPEHVAEIAANITGRVPQPP
AVGSLDIEVYEADEIAQTTSLVASGVQEKLDAGEFVVSVEIDPPKGIDATKLIHGAAQCR
LAGVDAINIADSPLARARMSALSLANLIRAQVDIEIILHMSCRDRNLLGLQSEMMGAYAM
GIRNILGVTGDPPSIGDYPHATGVFDVDAIGLTSLLARLNEGVDLAGKKLKYRTNFHLGV
AVNPTTPDLETEFRRFQQKVDAGAQFAMTQPLFELEPMERFLEKCKPTIPILAGILPLRN
YKHARFMHNEVPDITIPESFRERMLEAGPDGPQEGVAIAREFFEQIRPMCQGIYLMPPFD
RFEMAVDIVDGLIEPT
>A0A496ZCI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MQKCEVIFARALNALNSSPNGVGSSTMLRVFQNDLFLPEDFITTLELVPGKDSSGRSVDT
VMGIARDSFSDGGLSAVSITDNPGGNPSLSPDVLGHDIFKVGMDVIVHFTCRDLNRVGME
SRALQLSMMGMKNLLALTGDYTGKGFGGQGAPVFDLDAVNLLMMLDHLSHRFHENGDPDG
FFAGCAVSPFKYTEAECFAQYAKLCRKISAGARFIITQLGYDARKFAELITVLKQLEVNL
PVFGSIYLLTPRSARIMNKGMVPGVVVTDKLLTRVLDEWKNPKAGRVKAIERAAKLGAIL
KGLGYQGMHLGGIHKTFDVAGDVMSHMKAIQDQWQSFLPEFEYPVTNGFYVFPDDISEKL
PANSFGQQTSIPMLEKIHFRLMKSFHNRFFSFESKQARTLEKVCGWIDHHRMAEGIVTLL
ENSAKKLLLGCQHCGDCGIQNLAFLCPESRCPKHTRNGACGGSSDGKCEVRTDRNCVWVR
TYRRMAYSGTCQNLLSGCVPPRMWELNQTSSWLNFHLKRDHQSVSTGLEKYCRLEDCQLS
FCEHYGKPLNPKG
>A0A7C1CGT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEQQVKDCFETTSSTFSFEFFPPKEEKDWDKLFHTIKDLMPLKPSWVSVTYGAGGSTREN
THNLVVRIKRETELMVVSHLTCVGTDRNDIHSILERYVHHGIENILALRGDPPAHQSAWV
PTRDGFPHAADLVSFIKKQLPHLCVGVAGFPEGHPETPNRLLEIDYLKAKVDAGADYIIT
QLFFDNRDFYDFCQRCELAGIHVPIIAGIMPIISKSGMLRMASLAAGARFPAELLRSVGA
AQDAASIEQIGIEWATSQVRDLIDNKVKGVHFYTLNHARATLKIYESLGV
>A0A7C3U2P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSIQRRLQNGEFVVLAEMHTPKGVDISRLITDAKRIKGRVHGILVPDMDNGIMRLSALAG
GALLQQEGIESMITVYGRDRNRMALQGDLLAAHVLGIRNLVVAKGEVMANSDHRNALPVN
DLDELGLLETIRTLQDGKDLSGFDLNGSPEFFVGCYLSPFADEAALDRELRSAAEKVQAG
ARFLITPPVYDLAHFEGWLKKASALKVPVIAPVFLIKSVAIARYILTNEPGSGLKEDVIT
RIRKSSDRELEGIKIAGETVAGLKKMAQGVLIQTMGWEHRLPAILDQAGL
>A0A8B3FKN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacterium australiense|TrEMBL
MVTSSSLTGAGTLVCVQHEYRPNAVAPQDRLDFCPDETIAQLLARADRPTISAEFFPPRD
DEGQAILHRAIERLEPLHPDFVSVTYGANGSSRERTLDAVRDILASTRLRVMGHLTCTGQ
SVDELRVVIDSYGEMGVRHILAVRGDMPGGPLVPWQQHPQGLSNATELVELIKSRGEFCV
GVGAFPDVHPGSTAENDVRVLCDKQAAGAEFAITQLFFRPAAYHRLVDRLRVAGCRMPII
AGMMPVTNIRQVDKFAELSGAPLPDEMVTRLQAVAEDPEQVRSTGAQICAELARELLAGG
APGIQFFTQNRSAATRRILAMLESGAR
>A0A661SLK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MESSSRLQQVLSKGGFAVTAECGPPRGADTQVVRKKAELLKGCVHAVNVTDNQTAIVRMS
SISASVLLLQMGLEPVMQMVVRDRNRIALQSDIMGAYALGIRNMLCLSGDHQTFGSQPDA
MNVFDIDSMNLIHTVRTMRDEGKDMSGFELNEPPRMFIGAAANPFADPFEYRVIRLAKKI
DAGADFIQTQCV
>A0A661MPP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MMLREKLDQGGFAVLAEFEPPKGADFSEMLTNAVNVKGRVDAFVVPEMANAVMKASSLGG
CLFLQTNGMQTVFQVCCRDRNRLALQADILSAAALGIPNLMVVKGDDITVGDHPQARAVN
DIDVFQLLEVIEQMRNGKDMAGIELKGAPDFFVGAFFNAGAQGGLLDLEFEELEKKIDLG
VKFVITSPVFDLKILERILKRLSKDKVALIPKVLLLKSAGMARYINRNIKNISIPENLIK
SIQKAPDKPRECVKIAADMIKQIKGLELPGVAISTMGWEDKLPQILDESNIL
>A0A661QCD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MMLREKLEQGGFAVLAEFEPPKGADFSEMLTNAVNVKGRVDAFVVPEMANAVMKASSLGG
CLFLQTNGMQTVFQVCCRDRNRLALQADILSAAALGIPDLMVV
>A0A661I624|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MLKDKIKNRQGDILFYGMTPPKAKHTKDELKSIAAKHIERIKDLDIDGLVLYDIQDESDR
TDMKRPFPFMETLDPCDYAKNYLDAPLHIPVIIYKAVGKYDKDEFKEWLENRKGRDFFSV
FVGAASKQTKVTIGMKEAYELKKKVNDDIILGGIMIPERHSIKRDEHLRVFSKIDNGCEF
FVSQCVYDLMGAKRFLDDYLAYSKEHNKPLAPIIFTITPCGSAKTLDFMKWLGINIPEHL
ETRLKNSENILEDSVKLSRDIFEILYFYGKGKGIPIGCNVESVAIRKEEIDASIALLHDI
SKIMER
>A0A661LPP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MALRESLESGKFAITTEVGPLKGTDTSEIVELAEILNGTVDGVNVTDQQSAVMRLGSLAT
CSMLVQRGLDPVFQMTCRDRNRIALQSDLLSAAVLGIRNVLVISGDFPSLGDHIDAKDVY
DLDSEQLIWTISQMNDGYDLSGTELKGKTDLFVGAVVKPVSDTEESSELQLAMMEKKISV
GARFFQTQAVYDVDAFEKFMKRASQFKVPVLVGIIPLKSAGMARYMNKNVSGVFVPEHMI
SDMAKAEDKTATGLGIAASLIKDLKDLCHGVHIMAIGWEKKVPEILRMANLS
>A0A179HAY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Purpureocillium lilacinum|TrEMBL
MHIKDMLSEAEKGAQPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLEKVNDALSRAYKAGCTNILALRGDPPRDQDK
WTATEGGFQYARDLVKHIRATYGNHFDIGVAGYPEGCDDNKNEEELLDHLKEKVDMGATF
IVTQMFYDADNFIRWVGKVRERGITIPILPGIMPIATYASFLRRANHMQCRVPPEWMSVL
EPVKNDDVAVREIGKSLVAEMCRKLLANGIHHLHFYTMNLAQATRMVLEELNWAPSAERP
LQHALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTTVRDIANTFVKYLDQEIDSLPWSESPLTGEADAIRADLVA
LNKRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPPAIIDQMIARIDSKP
TLSYYAVTKDGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
AHCFDSNTPSRALIDKIMNEWYLVNVVNNDFHENHTIFELFKDLEVQGLDEAQAA
>A0A661QR16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSNLEKVLEAGHFAFTGELGPPRGTGAKEVTEKAQYLKGNVDAVNITDNQTAVVRMS
SWAACLLLIQEGLEPNFQMVCRDRNRLAMQADILGGYTHGIRNMLCLSGDHCMFGDHPDA
MGVFDIDSMQLINMVKTMRDEGKFQSGADIEDPPKIFIGAAANPFAEPYEWRVHRLGKKI
NAGVDFIQTQCIYNMDRFRKWVQQANDMGLTEKVYILAGVTPMKNVGMARYMQKKVPGIE
VPEEIIDRLKGVEKKKVADEGIKIACEQIEEFKEMKGVHGVHLMAIEWEHKVPEIAELAK
VLPRPKV
>A0A1H7QMM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseateles sp. YR242|TrEMBL
MTTPTTATTATTATTAKTATTPVSIEFFPPNTPVGSEKLKTVVQELRAVNPQYFSVTYGA
GGSTREKTLATVASIAGQGFDAAPHLSCVGSTRENIAEILATYRAQNVRRVVALRGDLPS
GTATAGEFRYAAELVSFIRQTQGEDWDIEVAAYPEYHPQQRYAARDLQYFADKMKAGANG
AITQFFYNPDAYFHFVDAVRALGVDAPIVPGIMPINNFSRIAQFSQRDGIEIPRWVSMKM
EGYMDDAASVRAFGLDVVTRLCERLIQGGAPGLHFYTLNQSALTLELCSRLKLSPAL
>A0A5P9CFE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio aquimaris|TrEMBL
MGYTHAGHIDALNQNIAELADNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAQTGLVAAPHLTCIDASREELIRIAEDYWANGIQSIVALRGD
IPPGGGKPEMYASDLVILLKQRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQS
>A0A661LDZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MALKETLDGGKFAVTTEVGPLKGTDISEIMELAEILNGKVDGVNVTDQQSAVMRLGSLAA
CSILVEKGLDPVFQMTCRDRNRIALQSDLLSASVLGINNVLVISGDYPTLGDHIDARDVY
DLDSEQLIWTINRMNEGYDLAGNELQGKTDLFVGAVVKPVSDTDESFELQLTMMEKKISV
GARFFQTQAVYDVEVFERFMKRAVQFKVPVLAGVIPLKSAGMARYMNKNVSGVFVPEHMI
DDMARAKDKVATGLEIAAQLMRDLKDLSQGVHIMAIGWEKKVPDILRLANLA
>A0A661R671|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MLRIFSHAISNPENFVVTLELVPGRESAGRSIDTLKGIAKDAFSDGRISAVSITDNPGGN
PSLSPDVLGYEIFKCGMDVIVHFTCRDLNRVGMESRALQLARMGMKNILALTGDYSGKGF
GGQGKPVFDFDSVLLTTLLKSLDQRLLASGDPDLFFTGCAVSPFKTTEAETLAQYGKLDK
KLMAGASFVITQLGYDVKKFKELITHLHQRGMNPPVMGSVYLLSPRSARAMNKGRVPGAH
VADTLFDQVIKEWGGSPRSGLKTAIDRAAKLGVILKGLGYRGIHIGGIHRSFKAVGRSWT
GWRKLRIPGKRMWENSTWPNPMPRSIIALIRSLF
>A0A135IBC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterovibrio coralii|TrEMBL
MGYSHASHLDALNQNLSDLNGDINVSFEFFPPSTESMEQTLWASVQRLKTLQPKFVSVTY
GANSGERDRTHSIVKSIKQETGIEAAPHLTCIDASRDELKTIARDYWESGIRHIVALRGD
LPEKSQKPDMYASDLVELLKGEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIIPGILPVSNFKQASKFAKMTNVRIPHWMNKQYD
GLEDDPVTRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYALCHTLGIRPTL
>A0A3M2LRA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces triticirhizae|TrEMBL
MALGNPSTMSGRAATVRDLLAAGKRSFSFEFSPPKTERGEKTLWNAIRRVEAVAPTFVSV
TYGAGGGSRERTVRATERIATETTLTPVAHLTAVQHSVAELRNIVGQYADAGIRNMLALR
GDPPGDPMAEWVRHPEGVSYAIELVRLIKESGDFCVGVAAFPEMHPRSTDWETDIRYFVE
KCRAGADFAITQMFFYPEDYLRLRDRVSAAGCATPIIPEIMPITNARQIDRFQQLSNTSV
PPELKRRILAVKDDPMAVRSVGIEFATELCARLMDEDIPGLHFITLNTSSHSTATLDVYK
NLGLHQRS
>A0A2G6N4J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MPMLSDDFVITIEVVPPGGPDPSPLIDTLASLSALPFSGFSVASNPVAKPRMSAMALCAM
IRKHLDKPAVLHLTTRDHNRLSLQGELWGARALGIDTVMLATGDLVAFDDRHATTTVRDT
DIYGLVRMARESGMQTGVVFDIHPERNGLSQAVAHLKRKVDAGAQFAVTQPVYDMAGADQ
IADATHDMRIPMIMGILPLRTPRHADFLHHKVAGIAVPESLRARMHMAEDPVKEGVANAR
EMVSAARQSFAGACIMPPFDHFEVMTDILFPDPGSISFNLKRTHRPPSTNNTPGKRTNDQ
SNNKGRHP
>A0A661RWL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSNLEKILRAGHFAFTGELGPPRGANDAAVREKAKFLRGMVDSVNITDNQTAMVRMS
SWAASLVALQEGLEPNYQMVCRDRNRLAMQSDVLGAYALGIRNMLCLSGDHQQFGDHPRA
KSAYDIDSTQLIQMVRKMRDEAKFQGGAEIDTPPKMFIGAAANPFADPFEWRVHRLAKKV
KAGADFIQTQCIYNMDKFRRWIQQANDMGLTDKVFILAGGTPMKSVGMARYMKLKVPGMD
VPDEIIKRLQGVDKKKVADEGIRIACEQIAEFREMKGVAGVHLMAIEWEHKVPEIAERAG
MLPRPQV
>A0A661QY26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEYKSGSNLEKVLKAGHFAFTGECGPPQGANVEKLKEKAQHLKGMVDAVNVTDNQTAVV
RMSSWAASLILLQEGLEPNFQMVCRDRNRLAIQSDILGVYSHGIRNMLCLSGDHQKFGNH
PQAKNVYDIDSMQLIHAVKTMRDEGVFLNGEKIDVPPRLFIGAACNPFADPFEFRVYRLA
KKIDAGADFIQTQCIYNMDKFREFMKRVVDMGLHEKCYILAGVTPMKSIGMARYMAKQVP
GMDVPDSLIKRLQGAGKGKVAEEGIKFALEQIEEFKEMEGVAGVHLMAIEWEHRVPEIAE
RAGMLPRPKL
>A0A3D5WCK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNNSSKLKRVLEGGGFAVTAECGPPKGANPDVVLKKAEMLRNKVDAVNVTDNQTAIVRMS
SIAACSLLKTAGLDPVLQMVVRDRNRIALQSDILGASALGIRNVLCLSGDHHIFGNQPQA
MGVFDLDSIQFVQVVRTMRDEGKILGGDGLSQPPDFFIGAAANPFADPFDFRVIRLAKKI
RAGADFIQTQCIYNLDRFERWIGMARDRGITDKAYILGGVTPLKSPGMAKYMKNKVSGMD
IPDEIIKRMEGVPKDKQREEGINICVETIQRLRGVPGIKGVHIMAIEWEEVVGEIVERAG
LLPRPVFD
>A0A4R9MHP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. USMB20|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDNLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVE
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDAIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAAAATRTICERLSM
>A0A7T0ZAV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter hepaticus|TrEMBL
MCSFSFEIFPPRKDENIKNLDAILDDLGQLSPNFISVTFGAGRSINSKNTLETASLIQEK
YKIPSIVHLPCIHSSKEKITQILQQCKDRQLNKILALRGDVCNNLEKSKDFSYASDLISF
IQKYKDFEIYAACYPEKHNESKNFIEDIHYLKNKVDLGTNKLITQLFYDNDFFYTFKQNC
ALANINIPIYAGIMPITNKRQVLKITQLCGSKIPAKFTKILEKYENNALALEDAGIAYAI
DQIIDLITSGVDGIHLYTMNKSRAAIKIYEAIKYLIKVS
>A0A644X8L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MTYGAGGTAQSNTVEIASRIKKDFGIESIAHLTGCTSTKEGMKRTLTSIKDSGIENILAL
RGDIPQEKLADKNWNPEYRYASELIDDIKAAGDFSIGAACYPEGHVDSINKVDDLKNLKK
KMDHGADFMITQLFYDNDLFYQFKEKLDLVGIEQPVIAGILPVLNIKQVKRIQEISGCNL
PPKFLRILDRYAHDPASLQEAGIAYAVDQIIDLLSSGVDGVHIYTMNKPDATRRIMENIS
CVRKAVCRKEPQR
>A0A7L1VQJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sitta europaea|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A524HNC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MPPVAPRRSPMPRLRELLDDGRVHVMDGAMGTELYNRGFFVNVCYDELNLTEPDLVREVH
EAYVAAGAEIIETNTFGANPVKLSSFGLEERTEEVNRAAVLIARAAVRGRASVVGAIGPL
GIRIEPWGPTSREEARAFFARQVRGLLEGEVDGFLLETFSDLDELHEALHAVRDASELPV
IAQVTIGVDENTTFGTSVETVATRLAEWGVEVIGLNCSVGPAVMLDAIERMAEVTDRPLS
AQPNAGLPRAVGDRRMYLASPEYMAQYAKRMIQAGARFVGGCCGTTPEHIKKIAGHVASL
QPRLTTVSTPTAEHAAHRVEPVPLASRSAWGRKIATGEFVTSAEILPPKGWDPAPMLEAC
RSLAACGVDALNVVDTPRAQSRMGALPAALIIQSKLGLETVLHYTCRDRNMLGMLSDLLG
AAAGGLHNLLLITGDPPTMGPYPDSTGVFDIDSIGLTNVAHRLNQGLDPGGNPIGAPTEF
VVGVALNQSASDLEREVSRYAWKVDAGAEFAVTQPVFEPDELEAFLERIADRA
>A0A7D0IJ75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAARLKDYGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQIPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
AKLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQG
>A0A845A2I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontixanthobacter aquaemixtae|TrEMBL
MSPTLNQMHEARTALDSPLFEGLPGDIDVSFEFFPPKTDKMGETLWQSVETLKPLGPRFA
SVTYGAGGSTRTRTHEQVVRIQNEAGIPAAAHLTCVAATREEVNEVARHYWEEGIRHIVA
LRGDAPDGGGAYSPHPGGYANAVELIAGLKDIADFEISVAAYPEVHPDSPDAQADIENLK
AKFDAGATRAITQFFFDPQCFFEFRDKAAAAGIKGEIVPGIMPVMSFAAVQRMSGLCGTA
IPNWMEGLFDGLDERPAARQLVSATITAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GMRPTGGVK
>A0A8E3U6Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAPGTQRAEAFINTFSLEVSAKAMPALRAEAGRIAPGTTISIPYLANEDDDARLAAART
VRELGFEPMPHLSARRIASRAALARFLERAASEAGVETCLLIAGDLSTPAGPYADSTSII
ETGLLERYGIKVVAIGGHPEGHPVMNAEDRWRVLERKCQAIEARGMAPLIITQFAFDADI
VLAWLDALRARGITVPVLVGVPGPASIARLARYAAMCGVSASASMLARYGISIGRLLGTA
GPEVFVDRLLSGLTDAHGPVSPHFFPFGGIAPSLDWIERYRRRTSAASV
>A0A6P2A3Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thioalkalivibrio sp|TrEMBL
MNKATRNTPVFSFEFFPPKNAEGVERLRRARQRLTTLQPAYFSVTFGAGGSTRDRTLETV
LEIQRDGRVEAAPHISCISSSRGELLELLQTYRDNGVRRLVALRGDLPSGTGGRLGEFRY
AAELVAFIREHFGDQFKIEVAAYPEFHPQAANAEKDLEHFRQKVAAGADSAITQYFYNAD
AYVAFLDRVRAMGVQIPIVPGIMPITNYTQLARFSDACGAEIPRFIRKRLEAYGDDTASI
RAFGIEVVTRLCARLLEDGAPGIHFYSMNQAAAAEAIWKNLGLGELRASA
>A0A645G9Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MLALRGDRPQNDTCISEEAQYEYARDLIAHIRNFGGFSIGAACYPEVHIEAGDSLSDLRS
LKAKVKSGADFLITQLFLDNNFFYDFKEKLDLIEVNIPVSAGIMPVINKKQIERITGLCG
ASIPAKFKRILDKYENNPEALKEAGIAYATEQIIDLLSSGVDGIHLYTMNKPEVARKIIG
QISNIRSYLGNNIKYA
>A0A7V9PJD7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
EEGETQFAVDLREGRWVMSIQLDPPLGSSYAGLLEVATAVRDSGLGAYVDINDNATARVG
MNPLIVAAAIERTVGIETIPHLTPRDTTIMGLESVLLGTHAEGVRNVLAVTGDPPEVGDY
PGSGGVYEVDAIGLTHLISRLNQGENYNGKAIDAPTSFFIGVAVNPTADDLDLELDRFRR
KIEAGARFAMTQIVFELNHLERFLDRLGGTPPIPLLLGVFPLTSYRLALRLDNEVPGIIV
PEPLQEQLRDAGPREREVGFAHARDLLAAARGNVAGVYVVAPYRQPLSVLELLA
>A0A651HCJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MRAPPGSTPPPGTPPPLPPPSVPGVSAASPSLRDLLADDAVHLMDGAMGTLLYDRGFFLN
VCYDELSLTEPALVEAIHREYVEAGARILETNTFGANPVKLSSFGLEDQTEAINRAAVER
ARAAARAAGVPGILVLGAVGPLGIRIEPWGPTAEAEAEALFGRQVDGLLEGGVDGFLLET
FQDPGELRQALRAVKARSSLPVMAQVTIDEGGRTAYGTDVEAVARKLEEWGADAVGVNCS
VGPAEILEAVERMAEVTRLPLLAQPNAGFPRTVGDRKMYLASPEYMARYARRMVEAGVRF
VGGCCGTTPEHIRKMAEALAEVGPKTGTKGTAGVDGEGGPPQRSAPGSDSPAIPEMQDPI
PLRERSPLGRKLAEGTFVTSLELVPPRGWNAAGLLAEAREVRMAGVDLVTLPDVPRGLSR
MAALPAALLVTRETGMEVLAHYTCRDRNMLGMISDLLGAAASGLRNVLVVSGDLSPMGPY
PDHTTIFDIDSIGLTNVLARLNRGRDPGGHAMDPPTRFVVGVVLNQGAADREREQNRFHW
KVEAGAEFAVTQPIFDPTALVSFLDEAAERTPSVGDLPILAGLWPLSSLRNAEFLANEVP
GVSLPPAALERMREAEASGGPEGAASEGVRIAVEALEAVLPRIRGVHVSAPRGRVDLALR
VIEEARALLRNTPSG
>A0A7Z2G6E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia acidiphila|TrEMBL
MKPIELSFEFFPPKTPDGVEKLRATRAQLATLKPKFVSVTFGAGGSTQQGTLDTVVDIAK
EGIEAAPHLSCIGSSKESLRAILGEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVAF
IREETGDAFHIEVAAYPEYHPQARSPRHDLEAFAQKVKAGANSAITQYFFNADAYFRFVD
DAKKLGVDIPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTDLCRRLMEAGVPGIHFYTLNAAQATKTICERLGF
>A0A645CCU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MFFDNNIYYNFLYKLREADVRVPVVAGIMPVTNAAQIRRITSMTGTALPQRFRYILDRFG
DNPATMRQAGIAYATEQIVDLFANGVPAVHVYSMNNPAVAQKIQENLSEILK
>A0A1Q6TG27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. CAG:197_41_10|TrEMBL
MKVSELLKSDKVTISVELFPPKKGSQLENYKAIVGRMAELKPSYISCTYGATGGTSDYTV
EIADTINSYGIPAIAHLTCASSTKEKVQSVIKELKDRKIENILALRGDIPEDADFPLPDQ
YHHAIELIGEIKEIGDFCIGGACYPEGHPEAATMEEDLQHLKEKVEAGCDYLTTQMFFDN
NIYYRLYKALAKGINVPVVPGIMPVTNAAQVKRTISLTGNLVPAKFLSIVDRFGSNPEAM
KQAGIAYATEQIIDLIANGVNHIHIYSMNKPDVAGAIMDNLSKIYVRK
>A0A1G8LXF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natribacillus halophilus|TrEMBL
MMEMMDRQSASELIGQMSEPRFELIPTNRIVERTTAALPPYATLTITCSPKKGVDATIET
AVALAPQFARVVPHIGARMIRSEEHLEKMLDKLRAHDIDEIFVVGSDQDQPLGPYRDGLE
LLQSLAARDHGLRRIGIPAYPEGQPKIDNDILTKDLQAKALLADYAVTQMCFDSGQVLSW
LREQREAGLQLPFYLGIPGPVKPDKLLRIAASIGVTDSLRFLRKNLKLSGKLLHGYDASD
LLNAYTPHLNDPDYGIAGFHIYTFNELVTLKKYFERVAM
>X5QGB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSJC280B00|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRVMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDQIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRRPWKREIRRDDQLVADRLDHILHDDLTETQVDMVK
TAH
>E0M3X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. aB|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWTSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMNAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAAA
>A0A2W5H9N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MGYMKIKRALVAGAFSTGVHAKRLPLLALCISSALAAPAIAQSQPAARVQFNIPAQPLDA
ALRRFSEQCGAEIPRWISRRMQAYGDDVDSVRAFGTEVVAKLCQRLIEGGAPGLHFYTLN
LAKPTTSVLKLLQL
>A0A428BLX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1G6S8B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilus telluris|TrEMBL
MTRSVRELLASSRPTWSFEFFPAKTPEGEAQLWTALRQLERLQPSFVSVTYGAGGSTREG
TVAVTERIAAETTMTPLAHLTAVDHSVGELRHVVSRLAAAGVRNLLALRGDPPGADPQAD
WVPHPEGLEYASELVELIRSMGDFSVGVAAFPERHPRSPDFETDVEMFVRKCRAGADFAI
TQMFFRVEDYLRLRDRVSARGCDVPVVAGVMPVTNARQIARIVQLSGQAFPEELAARFAE
LDGDAPEDRAAVRAYGVEVATAMCRRLLDEGVPGIHFITMNRSTATREVFTNLTGAGTSV
PSTLAVS
>A0A4Q7ZQA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Krasilnikovia cinnamomea|TrEMBL
MSLGLPSRLPASPAIGDLIRECAPTFSFEFFPPKTREGERLLWQAIRELESLQPSFVSIT
YGAGGTTRDTTVAVTERVATETTLLPMAHLTAVNHSIAELRNVIGRLAGAGIRNVLAVRG
DPPGDPMGEWVKHPEGVLYAEDLVRLLRESGDFSVGVAAFPYKHPRSPDIDSDTRQFIRK
CRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILPGVMPVTRMATIERSEQLSGAPFP
PALLRRFERIADDETAVRALGIEQCSQMCARLLDEGVPGIHFITLNRSTATREVWQQLAA
RVPA
>A0A4R5W269|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sapientia aquatica|TrEMBL
MSQPNFSIEFFPPKTPEGAEKLRATRTKLAALNPTYFSVTFGAGGTTQQGTLDTVLEMRA
EGLDAAPHLSCVGGSAESIRAILQQYKDNDIRRLVALRGDLPSGYGAGGAFRYANELVEF
IRKETGDWFRIDVAAYPEMHPQARSPQDDLANFARKVAAGADGAITQYFYSADAYFQFVE
QAHKLNIDVPIVAGIMPITNYTQLMRFSEMCGAEIPRWVRLKLASYGDDSASIKAFGLDV
VTQLCEKLLAGGAPGLHFYSMNQAAATTAIWQRLV
>A0A1X0RU91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus microsporus|TrEMBL
MKVIDKIKKAEAENRPFWSFEYFPPKTPQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
ELTTEIVATAQSVYGLETMMHLTCTNMPVQQIDDALEAAKKCGCQNILALRGDPPKGQAN
WESCENGFEHAIDLVRYIRKKYGDYFCIAVAGHPEGHIDNPDKEDDLLRLKEKVDAGADL
VVTQLFFDVDIFIEFYKKARAIGITVPILPGVFPIQNYSGLKRVIAFNDNFVPQKIWDDL
EPIKDDDTAVKEYGINLAVEFIKRFREVGINGFHLYTFNLERSSRLVLERLDLVAPLENI
KPLPWSPSLNTKRAKENVRPIFWKNRTKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
INLRYPVEQCISMWGTPKSVDDIALTFARYCKGEIAGIPWSSQQLDPETDIIRQRLAAIN
LLGYFTINSQPAVNGVKSCHPIYGWGPKNGYVYQKAYLEFFVSPEKLNELIDKISQNPQV
TYYAVNKQGDLRTNTTSDEPNAVTWGVFPGKEIVQPTIVESVAFMAWKDEAFELWNRWAR
IYERDSESAKLILDITDSYYLINIVHNDFQDENGIWRLFDLEIDGEISRKLLQSSVAR
>A0A1G0DX98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium RIFCSPLOWO2_02_58_13|TrEMBL
MNKPLFSFEFYPPHTPEGVEKLAATRLQLAALHPDFFSVTFGAGGSTQERSLEIVQQIKA
ENLEVAPHLSCVGSTRENIRAILQTYKQLGIKRIVALRGDLPSGMASTGEFQYANELVSF
IRAQTGEHFHIEVAAYPEFHPQARSARDDILNFKRKAAAGANSAITQYFYNADGYFHFVD
ECRRLGVTIPIVPGIMPIGRFSQLARFSDTCGAEIPRWLRKTLEGFGDDSESVQAFGLDV
VTELCEKLLAGGAPGLHFYTLNQAAPSLEIWKRLGL
>A0A0R0AQW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAATRLKDYAPDYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQG
>A0A2R3PX67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDHGPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLARPTTSVLKLLQG
>A0A645AJM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MKIIDIIEEKKPSLSFEVFPPKNSDTYESIINATEKIADLVPSYMSVTYGAGGGTSAYTV
SIAEDIQNKFNVPALAHLSCINSSYESVHNQLDSLKEAGIENILALRGDIAPGESVKEDW
KYRYASQLVQEISEYGGFCIGGACYPEGHTESRTQAEDIEHLKKKVDAGCEFLTTQMFFD
NNIYYNFLYKVREAGIHVPVVAGIMPVTNVNQIKRITTLSGTVLPQRFRYILDRFGDNPA
AMKQAGIAYATEQIVDLFANGIPAVHVYSMNNASVAQKIQENLSEIIK
>A0A2P2C9L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|metagenome|TrEMBL
MRNKVANRNILLDLLAHARYEVLPTATTEDKILAHLPKDRVITVTASPAKGLGITFDLAE
RLGSAGYPVVPHIAARMVSGRSELAEICDRLTSAGISRIFVPGGDADPAGDYVDALGLLE
DLKELGSPFEHVGITGYPESHPKIHDDLTVQAMWDKRRYATHVVSNLTFDPAVIADWLGR
LRARGVTMPLLLGMPGPIDRAKLLGMAGKIGVGESTKFLSKNKGLFARLAAPGGFTGERF
LEQCAPALGKPGALVEGLHVFTFNQIEATENWRTSMIDRLSRE
>A0A7K1SID2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirosoma arboris|TrEMBL
MTKITDHIKAANGKPIFSIEVIPPIKGDNLKNLLDNIEPLMEFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHRFGVDPVPHVLCGGFSREETEDFLIDLHYLGID
NALVLRGDPAKPFTTFKAKENGYMYASELVEQVANMNRGIYLHEEDTALAPSNFCIGVAA
YPEKHFEAIDHDIDFHYLKQKIDKGADYIVTQMFFDNQKFLSFADRCRQEGITVPIIPGL
KPLSTRKQLQILPKLFHLELPEDLVKAVEACENDQQARQVGVEWCIQQCRELTAAGAPVL
HFYTMGKADNVMKIAREVF
>A0A1E4IN54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax sp. SCN 71-131|TrEMBL
MRALRNWSVRHASALWRLYRHLAARAPALHGVVRSVGAARVERLLAPVERQLKGAFFDCR
MCGDCRLSSTGMACPMGCGKQMRNGPCGGVRADGGCEVHPEMRCVWLDATEGDLRIDPKH
TPTWTQRVPALDWRLQGRSTWLQAITVSRRAEPEPGPGSPASAAPAAAAQEAVSALERAC
RAWHAQRRFIVTVEIAPPDSPDPQPLIERARRFHGLVDAINITDGAGANCHMSSVAAASV
LTAAGIEPVCQVGCRDRNRIAVQGDVLGAAALGVRNVLCLTGDDVSQGDHPQAKPVFDLD
AVNLLHILRGMRDEARYASGRPLEQAPRLFLGATANPFVAPFAERVANLERKIDAGARFI
QTQFCFDLGLLEDFMRAVRARGLHERAAVIVGVGTLPSAKALRWMADHVPGVRVPEAVTE
RIAAAADPRAEGVRVAVETIHALRRIEGVAGVHLMGHRNEATLARIIVDAGLRTPRVETE
IA
>A0A292Z6G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. N23|TrEMBL
MSIRDLLGTSVLVGDGAMGTMLHAAGNSLDQALPALTLTEPGLVRTIHDSYVGAGVDLVQ
TNTFGASRLRLAEYGAADDVARINAEATRLAREAAARADRQVFVAGSVAPAVSVHQRRRV
VPSARRAAVREQVEVLVGTGVDVVMLETFGHLDELVEASEVALEIAQRAGDVPVIAQATF
GTDHHTLSGHTPHELVTALAGLPLAALGVNCTLGPQGCLAVLRELALHTSVPLTVQPNAG
LPRRIAPARFEYDIDADYFVRYTRQLLDAGAALVGGCCGTTPGQLAAAAAAVAEYRAQRV
TTVVEPAPAGPVVVTEPGLFASTGRVVGVELTPPTSGGVDETVALAADLREAGAGLVCVP
ATSGPRAQVNSVDLALHLHNRLGVTTLASVTTWDRTIMALQADLLGAHALGVRGVLCETG
TPPLVGDYPHVDGIWDVDSLGLIELLAGLNEGTDYHGLRLGTKTSFDIGARVNPGSRDPG
RAAVEALDKIAAGAQFLITRPVYEPAGLARVVDAVDGRVPLLVAIRPLTGFDEADYLAHE
VPDVTIPDATLAALADAGPDAAAAGVDLAVALAEQVRPMTRGVVVTGGSDVAGTVRRLLL
>A0A5K8A2R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosarcina ovata subsp. sediminis|TrEMBL
MLRILKEDLANPHNFVVTLELVPARESFGRSTETLLGIARDAFADGRVSAVSITDNPGGN
PSLSPDVLGYEIFKLGLDVIVHFTCRDTNRMGMESRTLQLARMGMKNVLALTGDYSGKGY
GGRGTPVFDLDSVLLTGMLKSLSEKMAASGDPDPFFTGCAVSPFKSLKGSAHETEKIVR
>A0A3S3RV16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electrothrix communis|TrEMBL
MPEQVGHRMIYPAQPGYMASRAREMIRNGVHLIGGCCGTAPSHIQEFRSALKIKPVRVRI
QDVKIKEEVQEDIIPEPQNGGFLESLQPGRLPIIVELDPPTHLDAEPVLEGAERLAEAGV
DAISLGENPLAILRAGNLGVASLIRQRTGVQTIIHQTGRDLNALGIQSRMMEAHLLGIEA
VLAVSGDSAAGTDQPG
>A0A3S0J6S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas nitroreducens|TrEMBL
MSAHEHPLGISFEFFPPNTDAGRDKLMRTRDALARRQPRFFSVTYGAGGSTQHRTLNTVQ
AVRESGITTAPHLSCIGSEKAVLRDLLAQYREQGIDSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAPSLDRDVENFARKMKAGANLAITQYFFTADAYF
HFVERARVLGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSQAIADF
GEDVISRLCQRLLDGGAPGLHFYTLNQAEPTLKVLDNIRA
>A0A2D3UNP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramularia collo-cygni|TrEMBL
MHITKKLASAHAKGTATYSFEYFPPKTAQGVQNLYDRMDQMHGLGPAFIDITWGAGGRHS
SLTCEMVKVAQSVYGLETCMHLTCTDMELSKVDDALKEAYHSGCTNILALRGDPPREQEK
WVETQGGFRYARDLIKYIRKTYGNHFDIGIAGYPEGPDETTTADEHIVYLKEKVDAGGTF
IVAQMCYDAELFIQWVKDCRAAGIPESVPIIPGIMPISTHAAFLRRANWSGARIPPAXNE
ALDPIKNDDSAVREVGRDLMVEFCQKLLAAGIMHLHFYTMNLAGAVRMVLERLDLTPSAE
SPDPEIKPLPWRQSLGLNRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
GLDEYGVGLKGTNESNRKLWGEPKNVNDISKLFVKYMTGKVETLPWSEAPINEEANVLVK
DLTDLNNRGLLTINSQPAVDGAKSSHPVYGWGPRNGYVYQKQYLEVLVCPELFPTVIQRM
EADPDITYYAVNNSGDLKSNAPTDGGPNAVTWGVFPGKEIVQPTIVXTVSFLAWRDEFXH
LGLEWSKCYDEGSESRALITEITKSWYLVNIVHNDFRNQSGIFPIFEGLTVPGVDATPIT
NGHTNGHTNGHTEAGAKENGGPKPETNGVPDGNNVVNGADKVAAST
>A0A413KE72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium pseudocatenulatum|TrEMBL
MHSPMFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVS
EYGIPSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFEHASDLAI
YIRQQRPDMKIYGACYPEKHPQSATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KARAAGIDVPIEAGIMPVMNAKSVLNMSNKCQSKVPEKLGIMLDKWGGDKALLKEAGIAY
ASEQICELVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A076MQF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis methanolica 239|TrEMBL
MPFASTERKVLEHVPVTVPLTVTVTEAKGLDTTLDLTERLLGHGYRATPHLAARLFRDDR
HVADVASRLREAGADSVFVVGGDAPAPAGPYPDAYALLQALERAGHSFRAIGIGGYPEGH
GVIPQEAVDLALKQKAPLATRILTQICFTAATTHAWAERIAASGIDLPIHVGIPGPVNRQ
KLIRISAGLGLGQSARFLRKQQSLLWRFLLPGAYQPGKLARRLASRPAGNIRGLHIFTFN
ELAGTERWRQGLLATLGVEEGRP
>A0A6H9I2U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobi bacterium|TrEMBL
MKVTEHLENSTRPLISFEIIPLPRGGDIRQVFEIIDELIKFEPPFIDVTSHSAEVHYEET
ASGIRKKVKRKKPGTIGISVAIKNKYNIDTVPHLLCTGFTKEETEDALIELNYLGIENVL
AIRGDDNGYIKPLTDGRTSNRYAIELVDQISKMNQGIYLDTELLNASPTNFCIGVGGYPE
KHFESPNLSFDVEYAKKKVEAGAEYIVTQMFFDNKYYFDYVRRCRDAGITVPIIPGLKIL
FTQKHLTNIPKNFFVNIPEELSGEILKSKSEHAMEIGINWTLKQCEELLNNNVSSIHFYI
MHNIKPVKKLMDKLKL
>A0A7J4VGB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobi bacterium|TrEMBL
MKVTEVLANAKKPLISFEIIPPKRGGDIGSLLNTIENISQYKPPFIDITSHAAEVIYEET
PKGIRKKVIRKRPGTLGICALIQNKYGIEAVPHILCKNFTKEETEDFLIELGYLGVNNVL
AIQGDDKGFEKEVSEGRTINKYALDLVKQVTDMNKGIYLEEELLDAKPSNFCIGVSGYPE
KHYEAPNLKTDMYFTKQKIEAGADYIVTQMFFENKAFFNYKNVAVEMGINAPILPGLKII
TSKAHLTGIPKNFYINIPEELTGEILEAKPEHVMEIGVNWAVKQAEELINSGVPCLHFYI
MQNPKPVNMLMQKLKI
>A0A3M1LX31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobi bacterium|TrEMBL
LSQYSLAAIGASGTVGPQRMRGVISAMRSGSSLPLVALPDTGIPTMVGSRAYYSTDPDYI
ARTLRELAESGARILGTDRGTTIAHTSATSQSLAGITHAAPPPAPIQREAHLSPRPTVPP
PSRFAQALQERFTITVELDIPRGLDMASVLEGARYLGKHGVDAVNISDGARARLRVNSLM
LSASVQQQTGIECIAHLACRDRNMVALQSDLLGAALLGVQNILAVSGDPTHIGDYPRATT
VGDLDSIGLIRALRMMNSGRDLAGNPLGSTTNFCIACACNPSAEDIERELDRLAQKVAEG
AEAIFTQPMFDLERWLQFLDRAGSLPARFIVGILPLRSVRHAEFLHYEVPGMTIPAWVRK
RIAESPNPAEEGISIAAEFLAAVKEHCHGVYLMPPFKKYDVALSVLERAGIATPSR
>A0A7V5VTW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobi bacterium|TrEMBL
MKLPFAERLRQGVLVTDGSIEAELQRRGLWEQPPELYVLEQPAVVEDIHRCFVEAGADIV
QTNTLRANRIALERYGLADKVYELNRTAVWLARCAALHRAYAAGVVGPTGKLLGPLGPIE
PEAARQAFIEQIVALVDGGAELLFLKGFVEVRELELAIEAAQMVNPRLPIVALKAFAEDG
SVLASSFPSQVVQRISRFLVAALGAAGTVGPQRMLSIARRIVAVASVPVCAIPDVGVPQI
KGDVRSYNPEPDYLARVARELVELGVRIVGADGGATVECVRAIVQAVQQAFPGRAVEKKL
EPEPTGDTEPVFAEPPPPTPFAQKLGRKFVVTVEMDVPRGVGMDSVIEGARYLQRCGIDA
INISDGARARLRISPIALAHLVQSQTGMECIAHIACRDRNLVALQSELLGAYALGVRNIL
AVTGDPPHIGDYPFAAAVFDVDSIGLIRILRSFNEGRDASDNFLGQKMNFCIACACNPAA
ENWREERARLERKVAEGAQVVFTQPVFDLKLWERFRQATEQLPVAVVAGILPLRNVRHAE
FLHYEVPGITIPVWVRQRMAQADTPEAAIAEGIAIAVELVQAVRHTADGIYLMPPFRRYD
IAVEILRRLELIPEQPALVP
>A0A1G8C2L0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. YR213|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVNRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEMHPQARSPQDDLNAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>K2AEC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MLALTQCTTLCSRLLEGGVEDLHFYTLNRPELTRDVVRALGIAPEIAPEVVLEKVA
>A0A3E3IBT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eisenbergiella massiliensis|TrEMBL
MKISELYQAKQNQGNPSKKTLSFEIFPPKKDSELKNIDKTLAVLCELNPDYISVTFGAGG
GANRNRTIELAKRIKQEYHVEPVVHLTCLHYDKAEIDEFARVLANAGLQNVLALRGDKNP
DMREKESFCHASDLIAYLKGKWDFCFLGACYPECHPESEDKVGEIRHLKAKVNAGAEVLL
SQLCFDNHAFFRFQEACRIADIQAPIIPGIMPVINAAQIKRMITMCGATFPVQFQKIIQK
YESNKEALFDAGMSYALSQIIDLLVSDVEGIHLYTMNNPLVARRICEGIRNIV
>A0A1M5L8F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jatrophihabitans endophyticus|TrEMBL
MPRTVREALAESGPTFSFEFFPPKSEDEEVLLWKTIRELEPLRPSYVSVTYGAGGSTREH
TIEITEQIATDTTLMPVAHLTAVGHSVAELRGIAGNLAAAGVINVLALRGDPPGDPEGEW
VKHPEGLEYAAELVTLLRAHGDFCVGAAAFPNGHPRSPSVDSDTEQLVAKFRAGAEYAVT
NMFFVVDDYLRLRDRVAATGCDAPIIAGLMPITNFGLIRRSEQLTGAPFPEQLGKRFAAV
SHDPKSVRAMGIYETSKLAERLLEEGVPGIHFYTMNRSKATREVWANLALGARV
>A0A1W9UMC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_35.2|TrEMBL
MLMKNILDQNTTSLSFEFFPPKTDLGWQRLFDNIGQLAPLNPSSVSVTYGAGGTTRSQTN
ELVLRIHSETGITVVPHQTCVAATKDDVHAILSHYQQSGIENVLALRGDKPQDDENLCVA
ENGFHYAADLVAYIRQHFPTMSIGVAGFPEGHPEMANRLLEIDYLKQKVDAGADYIVTQL
FFDNRDFYDFCQRCQLAGITVPIIAGIMPLRNRQGMARMAELAAGARFPAELLRRVYAAA
NEDEVEQIGIDWATEQARDLIANKVRGIHFYTLNSATATDSIFERLGLK
>A0A3B9SM67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
MKVTDHLTAANGKTLFSFEILPPLKGTRIDELFGTIERLMAFGPKFIDVTSHREEFIYKK
RENGLLEKVHTRKRPGTVGICAAIQNQFKVDTVPHVICGGFSREETEYALIDLHYLGIDN
VLVLRGDALKAEGAFKPEPHGHTYAIDLLKQVSDLNKGHYLHDEVENSNPSNFCIGVAGY
PEKHFEAPSLNTDIKYLKAKVDAGAEYVVTQMFFDNQHYFDFVAKCRKANIHVPIIPGLK
PIATASQLTTIPRNFHLNLPDDLVEEVEAAKTPAAVKEVGIQWCITQSKELMAKGAPVLH
YYTMGKADATEKIASALF
>A0A074W0M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snodgrassella alvi SCGC AB-598-J21|TrEMBL
MSFTQLSFEFFPPRTEEGRRKLAITRKQLSQYQPEYFSCTYGAGGTTRAGTLQTITDIMN
DGVAAAPHLACIGASREEMISLLQTYKDMGIRHIVALRGDVPSGVGFGHQGLRYANELVA
LIRQEFGDWFHIEIAAYPEFHPQSRSAEDDINHFVRKCQAGADSAITQYFFNADSYFWFV
DEVQGRGIDIPIIPGIMPIASFSKLARFSETCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCDHLLQQGAPSLHFYTLNQAGLVSTICQRLGY
>A0A6H5I932|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichogramma brassicae|TrEMBL
MGPITKRRTMTVLMWHLNIILNCAMKLSCACERVMVKIYWQRRLASNPTNKNMKVINRIE
ATTNPNQKLGPMDEFIERRKKRPSGEQPNSSSRNSNKSNNKRKSGKSAKKKSRNAWYEND
SSDEYVTKLKADDIGVGISKSQRTCSKGKQNLFAEMSSTSSESEPEQPEDNLDDQRTKTK
KSTTSNTTKKKDRSKTSKKTILPENQTMAKNWEDGDDVNKTASSALDLDSCKKSESELSD
HPLVIDESHREINETERRTNSDAETEERAVELDDWYREDSSIPDSENENLTEEKSDKLIS
ENKNINSEQYISVEDALKILDQQQEESKKPKNKRSSPKDNKKKMKKSPVLPEKQSNSEKG
DLENLPLHVFLNRKVQESKKRKEVKNQKREQNLSEEEQAHEEQSPPEIPPARRQRKCAVG
KQGLLAEISSSDDESDREYHRSHGKARLRESREKRKERSIEKKHELMFAKEQKAIEESIM
RELEEKRLSAASEASGTDDYKEDKKEQAQAKDSAKSSPAKKTPQPKPKLEDTDDSLKQAS
STQKKRKAASNKSSKSKSTKEPKTSSIKETQSDTEFKEEDDELKAKRSWNNVDVDVGIAI
GRRKRVATRQLYYWSTTSSSDDEKAEATSTAVSVAPDVPAPGVGPEDECPEQHGWIVGHS
HKQMITMLAMEKQMKEKRRRSEDEDQALNLSTQSATTSLMVPGADAATASSFSPCGGNVM
SANKSVKAKKHRSNTSSQEGDFIYASDLVSFVRDRFGQRFSICVAGYPEMHQSSLSKELD
LFYLKNKVHADFVLYH
>A0A8J6TBN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfobia pelagia|TrEMBL
MKSGSRLERVLNSGEFAVTGELGPPKNSDPEVVRKKARILKGHVDAVNITDCQTAIVRMS
SISAGLLALQEGVEPVIQMTCRDRNRIMMQSDILGAAALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMARDMRDKNMFQCGEEIKPEGPKMFFGCAANPFANPFEYRAPRLAKK
VANGADFVQTQLIYNMDKFTRFMEMCRDLGITDKTYILAGVTPPKSVGMARYMQNFVPGI
EVTKDIIKRMQGAKDKQEEGINIAVDIINQCREIKGVAGVHVMAIEWEEAVPEIIKRANL
DSRPVFEDEPVKAAKVLDETIVVAGSATAVSADSDKVLADAKTEAEKIIAAAKAEAQKLS
TGTAPATVVESAIEYDDAGEHEMNENERQMALKSIQHGLDALKKAFNLTEDQFEALSSFA
GAEAVLKKEPSAKPAVTPAPAAAPAVPAAPAAPPVKEDDSAKKAAEAKAAEEAKKSAEAK
AAAEATAADDAKKAELAKAADVKAADDAQKAAAEAKASEEKAAAEAQKAEAAAKPAAAPS
GDLAVADLAKEKTLLADRATKVPADSYTVKYSGSIKETVLGNGDKTITVGGAQSMPFHLF
EGANPHNPLIAMDVLDSRPQEWPESLSRHFADVLDNPVAWAQKCINEYNADAICISLVST
DPNGMNRSSAEAAKVAAEVINSIDVPTIVWGCGNGEKDTETLREVTSLIGNKKVCLAPLE
DSNYRSLGATAMAFQYPIVAASPIDVNLAKQLNILLENLGVNLETVMMDPSVGALGYGIE
YTYSVMERIRLAALTQQDEKLQVPIICNLGREVWKAKETRLPSDNVIGDQERRGVMMEAI
TATCMLVAGGELLIMRHPKAINLTKSLINSLMS
>D8LCN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectocarpus siliculosus|TrEMBL
MSSEPDTKIIDLIQASAKEALTEGGAGFQSLEFFPPRTDTGVMNLMDRLGRMKATKPLFV
DFTWGAGGSTADLTLDLTTRTKKEHGLVPNMHLTCTNMPVDKIDHALAQCKEHGIRNIVA
LRGDPPTGSDTWEAAEGGFTCALDLVKYIRKNHGDYFGISVAGYPEGHPNRIKEVPGGVE
SLSEAEKGRCKISQDAEGKEVVTVCSDADFEIEMNYIKEKVDAGADFIITQMFFDPAVYA
SYIKACRDRGIEVPVVPGLMCINAYGGFKKMTGFCLTRVPPELMAKMEEMKEDEKAVKAF
GVDYGEKMCNALLAAGAPGLHFYTLNLEKVTVGILDRLNLLADYKMAEREEDTAQMIGMI
KSSKKSPEESGPENGAGVTPAAPSSLVQTRDEERVLTPA
>A0A2D5YQM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovorax sp|TrEMBL
MKVTEHIDKASGPLFSFEIVPPPRGKTIKAATDVVEQLLPHNPAWIDVTAHPAGAYYNEN
PDGSVERKVYKKRPGTIGICGVIQNRFKIDTVTHLLTQGFTKEETEDALIELNYLGIHNV
LALRGDNLNYNKKYAKDRSRNFYASDLVKQINLLRKGEYLDDINNSLPLDFCMGVAGYPE
KHFEAPNLKTDIHYLKEKVDAGADYIVTQMFFNNQAYFDFVDSCRAAGITCPIVPGLKVI
KNTKQLTTVPRHFYVDFPDEFVSQMLEDPDHAEEIGINWAKKQTEELMAANVPSIHFYVM
NDAKSVSQVVKKFF
>A0A559MCI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnellula willkommii|TrEMBL
MEKITDKIAALPPGTSYFSLEFFPPKTAMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
AEKSLELAELCQRELGLTTCLHLTCTNMSKELVDKALEDAKALGVRNILALRGDPPRSSE
YGTETAVVEEFEWAIDLVRYIRKVYGDYFCIGVAAYPEGHADESHPEGQSVEHDLPYLVE
KIKAGADFIMTQLFFDVEAYDAFERRLRENESGVFKTIPIIPGMMPIQSYQMIKRTTKLS
HAKMPPSITERLDVVRGDDEMVKKVGVDILSEIITHIKDEPPGPGPRGFHFYTLNLEKAV
SFILERTNLIPASPPDPDSEYAIIDLPLQPIDANGSEASQKKPSRRQSSVGSDPYNRIII
TASSTSHPSHEATASEAGQPAQAVNTRANTLAISEGEGTLGREATWDDYPNGRWGDARSP
AYGEIDGYGVSLHMSTNQAVKLWGYPTSVSDITALFIKHIEGSIAAIPWSEEGLNEETST
IKSQLLALNQKGWWTVASQPAVNGVRSSDAVFGWGPKNGFCFQKAFVELFIPSSAFPSLL
QKLEDSEEVSYYASNAKGEFKSSGNGGANAVTWGAFPGKEIVTPTIIEEVSFRAWAEEAF
GIWGEWGRVYGRGREESRAVVERCMGDVWLVNVIHHGFVEKDGLWELLLS
>A0A1V0DEQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermaceae bacterium RA|TrEMBL
MHVTEILDRATEPLISYEIIPPRRGGTVEQVLAVVEELMPFEPPFIDVTSHSAEAIYEEQ
PDGTWKRRVMRKRPGTLGLCAAIKGRFGVETVPHLLCNGFTREETEDALIELNYLGIHNV
LALRGDDHGFQKPVSPDRSRNRYAAELVQQIAAMNRGEFLDDLVDAAPTNFCIGVAGYPE
KHFEAPNLAWDVLNLKRKVDAGAHFITTQMFFDNRRYFEFVERCRDVGIDVPILPGLKIL
TSKRQLQLLPSRFFIDIPEPLAAEVEAARPEHVVDIGVEWAIRQCEELMAANVPSVHFYI
MQTASVVKQVVTALRKMA
>A0A2E5JMB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovorax sp|TrEMBL
MKVIEHLERAKNPLFSYEIVPPPRGRTVQDVVDVVKKLAPFDPPWIDVTAHSAGAYYSEK
SDGSIERKVFKKRPGTIGICGIIQNRFKIDTVVHLLCHGFTKEETEDALIELGYLGVENV
LALRGDGLNYDKKISTGRSLNKYASELVEQVVALRSGQYTSDLSEAQPIDFCVGVAGYPE
KHFEAPNLAIDIQNLKKKVDAGADYVTTQMFYNNDHFFHFVEECRKAGIKVPIIPGLKII
KSLSQLRTIPRNFYINFPDDFVAEMMENPDHAKEIGLAHTCKQVEGLLNKGVPGVHFYIM
NDADRVIDVVKKFR
>A0A3N0VKP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stagnimonas aquatica|TrEMBL
MSHAHELHFSFELFPPRTPVGWTNLPRLIGELAAVKPAFFSVTYGAGGSDQNGTYDTLIQ
VIKQTGIEAAPHLTCIGSTRTGIAALLDQYRAAGVRRIVALRGDLPATAISNAAPGEFRY
ANELVSFIRETHGDHFQLEVAAYPEVHPQAASPDADFAAYLRKVEAGASGAVTQYFYNAD
AYFDFVERGEKAGLRIPVVPGIMPIVNYGQLQRFSDACGAEIPRWLRLRLESYGEDKASL
QTFGLDVVTRLAETLLKGGAPGLHFYTLNQAEPTLKLWRNLGLPAA
>A0A1V3NW57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. C05|TrEMBL
MPAISFEFFPPKTDEQRTQLDRAAQVLKAYQPEYASVTFGAGGSTLSYTGDTVARLHVQH
GLNVAPHLSCVGGTRAELATLLDEYRTAGYRRIVALRGDMPSGMATAGDFRYAAELVGFI
REHCGDHFHIEVAAYPETHPQADDALRDLQHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VRRLGVDVPIVPGIMPIANYTQLKRFSDMCGAEIPRWIAKRMQAHGDDADSIRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRARATQSVLQQLS
>A0A3N9TB54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio viridaestus|TrEMBL
MGYTHASHIDALNQNIAELSDDINVSFEFFPPSSPKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDATRDELITIAEDYWKNGIESIVALRGD
IPAGGGKPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVSNFKQASKFAAINNVKVPSWMTKQFE
GLDDDPTTRQLVGASQAIDMVRILCREGVKDFHFYTLNRAEMTYALCHTLGVRPQV
>A0A838NUX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadaceae bacterium|TrEMBL
MNPDSRRKRRPRLSKNPLIDRLLDPMQVIVCDGAMGTMLYNKGVFINQCYDELSVRAPDL
VREVHRAYAKAGAEVLETNSFGANRYKLAQYGLDKQVREINLAAAKLAKEVAEDEILVAG
AVGPLGVRLEPLGPTSLAEARAAFAEQLAALHEGGADVFMLETFSDLHEIEQAILAARDV
APDVPVMAQMTIGADCLTPFGVEVEDLARALDAYGADVIGLNCSVGPQTILDAIEKMMHV
TRRKLSAQPNAGMPRDVGGRSMYMASPEYMGTYAHHLVQAGAKVVGGCCGTTPEHIAAIV
EGVRPLSPRQPRVPMKERRQSHLEAPKEDKGVEPMPFGERSKFAGKISRGEFVTSVEIVP
PRGVDASKMLVDTAALRKAGVDAVNVPDGPRAQSRMGALLTSLLIEQQVGIETVTHYCCR
DRNLLGMLSDLLGASAVGLRNMLIITGDPPKMGPYPSATGVFDIDAIGLTNLLSNLNRGL
DPGGNSIGRPTTFSIGVGVNPAAIDPKHELKRFEWKVDAGAEYAITQPVFDVEQLERFLG
TIDHVRIPIIAGIWPLVSLRNAEFLANEVPGVVVPKSIIDRMSAASAESKEAGVAEGIAI
AREMLERVRPLVQGVQVSAPFGKVDLALQVFRDHLSPTTTAA
>A0A0S2T637|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium glutamicum|TrEMBL
MSLTNIPASSQWAISDVLKRPSPGRVPFSVEFMPPRDDAAEERLYRAAEVFHDLGASFVS
VTYGAGGSTRERTSRIARRLAKQPLTTLVHLTLVNHTREEMKAILREYLELGLTNLLALR
GDPPGDPLGDWVSTDGGLNYASELIDLIKSTPEFREFDLGIASFPEGHFRAKTLEEDTKY
TLAKLRGGAEYSITQMFFDVEDYLRLRDRLVAADPIHGAKPIIPGIMPITSLRSVRRQVE
LSGAQLPSQLEESLVRAANGNEEANKDEIRKVGIEYSTNMAERLIAEGAEDLHFMTLNFT
RATQEVLYNLGMAPAWGAEHGQDAVR
>A0A3T3EVC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella muenchen|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7Y3FXB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MTLKNKFDVGDFVILAEVDPPKGVDISSLTDHAMRVKGKVDAFVVPEMSNAVMRMSSLGA
AMILQSRGVETVMQLNCRDRNRIALQADLLAGFGCGITNVMAVTGEDPSFGDHHQARSVY
DIDLLELLQAIKNLEQGKDMAGIELKGSPDFLAGSTTNAGAEGISPELELEDLTKKIEAG
AKFLITPPLFDLKSIQPFLKKLDQTKVKIIPTVLLLKSLGMARYMARNMKHIHIPDELIS
RIQKAPDKVRECIRIASDMITALKQENLSGVMISTIGWEDKLPEILEKV
>A0A432TWT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thioglobus sp|TrEMBL
MKTSFEFFPPRTDKGKQSLAQVRQELSKIHPEYFSVTFGAGGTTQDATLETVLDIQANDG
ISAAPHLSCIDSKKSKIIELLDQYKAADINRLVALRGDIPSGVRDIGDFHYANELVEFIK
SEYNDHFHIEVAAYPEVHPQAKNIQTDLQHFANKVKAGADAAITQYFYNADAYFRFKDEV
EKMGVDIPITPGIMPITNHTQLLRFSNMCGAEIPKWILERLKLYENDLESLTLFGTEVVS
NLCRTLKDQGVDSFHFYSMNRTEPSLAIAKSLI
>A0A7C7J124|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEKIANYKAQGKTFYSFEFFPPKTDFG
>A0A1X1PCI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia puraquae|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLMPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVM
>A0A420V5M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces xinghaiensis|TrEMBL
MFSFEFFPPKTARGEQTLWRAVRRIEPLAPDFVSVTYGAGGSSRERTVELTRRIAAETTL
RPVAHLTAVGHSVAELRHIIGQYADAGIRDVLVLRGDPPGDPGGPWTPHPDGFTHAYQLV
ELVRSLGDFTIGVAAFPEKHPRSPDWESDIRHFVAKCRAGADYAITQMFFDAEDYLRLRD
RLSAAGCDVPIIPEIMPATDVRQIRRFAELSGAAFPEDLAHRLEAVCDDPAAGHRIGVEH
ATAMAGRLLAEGAPGLHYITLNKSTAALDIHRTVLGSRSVHVS
>A0A3R7I4T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces xinghaiensis|TrEMBL
MPVRTTLREILGSGRLSFSHEFFPPRTEAGTRTLWNAIRRIEPLAPTFVSVTYGAGGSSR
DRTVEVTKRIATDTTLRPVAHLTAVGHSVAELRRIIGQYADAGVRDVLALRGDPPGDPNA
PWVPHPEGLTHAHELVSLVRGSGGFGVGVAAFPERHPRSPDWDSEIRHFVRKCRAGADYA
ITQMFFRVEDYLRLRDRVAAAGCCTPVIPGIMPATDVRQIARFAELSHATFPEGLARRLE
AARGNPAEGHRIGVEYATAMAGRLLAEGAPGLHYITLNRSTATLEIHRNILGTPAPGSAR
QVLAAPL
>A0A346BG62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia caffeinilytica|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLASLKPKFVSVTFGAGGSTQQGTLNTVVEMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWVEVAGYPEYHPQSRSPRHDLENFANKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCGRLIDAKVPGLHFYTLNGAAATKAICERLGA
>A0A0N4TCQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brugia pahangi|TrEMBL
MALSVFSKFSGNISSETSSSSVAAGCLDYCGMDTMLHITCCPYTKEQSIRHLEQSKALGL
KNILALRGDLPRQDENPVLYKYRALDLIRWIKEEYNDYFTIACAGYPAGHPEAPSYRADL
LYLKAKVDAGADFIISQIIFDGEVFKNFLRDCREIGITVPIIPGILPIQSYESIRRVAEL
SQLVIPDSILTSLEPIKNDDDAVRNFGIWHAVTLCRTLFSNGSATSVHLFTLNREASSR
>A0A6B3KNF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas euvesicatoria|TrEMBL
MISTDTPNFASTVTEAYSLEVSAKDIGALTNAAPRILPGCAMFIPYLPGQNQAVRLAAAQ
MVRSLGFEPVPHLSARRIGSLGELQACIARLVDEAGVTRCLVIAGDPSTPKGPFPDSVSL
IETGVFERSGIRTIAVAGHPEGHPILRTTEQWEVLERKCRSIQERGMAPLIVTQFGFDAD
IVVTWLEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFG
>A0A096FN24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas testosteroni|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPEFCSVTYGAGGSTQAGTFTMVRDIQNE
GVGAASHFSCIGATHEKVRAELNELKAMGVKRIVALRGDLPSGYGLGGEFQYASDLVAFV
RQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VKALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A318P3E0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia plymuthica|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLDAAPHLTCIDASPAQLREIATDYWNNGIRHIVALRGD
LPPGGGKPDMYATDLVRLLKEVGDFDISVAAYPEVHPEAKSPQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAA
>F0UPZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces capsulatus (strain H88)|TrEMBL
MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTWAVDLVKYIRRTHGDYFCIGVAAYPEGHSDESYPEVQDPVKDLPYL
IEKTRAGADFIMTQLTYDLGAYKRFEEMLRNHESGVFETIPIITGLMPIQSYHILTRTTK
LSHARVPPDIMARVEAVKSDDEEVKRIGVDILCEIVNGLKQVSYPGPRGFHFYTLNLEKA
VALTVEKCNLIPPLSPLPSDSETYMDTAVFMAQGKQNGISLLSKRRASSMNSQPHNRLIV
DRPSDAGGSSQASTTHETPALGAGMPALNPPPRTTTLQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVNAAVARRLWGYPTTKQDINNIFQRHVSGELHLVPWSEGGA
QDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAF
VEFFCPAHDFESILKPIFESHSHDEFAWFATNVAGDFMSSSPATDATTEDSSGPVDVFLD
SNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIFPRGSPTER
LLDQLKNDVWLICCVGQKYGAGCASLEAAEAEGKLLWKLLGGTGTGPDSVNNH
>A0A0B0NE02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium arboreum|TrEMBL
MKVIDKIQSLSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DVLVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A2E4W3C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MPPADTSSIQLIRDFYARRLQGDRPVISFEFFTPKTDEGDKKLMEVTLPELLQLAPDYVS
VTYGAGGSTRAKTLTLVEAIQRRYGLTAMAHLTCVGHMEDDIAEILSEAKTLGIRNILAL
RGDPPAGQTEFVKPKGGFEYSYQLIEFIRRHGDFCIGTAGFPEGHMACREGKLADWGYLK
QKIDMGAEFVLTQLFFDNSEFFEFRDHVVQRLGVTVPICPGVLPILSAKQVVRFTKLCGA
RIPAPVRARLELLTDDEEGATEFGIEHATKQCEELVREGVPGLHLYCLNKVRSARAILKN
LGLAGR
>A0A5M3YRB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus terreus|TrEMBL
MHISEKLAQNEAAGRPGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDAALQSAYKAGCTNILALRGDPPREKEK
WEATDGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSSF
IVTQMFYDTDNFINWVKKCRAKGINVPIIPGIMPIQTYAAFMRRANWTKIRIPPEWLEAL
EPVKNDDAAVKEIGKGLIADMCRRLLAAGINHLHFYTMNLAQSTQLVLEELNLTPSEETP
LQKPLPWRPSLGLNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIKLWGEPKSIRDLAHIFVKFMQGELARLPWSDTPISGEANAIKDKLIE
LNKRGLFTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLVPPYLLDELIARIEKNE
DLTYHAVSKTGELRTNTRDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHEAGSPSRKLIQGVMDNWYLVNIVNNDFHNSFNLFELFDGLDVKDIDTEIAPEPKPQE
NGTLNEATNGAALEASVKN
>A0A098Q1M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis pv. vasculorum|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIDCSRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIVPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVCAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A0E4A860|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus erythropolis|TrEMBL
MTFDPVRGRSSEGWATRTPSIVDRIASSTGSRIPFSVEFSPPRDADAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSTEELRAMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPEGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
YDTKYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVSAYDAEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGPDENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTPDTSVGTAQAV
>A0A4S9KMH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MPSDRIVDKIAALPEDSTYFSLEFFPPKTQQGFANLHARLSRMAHSLRPLFVNVTWGAGG
STSTKSLALADMTQRQLGLTTCLHLTCTNMSRKLIDGALEQAKALGIRNILALRGDPPRS
DEYRSNELENEEEDDSNKEFTWAVDLVRYIRKEYGQYFCIGVAAYPEGHSDQSHPEHQHA
TYDLPFLVEKVEAGADFLMTQLFYDVHAYQDYEKLLRQHESGAFKTIPIIPGLMPIQSYQ
ILKRTTKLSHANLPSELSNRLEPIKNDDEAVKRAGVDILSEMVETLKKNSYSGPKGFHFY
TLNLEKAVAHIVERCKLIGAVNNVAVEDDDTPVANGNGDKKAKARRRSSIANSAPQNRVV
IDKTSRSASSGSATFEAFDDEAGVPGEDPPSRKDALAISEGEGALGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHVSIPSALKLWGYPVDTKDITSIFARHVRGELDAIPWSEEGLN
PETETIREELAGLISKGWWTVASQPGVNGFRSDHEIFGWGPPNGFVFQKPFVEFFCSHED
WTRLRTKLDKDDQVTYFACNGKGDFQAADEESLNPVTWGCFTGKEIVTPTMIEAVSFRAW
AEEAFGIWTEWRHVYPPRSPSAKLLREIRDNYWLVNIIHHDFTENNGLWKMLLEA
>A0A0R0E2T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas acidaminiphila|TrEMBL
MTALSFEFYPPKTDDQRAQLDRTASKLKVHAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GLQAAPHLSCVGGTREEIRELLKLYRAIGVRRIVALRGDLPSGMGFPGDLRYASELIAFI
RAEHGDAFRIEVGAYPETHPQASDALADLRHFKAKIDAGADAAITQYFYNADAYFQFVDA
TRKLGVDVPIVPGVMPISNFSQLRRFSEQCGAEIPRWIAKRMQAYGDDVDSVRAFGADVV
AALCERLIAGGAPSLHFYTLNLARPTSAVLQRLGHG
>A0A453M7J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aegilops tauschii subsp. strangulata|TrEMBL
MPINNYKGFVRMTGFCKTKIPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKT
LHLYTLNMEKTALAILMNLGLIEESKLSRTLPWRPPTNVFRVKEDVRPIFWANRPKSYIS
RTTGWDQYPHGRWGDSRNPSYGALNDHQFTRPRGRGKKLQEEWAVPLKSVQDINERFVNF
CEGKLKSSPWSELDGLQPETTIIDDQLVKINSKGFLTINSQPAVNAEKSESPSVGWGGPG
GYVYQKAYVEFFCAKEKLGQLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFP
GKEIIQPTVVDSASFMVWKDEAFEIWSRGWACLFPEGDSSRELLEQIQKSYYLVSLVDND
YISGDLFAAFKEI
>A0A4S9ZUG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEVTAPEAPQ
KVNGATNGEKHQEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A2V7EI28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MGTMLYNKGVFINQCYDELNLRAPDLVRDVHKAYRKAGAEVLETNSFGANRIKLEQYGLA
AQVAEINRAAAKIAREVAEDDLLVAGAVGPLGIRLEPFGPTSLEEARAVFREQLQALKDG
GCDLFILETFADLHEIEQGILAAREVDPNIPVIAQMTIGSDCHTPYGVTVEDLAQSIDAF
GADVVGLNCSVGPQIILDAIEKMAPVTRRKLSAQPNAGMPRDVSGRSMYMASPEYMATYA
HHLVQAGAKIVGGCCGTTPDHIAAMVEGVRPLSPRQARVAMKERRQTHPDLPPEDPGVEP
VPLAERSKWGRKIAEGEFVTSVEIVPPRGVDATKMLRDTAALRDAGVDAVNVPDGPRAQS
RMGALLTSVLIEQQVGIETVIHYCCRDRNLLGMLSDLLGAAAVGLRNMLLITGDPPKMGP
YPNATAVFDIDAIGLTNLVSNLNRGLDPGGNAIGQPTKFTIGVGVNPAAIDPGQELKRFE
WKVEAGAEYAITQPVFDVMQLEKFLSTIEHVRIPIVAGIWPLVSLRNAEFLANEVPGVVV
PPRIIERMRVASAKSKEDGVAEGISIAREMLERVRPYVQGVQVSAPFGKVELALEVFRDT
LVPTEARTA
>A0A6P0H245|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Modestobacter muralis|TrEMBL
MKRVLTVRDGATREALRRAVTDVGFEVIPFKKTEQAVLDHVPRDVALTVTASPAKGQDAT
VDLAVALAGHGYAVSPHLSARQVRDRAHLTDVLARCREAGITGVFVVGGDPSEEDTGFAD
AHALLVAMHEIGHSFTDIGIGGHPEGHPNAPDELLFGALVAKAPLATHITTQIVFDPKVI
LTWARELVARGIDLPVHVGVPGAVHRQKLMRVSGGLGIGESAKFLKKQQNLLWRFFIPGG
YSPDKIIRGLAPHIGKPDNHLHGFHVFTFNDLEPTEAWRQQLLRDLA
>A0A074JKD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus salivarius|TrEMBL
MTSQTPSLSFEVFPPNPAVGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFKYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSGLLTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHEATHSLFKHHSQVSAL
>A0A158QR54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemonchus placei|TrEMBL
GSNPSLHERSGSDDEHLTFEVGRRRYIPLHERINRRVQDKTPFFSLEFFPPKTANGVANF
FTRLDRFNEGGPLFVDITWHLASDPANMNRETSSSSIAAGCLDYCRVDTMLHMTCAQYSK
EQTIKHLEQSKSVGLRNILALRGDLPHMDTDGVPIYKYRALDMIRWIREEFGDYFTICCS
GYPAGHPESPSYKADLLYLKSKCEAGAQFIITQLFFEAEVFEEFVRDCREIGITVPIIPG
IMPIMGYDSIRRIATLSQLTIPESILSDLEPIKHDDDAVMKYGTVKVTLRITSFVC
>A0A445L562|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycine soja|TrEMBL
MKIIEKIRAASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGTT
ADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVQHIRAKYGDYFGITIAGYPEAHPDVIESDGLATPEGYRNDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKVSRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALSDYQFMRPRARDKKLVEEWAVPLKSVEDIYERFRLYCLGKLRSNPWSELDGLQP
ETKIINEQLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKL
DALVDKCKDRTSLTYMAVNKDGSWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFNVW
KDEAFEIWSRGWASLYPEDEASRKLVEEVGGSHFLVSLVDNDYINGDLFAVFADF
>A0A523AYG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hadesarchaea archaeon|TrEMBL
MKKAFSNLMKAISEGKFVYTGELEPHRSIDLSEVESWARTLKEAGIVAANVTDNPRSDSA
ISSMVASYLIQRNTGLETIYQLRTADRNRLALLSDVLGGAALGLRNILALTGDHTRIGTT
PSSKPVFDLDSTGLIALIHKLVYEGKDLDGNELKGPRPEINVGAAANPNMDPLEIEILKL
ERKAEAGADFFQTQVVFDVEVARRFLREIEHIKVPTLVGIFPPRSYGQAEFFDKYVPGVR
VPKEFMEAFARFRTIEDKQKRSEKINEYNVEYFSNFIREVKKERACAGIHIMAVGYPEVI
RPLMESVK
>A0A7J2XXG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Korarchaeota archaeon|TrEMBL
MEIGIEIVPSNLPRFLRSLSSVIGYADFISLPECPFGRPLPSPLILSVVAKGLGLEAIPN
YRVMDRSELGFISEIMALSEVGIKRVVIVRGDLPSIGMPTSLNPVRAIELIKEYGIDIDV
GVATYIKPSETLRAKIEAGADFVVTQPIQDVEELSELLDFLGDIPLYTMIMPGMEDLDLN
VLREMGLNEVRKVDYKALLQDINKTRVRGVIISSPKGVSKALEILR
>A0A736KKG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Rough O:-:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A229XKN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neosartorya fumigata|TrEMBL
MHVKDMLTDNESAGRVGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVNAALSAAYKAGCTNILALRGDPPRDKEA
WEATEGGLRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSSF
VITQMFYDVDNFIEWVKKCRAKGITVPIIPGIMPISTYAAFIRRANWTKARIPPDWLEAL
EPVKNDDAAVKEIGKRLVADMCRRLLAAGINHLHFYTMNLAQATQAVLEELKLIPSEETP
LQRPLPWRPSLALNRRGEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDA
YGIGLKGTNEQNIKLWGEPKSIRDITQIFVRYLEGKLDRLPWSDSPISGEANAIKDNLVQ
LNSRGLLTVNSQPAVNGVRSSHPVFGWGPKNGFVYQKAYLELFVPPYLLDELIARIEKNP
DLTYHAVAKNRELRTNTRDSPNALTWGIFAGREIVQPTIVDTISFLAWKDEAYRLGEDWA
KCHDASSPSRKLIQDIMDNWYLVNIVNNDFHNTYDLFDLFNGLEVKDLDLEVGPDTAETK
SQPNGAAPEEVAIKN
>A0A0C4UT20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria biramulata|TrEMBL
AYGIHLGTEMCKKILAHGIKTVHLYTLNLEKSALAILANLGLIDMTKIKRPLPWRPPANV
>A0A4R3RZB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium azibense|TrEMBL
MALNTGDRRNIGISFEFFPPKSEEMEGQLWKTVAELQDWDPDFVSVTYGAGGTTKAPTLT
AVTRFLNETPLATASHLTCVGATKEETHQVIDHFRKAGVKHFVALRGDAPGGAGVPYEPH
PGGYANAAELVAGLREIGDFEISVSAYPEKHPESLDVAADIDMLKRKADNGADRALTQFF
FDNDNFERYLEKVRRSGVKIPIVPGIMPIQNLTQLKRFASACGTVIPAFLDERFAGLDDK
VEERAKVAVDVAVEQIEDLVRRGLNEFHLYTMNRSPLVSAVLTNLGLRREGAKRAAGAAA
>A0A498D417|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter cumulans|TrEMBL
MSLLSSYFQQNQFCILVEYLTSLNEIFPVKKQFAGYPAVMTLADRVHSDHDTSPLEASKL
YPQDLEKVLHFAGKGRDIHDFENFLKQARKADIQNLLLLTGDKLKEHSNGENGTARSRYL
ESVNAVMAAKKAGGFCIGVAFNPFKYTEAERDAQYLKLHKKIKAGADFIITQLGYDIQAL
KQAKAFLTQHHYSQKILACVMPLSLARAKFMLKNQVAGIVITPYMLKVLEEEKQAGLSER
VYLRCALQILICKQLGFAGVDLSACHKPAEQALLESYIEQYRHLNLDALEKLWNELWQIH
TGAEFQPELSYFSRPPSSRQLFKYHQLHLMHDALFDSKLGKGVGRFIFKAQIWQKATAAK
TLLKTEYISKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVQQTQVLKEKLIPTVPIEVRGTSSWKNWYLAAEA
>A0A345LZS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia huaxiensis|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSEEMEQTLWKSIDRLKNLKPKFVSVTY
GANSGERDRTHSIIKDIKDKTGLIAAPHLTCIDASSDELKAIARDYWNNGIRHIVALRGD
LPDNSRKPDMYAVDLVELLKGEADFDVSVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPAWMSKMYE
GLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A494U5V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas veronii|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKC
>A0A6L7ZZ08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MNPPLKLSFEFFPPATDRDEAALWRTVEALTPFGPRFVSVTYGAGGSTRARTDRIVRAIK
RDTGLEPAAHLTCVGAVREEVDAIAKGWWEAGIRHLVALRGDPPKDADRYTPHPGGYENA
AALVAGLRRVADFDIAVAAYPECHPDSPSPEADLDNLKRKLDAGAACAITQFFFEPATFL
RFRDRARAAGIEAPIVPGILPITNFARAVRFAGICGATIPAWLADLYRGLDDDPETRSMV
AAAQATELCQRLQAEGVEAFHFYTLNRPALTAAICRRLSVRAPLEEAA
>A0A1V2LHJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pichia kudriavzevii|TrEMBL
MKITEKLQQAHRAEDAPATFSFEYFTPKTSQGVQNLYDRMDRMYNLNPLFIDITWNAGGR
SSNLTSEMVHTTSTVLGLETCMHLTCTNMPLELIDNALQQAYDSGCQNILALRGDPPLDG
SESTGDFKYAKDLIRHIRNKFGDYFCIGVAGYPENHPEEADEMKNLQYLKIKQDEGADFV
VTQLAYDVNIFIEWVQKCRQVGITMPIIPGIMPISNYNAFLRRAKWNEVSIPQSFLDRLE
PIKDDDAKVREEGALLMTEFCSKLLESKLINHLHFYTMNLEKSTLMLLENLNLISCASKI
NYENENSKPWRRSLNPSRETENVRPIFWKNRKFSYIQRTNAWDEFPNGRWGDSRSPAFGG
LDLLEHEIIRHSPAKILSLWDKPSNPMELGNLIIAYLENRIHCLPWSDTQVTSEIEPIKQ
SLIDLNKHGVLTINSQPKINGVRSDDLVFGWGPSNGYVYQKQYLEFLLPKSKMDLLISKI
ESVNKEYNYNILNYFIADADSNNVLGSNVIESADVNAVTWGCFPGKEVAQPTIVEKVSFI
AWKDELFLILKKWSNVLKSSLVDAQTQPDENDRLSDLNSANFIESLINEYVLVNIVDNDY
VHPSDRIFSLFNDI
>K1QN08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crassostrea gigas|TrEMBL
MPELLNGRATNGNSNYKETPYSPVHESEYGEYRSLTERMNRRIQSGDPWYSLEFFPPRTA
NGAVNLVSRIERMSEGGPMFCDITWHPAGDPGNTEKPTSSTCMAATMLNYCGVETMLHIT
CSNQDEDGLKRNLQKAKDIGLKNLLALRGDPPDGGDTWKKQEEGLNYATDLVKVIRREHG
DHFTICVAGYPTGHPESTSYGDDLRHLKEKVDAGANFIITQLFFKPETFFQFLRDCREIG
ITCPIIPGVLPIQAYQSLRHIVKLSRLEVPKEILDTIEPIKDNDEAIRNFGVEQCFQMCR
ELLKHEDVHGVHFYTLNREVATIEILRRLGMWVEEPCKPLPWKQTANYVRCKEDVRPIFW
RSRPKSYIHRTSNWDEFPNGRWGNSSAASFGDLTDYYLFYLKHKTPKEDLLKMWGEELNS
EQDVWDVFHCYISGCPNTKEVKVCSMPWNDEELSPETNLIKEQLEAINKRGVLTINSQPN
VNGAPSSDSKVGWGSPNGYIYQKAYLEFFTTKENGIALKKILKNYPQVNYHIVNKNGEED
TNCDLTTPIAVTWGVFPGKEIIQPTVVDPIAFKTWKDEAFELWKHPWGNLYPEGSQSRKI
IDHIFDSYYLVNLVDNDFPKDSCLWRIVEQMLEAGRQTSSVEEMDVNGQW
>A0A8B8M8X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Abrus precatorius|TrEMBL
MKVIEKIREAAATDSNRVVFSFEFFPPKTEDGVDNLFERMERMVAHNPSFCDITWGAGGS
TADLTLEIANKMQNIICVETMMHLTCTNMPIEKIDHALQTIKSNGLQNVLALRGDPPHGQ
DKFVQVEGGFACARDLVKHIKAKYGDYFGITVAGYPEAHPDVIGSDGVATLEGYQNDLAY
LKSKVDTGAELIVTQLFYDTDIFLKFVNDCRQIGITCPIIPGIMPINNYKGFLRMTGFCK
TKIPADIIAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALAILM
NLGLIEEAKISRSLPWRRPTNVFRVREDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSC
NPSYGALTDYQFMRPRSRDKKLTEEWAVPLRSVEDIYERFRLYCLGKLRSNPWSELDGLQ
PETKIINEQLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEK
LDALVDKCKDRMSLTYMAVNKDGRWRSNVSQSDVNAVTWGVFPAKEIIQPTIVDPISFNV
WKDEAFEIWSRGWASLYPEGDASRKLVEEVGSSYFLVSLVDNDYINGDLFAAFADF
>A0A8D6UI65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. corylina|TrEMBL
MIDPDTPSLASTITEAYSLEVSAKHIAGLAAAAPRIMRGATIAIPYLPNQDDDARLAAAR
MVRTLGFQPMPHLSARRIASREQLHAFVSRAVDDAGVERCLVIAGDPPAPLGPFPDSLSL
LDTGVFERSGIRTIAVAGHPEGHPSMPAADRWEVLQRKCRSIAERGMAPLIVTQFAFDAD
IVLRWLQALRAHGIAYPVRVGVPGPAGVAVLARYAASCGVSACASMLSKYGISLGKLLGT
AGPDRFVERLATGLTDAHGEVRMHFYPFGGIAQTVAWVEQYRSRSARV
>U3U6W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pantoea carbekii|TrEMBL
MSFFHAIQHEVLNQRLCELDGQQLNISFEFFPPRFNEHKIEESLWHSIYRLSKLKPKFVS
VTYGANAGERDRTHNIIKDIKKRTGLEVAPHLTCINATRDKLLNIASNYWENGIRHIIAL
RGDLPVKGCKPKMYGSDLVKLLKEVGNFDISVAAYPEVHPEAKSAQADLINLKHKIDAGA
NRAITQFFFDVENYLRFRDRCVLIGIEVEIVPGILPILNFKQAQKFATMNNVRMPNWIHT
MFQGLDNDLETCKMIGANIAIDMVKLLSCEGVKDFHFYTLNHADMSIAICHTLGIRAQLA
A
>A0A0U5FIS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. citri|TrEMBL
MPSGASTITDTYSLEVSVKDIGALTNAAPRILPGSDMFIPYLPGQTEAARLAAAQRVRRL
GFEPVPHLSARRIGSLEELQAVIARLVGEADVTRCLVIAGDPSTPKGPFADSVSLIETGV
FERSGIRTIGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDADIVMTW
LEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGNAGPDR
FVDRLVSRLTEAHGDVRLHFFPFGGIAQSVEWVAHYRSCEASQDRVSSVAAD
>A0A2A4JS11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heliothis virescens|TrEMBL
MEGIKVTELIKNKGNFSYSFEVTPDVSEEDIDNLKVDPLFYSVTWHAKSHQCRDLSIDPI
KTASLLRSKQKQVLMHLSCDRMRSQYLTEVLTFLQENNICNLFIVLGEGFDPDNSDFKST
SEMIKFIREKTGKYFCIGIAGFPGCLEQKILEIKDKIDIGADFILTQAFFDVEAFKSFKD
RFTKMGITVPIIPGVFPFETLKQLEGFIKMCRIKVSDDLLEAVNDKEKMNKPCTELIKQL
IEHLRSKCSTTHFHFFTINKLQNIQNLIEEIN
>A0A6B1GA51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MLLLKDASGRRRLLQHAQWELIPLRNLAEQLPHLPPQSPVSVTASASKTLEDTLDLTAEL
CALGHHPVPHVAARMVTSRDHLEELLGRIESMGLSEIFLVGGDVASPAGPFDSAVGLLEA
LREVSHSLVHIGVTSYPEGHALITDAVLHEALHVKQVLLAEAGIEGHAATQMCFHPKAIL
EWLAAERDSGLNLPVHLGIPGAVDPARLLRIGTRLGVGASLRYLRKNTGAVARMLRPGGY
DPSGLVDRIAPHAERLDIAGLHVFTFNAIADTVAWRESALAETSSRRR
>B5GMA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces clavuligerus|TrEMBL
MALGIPSTRNDHAHSIRELLSRGGRSYSFEFMPPRSESAEVGLWAAIRRLEALSPTFVSV
TYGAGGSTRGRTVNVTGRIAQETTLTPVAHLTAVDHSIAELRNILGHYADQGVRNILALR
GDPPGDPLGPWTRHPEGVRYAAELVELIKESGTFCVGVAAFPEMHPRSADWEAEIRHFVD
KCRAGADYAITQMFFDVDQYLRFRDRVTAAGCETPIIPEIMPVTTIRSLERIPTLSTAAF
PADLAERMLAAQNDPKAVRALGIEHATAMCRRLIAEDAPGLHFMTMNRSKVTTEIYQDLG
LHL
>A0A804JBA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Musa acuminata subsp. malaccensis|TrEMBL
MKVIDKIRGAAEGDGRTVFSFEFFPPKTEEGVENLFERVDRMVAHNPNFCDITWGAGGST
ADLTLDIANRMQNMICVETMMHLTCTNMPVEKIDHALDTIKANGIQNVLALRGDPPHGQD
KFVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDMIQGDGGATQEAYNNDLAYL
KRKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPPEITAALDPIKDNEDAVRAYGVHLGTEMCKKILSHGIKTLHLYTLNMEKSALAILMN
LGLIEESKVSRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTVGWDQYPHGRWGDSNN
PSYGALTDYQFMRPRSRDKKLQEEWATPLKSVDDINERFMKFCLGKLRSSPWSELDGLQP
ETKIINEQLSQVNLKGFLTINSQPPVNGEKSDSPAVGWGGPGGYVYQKAYLEFFCSKDKL
ISITENCKALPSLTYIAVNKEGEYVSNVVLNAVNAVTWGVFPGKEIIQPTVVDPASFMIW
KDEAFEIWTRGWARLFPEGDPSRELLAQVQKSCFLVSLVDNDYIHGDIFAAFKGA
>A0A2V6WTC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MTNPLRAALGAGRFCYVVELVASALTREARLLETASGLARLPQVVAGSVTSYAGGAMGHD
PLRVAAAARARGLTPNIHLTCVSQDRNDLGKTLADMHALSLENVFALTGDYPSAGDQPPV
FDLDSVQLVHLIDELRRGGMVFHTMVAVSPFKYTEADCVYQYVKLEKKIAAGADAAVTQV
GWDARKFEELKRYLDERGIRTPLLGNVYVLGPKTAERMATGRPAGCWVSPELLAAVRAES
EAKDGGRLARLERAARTVAVLRGLGYAGAYIGGTHDPAQIAWIIRRVGELASSWERLAAE
LRYGAASGFYLAAARPRARRGRRDALPRALDRLGRLLPVTRDTPLRRALTRLLAWIDRRP
PAAALLERIELAIKKPMFGCQACGNCVLGHLEYVCPQTCPKQMRNGPCGGTDNGRCEVVP
DKPCIWVAVHDRAKASGSLEGLKTYLPPPHRQLRDTSSWINYFLDRDSRP
>A0A7R9M3S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oppiella nova|TrEMBL
MIESEKLTDKLNGERVVSNGAVRKTSASQAPYVPLIARMRQRMSDGNGPFFSFEFFPPKT
REAAINLIARFDRLRQTGPMFCDITWHTAGNPGADTETSSITIAGVALNYSGLDTMLHIT
CVGMTEPDLRRHLERAKDLGIRNILALRGDRVAIDSTESQEKVDFRYAVDLVRYIRREYG
DYFTIAVAGYPGAHPESVSVEEDLQRLKEKVDAGADFIITQLFFKSDLFVKYVKNCRKIG
IEVPILAGIMPIQSYESLEKIVRLSKLDIPDTILKDLNIIRSNDEAVRNYGIQWAVGLCR
QILAANVTPGLHFYTLNREMATCAILKQLGLLTQVSKPLPWWPAANHKRAGEDVRPIYWS
GRPRSYVCRTQSWDEFPNGRWGRVDSPAFQTLENYYLFLEPKLSRKELLQMWGQELTGEQ
DVWDVFHCYVSGLKNKNDKKVSVIPWNMDALSDETALLVKQLSQYNKRGVLTICSQPNVN
GVDSTHPIHGWGPKGGYIYQKAYLEFFTNEKNVLALMEALKNYPLVNYQIVDSSGKKSYS
NFESNKAIAVTWGVFPGREIIQPTVVDPISFKVWKDEAFGLWTQKWAQLYSGDSLSRKVL
DDIHDNYYLVNLVDNQFPKECCLWQLLEDMFTIRANFELNKFINYFF
>A0A3S4TVH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter pneumotropicus|TrEMBL
MSYAKEINNLNQNIADFNKKINVSFEFFPPKNEKMENILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDATPQELKKIAQDYWDSGIRRIVALRGDEP
KGYDKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHIIT
QFFFDIDSYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPNWLAKAYDGL
DEDPTTRNLVAASVAMDMVKILSSEGVNDFHFYTLNRSELTYAICHMLGVRPSV
>A0A0A1GR85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDRLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A496X2W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDELQQNAWPLSFELFPPKTEQGQENLSAARAQLARYKPTLFSVTYGAGGSTRDNTRDIV
LDTRSAGLEVAPHLSFGGDSEQAVLDLLTTYRDAGIAHVVALRGDLPAGMGGAMQLVHAN
ELVAFIRQHFAEHFTLHVAAYPEIHPEANSYQDDIHWLGEKFNAGASAAITQYFYNIDAY
WYFIDQCQKAGIDQPIVPGIMPITNFQNLARFSLNCGAEIPRWMQQQLQQYGDDLDSVKK
FGIDTVSRLCEQLIDGGAPGLHFYTMNQVEPIATILANLGRRATDQTT
>A0A3G8ZFH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epilithonimonas vandammei|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFKPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEPTKGGHKYASDLVKQIQDLGTGKYLHEEILSEENNSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKFFEFVKQAREIGIDVPIIPGIK
PIATKTHLQMLPQVFKIDLPEALINEVLKCKTNNDVREVGIEWAINQSKELLDFGIPVLH
FYSMGKSDNILKIGREVF
>A0A0U1PTD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter toxicus|TrEMBL
MTAQCSETGPEADCPRVPFSFEVYPPRTAAATTALLGTVDRLAASGPDFISVTYGVGGSS
RTASLDILRYLQEHTETEALAHLTCVGSTGAEASRLVHEFFDAGVTRFLALRGDLAEGEC
FQGELGSAAELVQLIHRVQAEREPYSAVAVPGIPNAQRVEVTARPRAQVAVAAFPNGHPR
SRSAAQDIDALLAKEAAGADFAITQLFFHASDYLRFVDRARSAGVRMPIIPGVMPVTTPA
RLRRMLELSGEDVPVDLAIALDVEPDDEARTRIGIEYAARLVRTLVDAGAPATHLYAFNR
HEAALGVLSVAGLLPSTFAPFLSERIT
>A0A2T4XU55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter cloacae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A6G2DLL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIILALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIELIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNEHFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A116KUQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHISTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A6I3FLY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVVRTSYSLEFFPPKDEEGEARLWAALEALEFIAPEFISVTYGAGGSTRNRTIGVTEEVR
QRTKIPTVAHLTCVGSSRQEIISILHMYRAAGIRGVLALRGDPVGGPRAPWTPMPDGFTH
ADELVQLIHEFGGFDIGVAAFPDGHPSSNGDAKKDIDVLLRKEHLGATFATTQFFFDVSK
WEQLVYALQARGSTMPIIPGILPITNVKQLQRMAELGGTDIPPAVSSAFSAVEDDVDAVH
ALGIELASTLCEDLLRAGAPSLHFYTMNSATATKEIYRNLNNAH
>A0A5H9BA72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Stanleyville|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3Z3GAS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Java|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A538HA09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSKLEDAIAGGRFVLTAELLTINSGGLDAVSERFEPYEPWVDAVNATDNTSAHAHASPVA
VSIALKQLGMEPVMQLVCRDRNRLALQADIAGAALHGVENICCLTGDDVTAGDQPESRRV
FDLDSTQLLVTATGMARGRYLSGRAIHPAPHLFLGAVENPGAPPFDYRVERALEKVRAGA
RFFQLQVCFQKELLERFMAEAVARGLADQAALLPSICLVRSTASLRFIDEKVPGISVPPE
LIERCERAPDPEAECFELACELAEHARALPGVAGLHLISFRREAGIARLCQRLGIPTRVE
RESRGHGSSVAV
>A0A6B3JBU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter agglomerans|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSDMEETLWTSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMSAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAAAA
>A0A6A6Z8D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mytilinidion resinicola|TrEMBL
MEKVTDKIAALPSDAHYFSLEFFPPKTPMGFANLQNRLERMSRALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMSRSLVDDALEQAKALGIRNILALRGDAPRSEE
YRNEEKPEEEDSNNDFTWAIDLVRYIRKQYGDYFCIGVAAYPEGHSDQSHPQDQDPLFDL
PYLVEKTKAGADFIMTQLFFDVEAFDRFEKLLREHESGVFKTIPIIPGLMPIQSYQILRR
VTKLSHAKLPSDLLTRLDAVKGDDELVKQVGVDILSEVIDHVKASPSPVRRGFHFYTLNL
EKAVAHILERCHLIPPIQPDEDEEAVVVDLSKDFVPPETALQSKDRRRLSSVNSGPRNRV
VVERHTRSSNTSFEAREDEAGIPRDAINTRANTLAISEGEGSLGREATWDDFPNGRWGDA
RSPAFGEIDGYGPSLHLPTPQALKLWGHPVTVEDVSNLFRRHISGELDALPWSEEGLNPE
TNIIRDELLRLNGKGWWSVASQPAVNGVKSTDPIFGWGPKNGFVFQKPFVELFIPSADWL
KLQARLDQTDQMTYFAGNKAGHFSASNEESVNPVTWGTFAGKEIITPTIVESVSFRAWLE
EAFSIWAEWRRIYPARSATSKLLGGIMNDYWLVNIIHHGYLEKGALWDFLTEG
>A0A1E7RCP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter qingfengensis|TrEMBL
MSKLSTYFAQQQFCFSIEYIEKQNAKPELVHHIAGYPACLAVADRVHSDEDRAPLDIAKD
IVQSDLLLHYSGKGRDIKELKIFLLQAQQRQHFDVLMLTGDKLKQHHFGLDDPTLRSRYL
ESVNSVQYAKNYDQRFHIGVAFNPFKYTHSERQAQYLKLHKKIQVGADFIVCQLGFDIEQ
LKRLMQYRQQQGWQTPVMACVMPLSYQRAKFLIEHKVAGIVIATDLFEQLKQEFQQDPQI
AEQRMYQRAALHILICKALGFAGIHLSGCEKKTQITKLEQAIQQYKNLTLQQCWQKYLNL
NQVNGQSGQIPENGAKETASAAQITKYYFLSRLHAVFFHSKLAMRFGYWLFSAKFWKKSQ
AQRTLLILEHASKHALVGCESCGQCRLDQTLYICPETCPKGLANGPCGGTTLDRCEFNDR
ECIHSQKFRIAEQVQQLNILKDQIIPTVSIESRGQSSWLNWFQSQQCSKELTRQKSSVSS
DHLQ
>A0A444I9L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MVLKNEARGRNIRVSFEFFPPKSEEMEGQLWHAVSQLQDWDPDFVSVTYGAGGTTKAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPTFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGISRRETKSAGAAA
>A0A155DPT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter hormaechei|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A3V3G305|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella thompson|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3V9S6M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Kentucky|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4T0LPD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia mellicola|TrEMBL
MKIVEKINESKDNKTPFFSLEFFPPKTDQGFVNLKSRLQRLSLLKPGFVSVTWGAGGSTD
ERSLELAAVARDLGLDVLLHLTCTNMEKSRLSWALDKAKELGIDNILALRGDPPRGHEYW
VESDKNLSHSSDLVKFIRDNYADNFCIGVGAYPESHKDSSDAAQDLKYLKLKQDLGADFV
ITQLFYDSDAYLNWLDKCLDIGIKIPIIPGIMPIQNVPSLRRLANLCGAHIPSVISDHLE
PIKNDDALVKDYGVELSTSMVRQLIDKTNSQKEKYGNLAISAAHFCTLNLEKSVRRILAN
LDWSSGLDASSLEPNGLTHNTTTGAVEPARLGNRLVAENGISHGHTADGPPPLSITAHEA
AVRALHALKHHPPSEDSGLPSSNKTSSGGNSLWDEFPNGRYGDIRSPAYGELDGWGASLK
LSSQNALKQWGYPVEVSDINEIFKKYINGQVASLPWFEENLDPESNSIKDYLFRLAEKGW
WTVGSQPAVDAVESSDQIFGFGPKNGWIFQKAFVEFWVPEHELEGLCKRLDGWKDGGYYA
GNAKGEMKTNFYEDTINAVTWGIFPGQEVVQTTIIEDVSFNAWREEAFEIWLEWSMLYSP
KSASQQLMKNVHDNYWLVSVVHHDYKDTNGLWEFLLS
>U5P990|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus ilei|TrEMBL
MTKQTPSLSFEVFPPNPEVGNAKLLRALENMQELAPHFISVTASNNKYNIKETTVALANH
IQNELSIPTIAHLPAIYLSKEKVADTLHDLDQVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKTEAPHFDVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVHHATKALFDHQPNLEVI
>A0A6B0DVU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MLLNVHYLVKYSLEITQDHIRKNHSNYLGGVEFITVPDNPFGKAGPGSVPMAYLLKERYG
KKTVATINTRDRNKVGIISEILAAIELELYGIFVVSGDKIKKGREVREIDVFQLISLIKK
YRYDYGSDIQIGATINPSRENELRIVRKKMENGADFFITQSIYNEDIILKNKWIRHLSVP
VYAGFMPLLSKKIITFYSKSFSIDEGMVKKLMDSYNLIEDNASLFIKIVKNTCDHVEGYH
IMPLGNEKFLEKISRVIKIC
>A0A6A3XCI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora fragariae|TrEMBL
MDPPQTLDTCDSRLLPNDSLATSVSAFIKWEEAAALEAFPLAVVPSNHPHTREKGSKMPR
VSSIHVTKQKERHEEADELAATKFVLDDSTVWTGLSTEDVNEALTLHGKALAMAKLMNCR
RERLERVKATRRGCCSGCTWCRVQNEFQLDVLLHLTCHLPTEQLKRALGLQRLKAKQDAG
ADFIITQFFFDVDNMIHWIADCKDAGITILPGYLSIQNYSSLCKFTSWCKTRVPESVLAA
LDTIKNDDAAVRRYGTQLAAETCQRLLAAGVNSLHFYTMNLPRP
>A0A6A3U4P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora fragariae|TrEMBL
MGKISDSIRSAYAARADDASTHPTVSFEFFPAKTNAGVFNLLTRVEEMGLALQPTFVTLT
WRSAFTDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNARAAGIRNILALRGD
PPIGAERWAPVEGGLSNAVDLIKLIREEHGDYFCVACAGYAEVHTESWNHPDLPPSNEAR
ALDLQRLKAKQDAGADFIITQFFFDVDNMIQWIADCKDAGITIPILPGYLPIQTYSSFCK
FTSWCKTRVPESVLTALDAIKNDDAAVRRYGTQLAVETCQRLLAAGVNSLHFYTMNLATT
VTQVLEGLKMLPARNQRELPWQSTLQRSTVEGEQVRPIFWSNRQASYIARTAAWDEFPNG
RWGDRTSPAYGELSEYYLAFKRPKLQRTDLWGTPQTEQDVWNVFVRFIDGHVKQLPWCEQ
ALSLESAAIRENLQWINSNGFLTINSQPRVNGAPSSDPSVGWGGDDGVVFQKAYVEFFVA
PEKMAHLVKVMRRDYPQLSFHALNRKGDEHRNTPLHSVTAVTWGVFPGTEIVQPTVVDSD
SFAAWKDEAFELWQTQWASAYPADSRSREVVQHIYDTYFLVNIVDNDYANDESDIFSIFT
RIITEAMDKEQLRARVLELETRREKMFDTLASFQSLQEELNGELRSVHSELAGVRSENLQ
LKEKVRQVQAQLALASL
>A0A3Q1M8J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos taurus|TrEMBL
MVNEPRGNGSPGPRWEGSSSGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKH
IRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>A0A4T0NNJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia mellicola|TrEMBL
MIVDSQFSDIMYIPDGFVNLKSRLQRLSLLKPGFVSVTWGAGGSTDERSLELAAVARDLG
LDVLLHLTCTNMEKSRLSWALDKAKELGIDNILALRGDPPRGHEYWVESDKNLSHSSDLV
KFIRDNYADNFCIGVGAYPESHKDSSDAAQDLKYLKLKQDLGADFVITQLFYDSDAYLNW
LDKCLDIGIKIPIIPGIMPIQNVPSLRRLANLCGAHIPSVISDHLEPIKNDDALVKDYGV
ELSTSMVRQLIDKTNSQKEKYGNLAISAAHFCTLNLEKSVRRILANLDWSSGLDASSLEP
NGLTHNTTTGAVEPARLGNRLVAENGISHGHTADGPPPLSITAHEAAVRALHALKHHPPS
EDSGLPSSNKTSSGGNSLWDEFPNGRYGDIRSPAYGELDGWGASLKLSSQNALKQWGYPV
EVSDINEIFKKYINGQVASLPWFEENLDPESNSIKDYLFRLAEKGWWTVGSQPAVDAVES
SDQIFGFGPKNGWIFQKAFVEFWVPEHELEGLCKRLDGWKDGGYYAGNAKGEMKTNFYED
TINAVTWGIFPGQEVVQTTIIEDVSFNAWREEAFEIWLEWSMLYSPKSASQQLMKNVHDN
YWLVSVVHHDYKDTNGLWEFLLS
>A0A5Z8QKI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar 4,[5],12:i:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5T0IPM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKKQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A1X6Z4P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limimaricola soesokkakensis|TrEMBL
MTRPAVSFEFFPPKNIEGSFRLWDTVQALAPMGPEFVSVTYGAGGTTRKLTHEAVDAIHK
KTDLRVAAHLTCVDATRAETMEIVDGYAKAGVEEIVALRGDPPKGTGGFRPHAEGFSGSV
ELIEALAARGNFRIRVGAYPEPHPDAAHELADVEHLKRKFDAGAHSAITQFFFEADTFFR
FRDACAKAGIEGPIIPGILPIENWNGARKFAAMCGTSIPQVVADGFEHAKDQAEADLLAT
ALATELCDKLIAGGVEHLHFYTLNKPDLTRDVCHALGIAPKATLSEVA
>A0A6N6Q983|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella tritici|TrEMBL
MGFYGLSRRPDIGQTTRVSFEFFPPKSEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDVKPAAHLTCVDATREEVDRVVREFAALGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPSWLAERFE
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTEAAL
EVA
>A0A536NLR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVRPLGGLSVGQALAEFLRTPRYEIFPTDDVLDLVAAYVPKEVTLAVTASPRRGLPATVQ
LAARLSQLGYRAVPHLSARLIRDRAELGQILEALKAANIQNVFVIAGDAREPAGQFPDSM
SLLEALPPDHGLTEIGVTGYPESHPFIHDDVTIQAMWDKRRLATYIVSNMSFDPATVKRW
VERVRHRGVELPIHIGMAGVADPARLLRLSTKIGVADAARFLRGHPSWLARMFRPGGYEP
GRFVSALLPELAQPDRRVGGLHVFTFNEIEPTERWRREMLTRLA
>A0A4R9IQK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira bourretii|TrEMBL
MNQILLEVIPRDVPTLLSEVSYVKNNFSQISGINIPDLLRFETRSWVAASKIQNIFPNVI
PHLRAIDFDLDHCDHIVEFLQKNNLSSVVVIKGDPPTDMSRKVYQTTSTKLIKKLKKEMS
SLKVYAAVDQYRSGIKEEFDYIEMKIDAGADGFLTQPFFDLRLIDIFTEKLRGKEVYIGI
SPVTNEKSQSYWESRNRAYFPKDFQLTMDWNVKFAKEVIGYCSQNDFNTYLMPIRINLEV
YLSGIFK
>A0A1M0SKB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7Y1VHJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MNVTNLNATELAAVRNVIENLHYELIPLSNVIEQAAFLPERATVSVTASPAKGMQATIDL
SLQLQDMGMHVIPHFSARLTTDRAELEANLKAIDKAGIHRVFIVGGDADPPGEFFDAFSL
LQAIDDIGHTIDSFGITGYPEGHPIISDELLEQAIVDKVPFAQYITTQMCFEPDTITDWI
GHQRDRGIELPVYLGIPGSAELKKLLGISARIGVGDSIKFAAKNPKLIGRLVKPGGYSPD
ALILGLAPALTDDRINIEGFHCYTFNQVERTEEWRRDMLEALS
>A0A8D6XT49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus thermophilus|TrEMBL
MTSQTPSLSFEVFPPNPAIGNEKILLALDDMKGSAPHFISVTASNNKYNIKETTVPLADH
IQNDLAIPTIAHLPAIYLSKEKVADTLRELDAVGVNRILALRGDIIPGVEPLKDFRYATD
LIEFIKAEAPNFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGINVPIYAGIMPILNRNQALRLLKTCENIHLPRKFRAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETARHIYEATHSLFKHHSQVGAL
>A0A8H8LW69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceratobasidium sp. AG-Ba|TrEMBL
MKVTQKIEQAEKDGRIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFVDITWNAGGRTS
DLTAELVKTCQGVIGVETCMHLTCTNMPQEKVDIALKEAKAAGCRNILALRGDPPSGQEE
WTTVQGGFQHGIDLVRHIRKEYGDYFDIAVAGFPQTITLPEAEAAQEMQWLKEKCDAGVN
FIFTQMFYDADVFIRWVKAARAAGITIPIVPGINPIQTWNGFIRATTLSKTEIPQDLMDA
LEPHKNNDEKVRELGTKIVAELCRKILSADIGIKGLHFYTMNLEKGTKMLLEELNFVPRV
ETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTPEEGLKIWGTPTTVEDVKNLFAAFCTNQLKALPWSDQPPSTEMKVIGQQLA
RINELGYLTINSQPAVNGARSDDKVFGWGPKNGYVYQKAYLEFFVSPDQLNTLIRRIERD
PNVTYYAINKQGDLKTNSTSEGPTAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGCQ
WAQIYEPGSPSRKLIKNMMDEYFLVNLVHNDFQDREAIFRPFFADAGLKLNGEEPVAKLN
GEIAGLKLNGDSHPKAIKA
>A0A661K5E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MAFKEALQSGKFTVTAEVGPLKGTDTTEVLEVAELLRGKVDGVNVTDQQSAVMRLGSLVT
CHLLIQKGLDPIFQMTCRDRNRIALQSDLLNAHVLGIKNVLAITGDYPTLGDHPDAKAVY
DIDSVQLVWTINRMNQGYDLAGNELQGKTDFFVGAVVTPITDTEAAFELQLIKMEKKIEA
GARFFQTQAVYDVDAFARFMKRAEGFGVPILAGIIPLKSVGMARYMNKNVAGVFVPEHLI
EEMSKAEDKAQRGLEIAARLIKDLKDLCQGVHIMAIGWEKKVPEILELAGLA
>A0A777S8F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A4Z1AF44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira congkakensis|TrEMBL
MHISQILGKKQTTISFEFFPPKNEEASADLFQNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQKETGLTIVSHLTCVGSTKDEIKEILKRYEKSGIHNIMALRGDPPKGQTEFKQT
ENGFAYAGELVSFIKKEYPEMGIGIAGFPEGHPSTPNRLKEIEYLKWKVDQGADYICTQM
FFNNNYFYDFVERCEIAGIKVPIIAGIMPVTSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDSYAENVGIHWATEQVRDLLDHKVAGIHMYTLNKSKATRKIYESLGVRNFDTIG
>A0A1Q5VS98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas allosaccharophila|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEAKSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDNDQMTRNLVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKG
>A0A3E2VMZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterocloster citroniae|TrEMBL
MKIRDILAQGRPTLSFEVFPPKTEDAYDTVERAAAKIATLKPDFMSVTYGAGGGTSDYTV
GIASDIQKSGVTPLAHLTCVSSTRDKVHSVLEELKNHGIENVLALRGDIPADGRTPREYH
YASELIHEIKQSGDFCIGAACYPEGHVESANKSVDMDYLKEKVEAGCDFVTTQMFFDNSI
LYSYLYRIREKGITVPVIAGIMPVTSAKQIKRITQMSGTYLPSRFLAIVDKFGDNPAAMK
QAGIAYATDQIIDLIANGVRGIHVYSMNKPDVAMKIRENLSEIL
>M5ED31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malassezia sympodialis (strain ATCC 42132)|TrEMBL
MAGDESCKITAKLAKAKAEGRTWWSFEYFPPRTPQGMSNLLDRIERMGKLGPEFVDITWN
AGGRTSDLTTQLVKTVQAYFGLETCMHLTCTNMPRSKIDVALREAKDFGCRNILALRGDP
PACGSEWEPHAAGFAHCHELVSYIRANYGDYFTIAVAGFPEGHPEATEGPEKEMEYLKQK
IDCGSDFIFTQMFYDLDTFVDWVRRVRAAGITVPIVPGVMPIQNYGGFSRAVARFRAHVP
PHFHAALDPVKEDDEQVRLVGTRLVGDMCRKILEHPDLDIHGLHIYTMNLERGSRMLLEY
LQLTPSVQQLNPLPWKPSLTPKRRDERIRPIFWANRAKSYVSRTDGWDEFPNGRWGDARS
PAYGDVDAYGMHPRLQKDEALALWGAPETLEDLQRLFVRFCAGELAALPWSETPIAKETS
KIGAQLMRLNERGFLTINSQPPVDGARSDDPVHGWGPKDGYVYQKAYLEFFVAPAQLDEL
LHRIEAHPQITYHAVNAHGDMRTNTTSDAPNAVTWGCFPHCEIMQPTIVESISFLAWKDE
AFELGRRWAGLYEPDSRTHQLLSHIFDTYFLVNLVHNDFKQADAIFVPFQA
>A0A1S2AJE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A6L8CCG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermaceae bacterium|TrEMBL
MLQWAEAAGFSVQVKKFDPPASLDQGISVLIWTATWHASPPGGYSVNQLAAAEQQSKPAP
NVSFEFFPPKTDKMEAKLWESVARLTPMAPRFVSVTYGAGGTTRNRTQRIVTKIAQDTPL
LPAAHLTCVSATKEEVLQVAVDLWRAGIRHLVALRGDPPEGIGEKFEQHPGGFRNSIELI
EGIRAHDAVPDARFEISVSCYPEQHPHSRGWDRDIAFLRAKQDAGADRAITQFFFEPAVY
FAFLDRARAGGVTMPIVPGIMLQPNFKGMKRIADLCQVNLPDWLHELYEGTDEDTVTCEF
ITANVAAELCHKLSEQGVNEFHFYTLNRASLALSTCRLLGLKPQAVV
>A0A2S7V0L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio chagasii|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPPGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A086EXX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium brasiliense|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLRDIAQDYWQSGIRHIVALRGD
LPPEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTTMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A1C5N8T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MFIRDIFAQKKPVLSFEVFPPKKDSGLDNVISAVDELSKMPIDYMSVTYGAGGSNSKNTA
YIASHLKNNLSIPSLAHLTCVANSKDDIKVKLQEYKDLGIENILALRGDKPKDYDGEIFP
GYHYANELVEAIKDFGDFCVGGACYPECHPDSPSLDADIENLKVKVDAGVDFLVTQMFFD
NDEFYKFRDKLAKKGINKPITAGIMPLTNAGQIQRMAILSGGASMPSKFLRMISKYQDNP
EALKQAGIAYAVDQIIDLLSNDIDGIHLYTMNKPETAQKIVNVINNLFV
>A0A2E4TYR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARNPRFFSVTYGAGGSTQARTREVVR
AVGESGINTAPHLSCIGSEKAQLRDLLVQYREEGVESLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVKQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLEGGAPGLHFYTLNQAAPVLKIVDNLTD
>A0A0Q0CSB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. ulmi|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A8B8Z7S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balaenoptera musculus|TrEMBL
MVNEPRGHGGPSPRWEGSSSGSESSKDSSRCSTPVLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAVDLVKH
IRSEFGDYFDVCVAGYPKGHPDSESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSRLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
ALSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPSINGKPSSDPVVGWGPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGDNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLNRPPQNKSETEAP
>A0A2N8P1V3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces eurocidicus|TrEMBL
MALGTASTRTDHARTVRELLASGERSYSFEFAAPKSEKGERTLWNAIRRIEAVGPTFVSV
TYGAGGSSREGTVRVTERMATDTTLTPVAHLTAVNHSTAELRNIIGQYADVGIRNMLALR
GDPPGDPMGEWVRHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSDDWETDVRYFVD
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCDTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATELCARLMAEEIPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A084J2Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTSIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6J7EC29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MARIADLLARGRTFSFEFFPPKTDYAQLTLGRTIAELESLSPGFVSVTYGAGGSTRARTH
AVVEWVRKETHITPMAHLTCTAHTRADISEILANYTDAGVENILALGGDPPAAGADPGPS
DYSYALDLVEHIASADGFSIGVAAHPEMHPRSADRASDRRHLAEKLKRADFAITQFFFEA
DHYFRMVDELASLGVDKPIIPGIMPVTNKNQVKRMAELSGSVFPAWLAERIGDSGDEAEV
ARIGVEVATELCATLLDGGAPGLHFFTMNRSNATREIYGRLGLPTS
>A0A1D9IKZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas lundensis|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLMNTARHLATFNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVHVPAAPHLSCVGDSKSDLRGLLEQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDISNFVRKAHAGADSAITQYFFNADSYFR
FVERVQAAGVTLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVHSIQAFG
EQVISEMCERLLDGGAPGLHFYTLNQSEPSLAIWNNLKLPR
>A0A5U8C1Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGQPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>G4ZJB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora sojae (strain P6497)|TrEMBL
MGLALQPTFVTLTWRSAFKDEALWLRIGAHIQNEFQLDVLLHLTCHLPTEQLKRILKNAR
AAGIRNILALRGDPPIGAERWAPVEGGLSNAVDLIKLIREEHGDYFCIACAGYAEVHTES
WNHPDLPPSNEARALDLQRLKAKQDAGADFIITQFFFDVDNMIQWIGDCKDAGITIPILP
GYLPIQNYSSFCKFTSWCKTRVPESVLTALDAIKNDDAAVRRYGTQLAVETCQRLLAAGV
NSLHFYTMNLATTVTQVLEGLKMLPARNQRELPWQSTLQRSTAEGEQVRPIFWSNRQASY
IARTAAWDEFPNGRWGDRTSPAYGELSEYYLAFKRPKLQRADLWGTPQTEQDVWNVFVRF
IDGHVKQLPWCEQALSLESAAIRENLQWLNSNGFLTINSQPRVNGAPSSDPSVGWGGDDG
VVFQKAYVEFFVSPEKMAHLVKVMRRDYPQLSFHALNRKGDEHRNTPLHSVTAVTWGVFP
GTEIVQPTVVDSDSFAAWKDEAFELWQTQWASAYPADSRSREVIQHIFDTYYLVNIVDND
YANGACPHLATPIASALLCSDLRANVLCLCNYTDESDIFSIFTRIITEAMDKEQLRARVL
ELEARREKMFDTLASFQSLQEELNGELRSAHSELAGVRSENLQLKEKVRQLQAQLALASL
>A0A6J6KBB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTYISDLLAAGRTCSFEFFPPKTDDAARALEQTIAELEPLDPSFVSVTYGAGGSTRERTR
DVVINIERNIGITAMAHLTCVGHTRAQLDSLLDEYKAAGVSNILALAGDPIVDDNGVVAE
SEFEFAMELVELIKEKSGFSIGVAAHPEGHPRSEDLYSDRRHLADKLNVADFAITQFFFE
ADPYLRLVDGLSAFGCDKPVLPGIMPVTNAAQVVRFAELAGAAFPPHLAARFDAIADDPD
AVRALGVELASELCQRLLDEGAPGLHFYTLNRSTATREIAANLGLGDASSTGA
>A0A6J7S8A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTHPAGGPDLGTLLAQGGRSFSFELFPPKTDEGERALWQTVRDLERLHPTFVSVTYGAGG
STRDRTVRITAEIAEQTSMVPVAHLTCVGASREELRGVIAEYADAGITTILALRGDPPGG
PTAGWTPHPDGLQHADELVELIKSLGNFTVGVAAFPEGHPSSPDLDTDARVLAAKQDAGA
EFAVTQFFFRSRDYADLLERASAHGVSMPIIPGLMPVTNVAQISRFAELSGAAFPPELAA
RFEVVKADDDAVRKLGVEIAVEISNELLDMGAPGLHFYTLNRSTSTVQVYEALGLGSR
>A0A441BZ10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIARQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPYDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>N4VAU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422)|TrEMBL
MHIKSMLDETRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREHEK
WEATDDGFQYARDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGASF
IVTQMFYDGDNFVRWVGKVRERGITVPIIPGIMPIATYASFLRRAKHMNCKVPDEWMAAL
EPVKNDDVAVREIGKGLVADMCRKILAAGIHHLHFYTMNLAQATRMVLEELNWMPSNERP
LKHALPWKQSLGLGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPRSIKDIANIFVRYLETEIDTLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSSHPVHGWGPPNGYVYQKAYLELLVHPDMYPEIISRIEKNP
DMTYYATTKNGPLKYNAAHDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGTDW
AHCFEAGTPSRVLLDRIMNEWYLVNIVNNDFHQKTALFDLLDGLSIKEYNDIPSEPQVQT
NGQANGVSKEQASELSNGNVAPIPA
>A0A637CNX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Poona|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6G1G353|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eremomyces bilateralis CBS 781.70|TrEMBL
MEKITNKIQALPENGTYFSLEFFPPKTQIGLDNLVARLERMSGALRPLFVNVTWGAGGST
AGKSLQLAEICQKKLGLTTCLHLTCTNMSRALVDDALEKAKAMGIRNILALRGDPPRSEE
YAIVDGENGELDGDSNDEFKWATDLVRYIREQHGDYFCVGVATYPEGHSDQSHPEHQDPL
FDLPYLVEKTVAGADFIMSQLFYDVSKFDEHERMLREHPSGAFKDIPIIPGLMPIQSYQI
LRRVTKLSHASIPPELLERLDQVKTDDEEVKRVGVEILGEVIQHILQKPAVAHKGFHFYT
LNLEKVVSQIIEEGGLIPLFSISDDEAVSSAEASPVRNLEKVRSRLSSMNSNPHNRVLVE
KAADVHNTDFEVQEGEAGIPSVSSRANTLAISEGEGALGREATWDDYPNGRWGDARSPAF
GEIDGYGVSLRVSTTEAVKMWSYPVTAADINEVFRKYINGEIQGIPWSEEGLSAESEPIR
EQLGKLNAKGWWTIASQPAVNGLRSDDKVFGWGPKAGFVYQKAFVEFFVPSKDWDTLRER
LANEDEVTYFAGNFAGSTSASDIESVNPVTWGAFNGKEIITPTIIETVSFHAWREEAFSL
WSEWQRIYPPKSATSKLLEGVKKDLWLVNVIHHRFMDKDALWELLLR
>A0A3M0CV52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloplanus aerogenes|TrEMBL
MSLTRSKPADGVANLLSEPRFELMPFDSFEEQMEQLPDGAEIAVTASPQLGLDATVEWSE
KAAARGYEPIPHVAARYVEDRDHLDDIATQLTEAGVTDIFVPGGDREDPVGEFESAYELL
VALDDSGHEFADVGITGYPEGHDFLDDRTLADAMAKKAPYATYITTQLCYDPDAVTAWIE
RIRDRGIDLPIEVGIPGVMKYQRLLNISQKVGVGDSIRFLRKTSGIVGFVRQLVGSRGKY
EPDALVDGLAPYADDPEYAIRGLHIYTFNQVADTEAWRRGRLDG
>A0A3S3F9X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MEKAAIRPSSIDASIEMAPSQVIDSPDLPGLFPSGVRVYITDIGLADTPTLVKAARRVAD
LGYTAVPHMAARRLTTRQALETRVKALAEEAGVRDLLIIGGDVATPAGSFSSSFEVLQTG
FVDKYGITEVGIAGHPEGSRDFGDEAAIAALRMKSAWAERTGAKMRVVTQFGFDADKFIA
WADGLAVSGVDLPIHLGVAGPAKITTLLKYAALCGVGNSLNFLKKRSASLAALATSHSPE
SFVGPIEHHLRAKPESAIAQLHVFPFGGIKNTARWLYERGSWQGLEADDRSSIA
>A0A2T0GCY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus anginosus|TrEMBL
MSSPSPSLSFEVFPPNPAVGNEKIMAALKEMQDLVPHFISVTASNNKFNIEETTVRLADF
IRNDLHIPTIAHLPAVYLTKEMVTETLTALDKVGVHKVLALRGDILPDVEPQKDFVYATD
LIEYIKKEAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYD
FQDKCILAGIEVPIHAGIMPILNRNQVLRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSDTAHRIYQATHTFFDK
>A0A2I4HPZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Juglans regia|TrEMBL
MKVVDKIRAATLGDGGNVVFSFEFFPPKTDDGVDNLFDRMDRMVAHNPSFCDITWGAGGS
TADVTLDIANRMQNIVCVETMMHLTCTNMPVDKIDHALSTIKSNGLQNVLALRGDPPHGQ
GKFVQIEGGFACALDLVKHIRANHGDYFGITVAGYPEAHPDVIGSNGVATLEAYHNDLAY
LKRKVDAGADLIITQLFYDTGVFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCK
TKVPAEITAALEPIKDNEEAVKSYGVHLATEMCKKILAHGIKTLHLYTLNMEKSALAILM
NLGLIEETKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTKGWDQYPHGRWGDSR
NPSYGALADYQFMRPRARDKKLHEEWATPLSNFEDIHEKFKKFCLGKLRSSPWSELDGLQ
PETRIINEQLGKINMKGFLTINSQPAVNGEKSSSPSVGWGGPGGYVYQKAYIELFCSREK
LDGLVDKCKAFPSLTYMAVNKEGSWISNVGQTDVNAVTWGVFPAKEIIQPTVVDPSSFLV
WKDEAFEIWSRGWASLYPEGDTSRKLLEEVQSSYFLVSLVDNDYIHGDLFAVFADI
>A0A6N2I7P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. sk2.1|TrEMBL
MTTLPELLASGTPSFSFEFFPPRTAAGTRTLWEAIRRIEALSPTFVSVTYGAGGTSRDRT
VEVTKRIAAETTLRPVAHLTAVGHSTAELRHIIGQYADAGVRDVLALRGDPPGDPSAPWV
PHPEGFTHAHELVSLVRRSGDFSVGVAAFPERHPRSADWADDIRHFVAKCRAGADYAITQ
MFFRVEDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIGRFAELSNATFPDDLARRLDAAR
DNPADGHRIGVEYATGMADRLLAEGAPGLHYITLNRSTATLEIHRNIQSTRDTRTARNTR
STQSIQSTRSAHALAAAR
>A0A6A6VTH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudovirgaria hyperparasitica|TrEMBL
MEKITDKLAALPKDGTYFSLEFFPPKTQMGFANLQDRLHRMANALHPLFVNVTWGAGGST
ASKSLELAELTQRQLGLTTCLHLTCTNSSRELIDKTLEQAKALGIRNILALRGDPPRSEE
YRDDDQKEDDDSNKDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDESHPEHQDPKNDL
PYLVEKTKAGADFIMTQLFFDTKAWDDYEDMLRKHESGVFKNIPIIPGLMPVQSYQILRR
ITKLSHAKIPTDTMARLDAVKGDDEAVKQVGVDIICEIVEHLKTLGGPTPRGFHFYTLNL
ERSVTQIVERCDLIAEVAEIIKELNGDTGAVVNGDTNGTAPPGVVLTKDRRRLSSTANST
PRNRLVVERPSSSSLASYEALDGEAGVPKDKINTRANALAISEGKDANWDDYPNGRWGDA
RSPAYGEIDGYGPSLHVTRSQALKYWSHPVTKDDISSLFRDHLSGTLEALPWSEDALSPE
TATIRNQLLRLNAKGWWTVASQPAVNGLRSTDSIFGWGPRSGFVYQKPFVEFFLPAADWA
KLQPRLDDASETITYFAGNRAGGWAATDTGFVTAVTWGAFHSKEIVSPTIIEAESFRAWR
EEAFQIWDEWQRIYPPRSASSVLLDGVKNDVWLVNVISHAYVEKEALWEFLAQD
>A0A7V4TXU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Caldatribacterium saccharofermentans|TrEMBL
MSVLRELLERGVFVVTAEVGPPKGVDRESIVKKCAQIRGFVDAVNITDNQTAIVRLSSFA
SCLIVREAGLEPVMQLTCRDRNRIALQSDFLGACALGIENFLCLTGDHQSLGNHPEARSV
FDIDSVQLLGIFRKIRDEGVFANGEKVKGEVRAFLGAGENPFADPLEFRVFRLAKKVEAG
AQFIQTQAVFDLELFSRWMEEVRRLRLHEKVHILAGIIPLKSLQALRYMKDEVPGMVIPA
WVEERMRNARDPKEEGVRIAVETIAALRGIEGVRGVHIMAVAWESIVPEIVRASGLFPRP
GQGGGEGV
>M4ZGH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium oligotrophicum S58|TrEMBL
MTDLASAITDGHSALIRPKISFEFFPPKSEEMDRTLWASIERLAPLEPNFVSVTYGAGGS
TRERTHATIARILKETALLPAAHLTCVGASRGEIDEVVDRYHEVGVRHIVALRGDPPGGI
GTPYSTHAEGYQSSPDLVAGIKKRHPDIEVSVSAYPEKHPESRDFDADIDMLQAKVDAGA
TRAITQVFFDNDVYFRYLDRVRARGIDIPIVPGIMPLHNFKQARGFVSRNGTSVPNWLAE
KFDGLDDDPETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPKSV
NKVAA
>A0A363TNC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobiaceae bacterium|TrEMBL
MTTRPGAAPDSQLAAALRAGRFVITAEISPPVSCRPEDLLAKARPLAGLADAVNVTDGAG
ARAAMAASTAAALLAQHGIEPVLQFTCRDRNRIAIQSDLIGAAACGVRNLLMLRGDDPGA
GDQPDAKGVFDLDSVRLIETAARMRDCGELPTGRKIAGAPRFFIGCADMPIDPPAGWSPT
GLKAKIAAGATFAQTQFCMDAGIVARYARRLADGGVPRDFHLVIGVVPLRSARSARWIRD
NLFGSIIPDGLIARLEGAADAAAEGRRVCVELLQQLAETPGVAGAHIMAPGADEVVPAVI
AEARRGTERIARPPARPPVRSSS
>A0A3S0NKW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobiaceae bacterium|TrEMBL
MTDLATAITDGHAAIIRPKISFEFFPPKTEEMERTLWTSIERLAPLEPSFVSVTYGAGGS
TRERTHATIARILKETALLPAAHLTCVGASRHEIDEVVDRYHEVGVRHIVALRGDPPGGI
GTPYYTHAEGYQSSPELIAGIKKRHPDIEISVSAYPEKHPESRDFDADIDMLKAKVDAGA
TRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARGFVTRAGTTVPDWLAE
KFDGLDDDPETRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPKSA
NKAAA
>A0A3M0EQ03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. PP-F2F-G114-C0414|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGLSFEFFPPKSEKMETQLWEAIRTLEPLAPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATNAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPVDKVAAA
>A0A286F4P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 1222.2|TrEMBL
MLATGRTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSVTYGAGGSTRAGTVKATEQ
IAADTTLTPVAHLTAVSHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWIAHPQGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSPDWDSDVARFVDKCRAGADYAITQMFFQPE
SYLRLRDAVAKAGCETPVIPEVMPVTSVKMLERLPQLSNAAIPNALKERIVTAKDDPAAV
RSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGPHHPSRA
>A0A363TJ81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobiaceae bacterium|TrEMBL
MRAPAVVTASPGDRHDPRAAIASFTGRFSLEATRPKPADVEALKAAVPAGTAVYLSAIPT
RPLAELADAAKLVRSAGFEPVPHLAARAIPSVEALDGLLAATTREAGVRRVLVIGGDTDP
AQGPFHGAVEVIESGLLSRHGVVEIGIAGHPDGHPRIGDHQLDRIILAKIEAAQAIGLKL
HIVTQFCFDAAPILAWLARMRDLGVDAPVRVGLAGPASLTALMGYARRCGVRASTGALAR
NAGLVKNLFGGTAPDAILRALVEKLGEAGDVAPHFFSFGGVPATARWAAAVAAGHIALDR
TEGFSVEAR
>A0A1E5CG16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterovibrio norvegicus FF-454|TrEMBL
MGYSHASHLDSLNQNLSDLNGDINVSFEFFPPSSEAMEQTLWASVQRLKNLQPKFMSVTY
GANSGERDRTHSIVKSIKQETGIEAAPHLTCIDATRDELKIIARDYWNSGIRHIVALRGD
LPEKGQKPEMYASDLVELLKGEADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIIPGILPVSNFKQAARFANMTNVRIPNWMHNQFA
GLDDDPVTRQMVGASQAIDMVRVLSREGVKDFHFYTLNRAELTYAMCHTLGVRPGA
>A0A0S8I411|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium SM23_61|TrEMBL
MKSGSRLEKLLAGGHFVVTGELGPPKGADVAVVEKKANLLKGNVDSINVTDNQTAIVRMS
SIAVSALLIRMGLEPNMQMVCRDRNRIAMQSDIFGAYALGIRNILCLSGDHQKFGNHPTA
KNVFDLDSIQLIQTVKKMRDEHKVLGGDEIEGAPQMFIGAAANPFADPFEYRVVRLAKKA
KAGVDFIQTQCIYDMDKFERFMKMVRDRGLHEKIYMLAGVTPLKSVGMAKYMKEKVAGME
VPDEIIERMRKAGKEKAREEGLNICVEQIQRLRQIPGVHGIHLMAIEWEDAVHGIVERAG
LLPRPEIN
>A0A6L4AKN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MELKTNSRLEKVLKSGQLAVTSECGPPRSSAPEGIIKKGHLIKNHVDSINITDNQTSVTR
LCSLAACVHLKLQGLDPVLQMVVRDRNRIALQSDILGAASFGINNVLCLSGDHQSFGDNP
QAQNVFDLDSMQLVQTVRRMRDEGKFLSGDEIKVPPNMFVGAAANPFADPFKIRVPRLAK
KVAAGAEFIQTQCIYNVDKFELWMQQVRDRGLHEKVFILAGITPMRSVGMAKYLRKSVPG
MDVPEELITRMAGVEKAKQADEGITIAVETIQRLKECKGVAGFHVMAIEWEEKVPEIVER
SGLYPRPTID
>A0A7V5R5A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKAGSNLERVLASGEFAVTGELGPPKNSDPEVVRKKARILRGNVDAVNITDCQTAIVRMS
SIGAGLIAQAEGVEPVIQMTCRDRNRIGMQSDLLAASAMGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMVGSMRDEKKFQCGEEIKGEAPKFFLGAAANPFAYPFEFRAVRLGKK
VRAGADFIQTQIIYNVEKFAKFMEMCRDMGLDKKVAILAGVTPPKSLGMARYMKKFVPGM
DVTDEVIDRMKGAKDKQEEGINICVDIINQVKEIDGVAGVHVMAIEWEEAVAEICERAGL
LPRPTFEESAVVETVTPPVRETVIVKEEKPASGTDAIGAGEEILAKAKEEAASIIAAARA
EADSLKTQAARGPEIEIAGEKFAGVESDAGEHEMNEKERLMALESMKLGLDALKKAYGLN
DDQFEALMKFAGAEAILKKEPPAGSADTVSGSGTPEPVAVDKAVTATVTPAGSVTQQEQE
AQVKEAEAAKIKAEAQAKAEEEAAAKANAEAKAKAEEEAKAKKAAEEKAKTEAKAKAEAE
AKARKAAEEKARAEKEAKERAAEQEKKKDVEKASLDEPVAQSIPGGLDAPKLKTEETPFA
ERAAKVPPTSYKQDYSGTIREVVLGNGDTAVTVGGAEVLPFHLFEGNQPHKPLIAMEVQD
IVPDNWPATLTKYFDDVMDNPVAWAKKCVNEYKADALNIYLIGTDPNGENRPSADAAKDA
AAIIDAVDVPIIVWGCGNNEKDTETLRDVTSLIGNKKVCLAPLEDANYRAIGATAMAFGH
PMVAASPIDVNLAKQLNILLENLGVPLDTVLMDPSIGALGYGIEYTYSVMERIRIAALTQ
KDEKLQVPIICNLGREVWKTKEVGLASDDLLGDQERRGIMMEAMTASCMMMAGGEVLIMR
HPKAISMTKSLIDGLIG
>A0A8I1MZL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus sp|TrEMBL
MTERTFSFEFFPPKTAEGAEKLRATRKQLAQLDPRFFSVTFGAGGSTRDRTLEAVRDIQA
AGSEAAPHLSCIGSTEASIRDILNEYKSQGIRHLVALRGDLPSGSMDVGEFHYANELVAF
IRKETGDWFEIEVAAYPEVHPQARSHTEDLANFKRKVDAGADSAITQYFFNADAYFNFVE
NVHALGVAIPIVPGIMPIGNYIQLARFSDACGAEIPRWLRKKLESYGDDLASIRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPSTTIWQRLGL
>J8HQ25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VD154|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7S0W4P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hemiselmis tepida|TrEMBL
MPKIVDKIVEGKPFYSFEYFPPKTAAGVSNLYERVERMGKLEPLFVDITWGAGGSTSDLT
LELSSNFQQQFCLETQMHLTCTNISKESVAAALKTAKANGIQNILCLRGDPPKGEEKWTA
TEGGFNNAVDLVKFIRAEYGDFFGISVAGYPEGHIDWFKDDPEISKDNYWKDMQYLKDKC
DAGADCIITQLFYDVDIYLQWVKDCRSVGIKVPIIPGIMPINTYGGFDRMVGFCKTKIPK
SVREGLDAVKDNDEAVKEFGVQFVTDMCRRLIQEGAPGLHMYSLNLEKATVDILTNLGLL
KDTSERRSLPWRARIPQEGAANKPLEGVRPIYWANRPRSYMARTLHWDEYPNGRWGDARS
PAFGDLTNYHLGEIHIVDEADRKAEWGAELSSVASVHSVFGDYVEGKKKRLPWCCGVESE
TEAMRSNLAQLNKAGFLTINSQPRVNAAPSEDAVHGWGGPGGHVYQKAYIEFFCAPDVFQ
KLKSTLDGHKSIRYSAINAKGDYESSAKGPVTAVTWGVFPDREVQQPTVVSEDAFKVWKD
EAFGLWNSHWKSLYPAGSASANVIQQIHDTYHLVTVVDNDYVSGNIFAPFAV
>J3E224|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. GM84|TrEMBL
MSLLKSALREKSFVCVMEFVPKPSAQRFAAMQAIMQRGHLCGWPMTLAIGDRVASPLELS
PLDALDSFSTPLPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGERP
VRYLESVAALQIARQACPHWLLGAALNPFKYLEEEGGAQYLKAQKKLAAGADFLILQLGF
DADKHQEALQWMNRQAAPKPLLACLMSLTHGRAAMLEHVAGVTVTPSMRAMLEAEAAVSK
TFAQTRSIDRLALQIIGVKLMGYAGVHLSGVHELEQLLALEARIEHWQARIHSLAQWAPA
WAQSWQMPGLPGVTFHPPLADWRNGQSLVSASAAEKLRYHLLHGFHAALFSRNNWLSKAF
GWVVRRPLWGTAKGARLLHGLERSVKRPLLGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTSLNRCEFGDRECIHSVKYRTAKAVQQTAVLSERLIPCIEVETRHRSSWPQWFEAQPA
RRLSPQPAPRTQPES
>A0A6N9E0L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0677_bin_15|TrEMBL
MHIAEVFRQSQPAISFEFFPPKSEAASESLFHTIQKLIPLKPAYVSVTYGAGGSTRDLTH
DLVVKLHNETNLTIVSHLTCVQSSRDEIFRILQRYDEHSIRNIMALHGDPPSQEPCDPSG
QDFRHAVELVAFIKKHFPHMGIGVAGFPEGHPDTPNRLQEIEYLKAKVDAGADYVCTQLF
FDNRDFYDFCERCQLAGIHVPIIAGIMPITSLQGMKRMAELALGARFPGRLLRALASAKD
DAQAEKIGIHWATEQVLDLLDNKVLGVHLYTLNKSRASLQIYETLGLQRVDMLME
>A0A1M6DF34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium haoranii|TrEMBL
MKVIDHINNANGKTLFSFEIIPPQKGSSIQELYDNIDPLMEFKPPFIDVTTSREEFVYKD
KGNGLLERRITRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSREETEYLLVDCQYLGIDN
VMALRGDAMKGEKYFEPSKGGHTYATDLVKQIKDLNKGKYLHEVIETSNSSDFCIGVAGY
PEKHIEAPSMNYDMKWLKQKVDAGADYIVTQMFFDNQKYFEFVDKARAAGINVPIIPGIK
PIATKRHLQLLPQVFKIDLPEDLIDAVSDCKNNEEVRQVGVEWAITQSRELLEAKVPVLH
YYSMGKSDNIKNIASSIF
>E4TJS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditerrivibrio nitroreducens (strain DSM 19672 / NBRC 101217 / Yu37-1)|TrEMBL
MKICDKLNIKKRVLSFEFFPPKKVENEHILFETLDELTHFNPDFVSITYGAGGSTKDKTL
EWTLKIKNDYKFTVMMHLTCITSDKEEIDQLLDNLKKNGIENILALRGDIPKDGLNYHIS
NDFKYASDLVGFIKKKNFCIGVAGYPEGHLEAVSIDEDIFNLKKKIEAGGDFIITQLFFD
NRLFYRYLELLSKNNINTPVLAGIMPITSFAQVDKFKKMCGVHIPEEFINRIADKDDDYV
FNAGVEYTIKQCEDLLSNGVKGLHFYTLNKSEATKKILNNLRYEVQ
>A0A1Q7RNT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_40CM_2_68_10|TrEMBL
MTRPIAPVLRLEEAFRSGLPVVTCEIATGDGADPDEVLRRVRLVRDHVDAVNVPDNTAGI
VHMAAWAAAALLAREGVDPIMHVTCRDRNRMALQSDLLGAAALGVRNILCLTGDHMVHGD
HPGAKPVFDLDSLQLVSLATVLRHGRYLSGREIRPAPALFPGATENPFAPPYDFRPLRLQ
KKVEAGARFIQTQITFNVKRFAAFMERVRDLGLDRTVPILAGVAPVRSARSARYMRERVP
GMEVPDAIVRRMEQAGSERARREDEGIRICVEIIEQLREVRGLAGFHLLPIHWEEAVAEI
ASRARLTPARASLSAHVEATARDAGSADARRDDSEGALLNRHREHRA
>K9XUW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437)|TrEMBL
MTNRFRSAVAAKEFLITAEVTPPKGGNPARMLEMAEKLKDRVHAVNVTDGSRAVLRMSSL
AASVILLQHGIEPICQIACRDRNCIGLQADLMGAYALGIRNVLALTGDPVKAGDHQKAKS
VFELEAVRLLKVIGQLNNGLDFNDKPLPDEPLDLFAGAAVDPQLKSWSGLQSRFERKLAA
GAQFFQSQMITDFEKLDKFMTQIASISDKPILAGIFLLKSAKNAEFINRYVPGVNIPQSI
IDRLAQASEPLQEGVKIAAEQVKLAQQTCHGVHLMAVKREDLIPQILDLAEVKPLDYSS
>A0A353NET9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MTSISRFPVSIEFFPPKTPEGVEKLRTVRHQLYALKPEFCSVTFGAGGSTQEGTFSTVRD
ILSEGVSAASHFSCIGATHERVREQLATLKAMGVKRLVALRGDLPSGYGTGGEFHYASDL
VAFIRAEMPDDFHIEVAAYPEIHPQARSPESDLKAFAVKVGAGANSAITQYFYNSDAYFR
FVEDADALGVKIPVVPGIMPIASSSQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFG
LDVVTDLCEQLRAGGAPGLHFYSMNQSVATLEICQRLGLAA
>A0A3N5F302|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MKTDSRLEKVLAAGHLAVTSECGPPRGAQPDKVREKGRYLHGIVDAVNVTDNQTAMVRMS
SLAASVLLKQEGLNPLYQLVTRDRNRLAMQADILGAYSLGIDTMLCLSGDHTKFGDHPMA
MNVHDIDSIQLIQMVKAMRDEGIFQGGAEIKGAPKMFIGAAANPFADPFELRVLRLAKKI
AAGADFIQTQCIFNVDKFEKWMEGVCARGLHKKCYILAGVTPIKSLGAARYMKTRVPGMD
VPQEIVDRMASVPKEKQPEEGINICIETIERLKKVEGVAGFHIMAIDWEEKVKEIVERAG
LLPRPQV
>R6ZJS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. CAG:398|TrEMBL
MHVDDIFTKAHAAGKIPVSFEMFPPKGELTLDKAHDAAKKLSAYGPDFISVTCSAGGGGN
FAQTAAIASMLESEFNVSSVAHLTCISLTREGLKERIAQYKAAGVENVLALRGDRPTKDS
PLYGAPSDFSFAAQIIPALIEAGFCVGGAAYPEGHIECECLETSIEHLKLKQDAGASFFV
TQLFFDNEYCYRFLDLAEKSGITVPITCGIMPFVSKQQITRMVLMCGASLPSPVIKLLAK
YDDDPASLAQAGIDYACRQLQDLKEHGVDGLHVYTMNRPSVASAAMQALGR
>A0A1V6Y4E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium nalgiovense|TrEMBL
MRLEQMVTWSTFARILSSSSNHSHCRPIHLKDAMEKKITEKIAALPPDANYFSLEFFPPK
TRMGFANLSARLERMAQALRPLFVTVTWGAGGSTAARSLELAEVCQRQLQLTTVLHLTCT
NMSRKLVDMALDEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNKDFTFAVDLVRYIRQR
HGDYFCVGVAAYPEGHPADNFQDVQDPARDIPSLVEKTQAGADFIMTQLTYDIEAYQKFE
EMLRSHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVTIPPPIAKRMEELKHDDDAVKH
AGVDIVSEIVGGVRDIPSPGPRGFHFYTLNLEKTVSFILEQCDLIPSYSDAGDTAIADDP
ASIPLDFPGRALRRRRASSINSQPHNRVIVDKLSVHESSQDSVHEALADSAGVPAPPPNR
STTLLISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTANTARRLWGHPV
GPKDMSTIFRRHVSGELHMVPWSEGGAEEDGEGLNAETELIRPELLKLIDGRGWWTLASQ
PAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFCSNNDYTNILKPLFAKHGHDKLTWFATN
VKGDFESSLPIQPADMELDDLGSNPESVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAF
RIWDEWRRIYPRGSPTETYLDTTKNDSWLVCVVGQQFGAGNKQGSKEEEDEVKWMWRVLA
GEEA
>A0A1E3IE93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus wingfieldii CBS 7118|TrEMBL
MPPLTSLIAAHDGPFHNYEFFPPRTDAGLVNLLERICRLTSAPLQRPLAVSITWGAGGST
AEKSLELAEQVVKMGVEVVLHLTCTNMAKEKVDLALQKCKDLGIQNILALRGDPPRSEEY
AVTPNVPDFFQHADDLVRYIRAEHGAYFCIGVAGYPTAHPDSETDEDEMKWLKVKCDAGA
DFIVTQLFYDVDGFLAWVKECRAQGIKQTIIPGIMPIQSFGSFRRLVNLTKCPVPSSITS
DLQPISSDDAAVKQYGATLATKMVKQILDSGEIHGVHFCTLNLEKSVRTILDNLDWVERD
QRDSVSSLDRNRFIESDEDARPSGIPINGKTRSYSNSASLSISPSDASHLAQLGLTSVLP
PKSQTHSTATGAPSGPGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKE
WGVPTTLSDLSTLFTSYLQNSPATPTTPFCDLPLSPESQTILPHLLKLNSADKCFWTVGS
QPAVDAAKSEDSVVGWGPRGGYVFQKAFVEFFVRPEEVEGLVRKVDELGKSMITLYASNK
KGDFKTSTDPSAVNAVTWGVFPGQEIVQSTIIEQESFLAWKEEAFDIWTEWAELYPRQSA
ARKLLEGVSEEWWLVSLIHHDYKKEDALWKFLLDA
>A0A525CWK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MSAKKMFDVLYLVELLTPRRDGGEKIPLFLERFQQRYEQALSLGCGISVPDNPMGRTRIG
LPECISQLGLTVDPGKIVMNLNTFHSKTELDTLLDSAAELGINRLLVVRGDGGPELEKLN
PQSIGGKHNIVTTPELVAYINREYEGQFITGVAFNPYKKNDFELAHLQRKIEAGAKFVIT
QPIFDRHEQVDAILDYGVPVVVEAWMSENVALFYKSVGIKQEQSDHSHDPRLVLQKLHQA
YPGSCVYLAMLNFTTDWSVQLPHILSK
>A0A671QC61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus anshuiensis|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPSGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAETFLRF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDALAPETNLLKDELEKVNRRGI
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWVKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFALLDSPRMDKTAQVLWI
>A0A1I0T819|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus pushchinoensis|TrEMBL
MGLLDDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIDAGAEVIQTN
TYGANYVKLARYGLQDDVKQINEAAVRLAKQAAQGRAYVLGTIGGLRSTNKSTISLEEAK
RTFREQLYALLNEGVDGLLLETYYDFEELQTVLSIARKETTLPLIAHVTLHDIGVLQHGI
SLADALHQLEQLGADVVGLNCHLGPYHMLRSLEEVPIPTRAFLSVYPNASLPQYRDGRFV
YETSEQYFEETARAFRDQGVRLIGGCCGTTPKHISAIARALSDRTPVYEKKVKQRHTIVV
QEAERAKEPSLADIARTRRSIIVELDPPKKLGLTTFLEGAKALKEAHIDALTLADNSLAT
PRISNVAVGTIVKQQLGMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRL
EKKIECGAHYFLTQPLYSEKQIEDVYEATKHLATPIYIGIMPLTSARNADFLHHEVPGIT
LSDHIRARMAACANDPVQSTKEGLAIAKALIDAAFDLFQGIYFITPFLRYDMTVELVRYT
HEKERLKKERTVYHG
>A0A2G5IUU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HG99|TrEMBL
MALGSASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPSGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSEDWDLDVAHFVD
KCRAGADYAITQMFFHPESYLRLRDRVVAAGCTTPVIPEVMPVTSVKMLERLPQLSNASI
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQT
>A0A1T4VNY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paradesulfovibrio bizertensis DSM 18034|TrEMBL
MRIKDLIPQKKPFISLEFFPPKKEESLPGFFETVEKLRAVNPLFVSVTYGAGGSTQDKTL
EIVRRLKQDHELEPMAHLTCVGASPERIQRFLNQLEEAEVSNVLALRGDPPQGQERFVPD
SEHFCHASDLVRFIRERHPEMGVAVAGYPDGHPECTTFREDYGYLKNKLAMGGDFVMTQM
FFDNRLYWNFVDIMRSMGVTKPIIPGVLPIMSLQSVKRILQFCGASIPGKFLLDLEAADA
RGGQKAAYEVGMAWARKQVRELLEKGAPGVHLYTLNRAEAVLDIVGSLGSSAEVD
>A0A6J4NHK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Rubrobacteraceae bacterium|TrEMBL
MGLDLREKTDRGVLIGDGAMGTLLAERGVGFGHPYARANVTHPEMVAGIHEEYIRAGAGV
IETNTFSANRFKLEVHELEDRVRDVNEAGARLARKAADSVKADGEKALVLGAMGPLGRPL
CPVGPVTEEEARSVFLEQAEALLEGGVDALVLETFTDLVELRIAHEAVRGLGVPIVAYKT
FVEDGETLSEGLPGRAAREISSLGVDLAGANCTVGPQRMVGIIEGMSAEVGPVAAYPNPG
LPQLVDGKVRFRRDVDHFALYGRKLAEAGARLVGGCCGSTPDHVKALADALRDFRPGKAP
GRGAHLRAVELERPEETPDGPSTELAGKLRTGFAVAVEVDLPRGNDITRVVEAARRLKER
GVDAIDISDGARARLRMHPVAAAKIVQEEAGIEVVAHISCRDRNIIGLQSDFLGAAALGV
KNILAVTGDPTQIGDYPEATGVFDTDSVGLVHVLSKMNRGEDLAGNSIGGPAGFLIGSAF
NPTAEDLDGEIEKLRRKIHAGAHAFWTQPVFEIGALEIALERMGDLDVSLLLGLMPLRSA
RQAEFLHHEVPGVNIPKPIRERLADLSPEDAPKYGVEVAQNLLSKAQPLVNGAYIMPPAS
APDLAGDVVEAIGVRS
>A0A7C1KQQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MNMSFREALESGKFVVTAEVGPPKGTDIEEMIHHIELLKGKVDAINFTDNQSAVMRMNSL
AGCKIALEHGVEPILQMTCRDRNRIGLQSDLLGAYALGVRNLLCMTGDHVSAGDHKGAKP
VYDVESVQLLQIVDSLNNGTDMSGNDLKGKCDFFQGAVVTPEANPLEPQLIKFEKK
>A0A7C1KRM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
PATGEFRYAKDLVEFVGKYNYFSIGVAVYPEGHQEAPSLEADIEYTKMKVDAGADFAITQ
MFFDNRYFFDFLERAQKKGINIPILPGIMPITDLVRIKKFSSFCRTTIPSRIEEMMSGVL
DKPEEMRKIGTELAIRQCKELLDSGVKYLHFYTMNKSEVVSEIIRALRV
>A0A7C8A7A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MKSGSNLERVILSGNPAVTAELGPPMSADGSEIRHKAKLLKGFCDAANITDCQTAVVRIS
SIAGAVIALQEGLEPVMQMTCRDRNRIAIQADLLGAHALGLRNCLCIAGDHQKFSAAGKL
KGHPGAKNVYDVDTCQLVGILKKMRDEGLQQGGDKLEVPPRFFIGASWTPGGEPLDFRPV
NLKKKIDAGADFIQTQGIYDIDIFRSQMEKIRAMGLHERAAILGGIIVPRTAMMLKYMDS
SVAGVSVPKSLIERMAKAKERAGDDKKKAKEYQEEEGIKIAVELIHQVLETPGVKGVHIQ
AIEWESAIEKIVKSAGLYPRPVFE
>A0A7K7KWC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asarcornis scutulata|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVLAGADFIITQLFFRSETFIK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYISGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSNEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A8G2VMP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MAASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVEFIRAETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A842Y671|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon|TrEMBL
MNFTQKLRSGKFVITAEISPPKSPDMSGVLQDAELLKDLVDAVNVTDNQRAMMRMAPVAL
CRKLWEMGIEPVMHVTCRDRNRLALQSDLLAAHAMGISNILAMSGDYPTMGDQPGAKPVY
DLDSVHLLQLIGKMNKGIDFQDSTIDGPTSFIAGAVANPGSRPLDVQLIKLNKKVEAGAG
FIQTQAVFDVGAFVEFMDAIKHLKIPVIAGIIPLRSARSARFMNDKIPGVMISEEIIKRM
EFASEPTAEGLRIAAETIQQIRPVCQGVHIMPIGGHENTRHLLELCGQVRKWKKRRSP
>A0A7C5B2S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSREPQRLKDVLDRGTFAVTVEYNPPKGTNISAVLENAKQLVGRVHGVNVTDNTAAVVRA
GSLPVCRLLYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKD
AKPVYDLDSVQVMQLVQGLNNGKDMAGNKLDGSTAFTIGAAVTPEADLVGPVLAKFEVKV
KAGARFFQTQAVYNPEVFASFMKHVRPFNVKVLAGILLLRNAKMAEFMNANIPGMSVPKE
MIDELKAAGEKAEDVGVDIAVRTIKAVRPHCDGVHIMAIKATHRLAEIITKAELN
>A0A8G4A7X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPRLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQY
FFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGD
DSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A847WAZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Papillibacter sp|TrEMBL
MKITELFGRGEFVVTAEVGPPKGYHIDHLVEEAKEFLKDRVHAVNVTDNQSSVMRLGSLA
TCKVLKDNGLNAIYQLTCRDRNRIALQSDVLSAALLGIDNILCLTGDYTTLGDNPQAKPV
FDLDSVSLLHMVKTLEAGTDLAGNALDGEPPKFAKGAVVSPCSDSVDVQLAKMERKVKAG
AEYFQTQGVYEPEKFIKFMEKAKQFGVPVQLGVIIPKNAGMLRYMNANVAGVHAPDEMIA
ELLKDKEKTKAGITGVEIAARIIRECKDYCQGVHIMALGWESKVPAILDLAGIAPIKK
>A0A6J4PJ80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Rubrobacteraceae bacterium|TrEMBL
MSDVGKRATLKGPAWFRFEMMPTEGAAEQAAYLPEGAKVAVSCSPAKGVEGTLALSKELS
GRGFRVVPHVSARLVEDEAHLEQILRRLGGVGVKDIFVVGGDTKEPAGPFEDAFALLSAM
ADVGHGFAHVGVTGYPEGHPTIADGDLRRALRDKLPFATYVVTQMCFDPEAILGWVAGIR
REGIELPVYVGIPGAVERRKLLRISLRIGVGDSVRFLAKHANIVASLFKPGYNPDTLVDE
LAPYIGDRDHNIAGFHVYTFNQVESTEKWRQRAPSLSGVAAG
>A0A8G7TM92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas aeruginosa|TrEMBL
MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDR
TLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMAS
GELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGAITQYFFN
ADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSR
SIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR
>A0A1E4EMN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. SCN 68-21|TrEMBL
MTDATPPDFARWQPSYDTPPPGHVSSSRLERVLRQGHFAVTAELNPPDSADPADVFTAAR
PLAEVADAINATDASGANCHMSSIGISALLTRAGYGTVYQISCRDRNRIAIQGDVLGAAA
MGVRNVLCLTGDGVGVGDQPGARPVFDLDSISLLRTIRTMRDDGVFLSGRRITSPPRMFL
GAAENPCIAPLDWRPDRLAKKVEAGADFIQTNYIFDIPVFERFMARVRDLGLDRRVFILA
GVGPLASGRAARWMRSNVPGIHIPDAVIDRLDRAADPGEEGKRLCIELIQQIRQIAGVSG
VHVMAYRREHLVREIIAQSGVCRDRARA
>A0A662RWJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcinales archaeon|TrEMBL
MAAKEAYSRFMEELLSGKFVWTGELEPGKDIKESLEAARELKGLVTACNVTDNPQSFASI
SSLAAAHVIQRETGMECIYQLRCSDRNRLALMSEVMGAGILGLKNVLALTGDYVMLGDTP
AAKPVYDLDSTTLTYMIHRLVHEGKDIAGNDVPNPPKMHVGVAAGPGVDPIEPEMYKLKR
KVKAGAEFVQTQVIYKTEVVDRFFKWVKELQIDVPILIGIFPAKSYGAAKFFDENVTGVD
VPTEFLAELEQTVKIKDKEKRREETDRINIEYFTKFLEHLKGTPAAGCHIMAVGYPRIIP
ELKKIVE
>A0A7Y8HN48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MSQEPRRLKEVLDSGQFAVTIEYNPPKGTNISGVLENAKQLVGRVHGVNVTDNTAAIVRA
GSLPVCRLLYELGHDPVMQMTCRDRNRIAMQSDLMGASMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGQDFVGNKLDGATQFTIGAAVTPEADPLGPMLAKFEVKV
KAGAQFFQTQAIYHPEQFASFMKAVRPFKVKVLAGILVLRNAKMAEFMNANIPGVSVPQE
MIDELRAAGPERAEDVGVDIAVRTIKAVQPYCDGVHIMAIKATHRLADIITKAEVG
>A0A328FCB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacter hydrogenophilus|TrEMBL
MRVTQLYKDKQPAISFEFFPFRDDKTQASFNNTIDALSPLSPDYFSVTFGAGGSTRDGSY
ATAKILVDKNFPTVAYIAGFGLAPDEVRDILDKYKALGIETIFVIRGDQPKDADFKPHPD
SFAYACDLIKFIKDNYDFTLGCAGYPEGHVQAESLEADIKYLKMKQDAGAQYVVAQFFYD
NEFYFSYVNKCRDAGVTIPIIPGIMPVYTLKLINILTSVCGASIPAAMQARIDAVDKGDK
DAVLNLGIDYAAEQCKDLLAKGVPGLHIYTMNRSRSTKAIVEALKKENLI
>A0A022IPU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. 1000160|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GQGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A5N8YC32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium AC-647-N09_OGT_505m|TrEMBL
MSGIPLGRNSRGQCSGPFMEPTMAKITDICSESRDGPVIICDFSPPRGADPALLQGALSV
DADFLCVAYSPGKSVRVDSVIAAYVIKEQMERDVIFTIATRDMNKLALQSHLLGASQLGL
HNVIVVGGDGFTERDLTVVKDVSDFTSTGLITAIKAMNLGTDYKGLKLRSVTDFCVGATI
DLGRDIEREARLTYRKVLAGADFFITQPVYHLDQVERFQESYESVAWERLSMPIFLGLQI
LDAKGLIFGEVPESIKKDLEHGREGTDIAIDLLHQFVAGGITNIYLVPPIFRGGLRDYEA
TKRVLEGFK
>E8K1C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus infantis ATCC 700779|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAQYIHQATHALFNHQPVK
>A0A830E5G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobellus salinus|TrEMBL
MSLGAQRGAETSTADGAEYLLTNARFELMPFDSFEDEIQHLPDGASVAITTSPKLGIEKT
VERSEEAAAQGYDVIPHIAARYIEGPEQLEEIARRLTEAGVTDIFVPGGDKEDPVGEFES
AYDLLVALDDIDYEFDEVGITGYPEGHDFISEDELTESMEKKAPYATYIVTQLCYDSEAI
LEWIEEIRARGVDLPVEIGIPGVMKYEKLLKISRKVGVGDSVKFLRKTTGLVGFVKQFVG
SRGRYRPDDLIDGLGPYVGDDTYNIHGLHIYTFNQTPDLEGWRRGRLED
>A0A533VHA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MTVTYELNPPKVIQDTVLSHQQLQESVNKLKTKALEVSNVCNSIHVTDSVLGIPRISPIT
IGVFIRNSNDGIDLSASVRVRDRNLTSLTQTICDAILLDLNAVLILKGDPPPAGPKDSKL
VPSEVVKQFNEQGFGKKIDLFLSLPSNPNFEKIHKKIEAQPKGFVTQVISSLDQIIKIVD
KLKPQGFRIIPCILLPSEKNLQSAKRLNLDWSNYSNDVVGFIKEAHKISGNVLISSPNDF
KRALEILKKLT
>A0A6G7C357|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. DR205|TrEMBL
MKITDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTEGGHAFATDLLEQVADMNKGKYLHEDIITSEKTDFCIGVAGY
PEKHFESPNFNTDFKYLKQKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVASCKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLV
>R8RKQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus HuB4-4|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A4R4DD55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracraurococcus sp. NE82|TrEMBL
MDQSPTKPAERPSSPTPHGTLGRWLTGPRVDGLPQLAALPPPALSFEFFPPRTEALEAQL
WSCIRRLEPLAPRFVSVTYGAGGTTQARTHATVARIVRETSLTPAAHLTCVGASRGEVDD
VARAYWDAGVRHIVALRGDPPAGAERYEPHPQGYAFAADLVEGLRRVAPFEVSVAAYPEV
HPTALSADHDLDNLKRKIDAGATRAITQYFFDSDIFLRFLDRCLAAGITVPIVPGIMPVS
NFTQMKKFSGMCGAGVPDWMGRLFEGLEDDVETRRMVAAVVAAEQVRLLQANGVDEFHFY
TLNRPDLVYAIAHILGARPRQPAGQA
>A0A0E3V1N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter duraquae|TrEMBL
MELSVEFFPPKTPEGENKLHLVRERFSEMLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRDNVREMLKQYQALGIKRIVALRGDLPSGMGQYGEFHHANELVEFIR
TETGDWFHIDVAAYPECHPQAKSPATDVDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YELGVTQPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDTASIRAFGEEVVT
DLCDQLLVAGAPGLHFYSLNQADAVLAIADNLSLNK
>A0A3D3SCB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetaceae bacterium|TrEMBL
SGRCLSIEMVPPPRGGDLESIMAAMEAILPHDPSFVSVTDHPGGKAWADSADGPRRVALR
TKPGTLGTAVALRDAFGITTVPHIVGGMADRLDVEDLLIDLHYANFRDIFVVMGDDRYAP
ASMGGNVGGRGAGTDGYEHASDIVKHIAMLNRGKYTPPAEGKPTDFTIGVAAYPQKHFAA
PNPDTDFRHLVEKIRAGAKFVITQMVFEAEPYVDLVRRLRELGLDLPVLPGIKPLFKASS
LDMIPRTFFVDIPQPLVKALREARSPEEEKAAGIAWTTKLCGELLDAGAPGLHFFTMGRG
AGTRWVLDALYGPKGT
>A0A1X7FBW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trinickia caryophylli|TrEMBL
MKPIEISFEFFPPKTPEGVEKLRATRAQLALFKPKFVSVTFGAGGSTQQGTLDTVLEMAA
DGLEAAPHLSCIGSSKESLRAILERYRSHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRAEYGDWFRIEVAGYPEYHPQSRSPKLDLENFARKVKAGADAAITQYFYNADAYFRFVD
DARKLGVDVPIVPGIMPITNYSQLMRFSDMCGAEVPRWIARRLESFGDDREAIRAFGLDV
VTQLCERLVREGAPGLHFYTLNAATASKAICERLGYARGV
>V9WJY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter gallaeciensis DSM 26640|TrEMBL
MTTPDISFEFFPPQSLEASFRLWDTVQTLAPLAPRFVSVTYGAGGTTRDLTREAVATLHN
ASGLNVAAHLTCVNATKAETMTIADQFAEAGVREIVALRGDPPKGSAGFEPHPEGYANSV
ELIAALAERDQFSIRVGAYPDRHPEATSARADVEWLKRKLDAGADEALTQFFFEADTFLR
FRDDCAKAGIDTSRITPGILPIENWKGARNFAKRCGTTIPAWIDDAFDKAIRDGREDLLA
TALCTELCSDLMDNGVDKLHFYTLNRPELTRDVCFALGITPDVSLENVA
>A0A7Y0W0K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. WS 5532|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYRDDVKSIQAFG
EQVITQMCEQLLQGGAPGLHFYTLNQTEPSLAIWNNLKLPR
>A0A847DF38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatiglans sp|TrEMBL
MTVKSNLKRVLEEGKFAVTAECGPPKGADPDVIMEKAALLKGIVDAVNVTDNQTAIVRMS
SLAACSLLIKAGIEPVFQVTVRDRNRIALQSDILGAAAIGINNVLCLSGDHQIFGNEPQS
MGVFDIDSIQLLNVVRNMRDRGKLSGGDELTKSPDLFIGAAANPFADPLDFRVIRLAKKI
AAGADFIQTQCIFNMDRFEKWLQMAIDRGFTEKTFILGGVSPLKSAGMAKYMNNNVAGMD
VPESVIKRMEGVPKDKQKEEGIKICVETIQRLKGLKGIKGVHIMAIEWEEAVNEIVKRAG
LLPRP
>A0A1G2Z4F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RBG_13_60_9|TrEMBL
MTRASLKEKLTKRAGFVILAELTGGPGFSLDPIERFLRAYQEKPGAVPGQFDSAAIALPQ
SPGGVANIEPTSVIHSMQAKGLLDRLDVVPHVTCKDMNADAVFSSLMSLRKAGIESVLAL
TGDKPTRAAGVFELESLGLLRLIGRINRDSYIQARPQALHAVHQFFPGAAVSPFKYTEAS
QMQQYYKMEKKIACGAEFLITQVGWDWRKSLELFTYMKETGLTVPVIGNVYLLSTLTPAP
RLMHDLKLPGCYVSDELLAKIRSERVDDHSERAAQQVAMYRALGAAGVDIGGVHDFDMFT
RILQRAAEIGPNWEQFKDNLHWPAKEAFYLYDESGQRARLMTPYPTFKKRFFDFSHRAFL
DPRYTGFRAFRKTMAILGAGKGTGALYKLFNSSEKAFKYLAFECEECGDCFLPENFGLCT
VGGCEKGMDNAPCGDATVDGRCGNNLERICIGERIYEAAASEDKAQSRASVPALQEKSRE
DARPTKRQRTEDRGRQRLRTIVNTPRNPALQHTSSIINYLFGKDHTMTTPIISIGESIHA
SIPKTGKIMKELHDLGRDAYSRPSAQLEYIKALIESQADEGADYIAVNLDAFGEDNPRQA
VDMMVEYVRLVRKWGRGVPICLDSSNDDVLIAGLKEWYKVSEAGDRRPEAGGQRLQPTAC
GLQPLLNSVKVYTMDKILPLKRDYDFSFIGLLVSEDKPMGPGGYHSVDELYGLAKRIFER
AVGHYGFRPNQIFFDSTVFPLAIDMPMEPGVPGYTYRTFETIKKIRSDPQMKGVHCSLGI
SNSVRDLPARKIGVCRAYVAKAMEYGLDAGIVNTAHQYGSVEAPPELLELVDAYAKLDGS
LERTGKAMELMAQFCRENRKAS
>A0A2A4WHP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piscirickettsiaceae bacterium|TrEMBL
MALEPHQPISFEFFPPKTEEGRVKLLIVSKKLGQLDPAYFSVTFGAGGSTQQGTIDTVLD
IKKQGFSAAPHLSCVGSTKENIRAILANYKENGVDRIVALRGDIPSGTLDIGEFRYANEL
VGFIREETGDHFHIEVAAYPEIHPQAKNARTDLKNFKQKVDAGANGAITQYFFNFEAYIR
FVEDCDKMGINVPIVPGIMPITNYSQLARFSDMCGAEIPRWITKRLEGFGDDRESIKAFG
ADVVSELCQSLLDYGCPGLHFYSMNQAEASLVICRNLGVENA
>A0A2D5Y831|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MSIGRSLKERFAEDKPLFSVEFFPPKDEAGGLRMLKTAALIQPYRPDFVSITYGAGGGTR
STTLRYAKLLQQEHGFEVMPHLTCVGHTRDELLEILEEFAQAGFRNIMALRGDPPKGETT
FKPVAGGXSYGSXLVXXIRXNFPEFGIGVGGYPEKHPEADSXGIDLKNLKTKVDAGADFI
TTQLFFNNSVYHDFVERCRKXGIEIPVLPGLLPVLSIGQVRRFCAMCEAGLPSQLERNLE
NTDETGQPVVGAKWALEQIKDLLSRGAPGYHLYALNKSQSTLQILEGLGKS
>A0A1G3A3H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RBG_16_55_9|TrEMBL
MKPDSRLASCIDKQEFIITAEYLPRAHTSPSVNEGVVKALNGKIQAVNVADNPYGIIASS
LSGSLALSRSGVEPVYQIVTRDRNRIALQSDLLGAASLGIKNVLCLSGYHQALTGCPESA
NVYDIDSIQLVAAVSRMRDEGVLLDGTKIEGDFAMLAGAAANPYLRPVELNMLRLAKKIE
AGASFIQTQAVFDVQGFAEWLDAARREGLTGKAVILAGVLPLSDAAEAEELRERYTDFHI
PDAIIDRMRKAGDQEAQRKEGLAIAAETIRQIRTLDGVRGVHILSGGKETSVPELIAASG
L
>A0A2P5N1P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas sp|TrEMBL
MNISFEIVPRSLEAFEQQYAFVQTLDKGINILNVPDIQRFDTRSWELAAQIDRQRYRFIP
HFRAIDFKISSGELFRIIDDYQLDSVLLVTGDPPEGLKRSFYNTDVVDLIKAVRQHFPNL
TIYAGFDPHRSGVQAECDYIQRKADAGATGFFSQPFYDQRMIEIYAEQMTGLETYIGISP
ITTKASMNYWEVKNQVKFPLNFRPDYEWSIEFANQVIATAANNGWHVYFMPIRIDLGRYF
GGIKMDV
>A0A558A3F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis acidiphila|TrEMBL
MTNPREESARRRRSRLAELVRDTSYEVMPFKNTERDVLAAVPVDVPLTVTVTEAKGIDTT
LALTERLLGHGYRVAPHLPARLFVDQQHVADVVARLTEAGVKSVFVIGGDAPDPAGEFTD
AYSLLRAMEEAGHSFEVGIGGYPEGHGSIPQEAIDLALKQKAPMARRVITQICFDATRTA
SWAEGIATAGIELPVYVGMPGPVNRQKLMRISAGIGLGQSARFLQKQQSMLWRFLLPGGY
DPTKLARRLGTALPKFRTNVRGLHIFTFNELRGTEQWRQKLLAALSEKEDDA
>A0A2E0PNV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MKEGLSIKSFFEKNKSLFSVEFFPPKDEAGGERMLKTASLIQPHNPDFVSITYGAGGGTR
STTMRYAKMLKDEHGFEVMPHLTCVGHTKDELLEILEDFANAGFCNIMALRGDPLKGESE
FRPVTDGFSYASELVSLIRENFPHFGIGVGGYPEKHPEASDQKTDLKNLKTKVDAGADFI
TTQLFFDNQAYLDFVRNCKETGISVPVLPGLLPVLSIGQVRRFCSMCEAQLPNRLEQDLE
AEAKENQPKIGARWALGQVKGLLDAGAPGFHLYALNQSTSTLAILEGIDRT
>A0A558A988|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis acidiphila|TrEMBL
MKSVVERLRGDAPVFSVEFFPPRDAADEAVLWRSIRELESLDPAYMSITYGAGGSSRDGT
IRNIARAATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGDWV
AHPQGLNYAEELVSLVRSLGDFCVGVSAFPYGHPRSPDLDTDTRYLVRKFNAGAEFGIAQ
LFFQPEDFLRLRDRVAAAGCDAMLIPGVMPLTTPRTLKTTIKLSGAPCPQSLLDRLEPLE
NDPKAFRAEGLDVVTELCERLIAEGVPDLHFYTFNRSKATREVVQRLGLVPARAQNPVAA
GR
>R6RVK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides finegoldii CAG:203|TrEMBL
MKVIDLIHNNKKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELVKEALKCKTDAEAEQVGIEWCVTQCKELMSHGVPSIHF
YSIGAVDSIKKVAKIIY
>A0A0U3TJ57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cepacia JBK9|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAATATRTICERLVV
>A0A8E1S044|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea dispersa|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEATLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRAIARDYWNNGIRHIVALRGD
LPPGGGKPDMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMYAMFD
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPTLAA
>A0A7U4JF38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium fabacearum (strain H13-3)|TrEMBL
MHDISTSPAIAASIEASPAQVLGPASLAGLFPQGVRVYLTDTGQASQDRLVDAAKHLRDL
GYTPVPHLAARRISSGVEFEEQVKRLAGEAGVSDVLVVGGGVATPAGPFTSSMDMLSTGI
FDRCGINQIAIAGHPEGSPDFSEETATAALKLKYDFAERSDAAMRIVTQFGFDPARFIAW
AEGLAASGIDLPVHIGVSGPARITTLLKYAALCGVGNSIAYLKKNALSLTTLAKGHSPES
VVGPIERHWQANPAGPIRQIHVFPFGGLQNSADWLAGRGSWQIGDADFSAKRGTVAI
>D6D6L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides xylanisolvens XB1A|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAAGINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A7Y2GJQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
MSNSSVTPDPQVVRAGYERLVENFIYELIPMKSAPDKIGELPPGSTVSVTCSPAHGIGET
LELAKQIAAAGHRPIPHLAARTVTSRHELRDAIGILDDLGLTEVFVIAGDAEQPRGPWFD
SIEFLTDLLEMAPNLQAVGFGSYPDGHPAIDAERLSAALLAKQALLAEAGVAAHTSTQMC
FDPQQLISWLASVRRAGFTAPVRLGVPGAIDRMKLMKMGMRLGVGASLSYLRKNRSSLTK
MFISTGYDPGELIGPMSAHAEALGIEGVHCFTFNNVAATVEWHAGQRRALADEPA
>A0A4V3MF92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium M00.F.Ca.ET.180.01.1.1|TrEMBL
MSQLINKLKQNILVADGAMGTILYSDGLDTCPEAYNLTHPDKIERIHRSYIESGADIIQT
NTYGANFEKLKVFGLEHKVKEIHKAAVQIAKKAANDETFILGTVGGFRGVKQEDLGLEAI
QYHTEIQVDTLIEEGVDGLLFETYYDLEELTNIIQATKRKHRIPIIAQLTALNTNYLRDG
TEINTALQRVVDSGADIVGLNCHHGPHHMQQSFSHIELPDNAYLSCYPNASLLDIENSRF
KYSDNAEYFGKVAEQLIQEGVRIIGGCCGTTPEHIQYIKSSVANLKPVSTKNVIPIKKYN
SPSHVNTQQQNLTTKVKARPTIIVELDTPKHLDTETFFRNIKKLDDAQIDAVTLADNSLA
TVRISNVAAASIIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLLNVNEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNEGINTDGDALKTKTNFNIAGAFDPNVRKLEGSVKR
AEKKIESGTHYFITQPVYSTEKIEEIYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEDILEQFEAVKDDKEKTKALSLKLSKELIDTVHKYFNGLYLITPFQKVDYTLALASY
SQSITSSKQEAIL
>A0A7D4X9A2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. FDAARGOS_724|TrEMBL
MFKQIPISFEFFPTKTDAGAEKLKTVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDKDIQHFADKVNAGANAALTQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKFCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A1H8KB38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. OK095|TrEMBL
MTDLTIPAHSDGQDGHLKRPAISFEFFPPKTEDMERNLWETINRLAPLDPKFVSVTYGAG
GSTRERTHSTISRILTETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTPYASHPDGYQTSDALVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRAGTSVPDWF
AAKFDGLDDDAETRKLVAATVAAGQVQKLAKNGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>F4C4Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. (strain 21)|TrEMBL
MKITEHISNAKNKTLISFELLPPIKGQSIQGIFNTIDPLMEFNPPFIDVTYLREDYIYKQ
HPNGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARKSESSFVPTPGGHAYASDLLQHVVNMNNGQYLHDYMDNTEKTDFCIGVAGY
PEKHFEAPNLETDFQYLKQKVDLGANFIVTQMFFDVNKYKAFVDKCRANDINIPIIPGLK
PLTTSKQLTSLPKVFHLDIPLELSKAVQACKSEKEVKDVGIEWMIQQCKDLIKMGAPVLH
FYTMGNPEPTKRIIQGVF
>A0A2G5PUU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium sp. N5G01|TrEMBL
MHSPMFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVS
EYGIPSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFEHASDLAA
YIRQQRPGMKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KARAAGVDAPIEAGIMPVMNAKSVLNMSSKCQSKIPEKLSIMLDKWGSDKALLKEAGIAY
ASEQICDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A3C1EAV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erysipelotrichaceae bacterium|TrEMBL
HITCRDRNLNAIKALMMGLSSEGVHQVLFVTGDPLPQDAKAEVKAVYNFNSRKLMQRIGD
MEEVSQRFAMFGALNVNASSFEQQLALAKEKERNGAIGFLTQPILSQRALDNLKRARSEL
NGFLFAGIYPVVSYKNAMFLENEIHGMHIDEQIIARYQGLDRAQAQQLAADISVRIMKEC
RPWCDGLNLMTPFQRLGLMEQLIKEARCILNEVPGR
>D7B1U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / CIP 107115 / JCM 7437 / KCTC 9190 / NBRC 14626 / NCTC 10488 / NRRL B-5397 / IMRU 509)|TrEMBL
MAPRGPAPRPRHIRELLDAGEPMFSFEFFPPRTPQAQERLWRAIREIEALGPAFVSVTYG
AGGSTRGLTVETTERIATDTTLLPVAHMTLVDHSVAELRHLVGRLADAGVSNMLAVRGDP
PGDPDGEWVRHPQGLTYAEELVRLIKDSGDFCVGVAAFPYKHPRSADVETDTDHFVRKCE
AGADYAITQMFFDPEDYLRLRDRVAARGCEVPIIPEVFPVVRTSFIPRSEQLSGAPFPAD
LAEKFASFGDDDESVRAFGIEHAQRMCERLLAEGAPGIHFITSNRSTATRQIYREISGHR
SPSGGAGRP
>A0A1M6G9Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parasporobacterium paucivorans DSM 15970|TrEMBL
MKIASVLKERMSFSFEVFPPKTDKGMENLKGAFQHYYKYKPDFISCTYGAGGSNTGRNIE
VCQTLKGDGRTEVMTHFTCIGNSKEKIKSELDNYRSFGIENILAMRGDFQPGMDRTNGDF
SNADALIKFVKTQFPEFCISAACYPEKHILAPSFTSDIAHLRTKQDNGAEFLMSQLCHDV
EAYKAFADRIRKAGVHLPIVVGVMPALDKDAIIRMTVSNGCSVPRDLAAVIGKYGDNPTE
FKKAGIEYTVNQIHRYMEAGINGLHLYALNKFEDLETILDASGIRKDI
>A0A3N2DHP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinobacterium caligoides|TrEMBL
MSKRFSLEFFPPKTIAGREKLRGTLQQLDKLKPDFYSVTYGAGGSTRDNTIGVIEEMREA
GIDVAPHLSFGGDSDTEMSELLDQYRRLGVKRLVALRGDIPSGTGISRLVYANELVEFIR
RHSGNHFEIEVAAYPEIHPEAEHYDSDIDFLKQKFRCGADSAITQYFFNADAYFYFMERC
QQAGIEQPIYPGVMPITNFSNLCRFSANCGAEIPRWLKQRVDSFGDDQQAIEEWGVEFIS
RLSERLLAGGAPGIHFYTMNQVEPTRSIWNNLGLSR
>A0A495WBS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azonexus fungiphilus|TrEMBL
MNTNISIEFFPPQTPEGVEKLRATRAELAKLKPEFFSVTYGAGGSTRERTFAIVREIASE
GFDAAPHLSCIGSTRESIREILAEFKATGVRRIVALRGDLPSGMAEAGEFRYANELVEFI
RAETGSHFSLEVAAYPEWHPQARSPKDDLDAFARKVKAGANSAITQYFYNADAYFHFVDE
ARALGVDIPIVPGIMPIVGFTKLARFSDACGADLPRWMRKKFESFGDDSDSIRAFGLDLV
TELCERLLKGGAPGLHFYSMNQSALTTEICRRLG
>A0A520XPB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiales bacterium|TrEMBL
HLTCVGSLKSEIDEIAKDYWDAGVRHIVALRGDPETGIGNAYKPIPGGYNYGSDLVAGLK
NVAPFEVSVGAYPELHPESQNWDAELDNLKRKIDAGADRAITQFFFETDTFLRFQDRVLD
AGIKIPIVPGLMLQPNFKGLKRMSEMCAIAVPNWLEALYADLEDDPQARLLVTATTVADL
ASNLRDQGIQDLHFYTLNKADLAFSVCKILGFQSQKKAVA
>A0A6J4FCI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum sp. SS-4|TrEMBL
MTELPIAAASNNPVSVSFEFFPPKTDKMQEALWDCVKRLEPLSPRFVSVTYGAGGTTRER
THDTVVRIARETSLKPAAHLTCVGHSRGEVDDIARRYWDEGIRHIVALRGDMPDGQPYAA
HPQGYAYAVDLVKGLKRIADFEVSVAAYPEKHPDAPSAGFDLDNLKRKVDAGASRAVSQY
FFEPAVFLDFQERAARAGISVPVVPGILPVTNFAQVQKFSAACGASVPAWMARLFEGLDD
DPETRRLVAATVAAEQCRILAAEGVEQFHFYTLNRADLAYAISHILGVRPRG
>A0A834JJ90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vespula germanica|TrEMBL
MRSFVAGIKVTLEGKINNDNDCKITKYCRLNRRTNELVDLQQVINEKINKKEVFYSFELF
PMKGSSDIYKRFFAEMDKYSPLFYALTWHTKGLINSYLSLDIVEQFPSHTLLHVAAKGLK
RSNVEMILKRAYHLGIRSIFALQGDSILEDGDFPHAIDLVKFIRSSFGKKFSICVAGYPD
MHPLSPNKDFDLFYLKAKVDAGADFIITQIFFESDTFINFVNDCKNIGITIPIIPGIFPI
PEYKCLQRMTNICRLHIPKKIVDRLETIKDDDEAVKNFGIEFAIDLIKDILESRASYGFH
LFTLNKIPMAQNICNQLNLTYQLHSEQL
>A0A5K4Y7A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MNSLKQALDEKRFACVLEVIPQQSPARLAALEPIMRRGQLAGWPLLPAFADRVGPHADLS
PLQGAGALGDPASSLLHFSGKDRERADLLRQMAAMGARGLKQLLLLSGDRLPGHDPGRAP
VRYLESVPALQIAREHGPDWLLGAALNPFKYREEEGGAQYLKARKKLLAGADFLTLQLGF
DAAKHIEAQAWMRTQPGAKPMLACVMNLSERRADVLQAVPGIVITESMRQLLGKEREVSH
AYASARSLARLALQIVGLQWMGYAGVHLSGVHTLDELLLLEQAIIEQRGKVTSLADWSER
WQAGWRLPGAPEVRFTPGIDAWTLGQADVVATRRERLRYALLATVHEQFFDRAGWFSRAF
GWSVTRPMWQAGVAANALRAVERTIKRPLVGCDTCGSCRLQDTLYVCPETCPKGLANGPC
GGTRLNRCEFGDRECVHSVKYRIAKSTNQLPALAQTLIPGVEAQDRHRSSWPEWFKQEDS
APGS
>S5AGV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas mediterranea 615|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASREELKQIAKDYWDSGIRRIVALRGDLP
PGLEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDIDLVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGA
>A0A5K4ZG94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLREILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVAKVNAGANAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAELGDDKASIRAF
GVDVVTELCQNLLDNGAPGLHFYTLNHAEAPLAVWKELSV
>A0A7C5U272|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidilobales archaeon|TrEMBL
MIIGGSISRSSTKDLCYILLSTTFLSSHDKNIKNLRLIDYSVYILSCPKKMINGPCGGYN
RSRCEDPRLGCVWIKAFENLKKYGREKDLFKLKLDSMFKIRDHKPIKRDIREKLKIKDRI
YLIYEYVASRDIDPRKLEKDLDHIFSTYDAIDFVQNPGGRPLPDPLSLAVFTKKIYPHKH
VGFQITGRDYDRDAITSIVASAIVFNIDSIIATTGDLKFHKEKTYGVWDLDSSRIIYLIR
LISDLGRDYSGRKILEKPREILVGASLNPYLDPIEPEIYKLNIKKHAGADFFVTQPIFEP
ETYTRIMRLYKDLLNENDIPEIIPGISIISDIRIASFLIERSGVKPPSKILEALKREDFS
LIKETNIEFISDLVRKICVNHEKKIFYISTFGDIDMALEIGGSIKKMNC
>A0A6A3C0R8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hibiscus syriacus|TrEMBL
MKVIEKIQSLQQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALENIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDAIGDNGVATPEAYQSDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMTGFCKT
KIPDEVIAALEPIKDNDEAVKAYGIHLGTEMCRKIIANGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANIFRVKEDVRPIFWANRPKSYISRTIGWDQYPQGRWGDSQN
PSYGVLSDHQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSYCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSREKL
DALVKKSESFSTLTYVAVNKDGDLVSNIGVTSVNAVTWGVFPAKEIIQPTVVDPASFMVW
KDEAFEIWARSWSALYPEGDPSRKLLEQIQKSYYLVSLVDNNYMDGNIFGVFEHL
>A0A1L7XBR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phialocephala subalpina|TrEMBL
MHIKEMLAGAEQSGQPTFSFEFFPPKTAQGVQNLYERMDRMHAFGPSFIDITWGAGGRLA
QLTCEMVSVAQAQYGLETCMHLTCTDMGEEKVNEALNNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVKHIRQRYGNHFDIGVAGYPEGCDDQKDEEILLDHLKEKVDAGATF
IVTQMFYDADNFVRWVGRVRAKGITIPIIPGIMPISTYASFLRRANHMGCKVPPEWSAAL
EDVKNDDAAVRSIGTGLVAELCRKILKAGIHHLHFYTMNLAQATRMVLEELDMMPSEHRP
LKQALPWRQSLGLGRRDEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDARSPAFGELDA
YDIGLKGSNEQNRKLWGEPKTIMDIANIFVKYLEKGVDSLPWSEAPISSEADSIKADLIR
LNQRGFLTINSQPAVNGAKSTDPVYGWGPHKGYVYQKAYLELLVPPNLIDELIARIERDP
EMTYYAVSKSEAATLKTNSPEGPNAVTWGVFPGKEIVQPTIVERISFLAWKDEAFRLGTD
WARCYSSLSPSRHLIDYMMGTWFLVNIVHNDFHQSHGLFPLFDGLKVEDLDKEFEVIATN
GEHSETNGVNGVENTPLTNGA
>A0A316JL71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. XM-24|TrEMBL
MRLQQALEAGQFALTAEVMPPRGGEIKRTLEHAALLKDWVHAVNVTDGSRAVMRMSSLAV
CRLLLDAGVEPVWQQACRDRNRIGLQADLLGAHALGIRNILCLTGDPVRAGDQPQARPVN
ELESVRLLKQVAAFNRGEDPVDGSLPDGPTDLFAGAAADPQSPSWSGLNSRIRRKQQAGA
RFVQTQMVMDEDCLKRFVDEITAPLGLPVLAGVFLLKSAKNAAFINRVVPGACIPQAIID
RLAAASNPADEGITIAAEQVRRYAQTCQGVHLMAVKAEERIPLILERAGFSSRC
>G0WG35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639)|TrEMBL
MKVTEKLEASHKSSSKTTFSFEYFVPKTSQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSQLSTDLISTAQSVLGLETCMHLTCTNMPIEEIDSALKKAYDSGCQNILALRGDPPIN
SNKWEACEGGFNYAKDLIKYIRLKYGDYFDIGVAGYPEGHPEEKDIELNFKYLKEKIDAG
GNFIITQMFYDVDNFIDWCDKVRAYGIDVPIIPGIMPITTYGAFLRRAQWGEINIPQDFL
DKLDPIKDDDELVREMGTELIVGMCQKLIDSGHVKHLHIYTMNLEKAPLMILDKLGLLPT
EGEYNGAQEAMLPWRKSLNPKRKNEEVRPIFWQRRPYSYVARTSQWAVDEFPNGRFGDSS
SPAFGDLDLFGAPLIRQSSKKSLELWSTPTNLNEIANLVINYLNGSLKCLPWSDTPLNHE
VDSIMSNLIALNRKLIITINSQPVLNGIRSNDPIHGWGPKDGYVYQKQYLEFLLPKEKLP
VLEKKLAGNEILTYFAANSEGDLQSNHPDGSKANAVTWGIFPGREVLQPTIVEKVSFLAW
KEEFYRILEEWKLNFEENDKVASRDFLQSLIDNYVLVNIVDNDFISKEDSIFSLLMSL
>A0A504L2U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. CU2|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDHVDAVIREFADMGVKRFVALRGDPAAGVGT
IYRPHPDGYANGAELVGALKGAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHYFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
GSAAA
>A0A367ZWZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Tokpelaia sp. JSC189|TrEMBL
MPAYRLLHHGDIINVSFEFFPPRTEQMEEILWETVDRLAPLQPHFISVTYGAGGSTQERT
ARTLERILKETELSVAAHLTCVGATCAEVDQVARGFSALGIRRFVALRGDPVNGRGDVYR
PTPGGYANAVELVAGLKAIDSDFDITVSAYPEKHPESPSFAMDIDLLRRKIDNGATRAIT
QAFFDNDLYERYMEKLHAAKIDIPVLAGILPIHNFRHVSRFCSRSRTHIPNWLAYRFEGL
DKDPKTHSLISGIVAAEQVLDLVERGVKDFHFYTLNHADLAYTICHLMGIRPKK
>A0A498KDR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malus domestica|TrEMBL
MKVIEKIQESLVDEKKVVFSFEFFPPKTEDGVENLLERLDRMVAHGPAFCDITWGAGGST
ADLTLDIANKMQNLICVETMMHLTCTNMPVDKIDHALQTIKFNGLQNVLALRGDPPHGQD
KFVQIQGGFACALDLVTHIRAKYGDYFGVTVAGYPEAHPDAIAADGLASPEAYQSDLVYL
KRKVDAGADFIVTQLFYDTDVFLKFVNDCRQIGITCPIIPGIMPINNYKGFIRMTGFCKT
KIPAEVTAALEPIKDNEEAVRLYGIHLGTEMCKKILAHGIRTLHLYTLNMEKSALAILTN
LGLIEESKISRLLPWRRPANVFRVKEDVRPIFWANRPKSYISRTVGWDMYPHGRWGDSGN
PSYGALTDYQFMRPRARDKKLVEEWVVPLKSIEDIYEKFKKFCLGKLRSSPWSELDGLQP
ETRIINELLGKMNTKGFLTINSQPAVNGERSDAPSVGWGGPGGYVYQKAYLEFFCSKEKL
DALVEKCKALPSLTYMAVNKDGSWISNIGQTDVNAVTWGVFPAWEIIQPTVVDPTSFIVW
KDEAFEIWSRGWARLYSEGDSSRKLLEEVQSSYFLVSLVDNDYIHGDVFAVFADF
>E0MUF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium accolens ATCC 49726|TrEMBL
MSEEELMVPERLALSFEVIPPRHDADEAKIDRLLETLESYHPDYIAVTSSKRSGWLEGTT
AFIERISRTTSMRPLAHLACTAGSRTELIGWTNRLVDAGVRGLLALRGDLPEEGLPEHYP
QHADELISLIRQLERQQAARFAAGRLAVGVACYPSGHVESKNEDEDFDVLLKKQRLGADF
AITQLFFDAQDYLRFTKKAQLAGVHIPLIPGIMPMTSLRRVERMGELSGLAVPERVRSAL
AAATTPEEEYETGMELTAELARDIVAGGASGLHIYTHNNPDNTHDLLTRIGVDNDQR
>G0WBM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639)|TrEMBL
MSRLSIKELYECKATPSISLEFFPPKTDSGTRNLMERMGRMSAMDPLFITVTWGAGGTTS
DKTLNLAQLISKEFNVPVCMHLTCTNMERSVIDEALKKCQEIGIKNILALRGDPPIGEDW
IDSDGNPEYEFKHAIDLVRYIKETYGSEFCIGVAAYPEGHYQEDSENAIQDPVKDLVYLK
EKIDAGADFVITQMFYDVERFLAFEQLFRDNISMNIPLFPGLMPINSYLLFQRASKLSHA
SIPEKILERFPPEIQFDDDSVKSIGVEILIDIIEEIYKRTSGRVRCFHFYTLNLEKAIAQ
IVSQSPTLSHILEENESSSDDEVTPQENGIATIDADGDIVIEDIPESNNDDSDEIMIDGG
NDHGTKRRRRSSTVSTEFMMNRALVTQGRTNTTRTNQGMVGAPSKKFVISISKGSGALGR
DATWDEFPNGRFGDSRSPAYGEIDGYGSTIKVSTKRAYELWGQPKSLKDLKSIFIKYLEG
SIDALPWCDLGLSAETGLIQEELIQLNHRGYLTLASQPATNGSSSTDKIFGWGPKKGIVY
QKAFVEMFIHKQQWENVLKPKIEHYGTRKFSYYAGDSSGSFESNLDANSSNVVTWGVFPN
SQVIQTTIIEENSFKAWRDEAFTIWSEWAKIFPRNSVTNIFLREMFSEYCLISIVHHDYI
ETDELWDILLD
>A0A171KQ58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kerstersia gyiorum|TrEMBL
MTQHTCSSSLAAQPAQPLLQDYSLEMTAREIRSLADIRTLATPGTRVNITFLPNEQDADR
LRAASLVHAQGLIPVPHLAARRIRSDTELRTYLARLREQAPARHAFVIAGDPPRPAGPYE
DALALIQSGLLAEYDIRHVSISGYPDGHPAIPADVLWRALHAKHRALALQGHDCEIITQF
GFEAAPILNWLERLRQEGIEVPVRIGVAGPVGVHKLLRYAAACGVGASAGILRKYGVSLG
RLFDTAGPGMLLQDLQTGLEPARHGVVRLHFFPFGDMEKTLRWILAQAA
>A0A165GCT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Laetiporus sulphureus 93-53|TrEMBL
MKISQKIAQAEKEDRIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQKLIGIETCMHLTCTNMPKEKVDIALSEAKEHGCRNILALRGDPPMGKVE
WEAVEGGFVHGIDLVRHIRSLYGDYFDIAIPGFPQHELLPPEEFQQELKYLKEKIDAGAN
FIFTQMFYDVELFIRWVHAVRAAGITVPIIPGIAPIQTWNGFMKATSLAKTKIPQFFMDA
LEPHKNNDEKVRAIGIKLVADMCRRILKEPLGIRGLHFYTMNLEKGTRMLLEELHLVPRV
QTIKPLPWRQSLTPNRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQSKDEALQLWDRPTTVVDIGKLFAQFCIGKLPALPWSDEAPSSETSVISTQLA
KLNEMGFLTINSQPAVDGARSDDRIHGWGPSNGYVYQKAYLEFFVSPELLDALLPNIERD
VNITYYVLNKRGDLRTNTHSDGPNAVTWGVFPNKEIIQPTIVEAISFMAWKDEAYELGRQ
WSNYYEPDSPTRKLINDIMDTFYLVNVVHNDYKKPQAIFEPFFKAGAEFASAHGQAPPVL
NGH
>A0A662T5V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Geothermarchaeota archaeon|TrEMBL
MGIEFREYLMHTDTPITVEAPIFGSIDEVEKFASRLKGYKTSKYIGGVNVVNYPFGRLTP
DPALIGCLFKRYIDLEPILHIPSSLESKYTLVRTLYSLYICGIRNILLLGGDVKTEYGLK
LDEAFNYIKQFSEGYIDLEHSRLSIEKFHFHVGGAAILDRDDEVDRIIWKIRMGMKFFQT
QYIYDYNLIREVLTKLDAQLTELNLDTKVPMLLGILPYLDGDTRGILGRIGLNIFSKYDT
REYRRYINTLISRLIKLMDSIGLIKIGFHFMPIRWKDEVYEEISKIIESLI
>A0A7X4CB20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0678_bin_10|TrEMBL
MTPRTLQHTLAQGQFAVTVELNPPKGTDVSELLETAKSLSGRVHGINVPDNAAAVLRASP
VAVARLLYEQGHDPVLQLTCRDRNRLGLQSDLLGAHVLGIRNVLCLTGDSPGAGDHKDAK
PVFDLNTVQLMHAVQELNEGRDLAGNALEGRTAFFIGGAAAPGGEPTELLHKKFEAKVNA
GAEFFQTQPVFSAKVIQPFMEAVRPYSRKVLAGVLVLRSIKMAEYVNAHVPGIDVPDEIL
QELRNAGDAHVSEAGIEIAVRTIRAVRPFCNGVHLMAGRLAHRLPEIIRKAELN
>A0A836TX84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichaceae bacterium|TrEMBL
MESQKKYKPTFSFEFYPPKTPEAVAKLQTTQVELAKLNPNFFSVTFGAGGSTRDMTFETV
MDIKEKTGIEAAPHLSCIGSQADEIKAILDKYIESGITRIVALRGDLPSGSVGYGEFRYA
NELVDFIRKETGDHFEIEVACYPEFHPQAKNAQTDIENFKRKIDAGANGAITQYFYNPFA
YYRFIDSCEKLGIETPIIAGVMPIVTCTQLQRFSDACGAEIPRWILKRLQEFGDDRVSIR
EFGIDVTTELCEQLLANGAPGIHFYSMNLSAACVAIWKNLGIDQ
>A0A538M6S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPDRFEKRLERGPPVVTDGGMGVLVSSAVAGLRCPEEANIRAPESVVSLHTSFINAGAEL
IETNTFGANRHKLRSQFLENELAAINETGVKLAREAREISGRDVFVAGSIGPLGELGGLA
ADERGPVFAEQAALLEGRGVDLFMVETFFDLDELTTAIEAVQGVSSLPIVAMLTFDEDAE
TFGGVSAHDAVERLAAYELAAVGANHGAGLHAALAALEAMGDGRPLAALPNVGLASLSGG
RVIYPHATPEYFAEFAAQARALGARVIGGCCGTTPTEIAAIARAVEEERQPTAPFAAAER
ELVVAAHERPEETELARKLRAGEWITCVELDPPKGGTYESMLAVTKTLKDSGEVGFVDIN
DNPMARARANALMAAIAIERTCAIETIPHVTPRDTSVMGLQSQLLAAHAEGVRNVLSVTG
DPPHVGDYPGSRGVYEVDSIGLAQVVTRLNAGEDFNGKAIDGPTSFFLGVAVNPSADDLE
TELDRFRRKVDAGAQFAMTQALFDLGYLDRFEELLGGWPIPVLIGIFMVRSHQLAVRLHN
EVPGIVVPEDVQNRLRDAGPRAAGEGLALARELYAQAREKAAGVYVIPPFKQPEAALELL
GS
>A0A7C3YM24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSGTELKAGSNLEKVLAAGKFAVTAECGPPKSADGEVVANKARLLAGYVDAVNVTDNQTA
VVRICSLVSCHIAQQQGVEAVMQMTCRDRNRLAMQADILGAAALGIRNLLCLTGDHGSFG
NHPQAKGVFDLDSVNLIRMCRDMRDAKKFQCGEEMPVEPRLFIGCAENPFGDPFEFRALR
LQKKVEAGADFVQTQCIFNIPKFKKWMEEVRALGLHQEVKILAGITPIKSAGMAKYMKSF
VPGMDVPQEIVDRVAAKEKGEPQQAEGKRLAVEMIKELAEVEGVAGVHIMAVEWEPAVPE
IVEAAGLTPRPAVA
>A0A7S9GT69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium genosp. L|TrEMBL
MTETFSPLPNGQRAPKISFEFFPPKTEEMERNLWDTINRLAPLTPNFVSVTYGAGGSTRE
RTHSTISRILRETDLLPAAHLTCVGSSRGEIDEIVDRYHEVGVRHIVALRGDPPAGIGTP
YFTHPDGYQSSAELVAGIKRRHADIEVSVSAYPEKHPEAADFDADIDTLQAKVDAGADRA
ITQVFFDNELYYRYVDRVQARGIAIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAEKFD
GLDNDAETRKLVAATVAAGQVQKLFKRGVDTFHFYTMNRADLVFAISHLLGIRPNGAQKA
A
>A0A7K0RE38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARAYMRGSRRQRGQRSHRLPCSALVIWRSVTIPFSFEVYPPRKPEHQAALHETIQKLAT
AGPDFITVTYGANGSSRDASLDCLRFIREHTDVAPLAHVTCVGSTRDEMNALIDEFLAAD
IRMFLALRGDPPEGADPQSDYLGDVKTAAELVHLIRERGDNDLSIAVAAFPNGHPMSTSP
SSDIDILLAKQAAGAEFAITQLFFNATDYLSFLSSARAAGVTIPILPGIMPVTSLSRLRH
IVEITGERMPRDLEAALEAAPSPAHARTVGVAQAVELCRQLVAGGAPGLHLYAFNEHETV
LEVLAQLNEPA
>A0A7K0V7W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MEMRMAKVGEAVTYSFEFFPPKDQEGEDRLWSAIAALEPIKPDFISVTYGAGGSTRDRTI
RITSEITEHTKLPVVAHLTCVGSTRDELLEILARYKDAGIHNILALRGDPTGGPRAPWSP
TPGGLNHADELVSLAADFGGFTIGVAAFPDGHPASNGDFAVDIDTLIRKEAAGATFATTQ
FFFEVDKWKSLVDKLAARGSQLPIIAGILPVTNVNQLNRMSELSGTPIPGAMSDAFEKIK
DKPDDVRKLGVDLATKLCEDLLAAGVPGLHFYTMNTSTATREIFAQIKDKKRA
>A0A7K1DZ91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSTHAAVQAERATGIPFSFEVYPARSESQVESVHETVQKLAAVAPQFIAVTYGAGGSSRD
RSLDLVRYILTETNVPPMAHLTCVGSTANEANRLVRDFLDAGIRQFLAIRGDAPEDAIES
EDFLGDLRSATELVQLIHRVQSEREPYTEVDEPQWGGGAVRLSQRREPVRIGVAAFPNGH
PQSRNRAQDIDVLLAKQAQGANLAITQLFFDADDYLSFMVDARAAGVDFPVIPGIMPVTS
LGRLNRIVEITDEPMPVHLEAALGSASDAAAQYEVGIAHATELARAVLDGGAPGIHLYAF
NQHAPVLDVLTRLGAID
>A0A6I3F1J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MPQSDARSLSTMTRIADLLASGRTCSFEFFPPKTDEAARALEQTIADLAPLDPSFVSVTY
GAGGSTRERTRDVVINIEQNIGITAMAHLTCVGHTRDEIDSLLDEYKAAGVSNILALAGD
PIVDDSGDVVESEFEFASELVELIAAKGDFSIGVAAHPEGHPRSPDLYSDRRHLADKLNM
ADFA
>A0A0R2H227|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weissella viridescens|TrEMBL
MEKTIKYSLEISTPATVGEQEDLIRQLQTLPRDEIEFIAITIGAGGSIELATPVLSFIQL
LLECINVPIVPHVTGSHQTQAQVQELLRKLSGMGIQTVLAVRGDGEPNAFGHGDDLIRFI
EKTGEFEVLGAAYPEGHPEDDNLQQTIQTVERKRLAGAKALMTQVVMDNHRLYQFQQALK
TAQVSMPLIIGVMPYVQRERVIKMIQLTQVTPSPVVQGLLTQTDVNAFKSEGLALTIKQI
VDLRKHGYSHIHLFCQNDIAVVSELFQGL
>A0A7J4GRF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poseidoniales archaeon|TrEMBL
MDSGLDFLNKIHDRIPVSLEILPPNRGLGLDAIHSFFEGLKPWKPAFVSVTYHQAFKVEE
NESRIWNRKKPGTIGVCAMLKFQYGLKVIPHVICGGFSSFESEDFLVDLDYLGLDTILAL
RGDPKKGDAEFKHHRDGHRYASELVDQVMRLNMGEYMEDVKEAKSTSFVVGVAAYPEKHR
EAVSLDVDIQNLRNKVNAGASFIITQMFFDNQVYFDFVERARNAGITIPIIPGLKIITSK
RQVEILPEIFHTKMPADLCSIIQRCENDFEATEIGIKHAISQFKGLEEYGVPCIHLFSMN
NLTPITSLLKGVQRI
>A0A6I2YPU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTKINELLKESRTVSFEFFPPKSDAEAAVLGETIRDLESLHPSFVSVTYRGGAESRQRTY
DLVTMMRRDTSLNPMAHLICVAHSRGELTEILEQYRDASIDNLMALGGDPPTEPDAKVGE
LQYALELVELARSVGDFSIGVAAHPAGHPRSETLNSDRDRLARKLEAADFGVTQFFFSIE
EYRSLVNDIADRGVTKPILPGIMPVTSLSSVPRMATMGAPVPAWAIERLESAESTGGADA
VREEGIALATELCAALLEEGAPGLHFYTLNRSKATREIALALGLNQK
>A0A537WWI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSSDREGEEVPATQTGNRFLERLARGPAIVADGGMGALLSAAVPRLRTPEEANLRAPEAV
VSLHVSFINAGAELIETNTFGANRRKLGHHFLEDQLEEINSAAVKLAREAREVTGRDVFI
GGSIGPIGEPLASRVRREIFAEQAAVLEGRGADLFMVETFYDLEEVVDAIEAARSASGLP
IVALLTFDEGAETIAGVTAAEAAQRLRELDVAAIGANHGAGLLAALAALERMGKDGIPLA
ALPNVGLASLAGGRVIYPHAAPEYFAEFAAHARDLGARVIGGCCGTTPAEIAAIHSAVEE
DRKPRAPLQFDERELVVSLGEERRETGLSRALRENEWIISVQLDPPLGGSSVGLVEVARA
LQESGRVGFVDINDNATARAGMSSLMVSATIERECGIETIPHLTTRDWSVLGLESMLLGS
HAEGVRNVLAITGDPPEVGDYPGARGVYEIDAVGLTQLITNLNRGEDFNGRPIDAPTSFF
HGVAVNPNADDLDLELERFQQKLEAGARFAMTQIVFELECLDRFAERLGGSWPIPVLVGV
FPVTSYRLALRLHNEVPGIVVPDDLQNALQDAGSEAAEIGFEHARMLIAESRRFAGVYVV
APFRKPLRVLELL
>A0A6J4HLQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Actinomycetospora sp|TrEMBL
MSLDIPLDITAELDVPHRPDLAPIARQLDALAPVAARFLVPDNATARAAVAGLVVAAEVR
RRDAETVAVLNARDRNTLGLRRDLLGLLALGVREVLLLRGDRPDDDEEDGPLTVGTMLRE
ARALAEEHETTLRVGVVAAPGRDLPRWKRDADVVWLAPTFSLPAVTDWRERHPDLAAPVR
AGVLVPTGPEMARGVAEGMDLDLPAGLVEALGEDDTAGVDAACEHALALRDAGVDGIHLV
AVSRYREVAQRLAGLV
>A0A089LS61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus stellifer|TrEMBL
MKPDLRTAWGAKVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEEVHRSYIEAGAQL
LESNTYSANYDKLSKFGLESKVEEINRAGIRIARQAAGANGYVVGAVGSIRAGKRASLSA
SELKRYFSQQIGALLEEQADGIMLETFYDLEEMHLALRTVRKLSTDIPVICQFAVDETAM
TMDGLTLPEAFRILEEDGADVIGFNCRTGPFGIKRALRTLQDSLSLPVSVFPNAGLADYV
DGHYKYGASPEYFGQMAESFADMGCRIIGGCCGTTPQHIAEISEALKEYSPKPLPERKER
STVNVRIQESLAEHDGDGGQEPTLVDLVKERHTVIVELDPPRDLDITKFMAGADALRRAG
ADALTLADNSLAVTRMSNMALGSLVQQKTGLRPLVHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKHKAKFVIGTAFN
PNVKHLGKAVERLEKKLAFGADYIMTQPVYDKALIHTIADATAHLNVPIFLGIMPLASGR
NAEYLHNEVPGIQLSDEVRLRMSGLEGEAGRAEGVAIAKELLDAAMERFNGIYLMTPFMF
YGMSVQLLEHVWAKTGRQLSPLFR
>A0A7C2HT99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDRRPPRPGGRVARGGAGGGGLSRASLLGDAAAERVLTTSCGPLRRADASELRARLGALR
GAFRFVKFGDSPRGVASVSPWAAACLALQEGFEPVVHVACRGRDRVSLRAELLGGRVLDV
RHLLCLRGDDPPRGRAFREVDVLELLAMARGVDEGWTLLAAADPGLEPTPAVLGRLRAKV
AAGAALLETQPVFDVGAFAGWLAAVRAAGIEAPVLVDVFVLSGPEEAERVARIPGVGVPA
AVRRRLREPGGGVRVAAELVGELRGLPGVIGCHLSTFRGDVELVLAVAEGLR
>A0A7K0W649|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSKLRDLLTQTKDVVYTAEFPVIDGGGMDQVKKNVERLAPWFAAVNATDNTAAHAHASNV
SVAIAMKQHGLEPIMQIVCRDKNRLAIQADMAGANLHGIENIALLTGDDVTAGDEPETRR
VFDLDGPQAINVASILNAGTYLSGRKLNPAPNFFICAVENPFAPPHDYRIERALKKHRAG
AQMLQLQIGYHPDRLEKFCAGVAATVPELALIPSVVLVKSSKPLNFMNDKVPGISVPQDV
IDRVAQSSDQAEAAYQLALEQCQHALALPGVRGLHITDFRHDETLERLMHDLGRTPNQYT
>A0A353FWX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDGGDLDTVAEAVDRFQPYVDAVNITDNPAAHAHASNVSMAIAVKQLGLEPIMQVVCRDK
NRLAIQADVVGAQMHGVTSFCALTGDDVTAGDEPEARRVFDIDGPQLVSIMRTLSDGTYL
SGRSLKHHRELLIGAVENPFAPPAHVRVRRARMKVDSGARFLQLQIGYEPEKLEAFVQGC
ADNGVCRDAAVLPTVILTKSAGALRFMESSVPGIHVPADVIDRIASASDPLEESYQLARE
QAAHALSLPGIAGIHITDFRHDDSVHRLVRDLRLGPAFSSEGATTHASTTHTQTA
>A0A359LM24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MNLREKLAANKFVVTVELDPPQTLNIDKILREVNGTDFRKIVDAVNVTDCPLAKLRMSPI
ALSHIIQEKIGLETIFHITCRDRNLLGLQAELLGAAALGVRNILALTGDPPDMGDYVKIT
GVYDVDSIGLIKMVNSLNNGYKYLGGELKDRTDFFVGAAVNPTASNLKKEIEKFEEKVSS
GINFIQTQPIYDVELLKKFLKLTSHINIPKIIGIMPLKSYKMVEYINNNLPGIFIPYKLQ
ERMKGKDVKEGIKIAREIINKICKLKEVAGIHIFPLRDMELVCSLLNQSLVNSK
>A0A538AKM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTLDETLVPEEQPLARVVRAAAFELIPLASVYDRAMALPHGSTVTVTVSPTRGLEPTLEL
AESLAERGFAVVPHLAARTVRDRVHLAELVARLDAAGLKNVFVIGGDGEDPGLFPDALSF
LRAVEELGHRFKSVGIAGYPQGHPSIAMDALWLSLLAKQAHADYVTTQLCFDADATAQWI
DDARRLGLTLPIHVGIPGPCEVARIARIAARVGVADAARYLRKNRGLLGALIRRRAFRPD
RLLGELVTTIADPEANVEGLHVYTFNQVEDAVAWRARALASPAIS
>A0A2E6XSN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTTTQDSTPVPPKEPKGRRSIRSKSDRDVHRHLLEGMTFELIPLGNLEDQIRFIPTGSTV
SMTCSPARTVEDTLNLCEQLGNYGFATIPHIAARMVXGEAHVDQLVARITGLGIRKVFVI
GGDTEPHGPFTDAAGFLRSFLGRKPDIDVVGIGSYPDGHDTIPDXALVDALLEKQELIAE
AGLEGYMSTQMCFDHQKIGNWLVERRAAGVTLPCYLGVPGAVDRTRLLTISIRLGIGHSA
RYLKKNRSSVIRLLSPGGYNPNKLIGPLSKRATDLDITGIHCFTFNAVDTTEDWRQKALA
GLKH
>A0A2S6SI75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha5_Bin7|TrEMBL
MATNYKELLIKELIKDFSIETTPNVYNKYGTFIEMLPKKNDVYVTYLPDENPDNVVNTCK
KLNLEGFDVIPHLPARTIKDIADLEKYIGSLSENAGCKKILIIGGGGNQKGEISSSIEVL
KTDLLSKFNFTQVGVAGHPEGSPDISNTELDKAIIEKNNFANNVDFKIYIATQFFFEASI
FEKWEYHLNSLNNKLEIHAGIPGPATLKTLISYATSCGIRNSIRFLSKQALNITKLASSK
TPDKLITDLALYKQENPASRLAKLHFYAFGGIKKTSEWLSLILDSSLEINSNNEFKPDKK
>A0A6J4J653|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Actinomycetospora sp|TrEMBL
AGARRGLSRRRVRRPPGEFSRRLAARAPALRGGAGGGRARGRRRPARRGDGGGDRLPEPW
SGGHDRGRRGPRRAGVRGRAPPRGPQPARPRRAGRPPRPARRGRRRRGVRRGRRRPGAGR
GVRRRPRPAAGDRGARAPPAAGGRAVVPRRSPPHRGRRAVGGPGGQAPARRPHRHAAVLR
RRPRLRLRRAGTGAGDRPAGDRRRPRRRRHRPAAADQRPHRRRRRGAVRPLPPHDGRGAA
TAQSHRSSSAPLRVGEPPARRAGGGARCRRGRPRGTAPLHVQPDRADRAVAVAGPPRGRL
>A0A6D1W6I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. JMN1|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAAQLATYHPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGANSAITQYFFNADSYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>W4SNR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. pruni MAFF 301420|TrEMBL
MLTRSAGPAAMTHLSFEFYPPKTDDQRAQLDRTAARLRGYAPEYVSCTFGAGGSTLSYTS
ETVRHLKQKHGFDAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDL
RYASDLIAFIRAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYN
ADAYFHFRDAVQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWISKKMQSYGDDAD
AVRAFGAEVVATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A5C6ZKL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Subsaximicrobium wynnwilliamsii|TrEMBL
MKVTEHIKKANSTTQFSFEILPPLKGHDIQSIFNNIDPLMEFHPPFIDVTYHREEYIYKE
LENGLLKKLVVKKRPGTVGICAALQNKYNIDAIPHILCGGFTREDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPEKEGHCYATDLVAQIRDMNKGNYLHAELENASKTNFCIGVAGY
PEKHMEAPNMYSDLHFLKKKIKNGAEYIVTQMFFDNKKFFDFVDKCQKEGITIPIIPGLK
PISTKKQLNMLPHRFHVDLPEALISEVLKCKDNAQVRQVGVEWCIEQSKELQKAGIPVLH
YYSMGKSDNIKAVASAVF
>A0A427FJH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. o96-267|TrEMBL
MSQQRRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTVNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNRYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNLEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRVFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLSIWNNLKLPR
>F3LI46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|gamma proteobacterium IMCC1989|TrEMBL
MNDSEFRLSFEFFPPKTDEGKEKLIHVRNTFGEFSPEFYSMTYGAGGSTRTNTKDLVKKF
QQEGFASAPHLSFGGDGEEEIKALIAEYKAAGINRIVALRGDIPSGMGSASQMVYANQLV
AFIREHFGDHFHLEVAAYPEIHPESTNYNTDVQYLKGKFDAGANSAITQYFFNLDAYFFF
VDQCQKAGIHQPIYPGIMPIINIKNLIRFSKACGAEIPRWLRKAVEAYGDDQESMKAFAS
DMVTELCEGLIESGAPGLHFYTMNQVEPVKTIIDNLKLADKKAG
>A0A2N2S6Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-2|TrEMBL
MSDPVISFEFFPPKTAEGVAKLRETRKQLAQLQPKFFSVTFGAGGSTRDRTMDTVLEIQN
EGHEAAPHISCISSSKQEIAELLQAYKAKNIRHLVALRGDLPSGEASAGDFRYANELVAF
IREQTGDWFEIEVAAYPEFHPEASSASADLKNFKAKVDAGADAAITQYFYNTDAYFRFVD
QCQALGIDIPIVPGVMPIYNYTQLARFSSVCGADIPRWLSLRLQDFGDDLPSLRSFGMDV
VTELSERLIAGGAPGLHFYTLNQAGIISTIMQRLSLPAN
>S7RQC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gloeophyllum trabeum (strain ATCC 11539 / FP-39264 / Madison 617)|TrEMBL
MKISKKIEQAQKENKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
DLTSELVKTCQKIIGIETCMHLTCTNMPKEKVDIALREAKQHGCRNILALRGDPPVGQDE
WEAVEGGFRHGIDLVRHIRKEYGDYFGIAVAGFPQHVRLPPDEFEFELKCLKNKIDEGVD
FIMTQMFYDVDIFIDWVKAVRAYGITIPIVPGVNPIQTWNGFMKSTALARTTIPQWLLDL
LEPHKNNDEKVREIGVKVVADMCRKILQADIGIRGFHFYTMNLEKATRMLLEELQLVPRV
ETIKPLPWRQSLTPTRRNETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGISLNKTKEEAAKLWDHPTKFEDVAALFRDFCRGKLAALPWSDSPPSPETTVIADKLA
KLNELGFLTINSQPAVNGARSDDRRFGWGPSNGYVYQKAYLEFFVSPELLAMLLPYIERD
PNITYHVINKTGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGHQ
WARLYEPDSPTRKLISEIMDTHYLMNVVHNDFKSEDAIFEPFFKAGEQYAASKANGTVNG
R
>A0A259IUY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. 39-46-10|TrEMBL
MELSVEFFPPKTPEGEGKLHLVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AVVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
AETGDWFHIDVAAYPECHPQAKSPATDVDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YDLGVTQPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDTASIRAFGEEVVT
DLCDQLLVAGAPGLHFYSLNQADAVLAIADNLSLNK
>A0A3A6WHN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella atypica|TrEMBL
MTLREKHQNGQFTITVELDPPKSSSAQKVFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNEGIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDHGDHPFAQSV
FEVDCMGLLNIAKTLNSGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNGA
HFVQTQPIYDLEQAKRYIDKMSEFNVPIMLGLIPLKSFKMATYLHEKVPGINLTQDILDR
VEKGGKEAGTEIAIETLEQINKIAAGVHIMPLNDIDTTLHIIDHV
>A0A538KLV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAGYDGERNLRKTLEDLRAFDPDFVSVTYGAGGSTRDKTVELTKWIKQELGIEAMAHLSC
VGTTREELLAILDGIRAAGIDNVLALRGDPPRGETEWTPHPGGLHYSTELAALISGSYPF
SVGAACFPEVHPEAPDLAHDLRFLKDKLASGATFLITQLFFDNELYFHFVEEARAVGVEV
PIIPGIMPITDLKQIKTITGMCGATIPEPLLEALEWRTGDPDAVRQ
>A0A3C1DG89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSVRVGDLLKTGSQSFSFEFFPPKTDAGEEALWSALGELEPLAPTFVSVTYGAGGTTRDR
TVAITGRIARQTSMVPVGHLTCVGATVDELRAVVTEYGDAGVHNVLALRGDPPGGPGGEW
VAHEGGLNYASELVSLVRDGGDFCVGVAAFPDPHPASGSHEVDVQVLKAKQEAGAEFAIS
QFFFKSESYFDLLARARSIGVEIPIIPGIMPVTNLAQITRFAALSGADFPAEIAAEFAAV
DEADVRALGIEKASQLCRELLDGGAPGLHFYTLNRSTATREIYAHLGLGASA
>A0A3R9RG96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSKEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KKAKSFLIKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQVGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEITRFSCQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A0Q9SWG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. Soil787|TrEMBL
MKLDLRTALQRDIIIGDGAMGTYLYQMGFPVGISYEELNLLRPETVADVHRRYFEAGARL
IETNTFSANREKLSKYGLEGDVEAINRAGVELARKAVGDEAYVVGAIGSIRAGKRKNVRT
SDVEESLREQIGILLDSPVDGLLLETFYDLEELQLALRIIRSMSELPVICQFANEGTGST
QDGVPLQEAFGRLRDDGADVIGFNCRVGPNGILRSMEKLTPIAGIPFSAFPNAGLPDYVD
GHYTYAATPQYFAESALRFADLGARIIGGCCGTTPEHIAAVAQALQGYVPAAPGTVSSAR
AVRVSEPAPAKPAPPAGKPSLLEIVKQRKTVIVELDPPRDLDIEKFMQGSKALQDAHVDA
ITMADNSLAVTRMSNLALGYLVQERLSTRPLIHIACRDRNMIGTQSHLMGLHALGIDHVL
AVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFVVGAAFNPNV
KHLDKAVQRLERKIEAGADYIMTQPVYDAKLIEQIYEATKHLNIPIFIGIAPLASGGNAE
YLHNEVPGIRLSDEVRERMNGLKGEAGRAMGVEIAKELLDAAMPFFNGIYLMTPFLAYEM
CVDLTKYVWEKSNRHDFHLYPLSK
>A0A7Y3P434|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eremiobacteraeota bacterium|TrEMBL
MDIAEQLASRRPFFSFEFFPPKDDAGREALFATIASLEALGPAFVSITYGAGGSTRARTV
ELAKQIAERTGITVLAHVTAYGQSRPELRALFDELSRAGIRNVLALRGDPPRSGEVNAGE
FPYASDLITYLARSYDFCIGAACYPEVHLEAASPEADLAYLAAKVAAGARFLITQLFFDN
DKYFAFVERARAAGINVPILPGIMPITNYDQIARFTKMCGATFPPKLIAELEKQREHPKA
IEDLGVAYAAVQAMELLRGGAPGVHFYTLNKSPAARAIGSALLAASAWRPVFK
>A0A7D4QGC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquiluna borgnonia|TrEMBL
MSTPISFEVYPPRNPESAPALYEAIDVLGELGPKFISVTFGAGGTDTSGSIEVLKYINEN
TSAVALAHLTCAGTSKTELDSVIGEFLQAGITDFLALRGDLPIGLSELPTDSLKTANELV
SLIRSSAKDRAKQIAVAAFPNGHPESGANRADLVALRAKQDAGADFAITQLFFYASDYFN
FVTLAREAGVTIPIIPGIMPIISHKRLARVLELTGEREPVELAASLAAAQDASERTEIGI
SWAANLVAELSQGGAPGIHLYAFNEHKNVSEVLRRAQLV
>A0A8H7TQW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bionectria ochroleuca|TrEMBL
MHIKQMLTEAEGTGQPSFSFEYFPPKTAQGVQNLYDRMGRMYNFGPKFIDITWGAGGRIA
ELTCEMVHQAQAVHGLETCMHLTCTDMGMEKVNDALKRAYKAGCTNILALRGDPLATRRS
GRPPRTGSSMLATSSSISGKNSVIISTLAWPVTPRGATTTKMRTSSSTTSRRRLTKVLLS
LLHRCSTMWTTLSAG
>A0A6N6T1T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiaceae bacterium|TrEMBL
MAVLTAAGDQASAADVAAVAAELVACGSLEMGAETPDDARRIAELLPTGTPVYVNHLPRH
ALDRGHGALLALHGAGLEPVPHIAARRVASRSEVQTFLDRAVRTAGVRKILLVGGDSPEP
AGPYADAAALLRDVSLAGCGVQQIGLAGYPEGHPRIPTTLLNTAMVEKLGLAERQGLGAY
VVTQFSFAPNRIVEYCADLARRAPGVPIYVGLAGPATPVALLRFARRCGVGASLRALQAQ
GMGAVRLVTHADPSEQLAALARHCRSGSASNVVGVHLYSFGGVAATAAWMNERITTRRG
>R5DRA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:86|TrEMBL
MSANGKEKIIEYLKSNILVTDGAMGTYFASLYDTKEPPEYCNIKDSKKIYDIHRQYIENG
AKIIRTNTYACNTFTLNYEIEDVKESIKCACKIAREAAKGHEHIFIAGDIGPITYNHNDM
QKQVSDEYVVIAKTMIESGVDAIVFETFPDMDDIKEALKYIAEKGNIFVIVQFAVNQFGY
SNSGLSAKKLISDALDCEYTDAAGLNCGVGPGHMYGIFEKLGINTAKYLTALPNAGYPQS
VSNRMVFAADNSEYFSIKASDMAERGINIVGGCCGTTPEYIAKLENAVKNMHPVKHFSEE
HEKKIMFKPIDKSFYKDKSGKKLIAVELAPPVDSDDEKLMDAAHILKKSGVDVLTFPDSP
SGRTRADSILMAEKVHKETGMAVMPHICCRDKNAIAMRSQLLGAHLNDINNFLVITGDPI
PSMVRQSVKAVFNFDSVGLMNIIKDMNESQFENSPIVYGGAINQTRRNLDVEISRVRKKM
DAGATFFLTQPVFEDKGIARLRQIKQETGARILCGIMPFVSLKNATFMKNEMTGIEVSDE
IIARYKECVTKEDGESVGVEIAKEVIEKTSDFVNGYYFSFPFNRVYLLERII
>A0A849TI19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiaceae bacterium|TrEMBL
MNSNTPRKSRLVGSGEIDVSFEFFPPKTDKMEEALWSAIRRLEPLGPEFVSVTYGAGGST
RERTHTTVSRIVKETTLKPAAHLTCVGATRDEVDAV
>A0A3A0EUR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MLALRRWSVRRAHALWRLWRILAARAPRCAPLVRRIGRGRSESLLRPLEHGAKRLFFDCR
MCGQCVLSSTGMACPMNCPKRMRNGPCGGVRADGGCEVLPAMRCVWLEALDGRKAIASGG
GDAAATRILPPLDHSRRGASTWLQAICDASSPRTPQERASSTERGIPQPAATVDFEEACR
SKRIVVTVEVAPPDSADPAALVRRAAHFDGLVDAINITDGAGGNCHMSSAAAAAILAASG
RTPVCQVACRDRNRIAIQGDLLGAAALGVRNVLCLTGDDVSRGDHPQARPVFDLDAVSLL
GIARRMSERGEFASGRRIEAMPLLFLGATANPFVPPYRDRVANLEKKIDAGARFVQTQFC
FDVAALAEFMREVRARELQRRCTILVGVGTLGSARALRWMAANVPGVHIPEPLLLRIEGA
ADQKAEARRICLETIDAVLGIDGVRGVHLMGHRNEEVLAGIIVASGLRERPPARAASLKP
A
>A0A7X5LVD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPDSIEKVLHFSGK
ARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQAKSFLTKHDYSQ
QILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVKTGKEFTPEIARFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWKNSVVAKVLLKTEVLSKHSLV
GCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVKQT
EILKEKLIPTVPIETRGTSSWKNWYLAIET
>A0A1S9J0Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella boydii|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRTLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4V1UJP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium|TrEMBL
MLTPVSFEFYPPKTDEQRTQLDRTAQKLKAHAPEYVSCTFGAGGSTLSYTSETVRHLKQS
HGFDAVPHLSCVGGSREEIRELLRLYRALACKRLVALRGDLPSGMGHAGDLRYASELIEF
IRAEHGDAFHIEVGAYPETHPQSDDALVDLKHFKAKVDAGADGAITQYFYNADAYFHFVD
AVRKLGVRIPIIPGIMPISNYSQLKRFSESCGAEIPRWIGKRMQALGDDADGIREFGADV
VAGLCQRLLAGGAPGLHFYTLNLAKPTQAVLSRIS
>A0A418VYB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum cavernae|TrEMBL
MTAPLSPLPSVSFEFFPPKTEKMEQSLWQAIHRLAPLAPSFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPDAAGGVGGAYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPESHPDAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDAYYRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPAALSDTFEGLDA
DPETRQLVAATVAAEQCQALQAQGVTDFHFYTLNRADLTMAICRMLGVKAHSPAAPVAG
>A0A0S9SHI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. Leaf113|TrEMBL
MPSASHHRASRDGYRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVKETGLQPAAHLTCVDATREEIDAVVQSYWDAGVRHIVALRGDPQDGVG
TAYRPHPGGYAQTADLVAGIKRIGDFKVSVSAYPEKHPEASSLDADIDALKAKVDAGADQ
AITQFFFENDIYLRYVDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLDNDVETRRLVAAAVAAEQVLDLVDHGVNDFHFYSMNRSDLVYAICHVLGLRSQAPKT
VAKAA
>A0A0R3ESD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides sp. H072|TrEMBL
MTTNPLDHDASVAELQDPGSIADRLAGVQPGDVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDLE
RDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEEQLLRAAGDGPEEDRDEVRKVGVEVATSMAARLVAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A7Y0KF83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora sp. TBRC 11914|TrEMBL
MDGVTAVAEALAARPLLGDGAMGTLAQATGARLEGAGSELALVAPELVTALHRRYLDAGA
EVLQTHTYGASRLRLARHGLGPRVRDINLAAARLAREVVDDAAPGRAVFVAGSVSPATSP
RAPGPVDPAAVRAALREQVAALDEGGVDLLVLETFAHAEELAEAVEVAREASDLPVVAQA
TFVDEDGAPVTTHGETPEQVAHVVGALRPLAVGSNCTLGPQGLLAVVRRMAASVPEGVLV
SGLPNAGLPHVVSDRSVRFASDTAHFGRYVAHYVAAGARLVGGCCGTTPAHVAAAAAALA
GAPEPLTREPAAAPARPVVTVGLGTAALPDPAAPDGEPGTVPGPGRGALGRWLDADHRTP
LLVAEAGGNGTDDLGAGLARGRAALEAGARVLWSGRERSRRPRTTAAAVAAGLHEAAAAD
VMLTVTSWNTSRMALQADLLGLDALGIHALVCETGNPPVHADRPVRDGVWEVDALGLVEL
AASLARGVDPDGSTLPLACPFRVGVRVTPGADDLDRELARTRAKIRAGAEYLVTRPVYEL
DRLRRIRAGLDDRRTPVLMTVAPLSGFAEAEQLRHEVPDVVLPEPVLARARDAGEDPAVG
LDLAADLVAEAVGEGLVDGVVVRRAGSPERLAEAVARLGAALGT
>A0A0M2PQG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. SA1-12|TrEMBL
MSFLEDLQKKILIGDGAMGTMLYSHGVDRCFEELNLSKPEDVLRVHQAYIQAGANVIQTN
TYGANDIKLSRYGLEDDIRQINKQAVEIAKRAASPSTYVFGTIGGVRTFKKSAHTLEEIK
RNFREQLFILLNEDVDGILLETYYDLEEMKIVLQIAKKETTKPIIANVSLHEAGVLQDGT
TVTKAFSLLEELGANVIGLNCHLGPYHMIQSLEEVPLLKHAYLSVFPNSSLPALNEGRLV
YESDEGYFRESAQKFREQGVRLIGGCCGTTPKHIQAMAEAVSHLAPVTEKKVRTPKQQQE
TIVTKNTEALPPLEDIVMEKRSVIVELDPPKKLGMNVFLDGAQALHEAGIDALTLADNSL
ASPRISNLAAGILAKEKTGGRMLIHITCRDRNLIGLQSHLMGLHSLGLTDVLAITGDPSK
IGDFPGATSVYDLSSFDLISLIKQFNEGVSYSGKPLGAKTNFSVAAAFNPNVRHLDKAVV
RLEKKIAHGADYFISQPLYSNQQIIDVYEATRGLKAPIYIGIMPLTSSRNAEFIHNEIPG
IKLSDSIREKMAAAGSDKEKARQEGIAIAKDLIDTAFDLFNGIYLITPFLQYDITVELTN
YIHEKEKQLAERKITHV
>A0A8C0ED47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bubo bubo|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPVIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNSPTQHTKAP
>A0A7H9DN30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus sp. 17KM0847|TrEMBL
MSRLLDTLKHKVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVERIHKSYIEAGADIIQT
NTYGANFEKLKQFGLEHKVKTIHQAAVDIAKRAATEDTFILGTVGGFRGVKKGELSLSAI
LYHTEIQVDTLISSGVDGLLFETYYDLEELLKVIKATRTRYDIPIIAQLTASNTNYLIDG
TKINDALQQVIAAGADIVGLNCHHGPLHMKNTFSHIALPKQAYLSCYPNASLLDLDNDTF
KYSNNAEYFGNTAQQLIQEGVRLIGGCCGTTPEHIRHIKKSVNHLKPITEKKVIPIHKKS
ESTARTNHRLSLAERARRQPTIIVELDTPKHLDTTRFFDNIKALDDARIDAVTLADNSLA
TVRVSNIAAASLIKQQFNIEPLVHITCRDRNLIGLQSHLLGLSLLGIHEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGINTDGDALKTKTHFNIAGGFDPHVRNIKAAVRK
METKIESGMHYFITQPVFTQEKIIEIYEATKHLDVPIFIGIMPITSYKNALFLHNEVPGI
KMSDDVLAQFEAVKNDRVATYNLSLSLCKSLIDKVHQYFNGLYLITPFERVDYSLELAKY
SKTITDNNQEVLL
>A0A7G5XC66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacibacter sp. S13-6-6|TrEMBL
MKSLKEKIEARENGLLLYSFAPPKITTEKEKLQIIAEKQINRINDLAIDGLILYDIQDES
HRTNEQRTFPFIQTVPPEEYFRNYLSSIKTPSIIYKSIANQTKETFNEWLSKNNDLENFV
FVGASSSAQIAETNFALTDAYDLRKDQHQHLLLGGITIPERHSKKGDEHKRIFSKTEKGC
SFFVSQCVYNVYESKNLLSDYHYDSIDNSYELQPIFFTLSPCGSIKTLEFMKWLGIEVPK
WLYNDLKHAKDILNTSVKTSIMIADEILEFAAQKQIPVGFNVESISNKKDEIDAATEILN
TIADRLKHTRKKTSAEKITAAEV
>A0A625JRR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter coli|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKIISILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYDNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVNGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A8J8W2D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium sp. RFL-2021a|TrEMBL
MHIRDMLASKEAAGEPGISFEFFPPKTAQGVQNLYDRMDRMHSLGPSFIDITWGAGGHLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPLEKVDQALKSAYRAGCTNILALRGDPPRDKET
WEATENGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNSDIDQLIDHLKEKVDAGSSF
VITQMFYDADHFIEWVKNCRAKGINVPIIPGIMPIQQYASFIRRSNWTKCRVPPEWMEAL
EPVKNDDAAVREVGKRLIAEMCRKLMASGINHLHFYTMNLAQATKLVLEELGLAPSEEAP
IQRPLPWRPSLAPGRRTEDVRPVFWRNRNSSYIARTQTWDEYPNGRWTDSRSPAFGEVDA
YGVRLKGTNDQNIKLWGEPKSVKDLSDIFIRFLAGKLDRLPWSDSPISAEANDIKDQLID
LNRRGFLTINSQPAVNGVKSSHPIYGWGPKNGFVYQKAYLELLVPPTLINELIARIEQND
DLTYHAIRKNGELRTNTNDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYRLGEDWS
KCHDSSSPSRKLIQEVVDDWYLVNIVDNDFHRSNAVFELFKDLEVPDLNTELSGKPVTNG
SADHNGSANGH
>D9SNK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B)|TrEMBL
MKIKDILDNRQSFSVELFPPKKTDSFDNIINTLDNLNGLDIDFVSVTYGAGGSSRDNTVK
LSKKIKSEYNLEVITHLTCINSKKDEIASLLDEMKENNLENILALRGDIPSEVIYDDYKY
ASDLIPEIKSLGDFCVGAACYPEKHPEAPSNVYDIKKLKQKTALGCDFLISQLFLDNTMF
FNFQERLELADVNTKVLAGIMPVINKAQFERIIQLSGCNVPPKFKKILEKYEHNPSALKD
AGIAYAIDQIIDLMCHDVDGIHLYIMNKPENAKRILDNITGLRNA
>A0A373CKG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM34-11AC|TrEMBL
MNLREYLKTTNLITDGAFGTYFAAKYQTQDIPELANITAPEKVKKIHEEYLNAGAKFIRT
NTFASNTETLQEDFAEVEKNIQAAVEIARDAVNGRDAWIAGDIGPIPVNGAEDAAAAADE
YYQIAKTFAECGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIGEMSLWDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLNVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTKEDAARLRRIKEETGAKILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>A0A1Y4U8I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. An116|TrEMBL
MNVVDIIREAIATKRTRFAFELLPPLKGDGSQKIFAAIEPLMPYRPAYINITFHREAIKE
TVREDGSIEWHVVRRRPGTVGISAAIQQRYGVEVVPHLICGGLSKYDIEDTLIDMDFLGL
HNVLALRGDKSQNERRFMPHPQGHAHAIDLVRQIDDMNHGRFIDGEVEECHHSKFSIGVA
GYPEVHFEARDITSDIAHLKAKIDAGAEYVITQLFFDNRKYFDFVRRCREAGITVPIIPG
LKPLSTPRHLEVLPETFHVSIPEELAREVKAHPESAREIGTEWAIAQSRELMAAGVPVLH
YYTMSRTTNIQKIVSALF
>A0A242P1T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella sp. A7|TrEMBL
MKTNLLFNQKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHAVKHTYGIESVAHLPGINFDKTEMLKILHDLKCAGIDNVLALRGDISPNVAPKDDF
RFASELVTFIKENGDFNVIGACYPEGHLEAATLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYAFLDKAHDMDINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKSA
>M1WR66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio piezophilus (strain DSM 21447 / JCM 15486 / C1TLV30)|TrEMBL
MHIPDMIQELERPFISVELLPPRQDREQNAFWNAVETMKTMNPLFTAVTCGAGGSGSMGT
LKTSCELVQGHGLTVMPHVTCVHSQLSGLKRHLENIQIGGIRNVLAVRGDYPAGVESAPE
GLRYASDLVERIGELAPDVAVGVAAYPDGHPESKSILEDIRFLKHKLDAGAAFGVTQLFF
DNRRYFDMIDRLAAMGCNKPVIPSILPVRSMGQIKRVMELCDAPVPGKFLHAIEAAHAKG
GDDAVKEYGIGMAADQISSLLENGAPGVHLYPFNRAEMCVEVMQRAGLAA
>A0A6G2ZMH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID3915|TrEMBL
MTGAADEGLRVALTRSTPTFSFEFFPPRTAAGGRALWNAIRRIEPLAPDFVSITYGAGGS
SRDRTVEVVRRVVTETTLRPVAHLTAVGHSAAELRRVVGRYADAGVRDVLAVRGDPPGDP
RGAWSAHPDGFTHAYELVELIRSLGDFTIGVAAFPERHPRSTDWESDIRHFVAKCRAGAD
YAITQMFFDVEDYLRLRDRVTAAGCDIPIIPEIMPATDVRRISRFVELSGCAFPEDLAHA
LEAARDDPAAGHRVGVEHATAMAERLLAEGAPGLHFITLNSSTAATDIHRTVAPARPVPP
AGTGAVRGALPAGGAPVGLPGQA
>B6YQP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azobacteroides pseudotrichonymphae genomovar. CFP2|TrEMBL
MSVIDLLNNDFETKFSFEILPPLKGNNFSKVCDIIDKLREFIPKYINITTHHSENIFKEN
NNGTLTKINVRKRPGTVAIAAAIQNKYHIPAVPHIICKGFTREEIEYALIDLQYLGVTDL
LLLRGDVNKLEQDKIDSNKSHEHTTELIKQVNNFNRGIDLLGNRFEEPETPFSFGVACYP
EKHEEAPNMESDIAFLKQKIALGAEYIVTQMFFDNQKYFEFISRCHRENIAIPIIPGIKP
IISLDQLTVLPKIFRIDLPEILTNELRKCKTNESIQQLGVEWGILQCKELINSGVPSLHF
YTFMATDSVQKIVKEIY
>A0A0Q8EQX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Root63|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVRA
TQQIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDP
AAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A0B2W4Y1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Toxocara canis|TrEMBL
MTTTFITGESDDNVKKGDSLPLFPYSGGYKNGNGNGNRNVTTSESEIVMKQCSELSGKLS
QGNTYIPLHERIRKRIEDHSPFFSLEFFPPKTMNGVANFFMRLDRLREGNPMFIDITWHL
SSDPGNIKKETSSMSIAASCLNYCRVHTMLHVTCAQYTKEQTLRHLEMSKALGLRNILAL
RGDLPKQDENPVVYNFRALDMIRWIKEEYGDYFTIACSGYPTCHPEAPSYAADLRYLKSK
VDAGAQLIITQLFFDADVFEKFVHDCREIGITVPIIPGIMPIQSYESIRRIAAVSQLTIP
ESILNTLEPIKHDDDAVRSFGIRHAVEMCRHILSSGSALSVHLYTMNRESSCREILQELG
LWTRTPMRSMPWKSFDGNHPLRAKEDVRPIFWSTRPKAYVFRTRDWDEFPNGRWGNSSSP
AFNDLADYYLFYLKGQPTKDEQLRMYGQELESVEAVKKVFVGFITQQPNEQGVKVTRLPW
NEQDLDAETNIIRDQLLWCNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKGYLEF
FTCQKNAEILQRILPSYPRLSCHIINHDASIDWTNTDATTPIAVTWGVFPGCEIAQPTVV
DPLSFHVWKDEAYEAWMNWASIYPEESKSRKLLKEIHDEFCLITLVDNDFPKPLIIFDVL
AEVLQIAAATDKTS
>A0A2I1G8H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus irregularis|TrEMBL
MKVINKILKAHEEGRPSWSFEYFPPKTQQGVQNLYDRMERMYRLGPEFIDVTWNAGGTTS
QLTSEIVATAQSVYGLETIMHLTCTNMPKEKIDKALKDAKECGCQNILALRGDPPRGQEH
WEACENGFSHAIDLVRYIRQQYGDYFGIAVAGYCEGHVDNPDKDDDLYRLKEKVDAGADF
IITQVFYDVDIFLNWVKKCRAIGISCPIIPGILPIQNYSGFNRIITLSKTIVPQFVLEEL
EPIKDDDAAVKEYGIRLAVDMIRKMFADGIKCYHFYTMNLERSTRLILEALEFVPPIENV
KPLPWCPSLSAKRKKENVRPIFWRNRTKSYIARTEAWDEFPNGRWGDSRSPAFGELDGYG
VSLKHSKKGALELWGYPQKHSDIFDVFVQYCRGEVNSLPWSDQPLAEESNIIREQLAHIN
SLGYLTINSQPAVNGVRSDHKIFGWGPKNGYVYQKAYLEVFISPTQLDALIARIERDTNI
TYYAVNKQGDLKTNTQSDGPNAVTWGVFPGKEIIQPTIVEAVSFTAWKDEAFELWNEWTK
IYDTDSISAKLITDIADNWYLINIVHNDFHDSDGIFKIFEQISVTDYEADR
>A0A2N9M0X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfotelmatomonas gaucii|TrEMBL
MQTLREKLADRTRFLVATELVSVRGPMAGASAIKVRNFANELVACPDIDWISITDNAGGN
PQLAPLVLGRPILYAGKDVVIHLTCKDLNRNGLESEAWMLHSEGFNNILAMTGDFPVTGN
DGLARPVFDLDSIGLISLLGKMNQGLGATATDGTNHQLEKTQFCIGAVTTNFKLREGEVI
PQYLKLEKKIECGAQFIINQIGFDSRKISELRGYMDAHGMKETPVIGNVYLLSPRVAQLF
HEGKIPGVVMSDELWELCGKQGGSADKGRAFFLEFAAKQIAIYRGLGFRGVYLGGAHNFA
AIEKILEIEQTFSPGDWKQFAREIQFSRQGEFFYYAEDAATGLADRGRENPRPQDSSKHV
AAVYQLSKLSHETMFVPGAIARWGAKVCAQAKDPMQGPKPLRALETVSKAVLFHCKDCGD
CSLPEIAFLCPESQCAKNQRNGPCGGTREGRCEVDGYGDCIWLRAYERLKHDGREQGLLD
HVPAIQNQGLRGTSAWANLWLGRDHTSKRKAVKAATPSSQAEQ
>D2B971|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)|TrEMBL
MTDRPFELVCEVEPPTRPDLKHVRHQIGTLSKVAHSFLIPDNHIGRATVSSVAVAHEVQE
MGGRSIACLNSRDRNLLGFRRDLLTAAAYGVDQFLFVYGDKPNSGNRTSDLTVRSMIEEV
RSLGEDPAFARTPAFRVGTAAGLRPLPAWKRAADFMFVQVSFSVEALLRWREANPVDMPV
YAGVMVIASENHARRLADAIPDIDIPAGLVERIAADRLAGVEAACEQVLRIRDSGAFDGV
HLIPVARYREVEARLSGAL
>A0A435SUZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.06.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A3P6BH61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brassica oleracea|TrEMBL
MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTA
DLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRANGIQNVLALRGDPPHGHDK
FVKVEGGFGCALDLVNHVRGKYGDYFGITVAGYPEAHPDVIGENGLASDEAYQSDLEYLK
KKVDAGADLIVTQLFYDTDVFLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEVMAALEPIQDNEEAVKAYGIHLGTEMCRKILAHGTKSLHLYTLNMEKSALAILMNL
GMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSA
SYGALTDHQFSRPRSRDKKLQQEWAVPLKSVEDIQEKFKELCLGNLKSSPWSELDGLQPE
TKIINEQLVKINSKGFLTINSQPSVNAERSDSSTVGWGGPGGYVYQKAYLEFFCSKEKLD
AVVEKCKALPSITYIAVNKGENWVSNTAQSDVNAVTWGVFPAKEIIQPTIVDPASFKVWK
DEAFETWSRSWADLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIFSVFADL
>A0A395H2F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus ibericus CBS 121593|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNYQDAQDPERDLPYL
VEKTQAGADFIMTQLTYDMEAYTKFENMLRNHESGAFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPQVLSKLEEVKHDDDAVKRIGVDIISDLVYGIRDLGCSGPRGFHFYTLNLEKT
VSFILERCELIPPYSEVDDSDALVDGGSLSAMDSSSYIAPNGAQIRKLASRRSSVSSIPH
NRVIVDKVQVSETSSKGSVTHEASALSAGLPAMPPDRSMTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVPAPIARQIWGYPVSREDISTLFRRHVSGELYMVPWS
EGGAEENSNGLNAETAVIQSELLTLIDKKGWWTLASQPAINGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPDKDYQNVLKPLFQKHGHEKLAWFATNVKGDFESSLPGPNPDDPDPIDIN
PANVNAVTWGVFRGKEIVSPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDHTK
NDVWLVCVVGQEFGAGTESGSEEEEDEKKWMWRELANSQ
>A0A3N2DLF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. BIGb0359|TrEMBL
MSFFHANQREALNQNLADLHGQINVSFEFFPPRTSEMEQTLWHSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVCLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFN
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAI
>A0A1F3B933|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium RBG_16_58_9|TrEMBL
MREIVSGSNLERLLAAGEFVVCGEMGPPQHVDKNLIAKKCDYFKGVADAVNLTDNQTAIV
RMSSVMSSVFALKGGCEPIMQMTCRDRNRLAQQSDILGAYAAGVKNILCLTGDYQSFGNQ
ADAKGVFDLDSVQLIRAVADMNQGKFMSGEEMKMPPKMFIGGAANPFAEPMDLRIIRLGK
KILAGARFIQTQPVFDMPRFEKWLTAVRNEGFDELVYVIAGVMPVKSVKALLYMKEDVPG
MSIADEYIKRMESAEDPKEEGIAICVETIKRLRRMPGVRGVHIMPVLWEAIMPRIVEEAG
LLPRPTPPPIPQVEPEAIGA
>A0A7C6F7F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MAGTRVSFEFFPPKTLQASFRLWETVQTLAPLEPEFVSVTYGAGGTTRKLTHEAVETIQK
NYGLKVAAHLTCVDATRDETLAIAESYANTGVSDIVALRGDPPGGNGKFVPHPGGFASSV
ELVEALADTGKFNIRVGAYPDRHPEARDENADVDWLKRKIDAGASSAITQFFFEAETFFR
FRDRCEKAGINAPIIPGILPIENFDGVKAFAKRCGTSVPAWLEDAFETAKRDGRHDLLAT
AVCTELCTDLMEGGVEDLHFYTLNKPQLARDVIYALGLAPEASVEKV
>A0A8G1GQ91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deefgea sp. D25|TrEMBL
MTYPLRPISFEFFPPKTDEGAAKLATTRRQLAQFNPEFFSVTFGAGGTTQEGTLRAVVDI
QAAGHSAAPHLSCVGSTKENIRSVVQQYKDHGIKHIVALRGDIPSGMGAFGEFRYANELV
TFLRQEFGDWFHIEVAAYPEFHPQSPSAEADIRNFVNKVNAGANSAITQYFFNADAYFRF
VDEVQGRGVNIPIVPGIMPIQNYSQLQRFSDMCGAEIPRWLRLRLQSYSDDTASIRAFGL
DFVTELSDRLLAGGAPGLHFYTLNAAGAVSTVCQRLGY
>B1HTR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sphaericus (strain C3-41)|TrEMBL
MRRNNNDESLKPSFYIKEGFLLYRDRGREARFMGLLERLKTHVLTADGAIGTVLYGYGLE
YCHEEMNVQRPELIEKIHREYIAAGADIIQTNTYGANAIKLARYGLESSVQRFNEAAITI
AKRAAADGGQFVLGTIGGIRGIRKSDATLNDILKTVEEQASVLLAGNPDGLLLETYYDFE
ELTATLKMLRAKTNIPIIAQVSMHEPGVLQNGMSLNIALHELEILGADIVGVNCRLGPYH
TIQAFEGVELPEKAFMSAYPNASLLDLEDGRVVYESEADYFGRAAVELRDQGVRLIGGCC
GTTPKHIAAAKKYLEELSPVSEKYAKPAKIEIVRDAEPAKYEPLHEKVKRERSVIVELDT
PRHLEIEGFLEGAKQLYEAGADVVMMADNSLASPRISNIAMGALLKSTNGVRPLTHITCR
DRNLIGLQSHLMGLNALGIHDVLAVTGDPTKVGDFPGATSVYDVSSMELIQLIKQLNEGV
SFSGKPLRKKANFSVAAAFNPNVRVLDRAVARLEKKIEHGADYFISQPVYTKEKMIEIYE
ATKHLQAPIYIGIMPVTSYKSAEFLHHEVPGIKLSEDALARMKACGEDKERATLEGIAIA
KELVEVAAQYFNGIYLITPFLRYDVTLELMKYIEQLDEQKKGVSING
>A0A0D2AHN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verruconis gallopava|TrEMBL
MHISQHLREAESSGKTSFSFEFFPPKTAQGIQNLYDRMDRMHSYGPCYIDITWGAGGRSA
HLTCEMVKTAQTAIGLETCMHLTCTDMPKSKIDEALKQAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVRYIRQQYGDYFDIGVAGYSERCDDNENVDELVDHLKEKIDEGATF
VVTQMFYDADLFLEWVKKCRKKGIKVPIVPGIMPISTYASFIRRANGPMRCHVPPSWLEA
MEPIKNDDAEVRELGRRLVADMCRKLLASGEIHNLHFYTMNLEKATRMVLEDLNLLPDVE
SPLQKPLPWRQSLGLKRKEENVRPIFWRNRARSYVSRTQDWDEFPNGRWGDARSPAFGSL
DAYGIGLKGSSEHYRKIWGEPRSVKDIADIFANYVLGKLESLPWSEAPITAEANCIRNDL
VDLNRRGILTINSQPAVDGVKSSDLIHGWGPKNGFVYQKAYLEVLVCPELIAEVITRIER
NPDMTYYAVNKVGDLKTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEFFRLGQ
DWAECHPNSSPSRYLIEDLVDTWFLLNVVDNDFHRSQGVFEIFQGLQVADIEKQVHEVKD
LPIRTNGQVNGEPTTNGQKSVTANGETRVPSAVATSD
>A0A252AZ75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter orientalis|TrEMBL
MSLSRLSVELIPRSADALREDIAAVKQLLPAADTLNIPDLMRFPLRSWDAAAQMQPLFPR
IVPHVRAIDIAPDAPLPGANQPGLEEVLVVHGDPPADLAHRTYRNSTESIIRRYKKEVPH
LRIYAAFDPYRRAPWHELEEIARKKEAGAEGFFTQPVFDLKLFDLCREWLSGETVFWGLS
PVIGPRSRSYWETTNRVVFPKDFVPTLEANITFAQTVLKSLATDKGHVYLMPLRVKLEQY
LPALQAVLS
>A0A164BS42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. TNHR37B|TrEMBL
MSTPEPASVPVSFEIYPPRTPERLPALHETIRQLASADPSFISVTFGAGGSHGGASLDVL
THILTETHVSPLAHLTCVGSTYAQAGALIREFLDAGITRFLALRGDPPAGSAEGDDFLGD
LETAAQLVQLIDRVQAERAPYSEESVPGLPGAARVAPREKVQIAVAAFPNGHPRSRHRHE
DIDALLAKQAAGATLAITQLFFHAEDYLDFVDRARTAGVVIPILPGLMPITSRSRLERVL
ELTGEARPTALAAALEQETDPRRQREVGVAAAADLVRAVVAGGAPGVHLYAFNNHETVLT
VLRDAGILLPEQEQS
>A0A3B9BTE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTHQFDLSFEFFPPKSLDASFRLWNAVETLQVFSPNFMSITYGAGGSTRDLTCSAVRVIT
ENYDVPVAGHLTCVDATKDETLSVAKGYAASGVRRIVALRGDGIKPGKEFVPARNGFSGS
LDLIRALKEIDNFDLTVAAYPNRHPDALSDSADVDHLKAKFDAGADSAITQFFFEKEDFL
RFRDKCTRAGISQPIIPGVMPIENWEKTKKFAQACAIPIPTWLEDGFRHAEAGGTERLFS
TALCAESCDDLLCEGVEGLHFFTLNDPTLTSDVCRALGRTQRHLELKAIA
>A0A356V5C3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MTTPRISFEFFPPQSLDASFKLWETVRVLAPLKPEFVSVTYGAGGTTRDLTHDAVTTIHN
NYGVNVAAHLTCVNSTRTEVLEITDGYAKAGVTDIVALRGDAPKGQDQFTTTDGGFANSI
ELVETLAETGKFNIRVGAYPEPHPDSPDTAADVDWLKRKIDAGASSAITQFFFEADTFFR
FRDACQKAGIDAPIIPGIMPITSWAGIKRFAAGCGASIPAWLNDAYEKAERDDRIELLST
AVCTELCSDLIDGGVEDLHFYTLNRPALSRDICHALGVAPSASLENVA
>A0A2D9FTY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneola sp|TrEMBL
MKVNEHIKKANGNTLFSFEVLPPLKGQNIRSLFDHMDPLMEFNPPFVDVTYHREEFVYKK
RENGLLERKTVRKRPGTVGICAAIQNHYKVDAVPHIICGGFSREDTENALIDLNFLGIDN
VLLIQGDTRKPEREFVPEPDGHAHASDLLEQVVDLNNGIYLDEELENAKPSDFCIGVAGY
PEKHFAAPNMQTDLKYLKLKQDLGADYVVTQMFFENQHYFDFVKKCRDNDITLPIIPGLK
PITSPKQLTILPQLFYVDLPMELTKEVEKCNNRDEVRQVGIEWTIQQSKELMEFGVPSLH
FYSMGKSASVYEVAKELF
>A0A2T0MK04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda pacifica|TrEMBL
MKVTEHIKKAKGETLFSFEIIPPVKGRSIQELYDNIDPLMEFNPPFIDVTTSREEYVYID
RDGLLDKKLTRMRPGTLGICASITHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFEPTRGGHRFASDLVKQVKGLNKGNYLHEVIETDNCPDFCIGVAGYP
EKHMEAPSLKSDIKRLKEKIALGADYVVTQMFFDNQKYFEFVDAAREAGIEVPIIPGIKP
IAVKRHLHLLPQVFRVDIPEDLIDAVENCKTNKDVRQVGIEWCIQQSQELKEAGVPVLHY
YSMGKSDNIKAIAKEVF
>C7M6I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga ochracea (strain ATCC 27872 / DSM 7271 / JCM 12966 / NCTC 12371 / VPI 2845)|TrEMBL
MKITDHIKKAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVEACKNNADVKQVGIEWAIQQSKELKVAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A2D4V1E9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MNRPEISFEFFPPRNIEATFRLWDTVQALAPLQPRFVSVTYGAGGTTRELTREVVATLHK
HSGLRTAAHLTCVNATREETLGIARQFKEAGVTDIVALRGDPPKGESGFTPHPDGFANSV
ELIEALRNEGDFTIRVGAYPDVHPEAATDTADVDYLKRKFDAGATEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGIFPVENWKGARRFAEACGTKIPGWVIEAFDKAERDGRQDLLAT
ALCTELCSDLIDGGVDKFHFYTLNRPELTRDVCFALGVTPEVKLEHVA
>A0A350PKN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneola sp|TrEMBL
MKITEYIKQAKGKALFSFEVLPPLKGQNIQTLFDHIDPLMEFKPPFIDVTYHREEYIYKK
RENGLLERKTVRKKPGTVGMCAAIQNHYKVDAVPHIICGGFTKEETENALIDLNFLGIDN
VLVLQGDVRKPDRQFIPEPDGHSYASELLAQVVDLNKGIYLDGEIENAMPSDFCIGVAGY
PEKHETAPNMESDLRYLKKKVDGGADYIVTQMFFDNQKYFDFVNRCREKGITIPIIPGIK
PVTTLKQITLLPQLFNIDLPEALTQELEKCTNNEAAREVGREWTIQQTKELVEFGVPSVH
FYSMGKSTSVYEVAKEIF
>A0A0T7CSK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella pertussis (strain ATCC 9797 / DSM 5571 / NCTC 10739 / 18323)|TrEMBL
MTQSTAPAFSLEFFPPRDIAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRT
LRNLGCDAAPHLSCIGATRDQLRDILAAYREQGVRRLVALRGDLPSGMGGDAGELRYASD
LVAFIRQETGDWFHIEVAAYPEMHPQAESPSADLAHFVNKVQAGADAAITQYFFNPDAYF
DFVERAQAKGVAIPIVPGIMPITNHTQLVRFSEMCGAEIPRWIRLRLAEYGDDKASIRAF
GLDVVSELCQTLLENGAPGVHFYTLNHAEATLGIWKALNA
>A0A316FLX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes xinjiangensis|TrEMBL
MALGLPSRLPGAPSVGDLVRGSAPTFSFEFFPPKTPVGEQRLWQAIRELESLRPSFVSIT
YGSGGTTRDTTVAVTERVATETTLLPMAHLTAVDHSIAELRNVIGRLAGAGISNILAVRG
DPPGDPTGEWIRHPEGVLYAEDLVRLIRESGDFSVGVAAFPYKHPRSADVESDTRAFVRK
CRAGADFAITQMFFDTDDYLRLRDRVAAEGCDTPILPGLMPVTQMATIERATKLSGAPFP
PALLPRFERLADDPEAVRALGIEMCAEMCARLLAEGVPGIHFITLNRSTATREVWQLLAS
SEVAAAA
>A0A2U1N7G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Artemisia annua|TrEMBL
MKVIEKILESTSAGSSGKVVFSFEFFPPKSEEGVENLFERMERMVAHDPTFCDITWGAGG
STAELTLEIARRMQNMVCVETMMHLTCTNMPVEKIDHALESIKKDGIQNVLALRGDPPRG
QDKFVQIQGGFACALDLVEHIRKSYGDYFGIAVAGYPEAHPEVIESNGLATPEAYQKDLE
YLKRKVDAGAEVIVTQLFYDVDNFLKFVNDCRQIGITCPIVPGIMPINNYNGFIRMTGFC
KTRIPAEITAALESIKDNEEAVRAYGIHQGTEMCKKIMASGIKTLHLYTLNNEKSALAIL
TSLGLISEAKVSRPLPWRRPTNLFRLKEDVRPIFWANRPKSYITRTIGWEQYPHGRWGDA
SNASYGALTDHQFMRPKARDKKIQEEWVVPLKKFDDISEKFMKYCLGQLKTSPWSDLDAL
QPETKIIDEQLGSINLKGFLTINSQPAVNGAKSDSPSIGWGPAGGYVYQKAYVEFFCSAE
KLNSLVEKIKAYPSLTYLAVNKEGNLLSNVGKSDVNAVTWGVFPAKEIIQPTVVDPASFL
IWKDEAFEIWSRGWAQLYPEDDSSRTLLQEVYFLLSVLAIYPRDGMVVRGIYYDLTDPED
YYGFSGMTCRTVGGYDYYNPSGWNRLDVYFGKYSIHVRLYLKGMNCVLFPITQKSITEDK
NTPFPTKVCHGARADSTRHSVLVAPWGSCFEMAPPVLAKSFLGTNMPCDDLDTSGLFYKK
VSETSNTNMVRHVPSEEIKRAMFDIGDDKAPGPDGYTSAFFKKGWDIVGQDVCNAIRDFF
GNGKLLKETNHTFLALIPKVTTPLKVTDYRPISCCNVIYKCLSKIITNRIIEGIKEVVSE
NQSAFVPGGRISDNILITQELMHNYHRDRGPPRCAFKVDIQKAYDTVDWRFLGYILKCFG
LKELIKH
>A0A7U7F9R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae subsp. pneumoniae Ecl8|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7W7Y4Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurispira natronophila|TrEMBL
MNTQSTRIAVELVPRSEDSLQRELQIVQDFPQVSAINIPDILRFDMRSWEGCALAQRGGY
ASVAHIRAIDINPKKTLPMLDYLQQNSIGEVLVIAGDIPQNHARTIYPATSVDIIRKFKK
EAPQIQVYAAIDPYRQSFRKECESMQRKLDVGADGFFTQPFFDLRLMEVYGELLAEENVY
WGVSPVLAERSQHYWETRNAAIFPQSFTPTLEWNLKFANDALSFVKRHGFHIYFMPIKTD
LRAYMQGIDFSIA
>A0A859AAI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrovum myxofaciens|TrEMBL
MNHAHYERVFSFEFFPPKTAEGAEKLRHTRRQLAQLNPAFFSVTYGAGGTTQDRTLETVV
EIQQDGYPAAPHLSCIGATRDSLRQVLALYRHHGIRHLVALRGDLPSGTLGGGEFRYASD
LVRFVREETGDHFFIEVAAYPEVHPQAHSAQEGIRHFQEKVEAGADSAITQYFYNPDAYF
SFVEDCGAAGITVPIVPGIMPIANFSQLSRFSDACGAEIPRWIRQKMQGYGDDSASIKAF
GLEVVTHLCDRLLEGGAPGLHFYTMNSAGLTSVIWERLHLT
>A0A7S4UE63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Guillardia theta|TrEMBL
MESGKRAIETLVAAKAVCSLDVQMHMSCTGITKKMADDLLVEAMDADIRSILVLRGDPAP
GKSDWEPVADGFKNASELVSYIRHKYGDFFSLSVAGHPGKHPASSSKEEDLEHLKQKVGC
GADFIITQMTFKASEYQEFVGSCRRVGIDCPIIPGVLMIPPSLEKLRAVCNHCSVEVPED
LVELLETCGSDKEKVREAGRVYMQRVCSEMLSSGAPGLYMYTLNLEKSAQEIVTNLNLKV
LDAGMSDSAVRPLPFPRPREKETVRPIFWASNAISYLTRTRNWSADFPSQWGQVNNEKSK
AGDHSFVYDPLPSGDEDNILYSHHSIVGRRLGSMAERRNMWGESPSTEEDVFDVFERFVR
GFVPRLPWCDRLEKETLASGILKPLATLNHYGYLTINSQPRVNGAPSEDEQFGWGPRGGH
VYQKAYLEFFCSPGNLDRLLEALGSHPSISLEAFNVNGGRRCVWTDSLGQRNKTDEANVN
DDRHISAVTWGVFDGSEVTVPSPLPTLHLIFSFYRSSNPPSWTPSAFRFGARKRWTCGRV
CGPPSTPSDQNPEA
>A0A1V0RDI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter helveticus|TrEMBL
MCSFSFEVFPPRRDETIKNLDAILEDLGRLSPNFISVTFGAGGSINSQNTLEVASLIQEK
YQIPSIVHLPCIHSSKEKITAILKECKQRGLNKILALRGDVCEGLEKSKDFSYANDLISF
IKKQENFEIYAACYPEKHSEAKNIIEDIHHLKNKVNVGTDKLITQLFYDNEDFYAFKQNC
ALSGIKVPIYAGIMPITNKRQILKISQLCGAKIPTKFTKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKTKAAIRIYEAVKHLPKEENEAKNVL
>A0A4Y3TVG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter peroxydans|TrEMBL
MSLARLSVELVPRTPEDLINEARTVKTLFPAADTLNIPDLMRFPLRSWDAAKLAQPYCKR
VIAHVRAIDIAPDAPLPGANQPGLEEVLVVHGDLPADLSRRTYPNSSESVIRRYRREAPH
LRVYAAFDPYRRAPWQELEDVARKKDAGAEGFFTQPVFDFKLFDLCREWLKNETVFWGLS
PVIGPRSRSYWETTNHIVFPHDFDPTLEANVAFAGRVLRELSHTQGNAYLMPVRIKLEQY
LPPLLAWLD
>A0A2M7H508|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kerfeldbacteria bacterium CG15_BIG_FIL_POST_REV_8_21_14_020_45_12|TrEMBL
MSDSSRQETSNFLDHLEGPEFTVSVQLDPGSDGATHDLHHLLDAIRVKGGIQAVDINSTS
SRAAWDAVMTACAVQARGMVAVPHLTCRDASFGGIVNQVLAGVTHFGLQTVLAVTGDRPK
RSFPQCRDGVFQGDAVALVAALDELRRGRHRPGKEQAPTRFAIGVAFDYTLSGSALIREQ
DRLRAKLDYRANFIMAQPIFTVGHAGNLAARPSRAG
>H0QSX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter globiformis NBRC 12137|TrEMBL
MTNQMPLRLEIIPTDSIIPKVQAHVPAGSTLTVTCLPHHGVGTTVRASVQLAQLGYKVIP
HLAARSIESRVQLAGMLRDCEAAGITEVFAIGGDAPEAAGPYGTSSRLMEDIADLTGGTM
AIGVAGYPEGHPKHNELTMLDALLEKQHLASNVVTQMCFSAPRIGWYAELLRREGVDLPV
WAGVAGAVPRAKLVSLAAKIGVGPSLKFLSRKGPLARRLLNAGSYSSRFLVSELAAMEPA
LAGIHLYTFNNVETQPATNWRAGEGAKAS
>A0A085JNB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tatumella ptyseos ATCC 33301|TrEMBL
MSFFHANQHEALNQSLSELNGRINVSFEFFPPRTQDMEDILWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDANRDELRSIAQDYWDNGIRHIVALRGD
FPNGVGKPDMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLLSLKRKVDAGADRA
ITQFFFDVESYLRFRDRCAATGIDVEIVPGILPVSNFKQLQRFATLTNVRVPNWMNTMFD
GLDNDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPQLAAV
>A0A4R0CVT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium pisi|TrEMBL
MAMSQAIHLRDQSDVLDDFSVEVTTKDTAQLAAMSGAIPKGTIISIPFLSTESDADRIRA
AKMVRQAGYVPLPHIAARRLGSESMLSAMLSALVNDAQVSRLLLVAGDADPPKGPFLDTA
TILRSGILEQHGISNVSIAGHPEGHPVQNAAMLTSALLEKRLIMEAANIEWSIFTQFAFA
SEPVLAWIGELRRLGIEVPIHIGIPGPASVRTLLKFAAVCGVSASTSVLKKYGLSITQLL
SSAGPDALVNEYATGLSNAEYGDVRLHFYPFGGLHKTVDWLQEYRTRHS
>A0A0S7ZHR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium DG_61|TrEMBL
MGFRDALRTDKFLITMDTIPPKGTDISGVLKRMSSLKGRVDGVNVVDMPSAVMRMSPLPL
SYLINKKGFEPILQITCRDRNQLSLQAEFLSASVLGIHNFLLLTGDNIELSDDPNAKPVF
ELDSVKLLRAARGLEQDHHLTTGTLSCSPDFCLGAALDPGADPLEAEIEKMEKKISAGAE
FFQTQPVYDVNKFTDFMKKFADLKTPILAGILLLKSAKMARYISENVPGINVPDDIINEM
SKAKDPIGKSVEIAVRTIKSLIGVSKGVHIMTIEWEDKVPLILDALE
>A0A0B1P5E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Uncinula necator|TrEMBL
MEKITDKIAALPHGSNYFSLEFFPPKTIMGVSNLRTRLSRMSQALKPLFVTVTWGTGGST
AANSLELAELCQRELGLTTCLHLTCTNSSPNVIDEALKKAHELGIRNILALRGDPPRKEY
MSADLEMEESKKFEWAIDLVKYIKKKYGNYFCVGVAAYPEGHADGNHPDSQSFEHDLPYL
VEKVKAGADFIMTQLFFDTDAYDVFERRLREHESGCFEMIPIIPGLMPIQSYQMIKRIAK
LTHVKIPPKIAARLDTTIGDDELSKEVGVDIVSEIILHIQQNPLPALGRRGFHLYTLNLE
KAVSLIIERTSLIPSTSSTIGDNSEPEYVIVDKPVLTPTEINTLAHSCKGQHQQNLNLLN
PNTNTAMKKSSSFFDVASPDIDTLLNSSTISASNLVRTKNIGSLGREATWDDFPNGRWGD
VRSPAYGEIDGYGVSLHVSVKQAIHLWGYPQSKDDITSIFVKHVNGSLILIPWSDEGLYR
ESDVIKDQLLKLNKKGYWTIASQPAINGIRSSDSTFGWGPRNGFVFQKEFVEFFILSKDW
ESLKIKLQFTSITRNISWFASDSKGNFLSSGTNEELGLKNKEYPGNVNAVTWGVFPGKEI
ITPTIIEEVSFRTWAEEAFGIWAEWAKVYINGGPYLTDASREAARRSHRLIESVREEIWL
VNIIHHGFNEKDSLWNFLLG
>A0A255Z0L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niveispirillum lacus|TrEMBL
MSLSDLMDAAANPAPLITAPGDLTVSFEFFPPKTEKMHENLWTAIRRLAPLNPAFMSVTY
GAGGSTRERTHATVTAIQAETGIPAAAHLTCVAATKEEIDEIARSYWDAGIRHIVALRGD
PPPRADGTGGLGGRGYEPHPGGYAYAADLVAGLKRIGDFDISVACFPEVHPEAPSAQIDL
DNLKRKVDAGANRAISQFFFDVDAFLRFRDKAADAGIHVPMVPGILPILNFTKAAEMGEK
CNTAIPVWMRDLFDGLDEAPETRHLVAATVAIEQCRYLEKHGVKQFHFYTMNRADLTVAI
CHMLGVRAAKG
>A0A2N2VV90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-7|TrEMBL
MTVLEKIQTAKSPLFTFELLPPLKGHSIDKVYTAIEGLLEFQPAYINFTSHRNETTYRER
PDGSLEKRVARIRPGTIALAAAVKYKYDITVVPHVLCGGFTREETENALIEMNFLGIHDV
LALRGDPVRGSRSFIPEKDGHANAAGLVKQIANLNRGKYLDESMEHAAPTSFCIGVAGYP
EKHFEAPNMEADIALLKAKVDQGAHYIVTQMFFDNAKFFRFVEACRGAGIEVPIIAGLKP
ISALNDIRLLPQTFHIDVPNDLYKAVAACRDDAGAREVGVEWATAQSRELLKAGVPGIHY
YTLGRSDNVAGIVRGSF
>A0A8D9ZFX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus subsp. aureus WW2703/97|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A8J8WE54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosopumilus sp. b2|TrEMBL
MTIRYEANPPKILPDVNTDESIKKFVDRIKIISKKCDAIHLTENVLGYQRASPLDVGKII
KNEMPNLPITVSLRVRDKTEEEISDFVEKCIDIGFSGILILMGDPSQTGKKDSGQIPSLT
VKKLRERNIDSKIDLYLSVPNKPNFSKLEKKFDAKPKGFMTQVVQNVKQVQELSNNLKGF
AVIPIILFPSQKNEKSAAFLNLDLESYSQEFEELLKKAHEITGDILITSPNDFSGLNEFL
NEFAI
>A0A401ZRZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyobacter aurantiacus|TrEMBL
MQRHNPFLERLRNGPLLCDGGMGTELYARGISYERCFEHLNITDPELIKSIHLDYVAAGA
QIIETNTFGANRYRLAEHGLENRVVEINRAGAKIAREVRELSEQPIFLAGDIGPLGSPLA
PIGTIQPADARAAFVEQTEALLQSGVDLLIIETMSDLAEMREALMAVRSVTDLPVVALMT
FGEDGTIVSGEDAHTVATTLRDLGANIFGVNCALGPASMFDVAKSMCGYSTDDFFVAVQP
NAGLPRRVGNRFIYVATPEYFAEYTRRFLGIGVRMIGGCCGTTPRHIAAMHEVLNELAPT
IAPEDDTQSSTTTLEALRERMQENAAQGQEEQPVTQLAARLQEGRFVISVEMSPPRSVKF
TRFLQNATFICENGADTINITDNAMARVRMNNVAAARLIQQNVGIETIVHFTPRDRNLMA
VQSDVIGAHATDIRNILAVTGDPPSHGDFPNSTGIWDVDSIGLISILNNLNKGLDGNRRK
LAASSSFFIGCAANPAATDLDLELERLQRKIAGGAQYIMTQPVFDAGAFLHFINRYKDQY
GEIPIPLLVGLQPLHSYQQAEKFHNEVPGIVIPEEVRHRLRQAGDAGGAVGIEIIKELFD
KLYPLVQGAYIMPLDRFELVGELIPYIRQQTTKA
>A0A845GWL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rugamonas sp. FT81W|TrEMBL
MANHNFSIEFFPPKTAEGAEKLRVTRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILA
AGEDAAPHLSCVGGTRESIREILTEFKAHNIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGEWFHIEVAAYPEVHPQAKSPQDDLLAFERKIKAGANAAITQYFYNADAYFQFVE
QTRKIGIDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTALCERLLAGGAPGLHFYSMNQAAATTALWQRLV
>A0A0F3HB22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus infantis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIIAALKDMQDLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKDQAPHFEIIGACYPEGHPDSPNQISDIQNLKRKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQSLG
>A0A502HDI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas arsenicoxydans|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGNHFHIEVAAYPEMHPQARNFEDDIANFVRKANAGADSAITQYFFNADSYFY
FVERVRAAGVTIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQSFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A5S3NAL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter aestuariivivens|TrEMBL
MKITEHIQKANGKTLFSFEIIPPKKGNNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYVLVDCHYLGIDN
VMALRGDAMSHQKYFKPNEGGNVYATDLVKQIQNLNCGKYLHDVIEASNKADFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYIVTQMFFDNKKYFEFVEAAKNIGINVPIIPGIK
PIAVKRHLQLLPQVFKIDLPENLISSVENCKTNKDVRQIGIEWAIQQSKELLAAGVPVLH
YYSMGKSDNIHAIASELF
>A0A367YLX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida viswanathii|TrEMBL
MATVSERISSLKPDERFVSFEFFPPKTDSGFRNLLARLNRMLAFNPLFITITWGAGGSTS
EKSLDLAATCQKEVGITTVLHLTCTNTNKEIIDEALARAKANGIRNILALRGDPPRAEEY
WTPNCDFNSAVDLVKYIRQQYGDYFCIGVAAYPEGHVDGADTSGQDPKKDIPFLIEKIKA
GGDFIVTQLFYDVDKFIAFEKLTQEHEELKNVPLIPGLMPITTYKVFNRAAKLSHASIPR
EISQQVDRVSNDDDAVKALGVEILSDIIDKIDRETRIKGYHFYTLNLEKAVASILDKSKV
LRPILDGPSSVVEHEDAIASDSEDEEETPSTAVSRRRSSVNDNILNGAKVLVGKTLLKDK
KVLVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPTLKIHSPAEAEIKWGSP
ESVGDLAQIFIDYLSGKIDVIPWTDQTLSPETALIQEELFLLNEKGWFSVASQPATNACK
STDNIFGWGPRNGVVYQKAFVELFMPKEDWQKLEPLVKASDSITYYIGDKTNKIETEVPI
GHNARLSKNAVTWGVFPLKEVVQPTVIDYESFKAWTEEAFLLWLEWSRCYKKSSKSFELL
NNVYENYVLVCLIHHDYPEEHALWDFLLDE
>A0A1I4YQQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dokdonella immobilis|TrEMBL
MTAISFEFFPPKTDEQREALEKSVRLLKTADPEYVSMTFGAGGSTLSHTVEAVRGLRADH
GLDAAPHLSCMGGSRAEIRALLEDYLALGVGRIVALRGDLPSGMASVGDFRYASDLVAFI
RSETGDHFHIEVACYPEVHPQANDAHADLAHFKRKIEAGANGAITQYFYNADGYFRFVDA
IRALGVDVPVVPGIMPIANFSQLRRFSDLCGAEIPRWLAKRLSAFGDDATAIRDFSADVV
ADLCRRLIEGGAPGLHFYTLNRARPTLAILERLGQDNALSRHL
>A0A0H3Q387|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cholerae B33|TrEMBL
MTLGHREYKMGYTHASHIDALNQNIAELSDINVSFEFFPPSSPQMEETLWGSVHRLKTLQ
PKFVSVTYGANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQ
NIVALRGDIPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRK
VDAGANRAITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVP
NWMVKQFEGLEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGV
RPQA
>A0A1F7LGP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium GWA2_70_23|TrEMBL
MSNPLAVALRAGRFVHVVELVASRLRREAQVLDVAGRLAGLPEVVAGSITSYAGGAIGHD
PIRVGTAARARGLAPNIHLTCVSQDRQGLRKILEDLHALGIENVFALSGDYPQGSDPGQP
PPVFDLDSVQLVRMIADMRRAGMSFHISVAVSPFKYVEADCVYQYLKLEKKIAAGADLAI
TQVGWDARKFLELKRYLDQRGLRTPVLGNVYVLGKRPAERMAGGQPPGCWVSPALLAAVR
EESAARDGGRRARLERAARTVAVLRGLGYAGAYIGGTHDAEEVDGIVRRGLELAPRWEEL
AAELSYGAPDGFYLYAETSGSGRGAPAPSSTASTTITGLGGDRGPAARPASGSRAALPRV
LDALGRLVPVDRDTLARRGLTSVFRWVDRRPGVAHALERAELLVKRPLFGCQACGSCVLG
HLEYVCPQTCPKQMRNGPCGGAALGRCEVLDRPCIWVGVYERARATGRVDDLRGYIPPPD
RSLQGTSSWINYFLERDSRPAR
>A0A7W9D0Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium paranaense|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERASIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRMMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFRDYMKKVRDLGLHEKCFVMVGV
GPLASAKTARWMRSNVPGVHIPDEVIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKHEASRTDALVAERLEHIRGGMEENQQQMAEAAA
HHPPHLAH
>A0A0C9P0Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei NRIC 0644|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDGFDMEPVAHLPAAQLTRKQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A1G0GJH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_38_14|TrEMBL
MKKLNSVSFEFFPPKTEESQGHLLAEALNLSGIEPHFFSVTYGAGGSTRDKTINTVRLLQ
QTTSIPVAPHISCIGSKREMLIEILSAYKSLGVKRIVALRGDRPADDFQQGDLSYAYELV
QLIRDVTNDAFFIEVAAYPECHPEAKSTKEDILNLRKKVDAGANSAITQYFYNPDAYAYF
LDECSKAGILIPIVPGIMPIMSLNKLIRFSNLCGAEIPKWLLKRLENYGDDTASLQAFSL
EVVFKLCERLVEYGANSLHFYTLNQAEPSMTLVKQMMAKKYKILGSSLDRHPERSEGSL
>A0A415RNW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprobacillus sp. AF33-1AC|TrEMBL
MKINNLLNKRPTLSFEIFPPKNHGDDLSSIFLTISQLAKLNPDFISVTYGAGGSTSKNTA
KIASIIKNQYHIEAVAHLSCIDTSKEDLIDILNELKDNNIENILALRGDYPQDYDQRDLQ
GDFKYASDLNEFISEQFPDQFCLSGACYPETHFEAESFEQDLQNLKKKVDAGAKYLVTQL
FFDNQYYYRLIKRARQIGINVPIIAGIMPATSSKQLKRLSKISDCSIPYSLASMMERFLD
DPEACKEVGLHYATYQIIDLMSQGVDGIHIYTMNKPEIAEEILKRTKAIRREYFKD
>A0A3S0KTZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. C 49-2|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQAHSFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISTMCEDLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A4U7N6K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagicola litoralis|TrEMBL
MNQPTISFEFFPPQNLEASFRLWDTVQTLAPLDPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNATRAETLAIANDFAAAGVSDIVALRGDPPKGSQSFQAHPEGFANSV
ELIEALAQAGNFNIRVGAYPDKHPEAENTQADIDWLKRKIDAGATEALTQFFFEADTFLR
FRDACVKAGIDAPIVPGILPIENWKGARNFAMRCGTDIPAWLDEAFTKADRDGRTDLLAT
AICAELCSDLLDEGVDSLHFYTLNRPELTRDVCHALGVTPKILLENVA
>A0A2S4YVK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ru71|TrEMBL
MALGTASTRTDRARTVRDILATGKKTYSFEFTSPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTTTVKETQQIVVDTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFHPESYLRLRDSVAAAGCETPVIPEVLPVTSVKMLERLPQLSTAAV
PDELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A427P253|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cenocepacia|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNLATATRTICERLAM
>A0A0N5AQB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syphacia muris|TrEMBL
MANNMQSNKTCEKASFGRKTAFSAYVPLHKRIQNHINDGTPFFSLEFFPPKSVNGVANFF
ARIDHFREGNPMFIDVTWHLGSDPGNITKETSSSSIAAGCLNYCGMETMLHITCAQYSKE
QTLRHLDQSKAVGLRNILALRGDLPQNSGTKVIPRFRALDMIRWIKEEYGDYFTIGCSGY
PTGHPEAPSYKADIQYLKMKVDAGAQLVITQLFFEAEEFENFVKDCRSIGITVPIIPGIM
PIQSYESIRRIASLSQLTIPDWILKKLEPIKQNDDAVRKYGIHCAVELCKRLLSNGSAPA
IHLYTMNREAPCREILQTLGLWIEIPQRALPWRSFGCNHPLRCREDVRPIFWSTRPKAYV
FRTRDWDEYPNGRWGNSSSPAFNDLADYYLFSLKGLPTKDEQLRMYGYSVENFEAVKKVF
VNFITQDLNENEVKVTRLPWNEQEIGTDPETSIIKDHLIWCNQNGILTINSQPAVNGAPS
TDPLVGWGNPGGYCYQRAYLEFFTSKENADVLRKLLETESRLSCQITNHDGTIDWTNAES
TTPIAVTWGVFPGMEIAQPTIVDPLSFHVWKDEAFAAWLNWASVYPENSKSREVLQQIHD
GFCLVTLVDNDYPKPTVIFDILKQMVAHN
>A0A8J7X7Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeota archaeon|TrEMBL
MSTFSKKIGKKFIYTTEVKPPRGTNTKPFIDEIKAIKKIKGLTSVNVIDSPSARLFMSSL
GASIMLEKHGLEPIFQMVCRDRNSLALESDLISASAFGIENILSLTGDHPQRGASDHPKT
QPVFELDSTTLIKTITLMNQGTNLMGQELDGKTNFFVGAALSPSSTPSEPEILKTKRKMD
AGARFFQTQAVFQVKTVEEFFDKSDKILGDIRPVVLAGTIPLVSEKMIAFLNRLPGIRVP
EDVASRIAKSKDPVEEGISMTMDLIDGIKSQGLGGVHIMPVGRIGSLRKIMDSI
>A0A3C1AG04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPDFFSCTYGAGGSTRDRTLNTVLQLE
SQVQVPAAPHLSCVGDTKAELRALLAEYKQVGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETGDHFHLEVAAYPEMHPQARNFEADLANFAHKVKAGADSAITQYFFNADSYFY
FVERTQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEELLQGGAPSLHFYTLNQAEPSMAIWNNLQSSR
>A0A3B8P4B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
HEVKVPAAPHLSCVGDTKQELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQARNFEADLRNFVHKVKAGADSAITQYFFNADSYFY
FVERVQQMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQADASLSIWKNLNLPR
>A0A1I1CS69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia tsuruhatensis|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A4R5IQR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp. L7L|TrEMBL
MQDRYFSFEFFPPKTAEGLEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYREGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVKAGADSAITQYFYNADAYFRFVD
DVRAQGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAAATKAIWQRLKL
>A0A1E7J932|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium C00003063|TrEMBL
MAVSSECGPPRSSDPAHIIEKGHLIKNHVDCINITDNQTSVTRLCSLAACIHLKQEGLEP
VLQMVVRDRNRIALQSDILGAASHGIHSMLCLSGDHQRFGDSPEGQNVFDIDSMQLLQTV
RYMRDEGKFLGGDAIKVPPNMFVGAAANPFADPFEIRVPRLAKKIAAGAEFIQTQCVYNL
DKFELWMKGVVERGLHEKVFIMPGITPMRSVGMAKYMARAVPGMDVPKELIDRLSGVPKD
KQSEEGITIAVEAMERLKECTGVAGFHIMAIEWEEKVPEMVERAGFYPRPEFD
>A0A0D8I7R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium aceticum|TrEMBL
MKVTEIMKKKMSFSFEVFPPKSEQPLEPLLDTLEHLYKFNPDFVSCTYGAGGSNAGRNME
ICKAIKDSGKSIPVTHYTCIGNTKEKIREELETYLAMGVDHILALRGDFPKGWEGTRGDF
NYANELVAYIKNNFPEFTIAVAGNPEKHFEAASFDADITHLRMKQDAGGDYIMTQLCHDV
DQYSWWVERIRKAGITMPIDVGIMPVLSKDPTIRMAVSNGSAVPRDLAEIIGRYGDNPDD
FKKAGKEYTVKQIHKYINAGIDGLHIYSLNRWKDVSDIIQAAGLR
>A0A1I8F9H2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macrostomum lignano|TrEMBL
MPENSSSVAKMPAKEKLQQEEQERRSPPTSRQYRPLATRIRRRIEKGRRWFSCEFFPPRK
HPGGRCEPRLQVRQLRQGRGRCSATSPGTGRRNPAGDSPTSSTSTEARLVRVLDRAKSLG
LKNILALRGDLPEDADGNPGGASAAAIGGPAFASDLVRLIRRRYGSFFCIGVAGYPAGHP
GRPPATREDLRRLKEKVDAGGRVHHHAAVLRVGRLPPLRVRLRRVGIDCPIIPGVLPLSK
LTVPDSMLRVIEPIRDNDEAIRNLRHRAVHADVPGASGRAPGIHSTRLNPGRGEPSRILR
EHRALARGSASAVAMATVRNYERCAEAVRTRVLVPAAHQLRAPDAGTGMTIPTAGGAPSF
RASKQERLRMWGSEPTSEPDIWRVLRQPPVRETSQPGRCPSHRLPWGDEEPLPSSSESRR
GGEGAAAAGRSERARPAGATNPPAAGERRQQRPPGGTAGAAPAASCIQRAYLEFFLPGCR
LPALQCGTEQPRWRRVSFHIARPVGNVNLANFSEPIALTWGVFPASEVAQPTVCDGGRLP
GLGGTRPSPLWTEEWAPVRGGLAEPPPDRQCRGQPRAITKSDGQAGDTRWRSPARIRRRG
LRAPEAEGGWPDFDCATGLFAEMFNGERLQESHRHPASPAAAPESGRSAAMSAAVSLGTT
QGADVLVQLLGAELARQQQHAAGVALRTHQAMASWASVQSRWVAHLGELLELWPVCCRAL
LAEDFIAQPGVADISTKAGTAELYLKHCT
>A0A2C8YBH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. D7|TrEMBL
MKPIELSFEFFPPKTQEGIEKLRATGAQLKTLNPKFVSVTFGAGGSTQQGTLDTVVEMMK
QGLEAAPHLSCIGSSKESLRAILGAYREHGIRHIVALRGDLPSGMGEVGELRYASELVGF
IRAEHGDWFNIEVAAYPEYHPQARSPKSDLENFVRKVQAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPKWIARRLESYGDDKDAIRAFGLDV
VTGLCERLVKEGAPGLHFYTLNGAAASKTICERLALPKA
>A0A1Q6JJI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium 41_21_two_genomes|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPD
AMKQAGIAYATDQIIDLLANGVNNIHIYSMNKPEIAVAIMNNLSEIIKC
>A0A2P7BHM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium sophorae|TrEMBL
MTKIAASIEVAARQAIESQDLPGLFPAGTRVYITDMGTDSVDTLTSAAKRIHDLGYKPVP
HFASRRLSTKAALETRIRRAAQEAGVTDVLVIGGGLERQAGEFSSTMEVLETGFFDKYGI
TEMGVAGHPEGSPEFSEAVAIEALRLKKNFGERTGAKLRVVTQFGFDADRFIRYSESLRE
HGVDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNALSLTALATSHSPEGVVGPIE
QHAIANPASAIKQIHIFPFGGLKKSSEWLVDRGSWKVHNASHTSANAAAS
>A0A849S447|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium|TrEMBL
MTTQSPLFSFEFYPPKTEEGAENLHLVHSKLAQLNPDFFSVTFGAGGSTRDKTFDTVVGI
QAKGIAAAPHLSCVASTKDNIRQILKDYQDHGIARIVALRGDIPSGMMSAGEFRYANELV
DFIRQETGDYFQIHVAAYPEVHPQASNASEDFKNFKRKVDAGANAAITQYFYNAEAYFYF
QDNCAKHGIDIPIVPGIMPITQYAQLFRFSEMCGADIPRWMRKRLESFGDDRDSVQAFGL
DLVSKLCQRLLDNGAPGLHFYTMNQSAPTLAILDNISH
>A0A2A8V778|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS015896|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAMKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMAPKFIEQGVRLLGGCCGTTPEHIECMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIN
LPEAIRERMDGHETKEAAIEEGIHISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A5N9AKL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MKISNYYDLAQTTISFELFPPRTDKSARDLEERLPRLISLEPSFITVTYGAFGSDQNRTL
EIASKIRNEYQMDVAHHMTCVSSSKEDIDQLLAQIKENNIDNIVALRGDKPETSNIFSPP
ENGFSHANELVAYIREYGDFGLAVAGYPEKHIEAEDFETDLFYLKKKVDAGADVIITQLY
YDNDHFYDFLTKCRDIGIDVPIIPGLMPILNLEQIKRITRICGATIPRDLLAKLEDAKDD
PDKLHEVGIEHTTNQALNLIQNGVTGIHFYVLNRYFHIAEIMERIKPALQN
>A0A249NU79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. CCBAU 05631|TrEMBL
MSPDINPFDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PMASAKTARWIRSNVPGIHIPDSIITRLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKHEATPTETLVAERLEHLRGGIEENQQQMAEAAAH
HPH
>A0A5M4EWU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MQPSGSASQHLSAMLENTDRFLTTVEIETSRGILMGEDSRKTMDSAQSLAEFDRVDFVSL
TDNPGGNPHIRPEVLGQELLSRGREVMINLSCKDYNRNSVESRLWALDSQGFSNVLALSG
DYPVGGFEGQAQPVFDIDSVGLIEMMAQMNEGLRNKALGSSSSGHRLEETNFFTGCVVSP
FKKLEGELMTQYFKLALKLRTGAKFAVTQIGYDSRKASEIHNYVESNGINVPLIGSVFIL
TAPAGRFFNRWGVPGVCVSDNLRDIANR
>A0A259PH40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. 14-74-6|TrEMBL
MSVADARTAASGPVVAPVDRPTVSFELFPPRNPDAAPKLWDTIRRLEAVRPDFVSVTYGA
SGRTRTTSRALVRRMLHETTLTPIAHLTCVGASRGEISTIVREFLDEGVRSFLALRGDPP
EGEAQWQAHPHGLTTASQLVELLREIEHERCEQSPAQAVRARVKPLSIAVAAFPRGNRLT
GSSREQDIQALLAKQRAGADFAITQVFYDADSYLELVGEARRAGVVIPIVPGLIPATDPA
RLVRTEQVTGVPVPPDLLALLDEADDEAERRRRGLRFGIELIDRVLEGGAPGIHLYTFNK
HEAALDLLEGAGLVGRPTATTTARTDA
>A0A5W8MDD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Hofit|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A455UWU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas axialensis|TrEMBL
MALRGDMPSGMASIGELRYANELVEFIRDETGDHFDIAVAAYPESHPQAPSLDKDVENFA
RKMNAGANMAITQYFFTADAYFHFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAE
IPRWIRKQLEAYGDDSDAIAAFGTDVVTRLCERLLDGGAPGLHFYTLNQAAPVLKVVDNL
S
>A0A1G6YSS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus isoporae|TrEMBL
MPTPNVSFEFFPPRNLDASFRLWETAGALAPLAPEFVSVTYGAGGTTRQLTHEAVTALSD
HYGLNVAAHLTCVNASREETLQIVDEYAASGVREIVALRGDAPKGEDRWTAHPDGFASSV
ELIEAIAARGDITIRAGAYPEPHPDSGGSSNADVAFLKRKMDAGASSAITQFFFDADTFF
RFRDACVAAGIDAPVLPGILPIQSWTGARKFAERCGTSVPGWAVEAFERAGKEGEAALAR
NLCVTLCRDLLDGGVEHLHFYTLNRPELTLAVCEDLGVERTGLAA
>A0A3D3ME84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQINDLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A1Q3E216|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentinula edodes|TrEMBL
MKVTQKIAQCERENKIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
ELTAEMVKTCQGLVGIETCMHLTCTNMPKEKVDIALREAKVSGCRNVLALRGDPPMGKEE
WEAVEGGFVHGIDLVRHIRREYGDYFDIAVAGFPQHQTLPPEERDLEMRYLKEKVDAGVN
FIFTQMFYDVDVFIDWVNTVRAAGITIPIVPGIAPIQTWNGFQRATSLAQTIIPQTFQDA
LEPHKANDEKVREIGTKLVADMCRRILNANLGIHGLHFYTMNLEKGTRMLLEELNLVPRV
ETIKPLPWRQSLTPTRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVSIKQSREDALKLWGQPSTFAEIADLFAQFCIGKLSALPWSDQKPSTETSIISEQLA
RMNSLGFLTINSQPAVNGAKSSDKVFGWGPRNGYVYQKAYLEFFVKPALLTLLLSHIERD
SNITYYVINKRGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGQQ
WARVYDPDSPSAKIISELMDSCYLVNVVHNDFHDAGAIFKPFFQAGEEYATQANGH
>A0A0X2NKI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium variabile|TrEMBL
MPPRDDAAEARLWSAAEAFHDLGASFVSVTYGAGGSSRSRTERVAGRLAVKPLTTLLHMT
LVGHTEEELRGILREFASLGLTNLLALRGDPPGDPTGEWQGIAGGLSHAVHLIELVRSMP
ECEDFDMGIASFPEGHYRAESIEADTRYTVEKLRAGANYSITQMFFNVDHYLRLRDRLAA
CDPVHGAKPVIPGLMPITSLRSVRRQVELAGCELPRDMEELFTKVADGDERKNAAAIREV
GIEVTTKMAERLIAEGAPDLHFMTMNNVRATQEVLHNLGMAPAYGPKFGQDMVR
>A0A1Q7TFC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium 13_1_20CM_4_54_11|TrEMBL
MHITDIMRGDSPTFSFEFFPPKTAQAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
GLVERIQHTTKLDPIPHLTCVCHNEEEIEAILLRYAQSAIGNVLALGGDRPVGIAYDKAR
DSFQHAIDLVKFIRRFNESGAHPDRRGFGIGVAGFPEGHPATPNRLLEMDHFKAKVDAGA
NYIVTQLFFDNRDFLDFRERCALVDINIPIIAGIMPITTLNGFKRIAELAGGARFPARLL
RALQRCQNDPEMVRRVGLHFAIEQCHDLLDNDVAGIHFYTLNRSDATRMIFDSLGIPRRR
NAEPSSV
>A0A1H1PHI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microlunatus soli|TrEMBL
MAVNTTPSTPPTAAGEATPLRTPTIAELLAQRTRPLFSFELYPPRNEEEERRAWFTVRRL
EQLQPDFVSVTYGASGSTRDRTIKITEQIAETTTLRTMAHLTAASQSRTELRRVIGSYAA
AGIRHVLAVRGDMPGGPTVPWERHPEGLANATELVATVKELGDFCIGVGAFPDVHPQAAD
ADLDARILKAKADAGADFAITQLFFTPARYFEMVDRVRSLGCDIPIIPGIQPVTRISQIQ
RFAELSGAALPAPVVARLEAVGDDPKAVRKVGVEIAAEIAEEVLAGGAPGAHLYTMNRSL
ATREVYARLRSEFGRA
>A0A558I3T0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoalteromonas elyakovii|TrEMBL
MALSLKEKIVDTNQGVYLIGTTPPKIGTDKAQLKTIAEKLLGRLHEIEYDGVIIYDIQDE
SSRTNQDRPFAFKQTVDPREYSHLLRNLSAQDVITYKSVAQRGVGEFKDWLSETKNDYDL
QNVVLVGSPSSIGDIKLSLPDAYKALAEQSDDFFLGGVTIAERHSSKRNEHERLIEKTAQ
GCQFFISQAVYDAQATIELITSYARTCKAQGITPQRIILTFTPCGGEKTLEFMQWLGISV
PEATKWRMLDADNTLSESVRICRENLDLILKSCAHLDVPLGLNIESLTNRKEEIDASINL
YRLLKAIMELNLAEKLIA
>A0A5N8ZGJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MHDLIEAYRKSNKPLLLCDYSPPRSPGAMNLDSLKKLPVDYFSVAYNPGKAPRVDSITAA
RLIQSVTSKPXIFTMAARDMNKIAIQSQLLGASISDLNNVLLVGGDPLAELEKKNGATEV
RDYKPTDLIRSTAQLALGLDYRGMKIAEPPVFCIGAALDTSNNLDLEIPLMLTKIQAGAQ
FFITQPIYEINEYYGFLEKFKSITGSDLTVPIFWGLQVLSSDGPIFGKPTQRVLNNLNYK
INPLRIARDLLQDMRSAEVKGIYLIPPISSNGRRDYPSLNDVIYA
>A0A8J5KTK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MAAEENHREGELVSNLETTTTFETGHVLGVLLASSPLLEQAWTRCLRANAGSASFVIDKS
DGAVFIPFSRAQAPASPSGLGRGFFEPVSLYSSTHKLFALLGRGKEDSGGKSQPVLLQVC
METIMHLTCMNMPLEKIDHALNTIKANGIQNVLALKGDPPHGQDKFVQVAGGFACTLDLV
QHIRAKYGDYFGITVAGSAIREA
>A0A8E1RJT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus kefiri DSM 20587 = JCM 5818|TrEMBL
MSLTELFKTKTVFSLEVFPPKKSSPTEAILPTLKRLQSINPDFISVTLGAGGTAHCDGTV
EIANLIQNKLDIPAVAHVPGLYQTQEQVLALLDRLDSINVKNILALRGDKIPGKEPVGVF
NHANELVKFVHENRPDFSIASACYPNCHTEAPDFVDDITHLKEKVDAGADHLISQLFFDN
QAFYDFKEKTEIAGIHVPIEAGIMPCTNKNQIERITQISGVPIPKKFAAIMDRYQNSKEA
MLDAGIAFAVDQIIDLVSQGVDGIHLYTMNKSKIAKRIWDETQSVFEASNLSKQTENA
>A0A432QSP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocapsa sp|TrEMBL
MNLNNTTVFRDSLLRKNEFTITYELVPGRGSGGKRLAKILRFAELAKTDGRIKSLSITDN
PGGHPALSPTSLGLEIQAMGIEPLLHFSLKDKNRNLVESQLFECHRHSLLNLLVLGGDFP
RYGFQGQAMPVFDLDSAQVLSLIRQLQQGLALKKGAPGNQMALPAMDFFTGCVVSPFKVL
ESEQVWQYSKLLTKIANGAQFVISQLGFDMHKYLELKRFIQDQQLDIPLIANVFVPNLTV
AGIMNRGLVPGVILPDSLLQIMAKEVQSQDKGEKSRLVRAAKMIAVLRDNGYAGVHIGGN
NLSFESVAFILDQAEQLNGATLEEEVHFPERHSWYFYENCNTERVERKSSLLFRLNHTVH
KLFFDRHGLLFPLTKAISLYCQRNRILNKLYTILEHICKKLLFRCRMCGDCTLSEANFLC
PQSGCPKRMTNGPCGGSIKGFCEV
>N9D8M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter bereziniae LMG 1003 = CIP 70.12|TrEMBL
MSKLSQYFAQNQFCCLVEYLPTKKQVLPVRESLAGFPACMTLSDRVRTDEDIAPLIAAQA
YPDHIEKVLHYAGKGRDIDDFKLFLKQADSVGLRDILLLTGDKLKKHHDGQGQHARTRYL
ESVNAVMAAHQYGGFHIGVAFNPFKYTPAEQQAQYLKLHKKLNAGADYIITQLGFDLSAL
KQLQTFLAQEKYIQKTLACVMPLTLARAQFMVKHKVAGIVITPHMLEVLAQDQVNQCPEN
VYKRCALQILICQHLGYAGVHLSACHKADEQMLLEQYIEQYRDLNLSQCEILWNQLWQLA
EGEQLRPKVAAKRIKSALNNKVKYQFLDLIHRAMFQSSFMKGVGTFIFNASFWNRKTAAK
VLLQTEYLSKHYLLGCESCGQCRLAETLYICPETCPKGLANGPCGGTDLDRCEFGDRECI
HSVKSRLAHDVDQIQLLKEQLIPTVPIEVRGTSSWKNWYKAE
>U1SL50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. oral taxon 172 str. F0311|TrEMBL
MPFSDDDYACPCTHDHEPTLLSFEVMPPRKPSLEAPFWDTVDRLLQVRPDFMSVTYGAGG
KDRHNARSTVQRLVRDTPIQPIAHLTCVGNSTSEVVSTVYDYLDSGVRTFLALRGDPPVG
QEDWTPGPGGVASATELIHLIRTVEKRRCDAHPGEALRSAFKPLTIAVAAFPAGNPAAGT
TQQQEVERLLVKQAAGASFAITQLFWEADVYASFVELARRAGVTIPIVPGLLPATDPARL
RRVQDLTGIEVPEYLLTTLADYPHQDARDEFGAVFGSRLVHSVLDAGAPGVHLYTFNKAK
PVLDILALMGVTPDPQWSPTSHPFTRN
>A0A174H741|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium disporicum|TrEMBL
MNIREIFDQKKLVFSFEVFPPKSTSPIKNIYKALNELVKLEPDFISVTYGAGGSTINNKT
TEISSLIKNIYGIESLAHLTCISSTREQIVDITERLKLEEVENILALRGDDNGTSCGDFN
YANELISYIKEKESFNIIAACYPEGHIANKDIKLEIDNIERKIESGATSFISQLFLDNNI
YYKFLEEIEKRNIKTKIQAGIMPVINAKQMRRITELCGATIPLKFKKIMERYENNPEALT
QAGIAYATDQIIDLSSSNVDGVHLYTMNNPYVAKNISKNIGKIISSINEVQNV
>A0A2E3ATG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium|TrEMBL
MSPLSSPRQAGVPSVSFEFFPPKSEAMATRLWETVERLEPMAPNFVSVTYGAGGSTRERT
HDTVRRIAQQTHLRPAGHLTCVGATKDEVLSVAEDYLQAGVKHIVALRGDPPTGMGEVFE
QHPGGFRDSIDLIEGIREHRPELGRCFEISVSCYPELHPESRGWDAEIAFLKAKQDAGAD
RAITQFFFEPEIYLNFLEKARAGGVTMPIVPGIMLQPNFNGLKRISTLCGASLPNWLHEL
YEGLDEDNETRELVTANVAADLCRKLSDEGVSDFHFYTLNRAGLALSTCRLLGLKPNPAE
AA
>A0A0H3ENQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O83:H1 (strain NRG 857C / AIEC)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0K2VS85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium plurifarium|TrEMBL
MTALQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPIHLGKKIAAGAQFAQTQYCFDVPMFKAFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAQRLDRILHDEITETQVDMVK
TAH
>D5VFP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter segnis (strain ATCC 21756 / DSM 7131 / JCM 7823 / NBRC 15250 / LMG 17158 / TK0059)|TrEMBL
MTLPPTRRVIGPVARAGERSQNQNGGRPRVSFEFFPPKTPQMEESLWQAITRLAPLDPAF
VSVTYGAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRAEVDEVIRDYWDIGVRHIV
SLRGDPPPGEGGIGGVYVPREDGYANATELTKAVRAIGPFEVLVGVYPEKHPESPSLEHD
IDVLKQKVDAGATLGISQFFFDLDAFLRYVDKVRAAGITIPIVPGIMPVTNFTGLKKMAA
ACQTTIPGWLANLFDGLENDAETRRLIACSVATEMCAKLQEQGFEDFHFYTLNRADLVYA
ICRVLGLREVSPAASEVAA
>M6R4E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Icterohaemorrhagiae str. Verdun HP|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFL
>A0A7L7WMD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. 28M-43|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALSA
RGTTEIAPHLSCIGDDKSEIAELLEYYKTLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
YIREHSGDHFHIEVASYPEMHPQARSFEFDIDNLVNKYQAGANASITQFFYNADSYLYLR
DKLEKRGIDTVAQPLVAGIMPITNSSNLLRFADSCGADIPRYVRKQLTDFGDDSKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLTA
>A0A8H6UTV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus felis|TrEMBL
MEKITDKIAALPPDENYFSLEFFPPKTQMGFSNLQARLERMSQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALIDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNRDFTFAVDLVRYIRQKYGDYFCLGVAAYPEGHPVDSYQDVQDPVRDLPYL
VEKTLAGADFIMTQLTYDIEAYTKFEKMLRDHESGAFKTIPIIPGLMPIHSYKILTRTTK
LSHVQIPPQIMSKLEAVKHDDDAVKRIGVDVLTDLVEAIRKIPCPGFRGFHFYTLNLEKT
VSFIIERCGLIPDDPEDFDAIADDDYTTAPTGAQNRSLFRRRASSVNSLPHNRVIVDRLQ
VPSDGSSRASTTHEAPATSAGMPAMPPDRNTTLLISEGQGALGREATWDDFPNGRWGDAR
SPAFGEIDGYGPSLHVSGTVARRIWGYPVSREDISALFRRHVSGDLYIVPWSEGGAEENS
SGLNAETEVIRPELLKLIDGKGWWTLASQPAVNGVRSDDPTFGWGPPGEGFVFQKPFVEF
FCPSKDFQTVLKPLFAKHGHEKLAWFATNAKGEFESSLPADPADADTIEMNPNNVNAVTW
GVFRGKEIVSPTIIEEVSFRAWGEEAYRIWDEWRRVYPRGTPTERFLEGVKNDVWLVCVV
GQDFGAGTEGGSEEEQQETKWMWNVLINGQ
>A0A7Y0VNX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. WS 5413|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKAEAGANSAITQYFFNADSYFY
FVERVQALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCETLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A480AVM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquabacterium pictum|TrEMBL
MAQFPISIEFFPPNTPVGSEKLKTVVQDLSILQPEFFSVTYGAGGATRDKTLATVQAIAA
LGHEAAPHLSCVGSTREGIAEILATYRAQGIRRIVALRGDLPSGTAVAGEFRYASELVRF
IRETQGPDWHIEVAAYPEYHPEQRYAAKDLQHFADKVKAGADSAITQFFFNPDAYFHFVD
AVGKLGVNVPIVPGIMPIHNFARIVQFAQRDGIEIPRWVMLKMEGYLDDTASIRAFGIDV
VAQLCQRLIDGGAPAIHFYALNQSALTLEICSRLKR
>A0A1M3E0B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. 39-10|TrEMBL
MKITDHIKNANGKTLFSFEIVPPPKGVGIADLYENIDPLMEFKPPFIDVTTSREEYVFIE
KGNGLLERKTTRMRPGTLGICAAIQHKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IMALRGDAMKGEKYFEPAKGGNHYASDLVSQIQDLGSGKYLSGEIVCEEHNSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKYFEFVSAARAMGIDVPIIPGIK
PIATKKHLQLLPQVFKIDIPEMLISEVLKCKDNRDVREVGVEWAIQQCKELLDFGVPVLH
FYSMGKSNNILKIGREVL
>A0A522PG05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidimonas sp|TrEMBL
MSSASSISLEFFPPRDIAAQEKLVRSAKQLLALHPSYVSVTFGAGGSTRSGTAATVSLMQ
NLGCEAAPHLSCIGSSRAVLTEILDAYHAAGIRRIVALRGDTPSGMGADAGELRYASELV
RFIREHSGDWFHIEVAAYPEMHPQALTAPEDLDHFATKVKAGANSAITQYFFNADAYFDF
VNRAQAKGISIPIVPGIMPITNHSQLVRFSTMCGAEIPRWIRLRLAEFGDDRASIRAFGV
DVITHLCQRLLDQGAPGLHFYTLNNADSVLAIHRGLS
>A0A2G2E4L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp|TrEMBL
MSKQPVISCEFFPPKTEKGAQNLLLVQERLAVLKPEFYSVTFGAGGSTQDNTLEAVIAIQ
QRAAETGIXAAPHLSCVGSSKERIRTILQTYIDNGISRVVALRGDLPSGMRDPGDFRYAN
ELVQFIRKETGDHFTIEVAAYPEVHPQAQDAGVDLENFKRKVDAGADSAITQYFFNIDSY
LYFVERCQKKGIDIPIIPGIMPINNYTQLARFSAACGAEIPRWLKKRLEEFYDDSVSMQA
FTTDYLTEFTEKLIKLDVPGLHFYSMNKTQPVLTVCERLGLVR
>A0A4R8Z9X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMS1-13-1|TrEMBL
MSACNARPAFSFEVYPPKSAAAASALMSTIDHLAAAGPEFISVTYGANGSSRNSSLDVLR
YIKDHTEADGMAHLTCVGSSHADASRLIREFLDAGIRSFLAIRGDAPQGAVEGDNTFLGD
LHSAGELVQLIHRVQTERVPYIETVIPGLPGARGVKTERSKVRIGVAAFPNGHPNSRSVS
QDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLFPILPGIMPVTSPNRLRRI
LQLSGEKLPAELCIELEVEPTEEGQRQIGIDYAVRLGQDVLAGGAPGLHLYAFNQHDTVL
QVLEGCGALPVPAAML
>A0A1X2FXN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterium sp. PSU-2|TrEMBL
MRNSENLCQKLKNKQFVITVEISTPKGADISNSIEEAKKLYGIADALNITDCPMANMRMS
PIALAHLLQNHLNIETIFHLTCRDRNLIGLQAELLGAYALGVRNILALTGDDPKRGDVPQ
ATGVYDVDSVGLVKIAKSLNDGFDYSGNKLESSTNFCIGTTANPNDLRPESIEKLRTKIE
CGASFIQTQPVYDDEILYRFLDAVEQFDIPVLVGVLPLKSYKMAVNLNEKVPGIEIPEKI
IDRLKNGEKGEGTKIAIEFINKIKNKVGGVHIMPLGKTDIVVDIVNGVKNMRQNDIEEVL
>A0A379ARC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Avibacterium avium|TrEMBL
MSYAKEIDTLNNHLSGINGDINVSFEFFPPKNENMEKILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKHIKQETGLEAAPHLTGIDATPEELKKIAQDYWDSGIRRIVALRGDEP
AGYDKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPAWMAKMYEGL
ENDQTTRNLVAASIAMDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGVRPE
>A0A519LCQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp|TrEMBL
MSTPVSLAEARALLLSPLGPVARAGRDASRPRVSFEFFPPKSDQAEDSLWRAIQRLAPLN
PDFVSVTYGAGGSTRERTHRTVERILNETDLRPAAHLTCVDASRAEVDAVIEGYKAAGVK
HIVALRGDPPGGAGIGGVYQPRADGYANATELTAAISRIGGFDITVGAYPEKHPESPSID
HDIDVLKAKVDAGATRAVSQFFFDMDAFLRFRDRVRAAGVTLPLIPGIMPVSNFAGLTRM
CGACGTTLPDWLAAHFDGLDDDPETRKLIAASVAAETCARLQEEGFSDFHFYTLNRADLV
YAICRVLGVREDRSSALGEE
>A0A2K8QT50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya fangzhongdai|TrEMBL
MSFFHANHQEALNQNLAELQGRINVSFEFFPPRTSEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELKAIAQDYWQSGIRHIVALRGD
LPPDSGKPEMYASDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRSELSYAICHTLGVRPVTAA
>A7GDU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKNIIGE
YNYAFELIEKIKANNNFGVSGACYPEGHIECESLKQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQQKNINVPIQAGIMPVVNKKQIERIVKISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKIIESTKSIFNSINKDVAV
>A0A6N8T387|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. 4701|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATRTICERLGA
>A0A365U4C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosalinus halophilus|TrEMBL
MTDVPAVSFEFFPPKSLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRELTRDAVGTLH
KHSGLNVAAHLTCVNASRAETMEIAEGFAEAGVREIVALRGDPPKGEGSFTPHPEGFGNS
AELVEALAETGKFTIRVGAYPDPHPDAAHENADVEWLKRKIDAGAHEAITQFFFEPETFF
RFRDRCEKAGIDVPIVPGIMPIENWAGIKRFAKMCGAVIPDWLDRAFEKAERDGRTDLLA
TAQCTELCTKLIEGGVDKLHFYTLNKPELTRDVCFALGVKPEMKLEHVA
>A0A7Y1Y4Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansiaceae bacterium|TrEMBL
MHISEILQQRQPSLSFEFFPPKTPKAAGKLFETIRELERCRPSFVSVTYGAGGSTRELTH
QLVLKILEETAIPPVPHFTCVCHGREEIEDILENYARAGVRTILALRGDPPRDRLDYDRA
GDAFQFAGELVAFIREFNESGRHPGGGFGIGVAGFPEGHPETQNRVLEMDYLKAKVDAGA
DYICTQLFFDNHDFLDFRDRCELAGITVPIIAGIMPITTPGGMTRMAELAAGAHFPAKLL
KLVTPLENDLPAFAAAGVDYATEQCAELVDHGVAGLHFYTLNKSDATLEIAQRIGLA
>A0A6L6YEP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella sp. 10-1|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A074YQM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium subglaciale (strain EXF-2481)|TrEMBL
MHISAKLQAAAKEKKSTYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDEALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDDPEELITHLKEKVDLGGTF
IVTQMFYDADIFLAWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDSAVRDVGTGLVVELCRKLLDNGILHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFRDVATLFANYMQGKVESLPWSESPITDEADALRLDLID
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVINDLMQNWYLVNIVNNDFREQRGIFPLFDKLEVPDIDKEITAPEVSQ
ETNGVTNGEKHDEEKKEEAKTGNGEVTDTKIPDSINGAEEKADTEPKDAPAHNTGAGPST
SI
>A0A1G8Z539|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora mzabensis|TrEMBL
MTTNAQQQLQRYLRNARYEVLPLRGVVEQVRELPAGTTVTVTSSPAKGTEATLDTAARLH
HEGMHVIPHLAARLVRDSAHLSDLLARVSDLGLTEVFVIAGDAERPAGRFTDALSLLRGM
EEIGTRPHRLGITGYPEQHAFIPDRMTIQATDEKARYADYIVSQICYDPNTIASWVKSMR
ARGVELPVYIGAPGSIDPSKLLRISMKIGLGQSMRFLRKQHGVVTKLLTRYTPENVFDEL
SPYLVDPAYNIAGWHLFTFNEIGKTRQWAIEMADRLQEVPA
>A0A373K2T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF46-9NS|TrEMBL
MKIRDILNKDTATISFEVFPPKKSTDFGNVEVAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAGEIQKQHNVPTVAHLTCVCADRSSIGAALTEMQAVGIENILALRGDIPKDFDGEVFT
DFTHASDLVRFIKENGDFCVGGACYPEVHPDSANKNADIQGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIIPGIMPITRGVQVKNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNLSEILKA
>D1P7P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia rustigianii DSM 4541|TrEMBL
MARSQGMSFFHANQREALNQNLAELDGQINVSFEFFPPRSAEMEQTLWKSIDRLKNLKPK
FVSVTYGANSGERDRTHSIIKDIKDKTGLVAAPHLTCIDANPEELKSIARDYWNNGIRHI
VALRGDLPDNSNKPEMYATNLVELLKNEADFDISVAAYPEVHPEAKSAQADLINLKKKIE
AGANRAITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFRQLERFAKLTNVRIPTW
MSKMYEGLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A1G7ATG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. CF079|TrEMBL
MPFVRTANQEPAVRLPLSFEFFPPKTPEGAAKLRTVRQQLYVRQPEFCSVTYGAGGSTHE
GTFGTVREILGEGVDAACHFSCIGATRSTVREQLAELKAMGVKRLVALRGDLPSGYGMGG
EFHYASDLVAFIREETGRDFHIEVACYPEVHPQARSPEADLQAFAAKMHAGADSAITQYF
FSPEAYFRFVDEARKLGLAAPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDD
MASIKAFGLDVVTELCARLASGGAPAMHFYTMNQSVATLALLERLGWDE
>A0A1F8MHC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium RBG_13_51_18|TrEMBL
MANSIFEEKLGSNDFIVTTEVGPPKSVDVSEMVHHIELLKDKVDAINITDHQSSVMRFPS
IGGCLVVKELGGEPILQMTCRDRNRLALEAELLLAYSRGITNVLCLTGDSVDVGDHKEAK
PVFDLDSVQLLKMIRTLESGTDMGGNELKAVPHFCIGATVHPEADFIEPQLIKFDKKVAA
GAQFMQTQGIFDLASLRRFMQYASQFKIKILAGIIVLSSAGMARYMNNNVPGIIVSQAII
DELAAVEKGKGLQKGIEIAARMIKTIREENLCHGVHIMAVGNEKIVPDILEAAELVNA
>A0A1B1UP98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium icense|TrEMBL
MTEVTHPAFDGHRALHSPKISFEFFPPKTEEMERSLWETINRLAPLAPNFVSVTYGAGGS
TRERTHSTIARILKETSLVPAAHLTCVGAPKGEIDDVVARYHEIGVRHIVALRGDPTTGI
GTAYHAHPDGYQSSPDLIAGIKKRYPDIEISVSAYPEKHPESPTIDADIDTLKAKVDAGA
ARAITQVFFDNDLYFRYLDRVRARGIDIPVVPGIMPMHNFKQARSFVTRAGTTVPDWLAD
KFEGLDDDAETRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A850SRU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacter latus|TrEMBL
MKTESRLEKVLASGQLAVTSEVGPPRGCNIDIVKEKANMIKDHVDGINITDNQTAMVRMS
SIAAGVALKQMGLDPIIQMVSRDRNRLAMQADILGAYALGCNTMLCLSGDHPQFGDHPMA
KPVYDIDSINMIKMVKDMRDEAKFQGGADITEPPKMFIGAAANPFADPFELRVMRLAKKV
AAGVDFIQTQCIFNTAKFEEWMKQVVDRGLDEKVAILAGITPMKSLGMAKYMKSKVPGMD
IPDEVIDRLAGVDKDKQAEEGIKMAIEQMQRLKECKGVKGFHIMAIEWEEKVPELVEGAG
LSPRPKV
>A0A7Z1RIQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hodgkinia cicadicola|TrEMBL
MINQTSVSFVAANSIYVRFSVEYFPPRKIYNLSKMLKSDLNSNQTKLLEFNSITCNSENK
NRLNPITLLLVFLRRLCNCSIILHNFFTQIKCMLISHTSMLHDLGVNNMLLISGDKYTTN
KNRNDDISPYKIRRLLREKNVFNIGTGYPDNHILCSGSFQDLFTMLLNRESGCSMHITQI
FNHMDNFLRNNLRCSIFKLGSLLPGLFISSKHPLAVDINLKCGIYLTRQVKELLESEYLD
ERAAFLFNMYRIIEIIKNDITWIQVFTLNKTRILKEIIWMLNDLTYYIRYWRLRTRNECY
AVMCDMHNAYKRR
>A0A3E2X5D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MKDIRELLQTRPLLFDGAMGTYYKAAPGVECEQANLTDPAGVLAVHREYLAAGADAVKTN
TFSLPRLAAAHAPGWEQLAQAGWQLAVQAAEEMGTAVFADLGPAPDTEAVPAGQVYTAVA
KQFAALGARNFLFETLSSDAGLLDVVGAIKAEVPDAFVLVSFAVLPDGYTREGMYCKDLA
RRMQESGIVDAVGLNCVSAPGAMRTLAKQLGGTLPLSIMPNAGYPIVTRTQVKYQGRPEY
FARELGRLAAEGTVQILGGCCGTTPAHIAALRAELDRLPVVEKTAPAEEFSTVKEQTVEN
EDAFLRKLNAGGKVIAIELDSPRNADLTGYLEGAKKLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGLCTLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPGPMTVFGALNLNARNFDVELRRAKEKLENGMSGFL
TQPVLSAQAVENLKKSRKTLGADAKILAGIMPVVSQRNAIFMENEINGIHVEDWIIEKFA
GLDRAQGEELGLAISLEMAKAALPYADGLYLMTPFNRVALMERLIGRLKQEVLGAY
>A0A8H7ZBC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces capsulatus|TrEMBL
MHIKDKLAHAEATGRPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAAIQSAFKAGCTNILALRGDPPREKEK
WEAIEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCDDQDDPDLLMQHLKEKVDAGGTF
IITQMFYDVDNFLAWVNKCRENGITVPIIPGIMPIHTYAAFIRRSNWTKIRIPPDWLEAL
EPVKNDDAAVRNLGKSLVANMCRKILAAGIYHLHFYTMNLQQATKMVLGELELIPSHKTP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGVGLKGTNEQNIKLWGEPKSLKELSEIFVRFLNGNLDRLPWSEGAVTEETDVLKLDLLD
LNRRGFLTINSQPAIDGMPSSHPVYGWGPKNGYVYQKAYLELLISPTVIDDVISRIEQNP
DLTYYCVNKKGELRTNTTDSPNAVTWGIFASKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHVASSPSRRIIQQVMDSWYLVNIVNNDFHKTHDIFNIFKDLKVENLNVQVEPIAPAAE
LVDNTRENSQDPQKQVNGSSTELTESKQEIPSN
>A0A0P6XLY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermanaerothrix daxensis|TrEMBL
MKREAFLTWLASQDRPVVADGAMGTLLNQRGVKFEECFDLLNLQKPNLVMDIHREYLDAG
AQIILTNTFGANRFKLMQHGLEDQVRVLNQMAVEVARQAVAASPNGALVAGDVGPLGVRL
APFGRVQPEQARAAFREQIEALVAKGVDLLVIETMADLYEVREAVLAAREVDPDLPVVAS
VTFTRDDRTLLGDDPVRVARSIFEMGADLIGINCSGGPNQLLRILKQMRAAVPEGRYWVK
PNAGWPERMGDRIMYPAAPDYFGDYAVAFWKAGALVVGGCCGTTPEHIAAMHRKLQDTDL
AQYENGLSITLVEREEGIAGTQQPTALAQRLAEGRFVIAAEVDPPRGLSTQKLLAGVHLL
KEAGVDVINVADSPMARMRMSPWAVCRLIQEEVGVETVLHFPTRGRNLLRVQGDLLAAHA
LGVRNVFVVMGDPTAIGDYPNAMDNYDLVPSGLIKLIKQGFNTGVDHAGMDIGQPTSFFV
GCALNLNSPDPENEIKNLRRKLRAGADFVMTQPVFDPVTARAFLDRVHEALGGLNVPVLV
GILPLVSERHAAFLHHEVPGITIPPAVRQRIAAGGEKAARVGIEIAIELALAAKSFAQGI
YLMPAFSRYDYAAEIIENVRKGG
>A0A7Z1LFY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hodgkinia cicadicola|TrEMBL
MINQTSVSFVAANSIYVRFSVEYLPPRKISNLSKMLTSNLNPNQTKLLEFNSITCNSENK
NRLNPTTLLLILLRRLCNCSIILHNFLTQIKCMLISDTSRLHDLGVNNILLISGDKYTTN
KKRSDDISPYRIRRLLREKHIFNIGSDYPNNHILYSGSFQDLFTMLLNRESGCSMHITQI
FNHMDNFLRNNLRCSIFKLGSLLPGLFISSKHPLAVDINLKYGIYLTRQVKELLESEYLN
ERTAFLFNMYRIIEIIKNDITWIQVFTLNKTRILKEIIWVLNDLTYYIRYWRLRTRNECY
AVMCDMHNAYKRR
>A0A367HW50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SDr-06|TrEMBL
MALGTASTRTDRARTVRDMLASGETTYSFEFYAPKTEKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTGTVEATQQITEDTTLTPVAHLTAVGHSVAELRHTVGQYADAGIRNILAVR
GDPKGDPMGEWVKHPQGVTYAAELVSLIRESGDFCVGVAAFPEMHPRSTDWESDIRHFVD
KCRAGADYAITQMFFEPENYSRLRDRVAAAGCETPIIPEVMPVTSVKQLERLPQLSTAAF
PEDLRDRMLAVKDDPAAVRSIGIEFATEFCSRLLADGVPGLHFITLNNSTATLEIYENLG
LHQQA
>A0A2G9FQG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hodgkinia cicadicola|TrEMBL
MINQTSVSFVSANSIYVKFSVERFPPRKISNLSKMLKSDLNTNQTKLLEFNSITCSSDNK
NRLNSITFLLVVLRRLCNCSIVLHNLLIQMRCMLISDSSMFYEFGMNNMLLISGDKYATN
KRRSDDVGPYKIRRLLRKKNVFNVGTGYPDNHILCSGSFQDLFTMLLNRESGCSMHITQI
FNHMDNFLRNNLRCSIFKLGSLLPGLFISSKHPLAVDINLKCGIYLTRPVKELLESEYLD
ERAAFLFNMYRIIEIIKNDITWIHVFTLNKTRILKEIIWMLNDLTYYIRYWRLTNRNECY
AVMSDMHNAYKRR
>A0A511DFZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sulfidoxydans NBRC 16205|TrEMBL
MTIDANDAASPLQRRVSELIAAAALEIIPLTRAEGKVLDAPRHTPLTITCSPRFGLERTA
AHVESAVGKGYRVVPHLAARMVADEGELRAFVTRMRDLGVDDLYVIGGDADEPVGTFGSA
VELLDALQGFDHGMRRIGVGCYPEGHPKIADETLIEALLAKQVHASYMVSQLCFDSEALV
RWVLETRSAGVTLPLRIGMAAPIRTTRLAELSLRIGVGQSLRFLAKQHGMVGNLLLGRTY
APEVLLRELGEQLSNPELGVEGLHIFTFNQVDVTVAWQNRFAREVC
>A0A2A4P4Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacteraceae bacterium|TrEMBL
MMSPTMDQMREAQRALDAPLFSGLPGDVEVSFEFFPPKNDKMNETLWHSVETLAPLGPRF
ASVTYGAGGSTRERTHEQVVRIQNEAHIPAAAHLTCVDATREQVDAVARHYWXEGIRHIV
ALRGDAPDGXSRYTPHPGGYANAVELIAGLKQIADFEISVAAYPEVHPDSPDAQADIANL
KAKFDAGATRAITQFFFDPQCFFXFRDKAAAAGIEGEIVPGIMPVMSFAAVQRMSGLCGT
AIPHWMEGLFEGLDDQPAARQLVSATIAAEMCRRLYAGGVRQFHFYTLNRAELSYAICHM
LGLRPKAKP
>A0A401LV13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides faecalis|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDILREFDPKYINITTHRSEYVYKDL
GNGLFQRTRLRRRPGTVAVAAAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQQQINNFNKGIFVDGSEMKVTNSPFSFGVACYP
EKHEEAPNIESDLYWLKKKVEAGAEYAVTQLFYDNKKYFKFVEQAKAAGINVPIIPGIKP
FKKLSQLSMVPKTFKVDLPEELVKETLKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A2J5HS25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus taichungensis|TrEMBL
MEKITDKIAALPPDENYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
ATRSLELAEVCQRQLQLTTCLHLTCTNTSRELVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAIDLVRYIRQQYGDYFCIGVAAYPEGHPVDSFQDTQDPERDLPYL
VEKTRAGADFIMTQLTYDVDAYVKFENRLRTHESGAFKTIPIIPGLMPIHSYKILTRVTK
LSHVHIPPPIIKKMEEVRFDDDAVKRIGVDVLTELVGGIRKIPRPAQRGFHFYTLNLEKT
VSFIIERCGLIPECADDSDALVDGGSLSALDLSAAGPNGASRSASRRRRSSLNSLPHNRV
IVDRQQFAESSRSSMTHEAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVAPAVARRIWGYPVSRDDISALFRRHVSDELYIVPWSEGGA
EEHSSGLSPETATIRPELLQLIDKKGWWTLASQPAVNGLRSDDPVFGWGPPGEGFVFQKP
FVEFFCPNKDYTTVVKPLLQKHGHEKLAWFAVNSKGDFQSSMPSQSSEADPIEINPENVN
AVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIHPRGSATERFLDETKNDVWL
VCVVGQDFGAGTKVGSKEEQEERTWMWRELIES
>A0A346E0G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Vidania fulgoroideae|TrEMBL
MKYSFEIIPFKEKKNNKKSLIMFRKFFFGLKKLSIFNPEFFSVTFSKIFNFRHTLLTCFF
VKKCGFKIIPHFPCNLSIKNINKYISILSNNRILTLFPLRGNKVNNFFKYSIKLINFIKK
KNSNFNFFSSGYPEGHPEEKKYEKDIDILKKKCRKTLGIFTQFFLGFDIYYFFIKKIIEK
KFLPKIYIGIIIINNIKYLYKMSKICSYSIPFFLKKILKKKKDXTKYLIFFIKXIKKYYK
PYCLHIYTMNKFNQSENFINQI
>A0A1H3YNH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbulbifer marinus|TrEMBL
MTDSIRISFEFFPPKTPEGREKLYKTREALQEFQPEFFSVTYGAGGTTRDTTANIVTGLR
RDGISIAPHLSFGGDNEEIILDLLNQYREAGVDRIVALRGDMPSGMGAVAQLVYANELVA
FIRRHTGDHFHLEVAAYPEIHPEAESYDDDIRFLKGKFEAGANSALTQYFYNPDAYFYFI
DQCEKAGIDAPIYPGIMPITNFANLARFSRNCGAEIPRWLRYRMESYRDPEDIKKLGLEV
VTDLCETLLEGGAPGLHFYTMNQVEPSAEVLCNLQFNQT
>A0A2M9EBG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium NML03-0222|TrEMBL
MLPISFEIYPPKNDDQRAQLGRTLEKLKAYQPQFISCTYGAGGSTREHTAETVQLLGREH
GLEGVPHLTCIGSNRQEIIQLLTHYQQQGVRRIVALRGDMPSGMLDPGELRHASDLVALV
RESFGQHFHIEVAAYPETHPQARDALADIENFKRKVDAGADSAITQYFYNADAYFRFVDD
VRARGVEVPVVPGIMPISNFSQLQRFSESCGAEIPRWVTQRMRAFGDDSGAIREFAADLV
AALCQRLMAGGAPALHFYTLNLARPVGNIFKRLQ
>A0A4Q1EUH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. CH21|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVNQVNNLGRGKYLHNEEEACDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREIGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGVEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A7V8H7Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. PEPV16|TrEMBL
MALKNEARGRNDIRVSFEFFPPKSEEMEGQLWHAVSQLQDWDPDFVSVTYGAGGTTKAPT
LSTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQ
PHPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQ
FFFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFD
DKPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGFSRRQTKNAGAA
A
>A0A358PWF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfosporosinus sp|TrEMBL
MENKFKESLLDKNTLSVTWELVPGRGANEKAQQTAIASAEQAAKGGRIHALTITDNPGGN
PAILADYLGMEILKLGIEPLVHFTCKDKNRNQMESQLYALDRANVRNLLVMTGDYTYSGF
KGRPKPVFDLDPSNTLQLITEMNKGLEVQGMKGPTYHAPSDFFAGAAVSPFKSTEAELMV
QYYKLKKKIQGGAQFIVTQLGYDARKCHEVLQFLKVNNLDVPVVGNIYVLPYGAANVMNQ
NKLPGCVVTDKLLAELNEEKTAADKGVGQRMLRAAKMYAFMKGMGFAGVHIGGHNLKYEQ
VEYIIDKGEELSANWQDYIKEFDYPQNNGFYYFEKDEKTGLNTDRPANRANRPLDAPAGF
MNSMMRGMHSLMFTPNKMLFPVMRSMYRAAEGKKKAEKRLHAVEHIAKVVMLDCKDCGDC
AILDIGYLCPMSQCPKNQRNGACGGSLDGWCEVFPKEKKCVWVRAYARLKKYGEEHTLDV
PPVPPANWDFYQTSSWSNFYLGKDHSAPILGIKRPESKIKK
>A0A349U4Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotomaculum sp|TrEMBL
MKTAELFKIKTVLSFEVFPPKKTSPLDTIYKTLNELSNLSPDFISVTYSAGGSENSESTI
AISSTIKNQYHIESVAHLTCISQTKEEVLCLLERLKDNNIENILALRGDINPDIPPKQDF
KYASDLVSFIKKNSDFNIIAACYPEGHSEAVSIAEDIRNLKIKVENGVDHLISQLFFDNN
YFYTFLERVEHAGITVPIEAGIMPVVNKKQIERMVSLCGADLPKKFTAMMNRYENNPVAM
RDAGIAYAVDQIVDLVSQGVDGIHLYTMNNAFIAQKICEAVKSLFISPL
>A0A7C6N0E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
NTIDELYGLNPDFMSVTYGAGGSTKDKTVEISSYIQNKYNLTSIAHVTCISSTKNEIDNI
LASLKDSNVHNVLALRGDFPKDADANVFPEDGFRNSVELIEYFKSNSDLCVGAACYPEKH
PDAKDLDADIDFLKRKVDVGADFLTTQMFFDNEVFYDFHEKIQKKGINVPVIAGIMPLLN
KNQIKTIKNLTGNSIPKKLRRILDKYEDNPEALKEAGMSYAISQIIDLLSWGVDGIHIYT
MNKPSTAKMILGSISAIRSVLTNESK
>A0A2N2IAR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-18|TrEMBL
MKQHILTALGERVVVADGAMGSLLFDRGVDSSSCYDALNLTDPALVRSIHKAYADAGAEI
IETNTFGANRAKLGRFDLADRTREINLRGAELARAEAGAGRWVAGAMGPLGRMGLDPFSQ
GELEDIFSQQAQALVEGGADFIILETFASLSLLLTALRGVKAGVSVPVAAQMVFTQRGRT
HSGRTARECFDALIRAGADVVGLNCGIGPKNALEVVQGLGPVTVPLSVLPNAGFPESSGD
RLIYASSPEYFARRTAACATYGARLLGGCCGTAPEHIAALVRVLDAGSPEARIISVSPDE
TRTQTAAPTRLSRRLGEGKVILVELDPPKHLDVEPVLAAAEALATAGVDAITIAENPLAV
PRLSNIVLAGMVRARTGVDVVVHMTGRDRNLVGMQSTIMGLAASNLHNVLAVTGDPPSAG
SAERVSGVYDLRSLELMALLAGFNEGRNHYGDSMRLPVNFCIGGAFNPNTRSMALQVGRM
EKKMAAGASYFLTQPVYSKERVDEILAATAHITAPIVLGIMPLASSRNAEFLHNEFPGIE
IPSETRERMARAGEHGQEEGVNIAWELLEYAWPHFAGVYIIPPFNRHAMALELMRRLGR
>A0A7Z1S252|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cyclitrophicus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLIAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRP
>A0A1J4VFP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG1_02_46_14|TrEMBL
MEIVEICKKKKWILTAELGPPKGTNLEPFLKQAGFLKGCVDAVNVTDQQAGLMKLGSLTC
CHLLRDFGIEPVMQITCRDKNRLALQSELLSASVLGIQNILVLTGDPITIGDHPLAKPVL
DLNVTELISVIKKLESGIDMTDHKLDGVPQFSIGAALNPCSDDIDTEISKTRKKIEKGAE
FFQTQGVFDPMRFKRFTDRYAEEGLKTPILAGIILLKSAKMTHFMNEKIPGIHIPQALID
RLQNAKDAKKESVTIACEIIQAIRPVVQGVHLMALGWETLIPEIVSRIS
>A0A1H0JK05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinokineospora alba|TrEMBL
MTTVLQRIRSDRPVFSVEFMPPRDQADERRLWNAIRELEGYDPAFVSVTYGAGGSSRDRT
IRTTGRVARETTLVSMAHLTAVGHSVAELRNVIGWYAALGIRNILALRGDPPGDPNGPWV
AHPDGLNYADELVALVRELGDFCVGVAAFPYGHPQSADIDADTANLLRKFRAGADFAIAQ
LFFEPEDFLRLRDRVAAKGCESLLLPGVMPLTTPKILAKTVELSGAPVPARIAARLDPLV
GDAAAFRAEGIDLVTEVCERLIAEGVPGLHFYTFNRAKATREVVGRLGLVPSRA
>A0A329HIF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. RIT 411|TrEMBL
MKPSLSFEFFPCKTEAGHEKLIATARQLASHGPEFFSCTYGAGGSTRDGTYRTVRQLNDE
VGVPTAPHLSCVGDSKAKLRELLQQYREAGINRIVALRGDLPSGMGLSGGGELRYASDLV
AFIREETGDHFHIEVAAYPETHPQARSFTDDVRNFVYKMQAGADRAVTQYFFNADCYFHF
VERVRKLGVEAPVIPGIMPITNYSKLARFSDACGAELPRWLRKQLEAYGDDTQSIQAFGE
EVMTALCERLLEGGAPGVHFYTLNQAEPCIAIWRNLGF
>A0A4Z0C7H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramlibacter henchirensis|TrEMBL
MKNKLPISLEFFPPKTEEGAVKLRAARQKLYALQPEFCSVTFGAGGSTQEGTLQAVKEIM
AEGCPAAPHLSCIGQTRESIRERLVAYAAAGVQRIVALRGDLPSGYGLGGEFRYASELVA
FIRSETGRQFQLEVAAYPEVHPQSKSPDADIAAFIAKVEAGADAGITQYFFNADAYLRYV
EELRKRGVSVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGFGDDSESIKAFGLD
VVTALCERLQAEGAPGIHFYTMNQAAATLEICRRLGR
>A0A0A1FG97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas arenae|TrEMBL
MAQKMTQKNFSIEFFPPKTPEGTEKLRVTRAKLAELHPRYFSVTFGAGGSTQKGTLDTVL
DIRSEGHEAAPHLSCLGSSRESLRAILTQYKDHGIKRLVALRGDLPSGYGAMDFSSGEFR
YANELVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDVQRYVSKVKAGANGAITQYFYNA
DAYFRFVDEAQKLGATVPVVAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTDS
IRAFGLDVVTQLCERLLAGGAPGLHFYTLNQSPATIAIWQRLKL
>A0A514C0C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. M20|TrEMBL
MSTPISLAEARALLLSPLGPVARAGQDASRPRVSFEFFPPKSDEAEANLWKAIQRLAPLN
PAFVSVTYGAGGSTRERTHRTVERILSETTLQPAAHLTCVEAGREEVDAVIEAYKASGVK
HIVALRGDPPGGNGIGGVYQPRADGYANATELTAAISRVGGFDITVGAYPEKHPESPSID
HDIDVLKAKVDAGATRAISQFFFDMDAFLRFRDRVRAAGVTIPLIPGIMPVSNFAGLQRM
GGACGTAIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFRDFHFYTLNRADLV
YAICRVLGVREQATG
>A0A1W2BK15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MTILETVRDERLTLSFEVFPPKTDAAFEEVLQATEEIAALKPSFISVTYGAGGKGGKYTM
EIARTLQNADGVETLAHLTCVGAGKEDISTYLQAMKNAGIRNIMALRGDLPEGMTPEDMK
KSPYPHASDLIREIRRSGDFCIGAACYPEVHPESTVQAEDLHYLKEKVDAGADFLTTQMF
FDNNLLYNFLYKLRETGVTVPVVPGIMPITKANQVKRALKLSGSFMPRRFTSLVDKFGSS
PDAMKRAGIIYACDQIIDLYANGIRHVHVYTMNKPDVAAAIQNHLSGMLGRAF
>A0A2S5ACZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium alvei|TrEMBL
MKVTQHIENAKGKPLFSFEIVPPQKGTNINDLYVNIDPLMEFKPPFIDVTTSREEYVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGVDAIPHVLCGGFTKEETEYLLVDCQYLGIDNL
VALRGDPMKGEKYFEPTKGGNAYAVDLVKQIKAMNAGQFLHDTLPMQNAPDFCVGVAGYP
EKHIEAPSLEADLKRLKEKVDAGADYIVTQMFFDNQRYFKFVEAARAIGITVPIIPGIKP
VAVKRHLQLLPQVFWLDMPQDLIHSIEQAKDNAAVRQIGVEFAVQQSKELIEFGVPCVHY
YSMGKSDNIHQIASQVF
>A0A7C7IH57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTGEFKSLKQALQSEPFVITAEIPPPVSAGPAELEAKIDLLKGSVHAINITDNAGAMAHM
SSLAGSAIVLNKGIDPIFQITCRDRNRLAIQSNLMGASALGIRNVLVMAGDPIKKGNQPD
AKAVFDVNAKTVLNIINDMNTKGQTMGGRELATK
>A0A6N9AUB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGSPLSDSIQFALNQLIRGYSVETTPGASTKIPDYRLILPAGTTVYVTLLPGSTIDDTIS
VCIRLANEGFNPVPHYAARQISNRQKIASSLQRFCDEAGGTQVLVLAGSSRKPVGDYENS
MQLLETGLFDQMGISKIGVAGHPEGSPDISTQGLEDALKWKNQFAEQTDAEMYLVTQFCF
QAKAVVEWERQLAELGNKLPVHIGIPGVATIGTLLKHAAACGIGPSMNFLKKQARSAKKL
LQNSTPEQLLHDLAQHRSWNSDTTIEKVHVYPLGGLRKSAEWLEHFQSEAETRSKSVA
>A0A2J8USN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pongo abelii|TrEMBL
MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKAHPECERDGGSMTLLP
DALRWSHSCPTCLLHSAASLGNPTLLRVSPTPGLQSPT
>A0A0V0W5Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella sp. T6|TrEMBL
LMASLEAVVLKATRHDLNSAAKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTTEGL
INLLKRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCILNFCLLDTMLHITSVQY
DEKTVLFNLERAKKIGIRNILALRGDISDDANVTTTDFQYACQLVRFIRSHYGDYFTICV
AEDLLNLKAKVDAGADFIITQLFFNEMHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMK
IVQLSKIVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRKLLNREHHVVPGLHFYTLNQ
EKSTRQKYTLVE
>A0A6L9SIW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytoactinopolyspora halotolerans|TrEMBL
MSQGLPTTTQGTATTIRELLSTGERSYSFEFSPPKNPQAEEQFWRTMRELERLQPTFISV
TYGAGGTTRETTVRVTGEVAMDTTLTAMGHLTAVDHSVADLRHVIGQYVDVGIRNILALR
GDPPGDPQAEWVAHPEGLHYSEQLVELIKSVGDFSVGVAAFPEGHLRSPDIDTDVRYLVR
KFDAGADFAITQMFFNVEDYLRLRDRVQAHGGNKPIIAGIMPVTNVKQIQKFAELCGASF
PEALAQRLIAAGDDREAVRAIGVEYATEMCQRLLDEDVPGLHFYTLNKSTATQEIYENLG
LGAALTPA
>A0A8I5U0B2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pongo abelii|TrEMBL
MCRGCGCLPPDAPCPTPCSRNPAMVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGL
DPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHP
AGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALR
GDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEK
VSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVP
QEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLG
MWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAF
GELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWND
EPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFT
SRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDP
VSFMFWKVKEPGASLPRPPGKPWGGIGTKSQACAEGHTGPSLQGTPGSDSPVSLLTQGVY
FWAGVGSDTGSGPCSIPGNVLLSRALGEPC
>A0A7M1U0M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus stearothermophilus|TrEMBL
MGLLDELKQRILIADGAMGTLLYSHGVDRCFEELNLSNPDEIIHIHEAYIAAGADVIQTN
TYGANYVKLARYGLQDEVPAINRAAVRLAKQAANGGAYVLGTIGGLRTLNKSVVPLDEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALSRLEALGADVVGLNCRLGPHYMIQSLEEVPLPNRAFLSAYPNASLPDYRDGRLV
YETNAEYFEEAAKAFRDQGVRLIGGCCGTTPKHIEAMAKALADRTPVTEKTVKRRTTASV
SVQADRPAPTPLPELARTRRSVIVELDPPKQLGIDKFLAGAKALHDAGIDALTLADNSLA
TPRISNAAVATIVKERLGVRPLVHIACRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDVSSFDLIRLISQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVER
MEKKIQCGAHYFLTQPVYSEEKIVQIYETTKHLATPIYIGIMPLVSARNAEFLHHEVPGI
TLSDEIRARMAACGSDPVEAAREGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRY
IHEKEAAAKERKVVHG
>A0A8F5BH94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura graeca|TrEMBL
MRRLRPDRPPTVRELLASGRSFSFEFFPPKTDQGARNLWRTVRELEPLHPAFVSVTYGAG
GGTRDKTVDIVERIATDTTLTPVAHFTAVDHSQAELRQLIGRFASVGVRNILAVRGDPPG
DPMGEWVKHPDGVEYAADLVRMIRSYGDFSVGVAAFPYKHPRSPDVESDTRHFVAKCRAG
ADYAISQMFFRAEDFFRLRDRVDAAGCDIPIIPGIMPVTQLSTIDRSEQLSGAPFPAEVR
ARFEAVGDDPEAVRRLGIEHAAELCGELLDQGVPGIHFITFNKSTATREVYGLLDGAGYG
AKGSVPPMTA
>A0A3D5W434|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSTRTDISQSLSQGASETAERLARRPKPKALLLRDTPRVSFELFPPSTPEGQTGFFDTAD
QLDVLGGTFMSVTYGASGTSQARTLNALQTLTSRCTTPMAGHLTCVGAAKEAVMAVVEAY
STAGVGQVIALRGDPPRGRSTFQPHPRGFSSASELVSAISHRGGFDIGVAAYPEVHPEAH
SGKDDLDNLKRKIDAGARYAITQFFFEADTFLRFRDRAVAAGIHAPIIPGILPVVNLKRT
ITMARTCGTHVPAWVASLFDGLDEAPRVRTLVSATIAAELCTRLRDQGVDRFHFYTLNRS
ELAWAVCRMLGLRAVERAQPCRSAAASHA
>A0A3M0Z5X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MESQRKYPRAFSFEFFPPKTEEGHRRLRETYTRLAALRPCYVSVTYGAGGTTRERTFATV
SEIRRETGLDVAPHLSCIASTREGIREILQRYMAEGIRHIVALRGDLPSGMRDPGELRHA
NELVAFIREETGDHFFIEVAAYPEFHPEAPSARRDLEHFKRKVEAGADGAITQYFYNPDA
YFRFVEAVEALGVDLPIVPGIMPITNYVQLARFSDACGAEIPRWLRWRLEDFGDDLASLR
AFGLDVTCELCRRLLEGGAPGLHFYTMNKAGPTLAIWERLGLQSQAGLRQA
>A0A2E9JH88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MDSRLFSFEFYPPRTEAGESKLDAVHERLSRLKPDFFSVTYGAGGSTKQGTQQLVLKYHQ
LGSTVAPHLSFGGTDEDELRALLEAYKQAGIDRLVTLRGDLPSGIGAAANHRYASELVAF
VREETGDHFHIDVACYPETHPDSANYATDVGFFKQKVDAGADSAITQYFYNADAYFYFVD
YCNKAGISIPIVPGIMPITNYTNLARFSMSCGAEIPQWLRNRLEGFGDDVEGLREFGIEV
VTNMCEKLLESGAPGLHFYSMNLARSVTQIWNNLALSDRP
>A0A534CU51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNAESGRTPIRVSFEFFPPADEAMGAMLWKSIERLAPLAPRFVSVTYGADGSTRERTHNV
VTRIQRETPLTGAPHLTCIGASREEILEIARGYWDEGIRHMVALRGDPPQGEGARRPNPR
GFRYASELVAALAGLAPFDISVAAYPEVHPEASSAAADLENLKRKIDAGATRAITQFFFD
TDAFLRFRDALAAAGVHAPIVPGILPITRFPQVLRFAKACGTSIPGRLHERFAGLDDDHE
TRRMIAASVAIEQVEALRRHGVSEFHFYTLNRAELTYAICHALGLRPHARSASAARQEAP
A
>A0A524AVC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKTSFEFFPPRADKGKQTLAQVRRELSTIDPEYFSVTFGAGGSTQDATLETVLDIQANDG
VPAAPHLSCIDSEKSKIIELLDQYKAADINRLVALRGDIPSGVRDIGDFHYANELVEFIK
SEYNDHFHIEVAAYPEVHPQAKNIQTDLQHFANKVKAGADAAITQYFYNADAYFRFKDEA
EKLGVNIPITPGIMPITNHTQLLRFSNMCGAEIPKWILERLKLYENDLESLTLFGTEVVS
NLCQTLKDQGVDSFHFYSMNRTEPSLSIAKSLL
>A0A3D5DG77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MFESQKKPDFSYEFFPPRRPGAKVKLERTQEKLAALKPKFFSVTFGAGGSTRELTLETVV
ATTAATGVETAPHISCIGFPLERIRAVLRDYQASGITRVVALRGDLPSGTTGVGELRHAN
ELVEFIRKETGSLFYIEVAAYPEFHPQSNTAADDLRNFKRKVEAGADSAITQYFYNPDAY
FRFVDSALNSGINIPIIPGIMPIINYTELMRFSDMCGAEIPRWIVGRLRDFGDDRASIRA
FGIDVTTELCRRLLDQGVPGLHFYTMNQYEASEAIWHNLGMGDRETGIDGGNSVDG
>A0A534D809|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPILPGHTSPGRFERVLRAGQFAVTSELAPPDSADPEDVYRRARIFDG
HVDAINATDGSGANCHMSSLAVCALLTRMGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQALPVFDLDSVSLLETARTLRDEHRFLSGRKISYAPRLLLGAAE
NPFAKPCEWRAQRLAKKVAAGAQFIQTQFCYDVPLLRAFMRQVEELGLLDKVFMLVGVGP
LRSAKAAEWIRTHVPGVHIPDAIIKRLAGASDAALEGRKLCIDLIQEIRTVKGVHGVHVM
AYRQEETVAEIIERSGVLGGRVPWYPGRDPQANTDRMAS
>A0A2E8BWE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSSEELILSQTDHSSSQPSLSFEFFPPRDEDGXAKLLQGAIXKLXTFNXDXCSVTYGAGG
STRQGTQDLVXAMLATKISAAPHLSIGGSSDAALDQLVEYYQEIGVTKILCLRGDQPSGD
ASKPAYAKDLVERLQQRFPKQFELAVAAYPEVHPDASSAEDDLAHFVAKVNAGASSAITQ
YFYNPEAYGYFLDRCAKAGVSIPITPGIMPITNINALQRFSAKAGADIPRWLAKSMSSYA
SDDKGLVDFGVEVVTKLCERLLELGAPGLHFYTLNRWGASSQLCRNLGFLER
>A0A661FID3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTKENKADLFSFEFYPPKTLEGAKNLEKVHQELAQLNPDFFSVTFGAGGSTRDNT
>A0A2E5USU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKEISDATAKRIKEDLEKSYMEVIPVPGIEDKVDPLPSEMYLAVTCSPTKGVDETLDLSE
KLIGKGFKVTPHIASKCVSGEKHLETIIKKLDELGIESIFVPGGDRPEPMGDFQNALDLL
KALKKLGHNLXKIGMAAHPEGHPDVSDEVLMEALDEKKDLADFIVTQMCFDAEILNDWMT
EIHKKGIQLPVWVGLPGVIERGRLLKTSLRIGVGDSLRFLRXKSQVATELMKSSIYNPND
LLRDITEQNDINTSNLAGYHIYCFNQIETTEKWRTDIISSLN
>A0A354VYT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MALTQPKPATCLPPLSFEFFPPRDEESIDRLVSGTACRLGAYAPEFFSITYGADGSSKEG
TLRSVAALLEANRNTAPHLSQGSDTDTAIIELINRYLALGVTRLVALKGDARKAGDRRPV
YARDLVRTIRQHFGDALRISVAAYPEVHPDTASLDLEMKFFVEKVNAGADEAITQYFYNP
EAYANFLDHCARMGLDLPIVPGIMPITNYQGLMRFSERAGADIPRWLDRTLRDKSDNVAD
LCAFGDEVVTNLCERVIQMGAPRLHFYSLNRWGACSRICDNLGYVKT
>A0A534BHM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MIFEDEPVPGYPLPILPGHTSPGRFERVLRAGQFAVTSELAPPDSADPEDVYRRARIFDG
HVDAINATDGSGANCHMSSLAVCALLTRMGYAPVMQISCRDKNRIAIQGDILGGAAMGVC
NLLCLTGDGVQAGDHPQALPVFDLDSLSLLETARTLRDEHRFLSGRRITC
>A0A2E4SSL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MLEFSLEYFPPSDDTGLSSLXEQAKXMSAFNPLYMSVTHSAKDLPVNKTLNTVEFLXGKI
PTRITPXLTCAPYSISEIMSSAREYQSIGIDSVVALRGHLNGDQDHRDPFFNYSPDFIQA
LNDEFXFNISISGYPEGHPEKIDDYLDFEYLKKKXDAGANEILTQWFFSNDYFYQYRDQC
DEKGISIPVVPGILPISDIEKVKHFANVCGSRIPSXILEKFERIKGDHSDQESLGIEIAI
SQIEDLHKNGIDNFHLYTLNRSXMTESIIENFRDHLMNESKEQKKRAS
>A0A3M1KJK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MQSQLKFKRRFSFEFFPPKTEEGKAKLQTVRDQLATRKPDFFSCTYGAGGSTRERTIDTV
IALHQQGISTAPHLSCIGSTREDIASLLDLYKSHGIQRIVALRGDLPSGMGAPGELRYAN
ELVAFIREHSGDHFLIEVAAYPEFHPQAPNAEADLLNFKRKVEAGASSAITQYFYNADAY
FYFVERCEKLGIDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSESIRQ
FGTEVVTRMCERLLQAGAPGLHFYTLNQAAPSLAIWDNLNLGEKVTF
>A0A8B7C5Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phoenix dactylifera|TrEMBL
MKVIDKIAGDHDGPVVFSFEFFTPKLSGKLEDRARASDAFVAKVARMAAHGAAFCDITWR
PRDADSTLALAGRMQREVGAETMMHLTCLGMPLDRIDHAISAVRAAGVQNVLALRGDPPQ
GSPDAAVSADEAAPSGPACALDLVEHIRSKHGDYFGIAVAGYPEAHPDKISDGSEVATVE
GYESDLEYLKKKVEAGADLIVTQLFFDVDIFLKFVGDCRRVGIDCPIVPGILPIATYRNF
QRMTETCKTKVPADVRAAVEAKKGDEAALAAYGVELATEMCRQILEKGMRELHFYTMNRE
EPTLAVLRNLGLVTGADKGVPKTLAEIQNGEKAESEKKPANGTP
>A0A837GPU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WM6391|TrEMBL
MRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVRE
TQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVRGDPPGDPNADWIAHP
EGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVTNFVDKCRAGADYAITQMFF
QPDSYLRLRDRVAAAGCATPVIPEVMPVTSVKMLERLPKLSNASFPAELKERILTAKDDP
AAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPRA
>A0A4R4ZGY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea terrae|TrEMBL
MGYEVVPVRNTERDVLENVPTAVPLTVTVTEAKGIDTTLDLTERLVRQGYAVAPHLPARQ
FLDKVHVADVVARLREARVRSVFVIGGDAPKPAGELENAYALLRAMEEVHHPFEEIGIGG
YPEGHSAISQQALDLSLKQKAPMATHIITQICFNAGTTASWAADLAGAGIDLPIHAGIPG
PVNRQKLMRISAGIGLGQSARFLRKQQSLLWRFLLPGGYDPTKLTRRLGVAASKTGGNLR
GLHIFTFGDLRETELWRRRLLDSVAEKDDQP
>A0A2N9WUE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snodgrassella alvi|TrEMBL
MSFTPLSFEFFPPRTEEGRRKLAITRKQLSQYQPEYFSCTYGAGGTTRAGTLQTITDILN
DGVAAAPHLACIGASREEMTGLLQTYKNMGIRHIVALRGDVPSGVGFGHQGLRYANELVG
LIRQEFGDWFHIEIAAYPEFHPQSRSAEDDINHFVRKCQAGADSAITQYFFNADSYFWFV
DEVQSRGVNIPIIPGIMPIASFSKLARFSETCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCDHLLQQGAPSLHFYTLNQAGLVSTICQRLGY
>A0A212L342|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfovibrio sp|TrEMBL
MHIGDGIRAAKKPFFSLEFFPPSDEKILPGFFETVEKLRALAPLFVSVTYGAGGGKQRNT
LAVTAELARRGLNTMAHLTCVGAEPESISAYLAELRAVGVDNVLALRGDPPVGQETDWSK
GYFRHASDLVAFARRQQPYMGIGVAAYPAPHPESNSIALDRLHTADKMRSGADFAVTQLF
FDAREYADLLEHLRGMGIHTPVIPGILPIQSFDSLRRVLSLCGANIPGKLYLDLESANAK
GGAEAVREVGLEFAVRQIRFLLENGAPGIHLYTLNKASMCLRLAEESGLLQA
>A0A3M5SU81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas avellanae|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A090DRN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. ORS 3359|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDMVIREFVDFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAS
GSAAA
>S3XEA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter ureolyticus ACS-301-V-Sch3b|TrEMBL
MFFEKLKNNESGILLYGQTPPKQNHQNLENLLELRKKRLNLLDVDGIVIYDLQDEGDRND
EKRTFEFVKTIDPYEYYKSLELKFPGIIYKSVGKYSQDEFIKSLKFDKNIANVFVGASSK
DQKIKLSLKKAYEIKKEFAKDIPLGGICIPERHEAKHNEHLKVANKTLNGCEFFITQAVY
NAINAKNFIDDYAKLNIKKVPIIFTFTPCGSLKTLEFMKWLGISIPPFLENRLKNSIDIL
QSSVSLSFEMFEFIYRYAKNKGVVVGANVESISTRKVEIEASIKLLQDIKRSIDRKV
>A0A511V476|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aneurinibacillus danicus|TrEMBL
MPKENLKTYLNNHLLIGDGAMATWLYQLGVPIGICYEELSLSDPEIIRTVHRSYYEAGAR
FIQTNTYGAHRDALARHGLQDKVERMNRAAAKVAREAVGDDAYVVGGIGSIIAGRVRDAR
QMDTYGEQYEEQASALLAGGVDAILLETFLDLDELLLALDVIRPLTKLPIIAQLATIEVG
RTRDGYTLTRAFSELKKAGADVVGLNCRMGPAEILRSIENTVVPEDTPLSVFPNAGRLAM
SDGEYSYASVPQYFGESALRFRAQGARLIGGCCGTTPEHIRMMAQVLAERDPLPRVNPVI
TVEEGERTPIRIVSPERSKGIVDTVRQRHTVIVELDPPRDLDTEKFLKGAAALKEAGADA
ITLADNSLATTRMSNMALGSIIKTKFGAEPLLHIACRDRNLIGQQSHLMGLYALGINQVL
VITGDPARFGDLPGASSVFDVSSFDLIRMIKQLNEGFTFSGKPLKQRGDFVVGAAFNPHV
RQFDAALRRLEKKVEAGADYIMTQPVYDREMIERIYEGTKHLDIPIFIGIMPLTSSRNAE
FLHNEVPGIKLSDEARARMHAHEPGEEARREGVAIARELVDMAMEYFNGIYLITPFFYYE
MTAELTRYVHDRSAAALQVQK
>A0A512JH44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium gnaphalii|TrEMBL
MPTANSHRASRDGFRPIRVSIEFFPPKSDEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVKETNLKPAAHLTCVDATKEEIDNVVRSYWDAGVRHIVALRGDPQDGVG
TTYRPHPGGYAQACDLVAGIKKVGDFKVSVSAYPEVHPEAASLEADIDALKAKVDAGADQ
AITQFFFDNEVYFRYLDKVRAAGITIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLDDDVETRRLVAAAVAAEQVVDLVDAGINDFHFYSMNRSDLVYAICHILGLRGQAPKA
ADRKAA
>A0A7H4K226|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. JS678|TrEMBL
MTKRIPISFEFFPPKTDAGAEKLRVVHQELQLLNPDFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDADIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A7H4JZB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. JS678|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFERFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQTRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFVITQLGYDIEAL
KKAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELEALQELWNSLWQVT
SGKEFTP
>A0A7U8WB42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae F62|TrEMBL
MNYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A2W7CAA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium kowhaii|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATREEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHSGGYENGAELVAGLKKISDFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEAA
GSAAA
>A0A1W2AVD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. VK13|TrEMBL
MNISEIEISVEFFPPKTPEGASKLNLVSQRLTEAIAPSFCSVTFGAGGSTQEGTIATVQQ
LLANGNDAAPHLSCVGSSKENILSLVNRYQEMGVKRIVALRGDLPSGMGQYGEFHHANEL
VSFIREKTGDWFHIEVAAYPEFHPQSSSAESDIQHFVNKVKAGANSAITQYFFNSDAYFQ
FLDDVESRGVTVDIVPGIMPITSSTQLMRFSDTCGAEIPRWLRRRLEGFGDDTASIKAFG
EEVVSDLCLQLISGGAPGLHFYSLNMAEPTIQIVNNLR
>A0A1H8AUU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium A37T11|TrEMBL
MKITEHIANAKGKTLYSFEILPPIKGQGIQAIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLVLRGDARKSDASFIPTPGGHAYASDLLQHVVNMNSGRYLHEDMENSEKTNFCIGVAGY
PEKHFESPNLDTDFGYLKKKVALGADFIVTQMFFDNSKFKAFVDKCRANGITIPIIPGLK
PLTSRKQLVGLPKIFHLDIPLALSEAVQACKTDQNVREVGIEWMIQQCKELKEMDAPVLH
FYTMGNPNPTKRIIKAVF
>A0A5B7Y793|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. 1643|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIVDLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A374IYJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. OM08-9BH|TrEMBL
MKLSEAMREKMLLSFELFPPKTEKGMANLPGTIEHLMKYKPEYISCTYGAGGGNVGANRE
VCQMIKNAGTTPVTHFTVIKNTKEGIKEQLEQYLAEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRDEFGDKFEIAVAGSPEGHIACRSLDADIAVLRQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDQAATINMALSRNGCVMDSELCRLISRNWLFPN
PFNAKDADGKPFDMFYEDKVKRFKEEGIEYTIRQIDEYRALGVDGIHLYALNKWKDVSEI
IDRSGLRTLI
>A0A391NHI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. (strain SCT)|TrEMBL
MLASRSDLQRLEDVLGAPRPTTLDSPMSTSPRPSISFEFFPTKTDAGHEKLLNVARQLAG
YQPDFFSCTYGAGGSTRDRTLNTVLQLDGEVKVPTAPHLSCVGDTKAELRELLNIYKDAG
IQRIVALRGDLPSGMGMASGELRYANELVEFIRSETGDHFHIEVAAYPEMHPQARNFEDD
LANFVRKAKAGANSAITQYFFNADCYFYFVERVRKLGVDTPIVPGIMPITNYSKLARFSD
ACGAEIPRWVRKQLEAYGDDMQSIQAFGEQVITEMCEKLLAGDAPGLHFYTLNQAEPSLA
IWNNLGLSR
>A0A5N6SLQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus pseudotamarii|TrEMBL
MLPFPLIGGSVKLRPKPFPPRLISPQSSFFNHHLSRNFAGTDSGNKMEKITDKIAALPPD
ANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGTTAQRSLELAEICQRQ
LQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNRDFT
FAVDLVRYIRQKYGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTLAGADFIMTQ
LTYDIEAYTKFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVQIPPQILSKL
EEVKHDDDSVKRIGVDIITNLVDGMRDIPCPGLRGFHFYTLNLEKTVSFILERCDLIPPY
SEDFDAIEDGGDISAMDGAQLRSLTRRRASSINSLPHNRVIVDKLQASEVSSKASVSHEA
PATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPSLH
VPPSVAHRIWGFPVSREDISALFRRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPELL
QLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKPLL
QKHGHEKLAWFAANGKGDFESSLPAQTSDADPIEMNPNNVNTVTWGVFRGKEIVTPTIIE
EVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNETKDDVWLICVVGQDFGAGTEMGSEEE
EDEKKFMWRVLVNAK
>A0A5R2NNE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2D.F.Ca.ET.145.01.1.1|TrEMBL
MNARQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GCAVNPFAPPYDFRPVHLGKKIAAGAQFAQTQYCFDVPMFKTFMQKARDLGHTEKLFLLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
IHVMAYRQEEYVAEIVDESGVLKGRQPWQREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A4T3F2C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteraurantiacibacter aquimixticola|TrEMBL
MSYAAIHPNWEKNAENMVDGYSLEMTAKEIEGLREAAPLIRPNTQVAVTFLPGEELEQRV
EAAVLVRELGFEPIVHLSARRIESEEQLDWYLGEITKKAQVKRVFIIAGDPPEPEGPYSD
SLQIIETGLLEKHGIEIVGVGGHPEGHPNNTPAELWDWMERKIAAVRAHGMTPLVVTQFA
FDDDAIVAWLAEMRERGIDVPVRLGVPGPAGIKRLLGFAKRCGVGASASVMKKYGISLTN
LIGSAGPDKLVDSLNSKLGEQHGRVRLHFYPFGALTASAEWINAYHAKHS
>A0A3E5EUC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dorea formicigenerans|TrEMBL
MTCKIRDILKDQTPQVSFEIFPPKTDAGYDSVLSAAEKIAALKPSFISVTYGAGGGTSKN
TVSIASHIKDDFGVTSLAHLTCVSSTREEVHQVIDKLKEKKIDNILALRGDIPKDNAFPL
PNQYRYACELIEDIKQQGDFCIGAACYPEGHVETEHKKDDISNLKTKVDCGVDFLTTQMF
FDNNIFYNFLYRIREKGILVPVLPGIMPITNKKQLRRSMELSGTAVPQRFLAIIDRFGDD
PEAMKQAGIAYATDQIIDLIANGINHIHVYSMNKPDVAEAIMNNLSAILKVED
>A0A2J9SFR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia enterocolitica|TrEMBL
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEETLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPHWMTSIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A8J6WY41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichocoleus sp. FACHB-262|TrEMBL
MLNSSLFPSPSCFRNALQSGEFLVTAEVAPPKGGNAAHMLQMALLLKDRVHAVNITDGSR
AVLRMSSLTASIILLQHGIEPICQVACRDRNRIGLQGDLMGAHALGVRNILALTGDPVKA
GDHPEARAVFDLEAVRLLQLISKLNQGFDANDKLMPDGPTDLLVGAAVDPQLNSWSGLQS
RFERKLVAGAQFFQSQLICDFDRLEKFMTQIAAGSNKPVLAGIFLLKSAKNAQFINRNVP
GVSIPDEIIQRLERAADPLQEGIAIAAEQVKLAKELCQGVHMMAVRREDLIPQILDLAGI
PPITQAAPAFQPARS
>A0A8C4W7J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gopherus evgoodei|TrEMBL
MVNEPHSASSGSASSRSDGSSSGSEGSKDSSRCSTPVLDAERHERLREKMRRRYDSGDKW
FSLEFFPPRTANGAVNLISRFDRMGMGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETVLHMTCCNQTKEEITGHLQKAKHLGLKNIMALRGDPIGEEWEEEVEGFNYAVDLV
KHIRCEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVSAGADFIITQLFFRSETFLAF
MKDCQAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKEVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVSGLHFYTLNREVATTEILKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIHRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELMSEESLFEVFTCYISGEPNRKGHKVTCLPWNDDPLAAETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSENITALLKVLKMKKYELRVN
YHIVNVRGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEEESPSRMIIQYIHDNYYLVNLVDNEFPLENCLWQVMEDTFELLNCPTEQ
>A0A8A5P666|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MLRSETARHNGEIRGDIRLSFEFFPPKNPEMENQLWETVAELKKWDPDFVSVTYGAGGST
KAPTLDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIG
TDYRPHPQGYENAAALVKGLRDISDFEVSVSAYPEKHPESASDAVDIDMLKRKADNGATR
ALTQFFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPSFLDERF
AGYDDDLEGRARVAAEVAAEQIADLQRRGVNEFHIYTMNRAPLVDAVLENLGLERLRRSA
A
>A0A8F9C4E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia edwinii|TrEMBL
MNPIELSFEFFPPKTQEGVEKLRATREQLLPLRPKFVSVTFGAGGSTQQGTLDTVIEMSK
GGLEAAPHLSCIGSSKDDLRRILTEYRSHGIRHIVALRGDLPSGMGSVGELRYASELVSF
IRAEFGDWFHIEVAAYPEYHPQSRTPRHDLENFARKVKAGADSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWIARRLESFGDDRESIRAFGIDV
VTGLCQRLVDAGVPGLHFYTLNAAASTKTICERLGL
>A0A538SR96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium|TrEMBL
MKNPFLKRLEEGVVLADGAMGTLLYERGIPFDRSFDLLNLQEPALVQSIHRDYIRAGAEL
IETNTFGASRIRLATHGSGDDARRVNRAGAQLARNAREEIGEVVFVAGAIGPLGKPVAPL
GTIPKEEALAAYIEQVEGLVEGGVDLLIIETQTDLEEMKLAIQAVRRVTDLPLVAEMTFT
EDGRTLYGAYPEDVVRVTQSLGVNVLGANCSVGPQRLLEIVQRLTRRTELPISVMPNAGL
PQFANGRFLYLASPDYFADYAIRLKAAGARLIGGCCGTTPAHIRRMREALARPGTGAAEA
AALDGASAPPPVPPAPQIVVEEPAAGDPASRSLLARKLANHEFVVSVEVDPPRGARPKKM
IEGAQFLKSSGVDVINVADSPMARVRMSSLALASMIYQQVGVETILHFTCRDRNLMGIQS
DLMGAHALGIRNILALTGDPPRAGDYPNATAVFDVDSVGLIRILRQLNAGTDLAGNSIGE
PTRFLIGCAVNPASEDIEAELKRFQQKMDAGAEFTMTQPLYELEPLTRFLEAFGKKRVPV
LLGLLPLQSHRHAEFLHNEVPGINIPEHAREAMRNAGEKGIEVGVEMCRALLLKAKDLVE
GAYLMPSFGRYEVVARVAEVVRTAPKRAPKAASPA
>A0A378XGQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oligella ureolytica|TrEMBL
MSMPEKSDSRFFSLEYFPPREQAGRERLVGTTKQLLEIDPAYISVTYGAGGSTRSGTTET
LLMVKELGHEAVPHIACIGSQPEEIIELLDFYKDKGVRRVVALRGDLPSGMGLSHSPLRY
AVDLVRLIKEHSGDWFDISVAAYPEMHPQAGSFNDDIDHFVEKVRAGADAAITQYFYNID
AYWDFVNRVQAKGVDIPIIAGIMPITNYTQLARFSKMCGAEIPRWIAKRLESYGDDIESI
RAFGHEVVTKMCDNLRSGGAAGIHFYSLNQAEPVLKIWRELEAK
>A0A1I0WGJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas sp. OK607|TrEMBL
MAKKNFSIEFFPPKTPEGAEKLRVTRAKLAELHPKYFSVTFGAGGSTQKGTLDTVLDIRS
EGHEAAPHLSCLGSSRESLRSILAQYKDNGIKRLVALRGDLPSGYGAMDISSGEFRYANE
LVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDVQRYVSKVKAGANGAITQYFYNADAYF
RFVEEAQKLGATIPVIAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDTDSIRAF
GLDVVTQLCERLLAGGAPGLHFYTLNQSAATIAIWQRLKL
>A0A2L2LD80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNPEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMISDSHLATAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYK
PHPEGYENAAALVKGLREIADFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A5B1AND4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MLRSETARRDGDIRLSFEFFPPKNAEMETQLWETVAELKKWDPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLSTAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYQ
PHPEGYENAAALVKGLRDIGDFEISVSAYPEKHPESASDAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>R4SMY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis keratiniphila|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTPRTLHTSIKLSGAPAPRRLLDRLEPLA
GDPKAFRAEGIDAVTELCERLIAEGVPDLHFYTFNRSKATREVVGRLGLVPARA
>C4XPB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solidesulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1)|TrEMBL
MPAMPTPLEEFLGKGGPGENPFVQKGVFPRFFLPLPKGDAVRIRELMEARRPFVSLEFFP
PKEREAWDGFFGVVEKLIPVRPLFVSVTYGAGGSTHAHTLEIVSRLKTAYGLEPMAHLTC
VGASKDKIRGFLGALAQAGVDNVLALRGDPPKGQETFVPDSEDFQHASDLVAFIRAEYPN
LCLGVAGYPECHPEAVSPQEDLEHLRHKLALGGSFAVTQLFFDNDRYFDFVARARAAGID
APMVPGVLPVLSLASIKRFAALCGASLPPAYMAELEAADAAGGNAAVAEVGIAYARKQAQ
DLLRRGAPGVHLYTLNKAEAVLSIVSGLEY
>A0A838K1H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euzebyaceae bacterium|TrEMBL
MQRTVRELLATGEPSFSFEFFPPKTDDGWNQLWRAIRELEPLQPAFVDVTYGAGGTTRDR
TVELVRRIAEETSLTVVAHLTCVSATEAEILEVIDELAAAGIRNILALRGDMPGDPSAAF
RPTAGGLDYAEDLVRLLKASGDFCVGVAAFPEKHREAPDIDTDTKFLAQKCAAGADFAVT
QLFFHVADYVALVERLRGLGCDVPVIPGVMPVTNVRQILNISRLSGAAFPPDVARRLHAV
EDNPEAVRAIGVEVAAQLCRQLLAAGAPGIHFYTLNRSTATREIYESLHADLA
>A0A1H2QKZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium KHCPX20|TrEMBL
MKITEYLKQHILITDGAMGTYYNKCYPLEGGLVEQAVLTDPKRIVRIHEEYIEAGAQLIR
TNSFAVNDLFFSDANQRNLIAKKSFRLAMEAVEASGKDVYVAADFGTLFHPVMQDLEQLL
SVVTSMVDAFYEVGARIFLFETQADTYGLDEIFTYIKEKDSENEIILTFSFDKNGYTKGG
LSFERILQQYGTDPKVDVYGVNCGMDPSHIKDLMEQTTFYSDKPWMVLPNAGYPYILRGQ
TLYRESADYFVSTMEKVLDLGANVVGGCCGSTPEYIRKMVERFGKRRPMPKDIGDIPTSM
TMEGRTLSSFWKKLGTGEKAFVVELDPPFNEDISKVVQGAKLLKEAKVDLLTLSDSPLGR
TRMDPMLLGAKIQKESGIFVMPHVACRDRNLISLRGMLLGSYVNDIRHFLMVTGDPVPAA
DRSHVTSVFDYNSIRFMNMAKMMNSDVFAKDTIVYGGALNYHGRNVEAIAKRMQLKMDQG
CSYFLTQPVYSQEDIQRVAQLKEMTGANIIAGIMPLVSYKNAIFMTNEMPGIHIPDEIVS
RYHPDMTREEAEDVAVSTSLDIARNIAGVCDGYYLMTPFNRVTLIVKIIDAIRNELA
>A0A2G2DME8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotalea sp|TrEMBL
MNRIFNDDISANDKFVVTLELVPGRESGGRTTDSIKEIANQAFKDGRISAVSITDNPGGN
PALSPDVLGRDILDRGMDVIVHFTCRDANRMGLESRALQLAHMGLRNILTLTGDFAGEGF
GGRGAAVFDFDSVVLTSMLKDLNRRLIRSGDEAVFITGCAVSPFKYTEAESWVQYKKLER
KVEEGASFTITQLGYDVDKYEELLLFMRDKDMQIPALASLYHLGKGSARVMNAGKVPGVH
VSQELLQKIAGQWDVPDVGRREAVERTARLGVVLKGIGYKGIHIGGIHGNFDAVEKILDR
MEAIEHNWEEYREEFTEDRKNRFYLYRRDFDPKRKIPATKPIEINLTESCHYLFLRTAHE
IFFDKKASLAPVYKKVSFSLDKAKRSWILKRFFEDPFKKIMLSCEGCGDCGIQHVGFLCP
ESGCPKHTRNGACGGSKDGYCEVNVDRLCVWVRAYRRMKKYGELEKLTAEFVPPRLWELK
DTSSWVNFHLDRDHQKEQK
>A0A6C7IIZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium (strain D23580)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0Q9Q097|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Soil774|TrEMBL
MSDGRGLSMRELLERGERSFSFEFFPPKDEAGEQQLWQAITELEPFGPTFVSVTYGAGGT
TRDRTVAITARIARETGLLPVAHLTCVGHTTAEISAILDDLSSAGVRHVMALRGDPPAGP
GSPWTPTEGGLTYANELVALIRGRADMRIGVAAFPEGHVDAIDLDHDARVLKAKHDAGAE
FAVTDMVLRASDYVALLERAAAVGADLPIIPGIMPILNLRSMERMVEFSRRQLPAEIVDR
LAPLADDPAGLRAEGIAIATELCEALLDAGAPGLHFYTLNRSKATREIFANLRITA
>A0A0D2JJP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dethiosulfatarculus sandiegensis|TrEMBL
MKSDSRLEKVLEAGHFAVTGELGPPRGCDIEVVHKKAGYLKGIVDAVNITDNQTAMVRMS
SWATSLIAKEMGLEPNYQMVCRDRNRLAMQSDILGAAALGINTMLCLSGDHPKFGDHPEA
HGVFDIDSVQLLSMVKKMRDEEKFLGGADLKGSPKMFIGAAANPFGDPFELRVFRLAKKV
AAGADFIQTQCIYNMDKFREYMKMAVDMGLTEKTAVLAGVTPLKSAPMARYMANKVPGMD
VPDDVVKRISGVPKENAADEGIKMLCEQIEEFKEIPGVKGVHIMAIEWEHKMPEIMERSG
LLPRPEV
>A0A1W9Q9K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangiineae bacterium NIC37A_2|TrEMBL
MRIIDLLQREKPCFSFEFFPPKDEAGVESLFGALAELAPYRPAYVSVTYGAGGSTRSVTV
DLVRRIREEIGLEAMAHLTCVGSSRDELRSVLQALAAAGIENVLSLRGDPPKGEAHFSRP
PGGFLYASELVSFIRSEGFPFCLAGACYPERHPEAASIEADIEALRKKVDAGADFLITQL
FFDNQDFYRFLDRLEKAGITVPVVAGLMPITNVAQVKRFTQMCGASIPSELLSQLETSEA
DRAKVRAIGVEHATRQAEDLIRAGAPGLHFYTLNRSLATREILDNLGVPSRRG
>S2JRI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor circinelloides f. circinelloides (strain 1006PhL)|TrEMBL
MKVIDKIHKAEQEGRPFWSFEYFPPKTSQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
DLTTEIVATAQSVYGLETMMHLTCTNMPVKQIDDALEAAKNCGCQNILALRGDPPKGQAN
WESCKEGFEHADDLVRYIREKYDDYFCIAVAGHPEGHIDNPDKEDDLMQLKKKVDAGADL
VVTQLFFDIDSFLTFYKKARAIGITVPILPGVFPIQNYTGLKRVISFNNNFVPQKIWDDL
ELIKDDDTAVKEYGINLTVEFIKKFREIGVNGFHIYTFNLERSSRIVLERLNLVAPVESI
KPLPWNPSLTSKRAKENVRPIFWKNRAKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
INLKYPVEQCLEMWGKPTSIDDIAQTFARYCKGQIAGIPWSAQQLDAETDIIRQRLAAIN
LLGYLSINSQPAVNGVKSSHSIYGWGPKNGYVFQKAYLEFFVSPEKLDELIEKVGKDPQV
TYYAVNKQGDLRTNTQSDEPNAVTWGVFPGKEIVQPTIVEAVAFMAWKDEAFELWNRWAR
IYERESESAELILDITKNWYLINIVHNDFQDENGIWRLFDLEIDGEISRKLLQSNTVAR
>H0G270|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium meliloti CCNWSX0020|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSADPQDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHERCYILVGVG
PMASAKTARWIRSNVPGIHIPDSIIKRLEGAQDQKKEGKQLCIDIMNEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLRGRKPWTREAAPTDALVAERLEHIREGKEENQQQMAEAAAH
HPH
>A0A085FY17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. LC238|TrEMBL
METPNFSIEFFPPKTGEGAEKLRVVRQKLAELQPTYFSVTFGAGGTTQQGTLQTVLEIKS
AGHEAAPHLSCVGGTRESLRAILQQFQDNGIRRVVALRGDLPSGYGGGGEFRYANELVEF
IRKETGDWFHIEVAAYPEMHPQARSPQDDLQAFARKIQAGANSAITQYFYNADAYFDFID
NARKLGVDVPVVPGIMPITNYTQLMRFSDMCGAEIPRWVRNKLASFGDDTASIKAFGLDV
VSSLCERLLAGGAPGLHFYSMNQAAATTAIWQRLVK
>A0A7V6Q1N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterales bacterium|TrEMBL
MGLKQKLESGGFAVTAEMAPPKGTDFKRFKECALAVKGMVDAVNVTDFQSAVVRASSLGA
ATILLEEGLEPVMQITGRDRNRIAIQGELLSAGALGIKNVLALTGDHPSFGDNPQAKGVF
EMDSVNILQVAEILMSGKDLAGNDLSGAPDFYLGASVTPVYDPMELQLMKMKKKIQAGAR
FFQTQAVFDIELFKKFKDAMGDIDTKILVGIIPLKSPGMANYMNKNVPGIFVPDEIIERL
RKSQDKVKEGLKIAAEFINELRRQELCDGVHIMAIGAEENVPTLLEMCDLESAA
>A0A4W6CQR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lates calcarifer|TrEMBL
MVNQVQRGDGTCQSCKSDSSGASNSGGESSKESSRCSTPVLDSDRSDRLRDKMRRRMESG
DHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAT
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFVISQLFFRADTF
LKFLDDCRQIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIQQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDA
LLKMWGEELMNEVSVFEVFTCYITAQPNRSGHKVMCLPWNDEPLASETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGRNLTNAPDLQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDKQNSHGVNCKHA
I
>A0A7G9SHE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas lutea|TrEMBL
MNRQPIEALRHHEPLFAQTRGDIAVSFEFFPPKTDKMADTLWESIQTLAPLQPRFVSVTY
GAGGSTRERTHATVERILKETPLTPAAHLTCVGASRAEVDAVAQEYWDLGVRHIVALRGD
APEAGIKYQPHPQGYRDATELVAGLKQVAPFDISVAAYPEMHPDSSSRAFDLENLKRKVD
AGADRAITQFFFSADCFFRFRDEAAAAGLDVEIVPGILPVSNVATTRRFAQACGAAIPEW
LDAMFEGLDDLPSARQLIAATVAAELCGQLYAGGVRHFHFYTLNRAELSYAICHLLGVRA
RA
>A0A2D8NQY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp|TrEMBL
MTYGPCGGVNPDGSCEAHPDPCVFLQRDLPVRWTDASTIPVPAPTAAATEVADILARRAL
VMTGFPARPMVADDVSRVAEVLAPHADAALSGDAATSRTQFPPSYRGHLMTAAGMRAWIG
VNARDRNRVALEGELAALRDAGVAGVHCVTGDHTETGDRPDAAPVFDLEATTLLPRARAH
GLLPSFAESPAAPPHQIRGLRVAEKQRAGGRLCLMQYCGGVDEVAAFIERCRGVGATAPV
LPGVPVIVDDDGAALLASFHAALLPPGYAERLRTARDMRSEGIRLAIEYGSALLEVPGVA
GVVVAGGARRGDEIAYARALATIARELGGGA
>A0A5C7IXS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acer yangbiense|TrEMBL
MKVIDKIRENNKSCSDRVVFSFEFFPPKTEDGVDNLFERMDRMVSHSPSFCDITWGAGGS
TAELTLEIANKMQNMICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQ
DKFVQTQGGFACALDLVKHIRSAYGDYFGITVAGYPEAHPDAIGPDGLATLESYQNDLLY
LKKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCK
TKIPAEVTAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALAILM
NLGLIEESKISRSLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSR
NPSYGALSDYQFMRPRARDKKLHEEWGVPLKSIDDICEKFKKYCLGKLRSSPWSELDGLQ
PETKIINEQLGKINLKGFLTINSQPAVNAERSDSLSVGWGGPGGYVYQKAYVEFFCSKEK
LNLIVDKCKALPFITYIATNKEGNWISNVNQTDVNAVTWGVFPGKEVIQPTVVDPASFMV
WKDEAFEIWSRVWAGLFPEGDPSRNLLEQVQSSYYLVSLVDNDYINGDLFAAFADL
>A0A1G6H496|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter kookii|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLADFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENFDKDIQHFVEKANAGANAALTQFFFNPDAYFYFV
DRLQKQGVNMPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVTDLGLA
>A0A0Q0U1D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium oculi|TrEMBL
MSTAHLYIGHRPGVRTDTPTVSFELYPPRNPSRGSGVWAGIGRLIDTAPDYVSVTYGAAG
KSTDTRDRSVQVLLNVLDRHRDLPAVAHLTCLGSTKEELTLLVRLLLRAGIRDFLALRGD
PPGGDPTYQPPPGGPTRAVELVRLIREIAAEELPLGVGRGYNGAGAATAAKPEDYVSIAV
AAYPATSGQARANDIAALAEKEQAGADYAITQVFYSPEEYASMVRELSMVGSRLPIVPGI
MPLHDLKRLRTMEKLAGIPVPKRIERIFSQATSPERLVRDTLSATVDLIGGVLDVGAPGI
HLYTFNRPRPTLDILEYLRASGYLGRNTGARTPSDPRVDTELVSLALRRMTPSYY
>A0A1V6PFG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium decumbens|TrEMBL
MHIREKLAQREASGEPGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHS
DLTLEMVGVAQSVYGLETCMHLTCTDMPLEKVDHALQTAYKAGCTNILALRGDPPRDKEA
WEADENGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGGSF
VVTQMFYDTGNFIEWVKKCRAKGINVPIIPGIMPIQTYASFIRRSNWTKTRVPPEWMEAL
EPVKNDDSAVRDIGKRLIAEMCRKLLAFGINHLHFYTMNLAQATTLVLEELGLLPSPESP
IQRSLPWRPSLALGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGQPKSIKDLSEIFINFLSGKLDRLPWSDSPITAEANAIKDHLIN
LTRRGFLTINSQPAINGIKSSDPVYGWGPKNGFVYQKAYLELLVPSSLIDELIARIEKNE
DLTYHAVQKSGELRTNTNDSPNALTWGIFAGREIIQPTIVETISFLAWKDEAYRLGEDWS
KCHEAGSATRKLIEHVMDDWYLVNIVDNDFHRTNAVFDLFKDLEVKDFTVELPGKPETEA
SEQNGAAEQNGAATKN
>A0A0R3F777|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides sp. H092|TrEMBL
MTTNPLDHDASVAELQDPGSIADRLAGVQPGDVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDLE
RDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEEQLLRAAGDGPEEDRDEVRKVGVEVATSMAARLVAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A430FI45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium callimiconis|TrEMBL
MHKPIFSLEVFPPKRNAPVGTIYDTLDGLEGLDPDFISVTYGHGTQSDRTATARIAHTIR
SEYGIPTVAHLTALYSDHEVVDRALDMFDEAGVTAVLALRGDELPDHESVGVFPHASDLV
AYIRERRPSLKIFGACYPEGHYQAESLDKDIENLKIKVDAGATHLISQLFYDNEDFYRFL
DKARAAGIDVPIEAGIMPVRGAKSVRRMAERNASRIPKPLEAILDRWEGNRDALHAAGIA
YASQQINDLVANGVDGIHLYSMNHPGTTRRIWNNVKPLFQKI
>A0A0C1D707|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia vulneris|TrEMBL
MQSLRLHSRQRVPFSVEFNPPRDAAGEARLWRTVREFERMHPAFVSMTYGAGGSTKDRTA
RITGALAQETTLLPVAHLTAVGHSIAELRALVGSYADYGIRNILVLRGDPPGDPLGDWHK
HPDGVEYAEELVRIVRDLGDFNVGVASFPQMHHRSPDLDTDTAFLAAKLRAGADYSITQM
FFEVDHYLRLRDRLAAADPEQGAKPIIPELMPVTSLRTVARAEELSGRALPAPIMARLLR
AAGTGPEENRAAVREVGIELATELAQRLIDEGAPCLHFITLNFAKATTEVLTNLGYAVTA
APLSA
>A0A1Y2MKI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia autotrophica|TrEMBL
MSLTVSEFRAMVSGRVLVCDGAMGTMLHAAGNALDQSLPALSCSDPDLVRAVHARYVDAG
VDIVQSNTFGANRLRLHEFGLADRLGEINRDAVRIAREAAGARPGVLVAGSVSPAVSVQQ
RRRVSASARTDAVTEQLGLLDGAGVDLIVLETFGHLDELLEAARIAVEETDLPVIAQATF
GPDGRTLSGHPARDVAHALGEIEVAAIGTNCTLGPRHMLDVVRELCEHTDLPVTGQPNAG
LPRRTGPARFEYDIDAEYLVRYVGQLVEVGARVVGGCCGTTPTQLAGVVELVRERQARRR
TTVTGTVPAAPAPAPAVRDPGHSDLLAVELTPDDRGGTEQAVDAARRLHEHGVNLISVGA
GGGVRARLSPVDLALHLHQRLGVDTVATVSTWDRTIMALQADLLGAHALGMHRIVCETGN
PPLVGDYPHVDGIWDVDSIGLIELLTGLNDGTDFYGLPLPTRTTFEIGARINPGGRDLAA
AAARARDKIAAGAQFLITRPVYAVEDLERLLEQIGEPLPPVLVSIRPLSGFAEAEYLTHE
VPDVHVPPRVLDLLDRAGSGGQRVGLELATELAQQVRPLAGGLVVVPNGDPVDTVLAVAG
ER
>T1C8I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
PVSFEFYPPKTPEQHEQLERTVTRLRVHAPQFVSVTFGAGGSTLSYTPDTVRALREVHGL
EAVPHLSCMGGTRSEIAALLEQYRDIGCTRVVALRGDLPSGMATSGDFRYAADLVRFIRS
EHDRHFHITVAAYPETHPQAEDAHADVRHFVAKIEAGADNAITQYFFNHRCLFPLRRGCA
PRRRERAGRARHHAGFQLCATAALLRAVRRRNPALDRAPHAGLWR
>A0A1J5S459|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MNKPELSIEFFPPQTQEGVDKLRAARAQLAQLKPAFFSCTFGAGGSTRDRTLETVLEIQG
EGLSAAPHLSCIGSTRENIATLLSRYREAGIRRIVALRGDLPSGMAEAGEFRYASELVEF
IRRETGDWFHIGVAAYPEVHPQARSAGDDLINFKRKIDAGADSAITQYFFNADAYFRFVD
EARAAGVAAPIVPGIMPIASYAKLARFSDACGAEIPRWIRKRLEAYGDDAASIRGFGLDV
VSGLCARLLGGGAPGLHFYTLNQATLTMAIWRSLGLDRIDAG
>E6Q5B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MDIAEQLASRRPFFSFEFFPPKDDAGREALFATIASLEALGPAFVSITYGAGGSTRARTV
ELAKQIAERTGITVLAHVTAYGQSRAELRALFDELSRAGIRNVLALRGDAPRSGEANAGE
FPYASDLISYLARTYDFCIGAACYPEVHIEAAGPEDDLAHLVEKVAAGATFLITQLFFDN
DKYFSFVERARAAGIRVPILPGIMPITNYDQIARFTKMCGATFPPKLIAELEKQREHPKA
IEDLGVAYAAVQAMELLRGGAPGVHFYTLNKSPAARAIGSALLAASAWRPVFK
>A0A0N5B8E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strongyloides papillosus|TrEMBL
MAPNLDDSQNNEVKFNLDDDTLGLKRNASSVNSFFDESEVNTYTPLIKRINNQIESGVPF
FSLEFFPPKTANGVANFINRLDRFRDGGTFFLDVTWHASSDPANLDKETSSSSIARCVLD
YCRIDTMLHMTCTQYTKEQTLSHIKQCKDIGLRNILALKGDLPVDPNTSLDQKQKSKYYA
LDMIKWIKESYGDYFTIACSGYPLGHPDAESYTSDLKYLKAKVDAGADFIVTQLFFEVET
FENFVRDCREIGIKVPILPGIMPIQGYASIKRIAELSKLLIPQSILDDLEAIKHNDEAVL
KYGIDRAVKMCSQILDKKIAPSLHMYTMNREGPTREILQKLGLWKQYHIKPLPWKPHGGH
HPLRCKEDVRPIFWSARPKSYIFRTREWDDFPNGRWGHSSSPAFNDLKEYYMFYLNVSNK
DKELQMYGDKLYSIEDVQKVFINFLKQEENENGVKVTCLPWNEDEKGLSFETNLIKDQLI
WANENGFLTINSQPHVNGAPSSDPIVGWGKQGGYVYQRAYLEFFTKKENAQKLVDIIDSR
YSERINYHVIDRTGKYERFNYNGTNPIALTFGIFAGSEVAQPTVVDPLSFRVWKDEAFDV
FNIWSSIYPPESKCCETLKFLHDNYVLMTLVDNEYVKPTIIYDLLKEIV
>U4QPM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospirillum sp. Group II 'C75'|TrEMBL
MTFREALNAREFLVTAECSPPKGTRIDGLLDRLTPLKNRIHGINVTDNQTGVMRMCPMAM
GLHLKGIGLDPIIQITLRDRNRLAIQSDLLGMSSLGLSQVLCLTGDPPKLGDHPEAKPVF
DIPTQELIRAITLLNGGTDLSGKDLNGKTDILPGAACSPEGDQETEFRKFEEKFDAGARF
FQTQAVFSPEKMEEFMRFASPFSVPVIAGIILLKSAKMARYLNDHVPGITVPPPLIERLD
KCPPGQALESGIAIAAETIRAIRPLVHGVHIMTVGAEETIPRILDQAFG
>A0A0U9HN25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidanaerobacter syntrophicus|TrEMBL
MSLLQKALENNEFAVTAELAPPKGIDFSHALQCAELFGERVHGINVTDFQSAILRATSLA
MCKALIDMGLEPVFQITGRDRNRLAIQGEMLSAGFFGVENLLALTGDHPTVGDNPDAKPV
YDLDSVGILQAATLLSQGVDMGGNKLETYPSFFLGASVTPEYDPIELQLIKMQKKIQAGA
KFFQTQAIYSIETMKKFKELTKPFNTKILAGIIPLKSAGMAKYMNKNIPGINVPDELIER
MKKSSEPAKEGIKIAGELIYELRDKNLCDGVHIMAIGAEENVPLILDEARL
>A0A634WRF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSSKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A524M2D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanosarcina sp|TrEMBL
MLFNFREKLNSRKFLVTVEVSPPKGTRFSAPLEDACQLKGVADALNVTDNQCSIMHMSSL
AFSKLLLDQGHEPIMQLTCRDRNRIGLQSDLLGAYALGIRNICLMTGDHPTCGDHPGSKP
VYDLDSVQLIELVRKLDSGIDFAGKRLDGGTSFCAGAVSGIDPENTLQLIKLEKKVRSGA
DFIQTQAVYDVGMFEEFMEAVNHLEVPVIAGLIPLKSLSMAEYMNKNISGIHVPEEIMLR
MKDASSPIEEGLSIASDTIKELTKLSRGVHIMPIGSHKNTPRLLSMAGISEK
>A0A848KZE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia asplenii|TrEMBL
MVQAASEGVDVGLADRIAGREDGLLLFSITPPRRSTTPEDAQRIADVTVERLHAIDVDGL
ILYDIDDESDRNPSERPFPYLPTKDPAEFYQQHLTGWDKPVVVYRCVGKYEEGQLSDWLA
AQDPDKVLTTFVGASTGEKVRRTDLPTAQKLWHEVAPQMRLGGVAIPERHSTGGVEHSRL
VRKQQAGTSFFVTQVVYDTSAAKSMVSDYFYACEEAGLEPVPVIFTLSVVGSMKTVEFLE
WLGVEVPRWVRNDLEHSPDPLAKSYDQCILAARELTSYCEQLGIPHGFNVESVSIRKAEI
EASVRLASHLRTRRLR
>A0A0J7Z9R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces viridochromogenes|TrEMBL
MALGTASIRSDHARTVREMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVGPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPLGDWVRHPQGLAYAAELVELIKASGDFCVGVAAFPAMHPRSADPETDVRHFVD
KCRAGADYAITQMFFEPEDYLRLRDRVSAAGCDTPIIPEIMPIASVRTLERIPSLTNASF
PVALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHHPPQA
>A0A117LIS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parcubacteria bacterium 33_209|TrEMBL
MKTVELFKVKTVLSFEVFPPKKTSSLDTIYKTLNELSNLSPDYISVTYSAGGSDNGESTV
EISSTIKNQYHIESVAHLTCISQTKEEVLFLLERLRVNNIENILALRGDINPDIPPKQDF
KYASDLISFIKKNSDFNILAACYPEGHIEVASIAEDIRNLKIKVENGVDHLISQLFFDNN
YFYAFLERAEHAGITVPIEAGIMPVVNRKQIERMVSLCGVDLPKKFTAMMNRYENNSVAM
RDAGIAYAVDQIVDLVSQGVDGIHLYTMNNAYIAQKINEAVKSLFISPRW
>A0A218ZBC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marssonina coronariae|TrEMBL
MEKITDKIAALPPGSSYFSLEFFPPKTTMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRALVDQALEDAKALGIRNILALRGDPPRSEE
YREPDENGQSAQAMEEEFEWAEDLVRYIRKQYGGYFCIGVAAYPEGHADESDPNGQSLEH
DLPYLVGKVAAGADFIMTQLFFDVDAYDGFEKRLREHESGVFTDMPIIPGMMPIQSYQMI
KRTAKLSHARMPANVISRLDEVKGDDEMVKKVGVDVVSEIVAHIQKKAAPGPRGFHFYTL
NLEKAVAFILERTHLIPSLPLASESAILDVPSPLESVQLNGSSHTRPSRRHSSIGSDPHN
RVIISGPKTSNPDRETTALEAAIPAEPVNTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAYGEIDGYGVSLHMSVAQALKLWNHPLSSADITSLFIRHIEGSLPAIPWSEEGLNE
ESNTIKSQLLTLNQKGWWSVASQPAVNGVTSSDPIFGWGPKNGFVFQKAFVEIFIPSSEW
VSLRAKLASAAIAPNVSWYASNASGTFLSSSPNSSEGNSGSTNAVTWGAFPGKEIITPTI
IEEVSFRAWAEEAFGIWGEWGRVYPPRSASKKCIDEVAADVWLVNVIHHGYVEKEGLWEL
LLG
>A0A1C6HZK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Eubacterium sp|TrEMBL
MRIPELFKEGKTVLSFEIFPPKKTSSIDTIYNTLDELSDLNPAFISVTYGAGGNTADSKT
CQIASVIQDKYNITSAAHLTCVNCTKNDIDVILGQLKEKGIQNILALRGDINPDIPPKHD
FKYASELVTYIKEHGDFSVSGACYPEGHMETESIIDDIKHLKIKVDAGADHLMSQLFFDN
SHFYDFLEKARIAGIDVPIEAGIMPVINKNQIERMVSMCGASLPVKFTKMMQKYEHNPEA
LRDAGIAYAIDQIVDLISNGVDGIHLYTMNNPYVARRISESISSLL
>A0A417QCH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM07-9AC|TrEMBL
MKISDIYSEKKSLSFEIFPPKKTEDLENIDETLAVLCECDPDFISVTFGAGGSSNCNRTI
ELAKKIKNQYHVEPVVHLTCLHYDKKEIDEFARVLTEEGIQNVLALRGDRNPDIPEKEDF
KHASDLIRYLKPKEDFCLLGACYPECHPESENKIREMRHLREKVDAGAEVLLSQLFFDNE
QFFKFVEDCRIAGIQVPIIPGIMPVINARQIKRMVTMCGASFPERFQRIIHKYEDNKEAL
FDAGMSYALSQIIDLLVSDIDGIHLYTMNNPLVARRICDGIRNII
>J4KQX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beauveria bassiana (strain ARSEF 2860)|TrEMBL
MERITDKIAALPADGEYFSLEFFPPKTAMGFSNLRDRLHRMEQGLRPLFVNVTWGAGGST
ADKSLELAELCQRELGMTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRTDE
YRTTDDDESDNDGAADGQAFVWAIDLVKYIRKKHGDYFCVGVAAYPEGHADESHPLGQSL
AHDLPYLVEKVQAGADFIMTQLFFDIEAYDTFEATLRGHPSGAFQTIPILPGLMPIQSYA
MIKRTAKLSHAAMPPALLDRLNAVKGDDERVKAVGVDILSELVEQVRTVKTKTTPGRPRG
FHFYTLNLEKAVTFILERTHLIPDAPDEEEVVIVDAGPTSAPFLQVNGHAIPPPQRSHSR
SSRRHSSVGSDPHNRVIVGSGSGRRTNPEWEATGAEAAVPAAVSQLNARANTLAISEGEG
ALGREATWDDFPNGRFGDSRSPAYGEIDGYGVSLHMSVAQAVRLWGHPASSRDIDDMFVR
HVRGELSALPWSEEELLAESSTITTHLAALNRRGWWTVASQPAVNSVRSTDPTFGWGPAN
GFVFQKAFVEFFLSSADWASLKDRLQAPGVREVVCFYAGNAKGDLVSSDNSGSAAAATAA
ASTNAVTWGVFPSKEIVTPTIIEEVSFRAWCEEAFDIWDEWSRVYAKGSPSATLLSGIRD
DYWLVNVIHHDFVDQQALWDLLLA
>A0A0F0L3U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium azadirachtae|TrEMBL
MSFDVPPFAPTGAVSPRVPISFELYPPRTPAPVEALHETIQKLASVSPRFISVTYGAGGS
VGGRSLDVLRYIREQTAVEPLAHLTCVGSTYAGASRLIREFLDAGILSFLALRGDPPLGE
SEPFLGDLESSAQLVQLIDRAQAERAPYQERPIPGVPGAVQVTPRRKVNIAVAAYPNGHP
RSTYRNQDIDALLAKQAAGATLAITQLFFHPDDYFAFVERARRAGVTIPILPGIMPITSP
ARLRRVLELSGEELPAELSIALEVEPTTEGRTEIGVAQAAALVRELVDGGAPGVHLYAFN
QHRTVLDVLEEAGVLDAAPPASRHVDRRPAVPTGRR
>A0A3R8VNE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKANAGADSAITQYFFNADCY
FYFVERVRKLGVQTPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A1E4J1A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp. SCN 67-85|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAVRQQLYARKPQFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRATVREQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
REETGRDFHIEVACYPEIHPQARSPEADLQAFAAKVKAGADSAITQYFFSPEAYFRFVDD
ARKLGLDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKSFGLDVV
TDLCARLAEGGAPAMHFYTMNQSAATLALLERLD
>A0A5A7P621|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Striga asiatica|TrEMBL
MKVIDKIRESSAGNAVFSFEFFPPKTEDGVDNLFERMDRMAACGPTFCDITWGAGGTTAD
LTLEIANRMQNMVCVETMMHLTCTNMPLEKIDHALATIKSNGIQNVLALRGDPPHGQEKF
VQVDGGFGCALDLVKHIRAKYGDYFGITVAGYPEGHPDVIQDGVVPPEAYQNELAYLKQK
VDSGAEVVVTQLFYDTDIFLRFVNDCRQIGITCPIVPGIMPINNYKGFLRMIGFCKTKIP
PEIIAALEPIKDNEEAVRAYGIHLGTEMCKKILACGIRTLHLYTLNMEKSALAILMNLGL
IEESKISRPLPWRRPANVFRVKENVRPIFWANRPKSYISRTIGWDQFPTGRWGDYQNPSF
GALSDYQFIRPRARDKKIGEEWATPLKNVEDICEVIIFWSKFVFIKNLDIYKIPVLTKLS
TQQKFTKFCLGKLRSNPWSELDGLQPETKIINEQLADINLKGFLTINSQPAVNGLKSDSP
SFGWGGPGGYVYQKAYLEFFCSLESLNTLVEKCMSFPFLTYMAVNKQGNLISNMKNGDVN
AVTWGVFPAKEIIQPTVVDPASFMVWKDEAYELWSRGWGKLYPESDPSRKLLEEVQSSYY
LVSLVDNDYIHGDLFAVFQDI
>A0A5R9QGS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas nosocomialis|TrEMBL
MTSPNLPTISFEFFPTKTDAGHEKLLATARQLAEYQPDFFSCTYGAGGSTRDRTLDTVLQ
LDGEVKVPTAPHLSCVGDSKAELRALLERYKNAGIRRIVALRGDLPSGMGMSGGGELRYA
NELVEFIRAETGDHFHIEVAAYPEMHPQARNLEDDLANFVRKARAGADSAITQYFFNADS
YFYFVERVRRMGVELPIIPGIMPITNYSKLARFSDACGAELPRWMRKQLEAYGDDLQSIQ
AFGEQVITQMCERLLAGGAPGLHFYTLNQAEPSLAIRNNLGFAR
>A0A5N6LFY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mikania micrantha|TrEMBL
MKVIEKILESTAAGDAGKTVFSFEFFPPKTEEGVENLFERMERMVAHNPTFCDITWGAGG
STAELTLEIARRMQNLVCVETMMHLTCTNMPVEKIDHALETIKKDGIQNVLALRGDPPRG
QDKFVQIQGGFACALDLVEHIRKSYGDYFGIAVAGYPEAHPEVIESNGLATPEAYANDLA
YLKRKVDAGADVIVTQLFYDVDNFLKFVNDCRQIGITCPIVPGIMPINNYNGFIRMTGFC
KTKIPSEITAALEPIKDNEEAVRAYGVQLGTEMCKKIMASGIKTLHLYTLNMEKSALGIL
TNLGLIEESKISRPLPWRRPTNLFRLKEDVRPIFWANRPKSYITRTTGWEQYPHGRWGNA
ANASYGALTDHQFMRPRARDKKIQEEWVVPLKKIDDISEKFMKYCLGQLKTSPWSELDAL
QPETKIIDEQLASINLKGFLTINSQPPVNGAKSELPSVGWGPAGGYVYQKAYVEFFCSGD
KLNALVEKSKAYPSLTYVAVNKDGNLVSNVGINDVNAVTWGVFPAKEIMQPTVVDPSSFL
IWKDEAFEIWSRGWAQLYPEDDSSRTLLQEVQNTYYLVSLVDNDYINSNLFTVFKDF
>A0A0N1BKR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. AAP58|TrEMBL
MAATSLAAARALLLSPLGPVARAGENPNPVRVSFEFFPPKSDEAEATLWKSIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRILTETTMKPAAHLTCVEASRDEVDQVIGEYKAIGVDH
IVALRGDPPGSAVSGGSGIGGAYQPRADGYANATELARAIQRIGGFQTSVGVYPEKHPES
PSIEHDIDVIKAKVDAGATRALSQFFFDIDAFLRFRDRVRAAGVTIPLIPGIMPVSNFAG
LQRMSASCGASVPAWLAAHFEGLDDDPETRRLVAASVAAETCARLQEEGFSDFHFYTLNR
ADLVYAICRILGVREQRAAA
>U2XXJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Micropelagos thuwalensis|TrEMBL
MTSMSFEFFPPKSAETEAKLWDVVNELSVIGPDFVSITYGAGGSTRDRTHKCVKHIVTKT
DLKPAAHLTCVAASKSEVDEVIEDYAHAGVKHIVALRGDMPDMAAFSPHPDGYSGSVELV
ESLAKRGGFDITVSAYPEKHPESDNMQTDIDLLKAKIDAGATRAITQFVFDTEKYYRFRD
LLVDNQINIPVIPGIMPTTNFKGVLRMSEACGASVPEWMKNKFDGLDEDLESRRALAIEI
ATDQCRDLIKSGFENLHFYTLNQATVTKAVCNALSLEKVGGHS
>A0A7D8YJ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnellula cervina|TrEMBL
MHVSQMLSEAERSKQPKFSFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLA
QLTCEMVSVAQSQYGLETCMHLTCTDMGKEKVNEALKETYKAGCTNILALRGDPPRENEK
WEATEGGFQYAKDLVKHIRDTYGNHFDIGVAGYPEGCDDQDDLDLLLDHLKEKVDAGATF
IVTQMFYDVDNFLDWVRKVRAKGITIPIVPGIMPINTYASFLRRCNHMNCSIPPKWMEAL
EEVKNDDAAVRNIGTGLVAEMCSKILGSGLIHHLHFYTMNLAQATRMVLEDLKLTPSDER
PLKQALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQEWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEQNRKLWGEPTSIKDIAEIFVKYIENGVDSLPWSEAPITSEADSIKADLI
GLNKRGFLTINSQPAVDGVKSSDPVYGWGPANGYVYQKAYLELLVSPQSMDELIQRIERD
PDLTYYAVNKAGELKTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMD
WAHCYSNLSPSRNLIQNMMENWFLVNIVHNDFHQTHGLFRLFDELSVSSIDKPFEIELKN
GIETNGVNGFKPEDSENVPLTNGA
>A0A8E6WEX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Paratyphi B|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7W0ERU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLEKILSSGQFAVTAECGPPKGTSVKVIQRKGELLKFHCDALNVTDNQTAIVRMS
SLSGCVLLKQVNVEPVMQMVVRDRNRLAIQSDILGAVALGIRNVLCLSGDHQKFGNHPTA
KGVYDIDSMQLIQTLKKMRDEKKFLSGDDISGEVPLFLGAAANPFADPFEFRVTRLAKKI
KAGADFIQTQAIFDVPKFIRWMEMVRDRGLDQKVHILAGVIPVKSVGMARYMRNNVSGLS
VPKELVDRMADAKDAKEEGVKICLETIELLKEIDGIHGVHIMAVAWEDIVPEIVEKAGLM
PRPVI
>A0A7L0X9F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tyrannus savana|TrEMBL
MVNETQQSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FVKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGTVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGHRVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7C0V6Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MLRVFQHDLRDPAHFVITLELVPGRESTGRKIDTVMGIARDAMADGRVSAVSITDNPGGN
PSLSPDVIGNEIFKIGLDVIVHFTCRDMNRVGMESRALQLAMMGMKNILALTGDYTGAGF
GGQGAPVFDLDAVSLLAMLAMLSERIEAAGDPDGFFAGCAVSPFKLTPGETMAQYAKLCR
KEAAGAKFVITQLGYDAGRFAHLLDVTRSMGFDLPVLGSVYLLTPKAARIMNAGRVPGVV
VSDQLRERVLAEWRDRETGRQAAVERAARLAAVLKGLGYKGIHLGGIHRDFSVVARILDR
LERIEDRWTEFLADFGMAAAQEPAAPAAGGEVCAMVDGPAPALGPLEKLHFNLMRQAHGM
FFARGSASAGLWRTLARRLDSHRAGRLIASTLEDPVKRLLLGCRHCGDCGIVHLAFLCPE
SQCPKHTRNGACGGSRNGRCEVHPERYCVWYRAWRRWAAAGESRRLAEGCVPPRRWELNE
TSSWLNFHLGRDHQGSGDAFARFCRSRSCRTEALANAADQIRQ
>A0A241WF99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4654|TrEMBL
MSQLSTYFTQNQFCVLVEYLCSMKEILPVKTQFADFPALMTLADRVHADDDLAPIIAAQA
YPKHIEKVLHFAGKGRDIRDFEQFLNAAQAIGQQNLLLLTGDKLKNHHKGKDSSERTRYL
ESVNAVMAAKQHGDFCVGVAFNPFKYAEAERDAQYLKLHKKLKAGADYIITQLGYDLSAL
KEAKVFLTQHGYAQKILACVMPLTLGRANFMVKHQVAGIVITPHMLKILGEEKESGLTDR
VYLRCALQILICKQLGFAGVHLSACHKPEEQLLLESYIEAYRHLGLDELELLWNALWQVK
TGKEFYPALTYYSRPVSSMQVLKYQHLNLMHDALFESKVAKGVGHFIFQSRFWNGSLAAQ
ALLKTEFVSKHGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVDQTQILKNNLIPTVPIEVRGSSSWKNWYVNQAS
>A0A7W0IW23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MNVKTPSKLEKILRSGQLAVTSECGPPRGSDPEEVVKKAKLIGDCVDAINVTDNQTSVVR
MSSLAACIRIKLLGYEPVLQMVTRDRNRIALQSDILGAASFDIHNLLCLSGDHQSFGDNK
QGQNVHDLDSMQLVQTVRHMRDEGKFLNGDEIKRPPQMFVGAAANPFADPFEIRVPRLAK
KIACGAEFIQTQCIYNLDRFEEWMKLARDRGLHEKVFIMAGMTPLKSVGMARYMKNRVPG
MDVPDDVVKRMADTPKEKQAEEGINICIEAIERLKSVEGVSGFHIMAIEWEEKVPEIVKR
AGLYPRPKVD
>A0A7C1I0J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MRLKEALKNKRFVVTTEVQAPVEQETGGLIENLNKIRGRVDGVLVSEVEFEGVAADTITA
CEIISANRFESIYQITTRDKNRLQIQKDLLEASKAGVDNLLVFTEDYRITGDSLQEMMFF
HLDAGKISSVLEHMREGRTVEGRDLESGADFLLGSGVESAWGGKVPDLALREMEEMTRVG
AGYFLTTPVFDLDRFEKFLARTSTFGVPVIAEVIILRTAGMARFLNRHFKPGLVPDRVIR
RLAEAPDKEKASIELFGNTVKGLKDICDGIHIITIGGEEKLRYYLDAAGLR
>A0A7C5HVD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
DVLGHDIFKVGMDVIVHFTCRDLNRVGMESRALQLSMMGMKNLLALTGDYTGKGFGGQGA
PVFDLDAVNLLMMLDHLSHRFHENGDPDGFFAGCAVSPFKYTEAECFAQYAKLCRKISAG
ARFIITQLGYDARKFAELITVLKQLEVNLPVFGSIYLLTPRSARIMNKGMVPGVVVTDKL
LTRVLDEWKNPKAGRVKAIERAAKLGAILKGLGYQGMHLGGIHKTFDVAGDVMSHMKAIQ
DQWQSFLPEFEYPVTNGFYVFPDDISEKSPANSFGQQPVSIPILEKIHFRLMKSFHNRFF
SFESKQARTLEKVCGWIDHHRMAEGIVTLLENSAKKILLGCQHCGDCGIQNLAFLCPESR
CPKHTRNGACGGSSDGKCEVRTDRNCVWVRTYRRMAYSGTCQNLLSGCVPPRMWELNQTS
SWLNFHLKRDHQSVSTGLEKYCRLEDCQLSFCEHYGKPLNPKG
>A0A8F9I2G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O141:H4|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7C4LVX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MALRERLAAGEFVLLAELEPPKGVHAAPLLDHARRVKERVAAFIVPEMHQAVMRMSALGA
SVLLRQQGMEAVMQVCCRDRNRLALQGDLLAAFACGIENLLVVSGEDPSLGDHHRARAVY
DVSPLELLEAIAELERGRDMAGVDLEGAPCFFTGATTQAGSPGRSAELEAEDIAQRMRAG
ARFFVTPPVFDPELLEPVVRRLARGRETLVPTVLLLKSLGMARYIDRNLPHIRIPAETIE
RLERAPDKVRECVQITVETIRTLRGRGYPAAVIATLGWEHKLPEIVEAL
>A0A1F9KPM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYA12_FULL_58_15|TrEMBL
MPNSLFDEIAERVVVADGGIGTLLYAKGVYVNQCYDMLNLTAPDTVRDIHRDYIKAGSEL
IETNTFGANPLKLEPHGQAANTEEINKRGAELARDAVGDKGWVGGSVGPLGKRLSPIGKI
SVAEAIELFRPQIKGLVAGGVDLIVIETMGDIKELTAAVQAARLECGLPILTMATFPAEG
RTIIGYTPEEVMTAMTHLGVQSVGANCSEGPHDMLATIEQLKLANPEMPIAAMPNAGSPR
LVDDRVLYMASPDYFAEYSRRFIQAGTSLVGGCCGTTPDHIRAVCAMVRALKPAKQVVTS
VEPLEKATQLDPAPIEERSPLGAKLARQSVLGNRFVVSVEMNPPRGHDVTKALAAAETLR
FHGVDVINIPDGPRASARMSSLHLALLIEQRVGMETVLHYTCRDRNLLGMQADLLGAYAL
GLRNVLAITGDPPKLGDYPNVTAVYDVESIGLVRAMQGLNRGIDLAANPIGEPCKFLIGV
GANPGAADFDREIRRFRYKVEAGANFCMTQPVYEPALLERFLKAINDCRVPVLVGILPLA
SYRNAEFLHNEVPGMQIPEPIRKRMGKSSEKNQGGNEGIAIAQEALLATRQMVDGVYIMP
PFGRIDSALRVLEVLR
>A0A7W0EVC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKLAEAFEKKRFVVTTEIQAPMEGESHSLVESLKMIRGRVDGFSISEAEMEGVVGNSLQT
CVTLKENRFEPIFQTTTREKNRLDLQRDLLKAHDAGVENLLVFTEDYRITGDSLQEMMFF
HVDSGKLESVLGHLKTGSTVEGEELPFKADFTLGSGIESGWGKNVPDLELKEMEEMTRIG
AGYFLTTPVFDVEKFAKFMQKAQTFGVPVIAEVLILRTAGMAQFLNRHLKSGLVPDWIIK
KLAQAPDKQKASIELFSDIVSGLKDISQGVHIISIGGEDKLRHYLDAAKLV
>A0A831Y0X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLERVLTSGEFAVTGELGPPKNSDPDVVRKKARLLKGNVDAVNITDCQTAIVRMS
SIGAGLIARSEGVEPVIQMTCRDRNRIGMQSDLLAASALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQMLGMVRDIRDGKKFQCGEEIKGTAPKFFIGAAANPFAHPFEFRAVRLGKK
IANGADFVQTQIIYNVDKFTRFMEMCRDLGLDDKAYILAGITPPKSLGMARYMQKFVPGM
DVTEEVIKRMQGAKDKQREGINIAVDIINQVKEIKGVAGVHVMAIEWEEAVEEIVEKAGL
LPRPTFAEIEEETVSAVPSAETISVRGTEDTTLADAKAEAQRILAAAKQEAETIRQQAAA
GRPVTTTSQITDTVAISTDDAGEHEMNEKERQLALDSVKQGIDALKKAYGLNDDQFNALL
KFIDAEAILKKEPPASGAGRPAAPAPEAAPVQPAAPAAAPPAEDKAGDDAAAKAKAEAEA
KARAEAEAKAAAEKKAKVEAGEKAEAEAKAKAEAAAKAEAEAKAKAEAEAKAKAEAEKAA
AGKPAAQEPVQKAAKAAPAEVAAPELAAESVPFADRAAKVPATSYQVNYSGAIRETLLGN
GDNAVTVGGSEVLPFHLFEGNMPRKPLIAMEIQDIKPDNWPATLTRYYDDVMDNPVAWAR
KCVDEYNAEALNIYLIGTDPNGQNRPAADAAKDAAAVIDAVDVPIIVWGCGNNEKDTETL
REITSIIGDKKVCLAPLEDANYRAVGATAMAFQHPIVAASPIDVNLAKQLNILLENLGMP
LTSVLMDPSIGALGYGIEYTYSVMERIRLAALTQKDEKLQVPIICNLGREVWKTKEVSLP
TDELLGDQEQRGIMMEALTAACMLLAGGEVLIMRHPKAVNMTKSLIKGLMA
>A0A8F6CCR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcus sp. Mc7|TrEMBL
MKTQQKYPREFSFEFFPPKTEEAAVNLRRTLNKLAPLKPRFCSVTFGAGGSTREKTFETA
LEIQQTTGIECAPHLSCIASTRQSIREILEAYRSHGIRHIVALRGDMPSGMLSAGEFRYA
NELVEFIRAETGNHFHIEVACYPEVHPQAASAESDLKNFKRKVDAGADSAITQYFYNPEA
YFRFVDDCERLGVDIPVVPGIMPITNYSQLARFSDMCGADIPRWIRKRLEAFGDDRRAIR
AFGLEVVTELCRRLLEQGAPGLHFYTLNRAEACLDVWKALELGSA
>A0A6N7YJ80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Conexibacter sp. W3-3-2|TrEMBL
MTDPAQQLLLLVAEQLERRRVGELHPPVRVDDVHRVRDARQERLEDVARREPQALADPLH
RARRHAPIVAHRARPRAGPAVESSGRRARPRGADVGSAGAPPSGHTAHGRRETTVGPRHR
GPRQDRASLAVGPARPQDPGVSRFADALAARTLLSAELTPPLGADPTAALDVARTWAGCD
LDAAQVNDHLCARVRMSGVALAALLRGTRLETVLHVGVRHRNRIAVQADLLGAHAIGVRD
LVVVPGHDVRLGPDPHAREARDLKTSAAIALVRRLADEGRLSSGYRLAGPLRFRVGAVEA
VGRGSTDELRRRIEAKAQAGAHFLQLQGLTDDDRATAVLDALWADGVPERVALVASIVPV
RDAAHRAQLARIPGVAGVDAEGPAAAAELGRLLLTHRATSGLHLRPLLWEDAVPPLVAAV
RAR
>A0A7V0JLF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLERLLEKGEFVVTGELGPPKGTDVDVVKKKASMLKGNVDAVNITDNQTAIVRMS
SIAAAKVLIDEGLEPNMQMVARDRNRIAMMSDLFGANALGIRNMLCLSGDHQTFGNHPEA
KNVFDIDSIQMIYMVKTMRDEHKVICGDEIEGDFKMFIGAACNPFADPFRYRVHRLAKKV
EAGVDFIQTQCIYDMKRFKEFMKQVVDMGLHEKCKILAGVTPLKSVGMARYMAANVSGII
IPEEMIARLKGAGKGNVATEGIKILCEQMQELKETEGIAGIHLMAIEWEHRVPEIMEMAG
FLPRPKP
>A0A7C1DNK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MQLEEKLRTGGFVVFGEMEPPKGADFSRFLKNASLVKGRIDALVVPEMANAVMKACSLAG
CAFLQSRGFETIMQACCRDRNRLALQADILGASALGVSAVMAVPGEDIVFGDHPRAREVK
DLDIHQLLAMLQTLAQGRDLSDVELEGTPPSLLVGSVFNAGASGGALDMELEALEKKIGL
GVRFIVTSPVFDEKRLEVLLKRIDTSKVSVIPTVLLLKSAGMARYIDRNIRHISIPAETI
QAIQKAGDKAWECVRTAAGLVSSIREMGFAGVSISTVGWEGKLPWILDAVRS
>A0A2W6Y1Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera sp|TrEMBL
MTDNPTRICSVEFFPPATEEGAEKLRATRRQLRQLNPSFFSVTYGAGGTTRDRTLETVLE
MKAEGLNAAPHLSCIGSTRDNLRQTLERYKEEGIHHMVALRGDLPSGVVDPGDFRYANEL
VEFVRAETGDWFHIEVAAYPEVHPQARNAAKDLQNFVRKMKAGADSAITQYFYNTDAYFA
FVDDARAMGVEAPIYPGIMPIANFSKIARFSEACGAEIPRWMQRKFEGFGDDAASVRAYG
LDVVTTLCERLLAGGAPGLHFYTLNQAGLTSTIWQRLGL
>A0A5P8YYH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivivax sp. THAF197b|TrEMBL
MTRRPDVSFEFFPPQTLDASFRLWDTVQTLAPLGPRFVSVTYGAGGTTRELTREAVGTIH
KHSGLRTAAHLTCVNATREETLGIARGFAEVGVTDIVALRGDPPKGQDKFVATEGGFRDS
CELITALKETGDFTIRVGAYPDTHPEAPTDTADVEYLKRKFDAGADEALTQFFFEAETFF
RFRDACEKAGIDKPIVPGIFPIENWKGARRFAEKCGTKIPQWVIDAFETATRDGREDLLA
TALCTELCSNLIDGGVDKLHFYTLNRPELTRDVCFALGVTPETRLENVA
>A0A641UU95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides ovatus|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVA
>A0A556CNA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium aurantiacum|TrEMBL
MEATTTTKVLDDFSLEMTGKDVPSLQQAAHAIPQGTRVNVTFLGNENLQMRVEAAKEVLD
LGFVPVPHISARRLKSETELCEFLEALQQAGASEHVFVVGGDPATPEGPYSDSLSVIRTG
ILQSYGVTEVGIAGYPEGHPDINTEALWEHMEAKCTSLAEQGLGQVVLTQFAFDAEAVVA
WVHEVRSHGIEADLRIGTPGPAGIKRLLGYARRFGVGTSAGIAKKYGFSLTNLIGTAGPE
RFLKDMTSYESITSASSGVKAHFYTFGGLAATAEWVQDFTAQA
>A0A3N5FWW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKITDLYDQGVFVITSEVGPIKGAVSRDKAIDPSCAREAIFLQDHVHAVNVTDNQSAVMR
LGSLAASVNLKARGVEPIYQVTCRDRNRIALQSDLLTAYSLGIDNVLLLTGDHINLGDHK
EAKPVFDLDSVQLIKMATGLRNGVDIAGNSIENPPDMALGAVVNPNFEPLELQLMKMKKK
IDAGAQFFQTQAVYDVKIFERFMEKASRFGCPIQAGVVVLKSPQMAKYINTSVSGIHVPQ
SWIDEISGVEKADRKKKAIEMTGLFLNQIKSMVQGVHVMPLGWVDVVPGILEASGITVEE
SMRKSA
>A0YBJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine gamma proteobacterium HTCC2143|TrEMBL
MQFEDEPIAGENLPILPGHASPGRLERILRSGVFAVTAEIAPPDSADPHEVYERASLFDG
YVDAINATDGSGGNCHMSSVGMSALLTRRGYSMVMQISARDRNRIAMQGDVLGASAMGVS
NILCLTGDGVQSGDHPQAKPVFDMDCMTTLEMLRGMRDRGQFLSGRKISHPPPVFLGAAA
NPFAPPFDYRPLRLAKKIAAGAQFIQTQYCFDLVMFKRYMAKVRDMGLHEKVFILVGVGP
LASARSAQWIRNNVAGVHIPDSIIERLAGADDQAQEGVDICVEMIQQIREIPGVHGIHLM
AYKQEKRVAEIITRAGVLDGRRPWHPGMYDASDAEENRAGLRSQQ
>A0A317SEI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tuber magnatum|TrEMBL
MDKVVDKIAALPPGEPYHSLEFFPPKTSMGFQNLQARLERMARALRPLFVNVTWGAGGST
AAKSLQLAEICQRQLGLTTVLHLTCTNMSQAVLDETLEMAKEIGIRNILALRGDPPRSDD
YRNTPCDGTSNGGAGKEFEYAIDLVRHIRERYGAYFCIGVAAYPEGHVEGARPEKQDPLF
DLPFLVEKVKAGADFIMTQLFYDADKYLWFEKLLREEPSGVLSELPVVPGLMPIQSYSML
KRITKLSGASLPAGILRRLDDVKGDDEAVKRVGIDIVSEVIEKIKAADLSGPRGFHFYTL
NLEKAVSFIIERTDLIPPLDESALEEIEDPVVNGATLRRDRRTSSVTSDPHNRVIVDDSS
SLQSSRLANALEAGFLKPPEQSRPPEVALAISEGEGALGREATWDDYPNGRFGDARSPAF
GEIDGYGPSLHLSQAQAIKLWSSPVTKQDVSDIFVRHIEGELEAIPWSEQGLSVESGVIA
DHLAKLNRKGFWTVASQPAINGVKSADEIFGWGPKGGFVFQKAFVEFFCSPEDWGILGAK
LGGVEDISYYAANKDGDYVASVPLGDSAMHAVTWGVFPGKEIVTPTIIEEVSFKAWKEEA
FSIWKEWARVYPPRSASSKLMMEVAETYYLVNIIHHGYMDSEFLWRLLEV
>A0A1Y2Q9X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. IBVSS2|TrEMBL
MAAPLFADVAGDIDVSFEFFPPKTEKMEETLWESIETLRPLGPRFVSVTYGAGGSTRERT
HNTVARIARETAIPAAAHLTCVEATREEIDQVAREYWAAGVRHIVALRGDPPRAGEKYST
HPGGYANAADLVAGLRRLHPFEISVAAYPECHPDSPSQTADLDNLKRKIDAGATRAITQF
FFEPETFLRFRDDAAKAGIDAEIVPGIMPVMSFASVVRMSGMCGTQVPGWMERLFEGLDD
HPAARQLVAATLAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGVRPKVAALVGA
>A0A1E3A0D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eisenbergiella tayi|TrEMBL
MIKDLFAEKKQLLSFEVFPPKKEDEFANAFAVLDSLAGLQPDFISVTYGAGGSKSKKTVE
IASYIQNQLHIMALAHMTCVGSKKEDIDAVTAQLKEVHVNHVLALRGDRPSYMSDEQFDS
RHFSHAADLITYLKGETDLHIAGACYPEKHYEAADLESDLLHLKEKCDAGAEFLITQLFF
DNEAFYKFLEKSRNAGITLPVCAGIMPITSAKQLGTTVSLSGSAVPKQLADIIATYGDDP
ADMRKAGIDYAIRQILDLKAHHADGIHIYTMNKPKVAQEIVSAIQ
>A0A450WGH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kentron sp. LPFa|TrEMBL
MNPSDSNPLVFSFEFFPPKTSQGHDKLRATWRRLSQLDPDFFSVTFGAGGSTQVGTVETV
LEIHRDSGIDAAPHLSCIGSSRVKIREILAHYLSNGIRRIVALRGDFPPDMAEPGEFRHA
NELVEFIRAEVGDKLHIEVAAYPEFHPTAPSASADLENFKRKVEAGANSAITQYFYNKDA
YLRFVDNCQRIGVDIPIVPGIMPITNYVSLAGFSERCGAEIPRWLRWRLQEFGDDMKALR
AFGADVVTELCQELLSSGAPGLHFYVLNRAEPIMTIWKNLDLSNRQGPR
>A0A3A5AAA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MVSAFKKALQSGKFVITSEVAPPKGANLDKMKHHVELLRDKVDAMNITDHQSSVMRYPSL
GGALLVKEMGGEPILQMTCRDRNRLALQADLLFAFSRGIHNVLCLTGDSVILGDHKEAKE
VFDLESCQLLSTIRLMEKGKDLGGNALESPVSFCAGAIVTPEADPIEPQLIKFEKKVEAG
AEFIQTQAVYDLDNFNRFMEYAGKFPVKILAGIILLTSAPMARFMNKNVAGVNVPQPLID
EMASAPKGGALRKGIEIAGRMIRRIREERMCHGVHIMAIGKEEVVPDILEAAGIL
>A0A3A4W1I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSSQNGLKSGSNLEKVLKAGHFAFTGELGPPRGASADEVRKKAAHLKGMVDAVNITDNQT
AVVRMSSWAASLLLIQEGLEPNFQMVCRDRNRLAMQSDILGVYAHGVRNMLCLSGDHQKF
GDHPQAKGVFDIDSMQLICMVKRMRDEAKFLSGADIEVAPRLFIGAAANPFADPLDWRVH
RLAKKIDAGVDFIQTQCIYNMDRFREFIRQANDMGLTGKAHILAGVTPMKSVGMARYMKN
NVPGMDVPEALIERLQGAGKGKAAEEGIKIACEQIEEFKQMKGVAGVHLMAIEWEHRVPE
IAERAGMLPRPVVE
>A0A3A4WYX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MVTQSALEKVLAAGHLAVTAECGPPRGAVPEKIREKAELLSGYADGINVTDNQTAMVRMS
SLAACIFIRQMGLAPILQMVTRDRNRLAMQSDILGAYAHGIHAMLCLSGDHPHFGDHPMA
ANVYDLDSIQLIQTVRGMRDHGRFQGGDEILNPPKMFIGAAANPFADPFELRVMRLAKKV
KAGADFIQTQCIYNLEKFERWMAGVRERGLHEKVYILAGITPMKSAGMARYMKNKVPGMD
VPDEVVKRMAGVSKENQAKEGIKIAIETIERLKTVEGVKGFHIMAIEWEQRVPEIVESAG
LYPRPQL
>A0A3A4RX54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKTDSVVEKVLKSGQLVVTSECGPPRGANPDKVREKAEMLRGYVDGVNVTDNQTAMVRMS
SLSACIIIKQMGMDPILQMVCRDRNRLAMQSEVLGAYAHGINTMLCLSGDHIHFGDHPMA
TNVYDLDSVQAIQMVKKMRDEGKFQGGADIDTPPKMFIGAAANPFADPFELRVARLAKKV
KAGVDFIQTQCIYNMEKFETWMKGVCERGLHKQVAILPGITPMKTVGMAKYMKNRVPGMD
VPDEIVKRMGGVPKEQQAEEGMKIAVEQIQRLREVEGVAGFHIMAIEWEQKVPELVERAG
LLPRPKF
>A0A0Q4I9J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf226|TrEMBL
MTTITIPQLAEARRALEEPLFADLAGDVGISFEFFPPKSDKMDAQLWDAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLARLHPFEISVAAYPECHPESGGHDVDLDNL
KRKLDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFANACGA
EIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPSEKVAAA
>A0A2P7TKY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium UPWRP_1|TrEMBL
MKVTEHLANQTKTLVSFEILPPLKGKSIHSLYRILEELLEFKPPFINVTYHRAEYKYKPL
ENGLFEKTYIRKRPGTVGICAAMMYKYGIDAVPHLVCGGFARSETEDALVDLNYLGINNV
LLLRGDAVKPETHFVPEPKGNKNALELVQQVVNLNNGVYLEEELSNGYKTDFCIGVAGYP
EKHAEAPNMKADLQYLKQKVDAGAHYIVTQMFFDNNKFINFVNNCRSIGIEVPIIAGLKP
ITRKSQIYSLPSTFNISIPEELTDAVEACTTDEAVEQVGIEWAVQQCRQLIAFGVPCLHF
YTMSNTRPIQKIMKHLL
>A0A8H6K709|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum musicola|TrEMBL
MHIKAMLEESRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMFHFGPKFIDITWGAGGRIA
ELTCDMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRRAYKAGCTNILALRGDPPREKEK
WEATDDGFQYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDGDNFIRWVGKVRERGINVPIIPGIMPIATYASFLRRAKHMNCKVPEEWMTAL
EPYKNDDVAVREIGKGLVADMCRKIIAAGIHHLHFYTMNLAQATRMVLEELDWMPSSERP
LKHALPWKQSLGFGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPRSIKDVANIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSSHPVHGWGPPNGYVYQKAYLELLVHPDVYPEIVARIEKNP
DITYYATTKNGALKYNSSNDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGTDW
AHCFEAGSPSRVLIDRIMNEWYLVNIVNNDFHQKTALFDLLDGLAAKEYDDIPSEPQQTN
GASKSEAPNGNSASATAN
>A0A5Q0TBV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio algicola|TrEMBL
MSYSHAGHIDALNHNVADLAGKINVSFEFFPPSSEKMEETLWSSIHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKDQTGLIAAPHLTCIDASRDELKTIAKDYWNNGIRDIVALRGD
LPQSGGKPDMYASDLVELLKGVADFDISVAAYPEVHPEAKNAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVSNYKQAKRFADMTNVRIPSWMAKQYE
GLDDDPVTRQMVGASQAIDMVRTLSREGVKDFHFYTLNRSEMTYALCHTLGVRP
>A0A838I3F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthoniobacterales bacterium|TrEMBL
MHIKDIMRSDSPTFSFEFFPPKTPAAAESLYQTIRELEDYLPHFVSVTYGAGGSTRELTH
DLVERIKTTTQLNPIPHLTCVCHREEEIEPILRRYASSAIGNILALGGDPPRGLAYNKAD
DAFQHAEDLVKFIRSFNETGEHPDARGFGIGVAGFPEGHPATPNRLVEMDHLKAKVDAGA
DYIVTQLFFDNRDFYDFRERCELAGIRVPIIAGIMPITSMSGCKRIAELAAGARFPAKLL
RALQRCETEPEMVARVGVHFALEQCHDLLDNHVCGIHFYTLNRSDATRTIFDSLGIPRRR
QAHVATT
>A0A7X6GJ39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium A_SAG3|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGA
>A0A413UHK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM41-2BH|TrEMBL
MRVDEVFKQAASRGTAPVSFEMFPPKGELSLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMISSEFDTPSVAHLTCVGRSHADIAAKIGEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNASVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A2N5ZLT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Muirbacterium halophilum|TrEMBL
MSKLRELLENKEKVLTAELFAPKGIGMKNITRKLKILEPYIDLFNVTDNQRATMRVSSIG
LCAYLEREFGVETVYQLNCRDRNRIALQSDLLAASLLGLKNVLVITGDHHSIGDHLYTKP
VYDLDSVQLLQTIEKLNNGLDFSGNKLRGKPDIFAGATVNPVSRPMQPHLLKFKKKIRAG
AKFFQTQVVFDTDLFKEFYKEAKDEKVPILAGISLIKDVEFAKFINESVQGLNIPERIMK
RLSTGGDVSHTRIDVACEIIESLKDSCQGYHFMVFGLEKEIPIILKETSLVL
>A0A0U0YUJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides abscessus|TrEMBL
MTTNPLDRDGPVAELQDPGSIADRLTAVQPGEIAFSVEFMPPRDEAAEARLWRAARVFER
YRPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYAEQLVRLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPAALEERLLRAAGDGPEENRDEVRKVGVEVTTTMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTARG
>A0A4V8DDS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. MED-G68|TrEMBL
MSSALQSSLEAGAITITAEVMPPRGGDPSHALKMASALKGLVHAVNVTDGSRAVMRMSSL
AVARLLLDQGIEPVLQMACRDRNRIAIQADLLGAHALGIRNLLCLTGDPVRAGDQPKARP
VNELESVRLLQQVTAFNRGEDPVKGDLADGPTDLFAGAAADPQCSSWSGLLRRMERKKAA
GARFIQTQMVMDASVLERFCREIAEPMELPVLVGVFLLKSARNAGFINRMVPGACIPDNL
IARLEAAADPAAEGIQIAAEQVQRYLGVAQGVHLMAIKAEERIPAILNQAGVNLPG
>A0A158IDJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia choica|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRATGAQLAQLKPKFVSVTFGAGGSTQQGTLDTVIDMAK
QGLEAAPHLSCIGSSKESLRAILGQYRENGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFNIEVAAYPEYHPQARSPRADLENFVRKVQAGANSAITQYFYNGDAYFRFVD
EARKLGVDVPIVPGIMPITNFTQLMRFSEMCGAEVPKWIARRLESYGDDREAIRAFGLDV
VTNLCGRLVEQGAPGLHFYTLNGAAATKVICERLELKGV
>A0A2R8CGI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kushneria phyllosphaerae|TrEMBL
MSDACAPELSFEFFPPRTEAGQERLPEVYKRLAELNPRFFSVTFGAGGTTRDFTFDAVKN
MSRDTGVCTAPHLSCVASDKEDIRRLLAHYREHGIKRIVALRGDMPSGMMGIGELRYARN
LVDFIREETGDHFDLTVAAYPECHPQAQNFERDIDHFVDKVRAGADMAITQYFFNPDAYH
HFVDRVRARGVDVPIVPGIMPITNYTKLARFSEMCGAEIPRWVRRQLEAYGDDSESIQAF
GHEVVTRLCQQLLDQGAPGLHFYTLNQAEACTRLVADLSLEHARH
>A0A3R7UN86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium TMED96|TrEMBL
MKIIDHLKNKNDSSQFTFEILPPLKGQNLESIFNAIDPLMEFKPPFIDVTYHREECVYKE
LDNGLLQKHVIRXRPGTVGICAALQNKYNIDAVPHVLCGGFSKEETENLLIDLDFLGIEN
VVALRGDSLKSEVYFKPSVDGNSFASDLVKQIVDLNKGKYLDEEI
>A0A3N6NEI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natrarchaeobius chitinivorans|TrEMBL
MASEIERIDTGEGIRTLLEEPRFELMPFESMDEQLEHLPEGAEVAITTSPTLGLEATIDW
TERASERGYEIVPHVAARYVRDREHLEELTGRLTDAGVTDVFVPGGDREEPVGEFSSAYE
LLSALDELDSGFDDVGITGYPEGHAFLDDEVLAESMAEKEPYATYIVTQLCYDAETILEW
IEDVRDRGVDLPVEIGIPGVMKYQRLLGISKKVGVGDSVRFLQKTTGVLDFVRRFVGARG
MYTPADLVEGIAPYATDPYYDVRGVHIYAFNQVLDLESWRAETLDQHR
>A0A0Q0WAR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp. SDB|TrEMBL
MENIFKETLLNQSAFAVTWELVPGRGAKESVQEKTVTLARQAAGGGKICAVTLTDNPGGT
PAMSADFMGTEIVKLGIEPLVHFTCKDKNRNQIESQLYALDRAGVKNVLVMSGDYPVSGY
RGRPAPVFDLDPIHTLQLISEMNKGLTYPGIKGDIRHQPSNFFPGAVVSPFKATESEQML
QYYKLKKKIDAGAQFIITQLGYDARKFHEAFLFMKQSGFNLPLIGNIYILPYGAAKMMNR
NELPGSVVTDKLLTEVDKERTNSDKGEGARILRAARMYAILKGIGYNGVHIGGHNIKYEQ
VEKIIAQGEELTSQWKDLVQYFDYPIPGGFYYFDRDPKTGLNLDKPMARESRPLDAKIEL
TYGFSRFFHNLIFEPGKKLYGPMKGLSGKVTGKKMEKLIHKLEHWTKVVLFDCKDCGDCA
LIDVAYLCPMSQCPKNQRNGACGGSFEGWCEVYPGKKKCVYVRAYARLKKHGEEAQLSSN
IVEPCNWDLYQTSSWINYYLGKDHSSKKRGGNSSGN
>A0A848DMU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia bannensis|TrEMBL
MIVSTPTAIPSQIPGRLADALRTGRFTVTAEIGPPRGADVAPIRRAAAVLRDWVDAVNVT
DNQGATVRVSSFAGSLVALAEGVEPVMQMTCRDRNRIALQSDLLAAGAMGIPNLVLMTGD
RPEQGDQADAVGVFDLDSNGLMAAARSLRDEGTLLSGRTIDPPPRFLLGAVDNPVGPPDR
LAQKVAGGAEFVQTQFVFDVEAFSGWMAGVRDRGLDERCGILAGIGPIRSLRALEFMAGI
PGVVIPEALERRLRGVPGDQVAAEGVRACVETVQALRAMPGVAGVHVMVVGDERGVPEIL
EAAGLGPRVAAT
>A0A5K1K2A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ganoderma boninense|TrEMBL
MFEVADELGFVAGKRYVSAAICVCGEHAARAHAAASGAEIRGALVRALHELASTWAAFLL
WPFHAYGYDDRLHENENDDDRRLEPAGDETPTAESTASFRRRGHLKELVMARDNQRCFVS
SGLDDSVYYEGMPGVTRVVYCTTVSIIPAELLSSQSEPNQHLLTAEQDVMWGILRRFCGV
RDAAALAQQAQGPANTLLVHQWAARAFSMFLWWLLPTEPCLCFWRADGDGLSPYPSQT
>A0A231W2I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. KR|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A0N1N9Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium OK074|TrEMBL
MDNTPPPAPPTATLLDNFSLEMTGKDTAKLEEARPTIPPGTRINVTFLGNEDLTMRRAAA
LTVKRLGFVPVPHISARRLTSPAALEEFLAALQEDGTVDNVFVVGGDPTTPQGPYEDALA
VIRTGLLQKYGVTGIGISGYPEGHPAIPDEALWDALEDKAAELRERQLPGSVTTQFGFDV
DPVLSWVEEVRTQGIDLPIRIGVPGPAGIKRLMTYAARFGVGTSTSIAKKYGFSITNLMG
TAGPDKFIRALAQGYDANRHGDLKLHFYTFGGLKATSQWVADFRTREGI
>A0A4D9ET96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Platysternon megacephalum|TrEMBL
MVNEPHSASNGSASSRSDGSSSGSEGSKDSSRCSTPVLDAERHERLREKMRRRYDSGDKW
FSLEFFPPRTANGAVNLISRFDRMGMGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETILHMTCCNQTKEEITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVEGFNYAVDLV
KHIRCEFNDYFDICVAGYPKGHPEAESYEADLRHLKEKVSAGADFIITQLFFRSETFLAF
MKDCQAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKEVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVSGLHFYTLNREVATTEILKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIHRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELMSEESVFEVFTCYISGEPNREGQKVTCLPWNDDPLAAETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSENITALLKVLKTKKYELRVN
YHIVNVRGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEEESPSRMIIQYIHDNYYLVNLVDNEFPLENCLWQVMEDTFELLNCPTEQ
>A0A7T4T7Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia ginsengisoli|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLASLKPKFVSVTFGAGGSTQQGTLDTVIDMAK
EGLEAAPHVSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFANKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLTRFSEMCGAEVPRWIARRLESFGDDRESIRAFGLDV
VTDLCERLIDAKVPGLHFYTLNGAAATKAICERLGA
>A0A1Y5ZYI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKETAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8E2RDV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola|TrEMBL
MTTNARQDRLTHPVTHRLASTITDAYSLEVSATDIAGLSAAAPAIMRGATIAIPYLPNQD
DAARLAAACMVRKLGFAPMPHLSARRIGSRDALHAFVRRAVDEAGVERCLVIAGDPPSPI
GPFPDSVSLIDTGVFERCGIRTIAVAGHPEGHPGMPASERWDVLERKCRSIAERGMAPLI
VTQFAFDADLVLTWLHALRAHGIAHPVRVGVPGPAGVAVLARYAARCGVGACAAMLSKYG
ISLGKLLGTAGPDRFVDRLATGLTGAHGEVSLHFFPFGGIAQTVAWVEQYRARTVPHRAD
>A0A2B1DFM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKRLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAILNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A150C3D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRATLNVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKDAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2A8XL13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENRVVQINKAAVKIAKASITDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAIANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGVMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKDAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1H0YI24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia fungorum|TrEMBL
MNPIELSFEFFPPKTQEGVEKLRATRAELATFKPKFVSVTFGAGGSTQQGTLDTVVDLAK
SGVEAAPHLSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DAHKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VADLCQRLIDAKVPGLHFYTLNSAVATKAICERLGA
>A0A6N7QSA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gracilibacillus thailandensis|TrEMBL
MSNLISHLQNKLVVADGAMGTLLYSHGVDRCFESYNTTHPDEILHVHQTYLDAGAEIIQT
NTYGANYIKLTRFGLEDQVHQLNTKAVQLANTAAKDRAFVLGTIGGIRGVQKIVASKKEI
IRSFKEQLFSLLLEGVDGILLETYYDFEEIKQVLEIARQETDLPIIANVSMHEPGVMENG
IQLPLALQTLENIGADVVGVNCHLGPHYMIKALESVPLLEKAFLAAYPNASLPAYQNGKL
VYNQHSHYFERCAKEFRDQGVRLIGGCCGTTPEHIRALKEGVTGLEPITEKEIKQVTFTK
NTTEQQPPLRTTLADKARKRHTVIVELDAPKHLDIAPFMNGVFALEKAGVDAITLADNSL
ATPRISNLAMAVKMKQAGCHATPLIHLTCRDRNLIGLQSHLMGLHTLGLHEILAITGDPT
RIGGFPGASSVFDVTSLELTKLIKQSNQGLSFSGSSLKTNTHFQVAAAFNPNVANLEKAV
KRMERKIKHGADYFLTQPIFNHEQIILLHRMTKHIDQPIFIGIMPLTSHRNAEFLHHEVP
GMKLSDEVRTRMQRHDNRQDSLQEGIQIAKELITTAMNYFNGIYIITPFMHYPLTVELTK
YVHQQAKIVTKI
>A0A2A2P2M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus toyonensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2W5LDS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium propinquum|TrEMBL
MAPRVSASAPLDDSSDNAQPQPRTASERTALSFEVIPPRHDADEKKISHLLETLESYRPD
YISVTSSRRSGWLDGTAKFISRIDRETTMRTLAHLACTAGTKQEMIAWINRLIDSGVRGL
LALRGDLPEGEVSLPADHLQYADELVRLIRQVESQQAARFAAGRLAVAVASYPNGHYQAR
TDDENFDVLLSKQRSGADLAISQLFFEAEDFLQFRRRAELAGVRIPQIPGIMPITSVRRL
RRMAEFSSLPVPEHLVRRLENARDERAEGIAITAELVQAMVDNDVGSLHIYTHNNAEVTQ
ELLDAVGIRPPTAPG
>A0A7X8SD63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. P28RR-XV|TrEMBL
MSSRSESVSDGIRVSFEFFPPKSEEAEQQLWTTVADLSDWEPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLAAGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVGALRERGDFDISVSAYPEKHPESRDTSADIDMLKRKAENGADRALTQF
FFDNDAFERYHDRVRAAGIRIPIVPGIMPIQNLTQLKRFAGACGASIPSWLDERFDGLDE
NVEERAKVAADVAAEQIQDLIGRGIHEFHLYTMNRSALVSAVLERLGLQRKVDARAGAAA
>A0A8E2RG31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola|TrEMBL
MTPLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWISKKMQSFGDDAEAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>C0FVL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia inulinivorans DSM 16841|TrEMBL
MRLTELLNKDEVTISCELFPPKQGAQLENYKNIVKDMAALKPAYMSVTYGATGGTSDYTV
KLAEEVRNNNIPALAHLTCASSTREKVASVIEELKAANIENILALRGDIPANADFPLPDQ
YKHASELIADIKAQGDFCIGGACYPEGHPEAATIFEDLDHLKEKVDAGCEFLTTQMFFDN
NILYNFMYKALKKGIDVPIVAGIMPVTNASQIKRITSLSGNMVPPRFLAIVDRFGDNPTA
MRQAGIAYATEQIIDLIANGVNHVHIYTMNKPDVAGEILDNLSNIYVR
>A0A2T1GEC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chamaesiphon polymorphus CCALA 037|TrEMBL
MNNFRQAATAGEFLITAEVAPPKGGDVAHMVQMANCLKGRVHAVNITDGSRAVMRMSPFA
ASLILLQQGIEPVCQFACRDRNRIGLQGDLLGAHALGIQNILALTGDPIKAGDYPTAKAV
FDLEAVRLLKIVDNLNRGLDGNDKPLPDGAVDLFVGAAVDPQSKSLSGLQRRFEQKVAAG
AQFFQSQLITDFDILDKFMDRIASAYHKPVLAGIFLLKSAKNAEFINRNVPGVDIPQEII
DRLARSPEPLREGIAIAAEQVRLASKLCQGVHLMAVKREDLIPQILDLAGIEPLNLES
>A0A1A2VUH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium scrofulaceum|TrEMBL
MMSAGLGCPKRMVFGPCGGVRPDGQCEMRPGPCAFDDVVVWSGPQATPRPVRAPLVLTDF
SSTPFDRDDIAATAAALAPGCDAVLVGEHQNKPDFPPTVMGSLLLDAGVTPWITLSCRDR
NRVVLEQELRGLVSVGVETVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASTGAVAAV
PETPTAPPVHARPARLVEKQRAGASVAVLNHVPSPGLVADFMTAARAKGLTIPVIAAVAV
FTDSVSAAVLQGLPGLELDRDVTERVLGAPDPVAEGIAAAVSEARALLSIEGVEGVNVSG
LASASGPRVGAEIKGEVGRRIRAEGK
>W5YH35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter similis|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQTVRNKLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRQEIGELLDVYKENGINRIVALRGDMPSGMGAAGEMRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARSAEDDLQNFARKVKAGANSAITQYFFNADSY
FYFIDRLEKMDVTIPVVPGIMPIINFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVITDMCEKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISEQEKISF
>A0A0F7M267|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spongiibacter sp. IMCC21906|TrEMBL
MSKRFSFEFFPPKTPVGREKLQTVRSELATLDPSFFSVTYGAGGSTRDNTKSIVMEAKAA
GLAVAPHLSFGGDDEDTVLALLKEYQNAGVDRIVALRGDIPSGMGASRLVYAQELVEFIR
KHTGNHFEIEVAAYPEIHPDAPSYVADIQFLKQKLDAGANSAITQYFFNADAYFYFLEDC
EKAGIDKPIYPGIMPITNFTNLARFSRNCGADIPRWLTQKLEGYGDDKQSVIEFGTEFVT
EMCQILMEGGAPGIHFYTMNQVEPVKSILQELQS
>A0A249LIZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Planktophila lacus|TrEMBL
MKEIGEGVTYSFEFFPPKDPEGEERLWSAMRALEPIAPDFISVTYGAGGTTRDRTIRITS
EITQRTHIPTVAHLTCVGSTRDELIEILARYKQSGIHNILALRGDPTGGPRAPWTPTPGG
LNHADELVTLAAEVGGFTIGVAAFPDGHPASGLNFDEDIEVLLRKEKAGASFATTQFFFE
VDKWRALVDRLSARGSKLPIIAGILPVTNVAQLNRMAELSGTPIPPAIAARFEALKDSPD
DVRKLGVEIATGLCEDLLDAGVPGLHFYTMNTSSATREIFEQIKDKKRG
>A0A1V4XV08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophus sp. PtaB.Bin138|TrEMBL
MSALQNILSRLVETPLIFDGAMGTMIYDKGVFIQTCYDELCLTSPGLVREIHEQYAKAGA
EVLETNSFGANRIKLRPYGLAEKVAEINRAAVKLARQAAGPDLYVAGSVGPCTQGGQVIA
GGEIAEVEAAFREQVKALAGEGIDLLILETFSDLKELQLAARIAREEGVPVLASFAVDEE
GETAAGTPAEKLAAALEADPHVDAIGLNCGTGPAGMYEALLKILPVVSKPVVVMPNAGMP
RTVGGRTLYLANPEYFTEYAKKFIELGVRGIGGCCGSTPEHIATAARAVRGLSGVRRHIE
VVSRRPAPAQQNIIPTAEKSRLAAKMFSGRKVTSVEILPPRASDFSNMLAKVRRCHEAGI
DAINIPDGPRASARVSPMITALVILKEVGIEPVVHYCCRDRNLIGMQSDLLGGYAVGLTN
YLIITGDPPKLGNCPEATGVFDVDAIGLTRVVSNLNAGWDIGGSPVDPPTGILIGVGANP
CAVDLEREIDRYFQKIEAGAEFAITQPVFDAEALLRFLDRVERYAKRIPVLAGVWPLLSY
RNAEFMNNEVPGVVVPQEILRRMAGCGSGDESRHAGIEIARTICAEIHDRVAGFQVSAPL
NNVEIALAVLGKSEG
>A0A7C7MHF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MDPQSGGKTVAKVTDRCFEATGHSAFICDFSPPRTGDPESFTQPNLDADFISVAYNPGKA
VRVNSAMLAAAIKGETGKDVLFTLATRDMNKLALESLLLGGQMLGLENVVVVQGDPFTQR
DLTRVKDVSDFTPTRMISAIAAMNLGTDYREGQLRSPTRYCIGATLDLGRGIGSEAQLAH
RKAQAGAQFFISQPIFDVADASRFRQAFEESAGHDSELPVFFGLQVLEQDGIIFSSVPET
VRQELEQGRPGVEIALELFHRFQQAGLHNIYLVPPIRRGGARGYGAAREVLAGVERL
>A0A7Y3ZXH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio pectenicida|TrEMBL
MGYTHAGHIDALNQNVAELSDNINVSFEFFPPSSKKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKTQTGLVAAPHLTCIDASREELIHIAEDYWANGIQSIVALRGD
IPPGGGKPDMYACDLVTLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKV
>A0A4R5M0F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia silviterrae|TrEMBL
MKPIELSFEFFPPKTPDGVEKLRATRAQLLTLKPRFVSVTFGAGGSTQQGTLDTIVDIAK
EGVDAAPHLSCIGSSKESLREILRQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVAF
IREETGDAFHIEVAGYPEYHPQARSPRHDLEAFAKKVKAGANSAITQYFFNGDAYFRFIE
DARKLGVDVPIVPGIMPITNYTQLMRFSEMCGAEVPRWIAKRLESFGDDRESIRAFGLDV
VTDLCRRLIENGAPGLHFYTLNAAGATKAICERLDL
>A0A7K5N2M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chroicocephalus maculipennis|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7R6YY76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L-2-11|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPIHNFTQVGNFSARCGTLVPAWLAERFD
GLQADPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A7R6YYL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L-2-11|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDQIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHLLHDEITETQVDMVK
TAH
>A0A7D6EYN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium IMCC26103|TrEMBL
MEMRMSRVGEAVTYSFEFFPPKDQEGEDRLWSAIEALEPIKPDFISVTYGAGGSTRDRTI
RITSEITAHTKLPVVAHLTCVGSTRDELLEILTRYKGAGIHNILALRGDPTGGPRAPWTQ
TPGGLNHAEELVSLAADFGGFTIGVAAFPDGHPASNGDFAADIETLIRKEAAGATFATTQ
FFFEADKWKSLVDKLAARGSQLPIIAGILPVTNVNQFNRMAELTGTPIPAAISNAFEKVR
DNPEDVRKLGVELATQLCEDLLVAGVPGLHFYTMNTSTATREIFAQIKDKRRE
>A0A7T0KMD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium qintianiae|TrEMBL
MNERFPSTRLSASAPLDRLDEDPATEPVLRPARSRTALSFELIPPRHDADTALLDTLIAG
LAEYNPDYVSVTSSRRSDWLEGTAALISRIAETTDLKPIAHLACTAGTRDELTVWIRTLI
DAGVRGFLALRGDLPEGEAKLPDGYLPYATDLLNLINEVQEEQAFRLAAGKLALSVACYP
SGHAESKNADMDLDVLLAKQRLGADFAITQLFFEAEDYLSFVEKSRLAGVRIPLIPGIMP
MTSLRRVERMGVLSGIKVPECVTRRLSDASTAEEEYEIGMQMSADLTRTIVDAGTGGLHI
YTHNNLAVTRDLLSRIDI
>A0A6I4ZI92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTTVVEHRFQCTDRVQIVADFSPPKGTDPALLDETGRLDADFISVNYSPGKSARVNSAFA
AAWIKQNAGKEVIFSLSTRDMNRIAAQGLLLGANMTGLENVVVLRGDSFTKTELAITKPV
DDYTPTGLIRAIADMNRGIDYKGLKLQDPTSFCIGATIDLARSMDRQVELTRKKVETGAQ
FFLLQALFSPERLTEFLERYADKYGEELSALICCGVQVLVEDGVTFGALPDWVTTSLRKG
RSGEDIAVETASRYLDAGQRSIYLLAPIYRGGRRDYVACRRVIERVRKL
>A0A7V2KP99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MTRSLREALNSGKFVVTSEIGPPKGTNIEKMLHHIDLLKDKVDGLNVTDHQSSVMRFPSL
GGCLFIKERGGEPILQMTCRDRNRLALQAELLLAHTRGIRNVLCLTGDAVPVGDHKEAKG
VFDLDSVQLLRAIRLLESGKDLGGNNLDGAVDFCAGAIVTPEAQPIEPQLIKFAKKVEAG
AEFFQTQAIYDLDNFAKFMRYARQFPVKVLAGIVLLVSPRMAKYMNDNVPGIFVPQNLID
ELSSVPKEEALKKGIEIAGRMIAALRRDSLCDGVHIMAIGREEVVPDILAAAGLLPQEGK
KEG
>A0A848MQS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rouxiella aceris|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTPEMENTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATPDELRQIARDYWQSGIRHIVALRGD
LPPNSGKPEMYAVDLVHLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCASAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSMFA
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPEIASA
>A0A7V2QK82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSLKSSLEAGKFAITCEVGPLKGTDTTEIEEVAGLLTGRVDAANVTDQQSSVMRLGSMAT
CHLIKGKGLEPIFQMTCRDRNRLALQSDLLSAHVLGIENVLALTGDLPALGDQPQAKPVY
DLDSVQLLWTIQRLNEGFDINGNELQGKTDFFAGAVVTPEADTEAKRELQFYKMEKKIAN
GARFFQTQAIYDPDTFARFMKRVEGFKIPILAGIIPLKSAAMARFMNKNVAGVFVPDELI
DKMAKAEDKTAAGIEIAADLMKSLKGICQGVHLMAIGWEKKVPAILDAAGL
>A0A3P9NVC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Poecilia reticulata|TrEMBL
MVNQVQQVDGSWQSCRGDSSGGSNSSAESSNESSRCSTPVLDADRSDRLREKMRKRTESG
DQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGDDWENEEGGFNFAV
DLVKHIRSEFDEYFDICVAGYPTGHPEAESYEQDLQHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRAAGITCPILPGIFPIQGYQSLRQLVKLSKLQVPEEITKIIEPIKDNDAAIRN
YGIHQAVDMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWVEDPRRPLPWAVSANPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLQMWGEELKNEQSVFEVFTCYITAQPNRNGQKVLCLPWNDEPLAPETNFLKDELEKVNR
XGVLTINSQPNINGKPSADPVVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVHGHNMTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKVHRAKXNLRLMQ
EVSRGKLQIQFTLSDLPKVLAVGESALFSLLWQIXKIKKTFCATD
>A0A831KL83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKISEILSRNRPALSFEFFPPRNPESEHVLDETVGKLRRFNPDFVSVTYGAGGSTREKSL
YWTTGIREKYGLNVMMHLTCIASSRRDIQDICRRLRMEGISNILALRGDPSRDLPDYRIQ
KDFRFAYELVEYLRETDDFSIGVAGYPEGHLDAVSLGRDIENLKRKVDAGADFIITQLFF
DNRHFFDFMDRVAAAHIEIPVIPGIMPITNAGQVQRFTEMCGATVPGEIKGRIDNTEDVF
RVGVDYAIEQCKELLDFGVPGLHFYTLNRNRATEEILAGIGKVLERE
>A0A7V3SC53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MAQSFREALNSGKFIITSEIGPPKGTNLEKMLHHIDLLKDKVDGINVTDHQSSVMRFPSI
GGCLAIKERGGEPILQMTCRDRNRIALQAELLFAYTRGIRNVLCLTGDAVPVGDHKQAKG
VFDLDSSQLLHAIRIMESGKDLGGNDLDGKVEFCAGAIVTPEAKPLEPQLAKFEKKIAAG
AEFFQTQAIYDLDNFAKFMVYARQFKVKILAGIILLTSARMAKYMNDNVPGVFVPQKLID
EMAAAPKGEAVKTGIRIAGRMIAEIKKNNLCDGVHIMAIGKEEVVPDILKEAGIER
>A0A6I4ZHB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKSGSRLERVLRAGHFAVTAELLSPDSADPQAVLDHAQVIGDSCDAINATDASGATTHMS
NVAVAALLRRAGYDAVVQLACRDRNRIAMQGDLLGIAALDVRNVLCLTGDGVGTGDHPEA
KPVFDMDSITLLRTARILRDKGQFLSGRPIDSPPRLFLGGASNPFVPPYDFRPLRLKKKI
EAGADFIQTQYCFDVPRLRSFMERVVDMGLQERAFILVGVGPLRSARVAYWMRENIPGVV
IPDAVIRRLLGAGKRSRTEGKRICIEIIQQIKEIPGIAGVHVMAYRQEHLVPEILDEAGL
LPRPEPELFDGIHASSADVVESNRC
>A0A1H0QSE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium testaceum (strain StLB037)|TrEMBL
MTSLPLIDACPKRMEYGPCGGVGFDGSCEIDATHRCAFLHRPTVPWTGVDRAVVPGPSPR
TAAATQTLAALDTRPWVVADLPARALSVSSIDACAEILAGEVDAVLAGDAGSARVQFPPA
YRAHLLQRRGLRVWTGLNMRDRNRVAIEGELAALAVEGVAGVHCVTGDHTRTGHRPDAAP
VFDLDSTEAAALARAAGHVVSVAASPAAPPVDRRAARLREKVRAGADVCFVNHAGGAEPV
RRFVEDVGGGLRFIPCVPVVVDHASADLLESFTALVLPEGFLERVRGARDPRAEGIALAV
ALAEEMLALPGVVGVNLSGGRDGAEDSYAEALVEVARRLR
>A0A0D7EJT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas palustris|TrEMBL
MSERPQQLPAISFEFFPPKTEEMDRALWESISRLAPLAPTFVSVTYGAGGSTRERTHATI
ARILKETALIPAAHLTCVGAAKSDIDDVVARYHEVGVRHIVALRGDPENGIGSAYVPHPH
GYKTSADLVASIKKRFPDIDVTVSAYPEKHPESATFDADIDVLKAKIDAGATRAITQVFF
DNDLYFRYLDRVRARGIDIPILPGIMPMHNFKQARNFVTRAGTTVPDWLADKFEGLDDDA
ETRKLVAAAVAAGQVQKLAKHGVDTFHFYTMNRADLVFAICHLLGLRPNGARKAA
>A0A443I829|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Byssochlamys spectabilis|TrEMBL
MEKITDKIAALPPDANFFSLEFFPPKTQMGSANLQARLERMAQALRPLFVTVTWGAGGTT
AAKSLELAEICQRQLQLTTCLHLTCTNMDRKLVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKEFKYAVDLVRYIRKVHGDYFCIGVAAYPEGHPGESVQDPQSPEHDLPYL
IEKTTAGADFIMTQLTYDIDAYRKFEDLLRNHESGVFKTIPIIPGLMPIQSYNILTRVTK
LSHVKVPKDVLSRIEKVKTDDDAVKRTGVDIVSEIVDKMKDLPCPGPRGFHFYTLNLEKS
VSFILERCDLIPPSTDAADDDDRDADGVVIVEAPKDAPLTEVQKRSFSRRRASSINSQPH
NRLIVDKPSVPSDGSSRGSTTHETAALSAGLPALNPPPRSTTLQISEGLGSLGREATWDD
FPNGRWGDARSPAFGEIDGYGPSLHVSAAVARRIWGYPVSRDDISTLFRRHVSGELHMVP
WSEGGAEENSGGLNPETLTIRPELLKLIEGRGWWTVASQPAVNGVRSDDPTYGWGPQKEG
FVFQKPFVEFFCPNKDYQTILKPLLQKYGDEEFAWFATNATGELESYISTQSNGDESERD
QVHNGVNAVTWGVFKGKEIITPTIIEEVSFRAWGEEAFRIWDEWRRVYPRGSPTERFIDE
TKNDVWLVCVIGQRYGAGTEPGSKEEEDEVKMLWRVLAGEQ
>A0A3D1LYU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MNQRMREDLEKAYMEIIPVPGIEERLESLQENSHVAVTCSPTKGVDETIELSEKLIKQGF
QVIPHIAAKCVSGKKHLETIVKRLDTLNIKSIFVPGGDLPQPTGEFNNAYDLLKALHKCG
HNIENIGIAAHPEGHPDVSEETLMEALHMKKELADYIVTQMCFDADILGDWLVRINQQGI
RLPVWVGLPGAIERGRLLKTSLRIGVGDSMRFLRKKSQVAAELMRSSIYNPDKLVKSISE
YKDIDNSNLAGYHIFCFNQ
>A0A344PH81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus suum|TrEMBL
MSPRPRLSFEFFPPKSLDGAFRLSEAARMLAPYKPGFVSVTYGAGGTTRQLTHEAVTAIG
THYGLNVAAHLTCVEATRDETLAIVDSYAKEGVREIVALRGDMPGGGPFVAHPDGFSGSV
DLIEAIAARGDMTIRVGAYPEPHPDSQGTAADIAWLKRKIEAGATSAITQFFFDADTFFR
FRDACAAAGVDAPIVPGILPIQSWDGAKRFAARCGTSVPEGLDEAFTAAKAEGREQDLAA
DICADLCRRLGDGGVQDLHFYTLNRPEMTRAVLDRLGIPPEGDALAAVA
>A0A523PQA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKLEDEPQNPGDPLPVLPGHSSGGRLERVLRAGQFAVTAELSPPDSADPEEVYVRASVFD
GFVDAINATDGSGANCHMSSVGVCSLLTRVGYGTVMQISCRDRNRLAIQGDVLGAAAIGV
GSVLCLTGDGVQVGDQPEAKPVFDLDCMSLLAMIRLMRDESQFLTGRKLTSPPRVFLGAA
SNPFAPPYDLRPMRLAKKIAAGAQFVQTQYCFDIPRLKEFMDRARDMDLHRRCFILIGVG
PLASANAARWIRTNVPGVHIPDAIIDRLAGAKKQKREGRKVCMEMIQQIREIEGISGVHV
MAYRQEEAVAEIIDASGVLEGRVPWYPNRDKNLGLKKAIL
>A0A349K7A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MVMKSVLEAINKRGRKPFLLCDFSPPKGGNADLLLESYALNPDMFMVGYAPGKSVRLNPI
FAADWIHSKTKIPSIFTVSTRDMNKSAMQSLLLGAELMGLPNVLIVKGDKFSAEDLNLQS
EVYDFTPTELISDVKAMNERRDFRGNELTYPTRFCIGAALDLSRDWEKESRLTKTKITRG
CNFIVSQPTFDPELPSKFLSFYEKTIGEKLKIPVMWGIQMVEKDTISFANVPKWVH
>A0A0S9DS24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agreia sp. Leaf244|TrEMBL
MESLLTPAAAHAGCPKNMEYGPCGGVDFDGSCEVADFRCVFLGDPLVTWHGASPPEPDVV
PRSSGAAEMMALMNTRPIVVADFPARAMDAESLAECAALLAGPVDAALAGDFGKARVQFS
PSYRASLIRAAGLQVWTGINCRDRNRVAIEGELAGLAHVGVAGVHCVTGDHTLLGSRPDA
APVFDLDSPQVAALARAAGHLVSVGESPTTPPVELRAARLLEKTRAGADVCFVNHCGGVD
AVGRFVRESHDLGVTARFIPCVPMVTDHASAQLLRSFTTLVLPEGYLDRILSAADPREEG
IRAAVELSLELLEIEGVAGVNLSGGAGPGREAEFAIVLAETAQRLAL
>A0A315XAC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSVPFAEKLDAGQFAVALEITPPQRDLPKVLLRRARLLGAAAQAINVIQRPGRQSSLDAS
LNLKAAGMEPAWHLVTRGRTREELQADLARAAAGGIGQVLCILGDHTAGEAADGVTIRDA
VTMTRETLPGAIVGATLNQYGRDEQAVLKNLLPKLRAGATYVQTQPVFELEPLERYAQAI
DRALPEARVIAMAMPLVSLEAAMRIEERLGVSLPPGLKDVLAGGDPEAAWGTFTATIRAL
AESPLVDGVAIMTFEMDAPAEMGERILAALRAAGVA
>A0A1V3MXF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. CZ-UAM|TrEMBL
MKITDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTEGGHAFATDLLEQVTDMNKGKYLHEDIITSEKTDFCIGVAGY
PEKHFESPNFNTDFKYLKQKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVASCKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLA
>N9D5J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter calcoaceticus ANC 3680|TrEMBL
MSHISPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFEHFLEQAKAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGSFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHAYSQQILACVMPLTLGRANFMVKHKVAGIVITAHMLKVLADEKLAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQTLLESYIEQYRHLELEVLEELWNSLWQVT
TGKEFSPEISRFSRQPTSKQLIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWENSLVAK
ALLKTEVVSKHSLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVAQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A7R6WZJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 113-3-3|TrEMBL
MNQFRFSRRPDIGDKVKVSFEFFPPKNDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTIGRILNETSLTPAAHMTCVDAARHQVDAVIQEFVDMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A7X3ZZ63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boseongicola sp. SB0677_bin_26|TrEMBL
MPLSSLSFEFFPPKGIRASLRLWEAVSELAPLGPDFVSVTFGAGGVQHGLTLDTVKAIKK
HFNLVVAAHLTCCNATREETLEVAESYSAAGVREIVALRGDPPTGTGTFRPHPGGFEDSC
ALISALAELKKFSIRASAYPDPHPDATGPGADVEWLKRKVDAGATSAITQFFFEAESYFR
FRDACDAARINVPIIPGILPIEDWTRMKRFARRCDAHVPAWLADAFETAVRDDRHDLLAI
SVCTELCSDLLDGGVENLHFYTLNKPNLTREVIRALRTAPTASLRYVA
>A0A2H9M686|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeum sp. CG03_land_8_20_14_0_80_32_618|TrEMBL
MSLLRENFSRKFTATGEVSPPPCPDKTLFAREVEEMKPLMGRILGVNVVEGPGGRVLMSS
LGASIYMIQHGVEPILQQVVRDKNRVALQNDLISASIFEIENVLSIAGDHPACPASDNPK
SKPVYDMDSTTLIVMLKKLNEGKLWNGKDTNYENKNLNAKTNFFIGTGLSPTSSPLDGEI
YKVKRKLIAGCDFFQTQGVFDIEPIINFLNLYEKTIGEKISDKILVGIVPIWSYGMMKYL
LTLPGIVIGEKFRNDVNEARKKQKETGQKGLIEEIGVNLCVDLVDKIKGLGVKGVHIMPV
GNLHAMKEILDKSGL
>R9T406|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanomassiliicoccus intestinalis (strain Issoire-Mx1)|TrEMBL
MSHLKDVLESGKFAVTAEISPPKSASCETIRKKAAMLKDCVDAVNLTDNQTAIVRISSFA
SSLACLQEGVEPILQMTCRDRNRIAMQSDVLGASAFGIHNVMCLSGDHQSFGNQKEAKNV
YDVDSIQQLMIFNKMRCEGRVWGGDELKEKPELFLGAAANPFADPFEFRVQRLAKKITAG
ADFIQTQAVFDVERFRNFMSSVCDRGLDKKVHILAGVMPLKSYNMAEHMKNNVSGISLPD
EMVSRMKSAADPKEEGLAICHETIEEIKKIKGVHGVHIMAISWESVVPRIIEDAELRN
>A9M6B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella canis (strain ATCC 23365 / NCTC 10854)|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATCEDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMVGIRPKTQAAL
EVA
>A0A023XXF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium japonicum SEMIA 5079|TrEMBL
MERNLWETINRLAPLDPKFVSVTYGAGGSTRERTHSTITRILKETALLPAAHLTCVGASR
GEIDEIVDRYHEVGVRHIVGLRGDPAGGIGTPYSSHPDGYQSSADLVAGIKKRHGDIEVS
VSAYPEKHPEARDFDADIDTLKAKVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIV
PGIMPMHNFKQARNFVTRAGTTVPDWLAEKFDGLDDDAETRKLVAATVAAGQVQKLAKRG
VDTFHFYTMNRADLVFAISHLLGIRAKSAQKAA
>A0A1G5CZ68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. LKL04|TrEMBL
MSIIQTPSVTTVPVSFEVYPPRSDASDAALHRTIARLAEVEPSFISVTYGAGGSTAGRSL
EVLRHIRRETRVEPLAHLTCVGNSYREATALIREFLDAGIRSFLALRGDAPQGAPEDPDG
AGDLESAAQLVQLIDRVQAECSPYTEEPIPGVPGAARVERRRHVDIAVAAFPNGHPRSRY
PAEHIDALLAKQAAGATLAITQLFFHADDYLAFVSRARAAGVVIPILPGIMPITSPSRLA
RIVELTGQPVPGALAVDLDVEPTAEGRREVGVRYAAGLCRAVLEGGAPGIHLYAFNHHRT
VLATLAEAGVITPTEETS
>A0A4V2V3Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Martelella mediterranea|TrEMBL
MLPIFENEKPMTDTRTLPASIEVLPSRFKAADGFLFPRGTRVYLTDIGAPETEAKMLDAA
RELSALGHQPVPHIAARRIASEDLLERRVSALANKAGVSSMLLIGGGLERPIGPFESVMA
LLETGVFERNGITDLAIAGHPEGSPDFSDTVADAALLEKQAFAARHGISLRIVTQFAFDA
QAILDWETHIREIGVDIPVHMGVAGPAGLLTLIKYAKMCGIGKSASLLAHQPKRLMGLGA
GYSPDNLVEPVEAEQAAGRHNGIAQIHVFPFGGLERSAAWLTGRGSWDKADDRPPLR
>A0A143WMN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tremblaya princeps|TrEMBL
MPGLSFEFFAPRSHAGSIRLMCAQQILSRFVPRFVSVTRSASIGQQAHIDTIASTLSVFP
RTAPHVLFCQCPRALARELRAYELLGIRHLVLLRGDNGIAPGSLGAPELVSLVRRSYGEA
FYIDVAAYPDGHPMSSTIFEDVRALARKVRCGANSAITQCFYNPDAYYRLQDELQRLGVS
LPVTPGIMPVLSHDYMARFILPSGVDVPAWILKRLEALRYCRASVLEFGTDVALSLCESL
AARGASDFHLYTMNDHRAVWRVCEHVLGSADACHRSGT
>A0A4Q3DDN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium|TrEMBL
MAAPLFADVAGDIDLSFEFFPPKTEKMEETLWESIQALSPLGPRFVSVTYGAGGTTRERT
HNTVARIARETGIPAAAHLTCVEATREEIDQVAHEYWEAGVRHIVALRGDPPRAGEKYRT
HPGGYENAADLVAGLSKLHPFEISVAAYPECHPDSPDAIADLDNLKAKIDAGATRAITQF
FFEPDTFFRFRDDAAKAGITAEIVPGIMPVMSFAAVQKMSAMCGTDVPGWMARLFEGLDD
HPGARQLVAATLAAELCRKLYAGDVRQFHFYTLNRAELSYAICHLLGVRPKL
>A0A4Q7MHG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces ramosus|TrEMBL
MAETGQDAGGADCRPSVSFELFPPRTDAAALALGRTIDRLAEADPAFISVTFGAGGSSRD
RSLTVLRYMLEHTDVEPMAHLTCVGSSHAEANRLVREFLDAGITSFLALRGDPPEGADPD
AGIRDLDSAAELVQLIHRVQEEREPFAQVGIPGLPGVSQIGERPRPERVAVAAFPTGHPR
SRGPAQDVDTLLAKEIAGANLAITQLFWHADDYLGFVARARAAGVTIPILPGIMPVTTPA
RLRRLTELTGVEPPAELEIDLEIEPDPEAQAELGIAYAARLAADVLDGDAPGLHLYTFNR
HEAVLDVLDRLGIGANDRLVNERNTTER
>A0A249PUG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium fredii CCBAU 83666|TrEMBL
MNARTLYPAERGNLRLSFEYFPPKNEEMEIQLFQTVADLSSFAPAFQTVTYGAGGSTKAR
SLTTVKRMIGEMGLRNTAAHLTCVGAPKAEVDAVIDEFVACGVRHFVALRGDPQGGIGSA
YQPFPGGYESSAALVNALRARGDFEISVSAYPEKHPESSDVAADIDMLKRKVDSGATRAI
TQFFFDNDDFERYLERVRRAGVQIPVVPGILPINNLTQVIRFAGLCGSKVPEAIVSRLGH
LDDQPEERFKEASHIAAEQIVDLARRGVRDFHLYTMNRSPLIAAVCDLVGYGRRPANHTA
APSYRAVATA
>A0A2W2C1Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiangella anatolica|TrEMBL
MALGLPSTMPGGARTIRELLAAGGRSFSFEFFPPKTEQSETAFWQIMRDLERLQPTFVSV
TYGAGGTTRDKTVRITEGIARDTTLTVVGHLTAVNHSVAELRNVIGQYADAGVRNFLALR
GDPPGNPQGEWVKHPDGFEYAEDLIRLIRANGDFCVGVAAFPDKHPRSPDLETDARFLAR
KFQAGADYALTQMFFHADAYLRLRDRVAAAGGDAPIIPGIMPVTNVRQIQRFAQLTAADF
PQALADRLLAVEDDPEAVRAIGVEVATELCERVLAEGAPGLHFITLNKSTATRKIYQNLG
VAALS
>A0A1H1IXN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiales bacterium GAS113|TrEMBL
MGDRAMMPASQVPQDVVPPQAQDTVPTQAQDIVSQIVAFMQRASMEATRPTPADAEMLSA
VLPHGTDIFLSAVPRRPRGEVIAAARAIRTAGLNPVPHIAARAYPSLEAAREHLARLRDE
ADIRALLVIGGDLDQPAGDILEARQLIESGVLPALGIERVGIAGHPAGHPRMSDEELESV
LVTKIAAAQSSGLEVEIVTQFCFEPATIIDWIAWLRRRGVNLPVRIGLAGPTSLMTWLNY
ARRCGVRASAEGLARRSGLVKHLFNAVAPDSILRALAQARQAELPSTDRLGDVSAHFYSF
GGIGPTARWVASAMHGAITLDKEGGFQVEHE
>A0A1G3QI96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium RBG_13_51_14|TrEMBL
MDLKESFIKNRFVITSEIQPPLDEDFRELIENIEKIRGRLDAVTVPEFDIEGVVADSIGT
CGILRENKFDPILQTGTREKNRLDLQSFLVKAFEKGVKNILAFTEDYRITGDSLQEIMFF
HVDSGKLFSVVDSLKGGHDVAGKDLKKSAEFFVGSGIDSACGRNVPDLELKEMEEMVRLG
TGYFLTTPVFDLDEFQKFMKRVEPFKVPVIAEVILLKSANTGHFINRYLKKGLVPGRIIQ
KLAKAPDKEKASIEIFTDIIKGLKDICHGVHLIPLGWEGKIPRFLDAAKL
>A0A1I0PXS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcaceae bacterium KH2T8|TrEMBL
MKITDLYKTQKKTLSFEIFPPKKDSELTNIDETLSILSGLHPDFISVTFGTGEVSDPDRT
ISLAKKIKDEYKVEPVVHLTCLHYDKNEIDHLADHLREEGIENILALRGDRNSKIPDKNE
FKHSTDLISYLKTKYDFCLLGACYPECHPESRDKVTDLLNLKSKVDSGAEVLLSQLFFDN
KTFYDFREKCRIADINTPVIPGIMPVINASQIKRMISLCNASFPLRFRKIIDRYEDNKEA
LFDAGLSYALTQIIDLLVNDTDGIHLYTMNNPIVARRICEGIKNIV
>A0A0D7BMT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cylindrobasidium torrendii FP15055 ss-10|TrEMBL
MKISQKIEQSNKADRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
ELTAEMVKICQGAIGVETCMHLTCTNMPAEKIDIALQSAKKSGCRNVLALRGDPPSGKDE
WEAVDGGFVHGIDLVNHIRKDHGDYFDIAIAGFPQHELLPAEERDFEFKCLKEKVDAGVG
FIFTQMFYDVDIFLAWAKRVRAAGITVPIVPGIAPIQTWNGFVKATSLAKIVIPQHFQDA
LEPHKNNDEKVREIGTKLVADMCRKILASDLGIRGLHFYTMNLEKGTKMLLQELNLVPRV
ETIKPLPWRQCLTPNRRTETIRPIFWANRAKSYVSRTENWDEYPNGRFGDSRSPAYGELD
GYGVSIKQSKEDAHTLWGEPASFDDIATLFAKFCRGELKALPWSDDAPAGETSVIADTLA
RMNELGFLTINSQPAVNGCRSDDKLHGWGPSNGYVYQKAYLEFFVKPELLNLLLSYIERD
SSITYYVINKRGDLRTNTHSDGPNAVTWGVFPGREIVQPTIVEAVSFMAWKDEAYELGMQ
WSKVYDAESGARKVIEELMDSCYLVNVVHNDFTDREAIFRPFMQAGEEYKKLLANGN
>A0A176L8H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. FXJ1.172|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPKGLAYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPKLSNAVF
PDALKERILTAKDDPTAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A6I1YTB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. RB17|TrEMBL
MLATGKTTYSFEFYAPKTPQGERNLWNALRRVEAVAPDFVSVTYGAGGSTRTTTVRETQQ
IVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVPHPRGL
AYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVDKCRAGADYAITQMFFHPE
SYLRLRDRVVAAGCETPVIPEVLPVTSVKMLQRVPKLSTALFPDALKERILTAKDDPAAV
RSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>A0A7S6M1H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chthonomonadaceae bacterium|TrEMBL
MKLSDALAQPVVCGDGAYGTLLAARGFPKQPYDLANLEAPELVADLHCLYFEAGAVLIET
NTFTANRFRFVDLRDDLYEINRAGARIAKAACGDGAVILGAIGPAGKPMYPLGSISSSEV
IESAREQARALEEGGVDAFLLESFLDLDELERVVEGVRQASNLPIIASKAFIEDGEAISG
GLPYQSAKRMAAMDVAAVGANCVVGPQRMLDLVRMMTEATSKPVLAYPTPGMPTLIKGRV
AYDTDPTYFAKACRRLAEEGAALIGGCCGTTPDHIRALSQELGRSPVQRAKRASVATRDY
ETKPLESTPRTEFGERIARGESTYSVELDVPRGLKLDRLMADVEAVRAAGAHTINISDGA
RARLRMNPTAVCHLIQSTTGAETTMHFSCRDRNLLAIQADLLGCHALGVRNVLAITGDPA
NIGDYPSATSVFDVDAVGLVRILGRLNEGIDLAGYGIGRKCGFTICVAFNPGSPRPEVEL
VRLQQKADAGAHAVYTQPVFDESLVEIALESCKKVGLPCLIGVMPLRNARHAEFMHNEVP
GILVPERLRAALADAPDDEAALDLGIGQALRLARLAKSGGAGVYLMPPANRITAAVKVLE
GIR
>A0A849VSM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium pellucidum|TrEMBL
MTKIAASIEVAARQAIESQDLPGLFPAGTRVYITDMGTDSVDTLTAAAKRVHDLGYKPVP
HFASRRLSTKAALETRIRRAAEEAGVTDILVIGGGLERQAGEFSSTMQVLETGFFDRYGI
NEMGVAGHPEGSPEFSEAVALQALRLKKNFGERTGAKLRVVTQFGFDAERFIRYAESLRE
HGIDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNALSLTALATSHSPEGVVGPIE
QHVIANPMSAIKQIHLFPFGGLKKTSEWLVERGSWNVNNAQYSSANAAAN
>A0A1Y3C828|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 3903|TrEMBL
MPQLSSFFQKNQFCILVEYLTSLNEIFPVKTAFAGYPAVMTLADRVHSDHDMAPLEASKR
YPDSVEKVLHFAGKGRDIQDFELFLQQAKAANINNLLLLTGDKLKEHHDGKDGAERSRYL
ESVNAVMAAKQHGGFLVGVAFNPFKYVEAERDALYLKLHKKIKAGADFIITQLGYDIDAL
KQVKAFLKRHHYAQKILACVMPLSLARANFMVKNKVAGIVITPHMLKVLADEKQAGLSER
VYLRCALQILMCKQFGFAGVDLSACHKPEEQMLLESYIEQYRHLGLDALESLWMSLWQIK
TGKEFIPELSSFSRQPSSSQIIKYYQLHLMHDALFDSKIAKGVGRFIFKAPFWERKAAAK
TLLKTEFISKHSIVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVEQTQVLKEKLILTVPIEVRGTSSWKNWYLATEV
>C6D4G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. (strain JDR-2)|TrEMBL
MKPDLRTKLKQRILTGDGAMGTYLYQMGFPVGVSYEELNMTRPDVIEGVHRRYYEAGARV
IETNTFSANLVKLSKYGLEPDMEAINRAGVRIAKAAAGEDAYVVGAVGSIRAGKLKDVRT
SEVSHAFERQLDALLVEGVDGILFETFYDFDEMRLALGLARKLTQLPVICQFAAQDVGRT
QDGTGLLDAFTLLKDEGADVVGFNCRSGPNGIMRAVESIGGPVELPLSIFPNAGIPDYVD
GKYKYSAGPDYFAETALQFADRGARIIGGCCGTTPEHIAAMAKALKDYKPQNGAAAVAIA
DSPEAEIIVIEAEPAEVVKNASGERADTPINSEPSLVDTVRVRHAVIVELDPPRDLDITK
FMAGAAAIKACGADAITMADNSLAVTRMSNLALAALVKERIGLRPLVHIACRDRNLIGTQ
SHLMGLDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMTKQLNDGIAFSGKPLK
QKAKFVVGAAFNPNVKHLDKAVQRLEKKIASGADYIMTQPVYDPVLIEKIAEATKHLPVP
VFIGIMPLASGRNAEYLHNEVPGIQLSDEVRKRMAGLEGAEGRAEGVRISRELLDTAIRH
FKGIYFMTPFMFYEMAAELTDYVWAKTGVQRR
>A0A4U2YTT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides jishulii|TrEMBL
MTPPRHGTSQEAVRQVAQRTVQRLEPLDVDALVLYDIDDESDRNPAERPFPYSATLDPAH
FAEQLEGWKKPVVIYRCVGKYTPDHLGEWLGAQDPERVMTVFVGASSRDKEVAVSLAEAQ
ELRRQLQPDLLLGGVAIPERHQLRGDEQARLLAKQSAGVSFFVSQVVYDVNAAKDLLSDY
HYACREAGVDPVPLVFTLSVCGSLKTLEFLEWLGVNVPRWVQNDLRHSSDTLQQSYDQCV
ATADELIAFADRLGLPIGFNVESVAIRKAEIEASVELAGHIRKRLEEYRDF
>A0A8J6XEZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Iningainema tapete BLCC-T55|TrEMBL
MLDTRNSIFTSFRTAALAGDFLITAEVAPPKGGNPEHMLQMAATLKGRVHAVNITDGSRA
VLRMCSLVASAILLQNGIEPICQVACRDRNRIGLQADLMGAHALGIHNILALTGDPVKAG
DHPDAKGVFDCEAVRLLQLIHKLNCGVDCNDKPLTDGALDLFVGAAIDPQCKSLSGLQSR
FERKLQAGAQFFQSQLITDFDLLEKFMDKIAVGCNKPILAGIFLLKSAKNAQFINRCVPG
VNIPDHIIDRLAQAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIAPILDMAGVA
PIHQVVVSV
>A0A2N3D2F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HGW-Alphaproteobacteria-16|TrEMBL
MAPPLFADVAGDIDVSFEFFPPKTEKMEETLWESIETLSPLDPRFVSVTYGAGGTTRERT
HNTVARIARETRIPAAAHLTCVEATQEEINAVAEEYWAAGVRHIVALRGDPPRAGEKFVS
PPGGYENAAALVAGLRKLHPFEISVAAYPECHPDSPDATHDLDNLKRKIDAGANRAITQF
FFEPETFLRFRDDAAAAGIDAEIVPGIMPVMSFAAVQKMSAMCGTDVPAWMERLFDGLDD
RPAARQLVSATLAAELCRKLYAGGVRQFHFYTLNRAELSYAICHLLGVRPRLGAEAAAA
>A0A0F5IPF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides gordonii MS-1 = DSM 23371|TrEMBL
MKVIDLINGSKTTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQNTEMYHEHATDLQEQVNNFNKGIAVDGSTFEANETPFSYGMACYPE
KHEEAPNMDSDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVDRCRAEGITVPIIPGIKPV
VFKNQLTVLPKIFRSDIPEPFATELRKCKNDDEVKAVGVEWCVQQCKDLIAHGVPSLHFY
TMMATDSVYKVAKEIY
>A0A0Q4QY32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf242|TrEMBL
MTNISIPQLAEARRALEEPLFADLAGDVGLSFEFFPPKSEKMETQLWEAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLRKLHPFEISVAAYPECHPESGGHDADIDNL
KRKIDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFAGLCGA
EIPAWMDRLFEGLDDHPSARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPVDKVAAA
>A0A327NYE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus yeomjeoni|TrEMBL
MKITEHLGNAKDTLFSFEILPPLKGQSLRELLEGIAPLMDFKPPFVDVTYHREEFIYKKH
PNGLLERVSTKKRPGTVGICAAIMNRFKVDAVPHLLCGGFTREETENALIDLNFIGVENV
LALRGDAPKSSGKFIPEPEGHSYACELVEQIVRMNEGRYLHEETEIGFQTDFCVGVAGYP
EKHFEAPSLKFDLKRLKEKVEKGAEYIVTQMFFDNAKYFEFVDQVRAAGITVPIIPGIKP
ITTIGQITMLPRTFFLDLPDPLMDELEKCKTNTEVKAVGIEWSIQQCKELVKKQVPSLHF
YTMSKADTTYKIAKEIF
>A0A4R2DCA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. SMB37|TrEMBL
MRVRWTGDSSWSNASSVARRVARHRHQAYPAPFVVAGGRLLVGAPYAGRVVVDFRGTSES
AVTGGAERVQQDGDSRTPSIVDRLGDPRGRRIPFSVEFSPPRDADAEARLWRAVRVFERL
GPAFVSMTYGAGGSTRDRTVRVTGELAEATTLLPVAHLTAVGHSIDELRAMVGAYADRGI
TNILALRGDPPGNPLGEWEQHPGGLAHADELVRLVRDLGDFHVGVASFPEGHHRSPDLDH
DTRFMVNKLRAGAEYSITQMFFDVEHYLRLRDRVAAFDAEQAAKPIIPEIMPITSLRSAR
RSLELSGSKLPAALEERLVRAAGGGPEENRAAVREVGIDVATEMCERLISEGAPCLHFIT
LNFARATSEVLTRLGIEMPAPAAQPA
>A0A1E5RUU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hanseniaspora uvarum|TrEMBL
MSNILNISNLYSKKFSINGSKPSISLEFFPPKTKMGLDNLIKRIERLTIAVQPIFITITY
SQLNNKKTLDLLEMIIKNNTDVFKNVNICCHLTCTNSSYQIINETLDKCLELGIKNILAL
RGDPVENDSGNENTYFRYAVDLVKYIKKRHGDDFCIGVAAYPEGHYNNEYNSKTNSYTSN
QSYREDLVYLKEKLQAGATFIITQLFYNVENFLQFYNEYKLIIPDYKKYLMIPGIMPINN
FMIFNRATKLAHVDIPKDIIDRFPLDIRNDDDQVRNIGVNIMVEIIERIHKETNQEVNVF
HFYTLNLEKSIAQIISKSTLLSQILEDSDSEESESSYEDAVYSSDDQAEEINEKTPKNFD
TTIXHLDSNTLLNKPKHTSEDIKLALGKDSDMEEDEDIIFDSDSDDHQDEPVSIKSFKEL
SIDAGTEKEIAPSSEHYSTKVQQYNKKIINPPKRKRTRSSQSSMNSGLLSSTLNKSLRKP
IKQHKKLFKEISKGTNPQLGKTILWDEFTNGRFGDSRSPAFGEMDGYGPTLKVASHKAIE
YWGNPTNIMNLSEVFEQYLLNSIPVLPWCDLVGITPETGLIQEQLLELINDKQILTTSSQ
PSCNGISSDDKIFGWGPSNGKVYQKAFVEFFISKTKWKLLKEKLDKNEKFGYYCGNAGHF
DTSFKNNQDSGSSCVVTWGVFPNSEVQQTTILEEESFKAWVEEAFQLWKEWAKIFPRNSQ
PQNFINKCFDDFLLVEVVYHDYSDFDGLWDFLLEDDESELHMD
>A0A2M7P574|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desantisbacteria bacterium CG_4_10_14_3_um_filter_40_18|TrEMBL
MSKQFKDVLASGEFVITSEIGPPKGTNIEKMLHHIEILKDKVHGMNVTDNQSSVMRLSSV
AVCHIITDHGGEPILQMTCRDRNRMALQSDLLSAYVLGVRNVLCLTGDHISLGDHKGAKQ
VFDLDSVQLIAAVKSLEAGQDIGGNKLDGGVEFCVGATATPEADNMDSQFLKFRKKIKTG
AGFFQTQAVYDMVKLKAFMEYARQSDVKILAGILVLVSAGMARYLNANVAGVTVPQELID
EMAGAEKGKALQKGMEIAARQIKQIKDEKICDGVHIMAIGKEEVVPEILSMSGV
>F7KQ87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 5_1_57FAA|TrEMBL
MKIRDILKDNSPHVSFEVFPPKTDAGYEGVRAATEKIAALRPSFISVTYGAGGGTSRNTV
RIASQIKNDLGVTSLAHLTCVSSTKDEVHGVIGQLKEQGIENILALRGDIPADGEFPLPN
HYRYACELVEDIKSQGDFCIGAACYPEGHVEAAHKKDDIMNLKHKVDCGVDFLTTQMFFD
NNILYNFLYRIREKGITVPVLPGIMPVTSAKQMKRICDLSGTVLPERFRAILDRFGEDPD
AMKQAGIIYATDQIIDLIANGLNHIHIYSMNKPEVAEAIIGNLSTIIKV
>A0A2T9Z4F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Furculomyces boomerangus|TrEMBL
MKIIDKINKAEQEGRPYWSFEYFPPKTPQGVLNLYERIERMGKLNPIFIDITWRWGGKSK
NLTQELCINSQTVYGLDANMHMTCTGTNINQVNEALKTSKRNNLQNILALRGDLISNIDT
KLISKDISELTTSDYNEIMMKTNEFQISSQLVKYIRDEFGDYFCISVAGYPEGCTCPNDT
DKDILVLKEKADAGADFVISQLFYDVGKYMQWIDKCKKSGINIPIIPGIMPIQNYNGFTK
MSDLCNISIPDEIWTSLASCKEDDLAVKDFGIKYAIKMIKQLSSYGIKGFHFYTLNLERS
TKLVLEGLQFVSVVAQPDISKELNLTKIQMFNRQEKQLPWPSTQNGKRSGENVRPIFWHN
NASTYIERTNSWDEFPNGRWGNSNSPAFGEIIYGKYWRYSNTKSIELWGLPTTISDIQEL
FVKYCEGELTDLPWSDSPLQLESNEIKDQLTKLNRLGYLTINSQPSCNGVSSTNLVHGWG
PKNGFVYKKAYIEFFIHPEKLQKLIKKLDEYNIENQESPTITYLAVSKHSDNLLTNFGKL
QPNAVTWGVFPGCEIIQPTIVDPNAFIAWKEEAFEYWNLWSKVYSGTYPASHNLIQNIMN
DWYLMNMVDNDYTRSSNFMYDLMSSL
>A0A1G6KYS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. CF095|TrEMBL
MKADLRKVMQERVLVGDGAMGTYLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
FETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGDTGYVLGAVGSIRGGKRTNVST
SELKRFYQQQISALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGIPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFAELGARIIGGCCGTTPDHITAMKEALADYIPSPILEPDPSE
SKPRIVLHEHVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKYLEKAVQRLEKKIASGADYIMTQPIYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATAHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A1B9G368|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kwoniella bestiolae CBS 10118|TrEMBL
MKITEKLQKAEKEGRTFWSFEFFPPRTAQGLQNLYDRIERMRNLGPEFIDITWGAGGKNA
DLTSSLVQVCQETIGIETCMHLCCTEMPKEKVEWALAQAKQHGCQNILALRGDPVAGTSK
WEPTPGGFNNAVDLVKHIHKHYPGDFCVAVAGFPQGHPETPEGADASKQEIQWLKEKVDA
GAEFIFTQLFYDVNIFFDWVKRVRAAGISVPIVPGIMPIQNWEKFEKWVARENIVVPQHF
YDALGPVKGDDEKVRQVGTKLVAQMCKEILANKEAGIKGLHIYTLNLEKGARMLLQELGL
EGRREQIAPLPWRPSLTPHRRAESIRPIFWANRVQSYLSRTDDWDEFPNGRWGDSRSPAY
GDLDGYPVSININANDAQNLWGHPTTFSEICDLFARFCRGDLSKLPWSSQPPASETSVID
EQLAKMNELGYLTINSQPAVDGVPSDDKVHGWGPTGGYVYQKAYLEFFVSPELLNPLIRR
IERDPRITYYAVNKQGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWANLYPPSSPSRELIESTMNTSYLVNIVANDFRDGMSIFEPFLLDQSASKVSKVVE
SAQQTVNGVLNGVVESVKNAVGLDGHAIANGNGIAVNGH
>A0A2M8MYY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodobacter sp. MZDSW-24AT|TrEMBL
MATPRISFEFFPPQTLDASFRLWETVQALAPMQPEFVSVTYGAGGTTRKLTHEAVTAIGK
NYGLNVAAHLTCVDATRAETLEIAAAYAEAGVTEIVALRGDAPKGAERFTAHPEGFASSV
ELIEALAATGKFTLRVGAYPEPHPDAADTLADVRWLKRKIDAGASSAITQFFFDAETFFR
FRDLCVKEGITAPIIPGILPITSWAGAKKFAQRCGSAVPARLDEAFTTAARDGREELYAL
AHCTQLCDNLLQGGVEDLHFYTLNRPHLTREVVRALGIQPEVVLEKVA
>A0A432RHZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcus sp|TrEMBL
MEPKNQYEKEYSFEFFPPRSAEAEELLVNTSDMLAALNPLFFSVTFGADGTSRDKTCETV
MNLKVRTGIESAPHISCIGSTRENIRGIIEDYRIQGIRRIVCLRGDMPSGMMDVGEFRYA
NELVEFIRQETGSYFHIEVAAYPEMHPQAPNIEADFQNFKRKIDAGANGAITQYFYNADA
YFRFRDACDKSGIDVPITPGIMPIGNFFQISRFSEACGAEIPRWMRKRFEYFGDDRESVH
SLSVELISGLCQRLLDNDVPGLHFYTMNRSHLVRRIWDNLDLK
>E4MC86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alistipes sp. HGB5|TrEMBL
MNVLDIINTAIAEHRTRFAFELLPPLKGDGMGGVFAAIDRLIGFDPAYINVTFHREGIKQ
SVRPDGGIDWHVVRRRPGTVGISAAIQKKYGVEVVPHLICGGQSKYDIEDALIDLDFLGL
HNVLALRGDKSQNEKFFMPHPQGHSHAVDLVRQIAAMNRGEFVDGEVEECHHSKFSIGVA
GYPEGHEESPSPEADIAALKAKIDAGAGYIVTQLFYDNARFFDFVRRCREAGIAVPIIPG
IKPLSTLRHLTLLPQTFGCRIPEELEREVLRHREDPKAIREVGTEWAVAQSRELKQAGVP
VLHYYPMGKADNIIKIAKAIF
>A0A430UIV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus|TrEMBL
MKIRDLLKAQEGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRERS
VLWAKRILDLGLNALAHLTVAGQSQEEVAGVLDRFVEAGVENILALRGDPPQGERVFRPH
PQGFRYAMELVAFIRSRYGEGVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRMGIEIPILPGIMPITSYPQFRRFTEVCGASIPGPLLSKLERHQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNRSPATRRVLERLGFKPA
>A0A5E9MX14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. tomato|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEDGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A2S5QQZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacter sp|TrEMBL
MQIQKTHPQLFSFEFYPPKTEEGAASLHAVRSQLAKLNPDFFSVTFGAGGSTRDKTFDTV
IDIQAKGIAAAPHLSCVASTKANIRAILKDYLDHGISKIVALRGDLPSGMMSAGEFRYAN
ELVEFIRQETGGHFQIHVAAYPEIHPQAANGNDDFKNFKRKVEAGADAAITQYFYNAEAY
FYFVDRCAKNGVDIPIVPGIMPITQYTQLFRFSEMCGADIPRWMRKRLEGYGDDRAAIQA
FGLELVTNLCQRLLDNGAPGLHFYTMNQAAPTVAILENLKL
>A0A0B7IJU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga canimorsus|TrEMBL
MKITEHIAKAKGQTLFSFEIVPPKKGNNIEELYQNIEPLIEFKPPFIDVTTSREEYFYKE
HPNGLLEKKITRMRPGTVGICSAIKYKYGIDTVPHVLCGGFTKEETEYLLVDCFYLGINN
VMALRGDAMKEERYFQPTKNGHTYAAQLVKQIKDLNKGKYLHDVIETDYGADFCIGVAGY
PEKHLEAPSLSFDLARLKEKVDAGADYIVTQMFFDNQKYFDFVERVRLAGIDVPIIPGIK
PITNKRHINLLPQVFKLDLPEILVTELEKCKTNKEVKQVGIEWAIEQSKELKNYGVPTLH
YYSMGKSDGIVDIVSKVF
>A0A1I1GAT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. CRIB-10|TrEMBL
MNAFRPSRHGSRRPRVSFEFFPPKNEEMEVNLWDSVRRLEPLGPAFVSVTYGAGGSTRER
THNTVKRMIDETGLKPAAHLTCVSASCAEVDDVIRSYWAAGVRHIVALRGDPAGGLGTTY
EPHPEGYHQTSDLVEGIRRIGEFEVTVSAYPEKHPEAASLDADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRSRGIEIPILPGIVPVQNFKQTAGFARKTGASVPQWLADRFEGL
EDDPATRRLVAAAVCAEQVLDLIDRGVSDLHFYTMNKADLVYAICHLVGLKPEKTQAQQV
AAE
>E6LZT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobiluncus curtisii ATCC 51333|TrEMBL
MTIKDLYAAPRPAVSSLPESGATSRRTGSGRDLRVSYELYPPRNSRLTSQAWAGIDRLLD
SRPDYVSVTFGTSGTTPDASQSVLWHALKRSGRPVLAHLTCLGKTRTKLVGIIQDMMDLG
VRDFLALRGDEAPDSASGAAEPNEFDRAFQLVQLIREVSADYLGDAHAVSIAVAAYPAGS
IQTRTDAVQALVQKQAAGADFAITQVFYQARDYAELVQSATYQGVTIPIVPGIIPFTDMH
RLQRLEGLTGVPVPERIKSIANISDPAERILESLGATLNFVNDLIEATAPGIHFYTFNRP
RPVLDLVEHLRSRGFTHVDQEDSQDLLGLMNATMHRISP
>A0A4J2FHW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCDNIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A7S8DSG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium pseudograminearum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDAEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSVEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFNSIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLERLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAVHPEWEATGLEAGGRAEAVNTRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWDYPKTRQDINDLFVKHIQGELSAIPWSE
EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PANEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGSTEASPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNLIHHDY
VNRDALWEVLSS
>A0A6N8T9I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella zoogloeoides|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTTELNPPDSANPEDVYARAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTTPPKVFLGA
AINPFAPPHDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGV
GPMASAKTAKWIRSNVPGIHIPDAVIKRLEGAEDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREPNPVDQLIAERIEAARNGQEQDQQQMAGQAA
QQPH
>A0A5K0WB82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nymphaea colorata|TrEMBL
IPDEIKAALEPIKDNEEAVRAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILM
>A0A7M2WQ02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus haemolyticus|TrEMBL
MSRLLKQLQNNVLVADGAMGTILYSEGLDTCPEAYNLTHPEKVESIHRSYIEAGADIIQT
NTYGANFEKLKRFGLEHKVKDIHKAAVAIAKRAAQPDTFILGTVGGFRSLQQEELPLSTI
QYHAENQIDTLVEEGVDGLLFETYYDLEELTNIVTTTRRKYDIPIIAQLTASNTNYLVDG
TEINQALQQLVACGANVVGLNCHHGPHHMQRSFSHIALPENAYLSCYPNASLLDIENSEF
KYSDNAQYFGDVAQELINEGVRLIGGCCGTTPQHIAYIKSSVKDLKPVTNKKVIPINRQT
NRAVTRTYKHNLTTKVKNGPTVIVELDTPKHLDTDLFFENIGKLDEAKVDAVTLADNSLA
TVRVSNIAAASIIRQRYDIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMNYFITQPVYSKAKIKEVYEATKHLNVPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLSQFKAVKDDKEKTKALSLRLSKELIDTVHEYFNGLYIITPFQRVDYSLELAAY
SKAITQNKEAIS
>A0A7L1NIE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhinopomastus cyanomelas|TrEMBL
MVNETQHTCSTSSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITMHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLKVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGIVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKRELEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEITTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A4H9U3Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSCQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIELIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNEHFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A259D9N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. 24-46-87|TrEMBL
MELSVEFFPPKTPEGESKLHLVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVRDMLKQYQALGVKRIIALRGDLPSGMGQYGEFHHANELVEFIR
AETGDWFHIDVAAYPETHPQAKSPATDVDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YDLGVTEPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDTASIRAFGEEVVT
DLCDQLLTAGAPGLHFYS
>A0A116LT86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELQIPTIAHLPAAYLTKEKVQSILHSLNEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARAIHQAIHSLFKHYS
>A0A258T427|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp. 28-63-22|TrEMBL
DVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIRSFGLDVVTDLCDQ
LITAGVPGIHFYTMNQAGATGEIMARLQQRR
>A0A495RM17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. AG790|TrEMBL
MMSHEPRVDAPAVARAASRRVPFSFEIYPPRTPEQLPALYETIRVLAAAGPRFISVTFGA
GGSTTDRSLTVLTHILRETTVPPVAHVTCVGSSYAEATTVIREFLDAGITRFLALRGDPP
VGVGEDDIVFGDLESAAQLVQLIGRVQAERSPYREREIPGLPGAVQVTDGDRVQIAVAAF
PNGHPRSRHRYEDIDALLAKQAAGATSALTQLFFHADEYLDFVERARAAGVVIPIVPGIM
PITSPGRLRRVLELTGDARPDALAAALESAPDAAAQRAVGLAHAADLARSVVAGGADGIH
LYAFNNHDTVLGVLRAAELIPEASP
>A0A116L8V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIHALNEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VHNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIINGLSPKEDFKYATD
LVSFIKEEAPQFDIIGACYPEGHPESPNAVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCILADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A8D9JUJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Portiera aleyrodidarum|TrEMBL
MNKNELEISFEFFPPNNNFKKKELIKLIKKLYKKINIDFCSITFGAGGSNKENTLDIIKS
IKKSNIECVPHLSCISSTKKEIINIINIYKKLGIKKILALRGDLNNYILTNNYFLNSINF
IKFIKKNFYNKFEIIVSAYPEMHPNTITLKKEILFFIKKFLFGADKAITQYFYDPDSYFY
FFEKVINFGINKPIIPGIMPITNVNKLITFSKKCGANIPKWISKSLENCKNKKDVEIIGK
EIVIKLCEILIKGGAPGLHFYTLNNVEPTLNILYELIT
>A0A1V5N3V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium ADurb.Bin401|TrEMBL
MQTPAKKRLSKALKNRDGFAIVAELVGGPNFSFAPIQKFLTAFNAGGGKDIPAGFNFVGI
TNPQSPGGVANIEPSDVHRFLVSKNLLGDLDFIPHISCKDLNADALTSLLAAHRAAGVES
VLALTGDKPAVSKGVFELESIGLLDKISRINNDAYLSAKPENLAAAKLFYAGAAVSPFKY
NEESQMQQYFKMEKKVARGAKFLITQVGWDWKKSVELMRYLKENNINVPVLGNVYLLSTI
TPAPRLMHDIKLPGCFVSDELLAKVYSESLNEHIERAAQQIAMYKSIGAAGADVGGVHDY
EMFIKILKRAAEIGSDWEKYKDNLCWPARRPFYLYDDAGNKTRLSDYPKTNAHRFFNFMH
WSILDPEHKGFHAFKKVMKFFGVDKNKGFFYKSFFMLEKPMKYCLFDCEECGDCYLPENF
GLCTIGGCEKGMDNAPCGDSTADGKCGNNLDRICIGDRIYKAAGSEKGGIEKLRKTINKP
RIPALEHSASIPNYLFGRDHTMKNAIFNIGEAIHASIPKTGMVMKQLLELGDDCFSKDSP
ELQYILALIESQAADGADYIAVNIDQFGETDPALAVKLMKEYVKLVRKFGRGVPVCVDSS
DDNVLIAGLKEWYDTSEKVQPPLVNSIKVYTMDNMMPLKKHYDFKFIGLLISEAKAATDT
VDDLYNLAKTLYDAAMKHGFKAEEIFFDSTVFPLAIDMPMQPGVPGYTYRTFNTIKRIKT
DPLLKNCHFSLGVTNSVRDLPARKIGVTRAYVEVAMRYGLDAGIVNAAHHLGNSPADPDL
VKLVEAYADLDGSSEKLNVAMQLMGDFCSKNRKPSA
>A0A383RNP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas reidholzensis|TrEMBL
MSLLKEALHEHRFVCVMEFVPKPSADRFAAIEAIMARTQLCGWPLTVAIGDRVGSPLDMS
PLDAFTSFDTPVPALLHFSGKARERQDLLTQLQHMDAAGLDQLLILTGDRLPGHEPGQRP
VRYLESVAALQIARQARPNWLLGAALNPFKYVEEEGGAQYFKAEKKLTAGADFMTLQLGY
DDRKHHEALQWMRRQRSPKPLIACLMALTHGRAKMLEHVAGAVVTPSMREILAAELEVSK
AFAQARSVERLALQIIGLKLMGYAGVHLSGIHDLAQLHALEQALETWQPQIDTLEQWAPA
WAASWQMPGLPAVAFNPPGANWRLGESHVSASPREKARYHLLSGFHALLFDRRNWVSRAF
GWAVTRPLWLSPGAARVLHGLERSIKRPLVGCDTCGSCRLQDTLYICPETCPKGLANGPC
GGTSLNRCEFGDRECVHSVKYRTAKSVGQTAVLTERLIPCVEVESRHRSSWPGWFEVGQA
VGANMSERGVGLRKETEAVPAVPGKAPRKRNDALAELDS
>A0A1Z4RYN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. NIES-4103|TrEMBL
MDNNYSHTYLNTFRRAALAGEFLITAEVAPPKGGNPEHMLEMAATLKGRVHAVNITDGSR
AVLRMSSLIASVILLQNGIEPICQVACRDRNRIGLQADLMGAHALGVRNILALTGDPVKA
GDHPDAKGVFDLEAVRLLQLIRKMNQGFDCNDKPLTDGALDLFVGAAVDPQCASWSGLQS
RFERKIEAGAQFFQSQLITDFERLEKFMDKIAAGYNKPVLAGIFLLKSAKNAQFINKCVP
GVNIPQHIIDRLAKAKNPLEEGMKIAAEQVQIARQLCHGVHMMAVKREDLIAPILDLAGV
APVDLVLAK
>A0A1G4PH14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcaceae bacterium YRB3002|TrEMBL
MKITDILNRGEMSLSFEVFPPKKETSFENVMNAAGQIAELNPSFMSVTYGAGGGTSDYTL
KLSSEIEHKYGVPILAHLTCVSSDRETVRERILELKNAGISNIMALRGDIPADMMDSDRS
GWDYHYAVELIREIKSIYPECCIGAACYPEIHPESRNQRDDLLHLKEKVDAGVDFLTTQM
VFDNNLFFNFLYKIRDMGVTVPVLPGIMPITKANQVERAIKLSGSYMPVRFRTIVDRFGP
DDDAMTQAGIIYATDQIIDLYANGITNVHVYSMNKPEVAAGIKNSLSSILGREFA
>A0A5M4FIG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium ginsengisoli|TrEMBL
MPSPDQSLVDAIRGPSPSYSFEFFPPKDDEGEAVLWQTIADLEAFEPTFVSVTYGAGGTS
QERTVRITARIAEQTRMRPVGHLTLVAQTKGEIESVLKQYAAAGVDNVLALRGDPKGGPR
APWEPHPDGMDHAIDLVGLAKDLGGFCIGVAAFPEGHPDAASIDHDAQVLVDKAEAGAEY
AITQLFFRASDYFALVDRVRAKGCDIPIVPGIMPILNFAQVARMAELSGAELPREVLDQV
EPIQDDKAAVRSKGIELATQLCRDLLAGGAPGLHFITLNRSKATREIFEALRADGLV
>A0A5C8LYB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rheinheimera tangshanensis|TrEMBL
MSFVSAQYLESMNRNLQDVAGKVNVSFEFFPPKTEQMENTLWQSIERLAPLAPSFVSVTY
GANSGERDRTHDIIKSIKQRTGLIAAPHLTCVDASRAELERIAKDYWDNGIRHIVALRGD
LPPGNKEKPALYAADLVEILRSVADFDISVAAYPEVHPESPNAQFDLLNLKRKVDAGASR
AITQFFFDPEKYLRYRDRCAAIGIDVEIVPGILPVTNFQQLQKFATMTNVAIPSWMNKAY
EGLEQDATTRNLVAANIAMEMVKVLSREGVNHFHFYTLNRSELTYAICHLLGVRPQSAIA
>A0A1G3BXR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium RIFCSPLOWO2_12_FULL_39_13|TrEMBL
MTEHRMNLQSGSNLEILLRSGQFAVTAELGPPRGADRSAIEKKCEILKGYGDAFNITDCQ
TAVVRMSSIAAGRIVLDAGLEPIIQMTCRDRNRIAIQSDLLGAAALGAKNLLCLTGDHQK
FGDHPMAKGVFDIDSIQLIQIVKILRDEKKFQSGQELKTSEPRFFIGAAENPFADPFNFR
AIRLAKKITAGADFIQTQIIYNVKKFNDWMKMVTDMGLHEKAFILAGVAPLKSAGMAKHM
KHNVPGMDVPDEVMNRMNAASAVKKGKEEGIKICLEVIEQVRAIEGVAGVHIMAVEWEDA
VPEIVKQAKLHPRPAI
>A0A5P9HXL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp. THAF9|TrEMBL
MTGTSDTPSISFELFPPKTEAGVTRLRDTVAQLSAADPEYFSVTYGAGGTTRDRTARIVE
MVANRTGLPVAHHFTCVGASRAEIDRQAEAFWETGMHRIVALRGDLPEGQSLPDDGYNDA
AELVTALRRKGDFDISVAAYPEVHPEARDAAADMDHLKRKIDNGAARAITQYAFDTDTVL
RFVDRARAAGIDAPIVAGIMPVANFEGLKRFSAGCGASVPDWMGQMFDGLDEAPETRAMV
ATGVAAEQCRRLMEAGITDFHFYTLNQPKVTLAVCRTLGLTPDIMAENAA
>A0A7Y1TV14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Woeseiaceae bacterium|TrEMBL
MRFDDEPLIPGESLPIRPGHVSPGRLERVLRAGAFAITAEIAPPDSADPNEVYERAALFD
GFVDAMNATDGSGAHCHMSSVGMCSLLTRRGYAMVMQVSARDRNRIAIQGDVLGAAAMGV
FNILCLTGDSVEVGDHPEAKPVFDLDCMSMLEMVRIMRDEKRFLSGRKLTEPPRVFLGAA
ANPFGPPLDYRPHRLAKKIAAGAQFIQTQYCFDIDVFKQYMAAIRDQGLHEKVFILAGAG
PLASAKSAEWIRANVPGVHIPDSIIKRLRGAEKQGEEGIRICVELIQQLADIDGVSGAHI
MAFRQEHRVAEIVERSGVLGDRQPWTPTSAAVTH
>A0A268B4S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. 7523-1|TrEMBL
MKADLRSVLQERVLIGDGAMGTYLYQMGFPVGISYEELNLVSPEVVADVHRRYLEAGTEI
FETNTYSANYDKLSKFGLESKVTEVNRAGARIAKEVAGSNGYVLGAVGSIRGGKRTNVST
SELKRFYEQQIFALFEEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDIGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGVPMSVYPNAGAADYVD
GQFRYGATPEYFGQTAVQFADLGARIIGGCCGTTPDHIGAIAQALSEYTPAPIVLPDPTE
AKPRIVLHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVAFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDPQLIVAMHEATKHLEVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATDHFKGIYLMTPFMFY
GMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A7U3Q191|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epichloe festucae (strain Fl1)|TrEMBL
MHIKDMLLEAEKDGQPSFSFEYFPPKTAQGVQNLYERIDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMAMEKVNDALQRAYKAGCTNILALRGDPPRAQEK
WTATEGGFQYARDLVKHIRATYGEHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVNMGASF
IVTQMFYDAENFIRWVGKVRERGIAIPILPGIMPIATYASFMRRAKHMQCKVPEAWMAAL
EPVKNDDVAVREIGMTLVAEMCRKLLANGIHHLHFYTMNLAQATRMVLEELHWAPCAERP
LQHALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTTVQEIADIFVRYLNQEIDCLPWSEAPLTSEADAIKDRLIA
LNKRGLLTINSQPAVDGVKSSDSVHGWGPSNGYVYQKAYLELLVPPSIFTQMVKRIESKP
TLTYYAVTKDGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
AHCFESNTASRILLDQVMNEWYLINVVNNDFHENETIFDLFEGLEVKGLDEPVSTS
>A0A2S6UKM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha3_Bin4|TrEMBL
MPFAVTTPAPAEIEKSGSNLERLLAAGHFAVTGELGPPKSIDTDFVEKKICLLKGYVDAA
NVTDNQTGFVRLSSIGTGILLAQAGLEPVIQMTCRDRNRLAIQSDLMGAYVHGIQNVLCL
SGDHQSFGNHPGAKNVHDIDSMQLIRMVQEMRDKSVFQCGDEIKGGGPRLFIGTAASPFA
SPVGMRPFRLAKKVVAGADFAQTQMIFDMKRFREYMKKVVDMGLHEKIFILAGVGPLKST
PMARFLNEKVPGIEVPDECLKRMEGAVKGIDTDNKDELRDAWRAEGIKMCIEHIQEAREI
EGVAGVHIMAIQWEAAIKTIVDGCGLYPRPSVSV
>A0A0D9PBB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium anisopliae BRIP 53293|TrEMBL
MHIKDMLAEAEKGGQPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLDKVNAALQKAYKAGCTNILALRGDPPRAQEK
WTAAEGGFHYARDLVKHIRATYGDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGKVRERGINIPILPGIMPIATYASFLRRAKHMQCKVPDHWMTAL
EPVKNDDVAVREIGKTLVAEMCRKLLANGIYHLHFYTMNLAQATRMLLEELTWAPCAERP
LQQALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTTVQDIASIFVKYLNREIESLPWSEAPLTGEANAIKDNLIQ
LNKRGLLTINSQPAVDGVKSSHPIHGWGPSNGYVYQKAYLELLVPASIFTEMVKRVEDKP
TLTYYAVTKDGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGTDW
AHCFESETPSRVLLDQIMNEWYLVNVVNNDFHENQTIFDLFEGLEVKGLDTPVAV
>A0A3S5JL72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED182|TrEMBL
MFESTKFLFTAETTPQLSTDLGASAGLVDALLGLADAINVTDSPNCQTKLSSLLVAAEIR
RKGLDIILQLTGRDRNRIALESELLGALSVDINKVLCLSGDQPPSDGPKAVNEYNGSGLI
GLCATLSEGALTDGTXIKNPRPLFSGAADDLYXHQAXPEAMAGLLAKIDRGARFVQTQYC
FDLDIIKAYSDRLMAXGKTDEWKVIVGMGPLKSAXQADWMRKNLWGVHISDEIVERLEKS
DAPMRTGEDVCRELITQIMDLPGIDGVHLMGPSCERQSAEIIRSFR
>U2ULL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia sp. oral taxon 225 str. F0581|TrEMBL
MKIKDMFEQKEHLISFEIFPPNKNFSQEKLKEVTAELVECKPDFISVTYGAGGQTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEIHDYLQEAKSKNVKNILALRGDVPQGETEDIYN
KGDYKYASELISDLRKNSDFDDFSIGGAFYPETHYENNDLVDLFHLKNKVEAGTDFLTSQ
MFFDNDIFIKFKEKAEKLDIKVPLVAGIMPVTNAKQIKRIIELSKCSVPHTLDKLLEKYG
DNPESMKKAGIMYASEQIIELLAYGIKGIHIYTMNKPEIAKEIMKNIEFAR
>X1KIE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MKLTERFKQGKFVITCEVGPPKGIEIEKVIDELEPLRSKIDAFNVTDLQSSVLRVGSMAT
CRLLKEKDFEPIMQLTCRDRNRLGLQSDVLSAAVLGIENLLCLTGDHPQLGDHPEAMPVF
DLDSVQLLSAVKGLMNGKDMAGNDLEGRPPHFALGATVNPGADPLEPQIIKMEKKIEAGA
EFFQTQAVYEVDKFANFCEKVKHLK
>X1TKW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
WIPVLAGVIPLKSVGMARFMNKNVAGVFVPDELINKLAEAEDKVKTGIEIAANLIKELKG
ISQGVHIMAIGSEKKVPQILDAAGL
>A0A7Y9S1V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides daedukensis|TrEMBL
MNIESRRSIGALIREGKRSFSFEFFPPKDEAGEEQLWQAIRDLEPYRPTFVSVTYGAGGT
TRDTTVSITGRIARETSMVPMAHLTCVGHTVEEIQQVLTSLADSGVHNVLALRGDPPGGP
GTEWVSTHGGVDYASDLVRVIKEVADVSVGVAAFPEGHVDAATLDDDVAVLKAKQDAGAE
FAVTEMVLRSSDYFALVERAKAAGVDFPIIPGVMPILNINSMRRMVELSRREMPAEVVDR
LRPFEEDPAGLRAEGIRIATQMCEEMLAGGAPGLHFYTLNRSKATREIFEALSITA
>A0A0F9MDZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MNEKNNIDDNFKSGSNLEKLLKRGEFVVTSELGPPRGASREAVEKKAEILKGSADAFNIT
DCQTAMVRLSSIASGVILINMGMEPVIQMTCRDRNRIAIQSDILGAAALGMKNLLCLTGD
HQCFGDHPDAKGVFDIDSIQLLDIVRQMRDEKRFQSGEELKVEPRLFLGAAANPFADPFK
FRAIRLAKKIAAGTDFIQTQIIYNIKKFEEWMSIVRDMGLHKKVFILAGVTPIRSLGMAK
YMKNNVPGMDVPDEIIKRLEGAEKKKVEGINICLEIIERLRKIEGVAWIHIMAIEWEEIV
PEIVERAGLLPRPNL
>X1FK50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MIRKISDILKEKERTYSFELFPPKTEKGREKLPETAGTLKELEPDWFAVTYGAGGTTREL
TMDIVDELQKRLLVPTMHHFTCVGHSKA
>A0A847E6S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smithella sp|TrEMBL
MQENRFKEALLNPSVFPVTWELVPGRGAREAAQDKALDLARQAISNSHIYALTLTDNPGG
TPAMSADFMGSEIVRLGIEPLVHFTCKDKNRNAMESSLYALDRAGVRNLLVMSGDYPVSG
YQGRPAPVFDLDPIHVLQLISEMNKGLEYPGMKGTTRHQPADFFAGAVVSPFKATEAEQI
IQYSKLKKKIEAGAQFIVTQLGYDARKFHEVLLYMKQNGFSIPLIGNIYILPFGAAKMMN
RNDLPGSVVTDKLLADLDHEKNAPDKGQGARILRAARMYAILKGMGFSGVHIGGHNIKYE
QVDAIVEIGESLTSQWKDLVQYFDYPIEGGFYYYEKDPETGLNREAPVKLEDQLPDVKIG
CSYAFSRFFHRFMYKPGKNLYGFMKGLCGKIQGTIMEGPFHKMEHLTKAVLFDCRDCGDC
ALIDVAYLCPMSQCPKNQRNGACGGSYKGWCEVYPGKRPCVYVRAYARLKKYGEEGQLSG
EIVPPCNWDLYQTSSWINYYQGKDHTSQKFSNKPS
>A0A315SZB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CC120222-01a|TrEMBL
MSLLKAALREKHFVCVMEFVPKPSAERFAAMEAIMARGQLCGWPMTVAIGDRVGSPLDMS
PLDALASFNTPLPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGERP
VRYLESVAALLIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DASKHQEAMHWMQRQASPKPMLACLMSLTHGRATMLEHVAGVTVSPSMCDLLEAESKVSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGIHELKQLLALEERLEHWQAQIHSLEHWAPA
WADSWQMPGLPIVAFHPPQGNWRQGESTVSASAKEKVRYHLLHSAHSLLFSRTNWLSKAF
GWVVRQPLWVTKRGARVLHGLERAVKRPLIGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFETQPP
RQLSPQPAPRTQPES
>A0A0F9LDH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQVVRDQLAGVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTREEIAELLDLYKENGINRIVALRGDMPSGMGAAGEMRYAN
ELIAFIREHSGDHFNLEVAAYPEFHPQARSAEDDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKLGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDKESIRK
FGEEVITDMCERLLKAGAPGLHFYTLNQAEPSINIWKNLGISEREKIAF
>X1Q728|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MATSFKKALSSGKFIVTCEIQPPKGSDIESMLSRIDLLKDKVDALNATDNSSAVLRFPSL
GGSIFIREHGGEPILQMTCRDRNRLALQGDLLFAYSKEIRNILCMTGDYVTAGDHKEAKA
VFDLDSVQLIRTVRLMESGKDL
>A0A3M7EMG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MHITKKLAAAHAEGRPTYSFEYFPPKTAQGVQNLYDRMDRMHGLGPAFIDVTWGAGGRMS
SLTTEMVKVAQSAYGLETCMHLTCTDMEKEKIDGGLREAYQAGCTNILALRGDPPREKEK
WEQTEGTAFRYARDLIKYIKAQYGNHFDIGVAGYPEGCDAETDADGHIPFLKEKIDAGGS
FIVTQMNYDAEIFIEWAKKVRAAGVPESVPIIPGIMPIQTYDSFLRRANWTQCRIPPQWM
EALEPIKADDAAVREVGKKLVGDFCRKLLDSGVTMHLHFYTMNLEKSTYMVLEDLAVTPP
SDHHDPELKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVMRTQDWDEFPNGRWGDSRSPA
FGALDAYSIGLKGTNEQNRKLWGEPTTVQEVAELFVKYMSGKVETLPWSEQPISPESNVL
TNDLVNLNSRGLLTINSQPAVDGIKSSHPVYGWGPNNGYVYQKAYLEVLIPPSLITEIIR
RMDANPDITYYAVNNSGELKTNAPQDGGPNAVTWGVFPGKEIVQPTIVETISFLAWRDEF
YHLGSEWAKCYDEGSQSKNLIKEITESWYLVNIVDNDFRNMRGIFPLFDGLKVEGVEPVA
AVNGVAGVNGDVKGDVEKKEGTRKPEVNGVPDGNNAVNCADGAAVNGQVKN
>A0A2W6TBC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp|TrEMBL
MATPLLSAAEIARLKISFEFFPPKSPEMDGQLWDTVADLGGWEPDFVSVTYGAGGSTREP
TLVTVRKLIAETALRTASHLTCVGSSKDEVHRVVEELKAAGVQRFVALRGDPQEGPGSTY
RAHPEGYANAAELVKGLKALGDFDISVSAYPEKHPESESVAVDIDMLKRKADNGADRALT
QFFFDNDQFERYLTAVRAAGITIPVLPGIMPIQNLTQLKRFAGRCGTSIPAFLDERFAGT
EDDATRRFEVAADVAAEQIADLVRRGVSDFHLYTMNRAPLTNAVLSRLGLARKDAKPA
>A0A522XN66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rugosibacter sp|TrEMBL
MNLELSIEFFPPQTVEGIEKLREARERLAILKPAFFSVTYGAGGSTQERTLATVSEIAAA
GHVAAPHLSCIGATQASIRELLTLFRDRGIRRIVALRGDLPSGMADPGEFRYANELVAFI
RQETGDAFHIDVAAYPEWHPQAKTPRDDLLNFKRKVDAGANAAITQYFYNIDAFESFVAD
ARALGITAPIIPGIMPIASFSKLARFSDACGAEIPRWMRKQFESFGDDTASVQAFGLDVV
TDLCHQLINRGVPGLHFYSMNQSRLTLEICRRLGTG
>A0A1C2DYF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium hungaricum|TrEMBL
MNQFRLSRRPDIGDKIRVSFEFFPPKTDEMEARLWETVKRLEPLRPNFVSVTYGAGGSTR
ERTARTVRRILTETGVPAAAHLTCVGATREEVDAVIRDFSATGIKRFVALRGDPASGVGQ
AYTPHPGGYQNGAELVAGLKGIADFDISVAAYPEKHPESPDFATDIEMLKRKVDNGAKRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFRQVANFATRAGAHVPAWLAERFE
GLDNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRAHQPAAE
AAVPASHTATVAKAGPAAA
>A0A1C2DM91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas graminis|TrEMBL
MSQDRSYSFEFFPTKTDAGHEKLLATARTLASYNPSFFSCTYGAGGSTRDRTINTVLQLE
KEVHIPAAPHLSCVGDSKADLRSLLTQYREAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLKNFVRKANAGANSAITQYFFNADSYFH
FVERVQKLGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTASIQAFG
EHVITEMCERLLHGGAPGLHFYTLNQAEPSLAVWNNLKLSAW
>A0A1W0D6Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium haemolyticum|TrEMBL
MTAQSRTFSFEFFPPKTPEGIAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLATVLEI
RSEGHAAAPHLSCIGSTRENIGAILNEYRNNGIRHIVALRGDIPSGMVAAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLNNFVRKVHAGANSAMTQYFFNADAYFRF
VDEVQARGVNIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRQRMQAYYDDSASIRALGL
DVVTELCDRLLQHGAPGLHFYTLNQAGLVSTVWQRLGL
>A0A344UVC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidipropionibacterium virtanenii|TrEMBL
MLSSTRPAETIADLLTRAERPLTSFEFMPPRSEEDVYRLWRATDALVPLSPDFISVTYGA
NGSSRDRTLRCTRHMVASGLRTVGHLTAVSQSVAELEQAVRDYHDAGVDHILAIRGDMPG
GATEPWLARPDGLANATDLVRLVHRVNPDACVGVGAFPDCHPASGDLDLDARILADKAEA
GASYAITQLFFIPEHYTDLVARVRALGCDIPIIPGIMPITSFGQIRRFGELSGTDVPADL
VARLSEVAEDRAAVRAIGLEAAARLCCRLLDQGAPGLHYYTLNRSRATTELHAMVRDRRP
GMWDR
>A0A2D1KKS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loigolactobacillus coryniformis subsp. torquens DSM 20004 = KCTC 3535|TrEMBL
MSFKEALQQQVLIADGAMGTLLYSQYGVNSAFEGLNLTHGGDILKIHQAYIAAGADVIQT
NTYAANRIKLNRYGLADKTKAINEAAVSLAHTAQIAAEHPVYVLGTIGGIAGVTDTEIEP
LTAEEIDAGVQEQATCLLQTQAIDGLLLETYYDINELKRALKIVCALTDLPVVTNVTMYE
PGVLQDGTPLNTALQDLAALGADVVGANCRLGPYNMSRAFESVALPKTAALAIYPNAGLP
DVQDGKTVYDSPAEYFENYSDTFRRQGAHLIGGCCGTTPAHIKGLVAGLQSRQPVTTKKV
TLPAAEAVPTAADPRQHDFLQRVQHEKVALVELDPPKTFTTAKFFRGAQALSQAGAGAIT
LSDGPLANPTISNVALAAQLKYQYGITPLVHLTTRDHNLIGLQSEIMGLHTLGIANILVI
TGDPAKVGDLPGATSVYDLHSVELMQMIKKFNAGISPTGRNLQEKTNFAVGGAFNPNVRN
VERACKMITRKSAYGADFIITQPIFDVTKVHELRLALDEQGITTPIFVGVMPLLSFHNAN
FLHHEVPGIRLADDTLARMQQAEADGNEREVGLQIAKETIDAICADFNGVHINTPLRHHE
ISLELLNYVQAKNAVSV
>A0A6H0FZP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKSYPESIDKVLHFSGK
ARDIQDFERFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYLESVNAVMAAKQHGG
FRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEALKQVKSFLTKNNYSQ
QILACVMPLTLGRANFMVRHKVAGIVITPHMLKVLADEKQAGHTDRVYLRCALQILICKH
LGFAGIHLSACHKPEEQMLLESYIEQYRHLSLKALEELWNSLWQVTSGKEFSPEIARFSR
QPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALVVKVLIKTEVLSKHSLV
GCESCGQCRLGETLYICPETCPKGLANGPCGGTTLDRCEFGDRECIHSVKARLAKAVAQT
EILKEKLIPTVPLETRGTSSWKNWYLAT
>A0A7J8KD39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rousettus aegyptiacus|TrEMBL
MVNEPRGHGSLNPRLEGSSSESSKDSSRCSTPGLDPERHERLKEKMRRRMESGDKWFSLE
FFPPRTAQGAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLE
TILHMTCCRQSREEITGHLHKAKRLGLKNIMALRGDPIGDQWEDVEGGFCHAVDLVKHIR
SEFGDYFDICVAGYPTGHPDTGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKAC
SEIGITCPILPGIFPIQGYHSLRQLVKLSRLEVPQQMKDELLRVNRRGILTINSQPNVNG
LPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYEQRVNYHIVDVKGENITN
APELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEDESPSRMIIQ
YIHDNYFLVNLVDNDFPLDNCLWHVVEDTFELLSRPGSE
>A0A1A8ZLU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora auratinigra|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTAQGERLLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRHVIGRLASAGVRNVLAVR
GDPPGNPGGDWIRHPEGVLYAEELVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADEYLRLRDRVAAAGCDTPILAGVMPVTQLATIERSVQLSGAPF
PPALAERFARVADDPEAVRRLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWQHLR
ADARV
>A0A6I7PST8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHIQDIFKQRSTTVSFEFFPPKDDGAAESLFNAIAELEALRPSFVSVTYGAGGGTRQVTH
DLVLRIKKETALDPMPHLTCVCHTEAEIYDLLENYARAGVSNILALGGDTPRGMPDHDRS
RDAFRYASDLVRFIRQFKDRHAGGLIPDPRGFGVGVAGFPEGHPATPNRLHEMDHLKAKV
DEGADFIITQLFFDNRDFYDFRERCEIAGITVPIIAGVMPITSIGGMKRMAELALCSRFP
APLLRALDRCADDAGARRVGVHWATQQCMELLDHNVRGIHLYTLNRSKATREIYATLGVR
DSLALM
>A0A7C6XPL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp|TrEMBL
MSSTIVTPRLSASAPDNAPDRLPVGRRRLRRALSFEVIPPRSPAQAARMPRLLKFLDSLG
PDYLAVTSSATSNWLQGTADFIAEVTATTTLRPLAHLACTAGTEAELLGWIDHLLGVGVR
GFLAIRGDIPAGQTSLPAGHLPHADALVSLLRRIENDNVACLAAGRLGIGVAAYPSGHPE
STGPEEDLDVLAAKQRNGADFAITQLFFDPTAYSRLRRRAEHAGIIIPIIPGILPITDPR
RLHTMSRLSGLPVPDSLLARFDGISDPTSARRIGLDITAEHTAAILEHDADRLHFYTFND
QNTTEDLLTALEQKGISVSSFPPQPPPRRLPPSTDHATTKENHA
>A0A7D5RLW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclobacteriaceae bacterium|TrEMBL
MKVTEHLKRANGKTLFTIEILPPLKGENIRSLFNNIDPLMEFKPPFIDVTYHREEYVFKK
KEGGLLEKITTRKRPGTVGICAAIQNHYKVDTVPHIICGGFSKEETENALIDLNXLGVDN
VLVLQGDAIKTESKFIPEXDGFAYASELLEHVVNMNRGQYLDEELHEPSPTNFCIGVAGY
PEKHFNAPNLKTDLKYLKNKVDKGAEYIVTQMFFDNKXYFEFVDKCREAGITVPIIXGIK
PLTTKSQLTILPQIFHIDLPEELTEAAEKCKDNTAIKQVGIEWSVQQSKELIQKGAPTIH
FYSMGKSDPIYRIAKELF
>A0A8H7BEE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alternaria burnsii|TrEMBL
MERITDKIDALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCVGVAAYPEGHSDQSHPQHQDPQFDL
PSLIEKTKAGADFIMTQLFYDVEAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTTLSHAKLPSDMLARLDAVKSDDELVKQEGVKIMDEMVEHIKARPDTCRRGFHFYTLNL
EKAVSHIVEDTHLIPSTIDDNDDVIVETTPAINLEPPPNGFVPHRRRSSAVNSGPRNRVI
ISHSSAAKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKDDISKLFRRHIEGDLEAIPWSEQSLSP
ETLTISKQLLALNAKGWWTVASQPAVNGVKSTDPVFGWGPKNGYVFQKPFVEFFIPASEF
AALKPKLDAHEQVTYFAGNAAGEFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIFQEWQRIYPPRSASSTLLGALRRDYWLVNVIWGDFVQGEGLWEFLEQ
>A0A7J8KCZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rousettus aegyptiacus|TrEMBL
MKDVIEPIKDNDAAIRNYGIEQAVSLCQKLLASGLVPGLHFYTLNREMATTEVLKRLGMW
TEDPRRLLPWTVSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGE
LKDYYLFYLKSKSPREQLLKMWGEELASEESVFEVFACYLSGEPNQNGCKVTCLPWNDEP
LAAETSLMKEELLRVNRRGILTINSQPNVNGLPSSDPVVGWGPSGGYVFQKAYLEFFTSR
ETVEALLQVLKKYEQRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVS
FMFWKDEAFALWIEQWGKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWHVVEDT
FELLSRPGSE
>A0A7C5SJH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHFQDMFIKHPATFSFEFFPPRGNAGSDDLYLAINELVPLRPTFISVTYGAGGSTSDLTH
ELVLRIKREGRLDPMPHLTAVLHDRTRIRSMLEGYAACGISNVLALRGDPPRGMEISESL
DGDFRYAAELVSFIRSFNDEGVHPDPRGFGVAVAGFPEGHPQTPNRLLEMDYLKAKVDAG
ADCIITQMFFDNRDFYDFRHRCELAGINVPIIAGIMPILSINGMRRMAELAAGARFPAPL
LRAIRRTGGEPDAVRRMGIHWATEQARDLLDNDVDGIHFYTLNKSTATREIYRTLGVSDS
RGMVV
>I9F9P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei CL02T12C06|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKNGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNIEQDLYWLKKKVEAGADYVVTQMFYDNQKYVAFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAIKCKDDKEARALGIEWCVNQCRELIAYGVPGIHF
YTVGAVENVKEVAAAVY
>A0A3P1XHB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium OH2545_COT-014|TrEMBL
MTVSLSLEFFPPKTPEGAQKLRATRQQLYALKPEFCSVTFGAGGSTQDGTLAAVREILAE
GVPAAPHLSCIGQTRESIRQRLADYRAAGVRRIVALRGDLPSGYGGGGEFRYASDLVAFI
RAETGGHFHLEVAAYPEMHPQARSPAADLDAFATKVAAGADSAITQYFFNADAYFRFRDE
LAARGLHVPVVPGIMPITNSTQLLRFSDACGAEVPRWVRLRLESLGDDTASIRAFGLDVV
SALCQRLLQGGAPGLHLYTMNQSAAALALAQRLG
>R6MKG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:41|TrEMBL
MFIRDIFAQKKPVLSFEVFPPKKDSGLDNVISAVDELSKMPIDYMSVTYGAGGSNSKNTA
YIASHLKNNLSIPSLAHLTCVANSKDDIKVKLQEYKDLGIENILALRGDKPKDYDGEIFP
GYHYANELVEAIKDFGDFCVGGACYPECHPDSPSLDADIENLKVKVDAGVDFLVTQMFFD
NDEFYKFRDKLAKKGINKPITAGIMPLTNAGQIQRMAILSGGASMPSKFLRMISKYQDNP
EALKQAGIAYAVDQIIDLLSNDIDGIHLYTMNKPETAQKIVNVINNLFV
>A0A1T5M3I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ohtaekwangia koreensis|TrEMBL
MKVVDHLKNANGKTLFTIEILPPLKGENIKSLFNNIDPLMEFKPPFIDVTYHREEYVYRK
KDGGLLEKITTRKRPGTVGICAAIQNHYKVDTVPHIICGGFSKEETENALIDLHFLGVDN
VLLLQGDAIKSESKFVPEPDGHRYASDLLGQVVNMNMGVYLDDELTTAAPTNFCIGVAGY
PEKHFNAPNLKADLKYLKLKVEMGAQYIVTQMFFDNKKYFEFVDKCREAGIEVPIIPGIK
PLTGKGQLTVLPKTFHIDIPEELSDEAEKCKDNTALKEVGIQWCIQQSKELIQKGVPTLH
FYSMGKSDPIYRIAKELF
>A0A2T5AZD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycoplana dimorpha|TrEMBL
MTFGQNARRSDSLRLSFEFFPPRSEEGERQLGETIDALAAYAPEFVSVTYGAGGSTRQPT
LATLARIIRDTPLEAAAHLTCVGATRPEVNAVIEEFSAVGIRHFVALRGDPAGGVGAAYQ
PHPGGYANAAELVAGLRQIGEFEISVSAYPEKHPESRDVAADIDMLKRKVDAGATRALTQ
FFFDNDLYARYLERVRAAGITIPIVPGILPVHNLGQVQKFAGLCGATVPQWLAERLAPLD
ASPEERAAVAAEIAARQVEGLIGLGIDEFHFYTMNRSALVSAVLDQVGFRRRNQAAA
>A0A2V1NHW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. V2|TrEMBL
MTAPHSLFLGASLEMTGKDAPALEGAGLAPGTRVNITHLASEDLDTRVDAARAVGKHGLV
PVPHLSARRLRSPAELSETLAALRSAQAVESVFVVAGDPTTPHGPYPDALSVIRSGLLEE
HGVRHVGITAYPEGHPAIGTEALWSALEEKTSALREQNLAATVTTQFGFAVDPVLAWLEE
ARARGVDVPVRIGVPGPAGVRRLLAYARRFGVATSTGIARKYGFSLTQLMGTAGPDRFLR
ALAAGLVPEIHGEVALHFYTFGGLAATSAWLTGAAAAPLPPQSPRSPASRTTAG
>A0A368KBN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium salinisoli|TrEMBL
MSVFGLSRRPDIGQTTRVSFEFFPPKTEEMEKRLWETVTRLAPLKPEFVSVTYGAGGSTR
ERTLRTVARILKETDVTPAAHLTCVDATKEEVDTVVREFAALGIKRFVALRGDPAGGVGD
QYRPTPGGYLNGAELVAGLKAFADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPILPGILPIHNFKQVTNFCSRAGTHIPAWLAERFD
GLESDTQTHMLVSAAVAAEQVLDLVERGVQDFHFYTMNRADLAFAICHLIGIRPQKHGAE
SGLTKEASQDLAGAAA
>A0A1I3I0S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Albimonas pacifica|TrEMBL
MTDKTGRRLSISFEFFPPATPEGAMRLWRSVERLAPLAPDYVSVTYGAGGTTRDRTRNAI
KAILERARLQVAGHLTCVGATRAETLAEADGYRRLGARRIVALRGDPPRGAERFEPHPDG
FRNAAELTRALREAGHDRISVAAYPEFHPESASPAADLDNLKRKLDAGADSAITQFFFDN
AHFLRFRDLAAKAGIDAPIHPGILPIENFAKMKRFAAGCGASVPESLETAYANADEQGMT
ETLSRAICAEQCDALRSEGVEHIHFYTLNNPDLPYDVCRALGVEPQPLGAAAGGAA
>A0A3B0FRB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter phenanthrenivorans|TrEMBL
MSPPSLIDTHPNLSDAAPVALSYELFPPRSPAAAETLWTTIRELETTEPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIIGELLDTGVRGILALRGDLPKD
GGEPAAGSLRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPTRHPESPSEEHDVEVLL
AKQRSGADFAITQVFFHTEQYADLLTRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAPELLERMAAADSDLERLHIGVDATVDLANAALDAGAPGIHIYTFNEHQSALEVLDKLA
LPRRSHASLRRHSTAPQLAS
>B0T509|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. (strain K31)|TrEMBL
MTAPPSSPRRVLGPVARAGERTDRPRVSFEFFPPKTEQMEENLWAAIKRLAPLDPAFVSV
TYGAGGSTRERTHRTVKRILEETSLKPAAHLTCVGASRAEVDEVIREYWETGVRHVVSLR
GDPPPGEGGIGGVYVPREDGYKNATELTAALTAIAPFNVLVGVYPEKHPESPSIEHDIEV
LKAKVDAGATMAISQFFFDTDAFLRFVDKVRAAGITIPIVPGVMPVTNFKGLVKMSKACG
TAVPDWLTKLFDGLDDDADTRRLIACSVAAEMCAKLQEQGFSDFHFYTLNRADLVYAICR
VLGVRETVPAPSPISAEAAA
>A0A353RS91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
FFDNDKFYAFREKAERAGINVPIEAGIMPITNLHQIERTVALSGASVPAKLSRLFSRYSD
NPKALFDAGIFYATEQIMDLIDHDVRGIHLYTMNNVETATRISDAIQNVLEAENTPKNAV
>A0A0H3FZX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymomonas mobilis subsp. mobilis (strain ATCC 10988 / DSM 424 / LMG 404 / NCIMB 8938 / NRRL B-806 / ZM1)|TrEMBL
MERILRENPNFVAEPFLGEKEPHISFEFFPPKNEEADKLLWQSVERLAPLKPRFMSVTYG
AGGSTRERTRATVTRIARETTIPAVAHLTCVNASRDEIDDIARDYWDAGIRHIVALRGDP
PGGERFQARPDGYANAVELVEGLKRIAPFEISVACYPETHPQALSPEADIEFLKRKFDAG
ATRAISQFFLSADVFLRFRDRVAAAGITAEILPGIMPTSNISGLRRMADSCGIAIPEKLG
RLMESLDKDDPSVKQMVSMAVTSDLCSQLAREGVDSFHFYTMNRAEITSALCRLLGRQPV
A
>A0A2P7SMF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium soli|TrEMBL
MNNFGFSRRPDIGGKISVSFEFFPPKTEEMETRLWDTVTRLEPLQPEFVSVTYGAGGSTR
ERTARTVKRILTETTLTPAAHLTCVDAVRGEVDKVIGEFVDMGVTRFVALRGDPVEGVGA
CYSPHPGGYANGAELVGALKKAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYVPIVPGVLPVHNFAQVARFSERAGAHVPAWLAERFD
GLENDPQTHALVAAAVAAEQVLDLVERGVDDFHFYTMNRADLSVAICHMIGIRAHAVSAG
GPSSAAA
>A0A2I0AXM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apostasia shenzhenica|TrEMBL
MKVIERIREAVVGEGRTVSSFEFFPPKTEEGVENLFERMDRMVSHNPNFCDITWGDGGST
ADLTFYIANRMQNMLCVSRSPILFFVRSARSLFSSMGSLFLIVFMQETSLTVRASLFKLR
VDCLRSGSGITNSLSDASSSTFYHLQN
>A0A853EN86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sanguibacter inulinus|TrEMBL
MTASDVPPTPAGGGSATAPPGRPAARPSRQRPTISFELMPPRNPAAAPKFWSTVDHLIAA
RPDFVSVTYGAAGGDRTTAQTVVRRILEHAPVLPIAHLTCVGASRDNVAEVIDEFLAEGV
RSFLALRGDPPRDQPDWEPHPEGINSSDELVALLREVEAQRCADDPSSALRSAARPLTIA
VATFLDGNAAAGTTRSQEVQRLLEKQQAGADFAITQLFYEADSYVGFVDEARRAGVTLPI
LAGLLPMTDPARLARVETLTGVPAPRALVRDLESLADPAARHARGIRASVELAEAVLAAG
APGLHVYTFNKHEAALDLLEGVHLGGGPAHPAPADAGPDLASGPWVGASQPTAALI
>A0A7U9X6X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKISDLLQKKEVTISCELFPPKKGSELEKAHEIVREMAKVKPSFMSVTYGASGGISEHTV
DLANEVQNVNGVLALAHLTCASSGRDKIQEVLKELKEHQIENILALRGDIPEHVEFPLPN
QYHHASELIEEIKNFGDFCIGGACYPEGHPEAESLEADIDNLKRKVEAGCEFLTTQMFFD
NNILYNFLYRTLKRGIEVPVIAGIMPVTNVKQIRRITSLSGTILPQRFRAIVERFADHPA
ALKQAGIAYATDQIIDLIANGVNHVHIYTMNKPDVAGAIFRNLSEIYNLPGQ
>A0A8J6N0C1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfacyla euxinica|TrEMBL
MVSAFKKALNSGKFVVTSEVAPPKGTNLDKMAHHIELLKDKVDAMNVTDHQSSVMRFPSL
GGALLVKEMGGEPILQMTCRDRNRMALEADLLFASQRGINNVLCLTGDAVMFGDHKEAKG
VFDLDSSQLMAAIRRLEKGEDLGGNKLDGGVSFCAGAIVTPEANPLEPQLIKFEKK
>I2HPH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. 5B6|TrEMBL
MGLLQDLEERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIADLGADITGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTEKEVKIRREEEVI
SVSSERTEPGLNEIAAKKRSIIVELDPPKKLNFEKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A7X6CSM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium HV4-5-C5C|TrEMBL
MKTADLYKQKTVLSYEVFPPRPSSSVQTVYQTINELKALEPDFISVTYGARGSLNHQDSF
QIAAAIRAAGLESVAHLPCLELTRQDLYQKLEQLQGLGIENILALRGDLPAGQYRPGDFP
HAADMIAFIKAHGNFNILAACYPEGHIECPDRIQDIRYLKAKVDAGADRLISQLFFDNDH
FYAFMERCQLAGIQVPIAAGIMPVINKSQIEHMTSICGVELPRKFSAMMARYEHNPVAMR
DAGIAYAVDQIVDLIAQGAAGIHLYTMNNPLIARRIHAAIQNLI
>A0A7M1Q7F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. MCCC 1A13316|TrEMBL
MSTPYPLGISFEFFPPNTEVGREKLMGVRDALAEHKPRFFSVTYGAGGSTQARTLNTVRA
VREAGISTAPHLSCIGSEKAQLRDLLAQYREEGIDSIVALRGDLPSGMGGIGELRYANEL
VAFIREETGDHFEIAVAAYPESHPQAPSFERDLDNFARKVKAGADLAITQYFFSADAYFH
FVERARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAKFG
TEVVSRLCQRLLEGGAPGLHFYTLNQADPCLRILDNLDGSLAAR
>A0A022W1V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichophyton rubrum CBS 288.86|TrEMBL
MSQALRPLFVTVTWGAGGSTAARSLELAEICQRQLGLTTCLHLTCTNMNRTLIDEALEET
KALGIRNILALRGDPPRSEEYNIDGEDDSNKDFNYAVDLVRYIRKKYGDYFCIGVAGYPE
GHADESHPEVQDLLKDLPYLIEKTQAGADFIMTQLTYDIEAYKKYEALLRNHESGTFKTI
PIIPGLMPIQNYHTLTRVTKLSHAKIPPQILAKVEACKADDEAVKRVGVDVVSDLVENIK
KVATPGHRGFHFYTLNLEKSVSFILERCNLIPPSSEAPSDSELDFESAVYAASGASNGVA
TPDGRSTNVNRLRASSMNSQPHNRVIVDRLTRASDRSERSSTVHETSAQTAGYPALNPPN
RNTALQISEGLGSLGREATWDDFPNGRWGDARSPAFGEIDGYGPSLHVTAQVARKLWGTP
TSRDDISNIFKRLLSGELHVVPWSEGGAGEEGGLNPETATIKAELLKLVEGRGWWTLASQ
PAVNGVRNDHPVFGWGPRGEGFVFQKAFVEFFCSGDDFHSKLKPLLQSYGHDEFAWFATN
AKGDFQSSTSPETSTQPPTDPSEVPFDADPLTEMDNGSVNAVTWGVFRGKEIVTPTIIEA
VSFRAWGEEAFGIWEEWRRVFPRGSPSEKLIREIKDDAWLVCVVGQRFGAGGDVGKESNE
EDGKLLWKVLAGE
>A0A2G1BWK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum sp. 4G03|TrEMBL
MKVIEHLEKANGTSLFSFEILPPLKGDTIESIFKNIDPLMEFNPPFIDVTYHREEYVYKE
LGDGLLKKQVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSETYFKPENDGHAYASELVTQIENLNKGRYLDDDLQNSSKTDFCIGVAGY
PEKHMEAPSLDSDIHFLKKKIKNGANYVVTQMFFDNQKYFEFVEKCREEGITVPIIPGLK
PISTKKQLNLIPHRFKVDLPDALVKEVVNCKSNAEVRQVGVEWCIAQSKELQQKGVPILH
YYSMGRSTNIQQIAEAVF
>A0A1Q3A165|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zygosaccharomyces rouxii|TrEMBL
MRISEKLQNHRSKSTKPTFSFEYFVPKTTQGVQNLYDRMDRMYQSTLPQFIDVTWNAGGG
VLSQLTTDLVETSQSVLGLETCMHLTCTNMPVSQIDDALESARLSGCQNILALRGDPPVN
SDSWQPVEGGFQYAKDLVRYIRDKYGDYFDIGVAGYPEGHPETAGDDETLLDHLKEKVDA
GANFIITQMFYDADLFIKWCQRVRAKGVDVPLIPGIMPITTYAAFLRRANWCDVHIPQEY
FDRLDPIKDDDQLVREVGTDLIVSLCQKLLDSGYVSHLHIYTMNLEKAPQMILDRMELLP
SHDEPLDNHLAILPWRKSLNPQRRNEEVRPIFWQRRPYSYVARTSQWSVDEFPNGRFGDS
SSPAFGDLDLCGASLIRQSGKKSLELWSAPNSMEDIAQLVINYLRGELKYLPWSDTSLNH
EVDDILPELVTLNQKLIITINSQPQLNGVKSSHPVHGWGPRDGYVYQKMYLEFLLPKEKL
SKLHDCLVNDVMLTYFAVDHNGNLTTNHQDGTRANAVTWGIFPGREVLQPTIVEKVSFLA
WKQEFYHICEEWKLNFINHRCDQSVKLLQHLIDDYVLVNIVDNDFISPENRIFNLLSSI
>A0A3C0VRN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
HPESADSWSDIDNMKYKVEAGCDFLTTQMFFDNNIFFNYLYKLRDAGIRVPVVAGIMPVT
NAKQMERIHKLSQAFLPHRFVALLDKFHDNPAAMRQAGIAYATEQIIDLIASGINNIHIY
TMNKPETAAEIQENLSEIIPSCKKN
>A0A3D3U7A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKVNEILSNGKITLSFEVFPPKTDAQFESVRQATIDVAALKPSYMSVTYGAGGNTRKNTV
AIAKGIQDTTGVTTIAHLTCVGATKENIHNTLDEMKAAGIENVLALRGDRPRDFEGDPFV
DFHYASELVSEIKAYGDFCVGGACYPEGHVEAANKSEDIINLKKKVDAGCEFLTTQMFFD
NNIFFNFLYRVREQGISVPVIPGIMPITRAKQVETARDLSGCSMPQRFLNLVDRFGSNPK
AMEQAGIAYATDQIIDLIANGINHIHVYSMNKPQIAEAIQKNLSEILK
>A0A117RWG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DSM 15324|TrEMBL
MALGTASTRTDRARTVRDTLATGKTTYSFEFTAPKTPKGERSLWDALRRVEAVAPDFVSV
TYGAGGSTRATTVKETEQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVLPVTSVKMLERLPQLSNAHI
PDVLKERILTAKEDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNSSTATLEIYENLG
LHHPPQA
>A0A255H9Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enemella dayhoffiae|TrEMBL
MSDLARPTIAEVLATARGPLFSFEFFPPASEEAERTLWQTVRELEALGPDFVSVTYGANG
STRDRTIHATRQISRETTLRTMGHLTCVSQSRDDVRRVVGAYADAGVRHILAVRGDPPGG
PTAPWQAHPDGLQNATELVRLIASLGDFCIGVAAFPDVHPEQSDADLDARILVDKANAGA
SFAITQLFFTADDYFGLVERVRALGCDIPIIPGIMPVTNLRQIERFAELSGAALPERVTA
RLRAAGDPDSVRAVGIELGTELSAELLAGGAPGLHFFTQNRSRATREIYARLQLTRQR
>A0A524Q6W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chrysiogenales bacterium|TrEMBL
MKIKDLFLKETFVLSFEVFPPVRAGNTVELFNTIDELVMIDPNFISVTYGAGGSTQDMTF
EIASRIKNHVGTEALTHLTCVQATKKDIIGILDHLDRENIRNILALRGDPPQGEKSFTKI
DGGFGYANELVEFINTHGDFSIGVAGYPEGHVESPDLDADMENLKKKVDAGADFIITQLF
FNNGDFYRFRDRAASRGIMVPIIPGIFPIFNFKQIAKIASLCGATIPKPLFDQLAAVSER
SDEVAKYGVDYAVRQSEDLLGNGIPGLHFYSMNRSNHVTNIIRQLKIDGKPLYESEKRII
GGAV
>A0A4V3S045|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKISELLQTKQVTISCELFPPKKGSELEKSHEIVKEMAKVKPSFMSVTYGASGGISEHTV
DLANEVQNVNGILALAHLTCASSGRDKIQEVLKELQEHHIENILALRGDIPEDVDFPLPN
QYHHASELIEEIKNFGDFCIGGACYPEGHPEAESLEADIDNLKRKVDAGCEFLTTQMFFD
NNILYNFLYKTLKRGIEVPIIAGIMPVTNVKQIKRITSLSGTILPQRFCAIVERFADYPA
ALKQAGIAYATDQIIDLIANGVNHVHIYTMNKPDVAGAIFHNLSEIYNLPG
>A0A173KUU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. EP60837|TrEMBL
MTLSFPSVEEARRALDAPLYADLAGDLNVSFEFFPPKTEKMEEQLWSAIETLTPLAPKFV
SVTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASKAEIDEVVDAYWEAGVRHIVA
LRGDPPEAGCKFEPHPEGYQGAAELVEGLRKRHPFEISVAAYPETHPDALNAQSDIDNLK
RKLDAGASRAITQFFFEPDTFFRFRDTVAAAGIDAEIIPGIMPVSNFAAVQRMSAMCNTD
VPGWMGKLFEGLDDLPAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPQVAAMA
>A0A316LZK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKITSIFEKEEITVSFEVFPPKTTTNYEAVEKAALGVAALKPSYMSVTYGAGGSTRGYTI
KIAEKIQKEQQVTTIAHLTCVGATKADIHAALGQMKEAGIENLLALRGDRPKDFEGDPYV
DYHHASELVETIREYGDFCVGGACYPEGHPDAATKKEDILNLKKKVDAGCEFLTTQMFFD
NNIFYNFLYKAREAGILVPVIPGIMPITRANQVANAVRLSGCNVPERFRSIVDCFGDNPA
AMQQAGIAYATDQIIDLIANGVNHIHVYSMNKPEVAKGICDNLSAIIH
>A0A3N4LFR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terfezia boudieri ATCC MYA-4762|TrEMBL
MHIKDKLAEADRTHQPMFSFEYYVPKTAQGMQNLYDRIDKMHAFGPQFIDITWNAGGRLS
NLTCDMVNVAQSVYGLETCMHLTCTGMPKEKIDNALKEAYKAGCQNILALRGDPPREKEK
WEAVSGGFHYAKDLVKHIRSTYGDYFDIGVAGYPEGCEDQDDPDLLLEHLKEKVDAGASF
IITQMFYDVDIFLDWVKKCRAIGITVPIIPGIMPIQTYAAFMRRAQWTRCRIPPRWLEML
EPVKSDDVAVRDIGKDLVVEMCQKILDSGILYLHFYTMNLAQATRMILQGLDLLPSVGVV
TPSLPWRQSLGLNRKDENVRPIFWKNRNKSYVQRTQEWDEFPNGRWGDSRSPAFGELDAY
GIGLRGTNEQNIKLWGHPKTVRDISKLFVRYVSGELSSLPWSDQPITVEVDSIKEQLLEL
NKRGFLTINSQPAVNGVKSSHKVFGWGPRNGYVYQKAYLELLIHPELLSELITRIERNPD
LTYYSVDEKGNLKTNSGDGGPNAVTWGVYPGKEIIQPTVVESISFLAWKDEAYRLGKDWA
SCYAAASPSRHLINSVMESWYLVNIVHNDFHDSHGIFSLFDGLEVPDLDQTIEISEALEE
KKEAHAIPNEKPPTTTNGITKALLAEATNGVPATAAPAVETSQPKVVN
>A0A2T7JR31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CS081A|TrEMBL
MALGTASVRSDRARTVRDILASGGTSYSFEFYAPRTEKGEQSLWRAMRRVEAVGPSFVSV
TYGAGGTTRGGTVKATQKIASDSTLTPVAHLTAVGQSVAELRNILGQYADAGIRNMLALR
GDPPGDPLGEWIEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVVKAGCETPIIPEVMPVVNVKTLDRLPQLSNAAF
PARVKERILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A374TFL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp. TF12-30|TrEMBL
MNIAEFLHQKGDKRGFSFEVLPPLKGNGTAALFRTIDSLKDFDPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHVICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHSNATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGADYAITQLFYDNEKFYAFVEKARQMGITIPIVPALK
PFAKLSQLTMVPKTFHCDIPEALAQEVLKCKSDEDAKALGIEWTTAQVKDLFDHGYNHIH
FFTVSAVDSVKQIAKILF
>A0A351TL09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MLQNVFEQKSTLSFEIFPPKKDGEFESAFRVLDSLGKLNPDFISVTYGAGGSRSGKTIEI
ASYIQNELRINAMAHITCVGSKKEDILQVSAALQEHNVNYVLALRGDRPKDMSDEQFASR
DFAHANDMMHFLKENTGLHMAGACYPEKHYECFSMESDLNNLLRKQEAGAEFLISQLFFD
NDYYYSFLEKAGKKGITIPISAGIMPITTANQLGTTVSLSGSSVPKTLADLIANYGDNKD
EMRKAGIDYAIRQIRDLQENGIKHIHIYTMNKPKMAEEIVNAIYR
>A0A1S2QA09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces monashensis|TrEMBL
MAAEALRTLLGRVRYEVLPARATEAKVLAHVPRDIVVTVTASPVKGLEPTLALTERLAAH
GYRVVPHLPARLLRDDAHLKDVAERLRATGIDDLFVPAGDADPPAGPYEGALPVLRRLAE
LGSPFEELGITGYPESHPVIHDDITVQSMWDKRAHATYIVSNLCFDPRVLGDWITRIRRR
AITLPVYVGVAGPVQRAKLLAMATKIGVGESTRFLTRHPAWFLRLAAPGGYAPERLLTRG
AQALTGPSAGVAGLHLFTFNQLAETERWRRALLDRLGG
>A0A7S1YRZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ditylum brightwellii|TrEMBL
WGAAGSTSARTLAVASHAQRYLCVDVLMHLTCTGVTREQLAQALSQAKSCGVHNILALRG
DPPKGKRAWEKDDVSGGECDRAIDLVRLTRKLHGSYFGIAVAGHPEGHPASYSPEKEMAH
LKDKMDAGADFIITQFFYDASVFLAYVRNCRENGITCPILPGIMPIQSYSSFARMTEFCG
ISVPPSVMQRLEPVKHDDEAVKEIGCQIASDMCHEILGAKEEEGAVDGVHFYTLNLERSV
TLILTSMGAIDLVGTIAAANSTTATPADSPQKQNGEKSDKHANKSSPSDPSSSMAVLPPT
RRQFPWRPSAMASRSKEDVRPINWANRPKSYVMRTDDWDEFPNGRWGDATSPAFGELSDV
SHFYSFTLGSDDDRRAMLGHNPTTDKDVFEVFARYVEGDVPHIPWCETPLQPESFLIQRQ
LAALNRAGFLTVNSQPPVNGAHSTHPTFGWGGAGGYVYQKAYCEFFVSPDNANRLVSMVT
DHPSMNLYAVNNAGNELRVGVEEGGATALTWGVFPNREILQPTIFDPSTFLVWAEEAFSL
WTTMWLNLYEMDSPSYDLIETIRDTYYLVAIIDNNYIAGSSVENGGINNKNSNSLWQKLM
ETSHAVVQ
>A0A7Y5ACK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CM27|TrEMBL
MSLLKTALREQHFVCVMEFVPKPSAERFAAMEAIMARAHLCGWPMTVAIGDRVGSPLDMS
PLDAHASFSKPLPVLPHFSGKDRERQHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYCEEEGGAQYFKAEKKLAAGADFLTLQLGF
DADKHQEAMHWMNRQASPKPMLACLMSLTHGRAAMLDHVAGVTVSPSMHDMLEAEAAQSK
AFTQARSVDRLALQIIGVKLMGYAGVHLSGIHELKQLLALEARIEHWQTQVHTLEQWAPA
WHESWQLPGLPAVSFHPPQAAWRAGESRIDASFKEKARYHLMHGMHSLLFSRGNALSKAF
GWAVSQPLWATRLGAQVLHSVERSVKRPLLGCDTCGTCRLEDTLYICPESCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVRQTAVLTERLIPCIEVQTRHRSSWPQWFAAQTP
RRISPQPTPRTQPES
>A0A7C7CDZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKIIDKINKRLNSDKVFYSFEYFPPKTQRGKQNLYFKLEKMSKLEPLFIDVTWGAGGSTS
DLTLEICSNTQNILSLESQMHLTCTNIQEDVLKQTLKTAKENNIRNILALRGDPPLGNDK
WEASDSNFKHAIDLIKYLRKNYGDYFGISVAGYPEGHPESDYNADLNYLKQKVDAGADFV
ITQLFYDVDLFLKFYKDCRAIGINCPIIPGILPIVNYANFKKLTDFCKIKIPEYILNDLE
PIKNDDKKVSDYGIELAIKLCKKLIANDIKFLHFYTLNRENSCVQIIEGLDLTKDLPGKR
AFPWKPRIGIEESVRPIFWNNTIEYYIQRTSDWNQFPNGRWGSIHDAQYGEIKDYHLFSI
GLGTVENKREMWGEVKNFSDVSEVFINFLNLKIKYIPWCDNLANETSTINEKLIEINKLG
YLTINSQPNINAMPSNHENGWGGSDGYLYQKAYLELFTSKDRLDPLLSKIDSDRYSYCAV
NKQGDIITNCKDATLAVTWGVFPKTEIIQPTIVDYESFLIWKEDAFNLWLTEWANIYHKK
TASYKLIQEIHDNYYLVFFVDNEYIDGDIFDLFNT
>A0A246KE26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas diminuta|TrEMBL
MAPSSLAEARALLLSPLGPVARAGSNRSAVNVSFEFFPPKSDEAEANLWKAIRRLEPLNP
AFVSVTYGAGGSTRERTHRTVQRIISETTLRPAAHLTCVEASRAEVDEVIEGYKAIGVDH
IVALRGDPPGSAGIGGAYTPRADGYANATELTAAIASIGGFEVTVGAYPEKHPESPSIDH
DIEVLKAKVDAGATRAVTQFFFDIEAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLKRMT
AACGAALPDWLAGHFDGLDDDPETRKLLAASIAAETCARLQEEGFSDFHFYTLNRAELVY
AICRVLGVRETKAVA
>A0A166UTN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum tofieldiae|TrEMBL
MHIKSMLDETRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREHEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGATF
IVTQMFYDADNFIRWVGKVRERGITVPIIPGIMPIATYSSFLRRAKHMNCKVPEEWMAAL
EPIKNDDVAVREVGKGLVAEMCRKIVAAGIHHLHFYTMNLAQATRMVLEELNWMPTSDRP
VKHALPWKQSLAHGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPKSIKDIANIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSTHPVHGWGPANGYVYQKAYLELLVHPDVYAEIVSRVEKNP
DMTYYATTKNGNLKYNATHDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGIDW
AHCFEAGTPSRVLVERIMNDWYLINIVNNDFHQKTALFDLLEGLEVKEYTDIPAEPQTNG
AAKEQPLETNGNSVPVTAN
>A0A2N2WD91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-6|TrEMBL
MIVAELLRNTKQTLFSFELLPPLKGDNISAIYDTINPLMDFSPSYINVTYHREELVYKQR
PDGLLEPRKVRKRPGTVGITAAIMHKYKVEVVPHMICAGFNREETENALIDLHFIGADNI
LVLRGDADKNSRRFESEPDGHEHALGLLQQVMKMNKGKYLDEDMLYQTPTRFSAGVAGYP
EKHAEAPNLGSDLQWLKAKVDAGAEYIVTQMFFDNAVFISFVKRCREAGINVPIVPGLKP
VSIKNHLTILPGTFHVDIPEALAREVMAAPDNRAVRQIGIEWTELQARELKAAGVPSIHF
YTMGKSDNIYEIVKRVF
>A0A0N7JEA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. PACM 27299|TrEMBL
MKIVDHISNAKGKTLFSFELLPPIKGQSIKGIFDAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNKYKVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDNAFIPTPDGHAYASELLQHVVDMNNGRYLHDDMENSEKTDFCIGVAGY
PEKHYESPNLDTDFKYLKHKVDLGADFIVTQMFFDNKKYKALVDKCRENGINVPIIPGLK
PITSSKQLISLPKIFHLDIPIELSEAIQSCKSEKDVKEVGIEWMIHQCKELKEMGAPVLH
FYTMGNPEPTKKIANAVF
>A0A543GG43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia cypriaca|TrEMBL
MSTETNEPVTHSEPSVLSKREALVRALRNASYEVLPFKKTEAAVFEHVPPDVALTVTTTE
AKGLGPTVDLAVRLSRHGYTAAPHLAARLVRDGAHLTDVVAQLREAGVSSVFVIGGDAAE
PAGTFPDALSLLRGLDEIGHPFTTVGIGGYPEGHGHIPDDVVDKALEQKAPHATQVITQL
CFDADTTVSWARSIQARGVALPVRVGIPGAVSRQKLVRITAGLGLGQSARFLKKQQSMLW
RFFLPGGYSPDRLVRRLTPSFGDPGTNLAGFHVFTFNELEKTQTWRQEWLARLEEA
>A0A0G3XBQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagerythrobacter marensis|TrEMBL
MSPTFDQMQEARTALDAPLFSGLAGDIDVSFEFFPPKTEKMAQTLWDSVQTLSPLGPRFV
SVTYGAGGSTRERTHEQVVRINREAGIPAAAHLTCVEATREQIDEVARHYWESGIRHVVA
LRGDPPDGQAHYVPHPGGYANAAELTAGLKAVAPFEISVAAYPEVHPDARDAAADLDNLK
RKFDAGATRAITQFFFEPECFFRFRDKALAAGIDGEIVPGIMPVMSFASVQRMAGLCGTA
IPGWMAGLFDGLDERPAARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRPQGDDR
>A0A4Y9KHV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus saprophyticus|TrEMBL
MSQLLNKLKSNILVADGAIGTILYSEGLDTCPEAYNLNHPDKVERIHRTYIEAGADIIQT
NTYGANFEKLKVFGLEHRVKDIHQAAVKIAKKAANDDTFILGTVGGFRGIKQEDLELSSI
QYHTEIQVETLVNAGVDGILFETYYDLQELTNIIEATKRKYDIPIIAQLTALNTNYLRDG
TEINHALQQVTSSGADIVGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSQF
KYSDNASYFGKVAKQLINEGVRLIGGCCGTTPEHIQYIKSSVAGLNPVTQKDVIPITKYI
NNTEKEPQKQNLKSKVENRPTIIVELDTPKHLDTETFFRNIKKLDDAKIDAVTLADNSLA
TVRISNVAAASIIKQRYDIEPLVHITCRDRNLIGLQSHLLGLSLLDINEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKTKTSFNIAGAFDPNVRKLDGAVRR
LEKKLESGMHYFITQPVYSKEKIKEVYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEEILEQFEAVKDDKGKTKDLSLKLSKELIDTVHEYFNGLYLITPFQKVDYTLELANY
SKTITSTKQEAIL
>E8TF31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium ciceri biovar biserrulae (strain HAMBI 2942 / LMG 23838 / WSM1271)|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A1E5IUD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella colwelliana|TrEMBL
MAFHHAQHANSLNQSLSELNGDINVSFEFFPPATPEMEKILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETDLVAAPHLTLVDASDEELVELAKHYWNSGVRDIVALRGD
LPDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDATNAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFKQLKRFAGMTNVSIPGWLHKQFE
GLDDDPSTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A1M5LJV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrocarboniphaga daqingensis|TrEMBL
MNPTAKPHFSLELFPPRTPEGTAKLPATLQTLAATGPEFFSVTYGAGGSDQNGTYDTLMT
VVRETGVEAAPHLTCIGSTRQRIAQLLSQYRDAGVKRIVALRGDLPATAYSPAAPGEFHF
ANELVAFIRETHGDHFRIEVAAYPELHPQATSAKADFGHFVDKVHAGADAAITQYFFNAD
AYFDFMDRCAAAGVTVPVVPGIMPIVNAAQLIRFSAGCGAEIPRWLRLRIDELADDKAAL
QDFGTDVVARLCEKLLAGGAPSLHFYTLNQAEPTLRLCRALGMA
>A0A2R2IUV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium sp. F49|TrEMBL
MTQTPRTFSFEFFPPKTPEGIAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGHAAAPHLSCIGSTRENIAAILDEYRNNGIRHLVALRGDIPSGMVAAGEFRYANELV
SFIREQHGEHFHIEVAAYPEFHPQARSAEDDINNFVRKVRAGANSAMTQYFFNADAYFRF
VDEIQARGVDIPVVPGIMPISNFGQLCRFSDMCGAEVPRWLRQRMQAYYDDTASIRALGL
DVVTELCDRLLQGGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A0E3CJ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xylella fastidiosa|TrEMBL
MIPISFEFYPPKNDDQRAQLDRTANRLRAFAPEYVSCTFGAGGSTLSYTSETVRHLSQHH
GFDAAPHLSCVGGSRQEIRELLKLYRAIGCQRIVALRGDLPSGMGHPGDLRYAADLITFI
RAEHGDHFHLEIGAYPETHPQASNTLNDLHYFKAKVDAGADAAITQYFYNPDAYFHFVDA
VQRLGVTIPIVAGVMPISNFDQLRHFSEQCGAEIPRWITKKMQAYGDDTKSIRAFGADVV
TALCERLIAGGAPGLHFYTLNLAKPSTQVLQRLGY
>A0A142EPZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus sanaruensis|TrEMBL
MKITEHLQNAKSTLFSFEILPPLKGQSLKDLLEGISPLMEFKPPFVDVTYHREEYIYKKH
PNGLLEKVSTKKRPGTVGICAAIMNRFHVDAVPHVLCGGFTKEETENVLIDLNFIGVDNV
LALRGDAPKAERFTAEPEGHSFASELVDQIVRMNQGKYLHEETENSFHTDFCVGVAGYPE
KHFEAPSLKFDLKYLKEKVDRGAEYIVTQMFFDNQKYFDYVKKVREAGITVPIIPGIKPI
TTLGQITMLPRTFFLDLPDALTDELEKCKTNSEVKEVGIAWAIEQCKELIQADAPSLHFY
TMSKADATYQIAKAVF
>A0A2N3F4L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium HGW-Actinobacteria-7|TrEMBL
MSRLRDALDRGEFVITGEVAPPHGTDYSAMRASLDTLGPLCHAINITDNQGATLHLSSLA
ASKAALEAGYEPIFQQTCRDRNRLALQSDLLAAWTLGLENVLMVTGDDPRSGDHTKAKGV
FDLDSTQLLAVAKGMNEGVDMNGSELTGATGFLLGGAMFPEAEPWEIQLERAVQKAEAGA
TFFQTQAVMDTDKLARAVDALAPYGVKLIASILLLKNGRVIDFVNTKLAGMMIPDHIGSR
IKGAADPMAEAIALATEQVREIRDIAHGVHVMPLGADDVVERILEGAGL
>A0A258B041|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium 12-59-8|TrEMBL
MHIADILQDQRPTLSFEFFPPKSAEAFEALYQTIGELEAFKPSFVSVTYGAGGSTRELTH
DLVVRIKTTTSLDAVPHLTCVCHSEADIHAILERYAKAGVSNILALGGDPPKNLANYDRA
KDAFQHAADLVAFIKKFNDSGAHPDKRGFGIGVAGFPEGHPTTPNRVLEMDHLKAKVDAG
ADYICTQLFFDNHDFFDFRERCQLAGINIPIIAGIMPITSASGMRRMAELAAGARYPAKL
LRAIQRCGGDEAAVQKVGIHYATEQCHDLLDHGVDGIHFYTLNKSHSTREIYSSLGIRDS
AAVRPQS
>A0A8H3C168|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MPPFTRSVTKARLRDVSTPPRTYADRVLSQLQRDSLWDEQAAPRSFSSARSLKDLIEITV
VFVVATTLDIIKDIVMISKKPIGWLLAAYLILMALSGTSDLFVKTLMSPVCTLPIISGRI
DYCTRDAFSRRVSPDFPQLASLQSRLEDVMDDSASSSIVAVDMKNSELAVRDLTTLVKLS
SLVAKDSLVDRLNEFVVDAKATGRNLQRFGGRVGGAVDQIITMNEYVLKLLENTVKDSHP
QVSDGTIQRVMNAVSPIKPAGPHIIAARRKEVETMWYQATGMMESTIRKLIHEAEINIVA
LDKLEGQLDLINEMILREDEGIRAQAEEVLGELWTKLGGNKKKLHNFRSHRMLLNEIRVY
RKRALAHVSSTLVQLQGLSADLDDLRQRVATPALAGEEAGIPLEVHIGSMQKGTERLLES
RKRAREREDAYLQKIPYIVMKVTEKIQQAEKDGRIWWSFEYFPPRTAQGLQNLLDRIERM
RALGPEFIDITWNAGGRTSDLTSELVKTCQGAIGIETCMHLTCTNMHQEKVDIALREAKA
NGCRNILALRGDPPSGQEEWTSVEGGFQHGIDLVKYIRREYGNYFDIAVAGFPQTIQLPE
AEAKQEMQWLKEKCDAGANFIFTQMFYDADVFIRWVKAAREAGITIPIVPGINPIQTWNG
FIRATSLSGTEIPQDLMDTLEPHKNNDEKVRELGIKIVADLCRKILGADIGIKGLHFYTM
NLEKGTKMLLEELNLVPRVETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWD
EYPNGRFGDSRSPAYGELDGYGIWIKQTPEEGRKIWGTPTTIDDVKSLFAKFCSKEIKAL
PWSDQPPSTEMLVIGQQLTRMNELGYLTINSQPAVNGVRSDDKAFGWGPKNGYVYQKAYL
EFFVHPDQLQTLIKRIERDTNVTYYAINRQGDLKTNSTSDGPTAVTWGVFPGKEVVQPTI
VEAVSFMAWKDEAFELGCQWAKIYEPGSPSRKLIENMMDEYFLVNLVHNDFHDREAIFRP
FFADAGLKTNGDTEAPAINGIKQVNGLTNGHTTTVHA
>A0A2D5HMH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MTTKSNLKLALENKRFVITAETSPPDAADAESVIKRAGCLKNIVDAVNVTDGAGAKPHMS
ALATAAILAKNGIEPVLQFTTRDRNRIAIQGDLIGGWALGIPNILCLYGDDITVGDQPDS
KKVHDIDSKQLMETAHIMKSDGTFPTGRKIDPKPELFIGAADLPRMPDKDFNASGLLAKI
SSGANFFQTQFAFDIDVLKEYMKVINDAGVTEKAYYIVGLGPLASAKSAKWMDANLFGVN
IPEKVIKRIESAENEKAEGQKICIELLEQLREIEGIHGAHLMGPRQEQSIADLVSQAGLG
V
>A0A8H5B379|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tulosesus angulatus|TrEMBL
MKLSEKINAHGGSRPFYTFEFFPPRTNQGFENLVARISRLATLDPLAISVTWGAGGSTKD
RSLELAGITQSHPYSLATMLHLTCTNMQEGLIDDVLESVKDRGIQNILALRGDPPRGKEE
WIPSDPRFTHAIDLVRYIRSVPEYSSHFCIGVAGYPDGHPDSPLSEDAEIDNLKAKVDAG
ADFIITQLFYDVDQFLRWVKKVRAKGITVPIIPGIMPVQTYATFARLTKLCGTKVPKKLE
DELTPLKHDDRLVKDYGVNYAIEMIRKIHSDGDIQGFHFCTLNLEKSVQRVLEGLQWTGA
VNEVSNKLIADIPAPLTENSQGTEFLITPSSAANNATSGLVSFSKTKTKNEMGKGEVNDA
ASWDDFPNGRFGDFKSPAFGNQDPWGGSGMTRTDIHPQWANPKSSEDLTRMFMSYLESKI
TTTPFSDGALCPESVTILPQLKKLTQRGWWTVGSQPAVDGISSADETFGWGPRSGWVFQK
AFVEFFCDGKDADAIEAYIAEKGQGWVHYFMANGKGDFRGNVAGDGRNAVTWGIFPGSEI
LQSTIIERESFITWKEEAFSIWKSWASFYRPASPERQLLDEVAKERWLVSIIHHDYKNAD
ALWTFLFDSELGF
>A0A8H2WSA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MPPFTRSVTKARLRDVSTPPRTYADRVLTQMQRDSLWDPKAPPRKFSDARGLKDLIEIAV
VFVVATVLDIVKDIVMISKKPIGWLLAAYLILMALSGTSDLFVKTFMSPVCKLPLISGRI
DYCTRDAFSRRFSPDFPKLASLQSRLEDVMDDSASSSIVAVDIKNSEMAVRDLTTLVKLS
SLVAKDALVDRLNEFVVDAKAAGRNLQRFGGRVGGAVDQIVTMNEYVLKLLENTVKDSQP
QISGGTVQRVMNAVSPIKTAGPQVIAARRKEVETMWYQATGMMESTIRKLILEAEVNIVG
LDKLEGDLDLINEMILREDEGIRAQAEEVLGELWTKLGGNKKKLNNFRSHRMLLNEIRIY
RKRALAHVSSTLVQLQGLSADLDDLRQRVATPALAGEEAGIPLEVHIGSMQKGTERLLEG
RKRAREREDAYLQKTPIIAMKVTEKIQQAEKDNRIWWSFEYFPPRTAQGLQNLLDRIERM
RGLGPEFVDITWNAGGRTSDLTSELVKTCQGMIGIETCMHLTCTNMHQEKVDVALREAKA
NGCRNILALRGDPPSGQEEWTSVEGGFQHGIDLVKHIRRGYGDYFDIAVAGFPQTIQLPE
AEAKQEMQWLKEKCDAGANFIFTQMFYDPDMFIRWVKAAREAGITIPIVPGINPIQTWNG
FIRATSLSGTDIPQDLMDILEPHKNNDEKVRELGTKIVADLCRKILDADIGIKGLHFYTM
NLEKGTKMLLEELNLVPRVETIKPLPWRQSLTPTRRTETIRPIFWANRTKSYLSRTENWD
EYPNGRFGDSRSPAYGELDGYGIWIKQTPEEGRKIWGTPTTIDDVKALFAKFCSQEIKAL
PWSDQPPSTEMLVIGQQLMRMNQLGYLTINSQPAVNGARSDDKAFGWGPKNGYVYQKAYL
EFFVRPDQLQTLIKRIERDTNVTYYAINKQGDLKTNSTSDGPNAVTWGVFPGKEVVQPTI
VEAVSFMAWKDEAFELGCQWAKIYEPGSPSRKLIEDMMDEYFLVNLVHNDFHDREAIFRP
FFADNGLKVNGDTEIPVTNGVKQVNGLVNGHSTAVRA
>A0A6H9GT48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa NIES-3804|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSRSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQEVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>A0A165TXB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neolentinus lepideus HHB14362 ss-1|TrEMBL
MKLTEKIAAYRLNRPFYTFEFFPPKTDEGFENLLSRVARLASLGPLALSVTWGAGGSTKD
RSLELAGLIQNVEKVDTILHLTCTNMEGGMVDDALRAAKERGIQNILALRGDPPRGEEYW
IPTDPRFTHGADLVSYIRSSPEFSSSFSIGVAAYPDGHADRDSDEDGELDYLKAKVDAGA
DFIMTQLFYDCDNFLRWLKKVRGKGITIPVIPSIMPLQTYASFLRLTKFCGSRVPDSVVS
ALEPIRHDDAQVKEYGIALAIDMVKRLTASGDVAGLHFCTLNLEKSVRRVIEGLGWAGGS
PEIRNKLITDMPNGADSIDFEATMTITPTSASDSATKGLIDSTSLPPDAGRGEINNASSW
DEYPNGRFGDFKSPAFGEQDQWGGPVITRGEALANWGQPKTVSDLTEIFLRHLRGEIDST
PFSHGPLSPESMLILKQLEKLNRKGWWTVGSQPAVDGVRSTDEVFGWGPPSGYVYQKGFV
EFFATQEDVDQIEKKIKEDGGGWVDYFAGNFEGQCRSNVPDGGRNAVTWGVFPGQEVLQT
TIIERESFLSWKDEAFSIWSEWATFYAPDSEERKLLEGIRDQRWLVSIVHHDYKEASALW
SFLGEL
>A6UBB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium medicae (strain WSM419)|TrEMBL
MNGRLPNAVDCRGIRFSFEYFPPKNDEMEAQLFQTVTALSVFAPAFVTVTYGAGGSTKAR
SLTTVKRMIGEMAIGNTAAHLTCVGAPKADVDAVVDEFVACGVRHFVALRGDPQGGIGSV
YEPFPGGYENAADLVKALRARGDFEISVSAYPEKHPESSDVAADIDMLKRKVDKGATRAL
TQFFFDNDDFERYLERVRRAGIGIPVVPGILPINNLAQVQKFAGLCGARVPESLISRLGP
LNDRPEERFREAAHIAAEQIADLVRRGVNDFHLYTMNRPQLVTAVCGLIGYEAERASAQP
VDTERSFRAAATG
>K9SYJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. PCC 7502|TrEMBL
MSFAAGFYPNFSNLSNLYNSFKANALNKNFLITAEVAPPRGCDPQPMISQAQLLKGRVHA
VNITDSSRAVLAMSPLAASVILQYQVGITTIYQLACRDRNVIALQGDLLGASALGLQNVL
ALTGDPVKAGDHPQARAVFDLESVRLLQAIAKLNQGQDINGRPLDQPTDLFAGAAVDPQS
SSWSGLQRRFERKLAAGAEFFQSQLITDFDLLDKFMQKLGNPSQKPILAGVFLLKSAKNA
QFINKYVPGVHIPDHIINRLAQAPIPLQEGIAIAAEQVKAAREICQGVHLMAVKTEHLIP
QILDLAGIPPLV
>A0A2E1FU44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MHPHPAPHGVSLNGLYPXNYTSEVQIKADRQSKLSFEVYPAKTEKAQKALLSELRLLSPY
RPTFISVTYGAGGKSQAGTADTAKQIQKTLNTDVMAHLTLAVQTRDDVLATADRFSAAGV
RQILALRGDQPHEAVSLPQNPFTDTVELIRCLAARGWDNIRTSAYPDIHKEATDADSDFD
WLLAKFDAGASEAVTQFFFNADNFFRLRDRLDRYGLAKKLIPGILVFREIEKMIGFAKKC
GVHIPARLHVELSRSRQTDVEEAHCLSILLDLLLRLSSQGVXQYHFYTLNKAQPLVTLLD
LLDLPKQGICAVADRQPETCY
>A0A368E3Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MSLTIDKLSSAAANWSIEVTPTGASKVESFADVLEPQTCVNVTFLPGSDPADTLAVACRL
HEEGMIPIPHIAARSIKDKAHLQDIISALAKQAYVSEVLVIGGGVDKPVGEFDSSIQILK
SGILQSNGIFKIGVAGHPEGSPDISNDAVRHALHEKNELAVKENLQMYIETQFCFEADMV
LEWEKRVREDGNQLPIRIGIPGPATIKTLFRFAQISGIGPSMKFIAKQARNVAKLMTVQS
PHLLLSGLAEGMAADHQCLIKHFHYYPFGGFLKTAKYAKAISDGNVHLSPKGGFEILETQ
>A6UAD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium medicae (strain WSM419)|TrEMBL
MSPDINPYDPGAPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPHDVYERAAIFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLSTPPHVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PLASAKTARWIRSNVPGIHIPDGIIRRLEGAQDQKKEGKQLCIDVMNEVKEIEGVSGVHV
MAYRQEEYVAEIVHESGVLRGRKPWKREAAPTDAMVAERLEHIREGREENQQQMAEAAAH
HPHETKQ
>A0A4Z1AKK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira dzoumogneensis|TrEMBL
MKKILEIYKTAKEPVYSFEFFPPKTPEGEVKLFEAVEELSKVDPGYITVTYGAGGSTRDK
TIRITSELAKKFSLPAAAHFTCVGGNKDEIRVILKQIRESGIENLMALRGDPPKGEDAFK
KVEGGFGYANELISFIKQEGFDFCMGAACYPEKHPEAASLESDVDNLKRKVDSGASYLVS
QLFFKNSNFESFLNLIRQKGISVPVIPGIMPITSFAQIERFKAMAACEFPEKLVSDLEEV
KEIPEEFYKRSIDFSVNQCRELVKMGAPGIHLYTLNQSPASLDIVRELKN
>A0A2D4VX70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR116 cluster bacterium|TrEMBL
MASTIEMISKAAADWSIEVTPTGATKIESFRDCLSPGTTVNVTFLPGTDPAETIAVAERL
HNDGMRPVPHLAARSLRDADQLDELLAAFTSRCGVEEVLCIGGGVDKPVGAFDATIQVLE
TGLIQKHGIRSVGVAGHPEGSPDITDEEIAAALAAKNALAARDGLNLYIETQFCFEADIV
LDWERRVRAAGNTLPIRIGIPGPATIKTLFRFAQISGIGPSMRFVAKQAKNVAKLMTVQS
PHMLITGLAEGMAADDACLIRHFHYYPFGGFARTAAYAGGVAEGNIELLPKGGFDVIAN
>A0A8G8R5C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMB3-12|TrEMBL
MTATPTTPPTDPDCRSSIPFSFELYPPKTDAATMALHATIDALAAARPKFISVTYGASGS
SRTSSLDVLRYIRRATIVDPMAHLTCVGSSHAEASSLIREFLDAGVSSFLALRGDPPEGL
TENDAFLGDLHSAGELVQLIHRVQAERVPYQETPIPGLPRARAVKTEREHVRIAVAAFPN
GHPRSRSTAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPV
TSPGRLRRILELSGEELPAELSIQLEVEPTLEGQREIGVSHAAALAEKLIAGGAPGLHLY
AFNQHETVLAVLDRAGALAPAQPVVSAHNPPPTHPSTSPADTRAGIHSTKDHY
>A0A7C7QK96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MRSSFKMALESGKFVVTSEVGPPKGTDLEKMVHHVEILKDRVDALNVTDHQSSVMRFPSL
GGALIIREMGGEPILQMTCRDRNRLALQADLLFAASRGINNVLCLTGDSVVLGDHKEAKG
VFDLDSSQLVAAIRRLEKGKDLGGNDLGGSASFCVGAIVTPEANPLEPQLIKFEKKVEAG
AEFIQTQAVYDLDNFKQFMDYARQFPVKILAGIILLTSAPMARFMNKNIAGVNVPQELID
EMASAPKGRVLEKGIEIAGRMIRRIREEKICDGVHIMAIGKEDRVPDIMVAAGLS
>A0A7Y3GID7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MSVKTPSKLEKILSEGHYAVTSECGPPRGSDPKPIIEKAELIKDHVDAINITDNQTSMTR
LCSLAACIRLKLLGLEPVLQMVTRDRNRIALQSDILGAASFDINNILCLSGDHQSFGDNP
KGQNVHDLDSIQLIQTVRHMRDEGKFLGGDDLDRPLAMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNLDKFEEWMKGVRDRGLHKKVHILAGLTPMKSVGMAKYMQKRVPG
MDVPDEIIKRLQGVEKGKAAEEGIKICVESIQRLKEVEGVAGFHVMAIEWEQKVPEIVEA
AGLYPRPSVN
>A0A8G0HNH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium glutamicum|TrEMBL
MSLTNIPASSQWAISDVLKRPSPGRVPFSVEFMPPRDDAAEERLYRAAEVFHDLGASFVS
VTYGAGGSTRERTSRIARRLAKQPLTTLVHLTLVNHTREEMKAILREYLELGLTNLLALR
GDPPGDPLGDWVSTDGGLNYASELIDLINSTPEFREFDLGIASFPEGHFRAKTLEEDTKY
TLAKLRGGAEYSITQMFFDVEDYLRLRDRLVAADPIHGAKPIIPGIMPITSLRSVRRQVE
LSGAQLPSQLEESLVRAANGNEEANKDEIRKVGIEYSTNMAERLIAEGAEDLHFMTLNFT
RATQEVLYNLGMAPAWGAEHGQDAVR
>A0A7C4IY50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKDESRLKRVLDQGGFAVTAECGPPKGADKDTVLRKAELLRGVVDAVNVTDNQTAIVRMS
SLAACTLLKSAGLDPVLQVAVRDRNRIALQSDILGASALGVRNILCLSGDHQSFGNQPQA
VGVFDLDSIQFVQVVRTMRDKGTILGGESLTKAPELFIGAAANPFGDPFSFRVTRLAKKV
AAGAEFIQTQCIYNLDRFEKWMAMARDKGLTEKTYILGGVTPLKSAGMAKYMKKKVAGMD
VPDEVIKRLEGVPANQQAEEGLRICVETIQRLKEIPGVRGVHIMAIEWEEKVREIVESAG
LMPRPVVSKQ
>A0A2N3H8W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. YY-1|TrEMBL
MSQQRRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTVNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNLEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRVFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLSIWNNLKLPR
>S0K631|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus columbae DSM 7374 = ATCC 51263|TrEMBL
MSEKSAHQPTLSFEIFPPNTKVGEEKLIQTLSELKGLTPKFISVTCSNRQHNIEQSTVRL
ADYVQNQLQIPAVAHLPALYLSKQQVNQILTALAQKGIDRVLALRGDKIAGVPTKGDFQY
ASDLVSYVKSKNQAFTISGACYPEVHPDSANRVEDVLHLKQKVEAGCTYLVSQLFFDNQS
FYQFQENCALAGINVPILAGIMPIVNRNQAIRLIQTSKTKVPAKFKAILEKYEHRPQALR
EAGLAYAIDQIVDLVTQNVDGIHLYTMNQAQTARDISQATQALFAS
>A0A347TNN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malaciobacter marinus|TrEMBL
MFETLIQKLQEDKYLTLETTPQHEPIMHNIIEKVKKFDLQNRVDGFSATDNPLAKLKYNA
LFASLRLQQEFKKPVIATMSMRDRNKIALQSDLLGANEFDVRAILALTGDPAKMSDQPHS
KGVFESNSSMLLKMIKSFNYGMDIAGRPFKIEPKQIYPFAVTNSYARSFTSLEKKMHNKI
QNGAMGIITQPVFDVNNAKKLLEIFENAKEDVVGNKKKAQLIFGIFPITKLRTALFLSAQ
VPGIHVPQDWVDKLELANQISEEEEYKVGMQLSKDLFYEIKKLHPKIHLMTANKFDLADE
ILA
>A0A3M5ARB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas coronafaciens pv. coronafaciens|TrEMBL
MSQDRRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDGKDDLRSLLAQYREAGIKRIVALRGDLPSGMGMASGELRHANDL
VTFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EEVITQMCERLLQDGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A4Q5KGC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliivibrio finisterrensis|TrEMBL
MAYSHASHLESLNQNIAELDGNINVSFEFFPPSSEKMEETLWNSIHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKEQTGLIAAPHLTCIDASRSELIDIANDYWANGIKDIVALRGD
IPAGGGAPEMYASDLVELLKSQHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQASRFAKMNNVKIPGWMAQQFE
GLDDDPVTRQMVGASHAIDMTRVLSREGVKDFHFYTLNRAEHTYALCHTLGVRPKG
>A0A3R7SE67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium TMED163|TrEMBL
MDSENSPFSIEFYPPRNAEGESRLDAVHAELAKLNPDYFSVTYGAGGSTKTGTSKLVMKY
QAAGSQVAPHLSFGGTDEQEVLELLQTYKEAGXKRIVALRGDIPSGSGAPMHYRYANELV
KFXRKETGDYYHIEVACYPETHPEAKNFSDDVAFFKQKVDAGANSAITQYFYNVDAYFRF
VDYCDSQGINVPIVPGVMPITNFDNLKRFSAKCGAXIPLWLGKRLEDFGDDVTGLKQFGQ
DVVTELCYDLLQGGAPGXHFYSMNLSKSVSQIWSELGLQDRNT
>A0A4S2SGX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. A1136|TrEMBL
MPPLPSHPGLREILARGERSFSFEFFPPKTDAGERALWSAIRRIEAFDPSFVSVTYGAGG
SSRDRTVQVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGIRDVLALRGDPPGD
PKGEWRAHPHGLAHARELVTLIRQLGDFTVGVAAFPERHPRSRSWDSDIRHFVAKCRAGA
DYAITQMFFRVDDYLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDASFPDELAR
RLEAARDNPADGHRIGVEYATAMSERLLAEGAPGLHYITLNKSTATVEIHRNIQTTRSAR
VLAAAR
>A0A840HVV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizorhapis suberifaciens|TrEMBL
MSTSVVTIVPENASAMRLMDDYSIEITVKDGSELAKAAPLMAPNTRISVTFLPKEDYQKR
LAAVAEVLRLGLRPVPHISARRIKSEVELETYLSELAKLGASEELFIVAGDPDVPDGPFE
DALTVIRSGLLQKYGVRRIGIGGYPEGHSKIGDDQLWQALRDKHAALTEQGIGVSILTQF
GFNTEPVFAWLKQLRSEGIDAPVRLGVPGPASATTLLRFAARCGVSASSSVLSKYGLSLT
KLMQPTGPDKYVLALAKGMRSDIYGDVGLHFYPFGGLIATAAWIRAFSAIGEL
>A0A5Y9BLT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICKNLKKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALADIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNTLALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLIKEELHA
>A0A1F7MV21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium RIFCSPHIGHO2_02_FULL_73_26|TrEMBL
MATRRDTPFREAMRSLLVFDGAMGSLLYERGVFVTQNFEQLNVTRPDIVLKIHDDYVAAG
AQVIETNTFGANRFRLDRHGLADQVRAFNVAGARLARQAAGETVWVGGSMGPSGLVPGVA
TQAELALVSATFAEQAAALVEGGADVLVLETFRHLAEIRLALEAAREAAPDTPVIASMTF
DPTGTVADGSTPEQVASTLRDLGADAIGVNCGDGPQLALAIAERLVRSGLPLCVQPNAGL
PRNVDGRLLYMATPEYFDVFLRRTVQLGATMIGGCCGTTPEHVRWMAKSARMLGDRRVEV
APAGAVATAEAFAGLAPTPLAERSAFAAKVAAGKFVVSVEVNPAPGVDPSKALEGAKMLI
DSGVDIVNVADGPRAMARMSNLAFCTLLLERHGIQPILHVCGRDRNLLGQIAHLLGAHAV
GIRNLVIITGDPPKVGDYPEATAVYDLDSIGLLHVAANANRGIDPAGKPLPGGKTSFLLA
TGFEPGAADLDREIRRLERKKAAGAELVMTQPVFQQDLLEMVLERIAHLELPVMVGVLPL
VSYKNAEFLHNEVPGMQIPEEIRERMRRTPGGEAARKEGVRIAREMLFAVRDRVQGAYLM
PPLGRYELALEVLEGLKA
>A0A150K2Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weizmannia coagulans|TrEMBL
MPPFLGGFFHIIQRECKNLNLLETLKNRILVADGAMGTLLYAYGADTCYESFNLTHPEDI
HAIHRAYIEAGASVIQTNTYSANYIKLAQYGLEEKVKDINKAAVRIAKEAANRDTFILGT
VGGIRGQRKTEATLAEIKRTFREQIFHLLNEGVDALLLETYFDAEELYTVVDIAKKEADV
PVIAQFSLIEPGVLQNGTPVRDAFKELENRGADVTGLNCRLGPHHMIQAFEEIPIPKRAF
LSAYPNASLLDYEEGRFTFTNNADYFKTCAEKLVEQGVRLIGGCCGTTPAHIKATAEGVQ
GLLPVTEKTVRPPKIEIAAAPAQYEPPLHEIVKKSRSVIVELDTPKTLNTARFFEGAKAL
HDAGIDALTMADNSLASPRISNTAIAAILKEKQGIRPLVHITCRDRNLIGLQSHLMGLAA
LGIDQVLAVTGDPSKIGDFPGATSVYDLSSMELIAMIKQFNDGISHSGKSLQRKTNFSVA
AAFNPNVRNLDKTVGRLERKIRHGADYFITQPVFSTEKIEQIHEATKHLDAPIYLGIMPL
TSYRNAVFLHNEVPGIKLTDEILAAMEKTNGDPAKAREESLAISRTLIDAALGYFNGIYL
ITPLERYELTVECTRYIHEKTAVQGAGIV
>A0A6J5IRJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia aenigmatica|TrEMBL
MSSLKQALNEGRFVCVLEVVPQQSPSRLTAFEQIVQRGHLAGWPLLPSFADRVGLHSDMS
PLEGAAALGNPASSLLHFSGKDRERADLLLQMESMKARGLEQLLLLSGDRLPGHHPGQAP
VRYLESVPALQIAREQCPDWLLGAALNPFKYREEEGGAQYLKAQKKLLAGADFFTLQLGF
DAAKHVEAQTWMRAQVRMKPMLACVMRLTDKRAAALQAVPGVVITESMRALLGREQQVSQ
AYASARSPERLALQIVGLQLMGYAGAHVSGLHTLDELLSLEQAITEQRDSVTSLTEWDER
WRASWQMPGVPQVCFAPETDAWEMGQSDVTATRRERLRHTLLSTAHSQLFGGTG
>A0A0C4US04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria luxurians|TrEMBL
AYGIHLGTEMCKKILAHGIKTVHLYTLNLEKSALAILANLGLIDMTKIKRPLPWRPPANV
>A0A7J6Z3R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Abscondita terminalis|TrEMBL
MKVTEHIAQSKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASYFKYLLGRSVFIWEFDNIMALRGDAMKGEKYFEPTKG
GNRYASDLVTQINDLGKGKFLHGEISGNDTNNSFCIGVAGYPEKHLEAPSMQYDLKMLKQ
KVELGADYVVTQMFLDNQKYFEFVKLAREAGIDVPIIPGIKPFAVKKHLQLLPQVFKIDI
PEDLVNAVSQCKNNEAVKPKSPPGEKKKKNFWKNWVGGCFSNARSY
>A0A4S3GSW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Akac8|TrEMBL
MALGTASTRTDRARTVRDMLATGKRTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADTTLTPVAHLTAVEHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNAVF
PDALKERILAAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A2E1U5N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MFSKRGPTASFEFFPPKNGEAWDALFAGISAFERLQPSFVSVTYGAGGSTRARTHDLVVR
LRSETSLLPMPHLTGRGHTKGEVESILVRYAESGVDNILALRGDPPQDGDPGPGDFPHAI
DLVRFIKAFNESGGHPNGGFAIGIAGYPEGHHETPNLLTEMDHFRAKVDAGADFAISQLF
FDNRRFLDWRDRCTMAGIQIPLVAGLMPITSASGMRRMAELAAGTLIPARLLRGVLDREA
DPEMVESFGVLWATEQSRDLLDHDVAGLHYYTLNRSRAARRVYETLGIRDSRSFMSGS
>A0A0T7A2D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. GL28|TrEMBL
MTAQTLYPAERGNLRLSFEYFPPKTDEMEVQLFQTAGDLSIFGPAFVTVTYGAGGSTKAR
SLTTVRRMVEEKGFANTAAHLTCVGAPKAEVDAVIDEYIDYGVRHFVALRGDPQGGIGSA
YQPHPDGYASSTDLVRAIRARGDDIEISVSSYPEKHPESPDVAADIDMLKRKVDAGANRA
LTQFFFDNNDFERYLERVRRAGINIPIVPGILPINNLAQVQKFAGLCGASVPEAIVTRLV
HLEDRPAERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLVTAVLDLVGFEQVALEAN
DALDEAPRTRAAGAAA
>A0A1B1ZH82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. HH130630-07|TrEMBL
MTTTSASTVTERISVDRPFFAVEFFPPRDDRGEAELWRAIRRLEVLDPAYVSVTYGAGGS
SRDRTVRTVERIATDTTLCSMAHLTAVSHSVDELRHVIGSLAAAGVRNIMALRGDPPGDP
LGEWVKHPDGLEYADELVSLIKRSGPFCVGVAAFPYGHPRSADVEADTERLVGKFRAGAE
FAVTQLFLEPDGFLRLRDRVAAAGFDQPVIPGIMPLTSEKTFHKGPELSGSPLPPALVER
LAPYSGDAAAFREAGMEVTGELCERLLAEGVPGIHFYCLNRSTATTELVDRLGLGTDRSG
ADGTAAASVLSA
>A0A1H4N6T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces misionensis|TrEMBL
MTTFSFEFFPPATAAGERALWSAVRKVEALRPDFVSVTYGAGGSSRDRTVALTRRIAAET
TLRPAAHLTAVGHSVAELRRIIGSYADAGIRDVLALRGDPPGDPRGPWVPHPDGFTHAYQ
LVELLRSLGDFTIGVAAFPEGHPRSPDARSDLRHFVAKCKAGADYAITQMFFRAEDYLRL
RDRVAAAGCETPIIPEIMPATDVRQIRRFAELSAATFPKDLAHRLEAARHDPAVAHRIGV
DHAVAMADRLLAEGAPGLHYITLNRSTAALDIHRTIQASRSLSVR
>A0A1N6PZX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas flexibilis|TrEMBL
MSQERRYSFEFFPPKTEVGHEKLLVTARRLAECRPDFFSCTYGAGGSTREGTLNTVLTLD
RQVGVPTAPHLSCVGDSKAELRALLNTYKEAGIRRIVALRGDLPSGMGLASGELRYANEL
VEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLKNFVRKAQAGADSAITQYFFNADSYFH
FVERAQKQGVDLPIVPGIMPITNYTSLARFSDACGAEIPRWVRKQLEAYGDDVASIQAFG
EQVVTEMCEKLLAGGAPGLHFYALNQAEPSLAIWNNLKLPR
>A0A544ZR10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbispora sp. KK1-11|TrEMBL
MALGLPSRLPDRVPTVRELLAAGERSFSFEFMPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPRGGNPLDEWVKHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSATIESDTRYFV
QKCRAGADYAITQMFFRAEDYLRLRDRVAAQGCDTPIIPGIMPVTQMSTIARSEQLSGAP
FPPEVAERFAAVADDPAAVRRLGIEHAVELCQKLLDEGAPGIHFITFNRSSATREVFQAL
HSVPAAVAG
>A0A4R0BZU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. viciae|TrEMBL
MMIAPQSESREKAPLADLLSHYSIEVTSRDLQSLESITATLPQGCEVFVAHLPKEDIGLL
VRASAGLRDAGFVPVPHIVARNISNRLELDTMLARLSEEAGVRNALVLGGDRDDAAGAFG
SSLDLINTGLFQTYGIGRIAIACYPEGHPRIASAVLDAALTAKVDAAARAGLDVLLVSQF
LFDPKPLLNFARRLRERGVTAPLSVGIAGPASRTKLLKYALRCGVGASLRALRERSEIAR
NVLSGETPEELLMEIAAAQTAEPDLGISGVHFFTFGDPAQSIRWAEQQVDR
>A0A2E5UH27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerae bacterium|TrEMBL
MRIDDILTXDKTLFSFEFFPPKTDXGWSALSVRLAAFEALEPSFVSVTYGAGGSTRDKTN
ALVKHLATETSLDPIPHLTCVGXSKDDIKELLTGYAEVGIDNLLALRGDKPQEGVTDSEF
RYGXDLVKHIKAFDGRSFGIGVAGYPEGHPETPNRLTQMDHLKAKVXAGADWICTQLFFD
NNAFYDWKERCEISGIXVPMLAGIMPITSLANMKRXAELAGGTNXPAALQRRLMRCQDDP
DAVRNVGISWAAEQCADLLDNNVRGIHFFTMNQSSATEEIYKSLGVTSSSKLR
>A0A660KVQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brockia lithotrophica|TrEMBL
MPFRILVEVPPPKSNVVGPFLANVDALAAMNVDAVTLSDNSLAQARMANVVAAQLVRQRV
NLPVVLHVNTRDRNLLAQQSLFFGLAALGIHDVLIISGDAMRLGDHPEGKAVYERTSIDL
MYLVRGMNEGRSFFGRPLKSPTSFRIGGALNPTSAGGFSRDRALRKVEAGATFFLTQPLF
DDRALEALDELRTVLPPGIELYPGFMPLTSEKNARFMASVPGFSVPEPLLRAYAERPEDP
EIGIEFLLELFERNKPFLSRFAGVYLVTPGRKVELLRPLVEYLRRQFSRE
>Q8PQJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis pv. citri (strain 306)|TrEMBL
MPSGASTITDTYSLEVSVKDIGALTNAAPRILPGSDMFIPYLPGQTEAARLAAAQRVRRL
GFEPVPHLSARRIGSLEELQAVIARLVGEADVTRCLVIAGDPSTPKGPFADSVSLIETGV
FERSGIRTIGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDADIVMTW
LEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGNAGPDR
FVDRLVSRLTEAHGDVRLHFFPFGGIAQSVEWVAHYRSCEASQDRVSSVAAD
>A0A418YDY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Motilimonas pumila|TrEMBL
MGSQSARNIEVLNQNIAELNGDINVSFEFFPPTSEAMENTLWQSIDHLKKLKPKFVSVTY
GANSGTRDRTHGVIKDIKERTGLIAAPHLTCIDASKDELKQIALDYWNSGIKHIVALRGD
IPEGGDRPHMYAADLVELLKSQASFDVSVAAYPEVHPEAKTAQADLLALKAKMDAGADRA
ITQFFFDIESYLRFRDRCAAIGIDQEVVPGILPVSNYKTLVKFSKLCNVKVPNWMHKMYE
GTDDDPTTRNLIGASIAMDMVKVLGEEGVKDFHFYTLNRSELSYAICHTLGIRP
>A0A0S8ACL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonas sp. SG8_17|TrEMBL
MNKLLSRLIADGQVHVMDGAMGTMLYSRGVFVNVCYDELNVKDPRLVQSVHEEYVRAGAE
IIETNTFGANPVKLSAFSLDTRTEEINRAAALVATAAAKGRASVVGAIGPLGIRIEPWGP
TARDEAVEFFQRQVSGLVEGGVDGFILETFADPEELHAALRAVRDISDLPVIAQMSFGED
GTTAYGTSVETAAQALTEWEADVIGLNCSVGPAAMLDAIERMVQVTNRPISALPNAGLPR
DVGNRQIYLAAPEYMARYARRMIEAGAKFVGGCCGTTPAHIEKITEFVAGAQPRVTSRYA
SRQDVAAPKGAEPPPLAARSHWGQKIARGDFVRSVEILPPRGWQPKGMLDKCRILQEAGL
DAVNILDSPRSRSRMGALPSGIIIKSELEIEPVVHYTCRDRNMLGMLSDLLGAAAAGLRN
LLIVTGDPPSMGTYDITGVFDIDSIGLTNVVFHLNHGLDPGGDAIGEPTQFVTGVAVNQS
AVDADRELRRFYWKVDAGAEFAVTQPVFDAGQLERFLKSIEQFNIPIIAGIWPLRSLRDA
EFLANEVPEVVVPDSVIARMARAQEKGHDFATAEGIRIAREVLGQIESSVQGVQVSGTSG
RVENALEVLEE
>A0A355X6M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MLNNNKVTVSFEVFPPKEWAKLADTKKVISEMVKDKPAFMSVTYGASGTTSGYTTEIANA
IRQGGVTPLSHLTCLTSTKEKINSVLDELEKNGVENVLALRGDIPKDFIMSKSQYYHHAY
ELVNEIKARNHFCIGGACYPEVHPESKNRVEDIAHLKEKVDCGLDFITTQMFFDNEKFYN
FREMCAIKEINVPIIAGIMPITNAKQIKRSAELSNASIPKKFEKIMERFGENPDVMKQAG
IIYATEQIIDLMANGVNNIHIYTMNKPDVAHQIMKGLSAIINEQG
>A0A060XH72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus mykiss|TrEMBL
MGADWEEEEAGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDA
GADFIITQLFFRADTFLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLQVPEEI
MQVIEPIKDNDAAIRNYGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWI
EDPRRTLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGEL
NDYYLFYLKSKSSKDALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPL
APETNLLKDELDKVNRRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSE
NVTALLKVLKKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSF
LYWKVRSKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVI
DDMFELLDNPPEEQPAEQPAEQPNDEQSDKEQPGK
>A0A0S2S9X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. IHB B 3084|TrEMBL
MKPDLRTVLDREIIVGDGAMGTFLYQLGFPVNTSYEELNITSPDVISDVHRQYVQAGARL
LETNTFSANDYKLARFGLESKVEEINRAGVRIARAAAGPEHYVVGAVGSICGGKRLNISK
VELARNYDQQIDALLSEGVDGILCETFYSLDEVRIALRGVRKYSNIPVICQFAVDQVGRT
QDGFSVAEAFTVLRNEGADILGFNCHSGPQGIMSVMEQLDGPLSVPLSVYPNAGLADYVD
GHYVYGASPEYFGECAASFVELGTRIIGGCCGTTPEHIAAISKALNGLQPPPLAPRDLLS
DAPVIVAEPEQIAREGERGNGRNASEPNIVELVKERHTVIVELDPPRDLDITRFMQGAQA
LKASGADALTLADNSLAVTRMSNMALGHLVSLETGLRPLIHIACRDRNLIGTQSHMMGFD
ALGIDHVLAVTGDPARFGDLPGASSVYDMTSFEIIRMIKQLNDGIAFSGKPLKQKANFVV
GAAFNPNVKHLGKAVQRLEKKIASGADYIMTQPVYDRELIISMAEQTRHLEVPIFIGIMP
LASGRNAEYLHNEVPGIQLSDKVRARMSGLEGAEGRAMGVTIAKELLDTAMEHFNGIYLM
TPFMFYEMTAELTSYVWQKSGRVQAPLFRL
>A0A2N9W2D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium zundukense|TrEMBL
MTKIAASIEVAARQAIESQDLPGLFPAGTRVYITDMGTDSVDTLTSAAKRVHDLGYKPVP
HFASRRLSTKAALETRIRRAAQEAGVTDVLIIGGGLERQAGEFSSTMEVLETSFFDKYGI
TEMGVAGHPEGSPEFSEAVAIEALRLKKNFGERTGAKLRVVTQFGFDADRFIRYAESLRE
HGVDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNALSLTALATSHSPEGVVGPIE
QHAIANPASAIKQIHIFPFGGLKKSSEWLVDRGSWTVHNASHASANAAAS
>A0A351ECF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
GIKEQLETYLAHGIDHMLALRGDIPEGDTAPQTFPHASDLINAIRREGADFCIGGACYPE
GHPESYNSDADIDGVRRKVESGCEFLTTQMFFDNNILYNYMFKLLRHDIRVPVIAGIMPV
TNAKQIKRIMSLSSSSMPTRFKAIVDRFANNPEAMKQAGIAYATEQIIDLIANDVTHIHI
YTMNRPDIAGSIMTNLSKIIDGYEAE
>A0A0P0MJ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. 103DPR2|TrEMBL
MKKLPVSFEFFPPKTPEGAEKLRAVRQQLYTQAPEFCSVTYGAGGSTQEGTFGTVGEILK
EGVAAASHFSCIGASEESVRKELATLKAMGVKRLVALRGDLPSGYGMGGAFHYASDLVAF
IRKETGDDFHIEVAAYPEVHPQAKSPESDLQAFVAKVKAGANSAITQYFYNTDAYFRFVD
DAHKLGVDVPVVPGIMPITSSTQLLRFSDACGAEIPRWIRLRLQGYGDDTASIKAFGLDV
VADLCDQLRNAGVPALHFYTMNQSATTLELLKRLA
>A0A349BN56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MKIARLLKNKRQIFSFEFFPPKTDEGEKRLFETIENLKELGPSFVSVTYGAGGSTRDKTA
GWVIRIKNELDIEAMAHLTCTGTSCENLKRILDKLQENGIENILALRGDKPQDTNSIAQM
PQCYNHTNELIQYIHDNYDFCIGAAAFPEGHTESPSLEKDTYYLNMKSMAGAEFFITQLF
FDNRLYFDLLDRASKIGINKPIIPGIMPITSADQVERFTSLCGATI
>A0A3E4XJP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus vestibularis|TrEMBL
MTSQTPSLSFEVFPPNPAIGNEKILRALEDMQGLAPHFISVTASNNKYNIKETTVPLADH
IQNDLDIPTIAHLPAIYLSKEKVADTLRDLDAVGVHRILALRGDIIPGVEPLKDFRYATD
LIEFIKEEAPQFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFRSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNAETARHIHEATHSLFKHHSQVSAL
>A0A353RDR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKLIQIIPQKRPSLSFEVFPPKNNGRYENLRSAIARIAELSPSYMSVTYGSGGGTSSTTV
SIAAALQKSYHVPVLAHLSCIQSTREGVRSQLDALRAAGIENILALRGDLPPGSEPQAGW
YYRFASELVREIRRYGGFCVGGACYPEGHPESRTQMEDIAHLKEKVEAGCDFLTTQMFFD
NNIYYNFVYKLREAGISVPVVAGIMPVTNLKQIRRILALTGTALPQRFRYILDRFGDNPA
AMKQAGIAYATGQIVDLFANGVPAVHVYSMNNPSVAGKIR
>A0A419GY49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospiraceae bacterium|TrEMBL
MNRKITDIFREKEKTFSLEFFPPKTPKGVEQLYRTADELNKLGPDFVSVTYGAGGSTRGA
TMEICAEIQKRFDIAVMHHLTCVGHSRSELKAILDQAKANNIRNILSLRGDPPKGVEIWE
PAPDGFEYCYQLNDFIRDNYGDFFSVGVAGFPEGHIHCPDKATDTKHLKIKIEHGGEFII
TQLFFDNTVYSEYLERLKNEGVQVRVIPGILPITSYEGLLKFCNTCGATVTQEVHDIFKL
LSGDEQATAEAGIDFAVRQCKDLLDRGAPGLHFFTLNKTEPVREIWKRLGIK
>A0A502VQ50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-8-4|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A1G4TP41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp. NFR10|TrEMBL
MKIPEHIANANGKTLFSFELIPPLKGQSIQGIYNAIDPLMEFKPPFIDVTTLREDFIYKQ
HPNGLLEKLSYRKRPGTIAICAAIMNRYKVDTVPHLLCGGFTKDETENALIELEFLGIEN
VLVLRGDARLGDSSFVPTPNGHCYATDLLQQVVNLNNGIYLHEDHGNTAKTNFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVEMGAQFIVTQMFFDIGKYKEFVNGCRANGINVPIIPGLK
PITSSKQLVTLSKTFHIDIPEDLSDAIHACATEKDVKEVGIEWMINQCKELIAFGAPVLH
FYTMSNAGPTKRIAEAIF
>A0A8B5JJY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus xylosus|TrEMBL
MSQLLDKLKSNILVADGAIGTILYSEGLDTCPEAYNLNHPDKVERIHRTYIEAGADIIQT
NTYGANFEKLKVFGLEHRVKDIHQAAVQIAKKAANGDTFILGTVGGFRGIKQEDLELSSI
QYHTEIQVETLVNAGVDGILFETYYDLQELTNIIKATKSKYDIPIIAQLTALNTNYLRDG
TEINQALQQVTASGADVVGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSQF
KYSDNASYFGKVAEQLINEGVRLIGGCCGTTPEHIQYIKSSVAGLNPVTKKDVIPITKYI
NNTEKEPKKQNLKSKVENRPTIIVELDTPKHLDTETFFRNIKKLDDAKIDAVTLADNSLA
TVRISNVAAASIIKQRYDIEPLVHITCRDRNLIGLQSHLLGLSLLDINEILTITGDPSKI
GHLPGATNVYDVNSKGLTEIALRFNQGINTDGDALKTKTNFNIAGAFDPNVRKLDGAVRR
LEKKLESGMHYFITQPVYSKEKIKEVYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSETILEQFEAVKDDKAKTKALSLKLSKELIDTVHEYFNGLYLITPFQKVDYTLELANY
SKTITLTKQEAIL
>A0A6I4UL54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter ramosus|TrEMBL
MMTPTLDQLHEYRTATDMPLFSGLPGDVAVSFEFFPPKSEKMEEQLWDAVTQLKPLGPSF
VSVTYGAGGSTRERTHATVARIIGEAKLPAAAHLTCVAASKAEIREVAEHYWEAGVRHIV
ALRGDAGEPGAPFTPHPEGYASAAELVSGLKAIAPFEISVAAYPETHPDALSPQDDIDNL
KRKLDAGATRAISQFFFSPEAFFRFRDACAASGIDAPILPGILPVTNVAQARKFAAACGA
SIPAWMDGLFEGLDEKPAARQLVAATVAAELCRRLYAGGVRDFHFYTLNRPELAYAICHM
LGKRPVGDDA
>A0AJD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / CIP 8149 / NCTC 11857 / SLCC 5334 / V8)|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGKKLPDALEELITLGADVVGINCRLGPYHMARALETVPLYEKAYLAVYPNASLPEMQD
GKVIYQSDTDYFAHYGEVFRQEGARIIGGCCGTTPDHIRALRQGLETTKPILEKEVRPIL
ELVPEEVVDEEAGERLLDKVKERLTILVELDPPRTFDTTKFFEGAEALNNAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNALNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTEEVRERMREAEEHGYANEEGMAIARELIDAICEHFQGIYIITPFLRYDLSV
ELAKYIQKKQQVEIISK
>A0A8C9RKN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Scleropages formosus|TrEMBL
MVNQVQRMDGGSQAPKSDSSGASNSGGESSKESSRCSTPLLDADRADRLREKMKRRIESG
DRWFSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKDQITAHLAKAKRLGLKNIMALRGDPLADVWEEEECGFNYAT
DLVKHIRWEFGDYFDICVAGYPTGHPEAESYEADLKYLKEKVDAGADFVITQLFFRAETF
LKFVKDCRAVGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEAMMQVIEPIKDNDAAIRN
YGIQQAVDMCKVLLQSGDVPGLHFYTLNREVATMEVLKQLGLWNEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LVKMWGEELMSEESVFEVFTNYITTQPNRNGHKVMCLPWNDDPLAPETNLLKGELEKVNR
RGVLTINSQPNINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRV
NYHIVNVQGKNITNAPEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFGLWIEQWA
KLYEDESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVIDDMFDLLDAPPQSLIT
>A0A7S9YYF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. Cam5-1|TrEMBL
MAGAATIHPNWEQHIPKRITDGYSIEMTAKDCDALRAAASMLAPETPIAITFLPGETIDA
RIDAAKLVRDLGFEPMSHLSARRIGSFEELEQTVRRSAEEAGVRRMFLVAGDPPVPAGPF
EDALSLLRTGLFEKNGVKAIGIAGHPEGHPVMNEEARWSALLAKCAEVSDRGMAPLIVTQ
FGFDATPVLDWLIELRRRGIDAPVRIGVPGPAGIKTLLRFAAHCGVGASASVLAKYGISL
SRLLGAAGPDRLVGDIAAGLHSGHGPVRLHFYPFGGLARTAEWIGQHRSNQN
>A0A4Y8SD17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter psychrotolerans|TrEMBL
MKITEHIANANGKTLFSFELIPPLKGESIQGIYNAIDPLMEFKPPFIDVTSLREDYIYKQ
HETGLLEKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLQFLGIEN
VLVLRGDARRGDASFVPTPNGHCYATDLLQQVVNMNKGIYLHENHEGILKTDFCMGVAGY
PEKHFEAPNMKTDFKYLKQKVDMGAGFIVTQMFFDNKKYFDFVNNCRANGINVPIIPGLK
PITTSKQLVNLSKTFHIDIPEDLSDAIQGAKAEKDVKDIGIEWMINQCKELVKFGAPVLH
FYTMGNPGPTKKIAEAIF
>A0A4P8IUA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. DHOD12|TrEMBL
MKPIEISFEFFPPKTQEGIDKLRATRKELALLKPKFVSVTFGAGGSTQQGTLDTVLDMAA
DGLEAAPHLSCIGSSKESLRAILNQYRSNGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFWIEVAGYPEYHPQSRSPKHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVARRLESFGDDREAIRAFGLDV
VTGLCQRLVDQGVPGIHFYTLNAATATKAICERLGV
>A0A3D8T0U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coleophoma crateriformis|TrEMBL
MHIKDMLSEAERSGQPTFSFEFFPPKTAQGVQNLYDRMDKMHGLGPSFIDITWGAGGNLA
QLTCEMVSVAQSQYGLETCMHLTCTDMGKEKVDDALQNAYKAGCTNILALRGDPPREREK
WVATEGGFQYAKDLVNHIRQTYGNHFDIGVAGYPEGCDDQDDPELLLDHLKEKVDAGATF
IVTQMFYDADNFTEWVGKVRARGITIPIIPGIMPISTYASFLRRCNHMGCKVPPKWSEAL
EAVKNDDAAVRNIGKGLVAELCRKILGAGIHHLHFYTMNLAQATRMLLEELELLPSQDRP
LKQALPWRQSLGLGRREEDVRPIFWRNRNKSYVVRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLRGTNEQNRKLWGEPASIKDIADIFLRYLNNDVESLPWSEAPISSEADVIKEDLID
LNKRGLLTINSQPAVDGVKSSHPVYGWGPKNGYVYQKAYLELLVSPALMEELIERIERNP
DLTYYAVNKSGILKTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAYRLGLDW
AHCFDADTPSRGLIENMMDSWSLVNIVHNDFHQTHGLFHLFDGLAVPDIGTPFQHVNGVK
AHINVVSNTEPVQKRLMIYDSTYEVKSSFNTLGNGIASSVVFWANFSTGLAFIYDLNDLE
AAAWKTDEKHFSYFWYFVRSALGGDFAWYRAFNGEALERQLNGPFGTQNRHLL
>A0A5R8P4K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea sp. KC401|TrEMBL
MSGLRAAFEAGRFAVTAEIGPPGGADAEAVTRKAELLQGWVDAANVTDNQGANVRMSSLA
GSVLAQRAGVEPVMQLTCRDRNRMALQSDLLAAGALGIPNVLLLTGDHPRFGDHPEAKPV
FDLDGVQLVWTARTLRDDGVLLSGKAVPARPAWLIGTVENPFAPPPRFRARRLAKKVSAG
AEFVQTQYVFDFEVFERWMADLRELGVTDHCKVIAGVGPIRSLRALDYMRTAVPGVHVPD
EVDRRLRGVPAGRVAEEGIRMCVEAVQRLATIPGVAGVHLMALGFEHGVPDILRRAGIPR
PPAALPDHHRHPMEGIGHAR
>A0A1I1G786|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides terrae|TrEMBL
MTESDAQHIGRLIREGGRSFSFEFYPPKDEAGEEQLWAAIEALGPYRPTFVSVTYGAGGS
TRDKTVRITARIARDTAMIPMAHLTCVGHTVAEIEAILDDYEAAGVRNIMALRGDPSDGP
RAAWTPTDGGFSYASELVELVRGRGTFDIGVAAFPEGHPSSASLEADADVLVAKARAGAA
FAVTQMFFRAEDYFDLVDRVRARGVDMPILPGIMPILNLGAIRRQGELIGTSVPQEIADR
IQARADDPAAVRAEGIALAAELCETLLAGGAPGLHFYTLNRSKATLEIFDRLNLTV
>A0A509CR12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella sp. NCTC 6947|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>G6ADJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella histicola F0411|TrEMBL
MDIKTLLNDGTTERRFSFEVLPPLKGNGTASLFRNIDQLKEFNPQFINITTHHSEFVYHE
REDGLLERQSIRRRPGTIAIAAAIQQRYGIPVIPHVICSGATKEDIEYELLDLQFLGIDT
LMLLRGDKAREDRQFTPTKGGHRHTTDLIEQVKLFNDGKFIDGSEMKHPGNPFTYGVACY
PEKHEEAPNIEQDLQYLKKKQELGASFAVTQLFYDNQKFYDFLQRARNMGITIPIVPGIK
PFAKLSQLNIVPKTFHCDIPEELAGLARLCKNDDEARELGIEWATRQVKDLYAHGINNVH
FYTVSAVNSVHEVVRRLL
>A0A4R3Z7F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Longibaculum muris|TrEMBL
MKISEILKNKATISFEVFPPKNKTGDISSIYYTIDELAKLQPDFISVTYGAGGSTKGKTV
EIASKIKNDYHIEAVAHLTCISSTSQEVLDICQQLKEHNIENIYH
>A0A6B3L9P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuriroseicoccus oceanibius|TrEMBL
MHISDILSEGRPSFSFEFFPPGTPEALERLYTTMRELEELNPAFVSVTYGAGGSTRELTH
ELVVRLKETTTLDPIPHLTCVCHSEEEISSIVENYAKAGVSNLLALGGDPPRSMPNYDRS
QDAFRYASDLVKFIREREQSGALVANGGRGFGIGVAGFPEGHPATPNRLLEMDYLKAKVD
AGADYICTQLFFDNHAFLDFRDRCRLAGINVPIIAGIMPVTALGGMRRMAELSGGTCFPA
KLLKALARGGDDPEAIRRIGVHYATQQCADLLDNDVDGIHFYTLNRSDATREIYRSLGID
SSVAAPAGDGI
>A0A6J5A0M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter insuavis|TrEMBL
MSSLKQALGERRFACVLEIIPQHAPARQAALQRIVRRGRLAGWPLLPAFADRVGLHSDLS
PLQGAGALGDPASSLLHFSGKDRARADLLRQMDAMQARGLSQLLLLSGDRLPGHDPGRAP
VRYLESVPALQIARERGPDWLLGAALNPFKYREEEGAAQYLKAQKKLLAGADFLTLQLGF
DAAKHLEAQAWMRAQGRVKPMLACVMQLTHRRAAALQDVPGIVITDAMRELLGREQQISP
AHASARSLERLALQIVGLQWMGYAGVHLSGVHTLDELLLLEQAIAEQRDAVTSLSDWAQR
WQASWRMPGMPQAGFAPDIDTWELGQSDVAATPGERLRYALLSTVHEQLFNRTGWLGSAF
GWSVTRPFWKTGVAAQALHAVERTLKRPLVGCDTCGTCRLQDTLYVCPETCPKGLANGPC
GGTRLNRCEFGDRECVHSVKYRIAKSADQLPALAQTLIPGIEAGDRHRSSWPEWFKPEDP
TPGNDCQSLPKSG
>A0A7C7AXY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas vasicola pv. zeae|TrEMBL
MMSTDTPSLANTIADAYSLEVSVKDIGALTKAAPRMLPGSTMFIPYLPGQNDAARLAAAQ
MVRGLGFEPMPHLSARRMTSLDELQAFVARLVDEAGVTRCFVIAGDPSTPKGPFADSLSL
IDTGVFERAGIRTIGVAGHPEGHPIMHTAEQWDVLERKCRSIEERGMAAVIVTQFGFDAD
MVVTWVEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSKYGISIGKLFGN
AGPDRFVDRLVSCLTEAHGDIRLHVFPFGGIAQSVEWVAHYRSRNAPQDRISAVRADRP
>A0A6B8VQ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium kalinowskii|TrEMBL
MAQTRQIPISSLLSNSTDVMFSVEFMPPRDDAAEQRLWNAATTFKDLGAAFGSVTYGAGG
STRERTFRIAQRLTELPLNTLVHLTLVEHSHAELVSILEDYASAGLTNLLALRGDPPGDP
LGEWMKAPDGLEYTSELIELVRATDHSRDFDLGIAAFPEGHHRAESLELDTAYTLAKLRA
GAEYAITQVFFDVEHFLRLRDRLAAADPVAGAKPIIPGIMPITSLRSVQRQIELSGATMN
PEVGERLERAALSGDAAVREEGIRISTELAERLIAEGAPDLHFMTMNFAKATHQVLHNLG
MAPQWS
>A0A6I1FYL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetrasphaera sp. F2B08|TrEMBL
MATGLPSRLERPTHVTASIPANLAAPPASISFEFFPPKDDASEAALWQAIRRLEAVRPAF
VSVTYGAGGSTQDRTVRVTERISRETTLTPLAHLTCVGASVGSLRRVVGQYASAGVRNVL
ALRGDPPGDVRGQWVAHPGGLDHADQLVALVRSLGDFTVGVAAFPDVHPESPDLDHDVEV
LVRKADAGATFAVTQMVFDADAYLRLRDRVAERRDLPVTPGLMPVTNLRQIARMSELMGT
PLPAPVLDRLTAVADDADAVRAVGVQIATELAERMLAEGAPGIHFITMNRSTATLEVYRN
LSL
>F6B710|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotomaculum nigrificans (strain DSM 14880 / VKM B-2319 / CO-1-SRB)|TrEMBL
MTVQISKLYQQKKPVISFEIFPPKSTSPLETVFTTLDQLVRLKPDFISVTYGAGGSSRDR
TKEIASRIKNQYHIETLAHLTCVGHSSAEIDQIIKDLLAENIENVLALRGDPPANQPDFD
FSKCEFSYAADLIRHIKAKTNICVAAAAYPEGHASCKRLSEDLNWLKYKVDQGVDFLITQ
LYFDNRIFYNFIENARRIGIQCPVAAGIMPVLNAKQIKRIISLCGASMPAKLLMLVDKFG
DNNEDMEKAGLEYASEQVRDLLESGVEGIHLYTMNKPQQITQILKNVGLA
>A0A838YAW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquitalea magnusonii|TrEMBL
MNEPKKTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGHAAAPHLSCIGSTRENISAILNEYRNHGIRHIVALRGDMPSGMVAAGEFRYANELV
EFIRSEHGDHFHIEVAAYPEFHPQSKSAEDDLNNFVRKVKAGANSAMTQYFFNADAYFRF
VDEAQARGVDIPIVPGIMPIANFGQLCRFSDMCGAEVPRWLRQRMQSYYDDTASIRALGL
DVVTELCDRLLANGAPGLHFYTLNQAGLVSTVWQRLGL
>A0A5C4WZD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sediminis|TrEMBL
MSQSTLRRLLSTARYEVLPTAGIVERIEEYVAPGREITVTASTGLTLEATLSTAEQLQAL
GFRAVPHLAARMIHGRPELTEIVDRLAEAAVDRIFVPAGDATPPAGGYVGAHDLLVDLSS
MAAPFQHIGVSAYPESHPIIPDDVTIQAMWDKRDYATHLVSNLCFDPALIASWVPRVRAR
GVELPLVLGIAGKVELAKLARVATKIGVGESTRFLRKNTATFTRMAKPGGYNPRKFLDKI
GPVLDDPEMGVAGLHIYTFNQIKDTEVWRRKQLAALGGAEEVSTAW
>A0A7Y6AHT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. C9C5|TrEMBL
MSPPSLIDAHPNLAGAAPVALSYELFPPRSPAAAESLWTTIGELEATSPDYVSVTYGASG
SNRNTAVELINRLVQETTLRPLAHLTCVGNTPQELAEIIGELLDVGVRGILALRGDQPKD
GGAPADGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYAQLLSRARRAGVTIPIVPGVMPLTSIRRLTRLGELTGVE
PAPELIERLAAADTDAERNRIGVSATVDLANAALDAGAPGLHLYTFNEHASALEVLDKLA
LPRPRSGNRHSSHQRPAGRRQLAS
>A0A7C7AWV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas vasicola pv. zeae|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
SALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A098T7Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea sp. BAL378|TrEMBL
MNSSSRASAQDSAERIKVSFEFFPPKNGDMESQLWESITRLAPFQPDFVSVTYGAGGSTK
QPTLNTVARICAETALAPAAHLTCVGSDKAAVDAVAREFQAVGVNHFVALRGDPPEGVGA
AYQPHPGGYANGAELVAGLRALSDFEISVSAYPERHPESPDFATDIDMLKRKVDAGATRA
ITQFFFDNDIYERYVERVRRAGIYVPIVPGILPIHNFGQVARFSKLCGASIPDWLARRFD
GLEKDPETRALVASAVAAEQVNDLVERGIDDFHFYTMNRAQLVYAICHMLGLRGADAASV
GAAA
>A0A1F6QFX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Margulisbacteria bacterium GWF2_35_9|TrEMBL
MQLSEIISSDKFFRSIEMFPPKQDETIPNIIDDINQLKPYDLAYISVTYGAGGSTQGRSL
KLIEGLAKQFDIMAHFTCVNTTRSQIDAFMGKLRALGVHNILALRGDIPAGMTKDEVLSD
FHYASELVKYLKETTKMDIAVAAYPEIHPESPTPEQCYDALILKANQGAELLITQLFFDN
DIFKRFFETLHKKGLQIPVIPGIMPITNFNGIKKIIELSNTKLPETLNNKLTKHKDDSDA
VFEIGMEYALKQSRDLKLFGVKGIHFYSLNKRKNVEPLLKEI
>A0A498BTS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium telephonicum|TrEMBL
MTAPLPLRDATQRCPKSMVYGPCGGVTLDGGCEVPGIRCSFVDHAAALNGLAFSPDDVQA
PAAAYDSGDMLHARPRTAAADEFAVLVEAGGVITADLPIRSADPAVITEAGARLRELTAV
IAGEPPGLRDALSPTHKALLLTTAGSRVLAGLTCRDRNRVALEGELAALADLGVSGVLAV
TGDHPASTALPQARPVFDLDATRLAALARRAGLFVAVAEQPTAPPVEYRPARLAVKARAG
AELGILNLCGDISAITRFTAAVAATAAPIPVLASVPVVISAAAARRLAALPGAALPADIV
AAVTSADDPVEAGIRSAVAWARRALTIPGVAGIHLSAISDHGTAGADASGLAAVDAVATT
AARLRAGIGSRADEAGAA
>A0A1C3EIB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterovibrio pacificus|TrEMBL
MALSLKEKIEDPAQGVYLIGTTPPKKGTDKAKIAEIAQKLLNRLHEIEYDGVVVYDIQDE
SSRTAAPRPFPFKHTVDPREYSQLVKHISKQDVITYKSVAQRGEQEFIDWLSETKEIYQL
DNLVLVGSPSSEGDIKLSLSDAYKVLEKHQQDFFLGGVTIAERHSSKRNEHQRLMKKTEQ
GCEFYISQAVYDAQATVNLITSYARTCRQEGIEPGRIILTFTPCGSEKTLEFMEWLGISV
PEATKWRILDAENPLNESVRICRENLNLILQSCASLNVPLGLNIESLTNRKEEIDASINL
YRLLKATMELSLAEKLLAS
>A0A503XD84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-3-4|TrEMBL
MTGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHDEITETQVDMVK
TAH
>A0A4R6LYD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enemella evansiae|TrEMBL
MSRRDPSIAELLAASDRPLFSFEFFPPASEEAARTLWQTVRQLEPLAPDFVSVTYGANGS
TRDRTINVTRQIARETTLRTMGHLTCVSQSRDDIRRVVGAYADAGIRHILAVRGDPPGGP
TAPWQAHPDGLRNATELVELIASLGDFCVGVAAFPDVHPEHHDPELDARILVDKANAGAD
FAITQLFFTARSYFELVDRVRSLGCDIPIIPGIMPVTNLRQIERFAELSGAALPTGVTDR
LLAADGPDAVRAEGVRIGTELADELLAGGVPGLHFFTQNRSRASREIHSRLQRVPA
>A0A1G8K5B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrimonas sediminum|TrEMBL
MGFHHAQQLEALNERLSHLKDIQVSFEFFPPSSESMEQTLWQSIERLQPLKPRFVSVTYG
ANSGVRDRTHKVIEKIHTETDLVAAPHLTLVDASDEELRALARQYWQQGVRHIVALRGDL
PEGQGRPNRFASDLVSLLKQEHDFEISVAAYPEVHPEARNAQADLINLKRKVDAGANRAI
TQFFFDIEAYLRFRDRCAAANIDVEIVPGILPVTNYRQLLKFSEFAKVHVPNWLHHMFDG
LDEDPATRKLVGANVAIEMAKVLAKEGVKEFHFYTLNRAELSYAICHALGVRPTP
>A0A8G0SS90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. S07E 245|TrEMBL
MSEERRYSFEFFPTKTEAGHEKLMAVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLE
HEVKVAAAPHLSCVGDSKADLRGLLSEYRAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQAQNFEADLSNFVRKVKAGADSAITQYFFNADSYFY
FVERVQKMGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSASIQAFG
EEVISNMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7Y5USS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
CTPSTEQGLDRMRDRIRALAQMADAINVTSNHAGVPRVAALSLARCVGEYQGEAILHLCG
RDLDPRSYLDALVGLSANEVHNVLCLTGDWPARAEPSAGNRTPPRTAHYFPLEAAQMIYE
ASHLRQFGASALADLNARPAPRSRTRECATRATARSSRSSSRRRRSRGSTTPTGSTTAAR
AGGSRSTRPRSPTRPAPTSSSSTAPGTG
>A0A8F9PEE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paeniclostridium sordellii|TrEMBL
MSLLKEALESGKFAVTAEMAPPKGTDLSHLIKCARAVKGRVHAVNVTDFQSAVMRTTSLT
TCKLLKDEGLEPVLQVTGRDRNRIAIQGELLSAGVFGIKNMLALTGDHTIVGDHPQAKPV
FDLDCVGILKTAQKLSQGTDMVGNQLKGAPKFYLGASVTPRYTPIEVQLLKMKKKINAGA
EFFQTQAVYDIDTMRYFRSHTKDMNTKVLAGIIPLKSPGMAKFMNANVPGIYVPEELIDR
LKSVGKENWVNEGIKIAGELIKQLKEEDLCDGIHIMAIGAEENIPAILDAANI
>A0A7Z9LY67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MASLVSFYTADRTGLSFELFPPKTEKGDAALLKHVARLSEFKPDYVTCTYGAGGSTRGKT
LDIVSAVKQQFNVPVASHLTCVASTREDLRQYLNDAERRDIDFIVALRGDPPQGATTFEA
VEGGLQYANELVELINGEFPNLGIAVAGYPEVHQEAPSADIDLDNLKRKVDCGADIVITQ
LFYRTEDYFDFCDRCVVAGITVPIVPGILPVINLAQIQRITSMCGAKLPQAFVDRLGEHC
DDDDWQFKVGVEFATAQVSELLATGAPGVHFYVLNKSQVTAEVLTQVGWSCE
>A0A0D2S0T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium raimondii|TrEMBL
MVFSLCTEAHPDAIGSNGVATPEAYQSDLAYLKKKVDAGADLIVTQLFYDTDIFLKFVND
CRQIGITCPIVPGIMPINNYKGFVRMTGFCKTKIPDEVTAALEPIKDNDEAVKSYGIHLG
TEMCRKILAHGIKTLHLYTLNMEKSALAILMNLGLIEESKISRSLPWRRPANVFRVKEDV
RPIFWANRPKSYLSRTIGWDQYPQGRWGDSRNPSYGALSDYQFMRPRARDKKLQEEWATP
LKSIDDIQEKFKNHCLGKLRSSPWSELDGLQPETKIIHEQLGKINLKGFLTINSQPAVNG
ERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKLDALVKKCNSFSSLTYVAVNKKGNLLSNI
GLTDVNAVTWGVFPAKEIIQPTVVDPASFMVWKDEAFEIWSRSWSALYPDGDPSKNLLEE
IQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A416R286|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoflavonifractor sp. AF19-9AC|TrEMBL
MKLAQLFGQGKTVFSCEVFPPKRDMPIDSIYTTLDGLKDIHPDFISVTYGAGGSKVNQTT
REIASIIENKYHIPAMAHLTCVGADKNDVDQLLADLKADGVENILALRGDVNPDVPPKTD
FAHASDLVTYIRSHSDFGVSAACYPEGHLESPDMVSDIRHLKEKVDAGAQHLVSQLFFDN
EDFFRFLERCRIAGINVPIEAGIMPVLSQASIQRMVSMCGASMPSKLTRILARYGDHPDA
LREAGIAYAIDQISDLIAGGVDGIHLYTMNNPAVAQQIAGSISSIRRV
>J7Q974|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystis sp. (strain SC2)|TrEMBL
MFNALHPTASPNQFAISYEFFPPKTPEMETQLWQTINRLAALKPHFVSVTYGAGGTTRER
THSIVARIVRETEMKPAAHLTCVSAAREDVDAILRDYWDAGVRHIVALRGDPPTGVGSHF
EAHPRGYANSTDLVRGIRRIGDFEISVSTYPEGHPESASIEQDLDALQAKVDAGATRAIT
QFFFDNDVYFKFLDKARGRGITIPIVPGIMPIRNFKQVAGFAQKAGASVPRWLAERFDGL
DEDPETRALIAATTAVEQVMSLARAGVNEFHFYTNNRADLVFAICHLLGVRPVRERAIA
>A0A2E3DHQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MASVAQFYTADHKGLSFELFPPKTEKGGAALMRHTEALMQFSPDYITCTYGAGGSTQTKT
MDVITQVKSAFDIPVASHLTCVGSTENDLRRYLQNASQQNIDFLVALRGDPPQGDTEFKA
VEGGFSYANELVEFIRAEFPDFGIAVAGYPEVHQEAISAESDLENLKRKVDAGADIVITQ
LFYDNKDYFDFCDRCIAAGISIPIVPGVLPVTSLTQIQRITSLCGSKLPGSFVQRLGEKG
ESNTEWQFEVGVEFAAAQVQNLVANGAPGVHFYVLNKSQATLCVLESIGW
>A0A429YVB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquibium carbonis|TrEMBL
MAFFKQASPETPAAGSEALLGSFVEGYSIEIMPRTAAKIDDFKALLPGGTRVYIAHIEGT
PIEEMVETAARLSGDGYPVMPHFPARIIRDKAMLEDWILRYRDVGVNQALLLAGGVTNPH
GELTSSMDLMESGLFDKHGYKRLHVAGHPEGNKDIDADGFYKQVDSALQWKQAFSERTDA
AMAIATQFAFEAQPVIDWANRLKAAGIALPIHVGIAGPAKLQTLIKFAMACGVGPSIRVL
QRRAMDIRKLVMPYEPTDVLTDLAAHKAANPGSLIEQVHFFPLGGIKASTEWANETVRTG
ALRKTG
>W8FUT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassolituus oleivorans R6-15|TrEMBL
MGSRLQEDFQNIHQGVYFVGTTPPKDSTTNERVDEIAEKLLERLSALDYDGMIVYDIQDE
SSRTNKPRPFPFMQTFDPCAYSRIIREKSGHPVITYKSVAQRNASDFSDWLTRAWNEFGV
RDIVLVGAPSSEGDIRLSLPEAYKVLATHEAPYHLGGVTIAERHAAKGNEHTRLLNKGKQ
GCTFFISQAVYDADATIDLLTSYAKSCAEQGVEPQRIILTFTPCGSLKTLEFMEWLGISV
PESTRQEMMAAEDPLAESIKICHNNLQHILAECLPLNLPLGLNIESLTNRKTEIDASIEL
FTLLKKTLDTGLEERRKAS
>A0A087ND66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. ba1|TrEMBL
MTLNDPAAPLYADLAGDCQVSFEFFPPKSEKMEAQLWSAIETLTPLAPKFVSVTYGAGGS
TRERTHNTVARIAKETPLAAAAHLTCVGASKDEIGEIADAYWDAGVRHIVALRGDPPEVG
GTFEPHPQGYKGAAELVEGLIKRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGAIR
AITQFFFTPDAYFRFLDKVLAAGITADIVPGIMPVSNFAATQRMAAMCNTQVPSWMARLF
EGLDDHPASRQLVSATIAAELCQKLYAGGVRDFHFYTLNRSELSFAICHLLGLRAKATAD
A
>A0A512HQP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium flavum|TrEMBL
MPATDDAAHHDPILQALAADRPAVSFEFFPPKDDEGEAQLWRTIDDLAPLEPTFVSVTYG
AGGTSQDRTVRITERIAREASMPPVGHLTLVGQSRGEIETVLKQYVAAGVQHVLALRGDP
AGGPRAPWEAHPDGMSHAIELVELVHQVGGLSVGVAAFPEGHPDCGGLDADADVLVAKAQ
AGASFAISQLFFRADDYFGLVRRVRDRGCDLPIIPGIMPILNLKQVARMAELSGADMPRE
VLDQIEPLAEDRAAVRAKGIELATQLCRDLLAGGAPGLHFMTLNRSPATREIFEQLRADD
LV
>A0A060DQQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum brasilense|TrEMBL
MTAPLSAPPSISFEFFPPKTETMEQGLWQSIRRLAPLAPSFVSVTHGAGGSTRERTHATV
CRIQDETGLPAAAHVTCIGATRDEIDAIAHSYWNAGIRHLVALRGDPSDMPGGGRCEPSP
GGYAYAADLVTGMRRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQFFF
DNDVYFRFLDRCAAAGIHVPVIPGILPITNVARAVEFAAKCGASMPARLVETFEGLDDDP
ETRRLVAATVAAEQCQALQAQGVRDFHLHTLNRSDITLATCHMLGIRAAVPVP
>A0A351FZY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
NELVTLIRDEFPDFGIAVAAYPEVHHEAPNADVDLQNLQRKIDCGADIAITQLFYENQDF
FTFRERYEGLGISAPLVPGILPVTNLAQIQRITSLCGAQLPDTFVQRLAEHEDDDEWQFQ
VGVEFATAQVRELLDQGVPGIHFYVLNKSQATSAVLQGLEWSRVNVA
>A0A1V3NLC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus casseliflavus|TrEMBL
MIRKRISPTLSFEVFPPNSKVGTKKLIHTLDAFKELSPSFISVTCNNSTRNIENTTVHLS
GYIKQELGIPSVAHLPATYLTKGRVLTILKQLDKLGVNHLLALRGDEQPTMEPCNDFKYA
SDLITFIKEQAPHFYISGACYPEIHPDSKSKVEDIHYLKKKTEAGCNNLISQLFFDNEIF
YQFQENCALANINRPILAGIMPIVNRSQALRLFKTSGTYLPKKFLRILDRYEHHPEALRD
AGLAYAVDQIVELVTQNVDGIHLYTMNNSATANYIYQTTSSLFKTQEELLSI
>A0A5I0BLB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Koketime|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A383TB44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus shcherbakoviae|TrEMBL
MKIRDMISKGEPTVSFEIFPPKSSYALETVFDTLGELKDLHPDFISVTYGAGGTAQSNTV
EIASRIKKDFGIESIAHLTGCTSTKEGMKRTLASIKDSGIENILALRGDIPQEKLTDKNW
NPEYRYASELIDDIKAAGDFSIGAACYPEGHVDSINKVDDLKNLKKKMDHGADFMITQLF
YDNDLFYQFKEKLDLVGIEQPVIAGILPVLNIKQVKRIQEISGCNLPPKFLRILDRYEHD
PASLQEAGIAYAVDQIIDLLSSGVDGVHIYTMNKPDATRRIMENISCVRKAVCRKEPQR
>A0A2V6ULD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
IHSEYIAAGADCIETNTFGANRFKLAVHGLGSQVREINLRGVKLARDVREAMGRDVLVLG
SMGPLGKYLAPLGTLGEGEARDAFREQAEGLLEGGVDAFVVETMSDLGEVALAVEAIRAV
ADLPIVAEVAFTDEGLTFLGRTPAEVARTLSALAVQVVGANCSVGSSTLYEVLEQMRPAA
GGRPIAIQPNAGLPSRVGERLIYLSSPAYMADYAARMLAAGARVVGGCCGTTPEHIRAMR
AVTGPTPSARAVGRAAAPAAARPDQAPVLRAAAPPTRLERKLAAGEFVVTVELDPPRGHN
IEKLVQGAKLLKERGAEIVDINDGSLGRIRMAVLPTAVLVRDATGLEINMHFTCRDRNLM
GIQADLLGAHALDVRNILAMTGDPPRAGDYVNATAVFDVDAVGLIRILRRMNEGLDATGS
SIGEPTAFCVGAVLNPAAREPELEVERLRQKLEAGAQWVQTQPIYDLALLDDFLRRAGSP
EIPVLVGVMPLHSARHAEFLHNEVPGITIPPEVRARMREAGDKGLAVGIELAQGILRQAR
RRYAGAYLMPSFGRYEVVAEVLDALR
>A0A7W4GU84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tessaracoccus sp. MC1756|TrEMBL
MASTISRPTTVGELLSAAQGPLFSFEFYPPRSEEEEPILWRAVEALTPLEPDFVSVTYGA
TGSRRDRTIHATRRIATENGPLTVGHLTCVDQSKADIAEALAAYRDVGVTNILAIRGDMP
GGGEWVRHADGLANATELVRFIKDQGDFCVGVAAFANPHETTDDPELDDRILLAKVEAGA
EFAITQLFFDAQSYIDLVRRVRALGCSIPIIPGIMPLTVISQIERFAGLSGRPLPEKFVA
ALRSAASKEEVREIGMATCLELCRTLLDAGAPGLQFFTQNRSKATREILAELKHLS
>A0A2V7AFS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MTNPLRAALGAGRFCYVVELVASALTREARLLETASGLARLPQVVAGSVTSYAGGAMGHD
PLRVAAAARARGLTPNIHLTCVSQDRNDLGKTLADMHALSLENVFALTGDYPSAGDQPPV
FDLDSVQLVHLIDELRRGGMVFHTMVAVSPFKYTEADCVYQYVKLEKKIAAGADAAVTQV
GWDARKFEELKRYLDERGLRTPLLGNVYVLGPKTAERMATGRPAGCWVSPELLAAVRAES
EAKDGGRLARLERAARTVAVLRGLGYAGAYIGGTHDPAQIAWIIRRAGELASSWEPLAAE
LRYGAPGGFYLAAARPRARRGRRDALPRALDRLGRLLPVTRDTPLRRALTRLLAWIDRRP
PAAALLERIELAIKKPMFGCQACGNCVLGHLEYVCPQTCPKQMRNGPCGGTDNGRCEVVP
DKPCIWVAVHDRAKASGSLEGLKTYLPPPHRQLRDTSSWINYFLDRDSRP
>A0A7Z9IXT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MERNSNLTNQLDSPPIESQLVRRLLGGQFALTAEVTPPVSAGSDELLAKAEPLRGIVDAV
NVTDGASARVHLSSVISAAILNANGIEPVVQFTCRDRNRIALISDLLGVGAQSIHNLLIL
TGDDPTVGDQPQAKPVFDLKGHELITIAHKMSQDGIIPSKSVKMTAEGVDPNTRKIETPP
KFFIGAADVPTVKIDEQWLVGLRKKKACGAQFIQTQLSYDMDIIRAYANLLIEEGFTENM
FFLIGNGPLPSVRSAIWMRENLWGVVVPDKIIKRLETAKDSKLEGIRICSEHLQELSQIS
GVAGAHLMAPINVKSIPASIEMASLGNRS
>K4L6T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. CF|TrEMBL
MKISELFKTGKPTLSFEYFPARTEKNAETLEKTLGVLASLDPSFVSVTFGAGGSTREGSY
ELVKKLKQEKKLEVVAYLAAYGLRLDEVAAVLDAYRDLGIENILALRGDLGKDGAKEIPA
DTIHYAYELVTFAKKNYNFCIGVAGYPEGHLEAPSLEKDIEYLRYKVDQGADFVIANFFH
DNIYFYHLLERCQKSGITVPVIPGLMPVYSVKMMEMLAANCGAIIPEQLKKGIASLPEGD
ADALVEFGIQYAAAQCEELLREGACGLHFYTMDRSESTAGIVKILREKGLL
>A0A7Y2ASV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eudoraea sp|TrEMBL
MKVTEHIAKAKGQTLFSFEIIPPVKGRSIQELYDNIDPLMEFNPPFVDVTTSREEYIYID
RAGLLDRKLTRMRPGTVGICASIKHKYEVDTIPHVLCGGFTREETEYLLVDCHYLGIENV
MALRGDAMKEEKYFEPTPGGHLYASDLVTQIHNLNSGQYLHEVIETDNCSDFCIGVAGYP
EKHMEAPSLQTDLKWLKKKVDLGADYILTQMFFDNKKYFDFVKAARKIGITVPIIPGIKP
IAIKKHLQLLPQVFRIDLPQDLIDAVEKCADNKQIRQVGIEWAINQSKELKAAGVPVLHY
YSMGKSDNIKAIAKAVF
>A0A2V7FAP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MPHAFNLRLDAGPLLCDGAMGTMLYARGVSLDACFDVLNLNNPRLVQAIHADYIAVGADL
IETNTFGANRFKLALHGLAGQVREINGRGVRVARDARESTGRDVLVLGSIGPLGKYLAPL
GSVTAEEARAAFREQAEGLLEGGVDAFIVETISDLAEIAHAIEAIRSITDLPVIAQMAFT
DEAVTFTGRSPAEVARTLRALGVQALGANCSVGSSTLYGVLEQMVPAAGGLPLAIQPNAG
LPSRVGERLIYLSSPAYMAEYATRMVDAGARIVGGCCGTTPQHIAAMREALDRKSPIRRE
SVRPTITVSAPAVSESAGLVTRRPATTLQRKLEARELVVTVELDPPRGHTVEKLVQGAKL
LKERGVEIVDINDGSLGRVRMAVLPTALLVREATGLDINMHFTCRDRNLMGIQADLLGAH
ALDVRNILALRGDPPRAGDYVNTTAVFDVNAIGLIEVLKRMNQGLDATGNTIGVPTSFCI
GAALNPGAENIKGEIGRFHRKVHAGAQWVQTQPVYDLAELDRFLEQAGGSPVPVIVGVLP
LHSYRHAEFLHNEVPGITIPDPIRARLRDAGDGALQIGIEMAQRLVCEIRGRYAGVYLVP
SFGRFEVVAEVLDALR
>A0A8A3PEN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monilinia vaccinii-corymbosi|TrEMBL
MHIKDMLSEAERSGNPSFSFEFFPPKTAQGVQNLYDRMDRMQGLGPSFIDITWGAGGRLA
QLTCEMVGVAQSQYGLETCMHLTCTDMGKEKVDEALRNAYKAGCTNILALRGDPPREKEK
WEATEGGFQYAKDLVHYIRQTYGNHFDIGVAGYPEGCDDQDDEDLLLDHLKEKVDAGATF
IVTQMFYDVDNFIDWLGKVKARGVNVPVIPGIMPINTYASFLRRCNHMGCKIPPKWSAAL
EEVKNDDAAVRNIGKDLVAEMCRRIIEAGVHHLHFYTMNLAQATRMVLEELRLTPSTQRP
LKHALPWRQSLGLGRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGQPKSIKDIAELFVSYLESGIESLPWSEAPISSEADIIKSDLIE
LNRRGFLTINSQPAIDGVKSSDPVYGWGPTNGYVYQKAYLELLVAPDMIPELVRRIQHDP
DLTYYAVKKTGDLQTNAQSDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGTDW
AHCHSALSPSRGLIESIMDSWFLVNIVHNDFHKSHGLFPLFDGLTVKNLNEPFEVSESGD
VDGVRFIEPQTVPVTNGQANGH
>A0A7V5AKX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium|TrEMBL
MKAGSNLEKILTAGHFAVTAELGPPKGPDVGVIQKKAEFLRGVVDAVNVTDNQTAIVRMS
SIATCAIVKQLGLEPVMQMVCRDRNRIAMQSDIFGAVALGIKNILCLTGDHHTFGNQVNA
KNVHDLDSIQLINMVRTMREEGTLLGGEDKIEGEVKMFIGGAANPFADPFEFRAIRVAKK
VEAGVDFIQTQCIYDMDRFKEWMKMIRDLGVHEKIHILAGVTPLKSAGMARYMAKNVSGI
IIPEAIIDRMAKAQKGAEEGIKICIEQIQELREIEGVHGIHIMAIEWEHMVRRIVEEAGL
LPRPILS
>A0A2V6WPR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MASSNPLRAALAAGRFCYLVELVASRLAREARLLEIASGLARVPGVVAGSVTSYAGGAPG
HDPLRIGAAARARGLTPSLHVTCVSLDRHGLRKLLEDAAALGIENVFAMSGDWPTAPVGQ
DRPPAVYDIDAVQLVSLIADLRRAGSPFHVAVAVSPFKYLESDCVYQYLKLEKKARAGAD
YAITQVGWDAEKFRELKRWVDERGLRLPLVGNVYLLGPRAAAKMARGEPPGCWVPPELLA
LVERESGGTDGGLGARLERAARTIAVLRGLGYAGAYIGGTQDPELIARLIARGDALAPRW
QEFAAELRFGRPDGFYLYREAPRARRPRREAIPLVLDTLGRLFPVRRETWLRKGLRGIFR
AIDRSRGLARAVERLEFALKQPAFGCQACGNCVLGDLEYVCPMTCPKHERNGPCGGTAHG
RCEVEDKPCIWGAVYARARTAGRLDGLRTYIPPADPGLAGTSSWINYFLERDARPRP
>A0A8C5QJ65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptobrachium leishanense|TrEMBL
NNLLQPCSSSSTENSKENSRCSTPILDLERYEPLRDKMRRRMEAGDKWFSLEFFPPRTAP
GAVNLISRFDRMGSGGPLFIDVTWHPAGEPSSDKETSSMIIASTAVNFCGLETVLHMTCC
RQTKEEITKNLHKAKRLGIKTIMALRGDPIGEEWEEEKDCFNHAVDLVKHIRQEFDDYFD
ICVAGYPKGHPEAESYKQDLKHLKEKVDAGACFIITQLFFRSETYLKFLKDCRDIGITCP
IVPGIFPIQGYCSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSMCRELLD
SGLVHGLHFYTLNQEVATISVLKRIGMWAEDPRRPLPWAVSAHPKRRVEDVRPIFWASRP
KSYIYRTQEWDEFPNGRWGNSSSPAFGDLKDYYLFYLKSKCSRELLLKMWREELSNEESV
YEVFTSYISGEPNRKGHKVTCLPWNDDPLAPETNLLKEELQKVNKRGILTINSQPNVNGK
PSTDPIFGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYQIVNVQGENITNS
TDLLPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEEESPSRMIIQY
IHNNYYLVNLVDNDFPLENCLWQVIEDTFKEHDNPTE
>K4LCX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter sp. CF|TrEMBL
MENAFRKSIQDNNEFIVTWELVPGRGSKEVSQEKALQLAEQAAKGKKIHAVSLTDNPGGS
VGINPEGIGREIKGLGLDAIIHVACKDKNRTQLESQLFSLERSGLHNLLVLTGDHDPGNF
FGRPKPVFDLDSTQLLAFIAKMNDGLELPTAKGVHKLQPTHLFAGAAVSPFKATEAEQML
QYTKLRKKIENGAQFIIPQVGYDVRKYHELYQFVKHNNLHGCLMGNIYLLTYGAAKAMSM
NKVPGCVITDKLVAELEQEKQSSDKGAAAMLDRAAKLFAILKGMGYKGVHLGGHNTTYEQ
VEYIIDRGNELAANWQDYVREFDYPQKNGFYVYAKDEKTGLNTAQKSNDYNNYEKSFDLN
YKMSRVVHKMMFEPNKGMFGFMRGFCHAIKDSALEKPFHGIEHLAKSCMYNCQDCGDCAL
IDVAYVCPMGNCPKNQRNGPCEGSYNGWCEVYPNKQKCIWVKAYYRLKGYSEEEKLNSYH
VSPYNWEKQHTSGWINFFEGQDHSAERLGIKPRTNFEEKE
>A0A7Z9MWL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MERTSNLTNQQNSPPIESQLVRRLLGGQFALTAEVTPPVSAGSDELLAKAEPLRGIVDAV
NVTDGASARVHLSSVISAAILNANGIEPVVQFTCRDRNRIALISDLLGVGAQSIHNLLIL
TGDDPTVGDQPQAKPVFDLKGHELITIAHKMSQDGIIPSKSVKMTAEGVDPNTRKIETPP
KFFIGAADVPTVKIDEQWLVGLRKKKACGAQFIQTQLSYDMDIIRAYANLLIEEGFTENM
FFLIGNGPLPSVRSAIWMRENLWGVVVPDKIIKRLETAKDSKLEGIRICSEHLQELSQIS
GVAGAHLMAPINVKSIPASIEMASLGDRS
>A0A1H9HHP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microlunatus flavus|TrEMBL
MPAPAAAAVRPRLSRPGRGPTVAQLLEAGERPLVSFELFPSKDEEQHRQLWTTIRQLESL
GPDFVSVTYGASGSTRDRTVSATQQIAEQTTLRPVAHLTAASQSREQLRHVVGAYASVGI
NHVMAIRGDMPGGPTVPWEPHPEGLANATELVELVSGLGDFCIGVAAFPDLHPQTRDADL
DARLLVAKQRAGASFAITQLFFTAQRYFDLVARVRALGSDLPIIPGIMPVTRVSQIERFA
DLSGAALPSFVTDRLHEVAHDPSLVRAAGVDLATALSEELLAGGAPGLHFITMNRSSATR
EIYSRLRSHLNRR
>X6GVW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L2C084A000|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGG
PYRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>R6QY02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. CAG:318|TrEMBL
MKLRDILKDEKITVSMEVFPPKTTANYESVEKAALGVAALKPAYMSVTYGAGGSTRGNTV
NIASEIQDRYDVTTIAHLTCVGAGREDIKDTLGRMKEAGIENILALRGDRPKDFEGDPFK
DYHYASELVGDIKKYGDFCVGGACYPEGHPDSATKKEDILNLKKKVDAGCEFLTTQMFFD
NNIFYNFLYKVREAGILVPVVPGIMPITRANQVENAVRLSGCNVPERFKAIVDRFGTNPA
AMSQAGIAYATDQIIDLIANGINHIHVYSMNKPEIAKGILDNLSEIIG
>A0A1M3GTG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriales bacterium 48-107|TrEMBL
MKVIDHIKNAKDTLVSFEVLPPLKGKGIEALYNHLDPLMEFKPAFINVTYHRSEHVFKKN
ADGSFQKVVVRKRPGTESICAAIMNKYDVDTVPHLICGGFDINETEDALINLHYLGIDNV
LVLRGDAAKNETSFEPEPRGHRYASELLQQVVDLNAGIYLEDDLKNTHKTNFCIGVAGYP
EKHFEAPNMDTDMDYLKRKIDMGADYIITQMFFDNEKYYSFVKACRDAGITVPIIPGLKP
IYTRKQLTVLPKTFHIDLPADLANEITRCKSDDEVEKVGEEWLLAQSRDLKKNGVPVLHY
YTLGRPHMVANVVREL
>A0A151AZX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorella mulderi DSM 14980|TrEMBL
MKTESKLEKLLSQGHFVVSGEIGPPKHANPEGIKKHTAQLKDYVDAMNLTDNQTAIVRLS
SIAAGVHVLQAGGEPIIQMTVRDRNRIALQSDLLGAYSLGMRNVLCLSGDHQSFGNHPAA
KNVHDVDSLQLIKIVKDLRDEKKFACGEELKGNEPRFFIGAAANPFADPFEFRVLRLEKK
INAGADFIQTQCIFDMERFERFMAMVRERGLHKKAHIIAGVMPLKSAKAAKYMQQSVAGM
IVPDEIVNRMEKAADPKAEGVAICVEQIKHLKTIEGVAGVHIMAVMWEEIIPTIVKEAGL
YPRPKAE
>A0A3D9MGI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Winogradskyella pacifica|TrEMBL
MKVTDHIKNANGKTLFSFEIIPPKKGNSIQQLYNNIEPLMEFKPPFIDVTTSREEYLYIE
KDGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGINNV
MALRGDAMKHQQYFEACDGGHQFAKGLVSQIQNLNKGHYLHDVLEADDKSDFCIGVAGYP
EKHIESPSLRTDLKRLKEKVDAGADYVVTQMFFDNKKYFDFVKAAKAEGINVPIIPGIKP
IAVKRHLQLLPQVFKIDLPEDLIEAVDRCKTNEQVRQVGVEWAITQSKELQQAGVPVLHY
YSMGKSDNVKAIASELF
>A0A3S0Q3V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidimonas sp. SYP-B2681|TrEMBL
MSPKKAISLEFFPPRDTAAQEKLLRSAKQLLALYPSYVSVTFGAGGSTRTGTADTVRLLK
NLGCDAAPHLSCIGATRAILADILDAYREQGIKRIVALRGDMPSGMGGDQGELHYASDLV
AFIREHSGDWFHIEVAGYPEMHPQASSAAADLDHFVNKVRAGANSAITQYFFNADAYFDF
VERSRAKGIDIPIVPGIMPITNYAQLARFSNMCGAEIPRWIRLRLADFGDDKASIKAFGV
DVISRLSQDLLDNGAPGLHFYTLNNAEVTMAIWRQLRLD
>A0A2M8XDV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 2333.5|TrEMBL
MRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTADLRNIIGQYAGAGIRNMLALRGDPPGDPMGEWVKHP
DGVAYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVDKCRAGADFAITQMFF
YPEDYFRLRDRVTAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQQS
>A0A803KU03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chenopodium quinoa|TrEMBL
MKVIDKIKAAEAENKALFSLEYFAPKTGNGIKILFETMERMVVHNPFFCDITWTTATSNV
TIDIANRMQNSVCVDTMMHITCANMPVEKIDEALDTIKANGLQNVLALRGDPPPGQDKFV
PVEGGFACALDLVSHMRCKYGDYFGIAVSGYPEAHPSVFGPDGVASPEAYASDLAYLKRK
VDAGADLIITQLFFDTNIFLKFVKDCREIGITCPIVPGIYPIVDYKGFVKMTSLCKTKIP
QEITDALESIKDDDEAVKAYGIRLGTEMCKKIFANGIKHLHLYTLNKEESSLKILMNLGL
IESTN
>A0A8J3GTE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudolysinimonas yzui|TrEMBL
MATYTPAQLLEDFSIEMTGKDVPGLLEAAPLIPQGTRINVTFLGNEDLQMRLTASKAVLD
GGFIPVPHISARRLTSQAQLEEFLGALQAQGTSTHVFSVGGDPSTPEGPYEDSHDVIKTG
LLQQYGAQDISIAGYPEGHPDISDEKLWTAITGKHATLTEQGTPGTILTQFGFDEDPVVA
WIEKVRAAGIPYEIRVGVPGPAGIKRLLSFAARFGVASSAGIAKKYGLSLTNLMGTAGPD
KFIKRLAKKLDPAKHGVVKLHFYTFGGLTATSEWIRDFKEKL
>A0A3D1BWF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilaceae bacterium|TrEMBL
RFMDECLIADIDVPVIPGVMPIYNIKQLARFASNCGAEIPRWLRIKLESYGDDLPSLRSY
GVDVISELCEVLIGWDVP
>A0A2E9BL17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp|TrEMBL
MRLPLSFEFFPTKTPEGAVKLRAARQQLYARKPEFCSVTYGAGGSTHQGTFGAVQEILSE
GVDAASHFSCIGATRETVRAQLAELKAMGVKRLVALRGDLPSGYGAGGEFQYASDLVAFI
RAETGRDFHIEVACYPEVHPQARSPEADLQAFAAKVKAGADSAITQYFFSADAYFRFVDE
ARALGIDTPIVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIKAFGLXVV
TDLCARLREGGVPALHFYTMNQSAATLAVXERLD
>A0A542AZE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gramella sp. Hel_I_59|TrEMBL
MKITEHLEKTTGETVFSFEILPPLKGFNINSIYENIDPLMEFNPPFIDVTYHREEYVYSE
RENGLLEKKIVRKRPGTVGICAAIQSKYGVDAVPHILCGGFSKEDTENFLIDLDFLGIKN
VVALRGDAVKSETYFKPEANGHQFASELVEQIRDMNEGKYLDEVIEKGHNTDFCIGVAGY
PEKHMEAPSIDSDVRRLKQKVDAGAEYVVTQMFFNNQCYFEFVEKCRDQGINVPIIPGLK
PLATIKQLSLLPHRFHVDLPEALIHEVEKCENNQEVRQVGVEWCIQQSKELIKGGAPVLH
YYSMGKSTNIRQIAEAVF
>A0A4D4JN53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. NB1|TrEMBL
MNAANAQGTGFPVSFEFFPPKTPEGADKLRVARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVGAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLKAYVAKVQAGADSAITQYFYNSD
AYFRFIEDTQRLGANVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>M5JNN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella intermedia M86|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDVKPAAHLTCVDATREEVDRVVREFASLGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKAEAAL
EMA
>A0A1U8QH56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)|TrEMBL
MEKITHKIAALPPGANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKKYGDYFCVGVAAYPEGHPADSFQDIQDPKVDLPWL
VEKTQAGADFIMTQLTYDIDAYTEFENLLRNHESGTFKTIPIIPGLMPIHSYKILTRVTK
LSHVKIPPPILAKLDEVKHDDDAVKRLGVDILAELVDGMKKLPTPGLRGFHFYTLNLEKT
VSFILERCKLIPDHDDDAEAVADGVSLLTVDAEIANRRRRASSISSLPHNRVIVDKVSNG
SSKDSVTHEATAASAGLPAGPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFG
EIDGYGPSLHVAPSVAHRIWGYPVSTDDISKLFRRHVSGDLHMVPWSEGGAEENTSGLNA
ETETIRPELLALIDKKGWWTLASQPAVNGVRSDDPIFGWGPPGEGFVFQKPFVEFFCPAS
DFKTTLKPLLQKHGHEKLAWFATNAAGDFESSLPAETSDTEPVEMNPNNVNAVTWGVFRG
KEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKSSATEKFLEKTKNDVWLVCVVGQDFG
AGTEVGSKEEDDEKKWMWRLLADC
>A0A2T6ZXB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tuber borchii|TrEMBL
MDKVVNKIAALPPGEPYHSLEFFPPKTAMGFQNLQARLERMARALRPLFVNVTWGAGGST
ATKSLELAEICQRQLGLTTALHLTCTNMSQAVLDETLEAAKEIGIRNILALRGDPPRSDD
YHNTPCDGASNGARKEFEYAVDLVRHIRERHGDYFCIGVAAYPEGHVEGASPEKQDPLFD
LPFLVEKVKAGADFIMTQLFYDVDKYLWFEKLLREEPSGVLSELPVVPGLMPIQNYSMLK
RITKLSGASLPAGILQRLDDVKGDDEAVKQVGIDIVSEVIEKIKAANLSGPRGFHFYTLN
LEKSVSFIVERTGLIPPRDESVFEEIEGPAVNGVALRRDRRTSSVTSDPHNRVIVDNSSS
LQSPRLANALEAGFLGPPEQSRPPEVALAISEGEGALGREATWDDYPNGRFGDARSPAFG
EIDGYGPSLHLSQAQAIKLWSCPVNKQDVSDIFVRHIKGELNAIPWSEQGLSVESKVIAD
HLTKLNQKGFWTVASQPAVNGANSTDETFGWGPRGGFVFQKAFVEFFCSTEDWEILRAKL
EGVEDVSYYAANKNVSRSSPRTK
>A0A0A8ET50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 769|TrEMBL
MRDLLASGKRSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTAELRNIIGQYADAGIRNMLALRGDPPGDPMGEWVKHP
EGISYAADLVRLIKESGDFCVGVAAFPEMHPRSTEWDADIRHFVDKCRAGADFAITQMFF
YPEDYFRLRDRVRAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQRP
>R7H2Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella stercorea CAG:629|TrEMBL
MNISDILTSGGGEKHFSFEVLPPLKGTGTERLFSTIEKFRDFDPAYINITTHHSEFVYRE
LDNGQYERLRVRRRPGTVAIAAAIQNKFGVPVIPHVICSGATADAIEYELIDLQFLGIEN
VLLLRGDKARDDSQFVPTPGGHAHTTDLIEQVNRFNDGFFNDGTPIKNPGKKFHYGVACY
PEKHEEALNMDIDLKYLKMKQDMGADYAVTQLFYDNRKYFRFVEKARQMGITIPIVPGIK
PLAKLSQLTVVPRVFRCDFPQELAVEALKCKTDDDARQLGIEWSTEQCRQLYKAGVNNIH
FYTVSAVDSVREVARRLL
>A0A4R1FT12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Volucribacter psittacicida|TrEMBL
MSYAKEIDALNQCIADLSGNINVSFEFFPPKNEKMEQIFWHSVDRLKVLNPKFISVTYGA
NSGERDRTHSIVKSVKEQTGLEAAPHLTGIDATPEELVEIAKDYWNSGIRRIVALRGDEP
KGYTKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCVATGIEVEIVPGILPVTNFKQLQKMAAVTNVRIPHWLARMYEGL
DNDQATRNLLAASVAMDMVRVLSREGVKDFHFYTLNRCELTYAICHTLGVRPEIV
>A0A519F3C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp|TrEMBL
MGLPLSFEFFPTKTPEGAVKLRAVRQQLYAHKPEFCSVTYGAGGSTHDGTFGAVREILQE
GCDAASHYSCIGATKATVRAQLAELKAMGVKRLVALRGDLPSGYGIGGEFQYASDLVAFI
RAETGRDFRIEVACYPEVHPQARSPQADLQAFAAKVRAGADSAITQYFFSAEAYFRFMDD
IGRLGLDVPVVPGVMPIISSTQLMRFSDACGAEIPRWIRLRLQAYGDDIASIKAFGLDVV
TDLCERLRRGGAPALHFYTMNQSQATLGVLERLG
>A0A177TS50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tilletia indica|TrEMBL
MPATTTTTPPTAVTPRGDESWKITAKLAKAERENRIWWSFEFFPPRTAQGLNNLYDRIER
MSDLGPEFVDITWNAGGRTSDLTSSLVKTVHTYFGLETCMHLTCTNMPREKVDDALKDAK
EHGCRNILALRGDPPAGQSQWEAHAAGFTCARELVEHIRANYGDYFAIAVAGFPEGHPET
TEGREKELEYLKAKIDAGADFIFTQMFYDFDIFASWVKEVRAAGITVPIIPGVMPIQNYG
GFERAVARFRTLVPQYFHDALDPVKNDDQAVRDVGTQLVGDMCRKILESDLGIRGLHIYT
MNLERGSRMLLDYLGLTPSVNQVKQLPWVPSLTPKRREEKIRPIFWANRAKSYLSRTETW
DEFPNGRWGDARSPAYGDVNAYGVSLNLTDTEARELWGAPESLDDVKALFQKFCSGDLKA
LPWSDTPVAKETSVIGGQLEKLNGRGFLTINSQPAVDGAPSDDKVHGWGPSNGYVYQKAY
LECFVAPEKLDEIIAHFDRDPQITYHAVNAQGDMRTNTQSDAPNAVTWGCFPHSEILQPT
IVESISFLAWKDEAYELGRKWAAVYEPSSPSRKLLQGLFDSWFLINVVHNDFKQPDAIFK
VFESLGVAKNGTNGHA
>A0A7K4RY93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Columbina picui|TrEMBL
MVNEAQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRLDSGDR
WFSLEFFPPRTANAAVNLISRFDRMAAGGPLFVDVTWHPAGDPASDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITANLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVDL
VKHIRSEFDDYFDVCVAGYPKGHPEAESYEADLRHLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A8H5Z8B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cochliobolus sativus|TrEMBL
MHISQKLAQAKREGKPTFSFEFFPPKTAQGVQNLYDRMDRMHSFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALREAYQAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDDVDELIDHLKEKVDAGGSF
IVTQMFYDTDLFLEWVRKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTKCHIPDDWTKAL
EPVKNDDVEVREVGKTLVADMCRRLIDAGITHLHFYTMNLAQATRMVLEELELLPDVESP
LEKPLPWRPSLALNRREENVRPIFWRNRQRSYIARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPLTIRDLSNLFVRYMEGKVESLPWSEQPITAEASSIRDDLID
LNRRGFLTINSQPAVNGVKSSDPVFGWGPRNGYVYQKSYLEVFVSPEHIAEIITRLERDP
EFTYYAVNKNGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDVIDTWYLLNIVHNDFHATRGIFPIFNGLEVKDMDKPLHTPSADL
PNANGSETVNGAKGVNGTNGTHKEESPSLIDVAKAAAIEVTNGMKSLAVSN
>A0A8H5ZUE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cochliobolus sativus|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTACLHLTCTNMNRQLIDEALEQAQVLGIRNILALRGDAPRSEE
YRDEDTPPEQDSNKDFTWAVDLVTYIRKQYGDYFCIGVAAYPEGHSDQSHPEHQDPMADL
PYLVEKTKAGADFIMTQLFYDVEAYDKYEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHAKLPTDILARLDAVKSDDELVKQVGVQIMDEIVERIKARPDTCRRGFHFYTLNL
EKAVSHILEDTKLIPSTLIDDNEVIVETTPAINLEPPPNGIMPHRRRSSAVNSGPRNRVI
VSHVSAARSSNPSYEATEEEAGIPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPTEKNDISTLFRRHIEGDLEAIPWSEQGLSP
ETLTISKQLLALNAKGWWTVASQPAVNGIKSTDPVFGWGPKNGYVFQKPFVEFFIPASEF
AALQPKLDAHDQITYFAGNAAGDFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIWREWQRIYPPRSATSTLLGELRRDYWLVNVIWGDFVNGEGLWEFLLE
>A0A7N6B7P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabas testudineus|TrEMBL
MVNQVQRGGGSWQSCKSDSSGASNSGGESSKESSRCSTPVLDADRLDRLRDKMRRRMESG
DRWFSLEFFPPRTAGGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCCNQTKEKISGHLAKAKHLGLKNIMALRGDPIGSDWEEEEGGFNYAV
DLVKHIRSEFDDYFDICVAGYPTGHPEAQSYDEDLQHLKEKVDAGADFVITQLFFRADTF
LKFLDDCRANGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGRVPGLHFYTLNREVATMEVLRQLGLWIEDPRSDIVYHLLHTEA
KVRSTVAGSYSKMTEQFVVTGAFRGNSSSPAFGELNDYYLFYLKSKSSKDALLQMWGEEL
MNEESVYEVFTCYITGQPNRSGHKVMCLPWNDEPLAPETNLLNDELEKVNRRGVLTINSQ
PNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSSENVDALLQVLKKYEPRVNYHMVNVHG
RNMTNATDLQPNAVTWGIFPGREILQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPS
RMIIKYIHDNYFLVNLVDNDFPLESCLWQVISDMFELLDAPPEPLTDRAV
>Q1YM37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantimonas manganoxydans (strain ATCC BAA-1229 / DSM 21871 / SI85-9A1)|TrEMBL
MSQTPPLAGSGLRVSFEFFPPKTEKMEENLWRSIERLAPLGPSFVSVTYGAGGSTRERTH
QTIERILKETTLTPAAHLTCVDASREEVDEVVRQYWETGVRHFVALRGDGQNGVGGKYVP
REDGYRNAVELVAGLKAFADFEISVAAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNDVFERYVERVRRAGIYIPIVPGIVPIHDFVKVARFSNATGAKIPSWLAERFDGLEE
DPQTRSHVAAAVCAEQVLDLQKRGLSDFHFYTMNRADLVYSICHILGMRAGTAAAPKSEA
AAA
>A0A8J3FK07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mangrovihabitans endophyticus|TrEMBL
MSHGLTPRRPGSPAIGDLIRRPGPTFSFEFMPPRNREGEQLLWQTIRELEPLRPDFVSIT
YGAGGSTRDTTVSVTERVATETTLLPMAHLTAVNHSIAELRNVIGRLAGAGIRNVLAVRG
DPPGDPTGEWVQHPDGVLYAEELVRLLRESGDFSVGVAAFPYKHPRSDDIESDTRNFVRK
CRAGADFAITQMFFDADEYLRLRDRVAAAGCDTPIVPGVMPVLRMGTIARAVQLSGAPFP
PALLERFERIAGDDAAVRALGIDLCGEMCRRLLDEGVPGIHFITMNRSTATREVWQRLAA
SVSA
>A0A1M5XZD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrimonas marina|TrEMBL
MGFHHAQQVEALNERLSSLTDLNVSFEFFPPSTPQMEETLWESIQRLSPLKPKFVSVTYG
ANSGVRDRTHKVIERIHAETELQAAPHLTLVDASDDELRQLARQYWQQGVRHIVALRGDV
PAGQPNPNRYASDLVTLLKEEHDFEISVAAYPEVHPEASSAQADLINLKRKIDAGADRAI
TQFFFDIEAYLRFRDRCAAAGIEAEIVPGILPVTNYQQLLKFADFAKIRVPNWLHHMFDG
LDDDPATRKLVGANVAIEMAKVLAKEGVSDFHFYTLNRAELSYAICHALGVRPGV
>A0A4R7MBF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 846.5|TrEMBL
MPSVDTASAIAVLLEDFSLEMTGKDVPKLEEARGLIPAGTRINVTFLGNEDLPMRLAAAQ
AVRRYGFVPVPHISARRLRSQAELEVFLAALHSGGTSDSVFVVGGDPAQAHGPYAEALSV
IRSGLLQQYGVRDIGITGYPEGHPDIPAPALWSAIEGKAAALAEQEVPGSVITQFGFDVD
PVLAWVEQLRARGVTLPVRIGVPGPAGIKRLMSYAARFGVGTSASVAKKYGFSITNLMGT
TGPGKFIHALGERYDAERHGELRLHFYTFGGLRATSEWIADFKREALA
>M6VRW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira noguchii|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELFLLDPDFVTVTYGAGGSTRDK
TVQILSQISKNYSIPTVSHFTCVGANKDQILETLKGIRSSGIVNLMALRGDPPKGEGEFK
KVENGFGNATELISFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVKNLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCKELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A5F0ERV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT2-14|TrEMBL
MPHTSDPACRKIPFSFELYPPTSDAATSVLHATIERLAAAGPEFISVTYGANGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSNAESSQLIREFLDAGVRSFLALRGDPPEGIREGEAF
LGDLGSAAELVQLIHRVQAERVPYREAVIPGLPAARTIKREREKVRIAVAAFPNGHPRSR
SATQDIDALLAKQAAGANLAITQLFFHADHYLSFILRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRQATELARQLIAGGAPGLHLYAFNQHE
TVLAVLDGCGLLTPTLPASALPAPHPVKENS
>A0A2I0GSM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. 4Dc|TrEMBL
MSKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALST
RGTTEIAPHMSCIGDDKSEIAELLEYYKTLGIRRLVALRGDLPSGQVGMGELPFAVDLVK
YIREHSGDHFHIEVASYPEMHPQARSFEFDIDNLVNKYQAGANASITQFFYNADSYLYLR
DKLEKRGIDTVAQPLVAGIMPITNSSNLLRFADSCGADIPRYVRKQLTDFGDDRKAIREF
GFDVVYRLCERLIAEGVPAMHFYSMNKVEPNKRLVEALGLTA
>A0A2N9NDP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfotelmatobacter sp. SbA7|TrEMBL
MSTGGCCEVPNRFRSALEQGEFVCTAELVLGRDHSAVEAEVFVKEASQQEHGIDAISLTD
LPGGNPALPPEAFVACVLEHKLTPIAHLTGKDGNRLSLESRIHALARLGVENILALTGDA
QKEGFAGQPKPVYDLDSVLILWLLRALRGGLEYNLGPKTARTTPFDFFAGAVVNPFKVRE
PDLMMQFYKLQLKVAAGAQYIITQLGYNLRKLYELKQYMAREGLGHIPVLANVYVPTAKI
ARLMQTGELAGCVVADELIQRLEREKKPQRLERAALMVAAVKDLGFAGAHIGGFGLTHKD
FMTILEGAAAIGKNWRGRIDELVFPIPNEFYLLPQGGDGLSDGAGDYRISGVKPHASWAQ
RLSASVHGHLIREGSFGARLFAAKLKTRIMKTGGLPGKNSSWRHGLWYGLLEPATLYRKA
TLGCVSCGDCIQDHLNYAGCSMQGCYKELRNGPCGGSRVDGNCEARADLPCIWNLIYLGT
LAMGDDPKKFAHVLIPPRDWCLDRTNALANRFAGLDNLCKRIDLGSPVEEGHPKETKPC
>A0A7W6BWG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureimonas phyllosphaerae|TrEMBL
MIQRRDTRPPIRVSFEFFPPKTPAMEQSLWSAIERLAPLHPDFVSVTYGAGGSTRERTHH
TVERILKETDLAPAAHLTCVDASRAEVDEVVRQYRATGVKHFVALRGDGQGGAGSAYVPH
SEGYRNGAELAAGIKAIDPEIEVSVSAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNDLYERYVERARRAGIYVPIVPGIVPIHDFSKIARFSAATGTSIPLWLAERFEGLEN
DAQTRSHVAAAVCAEQVLDLVDRGVSDFHFYTMNRADLVYSICHILGLRETARVDEAAAA
>A0A7S1QKD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neobodo designis|TrEMBL
HANGIRCPILPGIMPVQSRAQFRHWFDKPGCEDLKRRVDAANRHDDAEVKRIGVEFTTAL
LKQLFRGGVRGAYIFTMNMETVVTSIIGACGLGKRAPKEMPWRQSADQSRSERERQRPIY
WSGRPTSYMARTLGPTDDFPNGRYGDSMSPAFGENTT
>A0A2K9JNT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aestuarium zhoushanense|TrEMBL
MSRPNVSFEFFPPKSLDQSFRLWNCATTLAPMNPTFVSVTYGAGGTTRQLTHEAVGAIHK
NIGLTVAAHLTCVEATRAETLEIANAYAEVGVTEIVALRGDAPKGAEKFRPTADGFQSSI
ELIEALADTGKFKIRVGAYPEKHPESGDAAADIEWLKRKIDAGATSAITQFFFEAETFFR
FRDACEKAGIDAPIIPGILPIENWNGARKFAQMCGTSIPQIVADAFDNAAKTGSTDLLAT
ALATELCDDLIRGGVNDLHFYTLNKPDLTRDVCHALGVTPQVKLENVA
>A0A1K0JEQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus necator|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLENFVRKVKAGANSAITQYFYNADAYFRFVD
DVRATGLEVPIVPGIMPITNYTQLMRFSETCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLTAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A1D8TV13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena producens PAL-8-15-08-1|TrEMBL
MTNPTKNSFRTAVESGEFLITAEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQQGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFEK
KLEAGAEFFQSQLICDFDRLEKFMDQIAAGTNKPILAGIFLLKSAKNAKFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSPVNDFVCK
>A0A1B1YNE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoclostridium stercorarium subsp. leptospartum DSM 9219|TrEMBL
MKITEFFERKKQTVSFEIFPPKLDTPIETILNKLGDFAQLKPDFISVTYGAGGSKKGRTV
EIASKIKNEYGIESLAHFTCVGHSIEEIDDMINKLKNEKIDNILALRGDPPKDMPDFDFS
KNVFSYASELIRHIRKRANFCIGAACYPEGHVDSPRIRQDIYYLKQKVNEGVDFLITQLF
FDNRIFYDFMDKLLAAGITCPVLPGIMPIFRADQIKRIASMCGASMPAKLVLLLDKYGNT
PDMQKAGIEYATNQLKDLLDNGVHGIHINTMNNVEATRTILQNLGLFPG
>A0A1Q5KFI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TSRI0107|TrEMBL
MALGTASTRSDHAPTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVPHPQGLTYAADLVELIKTSGDFCVGVAAFPAMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFHPEDYLRLRDRVAAAGCETPIIPEVMPIGSVRTLERIPSLTNAAF
PDALKERILTAKDNPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A2H0AUL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG23_combo_of_CG06-09_8_20_14_all_45_10|TrEMBL
METKSNLERVLEAGYFTVTAQINPPRNTEPEAIREKANLIKGYVDAFNIPNGESAVVAIA
SGAACLIRKQEGLDPIVQMTCRDRDRIALQMDILGISAFGVNNILCLTGDPVSFGNCPEA
KSVFDLDSIKLIRMVKGLRDEKRFENGELIAGREPRLFIGAVADPFAVPPEHEVIRLREK
VAAGADFIQTQSIYNIKKFRRWMEMVRERELHKKVKILAGLLGGKRAQLKGEVEGPLPLL
SQAQSLPTRWP
>A0A1E9HPB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. HMSC063G07|TrEMBL
MEHAHQSRQSASAPALAEDFAAELRFPRPVRPALSFEVMPARTPQAREVLPELISALEAY
GPDYVAITSSAKSGWVQGTADFVRELSATTRLRPLAHLACTAAPTVELLEWVEQFIDAGV
RGFLAVRGDLAAGQTRPPENHLPHADALVTRVRQLEKRSAARFCGGRLSLGVAAYPSGHP
ESSGPDEDLDVLAAKQRAGADFAITQLFFDTSAYSRLLRSAHLAGVTMPIIPGILPITSS
ARLNRMAHLSGLVPPQRLTEQLEGARSPAHARDIGLAATVELAQRVLDAGAPGLHFYTFN
DPRTTLEVLNRLGIAARTVGAVGREAV
>R8YQD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii ANC 4050|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGFPAAMTLADRVHSDHDIAPLEASKS
YPESIEKVLHFSGKARDIQDFEHFLEQAQSANIQNLLLLTGDKLKEHHHGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHNYSQQILACVMPLTLARANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLELKALEELWNSLWQVT
TGKEFVPEITHFSRQPTSKQIIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHTLVGCESCGQCRLSDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAIEQTEILKEKLIPTVPIETRGTSSWKNWYLATEA
>I3CCL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beggiatoa alba B18LD|TrEMBL
MTATKPLWISCEFFPPRTDEAATKLKQVQARLKVLNPTYYSVTFGAGGSTQEKTYETVVD
IQSNVGIPAAPHLSCIGSTRDNIRQLLKAYQEKNISRIVALRGDQPSGWAGRLGDFNYAN
ELVEFIRAETGQYFHIEVAAYPEIHPQAKTAESDLQYFVQKVNAGADSAITQYFYNADAY
FYFVEAAQKLGVTIPIIPGIMPISNYEQLTRFSDVCGADIPRWLRKRLESFSDDKASLQA
FGIDVVTNLCQRLIDNGVTGLHFYSLNQSELTLRVARNLGLIPA
>A0A8J7A215|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fortiea sp. LEGE XX443|TrEMBL
MDHTHSTTALSLFQKAAQAGEFLVTAEVAPPKGGNPTHMIEMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQNGIEPICQIACRDRNRIALQADLMGAHALGIRNILALTGDPVKA
GDHPDAKAVFDLESVRLLQLIQKMNQGFDCNDKPLTDGATDLFAGAAVDPQCASWSGLQS
RFERKIAAGAQFFQSQLITDFERLEKFMDKIASVHKKPILAGIFLLKSAKNAQFINRCVP
GVNIPEHIIDRLGKAKDPLEEGVKIAAEQVQIARQLCHGVHMMAVKREDLIPQILDLAGV
KPVDLVVAK
>A0A256XLM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon ex4572_165|TrEMBL
MNFKSNLHRVLKQNHFAVTCEIGPPKSADSSIISKKADLLANCMDACNITDNQTAVVRLS
SLAGSVLLKQKNIEPIYQMSCRDRNRIALQSDILGAVALGINNILFVTGDHQSVGNHPHA
KGVFDIDSIQLVSIAKSMRDKGIFQNGEPLKKPFFNLFIGAVCNPFATPYDYRVDRLEKK
INAGADFIQTQSVFNIDHFQNFMDKVISRGLDKKVFILAGVTPMKSEKMMDRMKFHVPGV
DIPDDVYNRLKNADDFQAESQIVSCETINSLKKMKGVHGIHITALFWESIIPSFLERCNF
LPRP
>A0A634N674|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella senftenberg|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A659V6S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M00.F.Ca.ET.158.01.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARYEVDAVIQEFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A5R9L6A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter luticola|TrEMBL
MFLEKIKSGESGVILYGITPPKAGTTPERVAEIAEKTLERLSSLDIDALVVYDVQDESAR
TSEERPFPFINALDPLTFASEHLGGLNIPKIIYRPAGKFSAEELESWLEDLHNQQFYPVF
VGVPAPDFPVKTSLPQAYKIWEKHQETSVIGAVTIPERHKVLKDEDVRILDKMTCGVSYF
ISQCVFDLEYAKQVIEDLSNTCKNKEIAPPTIIFTITACGSAKTLDFMGWLGIHIPDHIQ
EELKAAEDMLEKSVGICLNIASELTAYCVERGIPFGFNIESVAIRKSEIEASIEMARSIG
QMLQDKGVRKSSGGLVTSH
>A0A1L7I5F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gramella flava JLT2011|TrEMBL
MKVTDHIEKANGKTLFSFEIIPPKKGKNIQELYDNIDPLMEFQPPFIDVTTSREEFVYVE
RDGLYDRQITRMRPGTVGICAAIKHKYNVDTVPHVLCGGFTKQETEYLLVDCQYLGIENV
MALRGDAMSHQRYFEPADGGHNFATDLVKQIKNINKGRYLHDVVETDHLSDFCVGVAGYP
EKHMEAPSLKSDLKRLKEKVDAGSDYIVTQMFFDNSKFFEFVKEARAMGINVPIIPGIKP
VAVKKHLQLLPQVFKIDLPEELINEVEKCKSNKEVREVGIEWCIKQSKELMDFGVPVLHY
YSMGKSSNIEKIASAIF
>A0A177N649|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas lenta|TrEMBL
MNISFEIVPRSLEAFDQQYAFVQKLDDGIHFINVPDIQRFDTRSWELATRIDRRKYRFIP
HFRAIDFKIDSGELFRIIEDYQLDSVLLVTGDPPEGLKRAFYNTDVVDLIRVVRLRFPAL
NIYAGFDPHRQGLQDECDYIQRKADAGARGYFSQPFYDKRLIDIYAEHMQGLETFIGISP
ITTQASMNYWEVKNKVKFPLNFRPDYDWNVSFANDVMASAAANGLNVYFMPIRIDLERYF
GGIRLGVA
>A0A1V6DTW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium ADurb.Bin118|TrEMBL
MQSNVLVRDLYAARRAAGRPVVSFEFFPPKTADGERGFFDRTLPQLAALKPDYCSVTYGA
GGSTRDKTLALVEAIQQRHQLPAMAHLTCVGSTEAQIREIIAQARARGIHNILALRGDPP
AGESQFQQTAGGFEYAWQLVQLLREAGDFSIAVAGFPEGHPACHAGRHVDWERLREKIAY
GADLVITQLFFDNRLYFEFRDFLAKQGVTIPLVPGILPILNVTQIKKITLLCGATIPPAL
LARLEELAGDDAASTEFGIEYSTRQCEELLRAGAPGIHFYTLNKVRSTTRILQNLGLV
>A0A3M4U1R1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas syringae pv. coriandricola|TrEMBL
MSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKEDLRSLLAQYKDAGIRRIVALRGDLPSGMGMASGELRHANDL
VAFIREETGSHFHIEVAAYPEMHPQARNFEDDLKHFVTKANAGADSAITQYFFNADSYFN
FVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVQSIQAFG
EDVITQMCERLLEGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A134CBT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella sp. DNF00869|TrEMBL
MSETIQQKRPTLSYEIFPPNTQVGDEKIITVLDELKSLKPEFISVTCSNKQRNIEETTIK
LSNYVQNTLHIPTKAHLPAIYLSKEQVRSVIDQLDQLGIHKLLALRGDILEDLPPVGDFK
YASELVHFVKDYAPHFQISGACYPEVHPDSPNQLQDIKFLKEKVDAGCELLVTQFFLDNN
VFYDFQEKCALAGIDVPILAGVMPIINRNQALRLLTSNATAIPRKFKAILDKYEHDPIAL
RDAGLAYALNQIVDLVTEGVSGIHLYTMNQSNTALYIENAARSLFSSPIYENQ
>A0A2A2QRA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium Tous-C5TDCM|TrEMBL
MSSPSVSTSSDCPISDFFALGRPLRSLEFFPPKDDAGVEALRATATALRSISPDFVSVTY
GAGGTTRERTAQVSALLRQELGFTVMPHLTCVGHTRAELHDLADRIHAGGFRNIMTLRGD
PPKGATTFTATADGLRYANELVALLKARHPDFCLGVGGYPEKHPEATTLAADLDALKRKV
DAGAAFVTTQLFFDNAVYYRFVEKCRAAGINVPIVPGLMPVLSLKQVQRFTAMCGAALPP
ALIKRLEVAAENTEVVEIIGLDWALTQIRDLLAHDAPGYHLYIMNRAKSALALAAGLAA
>A0A1J4N321|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides luteus|TrEMBL
MVTGRGRSLAELINQGERSFSFEFFPPKDEAGEEQLWNAVRALEPYRPTFVSVTYGAGGS
TRDKTVAITGRIAAETELLPVAHLTCVGHTRDEVAAILDSYAAQGVAHVMALRGDPAEGP
RAAWTPTPGGLDHAIDVVRLAKERGDFRIGVAAFPEGHPSAESIEADADVLVAKARAGAE
FAVTQMFFRAADYFGLVDRVRARGVDIPILPGIMPILNLAAIRRQSELIGAEVPEEIVER
LTAAGPEPADIRAEGIAVAAELCQELLDGGAPGLHFYTLNRSKATLEIFAKLNVTV
>A0A416VSV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. AF16-49|TrEMBL
MKVIDLIRSNEKTAFSFEILPPLKGTGIEKLYNTIDTLREFDPKYINITTHRSEYVYKDL
ENGLFEKRKMRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHEAAFTPEGNGYHHAIELQQQINDFNKGLFVDGSPIKVTGTPFSYGVACYP
EKHEEAPNIESDIHWLKKKVEAGAEYAVTQLFYDNRKYFDFVKRVREEGINVPIIPGIKP
FAKISQLSMVPKTFKVDLPEPLAQEAAKCKTDEEAKQVGIEWCIQQCKELMAHGVPSIHF
YTVSAIESIKQIAKEIY
>A0A7W2LN27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas juntendi|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAACNPNFFSCTYGAGGSTRDRTLNTVLQLE
SEVQVPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRTETGDHFHLEVAAYPEMHPQARNFEADLGNFVQKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEASLALWNNLKLPR
>A0A8H4F6U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces cerevisiae|TrEMBL
MSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKT
LTLASLAQQTLNIPVCMHLTCTNTEKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVE
AGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
AILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETVANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWET
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKA
WRDEAFSIWSEWAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETDELWEMLLDQA
>A0A2H9UHR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 5347|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHKVAGIVITPHMLRVLAQEKQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVET
KKELVPELAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPEACPKGLANGPCGGTTLDRCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A7W7SV93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora polyrhachis|TrEMBL
MALGLPSVLPQSQPSIGELIQGSRPTFSFEFLPPKTAEGERQLWQAIRELEPLRPSFVSI
TYGAGGTTRDTTVSATERVATETTLLPMAHLTAVNHSVAELRHVIGRLAGAGVRNVLAVR
GDPPGNPTGEWIQHPEGMLYAEELVRLVRESGDFSVGVAAFPYKHPRSPDITTDTAHFVR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPIVPGVMPVTQIGTIERSVQLSGAPF
PPALATRFERIADDPEAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATRKVWHNLQ
LAARV
>A0A0S6TEW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter frateurii NBRC 103465|TrEMBL
MMLAQTGPLPAISFEFFPAKTEKAAVTLLENAKTLAAFGPQFMSVTYGAGGSTRDRTLAT
LKDMVRETGAPMAGHLTCVGASREGVEAVARAYWDAGVKHIVALRGDPPPSAGGVYEPHP
EGYAGAVDLVRGLKEIAPFEISVAAYPETHPAAFSPQADLEHLRAKIDAGADRALTQFFF
EADTFLRFRDRAVAVGIEQPIVPGILPVGSAAQAWKFAEMCGANVPRWIRDLFDGLDETP
QTRALVAATIADRLCQTLRAEGVEQFHFYTLNHADTASALCRLLGRRPL
>A0A1V1WU17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium S7086C20|TrEMBL
MSLKAALESGKFVVTAEVAPGKGTDVEHLLEDAAVIKERVDAVNVTDLQSSVMRLGSMAF
SHFLTDVGIDPVYQVTCRDRNCLALQSDLLSAWALGIKNVLALTGDHPTMGDHPKARPVF
ELDSVSLLDVIGKLNSGVDMAGNELKGKPDFLPGAVVNPGADNEAALDLQIMKMETKIKA
GAKFFQTQGVYDLDAFEKFMKRVEGFDAKILGGIILLKSVGMARFMNKNVAGVFVPEPLI
QEIKAAENKAEASINIAVRLVEGMKDLCHGVHIMALGWESKIPQILDTAGL
>A0A436H2Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.16.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>E6LCE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus italicus (strain DSM 15952 / CCUG 50447 / LMG 22039 / TP 1.5)|TrEMBL
MDRLISFEVFPSNTQDDFTKLVATIQELAKLNPAFISVTCSNNNQTIDQITIKVANYIKN
ELGIETIAHLPAAYLSKAQVKRTIENLTRLGIYHVLALRGDTLPNLKPVHDFLYASDLII
YIKTIAPEFSISGACYPEVHPDSPNRISDIQALKLKCDVGCDSLISQLFFDNDLFYEFIE
RCQLAGIDVPILAGIMPIVNRKQAIRLVQTTKTNLPRKFLAILEKYEHNPKALGEAGLAY
AVDQIVDLLTQGVGGVHLYTMNNANVAEHIYQQTGALFATASCFGQEK
>A0A3M7TEJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium nematophagum|TrEMBL
MKITDHIKKANGKTLFSLEVVPPQKGIGIEDLYANIDPLMEFKPPFIDVTTSREEYVYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKDETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMDLVHQINDLGRGKYLHNQDQICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVQKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELIAEVEKAKNNDMVKQIGVEWAITQCRELLDFGVPVL
HFYSMGKSDNIKNVARELF
>A0A2K1E1D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hanstruepera neustonica|TrEMBL
MKVTEHIKNANGKTQFSFEILPPLKGQHIQSIFDNIDPLMEFKPPFIDVTYHREEYVYKE
LENGLLKKQVVKKRPGTVGICAAIQNKYGVDAIPHILCGGFTKEDTENFLIDLDFLGIYN
VMALRGDAVKTETYFRPEKEGHAYASELVNQIQELNQGNYLDDDLQNSSKTNFCIGVAAY
PEKHAEAPSLESDIHFLKKKIKKGAEYIVTQMFFDNEKYFKFVEKCRNEGIGVPIIPGLK
PIATKKQLNLIPHRFHVDLPEALILEIIKCQDNTQVAQVGMEWCIQQSKELQKAGIPVLH
YYSMGKSDNIRSIAQAVF
>A0A353U3G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinilabiliaceae bacterium|TrEMBL
MKTAAQLIRELEKPGFSFELLPPLKGNSINGVYNTIEQLKEFNPLFINITSHRDEVIYRD
IDKGLFERRITRKRPGTVAVAASIQHRYGIKVIPHIICSGFTRSETEYALIDLNFLGIHD
LLLLRGDRPDRKSPLVELQGERNEHAIDLIKQVNSINKGVFLDDTQADAFETPFSYGVAG
YPEKHEEAPNIDSDIYWLKKKVEAGAEYIVSQMFFDNSKYFEFVKRCRDAGITVPIVPGL
KPLTFLNQLTVLPKIFHVDIPEAFAKELRRCKSDEEAASAGVEWTIMQAKELLSGGVNLL
HFYTLMATRSVKEVAAAIY
>A0A1J5L425|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium MedPE-SWsnd-G2|TrEMBL
MTVIEHIEKAKGETQFSFEILPPLKGEHINSIFENIDPLMEFKPPFIDVTYHREEYIYKE
LANGLLKKQIVRKRPGTVGICAAIQNKYQVDAIPHILCGGFSKEDTENFLIDLDFLGIKN
VMALRGDPIKSEIYFKPETDGHAYASDLVNQIKALNKGQYLDEELQNSSKTKFCVGVGAY
PEKHMEAPSLVNDIKFLKEKVENGADYIVTQMFFDNQKYFDFVDKCRSEGITVPIIPGLK
PISTKRQLNIIPHRFHVDLPEDLIKAVDQCKSNVEVRQVGVEWCVQQSKELQAAGIPILH
YYSMGKSDNIKQVAFKVF
>A0A4Z0KUD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriovorax sp. Y22|TrEMBL
MKVIEHIDKATSPLFSFEIVPPPRGKNISAVTDIVKKLLPFNPSWVDVTAHSAGAYYNEK
SDGSVERKIYKKRPGTVGICGVIQNRFKIDTVTHLLTQGFTKEETEDALIELNYLGIHNV
LALRGDALNYNKKYDLSRKRNFYAKDLVEQISDVNKGVYLDDISNSFPLDFCVGVAGYPE
KHFEAPNLATDIHYLKQKVDAGADYIVTQMFFDNSKYFEFVDKCREAGITVPIVPGIKVI
KRMNQFSNVPRHFYVDFPDEFVAEAHENPDHIIEIGINWARKQTEELLNANVPSVHFYVM
NDCDNVSKVLKGLY
>A0A1F5UT59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Firestonebacteria bacterium RIFOXYC2_FULL_39_67|TrEMBL
MRFTEITKMGRFVVTSELGPPKGFHIEKALHEAGVVWPYVHAINVTDNQSSVMRLGGLAM
CKALKEKGIEPVFQVTCRDRNRLALQSDILSAALFGIENLLLLTGDHTTLGDHKDAKPVF
DLDSVSLAYMVKQLEEGKDLAGNALEGEPPRFCKGAVVSPCAEPLDPQLFKMEKKINAGI
EFFQTQAVYEVDKFEKFMKRVKQFGVPVYVGIVVLKGAGMAKFMNENVAGIHVPDNLIEE
LKKDKEKTKSGQTGIEISARLIKDLKPYCQGVHLMPLGWDDKVPKILELSGVKAEKDL
>A0A845RFP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerotruncus colihominis|TrEMBL
MYLYTNDIIHQGGCIVRFDRPYLFDGAFGTYYFSKTGNEAPCELANLTAPQTVLDIHREY
IASGCDALKTNTFAANPVSISDSVRLNEVIAAGWSLAQRAAQESGARVFADIGGICADTA
EMDYLTIVRNFLDLGAHDFLFETLASYQDVRPAVDLIRQSVPDAMVIVSFAVSQDGYSRR
GLYCRTLFDQAESDPCVDAVGLNCSCGPSHMRSLLRALGQRVKPVVAMPNAGYPSSLNGR
VFFEDNADYFAQQLAALYMDGADILGGCCGTTPQHIRRAAAALVAAAARPEGAGWPEPLA
APATGADAPGGGRPGLLHKEIAVELDPPFDYDCSFVLAAASELRACGVDLITVTDSPLSR
TRADSLMTAAKIRREAGIEVMPHISCRDKNHIALRAGLLGAAFEGINRALIVTGDPPMQA
GTRGSDGVYHLSSFDLIAWIHSMNNEVFADAPFLIGGALNVNAVNFGAELARAKKKLSLG
ASMLFTQPIFSDEAVNNFLYARQELKDCRLFAGILPVAGYKNALFLINEVSGIEIPDTVV
RSLEGKTPDEAAAISVAYSAGIMQRVYDAADGFYIMTPLKKVNIVRGLIEEIRRYEQ
>A0A7Y5PTK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MKITDRLTPGKPSFSFEFFPPKTDEGFQQLFQVLQALEPLKPTFVSVTFGAGGSTRTKTV
ELVKRIRSEIGLVAMAHLTCVGLTRDEIGQILDDLQGAGIENVLALRGDPPKGQDHFVRT
EGGFDHASELIAFIRKGWNFAIGAACYPEKHPEALSAQKDLEALKIKVDAGVDFLTTQLF
FDNQVFFRFRDQVHAAGIHVPMIAGIMPILNNKQVQRFAQMCGASIPRELAYRIEAVEDD
EEAVRHIGTFHATLQCLGLLERGVDGIHFYTLNRSTATRAIYQLLRTTPGPA
>A0A7V8VCH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermogemmata fonticola|TrEMBL
MHIRDIFAQHHPTFSFEFFPPKTEEGSEALFRTIAALQELEPSFVSVTYGAGGSTRDRTH
DLVVRIQKETRLTAVSHLTCVCHSREEIAAILGRYARAGVLNILALRGDPPRSMPHYDRS
QDAFRYAAELVRFIREFPEPPDPRGFGIGVAGFPEGHPECPNRLKEMDYLKRKVDAGADY
ICTQLFFDNRDFYDFRERCELAGIRVPIIAGIMPITSRKNLETMAELAAGARFPAKLLRA
VGRCSDDEDVARVGISWATEQCADLLHNQVRGIHFYTLNRSDATVQIYRNLGVKSSRALR
QAI
>A0A7L0YYG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ploceus nigricollis|TrEMBL
MVNETQHACNASSSSRSDGGSSSGSESSKDNSRCSTPVLDTDRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIAYTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDELEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A428JGY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovulum robiginosum|TrEMBL
MSAPRVSFEFFPPQSLEASFRLWETVQALSALKPEFVSVTYGAGGTTRKLTHDAVETIHK
HYKLNVAAHLTCVDASRAETMEIVKSYAEAGVTEIVALRGDPPKGQGSFTPHPDGFSNSC
ELVEALAETGKFKIRVGAYPDPHPEARAKGDDVRWLKRKFEAGADSAITQFFFEAETFFR
FRDACEKEGIDGSRIIPGVLPIEKWGGVRRFAEGCGAHIPDWLDDAFEKAKRDGRETLLG
TAIATELCSELMAGGVQDFHFYTLNKPGLTRDICHALGVQPEAHLEKVA
>A0A521Q253|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp|TrEMBL
MTLNDPAAPLYADLAGDCHVSFEFFPPKTEKMEAQLWSAIETLTPLQPKFVSVTYGAGGS
TRERTHNTVARIARETPLAAAAHLTCVGASKAEISEIADAYWEAGVRHIVALRGDPPEVG
GTFEPHPEGYKGAAELVEGLMQRHPFEISVSAYPEVHPEAASAQSDLDNLKRKLDAGATR
AITQFFFTPDAYFRFLDKILAAGITADIVPGIMPVSNFAATQRMAAMCNTQVPSWMGRLF
EGLDDHPASRQLVSATIAAELCRSLYGGGVRDFHFYTLNRAELSFAICHLLGLRATASNG
GTA
>A0A2E0A4J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium|TrEMBL
MTTLSFEFFPTKSEEGTDKLLAVRDTLAEYNPEFFSVTYGAGGSTRDRTYAIVKAIQERG
IPAAPHLSCVGDSKEDLRQLLNEYKDLGIDRIVALRGDLPSGSGLANSELRYANELVEFI
RAETGDHFTLEVAAYPEMHPQATSFEKDLQNFVRKVKAGADSAITQYFFNADSYFHFVDR
VRAMGVDIPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQQFGEDVV
TDMCRRLLDGGAPGIHFYTLNQAEASLRVWRNLV
>A0A2T1DYA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenomitos frigidus ULC18|TrEMBL
MITFNQLQTLLTAGYFSRLSTFFTALTAGSVGQLAPVSAQPFSRFQTLLTAGHFVVSAEV
TPPRHYKVDAFITSTEKIAACIDIVQVNDNVMAQARLCPLVAAQLMQRSGLEPVVQLTLR
HRNRIALQSDLLGLAALGLRNVVVLGGSSCSIGSDPTAKDATDISTVDAIAALNRLTTQG
QLFNGQIITPPPTFFIGAIATPTTLDLDASMAQLTAKIDSGAKYIQLQATFELETLEQWM
AEVRARGLHQRAHFLASIYPFSCLKALERFSEIPGLSIPESLRARLSHHGSRSECWKINR
ELILGIRAIEGIRGLHLRSLQPRDWLPQISDLLRVPNPVAVDVTAIG
>A0A5F2DLM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira mtsangambouensis|TrEMBL
MNKILLEVIPRDVPTLLSEVSYVKNNFSQISGINIPDLLRFETRSWVAASKIQNIFPNVI
PHLRAIDFDLDHCDHIIEFLQKHNISSVVVIKGDPPTDMSRKVYQTTSTKLIKKLKKEMS
SLKVYAAVDQYRSGIKDEFDYIEMKIDAGADGFLTQPFFDLRLIDIFTEKLRGKEVYIGI
SPVTNEKSQSYWESRNRAYFPKDFQLTMDWNVKFAKEVIGYCSQNDFNTYLMPIRINLEV
YLSGIFK
>A0A0A7PVB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida S12|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRSLLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITHMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A4R0RKC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Steccherinum ochraceum|TrEMBL
MKISKKIEQAVKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
DLTSELVRTCQGLIGIETCMHLTCTNMPAEKVDIALKEAKDHGCRNILALRGDPPMGKDE
WEAVEGGFTHGIDLIQHITKNYGDYFDIAVAGFPQQQTLPPDELAQEIQWLKEKIDAGAT
FIFTQMFYDVELFIAWVKTVRAAGITVPIVPGIAPIQTFNGFIKSTALARTTIPQALMAE
LEPHKNNDEKVREIGTKLVADMCRRILNADIGVRGLHFYTMNLEKGTRMLLEELNLVPRV
EVVKPLPWRQSLTPNRRAETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQSKEEAHKLWGAPTSMAELTALFTRFCSGNLSALPWSDSAPASETSVIVQPLA
KLNELGFLTINSQPAVDGCKSEDRVHGWGPAHGFVYQKARQRRAYLEFFVLPEMLTLLLP
HFERDPNITYYVINKTGDLRTNTLSDGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAY
ELGRQWGNLYEHDSPSRKFILDLMDKALLVNVVHNDFKQPNAIFEPFYKAGAEYQALKAH
KEQTAPVPNGSAH
>A0A7X9HQZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MKVTEHIDKAKETLISFEIIPPKRGGDIKQLLSVLDDIVKYKPPFIDITSHAAEVVYEET
RSGDMKMKVKRKRPGTLGICALIQNKYNIDAVPHVLCSGFTREETEDFLIEIHYLGIDNV
LAIRGDESGYHKPIKFGRSINEYGVDLIKQISDLNHGKYLEDGLLDAYPMDFCIGTSGYP
EKHFEAPNLMTDIKNTKSKIAAGAAYLVTQMFYDNKFYFDYVDLCRQEGINVPIIPGLKI
ITSRSHAHTIPKNFYIDIPSALVEELDKSKPEHAMEIGVEWTFKQVEELLNKKVPAIHFY
VMQNSKPIKMLMKKLGI
>A0A6M0AGR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO4G2|TrEMBL
MTNPTKNSFRTAVESGEFLITAEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQQGIEPICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFEK
KLEAGAEFFQSQLICDFDRLEKFMDQIAAGTNKPILAGIFLLKSAKNAKFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSAINDLVCK
>A0A7T6ZAC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salicibibacter cibi|TrEMBL
MKFLEKLKDEILIGDGAIGTLLYERGYSGSIEDANRRAEEIVVSAHQEYIEAGANVIQSN
TYAANQLKLGNYGLEQETDRINTQGMRLAKQAASGKDVYVAGTIGGIRDGRASSFTNQDI
KEATQSQAEALMAEDPDAILLETYYDLHELIQAVRIIKRLSPDMPVIGNVSLGDVGVLHG
GIPINDALLRLLNEGADVVGINCRMGPAQTIASLEEVSLPEGAYLSAYPNASLPGIQDGR
LVYQSNPDYFKNQAEEFRNQGVRLLGGCCGTTPEHIRSFKDKLQHQAPFVKERAKGSTVR
EQASAEVGNTLRLDKEDPSIIVELDPPKSLTKIDKFIKGAKALHEAGADAVTLADNSLAT
SRIDNLAASTLIKQQAGAHPLLHIACRDRNLIGMQSHLLGLHALGIRDVLAVTGDPTKVG
DFPGASSVYDLTSFDLIRLIKSMNEGFSHSGRPLGLQTQFTVGAAFNPNVSSMDKAVKRL
EKKIVAGADFVMTQPIYDVETLQRLKEASAHLDIPIYIGIMPLINERNAEFLHNEVPGIQ
LTEQVRKRMAACKGDVQKGEEEGLAIAKELLEASLDLFGRLYLITPFLRYHITAALTNDV
KARSFNV
>A0A3D3FRH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MSHPLIDLLAGGTVVFDGAMGTELYKRNHFVNICFDELSLRDPKVVREVHEASRKAGADV
LTTNSFGANRYKLADYLLAERTKEIAAAAARIAREVAGRELLVAGSVGPLGRHASGGALS
PHEAVDAFAEAIVALMEGGADFILFETFARSRDLGFAVEAARGLGAPYLPCMAFGDIASS
LGGESIDEFFAPCLGAGAGAAAPLMLGFNCSVGPKQMLDNLQDFVPRSTLPVLAMPNAGA
PQRINDRMFYMTSPEYFASYAKRFAELGVKAVGGCCGTGPEHIAEAARALKALDRAGAAG
VAGVAGAVSLEVVGGAAPVECAPLAQRSAFGRALAEGRWVTSVEIVPPTGWDLAKTVERA
KRCAEAGVHAINIPDGPRASARVSPMITSQRIQAEAGIEAVLHVTCRDRNLIGVQSDLLG
CAAAGINNLLIITGDPPKLGDYPYATAVFDLDSIGLVRVAQRLNVGLDIGGKPVAPPTRF
VLGVGADPTNLDQEREIERFFRKAEAGAEYAITQPVYDPEALIAYIERVRFTGVRIIAGI
WPLASYNNALFLNNEVPGVSIPESIMERMRKAGDKESARRVGIETAREILDAVRPYVAGV
QVSAPFGNVETALAVLAEE
>A0A3E2DGH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cutibacterium avidum|TrEMBL
MQTQKPTIADLLAAGDRPLHSFEFMPPRSEDDVYRLWSATDALVPMAPDFISVTYGANGS
RRDRTLRCTQHMVSTGLRTVGHLTCVVQSVSDLEQMVADYAESGVNHILAVRGDMPGGAG
QPWVAHPEGLPNATELVRLVKRVHPEACVGVGAFPDGHPESADIDLDARILVDKAEAGAS
FAITQLFFLPSHYQRLVDRVRAMGCDIPIIPGIMPITSYGQIRRFAELSGTDVPAELVAR
IEAVKEDKAAVRRIGLEAAVDMCCELLDSGAPGLHYYTLNRSRATTELRTMLARRRPQLA
GLPADFEATPAA
>A0A430JCE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus whitsoniae|TrEMBL
MKTDLRSALQQEIITGDGAMGTYLYQMGFPVGISYEELNLLRPETVSEVHRRYYEAGARL
IETNTFSANREKLSKYGLESDVEAINRAGVELARKAVGDNAYVVGAIGSIRAGKRKNVRT
ADVEAALREQIGILLDSPVDGLLLETFYDLEELQLALSIIRSMSALPVICQFANEGTGST
QDGVPLQEAFLRLRDGGADVIGFNCRVGPNGILRSMEKLPSDLGVPFSAFPNAGLPDYVD
GQYTYAATPKYFAECARRFADLGARLIGGCCGTTPEHIAAVAKALQGYVPAAPGTTEGAP
TEVVRVSEPAPAQPAPPAAPTLLDIVKQRKTVIVELDPPKDLDIQKFMQGSKALQDAHVD
AITMADNSLAVTRMSNLALGYLVQDKLGARPLIHIACRDRNMIGTQSHLMGLHALGIDHV
LAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKSNFVIGAAFNPN
VKHLDKAVQRLERKIEAGADYIMTQPVYDAKLIEDIYETTKHLNVPIFIGFMPLASEGNA
EYLHNEVPGIRLSDDVRRRMSGLKGPEGRAMGVEIAKELLDTAMQYFNGIYLMTPFLAYE
MCVDLTKYVWEKSNRHDFHLYPLSK
>E4SH95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldicellulosiruptor kronotskyensis (strain DSM 18902 / VKM B-2412 / 2002)|TrEMBL
MKKNFREFLKEQAIVIFDGAMGTQLLLRGFSVDFPLEWANVANPELVKQIHTDYILAGAT
CVETNTFGANECKLKVFGFENEVERINRSAVRIAKEVAENKVYVIGSVGPLGKPVGNGFE
IDDKKAKDVYKRQLYFLLDEGVDAIIFETAASTHEVQIAIEALKELNDEIPYIIQFSFTK
ELSTVYGEDIYRVIEFLKYTDADVVGLNCGNGPQKTLEALKIFSQHLKGPFSVQPNAGYP
QLIQGRPVFSTSANYFASFVPEYLKLGAKIVGGCCGTGPEHIKAVKEKIKEVSPSLEIEV
VERKEEQKAVLKDTPSELSQKLGKKFIFTVEISPPKGIELEKTKEGVKLLKEAGADTVNI
ADSPMARVRISPIALAHILKEELGMESILHFTCRDRNLISLQSELLGAAALGVKNVLALT
GDPPSIGDHPQAKPVFDVNSEGLVLILSRLNNGTDYMGNPIGKATNFTIGVALNLNADDL
GKEIEKLKHKIENGAHFIETQPIYEPETLEKFFEKVDFKLPPILGGILPLRSPRHAEFLH
NEVPGITIPDKIRERMRSSKEPAKEGVEIACEIVEKIKHMVSGIYIMPPFEKYEMAVEII
RNFKI
>A0A7H4K961|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oricola sp|TrEMBL
MTGSVFSRTQRVALNDDIRVSFEFFPPKNEAMAATLADTIEKLAPLNADFVSVTYGAGGS
TREPTQRTLAHVQKQGGMDAAAHITCVGSTRDETDVVIREFAAMGIRRFVALRGDPQTGM
GTRYVPHPGGYENAAHLVAGLKAFGDFDISVAAYPEKHPESPDFATDIDMLKRKVDNGAA
RAITQFFFDNDGYERFVERVRRAGIYVPIVPGILPIHNFRAVSNFAGRCKTHIPAWLAER
FEGLENDPQTHALIASAIAAEQVLDLVDRGVRDFHFYTMNRPDLVFAVCRLIGVREEHVD
AAA
>A0A7Y1T4Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
MTVQHPSPLFEHTAGDVEVSFEFFPPKTDKAQEKLWSVIGELAPLGPRFVSVTYGAGGST
RERTHETVKRIVEETPLTPAAHLTCVNASRDEVQDIARAYWDAGVRHIVALRGDPPDGER
FTPHPDGYANAAELVAGLKEVADFDISVAAYPETHPEAQSSDSDIDHLLRKIDAGANRAI
TQFFFRPDAFFDLQEKVAARGRQVELVPGILPVTNVARTRQFAQQCGTAIPDWMDKKFEG
LDDVPRARDLIAATAAAELCGRLYAGGVRHFHFYTLNRAALSWAICHMLGVKR
>A0A353S7C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MTIKHILDEKRVTLSLEVFPPKQQSNFDSVLKAAKELSSLKPDFMSITYGAGGSTRGNTV
EVAAGIQESGTPALAHLTCVGNTRADIAAAAALMKQHGIENVLALRGDRPQGFTGEKATV
DGLDHASDLVRLLKQEGFCVGGACYPEGHPESANRSEDIDMLKFKVDAGVDFLTTQMFFD
NNMLYSYLYRLQSKGIHVPVLAGIMPITSSQQVERMVKLSSAYIPAKLLSICDRFEDKPD
AMRQAGIAYAVDQIIDLISNGVRGIHIYTMNKPSVARDILGCVDAIVAASNCR
>A0A520DBT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
MTISVNQLEEAQIALKAPLYADVAGDIDVSFEFFPPKNEKMEEQLWDAVRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATKAEIDSVAEEYWAAGVRHIVA
LRGDPPAAGAKFASHPGGYENAAALVAGLKRLHPFEISVAAYPERHPDSPDMAADIDNLK
AKFDAGATRAITQFFHEPETFFRYRDRLAAAGIDAEIVPGIMPVTNFASVVRMSKMCGTE
VPAWMARLFDGLEDHPASRQLIAATLAAELSRKLYAGGVKSLHFYTLNRAELAFAICHLL
GVRSKPVANVAAA
>A0A356JZ01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
MTISKILEQKKTLLSFEVFPPKQQANFENTVNAAKELCNLNPDFISVTYGAGGTTRENTV
EIASKILSFGTPVLAHLTCVGNTIDEAKNIISQMKKNKIENVLALRGDIPQGISNPLSKE
LEHANVLAKILKDEGFCVGGACYPEGHPESHNRQEDIDNLKYKIDAGVDFLTTQMFFDNN
MLYSYLYQIQSKGIHVPVFAGIMPITNSNQVSKMVKLSSAYIPAKLLSICDRFSENPEAM
RQAGIAYATDQIIDLISNGVRGIHIYTMNKPSVAQEIYKNVDKIISATNS
>A0A326GL37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp|TrEMBL
MTPTISDLEEARRALDAPLFADLAGDCAVSFEFFPPKTEKMEAALWETVRALEPLAPKFV
SVTYGAGGSTRERTHATVARIARETSMPAAAHLTCVEASRAEIDQVAQEYWAAGVRHIVA
LRGDPPTMGQKFVAHPDGYENAAALVAGLQKLHPFEISVAAYPECHPDSEHQAADLDNLR
AKIDAGATRAITQFFFTPEAFFRFRDAAAAAGINADLVPGILPVSNVAQVRKFAGLCGAS
IPAWMDRLFEGLDDHPGARQLVAATVAAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLM
GLRPKATPVAAAA
>V9V8U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas monteilii SB3101|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLAAYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1F4T7D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-1 bacterium RIFOXYC12_FULL_54_18|TrEMBL
MKVSKDLNRTDRPTLSFEFFPPKTPVGEEHLIEAIEKLGKFSPDFVSVTYGAMGTTREKT
FYWAEQIKKKFKIEPVAHLTCVGAERKDIAAQLKQLADLGIENILALRGDPPSGETKFVP
PKNGFRYASELVEFIKEEQPKFCVGVAGYPEKHTEATAIKKDIANLKKKIDAGAEYVITQ
LFFNNQAYFDFVDQCLAAGIKVPIIPGQMMITSTKQIKTLTEKCGATIPKELLEKIEKNA
ENPDAIKRISTEWTLEQTRELIIGGVNYFHFFVMNQAEPISTVLSELGF
>A0A1W2CD90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. B1|TrEMBL
MAKASIIHPNWDKTPDGITDGFSLEMTAKDEASLRDASPLIPAETPIAVTFLPGEDVGAR
VAATIAVRELGFEPMPHFSARRITSEDDFEGYLRAVVEQAGVTRCFIVAGDPPEPVGPYF
DTSALIATGAFERSGIKAIGIGGHPEGHPNMSEAECWAVLEKKVAEITARGMAPLIVTQF
GFDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVT
NLLGTAGPDKLVDAFAKGLGPEHGKVRLHFYPFGGLTKTLEWIHGYNRKHGIGQGA
>A0A0Q7QN70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium sp. Root495|TrEMBL
MPVEDPTITALLAETGPSYSFEFFPPKDDAGEEVLWRTIAELEPLQPTFVSVTYGAGGTS
QERTVRVTERIASESRIKAVGHLTLVGQSRDEIAEVLRQYAAAGIDHVLALRGDPKGGPR
APWETHPGGMEYAIDLVRLAHEIGGFTVGVAAFPEGHPDADDLDHDARVLVEKVQAGAEF
AITQMFFRSSDYFGLVERVRELGCDAPIVPGIMPILNFPQVARMAELSGAAMPQEVLDVI
EPVADDPVAVRARGIELATQLCRDLLAGGAPGLHFITLNRSKATREIFEQLRSEDLI
>A0A561XXN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax delafieldii|TrEMBL
MNAAHAQGTGFPVSFEFFPPKTPEGADKLRVARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILSEGVGAASHFSCIGATRQSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLQAYVTKVRAGADSAITQYFYNSD
AYFRFVEDAHQLGADVPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A7U7KI51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novacetimonas hansenii|TrEMBL
MQVSVELIPRDTETLLRDAAEVRSCFPLADMINIPDLLRFPLRSWDAAALARPHFPNVIP
HIRAIDIAPDAPLPGVGQEGLEAVLVVQGDPPSDLRHLTYPNTTESIIRRYRAEAPHLAV
YAAFDPYRRAPYREMEAIARKKEAGAVGFFTQPIFDMRMLDLCMNWLHGENVFWGISPVV
GPRSRSYWETTNHVIFPHDFEPTMEANIAFARQMMRTVRTQGGNVYLMPLRVNLQRYLVP
LCGV
>A0A6P4GDY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila takahashii|TrEMBL
MTTAGSFCRSASERVLPNSMHAIQVPAGGPSNAAAPTSYLPCVTFAPGQIKAAVGEQRIG
PLVAERTARQRFFYGIEVTASGANGRPTCLDFNQFLPLLPTFVSVVWLGQRYWDVEPVGE
VESLQLAQHLATHIPVLPHLSAYRLENERLDQFLALNFSSLLAVRGDQVHEGQTFRISLP
MVEQSRRQRGEKISICVPGYPEGYTSLGDFPQNSTRNMEYLKAKIDAGADCIITQICYRP
EVIVQFVKHCRAAGITVPILVGLITPESFRSYSRMEQIAGVYLPSDLSEELVQLQSPQEG
DTKPDQDLTKQFFISLTVRIVRHVLDADVGVWGFHFFTLNRFRPVQAVLKELRELHLLKD
PDQA
>A0A5T7KXY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enteritidis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGQPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1Q7LKL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenarchaeota archaeon 13_1_40CM_3_53_5|TrEMBL
MTKEDLSSLNGRVDAITIPALRNGNHDSSYPVTFNVSPQQRSLASAVLTRGAGIETVPTL
TCRDCREEDVVKVQGLLLKGLENILVLYGDPFSDRERDKYEFAKTADLIRRVVDSANGKR
PSIGATTNQYAQDTESEVLRALTKVEAGADFVITNMSFDSEKVLDHRDALLSAGLNVPLF
IQVSIPASLNNIVYVTQKFGIPLPAPVMRRLSADGLQVGVELAGEAFEKLEDEAEGIHFS
YLLRRKSPVTAYLRLLDRIGRRRTVLAAPVFDIPGQVLGS
>A0A257SII4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus ferrivorans|TrEMBL
STRERTFATVTMIRQDYDLEAVPHLSCIGSTEAGIREILEDYQKQGIRRIVALRGDLPEG
MENPGHFQHAADLVAFIRHFGGFDVYVAGYPEIHPRATSARDDVAHLVAKVQAGADAIIT
QYFFNPDAYLQLRDELQRQGVEVPVVVGVMPITNFEQISRFSAMCGADIPQYVRRRMEAY
ADDLQSQYQLGIDLLSRQCQLLLREGAPSLHFYTLNQAEATAAIWRNLGL
>A0A1Z4G513|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix sp. NIES-2098|TrEMBL
MSDTQSKTVLNAFRRAAQAGEFLVTAEVAPPKGGDPTHMLQMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQQGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPNAKGVFDLEAVRLLQLIRKMNQGFDCNEQLLTDGALDLFTGAAVDPQCASWSGLQS
RFERKIEAGAQFFQSQLITDFDRLEKFMDTIASGYKKPILAGIFLLKSAKNAQFINKCVP
GVNIPQHIIDRLAQAKHPLEEGVKIAAEQVQIARQLCHGVHMMAVKREDLIPQILDLAGV
TPVNLVGVK
>A0A506RJC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aestuariibacter sp. GS-14|TrEMBL
MVSYAQGVDALNQSLSELRDIDVSFEFFPPKTESMEKTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDIVKRIQQQTGVTAAPHLTCVDATKDELKQIAKDYWDSGIRRIVALRGDLP
PGVDKTDMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDASVYLRFRDRAAAAGIDLDIVPGILPVTNYQTLVKFAGFTNVHVPGYLHKMFDGL
DDDDQTTRNLLGANIAMDMVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRANNN
>A0A257SMR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus ferrivorans|TrEMBL
MAHSVEFFPPKNAAGEERLREAITALLPLGPEYASVTFGAGGSTRERTFATVTMIRQDYD
LEAVPHLSCIGST
>A0A2N7LE85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterovibrio norvegicus|TrEMBL
MGYSHASHLDALNQNLTDLNGDINVSFEFFPPSSESMEQTLWASVQRLKTLQPKFVSVTY
GANSGERDRTHSIVKSIKQETGIEAAPHLTCIDASRDELKTIARDYWDSGIRHIVALRGD
LPEKSAKPDMYAADLVELLKGEADFDISVAAYPEVHPEARSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIIPGILPVSNFKQASRFANMTNVRIPGWMANQFE
GLDDDPVTRQMVGASQAIDMIRVLSREGVKDFHFYTLNRAEHTYALCHTLGVRPKA
>A0A2Z5A764|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas oryzihabitans|TrEMBL
MKPSLSFEFFPCKTEAGHEKLIATARQLASHGPEFFSCTYGAGGSTRDGTYRTVRQLNDE
VGVPTAPHLSCVGDSKAKLRELLQQYREAGINRIVALRGDLPSGMGLSGGGELRHASDLV
AFIRAETGDHFHIEVAAYPETHPQARSFTDDVRNFVYKMEAGADRAVTQYFFNADGYFHF
VERVRKLGVEAPVIPGIMPITNYSKLARFSDACGAELPRWLRKQLEAYGDDTQSIQAFGE
EVMTDLCGRLLEGGAPGVHFYTLNQAEPCIAIWRNLGF
>A0A7Y8FX94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas reactans|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGDHFHIEVAAYPEMHPQAHSFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVITNMCEDLLNGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A7X3VHL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriia bacterium|TrEMBL
MRISDILRTDRRAVSFEFFPPKDDAGFASLFETIEALKGLDPSYVSVTYGAGGSTRRKTV
ELVKRIKHEIGIESMAHLTCVGANRDEIGGVLDDLAAAGLENVLPLRGDPPKGESEFVPT
PGGFRYANELVAFIRERHSFCLGGACYPEKHPEAPSAEADLDNLKRKVDAGVDFLITQLF
FDNDDYLRFRERAVAAGVRVPILAGIMPILNVKQIKRFTRMCGASLPNALRQKIEAVEDD
AEAVRQVGIYHATRQCEDLLRDGVPGIHFYTLNRSTATRAIYQSIKGLLANKPAA
>A0A1S8ND67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium saccharobutylicum|TrEMBL
MIREYLKKNILICDGAMGTYYSELTGNDITYCEFGNINNKDIIKRIHEEYINAGAKLIRT
NTFSANRYDLGISFDKLKDIITSGINIAKEVTENTYVFIGASIGPIREESIDECDSDILD
EYKFIVDCFIENNIDIFIFETLSNYNYLKEICRYIKSKNPNSFILTQFAVKPDGFTRDGL
SVTKIINNVKGINEIDAYGFNCGSGPTHIYDIIKKINIDGDIVSALPNAGYPEIIHERTV
YPNNPIYFAQKVNKIKSLGTSIIGGCCGTNPVYIKELANLINKNVNVVNTLTKNEEETNK
LENNQENSFKNKLDNNEFVIAIELSAPINTDISKLMQGAKLCKENNIDLVTIPDSPMSRV
KAESTIISAKIKREIGIEAMPHICCRDKNINAIRSGLIGAHIENIRNVLAITGDPISDAS
KVETKSVFNLNSFKLIELIDDMNSEVFNNDNILIGGALNLNVLNKEVEFNRMMKKIEKGA
NFFLTQPIYDEHAIEFLKKIKERTNVKILGGLLPIVSYRNAMFLNNELPGVTIPEKYINM
FSEDMTKEEGQQVGIDIAVEIGRKLKGLCDGLYFVTPFNRVNMLIEIINKIKG
>A0A7K7VGJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eudromia elegans|TrEMBL
MVNENQHTCSASSSSRSDGSSSGSESSKDSSRCSTPVLDAERHERLREKMRRRQDSGDKW
FSLEFFPPRTAGGAVNLISRFDRMGVGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLETILHMTCCSQTKDEITGHLQKAKRLGLKNIMALRGDPADEEWQEEVEGFNYAVDLV
KHIRNEFDDYFDICVAGYPKGHPEAKNYEADLRHLKEKVLAGADFIITQLFFRSETFLKF
MKDCQTIGINCPIVPGIFPIQGYHSLRQLVRLSKLEVPQEIKDVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELTSEESVFEVFTCYITGEPNKNGHRVTCMPWNDDPLATETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALRKVLKKYETRVNYH
IVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLFWKDEAFALWIEQWAKLY
EEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6H1N3A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S1D4-11|TrEMBL
MALGSASTRTDRARTVRDMLATGKATYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDVDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCTTPVIPEVMPVTSVKMLERLPKLSNASF
PDVLKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A7C6H467|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MKNMRTTRLSADAVRKPIICDGAFGTYFRSLYPDNGTPELANLDYPDRVVAIHRAYIDSG
ANLIRTNTFGLSAMLSNPSHEMIDRIAELQIAAVDAARSAVSSGHHVFIAGNIGPVARPM
RHSRRENDVSGDPVEIYVRQAEIFIHAGVDLLWFESFSSVDAIISTVQRIRESSDCHIQV
QLASDPYGFTEDGLLVASLMNRLAAEDSIDGVGLNCGIAPGLMMNVFKRMQRPRNKIFSL
IPNAGFPAFARDVAAAEENIQFFAQKLSEALPLGVHIFGGCCGTTPDYIRALSESIHSQV
CSADASDRTEPMGDNHSEEISSDLGASGAARQSSLSKKLIAAELAPPFNADINRLMEAAA
DYKKIGVDMITFPDSPSGRTRVDSIAMAIKVFRDFGIESVPHICCRDKNSIGLSAQLLGA
YVNNLRRFLVVTGDKVPIELRHTTQAVFDFDSVGMMQVMSEMNRNDFASDPIVYGGALNC
GRRNIEVEIRRVLRKMQAGATFFITQPIFEAREIENLRRVKAETGAQILCGLMILVSKKN
ALFIKNEVPGIPVTDAILDRFDLLSDPLDRSAAEAVGVLMCREVVEKTLEFVDGYYFSIP
FFRSYLLRDVLAGFQLTEGDVLPP
>A0A847GI70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedens sp|TrEMBL
MTQAPLSLQEVYKTGRPAISFELFPPKTEEGVASLFEHLKELVLCKPAYITCTYGAGGST
RQRTLDILSEVHARHPRIPVASHLTCVGSSRDDLRAYLRAAVAAGVDRVVALRGDPPKGA
DAFESATDGLRHANELVELLRAEFPALGVIVAGYPETHPEAPSLAKDIENLKRKVDAGAD
AVITQLFFDNLDYFRFRDRCEEAGITVPIVPGILPVTNLAQAKRMTALCGTHMSPKLVKR
LEVHGDDEEGQYAVGVYHAARQAEELIAQGAPGIHFYVLNKSRAAALICRALALFTPVD
>A0A7X6VCB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MRISELYNNKRKTIAFEIFPPRPEMPMDSLFSSIEGFKKLSPDYISVTYGAGGSQRGRTV
EIASKLKNNYGIEAMCHLTCAGHSVEEIDELLETIKKENISNILALRGDPPINQPDFDFN
KGAFKNADELITHIKKTDDFCIAAAAYLEGHSDSKRLSEDRRYLKQKVDAGVDILVTQLF
FDIRLYFDFLDRCAQMNINCPVIPGIMPIFNARIKTMTARSGCSIPANLVLMIDKYQDSP
EDLKKAG
>J8HCX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VD115|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKVSVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIQSMKRAVANVTPVIDKDTIQRPKVVH
THEKRSKAQVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVVLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2S3ZKD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium zongtaii|TrEMBL
MTATPTTPPADPDCRSSIPFSFELYPPKTDAATTALHATIDALAAARPKFISVTYGASGS
SRTSSLDVLRYIRRATIVDPMAHLTCVGSSHAEASSLIREFLDAGVSSFLALRGDPPEGL
TENDAFLGDLHSAGELVQLIHRVQAERVPYQETPIPGLPRARAVKTEREHVRIAVAAFPN
GHPRSRSTAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPV
TSPGRLRRILELSGEELPAELSIQLEVEPTLEGQREIGVSHAAALAEKLIAGGAPGLHLY
AFNQHETVLAVLDRAGALAPAQPVVSAHNPPPTHPSTSPADTRAGIHSTKDHY
>A0A2W5KFQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Starkeya novella|TrEMBL
MPNDRLSRAARRPIRVSFEFFPPKTPEMEETMWRSIRRLAPLHPTFMSVTYGAGGSTRER
THATVERMVKETDVPPAAHLTCVSATKAEVDAVVDGYREAGVRHIVALRGDPAGGVGATF
EAHPEGYQSTADLVAGIRRRAPEIELSVSAYPEMHPESPNRDADFDTLKAKVDAGANRAI
TQFFFDNGHYLRYVDEARKRGIHVPIVPGIVAVSNFRQTANFAQKAGASVPAWFAERFEG
LENDPQTRQLIAAAVAAEQVLDLVDHGVKDFHFYTMNKADLVYAVCHLLGLRPSAQAESS
AAA
>D0BNA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulicatella elegans ATCC 700633|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISSLQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHIPRKFKAILDKYEHDPESLRAA
GLTYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1B4S4E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. MSMB617WGS|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVE
DAAKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKIVCERLGL
>Q0BVP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)|TrEMBL
MTTPTGFSLPARGDGWRQRDMNRLAGQEQQGESATLRRWLTGPRVTGLPAMDAEHPVPLL
SFEFFPPKTEALERQLWACIRRLEPLGPRFVSVTYGAGGSTQARTHETVARIVRETSLTP
AAHLTCVGATRDEVDEVARHYWEAGVRHIVALRGDMPGGAPYQPHPGGYAYASDLVAGLK
RIGDFEISVAAYPETHPAAPDAGFDLDNLKRKLDAGATRAITQYFFDTDTFLRFLDRCLV
AGITAPIVPGIMPVSNYAQAVRFSTAIGTSVPDWLGRLFDGLEDDVETRRMVAAVVAAEQ
VRLLQANGIDEFHFYTLNRPDLVYAIARILGVHPPAAPIA
>A0A556U227|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bagarius yarrelli|TrEMBL
MVNQREETGCRSFKCDSSGASNSGESSKESSRCSTPVGESDRCNRLRDKIKRRIESGDRW
FSLEFFPPRTAGGAVNLISRFDHMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCKQTKEKLTFYLNKAKHLGLKNIMALRGDPVGADWEEEEEGFNYAVDLV
KHIRSEFDDYFDICVAGYPTGHPEAESYEDDLKRLKEKVDAGAHFVVTQLFFRAETFLKF
LKDCRAIGITCPILPGIFPLQGYHSLRQLVKLSKLEVPEEIMKVIEPIKDNDAAIRNYGI
QQAVEMCKVLLNSGDVPGLHFYTLNREVATIEVLRQLGLWIEDPRRRLPWAVSAHPKRKM
EDVRPIFWSTRSKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLK
MWGEELINEQSVYEVFTNYIAAQPNQNGHKVICLPWNDDPLAPETNMLKDALAKVNRRGI
LTINSQPNINGKPSSDPVVGWGPPGGYVFQKAYLEFFTSSENVNALLKVLKTYEPRANYH
IVNVRGENITNAPDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWGKLY
EDESPSRMIIQYIHDNYYLVNLVDNDFPLDSCLWQIIDDMFQLLDTPGEHLEENVQ
>A0A1Y4RF03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp. An138|TrEMBL
MKITELFERGEFVVSAEVGPPKGFHVEHLLEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKALKDEGLNPIFQLACRDRNRIALESDLLSAAMFGIDNILCLTGDHTKLGDHPQAKPVF
DLDSVSLLHAVTKLEEGEDLGGNKLVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQLGIIIPKSAGMVKFMNNNVAGIHVPDEMIEE
LKADPEKAKAGITGVEIAARIIKECKPYCQGVHIMALGWESKVPALLEAAGL
>A0A015M0X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizophagus irregularis (strain DAOM 197198w)|TrEMBL
MKVINKILKAHEEGRPSWSFEYFPPKTQQGVQNLYDRMERMYRLGPEFIDVTWNAGGTTS
QLTSEIVATAQSVYGLETIMHLTCTNMPKEKVDKALKDAKECGCQNILALRGDPPRGQEH
WEACENGFSHAIDLVRYIRQQYGDYFGIAVAGYCEGHVDNPDKDDDLYRLKEKVDAGADF
IITQVFYDVDIFLNWVKKCRAIGISCPIIPGILPIQNYSGFNRIITLSKTIVPQFVLEEL
EPIKDDDAAVKEYGIRLAVDMIRKMFADGIKCYHFYTMNLERSTRLILEALEFVPPIENV
KPLPWCPSLSAKRKKENVRPIFWRNRTKSYIARTEAWDEFPNGRWGDSRSPAFGELDGYG
VSLKHSKKGALELWGYPQKHSDIFDVFVQYCRGEVNSLPWSDQPLAEESNIIREQLAHIN
SLGYLTINSQPAVNGVRSDHKIFGWGPKNGYVYQKAYLEVFISPTQLDALIARIERDTNI
TYYAVNKQGDLKTNTQSDGPNAVTWGVFPGKEIIQPTIVEAVSFTAWKDEAFELWNEWTK
IYDTDSISAKLITDIADN
>A0A1Q7CJ54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium 13_2_20CM_2_66_6|TrEMBL
MRIVDMLTRSRPSVSFEFMAPRDESEVDVLERTISALAGHGPDWVSVTYRQRTGEKTLEL
VTRIKRQYHIEAMAHLTCANTVDRTRQVLNWMEREGVANVLTLRGDPPSAGEPFVPADPR
LTHASDLITLVRGSGYRFGLGAACSTERHPESPDLEHEFRYMQLKVEAGAHFLITQLFFD
NRFYFDLVARARAAGIKVPIVPGLMPVPSRRSLAVMTAMSGATVPAALQAEIDGAADDDA
IRALGVRHCIAQCAELLEGGVPGLHFYTFNRARAPIEILAALRGQQLLAS
>A0A239XPZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium taklimakanense|TrEMBL
MKITDHIKKANGKTLFSLEVIPPTKGTGIEDLYKNIDPLMEFKPPFIDVTTSREEYVYIE
KGNGLMERKITRMRPGTLGICASIQHKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
VMALRGDAMKGQNQFLPTEGGHHHAIDLVHHINDIGRGKYLTDEKRCEEENKFCIGVAGY
PEKHIEAPSMNYDLQKLKEKVEAGADYVVTQMFFDNQKYFNFVKEAREIGIEIPIIPGIK
PIATKGHLSMLPKTFKIDLPEELISEITKAKDNTAVKQIGIEWAVKQCRELLNFGVPVLH
FYSMGKSDNIRKVASQLF
>A0A0U3SRG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces variabilis|TrEMBL
MSALGDLISADEPTFSFEFFPPRTEAGQRSLLRAIRRIEALTPSFVSVTYGAGGSSRDRT
VEVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGIRDVLVLRGDPPGSPRGPWT
PHPQGFDYAHQLVSLVRGLGDFSVGVAAFPECHPRSPDRDSDIRHFVAKCRAGADYAITQ
MFFHVEDYLRFRDRVEAAGCETPIIPGIMPATDVRQIRRFSELSDAAFPEDLAHRLEAAR
QDPGTAHRIGVEYATGMALRLLAEGAPGLHYITLNRSDAAADIHRNVMSARSSDVLSGHR
>A0A1B7HII5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buttiauxella noackiae ATCC 51607|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASPDELRTIAQDYWNSGIRHIVALRGD
LPPGGGKPDMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDVEIVPGILPVSNYKQAHKFATMTNVRVPHWMAQMFE
GLDNDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPLV
>A0A1B8EVS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. 05NY08|TrEMBL
MHIKDMLNQGEQAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHA
QLTCEMVSVAQSVYGLETCMHLTCTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEK
WVATDEGFQYARDLVKYIRKTYGNHFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATF
IVTQMFYDVPNFLDWVRKVRAKGITIPIIPGIMPISTYASFLRRCNHMNAKIPTGWIEAM
EPVKNDDAAVREIGRGLVTDMCRSILESGINHLHFYTMNLAQATRSVLEQLEMLPSEERP
LKQALPWRQSLGLGRRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGEPKSVKDIANVFLRYLNADIESLPWSEAPISNEADVIKNQLVE
LNERGLLTINSQPAVDGVKSSHPVYGWGPVNGYVYQKAYLELLVAPELIDKLLDRIARDP
EVTYYAVTKSGTLRTNAPSDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHDASSPSRNVIQRVMETFYLVNIVHNDFHQRDALFSLFEGLTVPNIDKAAEGTAAPA
TAPAPAAAAAPATNGDKVKDGAPAIVSNVLPVA
>A0A212TLS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 2114.4|TrEMBL
MRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSVTYGAGGTSRDGTVRA
TERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALRGDPPGDPMGEWVKHP
DGIGYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVAKCRAGADFAITQMFF
YPEDYLRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAFPPELAERILAVKDDP
AAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLGLHQQS
>G0M0V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus pentosus IG1|TrEMBL
MNLRQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHQSYIQAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVRIAVTAREHADHPVYILGTIGGLAGDTDAAVQR
ATQAEIAANVTEQLTALLATEQLDGILLETYYDLSELLAVLKIVKAHTDLPVITNVSMLA
AGVLRNGTSFTDAIVQLHAAGADVIGTNCRLGPYYLAQSFENLAIPADVKLAVYPNSGLP
GTDQDGAIVYDGEPSYFEEYAERFRQLGLSIIGGCCGTTPLHTAATVRGLSSRSLVPHNA
PTHVAQAPTLVTTKSQHRFLHKVVTEKTVLVELDPPRDFDTRKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTAIAAQLKLNYGITPIVHLTTRDHNLIGLQSEIMGLHSLGIEDILAV
TGDPAKLGDFPGATSVGDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TDVSTKSISRKLSYGCDYIITQPVYDLANVDALADALAANQIDVPVFVGVMPLVSRRNAE
FLHHEVHGIRLPKSVLERMQQAELDGNERAVGITIAKELIDGICARFNGVHIVTPFNRFK
TVLELVNYVQQKNLTKVQ
>A0A2C5YZ57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps australis|TrEMBL
MRPLHLTASLLALSTTTASNTSADKITHKIASAAHDFVSLEFFPPKTPSGFTSLQSRVIR
INEALQPLFVSVTWGAGGSAAQDSLRLGGMLQRDLGITTLLHVTCRGMTRRRLDETLRRA
RELGIRNILALKGDVPRDDGDADEASGSGEGSGEFIWAADLVRYIRRTHGGFFCIGVAGY
PEGHFNASDAASRSVEHDVPYLVDKVSAGSDFIMTQIFFNASVFSAYRERLSAHPVLRSI
PVVPLFLAIPDACATGWCEGE
>A0A7J4FZ42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeales archaeon|TrEMBL
MSKLSENLGKKFIVTGEVAPPRGTDLKEFYHEVEEFRKLMPKLYGVNVVDIPGSRLLMSS
LAASIILIQNRIEPIYQLTCRDRNMLALQADLLGASAFEIENVLALTGDHPACSSSDHPT
AKPVFDLDSATLIKTMKLMNSGTSITGKELNKPTNFFIGAALAPGATPVDGEIYKTKRKI
NAGVDFFQTQAVFESSVMQSFLDKYEKTFKEEVNSRVLIGIVPLYNYGMVQFLRTMPGIT
ISENTGNRVKNAKDPVEEGVNISAELIDRVKEMDIAGVHIMPAGKIEALVKLLDLI
>K8NY78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afipia broomeae ATCC 49717|TrEMBL
MTSEATAPAGSQGQKRPAISFEFFPPKTEEMERNLWEVINRLAPLTPNFVSVTYGAGGST
RERTHSTIARILSETKLTPAAHLTCVDATKADIDDVVARYHDVGVRHIVALRGDPVSGIG
NAYTAHPEGYQSSADLVASIKRHHPDMEVSVSAYPEKHPESATLEADIDALKAKVDAGAT
RAITQFFFDNDLYFRYLDRVRAAGITIPIVPGILPVQNFKMASNFAKRAGATMPEWLSAK
FEGLDDDADTRRLVAATVAAGQVQKLAKHGVENFHFYTMNRADLVFAISHLLGIRPNGAQ
KAA
>A0A2D5P7A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp|TrEMBL
MFETLLQKLQEDYYLTLETTPQHEPSMHNIIERIKKFKLQNKVDGFSCTDNPLAKLKYNA
LFASLKLQMEFEKPVIATMSMRDRNKIALQSDLLGASDFDVRAILALTGDPAKMSDQPHS
KGVFEANSIMLLKIIKSFNYGMDFAGHPFKIEPKQIFPFSVVNSYAKNFSSLEKKMHNKI
QNGSLGIISQPVFDIDNAKKLLESFDKAKADVEGDKKKSQLIFGLFPITKLRTALFLSAQ
VPGIHVPQMWIDKLESAHKISVEEEYKVGMQLSQDIYKEIRKIHPKVHLMTANKFDVANE
IIS
>A0A396N736|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM42-36|TrEMBL
MIQEKEHKGIVFSCEVFPPKRDDDIYQIYKTLDEIKTLKPDFISVTYGAGGSNSKKTATI
AAYIQNICEVEALAHMTAVGMDEASLRALLFELKKKGVENILALRGDKPRTMSQEEFDRR
YFKYATDLIPEIKKNGDFFIAGACYPEVHPESKNQEEDIQHLKQKVDLGLNCLITQMFFD
NNAFYSFMDKLEKAGIDIPVHAGIMPVTAAKQLGTSVTLSGSSVPVEMSNMIAKYGENPE
DMKKAGIEYAVNQILDLKKHGVAGVHIYSMNKADVTKQIYEASF
>A0A1A3T1M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. 1274761.0|TrEMBL
MRHGPCGGVRPDGQCEMRPGPCAFPDVVPWSGPEAHGRAAQAPLVLADFSCTPFDAADAV
ATASILAPSADAVLVGEHQNRPDFPPTLMGGLLLEAGVSPWITLSCRDRNRVVLEQELRG
LRSLGVQTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASLGMVAAAPETPTAPPVFA
RPQRLFEKQRAGASLAVLNHVPAPEMIADFMSRARSLGLSIPVIAGVAVFTDIVSASVLQ
GLPGLELDKAVVEHVLDAADPVAAGIAAAVAEARTLLSIDGVAGVNLSGLASGSGTRIGA
EIKAEVGNRIKDEVAA
>A0A4S4FLY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glaciibacter flavus|TrEMBL
MESDTAPRRVPVSFELYPPRSDAAAIALGRSIDRLADADPSFISVTFGAGGSTRDRSLTV
LSYILENTRVEPMAHLTCIGSSAEEANQLVRRFLDAGITSFLALRGDPPTDGSADVGDLR
SAAELVQLIHRVQQEREPFTEQPMPGQPRASRLRARPRPERVAVAAFPSGHPDSRGPQQE
VDALLAKQVAGANLAITQLFYRADDYLDFVERARAGGVTIDILPGIMPATSAARLRRIAE
LTGEKSPDDLLIPLEIEPTDEGRAEIATEFFASLAADVIAAGAPGLHLYTLNKHEAVLAV
IDRLGLRAIPATSQENA
>A0A077MFW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetrasphaera jenkinsii Ben 74|TrEMBL
MSSVNSGPGEPDAWARAPWHDLVRTGRGEVLLYGLTPPRQTTAPEDVARLAQVTLERLAA
IDVDCLVVYDLDDESDRTEVERPFVYSPTIDPSAFLDHLGDWTGPTILYRSVGKYDPAEL
DDWLRAEERDVSTVFVGASSRDKDVRTTLPQAHAAWRRAERETRPGGIPQRAIPLGAVAI
PERHQQRGDEHLRMLAKQESGCAFFITQVVYNVTDAKDLVSDYWYACAERDVRPAPVIFT
LSVCGSKRTLDFLEWLGVDVPRWLANELIHATDPIVESVDACLDTATELATFCRRIGLPF
GFNVESVSTRKVENEATIELARKIRRLLA
>A0A8G0WIL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus inaquosorum|TrEMBL
MGLLEDLQKQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETSLPIMLNVSMHEQGVLQDGTP
LSEALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAIAEAVGGLAPITEKEVKTRAKEFIS
VQHERTEPALNEIAAEKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDSIRETMALAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIYLH
>A0A6J4I8R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Chloroflexi bacterium|TrEMBL
MQRPAALTDPDLLNMPRDLTERERQVLTLRAAGEPVAAIAALLVVEPRTVKFHLRNVYAK
LDLATAPRAARQLALARYAAAAPTVMPVPGRPRPPVRRFLFRPDRTLTQVLAHEQFTFSA
EVIPPRNGAEQAAVLAQVARLIDAGARFLAVTKGAGGSLRGGSLPIALAIKEQFDVPCVA
HFTCRDLLPEEVENQLVDHQYFGIRNILALRGDPPDGQPGWRSRRGAYDHAYQLIEQIRD
LNRGVYLPRAGGPPPATHAPADFCIGAAVYPEHLDAAEGTTFFKRKVDAGAEYAITQMVF
DTDAYGRFLDRCEKARLSVPVLPGTRILRSRARARRTAEKYGVSVPAAMLRALPQIDDPA
ADARALDVFLGVVERLRRLGAPGVHLFVTDVDTACTALAALKQ
>A0A2N2HW31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-2|TrEMBL
MRKNLFKEALLNPSVFPVTWELVPGRGAKESVQEKTLSLAKQAAESGKICALTLTDNPGG
TPAMSADFMGGEIVKLGIEPLVHFTCKDRNRNQIESQLYALDRAGVRNILVMSGDYPVSG
YCGRPAPVFDLDPIHTLRLMSDMNKGLTYPGVKGNIRHQPSDFFPGAVVSPFKATEAEQM
IQYYKLKKKIDAGAQFIVTQLGYDARKIHEVFLFMKQSGFNLPLIGNIYILPYGAAKMMN
RNELPGSVVTDKLLAELERERNDSDKGEGARILRAARMYAIMKGMGFSGVHIGGHNIKYE
QVENIILQGEALTSKWRDLIQYFDYPIPGGFYYYEHDSKSGLNLDKPTTRHSRPLDATVG
LSYGFSRFVHNLMFEPGKKLYGVMKGLSGKVAGTKIESIFHKLEHWTKVVIFDCKDCGDC
ALIDVAYLCPMSQCPKNQRNGACGGSFEGWCEVYPGKKKCVYVRAYARLKKHEEEAQLDK
GIVEPCNWDLYQTSSWINFYLGKDHTSKRQSGNSSGA
>A0A844LYU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sanguinis|TrEMBL
MNKPRFSFEFFPTKTSEGVEKLCQTFDALNELAPSYFSVTYGAGGTTRNRTLGIVETLQN
RANTPIAPHISCIGDDKVQISELLDFYKSIGINRMVALRGDLPSGQVGMGELPFAVDLVR
HIREHSADHFHIEVAAYPEMHPQAKSFDFDIQNLVNKFNAGANSAITQFFYNAESYLYLR
DALEKRGVDTDKHNLVAGIMPIINASSLIRFADSCGADIPRYIRKQLADYGDDRKAIREF
GFEVVHRLCEILISEGVPALHFYSMNRVEPNKRLVESLGLSSVSTQA
>M0M213|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halococcus morrhuae DSM 1307|TrEMBL
MSVTRQSGETDGVAQLLDDPRFELMPFDSFADEMDELPAGATIAITTSPQLGLDATVEWA
ETAAARGFDVSPHIAARYVRDVDHLDEIARRLAEAGVTDIFVPGGDREEPIGEFDSAYAL
LDALDGLDHGFEEIGITGYPEGHEFLDDDTLADAMAKKVPHATYIVTQLCYDPEAVVEWV
KDVRDRGVELPVEVGIPGVMKYDKLLSISRKVGVGDSVKFLKKTTGVVGFVRELVGSRGR
YTPDDLVEGLAPYADDPDYDVQGLHVYTFNRTEDTESWRYGVLDE
>A0A812AHU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MKTALSKGQFVVTAEFYPPKEANGSEIKERALVLKDVVEAVVVRDNPLAQVHTSPIATAT
LLLNVGLAPIVQISIRDKNRFAIQSDILGAVTLGVKAFFAWRTVIKG
>A0A6M4FQF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. PA5|TrEMBL
MSVQEHPLGISFEFFPPNTEAGREKLMGVRDALAKRGPRFFSVTYGAGGSTQARTTQTVK
AVRESGINTAPHLSCIGSDKGELRELLSHYREEGINSLVALRGDLPSGMGGIGELRYANE
LVEFIREESGDHFEIAVAAYPECHPQAPSFERDLENFASKVKAGANIAITQYFFNADAYF
HFVERAQRLGVEVPIIPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIQAF
GKEVISRLSQRLLDGGAPGLHFYTLNQADATLKVLDNLS
>A0A0A2LJL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium beibuense F44-8|TrEMBL
MKVTEHIENANGKTLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYTYKE
LANGLLEKKVVKKRPGTVGICSAIQNKYGVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGNQYASELVSQIVNLNKGIYLDDDLQNTSATDFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGASYIITQMFFDNKKFFDFVNKCRKEGINVPIIPGLK
PLSTKKQLNQVPHRFKVDIPDELIMEVVKAKDNDAVKQIGIEWCIAQSKELVKAGIPVLH
YYSMGKSDNIKAIGKEVF
>A0A4U1AM32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila sp. IMCC35006|TrEMBL
MSFQKRLAAKEFAVLAEMHTPKGINISRLVNDARRLKGRVDAVVVPDMDNGIMRMSALAG
GVLLQQQGVETIMHMYCRDRNRMALQGDALAAHVLGIQNIVVADSTDMNESDHSDATPVN
DLDEVQLIEALMGLQTGKDMSGFDLDGAPDYTIGCTLTPFTDDKGRDAALLTAEKRVKAG
AGYIIVPPIYDVPGSASLLARVNELGVPVIATVFLLKSLAIAQYITNSDPGAGISSDMIR
RIRKSPNRELEGIKIAGETILALKENTQGVLIQTLGWEHKLPEILDVAKI
>A0A5R8LHT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactobacillus casei|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNVALTPILNTLDAVKEADPDFVSVTFGSNGNKPHM
GTLEVAKLIKDEFDLEPVAHLPAAQLTRAQVDAELHGFQEAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQRGDFNVVAACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYRFRERTELAGIHVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIATATKTIRNA
>A0A2M8DXE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium CG_4_9_14_0_8_um_filter_55_61|TrEMBL
TALCEKLIAGGAPGLHFYTLNQAAPCLAIIERLGLSK
>A0A4R8PTL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum spinosum|TrEMBL
MDKITDKIAALPADANYFSLEFFPPKTQMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
STKSLELAEICQRELGLTTCLHLTCTNMSRTLIDKALEDAKALGIRNILALRGDPPRKDE
YRTADDSDVEDMDDFVWAIDLVRYIRKKYGDYFCIGVAAYPEGHADESHPLGQSFEHDLP
YLVDKVQAGADFIMTQLFFDIKAYDNFERVLREHPSGAFKTIPLLPGLMPIQSYQMIKRT
TKLSHAKVPADLMARLDAAKGDDERVKRVGVDILSELVQQVKEVKSRTPGPKGFHFYTLN
LEKAVSFILERTGLIPDADEDEEAVIDDAIGVPTVQLNGLSPIPPSTPRTFSGRRQSSIG
SDPHNRVIVSSASNPAYETTAASLSAEPVNTRANTLAISEGEGVLGREATWDDFPNGRWG
DARSPAYGEIDGYGVSLHMSVTQAVGLWGTPKTVQDVNNLFIRHIKGQLSAIPWSEEELL
PESNIIQQELLGLNTRGWWTVASQPAVNGIPSRDPTFGWGPQHGFVFQKAFVEFFLPSAD
WASLVARLNEVTDNTICFYAANAAGDFVSSDASGGLVLEGTECSTNAVTWGVFPGKEIIT
PTIIEEVSFRAWADEAFKIWGEWAKVYGKGSESEALLERIQSDYWLVNVIHHDYVERDAL
WQLLNGEKEI
>A0A2N5DVQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chimaeribacter coloradensis|TrEMBL
MSFFHANQRDALNQSLAELHGQFHVSFEFFPPRTSEMENTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRRIAQDYWHSGIRHIVALRGD
LPPNSGKPEMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVSAGIDVEIVPGILPVSNFRQLQRFAALTNVRVPQWMTSMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGIRPGVVAPA
HA
>A0A4Q9URF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azotobacter chroococcum subsp. isscasi|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLTVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRNLLNTYRDAGIRRIVALRGDLPSGMGMASGELRHASDL
VEFIRAETGGHFHIEVAAYPEMHPQARNFEDDLRHFAAKMQAGANSAITQYFFNADSYFH
FVERARKLGVEQPIVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFG
EQVVTQMCEKLLDGGAPGLHFYTLNQAEPSLAIWNNLGLPR
>A0A2K8Y6K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. SK17|TrEMBL
MTETVSPVPNGHRTPNVPKISFEFFPPKTEEMERTLWDTINRLAPLTPNFVSVTYGAGGS
TRERTHATIARILRETDLLPAAHLTCVSSSRSEIDEIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAGIKKRHADIEISVSAYPEKHPEAADFDADIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDKVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPGWLAE
KFDGLDHDAETRKLVAATVAAGQVQKLFKRGVDTFHFYTMNRADLVFAVSHLLGIRPNGA
QKAA
>A0A1Y4F7L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. An269|TrEMBL
MKVINLIKSSEKTAFSFEILPPLKGTGIEKVYETIDLLREFDPKYINITTHRSEYVYTEL
GNGLFERKRVRRRPGTVAVAAAIQNKYGIPVVPHVLCSGFTREDIEYMLLDLQFLGITDL
LVLRGDKAKHQSVFTPEPGGYSHAIELENQINDFNRGIFIDGSPIKEPVHPFGYGVACYP
EKHEEAPNMEQDIYWLKQKIESGAQYAVTQLFYDNAKYFAFVDRLRAEGINVPIIPGIKP
FGKLSQLSVIPKTFKVDLPQTLVAEAMKCHTDAEAAELGVEWCINQCRELMRHGVPSIHF
YTVGAAQSVSRVAKAIY
>A0A0Q8RTA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. Root214|TrEMBL
MTSNLNSLAEARRAAASPLFANLEGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASRAEIDEVAQAYWDAGVRHIVA
LRGDVPGGAPYRAHPDGYANAIELVAGLKAIAPFDISVAAYPEVHPDADCAESDLDNLKR
KLDAGATRAITQFFFSPDSFLRFRDAAAAAGITAPIIPGILPVSNVSQTRRMADMCGTAI
PGWMISLFEGLDDLPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPAAAPATEKAA
>A0A2S0REH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium magnum|TrEMBL
MKVTQHIDNAQGKTLFSFEILPPLKGQNIRSIFDSIDPLMEFNPPFIDVTYHREEFEFRE
LDNGLLEKKIVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTREDTENFLIDIDFLGIQN
VVALRGDAIKSEIYFRPEKEGHHYASELVTQIDNLNKGIYLDPELQNSARTDFCIGVAGY
PEKHMEAPSPDSDIYFLKQKIKNGAQYIITQMFFDNKKYFDFVAKCRVEGITVPIIPGLK
PIATKKQLNMIPHRFKVDLPDELIMSVVKAKDNDTVRQIGIEWCIEQSKELVSAGIPVLH
YYSMGKAENIRAIAKEVF
>A0A497YG48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planococcus citreus|TrEMBL
MLLDELKKRMLTADGAMGTLLYSYGIEYCNEELNIQRPEVIEKIHRDYIAAGADIIQTNT
YGANAHKLARYGLEEQTEAINKAAIAIANKAAKDGGQFVVGTIGGIRGIRKSDATLDEIV
AMVDQQAQHLLSGDPDGLLLETYYDFEELAATVSHLKKLTDAPLIAQLSMHEPGILQNGM
SLNEGLKRLDALGAEIVGVNCRLGPHHTIQAFEGVELPEKAFLSAYPNASLLDIEDGRIV
YESEADYFGRAALLLREEGVRLIGGCCGTTPKHIEAVKKRIGHLQPITEKKVEEKKPIVI
REAEALKDKPLHEKAKTERTIIVELDTPRHLDIEKFLEGSKALDAEGIDAITMADNSLAS
PRISNMAMGSILKHKQDVRPLAHITCRDRNLIGLQSHIMGLDALGIHDILAVTGDPTKVG
DFPGATSVYDVSSMELIQLIKKLNEGISFSGKPLRKKANFSVAAAFNPNVRVVERAVQRL
EKKIEAGADYFISQPVYTKEKIIEIHEATKHLDTPIFLGVMPLTSIRSADFLHNEVPGIK
LSEEALDRMRACGEDKDKATAEGIQIAKELIDTAAELFNGIYLITPFVRYDMTVELIRHI
RQLDLKKASDRAYA
>A0A6I7DE70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus columbae|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPQTEEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASREELQHIAQDYWQSGIRHIVALRGD
LPDNTQKPDMYATDLVHLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMFD
GLDNDPETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPELIKA
>A0A2D0QYL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ictalurus punctatus|TrEMBL
MVNQREENGLLWIKSDSSGASNSGESSKNSSKESSRCSTPVGESDRGNRLRDKMRRRIES
GDCWFSLEFFPPRTAGGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIAST
AVNYCGLESVLHLTCCKQTKDKLTFYLNKAKHLGLKNIMALRGDPVGADWEEEEGGFNYA
VDLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRRLKEKVDAGAHFVVTQLFFRAET
FLKFLKDCRAIGITCPILPGIFPLQGYHSLRQLVKLSKLEVPEEIMKVIEPIKDNDAAIR
NYGVQQAVEMCKVLLNSGDVPGLHFYTLNREVATTEVLRQLGLWAEDPRRPLPWTVSAHP
KRKMEDVRPIFWSTRSKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKE
ALLKMWGEELTSEQSVYEVFTNYITAQPNQNGHKVMCLPWNDDPLAPETNMLKDELEKVN
RRGILTINSQPNINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSNENAKALLKVLKKYEPR
VNYHIVNMRGENITNAPELQPNAVTWGIFPGREIVQPTVVDPVSFMSWKDEAFALWIEQW
GKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLNSCLWQVIDDMFELLSAPPEPLEENIH
SQTDAVSF
>A0A7W6DV13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sagittula marina|TrEMBL
MTKPEISLEFFPPKNIEGTFRLWDSVQVLAPLAPRFVSVTYGAGGTTRDLTRDVVATIHK
HSGLRTAAHLTCVDATRDETLQVARDFAKVGVTDIVALRGDPPKGSAGFTPHPEGFNNSV
ELIEALSDTGDFTIRVGAYPDIHPEAASAQADIDWLKRKLDAGATEALTQFFFESETFFR
YRDACAKAGIDQYITPGILPIENWKGARRFAEGCGTKIPQWVIEAFETAERDGRTDLLAT
AICTELCDELLQGGVDKLHFYTLNRPELTRDVCFALGVTPEAKLQNVA
>A0A285UTB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ureibacillus acetophenoni|TrEMBL
MGLREALKSRVLTADGAMGTLLYSYGLDYCHEEMNLVKPELIEKIHSEYIAAGADIIQTN
TYGANAIKLARYGLESKVVEINEAAIRIAKNAVNNGDQFVLGSIGAIRGVRKSDTTLEEI
LDAIRVQAEVLIKGELDGLLLETYYDFEELTETLKLLRTMTDLPIIAQVSMQDPGVLSNG
LSLNEAFSELEKLGADLVGVNCKLGPYHTIQAFETVDLPKRAFLTAYPNASLLDIEEGRV
IYESEVDYFARAAIELTNQGVRLIGGCCGTTPKHIEAVKKQLANRKPIEQKLAKPAKEVL
IRDPEPRNTEPLHEKVKRERSVIVELDTPRHLEVDAFVEGAKALYNNGADLIMMADNSLA
SPRVSNLAMGAILKQHGIRTMPHITCRDRNLIGLQSHLMGLNALGLHDILAVTGDPTKVG
DFPGATSVYDVSSMELISLIKQLNEGISFSGKALRKKANFSVAAAFNPNVRVLDRAVSRL
EKKIEHGADYFISQPVYTKEKIVDIYEATKHLEVPIYIGIMPLTSFRSAEFLHHEVPGIK
LSDEALERMKSCDGDKVREAEEGLAIAKELLDTATKYFNGIYLITPFLRYEMTSQLMDYI
KQLDEEVKGVYVNG
>A0A7K6T2S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caloenas nicobarica|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDTDRHERLREKMRRRLDSGDR
WFSLEFFPPRTANAAVNLISRFDRMAAGGPLFIDVTWHPAGDPASDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITVNLQKAKRLGLKNIMALRGDPIGEEWEEEADGFNYAVDL
VKHIRNEFDDYFDVCVAGYPKGHPEAESYEADLRRLKEKVLAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A4Z1B0R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Empedobacter tilapiae|TrEMBL
MKVTEHIERANGKPLFSVEILPPLKGQDVNATFKTLDPLVELNPAFIDVTYHRQEYIYKQ
KENGLLKRYQVRKRPGTVAICAAIQNHYKIDAIPHLICGGFTKEDTEDALIDLNFLGIDN
LLVLRGDPIKSEKSFVPEIGGHAHASDLIEQITALNTGNYLDDELQESHAMDFCIGIAGY
PEKHFESPNLGMDLYYLKKKVELGADYIVTQMFFDNQKYFDFVKKCREMDINIPIIPGIK
PLTSFNHLTSIPQNFYIDLPECLSMEVLKANDKETIKQIGLEWCINQCKELVEFGVPGLH
FYTMSNSNNTKTVAEAIF
>T0HYM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. HDIP04|TrEMBL
MTAKDVASLADAAPMIPAGTPISVTYLPGETMPARVAAARTVKSLGFVPVPHISARRLPS
KDDLVEFLTVLDGEVGIDRAFVIAGDPPAPMGPYEDALAVIRSGLLDRAGIGTVGISGYP
EGHPDIGREKLDQAMKDKIAALAEQGKRVEIMTQFAFDADAILDWLARIRRDGVAAPVRI
GLPGPASVGKLIRFAARCGVGASARVMVKYGASISRLLSTAGPEHLIESLARQRDPAIHG
EAMLHFYPFGALVDTARFIRSHYGDARE
>A0A1U7MU01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ornithinimicrobium sp. CNJ-824|TrEMBL
MTATQSRISVELVPRSEESIRTEMAAVAEHLPWADTVNVPDLVKFDLRSWEATALARECA
RRADGTAYRAIPHLRAADVDPEAPLRMARSLADQGAEEVLVVSGDDADYFTHHTYPVDAV
DVIRRIRAELPHLTVYAGLDPYRQGIAQEMRYLERKLSAGAAGVFTQPFFDVGLMGAWAR
ILPQDLPVWWGATTVTSNGAIGYWRRRNLVAFPTDFEPTLQWQRTFARRAIDFARERGHH
VYLMPVRTSVTDYLAGVV
>A0A094AK06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4513|TrEMBL
MHIKDMLNQGEQAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHA
QLTCEMVSVAQSVYGLETCMHLTCTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEK
WVATDEGFQYARDLVRYIRKTYGDHFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATF
IVTQMFYDVPNFLDWVRKVRAKGINIPIIPGIMPISTYASFLRRCNHMNARIPPGWIEAM
EPVKNDDAAVREIGRGLVTDMCRAILESGINHLHFYTMNLAQATRGVLEQLEMLPSEARP
LKQALPWRQSLGLGRRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGEPKSVKDIANVFLRYLNADIESLPWSEAPISNEADVIKQQLVK
LNERGLLTINSQPAVDGVKSSHPVYGWGPLNGYVYQKAYLELLVAPELIDELLDRIAKDP
EVTYYAVTKSGTLRSNAPGDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHDASTPSRNVIQRVMETFYLVNIVHNDFHQRDALFSLFEGLAVPNIDQPAEGSVAPA
AAPAASAANGDKVEDAPPAIVSNVLPVA
>A0A482KFZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Homo sapiens|TrEMBL
GNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEVLTSEESVFEVFVLYLSGEPNRNGHK
>A0A1H9MGA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosomonas sp. Nm51|TrEMBL
MESQKKFFPTYSFELFPPQSEQGIEKLKEARKKLAQLNPKFFSVTFGAGGSTRERTLETV
LEMQSEGYRVAPHISCIGSTRQNICSILETYHAAGVDQLVALRGDIPSGMAQAGEFRYAS
ELVAYIREAFGQVFHIEVAAYPESHPQARSMQADLENFKRKIEAGADSAITQYFYNADAY
FYFIESCESMGLSVPIVPGIMPINKFSQLVRFSDACGAEIPRWIRKKLEWYGDDTASIHA
FGLDVVTDMCERLLKEGAPGLHFYTMNSANLTSEIWRRLGLETMH
>A0A7V1VRA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
AMGMTFLDRLNREVLLADGAMGTLLLARGIEPKALMEQNLTHPDLIRQVHLDYIRAGAQL
IETNTFLANRLRLAEYGLDSELEAINRAAVRIAREAVRMSGEEVFIAGSVGPLGALVKPY
GNLTLDDLSAAYVEQIAILVDEGVDVIIIETHPSLLEALEAVRAAKTVSPTTPIIAQMTF
LEDGKSKFGDDLRRSLEALAAADADVVGVNCSGPQMTYDIIYEFLTTTDLPVSIMPNAGL
PQFIGGRTIYLSSPEYLREYARRFVEAGANLLGGCCGTTPEHIRAMSTVVRGQVPRRVRQ
RTAVFVEVKEEPTAAPSTVPLRGRFRERLGREFVVTVEVHPPWGLEYRSPIERIRQLAHC
GVDAVSVHDPPEARVSLSSLVFAYLVQTQAGVEAIWHLSCRDRTLATIHSELLGAAALGV
RNILALTGEAASVGEWPRRPSAHDVSPTGVVKIIEGLNRGRTLTGNDIGSPTDFRVGVLV
QVGAEDLDAELRKLEERVAAGAHFIVTTPVFDVERFEHFLK
>A0A5P8YM22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pestis|TrEMBL
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIAIDYWNSGIRHIVALRGD
LPPNSGKPEMYACDLVGLLKDVGDFDISVAAYPEIHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFD
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A7S1ALW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Noctiluca scintillans|TrEMBL
MATEQHRKDSMLNELMSARKDTWYSFEYFPPRTEEGVKNLYKRILRMKTLDPLFLDFTWG
AGGSTSDLTMQLCDKVKNEFGAVANMHLTCTNMEKDKVDVALADCKKFGICNLVALRGDP
PRGEDKWEATEGGFTCALDLVKYVRANHGDYFSIAVAGYPEGHPDAIEEVEGGLAALTES
EKRRARVAKNEAGVEVVTVCREANFHKEMTYLKEKIDAGSQ
>A0A7C2CIE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MGTAFLDRLNREVLLADGAMGTLLLARGIEPKALMEQNLTNPGLIRQIHLDYIRAGAQVI
ETNTFLANRLRLAEHGLESELEAINRAAVRIAREAVRMSGEEVFIAGSVGPLGALVKPYG
NLTLADLSAAYTEQIAILVDEGVDVIIIETHPSLLETLEAVRAAKTVSPTTPIIAQMTFL
EDGKSKFGDDLRRSLEALAAADADVVGVNCSGPQMTYDIIYEFLTTTDLPVSIMPNAGLP
QFISGRTIYLSSPEYLREYARRFVEAGANILGGCCGTTPEHIRAMSAVVRGQIPRRARQR
VVVSVHAAEESAAAPAAVPLPTRFRERLGREFVVTVEVHPPRGMDYRAPIERIRQLARCG
VDAVSVHDSSQARVSLSGLVFAHLIQAQAGVEAIWHFSCRDRTLAAIYSELLGAAALGVR
NVLALTGEAASAGELPRWPSAQDVSPTGVVKIIEGLNRGRTLTGNDIGSPTDFRVGVLAQ
VGAEDLEAECRKLQERVEAGAHFIVTTPVFDLERFELFLKRCVAFGVPILVGILPLKSAR
HAEFLHHEVPGITIPDALRERLRRAREDEAAEGMRIAHELIVALRPHVAGVHVIPPSERW
DALPDLLAACFPREPAAGGRNA
>A0A6N9A0T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTGLGAGNTRGNRRSAGARPGLAARLAQPGPMAAVELRPPRRGLDTARSMDFWIDMYHAV
QRFARQGTFVLLTDDAAGDAEEESLAHLAANLGDGSDFGTVVPFLTCKHPLEYCRMFARR
AAALGTAGVAVVGGDHSVGPERCVPHGKDLRAVLREDQPGFPLGGWANPHRDPVKQARFV
AADDFGADFVLTQIVSHHSLGRVARFRAELDRLGVDLPVVYGVFLYRSANPRTLRYLDRY
FPVPAREVTAEFAAGLSADEICARSVRRLGEAGAEKVYVSNLRSRDAARRLGEVVGG
>A0A2E4HZA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MNSPKDTLRSLMADGNVHVMDGAMGTEIYARGVFVNLSYDGLNLENPSLVHAIHKDYVNA
GAEIIETNTFGANPAKLSAYGLAEKTELINKTAAQIAGKAAGNNAHVLGAIGPLGVRIEP
FGPTAXXEAQELFTRQIVGLMEGGVNGFILETFSDLNELEQAFLAVRAKSDLPIFCQVTV
GEDGSTVYGTSPEAVATEMSDWGADVVGVNCSVGPAVMLDVIERMVKVTDRPISAQPNAG
LPRMVGDRKMYLTSPTYIGQYARNMTDAGARFLGGCCGTGPDHIHRIKESLEKMPPLSGI
QLERVSITENESAFELATPLAEMSQLGGKISEGTFITSIEISPPKGPDPSEMIDQCKLIE
AAGADSINILDSPYAPGRMSSLPAGIIVEKEVEIETVVHYPCRDRKMSRMISDLLGASAS
GISNLLLVTGRPPPAGPYQPALSGIDIDSIGLTNVVTGLNKGIDPGGNKLTHRTNFVIGV
RMNHLAMDQEKEISRLNWKVDAGVHFLTTHPIFSTERLKQFLEGIPDFKIPVIGTLWPLR
SFREADYLHNEVPGIQIPKTIFDRMERAERKGDIEAKAEGSRIARELFDTMQPLVAGLQI
KASEQNFGEALNLLNKVKNI
>A0A6B1I1P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MDNPTVPMHPFLAALHHRALLADGALGSYLFALTGRVSEQNHLYEAFNLTRPALVRQLHL
EYLQAGAQCLTSNSFAANATYPSAASIAELNAAAVRLAREAIDQYCQQAQYSDPLFVLGS
LGPPLPAAQAPRTASDLYRAQIEALVESGVDALLLETFTCLDQVAALLELLQDLDNPVPV
IVQMALHQRDGTWEQAPQAYIQTAAALGADVVGINCCALPEARAFFVAVQGCASVRDGQV
QLAVMPNGGEFRRVGHRYLTGVNPECMGRFAREMANKGVRLIGGCCEVHPPHIHEMHNYL
HGLAAGKRIVQLARTPDQQPTDATAKRRNGPFSRKLIDGQFAVSVELLPPRGTGGLKARL
AFVAELAASGLADALDITDGSRGIPLMPPGDFIHLIRRRLHWERDRLELIPHCTCRDLNV
MGLQSRLIGYWANRIHNVLFITGDPPKMAPTYPRSTAVFDLDSTTLIRYAHAFLNAGLDF
GGQPLGTHRDPRTHFTIGTGCEPEALDLQREWERLAHKIDAGADYVMTQPTFDGKALAAL
TTYRAQVPIIVGVMVLRGLEHARRIAEVPGVVVPEAIFAELDAYADPADQAKAGVELAAE
QVRQVRAEGWSGLYLMSPAGHQSVLEVLKRGLD
>W4PZE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus wakoensis JCM 9140|TrEMBL
MSFLEKLASKVLIGDGAMGTLLYERGVDQCFEEVNLTNSEKIHRAHAEYVSAGADVIQTN
TYAANRLKLEKYNLEKEVHSINRAGVQIAKKAAEDQSFVLGTIGGIRRFQLEEWDLQEIE
SAFLEQMNELLTEGVDGLLLETFYDLEEAKMATALARKLTAQPIVVNLSLGEIGVMNGGI
AVSNAFEQLTDIGADVVGLNCRTGPFHMLRSFETIALPERAFLSAYPNASLPDYRDGRVF
YQSNADYFQDMGEKFIKQGVRLLGGCCGTTPDHIRAFAKMRDVTQPITTKKVKTILGVER
NPISIPRKEIPLPDIVKERKSVIVELDPPKKLNTKRFMEGAKALHEAGVDAITMADNSLA
SPRVDNLALGSMMKHSIGARPLVHVTCRDRNLIGLQSHLMGLDALGIDDVLAVTGDPTKI
GDFPGATSVYDVSSFQLISFLKQLNEGISFSGKELGQKANFSIGAAFNPNVRHLDKAVKR
MEKKVESGADYFMTQPIYSIEQIEALANETKHIKEPIYIGIMPLTGTRNAEFLHNEVPGI
KLTDDIRSAMAACGEDKEAATLEGIKIAKHLIDATLNFFNGIYLITPFMRYEMTVELTKY
IESRKPIIQTSK
>A0A7C3FWM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineae bacterium|TrEMBL
MQFKAIYRTAQHPILSIELFPPKTEKGRAHLEKELAQLMQHQVGFVSVTYGAGGSTQNNT
LDLVKRIRAQYGVTTVPHFTCVGASRQSILAYANRAIAEGAENMVALRGDPPRGQTTFVP
APDGFRYAYQLVVFLKERFGDRLSLAVAGYPEGHVETRDLATSIEHLKIKVDAGADLVIT
QLFYDNADFFRFRDMAVKAGINVPIVPGLLPITKYSQIDRITKLCGASIPADLTKLLLSF
EDGSPDQQMAGIAAAIDQAGELLENDVPGIHIFTLNNSFATAHMVEALGHYFE
>A0A7X3WB21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MNTSLLDHLRSSLLVADGAIGTMLYARGVPMEVCFDEINQSRPDLIRKIHEEYVDAGAGL
IETNTFGANALSLSKYNLEDQAEALNARGIEIARQAVGTRAYVAGAVGPARGLPHREYTE
DDHRRVYTEQIAALAGGGADAIILETFLRLDDLKAALAVCREVCGLPVICQLAVDQYGQS
DDGFEVVEAFDQLGAAGADVVGVNCRSGPKGLLDALAPVPLTEGLVLSAFPNAGSPVYVD
GRFIYEATPEYFATSALRLRDQGVRLIGGCCGTMPEHVQAMAQALEGQEIVTRKKVLPVE
VRVPARPAGPARPARPAPAPPAVEPSIVDLVKERVTVIVELDPPRDLDHGPIVRGAEALK
KAGADALTMADNSLAVTRISNMAVGQIVKEEAGIRPLLHITCRDRNLASLQSQVLGLHAL
GIDHVLAVTGDPVKFGDQPGASNVYDISSFELIRLIKQMNEGVGFSGRTLNGRTAFTVAA
AFDPNGPNLERRIRRLERKVEAGADMIMTQPLFDRRQAKQLYEATRDAGVPILPGVMPLV
SDGNTEFLHNEVPGFVVPDDVRARMARVGRGRKARREGVAIARELIESVLTYFNGLYLIT
PFNRYPMTVELTEFALQATARKAPE
>A0A7Y3IAP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MTDFRALLEDGRVHVLDGAMGTMLYARGVFVNVCYDELNLSHPRLVADVHEQYIRAGAEV
IGTNTFGANPVKLASYGLEERAAEINERAAAIARDTGAGRAVVLGAIGPLGVRVEPLGPT
SLEEARDFFRVQAEGLASGGVHGFALETFSDLSEMEQAFLAIRQVSDLPVLAQVTVGDDG
LTSYGTSAEQAGARAESWGVDAVGLNCSVGPAVILEALERMAEATNLPLVAQPNAGLPRV
VGDRKMYLAGPEYMAQYARRLIQAGARFVGGCCGTTPEHVRQIRESVIALQPRTPAVRVT
RTVGSKEIRQEPVPLENRSRLGRKLKTGEWVTSVQIRPPRGWDAAGLVADCRRLATSGVD
AVTLYEDRGASRLGVMAAARLVLQSCAIEPLVHYTCQSRTLLDMISDLLGAAAGDVRNLL
VLSGDPPAGAPYREYASVIDVDSIGLINVISGLNAGIDPSGNEIGRPTEFVVGVAVNQGA
RDPAREAGRLYWKADAGAHYVVTQPVFDAEHLFGFLDGVEGVDLPILAGIWPLTSARQAE
YLQNEVPGVYVPPSVTERMRTAESQGPESAAAEGLALAREVASEVRARVQGLHVVAPDGR
LDPALAVLRSSR
>A0A3T0M3I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Brevibacterium] frigoritolerans|TrEMBL
MNFRKELKERMLVGEGAMGTLLYSNGIDQCYEELNCTNPDQIESIHRAYLEAGADILQSN
TYGANFNKLKRHGLEDEVSRINRQGVILAKKAAKGKAYVFGTIGAQRSIRKSDLSMEEIK
RGFREQLYSLLMENPDGILLETFYDLEELETVLQIVKNETGLPIIANVSMHELGNLQNGI
HLNEAFLKLEQLGADVVGVNCRLGPHHMIRALEEVSLPKQASIAIYPNASLPDYVDGRLV
YKAVPEYFGSSALELREQGAAIIGGCCGTTPLHIQAVKHAIGSLAPVKEKFTKSREIEVI
EVNDRELELPLYEKAKTERTILVELDPPKKLGIESFMTGAEVLKKAGVDSITLADNSLAS
PRISNDALANLLKNQLNINPMVHITCRDRNLIGLQSYLMGLQTVGLNEILIITGDPSKIG
DFPGATSVYDLSSFDLISMVKQFNEGLSYSGQSLGQRANFKIAAAFNPNVKYLDKAVLRM
EKKIACGAQSFLTQPIYSVEQIEEVYEATKHLETPIFIGIMPLTSTRNAEFIHNEIPGIK
LPDNVRRAMALAGDDPVKSRIEGVNIARELVDAAREKFKGIYLITPFLRYEMTAELTKYI
RKVDSKQTSEVAVHE
>C6E1U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacter sp. (strain M21)|TrEMBL
MRIVEKMNQARQFVSLEFFPPKDRNEWPAFFKTVDRLSQINPLFASVTYGAGGSTKGDTL
EIVKRLQGESGLDTMAHLTCVGAYRGDLQLFLDELALAGVKNVLALRGDLPNDTPPEFSA
CRTLLHASDLAAFIRESHPEMGIGVAGYPETHPEATDPERDLGYLKLKLDQGGDFVITQL
FFDNQLYFDFVAKARAAGIDKPIIPGIIPVVSLKVIQRIISMCGATLPPAYLAELEDADR
SGGSAAVQKAGIAYARRQAQELLAAGVPGVHIYTLNRDQAVLELVDGLLPS
>A0A3M2BUG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
PGGSPIGEPTRFVIGVVANQGAVDEGRELERFMWKVDAGAEFVVTQPVFDPARLRAFLER
TAEWPVPVIAGLWPLTSLRNAEFLANEVPGVHVPERVLRRMELAQAESREAAEAEGVRIA
LEAYREVADIVAGVHITAPGGDVSRALAVLEGVDALG
>A0A2E4MZN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MRFRDFFKGNTRPVISFEIYPPKTKRGLHALKSRLLPKLIELGPSYITVTYGAGGSTQGE
TLEIASTVKNELGLEAACHLTCVGASKSEIDDIIGRIRTEGINNIVALRGDPPTGQDQFV
AHEEGFNHANELVEHIRATEDSNSRAGLAVAGYPEKHLEAESLDVDIENLKRKVDADADI
VITQLFYDNNVFYDYRDKVAAAGIDIPIIPGLMPIQSRSQVQRIASLCGATLPKNLLGQI
EDAGDDDEAVKVIGTEQCTAQSQGLIRNGAPGIHYYVLNR
>A0A1F3V7E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionales bacterium RIFOXYC1_FULL_37_79|TrEMBL
MQIKDYFFKKKLTTSFEFFPPRSQKASDNLFETIKKLVPLKPTYVSVTYGAGGTTRELTN
DLVIKLHKETKLTIVPHLTCVGSTRKDMEKIITNYQDNGIQNIMVLRGDIPKNESIDLSK
NDFKHAVDLVRFIKKIHPQMGIGVAGFPEGHPECTNRLLEIDYLKEKVDAGVDYICTQLF
FDNKDYFDYIDRCQLAGINIPIIPGVMPITSLSNLKRMADLAQGVRFPAKLLKSVIRTSN
DSQVFDVGIHWAAEQASGLLDNNVPGIHFYTLNKYESIIQICKSLGISTLDELTKEKLLS
DKF
>A0A3D5ULF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacteriaceae bacterium|TrEMBL
MKITELFQRGEFVTTAEVGPPKGWQIDHLLDEVNTYLKNRVTAVNVTDNQSSVMRLGSLA
TCKSIIDQGALPIFQLTCRDRNRIALQSDILSAALLGIENLLLLTGDYTTLGDNPQSKPV
FDLDSVSLLHMVKKLEQGEDLAGNPLDGDPPSFAKGAVVSACSDSVDVQLAKMERKVEAG
AEYFQTQGVFEPEKFIRFMEKAKQFNVPVQVGIIIPKSVGMVRYMNANVAGVHVPEDMIE
ELKKDKEKTKAGITGVEIASRIIRECKDYCQGVHIMALGWESKVPDILDQAGV
>A0A1I1BT03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. 344|TrEMBL
MPWRSEAVTGALTHRDTPRPAGNITHGYSLEVSAKDIAALSAAAPRILPASTIAIPYLPR
EDNAARLAAARAVRSLGFEPMPHFSARRIASLAELASFVQRAVAEADVARCFVIAGDPAT
PMGPFSDSAALIDTGVFERAGMRVIGVAGHPEGHPVMSTAEQWEVLERKCHSIIERGMTP
IIVTQFAFDADIVLTWLHALRARGIAHPVRVGVPGPASIAVLARYAAVCGVGACASMWSK
YGISIGKLFGSAGPDLFVERLAAGLTAAHGKVSLHFFPFGGIAQSVKWIEQYRSRAEPAP
>A0A255PEW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. FBKL.4005|TrEMBL
MNPALQDDLLDDFSLEMTGKDVPGLEAARDSIPPGTRINITFLAGEDTATRLTAARAVKR
LGFVPVPHISARRLPSRPALEEFLAGLAADGTAENVFVVGGDPARPEGPYEDALAVLRTG
LLRQHGVRHVGITGYPEGHPGIAERTLWSALTDKAAAIGAERFGGDVITQFGFDVDPVLA
WLEALRARGVHLPVRIGVPGPAGVRRLLGYATRFGVGTSASVARKYGFSLTNLMGTTGPD
RFLRTLAERYDPARHGTVKVHFYTFGGLRATAEWITGFRHAATAGTRA
>A0A0M8R792|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces rimosus subsp. rimosus|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVQHPEGVLYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATQLCARLMAEGSPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A2T8HQ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararhodobacter oceanensis|TrEMBL
MSFSASDPTKPYAAPPEGFSSGSELERVLRAGKFAVTSELNPPDSVDPADVFEAAAPLAE
VTDAINATDASGANCHMSSIGICAVLTRARIETVYQISCRDRNRIAMQGDVLGAAAMGVR
NVLCLTGDGVGAGDQPGAKPVFDFDAISLIRTIRTMRDSGQFLSGRKITKPPHLFIGAAE
NPCVEPLDWRAQRLQKKVEAGAQFIQTNYVFDLPRFERFMTRVRDLGLDENVYILAGIGP
LASAKAARWMRNNVPGIHIPDDIIARLEGADNQGDEGRKICVEFLQKFREIKGVSGVHIM
AYRREHLVAEILREAGLTER
>V9VRX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leisingera methylohalidivorans DSM 14336|TrEMBL
MQVLAPMDPRFVSVTYGAGGTTRTLTRDAVAALHKSSGLNVAAHLTCVNASKAETLEIAD
QFAEAGVTEIVALRGDPPKGEGKFTPHPDGFASSVELIKGLALRGNFNIKVGAYPDRHPE
AADQAADVEWLKRKLDAGADEALTQFFFEAETFFRFRDACEKAGIDGSKLTPGILPIENW
KGARNFAKRCGTIIPQWVEDAFDKALRDDRAELLATVLCTELCSDLLEGGVDKLHFYTLN
RPELTRDVCFALGVTPKVSLQNVA
>A0A522PKE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MATILEDLRSGILLADGAMGTMLIAGGAAPHLCLEARNLEQPQAVRTIHDRYVEAGADLI
ETNTFGANALKLADFSLEHRLAEINAAGVRLARHAARSASRRVYVGASVGPLGKALHPYG
TMTEERAVEVYREQCAALAAERPDAFVLETLTGLAEARAAVRAALEAAPNIPRICTLAVL
EGGQTQYGEDVGEVLRALIDAGAEAVGLNCALGPAQTYEILAPIAGDFSVPLVASPNAGF
PGRLHGRTVYFSSPEYFAEYAGAFAELGINLIGGCCGTTPAHTAAMRQALRGASPGDRRA
VHVVSVHDYERPAAPPPLRRGNAFEERLGREFVITAEIEPPRGIDYRAQLAGARMLEEAG
ADAVNLTDNQRAQLRMSPIALASLLMQHTSLATILHFSCRDRNLLALQSELLGAAALGIT
AILALTGDPATFGDYPVATGVYDVTSVGLVGILRALNDGKRHGGIEIGPPASFKIGVAVN
PLARDIDAELARFRRKVAGGAHFALTQPIYEIAALRRFVSELERAEIAPIPILAGVLPLR
SSRSADFLHNEVPGMFVPEAIRERMRRAGENSAREGVRIAREFVEEARTLVGGAYVIPMG
RYEAAAEVIVPIAAAR
>A0A7C2S8V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MNAAPQISCEFFPPKTDEGAERLRTTWQALKAIDPAYFSVTYGAGGSTQERSFATVSEIQ
RDSCVPAAPHLSCIGSTREHIRAILNDYKAQGIRRIVALRGDLPSGMRDPGELRYANELV
EFIRAETDDWFHIEVAAYPEFHPQAASATADMEAFQRKVEAGADGAITQYFYNVDSYLRF
MNDCLDRGIHIPIVPGIMPITNHTQLARFSDACGAEIPRWLRKRLEAFGDDMDGLRSFGL
DVVGELCQQLIEAGAPGLHFYSMNQIEPTLSLWRGLSQHLRADIEL
>A0A7R7ZNW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus chevalieri|TrEMBL
MHVKEKLAQNEANGKTGISFEFFPPKTAQGVQNLYDRMDRMHSLGPEFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAALHAAYKAGCTNILALRGDPPRDKEQ
WEVVDGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKIDAGSSF
VITQMFYDTDNFINWVKKCRAKGITVPILPGIMPIQTYAAFLRRANWTKARIPQDWLDAL
EPVKNDDAAVRDIGKTLIANMCRRLLDSGLIKHLHFYTMNLQQATQLVLEELKLLPSEET
PLPKPLPWRPSLGLKRRAEDVRPIFWRNRNSSYIARTQTWDEYPNGRWTDSRSPAFGELD
AYGVGLKGTNEQNIKLWGEPKSVQDITTIFIRYLKGELSRLPWSDTAISGEADAIMENLI
NLNSRGFLTINSQPAVNGAKSSHPVHGWGPKNGYVYQKAYLELLVPNDVVDELVSRIEKN
ADLTYHAVSKTGSLRTNTLDSPNALTWGIFAGREVIQPTIVETVSFLAWKDEAYRLGEDW
AKCHDAASPSRKLIQSVVDNWSLVNIVNNDFHNTYDIYRLFDGLNVKDLDVEVSGDVLVP
QQNGASAEAAAAN
>A0A4V2LLJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4910|TrEMBL
MPLLTDSLQNQPFSIFLEYLPTKHTQPVPSCIGGYPVTMTIADRVRTDDDPEPLVIAQNY
AAEIPKILHFSGKGRDIADFNEFIRAAQVHGYSNVLLLTGDKLKHHQNGQDINFSRTRYL
ESVNAVMQSKKLAPEIKVGVALNPFKYTKAEHDAQYYKLDKKVLAGADYVVTQLGFDLDA
LKEAKQYLANQHSKIDLFACVMPLTAARAEFMFKQKVAGIVLTPHLLQLLQQEQSIDAVL
AEQNVYARCALQILICRSWGFAGVHLSACHKPEEQQKLEQALTCFRDLSFDQCMQIWSEL
HQLKSGDELKSKPDVFQEKPSTEQVLKYKSMQFMHDSMFDSKIARNVGSKFFNPKLWSGH
FANKLLIKSEYLSKHGVVGCESCGQCRLADTLYICPETCPKGLANGPCGGTTLDRCEFGD
RECIHSVKARLAQQVDQVDVLKKRMIDTVPIESRGTSSWVNWFNPK
>A0A661A5M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MHRLLKVLAEGPLLFDGAIGTEFYRRGVYLTNNFEELNRSQPHLVRSVHEEYIKSGAQVI
TTNSYGANRIRLERFGLAEHSTEFNLAAARIAREAAGELIWVAGSVGPSGAEGARILGPG
AQEVREIFAEQIDALVEGGVDLILLETFMHLVEIRLVLEVVKERHPELPVVASMRFEPDR
KLADGSEPEAVAAALADWGADILGANCGEGPELVFNVARRMLEAGRPVLAEPNAGTPEVV
EGRSVYVGNPEFFGVYGRRMLKAGIRAVGGCCGTTPAHIHSMRGAVRMLGGGSSWQRTEV
VHAGVTEAETETVDRAPRKPVEERSALAQKMAAGKFVVSVEVNPPLGLDPAPAVKAARYL
VDNGIDVVNTADGPRASVRMNNLAAALAMQQAGIEVLLHICCRDRNLLALQGDLLGAHAL
GIRNLVVITGDPPKVGDYPDATAVYDLDSIDLLRWIDGFNHGVDPTGKRLDDTTNFHTAT
GVEPGALDYDRELRRLERKVAAGADFVMTQPVFDPRTMERFLKDTSDLDIPILLGLLPLA
SSRNAEFLHENVPGMNIPEDVRKRMASAGSGEKARATGVQIAREALLDLKGRVQGAYIMP
PFGRYEMAVQILDGIER
>A0A7C5UHL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MPAERGRELLARLRETIIIGDGAMGTEIWKRGFPQGLLPEQANLTAPDLVKSIHRDYLAA
GAQVLTTNTFAANPLRLHQFGLEKRICELVSTAVQLAKEAISEANADAFIAGSVGPIGQL
KNLLELTDEEIEEAYRQLIVALADAGVDLLVLETFLSVDDLLKVVRVVKQVTDLPIIAQL
AAIDDGERSAEGRAALAVFELEKLGVDAIGTNCGISPIRNLSIVCALARLTELPITASPN
LGFAQYVDGRFIYLGEPKEFARIGEEIWQAGANLIGGCCGTTPEHIHILVQRLKGKSPQP
RTAKRIQVKPEGQPKMKSPMPNFMSKLGIEPIIIVELDPPRGLDYKPILEGAKMLARAGV
NAISIGDNSLASIRLSNLVMANLIQRETGLPTICHFAGRDHNLIGAQSLLMGMAVLGVPA
ILAVTGDPARLAPEVGASSVYDLNSFQIIELLSKLNRGVNWVDTPIGMRTDFIIGAGFNP
NVHNLNAEVKRLKRKIEKGAQFALTQAVFEPELIKACGEVMREVGIPIFVGIGILISARN
ASFWKSIPGVKMPDEVLNRMESAPKERQLAEGIAIAQELTEVALKHCPGVFFIPPFSRAE
YALPLVELVRSKKWETFPVKS
>A0A1B7WF04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabaena sp. CRKS33|TrEMBL
MQNSYSTSTLNNFRTAVAAGDFLITAEVAPPKGGDINHTIEMAATLKGRVHAVNITDGSR
AVMRMSSLVASAILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIQNILALTGDPVKA
GDHPQAKAVFDLEAVRLLQLIRNMNQGVDFNEKPLTDGKLDLFAGAAVDPQSPSWSGLQS
RFEKKIAAGAQFFQSQLITDFEILEKFMDKIACGYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPEHIIERLAKAKHPLEAGIKIAAEQVQIAKQLCQGVHIMAVKREDLIAPILDLAGV
ESVTCHQNS
>A0A4V2SQA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothalassium salexigens DSM 2132|TrEMBL
MTHIDAHAPGLQPSLYADFGEPLKISFEFFPPKTDAMEQTLWQSVKTLEPLGPRFVSVTY
GAGGSTRERTHATVKRILEETDLTPAAHLTCVCHTKDEVKRIAQEYWDMGVRHIVALRGD
APGADYKGDPWAEGYKNGAELVAGLREVGDFDISVGAYPEVHPDSPNLAGDLDNLKRKVD
AGANRAITQFFFETDMYWRYLDHAQSHGIDVPIVPGILPVSNMKTLKRFAAGCGATVPDW
MVELFEGLDDQPMTRNLVSATVAGEMVKRLYAGGVREFHFYTLNRAELTYAICHLLGIRP
QGQAAMIEAAE
>A0A0H3PHC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176)|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHYLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>A0A2N2SEV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-20|TrEMBL
MKTLSSKFGLSFEFFPPKTAEGMDKLRETRTQLAKFNPEFFSVTFGAGGSTRDRTMETVL
EIQQEGYAAAPHISCISSSKAEIRDLLLAYQAHGINRLVTLRGDVPSGEVSSGDFRYAVE
LVEFIRAETGSHFHIEVAAYPEFHPEARTPAADLLNLKRKVDAGADSAITQYFYNADAYF
RFIDQCDAAGINISIVPGIMPIYNITQLARFSSICGAEIPRWLKMRLEEYGDDMVSLRAF
GIDVVSELCSTLQANGVPGLHFYTLNQAAVISNIIENISE
>A0A1E7HSN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium S5133MH16|TrEMBL
MKVKTPSKLEKILAAGHLAVTSECGPPRGSDIEVIKEKANLIKDCVDAINITDNQTSVTR
MCSLVACIQLKLMGLEPVLQMVTRDRNRIALQSDILGAASFDIHNILCLSGDHQSFGDCP
TGQNVHDIDSMQLIQTMRLMRDQAKFLGGDDIKRPPKMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNMEKFELWLKMAGDRGLLEKVYILAGVTPFKSAGMAKYMKNRVPG
IEVPDELVKRMADTPKEKQPEEGVKICIEQIQHLKEVEGVHGFHVMAIEWEEMVPEIVEK
SGLYPRPSVE
>A0A0K6GKV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus suryakundensis|TrEMBL
MGLLDDLKQRIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIEAGAEVIQTN
TYGANYVKLARYGLQDDVKEINKAAVQLAKQAAKGRAYVLGTIGGLRSTNKSTISLEEVK
RTFREQLYVLLSENVDGLLLETYYDFEELQTVLSIARKETTLPIIAHVTLHDIGVLQHGM
PLAEALRQLELLGADVVGLNCHLGPYHMLRSLEEVPIPTRAFLSVYPNASLPQYRDGRFI
YETSEQYFEETARAFRDQGVRLIGGCCGTTPKHIAAIARALPDRTPVYKKEVKQRHTIVV
QEAEQTKQPSLADLARTRRSIIVELDPPKKLGLTKFLEGAKALKDAHIDALTLADNSLAT
PRISNIAVGTIVKQQLNMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRL
EKKIECGAHYFLTQPLYSEKQIKDVYEATKHLPTPIYIGIMPITSARNADFLHHEVPGIT
LSDDIRARMAACANDPVQSTREGLAIAKSLIDAAFDLFRGIYLITPFLRYDMTVELVHYI
HEKERLTKERTVYYG
>A0A7C7RJ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MDLKEVIESTLRMKGYVIACNVTDNPQSFAYISSLAAAYIVQKETGVETIYQLTCRDRNR
LALTSDLLGAAALGIKNVLALTGDHSTLGDMPQAKPVFDLDSVQLIRMIRTMVDQGVDVS
GNEIEKPPKFHVGAGANPNAQPLKPEIIKFAKKVEAGAEFFQTQVVFDIETVKRFFDEIK
GYNVAVLIGIFPLRSYGVAKYFDKTVPGVRVPEELMDALAKAKKISDKKKRKEKYNEINL
EYFTSLLKEIKRTTSAAGCHLMSVGYEEIIPSLVESVR
>A0A523B749|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Verstraetearchaeota archaeon|TrEMBL
MKEAYSTFMRALSGGKFVFTSEIEPKKTTKFDEIVRAANILKNHVVACNVTDNPRAKAHL
SSLVASYVIQRETGLETICQINVRDRNRLALISDLLGASALGIRNVLVISGDHIAGGDNP
GAMPVYDLDSTQFVQMVRGMVDNGTDLNGNPIDGDVRLHVGVVGNPNADPLEVEVCKVER
KIRAGAEFIQTQVVFDVEKAKRFLKDLNLSVPVLIGIFPCKSHRIAEFIVSKIPCISVPK
EYIDRLRSAECQGNATESRKRIDEVNVDYFSNLIKELRETTRTSGIHIMTIGYESIVGKI
ADVVLG
>A0A537DGK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MRPARVGVRQPRHFASWSRQGLAGRLRRPQTFRRCWFQRRIRARCRPRTRFHRKRVLRCR
KIRGTRLYRVSGASAGPSSVRYQDCRGSGENLGEPRLWTSDQNLGCGLREARKRHAWSRT
GKGDIPVRLGDRARRHNLVTVELIPDRVVTSDLALLRGRVDAITVPALRNGHNDPSYPKS
FAITPQRRSLASASIINKAGITAVPSLTCRDCSRLDLSTVSNQVEQGLENVLIVYGDPYP
EPRPGTYEFTKTNELIREVSSLNDGNDPCIGAVTNQHADNREGEISRTISRVDAGADFIV
TNVAFDSESVLDHRDSLLEAGLDVPLFIQVSIPLNLDNVLFVSQKFDIPVPAQVRRKLLE
DPTGGSLAVAADAYEALRGEANGIHFSYLFRQRNPIPTYRHLLEIIGIAGPTLAPLATSP
VKTYPVV
>A0A523W9M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MIIVEQKPLEIIFGMTGNFQSLLIVGCDGCAAIVQTGGEKQAEILKKLLEMHRKLVGKDG
SKIKAVSILRQCDRQIALSSLQLLIGEYDAIVSLACGVGVQTLADLYSNKVIIPANDTMF
IGMHDTKEGKFYEMCRACGDCILFETGGICPITRCAKSLLNGPCGGQASGKCEVEGWKND
CAWILIYNRLKERNKLDLFRKFRIPRDYRISEHPRQLGGEVAQKKEKFGKVEEIVGGAFK
RETHSELMKQISAGKFVFTGELEPVKTTSLHEVLEGAKVLKGHVVAANVTDNPTSFGYMN
ALVPCYMIQREVGLEAVYQMTARDRNRLALLSDVLAAGALGIRNILVLTGDYTTVGDTPG
SKPVFDLDSATFTYMMRKVIDEGVDLKGNKIEDPPKFNIGIAAAPNADPLEAELLKIERK
VKLGVDFIQTQCVYSVEQAKRFADAAAYLKTPILFGVAPFKSTSMMKWMIKFVPGIKVPE
DVKQRLRKAKEKSKDAFREENIEIFGELLREIRKTTNAAGIHMMAIGYEWIVPKIIERSG
IA
>A0A2U2C318|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter skirrowii|TrEMBL
MFETLISKLQDGKYLTLETTPQHEPSMHNIVEKIKKFKIDSRVDGFTCTDNPLAKLKYNS
LFAALKLQTEFKKPVIATMTMRDRNKIALQSDLLGANDFDIRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFAVVNAYAKNFGSLEKKMNLKI
QNGAVGVITQPVFDIENVKKLLESFEIAKENVEGDKKKSQLILGLFPITKLRTALFLSAQ
VPGIHVPQFWIDELERAHSISEEEEYKVGMQLSKNLFKEINKIHPKIHLMTANNKFEVAS
EILD
>A0A3R6QEC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AM46-21|TrEMBL
MKLKEYIQTKRIIADGAFGTYYISLYGDGSRAENGAGLSNLPELANIKAPERVIGIHTEY
IEAGAQFVRTNTFASNTKSLSADMEKVKENIRAAVMCAKMAAGKVDREIYLAGDIGPIPV
EGMLHSDWLTQEYIAIGETLLSQGIDILLFETFPELETILPVVTYLKENHDCTILVHFSV
NQFGYSNTGLSAKRLIAEANACPYIDGTGLNCGVGPGHMEKLIRKIAPDDTTFLSVFPNS
GYPKYLNNRLTFTDNAEYFTEKMEEIAALDVGIFGGCCGTTPEYIRRIAAGISADHPVRK
TETEAEKIIVSEHPAYGFMERRVKEPAHKLIAVELVPPLNANDEKLLDAAHILKNAEVDV
VTFPDSPSGRTRADSVLMAEKIRLETGLCVMPHICCRDKNAIAIRSTILGSSLNHITNFL
LLTGDPVPVLFRQTTKSVFNFDSVGMMKIVQEMNSDTFTDHPVTYGGAINHNRMNTKAET
ERIRRKMAAGATFFMTQPIFSAEQADVIRQMKKETGATILVGLMPLVSRKNAVFMKNEMT
GIEIPDTIIERYREDMSREEGEACGVQIAREFMAVTDDFADGYYFSFPFNRVHMLKKILK
>A0A845LY63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritimibacter harenae|TrEMBL
MQPPRVSFEFFPPKNVEATFRLSDTVRDLAPLDPSFVSVTYGAGGTTRDLTHDVVTTIHR
NYGLNVAAHLTCVNATRAETMEIVDTYAQAGVTEIVALRGDPPKGASGFTPHPDGFANSV
ELIEAIAARGDMNIRVGAYPDPHPEATSDMSDVDWLKRKIDAGATSAITQFFFEAETFFR
FRDKCEKAGIDAPIIPGILPIQSWAGVKKFAASCGTPVPGWLDQAFARAERDGRERLLSV
SYACELCTELMEGGVEALHFYTLNKTDITRDVVHALGVTPRVQLQNVA
>A0A1G0GC23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_37_14|TrEMBL
MKKNVAPYRISFEFYPPKTPDGVHALIQSAQELTILSPAFFSVTFGAGGSTREGTLEMVR
LLQKRTSTSIAPHLSCIGADRVELLEILQQYQTLGVKRLVALRGDLPSGMVSSGDYKFAY
DLVRLIREVTGDYFHIEVAAYPEYHPQAKNAWHDVSNLKKKYEAGADSAITQYFFNPDAY
FYFLDECNKQNINMPIIPGIMPILQFNKLMRFSEVCGAEVPRWLYKRLESFGDDKESIYD
FGVDVLSHLCEQLLLAGAPGLHFYTLNHAQLSMEILTRLNLIALSQIEV
>A0A366N2B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp. FW59|TrEMBL
MFETLIKKLQEDKYLTLETTPQHEPSMHNIIEKIKKFKINEKVDGFTCTDSPLAKLKYNS
LFAAVKLQQEFNKPAIATMTMRDRNKIALQSDLLGANDFDIRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFSGRPFKIEPKQIFPFGVVNSYAKSFGSLEKKMFLKI
QNGAVGVITQPVFDIENAKKLLESFDIAKEGVEGEKKKAQLIFGLFPITKLRTALFLSAQ
VPGIHVPQFWIDELEKAHNIGEDEEYKIGMKLSRDLFNDINKIHPKIHLMTSNNNFNLAN
ELLS
>A0A2N6KC53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fischerella thermalis CCMEE 5268|TrEMBL
MLIFMLDTQNPTSLTSFRTAAKAGQFLITAEVAPPKGGNPEHMLKMAATLKGRVHAVNIT
DGSRAVLRMCPVVASAILLQHGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALTGD
PVKAGDHADCKGVFDLESVRLLQVIQKLNHGVDYNDKPLNDGALDLFPGAAVDPQCPSWS
GLQKRFERKLEAGAQFFQSQLITDFEILEKFMDKIAADCGKPILAGIFLLKSAKNALFIN
RCVPGVNIPQHIIDRLAQAKDPLEEGMKIAAEQVQIAQQLCQGVHMMAVKREDLIPQILE
MAGVTPVNQMVSL
>A0A0Q5K4J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus sp. Leaf326|TrEMBL
MTRISLELVPRSRSGLRAELATVREHFPGVDTVNVPDLTRFSTRSWEGCAFARPHLRAIP
HIRAIDLNPKEPLPMSGLLLAHEIDEVLIVTGDAPSDMTRRVYNVDAEAAIRRFRRELPH
VRVYAGLDPYRQSFARERDYLERKLEAGAVGFFSQPFFDLRLMDTYADLLPDGAEMWWGV
TNVTTEGSANYWSSRNNAVFPRSFDLSLEWNRTLAAAALQFARDRGQHVYFQPIRTDLRE
YLEGIL
>A0A1Y5NC75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter concisus|TrEMBL
MLKEKILNKEKGLVLYGLTPPKAEFEEAKLREISERWSGRINDIKADGLVLYEVQDESER
NDSERTFEFSGTLSPEIYYKKYLNVATPSIFYRVASGYGEDEFRAALKAQSSNLNVLVGA
TSSTQKVRLNLARAYEIASEFKELAVGGVCIAERHGKKGDEPQRMREKIAAGAKFFISQA
IFDAQLARKFLEDCAAAKISEPIFLTFSTAGNAKTLEFIKWLGVSVPSSVEERLNLSSDY
LASSCEIIKEIWCELKKFGDENGLNLSINIESVMAKRAEIEASLELTHKMREVL
>A3SLR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM)|TrEMBL
MTTPAISFEFFPPKTLEASFRLWDTVQTLAPLEPRFVSVTYGAGGTTRQLTREAVETLHK
SAGLKVAAHLTCVDASRSETLAIADDFARAGVTDIVALRGDPPKGSGGFRPHPDGFEDSC
ALISALADTGRFNIRVGAYPERHPEAADDAADIDWLKRKIDAGASEAITQFFFEAETFLR
FRDRCAKAGIDAPIVPGILPIENWSNTRRFATACGTGVPQWLDDAFDKATRDGREDLLAT
ALATELCSDLLEEGVETLHFYTLNRPELTRDICHALGVTPKVKLRDVA
>A0A2N2XS63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-22|TrEMBL
MHIDEILTTTRKTLFSFEILPPLKGGTFEEIHQSIEPLLEFKPPYINVTYHQEEVVYKHR
DGGLLEKKIVRKRPGTVGIASALQYNCRVDVVPHIICGGFTREETENALIDLHFLGIHNV
LAVRGDPERSQKEFIAEPDGHTHAVDLVRQIIDLNHGRYLDEELQNSTATNFCVGVAGYP
EKHAEAPNQHSDLRHLKEKVDAGANYIVTQLFFDNSKFFDFVDRCRAAGITVPIVPGLKP
IAVKSHLIGLPKTFHIEIPDELVHLVEQCKSNREVRQVGVEWAITQTKDLIRAGVPAVH
>A0A7L4PEQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanocellales archaeon|TrEMBL
MKVIEFYRNPPVYSLEVFPPRNGGSLDRVYNTIDSLIEFKPTYVSVTCGASGTPRGGTLS
IAAKIKRDYGIESVVHLTCADKSKQDIENLLMDVKYEGIENILALRGDTPQGENTFQPHE
NGHRYASGFVEQISLMNEGKYLTEVEGVYVKGLPTNFGISVAGYPEGHPECSDAKKDLEH
LKIKVDKGADYIITQMFFDVSHYLKFVKNVRRIGIDVPIVPGVMPLEEYSQIIHMLQKMK
ISIPQDFMKKLEKNKYDKPAVQKICTEHTLSLCKT
>A0A7G9GHX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium NSJ-29|TrEMBL
MYERTALSFEVFPPKTDKGMAKLPDTLDHLYKFNPDYISCTYGAGGSNVGKNMDVCKLIL
NAENETVPVTHFTCIGHTRETVKEQLQNYLDNGIDHMLALRGDLPYGWTGTNGDFAYATD
LVAYVRKEFGDKFEIAVAGSPEGHIECRSLEADIAHLKQDEGADYIMTQLTFDMEQFKYW
LDAIRMAGITMPVDVGVMPVVGKDAVINMCLSRNGCAIPRELAEVISHHWFDKDPDGNDL
PEVKAAFREEGIEYTVDQLHEYMSLGVEGIHLYALNKWEDVTEILNRAGIRTVV
>A0A1Q7LRY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium 13_1_40CM_3_65_8|TrEMBL
MPTDFRSLIADGRVHVFDGAMGTMLYGKGFFLNVCYDELNLKQPRLVQEVHAEYVRAGAE
ILETNTFGANPLKLNSYGLADDTEKINRTAAELARAAAAGGGGRASVVGAIGPLGIRIEP
FGPTSQAEAQALFARQVQGLLAGGVDGFVLETFSDMQEMHAALNAVRAATDLPVACQMTI
GTDGLTYYGTDPETFTKQLTAWGADVIGVNCSVGPAGVLEAVEKMVKATDKPISAQPNAG
LPKDVGDRKIYLASPEYMASYARRMIEAGARFVGGCCGSTPEHIKKIRDYVASVVPRQPS
VVVSRAQVKAPEGVTATPLALKSGWGNKLARGELVTSVEIVPPKGVDPTPMLAQCRALKA
AGVDAVNVPDGPRAQSRMGVLPSALLIEREVGIETVIHYCCRDRNLLGMLSDIIGAHAAG
LRNILIITGDPPKMGPYPEATAVFDIDSIGLTNLVYRLNQGLDPGNNPLGGATKWAIGVG
VNPGAGDQDRELSRFAWKVDAGAEFAVTQPVFDVRQLEAFLKRIDQFKLPIVAGVWPLIS
LRNAEFLANEVPGVSVPEEVLQRMRKAQEQGKEAALAEGVAIAREMFTRVKQMVQGVQVS
APFGRVEVALQVFQ
>A0A7V9LM52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MVAVDADSGPAKGQGLTVNASFEFFPPRTPEGVVKLRAVRRELATLKPEYFSVTFGAGGS
TREGTWNTVVEMQDEGLPVVPHISCIGTTRESVRTLLAGYRERGVRRILALRGDMPSGAA
GGAGDFRYANELVEFARAETGDWFHITVAAYPEYHPQSHSPAADLQSFIRKVNAGADSAI
TQYFYNFDAYARFVDEASALGCNVPIVAGVMPIVSYTQLARFSDSCGAEIPRWIRRRLES
FGDDRESIRAFGLDVVTNLCEQLLAVGVPGLHFYTLNQAEASVELWKRLDSQAS
>A0A7L6YLX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter sp. RHB21-C01|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAL
>A0A7Y5HVE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MTSANTPSTGVPVSFEFFPPKTPEGADKLRAVRQQLYALRPEFCSVTYGAGGSTQEGTFA
AVREILAEGVSAASHFSCIGATRQSVREQLATLKAMGVQRLVALRGDLPSGYGMGGEFHY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLKAYVTKVQAGADAAITQYFYSAD
AYFRFVEDARRLGAEVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDVASI
RAFGLDVVTSLCDRLLAAGVPALHFYTMNQSVATLEICRRLESLLGKRT
>A0A1Q6RS38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:552_39_19|TrEMBL
MAKKVFAKKDIRAFLHTQKLITDGAFGTYFSSICQNGIFPERANTQAPALVKQVHEAYLS
AGAQLIRTNTFAANTKTLDMGLDEVLETIEAGFTIAKEAAEPYRQKHPVFLAGDIGPIPG
GRQEQEEEITEEYLQIARKFVALGADLLVFETFPNPDQILPVIRQIRKESPIFILVQFTV
NQLGYSVAGISARSLLEEAGQVTEIDAAGLNCGVGPGHMYNIIKQVSSLSGKYLSVLPNA
SYPKVVQDRLVFLENMDYFADKMVEIADLGASIIGGCCGTNPDYIRRLVKALGEKHLRAE
KPSPVHITVKERTEQAEDHSFYAGKSGKLIAVELSPPPSANDQKLLEAAHLLSAMHVDTV
TFPDSPSGRTRADSILMAAKVARETDLCVMPHICCRDKNAIAIRSQLLGAYLSDIRNALV
ITGDPVPSMAREDVRSVFNFDSVGLMKLVQEMNREEFASDPFFVGGAINQNRLRLDVEIN
RVKRKMEHGATFFMTQPVFTKEEIDKIRRIKEETGARILCGIMPLVSRKNALFIKNEMTG
MCVTDEIVARFADGMSRSEGEAAGCAIAREMMALAADFADGYYFSIPFNRVYLLHDMTGV
INESGKEK
>A0A7W9BMJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Loktanella ponticola|TrEMBL
MSLPNVSFEFFPPKSLAGSFRLWDCVNTLAPLDPTFVSVTYGAGGTTRQLTHDAVTTIHR
TSGLNVAAHLTCVNATKAETLEIAQSYADNGVTEIVALRGDAPQGETTFSAHPDGFASSV
DLIAGLAETGQFNIRVGAYPEKHPEARDQAADIAFLKRKIDAGASSAITQFFFEADTFFR
FRDACVKAGIDAPIIPGILPIENWTGAEKFANRCGTSIPQVVRDAFTNATRDGTTDLLAT
ALATELCDELLTGGVNDLHFYTLNRPELTRDVCHALGITPKTQLQNVA
>A0A523XRU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division TA06 bacterium|TrEMBL
MQPFREFLKKNLVLFDGGNGTEFYKRGVFINRCFDELNLSDEAMVTDVHKQYIEAGAEAI
ETNTFGANRLKLSKHGLDDKLFEINHRGVEIAREVTQGRAYVAGAIGPLGIRIEPWGKTA
REEAREIFKEQAKALLEGGVDLFLLETFLELSPLEQAVLAVREICDLPIIAQLTIREDSS
TPFGTPVEMYTKEMSSWDVDVIGLNCSVGPEAMLEAVEAMAARTKKPLSTMPNAGKPKEI
EGRNIYLSSPDYFAEYARRFALAGVKVIGGCCGTTPKDIRAAKAAIKALKPVEHGGQWKQ
VTVEAAPVKLVPQVEKSGLARKISKGEFVEVVETTPPRGCDPSKVLKAAKALMEAGIDAV
NIPDGPRASSRMSPLALATTMERETGIESVLHYCCRDRNLLGMQSDLLGAYTLGIRNLLL
ITGDPPKLGDYPDATAVFDVDSIGLVNVVNRLNHGRDIGDNAFGDPTGFFIGVGVNPQAH
NLDYEIRRFWYKVDAGAEFAITQPVFDPEALLSFLEKISHCRIPIIAGIWPLASLRNAEF
LRSEVPGIYIPDSVMERMKKAEERGEAAREGISIARESLLEVRDSVQGVQVSTPFGKYER
AIEVIKAMRDDE
>A0A7C2E3H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MHAFLERLEQGVLVADGAMGTQLYARGVPFDHCFDELNLTAPDLVRGIHLDYLVSGAELI
ETNTFGANRFKLAAHGLVGRLEDLNAAGARVAREAAATAGRPIFVAGSMGPIGRPMAPLG
TVSPDEVREAYAEQARALVAGGVDVLILETFTDLAELLEAVRGVREAVSVPLIAQMTFTQ
DGRTLLGHGPREIVAALERHQVDVIGANCSVGSQGVLEAMEQMAAVARRARLSAMPNAGF
PSYVGGRYIYVSTPEYMAGHAVRLAALGVRIIGGCCGTTPEHIARMRAALRDPATVASLG
EAKAGSRWTLGAPVIEPEPVAVPPGSPSGLGQKLGRTFVVTVEVNPPRGVHDHREIEACR
RLREAGVDAIDVADNPMARLRMSPWAMSSRIQSEVGLETILHFTTRDRNLVRLQSDLLAV
HALGVRNILVLRGDPPQIGDYPNATAVSDVTPSGLVKLIKEFNRGRDVAGNAIGTPTAFA
VGVALNLSAANLDQEARILDRKVRAGADFICTMPVYDPEALDRFERLAGRVPLPVLVGVL
PLAGARHAEFLHNEVPGLSVPEAVRARLRGARDGREEGLRMAEELIGHLRRRAAGIYLIP
SFGRYDTVIDLVRLAKRSHRSSVVDER
>A0A1V6FPV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium ADurb.Bin082|TrEMBL
MTEKELGDALRRALMVFDGAMGTEIYRRHVFTNRCYDELCLSEPGMIADIHRSYVAAGAD
VLTTNSFGANRLSLSAFGLGERVAAVNLAAARLAREAADQAGRPLLVAGSLGPLNTLGNT
SAERIQCLAEQAAALVAGGVDFLMFETLPSPEAAQEARAAVDSLKQPVAFVLSHSVPADG
DVESAVRHRLTDWAAFPGPIPAAMGFNCCVGPDQMLSVVEVAVRCCELPLIIQPNAGTPR
NVDHRQLYLCSPEYITEYARRYVNLGARGVGGCCGTTPEHIREMARAIKPMTKSHVVALR
VDAEKTDAVPEMPLAERSRLGRKLAAKEWVTAVEMTPPRGWDTSQIVARARLCHDRGVDT
VNIPDGPRASPRMSPLITAAIILRQADIEPVLHVCCRDRNYLGLQADLLGSAAAGIRNLL
MVTGDPPKLGSYSFASGVFDTDSIGLVSLQKHLNRGLDLGGQKIIPPTAAVIGVGADPNA
LDFDREVRRLREKAAAGADYVTTQPVFDPEALFRFLDEIDDLGLPIIAGIWPLASLRNAM
FMKNEVPGVTVPDWVIERMTKASTSEEQLATGIAIAREAIDAIRDRVSGVQVSAPFGKVE
IALATLNAEC
>A0A7V7X6X8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MSPSQAFPVSFEFFPPKTPEGADKLRGVRQQLYVRRPEFCSVTYGAGGSTQAGTFAAVQE
ILAEGVSAASHFSCIGATRASVREQLAQLKAMGVQRLVALRGDLPSGYGIGGEFHYASDL
VAFIRAETGDDFHIEVAAYPEVHPQARSAEADLQAFATKVRAGANSAITQYFFNADAYFR
FVHEVRRLGLDVPVVPGIMPITGASQLMRFSDACGAEIPRWIRLRLQGFGDDTASIRAFG
LDVVTELCEQLRRGGVPGLHFYTMNQSAATLAICERLGI
>A0A379HIQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia stuartii|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRTEEMEQTLWKSIDRLKNLKPKFVSVTY
GANSGERDRTHSIIKDIKEKTGLIAAPHLTCIDATRDELREIARDYWNSGIRQIVALRGD
LPDNSRKPDMYAADLVELLKAEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPSWMSRMYE
GLDNDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A1C5XDS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Bacteroides sp|TrEMBL
MKVIDLIHNNKKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELVKEALKCKTDAEAEQVGIEWCVAQCKELMSHGVPSIHF
YSIGAVDSIKEVAKIIY
>J9ZBX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospirillum ferriphilum (strain ML-04)|TrEMBL
MTFREALNAREFLVTAECSPPKGTRIDGLLDRLTPLKNRIHGINVTDNQTGVMRMCPMAM
GLHLKGIGLDPIIQITLRDRNRLAIQSDLLGMSSLGLSQVLCLTGDPPKLGDHPEAKPVF
DIPTQELIRAITLLNGGTDLSGKDLNGKTDILPGAACSPEGDQETEFRKFEEKFDAGARF
FQTQAVFSPEKMEEFMRFASPFSVPVIAGIILLKSAKMARYLNDHVPGITVPPPLIERLD
KCPPGQALESGIAIAAETIRAIRPLVHGVHIMTVGAEETIPRILDQAFG
>A0A0M1JX90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktothricoides sp. SR001|TrEMBL
MTAQTPANLSQSEPAVSRFAAAIKAGEFLITAEVMPPKGGDPKDMLEMAQGLKNRVHAVN
ITDGSRAVVRMSPVVASAILWQNGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALT
GDPVNAGDHPDAKSVFDLESVRLLKLINSLNQGFDWNYNPLTNGPTNLFAGAAVDPQSKS
WSGLQSRFEKKVEAGAQFFQSQLICDFDRLDKFMLEIAAGSNKPILAGIFLLKSAKNAAF
INRCVPGVNIPDSMISRLANAKNQLREGMLIAAEQVKMASQICHGVHLMAVKREDLIPEI
LDLAGISPL
>A0A353C0G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MRIKEIYLQKSPVLSFEIFPPKPDYPLDTVFQTIEGLKDLHPDFISVTYGAGGSSRARTI
EIAARVKRDCQIESQAHLTCVGHSPAELDAIISEIGAEGIENILALRGDPPRDQPNYNPE
PGYYRDSIELVKHIRSKGGFCIGAAAYPEGHVGTTRWEQDWLRLRDKVEEGVDFLLTQMF
FDNRVFFNFQENMLRLGVKIPISPGIMPVLNINQIKRMINLSAASIPAKLLMMFDKYGDN
NKDFEKAGIEYAINQIDDLLANGVAGIHLCTMNKVEQTRMIVEDSQLGARYK
>A0A3E0LAA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis flos-aquae TF09|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSKSGLQRRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPVLAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPVHN
>A0A1A2YP29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium colombiense|TrEMBL
MPADSGCPKRMEYGPCGGVRPDGQCEMRPGPCVFDDVVPWSGHRPAPRPVSAPRVLTDFS
ATPFDPDDIAATAAILASGCDAVLVGEHQNKPDFPPTLMASLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSIDVDTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGMTAAVP
ETPTAPPVHHRPARLVEKQCAGASLAVLNHVPFPDMVADFMRKAQSAGLTIPVIAAVAVF
TDSISAAVLEGLPGLELDPAVTQRVLSAPDPVATGIAAAVSEARVLLSIEGVEGVNLSGL
ASASGPRVGAQIKAEVGRRILAGERRL
>A0A2E2XYX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentimicrobiaceae bacterium|TrEMBL
MALTVLQHIEKSKGTLFSFELLPPLKGHDFESTEQSIEPLLEFKPSFINITYHQQEVVYE
NAGKGLMRKHTIRKRPGTVGIAAAIKYRYGINVVPHIICGGFTKEDTENALIDLQFLGIN
NLLVVRGDPQPGAKVFIPEPNGNEHSSDLIEQIVNLNNGIYIDNKLENTRSMNFCIGVAG
YPEKHSESPNIDSDIHFLKKKIDAGASYIVTQMFYDNNKYFEFVKLCREKGINVAIIPGL
KPIATKTHLKNIPKTFNVDLPVDLVKEVIKCKDNKSVRQVGVEWATQQSKELKAANVPVI
HFYTMGKSDNIQKIAKAVY
>A0A3N5HTR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcaceae bacterium|TrEMBL
MKIRNRLNPSDPCFSFEFFPPKTEEGRRTLLRTVEDLRPLEPGFVSVTYGAGGSTQERTV
DLVRQIRATGLETMAHLTCVGHTREELGQLVEQFLTMGVENILALRGDPPSGQREFQPLP
GGFRYAAELVRFIRERDHTLCLGGAGYPEGHVETPLRDDDLRNLKAKVDAGLDFVITQLF
FDNAFYFDFVERARRLGINVPIVPGIMPITNIEQLERFVRLCGATVPMRLVLQLERYRDD
PDAVVQLGVAHATVQCMELLARGVPGIHFYTLNKSPATRLIVSALKGRGAGPAAPPGAPP
PTR
>A0A432IIG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MVWNPEGSVVLEVLPPTLKSGLEGLHRRLSRVRRLIENGDFDAVNIPEIHDEENRNDRGH
RRHEYSARMQPRELGRRIQDELGIPAIVNHVVSFDPADQFLDWVNETVQGHDIHNLVLVG
APHDRRQWPGPAVGEANQLIRQQFGSSEVCIGNICIPQREDSPISEAVRMEQKVQDGADF
FSTQIIFDAADIISLLSDLQVQAPNACGVPLLVSLCPVKRIRQLGFLRYLGVRVPDHLDS
LLATVPEAYCLDLSLEILSNIQGTLIDHQQQHQSGPLLGWNIAPVGPIPIDAIEILMDRL
PGSIRS
>A0A4R7Y5C8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas alkaliantarctica|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARNPRFFSVTYGAGGSTQARTREVVR
AVGESGINTAPHLSCIGSEKAQLRDLLVQYREEGVESLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVKQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLEGGAPGLHFYTLNQAAPVLKIVDNLTD
>A0A494XMS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trinickia fusca|TrEMBL
MNPIEISFEFFPPKTPEGVEKLRVTRAQLAQLLPSFVSVTFGAGGSTQQGTLDTVLDMSK
DGLQAAPHLSCIGSSKESLRAILARYREHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFWIEVAAYPEYHPQARSPRQDLENFARKVKAGANSAITQYFYNADAYFRFVD
DARKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWIARRLESFGDDREAIRAFGLDV
VTQLCQRLVKEGVPGLHFYTLNAAMATKAICERLGYGRGS
>A0A1Q4GCU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. 40-24|TrEMBL
MKIIDHIQNAKGKTLFSFELLPPAKGQGIQSIFKTMDELMEFKPPFIDVTYHREDYIYKE
HASGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDADFIPTDGGHAFATDLLEQVTDMNKGKYLHEDIITSEKTDFCIGVAGY
PEKHFESPNFNTDFKYLKQKVDMGAEFIVTQMFFNVEKYKEFVTKCRDNGIHVPIIPGLK
PLTTKKQLVTLPRIFHLDIPEELSDAVAACKTNADVRQVGEEWLVQQCQELIKFGAPVLH
FYTMSNPGPTKKIVEKLA
>A0A2T8I002|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panicum hallii|TrEMBL
MMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDKFVQVEGGFACALDLVQHI
RAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYTNDLAYLKRKVDAGADLIVTQLFYDT
DIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTKIPAEITAALDPIKDNEEA
VKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALAILMNLGLIEESKVSRPLPWRPPT
NVFRVKEDVRPIFWANRPKSYITRTLGWDQYPQGRWGDSRNPSYGALTDHQFARPRGRGK
KLQEEWAVPLKSVEDISERFTNFCEGKLTSSPWSELDGLQPETKIIDDQLVKINQKGFLT
INSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLELFCAKEKLDQLVEKIKAFPSLTYIAVN
KDGESFSNVPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWTRGWGCLFPEG
DSSRELLEKVQKSYYLVSLVDNDYIHGDLFAAFKEI
>A0A372UJ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium AM25-17|TrEMBL
MKIIDKLQENKIHISFEIFPPKTDAGIEAVLSATEQIAKLAPAFISVTYGAGGGTSKNTV
QIASDIQKKMGVTSLAHLTCASSTKEEVLSVVDRLRAEGIENILALRGDIPEGREFPETD
QYHYAYELIREIKKQGDFCIGAACYPEGHVENEHKEDDIAYLKQKVDCGVDFLTTQMFFD
NAILYNFLYRIREKGITVPVLPGIMPVTNSRQMTRICKLSGTVLPQRFHAILDRFGEKPE
AMKQAGIAYATDQIIDLIANGIDHIHIYSMNKPEVAAAIMTNLSEILR
>A0A1R1M3P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tersicoccus sp. Bi-70|TrEMBL
MARPASNPEASLHLIEGFSLEMTGKDVPSLMEAKDRIPAGTRINVTFLGNEDLDMRVAAA
SAVREHGFVPVPHLSARRLKSRDELEEFLGRLQEVGASEHVFTIGGDPATPEGPYEDSLA
VITSGVLQRYGVREVGIGGYPEGHPDIAGDALSGALRDKAAALKDAGLDAVVVTQFAFDI
DPVVAWIDTLRSAGIDAPVRVGTPGPAGIKRLLGFARRFGVGANAMIVKKYGFSLTNLMG
EAGPDRFVDDLAATLAERTPGTGLPGEVGLHFYTFGGLGATADWATRFATERSTQSAAQR
SAGDPADRG
>A0A101VG97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium BRH_c42|TrEMBL
MTMAPDNSAQGRADALVTPLFAALPGDPAGDLNVSFEFFPPKSEKMEQQLWHAVEELKPL
APGFVSVTYGAGGSTRERTHNTVARIIAEARLPAAAHLTCVDSTKGEIREVAERYWEAGV
RHIVALRGDAPSADGSPGARFAPHPQGYRDAAELVAGLKQIADFEISVAAYPEVHPDAAS
AEADIDNLKRKLDAGATRAITQFFFEAETYFRFRDALAKGGIDAPVVPGILPVTNVAQAR
RFAAACGAQIPAWMDGLFEGLDERPAARQLVAATVAAELCRRLHAGGVRDFHFYTLNRAE
LAYAICHLLGKRPIGEAG
>A0A7Y8HDA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MAQSFGEVLKSGEFVVTSEIGPPKGWQVSKMIHHIELLKDRVHALNVTDNQSSVMRFPSL
GGAILVKEKGGEPILQMTCRDRNRMALQSDLLFAFSRGIRTVLCLTGDAVTVGDHKTAKS
VFDLDSTQLLKAIRTLESGKDMGGNALDGAVEFCAGCIVTPEARPLEPQLLKFEKKVACG
AEFFQTQAIYDLDNFRRFMDYARRFPAKVLAGIVLLTSARMAKYMAENVPGIFVPASLIE
ELAGAPKGQALAKGIEIAGRMIRTLREERICDGVHIMAIGREEVVPQILQEGGLGPPAGT
PLSPSPSVHSTA
>A0A7Y1ZXD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ilumatobacter sp|TrEMBL
MGRISHKLALGRTLSFEFFPPKTTAAALTLGRTVAELATLQPDFVSVTYGAGGSDRHRTG
DVVGWMRKDTAIEPMAHLTCVGHTRTDVAALLVEYRRTGVENILALGGDLPADGSPVAGD
YRYALDLLNDVATTGCFSVGVAAHPEVHPRSPSRASDRRHLAEKLRIADFAITQFFFDIE
HYLRLVDEMAAEGIDKPIVPGIMPVTNVAQISRMAAMSGAAVPRWLTDRLAAADSPAEIR
KIGIDVASKLCTDLLAAGAPGLHMYTLNRADVTRDIHLNIGSVLV
>A0A7Y8IDH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MNFKESLDSGRFVVIAEIQPPKGNDLSEVFQSAELLRGRVTAINVPDLQNAIMRLGSLSL
CALLKAKGMEVIFNLSCSNRNRLALQSELLNASALGLKNILLLQGDHPSIGDHFEAQPVF
DLDVMGLLGAAKRLQEGYDLMGNDLKGKPQFFTGTQINAAAKGHVLDLEVMDMEKKIRLG
VDFFFTNPIYEVSLFENFIKKVAHFKVPIIVGITLLKSVGMARYINKHVEGASIPEALID
RLMKASDKRQASVEIAGDLIKELRPLCQGVQIIPIGWEDLIPSVLDYAGL
>A0A7Y8IYU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MSLQENLKNKKFIVTSEIQPPIGTGVQDLIRNVERIRGRVDALTVPELKIEGLVTDTMGT
CQALKEQKFDPILQTTCREKNRVEIQEHLIRASESGVENILTFTEDYRITGDSLQEIMFF
HVDTGKLFSVIESLHGGRDISGKDIRTKPKFFVGSGIDSSWGKKVPDLELKEMEELAGLG
TQYFLTTPIFDLDSFNEFMKKVGPIKIPVIAEIILVRSAEMGLFLNKHVKPGMVPNHIIE
KLAKSPDKEKASIEIVSDLVKGLRDLCQGVHFIPIGAEDRISKYLDAAKLSSL
>A0A7Z2FUE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter asburiae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKGVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A7Z9WGS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MKSGSNLEKVLESGQFAVTAECGPPKGTSARVIQRKGELLKDYCDAMNVTDNQTAIVRMS
SLSGCILLIQMGIDPVMQMVVRDRNRIAIQSDILGAVALGIRNVLCLSGDHQRFGNHPTA
KGVYDIDSIQLIQTLKTMRDEKRFLCGENISGEVPLFIGAAANPFADPFEFRVIRLAKKV
AAGADFIQTQCVFDIGKFGRYMSMVRDKGLHEKVHILAGVTPLKSVGMARYMRDNVSGIS
VPDEIVARMEDAKDAKEEGMNICLEIIDQIKEIEGVHGIHIMAVAWEDIVPTIVNKAGLL
PRPIV
>A0A537INB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrabacteria group bacterium ANGP1|TrEMBL
MPRSELRSHPFLARLDQGVLLADGAMGTLVYARGVSFDQCFDELNLSRPELVRQIHLDYV
ESGAELIETNTFGANRFKLGQHNLAHRVAEISHAGAALAREAAGTANRQVFVAGSMGPIG
RPMAPLGAVTPEEVRSAYAEQAAALVEGGADVLILETFTDLNELLEAVRGVQETTTVPLI
AQMTFTQEGKTIVGHEPREIVRALEQMGVEVVGANCSVGSQGILDVLQQMAASVTRARLS
AMPNAGFPAYVGGRYIYFSTPAYMAGYATQLAAVGVRVIGGCCGTTPEHIAAMRHALAEP
VARAADLTIPAELRSSRPAEPEPAARPQTPTPLAQKLGRTFVVSVEIDPPRGVHDRRELD
GCRRLKDAGVDVIDVADNPMARLRMSPWAMCARIQSEVSLETVLHFTTRDRNLMRLQSDL
LAVHALGVRNVLVLRGDPPQMGDYPNATAVSDVKPSGLVRLIKKFNQGHDVAGNAIGTPT
GFTVGVALNLAAPDLDREARILERKMAAGADFICTMPIYEPEALDRFERIMGGLPRPALI
GVLPLVSHRHAEFLHNELPGFAVPAWVRDRMRLAADGRQEGIGVAHELMEAVRSRVGGVY
LIPSFGRYDGVLELVRLARQPAKT
>A0A0N0L7H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. RIT-PI-q|TrEMBL
MAIRSQLFEGGSLEATAKDVFAFPHARATMLQGVTVNIAFIGNETFYDRLNAIDSLLTLG
ARPRPIISARRIASREELGSILSRSTEERGVREVFLVGGDPSTPKGPFIDSMDIINGNFL
NPKAIQTVGITGYPEGHPHIEDEVLWTYLKLKVNTLLALGFKVEITTQLSFDINTVVTWI
EQVRSEGIHVPIRVGIPSPTSIEGIINFARICRVRTSVNLLQRFGWQLTSILSRVGPDRF
LDSLFLETQRRDLGEIRLHMFPLGNLFKALTWFQKYGCGT
>A0A4Q6C094|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium|TrEMBL
MAGVPVSFEFYPPKTDEQRTQLDRTAEKLKAHSPEYVSCTFGAGGSTLSYTSETVRHLNQ
THGFDAAPHLSCVGGSREEIRELLRLYRALGCKRIVALRGDLPSGMGHPGDLRYASELIE
FIRAEHGDAFHIEVGAYPETHPQADDALVDLRHFKAKVEAGADGAITQYFYNADAYFHFV
EQVRKLGVGIPIIPGIMPISNYSQLRRFSEACGAEIPRWIGKRMQALGDDADGIREFGAD
VVAGLCRRLIEGGAPALHFYTLNLAKPTNAVLARLP
>A0A2M9QRU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas lactitubi|TrEMBL
MTAISFEFYPPKTDEQRTQLDRAAAKLKAYAPEYVSCTFGAGGSTLSYTSETVRHLNQHH
GFEAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYASELIAFI
RAEHGDAFRIEVGAYPETHPQAQDALLDLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VQRLGVQVPITPGIMPISNFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGAEVV
AKLCQRLIEGGAPGLHFYTLNLAKPTVSVLTLLRG
>A0A255RBY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula sp. MGV|TrEMBL
MTSTTKLSDHFRSGGCPISFELFPPKTEKGMQLLEQNVERLNQFKPAFFTCTYGAGGSTQ
SKTLDVVERVAKITGLPVATHLTCVGSTVEQLCDYLREAKRRGADYIVALRGDPPQGSDE
FQAVEGGLRYANELVELIRKEFAQEFGIAVAGYPETHQEAVDAKTDLENLKRKVDAGADI
VVTQLFYDNDDFYRFRDECDRLKIDVPIIPGILPVTNFQQAERIAGLCKARIPESLTNAM
NVADCDEEQFAIGVEHAREQTIDLMNNGVAGIHYYVLNKSEAAEKMLEGLSLGQTS
>A0A1F9MV27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca sp. RBG_16_58_9|TrEMBL
MAVFGVPDNEHARMLLSPLAAGRAVREVGGDPLLHLTCRDRNRLALESDLLGAAALGLEN
ILVVSGDYVTLGDHPQAKPVYDADSVQLLQIARGLMEGHDSAGWPLSGSPAFYLGAVVIP
QAEPLVPQLIKFEKKVAAGAQFFITPPVFDLEKFRQFRQMLPPHPVKLLASVKVLSAEEV
AQAAAGQWRQVYSIPPEVVQELSGLGPEEVLAKGAEVAGRLLKQIKAAGLADGVCVKAKG
RSDLMAMVLEAAGV
>A0A1W2BL98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Primorskyibacter flagellatus|TrEMBL
MTRPEISFEFFPPQNLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLQVAAHLTCVNATRDETLGIAREFAAAGVSDIVALRGDPPKGADRFERHPGGFADSC
ELIAALRDTGDFTIRVGAYPDKHPEAADAAADVAWLKRKFEAGASEALTQFFFDIDSFHR
FRDDCAAAGIDTSKIVPGILPIENWKGAVRFANRCGTPVPQWVIDAFETAERDGREDLLA
TAICSEMCSDLLDAGVDKLHFYTMNRPELTRDVCHAIGVTPEVRLENVA
>A0A1Q5DKG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02058|TrEMBL
MALGTPSTRTDHARTVRELLATGEMSYSFEFWAPKTEKGERNLWNALRRVEAVGPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVDHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVRYAADLVRLIKEAGDFCVGVAAFPEMHPRSSDWDSDIGHFVD
KCRAGADYAITQMFFDPESYLQMRDRVVAAGCDTPVIPEVMPLTSVKQLERFAQLSNASL
PSSLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>D6BEL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum subsp. animalis D11|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDILSIEKPDYISVTYGAGGNTKGRTV
EIADRIKRQNGVESLAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEKGD
FNYARELIEYIHKKKGDKFSIGAAYYVEGHRETNDILDLFYLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINIPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPP
ALKEAGLAYAIEQVVDLVASDINGIHLYTMNKPETAKKIIDATGIIRHE
>A0A5W5KLP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella ordonez|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A328UB21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus montanisoli|TrEMBL
MKPDLREALGARILTGDGAMGTYLYGMGFPVGVSYEEFNVLRPEVIADVHRRYYEAGARV
IETNTFSANLASLSNYGLDNQVEAINRAGVQIARAAVGSDAYIVGAVGSIRAGKRRNIGM
QQLEQLFAQQIDALLGAGADGILLETFYDLEEALLALRIARKLSNVPVLCQFAVEKEAVT
LDGQPLAAAFDRLRQEGADVVGFNCRSGPNGILRAIDSIVGDVELPLSVFPNAGIPDYVD
GKYKFSATPEYFAESARKFADRGARIIGGCCGTTPAHIAAIAKALDGYAPQPVEADAVQP
AVQPEAIVVQPAVAPEPGPIKAAEAGGIIEAEPNIVELVKQRHTVIVELDPPRDLNIQKF
MDGAKALKACKADAVTMADNSLAVTRMSNIALASLLQQQVGIRPLVHIACRDRNLIGTQS
HMMGLDALGIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGVAFSGKPLKQ
KANFITGAAFNPNVKYLDKAIARLEKKIDSGADYIMTQPVYDNELIIRIAEATKHLSVPI
FIGIMPLASGRNAEYLHNEVPGIQLSDEVRKRMAGLEGEEGRAEGVKIAEELLDTALEHF
NGIYLITPFMFYDMTVKLTEYVWQKTREKTG
>A0A0Q4FMJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf16|TrEMBL
MTPTISDLEEARRALDAPLFADLAGDCAVSFEFFPPKTEKMEAALWETVRALEPLAPKFV
SVTYGAGGSTRERTHATVARIARETSMPAAAHLTCVEASRAEIDQVAQEYWTAGVRHIVA
LRGDPPTMGQKFVAHPEGYENAAALVAGLQKLHPFEISVAAYPECHPDSEHQAADLDNLK
RKIDAGATRAITQFFFTPEAFFRFRDAAAAAGIHADLVPGILPVSNVAQVRKFAGLCGAS
IPAWMDRLFEGLDDHPGARALVAATVAAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPKAKPVAVAA
>A0A096AIB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oligella urethralis DNF00040|TrEMBL
MNRIETEGSRFFSLEYFPPREQSARERLVETTKQLLEIDPAYISVTYGAGGSTREGTEDT
VQMVSNLGCEAVPHLACVGSQPEAIREILDSYQAKGIRRIVALRGDMPSGMGLADSPLRN
AVDLVRLIREHSGDWFSIKVAAYPEMHPQAESFDEDLDHFVAKVNAGANMAITQYFYNAD
AYWDFVDRAQAKGVTIPIVAGIMPITNYSKLARFSKMCGAEIPRWIAKRLESYGDDVQSI
RDFGHEVVSRLCDDLRRGGAPGIHFYTLNQAEPVLKICRALQAQ
>A0A4Q2JK02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agromyces fucosus|TrEMBL
MASTATDGSSRGSSPRARAVASTATDASGADCTPRLPVSFELFPPRTDAAALALGRTIDR
LAEVDPAFISVTFGAGGSSRARSLTVLRYMLEHTHVEPMAHLTCVGSSHLEANRLVREFL
DAGITSFLALRGDPPADADPDAGIGDLGSAAELVQLIHRVQEEREPFAQVGVPGNPGASR
IRARPRPERVAVAAFPTGHPRSRNLGHDVDTLLAKEIAGANLAITQLFWRADDYLGFVER
ARAGGVTIPILPGIMPVTTPSRLARLTELTGVEPPASLSIDLEIEPDAAGQTELGIAFAT
RLAAEVIAGGAPGLHLYTFNRHEAVLDVVDRLGLRTDRFADERNTAR
>A0A0N0TCW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NRRL WC-3723|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPKLSNAHV
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>R6MQ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:170|TrEMBL
MSMLKEAFEAGKFGVTAEMAPPKGYDFSEQLEAAKLLNGKVHGVNVTDMQSASLKASSLG
LCVALKNAGIEPILQMTGRDRNRMAIMGDILSAAAFGIDTMLALTGDHPVVGDCPESKPV
YDLDSVGILKMLTKMEETNCDCGGNEIAGGAPKFYKGASVTPVYDPIELQINKLRQKVEA
GAMYIQTQGIFDLDTFKRFLEKVDAAGIKTHIMAGIIPLKAAGMARYMNENVPGIAVPQD
MIDKLAAAAAEGKEKGVKGLPMQLGIEMAAEMIAKIKDEHLCDGVHIMAIGAEKNVPAIL
EKAGVTI
>A0A0A6VS37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria polaris|TrEMBL
MTPRPTARPAPPSLSYELYPPRSAASADTLLRTIEELEPTRPDHVSVTYSGDEQRRDSSL
ALLDHLLARTSLRPLAHLTCVGSTRAELEQTVAALVRRGVRGVLALRGDLDPGAEPGELR
HAGELVELVREVEQRHTAALAAGRLAVGVAAYPTRHPESPSFRHDVEVLLAKQRSGADFA
ITQVYFRPQRYERLVAAARAAGVTIPIVPGIMPVTDPRRLRTLCRLAGLAPHPGLAAALE
DAPGPAERHRAGVAFAARLARAALDAGAPGLHLYTFNEHRAALDLLEHVDLPRVPHVPVA
LEDLLLPA
>A0A752RPH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Carrau|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A5J1TJ36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Meleagridis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8C0NQM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Canis lupus familiaris|TrEMBL
MDQPPPGVLPATVRCSRLGLWTLEAGRVGFSVPPSISRSPAMVKEPRGDGDGGPTPRSEG
SSSGSESSKDSSRCSTPGLDPERHERLREKMRRRMESGDRWFSLEFFPPRTAEGAVNLIS
RFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQI
TGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYP
KGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFP
IQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGL
HFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRT
QEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARY
LSGEPNQHGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIV
GWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNA
VTWGIFPGREIIQPTVVDPVSFMFWKDEEPRGPRQLSRCLVPASTFPATALCSKATPAPV
WPAGPSEDPGTTRGLQFSGHT
>A0A8J2SLS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagomonas calceolata|TrEMBL
MPKICDLIAEKAKAGEDWVSYEFFPPRTEQGVKNLVARFERMKNARQPLFCDMTWGAGGS
TSELTMDLTLKMKAMGLEPNMHLTCTNVERKDVIKALQTCKDNDVRNIVALRGDPPHGQE
KWEATEGGFECALDLVKFIRREHGDYFCLSVAGYPEGHPDTIVHVGDDETKLSASERTRC
RVTDEDGQRKVYVCPDATFKLEMDYLKKKVDAGADAIITQMFFDANTYGAFLKACRKHGI
NVPVIPGIMLVQAAGGFRKMTAMCKTRVPAAVKESVDAKADNDVALKAYGVDLGVQISHE
LLAVGAPGLHFYTLNLDKTTLAIAKRVADDRASSRTARDWLKAAALAAGAAVLVALLRRK
>A0A0M3A0Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. Ag2|TrEMBL
MSKLSQYFAQNQFCCLVEYLPTKNQVLPVRESLAGFPACMTLSDRVRSDEDIAPLIAAQA
YPDHIEKVLHYAGKGRDIDDFKLFLKQADSVGLRDILLLTGDKLKQHHDGQGQHARTRYL
ESVNAVMAAHQYGGFHIGVAFNPFKYTPAEQQAQYLKLHKKLNAGADYIITQLGFDLSAL
KQLQTFLAQEKYIQKTLACVMPLTLARAQFMVKHKVAGIVITPHMLEVLTQDQVNQCPEN
VYKRCALQILICQHLGYAGVHLSACHKADEQMLLEQYIEQYRGLNLSQCEILWNQLWQLA
EGEQLRPKVTAKRIKSALNNKVKYQFLDLIHRAMFQSSFMKGVGTFIFNASFWNRKTAAK
VLLQTEYLSKHYLLGCESCGQCRLAETLYICPETCPKGLANGPCGGTDLDRCEFGDRECI
HSVKSRLAHDVDQIQLLKEQLIPTVPIEVRGTSSWKNWYKAE
>A0A447PRJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MEQTLWNSIDRLSSLKPKFVSVTYGANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATR
DELRTIARDYWNNGIRHIVALRGDLPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVH
PEAKSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSN
FKQAKKFADMTNVRIPSWMSLMFEGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYT
LNRAEMSYAICHTLGVRPGL
>A0A0M3A0Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. Ag2|TrEMBL
MSKRIPISFEFFPTKTDAGAEKLKIVHQELQQFNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHTGDHFKIEVAAYPEMHPQAESYDADIQHFIEKVNAGANAAITQFFFNPDAYFYFV
DRIQKAGIDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDSASIKAFGHE
VVIKLCERLIAGGAPSLHFYTMNHTEPNRQLVLDLGLA
>A0A1M4NB00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. N3C|TrEMBL
MLIKDIFNQKKPVISFEIFPPKKDSNIDVIYNTLEALKDLRPDFISVTYGAGGSTRDKTV
EIASIVKNKYNIEALAHLTCIGLDNAGLNKIIGELVENNVKNVMALRGDLPEGMDKRVLE
ESSFSHASDIITVIKKIGDFCTGGACYPEVHPECDTLDRDIENLKFKVDCGADFLVTQLF
FDNEKFYNFIDKARKAGINIPISAGIMPVTNKKQIERMVSLSNATLPVKFTRIMDKYEHN
PEALKEAGIAYATDQIIDLLSWGIDGIHLYTMNRPETCRKIISNITTIRDTLEGK
>A0A1B8FPZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. 03VT05|TrEMBL
MHIKDMLNQGEQAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHA
QLTCEMVSVAQSVYGLETCMHLTCTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEK
WVATDEGFQYARDLVKYIRKTYGNHFDIGVAGYPEGCDDQTDADLLLGHLKEKVDEGATF
IVTQMFYDVPNFLDWVRKVRAKGITIPIIPGIMPISTYASFLRRCNHMNAKIPPGWIEAM
EPVKNDDAAVREIGRGLVTDMCRSILESGINHLHFYTMNLAQATRGVLEQLEMLPSEERP
LKQALPWRQSLGLGRRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGEPKSVKDIANVFLRYLSADIESLPWSEAPISNEADVIKNQLVE
LNERGLLTINSQPAVDGVKSSHPVYGWGPLNGYVYQKAYLELLVAPELIDKLLDRIARDP
EVTYYAVTKSGTLRTNAPSDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHDASSPSRNVIQRVMETFYLVNIVHNDFHQRDALFSLFEGLTVPNIDKAAEGTTAPA
AAPAPAAAAAPATNGDKVKDAAPAIVSNVLPVA
>A0A2S5AIY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Avibacterium endocarditidis|TrEMBL
MSYAKEIDTLNNHLSGINGNINVSFEFFPPKNENMEKILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKHIKQETGLEAAPHLTGIDATPEELKKIAQDYWDSGIRRIVALRGDEP
AGYDKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAEITNVKIPAWMAKMYEGL
ENDQTTRNLVAASIAMDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGVRPE
>A0A2M9K0G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB01635|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTFSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAQLRNIIGQYADAGIRNILAVR
GDPPGDPMADWVAHPEGLTYAAELVRLIKESGDFCVGVAAFPAMHPRSEDWDSDVRHFVD
KCRAGADYAITQMFFYPEEYLRLRDRVEAAGCDTPVIPEIMPVTSVRMLERLPQLSNATF
PPALKERILTAKDDPAAVRSIGIEFATEFCAKLLDEGVPGLHFITLNNSTATLEIYENLG
LHDQRA
>A0A416MD67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF25-23LB|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EHFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A537SVJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MNNDPLRLTGAPPRGLLAADPVSDFDAGPPRISFEFFPPKTPDMDERLWAAIKRLEPLRP
RFVSVTYGAGGSTRERTHATVRRIRQETVLEPAAHLTCVAATREEIDSVIRNYCTVGVRH
IVALRGDPLGGLGDRYAPHPGGYCNAADLVAGIKRLSDVEVSVSAYPEKHPDSSTVEADL
DMLGAKVDAGATRAITQFFFENDLYFRYLDRVRARGIDVPVVPGILPVQNFKQTKAFAAR
CGASVPDWLAERFDGLEDDAATRKLIAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAV
CHLLGLRPSQETDALPLPIVEKERA
>A0A1G6LER4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces prasinopilosus|TrEMBL
MSTVREALASGVPSFSFEFFPPRTAQGEQALWRAVRRVEPLCPTFVSVTYGAGGSSRERT
VEVTRRIAAETTLRPVAHLTAVGHSVAELRHIVGQYADAGIRDVLVLRGDPPGDPNGPWI
PHPDGFTHARELVELVCSLGDFTVGVAAFPEMHPRSPDWDSDIRHFVAKCRAGADYAITQ
MFFDVEDYLRLRDRVTAAGCDIPIIPEIMPATDVRQIRRFAELSHAAFPEDLAHRLEAAR
DDAALGHRIGVEHATVMAERLLAEGAPGLHYITLNKSPASLDIHHNVLAAARPGQAEHTG
TPSTPG
>A0A2E8XT77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSATSVSFEFFPPKTAEMEQTLWETVCDLASIDPAFVSVTYGAGGSTRERTHATVTRIVK
EAGLTVAAHLTCVAATRADIDSVARDYWNAGVRHVVALRGDPPEGEVVYTPHPDGYAYAA
DLVEGLRQVADFEISVAAYPEVHPEAPGADFDLDNLKRKVYAGANRAITQFFFDNDVFLR
FRDRAVAAGIDVPLVPGIMPVGNFKSMTRFAEMCGASVPDHFEAAFAGLDDDPAGRAEVA
ERLASEQCLDLQSRGVTDFHFYTLNRAELTHAICRNLGIGDVSRERIEG
>A0A4S0G2Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1C.F.Ca.ET.192.01.1.1|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPEAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLRGRQPWQREIRRDDQIVAERLDHILHDEITETQVDMVK
TAH
>A0A3M2HIT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp|TrEMBL
FGPAARRLVAEMTYEVVPMAGVDAAIEALPAGSPVSVTCSPVKGIDATRELTERLLAAGH
RPVPHLAARMVASRDETRRLAAWARQVGLHALFVVAGDAPEPAGPYEGAVPFLADLIEAG
PGVAAVGVTAYPDGHALIDEAELVRALHAKQALLTEAGVEAWASTQMCFDTGRIRSWLED
ERRRGLTLDIHLGMAGVVDRAKLMTMGVRLGIGASLRYLRKNRASVTRMLAPGGYDPSHL
VVDLAPDADRLGITGLHVFTFNNVAATRHWQEAVTSGEDAP
>A0A258YUP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuricurvum sp. 24-42-5|TrEMBL
MFESFIHKLRHGTFITLETTPSRSSQFAPTIEKIAAFGLDNLVDGFSTTDNPLAKLKYNA
LFAAMKLQDRFGKPTLATMSMRDRNRIALQSDLLGANESDIRAILALTGDSAHYSDQPHT
KGVFEGNSNLLLDIITTLNSGTDLAEQKLMAPVQEIYPFAVIDSYSKNANALQKKMVKKV
AHGAIGLVTQPVYDTTIAQQLLTMMEHSNIQNPERENCVLILGFFPITKLRTARFLDENV
PGIHVPHEWVDALEQASLISIEEEYKVGFELSKNLFEELKSLHPKIHIMTANQFELAKAI
LN
>A0A4R9JPY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira kemamanensis|TrEMBL
MHISQVLQKKQTTISFEFFPPKNEEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEQTGLTIVSHLTCVGSTKDEIREILKRYEKSGIHNIMALRGDPPKGQNEFQKT
ENGFGFAGELVGFIKKEFPTMGIGVAGFPEGHPSTPNRLKEIEFLKWKVDQGADYICTQM
FFDNNSFYDYVERCEIAGIKVPIIAGIMPITSRKGLARMAELSLGTNFPAKLLKSLSRAE
DDSYAENVGIHWATEQVRDLLDHKIAGIHMYTLNKSKATRRIYESLGIRNFDTIV
>A0A1M6GS26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesonia phycicola|TrEMBL
MKVVDHIKKAEGKTLFSFEILPPLKGQNIQSIFDHIDPLMEFQPPFIDVTYHREEYVYKE
LLNGLLQKKVVRKRPGTVGICAAIQNKYQVDAVPHILCGGFTKEDTENFLIDLDFLGIDN
VLALRGDAVKNETYFSAEKEGHSYAKGLVEQIVGLNKGEYLDEELLNKSKTNFCIGVAGY
PEKHMEAPSLDQDVLRLKEKVDAGACYVVTQMFFDNKKYFQFVEKCRNAGITVPIIPGLK
PLATKRQLSVLPHRFHVDLPDALILEVLKCKSKDEVRQVGVEWCIQQSKELIANGVPFLH
YYSMGKSDNIEKIARSLF
>A0A539DB57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MTAVQKTQPVQAVFDAAAARLGRVGGPRVSFEFFPPKSDKLEEQLWAVIRRLEPLAPSFV
SVTYGAGGSTRDRTHRTVSRIVEETSLTPAAHLTCVAASRGEVDDVMRAYWDAGVRHIVA
LRGDPQGGAGAAYEPHPDGYAYAADLVAGARKIAPFEVSVAVYADKHPDSATWQTEIDNF
KRKIDAGATRGISNFFVDADSFLRLRDRLADAGITAPIVPGVMPVSNFNGFKRMAAVGGV
YVPDWFAAIFEGLDDDPETRLLVAAATTGELCARLAAEGVEDFHFYTLNRAELTLAICRM
LGVKAQKEVAQ
>A0A1E3YZV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella sp. SCN 67-23|TrEMBL
MSSSLSPDAAPADAAPVFSLEFFPPRDIAAQERLVRTAKQLQGLHPHFASVTFGAGGSTR
DGTMLAVSMLQKLGYEAAPHLSCIGSTPESLRDILYTYRQAGIRRLVALRGDMPSGMGDM
GELRYARDLVDFIRKETGDWFHIEVAAYPEMHPQAQGPEADLDRFVEKMRAGADSAITQY
FFNADAYFDFVDRATAKGVLAPIVPGIMPITNYTQLARFSDMCGAEIPRWIRLRLASYGD
DRASIRAFGHEVVVELCQTLLDGGAPGLHFYTMNQADATQAVWKELER
>A0A5Q4FCC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneolaceae bacterium|TrEMBL
MKVTEHYDKAKDPLISFEIIPPKRGGSVSRVFETLDGLHKYHPPFIDVTSHAAEAYYEEL
ADGAVKRHIRRKRPGTIGLCAAIKHRYNVDPVPHLICKGFTKEETEDALIELNYLGIDNV
LAIRGDDHGYQKPVRKDRGINEFAVDLVRQIKRMNSGVYLEELMDAEQTDFCIGVGGYPE
KHIQAPNLSFDIARLKEKVDAGADYIVTQMFFDNESFFRFVEKCRDAGILVPIVPGLKIL
TMPRHLTTLPQAFHLSIPEALTAEVSARPEYALDIGVEWAVKQCRELLEYGVPGLHFYVM
GNPDPAIRVIDQLDVIPATSS
>A0A1S7NT25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium tomkonis CFBP 6623|TrEMBL
MLRSETARHDGDIRLSFEFFPPKNAEMETHLWETVAELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIGTAYR
PHPEGYENAAALVKGLREIGDFEVSVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVNAVLENLGLERLRRSAA
>A0A537N6Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSLSEFPVRAAQRLQVSFEFSPPKTEAAERTLWETIERLAPLKPTFFSVTYG
>A0A6I4N789|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. BA2|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKETQQIVADSTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPLADWVKHPEGLTYAAELVQLIKESGDFCVGVAAFPAMHPRSEEWDTDVRHFVD
KCRAGADYAITQMFFYPEEYLRLRDRVEAAGCSTPIIPEIMPVTNVRMLERLPQLSNASF
PPALKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPQA
>A0A6I2MPN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter luteus|TrEMBL
MKVTDHIKNAKGETLFSFELIPPVKGRNIQELYNNIDPLIEFKPPFIDVTTSREEYIYID
RDGLLDKKLTRMRPGTVGICASIKHKYQVDTVPHILCGGFTKEETEYVLIDCHYLGIENV
MALRGDARREQKYFEPTKGGHAYALNLVEQINDLNKGKYLHEMIENDDNADFCIGVAGYP
EKHLEAPSLQSDLKRLKQKVDAGADYVVTQMFFDNQKYFQFVEAARNMGITVPIIPGIKP
IAVKRHLQLLPQVFRIDLPQDLIDAVDGCADNKAVRQVGVEWAIQQSKELKAAGVPVLHY
YSMGKSDNIHAIAKEVF
>A0A534MH27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MVSPRRALFSVSDKEGLVEFARGLRAVGFELIGTEGTAKTLKDAGLPVMTVADYTGLHEG
LGGRVKTLHPKIFAGILAPRIPLKSAKMARFMVEKLGAVVPKHILDRMDRAPNPKAEGVS
IAVRTIKALKKIEGVRGVHIMPIGWEEIVPDLVREAGLLPRPDPTP
>A0A5A9XGZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzomonas rubra|TrEMBL
MTLLDKLTTEILTGDGAVGTMLYARGIGLDSNFEHLNLVRPALVLELAREYAAAGAQVIE
TNTFGANYTKLAAIGLGHKVGEINRAGARIAREAAGNGGILVAGSVGPLVRMKGEEQELT
PDAMAGHFRAQCTALAEGGVDLLLLETFGSLEQLVAAVRAARETGLPVCASMAFLEGGRS
GDGTTVEAFCAAVEAAGADMLGANCGAGPLELVKVVRRLAALTAKPISAYANSGFPEYHE
GRYIYRATPDYFAAMADEMAAAGANLIGGCCGTTPDHIAALARTLAGKRPAPRYPAPSRA
AAGAQHGFRPDKPSFLDPWGRRKVITVELDPPKGMDCRRIIESSRRLKEAGVDAINLAEN
PLARPRMGNIALGSTIQREVGVEVIIHITGRDRNLIGMQSDLMGASLLGLHTILAVTGDP
AAMGDHAGATSVFDLHSFTLIKLLSDMNRGVNAIGNPIGSGTGFTIGAAFNPNTKNMAVQ
AERLRKKVANGARFAQTQPVYDPALFLEALEQTRDCGIPLLPGIMPLVSERNAEYLHNEV
PGITVPDAIRARMKGLEKEAGAREGLAIAKEFIDATFTAAGGYYLIPPFGKCELALELID
YIHAREREQR
>A0A850TL95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grus americana|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLR
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A534LLG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MAEAVGVRAVRSGGHLERMLASGAFAVTAEIAPPASADPTDIREMVSRYRGAVDACNVTD
CTRARVRLSSLAAATIAMQEGIEPVMQIVARDRNRIALQADLLGAAALGIRNVLCLWGDP
VSAGNEPEAKGVFDLKTEEMIETFRDLRDRGRLRGGDAVDAPPKVFIGAAADPFRGSKEE
SFAKLRAKVLAGADFVQTQAVYDIDAFEEWMRLVRKEWLHEKAYILAGVIPLRSVKMARF
MVEKLGATVPKHIMDRMEKAPDPKAEGVSIAVRTVKALRKIDGIRGVHLMPVGRDGVVAK
VVKESGLLPRPEPSL
>A0A1E4R161|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus fusiformis|TrEMBL
MGLLERLKTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESSVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLDDI
LATVEEQASVLLAGNPDGLLLETYYDFEELTATLKMLRTKTNIPIIAQVSMHEPGVLQNG
MSLNHALHELEILGADIVGVNCRLGPYHTIQAFEGVELPEKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVSEKHAKPAKIEI
VRDAEPAKFEPLHEKVKRERSVIVELDTPRHLEIEGFLEGAKQLYEAGADVVMMADNSLA
SPRISNIAMGALLKSTNGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDVLAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKIIEIYEATKHLQAPIYLGIMPVTSYKSAEFLHHEVPGI
KLSEDALSRMKACGEDKERATLEGIAIAKELVEVAAQYFNGIYLITPFLRYDVTLELMKY
IEQLDEQKKGVSING
>D4Z568|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium japonicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S)|TrEMBL
MTLGFPSVEAAQAWQAPLYADLAGDVNVSFEFFPPKSEKMEEQLWSAIQTLTPLAPKFVS
VTYGAGGSTRERTHNTVARIAKETPLSAAAHLTCVAASRAEIDEVADAYWEAGVRHIVAL
RGDPPEMGAKFEPHPDGYKGAAELVEGLRKRHPFEISVAAYPETHPDAQSAQSDIDNLKR
KLDAGATRAITQFFFEPDTFFRFRDTAAAAGIDADIIPGIMPVSNFAAVQRMSAMCNTDV
PGWMGKLFEGLDDHAAARQLVSATLAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVATNAV
>A0A4R3M6U1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidamorphus gemmatus|TrEMBL
MSHNSVLPKARCRMAASIEATPRQVLETDHLEGLFPPQTRVYLTDVGTTTPADLIAAARR
LRLAGYTPVPHVAARRIMSHAELADRLSRLTGEAGVDDLLVIAGSVETPAGPFASSMDLL
RTGILARHGITRIGVAGHPEGSPDIPTDEVAAALAWKAAHAAQHGIEMRIVTQFGFDAER
YVAWADGLRAAGITLPVHVGVSGPARITTLLKYAALCGVGPSLDFLKKRAGSVMALAAGY
SPEGLVQSIEAHVSAHPDCAITQIHVFPFGGLRKSAEWLAERGSWFSEAVAIDDTGHWLE
A
>A0A2Z4IY08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces cadmiisoli|TrEMBL
MTTFSFEFFPPRTDAGERTLWEAVRRVEALCPDFVSVTYGAGGSSRDRTVAVTRRIAAET
TLRPVAHLTAVGHSVAELRHTVGRYADAGIRDVLVLRGDPPGDPGGPWTPHPDGFTYACE
LVELVRSLGDFTIGVAAFPERHPRSPDWESDIRHFVAKCRAGADYAITQMFFHVEDYLRL
RDRVAAAGCAIPIIPEIMPATDVRQIRRFAELSGAAFPEDLAHRLQQARDDPDTAHRVGV
EHGTAMAERLLAEGAPGLHYITLNRSSAALDIHRNVRAAAGPSRVPSTSGMA
>A0A417F1H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyricicoccus sp. AM32-19|TrEMBL
MKVSQLLNQDKVTLSFEVFPPKTSSSYESVAHATQEIAALRPDFMSVTYGAGGGTSEHTV
NIAADLKKKYDVTVLTHLTCVSSTREHVAAMVKKYKDAGIENILALRGDIPEGGAPHSDY
HYAAELVRDIKSQGDFCVGGACYPEGHVEAANKTEDILHLKEKVDAGCEFLTTQMFFDNN
IMYNFLYRIREKGITVPVVAGIMPVTNVKQIKRITSMSGTYLPERFKAIVDRFGDNPAAM
KQAGVIYATEQIIDLIANGVNHIHVYSMNKPEIAAGIQSSLSEILK
>A0A1L8MY05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp. CETP13|TrEMBL
MKIAQMFENRTLFSFEVFPPKRTSSVDTILTTLDGLKGLKPDFISVTYGAGGSVVNNETV
RIANLIQNQYGIETLAHLTCVESSKNDVDAILSQLQDSGVENVLALRGDLKPNEQPKDDF
KYASDLVSYIINKTKNRSNGSFDVCGACYPEVHGEAKDSVDDILNLKKKVDAGATHLISQ
LFFDNQKFYDFKERARIAGVNVPIEAGIMPVVKKSQIERMVLMCGASLPSKFVKTMQRFE
HNSQALRDAGIAYAVDQIVDLVSNGVEGIHLYTMNNPYVACKISEAVENIVRCK
>A0A0U5IGZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiocapsa sp. KS1|TrEMBL
MPLQSHQTPTYSVELFPPKTPEGMDKLKTEIARLNSVLPSYFSVTYGAGGSTRDRTFETV
DWLRGHDIETAPHIACVGSARAEIREILGRYREQGIRRLVALRGDLPSGMGGGTGGDFRY
ANELVTFIRDEFGDSFKIEVAAYPEYHPQSGSPERDLANFKRKVEAGADAAITQYFYNPD
AYFAFVESCKRAGVTLPVVPGIMPITNYTQLARFSDACGAEIPRWVRRRLEGYGDDVESL
RAFGHEVVLNLCRRLIDGGAPGLHFYTMNQSGPTLRLWQDLALPRPA
>A0A434T3X4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M2A.F.Ca.ET.015.02.1.1|TrEMBL
MNQFRFSRRPDIGEKVSVSFEFFPPKTDEMEARLWDTVTRLEPLKPEFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARDQVDTVIREFVDFGVTRFVALRGDPAAGVGT
SYRPHPDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAT
GSAAA
>C0E4L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium matruchotii ATCC 33806|TrEMBL
MTQQPLPEPTPARYQRSITDVISSPAPGRIPFSVEFMPPRNDEAETRLRTAAETFHDLGV
AFVSVTYGAGGSSRDRTMRIAQDLARMPLTTLVHLTLVGHTEAELVEILSDYASLGLSNL
LALRGDPPGADPLGEWTPVPGGYRYAEELILLSKRLEATKHFQVGIAAFPEGHHQSESLA
ADTKYTLAKLRAGAEFSITQMFFDVDYYLRLRDRLASADAELGSRPIIPGIMPITSLKSV
RRQLQLSGAKLPARLEERLVAAAAGDEEANRDEIRKVGIEESTLMAERLIAEGVPDLHFM
TMNFARATQEVLHNLGMAPAWGREHGHDAVR
>A0A562CV96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. J9|TrEMBL
MTTGAGRSLGELIREGGRSFSFEFFPPKDEAGEVQLWDAIRALEPYRPTFVSVTYGAGGS
TRDKTVAITGRIARETSLIPMAHLTCVGHTRGELEAILDAYGREGVNHVMALRGDPQEGP
RAEWTPTDGGLNYAIELVELARSRGDFRVGVAAFPEGHPSAESLDADADVLVAKARAGAE
FAVTQMFFRAEDYFGLVDRVRARGVDIPILPGIMPILNLSAIRRQGELIGTSVPQPVVDR
ISAYDGDPAAVRAEGIRLAAELCDELLVGGAPGLHFYTLNRSKATLEIFEALQITV
>A0A6B3I253|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID8455|TrEMBL
MALGTASTRTDHAPTVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSEDWDTDIRYFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LQDDKG
>R6HCU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phascolarctobacterium sp. CAG:266|TrEMBL
MKITELLKDDKPCISCELFPPKAGSELQNALKIVDKIAEIKPHFMSVTYGAGGTSAGQTV
AIAKAVEEHNIPALAHLTCIDATGNGIESMLGKFRDNGIQNVLALRGDAVTDKPREFMHA
SDLMRKISASGDFCIGGACYPEGHPEAGSLDKDIENTKKKIDAGCEFLVAQMCFDNNIMY
NYMYRLLRNGIDVPVVAGIMPVTNAKQINRICELSGTKLPPHYRAIVERFADDPQALMQA
GIAYALGQIIDLIANGFKNIHVYTMNKPEVIGGIMKNLSEIIK
>A0A418SMD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus onubensis|TrEMBL
MALRTPHVSFEFFPPKTLDASFRLWETARGLAPFAPDFVSVTYGAGGTTRKLTHEAVTTI
KRHYGLEVAAHLTCVEATRDETMKIVQEYADAGIREIVALRGDAPKGQERFTPHLDGFAN
SVELIEAIAARGDMTIRVGAYPEPHPDGSGTDSDVAWLKRKIDAGASSAMTQFFIEPETF
FRFRDKCAAAGIDAPIIPGVLPIQSWKGARRFAEATGTSVPQWIDDAFDKTDGDPAAERE
LATRLCVELCEKLIDGGVERLHFYTLNRPELTRDVCLALGVKPTRALENVA
>A0A5Q4E4S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. DLM2.Bin27|TrEMBL
MFLASAPLGYRLRTAAKAGEFLVTAEVMPPKGGNPDHMLAMGQLLKGRVHAVNITDGSRA
VMRMSSWAAALLLQQRGVEAVCQVACRDRNRIALQADLMGAHALGLRNILALTGDPVKAG
DHAEARAVFDLESVRLLKLLGQLNGGVDSHDKPLPDGALDLFAGAAIDPQSPSWSGLQRR
FEAKVKAGAQFFQSQLITDFDRLAKFMDQVAADYNRPVLAGIFLLKSAKNANFINRNVPG
AHIPQAIVDRLAAASDPLQEGVQIAAEQVRAARQVCQGVHLMAVRREDLIPQILDQGDVA
PVDALAQR
>U2CFH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. KLE 1732|TrEMBL
MIRFIGNIPQCMLQSRWTVPQILNDWSKYNMKMKELFDRGEFVVSAEVGPPKGIHVDELV
EEAKTYLKGVHAVNVTDNQSSVMRLGSLAMCKVLKDAGMDPIFQLACRDRNRIALESDLL
SAAMLGIENILCLTGDHTKMGDHPQAKPVFDLDSVSLLHTVQLLESGVDLGGNQLVGEPP
KFSKGAVVSPCSDSVDAQLAKMERKVAAGADYFQTQAVFEPEKFIKFMEKAKQFGKPVQV
GIIIPKSAGMAKFMNNNVAGIHVPDEMIEELKADKEKTKAGITGVEIAARIIKECKPYCQ
GVHIMALGWESKIPALLEQAEI
>A0A7C3YWZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans|TrEMBL
MTMTAGSNLEKILRAGHKAVTCECGPPRGADVEHFRHKASFLKGYGDAVNVTDNQTAVVR
FCSMAASRILLDMGIEPVMQMVTRDMNRIALQSNVLGAAALGIKNLLCLTGDHQSFGDHP
QAKNVFDLDSTQLLNTVRLMRDEGKMISGTEVEGRPQMFIGAAANPFADPF
>A0A7C3UXW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans|TrEMBL
MKLTELFKQGKFVITSEVGPVKGCARVNGGPPPEFIKEALAIKDYVDAVNVTDNQSAVMR
LGSLAGSLLLKQYGLEPIYQVTCRDRNRIALQSDLMSACTLGIDNLLCLTGDHIKLGDHT
AAKPVFDVDSVTLLRLAKGLNEGHDMVGNPLTRATDLALGAVVNPGFEPMDLQLLKMEKK
IEQGAEFFQTQAIYDPKVFEIFVRRIETFKVPVQLGLVIIKSPKMARFMNEHVSGIRVPE
ALIQEMAAMPAAQYKERAGEIALRMAREMGPMVQGIHFMPMGWSDLVPPIVTELRKIMK
>A0A418NRW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantiacibacter zhengii|TrEMBL
MEVSDSQMAKAGRDSQFAGLPGDISVSFEFYPPATETAEEQLFRAFHRLAPFAPSFVSMT
YGAGGSTQSRSIAGVQRLIAEGEVPVAAHLTCVGASREEVDAVAMQFWDAGVRHIVALRG
DGGKPGEPFVPHPDGYENAADLVAGLRKLADFEISVAAYPEVHPDATSAEADLDNLKRKL
DAGASRALTQFFFSPDAFLRFRDRAAAAGIDAPIAPGILPVTNFAQVCKFAGACGALVPD
WMHAMFEGLDDHPETRKFVATTITADLCRSLYDGGVRDFHFYTLNRAAQLEAVCHLMGRR
LPAARLEAAA
>A0A826ZBX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDAMPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3D8IVD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter equorum|TrEMBL
MIEQFVAKLGTKQRLLTLEVTPPLSPILAGSKEVEKLLTLSSEVAIDAFVCTDSPLAHFK
PSSILSSIKLQNLTHKPVVCTLGMRDRNSIALCGDILAANEFGLRSFLCLTGDPIKLGDC
AESKGVFEENSLKLMRIIHNLNEGKVLNGKALKDSMEPIYGFQVINSYANNPQSLKTKMR
KKISQGKPYALFTQPVYSKEMAECLLQSLDEINAELGTHTTLIFGFFPVVNYKVAIFLRD
KLPGVFIPDTWITQLQNAKDNEYEVGLELSRELLTQLRSLHDKIHFMSANKLELVREFYL
S
>A0A376TZW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPRVPVKWSRPCGTPSIA
>A0A2X1KDQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MPWNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTYGANSGERDR
THSIIKGIKDRTGLEAAPHLTCIDATPDELHTIARDYWNNGIRHIVALRGDLPPGSGKPE
MYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGAKPRDYSVLLRCR
KLPAFS
>A0A162QFU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavihumibacter sp. CACIAM 22H1|TrEMBL
MKVIDHINQAKDTLISFEILPPLKGKGISAIYNHLDPLMEFKPAFINVTYHRSETMFKKQ
ADGTFNKIEVRKRPGTVGICAAIMQHYNVDPVPHLICGGFTKEETENALIDLAFLGIDNV
LVLRGDAAKNETFFEPEPGGNRYAIDLLKQVMDLNHGIYLEEEVKDPGKATFCIGVAGYP
EKHFEAPNKATDIAYLKAKVDAGAEYVVTQMFFDNQKYFEFVQNCRMAGIQVPIIPGLKP
ITNKKQMTILPRIFNVDLPDQLATEIMKCKTDVEVEQVGTAWLLQQSRELKKAGVPVLHY
YTLGKPKVIWNVVKELV
>A0A0Q6K2I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf339|TrEMBL
MTISVNQLAEARRALESPLYADVGGDLAVSFEFFPPKNEKMDIQLWESVRTLEPLGPRFV
SVTYGAGGTTRERTHATVARIQRETSLAAAAHLTCVEATREEIDQVAEEYWAAGVRHIVA
LRGDPPQQGACFASHPGGYENAADLVAGLKRLHPFEISVAAYPESHPDSPDAAADLDNLK
RKLDAGATRAITQFFFEPETFFRYRDQVAKAGIDAEIVPGIMPVSNFASVKRMSAMCGTA
VPPWMGRLFEGLDEHPASRQLVAATVAAELSRRLYAGGVDQLHFYTLNRAELAFAICHLL
GVRAKASSEAAAA
>F9RKH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio scophthalmi LMG 19158|TrEMBL
MGYTHASHIDALNQNVAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKNLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLIAAPHLTCIDASRQELVQIADDYWANGIESIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFNQASRFAAQNHVKVPGWMAKQFE
GLDDDPTTRQLVGASQALDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A2Z3HSH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phenylobacterium parvum|TrEMBL
MTEPALGPIARAGAGLAQPPRVSFEFSPPKTEEAEVALWEAIRRLAPLNPAFVSVTYGAG
GSTRDRTHRTVSRILAETQLAPAAHLTCVDASRAEVDDVIRDYWDAGVRHIVALRGDPPG
QIGGVYVPRPDGYVNATELTAGIRAIGPFEVSVSLYPQTHPESGSVDHDIDVLKAKIDAG
ATRAITQFFYDTDGFLRFMDRVRKAGVTIPISPGIMPVSNFKGLKRMAGPVGIPLPGWLG
ALFEGLDKDPETRRMIAAGVAAEMCVKLAEEGYSDFHFYTLNRADLVYAICRILGLRETA
E
>A0A315CS51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. Hippo4|TrEMBL
MKKLPVSFEFFPPKTPEGAEKLRVVRQQLYTQAPEFCSVTYGAGGSTQEGTFGTVGEILK
EGVAAASHFSCIGASEESVRKELATLKAMGVKRLVALRGDLPSGYGMGGAFHYASDLVAF
IRKETGDDFHIEVAAYPEIHPQAKSAESDLQAFVAKVKAGANSAITQYFYNSDAYFRFVD
DAHKLGVDVPVVPGIMPITSSTQLLRFSDACGAEIPRWIRLRLQGFGDDTASIKAFGLDV
VADLCDQLRNAGVPALHFYTMNQSATTLELLKRLA
>A0A1C3RKC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Terasakiella magnetica|TrEMBL
MTIKEEQKAILSGLPVAAPLPNDVNVSFEFFPPKSEKMEETLWASLKRLEPLGPQFVSVT
YGAGGTTRERTHNTVVGIQKETSMTAAAHLTCVGSSKAEIDEIADRYWEEGIRHIVALRG
DPAEGDKTYTPHPDGYAYAVDLVEGLKKRHDFEISVAGYPENHPEAPSEQFDLDYLKRKV
DAGANRVITQYFFEAETFLRYRDKAAAAGVTVPIIPGILPVTNFKQVLKMSDMCATNVPA
WMADLFSGLDEEPETRKLVAATVASELCRVLHANGVKDFHFYTLNRADLTYAFCHVLGVR
PKGTK
>A0A376TZ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MELHRSLSSLKPKFVSVTYGANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRT
IARDYWNNGIRHIVALRGDLPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKS
AQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAK
KFADMTNVRIPAWMAQMFDGLDDDAETRKLVERILPWIW
>A0A433J8Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum doebereinerae|TrEMBL
MTAPISATPSVSFEFFPPKTEKMEQSLWQSIRRLAPLAPSFVSVTYGAGGSTRERTHATV
CRIQAEAGIPAAAHFTCVGATRDEIDSIARTYWDAGIRHLVALRGDPPETAGGVGGTYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDAYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPAKLASTFEDLDA
DPETRQLVAATVAAEQCQALQAQGIKDFHFYTLNRSDLTIAICRMLGVKAKAAPAAAPAP
VAG
>A0A431UTC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus telephonicus|TrEMBL
MRLLEALKSKVLTADGAMGTLLYSYGLDNCHEEMNLVKPDVIEKIHREYIAAGADVIQTN
TYGANAIKLARYGLESKVVEINAAAIAIAKNAVSNGNQFIVGSIGGIRGVRKSDSTLEEI
LASVRVQAEVLINGGLDGLLLETYYDFEELSETIKMLRIITDIPIIAQVSMHEPGVLQNG
LRLNAALNELESIGADVVGVNCRLGPYHTIQAFEGVELPENAYLSAYPNASLLDIEDGRV
IYESEVDYFARASVQLRNQGVRLIGGCCGTTPKHIESVKKKLEKLKPVESKETKLQQEIF
IQDPEPRKLEPLHEKAKRERSIIVELDTPRHLEIDPFVEGAKALYDEGADIIMMADNSLA
SPRISNIAMGSILKLQHGIRTMPHITCRDRNLIGLQSHLMGLNALGLHDILAVTGDPTKV
GDFPGATSVYDVSSMELISLIKQLNEGISFSGKTLRKKANFSVAAAFNPNVRVIDRAVSR
LEKKIEHGADYFISQPVYSKEKIVEIYEATKHIEAPIYIGIMPLTSFRSAEFLHHEVPGI
KLSDEVLERMKACEGDKIREAQEGVAIAKELLDTAVQHFNGIYLITPFLRYDLTIQLMQY
IKQLDEQNKGVKVNV
>A0A348AG84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomusa anaerophila|TrEMBL
MTAKLSLQAALADPAQLSVTWELVPGQGAREKAQEHLVKMAELAAKDAKINAVTITDNPG
GKSAIAVYAMAVEAKRLGIDPLVHFTGKDKNRNALESELYALERAGIENLLVMTGDYPVS
GYSGNAKPVFDFDAVHVLRLIGKMNDSTYTKLAPTHFFAGAVVSPFKSTEAETMAQYYKL
HKKVANGSRFIITQLGYDARKFDELKKYVMLNNLAVPLIGNIFVLSLPVARMMNKNLIPG
CVVTDSLVARLEEEAAHSNKRELQLLRAARQYAVLKGLQYDGVNIGGHGLSYQDVQFIME
KGEELSSNWQDIAAAEFNHPQAGGFYFFEEDAATGLNTCQPADRRRTGPGRTSLKQSLMN
MVHGVAFDQQSPLYPANRAAARYIDKSWLKQPFTGAEYITKTITNECRFCGDCAMHELGF
ICPMSQCPKQQRNGACGGSRDGWCEVYPGKQKCIYVKMYEEFKGRGREDRMKEKYMPPCN
WDLHRTSSWLNYFNGRDYNNNKD
>A0A6J4XFW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius sp. associated proteobacterium Delta 1|TrEMBL
MSVNTASKLEKILSEGHYAVTSECGPPRGSKPEPILEKAELIKDHVDVINITDNQTSMTR
LCSLAACIRLKLNGLEPVLQMVTRDRNRIALQSDILGAASFDINNILCLSGDHQSFGDNP
NGQNVHDIDSMQLIQMVRLMRDEAKFLGGDDLDRPVKMFVGAAANPFADPFEIRVPRLAK
KIAAGVEFIQTQCIYNLDKFEEWMKGVRERGLHEKCYILAGLTPMKSVGMAKYMQKRVPG
MDVPDEVIKRLQGVEKGKQAAEGIKICIESIERLKECEGVKGFHIMAIEWEEKVPEIVEA
AGLYPRPSVN
>A0A640W7W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinicola corii|TrEMBL
MSTQPPLGFSFEFFPPNTDAGREKLGGVRDALAARKPRFFSVTYGAGGSTQARTFDTVRT
VRRSGVTTAPHLSCVGSDKSALRDLLHAYREDGVDSLVALRGDLPSGMGGAGELRYANEL
VEFIRDETGDHFEIAVAAYPEAHPQAPSFERDLENFARKARAGANIAITQYFFTAEAYFH
FVERVRAMGIDTPIVPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDSDSIQAFG
TEVVSNLCRRLLDGGAPGLHFYTLNQSAPTLRVLDNLN
>A0A7C0XBR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotogales bacterium|TrEMBL
MILFKSPGNFLERELLEYPGWSVNSENPPKAHENQKNDQNGENQPAPPHIQPSHKLRSAN
RRDQKILYIIEDKIQISQSCDKMGFALVHKATQAYDRIPLNTKEGVEIVGRLKEDIENKR
AFIVEVLTPRGTDISKTIELAMNLKRIGINVVSITDTPLGRARMSPWAVSHNLVEMGLDV
LMHFTRISRNLLRIHADLLGIHALGIRNLLVLSGDDPKEGDYPESTVLNDITTEDLIRLI
RSMNLGYDLKGRRIKPNTDFLIGAVFNPFIEREIDRAKKKLENGADFLISQPVFKLDDLP
EFHLDSSKIVISLVLFRNKKHFRLFAGVPGVRMKDGFIENMEKLDDDGVRMRSIESASEI
VRKLRNEFAGFYIIGVTTSSWKMVGELLLKV
>A0A6H5JB66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectocarpus sp. CCAP 1310/34|TrEMBL
MPSEPDTKIIKLIQASAKEALTEGGAGFQSLEFFPPRTDTGVKNLMERLGRMKATKPLFV
DFTWGAGGSTAELTLDLTTRTKKEHGLVPNMHLTCTNMPVDKIDHALAQCKEHGIRNIVA
LRGDPPTGSDTWEATEGGFSCALDLVKYIRKNHGDYFGISVAGYPEGHPNRIKEVPGGVE
SLSEAEKGRCKISQDAEGKEVVTVCSDADFEIEMSYIKEKVDAGADFIITQMFFDPAVYA
SYIKACRDRGIEVPVVPGLMCINAYGGFKKMTGFCLTRVPPELMAKMEEIKEDEKAVKAF
GVDHGEEMCKALLAAGAPGLHFYTLNLEKVTVGILDRLNLLADYKMAEREEDTAQMIGMI
KSSKKSSEESGPENGAGVTPPAPSSLVQTHDEERVLTPA
>A0A2N2Q1K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-8|TrEMBL
MSDPVISFEFFPPKTAEGVAKLRETRKQLAQLKPKFFSVTFGAGGSTRDRTMDTVLEIQN
EGYEAAPHISCISSSKQEIFDLLQAYKAQNIRHLVALRGDLPSGEASAGDFRYANELVAY
IREQTGDWFEIEVAAYPEFHPEASSASADLKNFKAKVDAGADAAITQYFYNTDAYFRFVD
QCQAMDINIPIVPGVMPIYNYTQLARFSSVCGADIPRWLRLRLQDFGDDLPSLRSFGMDV
VTELSERLIAGGAPGLHFYTLNQAGIISTIMQRLSLPAR
>A0A1H4UJN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides exalbidus|TrEMBL
MDAAARIRAGQGDVVLFAITPPRRSTAAERLPEIARATLDRLEPLDLDGLVLYDIDDESD
RNPAERPFPFSPTVDPSDFRAAHLGSWQRPAVVYRAIGKHDRDSMRAWFAAQDPGRTLTV
LVGASSSDTVAPVTLAEAQQLRAEVNPDLLLGGVAIPERHSRREDEHLRMLAKQQAGCRF
FVSQVVYDVNATKNLVSDYFYECESQGVAPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLRHSANPLRASLEQAASAATEIADFCRSLGVPFGLNVESVSIRREEIEASVALAARL
TPLVRPA
>A0A3R6QAT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF20-7|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPDLCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A1G5JST0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium caeni|TrEMBL
MKVTEHIQNAQGKSLFSFEILPPVKGQNIQSIFDGIDPLMEFDPPFIDVTYHREEIELKE
LPNGLLEKKIVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDIDFLGIQN
VVALRGDAIKSEIYFKPEREGHHYATELVSQISNLNNGIYLDADLQNTSKTDFCIGVAGY
PEKHMEAPSIDSDIYFLKQKIKNGADYIITQMFYDNQKYFDYVAKVRAAGITVPIIPGLK
PIATKKQLNLIPHRFKVDLPDDLIMAVVKAKDNDAVKQIGIEWCIAQSKELVKAGTPVLH
YYSMGKAENIKAIAQAVF
>A0A1Z8Y6Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium TMED75|TrEMBL
MHFKDVYQTKDTTFSFEFFPPKTGNGWTVLEEAISKLVPLNPDFVSVTYGAGGSTRDRTH
ELVLKLQENQMLDPIPHLTCVEHTKQEIQQILERYAQAGVSNILALRGDVPVDSSVKNPF
EHFAHAADLVGTIKEFNHSGIHADSRGFGISVAGFPEGHPETPNTLTQMDHLKAKVDMGA
DVIFTQLFFDNNAFFDWRERCTLAGIDVPIVAGIMPIVSMQGLNRMADLAAGTRFPASLL
RALERGQDDPESVRRIGTHWATEQCLDLLDKGVSGIHFYTLNKSEATLEIFKTLGMKSV
>A0A562I4H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora olivasterospora|TrEMBL
MALGLPSVLPNSQPAIGELVRDRQPTFSFEFFPPKTPAGERLLWQAIRELEPLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVR
GDPPGNPGGEWVRHPEGVLYAEELVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQLGTIERSVQLSGAPF
PPALAARFEAVADDPEAVRRLGIEQAAQMCRRLLDEGVAGIHFITLNRSTATREVWQQLQ
VGARV
>A0A1B2FBW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMAVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKEELRTLIAQYKAAGIKRIVALRGDLPSGMGMAYGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQARNFESDLANFVHKVKAGADSAITQYFFNAESYFY
FVERVQQMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A0M9CGG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter dokdonensis DSW-5|TrEMBL
MKITEHIKKANEKTLFSFEIIPPKKGKSIEDLYANIDPLMEFKPPFIDVTTSREEYVYVE
KEGLLDRKVTRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMSHQKYFEASKGGHQYAKELVSQIQNLNKGKYLHDVIESDNCADFCIGVAGYP
EKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEAAKNIGITIPIIPGIKP
IAVKKHLQLLPQVFRIDIPENLIKEVDACKTNKEVRQVGIEFAIQQSKELLAAGVPVLHY
YSMGKSDNIQAIAKELF
>K0NML3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula toluolica (strain DSM 7467 / Tol2)|TrEMBL
MRVNELYKNKQPVISMEFFPPRNQAASEKFGGLIDTLAAYNPDYMSITFGAGGSTRDGSY
QTVKELIVDKKMPTVAYIAGYGLGPDDIREVLDSYRELGVETIFVIRGDQPKTDDAALHP
DSFLYASDLISFIKSNYDFTLGCAGYPEGHIEAKNLDQDIQYLKQKVDNGAEYVVAQYFY
DNDYFFNYVDKCKDQGINVPIIPGIMPVYTVKMTRMLSKICGSAITDELDQKLNSLDSED
KEGAVKLGIDFAAEQCRGLLKQGVPGLHFYTMDRSKSTGEIIAQLKQENLL
>A0A4R8X7Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT2-4|TrEMBL
MPHTSDPACRKIPFSFELYPPTSDAATSVLHATIERLAAAGPEFISVTYGANGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSNAESSQLIREFLDAGVRSFLALRGDPPEGIREGEAF
LGDLGSAAELVQLIHRVQAERVPYREAVIPGLPAARTIKREREKVRIAVAAFPNGHPRSR
SATQDIDALLAKQAAGANLAITQLFFHADHYLSFILRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRQATELARQLIAGGAPGLHLYAFNQHE
TVLAVLDGCGLLTPTLPASALPAPHPVKENS
>A0A8H7L9I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metschnikowia persimmonesis|TrEMBL
MATVIERIKALKPDEKFCLFEFFPPKTDTGFRNLLARLHRMMALNPLFFTVTWGAGGSTS
EKSLDLAATCQKELGVTTVLHLTCTNTNKEVIDNALAKAKEAGVRNILALRGDPPRTQEY
WTPNCDFKNAIDLVRYIKEQYGDYFCIGVAGYPEGHVDGANETQQNPRKDLPFLVEKVKA
GADFIITQLFFDVDKFVAYENLLQSVPELASVVLIPGLMPITTHKVFVRATKLSHALVPR
EISDRLEAPGNDDDMVKSIGIDVLTKLISEVNRKTEGRIKGYHFYTLNLEKAVAFIIERS
PLLNLVDHNQAVDHEDAIGSDSDSEEPVKVTTRKTRRSLTVEDAQLALISDAFSKDRKKI
IDISTGKGVLGKDATWDEFPNGRFGDSNSPAYGEIDGYGPNLKLHTPEQIYLSGKINVLP
WVDTEISSETALIQEELFELNQRGWFTLASQPAVNACPSTDKILGWGPSNGYLFQKAFVE
FFIPKKDWDEKLAPKLSQHIEEKTITFYKGDRSGNITSNLPIGENHQNSKTAITWGVFPS
KEVLQPTVIDYESFKAWNEEAFLLWVEWARCYKKDTEAYKLLESIYKDHYLISMIYHDFT
DEYGLWTSLLSD
>A0A5B8AZZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 8|TrEMBL
MTSARPPQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYN
RAKIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLG
GAAMGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRVMRDNGKFLSGRKLTTPPQ
VFLGAAINPFAPPYDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQRVRDLGYTEKLF
ILCGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPG
VSGVHVMAYRQEEYVAEIVDESGVLKGRRPWIREVRADDALVAERLGRLLHDDITETQVD
MVKSAH
>C3BPZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pseudomycoides DSM 12442|TrEMBL
MKILDLVSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADIIQTN
TYGANEAKLRMYGLENQVTQINKAAVKLAKAAVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEKVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQLALHEAGATQNGN
DVNGILTQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPAHIEGMKRVIANVTPVTEKQIVQRQQVVH
IQTKRASTHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIEEIYEATKHLEKPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMDGHETQESAIEEGIRISQELINAAMKYFNGIYLITPFLKYEITENLVKYVK
EKQDVKEGIN
>A0A7C8AUX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonadales bacterium|TrEMBL
MKRIRHWSARHARTMESLYNGFCSVAPVFRPMIAMIGKKQAEPLLARLEQGIKGTLFDCR
MCGECTLSASGMACPMNCGKQLRNGPCGGVTASGGCEIFPEMHCVWIEALDGSRLMANSA
AGRQVQPPVDHSKRGSSTWLKIIVNEPDAAKKGAHERVPMKAHAVGSLERACNSGRPVVT
VEISPPDSVNPQDLLHRAEVFRGLVDAINVTDNAGANCHMSSLAASAILASAGHAPVFQS
ACRDRNRIAVQADIMGAAALGVQNILCITGDGVGSGDHPQALPVFDLDSVSMLGIARGMR
DHGTYASGRKLHSRPELFLGATMNPFAPPYDDRIINLEKKIAAGAQFIQTQFCFDVKMFA
SFMREVRLRGLDRQSHILAGVGPLPSARTARWLKTHVPGVHIPDALIARMAYAEDQKREG
VAICKEIIRALKEIEGVAGYHLMGHKNEQLLAEIIVDTGLADRSDANESSHYRDNMEDRL
VA
>A0A7T0GL55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sarcina sp. JB2|TrEMBL
MRISEIFNKKEVVISFEIFPPKPNGDVNKIYNTLDELKILNPDYISVTYGAGGSFINNKT
IDLASKVKNEYNIESVAHLTCIKSTKKDIDKILKLLKNNNIENILALRGDVTGNCTCGDF
KYASDLISYVKMYNDFNIAGACYPEGHPACITLDEDIRNLKLKVDCGVNNLVSQLFFDNN
IFYNFLDKVYSANIDVPIQSGVMPVVNKKQIERIISLCGATFPKKFMKIVDKYEYDAIAL
RDAGIAYSVEQIIDLVSSGVKGVHIYTMNNPIVAKSIIKNISSIVSCINKRSIDEFGRN
>A0A396QBM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. OM02-18AC|TrEMBL
MKIRDILAKNEPTLSFEVFPPKTEDKYESVEAAAFEIAKLNPAFMSVTYGAGGGTSQYTV
NIAASLKAKGVTPLAHLTCVSSTREKVHSVLNQLKAEGIENVLALRGDIPKDGKVEKDYR
YASELIAEIKASGDFCIGAACYPEGHVESANKTEDIQHLKEKVEAGCDFVTTQMFFDNNI
LYNYLYRVREKGITVPVIAGIMPVTNVAQIKRICSMSGTYLPARFKAIVDRFGDNPAAMK
QAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNSLSEIIR
>A0A560HTQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirillum amazonense|TrEMBL
MTIVTETAADTPLARQLGGGEPLVTVPRDLRVSFEFFPPKTEKMEQTLWQAIRRLAPLSP
AFVSVTYGAGGSTRERTHATVTAIQQQTGIPAAAHLTCVAATKEEIDTIARAYWDAGIRH
IVALRGDPPQAADGSGGLGGSGYQPHPGGYAYATDLVAGLKRVADFEISVACFPETHPEA
VSAAADIDNLRRKVDAGATRAISQFFFDTDRFLRFRDTVAAAGIDIPIVPGILPITNFGR
AVELGAKCNCVVPAWMEDLFGGLDAEPETRQLVAATVAVQQCLRLEREGVRDFHFYTLNR
ADLTVAICHMLGVRAPKAV
>G3IV02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacter tundripaludum (strain ATCC BAA-1195 / DSM 17260 / SV96)|TrEMBL
MQSQKTHPKLFSFEFYPPKTEEGAASLQVVHSKLAKLNPDFFSVTFGAGGSTRDKTFTTV
VDIQSKGISAAPHLSCVASTKANIRAILKDYQDNGITKIVALRGDLPSGMMSAGEFRYAN
ELVEFIRQETGDHFQIHVAAYPEVHPQAASGVEDFKNFKRKVAAGANAVITQYFYNAEAY
FHFVDACEKNGITIPIVPGIMPITQYTQLFRFSEMCGADIPRWLRKRLESFGDDRESVQA
FGLDVVSNLCQRLLEGGAPGLHFYTMNQAAPTLAILENLQIRPQG
>A0A4R6YBZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydromonas duriensis|TrEMBL
MAIQIPISFEFFPPKTPEGEQKLNQTISDLSGYHPEFFSCTYGAGGSTQDGTFKTVAHIR
SLGYDAAPHLSCVGSTRDHIAQILQELKAQGVRRIVALRGDLPSGMGGTGELHHANDLVS
FIREQTGDWFHIEVAAYPEYHPQARSPADDLKHFINKMNAGANSAITQYFYNADAYETFV
NAVRAAGVNAPIVPGIMPITNYSQLARFSDVCGAELPRWVRLKLASFGDDRASILAFGQD
VVSHLCERLIALGAPSLHFYTLNQAKPSLAIIDAL
>A0A522GUT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beijerinckiaceae bacterium|TrEMBL
MDSTAPRASHSTCSGIDVSFEFFPPQTEDMEQILWSSIERLEPLRPSFVSVTYGAGGKTR
ERTHATVARILNETSIKPAAHLTCVGASCEEVDAVARDYWDLGVRHIVALRGDPQNGPGT
NFEAHERGYANSAALVAGLKKLGDFEITVSAYPEGHPESLNAGRDIDVLKAKIDAGATRA
ITQFFFENECYLRFLDKVRAKGIDIPILPGIVPVQNFRQTANFARRAGASIPSWLAERFE
GLDDDVTTRRLIAATVTAEQVFDLVDQGINHFHFYTMNRADLVYAICHLLGVRPQREVSL
SPLAKAGNERMRSG
>G0PZG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ACT-1|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A2B7X5S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomyces parvus|TrEMBL
MEKISDKIAALPRDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTYAVDLVKYIRRTHGDYFCIGVAAYPEGHSDESYPAAQDPARDIPYL
VEKTRAGADFIMTQLTYDLEAYKRFENMLRNHESGVFKTIPIITGLMPIQSYHILTRTTK
LSHAKVPPNIMTRVEEVKLDDESVKRIGVDILCEIVNGIKEIPCPGPRGLHFYTLNLEKA
VAFTVERCNLIPPSSEPSSDSEADLDTAVSMVHGQLNNIARISKRRASSINSLPHNRLIV
DRPSDGRGSSQASTTHETQALGAGMPALNPPHRATALQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVNATVARRLWGYPTTKRDIDTIFQRHVSGDLHIVPWSEGGT
QDTGGLNAETATIRDELLQLINRRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAF
VEFFCTSQDFKTILKSIFEKHGHDELAWFATNATGDFQSSSPPSEDSATDYSGPVDVYLD
SNATSSGTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRVFPRGGPTER
LLEQLKNDAWLVCVVGQKYGAGCQSEEDAEAERKLLWKLLAGQGTEAESTNKH
>G0ADZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas fungivorans (strain Ter331)|TrEMBL
MSQKNAQKNFSIEFFPPKTPEGAEKLRVTRAKLAELHPRYFSVTFGAGGSTQKGTLDTVL
DIRSEGHEAAPHLSCLGSSRESLRTILAQYKDHGIKRLVALRGDLPSGYGAMDISSGEFR
YANELVEFIRAETGDWFHIEVAAYPEMHPQAKSPQDDVQRFVSKVKAGANGAITQYFYNA
DAYFRFVDEAQKLGAAVPVIAGIMPITNYSQLMRFSDMCGTEIPRWIRLKLASYGDDSDS
IRAFGLDVVTQLCERLLAGGAPGLHFYTLNQSPATIAIWQRLKL
>A0A4Y3TMB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter orleanensis|TrEMBL
MSLSRLSVELIPRSEEALAQDVASVKTLLPAADTLNIPDLMRFPLRSWDAACLTMPQFGT
VIPHVRAIDIAPGAPLPGSTLPGLKEVLVVHGDPPADLAHQTYPNSTESIIRRYRKEAPH
LRIYAAFDPYRRAPWKELEDIARKKEAGADGFFTQPVFDLKLFDLCREWLLGEQVFWGLS
PVIGPRSRSYWETTNHVVFPRNFEPTLDANIQFAQSVLRQLSQDQGCAYLMPLRVKLEQY
LPPLMDAIQG
>A0A7C1P883|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium albertimagni|TrEMBL
MTKPERPIAKTPDVRISFEFFPPKSPDMEDQLWQTVQALQPYQPDFVSVTYGAGGTTREP
TLATVKRLIADTPLATASHLTCVGATRDEVRAVVEEFQAAGVRHFVALRGDPQGGMGSRY
APHPGGFVNAADLVSGLRDLGDFEISVSAYPERHPESENDDVDLDMLKQKVDAGATRALT
QFFFDNDIFERYLERVRAAGITIPIVPGIMPIQNLTQLKRFASMCGASTPSFLDERFEGT
EGDAQARAAVAADIAAEQIADLSRRGIEEFHIYTMNRAPLTIATLERLGIAAKVGEVSNA
AA
>A0A7H8PAA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NA03103|TrEMBL
MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPTADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPKLSNASF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A2I4CJP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Austrofundulus limnaeus|TrEMBL
MVNHGQRVDGGWPSGRSDSSSTSNSGGESSKESSRCSTPVLDSDRSDRLRDKMRRRAESG
DRWFSLEFFPPRTAGGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESVLHLTCCNQTKDRITAYLAKAKHLGLKNIMALRGDPVGSDWEEEEEGFNYAV
DLVKHIRSEFNDYFDVCVAGYPTGHPEAASYEDDLRHLKEKVDAGADFIITQLFFRADNF
LKFLEDCRTIGVTCPVLPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRN
YGIHQAVEMCRVLLDSGKVPGLHFYTLNREVATIEVLRQLGLWIEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEA
LLKMWGEELKNEGSVFDVFTCYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPVVGWGPAGGYVFQKAYLEFFTSSENVTALLKVVKKYEPRV
NYHIVNVHGQNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFGLWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWRIIDDMFELLDTPPQTLGGETQS
SVTQSSETLPE
>A0A7K4N3T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marine Group I thaumarchaeote|TrEMBL
MTVRYEINPPKISDDGQDVRNVLFERIETISSVCNGIHLTDSVLGIPRVSPFEIAKQIRE
SNKNIKLTCSLRVRDKNLNDIEKIVQESIGTVDGILVLMGDKSDTMSNKDNLIPSQVVKA
LNDNGLDKKIELFLSLPSNPNFAKIQKKIDAKPVGFVTQVIHSKDQVEKIVNYLRPNGFK
IIPCLLLPSQNNLKSAEFLKIDWSNYEENIIEFINEIHSITSEILVTSPNDFKRAHETLT
KLAT
>A0A847S0I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga varians|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMDFKPAYINVTYHRSEHMFKKK
ADGAFEKVEIRKRPGTVGICAAIMNHYTVDAVPHLICGGFSREETENALIDLAFLGIDNV
LVLRGDAPKNETFFEPDPHGHSYASELLDQVVHMNNGVYLEDDLQGGVKTNFCIGVAGYP
EKHFEAPNMQTDMGYLKRKVEMGADYIVTQMFFDNQKFFDFVAKCREMGITVPIIPGLKP
LTSKKQMNILPRIFHVDLPTELSSEIMRCKTDKEVEQVGTEWLIQQSKELKAFGVPVLHY
YTLGKPQVVRKAVEAIV
>A0A848HA12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ramlibacter agri|TrEMBL
MMLPLSLEFFPPKTAEGSDKLRAARKQLYALKPDFCSVTYGAGGSTQAGTFTAVTEILAE
GVDAASHFSCVGATRAKVRDQLEVLRSMGVKRLVALRGDLPSGYGIGGEFLYASELVEFI
RAETGDAFRIEVACYPEIHPQAKSPDADMKAFVTKVKAGADSAITQYFYSADAYFRFVDE
ARKLGVAVPIVPGIMPITNSSQLLRFSDACGAEVPRWIRLRLQSFGDDVKAIRAFGLDVV
AALCEQLQRGGAPGLHFYTMNQAGPTLALCERLA
>A0A1V5QDP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium ADurb.Bin345|TrEMBL
MSKRISDLLANRSRPLLSIEFFPPKDHKGFAILGSSIERMRVIRPDFVTVTYGAGGSTRD
LSPVVSEVLGKMGFSPIMPHLTCLGSTRQDLEPVADRMYEAGYRNIMAIRGDPPQDQPGF
KPPKDGLLYASELVAFLKNRYPDLCCGVAGYPETHPEAESPEADIRHLKEKLDAGGSFVV
TQLFYDNAVYFDFVTRCRRAGIEAPIIPGLLPAVSLSQAQRMSSRCKASFPAELAEQLEK
AGGSGPVAEAIGIQWTVKQIDGLLAQGVPGVHLYILNRAKTALAPALEECLSRWR
>A0A0Q4SYL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. Leaf82|TrEMBL
MKVTEHIENAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCNYLGIDN
VMALRGDAMKDEQYFMPKAGGNDYAIDLVKQISLLNQGKYLHEVMDADNRANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNSKYFSFVEKAREMGITIPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDSCKNNAEIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASHLF
>A0A345NR07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ornithinimicrobium avium|TrEMBL
MSGAVDLAVRRLLEGARYEVLPTASIHDQVLEHVPTSVTVSVTASPGKRLGATLDLSASL
ATAGYDVVPHLAARMVSGRAELVDIVEQLRELGVRRVFVPAGDAQVPVGDYVQALDLLHD
LRDMGDPFPEVSITGYPEAHPFIEDDVVVQAMWDKRLHATHVVSNMTFDPEILAAWVHRI
RRRGVNLPLLAGVPGPVERTKLLAMGTKIGVGDSLRFLRKQRKVMTRVVGSGFSTDRFVT
SVAGLAADPAMGVAGLHVYTFNQVGVVEAWRRAALSHEARGAHGRSAARG
>A0A0E0GVI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryza nivara|TrEMBL
MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLK
QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEDAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNL
GLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNP
SYGALTDYQFTRPRGRGKKLQEEWAVPVKSVEDINERFMNFCQGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLD
QLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWK
DEAFEIWSKGWACLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAFKEI
>C2KHN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc mesenteroides subsp. cremoris ATCC 19254|TrEMBL
MTRITDIYKKKSAPVLSFEIFPPKTEDGLHALYKTLQEVNPKETGVDYISVTYGAGGGSN
HKRTKEIAEYIERNCGITALHNLTGINQTPSSLKGNLEKISVAGVENIFALRGDTPTKDY
VNEYYPFAKDLIKEIKKDGRFDIGAAIYPEGHVDNPTTGISVTGVKEKVISGTEFLISQL
FFDNGVFYNMQEALKENYIKVPVSAGILPIISRAQVERITYMIGSSLPARLAKIVHKYED
QPEALQQAGIEYALEQIHDLLDHGVDGIHLYAMNQPNVLKIMLPEINRHIQSKILTL
>A0A0N0CSG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MRNQTFSVEIEANPGDLRQMKHYLHKWQPDFVSISNLSRYSYEEMVQCARYIQTDLHIPV
VIHLTGLTHTKEQVKKAFNQLMDLNIRNFLLVRGNIHHNMHIEDDFNYASDLIKYVNQLD
TDSKINVVAGCYPDIHVLADSLTEDIEYLKQKVNSGVDSLISLMCFDNKRIYKFLDKSRE
FGINVPIRIGIMPITDPFKKDYLAHNDVKMPEFSKEEDNLLEDGIEFAVKQINDLYEHNV
NGIHLYTHNDWMVSDRVFENIKQNL
>A0A258VKV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadales bacterium 28-64-96|TrEMBL
MSLTLNQMAEAARALNGPLFADLPGDLAVSFEFFPPKTPAMQESLWQAVETLVPLAPRFV
SVTYGAGGSTRERTHATVARIVQETPIPAAAHLTCVNATAEELDQIADEYWAAGVRHIVA
LRGDPPGGQAGFQPVPGGYASAAELVAALKRRHDFEISVSCYPETHPEAGSLARDLDALK
AKHDAGATRAISQFFFEPDTFFRFRDKVAAAGLDVELVPGILPVSNYANLKKMAVSCGTH
LPEWMGRLFDGLDDKPAARQLVAATVAAEMSRRLYAGGVRHFHFYTLNRAELSYAICHLL
GVRPAQELAA
>A0A258G108|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. 32-62-10|TrEMBL
MTITINQLEEARRALDAPLFADLAGDANVSFEFFPPKTEKMEEALWETVKTLAPFGPRFV
SVTYGAGGTTRERTHATVARIQRETPMPAAAHLTCVEASRDEIDAIADAYWQAGVRHIVA
LRGDAPGSSGFVPHPEGYTNAADLVAGLKRLHPFEISVAAYPECHPDSRDEADDLDNLKR
KLDAGATRGITQFFFEPETFFRFRDRVSVAGIDAEMVPGIMPVTNFASILKMSAMCGTAV
PPWLGRLFEGLDDHPTSRQLIAATLAAELCRKLYAGGVRDLHFYTLNRAELSFAICHLLG
LRAKAAPLVAVNAAA
>A0A1H8CSJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudorhodobacter antarcticus|TrEMBL
MTKTPNISFEFFPPQTLDASFRLWETVQVLAPLAPTFASVTYGAGGTTRKLTHEAVATIG
SHYGLNVAAHLTCVDATRAETLEIAESYAAAGVTEIVALRGDAPKGAARFTPHPDGFASS
VELVAALAETGKFKLRVGAYPEPHPDSADTLADVQFLKRKIDAGATSAITQFFFEAETFL
RFRDACVKAGITAPILPGILPIQSWEGTKKFAARCGTQVPAWLDDAFVAAKRDGREALLA
TALCTELCDELLGEGVQDLHFYTLNKPHLTRDVCHALGISPQVALQNVA
>A0A1E3IN67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus depauperatus CBS 7841|TrEMBL
MTKLTDLIASRREPFHNFEFFPPLTEAGLVNLLDRIHRLTSSPLPRPLIVSVTWGAGGST
SDKSLELAERIFKMGVEVMLHLTCTNMPKEKIDFTLQRCKEIGIQNILALRGDPPRSEEY
AISTPLPDFFKHADDLVRYIRAEHGSYFCIGVAGYPTLHPDSKSEEAEFKWLKVKCDAGA
DFIVTQLFYDTEGFLDWVKTCRAQGISLSIIPGIMPIQSFASFRRLVNLTKTPIPFSITA
DLQPISADDAAVKRYGAELATKMVRRILDSGFVSGVHFCTLNLEKSVWTILDNLGWMEER
HGKSAPRNKVIENDGHSDGISMNGKAPNHAASHTSNLSISPSEASYIAQLGFHTLPPAPK
NGLGTQGGNNGEDSWDEYPNGRFTDVRSPAYGEIDGWGSGLKITGTQVLKEWGVPTSVAD
LSALFISYLRSDIQAPTTPFCDLPLSPESHSILPHLISLNSTESQHWTVGSQPAVDAAKS
EDPVFGWGPRGGYVFQKAFVEFFVREDEVKRLEEKVKLAGGTITMYAANKAGGFKSNTES
DAVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFSIWTDWSLLYPPHSSARKLLEGIAS
EWWLVSLIHHDYKDKEALWNFLLKDQN
>A0A5F0G095|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT2-16|TrEMBL
MPHTSDPACRKIPFSFELYPPTSDAATSVLHATIERLAAAGPEFISVTYGANGSSRRSSL
DVLTHILRTTTVDPLAHLTCVGSSNAESSQLIREFLDAGVRSFLALRGDPPEGIREGEAF
LGDLGSAAELVQLIHRVQAERVPYREAVIPGLPAARTIKREREKVRIAVAAFPNGHPRSR
SATQDIDALLAKQAAGANLAITQLFFHADHYLSFILRARAAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIALEVEPTKEGQREIGIRQATELARQLIAGGAPGLHLYAFNQHE
TVLAVLDGCGLLTPTLPASALPAPHPVKENS
>A0A016AJ32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis str. 3976T8|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYRDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A7W0MRZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
MNLIRRIDAGQGEFLLFALTPPRLATDRERAQEIADVTVARLRPLGLDGLILYDIDDETE
RNPAERPFPFMPTLDPADYLAKHVGTWPTPVIVYRAVSKYAPTDLRAWLSAQDPERLMTV
LVGAASSGAQVRTSLRDAQALRREVNPGLLLGGVAIPERHTRRDDEHLQLLAKQDAGCRF
FVTQVVYDINAAKNLVSDYHYECSARGISPAPFVFTFSVCGSMKTLDFLRWLGVDVPRWI
ENDLRHAADTLEASYQQALTTATELMTYCRTLGVPFGINVESVSIRRVEIEASVRLAQEL
RTRLKR
>A0A2T3G746|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacillus intestinalis|TrEMBL
MKINELLNKRPTLSFEIFPPKNNENDITSIYATIDELAKLNPDFISVTYGANGSTSKNTC
KIASTIKKKYGIESVAHLTCMNNTKDEIKEILEELKENGIENVLSLRGDYPKDSDGINHG
DFKYASELNEFIEENFPNDFCLSGGCYPETHYEAKNFEEDLLNLKKKVDAGAKYLVTQIF
YDNQYYYRLVREARKIGIHVPILAGIMPAHNPKQLKNIAKMSNCSVPFDLAAMIDRFAGN
PKAGREVGLHYATYQIIDLMTHGVDGIHIYTMNKPEIAKEILKRTEYIRDEFFKA
>A0A183DBV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gongylonema pulchrum|TrEMBL
LYRFRALDMIRWIKEEYGDYFTIACSGYPTGHPEAPSYRADLLYLKSKVEAGADFIITQL
FFDSEVYEKFLRDCREIGITVPIIPGILPIQSYGSIRRITEMSQLVIPDWIRSALEPIKN
DDEAVRNFGIRHAVDLCRALFRSGSAPSVHLYTLNREASCR
>A0A8H7ZLW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olpidium bornovanus|TrEMBL
MERMARLGPSFISVTWPATGSDTAAAIKTVELCATAAQEFGLVPCCHLTCTNTRRETINA
ALDDMKRSGVRNIFALRGDPPRDAEHWEPTDASFRYAVDLVRHVRKRHGSYFCVGVAAYP
EGHPDNDRPQDELQRLKEKVDAGADFIITQFYFDVDAFIKWVKAVRDAGKITVKLTTEHG
IWRAASAGCDFLFQHSLIAAPVLACQTSHICIRHHRSCHCRDHANSRLRVFQNVDPPYKS
CAFTVARFSTLQILHLQQYDDAAIKTFGVTCAASIVSCLCEAGVQGFHLSTLNLEWSVRR
ILLETGYIEEVRIRTDFVKPTSNVTTLAEKTRESVVRGLFGPHPQSPELWDDFPNGRFGD
SRSPGEKLQRFG
>A0A6P0N8N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIO3C2|TrEMBL
MTNPTNNSFRTAVESGEFLITAEVAPPKGGNAAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILHQQGIEAICQVACRDRNRIALQADLMGINALGIGNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQATDLFTGAAVDPQLKSWSGLQSRFEK
KLEAGAQFFQSQLICDFDRLEKFMDQIAAGTNKPILAGIFLLKSAKNAKFINKKVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKIAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSAVNDLVCK
>A0A834A8I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllostomus discolor|TrEMBL
MVNEPRGNSGPGAHWEGSSCGIENSKDSLKGSSPGLDPERRERLREKMKRKMESGDKWFS
LEFFPPRMAQGAVNLIAMFDQMGAGGPLFIDVTWRPTQDPGSDKETSSMTIASTAVNYCG
LETMLHMTCLCQSREAVTGHLRKARRLGLKNILALRGDPPGEQWEEEEGEFSHATDLVKH
IRSEFGDYFDICVAGYPKGHPDAVSFEDDLKHLKEKVTAGADFIITQLFFEADTFFLFVD
ACSKIGITCPILPGIFLIQSYHSLRQLMKLSKLEVPQSIRDVIEPIKDNDDAICNYGIDQ
AVSLCRKLLASGLVPGLHFYTLNRLKATTEVLKRLGMWTEEPRRPLPWALSAHPKRREED
VRPIFWASRPKSYIYRTRDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKAPREELLKMW
GEQLSSEKSVFDVFVRYLSGEPNQNGHPVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPRVNGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLRVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWVERWGKLYDE
KSPSRRIIQHIHDNYFLVNLVDNEFPLDSCLWQVLEDTLELLNRPMSE
>A0A7Y0FZA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. R302|TrEMBL
MALGTASVRTDRARTVREILAAGTSYSFEFYAPRTAKGEQVLWNAMRRVEAVGPSFVSVT
YGAGGSTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNVLGQYADAGIRNMLALRG
DPPGDPLGDWVEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVDK
CRAGADYAVTQMFFDPENYLRLRDSVEKAGCETPIIPEVMPVVNVKTLDRLPQLSNAAFP
ADVKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNSSTATLEIYENLGL
HQQS
>A0A198GYA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter soli ATCC BAA-2102|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A482Z271|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium endosymbiont of Bathymodiolus sp. 5 South|TrEMBL
ELSSLNPEYFSVTFGALGTTQEVTLETVLDIQKNDTVAAAPHLSCIGSKKEIIITLLDQY
KAANINRLVALRGDIPSGVRDIGDFHYANELVEFVKSQYNNHFHIEVAAYPEMHPESKNR
LTDLQHFADKVSAGADGAITQYFYDADAYFKFVDATEKLGINIPIVPGIMPITNYTQLVR
FSNMCGAKIPSWILKKLELYQDDLDSLSAFGLEVVTNLCQTLKAQGVDNFHFYSMNHSQP
SLEIAKHL
>A0A3P2A5T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Conchiformibius steedae|TrEMBL
MKTYAPKLSFEFFPTRTPEGRAKQVVTRKQLSQFRPDFFSCTSGAGGSTREGTLQTVQDI
LNEGTPAAPHLPCIGMDAGEIKELLQQYKQMGVRHLVALRGDIPSGIGSGMGGLRYANEL
VELVKNEFGNDFHIEVAAYPEYHPQSRSAEDDINHFVRKVKAGADSAITQYFYNADAYFR
FVDDVQGRGVDIPIVPGIMPVASFSKLARFSDACGAEIPRWLRLKLQSYADDTAAIKALA
LDVVTEMCARLLREGAPGLHFYTLNQAGLSSTICQRLGY
>A0A315B2V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. WS1|TrEMBL
MSGLKLPISLEFFPPKTPEGAEKLRGVREKLYALKPEFCSVTYGAGGSTQEGTFSTVSAI
LSEGVAAASHFSCIGATKASVREELATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLV
AFIRAETGDDFHIEVAAYPEIHPQAKSPESDLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGYGDDVESIKAFGL
DVVSDLCEQLMNGGVPAIHFYTMNQSASTTEIVRRCNL
>A0A4Q0P8S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leeuwenhoekiella marinoflava|TrEMBL
MKITDHIKKANGKTLFSFELIPPRKGKSIQELYNNIDPLMEFKPPFIDVTTSREEFVYIE
KDGLLDKKVTRMRPGTIGICASIKHKYNVDTVPHVLCGGFTKEETEYMLVDCHYLGIHNL
MALRGDAMREEQYFKPTPGGHEYALGLVEQVAEMNKGHYLNGMVETSDCSDFCIGVAGYP
EKHLEAPSLKTDLKRLIQKVEAGADYVVTQMFFDNKKYFEFVDLVRAEGIDIPIIPGIKP
IAVKRHLQLLPQVFKIDLPQELIESVESCKNNADVRQVGIEWAIQQSKELMEGGAPVLHY
YSMGKSDNVQAIASALF
>A0A2A6JHX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium chutanense|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWQTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGVSIPIVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIGDFHLYTMNRSPLVSAVLDNLGLSRRPAKSAGAAA
>A0A2Z6AFA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. YG1|TrEMBL
MTLNDPRHNAPIGPLYADLAGDARVSFEFFPPKTEKMEAQLWSAIETLAPLAPKFVSVTY
GAGGSTRERTHNTVARIAKATSLAAAAHLTCVAASKDEIGEIADAYWDAGVRHIVALRGD
PPEVGSRFEPHPDGYTGAADLVEGLMKRHPFEISVSAYPEVHPDAASAQSDLDNLKRKLD
AGATRAITQFFFSPDAYFRFMDKVGAAGITADIVPGIMPVSNFAATKRMAAMCNTDVPLW
MARLFEGLDEHPASRQLVSATIAAELCRKLYEGGVRDFHFYTLNRAELSFAICHLLGLRA
KVAVNA
>X7RXR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum 13_3C|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEIGD
FNYAKDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A2T2NTN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynespora cassiicola Philippines|TrEMBL
MHISQKLAQARAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDVTWGAGGRLS
HLTVEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALKEAYNAGCTNILALRGDPPREKEK
WEATTGGFRYAKDLVKYIRDRYGNHFDIGVAGYSEGCDDNRDVDELIDHLKEKVDAGATF
IVTQMFYDTDLFLEWVNKVRAKGVDVPIIPGIMPIHTYAAFLRRANWTQCNIPPHWTAAL
EPVKNDDVEVREVGKELVAEMCRKLIDAGITHLHFYTMNLAQATRMVLEELEMLPDVESP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDARSPAFGELDA
YGVGLKGTNEQNIKLWGTPKSIKDISDVFVRYMKGQLESLPWSEQAISTEASTIQENLID
LNRRGFFTINSQPAVNAAKSSDPVYGWGPRNGYVYQKAYLEVLVSPEHLAELITRIERNP
DLTYYAVNKDGDLKTNSPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQDW
ANCHPSISPSRYVIEDVMDTWYLVNIVHNDFHVQHGIFPLFDGLSVKDMEKELHSTGVQN
GHVENGEKHATNGQESHVNGAIDAIKSATSAVTNGISNVQLSN
>A0A674ANS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmo trutta|TrEMBL
VWCVCVCERENFSLSTLMTVWESNTVFILHGKRNSGGESSKESSRSSTPVLAADRTERLR
DKMRRRTESGDHWFSLEFFPPRTASGAVNLVSRFDRMGSGGPLFIDITWHPAGDPGSDKE
TSSMMIASTAVNYCGLESILHLTCCNQTKETITGYLSKAKHLGLKNIMALRGDPVGADWE
EEEGGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFII
TQLFFRTDTFLKFVRDCRAIGITCPILPGIFPIQGYQSLKQLVKLSKLEVPEEIMQVIEP
IKDNDAAIRNYGIEQTVGMCRVLLESGNVLGLHFYTLNREVATMEVLRQLGLWIEDPRRP
LPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLF
YLKSKSSKDALLKMWGEELTSEQSVYEVFTSYIKAQPNCAGHKVMCLPWNDEPLAPETNL
MMDKLDKVNRRGVLTINSQPTINGMPSDDPIVGWGPPGGYVFQKAYLEFFTSSENVTVLL
KVLKKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDE
AFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDNMFELLDNP
PEEQPTEQPAEQPAEESPVEDQPTK
>A0A2S3QBL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfobacillus sp. hq2|TrEMBL
MKSLADALRDPTWIIGDGASGTALMAAGIDPAALPLVPLRQPDTLMNLHLQYLEAGARLL
ETQTFSANGSKLAALGLEADVVLLHRRAAQIARHARDIFGEPAWIVGSIGPLAQPVASPV
MESLTHEEAVDYYRPVVAGLLAGGVDGFIVETMSDIPTVLAAVEAIREESLLPIIVSFAF
SPEGATRYGLTPEQAIEAMGQLPGGPPQLVGANCGSGPAPLLDAVIRMAPRAKDLQIPLA
AFPNAGQPAMVANHVHYPASPHYVATMAPALAEAGCRVIGGCCGTTAAHIQAIAQTLQHM
PVLPQVRTWNVEDEHAANETMGGEGAPEGIRQLFGKRFVVSVELDPPRGVNPHRVLEAAR
TVWEAGADAINIGDSPMARVRLSALATARLIAEQLPVETILHFTTRDRNLMGLQSDLLGA
HALGIRNVLALTGDPPGIGDYAHATAVYDINSIGLVKVLAGFNQGQDASGQKIGGHTAFD
IGVGVNPTAEDLDHEVLRLQQKLEAGAGFIMSQPIYAKEQLERFLDRFGPLPVPLLLGVM
PLVSYRQALYLHNEVPGITIGTEILAQFEHVQDGTALGIDMACALLDDLESVIQGVYLVP
SFNRVEPLLPLIAYIRQEFSTKKRS
>A0A1H0ITU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalicoccus daliensis|TrEMBL
MSFKQQLKEGLIVGDGAMGTLLYQRGSQSCFEELNLSDPEQITSVHQEYIAAGADVIQTN
TYAANSIKLDRYNLGAYVKEINEAAVAAAKQAGDVYVAATIGGVATMHQEKTPLEERVAS
LKEQTDVLLETDVDGFLLETFYDFEELKQILIYLRERTDKAIIAQATLGDIGVLHTGMHL
QEALELLENLGADVAGINCRMGPYHMLQSLEEISLLSHATISVYPNASLPNVRDGRFSYQ
SNPTYFGDMTKGLVEEGATLIGGCCGTTPDHIREIKKAIKEHQLKPVKEKRTRRPVKSDV
IRPEEPFFPKLTEIKDEMSVIVELDPPKALSGVPEFMKGAKALTEAGVNAVTLADNSLAS
SRIDNLALGSKIKDEGARPLLHIACRDRNIIGLQSHLLGMHELGVRDILAITGDPAKVGD
FPGATSVYDMSSMDLIRLIKQLNEGQSFSGKDLGANTNFTVGAAFNANARRLEREVQRLE
KKIEAGADYFMSQPVYSSERIEEIAEATKHLSVPVYIGIMPLVSSRNAEFLHHEVPGIKL
TDEVREQMREVAGDREASEKVGIDMAKQLVDTAMIHFSTIYLITPFLRYNITETLTKHIR
EHEKTIAGTRG
>A0A3Q2Y198|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hippocampus comes|TrEMBL
MVNQVQLGDGSCQSCKSDSSGMGTSGGESSKESSRCSTPVLDSDRSDRLRDKMRKRIESG
DHWFSLEFFPPRTTPGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTA
VNYCGLESILHLTCYNQTKDKITAYLAKAKHLGLKNIMALRGDPVGADWEEEEGCFNYAI
DLVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGANFVITQLFFRAETY
LKFLDDCRAVGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMEVIEPIKDNDAAIRN
YGIQLAVEMCRVLLQSGKVPGLHFYTLNREVATMEVLRQLGLWVEDPRRPLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKED
LLKMWGEELKNEASVYEVFTSYITAQPNRNGHKVMCLPWNDEPLAQETNLLKDELEKVNR
RGVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVSALLEVLKKYEPRV
NYHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTIVDPVSFMFWKDEAFALWIEQWA
KLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFEQLDASPQSPLHEVSS
>A0A444TIN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armadillidium vulgare|TrEMBL
MVKEMEEAVPNSTEDTLSILKGFIESRSRDSISESSSADSCLDCHIPKPDLIWGFPNLKE
KIVSRIESGDKFFSLEFFPPRTKGGAVNLLARFDRMRAGDPLFCDVTWHPAGNPGGDTET
SSMTIASAALNYCGLETMLHMTCCALTKTEIRNHLKRAKDIGIRNILALRGDLPCDVEDW
TPPEDGFRYSTDLVKFIRQEFGNYFVICVAGYPNGHPEAESYEEDIKHLKEKVDAGADFI
ITQLFFKAETFINFVKDCRKAGIEVPIIPGVMPIQSYDSLRNIVKLSKLDIPEEITDQVA
PLKDNDEAIRNYGVDQCCKLLRKIFNSGYAPGVHFYTLNREVATTTILKQLGLWSCSPKR
PFPWKMAANHKRCSEEVRPIFWASRPKAYVYRTQHWDEFPNGRWGSSESPAFGELKDYYL
FYLKSKSSKDELLAMWGETLESEQDVWKIFACYLTGQPNPSGNKVTMVPWNDNELSPETS
YLKEKLAYFNTKGILTINSQPNVNGASSEDEVVGWGMPGGYVYQKAYLEFFTCKENVEAL
KKVLPLFPRVNYHIINKDGSEDFF
>A0A3R7PML3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penaeus vannamei|TrEMBL
MVKEGATTLPSPGTPAALPILKDFLSHRDGNPVDYSHVDDDLHMPEYLTGYHSLREKIHS
RIESKDKFFSLEFFPPRTKGGAVNLLARFDRMREGDPLFCDITWHPAGNPGGDTETSSMT
IAGAALNYSGLETMLHMTCCSMTKAEISRHLQRAKDIGLKNILALRGDLPSGKDSWELSE
DGFNYATDLVKHIKKEFGDYFVTCVAGYPTGHPEATSYEDDLKHLKEKVDAGADFIITQL
FFKAGTFIKFVNDCRAIGITCPIIPGLMPIQSYDSLRHIVKLSKLDVPEDIMNVVAPLKD
NDEAIRNYGIHQMCTLIKELFAADMAPGIHFYTLNREVATTAILKQLGLWAASPRRPLPW
KMAANHKRSGEDVRPIFWATRPKAYVYRTQHWDEFPNGRWGASESPAFGELKDYYLFYLK
SKSSKEELLSMWGETLESEQDVWDVFHAYLTGALNKAGRKVTKVPWNDDELSSETSLLKD
KLADFNKRGVLTINSQPRVDGASSEDPVVGWGMPGGYVYQKAYLEFFTSKENVDALLNVL
PLFPRINYHILTKDGKADFSNCHQHRPMAVTWGVLGEIIQPTVVDPSSFKAWRDEAFGLW
DEQWGNLYPAESQSRQIISQITSTYYLVNLVDNDYQKESCLWDALEAMFAWRKLKEEKQD
EQKNEKDLCVCVQG
>A0A5N5JL55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salix brachista|TrEMBL
MKVIDKIRAAAAGGDANGSANGNGCDSSSNSKVVFSFEFFPPKTEDGVDNLFERMDRMVF
HNPSFCDITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDQALETIKSNG
IQNVLALRGDPPHGQDKFVQIQGGFSCALDLVKHIRSKYEAHPDMIGSDGFATLEDYHKD
LAYLKQKVDAGADLIVTQLFYDTNVFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTG
FCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALA
ILMNLGLIEESKITRPLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPHGRWG
DSRNPSYGALSDYQFMRPRARGKKLLEEWAAPLKSVEDIYEKFKVYCLGKLKSSPWSELD
GLQPETKIINEHLGKINLKGFLTINSQPAVNGEKSDSPSVGWGRPGGYVYQKAYLEFFCS
KDKLNAIVDKCKSFPFVTYIAVNKGGSWISNVALTDVNAVTWGVFPAKEIIQPTVVDPAS
FSVWKDEAFEIWSRGWASLYPEGDPSRMLLEEVQSSYFLVSLVDNDYIHGDIFAVFADL
>A0A1M6QA42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermocrinis minervae|TrEMBL
MKIIEHLRRGEFSLSFEFFPPKTQEGEEELFQTILDLRPLNPTFVSVTYGAGGSTRERTR
RIAQRIHTETDLTVMVHLTCIAHTKQELLEMLTSYKEMGIQNVLALRGDVPKADDFKPPE
GACKHADELVSLIRENFKDYFCVCVASYPEGHPESPNMEWEIKFFKKKVLKGADFSITQM
FFDNSYYYEFVELCRKEGINIPIIPGIMPITNFRQIQKFASMCGATIPQSLIDRMEPVAE
KPEEVAKIGIEFAIRQCEDLIRNKAPGLHFYTLNKSKATLEVYKAISGLIPRQR
>A0A3Q8DGA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. ASNIH4|TrEMBL
MGFHSARQVEALNQSLADLSGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPEMYATDLVALLKAEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDDDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQQ
>A0A1Z5K436|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fistulifera solaris|TrEMBL
MPRIIDKIARRREQFAVERARQPTYDAAEQQDNNSLPSGWFYSFEFFPPATEAGLDNLLT
RIDRMARRLDPFFINVTWGEKTATKSLAIASHAQKYLGLDVMLHLTAEGATREDIARALD
QARASGICNILALRGDPPRGKRPWAVGDVTSSDFPRAIDLVRFIRQLHGDYFCVAVAGHP
EGHSSSATPEEEIVHVKEKIDAGADMVLTQLFYDTELFLDFVRRCRAAGISCPIIPGIMP
IQSYTSFVKLTEYCRISVENDVWKEIEAIKGDDEAVKEFGCQLAAKMCRRILQASRTYSE
LGHLDGIHFYTMNLERSVSNILVAMEAVTFVRNANNTMQPSARRVFPWRPSAIDKREQNE
QVRPINWANRPKSYMIRTEDWDEFPNGRWGDSTSPAFGELSSVSHFFSFSLGSEHDQRVT
LGENPTSPRDVFEVFAQYVEGRIPSIPWCETQLQPESFFIQSALVMLNRAGYLTINSQPS
VNGIASTDPTFGWGGKGGLVYQKAYCECFCSPEHVQKLVALTQDSDSIQLYAVNCAGKEI
REGRKPGGITALTWGVFPNREILQPTIFDPTTFLVWAEEAFSLWTTMWLTLYDYESESYA
LIENIRDTFFLCAIIDNDFTVKEGENTLWKKMESIL
>A0A0J6SF95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium aquaticum|TrEMBL
MIPTAFRPSRESRRPIRVSFEFFPPKTPEMETTLWSSIERLAPLGPSFVSVTYGAGGSTR
ERTHNTVARLVRETELKPAAHLTCVAATKSEVDEVVGAYYEAGVRHIVALRGDPAEGVGT
AYTAHPGGYERSCDLVAGIKRIGDFEVSVSAYPERHPEAGSLDQDLDALKAKVDCGADRA
ITQFFFDNDLFFRYLDRVQSRGIDIPIIPGILPVQNFKQAASFARRTGASVPDWLAARFD
GLEDDVATRKLVAAAVAAEQVLDLVDRGITDFHFYTMNRADLVYAICHLLGLRAAPVVAE
KAAA
>A0A444CVS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensete ventricosum|TrEMBL
MTAAIGLQVQHIRAKYGDYFGITVAGYPVLKRVFSILEAHPDMIQGDGGATLDAYDSDLA
YLKRKVICYIIFVYMIIVHYDLTNNILQIPSEITAALEPIKDNEEAVRAYGVHLGTETCR
KILAHGIKTLHLYTLNMEKSALAILMNLGLIEESKVSRSLPWRRPANVFRVKEDVRPIFW
YHLLFIFRHLRITWLLPVLWMMLEGYGLDLFLFADLNRANRPKSYISRTVGWDQYPHGRW
GDSNNPSYGALTDYQIFMKFCLGKLRSSPWSELDGLQPETKIIDEQLSLVNLKGFLTINS
QPAVNGEKSDSSAVGKLSNTLFKCLMSDSCCFLILFVIVSHSQAQRSYYLVSLVDNDYVH
GDIFAAFKDI
>A0A2H0ZBT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG08_land_8_20_14_0_20_51_18|TrEMBL
MKITDILKKKKTFSFEFFPPKDEKGLEELSTTIRELSALNPDFVSVTDSDRGSSKYRHLA
LSKVIKDKTGLNPMLHLTCVNNTRKEITSALENAEELGIENILALRGDMGNFENPGNSDF
SRAEDLVRIIGRTGRFCVGVAGHPEKHPEAATLQEDVENLKRKTDLGGEFIITQLFFDNE
AFFAYRDLIRAEGITVPLVAGIMPVTNLKNFERLLLKTGAIRIPKSLREIMENHKNDKEA
FLKESLAFSAGQCLELLKNGVEAIHFFTFNKSAAAKTIFKELLQARKEPGF
>A0A2X3Y149|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus ferus|TrEMBL
MSKLLDKLKTDILVADGAMGTLLYANGLESCHEYYNLSQPQQILAIHKAYIEAGADIIQT
NTYAAKRHQLKGFGYDGQIKAINQEAVALARQAAGKDVFVLGTIGASRGLRQCDLSLEEI
VSETVEQVNYLLETARIDGLLFETYYDIEELSAVLKAIRPITDLPIIANISLYEAGITEN
GRPLVEAFSQLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFSDNG
ETNQFAFSQNADYFEHCAKLFVEEGVRLIGGCCGTTPDHIKAIKRGIKGLKPIDRKIITP
LMTEEELIKQVQKSETLVDKVKKEVTIIAEIDPPKTLDIDRFVAGVKALDKKGIAAITLA
DNSLARTRICNVSIASLLKEEIDTPFLLHLACRDHNMIGLQSRLLGMHIHGFDHLLAITG
DPSKIGDFPGATSVYDATSFKLLSMIKQLNQGKGYSGASIKQATNFTVAAAFNPNVKNLS
RTGRLIEKKIAAGADYFITQPIFNQNQIDELSQLTKPYEEPFFIGIMPITSYNNAVFLHN
EVPGIDLSEEFLARLEAVKEDKEACQKLALEESKALIDKALEHFNGIYLITPFLRYDLTS
SLIDYIQKRA
>A0A4Y7X1L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalihalobacillus halodurans|TrEMBL
MTNLVEALKTNILVGDGAMGTLLYEQGIDRCFEELNVTDPEKIVAAHVAYVEAGADVIQT
NTYAANRMKLAKYQLDDQVLEINRAAVRLARKAAKQETFVLGTIGGIRSVQFEEVEIQEV
QDVFLEQMKALVSEGVDGLLLETFYDLEEAKLAVSLARSLTDLPVIAHLSIAEIGVLQGG
KLLEEAFAELEGLGADLVGINCRMGPYQMLRSFETVQLLDRAYYSAYPNASLPDYRDGRL
YYHSNPEYFYEMGKRFVQQGVRLLGGCCGTTPEHVRAFAKVVKGLKPVVSKPVRLEIKET
LSSTGQKTAREPLAEKVKKQPSIIVELDPPKNLAIDRFVEGAAALKNAGVDAVTMADNSL
ASPRVDNLALGAIIQQQAGVRPLVHVTCRDRNLIGLQSHLMGLHALGMTDLLAITGDPTK
VGDFPGATSVYDVTSFQLISLIKQLNEGISFSGKELGQKANFSVGAAFNPNVRHLERAVQ
RMEKKIEAGADYFMTQPIYNEKQIEDIYEATKHIEKPIYIGIMPLINGRNAEFLHNEVPG
IKLTDQIRERMAHAGEDRQKGEREGLAIAKSLLDVATHYFNGIYLITPFLRYGMTVELTH
YVKETQHQIRQPERSIQK
>A0A1H1UM57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jiangella sp. DSM 45060|TrEMBL
MTTVLERLAGRRPVFSVEFFPPRDDADETVLWTAVRQLEPLDPAFVSVTYGAGGSSRERT
IRTTGRIRRETTLTPVAHLAGVGHSRAELRNVVGWYAEHGIRNVLAIRGDPPGGPSAEWV
AHPDGVTYADEMVSLIGGLGAFCVGVAAFPHGHPESPDLETDVRRLLGKIRRGAHFAVAQ
LCFEPDYFLRLRDRLAVLGCDVPLLPGVMPLTTRRTLAKSVELSGVSAPAAVAERLARHD
DDPAGFRAEGLDITTSICERLLAEGVQGLHFYTLNRSTATRELVRRLGLGVSDRVHEDAS
RGRRGRPSEAGAGDGPMVGGRLQG
>A0A1G3Q6J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium GWF1_49_6|TrEMBL
MKIRDILRAGKGVAFEFFPPKSEATEASLFEHLKLLEEIDPAYVSVTYGAGGSSRENTRR
IVRRIAEEEKLTVMAHLTCVGHTRAEISGIVADYAECGIENIMALRGDTPKGTDIDPSKG
ELPHASDLIRLIRAEHGDKFSIGGAVFPEKHLESPDLEHDIRALEEKVDAGIEFAVSQMF
FVNKYFYTLLERAEKAGIKIPIVPGIMPFTSYTQIGKIAELSGAEIPKDLVEKLTAAESD
EEIYKIGVDFSIRQCMDLIDHGFEFLHFFTLNKSNATLDIYKAIRSRLE
>A0A0X6ZWZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. LY4|TrEMBL
MLRSETARQNGDIRLSFEFFPPKNPEMETQLWETVAELKKWNPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSHLATAAHLTCVDASREDVHQVIEEFRNAGVRHFVALRGDPSTGIGTAYK
PHPEGYENAAALVKGLREIADFEISVSAYPEKHPESASEEVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYD
DDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A4U0TR85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinomyces thailandica|TrEMBL
MDKITDKIAALPPDANYFSLEFFPPKTQQGFSNLQARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGVRNILALRGDPPRSEE
YRDPNNPLAEEDDSNKDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLPNLVEKTEAGADFIMTQLFFDVEAYIDYEKRLRAHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLKRLEGVKGDDEAVKRAGVNILCEMVEKMRGNKSPCARGFHFYTL
NLEKVVTQILERSSLIPPATPVIRTADGNDVAEQAVAEEESDGFLMVEDAKKNRHRRKSS
ARNSAPQNRVVVVRDRASSTSSSQTQAYEAPEDEAGVPQEPINSRANTLTISEGQGSAGR
EATWDDYPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRNHLEG
KVEAVPWSEEPLQPETLIIKNELLGLINKGWWTVASQPAVPGVRSTDPSFGWGPKNGFVF
QKPFVEFFLPAADWKRLKPILQADEQVTYFAGNAAGEFVCSDEQSVNPVTWGTFTGKEIV
TPTIVEAVSFKSWLEEAFGIWGEWQRVYQPGSESSKLLERVRKDYWLVNIIHHGYLEKGA
LWDALIAA
>A0A1Q7Q1P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium 13_1_40CM_2_68_14|TrEMBL
MRITDMLRFAAERGEPVFSFEFFPPRNDAGVAALFETLRALRPLAPSFVSVTWGAGGSSR
GRTLEMVTRIKRETEIEAMAHLTCVGASRKELEEQLAVICDAGITNVLALRGDPPRGQRE
FIVHPEGLAHATDLVQLAREVADKRGVSLCIGGACYPEGHPETRDLAKDLRHCKQKVEAG
ADFLITQLFFDNRRYFEFLGRARAAGIDVPILPGIMPITNVDQIERFTALCGAHIPAGLS
AALRARRDDPDAALQLGVAYAALQCAYLLRGGAPGAHFYTLNRSTATRAILAALRAQEPW
RDA
>A0A3E1D9H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrotoga sp. LAW|TrEMBL
MTNSKSFSFEFFPPQTQEGANKLASARRQLAILEPAFFSVTFGAGGSTRERTLEAVQQIK
TDGYEAAPHLSCVGSTRENIRTILHTYKNMGIKRIVALRGDLPSGMATSGEFHYANELVS
FIRAETGEHFHIEVAAYPEFHPQAKSPRDDLLNFKRKVMAGANSAITQYFYNADSYFRFV
EECRKLGVTLPIVPGVMPIMKFSQLARFSDLCGAEIPRSIRKILESYGDDNESVQAFGLD
VVTQLCERLLAGGAPGLHFYTLNQSAPSMEIWKRLGL
>A0A4Q2WFK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforamulus aquiferis|TrEMBL
MKISEIYLQKNPVISFEIFPPKSTTPLETIFSTLAELTKLHPDYISVTYGAGGSSRDRTK
EIASRIKNQYGIETMAHLTCVGQSEAEIDQIVKELRQENIENVLALRGDPPADQLDFDFS
TCDFQYAADLVKHIKSQGDICVGAAAYPEGHCNCTRLSDDLYHLKNKVDQGVDFLITQLY
FDNRVFYNFMENARRIGIECPVAAGVLPVLNGKQIKRIISLCGASMPAKLLMMVDKYGDN
NDDMEKAGIEYASNQVQDLLDNGVEGIHLYTMNKPQQITQILRNVGRA
>A0A252EZF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella putrefaciens|TrEMBL
MAFHHAQHSHSLNQSLSELNGDINVSFEFFPPSTPEMEQILWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQKETNLVAAPHLTLVDASDEELLDLAKHYWKSGIRDIVALRGD
LPAGSPKPTRFAADLVRLLRSVADFDISVAAYPEVHPDAANAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVTNFTQLKRFAGMTNVSLPSWLHKQFD
GLENDAGTRQLVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPKAV
>A0A2V9W987|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MASDFLARIKHSPVLCDGAMGTLLYAKGIFINRSYDELNLSHPELIRGIHHDYLQAGAEI
IETNTFGGNSFRLGRHSLADKVRDINRAGVRLAREAAKSFDVWVAGSVGPLGTRIEPLGK
TSFEEAREAFRQQIETLAEGGVDLLILETFGYLEEIHQAMLAARDVSSSLPIVAQVTIDE
DGNCLDGSDPQTFVAKLEEWGADVIGCNCSVGPVAMLDAMERVRAATSLPLSAQPNAGIP
RSVDGRNIYLCSPEYMASYARKFVAAGVRLVGGCCGTTPEHTRVMKSALRAGEAKGKAAS
ARVVGGESAPPQVPALPLESRSLLGARLAKGEFVTMVEIVPPKGIDISKEIEGARFLKSV
GVDAVNIPDSPRASARMSNQALSLLIQREVGMDAILHYTCRDRNVLCIQSDLLGAAAVGI
KNLICITGDPPKMGNYPDATAVFDVDAIGLVNIVHNLNRGLDLGGNPIGSGTGFVIGVGA
NPGLTDLDEEIRRFEYKVEAGAEYAVTQPVFDLRLLENFLRRIEHCRIPVVAGIWPLVSV
RNAEFMKNELRVSVPDAILERMARAQNPEAARAEGVAIAREMLIAARQMTQGAQISAPQG
RYSSAVDVLEALGGDRESTATV
>A0A7V9GCP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKNFSELLDSDSIYVFDGAVGTRFYDKGIYINRSYDELNLVSPDLVREVHDEYIRAGADI
IETNTFGATRYKLQQYGLENQLREINLAGAKLACQAAGQDVFVAGAIGPLDLRIEPYGPT
SFDEAKEMFAEQVSALLDGGVDLFCLETFSDLSEIQQAIKAVKELCDLPIVAQMTIQTDG
KTIFGATPEIFTQRLETWGADIIGVNCGVGPTHILTALEQMRGVSTKKLAAQPNAGLPRD
VQGRQFYMCSPEYMSKFAKRFIKAGANFIGGCCGTTPKHIKLISDAVRAISPRQTRVAVK
PMQPAQVKDVAPTDVQVVPAEERSNWSRKIARGEFVTSVEVLPPKGCDAAKTLEAISSLK
AAGVDAVNIPDGPRAQTRMSAQATAILVEQNLGIEAVLHYCCRDRNLLGMMSDLLGAAAL
DLHNLLIITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNSIGRPTAFSIGV
GVNPGAMNLEEEIRRFEWKVEAGAEYAITQPVYDTKQLREFMEKIAHVKIPIVAGIFPLV
SIRNAEFMHNEVPGVRVTQDILERMRKASDISKEHAREEGLQIARESLTEVRDLINGVQV
SAPFGNVKYALQVFDVLDEFSTKNAGVSQQLRAGLMSDQ
>A0A2V8X0R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
FYEQALALEERGVDFYILETFSYIEELLLAIDAIRSFSGLPIVAQLTYSEEGTTHGDVRP
SDAAVQLKNKNVQVVGSNCTLGPQALLPILQELAAVDDLRVSAMPNAGFPKREGDRIVYP
KSSPEYFALFAREAAALGVRILGGCCDTTHAHIRAMPEAVKSLRPAKTHPAAPAVEMISK
PAPVVQREPESRFWKRLQARKFTVCVEIDPPKGLSLDRIFEQVEKVMASGKVDAIDINSG
AMARVGMDALIVAGALEARGVETVPHLTTRDQNIIGLQALLLGAWTVGGVRNVLAITGDP
PSVGDYPEASGVYEVDSVGLVKVLNRLNQGTDWAGKTLGGATNFTIGVAINPVADDLDTE
IERFQAKVEAGAHFAMTQPLFDPEHWRAFLKKLGGKPAIPVLIGIWPLSSYKQALRLNNE
VPGIVIPEPLLKAMETAGAAARDRGFQVAREMLAWSRTELAGAYLIPPFKRYEEILEIL
>A0A2V8I023|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKPFLAALDERVLVCDGAMGTMLYAKGVFINRCFDSLNVMSADTVTEIHQDYVRAGADVL
ETNTFGANRIKLRSFGLGDKVREINVEGARIAKKAARDQAYVAGAMGPLGVRIEPWGKMG
TDEAEAYFREQAEALVEGGVDLFILETFRDLNEIGAAIAAVRSISKLPIVAQMTIEDDGN
SLDGTPPEQFAPEMQRRGADVVGVNCSIGPAHMLETVERMATVTRARLSAQPNAGRPRDI
EGRNIYLSSPEYLASYARRFAQQGVRLVGGCCGTTPEHIRQMKAAIRQVNVGKLAAKPAA
PGSAGRVLVDSPDSPAPAATPVPRSEKSQFAAALAAGRFATVVELLPPKGFVGDQMIEQA
RALKIRGVDVVNIPDGPRGPRMSALALAVLVQQKAGIETVLQFSCRDRNLLSMQSDLLGA
HAMGIRNLVSVTGKSRMVGDYPDATAVFDVDSVGLTNVITRLNHGLDIGGQPIGTPTGFH
IGVMVNPDADNFDSELRRFEYKVDAGAEFAITRPVFDAATFERLYKRLEAARIPILVGIW
PFENVIDAEFMANEVPGVRVPDHVLERMRGAKDEHEAAAQGIAIARETLLAVRGSVSGVH
IAAPGGHIDAALAVLEGIGVPN
>A0A2V7XTL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKGFLERIQEGVLVCDGAMGTMLYARGVFVNRCFDELNVSNPALVRSVHEEYLEAGADVL
ETNTFGAHRFKLGPHGFEHQVRKINREGARVAREAVQGRALVAGSMGPLGKPLEPLGNIA
FDAAVAAYREQAEGLAEGGVDLFTVETMPSLDQARAAVTAVRAVSTLPIVVSLTFTEEGT
TFYGDKPEDIVRTLEDWDVSVAGANCSQGPQPMLETVQRMAAVAQRLKLSAMPNAGAPAL
VDGRYVYLCTPEYMASYARRFIAAGVTMVGGCCGTTPAHIRNLVRSVRMVQPARQVVAVV
EPAVAREALPPVPREDKSPLARSLGKKFVVSVELDPPKGADAGRIIDRAQYCKENEVDAI
NVADGPRASARMSAQSLCVLMQTRVGVDTILHYTCRDRNLLGIQSDLLGAYALGLRNVLA
ITGDPPKLGDYPDATAVYDVDSIGLIRIMDHLNHGRDLAGNAIGPPLGIHIGCGTDPSKP
DLDKEVRRLEEKVKAGAEYVMTQPIYDPRTVERFLGMIRHLAVPVLIGILPLYSHKNAEF
LHNEVPGMTIPEDIRERMRRAGSGDAAQAEGVRIAQEALLAVRDLVQGAYIMPPFNKVEL
AVRVIDALR
>A0A7C5V0Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MREPVLQRLEKRPLVCDGAMGTMLYAKGVSLNRCFDELNLSSPHLVKEVHVGYVKAGAEL
LETNTFGANRFRLEKFDLADKVREINLAGARLARESAGEDLYVAGAVGPLGLRLEPLGPT
SLEEARAAFREQIEALATGGVDLIIIETMMDLEEAHQALLAAREAASLPVVVQMTVQEDG
STPSGVSPEEFTRQLDEWGADVIGINCGTGPAAVLETLERMAAVTTKKLSAQPNAGLPHS
IDGRTLYLCSPEYMAERAIRFIQAGARIVGGCCGTTPQHIKAIKAAVKSMGPQAARATVE
AAIRPAQALEPLPIEGRSQLAAKLVRGEFPVVVEIVPPKGCDPRREVEGAQYLKSHGIDA
VNIPDGSGATARMSAQTLAVVVQQQAGIEALLHFSCRGRNVLSLQSDLLGAFALGIRNVW
AVTGDPPQFATFPAATAVFDVDAIGLVNVLSNLNRGLDMNGNPLGAQTNFLIGVGLNPNA
LDPDEELRRFEYKVKAGANFGVIRPVFDLERLTGFLRRVEALDVPRIPLLAGIHPLTSYR
HAEFLNNEVPGMSVSKEILDRMRKVDTGDKARAEGLKIAQEMLLEVRDLVQGVQIVAPFS
RYAMAVEVIEVLGERTHKPEAEGAQPAAHDNPRLM
>A0A2V9CR79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MNIADFEQRIQHAVLVADGAMGSMLFEGAGPQRSFEELNVSQPEAVFRVHQAYIEAGAQI
IETNTFGANRSKLSALGLGDQITAINHSGVKIAREAREAAPHEVLIAGSIGPLAIAPEMR
EVPREEMLEIYREQAQALEERGVDLFVLETFSNIEMLMAAIDAVRSFSSLPIVAELTFSE
EGTTLGGTRPAEAAARLAQKNVQVMGVNCRLGPQSLLPILEGYAGGHRALSAMPNVGFPT
RIGDRTVYPRSSPEYFALFAREAAAMGARIVGGCCGTTPEHIRAMAGAVRGLKLAQAVRA
ASVSVATPPEKARVVRRDPESGLWCKLKAGEFAVSVEIDPPKGISLERIFEQVEKITASG
CVDTIDINSGTLARVGMDALMLAGALQARGVETIPHVTTRDQNLIGLQAALLGAWSIGGV
RNFLAITGDPPSMGDHPETSGVYEIDSIGLVKVASRLNQGTDWAGKALGGATNYTVGVAV
NPAAEDLDYEIQRFLAKVQAGAHFAMTQPLFDPEHWHVFLQRIGGRSPIPVLAGIWPLTS
YKQALRLNNEVPGIFIPESVLKELQSAGTAARDRGFALARRMLAWARTELAGAYLIPPFK
RYEEVLELFT
>A0A832LVJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldimicrobium thiodismutans|TrEMBL
MPKNGFRHILKNEEFVFTFELVPGRSVRTRQYQAILKFLEESTKYNYFQAFSITDNAGGH
PALSPIPLGKTIKELGMEPIIHFSCKDKNRNQIESELLALDREGLHNLLILTGDYPFYGY
QGRAKPVYDLDSVQLLQMITDMERGIQLPKEAPGGGITLPAIPFFKGAVVNPFKVTLSEL
WWQYIKLYKKLRAGAYFIITQVGFIPKKWFELRELLNIGITKVLSQFLEDRNFLNEEEDS
YFQKIPLLGSVLFLTPSLIKALTKGRIPGILITETLVSRYREVEDFEGLSVDICAKLSAI
LKGLGFKGVHLCGFPLDYGVISRFLDKFYTYERDWEALLKEFDDEKALLELPKGTISAQI
PCLLTNGLTLEYKGNRKFFYLFNELFHNLFFNQKSKLYPSLKRLAQRIDKNFWLKKVFTT
FEYLVKKLLFNCQECGDCTLWEFNYSCPHSQCAKYLLNGPCGGSLWGYCEVYPFYKRCHF
VTAFERAPHKENLRKFLRTNERPFLPPRNWALYKSSSWLNFYLERDHQAK
>A0A1H6BFR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halpernia humi|TrEMBL
MKITEHINNSKDKTIFSFEILPPLKGQNIQSIFDAIDPLMEYDPKFIDVTYHREEYDYIE
RGDGLLEKRVVRKRPGTVGICAAIQNKYHVDAVPHILCGGFTKEDTENFLIEIDFLGIEN
VVALRGDAVKTETYFRPEKDGHAFTKDLVKQIKAMNSGEYLDETLQNSSCTNFDIGVGGY
PEKHMEAASFEQDLYHLKKKVEAGADYIITQMFFDNQKYYDFVDSCRAIGITVPIIPGLK
PLVTKSQLSMIPHRFKVDLPNDLVIAIAKSKDNKEAKEIGIEWCIEQSKDLLKNKVPVLH
YYSMGKSANLERVLKAAF
>A0A075KIE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelosinus sp. UFO1|TrEMBL
MKLCDLFDREKPLVSFEIFPPKQTVTLESIFKTTEGLQTLNPDFISITYGAGGSASDRTL
ETADKVKNTYHVEALAHLTCINSQKDDIDTVLNQLQAHNIQNILAMRGDYPLDKGSLKKM
TTTFPYAKNLIAHIKSQHDFCIAAAAYPEGHLECPNLAEDTVHLKEKVDSGTDFLITQIF
FDNAVLYNFLDRIRQANITVPVCAGIMPLLNSRQVARIHSLCGASIPKPLQSIIEKYQNS
PNDFEKAGIEYACNQITDLIAHKVDGIHLYTMNKLEQSKTIIQETGLR
>A0A2V8JMD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSLLKSLLNSKRFLLNVEMCPPRMDLPLEQSIEAWIDSNHLMRKVTSLGRFVFMTDGAIG
RREEPNLRHVTINLGSEAERARIIPILTTKHSLEYCLEFAKRSYLLGFTSLVVLGGDKSD
DTPRCVEHAYELRRLIRQAVPGMTLGGWASPHGGRRQVEFLLYPEYSADFYMAQIVSHYQ
SQSIDEFLNETVRLGVKIPGIFGVFYYRSPNSNTLALLSKFFPVPIEELKKDFEANQSPD
EICALSVHALFRRGLKNVYISNLPTATGAERLSRMEARVQEMLVVS
>A0A523DAN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKFPDFYASGDPVVSFELFPPHSDLGMDTLEERLPKLIALKPSFLTVTYGALGTTRDRTL
QVVSEIRNTYGKEVAHHLTCVGSTREEIGQLLHDIRKENIENIVALRGDPPQGETEFKPL
KGGYRYGNELVEHIREFGGFGIAVAGYPEKHIEAPDFETDLNHLKRKVDAGADLIITQLF
YENRFFYDFVARCRAVGIKQPIVPGLLPILNGEQIKRITRMCGSSIPTELLRKLTQAGDD
RKKVHEIGIRHTVAQAQDLLAHGVAGIHFYVLNQYFHIAEIMEQIQPALQHSTVKKY
>A0A2V8IMZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MARNPLRECLQSRRFCHVVEIVASRISREARLLEVASQLATPPGVVAGSITSYAGGAPGQ
DPVRVGTAARARGLTPNIHVTCVSKDRQELRHYLETIAGLGLENVFALTGDYPTGANAVF
DLDSVQLITLMNELRRQGLPFWIAAAVSPFKYTEPDCAYQYLKLEKKFTAGADYAITQLG
FDVRKFRELRRYLDERNIQNPVLGNVYVLGLKSAEKMSKGEPPGCWVAPELVEKIRDEVK
AKDKGEAARLERAARMIAILRGLGYAGAYIGGTHNAEHLSWIIERGQILAPRWKELADEF
TYAPKSAFYMFEPGPAAPRKLQGLSDRAVNALWHLLSPTQIPRGSILEKWARAMFAWIDR
RPTMSRFLERAEFAIKSPAFGCETCGNCVLPDMQYVCPQT
>A0A523EAP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRSSKRSFVSRQPPHVSFEFFPPKTPAGWDKLKETAAHLAEFEPDFTSVTFGAGGSGNFR
TLEACLAVRSVLAADVVPHLSCIGQTRDSIEAHLAEFRDAGFTRILALRGDVPIDAESAE
ISFPQGGFHYASELVSFIKSRGNFHILVGCYPEGHPEAPSLQTDIDNFIRKVEAGADAAI
TQYFFNNAGYFHFVDEVRRRGLDIPIVVGLMPIWPYEQVVRFSAKCGADVPLWIQKRMEG
YKDDPESQFEFAVEVAVTQSEELLRNGAPGVHFYTLNRPEATVRICENLRGQKIERGPAS
DDVAYGDVEVPASLS
>A0A1Q9UWD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serinicoccus sp. CNJ-927|TrEMBL
MGNTYPSVVLERLLRGARLEILPTASVADQVHGHVEPGRSLSVTASPAKGLEATLQLAEQ
LAGAYHVIPHLAARMVERAALPDLVARLTEAGITEIFVPGGDAEPTDQTFTSALDLLIEL
DSLGSPFTGVGITGYPESHPGIDDDVIVQSMWDKRRYATAVVSNMTFDDDRVGQWLERVR
RRGVELPVWVGVPGPVDPARLLRMASTIGVGDSMRFLRKQRSVFTRMVMPGFSTTRFAHR
MAVLGTADRLGIAGLHLYTFNQVAQTEAWRRTQLSKVAELRDPAAGP
>A0A545AJS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptosporangium phraense|TrEMBL
MATGVSVRRTSVGDLVRDDAPTYSFEFFPPKTDAGEKQLWQAIRELEALQPSFVSITYGA
GGSSRDRTVGITERIATETTLLPMAHLTAVNHSVAELRNVIGHYAAAGVHDVLVLRGDPP
GDPQADWIAHPEGYSYASELVSLVRNSGDFCVGVAAFPEKHPRSPDLESDVRFFVDKCRA
GADFAITQFFFDWQDWARLRDAVAAAGCDVPIVPGVMPVTNVSQIERMAILSGAAFPSDL
ADRLRAVADDQNAVREIGVEVATTLSARLLAEGAPGIHFITLNRSASTREVWANLAPAQV
AVR
>A0A2K9DT51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hominis|TrEMBL
MTVQLRLRDASRRCPKRMVYGPCGGVGADGGCEVPGIRCSFAADPDLLHTLDVSAADVAA
PESAEPSGDALPLSPRRTAAAAFATRVSEGLLVTADLPVRSADAGVLAEAGARLAGLTAV
IAGEPPGLRASLSPTHKALVLGGAGATVIAGITCRDRNRVAIEGELAALADLGVAGVLAV
TGDHPASTALPHAQPVFDLDSTRVAALARRAGLFVAVAEQPAAPPIDYRPVRLALKARAG
AELAILNLCGDLSDLVRFAGALAATGAAIPLVASVPVITSRSAALRLAALPGVRLPSGLV
TAVTAAAAVDDAGVHAAVAAAREALTVPGVVGVHLSAVVDEADPTGLAAVDAIVRTATLL
RAGRAPSSDATATGAAA
>A0A134DJ06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hominis|TrEMBL
MVYGPCGGVGADGGCEVPGIRCSFAADPDLLHTLDVSAADVAAPESAEPSGDALPLSPRR
TAAAAFATRVSEGLLVTADLPVRSADAGVLAEAGARLAGLTAVIAGEPPGLRASLSPTHK
ALVLGGAGATVIAGITCRDRNRVAIEGELAALADLGVAGVLAVTGDHPASTALPHEAPVF
DLDSTRVAALARRAGLFVAVAEQPAAPPIDYRPVRLALKARAGAELAILNLCGDLSDLVR
FAGALAATGAAIPLVASVPVITSRSAALRLAALPGVRLPSGLVTAVTAAAAVDGFGVHAA
VAAAREALTVPGVVGVHLSAVVDEADPTGLAAVDAIVRTATLLRAGRAPSSDATATGAAA
>A0A2N2UDV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-15|TrEMBL
MALPVSFEFFPPKTPEGAEKLRAVRQQLYGQKPEFCSVTYGAGGSTQQGTFDTVGAILAE
GVDAASHFSCIGATKASVREQLTTLKAMGVKRLVALRGDLPSGYGIGGEFHYASDLVAFI
RAETGRDFHIEVAAYPEVHPQAKSPESDLQAFATKVRAGADSAITQYFFNSDAYFRFVDE
AHRLGVDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDIASIKAFGLDVV
TDLCDQLRNAGVPALHFYTMNQSVATLEIVKRLELG
>V2XTY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moniliophthora roreri (strain MCA 2997)|TrEMBL
MKLSEKISTYPSSHPFYTFEFFPPRTDQGFENLLPRIARLSKLSPLAISITWGAGGSTKD
RSLDLASMTQGEGTETILHLTCTNMMQGMVDDALRAAKDRGIQNVLALRGDPPRGKEEWI
PIDPRFQHGVDLVSYIRSKGEFKDHFCIGVAAYPDGHPDKLVSPEAELDSLKAKVDAGAD
FIITQLFYDTENFLEWVKKVRERGITLPIIPGIMPIQTYSSFLRLVKLCGSSVPSKILED
LEVIKYDDQLVKDYGVQLAISMIQHIAQSDAGVKGVHFCTLNLEKSVTRVLEGLQWTGTR
PYAYHHNRLIESSTDLTEHTINPSTALSTALSGTREIPKSQHEAGTGELNNADSWDDFPN
GRFGDHKSPAWALGEGDLWGNLGLIITNKTLESWGPPQTPDDLTNLFLKHLRGKIHTTPF
SPSPLSAESQSILPYLEKLTRKGLWTVGSQPAVDGIHSDDPIVGWGPRGGYVYQKAFVEF
FCDADGVDEIEKKVEEKGGGWVSWFAGSFSGEIRSNMPEDGRNAVTWGVFPGQEIVQTTT
IEKEGFGSWKEEAFSIWLKWASYYPPQSAERALLDKVRREKWLVSVVHHDYKDKDALWEF
LFDD
>A0A1B1NE79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serinicoccus hydrothermalis|TrEMBL
MMGNTYPSVVLERLLRGARLEILPTASVADQVYAHVEPGRTLTVTASPAKGLEATLALTE
ELAAYYHVVPHLAARMVERAALPDLVARLSAAGITEIFVPGGDAEPTEETFSSALDLLIE
LDAMGSPFSGVGITGYPESHPGIDDDVVVQSMWDKRRYATSVVSNMSFDDDLVGQWLERV
RRRGVELPVWVGVPGPVDPAKLLRMASTIGVGDSMRFLRKQRGVFTRMVMPGFSTTRFAH
RMAVLGTADRLGIAGLHLYTFNQIAQTEGWRRTQLSKVAELRDPAAGT
>A0A6C8GWH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Uganda str. R8-3404|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0Q8SM97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. Root219|TrEMBL
MNAAKAQATGFPVSLEFFPTKTQAGADKLRAERQQLYALSPEFCSVTYGAGGSTQEGTFG
AVREILAEGVPAASHFSCIGATRESVRQELAQLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFHIEVAAYPEVHPQARSPEADLKAYLAKVQAGADAAITQYFYNAD
AYFRFVDDVQRLGASIPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASI
KAFGLDVVTDLCDKLRSEGVPALHFYTMNQSAATLEICRRLVL
>L1PLQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 324 str. F0483|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKVDAGADYVVTQMFFDNQKYFEFVEKAKEAGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEELIKAVESCKNNNEVKQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A409WGA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psilocybe cyanescens|TrEMBL
MKLADKIQAHNALNPFFTFEFFPPRTDQGFENLMSRISRLSTLNPLAISVTWGAGGSTKD
RSLELAGLAQNGDLDTILHLTCTNMEMGLIDQVLKSAKDQGIQNILALRGDPPRGEEEWT
ASDPRFSRAIDLVSYIRSIPEYSSWFCVGVAGYPDGHVDNPVDEDTEVIRLKEKVDAGAD
FIITQLFYDIDHFLSWYKKVKEKGITVPVIPGIMPIQTYSSFSRVTKLCGAHVPESVSMA
LAAINQDDRLIKDYGVNLATETIRRLSYEAGIKGFHFCTLNLEKSVQRVLENLGWAGSLS
SVQNKLIVVCPFSEIQFITTHSYFSKDPPSNRPSPEVDSNLIISPSNATNSAMFGLSTLS
TSEGEAGQGELNNAATWDDFPNGRFGDFKSPAFGNQDLYGGSGISKNEALALWGNPKSAS
DLTQIFLDYLHSKIPTTPFSPTTLSPESRMIFSHLENLTRRAWWTVGSQPAVDGANSSDD
VVGWGPNSGYVFQKCFVEFFCGATDVEAIERKIEEKGNGWVHYFAGNHKGDWRTNVPDNG
RNAVTWGVFPGQEIAQTTIIESESFLSWKDEAFSIWSEWASFYRPGSDERKLLEDVRDNQ
WLVSVVHHDYKNREALWTFLLDD
>A0A134DI65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium hominis|TrEMBL
MRPAADRLNDPDPRANRAMMSHEPRATAPIVDDVSPRSARTVPFSFEIYPPRTAEGLPAL
HETIRVLAATGPRFISVTFGAGGSTTDRSLAVLTHILRETPVPPVAHLTCVGSSYAEAAT
VIREFLDAGITRFLALRGDPPAGVAEDEVALGDLESAAQLVQLIDRVQAERSPYREQEIP
GVPGAAPVAAGERVEIAVAAFPNGHPRSRHRFEDIDALLAKQAAGATSAITQLFFRSADY
LDFVSRARAAGVVIPILPGIMPITSPARLRRVLELTGDPRPDDLAVALEAATDANGQRAV
GIAHAADLARAVLDGGAPGIHLYAFNNHDTVLAVLRAAGLIPEETTP
>A0A5J4XL51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trebouxia sp. A1-2|TrEMBL
MKVVDKMNAAQKAGELFFSFEFFPPRTEEGVENLFDRMDRMATHDPTFCDITWGAGGTTA
DLTLEIAGKMQNMVCVETMMHLTCTNMPQDKLREALDKIGFRENYGDYFGITVAGYPEAH
PEVITDDAEEMERAYQSDLQYLKQKVDAGAQVIITQLFYDVEKFIKFTQDCRALGIECPI
IPGVMPIMTYGGFKRMTGFCKTHVPKDVEAALESIKDNDEAVKNFGIDLGTRMCKRILDS
GTPGLHMYTLNTERSSVAILENLGLINKSQAGLLLLNRSLPWRQPTNERRKAEQVRPIFW
ANRPKSYINRTSDWDKYPQGRWGNAKSPAYGTLNDYQFMRRHTNSSKRQEKAKQCWGASL
SKIDDVNKVFVKYAQGDLGMLPWSEMEGFHRETGTIQSQLQQLNTQGYLTINSQPQVNGA
PSTDAKVGWGGPDGYVYQKAYVEFFISPEKLENLEQRLQKQSSITYMAIDSKGKVRSNVG
QSDVNAVTWGVFPGKEVVQPTVVDPHSFSVWKDEAFQLWTEDWANLYEKNSRSYKIIQDI
VDHWFLVSVVENDYVHGDLFKVLLGTTSKDDQVEEVAAAWNPASQQQQPEPKEALKAAAA
H
>W8RVT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibacterium elongatum DSM 19469|TrEMBL
MALLSFRSPTARAHPVTRASGSLEALLQGYSIEVMPRTADKVADFRALLPAGTRIYIAHI
DGTPIEDMVHTARRLARDGFEVMPHFPARSIPDAQTLSDWIARYQDEANVTEGLILAGGI
PETRGRFHCSMQLLETGLFDKAGFKRLHVAGHPEGNRDIDPKGGDRAVMDALRWKQAFSE
RTDAKMALATQFAFDAGPVIAWAERLRAEGIDLPIHLGIAGPAKLQTLIKFAIACGVGPS
LGVLQRRARDVTKLVKPMEPTEILRALAAHKAAHPDSLIERIHFFPLGGIRTNAEWAIAN
GGPSAQPANTHPESTA
>A0A2K1DTE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio agarivorans|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKHLQPKFVSVTY
GANSGERDRTHSIIKDIKAATGLVAAPHLTCIDATREELNAIADDYWFNGIKNIVALRGD
IPPGGGAPDMYASDLVELLKARHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFE
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVVLEV
>A0A7D3UZZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas hydrophila|TrEMBL
MGFHSARQVEALNQSLADLSGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPQGLEKPEMYATDLVALLKAEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLDDDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQS
>A0A8J7FFG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinilyticum piscinae|TrEMBL
MRPPISFEFFPAKTAEGAIKLQTTCQQLAQFNPEFFSVTFGAGGSTQEGTLKAVLDIRAA
GYAAAPHLSCIGATRERLRALVQNYQDHGIRHIVALRGDIPSGMVELGDFRYANELVSFL
RAEFGDWFHIEVAAYPEFHPQAVSAEADISNFVNKVNAGADAAITQYFFNADAYFRFCDA
VQARGVTIPVVPGIMPIQNFSQLARFSDVCGAEIPRWLRLRLQAMGDDVASIRAFGLDVV
TELADRLLAGGAPGLHFYTLNSAGAVSTICQRLGY
>A0A7Z8GPJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mammaliicoccus sciuri|TrEMBL
MSLKEALKNQILLADGAIGTILYSEGLDTCPESYNLTHPNKIEQIHRSYIEAGADIIQTN
TYGANFEKLQDFNLEHRVKEIHREAVQIAKRASNDHTFILGTVGGFRNIKKSNLSIEAIQ
YHTEIQIETLVNEGVDGILFETYYDLEELLAVLKDTKARYDIPIIAQLTASNTNYLRNGT
PIPDALETLVKAGADVVGLNCHHGPYHMIKTFKHIDLPDHAYLSCYPNASLLDLEDNDLK
YNNNSDYFSDAAKELVNQGVRLIGGCCGTTPEHIKKIKNVVKDLKPIKHKNVIPIETKQY
KKQNKEEPSIKELVQQRPTVIVELDTPKHLDTNKFFDGIQALEDAGVDAVTLADNSLASV
RISNIAAASVIKQKYKIRPLVHLACRDRNLIGLQSHLMGLSLLGINDILTITGDPSKVGN
FPGATSVFDVNSSGLAEIITQFNQGINADGDTLRSNTNFSVAGAFNPNVRRLEPAVKRLE
KKIESGMEYFITQPIYEPERVKEIYEATKHIDAPIFIGIMPITNYNNALFLHNEVPGIKL
SDTVLNAFEKVKDDRDATRELSINLSKQLIDAVHQYFNGLYLVTPFLKYDLTVELANYSQ
LKTGTQTKEAIL
>A0A7Y7T222|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. D2002|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVAAAPHLSCVGDSKADLRGLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLHNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1U6IM55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium mathurense|TrEMBL
MTDETEAKGADAQRDRPIVHPAWLHPHDTLIEGYSLEVTAKDIEALTNAASTIWAGAPIA
VPYLPNESHEARVAAAKAVRDLGFEPMPHFSARRIGSHDEFVRFLGDAVKVAGVERCFVV
AGDPSTPEGPFTDSMTMIETGAFESAGIKVIGIGGHPEGHPVMSEEECWQALETKCAAIE
ARGMAPLIVTQFAFDAEVILRWLKALRVRGLDHPVRIGVPGPAGIKTLARFAAMCGVGAS
ASVLAKYGISLGRLIGPAGPEKFLDALGRDLGPEHGAVRLHFYPFGGVAKTVDWITAYAA
R
>A0A011T960|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella anthropi|TrEMBL
MGFYGLSRRPDIGQTTRVSFEFFPPKSEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDVKPAAHLTCVDATREEVDRVVREFAALGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCTRSATHIPSWLAERFE
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTEAAL
EVA
>A0A1F3EA13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWC2_33_15|TrEMBL
MKVIDTIKKSKSALFTFELLPPLKGHTIQEIYDTIDPLIEFNPAYINITYHQQEVIYKTR
TDGFLEKRVIRKRPGTVAIAAAIQNKYKITVVPHMICGGFTKEETEDALIDFHFLGINNL
LVLRGDPLKGARLFIAEKGGHSHSSELIEQIMNLNKGKYLNEDLIDAMPTDFSVGVAGYP
EKHVEAPNIDMDLEYLKLKVDKGAEYIVTQMFFENQTFYRFVDKCRKIEINVPIIPGIKP
VSTLNDIALLPQTFHIDLPNDLIREIKKCKTNKDVRQVGVEWATNQSKELIKSGVPGIHY
YTLDQSDNIKKIAQAIF
>A0A1J5NP37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorella thermoacetica|TrEMBL
MVESKIAKILSKGQFLVSGEIGPPKHADPSEIKKHATLLKDYVDAMNLTDNQTAIVRLSS
IAAGVHVLQAGGEPIIQMTVRDRNRIAIQSDLLGAYSLGMRNILCLSGDHQSFGNHPTAK
NVHDVDSLQLIRIVKDLRDEKKFACGEEIKGQEPRFFIGAAANPFADPFEFRVMRLEKKI
NAGADFIQTQCIFDMERFERFMALVRERGLHKRAKIIAGVTPLKSARAAKYMQQSVAGMI
VPDEIINRLEKASDPKAEGVAICVEQIKHLRTIEGVAGVHIMAVMWEDIIPTIVKEAGLY
PRPKVE
>A0A6L5XTR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. WCA1-178-WT-3|TrEMBL
MRVDEVFKQAASQGTTPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENVLALRGDLPASAN
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACENLNLSVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMTFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGADGLHLYTMNRPAIAATIMERLG
>A0A7C5GAZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliiroseovarius sp|TrEMBL
MKTPRISFEFFPPQTLDASFRLWDTVRTLAPLDPSFVSVTYGAGGTTRKLTHEAVGTIHR
HYGLNVAAHLTCVDATRAETIEIAREYKKVGVNGIVALRGGPPKGSAGCAPHPEGFASSV
ELIEGLAREGGFHIRVGAYPDPHPESSSLADNVAWLKRKVDAGANSAITQFFFEADTFFR
FRDACVAAGIDVPIIPGLLPIENWGGVRKFADRCGAHVPSWLDDAFAKAARDERQELLAV
SLATELASDLIEGGVEDIHFYTLNKPHLTRDIAHALGITAKSDLSQVA
>A0A857HFM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis|TrEMBL
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTRAKEFIS
VHHERTEPGLDEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALIKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMAHAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>A0A6A6NK55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hevea brasiliensis|TrEMBL
MATTLALLSLVIQVLKAILGFLLCPILLHYPQKIISLCSSVIFLSEAHPDMIGSDGVATP
ENYQKDLEYLKRKVDAGADLIITQLFYGIDIFLEFVNDCRQIGINCPIVPRIMAINNYKG
FLQMTSFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEVCKKILAHGIKTLHLYTLNM
EKSALAILMNLGLIDESKITRSLPWRRPTNVFVQRKMFVQYFGLIVPRATYQEP
>A0A1H3Y1S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloplanus vescus|TrEMBL
MTLTHADATSLLREPRFELMPFDSFEGQMEQLPDGAEIAVTASPQLGLDATVEWSERAAA
RGYEPIPHVAARYVRDRDHLDEVATRLADAGIADIFVPGGDREEPLGEFESAYDLLTALD
DLGHEFAEVGITGYPEGHEFLEDDTLAAAMERKAPHATYLTTQLCYDPDAIAEWIETVRD
RGIDLPVEVGIPGVMKYQRLLNISQKVGVGDSVRFLRKTSGVLGFVRQLVGSRGKYTPDG
LVDGLAPYATDPEYGIRGLHIYTFNQVGDTEAWRRDRLGER
>A0A1W9PEG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium 4484_219|TrEMBL
MGKSFREHLEQDEVLVCDGAMGTMLYSKGIYINRCFDELNLSNPAMVKDVHLDYLKSGAD
IIETNTFGANWFKLEPHGLEERLYEINFQGVKIAREAAGDKAFVAGSIGPLGRPIEPIGH
LSQEEARQAFYDQAKAQFEGGVDLFILETFKDINEIHQALLAVKDVCDLPVIAQMAFTDE
GKTAYGVSPEEVVRKLEGWGADVVGINCSTGPEGVWKAIQEMARVSDIPLSAQPNAGFPQ
LVQGRLLYLASPEYFAEYAKRFIQSGVRIVGGCCGTTPAHIRAIRTAVKALRPSRQLVEV
KVVEVEEKVLQVKKPAEKSKLGEKLGKKFVVSIEMNPPRGPDFSKVVEGARRIKVAGVDA
VNIPDGPRASARMSPLALATILESKVGIETILHYTCRDRNILGMQSDLLGAHALGLRNIL
IVTGDPPKLGDYPTATAVFDVDSIGLVRIANNLNNGTDLAGNPIGAATSFHIGVGANPGA
ISFEEEISRLKQKIEAGAEYILTQPVFDIKLLEKLLDGIKEYKIPVLAGILPLVSYRNAE
FLHNEVPGMSIPKTVRDRMQRADSGEEAKKVGVQIAQEVLQEVKNMVQGVYLMPPFGRYE
VALQVVEVLK
>C0QE80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforapulum autotrophicum (strain ATCC 43914 / DSM 3382 / VKM B-1955 / HRM2)|TrEMBL
MLRIFSEELMNPDNFVITIELVPGRESFGRNTDTLIGIAKDAFSDGRVSAVSITDNPGGN
PSLSPDVLGYEIFRHGLDVIVHFTCRDMNRVGMESRALQLARMGMKNILCLTGDYSGKGF
GGRGAPVFDLDSVLLTRMVKGLSNRMMTSGDPDPFFSGCGVSPFKTLKSECLAQYKKLDM
KIDAGASFAITQLGYDINKFNELIRYHNEKNAHIPVMASVFLLSPKAARAMNKHRVPGAH
VSDALYEKVTQEWKIPKEGLNAAIERSARLGAILKGIGFRGIHIGGVHRSFTTVARILDR
MEKIGDDWPAHMNEFSGKEKNAYYVYDKIVEDKNIPAFKPGLKERVINHWPYGMLCFAHN
LFFNKTAGLAPVYRKLAAFLESHDKEWVLKHCLEDPIKIPLLSCQSCGDCGIQHTAFLCP
ESGCPKHTRNGPCGGSRNGACEVYPDKECIWVRAYKRLDYAGKLSTFLEDKVPPRNWELN
KTSSWINFHLNRDHQKEKKQIKQQP
>A0A1E7G4A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris IBB477|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYLAKNQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>A0A366SEQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus cecorum|TrEMBL
MREKHWRILQEAQIKAIPSNDFSLYDQTLDTAFLLNIISTEVANLDLSPLEKYFALALGY
QGAKGDVKARPMKKWFNTNYHYLVPKFEKNTQIKVPRKFMAILEKYEYQPESLKEAGLAY
ALDQIVDLVTQDAEGIHLYTMNQAETARYIYQATTAIFQNLSHAS
>A0A447CXD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoplanes piscinae|TrEMBL
MSPPTEPRQSRVSHERNGMRVSFEFFPPKSDEMERTLWESIERLAPLRPHFVSVTYGAGG
STRERTHATVKRILDATPLTPAAHLTCVAATRDEVDDVVRSYVVAGVRHIVALRGDPVGG
LGTAYAPHPGGYLNGADLVGGIKRLAAVEHADIEVSVSAYPERHPESPSDAVDLDMLAAK
VDAGASRAITQFFFDNDLYFRYLDRVRARGITIPIVPGILPVQNFKQTRVFAERAGASIP
SWLADRFAGLDDDPATRKLIAAAVAAEQVFDLVDRGVTEFHFYTMNRADLVYAVCHLLGL
RPVASPASAGAAATAEAAA
>A0A4R5YIJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium oleivorans|TrEMBL
MSIIQTPSVTTVPVSFEVYPPRSDASDAALHRTIARLAEVEPSFISVTYGAGGSTAGRSL
EVLRHIRRETRVEPLAHLTCVGNSYREATALIREFLDAGIRSFLALRGDAPQGAPEDPDG
AGDLESAAQLVQLIDRVQAECSPYTEEPIPGVPGAARVERRRHVDIAVAAFPNGHPRSRY
PAEHIDALLAKQAAGATLAITQLFFHADDYLAFVSRARAAGVVIPILPGIMPTTSPSRLA
RIVELTGQPVPGALAVDLDVEPTAEGRREVGVRYAAGLCRAVLEGGAPGIHLYAFNHHRT
VLATLAEAGVITPTEETS
>A0A1F4U5G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-1 bacterium RIFOXYC2_FULL_46_14|TrEMBL
MKVIDALKRDKQTLSFEFFPPKTEEQEKKLFEVIGKLKEYNPDFVSVTCGALGTTRDKTT
FWTKEIKDKFHITPVAHLTCVAEPRDHIKVHLDQLDKIGVNNVLALRGDPPQGHSRFVPA
LKGCRYAKELVALIKKEKPDFCVGVAGYPEGHREAENIEKDTEYLKQKVEAGAEYIITQL
FFEAELFLKFEERCRKAGITVPILPGIMIINSFKQITKMTELCGASIPDEIMRQINRHQG
DQSAIEKIGIEEASKLCARLKQEGIPGLHFFVLNQAGPIAVVLQQLSL
>A0A1V6TYV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium steckii|TrEMBL
MHIREKLAQKEAAGEPGISFEFFPPKTAQGVQNLYDRMDRMANLGPGFIDITWGAGGRLS
DLTCEMVGVAQSVYGLETCMHLTCTDMGREKVDRALQAAYKAGCTNILALRGDPPRDKET
WEATEDGFRYAKDLVKYIREKYGNHFDIGVAGYPEGADDNPDVDLLIDHLKEKVDAGGSF
VITQMFYDAENFIAWVKKCRDKGITIPIIPGIMPIQTYAAFIRRSNWTKTRVPPEWLEAL
EPVKNDDAAVRDIGKHLIAEMCRKLMASGINHLHFYTMNLAQATRLVLEELGLAPSDESP
IQRQLPWRPSLALGRRGEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDLSEIFISFLEGKLDRLPWSDSPITAEASDIHDLLMN
VNRRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSNLIDQLITKIEKND
DLTYHATKKTGELKTNTRDSPNALTWGIFAGREIIQPTIVETISFLAWKDEAYALGDDWA
KCHDAASPSRKLIQQVMDDWWLVNIVDNDFHRTSAVFDLFNDLEIKDFAVELPSKPETNG
TSEQNGTAAKN
>A0A0M2XQG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium xerosis|TrEMBL
MSDFPPPAVGRQVPVRHALTLPSPGPVPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFA
SVTYGAGGSSRDRTLRIAERVSREPLTTLVHLTLVGHTVPELREILRAYLDRGLTNLLVL
RGDPPGDPLGDWTPMEDGLSYASELIEFIRSEEEFADFEIGIASFPEGYFRAPDLESDTR
YTLAKLRAGAEYSITQMFFDVDHYLRLRDRLAAADPEHGSKPIIPGLMPITSMRSVRRQL
ELSGSVLPAALDERLTRAAAGDEEANRDEIRKVGIEVTTEMAERLISEGVPGIHFMTLNF
ARATQEVLHNLGMAPAWGTGQDMLRGGF
>A0A0Q0X321|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonlabens sp. YIK11|TrEMBL
MKITDHIKQADQALFSFEIIPPVKGKSIQELYNNIDPLMEFKPPFIDVTTSREEFIYIEK
KGGLLEKKLTRMRPGTLGICAAIQNKYDVDTVPHLLCGGFTQQETEYLLVDCQYLEIDNV
MALRGDARKEEKRFESTDGGHKYAIDLVKQINDLNKGHYLHDVIEISCDVDFCIGVAGYP
EKHEESPSMKTDLKRLKDKVEAGAHYVVTQMFFDNQKYFDFVKAARDIGITIPIIPGIKP
IATKAHLQLLPKTFHLDIPQDLVDAVENCKTNKDVRQVGVEFCVEQCRELLAHDVPVLHF
YSMGKSDNIYDIAKAIF
>A0A1F9L640|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYD12_FULL_56_24|TrEMBL
MLVKDILDNNRFSFSFEFFPPKDEPGWESLFANISDLMPLKPAYVSVTYGAGGSTRDRTH
KLIVRIQQETSLTVVSHLTCVGANREETAEILSSYAASGVENILALRGDPPKGQTDFVQP
RDGFAYAADLVAFIKKNFPQMGVGVAGFPEGHPGTPNRLLEMDYLKAKVDAGADYIVTQL
FFDNRDFYDFRDRCALAGITVPIIAGLMPIASRSGMVRMAELAAGARIPAPLLRALERTR
NDEQVEKVGVHWATEQVRDLLDNEVLGIHFYTLNNSRQALDIYQTLGVDDSLQLGA
>X6HPD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. L2C067A000|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTIKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A3E1B6T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum bv. trifolii|TrEMBL
MTIAPQSEIREKAPLADLLSHYSIEVTSRDLSSLQSMTATLRPGSEVFIAHLPKEDIGLL
VRAAAGLRDAGFVPVPHIVARNIRNRLELDTMLARLSEEAGVRHALVLGGDRDDAAGAFG
SALDLIETGLFQTYGVGRIAIACYPEGHPRIAGAVLDTALTAKVDAAARAGLDVLLVSQF
LFDPQPLLSFARRLRERGVAAPLRVGIAGPASRTKLLKYALRCGVGASLRALREGSEIAR
NVLSGETPEELLIDIAAAQAAEPDLGIGGAHFFTFGDPAQSIRWAEQQAASD
>A0A5C7FWI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia arenae|TrEMBL
METPDFSIEFFPPKTPEGAEKLRIARAKLADLNPKYFSVTFGAGGSTQQGTLATVREIQA
AGHEAAPHLSCIGATRESIRDVLKQYQDSGIKRVVALRGDLPSGYGGAGELRYASELVEF
IRQETGDWFHIEVAAYPEMHPQARSPQDDLQAFARKVGAGANAAITQYFYNADAYFQFVD
NVRKLGVDVPVVAGIMPITNYMQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTAIWQRLRA
>A0A545SHU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp|TrEMBL
MFDTFCSKLHSDKPFITVEITPPHGSSMDKIIASIEDIGLHKKVAGFSVTDNPLAKLKMS
AILSAIKVQQHFNLPVIATMSMRDRNKLSLQSSILGANDFDLRCILALTGDPAKFSDQPE
VKGVLERDSTLLLSIIYKLNQGLDYSNKALNPAPKPIYPFAVSNSYAKDMKNIQKKMIKK
LNYGARAIITQPVYDLANAKKLIEIFEEAKEISIRESAKEAQLILGQFPVVRAKTANFIA
DKVPGISVPKEIIDEMNLASMDGEAKEQEVGFALSKAIFDEILTNHGKIHLMTHNRFDLC
ADLIKGVN
>A0A4Y6S2H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Labrenzia sp. PHM005|TrEMBL
MSPLSSRLSRGVSKTPITASFEFFPPKTEKMGETLWNTVQRLAPLNPSFVSVTYGAGGST
RERTHKTVERILKETDLAPAAHLTCVGSPKSEVDAIVKDYWDLGVRHLVALRGDPLAGIG
ALYEPHPEGYAYATDLVAGIKKIANFDISVSGYPEKHPESGSWQKEIDNLKRKVDAGADR
IITQYFFDNDLFDDYLDRIAAAGINIPVIPGILPIHNFEQTMVFSAKCGTSIPEWVARRF
SGLHNDPDTRKLVGVAIACEQVMDLVDRGITDFHFYTMNRADLTFAICHMLGMGKPEHQQ
VAA
>A0A3S3QV10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endozoicomonadaceae bacterium GTF-13|TrEMBL
MNTQNRFLKRYSFEFFPTKTDAGAANLLATAQQLASYQPDFFSVTYGAGGSTRDRTVSTV
LGAQQSTGVPTAPHLSCVGDSKQEILDLLDHYRANDIQRIVALRGDLPSGMGLASSEVRY
ANELVSLIREHSGDHFEIEVAAYPEVHPQAPNAERDLLNFKRKVEAGADAAITQYFFNAD
SYFHFVDRCESVGIDIPIMPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDIVSI
QRFGEEVVTQMCERLLEGGAPGLHFYTLNQAAPSLKIWDNLKLSERR
>N0B6H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium denitrificans 1NES1|TrEMBL
MTQGNERKSKLLGSGDIVVSFEFFPPKTEKMEETLWSSIARLAPLRPEFVSVTYGAGGST
RERTHATVTRLLRETQLKPAAHLTCVDATKDEVDAVARAYWDAGVRHIVALRGDPAQGAG
TKYEPHPGGYTNAADLVAGLKKIANFEISVAGYPEKHPESPSVDADIENLKAKVDAGADR
IITQFGFDNARFLRYLERARAAGIWVPISPGIVPIHNFKQVSGFAKRAGASVPSWLARRF
EGLEEDSATTHLVAAAVATEQVMDLVDEGIKKFHFYTLNRADLVYAICHLLGLRPARSNA
DANAA
>A0A095C412|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus gattii serotype B (strain R265)|TrEMBL
MPHLTSLIATHNGPFHNYEFFPPLTDPGFVNLLDRIRRLTSPPFQAPLAVSVTWGAGGST
AERSLELAQQIVGMGVEVILHLTCTNMPKDKVDTALQRCKDLGISNILALRGDPPREEEY
AINPTSTPDFFKHADDLVRYIRQTHGDYFCIGVAGYPNPHPDSESEEEDFKWFKAKCDAG
ADFIVTQLFYDVDVFSEWVKTCRAKGINQPIIPGIMPIQNYASFRRLVNLTKCPVPDSIT
SDLQPISSDDAAVKRYGAELATKMVNQIIESGLVPGVHFCTLNLEKSVRTILDNLGWSAT
SKTSASDGVVKNKLIQDDSQAVNGIQINGKAGKTQNPAKDLSISPSEANQLAQLGLTSTT
LPPAPKTGLSAQGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKEWGVP
VSTSDLSALFTAYLHSDPNHLTTPFCDLPLSPESHMILPHLLALNSAKVQHWTVGSQPAV
DAAKSEDGVVGWGPRGGYVFQKAFVEFFVTEDEVNRLTKKVEEEGKGLITMYAANRKGAF
RTNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWTEWSLLYPRNTPSRKL
LEGIANEWWLVSLIHHDYKDQDALWRFLLEDLQ
>A0A2N5J270|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium anseris|TrEMBL
MPIFSLEIFPPKRTAPVGTIYDTLDGLQGLEPAFISVTYGTGKSVDRTATARIANTVRAE
YGIPAVAHLTAQYLDEAGAEEALDLFDQAKVAGVLALRGDRNPEREPANVFHHASDLAAF
IRERRPDLPIYGACYPEKHPQAASLDEDIDNLKRKVDAGVTHLISQLFYDDEDFLRFRDK
ARAAGIDVPIEAGIMPVVNAGSVRHMADLCASRIPERLAVMLEMWGQDPASLKEAGVVYA
SEQIRDLVARGVDGIHLYTMNRPCAARRIWANTKAFFA
>A0A6H3FBT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio legallii|TrEMBL
MNIGRKIRAAGAPFCSLEFFPPADAAQLPEFYATVERLRGLAPLFVSVTYGAGGARQQNT
LTVTTELARRGLTAMAHLTCVGAEAASIAAFVAALRAAGVDNVLALRGDPPARQAGDQPW
DWSRARFRHAADLVAFVREREPGMGIGVAAYPAPHPESPSFAEDRRRTAEKLRAGADFAL
SQLFFDAREYEDLVAHLRAQGIAIPIVPGILPIQSFDSLRRVLSLCGANIPGKLYLDLEA
ADARGGAQAVRDVGLDFAVRQIRRLLDSGAPGIHLYTLNKAELCLRLAQEAGLACGQPCA
TRS
>A0A7W2IXM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. xlx-221|TrEMBL
MKVTEHIEKANGKTLFSFEILPPLKGQNIQSIFDAIDPLIEFQPPFIDVTYHREEYTYKE
VANGLLEKKVVKKRPGTVGICAAIQNKYKVDAIPHILCGGFTKEDTENFLIDLDFLGIEN
VVALRGDAVKSEIYFKAEKNGHRYASDLVTQITELNKGVYLDDELLNTSQTNFCIGVAGY
PEKHMEAPNFDTDLNFLKQKIDNGADYIVTQMFFDNAKFFEFVEKCRKADINVPIIPGIK
PLTTKSQLNMIPHRFKVDLPDQLVLDAIKASDNNAVKQIGIEWCIQQSKELKAAGVPIIH
YYSMGKADTIKTIAQAVF
>A0A822LL92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. CAG:131|TrEMBL
MNILESLKDKLLVADGAFGTCYVGMYGEQGTVAPELANMRHPERVLEIHKEYVKAGAGLI
RTNTFAANTASLDADTDYVISNVRAAVKLAKQAADGEAGTDHKKVYIAGDIGPIPADAGL
TLNERVSQYKLLGEAMQDMGVDIIWFETFPEFNVLEPVVKHLKARKDTPVMVSFCVNQFG
YSNCGFSARALLSQVAGNQDVDCVGFNCGVGPYHMLQLLKKLDIDCGKPVSVMPNAGYPK
FTQSRLVFNDNKEGFIDKIQDIAALGADIIGGCCGTNPEYIHQIMERVKTGDIAKAAKVH
VEKVQADSAVKDNFLKGRLERGGAATKNADGHKHKLIAVELAPPVDVNDQKLLDAAHILK
QSHVDVVTFPDSPSGRTRADSILMAEKVHKETGLRVMPHLCCRDKNAIAIRGSVLGAQLN
GIKDFLVITGDPVPVMFRQTTRSVFNFDSVGMMKLLQSMNEEVFSGDKITYGGAINQNRL
NAKFEIDRIKRKMEAGAEFFLTQPVFSREQAQILRDMKAETGATILVGIMPLVSRRNALF
MKNEMAGIEIPDEIIERYSRNATRQEGEECGIQIARDILEYTSDFADGYYFSFPFNRVHM
LAHIVD
>A0A021WXX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shinella sp. DD12|TrEMBL
MAHIDENPLGPHLPLDPLPGHSSLGRLERVLRRGEFAVTTELNPPDSANPEDVYERAAIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAAMG
VTNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNSKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCYILVGV
GPMASAKTAKWIRSNVPGIHIPDSVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEIVHDSGVLKGRRPWKREPNPVDQLVAERIERTREGVEQNQQQMAEIAA
HHPH
>A0A1J5NKW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio hydrargyri|TrEMBL
MKIIDRIKDKSPFLSLEFFPPKEREQWPRFFGQVERLAELDPVFASVTYGAGGSFRDNTL
DIAAEMHRRFGLTVMSHLTCVGAEKRSIAEYVDRLRDAGIHDVLALRGDMPGNEEDIWKD
FRHASDLVEFVKADWPGMGVATACYPDAHPESPSIDDDLRWTCHKFNAGSDFSVTQLFFD
VRRYRDLVRRLESRGVTDPVLPGILPVLSMASLNRILSLCGANIPLKLYLELQEADQAGG
NEAVRRKGIEIARRQVRELLDLGAPGIHLYSLNNADVCLDILSGVPELGG
>A0A1C4VXC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora tulbaghiae|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTQAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWIAHPEGVRYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVDSDTAHFVR
KCRAGAEFAITQMFFDADEYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAQRFERVADDPEAVRRLGVEQASEMCEKLLDEGVPGIHFITLNRSTATREVWQRLR
AAARV
>A0A243P9S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. GW456-12-10-14-TSB1|TrEMBL
MSLPSIHPNWDLPPKGMTDGYSLEITAKDIDALREAAPAMAPETPVAVTFLPGESLEARI
EAARTVRALGFEPMPHFSARRLESGDDFEAYLAAVVREAGVTRCFIIAGDPPEAAGPYSD
SMSLIRTGAFERAGIKAIGVGGHPEGHPNMTPDQCFDILIAKCAEIEARGMAPLIVTQFS
FDAAPVLSWLEELRGRGIDAPVRVGIPGPAGIKTLMRFAARCGVGASASVLTKYGISITK
LIGTAGPDKLVDALGKGLGSQHGKVRLHFYPFGGLARTVEWINNYTKSR
>A0A0C1JEH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria sp. ANG-S4|TrEMBL
MSKPEISFEFFPPQTLEASFRLWDTVQTLAPLEPRFVSVTYGAGGATRELTRDAVSTLHK
SSGLKVAAHLTCVDATRAETLDIANGFAEAGVTDIVALRGDPPKGQDQFTPHPEGFANSV
ELISALAETRRFNIRVGAYPDVHPEAQCARTNVDWLKAKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGILPIENWKGARNFARRCGTRIPGWVEQAFEKALRDDREELLAT
ALCTELCSDLIEGGVDKLHFYTLNRPELTRDVCFALGITPRTALQNVA
>A0A2S7CMB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas codiaei|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRHFKAKVDAGADAAITQYFYNADAYFHFRDA
VERLGVAVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGRKMQAYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1G4XCM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira sp. Nsp1|TrEMBL
MESQKKFSPTFSFEFFPPQTPEGIEKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETV
LEIQAEGYVAAPHLSCIGATSENIRSMLQKYRDGGIRHVVALRGDLPSGMAQGGEFRYAN
ELVTFIREEFDDAFHIDVASYPEYHPQSNSAQEDLQNFKRKVEAGADSVITQYFYNADAY
FSFIDACEAMDIRIPIVPGIMPINKFSQLARFSDACGAEIPRWIRKKLEGYGDDSASIRA
FGLDIVTDLCDRLLNAGAPGLHFYTLNSAGPTTTIWQRLGL
>A0A386WD38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora tulbaghiae|TrEMBL
MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTQAGEKLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGDPGGEWIAHPEGVRYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVDSDTAHFVR
KCRAGAEFAITQMFFDPDEYLRLRDRVAAAGCDTPILAGVMPVTQIGTIERSVQLSGAPF
PPALAERFERVADDPEAVRRLGVEQASEMCEKLLDEGVPGIHFITLNRSTATREVWQRLR
AAARV
>A0A1V5GYZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium ADurb.BinA184|TrEMBL
MDRVLANGSSDRGATVQPHHPQRVFHIEILSPRQNAPDLDAGLAALADKYRQIVDAGHVA
CFTDNPLGNLAFQGTELIQELGLPVRPGQVSIHLNTFHTRRDLDAILDAATNLKIDDILV
ISGDGSERLPKLRGRDLGIEAETVTSVELVAHLQRTCPGRFRIGVAFNPYEPREHEMEKL
RRKLDAGAGAVTTQPIIGQDPSIADLRALGATVIVEAWMSKKLHLLSDCVGYALPADETY
DPLENLRTLLRTYDGCGFYLAMLGMKTQFPLLRDIWS
>A0A7U4H5M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum|TrEMBL
MHSPMFTLEVFPPKRNAPVDTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPGLKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRAAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNAEPLFLGTQG
>A0A857DGE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalobacter restrictus|TrEMBL
MIRDITSELVPGRGSKEVSQEKALQLAEQAAKGKKIHAVSLTDNPGGSVGINPEGIGREI
KSLGIDAIIHVACKDKNRTQLESQLFSLERSGLHNLLVLTGDHDPGNFFGRPKPVFDLDS
TQLLAFIAKMNDGLELPTAKGVNKLQPTHLFAGAAVSPFKATEAEQMLQYTKLRKKIENG
AQFIIPQVGYDVRKYHELYQFVKHNNLRGCLMGNIYLLTYGAAKAMSMNKVPGCVITDKL
VAELEQEKQSSDKGAAAMLDRAAKLFAILKGMGYKGVHLGGHNTTYEQVEYIIDRGNELA
ANWQDYVREFDYPQKNGFYVYAKDEKTGLNTAQKSNDYNNYEKSFDLNYKMSRVVHKMMF
EPNKGMFGFMRGFCHAIKDSALEKPFHGIEHFAKSCMYNCQDCGDCALIDVAYVCPMGNC
PKNQRNGPCEGSYNGWCEVYPDKQKCIWVKAYYRLKGYSEEEKLNSYHVSPYNWEKQHTS
GWINFFEGQDHSAERLGIKPRTNFEEKE
>A0A1S8TM29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. BL-8|TrEMBL
MIKDYLQDNILIFDGAMGTYYSELTGNDISYCEFANLDDRDTIKKIHKEYINAGAKLIRT
NTFSANTHDLGVSYETLKNIIKSGIDIAKEVTQNTSVFIGASIGPIKEDNIDESQEDILK
EYKYIVDCFLNNNINIFVFETFSNYKYLKEISEYIKGKDSKSFILTQFAVKPDGFTRDGI
SASKLIKKVKEIKIIDSYGFNCGSGPTHVAEFIRTIDIENDIVSAIPNAGYPEIIHERTV
YPNNPVYFANKVNAMTTLGVSIIGGCCGTNPNYIKELVALIKNNSNEINSYSKKEEIKEY
KEKTENTFKDKLDKNEFAIAIELSAPINTDISKLMAGAKICKENNIDLVTIPDSPMSKVR
ADSTIIASKIKREIGIEVMPHICCRDRNTNAIRSSLIGSHIENIRNILAITGDPISDANK
IETKSVFNLNSFRLMKLINDMNEDLFKEDNIYIGGALNLNVLNKDVEFNRMLKKIDNGAK
FFLTQPIYEDNAIEFLSKIKAKTNVKILAGLLPIVSYRNAVFLNNELPGVKIPERYMKMF
SEDMSKEEAQEIGINIAVEIGNKLKGVSDGLYFITPFNRVNMLIDIVKQLQLS
>A0A7X9V4E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. pelargonii|TrEMBL
MYPDTPSLASTITDAYSLEVGATDMPALAAAAPRILRGSTIAIPYLPSQNDDARLAAAQT
VRTLGFAPMPHLSARRIASLDALHAFVGRAVDEAGVERCLVIAGDAPSAIGPFSDSVSLI
DTGVFERSGITTIGVAGHPEGHPGMPATDQWDVLERKCRSIAERGMAPLIVTQFAFDADI
VLTWLEALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACASMLSKYGISIGKLFGSA
GPDRFVDRLATGLTDAHGDVSLHFFPFGGIAQSVAWVEQYRSRSAAHILSTSASRRSQ
>A0A6L5EJG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. zg331|TrEMBL
MSTAHLYIGYRPGVRTDTPTVSFELYPPRNPSRGSGVWAGIGRLIDTAPDYVSVTYGAAG
KSTDTRDRSVQVLLNVLDRHRDLPAVAHLTCLGSTREELTLLVRLLLRAGIRDFLALRGD
PPGGDPHYQPPRGGPTRAVDLVRLIREIAAEELPLGVGRGYNGAGAATAARPEDYVSIAV
AAYPATGGQARANDIAALVEKERAGADYAITQVFYSPEDYASMVRELSMVGSRLPIVPGI
MPLHDLNRLRTMEKLAGIAVPERIERIFSQATSPERLVRDTLGATVDLIGGVLEAGAPGI
HLYTFNRPRPTLDILEYLRASGYLGRTTGARTPGDPHVDTELVSLALRRMTPNYY
>A0A6P7S4G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Octopus vulgaris|TrEMBL
MGEINNKQECNGLRKSSMKNNFISLTDQMKLRMSSNDPWFSLEFFPPKTTNGARDLFDIM
ECFAESQPLFCDMTWHLKNDPQNLEKPTSSLCMASTMLNYFNLPTMLHITSGSQSVSEIK
NILNKAKDQGIRNILALRGDKFPGHVASTVDELPYAVDLVRLIRKEHGDHFVIVVAGYPS
GHPECASYEEDLKHLKEKVDAGADFIITQLFFEMDTFEKYVKDCREIGITCPILPGILPI
QSYLSLRHVSKLTQLSVPEEILNSITPIKDNDEAVRNFGVHHAVELGKKLLNSGLTKGMH
FYTLNQRFATTAILKQLGLLNEEISKPLPWKPSVNYVRLEEEVRPIFWKGRRKSYICRTA
DWNKFPNGRWGNSSHASFGNLTDYYMFYLNYSSNEEQLKSLGFQLETEQDVWNVFYCFIK
GHENQNGVKVTHIPWSDDALSPETSLIADQLAYLNKNGVLTINSQPAINGFSSTHPIFGW
GNPDGYVYQKAYLEFFTSKENVEVLKKLLVNYPQVNYHIGNSQGDMDYTNCDETQPIAVT
WGVFPGMEIIQPTVVDPIAFKIWKEEAFSLWKTNWRDLYDPNSKSHKLIDYFYENYQLVN
LVDNNFVQTTCLWEITTKMLSGETN
>A0A373DWB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter sp. wl10|TrEMBL
MSAVLLTGSTPTRARFSFEVFPARSGAAALALGHAVQHLSAAGPDFISVTYGANGSNRDA
SLDLLRYLRDHTDALPLAHLTTVGESREALRETIHRVMDAGVHDFLALRGDPPRGLSEDD
PRVAGSLSSLELAELIAEARAERPPLTSVGRTAVAAYPNGHPLSRSRAEDIEWLIAKQEA
GAQLAITQLFFRAEEYLSFASDARTAGLAIPILPGLMPVSTSAQLRKVAALAGRPAPEGL
EEEIEELGGYAPELGVEHTVALARELLAGGAPSIHLYTFNRHEQVLAVLRELALLTPDPV
R
>A0A0A2KHX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium italicum|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKALGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRQTHGDYFCVGVAAYPEGHPADTFQDVQDPVRDIPH
LVEKTQAGADFIMTQLTYDIEAYQKFENTLRNHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPISRRMEELKHDDDAVKRAGVDIVSEIVGGMRDIPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPESSDAGDLAIEDGPASIPLDFPGRALRRRRASSINSQPHNRVIVDKL
SVHESSQDSVHEARADSAGVPAPPPNRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTANSARRLWGHPVDSKDMSTIFRRHVSGELHMVPWSEGGAEEDGEG
LNAETELIRPELLKLIDGRGWWTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFC
SSNDYINILKPMFAKHGHDKLTWFATNIKGDFESSLPIQPADVELDDLGSNPESVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPSETYLDTTKNDSWLVCVV
GQQFGAGTKQGSKEEEDEVKWMWRVLAGEEA
>A0A2G9WTU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pleomorphomonas carboxyditropha|TrEMBL
MRFSHNIGALDLGVSFEFFPPKTEKMEETLWASITRLAPLGPRFVSVTYGAGGSTRERTH
ATVARIVRETDLKPAAHLTCVGASRAEIDDVVRGYHDAGVRHIVALRGDPVGGLGARYQP
HPDGYASTTDLIAGIRAIGDFEISVSAYPEKHPESPDVAADIAMLKRKVEAGATRAISQF
FFDNDKFERYVDRVRAAGIDVPIVPGIVPVVNFEQSAAFAQKAGASVPGWLAQRFEGLEN
DPATRQLVAAAVCAEQVMDLIDRGFRNFHFYTMNRADLVYAICHMMGLRAKTEPAADAIA
VSA
>A0A416BU53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF37-7|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPELCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A3P6TXN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Onchocerca ochengi|TrEMBL
NIHSETSSTSVAAGCLDYCGMDTVLHITCCPYTKEQSIRHLEQSKALGLKNILALRGDLP
RQDENPVLYKYRALDLIRWIKEEYKDYFTIACSGYPAGHPEAPSYRADLLYLKAKVDAGA
DFIISQIIFDGQVFEKFLRDCREIGITVPIIPGILPIQSYESIRRIAELSQLIIPDSILA
SLEPIKNDDDAVRNFGIRYAVDLCQTLFTNGSATSIHLFTLNREASSREILQQLGLWSRS
PVRALPWRSFGENHPVRCKEDVRPIFWSLRPKSYVFRTREWDEFPNGRWGNSSSPAFNDL
KDYYLFYLKGQPTKVEQLRMYGERLETLADVQKVFINFIAQNINENGVKVNQLPWNEQYD
GIRAETSLIKDQLLWCNSNGFLTINSQPSVNGAPSTDPFVGWGKPGGYCYQKAYLEFFTS
QANAEVLWNLLPSYSRLNCHIVNHDATIDWTNTETTMPIAVTWGVFPGSEIAQPTVVDPL
SFRVWKDEAFDAWLNWSSIYAEGTSSRCLLEKIYNEYCLVTLVDNDYPKSTIIFDCLAQL
VSKNFGEIL
>A0A1M6E0Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquimarina spongiae|TrEMBL
MKVTDHIKRAKDKTLFSFELIPPQKGRSIQELYDNIDPLMEFNPPFIDVTTSREEFIYID
RDGLLDKKLTRMRPGTVGICASITHKYNVDTIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFTPTKGGHCYANELVEQIVNMNKGQFLHEVIETDNQSDFCVGVAGYP
EKHLEAPSMDSDIRRLKDKVDAGADYVVTQMFFDNKKYFEFVEKAKEAGINVPIIPGIKP
VAVKRHLQLLPQVFKLDIPDELVKEVEKCKTNKEVREVGIEFAIQQSKELMEYGVPVLHY
YSMGKSDNIKKIASAIF
>D5ZPS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces viridosporus (strain ATCC 14672 / DSM 40746 / JCM 4963 / KCTC 9882 / NRRL B-12104 / FH 1290)|TrEMBL
MRGLRRGGGRLPGASPQIGRPGRRHPPLRRQVPQRCRLRHHPDVLLVFRADDYFRLRDRL
ASAGCHVPVTPAIMLAPHSDRIRRFARFGNATVPDDLARRPEAARNDPGQANRAGVAHAT
ALARRLLDAEAPGLHYLTLNRPTAALEIHRSLPLPARADGSSGTKASRGTARPSGTPA
>A0A2M8WP34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yoonia maricola|TrEMBL
MTIPSVSFEFFPPKSLEASFRLWDCVNTLAPLDPTFVSVTYGAGGTTRQLTHEAVTTIHK
TSGLNVAAHLTCVDATKAETLQIAKGYADARVKEIVALRGDAPKGTDRFVPHPQGFDSSV
ALIEALADLNAFNIRVGAYPETHPEAADQAADIAYLKRKFDAGATSAITQFFFEADTFFR
FRDACVKAGINAPIIPGILPIENWTGAQRFARQCGTHIPQVVQDAFENATRDGTTDLLAT
AIATELCDDLLQGGVEHLHFYTLNRPELTRDICHALGVTPKVRLQNVA
>A0A259UWD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa acidovorans DSM 3132|TrEMBL
MSEAVDKKAILKTDSKLEKLYSLGHFVVTGELGPPQHANGHDLEYHAGELKDIVDGFNLT
DNQTAIVRLSSIAAGIHVMKGGGTPIIQMTCRDRNRIAMQSDLLGAYSLGIRDVLCLSGD
HQSFGNHPTSKNVYDVDSVQLISMVKKMRDEKKFLSDVAIKSDEPRFFIGAVENPFGDPF
EFRAIRLEKKVNAGADFIQTQAIFDVEKFARFMEMVVDRGIHERTKITAGILPVRSVKAL
QYMKKDVAGMEIPDSLIERMKKTEDPKKEGIQVAIELCNQLKTIPGVAGIHIMPVGWEAA
LPEIVKGAGFLPRPKVE
>A0A1F8KHZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium GWB2_49_20|TrEMBL
MERRLKAGQFVVTSEVAPPVTIATKKLISNIELVKPYVAAINFTDCPSATPRMSSWSCSA
TAIKQNAEPVMQIAARDRTRVGLQAEVMGAYNLGVRNILCLSGDSMSMSPSPRGRMDIVD
LDSIQMLWILRRIRDEGKYLDGREIKTPPKYFLGAAASPFASDPRFQAIREHKKVNAGAQ
FFQTNLVFDADGMEIWLNELAKRNILDKVYILVGITPLKNLRMATYMNDEVPGVFIPDPL
LKRMEKAGDGAAEEGLTIALELVEKIRKIQGINGLHIMAVGWEEIVPRLVTEAGLLPEGF
VQPAA
>A0A2N1XQM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium HGW-Gammaproteobacteria-3|TrEMBL
MTTNDALIYAADGSDRIFDKTILQSLLSSFSIEITVKEAAKIGDFSDHLPIGTEVYIVAT
PSTKPNDVVDLAKRIRDEGMIPIPHIAARAIPSVEILDRWLRRLSVEANVTAALIIAGGN
YDRPVGTLTSSMALVKSGVMEGNGIEDLRFAGHPEGHPVISHHELMEVLLEKQTYGEQKQ
LTTSLVTQFFFDFTAMAEWERQLLRCGVHMPVRVGFHGVASLASLIRQARYCGVGASIEV
LAKQPAKMLNLTSSPKPL
>C4ZCX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agathobacter rectalis (strain ATCC 33656 / DSM 3377 / JCM 17463 / KCTC 5835 / VPI 0990)|TrEMBL
MKITQIHTNKPQSLSFEIFPPKKEEDFKNIDEMLEILCDCHPEYISVTFGAGGSSNNNKT
IEIAKKIKNQYNVEPVVHLTCLCYNKAEIDEFTRQLSYEGIENILALRGDRNPNVPAKED
FLHASDLIKYIKDTTGDQFCIAGACYPDIHPEAADKVDDIKNLKKKVDAGAELLLSQLFF
DNDTFFNFAEDCRLAGINVPVIPGIMPCINAAQIQRMVTMCGAKFPEKFQKIVHRYGDNK
AALFDAGMSYCESQIIELLANDVEGIHLYTMNNVRVAKRLTEGIKNLI
>A0A8C9E3J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocoena sinus|TrEMBL
MVNEPRGHGGPSPRWEGSSSGSESSKDSSRCSTPVLDPERHERLREKMKRRVESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKRLGLKNILALRGDPTGDQWEEEDGGFNYAVDLVKH
IRSEFGDYFDVCVAGYPKGHPDAESFEAGLKHLKEKVAAGADFVITQLFFEADTFFRFVR
ACSEIGITCPILPGIFPIQGYRSLRQLVKLSKLEVPQQIKDVNRALSLCRELLASGSVPG
LHFYTLNREVGPPQRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRW
GNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFAHYLSGGAEPERDP
AWLTLPSLMKGGAAAAWNRRGILTINSQPNINGKPSSDPVVGWGPGGGYVFQKAYLEFFT
SRETVEALLQVLKKYELRVNYHIVDVKGDNITNAPELQPNAVTWGIFPGREIIQPTVVDP
VSFMFWKDEAFALWIEQWGKLYEEESPSRTIIQHIHDSYFLVNLVDNEFPLDSCLWQVVE
DTFELLSGPPQGKRETEAP
>A0A7G7BRD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces finlayi|TrEMBL
MALGTPSTRTDHARTVRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVKATQQIAEDSTLTPVAHLTAVDHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVRHPRGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDIGHFVD
KCRAGADYAITQMFFDPEDYLRMRDRVVAAGCDTPIIPEVMPLTSARQLERFAQLSNASF
PSSLKERILAAKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>P73677|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechocystis sp. (strain PCC 6803 / Kazusa)|TrEMBL
METGPQVWAMTKPANRKNSVKISCQRGSHRSQLKPPLSPLDVMTISRFRQAAEAKEFLIT
AEVTPPKGGNPERMLAVAAKLRGRVHGVNVTDGSRAVLRMSSIAACVLLQQRGIEAICQM
TCRDRNLIGLQADLMGAYALGLRNVLALTGDPLKAGDHAKARPVYDLESVRLLSLIRSLN
QGLDFNQAPLVDGRLDLFPGAAVDPQLKSWSGLQSRFERKLTAGAQFFQSQLITDFDRLD
KFMTQVAVGCGKPILAGIFLFKSAKNATFIKRVVPGVNIPDALIDRLARAEDPLKEGVAI
AAEQVKLAKELCQGVHLMAIKKEELIPEILDQAGIAPLEN
>A0A841CX13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planomonospora venezuelensis|TrEMBL
MALGRPSILPDRVPTVRELLAGGGRSFSFEFFPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGGTRDRTVEIVERIAHETTLTPVAHFTAVNHSIRELRHLVGRFAGAGVRNILAVR
GDPPGDPTGEWVRHPEGVLYAEELVRLIRQSGDFCVGVAAFPYKHPRSASVESDTEYFVR
KCRAGADYAITQMFFRAEDYLRLRDRVAARGCDTPIIPGIMPVTQMSTIARSEQLSGAPF
PPEVAARFEAVAGDPAAVRRLGIEHAAELCQTLLDEGAPGIHFITFNRSSATREVFQALD
FAREAAPLTA
>A0A1U7JKZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudovibrio exalbescens|TrEMBL
MAYIDPGRRFRLTGHSDIAVSFEFFPPKTEKMEQTLWNSIERLAPLEPNFVSVTYGAGGS
TRERTHATVSRIVKETNLKPAAHLTCVDATCAEVDEVVQGYWDAGVRHIVALRGDPAAGV
GEKYIPHPGGYQSTADLIASIKRIGDFEVSVSAYPEKHPESPSWDVEMDVLKAKVDAGAT
RAITQFFFRNEDYLRYVERVRAAGIEIPIVPGIVPVTSFKGISSFAAKTGASVPDWLARR
FEGLDDDPKMRELVAAAVAAEQVMDLVDHGVSDFHFYTMNKADLVYAICHMLGLRESEAA
PEPVATA
>A0A1H0FD58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afipia sp. GAS231|TrEMBL
MTEVTSPVSDGPRELHSPKISFEFFPPKTEDMERSLWETINRLAPLAPNFVSVTYGAGGS
TRERTHSTIARILKETRLTPAAHLTCVGAPKGEIDDVVARYHDVGVRHIVALRGDPTTGI
GTAYQAHRDGYQSSPDLIEGIKKHYPDIEISVSAYPEKHPESPSLDADIDTLKAKVDAGA
TRAITQVFFDNDLYFRYLDRVRARGIDIPVVPGIMPMHNFKQARGFVTRAGTTVPSWLAD
KFEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPHGA
QKAA
>A0A090MGG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afipia felis|TrEMBL
MSDTPPSAHTQAARPSISFEFFPPKTEEMEQNLWGVINRLAPLSPNFVSVTYGAGGSTRE
RTHSTIKRILEETSLTPAAHLTCVDATCADIDDVVDRYHEVGVRHIVALRGDPSGGIGTA
YRAHPNGYQNSADLVASIKRRHPDMEVTVSAYPEKHPESATIDADIDVLKAKVDAGADRA
ITQFFFDNDLYFRYLDRVRAAGITIPIVPGILPVQNFKLAKNFATRAGATVPDWLAEKFE
GLDDDAETRKLVAATVAAGQVQKLAKHGVENFHFYTMNRADLVFAISHLLGIRPNGSQQA
A
>A0A4P9ECM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. SC05B48|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMLGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVQLLESGVDLGGNPLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPALLEQAEI
>A0A1R4F2E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gulosibacter sp. 10|TrEMBL
MPFPFSFELFPPRTAKVAERMPEITRVLGEAGPEFISVTFGAGGSSRDASLDVLRQIRRN
GDARPLAHLTCVGSSEAEAGAIIDRFIENGILDFLALRGDPPKGLAETDEFLGDLRSGAE
LTEFIRRRRDARRTPGEEPLLVVAAYPNGHPQSRSIEQDYDALLAKQAAGANLAITQLFF
EAEDYLRFVEGARARGVAMPIMPGVMPITSVARLQRMAELAGEAVPERWRRSLDACRSDR
ARRELGIAHAAAMSHDLLEGGAPGIHVYTHNRTDEPLELLSRLGAISPADASVEPVAA
>N8PLX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NIPH 236|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A2X3L5W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. Ea1.12|TrEMBL
MSTPTVAECLASGRTSFSFEFFPPRTAEGERHLWTALREIEALHPTFVSVTYGAGGSTRD
GTIRVTERIATETTLTPIGHLTAVNHSVGELRQVIGGYAGAGVRNVLALRGDPPGDPQAE
WVRHPDGLGHADELVRLVRSLGDFCVGVAAFPDKHPRSPDLETDARFLVRKLDAGADFAI
TQFFFGADDYFRLVERVRRLGCDAPIIPGVMPVTNLAQIERMAQLSGADFPADLAARLHE
VADDPAAVRAIGVEVATELSERLLAGGAPGLHFITLNRSSATREIYQSLGR
>G3B7S7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida tenuis (strain ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC 10315 / NRRL Y-1498 / VKM Y-70)|TrEMBL
MFITDKVANIDQGKFVSFEFFPPKTDAGFRNLLARLSRMKALNPLFITITWGAGGSTSEK
SLELAAICQKQLGITTVLHLTCTNTNKEIIDAALVQAKKNGIRNILALRGDVPRTEEYWT
PNCDFLSATDLVKYIRSQHGKEFCVGVAGYPEGHVDGSDYTNQNPEKDIPYLIEKVQAGA
DYIITQLFYDVDKFVKYHQLLKSYDELKDLLVIPGLLPINTFNSFKKATKLSHATIPQSI
LDRVSRHKLNDDEVKAVGIKILNEIIAEVSEKTDIKGFHFYTLNLEKAAASIIETSSVLQ
DGLKVRDDIAESDEEIEIEIPQKSFKRRQSSVSSGVDPKPHFKSLIAISKGKGQMGKDAN
WDDFPNGRFGDSNSPAYGEIDGYGPNLKVESSEKAVELWTTPESTLDLARVFIDYLSNKI
PQLPWVDTPLDIETSIIQEQLFELNLRGWFSTASQPATNACPSNDKIFGWGPANGIVYQK
AFVELFVPKHDWDQKIFPALKPQIENKTITYFLGDNKGQIQTNLSNHQSKSAVTWGVFPS
KEILQPTLIDLDSFKAWNEEAFLLWLEWARCYKKATNTYTFLNFIYENYYLVSLIHHDFV
DENGLWDSLLDIE
>A0A5Q0GHD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anabaena sp. YBS01|TrEMBL
MDDNHSYTALNYFSKAAQAGEFLVTAEVAPPKGGNPTHMMEMAATLKGRVHAVNITDGSR
AVLRMSSLVASAILLQQGIEPVCQMACRDRNRIALQADLMGAHALGIRNILALTGDPVKA
GDHPEAKAVFDLEAVRLLQLIRKMNQGVDCNDKPLTDGATDLFVGAAVDPQCASWSGLQS
RFERKIEAGAQFFQSQLITDFERLEKFMDKIASVHKKPVLAGIFLLKSAKNAQFINRCVP
GVNIPEHIIERLAKAKDPLEEGVKIAAEQVQIARQLCHGVHMMAVKREDLIPQILDLAGV
SPVNRMLVK
>B2IMQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae (strain CGSP14)|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQYMQELTPYFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A120DG29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio toranzoniae|TrEMBL
MGYTYAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVVTL
>A0A852ICU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tricholaema leucomelas|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTASAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVNGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAGSYEEDLKYLKEKVFAGADFIITQLFFRSETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6J4U1B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Thermoleophilia bacterium|TrEMBL
MSILEERLTAGTFVVTAELPAVDGGGLDAVRRHVDPLRPWVDAVNATDNTAAHAHASNVA
VAIALLRLEVEPILQVVCRDKNRLALQADIMGGALHGVENVCCLTGDDVTAGDEPETRRV
FDLDSPQLVQVATGLGQGRYVSGRTIEAPPHLFVGAVENPFTHPLPGRVDRAWKKARAGA
RFLQLQIGYHPERLGAFMVEATRSGLAARTAILPTICLLPGARGLRFMDERVPGISVPAG
TIERVETSSDPREAAYDLALQQARHALDLPGVAGLHLVTFRRDDAVARLLTDLSIPPHAE
RLPPNAHSPALVHP
>A0A7C5BSI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MSGQRKLPSVFQERVVVFDGAMGSLLHERGVNASRPFEELNLTSPHLICQIHAEYIQAGA
DAIETNTFAANRFRLARYGLEERVYEINSAGARLARNVAGANAIVAGSIGPLGVRLAPIG
PLSAEEVTAAVAEQVRGLVDGGVDLIILETQDDLDVACAMLQAVFDNCELPVICQFTVGD
DLATATGDTLDDVVIRLSSCPVSAVGVNCGVGPEGALRAVQALSEITELPVSAQPNSGFP
ANVDGRTLYISGAGYFADRGVEIVQAGASIIGGCCGTTPAHIQALAAKVKAMPRPAGAVV
RAPRKREIPCAAVCEHSPLLSKMNGEFVTVEVTPPKDTNYKDLVNKLRPLVEAGVSAVDV
TDNPMASMHMSAIAFAHLVKEELGIATILHLTCRDLNLLGMHSALLGAAALGIDGILALT
GDPASVGDYPGATSVFDVTSDGLARIINSLNCGVDYVGKEIGQPTNFAIGAAFNPFADDM
EKEIARLSKKREAGADFLMTQPVFDMAALKAAVSMLPSDWNAPILVGVLPLRSARHAEFL
HNEVPGITIPDALRAKLASVDADAAKQIGIEYARDIYIAARQSFGGVYFMPPFNNYDAVR
EVMVGT
>A0A7Y5BDZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MKLSDALAQPVVCGDGAYGTLLAARGFPKQPYDLANLEAPELVADLHRLYFEAGAVLIET
NTFTANRFRFVDLRDDLYEINRAGARIAKAACGDGAVILGAIGPAGKPMYPLGSISSSEV
IESAREQARALEEGGVDAFLLESFLDLDELERVVEGVRQASNLPIIASKAFIEDGEAISG
GLPYQCAKRMAAMDVAAVGANCVVGPQRMLDLVRMMTEATSKPVLAYPTPGMPTLIKGRV
AYDTDPTYFAKACRRLAEEGAALIGGCCGTTPDHIRALSQELGRSPVQRAKRASVATRDY
ETKPLESTPRTEFGERIARGESTYSVELDVPRGLKLDRLMADVEAVRAAGAHTINISDGA
RARLRMNPTAVCHLIQSTTGAETTMHFSCRDRNLLAIQADLLGCHALGVRNVLAITGDPA
NIGDYPSATSVFDVDAVGLVRILGRLNEGIDLAGYGIGRKCGFTICVAFNPGSPRPEVEL
VRLQQKADVGAHAVYTQPVFDESLVEIALESCKKVGLPCLIGVMPLRNARHAEFMHNEVP
GILVPERLRAALADAPDDEAALDLGIGQALRLARLAKSGGAGVYLMPPANRITAAVKVLE
GIR
>A0A7L2B7J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heliornis fulica|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAADL
VKHIRNEFEDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLR
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGLVHGLHFYTLNREVATTEVLKRLGMWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSDIVTALLKVLKKYELRVNY
HIVNVKGQNITNSPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLDNCLWKVVDDTFELLN
>A0A3N0ZKR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes/Chlorobi group bacterium MS-B_bin-24|TrEMBL
MESILEKIKKKVVLFDGGMGTELYKRGIFINRCFEETNITQPELVKQIHRDYVNAGAEVI
ETNTFGANRFKLRRFNLQDKLYEIVRKGAELAREVAGEKVLVAGSVGPLGVQIEPLGPIA
REEAQEYFEEVIKPLLDSGVDLLIFETFINIDELRQAVKAAKRLTEKPIIAQITIDEDGN
TLTGTDPETTIKELESLGADIIGVNCTVGPQMMLNWLETVRSLTSLPISIMPNAGKPKNV
DGRNIYLASPEYFAEYTKLLIQAGVNVVGGCCGTGPEHIKRMASSISALSPKIKLEKVEK
IEVKAEHRVKPIERRDKSRLARRLTDGKFVKFVELVSPRGVDASKELQKARELFYNGIDV
INIPDGPRASARMSALALAVKIQREVGIETVLHFVCRDRNVIGIQSDLLGAYALGIKNIL
AITGDPPKLGTYPDATGVFDVDSIGLVNILNRLNNGLDIAGYPIGEPTGFFIGVGANPVA
FNLEEEFRRLYWKVDAGAEFIVTQPIFDVEKFKDFLKRIEHYRLPVIAGIWPLTSLRNAE
FMNNEVPGVSIPEQIIERMRKVADSKERSLEEGIAIAREILQEIRDRINGVQISAPFGRI
DMVFQTLEGMD
>A0A7C5BUD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MPAAGAEGGNTVTNSFADTLKSGGFVVTAQCTPPRGASAEALNACAGVLNGACAISVAEC
EDGVRMSALAACSHLIAAGAEPILHLLTRDMNRIALQASLLGAASMGVKSVLCTSGRHQT
LTDARSARGVFDVDPIQLIGIADAMRKSGVLEDGSRIEGGFDILLGTDTNPFSDPVELQV
IALDKAVASGADFVVTQPAFKLDKFNAWMELVRARGIHERTCIIASVMPLASAEQAAGLA
AKYSHLDIPDEALQRLQAAEDVRAEGVAMAVDMVRALKSIAGVRGICVMGDDCGAAKDVI
SSSGIAGS
>A0A8D9YIC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae SK-92-679|TrEMBL
MQINYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTY
GANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASYDELRQIAKDYWDSGIRRIVALRGD
EPAGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHV
ITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYE
GLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A832SQL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrobaculum aerophilum|TrEMBL
MEIVAELTPILYREKLLARLDALTRYVEKVDIPEAPGGKPSAHSIAVGALAKQLGIEPIV
HIRLLDINMTAYKSLLGGAYLLDIKYVVVLQGDPPAEGRPVGEISTEEAVAVAKKMGFKA
GALLSLRRDYKQRLKIGADFYLALHLREAEQLADLPPVIYPYILVKTEKNFDLFERLGQT
AVSPREALELVRKLEGLAPGVVLSVPRDFQTLLGLLQEVKIRP
>A0A7S1C6C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bicosoecida sp. CB-2014|TrEMBL
MPKLIEKIRAHQAAAGEETKDGEPTGKPFIAFEYYPPRTDDGVANLYKRLGRMAQQEPLY
VDFTWGAGGSTADLTLELTVESKKRFGLEPNMHLTCTNMPVEKITTALEGAKAAGITNIV
ALRGDPPAGEAKWEAVEGGFACALDLVKYIKEKHGDFFGISVAGYPEGHPSVINKVEEGR
ALSDAEKGRVVTMEDGEYVCSDADFAAEIAYLKEKVDAGAELIITQMFFDVDVFVSFVAA
CRAAGIAVPILPGIMVIQAYGGFKRMTAFCKSRVPKEVHARLDAVKDDSEAVKRVGVEIG
TEMSRALLAAGVPGLHFYCLNLEKVVVGIMENLGLAKPVDDAEGADE
>A0A3D1D509|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIERANGKPLFSVEILPPLKGQDVNATFKTLDPLVELNPAFIDVTYHRQEYIYKQ
KENGLLKRYQVRKRPGTVAICAAIQNHYKIDAIPHLICGGFTKEDTEDALIDLNFLGIDN
LLVLRGDPIKSEKSFVPEVGGHAHASELIEQITALNTGNYLDDELQESHAMDFCIGVAGY
PEKHFESPNLAMDLYYLKKKVELGADYIVTQMFFDNQKYFDFVKKCREMDINIPIIPGIK
PMTTFNQLTSIPQNFYLDLPEALAMEVLKSKDKERIKEIGIEWCIQQCKELIDFGVPGLH
FYTMSNSINTKRIAEAVY
>A0A0C9YLF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Laccaria amethystina LaAM-08-1|TrEMBL
MKITQKIQQSADNDKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGMETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPSGKDE
WEAVEGGFIHGIDLVKHIRRDYGDYFDIAVAGFPQHMALPPDERDQEIQWLKEKVDAGVA
FIFTQMFYDVQMFIDWVKAIRAAGITIPVVPGIAPIQTWNGFQRATSLAKIVVPQFFLDA
LEPIKNDDEKVREVGTRLVADMCRRILKEDIGIRGLHFYTMNLEKGTKMLLEELNLVPRI
ETIKPLPWRQSLTPNRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDALKLWGHPTSFADIASLFARFCTKKLSALPWSDQAPSRETSVIAEQLA
TMNEFGFLTINSQPAVNGARSDDPVFGWGPSNGYVYQKAYLEFFVNPTLLNLLLTHIERD
SNITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELGQQ
WAKLYEANSPSQNLITELMDTCFLVNVVHNNFHEPDAIFKPFLKAGAEYVAAKAKATAVN
GH
>A0A3B9P0W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellaceae bacterium|TrEMBL
MGNTTPISFEFYPPQTPEGVEKLAAVRQRLATVKPEFFSVTFGAGGSTQDRTLDTIRQIH
AEGHSAAPHLSCVGSTRDNVRAMLFAYKDMGIKRIVALRGDLPSGMASIGEFQYANELVS
YIRAQTGEHFHIEVAAYPEFHPQANSAREDMLNFKRKMNAGANSAITQYFYNADAYFRFV
EETRKLGVTAPIVPGIMPIVRFSQLARFSDTCGAEIPRWLRKTMEGYGDDNESVQNFGLD
VVTQLCEKLIAGGVPALHFYTLNQANASLEILKRLGYR
>A0A2K1P571|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrotoga olearia DSM 13574|TrEMBL
MKIIDLIKQSIKPILSFEIIPPNVGESIDPIFNVVDNLIDFSPKFINVTKHANEIEYVEE
NGEIIKIIKKKRPGTVGVSASIKHRYDIEVVPHLICTGFNKYQIEDILIDLNYLRIENIF
VVRGDKKRYTWKETDEYEHATQLVEQVTNMNKGIYTCPTKEHNPTNFCVGVAGYPEKHFE
SPNLEKDLDYLKLKVDMGAEFIITQMFFDIEYYKNFVNKVRELGIEVPIIPGIKPLGSKK
SLYNIPKNFHVNIPKAIVEEFEDAKSSQDEYIIGVKYGIKLIEQLLELGVPGIHIFTMGK
GKIVKDILNAFNGIF
>U1Q147|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces graevenitzii F0530|TrEMBL
MPFSNDIYACPCTHDHEPTLLSFEVMPPRKPSLEAPFWQTVDQLLQVRPDFMSVTYGAGG
KDRSNARATVHRLVADTPIQPIAHLTCVGNSTAEVVSTVYDYLDSGVRTFLALRGDPPAG
ETSWEPGPDGVASATELIHLIRTVEQRRCDAHPGEALRSAFKPLTIAVAAFPAGNPAAGT
TPAQEVERLLVKQAAGASFAITQLFWNAEVYASFVERARRAGVHIPIVPGILPATDPARL
RRVQDLTGIEVPEQLLSTLAGYQHQEQRDAFGAAFGSKLIHSVLEAGAPGVHLYTFNKAK
PVLDILSLMGVEPTAHHSPLLAR
>A0A412YZC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGVYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKNGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNIEQDLYWLKKKVEAGADYVVTQMFYDNQKYVAFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAIKCKDDKEARALGIEWCVNQCRELIAYGVPGIHF
YTVGAVENVKEVAAAVY
>A0A2E7X9Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSDASASTPSHKGPIRSRAEKATHRRLLDGMAYELIPLKNVHDQAGFLPPGSTVSVTCSP
AKTIDDTLDLCATFAEQGHTTIPHFAARMVEGEEHVDRIAKRVDEQGIRKVFVVGGDADP
RGPFTDAAGFLRAFLDRRPDIDVVGIGSYPDGHSTISEQALIDTLIEKQEMIAXAGLXGY
MATQMCFDAXTIRDWLSGXRSAGXTLPCHLGVPGAIDRTKLLTISIRLGIGHSARYLEKN
RTSVIRLLSPGGYNSNKXIAPLSAVADELDIVGIHCFTFNAVDTTEDWRQKSLRKLAPNG
RD
>A0A158G7U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia udeis|TrEMBL
MKPIELSFEFFPPKTQEGIEKLRATGAQLKMLNPKFVSVTFGAGGSTQQGTLDTVVEMMK
QGLEAAPHLSCIGSSKESLRAILGAYREHGIRHIVALRGDLPSGMGEVGELRYASELVGF
IRAEHGDWFNIEVAAYPEYHPQARSPKSDLENFVRKVQAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPKWIARRLESYGDDKEAIRAFGLDV
VTGLCERLVKEGAPGLHFYTLNGAAASKTICERLVLPKA
>A0A2D4Y9Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIKNANGKTLFSFEILPPLKGQHIQSIFDNIDPLMEFNPPFIDVTYHREEYTYKD
VGNGLLKKQIVKKRPGTVGICAAIQNKYNVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKSETYFKPEKDGHAYASDLVSQIEDLNNGKYLDEELLNTCATNFCIGVGAY
PEKHMEAPSLDSDIHFLKKKIKNGATYIVTQMFFDNKKYFDFVDKCRKEGITVPIIPGLK
PIATKKQLNLIPHRFHVDLPEDLIIEVVKCKDNAAVRQVGIEWCIEQSKELQNAGIPTLH
YYSMGKSENIKAIASEVF
>A0A3D1ID04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
CCGTTPDHIRELRALLESRPLRSHRHGGVALRSRETTELPQAQPSELSEKLGRKFVVAVE
LDLPRGLNLDRLLDGARRLKIAGVDVVNISDGARARLRMTPSAACATIQSRVGIEAMMHF
SCRDRNLLAIQADILGAHTLGIRNVLAITGDPANIGDYPSATSVFDVDSIGMVRILRRFN
EGIDLAGNPVGMRCAFTIGVAFNPLPMDRDLEWDRLRRKADAGANVVYTQPVFDERAIDE
ALDACRSVGLPCLVGVLPLRSQRHCEFMHNEVPGIEIPERLRRRMAEAPTEEDAQKIGME
EAMLLVERIRSCAQGLYLMPPFGNAGAAIPLVEVAKGSV
>A0A349B4I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MTRIGDLLANGPSISLEFSPPKDDEAEKQLLAVVDELAVIEPTFTSVTYGALGSTRERTR
DVVIELNRRHPFPTMAHLTCVGHTKDEIRELLDAYAEQGVCNILALGGDPPADAPPPGGD
FRYALELVELVHEHPGDFSVGVAAHPEKHPRSPSLETDRRYLAEKLAAADFAITQFFWSV
EPYLRLRDELAALDCDTPVIPGVMLFINVHSMRRMAEMNDAAVPDELWDRCLAVDGDPKA
VRLLGTEVCAALSRQLLDAGAPGLHLYTMNRSVAAIDLVRRLGLAPTAS
>A0A2G2G4Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robiginitomaculum sp|TrEMBL
MGNLRVSFEFFPPKTDKMRDNLWATIKKLEPLNPDFVSVTYGANGSTRERTHETVAKIAK
DTSMNVAAHLTCVGAHKDEISEIAQAYWDAGVRHIIALRGDPEAGIGSKYTPTKNGYAYG
SDLVEGLRKIAPFDISVSTYPELHPESRNWSDEIDNLKRKVDAGATRAITQFFFSPDIFL
RFQDKVLDAGINIPIIPGLMLQPNYNGIKRMSDMCKIHIPDWYHELFSGLDDEPATRQLM
AATTAAKLVAKLQKNGVQRFHFYTLNKADLTFMLCKTLGISPMGNK
>A0A256W9I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium 4572_112|TrEMBL
MKIPETLKQNKKSLFSFELLPPLKGRSIKEIYDTIDPLMEFKPPYINITYHREEVVYKKR
TDGLLEKKTIRKRPGTVAIAAAIKYKYRDINVVPHLICGGFSKEETENALIDLSFLGIEN
ILLLRGDPEHSTNRFVPEKNGHHNALGLINQVSDLNNGIYLDEELENSSPTDFTIGVAGY
PEKHIESPNDLSDLHFLKKKVEAGAEFIVTQMFFDNQKYYNFVNACRKEGITVPIIPGIK
PISVQNHLNSLPKTFNIDLPEALVKELIKCKDNSHVRQLGIEWAIAQSKDLIKNNVPVIH
YYTMGKPDNVYKIAKAVF
>A0A4Q5M2M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emticicia agri|TrEMBL
MAKVTEHLSNTQGKPVFSIEIIPPVKGSNIDDLLKSIEPMMELKPPFIDVTFHREEYILK
NLPDGGSKEIKIRKRPGTVGICASILHKFNIDPVPHVLCGGFTKEETEDLLIDLNYLGIE
NVLALRGDYARPYNSFKAKKDGHFYANELVGQINDMNNGKYLHEEAEYLNASNFCIGVAA
YPEKHFEAPDLDQDIENLKRKIAAGADYVVTQMFFDNQKYFDFVNRCRAEGITIPIIPGL
KVLATKKQLDVLPKLFYLDMPEAFRKEVMACENDKHAKQLGIEWCVQQCRELIDFGVPAL
HFYTMSKSDTTLAVARQVF
>A0A6J4U4I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Thermoleophilia bacterium|TrEMBL
MALLETVEHAVKGPIWDCRMCGQCVLHSTGMTCPMTCPKTLRNGPCGGVREDGNCEVVPT
MRCVWLKAYDRKERLPLLPSWRRHFDDLRPPVDNRLKGTSSWRNLVTGRDRETPDGWPDA
APHVAEV
>A0A2N2N6F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-5|TrEMBL
MTATPLSASPDDLVKKILMLKECVDAVNFTDNPSSTPRMSSLACSLIALQNGVEPVLQIA
ARDRTRMGLQGEVLGASALGIRNILCLTGDHPRLGPGPNGRMDIWDIDAIQAMWIIRRMR
DEAQFLDCREIKCAPQVFIGAAGSPYASTPLIQAMREEKKVNAGAQFMQTNLIYDYDGFQ
QYLEALERREVTRRVPILAGISPIRSIKAAYAMRQVPGVKIPDWLIHRMEASADPKEESV
QITLELIDKVKALPGVRGIHFMAVGWESIVPRLIKDSGLR
>A0A3N4TF64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. BIGb0102|TrEMBL
MSLFSQCLEQKRFCILVEYLCSKRDTLAVTQSLAGFPAMMTLADRVHSDEDPAPLELAQR
YSSEIEKLLHFSGKGRDIKEFEHFLDQAEQQGYHNLLLLTGDKLKNHNFGREIPAQRSRY
LESVSAVMAAKQRHVFNIGVAFNPFKYTEAERDAQYLKLHKKIKAGADFLITQLGFDLDC
LQHSQSFISQNYNEFPLIACVMPLTLKRAQFMVKNQVAGLVIAPHIVDVLECEYAADPVQ
AEANVYARCALQILICKHLGYVGVHLSACHKPQEQQKLEQFLKQFESWSLEACEKAWKDL
WKIDSGLELKPELSTFSKPVSQIQILKYKKMHLMHHIFFVSQAALGVGRFIFKANFWNKP
RPQHLLLKMEHWSKQQLVGCESCGHCRLDDTLYICPETCPKGLANGPCGGTTLDRCEFGD
RECIHSIKARLAKSIDQTEVLRSKLIPAISIETRYTSSWKNWFSNSDLN
>A0A3B1CPN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MSFKEALESGKFVVTAEVGPPKGTDISEMVHHIELLKGKVEAVNFTDNQSAVMRMNSLAG
CAIAVEHGVEPILQMTCRDRNRIGLQSDLLGAHALGVRSVLCMTGDHVTAGDHKGAKPVY
DVESVQLLRIVDSLNNGKDMAGNELKGGTDFFQGGVVTPEANPLEPQLIKFEKKVKAGAR
FFQTQAVYDIEKFREFMKYARNFNVKVLAGLVVLKSAGMANFLNNYVPGIKVPQELIA
>A0A1W1BBS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MFDQFCQTLCSDKPYITVEVNPPHGASLDSIIASISDSGVEDKITGFSVTDNPLAKLKMS
GVLSAIKLQQAFGKPVIATMSMRDKNKLSLQSTLLGANDFDIRCILALTGDPAKFSDQPE
VKGVLERDSTLLLSIIYHLNNGVDYSNKVLNPAPKPIYPFAVANSYARNMKSLQKRIVKK
LNYGARAIITQPIYDLDNAKELLELFEEAKSMSIRDTAKDAKMIIGQFPIVRARTATFID
DNVPGISVPKDIIDEMNLAKMDGEDREQEVGFALSKKIFDDMMSIHGKVHLMTHNRFDLC
SELIG
>A0A7J5NSB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides xylanisolvens|TrEMBL
VAAYPEVHPEAKSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEII
PGILPVSNFKQAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREG
VKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4P2R336|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
MRPMSRTRPEAPFLDAIRRSILVFDGAMGSLLYERGVFVTQNFEQLNVTRPDLVKRVHAD
YVAAGANVIETNTFGANRFRLERYGLVNEVRNFNLAGARIAREIAGGDAYVAGSIGPTGL
VPGVAKRDDLAAAAATFAEQAGALAEGGADLLVLETFRHLDEIKLAIEAARQAAPGLPVL
ASMTFDTSGVVADGSEPERVARTLRDLGVDLLGVNCGDGPQLSLAMAERMATAGLPLCVQ
PNAGLPRTVDGRLLYMATPEYFDVFARRMIQAGATMIGGCCGTTPEHVKWMAKSARMLRG
SAVPEVTSRPHVTMDAPTGSEPTPLGERSPLAAKIAAGKFVVSVEVNPAPGLSPESALSA
AKMLIDNGVDVVNVADGPRATARMTNLAFCSLLVQRYGIEPILHVCGRDRNLIGQMAHLL
GAHAIGIKNLVIITGDPPKVGDYPEATAVYDLDSIGLLHMASTMNRGLDPAGKPIPGGKT
SFLLATGLEPGAPDLDKELARLERKRAAGADIIMTQPVFHQDLLEKVLRRIEHLGMPVLV
GVLPLVSYKNAEFLHNEVPGMQIPEEIRERMRKVPAGPEARKEGVKIAREMLFSVRDRVQ
GAYLMPPLGRYELALEVLDGLKAS
>A0A848W038|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Silicimonas sp|TrEMBL
MSPTISYEFFPPRSLEASFRLWDTVSALQHTDPSFVSVTYGAGGATRQLTHEAVKTIGAH
TGLNVAAHLTCVDATRAETLEIADRYADAGVNRIVALRGDPPKESGAFRPHPDGFASSVE
LVGALAKTGRFDITVGAYPDPHPEAGAEDADITWLKRKVDAGANRAITQFFFDVETFFRF
RDRCVAAGIDVPILPGILPIHSWSGTQRIAQHCGAHIPPRLAQAFDTSERDGRTELLATA
VCTQLCSKLLDQGVEHLHFYTLNAPKITRDVVHALGLVPEATLEKVA
>A0A6M9FDY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPEVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETLADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3B0W8P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKSQQKHPQKFSLEFFPPRTEKGMEKLKNVIQELGTLTPEYMSVTYGAGGTTQERTLDTV
RYIQDHTSFDAAPHLTCIGADKESVTELLNTYEAMGVNRIVALRGDLPSGMMDPGEFKYA
SDLVAFIKEQRGDQFHLEVAAYPETHPQARNCAIGMKWFKHKVDQGADSAITQYFFNFDS
YRYFIDNCERNGIDIPIIPGIMPIT
>A0A6A1RMV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter guillouiae|TrEMBL
MSQLSQYFAQNQFCCLVEYLPSKQEVLPVATQLAGFPVCMTLSDRVRSDEDIAPLIAAQS
YPQQIEKVLHYAGKGRDIHDFNLFLKQAKQHGQQNLLLLTGDKLKQHHDGQGSHARTRYL
ESVNAVIAAQQQGGFHIGVALNPFKYSQAEKQAQYLKLHKKLQAGADYIITQLGFDLVAL
KQAHEFLIEENYTQKILACVMPLTLARAKFMLKHNVAGIVITPHMLEVLAQEHDSDQTEN
TYLRCALQILICQHIGYAGVHLSACHKADEQAILTSYIEQYRHLDLKQCQQLWTQLWQLK
TGNELRPAAVEKSKLSNLHQKVKYQFLDTIHSTMFNSSLVKGLGAYIFSANFWNKALAAK
LLLQAEYLSKHFIVGCESCGQCRLAETLYICPETCPKGLANGPCGGTHLDRCEFGDRECI
HSIKARLAEEVNQIQILKKQLIPTVPIEVRGTSSWKNWYVKQ
>B9E2G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium kluyveri (strain NBRC 12016)|TrEMBL
MNIKEKPLIFDGAMGTYYPRISKDPLPKCELANIYDRNTILKIHREYIEAGCMAIKTNTF
GANKVSLESDFNKVKEVIINGYEIAKEAAKDTEVLVFADIGPIPFLESMDLYEGYKEIVD
LFLELGAKYFIFETFSSDEYLREISEYIKGKDPEAYILMEFAVSPEGYTRVGKSGKKLIE
NILKIPTIDACGFNCFSGPYHLLQYIKTFNIGNETISVMPNSGYPTVIDNRTFFDNTKEY
FAQRMLEIAKQGVSILGGCCGTTPEFIRETVIKLKKLSKSEIVLKKQAEKIHTEKPVVKN
VLLEKINKGKKIIAVELDPPIDTEVDFFLNSARTLKEQEIDAITIADCPIARARVDSSLL
ACKLKRELDITTIPHMTCRDRNINATKALLLGLNIEGVNNVLVVTGDPIPSAERDEVKAM
FSFNSAILANYITNLNDTIFSSPFNICGALNVNSRNFNTELKRAKTKIENGIAVFLTQPI
LTEEALENLKLARRELTARILGGIIPVVSYRNACFMNNEISGIRVSEEIIKQYKDVSKEE
AVKLAVKISTDIAEQIYPYVDGYYLITPFKRIDIISEIINNIKAKNTITI
>A0A3B1E649|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MFDTLINKLQNDKYIALETTPSREPSFDNILDAIEKYQLNTKIDAFSTTDNPLAKLKYNS
LFAAVKLQQKFNLPAIATMSMRDKNKIALQSDLLGANDFDIRTILALTGDPIKMSDQPHA
KGVFEGNSQMLLEIIKSFNNGMDYSGKPFKIKPKQILPFCVINSYAKHFKSLENKMNKKI
QCGVSGIISQPVYNTQSAIKLLESFNTAKNDFKDQRAKTQLILGIFPITKLRTAQFLSSH
VPGINVPNNWIDTLTKASKISEDEERKVGMNLSHKLLKDIQKLHPKIHIMTTNKFDIAYE
LLD
>A0A3B0SWH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKVTDHIKKAKEKTLFSFEIIPPVKGRSIKELYGNIDPLMEFDPPFIDVTTSREEYIYID
KDGLLDKKLTRMRPGTVGICASIKHKYNVDTVPHVLCGGFTREETEYLLVDCHYLGIDNV
MALRGDAMREEKYFEPTKGGHPYALNLVEQIQNLNAGKYLHEVIETDDCADFCIGVAGYP
EKHLEAPSLKSDLVRLKEKVDAGADYVVTQMFFDNKKYFEFVEAAKEAGITIPIIPGIKP
MAIKRHLQLLPQVFRIDLPQDLINAVDACENNKAVRQVGIEWAIQQSKELKAAGIPVLHY
YSMGKSDNIQAIAKAVF
>A0A2N9YA67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beggiatoa leptomitoformis|TrEMBL
MTAINTLTVSCEFFPPRTEDGIIKLRQVQERLKALNPAYYSVTFGAGGSTQEKTYETVVD
IQIQSNIPAAPHLSCIGSTRDNIRQLLQAYQAKNINRIVALRGDQPSGWAGRLGDFNYAN
ELVEFIRAETGDYFHIEVAAYPEVHPQSKTPQADLNYFAQKVRAGANSAITQYFYNVDAY
LYFVDACQKQGIDIPIIPGIMPISNYEQLSRFSDICGAEIPRWLRKRLEPMHEDKTALQA
FGVDVVTHLCQQLINNGVSGLHFYALNQSDLTLRIANNLGLVT
>A0A314L6R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nicotiana attenuata|TrEMBL
MKVIEKIQEAAKDENRVVFSFEFFPPKTEDGVENLFERMERMVAHNPSFCDITWGAGGST
ADLTLEISKRMQNMVCVETMMHLTCTNMPVEKIDHALDTIKTNGIQNVLALRGDPPHGQD
KFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDVIPANGIATQEIYENDLAYL
KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQLGITCPIVPGIMPINNYKGFLRMTGFCKT
KIPEEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMDKSALAILMN
LGLIEESQISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTLGWDEYPHGRWGNAQN
PSYGALTDYQFMRARSRDKKLQEEWVVTLNSVEDIYEKFKDYCLGKLRNCPWSELDGLQP
ETKIINEKLGHVNTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSGEKL
NTLVENCKAFPYLTYMAVNKEGNWISNISQTDVNAVTWGVFPAKEIVQPTVVDPASFMVW
KDEAFEIWSRGWAQLYPETDPSRKLLEQVQSSYYLVSLVDNDYINGDLFSIFRDV
>A0A2L0FBK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum|TrEMBL
MVTKSKMERLLSERQFLVSAELTPPRHYDLEKLLKHARNMATCVDVVQINDHLLSQARCA
NMVVGHLVKQEGIEPVLQFSLRHKNRIALQGDLLGMAALGLSNIIVLGGYPCSIGSDPDA
KEVNDVDSNSAIQLTSRMTREGKLFNGDAIAPAPYFHVGTIDFPCGEQAIAGAMDRLTAK
IEAGASFIQVQAVFELASMRRWMAAVVERGLHERAHFIAAIFPFAGVDRLNFLQKVPGLV
VPDHLIERVRKSGDAEGESYRITLELIRGLRDVPGLSGIHMRSIGAEDWVPRLVDEAGLR
RAA
>A0A3R9I375|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLNKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHIPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A4T0SVL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia mellicola|TrEMBL
MKITEKLLAAEREDRLWWSFEFFPPPRFVDLSTTISAHSVQGMTNLVDRIERMRRLGPEF
VDITWHSGGRTAELTTELVKTCQASIGVETCMHLTCTGMPREKVINALEEAKKNGCTNVL
ALRGDPPRGQTEWYPHPNGFTYAADLVRHIRQEYGDYFEVAVAGFPEGNLQYKHSSDKDN
EIQYLKEKVDAGADLIMTQMFYDVDNFIDWCNKVREAGVTVPIVPGIMPIQTWNGFQKAV
QMAQTKVPQNWMDQLEAVKEDDAKVREVGTKLVSDMCRKILDANVGIRGLHLYTMNLERG
PKMILQELNLIPQTQILNPLPWRPSLTPTRRAENIRPIFWANRQKSYLSRTEMWDEFPNG
RWGDSRSPAYGEIDGWGPTINFKLDEAREIWGEPLKYDDVCNLFSRFCLNDLKALPWSDQ
PPARETSVIDRQLAMMNKIGFFTINSQPAVNGARSDDPVHGWGPKGGYVYQKAYLEFFVS
PDNLDKLISRIELNPMMTYYAVNRRGDLRTNTHSEGPNAVTWGVFPGKEIVQPTIVEAVS
FMAWKDEAFELGYQWSDIYEKGSTSQQLIKDIMDSHFLVNVVHNDFKNGQDIFKPFLDEI
ANESAIKDTTKN
>A0A428CWC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFHYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1W1DLV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKTSFEFFPPRTDKGKQTLAQVRQELSTINPEYFSVTFGAGGSTQDATLETVLDIQANDS
VSAAPHLSCIGSEKAKIIELLDQYKAADINRLVALRGDIPSGVRDIGDFRYANELVEFIK
SEYNDHFHIEVAAYPEMHPQAKNIQTDLEHFANKVKAGADAAITQYFYNADAYFRFRDDA
QKLGIDVPITPGIMPITNHTQLLRFSNMCGAEIPKWILERLKLYENDLTSLTLFGTEVVS
NLCQTLKDQGVDSFHFYSMNRTEPSLSIAKNLL
>E1MFD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobiluncus mulieris FB024-16|TrEMBL
MASGVDWVAPDAGGVLDTPGTPVAFTSVSRGANPKSSRNPTRPVRVSFELYPPRNPDPFS
QAWAGIDRLLDAHPDYVSVTFGTSNSTSASSQSVLAHALQRLGRPVLAHLTCVGKTRTEL
STTITEMLDIGVRDFLALRGDNPKGSVNWEPAPGEFSRASQLVTLLREVAAEYLGDARAI
SIAVAAYPAGTVSARTNAVAALAEKQSAGADFAITQVFYNADDYGALLDSATYQGVSIPI
IPGIIPFTDAARLQRLEGLTGVSVPSRLQAISEISDPEERFLEGLSATLDFVNDLIQAGA
PGLHFYTFNRPRPVLDLVEHLRSRGFTHVDEDSSSELLDLMNAAMQRFSP
>A0A3B1B4Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MTRDRLARMNFLGPCLSLLVTKFMESQKKFSPQFSFEFFPPKTDKGVEKLKLVRDQLGAL
KPKYFSVTYGAGGSTQQGTFDTIMSIRQAGFDAAPHLTCIGATRQSLRELLQQYIDNDIH
RLVALRGDMPSGMHTSGEFRYANELVEFVRTEFGEHFHIEVAAYPEFHPQANNAQNDLEN
FKTKIDAGANSAITQYFFNPDAYFRFIDDCEQMGITVPVVPGIMPITNFSNLARFSDMCG
AEIPRWIRKRLEGFADDTDSIKAFGEDVVTNLANQLLEAGAPGLHFYSMNQAEASMAIWK
NLGL
>A0A3B0TC07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKVIDIIKNREKTVFSFELLPPLKGNDAGRIYNTIENLIEFDPKYINITTHRDEVEFKEM
ADGTIVKRTVRKRPGTVAIAASIQYKYGIPVVPHILCGGFTKSETEHVLIDLNFLGIENI
LALRGDSIKNQHVFKPEADGHSNANELVQQISDLKQGKYLEQDLKNNTPLDFCVGVAGYP
EKHFEAPNSEQDMEYLKQKVDTGAEYIVTQMFFDNRFFYDFVKRCRDIGINVPIIPGIKP
INLKNQLTVLPKIFNIDLPTELVAELAKCKNNGDAKIVGTEWAIQQSKDLIENGVPSLHI
YTYGISDNIKEIVKAVF
>G4A849|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aggregatibacter actinomycetemcomitans serotype e str. SC1083|TrEMBL
MSYAKEIDNLNQHLADLNGKINVSFEFFPPKNEKMENLLWESIHRLKALKPKFVSVTYGA
NSGERERTHCVVKRIKQETGLEAAPHLTGIDASSDELRRIAKGYWDSGIRRIVALRGDEP
KGYEKKPFYAADLVALLRDVANFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMVVITNVKIPAWMSKMYEGL
DHDQTTRNLVAASIAMDMVRVLSREGVKDFHFYTLNRSELTYAICHTLGIRPGL
>A0A6I5NM94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. SIO4C1|TrEMBL
MTNSAATQFRAAVQAGDFLVTAEVMPPKGGDPSHMLAMARQLKGRVHAVNITDGSRAVLR
MSPLACAVLLQREGIEPICQMACRDRNQIALQADLMGAHALGIRNILALTGDPIKAGDHP
QAKGVFDFESVRLLQMIHRLNLGSDANSKALPDGPLDLFAGAAVDPQLRSWSGLQRRFER
KLAAGAQFFQSQLISDFDRLDKFMTQIAVGCNRPVLAGIFLLKSAKNAEFINRCVPGVQI
PPATIDRLARAADPLQEGIQIAAEQVQAARELCQGVHLMAVRREDLIPQILDRAGVRPLT
PLHAAEATG
>A0A3P3ZK52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania braziliensis MHOM/BR/75/M2904|TrEMBL
MSGLISDAIAAEDANKWYTSYEFYPPRSEKAEENFMKVQIPNFMRQSPVFLDLTWGAGGR
TSETTMRLCKDLQNAYPDTPINMHITCTNMSHDLIKETLDFAKEHGIRNILALRGDPPRG
DEFQSNPEGFTCARDLVRYIHATYGDYFCVSVAGYPEGHPSRIAEDGTILDEDHQKELEY
LKEKVDAGASVVITQLFYDASLYVKFVKDCREMGITVPIIAGLLPITTYAGFTRMVSLCK
TRVPGDVKKRVEELKENPEALKEYGVEQCVQMIERIRASGLDYHHLHFYTLNSSAQTFQV
LKRLNALVE
>A0A7S1GWM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hemiselmis andersenii|TrEMBL
GSSKKKKTEAGVALVEIPLSERTGLSAKVARIWEGRLNGGMSKASPTGPEDFVVSVEVNP
SPGLSTDKPVSIAKMLREGGVDVVNIADGPRATVRMSNTALGEVIQRELSMETIIHVCCR
DRNILGLMSDLLGNYSRGLHNLVVITGDPPKMGDFPKATAVFDMDSVGLLKMIHGLNTGL
DPAGNQFAGQAKYFCATGAEPGAVDYEREIRRLKEKIAAGADMVMTQPVYDASVMRRFLD
DVASFPKPVPILLGLCPLVSSRNAEFLHNEVPGMSVPQNIRDRMASVG
>A0A0P1IN63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cognatishimia activa|TrEMBL
MTAPKISFEFFPPKNLEASFRLWDTVQVLAPMCPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLNVAAHLTCVDATKEETLKIANDFAAAGVNEIVALRGDPPKGSDGFKAHPDGFGSSV
ELIEALSDTGKFKIRVGAYPEKHPEAKDQAADIAFLKAKIDAGAEEALTQFFFEPETFLR
FRDACAKAGIDAPIIPGILPIENWKGVRSFAKRCGTNVPTWLEDAFEKAERDGREELLAT
ALCTELCDNLRTEGVDSFHFYTLNRPELTRDVCHALGVTPATKLENVA
>A0A0V9UHS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus pyridinivorans KG-16|TrEMBL
MDRLGSARSGRIPFSVEFSPPRDAEAEGRLWRAVRTFERLGPAFVSMTYGAGGSTRDRTV
RVTGRLAEETTLLPVAHLTAVGHSIDELRAMVGAYADRGITNILALRGDPPGNPLGEWEK
HPEGLEYADELVRLVRDLGDFHVGVASFPEGHHRSPDLDHDTRYLVQKLRAGAEYSITQM
FFDVEHYLRLRDRVVACDAEQGLKPIIPEIMPITSLRSARRSLELSGSHLPPVLEERLRR
AAGDGPEENRAAVREVGIEVATEMCERLISEGAPCLHFITLNFARATGEVLDRLGYELEA
PAAVQPA
>X6FGH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNHC209A00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLEPLQPKFVSVTYGAGGSTR
ERTARTIGRILKETSLTPAAHMTCVDAARHQVDAVIQEFTDMGVKRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEVAGS
AAA
>A0A0D2XQM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936)|TrEMBL
MLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIAELTCE
MVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDKWTAAD
GGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASFIVTQM
FYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDALEPVKN
DDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERPLQQAL
PWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDAYGIGL
TGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIELNKRG
LLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHPDLTYY
AVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDWAHCYD
MSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESVGNGAV
DTEPIANGTAATAVAN
>A0A5C5X6F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassoglobus neptunius|TrEMBL
MRIKDVYEKSPFGISFEIFPPKTEAGDVALLEGLQRLTARSPDFISCTYGAGGSTQDRTL
ELCEMIQRDFQIPATAHFTCVGSTIEQLNNWLDAADLRGIQNFMALRGDAPAGSDSFEAV
SGGLKYANELVELIRSRFPDVGIGVAGYPEKHPEASTMEFDLDNLVRKVDAGADAIFTQL
FYHNENFFRFRDELERRSVSIPVVAGIMPITEFARIKRITAMCGAIIPDGLAGQLEAVQD
DAEAQRAIGVDYAIKQCQQLVDEGVRGIHFYVLNKSEACERILDAVQIPRSV
>A0A1I1AGY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella sp. OV330|TrEMBL
MKPDFRTALSQRPLVGDGAMGTYLYQLGFPIGVAFEEYNLIKPEMILEVHRRYAAAGAEV
LETNTFAAQHGNLVRFGLEKRTADINAAGVALARQAGGDAAYVLGAVGAIRAGQRKNART
AEITRDYEEQIGALMGAGADGILLETFFELDELMLALRVARRLGDLPVVCQFAVDDPAVT
RDGVPMGEALRRLKDEGADVVGFNCRSGPNGILRAVQNIPLDLGLPLSAFPNAGLPDYED
GKVVYSASPAYFGENARAFADNGVRLIGGCCGTTPEHIAEIAAALRGYAPDETESSRPAT
AAEVRVAPSRQPSESAVGGGEEPANIVQLVRERHTVIVELDPPKDLDIGRFMDGAAALRD
AGADALTMADNSLAVTRMSNMALGALVQERVGIRPLVHIACRDRNLIGTQSLMMGFDALG
IDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIKMIKQLNEGIAFSGRALKQKAKFVIGAA
FNPNVKHLDKAVQRLEKKVAAGADYIMTQPVYDAELIERIAEATKHIGVPIFIGVFPLAS
GRNAEYLHNEVPGIQLSDAVRERMRGLEGAEGKAEGIAVAKELLDAAMKHFNGIYLMTPF
LHYEMTVELTRYVKEKSGVHADNCGCASCPTNDYQVK
>A0A837SYC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. lactis|TrEMBL
MTSNSKILSFEVFPPTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFKFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAA
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>A0A7C5TLT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiales bacterium|TrEMBL
METQRRFPQEFSFEFFPPKTAEGEARLREAWEALLPLRPAFFSVTYGAGGSTRERTYETV
LALRQATGVEVAPHLSCIGSTRAAIRELLERYRAAGVRRIVALRGDLPSGMVEPGELRYA
NELVAFIRETTGRHFHIEVAAYPEFHPQAAGARADLEHFRRKVEAGADSAITQYFYNADA
YFRFVADCEAMGLEIPIVPGIMPITNYAQLARFSDACGAEIPRWIRKRLEDYGDDLASLR
AFGADVVAELCARLLEAGAPGLHFYTLNRAEPVLAIWERLGLPRADAPAKAGR
>A0A1Q7V8Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonas sp. 13_1_20CM_3_60_15|TrEMBL
AQTLDAFGADVIGLNCSVGPQIILDAIEKMAPVTRRKLSAQPNAGMPRDVSGRSMYMASA
EYMATYAHHLVQAGAKIVGGCCGTTPEHIAAMVEGVRPLSPRQARLPMKDRRHSHPDVPP
ENPGVEPVPLAERSKWGRKIATAEFVTSVEIVPPRGVDAAKMIRDTAALRDAGVDAVNVP
DGPRAQSRMGALLCSILIEQQVGIETVIHYCCRDRNLLGMLSDLLGASAVGLRNLLLITG
DPPKMGPYPNATAVFDIDAIGLTNLVSNLNHGLDPGGNAIGQPTKFTVGVGVNPAAIDPA
QELKRFEWKVEAGAEYAITQPVFDVQQLEKFLSTIDHVRIPIVAGIWPLVSLRNAEFLAN
EVPGVVVPAKIIERMRVASAKSKEHGVAEGIAIAREMLERVRPHVQGVQVSAPFGKVELA
LEVFRDTLSRANLRAPTAAQPA
>A0A260B880|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. 06-221-2|TrEMBL
MSEDSVRGRSSRGFVTRTPSIVDRLRTEPEARIPFSVEFSPPRDEAAEARLWRAVREFEQ
LQPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSVAELRSMVGSYADRG
ITNILVLRGDPPGDPLGEWEKHPEGVEYAEELVRMVRELGDFHVGVASFPEGHHRADDLE
QDTRCLVGKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSV
RRMLELSGTTLPSHLDEKFTRAAGSGAEEDKAAVREVGIELATNIGERLIAEGAPGLHFI
TLNFARATREVLSNLGLAAARV
>A0A2R7Z379|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides currus|TrEMBL
MVRLLEQARYEVLPTATTEDKVLQHLPRDRAITVTASPSKGLAATLDLSESLAGHGYVVV
PHLAARMISGRTELAEIAERLVGKGITSVFVPGGDAEAVGDYPDALALLEDLQVLGRPFT
HVGITGYPESHPSIHDDLTVQSMWDKRRHATHIVSNLTFDPAGVRDWLRRLRARGVTMPV
LLGMPGPVERTKLLGMATKIGVGESTKFLAKNKGLFARLAAPGGFTGESFLEKCAPALGE
EGAFVEGLHVFTFNQVAETEAWRTQLLEDLRS
>G9ZTS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus parafarraginis F0439|TrEMBL
MSLTALFKDKTVFSLEVFPPKKDSPKEAILPTLQQLQAINPDFISVTLGAGGSTHSSGTV
QITDLIQNQLNIPAVAHVPGLYQTKEQVLNLLDHLAENNVKNILALRGDRIPGKEPAGVF
NHANELISFVHEKRPDFSIASACYPDCHAEAASFVDDIAHLRQKVDAGADHLI
>A0A1E4TAE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tortispora caseinolytica NRRL Y-17796|TrEMBL
MKITQKLETASKPSYSFEYFVPKTTQGLHNLYDRMDRMYLLGPQFIDITWNAGGSDGSHL
TPEMVATAQSIYGLETCMHLTCTRMPAEKVDEALDAAYESGCNNILALRGDKPDENDMQD
GEDHFTYAVDLVRHIRSRFGDHFDIGVAGYPEGHDEQDDSSLLMQHLKDKVDAGASFIIT
QMFYDVDRFLTWVQECRDAGITVPIIPGIMPISTYAAFIRRASWCKVVVPDYFMQAIEPH
KDDDAKVRDIGADLVADMCRKILAAGITHLHFYTMNLEKATCMILDRLGVTPEVDAVNPL
PWRQSLARNRRSENVRPIFWKNRKLSYIARTQDWDEFPNGRWGDSRSPAYGDLDINGVAF
RLVTSQKAAQQWGEPKTIGDISALFVKYVKGELSSLPWSDSPISPEVNCIQEQLIELDQR
GLLTINCQPAINGVPSSDPVHGWGPKNGYVYQKAYLELLLPPDVVDQLIARVNQVNSKQN
DVVTYYCVNNNGDLRTNSVDDGPTAVTWGIFPGKEVVQPTIVEMTSFMAWKDEAYRLAGE
WAKCYPTSSPARALIETIAESWCLINIVHNNYFDAMAIFDLFDGISALPTGTVDA
>A0A371XGR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium denitrificans|TrEMBL
MSQSRFSRLPDLGDRIKVSFEFFPPKSDDMETRLWETVKRLEPLNPHFVSVTYGAGGSTR
ERTARTVGRILGETTLLPAAHLTCIDATCEEVDGVIRQFVDLGVKRFVALRGDPASGVGT
RYQPHEGGYANGAEMVAAISQHGSFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDIYERFVERVRRAGIYIPIVPGILPVHNIKQVGNFSARAGAHVPAWLLERFE
GLENDPQTHMLVAAAVAAEQVLDLIERGVGDFHFYTMNRADLAFAICHMIGVRPQHALSA
VAETTSAAA
>A0A7W7PNE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseostramineus|TrEMBL
MALGTASTRTDRARTVRDILAAGKTTYSFEFSAPKTPQGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCETPVIPEVMPVTSVKMLERLPKLSNAAF
PDALKERILSAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQAWTGRTGVRHTA
>A0A1Q3TCD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium 54-19|TrEMBL
MYNPLLERLDKGVMLADGAMGTILFDRGIPYTVCYEELNVTRPELISEIHRSYIQAGAEI
IETNTFGANRFRLAKFGLEDKVRLFNLKAAKLAREVRDISGEPVLVAGSVGPLGQTRGPA
LQPDAMRAAFREQIEALMEGGVDFILLETFYDYQQMVHALSVAKTITDLPVVAQMTFSEE
GHTFSGHTPLEAVTMLKARGADVIGLNCHVGPQGSLSVLEQLSAAGPQFPYLSVMPNAGT
PERIDGRMFYHASPEYFASYVPQFVEAGAKIVGGCCGTTPAHIAAMRAALDKIRPETATP
HHFTVQAVAEMFAPPHSETVENGTALEKTIEKVNRVEPTNLAKTLAAGKFAISVELIPPK
GIKPIKMLNAANQMAELGADTVNITDNAMATVRMSSLGCAMLVQQSVGIEAIVHYTTRDR
NLMALQSDLLGAHANGIRNILALTGDPPRMGSYPGASGIWDVDAIGLIDILSKLNQGSDL
NGTSIGSAANFNIGAAFNPTATDLPLEIERLRRKLAAGAQFIMTQPVFDPALLRDTLAEV
GEIKVPVLAGIMLLHNYKHAEYMYHEVPGIVVPDAVLKRMQNAGEKGMQEGLKVAIEVVE
QIHSLIQGVYIMPSHNKYEASAELVKLLRS
>A0A847KWE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter sp|TrEMBL
MTFQTTVDREASRQKPRVSFEFFPAKSEKSMGALLAAAEEIAPVKPAFFSMTYGAGGSTR
DRSLEAVEKLVNLGSVPVAGHLTCVDASRETVDEVARSYLRAGVKHIVALRGDSSEVGKP
FTPHPDGYRNAADLVAGLKKIADFEISVAAYPEMHPEARSPEADLDNLKAKIDAGATRAI
TQFFFEAETFLRFRDRAAAVGITVPIVPGILPVASVTQAWKFAEMCGAHVPDHLRTMFDG
LDEQPSVRHLVTTAVAGQMCLELQKNGVDDFHFYTLNKATPSLAICRLLGVS
>A0A7L5BD27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium oryzihabitans|TrEMBL
MIMKRTMHKLPDIATSSIIHASIEASPTQVLGPASLAGLFPQGVRVYLTDTGAASQARLV
DAASHLRELGYNPVPHLAARRISSRTDFEEQVKRLAGEAGVSDVLVVGGGVDRPAGPFVS
SMDMLSTGIFDRCGINHIAIAGHPEGSPDFSEETAMAALRLKRDFGERTDATMRIVTQFG
FDPARFITWAEGLAASGIDLPVHIGVSGPAKITTLLKYAALCGVGNSIAYLKKNALSLTT
LAKGHSPESIVGPIERHWQANPKGPIRQIHVFPFGGLQNSADWLVGRGSWPYEKDGSASP
GSMAV
>A0A1C4BLD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus enclensis|TrEMBL
MKPLKESLKERILIADGAMGTLLYSYGVDRCFEELNLSHPEEVYKVHRDYIEAGSDIIQT
NTYGANYEKLSRYGLEDSVKEINTAAVRLAKKASGGSAYVVGTIGGIRAIKQNVSLEEIK
RSFREQLYCLLLEGVDGILLETYYDFEELMTVLKIAKRETDLPIIAQVSLHETGVLQNGM
KVKEALHQLEFSGADVVGINCRMGPYHMVASLEEVPLPKSSFLSVYPNASLPNYEEGRFY
YSAEPGYFGDISNELRSQGARIIGGCCGTTPDHIRAVAAKLKSRVPITEKKVKLTKSVEI
VSRPISEKLLHHKVNEKMTVIVELDPPKHLDTDLFFQGAQALKEEGIDALTLADNPLASP
RVSNEAIGTMVKEKYDISPLVHITCRDRNLIGLQSHLMGLHTLGIHNILAITGDPAKIGD
FPGAASVYDLSSLELIELIKQNNEGISFSGKSLRQKTQFSVGAAFNPNFRHMDASVKRLE
KKIKAGADYFISQPVFGVEEMFQIYEATRHLNTPVFIGIMPLLSSRNAEFLHHEVPGIKV
PEATRLRMREAGKDPIHSRAAGMEIAKELLDTALTLFNGIYLITPFVRYDMSIELLRHMK
EKAGIEKEVPYGRHII
>A0A7W8EQS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudochrobactrum saccharolyticum|TrEMBL
MSSFGQQRRSESAHPIRVSFEFFPPKTEEMEDRLWETVTRLAPLNPAFVSVTYGAGGSTR
ERTNKTIARIIKETSITPAAHLTCVDATKEEVNSIVRSFASLGVTRFVALRGDPASGIGE
VYQPTPGGYQNGADLVAGLKSIANFDISVSAYPEKHPESPDFATDIEMLRRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIIPGVLPIHNFKQVANFSKRAGTRIPAWLADRFD
GLENDPQTHMLVSAALAAEQVNDLIERGVNDFHFYTMNRSDLAFAICHLLGVRAPVAA
>A0A643GHU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oryzomonas sagensis|TrEMBL
MTVLDKLTTEILTGDGAVGTMLYARGIGLDSNFEHLNLVRPALVLELAREYAAAGAQVIE
TNTFGANYTKLAAIGLGHKVGEINRAGVRIAREAAGDGGILVAGSVGPLVRMKGEERELT
PDAMEGHFRVQCTALAEGGVDLFLLETFGSLEQLVAAVRAARETGLPVCASMAFLEGGRS
GDGTTVEAFCAAVEAAGADMLGANCGAGPLELVKVVRRLAALTAKPISAYANSGFPEYHE
GRYIYRATPDYFAAMADEMAAAGANLIGGCCGTTPDHIAVLARTLAGKRPAPRHPAASRT
AAGAQPGSRPDRPSFLDPWGCRKVIAVELDPPKGMDCRRIIESSRRLKEAGVDAINLAEN
PLARPRMGNIALGSIIQREVGIEVIIHITGRDRNLIGMQSDLMGASLLGLHTILAVTGDP
AAMGDHAGATSVFDLHSFTLIKLLSDMNRGVNAIGNPIGGGTGFTIGAAFNPNTKNMAVQ
AERLRKKVANGARFAQTQPVYDPALFLEALDQTRDCGIPLLPGIMPLVSERNALYLHNEV
PGITVPDAIRARMKGLEKEAGAREGLAIAKEFIDATFTAAGGYYLIPPFGKCELALELID
YIHAREREQG
>A0A1V5CAU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophorhabdus sp. PtaU1.Bin002|TrEMBL
MLKNRFREILEKREQFVYTVELVPGRGSKGKTHDDVLDLANKASQGGLIHAMSITDNPGG
HPALTPGVLGVEIARMGIDPIVHFTCKDKNRNEIESILYGLDRIGIRNLLAMTGDFPLYG
FEGKTKPVFDLDSVQLLHLITKMNEGLQIDARAPGGGRILPPTRMFKGCAVSPFKQLESE
TLAQYFKLWKKVQAGADFVITQVGFDARKFDELLRYMRHLDIKVPVLGNVYILNFPVARV
MNRNAVPGCVVTDQLFRICEEESKAPDKGKTARLIRAAKLIAVLRGIGYNGVHIGGPNLK
YEDIEWVIGKSIELSGIWPSLVSEFDYPQPGGFYLYEKDNNTGLNADNLTGRKSSPGKST
GYALMRFFHHLVFAADAPFYKPVCSFFKKVNGTRLEGVLTELEYWIKFVSSGCRRCGDCA
LADIAFLCPQSQCPKFLLNGQCGGSSEGWCEVFPGKRRCIFVRAYDRLKAFGEEGSLRGT
YIRPRHWELDQTSSWANYFLGRDHNVEKCNGKPQGRP
>A0A6L9VY85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus saxobsidens|TrEMBL
MHPEGRKPGAAGRVTWATPVPSAGVTRTVRELLATERPTWSFEFFPPKSPEGEAQLWTAL
RELERLRPSFVSVTYGAGGSTREGTVAVTERIAAETTMTPLAHLTAVDHSVAELRHVVSR
LAAAGVRNLLALRGDPPGADPQSDWVAHPDGLQYASELVELIRSIGDFSVGVAAFPERHP
RSPDFDSDVEWFVAKCQAGADFAITQMFFRAEDYLRLRDRVTARGCEVPILAGVMPVTNV
RQITRIVELSGQAFPAELAERFAALDGEGPEAKAAVRALGVEVATDLCARLLEEGVPGIH
FITMNRSTATRDVFTNLVGPDGDVRG
>A0A3R7S6W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaera sp. TMED24|TrEMBL
MSRIDQMFSERGPTASFEFFPPKDGEAWDALFAGXSAFEQLQPSFVSVTYGAGGSTRART
HDLVVRLRSETSLLPMPHLTGRGHTKAEIESILERFAESGVDNILALRGDPPKDGDLGPG
DFPHAIDLVRFIQSFNESGGHPNGGFAIGIAGYPEGHHETPNLLTEMDHFRAKVDAGADF
AISQLFFDNRRFLDWRDRCSMAGIQIPLVAGLMPITSAGGMRRMAELAAGTLIPARLLRG
VLDREADPEMVEAFGVLWATEQSRDLLDHGVAGLHYYTLNRSRAARRVYETLGIRDSRSF
LSGS
>A0A533T8I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium sp|TrEMBL
MLVKDILNAAVKPVFSFEFFPPKRDEDWETLFETIAALSPLNPSYVSVTYGAGGSTRSRT
HDLVTRIQQETGLTVVSHLTCICSDGDETGTILENYQNNGIVNVLALRGDKPAGVASIDE
AIKDFPHAIDLVRFIKTNYPAIGVGVAGFPEGHPETPNRMKEIEYLKEKIDAGADYIVTQ
LFFDNRDYFDFAERCAIAGITVPIIPGIMPITTKKGMIRMSELALGARIPAPLLSKVLNA
ANDTEVASIGIEWATSQVQELIDHQIKGIHFYTLNMADATLRIFNNIHQ
>S5XYS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus aminophilus JCM 7686|TrEMBL
MPYALEITGKDIGAIEALHGLLPAGTEINIAFLGNESHDQRIRVAELIRQAGYEPVPIIS
SRRLTSVADGDRLIAGYLAAAAPARFMFVGGDPKAPAGPYRDSLALLGSEVLARHGITRV
KIAGYPEGHPRIAPELLWQALRWKSAFLSERGVDFEITTQFGFDAEAIVRWITELRQQGI
DALVRIGIPGPTSAGKLLRFAGQFGVGASAAILRRYGISLANLLDPVGPEAFLDRLTAAM
AGKDLGRTAIHLYPFGGLVDGVAWINGALARGELPIRQG
>A0A1E9GF13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HMSC073F11|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDMVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>C5D741|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. (strain WCH70)|TrEMBL
MGLLEDLQERIVIADGAMGTLLYSHGVDRCFEELNLSKPEDIIHIHEAYIAAGAEVIQTN
TYGANYVKLARYGLEDEVPSINRAAVRLAKKAAGNKAYVLGTIGGLRSINKSAVSIEEVK
RTFREQLFVLLNEDVDGLLLETYYDLEELETVLAIARKETDKPIIAHVSLHEVGVLQDGT
PLSEALARLEQLGADVVGLNCRLGPYHMIRSLEEVPLPKKAFLSAYPNASLPDYRDGRLI
YETNTDYFKETALAFREQGVRLIGGCCGTTPKHIEAIANALTDRTPITEKVVKQRHVPIS
IQTNEPNAAPPLQDIVRKRRSVIVELDPPKKLGIAKFLEGAKALKEANIDALTLADNSLA
TPRISNMALGSIVKEQLGIRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKI
GDFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKSLGQKTNFSIAAAFNPNVRHLDKAVER
LEKKIQCGAHYFITQPLYSEQQIEEVYEATKHLETPIYIGIMPLVSARNADFLHHEVPGI
TLSDEIRSRMAACANNPVQSAREGIAIAKSLIDAAFDLFNGIYLITPFLRYEMTVELVRY
IHEKEQAAQERKVLHG
>A0A7U7I7M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas carbonaria|TrEMBL
MSQDRRYSFEFFPAKTEAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTVATVLQLD
SEVKVSTAPHLSCVGDSKAELRALLTQYQEAGIQRIVALRGDLPSGMGMASGELRYASDL
VEFIRAETGDRFHIEVAAYPEMHPQARNLEDDLANFVRKVKAGADSAITQYFFNADSYFY
FVDRVQKLGVDVPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDARSIQAYG
EQVVTEMCERLLQGGAPGLHFYTLNQADPSLAIWKNLKLPR
>A0A382I7X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MSKSTIQKNNFKATDLNLDGFHNDCKVANINLADLGEKNMSLNMKNLLTHLHHPHSVKDY
QGDEDPSTVKISEYWGKTPKQLKNPKISFEFFPPRSDAAKKSLKEAHRKLSSINPEYFSV
TFGALGSSQNATFDTIVNLLKDTKIPITPHLTCVGTNKKQVTNLLDEYIIQGVNQVMILK
GDAPNAIVKKGDFEYANEMVKFIKENYENIDILVGAYPEKHPHSNCVGKDIDFFVDKVNA
GATRAVTQYFYNIDAYFSFVDEVQKLGVDIPIIPGIMPITNYDNIINFSTNCGAEIPSWI
LNRLKLYRNDAESLEEFGEDVVSEMCLKLKAGGVKNFHFYTMNRVEP
>A0A382BGX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKISYEFYPPKDLDYKKVVDEFSRIRDFGPRFISITYGALGGSQKKSIGLIKAFKENTDI
DIAAHLTLVGKSKDELSVIVDDFKSLGVNKIVAIRGDSPEGKFKSHPNGFVNTTDFVEFL
VNENMEVFVSANPEVHPESESFEFDLNLLRQKTLAGSNQAISQFCFEMKAYKKLINAISE
NNIQNELIAGIMPIYNIQNLCNMAERCGTKIPKEIVRKFSNNPADNEKAAIEICIKQLED
LQAMGVNSFHFYTLNQSTLLRKIFDEIGV
>A0A838G089|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MRSKRRRQSLAPLLRDARLEVLPTPTAEQRIIENVAAGRTITVTASPNRGLEATLELAER
LAGSGYRAVPHLAARMVSGRSELTEISERLAAAGIDTVFVPAGDADPIAGDYSSAVDLLE
DLTALGSPFGHVGVTGYPESHPTIGDDVTVQSMWDKRRYATYIVSNMCFDPGALRHWIAR
IRKRGITLPVLVGLAGPVERTKLLAMATKIGVGESTRFLTKNKANVAKIASPGYSPERFL
DKTAATLTAPESLVTGLHLFTFNQVAEVERWRQRLLTAEDPSLVG
>A0A8F6H924|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus velezensis|TrEMBL
MGLLQDLKERILIGDGAMGTLLYSYGIDRCFEELNVSKPEEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVRIARASSDGAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALRSIADLGADIAGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTEKEVKIRREEEVI
SVSNERTEPGLNEIAAQKRSIIVELDPPKKLNFDEFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLKTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A7V9KU09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MAQGLPSRLPRRGVSLSQALASQGRSFSFEFMPPKDDVGERALWTAIRELEPLQPTFVSV
TYGAGGSTRDRTVRVTEGIAAETTLLPVGHLTCVGQSRAELRSIIGQYADAGVRNVLALR
GDPPGGPGQPWRRHPDGLDYAVELVAMIRCLGDFSVGVAAFPQIHPEAADPNGDARVLAA
KAQAGAEFAITQMFFDAVDYFALVERAASFGAHIPVIPGIMPITNLSQVSRFATLSGRPL
PATVVDRIERVGDDPAAVRAVGIEIASELSDRLLDGGAPGLHFYTLNRSTATREIFQNLR
VPTG
>A0A382D356|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MIEYQSLFHKKLLEGNFVYTAETTPPDSSDQEILLKKTKPLKGIADAVNLTDSPGAKAHM
SSLTAAIILVQNDIEPIWQLTVRDRNRLALQGDLVGASALGVHNILCLSGDDPKNGDQPE
TTVVNDIDSLTLVETADMMREKKQFPSGRLIEPAPKLCIGGAEVPTEGKPDPEKILNKIK
MGVNFFQTQYVFDEILLKEYMKVLEDAGILEKTFFIIGLGPFASAKSAKWMNDNLFGVDV
PDQ
>A0A382WAH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
VKKISENIVTHGTTIEPLANKMGVSFEFFPPKTPQLEKSLWCSVERLAPLNPVFVSVTYG
AGGSTREKTHKIVTRLQNKMDIPAAAHLTCVAASKAEVNRVARRYWEAGIRHIVALRGDP
PDGQGKYVAHPEGYNNASDLVRGLKQIGDFEISVAAHSEGHPEAKSIEADIENLKRKVDE
GATRGITQFFFQPEHFLRFREKTQKAGLSIPIIPGILPVTNFSQVRRFSKVCGASIPHWL
STLFERLDNDP
>A0A381TGM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MEILTTISDSFESDRFMEPADDLQENIEQDTTWSMEILPHNIAEVSLIPEFINEIYITMI
PGATCLEAIEAAQKIQAVGKQAVPHIAARSFTGAEDLEECLSGLEAAGIERALLIGGGYS
EPAGKISCVMDMLKTGLFAKYGINAFDFAGHPEGNPDDPNSAVHMLEKLRWAEEQGASAR
IVTQWSLDTECTNAWISGLREKGVNNPIHLGIPGPSTLKTLMRFAKICGVKASTTVLRKQ
GLNLSKLMFVNKPDKIIEELRGYDQLHLFPFGGIERSSAWLTEWQTKSYI
>A0A858R886|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium B3|TrEMBL
MSLAELLDATTDPTALVTTPSGLSVSFEFSPPKTEKAHENLWAAIHRLAPLKPSFMSVTY
GAGGTTRERTHATVTEIQAKTGIPAAAHLTCVGSTREEIDEIARTYWDAGIRHIVALRGD
PPLKADGTGGLGGLGYEPHPGGYAYAADLVEGLKRVADFEVSVACFPEIHPEAPSADIDL
DNLKRKVDAGASRAISQFFFDPAVFLRFRDKAADRGIDVPMVPGIMPILNFTKTAEMGRK
CNTYIPRWMTNLFEGLDDSPETRHLVAATVAIEQCRYLAKHGVKDFHFYTMNKADLTVAL
CHMLGVRAKAKVVA
>A0A7L2IGP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Semnornis frantzii|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTRDDITRHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEEDLKYLKEKVFAGADFIITQLFFRSETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLQVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTSYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPVVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A381NQJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MNRNQKEFNIKKLLNNYSIETTPNVYEKYGKFSDLISTDNAVYVTYLPDENSSRVINTAK
KLTNEGFDVIPHLPARTIKDNNELEKYIGDLSEKAGCNKILVIGGGSNQKGNITSSLDIL
KTDLLSKYQFKEVGLAGHPDGNPDISEEELDKAIIEKNEFVKNVDYKAYLATQFFFEVSS
LEIWEQKLNLHNNKLEIHAGIPGPATLKTLIAYAKSCGIGNSIRFLSKQAINITKIMKTR
TPDKLIADLADYKEERPNSKLAKLHFYAFGGIKTTSEWLYDVINSNLEINSKNEFKIIEK
>A0A7V9KT30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
DYAVELVEMVRSLGDFSVGVAAFPQIHPEAADPDADARVLAAKARAGAEFAVTQMFFDAA
DYFALVERAASFGADIPVIPGIMPITNLSQVSRFAALSGRPLPRTVVDRVARVGDDAAAV
RAAGIEIASELCDRLLDGGAPGLHFYTLNRSTATREIFQNLRVPTG
>A0A0D5LRH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Martelella endophytica|TrEMBL
MSELNPSRERAIGFSFEFFPPKTPEAEAGWWRAVQALTAYEPEFVSVTYGAGATSRAPTF
AAVKRLLDETPLVTASHLTVVKATKAEVDEVVHSFRNAGVKRFVALRGDAPGGVGAAYQP
HPGGYENGAALVAGLKAIDDFDISVSAYPEKHPESADRAADIAMLKAKADNGADRALTQF
FFENDTFEDYLGDVRRAGIEIPVVPGIMPVQNIRQLRNFAGRCGAIIPDWMARRFEGYED
DATAHFEIAADLAAEQVLDLQKRGLTEFHFYTMNRSKLMEAVFERLGIGPRIAGGVAGAE
LRSPAV
>A0A142JF09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus nantongensis|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVRAGADSAITQYFYNADAYFRFVD
DVRALGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A4Q2Y547|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MHIRDILSDSKPSLSFEFFPPRSAAAWEDLYQAIRELEPLHPSFVSVTYGAGGGTRELTH
DLVVRIKQTTTIPPVPHLTCVGHSEEEVLDILRRYAAAGVSNILALRGDPPKDRPDYDWS
ESGFRHAADLVRFIRKFNESGEHPDPRGFGIGVAGFPEGHPATPNRVDELDFLKAKVDEG
ADYICTQLFFDNHDFIDFRDRCAIAGIKIPIIAGVMPVTSLSGMKRMAELAAGARYPAKL
LRALERAKSNPEAVERTQQLGGVAG
>V8IH14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pseudopneumoniae 5247|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQILDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A3N1T0M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CEV 2-1|TrEMBL
MLATGETLHSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSVTYGAGGSTRAGTVKATQD
IADESTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGPWVEHPQGV
RYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVDKCRAGADYAITQMFFDPE
DYLRMRDRVVAAGCDTPVIPEVMPLTSVRQLERFPQLSNATLPAALKERILAAKDDPAAV
RSIGIDFATRFCAKLLSEGVPGLHFITLNNSTATLEIYENLGLHKQS
>A0A175VGR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas enteropelogenes|TrEMBL
MGFHSARQVEALNQSLADLNGDISVSFEFFPPNSEGMENTLWQSIERLKVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRSIARDYWNSGIRHIVALRGD
LPQGVDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLEHDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQA
>Q2G4C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199)|TrEMBL
MAKASLIHPNWDKAPDGITDGFSLEMTAKDEASLRDAAPLIPADTPIAVTFLPGEDVAAR
VAATVAVRQLGFEPMPHFSARRITSEDDFEGYLKAVVEQAGVERCFIVAGDPPEPVGPYF
DTSALIATGAFERSGIKAIGIGGHPEGHPNMTEAECWAVLEKKVAEIERRGMAPLIVTQF
GFDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTAVLKKYGISVT
NLLGTAGPDKLVDAFAKGLGPEHGKVRLHFYPFGGLTKTLEWIHGYNKKHGIGA
>A0A2E3M6L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MVSYAQGVDALNQSLSELRDIDVSFEFFPPKSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAQDYWDSGIRRIVALRGDLP
PGVKDTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIS
QFFFDTSVFLRFRDRAAAAGIDLDLVPGILPVTNYQTLVKFAGFTNVHVPGFLHKMFDGL
DDDDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRAG
>A0A2E5XDY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
MVEFVRQETGDYFHIEVACYPETHPEARSFSQDVAYFKQKVDAGADAAITQYFYNVDAYF
RFVDYCQLRGIDIPIVPGVMPITNFENLKRFSSKCGAEVPLWLGNRLEDFGDDTNGIKQF
GIDVVTELCDDLLTGGAPGIHFYSMNLAKSVRQIWNNLSLQQRDA
>A0A1C7GCT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp. YL32|TrEMBL
MKTSSLFNHKTVLSLEVFPPKRTAPVDTIYNTLDELKGITPDFISVTYGAGGSENSQTTL
KIASAIKHKYGIESVAHIPCLNLTREDVLLILEQLKEQKIENILALRGDRVPDREPAGDF
RYASDLVEFIKLHGDFNIIGACYPEGHQESGGLVRDMKHLKDKVDAGVSQLITQLFFDNE
YFYRFRERMDLVGIHVPVEAGIMPVVNKKQIERMVSLCGVNLPKKFISVMERYGDNPIAM
RDAGIAYAVDQIVDLAAGGVDGIHLYTMNNPYIANRIYESVFRLMAS
>A0A3M1ZGM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MSKFQESLLDENTFSVTWELVPGRGAREKAQEVVVESAEAAAKSGKIHALTITDNPGGNP
AISAEMLGAEINKLGIEPLVHFTCKDKNRNQLEGLLYGLERENVRNLLIMTGDYPVSGFG
GRAKPVFDLDPAQLLQLIGALNQGLEVPTFKGSTTLGPTHFFAGAAVSPFKKLESEQMGQ
YYKLKKKLESGAQFIVTQLGYDARKFHE
>A0A523QJ51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium|TrEMBL
MKVIEFYKRSKTPVFSIEVSPPLNGEPLNPVFDTINSLKEFKPAWCSVTCGALGRPRGGT
ISISGRIKRECGIESVVHFICMGRSRQDIENLLIEMKYEGIENLLVLRGDPPKGETDFRP
HPKGHRFASQLVGQIRLLNQGKYLAEEEGEYRQVLPTDFCISVAGYPEGHPECPDKKKDL
EHLKMKVDEGADCITTQLFFDADHYLRFVENARKIGIQVPIIPGVMPIANWPQLRFILNQ
QLGINIPQHLVEKLEKYHSDKDEVSAQKFGTEYIASMCESLISGGAPGIHLYTMNSPARA
RRVIQEIYPKILGLKHKKGVGGFEPTTLLLLLSEE
>A0A374JZN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. OM06-34AC|TrEMBL
MNILESLKDKLLVADGAFGTCYVGMYGEQGTVAPELANMRHPERVLEIHKEYVKAGAGLI
RTNTFAANTASLDADTDYVISNVRAAVKLAKQAAEEDVEAADCVRTSDAVVTEADESGTY
RKKVSVAGDIGPIPADAGLTLNERVSQYKLLGEAMQDMGVDIIWFETFPEFNVLEPVVKH
LKARKNTPVMVSFCVNQFGYSNCGFSARALLSQVAGNQDVDCVGFNCGVGPYHMLQLLKK
LDIDCGKPVSVMPNAGYPKFTQSRLVFNDNKEGFIDKIQDIAALGADIIGGCCGTNPEYI
HQIMERVKTGDIAKAAKVHVEKVQADSAVKDNFLKGRLERGGAATKNADGHKHKLIAVEL
APPVDVNDQKLLDAAHILKQSHVDVVTFPDSPSGRTRADSILMAEKVHKETGLRVMPHLC
CRDKNAIAIRGSVLGSQLNGIKDFLVITGDPVPVMFRQTTRSVFNFDSVGMMKLLQSMNE
EVFSGDKITYGGAINQNRLNTKFEIDRIKRKMEAGAEFFLTQPVFSREQAQILRDMKAET
GATILVGIMPLVSRRNALFMKNEMSGIEIPDEIIERYSENATRQEGEECGIQIARDILEY
TSDFADGYYFSFPFNRVHMLAHIVD
>A0A446IFH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paeniclostridium sordellii 8483|TrEMBL
MSLLKEALESGKFAVTAEMAPPKGTDLSHLIKCARAVKGRVHAVNVTDFQSAVMRTTSLT
TCKLLKDEGLEPVLQVTGRDRNRIAIQGELLSAGVFGIKNMLALTGDHTIVGDHPQAKPV
FDLDCVGILKTAQKLSQGTDMVGNQLKGAPEFYLGASVTPRYTPIEVQLLKMKKKINAGA
EFFQTQAVYDIDTMRDFRSHTKDMNTKVLAGIIPLKSPGMAKFMNANVPGIYVPEELIDR
LKSVGKENWVNEGIKIAGELIKQLKEENLCDGIHIMAIGAEENIPAILDAANI
>A0A374JWL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus sp. OM06-34AC|TrEMBL
MKIRDLITQDKATLSFEVFPPKKDTDFADVEAAALGIAAFKPDYMSVTYGAGGSTKGHTI
QLAQEIQEKYDVPTIAHLTCVCASKEGIKTALADMKNAGIENILALRGDIPKNYDGQVFA
EFSHASELVELIKETGDFCVGGACYPEVHPDSANKHEDIIGLKKKVDAGCDYLTTQMFFD
NNIFFNFMYRIREAGISVPIIPGIMPITRRVQVKNAVKLSGCNVPERFKSIVDAFGDTEA
AMRQAGIAYATDQIIDLMANGVKHIHVYSMNKPEVAAGIQKNLSEILKI
>A0A561UM79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora viridis|TrEMBL
MALGVPSTRTDHAATVRELLAAGRRSFSFEFMPPRSETAEQKLWDAIRRLEPLNPNFVCM
TYGAGGSTRGRTVNMVGRIATETTLTPVAHLTAVDHSVAELRNIIGQYADQGVRNVLAVR
GDPPGDPTGEWVTHPQGLTYAYELVELIKDIGDFCVGVAASPNMHPRSTDWDDDIRHFVA
KVRAGADYAITQMFFEVEDYLRLRDRVVAAGCDVPIIPEIMPVTNAKQLVRFPQLSGAPF
PPDLEARLTAVIDDPAALREIGMEHATAMSEQLLSEGAPGLHFITLNGSTATLQIYQNLG
LHSS
>A0A1W9HYH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium SG_bin8|TrEMBL
MSTPLSVSFEFFPPRNDDMERTLWESVERLAPLAPRFVSVTYGAGGTTRERTHATVARLV
AETALQPAAHLTCVAATRADIDAIVEEYWSAGVRHIVALRGDALAGPGATYEPHPGGYAY
THDLVEAITRRGGFEVSVSAYPERHPDSPDWDTEIALLKAKRDAGATRAITQFFFENDLY
FQYVERVRKAGIDIPIVPGILPVQNFAQVANFAKRCGSSVPEKLARRFEGLDGDQQTRAL
VAAAVCAEQVEDLRARGVSEFHFYTMNRANLVYAICHLLGLRPQHLQKAA
>A0A6B0Y2K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boseongicola sp. SB0664_bin_43|TrEMBL
MHLPGLSFEFFPPQGVQASFRLWEAVSELSPLGPEFVSVTFGAGGAQHDLTLETVKAIMI
RFDLNVAAHLTCSGATRETTLAVADSYSDAGVREIVALRGDPPSGADAFRPHHDGFEDSC
ELISALAHLNQFSIRASAYPDPHPESPAPGADVEWLKRKVDAGASSAINQFFFEAESYFR
FRDACDAARIDVPIIPGILPIEDWRRMKRFAKRCGAHVPAWLADAFEVALRDDRHDLLAI
SVCTELCSDLLDGGVEHLHFYTLNKPHLTREVVRALRAAPTADLRYVA
>F5L0S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella parvula ACS-068-V-Sch12|TrEMBL
MTLREKHQQGQFTITVELDPPKSSSAEKTFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDAPTNFYIGATGNPGAPDLEIERQKLAAKIQNGA
HFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
MEKGGKEAGTEIAIETLEQIKKMAAGVHIMPLNDIDTTLYIIDHV
>A1B4G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus denitrificans (strain Pd 1222)|TrEMBL
MTTPAISFEFFPPRNLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETLQIVQDYAAAGVHEIVALRGDAPQGQDRFTPHPDGFANSV
ELIEAIAARGDMTVRCGAYPEPHPESPDTAADVAWLKRKVDAGATSAMTQFFFDAETYFR
FRDSCLAAGIHAPIIPGILPIQSWAGTRRFAERCGTSVPQWAEDAFAAAGKEGEAQLALD
VCVKLCERLVEGGVDKLHFYTLNKPELVLKVCAALGIQPKGEFSRVA
>A0A7V8D7V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacteria bacterium|TrEMBL
MQIKDFYNKGKTVVSFEIFPPKMGAGTIESITDKLEGFSQLNPDYMSVTYGAGGTTTGIT
CDIAGKVKNYFNIESLAHVTCLSSTKDVVIDTMDRLKSNGVNNILALRGDFPTGNQSMIP
NPLHFEYAADLISFIKKHYGDTFCIGAACYPEGHIESRSLTQDLLNLKTKVDTGVDYLVS
QLFYDNEQYYRFLDSAAKAGIKVPISAGIMPVINAKQIHNIVTLCGATLPRKFIRILDKY
EDNPAALMEAGIMYALDQIIDLVTNDVEGIHLYTMNRPEVATKIVDNISHILKRG
>A0A3L7DWF7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Seongchinamella sediminis|TrEMBL
MAKPRISFEYFPPKTGAGRDKLLNETTPALNELNPAFFSVTYGAGGTTRDTTLGIVSAIG
ETGIDVAPHLSFGGDDEDTVAALLETYRERGIKRLVALRGDMPSGMGAAMQLVHANELVA
FIRERSGDHFEIEVAAYPEIHPESKSYDSDVQFLKRKLDAGANSAITQYFFNVEAYFYYL
DQCAAVGIDKPVYAGIMPITNYQNLARFSRNCGAEIPRWICQRMESYGDDLDSVRKFGLE
VVTQLCQTLIDSGAPGIHFYTMNQVEPTREIYNSLGLS
>A0A7Y6CE56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilia bacterium|TrEMBL
MASFESRLNTGLPLVADGGLGVLLAAAVPGLRTPEEANLRAPDAVTAVHVSFINAGADLI
ETNTFGANRRKLAQHFLEDEFERINSTAVKLARDAREIAGREVFIGGSIGPVGRDGGPLV
AEQARILEGRGADVFMLETFFDLDELEEAVEAVRSVSGLPIVALMSFDSDAVTMAGVSAR
QAAARLRPLAVAAFGANHGRGPAAALSALAEMSGDGAVLAALPNVGLATMAGSRISFPHA
TPEYFGDFTASARALGARLIGGCCGTTPAQIAAIRRAVDEDRPARAASPVRGPVAVAAAP
AAEEPTELARLLATGEFVVSVQLDPPLGGRVDGLVEAARTIRESGKAHVVDVNDNPRARA
RMSGLMASAVIQREAGIEVIPHLTPRDSTIAGLESQLLGAHAEGLRNVLAVTGDAPEAGD
YPGT
>A0A7L0AXH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciconia maguari|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSEGSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSIIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A9KD99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coxiella burnetii (strain Dugway 5J108-111)|TrEMBL
MDASHLSLSFELFPPKTLTGFENLKSVWRTLQDKTPDYFSVTFGAGGGNQDKTMRVVRAL
RQDFIEVAPHLTCIGLSKTAISDLLNNYRLLGIKRIVALRGDLPLEEDIAGGDFNHANEL
VAYIRKLTGDYFHIEVAAYPEFHPETRTVQEALKNFQQKIAAGANGAITQYFYNRDAYFN
FVDACRNVGIEAPIVPGIMPISDFDKLVQFSKTCATEIPRWLYKRLESYKNDKASLKAYG
VEVVTKLCEDLIAYGVPGLHFYTLNQCEPTQTIIENLQSITSFREQAVVA
>A0A4Z0BCI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas nabeulensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATATQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SQVKVPAAPHLSCVGDSKADLRGLLTQYQQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLHNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2A2QDM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium Tous-C1TDCM|TrEMBL
MSPDRPISELFAQNRPLRSLEFFPPKDDAGVEALRATAATLKRMAPDFVSVTYGAGGTTR
DRTAQVSALLKQEFGFTVMPHLTCVGHSGAELSDVADRIHGGGFRNIMTLRGDPPKGATE
FKVATDGLRNAHELVALLKSRHSDFCLGVAGYPEKHPEAPSLDVDLTHLKRKVDAGADFI
TTQLFFDNTVYYRFVERCRAAGITVPIVPGIMPVLTLKQIQRFTSMCGATLPKQLITRLE
VAAENADVTETIGIDWALTQIRGLLANGAPGYHLYILNRAKGALALTAGLAA
>A0A061BDE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodosporidium toruloides|TrEMBL
MTTTPELRSSHPSTKVVDRIAQSDPSKPFYTFEVFPPKTDAGLVNLLDRIDRMSALNPAW
MHVTWGAGGSTQERSLQLAGESQSMGLETCLHLTCTNLEEGVLDRTLKRAKELGVVNLLA
LRGDPPRGEEYWTASSDKFQHATDLIKYIRKEYGDDFCIGVAGYPEGHADSADKLADVEY
LFEKQQAGADFVVTQLFYDVGVFMEWYRACRKRGITIPIIPGIMPIQNYLSFRRMTNLCG
THIPPQILDDLQRIQHDDAAVKEYGVQLAVKMMRELFENDIRGFHLCTLNLEKSVTRVLE
LLQWVEPGSTKISARLRKGLSPNGAPLPKVINSLRPAPSTGANVAGPDIARKDSPASWDE
FPNGRFGDARSPAYGEMDGYGVSLKLPPAEAMRQWGQPTALSDVSRVFSSYLRGSLPSNP
WSEEPLRAETEMISSHLIEMNDKRHWWTVGSQPAVDGAPSADSVHGFGPKGGYVYQKAFV
EFFLTSEELDELERKSDEDERRRRESGEGDDGLIKWFAGNARGEFRCNMGKGDVNAVTWG
VFGAKEIVTTTLIEEMSFRAWCEEAFALWNEWSLLYPANSPSRTFIRSLADSRWLVSVVH
HDYKEKDALWKWLLALKRPEEAQGAAKGEAEGR
>A0A3N2H232|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis thermoflava|TrEMBL
MTSVIERLRGESPAFSIEFFPPRDAADEAVLWRSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDPYGEWV
PHPQGLSYAEELVALVRSLGDFCVGVSAFPYGHPRSLDLDTDTKYLVRKFRAGADFGIAQ
LFFEAEDFLRLRDRVAAAGCDALVIPGVMPLTTPRTLHTTIRLSGAPAPQRLLDRLEPLA
DDPKAFRAEGLDVVTELCERLIAEGVPDLHFYTFNRSKATREVVHRLGLVPARA
>A0A1Q7PAW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium 13_1_40CM_3_65_7|TrEMBL
MGVRVIGGCCGTTPEHIAAMRHALAEPVARTTDLTIPAELRSSRPAEPELAARPQTPTPL
AQKLGRTFVVSVEIDPPRGVHDRRELDGCRRLKDAGVDVVDVADNPMARLRMSPWAMCAR
IQSEVSLETVLHFTTRDRNLMRLQSDLLAVHALGVRNVLVLRGDPPQMGDYPNATAVSDV
KPSGLVRLIKKFNQGHDVAGNAIGAPTGFTVGVALNLAAPDLDREARILERKMAAGADFI
CTMPIYEPEALDRFERIMGGLPRPALIGVLPLVSHRHAEFLHNELPGFAVPTWVRERMRL
AADGRQEGIGVAHELMEAVRSRVGGVYLIPSFGRYDGVLELVRLARQPATT
>A0A1Y5RYF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseisalinus antarcticus|TrEMBL
MPAPNVSFEFFPPKSLEASFRLWHCVQTLAPLDPSFVSVTYGAGGTTRKLTHEAVGTIHK
TSGLNVAAHLTCVDASREETMAIADGYAEVGVTSIVALRGDPPKGAGRFTPHPDGFASSV
ELIEALRETGKFDIHVGAYPEKHPDAADTRADVEFLKRKIDAGATGAITQFFFEADTFFR
FRDACAAAGIDAPIRPGILPIENWNGTRKFAQACGTSIPQIIHDAFDNAVRDGTTDLLAT
ALATELCDTLLQGGVDHLHFYTLNKPELTRDVCHALGVTPKASLQNVA
>A0A261KT03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrocoleum sp. CS-953|TrEMBL
MNQFRNAVKSGEFLITAEVAPPKGTDPTHMIKMAETLKGRVHAVNITDGSRAVLRMSSLA
ASIILKKHGLEPIFQVACRDRNRIALQADLMGASALGINNILALTGDPVKAGDHKDARSV
FDMESVRLLKMIAKLNQGMDWNEKALPDGPTDLFVGAAVDPQSPSWSGLQKRFERKLLAG
SQFFQSQLISDFEKLEKFMSQIGLDSKKPILAGIFLLKSAKNAAFLNKYVPGVDIPEHII
NRLANAEKPLQEGIKIAAEQVTMASKICQGVHLMAIKREDLIPNILDMAEIAPIR
>A0A842I219|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmobacter straminiformis|TrEMBL
MTVTPRISFEFFPPQTLDASFRLWETVQMLAPLKPSFASVTYGAGGTTRKLTHEAVATIG
RNYGLNVAAHLTCVDATRAETLEIAESYAAAGVTEIVALRGDAPKGADRFTAHPEGFASS
VELVEALARTGKFKIRVGAYPEPHPDAADKTADVTWLKRKIDAGATSAITQFFFNADTFF
RFRDACAKAGIDAPVIPGILPIISWEGAKKFAARCGTQVPASLDEAFRLAARDGREELLA
LTQCTSLCARLIEGGVEDLHFYTLNRPNLTREVVRALGIAPEVALEKVA
>Q88E30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAILARAHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQVARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQASPKPMLACLMSLTHGRATMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALETRIEYWQTQVQSLEQWAPA
WHASWQMPGLPAVTFHPPQAGWRLDESRVDASFKEKARYHLMHGMHALLFSRRNSLSKAF
GWAVRQPLWGTRVGAHVLHTLERSVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A7V9VN03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MRIDQILTERRPVFSFEFFPPKDDAGVARLETALAELALDGPDFTSVTYGAGGSTRGRTV
GITKRIKEDFGIEAMAHLSCVGSSVAELRGILDQFGEAGIENVLCLRGDPPAGETEWRPH
PEGLRYSTELAALIAADYDFATGGACFPEVHPEAVDLAHDLGFLKLKLDAGVRFLITQLF
FDNELYFDFVEQARAAGIDVPIIPGIMPVTGYGQIKRFTEMCGTSIPPALERELASRASD
SEAVSELGVAYATLQCADLLARGAPGIHFYTLNRSPATRAILAALRAARPWDRIAAPV
>A0A4Q2TAH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides zhouii|TrEMBL
MRNKSTAATLTRLLENARYEVLPTATTEDKVLAHVPRERTITVTASPSKGLESTFDLTER
LAGHGYTVVPHIAARMVSGRSELEEIVERLRGKGITSVFVPGGDAEAVGDYPDALALLED
LKALGSPFSHVGITGYPESHPTIHDDLTVQSMWDKRRHATHIVSNLTFDPAVVRDWVRRL
RARGVAMPVLLGIPGPVERTKLLGMATKIGVGESTKFLAKNKGLFARLAAPGGFTGESFL
EKCAPALGEENALVEGLHVFTFNQIGETEAWRTDMIERLRD
>A0A3D2PFN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MELKELFAKGKFVVTSEVGPPKGWQIEKTLEEAEILRGKVDAINVTDNQSSVMRFGALAT
CHFLKDRGFEPVFQITCRDRNRLALQSDILNAAAFGIENLLLLTGDHPLLGDHKDAKPVF
DLDSVSLIHTVKKLEDGSDLAGNKLEGEPPKFCLGAVVSPCAEPLEPQLFKMEKKIKAGA
EFFQTQAVYEVDKF
>A0A5B0AHI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. ANT_H56B|TrEMBL
MTKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALCA
RGETDIAPHMSCIGDDKAEIAELLEHYKSLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFELDVDNLVNKYQAGANASITQFFYNADSYLYLR
ESLEKRGIDTVAQPLVAGIMPITNSSNLMRFADSCGADIPRYVRKQLADFGDDSKAIREF
GFEVVYRLCERLISEGVPAMHFYSMNKVEPNKRLIEALGLIA
>A0A5C6AWF0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula pilleata|TrEMBL
MTLSDQYRTEGCAVSFELFPPKTEEGIEALCLNVERLLQFKPQYFTCTYGAGGSSQRATL
EVLKRVKEITNLPVASHLTCVGSTVEQLCEYLTQATEIGVDYIVALRGDPPKGTEEFCVT
EGGLRYANELVELIRSNFPQLGIAVAGYPEVHQEAPDATTDLDNLKRKVDAGADIIITQL
FYDNADFYRFRDQCEAAGIRVPLVPGILPVTNFKQAQRIAGMCKAAIPASLEVEMTRDDS
PEHQFRVGVDHARQQTTDLMKNGVPGIHYYVLNRSEAAAELLDGLQTAGSAS
>A0A536W8G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MRGVLHSRLRRDPRMDLATKEQSSSSVISELQRHLQNGSFVVTAELSPPVSTDPAEFIDH
ALALRGLATAINVTDGAGSRAHMSSLAAAHFLVRSGVEPVLQITCRDRNRLALQAELLGA
AALGIRNILALRGDDPKLGDQPDTKPVFDLDTTALLATAQQMRSEHRLPSGTEIKGAVKF
VLGAAELPVDPPAGWRPNGLVSKMEAGAEFIQTQFCMDPDAVRRYAARLLELGVAQKLPI
LIGIAPIPSARSARWMKEKLFGAMIPDRLVERLERAADPKAEGRRICVELLQQLVETPGV
AGAHVMAPAFHSAIGPVIEASRVAGAKRAGARRG
>A0A653TYE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citricoccus sp. K5|TrEMBL
MSSPNPTPTASGRPSVITDPSLEMTGKDKDIDALREAAPLIPAGTRINVTFLGNEDLGMR
VKASSAAKELGYVPVPHISARRLTSEAELVEFLTALRDQVGATHAFAVGGDPSEPMGPYG
ASVDLITSGLLKEYGFTDISIAGYPEGHPDISDAQLWDALESKYASLQEQGLNGTILTQF
GFDVDPVFAWIKEVRRRGIDLPIRIGVPGPAGIKRLLTYASRFGVATSAGIAKKYGFSIT
NLLGTAGPDKMIGDLDAGLTPAEGDVKLHFYTFGGTKTTAEWIKDYQAKH
>A0A5D4FYD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium urealyticum|TrEMBL
MSTMIFFMSASNPHGHHEKTSPLPGTPPQPTLQVPVSEAIRGYSPGKIPFSVEFMPPRDD
AAQTRLWNAAEAFHDLGVSFASITYGAGGSTRERTMEVAQQLAAKPLTTLMHLTLVDHSA
DELRVMLQDYARRGMTNVLALRGDPPGDPLGTWQPTPGGLNYASDLIELIRNTPECENFD
IGIASFPEGHYRAEDLEQDTQVTLHKLRLGADYSITQMFFDVENYLRLRDRLAAADPIHG
AKPVIPGLMPITSIRSVRRQMELAGGEVPVKILERLEKAAAGDEVANRDAVREVGIDITT
EMSERLIAEGAPNLHFMTMNNVRATQDVLHNLGMAPAWGPGYGQDMVR
>A0A1G1L202|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica bacterium RIFCSPLOWO2_12_FULL_44_17|TrEMBL
MKISDYYKKNKYTFSFEFFPPKNDTGEKKLFEAVRELKILSPSFISVTYGAMGTTRNNTI
GLVKRIKSDIGIESAAHLSCIAHTKQEIEAILAELVSDGIENIVALRGDIPQDQPDFKSP
ENGFRYAADLVRYIRQHPKYGNQFTIAVAGHPECHIECTDKEKDLEHLRMKVAEGADIVI
TQLFFSNHDYFDFVSRCRAVGISLPIVPGIMPITNGAQIQKFTRVCGAKLPAKIQNAIFR
YGDDQASIEAFGTDYAITQCEELLRKGAPGLHFYTLNKSTATRKIFRSLNLSGV
>A0A522VW36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MLTSLEGGTRTAALEIAAYAAELLACGSIEMGAHQPEMARRIAALLPSGTPVFVNHLPRH
SLADALASLVAVRETGLEPVPHLAARRIASREELEAFLQRAVGAAGVRKVLLIGGDEIAP
LGPYADGAAALRSGILSACGIREIGIAGYPEGHPRIPAAALESSFTEKLALAASEGLGAF
VVTQFSFAPARVIEYCAGLARRAPGVPVYVGLAGPNSTAALLRFAQRCGVSASLRALRAQ
GFGAVQLVTHTDPGDQLTTIARYCMAHADCNVVGAHVFSFGAAVAGAEWMNRFIARST
>A0A2A6CWW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pristionchus pacificus|TrEMBL
MTQIEIDCVARNASSASLSPYCGQPSPALANGGASSGDLKKCRLSETALSRPLSRTGSDS
DEFLKFEVPSQVGAQCSYRPLHERIEKRVKAGTPFFSLEFFPPKTANGVANFYTRLDRYK
EGDPLFVDITWHYGGDPANLTRETSSSSIAAGCLDYCRMDTMLHMTCTQYTKEQTIAHLE
QSKRIGLRNILALRGDLPPNTSSDAPVIKPKYMALDMIKWIKEEFGDYFTIACSGYPLGH
PEAVSYAEDLKYLKAKVDAGAQLIVTQLFFEAEAYERFVRDCREMGITVPILPGIMPIQS
YDSIRRIAQLSQLAIPDSILADLEPIKHDDDAVRNYGRHRAIEMCRRILSNGTAPAIHMY
TMNREGSCREILQELGLWHKRPMRALPWEPHGVNHPLRCKEDVRPIFWSARPKSYIYRTR
DWDDFPNGRWGNSSSPAFNDLHDYYLFNLHSTVNEKDKLRDMFGHELRSIDDVGRVFARY
IDQQDNEHGVKVTTLPWNEQENGVQAETSLISDDLVWCNERGVLTLNSQPSVNGAPSTDP
LVGWGKPGGYCYQKAYLECFISAENAASLLEFIDEHHPRINYHIVNKDGSMDRSNAEATT
PIAVTWGVFPGAEIAQPTVVDPISFRVWRDEAYDMWMKNWAYLYPADSRSHQVIEEIHNS
FCLLTLVDNDFVHPSILFDVVREMVARTETRTASSSPKEAVAQAIKA
>A0A2U1WZT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum sp. TSH20|TrEMBL
MTAPTSALPSISFEFFPPKSEKMEQSLWQSIRRLAPLSPSFVSVTYGAGGSTRERTHATV
CRIQAETGIPAAAHFTCVGATRDEIDAIARTYWDAGIRHLVALRGDPPETAGGVGGRYEP
FPGGYAYAADLVAGMKRIADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQF
FFDNDAYFRFLDRCAAAGIHVPIVPGILPITNFARAVEFAGKCGASMPKKLAETFEGLDD
DPETRQLVAATVAAEQCQALQAQGVNDFHFYTLNRSDLTIAICRMLGVKAKAVPAAAAVA
G
>A0A537B9W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MRGVLHSQLRRDPRMDLATKEHSSSSAISELQKHLRDGSFVITAELSPPVSTDPAEFIDH
ALALRGLVTAINVTDGAGSRAHMSSLAAAHFLVRSGVEPVLQITCRDRNRIALQAELLGA
AALGIRNILALRGDDPTLGDQPDTKPVFDLDTTALLATAQRMRSEHRLPSGTEIKGAVRF
VLGAAELPVDPADGWRPNGLLSKMEAGAEFIQTQFCMDPDAVRRYAARLLELGVAQKLPI
LIGIAPIPSARSARWMKEKLFGAMIPDRIVDRLERAADPKAEGRRICVELLQQLAETPGV
AGAHVMAPAFHSAIGPVIEASRVAGTKRAGARRG
>A0A537B5W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MQSQKKLPRTFSFEFFPPKTPEGMEKLRASWKQLAQLKPRFFSCTYGAGGSTRDRTLETV
LEIQAAGHRAAPHISCIGATRADVAATLELYKSKGIAHIVALRGDLPSGAASAGELRYAS
ELVAFIRERTGDHFHVEVACYPEFHPQARSPHEDLRNFKRKVDAGADAAITQYFYNIDSY
LRFIDDCEGLGIDLPIVPGIMPIGNFAQLARFSDACGAEIPRWLRMKMQSLGDDVASIRS
LGLEVVTDLCDRLLSAGAPGLHFYTMNQAGLTSTIWQRLGL
>A0A7K6L481|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Falcunculus frontatus|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKENSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A6B0CD42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGVDVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPKKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLSKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKISKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A093JA87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fulmarus glacialis|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDHMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPDAESYEADLRHLKEKVCAGADFIITQLFFRDCKAIG
ITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCR
ELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRVEDVRPIFW
ASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTG
EESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPN
INGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQN
ITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRM
IIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A1Q5RVL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. NAS96.2|TrEMBL
MTETISSVPNGQRAPKAPKISFEFFPPKTEEMERNLWETINRLAPLAPNFVSVTYGAGGS
TRERTHSTITRILRETDLLPAAHLTCVSASRSEIDDIVDRYHEVGVRHIVALRGDPPGGI
GTPYFTHPDGYQSSAELVAGIKRRHADIEISVSAYPEKHPEAADFDTDIDTLKAKVDAGA
TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE
KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA
QKAA
>A0A418MB69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrisoma montanum|TrEMBL
MTKITDHIRNANGKPIFSIEVIPPVKGDTLKNLLDNIEPLMAFKPPFIDVTYHREEYIER
PLPDGTIQKIVTRKRPGTVGICSAIMHKFGVDPVPHVLCGGFTREETEDFLVDLHYLGID
NVLVLRGDPAKPFNTFKPKDNGYSYASELVEQVANMNNGVYLHEEDTALSPSDFCIGVAG
YPEKHFEAVDHEIDFQYLKQKIDKGADYIVTQMFFDNQKYFDFVGKCRQAGITVPIIPGL
KPLSTRKQLQVLPRIFHLQMPPDLVTAVEACENDQQARQVGIEWCIQQCRELIAAGAPVL
HFYTMGKADNIAKIAKEVF
>A0A3R5WMI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus eutactus|TrEMBL
MKIRDLITQDKATLSFEVFPPKKDTDFADVEAAALGIAALKPGYMSVTYGAGGSTKGHTI
QLAREIQEKYDVPTIAHLTCVCASRDGIKNALVEMKNAGIENILALRGDIPKNYDGQVFT
EFSHASELVELIKESGDFCVGGACYPEVHPDSANKHDDIAGLKKKVDAGCDYLTTQMFFD
NNIFFNFMYRVREAGINVPIIPGIMPITKRVQVGNAVKLSGCNVPERFKSIVDAFGDTEA
AMRQAGIAYATDQIIDLMANGVKHIHVYSMNKPEVAAGIQKNLSEILIV
>A0A2G6UBF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. 52|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYLD
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTPGGHASAMDLVHQINDLGRGKYLHNDEKACDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKEKVDAGADYIVTQMFFDNKRFIEFVKKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEELINEVEKAKNNEAVKQIGVEWAIAQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A1Q5N155|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02488|TrEMBL
MAFGTPSTRTDRARTVREMLATGKTLHSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSV
TYGAGGSTRAGTVKATQDIAAESTLTPVAHLTAVNHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGPWVEHPQGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRMRDRVVAAGCGTPVIPEVMPLTSVRQLERFAQLSNATL
PTALKERILAAKDDPAAVRSIGIDFATRFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A4S2DL95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sartagoforme|TrEMBL
MNINNLFNEKKVVFSFEIFPPKQESNIETIYNTLEELKDLKPDFISVTYGAGGSLTKNMT
CEISSIVKNKYGIEPLAHLTCINSTKDNVDKILDDLKNQGIENVLALRGDIPADYKGEGS
FRYATDLITHIKGRDDFNIVAACYPEIHPDSKSIEDDLLNLKRKQEAGATHLVSQLFFDN
NYFYNFLDKKEKYNINIPVEAGIMPVINARQIKRIVSLCGAKVPQKFLKIMNKYEFNPEA
LRDAGIAYANEQIIDLISSGVDGIHLYTMNNPYVARRISEGVSSIINTINTCENVANK
>A0A149UR84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter cerevisiae|TrEMBL
MSLSRLSVELIPRSEDALAQDVTSVKTLFPAADTLNIPDLMRFPLRSWDAAALTMPQFGT
VVPHVRAIDIAPGAPLPGSTLPGLKEVLVVHGDPPADLAHRTYPNSTESIIRRYRKEAPH
LRIYAAFDPYRRAPWRELEDIARKKDAGAEGFFTQPVFDLKLFDLCREWLQDEQVFWGLS
PVIGPRSRSYWETTNHVVFPRDFEPTLDANIQFAQSVLRQLSQDQGCAYLMPLRVKLDQY
LPPLMDALTA
>A0A2P8NDH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor sp. StC3|TrEMBL
MNQFRLSRRPDIGDQIDVSFEFFPPKNDAMEARLWETTERLQPLSPSFVSVTYGAGGSTR
ERTARTVERIIRETALTPAAHLTCVDATREEADQVIRQFLDLGVSRFVALRGDPAEGVGA
RYTPHPGGYANAAELVEALARHGAKDISVAAYPEKHPESPDFATDIDMLKRKVDNGAKRA
ITQFFFDNDLYERYVERARRAGIYVPIVPGILPVHNFGQVANFAGRCGAHVPAWLAERFE
GLEKDPQTHALVAAAVAAEQVLDLVERGVSDFHFYTMNRADLAFAICHMIGIRANGASED
AKPAAA
>A0A1V5KZE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium ADurb.Bin444|TrEMBL
MNRFKAACMSGDFVVTAEIGPPKGTDISAMVADIELLKDRVAALNVTDNQSAVMRMGPLS
AAHQVIERGGEAIYQLTCRDRNRLALQSDLLSAHVLGVRNLLCLTGDHPCIGDHPQAKPV
YDFDSVHLIQCAQGLNEGFDWNGAGLEGATDFFIGAVVAPDADPIRPQLFKLAKKVEAGA
EFFQTQAVYDMQRFADFMTAARKMTAGTRVTVLAGMLLLAGAGMARYLNASVPGIVVPEA
LVRELEEAPKGEAALVGAAICARHIRFLRDEGICDGVHIMALGRVDLVPRILDMAGEL
>A0A7Z2BVF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. SO10|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRSIARDYWDSGIRHIVALRGD
LPPGSGKPEMYGSDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMSAMFE
GLENDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAMGG
>D4M5K9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ruminococcus] torques L2-14|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPE
AMKQAGIAYATDQIIDLLANGVNNIHIYSMNKPEIAIAIMNNLSEIIKC
>A0A3Q7XDJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ursus arctos horribilis|TrEMBL
MVNEPRGDGGPPPRSEGSSSGSESSKESSRCSTPGLDPERHDRLREKMRRRMDSGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSREQITGYLQKARRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRH
IRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFQFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQQLLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFAHYLSGEPNQQGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLENCLWQVVEDTFELLNQPAPEGETEAL
>A0A7T5EI45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus composti|TrEMBL
MSRKKRELRAYLQENLLVGDGAMATQLYRMGVPVGVSFEELCLSSPQLVHDVHKAYYEAG
ARLLETNTFSANRDALSRYGLEHKVTRINRAAVAIAREAAQEDAFVVGSVGSILAGRVRQ
KVLDEFRDQYEEQAIALLHAGVDGLILETFLDVEELLLAINVIRPLTDLPLICQLATLEV
GRTRDGYTLTEAFAQLQQAGADIIGLNCRLGPAEILRSFEQAQVPEGALLSAFPNAGRLG
LADGEYAYKSSPEYFAESALRLREQGVRLIGGCCGTTPEHVKAMADALRGLAPQPRINPV
IADPERTSPSAHYVRDPQKPSIVERVKTGTTIIVEFDPPKDLDTEGFIQGCCELHAAGAD
SITLADNSLANVRMSNMALGAIMKGQYGMDPLIHIACRDRNLIGQQSHLMGLHALGIDQV
LVVTGDPSRFGDLPGASSVFDVTSFDLIRMVKQLNEGISFSGRPLKQKAQFIVGAAFNPN
VRQIDAAIKRLEKKVEAGADFIMTQPVYDVESIRLVHESTKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSQEALERMRRVQGEAARQEGIKIAKELLDAAIPAFNGIYLITPFNYYQ
MSVELIQYVQQKSSLLQTSGQI
>R4KE84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfoscipio gibsoniae DSM 7213|TrEMBL
MKNLSKLQQILDSGQFAVTAEIGPPKHSSAEGIRHHAEMMRDYVDATNITDNQTAIVRLS
SIAAGVHVLANGIEPIVQMTCRDRNRIAMQSDLMGAYSLGMRNVLCLSGDHQKFGNHPTA
KNVYDIDSMQLIYYLRRMRDEKLFFSGEEIKEHEPQFFIGAVANPFADPFEFRVDRLEKK
VEAGAQFIQTQCIFDMERFERFMEMVRERGIDERVHILAGVTPMKSWRAAKYIQNNVSGM
IVPDELVERLKNAEDPKREGVDICIEQIKYIKEKVKGVHGVHVMAIAWEEVVPEIVEKSG
LYPRPKVG
>A0A3Q7Y4G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ursus arctos horribilis|TrEMBL
MDHPTPKVLPARPRGPSLGMWALEAGRVRFSVPPSISRNRAMVNEPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERHDRLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSREQITG
YLQKARRLGLKNILALRGGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFF
QFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNY
GIEQAVSLCQQLLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKR
REEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREEL
LKMWGEELTSEESVFEVFAHYLSGEPNQQGYKVTCLPWNDEPLAAETSLMKEELLRVNRQ
GILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVN
YHIVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPVSFMFWKDEAFALWIEQWGK
LYEEESPSRMIIQYIHDNYFLVNLVDNEFPLENCLWQVVEDTFELLNQPAPEGETEAL
>A0A7Y4N1A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus coralloides|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTVEELAPLEPGFVSVTYGAGGSTRDRTV
DLVTHIKRQTGIEAMAHLTCVGHTRDELRDVLRRLDAAGIENVLLLRGDPPQGQTTFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVGALKGRS
>A0A2V6BIU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRGNSPTFSFEFFPPKTPEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQRTTKLDPIPHLTCVCHNEQEVEEILLRYAKSAIGNILALGGDRPAGIAYDKSR
DSFQHAIDLVKFIRRF
>A0A2V6FE58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHFIRDIYATARTAKRPVISFEFFPTKTEEGERALLEKTIPALMQLKPDFCSVTYGAGGS
TRDKTLTIVDRIQRQHGLAAMAHLTCVNATKEEISAYLTEARSRGIKNILALRGDPPGGT
GEFKKTEGGFEFSYQLVEFIRQAGGFSIGVAGFPEGHIACQEGKLVDWQRLKNKIDHGAD
FVITQLFFSNRDYFEFRDFLTSLGVSVPLVPGIIPILSTAQIKKFTALCGAKLPAPLVAE
LEKRGDNDEAAAQYGIEYATRQCEELLRDGAPGIHFYTLNKTRSATVILKNLRLT
>A0A3S1U9L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.003.01.2.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A177EQX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fonsecaea monophora|TrEMBL
MHVSKKLELAHQQKKPTFSFEFFPPKTAQGVQNLYDRMDRMHNLGPTFIDITWGAGGRHS
QLTSEMVNATQNYYGLETCMHLTCTDMERHQVDEALRRAYKTGCTNILALRGDPPRDQEK
WEAKDGGFRYAKDLVKYIKARYGDHFDIGVAGYPEGCDDQRDVDLLIDHLKEKVDAGASF
VITQMFYDVDIFLNWVKKCRDRGITVPILPGIMPVQTYAAFVRRANWTKCHVPPEWFEAL
EPVKNDDAAVRAIGKDLVADMCRKILEFGIQHLHFYTMNLAQATRMVLEDLSLTPETSGT
RLEKPLPWRQSLGFNRRDETVRPIFWRNRNASYISRTADWDEFPNGRWGDSRSPAFGELD
AYGVGLKGTNEANIKLWGKPRSLRDVTSLFVRFLQGDLERLPWSEGAISSEADIIKDDLL
QLNTRGFLTINSQPAVDGASSTHPIYGWGPAGGWVYQKAYLELLVFPSMFKTVMDRLNAD
KNLTYYAVNRKGELYTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WAKCYPAGSGSRKLIEKIIDECYLVNIVNNDFHQNKEIFKVFEGLETKDLDLVIEDTVPS
SVENGTKDVPNGDASLGDVEKGLANGEQPKAPSKAGADVLSN
>A0A3P4ASE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus thermophilus|TrEMBL
MKIRDLLKARRGPLFSFEFFPPKDPEGEEALFRTLEELKAFRPAFVSITYGAMGSTRERS
VAWAQRIQGLGLNPLAHLTVAGQSRKEVAEVLHRFVESGVENLLALRGDPPRGERVFRPH
PEGFRYAAELVALIRERYGDRVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIEIPILPGIMPVTSYAQLRRFTEVCGASIPGPLLAKLEQHQ
DDPKAVLEIGVEHAVRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGLRSASGQP
>A0A0R1UVK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus satsumensis DSM 16230 = JCM 12392|TrEMBL
MKLTELFNSKTVFSLEVFPPRNELSSQRIIPTLEGLQEIAPDFISVTLGAGGIGHDQGTF
EIADFIQNTLNIPAVVHVPCLYLSQEQVLTLLDQLKEINVTNILALRGDFIPGRKPVGDF
SHANELIEFVKKERPLFSIASACYPDKHREAVSFVEDIACLRKKIDAGSDHLITQLFFNN
ESFYTFKEKAEIAGINVPIEAGIMPCTNKKQIERIAKVSGVPIPHKYSQMLDKYQNNKEA
LEDAGVAYAVEQIIDLVAHGVDGIHLYTMNHATVAQKIWRETRSIFKATSKNS
>A0A2N9NXH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MFARCMHLVRDIYAAKAAAGQPVVSFEFFPPKTPEGEHALLEKTLPALLETRPDYCSVTY
GAGGSTRDKTLLIVDRIQRHHGLTAVAHLTCVNSTRAQIADLLEQIRALGVKNILALRGD
PPGGGEFQVTPGGFEFSSQLVQFIRTQPGFCVGVAGFPEGHIACKEGKHTDWRHLQEKVQ
AGADFVLTQLFFDNADFYEFRDHLTRKLGVTVPIVPGIVSILSAAQIQRFTALCGARIPP
SLAERLGELGADDHAVGQFGIDYATRQCEDLLRSGVPGIHFYTLNKSLATVQILKNLGLA
>A0A2V6JGJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
LRALQPCQNDSDMVRRVGIQYALEQCHDLLANDVAGIHFYTLNQSGATRMIFDSLGIPRH
RNLQASSV
>H1LP03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus sp. oral taxon 851 str. F0397|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIESYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPE
>A0A6N7LAS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium terangae|TrEMBL
MTTRTLYPAERGNLRLSFEYFPPKTDEMEVQLFQTVADLSVFDPAFVTVTYGAGGSTKAR
SLTTVKRMIGEMGIGNTAAHLTCVGAPKAEVDAVIEEFLAFGVRRFVALRGDPQGGIGSA
YQPFPGGYENAAALVKALRARGDFEISVSAYPEKHPESPDVAADIDMLKRKVDNGATRAI
TQFFFDNDDFELYLERVRRAGVQVPIVPGILPINNLAQVQRFAGLCGARVPEVIHSRLAH
LEDQPAERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLVTAVCDLVGYARVPAREAA
VDLPMRAVASA
>A0A836JDN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acromyrmex insinuator|TrEMBL
MRNLILENDMCERNDADGNDNPSTPDFHIENPRKTVVDLRQLLKDKISKNEIFCSFEIVS
TRKSGAFYRRLLIGMEEYAPLFYALTWHNKATSDNDGYLPLDLVENFPANTLLHLAAKSL
KRDEVIYILKKAIAFGIINIFALRGDSLSENGDFEHAADLVVFIRQQFGNTFCVCVAGYP
QMHPESPSKKLDLYYLKAKVEAGADFIITQICFDSRVLINFVRDCREIGIQIPILPGILT
PTNHACLEKMIDICRLDVPIKIKEDLTRMKDDDQAVRKYSVDLIVQIITDVIRNGATYGF
HLFTLNRLSLVAEICKRIESFKAENL
>A0A2C6XWV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas rhizosphaerae|TrEMBL
MGSLAKPAPTLQRWLSGERIGPLPVRAAGQPPPLLSFEFFPPRTEALEQQLWTCIRRLAP
LAPRFVSVTYGAGGSTHARTHATVARLARETALVPAAHLTCVGATREEVDEVARGYWAAG
VRHIVALRGDPPAGTGYEPHPGGYRHASDLVAGLRRIADFEISVAAYPEVHPAARSAEDD
LDNLKRKLDAGATRAITQ
>A0A4R7B3K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paludibacterium purpuratum|TrEMBL
MAERTSNFSFEFFPPKTPEGMTRLKNTLRQLAPLKPEFFSVTFGAGGSTREGTLATVQEI
RSHGLAVAPHLSCIGSTRANIRAMLDEYRAHGVRHIVALRGDMPSGMVEAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLNNFVRKMGAGADSAITQYFFNADSYFRF
VDEIRARGVTAPIVPGIMPIANFSQMCRFSDACGTEVPRWLRLRMQAYGDDVASVRALGL
DVVTELCDRLLQAGAPGLHFYTLNQAGTVSTIWQRLGL
>A0A202DLB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium E08(2017)|TrEMBL
MHYVDILRVGITPVKSHKALQYMNKFVAGITVPEELIKRMEGAEDSKEEGVKICVEQIEE
IKSMEGVSGLHLMPIGWESITETILDKAGLLPRPE
>Q8PCI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAAKLKAYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAIDADSDLKYFKAKVDAGADAAITQYFYNADAYFHFRDA
AQRLGVEVPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AGLCERLIAGGVPALHFYTLNLAKPTTQVLQLLGR
>A0A2S7JPL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. TS-CS-82|TrEMBL
MIVNNSLSIEFFPPKTPEGADKLRTVRQALYPLKPQFCSVTYGAGGSTQAGTLLTLKEIL
SEGMAAASHFSCIGATRDSVRQQLAEFKAMGVKRLVALRGDLPSGYGAGGEFQYASDLVA
FIRAETGDDFGIEVAAYPEIHPQAKSAETDLQAFATKVKAGADSAITQYFYNSDAYFRFV
DDVQKLGVEIPIVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGYGDDMASIKAFGLE
VVTDLCDQLRSAGAPGLHFYSMNQSAATLSICENLGLIA
>A0A373MR21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AF34-12|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKERVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A1T1NRE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis pv. melhusii|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
AALCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A4Z0IX11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. S111|TrEMBL
MSQETLRTLLSTARYEILPTAGIVERVGEYVAPGREITVTASTGLTLEATLSTAEQLQAL
GFRAVPHIAARMIQGRSELTEIVDRLAEAGVDRIFVPAGDATPPAGGYVGAHDLLVDLSS
MAAPFQHIGVSAYPESHPVIADDVTIQAMWDKRDYATHLVSNLCFDPAVVASWVARVRAR
GIELPLMLGIAGKVELTKLARVATKIGVGESTRFLRKNTATFTRMAKPGGYNPRKFLDKL
APVLDDPAMGVAGLHIYTFNQIKDTEIWRRKQLAPLGGAEEFTSLQ
>A0A4Z0J2E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. S111|TrEMBL
MPSTHLTPRISASAPDSVADGLPPARGRLRRALSFEVIPPRSAAQAARMPQLLRFLDSLH
PDYLAVTSSANSDWLQGTADFISEVTDTTSLRPLAHLACTAGTEVELLTWIEHLLSAGVR
GFLAIRGDIPVGQTSLPAGHLPHADDLVGLLRRIESENVACLAAGRLGIGVAAYPSGHPE
SAGPDEDLDVLAAKQRNGADFAITQLFFDPTAYSRLRRRAEHAGITLPITDARRLHTMSR
LSGLPIPDGLLARFDGISDPASARRIGLEITAEHTAALLDQDADGLHFYTFNDQNTTEDV
LTALDEKGISVTSLLPPPPPRRWPPTQPTATTTDKDTRS
>A0A5M8ZEK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter sp. DmW_136|TrEMBL
MTGILSTWLSEKRIDRLLSCNSETPILSFEFVLPRTDAMEQRLWHCIWRLAPLAPRFVSI
TYGAGGTTQAGTLSTVLRLKRNTDLIPAAHLTCVGAPREAVDDLARCYRDAGVHHIVALR
GDPSAGAVDDSPRPGGYTYASDLVAGLRRIADFDISVAAYPETHPTALSPEADLDNLKRK
LDAGATRAITQYFFDSEIYLLFLDRCLAAGITAPIIPGIMPVSNYEQIVRFSAVCGVTVP
AWLRHLFDGTAKNPELRRIVASMVAVEQIRTLQTYGINEFHVSTLNRADLTYAIAHILGV
RPMQTNVSHNVTGLLEKTEVPDERETPADFDPTAWAQEGAPPFMLRTLFG
>A0A1N7R4B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp. MFA1 R4|TrEMBL
MSLIHPSTYHSPGNITDAYSLEVSARDISALAATASRIPPGSTISIPYLPGQDNDARLAA
ARAVRALGLEPMPHLSARRIASLAELDSFVGRAVAEAGVERCFVIAGDPPTPLGPFPDST
SLIETGVFERAGIQVVGVGGHPEGHPVMSATDRWNVLERKCHGIGMRGMTPLVVTQFGFD
ADIVLTWLKTLRERGIEHPVRVGVPGPTGIAVLARYAALCGVSACASMWSKYGISLGKLF
GTAGPDVFVDRLAAGLTQAHGNVSLHFFPFGGIAQSVKWIEQYRSRPEKLRPVSAALL
>A0A7H8ZWB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB04723|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PEALKERILAAKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A6N6ZLB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSPDTGPIGNPLSSTGSATATEFPARAPQRLAVSFEFSPPRTDAAEQILWETVKRLTPLH
PAFFSVTYGAGGSTRQRTHDTVARLKSETGIDAAAHLTCVAATQGEIDDIARAYWDAGIR
HIVALRGDPPGGMGGQYTPHPGGYANAAALVTGLKKIGNFQISVAGYPEKHPASADEKAD
LENLKAKVDAGADRCITQFFFEADDFLRFRDRAAAAGINVPIVPGIMPVSNFQAVNRIAG
LCGSKVPPWFSSMFDGLDDDLETRRMIAATVAGDLCRRLRDEGVEQFHFYTLNRADLTFA
ICHLLGVRPQ
>S4Y8U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sorangium cellulosum So0157-2|TrEMBL
MSRTRPEAPFLDAIRRSILVFDGAMGSLLYERGVFVTQNFEQLNVARPDLVKRVHADYVA
AGANVIETNTFGANRFRLERYGLVNEVRNFNLAGARIAREIAGGDAYVAGSIGPTGLVPG
VAKRDDLAAAAATFAEQAGALAEGGADLLVLETFRHLDEIKLAIEAARQAAPGLPVLASM
TFDTSGVVADGSEPERVARTLRDWGVDLLGVNCGDGPQLSLAMAERMATAGLPLCVQPNA
GLPRTVDGRLLYMATPEYFDVFARRMIQAGAAMIGGCCGTTPEHVKWMAKSARMLRGGAV
PEVTSRPHVTMDAPTGSEPTPLGERSPLAAKIAAGKFVVSVEVNPAPGLSPESALSAAKM
LIDNGVDVVNVADGPRATARMTNLAFCSLLVQRYGIEPILHVCGRDRNLIGQMAHLLGAH
AIGIKNLVIITGDPPKVGDYPEATAVYDLDSIGLLHMASTMNRGLDPAGKPIPGGKTSFL
LATGLEPGAPDLDKELARLERKRAAGADIIMTQPIFHQDLLEKVLRRIEHLGMPVLVGVL
PLVSYKNAEFLHNEVPGMQIPEEIRERMRKVPAGPEARKEGVKIAREMLFSVRDRVQGAY
LMPPLGKYELALEVLDGLKTS
>A0A6A0I0L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division KSB1 bacterium|TrEMBL
MTEKSAVKARDFANDLVACPAVDWISITDNAGGNPKLAPHALGKPILYAGKEVVIHMTCK
DLNRNGLESEAWVLSSEGFHNILAMTGDYPVAGGGGMAKPVFDLDSISLIAMLNKMNHGF
EYRKNGAQNNTERLGETQFLIGAVTSNFKMREGEVVPQYLKLQKKIECGAQFIINQVGFD
SRKIHELRIYMDQHAMKHVPLIGNVYVLNPRVAQIFHDRKIPGIVVTPPLLALCLKQRQS
ADEGRAFFYEFAAKQIAIYRGLGYRGAYLGGIYDFAAIERILEIERSFSRDDWKQFAREI
RYSRPGEFFYYLENSETGLADSSVRSPASEKKKSKHVGLVYHLSKMTHELMFASDGAFAK
LGRRLCQHAHDPSQGPGWMRLTERWSKMVLFDCRDCGDCSLPEIAYLCPESQCAKNQRNG
PCGGTKDGLCEVDGFGDCIWLRAYERLKHDAKELELLRHVPVLQDQALRGTSSWANNWLG
RDHAAKTVDQICTSEVKKRNAEEHELQLTP
>A0A2E2MRR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MPKPPTDNLRQVAAFGRAAVAGGSVAAPLPDDVEVSFEFFPPSSDGAEANLWNSIQRLAP
LNPKYVSVTYGAGGSTRERTHATVKRLLDETNLLPAAHLTCVDATTQEIDAVAQDYWDMG
VRHIVALRGDPQDSSGRYTPHSGGYSFACDLVAGLRQIGDFNISVGAYPEVHPEARSAKA
DMDNLKRKIDAGADQAITQYFFDTDVYLRFVDQARAAGIWVPIIPGIMPIHNFTKVANFS
KRCGATIPRWLGDLFDGLENDPETHKLVAASLVAEQCRTLHAFGDKQFHFYTLNQADLTY
AICHMLGVRPKHPVGSDADDRTNKKQTG
>A0A8C4ZYU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gadus morhua|TrEMBL
MVNQVQRVDGSWQTSKSDSSGASNSGESSKESSRCSTPLLDADRSDRLREKMRKRMESGD
PWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSNKETSSMMIASTAV
NYCGLESVLHLTCSNQSQETITGYLTKAKQLGLKNIMALRGDPLGTDWEDEEEGFNYATD
LVKHIRSEFDDYFDICVAGYPTGHPEAQSYAEDLQHLKEKVDAGADFIITQLFFRADTFL
KFLRDCRAIGITVPILPGVFPIQGYQSLRQLVKLSKLEVPEEIMEVIEPIKDNDAAIRSY
GIHQAVEMCRVLLDSGAVPGLHFYTLNREVATTEVLRQLGLWIEDPRRPLPWATSANPKR
KVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LKMWGEELTSETSVFEVFTSYITAQVNRGGHKVMCLPWNDDALATETNLLKDELEKVNRR
GVLTINSQPNINGKPSSDPIAGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVQGHNMTNAQDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDSCLWQVLDDMFELLDAFTDGLMS
>A0A8C5FSN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gadus morhua|TrEMBL
MLPKPQGLDSSGASNSGESSKESSRCSTPLLDADRSDRLREKMRKRMESGDPWFSLEFFP
PRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSNKETSSMMIASTAVNYCGLESVL
HLTCSNQSQETITGYLTKAKQLGLKNIMALRGDPLGTDWEDEEEGFNYATDLVKHIRSEF
DDYFDICVAGYPTGHPEAQSYAEDLQHLKEKVDAGADFIITQLFFRADTFLKFLRDCRAI
GITVPILPGVFPIQGYQSLRQLVKLSKLEVPEEIMEVIEPIKDNDAAIRSYGIHQAVEMC
RVLLDSGAVPGLHFYTLNREVATTEVLRQLGLWIEDPRRPLPWATSANPKRKVEDVRPIF
WASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEELT
SETSVFEVFTSYITAQVNRGGHKVMCLPWNDDALATETNLLKDELEKVNRRGVLTINSQP
NINGKPSSDPIAGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVQGH
NMTNAQDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSR
MIIKYIHDNYFLVNLVDNDFPLDSCLWQVLDDMFELLDAPPEVLIVVTRNQFLKFFTPTF
RTLLAVLVKSTIVKTRIDRLQMTM
>A0A0P1GKW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tropicibacter naphthalenivorans|TrEMBL
MKRPDISFEFFPPKNIEGTFRLWDTTQVLAPLNPSFVSVTYGAGGTTRDLTRDVVATLHK
HSGLRTAAHLTCVDATREETLKIAQDFADVGVTDIVALRGDPPKGSSGFVPHPEGFANSV
ELIEALAATGNFTIRVGAYPDVHPEAANAKADIDWLKRKLDAGATEALTQFFFEAETFFR
FRDECAKAGIDHAIVPGILPIENWKGARRFAESCGTKIPAWVIEAFETAERDHRTDLLAT
AICTELCSELLEGGVEKLHFYTLNRPELTRDVCYALGVTPETKLENVA
>A0A2E7PNA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MMMARESKLCSTGVDQSRPSVSFEFFPPKTPEMEQTLWGTVCGLAPLDPAFVSVTYGAGG
TTRERTHETVSRIIREAGLTAAAHLTCVDASRGEIEDIARDYWDVGVRHIVALRGDPPEG
QGGYMPHPDGYAYAADLVEGLRAVAPFELSVAAYPETHPEALSADFDIDNLKRKVDAGAT
RAITQFFFCNDTFLRFRDRIAAAGVSIPLVPGIMPVGNFKSMRRFAAKCGASVPDDMSMA
YEGLDDDPAGRAEVGARLASKQCLDLRARGVNDFHFYTLNRAELTRRVCANLGVLDHNVE
GMSR
>A0A1Y2TKD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypoxylon sp. EC38|TrEMBL
MHINEMIAEAEKTGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDITWGAGGRIA
ELTCDMVVQAQAYFGLETCMHLTCTDMGEEKINDALRRAYKAGCTNILALRGDPPREKEK
WVASDGRFQYAKDLVTHIRKTYGNHFDIGVAGYPEGCDDNKDEDLLLDHLKEKVDMGATF
IVTQMFYDADNFIRWVGKVRERGITVPIIPGIMPIATYASFLRRANHMNCKIPEEWMAAL
EPVKNDDAAVREVGKTLVAQLCRKIMSAGIVHLHFYTMNLAQATRMVLEELDWMPTSTRP
RKQALPWKQSLALGRREEDVRPIFWRNRNKSYVSRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKRWGEPKSVQDIASLFVKYIQRELPSLPWSEAPLTSESDSIKDDLIK
LNQRGLLTINSQPAVNGVKSTHPVHGWGPSNGYVYQKAYLELLVSPDLFPEVIRRIEANP
DLSYYAVTQSGKFTTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGMDW
AHCHDADSPSRVLIEKIMNEWYLVNIVNNDFHQPRTIFELLDGLTVKDIDVPVTVSQVSV
QSNGIHKEANGVSTINGHGAPATA
>A0A1G3KVN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. RIFCSPHIGHO2_12_FULL_65_19|TrEMBL
MTSNLNSLAEARRAAASPLFANLEGDIGVSFEFFPPKTEKMESQLWDTFRTLEPLAPSFV
SVTYGAGGSTRERTHATVARIAAESRVPPAAHLTCVEASRAEIDEVARAYWEAGVRHIVA
LRGDVPGGAPYRPHPEGYANAIELVAGLKAVAPFEISVAAYPETHPDADCPQSDLDNLKR
KLDAGATRAITQFFFSPDSFLRFRDAAAAAGINAPIIPGILPVSNVSQTRRIADMCGTAI
PAWMVSLFDGLDDHPAARQLVAATVAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVANAKDQAA
>A0A3D5UU54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
EPVAHLTCVGASKAEVDDVIRAYWDAGIRNIVALRGDMPELGAPYQAHPEGYQSTPELIE
GIRKIADFNVIVSAYPEKHPESESIEADIELLRRKIDAGATRAITQFVFDTDQH
>A0A1X9LBG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis aeruginosa PCC 7806SL|TrEMBL
MTTRLRRAVQDREFLITAEITPPKGGNASHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPQARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFECLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDHI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDLAGIPPIHN
>A0A1V4B403|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Canicola haemoglobinophilus|TrEMBL
MSYSKSLDTLNQHIADINGKIDVSFEFFPPKNEKMENLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKHIKQETGLEAAPHLTGIDATSEELKAIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDVDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPSWMAKMYEGL
EDDQTTRNLVAASIAMDMVRVLSREGVKDFHFYTLNRSELSYAICHTLGLRPSL
>H0YVV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Taeniopygia guttata|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCHQTKDEITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFVISQLFFRSETFLK
FMKDCQAIGIACPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLNSPTPQ
>A0A087B4M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium cuniculi|TrEMBL
MPIFSLEIFPPKRTAPVGTIYDTLDGLQGLKPAFISVTYGTGRSADRTATARIAHTVRSE
YGIDAVAHLTAQYLDEDAALEALDMFDQAKVSGILALRGDRDPEREPAGVFAHASDLTSF
IREHRPDMKVYGACYPEKHPQAATLQEDVDNLKRKVDAGCTHLISQLFYDNEDFLRFRDL
AVAAGVDVPIEAGIMPVTNQRSVLRMANMCQSRIPPALARMLERWADEPATLKDAGILYA
SQQIGNLVANGVDGVHLYTMNRPCVSRRIWANVRSLFDQA
>A0A5F0AB39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. 3H14|TrEMBL
MSSETETSGTPRVPFSFELYPPRSASSEEALHDTVRRLAAAGPDFLSVTYGAGGSTGGRS
LDVLRFIRTQTDVEPLAHLTCVGNSYAGAATLIREFLDAGILSFLALRGDPPTGQTDDDL
GDLESAAQLVQLIDRVQAERAPYEEAPVPGLPGAARVDPRRKVNIAVAAFPKGHPRATHR
TQDVEALLAKQAAGATFAITQLFFHPDDYLAFVERARSAGVTIPILPGIMPITSPARLTR
VLELTGEDLPSELAIALDVEPTAEGRRDIGIEWAARLAREVVAGGAPGVHLYAFNQHETV
LTVLAEAGILPALRH
>A0A2E3KE33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSVTKKEIASLVSDFSIEVTPASADRVEAFADHLVPGTSINVTFLPGSSFTDTIRVSRRI
HGEGFKPIPHLAARNFESSKALEQSLDDLTSLANVEEVLIIAGGLDSPLGPYHSTMQILE
SGLLEKYSIKKIGIAGHPEGSPDISNSDIDAALNDKNAWARNTDIEVYIATQFCFEASVI
LDWEARIKKLGNTLPIHIGLPGLATLKTLLKFAQMSGIGPSMRVLTRQTKNLAKLVMTQE
PDIVITDLTSRIAIAPDSLIKRVHFYPFGGLAKTAAWANSVVNEQIEMKPTKGFNTYIDY
>A0A8C1Y8R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADAGWQSSKSDSSGVSNSGESSKESSRXYGCVPGGNESFLFLCVRFDRMGSGGPL
FIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITAHLNKAKRLG
LKNIMALRGDPIGEDWVEEDGGFNYATDLVKHIRCECDDYFDICVAGYPTGHPEAESYDE
DLRHLKEKVDAGAHFIVTQLFFRAETFLKFVKDCRAIGITCPILPGIFPIQGYHSLRQLV
KLSKLEVPEEIMQVIEPIKDNDAAIRSYGIQQAVEMCKVLLASGEVPGLHFYTLNREVAT
IEVLRQLGLWAEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRW
GNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITGQTNPSGHK
VMCLPWNDDPLAPETNLLKDELEKVNCRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQ
KAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVQVNHQHSLQDP
>W7CIK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria weihenstephanensis FSL R9-0317|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARIAAPSL
EEIKRSFREQLYCLLLEGVDAILLETYYDLEELKTVLKITRETTDLPIVANVSMHEPGLL
QSGQTLASALQELADLGADVVGANCRLGPYHMSKALESVPLLENAYLAAYPNASLPQMDE
GKVVYQTETDYFEQYSEIFRQEGVRLIGGCCGTTPDHIRALRRGLKSIKPVTSKVVHPIL
ELAELDAAEDAGVRLTDKVKEQYTVLVELDPPRTFDTAKFFEGAQKLDAAGVDAITISDN
SLATPRISNMALAAILKQEYDIRPLIHLTTRDHNLIGMHSHIMGFHKLGIQDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALVDAGITVPVFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREADKSGTGREEGMAIAKEILDAICEHFNGVYIITPFLRYDLSIE
LTKYVQSKEKISEQTV
>A0A8C2GZU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCECDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGAHFIVTQLFFRAETFLKF
VKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNCRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPPETQEEGSQS
>A0A2N5MFM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. V5-8f|TrEMBL
MNFLEEIQSRILIADGAMGTLLYLHGIDRCFEELNISDPDKVKSIHEAYIKAGADIIQTN
TFGANYLKLSRYGMEEEIKKLNEAAVQIARQAVTDKNFVFGTIGGVTAFKKTAYSIEDLK
RNFREQLYILLNANVDGILLETYYDFEEMTNVLKIARKETDKPIIANMSLHEPGVLQDGT
ILKKAFQHLADLGANVVGLNCRLGPLYMIQSLEKVPLLNNAFLSVYPNGSFPGLDDGQIT
YESDVSYFTQCALEFRKLGARLIGGCCGTTPKHIEAISKAVSHLAPITEKLVEDEPEVII
LPDRKGRKYEPLQSIVKEKHSIIVELDPPKQLGINKFLQGAQALKSAGIDALTLADNSLA
NPRISNLACGSIVKNQLELRSLIHISCRDRNLIGLQSHLMGLHTLGLTDVLAITGDPSKI
GDFPGATSVYDLSSFDLISLIKQFNEGLSYSGKSLGERTDFSVAAAFNPNVKYLDKAVKK
LEKKIASGADYFMSQPIYSEELIQKVYEETKHLPTPIYIGIMPLTSSRNAEFIHNEVPGI
TIPDKIREAMSKAGGNKEQARNEGLAIAKRLIDAAYDLFNGIYLITPFLQYDFSVELTAY
IKQKERDIIDG
>A0A0G9KX01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter butzleri L355|TrEMBL
MFKTLIQKLQEDKYLTLETTPQHEPSMHNIIEKIKKFNLQDKIDGFSCTDNPLAKLRYNS
LFAALKLQQEFEKPVIATMTMRDRNKIALQSDLLGANDFDVRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGHPFKIEPKQIFPFAVVNSYAKNFSSLEKKMHLKI
QNGAIGIITQPIFDIENAQKLLESFDIAKENVEGDKRKSQLIFGIFPVTKLRTALFLSAQ
VPGIHVPQFWIDALEKAHNIGEEEEYKVGMELSNNLFKELNKLHPKIHLMTANRFDVANE
IIS
>A0A031JWP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium resinovorum|TrEMBL
MTASPRAAETPIFAGLPGDISVSFEFFPPKSEKMEEQLWDAITQLAPLDPAFVSVTYGAG
GSTRERTHATVSRIVKETALVPAAHLTCVAASKGEIDEVVDQYWEAGVRHIVALRGDPPP
ADGGRFVPHPEGYASAAQLVEGIRKRHDFEVSVAAYPEVHPEAVSAEADLDNLKRKIDAG
ATRAITQFFFSTDAYFRFMDKALAAGITVPILPGIMPVTSFAAIRRMSGNTEIPGWLETM
FDGLDDRPGPRALVAAVAAADLCKRLYEGGSRDFHFYTLNRAEQAYAICQLLGLRPVKEL
VA
>A0A0M0GQ59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rossellomorea marisflavi|TrEMBL
MNTLLDALSEKILIADGAVGTLLYSYGVDRCFEELNLSHPEEIINVHKQYIEAGADIIQT
NTYGANYSKLSRYGLQDQVKEINEAAVRLAKKAAGQGTYILGTIGGIRAINQHISLEEVK
RGFREQLYCLLLEGVDGILLETYYDFEELKTVLQIVKKETDLPVIAQVSMHETGVLQNGM
DIKDALGELELLGADIVGINCRMGPFHMVKSLEGVPLPKSSFLSVYPNASLPNYEEGRFY
YAAEPDYFGDISNELRLQGARIIGGCCGTTPAHIKAVKERLISREPVKEKKVKTQELIKL
KDPHIQKNLLHRKVKEKKTLIVELDPPKHLDTGLFFQGAKALKEEGIDAITLADNPLASP
RVSNDAMGTLVQQKFGLDPLVHITCRDRNLIGLQSHLMGLHTLGIHNILAITGDPAKIGD
FPGAASVYDLSSIELIELIKQNNDGLSFSGKSLRQRTNFSVGAAFNPNFRHLDASVKRLE
KKQHAGADYFISQPVFSCEHLVQIAEATSHLHAPLFIGIMPLISSRNAEFLHHEVPGIKV
PDEARKLMKEAEGDALQSRAVGMEIAKELVETAMELFNGLYIITPFMRYDMSIELIRYAN
LIEKEKREVPYDHNIV
>A0A8C2KYV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGKDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIITQLFFRAETFLKF
VKDCRAIGISCPIVPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNCRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKVMRSRCGLNSGTSTT
TTSSSTWWTTTSRSTAACGR
>A0A2R6ID63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QS_5_68_33|TrEMBL
MSLDTPTTADGARALLADPRFELMPFDSFGDQMVHLPDGATIAITTSPTLGLGATIEWTE
KAAAAGYEVVPHVAARYVEDDDHLDEVAGRLVEAGVDDVFVPGGDREEPAGEFESAHDLL
VALEDLGYEFDGVGITGYPEGHDFLSDETLQDAMAKKAPHATYITTQLCFDPADIVTWIE
STRERGVELPVEVGIPGVMKYQKMVGVAQKVGVGDSISFVQKTTGLVGFIRQLVGSRGKY
EPDKLIDGLAPHATDPEYGIRGVHIYTMNQVPDTEDWRRGRLE
>A0A8C1WDH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADIGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDRW
FSLEFFPPRTAPGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGKDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIITQLFFRAETFLKF
VKDCRAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEESVYEVFTNYITSQTNRNGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGV
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGRNTTNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFTLLDSPQETQEEGSES
>A0A4Q9GV50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquabacterium lacunae|TrEMBL
MSDFASGPLPISLEFFPPKTPEGADKLTAVRQQLYALKPEYCSVTYGAGGSTQDGTIQTV
RAILKEGHDAAPHFSCIGASKASVREQLAQFKAEGIKRLVALRGDLPSGYGGFGEFKYAS
ELVAFIREETGSHFHIEVGAYPEMHPQARNPQADLQAFVTKVKAGADVAITQYFFNSDAY
FRFVEDVQALGVDIPIVPGIMPITNSSQLMRFSDACGAEIPRWIRTRLEGFGDDKASIQA
FGLDVVTDLCEQLRAVGVPGLHFYTMNQSGPVKAICEQLGL
>A0A3E2W0H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium innocuum|TrEMBL
MKISDIYNKKKSLSFEIFPPKKDSELENIDETLKVLCELNPDYISVTFGAGGTSNCNRTI
ELAKKIKYEYHIEPVVHLTCLHYDKSEIDKFAKILIDEEIQNILALRGDKNPSIQEKGVF
KHASDLITYLKSKHDFCFLGACYPECHPESDNKINEMKHLKKKVIAGTEILLSQLFFDNE
QFFSFVEECRIADINIPIIPGIMPVINTSQIKRMVTLCGATFPERFQKIILKYENNKKAL
FDAGIAYALSQVIDLLANDIDGIHLYTMNNPLVASKICEGIRNII
>A0A173X0H8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia inulinivorans|TrEMBL
MRLTELLNKDEVTISCELFPPKQGAQLENYKNIVKDMAALKPAYMSVTYGATGGTSDYTV
KLAEEVRNNNIPALAHLTCASSTREKVASVIEELKAANIENILALRGDIPANADFPLPDQ
YKHASELIADIKAQGDFCIGGACYPEGHPEAATIFEDLDHLKEKVDAGCEFLTTQMFFDN
NILYNFMYKALKKGIDVPIVAGIMPVTNASQIKRITSLSGNMVPPRFLAIVDRFGDNPAA
MRQAGIAYATEQIIDLIANGVNHVHIYTMNKPDVAGEILENLSNIYVR
>A0A1Y6J3H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio mangrovi|TrEMBL
MGYSYAGHIDALNQNISELSGTLNVSFEFFPPSTPQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLIAAPHLTCIDATREELIQIADDYWDNGIQNIVALRGD
IPPGGGKPDMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVECYLRFRDRCVSAGIDVEIVPGILPVSNFRQAARFAAQNNVKVPGWMSKQFD
GLDDDPTTRQLVGASQAIDMVRILCREGVKDFHFYTLNRAEMTYALCHTLGIRPQN
>W7WUD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp. T4|TrEMBL
MAAYPEVHPQAKSPESDLQAFATKVRAGADSAITQYFYNSDAYFRFVDEAHKLGVDAPVV
PGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDIASIKAFGLDVVTDLCDQLRNAG
VPALHFYTMNQSVATLEIVKRLELG
>D6SZQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis 5-1|TrEMBL
MPYKPKFSLEVFPPKRTSPIGTIYDTLDGLKGLDPDFISVTYGTGKLQDRTATARIANTI
RSEYGIDAVAHLTARYLDYDAVDEALEMFDNAGVSGVLALRGDVIAGQESAGVFEHASDL
VYYIRSKHPDLPILGACYPEKHPEAESLQADIDNLKRKVDAGVTHLISQLFYDNEDFLRF
RDLARAAGINVPIEAGVMPVANASQVKRMTSLCASRITSQVSAMMDRWGSNADCLRDAGS
IFASQQINDLIAEGVDGIHLYTMNHPGIARRIWANVKPLFTKIG
>A0A1M7YA61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfopila aestuarii DSM 18488|TrEMBL
MTFQKRLAAKEFVVLAEMHTPKGVNISRLVNDARKVKGKVDAVVIPGMDNGIMRMSALGG
GVLMQQQGIEAIMHVYCRDRNRMALQGDILAAHVLGVQNLIVAHSEDITEGDHREAKPVN
DIDEVQLLEAIGKLQKGKDMEGFELDGIPSFNTGCTFGPYTDPKSMEAQLKLAKAKVEAG
AKYIITPPVFDMEHFKGFYAKVKELGVPVIPTVFLIKSLAIAQYIASTDPGAHISEDVIS
RIRKSKERELEGIKIAGETIAALRELAQGVMIQTLGWEYKLPEILDAAGI
>A0A061QKH2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|alpha proteobacterium Q-1|TrEMBL
MTHHQPWIKPLGQPLFTGDLSAVDVSFEFFPPKTEKMEERLWAAVKMLEPLAPRFVSVTY
GAGGSTRERTHKTVRRLLTDTNLKPAAHLTCVGATRDEIDAIIQDYKEAGVKHIVALRGD
APDPSTGYRATPGGYENAADLVAGIRKIGDFEISVAAYPECHPDSPNLAADLDNLKRKVD
AGATRAITQFFFEPDQYFRYLDHVRSYGIDVEITPGILPVTNFEQLKRFAASCGASVPRW
MADLFEGLDDHPQTRSLVAATVASELCRRLQAGGVNSFHFYTLNRDELTYATCHMLGIRP
ARTADLPKDINR
>A0A0M2LT44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Ag1|TrEMBL
MTLSINQLEEARRALDAPLFANVAGDAEVSFEFFPPKTPAMEATLWKSMATLAPLAPRFV
SVTYGAGGSTRERTHNTVARIARETSIPAAAHLTCVEATREEIDAVAEQYWAAGVRHIVA
LRGDPPRVGERYAAHPGGYENAAALVEGLRRLHPFEISVACYPECHPDSGDAAIDLDNLK
RKMDAGATRAISQFFFSPDVFFRFRDAVAAAGIDAEIVPGIMPVSNFAAVQRMSKMCGTD
VPGWMEHLFAGLDDLPDARQLVSATLAAELCRKLYAGGVKQFHFYTLNRAELSFAICHLL
GLRARPEVARVAA
>D0YUL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobiluncus mulieris 28-1|TrEMBL
MASGVDWVAPDAGGVLDTPGAPVAFTSVSRGANPKSSRNPTRPVRVSFELYPPRNPDPFS
QAWAGIDRLLDAHPDYVSVTFGTSNSTSASSQSVLAHALQRLGRPVLAHLTCVGKTRTEL
STTITEMLDIGVRDFLALRGDNPKGSVNWEPAPGEFSRASQLVTLLREVAAEYLGDARAI
SIAVAAYPAGTVSARTNAVAALAEKQSAGADFAITQVFYNADDYGALLDSATYQGVSIPI
IPGIIPFTDAARLQRLEGLTGVSVPSRLQAISEISDPEERFLEGLSATLDFVNDLIQAGA
PGLHFYTFNRPRPVLDLVEHLRSRGFTHVDEDSSSELLDLMNAAMQRFSP
>A0A1Q6HK50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. 43_108|TrEMBL
MTVAEIIKNAKKTAFSFEVLPPLKGTGTDALFQTIETLKEFDPQYINITTHRSEFVYKEQ
ADGTYLRSSLRRRPGTVAVASAIKNKYGIKTVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKDDVRFKPVKDGYSHATELIGQINQFNNGKFIDGSEIVSIKDKFTYGVACYP
EKHDEAPNLETDLEYLKKKVELGAEYAVTQLFYDNSKYFKFVEMARNAGINIPIIPGIKP
LTKRSQLNIVPKTFHVDIPQALSEEARKCKSDEEIKQLGIEWCTNQCLELMKNGVPSIHF
YTVSAVDSIRKVAERIY
>A0A2U2S6P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MESVTDLKEYLYSSGQPLLSDGAMGTQLHARGVSFDECFDALNLTQPDLVAQIHLDYLRA
GSDVIQTNTFGANRYKLSLHGLEKELRRINQQGVEIAHQAARSAAKRIFVLGDVGPLGIR
LAPYGRVQPEQARQAFCEQIEALLEAGVDAILLETFSDLLEIRVAIEAVRQLSDVLVIAS
MTFTRDDVTLLGDTPAQVARQLFETGADVIGVNCSGGPAQVWRILRQIGQTLLTSHKALP
PLSAMPNAGWPEQVGGRIMYPANAAYFGEYALAFCEVGARLVGGCCGTTPEHIAAMRAAL
DGQTVGCAPSVSELSLPVEVEDTHVEMEAPSRLAKKLAEGKFVISVEMDPPRGLSTHKLL
AGASLLSEAGADVINIADSPMARMRMSPWAVCELLQRTFDIETTLHFPTRGRNLLRVQGD
LLAAHALGIRNVFVVMGDPTSIGDYPDAMDNYDLVPSGLIKLIKQHLNVGLDQAGGELGQ
PTQFFVGCALNLTPTDIRQEAKNLRRKLEAGADFILTQPVFLPEQAEAFLRHYQEQYGEL
KTPILAGVLPLYSYRHALFLHNEVPGIQIHEETLERIRKAGEDAPRAGVQVALELIEQMR
AWASGIYLMPAFHRYDIAAEIIEACRKA
>A0A0H3JUF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus (strain MW2)|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIHEGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDNAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A7V5BPC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MQFKDIYRTAQRPVLSVELFPPKTEKGWTNLRKELAHIMAHPVGFVSVTYGAGGSTRDNT
LKLVKEVRDRYDVTTVPHFTCVGASRQAILDFVDRAIAEGAENLVALRGDPPRGQTEFIP
APDGFRYAYQLVAFLKAHYRDRLSLAVAGYPEGHIETRDLATSIEHLKMKVDAGADLVIT
QLFYDNADFFRFREMAVRAGITVPIVPGLLPITKYSQIDRITKLCGASIPTDLRKLLLSF
EDGSPDQQMAGIAAAIDQAGELLENDVPGIHIFTLNNSLATAHMVEALGHYFE
>A0A420N9G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDDVKGDDERVKMVGVDIVSELIDKIKTIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSNGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A7Z9ZHG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MKAGSNLEAVLERGAFAVTAEIGPPKGTRREVIEKKAEALKGCCDAFNVTDNQTAIVRLS
SLAACIMLKQLGLDPVLQITCRDRNRLAIQSDVLGAIAFGIKNILCLSGDHQKFGNHPTA
KNVFDIDSIQLIQTLKKMREEKKFLSDDEFSGDAPIFIGAASNPFADPFEFRVARLAKKV
KAGADFIQTQGIFDVPKFRKFMEMVCDQGLDEQVHILAGLIPMKSAGMARYMRDYVAGVV
VPDELVTRMKGAKDAKEEGLRICLETIEQLREMPGVHGIHIMAVGWEEIVPVVVEEAGLL
PRPSFQGAGHG
>A0A859RLT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella michiganensis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELCTIAKDYWDSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFRQAKKFADMTNVRIPTWMAKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7C3QSC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSTIPQTVSLAAEFRKALSERALVADGAMGTMLYSKGVFINQCYDNLNLAQPALVKEVHQ
EYVKAGAEILETNTFGASRFRLNAFGLGEKLRAINQAGVKLAREAAKETAYVAGAMGPLG
VRIEPLGPTSFEEARAAFREQAEALAEAGVDLIVLETFGDLDEVKEAVRAAREVVGEEMV
IVAQVTIDDFGNMPDGSSIETYVRALDESAADVIGLNCSVGPKPMLETIEKMMRFSAKPM
SAMPNAGNPVRVEGRNIYLCSPEYMAQYARRLLWTGVRIIGGCCGTTPDHIREMRSEARS
LQPGVKRLSVTVEEPKAKAQAMAPAPAGKKSQLGAKLAAGTYVAFVEILPPRGVDASKEI
AGAKLCKEAGIDCINVPDGPRASARMSAQVCCQLIQRDAGIEAVLHFCCRDRNILGIQSE
LLGAHAAGIRNLICITGDPPRMGAYPNATAVFDV
>A0A7H4M2S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella michiganensis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAKITGIAGFAISLRCVAT
CRLAAVSRICTRPTW
>A0A848X0V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHIQDIFSKHRTTFSFEFFPPKTEAASEALYSTIAELEDLKPSFVSVTYGAGGSTRELTH
DLVVRIRETTSIEAIPHLTCVCHQEDELREILERYAAAGVGNILALGGDPPRDVGEEYDR
SRDAFQHAAGLVRFIGQFNESGVHEDSRGFGIGVAGFPEGHPATPNRLKEMDYLKAKVDA
GADYIVTQLFFENRDFLDFRDRCELAGITVPVIAGIMPISSKKGMDRMADLAAGARFPAK
LLRSLNRADDSDPGAVERVGIHHATEQCLDLLENDVRGIHFYTLNKSHATREIYANLGIR
DTEGL
>A0A7V8BWT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPLFTPGRRWQPPYYPFKREPFGRRMLARVERWVKGPLWGCRMCGNCLLQETAFICPMQC
PKGARNGPCGGSTSEYCYVDHTRPCIWYEIYERAHKMGREEMLLEVLPPLDWDLVGTETW
AGVVKRVREVGVSQFSRAMVSRHPGKRAKMWDSVFRTIRQPLWWEGDAEYHPPAYSKPVS
QLEQRLHDGEFVVTAEVAPPLSTATGKLCRNVDMVKPYVAAVNFTDNPSATPRMSSLACS
VMAIQNGAEPVMQIAARDRTRMGLQSEVIGASTLGVRNILCLSGDHARMGPPPLGRSDVI
DIDSIQMLWILRRMRDEGRYLDGREIKNPPQYFLGAAAAPFASRPEFQAIREHKKINAGA
QFFQTNLVYDPDGLEIWLNELAKRNILDKIYILIGITPLKTLKMAQYMHHDVPGVFIPEK
ILKRLEAAGDGAQEEGVAIALELIEAIRNKQGVNGIHIMAVGWEEIVPRIVTEAGLLPKD
FSPPVQDTQKTAA
>A0A7W1F278|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MDVASIVTMRLDALVAAKSRTLSFEFFPPKSDRGWHTLEDTIDQLVPLGPDFVSVTYGAG
GGTRAKTREIVEHIQAKTGISAMAHLTCVNATKAELRALLDEYAGAGITNLLALRGDPPK
GETRFTPTDGGCAHASDLIDLIRADGRFAIACAAFPEKHPDAPDRLSDWGHLVEKFSKGA
SAAITQCFFEATPYRELVTWLEGRLGRRPRVIPGILPITNWKSLTRFAAICQATIPDGLR
SAIEPLGDDAVAVRKAGLRWTIALCRQLLADGAPGLHIYCLNHSTAAAEVVTALRTLGEL
D
>A0A6P0UZN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symploca sp. SIO1C2|TrEMBL
MTKPTHNSFRAAAQSGEFLITAEIAPPKGGNPDHMVKMAQALKGRVHAVNITDGSRAVMR
MSPLAASVILLQYGIEPICQVACRDRNRIGLQGDLLGAQALGIHNILALTGDPVKAGDHP
DAKSVFDLESVRLLKIITQLNQGLAANDKPLTDGATDLFAGAAVDPQLKSWSGLQSRFER
KIEAGAQFFQSQLITDFERLEKFMDKIAAGTDKPILAGIFLLKSAKNAQFINKYVPGVNI
PQAIIEQLANAANPLQEGIKIAAEQVKTAGQICHGVHLMAVKREDLIPQILDLAGIVPLN
EAN
>A0A7C5BVT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MALTFREACAKKSFVVTAEVGPPKGTNVAHLKELVGKLREAVDAINVTDNQSAVMKLSSL
AACRLVLEAGGEPILQLTCRDRNRLALQSDLLAAWVLGIRNVLCLTGDHVRIGDHPAAKP
VFDVDSVQLLQLVGRLNAGQDLAGNSLDGAPNFFAGAAVTPGADPLEPQLLKFRKKIAAG
AKFFQTQAVFDLDELKRFLDRAQPDGVTILAGIVLLVSPRMAQFLNENIPGVFVPDRLID
RLASVPKEKRLNEGIRIAAELVRAIREQRLCQGVHIMAIGREERVLEILDAAE
>A0A7V4HPV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MDRPSFPDALRAGVLVFDGAMGTEIYRRHVFTNRSFDELCVSDPQLIRQIHADYCEAGAD
VLTTNTYAANRAALERYGLGRQSGAIVRAGARLARQVADAAGRPVFVAGSIGPLPGQAQY
EALVESMIVEQVEGLLEGGADFILFETQPDRKALVRCATAMRRFPDVPFVLSFALLDHGE
SATGEPVEHLVQPFDGLPMPAAWGMNCGTGPDGLLGPVERAVRLTSLPVVVQPNAGVPKE
VEHRRIYYCSPEYLTSYARRYVDLGAAAVGGCCGTTPDHIREVARAIKPLARARVKPVAL
EPSPEARPKEPTPFAEKSRFAWRLAHGQWVTTVELLPPRGYDLSETVAKSKTLHRHGVDA
INIPDGPRATSRISPLVTAQRIQEEALIEVILHFCCRDRNLIGMQADLLACAACEIRNIL
FVTGDPPKLGNYPHATGVFDADSIGMVAVQKRLNAGIDLGGQAIDPQTHAVIGVGLDPTA
LDEARELDRFRRKVEAGAEFAITQPVFDPDALLRFLDKVQHHNIPIVAGVWPLASYRNAL
FMKNEVPGVVIPDWILDRMASVSSREDQLKTGIEIARQSVARIRDRVRGIQVSAPLGRIA
NALAVIED
>A0A1Y6CYN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomagnum ishizawai|TrEMBL
MRSQQQYSQVYSLEFFPPKTPEAETSLNNTLAKLAPLRPKFCSVTFGAAGSTREKTFETV
VNLQTAYGLEAAPHLSCVASTRDNMREVLHAYQSQGIRHIVALRGDMPSGMMSAGEFRYA
NELVTFIREETGDHFHIEVAAYPEMHPQAQGIEADLKNFKRKVDAGANSAITQYFFNPEA
YFRFIDDCEKLGLDLPITPGIMPITNYTQIARFSEMCGADIPRWVRKRLEALGDDRAAIR
AFGLEVVSDLCRRLLEQGAPGLHFYTLNQAEAVLGIWKNLGLESA
>A0A353DII6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MEILSLLKAPRPTLSFEFFPPKDDAGADDLLGIVDDLGKLNPAFVSVTYGAGGTTRGRTR
SLVQRIMKETSVPTVPHLTCIGHSEDEISEILHHYSKDHVSTILALRGDPPRNEPNYDRR
KDDFKFAADLVKFIKNHNHPIEIGVAGFPEGHPATQNRLKEMEYFKAKVDEGADYICTQL
FFDNHDFLDYRDRCALEGIDLPIVAGIMPITTISGMKRMAELAEGSRFPATLLKALYTAG
NDAKAIRQAGVQYAIHQCQELIDEGVSGLHLYTLNKSNATLTIANSLEF
>A0A5C7F556|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lewinella aurantiaca|TrEMBL
MRVTDYFDQAKDKTLISFEVLPPLKGGSMQAIFDTLDPLMEFKPPFIDVTYHREEYIYKK
RASGYYEKSSIRKRPGTVGICAAIMHRYGVDAVPHLLCGGFTRQDTENALIDLGFLDVQN
VLALRGDARKFEGKFIPEKEGHHYATDLVKQIAAMNKGEYMDDLTDNSEGSHTNFCIGVA
GYPEKHFEAPNMDIDLRYLKEKIDAGANYIVTQMFFDNQKYFDYVDAVRAAGIDVPIVPG
LKPLTKLYQLNSIPRLFYIDLPDDLVKAISAAKNGEARRQVGIEWSIAQSKELKERGVPC
LHYYTMGDSSTIQAIAKAVF
>A0A3D2K375|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
DRSGDAFYHAADLVRYVKKFNHSGIHPDKRGFGIGVAAFPEGHPDTPNRLLEMDYLKSKV
DEGADYICTQLFFDNHDFFDFRDRCSLAGINIPIIAGIMPITSTSGIKRMAELAAGTHFP
AKLLRSLNRAGDKRESVKRVGIQHAAEQCAGLLDGGVDGIHFYTLNQSRATREVYASLGL
A
>A0A3L7TSY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MHLGDALSETSRLARQGPAVSFEFFPPKTEAGWAPLFRTIADFAELSPEFVSVTYGAGGT
TRDKTHALVLRIRRETSIEPVPHLTCIGHTKDDVRRILELYAQNGVETILALRGDPPVGA
RFHSLGDFQQASDLVRFIRVEGARLGVHGGRGFAIGVAGFPEGHPETPNTLHQLDHLKAK
VDEGADYIVTQLFFDNHAFHDWRERCTLAGIRVPITAGIMPIPSITGMQRMADLAAGTRF
PAALLSQLSRAANDARAVEDAGIAWAEQQCRDLVAHNIEGIHFYTLNKSDATRRICKALN
LPCTKSRA
>A0A5J6L9P7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium lushaniae|TrEMBL
MTGKDIPGLEEARDTIPAGTKINVTFLGNEDLDMRVAAAKAVADMGFVPVPHISARRLSS
QGQLEEFLGRLQEVGATDHVFAVGGDPAEPEGPYPDSLSVIRSGILQQYGVKEVSIAGYP
EGHPDIPADVLWRHLEDKSAALKEQGLDAVILTQFAFDTDPVTAWIQAVRDRGIDTEIRI
GTPGPAGVKRLIGFARRFGVGANAMIVKKYGFSLTNLMGTAGPDRFVTDLAALLAQNPAS
GNVRLHFYTFGGLLATSKWAGEYVAARS
>A0A259M894|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. 34-60-7|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LSLHKQGISTAPHLSCVGGTREEIGELLDVYKDNGINRIVALRGDLPSGMGAAGELRYAN
DLVAFIREHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIERLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRQ
FGEEVVTRMCETLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A5P9ITC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. THAF5a|TrEMBL
MNNLCRATPPEERCRGCLALARPRYELLPLSTLAEAAHQLPPGAWVTVTCSPRHGIERTL
EAAEWLAREGFCTVPHLAARLVRDHAHLEGITGRLAAAGIDEAFVVGGDAPRPAGDYADG
LALLEALSRLPGRPARLGVPAYPEGHGQLEAGLLQRDLDAKARLADYAVTQMCFESAPLL
DWLRRQRAGGLSLPVYAGIPGVIAHARLLSVALRIGLGPSTRALGRQRGLLGRLLRPAVY
RPEALLHGLWPSLNDPGGFAGLHVYSFNQVGPSRAWLEALCARHCAGQAIVPVLSSSADS
GAGIVKPAGRG
>F0IFF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 338 str. F0234|TrEMBL
MKVTEHIARAKGETLFSFEIIPPKKGNNIEELYKNIEPLLEFKPPFIDVTTSREEYFYKE
YPSGLLEKKIVRMRPGTVGICSAIQHKYNVDTVPHVLCGGFTKEETEDLLVDCFYLGIDN
VMALRGDAMKEEKYFRPTKSGHTFALDLVKQIDNLRRGIYLHDTLENNAGMDFCIGVAGY
PEKHIESPSKTFDLEKLKEKIDNGANYIVTQMFFDNRKYFEFVEKARQIGIQVPIIPGIK
PITIKKHLNIIPQAFFLDLPEELVKEIEKCKNNNEVKQVGIEWAIEQSKELKRAGVPSLH
YYSMGKSENVIQIISKVF
>A0A4Q5VVQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTEHLQKAEGRTLISFEILPPLKGKGINALWEHLDPLMEYNPSFINVTYHRSETMFKR
KADGTFDKVEVRKRPGTVGICAALQNRYKVDAVAHLICGGFSKQETEDALIDLHFLGIDN
VLVLRGDAPKNEAIFEPEPGGNAYAIDLLHQVQRMNSGLYLEEDLKNAVRTDFCIGVAGY
PEKHFESPNLRTDLAYLKAKVDAGACYITTQMFFDNQKYFDFVKSCRDAGIHVPVIPGLK
PITSRKQLSIIPRTFHVDIPEALANAVLAAKSDADVEQIGTEWLLQQSKELKAAGVPVLH
YYTLGKPKVISDVCREIA
>A0A660VEC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MAEYLSRLHQLLARGEFVVTGECGPPKGADRSVVEKKASYLKGNVDAVNVTDCQTAVARM
SSLATCVILKELGLEPNLQMTCRDRNRIAVTADIFGAD
>A0A4Q5TXH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIDHINQAKGTLVSFEVLPPLKGKGIEALYKHLDPLMEFKPAFINVTYHRSEHVYKKK
ADGNFEKVIVRKRPGTESICAAIMNKYDVDTVPHLICGGFSVNDTEDALLNLQYLGIDNV
LVLRGDAAKNETTFEPEPGGHKFASDLLRQVVNLNAGVYLEEDLKATNKTTFCIGVAGYP
EKHFEAPNMKADLSYLKAKVDGGADYIVTQMFFDNEKYYSFVRDCREAGINVPIIPGLKP
IYNRKQLNMLPKTFHI
>A0A660V0P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MKSGSRLEKVLTAGDFAVTCELGPPQSSNPEAIKKKAEYCLGKVDGVNITDNQTAIVRMS
SMGAGVLAMSCGLEPIMQMVCRDRNRIAMQSDILGAAGLGIKNILCLSGDHQKFGNHPES
KNVFDIDSMQLIAMVKRMRDEKQFLSGDPIKDHEPKLFIGAVANPFADPFEFRVMRLAKK
IEAGADFIQTQCIFDIDRFGKWMKLVTEAGLHKKVHILAGLTPVRSHRALQYMKNEVAGM
SIPDELIKRMETAKEPKEEGVKICLEMIEKVKNMEGVAGIHLMPIGWESITPVILERAGL
LPRPEV
>A0A0Q4KH62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. Leaf32|TrEMBL
MTPTISDLEEARRALDAPLFADLAGDCAVSFEFFPPKTEKMEAALWETVRALEPLAPKFV
SVTYGAGGSTRERTHATVARIARETSMPAAAHLTCVEASRAEIDQVAQEYWTAGVRHIVA
LRGDPPTMGQKFVAHPEGYENAAALVAGLQKLHPFEISVAAYPECHPDSEHQAADLDNLK
RKIDAGATRAITQFFFTPEAFFRFRDAAAAAGIHADLVPGILPVSNVAQVRKFAGLCGAS
IPAWMDRLFEGLDDHPGARALVAATVAAEMCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPKAKPVAVAA
>A0A1F9CTL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_16_58_17|TrEMBL
MKSDGNLEKVFEKGHFAVTSELGPPKGNDVSVIRRKVDFLRGYVDAVNVTDNQTAIVRMS
SIATSAFVIQMGMEPVMQMVTRDRNRIAMQSDIFGATALGIRNIVCLTGDHHTFGNQVNA
KNVHDLDSVQLIDMVRMMRDEGTLLGGEDKIEGEIKLFIGGAANPFADPFEFRALRTAKK
AAAGVDFIQTQCIYDMERFKEWMKMIRELGVHEKVHIMAGVTPLKSAGMARYMAKNVAGI
TIPDALIDRMAKAAKGSEEGIRICVEQIQELREIEGVHGVHIMAIEWEQMISKITEMAGL
LPRPQVE
>A0A2D5XQI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MTRIINRFGTGAPVFSFEFFPPKSDEGAEALMATVLDLQAAVNPDYVSVTYGAGGTTRER
TQQVVSRIQNQIGLPAMAHLTCVAATRAEIDQVVDQLVADGIENILALRGDPPKEQENFQ
APEGGFAHASELIAHLAKRGGLCIGAAAYPESHPESPDADEDLHWTIHKVEQGASFLVTQ
MIFDNEHYFRFSDRLRSRGVQVPMVPGIMPITNVAQIDRFTKMCGVEIPGALSKRMHDHQ
DDPASVMAIGIEHAIEQCRELLARGAPGLHFYTLNRSLATRGILAALKG
>C1CCW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae (strain JJA)|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A3L7TUU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
EELLPNLMNTVEELQRFSPDFFTCTYGAGGSTRDRTLGVLGALKTQHNLRIASHLTCVGS
TVEQLRSYLDEATAIGVDYIVALRGDPPKGETEFKQTEGGLRYANDLVSMLRREYPGLGI
LVAGYPEVHQEAPSAEVDLENLKRKVDSGADAIVTQLFYNNEDFYRFRDRCEAIGIKIPV
IPGILPVISLPSIQRIASMCKAALPQDFVDALSQSDQVDWQFQVGTDFAANQVADLLKSG
IPGIHFYVLNSSKATSKVLDAVGW
>A0A522E4G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
AIDLLKQVINLNNGIYLEEELKGTSSTKFCAGVAGYPEKHFEAPNMQTDLLYLKKKVDAG
AEYVVTQMFFDNKKFFAFEKQCREAGITVPIIPGLKPITTKKQMTVIPRTFYVDIPTDLS
GELLKCKDDADVEKVGTEWLLAQSKELKAAGVPVLHYYTLGKPHVVCNVVREL
>A0A258F9M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium 32-35-8|TrEMBL
MKVTDHIQKANGKTLFSFEVIPPQKGKNIQELYDNIDPLMEFKPPFIDVTTSREEYVYLD
KGNGLLDKRITRMRPGTVGICASIMHKYGVDAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VMALRGDSMKDEPYFRPVEGGNAFASELVAQIANLNRGKYLHDDVVVEHNSDFCIGVAGY
PEKHMEAPSLVTDLKRLKAKVDAGADYVVTQMFFDNNKFFEFVEKARAAGITVPIIPGIK
PLAVKRHLQLLPQVFKIDIPQELIDAVEACKDNNAVRQVGIEFAIQQSKELKAAGVPVLH
YYSMGKSDNIKAIASALF
>A0A3M1RF13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MFDPEALLRFLDEIGEIPIPVIAGIWPLASFRNATFLKNEVPGVVIPDAIMQRMEAAKTR
EDQLKTGIEIARESVERVRERVAGIQVSAPFGKVEIALGVIEG
>A0A4S4AY73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azoarcus rhizosphaerae|TrEMBL
MPKTELSIEFFPPQTPDGAEKLRAVRERLAVLEPAFFSVTYGAGGSTRERTFATVQEIAA
AGHEAAPHLSCIGSTREQLRAILQQYADAGIRRIVALRGDLPSGVGTPGEFRYANELVEF
IRAETGRRFHIEVAAYPEWHPQAKSPRDDLLAFRRKVEAGADSAITQYFYNLDAYLHFVD
EARALGVDVPVVPGIMPIASFSKLARFSDACGAEIPRWMRRKFESFGDDSASIREFGLDV
VTELCQRLLDAGAPGLHFYSMNQADLTLAICGRLGLGPQAA
>A0A842TUE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MDYGCTGGRVKEMTEEYYSKLMEKIMKKEFVYTGELEPEKTTDPEETVEAAKEMIGIVTA
ANVTDGPQAMAYMNSMVASYHVLQAGMEPVYQLTCRDRNRIALVADLLGAYSLGIRNVLA
LTGDHSGVGDNPDSMPVFDLDSGQLAYLIKELMAGKDLRGNPVHKPPKFWVGVAGNPNAD
PLEPEILKIGRKAKYADFVQTQVIYQIDETKAFLKELEKYKSYNGVSIPVQIGIFPMKSY
GVAKYFNDYIPGVSVPQDLLDEFKAVKKGGFSKQEKKEKNAEINVKFFVPFIKELKKTTR
CAGIHVMAVGYAKVVKQIIDEVEGN
>A0A8H5PQ79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella subglutinans|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYDHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGLRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGYYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A6P2RTC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia arboris|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAATATRTICERLVV
>A0A8B8V156|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces paradoxus|TrEMBL
MSIRDLYHARASPFISLEFFPPKTELGTSNLMERMHRMTALDPLFITVTWGAGGTTAEKT
LALASLAQQTLNIPVCMHLTCTNTDKSIIDDALDRCHNAGIRNILALRGDPPIGEDWLDS
QSNDSPFKYAVDLVRYIKQSYGDTFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVD
AGADFVITQLFYDVEKFLAFETLFREQISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
TILSRFPPEIQSDDNTVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SSVLSHIVNESSEEEGEDETGGEIRSIENIPIEDADGDIVLDDSNEDTVANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKNRALELWGTPKTIGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWET
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKA
WRDEAFSIWSEWGKLFPRNTPANILLRQVHRDYCLVSIVHHDFKETDELWEMLLDQA
>A0A5C9CB73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MRWRKLLTAPDLFIGATVNPFVPPFGDRIANLEKKIAAGARFIQTQFCFDLPMLEDFMRL
VRERGLHQRAHFIVGVGTLGSAKALAWMANNVPGVHVPPALLARIAAAPDQKAAAKQVCI
ETIQALARIEGVAGVHVMGHKNEDTLAQIITECGLREHTRLHCA
>A0A1H5TK10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces yanglinensis|TrEMBL
MALGTSSTRTDRAATIRELLASGRRSYSFEFAAPRTEKGERTLWNAIRRIEAVRPTFVSV
TYGAGGSSRDGTVRATDRIVSDTTLTACAHLTAVNHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPMGEWVPHPEGLTYAAELVQLVKESGDFCVGVAAFTEMHPRSTDPAEDTRYFLD
KCRAGADFAITQMFFDADAYLRLRDRVDRAGCTVPIIPEVMPVTNVRQIERFSQLGNAPF
PPDLAERILAVQDDPAAVRAIGIEFTTEMCRRLMDEDIPGLHFITLNHSTASLEIYENLG
LHRRTA
>A0A1A8SKI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius rachovii|TrEMBL
MNVAAPFTVMVNQVQRVDGSWLSCKSDSSGTSNSGGESSKESSRCSTPVLDAVRSDRLRD
KMRRRMESGDQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKET
SSMMIASTAVNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEE
EEGGFNYAVDLVKHIRSEFDDYFDVCVAGYPTGHPEAESYADDLRHLKEKVDAGADFIIT
QLFFRADTFLTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPI
KDNDAAIRNYGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPL
PWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFY
LKSKSSKEAL
>A0A4Q5TNG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
QAYALRPDFCSVTYGAGGSTQAGTFAAVGEILAEGVDAASHFSCVGATRGKVRDQLGALQ
AMGIKRVVALRGDLPSGYGMGGEFQYASDLVAFIRSEMGDAFRIEVACYPEVHPQARSPQ
SDLDAFAAKVHAGADSAITQYFYNADAYFRFVDETRKRGLDIPVVPGIMPITNASQLLRF
SDSCGAEIPRWIRLRLQGFGDDTASIKSFGADVVAELCHRLQLGGAPGLHFYTMNQANPV
LEVCRRSGWQG
>A0A359A0R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Microthrix parvicella|TrEMBL
MAPGTPHSSVPSRPDRSTSAHQDARIDDLLAEGPTLSLEFFPPKTDRGVANLLDTVDELE
DLNPDFVSVTYGAGGSTRDRTRDLVVSANADRNYPVMAHLTCVGHTRSELAELLEDYAAS
GVRNILALAGDPPADGSPAGGDFTYATELVELIREVGDFSVGVAAHPETHPRSPDRASDR
RHLADKLEVADFAITQFFFSASDYFEMVDELTALGVTTPIVPGVIPVTNPVSVARFADMA
KAHRPHELWARYESVADDEAALMEVAVEAAANLAEELLAGGAPGVHLYALNRAEAPLGVG
ARLGWRIRPAVEATDG
>A0A542UKW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces puniciscabiei|TrEMBL
MALGTPSTRTDRARTVRDMLATGKTTYSFEFYAPKTPQGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRTTTVRETQQIVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWIPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFHPESYLRLRDRVVAAGCDTPVIPEVLPVTSVKMLQRVPKLSTALF
PDALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A3E0VK96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Subtercola boreus|TrEMBL
MNLLLASPAAAPGCPKLMHYGPCGGVSADGSCEIAPTPCVFLDRPTVAWPDAAEAASARP
DPLLNGSLGAAPGPALLPSLSPGRRTPAGEEVLAIIRSRPLVMTGLPAVPMDSASIAACA
DIMRDSVDVVLSGDSGRARVQFPPSYRAELIRRNGLRAWLGVNCRDRNRVALEGELLALA
DAGVAGVHCVTGDHTDLGDRADAKPVFDLEGIQLVPRARAAGLLVSVAESPASPPVDRRA
ARLIEKAHAGAEFCLPQYAGETSDLARYIDEVRAGGVDIPFVAGVPVVIDRIGAELLASF
AAAILPAGFIEGILDARDPFEAGIRASVALAEELLELDGVVGIAAAGGAQVGQELQFARA
LARIGAELGGGASL
>A0A7U7G3Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia enterocolitica (type O:2) str. YE3094/96|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>T1K409|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetranychus urticae|TrEMBL
MILHLTRRLIGLNIHILLTQQVWFHKLANMSTSPSLVTNFSQQLQSFKLPFYSIEIFPPS
TESGLNNLKNFLSDIRKYRPLFCAITSKSTSRTSENETGSRFELARMIIKNYGFDILLHL
TCSDMMDSNQGRKILSEAKKSGIKYIFALQGDNFKPAEPREFNHAIDIVKFIRKEFSNDF
IIAVAGYPDGHPSSPSFKQDIAHLKAKVDAGADIVISQFFFNVDTFAKFVRCCRSADIKA
PILPGIFTFSSYKSFTRMINTTKVPVSNELLMKIESKSQADQQIKQFAIKTSTQLCLNLV
NQGLCPGLHFFSLNQDASLHVIEMVEPMIPRTTINQQLLRLSAQLEECVLQSETVIQKNA
SPIIVQEETPKIIC
>G8N716|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus thermoleovorans CCB_US3_UF5|TrEMBL
MGLLDKLKERILIADGAMGTLLYSHGIDRCFEELNLSNPDEIVHIHEAYIAAGADVIQTN
TYGANYVKLARYGLEDEVPAINRAAVRLARQAANGRAYVLGTIGGLRTLNKSVVTLEEVK
RTFREQLFVLLAEGVDGVLLETYYDLEELETVLAIARKETDLPIIAHVSLHEVGVLQDGT
PLADALARLEALGADVVGLNCRLGPYHMLRSLEEVPLPKQAFLSAYPNASLPDYRDGRLV
YETNAEYFEETAKAFRDQGVRLIGGCCGTTPKHIAAMAKALSDRTPVTEKTVKRRAVSVS
VQADRPAPSPLPELARTRRSVIVELDPPKKLGIDKFLAGAKALHDAGIDALTLADNSLAT
PRISNAAVATIIKEQLGIRPLVHITCRDRNLIGLQSHLMGLHTLGITDVLAITGDPSKIG
DFPGATSVYDLSSFDLIRLIRQFNEGLSYSGKPLGQKTNFSIGAAFNPNVRHLDKAVERM
EKKIQCGAHYFLTQPIYSEEKIVEVHEATKHLDTPIYIGIMPLVSARNADFLHHEVPGIT
LSDEIRARMAACGGDPVQAAKEGIAIAKSLIDAAFDLFNGIYLITPFLRYDMTVELVRYI
HEKEAAAKERKVVHG
>A0A7C4XMS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MATDNERRSRLIGGSDIVVSFEFFPPKTPKMEEALWTAVRRLEPLRPDFVSVTYGAGGST
RERTHATVSRLVRETMVVPAAHLTCVQAEKAEVDEVARAYWQTGVRHIVALRGDMPAGPG
VRYTPHPGGYANAAELVAGLKRLAKFEISVAAYPEKHPESPSVETDIDNLKAKIDAGADR
AITQFFFDNADFLRFLERVRARGITVPVVPGIVPIHNFKQVAGFAARTGAKVPAWLARRF
DGLDDDPATTHLVAAAVAAEQVLDLVDCGIRQFHFYTLNRADLVYAICHLLGLRPKPVPV
SKEAST
>A0A8C6L044|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius furzeri|TrEMBL
FSDQKPEIQTYRTPFAVMVNQVQRVDGSWLSCKSDSSGTSNSGGESSKESSRCSTPVLDA
VRSDRLRDKMRRRMESGDQWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAG
DPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITGHLAKAKHLGLKNIMALRGD
PVGSDWEEEEGGFNHAVDLVKHIRSEFDDYFDVCVAGYPTGHPEAESYEDDLRHLKEKVD
AGADFIITQLFFRADTFLTFVDDCRAIGVTCPILPGIFPIQGYQSLRQLVKLSKLEVPEE
ITRVIEPIKDNDAAIRNYGIHQAVEMCRVLLDSGKVPGLHFYTLNREVAPTEVLRQLGLW
IEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGE
LNDYYLFYLKSKSSKEALLQMWGEELKREESVFEVFTCYITGQLNRNGHKVMCLPWNDEP
LAPETNLLKDELEKVNRRGVLTINSQPNINGKPSTDAVVGWGPAGGYVFQKAYLEFFTSS
ENVNALLKVLKKYEPRVNYHIVNVHGRNLTNAHEMQPNAVTWGIFPGREIVQPTVVDPVS
FMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLKSCLWQVLDDM
FELLDAPLETLADGMPGDGSHGDGSHDNGTLAE
>A0A7C5JJB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
NVDWVSITDNAGGHPTLRPMTLGEKFLNSEKEVIIHLTCKDMNRNALESNAWSLSSQGFN
NILALTGDYPQNGYNGNSKPVFDFDSVSLLNMLSKLNEGLTTGIKKKTTLKSTDFFLGAT
VSNNKKNENELIPQYLKLKEKIKNGAEFIIPQVGFDSGKIQELKLFMHDNGFDHIPLVGN
IYLLSKFTSNLFHKNKIPGIVLTDELYNKCQHAATSDDKGKSFFIEFAAKMLNIFKKLGY
KGAYFGGIHNYDNFNRIIEVEKSFSENDNLDFIKELWFPKKNEYFIYKKDISTCLLQKEK
NLKAKNKLSFKSKINYSVSKGFHSLMFKPGAIGYKIGKTISNQDKYKYHLPSWIHIIEKR
SKQVIYDCKDCGDCALQYTGYLCPESQCPKGLRNGPCGGTHDSICEVRDSECIWSRAYNR
LKRDKKENNLLDHTPAFKDNSLVDTSAWANYWLEKDFGSKLNKK
>A0A7C2R670|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MAPLPADAVATRAAEDLAATAAELVSCGSLEMGADTPQDALRIASLLPAGTPVYVNHLPR
RALAHTLPALVALKEAGLDPVPHIAARRIGSRAEAASFLKEAVAVAGVRKVLLIGGDLPE
PAGPYADAAALLRQGLLGDCGLAQVGLAGYPEGHPRIATAALAAALAEKLALAARQGLGA
YVVTQFCFAPNRIVEYCADLARRAPQAPVYVGLAGPTSPVSLLRYAHRCGVSASLRALQA
QGMGAVRLVTHVDPGDQLSVLARHSRMGSASNVVGVHLYSFGGVARTAAWMNERITARSG
A
>A0A8I1NXA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSPDINPHDPGAPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSANPEDVYERAAVFN
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNGKFLSGRKLSTPPHVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFRTYMDKVRELGLHEKVFILCGVG
PLASAKTARWIRANVPGIHIPDAIIARLEGAQDQKKEGKQICIDIINEVKEIQGVAGVHV
MAYRQEEYVAEIVHESGVLKGRQPWKPEMNPADALVAARMNAMREGAEQNQQQLAGIAAQ
HPH
>A0A2E2QI10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sneathiella sp|TrEMBL
MTAGASEDISAPLPPLPGHTSRGRLERVLRAGEFAVTAELNPPDSADPNEVFERGAIFDG
WVDGINATDGSGANCHMSSVSICALLTRVGYSPIMQISCRDHNRIAIQGNVLGAAAMGVN
NILCLTGDGVQAGDQPGAKPVFDLDCMSLLRTIRQMRDEGRFLSGRKITSPPQVFLGAAI
NPFAPPYDFRPYRLAKKIDAGAQFVQSQYCFDIPMLERYMEQVRDMGLDEKCFIMIGVGP
LASARAAKWIRSNVPGIHIPDAIIDRLEGAEDQKLEGKKICIEMLQQVHEMKGVSGAHVM
AYRQEELVAEIVYESGVLKGRKPWKRESNPDFEAVTDAVETVREQINTPIDPAEVVAAVS
EEQ
>A0A661ZSP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
QSIYDTIDPLIEFDPKFVEVTYHREEVEFREHADGSIERKVLRKRPGTIGISAAIKFKYG
IEVIPHIICGGFNFEETENGLIDLHFLGINNLLVVRGDNLPGEKFFRATKGGHQYTSELI
RQIMDLNHGGYLDEELKNTTSTDFAVGVAGYPEKHAESPNIQTDIKHLKEKIDAGAEYIV
TQMFFDNSMYFDFVDRCRKAGITVPIIPGLKPISTKSQLGTLPRTFSISIPEELQLEIDK
CKGNKEARQVGVEWAIIQSKELVSKGAPVMHYFTMGKSDNIRQIAKAIF
>A0A1W9JMW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium ST_bin11|TrEMBL
MNISFEIVPRSLEAFDQQYDFVQTLDKAVNIINVPDIQRFDTRSWELATRVDRRQYRFVP
HFRAIDFKIESGELYRIVEEYALDSVLLVSGDPPEGLKRSFYNTDVVDLIRAVRQRFPNL
NIYAGFDPHRSGVQDECDYIQRKVDAGAGGFFSQPFYDSRMIDIYAEHMQDLETYIGISP
ITSKASMNYWEVKNKVKFPKSFQPDYDWNVQFANSVIASAAANGLNVYFMPIRIDLARYF
GEIKLGG
>A0A5C8BL08|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp|TrEMBL
MTQRVPISFEFFPPKTDAGAEKLRVVHQQLQPLNPEFFSITYGAGGSTRERTLAATNDFN
GKGTPVAPHLSCIGDDKARIAELLDLYQSQGINRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIQRFVDKVNAGANAAITQFFFNPDAYFYFM
DRIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIRAFGHE
VVVKLCERLITGGAPSLHFYSMNNTEPTRQLVIDLGLN
>A0A4R7QAE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gelidibacter sediminis|TrEMBL
MKVTDHIKQANGNTQFSFEILPPLKGQHIQSIFDNIDPLMEFKPPFIDVTYHREEYVFKE
QENGLLKKQVVKKRPGTVGICAAIQNKYKVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKTETYFRPEKDGHEYANGLVQQISALNEGVYLDEELQNSSKTDFCIGVAAY
PEKHMESPSLESDIHFLKKKIKNGAEYVVTQMFFDNQKYFDFVNKCRTEGITIPIIPGLK
PIATKKQLNLLPHRFHVDLPEDLILEIVKCKDNVAVKQVGIEWCIQQSKELQQAGIPVLH
YYSMGKSDNIQTIASQIF
>A0A011NHS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Accumulibacter sp. SK-12|TrEMBL
MITKSPTFSLELFPPQTPEGAEKLRAARAQMALLKPKFFSVTFGAGGSTRDRTLETVLEI
QNEGHRAAPHLSCIGSTRASIRSILEQYRAHGIRHLVALRGDLPSGMARPGSFRHANELV
EFIRSETGSWFHIEVAAYPEYHPQAKSPLDDLLAFKRKIDAGADSAITQYFYNFDAYSHF
IDECQAVGINAPIVPGIMPISSFSSLARFSDNCGAEIPRWIRKRLESYGDDKASIHAFGL
DVVAQLCERLLAAGAPGLHFYTLNQVGLTRTLWQRLGLASAAGD
>A0A523G5S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTQHIEKANGNTLFTLEILPPLKGQTITSIFNTIDPLMEFNPPFIDVTYHREEYVYKE
LENGLLQKQVVRKRPGTVGICAAIQNKYNVDAIPHILCGGFTKEDTENFLIDIGFLGIDN
VMALRGDAVKNETYFTPEKDGHNYANELVSQISDLNKGIYLDDEIQNQAKTDFCIGVAGY
PEKHMEAPSMDSDIYFLKKKIKKGATYIVTQMFFDNEKYFAFVNKCRTEGITVPIIPGLK
PLATKKQLNLIPHRFSAELPDDLIMEVVKCKNNEAVREVGVEWCVNQCKGLIVAGVPILH
FYSMGKSDNIKAIAAQVF
>A0A2A4NNC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSLYKLSRSVASSKKVDVSFEFFPPISDKAEENLWKAIRRIENLSPKFVSVTYGAGGSTR
ERTLRTVKRMVDETNLNVAAHLTCVGASKSEVDGIVNEFKDAGINRFVALRGDPADGIGE
RYIPHPSGYNNGAELVAGLKGISDFDVTVAAYPEKHPESADFATDMDMLKRKVDAGATRA
ITQFFFDNDLYEAYLERVRKAGIYIPIIPGIQPIHNFIKVANFASRCGTSVPQWLAERFD
GIDSDPETRQMLAAAVAAEQVADLATRGVTDFHIYTMNKAELPVAICRLLGIHEKIPETA
SKD
>Q46HM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus marinus (strain NATL2A)|TrEMBL
MKSKLQKRLESGLSAITAEIMPPRGGNTASAISKAIKLKDLVHGFNVTDGSRAIMRMSSL
ALCKLLLEANLEPVLQLSCRDRNRIALQAELLGAHALGITNILCLTGDPVRVGDQSQAKS
VQDFNSIELIKQVTSLNKGIDPVSDLLPDGPTNLFAGAAADPNCRGFDSLRRRIELKKTA
GANFLQTQMVMDPKVLERFCREITEPMKIPVLAGVFLLKSAKNAQFINRVVPGACIPESI
ISRLESSSNPIDEGISIAADQVKSFLGIAQGVHLMAVKAEQQIPIILDRANIN
>A0A2T2VVR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTDHIIKAAGATQFTFEILPPLKGQNIQSIYESIDPLMEFKPPFIDVTYHREEYVYKE
LANGLLEKHIIRKRPGTVGICAALQHKYNVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAIKSETYFKAHKDGHTFASDLVNQVQELNKGHYLDEEILNTSKTDFCIGVSGY
PEKHMEAPSLESDLHFLKKKVEAGANYIITQMFFDNQKYFEFVEKCKEAGINVPIIPGLK
PLATVKQLNALPHRFHVDLPEALIKSVIKCKDNAAVRQVGVEWCIEQSKELKDAGVPFLH
YYSMGKSDNIKAVAEAVF
>A0A4V0X5S3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVIEHIASKDKNVFSFEILPPLKGKGIQSIYNCLEPLMEFKPPFINVTYHRSDFIYKKT
VEGLFQKKMISKRPGTAGICAAIQTKFKVDAVPHLICGGFTIDETEDLLIELNFLGIENV
LLIRGDKMKSEEVFTPEKYGHAYAVDLVKQVVNMNKGVYLEEDLKHATATSFCIGVGGYP
EKHYEALNFNTDLKYLKEKVDAGADYIVTQLFFDNQKFFQFVKACREAGIQVPIIPGIKP
LTNLRQVYNMPRVFYVNFPEAMANELVKCKTDEDVTRVGLEWSISQCKELIQHGFNCLHF
YTMSNPLPAQNIVKQLA
>A0A2W4QUI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKVTEHLSRANGKTLFTIEILPPLKGENIESLFANIDPLMEFKPPFIDVTYHREEYVYKT
KENGLLEKSTTRKRPGTVGICAAIQNKYKVDTVPHIICGGFTKEETENALIDLHFLGLDN
MLVLQGDAIKTESRFIPEPGGHHYASELLQQVVAMNQGRYLD
>A0A2N0L1L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G2|TrEMBL
MKIREILNTTRTISCEFFPPRTAEGIPAVFQAVEGLKTFKPDFVSVTYGAGGSTRAFTEE
ITAGLKEQHQLEVMAHLTCVAQTKDELNQVLERLDRSGIENIIALRGDPPRGQEGFVPVE
GGFQHAIDLVKHIRENYDFGVAAACYPEGHTESPDLATDLKHTRLKVDQGADFLITQLFY
DNSDFFKFIERAGKAGIDVPIIPGILPILSTGQIRRFTSMCGAKLPPKLDQQLEKFSDDD
DAARELGVEYATQQVRELWDNGVPGVHFYVLNRSYSVSKILENLAIPGH
>A0A233S5X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces diastatochromogenes|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFSAPKTPQGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRVNTVKETQQIVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVAHPSGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSAEWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVEAAGCDTPVIPEILPVTSVKMLERLPKLSNAHF
PDALKERILTAKGDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A7W0HGS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus kamchatkensis|TrEMBL
MGLLDDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIESGAEVIQTN
TYGANYVKLARYGLQDDVKKINEAAVELAKKAAKGRAYVLGTIGGLRSTNKSTISLEEVK
RTFREQLYVLLNEGVDGLLLETYYDFEELQTVLSIARKETTLPIIAHVTLHDIGVLQHGM
PLAEALTELEQLGADVVGLNCHLGPYHMLRSLEEVPIPTRAFLSVYPNASLPQYRDGRFI
YETSEQYFEETARAFREQGVRLIGGCCGTTPKHIAAIARALSDRTPVYKKEVKQRHPIVV
QEEKQTTAPSLADIARTRRSIIVELDPPKKLGLTTFLEGAKALKEANIDALTLADNSLAT
PRISNVAVGTIVKQQLGMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSKVG
DFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVKRL
EKKIECGAHYFLTQPLYSEKQIEDVYEATKHLPTPIYIGIMPLTSARNADFLHHEVPGIT
LSDDIRNRMAMCANDRVQSTKEGLAIAKALIDAAFDLFQGIYLITPFLRYDMTVELVRYI
HEKERLAKERTVYHG
>A0A430AJ97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vagococcus entomophilus|TrEMBL
MGESLREALSKRVLVADGAMGTLLYQFGTQRSVEELNLSHPESIQKIHEEYIKAGADMIQ
TNTYAANYLKLERYGLQEKVLQINKAAVENAKAARKNHSVFILGTIGGIYSPGERKLNEA
SIEEIKRSFKEQLYALLLAGVDGILLETYYDLNELCEMLKVAKEATDLPIIANVTMQEIG
VLSSGVTLEHAFEELQTLGADVVGANCLLGPSHMVQVFERVPLKQGRRLACYPNASLPAI
ENGTIIYEKGTAHFALCSEQLRQEGVSIIGGCCGTTPAHTKAICQGLKTIEIVKQKEGVF
SDSKPISNRKKEKGKRICEKVKETCTILVELDPPRTLDTARFFEGIEALQKVQVDKITIS
DNSLARPRISNLALAAILKHRYQISPLIHLTTRDHNLIGLTAEIMGLHELGIFDVLAVTG
DPARVGDFPGASSVRDISSLGLIKMIKQFNQGIAYTGKHLVESSDFRVAAAFNPNVAKVE
RAVQVIKKKQEAGADYIITQPVYDRKILARFAQSLKEAKIDLPIFIGIQPLTSSRNAEFI
HHEVPGISLTDEVRERLQHAEQPKSEGIQIAKELIDEIALYFNGFYLVTPFQEYPLSVEL
VKYIQSKKRS
>A0A7K8RPJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodinocichla rosea|TrEMBL
MVNETQHSCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRRVLQGRRGEVFDRMGAGGPLFIDVTWHPAGDPGSDKETS
SMIIAYTAVNYCGLETILHMTCCNQSKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEE
VDGFNYAVDLVKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVCAGADFIITQ
LFFRPETFLKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIK
DNDAAIRNYGVELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGMWNEDPR
>A0A1Q6ZBH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon 13_2_20CM_2_53_6|TrEMBL
MKLSERAKYHTIVTAEVIPDRVVPAHLPLLDGRVDAITIPALRNGENDPSYPSEFRVTPQ
TRSVASAVIVKKTGFEAVPSLTCRDFRRSDLPLLPVLFKKGLENFLVVFGDPYPNYEIKT
YDFKRAEDLIRGIRSVFDGQRPCIGAVTNQYALDREKEISRTLSKVDAGADYLVTNSAFD
DYYVLDYIDALRSSGLKVPIFVQLSIPHGLNNLLFVSRRFGIPVPESVKETVSRDPLGGG
VQVIARAFAGLRNEVSGIHFSYLFRSHNPIPTYTHLLDAIETDWQLVGSLQATLRT
>A0A836UR34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MFSSKTADFIFTSETTPAVSTNLRQSIDLVLPLVDVADAVNVTDSPNSKARLSSLLVAAG
IKELGLDVILQLTGRDRNRIAIESEVLGALSIGINKVLCLTGDKPRQGGPQVVNEFDSGG
IMGLLNVISNGKLSDGTDIKEPLPIYPGAADDLYFQKDNPQAIDFLKRKISNGAKFIQTQ
YCYDEEICRFYSNLLIANGKTDDLKVLVGMGPLKSARQALWMRENLWGVNISDAIISRLD
TSKNPNKEGLMICHELISKLIDLPGIDGVHLMGPSCESDAADIIKLFR
>A0A844QGD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratireductor arenosus|TrEMBL
MNQFRLSRRPDIGDQIDVSFEFFPPKSDAMEARLWETTERLQPLSPSFVSVTYGAGGSTR
ERTARTVERIIRETALTPAAHLTCVDATREDADQVIRQFLDIGVSRFVALRGDPADGVGT
RYAPHPGGYANAAELVEALARHGAKDISVAAYPEKHPESPDFATDIDMLKRKVDNGAKRA
ITQFFFDNDLYERYVERARRAGIYVPIVPGILPVHNFGQVANFAGRCGAHVPAWLAERFE
GLENDPQTHALVAAAVAAEQVLDLVERGVSDFHFYTMNRADLAFAICHMIGIRANGARED
AKPAAA
>F6BIX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoanaerobacterium xylanolyticum (strain ATCC 49914 / DSM 7097 / LX-11)|TrEMBL
MQNSENLCQKLKNKQFVITVEISTPKGADISNSIEEAKKLYGIADALNITDCPMANMRMS
PIALAHLLQNHLNIETIFHLTCRDRNLIGLQAELLGAYALGVRNILALTGDDPKRGDVPQ
ATGVYDVDSVGLVKIAKSLNDGFDYSGNKLESSTNFCIGTTANPNDLRPESIEKLKTKIE
SGASFIQTQPVYDEEILYGFLDAVKQFDIPVLVGVLPLKSYKMALNLNEKVPGIEIPEKI
IDRLKDGEKGEGIKIAIEFINKIKDKVGGVHIMPLGKTDIVVDIVNGVKNMRQNDIEEVL
>A0A1G9BG14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea maritima|TrEMBL
MRQEAWRSPTSSLAELLRRISYEVVPLRRTEQDVLEHVPVTVPLTVTVTEARGLDPTLDL
AGRLAGHGYAVAPHLPARQFLDQAHVGDVVARLREAGVRSVFVIGGDAPRPAGRFADAYA
LLRAMEDARHPFDQVGIAGYPEGHPSVTKQALGLALKQKAPLATHVITQICFDAGVTAGW
AAGLAAAGVGLPVHAGIPGPVNRQKLVRVTAGIGLGQSARFLRKQQSLLWRLLVPGGYDP
TALARRLGVAARRTGGNVRGLHVFTFGELSGTERWRRRLLAALATQDAQDGSEREETA
>A0A2S8IIS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cepacia|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLEMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDREAIRAFGADV
VTDLCRRLIDAGVPGLHFYTLNAATATRTICERLAV
>A0A1G9M6I5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea maritima|TrEMBL
MLAAGGRSFSFEFFPPKTDEGERQLWRAIRELESLRPTFVSVTYGAGGSTRDRTVDIVER
IAHDTTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVRGDPPGDPMGEWVPHPEGV
LYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIEADTEYFVRKCEAGADYAITQMFFQAD
DYLRLRDRVAARGCDTPIIPCIMPVTQMSTIARSEQLSGAPFPPDVAARFEGVRHDPAAV
RRLGIDHGVEMCQRLLDEGAPGIHFITFNRSSASREVFQRLDRVSLPV
>D0CC63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain ATCC 19606 / DSM 30007 / JCM 6841 / CCUG 19606 / CIP 70.34 / NBRC 109757 / NCIMB 12457 / NCTC 12156 / 81)|TrEMBL
MFRCLQGFDMTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRER
TLAAIEDFNGKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGE
LPYAQDLVRFIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFF
NPDSYFYFIERLDKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDS
ESIKAFGHEVVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A5J6SYA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidiforma bonchosmolovskayae|TrEMBL
MRFLERLAAGRFAVALEITPPQRHLPKVLLRRARLLGDAADAVNVIQRPDRQSSLAASLE
LRAAGIDPVWHLAARGMTAADVTRAAEAARAGGIEQVLCVAGDQAPGEGGAWVTVREAVR
LVRAAMPGVTVGATLNQYARDPERARRNLLPKLAAGASYVQTQPTFDVAALEAELAAVRA
EADGIAAVAMAMPLLTAEAGERIAQRLGLELPGRLRDILAAGDTPGAWAYFRETVARLVD
SPAVQGVAIMTFEMDPPPEMGERIVAALEAAGAR
>A0A1F5LKB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium arizonense|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPIEKVDQALQAAYKAGCTNILALRGDPPRDKEV
WEAADNGFRYAKDLVRYIREKYGNHFDIGVGGYPEGADDNADVEQLIDHLKEKVDAGSTF
VVTQMFYDVKNFIDWVKRCRAKGINVPIIPGIMPIQTYAAFIRRSNWTKIRVPPEWMEAL
EPVKNDDSAVREIGKSLIAEMCRQLMATGINHLHFYTMNLAQATKAVLDELGLCPSDESP
IQRALPWRPSLALNRRGEDVRPVFWRNRNSSYVARTQTWDEFPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSIKDLSDIFVSFLKGKLDRLPWSDSPITTEAKDIQDNLLD
LNERGFLTINSQPAVDGIKSSHSVYGWGPKNGFVYQKAYLELLVPSYLIDELITRIEKND
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCYNAASPSRKLIQNVMEDWYLVNIVDNDFHRSNAVFELFNDLEVKDLNVEVEVPAKPET
NGTAEPNGVATN
>A0A0N0XTL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces chattanoogensis|TrEMBL
MALGTASTRTDRARTVRELLASGKKSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNVIGQYADAGIRNMLALR
GDPPGDPMGEWVRHPQGLDYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDRAAVRSIGIEYATELCARLMAEDIPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A2K6F9Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propithecus coquereli|TrEMBL
LDHRKAKILPAVHHCPSLGMRASEVGSVRLSVPPSISRNPAMVNEARGSGCLNPRSEGSS
SGSENSKDSSRCSTPGLDPERHEKLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQEEITG
HLHKAKQLGLKNILALRGDPTGDRWKEEEGGFNYAVDLVKHIRNEFGDYFDICVAGYPKG
HPEAESFEADLKHLREKVCAGADFIITQLFFETDTFLRFVKACADMGVTCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQKIKDVIESIKDNDAAIRNYGIELAVNLCQELLASGLVPGLHF
YTLNREMATTEVLKRLGLWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVHYLS
GEPNQNGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETAEALLHVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYDEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDAIELLNRPTQSEREAEAP
>A0A3N5UQ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPGFTPGRRWQPAYSPFKRDKFGGRLLEVFEYSVKSPLFGCRMCGNCLLQETAFICPMEC
PKGLRNGPCGGSTPEHCYVDKTRPCMWYKIYERSFRMGREDCLLEVLPPLDWEKVGTDTW
RDVLKQVTKIGVKKVAGGLLSRSAESRHETWDGIFRPIRQPDWWQGDSQYHAPVRTEPAS
ELERRLVAGEFVVTSEITPPLTTKTDKLIHNIQATKNYVSAINFTDNASATPRMTSWACG
QIAVAHGAEPVLQISARNRSRSNFQSEVIGANALGIRNILCISGDSARLSPPPREKMEIN
DLDAVQMLWILRRMRDEGKYLDGREIKFPPKLFLGAAASPFASSPKFQALREQKKVNAGA
QFFQTNLVFDINGMEIWLNELAKRNVLNKVYILIGITPIKSLKMALMLRDVPGVYVPESL
VQRMNAATAAGNVLEEGVQIALELISKIKAYHGQGIHGIHLMPVAWDEIVPRIVTEAGLT
PKDFEFDHTSQEQNNAHHLEK
>A0A7J9Y7P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonosporaceae bacterium|TrEMBL
MAIGAASRLPGQSPSIGDLVRSDGPTFSFEFFPPKTADGELLLWQAIRELEPLQPSFVSV
TYGAGGSTRDKTVEVTERIATETTLLPMGHFTAVNHSVAELRHMIGRYAGAGVRNILALR
GDPPDDPLGEWQPHPDGYSYAYQLVKLIKESGDFCVGVAAFPEKHSRSPDLETDVRHFVA
KCRAGADFAITQFFFHWQDWARLRDAAAAHGCDVPVVPGVMPVTNVRQIQRFAQLSGTEF
PRDLAERLLAVADDVEAVRAIGVEVATELSAKLLAEGAPGIHFYTLNRSTATREVWQNLK
VSAEAGPAARGGGRLTAAG
>A0A7C4QUQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MRLIGDIYAARRAAGKPVISFELFPPKTDEGEKNLLTRTLPELLALRPDYCSVTYGAGGG
TRDKTLKIVETLQREHGLTTLAHLTCVNSTREQIAEVLAQWRSVGVRNILALRGDPTGNA
GPFVAVDGGFEYAWQLVKFIRQQGDFGVGVAGFPEGHLACAAGKQADWDYLTAKIECGAD
FVITQLFFDNRDFFEFRDYLRGKGVRVPLVPGIIPILSAAQIEKFIALCGAQLPADLKRD
LDRLRSDDQAAAQYGIDYATRQCRELLREGAPGIHFYTLNKAASTRAVLQNLGLA
>A0A6L7YLK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTLHTLLQSEKFVITTELNPPKGTELASLLERAESLRGVVDAFNLTDSHTARMSMSPIAA
AHLLLDRGFEPIMQITCRDRNRIALQADVLAAAALGIHNIVTMTGDHPGGGDHPDAKPVF
DIDSTALLRSLTGLQDGSDMSGAELRGAPDLFVGAVVNPGADDLDREIGRMEEKIEAGAA
FFQSQAVYDPAEFERFMRRVEGYGVPILAGCIMLKSGNMARNFNANVPGINVPDSIISRM
DAATSSVNARRRASAEITAKIINDIRPMCQGAHIMAIGWESLIPEVVQFIS
>A0A1G1C8N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium RIFOXYB12_FULL_65_16|TrEMBL
MSKERGTKQLEMRFEGDNPLANCLREGKFVVLLEVNSPPGDQPFDSAVAMASNMAKRIAK
VPEITGMAVTDRLGGEGDHDPVETGARLAAASGKMPLLYVSGKGSDETRVRDLLARAASS
GIRTVVAVTGDRSDRHDAPANAKRVPPYPAGYLDSVDILRFGRKSGQNVLLGAGVNPFKY
SPSDQYLQFYKMVRKLQSGADFLVTHAGWDMRKLQELQWYLQMRDIGHPVLARLRLLMLD
DIQALQDEVYPGVPVAKGFAALLQRESNINATQSLAAQLHRLELQIAGCRLLGYSGVQIA
GIRDVQTLDMVLAKVSEALAATRTYADWVKAWNEFHNAIPFDPVRDAYYVFSRLLQPEPQ
MYDPATAKLTDRSLPGTTKGDRFRARLLPMLLSERMPEWVVSATRRVACCGWQKPLSLLK
YCYHLCPLACPKNLVYGACGGAQPDGTCEFGHAPCFFHRVIALAAQRHELDRLEEGVPHD
>A0A6L8E5M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSSRAHPFLAALDRGIVLADGATDTALRVAGWRGRNDTAVLERPDLARALHEAYIAAGAR
LILTNTFAANRARLALSGLGARVRDANVAAARLARDAREIAGADVFVGGSVGPIGRDLLV
GTWSLRDAERAFEEQVGALVEGGVDVLVLESMPSLEEAEAALRAAQRVTSDHPTIVTLDF
NADACSPAGEEPEEIARRLDAAGSDVIGVNCGVGPQAALDMLQAMAGIRPRARLAVQPNA
GLPRVADGRIIYPSSPEYFADFALRARDLGAAVVGGCCGTTDEHVRAMRAALDRAAAGVE
RSAHARFAGTPQRDPPALDEPDAPGGARGSLRAALAQRRFVIAVEIDPPRGVNPRKALEG
AAALAAAGADAINIGDSPMARVRMSALSLAVQIEREVGIETIIHQTTRDRNLMALQSDML
GAHALGIRTVLALTGDPPPEASRSSPVWDVDSVGFIRVLRRLNEGIDFAGNSIGRPTDFL
IAAAANPTAEDVDRELSRVRAKVEAGAHLLMTQPVYEARTLVRFFERLDADELPVLAGVL
PLMSSRHAEFIHNELAGVDVPPAVRKRMRDAGEGGAEAGLALAREHVDELRDVPWLSGMY
VMPSFGRYEVAAELVRETAAVRERAGSGR
>A0A3M1E9V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVQPFLERLQQGPILCDGAMGTQLYARGIPFEHCFDELNLRNPGIVRGIHLDYIRAGAEI
IETNTFGANRIRLAKHDLEDKVREINRRGAEIARECAGRSDQPVYVAGSVGPLGKPLMPY
GSISTQSAYEAFREQIEGLIEGGVDLLILETFPDLREMEQAVAAAKAVAEVPIIAQMTFG
EDGTTIRGDEPAGIVARLEELGVDIIGANCSVGSQPMLAVVEQMAAVSSTPLSAQPNAGF
PAYIEGRFVYLSSPEYMAGYAKRMVEAGAVIVGGCCGTTPEHIARMRDAIQDLRPPELRR
TTVTITFPEPPPLVAAPLREPTTLARKLGHEFVVTVEIDPPKGFNLGKVIPKLTELKESG
VVDAVNIADSPRAQARMSAAAMATLVQNQLGMETILHVTCRHRNLVALHSELLGAHAMGV
RNIFIVMGDPPRIGDYPDATAVSDIVPSGLIRLVKGFNQGVDMTGKPIEEPTSFFVGAAF
DPGAENLDRELRVLDKKIDSGADFLLTQPVYDPEVIERVLRRIGEFPVPVIMGVLPLYNH
RHADFLHHEVPGISIPDHVRQRLKEAGDDGLDMGIQLTHELLKAVRDYIHGAYVMPPFGR
YDVVAEVARAVVTPMTLREM
>S4YUY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychrobacter sp. G|TrEMBL
MTKPAFSFEFFPAKTEQGHEKLLSTYDELNKLSPAYFSVTYGAGGSTRSRTLDIVQALCA
RGETDIAPHMSCIGDDKSEIAELLEHYKSLGIKRLVALRGDLPSGQVGMGELPFALDLVK
FIREHSGDHFHIEVAAYPEMHPQARSFKLDVDNLVNKYQAGANASITQFFYNADSYLYLR
ESLEKRGIDTVAQPLVAGIMPITNSSNLMRFADSCGADIPRYVRKQLADFGDDSKAIREF
GFEVVYRLCERLISEGVPAMHFYSMNKVEPNKRLIEALGLIA
>A0A6N9GP47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPSDEDSLVRQSGIIARLSDGFKVAIEIETSRGLAMEEGARHSVDLAKAASQGGRVDAVC
FTDNPGGNPHITPETLGRELLDGDAEVVINLSCKDYNRNALEGRLWSLSSLGFRNILCLS
GDYPVDGFSGQAQPVFDTDSVGLLELIRRMNEGLRVTLPGRRNAETELGHTAFHPGAAVN
PFKLYEGEYLTQLYKMDFKLRTGAKWLVSQIGYDARKHHELIRYLNLKHGEEAPPILGSI
FVLSAPAARFFGRWGIPGVAVNSELVEVANRAAKSKDRGRAFFNEFAAKQIAVLRGTGYS
GVYLSGRLTYKRIEQILDIAESITGDGWKDAAAEIGYSQPDEFYLFEPGDSTNTASDELN
REYDARRGRPASFVRRALHPDFAYRIGRFGKHAIFDHDAPAFNASAAIYRQIDKSKIATK
VAHAAEQMMKVPLYGCRDCGDCSLPEIAELCPESQCVKNQRNGPCGGTRAGKCEILDKDC
IYLRAYNTLKLYGEEEDMLNHPVTFTDASLKGTASWANTFLKRDHYAKE
>A0A2E7Z314|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPLVKSAFLNSLGAGTALADGGIGSLIFQLTGRLASADFVYEALNLRNAELIQGIYSSSL
AAGATVLTTNTFAANSTELAAAGVGDQVAEINNAAVNIARDAISGHIVEYSIDNTEFFVI
GSIGPGGSDVDAYSSQIDALIAGSIDALLLETFSDIDLAMGLTKAITSRPDSPPVIVHGA
LDPSVGDYLEWPIDPATFVDQAASAGASVAGINCVAPWVATEFVLAASASSAVLAGELLL
SAMPNAGGFERIGHRFLTRANPEYMGTLARQLSDSGASLVGGCCEVHPEHVREMSAYLKL
RTSSMGLAEHTKNVSRVAKTRPPNDPRRLNGEFSRKIIEGEFAISIELVAPNGSDSKALD
LRASFVQQIVDEGLADAVDITDGSRGIPLVPPGDLVELIRNRLNWRYGDQLEFIAHFAAR
DLNTLAVQSRLMGYHLRGIRNVLFVTGDPPKMSPTYPRSTAVFDMNSVQMIRATADQLNT
GRDFGGNPLGGELDSSTRFTIGSGFEPEAINMILETDRLRSKIDAGADYIMTQPVFDSTS
ISVLEPFRDLIAVLPGVMVIRSTAHAERIAQVPGVNLPQTVIDRFSKYESTVDQAKVGLE
LAVTQSSQYREQEWPGIYLMSPASLGAAATVLKTLAE
>A0A3M1Y9T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRSWECKMAKLPLRDRLKQATPLLADGAMGTLLHQRGAAINACFDALNLTSPEIVKQIHL
DYIHAGSRLIETNTFGANRYKLEEYGLSGKVVEINQTAVQIAKDAIASSGVNEDIYIAGS
VGPIRVGMRPYGRLNKSDVRTAYVEQIRALIHAGVDCILLETFTDHQEIFIALDVIKAIR
LNDDLDIPVIAQMTFSDDNRTPLGYTPARVAHELQRAGADVIGVNCGIGPNQVATVLQAM
HQTLPGLRFSAMPNAGFPQTSGGRVMYPASADYFGDYALTFKAIGASIIGGCCGTTPQHI
AAMRAALNDASRQVPNIQIIETNGDDVEAVPDHPTMLAERLADGKFTITVEIAPPRSFDV
EKLVRSAKMLRDAGADILDVADTPAARMRMSPWAVAHVIHSQVGVETVLHFPTRGRNLLR
IQGDLLAAHALDLRNLFVTMGDPTKIGDYPDANDQYDIVPSKLIELIKHKMNYGEDMGGN
SIGRPTAFTVGCALNMFANDLDKEIKVLNNKLAAGADFALGQAVFEPHRIETFIRRYEEI
NARPFELPVLMGIMPLFSLRHALFLHHEVPGISIPDHIMKRMEDAGDDAPAEGVRIAQEL
LRAVRGMVAGAYIIPAFGKYELAAEVLDAVAVPG
>A0A6L7TTV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLQEGRTISFEFFPPRNADGIPGVLDTVNELTSYCPDFISVTYGAGGSTRHFTEQITIEA
KQSAGVEVMAHLTCVGQTVDELDTVLQRLDDAGIENVIALRGDPPRGEEYFTATEGGFSH
ASDLVTHIHANYEFGIAAACYPEGHTEAESLERDLQYAKLKVDKGADFLITQLFFDNADY
FAFADRAVASGIDVPVIPGILPVLSAPQIRRFTALCGSKIPTDLDAELDRLADDDAVRDL
GVEYAARQVEELWAAGVPGVHFYVLNRSYSVSKILDHLAIPGHIPD
>A0A535IZZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQHDFLEQLQQHPLLCDGAMGTLLYARGIAYERCFDELNLTRPALIQGIHSEYISAGAQI
IETNTFGANRAKLEAYNLEGRVRDINRHAVKLAREAREISGQSVFIAGAVGPSGRPLQAP
DEQRLSELRAIFREQIDALLVGGADLLILETFSSLAELRQAVLAAQDVGGLPIVAQMSFY
EDGHTLSGQSPARVAAVLNDLGIDVMGANCSVGPAATLDVLQEMIAAARLFLDNEQAIPQ
MFSAQPNAGLPTRIGNRFFYMATPDYFADYAVRFARAGVQLIGGCCGTTPHHIAAMRKAL
NDAYGAATPSIPGSSRETLQAKPVEITNGKVTIAGLIEEEVILPQQGTKTRLQEKLAARE
FVVSVELDPPKGLNPAKILEGAAMLQKVGVDFINIADSPMARVRMGCIALARLIQDHLGI
ETIIHFTTRDRNLMALQSELLGAHALSIRNILSLTGDPLHVGDYPNTTGVWDLDSVGLIQ
VLRRMNEGHDAAGSSIGAQASFHIGMALNLNMTEQETEQEIDKYRRKIEAGAHFIMTQPI
YELARLECFLARVGKPPIPMLLGCIPLHSSRHAEFLHNEVPGITIPDDVRSRMRAAGDQG
HEEGLKLAQELLTSARSMIQGVYLMPSYGRYDVVSKLTKMLQMQPTP
>A0A3M1XDS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSRSNFLERLAERPLLADGAMGTMLYARGFGFDECYDALNLKHPEVIVDIHRQYAAAGAD
ILETNTFGANAFRLAAWNLESSAAELNMRGVELARQAARDVRADILIAGAVGPLGVHLAP
LGNISREEAYRAFYEQIGALAEAGADLLILETFSDLAELEEALRAAKAACNLPVVAQMTF
NREQRTFMGVTPLQAVQVLTPWRPALIGANCSTGPQGVLEVVRHMAAAAKAVPGAPGLSA
MPNAGFPEVRGSRVFYPATPEYFAEYTKQFIEAGARLVGGCCGTTPAHVRAMRAAFDKLT
ASASTAVAIARVEIHHSAEGGHAHPHGDARIPTTLAQALAERRFVTTVEVEPPKSADTSA
IEETARMLKEAGATVLDISDIPMARMRMTGMAAAYRVQAGAEIETVLHFPVRGRNLLRVQ
GDLLAAHALGIRNIFVTMGDPTRIGDYPQANDHHDVVPTGLVQMIKAQFNVGLDGLGASI
GKPCAFFVGVAANLTPTDFEKEAKLLRKKIECGADFALTQPVFDAEMARRFIAYYEQMFG
KLTLPILAGILPLASVRHAQFLRNEVPGVMMPEAIVRRLEAAGNKTRTEGAIIAMEILAG
IRDLVQGAYFIPAFGRYDIVAKLIQQTTGQLQLSSS
>A0A828T2B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium 1_1_57FAA|TrEMBL
MKIIDRLKEDKIHISFEVFPPKTDAGFEKVIAATDAMAKLNPAFISVTYGAGGGTSKNTA
KIASHIKDDLGVVSLAHLTCASSTIEEVRDVIENLKENGIENILALRGDIPEGMPFPNGN
RFRYAYELIEEIRKHGDFCIGAACYPEGHVENEHKAEDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGINVPVLPGIMPMTSEKQMKRSQELSGTVFPRRFLALLDRFGSSAA
AMEQAGIAYATDQIIDLLSNGVNNIHIYTMNKPHVAAAIMNNLSEIIKA
>A0A7C6XW97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSEHPFVTRLAQGPLLADGAMGTELYNRGIALGQCFEAANLHQADMVQRIHLDYLAAGAE
LIETNSFAANRYGLAIHGLADELRAINRQAGRLARYARDMAGSLAFIAGAMGPLAHPLAP
LGPITEKDSLDAFREQAEALLEGGIDLFVLETFGDLNELCLAIQAVQSISDLPIIAQATF
DQDGRTPRGQDAIKVASTLLDTDIAVIGVNCSAGPQMVLEVACTMASVGARYVSAMPNAG
LPTRSNGRLIYLTTPEYFAAAVPQALAGSITLIGGCCGTTPAHIAAMRKALDATGGKEVA
EAPCRVAVVPRDTREKDVAEPTPFAQKLARGEFVTSVELTPPRGFRTGALLRSARELAEC
GRVDVVNVTDSPMARVRMDAVAACYLIQSQTGVETMLHLTTRDRSLMGLESALIGAHAMG
VRNILALTGDPPSLGHFTQSTGVFDVDSIGLVRVIQEMKQGRDLVGTEMGHPGGFCVGVA
VDPTKPDLDAEARRLKEKIAAGAEFVMTQPIFDLALWQRFLEVYDDEIGVPVLLGVLPLL
SDRHAEFLHNEVPGITLTEAALERMRRAGAEGRNEGIRLAQETILEAREQFQGVYLIPSY
NRCEMALAVLETLETVR
>A0A536KK58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTTPSRLAGLLGEGRFVVTAELSSSNSADPEATWRRAEVLRGSVDAINCTDNTGAHVHMS
SLAAAHLLVEKGLEPIMQLTVRDRNRLALQADLLGAAALGVRNLVLMSGDDVTAGDHPEA
RRIYDIDSMQLLEVASAMRDRGTYLSGRKLEQAPSFFIGAVENPFAPPLDFRPLRLQKKV
RAGAEFIQTQLVFDVPIFKRFMDMVGELDLQRKVFIIPSIGIPRSARGARFMQQKVPGLH
VPESLVSRLERTAPARQAEEGIQIAVELVRAVREIPGIAGVHLIGIKWEEGVVQVAERAG
LLPRPTLSPLASVGGRG
>A0A2E5DHD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIIDLIKKKKTISFEFFPPKRESDLPKLYETVDRLSTYNPDFVSFTYGAGGNTRQLTIK
VSKDTKIANLTQVMTHLTCVAHTKKEIDTILDELSKYKIENIIALRGDKPKDIDIKNELI
HATDLISYIKNQSNSFCIAAACYPELHPETNDFSEEIKYTKLKQDKGADFLVTQLFFDNK
DYFKFVDESLXKGITIPIIXGILPIVSTSQIRRXTKXXGSKIPNXLNIKLEKYKDNXLET
AKLGIEYATKQVLELIENDVPGIHFYSLNKTKSVGHVLXNLGISTQTPEHII
>A0A428SV60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium ambrosium|TrEMBL
MDRITDRIAALPADGSYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRREE
YRDPDDSEDDGGQDFNWAADLVKYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVEAGADFIMTQLFFDIKAYEHFENTLRDHPSGAFKTLPIIPGLMPIQSYQMIKRT
TKLSHAQIPEDILARLNAVKGDDEKVKMVGVDIVSELVEKVKDIKNKTPGPKGFHFYTLN
LEKAVSFILERTNLIPEPPEDEEALVVDDAIPIPALQVNGSSNLRSGSHSRSRASRRHSS
VGSDPHNRVIVGDRPATHPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDF
PNGRFGDARSPAYGEIDGYGVSLHMSITQAVKFWGHPKTRQDINDLFVKHIQGELSAIPW
SEEELLAESSTIQPHLLRLNQKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEF
FIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVSSDKGGHVDGSSEAGPSTNAVTWGV
FPGKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSDSEKLLSGIKDEYWLVNLIHH
DFVEKDALWQVLSS
>A0A2D8LDY0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIIDILNSKKTISFEFFPPKRDSDLPKLHETVDRLSTFNPDFVSFTYGAGGNTRQLTTQ
VSKEAKLSDKFEVMSHLTCIAHNKAEIINILKDLTLSNIENIIALRGDTPKDITISKNNL
KHATDLIEIIKSNFSNFCIAGACYPEFHPESNNPVDDIKFTKMKQDKGVDFLITQLFFDN
KDFLSFREKAIKLGITIPIIPGILPITSTKQIRRFTKLCGAKIPLKLNEKLENSINDDQE
TTKLGIEYATNQILELIDNDIPGIHFYSLNKTSSVGHVLNNLGISNQTPEYII
>J8Q880|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces arboricola (strain H-6 / AS 2.3317 / CBS 10644)|TrEMBL
MKITEKLEQQRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGG
RLSHLSTDLVSTAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRD
AESWTQVEGGFKYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPSKDSKLDLEYLKQKID
AGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYGAFLRRAQWGQIRIPQE
FLAQLEPIKDDDELVRDVGTNLIVQMCQKLLDSGYISHLHIYTMNLEKAPLMILERLNIL
PTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGD
SSSPAFGDLDLCGSDLIRQSANKCLELWSTPTSINDIAFLVINYLNGNLKCLPWSDVPIN
DEINPIKSHLVELNQHSVITINSQPQVNGIRSNDSIHGWGPKDGYVYQKQYLEFMLPKTK
LSKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL
AWKEEFYHILDEWKLNMDKYDKPQSSQFIQSLIDDYCLVNIVDNDYISPEDQIHSILLNL
>A0A258CT94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter vibrioides|TrEMBL
PLDPAFVSVTYGAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRDEVNEVIREYWET
GVHHIVSLRGDPPPGEGGIGGVYVPRADGYANATELTKAVRAIAPFEVLVGVYPEKHPES
PSLEHDIDVLKQKVDAGATLGISQFFFDLDAFLRFVDKVRAAGITIPIVPGIMPVTNFAG
LKKMAAACQTAIPAWLGNLFDGLEHDAETRRLIACSVAAEMCAKLQEQGFEDFHFYTLNR
ADLVYAICRVLGVREVSPAASEAAA
>A0A3N5SXI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPLFTPGRRWQPPFSPFKHEPFGRRMLARVERMVKGPLFGCRMCGNCMLQETAFICPMEC
SKGARNGPCGGSTQEFCYVDQTRPCIWYRIYERSFAMGREHKLLEVLPPLDWDRVGTETW
GDVWHQARKVGMKKFVGGMFSRDVTARAANWDSVFRPIRQPDWWQGDSEYHAPTYQEPMS
ELERRLKAGQFVVTAEVAPPMSTATGQMTRNIQLVKPYVAAINFTDNPSATARMSSMACS
ILAMQNGAEPVMQIAAREKTRTSLQSEVIGASALGIRNVLCLSGDSGRMGPAPMGRLDTL
DLDSIQMLWILRRMRDEGHY
>A0A535JDK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
VPREVTITVTASPRRGVDATIELAERLARNGYGVVPHISARLIRDSAHLREVLERVAAIG
RNEIFVVAGDAKEAAGAFPDSVSLLTALMSEPHGLREIGVTGYPERHSFIDDDLTIQAMW
DKRSIATYIVSNLCFDPRTVRKWVARVRRRGVQLPIYIGLAGVADPAKLLRISTRIGVVD
SARFLRGHSNWFLRMIRPGGYDPGRFTAGLLPDLASPERKVAGLHVFTFNEIEPTERWRQ
ATLARLLAA
>A0A2D9A4H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSSSTSSGTGISSGFPSVNLSNSSESIWPNCLPSICRLFSPIHTGGAPVVKITESCFEAT
GHTSVICDFSPPRSGDQXVVDQAQIGADFISVAYNPGRAVRTNSAMLAAAIQNSGNDAVF
TLATRDMNKLALQSQLLGAQLLSVQNVVVVQGDPFGEHDQKRVASVNDYSSTGLIAAIAD
MNQGQDFKXSKLGQPTDFCIGAAVDLGRGIEEEAXLAVRKVQAGAEFLITQPIFNVDHVA
RYRESFGYHAGKAGTVPIYFGLQILENDGVLFSSVPESLRAELEAGRTGVDIALELYGKF
QEGRLNNIYLMPPIKRGGARDYEAAKEFLGXIKRI
>A0A535UYS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLARSKPTVSFEFMAPRDESEVDALERTVATLAGHAPDWVSVTYRLRTGDKTLEL
VTRIKRHYHIEAMAHLTCANTADRTRQILNWMEREGVANVLALRGDSPASGEPFTPADPQ
LTHASDLIGLVRRSGYRFGIGAACSAEKHPESPDVEHEFRYMRYKVETGADFLITQLFFD
NRFYLDLVARARAAGITAPIVPGLMPIPSRRSLGVMTAMSGATVPAAPRPSRSSPPSGAS
S
>A0A536CJD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLVGGRPTVSFEFMAPRDESEVDALEKTIAALAGHAPDWVSVTYRKATGDKTLEL
VTRIKRQYHIEAMAHLTCANTADETRRILNWMEREGVANVLALRGDPPGPGAPFQPTDPQ
LMHGSDLVSLIRGSGYRFGIGAACSAEKHPESPDLDHELRYMQLKVESGADFLITQLFFD
NRFYFDLVRRASESGVELPIVPGLMPVPSRRSLAFMTSMAGATVPAGLESEIAAAADDEA
VRAAGVRHCIAQCVELLEAGVPGLHFYTFNRARAPMEILAALRGQQLLTA
>A0A5H2YFV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. SG09|TrEMBL
MERNLWETINRLAPLDPKFVSVTYGAGGSTRERTHSTIARILKETALLPAAHLTCVGASR
GEIDEIVDRYHEVGVRHIVGLRGDPAGGIGTPYASHPDGYQSSAELVAGIKKRHADIEVS
VSAYPEKHPEARDFDDDIDTLQAKVDAGATRAITQVFFDNDLYFRYLDRVRARGIDIPIV
PGIMPMHNFKQARNFVTRAGTTVPDWFAAKFEGLDEDAETRKLVAATVAAGQVQKLAKHG
VDTFHFYTMNRADLVFAISHLLGIRAKSAQKAA
>A0A3C0UCN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusaceae bacterium|TrEMBL
MSTLQTKLANGQFTLTVELDPPKSADASKTISEAQQLKSRIDAVNIADCPMANLRMSPIA
LSHVIQADVGLETIFHLTCRDRNIIGLQAELLGAAALGVHNILALTGDYPQQGDHPQAKA
VFETDSTGLIELSAKLNNGRDTMGNELGKGTSFFIGTAVNPGADDLDKELEKLSAKIAAG
ARFVQTQPVYDLEIAKRFMEKVKDLPIYVLMGILPLKSHKMALYLHEKVPGITIPQTIMD
RMAAGGKAAGLEIAAELVRGTKNIAHGVHIMPLNDIQTVVALTDQL
>E0J6A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / LMG 11080 / NBRC 13500 / NCIMB 8666 / NRRL B-766 / W)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A535UIU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTRQGLIAFLQAPRYEVLPTEEVEELVLVHVPKDITVTITASPRRGIEATIALAERLAAQ
GYQVVPHLSARLIRDHAQLSEILARVNALGRSEVFVIAGDAKEPAGDFGDSVSLLAAIDA
EPHGLLQIGVTGYPERHSFIEDDLTIQAMWDKRRIATYIVSNLCFDPRIVKKWVGRVRRR
GVELPIHIGLAGVTDPSKLLRVSTRIGIADSARFLRGHSNWFMRMVQPGGYDPERFAAGL
LPDLAAPDRRVAGLHFFTFNEIEATERWRQETLARLLAA
>A0A350ZPQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp|TrEMBL
MIRTLTEADKTRDPLRVSFEFFPPKSEAMATRLWDTIKRLEPMAPDFVSVTYGAGGSTRE
R
>A0A536MA25|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSPSRLAGLLRDGHFVVTAELSSSNSADPQATWRRAEVLRGSVDAINCTDNTGAHVHMS
SLAAAHLLVEKGLEPIMQLTVRDRNRLALQADLLGAAALGVRNLVLMSGDDVTAGDHPEA
RRIYDIDSMQLLEVAAAMRDRGTYLSGRKLEQAPSFFIGAVENPFAPPLEFRPLRLQKKV
RAGADFIQTQLVFDVPVFTRFMDMVGELELQKKVFIIPSIGIPRSARGARFMQQKVPGLH
VPESLVNRLERTAPARQAEEGIQIAVELVRAVREIPGIAGVHLIGIKWEEGVVQVAERAG
LLPRPTLSPLAAIGIVPSPARGGGQGGGVP
>A0A536GWT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVSGRARSVPGASAKLLGRIGLTDETSRQGLIDFLRAPRYEVLPTEDVEDLVLAHVPHEV
TVTITASPRRGIEATMSLAERLAGHGYQVVPHISARLIKDEAHLQEVLERVAALGRKEAF
IVAGDAKEPAGEFPDSVSLLAAITAHPHGLREIGITGYPERHSFIEDDLTIQAMWDKRRI
ATYIVSNLCFDPRIVKKWVARVRRRGVQLPIHIGLAGVAEPAKLLRVSTRIGLADSARFL
RGHSNWFMRMVQPGGYDPERFATALLPELAAPDRNVAGLHFFTFNEIEATERWRRETLAR
LLAS
>A0A3M1WI48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MHSTLQRRLAAGQIVVTGEIAPPKGAARSHLEALARNIRDYVDAVNLTDNQRGIARMSSL
GGSVILQQLGIEPIMQMTCQHRNRIALQADALSAAALGVRNLLAMTGDHPRIGDHPEAKN
VLDLNSFQLIRVLRTLRDQATFQSGTPLKEAPRFFIGSVANPNVERAARLEKKIEAGAEF
VQTQLIFDVGRFRQWMADVRAAGLHQQAYILAGVMILRRPHSAIYLRDHLPGTLMPETVI
ERMQRATDSEAEGITLAAELVNELLSVEGVAGVHIMSVDWTRAIPRVVEQAGLLPRPPVP
STEENVL
>A0A535JLI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGALASLLRSGEFVVTAELNPPKSAAAGVVRRRAEALRGVVDAVNVTDSNRAVVAMAAIP
AATIIHSVGLEPIVQMTGRDRNRIALQADVLGAAAIGIESFVFMSGDDPADGNHPTAVNV
KDLDGVGLVKMAVAMRDQGRFLSGDEIKQPPKILVGATASPFTKPMEADLAKTIEKIAAG
ADFLQTQPVFDLATFSQWLVAVRRDGSRDVAILAGVLILRSAEQAERLAKVPGVSIDAEV
IDRLKKATDGEAEGVAIAVEMVKALRALPGVRGVHLYAIEWPEAVGRVVEAARLLPRPEA
RVVAV
>A0A081AI86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora parasitica P1976|TrEMBL
MKVIDKINASVERQEVFYSFEFFPPKTPAGVDNLYARMDRMAALEPLFCDMTWGAGGSSA
QLTLELSANAQKLSGLEMLMHMTCTNMAEADIKKALDEAKDAGIQNILALRGDPVRGASS
FDECDRGFSHAVDLVRYIREKYGNHFCIGVAGYPEGHVEIKDKKADIQYLKEKVDAGADF
VITQLFYDVQVFVDFVKECRAVGITVPIIPGIMPIQNYGGFERMTSFCNTFVPDEVRKAL
EPIKDNDEAVKDYGVQLGITMSQQLIDAGVPGLHFYTLNLERSVRRILEGLSSLSSRVPR
RELPWQTSTLSKRASESVRPIYWSNRPKSYVHRTAMWDEYPNGRWGNSESPAFGELTESH
FAPSNTSTPRERRAMWGEAPAAKEDVRRTFVQYVRGEISSLPWCDAALHAETSTVQQELA
AANSAGFLTINSQPRVNGALSDDPMFGWGGPGGRVYQKAYVECFVSPENMKIIIENAAKK
PSIQYHAVNLNGHSYSNASKSAVAVTWGVFPNKEILQPTIVDSSSFLVWKDEAFALWLKL
WASLYEPGSQSAKLLREIHDTYFLVSIVDNDFVNGNIWDLFEASVSPATSP
>A0A2W1APT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKSVLEAINEKGQKPFFICDFSPPKGGNPDLLLESYDLNPDMFMVAYAPGKSVRLNPIFA
ADWIYSKTKIPSIFTVSTRDMNKSAMQSLLLGAELMGLPNVLIVKGDKLTAEDMYLQTEV
NDFIPTELVSAVKRMNERRDFRGNELTYPTRFCIGAALDLSRDWEKESHLTKLKITRGCN
FIVSQPTFDPELPSKFLSFYENTIGEKLKIPVIWGIQMVEKDTISFANVPRWVHQNLEEG
GSSYEITIDLVKRYLELGIGTFYLIPTIFKGGRRDYLSAQAVIEDIE
>A0A2E6UGA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MHDLIEAYRKSNKPLLLCDYSPPRSPGAMNLDSLKKLPVDYFSVAYNPGKAPRVDSITAA
RLIQSVTSKPVIFTMAARDMNKIAIQSQLLGASISDLNNVLLVGGDPLAELEKKNGATEV
RDYKPTDLIRSTAQLALGLDYRGMKIAEPPVFCIGAALDTSNNLDLEIPLMLTKIQAGAQ
FFITQPIYEINEYYGFLEKFKSITGSDLTVPIFWGLQVLSSDGPIFGKPTQRVLNNLNYK
INPLRIARALLQDMRSAEVKGIYLIPPISSNGRRDYASLNDVIYA
>A0A536QVX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRISEAFKLGRPVYSFEFFPPKTDQAARDLFRTIDELQVLRPTFVTVTYGAGGSTRERTI
ELATELKHRIRIEVAAHLTCVGHTAPDIARICERLRANGIENVMALRGDPPRGDLAFKQV
EGGFAHATELIRFIKERFDFCVGAAAYPEKHPESISLEDDLRWAGAKIDAGAAFLTTQLF
FEADAYFDLVRKARAAGIRAPILPGIMPVTNIAQIERFTKLCGATIPARLRAQLAAADGD
ERAVVRVGIEWATAQAEALLAGGAPGVHLYTLNRSFATREIFARLRAERPPAVI
>A0A3D2LA87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp|TrEMBL
MSSLVTPRQAGSPSVSFEFFPPKSEAMADRLWETVERLEPMTPNFVSVTYGAGGSTRERT
HDTVRRIAQQTHLRPAGHLTCVSATKDEVLSVAEDYWEAGVRHIVALRGDPPSGMGEKFE
QHPGGFRDSIDLIEGIRAHRPDLGRCFEISVSCYPELHPESQGWDAEIAFLKAKQDAGAD
RAITQFFFEPEIYLNFLEKARAGGVTMPIVPGIMLQPNFKGLKR
>A0A536G9P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLDKVRTMRIADMLARSRPTVSFEFMAPRDESEVDVLERTVATLAGHGPDWVSVTYRVRT
GEKTLELVTRIKRHYHIEAMAHLTCANTADRTRQILNWMEREGVANVLALRGDAPVSGEP
FTPADPQLTHASDLITLVRRSGYRFGIGAACSAEKHPESPDLEHEFRYLHLKVESGADFL
ITQLFFDNKFYFDLVTRVRAAGITLPIVPGLMPIPSRRSLGVMTSMSGASVPAALQSAID
EAPDDEAIRALGVQHCITQCAELLETGVPGLHFYTFNRARAPIQILAALRGQQLLAS
>A0A4U0Z772|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas portus|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
SGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGD
>A0A3L8NXC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marmoricola mangrovicus|TrEMBL
MRNKLAVRRPSRDEVRQGLLRLLAHARYEVLPTATTEQKILDAVAVDRTITVTASPSKGL
EATFDLAERLAGHGYTVVPHVAARMVSGRTELSEICERLTAQGITHVFVPGGDAEAVGDY
PDALALLTDLKELGNPFSHVGITGYPESHPTIHDDLTVQSMWDKRHHATTIVSNLTFDPS
AIASWVGRLRARGVTMPLLLGMPGPVERAKLLSMATKIGVGESTKFLAKNKGLFARLAAP
GGFTGERFLTQCAPALVPAEALVEGLHVFTFNQIAETEAWRSELVARLEA
>A0A2A2WI38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopirellula sp. SM50|TrEMBL
MSSPIKLADHYNGEQCAISFELFPPKTDAGMDLLEKNVERLKAFQPSFFTCTYGAGGSTQ
SRTLDVVQRVRELTGLPVASHLTCVGATVEQLGEYLAEAKRRGADYIVALRGDPPKGSES
FQAVEGGLRYANELVELIQARFPDQFGIAVAGYPEVHQEASDAQTDLDNLKRKVDAGADV
IVTQLFYDNGDFYRFRDACQAAGIDVPIVPGILPVTNYKQALRIAGMCKARIPDQMAAAM
NENDDADYQFKVGVDHARVQTIDLIENGVPGIHYYVLNKSDAAGQMLDGLSLGVQS
>A0A7J7T101|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pipistrellus kuhlii|TrEMBL
MANEPRGNGGPNPRLEGSGGGMESSKDSSRCSSPGLDPERHERLREKMRRRMESGDKWFS
LEFFPPRTAQAAVNLISRFDQMGAGGPLFIDVTWHPAGDPGSDKETSSMTIASTAVNYCG
LETMLHMTCCRQSQEQITGHLHKARRLGLKNILALRGDPVGEQWEEEEGCFRYARDLVKL
IRSEFGDYFDICVAGYPKGHPDAESLEDDLKHLKEKVDAGADFIITQLFFEADTFFHFLK
ACSRMGISCPILPGIFPIQGYHSLRQLVKLSKLEVPQKIRDVIEPIKDNDDAICNYGIDH
AVSLCQELLASGLVPGLHFYTLNRRMATTEVLKRLGMWAEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQDWDEFPNGRWGHSSSPAFGELKDYYLFYLTSKAPREELLRMW
GEELTSEESVFEVFVHYLSGEPNQSGCPVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRDTVGALLQVLKKYEQRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWVEKWGKLYAE
GSPSRMIIQDIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLHRPGTRGDRLRDPVP
>A0A0S6U2S9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum B str. Osaka05|TrEMBL
MHIKELFNQKNLVFSFEIFPPKATSSVKTIYETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTRKDIDSIINELKENNIENILALRGDIPKDKNIIGK
YNYAFELIRKIKENDNFGVAGACYPEGHIECESLEKDIKELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQQKNINVPIQAGIMPVVNKKQIERIIKISGATLPKKFMKILDKYEYDKEA
MRDAGIGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARRITESTKSIFNSINKDIAV
>A0A840JDB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas axonopodis|TrEMBL
MDFGSFPLDQCVVAMPPNHHDKTARPVISTDTPNFASTVTEAYSLEVSAKDIGALTNAAP
RILPGCAMFIPYLPGQNEAVRLAAAQMVRRLGFEPVPHLSARRIGSLGELQACIARLVDE
AGVTRCLVIAGDPSTPKGPFPDSVSLIETGVFERSGIRTIAVAGHPEGHPILRTTEQWDV
LERKCRSIQERGMAPLIVTQFGFDADIVVTWLEALRARGMTHPVRVGVPGPASVAVLARY
AASCGVGACASVLSNYGISIGKLFGNAGPDRFVDRLASRLTKAHGDVRLHLFPFGGIAQS
VEWVAHYRSRASQQDRMRSVRADQA
>A0A7X8WGN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MRVPEIIQAAKKPLFTFELVPPLKGRKLEPLMETIRTLMEFSPSYINVTNHQAEVVYLER
EDGLLQRKTVRKRPGTTALAALIQHTFGVPTVAHLICGGMSRDQIEDVLIELHFLGIENI
LALRGDPPAGEKRFVPMPDGHAHSSQLVEQIVDLNHGRYLDDQYRDGEATRFSVGVAGYP
EKHAEALNMTVDLANLKKKVDAGAQYIVTQMFFDNGKYFSFVNACRSIGITVPIIPGLKP
IASKRDLSLIPQTFGVDLPEALTSELE
>A0A7C1SN60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MSELKAGTNLERVLQAGHFAITAELGPPKSADVDVIKTKAAYLKGIVDAVNITDNQTAIV
RMSSIAAGVLALKEGLEPVIQITCRDRNRIAIQSDVLGAYALGLKNILCLTGDHQVFGNH
STSKNVFDMDSIQLIQALKNMRDEKVFICGDEIKNSKKAPVVEPRIFIGGAANPFGDPFE
FRVIRLAKKVNAGVDFIQTQCIYDMERFEKWMKQVRERGLHKKVKILAGLTPLKSVGMAK
YMRDNVAGLTVPDYYLERLSKVEDKAAEGIKICVEQIKRLREIEGVAGIHLMAIEWERRV
PEIVEAAGLLPRP
>A0A7Y1GEE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. WS 5414|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLQQYQAAGIKRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLTHFVRKANAGADSAITQYFFNADSYFY
FVERVQKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQVISQMCERLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>Q0EWI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mariprofundus ferrooxydans PV-1|TrEMBL
ISPAYISVTYGAGGTTQDRTKGIVTRIKDETGLSPVAHLTCVGASRDELAALLADYRAAG
IENILALRGDAPEGLDRFEAVAGGFSYATDLIAFLREQGDFSIACATYPEGHPESAGGVA
DDIRYLKLKQDNGADAAVTQYFFDNDAFFRFRDACRAAGITLPIIPGIMPIGNYDQIVRF
SSMCGASIPAWLHEQMQPIRDDLEAVKALGIELAAKQCRELLQAGVPGLHFYTLNKSEAT
IAIRNQLTDLL
>A0A414L696|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides intestinalis|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYDTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAGAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELACEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A2D9Q0W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium|TrEMBL
MTTNAPISFEFFPTKTEAGHEKLLATARTLAAAGPEFFSVTYGAGGSTREGTRRTVLQLD
GEVKVPTAPHLSCVGDSREDLRNLINDYRANGIQRIVALRGDLPSGMGHASGELRYANEL
VEFIRAETGDHFTIEVAAYPESHPQAPNFETDLQNFIRKAHAGADSAITQYFFNADCYFH
FVDRVRQAGVDIPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDSISAFG
TEVISQLCERLLDGGAPGLHFYTLNQAEPSLAVVRNLQGDR
>A0A2D9U4C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium|TrEMBL
MNSQQQHEKRFSFEFFPPKTDVGIEKLNLVQQTLAEKKPRFFSVTYGAGGSTRDRTFETV
NNVKNRTGIDAAPHLSCVGDTKAQLAQLLNQYQDAGINRIVTLRGDLPSGMGASLGELKY
ASDLVAFIREQSGDHFHLEVAAYPEMHPQAKSMDADLQAFKTKVRAGANSAITQYFFNVD
AYKFFVDSCEKMGLDLPIYPGIMPIINFDNLIRFSSMCGAEIPRWIRMRMECFRGDEQSI
KQLGEEIVTSLCEELLAMGAPGLHFYTMNQAEPTIAIWDNLNL
>A0A5C4STG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeobacter sp. B1627|TrEMBL
MTTPEISFEFFPPKTLEASFRLWDTVQSLAPLAPRFVSVTYGAGGTTRELTRDAVTTLHK
NSGLKVAAHLTCVSATRQETLAIADQYAEAGITDIVALRGDPPKEQGQFAPSADGFNSSV
ELIEALADKGGFNLRVGAYPESHPDAASPQANVDWLKRKLDAGADEALTQFFFETETFFR
FRDTCAKAGIDTDKITPGILPIENWTGVRRFAQSCGTAIPAWLDEAFDKAARDDRTDLLA
TALCSELCTELLEGGVKRLHFYTLNRPELTRDVCHALGVKSKMRLENVA
>F8Q5A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serpula lacrymans var. lacrymans (strain S7.3)|TrEMBL
MKISKKIDQSTKDGKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGMETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPQGKDE
WEAVEGGFVHGIDLVRHIHNEYGDYFDIAVAGFPQNQLLPPEERDLEMKYLKEKVDEGVD
FIFTQMFYDVEVFIDWVKAVRVAGITIPIVPGIAPIQTWNGFMRATSLAKTQIPQSFMEA
LEPHKNDDEKVREIGTKLVAEMCLRILKEDIGIRGLHFYTMNLEKGTKMLLEELNLVPRV
ETIKPLPWRQSLTPNRRQENIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDAMKLWGQPTTFNEITTLFSRFCSKELSALPWSDQKASKETSAIAPQLS
KMNELGFLTINSQPAVNGAKSDDKLFGWGPSNGYVYQKAYLEFFVGPELLNLLLTHIERD
SNITYYVINKQGDLRTNTHSEGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAYELGVQ
WANFYDAGSPSHQLISEIMETSFLVNVVHNDFTLPNAIFEPFFKAGEEYAAAHPNGSTTA
KGIPN
>A0A084JFS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacrimispora celerecrescens|TrEMBL
MKLSNILKNQATLSFEVFPPKRDGSIQTIYNTLNALQELNPDFISVTYGAGGNGNGHATC
EIASTIKNQYKIESLAHLTCAGLSKEDLLSQLDIFKQNGIENILALRGDILDPKQSKGDF
TYASDMIAFIKEHGDFDITAACYPEGHNESKNLIEDIRNLKKKVDSGADQLITQLFFHND
YLYRFQERCSLAGIHVPIEAGIMPVINKKQIERMVSLCHVELPSKFITMMNRYENNPVAM
RDAGIAYAIDQIVDLVVHGVNGIHLYTMNNPYIAKKIHEAVYRLIKE
>A0A1I3D9T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides psychrotolerans|TrEMBL
MAELIGEGRRSFSFEFFPPRDEAGEAQLWQAISELEPYEPTFVSVTYGAGGSNRDSTIRI
TSRIARETSMTPMAHLTCVGHTREELDQILHSYVDAGVHHVMALRGDPQEGPRAAWTSTP
GGLDYATELVEMAHTRGDFRIGVAAFPEGHPSAESLDHDADVLVAKAQAGAEFAVTQMFF
RASDYVGLVERVRARGVDMPILPGIMPILNLNAIRRQGELIGTDVPAEVVARISVHDGDP
VAMRAEGIAIAAELCEELLEAGAPGLHFYTLNRSKATREIFQALKITV
>R5K0V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:264|TrEMBL
MKIRDIIGQEKATLSFEVFPPKKDTDFASVEAAALGIAALRPSYMSVTYGAGGSTKGHTI
KLANEIQEKYGVPTIAHLTCVCANKDSIRTALSEMKNAGIENILALRGDIPKNYDGQVFT
DFAHASELVKLIKESGDFCVGGACYPEVHPDSANKQDDIANLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRIREAGIAVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEVAAGIQANLSDILLV
>G0I6X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pseudopneumoniae (strain IS7493)|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQILDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1C5P415|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MNIANLFQSKKIVYSLEVFPPKKTSSVDTIYNTLYGLRGLPADFISVTYGAGGSDTQRSK
TCEIASLIKSEYQIEPVSHLTCLNSTKEDIRQTLDSLKANGIQNILALRGDKGPAVTPKN
DFTHANELAEFIKAYDPSFNVLGACYPECHCDSETIDQDIENLKLKIEAGASHLITQLFF
NNNHFYEFMDKAIQKGITVPISAGIMPIINKSQIERTVSMCGASLPRAFSTMINKYADDP
QALKDAGIAYAVNQIIDLISNDVRGIHLYTMNNVETASRITESIENIIKSQNRITKR
>A0A3N7GH48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus sp. BP8|TrEMBL
MPVPATSFEFFPPRNLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVDATREETLQIVQEYAAAGVHEIVALRGDAPQGQERFTPHADGFANSV
ELIEAIAARGDMTIRCGAYPEPHPESPDTAADVAWLKRKVDAGASSAMTQFFFDAETYFR
FRDACVAAGIEAPIIPGILPIQSWAGTRRFAERCGTSVPQWAEEAFAAAGKEGEAQLALD
ICVRLCERLVEGGVDRLHFYTLNKPELVLKVCTALGIEPKGEFSRVA
>A0A739C5M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. arizonae serovar 48:z4,z24:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>S4MI42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces afghaniensis 772|TrEMBL
MTTSRTTFSFEFFPPKTANGERALWEAIRRVEALRPDFVSVTYGAGGSSRDRTVAVTRRI
AAETTLRPVAHLTAVGHSVAELRHIIGAYADAGIRDVLVLRGDPPGDPRGEWIPHPDGFT
HACQLVELVRSLGDFTIGVAAFPEGHPRSPDPETDLRHFVAKCKAGADYAITQMFFHVED
YLRLRDRVAAAGCDTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAARDDPGAAY
RIGVDHAVAMAERLLAEGAPGLHYITLNRSTAALDIHRTVQASRSLSAR
>A0A2A2L8H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diploscapter pachys|TrEMBL
MTNAKDLAQGKPKPMNGDALKKIDSLSAIPYIGSETLQSAPSPRVSTDHDSLVQRDYVAL
HEKINRRIKDGVPFFSLEFFPPKTANGVANFFTRLDRYNEGGPLFVDITWHMGSNPANMA
KETSSSSIAAGCLNYCRVDTMLHMTCAQYTKEETIRHLEQCKSVGLRSILALRGDLPPVT
EEDQKPVYKYRALDMIRWVRAEFGNYFTIACSGYPLGHPEAPSYTADLQYLKAKVDAGAQ
FIITQLFFEAEVFEKFVRDCREIGITVPIIPGIMPIMGYESIRRIAALSQLTIPDWILKD
LEEIKNDDDAVGRYGTVKAVEMCRRILKNGSASSIHLYTMNREGFCREILQELGLWQKRP
GRTLPWEPHGPNHPTRCKEDVRPIFWSARPKSYIYRTRDWDEFPNGRWGNSSSPAFGDLQ
DYYLFYLKTPANKDGQLKMYGETLKNFDDVKKVFVHYISQETNESGVKVTCLPWAEQESG
IAPETSLIKDQLLWCNENGILTVNSQPSVNGAPSADPLVGWGKPGGFCYQKAYLECFINE
KHVNALMEIIGEYDPRINYHFINRDGSVDKMNYEKTTPIAVTWGVFPGAEIAQPTIVDPI
AFRYWKDEAYDMWLKNWAWLYPKDSPSRAVIQEIHDKYYLLTLVDNDFPKPSILFEVLHR
AVEIANKKEGK
>A0A1M5W4K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium collagenovorans DSM 3089|TrEMBL
MRISKLFDEKDLVISIELYSPSCIGSRDYIFRTLEAMNGLKPDYMSITYRDFRGINNSIT
YKEDMKCLLDIRDDYRIEVLPHIIGHNVNKEVLCEIIQEVYENQIENLLILQGKELLEKD
LNKKGMSKDFKDILELINFIDKKNKFSISSVCYPDTFISQKDMEHDVNNIVKKVKSGASH
FICKPQFNNSNIYSYINTIDQKQLKIPIEVGILPITNFMQLKMLNLYFNDLIPSKVLKML
HKYANDEKSLRDIGITYALYQIEELIYSGIDGIHIYLIDDPYVTKRIFQGLNKILRKNNG
R
>A0A446CCH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter veterisilvae|TrEMBL
MSDSISPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGATRQDLRDILQAYRNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVAKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVDVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGLHFYTLNHAEAPLAVWKDLSLLD
>A0A3E0TVQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassotalea euphylliae|TrEMBL
MTYSHARQVESLNQSLSEISNDINVSFEFFPPNSPQMETTLWNSIERLAPLKPSFVSVTY
GAGSGTRDRTHDVIKRIQKDTALLAAPHLTCIDAGRDELIQIAKDYWESGVRHIVALRGD
LPDSSEKPSMYAADLVELLKSVADFDISVAAYPEGHPEAPNPQFDLLNLKRKVDAGASRA
ISQFFFDIESYLRFRDRCASVGIDVEIIPGILPVTNYNTLKRFAGLTNVHVPSWMPKMYE
GLDDDETTRRLVGANIAMEQVKVLHKEGVKDFHFYTLNRAELTYAICHTLGIRPK
>A0A6J6ASW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MEIRSAKKAVTYSFEFFPPKDVEGEERLWAAISQLESIAPDFISVTYGAGGSTRDRTIRI
TSEITAHTKIPTVAHLTCVGSTRDELLEILGKYRAAGINSILALRGDPTGGPRAPWVTTE
GGLNHADELVTLAAEFGGFSIGVAAFPDGHPASDGDIDKDVKVLIEKEKRGATFATTQFF
FEAKKWQHLVEKLDAQGSSMPIIPGILPVTNVKQLNRMAELSGVPIPDHISDAFHSVESN
PEDVRKLGVDIATQLCKDLLDAGAPGLHFYTMNTSTATREIYSQLKDH
>A0A6J7EWM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MAKIGDLLRIGRTFSFEFFPPRTDDAQLTLGRTIAELEPLRPAFVSVTYGAGGSTRARTR
DVVTWVRRETNITPMAHLTCQGHTRTEITEILDHYRDADVHNIMALGGDLPSDPADIRPS
DYTYASELVAEVNGYGYFSVGVAAHPEGHPRSPDRATDRRRLADKLRHADFAITQFFFEA
SHYVRLVDELMALGVDKPVLPGIMPVTNKGQIVRMAEMSGTALPSWLVERLNGTDDPHEI
RKIGVDVATTLCEDLLAAGAPGLHFYTLNRSTATREIYANLNLSSMH
>A0A6G0WMY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces euteiches|TrEMBL
MKIIDKINDKIEKKEVFYSFEYFPPKTPAGVTNLYSRMDRMALLEPLFCDMTWGAGGSTA
NMTIEISSNAQKFSGLEMLMHLTCTNMPKGSIKNALDSAKDAGIQNILALRGDPPRGQTE
FKECEGGFSYAIDLVKYIRQEYGDYFCIAVAGYPEGHSDCKDVDTDIQHLKAKVDAGADF
IVTQLFYDVPKYLEFVAKCRAVGITVPIIPGIMPIQTYNGFVRMSSMCPHVPEEIIQSLE
PIKDNDEAVKDYGVQLGIKMCRELLDNGVPGLHMYTLNLERSTRLILEGLGLNATSRREL
PWRQSTLAKRAGESVRPIFWANRPKSYLDRTASWDEFPNGRWGSSESPAFGELNESYYLH
TTTSAQERKAMWGESPVTLEDIYETFTRYVMGALKTLPWCDTPLNLETKSIQEHLASINR
AGFLTINSQPRVNAAPSDDPMFGWGGPGGRVYQKAYVECFVSPENLKRVIEKCNKMKHIQ
YHAVDVRGNSYSNSGKGTTAVTWGSFPNKEILQPTIVDTDSFMAWKDEAFSLWLSMWASI
YHDESPSHALIHQIHDTFFLVSIVDNNFVNGNIWDAFDVTAGP
>A0A6J7M699|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MREEGAGAGSDASRRSLGEVLSTGSRSFSFELFPPKTDDGERALWQTIRDLQGLSPSLIS
VTYGAGGSTRDRTVRIVGGIAAEPALTPLAHLTCVGASRDEVRAVVDEFAAAGVRAILAL
RGDPPGGPGSAWVQHQDGFAHADELVEFIASMGNFSIGVAAFPEGHPESANLADDAVVLA
RKQDAGAEFAITQFFFDARDYERLVRDAAGHGCTMPILPGLLPVTNVAQIERFAALSGAA
FPADLAARFALVKDDPDAVHALGVEVAAELGQKLLEMGAPGLHFYTLNRSASTLEVCEAL
GLGAR
>A0A3S0GBD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MYSARLWSVRHARSLRKLYEFFSRLAPLCAPLAKVVGARRLEVLLRPVEREAKGFLFDCK
MCGQCVLSATGMACPMNCAKEMRNGPCGGVRPNGHCEVKPEMRCVWVEATSGTKQIATDH
KAHPTPLLPAVDQRKRGSSTWIQVIHGRKDPAFQPPVGEKTTPEAEESPLEIACRSGKFV
VTVEIAPPDSADPAALLARAERFRGLVDAMNITDGAGGNCHMSSVAASAILTHAGFNPVY
QVACRDRNRIAIQGDILGASALGVKNILCLTGDDVSQGDHPQAKPVFDLDAVSLLHIARG
MVDRGEYASGRKLETAPKLFIGATCNPFVPPFTDRIANLEKKIVAGARFIQTQFCFDLPL
LEAFMAEVRARGLHKKARIIVGVGTLSTAKALRWMGNHVPGVHIPEAVTARIAAATDQKA
EAKRICIETIQAIRAIEGVAGIHLMGHKNDDTLVEIIIESSVRESHKHAFNQ
>A0A1Y4T2F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilimicrobiota timonensis|TrEMBL
MKISEILKKKATISFEVFPPKNKEGDISSIYYTIEELSHLNPDFISVTYGAGGSTKGKTV
EIASTIKNQYHIEAVAHLTCISSTQQEILDICQQLKDNNIENILSLRGDYPQDGLQHELA
FHYAKDLNQFISSHFPDDFCLSGACYPEVHQEASCLEEDLKALKEKVDAGAEYLITQIFF
DNHYYYRLVKEARKRGITVPILAGIMPVTHSKSLLRTAKLCGCSIPYELSTMIESYYHYP
QAMKEIGINYATHQIIDLITNGVDGIHIYTMNKPEIAKAIFQNIPTVLKELNHE
>A0A7Y5GQG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriaceae bacterium|TrEMBL
MKSFRERLENEIMVFDGGTGTYLYEKGIYINRCFEELNLVSPELVQEVHRDYINAGADII
ETNTYGANRFKLQPHGLDERLYEINFKGAELAKAVAGDSALVAGSVGPLGVQIEPLGKIS
FDEAKEYFKEQVKGLIDGGADLIIFETFALVKEMIQGVRAVREINPDIPIIAQVTINEYG
TLISGAPLSRFIEKIEEYNVDVVGLNCSVGPKLMLDALEELRSRTNLPISVQPNAGFPQS
IGGRNIYLTSPEYIAEYAKRFIQTGASIVGGCCGTNPSHIRAIRRAVQALRPAKRVEVKS
SGFAIEAPEEVTPYKKEDKSRLCNKIKSKQFVSLVELVSPKGVSAKKELEKARKLFYYGI
DAINIPDGPRASARMSAMALAVMIQREVGIEAVLHFACRDRNVIGMQSDLLGAWALGVRN
ILAITGDPPKLGNYPDATAVFDVDAIGLTNLLNRLNHGLDLGGNPIGDPTGFSIGVGVNP
GAINLDEEIRRLDWKIEAGAEYMITQPVFDIRILENFIKRIEYVNIPLICGIWPLVSYRN
AEFMNNEVPGASVPIDIMERMRKTNTKEEGFNEGVTIAKETFEYIKGSVAGVQLAAPLGR
IDAVFKILGKEVN
>A0A4U2MZA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus wiedmannii|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESIKRATLNITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYGATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGILISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6J6GZ62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MERMTVSVEFFPPKDDAGEARLWEASTALESISPDFISVTYGAGGSTRDRTVQITKEITK
RTGRSTVAHLTCVGSTKDELIEILGQYKSAGIKSILALRGDPVGGPAAKWVSKPGGFDHA
DQLVELAMGQGGFEVGVAAFPDGHPASNGNLAKDIDVLLSKEQLGATFATTQFFFESSKW
ETLVSELAKRGSVLPIIAGILPITNVKQLHRMAELGGTAIPVQVSKLFNEIADDPEAVKR
AGIELATNLCNELIALKVPGLHFYTMNSSPATLEICTNLGLTNRE
>A0A6J6I416|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MSETSLIRQSNLNSLDFVAVSEVSAARKSSGEPTLSYEFFPPKDEAGEENLWASFEILME
TQPDYVSVTYGAGGSNREKSLAVVDRMAKRVLTIGHLTCVGASEAGTTEIIRRFETAGVG
AILALRGDSPKDDPDALTKGDLKTALELVELVNRETALEVGVAAFPEVHPESKDMAHDSA
VLKLKESAGASFAVTQLFFSVEAYLALVHSAKNAGVSMPIVPGVMPISNAKQVIRMAELS
GAAIPDELLAKFDSAQNDDQARKIGMDYATQLAIDLIAAGAPGIHIFTLNSHTAAIELAR
GAGLCR
>A0A1G6AW49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium oxidoreducens|TrEMBL
MNRVNLLFDGGTGTYFAQKNHKMGLGSEYANLSNPKLIREIHTEYLEAGCNAIKTNTFAV
NRIAMAGDEEKVKEIIAAAWENACAAVKDYEAEIFADIGPISNLSEKSDVAKEYCFVAQI
FLELGAKKFLFETNANTEGLKEAAAYIKQRCPDAYIITSFAVLPDGYTRDGAMVSDLLEE
IKACKDVDVFGLNCVCGARHMLSLIQDLNLEGVTFAAMPNAGYPIVINNRTFYDGDPKYF
AEQLAKMAALGVKILGGCCGTTPAHIEFTKKALDGIPQIVSKPANHKEEESLSARLESPF
WNRLKSGKKVVAVELDSPANTNLDKFMSGAWELKGAGADIITIADCPIARARMDSTLLAC
KIKREMNLDAMPHMTCRDRNLNATKALLLGSYAEGIRNVLLITGDPIPTAERDEVKSVYQ
FNSRKLAGFVGSLGKNVLPDEFHMFGALNVNAVNFDVQIRLAKEKMERGIIGFLTQPVLT
KEALDNIKRAKQELGAYILGGVIPVVSARNARFMNSEISGIKVAPEIIERYEGKDRAQSE
QLAIEISVDIMKKISPYVDGYYLMTPFGRTRLIAEILKAFAEQEEV
>A0A6J7JXI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MTLRELIDNRTRPIVTAEFPAVNGGGLEAIRAKLEPMLPFVDAINATDNPAAHAHASNVS
IAIALKTLGAEPIMQVVCRDKNRLALQADIVGAALFGVENICALTGDDVTAGDEPEARRV
FDLDGPQLIAVATRLGQGQYLSGRTLTPAPTLLVGAVENPAAPPLKYRVERAALKSDAGA
RFLQLQICYHPDRLAAFVAGCVERGIDTRTALLPTVCLTKSVHSLAFMHDRVPGIDVPQE
IRDRLAAAPDAAEESYQITLELSRHALSLTGVAGLHITDFRHDGSLGRLVTELGLRPDVV
ATTA
>A0A094QZ18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRPEKTMYSFEFFPPKDLAGEERLWQALETLAHHTPDFVAVTYGAGGGTRDRTIRITSEI
TARTKIPTVAHLTCVGSTRADLIEILNRYTNAGIKSILALRGDPVGGPRAPWTPVDGGLT
HADELITLAKEHGDFTIGVAAFPDGHPNSGGDFNKDIDVLLRKESLGASFATTQFFFEID
KWKRLVDTLESRGSELPIIAGVLPVTNVKLLTKMAELGGTPIPQSIAARFAAVEANPDDV
RKLGVEIALDLCNDLIDAGAPGIHFYTMNSSTATSEIFTSLQDRR
>A0A419H616|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriales bacterium|TrEMBL
MKVIEHLYKAKNPLISFEIIPPKRGGNVRQLLHVLDDIVKYNPPFIDITSHAAEVMYEET
SDGGMQMKVKRKRPGTLGLCALIQNKYNIDAVPHVLCSGFTREETEDFLIELHYLGIDNV
LAVRGDDSAFKKPLKFGRSMNEYAVDLVKQINSLNKGKYIEDGLLDAEPMDVCVGVGGYP
EKHFEAPNLATDIKNTKEKVDAGASYIVTQMFYSNKFYFNYVDQCKKEGISAPIIPGLKV
ITSKAQIKSIPKNFFIDIPQELAEEVEAAKPEHVMEVGVEWTKKQVEELLNKNVPAVHFY
VMQNSQPIKLLMNKLKL
>A0A5C9BZ20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MTTEISIEFFPPQTPEGVDKLRAVRAELAKLNPAFFSVTFGAGGSTRERTFAVVKEIAAE
GYDAAPHLSCIGSTRDNIREILNEYKAAGIRRTVALRGDLPSGMAETGEFRYANELVEFI
RAETGDWFSIEVAAYPEWHPQARSPKDDLDAFARKVKAGANSAITQYFYNADAYFHFVDE
ARALGIDVPIVPGIMPIVGFTKLARFSDACGAELPRWMRKKFESYGDDSDSIRAFGLDVV
TELCERLLKGGAPGLHFYAMNQSALTTEICRRLG
>A0A434C5I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.T.Ca.TU.009.01.3.2|TrEMBL
VKRILTETAIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGGPYRPHP
GGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRAITQFFF
DNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFEGLDRDP
QTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAAGSAAA
>A0A3B7MLW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraflavitalea soli|TrEMBL
MFLNKIRTGESGIVTYGITPPKKTETDPLRMAEIAERTIARILPLDIDALVVYDVQDESA
RTPVERPFPFMNAHDPFEFASTYLQDLRIPKIIYRPAGKFTRDELSEWLDDLHKHQFYPV
FVGVPAPDFAVKTSLTEAYELWSKNKRTSVIGAVTIPERHAVLKDEDKRILDKAACGVSY
FISQCVFNVDYAKKMIEDLAHTCKAQNAPTPTIIFTLAACGSVKTMQFMDWLGIHLPESM
QEELTKAENMLDRSVGICLEIAAEMITYCSERSIPFGFNIESVAINKKEIEASIYMVNRV
GEMLENKGIRKRSVLPVP
>A0A3M2KVU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia stercoris|TrEMBL
MPFSVEFNPPRDAAAEARLWRAAREFECLHPAFASVTYGAGGSTRERTARVTGQLARETT
LLTVAHLTAVGHSVAELRSIMGAYADAGIRNILALRGDPPGDVLGDWVRHPEGLEYAEQL
VSMVRGLGDFHVGVASFPQGHHRSPDLDSDTRFLIAKLRAGAEYSITQMFFEVDHYLRLR
DRVAAADPIEGAKPIIPELMPITSLRTVERAEELSGRPLPRHLVARLEKAAGNDPEGNRD
AVRAVGIEIATEIGQRLIDEGAPCLHFITLNFAKATTEVLTNLGYRVAPASAPA
>A0A101SC34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces canus|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPMAEWVAHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWEGDVTHFVD
KCRAGADYAITQMFFQPESYLRLRDRVHAAGCETPVIPEIMPVTSVRMLERLPQLSNAII
PSALKERILTAKDDPTAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A143Z3Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichococcus collinsii|TrEMBL
MKIRDMISKGEPTVSFEIFPPKSSYSLDTVFDTLHDLKDLHPDFISVTYGAGGTAQSNTV
EIASRIKKDFGIESIAHLTGCTSTKEGMKRTLASIKESGIENILALRGDIPQEKLADKNW
HPEYRYASELIDDIKAAGDFSIGAACYPEGHVDSINKVDDLKNLKRKMDHGADFMITQLF
YDNDLFYQFKEKLDLVGIEQPVIAGILPVLNIKQVKRIQEISGCNLPPKFLRILDRYAHD
PASLQEAGIAYAVDQIIDLLSSGVDGVHIYTMNKPDATRRIMENISCVRKAVCRKEPQR
>A0A4U5JS10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas gilva|TrEMBL
MQTPISFEFFPPKTDEQREQLDKVALRLKKLSPEYVSCTFGAGGSTLDYTPETVQRLHHT
HGLDAAPHISCVGGTRAELGALLQRYKDMGCRRIVALRGDLPSGMGHTGDFRYATDLVEF
IRREHDGFFHIEVGCYPETHPQSEHAMADLKHFKAKIDAGADGAITQYFYNADAYFRFVD
DARKLGVTVPIVPGIMPISNFSQLRRFSETCGAEIPRWIGKRMLAYGDDVEAIRDFAADF
VADLCRRLVDGGAPALHFYTLNLSKPTLSVLSRLG
>A0A439H308|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEVRLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVRRILNETTLTPAAHMTCVDAARHQVDAVISEFAEMGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVHDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHESEAA
GSAAA
>A0A440R0G4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MSIRHQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVF
LGAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIAGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>A0A7X3GE53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. MMS18-CY102|TrEMBL
MLKQSILNKKTGIITYGMTPPKNTHTPEKIEEISQKQIERLAGLDIDALILYDVQEEADR
IDEERPFPYLPTLDPEIYSKQYLASLDIPKIIYRCVGKYSEAELAEWLKKETEQQRYTVF
VGASSSQQQVQLQLSDAYRLSKQHNDQMTFGGVIIPERHMKKNDEHIRVVDKMQRGCDFF
VSQATYNVEASKNFLSDYYHHCQQHELDMVPILFNLAPCGSTKTLEFMKWLGISIPKWLE
NELKFSSDVLDKSIQLTQKIFEELLEFGLEKGIPVGCSIESVSTRKVEIEASIEMVKDIK
SMLDRKQLVDAVR
>A0A7X3KEP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. MMS18-CY102|TrEMBL
MKQDLREALQHRILAGDGAMGTYLYQTGFPVGVSYEEFNVLRPEVIGGVHRRYYEAGARL
IETNTFSANAEKLSKYGLESDIELINRSGVRLARASVGADAYVVGAVGPIRAARRKGVRT
ATVQHALSQQIGILLDEGVDGILLETFLDMEEMLLAIRAVRQSSNVPVICQFAVEDRGST
QDGIGLIDAFNRLQSEGADVVGFNCRTGPNGIMRSIDSLDGTIQLPFSVFPNAGIPDYVD
GKYTYSATPAYFGETARRFADRGARIIGGCCGTTPEHIAAIAAALDGYTPAALDAVPVAE
APAAPQHEGGPSVTVSSTPVPPVAPPAEEPSIVELVQQRHTVIVELDPPRDLDITKFMAG
AAALKEAQADALTMADNSLAVTRMSNIALAALVKERTGIRPLVHIACRDRNLIGTQSHLM
GLDALGIDHVLAVTGDPARFGDLPGSSSVYDMTSFDMIKMIRQMNEGKAFSGKQLKQKAK
FVIGAAFNPNVKHLDKAVQRLERKVASGAGYIMTQPVYDPALIERMAEATKHIQVPIFVG
VMPLASGRNAEYLHNEVPGIQLSDEVRQRMAGLEGEAGRAEGVQIATELLDAIIPHFKGI
YLMTPFMFYEMAVKLTEHVWHRIGRFMNEA
>A0A850PBI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ameyamaea chiangmaiensis|TrEMBL
MTDRLNGLVSEDRINDLLSCNRDMPPPALSFEFVPPRTEPMERRLWQCIPRLAPLSPRFV
SVTYGAGGSTQASTYATVLRLSRETDLVPAAHLTCVGATREEVDAIARSYWDAGVRHIVA
LRGDPPVGAAGYTPHPGGYAYASDLVAGLRRIADFDISVAAYPETHPAALSPDADLDNLK
RKLDAGATRVVTQYFFDASTCLRFLERCQAAGITAPIIPGIMPVSNYEHVARFSALCGVT
VPAWLTRLFEGTDGDLELRRLVAGVVAVEQIRTLQGNGINDFHISTLNRAEPTYAIAHIL
GLRETGRCVVDNAIDYSEHEEARDEREAETESDAPGRAEEGASPFMLRTMFG
>A0A527KLV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKTDEMEARLWDTVTRLEPLKPNFVSVTYGAGGSTR
ERTARTVKRILTETSLTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPGGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQKDPQTHALVAAAVAAEQVLDLVERGVGDFHFYTMNRADLAFAICHMIGIRSHEAEAA
GSAAA
>A0A1E4ZS90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|PVC group bacterium|TrEMBL
MFDSSIDLSLEFFPPKTEALLESLKKTLFRLKRYNPEYVSVTYGALGSNQEKSLSIVDHI
QNKENIPTTAHFTCVGMSFEKAHAFLKELNSLGVSKVLALRGDIPSNVDLKSVFTDFRYA
SDLVSFISEKYPHFDIFVAGYPEKHPEAKSLETDIEHLKKKVDQGAKAVITQLFFDNDHF
FRFRDKAQDLGIKCKIIPGIMPVTSYESIKKITQMCGVHLPKDLELFFSQDRNQQELDRF
AVDFSLRQCEGLLEGGVDSFHLYTLNKLHVIENICAFLRKEEL
>A0A7M3BPL7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
AWLAERFDGLQKDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGI
RSHEAEAAGSAAA
>A0A850PAZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ameyamaea chiangmaiensis|TrEMBL
MGRIAVELVPRDADNLLADARMVRDCFPVADTINIPDLLRLPLRSWDAARMVREAGLTGA
AVPHVRAIDIAPDGPLPGLDDPDLREILVVRGDPPADLRHTVYPNTAEDVIARYRRAAPH
LRIYAAFDPYRRAPYRELEAMRRKRDAGADGFFTQPLFDRKMLDLCLEWLRGESVFWGLS
PVIGPKSRSYWETTNHVVFPRDFAPTLDANIAFARETMRTVAAEGGSVYLMPLRVRLERY
LPPLLDLG
>A0A529LV16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
AFMQKARDLGHTEKLFLLCGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEG
KQLCIDIINEVKEIPGVAGIHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAE
RLDHILHDEITETQVDMVKTAH
>A0A178KIU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium jeanii|TrEMBL
MGYSHASHLDALNQNIVDLNGDLNVSFEFFPPSSEQMEKTLWASIHRLKTLKPKFVSVTY
GANSGERDRTHSIIKDIKEQTGLVAAPHLTCIDASREELRTIARDYWNSGIRDIVALRGD
LPPQGGKPDMYAVDLVELLRQEAEFDISVAAYPEVHPEAKSAQADLINLKRKVDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNMTQAKRFAKINNVKIPGWLEKQYE
GLEDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGVRAEVEIAQ
A
>A0A3G4VUM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ADI95-16|TrEMBL
MALGTASTWSDRAHTVRDLLASGSSYSFEFWAPKTEKGERNLWEALRRVEAVAPSFVSVT
YGAGGSTRGGTVRATEQIAADTTLTPVAHLTAVDHSVAELRHVIGQFADAGIRNMLALRG
DPPGDPMAPWVKHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVDK
CRAGADYAITQMFFHPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
DAVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A528E1X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MTAPQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFIQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDTVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A0D0D5H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paxillus rubicundulus Ve08.2h10|TrEMBL
MKISKKIEQSTKEGKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDVTWNAGGRTS
DLTSEMVKTCQGLLGIETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPAGKDE
WEAVEDGFVHGIDLVRHIRKEYGDYFDIAVPGFPQNQLLPPKERDLELLYLKQKVDEGVD
FIFTQMFYDVDVFIDWVKAVRRAGITIPIVPGIAPIQTWNGFLKATSLAKTVIPQSFMDA
LESHKNNDEKVREIGTKLVADMCRKILGADLGIRGLHFYTMNLERGTKMLLEELNLVPRI
ETVKPLPWRQSLTPNRRQENIRPIFWANRTKSYLSRTENWDEFPNGRFGDSRSPAYGELD
GYGVSLKQTKEVALKLWGEPRTFADVTDLFARFCEKQLTSLPWSDQPASSETSIIASDLA
KMNRLGFLTINSQPAVNGARSDDPNFGWGPSNGYVYQKAYLEFFVNGDLLELLISQIELD
SNMTYYVINKQGDLRTNTHSDGPNAVTWGVFPGKEIIQPTIVEAISFMAWKDEAFELGCK
WANVYEPGSPSRKLVMDIMNNSYLVNVVHNDFKDPGAIFIPFLKAGEEYVASHPQQHGST
ITNGVMN
>A0A1V5IMV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium ADurb.BinA094|TrEMBL
MTATEYKAGTNLEKILSEGKFAVTGECGPPKSADGSVIENKAKMLAGYVDAVNITDNQTA
VVRISSIASGYTAMQNGVEPIVQMTCRDRNRLAMQADLLGAHTLGIHNCLCLTGDHLSFG
NHPEARGVHDLDAINLIEMLRRMRDEKKFDCGEEMDVAPKFYIGCAENPFGDPFEFRAIR
LKKKILAGADFMQTQCIFNIPKFKTWMEEVRAEGLHQEIKILAGITPLKGVGGARYMKNF
VPGMDVPDEIVDRMAGVEKGPASHAEGKKLAVEMIKELAEIEGVAGVHIMAVEWEEAVPD
IVEAAGLLPRPTVA
>A0A441ZEN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A2E4IL19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MHPVASDPGQPLPILEGHVSAGRLERVLRSGKFAVTAEIAPPDAADAGAVYQRASVFDGC
VDAINATDGSGANCHMSSVGVCSLLTRKGYAMVMQVSCRDRNRIAIQGDVLGAAAMGVTN
ILCLTGDGVQAGDQPDAKPVFDFDCISLLQTVTAMRDAGEFLSGRKLTTPPRVFLGAAAN
PFGPPLDYRPIRLEKKINAGAQFVQTQYCFDLVRLREFMSRVRDMGLTERCYMLIGVGPM
PSARTASWIRDNVPGVHIPDAVIKRLLGAKNQKEEGVRICVEMIQAVREIEGVHGVHIMA
YKQEERVRDIVEESGVLEGRIPWYPGVSNDQQGQQT
>A0A1Y4USL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor sp. An112|TrEMBL
MKIIDILNQDRPTLSFEVFPPKTSDTYDSVAKATQDIAALRPDFMSVTYGAGGGTSDYTV
GIAAGIQQQYGVDVLAHLTCASSTRDHVAQVLEHLKENGIQNVLALRGDIPEGGAPAHDY
QYAAQLVRDIKAHGDFCIGGACYPEGHPESPTKNADIDHLKAKVEAGCQFLTTQMFFDNN
ILYNFLYRIREKGITVPVVAGIMPVTNGKQIARICKLSGTYLPERFKAIVDRFGDNPAAM
RQAGVAYAAEQIIDLIANGVEHIHIYSMNKPEIAASIQSSLSEVLK
>A0A418PH74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella parvula|TrEMBL
MTLREKHQQGQFTITVELDPPKSSSAEKTFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKEIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDAPTNFYIGATGNPGAPDLEIERQKLAAKIQNGA
HFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
MEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLYIIDHV
>A0A068RVX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lichtheimia corymbifera JMRC:FSU:9682|TrEMBL
MKVIDKINKAESEGRLFYSFEYFPPKTPQGVQNLYDRMERMQRFGPEFVDITWGAGGTSA
DLTTELVATAQSVYGLETMMHLTCTNMPVEKIDAALKAAKDCGCQNILALRGDPPKGQKN
WESVENGFSHAVDLVRYIRKQYGDYFCIGVAGYPEGHVDNPDKEDDLRRLKEKIDAGADL
IVTQLFFDADVFIHFVERCRAIGITCPILPGIFPIQNYNGLKRVISFSNNEVPQRIWDEL
EPIKDDDAAVKEYGINLTVEFVQKFRKAGVNGFHIYTFNLERSSRLILERLNLVPPLENV
KPLPWNPSLSSKRAKENVRPIFWKNRAKSYIRRTETWDEFPNGRWGDSRSPAFGELDGWG
VSLKYPQEECLKMWGEPKKADEIALLFAKYCKGDVAGIPWSAQQLEPETEIIRQRLAAIN
LLGFLTINSQPAVNGAKSSHKIYGWGPKNGYVFQKAYLEFFVSPDKLDELTAKISKDPQV
TYYAVNRQGDLRTNTQSDQPTAVTWGVFPGKEVIQPTIVEPMAFMAWKDEAYELWGEWAR
IYDRESESAKLILDIMNNWYLINIVHNDFQDENGIWRLFDLEVDQFADQSKHLLNGLVA
>A0A529KAB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
KDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAAGSA
AA
>A0A2I1TF79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella parvula|TrEMBL
MTLREKHQQGQFTITVELDPPKSSSAEKTFEQAARLKGKVDAINIADSPMSKMRMSPISL
SYLLQHNKKIETIFHLTCRDRNIIGLQSELLGAAALGVHNILTLTGDKPDNGDHPFAQSV
FEVDCMGLLNIAKTLNAGKDLAGNDLDSPTNFYIGATGNPGAPDLEIERQKLAAKIQNGA
HFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILDR
MEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHI
>A0A2M8CC30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium CG_4_9_14_3_um_filter_33_16|TrEMBL
MNLREKLAAKKFVVTVELDPPKTLNLDKILREINSANFRKVVDAVNVTDCPLAKLRMSPI
ALSHIIQEKIGLESIFHITCRDRNLLGLQAELLGASALGVKNILALTGDPPEMGDYTKAT
GVYDLDSVGLVKMVNKLNNGYEYKGEELKSRTDFFIGVAVNPSAQDLKKEIKRFEEKVSA
GANFVQTQPIYDIEILERFLEFTAHLNIPKIIGIMPLKSYKMIEYLNNNLPEIFIPSVVK
ERMIGKDIGEGIKISQEFIDKIRKFKEVAGIHIFPLRDMDLVCRLLN
>A0A5P2UW54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces subrutilus|TrEMBL
MASGTASTWSDRAHTVRDLIASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVRATQQIAADTTLTPVAHLTAVDHSVAELRHVIGQFADAGIRNMLVVRG
DPPGDPMGEWIAHPEGVRYAADLVRLVKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVEKAGCDTPIIPEVMPVVGIKQLDRLPRLSTALFP
VTVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A379JFC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKAEAGANSAITQYFFNADSYFY
FVERVQALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCETLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>S5P7X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter butzleri 7h1h|TrEMBL
MFKTLIQKLQEDKYLTLETTPQHEPSMHNIIEKIKKFNLQDKIDGFSCTDNPLAKLRYNS
LFAALKLQQEFEKPVIATMTMRDRNKIALQSDLLGANDFDVRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGHPFKIEPKQIFPFAVVNSYAKNFSSLEKKMHLKI
QNGAIGIITQPIFDIENAQKLLESFDIAKENVEGDKRKSQLIFGIFPVTKLRTALFLSAQ
VPGIHVPQFWIDALEKAHSIGEEEEYKVGMELSSNLFKELNKLHPKIHLMTANRFDVANE
IIS
>A0A800H9Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIRDKIKKPQRPVVAYEILPPREKDGTLNSYGEIISSLLSQTHIDAINIPEVLDEDGRG
KRPVVNQKRGEPREFGRLLQDIVGVEAIVNRVVVHEPFDAQMKWIEETNKDYEIENLIIV
GGESSNVKYPGPSVNEVLKSISGQYNENGGDIFCGGIAIPSRTAESKNLITKSENGSEFF
TTQVLYDSSNIIKMIGHYQERCDELNTFPRRLLLSFAPVSSQKNIEFLKWLGVEIPSETE
RYLQGRPGSMIERSLDVAIEVLNDTLRSITEKN
>A0A8D0AIG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sander lucioperca|TrEMBL
MVNQVQRGDGSWQSCKSDSSGASNSSESSKESSRSSTPVLDVDRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGTGGPLFIDITWHPAGDPGSDKETSSLMIASTAV
NYCGLESILHLTCCNQTKEKISGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATD
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNY
GIKQAVEMCRVLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LKMWGDELMSEESVYEVFTCYITAQPNRSGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIAGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVN
YHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKDEAFALWIEQWAK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLESCLWKVIDDMFELLDATPEPLDATPDCK
KKQLMTFLITRFTL
>A0A423LKZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETADHFHIEVAAYPEMHPQARNYEDDLANFVRKAKAGADSAITQYFFNADSYFY
FVDRLQALGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTRSIQSFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A5E6S2N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSLLKTALHEHAFVCIMEFVPKPSAERFAALEAIMARKQLCGWPLTVSIGDRVGSPLDMS
PLDAFNSLATPVPALLHFSGKARERHDLLSQLQHMDAAGLDQLLILTGDRLPGHTPGQQP
VRYLESVAALQIARQARPDWLLGAALNPFKYREEEGAAQYLKAEKKLSAGADFLTLQLGY
DDQKHQEALQWMARQRTPKPLIACLMALTHGRAQMLEHVAGAVVTPSMRDVLAAELALSK
AYAQARSIQRLALQVVGLKLMGYAGVHLSGVHEITQLQALEDELEQVLASVHTLEQWAPA
WAASWQMPDLPAVTFTPPGAPWRLGQSRVSASLREQVRYHLLSSMHGLLFGRENRASRAF
GWAVTRPLWSKPGAASLLHGLERGIKRPLVGCDTCGSCRLQDTLYICPESCPKGLANGPC
GGTSLNRCEFGDRECVHGVKYRVAKTVGETDVLRERLISCVEVENRHRSSWPVWFQPAPV
VKVEPVVAVRRAAGSESVQREVAEVDN
>A0A7V1EPG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVTNIIKDADRPLFSYEIMPPLRGGSAEKIFGLVEELMPYNPPFIDLTSRSAEIEYFDT
PSGKFERHVRRKRPGTIGLSAAIKNRFNVETVPHLLCNGFTREETEDALIELNYLDILNV
LAVRGDDLRRKVDTRHKTINLYAKDLVSQIVEMNDGKYLDELLDASVTDFCIGVGGYPEK
HFEASD
>A0A3Q8WB01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas venusta|TrEMBL
MSSQEHPLGISFEFFPPSSDAGREKLMHVRDELAARQPRFFSVTYGAGGSTQARTSDIVR
TVSQSGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIREETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
HFVEKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDAIAAF
GTDVVSRLCERLLDGGAPGLHFYTLNQAAPVLKIVDNLRG
>A0A0R3RK04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elaeophora elaphi|TrEMBL
LFASAVSFSSIIPQICGKKGSESRTDWIANGTYVPLRDRIKKRIAAGVPFFSLEFFPPKT
ANSVANFFARLDRFREGNPMFVDIAWHFGSDPGNINSETSSSSVAAGCLDYCGIDTMLHI
TCCPYTKEQSIRHLEQSKALGLKNILALRGDLPRQVILYKYRALDLIRWIKEEYNDYFTI
ACTGYPAGHPEAPSYQADLLYLKAKVDAGADFVISQIIFDGKVFENFLRDCREIGITVPI
IPGIMPIQGYESIRRIAELSQLIIPDSILANLEPIKNDDDAVRNFGIRHAVDLCQTLFTG
GSAKSIHLFTLNREASSREILQQLGLWPRSPVRALPWRSFGENHPVRYKEDVRPIFWSMR
PKSYVFRTREWDEFPNGRWGNSSSPAFNDLKDYYLFYLKGQPTKDEQLRMYGERLETLAD
IQKVFVNFIAQNINENGVKVSQLPWNEQHDGIRAETSLIKDQLLWCNSNGFLTINSQPSV
NGAPSTDPFVGWGKPGGYCYQKAYLEFFTSQANAEVLWNLLPSYSRLNCHIVNHDATIDW
TNTETTMPIAVTWGVFPGSEIAQPTVVDPLSFRVWKDEAFGAWLNWYIFFWLKNEKIYNE
YCLVTLVDNDYPESTVIFDCLAQLVNLLKK
>A0A2E2DIZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivoracaceae bacterium|TrEMBL
MKRISFEFFPPKTDAGKEKLLATQKKLLAKNPDFFSCTFGAGGSTRDNTRDMVNKLRAQH
GDTAPHLSCIGQSKDEILELVNGYKEAGVTRIVALRGDLPSGMGYAQSEIKYADELVALI
RQETGDHFQLEVAAYPEMHPEARSFADDIDHFKRKIDAGANSGLTQYFYNADAYGYYLDA
LQKIGCDAPVYPGIMPILNVANLLRFSANCGADVPRWLSCKLNDLKDDDAAVKAYGEEVV
TRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGL
>A0A2E5MCB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIRDKIKKPQRPVVAYEILPPREKDGTLNSYAETISSLLSQTHIDAINIPEVHDEIGRG
DRPVTNQKRGEPREFGMLLQDIVGIEAIINRVVVHEPYEEQMRWIEETNTTYEIENMIIV
GGESSKVDYPGSTVNEMLQSIAKRSNSNGGDIFCGGIAIPSRKDESKNLIRKSEHGSEFF
TTQVLYDAENINKMINNYQSRCNELDTFPRRILLSFAPVSSQKNIEFLKWLGVEIPDDTE
RYLKGRPGSMTERSLDVAVEVLNEILDFITVNNLKVPVGLNVEHIMSYNFQSSVEMLQEL
ARIYREFCIKTQQYS
>A0A4R5BJG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora karakumensis|TrEMBL
MESELRRSLDRMRYEVLPVGNPRVEALDPGSTVTVTASPAKGIGPTLDCAERLAAMGLRA
VPHLAARSIRDHAHLTGVLDRLDAAGVSEVFVIAGDAAKPLGEFADSLALLRAMERMGRL
PARIGIAGYPERHAFITDDCAVRAMSDKSHYADYVVSQITFDPRTIIDWARDLRNRGVEA
PVHVGVPGVVDAHRLLRIALKIGLGESTRFLRKQYGAVSKMLARYTPEELLDELSPQLGD
PDSPIAGWHLFTFNEVTRTVQWRDDLAARLSDYADRPA
>A0A5E7SAR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLAKYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1Q6ENY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium sp. 56_9_plus|TrEMBL
MHSPMFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVS
EYGIPSVAHLTAQYLNKDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFEHASDLAV
YIRQQRPDMKIYGACYPEKHPQSATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KARAAGIDVPIEAGIMPVMNAKSVLNMSNKCQSKVPEKLGIMLDKWGGDKALLKEAGIAY
ASEQICDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A2S1QX75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium album|TrEMBL
MKVTEHIENAKGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFKPPFIDVTYHREEYEYKE
LPNGLLEKRVVKKRPGTVGICSAIQNKYQLDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VVALRGDAVKREIYFKPEKEGNHYATELVTQIENLNKGIYLDDHLQNTSATNFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGASYIVTQMFFDNKKFFDFVAKCRKEGITVPIIPGLK
PISTKKQLNQIPHRFKVDLPDDLIMAVVKARDNDAVRQIGIEWCTQQSKELVAAGIPVLH
YYSMGKPDNIKAIAKEVF
>A0A1G0AKE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteria bacterium GWA2_35_26|TrEMBL
MKVTDHIAAAKGETLFSFEIVPPTKGTSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVN
KGNGLLEKKLTRMRPGTLGICASIKHKYHVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFIPKEGGNHYAADLVSQIHQLNQGNYLHGLKDIEHKSDFCIGVAGY
PEKHLESPSLTSDLKRLKEKVDAGADYVVTQMFFDNAKFFEFVAKAREIGINVPIIPGIK
PIAVHRHLQILPQIFRIDLPEDLINAVEKCKTPADIRQVGVEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASKVF
>A0A1F9AI89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_52_11b|TrEMBL
MTFKESLASKEFVTLAELQPPKGTDLSETFQHIERLKGRVDAFNVPDLQTGIMRLGSLSA
CALLKSKGVEVIFNLSCGDRNRLALQSELLNASVLGLKNILLLQGDPPSLGDHFDSRPVF
DLDVLGLLEAAKKLQEGYDLAGNVLKGKPFFCTGTLVKASANGPALDLEVMNMEKKIELG
ADFFLIDSVYDLAVLGSFMKKVSHLKVPVVASVTLLKSVGMARYINQHLEGAKIPDAIIN
RLMKASDKQKASIEIAGDLVQGMRSLCRGVQVVPIGWENLVPAVLDHAGL
>A0A1I0CE21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter segnicrescens|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGREKLQTVRDRLAEVHPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRESIAELLDIYRESGVNRIVALRGDLPSGMGASGELRYAN
ELVAFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKMNITIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSDNIRK
FGEEVVTRMCERLLAEGAPGLHFYTLNQAEASLNIWNNLGLANRDKISF
>A0A5E7ST76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLLATARQLAIYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLAQYKAAGIKRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDVANFVRKANAGADSAITQYFFNADCYFY
FVERVRALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1Q3L9D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. 69-10|TrEMBL
MSRVPFSFELYPPRSTASAQALHDTIDRLAEAGPDFLSVTYGAGGSTGGRSLEVLRYIRT
RTDVEPLAHLTCVGNTYAGAARLIREFLDAGILSFLALRGDPPAGLGEGESFLGDLESSA
QLVQLIDRVQAERAPYEESPVPGNPGAVRVAPRRRVNIAVAAFPNGHPRSAYSSQHVDAL
LAKQAAGATLAITQLFFHPDHYLAFVERARRAGVTIPILPGIMPITSPSRLARVLELTGE
ELPGELSIALEVEPTAEGRRQIGIDWASDLAREVVAGGAPGVHLYAFNQHETVLDVLAQA
GILADRCLSPATK
>E6MNP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella salivae DSM 15606|TrEMBL
MKVTDIIQQNKDRRRFSIEVLPPLKGNGTATLFATIDKFRELNPLYINITTHHSEFVYRE
LPNGQFTRNRIRRRPGTVAIAAAIQSRYQLPVIPHLICSGITAEDIEYELLDLQFLEIEN
LLLLRGDKAKDDRVFMPTPGGHSHTTELISQVNRFNKGLFNDGTSINHPGVPFEYGVAAY
PEKHEEAPNMKMDLEWLKEKQDMGASYAVTQLFYDNKKFFDFIQAAREIGITIPIIPGIK
PLARLSQLTVVPRTFRCDLPEELASEVLKCKTDEDAQHLGIEWGINQCRELYEAGFHNIH
FYTVSAADSVREIVRKLL
>B8KU68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luminiphilus syltensis NOR5-1B|TrEMBL
MAPHLSFGADDEAAMAALLERYREMGISRLVALRGDIPSGMGGGGHLVHANELVDFIRRH
SGDHFSIAVAAYPEIHPQAKSYETDIFYLKQKLDAGADKAITQFFFNVDSYFYFLDRCQA
AGIEQPIHPGIMPIVNFTNLERFAGSCGAEIPRWIRQRVAGFGDDQESVRKFGIEVVTQI
CATLQESGAPGVHFYTMNQVEPTLTIAANLGLIDTP
>A0A2E9KSX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKISEIIANYKAQGKTFYSFEFFPPKTDFGLDNLYSRIDRMASFHPAYIDITWGAGGVTA
DKTLEISKTINKYFGLEVMMHLTCTNMQVSSIKKVLIEAE
>A0A1M6HV50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces denticolens|TrEMBL
MSTTPDDSAPAPYGAPTLSLELFPPRAGAAASQTWSALDRLLATAPDFVSVTYRPTFVLG
TRPAEPAVRVIREHNPAEDVVTHVLARSSTPLMAHLTCIGYRKRDVVEIVRLFLALGVRR
FLALRGDPPRGHDADELPGELAHAEDLVRVIREVEAEYFDDGERHLTIAVAAYPAVLDHG
RGVEILAAKQAAGADLAITQVFYDPEDYLSLARAATYCGVSMPLLPGILPMTDLARLSRL
AALTGVPIPAGLAASLGPARGAQTVARGIDATLRLATEVLDGGAPGIHLYTFNRTRPALD
VISQLRLGGILGGERVSASMQRDVRRAYLNATPGGDRRMPEPAHAGSARP
>A0A2T4DGD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marivirga lumbricoides|TrEMBL
MKVTEHIANAKKTVFSFEILPPLKGQNIKTLFSNIEPLMEFKPPFIDVTYHREEYVYRDK
GNGLLEKRTTRKRPGTVGICAAIKNRFDVDTVPHIICGGFSKEETENALIDLDFLGIDSV
LILRGDPIKSEAKFIPDPNGHAYAIDLLEQVVQMNKGRYVDEELKDATPTNFCMGVAGYP
EKHFEAPSMKSDIKILKKKVEAGADYVVTQMFFDNQKFFDFVETCRKEGINVPIIPGLKP
ITSLKQMTALPRTFYLDLPDELVDQLEKCKTNEEVKEIGIEWCIQQSKELINFGTPCLHY
YSMGKSDPIYRIAKQVF
>A0A2E3Y4W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIEFFEKANKTLFSYEIIPPFRGGSIDRVFDLVDQLIPFEPPFIDLTSRSAEVYLLDK
NNIATKRIRRKRPGTIGISAAIKNKYNIETVPHILCNGFSREETEDALIELNYLGIDNVL
AVRGDDLRKDLSPDNQKSKNNYASNLVDQINRMNNGEYIEDLIESSPSNFCIGVGGYPEK
HFEAVDMSTDIKYLKEKINLGADYIVTQMFYDNNVFFRFVDDCRSEGIDVPIIPGIKILS
LESHLKTIPENFYINIPKDLS
>A0A4Q6DQI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriaceae bacterium|TrEMBL
MKVIDHINQSTKPLVSFEILPPLKGKGIQSLYNHLDPLMEFKPAFINVTYHRSEHVFKKK
ADGTFEKVVVRKRPGTESICAAIMNKYNVDTVPHLICGGFGINETEDALINLNYLGIDNV
LVLRGDAAKNEAGFEPEPGGHKYALELLRQVSNLNSGVYLEEELKNTTKTKFCIGVAGYP
EKHFEAPNMDTDLQYLKQKVDAGADYIVTQMFFDNSKYFAFVNACRAIGIEVPIIPGLKP
IYTKKQLTVLPKIFHIDLPTDLSNEIVKCKDDEAVEQVGTEWLLMQSKELYKAGVPVLHY
YTLGRPNLVANVVRELV
>A0A5E7FSR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
NEVKIPAAPHMSCVGDSKGDLRSLLSQYKDAGITRIVALRGDLPSGMGMASGEMRHANDL
VSFIREETGNHFHIEVAAYPEMHPQARNFEEDLINFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQAFG
EQVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1T5H3M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. AC-3|TrEMBL
MGLLERLKTHVLTADGAIGTVLYGYGLEYCHEEMNIQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESRVQQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLEEI
LATVDEQATVLLAGNPDGLLLETYYDFEELTATLGMLRAKTKLPIIAQISMHEPGILQNG
MSLNNALHELEALGADLVGVNCRLGPHHTIQAFEVVELPKKAFMSAYPNASLLDVEDGRV
VYESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVEEKYAKPEKVEI
VREAEPANYEPLHVKVKRERSVIVELDTPRHLEIEGFIAGARKIYEAGADVVMMADNSLA
SPRISNVAMGALLKETHGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVSR
LEKKIEYGADYFISQPVYTKEKIVEIYDATKHLETPIYIGIMPVTSYKSAEFLHHEVPGI
KLSDDVLTRMKECGDDKERATLEGIAIAKELVEVAAEYFNGIYLITPFLRYDMTLELMKF
IEQLDEQKKGVSING
>A0A2A4H0B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus delphini|TrEMBL
MSRLLNALKNNILVADGAMGTILYSEGLDTCPEAYNLTHPDKVESIHRSYIQAGADVIQT
NTYGANFEKLQQFGLEHQVKAIHQAAVAIAKRAAGPDTFILGTVGGFRSTKQGELSLSAI
QYHTDIQVDTLVAEGVDGLLFETYYDDEELLNAIKQTRQKYDIPIIAQLTASNTHYLVNG
KEINSALQQLVKAGADIVGLNCHHGPHHMKRTFGHIELPNNAYLSCYPNASLLDIDQQTF
KYSDNAQYFGETAEQLIQEGVRLIGGCCGTTPDHIRKIKTAVQGLKPIQEKKVIPIHQKQ
TSEAPKPTRQNLATRVRERPTIIVELDTPKHLDTTKFFQNVKALDDAQIDAVTLADNSLA
TVRVSNIAAASLIKQQYSIEPLVHITCRDRNLIGLQSHLLGLSLIGVHEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGVNTDGDTLKVATQFNIAGGFDPHVSNIKAAVRK
METKIKSGMHYFITQPVFTKEKIVEIYEATKHLDVPIFIGIMPITSYKNALFLHHEVPGI
KMSDDVLAQFEAVADDRQATYELSLSLCKSLIDTVHTYFNGLYLITPFERIDYSLELAAY
SKSITTSHQEAIL
>A0A7C6IQY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronincola sp|TrEMBL
MKIIELFERKKLVYSFEIFPPKPTSPIERVYDTIEELSVLNPDYISVTYGAGGSVNNNRT
AHLTHLIKDTYDIESVAHLTCIGASKADIDDILNELQEKKVNNILALRGDLGKTGVGEFT
DSQMLKRHIRDNGNFGIAGACYPEGHLESNKDVDKDVWVMEKKEEAGAEFFISQLFFDNN
VFYDFLEKTEKQGIKGPIQAGIMPVVNKRQIERVVSLCGATLPKKFLRIMDKYEHDKLAL
RDAGIAFALEQIVDLASAGVRGIHLYTMNNPHIAKTITRNLDFILSSINREAK
>A0A6P0KXR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moorena sp. SIOASIH|TrEMBL
MTNPTKNSFRTAVESGEFLITAEVAPPKGGNPAHMVKMAQTLKDRVHAINITDGSRAVMR
MSSWAASVILRQQGIEPICQVACRDRNRIALQADLMGINALGISNILALTGDPVKAGDHP
DAKSVFDLESVRLLQLITKLNQGVDFNDKPLTDQGTDLFTGAAVDPQLKSWSGLQSRFER
KLDAGAQFFQSQLICDFDRLEKFMDQIAAGSNKPILAGIFLLKSAKNAKFINKNVPGVNI
PDEIIDRLAAADNQLQEGIKIAAEQVKLAQQLCQGVHMMAVRREDLIPQILDLAGISPLQ
KSSAVNDLVFK
>A0A176Z6Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium centrolobii|TrEMBL
MTDPTTPAQTDGQNGHLAKRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYGA
GGSTRERTHATITRILKETALLPAAHLTCVGASRSEIDEIVDRYHEVGVRHIVGLRGDPP
GGIGTPYSTHPDGYQTSAELVAGIKKRHADIEVSVSAYPEKHPEARDFDADIDTLKAKVD
AGATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRAGTSVPDW
LAEKFEGLDDDPDTRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRA
KSAQKAA
>A0A3S2VI11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. RMa-01|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWETVSKLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGVSIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIHEFHLYTMNRAPLVSAVLDNLGFSRRAAKSAGAAA
>M9R9R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Octadecabacter antarcticus 307|TrEMBL
MFVKLMNLLHVDQGRIKKQPLGDRHMTCPSVSFEFFPPKSLQASFRLWDCVQTLAPLDPS
FVSVTYGAGGTTRQLTHDAVDAIVKTTDLPVAGHLTCVDATRAETLAIAADYKAAGVTHI
VALRGDPPKGSGGFSPHLDGFQSSIELTGALADKGFDVTVGAYPESHPDAANQQACIDHL
KAKIDAGASRAITQFFFEADTFLRFRDACADAGITAPILPGILPIENWAGVQKFAAGCGT
AIPQILKDAFANAKDPDLINLLATAQATELCDHLLDEGVDHLHFYTLNKPELTRDICHAL
GMTPAVRLQNVA
>A0A521IPW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerochaeta sp|TrEMBL
MRVTEIIQASKKTLFTFELVPPLKGRTLEPLLETIRTLMEFDPSYINVTNHQAEVVYIER
EDGLLQRKTVRKRPGTTALAALIQHTFNVPTVAHLICGGMSREQIEDALIELHFLGIDNV
LALRGDPPAGEKRFIPMPEGHAYSSQLVGQIVDLNHGRYLDDQYRDGEATRFSIGVAGYP
EKHAEALNMTVDLANLKKKVDAGAQYIVTQMFFDNGKYFSFVNACRSIGITVPIIPGLKP
IASKRDLSLIPQTFGVDLPEALTSELEGVDSNAEITEIGVQWCIAQSKELYAAGVPSIHY
YTLGKARNVARIVRAVY
>A0A5C5YXL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium CA13|TrEMBL
MTLVSHYKSSRCAISFELFPPKTAAGMDALAKSIEQLNQFSPSYFTCTYGAGGSTRDTTL
DVVEKVKELTGLPVASHLTCVGSTVEQLESFLQDAASRSVDYIVALRGDPPQGSDQFEAV
EGGFRYANELVELIHDRFPQFSMAVAGYPEVHQEATSAKSDLENLKRKVDAGADIIITQL
FYNNDDFYRFRDACVAEGISVPIIPGILPVTNFKQAERIASMCKAEIPSTLAKTMSQNDD
PKYQFNVGVDHARNQTLNLIENQVEGIHYYVLNKSEAAAKLLNGLELAAG
>A0A1V4RUV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4484_190.2|TrEMBL
TCRDRNRMALQADLFFAASRGINNVLCLTGDSVILGDHKEAKGVFDLDSSQLLAAIRRLE
KGKDLGGNDVDGSVSFCAGAIVTPEANPLEPQLIKIEKKIEAGAEFIQTQAVYDLQTQAV
YDLDNFKQFMDYARQFPVKILAGIILLTSAPMARFMNKNVAGVIVPQELIDEMASAPKGR
AIDKGIEIAGRMIKRVRDEKMCDGVHIMAIGKEELVPDIMAAAGLD
>A0A2T4YTE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas aerolata|TrEMBL
MTTITIPQLAEARRALEEPLFADLAGDVGISFEFFPPKSEKMEAQLWDAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLARLHPFEISVAAYPECHPESGGHDVDLDNL
KRKLDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFASACGA
EIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPSEKVAAA
>A0A6P4CPR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arachis duranensis|TrEMBL
MKVIEKIRAAAAADPDRVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGS
TADLTLEIANKMQNMVCVETMMHLTCTNMPVEKIDHALQTIKSNGLQNVLALRGDPPHGQ
DKFVQIEGGFACARDLVKHIRAKYGDYFGITVAGYPEAHPDVIGSDGLATPEGYQNDLAY
LKSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCK
TKIPADIFAALEPIKDNEEAVKSYGIHLGTEMCKKILAHGIKTLHMYTLNMEKSALAILM
NLGLIEETKINRSLPWRRPANVFRVREDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSR
NPSYGALTDYQFMRPRARDKKLVEEWVVPLRSIEDIYERFKQYCLGKLRSNPWSELDGLQ
PETRIINEQLEKINLKGFLTINSQPAVNGEKSDSPTVGESKRCRRVYMNNFLTFFCSKEK
LDALVEKCKNRSSLTFMAVNKEGSWRSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFMV
WKDEAFEIWSRGWACLYPEGDASRKLVEEVGNSYFLVSLVDNDYVNGDLFAVFADF
>A0A364L307|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces amestolkiae|TrEMBL
MHVGQKLQEQAASGRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRS
ELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALEAAYHAGCTNILALRGDPPREQEK
WEAAEGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNSDVDQLIDHLKEKVDAGSTF
IVTQMFYDVDNFLNWVDKCRAKGINAAIIPGIMPISTYDAFMRRSNWTKIRIPPDWLEKL
EPVKADDAKVREIGTKLVAEMCRKLLGSGQIHHLHFYTMNLAQATRLILEELRLLPSEES
PLHKPLPWRRSLGLRRRSEDVRPIFWRNRNASYIARTADWDEYPNGRWTDARSPAFGELN
AYGVRLKGTNEQNIKLWGAPKSIKDLSEIFLRYLNGKLDRLPWSDQSVTLETSDIQNELL
DLNRRGFLTINSQPAVNGVKSNDPVHGWGPRNGFVYQKAYLELLVPPEHVDEILRRIEKN
PDLTYYCVNKTGELKARSDEGPNAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQLGDDW
AKCHPADSPSRKLLQRVMDEWYILNIVNNDFHKKDDIFRLFDGLVIKDFETEVVTTAPVV
TDGTN
>A0A5M6BZL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kwoniella shandongensis|TrEMBL
MSQLTSLISSRDVPFHTFEFFPPRTEAGLVNLLDRIRRLASEPLPAPLAVSVTWGAGGST
ADRSLELAEHVVKMGLDVVLHLTCTNMAKEKVDQALERCRALGIRNILALRGDPPRSEEY
AVSSDPTPDFFKHADDLVRYIRAEHADYFCIGVAGYPTPHSDSENEEDDLHWLKVKCDAG
ADFIITQLFYDVDGFLNWVKTCREKGISQPIIPGIMPIQNFASFRRLVNLTKCPVPDAIM
AELEPISSDDAAVKKYGAELATKMVSQILGSKLVPGVHFCTLNLEKSVRTILENLGWSSA
ASGGRSNSPAPRHNRLIEDDADMSNGNGSTGIAINGNSKLSPTTQLKALSISPSEASQLA
QWGLTHNTLPPTPKAGLGGKGASTGATTEDSWDEYPNGRFTDVRSPAYGEIDGWGSGLKI
TAAQALKEWGTPTDASQLSSLFTSYLQSSPQTPTTPFCDLPLSPESATILPHLVALNSSK
LQHWTVGSQPAVDAAKSDDPIHGWGPRGGYVFQKAFVEFFVREEEVNRLEEKLKKGDSQI
TMYAGNKQGDFKTNALKDAVNAVTWGVFPGQEISQSTIIEETSFHAWKEEAFDIWTEWSL
LYPRQSPARKLLEGIAGEWWLVSLIHHDYKDAEGLWKFLLE
>G6YWG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter manganoxydans MnI7-9|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYREHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDRESIRK
FGEEVVTEMCEKLLAAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A563VQ89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyella patelloides LEGE 07179|TrEMBL
MTSRLRNAVTNQEFLITAEVAPPKGSNPTRMLKVAQKLKNRVHAVNITDGSRAVLRMSSL
AASVILLNNGIEPVCQVACRDRNVIGLQADLMGASALGITNILALTGDPVKAGDHKKAKA
VFELESVRLLRLINKLNQGIDFNDKKLPDEPLNLFAGAAVDPQLKSWSGLQKRFERKIEA
GAQFFQSQMITDFDKLDKFMAQIASVGNKPILAGIFLLKSAKNAQFINKYVPGVDIPQST
IDRLAQATDPLQEGIAIAAEQVKTAKTLCQGVHLMAVKKEELIPEILDLAGIEAIDD
>A0A3D8J644|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter aurati|TrEMBL
MENSDFIEQFVDKLCNKKCITYEICPDKSASIMPIITKIQSAGLDKGIIDGFVCTDSPLA
RLKLHSGMASIRLQQALQKPLICTISMRDRNSLALSAELLGLNDFDIRIFLALSGDPLKL
GDQPQAKAVFEGNSLRILELIAALNQGLDLNAGALQSAVKRIYGFSVINSYAKKMELLRK
KMESKICANALGLFTQPIYDIEVAKLLHEWLHSLNYQHNKRCVLMQGFFPITSFKRALFL
HQKIPDVFVPQLWLETLEKASLKGTQYEKQKGMEMSIKLFAQLYGYSPKIHFMNHNAVKN
AKTILNSIQ
>B3NGU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila erecta|TrEMBL
MHAIQVPAGGALPAAASYIPCVTFAPGQNECAVAEQRIGTLVAERTAQRRFFYGIEVMAS
GAGGRPTCLDFNHFLPLLPTFVSVVWLSQRYWDVEPVGQVESLRLAQHLATRIPVLPHVS
AYRMRRQRLDQLLALNFSSLLAVRGDHVHEEQDFLVGHPMVEHLRRRRGDKISVCVPGYP
EGYTSLGDVPQNSTKNMAFLKAKVDAGADCIITQLCYRPEVIVQFVKDCRAAGISVPIVV
GLMSHESFRSYSMIEQIAGVHLPDDLREELDQLHSAHMRDMKSDQDLIRRFFVSLTVRTV
RHVLEADVGVWAFHFFTLNRFKSVQAVLQELRDLDVIKDSERDKKGYEE
>A0A0U3RYR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii XBB1|TrEMBL
MSLLAQYFAQQQFCVLVEYLSSHQAQWPVKAQFAGFPAAMTLADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDAKTRGQKNLLLLTGDKLKQHCYSHDLEPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMAAL
QDAHAFLARHQYAQKMLACVMPLTLARAKFMLKHNVAGIVITPHMLQVLQQEKEQGLSDR
VYVRCALQILMCRHLGFAGVHLSACHQPEEQVLLESYIEEYRHLSFAECEQLWNTLWQVQ
TSTEFHPKLAYYSRPATSSQIIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDRTKANN
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTAILKEKLIPTVSIAVRGTSSWKNWYVEAAG
>A0A7W8HJF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Quisquiliibacterium transsilvanicum|TrEMBL
MTPNVSFEFFPPNTPEGAVKLRATRAALAEAAPEFFSVTYGAGGATRDKTLAVVEEIAAE
GRAVAPHLSCIGATRESLRELLELYRGHGIRRLVALRGDLPSGMVDHGDFRYASELVEFV
RAETGDWFRIEVAAYPEMHPQARTPAEDLQAFVAKVRAGADSAITQYFFNADAFFRFRDD
ALAAGVDVPIVPGIMPITNFTQLARFSESCGAELPRWVRVRLASFGDDREAIRAFGFEVV
ADLCRRLVAGGVPALHFYTLNQAQPSLDLWQAAR
>A0A8H9TXQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter farmeri|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPAGSGKPDMYAADLVSLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFN
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A7Y2Q204|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium ulmi|TrEMBL
MSTAASTSPTASAVPFSFEIHPPRTDAGLPALCETIGHLAAARPQFISVTFGAGGSTGGR
SLEVLTHILRETDVPPLAHLTCVGNRYEGATALIREFLDAGIESFLALRGDPPAGVDEDD
VDLGDLESAAHLVQLIHRVQAERAPYTEAAIPGVPGAARLGRPRKAEIAVAAFPNGHPRS
RHPREDIDALLAKQAAGATFAITQLFFHADDYLGFVCRARDAGVTIPILPGIMPITSPAR
LRRVLELSGEELPVELSVALEVEPTGEGRREVGVAHAAALARDVLAGGAPGIHLYAFNNH
ETVLATLREAGVLIDHDCKEPVR
>A0A8I0PDX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces stelliscabiei|TrEMBL
MGSAGLRTLLDGVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLTARLAAH
GRRVVPHVPARLLRDDAHLKDVVDRLREAGVEDVFVPAGDADPPAGAYDGALPVLRRLSE
LGAPFARVGVTGYPESHPLIHDDITVQAMWDKREHATYVVSNLCFDPRVLGEWIARIRGR
GIALPVHVGVAGPVQRAKLLAMATKIGVGESTRFLTKHPSWFLRFATPGGYAPEKLLTRT
EQTLTARASGVAGLHLFTFNQIAETEAWRRALLERLGG
>A0A2N0MNH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium MP-NPac-SRR3961935-G1|TrEMBL
MKIKDILTKTRPISFEFFPPRSAEGIPAVLETMDELKAYCPDFVSVTYGAGGSTRAFTEE
ITLQIKNETGVEVMAHLTCVGQNKEEIDEVLQRLESEGVDNLIALRGDPPKGTTEFVPVE
GGFQHASDLLKYVKSNFKFGVAAACYPEGHTESVDLDTDLKYVKMKVDEGADFLVTQLFY
DNRYYFDFVERARAGGIDVPIIPGILPVLNSAQVRRFTALSGSEIPPDLDKLLDKYAESD
NSARDMGVEYATAQVRELWDSGVPGVHFYVLNRSYSVSRILDNLTISGHQRQD
>A0A1I1ZP51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteribacillus iranensis|TrEMBL
MNILSELNERILVGDGAIGTFLYEQGYKESFEAMNLTSPDIIQSVHEQYVQAGADIIQSN
TYAANRIKLEKYGLEDKVSLINREGVKIAKQAARPGTFVLATIGGVRGVQRLDMTESDIR
EALEEQATALLEENPDGIMLETFYDVKEAEATVEMVRSLTTLPIIAQLALGEIGVMHGGT
PVTEAFDTLEKAGADVVGVNCRMGPYHIIRSLEGVSLNEQRVLSAYPNASMPAFDDGRVI
FQSNPDYFYEKAKELREQGVRLIGGCCGTTPEHIHAISRAVKGSSPLKKKAVVTEHPPEK
EATNGSSLTRLDDLVKQEPTVIVELDPPKKLGTDRFLEGAKKLHESGAAAVTMADNSLAS
PRVDNVAMGALMKTKTQARPLLHVNCRDRNLIGLQSHLLGIHALGIQDILAITGDPTKVG
DFPGAASVYDVNSFHLISLLKEMNEGRSFSGKSLGEKTSFTVAAAFNPNVRNLDRAVKRL
EKKIAYGADYFITQPVYGKEQFKEIYESVKHLSVPVYIGIMPLVSGRNAEFLHNEVPGIT
LTDEVRRRMAECGEDRDRAKQEGIAIAKSLIDEAIKYFKGIYLITPFLHYDTTAELTSYI
RQATNTINQ
>K9PZS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. PCC 7376|TrEMBL
MTTCLRRAIENQEFVITAEVAPPKGGNPQHMVDMASLLKEKVHGVNVTDGSRAVMRMSSI
AASTVLLQNGIEPIFQMACRDRNVIGLQADLMGAYALGLRNMLALTGDPVKAGDHPKARP
VFDLESVRLLKLITKLNGGKDFNDKKLPDGALDLFAGAAVDPQLKSWYSIESRFAKKVES
GARFFQSQMITDFIRLEEFMSRVASQHNVPVLAGIFLLKSAKNAKFINRCVPGAQIPDSI
IERLEYADQPLEEGIKIAAEQVKIAKDLCQGVHLMAVKREDLIPKVLELAEISIKTDKPV
LVS
>A0A1G0E8E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium GWE2_42_36|TrEMBL
MISSPINLSFEFFPPQDVEGLEKLLSVAKKLSALNPEFFSVTYGAGGSTRDNTKQTVQAL
RDHFDVPVAPHLSCIGSTRETITRILDEYIEMGIKKIVALRGDLPSGMRNPGDFSYASDL
VTFIREHSGDHFEIKVAAYPEFHPESKSSSEDLSHFKGKIEAGAQAAITQFFFNTEAYLH
FVEDCRAMGVAVPIIAGIMPISNWERLMKFSRTCGMDLPIWLKSRMDALGTDEMARRNLS
IKLLSHLCRRLQQAGVTDFHFYTLNQSKLSLAICESLLRVQRDE
>H1FVZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurimonas gotlandica (strain DSM 19862 / JCM 16533 / GD1)|TrEMBL
MFDKLINKLKNDTYITLETTPGHSPVFSPIIDKIEELELQNYVDGFSTTDNPLAKLKYNS
LFAAKMLQDRFNKPVIATMSMRDRNKIALQSDLLGANEVDIRAILALTGDPATISDQPHA
KGVFEADSSLLLDIISAFNSGMDYAGKPLAFKPREIYPFAVVNSYAKNPKTLQKKMQKKI
KHGAIGIITQPVYDLENAKQLLELKEAANREFGSENKSAELILGIFPITKLRTAQFLSAH
VPGINVPDSWIEALRIANEKGVEEEYKVGFELSKNLFDSLKAYHPKIHLMTANQFTLAKD
ILK
>A0A3N1WZV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp. BIGb0124|TrEMBL
MQGAPRPEAARVPVAGPGAGEPTDPQRNTSNRKAGMVSGPTRKDSMTTLPISLEFFPPKT
AEGADKLRLVRQQLYGLGPEFCSVTYGAGGSTQQGTFDTVSQILAEGVDAASHFSCIGAT
RASVAEQLGQLKRMGVSRLVALRGDLPSGYGTGGEFQYASDLVAFIRETTGDDFHIEVAC
YPETHPQARSPEHDLQALAAKVKAGADSAITQYFYNADAYFRLVDDARRLGLDVPLVPGI
MPIASSSQLMRFSDACGAEIPRWIRLRLQSYGDDVASIRAFGLDVVADLCERLRAGGVPS
LHFYTMNQSATMLSLCERLGLGPVKA
>A0A0B5RTZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myroides profundi|TrEMBL
MKVTEHIQKANGKTQFSFEILPPLKGQNIQGIFDSIEPLMEFDPPFIDVTYHREEYEYKE
AGNGLWEKRTVRKRPGTVGICSAIQNRFKLDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKNETYFKPEPKGNKYASDLVTQISELNQGIYLDPELENTSKTDFCVGVAGY
PEKHMEAPNFDTDLKYLKQKIDNGAEYIVTQMFFDNSKFFAFVDKCRAIGIDVPIIPGLK
PLATLSQLNLLPQRFKVDLPDDLVTEVLKAKDNAAIREIGIEWCAQQSRELIEAGTPIVH
YYSMGKSDNIKNIIKLATV
>A0A375AGA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya aquatica|TrEMBL
MSFFHANHQEALNQNLAELQGRINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDATREELKAIAQDYWSSGIRHIVALRGD
LPPGGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAISA
>A0A2V5IK95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter psychrolactophilus|TrEMBL
MSEDTVAANAGREELPTRVEIIPTAGIVDAAVSELPAASTLTVTCLPHHGIERTMAASLE
LAGHGFDVVPHLAARSIGSREQLASLLRDCHAAGIAEVFAIGGDKAQTAGPYDSSESLIR
DIAEISGGALRIGVAGYPEGHPAISQQQLLDSLRSKAEFADRIVTQMCFSAELIERYISM
LRSEGITLPVWAGVAGSVPRTKLISLATKIGVGSSLRFISGKGALGLRLLGGTHYRPEEL
TADLSVLGTPPAGIHLYSFNNLRNFAPSPA
>A0A0K0XSW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wenzhouxiangella marina|TrEMBL
MSTPSPQHSFEFFPPRDDDARADFLVARDRLARLGPAYMSVTFGAGGSTRSRTRDTVLAI
HSETGVPAAPHISCMAEDHDSLHELLDSYRGAGIRRLVVLRGDRPSGGGSGVMDHAIDLV
RFIRRHYGDHFHLEVACYPEHHPESPTPESDLRHFRAKVEAGANGAITQYFFNADAYFRF
LDEAQRVGVDVPIVPGIMPITNYARLARFSNLCGAELPLWIAKRLQAWESDGDRESIRAF
GEEVVTQLCRRLLEGGAPGLHFYTLNRAAPTLALCRNLGLGPSA
>A0A2S5C4X6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lelliottia sp. 7254-16|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0P1E9T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria atlantica|TrEMBL
MTKPEISFEFFPPKTLEASFRLWDTVQTLAPLEPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLPVAAHLTCVDASRQETLEIADTFVRAGVQDIVALRGDPPSGQDRFEPHPEGFANSV
ELISALAETEMFNIRVGAYPDIHPEAQNAGTDIDWLKAKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDKLIVPGILPIENWKGARNFAKRCGTRIPQWVEQAFEKAVRDDREDLLAT
ALCTELCSDLIDGGVDKLHFYTLNRPELTRDVCFALGITPKADLQNVA
>B7N2T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O81 (strain ED1a)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A191Z1M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas silesiensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLKQYKAAGITRIVALRGDLPSGMGMASGELRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLANFVRKANAGADSAITQYFFNADSYFY
FVERVRALGVDIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTASIQRFG
EQVITEMCERLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A2N3CMN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HGW-Alphaproteobacteria-2|TrEMBL
MTPQISFEFYPPKTLDASFRLWEAVQLLAPLAPAFVSVTYGAGGTTRRLTHEAVEAIHRN
TGLAVAAHLTCVDASREETLEIARSYAAMGVKQIVALRGDPPKGSGRFVARHDGFASSVQ
LVAALKAAGDFHIRVGAYPDPHPESGGDPQADIDWLKRKFDAGADEAITQFFFEAETFLR
FRDRAAAAGIDPGRIIPGILPVEDWRKARRFAEGCGARVPADLDAAFARAIRDGREELLA
IAHCSELCADLMAEGVGKLHFYTLNKPHLTRDICAALGVSQKAELSRVA
>A0A354BUQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSGIKPARRWQPAFYPFKREKLSRRVLAKTELLVKGPLFGCRMCGNCLLQETAFICPMEC
PKGMRNGPCGGVTPENNCYIDETRKCVWYAIYKRALKTGRQEMLLEVLPPLDWDKAGTET
WGEVARQVKKVGTEKFVNSLFTVDKKKKSEVWDSVFRTIRQPDWWKGDSEYHPPLDAEPA
SRLARELKEGKFVIATEVTPPLGASTGKLTRDIESVMPYVTAINFTDSSSARPKMSSIAC
SCIAIKLGAEPVLQITARDTTRSGLQGDIVGLNGMGIYNVLCISGDSPIIGPTPVSSMNF
PDIDSVQMLWILRRMRDEGIYLDGRRMKESPKLFLGAATSPFASDPELQAIKDTKKVNAG
AQFFQTNLIFEPDRLDPWLEQLYKRNILDKVYIMIGIAPLKGYKVAEYLHRRVPGVRLPE
SILNRMQKAGEGAPEEGVQITLELIESIKKKQGVNGIHIMTLGWESVVKRIVNESGLHQT
>A0A3P3QZH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoanaerobaculum gingivalis|TrEMBL
MENIRDYLKNNVLLFDGAMGTYYDELTDDGIGCELANIKNPELIKGIHNEYIEAGAKAIL
TNTFSTGIDAFSGDRELQKKVIVAGIDIALEVAKSRAYVFADMASINADSNSAAFEEYKI
IADIFLEKGINNFYFETRNSTIGLKAIGEYIKEKSPEAFITASFAVMPDGYSSEGYYYKT
MFKEICESGFFDGVGLNCVSGANHMAKLLKDVDTEGLYLAAMPNAGYPIVRDNKIYYGSL
ANYFAAQIEDILDMGVNVVGGCCGTTPKHIELLKKSMSGMLIKPRKSVKKEKNISQKIRL
NRFEQKLISGQKPIAVELDSPIDTNIAKFMDNAAKLKSAGADIVTIADNPIARARMDSCL
LACKVRNELDFDVLPHMTCRDRNVNAAKGLLLGASAMGVDNVLVITGDPIPNAQRDEIRS
VFEFNSVKFANFIKSLNDEVFESPMNICGALNVNAKNFSAELRKAKRKQENGVKVLFTQP
VLTQRAIDNLKEARENLDVKIMGGIIPIVSERNARYMQSEVNGIYITDDIVEKYIGKERE
EAEEIALSMSKEIANEIYDLVDGYYLITVLNRVNLMERLIKTVKEVCENK
>A0A8H4PGD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium albosuccineum|TrEMBL
MHIKEMLTDAERSDQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLRAYKAGCTNILALRGDPPRDQDT
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGCDDNKNEEELLDHLKEKIDMGASF
IVTQMFYDADNFIRWVKKVRERGINAPILPGIMPIATYASFLRRANHMQAKVPQAWLDAL
EPVKNDDVAVRNIGKSLVADMCRKLLANGIHHLHFYTMNLAQATRMVLEELNWAPSAERP
LQQALPWKQSKGLGRRDEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTVQDIAQLFVRYLRNEIDSLPWSESPLTTEADEIRDDLVE
LNKRGLLTVNSQPAVNGVKSSHPIHGWGPSNGYVYQKSYLELLVHPDVFNDMIGRIEKHP
DLTFYAVTKDGELRSNAPSDCPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDAASPSRALIEEVMNDWYLVNIVNNDFHQNGTIFELLKGLEVKDLTTPATPKSEAA
TNGAAVSEPVANGTAAAAAAN
>A0A1L3J9R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingorhabdus lutea|TrEMBL
MSHSISHSQLQESRLAIDTPLFAGLPGDVEISFEFFPPKSEKMEQQLWDSIMTLAPLQPR
FVSVTYGAGGSTRERTHATVARIAAETEIAAAAHLTCVGASKEEIIETAQQYWDAGVRHI
VALRGDAPDGEQFVLHPQGFASAVDLVAGLKKIAPFEISVAAYPETHPAANCPQSDIDNL
KRKIDAGASRAITQFFFDAEHFFRFRDSCAAAGIDAELVPGILPVSNVGQTRKFAGMCGA
AIPNWMDDLFEGLDDHPASRQLVAATIAAEMCRKLYAGGVRHFHFYTLNRAELSFAICHL
LGKRANIEGEIA
>A0A7X6PC23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSVIEKIKNAKGPLFTFELLPPLKGHSIERIYSAIDRLMEFEPAYINFTSHRNETIYRER
SDGFLEKRVTRLRPGTIALAAAVKYKYNITVVPHILCGGFTREETENALIEMNFLNIDDV
LALRGDPQKGSRVFIPGKDGHRYSSELVAQIVDMNNGKYLEDTLREKTPARFCIGVAGYP
EKHSEAPNMETDIVNLRKKIDAGAQYIVTQMFFDNEKYFRFRDMCRDADIDVPVIPGIKP
VSALNDIKMLPQTFHIDLPGDLVKEIEKCTTDQEAREAGIEWAIMQSRELIGKGVPGIHY
YTLGRSDNIARIVKASF
>A0A7Y8LHS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bryobacteraceae bacterium|TrEMBL
MNTTSTERVSRAAEFRELISRRAVVADGAMGTMLYGRGIFINRCFDELNLSMPQLVKDVH
HEYVRAGAEIIETNTYGANRIRLATFGYADQVDAINRAGVRLAREAASERSDVFVAGAVG
PLGVHIEPLGPTSFAEARQAFREQLLTLNEAGVDLLIFETFSNLSELREALEAAREVAGS
EMVVVAQITIDDDGNLHDGTRPETYGPWLDACAADVVGINCSVGPKATLETLEKLMRFTS
KPTSAMPNAGHPTKVEGRNIYLSSPEYLAQYARRMLWAGVKIVGGCCGTTPEHIKSIKSE
ARSLQPGVQRLQVTIEEPAAKSKKMDKVPVAEKSELGAKIAAGKFVVFVEILPPRGVNAE
REIAGARLCKDHGIDAINVPDGPRASARMSAQVTCQLMQREARIETVLHFCCRDRNILGI
QSELLGAHAAGIRNLICITGDPPRMGSYPDATAVFDVDAIGLANIVTNLNHGLDIGGNPM
GSQTALLLGVGANPGALNFEEEIRRTAWKVEAGAEYIVTQPVFDLKQLEQFLKRIAAFRI
PVITGIWPLTSLRNAEFMVNELRVPVPGEFMERMRKADDPDKARAEGVRIAQEMVQRVRP
MVEGVQLSAPFGRYQMAIEVAEAVGPR
>B4HED5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila sechellia|TrEMBL
MHAIQVPAGGSSPAAASYIPCVTFAPDQNETAVTEQRIGTLVAERTAQRRLFYGIEVMAS
GPSGRPTCLDFNHFLPLLPTFVSIVWLSQRYWDVEPVGQVESLQLAQHLASRIPVLPHVS
AYRMSRQRLDQILDLNFSSLLAVRGDQVHKDQDFSISYPMVEQSRRQRGEKISVCVGGYP
EGYTSLGDMPQNSAKNMEFLKAKIDAGADCIITQLCYRPEVIVQFVKDCRAAGIAVPIVV
GLMSHESFRSYSMIEQIAGVHLPDDLREQLDQLHSAHMKDMKSDQDLIRRFFVSLTVRTV
RHVLDADVGVWGFHFFTLNRFKSVQAVLQELRDLDLFKDAEKDTKGSEK
>A0A7X7EWG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MEKTTVIDLIRNSEKPLFTFELLPPLKGHSIERIYRTIESLLEYEPAYINFTSHRNEEVL
MERPDGLLERRVTRKRPGTIALAAAVKYKYNVNVVPHILCGGFTREETENALIEMNFLGI
NDVLALRGDPPRGSRVFIPNTGGHRNTNELVQQITDMNQGRYLDPDLKNSSATSFCIGVA
AYPEKHFEAPNMTSDMASLKRKVDAGASYIVTQMFFDNAKFYAFRDAIRAMGITVPLIPG
IKPVSAMTDVNLLPQTFHIDMPEQLVHELSKCRTDEDAREVGIEWTAAQSRDLLKNEVPG
IHYYTLGRSDNIARIVKASF
>A0A5D2TMV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium mustelinum|TrEMBL
MKVIDKIQSFSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DALVKNCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGAFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A1E9IAT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC075F09|TrEMBL
MTTVHPALSFELFPPRSHASCESLLHTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSNAE
LHRIGVDYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQPLSELEF
A
>A0A395L9M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. M14|TrEMBL
MTAQTLYPAERGNLRLSFEYFPPKTDEMEAQLFQTAEELSVFCPAFVTVTYGAGGSTKTR
SLTTVKRMIEEKGFANTAAHLTCVGAPKSEVDTVIDEFLAFGVRHFVALRGDPQGGIGST
YAPFPGGYESSSDLVRALRDRGDVEISVSSYPEKHPESPDVDADIDMLKRKVDAGATRAL
TQFFFDNDDFERYLERVRRAGIEIPIVPGILPINNLSQVQKFAGLCGASVPEVIVTRLAH
LEDQPTERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLITAVCDLVGFERADEMAQD
EQVALKAVAGAAA
>A0A2N2EWZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium HGW-Elusimicrobia-2|TrEMBL
MSGKGKFEGDDQMRIAEKLAASARGVSFECFPPKTEKGRKNLYCALAELEKYRPLFVSVT
YGAGGGNKDTAVGTVLSLKKDFSFEVMPHLTCIGAPVGEINRILDTYKAAGIENILALRG
DPPAALESFDESEGIFPHASDFIKHIRKEYGFSCGAAVYPEGHFQSASLEDDILHSAEKF
SSGADFGVSQMFFDNSYYYDFLDRLDKAGIKTPVLPGIMPILNFEKIRELAASSAKVTIP
AKLEQIMGRYSDPDDIRKAGIDYASLQCADLLKNGVKFFHFFMMNRSESAARIIENAGIL
>A0A316U3T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomicrostroma glucosiphilum|TrEMBL
MMMATDDWRITSKIAQAEREGRTWWSFEYFPPRTSQGLSNLFDRVGRMSDLGPAFVDVTM
HAGGRTLDLTNDLVKIIQTYLGVETCMHLTCTNMPREKIDRALELAKEAGCRNILALRGD
PPAGQHEWTPDAAGFTYARELVEYIKKNYGDYFSIAVAGFPEGHPESKDGRELEIERLKD
KLDAGADFIFTQMFYNYDIFANWVKEVRAAGITCPIVPGVMPIQTYGGYQRATERFGTLV
PQYFHDALDPIKDDDQKVREVGTQLVGDMCKKIIDPKNGLGVSGLHIYTMNLERGSRMLL
EYLDLAPTPQQVKTLPWTPSLTPKRREEGIRPIFWANRARSYVSRTETWDEFPNGRWGDA
RSPAFGDFDAYGVKLRYTNEEAKKLWGEPESLEQVKNLFRSFCNGEVKALPWSDSGVAKE
TTVINRQLGLLNALGYLTINSQPAVDGVRSEDEVHGWGPKGGYVYQKAYLEFFISPKQLN
KLVAQIEADPQITYHAVNARGDMRTNTTSEAPNAVTWGCFPHKEIVQPTIVESISFLAWK
DEAYEIGRNWSRIYDEGSTSRKMLEKIFGDASDEADDDSGWFLVNVVHNDFKSPEAIFKP
FLAAADPSTLQSLAKGTLSDAVTGLVDGVKGYGQAIAETLDGVKSAVLNGSTEGKQVNGA
NGASRITVDR
>A0A3D4WCF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
IINANPTNFCIGVAGYPEKHAESPNMAADIVHLKEKVDAGADYIVTQMFFDNADFFRFEK
ACREAGITVPIIPGIKPLSLKSQLSALPRTFSIDLPEALVREAEKCVSNQQVRQLGVEWA
IIQSRELIRHGVPVLHFYSMGKSDNIRAIAKEVF
>F6AFY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fulva (strain 12-X)|TrEMBL
MSQKRPTVSFEFFPTKTDAGHEKLLNTARELAGYNPDFFSCTYGAGGSTRDRTLNTVLQL
DSEVKVPTAPHLSCVGDSKAELIELLNLYKSKGINRIVALRGDLPSGMGLSSGELRHAND
LVELIRAETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADCYF
YFVERIRKLGVDIPVIPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDSQSIQRF
GEEMITGLCERLIEGGAPGLHFYTLNQAAPSLAVWKNLQG
>A0A316MTA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVTDLIKANGKTGFSFEVLPPLKGKGISQLFRNIDILKEFKPLYINITTHRSEMVYKNT
PDGLYQKVSERSRPGTVAVAAAIQQKYGIPAVPHIICSGFSRIETEYALIDLNFLGITNL
LILRGDKAKHENRFIPNDNGYSHATELQLQINEFNRGYFIDGTKMDIVTGEPFSYGVAGY
PEKHEEAPNIDIDIQYARQKVDNGAEYIVTQMFFDNKKYYDFVDRCRRAGINVPIIAGLK
PITTMSQLNLLPKVFHVDLPMELATELMKCHTDAEAKQVGVEWCRMQAADLIAHNIPSIH
FYSLNATRSVEQVARDVY
>M7PJI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga lonarensis MPL|TrEMBL
MSKPVISCEFFPPKTEKGVNTLQQVQQALAVLKPAFYSVTFGAGGSTQDNTSDAVIAIQQ
QASTTGIDAAPHLSCVGSSRERIQAMLQTYISHDIRRIVALRGDLPSGMRDPGDFRYANE
LVEFIRAETGDHFTIEVAAYPEVHPQAMNADIDLENFKRKVDAGADSAITQYFYNIDAYL
YFVERCEKAGIDIPIIPGIMPINNYAQLARFSAACGAEIPRWLRKRLEAFYDDTASMQAF
TLDFLTDFTDQLLHQKVPGLHFYTMNKIEPTLTICQRLKLTG
>L7J0Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnaporthe oryzae (strain P131)|TrEMBL
MDKITDKIAALPPDASYFSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
AQKSLELAEICQRELALTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRPGE
YAIPDDSEGDVNEFTWAIDLVRYIKLNHGDYFCVGVAAYPEGHAEESHPTNQSLEHDLPY
LVEKTQAGADFIITQLFFDISAYEKFEKTLREHPSGAFKDIPIIPGLMPIQNYQMIKRTT
KLSHAKIPDPLMARLDAVKKDDEQVKKVGVDIISELVDQVKEVKNRSSGPKGFHFYTLNL
EKAVSFIVERTNLIPATTPDDDEVAVVDDVALPSIHLNGATPAKDHLSVSSLHPPTHTNS
RRPSTIGSDPRNRVIVSSGRPASHPDYEATGFEASVPAQAINSRANTLAISEGEGVLGRE
ATWDDYPNGRWGDARSPAYGEIDGYGVSLHMSGTQAVQLWGRPATVEDVSNIFMRHLRGA
LPAIPWSEEEFNAETETIRDTLLALNSRGWWTVASQPAVNGLRSNDRTFGWGPQNGFVFQ
KAFVEMFLPSKDWKALREKLLSEKDVVCFYASNAKGDFESSDGGGDAPDGAPTGNGFADE
QPLPSGSSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWAEWAKVYGKDSPSEKL
LESLRADLWLVNIIHHDYIEKEALWDLLLK
>A0A6H0WGR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus tequilensis|TrEMBL
MGLLEDLQKKVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETGLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARVIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTQAKEFIS
VQHERAEPGLNEIAAEKRSIIVELDPPKKLSFDKFLSAAAELKEAGVDALTLADNSLATP
RISNVACGALVKQQLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNISLH
>A0A2S1SNR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces tirandamycinicus|TrEMBL
MALGTASTRTDRARTVRELLATDKTSYSFEFWAPKTEKGERNLWNALRRVEAVQPSFVSV
TYGAGGSTRAGTVKATQQIAADTTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPDGVRYAAELVRLIKESGDFCVGVAAFPEMHPRSRDREADIGHFVD
KCRAGADYAITQMFFHVEDYLRLRDSVADAGCETPIIPEIMPVTSVKQIERFARLSNASF
PAALEERIRAVADDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHQQS
>A0A7Y6RG50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas maris|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARKPRFFSVTYGAGGSTQARTREVVR
AVSESGITTAPHLSCIGSEKAQLRDLLAQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAIAAF
GTDVVSRLCQRLLDGGAPGLHFYTLNQAAPVLKVVDNLTD
>A0A836TPT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sneathiellales bacterium|TrEMBL
HMTKTSPPPVSFEFFPPKSSEMEAKLWRSLTRLAPLDPQFVSVTYGAGGTTRERTHATVK
RVVDETPIPPAAHLTCVGASKHEVNRVALAYWDAGIRHIVALRGDPPPGEGSFTPHPDGY
QNAAELVSGLAELRNFEISVGCHPEVHPDAMSAESDLDNLKSKIDAGACRAITQFF
>A0A6I3IQ13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. zg-36|TrEMBL
MVHTPSLSFEVFPPNPAAGNEKILSALQDMQGLAPHFISVTASNNTFNIEETTVRLTDYI
QNDLGIPSIAHLPAIYLTKKQVTTILAALDQIGVHKILALRGDILPDVTPQKDFQYATDL
ISFIKEEAPHFDIIGACYPEVHPDSPNQLSDIKHLKKKVDAGCSTLVTQLFFDNDVFYDF
QEKCHLADIDVPILAGIMPIINRNQALRLLNTCENIRLPRKFRAILDKYEHDPESLKAAG
LAYAIDQIVDLVTHDVAGIHLYTMNNPYVAKHIYRATYSLFKHSPLIAKA
>A0A520A824|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
VLVLRGDARHADASFIPTPGGHAYATDLLAQVQDMNHGKYLHEDHAAFKTDFCIGVAGYP
EKHFESPNLKTDFKFLKKKIEMGAEFIVTQMFFDVSKYTEFVQLCRDNDINVPIIPGLKP
ITSSKQLISLPKIFHIDLPEELSEAVQACMNEEAVKEVGIEWMIQQCKDLMKAGAPVLHF
YTMSNPEPTKKIAKAIF
>A0A015XCL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides fragilis str. J-143-4|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYQDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTQEETEYVLLDLQFLGITDL
LVLRGDKAKHETVFTPEGDGHHHALDLQQQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDMDIYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEKVHQAGIDIPIIPGIKP
FKKISQLNMVPKTFKVDLPEELTKEALKCQTDEEARQVGIEWCISQCKELMAAGVPSIHF
YSIGAVDSIKEVAKAIY
>A0A372MK06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerochaeta halotolerans|TrEMBL
MQVIDILNEAKKPLFTFELVPPLKGGDVQTLLESVRTLSEFDPAYINVTNHQQEVVYVER
EDGLLERRTVHKRPGTVALSALIQYTFQIPVVAHLICGGMDADQLENALVELNFLGIENI
LALRGDPPSGVKRFVPVKGGYDHSSDLVTQIARLNEGIYLDDQLQNAQKTHFCIGVAGYP
EKHGEAPNLTHDIQMLKKKVDSGAQYIVTQMFFDNSVYYRFVEACRNEGITVPIIPGIKP
IGSKRDLATIPQTFHVDFPDELVSLLNGATKLSEIREIGEYWCIKQAKDLIAHDVPGVHF
YTLGKADRVARIVREVF
>A0A1M5DRL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium fluvii|TrEMBL
MKVTQHIENAKGKPLFSFEIVPPQKGTNINDLYVNIDPLMEFKPPFIDVTTSREEYVYIE
KDGLFDRRITRMRPGTVGICASIQHKYGVDAIPHVLCGGFTKEETEYLLVDCQYLGIENL
VALRGDPMKGEKYFEPTKGGNAYAVDLVKQIKAMNAGQFLHDVLPMQNAPDFCVGVAGYP
EKHIEAPSLEADLKRLKEKVDAGADYIVTQMFFDNQRYFKFVEAARAIGITVPIIPGIKP
VAVKRHLQLLPQVFWLDMPQDLIHSIEQAKDNAAVRQIGVEFAVQQSKELIEFGVPCVHY
YSMGKSDNIYNIAKKVF
>A0A2T3LNY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium sp. GB-1|TrEMBL
MSDQYQPTPESELRVRYNDITRGVYFIGTTPPKTSTPIEDVEGIADRLVDRIRDLAIDGL
IVYDIQDEASRTNKPRPFPFKSTHDPRHYSSLLNKKTDRPVITYKSVVQSETEAFDEWLN
EAWDEYRVRDMVLVGSPSAKNDVSLPLSTAYQTLAENRNDFFTGGIMIAERHAKKGNEHE
RLIEKYKQGCNFFISQAIYDTQATIDILTRYAIECKEQGLKPQRIILTFSPCGSAKTLEF
IEWLGVSVPEATSLRILNAENPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRKE
EIDGSILLYKLLRSSMDSHLAKHEFRLLKRKARANKLASA
>A0A1Y1WL31|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Linderina pennispora|TrEMBL
MAVAGREVVGWVLRIGGISALVAATTTLFLYDRQRVRQSAKRLPRHRSAGTPFFSFEYFP
PKTEQGLVNLYDRIERMSKLGPLFVAVTWGAGGGHGGSARWSCAGHAKGVFGIETVMHLT
CTNMDKAKLDSALESAKAANVQNILALRGDTPRGSEYWTACDGGFSHAADLVRYVRQKYG
DYFCIGVAGYPEGHIENPDKDRDFEFLVEKVQAGADFIVSQLVYDPETFIKWEQKCRSAG
IAVPILPGSFRRLLHLTKVSVPEPLGTSLEEVRANDQAVKELGVEHAASTIRALQKAGVW
GVHVTTLNLESSVQRPRLWDDFPNGRWGDARSPAFGNLSTYGEMLKFDPRGAAHIWGRPQ
SLDEISQLFERYVTGQITSLPWNDEPLRAESDRIRDELARINRLGYWTLASQPALDGVSS
ADELHGWGPRGGYVYQKAFIECFVPGDRFPGRTPRVTYYASNMRGDFLTNAYGEAATALT
WGVFPGRAVVQPTLIEKISFLAWRAEAFQTWREWMQGCEFLEKVAHECWLVNVVDNEYKS
PDAIWDLFI
>A0A4Y9EUJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus tengchongensis|TrEMBL
MKIRDLLKARKGPLFSFEFFPPKTPEGEEALFRTMEELKAFRPAFVSITYGAMGSTRERS
VLWAKRILGLKLNALAHLTVAGQSQKEVAEVLDRFVEAGVENILALRGDPPQGERAFRPH
PEGFRYASELVAHIRARYGEGLSVGGAAYPEGHPESTSLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIEIPILPGIMPITSYTQLRRFTEVCGASIPGPLLSRLEKYQ
EDPKAILEIGVEHATRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGFRPWARTSEGV
>A0A1I1PB56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiohalospira halophila DSM 15071|TrEMBL
MESQKKFEKSFSIEFFPPKSEEARDRLHRVRDKLMTLNPHYVSVTFGAGGSTQQGTVETV
QDMLNAGLDAAPHLSCITSSKDEIRELVNNYRDMGVKRIVSLRGDVPSGMRGPSGEFRYA
NELVEFLRSEYGDTFHLEVGAYPEFHPQAPSASADIDNFARKVKAGADVAITQYFFNADA
YYRFIDQLEKRGVDIPVIPGIMPIINWEQLKRFSGMCGAELPRWMSWRAEELADKDDKEG
LQAFGHEVVGTMAEELLAQGAPGIHFYSMNQAKPTMKLWQDLGIRT
>A0A1U7MIJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa sphaeroides DSM 2875|TrEMBL
MTTKPSLREALADSAQLSVTWELVPGRGAREKAQEHLVKMAELAAKDARINAVTITDNPG
GKSAIAAYAMAVEAKRLGIEPIVHYTTKDKNRNALESELYALDRADIENLLVMTGDYPIQ
GYAGNAKPVFDFDAVHALRMITKMNAGAYTKLPPTHFFAGAVVSPFKSTEAETMAQYYKL
HKKIANGAKFIITQLGYDARKFDELKKYVDMHNLAVPLIGNIFVLSLPVAKMMNKNLIPG
CVVTDSLVARLEEEATQSNKKELQLLRAAKQYAVLKGLQYDGVNIGGHGMGYADIQYIME
KGEELSADWQDIARTEFNHPQDGGFYFFEQDESTQLNTCQPVDRTRTGSSNSSLRLKLMD
MVHETAFDHKAPLYPMNKAIAKYIDKSWVKQPFTIAEYTTKTMTNQCRFCGDCAMHELGF
ICPMSQCPKQQRNGACGGSRDGWCEVYPGKQKCIYVTMYEGFKGHGKEERMKDKYMPPCN
WDLHRTSSWLNYFNDRDYNTNKE
>A0A3R7IWN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haloarcula sp. Atlit-47R|TrEMBL
MALGTHAVSNSQGVQTLLTSARFELMPFESFDEEITHLPDDATIAITTSPQLGIEKTVEK
TEQAAAMGYDVVPHVAARYVEDRAQLEAIAERLDQAGITDIFVPGGDREEPAGEFESALD
LLEALADTEYDFEEVGITGYPEGHDFIDDETLAESMARKAPYATYIVTQLCYDPDAVLEW
VEEIRARGIELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGILGFVKQLVGSRG
TYEPDELIDGLAPYVGDNDYNIRGIHIYTFNQTPDTEKWRHKRLDS
>A0A2N2P121|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-10|TrEMBL
MSSSSHFLNLIEKGRPLVSDGAMGTVLHQRGTRFDDCFDGLNLQNPDVVGEVHKAYIEAG
TDIIQTNTFGANRYKLARYGLEDQVAAINVAGVNLARSIITASKKPILLAGDVGPLGVRL
APFGRVQLDEAREAFREQISALLSAGIDLLIIETFTDIYEINEAILAAKELAPELAVIAS
MTFTRDDRTLLGDTPEKVAQKISSAGADLIGINCSGGPLQLLRILKQMKKAVPHGWFSVM
PNAGWPEQQDGRIMYPAGPEYFGDYAQAFWQFGAKVVGGCCGTTPQHIEAMARVVQNMDP
QELIMSFETPEAIRVQVDEDGAQCSELAQKMEAGKFVIAVEMDPPRGLSTKKLLAGASLL
ADSGADVINVADSPMARMRMSPWAVCSLIQQHIGVETVLHFPTRGRNLLRVQGDLLAAHA
LGIHNVFVVMGDPTSIGEYPDAMDNYDLVPSGLIKLIKQSFNAGLDHAGSEIGQPTCFYA
GGALNLGSPNMDTELKNLHRKLKSGADFFLTQPVYDAEAAIRTISWLQEQCSGYQLNILV
GILPLASDRHAAFLHNEVPGIVIPEDIMLRMQSAGKAGAKEGIKIAVELINALKNSAQGI
YLMPAFNRFDYAAEIIDAVKTEN
>A0A0B6X0F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrinomonas methylaliphatogenes|TrEMBL
MEAIRELIESDRVTIFDGAMGTMLYSKGIYINRCYDELNLSHPDLVREIHAEYVRAGAEI
LETNTFGANPYKLQQFGLEGSLRLINIAAVRLAREAAGDRCYVAGAIGPLGLRIEPYGPT
SFDEAKEMFKEQASALLEGGVDLFVLETFSDISELRQAIRAVRELCDLPIVAQMTILPDG
NTSFGTTPEIFAARLDEWGADVIGLNCGVGPAIVLAAIEKMRGVTNKPLSAQPNAGLPRD
VQGRQFYMCSPEYMAKYAKRLIQAGARFIGGCCGTTPAHIKQIADAVRAISPRRQYVVVQ
DKPKRIEELTPADIRVVPPEERSRWSRKITRGEFVTTVEVLPPKGCDASQTLEQIRLLKA
AGVDAVNIPDGPRAQTRMSAMATALLVEREIGLETVLHYCCRDRNLLGMMSDLLGAAALG
LRNLLLITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGQPTAFCIGVG
VNPGALNLEHEIRRFEWKVEAGAQFAITQPVFDVDQLYEFLRRIEHVRIPIIAGIWPLVS
YRNAEFLHNEVPGVRVTPEIMERMRKASEKGKEAAREEGLKIAQESLREIRDIVQGVQVS
APFGNVRYALEVFSVLPEFARATERIALGERA
>A0A367L3G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps polyrhachis-furcata BCC 54312|TrEMBL
MPLPATDEIMSLRQLTLQPTVAMDKITNKIAALPDGAEYISLEFFPPKTAMGFANLRHRL
QRMEQALRPLFVNVTWGAGGATAIKSLELAELCQRELGLTTCLHLTCTNMSRRMIDRTLE
DAKVLGIRNILALRGDPPRKEEYREAIGNDDDDDNNPVEFTWAIDLVRYIRRKYGDYFCI
GVAAYPEGHADGSHPQEQSLEHDLPYLVDKVRAGADFIMTQLFFDMEAYEKFERTLRDHA
SGLFSTMPIIPGLMPIQSYQMIKRTTKLSHAKMPDAILARLDAVKGDDERVKKIGVDIVS
ELIEQMRAIRRGSSSRRGFHFYTLNLEKSVSLIVEQTGLIQEDSSDDAVLDGLLSPPPTM
HSNGNRQTSHSRSSRRQSSVGSDPHNRVIVGDRPLTNPEWEATGQEAGVPASSVNSRANT
LAICEGEGVLGREATWDDFPNGRFGDARSPAYGEMDGYGVSLHMSVTQAERLWGHPTTPE
DINRIFVRHVRGDLAAIPWSEEGLMAESATIRDQLVELNNKGWWTVASQPAANGAPSNDA
TLGWGPPNGFVFQKAFVEMFLPAEDWRRLLERLRSDSICFYAANAAGDFVSSDESGGVND
ARVASSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIWGEWARVYGRGTASEKLLS
GIREDYWLVNIIHHEFLEPEALWDLLR
>A0A3S3LF73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrococcus lahaulensis|TrEMBL
MSALPYSFELFPPRNDAAAARMLEAVDAFAAVEPAFVSVTFGAGGTTSRHSLGVLQRLLD
AGVSPMAHLTCTGLGVSDTARLVRQFLDAGITRFLALRGDPPADGVPEPATSLRSAAELV
QLIDRVDSERVPYAEVPLPGLRASALAERRCGVEIAVAAFPNGHPGAGVHRGDVDALLAK
QEVGATLAITQLFHDPYDYARYVELARARGVTIPIVPGVVIPTSHRRLVRSAQLAGEGLP
RVLAERLERATPEEAVAIGVDAAVALIDSLAEHDPPGVHLYTFNDHRPAIDVLHGIGALA
PTRTITTGAP
>G2WQ21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)|TrEMBL
MHIKEMLADAERDGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIA
ELTCEMVTQAQSVYGLETCMHLTCTDMGLDKVNDALRKAYKAGCTNILALRGDPPREKEK
WVAADGGFEYARDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEESLLDHLKEKVDMGATF
IVTQMFYDADNFVRWVGKVRERGITIPIVPGIMPIATYASFMRRAKHMNCSVPQEFMDAL
EPVKNDDNAVREVGKVLVAGMCRKILAAGIHHLHFYTMNLAQATRMVLEELNWMPTSERP
LKQALPWKQSLGLGRREEDVRPIFWKGRNKSYILRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNIKKWGEPQTVQDIATLFVRYLRNEIDCLPWSESPLTNEADPIREDLIA
LNKRGIITINSQPAVNGVKSSHAVHGWGPKNGYVYQKSYLEMLVHPDLYPEIISRIEKHP
DMTYYAVTKSGNLKYNAPSDGPNAVTWGVFPGKEIVQPTIVEGISFVAWKDEAFRLGLDW
AHCFEQSSPSRVLVELNNDFHQQREIFDLFEGLSVKEYDDIKPVAKDVAPDAVSAPTNGT
TNGIAVPAA
>A2QUJ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus niger (strain CBS 513.88 / FGSC A1513)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDGQDPARDLPFL
IEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTK
LSHVKIPPHVLSKLEEVKHDDDAVKRIGVDIISDLVHGIRDLVSPGLRGFHFYTLNLEKT
VSFILERCELIPPYTEIDDSDALADGGNLSALDSSSYIAPNGAPIRTLASRRSSVSSIPH
NRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFP
NGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWS
EGGAEEDSNGLNAETAIIQPELLTLIDKKGWWTLASQPAINGVRSDDPVFGWGPPGEGFV
FQKPFVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNTDDPDPIDIN
PANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDDTK
NDVWLVCVVGQEFGAGTEPGSEEEEDEKKWMWRELANSQ
>A0A2N6PYD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. UMB0228|TrEMBL
MSSTFDASHASRVPFSFELYPPRSESSQEALHETVRRLAAAGPEFLSVTYGAGGSTGGRS
LDVLRFIREHTDVEPLAHLTCVGNTYAGATALIREFLDAGILRFLALRGDPPAGQSEPFL
GDLESAAQLVQLIDRVQAERAPYQESPVPGLPGAALVAPRQKVDIAVAAFPKGHPRATHR
TQDVEALLAKQAAGATFAITQLFFHPDDYLAFVERARAGGVTIPILPGIMPITSPARLAR
VLELTGEDLPSELAIALDVEPTAEGRREIGISWAARLAADVVAGGAPGVHLYAFNQHETV
LTVLAEAGIVPALRH
>A0A2N2BNK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-4|TrEMBL
MRITELFQRGEFVLTAEVGPPKGVELDHLIKDAHEYLKTRVHALNVTDNQSSVMRTGSLA
TCKVLKDEGLLPIFQITCRDRNRIALQSDVLSAALLGIENLLLLTGDYTTLGDHPQAKPV
FDLDSVSLIHAVKRLEEGFDIAGNAVDGAPPKFAKGAVVSPCSDSVDVQLAKMEAKVKAG
CEYFQTQGVYEPEKFIKFMEQAKQFGVPVQLGLIIPKNVGMCRYMNANVAGVHVPDEMIK
ELQADKEKTKAGDTGVEICARLIKECKDYAQGVHIMSLGWENRIPEILDMAGIAPITPVV
>A0A4R8TUT4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum sidae|TrEMBL
MHIKSMLDETRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREHEK
WEATDDGFQYARDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGASF
IVTQMFYDGDNFVRWVGKVRERGITVPIIPGIMPIATYASFLRRAKHMNCKVPDEWMAAL
EPVKNDDVAVREIGKGLVADMCRKILAAGIHHLHFYTMNLAQATRMVLEELNWMPSNERP
LKHALPWKQSLGLGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPRSIKDIANIFVRYLETEIDTLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSSHPVHGWGPPNGYVYQKAYLELLVHPDMYPEIISRIEKNP
DMTYYATTKNGPLKYNAAHDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGTDW
AHCFEAGTPSRVLLDRIMNEWYLVNIVNNDFHQKTALFDLLDGLSIKEYNDIPSEPQVQT
NGQANGVSKEQASELSNGNVAAIPA
>A0A259IR14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azorhizobium sp. 39-67-5|TrEMBL
MTSPIRASRETSRPPVRVSFEFFPPKTEEMERTLWASIDRLAPLGPSFVSVTYGAGGSTR
ERTHATVERIARETGLAPAAHLTCVAASRAEIDEVVRDYAQAGIRHIVALRGDPVTGVGT
AYEPHPQGYAHACDLVAGIRRLGDFEVSVSAYPEKHPESPSLDADIDYLKRKVDAGATRA
ITQFFFENDVYFRYLDKVRAAGIDIPILPGILPVTNFKQAANFAGRTGASVPAWLLKRFE
GLENDPETRKLIAAAVAAEQVTDL
>A0A356L1W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oribacterium sp|TrEMBL
MKIIDILKQDQITLSFEVFPPKKIETYDSVQAATEGVAALHPSFMSVTYGAGGGTSEFTL
NIAKNIRDKYGVEVLPHLTCVSSTKAHVHAMIQKFKEYGFENVMALRGDIPEGGAPYDDY
HYASELVADIKAQGDFCIGGACYPDGHVECAHKDDDIKNLKRKVEAGVDFLTTQMFFDNA
EFFNFLYRLREQDIRVPVLAGIMPITNQKQLGRSVALSGTTVPTRFKEIVDKFGDHPEAM
KQAGIIYATEQIVDLIANDVKHIHVYSMNKPDVAEAIQRNLCEILKV
>A0A367L1T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps polyrhachis-furcata BCC 54312|TrEMBL
MHIKQMLLQAENGHQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQSVCGLETCMHLTCTDMGLDKVNQALSKAYKAGCTNILALRGDPPRDQKQ
WTATDGRFQYARDLVKHIRHTYGNHFDIGVAGYPEGCDDNKDQDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVGRVRDRGITVPIIPGIMPIATYASFIRRANHMQCTVPSQWMDAL
EPYKNDDVAVREIGKTLVADMCRKLLASGIVHLHFYTMNLAQATRMVLEELEWAPCPERP
LHHDLPWKQSKALGRRHEDVRPIFWSNRISSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRNKWGAPTTVRDIADTFVRYLDQEIDSLPWSESPLTGEADVIRPNLKA
LNKCGLLTINSQPAVDGAKSSHPVHGWGPSNGYVYQKAYLELLVPPDIVGEMIRRVEARP
SLSYYATTKDGDLMTNVCSEGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
GHCFDEESPSRGLIDKIMNEWYLVNLVDNDFRNNSAIFDVLNNLQVKDLDVPYAA
>A0A2I7SIK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tamlana carrageenivorans|TrEMBL
MKVTDHIKKANGKTLFSFEVIPPQKGKNIQDLYNNIDPLMEFNPPFIDVTTSREEYVYVD
RGNGLLDKRITRMRPGTVGICASIMHKYKVDAIPHLLCGGFTKEETEYVLVDCHYLGIDN
VVALRGDARKDESYFVPTEGGNAYASELVQQISNLNKGQYLHDDIKVEHNYDFCVGVAGY
PEKHMESPSLNTDLKRLKAKVDAGADYVVTQMFFDNKKYFEFLDKARTIGITVPIIPGIK
PIAVKRHLQILPQVFKIDLPEELIEAVEGCKDNKAVREVGIEFAIQQSKELRDAGVPFLH
YYSMGKSDNIKAIASALF
>A0A1C1YYR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea olei|TrEMBL
MNSSSRANAAGSAQRIKVSFEFFPPKNGDMESQLWDSITRLAPFQPDFVSVTYGAGGSTK
KPTLNTVARISRETALAPAAHLTCVGSDKTDVDAVAREFQAVGVNHFVALRGDPPEGVGA
AYRPHPGGYANAAELVAGLRAISDFEISVSAYPERHPESPDFATDIDMLKRKVDAGATRA
ITQFFFDNDVYERYVERVRRAGIYVPIVPGILPVHNFAQVARFSKLCGASVPERFARRFD
GLEKDPETRALVAAAVAAEQVNDLVERGIDDFHFYTMNRAQLVYAICHILGLRGQERTAV
GAAA
>A0A523WGW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aminicenantes bacterium|TrEMBL
VRMNPVAFSHLVKERGLEPIPHFALRDRSLTRIQSDLIAASALGLNNIFAISGDPPSLGD
YPQSTAVYDITSPGLIKLIKLLNTGKDFAGNVYTNPTYFYVGAAINPSPPDLKREIAKIE
EKIDVGTDYFVTQPLFDSKTLIGFIEKVDLKNTPVVLNLFIPKSKKQFAYIANEVPGIRV
PQNLMKIVEEKDVWLPFLQDELIKVLQELKPAISGLYIAVPRGGTAYLRPFMEEIKGKKW
GL
>A0A4U6BG04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobiaceae bacterium LC148|TrEMBL
MKSTGAREAFGVSFEFFPPKSDEMEAQLWDTVEKLVSWNPDFVSVTYGAGGSTKAPTIEA
VRRLIHETPLATAAHLTCVDASREEVRAVVDEYRATGVRRIVALRGDPTGGIGTAYAPHP
EGYSDTADLVRALVEFGDFDISVSAYPEKHPESPDLSADIETLRRKADAGADRALTQFFF
DNDIFERYLEKVAAAGITIPVVPGIMPIQNLTQLKRFARRCGSSVPSFLDDRFEGYDDKP
EERAEIAADIAAEQIEDLMGRGIRDFHIYTMNRAPLVSAVLERLGRRRMEEKAGAAA
>A0A1U7MFH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa sphaeroides DSM 2875|TrEMBL
MTLIDKLGKSFVFTTELGGINGTDIEGSIAKLKEYDGVDAINIHDCPNGRLRMNSVMAAA
IIKQVAGVETIPHFTCRDRSLLGTQADLLGAHALGIRYMLPTTGDGPQHGPYQSAAVYDY
NTAKLIELIKNFNQGKDANGEAFTGQTQFAVAATATPGAANLAAETANMQRKISAGADFF
QTQPVYDPEQAGRFIDKAKSLGKPVLLGLMPLKSLKMAEFVNKNVAGVTVPAHILTEMEQ
GKTGFEIACEFICQIYRQVDGIHIFGMGDVAVTNKVVAFARELLNRR
>J3C832|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. (strain CF136)|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKVGGNNFAIDLVKQINQLNCGKYLHEVMDVDNKADFCIGVAGY
PEKHLESPSLQSDLRRLKEKVDAGADYVVTQMFFDNTKYFEFVAKAREMGITVPIIPGIK
PIAVQKHMQILPQIFRIDLPEDLIHAVDKCKNNAEIRQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQIF
>A0A853IYK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ottowia beijingensis|TrEMBL
MSFPISLEFFPPKTPEGAEKLRVVRSKLYALAPDFCSVTFGAGGSTQEGTLDTVREIVGE
GQHGVPHLSCIGQTQASIRQRLATYQAAGVKRIVALRGDLPSGYGSGGEFRYASDLVAFI
RAETGEHFKLAVAAYPEYHPQARSPEADIDAFAAKVRAGADVGITQYFFNADAYFRYVDE
LRRRGVDTPIVPGIMPITNSTQLLRFSDACGAEVPRWIRLRLQAFGDDAAAIKDFGADVV
AALCERLRAGGAPSLHFYTLNQSVATLEVCRRLGRCD
>A0A3M1NS00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MKRKEFLKELEKRVILFDGAMGTMLYNRGVFINQCFDNVNLSNPRLVKEIHTGYANAGAD
VLQTNTFGANRFKLSKHGLSDSLEAINYQGAKLAREVAGEQLYVAGSIGPLGVKIEPWGK
LSREEAREAFREQAEALLNGGVDLFVLETFSDLGEIEQAIRAVRELCDLPIVAEMTIDES
GNSLYGTSTEVYTYQLDKWGADVVGLNCSVGPPPMMDALEKMVHVTRKPIVIQPNAGNPR
VVEERNMYLASPEFMGEYAMRFIKAGARLVGGCCGTTPEYIKAMEKSVRMLSPRQHNFTI
SIPKELEQEVPSVPVAEKSGFGAKLANGELVTSVEIVPPRGSDPSGVVEACQKLKAFGVD
AINVPDGPRAMCRMGAQHLSVIIEQNVGMETILHYCCRDRNLLGMQSDILGLAAIGLRNI
LIITGDPPKMGDYPDATAVFDVDSIGLTNMVNRMNHGVDLGGSKLDAPTRFLIGVGVNPG
AIDLEQEIRRFEWKVDAGAEFAITQPVFDPQILLDFLPKIEHVKIPIIA
>A0A847N8D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gracilibacteraceae bacterium|TrEMBL
MKIKEFFKNKPVISLEIFPPKPEAPIDTILSTIDQLSDLKPAFISVTYGAGGGTKSHTVK
IADIIKNKYNIEALAHLTCVGATRADIDSILEQLRKSNIENIMALRGDFPAGFDPTSGTH
GQYKYAGNLIEHIKKAGGFCIGAACYPEGHIECPDKVQDLKHLKLKVEKGADFLITQLFF
DNEMFYSFKEKLEILGVNLPVSVGIMPVINKKQIERITGLCGATIPVKFRRILDKYGYNP
AALKEAGIAYAAEQIIDLLSFGVDGIHLYTMNRPEVAIGIISQISEIRSFYDSSNIPV
>A0A381ERN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium violaceum|TrEMBL
MTQTPRTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGQAAAPHLSCIGSTRENIAAILNEYRGNGIRHLVALRGDIPSGMVAAGEFPYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLANFVRKVRAGADSAMTQYFFNADSYFRF
VDEVRARGVDIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRLRMQSYYDDTASIRALGL
DVVTELCDRLLQGGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A2I9DIJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenibacter sp. NBRC 103722|TrEMBL
MKVTEHIKKAEGKTLFSFEIIPPVKGRSIQELYDNIDPLMEFKPPFIDVTTSREEYVYID
RDGLLDKRLTRMRPGTVGICASIQHKYGVDTVPHVLCGGFTKEETEYVLVDCQYLGIQNV
MALRGDARKEEQYFNPTKGGHAYASELVKQIHALNHGNYLHDKVETIHSADFCIGVAGYP
EKHLEAPSLITDLKRLQEKVEAGADYVVTQMFFDNQKFFEFVEAAKKMGINVPIIPGIKP
IAVKRHLQLLPQVFKIDLPQDLIDAVDDCSTNADVRQVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIEAIAKELF
>R6AZE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia intestinalis CAG:13|TrEMBL
MKFFRFVDDCRIAEINVPVIPGIMPVINAAQIRRMVTMCGASFPVRFQKIIHKYEDNKEA
LFDAGMSYALSQIIDLLESDIDGIHLYSMNNPLVARKICEGIRHII
>A0A1M6G6L1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerovibrio lipolyticus DSM 3074|TrEMBL
MGRISVELIPRSEDGLREDLQIVKKNAPGVELINIPDLLRFDMRSWQGAAIAQEYFPAVM
PHIRAIDVDLSQPLSMRPELRQSGITEVLVIEGDPPQDMSHKFYPTVTTDVISKFHQEMP
EVKVYAGIDQYRGSMRQELYRIQRKLQAGAVGFFTQPFFDIRFMEMYADMLDGQNVYWGV
SPVMSERSQSYWELKNNVIFPKGFQPTLEWSIEFSKKALKFAEERDANLYLMPIKSNLEA
YLQGVLG
>A0A3M2INI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MHVIDAIKNAKKPLISLELTPPNKGQSIEELYRTMDVLMPFKPSFINVTYHQAHVVYEEI
NGVIYRIPKRKKPGTVGICASIANRYNIETVPHFICAGFSKYETEDALIDLHYLGIENIL
ALRGDPAVGERHFIPHKDGHRYASELVKQISNMNKGIYLEDLEDAHPTNFCIGVAGYPEK
HFEAPNFEKDLQNLKHKVDQGAHYIITQMFFDFQVYKNFVERAREIGI
>A0A165YCH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peniophora sp. CONT|TrEMBL
MKLADKFASADKPFYTFEFFPPRTDQGFENLLPRIGRLAQLKPQAVAITWGAGGSTKDRS
LDLASLTQKEYGIDTVLHLTCTNMQQGIVDDVLRAAKALGVQNIMALRGDPPRGEEYWIP
ADPRFKRARDLVSYIRNTPEFADHFSIGVAGYPDGHTDAVVNTASEDEEIEYLKEKVDAG
ADYIVTQLFYDVDNFLRWLKRIRDAGITVPVIPGIMPLQTYASFQRLTKLTGAHIPAELD
AQLEPIKTDDQKVKDFGISLAISMIKRLSESSDVRGFHFCTLNLEKSVQRILDALGWSSG
ASRAQNKLITENDGAHGDPQKPGLLVTPAEAATSLQDSKAPKGELGKGEVNNASAWDEFP
NGRFGDVASPAFGNSNQWGGYSFSNHNRNVWGAPRTLEDISNIFLAFLKGDISAFAFSPM
PLSAETALILPHLTKLAERGMWPVGSQPAIDGARSDDETVGWGPSGGYVYQKAFVEFFCT
DEMADALEKKVREHGHGVVDLLMAQADGGEEEGHGFIERTQGDRNAVTWGVFPAQEIVQT
TLIEAESFLSWKDEAFATWSAWAALFPPDAAERALLERVRKKRWLVNVTHHDYKDADALW
RFLLED
>A0A0C3S5A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phlebiopsis gigantea 11061_1 CR5-6|TrEMBL
MKISQKIQQAEKEGRIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRSS
DLTSELVKTCQGMIGLETCMHLTCTNMPKEKVDVALREAKASGCRNILALRGDPPMGQDE
WEAVEGGFVHGVDLVRHIRKEYGDYFDIAVAGFPQHQELPTAERDLEIQWLKEKIDAGAN
FIFTQMFYDVEIFISWVKTVRAAGITVPIVPGIAPIQTWNGFIKSTTLSRTSIPQAILDQ
LEPYKNNDEKVREIGIKLVGDMCRRILAENIGIRGLHFYTMNLEKGTRMLLEELKLVPHV
EVVKPLPWRQSLTPSRRSETIRPIFWANRTKSYLTRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQSKEEALKLWDHPTSLADVSALFARFCLGKLSALPWSDSPPSSETSVIATQLA
RLNELGFLTINSQPAVDGVRSDDKVHGWGPSNGYVYQKAYLEFFVSPELLDALIPHIERD
PNITYYAINKRGDLRTNTQSNGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGRR
WAMYYEPDSPSRKLVSDFMDTFLLVNVVHNDYKRPEGIFEPFVKAAADFAAKQPSLLTGS
LNGHSNGHANGHANGEAH
>A0A5E8KW35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae|TrEMBL
MISIDMPSHTRAITDAYSLEVSVKDIGALTKAAPRLLPGSSMFIPYLPGQHDAARLAAAQ
LVRSLGFEPMPHLSARRIGAPEELQAFVARLVDEAGVTRCFVIAGDPSTPKGPFADSLSL
IETGVFERSGIRTIGVAGHPEGHPIMRTAEQWDVLERKCRSIQERGMAPLIVTQFGFDAD
MVVTWVEALRARGIPHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLASRLTDAHGDIRLHVFPFGGIAQSVAWVAQYRSRASSQDRMSSVRADQA
>A0A0N1LJ18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|alpha proteobacterium AAP81b|TrEMBL
MTLSLPQMAEAARALNGPLFADLPGDIAVSFEFFPPKSEAMETTLWESVETLAPLAPRFV
SVTYGAGGSTRERTHATVARIARETSIPAAAHLTCVDASRDAIAAIARDYWAAGVRHIVA
LRGDPPTKDRRFEARADGYADATALVAGLRAVAPFEISVSAYPECHPEASCLDDDIDNLR
RKLDAGATRAITQFFFEPETFFRFRDAAAARGVGAEIVPGILPVSNFANLLRMAGPCGTA
VPGWMATLFQGLDDKPAARQLVAATVAAEMCRRLYAGGVRHFHFYTLNRAELAYAICHLL
GVRPQVAAMEVAA
>A0A2N2PF90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division BRC1 bacterium HGW-BRC1-1|TrEMBL
MLLSEIYAATRPALSVEFFPPRTPAGEVKLAERIPIIAALRPAFVSVTCTNLRCKTVEWS
ARLRDEFHFEVMTHLTCIGYSADEIRAQLDELRTLGIRNLIALRGDPPPGETDWTPHPQG
FHQAIEMVRLAREAGDFGIAVAGFPETHPQAESPEGDIRRLKEKVDAGADVIMTQLFLDN
DSFHRFVDRCTAAGITVPIVPGILPFKTVAQLRRFTSQLAQTYHGPTRIPAALEARLAAV
ENDDDAAFELGVDWATEQCEDLLAHGVAGIHFYCLNESLAVETIMHRLGYPRT
>A0A2N3FFG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium HGW-Actinobacteria-8|TrEMBL
MTIRDLLAAQHTTLSYELFPPRTPAAEETLTATMQVLASTRPDFVSITYGASGSTRSTSR
GVVQRLAESHTIPPLAHLTCVSQSRAELIVVIEEYLGEGVSDFLALRGDPPKGQTDWTPH
PDGLMYASELVALLREVAAAHGIDISIGVTAFPAQHALEQWRQQGLDVLRAKQDAGADFA
ITQVFYEVPHYAALVRDAAAQGIGLPIVPEVMPLVSARRAYRAAELTGVPTPGELLGALE
AAENDDEALAAGVAHAARLSRDLVEAGAPGIHIITFNQHRAACALVDALGLR
>A0A838A5E3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides sp. LB1|TrEMBL
MTTNPLDRDGRVAELQDPGSIVDRLAAVQPGEVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVGELRAMVGAYVDRG
ITNILALRGDPVGDVNAEWIPHPGGLTYAEELVRLVRDLGDFHVGVASFPEAHPQAIDLE
HDTVHLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSL
RRQVELSSSTLPLALEERLLRAAGDGPDENRDEVRKVGVEVTTAMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRITPGSGRA
>A0A848GDJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga fulva|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMDFKPAYINVTYHRSEHMFKKK
ADGAFEKVEIRKRPGTVGICAAIMNHYTVDAVPHLICGGFSREETENALIDLAFLGIDNV
LVLRGDAPKNETFFEPDPHGHSYASELLDQVVHMNNGVYLEDDLQGGVKTNFCIGVAGYP
EKHFEAPNMQTDMSYLKRKVEMGADYIVTQMFFDNQKFFDFVAKCREMGITVPIIPGLKP
LTSKKQMNILPRIFHVDLPTELSSEIMRCKTDKEVEQVGTEWLIQQSKELKAFGVPVLHY
YTLGKPQVVRKAVEAIV
>A0A7J2UWZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon|TrEMBL
MSYRSNLEKILSEGRFVVTAEIGPPKGADANMIRDKVKLLRGSADAFNITDNQTAVVRLS
SLAGSVILLQMNMEPIMQITCRDRNRIGLQSDVLGAAALGIRNMLCLTGDHQSFGNHPAA
KGVFDVDSIQLLQIIKNMRDEGVFQSGDLLLSGRPPAFLGASANPYADPFEYQVDRLRKK
IDAGAEFIQTQSVYNLEKFSKWMDDVRSQGLDKRVHILAGVTPLKSVKMTERMKFHVPGT
DVPDVVYQRMKHASDPAKEGYRIAFETIRELKNLPGIHGVHITALFWEEIIPVLVKDAAL
ISRI
>A0A8E0I755|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus paracasei subsp. paracasei Lpp122|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNIALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDMEPVAHLPAAQLTREQVDAELRGFQDAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQVGDFNVVAACYPEKHPESPDVVSDIHHLKEKVDSGASQLISQLFF
DNQVFYRFRERAQLAGINVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIVDLLVHGVDGIHIYTMDNPTVVKRIAAATQTIRNA
>A0A1R1MM72|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurobacterium indicum|TrEMBL
MSFSEKINNGKFIITAEVAPPRGTYYQTIIEGIKPLKGYVDGFNVTDNQRSMVRASSIAM
SRVLLENGFEPICQFTARDRNRIALQSDLLGAYILGIKNICLMTGDFTTLGDEKGAKPVF
DVDSLLMLKIVKTLEEGHLINGKELKGKPSFNVGAVFNPFAGPEKLQIEKLRKKVELGAK
FIQTQPVYDIETAKRTHEIIKETGAIPIIGLLPIKSLKMANFIKKLNPKSVPDKFIEKLA
SAKDPHTYGWEYTLEIAHGIAEFGRGIHFMLVGKTYELAKFIDYLKNESPYNHKF
>W8KXE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodospira haloalkaliphila|TrEMBL
MKTQKQHERTFSFEFFPPKNDEGAKKLKDTWTELAKLEPRFFSVTYGAGGSTQARTLETV
LDIHKNSGVDAAPHLSCIDSTAEQMRGILQLYKDNGLRHIVALRGDLPSGMRDPGEFRYA
NELVEFIRKETGDHFTLEVAAYPEFHPQAPNALKDLQNFKRKVDAGADSAITQYFYSAEA
YFRFVEDCEKLDINIPIVPGIMPITNYKQLARFSDACGAEIPRWIRKRLEAFGEDTASIK
AFGEEVVTEMCDQLLKAGAPGLHFYTMNQAGPIKAIWKNLGLKPEPR
>A0A0A0E049|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalispirochaeta odontotermitis|TrEMBL
MKLKEALQKKKFVVTSEVQAPVDQEPEDLVRSLSQVRGRVDGVSLSEVEFEGIVGDTIKT
CELLNTNQLEPIYQTTTRDKNRLQLQKDLVEAHRAGIDNLLVFTEDYRITGDSLQEMMFF
HVDAGKLQSVLEHIRQGETVEGDSLDAKADFLVGSGVESAWGKNVPDLEMKEMEEMTKMG
AGYFLTTPIFDVDQFAKFLKKAETFDVPVIAEVMILRTAGMARFLNRHIKSGMVPDWIIQ
KLTRAPNRQKASIEIFNDIVSGLKDLCQGVHIITIGAEDNLKLYLDAAKLK
>A0A5B8YJI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Antarcticibacterium arcticum|TrEMBL
MKITEHIQAAAGKTLFSFEILPPLKGQHIQSVFDSIDPLMEFNPPFIDVTYHREEYVYIE
MENGLLEKRVVRKRPGTVGICAAIQSKYKVDAVPHILCGGFSKEDTENFLIDLDFLGINN
VMALRGDAVKSETYFKPEPKGNFFANDLVQQIAGMNQGRFQEEPLENSHSTDFCIGVAGY
PEKHMEAPSLEQDIKRLKDKVAAGAEYVVTQMFFDNSKYFEFVQKCKYNGINVPIIPGLK
PIATKNQLNLIPHRFKVDLPEDLIQEIAKCKDNTEVRQVGIEWCISQSRELIAAGVPVLH
YYSMGKSSNIRAIASAVF
>A0A1D9GGG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter salinus|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTRQEIGELLDVYKENGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLQNFARKVKAGANSAITQYFFNADSY
FYFIDRLEKMNVTIPVVPGIMPIINFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCEKLLKAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A8E2BV49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium meliloti|TrEMBL
MNGRTPYPVDCDGLRFSFEYFPPKNDEMETQLFQTVTALSVFAPAFVTVTCGAGGSTKAR
SLTTVKRMIGEMEIANTAAHLTCVGAPKAEVDAVIDEFLACGVRHFVALRGDPQGGIGSV
YEPFPGGYENAAALVKALRARGDFEISVSAYPEKHPESPDVAADIDMLKRKVDNGATRAL
TQFFFDNDDFERYLERVRRAGIAIPIVPGILPINNLTQVQKFAGLCGARVPESIVSRLGP
IDDQPEERFREAAHIAAEQVADLVRRGVSDFHLYTMNRPQLITAVCELMGYDPEIAPAQP
ADTERSVRAVARA
>A0A6L6PMQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella radicis|TrEMBL
MDNPNFSIEFFPPKTAEGAEKLRVTRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILA
AGEDAAPHLSCVGGTRESIRDILAEFKSHNIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGDWFHIEVAAYPEVHPQARSPQDDLLAFERKVKAGANAAITQYFYNADAYFNFVE
QTHKLGINVPIVPGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDTASIKAFGLDV
VAALGERLLKGGAPGLHFYSMNQAAATTALWQRLV
>A0A8D9VRM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae 1291|TrEMBL
MQNYAKEINALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYG
ANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGDE
PAGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVI
TQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEG
LDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>A0A8H5K930|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium phyllophilum|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDAENFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVDGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVETGPIANGTAATAVAN
>A0A329BT96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia bryophila|TrEMBL
MKPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVVDIAR
EGIEAAPHVSCIGSSKDSLRAILNEYRAHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPRHDMDNFVRKVKAGANSVITQYFFNADAYFRFVD
DAQKLGVDVPVVPGIMPITNYSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTDLCERLLDANVPGLHFYTLNGAAATKAICERLHA
>A0A6I6E7U7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium oryzae|TrEMBL
MESSATPFSFELYPPRTRSRTAALEETIRRLAAAGPEFLSVTYGAGGATGGESLRVLRWI
RENTDVEPLAHLTCVGNDYATASALIREFLVAGVLRFLALRGDPPLGKAEGDVFLGDLTT
SAELVQLIHRVQAERAPYSETTIPGHPEAARVDPRPRARTTVAAFPNGHPRSRHPREHID
ALLAKQAAGADAAITQLFFHAEDYLRFVDRARAAGVVIPILPGIMPVTSPGKLARMLELT
GEPLPADLSIDLEVEPTAEGRREVGIAYAARLAREVLAGGAPGIHLYAFNEHETVLAVLR
EAGIPLRETAAS
>I0I8I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1)|TrEMBL
MRDHPFLQRLAERPLLIDGAMGTMLYARGASSEQCLEHLVVSKPAWVSEIHQAYANAGAD
ILKTHTFGANRIRLADYGLAERVRDLNFRAVRLVRDVREVSGRAIFIAGDVGPLGKRLQP
EGPLSATEAEEAFREQISVLWEAGADLLLFETFIDLEELELAVRTARKVCDLPIVASMTF
AEDGLTLVGHTPEEAVRRLHAAGADVVGVNCSVGPAAMAQTLEQMHAAAPDVRLIIMPNA
GFPERVEGRFYYPASPEYFARQTALFLTQGARIVGGCCGTTPMHIRAMRAALDEHLTVQV
GIARPTLVVQEEPPPAVKADYGVTDEVEPTELLRKLRAGKFVISVEVDPPRSFSAEKQIE
GARHAMKMGADAVNVADSPMARVRMSALALCVQIQQQVGIETIVHFTTRDRSLMGLQADL
IGARALGVRNILALTGDPPTLGDNKQSTAVYDVDSIGLVRIISRFNEGVDVAGQDMGQKG
GFTIAVACDPTRADLVQEVDRFHQKVIGGAHFTMTQPIFDPQLWLNFVRLYEERHGKFPV
PVLIGVLPLQGHKHATFLHNEVPGITLSEEALERMRKAGPNGRQEGVKMAQELLLELKEL
PYVQGVYLMPSFGRYETACQVLEVL
>A0A1X7G2P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Allosphingosinicella indica|TrEMBL
MTLAPSIERLAEPLFADVAGDIAVSFEFFPPRTEKMEETLWQSIATLAPLGPRFVSVTYG
AGGSTRERTHSTVARIQRETGLEAAAHLTCVEASRDEIDAVARDYWAAGIRHIVALRGDP
PEQGKAFASHPQGYANAVELVRGLKAVAPFEISVAAYPECHPESRNRAADLDNLWRKIDA
GADRAITQFFFTPDCFFRFRDQAAVMGIDAEIVPGILPVSNVAQTRKFAGQCGADIPDWM
DRLFEGLDNLPAARQLVAATVAAELCGRLYAGGVRHFHFYTLNRAELAYAICHLLGLRPA
PQAAEKAA
>A0A3D1NB96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTDHIAAAKGETLFSFEIVPPTKGTSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVN
KGNGLLEKKLTRMRPGTLGICASIKHKYHVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFIPKEGGNHYAADLVSQIHQLNQGNYLHGLKDIEHKSDFCIGVAGY
PEKHLESPSLTSDLKRLKEKVDAGADYVVTQMFFDNAKFFEFVAKAREIGINVPIIPGIK
PIAVHRHLQILPQIFRIDLPEDLINAVEKCKTPADIRQVGVEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASKVF
>A0A1M7S0Y0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium gondwanense DSM 13020|TrEMBL
MKNFLDRHFILETLPPRSSNAEKYIEFCREAVESGVEIIAVTDLPMGSARVSPVAPAHML
VENSIEVLMHFSRTTRNAIRIEGDLIATHMLGIKNLLILSGDDPRVGTYPFSSSIEDFSI
YDVFKLVNLLNEKGEDIAGVKIYGKFSFNPGGVFSPFEKDVSQTLERMVKKIENGCRFFV
SQPVFSQETMVNFLQETEIHKRTKIYVALMVFESVQQLQYFSKVPGVFVPKEYFHQRDDE
HLKWYSVKRTISIVESLSKYVTGFYLTSTTKDLDVIKQIAEAVSAQCE
>A0A4R0H6T5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella soli|TrEMBL
MANGLPSTLPGGAPTIRELLASGDRSFSFEFFPPKTPEAEEVLWRSIREIEQLRPTFVSI
TYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSVIGAYAGSGVRNMLALR
GDPPGGPNQPWVAHPEGLNHAIELVELIRSLGDFCVGVAAFPDKHPEAASLEADAQVLAA
KAQAGADYAITQMFFGADDYFRLVDRAAELGCDIPVLPGIMPVTNIKQIQRMADLTGMAL
PAAVTDRLLAVEDDPAAVRETGVEIATELCERLLAGGAPGIHFITLNRSTATRQVFRNLK
APVVS
>A0A653A8X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfatiglans sp|TrEMBL
MSMKLEAKIKAGEFIVLGELEPPKGSDFSMLLKNAGLVKGRVDALVVPEMANAVMKASSL
AGCAFLQGHGFDTVLQACCRDRNRLALQADMLGAGALGIQSVMAVQGEDITFGDHHQARA
VNDLDLLELLGMLQTLGGGKDMAGIELQGPPPAFIVGTTFNAGAAGGALEVELAELQKKI
DLGVRYIVTTPIFEPDRLKAVLKRIDTSRVAVIPTVLLLKSAGMARYIDRNIRHISIPPD
TIQSIQKAGDKAYQCTKIAGELVAAFREMGLAGTLISTIGWEDKLPQVLDIARL
>A0A653ABS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Desulfatiglans sp|TrEMBL
MSRLKHILESGAFAVTAECGPPKGADPGVVLKKAEILRGRVDAVNVTDNQTAIVRMSSLA
ACSLLKGAGLDPVLQTVVRDRNRIALQSDILGASALGIRNVLCLSGDHPCFGNQPQALGV
FDLDSIQFLQAVKAMRDEARILGGDPLSSPPDLFIGAAANPFADPLPFRVVRLAKKIAAG
AQFIQTQCIYHLERFVDWLDRARDRGLTEKAFILGGVTPLKSAAMARYMKNKVSGMDVPD
DIIRRMEGVPKENQREEGIRICVETIEALKAMPGVSGVHIMAIEWEEAVGEIVERALLLP
RPDVPA
>A0A316TQV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodohalobacter mucosus|TrEMBL
MKVIEHYENSTEPLISFEIIPPKRGGAVQDVFKSLDRVVEEVKPPFIDVTYHAAEAYVEE
LPDGTLKRRVRRKRPGTIGLCAAILHRYGIDPVPHLICEGFTKEESEDALIELNYLGIHN
VLAIRGDNTGSQVSLNLNGTVNKYAVDLVKQIRNMNHGDYLEDIVNAEPTNFCVGVAGYP
EKHFEAPNLDWDVKKLKDKVDAGADYVVTQMFFDNAAYFQFVEKCRENGIDVPIIPGLKI
LSTENHLKSLPKYFYLNIPDELTAEVDANPASVKDIGTEWSLNQCQELLDNGVPGIHFYI
MGDPQPALNVISGLRGR
>A0A359CAP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MPDEHAVEVEEAFAEQIGTLVAEGIDLIVLETFTHLKEIRLAARTARNLGAPVLASFALN
DRGETAVGMKAGAIAQALDADDNVDAVGINCGTGPAGVFDALQSVLPLVTKPVVVMPNAG
FPRDVGGRLLYLTSPEYFTEYAKKYIELGVRGVGGCCGTTPAHIRVAGRAVKSLSGVKKH
VEVRPLTQQGVLVQVIPPARKSRFARKMLGGEKVTSVEIVPPRSSDLSGMLAKVRKCAEA
GVDAINIPDGPRASARISPMIAAITILKEVGIEPILHYCCRDRNLIGMQSDLLGGYAAGL
ANFLIITGDPPKVGDYPQATGVFDVDAIGLTQVTANLNRGFDIGGNPIDPPTGIFIGVGA
NPCAVDMEREIERYFRKIDAGAEYAITQPVFDVEALFRFLDRVEGAERRIPVIAGVWPLV
SYKNAEFMNNEVPGVVVPRKILDRMARCRTKEEGRRAGVDIARRTIERISPRVCGFQVSA
PLGSVETALAVLGRGRLEKSP
>A0A7V7DY73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSNLEKILKAGHFAFTGELGPPRGTDAAVIREKAAFLKGNVDAVNITDNQTAMVRMS
SWAACLLLLQEGLEPNYQMVCRDRNRLAMQSDILGASALGIRNILCLSGDHQKFGDHPQA
KGVFDIDSMQLIGMIKQMRDEGTFLSGAEIAAPPKLFIGAAANPFADPFEWRVFRLEKKI
TAGADFIQTQCIYNMKKFKEWLSLADDMGLTEKTRILAGVTPMKSVGMARYMQSNVPGMD
VPEEIVKRLQGVGKGKVAEEGIKIACEQIEELKEMKGVAGVHLMAIEWEHKVPEITERAG
MLPRPTID
>A0A839VFT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbaspirillum sp. Sphag64|TrEMBL
MTSHNFSIEFFPPKTPEGVEKLRVTRAKLAELQPKYFSVTFGAGGSTQQGTLDTVLEILA
EGHQAAPHLSCIGSSRGTLRTILKEYKAHGIKRLVALRGDLPSGYGAVDLSSGEFRYANE
LVEFIRAETGDWFHIEVGAYPEMHPQARSPQDDVQQFARKVKAGADAAITQYFYNADAYF
HFVEQTRKQGVEIPIVPGIMPITNYSQLMRFSDMCGTEIPRWVRLKLASYGDDTESIRAF
GLDVVTELCERLLKGGAPGLHFYTLNQANATMAIWQRLVD
>A0A7U2I6E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)|TrEMBL
MERITDKINALPDGANYFSLEFFPPKTAMGFANLTTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRALIDEALEQAKVLGIRNILALRGDAPRSEE
YRDEGQTPEQDSNRDFTWAVDLVRYIRKQYGDYFCIGVAAYPEGHSDESHPEHQDPARDL
PSLVEKTKAGADFLMTQLFFDVEAYDKFETMLRNHESGAFKTIPIIPGLMPIQSYKILLR
TTKLSHARLPSDILARLDAVKSDDELVKQVGVQILDEMVEHIKSRPDVGKRGFHFYTLNL
EKAVSHIVEDCDLIPQENMGDEDGVIVETTPAINLEPPQNMLLARERRRRSSVTSGTRNR
VIISHPSATKSNHSYEATEEEAGILRGPINTRASTLAISEGEGSLGREATWDDFPNGRWG
DARSPAFGEIDGYGPTLHVSTTQALKLWGHPVDKQDISALFRKHLEGELEALPWSEQGLS
PETSTIAKQLLALNAKGWWTVASQPAVNGVRSTDPVFGWGPKNGYVFQKPFVEFFLPAAE
FHALRTRLDAHDQVTYFAGNANGDFEASSEESVNPVTWGTFAGKEIVTPTIIEAVSFRSW
LEEAFSIWREWQRIYPTKSASGKLLGQTREDVWLVNVIWGDFVQGDGLWEFLGA
>A0A3M2DB80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRDFLDTLRDAPLLFDGAMGTLLYDRGVMHTRSYDELNLSQPELVAQIHREYLDAGADIL
ETNTFGANRLALAKHGFSDRAAEINAAGARIAREVAGSHAYVAGAIGPTGVKFAVAPDHQ
RRLALDALREQIEALAAAEVDLLLLETFTSILELEAAVALARAHGGGRPVGAQLVFGPDR
RADGGLSPAEVAERLVAAGADFVGANCGAGPPELYDVAVAMVDCGKPVSVQPNAGLPSVI
EGRTIYVANPEHFGVFARRLLKSGVKLVGGCCGTTPEHTRRMMGAVRMMGARPQSARLRE
AATRAAVAASPPKPAVPLAERSRLGARLAAGEFVVSVELNAPAGTDTTRVEAAVRELLAG
GVDIVNIADGPRATARMGNLALCALLRQRTGVEPILHVCTRDRNFLGLVAHLLGAHALGM
RDLVIITGDPPKMGDYPFATPVYDIDSIGLLKLARDLNAGIDPAGRALDGQTAFVLATGA
EPGAADYERELRRLEAKVAAGAELVMTQPVYDARTLERFLDDVAPLGVPVMVGLLPLASH
RNAEFLHTQVPGMSIPDAYRARMARVGSGPAARAEGVAIAREVLAAVKHRVAGAYIMPPF
NRVDSALAILDEVRGDRWTPAPPPDRADA
>A0A6M4IU65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonas groenlandica|TrEMBL
MSATEHPTNTPDTANGATDARPRAALLARLLDPEQVIMFDGAMGTMLYARGVFINQCYDE
LVLRSPDLVREIHAAYVKAGAEVLETNTFGANRAKLTQYGLEGQVTAINTKAAQLAREAA
GDHRLVSGAVGPLGVRLEPYGPTSKDEARGLFREQMLALKAGGADCFLLETFTDLEELEQ
AILAAREVDAGMPVIAQATVGPDLRTSFGASPEDIARVLDRWGVDVIGLNCSVGPQTILE
AIERMAAVTTRKLSAQPNAGMPRDVGGRSMYMASPEYMATYARHLIQAGAKIVGGCCGTT
PDHIKAMVEGVRPLAPRTRVIVAHDGTGAVRDEPVGRAQVPLDQRSRFGAKIANGQFVTS
VEIVPPRGVDTVKLELDAAALHKAGVDAINVPDGPRAQSRMGAIATSLIIERHGIEAVTH
YCCRDRNLLGMLSDLLGASALGLRNMLLITGDPPKMGPYPDATAVFDIDAIGLTNLVSKL
NRGLDPGNNPIGEPTRFVVGVGVNPAAIDPAHELKRFHWKVEAGAEYAITQPVFDPAQLE
YFLTSIDDVRIPIVAGIWPLVSARNAEFLANEVPGVTVPKEVLDRMRKANDKSKEHALAE
GIAIARESLERVRGSVQGVQVSAPFGRIELALEVFG
>A0A7C5MFU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Solibacter sp|TrEMBL
MSSNRSKEFLQLLSQRALVADGAMGTMLYSKGVFINRCYDELNLSNPALVKEVHLEYVKA
GAEILETNTFGANRARLASFGLAEQLRAINHAGVRLAREAAAGAAFVAGSVGPLGLRIEP
LGPTSFEEARAMFREQIEALLEAGVDLIILETFASLSELREAVFAAREAAGPDLPLVAQV
TIDDAGNMPDGASTETFSRRLDEWPVDVAGCNCSAGPKVMLETIEKMKQYTSKPLSAMPN
AGHPARVEGRQIYLCSPEYMAQYARRFLWAGVRIIGGCCGTTPEHIKLIKNEARSLQPGH
AHAEVAVEEPAAKAESMAPVPLAQKSKLGAKLAAGQFVTFVEIVPPRGVDASRELAGAKL
CAEHGIDCINVPDGPRASARMSAQVTCQLIQQHAGIEAVLHFCCRDRNILGIQSELLGAH
AVGIRNLICITGDPPRMGAYPAATAVFDVDSIGLVHIVSNLNRGLDIGGNPMGSQTSLVI
GVGANPGALNFEEEMRRFEWKVQAGAEYAVTQPVFDVDLLERFLRRAERFRIPIIAGIWP
LLSYRNAEFMVNELNVPVPAEYMERMRRADTTEKARREGVEIARDLVRRIAGMVAGVQLS
APFGRYELAIQVAEAVPHRSAQARPSARP
>A0A357BNR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MHTLKDSLSSKKFTITAEICPPKGTDVSDFLKKAQLLKDKIAAANVTDNQRAVMRLSSLA
CSVLLLKQGLDPVFQMTCRDRNRIAIQSDIMGAWTLGVKNILALSGDHVSFGDHREAKAV
FDLDSVQLVQVINKLNSGTNMKETPLKGGTGFFIGAVVAPEAEPWEPEMIKFEKKIEAGA
RFFQTQAIYDIDKFHKFYEYARKFDVKILGGILLLKSAKMAHFLNTNVPGVTVPKHLIDE
LEKAKDQLEKGIEIAARQVKELKKFCDGAHIMAIGQEESVVKIIEGAG
>A0A7V2YCX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSRTSHLQEVLEGAHFAVTAECGPPKGADPQTLREKAQALKGYVDAVNVTDNQTAVVRLC
SLASCAILKQMGLDPVLQMTTRDRNRIALQSDLLGASALGIGNVLCLSGDHVSFGSEPQA
LGVFDLDSVQLLYTARLMRDQGKFLGGGVLSDPPRLFLGAVENPFADPLSFRAKRLAKKV
AAGAQFIQTQCVYNLERFEEWMKQVQDLGLQEKTHILAGVTPLKSARMARYMKERVAGMD
LPDPLVQRMERTPAPKQREEGLRIALETIEALKNIPGVRGIHIMAIEWEEVVPVLVEKSG
LLPRPLT
>A0A7V3W0J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MPIPFAEALRTKEFVVTAEIGPPKGVDIDEMLHHIDLLKDKVDALNVTDNQSSVMRIGSL
PVCKLIKEAGGEPILQMTCRDRNRLALQSELLGAYVLGIRNVLALTGDYITVGDHPEAKP
VFDLDSVLLVKLIKQLEQGRDFAGNELKGAPKFCVGAIVTPEADPIEPQLLKFEKKIKAG
A
>A0A7V2DHY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKIKDLLQKETFIFSFEIFPPMRDGNITELFATIEELVEVEPNFISVTYGAGGGTQDMTF
EIASRIKNRVETEVLTHLTCVQATEKDILEILDHLERENIRNILALRGDPPQGKEKFTKA
AGGFGYANELVEFIRTHGDFSIGVAGYPECHTEAPDLDTDIQNLKKKVDAGADFIITQLF
FNNDDFYRFRDKAVSQGITVPIIPGIFPIFNFKQIAKIASLCGATIPKPLFDQLSAVRDR
SDEVAHYGVDYAIRQSEDLLGNDIPGLHFYSMNKSNHVTHIIRQLSINRKVHYEGEKRTT
GGTLHAPH
>A0A7V3RVS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTPFSHLQQVLESRTFAVTSECGPPKGADPSSLVRKASLLKGYVDAVNVTDNQTAVVRLC
SLASCAILRQMGLDAVVQITTRDRNRIALQSDLLGASALGIRNVLCLSGDHVCFGNEPGA
MAVFDLDSVQLLEVARKMRDQGSLCSGDPLTSPPKFFIGAVENPFADPMDFRVKRLEKKV
KAGAQFIQTQCVYNIQRFREWMERVRDRGLDERVHILAGVTPLKSAKMAHYMREKVAGMD
VPEELVRRMSSLPAKDQRAEGMEIALEIIEALREIPGVRGIHLMAVEWEEAVPELVTRAK
LTPRPSPQGEI
>A0A0S8CNF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium SG8_51_3|TrEMBL
MSIVDMVKKGKFVATAEVGPPKGIEIQEMLETAEMLRDKVDAINATDQQSSAMRLGSLAT
CCILKQKGLEPVLQITCRDRNRIALQSDLLSAHVLGIENVLCLTGDHVSLGDHPQAKPVF
DLDSVSLLQAAKELEQGKDLAGKELVGSPKFCLGAVVSPASEPVEPQIIKMEKKVKAGAQ
FIQTQAVYEPKKFEEFMKAIAYLEVPVMVGIVLLKSAGMARFMNKNVAGVHVPEDLIEEM
DGAEDKPKKSIEIAARLIKEMKSMCQGVHIMAIGWERKVPEVLSAAGL
>A0A3A5ADU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSAETPSKLQKMINAGHLAVTSEVGPPRSADGAIIEHKAKMIKDYVDAINVTDNQTSVCR
LCSLAACIRIKQMGLEPVLQMVTRDRNRIAMQSDILGAASFGINNILCLTGDHQHFGDHS
SCANVFDLDSTQLAMCVRMMRDEGKLLGGFEFQVRPQMYIGAAANPFAGPNVALRVSRLA
KKVAAGVQFVQTQCIYNMDTFKTFMKMMVDRGLHEKVAILAGITPMKNVGMAKYMKNRVP
GIDVPDAIVQRMGGVPKEKQAEEGINLAVEQIEELKEVEGIRGFHIMAIEWEEKVPEIVQ
RTGLYPRPQLPD
>A0A661KW58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTEYKSGSNLEKVLKAGHFAFTGECGPPRGANVEVVRKKAQYLKGCVDAVNVTDNQTAVV
RMSSWAACLILKEEGLDPNFQMVCRDRNRLAMQSDILGVSAHGIKNMLCLSGDHQRFGDH
PEAKNVYDIDSIQLISMVKKMRDEGKFLNGEPIDVPPKLFIGAACNPFAEPLEFRVYRLA
KKIAAGADFIQTQCIYNMKRFREFMKRVVDMGLHEKCYILAGITPLKSVGMARYMATQVP
GMDVPEELIKRLKEAGKKKAAEEGIKIAVEQIQELKEMEGVAGVHLMAIEWEHRVPEIAK
LAGMLPRPKVE
>A0A3N5PEF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MISGSNLEQVLISGQFTVTGELGPPQNGNFDVVRDKARILKGHVDAVNITDCQTAIVRMS
SLTAGLIALAEGVEPVMQMTCRDRNRIGIQSDILGASALGIKNLLCLTGDHQKFGNHPQA
KGVFDMDSIQLLGMVKTMRDDKKFQCGDEIKSHEPRLFLGAAANPFADPFEYRPIRVGKK
VEAGASFIQTQIIYNVEKFARFMEIVRDLGLHEKVYILAGVTPPKSVGMARYMKKFVPGL
DVTDEVIERLKGAKDPKEEGINICVDIIKQVREIPGVAGVHVMAIEWEQAVPEIVSLAGL
SPRPGAKTVEPRLRSSEAIELIVSNAKEDAKAEIEKAALEQAQASRDLVAKEKEKITSEI
SSLKRQTEEAKAIAGQKETEIKRLTEELAKTKAGQGHAQAAKGLAANRESIALSSREGRA
LTSVRSGLEALRKGLGINEDQLEALRRFFEAEFLLHSDTVEQVTVPFYEAAAIREKLEKP
EAETRHKEVVNLVAKGNVLLHKNDAAGALDAFEKALAIEPGDQKAGEGLKKAREALEIAA
LAEKEAAPAVPEGVPPCPEGLSPEEWQRKWVIRFVATGNVCLHKGDVDGASKAFKLALKL
KPDDEKAKAGLLKAESGGVTPVTVPAEPEVPEKAEVQPTPESKTAPV
>A0A661MKF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEYKSGSNLEKVLKAGHFAFTGECGPPQGANVEKLREKAQHLKGMVDAVNVTDNQTAVV
RMSSWAASLILLQEGLEPNFQMVCRDRNRLAIQSDILGVYSHGIRNMLCLSGDHQKFGNH
PQAKNVYDIDSMQLIHAVKTMRDEGKFLNGEQIDVPPKLFIGAACNPFADPFEFRVYRLA
KKIEAGADFIQTQCIYNMDKFREFMKRVVDMGLHEKCYILAGVTPMKSVGMARYMAKQVP
GMDVPDSLIKRLQGAGKGKAAEEGIRFAIEQIEEFKEMEGIAGVHLMAIEWEHRVPEIAE
RAGMLPRPKV
>M6Q7H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira weilii str. UI 13098|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPDGDLKLMETVKELALLDPDFVTVTYGAGGSTRDK
TVQILSEISKRYSFPTVSHFTCVGANQDQIFKALEEIRSSEIVNLMALRGDPPKGEGKFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPDAKSLEEDVENLKRKVDAGTDFLVS
QLFFVNSIFENFLNLVRKAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A1L7TD67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium mangiferae|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFRYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIHDIALLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAADTEPIANGTAATAVAN
>A0A3A5APV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKVTELWQKKKPTISFEFFPARNAEAAEKLNKVIDQLIMMGPDFVSVTFGAGGSTREGSR
QLVDRLKHELKQEVMAYFAGFGLGPDDIQGVLDSYLNLGMDNVLVVRGDPPHGQPDFKPH
PASLPHASDLMEYIRPRYPFCLGVAGYPEGHIEAESKEKDLEYLKLKVDKGAEYIITNYF
YDNRFYFDFVDNCHKLGITVPILPGVMPIFSIKMMDTLAKLCGASISGELRQKLAALPAG
DNQALLAFGIDFAAAQCKELIVAGAPGLHFYTMDRSHSTAGVLARLRREGVL
>A0A3A4R5Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNNSSKLKRVLEGGGFAVTAECGPPKGANSDVVLKKAEMLRNKVDAVNVTDNQTAIVRMS
SIAACSLLKTAGLDPVLQMVVRDRNRIALQSDILGASALGIRNVLCLSGDHHIFGNQPQA
MGVFDLDSIQFVQVVKMMRDEGKILGGDDLSQPPDLFIGAAANPFADPFDFRVIRLAKKI
RAGADFIQTQCIYNLYRFERWMGMARDMGLTDKAYILGGVTPLKSPGMAKYMKTKVSGMD
IPDELIKRMEGVPKDKQREEGINICVETIQRLREVPGIKGVHIMAIEWEEVVGEIAERAG
LLPRPVFG
>A0A225DUU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fimbriiglobus ruber|TrEMBL
MHIQDIFREHPTTFSFEFFPPKTDEASEELFHNVARLQQLKPSFVSVTYGAGGSTRDRTH
DLIIRIQRETDLTAVSHLTCVCHTLDEMTAILDRYAGSGIENVLALGGDLPRDRANYDRA
RDAFQYADGLVGFVRSRTNAPDRRGFGIGVAGFPEGHPGTPNRLKEMDYLKRKVDAGADY
ICTQLFFDNRDFYDFRERCELAGIKVPIVAGIMPVASKAGMVRMADLAAGARFPAKLLRA
VERCGKDDAAVARVGVHWATEQCLDLLENRVRGIHFYTLNKSDATRQIYDNLGVVDSVAL
RA
>B3QV58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroherpeton thalassium (strain ATCC 35110 / GB-78)|TrEMBL
MIIKDLLQPDKTQFSFEFYPPKKDEEWEKLFFHISELMPMNPAYVSVTYGAGGSTRDKTH
NLVVRISKETNIPVVSHLTCVGSSKSEIHTILERYAENGITNILALRGDPPKGSTTFEKP
ADGFAYANELVAFIKKNFPQIGVGVAGFPEGHPETLNRLTEIDHLKEKVDAGADYIVTQL
FFENRDFYDFRERCEIAGIHVPICAGIMPITTDKGMQRMAELSPGTRFPAPLLREISKAQ
NDEEVSAIGLNWAIAQVRDLIENKTPNIHLYTLNHSRPTLKIFEALSEKNPISS
>I4VVC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter spathiphylli B39|TrEMBL
MPSISFEFFPPKTDEQRAQLDRAAQVLKAHQPEYASVTFGAGGSTLSYTGDTVARLHAQH
GLPVAPHLSCMGGTKAEITELLDGYRAAGYRRLVALRGDMPSGMATAGDFRYAAELVAFI
RAHCGDHFHIEVAAYPETHPQADDALRDLQHFKAKIDAGANGAITQYFFNPDAYFRFVDD
VRKLGVDVPIVPGIMPITNFSQLRRFSEMCGAEIPRWISKRMQAHGDDADAVRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRARATQAVLQQLS
>A0A661L121|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSETKTPSKLEKILSLGHLAVTSECGPPRGSDPEVIRKKAEMIKDYVDAINITDNQTSVT
RLCSLASCIHLKLMGLEPILQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQKFGDN
PQGQNVFDIDSMQLIQMVRLMRDEGKFLGGDQIQRPPKMFVGAAANPFADPFEIRVPRLA
KKIAAGAEFIQTQCIYNLDKFELWLKQARDRGLHEKVYILAGLTPLKSAGMAKYMKNRVP
GMDVPDEVVKRMSGVPKEKQPEEGIKICVESIERLKEVEGVSGFHIMAIEWEEKVPEIVD
RSGLYPRPKLDD
>A0A661QY59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTESRLERVLASGAMAVTSEVGPPRGVDAEIVRTKANMIKDHVDGINVTDNQTAMVRMS
SMAAGVIIKQMGLDPIIQMVTRDRNRLAMQSEVIGAAAFGIDTMLCLSGDHPKFGDHPQA
KGVYDID
>A0A1S6FDK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. LM6|TrEMBL
MGHLLMHPAQPRAAGNITHAYSLEVSAKDMPALSAAAPRIAPASTIAIPYLPREDNAARL
AAARIVRTLGFEPMPHLSARRIASFAEFESFIRRAVAEAGVERCFVIAGDPSTAMGPFSD
SAALIDTGVFERAGMQVIGVGGHPEGHPVMSKAEQWDVLERKCRSIEQRGMTPLIVTQFA
FDADIVLTWLKALRERGIDHPVRVGVPGPASIAVLARYAALCGVSACASMWSKYGVSIGK
LFGTAGPDLFVERLTAGLTAAHGKVSLHFFPFGGIAQSVKWIEQYRFRTAPAPG
>A0A1Z8UHC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium TMED56|TrEMBL
MGITIPILPGLLPILSLAQVKRFCSMCGAGLPVELENQLNEANEDEHPKIGSEWATQQVR
SLLKKGAPGFHIYALNKSKSTVNILQSLQN
>A0A1C6JJT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Flavonifractor sp|TrEMBL
MKIAELFGKGKTVFSCEVFPPKKTSPVDSIYKTLDGLKDIRPDFISVTYGAGGSSAVNQS
TQEIASIIQNQYHITAMAHLTCVACTRGEAAELLAGLKRNGVENVLALRGDRNPDFPPKT
DFLHADELVSFIHRRGDFGVSGACYPEGHPESPDMIHDIRYLKQKVDAGAQHLVSQLFFD
NDDFYRFVERCRIAGINVPIEAGIMPVLNKGSIERMVSMCGASMPRKLTRILARYGDHPQ
AMREAGMAYAIDQIADLIASGVDGVHLYTMNNPAVARQISDSVASIRTV
>A0A1T1AQV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax fermentans|TrEMBL
MTASSRLPVSIEFFPPKTPEGVEKLRLVRQALYALKPEFCSVTFGAGGSTQEGTFNTVRD
ILAEGASAASHLSCIGATRAGVREQLATLQAMGVKRLVALRGDLPSGYGAGGEFQYASDL
VAFIRAETGDRFHIEVAAYPEIHPQAKSPESDLQAFASKVQAGANSAITQYFYSADAYFR
FVEDADALGVQVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIKAFG
LDVVTDLCEQLRAGGAPSLHFYTMNQSAAVLEICDRLGL
>Q0UB79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)|TrEMBL
MNRALIDEALEQAKVLGIRNILALRGDAPRSEEYRDEGQTPEQDSNRDFTWAVDLVRYIR
KQYGDYFCIGVAAYPEGHSDESHPEHQDPARDLPSLVEKTKAGADFLMTQLFFDVEAYDK
FETMLRNHESGAFKTIPIIPGLMPIQSYKILLRTTKLSHARLPSDILARLDAVKSDDELV
KQVGVQILDEMVEHIKSRPDVGQERENMGDEDGVIVETTPAINLEPPQNMLLARERRRRS
SVTSGTRNRVIISHPSATKSNHSYEATEEEAGILRGPINTRASTLAISEGEGSLGREATW
DDFPNGRWGDARSPAFGEIDGYGPTLHVSTTQALKLWGHPVDKQDISALFRKHLEGELEA
LPWSEQGLSPETSTIAKQLLALNAKGWWTVASQPAVNGVRSTDPVFGWGPKNGYVFQKPF
VEFFLPAAEFHALRTRLDAHDQVTYFAGNANGDFEASSEESVNPVTWGTFAGKEIVTPTI
IEAVSFRSWLEEAFSIWREWQRIYPTKSASGKLLGQTREDVWLVNVIWGDFVQGDGLWEF
LGA
>A0A661JDW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
IVLLASVGMARYMNANVPGIFVPEEMIQELASAPKGKAIEKGIEIAARLIRTIRDEGICD
GVHIMAIGREERVLDILDAAGL
>A0A1S6F1H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. LM6|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRVKLSELHPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRESIRAVLADFKAAGVNRIVALRGDLPSGYGASGEFRYANELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLNAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A0J6WQH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera cerevisiae DSM 20462|TrEMBL
MHTNNLFAQKTVFSFEVFPPKRDMPLTAIYETLRALSSLRPDFISVTCGANGQGGNRTVE
VAAAIKNQYHCETAAHMPCIYLTEKEARQTLEALHQNRIENILVLRGDQTPGREPAHVFE
YASDLISFIKKEAPNFNIIGACYPEGHLESKTPAADIRHLKEKVDAGADELISQLFFDNS
LFYRFLERCEIAGIQVPIEAGIMPVTNQKQIERMVTMCGATLPIKFQRAIAKYGSNPAAI
QDIGIAYAVDQIADLLANGVDGIHVYTMNNPYIAQKITAAVKNLL
>A0A660R568|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotogae bacterium|TrEMBL
MREALEKSKGVILEVLTPRGSNLRKFLEFTEKMWETGIDAFSVTDMPLGKVRMAPWAGAH
FLLERNMDVLIHFTRTTRNMIRIQSDLLGSYALGVKNLLILSGDDPKHGDYPNTTRVDDI
SITDLIKLAKSLNDGKDLGGRTIKPSTDFYVGAVFNHRDNTDLVKAKEKIRAGADFLISQ
PVFDVKEVENVIYELNEVKLVLSVVFFKSEKQFKIFSQVPGVNIPRKYLEDLENKSDEYI
RDYTLSKVLEIVDTLKSKVDGFYVVGIVRDIESVRRLVEIAKGG
>A0A534Z733|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKITDILARGGPCISFEFFPPKTPEGEAALMRTIEALKPLGPGFVSVTRTGAKPREAPVE
LVTRIRALGIEAAAHVTCIEAGREELAAHYELIEARGIENVVAIRGDRPGEGSFHPPLNG
FRYAVDMIRFVRARGHKLCLVGGGHPEGHPECRDLELNIQHLKMKVDAGLDAVITQLFYD
NADYFAFVERARRAGIGVPLVPGIMPITNVPQIERITALSGNQIPAALRAALERVRDDEQ
AALAVGVEWATRQCAELLRSGAPGIHFYTLNKSPATRAIFENLCREGLVGGPLPRLATPS
PIR
>A0A1I2I0L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavimobilis marinus|TrEMBL
MAASASASPTPPDPTAQRPTISFELMPPRNPAAAPKFWETARRLLEAKPDFVSVTYGAAG
QDRATSTAVLEALVRDVPALPIAHLTCVGTTREEMREVVRDFLSRGVRSFLALRGDPPAD
QPSWRPTPDGVASSVELVALLREVEAERCEQNAAAALRGAARPLTIAVAAFPGGNPAART
SPEQEVARLKDKQDAGASFAITQLFYEPATYTGFVAAARAAGVTIPILAGLLPATDPTRL
ARVEALTGVAAPRDLVADLERLTDPAERHARGVRASVELASAVLDAGAPGLHIYTFNQHK
AALDLLEGVHLGGGSARPAPAGVTAPDLARGPWVVPATTRPTIQGAPA
>W0F3M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niabella soli DSM 19437|TrEMBL
MKVIDHIKNAKDTLVSFEILPPLKGKGIEALYDHLDPLMGFKPAFINVTYHRSEHIFKRN
PDGSFKKVEVRKRPGTESICAAIMNKYNVDTVPHLICGGFSINETEDALINLNYLGIDNV
LVLRGDAAKSETAFIPQPDGHKYANELLKQVVGLNNGIYLEEDLKSSRKTDFCIGVAGYP
EKHFEAPNMETDLNYLKEKVAAGADYIVTQMFFDNAKYYAFVAACRNAGITVPIIPGLKP
VYSIKQLNILPKTFHIDLPTDLSKEMMKCKTNEDVEKVGEEWLLMQSKDLKKNGVPVLHY
YTLGRPQIVANVVKEVF
>A0A2D4TGK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKIADLYQKKTFVFSIEIFPPKNTESLERLKLRLEEFKSYHPDFISVTYGAGGSTRENTH
ELASFIQNDLGIETMAHLTCVSHTRQEIEEVLEQFHQSGIENLMALRGDPPSGGKCFQRP
SGGFAYAVELIQAVRSLNGFCIGAAGYPEGHVENPDKEADLRHQLAKVDAGADLLVSQFF
LENEHFLKWRDRLRREGVEIPIIPGLLLPSSPDALFRMEELCGVLIPLSLRQKLERFAGD
PNALKEIGWLHLAEQTEALIGEGIEGVHLYALNCLETIRRFSELIQPSFSFQPTYPEDPT
RRSFTEKTEMHGTA
>A0A1A9RTU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eikenella corrodens|TrEMBL
MLHNTLSFEFFPTRTPEGREKQKITRKQLSQYQPEFFSCTSGAGGTTREGTMQTIRDILA
EGMAAAPHIPCVGLDAGELTDLLQEYKDLGIRHVVALRGDIPSGMGLGTTGLHHANELVE
LIRHRFGDWFHIEVAAYPEYHPQSRSAEDDIQSFVRKVKAGADSAITQFFFNADAYFRFF
DDVRGRGVEIPIVPGIMPIANFSKLARFADMCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCGRLLRHGAPGLHFYTLNQAGLSSTICQRLGY
>A0A3N5SJC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGGQEKIEGEIAFFVGATVNPSADPLEAHVIRLAKKVKAGADFIQTPCVYDMDRFQEWMK
RVRDQGIDRKAPLLIGVMPLKSGQMGRDIRKKFPGALIPEGLIERLDRAGNPEEEGIKLC
IEQIAILKAT
>A0A661Q703|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKSGSNLEKVLTAGHFAFTGEVGPPRGANVEVIRKKAAFLKGNVDMANMTDNQTAMVRMS
SWAGSMILLQEGVEPNYQMVCRDRNRIAMQSDVLGAYAHGIRNMLCLSGDHQQFGDHPNS
KGVYDIDSVQLIGMVKKMRDEKTFLGGDKLDEAPEMFIGAAANPFGQPFEWRVHRLAKKV
AAGADFIQTQCIFNMERMREWIHQANDMGLTEKVYILAGVTPMKSVG
>A0A534QSY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
VGVEWATRQCAELLRSGAPGIHFYTLNKSPATRAIFENLCREGLVGGPLPRLATPSPIR
>A0A661KW70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MTEYKSGSNLEKVLKAGHFAFTGECGPPRGANVELVRKKAQHLKGCVDAVNITDNQTAVV
RMSSWAASLILKEEGLDPNFQMVCRDRNRLAMQSDILGVSAHGIKNMLCLSGDHQRFGDH
PEAKNVYDIDSIQLISMVKKMRDEGRFLNNEEIDTPPRLFIGAASNPFAEPVEFRVYRLA
KKIAAGADFIQTQCIYNMERFREFMKRVVDMGLHEKCYILAGITPLKSVGMARYMATQVP
GMDVPQELIKRLRGAGKGKVAEEGIKIAVEQIQELKEMEGVAGVHLMAIEWEHRVPEIAE
RAGMLPRPEV
>A0A661STC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MRVTDLYGSKKPVISMEFFPPRNEKAAEAFGSIIDDLAELKPDYMSITFGAGGSTRDGSY
QTVKQLMLDKNLPTVAYIAGYGLGPDELTDVLDKYKELGVETIFVIRGDKPGGDDFTPHP
DSFSYASDLIAFIKERYDFTLGCAGYPEGHIDSESLEKDIEYLKLKVDNGAEYVVAQYFY
DNLYFSEYVEKCRAVGIHVPIIPGIMPIYTVKLTKILSEVCGSTITDTLQSKLEAVDAGD
KDAVLNLGIDFATEQCRGLLKEGVSGLHFYTMDRSKSTSEIINRLKQENLL
>A0A7W1SJC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MRTLRDLLSDGRVHVADGAMGTMLYGRGVFLNVCYDELNLKQPDLVKEIHREYVRAGAEL
LETNTFGANPVKLATHGLAADVERINSVAAGIAREAAGERAAVVGAIGPLGVRIEPFGEM
SVDDARHVFGRQVRGLLAGGVDGFILETFSDVSELGAALAAVREQCDLPVIAQMTVGTDG
KTHYGTDPLVFGPTLAAMGADVIGVNCSVGPHGVLEAIEKLAKVVTVPLSAQPNAGLPRE
VGDRKIYMASPEYMASYARRIVEAGARFVGGCCGTTPEHIRAIVGFVHSVSPRHGSTVAA
APLPATAVDPVPLAERSRLGAKLSEGRFITTVEIVPPKGVDPGPMFEQVRQLKEAGVDAV
NVPDGPRAQSRMGALLSALMIEREVGIETVVHYACRDRNLLGMLSDLLGAAAAGIRNLLI
VTGDPPKMGPYPEATAVFDIDSIGLANLVSRLNRGLDPGGNPIGQPTRFVVGVGVNPAAH
DLDRELRRFAWKVEAGAEFAITQPVFDLAQLDRFLARVESFRIPVVAGIWPLVSLRNAEF
LANEVPGVSVPDSVLDRMRCASALGKEAALAEGVRISREMLGAVAERVQGVQVSAPMGRV
PVALEVLAGAPIEPATAREYTPRT
>A0A645F320|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MAGIVPLKSPGMAKFMTANVPGIFVPDDQIERLKAAGKGNYVQEGIKMAGEFIKQLKEEN
LCDGVHIMAIGAEENVPKILDEAGL
>A0A7X4C2P0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MSGRLREWIAGDGVHLLDGAMGTVLYESGVFVNQCYDELNLSEPDLVLGVHADYVRAGAE
LIETNTFGANPVKLEPFGLEPSVHEINVRAARLARQAAGGRAEVLGAIGPLGIRIEPWGP
TSVDEAADLFGRQVAGLAEGGVDGFMLETFSDLDELLQAVRAVRRVAGDAPVFAQMTFGD
AGHTEYGATIEAAAAALEGAGADVIGLNCSVGPSSMLLGVERMVAATSRPVSASPNAGLP
RDIGDRKIYLASPEYMARYARRMVETGARFVGGCCGTSPEHTRLTATLLGTDGPGPARVS
VSSPSDAGGREAAEPPPLADRSALGRRLARGEFVGAAELTPPHGWDPGELVAGAARLRDA
GVHTVHIVDGPAHRSRVASLPAAIVVERELGMETVPHYSCRDRNMLGMLSDLLGAAAAGL
RNVFLITGDPPRGGPYDTGGVYDIDSIGLTNIVRQLNLGLDPGGSSIGAPTSFVKGVAVN
PGAVDPEEEIRRFAWKAEAGADFAVTQPIFDLENFLAFAREIEGFGVPLLVGLWPPLSLE
NAEFLAHEVPGVDVPLEVLERMAGAQAHGVEAAAREGVAVAREVLDAIRPHVAGALVSTP
GNEVDRAAAVLAEL
>A0A6B8GQF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSAPTSLRVQAFLDAFSLEVSARAMPALGAEATRIPRGTTISIPWLASEDDDARLAAARR
VRELGFEPMPHLSARCIGSRAVLERFLQRAANEAGVAQCLVIAGDLATPAGPFADSASII
ESGLLERAGIKVVAIGGHPDGHPVLGSDACWQVLEHKCQSIEARGMAPMIITQFAFDADI
VLAWLHALRARGIHVPVLVGVPGPASIARLVRYAAMCGVRASALMLSRYGISIGRLLGSA
GPEVFVDRLAGDLTDAHGLVSPHFFPFGGIAQSLDWIKQHRALPSVARR
>A0A1H0KFZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus equinus|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPEKVLAIHKAYIDAGADVIQT
NTYAAKRHRLSGYGFDDKVKEINQAGVRIARQAAGEDTFVLGTVGALRGLKQCDLTLDEI
IQETLEQVGYLLETKEIDGLLFETYYDEEEIIEVLKAVRPLTDLPIITNISLHEAGITEN
GRPLVEIFGKLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLAVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAIKGLKPVTRKFVTP
MVEEAELIKAVKQSETIVDKVKRKVTIIAELDPPKTLDIKKFTEGVKALDEAGISAITLA
DNSLAKTRICNVSIASLLKDEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIKQLNKGKGYSGASIKKETTFTAAAAFNPNVKNLS
RCGRLIERKIAAGADCFITQPIFNSEIIENLADLTRDYETPFFVGIMPITSYNNAVFLHN
EVPGIQLSDDFLAKLEAVKDDKEKCQRLALEESKALIDHALEFFNGIYLITPFMRYDLTV
ELIDYIHQKVEQRNQIIS
>A0A7W1BE12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
AREAAGERAAVAGAIGPLGVRLEPFGETSVDEARQAFRSQVQGLLDGGVDSFILETFSDV
AELGAALGAVRELCDLPVIAQMTVGTDGKTHYGTDPVVFGPTIQALGADVIGVNCSVGPH
GVLEAIEKLARVVTVPLSAQPNAGLPREVGDRKIYMASPEYMASYARRMVEAGARLVGGC
CGTTPDHIRAMVGYVQSVSPRHTTTVAAIPVPATTPEAVPLAQRSRIGAKLAEGRFITTV
EIVPPKGVDPTPMFEQVRRLKAAGVDAVNVPDGPRAQSRMGALLSALMIEREVGLETVVH
YACRDRNLLGMLSDLLGAAAAGIRNLLIVTGDPPKMGPYPEATAVFDIDSIGLTNLVSRL
NRGLDPGSNPIGQPTKFVIGVGVNPAAPDFERELKRFAWKVEAGAEWAITQPVFDLDQLD
RFLSRVESFRIPIVAGIWPLVSLRNAEFLANEVPGVTVPDAVLERMRRASALGKDAALAE
GVRISQEMLTAVADRLQGAQVSAPLGKVPVALEVLEAAPIEPVASPGYTHDT
>A0A7W1KKE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
MPTLDDLIADKRVHVLDGAMGTMLYNRGMFVNVSYDGLNLTQPGLVQEVHEAYVQAGAEI
LETNTFGANPVKLSSHGLDDETEAINRAAVTIARRAANGRALVVGAIGPLGIRLEPWGPT
AREEAIGLFSRQVRGLLDGEVDGFILETFSDLHEVEAALCAVRALSELPVMAQMTVGHDG
STSYGTTVETIGSRLAELGADVIGLNCSVGPAAMLDALERLVERTNRPLSAQPNAGLPRA
VDDRRMYLASPEYMGSYARRMIQAGARFVGGCCGTTPDHIRKIHDYVASLQPRRISVGRA
PEGPAGPAGVEEVPLGQRSELGRKLGAGELVTTVEILPPKGWNPADMIEQCRMLQAAGVD
AVNILDSARAQSRMGVLPAALIVQREVGLETVFHYTCRDRNMLGMLSDLLGAAAGGLRNV
LIVTGDPPAMGPYPDSTAVFDIDSIGLTNLVQRLNQGLDPGGNPIGEPTRFVVGVALNQG
ADLEHELERFAWKVEAGADFAVTQPVFDAEQLQRFLSRVRAPIPVIAGIWPLASLRNAEF
LANEVPGVQVPPAVLERMRLAQEQGTSAARAEGVAIAAEMVEAIRGVVQGVQVTAPAGRI
GPALEVLACLKAKA
>A0A4T1DUL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MSARTPDRAEAFINAFSLEVSAKTMPALRAEAARIAPGTTISIPYLASEDDDARLAAART
VRELGFEPMPHLSARRIGSRAALERFMERAASEAGVAKCLLIAGDLSTPAGPYADSTSII
ETGLLERCGIKVVAMGGHPEGHPVMNAEDRWRVLERKCQAIEARGMAPLIISQFGFDAGV
VLAWLDALRARGITAPVLVGVPGPASIARLLRYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFVDRLVNGLENTHGQVSPHLFPFGGIVPSLEWIEQYRRRASVTGR
>A0A837UY07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia ubonensis|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDRDAIRAFGADV
VTGLCRRLLDAGVPGLHFYTLNSAAATKTICERLGV
>A0A4Z0DJD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAPGSLRAEAFINTFSLEVSAKAMPALRAEAARIARGTTISIPWLASEDDDARLAAART
VRALGFEPMPHLSARRIGSHAALERFLERAASEAGVEQCLVIAGDLATPAGPFADSASII
ETGLLERFGVRVVGIGGHPEGHPVMSSDDRWQALERKCRAIESRGMAPLIITQFAFDADI
VLAWLAVLRARGINVPVLVGVPGPASIARLVRYAAMCGVGASASMLARYGVSIGRLLGTA
GPEVFVDRLVQGLTDAHGLVSPHLFPFGGIAPSLDWIERYRLRSPFPRVRR
>A0A1T5FCA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter psychrophilus|TrEMBL
MTKVTEFIRQAEGRTLFSIEIIPPLKGQNINELLNSIEPLMEFKPPFVDVTYHREELIDR
VGQDGLIERIPVRKRPGTVGICARLMERFHVDAVPHIICGGFTKDETEDVLIDLHYLGID
NVLVLRGDAEKSAGVFKAKQGGHSYASELVKQVHDMNQGKLLNAETEMWPTDFCIGVAGY
PEKHFDATSFDTDYAHLRKKVELGADYIVTQMFFDNQKFFQFVERCRAEGITVPIIPGLK
PLATKKQLTVLADIFHLEFPKELVSEVEKCATDKDVRKVGIEWGIHQCKELMAYGVPVLH
FYTMGKSDNVAQIAREVF
>W3X542|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pestalotiopsis fici (strain W106-1 / CGMCC3.15140)|TrEMBL
MEKITDKIAALPADANYFSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
ASKSLELAEICQRELNLTTCLHLTCTNMSRKQIDGALEDAKALGIRNILALRGDPPRAAE
YQDPNEDPENAIDEGFVWAIDLVRYIKKNYGDYFCIGVAAYPEGHADESHPMGQSLEHDL
PYLVEKTQAGADFIMTQLFFDTDAYEKFERTLREHPSGAFNNVPILPGLMPIQSYQMIKR
TTKLSHARIPDHLMARLDAVKKDDEKVKSVGVDIVSEIIEKVKAIKSRTPGPRGFHFYTL
NLEKAVSFIIERSDLIPPTTPDDLEEEAVVDDLISVPTLQVNGSAHDSTAVASLRRSSRR
HSSIGSDPRNRVIVSDRPLSHPEYETSAADASIPAEPINTRANTLAISEGEGVLGREATW
DDFPNGRWGDARSPAYGEIDGYGPTLHVTNAQALKLWGHPTKREDISNLFVKHLQGELEA
IPWSEEDLNAETNTIAPQLLQLNTKGWWTVASQPAINGLPSTDPTFGWGPTQGFVFQKAF
VEFFVPSAEWKVLYEKLQSSEVQDTVCFYAANAKGDFVSSDMTGGLEGQQVRQASTNAVT
WGVFPGKEIVTPTIIEEVSFRAWSEEAFGIFAEWAKVYGKESESAKLLEGTLQDLWLVNI
IHHDYVEKDALWNLLLN
>A0A4V0E943|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLTDF
IQNDLAIPTIAHLPAIYLTKEKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1Y4DKC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olsenella sp. An270|TrEMBL
MRIADKLAERQTFSFEIFPPKGNLPLEEAYAIASEMAADRPDWISVTYSAGGSGNSANTV
PIAASIERDLGVTALAHLTCLGSARADVDAYVAQLAQAGIENVLALRGDRAPGREPIDFA
HASDLIEHLRASGADLCIGAACYPEGHVESPTEEESFESLYKKQEAGADYLVSQLFFDNE
DFYRFREKCLRHRVRLPIVAGIMPFTSVKQIQRMAFTCGASIPAKVVKRLVLAGDDPADQ
ARAGVEYACEQLCDLAANGVDGCHVYSMNKPSVAHAAREALVACGYLGA
>A0A503QGG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-4-6|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETSLTPAAHMTCVDAARDQVDTVIREFADMGVKRFVALRGDPAAGVGT
SYRPHSDGYANGAELVGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEVEVA
GSAAA
>R7DFP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella sp. CAG:51|TrEMBL
MSMKVIDLIKNSPTTAFSFEVLPPLKGNSIEKVFNTIDTLREFDPKYINITTHRSEFLYK
DMEGGLYKRVAVRTRPGTVAVAAAIQNKYQIPAVPHIICSGFTQSETEYALIDLSFLGIC
DLLILRGDKAKHENRFIPTPEGHAHAIDLQAQVNRFNEGYFLDGSKMSLINTPFSYGVAG
YPEKHDEAPNPDSDLFWLKEKVKAGAEYIVTQMFFDNEKYFSFVDRCKSEGIDVPIIPGI
KPINFRNQLTVLPKVFHVDLPEALASELRKCKTDEEAKEVGVEWCILQAKELKEKGVPSI
HFYSMMATESVKRVARQVY
>A0A365D520|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. AG30|TrEMBL
MSPPSLIEAHPNLSDTAPVALSYELFPPRSPAAAETLWTTIRELETTAPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELAGIIGELLDIGVRGILALRGDLPKD
GVRPSDGALRYAQDLIELIRRVEQRRSALLCAGKIAVGVAAYPSRHPESPSEEHDVEVLL
AKQRSGADFAITQVFFETEQYANLLTRARRAGVTIPIIPGVMPLTSLRRLTRLGELAGVE
PAPALMERLAAADSDLERLHIGVDATVDLANAALDAGAPGIHLYTFNEHQSALEVLDKLA
LPRHSRLGTRRDSTARPQLAS
>A0A495AL47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. R1(2018)|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYASDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNYKQAHKFATMTNVRVPHWMAQMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGM
>A0A2J0T2U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYDPQYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKLLQG
>A0A2T7LAK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CS014|TrEMBL
MALGTASTRTDHARTVREMLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A7J5BXQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoclavibacter sp. CFCC 11306|TrEMBL
MTASLQPAADRRPQVARSNDAAVSTGASAEEPIAERRFSASRFGLSGEDAFDDGDDAADA
LHAPAAHITPAWDTLPSVEAPTLSLEVFPARGVPQLRRNVAAVRKLLKLGPDFVTVTYGA
AGSRQEGTKELVTWIAQSGVPTYAHLTCQATSLRELDETIDELLEAGVTGILALRGDARD
DGSGLVLPHATDLIARVSQRAEAAGQRIRIVVAAFPTGHPDSRDLREDAENVARKQQAGA
DFAITQHFFDAEDYARFLDLVAATGATLPIVPGLTPTTTVRRLERISELSGLTPPPALAA
ALGAAPDAQTRRDIAVQNTVELAEKLARAGAPGIQLFTMNDEPTALRVFDALSSSPAGAL
GQNTGREPWLLNTQGPALKAALH
>A0A7J2S0V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Syntrophoarchaeum butanivorans|TrEMBL
MTEAYSDLMRNIKEGKFVFTGELEPEKTTDLTELVESAKKLLGHCVACNVTDNPQSMAYM
SSLVASYVVQRDAGMECVYQLRCSDRNSIALTSDLLGAGALGIKNVLALTGDHTTLGDYP
GAKPVFDLDSGQLVYLIRKMVDEGVDLYGRPIHNPPKFHVGVAGNPNADPLESEILKLKR
KIDAGAEFIQTQVIFDIEVAKTFLKEMERFKVPVLIGIFPLKNYGTADYFDKYIPGVHVP
KDLLAEMKKASEISDKEKRNERYDEINLEYYGDFVHEIAHTTSAAGIHVMAVAYERITPA
LIERAKI
>A0A847K9F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MKYLSKLHQALAEGHFAVTAEIGPPKHASAQGVIRHAQMLQSCVDAANITDCQTAIVRLS
SIAAGAHILGCGVEPIVQMTCRDRNRIAIQADLLGAYSLGMRNLLCLSGDHQKFGNHPSA
KNVYDLDSVQLISLMRRMRDESKFFCGEEIKEHEPRFFIGAVANPFADPFEYRVDRLEKK
IEAGAQFIQTQCVFDMERFERFMEMVRARGLDQRAHILAGVTPLKSWRAARYLQTGVSGM
IVPDTLVERLKNAADPKEGIKVCIEQIRHIKEKVRGVHGVHIMAIAWEEAVPEIAERAGL
LPRPGLQRRAESID
>A0A494TDV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas paeninsulae|TrEMBL
MTLTLNQLEEARRALDAPLFADLAGDANVSFEFFPPKTEKMNETLWEAVRSLEPLAPRFV
SVTYGAGGSTRERTHATVARIVRETSVPAAAHLTCVDASRDEIDEVAREYWAAGVRHIVA
LRGDPSVAGSAFVAHPQGYASAADLVTGLKKIAPFEISVAAYPETHPEAISSASDLDNLK
RKIDAGADRAITQFFFSPEAFFRFRDRARAVGITADIVPGILPVSSVAQTRKIAGVCGTA
IPPWMDRLFEGLDAHPGARQLVAATVAAELCRKLYAGGVRDFHFYTLNRAELSYAICHLL
GIRPHKQAQEQAA
>A0A2P5GLC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Superficieibacter electus|TrEMBL
MSFFHANQREALNQSLAEVQGRINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKDIKERTGLIAAPHLTCIDASRNELRAIAQDYWNNGIRQIVALRGD
LPPDGGRPDMYAADLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCASTGIDVEIVPGILPVSNFKQAKKFADMTNVRIPAWMSQMFN
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAE
>A0A413P8W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. AM49-13BH|TrEMBL
MKYSNTAGLLEERLKSSRINADGAFGTYYAKIYDEGSLPEMANVSAPARVFAIHRAYIEA
GAQIIRTNTFASNTVSLGQDIDDVRNNIRCAVKIAREACEGMGVLVAADIGPIPGENMFD
KEYIENEYVDIVNTFKELGVDIFVFETFPELSFINKAIEAVGDKCFVITQFAINQFGYSS
SGYSARKLIDEAAKNQYIDACGFNCGVGPGHMKKLVQNLINRNDKYFAVLPNAGYPQVVS
GRMVFADNNAGYFAQIMKDMAEEGADIIGGCCGTTPEYIRQMTALTAEVSHSRDIKHDNE
EQGDRTFIDCAFYKGKEGRKLIAVELAPPLGVDDEKIMDAAFLMKKSGVDVLTFPDSPSG
RTRADSILMAEKVSRETGMCVMPHICCRDKNAIAMRSQLLGAHINNINNFLVITGDPIPS
MVRSSVKSVFNFDSVGLMNIISDMNQDQFADKPVIYGGAINQGRVNFKVELARVKKKMEA
GATFFMTQPVFSDEDISRLRQIKEETGARILCGIMPFVSLRNATFMKNEMTGINVTDEIL
ARYSADMTKEEGEETGIQIAREIITKTSDFVDGYYFSFPFNRVHMLEKILNA
>L8G9A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21)|TrEMBL
MHIKDMLNQGEQAGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRHA
QLTCEMVSVAQSVYGLETCMHLTCTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEK
WVATDEGFQYARDLVKYIRKTYGNHFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATF
IVTQMFYDVRNFLDWVRKVRAKGITIPIIPGIMPISTYASFLRRCNHMNAKIPPGWIEVM
EPVKNDDAAVREIGRGLVTDMCRSILESGINHLHFYTMNLAQATRSVLEQLEMLPSEERP
LKQALPWRQSLGLGRRGEDVRPIFWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLKGSNEQNIKLWGEPKSVKDIANVFLRYLNADIESLPWSEAPISNEADVIKNQLVE
LNEHGLLTINSQPAVDGVKSSHPVYGWGPLNGYVYQKAYLELLVAPELIDELLDRIARDP
GVTYYAVTKSGTLRTNAPSDAPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDW
AHCHDASSPSRNVIQRVMETFYLVNIVHNDFHQRDALFSLFEGLTVPNIDKAAEGTAAPG
AAPAPAATGVPATNGDKVEDAPPTIVSNVLPVA
>A0A2V3Y9X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella effluvii|TrEMBL
MLSIYAMIMVIKSEPPNAKVAAALCMWPNRQGDREMKTTDIFAKKPVLSFEVFPPKRTNP
VETIYETLDSLRKLNPDFISVTYGAGGSENCKATTEIASRIKNEYGIESVAHLPCIGLKR
DDVISLLDGFKKAGIDNILALRGDIPEGGRPDGDFEHASDLISFIKEKDEYKDFNVLAAC
YPEGHTESENILTDIRSLKTKVDAGADHLITQLFFDNDCFYRFRERASLAGIHVPVEAGI
MPVTNKKQIERMVSLCGVSLPSKFTAIMERYEHNPEAMRDAGIAYAVDQIVDLIARGVDG
IHLYTMNNPYVAAKIHEAVCRLLAA
>A0A412CDC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megamonas rupellensis|TrEMBL
MTRISVELVPRDVEVLKEEVKTIKEKLSDVDFINIPDLLSCDTRSWDGANIAKAYFDDVV
PHLRAMDFDFTKDLPIKDKLREYNIKEVLVIEGDPPQSMLYQVYPTISTDIIKKFSEEMP
EITVYAGIDQYRSSMKEEEYRIRRKQLAGAKGFFTQPFFDMRYLEMYADLLDGLDIYWGV
SPVLSERSVSYWRNKNNVIFPKDFEPTLEWNIEFARKVIEFARKHNHNVYLMPIKAKIMP
YLEGVFAK
>A0A353NSC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MKVGSNLEKVLASGQFCCTGEIGPVTYSSFDNIDKHAEEMRGKVDSVNFTDNQTAVVRLS
SWAASLRLLQLGMEPNLQMVCRDRNRLAMQSDFLGAYAHGIRNVLCLTGDHQAFGNHPGC
KGVFDLDSVQLIYMLKRLRDDGCFECGAECKVAPKFFIGCAENPFGDPFEFRPIRLEKKV
NAGADFVQTQCILDMERFERFMELCVERGLHDRAYITAGIMPVKSPKMARYMQHGVPGMI
VSEEFCQRLEKAEDAKAEAVQLSVEYINHCQEMKGVAGVHVMAVAWESIVPSVVEKAGLL
PRPTF
>A0A1E3T4P3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sherrisii|TrEMBL
MTSTELGCPKRMEFGPCGGVRPDGQCEMRPGACVFADVVPWSGVVSAPRAVRAPLVLADF
SCTPFDRNDVAATAAVLAPGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWMTLSCRDR
NRVVLEQELRGLHSIGVETVLCVTGDGRGYDVCPDVTQTFDLDGPRLVSLAASVGMVAAV
PETPTAPPVHARPERLVQKQRAGASLAVLNHVPFPAIIAEFMTAATAAGLTIPVIAAVAV
FTDRVSAAVLQGLPGLELNESVTERVLGAADPVAAGVAAAVAEARALLSIEGVAGVNVSG
LASASGGRLGAEIKAEVGRVIRAEAS
>A0A411ZRS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megamonas rupellensis|TrEMBL
MTRISVELVPRDIEVLKEEVKTIKEKLSDVDFINIPDLLSCDTRSWDGANIAKAYFDDVV
PHLRAMDFDFTKELPIKDKLREYNIKEVLVIEGDPPQSMLYQVYPTISTDIIKKFSEEMP
EITVYAGIDQYRSSMKEEEYRIRRKQLAGAKGFFTQPFFDMRYLEMYADLLDGLDIYWGV
SPVLSERSVSYWRNKNNVIFPKDFEPTLEWNIEFARKVIEFARKHNHNVYLMPIKAKIMP
YLEGVFAK
>A0A6G7VQA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monaibacterium sp. ALG8|TrEMBL
MMRPTLSFEFFPPMSPAANLRLWTSVERLAPLGPKFVSVTYGAGGTTRARTRAAIATIRE
RARLDVAGHLTCVGASRAETLDVARDFAKQGVRRIVALRGDAPKGAEKFEPHPEGFVSAA
ELVSALRDEGFDEISVAAYPEKHPEAQSPDADIENLKRKLDAGATDAITQFCFDTETFFR
FRDAAAKAGITAPIVPGILPVENFAKMKNFAGRCAATVPAWMEAAFGNVQTEEESHLLSV
SIAAEQCSEMMANGVEHLHFYTLNNPDLTFDICTALGIEPVAMQGVVGGTA
>A0A532V1B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division LCP-89 bacterium B3_LCP|TrEMBL
MIITEKKPLTELLENLEGFEKVFLIGCSDCAALAQTGGDKELEALTIKFTQAGKEVVGTL
LSDGPCHNLRAKQELRGVSDEVSQADALVVLACGAGVQAVADLVSQPVMPGLNSLFLGNV
KRYGWFEERCSTCGECLIADTGGICPVTRCAKSLVNGPCGGSQDGMCEVGGDRPCVWAQI
MDRLKEQGRTGKLDKYQPMKDFERSIKPGVVDLRMENQDARSERLAMVIDGREEKYAHSE
FGKRNWQIMLDDVKPEGLTRLQRDLDAGKFVQTAEIVPPKGVAIEKVLQYGKDIRDYVIA
VNVNENPASVMRLNSLSLSHLFAREGIEPIFHITTRERNRLALQSELLGAYVLGVRNVLV
LTGDHQSMGDHKEAKPVYDLDSVQLLRLCTEMMGGKDYNGHDLDGAPDFYLGAVVNPGSD
LLDLQIMKMRKKALAGARYFFTQAIYDLKIFENFMDQVKDMDVKILAGIIPLKSAKMARF
MNKNIPGITVPEKLIGRMEKAQDRTAESISICKEISEGCRDLCNGVHIMPIGWYSIIPQI
FDPVKD
>A0A7C5RFN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium|TrEMBL
MKIIDILREEEYCISFEFFPPKDEELYNEFTKNFDFFNRLSPNFISITYGAGGSTKDKTY
NLVKFAKERYKFPVMPHLTSLTHTPDEIKQILDSYVDIGIENILALRGDVPKWMKDFDVN
SVYFKNALKLIEFIKSNYGDTFCIGVSAYPEGYPEYRNLDKEVDYLKDKFSAGGDFAITQ
MFFDNSYFYNFVDICYKKGIKNEIIPGILPITNFRQVLSFATNVGTEIPKSISERFEKVI
DSPEDSEKLGVEIAVSQIVDLIDNGFKKIHIFTLNRKGITEAITLAIKSKIMLS
>A0A7Y8BNW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas gingeri|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKIPAAPHLSCVGDSKADLRGLLQQYKDAGIQRIVALRGDLPSGMGMASGELLHANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTKSIQAFG
EQVISEMCDRLLEGGAPGLHFYTLNQAQPCLAIWNNLKLPR
>A0A3D3XRA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
MTDILANAKGCEFTFEILPPLKGQKAQEIFDHIDPLMEFKPPFIDVTYHREETVYKRLPN
GLLQEKVVRKRPGTVGICAAL
>A5HUH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MNADAKAQVRDFMAGFTIETTPGAAAKIPDYREHLRPGATVAVTFLPGSDYADTVAVARR
LRAEGFEPAPHIAARSITGEAALRDFLARLRGEAGVTHAVVLAGAVDKALGPYDSSMAVL
ESGLPDEFGITTIGVAGHPEGSPDISDEALAAALQFKNDLAERSGADFYLVTQFVFEAAP
VIAWERAVRAAGNRLPVHVGIPGLATLKTLISHARACGIGPSMRFLTRQTRNVARLVKVS
APDKLVLDLARHGRADAGCGIVKAHIYPLGGLRRSAEWAYALSDGAFTARGDVLTPDTAV
V
>A0A2N9MPR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfopaludibacter sp. SbA3|TrEMBL
MEILPPRGVDASREIEGARRCAEHGIDCINVPDGPRASARMSAQVTCQLIQQEAGIEAVN
HFCCRDRNILGIQSELLGTHKVGVRNLICITGDPPRMGAYPDATAVFDVDAIGLVNIVRN
LNHGLDIGGNPMGSQTALLIGVGANPGALNMDEEIRRFQWKVEAGAEYVVTQPVFDLDLL
EKFLVRVQHVKIPVICGIWPLTSYRNAEFMVNELRVPVPEEFMARMRSVDSAEKARDEGV
AIAREMTARVRQMVQGVQLSAPFGRYQMALDVAEAIGPR
>J1NZ88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae 2070335|TrEMBL
MSRQTPSLSFEVFPPNPAVGNGNIISALQYMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNQQSLG
>S9QM77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litoreibacter arenae DSM 19593|TrEMBL
MTRPNVSFEFFPPKSVEASFRLWDTIQTLAPLDPTFVSVTYGAGGTTRELTHEAVTALHK
ATDLRVAAHLTCVDATREETLAIARDYIKSGVTDIVALRGDAPKGQDFKATENGFASSIE
LIEALKTETDATIRVGAYPDSHPEAGSMEANIAYLKRKFDAGADAAITQFFFEADTFFRF
RDACVKAGIDKPILPGIFPIEDWTRASNFAKRCGTVVPAWLDEAFATAIRDDRHDLLAQS
VVTELCSDLVDGGVDHLHFYTLNRPELTRDICAALGVTPKVALAQVA
>A0A0A2M7P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium suncheonense GH29-5 = DSM 17707|TrEMBL
MKVTQHIEKANGKSLFSFEILPPLKGQNIQCIFDNIEPLMEFKPPFIDVTYHREEYEFKE
LPNGLLEKKIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDMDFLGIDN
VVALRGDAVKSEIYFKPEKEGHSYASELVTQINNLNNGIYLDADLQNTNKTNFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGADYIITQMFFDNKKFFEFVDKCRAAGITVPIIPGLK
PISTKKQLNLIPHRFKVDLPDDLIMEVVKAKDNEAVSQIGIEWCIAQSKELQKAGIPVLH
YYSMGKSENIRQIASQVF
>A0A3A5EJT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas sp. CFBP 7698|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLKGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFEAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQAADALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVAIPIIPGIMPISNFSQLRRFSEQCGAEIPRWIGKKMQSYGDDADAVRAFGAEVV
ATLCQRLIAGGVPALHFYTLNLAKPTTQVLQLLGR
>A0A3C2ARG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryomorphaceae bacterium|TrEMBL
MKITDILANTKGCEFTFEILPPLKGQRAQEIFTNIDPLMEFKPPFIDVTYHREETVYKRL
DNGLLQEKVVRKRPGTVGICAAIMHRYDTETVPHVLCGGFSKEDTENLLIDLNFLGIENV
VALRGDQAKHESYFTPHPEGNSFAIDLVKQIKQLNQGNYLDEDLQNTTATNFCIGVAGYP
EKHFEAPSYNIDIEHLKAKVEAGADYIVTQLFFDNSKYFAFVDKCREAGINVPIIPGLKP
LSTKRQLSILPQIFHVDIPDELAIQAIKCKDNGQVKQLGIEWCIQQSKELKAAGVPVLHY
YSMGTSANIKEIASAVF
>A0A1M5UGU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jatrophihabitans endophyticus|TrEMBL
MELTRRIREGAGEVLLFALTPPRLATATARVQEIADATIARLRGLDLDGLVLYDIDDEVE
RNPQQRPFPFVPTLDPADYLAAHLGDWTTPAVVYRAVGKYAPAELRSWLATQDPSRVLTV
LVGAASSSLRPASTLTEAQAWARELNPELVVGGVAIPERHHRRGDEHVRMLAKQRAGCRF
FVTQVVYDVNAAKNLVSDYFYACAERGTAPAPIVFTFSVCGSLRTLEFLEWLGVDVPRWI
ENDLTHAGDTVLASQHVALAAAVELIEFCRRLGMPFGVNVESVSIRRVEIEASVGLAGQL
QAALAGGVGEDDAAQRAGRTTTDTG
>A0A2W5WUC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter segnis|TrEMBL
MTLPPTRRVIGPVARAGERTSRPRVSFEFFPPKTPQMEESLWQAITRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILDETSLKPAAHLTCVGASRAEVDEVIRDYWDIGVRHIVSLRGD
PPPGEGGIGGVYVPREDGYANATELTKAVRAIGPFEVLVGVYPEKHPESPSLEHDIDVLK
QKVDAGATLGVSQFFFDLDAFLRYVDKVRAAGITIPIVPGIMPVTNFAGLKKMAAACQTT
IPGWLANLFDGLENDAETRRLIACSVATEMCAKLQEQGFEDFHFYTLNRADLVYAICRVL
GLRETAPAPAEVAA
>A0A192LZ33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. N113|TrEMBL
MALKNEGRGRNFGISFEFFPPKSEEMEGQLWDTVAKLQDWDPDFVSVTYGAGGTTKAPTL
SAVTRFLSQTPLATASHLTCVGATKEETHQMIDTFRKVGVKHFVALRGDAPGGVGAPYQP
HPGGYANAAELVAGLKSVGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQF
FFDNDNFERYLERVRAAGISIPIVPGIMPIQNLTQLKRFAGACGAVIPAFLDERFAGFDD
KPEDRAKVAAEVAAEQIEDLVRRGIGDFHLYTMNRAPLVSAVLDNLGYSRRAAKSAGAAA
>A0A4Q2LP55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verminephrobacter sp. Larva24|TrEMBL
MIAASAQGTGFPVSFEFFPPKTPEGAGKLRAARQQLYALHPDFCSVTYGAGGSTQQGSFD
TVRDILAEGMAAAAHFSCMGATGPSVREQLATLKAMGVKRLVALRGDLPSGYGAGGQFQY
ASELVAFIRAETGRDFHIEVAAYPETHPQARSPEADLNAYLRKVQAGADSAITQYFYNSD
AYFRFVEETRRLGADLPVVPGIMPISSSMQLLRFSDACGAEIPRWIRLRLQAFGDDSASI
KAFGLDVVTDLCDRLRSAGVPALHFYTLNQSTATLEICRRLGI
>R6EG35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium CAG:215|TrEMBL
MRSATEQIAGLHPSYISVTYGAGGGTSKNTAKIASYIRDELGVESLAHLTCASSTKAEVQ
TVIENLKALGIENILALRGDIPEGMVFPSEDRYHYAYELVEAIRRSGDFCIGAACYPEGH
VENEHKEDDIKFLKQKVDSGVDFLTTQMFFDNDIHYNFLYRIREAGITVPVLPGIMPITS
AAQMKRSQELSGTVFPRRFLAMLDRFGDHPKAMEQAGIAYATDQIIDLLANGVKNIHIYS
MNKPHIAAKIMENLSEVIQC
>A0A0H2WGJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia mallei (strain ATCC 23344)|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A829IBA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus agalactiae FSL S3-586|TrEMBL
MSKFLEKLKTDILVADGAMGTLLYTYGLDTCHESYNVTHPEKVLAIHQAYIEAGADVIQT
NTYGAQRHRLKNYGLEDQVVSINQAAVNLAHQATLGKETFILGTVGGFRSQRQCDLTLDN
IVEETLEQVEALLATGQLDGLLFETYYDIEEITTVLKIVREMTDLPIITNISLHEAGVTS
NGKPIVEALSQLVMLGADVIGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASQLSLDGE
NSQYQFSQNSEYFGKSAELLVAEGVRLIGGCCGTTPDHIRAVKRSIRGLKPIERKVVTPI
IPVKDFVRRIRRTDTLVDKVKKEVTIIAELDPPKHLDIVQFQKAIRAIDQKGIAAITLAD
NSLSNTRICNLSIASLLKDEISTPFLLHIACRDHNLIGLQSRLLGMELLGFNHILAITGD
PTKLGDFPGATSVYDVTSFKLLSLIKQLNQGLSYSGASLRRPTDFTVAAAFNPNVKNLTR
TVKLIEKKVASGADYFMTQPIFDHSVLKELADLTKTVEQPFFIGIMPITSYNNAVFLHNE
VPGIKLSESFLSALEKVKDDKEACLTLALNESKSLIDEALNYFNGIYLITPFLRYDLTLE
LIDYIQKKQVRKSS
>A0A7Y6KRY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CAI-78|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A1C0B9L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter thereius|TrEMBL
MFEILIQKLQEDKFFTLETTPQHEPSMHNIIEKIKKFKIDSKVDGFTCTDNPLAKLKYSS
LFAALKLQTEFKKPVIATMTMRDRNRIALQSDILGANDFDIRAILALTGDPAHMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDVSGRPFKIEPKQIFPFSVVNSYSKNFGSLEKKMHQKI
QNGAVGVITQPVFDIENVKKLLESFENAKENVEGEKRKSQLILGLFPITKLRTALFLSAQ
VPGIHVPQLWIDELEKAHTISEEEEYKVGMQLSQNLFKEINKIHPKIHLMTSNNKFDVAS
ELLS
>G0VNQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megasphaera elsdenii DSM 20460|TrEMBL
MHTNELFAKKTVFSFEVFPPKKDIPIETVYPTLEELSKLHPDFISVTCGAGGTGGNRTVE
VASRIKALGCETAAHMPCIYLTKEAALQDLKELKEAGIENILALRGDEVPGRERAHDFEH
ASDLVAFIKEQAPEFNVIGACYPEGHTEAKTLAADIRNLKTKVDAGASELISQLFFDNAL
FYRFLERCEIAGINVPIEAGIMPVTNKAQIERMVTMCGATLPIKFQRAIAKYGDTPESMR
DIGIAYAVDQIADLLANGVDGIHVYTMNNPYIAKKIAEAVKTLL
>A0A238UDR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum jejuense|TrEMBL
MKVTEHIKKAKGKTLFSFEIVPPQKGQNIQQLYNNIDPLMEFKPPFIDVTTSREEYIYIE
KENGLLEKKITRMRPGTVGICASLKYKYDVDAIPHVLCGGFTKEETEYVLVDCHYLGIDN
IMALRGDARKDQQYFQASNGGNKFASDLVKQISDLNKGKYLHEIIETPYKSDFCVGVAGY
PEKHLEAPSIESDLKRLKEKVDSGADYVVTQMFFDNQKYFNFVEKAREAGINVPIIPGIK
PIAVKRHLHVLPQVFRLDLPQELVEQIEACKDNKQIREVGIQWAIQQSKELIKAGVPVLH
YYSMGKSDNIMKIAKEVF
>A0A1C3P7V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Frankia californiensis|TrEMBL
MPVTNVAQIERMAKLSGAAFPTDLARRLHAVSDDPAAVRAVGVEVAADLCEKLLAGGAPG
IHFITLNRSTATREVFHSLRG
>A0A553AKM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. GT3R68|TrEMBL
MKVTQHIENAKGKSLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEFEFKE
LPSGLLEKKIVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDIDFLGIQN
VVALRGDAIKSETYFKAEKGGHLYASDLVSQISNLNNGVYLDADLQNSCRTDFCIGVAGY
PEKHIEAPSLDSDIHFLKKKIKHGAEYIITQMFFDNQKYFDFVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSVELPDDLIMEVVRATDAEAVNQIGIEWCINQSKELIKAGIPVLH
YYSMGKSQNIKQIAQSIF
>A0A1M5BBM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptoalloteichus hindustanus|TrEMBL
MVAVVDRVRCGRPVFSVEFLEPRDSEGERQLWRAVRSLEPLDPAFVSVTYGAGGTRRDRT
IRVTGRIAQETTLVPVAHLTAVNHSVAELRNVIGWYAAVGVHNVLALRGDPPGDVHGEWI
RHPQGLAYAEDLVRLVRELGDFCVGVAAFPYGHPRSTDLEADTTYLVRKIRAGAHYAISQ
LFFDVEDFLRLRDRVAAQGIDLDEVPLLPGMMPISTFRGVQKMAHLAGAPVPSTITSRIE
RYADDPKALRAEGVDIATEMGQRLLDEGVNALHFYTLNRSLATSKVVSRLGLVPTRA
>A0A369ZU30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus paraphrohaemolyticus|TrEMBL
MSFATDIDHLNQNIADLNGKINVSFEFFPPKNEKMENLLWDSIARLAPLKPKFVSVTYGA
NSGERDRTHSIVKSIQQETGLIAAPHLTGIDATPDELRQIAKDYWDNGIRNIVALRGDEP
EGYAKKPFYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRAIS
QFFFDIDSYLRFRDRCVNVGIDVEIVPGILPVTNFKQLQKMAKITNVKIPSWMHRMYDGL
DDDPTTRNLVAASIAMDMVRVLSKEGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A0S8ASG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira bacterium SG8_35_4|TrEMBL
MSLKDALDSGKFVVTAEVGPPKGTDIKKILHEAEMLKGKVDALNVTDNQSAVMRISSVSF
CRLLLEMGNEPILQMTCRDRNRIGLQSDLLGASILGIRNVLCMTGDHPNAGDHKEAKPVY
DIESVQLLRVVDSLNNGKDMMGNEMLGSTDYYQGAVVTPEANPLEPQLMKFEKKVDAGAK
FFQTQAIYDIDKYKEFMQYARKFPVKILAGLVLLKSAGMANFMNKFVPGITVPQGLIDEL
KEAGKEKALDAGIDIMARHIKQLKEENICDGVHIMAIGAEDKVPAIMERAGLL
>A0A4R0QLU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chlorobium sp. N1|TrEMBL
MLVKEILNTAEKPVFSFEFFPPKKDADWDTLFKTITALSPLDPSYVSVTYGAGGSTRTRT
HDLVTRIQKETGLSVVSHLTCICSSSPETGEILENYRRHGINNVLALRGDKPAGTATLEE
AIKDFPHAIDLVRFIKTNYPDFGIGVAGFPEGHPETPNRLTEIEHLKAKVDAGADYIVTQ
LFFDNRDFFDFRDRCRLAGITVPIIAGIMPVTTKKGMIRMSELALGARIPAPLLELVMAA
GSDREVASIGIDWATRQVQELVDNHVRGIHFYTLNMADATLRIFRNLHA
>A0A2M7SQK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG_4_10_14_0_8_um_filter_57_5|TrEMBL
DVINVADSPMARMRMSAWAVCDVIQRQVGVETTLHFPTRGRNLLRVQGDLLAAHALGIHN
VFVVMGDPTAIGDYPEAMDNYDLVPSGLIKLIKQGFNLGMDHSGTSIGQPTDFFVGAALN
LNPPEPGSEIKNLHRKARNGADFFLTQPIYRGEEGPAFLEKYAALHGALDRPVLAGILPL
VSLKHANFLHHEVPGVSIPEETRQRMEKAGEDGPRVGVELAVELIQKIKPWAQGIYIMPQ
FNRYDMVAEIIEAVKE
>H1VMU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum higginsianum (strain IMI 349063)|TrEMBL
MHIKSMLDETRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREQEK
WEATDDGFRYAKDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDGDNFVRWVGKVRERGINVPIIPGIMPIATYASFIRRAKHMNCKVPDDWMAAL
EPIKNDDVAVREVGKGLVADMCRKIVAAGIHHLHFYTMNLAQATRMVLEELNWMPTSDRP
VKHALPWKQSLAHGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPRSIKDVANIFVRYLETELDSLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSTHPVHGWGPANGYVYQKAYLELLVHPDVYAEIVSRVEKNP
DMTYYATTKNGSLKYNATHDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGIDW
AHCFEAGTPSRVLIERIMNEWYLINIVNNDFHQKTALFDMLEGLEVKEYADIPAEPQTNG
AVETNGNSVSATPN
>A0A432TSV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thioglobus sp|TrEMBL
MKTSFEFFPPRTDKGKQSLAQVRQELSKIHPEYFSVTFGAGGTTQDATLETVLDIQANDG
ISAAPHLSCIDSKKSKIIELLDQYKAADINRLVALRGDIPSGVRDIGDFHYANELVEFIK
SEYNDHFHIEVAAYPEVHPQAKNIQTDLQHFANKVKAGADAAITQYFYNADAYFRFKDEV
EKMGVDIPITPGIMPITNYTQLLRFSNMCGAEIPKWILERLKLYENDLESLTLFGTEVVS
NLCRTLKDQGVDSFHFYSMNRTEPSLTIAKSLI
>A0A5E6RH55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVQAMGVHIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISTMCEDLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2T4H1K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium culmorum|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDAEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSVEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFNGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLERLDAVKGDDERVKMVGVDIVNELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAVVAVDELAIPALQINGNMRSSSHSRSRQSRRHSSVA
SDPHNYVIVGDRPAVYPEWEATGLEAGGRAEAVNTRANTLAISEGEGALGREATWDDFPN
GRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWDYPKTRQDINDLFVKHIQGELSAIPWSE
EELRAESSTIKPHLLQLNGKGWWTVASQPAVNGLRSSDATFGWGPPNGFVFQKSFVEFFI
PANEWEILKAKLVSSELQDYVCFYASNARGDYVSSDIGGHVDGSTEASPSTNAVTWGVFP
GKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNLIHHDY
VNRDALWEVLSS
>M5W952|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prunus persica|TrEMBL
MKVIEKIQEALLEEKKVLFSFEFFPPKTEDGVENLLERMERMVAHNPAFCDITWGAGGST
ADLTLDIANKMQNIICVESMMHLTCTNMPVDKIDHALQTIKSNGLQNVLALRGDPPHGQD
KFVQIQGGFACALDLVTHIRAKYGDYFGVTVAGYPEAHPDAIGTDGLASPEAYQSDLAYL
KRKVDAGADLIITQLFYDTDVFLKFVHDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPAEVTAALEPIKDNEEAVKSYGIHLGTEMCKKILAHGIRTLHLYTLNMEKSALAILMN
LGLIEETKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDLYPHGRWGDSRN
PSYGALTDYQFMRPRARDKKLVEEWVVPLRSVEDIHEKFKKFCLGKLRSSPWSELDGLQP
ETKIINELLGKINTKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKL
NALVEKCKALPSLTYMAVNKDGRWISNIGQTDVNAVTWGVFPAREIIQPTVVDPASFMVW
KDEAFEIWSRGWACLYPEGDSSRKLLEEVQNSYFLASLVDNDYIQGDVFAVFADF
>A0A249MXL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium xenophagum|TrEMBL
MSLPSIHPNWDLPPKGMTDGYSLEITAKDIDALREAAPAMAPETPVAVTFLPGESLEARI
EAARTVRALGFEPMPHFSARRLESGDDFEAYLAAVVREAGVTRCFIIAGDPPEAAGPYSD
SMSLIRTGAFERAGIKAIGVGGHPEGHPNMTPDQCFDILIAKCAEIEARGMAPLIVTQFS
FDAAPVLSWLEELRGRGIDAPVRVGIPGPAGIKTLMRFAARCGVGASASVLTKYGISITK
LIGTAGPDKLVDALGKGLGSQHGKVRLHFYPFGGLARTVEWINNYTKSR
>A0A2C6DJU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Budvicia aquatica|TrEMBL
MSFFHANQREALNQSLAELSGQINVSFEFFPPSTSEMEQTLWQSIDRLKTLKPKFVSVTY
GANSGERDRTHSIIKGIKDKTGLDAAPHLTCIDASKGQLLEIAQDYWNSGIRHIVALRGD
LPPGGGKPEMYAEDLVHLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPQWMTQMFA
GLEDDAETRKFVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPA
>A0A6A5T754|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Byssothecium circinans|TrEMBL
MHISEKLALSRAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHDFGPTFIDVTWGAGGTLS
HLTCEMVKVAQNVYGLETCMHLTCTDMEKSKLDDALKEAKLAGCSNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIRERYGDYFDIGVAGYSEGCDDNDDVDELIDHLKEKVDAGATF
VVTQMFYDTDVFLDWVGKVRAKGIQVPIIPGIMPIHTHAAFLRRANWTRCTIPKHWTEAL
EPIKNDDAEVRQAGKALVAEMCRKLINAGILHLHFYTMNLAQATRMVLEELELLPDLESP
LQKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDARSPAFGELDA
YGIGLKGTNAQNIKLWGAPESIKDISDLFVRYMTGKLDSLPWSEAPISKEADTLRQDLVN
LNQRGFLTINSQPAVNGAKSSHPVYGWGPRNGYVYQKAYLEILVSPEHIAELITRIERDQ
DLTYYAVNKEGDLKTNSPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYKVGKEW
ANCHASVSPSRYVIEDIMDTWYLVNIVQNDFHIEHGIFPLFDGLCVADMEKPLHQIDVPN
GHATNGEASPNGKKSTLNDLVEAAKAAAGSAADTVTSSISGLKISS
>A0A5C4YIC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAAGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLEKSKDFSYASDLISF
IKKQEYFEIYAACYPEKHNESKNFIEDIHHLKTKVNAGTDKLITQLFYDNEDFYTFKQNC
ALAGIDIPIYAGIMPITNKRQVLKISQLCGAKIPPKFVKILEKYENNALALEDAGIAYAC
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKHLLKEELHA
>X0PJW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus farraginis DSM 18382 = JCM 14108|TrEMBL
MSLTALFNDKTVFSLEVFPPKKDSPKEAILPTLQQLQAINPDFISVTLGAGGSDHYTGTV
SIADLIQNQLNIPAVAHVPGLYQTESQVLNLLDHLSEINVKNILALRGDKIPGKEPVGVF
NHANELVSFVHKNRPDFSIASACYPDCHAEATGFVDDIAHLKEKVDAGADHLISQLFFDN
QSFYDFKEKTEIAGIHVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQDSKLA
MKDAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWEATKSVFEAASQKKAEKAEKA
SNH
>A0A0J6Z057|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8J5GBJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MEQAWTRCLHANAGSASFVIDKSDDAVFIAFSRAQAAASPSGLGRGFFEHVSLYSSTHKL
FALLGRGEEDSGRKPQPVLLQVGALRLFMSLHPMKKKLNVQLFAKVTRRLRLPQKTYMDT
LTFGAPRFFHHLMDPSSKKIYVMKFEVSKVCMETIMHLTCTNMPVEKIDHALNTIKANGI
QNVLALKGDPPHGQDKFVQVAGGFACTLDPVQHIRAKYGDYFGITVAGYPKAHPDMIQGD
EGATLEAYNSDLAYLKRKVGNS
>A0A357LG96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvularcula sp|TrEMBL
MTDLHVSFEFFPPKTEAMQGKLWAAVEKLKPLAPDFVSVTYGAGGSTRERTHDTVARIIK
EAGLPVAAHLTCVAATKAEVDAVLREYWAQGVRHIVALRGDPPGGPGERYIPHPGGYANA
AELAAGARKVGAFEISVGCYPEKHPDSPSHAADIDMLKRKIDAGATRGITQFFYDNDAYF
RYLDRVRAAGVAIPIVPGIMPVTNFAGLRKMADTCGTTIPGRLVKLFQNLDDDPSTRLLI
AATVAAEQCLALAEQGVKHFHFYTLNRDDLAYALCMMLGVRPKPAAKAPAQSAGAAA
>A0A2P5VUA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium barbadense|TrEMBL
MKVIDKIQSLSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGITVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
NIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQFMRPRARDKKLQEEWATPLKSIDDIQEKFKNHCLGKLRSSPWSELDGLQP
ETKIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSLDKL
DVLVKKCNSFSSLTYVAVNKKGNLLSNIGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVW
KDEAFEIWSRSWSALYPDGDPSKNLLEEIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A6B1DH22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRRIPDIYAAKRATGRPVVSVEFFPPKTPAGEDRLFDEVLPALGEAPPDYCSVTYGAGGG
TRGRTLQIVDRMQREHGLTAMAHVTCVSFTRGGMQTFLDEAATLGIENILALRGDPPADQ
PDFRRPEGGFDYASDLIGVIRRTRSDEFAVGCAGFPEGHPDCAEGKHADWGHLKTKVDAG
AEFVLTQLFFDNAYYFEMVDYVTGALGVTVPITPGILPILNTKQIKRFTALCGATLPPPL
LAELDRLGDDDASVTAFGIDYATRQCEALLAAGAPGLHLYGLNRAHSPLAILRNLGLAQQ
PASA
>A0A7S3G8W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Palpitomonas bilix|TrEMBL
MKYFLSKQYSNAKKLHTIIEVFKPATREGENSLMERLNRLATLNPALFSISSQNHQHENN
TLSLTQLVREDVCAEVQVHLQCDEPLEILRANIASAKAFNVRHFLFFVLRQPQALVQEGG
EVSHDSVAIEEALKKMRQLLHLLGEEQSIGVMVPYCDTRDEQIWASVARLACPGIDYVVL
PMIATTQSYSARCNLLTKHGVRCPIVPAIVAAALNARSLESLINSTTAGRDEEWQCIVRQ
LLEIEEQIVLSGRTHRLNVHASEQGRDSSSLSAQKSEERASSTLRSFHSTTIHRIKKQKA
EAIQAFWLSRCVELVEGIQECGSPGRAFTNCFFVEATH
>A0A7C8JEB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orbilia oligospora|TrEMBL
MQEKITDKIKALPKDATYFSLEFFPPKTPAGLQNLHARLDRMAKGLRPLFVNVTWGAGGS
TATKSLELASLCQSHGLTTVLHLTCTNMSKSVLDDALENAKLMGIRNVLALRGDEPRQHE
YLDVTEQVRNGSGENEFVYAIDLVRYIRKQYGEYFAIGVAAYPEGYAETAYPVAQDTARD
LPYLREKTAAGADFIMTQFFYDVEAYISFEKVLRDDESGVFKDIPIIPGLMPVQSYQIFR
RTTKLCSVKVPGTISSRIESVKADDEMVKEHGIQVLTEMIGKIRSSTESDGGLPRGFHFY
TLNLEKAVAFIVERCNLIPEIPTSNEVAVEDEDDEGPGLLTVNGGGAAIPRRSRRTSSII
SDPHNRVIVDTVSSARSELQAEAGEAGVPKILDPGSQEGNLAISEGEGSLGREATWDDFP
NGRWGDARSPAFGEIDGYGVSLHRTPTEALKLWGKPTSTKDISDLFVKNSKGELEAMPWS
EDILNPESFLITEELVKMNAKGWWTVASQPAVNSAKSDHPTFGWGPKNGFVFQKAFVEFF
ILDEEWTELKKKLENEGKEDVSFYAGNKAGDFQTNLASDSSLNAVTWGAFPGKEIITPTI
IEEVSFRAWRDEAFDIWSEWQRIYPLSSATSKLLGELKNKLWLVTIIHHDFVNTDGLWKD
ILGL
>A0A2V5SM82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIMRANSPTFSFEFFPPKTPEAAETLYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
HLVERIQHTTKLDPIPHLTCVCHNEEEIQPILLRYAKSAIGNILALGGDRPAGIAYDKSR
ESFQHAIDLVKFIRRFNESGAHPERRGFGIGVAGFPEGHPATPNRLVEMDYFKAKVDAGA
DYVVTQLFFDNRDFLDFRERCALRQIHVPIIAGIMPITSITGCKRMAELAGGTRFPATLL
RALQHCQNNPEMVRRVGIQYALEQCHDLLDNDVAGIHFYTLNRSDATRIIFDSLGIPRHP
NTPVSTV
>A0A3V7PJX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Javiana|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8C8LR68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
INSGGESSKESSRSSTPVLAADRTERLRDKMRRRTESGDHWFSLEFFPPRTASGAVNLVS
RFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQTKEKI
TGYLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYATDLVKHIRCEFDDYFDICVAGYP
TGHPEADSYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVRDCRAIGITCPILPGIFP
IQGYQSLRQLVKLSKLEVPEEIMRVIEPIKDNDAAIRNYGIEQTVGMCRVLLESGNVPGL
HFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRT
QDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEELTSEQSVYEVFTSY
IKAQPNCAGHKVMCLPWNDEPLAPETNLMMDELDKVNRRGVLTINSQPTINGKPSDDPIV
GWGPPGGYVFQKAYLEFFTSSENVTVLLKVLKKYEPRVNYHIVNVHGQNTTNAHDMQPNA
VTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAELYDDESPSRMIIKYIHDNYFL
VNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPTEQPVEQPAEESPVEDQSPK
>A0A6G1LUU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Orbilia oligospora|TrEMBL
MAKGLRPLFVNVTWGAGGSTATKSLELASLCQSHGLTTVLHLTCTNMSKSVLDDALENAK
LMGIRNVLALRGDEPRQHEYLDVTEQVRNGSGENEFVYAIDLVRYIRKQYGEYFAIGVAA
YPEGYAETAYPVAQDTARDLPYLREKTAAGADFIMTQFFYDVEAYISFEKVLRNDESGVF
KDIPIIPGLMPVQSYQIFRRTTKLCSVKVPGTISSRIESVKADDEMVKEHGIQVLTEMIG
KIRSSTESDGGLPRGFHFYTLNLEKAVAFIVERCNLIPEIPTSSEVAVEDEDDEGPGLLT
VNGGGAAIPRRSRRTSSIISDPHNRVIVDTVSSARSELQAEAGEAGVPKILDPGSQEGNL
AISEGEGSLGREATWDDFPNGRWGDARSPAFGEIDGYGVSLHRTPTEALKLWGKPTSTKD
ISDLFVKNSKGELEAMPWSEDILNPESFLITEELVKMNAKGWWTVASQPAVNSAKSDHPT
FGWGPKNGFVFQKAFVEFFILDEEWTELKKKLENEGKEDVSFYAGNKAGDFQTNLASDSS
LNAVTWGAFPGKEIITPTIIEEVSFRAWRDEAFDIWSEWQRIYPLSSATSKLLGELKNKL
WLVTIIHHDFVNADGLWKDILGL
>A0A2V5VQE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MTARAAKRPVISFEFFPTKTEEGERVLLEKTIPALRQLKPDFCSVTYGAGGSTRDKTLTI
VDRIQRQHGLTAMAHLTCVNATKEEIRAYLTEARSRGINNILALRGDPPGGTGEFRKTEG
GFEFSYQLVEFIRQVGGFSIGVAGFPEGHIACKEGKYVDWPRLKNKIDHGADFVITQLFF
GNRDYFQFRDFLTNLGVSVPLVPGIIPILSTAQIKKFTALCGADLPKPLLNELEKRGDDD
EAAAQFGIEYATRQCEELLREGAPGIHFYTLNKARSTTAILNNLRLR
>A0A6I4ZAD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSFAEAMERGEFPVSLEITPPRTSRPAVLLRRARLLEARTLTVNVIQRPERQSSLEAALE
LKREGLEPIWHLATGGRTRDAIATDVAQAHEAGLGHVLCLRGDHAADTPGTRVTEAIAIV
QEQAPGMAIGAALDQYRTDERSDNLLAAKLQAGARSIWTQPVFDLAPLLRSAGFVKAVRP
DAHVVAMAMPLLTPESLDAISERLRIPAPEALRTRIAAGEKEAWDAFEETLATLARVELV
DAVAIMTYRADPPAGTAERIIAALRRTGIGDTAGAPADR
>A0A7Y2N1U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp|TrEMBL
MEATTSTFSPPSHLIAEIDPPKGTNLDTFLDKALKIRGRVARVRVTDNEHAILRMSPLAP
CRALKEKGVEPSMVINGRDRNRLSFQGDLLGAATMGIDDVVLKEGHDPKEGDQPMARTSG
DLDLETMLICASAMNDGKDLAGEELDGGTNFNIGVYIELSDDVNFNRERAEYFLKLKDFG
VQSVTLGPTYDLNIVEQFQPFAEQTGIKLYSSLMFLKSVTMIRYLNNLPGVPSIPQEFLK
KMMGATDKKNAGMEVAADFLKELAPISDGVVLLSLGLHDKMTEFLDLIER
>A0A6B0X4S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MQQTATLRHLLEETDRFITCVELVTSRGTLADRGGKRVLEMAQALAADPRFDALSITDNP
GGNPMISADALGTPLKEGGQEVIIHLSCKDFNRNGLMGQAWKLANGGFDNILTLSGDYPI
AGYQGQSSGVFDIDSVGLLQLLSDMNEGHFEDASPGRKPRPLKPTRFFLGAVVNNHKRLE
AEVMPQYFKLAKKIRTGARFIINQIGYDARKQDELLKYMALHGLHVPVIANVFVLSGGVA
RFFHAGRIPGVEVTDELLAVAQKQAASPDKGRSFFLEFAAQQCAIAQGLGYRGVYLGGHI
GAEEYGRILELAAQYAADDWRDFARQIRYSRPGEFFYFEEDPDTGLASTQVTQAYLDSKT
SSGRRRAPLTYRINRQLHDRVFEPGKALFRLGASLARKVEGGKLQKPLHTVEHAVKIAAF
DCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTRQGKCEIGDKDCIWARAYDRLKAYGE
EEQMLGDAAVIKDAALQGTSAWANAFLQRDHRGKKND
>A0A2V6I306|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHITDIIQGSSPTFSFEFFPPKTPEAADILYQTIRDLESYMPHFVSVTYGAGGSTRDLTH
DLVERIQHTTKLDPIPHLTCVCHNEQEIEEILLRYAKAAIGNILALGGDRPVGIAYDKSR
DSFQHAIDLVRFIRRFNESGAHPDRRGFGVGIAGFPEGHPATPNRLLEMDYFKAKVDAGA
DYIVTQLFFDNRDFLDFRERCALANIHIPIIAGIMPITSIGGVKRMAELAAGARFPAKLL
RALERCQSAPKMVRRVGIQHALEQCDDLLHNDVAGIHFYTLNRSDATRLIFDSLGIPRHR
SAQASSV
>A0A0B2QJZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Glycine soja|TrEMBL
MKIIEKIHAASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVVHNPSFCDITWGAGGTT
ADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD
KFVQVEGGFACARDLVQHIRAKYGDYFGITVAGYPEAHPDVIESDGLATSEGYQNDLAYL
KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT
KIPADIMAALEPIKDNEEAVKAYGIHLGTEMCKKILAHGINTLHLYTLNMEKSALAILMN
LGLIEETKVSRSLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDQYPHGRWGDSCN
PSYGALSDYQFMRPRARDKKLVEEWAVPLKSIEDIYERFRLYCLGKLRSNPWSELDGLQP
ETKIINELLEKINTKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYVEFFCSKEKL
DALVDKCKDRTSLTYMAVNKDGSWKSNVGQTDVNAVTWGVFPAKEIIQPTIVDPVSFNVW
KDEAFEIWSRGWASLYPEGDASRKLVEEVGGSYFLVSLVDNDYINGDLFTVFADF
>A0A174GZQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides finegoldii|TrEMBL
MKVIDLIHNNKKTAFSFEILPPLKGTGIEKLYQTVDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNSPFSYGVACYP
EKHEEAPNIESDLYWLKKKVEAGAEYAVTQLFYDNKKYFEFVEQAKAAGINVPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELVKEALKCKTDAEAEQVGIEWCVTQCKELMSHGVPSIHF
YSIGAVDSIKKVAKIIY
>A0A8D1WU44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sus scrofa|TrEMBL
MVNEPRGNGGPGPRCEGSSSGSESSKESSRCSTPGLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEVTGYLHKAKRLGLKNILALRGDPVGDQWEAEEGGFSYAADLVKH
IRSEFGDYFDVCVAGYPKGHPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFLK
ACSEMGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATTEVLKRLGLWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GQELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTARETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMLIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPPHNEKEPEQ
>A0A137XR19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella anthropi|TrEMBL
MGFYGLSRRPDIGQTTRVSFEFFPPKSEEMEQRLWDTVTRLAPLQPEFVSVTYGAGGSTR
ERTARTVARILKETDVKPAAHLTCVDATREEVDRVVREFAALGVNRFVALRGDPAAGIGE
KYVPTPGGYQNGAELVSGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVKNFCARSATHIPSWLAERFE
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTEAAL
EVA
>A0A1H9NTZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopseudomonas bauzanensis|TrEMBL
MTTSKEIPVSFEFFPTKTEAGHEKLIAAAHVLADQQPEFFSVTYGAGGSTRDRTINTVLQ
LDQQVKVPTAPHLSCVGDSKADLRQLLTEYREAGIRRIVALRGDLPSGMGRASGELRYAN
ELVEFIREETGDHFIIEVAAYPEAHPQARNFEADLENFVRKAKAGADSAITQYFFNADCY
FHFVDRVRKAGVDLPIVPGIMPITNYTSLSRFSDACGAEIPRWIRKQLESYGDDSASIAA
FGTEVISDMCQRLLDGGAPSLHFYTLNQAQPSLAILDNL
>A0A6J0XQZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odocoileus virginianus texanus|TrEMBL
MVNEPRGNGGPGPRWEGSSSGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKH
IRNEFGDYFDVCVAGYPKGHPEAESFEADLKHLKEKVAAGADFIITQLFFEADTFFHFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GAELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQDERETEAP
>A0A3V3U708|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Havana|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A288TT97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella variicola|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A229I5M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella copri|TrEMBL
MNIAEFLHQKGDKRGFSFEVLPPLKGNGTAALFRTIDSLKDFDPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHVICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHSNATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGADYAITQLFYDNEKFYAFVEKARQMGITIPIVPALK
PFAKLSQLTMVPKTFHCDIPEALAQEVLKCKSDEDAKALGIEWTTAQVKDLFDHGYNHIH
FFTVSAVDSVKQIAKILF
>A0A3S3PUY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dinothrombium tinctorium|TrEMBL
MVRGNVRSNSSSSMSSSADVDSGSEDIILSASENNHNCSSKPSSYVPLIEKINQRIKSND
PFFSLEFFPPRTKEGGVNLLSRFDRMREGGPLFCDITWHPAGNPGSDSPTSSITIAGVAL
NYCALETMLHITCVNMGPDELKKHLNRAKELGIRNILALRGDLPENEEMKELYFHYARDM
VRFIREHYGNYFTICVAGYPTKHPEAASYEEDLQHLKEKVDAGADFIITQLFFESQDYIR
YVNDCRSIGIKVPIIAGIMPIQSHDSLRHIVRLSRLEVPKYILEAIKPIASNDEAIRKYG
IELATKMCREILASGTTPGLHFYTLNREVATVQILKNLGLWKKNPQKPFPWLTVPNYKRC
TEEVRPIFWANRTKSYVYRTSSWDEFPNGRWGDSSSPAFGELKDYYLFIGKSKSPLEELR
RMWGKELSSEKDIWDVFYNYVSGSINK
>A0A5F0YF09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium damsela subsp. piscicida|TrEMBL
MQPITNYQALSLQDSELRVRYNDVTRGVYFIGTTPPKTSTELSDVDGIADKLVDRIKDLA
FDGLIVYDIQDEGSRISKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSEPEVFN
QWLNEAWDQYQVRDIVLVGSPSTQNQVSLPLHEAYKTIADNEHPFFTGGIMIAERHAKKG
NEHQRLIEKYQQGCNFFISQAIYDTQATIDLLTRYAIECQEKGLKPQRIILTFSPCGSAK
TLEFIEWLGVSVPEATSLRILNADNPLHESIKMCCNSLNQILEAVVEYDLPLGLNIESLT
NRKEEIEGSILLYKLLRSTMDMYLAQHEFRKQQGLKKPF
>A0A6V7BWN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas hortorum pv. carotae|TrEMBL
MSPDTPSLASTLTDAYSLEVGANDMPALTAAAPRILRGSTIAIPYLPSQNDDARLAAAQR
VRTLGFAPMPHLSARRIASLDALHAFVGRAVDEAGVERCLVIAGDAASAIGPFSDSVSLI
DTGVFERSGITTIGLAGHPEGHPSMPATDQWDVLERKCRSIAERGMAPLIVTQFAFDADI
VLTWLEALRARGIAHPVRVGVPGPAGVAVLARYAARCGVGACASMLSKYGISIGKLFGSA
GPDRFVDRLATGLTDAHGDVSLHFFPFGGIAESVAWVEQYRSRSAAHILSTSASRRSQ
>A0A0W7VP03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma gamsii|TrEMBL
MHIKSLVADTEKTKAPSFSFEYFPPKTAQGVQNLYDRMDRMNNFGPKFIDITWGAGGGIA
ELTCEMVVQAQAVYGLETCMHLTCTDMGIDKVNDALQKAYKAGCTNILALRGDPPRDQTT
WTASDGNFRYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEDSLLDHLKEKVDMGAGF
IVTQMFYDADNFLRWVGRVRERGITVPILPGIMPIATYASFLRRAKHMQCRVPPEWMTLL
EPVKNDDVAVREIGKTLVAELCRKLLAGGIHHLHFYTMNLAQATRMVLDELDWTPSAERP
LKQALPWKQSKGFGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTCVQDIADTFVQYLEKKIETLPWSESALAAEADPIKDDLVA
LNKRGILTINSQPAVDGAKSNHPVHGWGPSNGYVYQKAYLELLVPPYLLDEMISRLDDFP
NLTYYAVTKNGELRSNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFDANTPSRALIEGIMNEWYLVNIVNNDFRENNTIFSFLEGLQVKDASAPANGTA
>A0A1W6M7D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio vulnificus|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSTPQMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKAQTGLVAAPHLTCIDASREELINIANDYWANGIKNIVALRGD
IPPGGGAPDMYASDLVTLLKSLHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMAKQFE
GLDDDPVTRQLVGASQAIDMVRILSREGVKDFHFYTLNRAEMTYALCHTLGVRPKKA
>A0A2M9YN47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira adleri|TrEMBL
MKKISEIYGSKKEPVYSFEFLPPKTPEGDVKLMETVKELSQVNPDFVTVTYGAGGSTRDK
TVQIVTEISKNYSFPTASHFTCVGADRDQIREILKGIRSKGIVNLMALRGDPPRGEGEFK
KTPGGFENATELISFIRSEKLDFCIGGGCYPEKHPNAKSLEEDVRHLKLKVDAGTDFLVS
QLFFMNSTFENFLNLVRKVGIRVPVIPGIMPITSFSQIERFRTLAGCEFPSSLIEDLQEV
EHRPEEFYRRSLNFTVKQCRELLEMGVPGIHLYTLNQTHASYDIVRELKG
>A0A8F9QJG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas citri pv. citri|TrEMBL
MPADMPSGASTITDTYSLEVSVKDIGALTNAAPRILPGSDMFIPYLPGQTEAARLAAAQR
VRRLGFEPVPHLSARRIGSLEELQAVIARLVGEADVTRCLVIAGDPSTPKGPFADSVSLI
ETGVFERSGIRTIGVAGHPEGHPIMRTTEQWDVLERKCRSIQERGMAPLIVTQFGFDADI
VMTWLEALRARGMTHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGNA
GPDRFVDRLVSRLTEAHGDVRLHFFPFGGIAQSVEWVAHYRSCEASQDRVSSVAAD
>A0A7J6MRC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Perkinsus olseni|TrEMBL
MARLIDKIQDRWDHDRDNGESTRVPFFSFEYFPPMTDMGVQNLYERLDRMAELGPMWIDV
TWGAGGSTSGKTFEICRNALTYHGLDVMMHLTCTDQPVKEIDEVLEKCKEVGIRNILALR
GDAPMHSSEWKACQGGFSHAVDLVRHIRGKYGDYFCIAVAGYPEGHLEAESMEEDLAHLK
EKVDAGADLIITQLFYDTEVFFNFVAAVRALGIQVPIFPGIMPIQSYSGFKKMTEFCKTK
VPRAIADQLEQVKGDDQKVKDLGVEICVAMCSQIMSYGADHCHSSGGLHFYTLNLESSVS
RIIERLMMVDSHVATRALPWRPSKASSRQEENVRPIFWSNRQKSFIQRTSCWDEFPNGRL
GNQASAAYGDFELNFRSYSKETQDKVAADRRRMWGDHVPNGDHVRRVFTAFIKGEVKRLP
WCTESPTEETLFIQKQLIRLNQCNMLTINSQPRVNGALSTDPYVGWGPGGGFVYQKAYVE
FFCPESQLEQLIRGIEGEKYESISYMAVTADGSKVKSNIPPQGQVNAVTWGVFPNSEIIQ
PTVVDVTSFMAWKDEAFALWNEWMDVYPEDDHQSRQVLSFIRDHYFLCTVVDNDFVAGDL
FSKLTKICTPIPWETLRIENPSESDGHEVPETSLAVIAEVYSPRPKPTDLSPRHETKNDI
TAFAPL
>A0A0G3M2X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium gallinarum|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
VMALRGDAMKGHQYFEPTQGGHASAMELVNQINDLGRGKYLHNEEQVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVQKAREMGITVPIIPGI
KPIATKRHLKILPQVFKIDLPEELINEVENAKNNEAVKQIGIEWAITQCKELLNFGVPVL
HFYSMGKSDNIKKIAGELF
>A0A447QKY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia rubidaea|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSSLKPKFLSVTY
GANSGERDRTHGVIKGIKDRTGLEAAPHLTCIDASREQLSEIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPSWMTSMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A8J7YY02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Altiarchaeum hamiconexum|TrEMBL
MYKITDIFKRKKKTFSFEFFPPKTEEGMKHLFETCDELKKYPDFFSVTYNPDGSSRERTL
FVVNEIQKKFKIPVMHHLTCINYNERTL
>A0A2W1DIE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenophora tritici-repentis|TrEMBL
MEKITDKINSLPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCIGVAAYPEGHSDQSHPEHQDPLTDL
PYLVEKTKAGADFIMTQLFYDVQAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHARLPAEMLARLDAVKSDDELVKQMGVQIMDEMVEHIKARPETCRRGFHFYTLNL
EKAVSHVVEDTHLIPTTIMDDEEIIVETTPAINLEPPPNGLMARRRRSSAVNSGPFNRVI
ISHGSGAKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGYPVEKKDISTLFRRHIEGDLEAIPWSEQGLSP
ETSTISAQLLALNAKGWWTVASQPAVNGVKSTDPIFGWGPKNGYVFQKPFVEFFIPAAEF
QAFKPKLQAHDQVTWFAGNAAGAFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIWKEWQRIYPPRSGSSVLLGELSKDVWLVNVIWGDFVNGEGLWEFLRQ
>A0A7H8N4Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces buecherae|TrEMBL
MALGTASTRTDHARTVRELLASGEQSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSLTELRNVIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVSYAAELVELIKESGDFCVGVAAFPEMHPRSQDWETDIRHFIN
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCPTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELASRILAVKDDPAAVRSIGIDYATELCARLMAEEIPGLHFITLNHSTATLEIYENLG
LHQRP
>A0A0F3HYH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gordonii|TrEMBL
MVRHHTPSLSFEVFPPNPAVGNEKIIQALREMQDIAPHYISVTASNNKFNIEETTVRLAD
FIYNDLKIPTIAHLPAVYLTKEMVSDTLQALDKVGVHKILALRGDIFPDVAPKDDFKYAT
DLIEYIKEEAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDIPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRA
AGLAYAVDQIVDLVTQDVAGVHLYTMNNAATAHHIYQATHTFFS
>A0A1C2JLX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus thiooxidans|TrEMBL
MAHSVEFFPPKNAAGEERLRETIAALLPLGPEYASVTFGAGGSTRERTFATVDMIRKDYA
LEAVPHLSCIGSTESGIQEILEDYRTQGIQRIVALRGDLPEGMSNPGHFEYAADLVAFIR
QFGGFKIYVAGYPEVHPKAVSAEEDLQHLVEKVQAGADAVITQYFYNPDAYLQLRDDLQR
RGVEVPIVVGVMPITNFEQISRFSAMCGAELPQYLRRRMEAYGEDLQSQYQFGIELLSRQ
CETLLSQGAPSLHFYTLNQSEATTAIWQNLGL
>A0A0U0MDK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSCQTPSLSFEVFPPNPAVGNDNIILALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A263VQE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter asburiae|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A2E5RHW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNMTEEYLKLRDVLGSGEFAITAEIPAPVSASSTEMEEKIKILKGSVHAINVTDNPGATA
HMSSFAGSAIVRNQGIDPILQITCRDRNRLAIQSDLMGASALGIDNVLTLAGDPVKNGDQ
KDAKPVFDINSKTMLSIMDVMNNDGVTMSGKELQTKSSFFPGGAAIVHEPKDNWDPKALS
EKASFGAKFIQTQFCYDAELVKRYMQRIVDAGLSEKMYFIIGIGPLRSEKSAKWMKDKLF
GTVMPESVIKRMEESNDQIQEGADICAELIESFKEIEGVHGAHLMAPRNLSAIPRTVERS
GIVI
>A0A3S7GV11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus hominis|TrEMBL
MSRLLNHLKNNVLVADGAMGTILYSEGLDTCPEAYNLTHPNKVERIHRSYIEAGADVIQT
NTYGANFEKLKVFGLEHKVKEIHKAAVQIAKRAANKETFILGTVGGFRGIKQEDLSLSTI
QYHTDNQIDTLIEEGVDGLLFETYYDLDELTSVITATRQKYDIPIIAQLTASNTNYLVDG
TEINEALKHLIECGANVVGLNCHHGPHHMQRSFSHIELPEHAYLSCYPNASLLDIENSEF
KYSNNAKYFGDVAQELINEGVRLIGGCCGTTPEHISYIKESVKHLKPIKTKKVIPIHRTI
NTNAKRTLKQNLTSKVKQRPTVIVELDTPKHLDTELFFENIGKLDEANIDAVTLADNSLA
TVRVSNIAAASLIKQRYEIEPLVHITCRDRNLIGLQSHLLGLSLIGVSEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNQGINVDGDALKKHTNFNIAGAFDPNVRKLDGAVKR
LEKKVAAGMSYFITQPVYSKEKIKEVYEATKHLDTPLFIGIMPIASYNNALFLHNEVPGI
KMSEDVLNQFKAVKDDKEKTKELSLRLSKELIDTVHEYFNGLYLITPFQRIDYSLELAAY
SKAITQNKEAIS
>A0A1I5YGM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis rubida|TrEMBL
MTSVIERLRGDGPAFSVEFFPPRDEADEAVLWKAIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLCPMAHLTAVDHSVSELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPEGLTYAEELVELVRSLGDFCVGVSAFPYGHPRSADLESDTKHLVRKFRAGADFAIAQ
LFFEAEDFLRLRDRVAAAGCDALVLPGIMPLTTLRTLHTTIKLSGAPASQRLLDRLEPFS
GDPRAFRAAGIDWVTELCEKLIAEGVPDLHFYTFNRSKATREVVTRLGLVPARA
>A0A447KP39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia odorifera|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLDAAPHLTCIDASPAQLRAIASDYWNSGIRHIVALRGD
LPPGSGKPEMYATDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVAASIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPIAAA
>A0A0A0SVR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio coralliilyticus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLKPKFVSVTY
GANSGERDRTHSIIKEIKAETGLVAAPHLTCIDASREELARIADDYWANGIQSIVALRGD
IPPGGGKPEMYASDLVKLLKERHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPSWMAKQFE
GLDDDPTTRQLVGASQAIDMIRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQV
>A0A6W4FLF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria monocytogenes|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVIANVSMHEPGIL
QNGKKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDNAYLAVYPNASLPEMQE
GKVIYQSDTDYFEHYGEIFRQEGARIIGGCCGTTPDHIRALRKGLETTKPILEKEVRPIL
ELVPEEVDDAEQGERLLDKVKEGLTILVELDPPRTFDTTKFFEGAKALDEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKAKIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICEHFQGIYIITPFLRYDLSI
ELAKYAQNKQQVQIGSK
>A0A6I2WWW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MARIADLLARGRTFSFEFFPPKTDYAQLTLGRTIAELESLSPGFVSVTYGAGGGTRARTH
AVVEWVRKETHITPMAHLTCTAHSRAEISEILANYTDAGVENILALGGDPPAAGAEPGPS
DYSYALDLVEHIASAGGFSIGVAAHPEMHPRSADRASDRRYLAEKLKRADFAITQFFFEA
DHYFRMVDELASLGVDKPIVPGIMPVTNKNQVKRMAELSGSVFPAWLAERIGDSGDEAEV
ARIGVEVATELCATLLEGGAPGLHFFTMNRSNATREIYGRLGLPTF
>A0A0T9LVT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia kristensenii|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLREIATDYWNSGIRHIVALRGD
LPPNSGKPEMYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTRIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A6L6E4C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAINFSGNGHCSPHHSNHLGAILSAIVEALNRRTNGGKPTLSFEFFPPKDDAGFDTLNES
FEQLQRLSPDFVSVTYGAGGSNRERSIAVVESFSSRVATIGHLTCVGATKQSTLAVIRQF
EQAGVAGILAIRGDNPADNPDALSQGELKRAVDLVSLAQESSSLPVGVAAFPEKHPESVD
IAADVRVLKIKQDAGAKFAVTQLFFAASHYVELVDAAREAGVTMPILPGLMPIANAKNVL
RMAQLSGASVPSDLHDRLISATDEDAAREIGMAYTVQLGRELLAAGAPGLHIFALNQSKA
ATRVAKEVGLA
>A0A374NYH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hungatella hathewayi|TrEMBL
MKTTDIFAKKPVLSFEVFPPKRTNPVETIYETLDSLRKLNPDFISVTYGAGGSENCKATT
EIASRIKNEYGIESVAHLPCIGLKRDDVISLLGGFKRAGIDNILALRGDIPEGGRPDGDF
GHASDLISFIKENDEFKEFNVLAACYPEGHTESENILTDIRSLKTKVDAGADHLITQLFF
DNDCFYRFRERASLAGIHVPVEAGIMPVTNKKQIERMVSLCGVSLPSKFTAIMERYEHNP
EAMRDAGIAYAVDQIVDLIARGVDGIHLYTMNNPYVAAKIHEAVYRLLAA
>A0A6I3HTI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSQLREKLENTQDLVFTAEFPSIDGGGMASVEKNVARLAPWFDAVNATDNPAAHAHASNT
TTAIAMKMHGLEPIMQIVCRDKNRIAIQADMMGASLHGITNLSLLTGDDVTAGDEPEARR
VFDIDSAQAINIARAMATGTYLSGRAIKPAPDFYIGAVENSAAPPFDYRIQRALKKHRAG
ARFLQLQICYHPDRLEAFCKGVAEVAPDLKLIPTIVIVKGAKPLGFMHDKVPGIDVPSQT
LARVQNASDQSEEVYALTLELAQHALSLPGVRGLHITDFRHDDSLARFMSDLGRTPRN
>A0A1V9VAY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter cryaerophilus|TrEMBL
MFETLISKLQEDKYLTLETTPQHEPSMHNIVEKIKKFKIDSKVDGFTCTDNPLAKLKYNS
LFAALKLQQEFKKPVIATMTMRDRNKIALQSDLLGANDFDIRAILALTGDPANMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFAVVNAYAKNFGSLEKKMHLKI
QNGAVGVITQPVFDIENVKKLLENFENAKENVEGDKRKAQLIFGVFPITKLRTALFLSAQ
VPGIHVPQFWIDELEKAHNISEEEEYKVGMQLSKNLFDEINRIHPKIHLMTANNKFEVAS
EILA
>A0A0S7E529|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myroides odoratimimus|TrEMBL
MKVTEHIQKANGKTQFSFEILPPLKGQNIQGIFDSIEPLMEFDPPFIDVTYHREEYEYKE
AGNGLWEKRTVRKRPGTVGICSAIQNRFKLDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VVALRGDAVKNETYFKPEPKGNKYASDLVTQISELNQGIYLDPELENTSKTDFCVGVAGY
PEKHMEAPNFDTDLKYLKQKIDNGAEYIVTQMFFDNSKFFAFVDKCRSIGIDVPIIPGLK
PLATLSQLNLLPQRFKVDLPDDLVAEVLKAKDNAAIREIGIEWCAQQSRELIEAGTPIVH
YYSMGKSDNIKNIIKLATV
>A0A484P9R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|plant metagenome|TrEMBL
MEVSAKDIPALTAVAPRLPPASTISIPYLAGEGNAARLAAARAVRELGFEPMPHISARRV
ASLAELQAFVARAAAEAGVERCFVIAGDPSTPKGPFPDSFSLIDTGVFERAGIKALGVGG
HPEGHPVMSVADRWEVLERKCRGIEGRGMAPSIVTQFVFDADVVLTWLEALRARGIAHPV
RVGVPGPAGVAVLARYAAMCGVGACASMLAKYGISIGKLLGTAGPDRFVDRLAAGLTPAH
GTVSLHFFPFGGIAQSVGWIEQYRATRKQNTR
>A0A0K1RFI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium riegelii|TrEMBL
MRGTIASTRLSASAPLDTAEEALGTGPETGPGADQGVSRRSRTALSFELIPPRNTADTEK
LDELIGGLAAYHPDYVSVTSSMRSDWLEGTSALIARIASTTDLRPIAHLACTAGTKVELE
GWIRQLIDAGVRGFLALRGDLQPGQKALPEGYLPYATDLLNLINEVQEEEAFRLAAGKLA
LSVACYPSGHAESKNFDHDLDVLLAKQRLGADFAITQLFFDAADYLEFVEVARMAGVRIP
LIPGIMPITSLARAKRMGELSGLEVPRGVEKQLSSAATGEEEYELGMELSADLARTILNA
GTGGLHIYTHNNLAVTRDLLQRIGIEHKD
>A0A350Z4U3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MSWLKQVLQSGHFAVTAEVGPPKGSDPQVIRKKCNLLKGFVDAVNITDNQTAIVRMSSFA
SCLIAQEQGIEPVMQMVTRDRNRIALQSDFLGACALGIPNLLCLTGDHQSMGNHPQSKNV
YDIDSIQLLQIFKNMRDQKVFQNGEEVKGEMNVFLGAGESPYADPLEFRALRLAKKIAAG
AEFIQTQAIFDVDIFTQWMEEVCRLGLHKKSFILAGVIPVKSAKALRYMKNEVPGVVIPD
SLIERMEAAVDQKAEGVEVCIETIQKVAQIEGVSGVHIMAIAWESIVPEIVQRSGLLPRP
AKGEITSS
>A0A178PIV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mammaliicoccus lentus|TrEMBL
MKMKEALKNRILIADGAMGTILYSEGLDTCPESYNLTHPKKIEKIHRSYIEAGADVIQTN
TYGANFEKLQIYNLEHRVKDIHKEAVRIAKRASNEDTFILGTVGGFRNIRKSDLSIESIQ
YHTEIQIETLVNEGVDGILFETYYDLEELLAVLKDTRAKYDLPIIAQLTASNTNFLRNST
PIPDALQSLLDAGADIVGLNCHHGPYHMIQTYKHIDIPKDAYLSCYPNASLLDLEENELK
YSNNAEYFSKSAKELVNQGVRLIGGCCGTTPEHIKKIKEVVKYLKPVHHKNVIPIETKKY
QKQDKQEPSITELVSQKPTVIVELDTPKHLDTDKFFKGVKALEDAEVEAITLADNSLASV
RISNIAAASIIKQNYKIRPLVHLACRDRNLIGLQSHLMGLSLLGINDILAITGDPSKVGN
FPGATSVFDVNSNGLAEIIQQFNQGINADGASLRRNSNFSVAGAFNPNVRRLEPAVKRLE
KKLDSGIEYFITQPVYEPEKIKEIYEATKHLDAPIFIGVMPITNYNNALFLHNEVPGIKL
SEGVLNAFEKVKHDKEATRALSISLSKELIDTIHQYFNGLYLVTPFLKYDITVELAQYSK
SITGTQSKEAIL
>A0A355FEB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium|TrEMBL
MKVIDLIQETSKATFSFELLPPLKGNSIRQVFAVIDRLKEFDPKYINITTHHSESMYKED
AEGVYRKISVRKRPGSVAIAAAIQNKYGIKAIPHIISQGFSKEETEYALIDLSFLGVTDL
LLLRGDTKNLDALQRNLDSHPHASGLQEQVNDFNRGVSFDGSSLTPPEIPFSYGMACYPE
KHEESPNMESELFYTKMKVQNGADYLVTQMFFDNRKYFEFVDRCRAEGITVPIVPGIKPI
HLKNQLTVLPRIFRTDLPEELAKALRTCQSDDEAKQVGVEWCTAQCKELIAGGVPGIHFY
SLMASESVYKVAKEIY
>A0A5F1HU75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia sp. E1130|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1B8J7I1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. CLO-3|TrEMBL
MEAKILGIDLESTIANLHTSAPFLSLEITPPLSGKIEVDSIRELKNLDYINAFVCTDSPL
ARFKPSSILSSLKLQNFLQKPLICTLSMRDRNSIALCGDILAANELGVRAFLSLTGDSIK
LGDCIESKGVFEDNSLKLARIIDTLNSGYGINHKPLSERVQKIYNFHVINSYANNMESLK
TKLAKKLSNSDVEGFFTQPVYDEKSGEFLLNSLERLNSEYGRKSVLIFGFYPILSYKTAL
FLRDKLPGVFVPESLIKSLESASKISKQEEEKVGFKQSAILLQKLQKLNNKIHFMNPNKF
LLFKEYFKGA
>A0A076INA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei|TrEMBL
MGIAELINKEKKTAFSFEVLPPLKGTGIEKLYATIDTLREFDPLYVNITTHRSEYVYREL
GGGLYERNRYRRRPGTVAVAAAIHNKYDITVVPHILCSGFSREDTEYILLDLQFLGITNL
LVLRGDKAKDESSFVPEKNGYAHALELEEQINAFNEGKFIDGTPIQAPLTPFRYGVAGYP
EKHEESPNIEQDLYWLKKKVEAGADYVVTQMFYDNQKYVAFVERARKEGINVPIVPGIKP
FSKLSQLSVIPKTFNVDLPQELVVEAIKCKDDKEARALGIEWCVNQCRELIAYGVPGIHF
YTVGAVENVKEVAAAVY
>A0A1H3PH62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Delftia lacustris|TrEMBL
MSFPISFEFFPTKTPEGATKHVQVRKNLYARKPQFCSVTYGAGGSTQTGTFAMVRDIQNE
GVSAASHFSCVGATHDKVRAELQELKAMGVRRIVALRGDLPSGYGLGGEFQYASDLVEFI
RREFGDWFHIEVAAYPEVHPQAKSPQSDLDAFAAKVRAGADSAITQYFYNADAYCRFVDA
ARGMGLDAPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIRAFGLDVV
SRLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A3B4H1G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pundamilia nyererei|TrEMBL
MVNQVERGDGTCQCKSDSSGASNSGGDSSKESSRCSTPVLDAYRSDRLRDKMRRRMESGD
RWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAV
NYCGLESILHLTCCNQSKEKITGYLAKAKHLGLKNIMALRGDPIGEDWEEEEDGFNYAID
LVKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKEKVDAGADFVITQLFFRPDTFL
KFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITQVIEPIKDNDAAIRNY
GIQQAVEMCRVLLDSGKVPGVHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKR
KVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDAL
LQMWGEELQNEESVFEVFTCYITAQPNRCGHKVMCLPWNDEPLAPETNLLKDELEKVNRR
GVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVN
YHIVNVNGRNLTNAPEMQPNAVTWGIFAGREIVQPTVVDPVSFMYWKDEAFALWIEQWGK
LYEDESPSRMIIKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLDAPPELHSEETV
>A0A0C9LJ76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter tropicalis|TrEMBL
MSLSRLSVELIPRSTEALLEDVASVKALFPAADTLNVPDLMRFPLRSWDAAALIRPHFAR
VVPHIRAIDIAPDAPLPGADQPGLEEVLVVHGDPPADLSHRTYPNSTESIIRRYKKEAPH
LRIYAAFDPYRRAPWQELEDVARKKEAGAEGFFTQPVFDLKLFDLCREWLRDETVFWGLS
PVIGPRSRSYWETTNHVVFPKDFEPTLEANIHFAQTVLRHLSQEKGRAYLMPLRVKLDQY
LPPLLEALA
>A0A383Z4F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balaenoptera acutorostrata scammoni|TrEMBL
MVNEPRGHGGPSPRWEGSSSGSESSKDSSRCSTPVLDPERHERLREKMKRRMESGDKWFS
LEFFPPRTAEGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAVDLVKH
IRSEFGDYFDVCVAGYPKGHPDSESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVK
ACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
ALSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFEVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPSINGKPSSDPVVGWGPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGDNITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLNRPPQNKSETEAP
>A0A401APR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella senftenberg|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6B0XM89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Holophagales bacterium|TrEMBL
MRSAIAEGRPFYSFEYFPPKTEAGIENLYARIERMGRLEPAFVDVTWGAGGSTAELTFEL
ANTIENVLGLETMMHLTCTNMPRRRIAAVLDDCRARGIGNILALRGDPPRGRGAWSPIAD
GFSHASDLVRFIREEHGDHFGICVGGYPEGHPEAPSRERDLDHLAAKVETGADFVITQMF
YEPELYFRFLEECRERGIDCPIVPGLAPINGYQSFQRITGFGASAPPEIVSEIEARRYHD
ASVREYGQDLLTGICRRLLDGGAPGLHFYTLNLERSVQVILDRLGIVPERTERVLPWRSA
TAVQRPREDVRPIFWANRPKSYLARTRDWDEFPNGRWGDAGSPAFGDLGDHHLAFRPIKA
DMARERWGRELPSIDQVREVFAGFCRGDVDGIPWYDWPLDLESEPLRNALVRLNLAGLLT
INSQPRVNGAPSDDPAVGWGGTGGRVYQKAYLEFFVAPEQVPPLLAALEANESLTYHAID
RSGTAYSNCDTVNAVTWGVFPGEEIRQPTIVDPRSFEVWKDEAFDLWLSSWAAVYEEGSE
SRRLLQRIHDTYFLVNVVDNDYVDGDLLGYLLEAIQADEPPSMTIVAPVT
>A0A412JNI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides xylanisolvens|TrEMBL
MKVIDLIHSNKKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLNITEL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVSSTPFSYGVACYP
EKHEEAPNIETDLYWLKKKVENGAEYAVTQLFYDNRKYFEFVEQAKAADINIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEDLVKEALKCKNDAEAEQVGIEWCVAQCKELMAHGVPSIHF
YSIGAVDSIKEVAKIIY
>A0A535M1B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIAHLLNRGRPTVSFEFMAPRDEDEVLILERTVAALAGHAPDWVSVTYRVRTGEKTLEL
VTRIKRQYHIESMAHLTCANTRDETRRILNWMEREGIANVLALRGDPPGPAQPFQPVDPE
LAHGSDLVAFVRGNGYRLGIGAACSAEKHPESPDREHEFRYMQLKVEAGADFLITQLFFD
NRFYFDLIARARAAGIKVPIVPGLMPIPSRRSLAFVTQMSGATVPDQLQQAIDVAPDDEA
IRKLGVEHCIRQCAELLEAGVPGLHFYTFNRARAASEILGALRGQQLLAS
>A0A7Y5NLB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dermatophilaceae bacterium|TrEMBL
MAHGTASSMARAERFTRSIPAMIEADTPTFSFEFFPPKDDAAEAQLWDAIRRLEKVSPSF
VSITYGAGGSTRDRTVRLTQRVLEETSLTPMAHLTCVGHSVTELRSIVGAYAAAGVRNIL
ALRGDPQGGLGQPWVAHPEGLDHADELVRLVKGLGDFTVGVAAFPDGHPESHSVEDDART
LIRKEQAGAQFAITQMVFDVDNYVRLRDELARRGSQMPVVPAIMPITNARQVVRMAQLAG
QPMPAAVTDRLDRHGDDAVAVRAEGMAIATESSQRLLDEGAPGIHFITMNRSSATLEVFG
NL
>A0A511DTG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus kefiri|TrEMBL
MSLTELFKTKTVFSLEVFPPKKSSPTEAILPTLKRLQSINPDFISVTLGAGGTAHCDGTV
EIANLIQNKLDIPAVAHVPGLYQTQEQVLALLDRLDSINVKNILALRGDKIPGKEPVGVF
NHANELVKFVHENRPDFSIASACYPNCHTEAPDFVDDITHLKEKVDAGADHLISQLFFDN
QAFYDFKEKTEIAGIHVPIEAGIMPCTNKNQIERITQISGVPIPKKFAAIMDRYQNSKEA
MLDAGIAFAVDQIIDLVSQGVDGIHLYTMNKSKIAKRIWDETQSVFEASNLSKQTENA
>A0A6G2KRA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MRNDLASLSRWEEPQPAGPNPDVQELIRNSAFEIIPLNSASEAIAALPPQSRVSITASAA
KGQAATLELAEELVNRGHHAIPHFSARLIRDRGQVKDLAEWAKYVGVTTAFVIGGDATEP
GPYHDAHTFMRDLFEHDHGLDTVGVAAYPDGHPLIGEDERRHALFAKQELLAEAGLRGYC
STQMCFDPARIIAWLKGERSDGLTLPVHLGIPGAVERAKLLTIGARLGVGQSLRYLHKNR
RSMAKLLGSSAHDPSELLEALSSQLTPLGINGLHIFTFNQVETTASWRHALIHG
>A0A143J1J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MTKRTPISFEFFPPKTDTGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGEHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>A0A6M0XVA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sporogenes|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSITTIYETLEELKDLTPDFISVTYGAGGSLKDNKT
CELSSLVKNKYGIEALAHLTCINSTKEDIDLIIKELKENNIENVLALRGDIPKDKDIIGE
YNYAFKLIEKIKENNNFGISGACYPEGHIECKSLDQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLNKTQQKSINVPIQAGIMPVVNKKQIERIVKISGATLPKKFMKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A2X1KBE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKIL
SREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0G9FM24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A069JHU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus qingshengii|TrEMBL
MTFDPVRGRSSEGWATRTPSIVDRIASSTGSRIPFSVEFSPPRDADAEARLWRAVRTFER
LGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSHSTEELRAMVGAYADRG
ISNILVLRGDPPGDPLGEWKKHPEGVEYAEELVRMVRDLGDFHVGVASFPEGHYRAPDLA
YDTKYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVSAYDAEQGAKPIIPEIMPVTSLRSV
RRMLELSGSSLPPALERRFDAAAGSGPDENRAAVRELGIDLATEMGERLIAEGAPCLHFI
TLNFARATSEVLERLGLTPDTSVGTAQAV
>A0A264VTJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia rettgeri|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSEEMEQTLWKSIDRLKNLKPQFVSVTY
GANSGERDRTHSIIKDIKDKTGLIAAPHLTCIDASPDELKAIARDYWNNGIRHIVALRGD
LPDNSRKPDMYAVDLVELLKSEADFDISVAAYPEVHPEAKSAQADLISLKKKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKLTNVRIPAWMSKMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRP
>A0A536GBL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAELLRAPRYEVLPTDNAAELVAAYVPREVTITVTASPRRGMPRTIHLAVALAKLGYHAV
PHLSARLIHDRVELGQILVALKDAGIKNVFVVAGDSREPAGLFPDALSLLAALPPDHGLT
EIGVTGYPESHPFIHDDMTIQAMWDKRRLATYIVSNMSFDPEGVKRWVGRVRNRGVELPI
YIGMAGVADPARLMRLSTKIGLADSARFLRGHPSWVARMFRPGGYEPGRFVNALLPDVAM
PERRIAGLHVFTFNEIEPTERWRREMLAEIR
>A0A0K5I128|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRIIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A737MY62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Paratyphi C|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3D2TXR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MLYQGNIRDYLSKQPLLFDGAMGTYLADKYIQFGGESCEKWNLRYPERIKQIHKEYIDAG
AVAIKTNTFAANAGDHFTAEEVGKVIAAGTQIARGAIEESAGEQILFGDIGPVLIGDEND
AAERYRLPVDCFLEQGVRHFLFETLDNIEGLDEITEYIKQKQPEAFIIVSFAVSPEGLTR
SGCYGRSLYQKMMNVSSIDALGFNCISGPKHLLDLMYKLSREQNTKYISIMPNAGYPAVL
DNRTYYEAHHYYYAKEMYQIAKQGASIIGGCCGTDPSFISEIAKTLQQSPLPGRKTYSAD
GSGRSVNSVVENRQTEQSIPVANDGQEVKNYAGKDNLRNTFAAKLACGEKVLVVELDPPV
TPEIDFFMEGAAKYQQAGVDAIDIADCPVAKARIDSSILACKVMRELGLTAIPHMTCRDR
NINATKALLLGLNVEGVNNVLTVTGDPVPAAERGLVKTMFSYNSAVLANHIRTLNEQIFQ
NNPFMISGALNVNAVNFDSQIIHAKRKISQGIAVLFTQPVLTERALNNLKRAREELDVKI
LGGIMPVVSYRNACFMNSEMAGIDVDPRIIEMYQDKDRAQGEELAEQISAQVAQEIAPYV
DGFYLITPFKRVELILRIIKQIRGLLDR
>A0A6B4GX56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNEKKLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELKENNIENILALRGDIPKDKNIIGE
YNYAFELIEKIKENNNFGVSGACYPEGHIECESLKQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLSKTQQKNINVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A6B4GTV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MHIKELFNEKNLVFSFEIFPPKVTSSIKTIYETLEELKDLTPDFISVTYGAGGSLKNNKT
CELSSLVKNKYGIEALAHLTCINSTKDDIDLIIKELEENNIENILALRGDMPNDKNIIGE
YNYAFELIEKIKENNNFGVSGACYPEGHIECESLKQDIRELKRKVDAGAEHLISQLFFDN
NIFYEFLSKTQQKNINVPIQAGIMPVVNKKQIERIVKISGATLPKKFIKILDKYEYDKKA
MEDAGIAYAVEQIVDLVSSGVKGIHLYTMNNPYIARKITESTKSIFNSINKDVAV
>A0A6B4RFD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium botulinum|TrEMBL
MNIKNLFKDKKVVFSFEIFPPKTTSSIQTIYDTLDDLKGLNPDYMSVTYGAGGSVKNNNT
IELSSLIKNKYGIEPVSHLTCINLTKKDVEYYLREFEKNNIENILALRGDVPIGSKITGE
LNHANELIKYISDNGNFNIAAACYPEGHIEHKGLYREIESMKRKEEAGVSYFISQLFFDN
NLYYNFQDEVRAANINLPIEAGIMPVTNKRQIERILSLSGASLPDKFKRIMERYEHNPEA
LRDAGIAYAVEQIVDLISTGVDGIHLYIMNNSYVAKRISQSIESILLTVNQIQ
>A0A6M7V595|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. NZP2077|TrEMBL
MIGRQRDENPAGIDLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETVRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRNNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A0H0Y7J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio alginolyticus|TrEMBL
MGYTHAGHIDALNQNIAELSDNINVSFEFFPPSSAKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKATTGLVAAPHLTCIDATREELINIADDYWNNGIENIVALRGD
IPPGGGAPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPGWMSKQFD
GLDDDPVTRQLVGASQAIDMVRVLSREGVKDFHFYTLNRAEMTYALCHTLGVRPRAVVGA
>A0A0C4UTD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Araucaria humboldtensis|TrEMBL
AYGIHLGTEMCKKILAHGIKTVHLYTLNLEKSALAILANLGLIDMTKIKRPLPWRPPANV
>A0A5F2D5G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira meyeri|TrEMBL
MHISQILGKKQTTISFEFFPPKNAEASEDLFRNIQELSQMNPAYVSVTYGAGGSTRDLTH
DLVVKLQEETGLTIVSHLTCVGSTKDEIQEILKRYQKSGIHNIMALRGDPPKGQAEFHKT
ENGFEFAGELVGFIKKEFPEMGIGVAGFPEGHPSTPNRLKEIEYLKWKVDQGVDYICTQL
FFNNNVFYDFVERCEIAGIKVPIIAGIMPITSRKGMARMAELSLGTNFPAKLLKSLSRAE
DDVYAENVGIHWATEQVRDLLDHKVAGIHMYTLNKSKATRRIYESLGIRNFDSIV
>A0A1V3ITF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rodentibacter trehalosifermentans|TrEMBL
MSYAKEINNLNQNIVDFNKKINISFEFFPPKNEKMENMLWESIHRLKVLEPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDASPEELKQIAKDYWDSGIRHIVALRGDEP
KGYEKKPFYAADLVALLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIESYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPTWLAKAYEGL
DNDPTTRNLVAASVAMDMVKILSSEGVSDFHFYTLNRSELTYAICHMLGIRPHVTK
>A0A1E7YYA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidithiobacillus caldus|TrEMBL
MATRCEFSVEFFPPKNPAGEAKLRETIGALQALRPDYASVTYGAAGSTQERTLATVAMLA
RDTELEAVPHLTCIGSTEAGIRAILEHYRELGIRRIVALRGDLPPDREDPGFFHQALDLI
AYIRAFGGFQIYAAAYPEFHPRAVHARADLEYLQRKVEAGASGLITQYFYNPDAYLQLRD
DLARRGVDVPITVGVMPMTNYAQIANFSAQCGAEIPQFLRRRMESFADDPGAQAELAIEV
ASRQCRLLLDQGAPGLHFYTLNQAEATLAIARNLGL
>A0A5I1MAH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Cotham|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A3D2RGI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter sp|TrEMBL
MSIIPRVSFEFFPPKDIEASFRLWDTVQMLAPFQPGFVSVTYGAGGSTRALTHQAVTAIG
RKAGLNVAAHLTCVAAPREETLDIARAYHAAGVRDIVALRGDPPKGKSGFSPSNGGFASS
VELIKALAQTGDFNLRVAAYPEVHPDSQGAARDLDWLKAKIDAGATSAITQFFFKADTFL
RFRDRVLAAGIDFPIIPGILPVENWAGVKAFAKRAGSLIPPVLDAAFSVAARDGREELLS
LTHCTQLCDQLLSEGVEDLHFYTLNRPQLTRDTCLALGLKAKSTLQMVA
>A0A0B5S6W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>C6KVN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MSLPLSLEFFPPKTPEGVEKLRAVRQKLYALEPEFCSVTFGAGGSTQEGTLDTVRDIVGE
GRRGVPHLSCIGQTQESIRQRLSIYREAGVKRIVALRGDLPSGYGIGGEFRYASDLVAFI
RGETGDHFKIAVAAYPETHPQARSPQADLDAFATKVRAGANMGITQYFFNADAYFHFVDE
LRRRGVELPVVPGIMPIATSTQLLRFSDSCGAEVPRWIRMRLESFGDDSASIKDFGADVV
TAMCERLRAGGAPSLHFYTLNQAGPTLEVCRRLGLA
>A0A3M5SKI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas savastanoi pv. glycinea|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A6J6MRC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MERMTVSVEFFPPKDDAGEARLWEASAALESIAPDFISVTYGAGGSTRDRTIKITKEITE
RTGRNTVAHLTCVGSTKEELVEILAQYRSAGIKSILALRGDPVGGPAANWVTTPGGFDHS
DQLVELAIAQGGFEVGVAAFPDGHPASNNNLDRDIKVLLRKEELGATFATTQFFFESSKW
ESLVEKLATRGSKLPIIAGILPVTNVKQLHRMAELGGTPIPEKISKLFSEISEDPDAVRK
AGVDLATKLCAELIAMKVPGLHFYTMNTASATLEIYKNLGLPSRG
>D8L133|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema primitia (strain ATCC BAA-887 / DSM 12427 / ZAS-2)|TrEMBL
MKVSEILKTKKTFSFEVFPPKEKDGVPKLQKELDQLFQMKPDFISCTYGAMGTNVGESKE
ICKYIVDHKVNCVTHFTCIGKTAAELKAIFAEYVAMGLENGLAMRGDFQKDPVTGDIKSS
TGGEFEHANQLISFLHKEFPQVCFAAAGYPERHLLASSLESDINYLKAKQDAGAELIMCQ
TCHDIPAYEKWVAQCRKAGIKLPIVIGIMPILSRRNAIDMTIPGAVPVELSRIVGQYSPP
PPPPKSASEETLKQYDDLVKKYAGEFEKYGMEYTINEVKNYLKTDLQGVHFYALNKAEKV
IKIVNDGNLIALCK
>A0A439VLK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETAIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A8H2WHV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKLSEKLANHTSDAPYFTFEFFPPRTEQGYSNLLTRITGLASLKPIAASVTWGAGGSTRD
RSLDLAAFCQAENGLDTILHLTCTNMEKGTIDEALTTAMEKGVSTVLALRGDPPRGEEYW
IPTDPRFQHAEDLVTYIKQHPKFGNHFCIGVAGYPDGHSEGGSEEEQLTHLKRKVEAGAE
FIITQLFYDVEKFKSWLRKVRNTGITVPVIPGMMPLQTYATFTRMTDLCKATVPQHIQAN
LDAIKHDDQLVKEYGASLAVSMIRSILVDGDVKGVHFCTLNLEKSVRKILDELGWTHGTH
HPNQIITDASQSPHILPAPADAPHPVTFTISPSEATQHAATSLAEHTRTGTLRTAAEAIN
SGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPPHVAISQWGRPTTEQDLADLFLAYLNH
KAPTTPFSPTPLSDESITILPHLISLTSKGLWTVASQPAVDGILSSDPVVGWGPKDGRVF
QKSFVEFFATEEELVKIAKAIEDSGDGWVTFFAGNNDDGFLSNIPDSGSNAVTWGVFPGQ
EIAQPTIIDRDSFLAWKASIYTWTMREIAIEYMEQDDAFMIWHDFGLCYSPDSPTRKLLE
NVTKTRWLVSIVHHDYKDPNALWDFLAKHLN
>A0A4Z1R2E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium salinitolerans|TrEMBL
MRSETARRDGDIRLSFEFFPPKNAEMESQLWETVDELKKWNPDFVSVTYGAGGSTKAPTL
DAVRRMIADGHLPTAAHLTCVDASRDEVHQVVEEFRNAGVRHFVALRGDPSTGIGTAYQP
HPEGYENAAALVKGLREIADFEISVSAYPEKHPESASEAIDIDMLKRKADNGATRALTQF
FFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYDD
DLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A6P3DGT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bombus terrestris|TrEMBL
MKKFVSKHKVRDSGIDDECDNIADHFRSIDTKREMIDLRKKLQDIINIDAIFCSFEVIPV
ISKDLLQSFFTEMNKYHPLFYALTWHKNDMKDYLSLDIINILPNNTLLHLIAKDLTSTDV
KIILKEALEHGIRNIFVLRGDSTKSNSEFSHAIDLVRFIRNQFGNIFCICVAGYPEMHPE
SSSKEMDLIYLKEKVDAGANFIMTQIVFEASIFIKFVNDCRNIGINIPIIPGIFPILNYT
CLQKMAKICNIKIPKIILNTLECIKDNDEEVHNYAVEIATNIIKKIIASKTACGFHFFTL
NKPSLSLEICDKLNIFH
>A0A412JP91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides uniformis|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIREVAKQIY
>A0A442I7Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQSARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A107L039|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia cenocepacia|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQSRSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLIDAGVPGLHFYTLNAATATRTICERLAV
>A0A485LAE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces stellatus|TrEMBL
MKIIDKINEKIEKKEAFYSFEYFPPKTAAGVTNLYSRMDRMAAMEPLFCDMTWGAGGSTA
SMTIEISSNAQKFSGLEMLMHLTCTNMPKGSIKNALDSAKDAGIQNILALRGDPPRGQTE
FKECEGGFSYAIDLVKYIRQEYGDYFCIAVAGYPEGHSDCKDLDTDILHLKAKVDAGADF
IVTQLFYDVPKYLEFVAKCRAIGIKVPILPGIMPIQSYGGFSRMSTMCGHIPEEIVSALE
PIKDNDEAVKDYGVQLGIQMCKELLDAGVPGLHMYTLNLERSTRLILEGLGLNALSRREL
PWRPSTLAKRAGETVRPIFWANRPKSYVDRTSTWDEFPNGRWGASESPAFGDLNESYYLH
TTASVQERKAMWGESPVTVEDVYETFTRYVMGALKSLPWCDTPLHLETKSIQERLAAVNR
AGFLTINSQPRVNAAPSDDPMFGWGGPGGHVYQKAYVECFVSPENLKRIIEKCNKMKHVQ
YHAVDVHGNSYSNCGKGTTAVTWGSFPNKEILQPTIVDTDSFMTWKDEAFSLWLSMWASL
YNDESAAHALIHQIHDTFFLVSIVDNNFVNGNIWDAFDVDVAAPSTAGP
>A0A3S3IT82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDDMEARLWDTVTRLEPLKPQFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIREFADFGVTRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLEKDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A441VMQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>Q9F1R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus elongatus (strain PCC 7942 / FACHB-805)|TrEMBL
MNMRRFREAVAAGEFLITAEVAPPKGADPSGMLAHAELLRSRVHAINITDGSRAVMRMSA
LAATALLRQQGIEPICQFACRDRNRIALQADLLGAQALGLDNILALTGDPVKAGDSPEAR
AVFELESVRLLQLIQKLNSGLDIHEKSLPDGASDLFVGAAVDPQLKSWSGLERRFWRKVD
AGAQFFQSQLICDFDRLDRFMEQIARPSGRPVLAGIFLLKSAKNAEFINRNVPGVQIPQT
IIDRLAAAADPLAEGIAIAAEQVRWAQQLCQGVHLMAVRREDLIPAILDQAGIAPLQPSS
DRQSSTLLMS
>A0A440DCE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGRFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKAFMQSARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A4R9L5J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira stimsonii|TrEMBL
MNKILLEVVPRDNETLLKEVNYIKNNFNQISGINIPDLLRFETRSWIYATLIKNVYSKAI
PHLRAIDFDIDNCEYIIEYLQTNQIESVVVIKGDPPTDMSKKVFPTTSVKLIKKLKKEIG
HLKVYAAIDQYRSGIKEEFDYIEMKKDAGADGFLTQPFFDLRLIDIFTEKLNGTEVYIGI
SPVVTEKSQSYWESRNRAYFTKDFKPTLDWNVQFAKDVISYCSKNELNTYLMPIRINLES
YLTKIFT
>J8JNS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VD107|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVSAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQDGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIAGMKRAIANIAPVIAKETIPRPKVVH
THEKRSRAHVTLAEKTKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIKEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQQLIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEVKEGIN
>A0A7C2WT35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Hydrogenedentes bacterium|TrEMBL
MKLADLYKAQGLVVSFELFPPKKWRGMAKLFEHFNELAACHPSFVTCTYGAGGSTSTRTL
EVLEWIRGDYPEIPVALHLTCVGLTTPELRAYVDDAVNRGAQGIVALRGDPPGGGPFTPT
PEGLRHANELVALIRAAHPDLTILVGGYPEVHPEAPSPEADLENLKRKVDAGADVVLTQL
FYDNALYFRFRDRCEKAGIRAPVVPGILPVTTLTQVKRITSLCGATLPQRLTQRLETYSN
DEEGQFAVGVYYATRQVEELVEQGAPGIHFYVLNKSRAAALICRALTLDHLAP
>A0A838EA41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euzebyales bacterium|TrEMBL
MQTYVRDLLAGEGPSFSFEFFPPKSDEGERVLWRAIRELRPLQPTFVDVTYGAGGSTRDR
TLRVVERIARETDIPVVAHLTCTGTSVDEVRAVLRSLGEAGIRNILALRGDPPGGASSPW
EAHEEGFHHAEELVRLVHEEGDFCVGVGAFPELHPESADRDTDIGFFARKVSAGADFAIT
QFFFDPADYFRLASDVRDHGCEVPIIPGIMPVTNLSSIERMAELSGAAFPTDLGERLRAV
ADDPAKVRAIGVEVATELCRELLDGGAPGIHFYTLNRSTATREIYTNLHPGHA
>A0A7S3H5C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spumella elongata|TrEMBL
MAQQYADDKKVSDLIAQTKPGWFSFEYFPPKTDEGVKNLHKRINRMATLGPLFTDFTWGA
GGSTSELSLQLTSWAKNEAGTVSNMHLTCTNQKSEMCGDALTQCKKVGVRNIVALRGDPP
RGSEKWGATEG
>A0A7Y3GWG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcales bacterium|TrEMBL
MGRFRDRLEAGDFVVTGEFTPPKGTDLSEIAEKAELLRDFVDAVNLTDSHRARMTMAPVG
AAKILLERGVDPIVQVTGRDRNRIAVQAELLAAASLGVENLLCMSGDNPAAGDHPDAKPV
FDLEAIGLLRAVAALNAGRDLGGAELSGTPQFCAGAVANPGADDLETELGRLEQKLSAGA
RFFQTQPVFDIDRFETFSAHAESLGAAIIPGVLLLKSAKMGRMLNENVPGIHIPESTLKR
LESSDDRRATSVEIAAEIVAALRPIASGVHFMAIGWERHIPSVLEAAGAR
>A0A0L0VX76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Puccinia striiformis f. sp. tritici PST-78|TrEMBL
MKISQKLAAAESENRISWSFEYFPPKTDNGLTNLYDRIYRMSQLGPIFIDITWGAGGSTS
NLTTEFVKTAHEQFGLETCMHLTCTNMPKEKIDTALKEAYEFGCENILALRGDPPKGSTE
WTATEGGFEHAIDLVRHIRAGYGDHFDIAVAGFPEGHMHSSLTKEQETIYLKEKIDAGAN
FIFTQMFYDVDIFIDWVREIRAAGITVPVIPGLMPIQSWAQFKRVTNFSKTIVPQYFLDT
LEPIQSDDQAVREAGTKLVADMCRKILNSDLGIRILHFYTMNLERGTKMLLDELNLNPSR
DITNPLPWKMSLLGKRRSESIRPIFWANRAKSYLSRTETWDEFPNGRWGDSRSPAYGELD
GYGININSATIETLKGLKKFPTSLEDLARIFANYCGARFPGEEPVKYLPWSDIALSEETG
KIEDVLVKINKRGFLTINSQPAVDGAKSSDPVHGWGPRGGYVYQKAYLEFFCCPEKFQSL
TERLEQDPDVTYYAVTKTGDLVTNNTRPGPNAVTWGVFPGKEIVQPTIVELVSFIAWKDE
AFELGHQWAELYKDTAPESSKFIHEIMDSWYLVNIVNNDFRKSNDDSENSALFQFFGPEP
VIVKEDGVPSTNGFHHSNGISKVNGTSVTVNGLNGDINNLAI
>A0A094CTJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4516|TrEMBL
MADSATTDKITDKIAALPQDASYFSLEFFPPKTAMGSTNLRARLDRMSRALRPLFVTVTW
GAGGSTASRSMELAELCQRDLGLTTCLHLTCTNMSRALVDDALKAAKEAGIQNILALRGD
EPRGEYKDALEAGKEGEDEFVWAIDLVKYIRKKYGDYFCVGVAAYPEGHADGSHPTEQSL
EHDLPYLVDKVKAGADFIMTQLFYDVDAYDKFEQILRDHSSGAFKTLPIIPGLMPIQSYQ
ILRRTTKLSNAKLPQSIIDRLDAVRTDDEMVKKVGVDIVAEIVESVRHTKSRTKGPKGFH
FYTLNLEKAVAFILERANLIPSFTPVLTSDVFVDDITDTIPLPQLLINGERKSRRQSSVG
SGPHNFVIIDREEASGFETTGAEAAVPKDGVNTRANTLAISEGEGALGREATWDDFPNGR
WGDARSPAYGEIDGYGPTLHTSPAEALALWNHPTSRTDISSIFVQYLNGTLSALPWSDEP
ITAESGLIKDELVKLNQKGWWTIASQPAVNAARSQDEVVGWGPKGGWVFQKAFVELFVPT
SDWARLKTLLEGNAEVSFLAQSASGEFLKSKLDLGPGEEGSETNAVTWGVFPGKEIVSPT
IVEEVSFRAWAEEAWQMWREWAAVFGKGGDESRRFLDGVAKDGWLVNVIWHDFVGMCKAK
EGRSEEEEYKGLWDVLIEA
>A0A1C4D0F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia sp. v-85|TrEMBL
MRPAPYTVRVTPTAPAPSIVERLSAPHRGPVPFSVEFFPPRDAEAESRLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSVAELRALVGAYADQGIT
NILALRGDPPGDPLGEWVAHPDGVEYAEQLVRLIDTLGDFHVGVASFPETHHRSPDIEHD
TRTLVSKLRAGAEYSITQMFFDVEHYLRLRDRVAAADPEQGLKPIIPGIMPVTSLATVRR
MVELSGSVIPPDVEERFAKAAGNGAEEDRASVRAVGIDFATEMAQRLVAEGAPCLHFCSL
NFAKATTEVLGRLGVDVDAALHVPA
>D6H8G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neisseria gonorrhoeae DGI2|TrEMBL
MNYAKEMNALNNSLSDLKGNINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGA
NSGERDRTHGIVKRIKQETGLEAAPHLTGIDASHDELRQIAKDYWDSGIRRIVALRGDEP
AGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFCFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPKWLSQMYEGL
DDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGARP
>F5LW59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis 315-A|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIHSKRPDLPILGACYPEKHPEAVTLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKAGINVPIEAGVMPVVNANQVKRMTKMCSSKISEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A7W3VV29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis dendrobii|TrEMBL
MTSVIERLRGDGPAFSVEFFPPRDEADEAVLWKAIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLCPMAHLTAVDHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPEGLTYAEELVGLVRSLGDFCVGVSAFPYGHPRSADLESDTKHLVRKFRAGADFAIAQ
LFFEAEDFLRLRDRVAAAGCDALVLPGIMPLTTLRTLHTTIKLSGAPASQRLLDRLEPFS
DDPKAFRAAGIDWVTELCEKLIAEGVPDLHFYTFNRSKATREVVTRLGLVPARTY
>A0A1Q7R3M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium 13_1_20CM_69_28|TrEMBL
MTITLSDLLKDGKVHVLDGAMGTMLYSKGFLLNVCYDELNLKQPKLVQEVHEAYVRAGAE
VLETNTFGANPVKLRSFGLADETEQINQAAVRLARAAAAGRASVVGAIGPLGVRIEPFGA
LARDEACAHFSRQVKGLLAGGVDGFILETFSDVEELHAALRAVQGLSDLPIIAQMTIGDD
GLTHYGTGPETFAQQLTEWGADVIGVNCSVGPAGVLEAVEKMVKVTDRPISGVPNAGLPR
DVGDRKIYLASPEYMASYARRMIEAGARLVGGCCGTTPEHIKKIRDYVASVVPRHQPAVV
SRETIAVPAGVEEVPLAARSRWGAKLARGELVTSVEIVPPKGVDATPMLEQCRALKAAGV
DAVNVPDGPRAQSRMGVLPSAILIEREVGIETVIHYCCRDRNLLGMLSDILGAHAAGLRN
ILIITGDPPKMGPYPEATAVFDIDSIGLTNLVFRLNHGLDPGNNPIGAPTRWAIGVGVNP
GAVDLDRELSRFAWKVDAGAEFAVTQPVFDPAQLEAFLARVGQFKIPIVAGIWPLISLRN
AEFLANEVPGVSVPESVLTRMRQAQEKGKEAALAEGVKIAREMFQQVKGSVQGVQVSAPF
GRVEVALEVFG
>A0A7L5YGB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiobacillus sp|TrEMBL
MTERTFSFEFFPPKTAEGTEKLRATRKQLAQLNPKFFSVTFGAGGSTRDRTLETVCEIQA
SGSEAAPHLSCIGSTEASIRDILNAYKRQGIRHLVALRGDLPSGTMDAGEFNYANELVAF
IRKETGDWFEIEVAAYPEVHPQARSATEDLANFKRKVDAGANSAITQYFFNADAYFNFVE
DARALGVAIPIVPGIMPIGNYVQLARFSDACGAEIPRWLRKKLETYGDDLASIRAFGLDV
VTDLCDRLLAGGAPGLHFYTMNQAGPSTTIWQRLGL
>A0A8D5YK90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes sp. L3-i22|TrEMBL
MSLGLPSKLPGTPAIGELIRGSAPTFSFEFFPPKTPDGERLLWQAIRELESLRPSFVSIT
YGAGGTTRETTVAVTERVATETTLLAMAHLTAVDHSVADLRNVIGRLAGAGIRNVLALRG
DPPGDPMGAWVRHPEGVDYAADLVRLIRESGDFSVGVAAFPYKHPRSADVAGDTRNFVRK
CRAGADYAITQMFFDADDYLRLRDRVAAAGCDTPIVAGVMPVTRMATIERSTQLSGAPFP
PALLREFERVAGDDAAVRELGIEKCAEMCARLLDEGVPGVHFITMNRSTATREVWQRLAP
ADVAAAA
>A0A1I5USH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldicoprobacter faecalis|TrEMBL
MIKEYLQDNILLADGAMGTYYSQITGEDAAFSELANETEPEVVKAIHAEYIQAGARLIRT
NTFSANTLALDVSRDQVKRIIAKGYEIALQAARGREVFVAADMGPIPEMTADKKEVDPEF
ILDEYRFIVDAFIEAGADIFVLETLSSTDYLREVTEYIKSKNSQAFILVQFATTVDGYTR
KGISISRIIKEVKAIPYIDAYGFNCGAGPAHLYQNIRAFDFSGDIVSVMPNAGYPEIVHQ
RTVYTRNPEYFSNIMMDVARLGVKIVGGCCGTTPLHISKMRDKLAEFAGEKRRASAPVRK
VWHITMGKNDFYTKLVEGKFPVVVELDPPFDVSVEKIMEGAAVLKQNGVDAVTVADSPLA
RPRLNSMMLAAKIKREVGIEVIPHLCCRDHNLIGLKSLLLAGYVEGIRNLLVVTGDPIPG
AEKSSVKSVFDLNSFKLMALIQEMNNELFSQDPYIVGGALNLNVQNRDAEISRMERKMEN
GARFFLTQPVFASEVIEYLARLKAREKVKILGGVMPIVSYKNALFLNNEIPGISIPSHYI
ERFRPDMDRQEAEEVGIEIAVELINNIKQHVDGLYLITPFNRVNMVVRVLKGSLL
>A0A7V5R3W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MQRTLAMHMKNNGTKNSFFQSLLDRKTFTLTYELVPGRGAGGKKIDRLLEFAHRANKDGR
ITALSITDNAGGHPSLAPVAIGSEIQRIGLEPLIHFSLKDKNRNQIESHLFLYQRKRFHN
LLILGGDFPKATYYGQAKPVYDLDSIQTIQLIERMKAGHYRHVHGNNPHALPFSFQCGCV
VSPFKMTEAEQVWQYAKLLKKIRAGATFIITQVGYDLKKYEELVRFLSDHKVRIPVLANV
FIPSPAVAKFMAQGGVPGILLPPALADLMQSEKKEDRLLRAAGMAAGLRKLGFAGIHLGG
NGLDFDDVALVLDQAEELYKKDAIAPAGIDFPIAHGWSLYRPKGKQHNRLHPGTRPGARP
LHHLVHRLLFSGTNPLSISFAAFCRLCDRHTISRRLLIFAERIIKEILFNCRMCGDCTLP
ESTYLCPQSGCPKKLVNGPCGGSNGGRCEVFPDRRCFYVRVYLRLDQKTTLEDLAGAPIL
PPKDWSLEHSSSWINYFQGRDHTTPKAD
>A0A2S6TEP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha3_Bin6|TrEMBL
MTNQLDSPPIESQLVRRLLGGQFALTAEVTPPVSAGSDELLAKAEPLRGIVDAVNVTDGA
SARVHLSSVISAAILNANGIEPVVQFTCRDRNRIALISDLLGVGAQSIHNLLILTGDDPT
VGDQPQAKPVFDLKSHELITIAHKMSQDGIIPSKSVKMTAEGVDPNTRKIETPPKFFIGA
ADVPTVKIDEQWLVGLRKKKACGAQFIQTQLSYDMDLIRAYANLLIEEGFTENMFFLIGN
GPLPSARSAIWMRENLWGVVVPDKIIKRLETAKDSKLEGIRICSEHLQELSQISGVAGAH
LMAPINVKSIPASIEMASLGNRS
>A0A3N5F0D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium|TrEMBL
MSFQKRLQSNEFVVLAEMHTPKGVNISRLVTDARRIKGRVDAVVVPDMDNGIMRMSALAG
GVLMQQQGVETIMHVYCRDRNRMALQGDILAAHVLGIQNLIVVHSEDMSQGDHSDAKPVY
DLDEIGLIKAIGLLQKGKDLAGFDLDGEPSFITGCSIASYADDAALAAELSVAREKVAAG
ARFIITPPVFDLQHFTSFLAKVKELGVPVIPTVFLLKSLAIAQYIANSEPGAHISEELIR
RIRKSPDREQEGILIAGETIAALKAMTQGVLIQTLGWEHKLPAILDIAGL
>A0A416ALZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF43-10|TrEMBL
MIQEKEHKGVVFSCEVFPPKRDDDIYQIYKTLDEIKTLKPDFISVTYGAGGSNSKKTATI
AAYIQNICEVEALAHMTAVGMDEASLRALLFELKKKGVENILALRGDKPRTMSQEEFDRR
YFKYATDLIPEIKKNGDFFIAGACYPEVHPESKNQEEDIQHLKQKVDLGLNCLITQMFFD
NNAFYSFMDKLEKAGIDIPVHAGIMPVTAAKQLGTSVTLSGSSVPVEMSNMIAKYGENPE
DMKKAGIEYAVNQILDLKKHGVAGVHIYSMNKADVTKQIYEASF
>A0A414TNW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium varium|TrEMBL
MKISELFKRKKTIVSFEVFPPNSIYSLEDVYSSIDELAKLQPDFISVTYGAGGATRGNTV
EIASKIKNNNKIEALAHLTCLGAKKNEIDDILKQLRANNIENILALRGDKPKDCTPIGEG
DFKYAQDLISYVKEKREFSIGGAYYPEGHLETNDLLDLFNLKRKVDSGTDFLISQIFFDN
ESFYRFRDKLNKLQINIPLVAGIMPVTNAKQIRKITSMCGCSIPEKFQKILNKYENNTQA
LKEAGTAYATEQIIDLITSDIDGIHLYTMNKVDTAKKIMANIAHIREISGGNR
>A0A0D0CRA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gymnopus luxurians FD-317 M1|TrEMBL
MKVTHKIAQCEQENKIWWSFEYFPPRTAQGLQNLLDRIERMRGLGPEFIDITWNAGGRTS
ELTAEMVKTCQSLIGIETCMHLTCTNMPKEKVDIALREAKISGCRNVLALRGDPPMGKDE
WEAVEGGFVHGIDLVRHIRREYGDYFDIAVAGFPQHQSLPPAELEFEMKCLKEKIDAGVD
FIFTQMFYDVDIFIAWVKTVREYGITVPIVPGIAPIQTWNGFQRATSLAKTVIPQSVMDA
LEPHKANDEKVREIGTKLVAEMCRKILDANLGIRGLHFYTMNLEKGTKMLLEELNLVPRL
ETVKPLPWRQSLTPTRRQETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGISIKQSKSEARALWGEPSSFAEIASLFARFCKGTLSALPWSDQKPSIETSVIADQLA
KMNELGFLTINSQPAVNGARSNDKIFGWGPRNGYVYQKAYLEFFVQPALLAHLLSHIERD
SNITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIVQPTIVEAVSFMAWKDEAFELGLQ
WARVYDADTVSAKLISGLMDTCYLVNVVHNDFHDANAIFLPFFQAGEEYKASQTKMNGVT
PNGNPSAP
>A0A2U9P0B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces actuosus|TrEMBL
MTTFSFEFFPPKSEQGERVLWEAIRRVETLHPDFVSVTYGAGGSSRDRTVAVTRRIAAET
TLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGDPKGPWTPHPDGFTHAWQ
LVELVRSLGDFTIGVAAFPEMHPRSPDWESDIRHFVAKCRAGADYAITQMFFHVEDYLRL
RDRVAAAGCDIPIIPEIMPATDYRQIRRFAELSDAAFPEDLARRLHAARGNPAAGHRIGV
EYATAMAERLLAEGAPGLHYITLNKSTAALDIHRTLQIPRSVSVR
>A0A0R1VQZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Liquorilactobacillus ghanensis DSM 18630|TrEMBL
MSSFEETSGLSFEVFPPKTAVSNQKIYQTLHDLQDLRPNFISVTSSNRTLNFENSTLKLA
DYVQNTLGIPGVVHLTARYFDKSQIDQVLIELKKLGIKNILVLRGDLAPGCPPKKDFNHA
SDLMTYIKSQDSSFRLFGACYPESHPESPDKVSDIHHLKAKVAAGCDCLITQMFFSNDTF
YQFQENCALADIDVPLLAGIMPIVNRAQALHVLKQSECHLPAKFTLMLDRYQNDPEALRA
TGLAYAINQITDLVTNQIAGVHLYTMNQPAVARYIYQATKSLFTATCSPY
>A0A0N7LUJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobius gelatinovorus|TrEMBL
MAVAASIEIPPARVLEMQDLAAVLPKGVRVYLPELGTDNNETFVAAACALRAIGAEPVPH
LAARRIASHAALEARVARLASEAGVTDVLVLAGSPPSPEGPFADSMKILETGVLDRHGIT
HIGVAGHPEGSPHFTDEVVQNAMRWKADFAMRSDAEMRIVTQFGFDVAGMVRWSEEIAAS
GITLPVHLGFAGPTKLRAMLRYARSCGVGPSMQVLTSRGNALLRLFAGYAPEPLVRELET
ALARMKTGNIAQIHLYPFGGSERTANWLRARGSWPEISA
>A0A0E4C8E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas zehnderi OL-4|TrEMBL
MKTSAIFKYKKVLSLEIFPPKRTAPIDTIYHTLDELKGLNPEFISVTYGAGGSENNDATL
EIASAIKNHYGIESVAHLPCINLTKSEVLFMLEGLKKAGIENILALRGDVSSEFPPKQDF
RYASDLISFIKQNGDFNIIGACYPEGHSECPSLIDDIRNLKTKVDAGTDQLITQLFFDNS
YFYAFRERASIAGINVPIQAGIMPVVNKKQIERMVSLCGVKLPKKFITMMEKYENNPVAM
RDAGIAYAVDQIVDLIAQDVDGIHLYTMNNPYIAQRIYAAISTLLAA
>A0A089P1V4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus sp. MIT 0604|TrEMBL
MKSKLQQTLEKRSKVITAELMPPRGGSPIRSLKIAQLLKDKVHAVNITDGSRAVMRMCSL
AMSKLLLENGIEPVMQISCRDRNKIALQSDILGANALGIRNILCITGDSVKAGDQQDAKA
VHEFESVRLLQQIQAFNKGIDPTLGELSDKKTFIFAGAAADPSCRNQRSLENRMRKKKEA
GAGFIQTQMVMEKENLIEFCEKISNPLEIPVIAGVFLLKSYKNALFINKYVPGANIPEHI
LNRLKDAKDPLQEGIKIAAEQANDFINIANGVHLMAVKAEHLIPEIIEKADLSLEY
>A0A4T0FPN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wallemia hederae|TrEMBL
MAIRCALASFNTSSQGFVNLKSRLQRLSLLKPGFVSVTWGAGGSTDERSLELAATARELG
LDVLLHLTCTNMEKTRIDSALDRALELGIDNILALRGDPPRGHEYWIESDAGFRHSSDLV
SYIRQRHNDAFCIGVAAYPEMHTDSLDPQDDLKYLKLKQDSGADFIITQLFYDSDAFLRW
LDTCANNGINIPVIPGIMPIQNVPSLRRLANLCQAEIPQVIEEHLEPIKNDDALVKDYGV
ELSTSMVRQLIDRTNSEKDKYKHLALHATHFCTLNLEKSVRRILANLGWSKGLDSSSLEP
NGLTHKTSSSSLERARLGNRLVAENGGTVRDTSDGVPPLSITAHEAALRALHALKHHPPS
EDSGLPSSNKTSSGGNSLWDEFPNGRYGDVRSPAYGELDGWGASLKTSSQNALRQWGYPL
QTSDINEIFKRYINGEVASLPWFEETLDPESNSIKDYLYKFAEKGWWTVGSQPAVDAVES
SDPVFGFGPKNGWIFQKAFVEFWVPEQQLDDLCKRLNGWKDGGYYAGNAKGEMRSNFYDD
TINAVTWGIFPGQEVVQTTIIEDVSFNAWREEAFEIWLEWSMLYSPKSASHQLMKNVHDN
YWLVSVVHHDYKDTNGLWDFLLS
>A0A1B2DWE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus ihbetae|TrEMBL
MKPDLRQAWENQVLIGDGAIGTYLYQLGFPVGISYEELNLTSPEVIGNVHRQYVDAGAQV
IETNTFSANYDKLSKYGLESKVGEINRAGVRIAREAAGRDGYVVGAVGSIRAGRRSNIST
GELKRYFEEQLGVLLSEDVDGILLETFYDVEEIQLALQQVRKLTDLPVICQFAVENIART
LDGFSMQDAYRILSQDGADVIGFNCRTGPNGIMRALETLSGVMNLPASVYPNAGIADYVD
GEFRYGASPEYFGQMAVPFADLGARIIGGCCGTTPAHIAEIASALSGYAPSPLPEVEPAE
INRVVIQEPAESNPPEPSSEPSLVDLVKERHTVIVELDPPRDLDITKFMKGAEALKNAGA
DALTLADNSLAVTRMSNMALGHLVQARIGLRPLIHIACRDRNLIGTQSHMMGFDALGIDH
VLAVTGDPARFGDLPGSSSVYDMTSFEIIRMIKQLNEGIAFSGKPLKQKAKFVVGAAFNP
NVRHLDKAVARLEKKIASGADYVMTQPVYDPELIARLREATAHLDIPIFIGIMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEAGRAMGVQIGKELLDVATKHFNGIYLMTPFMFY
EMSVQLMEYVWEISGRRLSPLFH
>A0A8H9H3J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbispora bryophytorum|TrEMBL
MALGLPSRLPDRVPTVRELLAAGERSFSFEFLPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPRGGNPLDEWVKHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSATIESDTEYFV
QKCRAGADYAITQMFFEADDYLRLRDRVAARGCDTPIIPGIMPVTQMSTIARSEQLSGAP
FPPELAERFAAVADDPAAVRRLGIEHAIEMCRKLLDEGAPGIHFITFNRSSATREVFQAL
HGVPAAVAG
>A0A2E1XDU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvularcula sp|TrEMBL
MNQPEISFELFPPKRPDGIEALLRVADKLAGFDPAFISVTYGAGGSSRERTLGVTSALAE
IAPAAGHITCVGASCAEVDKVLEEYWAAGVKRIVALRGDPLEGIGAAYAPHEEGYAYADD
LIRGAKKIADFDVSVGCYPETHPEARGLQDELDNLKRKIDAGADRAITQFFFEPEIFLRY
RDAAADAGIDKPIVPGVMLQPNFKGLQKMAGLCGAFVPLKISQAYEGLDDDAPARDRATI
DLVSEICTRLVGEGVNAFHFYTMNKSAIAMEVCRNLGLNKDRRAA
>F9ZAP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odoribacter splanchnicus (strain ATCC 29572 / DSM 20712 / CIP 104287 / JCM 15291 / NCTC 10825 / 1651/6)|TrEMBL
MTKVIDIINQKKAPFASFELVPPLKGSDINKLYGAIEPLMEFAPPFINITFHRDEVEFRQ
TADGTFEKVTITKRPGSVAIAAAIMKRFPVEVVPHLICGGASKHQIENDLIDLNFLDIQN
VVALRGDAIPGQKYFVPEPDGHRYSCELVEQIHNMNRGIYLDECLKNAVPTNFCIGVAAY
PEKHYEAPNIDIDIENLKRKVDAGADYIVTQMFFDNTRFYEFAAKCRAAGITVPIIPGLK
PISTQTHIEMLPRAFSIDLPQELMNEVRKCKDNKAIYQVGIEWCTAQSKDLLVHGAPAIH
YYTMGKADNIREILKRTF
>A0A1E5ILN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Endomicrobium trichonymphae|TrEMBL
MKFKEKLKSDKFLITAELFPPKGVDISSFLRRADCLYGLDAVNVTDNQRASMRVSSLAMS
RILIERAIEPILQLTARDRNRISLQSELLGANILGIENVLLLSGDHPSIGECSGAKAVYD
LDTIQLIKTVRLLETGVDLAGKKLQGSPKFCVGAVVNPSVQSVDLQALMLEKKVKAGTEF
FQTQAIFDVQTYKNFFDKVKHLKVKILPGIILIKSPKFLQFLQSMSGINISDEVKDRINS
ASDPLTEGIKICSETIRKLRSFADGVHIMAIGTEEHIPKMIRDSL
>A0A1W6CVA0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus contaminans|TrEMBL
MPVPAVSFEFFPPRTLDQSFRLWETARALAPLGPDFVSVTYGAGGTTRQLTHEAVTALAS
HYGLNVAAHLTCVEATRAETMQIVDDYAAAGVREIVALRGDAPQGAAAWTACPDGFASSV
ELIGAIAARGGFTIRCGAYPEPHPDSAGTAADVAFLKRKIEAGASSAITQFFFDVETFFR
FRDACAAAGIAAPVIPGILPIQSWAGTKRFAARCGTSVPQWAEDAFARAGAAGERALARD
LAVELCRRLTEGGVDRLHFYTLNRPELTAEVCAALGATSRAAAA
>A0A1Y4B222|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. An3|TrEMBL
MKLSSIFKSDSRISFEVFPPKKWEGFPNLYETLNALKELNPSFISCTYGAGGSNSKKTAE
IVSYIQNKLGIEGIAHLTCAALTEDSFLSTIRTFQQMGIHNVLALRGDKPADMTEDSFRS
RTYKHPSDLIPALKDAGFTVAAACYPEKHFEAATMEEDLHYLKYKVEQGADFLISQLFFD
NDIFYRFLDMCRKMEIYVPVEAGIMPITSAKMIGTTINLSGASIPKAMADLLARFQDSPE
DMRKAGIDYAVRQIQDLQAHGVDSVHIYTMNHADTARDICKAL
>A0A0M8SFY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WM6368|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRVEAVSPSFVSVT
YGAGGSTRGGTVKATQEIAADTTLTPVAHLTAVDHSVAELRNVIGQFADAGIRNMLVVRG
DPPGDPMGEWVAHPEGVHYAADLVRLVKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVDK
CHAGADYAITQMFFDPENYLRLRDSVEKAGCETPIIPEVMPVVGIKQLDRLPQLSNAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>X0JNS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium odoratissimum NRRL 54006|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIQDIAQLFVRYLQNEIESLPWSEAPLTTEADEIREELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMITRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKDLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>H1G1W1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodospira sp. PHS-1|TrEMBL
MKSQLRHERTFSFEFFPPKNEEGVEKLRKTWSRLARLEPRFFSVTYGAGGSTQARTLETV
LDIHTHSGIAAAPHLSCIDSTAEQMRSILKTYMDNGLRHIVALRGDLPSGMREPGEFRYA
NELVEFIRRETGDHFTLEVAAYPEFHPQAPSAFKDLENFKRKVEAGADSAITQYFYSADA
YFRFVDDCERMGINIPIVPGIMPITNYKQLARFSDACGAEIPRWIRKRLEAYGDDLDAIR
AFGEEVVSRMCDQLLHEGSPGLHFYTMNQAGPVSAIWKNLGLTPQPE
>A0A1G1LTB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium GWA2_47_8|TrEMBL
MKKLPDIFKTKEKTFSFELFPPKTEEGYQKLLTTVEQLCRLKPDFISCTYGAGGGNRDKT
LDIVEHIQKKHNIISVAHLTCVLSTKEEIKNIITDIKNRGINNILALRGDPPKEQPDWQP
GPDNFKYSSELTAFIRKLFGPHFGIGVAGFPEGHILCRDKDRDAQYLKLKIDAGADFVIT
QIFFDNTFYFEYIKRLKKLNVHARVIPGILPITDYQSLLRFCALCGATVPQEVKRIFEPI
QNDKDATLKEGINFAVRQCQELLKNGAPGIHFYCLNKLSPTDAILTAIR
>N4XPC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cochliobolus heterostrophus (strain C4 / ATCC 48331 / race T)|TrEMBL
MEKITDKINALPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDEALEQAQVLGIRNILALRGDAPRSEE
YRDEDTPPEQDSNKDFTWAVDLVRYIRKQYGDYFCIGVAAYPEGHSDQSHPEHQDPVADL
PYLVEKTKAGADFIMTQLFYDVEAYDKYEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHAKLPTDIIARLDAVKSDDELVKQVGVQIMDEIVEHIKVRPDTCRRGFHFYTLNL
EKAVSHILEDTKLIPSTLIDDDEVIVETTPAINLEPPPNGMMPHRRRSSAVNSGPRNRVI
VSHVSAARSSNPSYEATEEEAGIPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGHPVEKNDISTLFRRHIEGDLEAIPWSEQGLSP
ETLTISKQLLALNAKGWWTVASQPAVNGIKSTDPVFGWGPKNGYVFQKPFVEFFIPASEF
ATLQPKLDAHDQITYFAGNAAGDFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIWREWQRIYPPRSAPSTLLGELRRDYWLVNVIWGDFVNGEGLWEFLLE
>A0A7V9BQG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiales bacterium|TrEMBL
FVVVAGLQVPRGHDVTGFVEQAARLCAAGADLLAIIDPAPPSARVNPVGAGVVLHERVGV
DVMLPMETADRNLPTLQADLLGAHALGLRTVVCRTGNPRVAGDYPQPIAPWEVDSVGLIA
ALSGLNHGVDWRGVPTTDPTSFSIGGSISPSVSDAERELDRAQDKVRAGAHFLVTDVIYD
VEGAVATLAGLRARGEQIPVIASVAPFVDVRTVEWLLHEVPGFSIPPAALAAARIARDTP
ERAVDAAVSAVEKLREFVAGVLVYLPAEPAVPTSPVPTAPVPAVELITALARLRSPR
>A0A2H5Y7J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thermoflexus japonica|TrEMBL
MEKPTLLERLTQGPLLADGAMGTMLYARGFSFDRCYEALNVEAPEVVLEIHRAYLQAGAE
LLETNTFGANRYRLAEHGLEDRVAALNRAGVALARQAAREVNRPVWIAGSVGPLGVPLAP
LGRVRAVEAREAFREQIAALAEAGVDALILETFSSLPEIQEAIRAAQETAPHLPIIAEMT
FAQDGHTLMGHTPEEVVETLLGLGVPIIGANCSVGPAKLLPVIRRMASRVAEAGGPPPYL
VVMPNAGWPEMAAGRLRYPATPDYFAEHAQRFLALGVRILGGCCGTTPEHIAAMRRALEA
RAEPLAGDRPPIFRGVSPPAPAEPEPTDLARRLRAGLFVISVEVDPPRGHDASALLEVAR
SLKAGGVDALNIADSPMARLRMSPWALAFLVQNHVGMETILHFPTRGRNLLRIQSDLLAI
HALGVRNLFVVMGDPPAQGDYPEATDAMDIVPSGLVRLIKERFNAGLDHAGESIGRPTAF
FVGVALNFNAPDPAREIKALRRKIRAGADFIMTQPVYEPAALKDFLRRYEEEEGPIPIPI
LAGVLPLMSLRHAEFLHNEVPGIRVPEAIRERLRRAGEERARWEGLRMAQEAVAELVEFT
QGIYVMPPMGRYELVFQLMEAIPPHRRPGRASHLD
>A0A2S6CQZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cuspidothrix issatschenkoi CHARLIE-1|TrEMBL
MPDTHSFSAFNNFRKAAQAGEFLITAEVAPPKGGDPTHTIEMAATLKGRVHAVNITDGSR
AVMGMSSLVASAILLQHGIEPICQFACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHPDAKAVFDLEAVRLLQLIRNMNQGVDFNHKPLTDGELDLFAGAAVDPQSKSWSGLQS
RFEKKIAAGAQFFQSQLITDFEILEKFMDKIASSYNKPILAGIFLLKSAKNAQFINKAVP
GVNIPDHIIDRLVKAKHPLEEGMKIAAEQVQIAKELCQGVHIMAVKREDLIAPILDLAGV
GKVS
>K7RZW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tepidanaerobacter acetatoxydans (strain DSM 21804 / JCM 16047 / Re1)|TrEMBL
MSLLQKALESGEFAVTAELAPPKGTDFSHALQNAELFGDRVHAINVTDFQSSSLKATSLA
MCKALIDLGLEPVFQITGRDRNRIAIQGEMLSAGFFGVKNLLALTGDHTTVGDNPGAKPV
YDLDSIGILQAATMLASGVDMGGNKLEGSPSFFLGASVTPEYDPIELQLIKMKKKIIAGA
KFFQTQAVY
>A0A428PJ32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium sp. AF-8|TrEMBL
MDRITDRIAALPADGSYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRREE
YRDPDDSEDDGGQDFNWAADLVKYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVEAGADFIMTQLFFDIKAYDHFENTLRDHPSGVFKTLPIIPGLMPIQSYQMIKRT
TKLSHAQIPDDILARLNAVKGDDERVKMVGVDIVSELVEKVKDIKSKTPGPKGFHFYTLN
LEKAVSFILERTNLIPEPPEDEEALVVDDAIPIPALLVNGSSNLRSGSHSRSRASRRHSS
VGSDPHNRVIVGDRPATHPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDF
PNGRFGDARSPAYGEIDGYGVSLHMSITQAVKFWGHPKTRQDINDLFVKHIQGELSAIPW
SEEELLAESSTIQPHLLRLNQKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEF
FIPSSEWSVLKEKLNSSELCDSVCFYAGNAKGDFVSSDKGGHVDGSSGAGPSTNAVTWGV
FPGKEIITPTIIEEVSFRAWCEEAFGIWGEWAKVYGRGSDSEKLLSGIKDEYWLVNLIHH
DFVEKDALWQVLSS
>A0A173J9B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. DR 5-09|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVTEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A3M2AMK3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirae bacterium|TrEMBL
MPSSTSLKAALERGEFAITVELNPPKGTNVTHLLEVAKDLVGKVHGVNVPDNTAAVMRAS
SLALCRLLYEQGHDPVMQVTCRDRNRLGLQSDLLGAHILGIRNVLCLTGDPPTVGDHHDA
KPVYDLDAVQLLRTVQSLNRGRDLAGKELDGGTAFFIGGAVAPEADPLEILHQKLEAKIQ
AGAQFFQTQAIYCPERFAQFMQEARKHRGKFLAGILVLRSYRMAQYLNAHIPGIHVPEAL
CEELRQAGETREQDVGIDIAVRLIQEIRPYCDGIHIMVGRLLPRLSEILTKAKLI
>A0A2E0SM07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomyces sp|TrEMBL
MRLADIFNDPSEQRFSIEIFPPKTDAGEELLMDALVRLKDFGPGFVSCTYGAGGSTRDKT
LQWCEKIQNVLQQTATAHFTCVGSSREELLEWLNQATARGVHNIMALRGDPPAGETVFKA
AEGGLAYANELVSLIREHYPEAGIGVAGYPEKHLEAPSMEEDLDNLKRKVDAGADVLVTQ
MFYNNEYYFRFREACANRDIKLPLIPGIMPITNFARIQRITSMCGTEIPDSLASRLEAVK
GDEEAQFEIGVEFAIKQCRELLDAGVPGIHFYVLNKSQACERILEELNFQTAQ
>A0A8H4V9P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ophiocordyceps sinensis|TrEMBL
MHIKDMLTEADKGHQPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGREKVNNALKMAYKAGCTNILALRGDPPRDQDK
WTATDDGFQYARDLVKHIRETYGNHFDIGVAGYPEGCDDNKDEDELLDHLKEKMDMGASF
IVTQMFYDADNFIRWVAKVRDRGITAPILPGIMPIATYASFVRRANHMQCKVPKHWMDAL
EPVKNDDVAVREIGKTLVADMCRKLLANGISHLHFYTMNLAQATRMVLEELSWAPCAERP
LHHALPWKQSKGLGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPATVRDLANTFVRYLDQEIDSLPWSESPLTGESDMIKQNLVA
LNKRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPPETVGAIISRIDNRP
SLTYYAITKDGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
AHCFESNTPTRALLDKVMSEWYLVNIVNNDFHDNAAIFELLKDVEVEELDATQAA
>A0A813CKP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symbiodinium sp. KB8|TrEMBL
MHALGPLFSDFASGPSSTPERALQLTSKAKNHFGVLAGMHLNCTNKSSEMTGNALLKCKQ
RGVHGHPLGTAGGFSSALDLLKFIRQNHDDYFSVSVVDSDAKFMVRFSDVGKTVLAMIYA
GRPMRCLGRLLAHPRLRGGLMGQRRVAFRVLVRSLLVPAPPPPAPPAPAPPPPPPSHSLP
PFYRAPPSTSASSLARDPGGPPGSRGSILAAMVIDRLKPPKPSTLNLKIYRLDLTPDLEP
>A0A7R6Y5W0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. 131-2-5|TrEMBL
MSARQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGISG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A533VYH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thaumarchaeota archaeon|TrEMBL
MCCTGRDGRVTKLRQKLERSGFLRIVEVFPPSFTAERDREPLIGLRQKTRDFLERVKKIQ
NLADVILVADVKDLTRLKLGTVYAASMVQEEVGIEAVPVITARDSNRPAIRSAVLTALSL
GLDSLMFVWGDTYSEDNGAKNVYDYTGVGEMMREAGALFDRAGVRPTFFAPLDLATLDTP
RGRRLAHSRLKSGAEYLLAQPPTADVVHTFPSHMRTLRRRRLDSRVLLNVFPFRSLDDIE
YCRKKFGWDVPHHLDAIAEKGGEPELLREAKRVVDRLRTVGSQGVYVSTRGRPELARFIL
D
>L8H1T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acanthamoeba castellanii str. Neff|TrEMBL
MKIIDKINAAIEEKRTMFSFEYFPPKTDEGVINLFERLDRMASFEPEWIDVTWGAGGSTA
QKTLEICATAQKYCGLETMMHLTCTNMPRAEIDDALRQAKAAGIQNILALRGDPPRGEEW
KKVEGGFAHAADLVRYIRAEYGDFFGICVAGYPEMHLDSESRDKDLEHLKAKIDAGADFI
ITQLFYDTSLFLKFVNDCRALGINCPIIPGMMPIQTYGGFRRMTSLCKTFIPEHINKALE
PIQDDDSAVKKYGVDLCVQMCRDLLAAGTPGVHFYTLNLEKAVTQILEDLDLIAASRPSR
ALPWRSSAYTNRKEKEDVRPIFWANRPRSYMSRTASWDDFPNGRWGDSRSPAFGELKDWH
LGSMAPPRSNYSKQWGVAPEKVEDIINVFVGHCEGKVTRLPWVDTAIAAETSVIQQQLMK
INRAGFLTINSQPRVNAADSSDKLFGWGGPGGYVYQKEYLEFFCSPENKDKLLAQMVNFP
TLSYHVVNVKGESVANTKGTAAVTWGVFPGKPTVVDAAAFLVWKDEAFTLWETQWGNAYE
EGSVSRELIKEIHDTYFLVNIVDNNFISGNLFDIFDKVIDASTPSVV
>A0A226WZA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia sordidicola|TrEMBL
MKPIELSFEFFPPKTPEGIEKLRATGAQLKALNPKFVSVTFGAGGSTQQGTLDTVVEMMK
QGLEAAPHLSCIGSSKESLRAILGAYREHGIRHIVALRGDLPSGMGEVGELRYASELVGF
IRAEHGDWFNIEVAAYPEYHPQARSPKSDMDNFVRKVQAGANSAITQYFFNADAYFRFVD
DARKLGVDIPIVPGIMPITNFSQLMRFSEMCGAEVPKWIARRLESFGDDKEAIRAFGLDV
VTGLCERLTKEGAPGLHFYTLNGAAASKTICERLALPEA
>A0A2X4ZCV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella oxytoca|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAKDYWDSGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMFE
GLDNDPETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A157SAG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella ansorpii|TrEMBL
MNDHTIPAFSLEFFPPRDLAAQERLVRAAKQMLAIQPRYVSVTFGAGGSTRAGTADTVRT
LRNLGCDAAPHLSCVGASRDQLREILQAYRDEGVRRVVALRGDLPSGMGGDAGELRYARD
LVEFIRAETGDWFHIEVAAYPEMHPQSGSVKADMQHFVDKVNAGADAAITQYFFNADSYF
DFVDRAQEKGVTIPIVPGIMPITNHSQLLRFSEMCGAEVPRWIRLRLAEYGDDKASIRAF
GIEVVTRLCETLLDGGAPGLHFYTLNSAEAPMGIWKALGR
>A0A2I8QBP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium ENNIH1|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRAIAKDYWDNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCASTGIDVEIIPGILPVTNFKQAKKFADMTNVRIPAWMSQMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A1J5DVB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium CG2_30_51_40|TrEMBL
MPLKEKIEAGGFAVLAELEPPKGADFHSLLANADLVKGRVDAFMVPEMANSVVKASSLGG
CAFLQNRGFETVLQVCCRDRNRLALQADILAAGAIGIKTVMVVQGDDITFGDHHQARAVN
DVTLMQLLEAIAGLKNGKDMAGIELKGAPDFFVGSTFNAGAAGGALDLEIEELKKKKGLG
AAFVVTTPVFDTDIFEKLLVKLKPVGVSVIPTVLLLKSAGMARYIDRNVKNIFIPSQLIE
SIQKAPDKPVECVSIAGKLISRFKEMGAPGVLVSTIGWEEKLPQVLDEARL
>A0A2N1TAI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetae bacterium HGW-Spirochaetae-1|TrEMBL
MRLNTLYNNKFAVSFEIFPPKTAEGEKNLWKELDILSSHKPDFVSVTYGAGGTTRVKTLE
IALKVRDKYGIPPLVHFTCVGAGKNEIEAYLQEVKSHGIENILALRGDPPVGESRFTPHP
DGFSHASELIDFIKSINGFTIAAAGYPEGHLEAPDLDTDIDNLKKKVDAGAQFIITQLFY
NNDAFYDFMDSVEKKGIGVPIIPGIMPVTSLAQIQKITGLCGASVPDRLLGILKSCGSKD
SICEAGLDYSIEQCHELKTWGVPGFHIYTINKSMAVTRIMDALGL
>A0A371PX05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces inhibens|TrEMBL
MALGTASTRTDRARTVRELLASGKQSYSFEFAAPRTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSTADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVKHPDGVAYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFVD
KCRAGADFAITQMFFYPEDYFRLRERVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATDLCARLMAEDVPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A157SSX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bordetella ansorpii|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTLLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A8H9XBA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp|TrEMBL
MDRDLRTALQRAIEAGDQVLTAEVMPPRGADPTHMLAMAASLQGRVHAVNVTDGSRAVMR
MSSLASCKLLLEAGLEPVLQMACRDRNRIALQSDLLGAHALGIRNLLCLTGDPVRAGDQA
DARPVNEFESVKLLQQVEALNRGVDPVQGTLPDGATTLFAGCAADPQSRSWSGLQRRLQR
KQAAGARFVQTQMVMDPEALERFQRELAGPLGLPVLAGVFLLKSAKNARFINRVVPGACI
PDALIHRLECAENPAMEGVAIAAEQVKRYLGIVRGVHLMAIKAEERIPMILDLAGLSSLP
G
>A0A7Y8N634|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. RM|TrEMBL
MTRTNTAGRDGDIRLSFEFFPPKNPDMEAQLWETVAELQTWDPDFVSVTYGAGGSTKAPT
LDAVRRMIGDSRLATAAHLTCVDASRDEVHQVIEEFTNAGVKHFVALRGDPSTGIGTAYT
PHPEGYENAAALVKGLREIGDFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQ
FFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPSFLDDRFAGYD
QDPEGRARVAGEVAAEQIADLQKRGIHEFHLYTMNRAPLVNAVLENLGMQRLRRSAA
>A0A2S4T2B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ACNIH4|TrEMBL
MSQLASHFKHNQFCILLEYLSSAKGIAVPMSLAEFPCAITLADRVHADSDLPPLECAKTF
PSSVEKIIHYSGKGRDITDFETFLKLTQASGQKNLLLLTGDKLKGHTNGQDGTNRTRYLE
SVNAVMAAKCYGGFHIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIVTQLGYDMEALK
QAKAFLNRHRYPQNILACVMPLSLARANFMVKHNVAGIVITPHMLRALAQEEQDGRTENA
YKRCAIQILMCKYLGFAGVHLSACHKPEEQKLLEKYIEQYRHYGLQELEALWNALWQVKT
KNELVPELAYYSRQPSSSQLIKYQQLHFMHKALFESKIAKGVGHFIFKASLWENTPAAKA
LLKTEFISKQGVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDLCEFGDRECIH
SVKARLAKAVGQTDVLKEKLIPTVPIEVRGTSSWKNWYLATEA
>A0A4S1CJZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geomonas terrae|TrEMBL
MRESFLERIAAGVLVGDGAIGTMLYAKGVAPEANFEHLNLVRPELVLELHREYLDAGAQV
IETNTFGANCAKLSAIGLGAKVAEINRKGALLAKSAAAGRDVFVAGSIGPLGRGKAELSA
EQIAECFRVQSSALAEGGVDLLILETFSELDELLAALAAAKETGLPVVANLAFGEGGRLP
GGTRAEDAAQRLAAAGADLVGANCGAGPLELLATVKRIAAACSLPIAAYPNSGFPEYLEG
RYIYRTTPEYFADRAEELVEAGASLVGGCCGTTPEHIRVMAERLQGSTLSPKERVPAGLV
SAVPRSEDVAVGEALTPGPSPTGRGELSGSFLDAWGVEPVITVELDPPKGLDCERVLAGS
RALKAAGAHAINLAENPLARVRMGNLALAATIRREVGIEVIAHVTCRDRNLIGMQSDLMG
ASLLGVTSILAVTGDPASLGDEAGASSVFDLNSFTLLKLLSDLNRGVNALGNPIGAGTGF
TLGAAFNPNTQRMDVQVGRLEKKVANGARFVQTQPIYDIARFEEMMERTAGLSIPILPGV
LPLVSGRNAEFLHNEVPGIVIPEEIRKRMAGKTGEDGVAEGLAIAREFIEAAGARAGGFY
LIPPFGKYEIAVELVRFIKEKTRKAAFNLF
>A0A838VP78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostocaceae cyanobacterium|TrEMBL
AKSVFDLESVRLLQMIQKLNQGMDCNGTILADGATDLFVGAAIDPQSNSWSGLQSRFERK
VNAGAQFFQSQLITDFERLEKFMVKIAAGCDKPVLAGIFLLKSAKNAQFINRAVPGVNIP
EHIIERLDKAQDPLEEGIKIAAEQVQMAKQLCQGVHMMAVKREDLIAPILDLAGVAAIN
>A0A5C7R9Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiothrix sp|TrEMBL
MTSPILSFEFFPPKTPKMERTLWRNIGQLEMLKPAFFSVTYGALGSERDHSLDTVFNMQR
ECHVPVAAHLTAAGHTRESLLALAQRFKENGVQRIVALRGDADLTEGGLSDVADMVHLLR
TVADFDISVAAYPEVHPKAASLEADLKQLKRKLDAGSKRALTQYFFEPDMFLRFRDAAVK
MGIEQPLVPGILPVHDFDKVISFSARCGATVPAGLHKVFEGTVAGSQEQKKLGIELAVDL
CEKLMNEGVNQLHFYTLNIPSLTFEVAHQLGLPLAWDEQPYFKMAA
>U4UMV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dendroctonus ponderosae|TrEMBL
MEHQQNERTEFIKALLQETAEARWSLEISPSSELGCEVFQQLSPLFVAVTWLGNMNLEKP
ISDIAGIALAKKITQCNFPVLFHLCGRNIARRKMMEILDYLKRCKVRNLLALQGDWAHVL
ETDDTKCDFPYASDLVLFIKTHYPDDFSVGVAGYPDCHPHSRSLEEDLKYLKLKVSNGAD
FIITQVSFDYDCLEAFADNCKKHDINVPIVPGFLIIKSYKSVMDMQAHCNLKVPGKILSD
LQMYKSDVKAIEKYLVDLIADLIAKCKKNSSVFAGVHIFSMNDIVQVQKVLSKTKV
>A0A8E6RXS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 6,7:m,t:-|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A8I0AY34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp|TrEMBL
MAIDDRNGKTAERLRYSFEFFPPKSEDMADQLWKTVDELADWAPDFVSVTYGAGGTTREP
TLSTVRRLIAETPLRTAAHLTCVGATKEEVHQVVEQFRAVGVKHFVALRGDPQGGMGTPY
QPHPGGYANAAELVAGLRELGDFEISVSAYPEKHPESPDEASDIDMLKRKVDNGACRALT
QFFFDNDIFERYLERVRAAGISIPIVPGIMPIQNLTQLKRFASMCGASIPAFLDERFAGL
DDQPQARAAVAAEVAAEQIEDLVRRGVSDFHLYTMNRSALVTATLGNLGLRPLAARGREG
AGAAA
>A0A1Q8A6A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon 13_1_20CM_2_54_9|TrEMBL
MTKEDLSSLNGRVDAITIPALRNGNHDSSYPVTFNVSPQQRSLASAVLTRGAGIETVPTL
TCRDCREEDVVKVQGLLLKGLENILVLYGDPFSDRERDKYEFAKTADLIRRVVDSANGKR
PSIGATTNQYAQDTESEVLRALTKVEAGADFVITNMSFDSEKVLDHRDALLSAGLNVPLF
IQVSIPASLNNIVYVTQKFGIPLPAPVMRRLSADGLQVGVELAGEAFEKLEDEAEGIHFS
YLLRRKSPVTAYLRLLDRIGRRRTVLAAPVFDIPGQVLGS
>S3IFE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium grahamii CCGE 502|TrEMBL
MALNSDARRKIGISFEFFPPKSEEMEGQLWNAVNELQDWNPDFVSVTYGAGGTTKAPTLA
TVSRFLAETPLATASHLTCVGATKDETHSVIDSFRKVGVKHFVALRGDAPGGVGAPYQPH
PGGYANAAALVAGLREIGDFEISVSAYPEKHPESRDTAADIDMLKQKADNGATRALTQFF
FDNDNFERYLEKVRAAGVNIPIVPGIMPIQNLTQLKRFAGACGTVIPAFLDERFAGFDDK
PEERAKVAAEVAAEQIEDLARRGLTDFHLYTMNRSPLVSAVLTNLGFTREGARKAGAAA
>F4F1P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora maris (strain DSM 45365 / JCM 31040 / NBRC 109089 / NRRL B-24793 / AB-18-032)|TrEMBL
MALGLPSILPNPQPAIGELVRDRQPTFSFEFMPPKTEQGERQLWQAIRELEPLQPSFVSI
TYGAGGTTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRHVIGRLAGAGVRNVLAVR
GDPPGDPTGEWVRHPDGIDYAEDLVRLVRRSGDFSVGVAAFPYRHPRSPDIASDTEYFVR
KCRAGAEFAITQMFFDADEYLRLRDRVAAAGCDTPILAGVMPVIRIGTIERSVQLSGAPF
PPALAARFERVADDPEAVRRLGIEQASEMCQRLLDEGVPGIHFITFNRSTATREIWQNLR
VGAST
>A0A4U6BAB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. LC34|TrEMBL
MRSETARHDGDIRLSFEFFPPKNAEMETHLWETVAELKKWNPDFVSVTYGAGGSTKAPTL
DAVRRMIGDSHLPTAAHLTCVDASRDDVHQVVEEFRNAGVRHFVALRGDPSTGIGTAYRP
HPEGYENAAALVKGLREIGDFEVSVSAYPEKHPESASEAVDIDMLKRKADNGATRALTQF
FFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSVPGFLDERFEGYDD
DLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVNAVLENLGLERLRRSAA
>A0A2E8A5B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Opitutae bacterium|TrEMBL
MSNGISIRSRFKTGKPMFSVEFFPPKDEAGGKRMLQTAKVIEPYNPDFVSITYGAGGGTR
ETTMRFARLLKEEHGFEVMPHLTCVGHTRDELLEILEEFADLGFRNIMALRGDPPSGETS
FSPVMNGFSYASDLVELIRNNFPDFGIGVGGYPEKHPEAPDLDSDLKNLRTKVDAGADFV
TTQLFFDNQAYFDFVRNSRNAGITIPILPGLLPVLSMNQVKRFCKMCEASLPSDLEQALE
KSEEKSHPEVGSMWALQQVKELLDSGCPGFHLYALNKSQSTLTILDGLTQRLRN
>A0A381EDM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cardiobacterium valvarum|TrEMBL
MSVTRVPLSCEFFPTATPEGAEKLAAVRRDLAVFQFEYFSVTYGAGGSTRDRTMNLVARM
CAENGPPVMPHLTCVASTEAEIRTLLDDYRALGVNRLMALRGDMPSGAFENAGFTTATQL
VSYVRQLWGEDARICVAAYPEVHPRARTPAEDLHAFREKVMAGATDAVTQYFYNADAYLH
FRDDAQALGVEIALVPGIMPISNFVQLSRFSDACGAEIPRWLRKRLEALQDDIPALCDFG
ADIVAQMCERLIAEGVPALHFYSMNRADLIREICKRLGWC
>A0A5B9WIU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sp. XS-30|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPSYINVTYHRSEHMFKKR
ADGSFDKVEIRKRPGTVGICAAIMNHYNVDAVPHLICGGFSKEETENALIDLAFLGIDNV
LVLRGDAPKNETFFEPHPNGHRYAIDLLHQVAQMNNGIYLEEELMGGVKTKFCIGVAAYP
EKHFEAPNMATDMKYLQRKVEAGADYIVTQMFFDNQKFFDFVAKCREADIKIPIIPGLKP
LTTKKQLTILPRTFHVDMPDDLAIEAMKCKTDKEVEQVGTEWLIQQSKELKAAGMPVLHY
YTLGKPHVIRKVVESIK
>A0A2A4PL38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Piscirickettsiaceae bacterium|TrEMBL
MALEXHQPISFEFFPPKTEEGRVKLLXVSKKLGQLDPAYFSVTFGAGGSTQQGTIDTVLD
IKKQGFXAAPHLSCVGSTKENIRAILANYKEXGVDRIVALRGDIPSGTLDXGEFRYANEL
VXFIRXETGDHFHIEVAAYPEIHPQAKNAQTDLKNFKQKVDAGANGAITQYFFNFEAYIR
FVEDCDKMGINVPIVPGIMPITNYSQLARFSDMCGAEIPRWIAKRLEGFGDDRESIKAFG
ADVVSELCQSLLDYGCPGLHFYSMNQAEASLVICRNLGVENA
>A0A829RAR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria grayi FSL F6-1183|TrEMBL
MNLRRDLNEKVLIADGAMGTLLYSYGIDRSFEELNLSHPDDVSGIHRAYIEAGADIIQTN
TYGANYIKLSRYGLEDEVKKINQAAIRLAKEAARGTGTYILGTMGGINGSSDTKLPLASE
EEVKRSFREQLYCFLLEGVDGLLLETFYDVDELKTVLKIVRETTDLPVIANVSMHEPGLL
QNGQQLPEVLKELEALGADCVGMNCRLGPYHMARALETVPILQKSHLAVYPNASLPEVRG
GKVVYHTETEYFQNYGEIFRQEGARIIGGCCGTTPEHIRALREGLKSFEPVTSKKVRPII
ELVPAEKLEDDGEERLLDKVKREHTILVELDPPRTFDTDKFFEGAEALHENGVDAITISD
NSLASPRISNMALASILKHQYGIKPLVHLTTRDHNLVGMHSHIMGFHKLGLHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKYNAGISYTGKSLKEKGRFHVAAAFNPNVLNVEK
AVKLIQRKVEYGADYIITQPVYDKEKIAILKDALQKADIKVPLFIGVMPLLSGRNAEFLH
NEVPGIRLPNEVRERMREAEAADRSKEEGMKIAKEIIDSIYTEFNGIYIITPFLRYDLSV
ELATYIQNKKRDPCAWKIAGSLFFNSINCVTIILIKIQRQASRRKS
>A0A2E5N059|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetovibrio sp|TrEMBL
MGQALEKPIEKELKSGSNLERVLASGHFAVTGELGPPRSMNLDLINRKITYLKGFVDAAN
LTDNQTGIVRLSSIATSILCHQGGLEPVMQMTCRDRNRLAMQSDLLGANIHGVKNVLCLS
GDHQSFGDHPGTKNVHDIDSMQLIRMVSEMRDKNQFQNGVEIKGGGPKMFIGAAASPFSS
PVEMRPLRLAKKVLAGADFTQTQMIFDMEKFKIYMRRIVDMGLHEKISILAGVGPLKSAP
MARFLHEKIPGIEVPEHLIERMENAVKDIDKEDKEARQEAGRAEGIKICIEQIEKAKEIE
GVAGVHIMAIEWEAAIESIVKGAGLFPRPVI
>A0A506QD00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAITNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLKQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7Z7W0N6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus schleiferi|TrEMBL
MSQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A6N9Z7N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium aerophilum|TrEMBL
MHSPMFSLEVFPPKRDAPIGTIYDALDGLEGLRPDFISVTYGHGTHADRTATARIANTIR
KDYQIPTVAHLTALYSDEAKIDDALDLFTQAKVSGVLALRGDHLDGLEPSGVFAHASDLI
AYIRERKPDLKIYAACYPEGHIESESLDDDIAHLKTKVDAGASHLISQLFYDNADFYRFL
DKARAAGIDVPIEAGIMPVTSAKSVLSMAAKNNTRIPKAVSAMLDKWGDDLPSLRAAGIN
FAAQQITNLVANDVEGIHLYTMNRPGTARHIWHNVSTLFSE
>B7IXP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus (strain G9842)|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKHAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2D8YVX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetovibrio sp|TrEMBL
MPKPPTDNLRQVAAFGRAAVAGGSVAAPLPDDVEVSFEFFPPSSDGAEANLWNSIQRLAP
LNPKYVSVTYGAGGSTRERTHATVKRLLDETNLLPAAHLTCVDATTQEIDAVAQDYWDMG
VRHIVALRGDPQDSSGRYTPHSGGYSFACDLVAGLRQIGDFNISVGAYPEVHPEARSAKA
DMDNLKRKIDAGADQAITQYFFDTDVYLRFVDQARAAGIWVPIIPGIMPIHNFTKVANFS
KRCGATIPRWLGDLFDGLENDPETHKLVAASLVAEQCRTLHAFGDKQFHFYTLNQADLTY
AICHMLGVRPKHPVGSDADDRTNKKQTG
>B4L1B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila mojavensis|TrEMBL
MSRSRNAALLPPLLRNVTPFAVQNRVYRHNKRNQLTERTDRVSMHSLEANAMRSFAGDAS
QGLIEPCFRYTPEQVANAGEQPYVSDVVLSKVERREFFYGIEITAQSNGKLTCVDFNSFL
PILPSFISIVWLPHYWNVTPLERVETLQMIRHLEPYIPAMPHFSVYKQTKKRINEFLSLN
FKNLLAVRGDKRDDNQFYLYGYQLIEHARRVRKEHISIAVPGYPQGHVSLDKGKIDMDQN
IAFLKIKVDKGADFIITQMCYSAELIIKYVQAARDAGIVTPIMVGVVVPESLQAYKLMEK
ITKIKLPRKKLAELKKIEKDDAKVRKFFVHSALSTILKVLDAKLDVYGFQFYTMNRFGAV
HDVLRKLRKRGILKETPPDACEDA
>B9C039|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia multivorans CGD2|TrEMBL
MKPIELSFEFFPPKTADGVEKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
DGLDAAPHLSCIGSSRDSLRAILDQYRSCGIRHIVALRGDLPSGMGSVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DVRKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTGLCQRLIDAGVPGLHFYTLNAAAATKAICERLDV
>A0A179FDQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pochonia chlamydosporia 170|TrEMBL
MDKITDKIAALPADREYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSKRLIDKALDDAKALGIRNILALRGDPPRKEE
YRDASDPEDDGQEDFTWAIDLVQYIRKKHGDHFCIGVAAYPEGHSDESHPLGQSLEHDLP
YLVDKVQAGADFIMTQLFFDINAYDHFEKTLREHPSGAFKTIPILPGLMPIQSYQMIKRT
TKLSHAKMPTAIMDRLDAVKGDDEKVKLVGVDVISELIDQIRTIKNRTPGRRGFHFYTLN
LEKAVSFIVERTGLIPDESENDEAVIDDGALSPPAIQVNGTRTSTHSRTSRRHSSVGSDP
HNRVIVGGRPATHPEWEATGQEAGVPAESINSRANTLAISEGEGVLGREATWDDFPNGRF
GDSRSPAYGEIDGYGVSLHMSVTQAVTLWGRPTTREDVNNVFVKHIKGEVPSIPWSEEGL
SPESSTIQSRLMDMNTKGWLTVASQPAVNGLSSSDRTFGWGPRNGFVFQKAFAEFFLPSA
DWALLADKLKGSDYCDSVCFYAANAKGEFVSSDVTGGVSTRTVAASTNAVTWGVFPGKEI
VTPTIIEEVSFRAWSEEAFGLWGEWAKVYGRGSESEKLLSGIRSDYWLVNIIHHDFIDRE
ALWKLLLG
>A0A077EIR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elizabethkingia anophelis NUHP1|TrEMBL
MKVTEHIAQSKGKTLLSYEIIPPQKGHGIGDLYKNIDPLMEFKPSFIDVTTSREEYIYLE
KGNGLMERKISRMRPGTLGICASIQYKYNVDTVPHVLCGGFTKEETEYLLVDCLYLGIDN
IMALRGDAMKGEKYFEPTKGGNRYASELVTQINDLGKGKFLHGEISGNDTNNSFCIGVAG
YPEKHLEAPSMQYDLKMLKQKVELGADYVVTQMFLDNQKYFEFVKLAREAGIDVPIIPGI
KPFAVKKHLQLLPQVFKIDIPEDLVNAVSQCKNNEAVKQVGIEWCVQQCKELLDFGVPAL
HFYTMGKSDNIQKIVSEFF
>A0A4R8UNK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Hz9|TrEMBL
MTEIGISACNVRPAFSFEVYPPKSTVAAAALTRTIDHLAAAGPEFISVTYGANGSSRRSS
LDVLRYIKDHTTVDAMAHLTCVGSSHAEASRLIREFLDAGIRSFLAVRGDAPQGAVEGDS
TFLGDLHSAGELVQLIHRVQTERVPYTETVIPGLPGARGVKTERSKVRIGVAAFPNGHPS
SRSVSQDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLFPILPGIMPVTSPN
RLRRIVQLSGEKLPAELSIELEVEPTEEGQRQIGVDYAVRLGRDVLAGGAPGLHLYAFNQ
HDTVLKVLEGCGALAVPVAMP
>A0A4Z0K518|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium sp. S22|TrEMBL
MSQSTLRRLLSTARYEVLPTAGIVERIEEYVAPGREITVTASTGLTLEATLSTAEQLQAL
GFRAVPHLAARMIHGRPELTEIVDRLAEAAVDRVFVPAGDATPPAGGYVGAHDLLVDLSS
MAAPFRHIGVSAYPESHPIIPDDVTVQAMWDKRDYATHLVSNLCFDPTIVASWVARVRSR
GIELPLVLGISGKVELAKLARVATKIGVGESTRFLRKNTTTFTRMAKPGGYNPRKFLDKI
TPVLDDPAMGVAGLHIYTFNQIKDTELWRRKQLAALGGAEEVTTAW
>A0A443IGQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Pantoea] beijingensis|TrEMBL
MSFFHANQREALNQNLAELNGKINVSFEFFPPRTSEMEQTLWSSITRLSSLKPKFVSVTY
GANSGERDRTHSIIKDIKERTGLDAAPHLTCIDASRDELRGIAKDYWNNGIRHIVALRGD
LPPGGGKPEMYGVDLVALLREVGEFDISVAAYPEVHPEAKTAQSDLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSIGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMSAMFE
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPDTVPHV
A
>A0A098BYC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fermentimonas caenicola|TrEMBL
MNIPELIGKGGKTAFSFELLPPLKGNSIQQVYRTIDRLIEFDPKYINITTHHSENIYKED
SNGVYRKVNVRKRPGSVAIAAAIQNRYGVTAIPHIISQGFTKEETEYALIDLSFLGVTNL
LLLRGDTKKLDADQRAMDSHKNATGLQEQVNNFNKGISFDGSPLAPPEVPFSYGMACYPE
KHEESPNMESEIFFTKMKVDNGAEYLATQMFFDNRKYFEFVDRCRAAGITVPIIPGIKPI
NLMSQLTVLPRIFRTDIPEELEKELRKCKSDDDAKEVGVEWCIKQCKELIAANVPSIHFY
SLMATESIYRVAKEIY
>A0A177IME8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium stationis|TrEMBL
MVPRMSASAPLDYLELDPAGHPRVENKEQAFSRTALSFEVIPPRHDADQAKIANLLQVLG
SYNPDYIAVTSSKRSGWLEGTAKFIEQISSTTTMRPLAHLACTAGDKRELISWINVLVDA
GVRGFLALRGDLEPGQTSLPEGYLQHGDELVRLIRQLEGEQAARFAAGRLAVAVACYPNG
HAESANDDEDFDVLLSKQRSGADLAITQLFFDAEDYLKFSQRAQLAGTKMPLIPGIMPIT
SLKRAQRMGELSGLKVPPKLIDKLSRARSPDEEYAIGMAHTVELAQAVIAAGAGCLHIYT
HNNADITQELLTAIGITANSTIKS
>A0A1F3KCG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWF2_35_48|TrEMBL
MKIVDLLNASEKTRFSFELLPPLKGNDINTIYMTIDPLLEFNPAYINITYHQEEIIYKKH
SSGLLEKKTVRKRPGTVAISAAIKYRFKDVLVVPHIICGGFTKEETENALIDLEFLGINN
ILVVRGDPEKSQKVFTPEPDGHKHSVDLLKQIISMNQGKYLDEELLNSTPTDFSVGVAGY
PEKHCEAPNMNTDLFFLKQKINAGAEFIVTQMFFDNKKYFDFVAKCREIGINVPIIPGIK
PLSVRSQISALPFTFHIDVPEDLVKEVIKCKDNEAVRQVGVEWTIAQSKELIKSGAPAVH
YFTMGKPDNIQKIAKEVF
>A0A6A2XN24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hibiscus syriacus|TrEMBL
MESYDATRMVFYRIQSLDPENASKIMGYLLIQGHGEKEMVRLAFGPEALIHSLILKAKTH
LGLSISSPPTPSTPSSPLPFSSRPSPLSIPSNVSNGFESPSLSYASLVNGSSTGNISSSC
NEFVDEYHQFQDRLSFLNDSKPEDLLFDPRLDLASMASPTGGYADSLLHRRSFSVPGLCL
GAEDLNSGLGLKPCLYFARGFCKNGSSCRFIHGDHCAESATNMTELERCQELLRSKSLQQ
QQQKLTATSSPFLPGGASFPYNKCVNFLLQQQQNETHRSAAAGLMMGDELPKFGRSKLPE
AEAVMVAEVVSKLVLISCSVKVVVVAVKSSKEENMPSATAASAIVSAESIVQPTTVQKKR
WGSCWSFYWCFGSHKNSKRTGHAVLVPEPVAPGAAVSTAENLWRTKMQKRRSRRSPSPMV
SPAPEETQSPPHGQDKFVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEANPDAMGDN
GHQNDLVYLKRKVDAGADLIVTQLFYDEITAALEPIKDNDEAVQAYGIHLGTEMCGKILA
NGVKTLHLYTLNMEQDHILKANGGEEGRGNVSMLNQLMQYVQLQCSSKLPEAEAVMVAEV
VSKLVLISCSVKVVVVAVKSSTDSTFKEEDVSNYFSIYGPVQDVRIPYQQKRMFGFVTFV
YPETVKLILAKGNPHFVCNSCVLVKPYKEKGKVQEKKQQQLERGEYSACSSPTPVDSREP
FDPHLGTRMFYNTQEMLLQRKMEEQADLQQAIELQGRRLMNLQMLDFKNQHQSPFHHGLS
TGSPIPSPTVSRTPTNQARIFPSDVFDQETPEGNAGSLIGPVSKLTAVTDADKLHEEVNL
SCNHKNGNENETGDDLTFFTTSSIEADDKTGRPTASSNGIPSLANASGLNMASLKSCFLQ
LPRFSSGQGAIEM
>A0A7C4M5D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidilobales archaeon|TrEMBL
MWFMKSACPKRMLNGPCGGYHGNLCEDPELRCVWIEAFNRLREFGKEKELFRLKLDAMFR
IRDYNPPRKRLRDYIISTRDFFMIYEYLPRKDLSLGSLESDLKKIFEIYDGLDIVQNPGG
RPLADPLALASIAKKFYPEKKIGIQITGRDYDRDGIVSHVVASLSIGIDTIVATTGDLKF
YERRSYGVWDLDSVRMIYLIRLISDLGRDYAGRKVYSGNNKILVGASLNPYLNPIEPEIY
KIKMKLDAGAYFFVTQPIFSKDTLDKLFLSIKRILGLEPQDLDIVIGLSPILDERTLHFL
KERSNIEIPEKITRSLKESSKSKILENYISHIADLLSEIEDTLISKILYISTYGDLEAGL
FVAERLREIL
>A0A160SZB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Promineofilum breve|TrEMBL
MNRRQFRERLQHGPLLMDGAFGTVLHGRGVPIDQSFDAVNLSNPALVAEIHRAYIDAGAD
LIETNTFGANRYKLGENGQQDKVDEINRAAVHVARRVIDGSYKEIILAGSVGPLGARLAP
LGRVTFAEAQEAFHEQIQALHDAEPRGVDVIIIETMSDIKEIEAAVAAARAVSADLPIIA
QMTFTRDDKTILGYPPEAIATQLAKLDVDAVGINCSGGPAQVLRLISIVRKLAPEIPISA
SPNAGWPEQIQGGRVMYPATPDYFGDYARAFVEAGVNLIGGCCGTTDAHIRAMRRALDTP
GASHVSAPEIHITNRPETTVTVGDRPTRLAQYLAERRMILTVEMNPPKGVSVGRLLAGAR
MLREAGATCLNIADSPLARMRMSAWAAAYLVQKEIGLEAVLSFPTRGRNILRIQGDLLAA
HAMGIRNLFVTMGDPTRIGDFPEAMDSYDIVPTGLIELIKNQFNQGLDKAGQSIDQPTTF
VVGCALNLTPKDVAAELKLLRKKVEHGADFALTQPVFDPLAAIEFLQAYERTYNEPPPPI
VAGIKPLYNSRNAEFLHNEVPGMHIPDVQRERMRQAEKPQAEGVAIAREIATALRPYVGG
FYIMPAFGHYDLAADVLDGFREG
>A0A7S9C4F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kinneretia sp. DAIF2|TrEMBL
MSTPPVSFEFFPPNTPVGTEKLKTVVQELGTLKPQYFSVTYGAGGATRDKTLATVMGIAA
TGFEAAPHLSCVGSTRESIAEILATYRAQNIRRIVALRGDLPSGTATAGEFRYAAELVRF
IRETQGPDWKIEVAAYPEYHPQQRYAAKDLQHFADKMRAGATAAITQFFFNPDAYFHFVD
AARKLGVEAPIIPGIMPFHNYGRIAQFAARDGIEIPRWVALKMEGYMDDSASIRAFGLDV
ITQLCERLIAGGVPAIHFYTLNQSALTLELCKRLKLG
>A0A7U5WDZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. YAU14A_MKIMI4_1|TrEMBL
MTAISFEFYPPKTDEQRGQLDRAAARLKAYAPDYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIAFI
RAEHGDAFHIEVGAYPETHPQASDALADLRHFKAKIDAGADAAITQYFFNADAYFHFVDA
VRKLGVTVPIVPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGAEVV
AGLCQRLVDGGAPGLHFYTLNLAKPTVSVLKLLQG
>A0A6A3D5Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hibiscus syriacus|TrEMBL
MLKMKVIEKIQSSPQNQGKVVFSFEFFPPKTEDGVENLFEMMDRMVAHNLSFCDITWGTS
GSTVDFTLYIVNKVQNIICVETMMHLTCTNMSVKKLDHALEIIKAKYGDYSGITVAGYPE
AHLDAIGDNGVATPEAYQNDLAYLKRKVDVGADLIVTQLFYDEITVALEPIKDNDEAVKA
FEIHLGIEMCRKILANGIKTLHLYTLNMKQDHILKANGMVNC
>A0A7U0ANC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Morganella morganii|TrEMBL
MSFLHIDQHEALNQNLAELAGRVAVSFEFFPPGTPEMEKTLWQSIERLSVLKPKFVSVTY
GANSGERDRTHSVIKSIKEKTGLIAVPHLTCIDATRDELKTIAGDYWDNGIRHIVALRGD
LPDSSSKPDMYAADLVGLLKSVADFDISVAAYPEVHPEARSAQSDLINLKKKIDAGADRA
ITQFFFDVSTYLRFRDRCAAAGIDVEIVPGILPVSNFRQLQRFAGMTNVRIPGWLGTMFE
GLDDDSESRKLVGASVAMEMVKLLSREGVKDFHFYTLNRAELTYAICHTLGVRPAACVA
>A0A410SH73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parainfluenzae|TrEMBL
MSYAKEIDTLNQHLADINKKINVSFEFFPAKNEKMESMLWDSIHRLKELNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGLEAAPHLTGIDATPEELKEIAKDYWDSGIRRIVALRGDEP
KGYEKKSFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDNYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMASFTNVKIPAWLTKAYEGL
DDDPTTRNLVAASIAMEMVKILSREGVNDFHFYTLNRSELTYAICHTLGIRPKSN
>F4MU24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia enterocolitica W22703|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASPTQLREIATDYWNSGIRHIVALRGD
LPPDSGKPEIYASDLVGLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A448Q7T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parainfluenzae|TrEMBL
MSYAKEIDTLNQHLADINKKINVSFEFFPAKNEKMESMLWDSIHRLKELNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGLEAAPHLTGIDATPEELKEIAKDYWDSGIRRIVALRGDEP
KGYEKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDNYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMASFTNVKIPAWLTKAYEGL
DDDPTTRNLVAASIAMEMVKILSREGINDFHFYTLNRSELTYAICHTLGIRPKSN
>W6V247|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. (strain GM41(2012))|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLIATARHLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLAQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLNNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>X5PGW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSJC277A00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTIKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A1R1K0N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVAKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAELGDDKASIRAF
GVDVVTELCQNLLDNGAPGLHFYTLNHAEAPLAVWKELSV
>A0A353HS69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp|TrEMBL
METHNFSIEFFPPKTPEGVEKLRVTRRKLAELNPTYFSVTFGAGGTTQQGTLDTVLDIMA
DGHMAAPHLSCIGATRDSIRAILRQFQQQGIRRLVALRGDLPSGYGGAGELRYANELVEF
IRQETGDWFHIEVAAYPEMHPQARSPQDDLQNFARKIGAGANAAITQYFYNADAYFQFVD
NVRKMGIEVPVVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLAGGAPGLHFYSMNQAAATTAIWQRLTGK
>A0A2E2XKI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellvibrionaceae bacterium|TrEMBL
MSKDNLRLSFEFFPPKSDDGKTKLVNVRNELQKLNPEFFSVTYGAGGSTRDNTKDIIKEF
KKDGISVAPHLSFGGDDEATMKALLQEYKDAGVDRIVALRGDMPSGMGGAFQMVYANQLV
AFIRENFGDHFHLEVAAYPEIHPEATSYDDDIRYLKGKFDAGADSALTQYFYSPDAYFYF
LDQCEKAGIENPIYPGIMPIINYKNLFRFSDNCGADIPRWLRRRLESFGDDNESVKAFGL
DLVTELCETLLENGAPGLHFYTMNQVEPTAAIVKNLGLDS
>A0A369ZIJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus parainfluenzae|TrEMBL
MSYANEINTLNQHLADTNKKINVSFEFFPPKNEKMESMLWDSIHRLKVLNPKFVSVTYGA
NSGERDRTHSIVKAIKAETGIEAAPHLTGIDATPEELKEIAKDYWDSGIRRIVALRGDEP
KGYAKKPFYAADLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIEAEIVPGILPVTNFKQLQKMASFTNVKIPAWLSKAYEGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHTLGIRPTTNP
>A0A6I3WRD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MAKIGDLLRIGRTFSFEFFPPRTDDAQLTLGRTIAELEPLRPAFVSVTYGAGGSTRARTR
DVVTWVRRETNITPMAHLTCQGHTRTEITEILDHYRDADVHNIMALGGDLPSDPADIRPS
DYTYASELVAEVNGYGYFSVGVAAHPEGHPRSPDRATDRRRLADKLRHADFAITQFFFEA
SHYVRLVDELMALGVDKPVLPGIMPVTNKGQIVRMAEMSGTALPSWLVERLNGTDDPHEI
RKIGVDVATTLCEDLLAAGAPGLHFYTLNRSTATREIYANLNLSSMH
>A0A2M7IRZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium CG_4_8_14_3_um_filter_37_9|TrEMBL
MKSFRERLGNELILFDGGTGTYLYEKGIYINRCFDELNLTNPELVTEVHCDYINAGADII
ETNTFGANSFKLTPHGLGNKVYEINLRGAKLAKTAAKESVLVAGAVGPLGVQIEPLGKLS
FDEAKDVFKEQIKGLLDGGVDLIVLETFALVKELIQAIRAVRELNADIPIVAQVTINESG
TLLSGAPLERFIEKLKDYPVDAVGLNCSVGPKAMLDALENLRSLTDIPISVQPNAGLPQN
ISGRNIYMTSPEYMAEYAKRFIQTGANIVGGCCGTNPTHIKAMRKAVQALQPVKKMDVKI
ADLQVEKPSEIKIYEKNEKSRLSNKLLKKEFVKLVELVSPKGVSPSREVDKARKLYHAGI
DAINIPDGPRASARMSALALAAIIQKEVGIETVLHIACRDRNVIGMQSDLLGAWALGLRN
ILAITGDPPKLGNYPDATAVFDVDAIGLTNIINRLNHGLDIASNPIGDPTGFCVGVGVNP
GAINLDEELKRLEWKIEAGAEFMITQPVFDIKLLEHFMKRIEKIKLPLICGIWPLVSFRN
AEFMNNEVPGASVPQKILQRMKKMTTKEEGFNEGVKIARETFDQVKTFADGVQISAPLGR
IEAIFDMIE
>A0A7W0SYN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MDRFSERLSSGPPIVGDGGMGTLVTSAVSRLRCPEEANLRAPESVLSLHLGFIRAGAELI
ETNTFGANRHKLRTQYLEDEVKAINEAAVKIARDAREVSGRDVFIAGSIGPLGEMGARRD
DRAALFTEQAELLEGRGVDLFLVETFYELDELETAITAVRSVSSLPIVALLTFDEDAHTL
GGVSAARAASALDDQDVAAIGANHGLGLQAALRALEQMSGSGKPLAALPNVGLASLAGQR
VIFPHTTPEYFADFAAHAQELGARIIGGCCGTTPTQIAAIRDAVDEGRRSSVPLVVRDRQ
LVVAATEPEGETLLQRKLRTREFVVSVEIDPPRGGQAQAMLALAGTLKESGHVDVVDVND
NPRARARMSGLIASATIERVAGIETIPHLTPRDSSIAGLESMLLGAHAEGIRNVLAVTGD
PPEAGDYPGSGGVYEVDSIGLSRIITQMNAGEDFNGREI
>A0A851X9M6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eolophus roseicapilla|TrEMBL
MVNETQHSCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTRDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A7Y4HXE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. 260|TrEMBL
MSYPLPPPPTYPALSYELFPPRTTSAEEGMWRTIRALEDTRPDFVSVTYGASGSNRDTAV
GLLKRLLDETSLKPLAHLTCVGNSRDYLVQLVYELISRGVRGILALRGDRPLDRSLPEGD
LQHASELVELIRQAERQLTAHLCAGRVAVGVAAYTTKHPESPSTEHDIEVLLAKQAAGAD
FAITQVYFAPEQYSQLLRRARRAGVEIPIIPGVIPFTSVRRLERLSELAGLQIDARLKDR
LVSAVDDAERRRIGVRATVDLAHAALNDGAPGIHIYTFNEHAAALDVLDRLDLSRPPAPG
LSQTA
>A0A7X8UL39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MGTYRDACRRGNFVISGEIGPPKGTNVETMLHHIDTLKDMVDGLNVTDNQSAVMRMGSLA
VSGEIVRRGGDPIFQTTCRDRNRLGLQSDLLSASFMGITNVLCLTGDHPVVGDHKQAKGV
FDFDSIHLIQCCHKMNEGIDWEGNELDGAADFFIGAVVTPEADPLEPQMYKFARKVEAGV
DFFQTQAVYDMDNFQRFMEEAREITAGTDTKIMAGLVVLTGLGMAKYMNRAVPGIFVPDA
LLEEMGSVPKEEQLHKGMEIAARHIRFLRDNAVCDGVHIMAIGKEEIVPEILEMAGAVDR
>A0A538BFH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTVERLTRTGDRRLRREGWDTARMDAAAFRSLLAEGPLLADGGMGTSLIARGIPVDACME
ELNVRAPTRVAEIHASFVGAGARLVLTNTFGANRYRLERHGLADRFAELCGAGVALARDA
GAPIVAGSMGPLGIRLQPYGRVHPEDAFAAYREQAAALADAGVDLLVVETQSDLRELEQG
VLAARDVAPDVALIASATFTRDDRTLLGSPPDEVAQAVVALGVDALGVNCGEGPAQVLRI
VRAMRRTAAGAGVPIVARPNAGGPAEVGGRFVYPATPEYFGEIAQALLDDGVAVVGGCCG
TGPAHTTAIGTALRDRAPHARIEFPEADHGERILDVVTVAPPTKLEAKLATGHFVVTVEM
EPPRSFNAARLVAAAETLRDAGADAIDVADSPMAKMRMSAWAACRLIHEQAEIETVLHFP
TRGRNLLRLQGDLLGAYALGIRNLFVCVGDPVTIGEYPHGSNNVDVTATGLLSMITHAFN
AGVDRSGTSIGAPTSFFAGAAVAPSAPDLEREARLLARKAEAGARFVLTQPFYSIDPLLA
LRETYEKIAGEPLTVPVVAGVLPLMTSRHAEFLHNEVPGIEIPEAARDRMRSAGDDDEKA
WGEGAAMAVELIAALREEEVAGIYLMPQFGRYDRAAEVVEAARGAATM
>A0A7W0SRK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVALRALLEGPLFELIPLRDALERADALPSGAATTVTASPTHGIESTIELCEGLIARGHP
ATPHLAAHMVRDRAHLAELLDRCTSAGIRDLFVVGGDTKDRGEIHDGLALLRLMDELGYG
FDAVGVAGYPEGHPSIPHEVLLSSLKEKQAYATYLTTQMSFDAIAISSWVARMRGTGVTL
PVHLGLPGAVDVRRLLRVAARIGVGGSIRYLRKNRQLLRLLLGRSFTPDRLLRSLETTFA
DPRADVRAIHLFTFNQIEGTVAWQRRILETLSS
>A0A2N1IR19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas monteilii|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFYLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A1I2ERN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptostreptococcus sp. D1|TrEMBL
MSFDEAYDIFKQQMVVGEESGADLIVIETMTDLYEVKAAILVAKENTSLPVFCTMTFEKN
KRTFTGCSLEAFAATVEGLGVDAFGINCSLGPDEIFPMAKILSEISSTPLIVKANAGLPN
LNTGKYDIDENDYAVWADKIAQLGVKYIGGCCGTTPSHIEKLSNNLKKHRIQSIKDEKPQ
VFKVRTKPSSNVFYDKLCGGKKVIAIELDPPADVDIEKYIKSLKSLKELDVDAVTIADCP
VGRARIDSSLMAYKIKNEVGLEPVVHLTCRDRNLNATKALLLGLNIENIRNLIVVTGDPI
PTAEKVE
>A0A6I2XPN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSDYLKTTTFSLEFFPPKDSIGEERLWQALSQLQPLKPDFVSVTYGAGGSTRDRTIRVTT
EITDRTSIPTVAHLTCVGSTKTELVEILNQYKSAGIKSIMALRGDPAGGPRAEWQNIEDG
FDHADQLVQLAASLGDFKIGVGAFPDGHPASGFNFDKDVDVLIRKEELGATFATTQFFFE
SSKWHKLVERLLKRGSKLPIIAGILPITNLKQLDRMVELSGTPIPAAVSKRFENSLNSPE
DIKKIGVEIATELGNELISLNAPGLHFYTMNSASSTISIAKNLGLVR
>A0A7K1ERP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MLSVGSKEEAKEAGIDWAANLVRELVEAGAPGVHLYAFNQHESVTQVLQRAGIR
>A0A7K0UP77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSADTAPTISFEFFPAKDEAAEANLWNAIADLQQYQPDFVSMTYGAGGGTRDRTVRIASE
FIARTGVPVIGHLTCVGSTRDELKEILEQYKSEGFHGVLALRGDPVGGPTAPWVTTPGGF
DFADQLVALAADVGGFSIG
>A0A7C2DBK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVSPPGEEHRVRHAAHRVHGARDRARGRHPEERAGAGGGGPDAALGPEEGDPQAVSQAAP
SGTVGRLLANARFEIVPTDGLEAELRHLAPGTTVTVTCSPRKGIDRTLEIAEHVQGRGFR
AVPHLSARLVTGRSHLRAILRRASDAGFRELFVVGGDATEPAGPYASAGELLREMAELDH
GVEAVGVAAYPERHPLIDEEELLRALLEKQPFAHHMVTQICFDPGALVRWLDEVRGRGVT
LPVYVGVPGAVRRRRLLEISLRVGIGDSVRYLTKHGGIVARLLRGGSYRPDGFLAGLAPL
VAGREDVLGLHLNTFNQVEATERWRREALRAYGYAPAAEAFPEEDAAS
>A0A7C2RM82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium|TrEMBL
MNLREKLAANKFVVTVELDPPKTLNIEKILREVNNADFRKVVDAVNVTDCPLAKLRMSPI
ALSHIIQDKIGLEAIFHITCRDRNLLGLQAELLGASALGVRNILALTGDPPEVGDYIMAT
GVFDVDSIGLVKMVNKLNHGYEYSGSKLKDNTDFFIGIAVNPTARNLTKEIERFEEKVSV
GANFIQSQPIYDIGLLESFLKLTAHINIPKIIGIMPLKSYEMVEYLSDNLSDIFIPPEVK
ERMRGKSIEEGVTISRELIDEISKFKDVAGIHIFPLRDMNLVCRLFD
>A0A7K0WWW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSIGRGRSLREVVEAGEKSFSFEFFPPKDEAGEAQLWDAVRALEPYRPTFVSVTYGAGGS
SRGTTVRVTRRIAQETSMLPMAHLTCVGHTRTELEAVLDEYAAAGVHHVMALRGDPEGGP
RADWTPTEGGLTYATELVELVAARGEFRIGVAAFPERHPSSPSLDHDADVLAAKARAGAE
FAVTQMFFRAEDYVSLVERVRARGVDLPILPGIMPILNLAAIRRQGELIGTDVPEEVVSR
IAAHEGDAVSMRAEGIALAAELCQDLLDAGAPGLHFYTLNRSKATLEIFEKLDVRP
>A0A7K0Q9F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MVVRTSYSLEFFPPKDSEGEARLWATLEALKPMAPEFVSVTYGAGGSTRNRTIGVTEEVT
HRSKIPTVAHLTCVGSSRQELISILHMYRAAGIRGILALRGDPPGGPRAAWTPTSDGFTH
ADELVQLIHEFGGFDIGVAAFPDGHPSSEGDSKKDLDVLLRKEFLGASFATTQFFFEVSK
WEQLVYSLEKRGSTMPIIPGILPITNVKQLERMAELGGTPIPPAVSSAFSTIGDDPDAVH
ALGIELATKLCEDLLSAGAPSLHFYTMNSATATKEIYGNLNHAH
>A0A538ANC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNGLELVTFLDRGPLLTDGGMGTALVERGVPVGACFEALNADDPAIVASVHRAFVEAGAA
MILSNTFGANRFALRRRGMADRSGELCARGVDIARAAGVLVAGSVGPLRVRLAPYGRVRP
AEAFDAFAEQIAALAGAGVDLVLIETQSDLAEIEQAVAAAREVCDLAVAVTITLTADDRT
FLDDSPEQVAERLVKLGPDAIGVNCGHGPAQALRVIRAMRPALGRVPLIARPNAGGPQQV
GGRFLYPATPDYFAENARLLLAEGVSVIGGCCGTGPAHVRAMARALREPRAPVVQVGPSP
TIEEAPDLASKGTELSAKLAEGRFVIAVELDPPRGFSTAGMLAGAETLAETGADVIDVAD
SPMARMRMSPWAACRLIQEQVGIETVLHFPTRGRNLLRLQGDLLAVHALGIRDLFVCLGD
PMEVGDYPGGTDTVDVAPTGLISLITGSFNRGRDHAGASIGEPTSFVVGCALNPAAPDLE
RECRVLRRKIDAGAAFALSQPVFSAEPLERVRAAFEARHGALTLPILAGLLPLASGRHAE
FLHNEVPGVSIPEEIRDRLRAAGASGERIGLELARELAHELRGAAAGVYLMPQFGRFDIA
AELVETLRRA
>A0A7J5WCB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSRLRDALERGEFVVTGEIAPPLGTDLAAMRQSIETIGPYCHAINITDNQGASLHLSSLA
ASRIALEMGYEPIFQQTCRDRNRLALQSDLLAAWTLGLENVLIVTGDDPRSGDHPQAKGV
FDLDSTQLLEVASAMNAGTDMLGRPLKGSTDFFMGAAMFPEAEPWDIQLLRAERKVEAGA
RFFQTQAIFDLAKLERTVAVMRPLGVKVIAGVIVLRSARAVDFINNRLAGLMVPDDIVAR
IKGASDVAIEAVALATEQVRAIRDIADGVHIMTLGLDSAVPQILGANQEA
>A0A2K3CB80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euhalothece sp. KZN 001|TrEMBL
MSRFRQAVEAQEFLVTAEVTPPKGGNPDRMLQVAQSLKGRVHAVNITDGSRAVLRMSSLA
ASVVLLRNDIEPVCQVACRDRNLIGIQSDLMGAQALGIRNILALTGDPVKAGDHPKAKAV
FNLESVRLLKLIQKLNEGTDFNDKPLTDGALDLFAGAAVDPQSDSWSGLQRRFEQKVKAG
AQFFQSQMLTDFDRLEKFMDEVASPVKKPILAGIFLFKSAKNARFIQKYVPGVHIPEEII
ERLDRANDPLQEGIKIAAEQVQTARQLCQGVHMMAVKKEEAIPEILDLAGVKPVEGVKLP
TAATR
>A0A5C7PEC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNLSERIAARGSELLLFALTPPRLSVTPEQARTIAAQTQQRLSPLGLDGLVLYDIDDESD
RNPQERPFPFLPTIDPATFLAEHLSAWGTPVIVYRAVGKYPEDALGSWLGAQDAAHTLTV
FVGAPSRHRRAATSLARAQEVWAQARPDLQLGGVAIPERHTRRGEEHLRLVAKQDAGCSF
FITQVVYDVNAAKNLVSDYRYECAARGAEPVPIIFTFSVCGSLKTLSFLEWLGVDVPRWI
QNDLRHAEDTLQASYEHALGAAREMIAYCRRSRIPFGVNVESVSSRRVEIEASVRLAQQL
GRELRR
>A0A543E7B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoxanthomonas sp. 3HH-4|TrEMBL
MPSISFEFYPPKTDEQRTQLDRTADKLKTHAPDYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGSREEIRELLRLYRALGCKRIVALRGDLPSGMGHPGDLRYASELIEFI
RAEHGDTFHIEVGAYPETHPQAADALMDLRHFKAKVDAGADGAITQYFYNPDAYFHFVDA
VRRLGVEIPIIPGIMPISNFTQLRRFSEACGAEIPRWIGKRMQALGDDADAVRDFGADVV
AGLCERLIAGGAPSLHFYTLNLAKPTQTVLARLGWTR
>A0A2E7T6D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSIFRGKEVPGDKVHRRALLERARFEVIPLKNLSSQLPFLPTDTEVSVTASPAKTLEDTW
SLSRELCQLGMKPVPHLAARMIKSRDQLRSLIEQLPDIGASEIFLVGGDAPDPFGPFTDS
IQALETILELDHGLTHIGVTAYPDGHSFIDSQVLSESLHKKEALLTLSGIEGHAATQMCF
DPNTIRSWLTDERSQGFGLPVHLGIPGAVERAKLLSVGARLGVGASLRFLKKNRATLTRM
FAPGGYDPDKLLRPLNSDLKALGVEGLHIFTFNQVQSTVVWRERAIARA
>A0A432CJW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium bomense|TrEMBL
MKVTQHIEAAKGETLFSFEIIPPQKGKSIQELYNNIDPLMEFKPPFIDVTTSREEFIYMD
KGNGLLEKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQSFVPKLGGNDFAVDLVKQINQLNCGKYLHDLMDVDDKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREIGITVPIIPGIK
PIAVQRHLQVLPQIFRIDLPEDLIHAVDQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A533RQA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MRRDVGREVRGPARPRVHARAHPRAPRRAGPLARGRRAAQGSQPQAEARSGEPARRRRGR
RPPVSRLRDALERGEFVVTGEVAPPRGTDLSAMLASVDILAPHCLALNVTDNQGAALHLS
SLAASRVLLDRGVEPIFQQTCRDRNRLALQSDLLAAWTLGLENVLMVTGDDPRGGDHPEA
KGVFDLDSTQLLTVASELNAGRDMMGRDLDGGTGFYLGGAIFPEAEPWEVQLDRAVEKAA
AGARFFQTQAVFDIAKLERAVSALRPHGVKVIAGVLLLRSPRVVDFINDKLAGLMVPEEV
GARIRGAADPKAEAIALAVEQVRAIREVADGVHVMPLGLDAAVPEILAGAGL
>A0A2G4FED2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSDLLSQGTSVSFEFFPPQTDEAEEVLSRTIGELESLHPSFVSVTYGAGGATRERTHDLV
VEINQKTSMTAMAHLTCAAHSRAELVDIVSRYRDAGVENILALGGDLPNDSDLSAGELEH
ALDLVRLIRATGDFSVGVAAHPEPHPRSPSLAQDRDRGAEKLGEADFAITQFFFETRHYF
DLVEDFRARGVTTPVIPGIMPVLSIAGTKRMTELQGSEFPQWFLDRLRLVEDDPAAVRAT
GIEEATRLCQELLDGGAPGLHFFTLNRSTATREIAANLGLPN
>U3GC79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ralstonia sp. 5_2_56FAA|TrEMBL
MQDRQFSFEFFPPKTAEGAEKLRNTRAQLSPLKPRFISVTFGAGGTTQQGTLDAVVEIQR
EGIEAAPHLSCVGSSRESIRGILNTYREHGIRRIVALRGDMPSGMGEIGEFRFANELVEF
IRQETGEAFHIEVAAYPEYHPQSRSARLDLENFARKVKAGADSAITQYFFNADAYFQFVD
DARKLGVDVPIVPGIMPITNSSQLMRFSEMCGAEVPRWIAKRLEGFGDDRESIRAFGLDV
VTAMCDRLLQGGAPGLHFYTLNAAGSTRAIWQRLGL
>A0A4R1DDI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. KM273126|TrEMBL
MALGTASTRTDRAPTVRDMLADGRTTYSFEFWAPKTAKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRSGTVKATEQIASDTTLTPVAHLTAVNHSKAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVPHPQGLTYAAELVGLIKESGDFCVGVAAFPEMHPRSADWDTDVSHFVD
KCRAGADYAITQMFFHPESYLRLRDRVAAAGCTTPVIPEVMPVTSVKMLERLPQLSNASF
PAALKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A3C0QIE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MEKEPKKLGFEKSLQQGKFTVTCEVGPPKGAEDEEIKEAVTFLKDIADGINVTDLQSSVM
RLGSLTTCNILKNMGLDPILQITCRDRNRLSIQSELLSAHVMGIRSVLALTGDHTTLGDH
PDAAPVFDIDSVQLLWAMKRLEEGFDLAGKELTAKPSFFKGAVVNPGADTEAAYEMQITK
LKKKIDQGAQFIQTQAIFDSEVFKKFMDRMEKEKITIPILAGIILLKSDRMANFMNKFVA
GVFVPEDVIDKMKNTDNKVETCKEIAVDLIEKVKPYCAGIHIQALGWEKHISPIIESVKQ
>A0A3B9VJ77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MNSAPTFSVEFFPPKDQAGEERLWSALKALEVYKPDFVSVTYGAGGSTRDRTIRITSEIT
ARSGLSTIAHLTCVGSSRDELIEILSQYKVSGIKSILALRGDPKGGPGVKWESTAGGFDY
ADQLVLLASSMGFEVGVAAFPDGHPASKGNFEQDIKVLLEKERCGASFATTQFFFDVKGY
INLVNQIRAKGSKLDIYPGILPITNFAQLKKMSELAGSAIPIEIQRRVEAAGDSPEEVVK
VGIDIASELSKDLLDYGVPGLHFYTMNSAAPTIEIIRRIGLR
>R7DNM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides intestinalis CAG:315|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYDTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNRYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELTCEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A537XTC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSETPGHLGRILRSGRFCVTAEVVPPRSADPAAVVAQAKELVGYADAVNVTDNPASAAHM
APLAGVAVVADAGIEPILQLTCRDRNRLALTADLLGGWALGARAVLCLSGDPAAQGDHPD
AKEVYDLTVLDLVGLAAGLRDEGRLLSGATIEGPPRYLIGVADLPLAAGYDPTRLEAKIS
AGADFVQTQIVYDVEAFTAWADGARSRGVFDRVAVIAGVAPLRNARQARLVASLPGVSVP
ADVLRALEEAGADAETEGTRLAILIVNGLREIPGLAGVHLMGLGQESAVRRVVEGAGLLP
RPVAAP
>A0A538CDJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MTIRSDSRMERLVHQGVFCVTSEVVPPRGADPSAVSTQARGLVGYADAVNVTDNPTASAH
MSVVAGSGLVAAAGLEPVTQVTCRDRNRLGLTSDLLGAWALGARNVLCLTGDPPTTGDHP
QTKGVYDLDVMELIGLAAGLRRDGKLLSGAQVESPPRFFIGVADVPLSPEYRFERLEQKA
DAGADFVQTQIVFDVDAFGEWADRARSRGIFERMFVLAGVAVARGPKTARYINQHLPGVV
VPPRLIQLLEAAGPDAEAEGIRLAVEVVAKLKAIQGIAGIHVMGLGQMGPVRRVIEAAGL
LPRPAAV
>W4SH99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. pruni MAFF 301420|TrEMBL
MIDPDTPSLASTITEAYSLEVSAKHIAGLAAAAPRIMRGATIAIPYLPNQDDDARLAAAR
MVRTLGFQPMPHLSARRIASREQLHAFVSRAVDDAGVERCLVIAGDPPAPLGPFPDSLSL
LDTGVFERSGIRTIAVAGHPEGHPSMPAADRWEVLQRKCRSIAERGMAPLIVTQFAFDAD
IVLRWLQALRAHGIAYPVRVGVPGPAGVAVLARYAASCGVSACASMLSKYGISLGKLLGT
AGPDRFVERLATGLTDAHGEVRMHFYPFGGIAQTVAWVEQYRSRSAHV
>A0A653XAE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. 8AT|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICSAIQHKYGVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTLGGHASAMDLVNQINNLGRGKYLHDDEQICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVKKAREMGITVPIIPGI
KPIATKKHLKLLPQVFKIDLPEDLINAVEGAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A5N1AM91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium amycolatum|TrEMBL
MPLSPGRQVTIRQALSMPSAGSIPFSVEFMPPRDDAAEERLLRAAEAFHDLGASFASVTY
GAGGSSRDRTLRIAQRVSRQPLTTLVHLTLVEHTVDELREILRSYLSAGLTNLLVLRGDP
PGDPLGPWVETEGGLHYASELIELIKAEPEFEKFEIGIASFPEGHYRSPDLDHDTQYTLA
KLRAGAEYSITQMFFDIEHYLRLRDRLVEADPVHGAKPIIPGLMPITSLRSVRRQVELSG
AQLPSDLEERLIKAADGDEQANKDEIRKIGIEFSTNMAERLIAEGVPGLHFMTMNFARAS
QEVLHNLGMAPEWGTGQDMLRGGF
>A0A259INU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. 39-46-10|TrEMBL
MELSVEFFPPKTPEGESKLHLVRERFSETLKPAFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVRDMLKQYQALGVKRIIALRGDLPSGMGQYGEFHHANELVEFIR
AETGDWFHIDVAAYPETHPQAKSPATDVDFFVQKMKAGANSAVTQYFYNSDAYFRFVDEA
YDLGVTEPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDTASIRAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLSLNK
>A0A0L8A6J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas geniculata N1|TrEMBL
LVALRGDLPSGMGFPGDMRYAAELIDFIRAEHGDAFHIEVGAYPETHPQASDALADLKHF
KAKIDAGADAAITQYFFNPDAYFHFVDEVRRLGVQVPITPGIMPIANFSQLRRFSEQCGA
EIPRWISRKMQAYGDDAESVRAFGTEVVARLCQRLIEGGAPGLHFYTLNLAKPTTSVLKL
LQG
>A0A1E3GQV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga muralis|TrEMBL
MSKQPVISCEFFPPKTEKGAQNLLLVQEQLSVLKPEFYSVTFGAGGSTQDNTLEAVVAIQ
QRAAETGIGAAPHLSCVGSSKERIRTILQTYIDNDISRVVALRGDLPSGMRDPGDFRYAN
ELVEFIRKETGDHFTIEVAAYPEVHPQAQDANSDFDNFKRKVDAGADSAITQYFYNIDAY
LYFADRCMQAGIEIPIIPGIMPINNYSQLARFSSGCGAEIPRWLRKKLEAYYDDIPSMQA
FTTDFLTDFTEQLIEIEVPGLHFYSMNKSEPVLTVCERLGLVR
>A0A2G4FIM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetia bacterium|TrEMBL
MSPIRTDPSLGAVLAGGGHSFSFELFPPKTDEGEQSLWQTVRELEALKPTFVSVTYGAGG
STQDRTVRITKQIAEHTTLLPVAHLTCVDASVDDLRKVIAQYSDAGVSTIMALRGDPIAG
PEAQWLRHPGGLQHADELVALVRSLGAFSVGVAAFPEGHPESGDFEDDARVLAAKQDAGA
EFAITQFFFRAEDYERLVTRAAAHGCTMPIVPGLMPVTNVAQIERFAVLSGAQFPSELAD
KFGKIKDDQSAVHELGVEVAADLGEKLLAMGAPGLHFYTLNRSTSTREVYKALGLNEV
>A0A4R1FUR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia alba|TrEMBL
MTTTDSRRPDCRETDGGPSHSVAQSLLTHVGGGAGVPFSVEFNPPRDAAGESRLWRAVRE
FERMHPAFVSMTYGAGGSTKDRTVRITGDLARETTLLPVAHLTAVGHSVAELRSLVGSYA
DSGIRNLLVLRGDPPGDPLGPWSRHPEGVDYAEELVRIVRDLGDFHVGVASFPQGHHRSP
DLDHDTRFLVAKLRAGAEYSITQMFFDVEHYLRLRDRVAALDPEQGAKPIIPELMPITSL
RTVARAEELCGRGLPEPVMARLRRAAGTGSQPDRAAVRAEGIAIATEMAQRLIVEGAPCL
HFITLNFAKATSEVLTDLGYGVGAAPLPGR
>F7NER8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetonema longum DSM 6540|TrEMBL
MTTKLSLKEALADPARPSITWELVPGRGVREKAQEHLVKMASLAAQDPRINAVTITDNPG
GKAAISVYAMAAEVKRLGIDPLVHFTTKDRNRNALESELYSLARADVENLLVMTGDYPVD
GYAGNAKPVFDFDAVHALRMITKMNAGSYTKLPATTFFAGAVVSPFKSTEAEAMAQYYKL
HKKAANGARFIITQLGYDARKFDELRKYVDLHQLSVPLIGNIFVLSLPVAKLMNKNLIPG
CVVTDSLVARLESEVGQENKKELQLLRAAKLYAVLKGLKYDGINIGGHGLGYSDVQYIID
KGEELSGNWQDIAKAEFDHPQENGFYFFEKDAATGLNTSQPVDRSKTGASGSFKQKFMDV
VHAVAFDRQAPFYPVNRAIARYIDQSWLKKPFTLAEYTTKTMTNQCRFCGDCAMHELGFI
CPMSQCPKQQRNGACGGSRDGWCEVYPGRQKCIYVTMYEGFKKGGKEERMKDKYMPPCNW
QLHRTSSWLNYFNERDYNSTKD
>C7MDX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / JCM 11609 / LMG 19847 / NBRC 14762 / NCIMB 9860 / 6-10)|TrEMBL
MPPRGAATQPAPEEERAAQFEVIPLRGIAEEVLAQLPAGARVTVTASPAQGLPATLEVTC
TLARHGFCAIPHLAARMLRDPGEVAEVLARLGEAGVREVFVIAGDAPHPAGRFEGALDLL
EVLSPSGMRAGIGAHPEGHPFLDEAAALSLLRAKAEHAAYAVTQMSFEAVPLLAWTRRLR
EEGITLPVRPGIAAPASTARLLRIGTRIGVGRSLRLLGADGSGMLRLLGPGQWDPGPLLA
QLASAAAEPGLALHGPHLYTFNAVRAAREAVTSW
>A0A6N6SZB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiaceae bacterium|TrEMBL
MRGAVPPAPNPELDHRLESTSSWLRVALGAPKARAPVHSPGASAAPVASDLQALLASGEF
AVTAEIAPPDTADPAEVSRQLEAFRGSVDALNVTDASGANCHMSSLAMSALLLQAGCEPV
MQITCRDRNRIAIQGDILGAAALGVRNVLCLTGDDVRNGDHPGARFVGDLDAVTLVAAAR
SMRDEGRFLSGRKILSPPQLFLGAADNPSAPPLQARLERLARKVAAGAQFVQTQYCFDLE
LMQRYMREVRAQDLHRRCHILVGVGPIASARAARWLRARVPGVMIPDRVIARLERALDPC
AEGRRICAEMIEGLRQIEGVAGVHIMAAKQEEAVAEIVAASAALGQRAPLFHCATPKPLN
PPSASECNTCP
>A0A2P1B644|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MSHVSPCFQQNQFFVLMEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEVSKS
YPESIDKVLHFSGKARDIQDFERFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVK
TGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEAMFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKKTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A841AG91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Conyzicola lurida|TrEMBL
MSVAPLTALQTPTFSFELYPPRSAAAEQTLLRSIEHLVAAGPEFISVTYGANGSSRNSSL
AVLLRLLEQTDVSAMAHLTCVGSSYADATRLIREFLDAGVTSFLALRGDPPAGAVEGDRF
LGDLGSAGELVQLIHRVQAERDQFSLNDIPGFPGAKRLSSGHKVTIAVAAFPNGHPRSRS
VEQDLDTLLAKEAAGANLAITQLFFHADDYLGFLDKARAAGVTMRILPGIMPVLSPQRLR
RIVQLTDETLPTDLLRRLEAERTPEGQAAVGIEHAIDLGSAVLEGTGGDSPGIHLYTFNQ
HEAVLDVLRGCRLLEPVTTEHN
>A0A8H3FCZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Heterodermia speciosa|TrEMBL
MEKITDKIAAVPKHGNYFSLEFFPPKTQMGFSNLQIRLERMSRAFRPLFVTVTWGAGGST
SSGSLQLAELCQSQLGLTTCLHLTCTNMKKKLIDHALEEAKGLGVRNILALRGDPPREEE
YRLPEEEDTEDDEESNEQFVWAIDLVRYIRRIHGDYFCIGVAAYPEGHADESHPVDQDPM
HDLPYLIEKTKAGADFIMTQLFYDEHAYVKFEKMLREHESGVFAKIPIIPGLMPIQSYQI
LKRTTKLSHCKLPQNLLDRLEGVRGDDEAVKRVGVDLLSEIVEDIKKIKSKGPRGFHFYT
LNLEKAVGFILEKCDLIPSDQSEDPNDSLAIDDFVLLSGTNDIQPADLHSTTSPVLMTSR
HRVDSTASQDQLTTYNSPHPPSSTSPPSRATNLAISHGLTPAGREATWDDYPNGRFGDPR
SPAFGTPLTYSPTSLPCPPHVARSLWGEPTSSGDITALFVSHLAGKPPHQLPWSESASLS
PETALIRAELHALNSDRSWWTIASQPAVDGIRSTDSIHGWGPPGGFVFQKAFVEFFCSAA
DFQTRVLPYLRSGAVAPQVSFYAGNAAGDFTSSEEADAVHAVTWGSFPGKEIITATMVEE
VSFRQWVEEAFGRWAEWARVVRTEESRRFLRKWKGDGWLVNVIGHGYRRGEERSLWELLM
GIGKG
>A0A8B3L958|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1A.F.Ca.IN.020.04.1.1|TrEMBL
MSIRHQRDENPAGVHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRA
KIFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGA
AMGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVF
LGAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFIL
CGVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIAGVA
GVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQIVAERLDHILHDEITETQVDMV
KTAH
>A0A2G6BAG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. P3|TrEMBL
MSLLEKLQTNVLTADGAMGTILYSYGIDYCYEELNVEKPEIIEQIHQDYIAAGADIIQTN
TYSANANKLARYGLESHVTEFNKAAIQIAKRAAAPGGQFVLGTIGGVRGIRKSDATLNEI
EKVVLEQAHALLAGDPDGLLLETYYDFEELSSVVTTLKKITDVPLIAQVSMHDPGVLQNG
LSLNDALHQLESLGADIVGVNCRLGPYHTIQAFDNVTLPDKAFLSAYPNASLLDVEDGRI
VYESEAEYFGRAAVLLRDQGVRLIGGCCGTTPKHIKAAKTQLARLAPITKKIVQPAKPIV
IHEARPVKHQPLHEKAKTERTVIVELDTPRHLETEGYIKGANVLYDAGVDAITMADNSLA
SPRISNMAMGSIVKMQHNIRPLVHLTCRDHNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELLQLIKKLNEGISFSGKPLRKKASFSISAAFNPNVRVIDRAVQR
LEKKIEAGADYFITQPVYTKEKIIEVYEATKHLDTPIFIGIMPLTNIRNAEFLHHEVPGI
KLSEEVLDRMRECGDDREKSTETGLEIAKELIDTAAQYFNGLYLITPFLRYDMTLELYEH
IKEIDQQKERELTHAETSY
>A0A8C6F4Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monodon monoceros|TrEMBL
MDRPKPKVLPAGHCCPSLGMRAWEAGSARFSVPPSISRSSAMVNEPRGHGGPSPRWEGSS
SGSESSKDSSRCPTPVLDPERHERLREKMRRRVESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKRLGLKNILALRGDPIGDQWEEEDGGFNYAVDLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEAGLKHLKEKVAAGADFVITQLFFEADTFFRFVRACSEIGITCPILPGIFPIQ
GYRSLRQLVKLSKLEVPQQVKDVIEPIKDNDAAIRNYGIEQALSLCRELLASGSVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGW
GPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGDNITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQHIHDNYFLVN
LVDNEFPLDSCLWQVVEDTFELLNGPPQSKRETEAP
>D4GDX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea ananatis (strain LMG 20103)|TrEMBL
MSLPGMIYQLTLAGKWFTLSVWTSKRIDVCRLTDNRCGGGSRMSFFHANQREALNQSLAE
LNGRISVSFEFFPPRTSEMEETLWNSIHRLSSLKPSFVSVTYGANSGERDRTHSIIKGIK
ERTGLEAAPHLTCIDATRDELQAIAQDYWNNGIRHIVALRGDLPPNSGKPEMYGSDLVSL
LKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRAITQFFFDVESYLRFRDRC
VSTGIDVEIVPGILPVSNFKQLKRFAALTNVRVPGWMNAMFAGLDEDPETRKMVGANIAM
DMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGIAA
>F7R2I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ligilactobacillus ruminis SPM0211|TrEMBL
MGQTTFSFEIFPPNKESAVEKLTETLDELVGLSPDFISVTCTNKNDDLARLTVKLAGYVK
NRLNVPSIAHLPAAYLDKQQVSEILNELETLGVTNLLALRGDRIEGRKPKDDFRHASDLI
AYVHENFPEFHISAACYPEIHPESDSRVDDIKHLKYKTDQGVDSLITQMFFDNESFYGFR
ECCELADINTPIVAGIMPIVKRNQALRILKTSSATLPKKFTAILNKYRDDPESLKAAGLA
YAIDQIVDLVTQGVAGIHLYTMNDAETAKYIWQATRSLFENGRKVHQV
>A0A3N2E4G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Raoultella sp. BIGb0399|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMSKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A1E2UIL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thiodiazotropha endoloripes|TrEMBL
MNEQTKQQIFSFELFPPKTEKGMENLKTNVQQLQELNPAFFSVTYGAGGSTQQRTFDTVD
WLVEQRIDTAPHLSCIGADEDEILEILARYKAQGINRLVALRGDLPSGTGLGGLGELNHA
NQLVSLIRQQFGDYFHIEVAAYPEFHPQAATPQQDLQNFKRKVEAGASSAITQYFYNADA
YFRFIDECQRLAIEIPIVPGIMPITNFAQLARFSDSCGTEIPRWLRKRLESYGDDLDSIR
NYGIEVVSDLCQRLLAGGAPGLHFYTMNRSAQCQQIWQALGL
>A0A1X7I1F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marivirga sericea|TrEMBL
MKVTEHIANAKNTVFSFEILPPLKGQNIKALFENIEPLMEFKPPFIDVTYHREEYIYRDK
GNGLLEKRTTRKRPGTVGICAAIKNRFDIDTVPHIICGGFSKEETENALIDLDFLGIDSV
LVLRGDPIKSENKFVPDPNGHAYAIDLMEQVVDMNNGRYIDEELQSATPTDFCIGVAGYP
EKHFEAPSMKSDLKILKQKVERGAEYVVTQMFFDNQKYFDFVKLCRAEGIDVPIIPGLKP
ITSLKQMSALPRTFFLDLPDALVDELEKCKDNAAAKEVGIEWCIQQSKELIEFGAPCLHY
YSMGKSDPIYRIAEGIF
>A0A1X7GQD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Pelagibacter sp. HIMB1321|TrEMBL
MNFSIEIGPNSNIETLPALNDVYITMLPGGDYKETANKALELVKKGFNPVPHFPARSMSN
EQELKDYVNKCKDGGVKQALIIGGGRDPVGKFDSSFQLLETGYFEKMKIGIAGHPEGSPD
ISDTDLEKAMIDKKPYADYIVTQWLLDPQPIIDFISKQSVPVHVGITGPLKISSLIKFAN
IVGAKNSLNFLKSNFSKALDLLKPKDPNDLIGKVKSHTDNFHIYTFGGLKETNKWLKENK
YV
>A0A3N9TYR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. YLB-10|TrEMBL
MSAQEHPLGISFEFFPPNTDAGREKLMRNRDLLAERNPRFFSVTYGAGGSTQNRTITTVN
AVRECGITTAPHLSCVGSEKAQLRELLTDYKAQGINSLVALRGDLPSGMGGIGELRYANE
LVEFIREETGDHFEIAVAAYPESHPQAASFEADLQNFARKMNAGANLAITQYFFTADAYF
HFVERARQLGVEAPIIPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSAAIADF
GEEVISRLAQRLLDGGAPGLHFYTLNQAEPTLKIVDNITGRS
>A0A3S8VEW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRIVHQELQRLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVDIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSESIKAFGHE
VIVKLCERLIVGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A2A2QP30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiae bacterium Tous-C4TDCM|TrEMBL
MHIRDILAQRRPTFSFEFFPPKTTAGAEELYRAIVELEAFQPSFVSVTYGAGGSTREMTH
DLVVKLRQTTSVPPIPHLTCVGHSEPEIEEILRRYAAAGVCNLLALRGDPPRDWPDYDWS
DCDFRHAADLVRFIRKFNESGAHPDPQGFGIGVAGFPEGHPATPNRLQELDHLKAKVDEG
ADYICTQLFFDNHDFFDFRDRCRLRGIDVPIIAGVMPVTSLSSMGRMAELAAGARFPAKL
LRALDRAKGDPEAVEKVGIHYAAQQCAELLDHDVDGIHFYTLNKSKATREIYASLGLSTV
A
>A0A7S0GG49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proboscia inermis|TrEMBL
MAPSATETEHAQISTVPKVAPKIIDLINAREGTNKPFVSIEFFPPRTKEGVSNLHARMGR
MLENSSPLFTDMTWGAGGSTAELTLDLTKHMHETGHVANMHLTCTNMAGENGDPIAKVRE
ALTVCKDLGVLNIVALRGDPPNGEETWTATEGGFSCALDLVKFMRKEFGQTFGIAVAGYP
EGHPNAITVLKEGEEANMTPSEKKRCSVIDGVTAVCKDADYIKEMEYLKEKFDAGADMIL
TQMFFDTDVFIQFMADCEAFGITCPIIPGLMCINAYGGFKKMTQFCRTRVPVELSEKMES
IKDSSSAIKEFGVQYGIESCQKLIDGGVKGLHFYTLNLERVVYGITDGLGLTNILTEEGA
KGMDKDAKSMIAVGSAWARVGDVVKCNDGEGIVKEALKDGSVVITLKEKQTEITLAKGSF
EKVVYG
>A0A7D5VHU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NEAU-sy36|TrEMBL
MNPAVTAPAAVGTALLDDFSLEMTGKDVPALQEARDSIPQGTRINVTFLAGEDHAARLAA
ARAVRRCGFVPVPHVSARRLPSRAALEEFLAGLAADGTADNVFVVGGDPARPEGPYEDAL
AVIRTGLLERYGVRHIGISGYPEGHPAITGPALWSALTDKAAAIGAGPFTGEVITQFGFD
AQPVLDWLADVRARGVDLPVRIGVPGPAGVRRLLGYATRFGISTSASVARKYGFSLTNLM
GTTGPDRFLRALSDGYDPTRHGTVKVHFYTFGGLRTTAEWITDFQRRAR
>A0A6G2MSV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID4946|TrEMBL
MALGTASTRTDRARTVRDMLAGGKTTYSFEFSAPKTPKGERNLWTALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGAWVAHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVEAGCDTPVIPEILPVTSVRMLERLPKLSNAQF
PDALKERILAAKDDPAAVRSIGIDFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHHPPQA
>A0A4Q2KGY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagerythrobacter rhizovicinus|TrEMBL
MSPTFNQMQEARTALDAPLFSGLPGDIDVSFEFFPPKSEKMAQTLWESVQTLAPLGPRFV
SVTYGAGGSTRERTHEQVVRINRETDIPAAAHLTCVQATRGEIDEIARHYWESGIRHVVA
LRGDPPDGQSRYTPHPGGYANAAELIAGLRAVAPFEISVAAYPEVHPDARDAEADLDNLK
RKLDAGATRAITQFFFEPECFFRFRDKAVAAGIDSEIVPGVMPVMSFASVQRMAGLCGTA
IPAWMEGLFEGLDERPAARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRPKGIPDDR
>D4K7S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii SL3/3|TrEMBL
MLDVRKLLAQRPLLFDGGMGTYYKAKPGQECEQANLTDPEGILAVHRAYLAAGADAIKTN
TFSLPRLAAAQQPGWEQLADAGWQLAVKAAGETGAAVFADLGPAPDTENLPAEQVYLAVA
KRFALLGARNFLFETLSAEDGVLEAIRALKQTVPEAFVLVSFAVLPDGYTREGRYCAELV
RRVAQSGVVDAVGLNCVSAPGAMRALVQQLGDAGLPLSVMPNAGYPVVARAQVRYQGKPE
YFARELSRLASEGVRILGGCCGTTPQHIAALRTALDALPEVLPAAPAAKPAVAAKPAVET
DDAFLRKLRAGQRVIAVELDSPKDADLTAYLEGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGMNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPITVFGALNLNARNFEVELRRAAEKLENGMSGFL
TQPVLSAQAVENLKKTRETLGERAKILAGILPVVSQRNAIFMENEVNGIHVDDAIIQRFE
GLDRAAGEELGLEVSVQAAKAAAPYVDGFYLMTPLTGWR
>A0A5C2HAW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malaciobacter pacificus|TrEMBL
MFETLIKKLQEDKFLTLETTPQHEPSMHNIIEKIKKFNLQDKVDGFSATDNPLAKLKYNA
LFASLKLQQEFNKPVIATMSMRDRNKIALQSDLMGANDFDVRAILALTGDPAKMSDQPHS
KGVFEANSIMLLKMIKSFNYGMDFAGRPFKIEPKQIFPFSVTNSYAKSYASIEKKMHNKI
QNGTLGIISQPVFDVETAKKLLETFENAKEGVEGEKQKAQLIFGVFPITKLRTALFLSAQ
VPGIKVPQYWIDALESAHNISEEEEYKVGMDLSRDLFRELNKFHPKIHLMTANRFDVANE
VIS
>A0A089L9N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus borealis|TrEMBL
MKPDLRSAWENNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYIEAGSVL
LESNTYSANYDKLSKFGLESKVAEINRAGIRIARTAAGENGYVVGAVGSIRAGKRANLSS
AELKRFFSQQIAALLEEQPDGIMLETFYDVEELHLALRTVRKLSELPVICQLAVDDSART
LDGLTLPEAFRILEQDGADVIGFNCNTGPNGIKRALGTLQGRLVLPVSIYPNAGVADYVD
GQYRYGASPEYFGQMAPVFADMGSRIIGGCCGTTPRHIAEISAALKEYEVKPLPEPDEHT
MAERISVHEHLSEDDGQGGAEPTLVDLVKERHTVIVELDPPRDLDIAKFMRGAEALRRAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIRQLNDGVAFSGKPLKQKAKFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIARIAKATEHLDIPIFIGIMPLASGR
NAEYLHNEVPGIQLSAEVRSRMQGLEGEAGRAEGVLIAKELLDAATAHFNGIYLITPFMF
YDMSVQLLEYVWAKQGRKLSPLFR
>A0A139CIK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanohalophilus sp. T328-1|TrEMBL
MSLKTNVTYYPAMPSAFKEKLLSDEFIVTSEISPPKGVDVSSVFEEAGLVRDYVDAFNVT
DNQRAVMRMSPLAMGHLLKEQGLDIIMQFTCRDRNRLALQSDLLGAYAMGMENVCIMSGD
YPTKGDNPGAKPVYDLDSVQLLGTINRLEKGFDIAGNPLESVPSFTKGAVCNTEPDLPLQ
LMKLEKKARMGIDFFQTQAVYDIGHFETFMDSISHMEVPVLAGLIPLKSAHMARFMNEKI
PGIQVGDELIARMESSTDPAEEGLLICAEQVRELKKVCRGIHLMPIGHYRQITALFEMAG
LYEKD
>A0A1H2EM81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobium sp. GAS474|TrEMBL
MNLLDELEERILVGDGATGSYLHALGVPAGACLEEANLSQPDLVTKVYDDYIAAGARVVE
TNSFGANRLRLARYGLDGKVSEINWKAARLLADAAKGKNVYVGGSVSPLQVRPTDPVLTD
DDRRSLYREQIGALLDGGCHLLFLETFTELSELLLALDVFQNLSNVPVVTSLGISEEGRL
GSGEDFQTAFRALRKAGADIVGVNGTCGVQASLSLFDRLELGIDDVAAAYPNAGKPEFYE
GRFNYSASPEYFAANAPLFVERGVRLLGGDYGTSPAHTAALAAAVADLKPRKGGKPARPL
RVSTVEAKPQPLAPQAPVEDSLLERLKTKPVTIVELDSPKTLSMEKFMEGARSLDAAGAD
AITLADNSLAILRVSNLAAAVLIRRELKAIPLLHLACRDRNLLGLQSEVMGLGALGFRHL
LAITGDPAKFGDHPGATSVYDLNSIGLLKLLEGMNRGVNAVGKDLKGKTDFVIGCAFNPN
AKNFDSQVKKLESKVKAGAQYVMTQPVFDAALVKKTVAAVSALGVPVFVGLMPLLNARNA
EFLHNEVPGIVIPDAVREQFRHAADDKAAAECGHRFAAGIRDEIRAHANGTAGGLYLITP
FLRYEASVRLMQG
>A0A318H7R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycolicibacterium moriokaense|TrEMBL
MTGFVDALREKSLVCDGAMGTMLHAAGNSLDRALPELNLSNPDLVSTVHESYVDAGVDLL
LTNTFGAGRLRLSEHGYADKVCEINRAGALLARAAAGSTHRTVFIGGSIAPQVSASQRAT
VSANERIEAVREQVTVLAEAGVDLLVFETFGYLDELLEAVRVAVEVTDLPIVAQASFTAD
GCTLGGESTHEVATALAQLPIVALGANCTVGPQRMLAVVEELRRYTTLPISAQPNAGLPR
RMQGRRFEYSLDPDYFVRYALRCVEAGASIIGGCCGTTPAHMRSVTTALGHRVALAASRP
VRRAAPDEFLRHLTARGFIAAAEIRPPISGAIDDAADMAGALRDQGAGLLLISAVRGPRS
PLSSAGLAQRLQQQLGVETIATMTTWDKTIMSLQADLLGAHAFGTRTVLCETGNPPLRGD
YPNADGIWEVDSVGLISLVAKLNAGRDCNGLSLATKTAFHIGARCNPGAENLDAEITRTR
AKIAAGAQFLITRPLFELEGLSHLLDALGEDRVPVLLTVSPLSGFAEAEYLAYEVPDVTI
PHETLAALGAAGGDERATGERLATDVVTAARSLADGVIIVAGDERQMTQRLLASARV
>A0A2H5WK28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR13|TrEMBL
MPITNFKQISRFASMCGATIPDDLIKRLEPHMDDQEETTKIGVEFAIKQCEDLLKNGVPG
LHFYTLNKSRATLEIYQAIKDKILALRSYLS
>A0A2N5XBE7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DJ|TrEMBL
MALGTSSVRTDRAVTIRELLASGERSYSFEFFPAKTEQGERTLWEAIRRIEAVGPTFVSV
TYGAGGSSRDRTVRATERIATETTLTPVAHLTAVDHSVAELRNIVGQYADAGIRNMLALR
GDPPGNPQGEWVQHPQGLRYAAELVRLIKESGDFCVGVAAFPEKHPRSADWDSDIKHFVA
KCREGADYAVTQMFFHVEDYLRLRDRVQAAGCDTPIIPEIMPVTNVRQIERFAQLSNADF
PAALADRLNAVRDDPAAVRAIGVEYATRMSAELLEQGAPGLHFITLNHSPATLEIYQNLG
LHQRTT
>A0A2Z5BRM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. PM5|TrEMBL
MTSHEPHIAAARAGGEASPQVPFSFEIYPPRTLAQLPALHETIRVLAEAGPRFISVTFGA
GGSTTDRSLAVLTHILRETRVPPVAHVTCVGSSYAEATTVIRHFLDAGITRFLAVRGDPP
LGVGEDDIVFGDLESAAQLVQLIGRVHAERSTYREREIPGVPGAVRVIDGDRVDIAVAAF
PNGHPRSRHRYEDIDALLAKQAAGATSAITQLFFHADEYLDFVARARAAGVVIPIVPGIM
PITSPGRLRRVLELTGDARPDSLAAALESAPDAAAQREVGLAHAAALARAVVAGGAEGVH
LYAFNNHETVLGVLRTAGLIPERRS
>A0A435AUY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.11.2.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A1M6KN56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides stercorirosoris|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAGAIQNKYNITVVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESAFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKITKTPFSYGVACYP
EKHEEAPNIDTDIYWLKQKMEAGAEYAVTQLFYDNRKYFDFVERTRKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELAREAMKCKTDEEARQVGIEWCVQQCKELMEHGVPSIHF
YSIGAVDSIKEVAKQVY
>A0A2J0L684|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium CG07_land_8_20_14_0_80_42_15|TrEMBL
MSLLKEKLNSGKFAITGEIAPPKGTDVKEILEDAERMKNRVDAVNVTDIQSSVMRAGSLV
LCHLLKQKGIEPVYQVTCRDRNRLALQSDILSAAILGIENVLILTGDHQGLGDHPQAKGV
FDLDSVTLLEVVKTLQSGKDMVGNELKGKPSFCVGAVVNPGADPLEPEIIKMEKKIKAGA
EFFQTQAVYDPALFERFMNAAKHLNAKILVGIVLLKSAGMAKYMNENVAGVFVPDELIKE
IQSASKEDRPKKSVEIAARLIKEMRGMCQGVHLMPLGWDKLVPGVLDQAGL
>A0A6G2ZNB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID3915|TrEMBL
MALGTPSTWTDHARTVRELLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTREGTVRATQQIAADSTLTPVAHLTAVDHSVAQLRNMVGQYADAGIRNILAVR
GDPPGDPMAEWVEHPEGVRYAADLVRLIKESGDFCVGVAAFPERHPRSADWDSDIRHFVD
KCRAGADYAITQMFFHPESYLRMRDRVVAAGCDTPVIPEVMPLTSVRQLERFPQLSNASL
PSALKDRILAVKDDAAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A6M4WKE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces asoensis|TrEMBL
MALGTASTRTDRARTVRDILATGKKTYSFEFYAPKTPKGERSLWNALRRVEAVAPDFVSV
TYGAGGSTRATTVRETQQIVVDTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGTWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSGDWDTDVAHFVD
KCRAGADYAITQMFFEPESYLRLRDRVEAAGCVTPVIPEVLPVTSVKMLESLPKLSNAHF
PAALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A7W5ZYU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium hassiacum|TrEMBL
MAAPVIHPNWDKQPAGITDGFSLEMTAKDEASLRDAAPLIPAATPIAVTFLPGEDVAARV
AATVAVRELGFEPMPHFSARRITSEDDFEGYLKAVVEQAGVERCFIVAGDPPEPVGPYFD
TSALIATGAFERSGIKAIGIGGHPEGHPNMTVEQTWAVLEAKVAEIAARGMAPLIVTQFG
FDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLSFAARCGVGASTSVLKKYGISVAN
LLGTAGPDKLVDAFARGLGPEHGRVRLHFYPFGGLTKTLEWLHAYNRKHGLAA
>A0A4Y7RZP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelotomaculum sp. FP|TrEMBL
MKYLSKLQAILEGGHFAVTTEIGPPKHAGAHGLKYTAQILKDFVDAANITDNQTAIVRLS
SIAAGVHLLANALEPVAQMTCRDRNRIAIQSDLLGAYSLGMRNLLCISGDHQQFGNHPTA
KNVYDLDSIQLVNLMSRMRDEKQFFCGEEIKEYEPRFFIGAVANPFADPFEYRVDRLEKK
IKAGAQFIQTQGVFDMERFERFMELVRARGLDQRAHILAGVIPLKSWRAAKFMQTQVAGM
IVPDALVDRLKNAADPPSEGVAVCIEQIKYIRENIKGVHGVHIMAIAWEDIVPEIVKQAG
LYPRPEVVLD
>A0A849NE90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteriae bacterium|TrEMBL
MKVTEHLAKAKNTLISFEIIPPKRGGNIQSLMSVLEDIVKYNPPFIDITSHAAEVMYEET
PDGGYRMKVKRKRPGTLGICALIQNKYNIDAVPHVICQGFTREETEDFLIELHYLGIDNV
LAIRGDDSGFNKPIKFGRSTNKFAIDLVRQIKDINEGKYIEDSLLDAYSMDFCIGVGGYP
EKHFEAPNLKTDIKYTKQKIDAGAEYIVTQMFFDNKKYYQFVDQCRAEGIEVPIIPGLKI
LTNKSQNAALPKNFFIDVPDELSNEIMEAKPEHVLDIGVEWTYKQVEDLLNHGVPSIHFY
IMQKAKPINMLMKKLNI
>A0A2N9LCJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfotelmatomonas gaucii|TrEMBL
MSSPLTFSFELFPPRTPEAQAKLPSTVAQLAAVRPDYFSVTHGAGGSGQEGTYETLLTVL
EHTGVEVAPHLTCVGSTHANIAAQLQRYREAGVKRIVALRGDLPATAMSASAPGEFHYAN
ELVRFIRAEHGNAFKIEVAAYPEMHPQANRPSEDFDNFRRKVEAGADAALTQLFYNADAY
FDFIERCAKAGITIPIVPGIMPITSHANTMRFCNGCGADLPRWVRLRLEELQDDKAALLD
FGLSVVTRLCETLLKNGAPGLHFYTINQSSPSLRLWKSLALSVPA
>A0A3C0NEM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanobacteria bacterium UBA8543|TrEMBL
MRDIIQDTQLEADTKPLPRENYLKGTASTQNTLRTAVESGEFLITAEVTPPKGGDPAHML
KMAKLLKGRVHAVNITDGSRAVLRMSSLAASVILLQHGIEPVCQMACRDRNSIALQADLM
GAHALGIRNILALTGDPVKAGDHPEAKSVFDLESVRLLQLIAKLNSGYDLNAKPLTDGVT
DLFVGAAVDPQLKSWSSLQKRFERKLEAGAQFFQSQLISDFDRLEKFMDEIAASSGKPIL
AGVFLLKSAKNARFMNKYVPGVNIPESIIERLAAADDPLEEGVKIAAEQVQRAQQICQGV
HMMAVKREDLIPKILDLAGVVPVRS
>A0A0Q5VUK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Leaf371|TrEMBL
MSGSPVDLLPGHSSRGRLEQVLRRGEFAVTAELNPPDSADPEEVYARAAVFEGWVDGINA
VDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQGDVLGAAAMGVANILCLTG
DGVQAGDQPGAKPVFDLDCMSLLETVRIMRDHAKFLSGRKLTAPPRVFLGAAINPFAPPY
DFRPYRLAKKIEAGAQFVQSQYCFDVPMFRAYMDKVRDLGLAEHCHILVGVGPMASARTA
RWIRSNVPGVHIPDAIIARLEGAADQKEEGKQICIDIINEVKEIKGVSGIHVMAYRQEEY
VAEIVHDSGVLKGRRPWRREQDPADAGVAERLDAARGGEMQDQESLAETAAKRPH
>A0A417R2U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia sp. OM07-19|TrEMBL
MASVKLTELMKERQLLSFELFPPKTDKGMENLPGTIEHLCQFDPEYISVTYGAGGGNVGA
NREVCQMVKKAGTVPVTHFTVIKNTKEGIRDQLETYLSEGVDHILALRGDFPRGEHSTGG
DFNYATDLVKFIRREFGDKFEIAVAGSPEGHIACRSLDADVSVLKMKQDNGADYIMTQLC
WDMEQFARWQDKIRKAGVTMPIDVGIMPILDQAATISMALSRNGCVMDRELSRLISKYWI
FPNPFDKAPFDDNLEQKKEDFKKAGIEYTIRQIDKYRALGVEGIHLYALNKWKDVSEIIN
ASGMRTLI
>D2B6I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)|TrEMBL
MALGRPSILPDRVPTVRELLAAGGRSFSFEFFPPKTDEGERQLWRAIRELEALRPAFVSV
TYGAGGGTRDRTVGLVERLAHETTLTPVAHFTAVNHSIRELRHLVGRFADAGVRNILAVR
GDPPGDPTGEWVRHPEGVLYADELVRLIRQAGDFCVGVAAFPYKHPRSGSVEADTEHFVR
KCRAGADYAITQMFFQADDYLRLRDRVTARGCDTPIIPGIMPVTQMSTIARSEQLSGAPF
PAEVAARFEAVAHDPAAVRQLGVEHAAELCQTLLDEGVPGIHFITFNRSSATREVYQALD
VAPAKAVLTA
>A0A2G5QRV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. FWC2|TrEMBL
MTLPPTRRVIGPVARAGERSYRPRVSFEFFPPKTPAMEESLWQAITRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILDETNLKPAAHLTCVGASRDEVDEVIREYWETGVRHIVSLRGD
PPPGEGGIGGVYVPRADGYANATELTKALRGIAPFEVLVGVYPEKHPESPSLEHDIDVLK
QKVDAGATLGISQFFFDLDAFLRYVDKVRAAGITIPIVPGIMPVTNFAGLKKMAAACQTA
IPSWLGNLFDGLEHDAETRRLIACSVAAEMCAKLQEQGFEDFHFYTLNRADLVYAICRVL
GVRETAPAPAEAAA
>A0A2Z2P0G3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulosicoccus antarcticus IMCC3135|TrEMBL
MNGFEDESVPGYHSHILPGHSSPGRFERTLRAGHFVVTTELAPPDSADPAAVYERAAVFD
GYVDAINATDGSGAHCHMGSLAVCALLTRLGYALIQQISCRDKNRIAIQGDILGGAAMGV
CNLLCLSGDGVQTGDHPEAKPVFDLDCMSLLEIARTMRDKSTFQSGRKLDHPPRIFLGAA
ANPFVEPFDWRPLRLAKKIAAGAQFVQTQYCFDVPRLKAYMDKVRELGLDEKVFIIVGVG
PLASARSAEWIRNNVPGVHIPDSVIQRLKGAADQKAEGLQLCIELIQEIREIKGVSGVHV
MAYKQEHNVPDIVTRSGALNGRKPWHPRTYDGDATVQQHLENLQ
>W6JXD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tetrasphaera australiensis Ben110|TrEMBL
MDTVSIPTDLRAERPSVSFEFFPPKDDAGEAVLMDAIRRLERARPDFVSITYGAGGSSQD
RTVHVTERIARETTLTPLAHLTCVGASVAQLRNVVGQYAAVGIRNILALRGDPPRGGDGT
WVAHPDGLSHADELVRLIRSLGDFTVGVAAFPDVHPESPDFEHDVEVLIRKADAGAEFAV
TQMVFDASTYLRLRDAVAARRDLPITPGLMPVTNVKQIARMSELMGTPLPEAVVSRLAAV
EGDPEAVRQVGVEIATELAEAMLAEGAPGLHFITMNRSTATLQVYENLGLTAAR
>A0A7D3QQY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter curvus|TrEMBL
MLIQKIKNNEAGILLYGLTPPKENLTGEETAAIAAKQIARLEGQNIDGIVLYDLQDESSR
TNEERPFEFIKTTPPETYYETYLKKHFKAVIYKAVGKYDEPEFCEFLRHRQEDLICVFVG
ASSKSQEVKLKLDEAYALKAKFAPNITLGGICIPERHASKLDEHLKVAHKSEKGCEFFIT
QAVYNLENAKKFIDDYAKLEGKKCPIIFTFTPCGSAKTLLFMKWLGINIPPNFEERLNAS
ENILQTSLNLCLEIFNFLYKYGLAKGISVGANVESVSNRKVEIEASITLLKQIQEIIAKT
NTAYHWIGVGI
>A0A7J9VBS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinophytocola sp|TrEMBL
MSNQPLPKVPRKRRAVAPLLAAPRYEILPLPRAREATEQLPVGSVVTVTASPHKGLHATI
DTAEDVAAQGMRAVPHLAARQFHDSAELSDVLDRLASAGIDEVFVVGGDGEQPAGDFPDG
LALLRAMASLGKLPAEVGVPSYPEGHHAIDGATLWTSLLAKQEYATYTVTQLCFDADAIC
RFAADAQRNGVTLPVVVGMPGVVDITKLLRVGLKIGVGDSLRFARGNTSVAGKLLRPGGY
RPDGLVRKLASRVASGDCSLAGLHFYTFNHVAATARWVRNTHRRAA
>A0A7S1VVN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Grammatophora oceanica|TrEMBL
HEEANVRQALVIAGGVDKPVGGFDSSAQLLDTGLFEDAGFSHLHVAGHPEGSPNIDGESL
LDALKWKNDYAKHSGAEVAITTQFGFDSSAIVSWMEELRDHGITLPIHVGVAGPTNLPTL
LRFALLCGVGPSLSMIQTRAKDVSNLILPYEPS
>A0A0B2FD48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. IHB B 3415|TrEMBL
MKPDLRSAWENNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYMEAGSVL
LESNTYSANYDKLSKFGLESKVGEINRAGVSIARRAAGETGYVVGAVGSIRAGKRANLSS
AELKRFFSQQIAALLEEQPDGIMLETFYDVEELHLALRTVRKLSGLPVICQLAVDDSART
LDGLTLPEAFRILEQDGADVIGFNCNTGPNGIKRALGTLQGRLVLPVSIYPNAGVADYVD
GQYRYGASPEYFGQMAPVFADMGSRIIGGCCGTTPRHIAEISAALKDYAVTPLPEPDEHR
MAERISVHEHLSEDEGQGGAEPTLVDLVKERHTVIVELDPPRDLDIAKFMRGAEALRRAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIRQLNDGVAFSGKPLKQKAKFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIARIAKATEHLDIPIFIGIMPLASGR
NAEYLHNEVPGIQLSPEVRSRMQGLEGEAGRAEGVLIAKELLDAATAHFNGIYLITPFMF
YDMSVQLLEYVWAKQGRRLSPLFR
>A0A3D5L8E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp|TrEMBL
MNLREYLKETNLITDGAFGTYFAAKYQTQEIPELANLSDPEKVKKTHEEYLNAGANFIRT
NTFAANTETLQESFPEVEKNIRAAVEIARSAADGKNVWIAGDIGPIPVNGTEDAAAAADE
YYQIAKTFAECGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDVVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIGELSSWDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLNVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTKEDAARLRRIKEETGATILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>A0A2E3AH96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MRISYEFFPPADLDFSRVASHFNELKVFQPKFISVTFGAGGSPEDKSLGLIKELQAHTNV
DVAAHLTLVGKSIDDIDAIIQKLKILNVKTIVAIRGDSPNNLFVPVKKGFINTSDFVAYL
KRNGFEVCVSAYPXPHPESEGFDFDLQLLQNKVEAGASKAITQFCFDLPQFDRLVESIAQ
KNINVKLIPGIMPVASIKNILRMADRCGIIIPKSVTNRFNGNLREDIKAAKELCLEQIEY
LQNLGLDDFHFYTLNRSDLTYSILKEIKANEIHEHKSRNAKSWQEERIKIRN
>A0A1B3Z7S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas panacis|TrEMBL
MTISVSQLEEARRALEAPLFADVAGDTAVSFEFFPPKTPKMEEALWETVKTLEPFGPRFV
SVTYGAGGSTRERTHATVARIQAETGTPAAAHLTCVEASKAEIDAIADAYWQAGVRHIVA
LRGDAPGADGFVPHPDGYTNAADLVAGLKRLHPFEISVAAYPECHPDSRGVSDDLDNLKR
KIDAGATRGITQFFFEPETFFRFRDRAIAAGITAEMVPGIMPVTNFASIVKMSAMCGTEV
PAWLGRLFEGLEDHATARQLIAATLAAELCRKLYAGDVRALHFYTLNRAELSFAICHMLG
LRAKLPAKVAVAA
>A0A3D5S9F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Collierbacteria bacterium|TrEMBL
MLEKSAERLTPPEYLKQWITEANYEVLPTEKALDLINIIPETNTISVTCRPTGIEETVHF
AEMLGPEKMKRVWPHLAARRIYSQDHFDEVSLRLINAGMEKAFIVGGDGDPSFEDFKKTE
DVLNGLLIRGILPKKIRIGGYPEGNPVMDMDPIEVLLQKQEFAEKAGVQMEIVTQMFFDA
DTLFNWLMEIRQRGVYLPVELGLLGKLKWNSFVKVLETIGIKDAMAFLKSKPKLAMSLAT
GMITGFSPRYLLTELAEKNTPELGINGISIFTLGNITNSVKCLTDIASENI
>A0A3C1B632|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MNTPEISFEFFPPASLNDSFRLWNTINALEGFQPKFISITHGTGNKPRALTQDLVETLLE
HKDLTVAAHLTCVDMSA
>A0A3D1FJQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp|TrEMBL
MKIKDILSQGKPTLSFEVFPPKTEDKYESVEQAAAEIAKLKPAFMSVTYGAGGGTSQYTV
DIASTLHHQHHVTALAHLTCVSSTKEKVHQVLGELKAAGIENVLALRGDMPTDAPAKREY
HYASELIREIKEAGDFCIGAACYPEGHVESASKTIDMDYLKQKVEAGCDFVTTQMFFDNN
ILYNYLYRIREKGVTVPVVAGIMPVTNVRQIIRSCQLSGTYLPSRFKAIVDRFGDNPAAM
KQAGIAYATEQIIDLIANGVNAIHVYSMNKPDVALKIKENLSEIL
>A0A1A3EL16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. 1482292.6|TrEMBL
MPADSGCPKRMEFGPCGGVRPDGQCEMRPGPCVFDDVVPWSGHSPAPRPARTPRVLTDFS
ATPFDPDDIAATATVLAPGCDAVLVGEHQNKPDFPPTLMASLLLDAGVTPWITLSCRDRN
RVVLEQELRGLRSIDVETVLCVTGDGRGYDVRPDVSQAFDLDGPRLVSLAASVGIVAAVP
ETPTAPPVQRRPARLVEKQRAGASLAVLNHVPFPDMVADFMKSARAAGLAIPVIAAVAVF
TDTVSAAVLEGLPGLELDPTVTQRVLGASDPVEAGIAAAVDEARALLSIEGVEGVNVSGL
ASASGPRIGAEIKAEVGRRIREQGGGAP
>A0A642UQS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diutina rugosa|TrEMBL
MRISEKLKQAHSITNPPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPVFIDITWNAGG
RSSTLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALKKAYDSGCQNILALRGDPPLD
GSESTGDFKYAKDLISYIRKNYGDHFNIGVAAYPEGHPEEEDEEKVLRYLKEKCDVGADF
IITQMFYDVDNFLTWCAKLRKIGIDLPIIPGIMPISTYAAFIRRAKWSEVSIPQHFLDVL
EPIKDDDFLVREKGTELVSEMCRKMIDSGYVNHLHFYTMNLEKSTVMVLEKLNLIETIKS
HESLGGAVLPWRKSLHPQRSKESIRPIFWQNRKYSYVSRTATWDEFPNGRWGDSRSPAFG
DIDLSATDLLRQSPKKAYDLWGVPSSVADLSKILISYIKGDLKSLPWSDGPIGSDSAVIR
EHLINLNRKGIFTMNSQPALNAVRSNDKTYGWGPKNGYVYQKQYLEFLCPKGLLADLLLK
IDNHNKSQSESASSVISYYAVNKDSTLWTNCDDDDINAVTWGVFPGEEILQPTIVEKTSF
LAWKDEVYSLLQEWGNIMQASVVEIDDDTRRNFIDFVSQFAENYVLVNLVNNDFIDDNQA
MFGLLEELNLPDLI
>A0A2E1RXR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium|TrEMBL
MNISFELFPPATSNGIGKVVEIARQLADFQPDMISVTYGAGGSGRERSSRLVAELNKPSF
PAITAHITVSGQSKQDVLQQMDEWQEHGVKRFVALRGDMPDMARPFKPHGDGFSSSLDLM
AHLASHGAEEIYGGAYPEGHPESPSQSAELDHLKAKQDAGATALITQYFFEVDCFLRFRD
RAESHGITLPIIPGILPVANFEKAKGFSKRCGASIPQFVHDRFAGLHNNPHESALMGASL
TAELVMELADEGVEHFHFYTLNRADLSLTACRMLGVRPT
>A0A388TKL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Termititenax dinenymphae|TrEMBL
MKLAEIYSQNKPVISFEVFPPKTDDGLAPLIAELRKLKEFKPGLISVTYGAGGTTQGRSL
KLLEKIVNELKLELMPHLTCIGSGEKSILNFLQKISGWGVENILALRGDFPKNNPDYQPE
SDVFKHAADLVKFTKQNAALSMAVAGFPEKHPEAVSLETDLQYLQAKVHAGAEAIFTQLF
FDNQYYYDYMKSVRATGITVPVIPGIWTITNLKQIQKTADLSHAKIPDDLLNKLQKADEA
EVPEIGIEYAAAQIQDLLTHGVPGVHLYTLNKAETVSRVLEKIHWINI
>A0A545TKH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Denitrobaculum tricleocarpae|TrEMBL
MNVFSSAAPAATFSSLSEADPMKQQIIDFMRDFSIETTPGSALKIPDYREHLRPGAKVAV
TFLPGSDFADTIATAKRLKEEGFQPLPHFAARSIVSAAVMEENLKKLQAEVGIDEVVALG
GAVDTPLGEFESSMDLLETGLFDKYGIREIGVAGHPEGSPDISPQGLKDAITWKNAFAER
TGAKLYIATQFCFEAAPIIAWDRAIQAEGNKLPIHIGAPGLATIKTLINHAKACGVGPSM
RFLTRQAMNVAKLMTVNAPDKLIMDLAQYRAEDPNCGIAKVHMYPLGGLKKSAAWSYAVV
DGDFTMDPKGKGFKVTRDIG
>A0A1I2PVA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planifilum fulgidum|TrEMBL
MGEKRCLKEHLKEHLLVGDGAMATYLYQQGVPVGLCYEELCLTRPDLIREVHRAYFEAGA
RFLETNTYGANRERLARYGLEGKVTRINRAAVTLAREVAGTEAFVAGAIGSILAGRVPRY
DEDEYRDMYEEQATALLHAGADAILLETFLDLEELLLAVEVIRPLTEAPLIAQLALIEVG
RTRDGYPLTEAFRRLKEAGVDGVGLNCRLGPAECLRSLEQAVVPEGLYLSAFPNAGRLGI
TDGEYRYKSSPEYFRESALRLREQGVRLIGGCCGTTPRHIRAMAEALKGLSPLPRINPED
ASPEGESVSLAVQPPRKDPAITEKVRTGRTVIVEYDPPRDLDIDRFLHGAARLKEAGADA
ITLADNSMATARMSNMALGAILKSRGIEPLVHITCRDRNLIGQQSHLMGLWALGIDQVLV
VTGDPTRIGDLPGASSVYDVSSFDLIRMVKQLNEGISFSGKPLKQRARFVVGAAFNPHVH
NLEAAVRRLEKKVEAGADFVMTQPVYDPETIRRIHEATRHVGIPVFLGIMPLTGFRNALF
LHNEVPGIKIAPEVMERLRRCRDKEEGRREGVAIARELVDAALEYFQGIYLITPFFHWRM
TAELTRHIRERDRRHAAVGE
>A0A7H0FCR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leclercia adecarboxylata|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPHWMAKMYE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>X6DF78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNHC252B00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDDMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETDIPAAAHLTCVGATRDEVDAVIQDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKSIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEATAA
GSAAA
>A0A3A4CW68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dickeya dianthicola|TrEMBL
MSFFHANHQEALNQNLAELQGRINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRNELKAIAQDYWQSGIRHIVALRGD
LPADGGKPEMYASDLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTTGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTAMFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRSELSYAICHTLGVRPVTAA
>A0A1M5NP43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium oranimense|TrEMBL
MKITEHIKNANGKTLFSLEVVPPQKGIGIEDLYTNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTPGGHASAMDLVHQINDLGRGKYLHNDETVCDELNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKRFIEFVKKAREMGITVPIIPGI
KPIATKKHLKILPQVFKIDLPEELITEVENAKNNEAVKQIGIEWAIAQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>E6SSQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides helcogenes (strain ATCC 35417 / DSM 20613 / JCM 6297 / CCUG 15421 / P 36-108)|TrEMBL
MRVIDLIHSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREDTEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGNGYHHAIELQDQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNINTDIYWLKKKVEAGAEYAVTQLFYDNRKYFDFVERARKEGITIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTKEALKCKNDEEAQQLGIEWCIQQCKELMAHGIPSLHF
YAVGATNSIKEVARQIY
>A0A2N2F725|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-9|TrEMBL
MQENRFKEALLNPSAFPVTWELVPGRGARETAQDKALALAAQAASNNHIYALTLTDNPGG
TPAMSADFMGSEIVKLGIEPLVHFTCKDKNRNAIESSLYALDRAGVRNLLVMSGDYPVSG
FRGRPAPVFDLDPIHVLQLISDMNRGLEYPGMKDTIRHRPADFFAGAVVSPFKATEAEQI
VQYSKLKKKIEAGARFIVTQLGYDARKFHEVLLYMKQNGFDIPLIGNIYILPFGAAKMMN
RNDLPGSVVTDKLLADLDRERNDPDKGQGARILRAARMYAILKGMGFSGVHIGGHNIKYE
QVDAIIDMGESLTSQWKDLVQYFDYPIDGGFYYYEKDPETGLNREVPGKLINNLSDVKIG
CSYGFSRFFHRLMYEPGKNLYGFMKRLCGKVQGTKMEGPFHKMEHLTKVALFDCRDCGDC
ALIDVAYLCPMSQCPKNQRNGACGGSYRGWCEVYPGKRHCVYVRAYARLKKYGEEGQLSR
EIIPPCNWDLYQTSSWINYYQGKDHTSQKLSDKSS
>A0A6P8Y9P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila albomicans|TrEMBL
MHPIDLATTNSLRPTSPLPASIQPCFKFTGDQQELTPSIAELVAQKTAQKEFFYGIEIMA
QNEGKAHCVDFHDFLPLLPSFISFVWLKQFTDAIRRTGNFDDVTSIQLIPHLNSHIAAMP
HLSLYRLTQQHVDAFAALNLSNVLVVRGDSLDEQQDYRYAYQVVEYLRRVRGDNISIAVG
GYPEGYTSLTSDAPNKTQDMKYLKQKIDVGANLIITQLCYSGDKIIEFIKDARIAGITVP
ILVGIIVPYSFANYQIIERITGVRLSPEARIEVEQLSSDDTKVKDYFVQLMVRIIQQILE
ADLGIYGIQFFTLNHIEPTVEVLRELRLRGIPKETAADD
>A0A833GJY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dokdonella sp|TrEMBL
MAHVPVSFEFFPPKTDEQREALEASLPRLKAQQPEYVSCTFGAGGSTLSYTPETIRHLRE
VHGLDAAPHLSCMGGTRAEIASLLARYRELGCRRIVALRGDLPSGMASHGDFRHASDLVE
FIRREHDGHFHIEVACYPEVHPQADDAHADLRHFKAKVEAGADGAITQYFYNADGYFRFV
DAVRRFGIDIPITPGIMPIANFTQLKRFSDMCGAEIPRWLGKRLHALGDDVEAIREFAAE
VVAELCDRLVAGGAPGLHFYTLNRSKPTLAVIERMRSRA
>A0A415WYQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. AM16-25|TrEMBL
MKIGEFFKENTLLCDGAMGTYYASKFHDETLVERENFEHPERIAQIHGEYLESGARLLRT
NTFATNSNFFSSVEEMENNIMIACQIAKSAVEAYYEKTGLTKETYPVYVAADIGTIYDME
QKDDSNVLAEYHHIVDTFVSAGMDIFWLETQVDVYYLKRLLAYIKEKAPQAYVMVSFSMD
KTAYSKGGLQFDRMVRLMSEMDEVNAYGLNCGMEAAHMYQLLKNVTFPSEKPVIALPNAG
YPYQLRGKTIYGKNESYFQKMLLQIADLGIDLVGGCCGTTPDYLKEIAEQLKGKKKMEKK
TGSPETPAVSRTESVFWKKLQSGEKPFVVELDPPSDIKVEKLVSGAQLLKEHRVDLLTLS
DSPMARSRMDASLLGSKIQRETGIYVMPHLSCRDRNVISLRGTMLGDYVNDLRHFLVVTG
DPIAQNDRNTITQVFDYNSIKFMGLLQEMNEDQFYQDRIVYGGALNYQGVGVDAIARRMK
LKMEQGCSFFLTQPIYADADVERIKDLKDRTGAKIIGGIMPLVSRKNALFIANEMPGMHV
PPETLAYYEEGMSRSEYEEVAIRVSVEIARKMSSIVDGYYFMTPFNRVELICNIIERIRE
ENL
>A0A7Y8L7X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacterales bacterium|TrEMBL
MIMIENFIQKIQNSKMLSFEISPPKGANFDETLQKIEKSGLIDKIDGFITTDSPLAKLRY
SSILASIKTQTFFNKPSIATISMRDRNSFALQADLIGANDFNLRCFLALTGDGVNHGDQP
QAKGVFEQNSLFLLQIINALNSQKDIANNPLKEPLKPIYGFCVLNSYSKKLESLKRKMAK
KIETGCIAIVTQPVYDLDVANMLHDWLVELTSKYSDFRKDTKLIFGFFPVVSYKGAYFLY
SKLPGVFIPDSWLERLEIASKISKDEEFKVGFEMSQKLLETIYSTHQKLHLMSSNNAKLM
KDLIEGVA
>A0A1I4EY09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porphyromonadaceae bacterium KH3CP3RA|TrEMBL
MRVSELINNTGKTAFSFELLPPLKGNSIQQVYNAIDRLKEFDPKYINITTHHSESIYKED
ENGTYRKVNVRRRPGSVAIAAAIQNKYGIRAVPHIISQGFSKEETEYALIDLSFLGVTDL
LLLRGDTKKLDAEQRKMDCHPYATGLQEQVNNFNKGITFDGSSFTPPEELFSYGMACYPE
KHEESPNMESEIYYTKMKVDNGAEYLVTQMFFDNSKYFDFVKRCRDVGITVPIIPGIKPI
HMKNQLTVLPRIFRTDIPEELATALRKCRNDEEAKEVGVEWCIEQCKELIRNNVLSIHFY
SLMATESVRRVAGEIY
>A0A5D0UKK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura syzygii|TrEMBL
MAFEIVCEVEPPMKPDLTRVRHQIGVLSPVADSFLIPDNHIGRATVSSVAVAHEVQAMGA
RGIACLNSRDRNLLGFRRDLLTAAAYGVDRFLFVYGDKPSIGGRTSELTVRAMMDETRAA
AEDAVFAGCAPFQIGVTTGLRKTPEWKRSADFTFVQVSYSVDDLLRWRDDARLNGPVYAG
VMVLASAGMARNLAAAIPDIAIPAELVDAVERDRAAGVAVACEQVLAIRDSGAFDGVHLV
PVSRYREVAARLEREL
>A0A174WB67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Ruminococcus] torques|TrEMBL
MKIIDKLNQKGIHISFEVFPPKTDAGFDKVLSATDEIAKLNPSYISVTYGAGGGTSKNTA
KIASHIKDDLGVMSLAHLTCASSTKEEVGEVIENLKAHGIENILALRGDIPEGMTFPDGD
RFHYAYELVQEIKKHGDFCIGAACYPEGHVEQEHKEDDIRYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITSAAQMKRSQELSGTVFPRRFLAILDRFGSSPE
AMKQAGIAYATDQIIDLLANGVNNIHIYSMNKPEIAVAIMNNLSEIIKC
>A0A4U0PPA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitiniphilus eburneus|TrEMBL
MTRPPISFEFFPPKTPEGVEKLRNTRRQLAQFKPEFFSVTFGAGGTTQDGTRSAVLEIQQ
EGFAAAPHLSCIGSTREAVAALLTDYRANGIRRLVALRGDIPSGMVDVGEFRYASELISF
IRAEHGNWFHIEAAAYPEYHPQAPSAEADLRNFVTKVNAGANAAITQYFFNADAYFRFVD
EVRGRGVTIPIYPGIMPIQNFTQLSRFSEMCGAEIPRWLRLRLASFGDDSAAIRAYGLDV
VTELSDKLLAGGAPGLHFYTLNAAGAVSTVCQRLGF
>I0HLF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax gelatinosus (strain NBRC 100245 / IL144)|TrEMBL
MSTTPVSFEFFPPNTPVGADKLRTVVQDLAAVKPEFFSVTYGAGGTTRERTLETVKAIAA
MGHEAAPHLSCVGSTEANIAEILATYRQQGIRRIVALRGDLPSGTATAGEFRYASELVEF
IRRTQGDDWFIEVAAYPEYHPQQRYARRDLEHFAHKVRAGANSAITQFFFNPDAYFHFVD
EVHKLGVRVPIVPGIMPIHNYARIAQFAARDGIEIPRWVALKMEGFMDDAASVRAFGVEV
VTRLCERLIAGGAPALHFYTLNQSALSLEICRKLGLAQAD
>A0A1N6RFM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. TND4EK4|TrEMBL
MNAFRPSRHGSRRPSVSFEFFPPKSEEMEVALWESVRRLEPLGPSFVSVTYGAGGSTRER
THATVKRMVEETQLKPAAHLTCVSASKAEVDEVIRAYWDAGVRHVVALRGDPAGGLGTVY
EPHPEGYHQTCDLVAGLKRIGDFEVTVSAYPEKHPEAASLDADIEALKMKVDAGATRAIT
QFFFDNDVYFRYLDKVRAAGIDIPILPGIVPVQNFKQTANFARKTGASVPQWLADRFEGL
EEDVATRRLVAAAVCAEQVLDLIDRGVADLHFYTMNKADLVYAICHLVGLKPEKAAAQAV
AAE
>A0A4R8VJK8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium levicorallinum|TrEMBL
MSACNARPAFSFEVYPPKSAAAASALMSTIDHLAAAGPEFISVTYGANGSSRNSSLDLLR
YIKDHTEADAMAHLTCVGSSHAGASRLIREFLDAGIRSFLAIRGDAPQGAVEGDNTFLGD
LHSAGELVQLIHRVQTERVPYIETVIPGLPGARGVKTERSKVRIGVAAFPNGHPNSRSVS
QDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLFPILPGIMPVTSPNRLRRI
LQLSGEKLPADLSIDLEVEPTEEGQRQIGIDYAVRLGQDVLAGGAPGLHLYAFNQHDTVL
QVLEGCGALPVPAVML
>A0A379JMJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia otitidiscaviarum|TrEMBL
MYSPSESGLSGVRRPARISPIASGVPSVVQSLRRHAAGPRVPFSVEFNPPRDAAGEARLW
RAVREFERMHPAFVSMTYGAGGSTKDRTARITGQLAQQTTLLPVAHLTAVGHSVAELRAL
VGSYADCGIRNILVLRGDPPGDPLGEWHRHPDGVEYAEELVRIVRDLGDFHVGVASFPQG
HHRSPDLDTDTAFLAAKLRAGADYSITQMFFDVEHYLRLRDRVLAADPVQGAKPIIPELM
PITSMRTVARAEELSGRALPAAVLDRLRRAAGDGPEENRAAVRRVGIEIATEMAQRLIDE
GAPCLHFITLNFAKATTEVLTNLGYEVTAAPLSA
>A0A5P3KJ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas arboricola pv. pruni|TrEMBL
MTHLSFEFYPPKTDDQRAQLDRTAARLRGYAPEYVSCTFGAGGSTLSYTSETVRHLKQKH
GFDAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYASDLIAFI
RAEHGDAFRIEVGAYPETHPQATDALSDLRYFKAKVDAGADAAITQYFYNADAYFHFRDA
VQRMGVEIPIIPGIMPISNFSQLRRFSEQCGAEIPRWISKKMQSYGDDADAVRAFGAEVV
ATVCERLIAGGAPALHFYTLNLAKPTTQVLQLLGR
>A0A1Y0D4M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanisphaera profunda|TrEMBL
MGFHSARHVDALNQTMAELGSNINVSFEFFPPNSEKMEKTLWDSIERLSTLAPKFVSVTY
GANSGTRDRTHKVIKDIQEKTGLIAVPHLTCIDASRAELRDIAKDYWNSGIRSIVALRGD
LPEGLEKPDMYAEDLVRLLKEEADFDISVAAYPEVHPEAKSAQADLLSLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVTIGIDTEIVPGILPVSNYQTLIKFAGFSNVRIPNWMHQRFQ
GLENDQNTRNLVGASIAMDQVRVLSQEGVKDFHFYTLNRSDLTYAICHSLGVRPQISIPA
>A0A367XWJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candida viswanathii|TrEMBL
MKISEKLDHAHRAANSPPATFSFEFFVPKTSQGVQNLYDRMDRMYDLNPIFIDITWNAGG
RSSSLTNEMVYTAQSTLGLETCMHLTCTNMKVELIDEALDKAYKSGCQNILALRGDPPLD
GSESTGDFKYAKDLIAYIHKKYGDHFNIGVAGYPEGHPEETDEVKTLEYLKEKCDAGADF
IITQMFYDVDNFISWCSKLRKIGIDLPIIPGIMPISTYSAFLRRAKWSEISIPQHFLDAL
DPIKDDDFLVREKGTELVSEMCQKLLESGYVNHLHFYTMNLEKATVMILERLNLVEAVKS
NEIVGVTELPWRKSLNPERSKESIRPIFWQNRKYSYVTRTATWDEFPNGRWGDSRSPAFG
DIDLCASELLRQSPKRAQELWGLPQTVQDITLLVISYLKGNLKSLPWFDGAIGDDTNIIL
DNLIELNENSLITLNSQPSLNSVRSSDKVFGWGPKNGYVYQKQYLEFFCHKDVVAKLLDH
IEKYNHQQGDSTSAVISYYAVNKDGNLISNCQDDDINAVTWGVFPGEEILQPTIVEKTSF
LAWKDEVYTLFSEWLKVAAMFDADKAKVQEFNKLMGQISEDFVLCNLVNNDFLQGNEVLF
DLIKQVVHT
>A0A4R9GER1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira selangorensis|TrEMBL
MKKILEIYKTAKTPVYSFEFFPPKTPEGEVKLFEAVGELSKVDPGYITVTYGAGGSTREK
TIRITSELAKKFSLPAAAHFTCVGGNKEEIKVILKQIRESGIENLMALRGDPPKGEEAFK
KVEGGFGYASELISFIKQEGFDFCMGAACYPEKHPEAASLESDVDNLKRKVDSGASYLVS
QLFFKNSNFESFLNLIRKKGINVPVIPGIMPITSFTQIERFKAMAACEFPEKLVSDLEEV
KDQPQEFYKRSVNFSVNQCRELLKMGAPGIHLYTLNQSPASLDIVRELKN
>X6D2Z7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LNHC232B00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDHILHDEITETQVDMVK
TAH
>A0A5B0X5U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photorhabdus heterorhabditis|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTVEMEKTLWKSIGRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLEAAPHLTCIDASRDELRKIARDYWDNGIRHIVALRGD
LPDNSEKPKMYGVDLVELLKEEADFDISVAAYPEVHPEAKSSQADLISLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFRQLRRFAAMTNVRIPSWMTRMFD
GLDDDPESSNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A328MA96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. SRB_331|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGVDAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0F3G263|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas oleovorans|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRTETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDADSIRVFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLPR
>A0A836WV28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospinaceae bacterium|TrEMBL
MKIIEKLNGSSPIFSFEFFPPKDSDGFATLFETIARLKPSAPAYVSVTYGAGGSTRAKTV
DLVGKIKNDIGIESMAHLTCVGHDEQEIRSVLESLQGQDIENVLALRGDPPQGEETFVKT
EGGFEYASELVSFIKNNFSFCIGAASYPEGHVECPDLDKDIENLQRKVDSGVDFLITQLF
FDNRYYFDFLDKVQKKNINVPMIPGIMPILNLKQIKRFTKMCGAHLSDSLMAKFEGVQDD
NEKVRQIGIEHAIAQCKELLENKVPGIHFYTLNRSKAT
>A0A120A123|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides cellulosilyticus|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYDTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNRYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQITMIPKTFKVDLPEELAYEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHF
YSIGAVDSIKEVAKLVY
>E8UZC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4)|TrEMBL
MKNVAADWLKSRTLLFDGAMGTMFYARGIFINRCYDELNLTEPEMVRELHEEYLMAGAEA
IETNTFGATAPRLARYGLAEKVGAINRAAVVIAHRAVRHAKEKLAVDALVAGSIGPVADA
ALSEDEVRNAYREQMAALVEGEGIDLFAIETVMSLREARLALEAAALAAPGIPSIVMVTV
NEVGQCLDGTEVEEAVRFLEAAGAAAVGCNCSSGPEMILRTIERMRAVTTLPIAGMPNAG
VPSCVDGRSIYLTSPEYMASFARKALRAGATIVGGCCGTTPAHIRSMRGALRAVVAQQEG
TASAGKGTKSDHAVAIVEPMPLAARSLLGGRIARKEFVTMVEIVPPKGIDASRELEGARM
LHAMGVHAINVPDSPRASARMSAGALCIQIQQKIGVEVVLHSTCRDRNLLGLQSDLLGAA
SLGLKNMLCLTGDPPKMGTYPDATAVFDVDAIGQLAMAREMNRGFDIGGNSIGASTNFVL
ACAANPGLPDLDAEVRRFAAKVEAGAEFAITQPVFDLRLLEDFLRRIEQFRIPVIAGIWP
LTSVRNAEFMRNDLKVSVPESIMTRMAACETPESAREEGILIAQEMLREARPQVQGVQVS
APFGKYELAAKVLDGFLSGGGNGDV
>A0A7K1JWG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides sp. CBMA 271|TrEMBL
MTTNPLDRAGPVAELQDPGSIADRLAAAAPGEVAFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAESTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPVGDVNAEWVPHPGGLTYAEELVRLVRDLGDFHVGVASFPEGHPQAIDLE
RDTAHLVNKLRAGAEYSITQMFFDVDDYLRLRDRVVAADPEQGAKPIVPGLMPITSLRSV
RRQVELSSSTLPPALEERLLRAAGDGPEENRDEVRKVGVEVTTRMASRLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTVRA
>T2F4Z3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris KW2|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYIDKTQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHHLKEKVDSGADKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>A0A366WGZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. F3R11|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQVVRDQLAGVNPDFFSVTFGAGGSTRDRTIETV
LNLHKQGISTAPHLSCVGGTREEIAELLDLYKENGINRIVALRGDMPSGMGASGEMRYAN
ELVEFIRQHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVEAGANSAITQYFFNPESY
FYFIDRLEKMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDSVSIRK
FGEEVITRMCEKLLEAGAPGLHFYTLNQAEPSISIWKNLGISEREKIAF
>A0A1F3DMH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWA2_40_15|TrEMBL
MTVIELINNSKRPLFTFELLPPLKGHSIERTYTAIDRLIEYEPAYINFTSHRNETIYKER
PDGLLEKKVVRLRPGTIALAAAVKYKYNITVVPHILCGGFTKEETENVLIEMRFLGIDDV
LALRGDPQKGARSFIPEKNGHVHTTDLVNQIADMNRGKYLEENLENADLTHFCIGVAGYP
EKHFEAPNRHVDLENLRKKVEAGASYIVTQMFFDNNKFCRFRDECRKIGITVPIIPGIKP
ISALHDIKLLPQTFHIDLPNDLFSAVSKCKTDTEAREAGIEWATTQSKELLKLGVPGIHY
YTLGRSDNIARIVKATF
>A0A2W5EIG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium fabrum|TrEMBL
MRSETARHNGEIRGDIRLSFEFFPPKNAEMETQLWETVAELKKWDPDFVSVTYGAGGSTK
APTLDAVRRMIGDSHLPTAAHLTCVDASRDDVHQVIEEFRNVGVRHFVALRGDPSTGIGT
AYKPHPEGYENAAALVKGLRDIGDFEISVSAYPEKHPESASEAVDIDMLKRKADNGATRA
LTQFFFDNDVFERYMERVTAAGITIPVVPGIMPIQNLHQLKRFAGRCGTSIPGFLDERFE
GYDEDLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A0D2E2Z5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phialophora americana|TrEMBL
MASGHDDRLPTLFSSLDPSSYYFSLEFFPPKTSSGFSNLQSRLARMASALRPLFVTVTWG
AGGSTATKSLELAELCQRQLGLTTVLHLTCTNMKKDMVDEALEAAKEIGIRNILALRGDP
PREEYKDAVSTEEIEGGSGGGGTESNEEFTWAVDLVRYIRRKHGDYFAIGVAGYPEGHAD
ESHPEQGKQSVEHDLPYLVEKVSAGADFIMTQLSYDIDAYRKYEDRLRNYTDQGGERLFE
KIPIIPGLMPIQSYQIIKRITKLSHARLPEDISKRIEAVKSDDEAVKKVGVDVLSELVEQ
MKTLPQPAGVPRGFHFYTLNLEKSVAFILERTGLIPPVSSEGSTEDRDGDSSSDSDVVVV
DDKRDVSTLTMKGQTDQDARRTQVSAFSRRRKSSINAQPHNRVILDRLSRSPAQARPEGD
TDPPPRRSSNLAAQHSARDRGTGIPASSPTRRHHLLISEGQGSLGREATWDDYPNGRFGP
SHSPAFGEIDGYGPSLKVSPLMARKLWGHPKSSGDITAIFRQHVSGDLVGVPWSDDIDPS
GSGGAAPSKDSSGALRAETDVIRSELLSLISKQNYWTLASQPAVDGAPSSHPIFGWGPPG
EGFVFQKAFVEFFCSRDEWETRLKGRLQSYGSEVLSWMKTDAQGVFESARHGAEMTNGVS
KTNAAGTTTNPTSATIASARDSTVASDVNTVNAVTWGVFPSREILTPTIIEAESFRAWAQ
EAYAIWSEWKRCFPRGSEEATFLDRARGDVVLVNIVGQEFRGGHEGQGGRLWRILLGEDG
ERPASPTDAR
>A0A7W3XXP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces calidiresistens|TrEMBL
MALGLPSVRTDRARTVRELLAAGERSYSFEFAAPRTERGEQILWEAIRRVEAVGPTFVSV
TYGAGGTSRDGTIRATERITTETTLTPVAHLTAVNHSVAELRNIIGRYADAGIRNLLALR
GDPPGDPMGEWVRHPEGVTYASELVELIKDSGDFCVGVAAFPEMHPRSTDRETDIRHFIA
KCRAGADYAITQMFFRAEDYFRLRDRVAEAGCETPIIPEIMPVTSVKQIERFAELSNATF
PPELERRILAVADDPVAVRSIGIEYATALCAELMEQDIPGLHFITLNRSVATLDIYRNLG
LHRRSDR
>A0A8J7M9R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermohalobaculum xanthum|TrEMBL
MSGFEDHGDFVRPYEEPPPGHVSSSRLERVLRSGRFAVTAELNPPDSADPADVFEAARPL
GEVADAINATDASGANCHMSSIGISALLTRAGYGTVYQISCRDRNRIAIQGDVLGAAAMG
VRNVLCLTGDGVGVGDQPGAKPVFDFDSLSLLRTIRTMRDDGVFLSGRKISRPPRMFLGA
AENPCIEPHEWRPERLAKKVDAGAEFIQTNYIFDIPLFEKFMARVRDLGLDKRVFILAGV
GPLASAKAARWMRSNVPGIHIPDSVIARMEGAQKPGEEGKKLCIELIQRMREIPGVAGVH
VMAYRREHQVSEIILESGVLEGRRARRRGSEPTGAGPEA
>A0A655Q9H9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio cholerae|TrEMBL
MAAFPEVHPEAKSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVAAGIDVEIV
PGILPVSNFKQASRFAAQNNVKVPNWMVKQFEGLEDDPVTRQLVGASQAIDMVRVLCREG
VKDFHFYTLNRAEMTYALCHTLGVRPQA
>A0A4S3FL04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. Mn16-1_5|TrEMBL
METHNFSIEFFPPKTPEGAEKLRVTRRKLAELNPKYFSVTFGAGGSTQQGTLDTVLDIMA
DGHLAAPHLSCIGATRESIRAILKQFQEKGIRRLVALRGDLPSGYGGAGELRYANELVEF
IRAETGDWFHIEVAAYPEVHPQARSPQDDLLNFERKIKAGANSAITQYFYNADAYFQFVD
NAQKLGLDVPVVAGIMPITNYTQLMRFSEMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLAGGAPGLHFYSMNQAVATTAIWQRLVAK
>A0A1M3QCD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium 70-18|TrEMBL
MNSVVLSPTASSSAAPGRSTATLERWLTGPRFGGLPARHAGHAPPALSFEFFPPRTEALE
QQLWACIRRLEPLAPRFVSVTYGAGGSTQARTHATVARIVAETSLTPAAHLTCVGATREE
VDAVARGYWEAGVRHIVALRGDVPGGGAYEPHPGGYAYAADLVAGLKRVADFEISVAAYP
ETHPNAANPLADLDNLKRKLDAGATRAITNFFFDNSAFLRFLDLALAAGITAPIVPGIMP
VTNFAQQAKFAAMSGVSVPDWLGHMFDGIADDLETRRMVAAVVAAEQVRLLQANGIDEFH
FYTLNRSDLTYAIAHILGVRAKVASPTPA
>A0A2N2WSF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-5|TrEMBL
MTVIEKINNAKSPLFTFELLPPLKGHSIDKIYASIEGLLEFEPAYINFTSHRNETLYRER
ADGTLERRVARIRPGTIALAAAVKYKYNITVVPHLLCGGFTKEETENALIEMNFLGIHDV
LALRGDPVKGTRMFIPERDGHRNTNELIEQVVNLNKGRYLDSSMESASPTSFCIGVAGYP
EKHFEAPNLEVDMAYLKQKVDAGAHYIVTQMFFDNEKFYRFRDLCHKIGITVPIIPGIKP
ISALNDIKLLPQTFNIDVPQDLFKAVVKCKEDKEAREAGIEWATMQSKDLIKNGVPGIHF
YTLGRSDNVARIVKSSY
>A0A5P2AWN1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces venezuelae|TrEMBL
MALGTASVRSDRARTVREILASGGTSYSFEFYAPRTAKGEQVLWNAMRRVEAVGPSFVSV
TYGAGGTTRGGTVKATQKIASDTTLTPVAHLTAVDHSVAELRNVLGQYADAGIRNMLALR
GDPAGDPLGEWVEHPEGVLYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSVAKAGCETPIIPEVMPVVNVKTLDRLPQLSNAAF
PAHVKDRILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHQQS
>A0A4Q2W8J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium oxysporum f. sp. narcissi|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDRIKAIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLASPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVEKDALWQLLLS
>A0A0Q9CNH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oerskovia sp. Root918|TrEMBL
MSIVDLGHFGHEAPRPTVSFELMPPRRPDAAPKFWETARRLVATSPDFVSVTYGAAGTDR
ETSRRVISQLLHGTPVLPIAHLTCVGASREDVEDVITDFLDAGVRSFLALRGDPPRDQPD
WRPAEDGVRSSTELVALLREVEAARCAASPSVALRGAARPLTIAVATFPDGNLAAGTSRT
QEVRRLWQKQQAGADFAITQLFYEASSYIDFVAEARAAGVTIPILAGLLPMTDPARLARV
EELTGVPAPRRVVEALEAEPDPAARHALGIRHSVELARQVLAAGAPGLHIYTFNKHQAAL
DLLEGVDLGGGAAGDASGVSSRTPDLASGPWVSGTPLPSSEPALGSASV
>A0A3D0XCG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp|TrEMBL
MKISQLFKDTDKTVFSFEVFPPKKDSPIESVYSKLEEICSLKPDFISVTYGAGGTVGHSR
TAEIASKIKNDFGVESVAHLTCANSTKSDIDANLDDFVQCGIENILALRGDYVSGVEPKK
EFVYASDLCSYIKKKGDFDIAGACYPEVHIEAKDEVEDVLNLKNKVEAGAEHLISQLFFD
NSVFYRFLERTKIAGINVPIEAGIMPVTNKKQIERMVSMCGASLPAKFSKIMQKYEDKPE
ALRDAGIAYAVEQIVDLIANGVDGIHLYTMNNPYVARKITAAIANLL
>A0A1E7JCJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium C00003063|TrEMBL
MSFQKRLSANEFVVLAEMHTPKGVNISRLVNDARRMKGRIDAIVVPDMDNGIMRMSALAG
GVLMQQQGVEAIIHVYCRDRNRMALQGDMLAAYVLGVQNLLVTHSEDIEQSDHRDARQVY
DLDEVELVQVIATLNQGKDMGGFELDGVPEFTAGCTIAPYSDEKGLAGELEAAAKKIEAG
AGYIITPPVFDLDSFAGFMEKAKELNAPIIPTVFLLKSLAIAQYIARSEPGANISEDLIK
RIRKSSDRELEGIKIAGETVAALKDLSQGVMLQTLGWEHKLPEILDMAGL
>A0A8I0KUE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizorhabdus sp|TrEMBL
MASDHFLDDYSIEITAKDLGPLVDAVGVLPAGSAVSITFLPGNSVDQLVEVAAQVRRLGF
EPVPHISARRIASHDALDHFLAGLASRAQARRAFVIAGDPNTPIGPFADALAVLESGLLQ
AHGIRKVGIAGYPEGHPAIAPDTIWRALGDKVAAARDGGLDLQIVTQFVFDPDIIAAWVA
EVRTRGVSIPIRVGIPGPASVQALLRFAARCGVGASAKVMAKYGVSITRLLNTATPDLLI
RQLADRLVAADEAGVKAHLYPFGGVEKTARWAGQFAPRERE
>A0A7W3FWY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas sp. TW 6|TrEMBL
MGFHSARQVEALNQSLADLGGDISVSFEFFPPNSEGMENTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELRTIARDYWNSGIRHIVALRGD
LPPGLDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLNLKRKIDAGANRA
ITQFFFDVETYLRFRDRCAAIGIDAEIVPGILPVSNYQTLAKFAGFTNVKIPRWMHQRFE
GLENDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQA
>A0A2M4CST3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anopheles darlingi|TrEMBL
AEYKNKQSPVVAASLVRIAFTVAVRRYITSRSMSIAEEPAAFSLRGKLSHIFQPTSGEGA
SSSTRSVFYSIEIAAKDDFNIDQLRRLTPRPVFCSMPWISDENLRYEADFAQMPSLRLAD
QLRHEQFTVVNHLSCYNLSEAHVDKLLSSQPSIRNMFIVRGDTVNPGQRFLHSAQLVQYL
RQYESSRSATAAKLTIGVGGYPGGHVESPSQEDELRHLADKVALGADFLLTQTLYDAASF
FRYRDRCRAAGITIPIIPGIYLPHSYRQLQTMLNITRVAMSPTVRATFEEHRDDTPEAFE
AFVVQYFVELVRELLQSNAIEPGSSDSVGLIHFFTFNKFSLLEKVISQLEFA
>A0A5N9GJB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
LDGIKQMAAVSTKWLSAQPNAGFATYVGGRFVYRSPSDYMALQAKLMIESGAIIVGGCCG
TTPEHISKMRASIDTIDIQRRISGTKQFPLPAPTIPPAVISGNPATNFQDKLKSDFAVSV
EVLPPKGFNTMPTIENIKRLSATGMLHAVNIPDSPRATGRLSALVLSSIVRSKLSVEPIL
HLATRHRNLVALHSEILGAQAMDVRNIFVVMGDLPRIGDYPDATAVSDITATGLIHLLTQ
FNRGLDLASRVIDGKTSFHIGGAFNMSARDPDRELRLLKRKIEAGAHFILTQPVYDPDLV
EYWSDQLNPLKIPILMGLLPLRSSRHAEFLHNEVPGIVVPANIRSKLEKSGKAATTVGLT
LAKEMLELCYERFSGVYLLPSSDNFDTTLQLLEHLRTLKVRSGQLDVDVQNL
>A0A837J2H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliarcobacter butzleri L351|TrEMBL
MFKTLIQKLQEDKYLTLETTPQHEPSMHNIIEKIKKFNLQDKIDGFSCTDNPLAKLRYNS
LFAALKLQQEFEKPVIATMTMRDRNKIALQSDLLGANDFDVRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGHPFKIEPKQIFPFAVVNSYAKNFSSLEKKMHLKI
QNGAIGIITQPIFDIENAQKLLESFDIAKENVEGDKRKSQLIFGIFPVTKLRTALFLSAQ
VPGIHVPQFWIDALEKAHSIGEEEEYKVGMELSSNLFKELNKLHPKIHLMTANRFDVANE
IIS
>A0A8C5E114|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gouania willdenowi|TrEMBL
KCNNIKDNSGPDLFLGASGGDSSKESSRCSTPVLDADRSDRLRDKMRKRIESGDHWFSLE
FFPPRTASGAVNLISRKVTDCFTCLAYRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMM
IASTAVNYCGLESILHLTCCNQSKEKITAYLNKAKHLGLKNIMALRGDPVGSEWEDEEGG
FNYAIDLVKHIRSEFDDYFDICVAGYPTGHPEAETYEADILHLKEKVDAGADFVISQLFF
RADTFLKFVNDCRAIGIKCPIVPGVFPVQGYQSLRQLAKLSKLEVPEEITRVIEPIKDND
AAIRNFGIHQAVEMCRLLLDSGIVPGLHFYTLNREVATMEVLRQLGLWNEDPRRPLPWAM
SAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSK
SSKEALLQMWGEELMNEQSVYEIFTCYITAQSNPCGHKVLCLPWNDEPLAPETNLLKDEL
EKVNRRGVLTINSQPNINGKPSTDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKILKK
YEPRVNYHIVNVNGRNWTNANDMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALW
IEQWAKLYEDESPSRMIVKYIHDNYFLVNLVDNDFPLENCLWQVIDDMFELLSEAQELLS
DGAISE
>A0A5N9CZP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MATQDLRSMLEGSDRFLTAVEIETSRGLLMAETSRKTAELAKSLSEFDRVDFVALTDNPG
GNPHIRPEILGQDLVFRGRDVVINMSCKDYNRNGVESRLWALGSQGFTNVLALSGDYPTG
GFQGQAQPVFDIDSVGLLELIEQMNEGLPNRVWGSVGREDRLETTSFYAGCAVSPFKKLE
GELMTQYFKLAMKVRTGAKWAVTQIGYDSRKLGELQQYVQSTGINIPLIGSVFILTAPAG
RFFNNWGMPGVWVSDELRDIANEQARSKDRGRAFFSELAARQIAILKGLGYRGAYISGRP
QLERIQHILEMVDSYGENDWKEFAKEIKFAQDDEFYYFEQGDHPGLSSDAVNKEYLASKS
RSKLGRARARMTVPLQYRLGKFVHDRVFTEGTLGFKAGSAIYGQVEKSKKLTAVAHVLEQ
ASKVPVYHCRDCGDCSLPDVAYLCPESECVKNQRNGPCGGTKAGMCEVLDKECIWLRAYD
RLKPFGQEEKMLERPVVFRDASLRNTSAWANTFLLRDHHAKRNPADRLGGA
>A0A8H6S9R2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycena indigotica|TrEMBL
MKLSDKLNSLRSSHPFFTLEFFPPRTDQGFENLLPRIARLSTLAPLAVSITWGAGGSTKE
RSLDLAGITQGEYGLDTILHLTCTNMAQGMIDQTLKAAKERGITNILALRGDPPRGEEEW
TPIDPRFKHGADLVKYIRSIPEYAAHFCIGVAAYPDGHTGQLDDERAEIEYLKLKVDAGA
DFIITQLFYDVDSYFQWESKVRAAGITVPIIPGIMPIQTYASFLRLTKLTGAHVPDSVMQ
ALEPICNDDQLVKEYGVTLATDMIQRLTEEGRVPGVHISTLNLEKSVQRVLEGLKWTSSP
SSPLMAQNKLIDEIPRIDDLSITASTAASSATFGLANLPAAVESEAGRGELNNASSWDDF
PNGRFGDFKSPAFGSTDMWGGPAIRPVDVLQHCGHPRTHADLTSIFLAHLHSRIPITPFS
PTPLSPESLSILPHLERLTEAGWWTVGSQPAVDGARSDDEVVGWGPRAGHVFQKGFVEFF
CTEAEVDRIEHRAQQKGLGWVHWFAGNKHGECRGNVPEGGRNAVTWGVFPGQEIVQTTII
ERESFLTWKEEAFSIWADWASLYRPGSVERRLLESVGDDRWLVSIVHHDYRNSSALWTFV
FDEGEP
>A0A080N201|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bombi DSM 19703|TrEMBL
MHSPIFSLEVFPPNTRTSVNTIYDTMDGLKEVEPDFVSVTYGHGAFKDRTRTACIAATIH
NEYGFPVVAHLTALYSDEAIVDQALQYFHEAKVAGVLALRGDPVEGNEPCGVFEHASDLV
AYIRSKEPGMPVFGACYPEGHVECSCLEEDIANLKRKVDAGATHLLSQLFYKNDDFYRFL
DLARGSGIEVPIEAGIMPVVNVRNVETMNQRNSTSIAPALQRMIDRWGSDPKALRQAGVV
YASEQIADLVAHGVDGVHLYTMNRPSVARSIWQNVEGLFGRA
>A0A3T0CWK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. NP-4(2019)|TrEMBL
MKLAYQRQTGNAEDPRTIALVQELVCNATIEATPRQILEIDSLTELFPAGTWVYVPFLPH
GQFSETLPACQRLIDEGMLPVPHLPARLVESHDQLRDWLGQLREIGVDRLMLIAGDSDSV
AGPFPDTLALLESGLLEQQQFLHIGVAGHPDGHPVAGPDSLARALSLKRDYARVTGTRLW
VVTQFAFEAERYTGWLQAVGDILPEVPVYMGVAGPTNLKTLIAYAAQCGVGVSARTMWRK
PGSARLLRSWTPDGLVHALARHRQDFPDTLLAGIHLFPFGGLQRSARWIRQCGEPDEPDE
VRGNLSDPVSDSV
>A0A1G3PHG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetes bacterium GWF1_51_8|TrEMBL
MKIRDILRQETGVAFEFFPPKNEASELSLFEHLKVLEGIDPAYVSVTYGAGGSSRANTSR
IVRRIAEEEKLTVMAHLTCVGHTRAEIETIVAEYHESGIENIMALRGDTPRGTNINPADG
ELPHAIDLVRLIRKIYGDGFSIGIAAFPEKHLESPDWDCEISRFKEKVDAGVDFAVTQMY
FDNEFFYRYIERARKAGIAIPIIPGIMPLTNYKQIETFNTLSGAVMPKELIGAVEKAAGD
EQAVYKIGVDFAVRQCLDLIAHGHKFLHFFTLNKSNASLDIYNAIRSSLQ
>V4NLV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Asticcacaulis sp. AC402|TrEMBL
MSPALNPKLSPIARSLSQTSGHMRVSFEFFPPKNEEMESTLWTSIARLAPLDPDFVSVTY
GAGGSTRERTHRTVKRILDETRLKPAAHLTCVEASRDEVDEVIHAYWDAGVRHIVALRGD
PPSGWGDYAPRADGYQNATELTAAIRRIGDFEVSIGVYPEKHPQSPSRDFDLDVLRAKVD
AGATRGISQFFFEPETYLRYRDAVFDAGIDIVLTPGIMPVTNFKGLRRMAAACEAQVPQW
LESLFDGLDDDAETRKLLASAVAVELCLELEREGVENFHFYTLNRADLVFAICRILGLKA
ATQ
>A0A351V413|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium|TrEMBL
MQTQQKYPKLFSFEFYPPKTEAGEESLQAVHEKLSRLNPDFFSVTFGAGGSTRDKTFDTV
VKIQERGVAAAPHLSCVASTHENIREILHGYRSNGIKKIVALRGDLPSGMMSAGQFRYAN
ELVDFIRSETGDYFQIHVAAYPETHPQARSAAEDLKNFKRKVDAGANAAITQYFYNAESY
FYFVDACEKMGIDIPIVPGIMPITNYSQLFRFSDMCGADIPRWLRKKLEGFGDDKEQIIA
FGCDVVTRLCQQLLDNGAPGLHFYTMNQSAPTLAIWNNLNLSD
>A0A0P8AMZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HLUCCA01|TrEMBL
MKVTEHYDRATEPLISFEIIPPRRGASIQNVFDALDRVKKFNPPFIDITSHAAEAEYIDL
GNGTMKRRVKRKRPGTIGLCAAIKHRYNVDPVPHLICKGFTKEETEDALIELHYLGIDNV
LAVRGDDHGAPKPHHKDRAVNTYASDLVRQVKDMNKGIYLEDLMEASHTDFCVGVGGYPE
KHNEAPNLVWDIKRLKDKVAAGADYIVTQMFFDNQVFFEFVDKCRAEGITIPIIPGLKVL
TRANHLVTLPKAFHLSIPCDLSDAVAADPESTSSIGQEWARKQCLELLDHGVPGLHFYIM
SDPSPAINVIESLPLGQSNVV
>A0A1B1BHS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium arcticum|TrEMBL
MSAAVASTGADPACPPSTPFSFELYPPKTDAATTALHSTIDTLAAAGPEFISVTYGASGS
SRTSSLDVLRYIRTATRVDPMAHLTCVGSSHAQASSLIREFLDAGVRSFLALRGDPPAGS
TEGDAFLGDLHSAGELVQLIHRVQAERVPYQETPIPGLPQARAVKTEREHVRIAVAAFPN
GHPRSRSTAQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPV
TSPGRLRRILELSGEELPAELSIQLEVEPTAQGQREIGISHAAALAKKLIAGGAPGLHLY
AFNQHETVLAVLDRAGALAPAAPLATSQLPPPTIAPTSPAAGTPAGTHPTKDS
>Q54X84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dictyostelium discoideum|TrEMBL
MTSMKIIDKIQKKKESNTPFYSFEYFPPKTMEGVQNLYDRLGRMLLFEPLFIDITWGAGG
STSALTLEIAEKAQNVCGLETMMHLTCTNMPVSEIIYALDKAKSTGIRNILALRGDPPRG
EEWKKIEGGFAYAADLVRFIREKYGDYFCISVAGYPEGHSDCVSKEEDIRYLKEKVDAGA
DFIITQLFYDCDIFCEFVEKCRSVGINCPIIPGIMPIQTYAGFVRMTTLSKTKVPQYIMD
NLEPIKDNDEEVKKYGVRLCVEMSKRLLDFGVEGLHFYTLNLERSVRKVLKGLQLVTPDQ
LSPFLPWAQSAAGNRLKEEVRPIFWQNRPRSYIARTGSWDEFPNGRWGDYRSPAFGDLSD
YHLGGVTPPPGGSANNNTTTTTTGDSVVVPNIYGDSPQSEQDVYNVFASYCSGNIKRLPW
NDSPLSLESENIKEQLVFLNKNGFLTINSQPAINGLPSTDKQHGWGGKNGIVYKKAYIEF
FASPENTLKLIEYFKKCPMITYHAVNRKGDSKTNTKGTNAVTWGIFPGKEIIQPTVVDHN
SFMVWKDEAFALWETQWSSTYSPSSTSRTLLDSMINNYYLINIVDNNFINGNIFQSFTDL
VNNLSSPVLSSSSNGIQSSTTSNTASI
>A0A5N9EBR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MHRFIQRIPSQTARVARISDRPATNSRGAPVVKITEGCFEATGHTSIICDFSPPRSGDSA
VVTQAQIDADFILVAYNPGRAVRTNSAMLAAAIQQSGKDAVFTLATRDMNKLAVQSLLLG
AQLLGLQNVVVVQGDLFGEQDRARVATVNDYHSTGLISAIVQMNQGQDFKEAKLRTPSDF
CIGGAVDLGRGIEEEAQLAVRKVQAGAEFLITQPIFNVDHVARYRESYAYHAGKSGTLPI
YFGLQILEQDGVLFSSVPESVRADLEGGRSGVDIALELYQEFQKARLNNVYLMPPIKRGG
ARNYEAAKEFLTLINKI
>A0A225ZZ47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus neoformans var. grubii c45|TrEMBL
MPHLTSLIAAHNGPFHNYEFFPPLTDPGFVNLLDRIRRLTSPPFQAPLAVSVTWGAGGST
AEKSLELAQQVVGMGVEVILHLTCTNMPKDKVDFALRRCKDLGISNILALRGDPPREEEY
AINPTSTPDFFKHADDLVRYIRQTHGDYFCIGVAGYPNPHPDSESEEEDFKWFKAKCDAG
ADFIVTQLFYDVDVFLEWVKTCRAKGINQPIIPGIMPIQNYASFRRLVNLTKCPVPDSIT
SDLQPISSDDATVKRYGAELATKMVNQIIGSGLVPGVHFCTLNLEKSVRKILDNLGWSAA
SKASENEGVVKNKLIEDDSRAVNGIPINGKADTAQSPAKNLSISPSEANQLAQLGLTSTT
LPPAPKTGLGAQGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKEWGVP
VSTSDLSALFTAYLHSDPKHLTTPFCDLPLSPESHMILPHLLALNSAKVQHWTVGSQPAV
DAARSEDEIVGWGPRGGYVFQKAFVEFFVTENEVNRLKEKVKKEGKGLITMYAADRKGDF
KSNTDKDSVNAVTWGVFPGQEIAQSTIIEETSFLAWKEEAFDIWTEWSLLYPRNTPSRKL
LEGIANEWWLVSLIHHDYKDQDALWRFLLEDLQ
>A0A5N9FKZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MHRFIQRIPSQTARVAWISDRPATNSRGAPVVKITEGCFEATGHTSIICDFSPPRSGDSA
VVTQAQIDADFISVAYNPGRAVRTNSAMLAAAIQQSGKDAVFTLATRDMNKLAVQSLLLG
AQLLGLQNVVVVQGDLFGEQDQARVATVNDYHSTGLISAIVQMNQGQDFKEAELRAPSDF
CIGGAVDLGRGIEEEAQLAVRKVQAGAEFLITQPIFNVDHVARYRESYAYHAGKAGTLPI
YFGLQILEQDGVLFSSVPESVRADLEGGRSGVDIALELYQEFQKARLNNVYLMPPIKRGG
ARNYEAAKEFLTLINKI
>A0A1B8QUV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus sp. CCUG 66565|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKAIKQETGLEAAPHLTGIDATPEELKQIAKDYWNSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVNAYEGL
DDDQTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRPS
>A0A3P3FC88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium tamadayense|TrEMBL
MIARQLDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAINPFAPPYDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYHEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVANRLDHILHDEITETQVDMVK
TAH
>A0A5N9AP59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium|TrEMBL
MNMISQLHRTLDSGSFAVTAELTLPDSSEKDELVETALKLSPYCDALNVTDATSAIPHFS
SLAAAYILLDNEIEPVMQISARDRNRIAIQGDVLGAHSLGVRNIFCITGDGVEAGDHPDA
KPVFDLDSISMLAALNNMDKTGSFMSGRKITPKPRLFLGAAVNPFAPPHSYRPHRTIKKW
KAGASFFQTQFCFDIGAMKRFSEKLVELSDGNPPPVLVGLGPLKSSKMAKWLRDNIAGVS
IPDRIIERMDHYPEKEQAQIGLEISKEAIDDLKSIQGVAGIHIMAYRWEEAVKELVEDSG
LSKINRL
>A0A4S5JCQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. MPMI2T|TrEMBL
MATRTLYPAERGNLRLSFEYFPPKTDEMEAQLFQTAADLSVFGPTFVTVTYGAGGSTKAR
SLTTVKRMIGEMGIGNTAAHLTCVGAPKAEVDAVIEEFLAFGVRHFVALRGDPQGGIGSA
YQPFPGGYENAAALVKALRARGDFEISVSAYPEKHPESPDVDADIDMLKRKVDNGATRAI
TQFFFDNDDFERYLERVRRAGVQVPIVPGILPINNLAQVQKFAGLCGARVPEVIHSRLAH
LEDQPSERFKEATHIAAEQIVDLARRGVRDFHLYTMNRSPLVTAVCDLVGYARVPAQEAA
AELPIRAVASA
>A0A8E1WA70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter lissarensis|TrEMBL
MNQFPLSRRSDIGNKIRVSFEFFPPKNDDMEARLWETVTRLEPLRPQFVSVTYGAGGSTR
ERTARTVKRILQESTLTPAAHMTCVDATREEVDQVIAEFAAMGVKRFVALRGDPKEGVGA
AYQPHPGGYANGAELVGALKAQGDFDISVSAYPEKHPESPDFATDFDMLKRKVDQGATRA
VTQFFFDNDLYERYVERARKAGIYIPIVPGILPIHSFGQVANFASRCGAHVPGWLAERFE
GLDKDPQTHALVASAVAVEQVLDLVERGVGDFHFYTMNRADLVVAVCHMIGIRPQPLVQG
AAAA
>A0A8J5HPK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zingiber officinale|TrEMBL
MEKNMKTYVCFACKQASSAGSIVDCKGIRILAMASLFIVVFVHVYRTTAESEMHPMKKKL
NVHLFTKVTRCLRLPQKTYMDTLTFGAPSIKVLDFEFPVVCMETIMHLTCMNMPVEKIDH
ALNTIKVNGIQNVLAFKGDPPHGQDKFVQVAGGFACALDLVQHIRAKYGDYFGITVAGYP
KAHPDMIQGDEGATLEAYNSDLAYLKRKTLSVVLKFWKSFSHVKILELCEIFILWSAIRE
A
>A0A520JZN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methanophagales archaeon ANME-1-THS|TrEMBL
MPKGEVYSQLMKEISEGKYVFTGELEPEKAGDVDEQIHAAKELVGLVTACNVTDNPQSFA
YVSSLAAAYKIQKESGMECVYQLRCADRNRMALLSDLLGASVLGIKNVLALAGDHVSLGD
TPDTKPVFDLDSTTLIYMIRKMVDEGKDLVGKEIHNPPKLHVGGAAAPGAAHLKAEVAKV
KRKIKVGVEYIQTQVVYYPEVLDKFFKELGKVDVPILVGIFPAKSFGAADFFDKYVAGVD
VPPDYLKSLEATKDIKDKEKKKDEIDRINVEYFTNFLEYLKGTPAAGCHMMAVGYPRIIG
PLRKVMK
>A0A359F9P8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionibacteriaceae bacterium|TrEMBL
MQATLPTIPEMLAAAKGRPLLSFEFSPPKDDAGQDLLHATILELDQLNPDFVSVTYGASG
STRDRTLGATQFIKKRVGPQTIGHLTCASQSSDDLRDVVRGYAEVGVNHVLAIRGDMPGG
PKAPWVRHPEGLDNATELVRLVKEVDPAFVVGVAAFPDGHPDKHDLALDARLMLAKQEAG
AEFAITQLFFDPAAYVRLRSTLDAIGCTLPVIAGVMPVTSLGQIERLAEMSGAPLPEAMV
ARLQAVGDDPQAVR
>A0A4V3SVI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. RKND-216|TrEMBL
MALGTASVRTDRAPTIRDLLASGRRSYSFEFFAPKTAKGERTLWDALRRIEAVSPTFVSV
TYGAGGTSREGTVRSTERIANETTLTPVAHLTAVNHSRAELRHVMGCYADAGIRNVLALR
GDPPGDPMGEWVRHPEGVSYAAELVELIKEAGDFCVGVAAFPEMHPRSTDWDTDVRHFVN
KCRAGADYAITQMFFRAEDYLRLRDSVTAAGCETPIIPEIMPVTNVRQIERFSQLSNATF
PPELADRILAVQDDPAAVRSIGIEYATELCARLQAEDVPGLHFITLNHSTATLEIHQNLG
LH
>A0A1H8WBI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinihabitans flavidus|TrEMBL
MTGPFADHPISVSFELFPPKTDKGEKSLARNVDRLATAAPDYFSVTYGAGGSTRDRTARV
VDMVRRRTGQPVAHHLTCVGASRKEIDAQAARLLEGGITRIVALRGDLPDGQTLAADGYA
DAAELVAGLRRVGDFDISVAAYPEVHPEAASPQADLDHLKRKIDAGANRAITQYTFDTDV
ILRFIDRARAGGISAPIVPGIMPVANFAGLKAFSAKCGASVPDWVARMFEGLDDAPDTRA
MVATSVATEQCRRLMAEGVSEFHFYTLNRPEVTLAICRALGLSPEIPAETAA
>A0A354TZD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonadaceae bacterium|TrEMBL
MSLQHAPKDIHVSFEFFPPKSEKAEDTLWESVRRLEPVHPKFVSVTYGAGGSTRDRTHRT
VKRMVEETDLTPAAHLTCVSASKDEVMGVVDDYLDAGVRHIVALRGDPPEGMGAK
>A0A1H8TQD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinihabitans flavidus|TrEMBL
MPAPSISFEFFPPQNLQASFRLWDTVQVLAPLNPRFVSVTYGAGGTTRDLTRDAVATLHK
SSGLNVAAHLTCVNASRDETLAIADEFAKSGVKEIVALRGDPPKGSDHFTPHPDGFANSC
ELISALADTGKFTIRVGAYPDKHPEAADMQADIDWLKAKIDAGADEAVTQFFFEADSFLR
FRDACAKAGINAPITPGIFPIENWTGARKFASKCGAYIPAWLDDAFDKALRDDRADLLAT
AICTELCSDLIDEGVDALHFYTLNRPELTRDVCFALGIKPEIKLENVA
>A0A1J0SUW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas mediterranea|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEKTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASREELKQIAKDYWDSGIRRIVALRGDLP
PGLEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTSVYLRFRDRAAAAGVDIDLVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSSA
>A0A495MP29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium endophyticum|TrEMBL
MKVTEHIEKANGKSLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEYKE
LPSGLLEKKIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIQN
VVALRGDAVKNETYFKPEKEGNHYATELVTQISNLNNGIYLDDELQNSSATNFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGASYIITQMFFDNKKFFDFVAKCRKEGITVPIIPGLK
PISTKKQLNLVPHRFKVDIPDELIMSIVRASDSEAVKQIGIEWCINQSKELIKEGIPVLH
YYSMGKAENIKAIAREVF
>A0A165QWJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactiplantibacillus plantarum|TrEMBL
MKFKQALQQRVLVADGAMGTLLYGNYGINSAFENLNLTHPDTILRVHRSYIRAGADIIQT
NTYAANRLKLTRYDLQDQVTTINQAAVKIAATAREHADHPVYILGTIGGLAGDTDATVQR
ATPATIAANVTEQLTALLATNQLDGILLETYYDLPELLAALKIVKAHTDLPVITNVSMLA
PGVLRNGTSFTDAIVQLNAAGADVIGTNCRLGPYYLAQSFENLAIPANVKLAVYPNAGLP
GTDQDGAVVYDGEPSYFEEYAERFRQLGLNIIGGCCGTTPLHTSATVRGLSNRSIVAHDQ
PATKPQPPTLVTTKSQHRFLQKVATQKTALVELDPPRDFDTTKFFRGAERLKAAGVDGIT
LSDNSLATVRIANTTIAAQLKLNYGITPIVHLTTCDHNLIGLQSEIMGLHSLGIEDILAI
TGDPAKLGDFPGATSVSDVRSVELMKLIKQFNSGIGPTGKSLKEASDFRVAGAFNPNAYR
TSISTKSISRKLSYGCDYIITQPVYDLANVDALADALAANHVNVPVFVGVMPLVSRRNAE
FLHHEVHGIRIPEPILTRMAEAEQTGNERAVGIAIAKELIDGICARFNGVHIVTPFNRFK
TVIELVDYIQQKNLIKVQ
>A0A7C7PBZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophaga sp|TrEMBL
MAKNLTLSCEFFPPKTEKGIANLSAVREKLVPLKPEFFSVTFGAGGSTQDNTMDAVIDIQ
KQHAVTNIDAAPHLSCVGSSAERIRALLDTYRNNNIHRIVALRGDLPSGMQAPGDFRYAN
ELVEFIRAETGDFFTIEVAAYPEVHPQAQSAEDDLINFKRKVDAGANSAITQYFYNIDAY
RYFVDNCQKHGIDIPIIPGIMPINNFTQLARFSANCGAEIPRWLRKKLEAFYDDSASMNA
FTVDFLTDFTQQLIELGVPGIHFYTMNKVDPTLTICDRLGLIK
>T0CY30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicyclobacillus acidoterrestris (strain ATCC 49025 / DSM 3922 / CIP 106132 / NCIMB 13137 / GD3B)|TrEMBL
MATKDQVWPAHSLQVGDRRYVIGDGAMATYLHQRGVPIRVSAEALNLSDPALVEEVHRAY
VQAGSTMIQTNTFAANRRSLARHGLADRVQEVNQAAVAIARKAAGQAASVYGTIAPVEGG
NRYGSALLNEERQQLQAFYEEQVEALAAAGIDGWILETFPDLEELLVAVEVVTAHSNLPI
VANLSPEEIGVTRDGVGLAEAFTALRAAGVHVTGINCRLGPYGILRSFEQLLPLADGSGQ
FAAMPNGGMLHKTDDGALSYTGDEENFADIMLRMANLGVTWLGGCCGTTPAHIRTLVSRL
KTSTDESATTTAQLGAVEGRPWRVANRDDKPTVGEILPPTPQSLVERVQTKTTIVVELDP
PKTLNCDKFLEGARALRDAGCDLITMADNSLGSVRVSNMALAGMLQQEGIEPLVHVTCRD
RNLIGQQSHLMGLSVMGVRHILLITGDPSRYGDLPGASSVYDVSSIDLTKMVRRLNDGVG
FSGKALTRPAKFVIGTAFNPHVRNFDKAVERLKRKVAAGADYVMTQPVYDAAMMERIATA
TLHLGVPVFIGIMPLTSLRNAEFLHYQVPGITIPELVLQQMREASPESAQEVGLAIARDL
CDEACQYFNGLYLVTPFLKYDMTVSLTKYIRANTAAAVRSS
>A0A2Z4FQW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradymonas sediminis|TrEMBL
MEVVNARPVVFDGAIGTQLYERGIYINRSFDDANLTRQDMVRSVHRAYLAAGADVLTTNT
FASNRIKLSRHGLEDKVEAINRAGVELAREVAGDTAFVAGSVGPTGLTPTMLTDVELDEI
RAAFSEQIDALARAGADLIVLETFRQLSEMRIAIEAARAVCDLPIVATMAFDSEMKTGDG
AEPDRVAMLLEQWGADVIGANCMEGPKVLFDVVEQMVGHGVPVAAQANAGYPRKVEERLV
YMATPEYFGVYARRFFKLGVRIVGGCCGTGAEHIRQVAAAARMMGSGRVQVEMARVERVD
SPAEPEMEPVAPAERSDLAAKILRAQRERVLAAPGERPPLSRDNFVVSVEVNPPAGLRIQ
DTIESVKMLMAGGVDVINTADGPRASVRMNNGVFAALARKHAGCEVIVHYCARDRNLLGL
QSDLLGLHVLGLHNLCVVTGDPPKVGDYPHATAVFDLDSVGMLRMISNFNRGLDPAGKSV
GETTHFWCACGAEPAAQDYEREIRRLEHKKAAGADFIMTQPVYDHRVLEKFLEDIAHLEL
PVLVGLLPLASHRNAEFLHNEVPGMAVPDGIRQRMKEAGSGPKARAEGVKIAQEILEQVK
DRVVGAYIMPPFGRYESALEILQSIPGYPEVK
>A0A1Q7MVX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteriales bacterium 13_1_40CM_3_55_5|TrEMBL
MAGDLLARLKKSPVLCDGATGTLLYAKGIFINRCYDELNVSQPDLIRGLHHEYLQAGAEI
IETNTFGGNSFRLARHSMENRVREINLAGARLGREAAKSFDVWVAGSVGPLGIRIEPLGK
TSYEEARAAFREQIAALVEGGVDLLILETFGYLEELHQAILAAREVNPKIPLVAQVTIDE
DGNCLDGSTPETFTPRLEEWGVDVIGCNCSVGPVAMLEAIERVRAVTSLPLAAQPNAGIP
RSVEGRNIYLCSPEYMASYARKFVAAGVRMVGGCCGSTPEHIRVMKSALRASEARSKVVA
PSASGGVATPLPSPALPVEKRSQLGAKLAAGEFLTMVEIVPPKGTDIRKELEGARFLKSV
GVDGINIPDSPRASARMSNQALSLLVQQQIGIEAVLHYTCRDRNVLCIQSDLLGAAATGI
RNLICITGDPPKMGNYPDATAVFDVDAIGLVNIVQNLNRGLDIGGNPIGVGTSFVIGVGA
NPGVPNLDEEIRRFEYKVEAGAEYAVTQPVFDLSLLETFLRQIEHCRIPVVAGIWPLVSV
RNAEFMKNELRVSVPNSILDRMAQAKTPEAAREEGIAIAREMLVAVHHMVQGAQISAPMG
RYASAVDVLEALGSSRPATA
>H8WE53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter nauticus (strain ATCC 49840 / DSM 8798 / CIP 103578 / SP17)|TrEMBL
MESQKQFKRRFSFEFFPPKTDQGKEKLQAVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHQQGISTAPHLSCVGGTREEIGELLDVYKENGINRIVALRGDMPSGMGASGELRYAN
ELVEFIRQHSGDHFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEQMGVTIPVVPGIMPIVNFSSLVRFSDMCGAEIPRWIRKQLEAYGDDTDSIRK
FGEEVVTEMCQKLLKAGAPGLHFYTLNQAEPSLSIWKNLGISDREKIAF
>A0A1G1KLM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica bacterium RIFCSPLOWO2_12_FULL_45_13|TrEMBL
MTFCDKIKANKFIVTSEIGPPKGIDIKEALEDADLIKGKVDAINVTDLQSSVMRLGSLAV
CHLLKDRSIEPIFQIACRDRNRLALQSDLLSAAALGIENVLALTGDYTTLGDHPEAKPVF
DLGSIELLDVIKTLQEGKDMKGNALKGAPKFCVGAVVNPGADPLEPEIIKMEKKISSGAL
FFQTQAVYDIELFKRFLDAAKHLKTTILAGIVLLKSAGMAKYMNKNVAGVFVPDSLIKEM
EETKDKSAQSIEIAARLIKDLKPLCQGIHIMPIGWDRKVPLVLSAAEL
>A0A4Y8C194|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter sp. CH185|TrEMBL
LDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEEYQIPSIVHLPCIHSSKEKITQIL
QKCKEKNLNQILALRG
>A0A522QP38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidimonas sp|TrEMBL
MNSEQAVSLEFFPPRDIAAQEKLVRSAKQLLVVRPAYVSVTFGAGGSTRVGTTNAVRILR
NLGYDTAPHISCIGATRAELAEILDGYRAQGIHRIVALRGDLPSGMGPQLGELHYASDLV
RFIRERSGDWFNIRVAAYPETHPQAMTAAGDLDRFVEKIKAGADAAITQYFFNADAYFDF
VDRVRARGVAVPIVPGIMPITNHSQLVRFSNMCGAEVPRWIRLRLADFGDDRASIKAFGV
DVITHLCRSLLERGAPGLHFYTLNGAEAVLG
>A0A4U8SKN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. MIT 05-5294|TrEMBL
MQNSFKASKSYTQDSFSSAQIESFIEKLLGKEKCFTYEFSAPASFNLQPLFDNLKSEHFI
AKLDAFVCTDSPLGKLKHSAILASLKIQNTFKIPSITTISMRDKNTLALQSDLLGMNSLD
LRLILALTGDPLRLGNQPQAKGVFEGNSLLLLRIINALNQQKDINSENIHGDSKPIYPFC
VLNSYANKKENLYRKMQEKIQNGAQAIFTQPIYDPNIAQELLQWCEEINAQCQTKCVLVF
GFFPIFSYKTALFLHHKLPGVFVPQDWLIQMQEASLKGTESQVGLEKNKMLFQTLYKLHQ
KFHFMSANKPDLIEKIIC
>A0A0P6YAJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ardenticatena maritima|TrEMBL
MTHPLLMRLAQGPLLTDGAMGTQLYSRGYSFKQGFDSANIERPQVVRDIHEAYLLAGADV
LETNTFGANRVKLAEHGLQDRVAEINRAAVQIAQAAREALRQPAFILGAVGPLGRMLAPL
GALSPQEARAIFREQIQALIEAGVDGIILETFSSLAEIQEALRAAKEIAPDIPVIAQMTF
GRDGVTKLGHAPVDVAAALLANGADVVGANCGIGPRSVLAAIRTMQAQYPHATYSAIPNA
GWPEQMDGRILYPATPEYFANFAREAAEMGVRLIGGCCGTTPDHIRAMRAALDSWQAGEP
IPARPREPVAVHVRHIAENPAPTALARAFASGHFVTTVELEPPRGVDLTDLLNTAAMLKG
AGATVLNVADSPLARMRMSPWAVASLIQSRVGIETVLHFPTRGRNLLRVQGDLLAAHALG
VRNIFVVMGDPTAIGDYPDATDSYDIVPTGLMKLIKEGFNQGRDFGGNDLGAPTHFLVGC
ALNFGAANLEREVKLLRKKIASGADFCLTMPFYDPDVPRRFIEAYGGPVEIPVLMGVLPL
YNERHAAFLHNEVPGITIPEHVLERMATAENKPQEGVRIALELIDAVRDLVDGIYIMPPF
RKYDIAAQIIRAVYRGNHANAMQEE
>A0A087S3S5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marine Group I thaumarchaeote SCGC AAA799-P11|TrEMBL
MTIRYEANPPKILPDVDTDQSIKKFIERIKNISKKCDAIHLTENVLGFQRVSPLEVGKII
KEEIPDLPITVSLRVRDKSEEEIFEFAEKCIEIGFAGILVLMGDPSQTGKVDSGQIPSLT
VKKLREKNVDSKIDLYLSVSNKPNFSKLAKKKDARPKGFMTQVVQNTEQVQALSDNLKEF
SIIPIILFPSQKNEKSAKFLGLDLESYSKEFEEVLRKSHEITGDVLLTSPNDFTGLNEFL
GKTTF
>A0A5U8T8P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Havana|TrEMBL
MSFFHANQREALNQSLAEAQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPSL
>A0A533J873|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium icense|TrEMBL
MTEFAIPAPDGQRVLPSPKISFEFFPPKTEEMERNLWDTINRLAPLAPNFVSVTYGAGGS
TRERTHSTIARILGETQLTPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPATGI
GTAYVAHPQGYQTSPELVAGIKKRHPDIDVSVSAYPEKHPEARDFDADIDTLKAKVDAGA
ARAITQVFFDNDLYLRYLDRVRARGIDIPIVPGIMPMHNFKQARNFVTRTGTTVPNWLAE
KFEGLDDDAETRKLVAATIAAGQVQKLAKHGVDTFHFYTMNRADLVFAIAHLLGIRPKGA
AKAA
>A0A3A8UKR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium 1XD21-70|TrEMBL
MKIRDILAKGEPTLSFEVFPPKTEDKYEPVEQAALEIAGLKPAFMSVTYGAGGGTSRYTV
EIAAMLQAQGVTPLAHLTCVSSAREKVTSVLGELKARGIENVLALRGDIPADGQVEKDYH
YASELIAEIQKSGDFCIGAACYPEGHVESENKLQDIHYLKEKVEAGCDFVTTQMFFDNNI
LYNYLYRIREAGVTVPVVAGIMPVTNKAQIKRICAMSGTYLPSRFKAIVDRFGDNPAAMK
QAGIAYATEQIIDLIANGVNGIHVYSMNKPDVAARIRESLSEILS
>A0A074X883|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans EXF-150|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEIAAPEAPQ
KVNGATNGEKHEEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>I0IE44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01)|TrEMBL
MHIADLLDRGRPSFSFEFFPPKTAEASDELFATILELRELGPDFVDVTYGAGGSTRDLTA
ELVARIRREAELETIPHLTCVCHSREDLEAILEGWAADGVSNVLALGGDLPRDKPDWDRS
RDACRHAADLVALIKQIGESGHAEARGFGVGVAGFPEGHPGTPNRMEEMDHLKAKVDAGA
DYICTQMFFDNHDFYDFRERCELAGVGVPIVAGIMPITSAKGMRRMAELAAGSRYPASLL
KSVKRAVDAASPAGERAVDDAVSDIGVHWATEQSRDLLDHGVAGLHYYTLNRSDATRKVY
KSLGITPRLAGAEAAREAAPSS
>A0A2A7ABG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MLDVRKLLAQRPLLFDGGMGTYYKAKPGQECEQANLTDPEGILAVHRAYLAAGADAIKTN
TFSLPRLAAAQQPGWEQLADAGWQLAVKAAGETGAAVFADLGPAPDTENLPAEQVYLAVA
KRFALLGARNFLFETLSAEDGVLEAIRALKQTVPEAFVLVSFAVLPDGYTREGRYCAELV
RRVAQSGVVDAVGLNCVSAPGAMRALVQQLGDAGLPLSVMPNAGYPVVARAQVRYQGKPE
YFARELSRLASEGVRILGGCCGTTPQHIAALRTALDALPEVLPAAPAAKPAVAAKPAVET
DDAFLRKLRAGQRVIAVELDSPKDADLTAYLEGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGMNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSPITVFGALNLNARNFEVELRRAAEKLENGMSGFL
TQPVLSAQAVENLKKTRETLGERAKILAGILPVVSQRNAIFMENEVNGIHVDDAIIQRFE
GLDRAAGEELGLEVSVQAAKAAAPYADGFYLMTPFNRVALMERLIARLRTEVTG
>A0A564UE29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MTDIREYLAHKPLLFDGGMGTYYKAAPGADCEMANLTDPEGVKKVHAEYLAAGAQAIKTN
TFGLPRMAAAQMPGWEELAEAGWKLACDAAAEKDAAVFADLGPAPDTEAAPAGSAYGLVA
QQFAALGAKNFLFETLSSDVGIVEAVKALRVAVPDAFVMVSFAVLPDGYTREGLLFRDLL
RRMEQSGVVDAVGLNCVSAPGAMKKLVQGLGETLLPLSVMPNAGYPVVTRARVLYQGKPA
YFAREMGQIAAAGVRILGGCCGTTPAHIAALRAELDALPQRTEAAPAAKLSTGTAPAVEK
DDAFLRKLNAGEKVIAIELDSPRVADLSGYLEGARRLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGMCALPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSAMTVLGALNLNARNFEVELRRAVEKLENGMSGFL
TQPVLSAQAVENLRKARQTLGERAKILAGIMPVVSQRNAIFMENEINGIHVEEDIIQRFA
GLDREQGEALGLEVSMQMAREALPCADGFYLMTPFNRVALMERLIARLKTELLDAEG
>A0A7K2Z2J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID3343|TrEMBL
MSPGAASTQTGRTPVIRDLIANGNRSFSFEFMPPRTEKGVRTLWDAIRRVEALAPTFVSV
TYGAGGSSRTHTVDTTERIATETTLTPVGHLTAVGHSRAELRNIIGQYANAGVRNVLALR
GDPPGDPNGAWVAHPDGFTYAIELVELLRASGDFCVGIAAFPEMHPRSTNWDEDIRHFVA
KCRAGADYAITQMFFDVDDYLRLRDRVAAAGCDIPIIPEVMPVTSAGNLVRMDELSGCAV
PTELAEGVAAVKDDPAAVRAIGVEFATRMSERLLAEGAPGLHFITLNKSTATTEIYQNLG
LGQQS
>A0A1Y6MDG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium andalusiense|TrEMBL
MVNLDQTTQAQSELRVRYNDITRGVYFIGTTPPKTSTPLEEVEGIADRLVNRIKDLAIDG
LIVYDIQDEVSRTQKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSETDAFDEWL
NEAWHEYQVRDIVLVGSPSAKNEVSLPLSAAYQALAENNNNFFTGGIMIAERHAKKGNEH
ARLIEKYQQGCNFFISQAIYDTQATIDILTRYAIECKQDGIKPQRILLTFSPCGSAKTLE
FIEWLGVSVPEATSLRILNASNPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRK
EEIDGSILLYKLLRASMDSHLAKHEFRTLQRNKPTTI
>A0A3E2W6D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium prausnitzii|TrEMBL
MLDVRKLLAQRPLLFDGGMGTYYKAKPGQECEQANLTDPEGILAVHRAYLAAGADAIKTN
TFSLPRLAAAQQPGWEQLADAGWQLAVKAAGETGAAVFADLGPAPDTENLPAEQVYLAVA
KRFALLGARNFLFETLSAEDGVLEAIRALKQTVPEAFVLVSFAVLPDGYTREGRYCAELV
RRVAQSGVVDAVGLNCVSAPGAMRALVQQLGDAGLPLSVMPNAGYPVVARAQVRYQGKPE
YFARELSRLASEGVRILGGCCGTTPQHIAALRTALDALPEVLPAAPAAKPAVAAKPAVET
DDAFLRKLRAGQRVIAVELDSPKDADLTAYLEGARRLQAAGADLLTIADCPIARARMDSS
LVACRVHRELGMNVLPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPAPITVFGALNLNARNFEVELRRAAEKLENGMSGFL
TQPVLSAQAVENLKKARETLGERAKILAGILPVVSQRNAIFMENEVNGIHVDDAIIQRFE
GLDRAAGEELGLEVSVQAAKAAAPYADGFYLMTPFNRVALMERLIARLRTEVTG
>A0A024UTH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aphanomyces invadans|TrEMBL
MGKIIDRLMELEKTGSPSVSFEFFPAKTEDGVFNLLNRVEEMGFQLQPTFVTLTWRSAFK
DEKLWLKIGSHIQNEFKIDVLMHLTCHLPRDQLREILKNVRAAGIRNILALRGDPPIGSE
RWKPVPGGFHNAVELIRFIREEHGDWFCIAAAGYSEVHSEAWNNPNLPPSDQARQLDMIR
LKEKQDAGADFIITQFFFDVDKLLQWIRDCRQLGISIPILPGYLPIQTHNSFLKFTNWCK
TSVPPQVQEALVSIKNDDAAVKKYGIQLAVDTCKKLIANKLSLHFYTMNLARTVRAVLEG
LHLIERERGLPWGAPIMRNKDGSLEKSIEQVRPIFWSNRASSYIARTSEWDDFPNGRWGD
RTSPAYGELSEYYLAYKRPKVARDQLWGRPQTEEDVWNVFVKFIEGSVKQLPWCEQGLSG
ESTIIRENLRWINSMGFLTINSQPRINGAPSEDPSVGWGGKDGFVFQKAYVEFFVPPRLM
QRLVVALADYPNLSYHAFSANGTEYTNSPGPSVTAVTWGVFPGKEIIQPTVVDTASFAAW
KDEAFELWLSQWASAYEPETVSHQLIKRIYDSYVLVNVVDNDYTNGMTHRVGSRVELVVA
QRTATSSRSSPKSSRKA
>A0A848ZLL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenibacter sp|TrEMBL
MKVTEHIAKAKGETLFSFEIIPPVKGRSIQELYDNIDPLMEFNPPFVDVTTSREEYIYID
RAGLLDRKLTRMRPGTVGICASIKHKYEVDTIPHVLCGGFTREETEYLLVDCHYLGIENV
MALRGDAMKEEKYFEPTPGGHLYASDLVTQIHNLNSGQYLHEVIETDNCSDFCIGVAGYP
EKHMEAPSLQTDLKWLKKKVDLGADYIVTQMFFDNKKYFDFVKAARKIGITVPIIPGIKP
IAIKKHLQLLPQVFRIDLPQDLIDAVEKCADNKQIRQVGIEWAINQSKELKAAGVPVLHY
YSMGKSDNIKAIAKAVF
>A0A6I4M663|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura physcomitrii|TrEMBL
MRPVRPDRPPTVRDLLASGERSFSFEFMPPKTDKGARNLWRTIRELEPLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLVGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPDGVEYAAELVRMIRSYGDFSVGVAAFPYKHPRSPDIDSDTRYFVEKCRA
GADYAITQMFFRADDYLRLRDRVAAAACETPIIPGIMPVTRYSTIERSEQLSGAPFPPEV
RARFDAVADDPEAVRRLGIEHAADLCRELLDQGAPGIHFITFNQSTATREVYGLLESGGY
GARGSVPPMTA
>A0A1E2WRM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc sp. KVJ20|TrEMBL
MHHTHSHTAFRRAVQAGEFLVTAEVAPPKGGDPAHMIQMAATLKGRVHAVNVTDGSRAVL
RMSSLMASVILSQNGIEPICQIACRDRNRIGLQADLMGAHALGIHNILALTGDPVKAGDH
PDAKAVFDLEAVRLLQLIRKMNQGVDCNEKPLTDGALDLFVGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFERLEKFMDTIAAGYKKPILAGIFLLKSAKNAQFINRCVPGVN
IPQHIIDRLAKAKDPFEEGIKIAAEQVQIARQLCQGVHMMAVKREDAIAPILDLAGVAPV
NQLVSK
>T2MFS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydra vulgaris|TrEMBL
MVNFIEPSLEETRLLDKSQTLIEKIHKHIGKKKKFFSLEFFPPRTPNGAVNLVARFDRMS
QGGPLFCDITWHPAGDPSGDKETSSCTIASTASNYCGIETMLHMTCANISCDLVLKNLKK
AKNLGIRNILALRGDPPKGEVWMASDENLRFGADMVKFIRKHFQNYFTICVAGYPQGHPD
CTSYEDDLIHLKEKVDAGADFIITQLFFEPNIFFKFLADCRRIGIDVPIIPGVMPIQAYA
SLLQLVKLSKLEVPQYIIDDLEPIKNDDEAIREYGVKLAVSMCRELLSSDDVPGIHVYTL
NREVATTELLQQLGLWRPYQSHRLLPWKPSANLKRLQEDVRPIFWSSRPKSYIHRTSNWD
EFPNGRWGNSSAPSFAELSDHHLFYLKSKESEEERLKMWGEKLDCIEDVYHVFQCYLSGK
KNKWGYKVKSLPLNDDELQPETSLLSDQLYRINGHGFLTTNSQPAVNAALSTDERFGWGG
AGGYIYQKAYLEFFMHKKNVDFLLEVLNDNPRVNYHIIDSHGCYDKTNADRYSPIAVTWG
VFPGKEIIQPTVVDPISFNFWKDEAFSLWIEKWQSLYEPESFSAKIIQSIYNDFYLVNLV
DNDYIKGNCLFDIIDCVIAKSSLE
>A0A1G6NXK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Belnapia rosea|TrEMBL
MDHALPETPPQGTLQRWLTGPRFGGLPNFAELPAPLLSFEFFPPKTDALEAQLWSCIRRL
EPLRPCFVSVTYGAGGTTQARTHATVARIVRETSLTPAAHLTCVGASRGEVDDVARAYWD
AGVRHIVALRGDPPAGAERYEAHPDGYAYAADLVAGLARIAPFEISVAAYPEMHPTALSA
DHDLDNLKRKIDAGATRAITQYFFDTDVYLRFLDRCAAAGITLPIVPGIMPVSNFHQMKK
FSAMCGAGVPPWMGRLFEGLDEDPETRRMVSVVLAAEQVRLLQANGVDEFHFYTLNRPDL
VYAIAHILGARPGAPAAA
>A0A1I4SZC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia ammonioxydans|TrEMBL
MGAPIPGRRAASAHRRGATAHLLTGARYELLPLPGTLDRAAALPPGSTVTVTASPNRGVE
ATVSLTEALSRTGFRAVPHLAARQLTDRAELAGVLDRLDAAGVRDVFVVGGDAREPAGEF
PDGLALLTAMAELRHPMTDVGLPSYPEGHPLIDDDRLWAALRDKQSHATYTVTQLCFDAD
TVCAFAAAARARGIGLPIVVGVPGAVDIGRLLRMSLRVGAGDSVRFLRSHRSIAGKLLRP
NGYRPDGLVRRLGAHVAAGRCRPAGLHLYTFNQVESTLRWVQQARRRAAS
>A0A1Z1W8Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces alboflavus|TrEMBL
MRDMLATGKTTYSFEFSAPKTPKGERILWNSLRRVEAVAPSFVSVTYGAGGSTRAGTVRE
TQQIVADSTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLALRGDPPGDPMGEWVKHP
EGLTYAAELVRLIKESGDFCVGVAAFPAMHPRSDGWETDVEHFVDKCRAGADYAITQMFF
HPEEYLRLRDRVEAAGCETPIIPEIMPVTNVRQLERLPQLSNADFPPELKERILRSKDDP
AAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHQQA
>A0A1V1P847|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Magnetoglobus multicellularis str. Araruama|TrEMBL
MRVSDLYQNNKNVISMEFFPPRNEKAAQNFGNIIDNLSALKPDYMSITFGAGGSTRDGSY
QTVKQVMIDKKQPTVAYIAGYGLGPDDIKDVLNKYKDLGVETIFVIRGDKPKEGTFVPHP
DSFSYASEMIAFIKKHYDFTLGCAGYPEGHIEAESLDKDIEYLKLKVDNGAEYVVCQYFY
DNQLYFDFVEKCRAKGIDVPIIPGVMPVYTVKMTQMLSKVCGSSITDALQKELDAVDADN
KDSVIDMGIQFAFDQCKGLLQSGVPGLHFYTMNRSKTTTEIINRLKQENLL
>A0A4S4MTR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Antrodiella citrinella|TrEMBL
MKFSDKIADYTGSRPFFTLEFFPPKTDQARGFENLQSRIARLSALQPLAVSVTWGAGGNT
MERSLELAGLTQLEHRIDTIMHLTCTNMEKGTVDEALRAAKERGIESILALRGDPPRGEE
HWIPTDPRFRHGVDLVSYIKTTPEFSHFCVGVPAYPDGHAGSEAGENQEIEYLKAKIDAG
ADFIVTQLFYDVEGFLRWQRKVRAKGIQVPIIPGIMPIQTYASFLRLTKLCGTKVPHSLM
SDLVPIRHDDQLVKDYGVTLAIKMIKQLTDQGNVPGVHFCTLNLEKSVHRVTEGLGWAGK
PSRPNRLIAETPAELLQTSERVIDPHRAADSATSGLVVAGLPQQEAGKGELNNASSWDDF
PNGRFGDFKSPAFGDPNPWGASNISRDQALNDWGHPKTVNDLTDMFLRYLHSKLASTPFS
PTPLSPESVMIFPHLERLTRKGWWTVGSQPAVNGAPSTDEVVGWGPKGGYVYQKCFVEFF
VEKEDVEKIEKKVAEDGSGWVDYFAANLNGECRTNVPVDGRNAVTWGVFPGQEVAQSTII
ERESFLAWKEEAFSFWAEWASYYPPDSDVRALLDNVREKRWLVSIIHHDFQKVDALWSFL
FDGEKALVGRA
>Q7M8S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)|TrEMBL
MIKSPKNLKNGTKTMIETLIHKLQKDHFLTLEVAPHASPTLTPLIHSIQSVGLEKRVDGF
VCTDSPLAKLRHSSILATIKLQQSLQKPVICTLSMRDRNSLALQGELMGANEFDVRAILA
LTGDAIRLGDQPQAKGVFEGKSTLLLEIIQSFNRGIDLQGQPLKSPLRPLYPLAVINSYS
QSPESLKKRLRQKIEAGAIGIVTQPIYDLEVAKTLLGWVHEINQELGTFSELVLGYFPVV
SYRTAHFLYSKLPGVYIPNEWLSQLEAASKINPEEERRVGLELSRNIWLGLWDFHPKIHF
MSANNTKLASEILPPPPT
>A0A1H7SJH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia caballeronis|TrEMBL
MKPIELSFEFFPPKTQDGMDKLRATRAQLALLKPKFVSVTFGAGGSTQQGTLDTVLDIAK
EGVEAAPHLSCIGSSKESLRAILARYRSHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IREETGDAFHIEVAAYPEYHPQARSPRHDLEAFARKVKAGADSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNYSQLMRFSEMCGAEVPRWIAKRLESYGDDRESIRAFGVDV
VADLCRRLADADAPGLHFYTLNNAAATAAICERIGG
>F0H1A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerococcus hydrogenalis ACS-025-V-Sch4|TrEMBL
MNIGSKDCVLSFEVFPPRKNLPIESIYNTIDRLIDLKPESISVTYGAAGNDTSKRTFELA
GQIKKHGVESVAHLISIGLSEDELTRKLKILKEKNVNKILALRGDIPKFSYEKGDFDHAS
DLIRSIKEKGDFYVMAAAYPEGHIDSHNLVEDIKNLRKKVDAGCDSLVTQLFFDNEDFYR
FRDMCDLAGIDVPIQAGIMPVINKKQIEKMISLNGIKLPKKFLKIMKRYEDDKIAMRDCG
IAYAVDQIVDLISSGVEGIHLYTMNNPYIAEKIHESIKNLIKL
>A0A117PBL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces griseorubiginosus|TrEMBL
MALGTASTRTDRARTVRDMLATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWLAHPQGLTYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDTDVSHFVD
KCRAGADYAITQMFFQPESYLRLRDRVDAAGCPTPVIPEIMPVTSVRMLERLPQLSNAII
PSALKERILTAQDDPTAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTASLEIYENLG
LHHRPQA
>A0A3D8S6K6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coleophoma cylindrospora|TrEMBL
MYNIPEKETQPVVYSHFNGTTEEILARFCVSELCKGWPVYRDASEWENYRSIFTEKDAYI
WTTWSGGRTIDDFIKVSKEGRANGDFIMHRENGTLVDLNLAKGRAVGKMKATITQRFEID
GISVDIECDGRFIFWCKKEGNEWKAQYKRVFYEKDKMIPVDGKTVPVFEKEELAKYPKGY
QYLAMAQHKIGHPILLDLPTVNNEAFYKILKKMNKSGQELKRKGGRHARSRDHPTIGIRL
NTTLSLNTKVRYTQLQISDMEKITDKIAALPPDANYFSLEFFPPKTTMGSSNLRARLDRM
SRALRPLFVTVTWGAGGSTSAKSLELAELCQRELGLTTCLHLTCTNMSRALIDKALEEAK
VLGIRNILALRGDPPRNGEYGAIEDKAGQSPAQQEEFEWAIDLVKYIRKQYGDYFCIGVA
AYPEGHADELHPLGQSFDHDLPYLVEKVQAGADFIMTQLFFDVESYDHFEKTLREHPSGA
FKDIHIIPGMMPIQSYQMIKRTTKLSHAKIPSDIMSRLDEVRGDDEMVKKVGVDVVSEIV
SHIKSSKIPAPGPRGFHFYTLNLEKAVSFILERTNLIPEPEIADEIAIVDVPLQPLSING
STNLSVPESRSRSMRRQSSVGSDPYNRVIVSAARASNPDYEATAEEASIPAGSINTRANT
LAISEGEGSLGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSVTQAIKLWGHPTSVA
DITDLFIKHIEGKLTAIPWSEEGLNEETNSIKAQLTALNQKGWWTVASQPAVDGVRSTDP
VFGWGPKNGFVFQKAFVELFLPSSDWKALHAKLESLGDDVSYYAANASGDFVSGGCAEEG
STNAVTWGCFTGKEIITPTIIEEVSFRAWAEEAFGIWEEWSRVYPPRSASKALVEQVRDD
VWLVNVIYHGFKETEGLWNLLLN
>C1A5U0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC 100505)|TrEMBL
MTTAAQHPTPRHALLARLLDPEQVVMFDGAMGTMLYARGVFINLCYDELALRSPELVRDI
HAAYVKAGAEVVETNTFGANRPKLSQYGLESQVALINRRAAELAREAAGEHRLVAGAVGP
LGVRLEPYGPTSREEAGRHFAEQMQALLEGGADCFVLETFGDLDELQQAVLAARAVDARV
PVIAQATIGQDLRTAFGATPEDVAVALDRWGVDIIGLNCSIGPQTILEAIERMAAVTDRK
LSAQPNAGMPRDVAGRRMYMASPEYMASYARHLVNAGAKVIGGCCGTTPEHIKAMVEGVR
PLAPRTRVQVGNTREFAVENAAPVGREPVPLGERSRFGAKLAAGQFVTSVEIVPPRGIDT
SKLELDAQALAKAGVDAINVPDGPRAQSRMGAIATSLIIERHGIESVTHYACRDRNLLGM
LSDLLGASALGLRNLLLVTGDPPKMGPYPDATAVFDIDAIGLTNLVSKLNRGLDPGANPI
GEPTRFVVGVGVNPAAIDPEQELRRFHWKVEAGAEYAITQPVFDPAQLERFLESIHDVRI
PVVAGIWPLVSARNAEFLANEVPGVTVPESVLVRMRKANERSKEHALAEGIAIAREALER
VQSSVQGVQISAPFGRVEYALDVLTARTV
>A0A7L5BTL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pikeienuella piscinae|TrEMBL
MTSSTPSISFEFFPPKGPKGAMRLWRSVERLAPLGPRFVSVTYGAGGSTRERTVAAIHTI
RDRARLDVAGHLTCVGATRDETLAVARTYAKLGCRRIVALRGDAAAGDNGFRPHPGGFEG
SEELIRALKAEGRFHVTVGAYPEPHPEAAHDGADVDHLKRKFDAGADDAISQFFFDVETF
LRFRDRCVAAGIEKPIHPGVLPIENFARMQVFAARCGASVPDWMKTAYANAEAADAVDLL
SISVASEMCDTLRREGAGHIHLYTLNNPDLPYQVCQALGVEVKPMRIAAAGGCA
>A0A524NF32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidia bacterium|TrEMBL
VMGVHNVLCISGDNARIGPTPTSNTNILDMDAIQMLWILRRMRDEGIYLDGRKMKSSPRL
FLGAAASPFASEPKFQALREQKKVHAGAQFLQTNLIYDPDRLDLWLEELYKRDILDKVYI
LAGVTPIRSRRMAQYLHHTIPGVTLPEHILERFEEAREDDFEELGVEIALEIIEKIKDKQ
GIHGLHLMSVGWEAIVPRLIEEAGLKQS
>A0A3D8S0G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coleophoma cylindrospora|TrEMBL
MHIKDMLSEAERSGQPTFSFEFFPPKTAQGVQNLYDRMDKMHGLGPSFIDITWGAGGNLA
QLTCEMVSVAQSQYGLETCMHLTCTDMGKEKVDAALQNAYRAGCTNILALRGDPPREREK
WVATEGGFQYARDLVNHIRQTYGNHFDIGVAGYPEGCDDQDDPELLLDHLKEKVDAGATF
IVTQMFYDADNFIEWVGKVRAKGITIPIVPGIMPISTYASFLRRCNHMGCKVPPKWSEAL
EAVKNDDAAVRNIGKGLVAELCRKILGAGIHHLHFYTMNLAQATRMLLEELELLPSQERP
LKQALPWRQSLGLGRREEDVRPIFWRNRNKSYVVRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLRGTNEQNRKLWGEPASIKEVADIFLRYLNNDVESLPWSEAPISSEADVIKEDLID
LNKRGLLTINSQPAVDGVKSSHPVYGWGPKNGYVYQKAYLELLVSPALMEELIERIERNP
DLTYYAVNKSGILKTNAPGDGPNAVTWGVFPGKEIVQPTIVETISFLAWKDEAYRLGLDW
AHCFDADTTSRGLIENMMDSWSLVNIVHNDFHQTHGLFHLFDGLAVPDLETPFQHVNGAK
AHINVVSNTEPVQKVHPLANGVTAAN
>A0A4P7J485|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citrobacter tructae|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGD
LPPGGGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPN
>A0A4Q4V6T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus sp. MG133|TrEMBL
MEKITDKIAALPADSNYFSLEFFPPKTAMGFANLRDRLDRMARALRPLFVNVTWGAGGST
ATKSLELAEICQRELSLTTCLHLTCSNMSRRMIDTALEDAKALGIRNILALRGDPPRAAE
YQDLNGEPEDAIDENFEWAIDLVRYIKKNHGDYFCIGVAAYPEGHADESHPRGQSLEHDL
PYLVEKTLAGADFIMTQLFFDAEAYEKFERTLREHPSGAFKTLPIIPGLMPIQSYQMIKR
TTKLSHAKIPDSISARLDAVKQDDEKVKNVGVDILSEIVERVKEIKSRTPGPKGFHFYTL
NLEKAVSFILERTKLIPPSTPEEDEAVAGVSESTVPKVEINGSTHEPPMPTKHRQRRESI
ARSDVEASIRELPVPAQDRVRRQSTVGSEPRNRVIVSEGSPSHPEYEATQAEASILAEPI
NTRANTLAISEGEGTLGREATWDDFPNGRWGDARSPAYGEIDGYGPSLHVTNAQAIALWG
YPKKPEDINDLFVRHLKGGLSAIPWSEEEFNAETATITSQLLALNSKGWWTVASQPAVNG
LPSSDPTFGWGPQQGFVFQKAFVEFFLPSAEWRVLLEKLQSAEVQDTVCWYAANAAGDFA
SSDLTGGLAGEAMKEPSTNAVTWGVFPGKEIITPTIIEEVSFRAWSDEAFRIFAEWAKVY
GKGSESAALLDAVRADVWLVNIIHHDYVDTDALWNLLLN
>A0A101D365|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp. 54_146|TrEMBL
MSSHEHPLGISFEFFPPNTDAGRDKLIHVRDELAARNPRFFSVTYGAGGSTQARTREVVR
AVSKSGITTAPHLSCIGSEKAQLRDLLTQYREEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRDETGDHFDIAVAAYPESHPQAPNLDKDVENFARKMKAGANMAITQYFFTADAYF
NFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLESYGDDSEAISAF
GTDVISRLCQRLLDGGAPGLHFYTLNQAAPVLKIVDNLTG
>A0A2A6LKB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. M10|TrEMBL
MALKSEAQARDIGISFEFFPPKSEEMEGQLWNTVSELQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRKAGISIPIVPGIMPIQNLTQLKRFAGACGAIIPGFLDARFAGFDD
KPEERAKVAADVAAEQIEDLVRRGIRDFHLYTMNRSPLVSAVLDNLGLSRQAAKNAGAAA
>A0A350UDM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiales bacterium|TrEMBL
MKIIDRIQSGPTLSFEVFPPKSDKPLEPLLGTLKQLYALTPDFISCTYGAMGSNKGRNLE
VVRSIQESGTCEALSHYTCVGNSRADVLSALAEYESAGVENLLALRGDFPAGVEQTNGDF
SHANELISFIRAQTNRFSLAAACYPEKHLLADSLDADIDALLKKQDAGAAFLMTQLCYSV
ENYLRFIDRARKRGVVLPIVAGVLPLLKKDGLVRMTLSNGCSIPAEVATLVGRYGENEES
FRAAGHAFTVSLVQRLIKEGTSGIHLYTLNRYTDVAELVFDAGIREKPRS
>A0A1M4WTD9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium arachidis|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTQGGHASAMDLVHQINDLGRGKYLHNQDEEREEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVKKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEELINEVENAKNNEAVKQIGIEWAITQSKELLDFGVPVL
HFYSMGKSDNIKKVASELF
>N1ZIJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. MD294|TrEMBL
MKIKDIICKQRPTLSFEIFPPKPGADFEPVKKAAEEIAKLKPDFISVTYGAGGGTSSNTI
KIASYIQQLGVTALAHLTCASSTKDEVETVLQQIKQSSIENVLALRGDIPEGSNFPQPNQ
YHYASELVEHIKKSSELCVGGACYPEGHTESATRTEDITHLKIKADMGCDFLTTQMFFDN
NILYNYLYHIREAGITTPVLAGIMPVTNGKQIARICQLSGTILPQRFRSIVDKFGNKPEA
MKQAGIAYATDQIIDLIANGVKGIHVYSMNKPDVAAKIMENLSEIIR
>A0A661EGI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MELKTMISVEFFPPKTTKGIENLSSAIDELQQIKPAYHSVTYGAGGSGQNFTQTTVLSIQ
KKGFTVAPHISCVNSTKSNIKEQLDQYKNNQIDRLVVLRGDLPSGAREYGEFNYASELVE
FINIQYQGFFKIEVAAYPEQHPQTLNPITDIKNFKKKIDAGATGAITQYFYNPDSFYQFI
DECQKQQINIPIVAGIMPITNSQNLKRFSQICGAEIPRYLNNYLNLYEYKPDELIKWTTP
IVAKMCQNLIDNNVAGLHFYTMNKARPTTDIYNLLKL
>A0A6N9FGZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MQFEDEPLVPGERLPIRPGHSSFGRLERVLRAGGFAVTAEIAPPDSANPAEVYERAALYD
GYVDAMNATDGSGANCHMSSVGMCSLLCRRGYAMVMQVSARDRNRIAIQGDVLGASAMGV
ASILCLTGDGVDVGDHPQAKPVFDLDCMSMLSMIRCMRDESRFLSGRKLSVPPPVFLGAA
ANPFAPPLDYRPLRLAKKVAAGAQFVQTQYCFDIEAFKRYMAAVRDAGIHEKVFVLAGVG
PLASARSAEWIRRNVPGVHIPDAIVRRLKGAVNQQREGVNICLEMIHRIREIEGVHGIHI
MAYRQEHWVAEIVERSGVLDGRRPWQPPLDWKNAAWDRGHPALTDAPGRQAVEKVS
>A0A6N9CY21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MRFDDEPIEPGDPLPILPGHHSAGRFERLLRAGVFTITAELSPPDSANAEDVYARARIFD
GYVDGINATDGSGANCHMSSSGVCALLTRAGYAPVMQISCRDRNRIAIQGDVLGAAAMGV
NNLLCLTGDGVAVGDHPGAKPVFDLDAIALLNIVRTMREQACFESGRALTTPPKVFLGSA
ANPFVPPLDFQVARLAKKARAGAEFVQTQYCFDVPLLERFMQQVRDEGLDKRLFILVGIG
PLASARAAEWMRTHVPGVRIPDAVIDRLRRARGKGAAKAEGKRICIDILERVREIPGVCG
VHLMAYRQEEAVAEIIDRSRALDGRIPWYPGRDRHSRPVGEVDSPTELPEEMLA
>A0A6L8CL17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAGRIAASIEISPRQAQESADLSGLFPAGTLVYMTDVGTDSAETIAVGARRLKDLGYCAV
PHFASRRLTTRRVLENRIAMLAAEAGVDNVLVVGGGLEAQAGEFGASIEVLETGLFDRYG
IRRIGVAGHPEGSPDFSDSVAEEALKLKQAFAERTGAEMRIVTQFGFDAKQFIRWADGLS
SAGVDLPVHLGVAGPAKLTTLVKFAAMCGVGNSISFLKKRAGAISTLMAGFDPDEIVDPL
EQHVSGNPDGAIRQIHVFPFGGMKKAAEWLHQRGSWSA
>A0A7C5D3N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratifractor sp|TrEMBL
LGANDFDLRLILALTGDPAKLSDQPGVKGVLERDSTLLLSIIYRLNNGVDYSNKLLRPAP
KPIYPFAVSNAYAKDYKTLQKRMVKKLNYGSRAIITQPVYDVENAKRLLEIFQEAKEISI
RETSKEAQLIFGQFPAVRARTVNFIDDNVPGIKVPKKIIDEMNLAAMDGKEKEEEIGFAL
SKQIFKEISTLHPKLHLMTHNRFQLCMKLIEG
>A0A7C1XNF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MESQKQYPPQFSFEFFPPKTDKGVEKLKLVRDQLGALKPKYFSVTYGAGGSTQQGTFDTI
MSIRQAGFDAAPHLTCVGASRQSLRELLQQYIDHDIHRIVALRGDMPSGMHTSGEFHYAN
ELVAFIRAESGDHFHIEVAAYPEFHPQASNAQHDLDNFKRKIDVGANSAITQYFFNPDAY
FRFIDDCERLGIEVPIVPGIMPITNYSNLARFSDMCGAEIPRWIRKRLEAFAGDTDSIKA
FGEDVVTDLAHQLLEAGAPGLHFYSMNQAEASLAIWKNLGL
>A0A4R1QWP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kineothrix alysoides|TrEMBL
MIIENLFKEKRPVLSFEIFPPKKEAALLSIDETLSTLAKLNPDFISVTFGAGGSGGKNKT
VELAKKIKEEYEIEPLVHLTCINHSEEEIRILLKQLEAAQLKNILALRGDFNPEVPPRHD
FKYAGELVAFIKKNGDFNVSGACYPETHLEAADPVSDIRNLKKKVDAGVGHLVSQLFFDN
QVFYDFVEKVRIAGIDAPVEAGIMPVTNKAQIEKMVTMCGASLPPKLQKILNKYGDNKAA
LFDAGMAYAIDQIVELLSNGVGGIHIFTMNNPVVARRICDGIKNLI
>A0A7C8CXK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MKQNPVVNNSPELQDSIYETKRRLAQRPFPDFISLRQHVSVSFEFFPPTSIELENKLWSC
VAQLAPLRPRFVSVTYGAGGSTRQRTHATVEKILAETLLIPAAHVTCVGAPRDEVDEVVR
RYWDSGVRHLVALRGDSAYPARPFISHPQGYQTAAQLVAGIRKIADFEVTVAAYPEIHPD
AESQEADLDNLKRKLDAGANRAITQYFFNADDFLRFLDRVRAAGISAPIIPGILPVTNFA
RVVKFSEKCGATIPVWMRDLFAGLDDAPDIRQLIAATVAIEQCRLLLEQGINEFHFYTLN
RAELTQAICHALGLREHPEHSLCELNAPGE
>A0A6L9S5W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytoactinopolyspora halotolerans|TrEMBL
MLSEHPADVPAVAPPSVRRQPLADALRTLSYEILPFASTEDAVLANVPRSIPLSITTTQA
KGLERTVDLAVRLSAHGYATAPHLAARQVRDRRHLEDLVARLAAGKVSSVFVIGGDADTP
AGEFADALGLLRALEERGHHFERVGIGGYPEGHAAIDAALIEQAMRDKAAYATHIVTQLC
FDSATTVAWARRLKASGVALPVQVGLPGAVSRQKLIRISAGLGLGQSARFLKKQQNMLWR
FFLPGGYRPDRLVNRLAPRLGERDTALHRFHLFTFNELERTEAWRRAWLDRLSTAHEEGR
>A0A523KHL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
WESGADVVGANCSGGPAQLLRVLQVMRRAVPEGKFSVMPNAGWPEQVGGRIMYAATADYF
AEYARAYTQAGACIIGGCCGTTPEHIAHMRTAIEGVEVSQVRIISIETDEDLEKLSSGQT
GATHLSSKFASGQFVLSVEVNPPRGLSVEKLLAGARLLAAAGADVINVADSPMARMRMSP
WAVCHLVQDEVGLETVLHFPTRGRNLLRVQGDLLAAHATGVRNIFVVMGDPTSIGDYPEA
TDNYDVVPSGLIKLIKHGFNAGVDHHGDEIGEATSFYVGCALNLDTANVEQEIRVLRRKI
EAGADFVLTQPVFEPQRIEQTISAFEERYGPLGIPVLVGILPLYGIKHARFLHNEVPGIS
IPEAIQKRVSAAGDRAPQAGVSMAIEIIDQLKDSVAGAYLLPPFNRYDMAAEIIESVAEK
MPAGGGV
>A0A6L7XRE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MADLSFEFFPPRTAAGAKPLLRAAKALLERRSAWCSVTYGAGGSTRDGTFETVSALREAG
IDVAPHLSWGRDSEDDVVRLLDRYTAMGIHRVVALRGDRPSGVGNAWQGHYAEDLVRLIR
RRVPAPIEISVAGYPEVHPDAPSSGADLEFLKRKLDAGAEVCITQYFYNADAYFDFRDRC
QAAGIFAPIVAGIMPITNYRNLVRFSDKCGAEIPRWLRHRLAELDGDDEALADFGADVVT
GLCQRLLEGDVSGIHFYTLNRAAPTLRVLGNLGL
>A0A2D5TDK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAILSSLRASRPTLSFEFFPPKNDLGSEELLETVNELGKLDPAFVSVTYGAGGTTRERTR
EVVQRIIQDTNVPTIPHLTCVGHTKSEISEILSQYSADQVGTILALRGDPPRDQPNYDRE
GDDFKFAGDLVAFIKENSNEFEVGVAGFPEGHPETQNRLTEMDYFKSKIDQGADYICTQL
FFDNYDFFDYRERCNLVGIDLPIVAGIMPITTISSMKRMADLAAGSRFPAKLLKRLSVAD
GDTAAIRQAGIDHAIEQCQELIEHNVSGLHLYTLNKSSATREIANALTL
>A0A3M1UJP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MESQKRFSPTFSCEFFPPRTPEGRERLATVLGELGALRPAYFSVTFGAGGSTREGTFETV
LAIREAGFEAAPHLSCIGATRESLRAILHRYRESGIRRIVALRGDMPSGMHEPGEFRHAN
ELVAFIREETGDHFHIEVAAYPEFHPQATDALADIRHFMNKVRAGANGAITQYFYNVDAY
VRFIEACEGLGLDVPVVPGIMPITNYHRLARFSEACGAEIPRWLRKRLEAFGDDEASLRA
FGVDVVTALCERLLAEGAPGLHFYTMNRTEPTRTLWRNLGLEGLEVRREA
>A0A5N8YRQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium AD-802-K11_MRT_200m|TrEMBL
MISQLQNRLESGIFTVTAEVTLPDSSIKDELVETALKLSPYCDALNVTDATSAIPHFSSL
AAASILLDNDIEPVMQISARDRNRIAIQGDVLGAHSLGIRNIFCITGDAVIFGDHPDAKP
VFDLDSISMLAAIEKMTKDGCFMSGRKISPKPALFLGAAANPFAPPQSYRPHRTVKKWRA
GASFFQTQFCFDLQIMKSFTEKLIELCNGKPPPILAGLGPLKSSRMARWLRDKIPGVSIP
DHIIERMEKYPQKDQAQVGLEISKETTENLKLIRGISGIHIMAYKWEQAVKDIVEDTGLS
KNKRLP
>A0A523LWW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MASPKAAAGVCSMTLSSKPERAIIHEHVDLVTGLHSCIVFYARMERELRTFRDAVDSNEF
TLTAELNLARRVDAQTLLKQVEMLGPLVDAIQTTDNPYSQVQISSLAAASLILGGGFDAV
AQFTCRDRNRTALASDLLGAKALGVKSVLVLRGDGYKNPKDTKAVFDLDAKELIAKARSL
SGADGFYIGGVATVFKPVAGWQPDELNAKAEAGAQFIQTQLCFDTNVLRRYMEHLVSAKL
TWRTHIVIGVATLPSAEAARWLQRNLRGALMPDTLVERMEQAQDPEAEGVRICAELLEEF
TEIPGVSGANIMTLGSVETIPAAISASGLRAVAK
>F7SYS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter insuavis AXX-A|TrEMBL
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGASRQDLREILQTYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAASVSADMDHFVAKVKAGADAAITQYFFNADAYF
DFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQNLLDNGAPGLHFYTLNHAEAPLAVWKELSV
>A0A520TK27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MAKNSKTFSFEFFPPKTASGQEKVISLGKEFESVPAEYYSVTFGAGGSTQQGTIDTCRSL
FNATKVPIAPHISGIGSDKSSIKSMLQLYKDEGFKKLVVLRGDLPSGFGSAGDFPYAINL
IEFINENFENYFEIEVGAYPETHPEALSPEDDIQHFCQKMSAGVRGAVTQFFFDSDVYFR
FVENCQKHGMDKPITPGMMPIMSKEGLVRMANNCGANIPTSLINKLDSFNNEDDLKKFGA
DYIASLVSALIDKGAPGIHFYTINQLNPTNQIINLID
>A0A3C0L0F1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MQLATHLSQGTISDGSAIDTPKPLYPGAADDLYQHQKNPEAITALMAKIALGARFVQTQY
CFDIDVIRGYSDLLLRHEKPDDLKVLIGLGPLKSAKQADWMRKNLWGVNISDAIVERLEN
SAKPAQTGIEICQELITQIMTLPGIDGVHLMGPECERAAAKIISAFR
>A0A351DR84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSAPRVSFEFFPPKTPEAEASLWKTVERLAPLNPEFVSVTYGADGSTRERTHQVIESILT
KTELKPVPHLTCVGAPRNEIDAIADDYWSMGVRQIVALRGDPEGGAEADYQPHPNGYAYA
SDLVEGLLAKHPFELFVAAYPETHPQAISADTDLDNLKRKVDAGGHRAITQFFFDNAIFL
RFRDRVAAANINVELIPGILPVTNFNTLVRFADACGASIPATLKTLFEGLDEDPSTRQLI
AAHAAVSQAEDLGREGVSDFHFYTLNRADLSFAVCHALGVRGNA
>A0A2E4UU67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MTLPPISIEFFPPKTPAGERKLVKVRKTLGELGPQHYSVTYGAGGSTRAGTRQTVIAINN
AGASVAPHLSFGTDEPEDIATLIEEYKSAGINRVVALRGDAPSGIGAGGQLRFAEELVRF
IRDLTGDHFTIDVAAYPEIHPESKSVAHDIRFFKAKVDAGADGAITQYFYNADAYFRYVD
LCAAEDIKIDIVPGIMPITNYVNLKRFSANCGAEIPRWLDRQLESFGDDAESLMALGTEV
VTKLCERLIAGGAPGLHFYSLNQPEPTREIVRNLS
>A0A358ZDL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSSEELILSQTDHSSSQPSLSFEFFPPRDEDGIAKLLQGAITKLATFNPDYCSVTYGAGG
STRQGTQDLVQAMLATKISAAPHLSIGGSSDAALDQLVEYYQEIGVTKILCLRGDQPSGD
ASKPAYAKDLVERLQQRFPKQFELAVAAYPEVHPDASSAEDDLAHFVAKVNAGASSAITQ
YFYNPEAYGYFLDRCAKAGVSIPI
>A0A353R2Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MGGSQADTALSTLSFEFFPPKTPAGMSKLLDTASRLADLKPAYFSVTFGAGGSTRERTLD
TVLTLMQETGIEVAPHLSCIGATTDGL
>A0A2E1SVU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MSALRVSFEFFPPKTPEAEASLWKTVERLAPLNPEFVSITYGADGSTRERTHQVIESLLT
NTNLQPVPHLTCVGAPQEEIDSIAHEYWNMGVRQIVALRGDPERGAEADYVPHPHGYAYA
SDLVQGLLEKHPFELFIAAYPETHPQAISADADLENLKRKVDAGGHRAITQFFFDNEIFL
RFRDRVAAAQIDVALIPGILPVTNFNTLVRFAGACGASIPQSLSTVFEGLDEDPTTRQLI
AAHAAVSQAEDLGREGVEDFHFYTLNRADLSFAVCHALGVRS
>B6JY06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schizosaccharomyces japonicus (strain yFS275 / FY16936)|TrEMBL
MKISEQLEQLPKDDIHYSFEFFPPKTTIGLDNLTVRMKRMSKTMFPLFSSVTWSSAGSSA
AESLALCASLQSKFGVTSCLHMTCSNVDKESIKKNLDQAKAYGIRNILALRGDPPLKTEH
WNAQKFEMEHAVDLVRFIREEYGDYFCIGVAAYPEGHADTNVPELQQNVDKDIPYLIEKV
RAGADFIITQIFYDSAVYIDFVKKLRTHESGVFKTIPIIPAIMPVQSLTTLRRMARLCNC
VIPHDLMQSLEEVRTDDEKVKAIGVKHVAQMIKDILKNTDTRGFHFCTLNLEKSVARILN
ESGLYERRLTALKAVVNNQKENVADVHNRVVIPKKDHLPSAFEGLYIRADDKQFTRTAEF
FEKQASISVSEGTGALGREATWDDYTNGRFGDPRSPAYGNIDGYGPSLHFAPEESLKLWG
YPVDEDDITNIFKRHVLGETTAIPWIDQPVEAETKTIGDKLAKLIEKKWWTVGSQPAVNA
APSSHAIFGWGPRGGWVFQKAFVEMFMSTMDFEALAQRLHDNPQITYLAGNNKGEFKTNA
SLDSANAVTWGVFPGREIIQSTIIAPVSFQAWRDEAYSIWGEWARLYPAGTPSHKLIQSC
IDNCWLVSVIHHNFLDENALWEVLGC
>A0A5F1SB58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. SEMIA 4088|TrEMBL
MSHIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLTEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEIIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREASRSDALVAERLHQISEGREENQQAMAEIAA
HHTPPQTH
>A0A412MXW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AF19-1LB|TrEMBL
MRVDEVFKQAASQGTAPISFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRSHADIAAKIDEYRTAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELVDAGFCVGAAAYPEGHIACEDLNVSVEHLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A2D9B2F7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MFDDXXLIFTAETTPDLSMDLESSVNKIIPLVGLADAVNXTDSPNXKTKLSSILVAAEXK
XKGLDVILQLTGRDRXRIAIESEIIGAASIDINKILCLTGDQPTENGPKAVNEFNGASLI
ELIDTLNSGKITDGTEIASPKEIFAGAADDLYTHQSKPEAVDSXMSKINSGAKFVQTQYC
FDIEVIKFYSDLLLNNGKDNSWKVLVGMGPLKSAKQADWMRKNLWGIXISDEIINRLDTA
XDPVHEGEKICIELIDQLKELSGIDGVHLMGPNCESQSANIIKSFI
>A0A2D8Y0B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MLFFIKKRLICTQNFVHFYGFLSFFFAVSFERSFCVNKLVDKFDDGDFVVTSELTPPXGT
DVSXLLSKAEVLAPVADAVNVTDSHGSKMSLSPXASAKLLKDAGVEPILQMTTRDRNRIA
LQSDMMGAWVLGIENLIXMGGDPPHLGDHPDAKPVFDIPTEQLIKAAKNLNEGCDLMANS
LKGNTSFNIGAVVNPGADDLAGEVNRLEKKVESGATYFQTQAVFDVXLFAEFMEKVKHLD
IRVLAGIMPIXSAKMALYMNNNIPGIDVPEAIIKXIXQADDILEESLXISSEIIQGLRHT
CAGIHIMAPGWETNIPTLVERSGXAI
>A0A3M1X0R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium|TrEMBL
MNPDFELSFEFFPPKTEQGLANLLATQQALAPLNPRFFSVTFGAGGTTRERTLETILALR
EQDDRIECAPHLSCIGSTRDEIRAILQTYIDHGIRHLVALRGDMPSGMMEPRDFSYASEL
VAFIREQTGDHFHIEVAAYPEFHPQARSAFSDLDWFAHKVRQGANGAITQYFYNADAYFA
FMEDCARRRIDIPVVPGIMPITNHVQLARFSDACGAEIPRWIRKRLEAYGDDMDSLRAFG
TEVVTRMCERLIAGGAPGLHFYTMNRAEPSAGICRALGLGRA
>A0A3D9BUM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium piscium|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICSAIQHKYGVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTLGGHASAMDLVNQINNLGRGKYLHDDEQICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVTKAREIGITVPIIPGI
KPIATKNHLKLLPQVFKIDLPEDLINAVEGAKNNEAVKQIGIEWAIAQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A7T3F547|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis|TrEMBL
MTSNSKILSFEVFPSTTQIGSTNLVKTLDSLRTLSPDFISVTCSNNNYDNIGDTTIKFAD
YVNNTLDIPAVAHLPAAYLDKAQVIEILERLKDKQIKKILALRGDISDEPMKDDFRFASD
LVKFIKDYDDSFEVLGACYPDIHPESVNRVSDFHYLKEKVDAGCDRLITQLFFDNDSFYD
FQERCAIAEINTPIFAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNPIALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNANTAHSIHASISSLFTV
>A0A673IAI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinocyclocheilus rhinocerous|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVLDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGDPIGEDWVEEDGGFNYATDLV
KHIRCEFDDYFDICVAGYPTGHPEAESYDNDLRHLKEKVDAGAHFIVTQLFFRAETFLRF
VKNCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRSYGI
QQAVEMCKVLLASGEVPGLHFYTLNREVATIEVLRQLGLWAEDPRRPLPWAVSAHPKRKV
EDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQ
MWGEELMNEGSVYEVFTNYITGQTNPSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGI
LTINSQPNINGKPSSDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYH
IVNVQGKNITNAHEMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLY
EDESPSRMIIQYIHDNYFLVNLVDNDFPLDSCLWQVIEDMFALLDSPRETQEEGNQLTSG
>A0A4W2CPU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos indicus x Bos taurus|TrEMBL
MVNEPRGNGSPGPRWEGSSSGSESSKDSSRCSTPGLDPERCERLREKMKRRMDSGDKWFS
LEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCG
LETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKH
IRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVK
ACSEIGITCPVLPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
>B8FFJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfatibacillum aliphaticivorans|TrEMBL
MASKFKQALDQGKFVVTSEVAPPKGVNLEKMAHHIELLKDKVDAMNVTDHQSSVMRFPSL
GAALMVKEMGGEPILQMTCRDRNRLALQADLLFAHQRGINNVLCLTGDSVVLGDHKTAKG
VFDLDSSQLVAAVRKLEKGKDMAGNDLDGAVSFCAGAIVTPEANPIQPQLIKFEKKIEAG
AEFIQTQAVYDLENFKNFMEYARQFPVKVLAGIILLTSAPMARFMNKNVAGVTVPQVFID
EMASAPKGGAIKKGIEIAGRQIKQIVEENICDGVHIMAIGKEELVPDIMAAGGLL
>A0A0D2KCH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monoraphidium neglectum|TrEMBL
MKIIDKINEKLAKGERFFSYEFFPPRTEEGVENLLERLDRMAAYGPTFCDITWGAGGTTS
DVTLDIATKMQNSVCVETMMHLTCTNMPVEQLESALKEVRKAGIQNILALRGDPPKGQDH
FETVEGGFSCALDLVRYIRKEHGDFFGIGVAGYPEAHPDSIVDDPEQMKVNYWDNIAYLK
KKIEAGADFVVTQLFYEVERYIQFVKDCRSVGITAPILPGIMPIMAYGGFKRMTGFCKTA
VPKFVSDRMEEIKEDEEAVKAFGIQLGTDMCKQLLDAGAPGVHMYTLNLERSAMAILEGV
GLIDPANVPRPLPWRHIPSSGQRAEERVRPIFWSNRPKSYVTRTAKWQEFPNGRWGNSRS
PAYATLSEHPFMRRHTSNDKRRERARAAWGAALPSLEAVTDVFVRYCQGDAKVLPWAEME
DLHPETGPIKEGLVALNQAGYLTINSQPRVNGAPSNDATFGWGRKGGYVYQKAYVEFFCS
PDKLESLLQRLSGAEGITYLAVNAAGELRTNMAKGTVNAVTWGVFPGSEVEQPTVVDPVS
FEVWKDEAFGLWLSEWGALYEEASPSRQLLQTIHDTWWLVSVVDNDYVTGDLFKALGV
>A0A5J6YWJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus sp. AJ005|TrEMBL
MTRISIELVPRSRSGLRAELATVAEHLPGADTINIPDFPRFSTRSWHGCGFARPRYRAIP
HIRAVDLNPREPLPMAAHLEEHGIDEIIVITGDAPSDMSAKVYNVDAEAAIRRIRRELPH
LKIYAGLDPYRQSLSREQDYLERKLEAGACGFFTQPFFDLRLMDAYADLLPEGAEVWWGA
TSVTSEGSEGYWRTRNHAVFPRQFQPTLEWNRRFAGELLTFARERGQHAYFMPIKADVVE
YLGGIV
>A0A2N9X7K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snodgrassella alvi|TrEMBL
MSFTPLSFEFFPPRTEEGRRKLSITRKQLSQYQPEYFSCTYGAGGTTRAGTLQTITDIMN
DGVAAAPHLACIGASREEMTSLLQTYKDMGIRHIVALRGDVPSGVGFGHQGLRYANELVG
LIRQEFGDWFHIEIAAYPEFHPQSRSAEDDINHFVKKCQAGADSAITQYFFNADSYFWFV
DEVQSRGVNIPIIPGIMPIASFSKLARFSETCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCDHLLQQGAPSLHFYTLNQAGLVSTICQRLGY
>A0A318MW49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Commensalibacter sp. ESL0284|TrEMBL
MTRISVELIPRDRNHIISDMKQVKECFPIADSINIPDLMRFSLRSWNAFQITSSYYTRSI
PHIRAIDINPDLPLPGHDINNLQEILVIQGDPPSDFNKHTYPNSTESILRRYRRELPHLK
LYAAFDPYRRSPKEELEHVLSKKEAGASGFFTQPIFDEKMLELCMDWLHNKTVFWGLSPV
IGPKSKSYWEITNKVVFPHNFETSLQANIDFAKKALQMIKKTNQNAYLMPLRVKLTTYLS
PLQEIFQN
>A0A1C4YQY6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora chaiyaphumensis|TrEMBL
MALGLPSVLPNPQPAIGELIRDARPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVDHSVAELRHVIGRLASVGVRNVLAVR
GDPPGNPGGEWIKHPDGVRYAEELVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQLGTIERSVQLSGAPF
PPALAERFAAVADDPEAVRRLGIEQASEMCAKLLDEGVPGIHFITLNRSTATREVWQRLR
ADARV
>D1BI58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74)|TrEMBL
MTASDVPPTPAGGGPTTAPPGRHAARLRRPTLSFELMPPRNPAAAPKFWSTVDHLVAARP
DFVSVTYGAAGGDRTTAQTVVRRILEHAPVLPIAHLTCVGASRDNVAEVIDEFLAEGVRS
FLALRGDPPRDQPDWQPHPDGVNSSDELVALLREVEAQRCAEDPSSALRSAARPLTIAVA
TFLDGNAAAGTTRSQEVQRLLEKQQAGADFAITQLFYDADSYVGFVDEARRAGVTLPILA
GLLPMTDPARLARVETLTGVPAPKALVRDLESLTDPAARHAHGIRASVELAEAVLAAGAP
GLHIYTFNKHEAALDLLEGVHLGGGPAHPAAADAGPDLASGPWVGASQPTAALI
>A0A1S1LC33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacteroides franklinii|TrEMBL
MTTHPLDRDGPVAELQDPGSIADRLSAVQPGEVPFSVEFMPPRDEAAEARLWRAARVFER
YQPVFVSVTYGAGGSTRDRTVRVTGELAENTTLLPVAHLTAVGHTVDELRAMVGAYVDRG
ITNILALRGDPAGDVNAEWIPHPGGLTYATELVQLVRDLGDFHVGVASFPEGHPQAIDLE
SDTANLVSKLRAGAEYSITQMFFDVDDYLRLRDRVIAADSEQGAKPIIPGLMPITSLRSV
RRQVELSSSTLPASLEERLLRAAGDGPDEDRDEVRKVGVEVTTAMAARLLAEGVPCLHFM
TLNFARATSEVLENLGVRVTPGTGRA
>A0A379A9Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter agglomerans|TrEMBL
MSRPALTWKLCRAFLPVSNFKQLQRFATLTNVRVPGWMSAMFAGLDDDPETRKMVGANIA
MDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAAAA
>A0A7L3GY27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Buphagus erythrorhynchus|TrEMBL
RFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDI
TGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNHAVDLVKHIRNEFDDYFDICVAGYP
KGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLKFMKDCQAIGITCPIIPGIFP
IQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGL
HFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRT
QEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFTCY
ITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGILTINSQPNINGKPSTDPIV
GWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNA
VTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYL
VNLVDNDFPLENCLWQVVEDTFELLN
>A0A8J6UJP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neiella sp. HB171785|TrEMBL
MSYHHAQHLGSLNESLADISGDINVSFEFFPPKTEKMEQTLWSSVKRLAPLKPKFMSVTY
GAGGGERDRTHEIVKRIQNETGVASAPHLTCIDASRDELRGIADEYWNNGIRSIVALRGD
LPEGNPERPDMYAADLVELLKSQHDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANR
AITQFFFNVESYLRFRDRCLTAGIDVEIVPGILPVTNFTQLKRFADMTNVAVPKWMHTMY
DGLDEDQGTRNLLAASIAMDMVKVLRKEGVKDFHFYTLNRADLSYAICHTLGARPA
>A0A1H8B0A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. OV219|TrEMBL
MKPDFREALTKRILTGDGAMGTYLYGMGFPVGVSYEEFNLIRPHVIEDVHRRYYEAGARV
IETNTFSANLASLSNYGLDSEVEAINRAGVRIARAAVGRDAYVVGAVGSIRAGKRKNIAE
AQLEQLFRQQMDALLQEGADGLLLETFYDLEEALLALRIARSLSDVPVITQFAVEKDAVT
QDGVPLAAAFEQLKQAGADVVGFNCRSGPNGILRAIDAIVGDIPLPLSVFPNAGIPDYVD
GKYTFTASPEYFAESARKFADRGARIIGGCCGTTPEHIAAISAALNGYVPQQSSGTRDIE
PVSQAESIQVKEAFVPPAQSEPNIVDMVKERHTVIVELDPPRDLDIQKFMAGAKALNEVK
ADAVTMADNSLAVTRMSNIALAALVQQQAGIRPLVHIACRDRNLIGTQSHMMGLDALGID
HVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNEGIAFSGKPLKQKAKFVTGAAFN
PNVKYLDKAIQRLERKIESGADYIMTQPVYDKELIIRVAEATKHLSVPVFIGIMPLASGR
NAEYLHNEVPGIQLSDEVRKRMAGLEGEAGRAEGVTIAEELLDTALEHFKGIYLITPFMF
YEMTVQLTDYVWRKTSKITR
>Q0I6W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. (strain CC9311)|TrEMBL
MSSALQSSLEAGSVTITAEVMPPRGGDASHALEMARALKGLVHAVNVTDGSRAVMRMSSL
AVARLLLDEGIEPVLQMSCRDRNRIAIQADLLGAHALGIRNLLCLTGDPVRAGDQPKARP
VNELESVRLLQQVTAFNRGDDPVKGELADGPTSIFAGAAADPQCASWSGLTRRMERKKTA
GARFVQTQMVMDAAVLERFCREIAEPMELPVLAGVFLLKSARNAAFINRMVPGACIPDSL
IARLEAAPDPAAEGIQIASEQVQQYLGVAQGVHLMAIKAEERIPAILKRAGVSLPG
>A0A1Q5BV61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora sp. CB01531|TrEMBL
MALGLPSVLPNPQPAIGELIRDGQPTFSFEFFPPKTPQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATDTTLLPMAHLTAVNHSVAELRHVIGRLASVGVRNVLAVR
GDPPGNPGGEWVRHPEGVRYAEELVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTRYFVR
KCQAGAEFAITQMFFDADDYLRLRDRVAAAGCATPILAGVMPVTQLGTIERSVQLSGAPF
PPALAERFARVADDPEAVRRLGIEQASEMCARLLDEGVPGIHFITLNRSTATREVWQHLQ
AAARV
>A0A0A0DD37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Inquilinus limosus MP06|TrEMBL
MVSFEFFPPKSEAAEATLMETVTRLAPLAPDFVSVTYGAGGSTRDRTFGIVTRIQDGSGL
PTASHLTCVGASREEIDGVARALWAAGIRRIVALRGDPPGGAPYQVRPDGYAYAADLVAG
LRRIAPFDISVAAYPEVHPAAPSADFDLDNLKRKADAGADRALTQFFFDTEAFLRFRDRA
AASGIGLPIVPGILPITNFARTKEFATACGAAVPDWLEMLFEGLDETPDTRQLVAASVAV
EQCRLLQTHGVEEFHFYTLNRAELTLAICRFLGIRPRRAEACAA
>A0A2V4C276|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium hydrophilum|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEFIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCHYLGINN
VMALRGDAMKHEQSFVPKDGGNHYAVDLVRQINDLNCGKYLHEVMDIDNRADFCIGVAGY
PEKHLESPSLQSDLRRLKEKVDAGADYVVTQMFFDNAKYFAFVEKAREMGITVPIIPGIK
PIAVQKHMQILPQIFRIDLPEDLIHAVDKCKNNAEIKQVGVEWAIQQSKELKEAGVPFLH
YYSMGKSENIRQIASQVF
>A0A4R0F1D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4178|TrEMBL
MSKHIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFHIEVAAYPEMHPQADSFDLDIQHFCDKANAGANAGLTQFFFNPDAYFYFV
ERIQKEGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A506V4A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mixta tenebrionis|TrEMBL
MSFFHANQREALNQSLAELNGRINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHAIIKGIKDRTGLEAAPHLTCIDASREELRAIAEDYWHNGIRHIVALRGD
LPPGSGRPEMYATDLVALLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFAAMTNVRVPGWMNTMFA
GLDDDAETRKMVGANVAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAAALVA
>A0A284QWA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armillaria ostoyae|TrEMBL
MAVSITWGAGGSTRDRSLDLAGLAQTEYNIDTILHLTCTNMMQGMVDDALAAAKSRKIEN
ILALRGDPPRGKEEWIPIDPRFQRGVDLVSYIRSSPQFSSQFCVGVAAYPDRHPDSLHDE
DTEIEYLKAKVDAGAEFIVTQLFYDVDQFLRWEKKVREKGISVPIIPGIMPIQTYSSFLR
LIKLCGTSVPSFIMSDLDPIKHDDQLVKDYGVKLAVSMIRRLTSEGKVPGVHFSTLNLEK
SVQRVLETLQWAGAAPPTYNKLIEQDTHDDRSVTPSSASRAAKYGLATISTTNGEAGSGE
LNNAATWDDFPNGRFGDFKSPAYGDQDPYGNVGTITLGPWGHPQTINDLTTIFLDHLHSK
IPTTPFSPTPLSPESLMILPHLEKLTKRGWWTVGSQPAVDGAPSSDEVFGWGPRAGFVFQ
KGFVEFFCTEDDLDIIEKEVTDNGKGWVHWFAGNAKGDYRGNIPDDGRNAVTWGVFTGQE
IIQTTIIERESFLSWKVWIFTIELGGALTVAQG
>A0A7X7I039|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp|TrEMBL
MHISEILKKNRISFSFEFFPPKDQHASNLLFTSISELIPLEPAYVSVTYGAGGSTQELTH
DLVMRLQNETKLTVVSHLTCIGASKEKIHAILSDYDKNCISNIMVLRGDPPKGSVSPVHH
PDGFKHAAELVAFIKKHFPHMGIGVAGFPEGHPETPNRLTEIDYLKAKVDEGADYICTQL
FFDNRDFYDFCERCQIAGIKIPILAGIMPIATRKGMTRMADLALGTRYPAPLLRALHRAE
TDEHFEKVGIHWATEQVRDLIDNGVKGIHFYTLNKSKATLQIYDSLGVTNSSGLTR
>A0A7X7AHB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oxalobacter sp|TrEMBL
MSSHHFSIEFFPPKTPEACERLRETRRQLYQLSPEYFSVTRGAGGSTSEGTQDVALEIHN
EGQRAAPHVTCIGTTREMIREKIMDYKSKGIRHLVALRGDLPSAYGVLGEFHYANELVEF
VRAETGDWFYMDVAAYPEMHPQAKSPQDDLDNFVRKINAGADAAITQYFYNPDAYFRFVE
NVQAQGVNVPIIAGIMPITNYASLARFSDTCGAEIPRWIRLKLESYGDDLESIREFGLDV
VTRLCERLLGGGAPGFHFYSLNQAAPVEALCERLRQSGYRT
>A0A7U5DJX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia oklahomensis C6786|TrEMBL
MNPIELSFEFFPPKTVEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVE
DAAKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKIVCERLGL
>A0A1I7H0Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas korlensis|TrEMBL
MSTQEHPLGVSFEFFPPNTDVGREKLKSARDTLAERRPRFFSVTYGAGGSTQNRTLHTVN
AVRESGITTAPHLSCIGSEKAQLRDLLARYREEGIDSLVALRGDLPSGMGGIGEFRYANE
LVEFIREETGDHFEIAVAGYPESHPQAPSLGRDLENFARKVKAGANLAITQYFFNADAYF
HFVDRARALGVEVPIIPGIMPITNYTKLARFSDACGADIPRWIRKQLEAYGDDSESIAAF
GEEVVSRLCQRLLDGGAPGLHFYTLNQAAPSLKVLDNLA
>A0A1Y3TKP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Faecalibacterium sp. An77|TrEMBL
MKNARDILRDRVLVFDGGMGTYYKGRPGMECEQANLADPEGILAVHREYLDAGAEAIKTN
TFGLPRMAAAGLDNWQELAAAGWRLACRAAEGTGAAVFADLGPAPATDAAPAAQTYRAAA
QVFLDLGAENFLFETLSTDEGVAEAAAFIKERRPEAFILVSFAALPDGYTREGRSCRELA
AHMARCGHVDAVGLNCLLAPSAMASVLPAVTGCGLPVSAMPNGGYPLVTRSRVVYQGRPD
YFARELCRIRQRGGVILGGCCGTTPAHIAALRQALESTPMPIAASAPAADVPADTPLLTP
ADPFLQKLARGEKVIAVELDSPKDADLSGYVEGARRLQAAGADAVTVADCPIARARVDSS
LTACKLRRELGMVALPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLARYIHSLAGPGEALPGMTVFGALNLNARNFDVELRRAQEKQASGMAGFLT
QPVLSEAAVDNLKAARAALPDAKILAGILPVVSQRNALYMENEINGIHVDEAIIRRYEGA
DRAQGEALGLEISLEMARAAAPYADGFYLMTPFNRVALMERLIAALKQEAL
>A0A538TQA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Eisenbacteria bacterium|TrEMBL
MKNPFLKRLEAGVVLADGAMGTLLYERGIPFDRSFDLLNLQEPALVQSIHRDYIRAGAEL
IETNTFGASRIRLATHGSGDDARRVNRAGAQLARNAREEIGEVVFVAGAIGPLGKPVAPL
GTIPKEEALAAYIEQVEGLVEGGVDLLIIETQTDLEEMKLAIQAVRRVTDLPLVAEMTFT
EDGRTLYGAYPEDVVRVTQSLGVNVLGANCSVGPQRLLEIVQRLTRRTELPISVMPNAGL
PQFANGRFLYLASPDYFADYAIRLKAAGARLIGGCCGTTPAHIRRMREALARPGTGAAEA
AALDGASAPPPVPPAPQIVVEEPAAGDPASRSLLARKLANHEFVVSVEVDPPRGARPKKM
IEGAQFLKSSGVDVINVADSPMARVRMSSLALASMIYQQVGVETILHFTCRDRNLMGIQS
DLMGAHALGIRNILALTGDPPRAGDYPNATAVFDVDSVGLIRILRQLNAGTDLAGNSIGE
PTRFLIGCAVNPASEDIEAELKRFQQKMDAGAEFTMTQPLYELEPLTRFLEAFGKKRVPV
LLGLLPLQSHRHAEFLHNEVPGINIPEHAREAMRNAGEKGIEVGVEMCRALLLKAKDLVE
GAYLMPSFGRYEVVARVAEVVRTAPKRAPKAASPA
>A0A2U1FKX4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora cinnamomea|TrEMBL
MSESFTEALARRVLLCDGAMGTLARASGGQVEGPGAELCVVAPELVGALHERYLAAGADV
LQTHTFGASRPRLERHGLARRTRELNRAGARLAVEARDRAGRPAWVAGSVSPVTPPGRGS
PVDAAEAAAAIREQVTALVEGGVDLILFETFSRADELLAAVRAVREVTDLPVVAQATFVD
EDGGPLTAAGESPADVVARLADAGAAAVGSNCTLGPQGLLDVLRRMGPNGGGPALTAQPN
AGLPHVVADRSVRFAGDAEHFARYVLRYVTAGARLVGGCCGTTPEHIAAAAAALTAHDAW
APPPDPDPAPAPVVVTSRATVPDELPPEAAAARGRGALDRWLRRRGTREFLVAAEIAGPG
GPDEHLGRARRAVAGGASALWVSRPRARRVTTSTAGLALHLHDGVDVDTVLTVTSWQTSM
LALQADLLGLHALGLRALVCETGNPPVHAEQAVRDGVWEVDGAQLLRMAAGLNRGVDADG
VELGVATAFRLGARVTPGADDLEHEAARAVAKVEAGAEFLVSRPVFEVERLKVVVDALDV
AGCRVPVLVSVGALTGYAQAEYLRHEVPDVVVPDEVLEAMRRAGDGPDAARTGLALASDL
VALAADVVEGAVVRWSGPALPGLDPGTAVARLRAAAGDGTRVRR
>A0A5B9WDI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquisphaera giovannonii|TrEMBL
MHILDIFHAHPTTFSFEFFPPKTDKASDELFETIADLQELKPSFVSVTYGAGGSTRERTH
DLIVRIQRETDLTAVSHLTCVCHSREELGAILDRYAGSGIENILALGGDPPRNLAGYDRA
QDAFRYASELVDFIRGHAIAGDPRGFGIGVAGFPEGHPGTPNRLQEMDNFKRKVDAGADY
ICTQLFFKNEDFYDFRERCELAGIKVPILAGIMPVTSRETLTRIAELALGARIPSGVLRG
VDRCDGDNAGVAKFGIHWATEQCRDLLDNNVRGLHFYTLNRSHATRRIYENLGVKDSESL
VARARA
>A0A1B9S262|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. AC44/96|TrEMBL
MASNTDARRRIGISFEFFPPKSEEMEGQLWNTVNELQDWNPDFVSVTYGAGGTTKAPTLA
TVSRFLSATPLATASHLTCVGATKEETHSVIESFRNVGVKHFVALRGDAPGGVGAPYQPH
PGGYANAAELVAGLRDIGDFEISVSAYPEKHPESRDTAADIEMLKRKADNGADRALTQFF
FDNDNFERYLEKVRAAGIRIPIVPGIMPIQNLTQLKRFAGACGTVVPQFLDERFAGFDDK
PEERAKVAAEVAAEQIEDLARRGIEDFHLYTMNRAPLVSAVLTNLGFKREATKKAGAAA
>A0A329QZ11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytoactinopolyspora halophila|TrEMBL
MMKQLAPGVKRWRQTLLSNPRFEVLPVAGALERVTRLPAGATVTVTASPRRGIEDTIAFT
ETLAARGYAAVPHLAARQFSDETQLTNALRRLHDAGVDDLFVVGGDASASDGAFPDGLAL
LKAIDASGYRFGRIGVPSYPEGHPQIDDDTLWEALRAKRPYATYTVTQLCFDSDAIGRFA
ASTRMHGFDLPIVVGVPGVVAPAKLLRMSLRVGVGDSLRFVRGNRSMARRLLTPRAYRPD
GIVRGLAGQMAEGRVTLAGLHIYTFNETSATVRWLEQRLGHAADEDIPAHVYKDVHEKRP
ADDHAV
>A0A1B3NW39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp. RAC06|TrEMBL
MAHIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSADPEDVYERAKVF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMAKVRDLGFHEKCYILVGV
GPLASAKTAKWIRSNVPGIHIPDHVIARLEGAQDQKKEGKQLCIDIINEVKEIEGVSGVH
VMAYRQEEYVAEIVHESGILKGRRPWKREHGRADDIAAQRMREIGADPVQDQQTLAGLAA
NTQPH
>A0A510IRR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbulbifer sp. GL-2|TrEMBL
MKNPIRISFEFFPPKTPEGRAKLHKTREALQVFNPEFFSVTYGAGGTTRETTSNIVTNMR
RDGISIAPHLSFGGDKEETILNLLNTYKEAGVNRIVALRGDMPSGMGAVAQLVYANELVA
FIRRHTGNLFHLEVAAYPEIHPESNSYDDDIRYLKGKFEAGANSALTQYFYNPDSYFYFI
DQCEKAGIDAPIYPGIMPILNFDNLVRFSRNCGAEIPRWLKKRMESYRNPEDIRKLGLEL
VTDLCETLLEGGAPGLHFYTMNKTDASAYILQSLGLEK
>A0A365P6L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia maris|TrEMBL
MTQLPDSDPTDDGRHPSIVERIATSTTPRVPFSVEFYPPRDEAAEDRLWRAATVFSDLGA
AFVSVTYGAGGSTRDRTVRVVERLVRETDLLPIAHLTAVDHTVAELTDMIRMYGEVGVSN
ILALRGDPPGDPLGEWTAHPEGLHYAEELVRLIHEVGGFHVGVASFPEGHYRARDLEHDS
EILVNKLRAGAEYSITQMFWDVEHYLRLRDRAVAADPEQGAKPIIPGLMPVTSLRQVQRM
VELSGCALPDDLAERLRTAAGDGPEENRAAVREVGIDLTTRMCERLIAEGVPCLHFNTLN
FSKATHEVLTNLSMAPAPGVAAGRI
>A0A4U1KNQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium radiobacter|TrEMBL
MRSETARRDGDIRLSFEFFPPKNAEMESQLWETVDELKKWNPDFVSVTYGAGGSTKAPTL
DAVRRMIADGDLPTAAHLTCVDASRDEVHQVVEEFRNAGVRHFVALRGDPSTGIGTAYQP
HPEGYENAAALVKGLRDIADFEISVSAYPEKHPESASEAIDIDMLKRKADNGATRALTQF
FFDNDVFERYMERVTAAGITIPVVPGIMPIQNLTQLKRFAGRCGTSIPGFLDERFEGYDD
DLEGRARVAAEVAAEQIADLQRRGVNEFHLYTMNRAPLVDAVLENLGLERLRRSAA
>A0A1I5XRN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis arida|TrEMBL
MTGMTTVVERLRGDRPVFSVEFFPPRDAADEAVLWRSIRELEAFDPAYMSITYGAGGSSR
DGTIRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNVLALRGDPPGDPYG
EWVPHPEGLNYAEELVTLVRSLGDFCVGVSAFPYGHPRSPDLDTDTTYLVRKLRAGADFA
IAQLFFEAEDFLRLRDRVAGAGCDALLIPGVMPLTTPRTLHKTIELSGASAPDRLLRRLE
PLAGDPRAFRAEGLDVVTELCERLIAEGVPDLHFYTFNRSKATRELVTRLGLLPARA
>A0A3S3RDV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M4B.F.Ca.ET.089.01.1.1|TrEMBL
MTIRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFLQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A446UTA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Triticum turgidum subsp. durum|TrEMBL
MKVIEKIQEAAANGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPNFCDITWGAGGSTA
DVTLDIANRMQNMVCVETMMHLTCTNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDK
FVQVAGGFSCALDLVEHIKAKYGDYFGITVAGYPEAHPEVILGEEGATEEAYSKDLAYLK
RKVDAGADVIVTQLFYDTDIFLKFVNDCRQVGITCPIVPGIMPINNYKGFVRMTGFCKTK
IPAEITAALDPIKDNEEAVKAYGIHLGTEMCKKILASGIKTLHLYTLNMEKTALAILMNL
GLIEESKLSRTLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTTGWDQYPHGRWGDSRNP
SYGALNDHQFTRPRGRGKKLQEEWAVPLKSVQDINERFVNFCEGKLKSSPWSELDGLQPE
TTIIDDQLVKINSKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYVEFFCAKEKLG
QLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWK
DEAFEIWSRGWACLFPEGDSSRELLEQIQKSYYLVSLVDNDYISGDLFAAFKEI
>A0A3G9ENB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrimonas sp. IBARAKI|TrEMBL
MKISDLIHQTSKPVFSFELLPPLKGNSIKQVFNTIDRLKEFGPKYINITTHHSENTYKED
ENGIIRKVNVRKRPGSVAIAAAIQNKYGIRAVPHIISQGFSKEETEYALIDLSFLGVTDL
LLLRGDTKKLDADQRKMDCHSYATGLQEQVNNFNNGIALDGSTFPAPETPFTYGMACYPE
KHEESPNMESEIYYTKMKAQNGADYLVTQMFFDNQKYFDFVDRCRAEGITIPIVPGIKPI
HLKNQLNVLPKIFRTEIPEDLEHELRKCKTDADAVEVGVEWCLLQSRELVQRGVPGIHFY
ALGATESIYRVAREVY
>A0A6L6G0M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia sp. wls1919|TrEMBL
MSFFHANQREALNQNLAELDGQINVSFEFFPPRSAEMEQTLWKSIDRLKVLKPNFVSVTY
GANSGERDRTHSIIKDIKDKTGLVAAPHLTCIDASPDELKTIARDYWNNGIRHIVALRGD
LPDNSRKPDMYAEHLVELLKTEADFDISVAAYPEVHPEAKSAQADLINLKKKIEAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLERFAKITNVRIPSWMNRMYE
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPK
>A0A6L7LHQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Boseongicola sp. SB0665_bin_10|TrEMBL
MPLSSLSFEFFPPKGIRASLRLWEAVSELAPLGPDFVSVTFGAGGVQHGLTLDTVKAIKK
HFNLVVAAHLTCCNATREETLEVAESYSAAGVREIVALRGDPPTGTGTFRPHPGGFEDSC
ALISALAELKKFSIRASAYPDPHPDATGPGADVEWLKRKVDAGATSAITQFFFEAESYFR
FRDACDAARINVPIIPGILPIEDWTRMKRFARRCDAHVPAWLADAFETAVRDDRHDLLAI
SVCTELCSDLLDGGVENLHFYTLNKPNLTREVIRALRTAPTASLRYVA
>A0A7J9VXY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MSGATGGATGRLSRTIRDGRFAVTAEIGPPRGCDAEAIRRKARLLVGWVDAANVTDNQSA
HVRMSSFAGSMLAMSGGVEPVMQLTCRDRNRIALQSDLISAGAVGIPNVLLLTGDHPRSG
DQPDAKPVFDMDCVQLVWTARWMRDHGRLLSGRDLDPRPNWFIGAVENPFAPPERFRARR
LGKKIAAGAEFAQTQFVFDVERFERWMSEVCDLGLGRRTAILAGVGPVRSLRALAYIRSK
VPGIHVPESVVRRLRGVPPDRVAAEGMQICVETIQRLREVPGVGGVHVMAFGYEKGIPEI
LERSGLAQRRQPAAAGLPDQQEGSDRAR
>A0A7L0NI84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Formicarius rufipectus|TrEMBL
CSTPVLDADRHERLREKMRRRQEAGDRWFSLEFFPPRTANAAVNLISRFDRMGAGGPLFI
DVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDITGHLQKAKRLGLK
NIMALRGDPAGEEWEDEVDGFNHAVDLVKHIRSEFDDYFDVCVAGYPKGHPEAESYESDL
RHLKEKVFAGADFIITQLFFRPETFFKFMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKL
SKLEVPQEIKDVIEPMKDNDAAIRNYGVELAVSMCRELLDSGMVHGLHFYTLNREVATTE
VLKRLGLWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGN
SSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVFTCYITGEPNRNGYRVT
CMPWNDDPLATETNLLKDQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKA
YLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQ
PTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENC
LWQVVDDTFELLN
>A0A510KUW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia wadei|TrEMBL
MRIKDLFEKKEHLISFEIFPPNKNFSEEKLKDVTAELVQYKPDFISVTYGAGGKTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEINDYLQEAKKCNIKNILALRGDVPQGETEDIYN
RGDYKYASELISDLRKNSEFNDLSIGGAFYPETHYENNDLVDLFHLKNKVEAGTDFLASQ
MFFDNDVFIKFKEQAEKLDIKVPLIAGIMPVTNAKQIKRIIELSKCSVPEKLDKLLEKYG
DNPESMKKAGIMYASEQIIELLAYGIRGIHIYTMNKPEIAKEIMKNIEFAR
>A0A5E5PYD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Gammaproteobacteria bacterium|TrEMBL
MKTSFEFFPPRTEKGKQTLHQVRQELSSLNPEYFSVTFGALGTTQEVTLETVLDIQKNDT
VAAAPHLSCIGSKKEIIIELLDQYKAANINRLVALRGDIPSGVRDIGDFHYANELVEFVK
SQYNHHFHIEIAAYPEMHPESKNRLTDLQHFADKVKAGADGAITQYFYDADAYFKFVDAT
EKLGINIPITPGIMPITNYTQLVRFSKMCGAKIPHWILKKLELYQDDFDSLSAFGLEVVT
NLCQTLKAQGVNNFHFYSMNRSQPSLEIAKHL
>A0A431NBC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardiaceae bacterium|TrEMBL
MSLREAFDAGRFAVTAEIGPPRGADPEAVTRKAELLRGWVDAANVTDNQGAHVRMSSLAG
SVLAMQARVEPVMQLTCRDRNRIALQSDLISAGALGIPNVLLLSGDHPRFGDHPDAAPVF
DLDSTQLVHTARTLRDEGVLASGREIGTRPGWLVGAVENPFAPPRSFRARRLAKKVAAGA
EFVQTQYVFDVEVFAAWMARLRDLGVTEGCKVLAGVGPIRSLRVMEFLRSGVPGIHVPDE
VERRLRGVPADRVADEGVTMCVETIQRVAAIPGVAGVHVMAFGYERGVPEILERAGIAPR
PAVSMEGLGHAG
>A0A4Y9JLN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. LYSM12|TrEMBL
MSVTASNHKFDIEETTIRLANYIHNELGIPTIAHLPALYLTKAQVANILTALDQIGVTKI
LALRGDSIPDVAPQNDFQYATDLISFIKDKAPHLDIVGTCYPESHPDSPNQISDIKHLKK
KVTAGCSSLVTQLFFDNDIFYDFQEKCQLADIEVPIFAGIMPIINRNQALRLFHTCDNIR
LPRKFRAILDKYEHDPESLQAAGLAYAIDQIVDLVTQDVAGIHLYTMNNPQVANYIHHAT
YSLFKHSAV
>A0A4Q1ZGP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus australis|TrEMBL
MTKQTPSLSFEVFPPNPEVGNAKLLRALENMQELAPHFISVTASNNKYNIKETTVALANH
IQNELSIPTIAHLPAIYLSKEKVADTLHELDQVGVHRILALRGDIIPGIEPLKDFRYATD
LIEFIKTEAPHFDVIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGVMPILNRNQALRLLKTCENVHIPRKFKAILDKYEHDPKSLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNEDVAYHVHHATKALFEHQPNLEVI
>A0A2A3HW96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. TLI_235|TrEMBL
MALGIPSTRTDRAQTVRDLLAAGDRSFSFEFMPPRNEAAERRLWDAIRRVEALDPNFVCM
TYGAGGSSRGRTVNLVGRIATETTLTPVAHLTAVDHSVAELRNIIGQYADEGVRNVLAVR
GDPPGDPMGEWVRHPEGVTYAYELVELIKGIGDFCVGVAAFPQMHPRSENWDEDIRHFVA
KCRAGADYAITQMFFEVEDYLRLRDRVEAAGCTTPIIPEIMPVTNIRQLERFPQLSGSDF
PDGLKDRFLAVADDPDAVRAVGIDHATAMSERLLAEGAPGLHFITLNHSTSTLEIYQNLG
LHRR
>A0A2S4Y0W8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Ru73|TrEMBL
MTSATARPERTRPARPGLRELLATGRPSYSFEFFPPRTEQGTRTLWQAIRRVETVAPAFV
SVTYGAGGSSRHRTVEMTARIAAATTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLA
LRGDPPGDPQGTWVPHPRGFRYAAQLVELIRSMGDFSIGVAAFPERHPRSPDWESDIQHF
VAKCRAGADYAVTQMFFDVEDYLRLRDRVAAAGCDIPIIPEIMPATDVRQVRRFALLSNA
RFPADLARRLEAAAGDPAAGHRIGVDHATAMARRLLDEGAPGLHYITLNRSTATLEIHRN
LRGTPEYAACGPAGPQGREPSCASPSPVPSPPTT
>A0A0F4GVF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zymoseptoria brevis|TrEMBL
MHITKKLAAAHEKGDATYSFEYFPPKTAQGVQNLYDRMDMMHGFGPAFIDITWGAGGRHS
SLTCEMVKVAQSAYGLETCMHLTCTDMELSKVDDALKEAYNAGCTNILALRGDPPREQEK
WVETQGGFRYARDLIKYIKKKYGDHFDIGIAGYPEGPDETTTADEHIVYLKEKVDAGGTF
VVAQMCYDAELFIEWVQKCRDAGIPESVPIIPGIMPISTHAAFIRRANWTQARIPPAWHE
ALEPIKNDDSAVREVGRDLIVEFCQKLMAAGIMHLHFYTMNLAAAVRMVLEKLDLTPSAE
SPHPDIKPLPWRQSLGLNRRDENVRPIFWRNRNRAYVARTQDWDEFPNGRWGDSRSPAFG
SLDEYGIGLKGTNEHNRKLWGEPQTIDDISKLFVKYMSGKVETLPWSEAPINDEANVLVK
DLIELNNRGLLTINSQPAVDGVKSSHPTYGWGPRNGYVYQKQYLEVLVAPELIDTVIERM
ENNEDITYYAVNHSGELKTNVTADGGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYY
LGLEWSKCYEEGSKSRALITELTKSWYLVNIVHNDFRNQGGIFPIFDGLQVPGVNVEKLA
NGITNGHAENGQTTEEKGKPETNGVPDGNNVVNGANKKA
>A0A2E0GX14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Legionellales bacterium|TrEMBL
MAVPSLSFEFFPPQSDAALTQLGAVAQKLQVASPQFCSVTFGAGGSTQEATPRTVAELQS
QLGMPVVPHISCMAASSDELSVLLDQYQSIGVTQLVVLRGDRPSGVGLWQTEWTYASDLV
AFIQKRYSNTFSIRVAAYPESHPEASSMLADIHALKLKQDAGANSALTQYFFNADSFYHY
QALATQQGVTMPIIPGIMPIMDFEKLQRFSKRCEAEIPRWLVKQMESYSGDTASQYQLGL
DVVTHLCEQLLAMGVQHLHFYTLNQSQTVQAILQRLGVTSHQSAGTVTLSEGG
>A0A2D7S3Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Legionellales bacterium|TrEMBL
MESQKQYKPKFSFECYSPKTPDSIASLQSTQIELAKLNPDFFSVTYGAGGSTRNMTLETV
MDIRDKTGIECVPHISCVGNWDHDINDMLQNYISNNIDRIVVLRGDLPSGTVGYGQFQHA
NELVEFIRKETGDHFHIEVAAYPEFHPQAKSAAVDIQNFKRKIDAGANSAITQYFYNPFS
YYRFVESCEKLNVNVPIVAGIMPITNCTQLVRFSEGCGAEIPRWILKQLYDFGDDRDAIF
KFGVDVVTELCDQLLSSGVPGLHFFTMNRSAASDLIWKNLGLDKRKIN
>A0A2D4YVU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. CPC35|TrEMBL
MTTALQSAIESGQQVFTAEVMPPRGANPSHMLQMASLLKGRVHAVNVTDGSRAVMRMSSL
ASCRLLLDAGIEPVLQQACRDRNRIGLQADLLGAHALGIRNLLCLTGDPVRAGDQTDARP
VHELDSIKLLRQVAGLNLGEDPVNGELVDGATALYPGCAADPQCPSWNGLQRRVQRKRDA
GARFVQTQMVMDPEALDRFQAQLAEPLKLPVLAGVFLLKSARNAQFINRMVPGACIPDRL
IERLDQAADPAMEGISIAAEQVRRYLGIVQGVHLMAIKAEDRVPKILELAGVSPLPV
>A0A4P7TR22|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella flexneri serotype 5a (strain M90T)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A4R0IZN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kribbella sindirgiensis|TrEMBL
MCRVRRVFELICEVEPPTRPDLKKVRHQIGVMSPIADGFLIPDNHIGRATVSSVAVANEV
QLMGARGIACLNSRDRNLLGFRRDLLTAAAYGVERFLFVHGDDPAEGARTSQLTVRRMIE
QTRETTYPGCEPFKVGAATRLTKVPRWKAEADFLYVQVSYDLDELLRWRESVDLDIPVYA
GVMVLASAQMARNLAKLPQLRIPADLIEAVERDRDAGVDHACEQILKIRDSGAFEGVHLI
PVSRYRQVAARLERDLLQRDS
>A0A4R6S5E1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leucobacter luti|TrEMBL
MTSPLLTGSAPTRARFSFEVFPARSGAAALALGHAVQHLSAAGPDFISVTYGANGSNRDA
SVDLLKYLRDHTDALPLAHLTTVGEDRATVRAAIHSIMDAGVHDFLALRGDPPRGLTEAD
PAVAGSLSSLELVELVAEARAERPALTSVGRTAVAAYPNGHPLARSRAEDIDWLIAKQEA
GAQFAITQLFFRAEEYLSFVSDAQRAGLRIPVLPGLMPVSTSAQLRKVAELAGRQAPEEL
TREMEAAGGYAPELGVEHTVELARQLLAGGAPSVHLYTFNRHERVLAVLRELHLLTPDPV
G
>W9YM67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capronia coronata CBS 617.96|TrEMBL
MADDDRLPTLLSSLPPSSHYFSLEFFPPKTSSGFSNLQSRLARMAAALRPLFVTVTWGAG
GSTATKSLELAEVCQRQLGLTTVLHLTCTNMKRSMVDEALESAKEVGIRNILALRGDPPR
EEYRDTNEGGSGGSGTDSNEDFVWAVDLVRYIRRNYGDYFSIGVAGYPEGHADESNPEAG
KQSVEHDLPYLAEKVAAGADFIMTQLTYDINAYQAYEKRLREYVDDDGNKLFANIPIIPG
LMPIQSYQIIKRITKLSHAKIPEDISRRIEAVKADDEAVKRVGVDILSELIDQMKTLPQP
EGMPRGFHFYTLNLEKSVAFILERTGLIPPISEPDTGAAASSDASDSDAIANDDVKTKTP
TPTATSALSNGTTAQNGISPLKAGITKRRTSSVNAQPHNRVILEHARQEHQQQQLQKEAE
KAETTTPVVNQHLAPNRGTGIPASDPTRKHNLMISEGQGSLGREATWDDFPNGRWGPSHS
PAFGEIDGYGPTLKVGPITARRLWNHPKSRDDVTALFRRHVVGELEAVPWSDEIDVDSGG
PAALRAETEVIRQDLLALIENKGYWTLASQPAVDGVRSEDETFGWGPPGEGFVFQKAFVE
FFCPRCEWEEKLRPRLIKYGPQQVGWLKTDAHGEFESSELLEMAEDGRREEEERQEASSP
SKTEDGPTQQQAPTSETTSKGTTTTSTSTIPTSGVNAVTWGVFRGKEIVTPTIIEAESFR
AWGEEAYSIWSEWRRCFPRGSQEEQFLEQMRRESVLVNVVGHTYIGGHAGQGGELWKILL
SDE
>A0A8C0VJK5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyanistes caeruleus|TrEMBL
MQPLPPKRAPKLCNAWTTCCFPVTILSFGRALTMVNETQHTCSASSSSRSDGGSSSGSES
SKDNSRCSTPVLDADRHERLREKMRRRQDAGDKWFSLEFFPPRTANAAVNLISRFDRMGA
GGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKDDITGHLQKA
KRLGLKNIMALRGDPSGEEWEEEVEGFNYAVDLVKHIRNEFDDYFDICVAGYPKGHPEAE
SYEADLRHLKEKVFAGADFIITQLFFRPETFLKFMKDCQAIGITCPIIPGIFPIQGYHSL
RQLVKLSKLEVPQEIKDVIEPIKDNDAAIRSYGVELAVSMCRELLDSGMVHGLHFYTLNR
EVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFP
NGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVFTCYITGEPNR
NGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGG
YVFQKAYLEFFTSSEIVTALLKVLKKYELRVNYHIVNVKGQNITNAPDLQPNAVTWGIFP
GREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDND
FPLENCLWQVVEDTFELLNSPTQQ
>A0A7S9LQY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontivivens ytuae|TrEMBL
MTRPQLSFEFFPPHSPAASMRLWRSVERLAPLGPKFVSVTYGAGGTTRERTRTAIATIRE
RARLDVAGHLTCVGASREETLDVAREFARLGVRRIVALRGDPPKGAEKFEPHPDGYASAA
ELVEGLRSVGDFQIAVAAYPEKHPEAASLATDIDALKAKFDAGATSAITQFCFETETFLR
FRDAAAAAGVPGPIVPGILPVENFTKMKGFAARCAAGVPGWMDTAFGNAQTEEEAHLLAV
SIAAEQASDLMAEGVEHLHFYTLNNPDLTFDICHALGIEASGVNAVAGGA
>A0A8I1WMY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira sp|TrEMBL
MMTVQEIKAVRKNLKVSFEFFPPKTEKMEETMWRSIRRLAPLNPSFVSVTYGAGGTTRGR
THGSVTRIQGETGIPAAAHLTCVGHTKEEIDQIARSYWNEGIRSIVALRGDLPDAGDTYE
PTPGGYAYAVDLVAGLKEIADFDISVSAYPETHPDAPSADFEIEYLKRKIDAGANRAITQ
FFFDNETYLRFRDKCVAAGIDAPIVPGILPVTNFGSLLKFADMCGASVPQRLHWRFEGLD
EDPDTRRMVAFHEAISQVEGLISEGVTDFHFYTLNRAELTYAICHALGIRGPEQAAA
>A0A7X6KXG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas denverensis|TrEMBL
MSVSAEGHTPAVTDGLGAVERPTVSFELFPPRNPDAAPKLWATVQRLAEARPDFVSVTYG
ASGSTRTTTRTLVRRLLRETSLTPIAHLTCVGTSRQELADTVEEFLDEGVRAFLALRGDP
PADGSWQAHPEGLPTASALVGLLREIEARRCASSPAQAVRATVRPLSVAVAAFPRGNAGA
GSTREQDIAALLAKQEAGADFAITQLFYDAPSYLELVQLARDAGVTIPIVPGIIPMTDPA
RLRRVEQLTGVRVPEHVLARLDAFDPETETAERHRAGTRLGIDLVNAVLDGGAPGVHLYT
FNNAGPALDLLDGAGIGGSGAPRARVALAGAAATTPVPVPTT
>A0A7W9L567|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas vesicularis|TrEMBL
MASSASLNLADARALLLSPLGPVARAGSNRDAVRVSFEFFPPKTDEAEANLWKAIRRLEP
LNPAFVSVTYGAGGSTRERTHRTVQRIITETSLRPAAHLTCVEASREEVDEVIEGYKVIG
VDHIVALRGDPPGGAGIGGVYQPRADGYANATELTAAINRISGFDVTVGAYPERHPESPS
IDHDIEVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLT
RMCGACGASIPDWLKAHFDGLDDDPETRKLVAASVAAETCARLQEEGFSDFHFYTLNRAD
LVYAICRVLGVRETAAAQ
>A0A5C4PME7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ICMP22404|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRTLLARYKAVGIQRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVNKANAGANSAITQYFFNADSYFY
FVERVRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A257XEP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methyloversatilis sp. 12-65-5|TrEMBL
MNDSTPRVCSVEFFPPATDEGAEKLRATRRQLRQLNPAFFSVTYGAGGTTRDRTLETVLE
MQAEGLNAAPHLSCIGSTRDNIRQLLQRYQAEGIHHMVALRGDLPSGVVDPGDLRYANEL
VEFVRAETGDWFHIEVAAYPEVHPQARSAEKDLQAFVGKMKAGADSAITQYFYNTDAYFA
FVDDARAMGVDAPIYPGIMPIANFSKISRFSEACGAEIPRWMRRKFEGFGDDAASVRAYG
LDVITTLCERLLAGGAPGLHFYTLNQAGLTSTIWQRLGL
>A0A1H4QVQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis tolypomycina|TrEMBL
MIERLRGDGPKFSIEFFPPRDTADEAVLWKAIRELEPYDPAYMSITYGAGGSSRDGTVRS
IARVATETTLVPMAHLTAVNHSVAELRNVIGWYASVGVRNILALRGDPPGDVYGEWIPHP
EGLTYAEELVQLVRELGDFCVGVSAYTYGHPRSSDLESDTKYLVRKLRAGADFAIAQLFH
DPEDFLRLRDRVAATGCDVPVLPGVMPLTTMRTLQTTIKLSGAPAPRKVLDRLEPLADDP
KAFRAAGIDVTTELCEKLLAEGVPNLHFYTFNRSKATREVIARLGLVPARA
>A0A4Q4TW17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Monosporascus ibericus|TrEMBL
MQIQDMIADAERTGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYFGLETCMHLTCTDMGEEKVNDALAKAYKAGCTNILALRGDPPREKEK
WVATEDKFQYARDLVAHIREKYGNHFGIGVAGYPEGCDDNKDEEQLLDHLKEKVDVGATF
IVTQMFYDADNFIRWMRKVRERGINVPILPGIMPIATYASFLRRANHMNCKIPESWMTAL
EPIKNDDAAVREVGKTLVAELCRKIMAAGIVHLHFYTMNLAQATRMVLEELDWLPTTTRP
RKQALPWKQSLGLGRREEDVRPIFWRNRNKSYVSRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKKWGEPKCIKDIATLFVRYVENDLQTLPWSEAPLTAEADSIREDLIK
LNQRGLLTVNSQPAVNGAKSSHPVHGWGPPNGYVYQKAYLELLVPPELFPEIVSRIHNHP
DLTYYAVTRTGALKTNAPSEGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAYRLGKDW
AHCYDANSPSRVLIDKIMDEWYLVNIVNNDFHQPRTIFEVLEGLYVDNLDVHKTPVSNGV
HNESNGDAGHTNGSGSAAAA
>A0A315QXR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halanaerobium sp|TrEMBL
MKIKNIFDEKEVVFSLEVFPPRPDVPIENIYQTLEELKDIDPDYISVTYGAGGGIRKNRT
CELTSIIKEKYDVEALAHLTCINSDQDTLNKILARLEAKEIDNILALRGDKPVDGEPLGD
YNYAYQLIEHIKKHNDFGVAAACYPEGHLETESLDQDIEYLKQKVDYGVDYLISQMFFDN
SLFYKFRSKAEKKGINVPIEAGIMPVINKKQVGRIIELSDAYFPEKFQKILDKYEDNPEA
LRDAGIAYAVEQIVDLISSEVDGIHLYTMNNPYVARRIKEAVGSLITHINGKKVD
>A0A5C4M1Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis alkalitolerans|TrEMBL
MTNPRREAAGNSRRRAKLAELVRTMSYEVMPFKKTEEDVLAFVPKTVPLTVTVTEAKGIE
TTLSLSERLLGHGYQVSPHLPARQFVDEKHVADVVARLSEGGFTSVFVIGGDAPEPAGKF
TDAYSLLQEMEAAGHPFRQVGVGGYPEGHGKIPQEAIDLALKQKAPLATRVLTQICFDAA
KTASWAAGIASAGVDLPVFVGMPGPVNRQKLMRISAGIGLGQSARFLQKQQSMLWRFLLP
GGYRPSKFARRLAIAAPKTRNNISGLHIFTFNELRGTEQWRQEMLAAVSEKD
>A0A1M4W0R6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldanaerobius fijiensis DSM 17918|TrEMBL
MIKLKDKLQKNEFVITAEVESPKGPDFGDELNRIKKLYGYVDAVNICDNPMANLKMSPIA
LSHIIHEQLGIDTIFHLTCRDRSLLGLQSELLGAWALGITNILTLTGDDPKKGDNPTSTG
VFDCDSVGLARIANSLNNGYDISGNKLNAKTAFLIGGVLNPFDSDAEIEKMKRKIDAGVT
FFQTQPVYDVDAYKRFIDRVGNLNVKIIMGIMPLKSYKMAINFNEKVPGINIPEHIIKRL
AEDPSCGIKIAIEIAKKAKDFADGVHIMPLGRLNAVVQIAEELGRGGKRFEL
>A0A8H7KIU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agaricus bisporus var. burnettii|TrEMBL
MKFSDKIARQSPFFTFEFFPPRTDQGFDNLAARISRLATLHPLGVSITWGAGGSTKERSL
ELATLTQDQCGLDTILHLTCTNAQLGSIDAILKDAKERGIQNILALRGDPPRGQEEWIPS
DPRFTHAIDLVRHIRKSYGDYFCIGVAAYPDGHPDHLIDEGRELDCLKAKVDAGADFIVT
QLFYDVEAFFLWLKKVRQKNINVPIIPGIMPIQTYASFQRLTKLTGAKVPDRIQEELNPI
SHDDRLVKDFGVNLAVDMIQRLVTGGEVSGVHFCTLNLEKSVQRILEDLQWTHAPNRSPN
RLISDAPLPPVSSSAEPDRVVTPITAARDATQTLTSMPTTNNEPGRIDFDNVATWDDFPN
GRFGDFKSPAFGANDLWGNSGSISHEMLREWRNPKTVAELTQLFLDHLDGKISTTPFSPT
PLYPESLIILPELRRLTERGWWTVGSQPAVDGVSSSDEIFGWGPKAGYVFQKGFVEFFCE
EKDVAMLEKRVQDHGNGLVHFFAGNYKGEFSTNVPEDCRNAITWGVFPGQEIIQTTIIEQ
ESFLSWKEDAYSIWSDWASCYHPESEERKLLEEVRDRRWLININHHDYRNPQALWDFIFS
DGDGLVDGPK
>A0A7C6KJ71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistaceae bacterium|TrEMBL
MKIKDLFSEGGPVVSFEIFPPKRDLPIDGIYATIEELKSLQPDFISVTYGAGGSTKERTV
EIASSIRNVYGIRALAHLTCVGTSKEEADSILKELLSCGISDVLALRGDPPAGMDINSVP
RHFRYAADLVAHIRRVYGDAFSIGGAAYPEGHVECDDIELGLLHLKTKVEMGVDFLITQL
FFENEAFYRFLEKARGIGINVPISAGIMPVVNKKQIERIVTLCGASIPPKLARILSKYAD
APEALEDAGVAYAVDQIVDLLSSGADGVHIYTMNRPWVARRIMESIARLLRELRKPKERA
EVS
>A0A1I3HDB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collimonas sp. OK307|TrEMBL
MSKLKQALNERRFVCVLEVVPQQSPVRLVALEQIVQRGHLAGWPLLPAFADRVGLHSDLS
PFEGAGALGDPASSLLHFSGKDRERADLLLQMESMKARGLEQLLLLSGDRLPGHHPDQAP
VRYLESVPALQIAREHCPDWLLGAALNPFKYREEEGGAQYLKGQKKLLAGADFFTLQLDF
DAAKHIEAQTWMRAQVRMKPMLACVMRLSDKRAAVLQAVPGIVITESMRKLLGREQQVSQ
AYASARSLERLALQIVGLQLMGYAGVHVCGVHTLDELLSLEQAIAEQRESMTSLTDWIER
WHASWQMPGAPEVCFVPAIGAWEMGQSNVAATPRERLRYALLSMVHGQFFSRTGWLSRAL
GWGMTRPIWKVGVAADALHAVERTVKRPLVGCDTCGSCRLQETLYVCPETCPKGLANGPC
GGTRLNRCEFADRECVHSVKYRIAKSANQLPVLAQTLIPCIEAGNRHRSSWPEWFEPEDS
TAGR
>T1C065|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
AIGLLEVLSGLNAGVDLGGSAIGAPTAFTAGCAFDPGAEDLPREIARLRRKVEAGARFMM
TQPIYGIETLERALDRLGGAPIPLLLGVMPLYSHRHAVYLDREVPGISVP
>A0P2G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium aggregatum (strain ATCC 25650 / DSM 13394 / JCM 20685 / NBRC 16684 / NCIMB 2208 / IAM 12614 / B1)|TrEMBL
MTAFSNRRSHQAAPSPITASFEFFPPKSDKMAETLWQTVQRLAPLSPSFVSVTYGAGGST
RERTHRTVERILKETELAPAAHLTCVGAARSEIDTIVKDYWDLGVRHLVALRGDPLDGIG
SRYVPHPEGYAYASDLVEGVKKIANFDISVSGYPERHPESGNWQKEIDNLKRKVDAGADR
IITQYFFDNDLFDDYLDRIAAAGINIPVIPGILPIHNFEQTMVFSAKCGTSIPQWLARRF
AGLSNDPETRKLVGVSVACEQVMDLVDRGINDFHFYTMNRADLTFAICHMLGMGKPETKE
TLAA
>A0A2G6HBS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MPQLPRPVHEVRSIVEALAQPQSRPSISFEFFPPKDDAGEVVLWESIRALEKTRPNFVSV
TYGAGGGSRDRTIRVTERIARETTMTPMAHLTCVGHSVTELRSIIGGYAAIGVRNVLALR
GDPQGGLHQGWVPHPDGLNHAEELVALIGELGPFTVGVAAFPDRHPESPSLDHDADVLVR
KADAGAAFAITQFFFTREAYVRLRDRVAARGCTMPIIPGLMPVTSVRQLARMTELSGQPV
PQAVTERLEAVADDPAAVREVGVQITTELARELLADGAPGLHFITMNRSPATLQVWENLQ
GGTAI
>A0A2P6G0T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium|TrEMBL
MGAFNDLVASRERPIVTAEFPSMDGGDLDTVAEAVDRFQPYVDAVNITDNPAAHAHASNV
SMAIAVKQLGLEPIMQVVCRDKNRLAIQADVVGAQMHGVTSFCALTGDDVTAGDEPEARR
VFDIDGPQLVSIMRTLSDGTYLSGRSLKRHRELLIGAVENPFAPPAHVRVRRARMKVDSG
ARFLQLQIGYEPEKLEAFVQGCVDNGVCRDAAVLPTVILTKSAGALRFMESSVPGIHVPG
DVIDRIASAVDPLEESYQLAREQAAQALSLPGIAGIHITDFRHDDSVHRLVHDLRLGPAF
STGATTTHAQTA
>J4IQA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. WH 8016|TrEMBL
MPPRGGDPSHALEMARALKGFVHAVNVTDGSRAVMRMSSLAVARLLLDKGIEPVLQMACR
DRNRIAIQADLLGAHALGIRNLLCLTGDPVRAGDQPKARPVNELESVRLLQQVTAFNRGD
DPVKGELADGPTDIFAGAAADPQCASWSGLVRRMERKKAAGARFVQTQMVMDAAVLERFC
REIAEPMELPVLAGVFLLKSARNAAFINRMVPGACIPDSLIARLEAAADPAAEGIQIAAE
QVQRYLGVAQGVHLMAIKAEERIPAILKQAAVSLPG
>A0A1W1HAX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfamplus magnetovallimortis|TrEMBL
MTKNCCCENDNHGTQKTIPKIDLDNFLTTIEVVPPAGSDPSGILSALDALKDLPVNAFSI
ATNPVAKPRMCALSLSALIQQKTCKPAILHCTTRDHNKLGLQATLWGAKALGIHTVMAAT
GDFVSMNQRKNVSDVKDLNVFELITMANESDMLTGAVLDFRPEANGLEKEVERLEKKAAA
GASFAVTQPIYDRDMARTISITTGHIDIPIIMGILPLRTAKHARFLNEKVAGIAVPEKLL
EKMESASDPIAQGVENAKEMLSIAKEFFRGACIMPPFDHYEIMPDILKSA
>A4FL79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)|TrEMBL
MEMSETTRTLQRHLENARFEVLPLRGVVEQVGNLPEGTTVTVTSSPKKGVEATLDVAARV
RGLGHHVVPHLAARLLTGPAHLAAVLDRIEGLGMTEVFAVAGDSAEPAGPYPDALSLLRA
MEELGRRPSRVGITGYPERHAFIPDATTISAMSEKAAHADYIVSQICYDPHALASWVKDV
RARGVVLPIHIGVPGVVDVHRLLRISLKIGLGESMRFLRKQHGVVTKLLTRYTPEELFDE
LSPHLADPAYGIAGWHFFTFNEVDRTDRWRQDLLARIGEVPA
>A0A1R4GZP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crenothrix polyspora|TrEMBL
MPSQDKQQMFSFEFYPPKTEEGAANLKVVHTTLSKQNPEFFSVTFGAGGSTRDKTFDTVV
SIQAQGLSAAPHLSCVASTKENIRSILKDYQDHNISRIVALRGDVPSGMMSPGEFRYANE
LVEFIRQETSDHFTIHVAAYPEVHPQAHSASEDFKNFKRKVDAGANAVITQYFYNAEAYF
YFVDNCEKHGITVPIVPGIMPITQYTQLFRFSEMCGADIPRWMRKRLESFGDDRIAIQAF
GTELVSKLCQQLLDGGAPGLHFYTMNQSAPTLAIINNLR
>E6QSP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|mine drainage metagenome|TrEMBL
MARPLFSFEFFPPKTPEGANKLCEVRSQLAALHPRFFSVTYGAGGSTRDYSMATVLDIRH
AGLDAAPHLSCIGASRDSLRSVLAEYQQHQIRHIIALRGDLPSGMASGGEFRYASDLVTF
IREETGDWFNIEVAAYPEVHPQAQSAAEDLRHFKAKIDAGANAAITQYFFNADAYFAFVD
ECQGLGITAPIIPGIMPIANYAQLARFSDACGAEIPRWVRKRLEGYHDDLDSIRAFGLDL
ITALSSRMLQQGAPGLHIYTMNQSAVTLELWRRLGLSA
>A0A1R3ENI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. 10N.222.47.A9|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>A0A4R8UHC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Sr47|TrEMBL
MTETTTTRTRGPRIPFSFELYPPKSEAASTALTHTIDRLAAAGPDFISVTYGANGSSRTS
SLDVLRYILDATGVDPMAHLTCVGSSAAEASRLIREFLDAGVRSFLALRGDPPQGIDEGE
TFLGDLGSAAELVQLIHRVQAERVPYRETAIPGLPGARAVKTDREKVRIAVAAFPNGHPR
SRSTSQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRAREAGVEFPILPGIMPVTSPN
RLRRILELSGEDEPADLSIQLQVEPTEQGQREIGITHAVGLARELIAGGAPGLHLYAFNQ
HETVLAVLEGCGAIPASAPHAATQLTAAQRTAHRPTSTGHTHPVKESV
>A0A433HTM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Competibacteraceae bacterium|TrEMBL
MSQSRWLQTLSCEFFPPITTEGVIKLQAVREQLLAMRPAYFSVTYGAGGSTRDRTVEVVL
DTQAHSGVPAAPHLTCIASTQDSVRDLLNHYRIHGIRRIVALRGDMPSGMRDPSEFRYAN
ELVSFIRAEFGDQFHIEVAAYPEYHPQAPSPEQDFANFKRKVEAGADSAITQYFYNPDAY
FRFVDQCAKAGIAIPIVPGIMPITNFVQLARFSDTCGAEIPRWVRKPLESLGEDRAAIRA
FGLDVVSNLCQRLLDGGAPGLHFYTMNLAGPTLAIAERLGLIWTQTS
>A0A387FM06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium jaguaris|TrEMBL
MAHIDENPLGAHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERASIF
DGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFRDYMKKVRDLGLHEKCFILVGV
GPLASARTARWMRSNVPGVHIPDEIIKRIEGAEDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHESGVLKGRQPWKHEANRTDVLVAERLEHIRGGMEENQQQMAEAAA
HHPPHQTH
>A0A736EAT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella typhimurium|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0H4C8J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. PBH53|TrEMBL
MALGTASTRTDRARTVRDILATGKPTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVAHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWETDVAHFVD
KCRAGADYAITQMFFRPESYLRLRDRVAAAGCDTPVIPEVLPVTSVKMLERLPKLSNAHV
PDALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A8F5WY27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKAELRELLNLYKSAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRRLGVQTPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A6P1ZMM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanidesulfovibrio marinus|TrEMBL
MRIADLMTTVEPFVSFEFFPPKEKEKWPDFFHEATRLKEVNPLFVSVTYGAGGTTQGNTL
EIVTKLKQEIGLEPMAHLTCVGADETAIGAFLDQLRANDVENVLALRGDPPKGEKSFIPS
DARFCHANDLVEFIRKSHPDMSVGVAGYPEVHPEAESAMADLDALKTKIQAGGDFIITQL
FFDNALYFDYATKVKAMGLMQPIVPGILPVLSLVSVERIVELCGASVPKAFLEELKDAHE
EDTKAKEKGEPGGRVRAVGIAHAKRQVAGLLEGGAPGVHLYTLNKADACLEIVRSPEVCK
YLRCCPTAA
>A0A1F9LZV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RIFOXYD12_FULL_55_16|TrEMBL
MPNHHCGQNRKTSLIDIPPMLAEKTSPFRQSLFNPAQFTLTLELVPSRGGHSREHDRTLE
LAEKLARDPRIQAVSITENAGGQAALSPEVLGREIQNMGLDVIVHFSSKDKNRNQMESLL
FAWDRLGIRDLLVITGDYPQEGYQGCPKPVFDLGSVHVLDLISRMNQGNYGPDRGRAAIQ
PTVTDPGVNHRRVHNPETSGHRVPQMRERDLCAIHQVCGQVDDKVGAVPCDRLQPTSFLM
GVALSPFKRLEAELLMQYAKLHRKAARGADYIITQVGYDARKFHEVILYLQENGLNLPVL
GNVFIPNLTVASLMHNGKIPGCVITEALYAEIRREAAGPDKGKQARLLRGAKLLAILKGL
GYAGAHLGGPGLTYDNIDFLLSAAEAFAGNWRELIAEMDYWHRDGFYLYKKEPTTGLNTN
ELTPKAGGQSGLQVNYRLARLVHNLAFTQEAPLYPLSKKVCLALEGGRLDSSLTHLEHLS
KFLLFGCQNCGDCTLDDLAFVCPQAGCAKYLLNGPCGGSRDGWCEVYPGKKRCLYVRIYE
RLVACGLPESMREGFVPPRNWALNNTSSWLNFFRGLDHAGARRTSEAGTEQEKKKNRHQI
T
>A0A172WM68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MSQTRSHSFSFEFFPTKTDAGHEKLLATARRLAEYKPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVSTAPHLSCVGDTKAELRELLNIYKDAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARHFEDDLANFVRKAKAGANSAITQYFFNADCY
FYFVERVRKLGVDTPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMESIQA
FGTQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAVWENLKLVR
>A0A0Q7YEI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Root149|TrEMBL
MTHPVRPAHDFRLSYEFFPPKSPEMEEQLWQTVDQLALFEPEFVSVTYGAGGTTKRPTFA
TVERLISKTNLPTASHLTCVDADRDETHDVINELRAMGVKHIVALRGDPSSGVGTAYVPH
PHGYENAAALVAALKAEGGFEISVSAYPEKHPESRDVNADIEMLKRKADAGADRALTQFF
FDNDVFERYMEQVRKAGILIPVVPGIMPIQNLTQLKRFASRCGAGIPAFLDARFEGLDDK
PEERAKVAAEVAAEQIQDLMRRGLDEFHLYTMNRAPLVSAVLTNLGRLPKEKAQTGAAA
>A0A1Q7R8E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium 13_1_40CM_2_61_4|TrEMBL
MGANPGTINTDAEELKRFVYKVEAGGEFALTQPVFDGAVLERFLRRIEPCKIPVIVGIVP
LANYKMAEFLNYEVPGCSVPEPILERMRQAEADGPVRARAEGVRIAQEILERVQGMIQGV
QIRGPFERYETPVEVLSVLNLKGASR
>I4LS59|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gardnerella vaginalis 55152|TrEMBL
MTYKPKFSLEVFPPKRTSPIGTIYDTLDGLRGLDPDFISVTYGTGKSSDRTATARIANTI
RSEYGIKTVAHLTARYLDYDDVDEALDMFDKAGVSGVLALRGDVIENQNAAGVFNHASDL
VSYIHSKRPDLPILGACYPEKHPEAATLQEDIDNLKRKVDAGVTHLISQLFYNNDDFLHF
RDLARKSGINVPIEAGVIPVVNANQVKRMTKMCSSKISEPVLAMIERWGSNPEVLQDAGS
IFASQQINDLVAEGVDGIHLYTMNRPGVTRSIWSNVKPLFTKIV
>A0A2N8RHM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri|TrEMBL
MTTSRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDTKADLRELLNLYKEAGIQRIVALRGDLPSGMGMASGELRYANE
LVDFIRAETGDHFHIEIAAYPEMHPQARNFEDDLTNFVRKAKAGADSAITQYFFNADCYF
YFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIQSIQAF
GEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A0P0CVL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rufibacter tibetensis|TrEMBL
MKVTEHLQNATNTLFSFEILPPVKGTSIQSIYQGIDPLMEFKPPFINVTYHREEYVFKER
ENGLLEKITIRKRPGTVGICSAIMNKYHVDAVPHIICGGFSREETENALMDLNFLGIDNV
LLLRGDAVKTEPGFRPHKDGHSYATDLIKQVVDLNHGHYLDEEMENPVPTDFCIGVAGYP
EKHMEAPNLTADLKYLKQKVDLGANYIITQMFFDNQKFFEFVNACRAAGITVPIIPGLKT
LTTKNQLNVLPRYFNIDLPEDLVNAVEACQTSKDVKQVGVEWTIQQCKELMAFGVPCLHF
YTMSKSDATVAVAREIF
>A0A0N7JNT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia marcescens|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWQSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLRDIATDYWNSGIRHIVALRGD
LPPGGGKPDMFATDLVALLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVAAA
>A0A6L6GHQ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. YIM 103518|TrEMBL
MTKRVPISFEFFPSKTDAGAEKLRTVHKELQLLNPEFFSVTYGAGGSTRERTLSTLNDFN
GKGTPVAPHLSCIGDDKARITELLDIYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDYFNIEVAAYPEMHPQAESFDADIKRFCEKANAGANAAITQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDAESIKAFGHE
VNLKLCERLIEGGAPSLHFYTMNQTEPNRQLVLDLGLA
>A0A7V6BYR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKPDFLQYLRNHVVLADGALGTYLYEKGVELGRNLDLLNLQADELVYSAHEEYIRAGSQL
IETNTFGANYFKLRESGAEDQVREINRAGARIACKAAGHQVCVAGSVGPTGVAFPLEEDG
VSAADISAAFREQITGLVEGGVDLIMVETFSILDEVLLAIQAAREAAPDLPLVAQMVFPA
RGMTVEGLDALSCGGIMAEAGADVVGTNCGRGIDAIVTAVKLMMPLAGEGILLSAFPNAG
LPEMVGHRMIYPAQPSYMAIRAAEMIKCGVHLIGGCCGTSPAHIQEFRSRLKIRPVRIRD
ERIAERPEEEARQEVRDLPGGFLTGLKPGRLPVIVELDPPTHLDVEQVLTGAGELTGAGV
DAISLGDNPLAILRVGNLGMANLIRRRTGVQTILHQTGRDLNALGLQSRMMEAHLLGIEA
VLAVSGDSAGATDQPGVSGVFDLRSYGLLRMLRNLNNGLNMAGRSIKQRTNFSIGAAFSY
RPENPRVQIQRLEKKADLGARFAMTQPLFSREAVEKMIEQTQHLDILIFPGIFPLISSRN
AEFLHNEVPGISVPEELRRRLASYEQAADQCRAALDYIRQLVESIGPMVDGLYFISPLNK
WEIALEFVRLVREHGWRGSGRADRYCSHHTIHSTLS
>A0A831NYM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSEYKSGSNLEKVLKAGHFAFTGECGPPQGANVEKLKEKAQHLKGMVDAVNVTDNQTAVV
RMSSWAASLILLQEGLEPNFQMVCRDRNRLAIQSDILGVYSHGIRNMLCLSGDHQKFGNH
PQAKNVYDIDSMQLIHAVKTMRDEGVFLNGEKIDVPPRLFIGAACNPFADPFEFRVYRLA
KKIDAGADFIQTQCIYNMDKFREFMKRVVDMGLHEKCYILAGVTPMKSIGMARYMAKQVP
GMDVPDSLIKRLQGAGKGKVAEEGIKFALEQIEEFKEMEGVAGVHLMAIEWEHRVPEIAE
RAGMLPRPKL
>A0A1J1IJ50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clunio marinus|TrEMBL
MKFHIINKQKILSKTPLKIIILENFCRENGKFFYSIEVTPKEETKIYFTKLKIQPLFVDI
TWIKNFNLITPIEDAPALKLANEIKSTHVVNSVTCYGLEDHHIEKVLRSELKLKNFTVLR
GDYVDSEQKYKFANELIKEIRRRTSSEEVTIFCAGYSNTHNEAVNADEDLQNLKRKVESG
VDAILTLNKREERERLEAKNSFAY
>A0A6L6HQN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus lichenicola|TrEMBL
MSRPTISFEFFPPKTLDASFRLWETARALAPLAPDFVSVTYGAGGTTRKLTHEAVTTIHR
HYGIPVAAHLTCVEATRAETMEIVQAYADAGIREIVALRGDAPKGQDRFTPHPEGFADTV
ELIEAIAARGDMTIRVGAYPEPHPDSSGTDADVAWLKRKIDAGATSAITQFFFEADTFFR
FRDKCAATGIDAPIIPGILPIQGWAGAKRFAATCGTSVPGWAEEAFSKAAAEGPAAERAL
SERTCVKLCRDLLDGGVDRLHFYTLNKPDLTLAVCAALGVEPVRDLGAVA
>A0A7C4MG89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synergistetes bacterium|TrEMBL
MSQLKDLLERGKFVITAEVGPPKGADLREFKDIVRLLKGGVDALNVTDGQGASMKLSSLA
GCVAILQEGAEPVMQMTGRDRNRIAIQSELLGAYALGVRNLLAITGDYPTLGDNPSAKPV
YDLDSVGILLAASSLMEGRDLAGNPLKGEPPSFYLGATVNPNFEPLEIELIKMEKKIHAG
ARFFQTQAVYQIDIADRFMKEASRLNVKILIGIIPLRSVRSAHFVSKMIPGVKVPQGLIH
RLESAPDPKLEGLRIAAELIRKVREHGLAHGIHIMAIGAERSIPLLLDML
>A0A7C5HPD8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MSFQKRLSAGKFVVLAEMHTPKGVNISKMVLDSRRIKGRVDAVIVPDMDNGVMKMSALAG
GVLMQQQGLETIIHVYTRDRNSMALQGDILAAHVLGIQN
>A0A7X1L428|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MHLKCKFDNGEFALLAELQPPKGTDISRMVANIQPVRDKVDAFVVTDMCNAMLHMSALSS
AMLLQSRGVETVMQVCVRDRNRLALQADLLGANACGIINLLAVTGEDPIFGDHQQALAVH
DLDHLDLLYAISSLQNGKDLAGKDLDGTPQFLIGSTVNSSLKGQALELEIEKMNRRHEAG
ARFFITPPVFDLSCMDAFIERVDPKKYKIIPSVLLLKSLGMVRYIERNLKHVSIPRTLVQ
RIQAAADKGRECLRVTQELVAAMKSEGFSGVQITTLGREDRLSALLGVPAKVDA
>A0A3A4RLR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSDSKLEKILKAGHFAFTGELGPPRGANVEHVREKAKPLVGNVDLVNITDNQTAMVRMA
SWAAALIAIQEGLEPNYQMVCRDRNRLAMQADILGAYALGIKNILCLSGDHQKFGDHPTA
KGVFDIDSMQLVNMVKTMRDEGKFLGGADIEVPPKLFIGAAANPFAEPFEWRVHRLAKKV
SAGADFIQTQCVFNMKKMREWIKRAVDMGLTEKTYILAGVTPMKSIGMAKYMASKVPGMD
VPEEIIKRLQGAEKGKVADVGIEIACEQIEEFKEMKGVAGVHLMAIEWEHKVPEIAERAK
VLPRPQV
>A0A3N5FRI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKPELLSNLQSVLSDGKFAVTAECGPPRGADPVIIRKKGELLRGHVDAVNVTDNQTAIVR
MSSIAACAHLSAMGLEPVMQMVTRDRNRIALQSDILGASSLGIRNILCLSGDHQTFGSQP
DAMNVFDIDSVNLVHMVKIMKTEGKDMSGYDLISPPKMFIGAAANPFADPFEYRVIRLAK
KIDAGADFIQTQCVYNLERFREWMRLAREEGLTEKTHILAGITPLKSEGMAKYMAKKVAG
MDVPELVIKRMGGVPKGKAAGEGIDICLETIAALREIKGVHGIHIMAIEWEETVGRIVEA
AGLSPRPQTA
>A0A525CWT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MRILDLYTEKSPVISMEFFPYRDEKTETSFNKVADDLLNVNPDYLTVTFGAGGSTRDGSY
QTVKTILEKKNKPCVAYIAGYGLGPDEITEVLDRFKSLGVQTVFVIRGDKPRQDDFTPHP
DSFSYASELIRFIKERYDFTLGCAGYPEGHVDAPDFKTDLGHTRTKVENGADYIVAQYFY
DNDYFFNYVSACRDAGIDVPIIPGIMPVYTVKMTHALARICGATLTPALVQKLDAVDPED
KEAVLNLGIDFAVEQCKDLLSRGVPGLHFYTMNRSRSIKEIISRLEW
>A0A1M5Y3D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporobacter termitidis DSM 10068|TrEMBL
MKLTELFQRGEFVVTAEVGPPKGFHIDHLLHEADEYLKGRVHAVNVTDNQSSVMRLGSLA
TCKALKDRGLNPIFQMTCRDRNRIALQSDILSAALFGIENLLCLTGDHTTLGDNPQAKPV
FDLDSVSLLHMVKKLESGEDLAGNPLEGDAPKFSKGAVVSPCSDSVDVQLAKMEAKVKAG
AEYFQTQAVYEPEKFIKFMEKAKQFGVPVQLGIVIPKNAGMAKYMNANVAGISVPDSMIE
ELQKDKEKTKAGITGIEISARIIKECRPYCQGVHIMAMGWESKVPDILAQAGI
>A0A1Y3SJ99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoflavonifractor sp. An85|TrEMBL
MKIAELFGRGRPVFSCEIFPPKKDSPIDSIYQTLDGLKDIRPDFISVTYGAGGSGAVNQS
TQEIACMIEQKYHIPAMAHLTCVGCTKESSLEILETLKAGGVENILALRGDHNPNVGSHT
DFLHANDLVSWIREHGDFGISGACYPEGHPESPDIVSDIRYLKQKVDAGATHLVSQLFFD
NDDFLRFLERCRLAGIDVPIEAGIMPVLSKASIQRMVSMCGASMPRKLTRILARYGDHPQ
AMREAGIAYAIDQISDLIAAGVDGIHLYTMNNPQVARQISDSISAIRSV
>A0A2K2VLA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MIKKIADIYAEKMKMGDPVFSFEVFPPKTSEGIENLFGTIEELAELEPDYISVTYGAGGS
TTRSTLDIARKIQDRFGITCMHHFTLVNQTVEELSRHIELMKDAGLRNVLALRGDPPQEM
GEKFEKIEGGLEYCYELIDLLKEVGDDSFSIGVAGFPECHIDCPLEDLDSAYLKIKADHG
AEFVLTQLFFDNPSYAHYLERVSAVGVKIPIIPGVLPIMDYQKLLRFCDTCGAYICQEVH
KIFAPVAHDLEETVKRGTAYAIEQCGDLLRRGAPGIHFYCLNKTEPVRTIWQQLKDRASE
>A0A1G0B448|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallionellales bacterium GWA2_60_142|TrEMBL
MNKPLFSFEFFPPQTPEGMEKLAATRKQLAALNPEFFSVTFGAGGSTQERTLETVRQIKA
EALQVAPHLSCVGSTRDNVRSLLQTYQQLGVKRIVALRGDMPSGMGSIGEFQYANELVSF
IRAQTGEHFHIEVAAYPEFHPQAKSARDDLANFKRKVAAGANSAITQYFYNADSYFYFVD
ECRKLGVTAPIVPGIMPIVKYSQLARFSDMCGAEIPRWMRKTLEGYGDDNESVQAFGLDV
VTQLCEKLLAGGAPGLHFYTLNQAGPSRELCKRLGL
>A0A3D6BXW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MTFITSDPDRFKITLEVVPPEGADTARLMDKILPIANLSFDAFSVASNPVAKPRMSAMAF
AALLQQKTGNPAILHLTVRDHNRLGLTAELWGAKAMGIDTVIAVTGDPSAKNTDHPATTV
NDLNVFEMITLAKDSGMTTGAVLDFRPEVDGLAHEIKRIEKKAAAGASFIVTQPVYDSDT
ANRIKQGIAHVRVPVLMGILPLLTARHARFLHEKVAGIAVPQSLREAMDTAANPLDAGIE
NACDMLALARHTFAGACVMPPFERFDILDQIL
>A0A3S1WW00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.003.02.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0Y9Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine gamma proteobacterium HTCC2143|TrEMBL
MNRDQRFSFEFFPPKTDAGKEKLKLVSAELNALGPDFFSVTYGAGGSTRANTKDTVISMN
AAGISTVPHLSFGNDDEQVILDLLREYKAAGISRIVALRGDVPSGMGAQRLIYAEELVQF
IRDHTGDHFQLEVAAYPEVHPDAKGPENDIEFLKRKFDAGANSAITQYFYNVEAYFYFVE
QCQKNGIDRPIYPGIMPITNYHNLARFSKSCGAEIPRWICQRLESFGNDSESVQEFGIEV
VTQLCQRLLAEGAPGIHFYTMNQVEPNRQIWKNLGI
>A0A2K8VEP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum sp. SZ-18|TrEMBL
MKVTEHIEKSNGKTRFSFEILPPLKGQNIDSIFNNIDSLMEFNPPFIDVTYHREEYVYKE
LENGLLQKQVVKKRPGTVGICAAIQNKYNVDAIPHVLCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKSEIYFKPEKEGHQYASDLVDQIECLNHGKYLDEELQNSAPTDFCVGVAGY
PEKHMEAPSLDSDIHFLKKKIKKGADYIVTQMFFDNQKYFEFVDKCRAEGITVPIIPGLK
PISTKKQLNMIPHRFKVDLPDDLIMAVVNCKNNQQVREVGVEWCINQSKELIIKGVPFLH
YYSMGKSDNIKNIAKEIF
>A0A1G0ILW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPLOWO2_02_FULL_42_14|TrEMBL
MQLSFEFFPPKTDTGLENLIHVADTLSSFQPEYFSVTYGAGGSAQTQTMNTVNQLRLQTS
QKIVPHISCVGATKNSISALLNDYQKMQIKKLVVLRGDATEIHTVNEFPYATDLIYFIRE
TTGAYFNIDVAVYPECHPQSSNLNNDLLYFKKKVEAGANGAITQYFYDANAYDYLLENCA
RLQINIPIVPGIMPITNVAQLQRFSALCGAELPKWLRNQLDSFGSDETAITQFGVDLIAK
LCEQLKRLGAPGLHFYTLNKAQACIKILEHQLLLHSHVRAAD
>A0A194UM11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Valsa mali var. pyri|TrEMBL
MDKITDKIAALPPDANYFSLEFFPPKTQMGFANLRSRLERMARALKPTFVNVTWGAGGST
SQKSLELAEICQRELGLTTCLHLTCTNMSRRLIDKALEDAKVLGIRNILALRGDPPRRAE
YMDENDEDDLGDEEEFKWAVDLVRYIRQNHGDYFCIGVAAYPEGHADESHPLGQSMEHDL
PSLVEKVQAGADFIMTQLFFDIKAYDKFETTLRQHPSGAFKDIIIIPGLMPIQNYQMIKR
TTKLSHAGIPDGLMARLDEVKRDDERVKLVGVDILSELIEQIREIKSRTPGPQGFHFYTL
NLEKAVSFILERTHLIPPETPGGEQPLADDLVAVPTVEINGSISNGSTSQHHLGVSDASR
RLSTHSSEPRNRVIISGERTPSNPEYEATQLEASRPYEPVHSRANTLAISEGEGVLGREA
TWDDFPNGRWGDARSPAYGEIDGYGVSLHMSVTQARSLWGAPSSVEDISTLFIRHLQGDL
RAIPWSEAEFNDETGTIKDQLVALNKKGWWTVASQPAVNGVKSTDPTFGWGPANGFVFQK
AFVEFFVPADQWKKLHEKLSKPEMKESIWFYAANAAGDFVSADSSSPLDQDVQEVGTNAV
TWGVFPGKEIVTPTIVEEVSFRAWAEEAFGIWGEWAQVYGKGSASTKFLEKMKGELWLVN
IIHHEYVEKDALWDLLLNA
>A0A3N6A957|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium|TrEMBL
MKSGSNLEKILTSGQFAFTGELGPPRGAHAEEVRKKAAHLKGRVDSVNITDNQTAMVRMA
SWAASLILIQEGIEPNYQMVCRDRNRLAMQADILGACALGIRNMLCL
>A5DZ35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)|TrEMBL
MSKVKDLILSLGPDEKFISFEFFSPKTDSGFRNLLARLNRLLAFNPLFITVTWGAGGSTS
EKSLDLAATCQNKIGINTVLHLTCTNTDKEIIDSALARAKANGIRNILALRGDPPRTEEY
WTPNCEFNNAVDLVKYIRQQYGDYFCIGVAAYPEGHVDGADTANQDPRKDIPYLVEKVKA
GADFIITQLFFDADKLVTFQKMLQLTPELKDIPLIPGLMPVTTYKVFTRATKLSHATIPR
PILHEFETIKNDDDAVKQLGVDLICDIIDRIDEHTNIKGYHFYTLNLEKAVASIMNQSQV
LRGVLEGPSTSSEISKNEDAIASDSEDESPKHFRRRSSVNEVARGSLSFHRQKDKKSIVD
ISRGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPSLKIHNASEAIAKWGSPTNIKE
LGQVFVDYLSGKIDVVPWADTSLSPETALIQEELFELNQKGWFSVASQPAVNGCRSNDNV
FGWGPGNGVVYQKSFVELFIPAKDWKELKPRLDDATTYYVGDKSGRIELSLFTNESTRHL
KNAVTWGVFPLKEVVQPTVIDYESFKAWNEEAFLLWLEWARCYKKNSKTYELLNSVRDNY
VLVSLIHHEYHDESALWDLLMQ
>A6TTI5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkaliphilus metalliredigens (strain QYMF)|TrEMBL
MKITKLFNDKRPVISFEIFPPKKELPISSIYGALDGLADLNPDFISVTYGAGGTGSNKTI
EIASIIKNKYEIEALAHLTCITSNKEVIQQNIKALQENNLENVLALRGDVPSDFIRREEN
QYQYGVDLIKELKGYGDFDIGAAVYPEGHIECDDVEKDLQYLKEKEAAGANFLVSQLFFD
NEIFYGFLEKLKAYKIESKVLAGVMPILSKKQVEKMIFMCGASLPAKVIRLVSKYEHQPE
LLRQAGIEYAAEQVADLIANEVDGIHIYTMNQPDIAKGILKRQKKTVTGHIDKF
>A0A7L3L2H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Turnix velox|TrEMBL
MVNENQHTGSGSSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITAHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYISGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFASSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLYWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A6P2ADZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gloeocapsa sp. DLM2.Bin57|TrEMBL
MSNKFRQAIAQKEFLITAEIAPPKGADPTHMLTVAKLLESRVHGINVTDGSRAVMRMSSL
VACVFLKQAGIEPICQMTCRDRNSIALESDLLGASALGVNNILALTGDPVKAGDHKEAKA
VFELESVRLLRLINNLNQGLDINQNPLTDGIPDLFPGGAIDPQLKSWSSLQKRFEQKIEA
GVEFFQSQLITDFDRLDKFMTQIASSYGKPVLAGIFLLKSAKNARFINRYVPGVDIPDST
IERLEKASDPLWEGIKIAAEQVKMAKDICQGVHLMAVKKEELIPQILDLAGI
>A0A398AVC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peribacillus asahii|TrEMBL
MEFRKELKQRILIGEGAMGTLLYSRGIDNCYEELNCTEPDQIEAIHRTYLDAGADILQSN
TYGANFHKLKRYGLEDQVSQINRQGIAIAKKVAQGKAFVFGTIGASRSIRKSDLSLEEIK
RSFREQLYSLLLESPDGLLFETYYDLEELETVLKIARQETDIPIITNVTLHELGNLQNGV
QLNEAFKRLEQLGSDVVGLNCRLGPHHMIRALESVQLPSNAALAAYPNASLPEYVDGRLV
YDAAPEYFGSSALQLRDQGASIIGGCCGTTPQHITAMKAAVGDLAPIVEKKMPATKVETI
EVREQDRTPALYEKAKTERTILVELDPPKKLGIEEFMKGSKALKEAGVDTITLADNSLAS
PRISNAALGMLIKSQLDLNPLVHITCRDRNLIGLQSHLMGLQTLGLNEVLVITGDPSKIG
DFPGATSVYDLSSFDLISLVKQFNEGLSYSGQSLGQKTNFKIAAAFNPNVKYLDRAVQRM
EKKIECGAHSFLTQPIYSTSQIEEVYEATKHLETPIFVGIMPLTSTRNAEFIHNEVPGIK
LPDHVRRAMAAAGNDPIQAQKEGVAIARELVDAAMDKFKGIYLITPFLRYEMTAELTRYI
RTLDQTKTSEVAAYE
>A0A2G6VRV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 11|TrEMBL
MKVTQHIEDAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQYFIPKQGGNDFAVDLVKQINQLNCGKYLHDVMDIDNKANFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVKRHLQVLPQIFRIDLPEDLIHAVDQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A5B7TCF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caloramator sp. E03|TrEMBL
MLIKDIFNQKRPVISFEIFPPKKEYPISTIYETIEKLKDLNPDFISVTYGSGGGNRDRTV
EIASTIKNNYGIESLAHLTCIASSRNEIQEILHHLKNNGIDNILALRGDLPKDLDSNSCM
SYMYAKDLISQIVKMNGFCIGAAAYPEGHIESENLEEDVKYLKEKVDAGADFLITQLFFD
NEMFYNFKDLTVKYGINVPITAGILPVLNKSQILRIITLSGASLPKKFIRILDKYEYSPK
ALFEAGIAYATEQIIDLLSWGVDGIHLYTMNKAEVAIKIIDNISEIKNALNQVNFA
>A0A0Q9RWQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Soil796|TrEMBL
MDQQSPRGIGQLIREGERSFSFEFFPPKDEAGEAQLWQAIRELEPYRPTFVSVTYGAGGT
TRDTTVAITARIARETSMVPMAHLTCVGHTVDEIREVLKSLTESGVRNVLALRGDPPGGP
GTAWEATEGGVNYASELIGVIKEIADVSVGVAAFPEGHVDAASLDDDVAVLRAKQDAGAE
FAVTEMVLRAADYFGLVERARATGVEIPIIPGVMPILNINSMRRMVELSRRELPTEVVDR
LRPFEEDPAGLRAEGIRIATELCEAMLDGGAPGLHFYTLNRSKATREIFEGLRITV
>A0A0L6JMW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933|TrEMBL
MKIIDLFNSKKPVVSFEIFPPKLDTPLDTIFDTLEKFKALGPDYISVTYGAGGSQKDRTI
EISSNIKNSYNIESMAHLTCVGHSIEEIDYIVDSLIKNNVKNILALRGDPPADQPDFNFD
NNGFKYASELISHIRKRNNDLCIAAAAYLEGHPECLKIKDDMINLKHKTDAGVDFLVTQL
FFDNKLFYEFQERAAIVGIKCPVTAGIMPIFSSKIKAMTAKSGCSIPAKLVLMLDKYQDN
PDDLLKAGIEYASIQIRDLVDNSVDGIHLYTMNRPKSSAEIIKNCGLL
>A0A2S6SL58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha5_Bin9|TrEMBL
MFMQPSSTFHNKLLKKNFVFTAETTPPDSSDKNVLLKKISSLKDIADAINVTDSPGANVH
MSSLVASIILAQNSFEPILQFTVRDRNRLALQGDLLGAAALGVHNILCLSGDDPSNGDQP
QTKSVNDIDSLGLVSTANMMKDKSQFPSGRKIDPPPYFFIGGAEVPTEGKPDPKKIKTKI
DNGVNFFQTQYVFDHIVLKEYMKILEDEGIFEKAFFIIGLGPFSSAKSAKWMNDNLFGVN
VPDKIINRLNQSKDPLDESMKICLELIDLFKGINGVNGVHLMGPNKENIIAEIIKNSKKN
>A0A2D5VGI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MNGNSFQDALDSDGFVVTVELMASQNDGLENFHRFLDEYQSKYQRKPKYPEIVAISVPQS
PGGLPTIDPNTVLSEIKSEFPDSLDAIAHVSCKDRNRNGLEGHLRDLRRTGVTSLLALTG
DRPVESKPIFELESLSLLDLIADLNAQTINHTSPDELDQVHQFFTGAAVNPYKYTLASAW
QQYAKAVKKIRSGANFLITQVGYDTVKSAELIRYLGAHDFTTPVLGNVFLLTKTAVERMY
ASCDQTSVDPQQKSHDLPGTYASKELLEQVSSEWKTRARGKKAMLERAAQQTAFFQQAGF
KGVHIGGFGLTFDDVDQIIDQSQEIRHHQEVETYQDNIHFPSPASECFIDSDGEFILPAA
APKLGFKQRMMGMTHNHLLSFAGETTNSGKNPEGSFKLRIVHRIERATKSVLVNCQNCGD
CFLPENYYAVCNESACVKGLVNLPCGDSNAVTGVCGHDQSAVCAGELVFEAASAVGKLDH
LSQQTNPPKVAELQGTSAVKNYFSGIDHRGRVDGKVPSKKPINLIEIGESLHAQIPRVNW
SMNNLIKQDQLNGSLAFLSGVINRQISVGVEYIAINVDDFPVEVRSDLMRKYVGLVSTLS
EPINGLPVCIDSSDPVTKRSGLEAYYQTAMDPEAKLPIVNSINIIEPEPILNLKKDYNFN
VIAMLHDRVDKDGNPKNVETVDEVHQLARQLFDRLLVHGFKPDNIFFDTAVIPIATDVEA
AFTYKTLNGIKKIMTDPEMSGVHTVIGLSNCSHMMPNRIAINRAYLEVAMEFGLDTAVLD
PTISYGLKPPGKQITGIIRDLAQNDGSDPIKGFEIFERVANYSRKYGKAS
>A0A7L3VCK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Molothrus ater|TrEMBL
MVNETQHSCSASSSSRSDGGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGD
KWFSLEFFPPRTANAAVNLISRRVLQAGGPLFIDVTWHPAGDPGSDKETSSMIIAYTAVN
YCGLETILHMTCCNQSKDDITGYLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAIDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVYAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVRALLKVLRRYELRVNY
HIVNVKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A5R8YJU1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbispora fusca|TrEMBL
MALGLPSRLPDRVPTVRELLAAGERSFSFEFFPPKTDEGERQLWRAIRELEALRPTFVSV
TYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHLVGRFADAGVRNILAVR
GDPRGGDPMDEWVRHPEGVLYAEDLVRLIRQAGDFCVGVAAFPYKHPRSATVESDTRYFV
QKCRAGADYAITQMFFRAEDYLRLRDRVAAQGCDTPIIPGVMPVTQMSTIARSEQLSGAP
FPPEVAERFAAVADDPVAVRRLGIEHAAEMCRTLLDEGAPGIHFITFNRSSATREVFQAL
HGVPAVAG
>A0A2E9FA71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
METWQKPSFRSLLQETSTFVACVELVNSRGIITEREGTRVLKLARELSQHPQIHALCMTD
NAGGNAMLSADTMGTDLISRGQEVVIHLSCKDWNRNGLQSQAWKLASEGFDNVLALSGDX
PVSGXKGQASAVFDIDSVGLLKMISEMNTGLEVXVGQNKKKXVLKRTRFFSGAVVNNHKR
YEREVMPQYFKLXXKIENGASFIVNQIGYDARKQDELLKYMNWSGLHVPVLYNVYVLSLT
VARFFHANNIPGVTVTDDLLALVVKQADSADKGKAFFLEFAAKQCAIAKGLGFRGVYLGG
HLKASDYKRVLEIADQFGEDDWQDFAKEICFSQTDEFYFFEPDIATKLSSTEVNREYLHS
KHLKASQVSRQNVPLSYKINRTIHDIAFKKGTVGFGLGEKISRAIERKNKGAQKIFHGLE
QTFKIAAFDCQDCGDCSLPDIAFLCPESQCAKNQRNGPCGGTKQGKCEVGEKECIWSLAY
DRLKAYDQEEPMLDGPVVFRNGALKGTSAWINTFLGRDHHGKDKK
>A0A2D6RZX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MSKKSFLKELGSRILVCDGAFGTQLRKRIPSYVXCLDACNIDSDYLYIVQDIHREYKVVG
VXXIQTNTFGANAKKLEFYGLEEQVREINAAGVRLAREVAVEDIFVAGSVGPIETSPFSN
EFSVEEVSSAFKEQMEVLVEGGIDLIMLETFSDSREVEIATQLALTYGLPVVVQXRGMPG
XKLSDGTDICVFXRQMENLGVAAVGINDRPPHEVVEILKKLXKXVNLPIIVQPDAGAPRM
SQGKLLSEEYTVAPHLYGEYVNDFVKLGANIIGGCCGTTPEHIQQIKLVTKGIAPTEREK
QVFVFNDVPKPFKSKFDNNPIQQIXDEKDAIISVEMRAKTFTQFSAMIRESKNLAKAKID
LFDXPDNAGATVNIGAIGTAFRLQQETSVPTIIHWTTRQRNLISTQSHLLEAWALGVEGI
LALSGDHPKVGRFETARIVADLKGSVQLIELITRLNDNQLINGTSIGEPCNFYIGAGFNI
AEKLENQVKHLTQKVKNGAQFVYTQPVYTLDDIERTYEATKHLGVKVLYGIMPITTPRSI
PFLRDNLGIYIPRSIVKQFSETSDAMSTRFGLEMINNFAYNLSQQNRVPIDGIYIIPPSN
VNWKNKRKAVIDIIEAYRGQIVVE
>A0A496B689|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Poribacteria bacterium|TrEMBL
MTTTLRKKDNFMESLAHQILVCDGAIGTELRKRIPAYLQCVDACNISTEHAEKVMAIHRA
YADAGADVIQTNTYQANREALAVHGLAEQVEEINKTGVALAREAVSETTYIAGSVGQIPF
HNLDTPVPSTKTIRRIFKEQMDALVDAGVDLLVLETFVSPKQAETATKQALTYDVPVVVE
ISGVSGGTVGAGLDVRVFAQELEQLGAHAVGINCRGPHDLVEAMELLAPVIKVPIAVQPN
AGNPRVEQGEVAVSYTVEAEVFRDYVGKLVELGANMIGGCCGTTPAYTAKIRQAIAGREP
VERESRIFVLPKIRSVEGSSLGVSSRSPRPYDNPVQQVFETRERIVSVEMRANTFPQLRA
MLKEAKGLAAIGADLFDVTDNSGAAVNIGAVGTAYRLQQATQIPTLIHWTTRSRNLISMQ
SHLLEAEALGIRGIVALSGDHPKAGPYETASLVPDVRGAVQLMKLIARLNQGELADGSSI
GEPCGFYYGGGFTIAENLQPHVKHLANKVAQGANFAYTQPVWTYEDIVRTQQATEHLGIK
ILYGILPLTSFRSASYLRDNLGLYIPQFIVDKFRDLEDAAGHELGMRLTLDLVRDIRNQN
QCKIDGIYLIPPARMNWKNRASVISEIVKIYR
>A0A1H0JLL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lutimaribacter pacificus|TrEMBL
MRTPDVSFEFFPPQTLEASFRLWDTVNVLAPLGPRFVSVTYGAGGTTRDLTRDAVATLHK
TSGLNVAAHLTCVNASRDETLEIANGFAEAGVNEIVALRGDPPKGSDGFRPHADGFANSV
ELIAALADTGKFTIRVGAYPEKHPDSPDTAADVDWLKRKLDAGADEALTQFFFESDTFFR
FRDACQKAGIDGDRLTPGILPIENWKGARGFALKCGTSVPGWLDDAFDKALRDDRADLLA
TALCTELCSELIEGGVKRLHFYTLNRPELTRDVCHALGVTPRVQLENVA
>A0A089P9G9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorococcus sp. MIT 0801|TrEMBL
MKSKLQNRLESGLSAVTAEIMPPRGGNTALALSKAIKLKDLVHGFNVTDGSRAIMRMSSL
ALCKLLLEANLEPVLQLSCRDRNRIALQAELLGAHALGITNILCLTGDPVRVGDQSQAKS
VQDFNSIELINQVTSLNKGIDPVSDLLPDGPTDLFAGAAADPNCRGFDGLRRRIELKKNA
GANFLQTQMVMDPKVLERFCKEITEPMKIPVLAGVFLLKSSKNAQFINRVVPGACIPESI
ISRLESSSNPIDEGISIAAEQVKSFLGIAQGVHIMAVKAEQQIPMILDRANIN
>A0A2T5ASZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. VMFN-G11Ma|TrEMBL
MTRSADPDESVDSVVRESSIEVIPLKGAEEKVALVPAGTTVSITCSPRFGLSRTLDHVAA
ARRSGHRVVPHLAARMVEDRRHLRDFVRKVNDLGVDELFVIGGDGEEPVGAFTEAADILR
ELGEFDHELSRIGVGCYPEGHPKISDEALLDALRRKQQYAHYMVSQLCFDAHALAGWLRS
VRARGVTLPLRIGVAAPLQIRKLIELSIKIGVGRSVRFLSKQHGLVGNLLLGRSYEPLDF
LLALQQEMSLTEFTVEGLHLFSFNQVQTTLEWLSRADGAEKAG
>A0A5C6GM53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium rileyi|TrEMBL
MHIKDMLVEAEKGGQPSFSFEYFPPKTAQGVQNLYDRIDRMYNFGPKFIDITWGAGGGIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLDKVNDALQRAYKAGCTNILALRGDPPRAQEK
WTAAEGGFQYARDLVKHIRDTYGDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGKVRERGINVPILPGIMPIATYASFLRRAKHMQCKVPDHWMTAL
EPVKNDDVAVREIGKSLVAEMCRKLLASGIHHLHFYTMNLAQATRMVLEELTWAPCAERP
LQHALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPNTVQDIANIFVKYLNQELDSLPWSEAPLTGEANAIKANLVE
LNKRGLLTINSQPAVDGVKSSHPVHGWGPSNGYVYQKAYLELLVPGSIFTEMVKRVEDKP
TLTYYAVTKDGDLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESVSFLAWRDEAFRLGTDW
AHCFESETPSRILLDHIVNEWYLMNVVNNDFHDNQAIFDLFEGLEVRGLDTPLTT
>A0A0S7YSW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium SG8_13|TrEMBL
MKSNSTGRLEKILTGGGFAVTAECGPPRGADAEVVRKKAEALKGCVDAVNVTDNQTAIVR
MSSIAASTHLLAMGLEPVMQMVTRDRNRIALQSDILGAWSLGIRNILCLSGDHQTFGSHP
EALNVFDIDSMNLLRMVLEMREDGKDMSGFELKTPPRMFIGAAANPFADPFEYRVIRLAK
KIDAGADFIQTQCVYNMDRFRDWIHMAREEGLTEKVHIMAGVTPLKSEGMARYMAKRVAG
MDVPEPLIKRMGAVPKSKASEEGVTICLETIAQLREIKGVHGIHIMAIEWEEIVGEIVES
AGLLPRPQPES
>F9VPZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia alkanivorans NBRC 16433|TrEMBL
MPFSVEFMPPRDAEGEARLWRAVRIFERLSPAFVSMTYGAGGSTRDRTVRITGELAAQTT
LLPVAHLTAVNHSIAELRALVGAYADQGIANILALRGDPPGDPLGEWIAHPEGVEYAEEL
VHLIDTLGDFHVGVASFPEGHHRAPDLEHDTRNLVNKLRAGAEYSITQMFFDVEDYLRLR
DRVQAADPEQGAKPIIPGIMPVTSLASIKRMAELSGSVIPPKVVERFTKAAGDGPEEDRA
TVRAVGIDFATETAERLIAEGAPCLHFCSLNFAKATSEVLGRLGVDVDAALHVPA
>A0A317RHL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium limosum|TrEMBL
MVNKMSSLLQQTLEAGKFAITAEMAPPKGTDFSHILEIADLLKGRVQGVNVTDFQSAAVK
ASSLAMCVELERKGLEPILQMTGRDRNRIAIQGEMLSAGHFGIKNMLALTGDHTTTGDNP
EAKPVFEMDSVSILQTAEVLMSGQDLAGNELQGSPDFYLGACVTPVFDPVEVQLIKMRNK
IKAGAKFFQTQGVFDIEVMREFKELTKDMDCYVLAGIIPLKSAGMAKFMNRSVPGISVPD
ALIERLTEAEDKAAEGIKIAGEFVAQLKEEGVCDGAHIMAIGAEENVPKILDIAGL
>A0A0Q6SLU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. Root335|TrEMBL
METPNISIEFFPPKTSEGAEKLRVARQKLAELNPKYFSVTFGAGGSTQHGTLSTVLEILA
AGHDAAPHLSCVGGTRESIRAILQEFKDKGIRRLVALRGDLPSGYGGAGELRYASDLVEF
IRQETGDWFHIEVAAYPEMHPQARSPQDDLQAFARKVQAGANAAITQYFYNPDAYFQFVD
NVRKLGVDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWIRLKLASFGDDSASIKAFGLDV
VSGLCERLLAGGAPGLHFYSMNQAAATTAIWQRITAS
>A0A0N1G740|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacteria bacterium OK074|TrEMBL
MALGTASTRTDHARTVRDMLAGGKATYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNILAVR
GDPPGDPMADWVAHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFRPESYLRLRDRVVAAGCDTPVIPEIMPVTSVRMLQRLPQLSNAVI
PDALNERILTAQNDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQT
>A0A4U8SV53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. MIT 03-1614|TrEMBL
MFGFEFLPHQKSEDIQHLKAMLEGAREFLKENVGFVLIPANVRKNASVNAILSAYILREH
IDLPFVPTISAAGLDKTQILSQILSLKYANFTCVALIGGDDTNKAGSEKIDGIELIQMTR
DTLGSDISIISGTPIDTTNPITRERLAQKLRIGVDRIITQPIFCPHQASKFIRSFQELKS
ESKSVAELSLGVFGIFSLQSVRAINEANLGFEVPKSYIEQMQGEAGQEDCNASLVAFRHL
WENLQKVAKQNDVCLYLSTPKHNDLRAYGVQMSEG
>A0A560WXX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. AEW013|TrEMBL
MSLPSIHPNWDLPPKGMTDGYSLEITAKDIDALREAAPAMAPETPVAVTFLPGESLEARI
EAARTVRALGFEPMPHFSARRLESGDDFEAYLAAVVREAGVTRCFIIAGDPPEAAGPYSD
SMSLIRTGAFERAGIKAIGVGGHPEGHPNMTPDQCFDILIAKCAEIEARGMAPLIVTQFS
FDAAPVLSWLEELRGRGIDAPVRIGIPGPAGIKTLMRFAARCGVGASASVLTKYGISITK
LIGTAGPDKLVDALGKGLGSQHGKVRLHFYPFGGLARTVEWINNYTKSR
>A0A0Q7SXR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. Root1455|TrEMBL
MTVSAPRRVLGPVARAGERTDRPRVSFEFFPPKTEQMEENLWSAIKRLAPLDPAFVSVTY
GAGGSTRERTHRTVKRILAETSLKPAAHLTCVGASRAEVDEVIREYWESGVRHVVSLRGD
PPPGEGGIGGVYVPREDGYKNATELTAALTSIAPFNVLVGVYPEKHPESPSIEHDIEVLK
AKIDAGATLAISQFFFDTDAFLRFVDKVRAAGITIPIVPGIMPVTNFKGLLKMSAACQTA
VPGWLANIFDGLDEDADTRRLLACSVAAEMCAKLQEQGFGDFHFYTLNRADLVYAICRVL
GVREAAPAPSEAAA
>A0A231HVB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTKINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQFIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPNFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKETIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7K3LZ26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytoactinopolyspora mesophila|TrEMBL
MPSGDAPPQEVRRLGPLHGVAGIGERGTSESAGRGEVPIDGPPRAGVFPDGLSLLKAIDA
SPYRFDEIGVPSYPEGHPNIDDDTLWSTLVAKQDYATYTVTQMCFDADLVRRFAIDARAH
GVTLPIIAGIPGAVAAAKLLRVSFRIGVGDSVRFVRRHRAVARRLLRPHSYRPDALLRKL
VAATSDDAAVADEGQGRRHRRPATTRSPLVAGLHIYTFNEIAPTVRWLEQRRRSLSSGEE
VAADDHAV
>A0A2C2UU47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKILDLLSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADLIQTN
TYGANEAKLRMYGLENRVAQINKAAVKLAKAAVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEKVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQLALHEAGTTQNGN
DVNEVLKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPAHIERMKRAIANVTPVTEKQIVQKQQVVH
MQTKRASTHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADVITLADNSLA
SPRISNMAMGALLTKHDIPVLMHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRMDGHETQGAAVEEGIRISQELIDAAMKYFNGIYLITPFLKYEITENLVKYVK
EKQEMKEGIY
>A0A420GRB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus toyonensis|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPLFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A855BM54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKIAKASVTERNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTLKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKSHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDTGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A853ZCG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTDIPIVAQLALHEAGTTQNGN
DVNEILKQLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVDGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIKLIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGICISQELVDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A0J7FU38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTVQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSVLGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A1S9UA13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus|TrEMBL
MKLLDLLSKGVVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTERNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPNFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKTKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A523TMC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MPSQNLFNEWLASGEIILADGAMGTILHSRGISFNVCFDDLNLSQPTLITDIHRAYLEAG
AQIIETNSFGANRYKLAEHGLEQRVAEINAAAVDLARQAITASDNDSLVAGSIGPLGVRL
APFGRVKPEQAYDAYYEQIEALIQAGADLLIFETQNDLYEIQEAIRAARAISDLPVIATL
TFTRDDRTLLGDSPRRVAQVLVESGAQVIGANCSGGPAQLMRVLRQMRAAAPEARFSVMP
NAGWPERVAGRIMYPATADYFADYAIQFCQAGASVVGGCCGTTPEHIANMRAAIDTADKP
RLAPEPLLFKSTASPAGPSEHPPTELAARLASGQFVISVEMDPPRGFSTHKLLAGAHLLA
EAGADVINVADSPMARMRMSPWAVCQLIQRDVGIESVLHFPTRGRNLLRVQGDLLAAHAV
GVRNVFVVMGDPTAIGDYPDAMDNFDLVPSGLIKLIKQGFNTGVDHSGADIGEATSFFVG
TALNLCSQDPERELRLLHKKIAAGADFILTQPVYLPDLASSFIDSYRERFGELPIPIIVG
VLPLYSKGHVAFLHNEVPGILIPPQIQRRIEQAGDKAANVGVEIAVDLLAELRRSVQGAY
IMPPFSRFDLAAEIIEGIRDVKPS
>A0A4D4JZ47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces antimycoticus|TrEMBL
MALGTASTRTDRARTVRDLLASGEQSYSFEFFAPKTAKGEQTLWNAIRRLEAVSPTFVSV
TYGAGGSSREGTVRVTERIATDTTLTPVAHLTAVNHSRADLRNIIGQYADAGIRNMLALR
GDPPGDPTGEWVRHPDGLNYAVELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDIRHFID
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCTTPIIPEIMPVTNVKQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIDYATEVCARLMAEEIPGLHFITLNHSPATLEIYENLG
LHQRS
>A0A4R0TAB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWEDDIQSLRTAGIL
YASEQIADLVAHGVDGVHLYSMNHPATTRRIWRNVEPLFLGTQG
>A0A2T1NE98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantibacter aestuarii|TrEMBL
MKVTDHIKNAKGKTLFSFEIIPPKKGNSIQELYSNIDPLMEFNPPFIDVTTSREEYIYID
REDGLLDRKITRMRPGSVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMSHQKYFEACDGGHHYAKGLVEQIQNLNKGKYLHDVVEASSPANFCIGVAGY
PEKHMEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVKKAKDFGIDVPIIPGIK
PLATKRHLQLLPQVFKIDLPEDLITSVENCKDNKAVRQVGVEWAIQQSKELQQAGVPVLH
YYSMGKSDNVKAIASKLF
>R5GNI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacterium sp. CAG:786|TrEMBL
MKIPELFKDGHTVFSFEVFPPKKDNDVSVIYDTLEQLGDLHPDFISVTYGAGGTAAGAST
IDLVRRIKEHCRTESIAHLTCVNSTHADIDEKIKELEANGVENVLALRGDINPNIPPKHE
FLHASDLIEYMKPRSNLSFSGGCYPEVHPECTSMVDDIHNLKKKVDAGASHLISQLFFDN
GSFINFLEKARIAGINVPIEAGIMPCTNAKSVQRMVTMCGASLPLKFTKMINRYGDNPEA
MRDAGIAYAVDQIIDLIAQGVDGIHLYTMNNPYVARKISESIEKVIRCDK
>A0A2A2WT61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia natronolimnaea|TrEMBL
MDRIASSRTPRVPFSVEFYPPRDEAAEARLWRAASVFSELGAAFVSVTYGAGGSTRDRTV
KVVERVVRETDLVPIAHLTAVGHSVAELREMIQMYVDVGVTNILALRGDPPGDPLGDWTP
HPEGLHYAEELVRLIHEVGDLHVGVASFPEGHYRARDLDHDTEILLNKLRAGAEYSITQM
FWDVEHYLRLRDRLESADPEQAVKPVIPGLMPVTSLRQVRRMVELSGCALPDGLSGRLRT
AAGDGPDEDRAAVREVGIEFATELCERLIAEGVPCLHFNTLNFSRATHEVLANLSMVPSP
DVVASGV
>A0A523YWM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineales bacterium|TrEMBL
MAEAQSNGYKSGSRLERILRDGHFAVTGELGPPQSSNGDVIREKAKILLGFCDAANITDN
QTAIVRMSSIGAGTIVVQEDLEPIIQMTCRDRNRLAIQSDLMGAYALGMRNVLCLTGDHQ
SFGNHPTAKNVHDLDSLQLLQMMVGMRDEKLFQCGDEIKGVEPRFFLGAAANPFGDPFEY
RPYRLAKKVEAGADFIQTQLIYNMPRFEEYMEKVRELGLHEKTYILAGVGPLKSPGMAKY
MRDQVPGLDVPDEIVDRMTAAAKGIDKEDKKARRDAWRGEGIQITIELIQKMRDVEGVSG
VHVMAIEWEEAVKPIVEGAGLMPRPQVTAQPSASTETGE
>A0A1H3LYN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharopolyspora shandongensis|TrEMBL
MTRVIDRLRPGKTVFSVEFFPAKTDEEERQLWRAIRELEPLDPAYVSVTYGAGGSSRDRT
VRTTGRIASDTTLVPVAHLTGVNHSIAELRHVIGSYAAEGITNVLAIRGDPPGDPMGEWI
PHPEGITYADELVRLVRECGDFSVGVAAFPHLHPRSVDLESDTRHMVNKLRAGADFAVAQ
MFLKPEDFLRLRDRLAQHGCDQPLLPGIMPITTPRVLGMTTQLSNMTIPDEVSAVLDPLR
DDAAAFRAAGLEITTRLCEKLIAEGVPALHFYSLNRAKATREVVANLGLADGVLKAA
>A0A7C3FTT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MPVSFKEKLDSGKFVITSEIAPPKGTNLEQMHHHIQMLKDKVDALNVTDHQSSVMRFPSI
GGCMAIREHDGEAILQMTCRDRNRMSLQAELMLAYTRGIRNVLCLTGDAIPVGDHKEAKG
VFDLDSVQLLRTIRTMESGYDLGGNELDGVVEFCSGAIVTPEANPLEPQLIKFEKKVEAG
AVFFQTQAVYDLDNFVSFMRYARRFPVKILAGIVLLSSARMARYMTENVPGIFVPQNLID
ELSSAPKGEALTKGIEIAGRMIATLKKDAICDGVHIMAIGKEEVVPDILAAAGM
>A0A7X9D0Z6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp|TrEMBL
MLGKKILSRQSGIIVYGITPPKKDTSPERIEALSKKQVERIGALNVDGLVLYDLQDEKDR
NPNDRPFPFLETLDPMYYSNKYLGDLKIPKIIYRCVGKYTAAQFPEMIAPTNGQNDFSVF
VGASSREQKVFLRLSEAYEIYQNMTHRPTLGGVLIPERHMIKSDEHLRIISKMEKGCKYF
ISQAVYNLEASKNFLSDYYYYCKSENIEMVPIIFTLTPCGSKKTLEFLKWLGISIPRWLE
NDLKNSKDILSESLSLCKSIFGSLLNFCIQKKIPIGCNIESVSIRKVEIEASITLAKDIK
NMMGQL
>A0A800EGA3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MVVTQQPSYAKESFDLSFELFPPKTAESEAMLWQTVDELMGFEPTLITCTYGAGGSTQTK
TLEVLDGVLSRYPTVAVASHLTCVGRTKDQLREYLYEAQQRGVASIVALRGDPPQGETTF
TPIANGLHYAAELVALIKEEFPEFGILVAGYPETHQEAVSPEADLEHLKEKCNAGGDTIV
TQLFYDNSDFFRFRDRCSSIGITKPIIPGLMPVTNFKQIKRIATLCKARLPNSFTQALEK
AGDDADAQFEAGVDYASKQAEELLSDGVPGMHLYVLNKSPAAIRVLEQIGMTRP
>A0A800A338|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MATRFKEVLNSGKFIVTSEIGPPKGTNLEKMYHHIDLLRDKVVAMNVTDHQSSVMRFPSI
GGCLAIKERGGEPILQMTCRDRNRLALQAELLFAYTRGIRNVLCLTGDAVPVGDHKEAKG
VFDLDSVQLLKAIRQLEAGRDLGGNELDGTVEFCAGAIVTPEADPIEPQLVKFEKKVEAG
AEFFQTQAIYDLDNFSKFMKFARQFPVKILAGIVLLTSARMAKYMTENVPGIFVPQSLID
ELAAAPKGEAVNKGIEIAGRMIAALKKDFICDGVHVMAIGREELVPEILTAAGL
>A0A6L5K755|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKIGDIIQARGSSLSFEFFPPKDAAAEDRLFQTITTLKGYEPTFVSVTYGAGGGTLRNTR
KVILRIKEATTLTPMPHLTCVEQSHKDLDNILKDYKSHGVENVLALRGDPPRGSDKFVAH
PDGYCYAIDLVRLVVLVGGYSIGVAVYPEGHTEAPDLETDMYYTKQKINAGADFAITQMF
FDNRFFYNFMERAGKAGITIPIIPGIMPITDIEKIKRFSKMSGATLPRSIVEPMEKAASP
EEARKLGIEFATRQCEDLSQNGVNYFHFYTLNQSQAVTEILTNLGFANK
>A0A2D6NAB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MGLVRIAESLHCALPPIRDSVQRLVSDDSLAQYAGEHHLIHTIHAQVAAGADFLDVNVDD
LGAAGRFTFEQTVAALHRVLALVVEHGAGIPPCIDSSDPRLLEAGLRFYYSASRSGDAPG
TLRPPLLNSVIASRLDLLALRAELRFSVIAMLLEKVDKDGQPFEHSFTEAAPAEAYWETA
RYLFLKCREAGFAPGEIFFDPTIGPLGADYVGYTRQTFEGIRRIKDDPELAGSHISIGLS
NCSDGLPRRQSLNRAYLRVAQDYGVDAAVLDVTGVTGKERVHPWSLRLVRRVVSPKGGDP
AAALEDLADYCAALPRPTTPSVTEPVRNTLAETLATPDGVVYTVELVPSVGDPDELYRFA
EQARDSEIIPSITDTAGGARAPSPEMLGVELARVLDRQPIINISCKSEDRDGLIKRLTSL
HQHGLRNVFAVTGDYPRDGRAVFDLDSVGLLLATWALKAGLDFPSLLPRRGGALPDLYAG
AVASPFKYTEGDVWAQRVKLWKKWRAGASF
>A0A3B9VQV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
KEAPAVAAGDILLSAMPNAGGFERIGHRFLARANPEYMGTLARQLGDSGASLVGGCCEVH
PEHIREMSAYLKSRTSSLEQDSAGPAARPGTLGNTGTGSVPVAAIRDKSDSRRANGEFSR
KLFEGEFAISVEVVAPLGAESKALDLRATMVSQVVEEGLADAVDITDGSRGMPLVPPGDL
IELIRQKLEWRYGDRIEFIPHFTGRDLSTLAVQSRLMGYHWRGIKNVLFITGDPPKMSPT
YPRSTAVFDMNSVQMIRATASQLNQGRDFGGNPLGSEFASSAGFTVGTGFEPEAINMPRE
LDRLRAKIDAGADYVMTQPAFDNSPLSTIEPVRNLIPVLPGVLVLRSADHAKRIAQVPGM
NLPAGVLDEMDRFSEPADQAKAGLDLAVTRARAYKSEGWAGLYLMSPASMGAAVSVLKAL
AE
>A0A3N5XMB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MKSSNEHISKDANFLERPRFELIPMKGVEDQAQFLPDGATVAVTVSPSKGLDATLKLAET
LAGRGFNVIPHLAARLVRSREHLEELVDRYEEDGFAELFVIGGDETEPSGPYHSAALVLK
DMQEMPNRPKRIGIGSYPDGHPIISKDELFNALQEKQPMVNYMITQICFDQKKITSWLGD
MRRRGINLPVYIGIPGVLKRQKLLDISLKVGVGDSTRFIMHNLGLAARLLGSEMYTPDKL
VKQAVSMSGDKVNGIAGFHIYTFNQCQTTEQWRQKCLKA
>A0A419DCT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MDIKASNTASDHNKFKSALLNKDTFCITWEQVPGRGASEKERETILQNSELAARGGRIHA
ISVTDSPGGSPTFSSGTLGIEIRKLGIESLVHLAMRDKNRNEIESLLYGLAAVNVRNLLV
ISGDYPARDGFEGRAHPVFDLDPTHVMQLIDRMNHGLKYESMGKTITLAPTDFFGGIAVS
PFKQLESELMCQYYKLDKKIRGGAGFVISQVGYDARKAQELILWLKEKGYEIPALANIYA
LSYPAAKLMNENKIPGCVVTDKLLAQLEEERKAPDKGKSARLLRAAKMYAIARGLGYKGA
HFGGHGMTYDMMEYILQKGEELYPKWPELVAEFDYPQPDGFYLYEKDTKTGLNTDKASKR
PFKGRKTLLTGFSRALHEIFFNPQHPLFKPSQKVFQTIDSSNWMRKTFEFLEHQGKGVFF
ECLRCGDCSLFDTGYLCTTSQCPKGERLGPCGGSFQGWCEVYPGKRQCVWVRSYTRLKAY
RDEDKLCTFVIPPRDWELWQTSSWINFYMGRDHTAKRLGVNPPIKKAKKARPDTNSA
>A0A8C8C7Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oncorhynchus tshawytscha|TrEMBL
MVKSDSSGASNSGCESSKESSRSSTPVLDTDRTDRLRDKMRRRTESGDHWFSLEFFPPRT
ASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLT
CCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEEEEAGFNYATDLVKHIRCEFDDY
FDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIITQLFFRADTFLKFVRDCRAIGIT
CPILPGFVFQGYQSLRQLVKLSKLEVPEEIMQVIEPIKDNDAAIRNYGIEQAVGMCRVLL
ESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTLPWAVSAHPKRKVEDVRPIFWASR
PKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLKMWGEELTSEQS
VYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLLKDELDKVNRRGVLTINSQPSING
KPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVNVHGQNTTN
AHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEAFALWIEQWAKLYEDESPSRMIIK
YIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPPEEQPAEQTAEQPNDEQSDKEQPG
K
>A0A7C0UUW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MGFRQALESGKFVVTAEVGPLKGTDTSEVNEVAELLKDKVDGANVTDQQSAVMRLGSLVT
SYLCIQKGLDPIYQLTCRDRNRIALQSDLLSAHVLGVRNVLALTGDFPTFGDHPDAKEVY
DLDSVQLVWTIKRMNEGYDIAGNELQGKTDFFIGAVVTPYTDTEEAFELQLIKMEKKIEA
GARFFQTQAIYDVDVFEKFMKRAEKFGVPVLAGIIPLKSVGMARYMNKNVAGVFVPDHLI
DELKRSDDKLAKGLEIAARLIKDVKDLCQGVHIMAIGMEKKVPEILELAGLA
>A0A7C0VKS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MSLRSKLEAGEFSLLAEIETSKGIDVLSMVANARQVKDKVTAFVVPEMSNAVMRMSALGG
AMVLQNKDMETVMQVNCRDRNQLALQADLLAAGACGIVSIIAVNGDDPSVGDHPQAKAVY
DLEPCELLQAARELNNGSDLAGNPLSGATNFLLGATANVCCEGETLEREVEEVNKKIAAG
AQYIITSPVFDLESVENLASTIDCQKKKVIPTVLLLKSVGMARYISQTQEYISIPDSIID
RIRKSSDKAGECIRIAREMIAALEAAGFGGVLISTVGWEHKLPEILL
>A0A2M7SDE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desantisbacteria bacterium CG_4_10_14_0_8_um_filter_48_22|TrEMBL
MKLTELIKKKNFVVTSEIGPPKGWQVEHHLDEAKKYFAGIVDAVNVTDNQSSVMRFGSLA
TCHMLKDRGMEPVFQVTCRDRNRLALQSDILSAAGLGIENLLLLTGDHPKLGDHPGSKPV
FDLDSVSLTHAVRQMESGVDLAGNKLDGDPPKFCKGAVVSPCAEPLEPQLMKMEKKINAG
TEFFQTQAVYEPEKFARFMEKIKGWNVPVLVGIVILKSVGMAKFMNENVAGVFVPDPLIE
ELRKDKEKTKSGQTGVEIAARLIKEMKSMCQGVHIMPLGWDQHVPAILDAAGL
>A0A2R7M467|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. HMWF026|TrEMBL
YGPCGGVGFDGSCEADAGHLCAFLPRPTVPWTGLDRTTDVAPAARTAAAAQTLDALGTRP
WVVADLPARALSVASIDRSAAILAGEVDAVLAGDAGSARVQFPPAYRAHLLQRRGLRVWT
GLNMRDRNRVAIEGELAALAVEGVAGVHCVTGDHTLAGHRPDATPVFDLDSTEATALARA
AGHVVSVAASPAAPPVDRRAARLCEKIRAGADVCFINHAGGAAPVRRFVEEAGDGIRYIP
CVPVVVDHASADLLESFTTLALPEGFVERVRRSRDPRAEGISLAVEMAQQMLAVPGVVGV
NLSGGREGAEESFAEALAEIARRLR
>A0A3D5G1W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MISSTRRLPLVSFEFFPPRTSHAARTLWRSFKRLEPYGPRFTSVTYGAGGSTRERTHQIV
QRMQEETDVPAAAHLTCVGATRDEVDQVARDYWEAGIRHIVALRGDAPAGSDGYHPHPDG
YHYASDLIAGLKRVVDFEISVAAYPETHPEASNADADLDNLKRKIDAGATRAITQFFFEP
DLYLRFMDRARAAGITAPIVPGILPVVDIISVSRFAERCGASVPDWLVSRFGRVGSGTQA
RSSIAVSVATEFTHRLMLEGVDEFHFYTLNRAAVVARTCENLGIVPAEAPVVTG
>A0A3D5KEE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp|TrEMBL
MLIKDIFNQKKPVISFEIFPPKKYSNIDVIYSTLEALKDLRPDFISVTYGAAGSTRDKTV
EIASIIKNKYDIEALAHLTCIGLDQEGLDKIIGELIKNNVRNVMALRGDLPEGMDKKELD
SSSFAHASDIIASIKKHEDFSTGGACYPEVHPECESLDKDIENLKLKVDSGADFLVTQLF
FDNDKFYNFMDKARKAGINVPISAGIMPVTNKKQVERMISLSNXEQIIDLLSWGIDGIHL
YTMNRPETCRKIINNITSIRESLERK
>A0A1F9A1Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_43_22|TrEMBL
MKSGSQLEKVLTGGHFAVTGECGPPRNANPDIVRQKAAHLRGMVDSVNVTDNQTAVVRMS
SLAGCLILMQEGLEPNLQMVVRDRNRIAIQSDILGAYALGVRNMLCLSGDHQKFGDHPSS
KNVFDLDSMQLIQTVKKMRDDGKFINDQEIEFPPKMFIGAAANPFADPAEFRAVRLGKKV
AAGVDFVQTQCIYNLDRFEKFMQQVRDMGIDEKVYILGGVTPMKSVGMANYMKNLVPGMD
VPEEVINRMKGVGKKDQAKEGIAIAVETIQRLKEMKGIAGVHVMAIEWEERVPEIVEMAG
LLPRPQV
>A0A3L7AI12|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthobacter tagetidis|TrEMBL
MTDAVRASRQTDKAPISVSFEFFPPKNEEMEKQLWASIDRLAPLAPRFVSVTYGAGGSTR
ERTHATVSRIVRDTDLHPAAHLTCVAATRDEIDEVIRGYGTAGVKHIVALRGDPTTGVGT
KYVPHENGYAHACDLVSGIRRLGDFEVSVSAYPEKHPESPSIDADIDYLKAKVDAGATRA
ITQFFFENDVYFRYLDKVRAKGIDIPIVPGILPVTNFKQASNFATRTGASVPSWLLKRFE
GLDDDAETRKLIAAAVAAEQVTDLVDRGVTDIHFYTLNRADLVYAICHLIGLRPKAAEAP
QAIAV
>A0A1M5TRX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis glycolicus DSM 9705|TrEMBL
MSFSKRLTAHEFVVLAEMHTPKGVNITGLVNDARRIKGRIDAVVVPDMDNGIMRMSALAG
GVLMQQQGIEAIIHIYCRDRNRMALQGDLLAAHVLGIRNVMVTHSEEMSQGDHREAKEVF
DLNEVELVRTVGELCGGQDLSGFELDGSPDFTVGCTVAPYADEAALAGELQAAADKVAAG
AKFVITPPVFDLDHFQSFLAQAKGLGVPVIPTVFLLKSLAIAQYIARSEPGAKISEELVR
RIRKSSDREAEGLKIAGETVAALRDMAQGVMLQTLGWEHKLPIILDHAGL
>A0A218QC56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolypothrix sp. NIES-4075|TrEMBL
MLDTSNTAFTCFRQAAKAGDFLITAEVTPPKGGNPTHMLSMAATLKGRVHAVNITDGSRA
VLRMSSLVASAILLQNGIEPICQMACRDRNRISLQADLMGAHALGIYNILALTGDPVKAG
DHTDAKGVFDLEAVRLLQVIQKLNRGFDCNEKPLTDGSCDLFAGAAVDPQCASWSGLQSR
FERKIQAGAQFFQSQLITDFERLEKFMDKIAAGCDKPVLAGIFLLKSAKNAQFINRCVPG
VNIPDHIIDRLAQAKDPLEEGMKIAAEQVKIARQLCQGVHMMAVKREDLIVPILDMAGVA
PVKQLVTV
>A0A349AMZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MHHFSCVGDSRQALAEKISEMKNRNIRNIFALRGDPPAGDENWKPAADGIEYCY
>A0A2G6D6H4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium|TrEMBL
MKTDSALEKILTAGYLAVTSECGPPRGADAEDIRKKAACLSGVVDAVNITDNQTAMVRMS
SFGASVIVKQEGLNPLLQMVTRDRNRLAMQADILGAYALGIDTMLCLSGDHTRFGDHPMA
ANVHDIDSIQLIQMVRTMRDEALFQGGAEIKKGAPKMFIGAAANPFADPFELRVMRLAKK
VAAGADFIQTQCIFNVPKFERWMAGVREMGLHKKCYIMAGITPIKSVGAARYMRNRVPGM
DVPAQLVERIGSVPKEDQAEEGIKVCIETIERLKNVEGVAGFHIMAIDWEEKVAEICERA
GLLPRPQI
>A0A2N2V773|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-10|TrEMBL
MNTEISIEFFPPQTPEGIEKLRSTRAELAKLNPTFFSVTYGAGGSTRERTFKVVKEIAAE
GFDAAPHLSCIGSTRHSIREILGEYQAAGIKRIVALRGDLPSGMAETGEFRYANELVEFI
RAETGDCFSLEVAAYPEWHPQARSPKDDLAAFARKVKAGANSAITQYFFNADAYFNFVDE
ARAQGVTIPIVPGIMPIAGFTKLARFSDACGTDIPRWMRKKFESYGDDTDSIRAFGLDIV
TELCQRLLKGGAPGLHFYCMNQSALTTEICQRLRKR
>A0A2R4GXT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodopseudomonas palustris|TrEMBL
MSDLPQQLPAISFEFFPPKSEEMERNLWQAISRLAPLHPSFVSVTYGAGGSTRERTHATI
ARILKETDLTPAAHLTCVDAPCADVDEVVTRYHDIGVRHIVALRGDPTTGLGGTYTPHPQ
GYRSSADLVASIKRRYPDIDVTVSAYPEKHPESTGFDADLDILKAKVDAGATRAITQFFF
DNDLYFRYLDRVRARGIDIPIVPGILPVQNFKQAAGFAARAGASVPDWLAKQFEGLDDDP
DTRKLVAATVAAGQVHKLAKHGVGNFHFYTMNRADLVFAISHLLGFRPQAARQAA
>A0A2S6S6B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha5_Bin12|TrEMBL
MEYQSTLHKKLSEGTFVFTAETTPPDSADKNVLINKTLSLKNVADAVNVTDSPGAKVHMS
ALTASIILAQSGIEPILQLTVRDRNRLALQGDLVGASALQVNNILCLSGDNPQGGDQPET
KAVNDINSLTLIANANMMRNEKQFPSGRKIDPAPKLFIGGAEVPTAGTPNPMKILEKISS
GVNFFQTQYVFETKTLEDYMKILEENGILEKTYFIIGLGPFASAKSAKWMNDNLFGVDVP
DHIINRLEQASDPKKESKKICIELIEQFKEVKGVNGVHLMGHNKEEVISEIINESKKN
>A0A3D5E6C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MSLDSYAASGQAGLMSFREAMESGAFPVSLEITPPRIPKKAVLLRRARLLDSRTLTVNVI
QRPDRQSSLEAALELRREGLEPIWHLTTRGRSGKDIAADVTQAQNGGLRHVLCLRGDQVQ
ESGGIAVVEAIGVIREQAPEMAIGAALDQYRGNESTDRLLAAKLRAGAGSVWTQPVFEVA
PLLRAASFVKAVRPDAHVVAMAMPLLTSESLDAISERLRIPAPEALRRRIQMGEEEAWRA
FEETLAILAGEELVDAVALMTYRADPPEGTAERLLSGLQRMGIGKAASPSTDC
>A0A523V500|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium|TrEMBL
MATPFREILRTKSFVVTTEVGPDKGSNVSKAIEHIGLLKDKVDGLNVTDNQSSVMRYPSL
GTCLLIKEHGGEPVLQVTCRDRNRLAIQADLLFAYSRGISNVLCLTGDSIDVGDHKEAKQ
VFDLDSVQLIHLVHTLNSGKDMAGNELSGGIDFCIGTSASPSSDPLEPQLIKVEKKLKAG
VSFIQTQAVYELDELKRFAEFVRKMDEEVKILAGIVPVIGVKMAAYMNENVPGIFIPQRL
IDELAEAPKGTGVSKGIEISARMIRQLKEERICDGVHIMFIGREERVPEILEAAGLL
>A0A1F9A287|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium RBG_13_43_22|TrEMBL
MKIHEIIKNQGKSISFEFFPPKDLDGENRLVPVIKRLETLGPDFVSVTYGAGGSTGKNTV
SLVERIQEGTSLTPMPHLTCIGQSYGDLKTILDHYKHLGIENVLALRGDLPQGTSDADFP
EDCLTCAKDLVDLTATYQAFSIGVACYPEGHIEAPSLEKDLLFTKRKIDSGAHFAITQMF
FENRFYYDFLNRAEKIGIHIPIIPGIMPILDIKRTGEFCRRCGTTIPNSLVARMEKASPE
DAGLIGREFAIEQCADLIRQGVRCFHFYTMNQAETVIDILGSLSLGRQ
>A0A0D7AYY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cylindrobasidium torrendii FP15055 ss-10|TrEMBL
MKVIDKIASRDASRPFYFFEFFPPRTDQGFENLLSRIARLAFLKPLALSVTWGAGGSTKE
RSLDLAGITQKEHKVDTILHLTCTNMLQGMVDDALMTAKQRGIQNLLALRGDPPKGKEEW
LPIDAQFQYGVHLVKYIRDHPDFGNYFCIGVAGYPEGHPDTDNDEDAEIEFLKAKVDAGA
DYIITQLFYDVDKFLTWHAKVRAKGITVPIIPGVMPIQTFASFQRLIKLTGTSVPEQVMH
DLEAIKHDDQLVKDFGVNLAVDMVQRLTAEGINGIHFCTLNLEKSVQRVLEKLGWTGAQN
SPTLLKNKLIEDTVSNDLSVAAKTATTDAAASLASISKTDGEAGAGELNNAASWDDFPNG
RFGDFKSPAYGNRDPWGNLTHIAPSHLGSPKTIGDLTNIFLDYLHSKRQTTPFSPEPLSA
ESATILPHIEKLTKRGWWTVGSQPAVDGASSSDPVFGWGPRSGFVFQKGFVEFFCDEEDV
DGIARRIHERGRGWVHWIAANARGDIRGHAASDDRNAVTWGVFPGQEIIQTTIIEKESFL
SWKDEAYSIWAEWASHYRPGTEERELLDQIRKNRWLVSVVHHDYKDTDALWMLFD
>A0A7Z7LI44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ciceribacter naphthalenivorans|TrEMBL
MAIKHDRNVPTAQRLRYSFEFFPPKSEDMADQLWKTVDELCLWDPDFVSVTYGAGGTTRE
PTLSTVRRLIAETPLRTASHLTCVGATKEEVHQVVEQFRAVGVNHFVALRGDPQDGMGTA
YQPHPGGYANAAELVAGLRELGDFEISVSAYPEKHPESPDEAADIDMLKRKVDNGACRAL
TQFFFDNDVFERYLERVRAAGISIPIVPGIMPIQNLNQLKRFASMCGATIPAFLDKRFAG
LDEQPQARAEVAAEVAAEQIADLSSRGIADFHLYTMNRSALVNATLRNLGLEPKGRRSEG
TGAAA
>A0A1Q9S4D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. CNS-004|TrEMBL
MPGVTDLAGALRRASYEVLPFTGTEAAVVAHVPTDVPLTVSTSHARGPEPTVDLAVRLTG
HGYSVAPHLAARQIRGTTHLSDLVARLRDAGVDSAFVIGGDAPEPAGPFADAFALLVALD
DLGHPFQRIGVAGYPEGHAGIATDLLDEALEKKAPYATHVITQICFDAGATVGWARQVRE
RGVDLPVRVGLPGVVSRQKLVRISAGLGLGQSARFLLKQQSMFWRFFLPGGYHPGRLVGR
LAPHLHGPATHLDGFHFFTFNEVESTEAWRRSVLARLT
>A0A1G9W9S1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas pantelleriensis|TrEMBL
MSVQEHPLGISFEFFPPNTEAGHEKLVGVRDALAERGPRFFSVTYGAGGSTQARTRRTVS
MIGESGINTAPHLSCIGSDKGELRELLAQYREEGINSLVALRGDQPSGMGGIGELRYANE
LVEFIRAETGDHFEIAVAAYPECHPQAPSFEHDLQNFVRKMKAGANLAITQYFFSAEAYF
HFADRARALGVEAPIVPGIMPITNYTKLARFSDACGADIPRWMRKQLEAYGDDSESIQAF
GEEVISRLCQRLLDGGAPGLHFYTLNQATASLRVLDNLA
>A0A316C2E2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudaminobacter salicylatoxidans|TrEMBL
MKNFGFSRRSGIGGKISVSFEFFPPKSEEMEARLWDTVTRLEPLQPEFVSVTYGAGGSTR
ERTARTVRRILTETSLLPAAHLTCVDATCGEVDKVISEFTDMGVTRFVALRGDPVEGVGA
CYQPHPGGYANGAELVGALKKAGNFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGVLPVHNFAQVANFSARAGAHVPAWLAERFD
GLQNDPQTHALVAAAVAAEQVLDLIERGVDDFHFYTMNRADLSVAICHMIGIRAQAGAGA
AIAVPSSAAA
>A0A0T5VTR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter ginsenosidimutans|TrEMBL
MKITDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QANGLLQKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHCYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMNTDFKYLKKKVEAGAEFIVTQMFFDNQKYFDFVKKCRENDINIPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNNEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKKIAKAIF
>A0A1I6KE39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. cf046|TrEMBL
MTNAPTATNLMTDFSLEMTGKDIDDLDQAAGLIPAGTRVNVTFLGNEDLEMRLAASRSVL
AKGLVPVPHISARRLTSRAELETYLGALRDAGAIDSVFAVGGDPSEPAGPYSDSESVIRS
GLLAEYGVRRVSIAGYPEGHPDIADDVLWDALAGKADSLAKQGLEGTIITQFAFDEEPVF
AWIEKVRDRGITLPIRIGVPGPAGVKRLVGFARRFGIGANAMIVKKYGFSLTNLMGTAGP
DKLICALESGYDAERHGEVHLHFYTFGGLTATSEWIQRFGQN
>A0A2T5FXR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas oleivorans|TrEMBL
MMTFSVAQLEEARCALDAPLYADLAGDAEVSFEFFPPRTEKMEETLWSAIQTLAPLGPRF
VSVTYGAGGSTRERTHATVERIARETDIPPAAHLTCVDASKAEIEEIARAYWDAGVKHIV
ALRGDPPVEGTKFTPHPEGYQGAADLVAGLRKIAPFEISVAAYPEGHPEAVSPEADIDNL
KRKLDAGATRAITQFFFSPEAYFRFRDRAAAAGISAPIVPGILPVSNVAQTRKFAAMCGA
AIPDWMDRLFEGLDDHPAARQLVAATVAAELCRRLYAGGVRQFHFYTLNRAELSFAICHL
LGKRVKKAGALEKAA
>A0A4R0PAS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oricola cellulosilytica|TrEMBL
MRSAFKSVNDATKDDTGIRVSFEFFPPKTPRMEETLSEAIEKLAPLKPDFVSVTYGAGGS
TREPTRKTLQKVIGTDATPAAAHLTCVDATREDVDAVAADFMSLGITRFVALRGDPADGV
GAAYRPHPGGYRNAAHLVEGLSAMGALDISVAAYPEKHPESPDFATDIDMLKRKVDAGAA
RAITQFFFDNDTYERYLERVRGAAIDVPVVPGIIPIHSFKAVRNFASRCGAEIPAWLAER
FEGLDDDPQTHALVASAVAAEQVFDLVERGVTDFHFYTMNRPDLVFAMCRLIGIRADTGD
DGELHAA
>A0A349Y0G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium sp|TrEMBL
MRSETARRDGDIRLSFEFFPPKNAEMETQLWETV
>A0A8I0SBY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas mendocina|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMDVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRSETGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVRKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDAESIRAFG
EQVITEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLDLKR
>A0A7Y8SMH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonadaceae bacterium|TrEMBL
MESQKQFKSRFSFEFFPPKTDKGWEKLQTVRDQLAGVNPDFFSVTFGAGGSTRDRTIETV
LHLHKKGISTAPHLSCVGGTREEIRELLDVYKKNGINRIVALRGDMPSGMGASGELRYAN
ELVEFIRQHSGDHFNLEVAAYPEFHPQARSAEDDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSESIRQ
FGEEVVTRMCEKLLAAGAPGLHFYTLNQAQPSLSIWENLGISEREKISF
>A0A2K9KIQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus siamensis|TrEMBL
MGLLQDLEERILIGDGAMGTLLYSYGIDRCFEELNVSKPDEIKRIHKAYVEAGADIIQTN
TYGANFIKLSRYGLEDETKKINQEAVKIARASSDSAYVLGTMGGIRTFNKNAYSLEEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETELPIMLNVSMHEQGVLQDGTP
LREALSSIADLGADITGINCRLGPYHMIEALTEVPIFRDAYLSVYPNSSLPSLEEGRLVY
DTDDAYFRESAVQFRTQGARIIGGCCGTTPNHIRAMAEAVRGLSPVTDKEVKIRREEEVI
SVRDERTEPGLNEIAAQKRSIIVELDPPKKLNFDKFLQAAAELKETGIEALTLADNSLAT
PRISNAACGSLLKERLDIRSLVHITCRDRNIIGLQSHLMGLDTLGLTDILAITGDPSKIG
DFPGATSVYDLTSFDLIRLIKQFNEGISLSGKPLGKKTNFSVAGAFNPNVRHLDKAVKRL
EKKIECGADYFVSQPVYSEQQLIDIHHETKHLNTPVYIGIMPLTSSRNAEFIHHEIPGIK
LSDSIREKMALAGEDKRKQKAEGLAIAKSLLDTACELFNGIYLITPFLRSDLTSELAAYI
KQKDEKRADVYLH
>A0A438D035|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vitis vinifera|TrEMBL
MLMGDLCQLAKDMAQNLLASDLFNELDPEIPSEVTAALEPIKDNDEAVKAYGIHLGTEMC
KKILAHGIKTVHLYTLNMEKSALAILMNLGLIEESKISRPFPWRRPTNVFRVKEDVRPIF
WANRPRSYISRTIGWDQYPHGRWSDSCNPSYGGLTDYQVIVGKVGKGHGVGSLENY
>A0A094FPP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudogymnoascus sp. VKM F-4517|TrEMBL
MKTTWKDIQPVPTSQEFLDIVLSRTQRRLPTQIRAGFQISRIRNFYTRKVKFTQETFSEK
ISLILDGFPRLQDIHPFHKDLLNTLYDADHFRIALGQLATAKHLIETVSRDYVRLLKYAQ
SLFQCKQLKRAALGRMATICKRLKDPLLYLDQVRQHLGRLPSIDPNTRTLLICGYPNVGK
SSFLRSVTRADVDVQPYAFTTKSLFVGHFDYKYLRFQAIDTPGILDHPLEEMNTIEMQSI
TAIAHLRSAILYFMDLSEQCGYTVAAQIALFQSIKPLFANKLVFIVINKIDVMRPEDLDP
ESQAQLQALLKPGDVEMLQLSCTTEEGVQEVKNAACERLIADRVAQKLKAGTNSNGAVGG
RLGDVLARIHVARPMNGVVREAFIPDAVKEMKKYDKTDPERRKLARDIEEENGGAGVFNI
NLKDKYMLENDEWKYDKVPEVLDGKNVYDFIDPEIEAKLAALEDEEEKLEAEGYYDSEDD
LEDAEDADIRMKAELIREKRILIRNAAKMKKSLKNRAIIPRTLTKAKLTDMEDHLDSLGL
DTTSLTTRARSQSRGRSVVRSRTGTEDVMDVDSPEYEAKMRAKSRARSQSNRREDGVPEG
TARTKAERIAKLGQRHRNRMARAGEADRHVAAAMPKHLFSGKRGVGAAKLQLHRGVFQLE
KLNLGSSHTHTHTLHDAYQGHAKPGGAGEEAYFLVRVLPAKDCPGVAQSVYGLETCMHLT
CTDMGKEKVDDALKNAYKAGCTNILALRGDPPREKEKWVATDEGFQYARDLVRYIRKTYG
THFDIGVAGYPEGCDDQTDADLLLDHLKEKVDEGATFIVTQMFYDVPNFLDWVSKVRAKG
ITIPIIPGIMPISTYASFLRRCNHMNARIPPGWIEAMEPVKNDDAAVREIGRGLVTGMCR
AILESGINHLHFYTMNLAQATRGVLEQLEMLPSEERPLKQALPWRQSLGLGRRGEDVRPI
FWRNRNKSYVMRTQEWDEFPNGRWGDSRSPAFGELDAYGIGLKGSNEQNIKLWGQPKSVK
DIANVFLRYLNADVDSLPWSEAPISNEADVIKNQLVKLNERGLLTINSQPAVDGVKSSHP
VYGWGPLNGYVYQKAYLELLVAPELIDELLDRIAKDPEVTYYAVTNTGTLRTNAPSDAPN
AVTWGVFPGKEIVQPTIVETISFLAWKDEAFRLGMDWAHCHETSSPSRNVIQRVMETYYL
VNIVHNDFHQRDGLFSLFEGLSVPNIDEPAEGDVAPAAAAPATNGDKVEDAPPAIVSNVL
PVA
>A0A837WX79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. Hex_13|TrEMBL
METQKQFKRRFSFEFFPPKTDKGWEKLQGVRNTLAEVDPDFFSVTFGAGGSTRDRTVQTV
LDLHKRGVSTAPHLSCVGATRDSIAELLDVYRDNGINRIVALRGDMPSGMGAAGELRYAN
ELVSFIREYSGDTFNIEVAAYPEFHPQARTAEDDLKNFARKVEAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLTRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCAKLLAAGAPGLHFYTLNQAEPSQSIWKNLGIGEREKIAF
>A0A101VCN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfitibacter sp. BRH_c19|TrEMBL
MENRFKESLLDKNTVSITWEVVPGRGAREKAQEVAMEAAEIAAKSGKIHAITITDMPGGN
PAILADTLGMEMLELGIEPLVHFTCKDKNRNQMESQLYSLDRAGVRNLLVMTGDYPVSGF
KGRPKPVFDLDPIHTVKLISDMNKGLEVQGFKGMLQHAKSDFFSGVAVSPFKATEAEQMA
QYFKLKKKIAAGGNFVVTNLGYDARKFHEVIQFMKLNNLNVPIIGNLYVLPYGAARIMNQ
NQLPGCVVTDKLLAQLDEERKAPDKGVGARLLRAAKMYAFMKGMGFDGIHLGGHNLKFEH
VEYIMEKGEELSANWQDYISEFDFPMPDGFYYYEKDPNTGLNTENPTSTKDRPLDAPVGG
VYRLSRVVHSLMFEPNKKFFGMMRGVSKSVEGSSMEKLYHGLEHLAKVIMYDCKDCGDCA
LSDLAYVCPMSQCPKNQRNGACGGSFNGWCEVHPNKKKCIYVKAYSRLKNYGEHSQLDDY
HVDPCNWDLHQTSSWINFYLGKDHSSDRLGIKKPEK
>A0A373B214|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. SWAC57|TrEMBL
MSLLAQYFAQQQFCVLVEYLSVQQAQSPVKTQFAGFPAAMTLADRVHADDDEAPLMVAKQ
YPQAIEKVIHFSGKARDIRDFEQFLQDAKIQGQKNLLLLTGDKLKQHHYSHDLEPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMAAL
QDAHAFLAQHQYAQKILACVMPLTLARAKFMLNHKVAGIVITPHILKVLQQEKEQGLSDR
VYVRCALQILMCRHLGFAGVHLSACHQPEEQMLLERYIEEYRHLSFAECERLWNTLWQVQ
TGTEFHPKLTYYSRPATSSQIIKYQHLHLMHDALFESKLAKGVGRFIFNFNVWDRTKANN
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTAILKEKLIPTVSIAVRGTSSWKNWYVESAN
>A5ATB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vitis vinifera|TrEMBL
MKVIEKIRDAATEEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGST
ADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHGQD
KFVQIQGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDVILNGVATSEAYQSDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPSEVTAALEPIKDNDEAVKAYGIHLGTEMCKKILAHGIKTVHLYTLNMEKSALAILMNL
GLIEESKISRPFPWRRPTNVFRVKEDVRPIFWANRPRSYISRTIGWDQYPHGRWSDSCNP
SYGGLTDYQFMRPRARDKKLQDEWVVPLKSIEDVQERFIKFCLGKLKSSPWSELDGLQPE
SKIINELLGNINSKGFLTINSQPAVNGEKSDSLSVGWGGPGGYVYQKAYLEFFCSREKLN
ALVDKCKGHPSLTYMAVNKEGTWMSNVGPGEVNAVTWGVFPAREIIQPTVVDPSSFMVWK
DEAFEIWSRGWALLYPEDDPSRKLLEEVQNSHFLVSLVDNDYINGDLFAIFMEF
>A0A073CCQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planktothrix agardhii NIVA-CYA 126/8|TrEMBL
MNRFRTACQTLDEFIVTAEVAPPKGADPSQMIEMVRLLKGRVHAVNITDGSRAVLGMSSL
AASIILIHHGVEPIYQLACRDRNRIGLQADLLGAQALGIRNVLALTGDPVKAGDHPDAKA
VFDLESVRLLQAIDKLNQGKDWNNKTLPDGATDLFPGAAVDPQSSSWSGLKSRFERKIEA
GAQFFQSQLITDFDRFDQFMTEIADSSKKPILAGIFLLKSAKNARFINKYVPGVCIPDSI
IDRLEQAKHPLEEGILIASEQVKIARELCHGVHIMAVKREDLIPKILDLSGIKPLF
>A0A196QV78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter geojensis|TrEMBL
MTSPRVSFEVFPPRNVDAGFNLWDTAQMLAPLEPRFFSVTYGAGGTTRDLTHDAAHVLRR
TSGLPVAAHLTCVGASKAETLEVADTFAKIGVTDIVALRGDPQDGAKTFTPHPEGFADSC
ALIEALADKGTFNIRVGAYPDSHPEAADMDANVQWLKRKFEAGADEAITQFFFETDSFLR
FRDACAKAGIDKPITPGILPVLNWKSARNFAKRCGTPVPAWLDDAFEAAIRDDRHDLLAT
ALCTEMCSTLVEEGVEDLHFYTLNRAELTRNVCRALGVTPQVSVRDVA
>A0A2W7NIN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Breznakibacter xylanolyticus|TrEMBL
MLREKILQRKNGLLFYGLTPPKLHTESERLSAIAQKQMERLSGIAIDGLILYDIQDETAR
IDTPRPFPYMPTLPPETYSEQYLGALDVPKIIYKSVGKYSPEEFRQWLMNHEANIDCTVF
VGSPSQSHQPALPLSEAYRIRQQLRSSMVLGGVAIPERHVTKQDEHQRMFDKIDNGCSFF
VTQCVYNLDNAKNVLSEYYYACRDKQQLPVPVVFTLTPCGSLKTLDFMKWLGIEIPVWLN
NELKHSEDILKNSIDACRKIAIELMEFSAPKGIPIGFNIESVAVRKDEIEASIELLKDLR
RLM
>A0A3S4WZF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromonas encheleia|TrEMBL
MGFHSARQVEALNQSLADLGGDISVSFEFFPPNSEGMENTLWQSIERLQVLEPKFVSVTY
GANSGTRDRTHKVIKDIKERTGLIAAPHLTCIDASRDELKTIARDYWNSGIRHIVALRGD
LPPGIDKPDMYATDLVALLKSEADFDISVAAYPEGHPEARSAQSDLLSLKRKIDAGADRA
ITQFFFDVETYLRFRDRCAAIGIDTEIVPGILPVSNFQTLTKFAGFTNVKIPGWMHQRFE
GLENDQMTRNMVGASIAIDQVRVLSQEGVKDFHFYTLNRSELTYAICHTLGVRPKGQA
>A0A4R6V5N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora succinea|TrEMBL
MATVTERIQRGVPTFSAEFFPPKDDEGEATLWRTIRDLEPLDPAFVSVTYGAGGSSRDRT
VRTTGRIATDTTLTAMAHLTAVDASLDDLRQVIGSYAAAGISNVLAIRGDPPGDKDADWV
PHPAGLSYTEELVHMVRRLGDFCCGVAAFPYLHPRSVDEDSDTRFFIQKVKAGAEFAITQ
MFYDADQFLRMRDRIAAAGCDIPIMPGLMPVTTPKSAERGADFAGAPLPSVMSERLDPLK
DDKAGYRDAGIDLCVELSQRMFDEGVTNIHYISMNRSPAVVDVVERLGIAARPSV
>A0A1F1G643|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia sp. HMSC069C04|TrEMBL
MATVHPALSFELFPPRSQASCESLLRTIAELEGTNPDYVSVTYAGDAKRRQKTLALLDHL
VHETSLTPLAHLICAGHSVHELERAVRLILGLGVRGFLALRGDIQEGQVSELPFARYLVE
LIRRVEREDFAHLAAGKVSIGVAAYPQKHPESASLLQDIEILLSKQRAGADFAITQVFFE
DERYSALVDSAHLAGVDIPIIPGIMPVTSLKRLQNLCQMAGMEVPTDLAYALETATSSAE
LHRIGVEYALNQCRAVMDAGAPGLHFFTFNEHAAVLDVLDQLDLPRYSNRFSQSLSELEY
V
>A0A6I6WJD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. NHF165|TrEMBL
MAIGISAPRTDRPPAVRELLASGKQSFSFEFFAPKTEKGERTLWDALRRIEAVSPTFVSV
TYGAGGSSREGTVRNTERIATETTLTPVAHLTAVNHSRTELRNVIGQYADAGIRNVLAVR
GDPPGDPLGEWVPHPQGLRYASELVELIKESGDFCVGVAAFPEMHPRSSDWETDVRHFVN
KCRAGADYAITQMFFRTEDYLRLRDKAAAAGCETPIIPEIMPVTNVGQIERFAQLSNATI
PPELIDRLRAVEDDPKAVRSVGIEYATEMCTRLMAEGVPGLHFITLNHSTATLEIHQNLG
LHPRP
>A0A1X2G5B6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hesseltinella vesiculosa|TrEMBL
MKFIDKIRQAEVEDRPYWSFEYFPPKTPQGVQNLYNRIERMKEFNPQGISVTWGAGGTTS
DLTAEIVKTSQVKYGVETMMHLTCTNMPKEKVDKALEAAKACGCQNILALRGDPPHGQDR
WESCEGGFSHAEDLVKYIRNKYGDYFGIAVAGHPEGHMDASSKEDDLLHLKAKVDAGADL
IVTQLFYDIDVFLDFVQKCRAIGITCPILPGVFPIQNYQGLKRVISFNDNFVPEKIWQDL
EPIKEDDAAVKEYGIQLAIDFIEKMQAAGVKGVHFYTFNLDRSTRLILERLNWIQPAQTP
AQSVVSQTAIADPTSN
>A0A2G2Q0M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobium sp|TrEMBL
MTTLSFEFFPTQTEEGTSRVLAVRDELAAFNPEFFSVTYGAGGSTRGRTFSMVEAIQQRG
IAAAPHLSCVGDSTADLRDLLQRYQALGINRIVTLRGDLPSGSGLASSELRYANELVEFI
RKETGDHFTLEVAAYPEMHPQASSFEKDLENFVRKVKAGADSAITQYFFNADSYFHFVDR
VRAMGVDIPIIPGIMPITNYSKLARFSDSCGAEIPRWIRKQLEAYGDDSDSIVKFGEEVV
TDMCRRLLDGGAPGLHFYTLNQAKPSLAVWKNLI
>A0A315CXV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. Hippo3|TrEMBL
MSGLKLPISLEFFPPKTPEGAEKLRGVREKLYALKPEFCSVTYGAGGSTQEGTFATVAAI
QAEGVAAASHFSCIGATKASVREELATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLV
AFIRAETGDDFHIEVAAYPEIHPQAKSPEADLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGVDVPIVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQAYGDDVESIKAFGL
DVVSDLCEQLINGGVPAIHFYTMNQSAATTEIWRRL
>A0A2T1HTY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alsobacter soli|TrEMBL
MSRSPVRVSRRCGKRPIRVSFEFFPPKTDEAEEALWDSIHRLAPLGPDFVSVTYGAGGST
RERTQSTVTRLVRETALQPAAHLTCVGASRDEVDAVVRDYAAAGVNHIVALRGDPPGGVG
AAYAPHPQGYQSTADLVRGIRDVAPFDVFVSAYPEKHPESPSLDHDLDVLQAKVDAGATR
AITQFFFDNDVYFRFLDKVRARGIDIPIVPGVVPVQNFKQTAGFAARCGASVPNWLAERF
EGLENDPATRRLIAAAVAAEQVIDLLDRGVRDFHFYTMNRADLVYAICHLLGMRPQAAEE
GAEAGEDASASLPLAANG
>G8AV62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum baldaniorum|TrEMBL
MTAPLSAPPSISFEFFPPKTESMEQGLWQSIRRLAPLAPSFVSVTHGAGGSTRERTHATV
CRIQDETGLPAAAHVTCVGATRDEIDTIAHSYWNAGIRHLVALRGDPSDMPGGSGRCEPS
PGGYAYAADLVAGMRRIADFEISVAAYPESHPEAPSVQFDLDNLKRKVDAGATRAITQFV
FDNDVYFRFLDRCAAAGIHVPVIPGILPITNVARAVEFAAKCGASMPARLVETFEGLDDD
PETRRLVAATVAAEQCQALQAQGVRDFHFHTLNRSDITLATCHMLGIRAAVPAP
>A0A1E3KBC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryptococcus amylolentus CBS 6273|TrEMBL
MPPLTSLIAAHDGPFHNYEFFPPRTDAGLVNLLERIRRLTSAPLQRPLAVSITWGAGGST
AEKSLELAEQVVKMGVEVVLHLTCTNMAKEKVDLALQKCKALGIQNILALRGDPPRSEEY
AVTPNVPDFFQHADDLVRYIRAEHGAYFCIGVAGYPTAHPDSETDEDEMKWLKVKCDAGA
DFIVTQLFYDVDGFLAWVKECRAQGIKQTIIPGIMPIQSFGSFRRLVNLTKCPVPSSITS
DLQPISSDDAAVKQYGATLATKMVKQILDSGEIHGVHFCTLNLEKSVRTILDNLNWVERD
QRDSVSSLDRNRFIESDEDARPSGIPINGKTRSYSNSASLSISPSDASHLAQLGLTSALP
PKSQAHSTATGAPSGAGATGEDSWDEFPNGRFTDVRSPAYGEIDGWGSGLKITAAQALKE
WGVPTTSSDLSTLFTSYLQNSPATPTTPFCDLPLSPESQTILPHLLKLNSADKCFWTVGS
QPAVDAAKSEDSVVGWGPRGGYVFQKAFVEFFVRPEEVEGLVRKVDELGKSMITLYASNK
KGDFKTNTDSSAVNAVTWGVFPGQEIVQSTIIEQESFLAWKEEAFDIWTEWAELYPRQSA
ARKLLEGVSGEWWLVSLIHHDYKKEDALWKFLLDV
>A0A430V760|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus scotoductus|TrEMBL
MKIRDLLKARKGPLFSFEFFPPKTPEGEEALFRTMEELKVFRPAFVSITYGAMGSTRDRS
VLWAKRILDLGLNALAHLTVAGQSQEEVAGVLDRFVEAGVENILALRGDPPQGERVFRPH
PQGFRYASELVAHIRTRYGEGLSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRVGIEIPILPGIMPITSYAQLRRFTEVCGASIPGPLLSQLERHQ
EDPKAILEIGVEHATKQVAELLEAGVEGVHFYTLNRSPATRRVLERLGFKPA
>A0A4R6FPN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stakelama pacifica|TrEMBL
MTISVDQLEEAQFALGAPLFADIDGDLEVSFEFFPPKTEKMEETLWESVRTLEPLGPRFV
SVTYGAGGSTRARTHQTVERIQRETSMNAAAHLTCVEASRDEINQVAEEYWASGIRHIVA
LRGDPPEAGQKFAAHPDGYANAAELVAGLKKLHPFEISVAAYPECHPDSSNVQADLDNLK
RKLDAGASRAITQFFFTPEAFFKFRDAAADHGIDAEIVPGILPISNVAQTRKFAGICGAD
IPKWMDRLFEGLDDHPGARQLVAATIAAEMCRKLYAGGVRHFHFYTLNRAELAFAICHLL
GMRAKDRAGEKAA
>A0A2U3P5W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium numidiamassiliense|TrEMBL
MSTESGCPKRMQFGPCGGVRPGGQCEMRPGACAFGDVVPWSGVQLPPRPAHAPLVLADFS
CTPFDRDDVAATAAVLAPGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVAPWITLSCRDRN
RVVLEQELRGLRSIGVDTVLCVTGDGRGYDVRPDVTQTFDLDGPRLVSLAASVGMIPAVP
ETPTAPPTRARPARLVEKQRAGASLAVLNHVPTPDMIAAFMKSARASGLSIPVIAAVAVF
TDNVSAAVLQGLPGLELDQAAVEQVLSAADPVAAGIAAAVSEARALLSIDGVEGVNVSGL
ASASGAHIGAEIKAEVGRRIRAEMS
>A0A291IDX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylomonas koyamae|TrEMBL
MNISFEIVPRTLDAFEKQYAFVQSLNDCINIINVPDIQRFDMRSWELARHVDRNQYQFIP
HFRAIDFKIESGELYRIIEDYQLDSVLLVTGDPPEGLKRSYCNTDVVDLIRAVRRRFPKL
NIYAGFDPHRQGLQHECHYIQRKADAGANGFFSQPFYDHRLVELFAEHMDGLETYIGISP
VVTSASQNYWEVKNHVKFPKHFRPDYDWNVEFANRLIGSAAENGWHVYFMPIKVELKKYF
ERIKLANPRPTTLSVTG
>A0A1W9SVC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4572_130|TrEMBL
MNLKESLEKKRFVVTSEVQVPLGDEEPEVLVKSLSRVKGRVDGVSVSEMELEGVVSDTIK
TCDLLKQNNLNAIYQTTTRDKNRYQLQKDLTLAHETGVENLLVFTEDYRISGDTLQESMF
FHVDSGKLGSVLDHLKQGVTLEGKELDKKVEFILGSGVETPWGKNMPKRGMEEMEDMMNV
GAGYFLTTPIFDVDQFARFMKQVQPFKIPVIAEVMILRTAGMGKFLNRHFKSGLVPEWVI
QKLMKAPNKEKASMELFADTVNNLKDICQGVHIITIGGVDNLVQYLNAAKLR
>A0A0U0J6L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus pneumoniae|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPYFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRVA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQATHALFNHQSLG
>A0A5K0WA67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nymphaea colorata|TrEMBL
VDAGSDLIITQLFYDTDIFLKFVNDCREIGITCPIVPGIMPINNYKGFLRMTGFCKTK
>A0A4Q0T5X9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Granulicella sibirica|TrEMBL
MAGTSVVEGAGVAQAVDRLFAAVAGEDGAERKTVLCDGAMGTMLYSRGVFINRSYDELNL
SQPELVRAVHAEYLQAGAQIIETNTFGANAFRLERYGLKDKVRAVNIAGMRLARQCVNEI
REKQASEAFVAGALGPLGVGLAPRGIVAVDEARDAFREQVKALAEGGPGVGADLFVIETM
MSVAEVEQAIGAVKDEAPGLKIIVMVTVDEDGNCLDGTSAEDAVKLMESWGADAVGCNCS
SGPQTVLAVIERMRAVTRLPLAAMPNAGIPRDVDGRQIYMTSPEFMGGFAKRAVKAGATF
LGGCCGTTPAHIRAMRHSLRALGAMEAGIHAVVEAPVESKVEPPPLKDRSKIGGMIAASE
FVTLVEIVPPKGIDCSKELEGARQLYLLGVDAINVPDSPRASARMSAQSLCVQIQQHVGI
ETILHYTCRDRNVLSIQSDLIGASSIGLKNVLCLTGDPPKMGNYPDATAVFDVDAIGLVK
IVQGLNHGMDIGKNPIGGSTGFTVSVAANPGVPDLDYEVRRFASKVEAGAEFCITQPVFD
MRVLEDFLRRIEGFRIPVIAGIWPLTSLKNAEFMKNDLKVRVPDEVMARMASAGSVEGAR
AEGIKIAREMLAEAKTLGHMMVRGVQVSAPFGKYKAAADVLGLGEKE
>W0EAP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfitobacterium metallireducens DSM 15288|TrEMBL
MTFNNLREHLQQHVVIGDGAMATLLYQFGVPVGSCYEELNLTHPALIRSVHEAYIRAGAQ
LIETNTFRVNREVLTRFGLEQKVGEINRTAVKVAQEAVAVAEKNAFIIGSMGSILAGRVR
TEPLVSYRSLYEEQASALLESGVDGIMLETFEDLEELLLVLELMLSLTDRPILAHLATPQ
VGRTRDGYTVTRSFELMRKAGADVIGLNCRLGPTEMLRTLEQTQVPEGALLSIFPNAGRS
GFVEGKLSFKSSPEYFADYALRLRDEGVRLIGGCCGTTPDHIRAIAQALQELSPIQRVNP
DLKENNQDKEKDQVRFHIQPQAHVKAYTKDQRTIIERAQEEHTVIVEFDSPKGLNTEDFF
NGCQALDSAGAAAITLADNSLANVRMSNLALGALLKERYDIEPLLHVACRDRNLIGQQSH
LMGLHALGIHQILVITGDPSRYGDLPGASSVFDSNSFELIRMTKQLNEGLSFSGQAMNHS
AQFIVGTAFNPYVRNFETAIQRLERKIEAGADFVMTQPVYDGETLQKIYEGTKHLPIPVF
VGIMPLTSQRNAEFLHNEVPGISLTEEALQRMSGLKGEKARQEGIAMSKELLDQAVKVFN
GIYLITPFNYYKMTAELTEYVLNICGNSNGEKVEFYDSACPNKNRSF
>A0A2J9KSV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mobiluncus mulieris|TrEMBL
MASGVDWVAPDAGGVLDTPGAPVAFTSVSRGANPKSSRNPTRPVRVSFELYPPRNPDPFS
QAWAGIDRLLDAHPDYVSVTFGTSNSTSASSQSVLAHALQRLGRPVLAHLTCVGKTRTEL
STTITEMLDIGVRDFLALRGDNPKGSVNWEPAPGEFSRASQLVTLLREVAAEYLGDARAI
SIAVAAYPAGTVSARTNAVAALAEKQSAGADFAITQVFYNADDYGALLDSATYQGVSIPI
IPGIIPFTDAARLQRLEGLTGVSVPSRLQAISEISDPEERFLEGLSATLDFVNDLIQAGA
PGLHFYTFNRPRPVLDLVEHLRSRGFTHVDEDSSSELLDLMNAAMQRFSP
>A0A817SVP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MASYEEDLRYLKEKVDYGADFIITRLFFQPATFIKFESDCRSIGIQCRIIPGIFPIQAYA
SLKNIVRLAKLDVPEEILACIEPIKYNGEAIRNFGVQKCVDLCRTLLDSGKIHGLHFYTL
NREYATIEILRKLDRCVRPKSYFHRTSNCEEFPNGRWGLSFAPSFGALTDYHLFYIKIDA
TRDALLDEWGHELADKQDVRRMFACYIADEKNGRVKIVHHFPWKDEDISPETNFIHDHLI
KYNRKGILTISSQPAVNGKSSTDSIFGRGIKKWLCLSKSLFRIFTSEKKIPALRAVLKKF
PGVNYHFVNKSGEVNETSTEGEQPIALIWGVFAGREIIQPTVVGPISFMIWKAIDLSARL
INDYFSIL
>A0A7Y9DUT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetospora corticicola|TrEMBL
MATVMERIQRGTPTFSVEFFPPKTDEAERTLWNTVRSIEPLDPAFVSVTYGAGGSSRDRT
VRTTGRIATDTTLTAMAHLTAVDASMDDLRHVIGSYAEAGISNVLAIRGDPPNDKDAEWV
PHPAGFSYTEELVHMVRRLGTFCVGVAAFPYLHPRSGDEDSDTRFFVQKVKAGAEFAITQ
MFYDADQFLRMRDRIAAAGCEIPIMPGLMPITTPKAMERGADFSGAALPSAMSERLEPLV
DDAAGFREAGIDLCVELSQRMFDEGVGNIHYISMNRHPAVVDVVQRLGLTPSV
>A0A2Y9FUH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Physeter macrocephalus|TrEMBL
MDRPKPNVLPAGHCCPSLGTRAWEAGSARFSVPPSISRSSAMVNEPRGHGGPSPRWEDGT
SGSESSKDSSRCSTPVPDPERHERLREKMKRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKRLGLKNILALRGDPTGDGWEEEEGGFSYAVDLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEADLKHLKEKVAAGADFIITQLFFEADTFFRFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQALSLCQELLASGSVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGW
GPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGDNITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDSCLWQVVEDTFELLNRPPQGKRETEAP
>A0A829CZJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans str. 2002000626|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESV
>A0A817VRU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rotaria socialis|TrEMBL
MEFTLGDNQTVPGDCKMHAHETHLESIHNLNRLKRIESEGANIAGKICSLQSAKYVSLTE
KISKRIADNDRWFSLEFFPPRTPSGAANLIGCFDRMAAGRPLFCDITWHPAGDPAGDKET
SSMMIANTMLNYCGIDTMLHITCYGAKKAAMLEYLYKAKDCGIRSLLALRGDPHVGEEWN
PAKSDFRYALDLVKFIRQHFGDYFVICVAGYPQGHPDSTSYEDDLDYLKEKIDCGADFII
TQLFFQAETFIKFESDCRSIGIKCPIIPGILPIQGYASLRNIVRLAKLDVPKEILACIEP
IKDNDEAIRNFGVQACLDLCCALLDSGKVNGLHFYTLNREFATIEILKRLGLWLDEQSLR
ALPWKKTSFSHARSQENVRPIFWSIRPKSYVHRTSNWNEFPNGRWGISSAPSFGVLTDYH
LFYMKIDATRDELLDEWGRELTCEQDVWKMFACYIGGEKNSIDKVVRRFPWTDEELSAET
TLIQKNLVEFNKRGILTINSQPAVNGKSSSDPVVGWGTPNGYVYQKAYLEFFTSAENIPA
LRSVLKTFPGVNYHFVNKSGEANETNTDDEQPIAVTWGVFAGKEIVQPTVVDPVSFMIWK
DEAFSLWTERWGKLYEPESRSHAIIEKIANTYFLVNLVDNDYPQGSCLWTILDSMFEYQK
LPKKNVES
>A0A259DT84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. 17-62-19|TrEMBL
MATPQIHPNWDKVPDGITDGFSLEMTAKDEASLRDAAPLIPAETPIAITFLPGEDVAARV
AATVAVRELGFEPMPHFSARRITSEDDFEGYLRAVVQKAGVERCFIVAGDPPEPVGPYFD
TSALIATGAFERSGIKAIGIGGHPEGHPNMSEAECWAVLEKKVADITARGMAPLIVTQFG
FDPDAFLAWLKELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVTN
LLGTAGPDKLVDAFAKGLTAEHGKVRLHFYPFGGLTKTLEWLHGYNKKHGIGA
>A0A5A7N5C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kordiimonadales bacterium JCM 17846|TrEMBL
MTHHQPWIKPLGQPLFTGDLSAVDVSFEFFPPKTEKMEERLWAAVKMLEPLAPRFVSVTY
GAGGSTRERTHKTVRRLLTDTNLKPAAHLTCVGATRDEIDAIIQDYKEAGVKHIVALRGD
APDPSTGYRATPGGYENAADLVAGIRKIGDFEISVAAYPECHPDSPNLAADLDNLKRKVD
AGATRAITQFFFEPDQYFRYLDHVRSYGIDVEITPGILPVTNFEQLKRFAASCGASVPRW
MADLFEGLDDHPQTRSLVAATVASELCRRLQAGGVNSFHFYTLNRDELTYATCHMLGIRP
ARTADLPKDINR
>A0A3R8RF33|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANY
VRNELHIPTIAHLPAAYMTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFQYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGVHLYTMNNAETARTIHQATHSLFKHYS
>A0A2S2F6C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus suis|TrEMBL
MIGQTPSLSFEIFPPKPEVGNEKIIQTLDEMQGLAPHFISVTCSNNNLNVEETTVKLANH
VRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALRGDIIEGLPPKEDFRYATD
LISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKVDAGCSTLVTQLFFDNEAFYN
FQEKCSLADIEVPIIAGIMPIINRNQALRLLKTCENIHLPRKFKAILEKYEHNPESLRAA
GLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQATHSLFKHYS
>A0A1V1RDT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coriobacteriaceae bacterium EMTCatB1|TrEMBL
MRARADPSPAGGAGPGRRSYAAPERPLEEAQARSAEREGAQTRRERAMSRLREALERGEF
VITGEIAPPRGSDVSAMRETMALVGPLCHALNITDNQGASLHMSSLGACLVALEMGFEPI
FQQTCRDRNRLALQSDLMAAWALGIENVLMVTGDDPRSGDHPQAKGVFDVDSTQLLRIAK
DMNEGRDMQGRPLAGGTGFYLGAAMFPEAEPWDAQLARTVGKIEAGARFFQTQAVFDLEK
LARAVDALHAHGAKVIAGVLFLRSPRVIDFVNEHLAGLRVPDHVARRIKSAPDPLEAAID
LAVEQVAAIREIADGVHVMPLGLDGRVPEVLERAGVL
>A0A260TLK6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus fascians|TrEMBL
MSEDSVRGRSSRGFVTRTPSIVDRLRTEPEARIPFSVEFSPPRDEAAEARLWRAVREFEQ
LQPAFVSMTYGAGGSTRDRTVRVTGQIAEETTLLPVAHLTAVSHSVAELRSMVGSYADRG
ITNILVLRGDPPGDPLGEWEKHPEGVEYAEELVRMVRELGDFHVGVASFPEGHHRADDLE
QDTRCLVGKLRAGAEYSITQMFFDVDDYLRLRDRVSAYDPEQGAKPIIPEIMPITSLRSV
RRMLELSGTTLPSHLDEKFTRAAGSGAEEDKAAVREVGIELATNIGERLIAEGAPGLHFI
TLNFARATREVLSNLGLAAARV
>A0A4P6XHC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metschnikowia aff. pulcherrima|TrEMBL
MATVIERIKALKPDEKFCLFEFFPPKTDTGFRNLLARLHRMMALNPLFFTVTWGAGGSTS
EKSLDLAATCQKELGVTTVLHLTCTNTNKEVIDNALAKAKEAGVRNILALRGDPPRTQEY
WTPNCDFKNAIDLVRYIKEQYGDYFCIGVAGYPEGHVDGANETQQNPRKDLPFLVEKVKA
GADFIITQLFFDVDKFVAYENLLQSVPELASVRLIPGLMPITTHKVFVRATKLSHALVPR
EISDRLEAPGNDDDMVKSIGIDVLTKLISEVNRKTEGRIKGYHFYTLNLEKAVAFIIERS
PLLNLVDHNQAVDHEDAIGSDSDSEEPVKVTTRKTRRSLTVEDAQLALISDAFSKDRKKI
IDISTGKGVLGKDATWDEFPNGRFGDSNSPAYGEIDGYGPNLKLHTPEQIIQTWGTPEKT
NDISKLFMEYLSGKINVLPWVDTEISSETALIQEELFELNQRGWFTLASQPAVNACPSTD
KILGWGPSNGYLFQKAFVEFFIPKKDWDEKLAPKLSQHIEEKTITFYKGDRSGNITSNLP
IGENHQNSKTAITWGVFPSKEVLQPTVIDYESFKAWNEEAFLLWVEWARCYKKDTEAYKL
LESIYKDHYLISMIYHDFTDEYGLWTSLLSD
>A0A6B2WIC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID13588|TrEMBL
MALGTASTRTDHAVTIRELLASGERSYSFEFAAPKTEKGERTLWNAIRRIEAVGPTFVSV
TYGAGGSSREGTVRATDRIVSDTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNILAVR
GDPPGDPLGEWVKHPQGLLYAADLVRLIKESGDFCVGVAAFTEMHPRSSDWESDTRNFVD
KCRAGADFAITQMFFDADDYFRLRDRVAAAGCTTPIIPEVMPVTNVRQIERFAQLGNAPF
PPELADRILAVKDDPAAVRAIGIEFTTEMCRRLMAEDIPGLHFITLNHSTASLEIYENLG
LHQRS
>A0A177LGJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium sp. FP211-J200|TrEMBL
MKITDHIKNANGKTLFSFEIVPPQKGVGIADLYKNIDPLMEFNPPFIDVTTSREEYIFLE
RGNGLMERKITRMRPGTLGICSAIQNKYNVDTVPHVLCGGFTKEETEYLLVDCMYLGINN
IVALRGDAMKGEKYFEQSKGGHKYASDLVKQIHDLGTGKYLHEEIVSDDNSSFCIGVAGY
PEKHIEAPSMNYDLQMLKKKVEAGADYIVTQMFFDNQKFFDFVKQAREIGIDVPIIPGIK
PIATKGHLQMLPQVFKIDLPENLISEVLKCKTNSDVREVGIEWAINQCKELLDFGIPVLH
FYSMGKSDNILKIGREVF
>A0A420J650|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Golovinomyces cichoracearum|TrEMBL
MFISDKLAEAERSGQPTFSFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGNIA
QLTVEMVSIAQSHYGLETCMHLTCTDMGKEKVDDALSGAYKSGCTNILALRGDPPRQMEK
WTRTEGGFLYAKDLVKYIREKYGNHFDIGVAGYPEGCDDQDDPELLLDHLKEKVDAGGTF
IVTQMFYDVENFLEWVSKVRAKGISVPIIPGIMPINTYASFIRRANHMGCKIPPKWATAI
ESVKNDDSAVRSIGTGLVAEMCRKILASGLIHHLHFYTMNLAQATRMVLEELNLTPSEGR
PLKTPLPWRQSLSPRRRDEDVRPIFWKNRNRSYVMRTQDWDEFPNGRWGDARSPAFGELD
AYGIGLKGSNEKNRKLWGEPQCIKDVANIFVKYLEATIESFPWSETPITSESGMIKNELI
DLNQRGLLTINSQPAINGVKSSDPVFGWGPPNGYVYQKAYLELLVPDYLIDEILERVSRD
TDLTYHAVNIDGNLKTNTPNDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEAYRLGLD
WAHCHSALSPSRQLIENMMKKWYLVNIVNNDFHKSYGIYKVFEGLRVKDLEKPYSASISY
DESIPRTNGHKPKDPLTNGHMSKDPLINGLGTNKPTANGHKISAA
>A0A7M7NWR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Strongylocentrotus purpuratus|TrEMBL
MAVVTRVDQNGVPLKQVQEESALGLQNLIQSLHQNGNLTPTSLSRSPSPEPVMPFMRLSE
KIANRIASKDRWFSLEFFPPRTASGAVNLVGRFDRMFHGGPLFCDITWHSAGNPGGRKET
SSMEIARTMLNYCGLDTMLHMCCVSQSAEVITRHLEWAKECGIRNILALRGDVPGHTDEW
EPTPGGFNYATDLVKHIRKVFGDDFVIAVAGYPSGHPDAVSYEDDLKCLKEKVDAGADFI
ITQLFFEAKTFLKFVRDCRAIGITVPIIPGVMPIQGYHSLRSLVKLSKLDVPQEIMDVIE
PIKENDAAIRNYGVHQAVTMCKELFESGEVFGIHIYTLNREVATIEILSSLGLWCGEPKR
PLPWKTTANLKRKQEDVRPIFWASRPKSYVYRTQEWDEFPNGRWGDSSSPAFGELKDYHL
FYLASKSNQKQLQTMWGEEITCVEDVSEIFTCYLSGEPNRYGNKVTRFPWNDDEVSSETM
RVSSQLVSMNKRGVLTINSQPNVNGEPSSDPVVGWGAPNGYVYQKAYLEFFCSRENVAAL
LHILQDYPLVNYHVVNAKGTETITNTDRLKPNAVTWGVFPGAEVKQPTVVDPISFMSWKD
EAFGLWLESWRTLYKEGSPSWHVIQFIHDTYFLVNLVDNDYVKGNVLFEIIERMLERCGN
SKGDCRVGDIEDECIATKRLKVSEEEMSLSND
>A0A7K9TTA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroceryle aenea|TrEMBL
IPRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNYCGLETILHMTCCNQTKD
DITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDICVAG
YPTGHPEAESYEADIRHLKEKVFAGADFIITQLFFRSETFLKFMKDCQAIGITCPIIPGI
FPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGVVH
GLHFYTLNREVATTEVLKRLGVWNEDPR
>A0A7W9AIF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium boeckii|TrEMBL
MNLTVNQLEDARRALDAPLFADLAGDAQVSFEFFPPKTAKMEETLWSAVQTLAPLGPRFV
SVTYGAGGSTRERTHATVARIARETPIAAAAHLTCVEASKDEIREIAEGYWEAGVRHIVA
LRGDPPVEGARFIPHPQGFASAADLVAGLKAIAPFEISVAAYPETHPEAQSGQADLDNLK
RKLDAGANRAISQFFFSPDAFFRFRDRAAAAGITDEIVPGILPVSNVAQTRKFAAMCGAA
IPPWMDRLFEGLDDHPAARQLVAATIAAELCGKLYAGGVRNLHFYTLNRAELSYAICHLL
GLRPQVAQKEEAA
>A0A7H5F4H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lewinella sp. W8|TrEMBL
MRVTEYFEKAKGDTLVSFEVLPPLKGGSMQAIFDALDPLMEFKPPFIDVTYHREEFIYKR
RASGYYEKTAIRKRPGTVGICAAIMHRYGVDAVPHLLCGGFTKQDTENALIDLAFLDVQN
VLALRGDARKFEGKFIPEPEGHHYASELVEQITDMNKGKYLDELVNGDEATKTNFCIGVA
GYPEKHFEAPNLEIDLRYVKKKIEAGADYIVTQMFFDNQKYFDYVDACRAAGINVPIVPG
LKPLTKLYQLTSIPRLFHVDLPEDLVKAVTKAKDAEGRRRAGIEWCIAQSKELKERGVPC
LHYYTMGDSSTIHQIASAVH
>A0A7L2MCC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhadina sibilatrix|TrEMBL
MVNESQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLREKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSADPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A2N2CCV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-2|TrEMBL
MMIKDYIKEQVLLMDGAMGTYFAELTEGHYTLSEPANISKPGLILDIHKAYIEAGAKLIR
TNTFAANPYTLYRSFDEVKKIIMAGIDIANEAVKGRDCYVAYSIGPIGEPYDIEDYEIES
TYRKLIDIGLLKNVKIILLETFSRIDQVNQLVEYIHEHGPNIQIMTNFTVNQHGYTKVGV
NKEKIIQQTRQQDLVATYGFNCGIGASHLLSLIKTLDFDPSKMVAVPNAGYPDQQLERMV
YQSNADYFADTMIKICEEGVRIVGGCCGTTPEHIRKIRERLNTFDFSEIKSISRMKRKSL
PLTPLHNAFREKLENNQFVVAVELDPPFKMDMSLIISSAHLLKEVGVDIITFADSPLGRT
RADALLVAAKIKQLTGMEVLPHVCLRDKNLIALRGGLVGAHLSDIRNILIVTGDPIPSDD
RDEVKSVFNMNAISFMQYVTEINSELDLDTFYIGGALNPYTQNMEVTLERVLKKKEAGAS
YLLTQPVYNDAGIEAIKKVREKTGMKILGGIMPLVSLRNARFLHYEFPGILIPDDVMAKF
KETMTKDEAEKVGVELAVALATKMKPHVDGLYFMTPFNRATMIEKIIKRLDVL
>A0A6I2K915|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CAH-1|TrEMBL
MSLLKTALREHHFVCVMEFVPKASAERFAALQAIMDRAQLCGWPMTVAIGDRVGSPLDMS
PLDALASFDRPVPALPHFSGKDRERHHLLAQLQRMEAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQAAPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMREMLEAETAQSK
AFAQSRSVDRLALQIIGTKLMGYAGVHLSGIHDLKQLLALEARLAYWQTHVHTLEQWAPA
WQASWQMPGLPAVTFHPPQANWRQGESRVDASFKEKARYHLMHGMHGLLFSRRNSLSKAF
GWAVRQPLWTTRLGAQVLHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVGQTAVLRERLIPCIEEQTRHRSSWPQWFAPPSP
RRVSPQPAPRTQPES
>A0A1X1EZL9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea cypripedii|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPGTPEMEETLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWDSGIRHIVALRGD
LPPGAGKPEMYGSDLVELLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMNAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGIAV
>A0A2H5EUW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus zhejiangensis|TrEMBL
MTTPTITTAPKISFEFFPPKTLEASFALWETARALAPMEPDFVSVTYGAGGTTRQLTHEA
VTTIQKNYGVTVAAHLTCVDASREETLAIVQSYADAGVREIVALRGDAPKGADRFTPHPE
GFANSIELIEAIAARGDMTIRVGAYPEPHPDTQGGTDADVAWLKRKIDAGATSAITQFFF
EAETFFRFRDKCEKAGITAPIIPGILPIQSWAGAKRFAAMCGTSVPQWADDAFTAAARDG
EGREALLATAVCTELCDNLLKGGVDRLHFYTLNRPGLTRDVCAALGIQPVRELKAVA
>A0A444JRS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium chitinilyticum|TrEMBL
MKCDAYKSLGGEGFREPDMESDIEPRLLQLLAEASLEATPKQVLKLHTAPDWLSAGTWVY
VPFLPKGRFEETFEACERLLLWGMVPIPHIPARAVPSEACLHRWLSSLTHIGVYNILLIA
GERKPPAGPFSNTLALLASGALAKHPLRGIGVAGHPEGHPHATSYELTNALAFKREYAET
NQLNMWVVTQFSFDADIFIQWLECYRELLGSLPVYLGMPGPTQLKNLLFYAAQCGVVESV
AALRRNLKTTQLLKPWTPDLLVQEMARYQTINAGTPFQGIHLYPFGGLKQSAKWLRGAH
>A0A1G1AUD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylophilales bacterium RIFCSPHIGHO2_02_FULL_57_10|TrEMBL
MTTNRIFSFEFFPPKTPEGMAKLREARRQLAQLHPKFFSVTFGAGGSTRDRTLETVLEIR
AEGFEAAPHLSCISSTRDEIRALLEEYRSHDIHHIVALRGDLPSGEVTGSDFRYANELVE
FIRQETGDWFEIEVAAYPEIHPEAPSAKADLQNFRRKVKAGANAAITQYFYNADAYFRFM
EECDGMGITVPVYPGIMPIYNFAQLSRFSAMCGADIPRWLRMRMLDYGDDLASVRALGLD
VVTELCDRLLAGGAPGLHFYTMNQAGAISTIWQRLGL
>A0A1G1JQC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica bacterium RIFCSPHIGHO2_02_FULL_51_18|TrEMBL
MEFAETLKRPRFVVTAELGPPKGTRLESFFKQAAYLKNNVHAANVTDQQSALMKLGSIAA
CHLLKDFGIEPIMQMTCRDKNRIALQSDLLSASVLGISNVLVLSGDPITIGDHPEAKPVF
DVDSADFISVIKKLGEGFDMTGHRLDGAPQFWVGAAMNPCVDNLDVEIAKTRKKIERGAD
FFQTQGVFDLGRFKKFMDRYHTEGFKVPVLAGTLLLKSAKMANFMNEKIPGIFIPTQMIR
RLEGTQDPKKECVRIACEIIEAVKSQVQGVHLMAIGWEELIPDIVSHSNIKP
>B6WAM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerococcus hydrogenalis DSM 7454|TrEMBL
MNIGSKDCVLSFEVFPPRKNLPIESIYNTIDRLIDLKPESISVTYGAAGNDTSKRTFELA
GQIKNMV
>A0A658QQ38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caballeronia concitans|TrEMBL
MKPIELSFEFFPPKTQEGVDKLRASRAQLAKLSPKFVSVTFGAGGSTQQGTLDTVLEMAA
EGFEAAPHLSCIGSSKESLRSILGAYREHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQEHGDWFHIEVAAYPEFHPQARSPRVDMENFARKVKAGANAAITQYFFNADAYFEFVD
EARKLGVDVPITPGIMPITNFSQLMRFSDMCGAEVPKWIARRLESFGDDRESIRAFGLDV
VTGLCRRLVDDGAPGLHFYTLNGAAATKTICERLGFKSA
>A0A836G2W6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acromyrmex heyeri|TrEMBL
MCERNDADGNDNPSTPDFHIENPRKTVVDLRQLLKDKISKNEIFCSFEIVSTRKSGAFYR
RIHIDMEEYSPLFYALTWHNEAASDNDGYLPLDLVENFPANTLLHLAAKSLKRDEVIYIL
KKAIAFGIINIFALRGDSLSENGDFEHAADLVVFIRQRFGNTFCVCVAGYPQMHPESSSK
KLDLHYLKAKVEAGADFIITQICFDSRVLINFVRDCREIGIQIPILPGILTPTNHACLEK
MIDICRLDVPIKIKEDLARMKDDDQAVRKYSVDLIVQIITDVIRNGATYGFHLFTLNRLS
LVTEICKRIESFKAENL
>A0A6M1M170|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. DB0501|TrEMBL
MFATSFRPSRESCRPIRVSFEFFPPKTAEMEATLWSSIERLAPLGPSFVSVTYGAGGSTR
ERTHNTVARLVRETDLKPAAHLTCVAATKGEVDDVVRAYHEAGVRHIVALRGDPADGVGS
AYAPHPGGYERSCDLVAGIKRVGDFEVSVSAYPERHPEAGSLDQDLDALKAKVDCGADRA
ISQFFFENDLFFRYLDRVRARGITIPIIPGILPVQNFKQAANFARRTGASVPDWLAARFE
GLDDDVATRKLVAAAVAAEQVLDLVDRGITDFHFYTMNRADLVYAICHLLGLRAAPVAAE
KAAA
>A0A8I1BT41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus hauseri|TrEMBL
MSFYHASQHEALNQNLAELDGQIQVSFEFFPPRTEEMENTLWQSLARLNTLKPSFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASREELQHIAQDYWQNGIRHIVALRGD
LPDNTQKPDMYATDLVHLLKGVGDFDISVAAYPEVHPEAKSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVTNFKQLKRFAGLTNVKIPGWMHKMFD
GLDNDPETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPELVQA
>A0A352NAI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaeria bacterium|TrEMBL
MKQSLEKTLASRISIFDGAMGTEIYKRNFFVNTCFDELCLSAPKIIGQIHKEYSDAGADV
LTTNTFGANFNKLSHFGLGDKVREINKVAVKLARENGKDDTLVAGSVGPIGKIHHHEKNS
AEQVVEMLAEQISALEEAGADFIIFETLPTVADAEFAFRAVNKNSKIPYVLSFTLDDNSE
TVKGEPVQSLINVFKDGTRKPAAVGLNCGAGPEGMLSSVEKLVQQTNLPIIVQPNAGMPK
NVGGRLIYMASPEYFTTYAIRFVNMGVRGVGGCCGTGPDHIRDIARSIRPLAKTAALEKI
IVKTLEEHLQAPVPMEKKSRLAAKFAKGEWIATVEIVPPKGYDLEQTIQKSKQCKDAGID
AINIPDGPRASSRMSPIVTAAKIQQEAGIETILHFCCRDRNLIGMQSDLLGCAALNINNI
LFITGDPPKLGDYPFASAVFDVDSIGMAKIQSRLNRGVDIGGNSIKEPTKALIGVGADPN
AIDMEREIRRTREKIAAGAEFIITQPVFAVEPLIKFIEKISDLKIPVIAGIWPLASFRNA
EFMKNEVPGVVVPDSIMDRMAKAKTKEEQRLEGIRIAKESIEKIRSHIRGIQVSAPFGNV
QTALEVIK
>A0A0P7XWQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saliniramus fredricksonii|TrEMBL
MDGFREFQAITGDAAPLTRAGRMARLLADASIEIAPRQIAEGIPAPGALDPIGEVFVPFL
PGADFDQTLDACRDLSLRGFTPVPHLPARAVPDNDTLARFLDGLAAHDVTRLLLIAGDAP
RPVGPFADTLGLLDMPQFADAGLTRFHVAGHPEGHPHADEATLMAALRYKQAHARAHGLS
LTIVTQFSFDAAPVIAWCARLSAAGIDAPVRIGIPAPVGMGTLIRFAMRCGVGASARLLG
RRPDALQMLKRFDPLPLIAGFAGSDDANPPTNLAGVHLYCFGGAAQALSWRAQALDDLRA
TAQRETAHVEDAAS
>A0A7W3FP85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas tumulicola|TrEMBL
MTSLSFEFYPPKTDDQRAQLDRTARKLRAFGPEYVSCTFGAGGSTLSYTSETVRHLKQHH
GFDAAPHLSCVGGSRQEIRELLKLYRAIGCTRIVALRGDLPSGMGHPGDLRYAAELIEFI
RAEHGDAFRIEVGAYPETHPQASDALADLKHFKSKVDAGADAAITQYFYNADAYFHFVDA
VRRLGVTVPIVPGIMPVSNFSQLRRFSEQCGAEIPRWIGRKMQAYGDDSESIRAFGAEVV
AQLCQRLTEGGAPGLHFYTLNLARPTTSVLKLLHG
>A0A7X8U4U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MMKSRLDQILQSGHFAVTAEIGPPKSCDPAFVEKKADILKGYADAFNITDNQTAIVRMSS
IAAGVLVRQKGLEPVIQMTCRDRNRIGLQSDLLGAAALGIKNVLCLTGDHQSFGNHPQAK
NVFDLDSIQLIKAVKDLRDEGRFICGEEMKVKPDFFIGCVENPFADPFEFRVLRLQKKVE
AGADFVQTQCVLEMNRFREFMQQAHDQGLTERVAVLAGVMPVKSGKMARYMQKNVAGMMV
PDELCDRLEKAHDPQEEAINIVVEQIAELREIPGVKGVHIMAVAWEEAVPEIIRRGGLFP
RPSA
>A0A7X9EW77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonadaceae bacterium|TrEMBL
MIDNKNFFIFDGAFGTYYANICKNPLSPCELANIHDQNTVLNIHREYIAAGCQAIRTNTF
AANRVTMKNDLPVLKEVIRQGYRLAQESALGTEVMVFADVGPIARQFEEDLWEGYQEIVD
EFLSLGASHFIFETFSSDEYLPELCAYIKEQNPQAYILVEFSVSPEGFTRIGLPGKKLLY
NMFETSVIDAGGFNCFSGPHHLLEFIKTFDIQNRTVSIMPNSGYPTIIDNRTFFENTKEY
FAAKMLDIAKHGVRILGGCCGTTPEYIREMVARLQHIIPSETKYEVQAEKTSINRIESPN
ILVEKLKRGEKVIAVELDPPVDTDIAFFMDSARLLKSSGVDAITIADCPLARARVDSSLM
ACKIKREVDITPIPHLTCRDRNINATKALLLGLNIEGINNVLIVTGDPIPSAQREEIQGI
FDFNSAILANYISNLNETVFSSPFNICAALNVNSKNFEVQLGRAQKKIDNGAAVFLTQPV
LSRRAVENIALARERLAARILGGILPIVSYKNACFVNNEISGISVADEIVEQYRGLSKEE
GGKLAVEISNQMVRSVYPFVDGFYLITPFKRIDLVVEIIKYIQSLEP
>Q1H4X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875)|TrEMBL
MKTEPTISFEFFPPKTAEGMAKLRVARDQLAAFNPKFFSVTFGAGGSTRDRTLETVIDIQ
QAGYEGAPHLSCISADKAEIRTLLTQYKTQGIKRLVALRGDIPSGEVSTGDFRYASELVA
FIREETGDWFEIEVAAYPEFHPESSSPSADIRHFKQKVDAGANSAITQYFYNADAYFRFV
DQCEKSAVDIPIVPGVMPIYNFTQLARFSSVCGAEIPRWLRLRLQDYGDDLASLRAFGTE
VVEDLCEQLLAGGAPGLHFYTLNQAGTIASILEQLGAGDK
>A0A1V2RRC4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MP131-18|TrEMBL
MTGRAQTVRELLAAGERSFSFEFSPPKTEKGERTLWNAIRRVEAVAPTFVSVTYGAGGSS
RERTVRATERIATDTTLTPVAHLTAVNHSVAELRNIVGQYAGAGIRNMLALRGDPPGDPM
GEWTRHPEGVGYAAELVALIKEAGDFCVGVAAFPEMHPRSVDWETDIRHFVNKCRAGADF
AITQMFFYPEDYLRLRDRVAAAGCETPIIPEIMPITNVRQIERFTQLSNAAFPPELERRI
HAVKDDPMAVRSVGIDFATELCARLMDEDIPGLHFITLNTSTHSTATLDVYRNLGLDQRT
>A0A348XLP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaeria bacterium|TrEMBL
KTVDSKIAFVSEMAESGLADAIDITDGSRGIPLMPPGDFAMLCRQGMADPSALEIIPHFT
SRDLNTLGIQSRLIGYHWNHLRNVLFITGDPPKMAPDYPASTGVFDLDSVELARMTHLGL
NAGLDFGGRPLSKQSLPCQFTIGSGFEPEAVDLDAEVQKLERKIDAGVDYFMTQPAFHRE
PLDVLTPYRDRTKVLVGVMVLSSLAQAQRIAAVPGVVLPRHILDTLAQYDSAEDQAKAGM
DLAVAQAAWVRSNGWDGLYIMAPGSHKKILDILRSSQS
>A0A2V5ISP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus violaceofuscus (strain CBS 115571)|TrEMBL
MEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGST
AQRSLELAEICQRQLQLTTCLHLTCTNMSRALVDQALEEAKVLGIRNILALRGDPPRSEE
YNMHGEDDSNKDFTFAVDLVRYIRKHHGDYFCIGVAAYPEGHPADNFQDGQDPARDVPYL
VEKTQAGADFIMTQLTYDIDAYTKFENMLRNHESGAFKTIPIIPGLMPLHSYKILTRVTK
LSHVKIPPHILSKLEEIKHDDDAVKRAGVDIVCDLVDGIRSIPTPGLRGFHFYTLNLEKT
VSFLLERCDLIGPYTEYDEPIEDSAAYSAARLETPALALASRRSSVSSMPHNRVIVDKLQ
PSDVSSRESVSHEATALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARS
PAFGEIDGYGPSLHILPAVAHKVWGYPVTRDDISALFRRHVSGELYIVPWSEGGAEEGSG
TLNAETEIIRPELLRLIDQRGWWTLASQPAINGVRSDDPIFGWGPPGEGFVFQKPFVEFF
CPSADYQTVLKPLFERHGHERLAWFATNARGDFESSLPGSNAEDPDPIDINPANVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDATKNDVWLVCVV
GQEFGAGTEVGSKEEEAETKWMWRELAGC
>A0A5D4XP66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Luteimonas sp. XBU10|TrEMBL
MTPISFEFYPPKTDEQRAQLDRTVARLKEHAPEYVSCTFGAGGSTLSYTADTVQHLLQAH
GLDAAPHLSCVGGTRDEIAELLARYRELGCRRIVALRGDLPSGMGHPGDLRYASDLIAFI
RERHGDHFHIEVGAYPEMHPQAEDALADLRHFKAKIDAGADAAITQYFYNADAYFHFVDA
VRALGVEAPIVPGIMPISNYSQLRRFSEQCGAEIPRWISKKMQAFGDDADSIREFGADVV
ARLCRQLLAGGAPALHFYTLNLARPTQAVLARMA
>A0A2W6YQP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudanabaena sp|TrEMBL
MPSDQTFNQFRQAIASKEFLITAEVSPPKGCDPTHMLEQAQVLKGRVHAINITDSSRAVM
SMSPVTASVLIQQRLGIETICQLACRDRNRIALQGDLLGAAAMGINNILALTGDPVKAGD
SPKARSVFDYESVRLLQLIQKLNQGLDANDKALPNQGTALLAGAAIDPQSPSWSGLEKRF
ERKLNAGAQFFQSQLITDFDRLDKFMQQIASQSDKPVLAGIFLIKSAKNAQFLNKFVPGV
QIPDRIIERLAQAKSPLQEGIAIAAEQIQIARQICQGVHIMAIKAEHLIPEILDRAAIK
>A0A3N2FQ30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cellulomonas sp. PhB150|TrEMBL
MNHVADLVSEHPRVRRVSAATVEPRTPAVHAAPALRPLASVDRPTVSFELFPPRNPHAAP
RLWETIRAIEDVRPDFVSVTYGASGKTRETSRTLVTQLLRETTLNPIAHLTCVGTSRAEV
TAIVEEFLDEGVRSFLALRGDPPVDQPDWQPHPEGLNTAGELVELLREIESQRCIASPSQ
AVRARVRPLSISVAAFPRGNAATGGTRAQDVASLLAKQEAGADFAITQVFFDADAYLGLV
AEAREAGVVIPIIPGIIPTTDPARLLRVQELTGVPVPRSLLDLLGNADGEADQHRRGIRA
GIDLINGVLDGGAPGVHVYTFNKHHAALDLLEGAQLHGGAGTSSRTGAAPDPVPSVPTTP
EG
>L8M4P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenococcus sp. PCC 7305|TrEMBL
MTNHLRTAVSNKEFLVTAEVAPPKGGNPARMLEMAKLLKNRVHAVNVTDGSRAVLRMSSL
AASVVLLQNGIEPVCQVACRDRNIIGLQADLMGAQALGITNVLALTGDPVKAGDHKQAKP
VFDLESVRLLKVIEKLNNGCDFNDKTLPDEPLDLFAGAAVDPQLKSWSGLKSRFERKLAA
GAQFFQSQMITDFDRLEKFMSEIASVSDKPILAGIFLLKSAKNAQFINRCVPGVNIPDSI
IQRLADAKEPLEEGIAIAAEQVQQAKDICQGVHLMAVKREDLIPQILDRAGVKSVISDQL
SPFEDKSVNSKKFSIIPNKLQVTH
>A0A2W7A5M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudanabaena sp|TrEMBL
MIEPPQPIFEQPEKLFTKFRRAIASKEFLITAEVSPPKGSDPSHMLEQTRSLKGRVHAVN
ITDSSRAVMSMSPVAASVLIQQQIGIETVCQIACRDRNRIALQGDLFGAAALGITNILAL
TGDPVQAGDSPDARSVFDYESVRLLQLIQKLNQGLDANGKVLPNQGTNFLAGAAVDPQSP
SWSGLQKRFERKINAGAQFFQSQLITDFDRLDKFVNQIANQSDKPILAGIFLIKSAKNAL
FLNKFVPGVKIPEHIIDRLAQAKSPLQEGIAIASEQIQTARQICQGVHIMAIKAEHLIPE
ILDRAGIAIL
>A0A0D9NUY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium anisopliae BRIP 53293|TrEMBL
MDKITDKIAALPADREYFSLEFFPPKTAMGFSNLRHRLQRMEQALKPLFVNVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSKRLVDKALEDAKALGIRNILALRGDPPRKEE
YCDAEDSEDDGQQDFTWAIDLVKYIRRKHGDYFCIGVAAYPEGHSDESHPQDQSLEHDLP
YLVDKVQAGADFIMTQLFFDISAYDHFEKTLREHPSGAFKTIPILPGLMPIQSYQMIKRT
TKLSHAKMPPAIMDRLDAVRGDDEKVKLVGVDIVSELIDQIRKIKNRTPGRRGFHFYTLN
LEKAVSFIVERTGLIPRESDNEEALIDDGTLAPPAIQVNGTRASTHSRTSRRHSSVGSDP
YNRVIVAGQPPSHPEWEATGQEAGVPAESINSRANTLAISEGEGVLGREATWDDFPNGRF
GDSRSPAYGEIDGYGVSLHMSVNQAVTLWGSPTSRQDVNNVFVRHIKGEISAIPWSEEGL
SPESSTIQSRLVEMNGKGWLTVASQPAVNGISSSDRTFGWGPVNGFVFQKAFAEFFLPSA
DWHMLAEKLKGSDYFDSVCFYAANAKGDFVSSDISGGRSTRTVAASTNAVTWGVFPGKEI
VTPTIIEEVSFKAWSEEAFGLWGEWAKVYGRGSESEKVLSGIRSDYWLVNIIHHDFIDRE
ALWKLLLE
>X0S8A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MAQSLRETLNSGKFVVTSEIGPPKGTNIEKMCHHIDMLKDKVDGLNVTDHQSSVMRFPSI
GGCLEIKERGGEPILQMTCRDRNQMALQAELLLAYTRGIRNVLCLTGDAIPVGDHKEAKG
VFELDSVQLLRAIRQMESGKDLGGNDLDGAVEFCAGAIVTPEANPIEPQLIKFEKKVEAG
AEFIQTQAIYDLDNFSKFMDYARQFPVKILAGIVLLVSARMAKYMNENVPGIFVPQNLID
ELASAPKGEALNKGIEIAGHMIAALKKDSICHGVHIMAIGREEVVPDILAAAGLSTETTS
>G8X6P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium columnare (strain ATCC 49512 / CIP 103533 / TG 44/87)|TrEMBL
MKVTEHIANASGKTQFSFEILPPLKGQNIQCIFDGIDPLMEFNPPFIDVTYHREEYEYKE
LGNGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKDGNGYASELVKQISDLNNGKYLDADLQNTNATDFCIGVAGY
PEKHIEAPSLDSDIHFLKQKIANGADYIITQMFFDNKKFFDFVSKCRKAGINVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMAVVKAKDNEAVKQIGIEWCIAQSKELVKAGIPVLH
YYSMGKAENIKAIAKEVF
>A0A6M1RQH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium daejeonense|TrEMBL
MSPDINPHDPGAPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANPHDVYERASVFD
GWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGASAMGV
QNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDQSKFLSGRKLTSPPQVFLGAA
INPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFREYMKKVRDLGLHEKCFILVGVG
PLASAKTAKWIRSNVPGIHIPDAVIKRLEGAEDQKKEGKQLCIDIINEVKEIEGISGVHV
MAYRQEEYVAEIVHESGVLKGRKPWKREASPVDALVAERLEAIRAEKLEDQQQLAEKAAS
HPH
>A0A1G6L7W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus sp. YR651|TrEMBL
MTDRYFSFEFFPPKTAEGAEKLRNTRAQLAPLQPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSTRDSIRQILGKYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQARSPRHDLDNFVRKVRAGADSAITQYFYNADAYFRFVD
DVRALGVDVPIVAGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDKESIRAFGLDV
VTGLCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A7Y7TC58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio sp. Scap16|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKNQTGLVAAPHLTCIDASREELIQIADDYWANGIESIVALRGD
IPAGGGAPEMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQSDLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGVDVEIVPGILPVSNFKQASRFAAMNNVKVPGWMAKQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQVAAL
>B4PF37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila yakuba|TrEMBL
MHAIQVPAGGSPLPAAATSYIPCVTFAPGQNESGMAEQRIGTLVAERTAQRRLFYGIELL
ASGPGGRPTCLDFHHFLPLLPTFVSVVWLGQRYWDVEPVGQVESLQLAQHLATRIPVLPH
VSAYRMSRQRLDQFLELNFSSVLAVRGDQVHEEQEFLISQPMVEQSRRQRGENISVCVPG
YPEGYTSLGDMPQNAAKNMQFLKAKIDAGADCIITQICYRPEVIVQFVKDCRAAGIAVPI
VVGLMSHESFRSYSMIEQIAGVQLPDDLRAELDQLHSAHVKDMKSGQDLIRRFFVGLTVR
TVRHVLDADVGIWGFHFFTLNRFKPVQAVLQELRDLNLLKDSEKE
>A0A0F9FNQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MDRIGIVVKADDAAQRKADELESWLTKRGIEVIQKKNFPHGRKGLHHNKTFAPSDLFCIF
VLGGDGTFLSAVRWIGNQKIPVIGVKFGETGFLAETAENDLFTVTELILNRKFSIEPRMR
LLVKVIRGETERASETVLNDVVVNKGALARLAYIKTYLDDYNLTTYRADGLIVATPTGST
AYSLAAGGPIIHPAVPGIVMTPICPFTLTNRPLIVPDSVTITIRLAKKIEAGADFIQTQA
VYDLVRFGEAIKRAEDMGLCEKTAILPGIIVPRSAGMLKYMNANVPGIEVPDEMIDRMKS
AADPKAEGIKIVLELIEGVKAMSGIKGVHLQAIECEQILPQVIEDAGLLPRPKI
>A0A0F9PMS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSPVISEKWYGGRIKVAEKKVYSKLGEMLAKGEFILTGELEPEKTCDLSNTIQEAKEMAP
YIVAANVTDSPLSIVTINSMAAAHVIQRQTGLECVWQLTVRDSNKIGLAGQIMGAGALGL
SNMLSLTGDHTALGDCPESKPVFDLDSATLIKLVREMVDKGSINGHEIETPPKLHVGAAA
NPNADPMEAEILKIGRKAEAGVEFLQTQVVYDIDMTIEFLRGIQKYNVPILLGIFPMKSY
GMAKGFDMFVPGVDVPKEILERWKSVKTNVTDKKEQKQTYDQLNYEFFKPFITELKTKGL
LAGVHCMAVHYTRIFPKLIEVIKG
>A0A7W9Q5B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces zagrosensis|TrEMBL
MALGTASTRTDHARTVRDLLASGEQSYSFEFSAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGSSREGTVRATERIATDTTLTPVAHLTAVNHSLSELRNVIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGIGYAAELVELIKESGDFCVGVAAFPEMHPRSQDWDADVRHFVA
KCRAGADFAITQMFFYPEDYLRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELASRILAVKDDPAAVRSIGIDYATELCARLTAEEIPGLHFITLNHSTATLEIYENLG
LHQRS
>X0YI88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MVEPFRKILKSDKFFITAEIGPVKGTNVQKMIDNIEILKDKVDALNVTDNQSAVMRYPSL
GTCLLIKEHGGKPIFQITCRDRNRLSIQADLLFAFSRGIESVLCLTGDSLKMGDHLEAKP
VCDIDSVQLIQLIHNLNSGKDLSGNNLDGGVDFCIGASATSSADPIEPQLIKFEKKLKAG
IDFVQAQAVYNLDELKRFVDYSRNINKNVKILAGIVLLVSAGMAKWMNENIPGIFVPQNL
INELAEVPKGEGLSKGIEIAGNLIKRIKDEKICDGVHIMAIGKEEKVPDILKAAGILKD
>A0A345NZI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina sp. PTS2304|TrEMBL
MSLLEKLQTNVLTADGAMGTILYSYGIDYCYEELNIEKPEIVEKIHQDYITAGADVIQTN
TYSANAVKLARYGLESRVTEFNKAAIQIAKRAAAPGGQFVLGTIGGLRGIRKSDASLDEI
QKVVLEQANALLSGDPDGLLLETYYDFEELSSVVTTLRQITDVPLIAQVSMHDPGVLQNG
LSLNDALHQLESLGANIVGVNCRLGPYHTIQAFENVTLPNKAFLSAFPNASLLDVEDGRI
VYESEAEYFGRAAVLLRDQGVRLIGGCCGTTPKHIKAAKTRLEGLAPVTEKVVAPAKPII
IQEAGPVKHQPLHEKAKTERTVIVELDTPRHLETEDYIKGANLLYDAGVDAVTMADNSLA
SPRISNMAMGSIIKMQHNIRPLVHLTCRDHNLIGLQSHLMGLDALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELLQLIKQLNEGISFSGKPLRKKANFSVSAAFNPNVRVIERAVQR
LEKKIEAGADYFITQPVYTKEKIIDVYEATKHLDTPIFIGIMPLTNIRNAEFLHHEVPGI
KLSEEVLERMRECGDDREQSTATGIEIAKELIETAAKYFNGIYLITPFLRYDMTLELYEY
IKELDEKKERELTHAETSY
>A0A0F9UNQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSRPNPLSTSGIDVSFEFFPPKTEKMEENLWRAIERLAPLGPSFVSVTYGAGGSTRERTH
QTIERLLKETRLTPAAHLTCVDATKEEVDAVVRQYWETGVRHFVALRGDSQAGVGGEYVA
HKDGYRNAVELVAGLKAFADFEISVAAYPEKHPESPDFATDIDLLKRKVDNGATRAITQF
FFDNDTFERYVERVRRAGIYIPIVPGIVPIHDFTKVARFSQATGASIPAWLAARFEGLED
DEQTRSHVAAAVCADQVLDLQKRGISDFHFYTMNRADLVYSICHILGLRADEASAPAGSA
SEAAAA
>A0A0F9P693|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSKKLTVSCEFFPPKTDKGAANLRRVRDALLPLKPEFYSVTFGAGGSTQDNTFDAVTDIQ
RHAQTTHVDAAPHLSCVGSTAEKLRALLNAYQENNIHRIVALRGDLPSGMRDPGDFRYAN
ELVEFIRKETGDYFTIEVAAYPEVHPQAQSAEVDLENFKRKVDAGANSAITQYFYNIDAY
RYFVDNCQSNGIDIPIIPGIMPINNYAQLARFSSGCGAEIPRWLRKRLESFYDDTESMKA
FTRSLNPFTSCVI
>A0A8H9HIZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kitasatospora psammotica|TrEMBL
MALGIASTRPDRALTVRELLAAGKRSFSFEFMPPRTEVGEQKLWDAIRRLEPLDPNFVCM
TYGAGGSSRERTVNMVGRIATETTLTPVAHLTAVDHSIAELRNIIGQYADQGVRNVLAVR
GDPPGDPMGEWVRHPEGVTYAYELVELIKGIGDFCVGVAASPNMHPRSTDWDEDIRHFTA
KIRSGADYAITQMFFEVDDYLRFRDRVTAAGCETPIIPEIMPVTNAKQLERFPQLSGSAF
PANLEARLRAVVDDPAALRAIGMEHATAMAERLLAEGAPGLHFITLNHSTATLEIYQNLG
LHQRP
>X1Q989|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine sediment metagenome|TrEMBL
MSLQSVLESGKFVVTAEVGPLKGTDTTEIIEVAELLRGRIDATNVTDQQSSVMRLGSLAT
CHLLKERGLDPVFQMTCRDRNRLALQSDLLSAYVLGIENVLAITGDLPSLGDHPQAKPVY
DLDSVQLLWVIKRLNEGYDMVGNELKGKPNFFPGAVVNPGADTEAAFELQLIKMEKKIAA
GARFFQTQAIYDIDTFTKFMKRVEGFNIPILAGIIPLKSAGMARFMNKNVAGVFVPEELI
DKMAKTEDKARTGIEIAANLIKELKGMCHGVHIMAIGWEKRVPAILDAAGL
>A0A3M7DCC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hortaea werneckii|TrEMBL
MDKLTDKIAALPPDANYFSLEFFPPKTQQGFANLHARLSRMAQALRPLFVNVTWGAGGST
SAKSLALAELTQRSLQLTTCLHLTCTNMSRKLVDEALEQAKVLGVRNILALRGDPPRSDE
YNDPNNPLSEQDDSNRDFTWAVDLVRYIRKQYGDYFCIGVAGYPEGHSDQSHPEHQSVEH
DLASLVEKTAAGADFIMTQLFFDVEAYNDYEKRLRSHESGLFKTIPIIPGLMPVQSYQIL
RRTTKLSHASLPPDVLSRMEPIKADDEAVKRVGVDVLCEMVENMRRHESPCARGFHFYTL
NLEKVVTQILERTGLIPPATPVIKSADRNGIAEQAVAEEESDGFLMVEDAKRNRQRRKSS
NRNSMPQNRVVVSRRSSTSSSKTQAYEAPEDEAGVPPVNSRANTLAISEGQGSAGREATW
DDFPNGRWGDVRSPAYGEIDGYGVSLHASIPEANRLWGQPKSTDDICTIFRRHLQGEIEA
MPWSEEPLQPETLTIKKELLSLINKGWWTVASQPAVNGVRSNDPIYGWGPKNGFVFQKPF
VELFLPSADWQRLKPILQSDDQVTYYAGNAAGDFQSSDENSVNPVTWGTFAGKEIITPTI
IEGDSFKAWLEEAFGIWAEWQRVYQPGSESSRLLEHTRKDCWLVSIIHHGYLEKGALWDA
LIAA
>A0A1W0D560|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromobacterium haemolyticum|TrEMBL
MTAQSRTFSFEFFPPKTPEGIAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLATVLEI
RSEGHAAAPHLSCIGSTRENIGAILNEYRNNGIRHIVALRGDIPSGMVAAGEFRYANELV
EFIRAEHGDHFHIEVAAYPEFHPQARSAEDDLNNFVRKVHAGANSAMTQYFFNADAYFRF
VDEVQGRGVNIPIVPGIMPISNFGQLCRFSDMCGAEVPRWLRQRMQAYYDDSASIRALGL
DVVTELCDRLLQHGAPGLHFYTLNQAGLVSTIWQRLGL
>A0A0M0TBR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus sp. GDc328|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLDAAPHLTCIDANREELRDIAHDYWQNGIRHIVALRGD
LPTHGCKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATLTNVRIPSWMTRMFD
GLDDDPESRNLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPC
>S2Z1X0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. HGB0020|TrEMBL
MNSFNTASAAVSTSLLEDFSLEMTGKDVSKLEEARDAIPRGTRVNVTFLGNEDLEMRLAA
ARAVKQLGFVPVPHFSARRLGSKADFEGFLAGLRTDGTCDNVFAVGGDPTRPEGPYEDSL
SLIDTGLLPEYGVRHVGISGYPEGHPAIAADVLWSALRDKSAALAAQGLEGSVITQFGFD
VDPVLAWIERVRGMGIVLPVRIGVPGPAGVRRLMSYAARFGVGTSAAIAKKYGLSLTNLM
GTAGPDRFLRALAEGYEPARHGEVKVHFYTFGGLRATAEWVARFRKELQA
>A0A3B7D6M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium sp. A1-2|TrEMBL
MPPDHQSLVDALRGSVPSYSFEFFPPKDDAGEAVLWQTIADLEPLEPTFVSVTYGAGGTS
QERTVRITARIAEQTRMRPVGHLTLVAQTRGEIESVLKQYAASGVDNVLALRGDPKGGPR
APWESHPDGMDHALDLVELASGLGGFRIGVAAFPEGHPDAKSLQHDAEVLVAKAEAGAEY
AITQLFFRATDYFSLVERVRAMGCDMPIVPGIMPILNFAQVARMAELSGAELPREVLDEV
EPIQDDQAAVRSKGIELATTLCRDLLAGGAPGLHFITLNRSKATREIFDSLRSDGLV
>U7V7W4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia aeria F0184|TrEMBL
MKMTTVHPALSYELYPPRSHASCDSLLKTIAELEQTNPDYVSVTYSGDAQRRQKTLALLD
HLVHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLALRGDIPPENTRSLELPFAR
YLVELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQ
VFFETERYSGLVDAARLAGVEMPIIPGIMPVTSLTRLTKLCELAGLEVPRELAHRLETAS
EPREMHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLS
DLQYL
>A0A2R5GQV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hondaea fermentalgiana|TrEMBL
MEPLATAQTTEDADKVIQRIAEMGEALQPTFVSLTWRSAYKDEDVWLKIGSIVQKQLGIA
VLLHLTCHLPREDLVRVLRKAREAGIRNVLALRGDAPHVTAGAANASAGPQQPGWRAVKN
GFRNAIELVHLIRAEHGDYFCVGVAGYPEVHTSSWNSPVLPPSAQAREQDLIRLKDKVDA
GADFVITQFFYEVDVFFKFRERCQDLGINVPIIPGYAPIQNYSSFQRFKSWVRPQVPAQI
ETKLNEIKDDDERVQAYGVEVGVEQIRALLRRDVHAVHFFTLNLASAVTSILQRLRLRDT
SLTQPRQLPWRGLAREQEEVRPIFWAHRHSSYLSRTSAWSEFPNGRWGDARSAATFELGD
YYLASKERSNIDLRELWGVPTSPADVAAVFVRYMRGEIAQLPWCDQQLAAETETISEELC
WINRNGFLTINSQPKVNGVSSSSARYGWGGDGGVCFQKAYVEFFCSPEMWFKLRSCIDAL
PPGRLSYHAVNVAGDEFLDSDLRHREEKDHEGAVVAAHSDTSPVLASDVPARRKVSFADE
LVEAKAARPGRVNAVTWGVFPGREIIQPTVVDTESFRVWKAEAFELWLSQWAATYEESAE
GGGMTSDRDAQAVRVLRSIHDTWFLVNIVDNDYVNEESNIFEVFKTVILDEMSAKELRSR
VDSLERENAHLYRELLRARSQVDALSKSPEE
>A0A419A5E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus siganidrum|TrEMBL
MSRPAPKISFEFFPPKTLDASFRLWETARALAPLRPDFVSVTYGAGGTTRQLTHEAVTTI
NRHYGVNVAAHLTCVEATRAETLKIVQDYADAGIREIVALRGDAPKGQDRFTPHPDGFAH
SVELIEAIAARGDMTIRVGAYPEPHPDSASTDADVAWLKRKIDAGATSAITQFFFEPETF
FRFRDKCAAAGIEAPIIPGLLPIQGWAGAKRFAATCGTSIPQWAEDAFATAISEGPDSER
RLATAICTELCGKLLDGGVDRLHFYTLNRPEMTLDVCATLGIRPEPSGLEAVA
>A0A3D2FG27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp|TrEMBL
MPVPSVSFEVFPPKSIDASFRLWDTAQVLAPLGPRFFSVTYGAGGSDQHL
>A0A7Y4VLT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclobacteriaceae bacterium|TrEMBL
MKVVDHIKNANGKTLFSLEILPPLKGENIRTLFDNMDPLMEFKPPFIDVTYHREEYVYKK
KENGLLEKRSTRKRPGTVGICAAIQNHYKVDTVPHIICGGFNKEETENALIDLHFLGIDN
VLALQGDAIKSEARFVPDPDGHKYASELVEQIVKMNQGRFIDEELENASPTNFCIGVAGY
PEKHFSAPNLKIDLKYLKNKIDLGAEYIVTQMFFDNQKFFEFVAKCREIGITVPIIPGIK
PITTKTQTNVLPTIFHIDLPEELADEIEKCKDNAAVKQVGIEWTVKQSKELIKHGVPLVH
FYSMGKSDPIYKIAKQLF
>A0A2R9BUM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pan paniscus|TrEMBL
MDHRKARVLPAGHYCPSLGIWASQVGSVRSSVPPSISRNPAMVNEARGNSSLNPCLEGSA
SSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISR
FDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRLEEIT
GHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDICVAGYPK
GHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPI
QGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIQLAVSLCQELLASGLVPGLH
FYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQ
EWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVLYL
SGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVG
WGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAV
TWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLV
NLVDNDFPLDNCLWQVVEDTLELVNRPTQNARETEAP
>A0A009QIB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii 625974|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSKEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KKAKSFLIKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAEEKQVGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWNSLWQVT
TGKEFTPEITRFSCQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKAPFWENSVVAK
ALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>U1RJL4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces johnsonii F0510|TrEMBL
MIRSTIQSGRETWFDDAAATRCAGASARIDGDDVLDNEPTEPTAAIEGRNDDPGDAERAT
SRSLPTVSLELFPPRAGKAASATWGRIDRLLATGPDFVSVTYRPAFVTDPVPGSGEKGRW
QQCDAPRVRAVQEESNPSEGVLAHVLGSSAVPLMAHLTCIGYRKREAVDIITRFLRMGVR
RFLALRGDPPTGTRADDVAGELRHADALVRVIREVEADYFGDGRRHVTIAVAAYPATNDH
IEAIEVLASKQAAGADLAITQVFYDPADYVALTNAASYAGVNIPILPGVIPLTDLGRLTR
LEALTGVKVPDALRSSLGSASGATLVERGIGATLDLATALLRAGAPGLHLYTFNRTRPAL
DVISHLRLGGILAGAAPDREVRDAVDRGYLQATPGRGPSFLRCGSPGAAVSSRHPVQPHT
TITKENA
>A0A7G5DQB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MSPm1|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLLNVARQLASYNPDFFSCTYGAGGSTRDRTVNTVLQLD
GDVKVPTAPHLSCVGDSKAELRELLNLYQNAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRVETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGANSAITQYFFNADSYFY
FVERVQKLGVNIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIDSIQAFG
EQVISEMCERLLAGGAPGLHFYTLNQADPSLAIWKNLNLKR
>A0A1U7R216|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesocricetus auratus|TrEMBL
MSRREAKVLPAGHCYPSLGMWASEAGCVRLSVPPSISRNPAMVNEGSSSGSESSKDSSRC
STPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFLD
VTWHPAGDPGSDKETSSMMIASTAVNYCGVETILHMTCCQQRQEEITGHLHKAKQLGLKN
IMALRGDPVGDHWETEEGGFDYATDLVKHIRSEFGDYFDICVAGYPKGHPEAESFEEDLK
HLKEKVSAGADFIITQLFFEANTFLSFVKACTEIGISCPILPGIFPIQGYTSLRQLVKLS
KLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEV
LKQLGMWTEDPRRPLPWAVSAHPKRREEYVRPIFWASRPKSYIYRTQDWDEFPNGRWGNS
SSPAFGELKDYYLFYLKSKSPREELLKMWGEELSSEESVFKVFEHYLSGEPNQHGYTVTC
LPWNDDPLAAETSLMKEELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAY
LEFFTSREIVEALLQVLKKYELRVNFHIVDVQGKNITNAPELQPNAVTWGIFPGREIIQP
TVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFLLDNCL
WQVVEDTFELLNGHSTRGEAQAP
>A0A7Y8AD19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. IPO3778|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYHPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKQAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNAESYFY
FVERVQAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDVKSIQAFG
EQVISEMCEQLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A7Y2MZI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MHVNEIFERDSTTFSFEFFPPKSDEAWGLLFERIRVFKRLAPSFVSVTYGAGGSTREQTH
DLVVRLHEEAGLDAVPHLTCVCHREAEIDGVLRRYADAGISNILALHGDPPRGMVGYDRS
QDDFKYAADLVRHIRVFNERGEHPHPKGFGVGVAGFPEGHPETLNRLREMEYLKAKVDAG
ADYVCTQMFFDNNEFYDWRERCELAGIDVPLIAGIMPIASLRNMERMAELSGGTRFPAKL
LKGIYKRQDDPEAVAQFGVLWATEQCRDLLDHDVRGIHFYTLNRSDATRRIFETLGAKDS
TALR
>A0A7V2N3C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaerales bacterium|TrEMBL
MGRPDFIEGLCRRVVFADGAMGTMLFQHGVFLNTCFDELNLTNPKLVARVHEGYLRVGSE
LLETNTFGANAFKLARYGLADKVEAINAAGARLARDCAGDDAWIAGAVGPLGPGHIGLGT
DADEAARQAFAAQIHALTEAGVDVVLFETFGNPAELQLAIEAARTVTSLPLIAQMAVNED
HQTLLGMPIEEAIARIAAEPQVAVVGLNCSVGPSPMLESLQRIRPVTDKPLSAQPNAGLP
REVEGRRMYMSTPEYMAEYAKRFFEHGVRLIGGCCGTTPEHIRQIVKAVSAMDKAMGRPA
AEATIVQPSAEAQGVEPIPLPQKSRVGAKLATGQPVCSIELVPPRGVRLDAILEKVRLCA
AHGIDAVNIPDGPRATSRLSPMVTAVQVQQAADIEAILHVCCRDKNLIGLQSDMLGVHAM
GLRNVLLITGDPPKLGEYPDATAVFDLDAIALTRVVSRLNRGLDVAGNALDEPLALTIGV
GANPVASDRPREIDRFRRKVEAGAEYAITQPVFDVRMLFDFLDAVADHPIPVIAGIWPFT
SYKNAEFMANEVPGVVVPPALLDRMSAAKTREQGRALGVTIAREMIEQIADRVAGFAISA
PFGNVRIALAALGRLAIEAI
>A0A8J5QK85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] subhashii|TrEMBL
MATVIEKIQSLGPNEKFISFEFFPPKTDAGFRNLLARLHRMSALNPLFITVTWGAGGSTS
EKSLDLAATCQNDLGLTTVLHLTCTNTNREIIDDALERAKKAGIRNILALRGDPPRAEEY
WTPNCDFNGAVDLVKYIRERYGDYFCIGVAGYPEGHVDGSDSSGQDPKKDIPFLIEKVKA
GADYIITQLFFDVEKFVQYEQLLQSYDELKNIPLIPGLMPITTYKVFTRASRLSHASIPQ
DILRILDQVSHDDDAVKTLGVQFVNEIISNINNQIGSRIKGYHFYCLNLEKAVVSIVDQS
EVLRSILEGPTTTTDREDAIASDSDSDIDMKDVVIRPNRRRSSIINENEIAETASASKVL
IGKALLKDKQILVDISTGKGALGKDATWDDFPNGRFGDSNSPAYGEIDGYGPNLKIHTPA
EAAMKWGTPETITDLTQVFIDYLSGKIDILPWTDSSLSSETALIQEELFNLNKKGWFSLA
SQPAVNGCKSTDRIFGWGPKNGIIYQKAFVELFIPKKAWELELKPKLKTYFDKKVMTYYA
GNKDGSIESNLGIGSQAHYTKSAVTWGVFPSKEVLQPTIIDYESFKAWNEEAFSLWVQWA
RCYKIDSKSYELLNSVYNDYVLISLVHHEFPDEQGLWDALLDE
>A0A521JR36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MQIASLFQKNRAVLSLEVFPPKKTSPIDTIYKTLDNLKDLQPDFISVTYGAGGNAGDTST
ADIASDILYKYGILPLAHLTCVNYSRQEIGQILDSLKEKEIKNILALRGDINPDISPKKE
FSYASELVAYIKSKGDFYVSGACYPEGHVDAEDIDKDIEHLKLKVDAGAQHLISQLFFDN
DYFYRFIEKVRKVGITVPIQAGIMPVINKSQIERMVTLCGASLPPKFTKMMQRFEHSPEA
IKEAGIAYAVDQIVDLVSQGVDGIHLYTMNNAYVARRITDCIKGIIHS
>A0A165QBZ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Daedalea quercina L-15889|TrEMBL
MKISQKIAQAEKEDRIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSELVKTCQKLIGVETCMHLTCTNMPKEKVDIALKEAKAHGCRNILALRGDPPMGKDE
WEAVEGGFVHGIDLVRHIRANYGDYFDIAVAGFPQHVQLPPAELAAELAFLKEKVGAGAE
FIFTQMFYDVEIFIAWVKAVRAAGITVPIVPGIAPIQTWNGFIKSTSLSRTEIPKPMLDA
LEPYKSNDEKVREIGTKLVAEMCKRILAEPLGIKGLHFYTMNLEKATRMLLEELSLVPRI
QTVKPLPWRQSLTPNRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQTKEQAIQLWNHPTTVVELGQLFSKFCLGQLAALPWSDQVPSSETTVIATQLA
KLNEMGFLTINSQPAVDGARSEDRIHGWGPPHGYVYQKAYLEFFVSPQLLDALLPHIERD
VNITYYVINKRGDLRTNTHSDGPNAVTWGVFPNKEIVQPTIVEAISFMAWKDEAYELGRQ
WAKYYEPGSSTRTLIDDVMDTYFLVNVVHNDYKRPEAIFEPFFKAGAEFAIAKGAVPPVL
NGH
>A0A0J0VAW2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geobacillus sp. T6|TrEMBL
KTVKRRAVSVSVQAERPAPTPLPELARTRRSVIVELDPPKQLGIDKFLAGAKALHDAGID
ALTLADNSLATPRISNAAVATIIKERIGVRPLVHMTCRDRNLIGLQSHLMGLHTLGITDV
LAITGDPSKIGDFPGATSVYDLSSFDLIRLISQFNEGLSYSGKSLGQKTNFSIGAAFNPN
VRHLDKAVERMEKKIQCGAHYFLTQPVYSEEKIVQIYEATKHLDTPIYIGIMPLVSARNA
EFLHHEVPGITLSDEIRARMAACGDDPVQAAREGIAIAKSLIDAAFDLFNGIYLITPFLR
YDMTVELVRYIHEKEAAAKERKVVHG
>A0A3C1DCG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eggerthellaceae bacterium|TrEMBL
MENRFKDALERGEFVVTCEIIPGRGAREAGQEKEFAEAKSIYATGRVHAMSITDNPGGNP
ALLADTLGKEFLDEGIVPLVHFTCKDRSRNQIISQLYGMERQGIENILFMTGDYQ
>A0A2R2W7V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frondihabitans sp. 762G35|TrEMBL
MVASTVPFSLEVFPARSSAAALALGHTVQRLAAHFPSFIAVTSGADGTSAAESADLVEYI
SRNAGVPVLAHVTTWGRSDDELRDRLRELREQGVRHILAVKGDPPRVDPGTAGDLTSADL
VAIARETFAEQPGDVTEIAVAAFPDGHPSGGGVDRDLELLLGKQRAGATRALTQVQFTAD
AYAAYLVRAREHGITIPIVPGILPVTNAGRLRRVAELTGSDAPAGLLARLEEAASPSEAE
EAGVEFATDLARDLLAAGAPGLHFYTLNLADPVLRVIAELGLTPLTPRDEFVATTTHREF
A
>A0A0V0VQB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella sp. T9|TrEMBL
LLNLKAKVDAGADFIITQLFFNEMHYFKFVSDCRKIGIVVPIIPGILPIQSYQSIMKIVQ
LSKIVIPDSVLTTLESIKENAEAVRNFGISFAVQLCRKLLNREHHVVPGLHFYTLNQEKS
ILEQIGFWKKAPVRMFPWKKHTVHSVRCREAVRPIYWTARPKSYLCRTRDWKQFPHSRWG
DVGNPAFGDLKHYLFSCIDQMDDSCALDMWDKELSTLEHVRDIFCNFIARTPNRHGHSVR
RLPWNENHLDPAADVLKNELIYYNSNGILTINCQAAVNGLPSSDPIFGWGEANGYIYQKV
NARCILISLGYLEFFASSTCTTILLNHVQNFPSINYHAINFDGSFETFNYDEDATVALTW
GVFVGQEIVQPTVANAASFRVWKVVAQLSFIQLFLFVFEQDEAFDLWQRWAGLYESGSIG
RKLLQRIHDDYRLITLIDNDYPQPCSLSALLRDVISDYIGGKNLTTDDDRLACRLALRAS
KHGITAEKEEEEEAIIE
>A0A1D8IK65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidihalobacter yilgarnensis|TrEMBL
MSHQIRHPKIYSCEFFPPKTDEAAERLQKVQMDLCALGLRFLSVTYGAGGSTQARTLNTV
LAIQRDSGIDAAPHLSCVGSTREHIRETLHIYRNHGIRHLVALRGDLPSGMHDIGEFRYA
NELVAFIREETGDHFHIEVAAYPEIHPQARSAEDDLRHFKLKVDAGADSAITQYFYNADA
YFRFVDECERMGLDLPVVPGIMPITNYTQLARFSDACGAEIPRWVRKRLEGYGDDRDSIR
AFGLDVVTALCERLLAGGAPGLHFYTMNQSEATLSLWQRLGLPMPAT
>A0A517SI32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulifigura coniformis|TrEMBL
MNIRDAYGPNRFGLSFEVFPPKSLEGDRQLATELEKLAECRPAFISCTYGAGGSTSKRTL
EWCGRIQQEFSTPAMAHLTCLNSTADSLKHWMRQAFDSGINNLMVLRGDLPRNASTGGEE
APGGLRRAHELVTLARELSDSIGIGVAGYPEKHPESPDDETDLLHLGTKVRCGADAVFTQ
LFFDNRTFLAFRDRAIRAGIQTPIVPGIMPVTEYDSLVRISSLCGSVIPDELQSGLEAAR
HDPVAQFEFGVDYAIQQCRDLIRHGVPGIHFYVLNKAAAVRLIVRELLFDARDLSPIAGR
TPGKQLASCDKDLVAARQTETWY
>A0A2E9PS36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineaceae bacterium|TrEMBL
MMATSRLERVLKSGRFAVTAELNPPDSADPESVYERAIVLAEVCDGINATDASGAHVHMS
SVGVCALLTRAGYEPVMQVSCRDRNRIAVQGDLLGAAAMGVRNVLCLTGDGVQTGDHPDA
KPVFDLDSVTLLKTARSMCEQSCFMSGRELDVPPRFFLGAAANPFVPPFDFRPHRLAKKV
RSGADFIQTQYCFDVPCLQQFMQAVRDLGLAEKVFILVGVGPIRSARAGEWMRTNVPGVH
IPDAVXARLKGVPADXQAAEGKRLCVDIIQQVREIPGXSGVXVMAYRQXELVAEXIXEXG
LLPRGGRGRKGREQTRRXAAXSLHTR
>A0A271LQA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium temperatum|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKNDEMEARLWDTVTRLQPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVDAARHEVDEVIQEFADMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWMAERFD
GLQTDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A242U2G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter pittii|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>A0A2V1NLM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. V2|TrEMBL
MALGTASTRTDRARTVRDILASGKTTYSFEFSAPKTPKGERSLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMADWIAHPSGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSDHWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEIMPVTSVRMLERLPQLSNAVI
PSALKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTASLEIYENLG
LHHPPRA
>A0A250FBU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga leadbetteri|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKIEAGADYVVTQMFFDNQKYFEFVDKAHEAGINVPIIPGIKP
IAVKKHLNLLSQAFKIDFPQELVEAVEACKHNADVKQIGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A1G1Q228|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Omnitrophica WOR_2 bacterium RIFOXYA2_FULL_38_17|TrEMBL
MKKISDIFNEKEKTFSLEIFPPKTEKGLDNLIEIIAQLCELKPDFISCTYGAGGGSREKT
LDLVEHIQNTHKVPSMAHLTCVLHSKDDIKTIVKNIASRQIKNILALRGDPPMDDPDWQP
TEENFKYSCELVSFIKENFNNYFSIGVAGFPEGHLLCKDLNRDSEFLKIKIDNGADFVIT
QFFFNNDHYFNYVKRLRKLGVTSRILPGILPITNYEGLIKFSNLCGATINAEIKDIFEPI
ADNKDATIKEGINFAIKQCKELLAGGAPGLHFYSLNKLEPTRSILEEVR
>A0A3B8SJT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MEKTLLEKLQEGTIIMDGAMGTYYAKKNGNSNEMAEWANMNNPELVVAIHKEYMEAGATI
IRTNTFAVNSVVLEIDKEEQKALIKKGYQLAKQAVTEFNKTKNSPVYIAADIGPIPVHAE
RTREEVICEYKRICNVFLEEGADIFLFETFSQIDVLKEVVFYIKEMNANACIITNFCVNK
NGYTMAGIQGNKLLKEVMNMEEISICGFNCGIGSGHMYQFLQSVEFPVNKRIAVLPNAGY
PEQLYTRMIFNNNIRYFTENMSRIKQLGVSIIGGCCGTTPEYIKALQEACSNDQISKGQV
KVRNKDIPSITNSMKEEREEGKTKKARSIFEENLENRIKDQRTFIERLESGKKVIAVELD
PPYDSNDEKIMNCVEALKNTSADIITIADSPMGRSRVDSLLMSIKIAAKHEVSVMPHVCC
RDKNMIAMRSTLLGAYVNGIRNLLVVTGDPVPSEQRLSTTNVFDYNSIQLMQFIKQMNEE
HFSEDPIQYGGALNPALGRVDKIIERMERKMEAGAKYFLTQPIYDEETIEKIHYIKEHVD
TKILCGIMPFVSYTNANFIKNEFSGIHVPDEIVSRYSKDMSKEEAEMIGASLGRDLVKKL
EPYADGYYFMIPFNRVSMFEKMNL
>A0A3Q7MXI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callorhinus ursinus|TrEMBL
MDHPTPKVLPARPRGPSLGMWALETGRVRFSVPPSIRNPAMVNEPRGDGGPPPRSEGSSS
GSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRFD
RMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQEQITGY
LHKAKRLGLKNILALRGGVEAALYSLGSCFLEGLFCPYPVGDQWEEEEGGFSYAADLVRH
IRSEFGDYFDICVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVK
ACSEIGVTCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQ
AVSLCQELLTSGLVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW
GEELTSEESVFEVFARYLSGEPNQHGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPTPEQGEEAL
>A0A352WDR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MTDIREYLRDHVLIFDGAFGTYYSQRIDQASGSCELANVDHPDLVGEIHREYLIAGAQAL
KTNTFGAYASLVGGPEKQAEIIWKGLSLAEEALRDYRELDSAPGNRPVYIFADLGPAPGD
TPEQKAEQYIQAAELFLQAGAKHFLFETQTVTDGLVEATRYIKKQRPDAFILVSFGVLPD
GYSTAGQFYRQMILEVLESGYVDLAGLNCVSSPGHMAKLLGKLPEELLLRIAAMPNAGYP
VVRGFRTFFDGSAKYFQGTMKRFLDMGIHVLGGCCGTTPDYIRGLAELAVVQVVVPHDYT
SPYHGKGENPREGEAYHGTINRLLTKLRRGKRVIAVELDSPRNAELDRFMEGAKRLQAAG
VDTLTIADCPIAQARMDSTLLACKVKRELDLDVIPHMTCRDRNVNATKALLLGGHAEGIR
NVLVITGDPIPTAERDEVKTVYQFNSRKLMSFVSSLNQEEFHPDPYGIFGALNVNARNFS
VELDRAKEKMENGCMGFLTQPVLTEQAIQNLKQAKAELEGAYILAGLIPVISERNGRFMD
QEINGISVPEEMIESFHGLNREKGEALGRKYVNDIYHEIKEYTDGVYLMTPFQRIGLMEG
IVRDLLQE
>A0A7X4ZJZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MKVMDIFEAKKKEGKPVLSFEIFPPKKEEALKNIDATLEKLCGLHPDFISVTFGAGGSAV
DNQTVEIAKKIKNTYGVEPIVHLTCLHYEKEEIKVILNQLQESGIENVLALRGDENPNVP
MKQDFKYASELVAYIKGQGDFHISGACYPETHLEAPDAITDIRNLKKKVDAGATHLVSQL
FFDNEMFYRFYEKTRIAGIDVPVEAGIMPVTNKAQIERMVNICGASLPKKFEKILHKYEN
NKEALFDAGLAYAINQIVDLIANDVDGIHIFTMNNPKVAGRICDGIRNLI
>A0A7C8HP55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacteraceae bacterium|TrEMBL
MTAVQKTQPVQAVFDAAAARLGRVGGPRVSFEFFPPKSDKLEEQLWAVIRRLEPLAPSFV
SVTYGAGGSTRDRTHRTVSRIVEETSLTPAAHLTCVAASRGEVDDVMRAYWDAGVRHIVA
LRGDPQGGAGAAYEPHPDGYAYAADLVAGARKIAPFEVSVAVYADKHPDSATWQTEIDNF
KRKIDAGATRGISNFFVDADSFLRLRDRLADAGITAPIVPGVMPVSNFNGFKRMAAVGGV
YVPDWFAAIFEGLDDDPETRLLVAAATTGELCARLAAEGVEDFHFYTLNRAELTLAICRM
LGVKAQKEVAQ
>A0A6I0F8M0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus safensis|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYSIEEIKR
SFREQLYILLNEEPDGLLLETYYDIEEAKAVLQIARKETTLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPLLENSHLSVYPNSSLPSLEAGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHISAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAVKKRSIIVELDPPKKLNFEKFLVAANELKDAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMAKAGEDKEKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKESNVHVNYH
>A0A8J6MWT9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfacyla euxinica|TrEMBL
MENDLKSGSNLEKTLRAGHFAFTGELGPPRGTSADEVRKKAAYLKGMVDSVNITDNQTAV
VRMASWAACLILIQEGLEPNFQMVCRDRNRLALQADILGVYAHGIRNMLCLSGDHQKFGD
HPDARGVFDLDSMQLINLVKKMRDEGQFLSGGELQEPPKMFIGAAANPFAEPYEWRVHRL
AKKINAGADFVQTQCIYNMDRFKDFMKKAVDMGLHEKCHILAGVTPMKSVGMARYMATQV
PGMDVP
>A0A3C0TFX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium|TrEMBL
MIKERFHTNRPTYSIEVFPPKKDTDVSVIYDALDEFKYLQPDFISVTYGAGGNTVENTFA
IANYIQNQCRIEALCHLTCAAIPDPLFLKNFLTNIYKNGVKNLLPLRGDQPKGMSDEVFN
SRYYKHASDLVREVKDSYDFCVAGACYPEVHPEAKSADEDLKNLKLKVEQGVDFLTTQLF
YDNEIFFKFMERVRGAGIGVPVLAGLMPVTSYRQIDNIIRLSGTAIPKAFMDDLEKYKDN
DRDVKKCSIDFIKRQMEELLNHGVNGIHLYSMNKVEIAKSVFD
>A0A165P1M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. HI0054|TrEMBL
MTTPAVSFEVFPPRTVGAAFKLWDAAQALAPLAPRFFSVTYGAGGTTRDLTHDSAHVLHR
TSGLPVAGHLTCVGASRAETLDVADKFAEAGIKDIVALRGDPQAGTDKFVPHPEGFADSC
ELIEALAKTGKFTIRVGAYPDPHPEAADQQANIDWLKRKFDAGADEALTQFFFEAETFLR
FRDACVKAGIDKPITPGILPVVNWTSARKFAVKCGTPVPEWVDQAYEAAIRDDRHDLLAQ
AMCTELCSELIDEGVDALHFYTLNRAELTRDVCRAIGVTPQVDLSDVA
>A0A0D2FKY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhinocladiella mackenziei CBS 650.93|TrEMBL
MHISKKLALAHENKKPTFSFEFFPPKTAQGVQNLYDRMDRMHELGPAFIDITWGAGGRHS
QLTCEMVNAAQTHYGLETCMHLTCTDMERSQVDEALRYAYKAGCTNILALRGDPPRDQEK
WEAKDEGFRFAKDLIKYIKSQYGDHFDIGVAGYPEGCDDNRDVDLLIEHLKEKVDAGASF
VITQMFYDVDIFLNWVQKCRDRGINVPIIPGIMPISTHAAFLRRANWTKCHIPPEWHEAL
EPVKNDDAAVRDIGKDLVAQMCRKIVDAGILHLHFYTMNLAQATKMVLEELSMTPATSGM
PLEKPLPWRQSLGFNRRDETVRPIFWRNRNTSYITRTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANIKLWGKPKTLREVTALFVRFLEGNLDRLPWSEGAISTEADSIKADLL
KLNRNGLLTINSQPAIDGAPSTHPVYGWGPAGGWVYQKAYLELLVFPSIFSTVMERLDAN
KNLTYYAVNQKGELYTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WSKCYPAGSGSRKLIETIMDECYLVNIVNNDFHQTHEIFKVFEGLQAQDLDKVFEDTDID
DHRNATRDVVKGDTRATEVEKKIASGNQQAVPFQANGVVLSN
>A0A258RTF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. 28-63-12|TrEMBL
MLARLFDDASLEMTAKDIEQIDAMAARVPAGTMVSVTFLPGESFASRIDAAAAVHRRGLK
PVPHLSARRLTSAGELEGFLDALAERIELRQVFVVAGDLAEPAGPYHDALAVIRSGLLEK
YGVRHVGIAGYPQGHPGIDNARLWRALADKDAELTTRGLDYSIMTQFGFDAVPILDWLAQ
LRATGIDKTVRVGVAGPASVKALLRFAARCGVGASAKVMQKYGLSLTKLLGAAGPDPILD
ELAAGLDRHQHGDVSLHFYPFGGLTRTADWIAAYRAAHRV
>A0A1L3JM88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum todarodis|TrEMBL
MKITEHIKNANRKTLFSFEIIPPKKGNNIQDLYNNIDPLMEFKPPFIDVTTSREEYVYLD
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFSKEETEYVLVDCHYLGIEN
VMALRGDAMSHQKYFEPSKNGNHYAKDLVEQIQNLNCGKYLHDVIEANHKSDFCIGVAGY
PEKHLEAPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFQFVEAAKKAGINVPIIPGIK
PLAVKRHLQLLPQVFKIDLPEDLINEVELCKTNKDVREVGVEWAIQQSKELLEAGAPVLH
YYSMGKSDNIHKIASSIF
>A0A2W7NTY5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cupriavidus alkaliphilus|TrEMBL
MQDRYFSFEFFPPKTAEGTEKLRNTRAQLAPLKPKYISVTFGAGGTTQQGTLDAVLEIQR
EGIEAAPHLSCVGSSRESIRAILQQYRDGGIRHIVALRGDMPSGMGEIGEFRYANELVEF
IRAETGDWFNIEVAAYPEYHPQAKSPRHDLDNFVRKVRAGADSAITQYFYNADAYFRFVD
DVRALGVEVPIVPGIMPITNYSQLMRFSEMCGAEVPRWVAKRLESFGDDRESIRAFGLDV
VTALCERLLAAGVPGLHFYTLNAAGATKAIWQRLKL
>A0A2A5YTE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonadaceae bacterium MED-G03|TrEMBL
MTFPDRLPPLYADLAGDARVSFEFFPPKTEKMEAQLWSAIETLAPLAPRFVSVTYGAGGS
TRERTHNTVARIARETPLAAAAHLTCVAASKGEIDEIADSYWAAGVRHIVALRGDPPEQG
GRFEAHPDGYTGAADLVAGLVKRHPFEISVSAYPEVHPDARDAQSDLDNLKRKLDAGATR
AITQFFFAPDTYFRFMDRVRGAGIDADIVPGIMPVGNFASVQRMAAMCNTDVPAWMGRLF
EGLDDRPAARQLVSATIAAELCRKLYEGGVRDFHFYTLNRAEHSYAICHLLGLRPKVMAN
AAA
>A0A8C3IEK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chrysemys picta bellii|TrEMBL
MVNEPPSASNGSASSRSDGSSSGSEGSKDSSRCSTPVLDAERHERLREKMRRRYDSGDKW
FSLEFFPPRTANGAVNLISRFDRMGMGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETVLHMTCCNQTKEEITGHLQKAKHLGLKNIMALRGDPIGEEWEEEVEGFNYAVDLV
KHIRCEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVSAGADFIITQLFFRSKTFLTF
MKDCQAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKEVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVSGLHFYTLNREVATTEILKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIHRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELMSEESVFEVFTCYISGEPNKEGHKVTCLPWNDDPLAAETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSENITALLKVLKTKKYELRVN
YHIVNVRGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEEESPSRMIIQYIHDNYYLVNLVDNEFPLENCLWQVMEDTFELLNCPTEQ
>A0A7Y5EG50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. CM27|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
NEVKVPAAPHLSCVGDSKADLRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQETADHFHLEVAAYPEMHPQARNFEADLGNFVHKVKAGANSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRM
>A0A6M1S2E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas sp|TrEMBL
MSSQEHPLGISFEFFPPNTDAGREKLIHVRDELAACNPRFFSVTYGAGGSTQARTRDIVR
TVSESGITTAPHLSCIGSEKAQLRDLLAQYQAEGVDSLVALRGDMPSGMGSIGELRYANE
LVEFIRAETGDHFDIAVAAYPESHPQAPSLDKDVENFARKMNAGANMAITQYFFTADAYF
HFVDKARALGVEQPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAF
GTEVVTRLCERLLNGGAPGLHFYTLNQAAPVMKIVDNLT
>A0A2A4YTE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKIIDKINKELKSDKIFYSFEYFPPKTETGKQNLYFKLEKMGKLEPLFIDVTWGAGGSTS
DLTMEICSNTQNILSLESQMHLTCTNIDEDVLKQTLETAKENNIRNILALRGDPSIGSDH
WEASDQNFKYAIDLVKYIRKNYGDYFGISVAGYPEGHPQGDYKSDLNFLKQKVDAGADFV
ITQLFYDVDLFLKFHDDCRAIGINCPILPGILPIVNYDNFKKLTEFCKIKIPEYILADLE
PIKNDDKKVAEYGIQLSIKMCQKLIDNNINYLHLYTLNRESSCVKIIEGLDLTKDLHEKR
AFPWKPRIGSDENVRPIFWNNTIEYYLQRTSDWEKFPNGRWGSIHESQYGEIQDYHLFSI
SLGSVENKRAMWGEVKSLTDVAQVFIDFLNFNIKYIPWCDNLANETSVINNKLVELNKKG
YFTINSQPNVNGMPSNHPDGWGGSNGYLYQKAYLELFASKDRLDDILSGIDTERFSYCAV
NKKGDIITNCEGATIAVTWGIFPNTEIIQPTIVDYESFLIWKEDAFNLWLTEWATIYDKK
SPSHKLIQEIHDNFYLVFFVDNHYIDGDIFDLF
>A0A353VFT2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKIIEHLASANGKTLFSFEVLPPLKGENIESLYNIIDPLMEFKPPFIDVTYHREEYVFKD
RGNGLLEKRSIRKRPGTVGICAAIMYRYKVDAVPHIICGGFNREETENALVDLDYLGIDN
VLVLRGDPIRSEIYFKPEPDGHAYAIDLVKQVDAMNHGIYLEESIGDTHPTDFCIGIAGY
PEKHFEAPNMKSDLHWLRKKVESGAEYLVTQMFYDNSKYFEFVKQVREAGIEVPIIPGLK
PIATKKHLNLLPHRFNIDLPDDLVNEVNQCEDNKAVREVGIEWCIHQSRELMDAGVPVLH
YYTMGKSDNVYRIARELF
>A0A1Z9K7H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium TMED175|TrEMBL
MQKSSTITSALNQESPLFSVEFFPPKDDAGGRRMLETAEAIRPYSPNFVSITYGAGGGTR
ETTMRYARILQDEYNFEVMPHLTCVGHTVDELLEILEDFAKAGFRNVMALRGDPXQGEDV
FKAXAGGLSYGSDLVEXIRKHFPDFGIGVGGYPEKHPEAXXXTIDXXXLKTKVDAGADFI
TTQLFFDNRVXFDFVKSXXEAGIDKPILPGLLPVLSLGQVRRFCXMCEASLPAALEQSLT
QAEDEDHPVIGSEWAAAQIXELLNGGAPGYHIYALNKPQXTLQILESLGIEKTAA
>A0A2D5KG86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MQVIERLRNTKKTLFSFEILPPLKGKSIQSIYDGIDPLLEFDPAFVNVTYHREEFIYKKR
EKGYLEKIAIKKRPGTVGICAAIKNKYNIEAVPHLICGGFTREETENALIDLNFLGIDNV
LALRGDPIKTEPHFIPENGGNKYAVDLVRQIVDLNQGKYIDENIENATPTNFSIGVAGYP
EKHFESPNMQADIRRLKEKIDAGAHYVVTQLFFDNKKFFAFVKACRDAGIDVPIIPGIKP
IESLRHITFLPKFFNIDLPSELTDQLEQCTSNEETREVGTKWAIQQSKELVEFGVPCIHY
YTMGKSKTVRRIAQAVFKK
>A0A0B5KPK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermotoga sp. RQ7|TrEMBL
MRKSLESGKCVVLEVLTPRGTNLKKFLDFTEKAWETGIDAFTVTDMPMGRVRMAPWAVSH
LLVESGKEVLMHFTRNTRNMIRIQSDLLGCHALGIENLLLLSGDDPSHGDYPQTTSVNDV
DILDLIRLTKLLNEGTDLAGNRMYGKTNFFVGGALNPFSEKDLERAKQKIEAGVDFLVTQ
PLFQKDVAQKIKEKLSTKILVSIAFFENAKQMNHFSGVPGIEIPKEIIESAEKGDEHVKE
RSFEAVLRFVEETRNIVDGFYIVAVVKDLEKIRMVVEVAKG
>A0A258NZL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaromonas sp. 35-63-35|TrEMBL
MNLPISFEFFPPKTPEGADKLRLTRRALYAHQPEFCSVTFGAGGSTQEGTFGTVGEILKE
GVDAACHFSCVGATKATVRQQLAALQAMGVKRLVALRGDLPSGYGAGGEFHYASDLVAFI
REFTGNAFHIEVAAYPEIHPQAKSADADLQAFAAKVKAGANSAITQYFFNADAYFRFVED
TRRLGVDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASIRSFGLDVI
TDLCDQLQTAGAPGIHFYTMNQAAATTEIIRRLQPV
>A0A2N3CVN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium HGW-Alphaproteobacteria-17|TrEMBL
MTSNLNSLAEARRAAASPLFANLDGDIGVSFEFFPPKTEKMEAQLWDTFRALEPLAPRFV
SVTYGAGGSTRERTHATVARIAAESAVAPAAHLTCVEASRAEINEVAEAYWAAGVRHIVA
LRGDMPGGAPYRAHPDGYANAVELVAGLKGIAPFDISVAAYPEVHPDADCPQADLDNLKR
KLDAGANRAITQFFFAPDSFLRFRDAAAAAGIDAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMVSLFDGLDDLPGARQLVAATVAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPVSPAKDQAA
>A0A2N5RKE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira pilosicoli SP16|TrEMBL
MNNNVENFIKKLENNNEYCFTLEISPQAKYDLSYIEEKINNSQIQNYADAFVVTDSPFAN
IKISPILASIQLQQKLNNNKPFIATQTMRDKNSIALQNDLIGANYFDIRMILAVTGDAIA
NGNQKQAKGVFEGNSNLLIDIIKNLNKSKSLGEFTFKEPLKPIYPFCVINSYAKNDDSLK
VRLAKKANSGVKAIFTQPIYEVERLEFLLKCIDELPLKEKPILVPGFFPVLTYKTAYFIY
YKLSGSYIPEKWLSKLKKASDKSEEEERKTAIELSSKLFEDMLKIHKKMHIMSLNNYEFV
VDLLKNI
>A0A1Y4RXC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium sp. An14|TrEMBL
MKIRDILGQGRPTISFEVFPPKTAENYESVKAAALEIARLKPAFMSVTYGAGGGTSQYTV
DIASALKEQGGVTALAHLTCVSSTREKVHQVLGELKARGIENVLALRGDIPADGRVAEDY
RYASELIREIREFGDFCIGAACYPEGHVESDRKTDDIRHLKEKVEAGCDFVTTQMFFDNN
ILYNFLYRIREQGISVPVAAGIMPVTNKSQIKRICQMSGTELPARFKALLDRFGDDPAAM
KQAGIAYATEQIIDLIANGVDAIHVYSMNKPEVAARIRENLSDIIK
>A0A2E1ZFM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriales bacterium|TrEMBL
MKVTEHIKKAKKTLFSFEILPPLKGTSIQSIYDSLDPLVEFSPPFIDVTYHREEYVYKKR
NDGLLQRKSVRKRPGTVGICAAIMNKYDIDTVPHIICGGFNQEETENALIDLSFLGIDNV
LVLRGDPIKHETYFKAEEGGHSYASELLQQVVAMNKGIYLDEELKNSSPTNFCVGVAGYP
EKHFESPNMRSDIHFLKKKVEAGADYIVTQMFFDNQQYFDFVDLCRENDITIPIIPGLKP
ISTMKQLRLLPQRFNLSVPNPLVDIVIKCKNNEQVRQVGVEWAIQQTKELIEFGAPCIHF
YTMGKSDNVQEIVGNFS
>A0A1S7MPG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium fabacearum S56|TrEMBL
MHDISTSPAIAASIEASPAQVLGPASLAGIFPQGVRVYLTDTGQASQDRLVDAAKHLRDL
GYTPVPHLAARRISSGVEFEEQVKRLAGEAGVSDVLVVGGGVATPAGPFASSIDMLSTGI
FDRCGINQIAIAGHPEGSPDFSEETATAALKLKYDFAERSDAAMRIVTQFGFDPARFIAW
AEGLAASGIDLPVHIGVSGPARITTLLKYAALCGVGNSIAYLKKNALSLTTLAKGHSPES
VVGPIERHWQANPAGPIRQIHVFPFGGLQNSADWLAGRGSWQIGDADFSAKRGTVAI
>A0A1F9XC29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium RIFOXYB2_FULL_48_7|TrEMBL
MKLKELFDKGKFVITSEVGPPKGWQIDKTIHEAESLRNVVDAINVTDNQSSVMRFGSLAC
CHLIKDRGIEPVFQVTCRDRNRLALQSDILSAAALGIENMLLLTGDHTTLGDHKDAKPVF
DLDSVSLAHAVKKLESGVDLAGNKLDGEPPKFCIGAVVSPCAEPLEPQLIKMEHKIKAGV
QFFQTQAVYEVDKFAKFMEKAKQWGIPVMAGIVILKTAGMAKFMNENVAGIHVPDNLIEE
LKKDKEKTKSGQTGIEIAARLIKDLCPLCQGIHLMPLGWDDKVPKILELSGVASITGQK
>A0A7H4PUY2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia sp|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAQLAPLKPKFVSCTFGAGGSTQQGTLDTVLDIAK
DGIEAAPHLSCIGSSRESLRAILNEYRSHGIRHIVALRGDLPSGMGAVGELRYASELVAF
IRAETGDWFNIEVAAYPEYHPQSRSPSADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSDMCGAEVPRWVARRLESFGDDRESIRAFGLDV
VTDLCRRLVDANVPGLHFYTLNGAAATRSICERLGAR
>A0A5N6YAT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus arachidicola|TrEMBL
MHISQKLAQNDSVGKIGVSFEFFPPKTAQGVQNLYGRMDRMHGLGPSFIDITWGAGGRQS
DLTCEMVGVAQSMYGLETCMHLTCTDMPRQRVDQALEAAYQAGCTNILALRGEPPRDQRN
WEAADNGFRYAKDLVKYIREKYGNYFDIGVGGYPEGADDNSDVDLLIDHLKEKVDAGSTF
IITQMFYNADGFVEWVRKCRVKGINVPIIPGIMPIQSYATFIRRANWTKTLVPPEWRQAL
EPVQNDDAAVRNIGKRLLADMCRKLLASGITHLHFYTMNLAQSTKLVLEELGLVPSNENP
IRKSLPWRGECPVERGVGGPPYDKNLNLSVHTPSGLGKRRALR
>J9BQ42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus HuA2-1|TrEMBL
MKLLDLLSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRATLNVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKDAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7H2WKP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter seifertii|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVKHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIDKVLHFSGKARDIQDFEQFLEQAQTANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKAFLTKNNYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLADEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYVEQYRHLELKALEELWNSLWQVT
SSKEFSPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGLGRFIFKASFWDNTLVAK
VLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDHCEFGDRECI
HSVKARLAKVVKQTEVLKEKLIPTVSIETRGTSSWKNWYLGVEA
>E0U104|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus spizizenii (strain ATCC 23059 / NRRL B-14472 / W23)|TrEMBL
MGLLEDLQKQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETSLPIMLNVSMHEQGVLQDGTP
LSEALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITDKEVKTRPKEFIS
VQDERTEPGLNEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPVYIGIMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIYLH
>A0A1B9AHV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. FJAT-27986|TrEMBL
MKLLETLNEKILVADGASGTLLYSFGIDSCFEELNLTNPNQIKKMHRSYIEAGADVIQSN
TFGANFHKLKRYGLEREVSQINRAGMKIAKDAADPNTFIIGTIGGLRSFRKSELTLTEIK
GYFDEQLTALLEEKPDGILLETYYDLDELLTVIESARKMSDLPLIANISLHETGLLQNGM
HVSEAFSLMKKTGADVLGINCRMGPYHMIRSYEEVPLLEDTYYAAYPNASLPDLSDGRYV
YSTEADYFINSSRQLVKQGVRLLGGCCGTTPAHIQAIRKGIEDLHPVKVKDFVAKPKHQP
ISYEIIQYKRKGPDTISGKAKKQTTVIVELDPPKTFGLEDFLIGSRYLLDSGADAITLAD
NSLASPRISNLAVASILQSKLNTVPLVHLTCRDHNLIGLQSHLMGMHSLGLSEVLVVTGD
PSKIGDFPGATSVYDLSSMDLISLVKQLNEGRSYSGKSLGSRANFDIAAAFNPNVKYIDK
AVQRMEKKIQAGADYFLTQPVFSIEKLEEVYAATRHITKPIFIGIMPLTSHRNAEFLHNE
VPGISLPVHVREAMERAGTDKEACARESFAISKELVDAASELFNGIYIITPFMKYELSGH
LVRYIKEQKSVVNKEVHLS
>A0A1Q6G0B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides sp. 41_26|TrEMBL
MKVIDLIHSNEKTAFSFEILPPLKGTGIEKLCRDIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNKLRRRPGTVAVAAAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYYHAIELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDSDIYWLKKKVEAGAEYAVTQLFYDNQKYFDFVEKARQEDINIPIIPGIKP
FKKTSQLSMIPKTFKVDLPDDLVKEALKCKNEAEVQQVGVEWCVKQCRELMAHGVSSIHF
YSIGAVDSIKEVAKEIY
>A0A4P9K7E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiomicrorhabdus sediminis|TrEMBL
MKSQQKYEQKFSLEFFPPRTEKGSEKLKTVVEELGTLNPEYMSVTYGAGGTTQERTLETV
RYIQQNTNFDAAPHLTCIGASEESVTELLDTYEAMGIKRIVALRGDLPSGMMDPGEFKYA
SDLIRFIKDTRGDTFKLEVAAYPETHPQARNCEVGIKWFKHKVDQGADSAITQYFFNVDS
YLYFIDNCERHNIDIPIVPGIMPITNYENLIRFSEGCGAEVPRWLKCRLESFEDDLASLQ
DFGKEVVMDLSQRLLDAGAPGVHFYSMNSTEPTLEIVKSLSFK
>K9GDB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium digitatum (strain PHI26 / CECT 20796)|TrEMBL
MHIREKLAKNEAEGKTGISFEFFPPKTAQGVQNLYDRMDRMHGLGPSFIDITWGAGGRLS
DLTCEMVSVAQSVYGLETCMHLTCTDMPLEKVDQALQAAYKAGCTNILALRGDPPRDKET
WEAAENGFCYAKDLVKYIRNKYGNHFDIGVGGYPEGADDNADVDQLIDHLKEKVDAGSSF
VVTQMFYDADNFIEWVKKCRAKGITVPIIPGIMPIQTYASFIRRSSWTKVHVPPQWMEAL
EPVKNDDSAVREIGKTLIANMCRQLIAAGIKHLHFYTMNLAQATQLVLKELDLSPSEESP
IQRALPWRPSLGLGRRTEDVRPVFWRNRNSSYVARTQTWDEYPNGRWTDSRSPAFGELDA
YGVGLKGTNEQNIKLWGEPKSVKDISDIFVDFLTGKLDRLPWSDSPITTEAHEIQEDLLK
LNQRGFLTINSQPAVNGVKSSHPVYGWGPKNGFVYQKAYLELLVPSSLIDELITRIEKND
DLTYHATNKKGELKTNTRDSPNALTWGIFAGREIIQPTIVETVSFLAWKDEAYLLGEHWS
KCYDAASPSRKLIQQVMDDWYLVNIVDNDFHRSNAVFELFNGLEIKGLNVEVDGKPLTNG
HAEQNGVAAN
>A0A560XB95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. T12|TrEMBL
MALGTASTRTDRARTVRDMLAAGKTTYSFEFWAPKTEKGERNLWNALRRVEAVAPSFVSV
TYGAGGSTRAGTVKATEQIAADTTLTPVAHLTAVDHSVAQLRNIIGQYADAGIRNMLAVR
GDPPGDPMADWVPHPEGLTYAAELVELIKESGDFCVGVAAFPEMHPRSADWNTDVAHFVD
KCRAGADYAITQMFFRPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPQLSNAAF
PDALKERILTAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQA
>A0A5M6IZ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodovastum atsumiense|TrEMBL
MNDTPAPLERWLTGPRFSALPARDGSQPAPALSFEFFPPRTEALEQQLWACIRRLEPLAP
RFVSVTYGAGGSTQERTHATVARIVRETSLTPAAHLTCVGASRGEVDDVARAYWDAGIRH
IVALRGDVPGGGAYQPHPQGYAYAADLVAGLKRIADFEISVAAYPEMHPAAASPQADLDN
LRRKLDAGANRAITQYFFEAETYLRFIDRCLAAGITAPIVPGIMPVSNFAQAVKFSAMCG
ARVPAWLGHLFAGLEEDAETRRMVAVVVAAELVRLLQANGVDEFHFYTLNRPDLVYAIAH
ILGAHARPAAG
>A0A4R0NNS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter psychroterrae|TrEMBL
MKIVDHIKNAQGKTLFSFELLPPIKGQSIQGIFNAIDPLMEFNPPFIDVTYLREDYIYKQ
HANGLLEKVAYRKRPSTVATCAAIMNKYRVDAVPHLICGGFTKDETENALIDLQFLGIDN
VLVLRGDARKSDSSFIPTPNGHAYASELLQHVADMNKGKYLHDDMESPEKTDFCIGVAGY
PEKHFESPNLDTDFKYLKHKVDCGADFIVTQMFFDNKKYKEFVDKCRQNGINVPIIPGLK
PITSSKQLISLPKIFHLDIPLELSEAVQACKSEKEVKEVGIEWMINQCKELKEMGAPVLH
FYTMGNPEPTKRIAQAIF
>A0A117T376|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria rhizophila|TrEMBL
MPVTPPTARAEDRPQLVAAPRAADQSAPAPGGHPAAAATPAAPAAGTTSSEPPAGTSWLV
RRPRRSTLVSFEVFPPRPTADPDTVWRSIDAMAQAGPDFFSVTHGHSGGRGVSREALRHL
RRTTRTPVMAHFTCGGTDRSGLERSVEQLLDDGVRDLLALRGDPPLGAGQWQTPPGGIGR
ASELVRLIRDVERRRFGDGFRPGTRPLSVSVACYPSPARGRDPEADLASLWEKQEAGADY
AITQVLYEPEDYASFLERARSEGIHIPVVAGLMPLTNPKRLQRMTEITGVPVPERLTRFL
TADSPEELRHRGTATTLLLIDDLLDLGCAGFHLYTFNRPDAALTILEHLRVRDAAREYRG
RSPAA
>A0A8H7LGV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MKLSEKLANHTSDAPYFTFEFFPPRTEQGYSNLLTRITGLASLKPIAASVTWGAGGSTRD
RSLDLAAFCQAENGLDTILHLTCTNMEKGTIDEALTTAMEKGVSTILALRGDPPRGEEYW
IPTDPRFQHAEDLVTYIKQHPKFGNHFCIGVAGYPDGHSEGGSEEEQLTHLKRKVGAGAE
FIITQLFYDVEKFKSWLRKVRSTGITVPVIPGMMPLQTYATFTRMTDLCKATVPQHIQAN
LDAIKHDDQLVKEYGASLAVSMIRSILVDGDVKGVHFCTLNLEKSVRKILDELGWTHGTH
HPNQIITDASQSPHILPAPADAPHPVTFTISPSEATQHAATSLAEHTRTGTLRTAAEAIN
SGWDDFPNGRFGDSKSPAFGVVDPWDGGGLGVPPHVAISQWGRPTTEQDLADLFLAYLNH
KAPTTPFSPTPLSDESITILPHLISLTSKGLWTVASQPAVDGILSSDPVVGWGPKDGRVF
QKSFVEFFATEEELVKVAKAIEDSGDGWVTFFAGNNDDGFLSNIPDSGSNAVTWGVFPGQ
EIAQPTIIDRDSFLAWKASIYTWTMREIAIEYMEQDDAFMIWHDFGLCYSPDSPTRKLLE
NVTKTRWLVSIVHHDYKDPNALWDFLAKHLN
>A0A8H3BGC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizoctonia solani|TrEMBL
MPPFTRSVAKARLRDVSTPPRTYADRVLTQMQRDSLWDSQAPPRKFSDARGLKDLIEIAV
VFVVATVLDITKDIVMISKKPIGWVLATYLVLMALSGTSELFVRTFMSPVCSLPLISSRI
EYCNRDELSRRFSPDFPKLVSLQSRLEDVMDDSASSSIVAVDIKNSEMAVRDLTTLVKIS
TLVAKDSLVERLNEFVVDAKTAGRNLQRFGGRVGGAVDQIVAMNEYVLKLLENTAKDSQA
QISSGPVQRVMNAVSPIKVSGPQVIAARRKEVETMWYQATGMMDATIRKLIHEAEANIIA
LDKLESQLDLINEMILREDEGIRAKAEEVLGELWTKLGGNKKKLNSFRSHRMLLNEIRTY
RKRALAHVSSTLVQLQGLSADLDDLRQRVVTPTLAGEEAGIPLEVHIGSMQKGTERLLEG
RKRAREREDAYLQKGLQNLLDRIERMRGLGPEFIDITWNAGGRTSDLTSELVKTCQGVIG
IETCMHLTCTNMPQEKVDVALREAKANGCRNILALRGDPPSGQEEWTTVEGGFQHGIDLV
KHIRREHDDYFDIAVAGFPQTIQLPEAEAKQEMQWLKEKCDAGANFIFTQMFYDADMFIR
WVKAARDAGITVPIVPGINPIQTWNGFIRATTLSGTDIPQDLMDILEPHKNNDEKVRELG
TKIVSDLCRKILDAGIGIKGLHFYTMNLEKGTKMLLEELNLVPRVETIKPLPWRQSLTPT
RRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELDGYGIWIKQTPEEGRK
IWGTPTTIGDVKALFTKFCTQQIKALPWSDQPPTTEMLVIGQQLARMNELGYLTINSQPA
VNGARSDDKAFGWGPKNGYVYQKAYLEFFVHPSQLHALIKRIERDTNVTYYAINKQGDLK
TNSTSEGPTAVTWGVFPGKEVIQPTIVEAVSFMAWKDEAFELGCQWAKIYEPESPSRKLI
ENMMDEYFLVNFVHNDFHDREAIFRPFFADAGLQTNGDTETPAVNGVKHVNGLVNGHSTA
VRA
>A0A0C9MLB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor ambiguus|TrEMBL
MKVVDKITKAENEGRTYWSFEYFPPKTEMGVQNLYDRMERMQRFGPEFVDVTWGAGGTSA
DLTMDIVATSQSVYGLETMMHLTCTNMPVESIDTALKAAKACGCQNILALRGDPPKGQLN
WESCENGFNHAVDLVRYIRKNYGDYFCIAVAGHPEGHIDNEDKEDDLLRLKEKVDAGADL
IVTQLFFDVDVFVQFVKRCRDIGITCPILPGIFPIQSYAGLKRVISFNNNAVPQKLWDDL
ESIKDDDQAVKDYGIDLAVEYVHQIKQQTGINGFHIYTFNLERSSRLILEKLGLVPEQEH
VKPLPWNPSLGPKRTKETVRPIFWKNRAQSYIQRTESWDEFPNGRWGDARSPAFGEFDRW
GVSIKYPIEKRLAMWGEPQSPDDIALLFAKYCKGRLEGLPWSAQKLEPETDTIKQRLAAI
NLLGYLTINSQPAVNGAKSNHPVYGWGPKNGYVYQKAYIEFFIPPSKLDELVQKIGTDPE
VTYFAVNKNGDLRTNTVDEEPNAVTWGVFPGKEIVQPTIVEPTAFMAWKDEAFGLWNEWA
RTYDRQSLAAEVILDIYENWYLVNIVHNDFQDENGIWRLFDLEIDGDLSKKLRRGSGSL
>A0A0C9MSA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor ambiguus|TrEMBL
MKVIDKIHKAEQEGRPFWSFEYFPPKTPQGVQNLYDRMERMQRYGPEFIDVTWGAGGTSA
DLTTEIVATAQSVYGLETMMHLTCTNMPVKQIDDALEAAKNCGCQNILALRGDPPKGQAN
WESCKEGFEHADDLVRYIREKYDDYFCIAVAGHPEGHIDNPDKEDDLLQLKKKVDAGADL
VVTQLFFDIDSFLTFYKKARAIGITVPILPGVFPIQNYTGLKRVISFNNNFVPQKIWDDL
EPIKDDDTAVKEYGINLTVEFIQKFREIGVNGFHIYTFNLERSSRIVLERLNLMAPVESI
KPLPWNPSLTSKRAKENVRPIFWKNRAKSYIQRTETWDEFPNGRWGDSRSPAFGELDGWG
INLKYPVEQCLEMWGSPTSIDDVAQTFARYCKGQIAGIPWSAQQLDAETDIIRQRLAAIN
LLGYLSINSQPAVNGVKSSHSVYGWGPKNGYVFQKAYLEFFVSPEKLDELIEKVGKDPQV
TYYAVNKQGDLRTNTQSDEPNAVTWGVFPGKEIVQPTIVEAVAFMAWKDEAFELWSRWAR
IYERESESAELILDITKNWYLINIVHNDFQDENGIWRLFDLEIDGEISRKLLQSNTVAR
>A0A0C9MHV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor ambiguus|TrEMBL
MNIIDKIEQAQKSNHIAYSFEYFPPKTELGFANLIDRLGRMAQLEPEFISCTWGAGGSTH
DRTLELCTTAQSLYGLDTLMHLTCTNMEKAKIDEALEQAQKAGIRNILALRGDPPRGHEY
WTPVDSEFQHAIDLVKYIRKHYGDTFCIGVAGYPEGHIDCPDKEQDMQYLKEKVDAGADF
VMTQLFYDVDACVTWMQKCRAYGIQVPIVPGIMPIPTYQSFRRMINLCNVKVPDNIMSDL
DAIKGDDQKVKEYGVNLAVKMIQRLHKEAGICNFHISTLNLERSTRLILEALHLHKENGL
HVNKVSPWAPIHDPAKAELWDEFPNGRYGDSRSPAYGENTYSSGQILPTSQAILKWGEPE
TEQDIAQLFINYINGQVKSLPWCEEALHTESETIRQRLTDINQRGYWTVSSQPAVNGASS
QDKIYGWGPKNGYVYQKAFIEFFVSDQQVAELLIRLGKDDSITYYATNQKGDFSTNVSDA
EAQNAVTWGVFPGKEIIQPTIIEKASFEAWKDEAFGLWTEWEEQYAPNSPSQKVLKEIGD
SYWLVNVVHNDFQKPDVLFDVMLS
>W1YCU0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|human gut metagenome|TrEMBL
QSAVFLSIRRFLALRGDPPRGVAAEDVVGELRHADQLVRVIREVEAEYFDDGARHVQVAV
AAYPAAVDYA
>W1XIT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|human gut metagenome|TrEMBL
YMMTLREKHQQGQFTITVELDPPKSSSAEKTFEQAARLKGKVDAINIADSPMSKMRMSPI
SLSYLLQHNKEIETIFHLTCRDRNIIGL
>A0A1S2T7J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polynucleobacter sp. QLW-P1DATA-2|TrEMBL
MELSVEFFPPKTPEGENKLHLVRERFSETLKPSFYSVTFGAGGSTQSGTLKVVSDIHAAG
AAVAPHLSCVGSSRESVREMLKQYQALGVKRIVALRGDLPSGMGQYGEFHHANELVEFIR
TETGDWFHIDVAAYPETHPQAKSPASDVDFFVQKMKAGANSAVTQYFYNTDAYFRFVDEA
YDLGVTQPVIAGIMPITNSTQLLRFSDACGAEIPRWIRLRLQSYGDDIASIRAFGEEVVT
DLCDQLLTAGAPGLHFYSLNQADAVLAIADNLDLTN
>A0A0F6ARM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella abortus (strain S19)|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>A0A1C6SAP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora inyonensis|TrEMBL
MSRPRGPTTLVRMSVPPPFSPVDGPATPTSSPGTGPSLRHVLAGATRGLLLFGITPPRAS
ATNEQAREIARLTLARLDPLDVDALVLYDIDDESDRNPDERPFPYLPTMDPAVFHAAHLA
GWRRPAIVYRCVGKYPEPELRDWLRAVDTDRVGGVFVGASSGSKQVHTTLPRAHALRRET
RPDLAVGGVAIPERHTRGLDEHLRMLTKQERGCGFFVSQVIYDVDASKSMVSDYHYACRD
RGVTPRPVVFTLSVCGSLRTLAFLQWLGVRVPRWLENALRHADDPLAESYEQCLATAREL
VTFCRRLGMPFGFNVESVSNRKLEIDASVALAARVRDLLGRPSA
>A0A1E3G2H3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fervidobacterium thailandense|TrEMBL
MKIVDKISRQKVLSVEIIPPKKGGDVDEIFKTLDKLMEFDISFVNITRHPVEVEYVEFGD
RIEKVYKMKRPGTVGLTAAILRRYGDEIEVVPHLICKGMNKFEMENLLIDLWIMGVENVF
VVRGEETKTPQKGDYTYSYELVEQIAKMNEGKYLYMEIPERKTDFCIGVAGYPEKHFESP
NLDEDISFLKRKIDAGAHFVITQMVFDANVYADFVERCRRVGVDVPILPGVKPVVSLKSV
YAIPKKFFVNIPQSFLERMKDARTESEEFEIGVSFTVELINELLEKGAPGVHLFTMGRGK
ETCEVLKRLGRFS
>A0A1B9LIZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella apicola|TrEMBL
MKTNQLFNKKTVFSFEVFPPKKSSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHAVKHTYGIESVAHLPGINFDKAEIKKILTDLKCAGIDNVLALRGDISPNVKPKDDF
RFASELVTFIKENGDFNIIGACYPEGHLEAPTLKQDLIHLKEKVNAGTDQLISQLFFDND
YFYTFLDKAHDMGIHVPIEAGIMPVTNKNQIERMVTMCGVNLPKKFKQMMQKYEYHPEAF
RDAGIAYAIDQIVDLISQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKVQ
>K9RXQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. (strain ATCC 27167 / PCC 6312)|TrEMBL
MSITPPSRLQQAIQRGEFLITAEVCPPKGSDPQHMMDNAHRLKHRVHGINITDGSRAVMR
MSSLVAAILLKQAGLEPIYQVACRDRNRIALQADLLGAAACGVQNILALTGDPIQAGDHP
QARPVFDLESVRLLQLIGKLNQGLDSNDKPLPDQPTQLFPGAAIDPQSPSWSGLQQRFER
KLTAGAQFFQSQLITDFDRLDKFMNQIALGCGKPILAGIFLLKSAKNAQFINRAVPGVQI
PDHVIERLAQAPEPLQEGIKIAAEQVQQAQHLCQGVHLMAVRREDLIPQILDLANIPPVA
>R7KY36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. CAG:353|TrEMBL
MRISELFGKGKCVFSFEVFPPKKNMPCDTIYSTLDSLKKLDPAFISVTYGAGGSDGNNIT
GKIAAHIKNDLGIESAAHLTCVSNTKQDIDIILEGLKADGIENILALRGDINPERPPKND
FRYASDLIRYIKSKGDFHISAACYPECHVEAPDMITDIKYLKEKVDAGAEHLMSQLFFDN
SHFYSFLEKARIAGINVPIEAGIMPVVNKKQIERMVSMCGASLPVKFTRMMARYENNPEA
LRDAGIAYAIDQIVDLISSGADGIHLYTMNNPYVAEKISSAVSGLL
>A0A195B9Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Atta colombica|TrEMBL
MRNLILENDICERNDADGNDNPSISDFHIENPHKTIVNLRQLLNDKISKNEIFYSFEIVS
TRKSGVFYRRFLIDMEEYSPLFYALTWHNEATSNNDGYLPLDLAENFPANTLLHLAAKDS
LSENGDFEHAADLVVFIRQRFGDTFCVCVAGYPQMHPESPSKELDLHYLKAKVEAGADFI
ITQICFDSRVLINFVRDCREIGIQIPILPGILIPTNHACLEKMIDKCRLDVPIKIKEELA
RMKDDDQAVRKYSVDLIAQIITDVIRNGATYGFHLFTLNRLSLVTEICKHIESFKAEKL
>A0A4W5K746|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hucho hucho|TrEMBL
MFSPVCERLSECENFSVNTWRTCSKSDSSGASNSGGESSKESSRSSTPVLDTDRTDRLRD
KMRRRTESGDHWFSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKET
SSMMIASTAVNYCGLESILHLTCCNQTKEKITGYLSKAKRLGLKNIMALRGDPMGADWEE
EEAGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRHLKEKVDAGADFIIT
QLFFRADTFLKFVRDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEIMRVIEPI
KDNDAAIRNYGIEQAVGMCRVLLESGEVPGLHFYTLNREVATMEVLRQLGLWIEDPRRTL
PWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFY
LKSKSSKDALLKMWGEELTSEQSVYEVFTSYITAQPNVAGHKVMCLPWNDDPLAPETNLL
KDELDKVNRRGVLTINSQPSINGKPSSDPIVGWGPPGGYVFQKAYLEFFTSSENVTALLK
VLKKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPTVVDPVSFLYWKDEA
FALWIEQWANLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLWQVIDDMFELLDNPP
EEQPAEQPNDEQSDKEQPGK
>A0A844Z9L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontixanthobacter aestiaquae|TrEMBL
MNPTLNQMHEARTALDSPLFEGLAGDIDVSFEFFPPKTDKMGETLWQSVETLKPLGPRFA
SVTYGAGGSTRARTHEQVARIQNEAGIPAAAHLTCVAATRDEVNEVARHYWEEGIRHIVA
LRGDAPDGSGTYAPHPGGYANAVELIAGLKEIADFEISVAAYPEVHPDSPDAQADIDNLK
AKFDAGATRAITQFFFDPQCFFEFRDQAAAAGIKGEIVPGIMPVVSFAAVQRMSGLCGTA
IPTWMEGLFDGLDERPAARQLVSATITAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GMRPKDNGQ
>A0A7Y3FXA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
SILAGMTPMKSAGMAKYMKNRVPGMDVPDEIVKRLADTPKEKQAEEGINICVEAIQRIKE
MKGIKGFHVMAIEWEEKVPEIVERAGLHPRPDLN
>A0A7C7QM90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MGKTFKEALASGKFVITANISSPKGVNVDSLINQVKFLKDLTDGLVVPDNLLATMTMSAC
AASRLVIENGVDPIMSLNCRDRNRIALASDLLGASLMDIKNILCVSGDHTKFGDHIDAKP
VYDIDSVQLLGMARGLEKGRDISHNELNGYPQFCLGAVANPEADPLGPQLNKFDKKVQAG
AEFFLTLPVFNIDNLKRFMEHARKSEVKILASIRVLVPEEVHKYADGSYPGLFVPEDVLE
EIKDASIDKGIEVAGRLIRDIKDRNICDGINLMASGYEERIPDILKAGGI
>A0A7C7QHR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKSESKLEKILNAGHFAVTGECGPPRGADPEAIRKKAKYLKGMVDMVNVTDNQTAVVRMS
SWAGCLILIQEGLEPNYQMVCRDRNRLAMQSDILGAYSLGIKNILCLSGDHQRFGDHPGA
KNVYDIDSMNLINMVKTMRDEGRFLSGAEITVPPKMFIGAAANPFGDPFEFRVHRLAKKV
AAGADFIQTQCIYNMDKFKKWMAQARDMGLTEKVYILAGVTPMKSLGMARYMKNMVPGMD
VPDEIIKRLRGVDKKRQADEGIRICVEQIQELREIDGVAGIHLMAIEWEQRVPEIVESAG
LLPRPEV
>A0A0P0P0M8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter henricii|TrEMBL
MTLPPARRVIGPVARAGERGQSQAGGRPRVSFEFFPPKTPAMEESLWQAITRLAPLDPAF
VSVTYGAGGSTRERTHRTVKRILDETHLKPAAHLTCVGASRDEVDEVIREYWQTGVRHIV
SLRGDPPPTEGGIGGVYVPRADGYANATELTQAVRGIAPFEVLVGVYPEKHPESPSIQHD
IEVLKAKVDAGATLAISQFFFDIDAFLRFVDQVRAAGITIPILPGIMPVTNFNGLKKMSV
ACQTAVPTWLANLFEGLDNDADTRRLIACSVAAEMCAKLQEQGFEDFHFYTLNRADLVYA
ICRVLGVRERETAGSEVAA
>A0A1Q3DS01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium glutamicum|TrEMBL
MSLTNIPASSQWAISDVLKRPSPGRVPFSVEFMPPRDDAAEERLYRAAEVFHDLGASFVS
VTYGAGGSTRERTSRIARRLAKQPLTTLVHLTLVNHTREEMKAILREYLELGLTNLLALR
GDPPGDPLGDWVSTDGGLNYASELIDLIKSTPEFREFDLGIASFPEGHFRAKTLEEDTKY
TLAKLRGGAEYSITQMFFDVEDYLRLRDRLVAADPIHGAKPIIPGIMPITSLRSVRRQVE
LSGAQLPSQLEESLVRAANGNEEANKDEIRKVGIEYSTNIAERLIAEGAEDLHFMTLNFT
RATQEVLYNLGMAPAWGAERGQDAVR
>A0A0W1EX01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. H038|TrEMBL
MTSNLNSLAEARRAAASPLFANLEGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASRAEIDEVAHAYWDAGVRHIVA
LRGDVPGGAPYRAHPDGYANAIELVAGLKAIAPFDISVAAYPETHPDADCPQSDLDNLKR
KLDAGATRAITQFFFSPDSFLRFRDAAAAAGITAPIIPGILPVSNVSQTRRMADMCGTAI
PAWMISLFEGLDDLPAARQLVAATIAAEMCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPAVAPATEKAA
>A0A351B1Z2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium|TrEMBL
MKTDSTLEKILASGKLAVTSECGPPRGALPEKVREKANLLKGYVDAVNVTDNQTAMVRMS
SLSACILLKQLGLNPILQMVTRDRNRLAMQSDILGAYAHGIDNMLCLSGDHTSFGDHPMA
ACVHDIDSIQLINMVKNMRDEGKFQGGEKIDGPPKMFIGAAANPFADPFELRVARLAKKV
KAGVEFIQTQCIFNLDKFEKWMEGVRDRGLDEKVYILAGITPMKSVGMAKYMKNKVPGMD
VPDDVVKRMAGVPKEKQAEEGIKICVESIQRLKEVKGVKGFHIMAIEWEQKVPEIVEKAG
LLPRP
>I3B7M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum 35B|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A660NJ55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lautropia sp|TrEMBL
MTRQAPSLSFEFFPPTTDAGAQKLLETHRALQALQPEYFSVTFGAGGSTQARTAEAVTNL
TAAGSEVAPHLTCVGATRDSIRELLDGYRAQGVKRLVALRGDLPSGTMSLGDFQHATDLV
RFVREHSGDWFTIEVAAYPEMHPQATSPDTDLAHFAEKVAAGADSAITQYFYNADAYFNF
VERARAAGVTIPIVPGIMPILNYTQLSRFSDNCGAEIPRWIRLRLAAFHDDMDSLRAFGH
DVVVDLCDRLLAGGAPGIHFYTMNQAGPCAAIWQALKR
>A0A435KHU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.13.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETGIPAAAHLTCVGATRDEVDAVIRDYKSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKTIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFKQVANFSARAGAHVPGWLAERFE
GLDKDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAAAA
GSAAA
>A0A0Q3WQT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacillus choshinensis|TrEMBL
MTTSKRNLREYLQDHLLIGDGAMATQLHRLGVPVGVSFEELCLSNPKLVQEVHNSYYDAG
ARLLETNTYSANRDSLSRYGMEHKVARINRLAVKIARESAKDDAYVAGSIGSILAGRVRK
KVLDEYRDQYEEQAIALLHAGVDGIILETFLDLEELLLALEVIRPLTDAPLIAQLATLEV
GRTRDGYSLSEAFGQLKTAGADIIGLNCRLGPAEILRSFENALVPEGALLSAFPNAGRLG
LTDGEYAFKSTPDYFAMSALRLREQGIRLLGGCCGTTPAHVKAMADALEDLEPQARINPT
IPSGDRPHISVTNVREQGKPSIVERVKTEKTVIVEFDPPRDLDADAFLDGCCELHRAGAD
AITLADNSLATVRMSNMALGALMKSRHGIDPLLHIACRDRNLIGQQSHLMGLHALGIDQI
LVITGDPSRFGDLPGATSVFDVTSFDLIRMVKQLNEGVSFAGRPLKQKAQFIVGAAFNPN
VRQIDAAIARLEKKVEAGADYIMTQPVYDAESIKLVYEATKHIGIPVFIGIMPLTSSRNA
EFLHNEVPGIKLSAEALDRMKKVQGEAARQEGIKMAKELLDTAIQYFNGIYLITPFNYSS
MAAELVQYVRQQSALVKTASSTH
>A0A6N3X424|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Synechococcus spongiarum 142|TrEMBL
MKSQVSPSAFQEALASGQPVITAEISPPRGGSVQHVLATADQLRDRVHALNVTDGSRAVM
GMSSVAVCRLLLERNLEPVLQLGCRDRNRIALQADLLGAHALGLRNVLCLTGDPVKVGDQ
PKARPVFDYEAVRLLQDVKNLNQGLDALERPLPDGPTALFPGCAADPQSPSWSGLRSRLQ
RKKEAGARFIQTQMVTDPDALRRFCRELAAPLGFPVLAGVFLLKSGKNARFINRMVPGAS
IPDEAIARLDGARTPWMEGLQMAAEQVAAYLEIAQGVHIMAIKAESAIPQILDLAGVPPL
APPIPGGLGLRSLAAEPC
>A0A824L8U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEIFPPRRDENIKNLNAILDDLGQLSPNFISVTFGAGGSINSKNTLETASLIQEE
YKIPSIVHLPCIHSSKEKITSILQECKERQLDKILALRGDVCNDLEKSKDFSYASDLISF
IRKQGEFEIYAACYPEKHNESRNFIEDIHHLKNKVDAGTDKLITQLFYNNEDFYTFKQNC
ALAGINIPIYAGIMPITNKRQVLKISQLCGAKIPPKFAKILEKYENNTLALEDAGIAYAI
DQIVDLITSGVDGIHLYTMNKSKAAIKIYEAVKYLLKEELHA
>A0A698BXI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter jejuni|TrEMBL
MCSFSFEVFPPRKDENIKNLHAILDDLGQLSPNFISVTFGAGGSINSQNTLEVASLIQEE
YQIPSIVHLPCIHSSKEKITQILQKCKEKNLNQILALRGDICENLKK
>A0A139C9S6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonadaceae bacterium T82-2|TrEMBL
MSAHEHPLGISFEFFPPNTDAGREKLMAARDALAERKPRFFSVTYGAGGSTQARTHETVQ
RVRDGGISTAPHLSCIGSEKAQVRELLERYRADGIDSLVALRGDLPSGMGGVGELRYANE
LVEFIRAETGDHFEIAVAAYPEAHPQAPSLEHDLQNFARKMQAGADLAITQYFFSAEAYF
HFAERARALGVDKPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSESIQAF
GEEVVSRLCQRLLDGGAPGLHFYTLNQATPALRILDNLA
>A0A1M5JSP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fibrobacter sp. UWCM|TrEMBL
MKIIDILKQDKMSLSFEVFPPKKETSFENVKAATESIAALGPAFMSVTYGAGGGVSHFTL
DIAKNLKEKFNIPMLAHLTCVSSSKETVHQRIDDMKAAGIKNVMALRGDLTPELIEKGRD
NCDYHYAVELIRELKAADADFCIGAACYPEKHPESANQAEDIKHLKEKVDAGADFLTTQM
VFDNNLFFSFLYKLRDAGVNCPVLPGIMPITNANQVERAIKLSGSFMPQRFKSLVDKFGS
DPEAMKQAGIIYASDQIIDLYANGITNVHVYSMNKPDVAEGILKNVSAILGKSF
>A0A4P8GTG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. 24S4-2|TrEMBL
MSPPSLIDTHPNLSDAAPVALSYELFPPRSPAAAESLWTTIGELESTDPDYVSVTYGASG
SNRDTAVELINRLLLETTLRPLAHLTCVGNTPQELSEIIGELLDVGVRGILALRGDQPKD
GAAPVAGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPTEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLITRARRAGVTIPIIPGVMPLTSVRRLTRLGELTGVE
PAPDLMARLAAADTDSERRLIGVRATVDLANAALDAGAPGIHLYTFNEHACALEVLDKLA
LPRPARPASRLNAIARRHQEMAS
>A0A212QCS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoblastus acidophilus|TrEMBL
MDTTRPSRERHKPCEISFEFFPPKTDEMEASLWEAIGRLAPLKPKFVSVTYGAGGSTRER
THATVARIVRETSIAPAAHLTCVGATREEVDEVAHAYWEAGVRHIVALRGDPQGGVGGAY
HATPGGYAHSTDLVAGLKNLHDFEITVSAYCEKHPESASYDQDLDVLKRKIDAGATRAIT
QFFFDNDIYFRFLDKARKAGIDIPIVPGVTAVQNFKQTANFAKKAGASVPDWLAERFEGL
DDDPATRRLIAAAVAAEQVFDLLDRGVEQFHFYTMNRADLVFAVCHLLGVRAG
>A0A413TGK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Collinsella sp. AM42-18AC|TrEMBL
MRVDEVFKQAASQGTAPVSFEMFPPKGELTLDTAREVAGNLCKLSPSFVSVTCSAGGSGN
GATTAPIAHMITSEFDTPSVAHLTCVGRTHADIAAKIDEYRSAGVENILALRGDLPAGAT
EDDKPASDYAYARDLIPELIDAGFCVGAAAYPEGHIACEDLNLSVEYLKQKQDAGASFFV
TQLFFDNECFYRFRELADKAGITVPITAGIMPFMGKSQISRMVFMCGASLPSPVIKILAK
YENDPESLQAAGVDYAARQLCDLKEHGAAGLHLYTMNRPAIAATIMERLG
>A0A1Y5FZS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium 47_12_T64|TrEMBL
MKRPDISFELFPPTTANGFDNLGRAVERLKGFDPKYYSVTYGAGGSGQQKSNELISKLSE
DSDLTLAAHITLAGASRQEIRDTVKSWQERGIKRLVALRGDGAVPGEAFVPHPDGFQDSV
ELIAALRELGDFEIAVAAYPDPHPDSRSLADDLEFLKRKQDAGATTAITQFFFEADSYFS
FVDAARKAGITIPIIPGILPINNIAQIKRFADRCGATIPDWVSKAFEGLEDSAETSAAVA
VSLCLDLCRELIEGGVDAFHFYTLNRSPLTEAVCRLLALQTEQKEAA
>A0A2H6FGC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium BMS3Abin08|TrEMBL
MQISEILNTRDRGISFEFFPPKTGEGMSALMKVAVELAEYDPLYVSVTYGAGGSTQDRTR
KLLIKLKEETDLTVMSHLTCIGATGEMMDSLLRDYRDNGIDNILALRGDPPQDAEDYDPA
TGEFRYAKDLVEFVGKYNYFSIGVAVYPEGHQEAPSLEADIEYTKMKVDAGADFAITQMF
FDNRYFFDFLERARKKGINIPILPGIMPITDLVRIKKFSSFCRTTIPSRIEEMMSGVLDK
PEEMRKIGTELAIRQCKELLDSGVKYLHFYTMNKSEVVSEIIRALRV
>A0A0D2CSS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cladophialophora immunda|TrEMBL
MHISKKLELAHQQNKPTFSFEFFPPKTAQGVQNLYDRMDRMHNLGPTFIDITWGAGGRHS
QLTSEMVNATQNYYGLETCMHLTCTDMERQQVDEALRRAYKAGCTNILALRGDPPRDQEK
WEAKEGGFRYAKDLVKYIKARYSDHFDIGVAGYPEGCDDQRDVDLLIDHLKEKVDAGASF
IITQMFYDVDIFLNWVKKCRDRGISVPILPGIMPVQTYAAFVRRANWTKCHVPPEWFEAL
EPVKNDDAAVRAIGKDLVADMCRKILDSGIQHLHFYTMNLAQATRMVLEELSLTPETSGM
PLEKPLPWRQSLGFNRRDETVRPIFWRNRNASYISRTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANIKLWGKPKSLRDVTGLFVRFLQGDLDRLPWSEGAISAEADVIKNDLL
QLNKHGFLTINSQPAVDGASSTHPVYGWGPAGGWVYQKAYLELLVFPSMFKMVMERLNAD
KNLTYYAVNRKGELYTNTKDEGPNAVTWGIFPNREIVQPTVVETVSFLAWKDEAFRLGQD
WAKCYPAGSGSRKLIEKIMDECYLVNIVNNDFHQNKEIFKVFEGLETKDLDLVIEDTVAS
HPESGTKDAVNGDSSLADVEKGLTNGEQHKIPSKASGEVLSN
>S8E8Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fomitopsis pinicola (strain FP-58527)|TrEMBL
MKISQKIALAEKEDRIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
DLTSELVKTCQKLIGVETCMHLTCTNMPKEKVDSALKEAKAHGCRNILALRGDPPAGKDE
WEAVEGGFTHGVDLVRHIRAHYGDYFDIAIAGFPQHVQLPPDELAAELGYLKEKVDAGAQ
LIFTQMFYDVEIFIAWVKAVRAAGIAVPIVPGIAPIQTWNGFIKSTSLSRTEIPPSLLAA
LEPHKNNDEKVRELGTKLVAEMCRRILAEPLGIKGLHFYTMNLERGTRMLLEELSLVPRV
QTVKPLPWRQSLTPNRRTETIRPIFWANRTKSYLSRTENWDEYPNGRFGDSRSPAYGELD
GYGIWIKQKKEEALQLWDHPANVADLGKLFAKFCLGQLAALPWSDQAPSSETSVIATQLA
KLNEMGFLTINSQPAVDGARSDDRIHGWGPPNGYVYQKAYLEFFVSPALLDALLPHIERD
VNITYYVINKRGDLRTNTHSDGPNAVTWGVFPNKEIVQPTIVEAISFMAWKDEAYELGRQ
WAKYYEPGSPTRALIDDVMDTYSLVNVVHNDYKRPDAIFEPFFKAGAEFAVAQGAAPRVL
NGH
>A0A6M2BBI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rahnella contaminans|TrEMBL
MSFFHANQREALNQNLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSSLKPKFLSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRQIAKDYWESGIRHIVALRGD
LPAGGGKPDMYATDLVHLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCAGQGIDVEIVPGILPVSNFKQLTRFATMTNVRVPNWMNSQFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPDIAVPV
RA
>A0A6N4RMJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oenococcus sicerae|TrEMBL
MQLAELFKQKTVFSLEVFPPKKIFSNDWILQSLEDLASVQPDYISVTLGAGGQNFQRDET
VRISDLIQNQLGITAVAHVPGIYKSKQNVLHLLDQLESDHVENILALRGDRLTGKKEVGD
FKHANELISFIKKNRPHFSVAAACYPDCHSEATSFVDDITNLKRKVDAGTDHLITQLFFD
NDSFYSFKEKVEIAGIHVPIEAGIMPCTNKKQIERITEITGVPLPLKFRAIMDRYEDNKI
AMRDAGIAFAIDQIVDLVAHHVDGIHLYTMNNAAIAQRIWQATASLFAESKSRLQH
>A0A8C3G8I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyclopterus lumpus|TrEMBL
MVNQVQRGDGSLRSCKSDSSGLSNSGGESSKESSRCSTPVLEADRSDRLRDKMRRRTESG
DRWFSLEFFPPRTASGAVNLISRFDRMSAGGPLFIDITWHPAGDPGSDKETSSMMIASTA
INYCGLESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEEGFNYAT
DLVKHIRSEFEDYFDICVAGYPTGHPEAESYEEDLRHLKEKVDAGADFIITQLFFRADTF
LKFLDDCRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEIPEEITRVIEPIKDNDAAIRN
YGVQQAVEMCRVLLDSGKVPGLHFYTLNREVAIMEVLRQLGLWIEDPRRSLPWAVSAHPK
RKVEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSTKDA
LLQMWGAELMNEESVYEVFTCYITAQPNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNK
RGVLTINSQPNINGKPSADPIAGWGPAGGYVFQKAYLEFFTSSENVTALLEVLKKYEPRV
NYHIVNVHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVVDPDSFMYWKECSAAFALKTDW
LLSSLKCYVSILLKPGPASDTASSNGPYET
>W7TUD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nannochloropsis gaditana|TrEMBL
MSALATTKPVEAMEDDRIGELLEQRKGHPTPWFSFEFFPPKTPEGVEKLYERLAEMAPYN
PLFVDFTWGAGGSTAELTLELTIEARRRFGLIANMHLTCTNMPTEKVVDALKSAKDAGIT
NILALRGDPPVGQERWEPIEGGFSSALDLVAYIRKHHDTFFSVGVAGYPEGHPNRIQQVD
SLEGLSKAELGRVAVERAEDGTVTGYYVCRDNDFVQEIDYLKAKVDAGADFVITQMFFDA
EVYVAFVKTCRSAGITVPILPGIMCFNTLQGFKRMVAFCRTRVPEKLWMDMMALSKSDDD
EVRRYGIDFGVRLGQELLRAGSSGLHFYCLNLSRVALGIVSGLGLGSQSVDATYTNEKVE
SEIEKAMNGSDKVKSKEKALSNHDHVGAVASS
>A0A1F0QTA4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC078C09|TrEMBL
MSPRLSASAPLDQISEDTPKRPQRTALSFEVIPPRHDADAKKIDRLLDTLAAYNPDYIAV
TSSQRSGWLEGTAAFIEKISRDTAMRPLAHLACTAGTEEELVGWIDTLVDAGVRGLLALR
GDLPEGGMPEGHLPHADSLVRLIRRWESARVARLAAGRLAVGVACYPNGHAESATADEDI
DVLLAKQRLGADFAITQLFFDAEDYVRFAQRARLAGVRIPLIPGIMPMTSRARVERMCQL
SGLDGPPHVLDQLAAATSPEEEKEIGMQLTASLAKSVMNAGADGLHIYTHNNPDITTDLL
HRIGVTP
>A0A1E8Q3D9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium grossiae|TrEMBL
MDFGPCGGVRPDGQCEMRPGPCAFHDVVAWTGPPATPRETVAPLVLTDFSCAPFDRRDVA
ATAAVLGTSCDAVLVGEHQNKPDFPPTLMGALLLDAGVRPFITLSCRDRNRVVLEQELRG
LGSIGVDTVFCVTGDGRGYDVRPDVTQTFDLDGPRLVALAASLGVTAAVPETPTAPPVAA
RPLRLVEKQRAGASLAVLNHVPYPETIAAFMATARAAGLSIPVVAAVAVYTDDVSAAVLQ
GLPGLELDQDVLRQVLGAADPVAAGIDAAVAEARALLAIDGVVGVNVSGLASAAGPRVGA
EIKATVGHRVRQEAQQRSVRQEAQQRSVRREAR
>C0DWJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eikenella corrodens ATCC 23834|TrEMBL
MLHNTLSFEFFPTRTPEGREKQKITRKQLSQYQPEFFSCTSGAGGTTREGTMQTIRDILA
EGMAAAPHIPCVGLDAGELTDLLQEYKDLGIRHVVALRGDIPSGMGLGTTGLHHANELVE
LIRHRFGDWFHIEVAAYPEYHPQSRSAEDDIQSFVRKVKAGADSAITQFFFNADAYFRFL
DDVRGRGVEIPIVPGIMPIANFSKLARFADMCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCGRLLRHGAPGLHFYTLNQAGLSSTICQRLGY
>S0DTJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831)|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAIYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIQGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLSSDNSDHVNGSTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLSGIKDDYWLVNVIHHD
FVERDALWQLLLS
>A0A355L7E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
MKIKDIINNKKVTVSFEVFPPKQWDKIANTKKIVEEMVKDKPSFMSVTYGAAGTTSGFTT
EIANAIKEGGVEPLSHLTCLTSTKEKIDSVLDELEANGIENVLALRGDIPKDFEMGENQY
FHHAFELVNEIKARGKFCVGAACYPETHPESVNRVEDIARLKEKVDCGVDFITTQMFFDN
DKFYNFREMCAIKEINVPIIAGIMPITNANQIKRSLELSNASLPPKFNKIMERFGENPDA
MKQAGIVYATEQIIDLMANGVNNIHIYTMNKPDVAHQIMEGLSAIINE
>S0DPH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831)|TrEMBL
MHIKDMLNDAERSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNLGPKFIDITWGAGGRIA
ELTCEMVLQAQAVYGLETCMHLTCTDMGVEKVNDALLKAYKAGCTNILALRGDPPRAQDK
WTAADGGFQYARDLVKHIRDTYGNHFDIGVAGYPEGSDDNKNEDELLDHLKEKVDMGASF
IVTQMFYDADNFIRWVKRVRERGITIPILPGIMPIATYASFLRRANHMQAKIPQEWLDAL
EPVKNDDVAVRNIGKTLVANMCRKLLANGIHHLHFYTMNLAQATRMLLEELQWAPCAERP
LQQALPWKQSKGLGRREEDVRPIFWRNRNKSYVIRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPKTIHDIALLFVRYLQNEIESLPWSEAPLTTEADEIRDELIE
LNKRGLLTVNSQPAVNGVKSSHPVHGWGPDNGYVYQKSYLELLVHPDVFDKMISRIENHP
DLTYYAVTKDGELRSNVTSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGVDW
AHCYDMSSPSRALLEGVMNDWYLVNIVNNDFHDNKTIFELLKGLEVKGLTTPATPLTESV
GNGAVDTEPIANGTAATAVAN
>A0A1Y2GZF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lobosporangium transversale|TrEMBL
MKIIDRIKKGQEEGRMPFSFEYFSPKTAQGMVNLHDRIERMCHLGPEFIDITWGAGGSRP
AATLEVVSNAQKVYGVETCMHLICTNNPTDKIDKALKEARACGNQNILALRGDPPHGQSE
WSACEGGLAYAADLVRYIRKTHGDYFGIGVAGYPEKHAESPSMEADLLHLKEKVDAGADF
IVTQLFFDVPMFFEWVKKCRAIGITCPIIPGIMPIQAYASFKKNIVGVHVPQWILDGVEP
IKNDDQAIRAFGVEVGIKMTRELIDGGACGIHYYTFNLERSTRLILEGAGLVNKTVYIKK
NMPWRSSFDEKRKEESVRPIFWSNRTKSYISRTDNWDEFPNGRWGDSRSPAYGDLDRYGV
YLKYTAEEAHQHWGSPEKLEDIYKLFVKFCCGEILTLPWSDQALALESGTIKDRLVELNS
CGYLTINSQPAVNGAKSDDKIVGWGPKGGYVYQKAYLEFFVSPEILEKLKMRLSKSPQFT
YMAINKTGDLHTNTNGSKPNAVTWGVFPGREVVQPTIVELSSFDAWKDEAFALWEQWSRC
YPQNSKSHELLNNINQTWYLVNIVNNDYHEKDGIFELFKEDILKLQAQQTIVADGDVNGI
DVRTGASGANMDQITAKFKETTVVSPEVEPLIVEQPLRV
>A0A349DC37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oscillospiraceae bacterium|TrEMBL
AGIAYATDQIIDLYANGITHVHVYSMNKPDVAAQIKNNLSDILGKDA
>A0A4S9MEI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEVAAPEAPQ
KVNGATNGEKHEEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A3S4T9Y8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces howellii|TrEMBL
MTRTHPGTATCRPSLSLELFPPRPGPHASQTWGALGRLLRARPDFVSVTYRPRFVTTAGG
PRGQAAGSGSGPRPTRVHVIEERNPSEDVVAHVLETSEVPLMAHMTCIGYRKRDAVGIVR
RFLDMGVRRFLALRGDPPAGVQPDDVVGELPRAEDLVRVIREVEAEYFDDGARHLQVAVA
AYPADVDHGLGVEVLAAKQAAGADLAISQVFYEAEDYLALTRSCLYSGVDMPILPGIIPL
TDLRRLTRLESLTGVRVPTDLRAALSSQGAGRAGSAGTGPVTRGIDATLRLATEVLEGGA
PGLHLYTFNRTRPALDVISQLRLGGILSGSVPSRQAQHEVNRDYLNASPGGDRRAHPGPP
GAGWSCPSPGPPAPERGAGP
>A0A4S9GWF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aureobasidium pullulans|TrEMBL
MHISAKLQAAAKEKKATYSFEFFPPKTAQGVQNLYDRMDRMHNFGPSFIDITWGAGGRHA
SLTCEMVKVAQTVYGLETCMHLTCTDMPKSKIDDALKEAHDAGCTNILALRGDPPREKEK
WEATSGGFRYAKDLVKYIKETYGDHFDIGVAGYPEGCDDNDNPEELIQHLKEKVDLGGTF
IVTQMFYDADIFLDWVKKVRAAGIDVPIVPGIMPISTHAAFLRRANWSNIHVPPHWHEAL
EPVKNDDAAVRDVGTGLVVELCRKLMDNGIQHLHFYTMNLAQSTRMILEELSITPSQDTP
LEKPLPWRQSLGLNRRDENVRPIFWRNRNRSYIARTQDWDEFPNGRWGDSRSPAYGELDT
YGIGLKGTNEQNRKLWGEPKSFGDVATLFANYMQGKVESLPWSESPITDEADALRKDLIN
LNQRGLLTINSQPPVDGAKSSHPVYGWGPRNGYVYQKAYLEVLVSPELISELITRMERNP
NITYFAVNQHGDLKTNSPDEGPNAVTWGVFPGKEIVQPTIVETVSFLAWRDEFYRLGSDW
SRCYDATSPSRYVIDDLMQNWYLVNIVNNDFREQRGIFPLFDELEVPDLNKEITAPEAPQ
KVNGVTNGEKHEEEPKVGNGDVTDSKIPDSVHKKLETQINGAEEKPDTEPKDATAHNTGA
GPSTSV
>A0A067C8D2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprolegnia parasitica (strain CBS 223.65)|TrEMBL
MLLLSWQLRVFLGATSLVLLYDLVVLIALGSSYMLPFLPGAVSLSCAGASLVVGILSLVY
VVRASKLATLTPLAWLSLLHVALLTAIAVTAFMCAHDPDLVTELTLEDQSFLWRVGLRGA
YYPTTDTFDWTPPSDVNCSSMDGKNVTLKQRFDEAYCAKRGHVYCDSFPMRARYPSNCER
GEKHNVFDVPMTNSSTLTNFCDQVTPSVLTAEPTLSALCDGCQRMHETSAFSDWIDDNCV
RNARVDGLSTFCIFYRSPKIYPELSPACRYAMMKPRYDTSFADVCYHTTFPAKIQRDAKA
LAASAVALGAMSLVVAFFSGLEMLMHLACTNMSRGSIKNALDAAKDAGIQNILARQDDL
>A0A844GKP3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blautia luti DSM 14534|TrEMBL
MKLSEAMKEKMLLSFEVFPPKTEKGMENLPGTIEHLMKYKPEYISCTYGAGGGNVGANRE
VCQMIKKAGTTPVTHFTVIKNTKEGIKDQLQQYLDEGVDHMLALRGDIPLGETTTCGDFN
YATDLVKFVRNEFGDKFEIAVAGSPEGHIACRSLDADIAVLKQKQDNGADYIMTQLCWDM
EQFKYWLDAIREAGVTMPVDVGVMPILDMSATINMALSRNGCVMDSELCRLISRNWLFPN
PFAAKDADGKPFDMFYDDKVKRFKEEGIEYTIRQIDEYRAMGVDGIHLYALNKWKDVSEI
IDRSGLRTLV
>A0A8H7W9C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cadophora malorum|TrEMBL
MEKITTKIASLPPGTSYFSLEFFPPKTTMGSSNLRARLDRMSRALRPLFITVTWGAGGST
ATKSLELAELCQRELGLTTCLHLTCTNMSRKLVDRALEDAKALGIRNILALRGDPPRGEE
YRELGADGEDGEDDGQEFEWAVDLVRYIRKQYGDYFCIGVAAYPEGHADESDPAGQSLEH
DLPYLVGKVQAGADFIMTQLFFDVEAYDNFEKRLREHESGAFKDMPIIPGMMPIQSYQMI
KRTTKLSHARMPPDVMDRLDKVRGDDEMVKKVGVDIVSEMVTHIQKEPAPGPRGFHFYTL
NLEKAVAFILERTNLIPSTPLDSESAILDVPSPLESVQINGSSHKRPSRRQSSIGSDPHN
RVIITGSKTSNPDRETTAEEAAIPAEPVNTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAYGEIDGYGVSLHMSVNQAIKLWGFPTSVEDITSLFIRHIEGSISALPWSEEGLNE
ETNTIKSQLLKLNQKGWWTVASQPAVNGVKSSDPIFGWGPKNGFVFQKAFVELFIPENDW
KDLHAKLTSSEIAPMVSWYAANASGSFLSSSPNSSSSENGDGGGSTNAVTWGAFPGKEII
TPTIIEEVSFRAWAEEAFGIWGEWGRVYPTRSVSKGVVDGCREGYWLVNVIHHGYVEREG
LWELLLS
>A0A7T8LIE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella bongori|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7Y2UPW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfofustis sp|TrEMBL
MEATTSTFSPPSHLIAEIDPPKGTNLDTFLDKALKIRGRVARVRVTDNEHAILRMSPLAP
CRALKEKGVEPSMVINGRDRNRLSFQGDLLCAATMGIDDVVLKEGHDPKEGDQPMARTSG
DLDLETMLICASAMNDGKDLAGEELDGGTNFNIGVYIELSDDVNFNRERAEYFLKLKDFG
VQSVTLGPTYDLNIVEQFQPFAEQTGIKLYSSLMFLKSVTMIRYLNNLPGVPSIPQEFLK
KMMGATDKKNAGMEVAADFLKELAPISDGVVLLSLGLHDKMTEFLDLIER
>A0A6G6JZD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseimicrobium sp. ORNL1|TrEMBL
MHIRDIFSERKPTFSFEFFPPKTPEGAETLFEAIRELEVYKPAFVSVTYGAGGTTRDLTH
ELVVRIKQTTSLDPVPHLTCVCHSEADIASILERYAEAGVSNILALGGDPPRNLANYEKA
KDAFQHASDLVRFIRGFAESGAHKDGRGFGVGVAGFPEGHPSTPNRLLEMDYLKAKVDAG
ADYICTQLFFDNRDFFDFRDRCRLAGIHVPILAGIMPISSASGMKRMAELAGGARFPAKL
LKAIARCGNDEDAVQRVGVHYATEQCADLLDHQVDGIHFYTLNKSKATREIYADLGLKDS
HSFQSHPSPA
>A0A6M0KW03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia cyriacigeorgica|TrEMBL
MVSGTPSVVQSLRLHSSRAVPFSVEFNPPRDAAGEARLWRAVRTFERMHPAFVSMTYGAG
GSTKDRTVRVTGELAGETTLLPVAHLTAVGHSVAELRSLVGAYADSGIRNILVLRGDPPG
DPLGEWHRHPEGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLDHDTRFLAAKLRAG
AEYSITQMFFDVEHYLRLRDRLVAMDPIEGAKPIIPELMPITSLRTVKRAEELCGRPLPR
SVIDRLERAAGSGPEEDAAAVRAVGIEIATEMAQRLIDEGAPCLHFITLNFAKATGEVLT
NLGYGVTAAPISA
>A0A6G9FMQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Tu 2975|TrEMBL
MALGTASTRTDRARTVRDMLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVAPNFVSV
TYGAGGSTRAGTVKATQEIAADTTLTPVAHLTAVNHSVAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPEGVSYAADLVRLIKESGDFCVGVAAFPEMHPRSKDWDEDTRHFVD
KCRAGADYAITQMFFVPEDYLRLRDRVSAAGCETPIIPEIMPVTSVKQIERFATLSNAHF
PAELKERILAVKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHEQS
>A0A7L2S9J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mystacornis crossleyi|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A4R7CW69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter caenipelagi|TrEMBL
MKVTDHITNAKGKTLFSFEIVPPVKGRNIQELYNNIDPLMEFNPPFIDVTTSREETIYIA
KEGLLDRRTTRMRPGTVGICASIQHKYNVDTVPHVLCGGFTKEETEYMLVDCHYLGIQNV
MALRGDARSEQKYFEPTDGGHPFAINLVKQIQDLNCGKYLHETIESEYSSEFCIGVAGYP
EKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEAAKNIGITVPIIPGIKP
IAVKRHMQLLPQVFRIDLPQDLIEAIDGCATNKDIRKVGIEWAIQQSKELKDAGVPVLHY
YSMGKSDNIKAIAEALF
>A0A521SBS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Patescibacteria group bacterium|TrEMBL
MFATRLWSSADAPPTFSMEVFPPRPEHAAAFRQTITALASCRPAFFSLTCGNEADRRPAT
LDWAARIQRETDTPVIAHLTCLGQSRDALRREVETLLDAGVANILALRGDMPRTGAPSVG
FRHAAELIAELRTLRLPLCIGAACHPQGHPEAANADADLRHLREKVDAGADFLVTQAIFD
VATFTAFLRRARTAGVGVPVLPGILVPAGAAQIQRFAQRCGVRLPRGLPSWFRIEEAQGG
ELAGLTHAAELAVALPRCGAPGVHLFTMNREEPAQRLHARLRRMTAGTRTPS
>A0A447MCH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella bongori|TrEMBL
MLALNRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPS
WMSLMFEGLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVR
PGL
>I0T1Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis SK575|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKNKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKHIHQATHALFNHQSLG
>A0A2I0FFW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Moritella sp. Urea-trap-13|TrEMBL
MSFHNAQNIEVLNQSVSELGRDINVSFEFFPPNSPAMTSTLWESINRLKTLEPKFVSVTY
GANSGTRDRTHDIIKQIKHETGLIAAPHLTCIDANRQELKQIATDYWDNGIRNIVALRGD
LPPGLNQPDMYAADLVALLKEVNDFDISVAAYPEVHPEAKNAQADLLALKDKIDAGADRA
ISQFFFDTESFLRFRDRCAAVGIDKEIVPGILPVSNYKTLCKFSKLTNVKVPNWMHSQFA
GLDNDQATRNLVGASIAIDQVKVLSREGVKDFHFYTLNRADLTYAICHTLGVRPK
>A0A257M298|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium VVV1|TrEMBL
MHILDILSTRRPSLSFEFFPPRTPAGWEELYQTIRDLEPLEPSFVSVTYGAGGGTRELTH
DLVVRIKQTTAIPPVPHLTCVGHTRAEIDALLERYAAAGVNTILALRGDPPKGETNYDWS
KGDFRRAADLVRFIREFNESGRHPDPRGFGIGVAGFPEGHPDMPNRLLELDYLKAKIDEG
ADYICTQLFFDNHDFLDFRERCDLLGIHVPIIAGIMPVTTTSGMKRMAELAAGARYPAKL
LKALDRANGDAEAVERVGIHYAAQQCSELLDAGVDGIHFYTLNKSPVTREIYASLGLATR
QA
>A0A0J1H708|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium aquae|TrEMBL
MGYSHASHLDSLNQTIADLDGKINVSFEFFPPSSAQMEQTLWQSIHRLKALKPKFVSVTY
GANSGERDRTHSIIKDIKDQTGLVAAPHLTCIDASRDELRAIARDYWQNGIRQIVALRGD
LPPGGGKPDMYASDLVELLRSEADFDISVAAYPEVHPEARSAQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVAAGIEVEIVPGILPVSNMTLAKRFALTNNVKIPGWLEKQYE
GLEDDLLSRQMVGASNAIDMVRVLSREGVKDFHFYTLNRAELTYAICHTLGIRANNVVPA
>A0A1W6NWY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ketogulonicigenium robustum|TrEMBL
MTTAPLLRDFSIEVTPRSLRETPDIAKWLPRGTTVYIAHIAGTPIDDMVHAARRLRDLGF
EPQPHLPARVIPSRAVFDTLLQRYTGEAGVRRALLLGGGPAAPAGPFDSANQLLDGGVFD
RLGFTHLHFAGHPEGSPDLDPNGGTATADSALLTKHAFAQRTDARVALVTQFVFDAQPVI
NWSQRIAAMGIDVPIHVGVAGPAHAAILLRYGLACGIGPSLQVLRKRARDIRRFIWPMKP
DAIVADLARHVAAHPASQIAQLHLFPLGGIKPAAKWAAGHIAQG
>A0A4R1D6V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. BMG5.11|TrEMBL
MNEEIAHSAPLYASLPGDIGVSFEFFPPKTEKMAETLWDSVRTLEPLRPDFVSVTYGAGG
STRERTHAAVQRIIRETAIPAAAHLTCVDATREEVDAIAREYWDSGIRHIVALRGDSSDP
AGGYRPHPGGYENAAALIEGLLKIAPFEISTAAYPETHPDSVDEQVDLDNLKRKLDAGAT
RAITQFFFEPECFFRFRDKAAAAGITAEIIPGIMPILSFASVQRMSGLCGTAIPGWLETL
FRGLDERPAARQLVAATVAAELCRRLYAGDVRQFHFYTLNRAELSYAICHLLGRRPAGEA
A
>A0A3F3Q0E5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus welwitschiae|TrEMBL
MGSAVRHGAFSGGSIGRRKSCSSPPPSFTPSFLAFHSLSSVRHRVAVSAAAETGLIMEKI
TDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGSTAARS
LELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMH
GEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDGQDPARDLPYLIEKT
QAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVTKLSHV
KIPPHVLSKLEEVKHDDDAVKRIGVDIITDLVHGIRDLVSPGLRGFHFYTLNLEKTVSFI
LERCELIPPYTEIDDSDALADGGNLSALDSSSYIAPNGAPIRTLASRRSSVSSIPHNRVI
VDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPWSEGGA
EEDSNGLNAETAIIQPELLTLIDKKGWWTLASQPAINGVRSDDPVFGWGPPGEGFVFQKP
FVEFFCPTKDYLTVLKPLLQKHGHEKLAWFATNAKGDFESSLPGPNTDDPDPIDINPANV
NAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDDTKNDVW
LVCVVGQEFGAGTEPGSEEEEDEKKWMWRELANSQ
>A0A1A7NV94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gallibacterium genomosp. 3|TrEMBL
MSYAKEIDVLNRSIADLNGEINVSFEFFPPKNEKMENLLWDSIQRLKVLQPKFVSVTYGA
NSGERERTHGVVKAIKQQTGIEAAPHLTGIDASPEQLKQIAKEYWESGIRRIVALRGDEP
PGYSKKPFYARDLVELLKGVADFDISVAAYPEVHPEAKSAQADLIFLKQKVEAGANRAIT
QFFFDIDSYLRFRDRCVTVGIDVEIVPGILPVSNFVQLQKMAKVTNVRIPSWMHKLYDGL
EQDQTTRNLIGASIAIDMVKILSKEGVKDFHFYTLNRSELTYAICHTLGLRPHLAAA
>A0A2G2VEE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum baccatum|TrEMBL
MKVIEKIQEAIKNDKVIFSFEFFPPKTEDGVENLFERMERMVTHGPSFCDITWGAGGSTA
DLTLEIVKRMQNMVCVESMMHLTCTNMPVEKIDQALDTIKSDGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGIATKEIYENDLAYLK
KKVDAGADLIITQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTK
IPEEIMAALEPIKDNEEAVKAYGIHLGTEMCKKILANGIKQLHLYTLNMEKSALAILMNL
GFIEETKISRPLPWRRPANVFRVKEDVRPIFWANRPKSYISRTIGWDEYPHGRWSNAQNP
SYGALTDYQFMRARSRDKKLQEEWAVPLNSVEDIYERFKDYCLGKLRSCPWSELEGLQPE
TKIINEKLGHVNTKGFLTINSQPAVNAEKSDSPSVGWGGPGGYVYQKAYLEFFCSQEKLN
ALVEKCKSFPYLTYMAVNKEGNWISNVNQTDVNAVTWGVFPAKEIIQPTVVDPASFMVWK
DEAFEIWSRGWAQLYPEADPSRKVLQQVQNSYFLVSLVDNDYINGDLFSIFKDI
>A0A7X5L169|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium MD335|TrEMBL
MKKQTEHCLTSFLKKDRLITDGSFGTYYADKYQTNDMPELANISQDETIWQRVVKIHEEY
RMAGAMLIRTNTFASNTVLLGADLDAVLENINHAVHFARIAVRNCGNENDCFIAGDIGPI
PLDACYKAEDAEREYYIIGRNFVDAGIDILNFETFPELAQILPAITKLKADARRESRALF
IMVQFSVNQFGYSAGGMSAKRLLAQAAECDAIDAVGLNCGVGPAHMEQIIGGIDQALLRG
KPLIALPNAGYPKRVRDRICFQDQSDYFAYKEAGLCSRFGVDIAGGCCGTTPAYIRLLAQ
QLAQTPKTRKSECAKPQAKTVHVTDNAFFKNKPMGEKLIAVELAPPANADDERVLDAAHF
LSDLGVDVLTFPDSPSGRTRVDSVLMAQKVHRETGMCVMPHICCRDKNAIAMRSVFLGAH
INDIHNFLIITGDPVPTLIRQTTKAVFNFDSVGLMNIVHGMNEENFAQAPLTYGGAINQG
RKNLDAETARVHKKMAAGASFFLTQPVFTEEAAARVRRIKNETGARILCGIMPLINRNNA
LFMKNEIAGVEVSDEIIQRYPEHAGREEGEAVGIEIAVEIIKKTSDFADGYYFEFPFNRV
RMLKQILQKL
>A0A8K0V5Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenebrionibacter intestinalis|TrEMBL
MSFFHANQREALNQNLAEMQGQINVSFEFFPPRTHDMEATLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRTIARDYWENGIRHIVALRGD
LPPGGGKPDMYACDLVALLKEEADFDISVAAYPEVHPQAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNYRQLTKFAAMTNVRVPKWMDNIFE
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPTVCS
>A0A0Q6VLA2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aeromicrobium sp. Root344|TrEMBL
MPSPDQSLVDALRGPSPSYSFEFFPPKDDEGEAVLWQTIADLEEFDPTFVSVTYGAGGTS
QERTVRITARIAEQTRMRPVGHLTLVAQTKGEIESVLKQYAAAGVDNVLALRGDPKGGPR
APWEPHPDGMDHAIDLVGLAKDLGGFCIGVAAFPEGHPDAASIDHDAQVLVDKAEAGAEY
AITQLFFRASDYFALVERVRAKGCDIPIVPGIMPILNFAQVARMAELSGAELPREVLDQV
EPIQDDKAAVRSKGIELATQLCRDLLAGGAPGLHFITLNRSKATREIFEALRADGLV
>D5WUJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kyrpidia tusciae (strain DSM 2912 / NBRC 15312 / T2)|TrEMBL
MYNVHGLREKLALGKFVTTVELEPPKGADPLPTMEAAKFLRGKVDAVNIADSPMATLRMS
PIALAHIVQEDLGLEAIFHLTCRDRNLLGLQSELLGAAALGVRNILTLTGDSPSRGDHPE
VKGVFETDSIGLARLAERLNQGYDLTGHELNGPTRFLIGGVANPGAEDLDAEVAKLAAKV
EVGVRFVQTQPVFDIETALRFWERTRHLPVHILFGLLPLKSARQARYFNEKVPGVRVGED
VIQKVEEGGRAAGIALCRELYGGLREFAAGAHLFPIGDLRAVYEILDIDTDLRRAAM
>A0A1Z9GXD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium TMED156|TrEMBL
MEISIEFFPPKSEEGFARLDAAANELSKLNISYASVTYGAGGSTQNGTLSSVEMLSKVFK
KAVPHISCIGADKDNIINILENYKQLEFDHLIVLRGDLPSGFGRGGEFSNAVDLVKFIRE
KFQDYFRIDVAAYPEIHPQAASPSHDIKYFSDKIKAGANGAITQYFFNADAYFKFVDDAY
KLGVDVPIIPGIMPITNFIQLARFSDNCGAEIPRWIRQRLNSYGDDSKSIFSFGIDVITD
LCDQLISAGTPGLHFYSMNKSKAIRKISKNLSCFK
>A0A2N2WUW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-3|TrEMBL
MKVTDHIKQAKGKTLFSFEIVPPQKGQNIQELYDNINPLMEFKPPFIDVTTSREEHVYIA
KGKGLLEQKITRMRPGTVGICASLKYKYNVDAIPHVLCGGFTKEETEYVLVDCHYLGLDN
VMALRGDAMKHEKYFSPTEGGNAYAVDLVTQITDLNRGKYLHELIETPYKTDFCIGVAGY
PEKHIESPSLDADLRRLKEKIDAGADYVVTQMFFDNQKYFDFVEKARAMGITVPIIPGIK
PIAIKRHLQVLPQVFKLDLPEALIWEIEKCSSNEQVREVGVEWSIAQSKELISKGVPVVH
FYSMGKSDNIKAIAKEVF
>A0A0D6N3R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter cibinongensis|TrEMBL
MRLKRETDLVPAAHLTCVGATREEVDDLARCYWDAGVHHIVALRGDPPAGATDYNPQPAG
YACASNLVAGLRRIADFDISVAAYPETHPTASSPDADLDNLKRKLDAGATRAITQYFFDS
EIYLRFLDRCLAAGITAPIIPGIMPVSDYEQIVRFSAVCGVTVPAWLRNLFDGTEENPDL
RRIVASMVAVEQIRTLQTYGLNEFHISTLNRADLTYAIAHSLGVRPIQTNASHNVTDPLE
TTEIPDERETSTDFDTTKGLQEGAPPLMLRTLFG
>A0A3G9GGG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquitalea magnusonii|TrEMBL
MNEQKKTFSFEFFPPKTPEGVAKLRTTRQQLAQFKPQFFSVTFGAGGTTRDGTLSTVLEI
RSEGHAAAPHLSCIGSTRENISAILNEYRNHGIRHIVALRGDMPSGMVAAGEFRYANELV
EFIRSEHGEHFHIEVAAYPEFHPQAKSAEDDLNNFVRKVKAGANSAMTQYFFNADAYFRF
VDEAQARGVDIPIVPGIMPIANFGQLCRFSDMCGAEVPRWLRQRMQSYYDDAASIRALGL
DVVTELCDRLLAGGAPGLHFYTLNQAGLVSTVWQRLGL
>A0A7Y5JG04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MEPLLEALKKRVLIGDGAYGTLFSRRGLTSPGLVSPLLNLAKPGFVRAIHEEYLRAGSEV
LETNTFGASRPVLEAAGVGDKAREVWRAGARIAREAAAQKAYVLGSVAPLGRAGLKLTPE
QRHTAYAEQVQGLVEGGIDAVLFETFSDLEDLQLAIAAANQTAPDTPVVAQMAFSIAGTT
TSGVSPERMIEGLKALRVDVLGANCGGGESAAIEVVRRMADHTDKPLSVFPNRGLADFDE
TGRPVYIEGADYFAKSARRLADLGANLIGGCCGTGPEEIRRLKSLLAGRRPSMRHRAVSS
SSGRRQAAVPAGPRVQKTLATDFAHGGVVIAEVDPPRGIDATEQMAGARLLMDAGIDAIT
IADNALSVMRMGNLALAQLFMAEFKARIVLHVACRDRSLLGTQSHLLAAYALGISNILAV
TGDPIATQAHQGSSGVFDMSSTKLIELISRINRGEFTAESDGELRTNFYIGAAFNSATRS
LENESKRLLRKQQAGAGFVMTQPVFSVESARAVAAAITPLNMPVALGIMPLVSERNAEFL
HNEVPGIQIPEAIRARMAGKSGKKGRAEGLAIARELMEQVADSFAGFYLITPMDRYEMIA
ELTTFARSLRVKARA
>A0A6M1SYM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Balneolaceae bacterium YR4-1|TrEMBL
MKVIEHYNRADEPLISFEIIPPKRGGSIKGVFDSLDKVMKYNPPFIDVTYHAAESYYEEL
ADGTIKRHIKRKRPGTIGLCAAILHKYGVDPVPHLICEGFTKEETEDALIELNYLGIDNV
LTIRGDAPDDNVPRFKNGTYNDHAIDLVRQVQDMNKGRYLEDISNAQRTDFCVGVAGYPE
KHFEAPNLDFDIQMLKRKVDAGGDYVVTQMFFDNDAYFRFVDKCRAAGIECPIVPGLKVL
TVERHLNFLPKYFHLNLPEELSEAVQKNPGNAREIGIEWSAKQCTELLEKGVPGLHFYIM
GDPSPALEVIEKIPMGTKVKANA
>A0A8J2XK32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sediminivirga luteola|TrEMBL
MPPPLSASAPSDADDAPASVRRPPRRLTLSYELFPPRSDVQARTLPDTIERLAATGPDFV
SVTYGAAGPRRATTTELLRFLVDQTPLRPLAHLTCVGNTEEQLREIIDEFLSAGVRGILA
IRGDIPDGLGWPPPGALRYGHHLVRLIREVEAERAIELAAGRVSIGVAAYPNGHPDSPGP
RHDIDVLLAKQRAGADFAISQQFYAPGEYLALLRRAELAGVRLPILPGIMPLTEPGRILK
LSRLAQIEPPAALLHELELARDETERHRLGVAATVRLIRAVLDEGAPGLHLYTFNNHRAA
LDVLDELGWPSAA
>A0A222SHE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prosthecochloris sp. GSB1|TrEMBL
MLVKEILASTSEPVFSFEFFPPKKHEDWEKLFRTISELIPYNPSYVSVTYGAGGSTRTRT
HDLVTRIQKETGLTVVSHLTCICSEKKEIGEILDNYRKHGITNVLALRGDLPPGVDSYAE
ATKDFPHAIDLVHFIVENFPDIGIGVAGFPEGHPETPNRLKEIEYLREKVDAGADYIVTQ
LFFDNRDFFDFAERCSLAGIDVPIVPGIMPVTTKKGLIRMSELALGARIPSKLLRQVLEA
ENDEEVAKIGIEWATAQAQEMIDNHIGGIHFYTLNNAEATRRIFENISTARTA
>A0A5F2EYH1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. S2017|TrEMBL
MGLLEELKTRVLTADGAIGTLLYSYGLDYCHEEMNIIRPEIVEKIHGEYIAAGADIIQTN
TYGANAIKLARYGYEGRVAEFNSAALEIAKRAATPGGQFVLATIGGIRGVRKSEATLEEI
LAAFREQAETLLAGAPDGFLLETYYDFEEISHCVNLLRTLTDLPIIAQVTMQEPGVLQNG
MSLNEALQDLERLGADIVGSNCRLGPFHTIQAFETVNLPKTAYLSAYPNASLLDVEDGRV
VYESETDYFARAAVELVNQGVRLIGGCCGTTPKHIAAVKQRLVNIVPIETKELKPGRTEF
VRVAEPRKQEPLHVKAKRERSVIVELDTPRHLEIEGFVEGAKKLASAGADVIMMADNSLA
SPRISNIAMAAILKEHGIRSLPHLTCRDRNLIGLQSHLMGLNALELHDILVVTGDPTKVG
DFPGATSVYDVSSMELITLVKQLNEGGSFTGKTLRKQANFSVAAAFNPNVRVLDRAVARL
EKKIEHGADYFISQPVYSKEKIVEIYEATKHLETPIYIGIMPLTSSRSAEFLHHEVPGIK
LSDEVLARMAACGEDKEVATKEGIKIAKELLDTACQYFNGIYLITPFLRYDMTLELMDYV
NQFDANNKGVQSNA
>A0A371YMK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sichuanensis|TrEMBL
MSQLSLHFQQNQFCVLVEYLTSFNEKFSVKTSFAGYPSLMTFADRVHSDHDIAPLEASQH
YPDTIDKVLHFAGKGRDIQDFEQFLQHAQAANIQNLLLLTGDKLKNHHDGQDESERTRYL
ESVNSIMAAKKYGGFTIGVAFNPFKYAEAERDAQYLKLHKKIKAGADFIITQLGYDITAL
KQSKNFLKHCHYTQKILACVMPLNLARAQFMLKNNVAGIVITPHMLKILADEKQTGQSER
MYLRCALQILMCKHLGFAGVHLSACHKAEEQILLESYIEQYRHLALDELERLWNSLWQIK
TGQEFIPKLAYFSRQPTSSQMIKYQQLHLMHDALFDSKLAKGVGKFIFKASFWENKPISK
ALLKTEFLSKHRVVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTNLDRCEFGDRECI
HSIKARLAKAVQQTQVLKDKLIPTVPLDRRGTSSWKNWYLATEAELY
>A0A560C973|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Azospirillum brasilense|TrEMBL
MTSGTPSVSFEFFPPKTEKMEQSLWQAIQRLAPLGPSFVSVTYGAGGSTRERTHNTVTRI
QKETGIPAAAHFTCVGATREEIDAIARTYWDAGIRHLVALRGDPPETEGGVGGRYVPHPG
GYAYAADLVAGMRKVADFEISVAAYPESHPEAPSAQFDLDNLKRKVDAGATRAITQFFFD
NDAYFRFLDRCAAAGITVPIVPGILPITNFARAVEFAGKCGAAMPKRFAETFEGLDSDPE
TRQLVAATMAAEQCQALQAQGIKDFHFYTLNRSDLTVAICRMLGVKAKQPAVS
>A0A2E3Z5I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetaceae bacterium|TrEMBL
MTLAQAYGSKKFGLSFELFPPKTESGMTNLFCHVERFVAYKPSYITCTYGAGGSTQDKTL
EVITKVRERYQLPVATHLTCVGLTAEQLGAYLQRAQDQGVENVVALRGDPPQGETEFVAP
RGGFGYANELVEFIRQQFPAMGIAVGGYPETHQEAPSPEADLVNLKRKVDAGADAIITQL
FFDNRDFFDFCDRCEQIGIHVPIVPGLLPITNGAQIQRLATLCGAKMPKTLVEQLHQHAD
DPQGQFNIGVEFATRQTSELLEAGVAGLHFYVLNKSEATDQVLRSVHWPR
>A0A503E417|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-5-7|TrEMBL
MTGRQLDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQMVADRLDRILHDDITETQVDMVK
TAH
>A0A2J6H5N1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter sp|TrEMBL
MKITEHIQNANGKTLFSFELIPPLKGHSIQGIYDAIDPLMEFKPPFIDVTSLREDFIYKE
QENGLLQKLAYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKDETENGLIDLHFLGIEN
VLVLRGDARRGDASFVPTPNGHCYATDLLQQVVNMNNGVYLHEHYDNMMRTDFCIGVAGY
PEKHFEAPNLKTDFKYLKQKVDMGAKFIVTQMFFDNQRYFDFVNGCRAAGINVPIIPGLK
PITSSKQLISLAKTFHIDIPEDLSDAIHEAKSEKDVKDVGIEWMINQCKELVKFGAPVLH
FYTMGNPGPTKRIAEAIF
>A0A2S1FAR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter schindleri|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTINDFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADNFDADIKRFCEKAHAGANTALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A829HH24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter gyllenbergii CIP 110306 = MTCC 11365|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKGVHQELQLLNPEFFSITYGAGGSTRERTLAAIHDFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADTFDGDIQRFVEKVNAGANAGITQFFFNPDAYFYFI
ERIAKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A832ID64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium|TrEMBL
MKISTFFKRNIFSLSFEVFPPKREGNLEQLYETIEELKELHPHFISVTYGAGGSTRDKTI
EIAGRVNNELKITALAHLTCVQATRDDIARTLDCLSERGIENILALRGDPPQGQEGFKAV
VGGFSYASDLVTFINDHGDFCIGVAGYPEKHLEAPDLDTDLRHLKTKVEAGADFIITQLF
FFNEDFYRFRDLAQKKGIRVPIIPGIFPLIHYQQIARTISLCGAKIPSKLAEKLERVKEK
PKEGEKYGIEFAVKQTSDLLRNGIPGLHFYSMNKSGPVKKIIEEIELPLPQAEIGLEG
>A0A2V7BKY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
APGLDPSKALAGAKMLLDSGVDIVNVADAPRAMARMSNIAFCSLLLERYGIQPILHVCGR
DRNLLAQMAHLLGAHAIGIRNLVIITGDPPKVGDYPEATAVYDLDAIGLLQMASNMNRGV
DPAGKPLPGGKTSFLLATGLEPGAADLDKELARLQKKREAGAELIMTQPIFQTDLLETVL
RRIEHLEMPVLVGVLPLVSYKNAEFLHNEVPGMQIPEVIRERMRKTPGGEAARKEGVKIA
REMLFAVRERVQGAYLMPPLGRYELALEVLDGLKR
>A0A8J8F3Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Natronococcus sp. JC468|TrEMBL
MSSDIQSMPTAEGMVELLEKPRFELMPFESIDEQLGHLPEGSEIAITTSPTLGLEATIEW
SERASERGYEIVPHVAARYVEDRDHLAEIARRLTDAGVTDVFVPGGDREEPAGEFESAYE
LLVALEELPYEFAEVGITGYPEGHAFLDDETLAESMAAKEPYATYIVTQLCYDPDAVLEW
IEEIRDRGVELPVEIGIPGVMKYQRLLGISQKVGVGDSVRFLKKTSGIVGFVRQLVGSRG
TYSPDTLLEGLAPYATDPYYDIRGVHIYAFNQVPDLESWRAETLEKHR
>A0A524H2C6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacterales bacterium|TrEMBL
MLTGGLEGAWLLMLRVFQNEILDPKRFVITMELVPGREPAGRSVDSIKGMATDAFADGRV
SAVSITDNPGGNPALSPDVIGHDIFKVGMDVIVHFTCRDANRIGMESRALQLAMMGMKNI
LALTGDYIGKGFAGQGAPVFDLDSVTLLVMLRMLGNRVQQAGDPDVFFPGCAVSPFKSLR
GEVFAQYAKLCRKVASGARFAITQLGYDTSRFKELMDVQQGLGLELPTLGSVYVLTPVSA
RIMNAGQVPGAVVSDELLNQVIREWKDKRQGRALAVERAARLGAVLKGMGYRGIHIAGVH
RGFDLVGRILDRMAHIEDQWRNFIDDFAPSKNKNGCSMGKKEQPRSSVCSPRVHLSFPDR
FHFRFLQIVHNQFFNFDALLAPLFRLMARRIGQRTAGRLLAQLFEDPVKTLLLECRRCGD
CAIQHVAFLCPESQCPKHIRNGACGGSRNGCCEVVPERKCVWFRAWERLADAGHPEEMVT
DCVPPRLWELDGTSSWLNFHLRRDHQSASGEVLQACRATECRIPPTIPF
>A0A2V6RAM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MAHAFSERLAAGPLLCDGAMGTLLYARGVPLDGCFDVLNLNTPALVQAIHSEYIAAGADC
IETNTFGANRFKLAVHGLGSQVREINLRGVKLARDVREAMGRDVLVLGSMGPLGKYLAPL
GTLGEGEARDAFREQAEGLLEGGVDAFVVETMSDLGEVALAVEAIRAVADLPIVAQVAFT
DEGLTFLGRTPAEVARALSALPVQVIGANCSVGSSTLYEVLEQMRPAAGGRPIAIQPNAG
LPSRVGERLIYLSSPAYMADYAARMLAAGARVVGGCCGTTPEHIRAMRAVTGPTPSARAV
GRAAAPAVARPDQAPVMRTAAPPTRLERKLAAGEFVVTVELDPPRGHNIEKLVQGAKLLK
ERGAEIVDINDGSLGRIRMAVLPTAVLVRDATGLEINMHFTCRDRNLMGIQADLLGAHAL
DVRNILAMTGDPPRAGDYVNATAVFDVDAVGLLRILRRMNGGLDATGSSIGEPTAFCVGA
VLNPAAREPELEVERLRQKLEAGAQWVQTQPIYDLALLDDFLRRAGSPEVPVLVGVMPLH
SARHAEFLHNEVPGITIPPEVRARMREAGDKGLAVGIELAQGILRQARRRYAGAYLMPSF
GRYEVVAEVLDALR
>A0A2V7CX76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium|TrEMBL
MTYELSRRLAAGPLLCDGAMGTLLYARGISLDACFDVLNLNNPRVVQSIHADYIAAGADC
IETNTFGANRFKLAIHGLDKQVREINRRGVALARDVRESSGRDVFVLGSIGPLGKYLAPL
GTVTPDEARSAFHEQAEALLEGGVDAFVVETFSDLDEVALAVAAIRAITDVPIIAQMAFT
DDGTTFTGRPAADVARALRALPVDALGANCSVGSSTLYEVLEQMRPEAGSLPLCIQPNAG
LPSRIGERLIYLSSPAYMAEYAERMVGAGARLVGGCCGTTPQHVAAMREVLDRRRPARPE
ARTTAVTVSPVATGVSPGLHVARPPTLLGRKLAAGEFVVTVELDPPRGHSVEKLVQGAKL
LRERGVDIVDINDGSLGRVRMAVLPTALLVREATGLDINMHFTCRDRNLMGIQGDLLGAH
ALDVRNILAMTGDPPRAGDYANATAVFDVDGVGLIEILRRMNEGQDATGSSIGEPTSFYV
GAALNPAAEDAAREIDRFDRKVRAGARWIQTQPVYDLAELDRFLERAGGSPVPVLVGILP
LHSARHAEFLHNEVPGIMIPEDVRRRLREAGDGALRVGIEMAQELVRAVRRRYAGAYLMP
SFGRFEVVAEVLDAIR
>A0A6A7M105|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillales bacterium|TrEMBL
MSPDTGPLGGPYSVSSAEFPARAPQRLKVSFEFSPPKTEAAERTLWETVTRLAPLQPTFF
SVTYGAGGSTRQRTHETVARLKKETGVDAAAHLTCVGATQGEIDEIARAYWDAGIRHIVA
LRGDPPSGMGGKYSPHPGGYANAAELIAGLKKIGPFQISAACYPEKHPDSADAKADLENL
KRKVDAGADRCITQFFFEADDFLRFRDSAAAAGVNAPIVPGIMPVSNFQGITKMAGLCGA
KVPTWLAHLFDGLDDDVETRRMIAATVAGDLCRRLRDEGVDQFHFYTLNRADLTFAICHL
LGVRPQ
>A0A1I1MFX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus albus|TrEMBL
MKTCELFKNKTTLSFEVFPPKSDTPIDSIYSTIDGLAPLKPDFISVTYGAGGNGSNATIG
ICEMIKEKYSIEPVAHLACINLTREKVLFELAQMKTAGIENILALRGDINPNIPPHNDFK
YASELINLIKEQGDFNIIGACYPETHPEAASSVDDIKHLKEKVDAGCSQLISQLFFDNED
FYAFREKCAIAGIDVPIEAGIMPVTNPKTIARMATLCHARLPKKFLTIMDKYADDPISMR
DAGIAYAVSQIVDLIANGVDGIHLYTMNNPYIATKICEAVQSLFN
>A0A1M7ATZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas caseinilytica|TrEMBL
MSAPQSPLDISFEFFPPNTDAGRDKLMRARDALASREPRFFSVTYGAGGSTQHRTLDAVK
AVRECGIDTAPHLSCVGSEKAQLRDLLTRFREDGVKRLVALRGDLPSGMGGVGELRYANE
LVEFIREETGEHFEIAVAAYPESHPQAPSFERDVENFARKMQAGADLAITQYFFTAEAYF
HFVDRARALGVEAPIVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSEAIAAF
GEDVISGLCQRLLDGGAPGLHFYTLNQAEPTLKVLDNLRT
>A0A2T7LV62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CS090A|TrEMBL
MALGTASTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMIGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCDTPVIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCATLLSEGVPGLHFITLNNSTATLEIYENLG
LHKQS
>A0A0H3BLM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella newport (strain SL254)|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRNSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2W4B4L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterococcus plantarum|TrEMBL
MRTDILFKKKTVFSYEIFPPRRSAPIETIYHTLDRMKGQQPDFISVTLGAGGTGENLSTA
EIAQKIQEEQFLPSVAHLPAVNFSKDEILIILEELKEKKVENILALRGDILPNKEPKKDF
SYASDLVAFIQEQGDFNIIGACYPETHGDAESSVEDIRNLKRKVDAGANQLITQLFFDNN
YFYTFKEKCDIANINVPIQAGIMPVVNRKQIERMIKMSSVTLPTKFLKMMERYEHNPEAI
RDAGIAYAINQIVDLVAQGADGIHLYTMNNPYVAQKIRDATRSLFNA
>A0A7W9BF10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas aerophila|TrEMBL
MTISVSQLSEARVALDAPLYADVAGDMEVSFEFFPPKTEKMDEQLWSAIRTLEPLGPSFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATREEIDAVADEYWAAGVRHIVA
LRGDSPTPGVPYAQHPGGYENAAALVAGLKRLHPFEISVAAYPECHPDSSDAMADLDNLK
RKIDAGGTRAITQFFFEPETFFRYRDAAAAAGITADIVPGIMPVTNFASVQRMAAMCGTA
VPAWLARLFDGLDDLPGARQLVAATVTAELCRKLYAGGVRQFHFYTLNRAELAYAICHLL
GVRARSISQEAAA
>A0A243GE11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis subsp. finitimus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKRLIDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRAILNVKPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIKEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7G8IRQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. A18-25c|TrEMBL
MGSALQRSLEAGSVTVTAEVMPPRGGDPSHALAMAEGMRGWVQAINVTDGSRAVMRMNSV
AVCRLLLDAGLEPVLQMAGRDRNRIALQADLLGAHALGIRNLLCLTGDPVQAGDQPHARP
VHELESIRLLKQVSAFNRGEDPVKNNLPDGPTDLFAGAAADPHCPSWSGLTRRLERKREA
GARFLQTQMVMDPRVLERFCRELATPMELPVLAGVFLLKSAKNAAFINRMVPGACIPDDL
IARLAAADDPASEGIAIAAEQVHRYLGIAQGVHVMAVRAEERIPEVLKKAGLSSQPL
>A0A510WW42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter johnsonii|TrEMBL
MSLLAQYFAQQQFCVLVEYLSSHQAQWPVKTQFAGFPAAMTLADRVHADDDEAPLQVAKQ
YPQEIEKVIHFSGKARDIQDFEQFLQDAKTQGQKNLLLLTGDKLKQHHYSHDLKPRTRYL
ESVNAVMEAKRQGGFHIGVAFNPFKYAEAEKEAQYLKLHKKMKAGADYVITQLGYDMTAL
QDAHAFLAQHQYAQKILACVMPLTLARAKFMLKHKVAGIVITPHMLQVLQQEKEQGLSDR
VYVRCALQILMCRHLGFAGVHLSACHQPEEQSFLERYIEEYRHLSFAECEQLWNTLWQVQ
TGTEFHPKLAYYSRPATSSQIIKYQHLHLMHDALFESKLAKGMGRFIFNFNVWDRSRAKQ
ALLKTEHLSKHAVVGCESCGQCRLGETLYICPETCPKGLANGPCGGTSLDRCEFGDRECI
HSVKARLAKAVGQTKILKEKLIPTVSIAVRGTSSWKNWYVEAAS
>A0A5D4R206|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus pumilus|TrEMBL
MGLLQDLQNRVLIADGAMGTLLYSYGIDRCFEELNLSKEDEVKRVHEAYVQAGADIIQTN
TYGANYIKLSRYGLEEETKRINTKAVQIAKAAAGSAYVLGTIGGIRTFNKNAYTIEEIKR
SFREQLYILLNEQPDGLLLETYYDMEEAQAVLQIARKETPLPIVMNVSMHEQGVLQDGTP
LKDGLSELSSLGADVVGINCRLGPYHMIQALEGVPLLENSHLSVYPNSSLPSLEEGRLVY
DTDNDYFRKSALEFRNQGARIIGGCCGTTPQHIHAMAEAVKDLAPITEKEVKVLKEEIIS
IQDQRTEPGLDELAMKKRTIIVELDPPKKLNFEKFLVAANELKNAGIDALTLADNSLATP
RISNVACGALLKQQLDMRSLVHITCRDRNLIGLQSHLMGLDTLGLTDILAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSFSGKPLGKKTNFSVAGAFNPNVRHIDKAVKRLE
KKIEYGADYFISQPVYSEEQLVKIHEESRHLDKPIYIGIMPLTSSRNAEFIHHEIPGIKL
SDSIRDIMAKAGEDKEKQRAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTTYIH
QKEKESNTHVNYH
>A0A821MZ45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ranitomeya imitator|TrEMBL
TGYPKGHPEAESCDSDLRHLKEKVDAGADFIITQLFFRSETFLQFVKDCRVIGIACPILP
GIFPIQGYGSLRQLVKLSKLEIPQEIMDVIEPIKDNDAAIRNYGIDLVVSMCRELLDSGL
VHGLHFYTLNRERGLTSIVLRHGWLWQGLRRRPLPWAVSAHPKRREEDVRPIFWASRPKS
YIHRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRDQLLKMWGEEQSSEESVFE
VFTSYITGKPNRNGHKVTCLPWNDDPLAPETNLLKDELEKVNKRGILTINSQPNVNGKPS
TDPVVGWGPSRGYVFQKAYMEFFTSSETVTALIKVLKRYEPRVNYHIVNVQGKNITNSTD
LQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWAKLYEEESPSRMIIQYIH
DNYFLVNLVDNDFPLESCLWQVIEDTFQELDNPTEQ
>A0A4P7GW89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermaerobacter sp. FW80|TrEMBL
MGRDAPSTPLGEPAGPLQFAPPFLALADADPSWTLAAEAGDAGAQGGTDPDGTGRAAVAG
AAAVAWWPLTRPRPVEAVHLTAIRSGARLIRTHTRWANAAWLQDATAAQVQDLNLWAAKL
ARSAREVAGEPCLVAGYLGPLPPAAASLADHDPAAAVGWYRDQVAGLLAGGVDLFWIAAR
TVAEARGALQAAREAARLPVGLLWEPGGEAGAMGADAQAIQLVAALQATGMPDALGVAVT
GGPAEAAPWLAALRDAGWAGPLWVSLGEPETPEPSEAGGRAPGTGGGPVVGARGRTRDTG
NEPVAGAHRRAAGTGSEPVPGQPDGRGDGRPTRRSGARGNGSPTAEEQADPWATLRLLGV
SWVAGTGARSPARFATLARRLRQAGATAPRPAAGEAGGWRADAPPSAVRATGGASVPRGP
AEPCGPEDPVNRTASAAAPTGTAGAPAATAGAGLPADRADTPGAPDAATVAGTNRRGVAG
PGTPAWGGGTGGGVPPAPAEDRLARPLPLREKLGRRFVISVELDPPRGPVTTKFVADART
VAAAGADAVNVGDSPMARPRMAALAGAYLVRHAAGIDAIMHCTTRDRNLMALQADLLAAH
ALGVRNVLALTGDPPRLGNSGASPVYDVDSIGLLEVLAALRRGEDPQGNPLGAPVDFTVA
CALSPNADDLERELERFRRKLAVGVVDFVMTQPLYELEPLERVLDRLGGCPVPILLGVMP
LHSGRHAHYLHHQVPGISIPDAVREALDKAGDRGLEVGLELAEAVVEAARPYIAGVYVVV
SYGKAEPVAAFVRRLRARFDEPRPAAEGAGATAPRPATAGSAAAWPTDHGSSTPGGGIGP
RADFPPASGAASPVEQGEVRHHAG
>A0A4R2IF19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dokdonella fugitiva|TrEMBL
MASPAPISFEFFPPKTDEQRATLEAALPKLKALAPEYVSCTFGAGGSTLSYTPETIRHLR
EEHGLDAAPHLSCMGGTRAEIRELLDRYTRMGCRRIVALRGDLPSGMASYGDFRYASDLV
AFIRGECGDRFHIEVACYPEVHPQSDDAHADLRHFRTKVEAGANGAITQYFYNPDAYFRF
VDAARRAGIGVPIVPGIMPIANFSQLKRFSDLCGAEIPRWLGKRLHAYGDDVESIREFAA
DVVADLCDRLVAGGAPGLHFYTLNRARATLAVIERMRR
>D8PVA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schizophyllum commune (strain H4-8 / FGSC 9210)|TrEMBL
MKLADKIKQHKGPHPFFTFEFFPPRTDQGFENLVPRICRLAELDPLAISITWGAGGSTKE
RTLELAGVTQEQNGLDTVMHLTCTNMKVGMVDEALAAAKERGIESILALRGDPPRGQEEW
TPIDPRFQHGIDLVKYIRSSPYAQTFSVGVAAYPDGHTERLNDEDTEIGFLKQSVDAGAD
FIITQLFYDVDNFVRWVKKVREAGISVPIIPSVMPIQTYATFIRLTKLCGSRVPESIMTA
LEPIKSDDRLVKDYGVELAVEMVRRITTEAGIPGIHLCTLNLEKSVTRVLEILKWTPAHA
AAAASAQPSITGHNSLIADGPASTVVHPPPQLDAADLVLTPGAATDKATHGLKDIPAVGA
PAGSGELNNAASWDDFPNGRFGDVKSPAYGELGPWGSFGQAYTNALSSTSAGNPTTLDEL
TKIFVDYLEGKIPTTPFSPTALSPESKIILPELRELTARGWWTVGSQPAVDGVSSADEVV
GWGPRAGYVFQKCFVEFFCEEADVEQVSRAVEANGYGWVDWFAGNYQGDLRGNVPEGGRN
AVTWGVFPGQEIVQTTIIERESFCSWKEEAFDIWSDWAGFYRPGSEERKLLENVRDTRWL
VSIVHHDYKDPDALWKFLRGVGTEDVC
>A0A327ZFU6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes lutulentus|TrEMBL
MSLGLPSRLPGTPSIGALIREPAPTFSFEFFPPKTHEGERLLWQAIRELESLKPSFVSIT
YGAGGTTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRNVIGRLAGAGVRNVLAVRG
DPPGDPMGEWVRHPDGVHYAEDLVRLIKESGDFSVGVAAFPYKHPRSADVESDTRDFVRK
CRAGADFAITQMFFEADDYLRLRDRVAATGCDAPIVAGVMPVTRMATIERSQQLSGAPFP
QALLRRFERVADDEAAIRELGIETCAQMCARLLDEGVPGIHFITLNRSTATREVWQRLAP
AEVATAA
>A0A521NXK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Variovorax sp|TrEMBL
MASPLLHSDKSKPIGNITDAYSLEVNAKDISALTAAAPRVLPGSTISIPYLANQDNDARL
AAAQAVRGLGFEPMPHLAARRIASFAKLESFIQRAVAEAGVKRCFVIAGDPSTPLGPFAD
SSSLIESGVFERSGIQMVGVGGHPEGHPVMSTSDRWKVLEHKCRCIEGRGMAPLIVTQFA
FDADIVLAWLEALRGRGVEHPVRVGVPGPAGVAVLARYAALCGVSACASMLSKYGISISK
LFGIAGPDLFVDRLTTRLTEAHGKVSLHFFPFGGIAQSVKWVEQYCSRAEPEQPIDTAPM
>A0A117LS37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfotomaculum sp. 46_80|TrEMBL
MALRGDINPDIPPKQDFKYASDLISFIRKNSDFNIIAACYPEGHREAASIDADIHNLKIK
VENGVDHLISQLFFDNNYFYAFLERAEHAGITVPIEAGIMPVVNKKQIERMVSLCGVDLP
RKFTAMMNRYENNPVAMRDAGIAYAVDQIVDLVSQGVDGIHLYTMNNAYIAQKINEAVKS
LLISPR
>A0A8B3JV46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter mori|TrEMBL
MSFFHANQREALNQSLAEVNGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVALLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPLWMSKMYE
GLDDDPETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGV
>A0A6H1LHY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. RLB1-33|TrEMBL
MALGSASTRTDRARTVRDMLATGKATYSFEFSAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPRGLTYAAELVRLIKDAGDFCVGVAAFPEMHPRSADWDVDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVVAAGCTTPVIPEVMPVTSVKMLERLPKLSNASF
PDVLKERILTAKDDPAAVRSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A2N9NBC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Sulfotelmatobacter sp. SbA7|TrEMBL
MATDLLARIKQSPVLCDGAMGTLLYAKGIFINRCYDELNLTQPELIRGVHREYLQAGAEI
IETNTFGANAFRLGRHSLADRVRDVNLAGAHIAREAAKSFDVWVGGSVGPLGIRIEPLGK
TSFEEARAAFRDQIAALVEGGVDLLIFETFGYLEELHQAMLAVREVNPKIPVVAQVTIDE
DANCLDGSTPEAFTPRLAEWGADVIGCNCSVGPVAMLDGIERMRAVTSLPLAAQPNAGIP
RSVEGRNIYLCSPEYMASYARKFVAAGVRLVGGCCGTTPDHIRVMKSALRVGEARARVGS
SPAAKPAGPPAAPAVPIVQRSRLGAKLAGGEFVTMVEIVPPKGTDIHKEVEGARFLKSVG
VDAINIPDSPRASARMSNQALSLLIQQEVGIEAILHYTCRDRNVLCIQSDLLGAAATGIR
NLICITGDPPKMGNYPDATAVFDVDAIGLVNIVHNLNRGMDIGNNPLGRGTSFVIGVGAN
PGLPNMDEEIRRFEYKVEAGAEYAVTQPVFDLGLLENFLRRIEHCRIPVVAGIWPLVSVR
NAEFMKNELRVSVPDSILERMARTATPEAAREEGIAIAREMVMAIREMTQGAQISAPQGR
YNSAVDVLEALGTSRPTSV
>A0A3D2NA89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp|TrEMBL
MNVIDILNDSSRPNGFSIEVLPPLKGNGTGALFRNLDKMCEMKPLYVNITTHHSEYVYRE
LEGGHYERQRIRRRPGTIAIAAAIQKRYGVMVIPHVICSGATAEDIEYELIDLQFLNINN
VLLLRGDKAKDDKTFKPVLGGYAHTTQLIEQVNRFNEGFFVDGTPIKHPGDPFHYGVAAY
PEKHEEAPNIDMDMAYLKQKQDMGADYAVTQLFYDNRKYFDFVKRARAMGITIPIVPGIK
PFAKCSQITMVPKTFHCDMPQELAAEAVKCKTDDDARALGIEWTVNQCRELFAAGVKDIH
FYTVSAVDSVVEVAQQLM
>A0A258DFE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiotrichales bacterium 32-46-8|TrEMBL
MPITNHDQLARFSDACGAEIPRWLRKRLEAFGDDKAAISELGLEVVGDIGERVMRGGAPG
VHYYAMNSLEPARSLMERLRSFST
>A0A5P1DT77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. JG-B|TrEMBL
MSQERRYSFEFFPAKTEAGHEKLMATARTLANYQPDFFSCTYGAGGSTRDRTLQTVLQLD
GEVKVPTAPHLSCVGDSKAELRALLAHYKDAGIQRIVALRGDLPSGMGMASGELRFANEL
VEFIRAETGDHFHIEVAAYPEVHPQARSYEADLANFVRKVKAGASSAITQYFFNADSYFY
FVERARKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDVQSIQSFG
EQVITEMCEQLLQGGAPGLHFYTLNQAEPSLAVWKNLNLPR
>A0A0K2J8E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia sp. oral taxon 212|TrEMBL
MKIKDIFEEKEHIISFEIFPPNKNFSEERLKEVTSELIKHKPDFISVTYGAGGTTKSGTI
EMSSHIKNNLKSEVLAHLTCVGSKKTEIASFLEEAKNHNIKNIMALRGDIPQGEDESIYE
KGDYRYASDLIRNIKETHDDFSIGAAFYPETHYESNDLADIVHLKKKVDEGVDFLISQVC
FDNRMFVDFREKTEKLNIKVPLIAGIMPVTNAAQIKRIVQLCKSSIPSGLEKILDKYGSN
PESMKKAGIIYATEQIIELLSYGIRGIHLYTMNKTDTTEEIMKNISFAR
>A0A3D1CZV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp|TrEMBL
GDGPAHATDLIEQVNRFNGGHFWDGTEMKCKGEPFHYGVACYPEKHEEAANLEADLAVLK
MKADLGAEYAVTQLFYDNEKYFSLVRRAREAGITIPIIPGIKPLAKLTQVTQVPKTFHCD
MPQELAKEAVKCANDEDVRQLGIEWAVSQCKELYANGVKDIHFYTVSAFKSMPDILRQIL
>C3XGW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter bilis ATCC 43879|TrEMBL
MLEQLITKLQSNEPFLSVEVSPSLSSTIGQSVIDELESLSQADCFVCTDSPLARLKPSSI
LSSIKLQNALKKPLICTLSMRDRNSIALCGDILGANEFGLRSFLSLSGDGVKNGDCAGAK
GVFEESSLKLGRIIDGLNQGIAANGKVLKNSVETIYNFSVINSYANNTESLKKKMLKKLS
NSAVQGLFTQPVFSLEGARFLLESLESINKELGQNCVMILGFFPVLSYKVALFLRDKLPG
VYIPDEWVQKLEKASIKGKEVERKVGLELSRELFKDLQTLHNKFHFMSANKPSLLREFV
>A0A3S9A7V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus albus|TrEMBL
MLRDKLLARKPGIISYGMTPPKAANTSEKIAEIAQKQCERLRDLELDALILYDVQEEADR
IEQERPFPYLQTVSPDTYSKQYLSGLDVPKIIYNCVGNHSEAEFTDWATKDADQDRYSVF
VGSSSNKQHVHLGLKDAYQLTKQLNRNLTFGGVIIPERHMTKQDEHLRVVSKMKNGCDFF
VTQAIYNVEASKNFLSDYYYYCSENGIEMVPILFNLAPCGSTKTLEFMKWLGISIPKWLE
NDLKYSSDVLDQSIRHCQKIFEEIFEYGLEKGIPIGCSIESVSTRKVEIDASVELVQNIK
ALLKTKLESTLV
>A0A5D0XV89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter echini|TrEMBL
MTELDTRVEVIPGEALLERLLDHVPAPAVVSVTCLPHHGPVQTVETAVRLAGAGYTVIPH
LAARSVGSRRELAGHVRRLQDAGITDTFVIGGDAGRTAGPYTWSGALMEDLADLTGGTMR
LGIAVYPEGHAGMPGDELLRTLWAKQELASWCVTQLCFSPEILAAFPDRLRRDGVTLPVW
AGIPGPVRVSRLVKLAGTIGVGQSVGFLKRSAGGSNTGSVVRQLLSSTSYDPSPLLGAID
GAGYAGVHLYSFNDLAGLADSGLAGRTG
>A0A3C0D5N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotella sp|TrEMBL
MNIADFLHQQGDKRGFSFEVLPPLKGNGTAALFRTIDALSEFGPRFINITTHHSEYVYKE
LENGLLTRQRVRRRPGTVAIAGAIQNKYDIPVIPHIICSGATKEDIEYELLDLQFLGISN
ILVLRGDKAKEDRQFTPTENGHAHATDLLKQVNQFNDGFFFDGTPIKHPGDKFCCGVACY
PEKHEEAPNLEMDMQHLLEKQQLGAAYAVTQLFYDNEKFYAFVEKARQIGVTIPIIPAIK
PFAKLSQLTVVPKTFHCDIPEELAQEVLKCKTDDDAKQLGIEWTTAQVQDLFEHGYNNVH
FFTVSAVDSVKQIAKILF
>A0A258H7L4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. 32-66-10|TrEMBL
MSIDRDPSSPPLFADVAGDIDVSFEFFPPKTEAMEKTLWESVETLSPFDPRFVSVTYGAG
GTTRERTHNTVARIARETPIAVAAHLTCVDATKAEIDAVAEEYWAAGVRHIVALRGDPPR
AGEKYATHPGGYENAADLVAGLRKLHPFEISVAAYPECHPDSPDAAHDLDNLKRKIDAGA
NRAITQFFFEADTFLRFRDAAAAAGIDAEIVPGIMPVMSFAAVQKMSAMCGTDVPAWMAR
LFEGLDDHPAARQLVAATLAAELCRNLYAGGVRQFHFYTLNRAELSYAICHLLGVRPRGA
AASAAA
>A0A0T6AK52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium CSP1-6|TrEMBL
MAMSPFLSRLAEGPLLCDGAMGTMLYAGGVPLDGCFDVFNANNPTLVQSIHAAYLSAGAD
LIETNTFGANRFKLALHGLDARVREINARGAKLARDVRETTGREAFVLGSIGPLGKYLAP
IGTIGVEEGRAAFREQAEGLLEGGVDAFIVETFSDLGEIRLAVEAIRALTDELPIIAQMA
FTEEGVTFVGRSAVEVARALRGLPVQVIGANCSVGSSVLYDILEQMLPEAGGLPISIQPN
AGLPSRVGERLIYLSSPAYMAEYAGKMLEAGARIVGGCCGTTPDHIRAMRAAVDRHVPTR
ARAGRVSVSPPAREEAPALRTAAAPTPLARKLEAGEFLVTVELDPPRGHNIEKLVQGAKL
LKERGVEMVDINDGSLGRIRMSVLPTAVLVREATGLDIIMHFTCRDRNLMGIQADLLGAH
AMGIRNILAIKGDPPRAGDYVNATAIFDVNAIGLIRIIQGMNGGLDATGNSIGEPTGFHV
GAGLNPAAVDPDKELARLFRKVEAGARWAQTQPVYDLEVLDRFLSRAGRLPIPIIVGLLP
LHSFRHAEFLHNEVPGITIPDAVRARMKEAGDRALRQGIEMAQVLLQQIRTRYAGAYLMP
SFGRYEVVAEVLDALR
>A0A7C6JNX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrimonas sp|TrEMBL
MKVSELVNATQKTAFSFELLPPLKGNSIQQVFNAIDRLKEFDPKYINITTHHSENVYQED
EKGVYRKVNVRRRPGTVAIAATIQYRYGIRAIPHIISRGFSKEETEYALIDLSFLGLTDL
LLLRGDAKNLDAEQRAMDSHLHATGLQEQVNNFNKGIGYDGAPFTAPEESFSYGMACYPE
KHEESPNMESEIYYTKMKVDNGADYLVTQMFFDNSKYFEFVERCREAGITVPIIPGIKPI
HLMNQLTVLPRIFRTDIPEELASELRKCKDDEAAKEVGVEWCIKQCRELVQSGVPSIHFY
ALMATESVYRVAKEIY
>Q5SLG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)|TrEMBL
MKIRDLLKARRGPLFSFEFFPPKDPEGEEALFRTLEELKAFRPAFVSITYGAMGSTRERS
VAWAQRIQSLGLNPLAHLTVAGQSRKEVAEVLHRFVESGVENLLALRGDPPRGERVFRPH
PEGFRYAAELVALIRERYGDRVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQ
LFFNNAHYFGFLERARRAGIGIPILPGIMPVTSYRQLRRFTEVCGASIPGPLLAKLERHQ
DDPKAVLEIGVEHAVRQVAELLEAGVEGVHFYTLNKSPATRMVLERLGLRPASGQP
>A0A5K6CNY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain AB307-0294)|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQQLNPEFFSITYGAGGSTRERTLAAIEDFN
GKGTPVAPHLSCIGDDKTRIAELLDLYKAQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLDKAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQVEPTRQLVVDLGLN
>U3P7I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leifsonia xyli subsp. cynodontis DSM 46306|TrEMBL
MSRTDARYSFELYPPRNERAAAALPATIDRLAATRPDFISVTYGAGGSSRASSLEVLRSI
LERTDVSPMAHLTCVGSSHAEANRLIREFLDAGIQRFLAVRGDLPADLAPGEDGLGDIKS
SAELVQLIHRVQAERVPYGELDVPELGAQAVLRHRERVQIAVAAFPNGYPASHSAAQDID
TLLAKQAAGANLGITQLFFHAEDYLSFAQRAKEAGVLFPILPGIMPVTSPSRLKRMLELS
GEDLPSDLAIQLEIEPTEEGQREIGIGWAARLAERLLAGGAPGLHLYTFNQHAAVLSVLE
RIGLLPDHATITKENEPA
>A0A0L0HK41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spizellomyces punctatus (strain DAOM BR117)|TrEMBL
MKITKKIEKALAEERCFWSFEYFPPKTETGVINLYDRMERMYALGPEFIDVTWNAGGSSS
DVTMQVCTTAQSVYGLETCMHLTCTNMPREKIDIALRDAKAAGIQNILALRGDPPRGQEN
WTKCETGFSYARDLVKYIREEYGDYFCIGVAGYPEGHTENPDKEEDMQHLKAKVDAGANY
IVTQLFYDVDLFLDWEKQCRAIGIDIPILPGIMPIQSYGGFKRMTTLCKTFVPKEILDDL
EPIKDDDKAVKEYGVKLAVKMCNTMKDAGIRGFHFYTLNLERSTRLILEGLGFVAPIELA
RPLPWNPSLAKNREKENVRPIFWKNRTRSYILRTEAWDDFPNGRWGDARSPAFGEIDGYG
FNLKYPADECLQMWNHPQTEKDIFNLFAKYCMNELNALPWSDSPLYPESDVIRTRLADIN
SKGFLTINSQPAVDGAPSTHPIYGWGPKNGFVYQKAYLEFFVSPEALDNIITKVSSHPYI
TYYAVNKQGDLRTNTQGDSPNAVTWGVFPGQEIIQPTIVESVSFMAWKDEAFELWNKWAC
LYEPESQSAKVIQNIWDTWFLINIVDNNFKDEHAIFTIFDDGTTSPPASR
>A0A0V0ZIL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichinella patagoniensis|TrEMBL
MPALLMPSVPKGMSNIFVITYGLLNNMNKKGNFKVAKVGNPSQQTDFGVYFEEDSFLSLM
ASLEAVELKATRHDLNSAAKKSTDEIYRPLIDRIKENISSGRRFFSLEFFPPHTTEGLIN
LLKRVDIFANSQPLFVDVTWVMRSDPASEKVTSSSSLADCILNFCLLDTMLHITSVQYDE
KTVLFNLERAKKIGIRNILALRGDISDDANVTTTDFQYACQLVRFIRSHYGDYFTICVAD
AGADFIITQLFFNEMHYFKFVGDCRKIGIVVPIIPGILPIQSYQSIMKIVQLSKIVIPDS
VLTTLESIKENAEAVRNFGISFAVQLCRKSILEQIGFWKKAPVRMFPWKKHTVHSVRCRE
AVRPIYWTARPKSYLCRTRDWKQFPHSRWGDVGIEAFGDLKHYLFSCIDQMDDSCALDMW
DKELSTLEHVRDIFCNFIARTPNRHGHSVRRLPWNENHLDPAADMLKNELIYYNSNGILT
INCQAAVNGLPSSDPIFGWGEANGYIYQKGYLEFFASSTCTTILLNHVQNFPSINYHAIN
FDGSFETFNYDEDATVALTWGVFVGQEIVQPTVANAASFRVWKDEAFDLWQRWAGLYESG
SIGRKLLQRIHDDYRLITLIDNDYPQPCSLSALLRAVISDYWGKKLDDG
>A0A2T8FBG5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides gansuensis|TrEMBL
MTLGRGRSMRELIEGGERSFSFEFFPPKDAEGEERLWRAITELEPYRPTFVSVTYGAGGS
SRDTTVRITGRIARETGLTPVAHLTCVGHTRDELAQILDEYRDGGVFHIMALRGDPPGGP
HTEWVSTDGGLEYASELVAFIKEHYGAAVGVAAFPEGHVNAESLEQDTQVLKAKYDAGAE
FAVTEMVLRASDYFGLVERARAIGVDFPIIPGIMPIVNLRSMHRMVELSGRQMPPEVTAR
IEPLADDPEALRAEGIRISTELCEELLAGGAPGLHFYTLNFSRATREIFAALQITA
>A0A067TBX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Galerina marginata (strain CBS 339.88)|TrEMBL
MKITQKIQQSHKEDKVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS
DLTSEMVKTCQGLIGIETCMHLTCTNMPKEKVDIALQDAKQHGCRNVLALRGDPPMGKDE
WEAVDGGFVHGIDLVKHIRREYDDYFDIAVAGFPEHMTLPPDELEREIQWLKEKVDAGVS
FIFTQMFYDVQLFIDWVKAIRAAGITIPIVPGIAPIQTWNGFQRATSLAKITIPQLYLDA
LEPVKNNDEKVREIGTRLVAEMCRAILSADIGIRGLHFYTMNLEKGTKMLLEELNLVPRI
ETIKPLPWRQSLTPNRRQETIRPIFWANRTKSYISRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEDAVKLWGYPTMFADISTLFTRFCTSDLKALPWSDQGVATETSVISKQLA
QINELGFLTINSQPAVNGARSDDKVFGWGPSNGYVYQKAYLEFFVNPNLLTLLLSQIERD
SNITYYVINKRGDLRTNTHSDGPNAVTWGVFPGKEIIQPTIVEAVSFMAWKDEAFELGTQ
WAKLYEHNSPSQKLIAEFMETSFLVNVVHNDFHDGDAIFRPFYKAGAEYLAINSKTTAVN
GH
>A0A5C8ZBV6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reinekea thalattae|TrEMBL
MNTPVPVSFEFFPPKTDAGFDNLLKAHTELKAANPEFFSVTYGAGGSTQERTINTVIEMN
SRGVPAAPHLSCIGSTLDTVHELLTRYKDAGIKRIVALRGDLPSGMRGTGGDFNYASDLV
RYIKSEFGDAFAIEVAAYPEMHPQADNLDKDIDNFVAKAQEGADSAITQYFYSVSAYTNF
VSEVRKRGCDIDIVPGIMPITNYSNLVRFSDACGADIPRWMRKSFEACGDDSKRIHQLGV
DLIVNLCKDLIAAGAPKLHFYSMNRSEPTLAILEKLTK
>A0A0B0D238|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacillus sp. BBL2006|TrEMBL
MKLNEALQKQTLIGDGAMGTLLYSYGIDHCFEELNLSHPEEVLNVHKAYVQAGADVIQTN
TYGANYVKLQRYGLEDQVKEINTAAIQLAKQAAHSSAYVVGTLGGIRGIQKQAVSLDEIK
RSFREQLYCFLFEEVDGLLLETYYDLEEILTVLEIARKETDIPIIAQVSMHEPGVLQDGT
SLTDALKQLEDKGASVVGVNCRLGPYHMIQALEEVPLPEKAVLSAYPNASLPGFQDGRLV
YSTEPGYFQKSAQALYEQGARLIGGCCGTTPEHIEAIAAKVKGKKPIVEKEVPVQQPAAI
EVAERENRNPHLHELATQGRSIIVELDPPKRLNTDRFLEGAKALQEAGVDSVTLADNSLA
SPRISNSAMASIIQSRYGINPLVHIACRDRNLVGLQSHLMGLHTLGITEVLAVTGDPTKI
GDFPGATSVYDLSSFDLIHYIKQLNKGISFSGKSLGQSTSFSVAAAFNPNVRNLNRAVKR
LERKLSYGADYFISQPVFNQEQIIEVYEATKHISAPIYIGIMPLTSLRNAEFLHNEVPGM
SLSPEILERMENVSTDRDKAQAEGIAIAKSLIDTALDLFNGIYLITPFLRYEMTVELTQY
IQEQTKERQERKVTDGIHII
>A0A316D3E6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanotoga teriensis|TrEMBL
MFIKDKFINKKPIISFEIFPPKKTGSIKKIYKTIEELAVLTPDYISVTYGAGGSEHDKTT
EIASIIKNKYNIESLAHLTCINSNKKDIYNTLNNLENENIENILALKGDIHPDYKLKKDF
NHASDLIEYIKENFNFCIGSAVYPEGHLEALNKSMDLFYTQEKINKGTDFLISQLFFKNK
IFYEYQEKLKNRNIKVPLQAGIMPVVNKKQVEKIVSLCGTYMPEKFIKVMNKYENNKEAL
LDAGVTYACDQIIDLLSSDVDGIHLYVMNNPITARKIVERIKNILKYLGENNG
>A0A1G2Y2B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium GWF2_42_9|TrEMBL
MTELNKLLDKQIVFGDGAMGTMLYSKGVFINTCFEELNLTNPQLVGQIHEMYVSAGSNFI
ETNTYGANELHLARFGLAEKTAQINTEAVKIAKQASAGKALIAGSIGPLGVKITQAGLIS
EKDISSAFTNQISALYQAGADFLLFETFHSLKDLLTAIVCASKICNLAIIAQMAVNDQNE
TLYGDKIDYALAKVAEFEQVAAVGLNCSIGPAEMLEVLPLIKNATSKPIALQPNAGLPQN
IDGRTVYMCTPEYMAEYAKRFYEKGVKIIGGCCGTTPAHIKEMVKTVRPLHKADLSSAVI
ELRSPEPTHISLQKPVELKDKSKFGAKLVSGEKIYSVEISPPKGTNVSALIEKVKLCQQH
GIDAVNIPDGPRASSRLSAMITAIKINQLCPNIETILHFCCRDRNIIAMQSDLLGIQAVD
LKNVLIITGDPPKLGEYPDATAVFDLDSIALTKVVSNLNRGLDIAGNNLPSKTALVTGVG
ANPVASDLDREILRYKKKVEAGAEFSITQPVFDEKSLFKFLELTNDCKIPVIAGIWPFTS
YKNAEFMANEVPGVVVPSEILHRMSKTKDQQDGKRTGVQIAMELMDKIKDVVAGYAISAP
FGNVNMALACAGKIGIDKI
>A0A890VY01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bos grunniens x Bos taurus|TrEMBL
MGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITGHL
NKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKGHP
EGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCPILPGIFPIQGY
HSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYT
LNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQEWD
EFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHYLSGE
PNQNGYKVTCLPWNDEPLAAETSLMKESC
>B7GLS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus flavithermus (strain DSM 21510 / WK1)|TrEMBL
MDVGLLDDLKERIVIADGAMGTLLYAHGIDRCFEELNVTKPEEIVHIHEAYIDAGAEIIQ
TNTYGANYVKLARYGLQDDVKKINEAAVSLAKQAAKGRAYVLGTIGGLRSTNKSTISLEE
VKRTFREQLYVLLNENVDGLLLETYYDFEELQTVLSIARQETTLPIIAHVTLHDIGVLQH
GMPLAEALRQLEQLGADVVGLNCHLGPYHMLRSLEEVPIPSRAFLSVYPNASLPQYRDGR
FVYETSEQYFEETARAFRDQGVRLIGGCCGTTPKHIAAIARALSDRTPVYKKEVKQRHTI
IIQEEKQTTAPSLADIARMRRSIIVELDPPKKLGLTKFLEGAKALKEAHIDALTLADNSL
ATPRISNVAVGTIVKQQLNMRPLIHITCRDRNLIGLQSHLMGLHTLGMTDVLALTGDPSK
VGDFPGATSVYDLSSFDLISLIRQFNEGLSYSGKPLGQKTNFSIAAAFNPNVRHLDKAVK
RLEKKIECGAHYFLTQPLYSEKQMEDVYEATKHLSTPIYIGIMPLTSARNADFLHHEVPG
ITLSDDIRARMAACANDPIQATKEGLAIAKSLIDAAFDLFQGIYLITPFLRYDMTVELVR
YIHEKERLAKERTVYYG
>A0A842F6N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria booriae|TrEMBL
MNLRRDLSEKVLIADGAMGTLLYSYGVDRSFEELNLSHPDDIVAIHRAYIEAGADIIQTN
TYSANYIKLSRYGLQDDIKKINQAAVRHAKEAARGTGVYIFGTIGGINGANDARISAPSM
EEIKRSFREQLYCLLLEGVDAILLETYYDLDELKTVLKITRETTDLPIIANVSMHEPGLL
QSGQTLASALQELADLGADVVGGNCRLGPYHMAKALESVPILENAYLSAYPNASLPQMDE
GKVVYQTETDYFEQYGEIFRQEGVRLIGGCCGTTPDHIRALRKGLKLLEPVTSKVVHPIL
ELAELESAEDVGVRLTDKVKETFTVLVELDPPRTFDTDTFFEGAKALDDAGVDAITISDN
SLATPRISNMALAAILKQEYNIRPLIHLTTRDHNLIGMHSHIMGFHKLGILDVLAVTGDP
SKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFQVAAAFNPNVLKLDKA
VRLIERKVEYGADYIITQPIYDTEKAVQLKEALDAAGITVPIFVGVMPLLSSRNAEFLHN
EVPGIRLTDEVRERMREAEQAGTAREEGMAIAKEIIDAICKHFNGVYIITPFLRYDLSIE
LTKYVQSKQEVAEQIISQN
>A0A662P5H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermococci archaeon|TrEMBL
FFKELGPVDVPILVGIFPARTFGQADFFDKFVAGVDVPPDYLENMRATKQIKDKEKRKEE
VDRVNVEFFTGFLEHLKGTPAAGCHMMAVGYPRVIPALKKIME
>A0A2K3Z9Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus felis|TrEMBL
MSRLLETLKHNVLVADGAMGTILYSEGLDTCPESYNLTHPEKVERIHKSYVDAGANVIQT
NTYGANFEKLKPFGLEHKVKAIHEAAVAIAKRAANEDTFVLGTVGGFRGVQQGELSLSAI
QYHTEIQIDTLVSSGVDGLLFETYYDLKELLGAVTLARKKYDIPIIAQLTASNTNYLIDG
TLINDALSQVIEVGANIVGLNCHHGPHHMKNTFSHIEIPNHAYLSCYPNASLLDIDHNHF
KYSENAEYFGNIAEQLIEEGVRLIGGCCGTTPEHIRKIKDAVTGLKPITDKKVIPIHKKR
ERTKKEPHSLNLAERAKKQPTIIVELDTPKHLDTKRFFENVKALDDAKIDAVTLADNSLA
TVRVSNIAAASLIKQRFDIEPLVHITCRDRNLIGLQSHLLGLSLLGINEILAITGDPSKI
GHLPGATNVYDVNSKGLTELALKFNEGINTDGDALKAETNFNIAGGFDPHVRNINAAVRK
METKIESGMHYFITQPIFTKEKIIEIYEATKHLDVPIFIGVMPITSYKNAQFLHNEVPGI
KMSDDVLVQFKAVAGDREATYQLSVSLCKSLIDTVHQYFNGLYLITPFERVDYSLELAAY
SKSITDNNQEVIL
>A0A1G2YK91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium GWF2_42_9|TrEMBL
MQANGRKRLSQTLLKKDGFVIVAELVGGPNFNYTPIQKFLTAYNSSGGKDIPQGFNFVGI
ASPQSPGGVANIEPADVNRYLTTQNLLGDLDFIPHISCKDANADALTSLLAAHKAAGVES
VLALTGDKPVSSKGVFELESTGLLAKITRINNEAYLSAKVETLAQTKQFFAGAAVSPFKY
TEASQMQQYYKMEKKIACGAKFLITQVGWDWKKSLELVRYLKENNIDIPVIGNVYLLSTI
TPAPRLMHDIKLPGCFVSDELLAKVYSETVDQHIERAAQQIAMYKAIGAAGVDVGGVHDY
EMFIKILKRAAQIGTNWEQYKNNLCWPPIKAFYLYNDAGNRTQQSMYLKTANHRVFNFMH
RAILDPKHNGFHAFKKTLEFFGAKKGKGFAYKGFFMLEKPMKYCMFDCEECGDCYLPENF
GLCTIGGCEKGMDNAPCGDSTVEGKCGNNLERICIGDRIYKAAGAEKGGYEKLRKTINKP
RIPALEHSASIPNYLFSRDHTMKNAIINIGEAIHASIPKTGQIMQQLLALGDDCFNKPSP
EFEYIKALIESQAADGADYIAVNIDQFGESDPSLAVRLMKEYVKLVRKYSRGVPVCVDSS
DDNVLIAGLKEWYDTTEKVQPPLINSIKIYTIDNMMPLKKHYDYKFIGLLISEAKATTDN
VDDLYNLAKTIYNAAMKHGFKAEEIFFDSTVFPLAIDMPMQPGVPGYTYRTFNTIKKIKT
DPQLKNCHFSLGVTNSVRDLPARKIGVTRAYVEVAMRYGLDASIVNASHHLGNSPADADL
VKLVEAYADLDGSSEKLNVAMQLMGEFCQKNRKPTN
>A0A1C4NQ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SolWspMP-5a-2|TrEMBL
MALGIPSTRPDRAATIRDLLASGHRSYSFEFMPPRSAEAEVGLWTAIRRLEALSPTFVSV
TYGAGGSTRGRTVNVTGRIAQETTLTPVAHLTAVDHSVSELRNILGHYADQGVRNILALR
GDPPGDVLGPWTRHPEGIEYAAELVRLIKESGDFCVGVAAFPEMHPRSAGWDDEIRHFVD
KCRAGADYAITQMFFDVDTYLRFRDRVAAAGCATPIIPEIMPVTTIRSLRRVPGLSTAAF
PPALAERMLAARDDPKTVRALGIEHATAMCRRLIDEEAPGLHFMTMNFSKVTTEIYRTLG
LHPA
>A0A3C0GZ73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium|TrEMBL
GANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>X5S4D0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSJC265A00|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFRTFMQRARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDEIIKRLEGAQDQKKEGKQLCTDIINEVKEIPGVSG
IHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRHDDQMVADRLESILHDDITETQVDMVK
TAH
>A0A1H7DG99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia diazotrophica|TrEMBL
MNPIELSFEFFPPKTQEGLDKLRATRAQLLPLKPKFVSVTFGAGGSTQQGTLDTVLEMGK
DGVDAAPHLSCIGSSKESLRAILNEYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEFGDWFRIEVAAYPEYHPQSRSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DAHKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVAKRLESFGDDRDAIRAFGLDV
VTDLCRRLVDAKVPGLHFYTLNGAAASKAICGRLGF
>A0A8H7QXX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor saturninus|TrEMBL
MKVIDKIHKAEEEGRTFWSFEYFPPKTEMGVQNLYDRMERMQRFGPEFVDVTWGAGGTSA
DLTMDIVATSQSVYGLETMMHLTCTNMPVEKIDTALKNAKACGCQNILALRGDPPKGQLN
WESCENGFNYAIDLVRYIKEKYGDYFCIAVAGHPEGHIDNQNKEDDLLRLKEKVDAGADL
IVTQLFFDVDVFIQFVKRCRDIGITCPILPGIFPIQSYAGLSRVISFNNNHVPQHIWDDL
EPIKEDDQAVKDYGIDLAVEYIQKIKKETGIIGFHIYTFNLERSSRLILEKLGLVPEQEH
VKPLPWNQSLGPKRTKETVRPIFWKNRAQSYIQRTESWDEFPNGRWGDARSPAFGEFDRW
GVSIKYPIEKRKSMWGEPQSPDDIALLFARYCKGKLEGLPWSAQKLEPETDTIKQRLAAI
NLLGYLTINSQPAVNGAKSSDHVYGWGPKNGYVYQKAYLEFFIPQQKLDELISKIGNDPE
VTYFAVNKDGDLKTNTIDDEPNAVTWGVFPGKEIVQPTIVEPIAFMAWKDEAFGLWNEWA
RMYDRQSLAAEVIVGIYNNWYLVNIVHNDFQDESGIWRLFDLEIDGDLSKKLRRASGTL
>I3ZIA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terriglobus roseus (strain DSM 18391 / NRRL B-41598 / KBS 63)|TrEMBL
MSETKTQPQTHDVERLFGPAPVLCDGAMGTMFYARGIFINRCFDELNLTDPQMVRDLHEE
YLVAGAEVIETNTFGANAVRLKRFGLEGKVAEINTAAVRIARAAVDGVREKHAHQAFVAG
ALGSLGFDKKDADPAMMLAAYREQVDALVAAGVDLFVVETVTSMAQAKAAIQAARDAAPD
LPVIAMVTVTDAGIVADGTSPEDAARLFEEWGARAVGCNCSDGPMQVLDTIERMRKVTKL
PIAAMPNAGLPNCVDGRSIYLSSPEYLASFARKAMRLGATLIGGCCGTTPKHIKAMRSSV
KAIQAQAEGVLSAGAKPTASEIAPPPLAERSLIGARIARGEFVSMVEIVPPKGIDATREL
EGARMLKQLGVHAINVPDSPRASTRMSAGSMCLQIEQKVGIEAVIHYTCRDRNLLGIQSD
LLGASSLGLRNILCLTGDPPKMGSYPDATAVFDVDAVGLTRIVRDMNHGLDIGGASIGSS
TGFVIAVAANPGVPDLDAEVRRFAAKVEAGAEFGITQPVFDMRLLETFLKRIEGFRIPIV
AGIWPLTSVKNAEFMKNDLKVSMPDEILSRMAANAASPEHSRAEGIRIAQEMLAEAQGMV
QGVQVSAPFARYAAAAEVLEAML
>A0A2H5XA98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR17|TrEMBL
MPAERGRQLLERLREQIVIGDGAMGTELWRRGLPQGLLPEQANLTAPELVRRIHYDYLAA
GAQIATTNTFGANPLRLTPLGLDKKLDDIVATAVRLAREAVAERHADAFIAGSVGPVGRL
KDPLELTDDDLDNAYRALILALADAGVDVLLLETFVDLSDLRRAVKIAKQTTDLPVIAQL
AALDEGGRGTEGRAALAVFELEKLGIDGIGTNCGVSPTRNLSVVQALARLTDLPITAFPN
LGYAQYVDGRFVYLGNPDEFAGLGEELWRLGANLIGGCCGTTPEHIRLLAERLKSKTPQP
RITRRIEVKPEEQPKLKSPMPNFLSKVGSEPVVIVELDPPRGLDYEPIVEGAKLLARAGV
DAISIGDNSLASIRLSNLVMALLIQRETGLPTICHFAGRDHNLIGAQSLLMGMAVLGIPA
VLAVTGDPARLAPDVGASSVYDLNSFQIIELLSKLNRGVNWVDAPIGKRTDFLIGAGFNP
NVPNLAAEVKRLKRKVEKGAQFALTQAVFDPDRIKACGQVMQEVGIPIFVGIGILISARN
AAFWKTVPGVRMPDTLLQRMEKAPKDKQLTEGIAIAQELIEIALRHCPGVFLVPPFSRAE
YALPLVEFVRNGGEIAWLSHQAVSEGN
>A0A7W2R161|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas juntendi|TrEMBL
MSLLKTALREHHFVCVMEFVPKASAERFAALQAIMDRAQLCGWPMTVAIGDRVGSPLDMS
PLDALASFDRPVPALPHFSGKDRERHHLLAQLQRMEAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQAAPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMREMLEAETAQSK
AFAQSRSVDRLALQIIGTKLMGYAGVHLSGIHDLKQLLALEARLAYWQTHVHTLEQWAPA
WQASWQMPGLPAVTFHPPQANWRQGESRVDASFKEKARYHLMHGMHGLLFSRRNSLSKAF
GWAVRQPLWTTRLGAQVLHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVGQTAVLRERLIPCIEEQTRHRSSWPQWFAPPSP
RRVSPQPAPRTQPES
>A0A7W2JNQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas juntendi|TrEMBL
MSLLKTALREHHFVCVMEFVPKASAERFAAMQAIMDRAQLCGWPMTVAIGDRVGSPLDMS
PLDALASFDRPVPALPHFSGKDRERHHLLAQLQRMEAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQAAPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMREMLEAETAQSK
AFAQSRSVDRLALQIIGTKLMGYAGVHLSGIHDLKQLLALEARLAYWQTHVHTLEQWAPA
WQASWQMPGLPAVTFHPPQANWRQGESRVDASFKEKARYHLMHGMHGLLFSRRNSLSKAF
GWAVRQPLWTTRLGAQALHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVGQTAVLRERLIPCIEEQTRHRSSWPQWFAPPSP
RRVSPQPAPRTQPES
>A0A2D4BYX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pythium insidiosum|TrEMBL
MGKIIDAILATYAGSSDGAASTSTSSSAGAGAARPTVSFEFFPAKTEDGVFNLLNRVEEM
GFSLRPTFVTLTWRSAFKDEKLWLRIGAHIQNEFQLDVLLHLTCHLPREELRRVLHAARA
AGIRNILALRGDPPIGAERWKPVPDGLNNAVDLIRLIREEHGDYFCIACAGYPEVHTESW
NHPDLPPSKEARLLDLQRLKMKQDAGADFIITQFFFDTDNLLQWVKDCRELGISIPILPG
YLPIQNYNSFLKFTSWCKTRVPHDVLAALDKIKNDDAAVRRYGTELAIQTCKKILDAGIK
SLHFYTMNLASTVTAVLDGLELIPARAQRDLPWQSTLRRTNSNGDRTEQVRPIFWSNRQA
SYIARTSAWDEFPNGRWGDRASPAYGDLSEYYLAFKRPKVNRRELWGSPQSHEDVWQVFV
RFIDGAVKQLPWCEQALSLESVVIKENLKWINAHGFLTINSQPRVXGAPSTDPSVGWGSP
NGXVFQKAYLEFFVSPRLLEKLLVAVKDYPXLSFHAMNRQGVEYTNAPPHSVTAVTWGVF
PGQEIVQPTVVDSDSFEAWKDEAFELWQTQWASAYDPTSTAFQVVQDVXNSYFLVNVVDN
DYTNDESDIFSIFTRIITDDMSKQDLRDRVIELEAKNEKLHETIAKFQTLHDELSQDLRD
THQQLASARDETQQLKTQLRQLQAQLALSTL
>A0A0T6ARL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium CSP1-3|TrEMBL
MTLREALSSGRFVVTAEAQPPKGTAVDEALQQAERLRGRVAAFNVTDQQSSVMRLGSLAL
CHLLVERGLEPIYQVTCRDRNRIALQSDLLSAAALGIENVLCLTGDHVSLGDHPQAKPVF
DLDAVTLLVAARELTQGHDLTGHELAGTPRFFLGAVVSPCAEPVEPQLFKMEKKVRAGAG
FFQTQAVFEAERFAAFMETARGFGVPVIAGVILLKSAKMARFMNQNIPGIRVPDDLIKQM
EGSKDKEGTSAEIAARLVRDLRGLAAGVHIMAMGWEHLIPRVLEFSGLPAPAEAA
>A0A0H3PME3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae (strain NTHi 3655)|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>R7E483|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Akkermansia sp. CAG:344|TrEMBL
MHLRERLQSGAGPSLSFEFFPPKNEQAAAALYQTIRELEPYHPSFVSVTYGAGGSTRELT
REVVLRIQHESRIPTVPHLTCVGHSREEVWSILDQYAQAGVRAVLALRGDPPRGTENYNR
DADAFRHAAELVAFIREYNESGRHPDPDGFAIGVAGFPEGHPSTPNRLREMDFLKAKVDA
GADYICTQLFFDNHSFLDYRERCLLAGIKVPILAGIMPVTSLSGMNRMAELSGGTCFPAR
LLKALKRAGSNPDAVQEVGIQYASSQCAELLDSGVDGIHFYTLNQSRATRQIYRNLGLKD
SLQLLEHGEDK
>A0A418SJ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudooceanicola algae|TrEMBL
MTTPAVSFEFFPPKNLEASFRLWDTVNVLAPLNPRFVSVTYGAGGTTRDLTRDAVATLHK
HMGLNTAAHLTCVNATKEETLAIADGFAEAGVTELVALRGDPPKGEGAFSVYPGGFANSV
DLVEALAQTGKFTIRVGAYPEPHPESAETAADVAYLARKFQAGADEALTQFFFETDTFLR
FRDACVKAGIDKPIVPGIMPIENWKGMQRFAKGCGANFPAWLAEAFEKADRDERADLLAT
ALCTEMCDKLLAEGVQDLHFYTLNKPELTRDVCHALGVTPQGKLENVA
>A0A8J7Z0J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxacorys almedinensis A|TrEMBL
MTNFRFAQSYGQAPLSAFRTAAEAGEFLITAEVAPPKGADPSHMLAMATMLKGRVHSVNI
TDGSRAVMRMSSLVSAALLLQQNIEPVYQVACRDRNCIALQADLMGAHALGIRNVLALTG
DPVKAGDHPTARGVFELESVRLLTMIRKLNGGLDWNDQPLTDGATDLFSGAAVDPQCGSW
SGLQKRFERKLEAGAQFFQSQLITDFDRLDKFMTEIANGAGKPILAGIFLLKSAKNARFI
NRAVPGVNIPESIIERLECASDPLLEGVAIAAEQVLLAKDLCQGVHMMAVKREDLIPQVL
DLAGIAPVGKPREVETAHHNSVSV
>A0A7Y5IZ05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MRIDQLLSRHKPSFSFEFFPPKDEEGFAQLYRTLETLKPLAPTFVSVTFGAGGGTRAKTV
DLVKRIKTEIGLEPMAHLTCVGMDRKQLSGILDELQSSGID
>A0A2W6W7K2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp|TrEMBL
MTFSLTQLEEARRALDAPLFADLSGDAQVSFEFFPPKTEKMEETLWNSIQTLSPLGPRFV
SVTYGAGGSTRERTHNTVARIAKETDLAAAAHLTCVAASKAEIAEVADAYWQAGVRHIVA
LRGDPPEAGTKFVPHPDGYAGAAELVEGLTRLHPFEISVAAYPETHPDAQSAQSDLDNLK
RKIDAGATRAITQFFFTPEAFFRFRDKAAAAGITAEIVPGIMPVSNFASTLRMAAMCNTE
VPSWMARLFEGLDDHPGARQLVAATLTAELCRKLYAGGVREFHFYTLNRAELSYAICHLL
GLRPKVGAELVA
>A0A2J6IX88|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
ANCGAGPRELLQALKRMATATPLPLSAFPNSGFPEYVDGRSIYLSTPEYFASRAKEMVDC
GASLVGGCCGTGPEHIAALVPLLSGATPTERSSRIDVLVEEHRPVVITTEKSSWLERDAI
PVTVELDPPRGTDCAAILAGAQRLVAAGVSAISVADNPLARIRMGNIALASRIQQETGAE
VIVHITGRDRNLIGLHSDLMGAHLLGIRNVLAVTGDPVSLSGEAGATSVFDVNSIGLLEL
LSNLNGGRTVYGQKLGEPTRFLLGAAFNPNARNLDGQVRKLERKIEAGARFVQTQPVYSA
EVIDAMLAAVNGKAPLLLGILPLVSERNAEFLHNEVPGIDLPDEVRHRMRGKSGEDGLRE
GTAISREIIDAARGRVDGFYLMPPFGKVDLAVELLEYIRSL
>A0A4U5WP50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lasalocidi|TrEMBL
MDVVAPLPRPAAGDLLDGFSLEMTGKDVAALEAARPAIPDGTRVNVTFLGTEDTELRLAA
VRAVRRLGLVPVPHLSARRLRSRAELEAYLSALRDADAADHVFVVGGDPTVPLGPYDDAL
AVLRSGLLQEYGVRHVGVSGYPEGHPAISEPALWSAIEDKAAVLREEGLAGSVITQFGFD
TEPVLAWLEAVRARGVDLPVRVGVPGPAGIRRLLRYAARFGVGTSAGIAKKYGFSLTNLM
GTAGPDRFVHTLAERHDPGRHGELGLHFYTFGGVGATSDWAAAFRTGTHVPAPAPATA
>A0A1J4QB89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces malaysiense|TrEMBL
MALGTASTRTDRARTVRDMLAGGKTTYSFEFSAPKTPKGERNLWTALRRVEAVAPDFVSV
TYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVAHPKGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVAHFVD
KCRAGADYAITQMFFQPESYLRLRDRVAEAGCDTPVIPEILPVTSVRMLERLPKLSNARF
PDVLKERILAAKDDPAAVRSIGIDFATEFCARLLSEGVPGLHFITLNSSTATLEIYENLG
LHHPPQA
>K9YWU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dactylococcopsis salina PCC 8305|TrEMBL
MSRFRQAVEAQEFLVTAEVTPPKGGNPDRMLQVAQSLKGRVHAVNITDGSRAVLRMSSLA
ASVVLLRNDIEPVCQVACRDRNLIGIQSDLMGAQALGIRNILALTGDPVKAGDHPKAKAV
FNLESVRLLKLIQKLNEGTDFNDKPLTDGALDLFAGAAVDPQSDSWSGLQRRFEQKVKAG
AQFFQSQMLTDFDRLEKFMDEVASPAKKPILAGIFLFKSAKNARFIQKYVPGVHIPEEII
ERLDRASDPLQEGIKIAAEQVQTARQLCQGVHMMAVKKEEAIPSILDLAGVKPVEGVKLP
TAATR
>A0A5F0H0J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Hh38|TrEMBL
MSACNARPAFSFEVYPPKSAAAASALMSTIDHLAAAGPEFISVTYGANGSSRNSSLDVLR
YIKDHTEADAMAHLTCVGSSHAGASRLIREFLDAGIRSFLAIRGDAPQGAVEGDNTFLGD
LHSAGELVQLIHRVQTERVPYIETVIPGLPGARGVKTERSKVRIGVAAFPNGHPNSRSVS
QDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLFPILPGIMPVTSPNRLRRI
LQLSGEKLPADLSIDLEVEPTEEGQRQIGIDYAVRLGQDVFAGGAPGLHLYAFNQHDTVL
QVLEGCGALPVPAVML
>A0A2N6DX97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MSDFSRQLAAGAFVVTAEIAPPKGTAIEPCLEVAKAFRGITAINVTDNQGANMRMAALAL
AIKLKELGLEPVLQITCRDRNRLALQSDLLGAAALGVENLLILSGDHSRFGDHPDARPVF
DIDSVQLLDTVARLASGSDMSGHTLDGCPCFFPGAAVNPAAEPFDLMFQKVRKKVASGAR
FFQTQAIFEREALARFMDAMQPLQTPVLAGVLLLRSARMARFLNQHIPGVRVPQAMVDRL
DIASDPAAEGLSMAREAVRWARDLCQGVHLMTLGHEGQIPEILA
>A0A2N6ED16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuromonas sp|TrEMBL
MNRISIELVPRNRETLIRDMELVHHHFPAIDILNIPDLLKFSLRSWEACQLARPWFSQSI
AHLRAIDFDARQPEKLLDILHHCEISQVLVINGDQPQDMSRRVYRTSSVELIRTLKRERP
DLTVYAGIDPYRSGIKAELDYVRRKQDAGADGFFTQPFFDMRLLEIFHGLIGDLDIFWGV
SPVMSERSKDYWDNLNNAIFPPDFAPTLAWNRNFARQALEFCKSHETNIYFMPIRIDITD
YLEGII
>A0A2M8JUV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sediminibacterium sp. FEMGT703S|TrEMBL
MKVTEHIQQSKDTLISFEVLPPLKGKTIQHVFDHLNPLMEFKPSWINVTYHRSETAFKKK
VDGTFEKVEVRKRPGTVGICAAIMNHYRIDTVPHFICGGFNKRESEDALIDLNFLGIDNV
LVLRGDAAKNEASFEPETDGHKFAIDLQKQVVNLNSGIYLDEDIQNGGKTNFCIGTAGYP
EKHFEAPNLEIDLQRLKDKVDAGADYIMTQMFFDNQKFYDYVKACRDMGITVPIIPGLKP
ITNKKQLSVLPRIFHVDIPTDLSNAISKCKTDADCEQVGTEWLIQQSKELKAFGVPVLHY
YTLGKPKVIWNVVNAVY
>A0A3D2AMM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oceanospirillaceae bacterium|TrEMBL
MLPPIHLGHNHLLSCFMTPRYSFEYFPPKSNPTTLALDTCISALKVWQPEFCSMTYGAGG
SSQNESFNAIQRLQRNGMEVAAHITAVGATKAEVNAAAQQFVAAGVNHLVALRGDSPEGE
FVPHPQGFQFGTDLVAGLRQWFDGIISVAGYPETHPQASSESADLRHLASKVDAGASQIM
TQYCYDTDQLLRFVDQTQQQGIEVPIVVGVMPIHDIVAIQRFSARCGASVPRSIVEQFEA
LQDADDQYQLSVDIAVKQIQRLHENGLNRVHLYTLNRPQWVQGILQALAQPALAESA
>A0A496RTV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Omnitrophica bacterium|TrEMBL
MGFREKIGKGEFVITTELTPPCGVNIDSVLRSAEFLKNKVDAINVTDMAGGIMRLGSLSL
SHLIKEKGGEPIFQITGAHRNRLALQSEILSASVLGIENVLCLSGDPPLEKGEKPAKPVF
DLDSVGILKMIKRMEEGYDLSGRALEGRVRFFCGAAVDPNAENIEFQIEKMKRKIEAGAR
FFQTQPVFNLDKFKRFMEKAGKLEVPILAGIIFLKNRKSAEYLNRNILGISIPAEMIRRI
EEAKEKEKESVEIAWELIRDLRGLCQGIHLMPLGKNELVNQLIEKMKRNGNLAGAPI
>A0A7V3UWV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ignavibacteria bacterium|TrEMBL
MKSFRERLENEIIVFDGGTGTYLYEKGVFINRCFEELNLTNPELVKQVHRDYLLAGADVI
ETNTFGANRFKLAPHGLNEKIYDINYAGAKLAREVAGDKILVAGSVGPLGVQIEPLGKIG
YDEAKDYFKEQIQPLIDGGVDLIILETFTLAEELIQAIRAAREINPDIPIIAQVTVNEEG
NLVSGEPLEKFVELVSQYKPDVIGFNCSVGPKPMLDALEKLRSLTDLPISVQPNAGYPVN
IGGRNIYMTSPEYIAEYSKRFIQTGANIVGGCCGTNPSHIKAIRRAVQALQPSKRLDIKV
EELKIEQPSNVRVYEKYEKSRLSNKLLREEFVTLVEIVSPRGVSAQKEIEKARKLYHFGI
DAINIPDGPRAMARMSALAMAVLIQREVGIETVLHFACRDRNVIGMQSDLLGAWALGIRN
ILAITGDPPKLGNYPDATAVFDVDSIGLVNLLNRLNHGLDLAGNPIGEATGFSIGVGVNP
GAINLDEELRRLDWKVQAGAEYMITQPVFDISLLENFMKRVEHYKIPLIVGIWPLVSYRN
AEFMNNEVPGARVPDNIMERMRKAQEISKEAAFEEGIKIAKETYDYIRSEVSGVQIAAPL
GRIEAVFKMLSDEEFYTM
>A0A8C7ASH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Neovison vison|TrEMBL
MDHPTPKVLPSRSRGPSLGPWTLEAGRVRFSVPPSISRNLAMVNKPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQGQITD
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYATDLVRHIRSEFGDYFDICVAGYPKG
HPDAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDDAIRNYGIEQAVSLCQELLASGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFAHYLS
GEPNQHGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPSQQDAQAL
>A0A3N7G5W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Populus trichocarpa|TrEMBL
MKVIDKIRAAAAAGDSNGGDSSSNNKVVFSFEFFPPKTDDGVDNLFERMDRMVSHNPSFC
DITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLA
LRGDPPHGQDKFVQIQGGLACALDLVKHIRSKYGDYFGITVAGYPEAHPDVIGSDGFATL
EDYHKDLAYLKQKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKG
FIRMAGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNM
EKSALAILMNLGLIEESKITRPLPWRPPTNVFRVKEDVRPIFWLIVQRAT
>A0A8D4RDX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Haemophilus influenzae|TrEMBL
MSYAKEIDTLNQHIADFNKKINVSFEFFPPKNEKMETLLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEP
KGYAKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIENYLRFRDRCASIGIETEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGL
DDDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGVRP
>A0A285X7U2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinimicrobium sediminis|TrEMBL
MKITEHIERAGGRTLFSFEILPPLKGHNVQGIFDGIDPLMEFRPPFIDVTYHREEYVFIE
REKGLLEKRVVRKRPGTVGICAAIQSKYKVDAVPHILCGGFSKEDTENFLIDLDFLEIQN
VMALRGDAVKSEVYFKPEADGHRYACDLVKQVSEMNEGNFLDEALENGHKTEFCIGVAGY
PEKHMEAPSLDRDIQYLKSKQEAGAEYVVTQMFFDNSRFFEFVEKCRKSGIHIPIIPGLK
PISIKKHLSLIPHRFHVDLPCDLVREVEKCSSNNEVQEVGIEWCIQQSRELVAAGVPVLH
YYSMGKSENIRRIASEVF
>A0A2D8XLM0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parvibaculum sp|TrEMBL
MSSLGDRFRGRDNVRVSFEFSPPKTSEAEEKLWAAIERLAPLQPAFVSVTYGAGGSTRER
THATVKRMVNETDLKPAAHLTCVGASKAEVDGVIQGYWDAGVRHIVAIRGDMPDMEGPYK
AHEDGYLSTADLVRGIKAIGDFEVTVSIYPERHPESVSFDHDIDLLKAKIDQGATRAIAQ
FAFETEHYEHLLERVRKAGIDIPIIPGIMPTTNFKGVVRMAERCGATIPNWLAAYYDGLD
DDLPTRRLIAATVAAEQVHDLERLGFRDFHLYTLNQADLTYAICHILGYKPVAVS
>C1G7L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccidioides brasiliensis (strain Pb18)|TrEMBL
MHIKDKLAYAEATGHPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPSEKVDAALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIRDKYGNHFDIGVAGYPEGCEDQDDPELLMQHLKEKVDAGGTF
IITQMFYDVDNFLAWVKKCRDKGIKVPIIPGIMPIHTYAAFIRRSNWTKIQIPPGWLEAL
EPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVLDELGLIPSHETP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIQLWGKPKSLKELSEIFIRFLNGKLDRLPWSEGAVTEETDIIKRDLLD
LNSRGFLTINSQPAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNA
DLTYYCVNKTGELRTNTTDSPNAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHPASSPSRRLIQQVMDTWYLVNIVNNDFHRTHDIFDLFKNLKVKDLDLEVEPTYPAAE
FVGNIDHNGQSPEKLANGSAESKLQTITH
>A0A0N8K625|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium HLUCCO07|TrEMBL
MSLLNFRRKDTTAGAASPVNPQLEAFLAGYSIEVMPRTAEKVEDFRDLLPSGTRIYIAHI
EGTPIEDMVATAARLARDGYPVMPHFPARIIRDAATLENWIAMYQGEAGVDQALLLAGGV
DKPLGDFHSSMQLLETGLFDKAGFKRLHVAGHPEGNRDIDPDGSMKNVEEAIHWKQKFSE
RTDAKMAIATQFAFEAAPIVQWADGLKAAGITLPIHIGIAGPAKLQTMIKFAVTCGVGPS
IRVLQRRARDVSKLLLPYEPTEVLTDLAAHKAANPDSLIEQVHFFPLGGIKTNAQWAIEN
GGASATPASQQEQG
>A0A1M4WB91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schwartzia succinivorans DSM 10502|TrEMBL
MKRLSIELVPRSVEGLKEDLSMLKKLDLNIDVINIPDLLRFETRSWEGAAAAQEFYPAAI
PHIRAMDIDLTKPLPMAKFFKEKHIHEVLVIEGDPPQDMKHTVYPTVTTDVIRKFREELP
GIRVYAGIDQYRGSMQQEEYRIRRKLQAGAAGFFTQPFYDMRFLEMYQDMLDGLEVYWGV
SPIQSERSQSYWELKNHVVFPKKFVPTLDWSIDFGRRVVENADKMNSSVYIMPIKGNLEE
YLNGIFH
>B8LKP0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Picea sitchensis|TrEMBL
MKVIEKIQNAEKEGKVVFSFEFFPPKTEEGVENLFDRMDRMVEHQPSFCDITWGAGGSTA
DLTLDISNKMQNMICVESMMHLTCTNMPVEKIDHALATIKANGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDMIKNEVGATEEDYQKDLAYLK
LKVDAGADLIITQLFYDTDIYLKFVNDCRQIGIKCPIVPGIMPINNYKGFIRMAGFCKTK
IPSEITAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTLHLYTLNMEKSALGILANL
GLIDMTKIRRPLPWRPATNVLRTKENVRPIFWANRPRSYISRTIGWEQFPNGRWGDARSP
AYGALNDYQFLRRRSRSKKILEEWVVPLSSIVDIQEKFANFCVGKLKSNPWSELDGLQPE
TVKINEKLEQLNRKGFLTINSQPAVNGEKSDSPSIGWGGAAGYVYQKAYVEFFCSPEKLN
ELVEKAKNLPFVTYIAVNKKGATAANIGPTDVNAVTWGVFPAKEVIQPTVVDPVSFMVWK
DEAFQAWEQEWASLYPDGDPSRKILEEVQNSYYLVSVVDNDYIHGDLFSVFEEL
>A0A2H0AID7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium CG23_combo_of_CG06-09_8_20_14_all_51_20|TrEMBL
MPLKEKIEAGGFAVLAELEPPKGADFHSLLANADLVKGRVDAFMVPEMANSVVKASSLGG
CAFLQNRGFETVLQVCCRDRNRLALQADILAAGAIGIKTVMVVQGDDITFGDHHQARAVN
DVTLMQLLEAIAGLKNGKDMAGIELKGAPDFFVGSTFNAGAAGGALDLEIEELKKKKGLG
AAFVVTTPVFDTDIFEKLLVKLKPVGVSVIPTVLLLKSAGMARYIDRNVKNIFIPSQLIE
SIQKAPDKPVECVSIAGKLISRFKEMGAPGVLVSTIGWEEKLPQVLDEARL
>A0A2T3WBQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deinococcus arcticus|TrEMBL
MTRVSVELVPRSRSGLRAELAEVAAHLRGVDTINVPDLTRYSLRSWAGCGFARPGFAAIP
HLRAVDFNPREPLPFLPLLAQHGIEEVLVITGDAPADMSARVYDVDAVDLIRRLGREAPH
LRVYAGLDPYRQSFVRERDYLERKMDAGACGFFTQPFFDLRVADTWADLLPEGTPVWWGA
TSILTEASFNYWRARNHAVFPRTFAPTLDSNRAFAAELLQFARQRGQHAYFMPVKVNVLD
YLGGLLAGHQAPPTQALPRQNAV
>A0A085Z2Z8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium formosense|TrEMBL
MKITDHIKNANGKTLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEPTQGGHASAMDLVHQINDLGRGKYLHNQDEECEEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKFIEFVTKAREMGITVPIIPGI
KPIATKKHLKILPQIFKIDLPEDLINEVEKAKNNEAVKQIGIEWAINQCRELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>E3PB73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli O78:H11 (strain H10407 / ETEC)|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A353PTF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Treponema sp|TrEMBL
FQDNPGAMMQAGIAYATEQIIDLIANGIRGVHIYSMNKPDITAAIMHNISHIVEAVNAEA
HV
>A0A8E1ZRB6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. SwsAc2|TrEMBL
MSKKVPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIAEFN
GKGTPVAPHLSCIGDDKARIAELLDIYKDQGIDRIVALRGDLPSGQVGLGELPYATDLVR
FIREHSGDHFKIEVAAYPEMHPQADSFDLDIQRFCDKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVLDLGLA
>A0A2T4MEM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus auricularis|TrEMBL
MSQFLTQLKDNILVADGAIGTLLYSEGIDTCPEAYNLTHPDKIEKIHRAYIEAGADVIQT
NTYGANFEKLKAFGLEHKIKQIHQAAVAIAKRAAKPETFILGTVGGFRNITQTKLELSTI
QYHTEVQVDTLVEAGVDALLFETYYDLEELTNIVKLTRQKYDIPIIAQLTASNTNYLKDG
QPINEAIQAVIDSGANIVGLNCHHGPHHMVHSFSHIELPKNAYLSCYPNASLLDIENDTI
QYSDNAQYFGQMAQKLINEGVRLIGGCCGTTPEHVHFIKESVKGLKPVSHKNVVPMTQRK
SKGTNNENRNNLTHLVKTRPTIIVELDTPKHLDTTTFFDNVKKLDEEGVDAITLADNALA
TVRIDNLAAASIIKQQYNIEPLVHVTCRDRNLIGLQSHLLGLSLIGVNEILAVTGDPSRM
GKLPGATNVYDVNSKGLTEIALRFNEGINTDGDALKKKTNFNIAAAFDPNVRKLEVAVKR
AEQKIKHGTNYFITQPVYSTDKIKEIYEATKHLDVPFFIGIMPITSYNNALFLHNEVPGI
KLSDEVLERFEALKGDKEQTKAYSLSLSQELIDTVHQYFNGLYLITPFQNVDITLELAQY
SKSNTSTKQEAIS
>A0A7L2SWF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pomatostomus ruficeps|TrEMBL
MVNETQHTCSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITAHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRSEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7W3SVJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fontibacillus solani|TrEMBL
MKPDLRKRWENEVLVGDGAMGTYLYQLGSPVGISCEELNLISPDVISDVHRRYIEAGSQL
LETNSFSANYYKLSKFGLEAQVEEINRAAVRIAREAAGSEGYVAGAVGSIRGGKRVNVSV
QEMGTYFEQQISALLTEGVDALLFETYYDLAEMRIAVGRARKLTQVPIIAQFAVDQVGRT
MDGYKISEAFSILQDEGVDVFGFNCHSGPKGIMSVMSGLKGPLNVPLSVFPNAGLADYVD
GEYVYGASPEYFGECALSFANLGARLIGGCCGTTPEHIAATASALQGYKAESLSQGKPLP
EVREAIVVNSDMAVKEANNASNGASSASGITELVKERHTIIVELDPPRDLDISKFMEGAA
ALKAAGVDALTLADNSLAVTRMSNMALGHLVLTELGLRPLVHIACRDRNLIGTQSHMMGF
DALGIDHVLAVTGDPARFGDLPGASSVYDLTSFEIIRMIKQLNEGVAFSGKPLKQKANFV
VGAAFNPNVKHLNKAVERLEKKIASGADYIMTQPVYDPELIVAIKEATAHLDIPVFIGIM
PLASGKNAEYLHNEVPGIQLSETVRKRMEGLQGQQGRDMGVEIAKELLDTAMEHFNGIYL
MTPFMFYDMNVTLTNYVRERAKAMTPHLSHSS
>A0A723UD24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPSILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7I9V0D8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia crocea|TrEMBL
MGLAERIADRGDGVLLFSITPPRSSTTPEDAQRIADVTLARLEALDLDGLVLYDIDDESD
RNPAERPFPYLPTMDPAVFRDDFLARWRRPVVVYRCVGKYDEEAMERWLAEQDPATVLSV
FVGASSRDKERTLELPAAQKLRAEVNPGLKLGGVAIPERHARTGTEHHRMVAKQQAGVSF
FVTQVVYDVSAAKSMLSDYYYACREAEVEPVPVIFTLSVCGSMKTVEFLEWLGVDVPRWL
RNDLAHADDTLAVSFDQCLAAAAELTRFARRLGTPHGFNVESVSNRRREIEASVELAARL
RG
>A0A4R1KEW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Seleniivibrio woodruffii|TrEMBL
MKISEMLKNKRTVSFEFFPPKKEEGENVLYETIKELVDYKPDFVSVTYGAGGSTREKTVE
WTTHIKKNYGLTTMMHLTCVAADANSIDAITDAVDAINVKNLLALRGDYPADMPEEQRKG
EFRYAADLVGYLRKKHGDKYCLGVAGYPEKHPEASSMQSDIENMKRKLDAGGDFIITQLF
FDNDHYFRYMDILAKNGINAPVVAGIMPIINIAQVVKFTQMCGATVPQFLVEKMDGKSEK
NQFMTGVEYAVEQCRGLIDAGVAGLHFYTLNKHGATEAVLDRTL
>A0A327M697|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseicella frigidaeris|TrEMBL
MASLGSTLERWLTGPRVAMLPSPSSLPPPQLSFEFFPPRTAKLEADLWACIRRLEPLAPR
FVSVTYGAGGSTRARTHETVARLRHETSLTPAAHLTCVGATREEVDAVARAYWQAGVRHI
VALRGDPPAGAATYEPHPGGYAQAEDMVRGLRRIAAFDISVGAYPEGHPAALSPAADLDF
LRRKIDAGASRAITQYFFDTDVYLRFLDRCHAAGISVPIVPGIMPVTNFASVKRFSALCG
ASVPAWLERLFDGLDEDAETRRLVAATVAAEQVRTLQANGVDEFHFYTLNRPDLTYAIAH
ILGVRPQAAGTPGPEGPGADRQAGAP
>A0A318M3Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium asteroides|TrEMBL
MHEPIFSLEVFPPKRDAPVGTIYDTLDGLEGLMPDFISVTYGTGRRSDRTATARIAKTIH
VEYGIPAVAHLTAQYADHEVIDQALDMFDEAGVAAVLALRGDSVEGREPAGVFDHASDLA
AYIRSCRPNLSIYGACYPETHPEATSPQEDIKHLKIKVDAGVDHLVSQLFYDNADFLDFL
DRARAAGIQVPIEAGIMPITNEGQVRHMSEVCKARIPAAVESILERWGDDRASLREAGII
YASQQIADLVAHGVDGIHLYSMNHSGVTRRIWHNVRHLFRQVGTSSEPSSSKG
>A0A5C7SV87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera aminoaromatica|TrEMBL
MKPEISIEFFPPTTAEGAEKLHATREKLAALEPAFFSVTYGAGGSTRERTFATVKEIAAA
GHEAAPHLSCVGSSRDSIREILQEYAAAGIRRIVALRGDLPSGAGAAGEFRYASELVEFI
RSETGDRFRIEVAAYPEWHPQAKSPKDDLAAFKRKVEAGADSAITQYFYNLDAYLNFVDA
VRRMGVDVPIVPGIMPIGSFSKLARFSDACGAEIPRWMRKTFESYGDDSDAIRAFGLDVV
TRLCEKLLAAGAPGLHFYSMNMAGPTTEICRRLGLTA
>A0A1M6KJ95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Reichenbachiella agariperforans|TrEMBL
MKVTEHIKNANGKTLFSLEIIPPKKGENVQTIFNHLDPLMEFNPPFIDVTYHREEYVYKK
HPSGLLEKKTTRKRPGTVGICAAIRHRYDVDPVPHIICGGFSKEETENALIDLDFLGIDN
VLLLRGDAIKSEGKFIPQKDGNNYAIDLLHQVDGLNKGVYLDDSLDDPTPTDFCIGVAGY
PEKHFEAPNLEMDLDFLKQKVEAGAEYIVTQMFFDNEKYFEFVDHCREMGINVPIIPGLK
PIATKAQSTILPSIFHIDLPVELSEALQQCKDNKQAKEIGIEWGIKQSKELMERGVPVLH
YYSMGKSTSVQKIAEAVF
>A0A5R8VFW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter sp. NamB4|TrEMBL
MMFPVRIEVIPSEGIVEQVRALVPRTTALSVTCLPHHGIERTMRTAVELSDAGYAVVPHL
AARSIRTRAELTEIVRGCDAAGIREVFVIGGDRKQPAGGYDSALPVLEDIAQYSGGLMRA
GVAGYPEGHPLVSPVDLLDGLLAKQYLATHVVTQMCFSADKVHDYAALLRREGVNLPVWA
GVAGSVPRTKLVALATQIGVGSSLKFLSRKGPLARKLLSGDRYSPDSLITELGSQPGNLA
GIHLYSFNSLDSIPGLPNGKEPGHTSTTAALQPTSIRGAARDH
>A0A328R102|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinamargulisbacteria bacterium SCGC AG-343-K17|TrEMBL
MIYLELVPNNIPDLIKESKWALNSFKDIYGINVPDILRIDNRSYDAVTHLAKEAIPCIPH
IRICDFSIDNLLSLCNTLQDNNVDKILLISGDPPPNPLQPIFKHNIVNVIKTITSTMPKL
TIYAGHDPYRQSFKEEFNYSKKKLEAGAKGLFTQPIFDTNLTNILLDQCLPCEWFIGISP
VLTEKSFNYWVSRNNVVFPPDFKLSLDYNTKIAKEIITICKEKNQHNYIMPITCDIKPYL
SNICHEKNN
>A0A135P3L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium bohemicum|TrEMBL
MTKTDPDRHTSGNFKLSFEFFPPKNADMDVQLWETVEELARWNPDFVSVTYGAGGTTKAP
TLVAVDRMISVAGLSTASHLTCVDASKQEVHDVVEELRGIGVKHFVALRGDPATGPGTAY
KPHPDGYENAAALVRGLREIDDFQISVSAYPEKHPESESTDVDIDMLKRKADNGATRALT
QFFFDNTMFERYMERVTKAGITIPIVPGIMPIQNLTQLKRFAGRCGTSIPAFLDERFAGL
DDNPVERAKVAADVAAEQILDLQRHGISEFHLYTMNRAPLVNAVLENVGYRPLRQSAA
>A0A2E9DUD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Crocinitomicaceae bacterium|TrEMBL
MEFNPPFINVTYHREEYEYKKMGNGLLKKVSIRKRPGTVGICAALMNRYKVDAIPHIICG
GFTKEETESALIDLKFLGVDNILALRGDPMKNEAAFVPTEGGNAYALDLIGQISEMNNGQ
YLYEETKNSPSNFCIGTAGYPEKHFEAMNLSSDLKNLKKKVDAGAEFIVTQLFYDNEKFF
EFVSKCRDIGIDVPIIPGIKPITNLRHLSFIPKFFHVNFPEAFSNELEKCKNDEEVKQVG
IEWTTAQCKELVKADIPVIHFYTMGKGQAVKNIAKEIF
>A0A345IWK1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halarcobacter bivalviorum|TrEMBL
MLTDKIRNKENGILLYGITPPKINHTEEEIKEIAKKHVERISMLNVDGLVLYDIQDESDR
TDEKRPFPFIKTINPCEYSKNYLQELKTPRIVYRAVGNYTAKQFATWLESTKATQVHSVF
VGAASHEQQTNITLKEAYSIKKEVNDNLCLGGIAIPERHMKKHDEHLRVFSKQNSSCEYF
ITQCVYDVHAAKTFLTDYAKYAKENNIEPVPIIFTLTPCGSSKTLDFMKWLGINIPNYLE
EDLKESGDILTDSVKLSRDIFEDLFIYGKKRGIPVGCNIESVAIRKAEIDASVELLEEIR
EIINKNK
>A0A508A376|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces johnsonii|TrEMBL
MLDNEPTEPTAAIEGRNDDPGDAERATSRSLPTVSLELFPPRAGKAASATWGRIDRLLAT
GPDFVSVTYRPAFVTDPVPGSGEKGRWQQCDAPRVRAVQEESNPSEGVLAHVLGSSAVPL
MAHLTCIGYRKREAVDIITRFLRMGVRRFLALRGDPPTGTRADDVAGELRHADALVRVIR
EVEADYFGDGRRHVTIAVAAYPATNDHIEAIEVLASKQAAGADLAITQVFYDPADYVALT
NAASYAGVNIPILPGVIPLTDLGRLTRLEALTGVKVPDALRSSLGSASGATLVERGIGAT
LDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDAVDRGYLQAT
PGRGPSFLRCGSPGAAVSSRHPVQPHTTITKENA
>D2EPN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. M143|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQILDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A1E7GK81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacterales bacterium S3730MH5|TrEMBL
MKSGSNLERLLESGQFAVTAEAGPPKGTSSKVVQRKGELLKLCCDALNVTDNQTAIVRMS
SLSGCVLLKEMGVEPVLQMVVRDRNRLALQSDILGAAALGIRNVLCLSGDHQKFGNHPTA
KGVYDIDSIQFIQMVKAMRDEQKFLNGEDISGDVPFFIGAAANPFADPFEFRVTRLAKKV
RAGAGFIQTQGIFDMPKFVKWMKMVTDRGLDEKTHILAGLIPIKSVGMARYMRNNVSGLS
VPKEIIDRMADAKEPKEEGVKICLETIEQLKEVDGIHGIHIMAVAWEDIVSRIVEEAGLM
PRPVV
>A0A7C6D4F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
MYISEILRTAKPSLSFEVFPPKTDDTYGTVSQSVGELASLKPDFMSVTYGAGGGTSKNTV
RIARELQELHEMTALAHLSCVSSTREEIFAIMEQLRNANITNILALGGDRVARPDKESCP
DDYHYAYELVRDIKEVGSFCIGAACYPEGHIHSESQEEDMRYLANKVQYGVDFLISQMFF
DNDAFYKFIDRLQAAEICTPVLAGIMPVVSAKMIDRMLSLSGTKLTPRLQQLVEKWGDRP
EDMQKAGVDYASDQILDLVSNGVRGIHLYTMNRPEVARNIMENTKLTANR
>A0A240CA87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus muscae|TrEMBL
MSRLLNTLKHKVLVADGAMGTILYSEGLDTCPEAYNLTHPEKIEQIHRSYIQAGADVIQT
NTYGANFEKLKQFGLEHKVKAIHEAAVDIAKRAANDDTFILGTVGGFRGVKQGELSLSAI
LYHTEIQVDTLVNAGVDGLLFETYYDLEELLKVIKTTRARFTDIPIIAQLTASNTNYLIN
GTEINDALQQVTAAGANIVGLNCHHGPMHMKNSFSHIALPESAYLSCYPNASLLDIDNDT
IKYSNNAQYFGDTAEQLIQEGVRLIGGCCGTTPEHIRHIKASVASLKPINEKKVIPIHKQ
RERKKATSQRLTLAERVRQRPTIIVELDTPKHLDTTRFFDNIKALDEAKIDAVTLADNSL
ATVRVSNIAAASLIKQQFNIEPLVHITCRDRNFIGLQSHLLGLSLLGIHEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNRGINSNGDALKTETHFNIAGGFDPHVRNIKAAVR
KMETKIESGMHYFITQPVFTKEKITEIYEATKHLDVPIFIGIMPITSYKNALFLHNEVPG
IKMSEDVLAQFEAVADDKEATYELSLSLCKSLIDEVHHYFNGLYLITPFERVDYSLALAE
YSKSITNHNQEAIL
>A0A836DFW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salix suchowensis|TrEMBL
MKVIDKIRAAAAGGDANGSANGNGCDGSSNSKVVFSFEFFPPKTEDGVDNLFERMDRMVF
HNPSFCDITWGAGGSTADLTLDIANKMQNIICVETMMHLTCTNMPVEKIDQALETIKSNG
IQNVLALRGDPPHGQDKFVQIQGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDMIGS
DGFATLEDYHKDLAYLKQKVDAGADLIVTQLFYDTDVFLKFVNDCRQIGITCPIVPGIMP
INNYKGFIRMTGFCKTKIPAEVTAALEPIKDNEEAVRAYGIHLGTEMCKKILAHGIKTVH
LYTLNMEKSALAILMNLGLIEESKITRPLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRT
IGWDQYPHGRWGDSRNPSYGALSDYQFMRPRARGKKLLEEWAAPLKSVEDIYEKFKVYCL
GKLKSSPWSELDGLQPETKIINEHLGKINLKGFLTINSQPAVNGEKSDSPSVGWGRPGGY
VYQKAYLEFFCSKDKLNAIVDKCKSFPFVTYIAVNKGGSWISNVALTDVNAVTWGVFPAK
EIIQPTVVDPAASVCGRMRHLKSGQEDGLPCTQRVQSSYFLVSLVDNDYINGDIFAVFAD
L
>A0A1Y4WLF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavonifractor sp. An10|TrEMBL
MSKIAYTPEHPLLFDGAMGTLFAALPGRAGERCEGASLTHPGEISAIHRAYLEAGARAIK
TNTFGLGTELAQGNEALAGELIAAASRLALEAAAPYGALVFADLGPVPQDRQEDTGKLYI
RQAEHFLKAGVTHFLVETLSSDEGVAELAAWLEEHCPDAFLIASFAVGADGFTREGLPGR
ALLKRTAALPGVDGVGFNCMSGPHHLLSLVRGLKLEGTMLSVMPNAGYPTVLGRRTAYQG
TPDYFAQQMAQILRAGAAIVGGCCGTTPEHIARLARLLREEPAAPAAVVSGPVQAPARAP
AGTDRLWSKLERGEKAVAVELDPPANDDIAPFLSGVGTLRDAGADVITIADCPVGRPRAD
SCLLACKLKRELGVEPLPHMTCRDRNLNAIKALLLGLSMEDVHNVLLVTGDPVPSESRDE
VKSVFNFNSRKLARYVSSLGEDTFSTPFRLFGALNLNARNFDVQLRLAREKEDCGIRGFL
TQPVLSREALDNLKRAREVLKGRLLGGIFPVVSYRNACFLNNEVAGIRVCEEIIRLYRDK
SREEGEEIALTVSAAIAKEIAPFVDGFYLMTPFQRVGLIARLLDRFRADGLL
>A0A1M6MJE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicyclobacillus montanus|TrEMBL
MESNVWKAVPNVIGKDGQAFIVTDGAMSTFLHQIGLPLGVLPEQLNLENPEQVRSVHEAY
VNAGATLIQTNTFSASRFALSRVGIENQFFQIHLSAVNSARQAAASQAAVFGSIGALPVE
FIHENALSPERMEREYRRQIAEQAEALLQAGVDGFVLETFAESEWAYWALSAVRSLTNLP
IIVNLSPDEIGVTRDGMEIGHAFQWLQQAGADAVGLNCRLGPYGILRSYESLHLEKNGMY
AAIPNAGLLHFEEGKYAYTGNAEYFSKTMLDLAQHGVRILGGCCGTTPEHIQRLRKVLEE
TVFNESSTQSALSAGKGEKSGETSVSDLSETPKIEAKIELLSNRNQSLVEKVAQKRTVIV
ELDPPKTLDCSKFLRGASILAESGADFLTLADNSLGSIRVSNLALAALLKQRGIEPLVHI
ACRDRNLIGQQSHLMGLYVLDIHHILLVTGDPSRFGDLPGATSVFDVSSTELTRMVKRLN
GGIGFSGMSLEPASRFVIGTSFNPHVRNFDKAVERLRRKIEAGADYIMTQPVYDVKLIKR
LAEVAKDLTVPMFVGVMPLVSARNAQYLHHQVPGIQIPETILRLMDEAEPSQALHVGMDI
ARELVNSVLEHFRGIYLVTPFLRYSLTAELTRYAKSLNHRSISV
>A0A832ING0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Kryptonia bacterium|TrEMBL
MKKPFRERLKEGIIVCDGAMGTLLELYEYDEKPPEIHNLKNPDIVERVHREYIQAGAEII
ETNTFSGNRKRLEVYHLGNMVKEINESAVNIAKRAAGDAVYVAGAVGPTGKLLEPLGKMK
VSDAKEVFKEQIRILIESGVDLLILETFIDLNELDAAIDAAKEVSPEIPIIAQKTFSEDG
AILASNFPVEVVQHIKSKGVDVVGSNCTVGPQRMYGIIKSIYSGDVILSAQPAAGIPTLV
DGRSIYHATPEYLATYAKQLVEAGVTIVGACCGSTPSHIRAISEAVRGVKIPRKPLVVKK
TTTIEEESPKPEPSSRSNLAKKLGRDFITTVELDIPRGLDMSTVMEGARFCKENEIDAVN
ITDGARARIRMSSIAISHLIQKQIGIEAVTHLTTRDRNMIGLQAELLGAHALGLRNLLIV
TGDPAKIGDLPQAKSVFDIDSVGLIKIAKSMNMGRDSMGNTLGSSTSFLIACAANPAAED
FGYEIEKLYRKVESGAEVIFTQPVYKIEIFENFIKALEPLKIPVIVGILPLRSYRHAEFL
HHEIPGITIPESIQEKMFRARENASEIGIEISANLLKEMKTAIAGVYLLPPFKKYDVAIS
ILEKAGI
>A0A7X8JJU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridiaceae bacterium|TrEMBL
AARDADACERANVTNPELIRRIHQEYLAAGARLLRTNTFAAAALFGMSDPAGLKEVVSGG
LKLAGACAGNLAFVAADCGPAYNLAPETAVAAERIVIDTFLENDAELFIFETYADPDEFL
EHCKYIKNAKPSAVIIASFTLSPDGYTRKGLSISHLSNVMQACDLIDIWGFNCGVGPTHL
AEQLKRLPMDGKPLTVMPNSGYPKQENNRLVFDSSPDYFAQTTVGLVTRRTRLIGGCCGT
TPQHIHALRQALVGVEPPRTLAQTPVRPSIRPRVPAHPRLVDRLTQNKLTIAVELNPPRT
SQMEPLIAAARQLQLAGVDTITVTDSPLARVKMDSVCCASRLARETGLPILPHICCRDRN
ANALRSSLLAAHSEGIRQILAITGDAIPESYKGFVKPVFNLGSLGLIRLIQQMNQDEFAD
DPMLIAAALDPGVAKPEVELSRAMKKMEAGATLFLTQPVYDTRGLSLIRRVRRAGGKVLI
GLLPPVSYRNAQFLSQEVPGIRIPAKLLRRFCPDMTREAAVEAGLEATAEIARVMQPDAD
GFYLITPFNRADIMVQLHERLL
>A0A2H5YIX2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR24|TrEMBL
MDDPLISTGPEAALATGPLTLREKLAVGQFVVSVEIDPPVGLDARRAIRAAALMKEAGAD
AVNVGDSPTARVRMSPWALCLLIQREVGIETVMHYTTRDRNAMAIHSDMVGCHALGVRNV
LCLRGDPPELGGYKDVIGVWDVSAVGLVRILKLLNDGLDWTGRPIGRQASFFIGAACNPN
ADPLGPEIRLMRRKVEAGAHFFVSQNVFDPDRLERFLEQAAPFKRPIIVGVLPLHSYEHA
QRLHREVPGMYIPEDVRERLRRAGPDAPQEGKAMAREVMELCRGRAAGVYLVPTHGNYDL
VAELVAEGKG
>A0A093V657|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Talaromyces marneffei PM1|TrEMBL
MHVGQKLQEQAATGRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRS
ELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALEAAYNAGCTNILALRGDPPREQEK
WEAAEGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSTF
IVTQMFYDVDNFLNWVEKCRAKGINAAIVPGIMPISTYDAFMRRSNWTKIRIPPDWLEKL
EPVKADDAKVREVGTKLVAEMCRKLLASGHIHHLHFYTMNLAQATRLILEELRLLPSEEA
PLQKPLPWRRSLGLRRRSEDVRPIFWRNRNASYIARTADWDEYPNGRWTDARSPAFGELN
AYGVRLKGTNEQNIKLWGAPKSIKDLSDIFLRYLNGKLERLPWSDSSVTLETSDIQNELL
DLNKRGFLTINSQPAVNGVKSTDPVHGWGPRNGFVYQKAYLELLVPPEHVEELLRRIEKN
PDLTYYCINKTGELRARSDEGPNAVTWGIFASKEIIQPTIVESVSFMAWKDEAYQLGDDW
AKCHPADSPSRKLLQRVMDEWYILNIVNNDFHKNDDIFRLFDGLVIKDFETEVPGTAPEV
ADGTSTN
>A0A663BKB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella quasipneumoniae subsp. similipneumoniae|TrEMBL
MSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTYGANSGERDRTHSIIKGIKERTGLE
AAPHLTCIDATRDELRTIAQDYWNNGIRHIVALRGDLPPGSGKPEMYAADLVSLLKEVGD
FDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRAITQFFFDVESYLRFRDRCVSAGID
VEIIPGILPVSNFKQAKKFADMTNVRIPVWMSKMFEGLDNDAETRQLVGANIAMDMVKIL
SREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A1Q4Z854|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB03578|TrEMBL
MSGLRELLASGQRSFSFEFFPPKTDAGERVLWNAIRRIEAMAPSFVSVTYGAGGSSRDRT
VEVTKRMVAETTLLPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGNPNATWT
AHPQGLRHADELVSLVRASGDFSVGVAAFPEMHPRSPDWDTDIRHFVAKCRAGADYAITQ
MFFHVEDYLRLRDRVAAAGCDTPIIPEIMPATDARQIGRFAELSGAAFPEELAGRLEAAK
DNPADGHRIGVEYATAMADRLLAEGAPGLHYITLNRSTATLEIHQNIIESRSAHALAHG
>A0A239HBM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Antarctobacter heliothermus|TrEMBL
MQRPEISFEFFPPKNIEATFRLWDAVQVLSPLAPRFVSVTYGAGGTTRDLTRDVVATLHK
HSGLRTAAHLTCVNATRAETLAIAEGFAEAGVTDIVSLRGDPPKGSNGFEAHPDGFANSI
ELIEALAETGKFTQRVGAYPDRHPEAASQQASIEWLKRKLDAGATEALTQFFFEADTFFR
FRDDCAKAGIDTTKLVPGILPIENWNGARRFAESCGTHIPAWVSDAFDKAQRDGREDLLA
TAICSELCTNLIEGGVDKLHFYTLNRPELTRDVCFALGVTPDVSLEQVA
>A0A136N899|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium OLB11|TrEMBL
MNLFYHNYLIICFINASQSLISNISKYLFSQILNVCLNYICILMKVTEHIKKGNGKTLFS
FEILPPIKGKSIDSIFKILDPLMEFKPSFINVTYHRSEQIYRKKSDGSFERVEIRKRPGT
VGICAALMNHYKVDAVPHLICGGFSNDETENALIDLNFLGINNVLALRGDPPKNEKFYTP
HHSGHHYAIDLVKQIKNLNRGIYLESEISEGVKTDFCIGVAGYPEKHYESPNPDMDIMYL
KNKIDAGASYITTQMFFDNKKYHQYVKCCHDAQIEVPIIPGLKPISSKQQLSTIPSVFHV
DIPSDLAIEMMKSKNEKDTEQIGEEWLLMQVKDLIKSGVPVIHFYTLGKPNMVYNVMKKV
L
>A0A2N3AA17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-12|TrEMBL
MKVIDHINKAKKTLFSFELLPPLKGKGIQSIYDGIDPLVEFNPSFINVTYHREEFIYKKR
EKGYLEKIAIKKRPGTVGICAAIVNKYKVDAVPHIICGGFTKEETENALIDLDFLGIDNV
LALRGDPIKTEPAFIPEKEGHEHAVDLVKQIVSLNKGIYMDEDLQYAIPTNFSIGVAGYP
EKHFESPNMKSDINFLKQKIDAGADYIITQLFYDNNKFKKFVDLCRKNDIHVPIIPGIKP
LSNKSQLTTLSKFFHIDLPDDLVDAVEKCKNDDAVKQVGIEWAIQQSKELIDFKVPCIHY
YTMGKSVAVKEIAKAIY
>A0A4R5FDM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea mesophila|TrEMBL
MALGRPSFFPERVPTVRDLLADGGRSFSFEFFPPKTDEGERLLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERIARDTTLTPVAHFTAVDHSVRELRHLVGRFADAGVRNILAVR
GDPPGDPTAEWVPHPEGVLYAEDLVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTDYFVR
KCRAGADYAITQMFFEADDYLRLRDRVAAKGCDTPIIPCIMPVTQMSTIARSEQLSGAPF
PPRLAARFEEVKDDPAAVRRLGIEHGAELCQRLLDEGAPGIHFITFNRSSATREVFQRLS
GMRLSA
>K9RD42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rivularia sp. PCC 7116|TrEMBL
MLGTLNPTQLTTFRASAQAGEFLITAEVAPPKGGNPQHMVEMAATLKGRVHAVNITDGSR
AVLRMSSFAASVILQQQGIEPICQMACRDRNRIGLQSDLMGAHALGIRNILALTGDPVKA
GDHPDAKSVFDLESVRLLQLIEKLNNGFDSNDKALTDGATDLFVGAAVDPQCRSWSGLQK
RFERKLAAGAQFFQSQMITDFELLEKFMTQIAAGCNKPILAGIFLFKSAKNARFINKCVP
GVTIPEHIIDRLEQAKNPLEEGMKIAAEQVQIAQELCQGVHMMAVKREDLIVPILDMAGV
KAVRKF
>A0A7W1TIJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herpetosiphonaceae bacterium|TrEMBL
MAHPFVERLARGPLLCDGAMGTQLYASGIAFDRCFEVINLLEARRVADIHAAYINAGADI
IETNSYGANRFKLEQFALGDKVREINHRAMKIAREVREIAGTSTLIAGAVGPLGVVLEPY
GPVTPEEAQAAFAEQIEVLLEQGADLLMLETFSDLQEISLAVAAARAVSDLPIVAQMSFA
EDGRTTFGHTPEEVVTKLMALGVEVVGVNCSVGPQRVFKVLEAMHLAQPQARLSGQPNAG
WPTEQNNRIFYPSTPPYMARYARRMIEELGVSLVGGCCGTTPEHIRAMREALVDLAPDAP
AEHVHHIVPANPKPQGAAQQVAEPTKLARKLAAREFIVCVEIDPPKGHNPRKCIEGAMML
REHGVEFINVADSPMARVRMGPLAMCALLQQQTGLETIIHFTTRDRSLMGLQSDLLGAHA
LNVRNILTLKGDPPALGNYPGTSGVFDVDTLGLVKVVLGMNQGHDTSGHDIGTPTNFLVG
VPLNHNAADLDAEIAKFRLRVAAGANFAMTQIAYDAESFKAFLARLGPCPIPIILGILPL
QSHRQAEFLQNEVPGISPTFEAVHRMKLAGPEGRKEGVRMARELLREVRPLVDGVYVMPS
FQRWEVAAEVVDVL
>A0A3R6U3I2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. OM04-10AA|TrEMBL
MNIKEYIKEQRLITDGAMGTYYEEKYSEDTVIAEKENLKNPEQIKEIHLEYLRAGARLIR
TNTFAANTMFLADMQEVKETVRAGYEIAKEAVTAFQAENGKEIPVFIGADLGPIYDLDHQ
DYDNVLQEYKEICDTFLSCGADCFVFETQSDFTYIEPVTAYIKEKSDAFILVQFAFDKSG
YTRSGLSMQRVAVEASEMENVDAYGFNCELDSTHMYQFMKNLKFSSDKFVSALPNAGYPY
TLRGKTIYSNNASYYAEKMKDIAALGTDILGGCCGTTPEYIALLSGELQDVPKAAKKIEN
VVTQEVTRTPSIFEEKLSRGEKAYIVELDPPFSEDASKVMKGAEDLRKCNVDLITLSDSP
MARARMDAGQLAVKIQQKTGVAVMPHISCRDRNVIALRAGLLGMHMNDVRHFLIVTGDPV
SRADRERVTSVFDFNSIKLMQYVKEMNLEVFAQEPVYYGGALNYHGANPDAIIERMKRKA
EAGCGYFLTQPVYTEEDVERLTYIKEHIDTKIMCGIMPLVSYKNAMFVKNEMPGIHVSDE
IVNRYREDMTREEAEEVAIELSVEIAAKLYDIADGFYFMTPFNRTGLIARIIEAIRQEEE
RR
>A0A846UPE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobacter sp. SG703|TrEMBL
MTPISLEFFPPKTPEGVTKLAAVRQQLYALKPSFCSVTYGAGGSTQDGTLAAVQAILAEG
VEAASHFTCVGADRASVLAKLEQFKAAGIRRLVALRGDLPSGYGGFGEFRYASELIAFIR
EATGRQFHIEVAAYPEMHPQAKSPQADLQAYVEKVKAGADSAITQFFFNADAYERFVNDT
RKLGADIPVVPGIMPITNASGIIRFADSSGAEIPRWIRLRLQSFGDDTASIKAFGLDVVS
ELCERLLRVGAPGLHLYTMNAATAPLEICRRLKLD
>A0A258V6B7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. 28-62-57|TrEMBL
MNASYDQLREARTALDTPLFAGLPGDINVSFEFFPPKTDALMAQLWDVVETLAPFAPHFV
SVTYGAGGSTRDRTHGTVARIIKDAKLPAAAHLTCVDATKAEIREVAESYWEAGVRHIVA
LRGDMGAPGVPFTPHPDGYANAAELVAGLKTIAPFEISVAAYPESHPDSPNSQADIDNLK
RKLDAGATRAISQFFFEPETFFRYRDKLAAASIDAPVLPGILPVSNVAQTRKFAAACGAA
IPAWMDGLFEGLDTHPASRQLVAATIAAEFCRRLYAGGVRDFHFYTLNRAELSYAICHLL
GLRPTRPALEKAA
>A0A396MXV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF02-29|TrEMBL
MKIKDILAKGQPTLSFEVFPPKEESNFASVEKAALEIAKLNPSFMSVTYGAGGGTSQYTV
QIASDIQSTCQVPALSHLTCVSSTREKVHSVLREIQAHGIENVLALRGDIPKDGKVEKDY
QYASQLIREIRETCPDLCIGAACYPEGHVESVNKTVDIGHLKEKVEAGCDFVTTQMFFDN
NILYNYLYRIREKGITVPVVAGIMPVTNISQIKRICSMSGTYLPARFKAIVDRFGDNPAA
MKQAGIAYATEQIIDLIANHVNGIHVYSMNKPDVAAQIKNNLSEIL
>A0A078S0B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides uniformis str. 3978 T3 ii|TrEMBL
MRVIDLINSNEKTAFSFEILPPLKGTGIEKLYQTIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITMVPHILCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESSFIPVGNGYHHAVELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNMDTDIYWLKKKMEMGAEYAVTQLFYDNRKYFDFVERARQAGVTIPIIPGIKP
FKKLSQLSMIPKTFKVDLPEELTQEVLKCNTDAEAQQVGIEWCVQQCKELIAHGVPSLHF
YSVGATDSIKEVAKQIY
>A0A1B1YFZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoclostridium stercorarium subsp. thermolacticum DSM 2910|TrEMBL
MKITEFFERKKQTVSFEIFPPKLDTPIETILNKLGDFAQLKPDFISVTYGAGGSKKGRTV
EIASKIKNEYGIESLAHFTCVGHSIEEIDDMINKLKNEKIDNILALRGDPPKDMPDFDFS
KNVFSYASELIRHIRKRANFCIGAACYPEGHVDSPRIRQDIYYLKQKVNEGVDFLITQLF
FDNRIFYDFMDKLLAAGITCPVLPGIMPIFRADQIKRIASMCGASMPAKLVLLLDKYGNT
PDMQKAGIEYATNQLKDLLDNGVHGIHINTMNNVEATRTILQNLGLFPG
>A0A258V2Q4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Novosphingobium sp. 28-62-57|TrEMBL
MATPLIHPNWDKAPAGITDGFSLEMTAKDEASLRDAAPLIPAETPVAITFLPGEDVAARV
AATVAVRELGFEPMPHFSARRITSEDDFEGYLRAVVEKAGVERCFIVAGDPPEPVGPYFD
TSALIATGAFERSGIKAIGIGGHPEGHPNMTEAECWAVLEKKVAEITARGMAPLIVTQFG
FDPDAFLSWLKELRARGIDAPVRIGVPGPAGIKRLLAFAARCGVGASTSVLKKYGISVTN
LLGTAGPDKLVDAFAKGLGPEHGKVRLHFYPFGGLTKTLEWLHGYNKKHGINQ
>A0A4Y9ND99|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastococcus sp. AZ43|TrEMBL
MTGTVRELLASERPTWSFEFFPPKTPEAEPQLWQALRELERLQPSFVSVTYGAGGSTREG
TVSVTERIATETTMTPMAHLTAVDHSVAELRHVVSRLAAAGVKNLLALRGDPPGADPQAE
WTAHPEGLNYAAELVELIKSMGDFSVGVAAFPERHPRSPDFDSDVTRFVEKCRAGADFAI
TQMFFRAEDYLRLRDRVAARGCDVPIIAGVMPVTNARQITRIVQLSGQAFPADLADRFAE
LDGDRPEDKAAVRAYGVEVATELCRTLLAEGVPGIHFITMNRSTATREVYANLARLPAIS
>C4L7B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tolumonas auensis (strain DSM 9187 / TA4)|TrEMBL
MSFDSARQVEALNQNLAELSGDINVSFEFFPPATESMEQTLWNSIERLSKLKPSFVSVTY
GANSGTRDRTHSIIKDIKERTGLVAAPHLTCVDATRDELRAIAKDYWDNGIRNIVALRGD
LPPGAGKPEMYANDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLHLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAAIGIEAEIVPGILPVSNYKNLLKFAGFTNVKIPQWLHQRFE
GIADDDQMTRNMVGASIAIDMARVLSREGVKDFHFYTLNRSELTYAICHTLGVRPKA
>A0A6B2NQR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria sp. PrR005|TrEMBL
MTAPQISFEFFPPKNLEASFRLWDTVQVLAPLAPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLNVAAHLTCVQASREETLAIADSFALAGVTDIVALRGDPPQGAGHFTPHPGGFANSV
ELIQALAETGKFAIRVGAYPDIHPEAASAQADIDWLKAKLDAGADEALTQFFFEAETFFR
FRDACAKAGIDKQITPGILPIENWKGARNFARRCGTYIPAWVEDAFDKATRDGREDLLAT
AICTELCSELIDGGVDKLHFYTLNRPELTRDVCHALGVTPKVALQNVA
>A0A0D0WPV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora haikouensis|TrEMBL
MALGLPSVLPNPQPAIGELIRDRQPTFSFEFFPPKTAQGERLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRNVIGRLAGVGVRNVLAVR
GDPPGDPGGEWVRHPEGVLYAEDLVRLVRDSGDFSVGVAAFPYKHPRSPDVASDTAHFVR
KCRAGAEFAITQMFFDADDYLRLRDRVAAAGCDTPILAGVMPVTQLSTIERSVQLSGAPF
PPALAARFAEVADDPEAVRRLGIEQAAEMCRRLLDEGVPGIHFITLNRSTATREVWQQLQ
VGARV
>A0A6J4P0T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ramlibacter sp|TrEMBL
DIPDQSRVLPAQDRRGRRQASRRAAAALFASPRVLLGDVRRRRVHPGRHPVRGQGDHGGR
LRRGAAPVVHRPEPRKHPRKAGGLRGRRREADRGLARRPAEWLWAGRRVPLRQRPGRLHP
QRDRPPVPAGSGRLPRGASAGEIGRCGHRRFPGQGRGGCRCRHHAVLLQCRRLSALPGRT
DSTRRGGSGGARHHADHQLDPALALFRCVRRRDPALDPVAPAGVRRRRRVDQGVRPGRGG
RPVRKAAHRRGAGAALLHDEPVGRDAGDLPAPGAL
>A0A435XA02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7D.F.Ca.US.004.03.1.1|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTART
>A0A416NY93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium AF22-6AC|TrEMBL
MGNTKHTKEQIRERIQQKKLLFDGAFGTYYGGKYDTKQLPELANLEAPERVKEIHTEYLE
AGAQILRTNTFAANSFCMDMSKEQIEETLRSGVRLAREAVVAWRERTGETKEVYIAGDIG
QIPCDALAQKDTLCREYEEICRIFLEEGVDFFVFETFSEMEEILPAIKMIGEQAFITVQF
SVNQFGYSNAGLSARKLLQRAGAIKEIDAVGFNCGVGPSHMYRILQTLYKPADKFLTALP
NAGYPQMVTGRMIFTGDNREYFVDRMQQMIALGVDMAGGCCGTTPEYISDLAGKLDFTQY
PQTQEKAEPEKKQAGTEDHSFYHIKEAEGGKKLIAVELAPPAGIDDEKLMDAAHLLQRSG
VDVLTFPDSPSGRTRADSILMAEKVARETGMCVMPHICCRDKNAIAMRSQLLGAYINGIH
NFLVITGDPIPSMVRTTVKSVFNFDSVGLMQILADMNEEQFAQAPVSYGGAINQGRRNLE
VEIGRVKKKMAAGATFFLTQPISTRESADRVRRIKEETGARILCGIMPFVSLKNATFMKN
EMAGIDVTDEVLARYRADMTREEGEQAGVQLAKEVIAMTEDFADGYYFSFPFNRVTMLEK
ILD
>A0A073KUX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus gaemokensis|TrEMBL
MKLLDLLATDIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRIYGLENQVVQINRAAVKLAKAAAKDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALIEEKVDGLLLETFYDEFELLHAVKVLRKQTDIPIIAQLALHEAGTTQNGN
DVNGILAQLLDYGANVVGLNCQLGPLHMTEAFKMISIPENGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPAHIEGMKRGIANVTPVTEKKIVQRPQVIH
TQTKRSRTHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPDEVRERMDGHETQEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITENLVKYVR
EKQDVKEGIN
>A0A6I7X229|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylococcaceae bacterium HT3|TrEMBL
MTIKNKADLFSFEFYPPKTEQGDLNLEQVHRDLAKLNPDFFSVTFGAGGSTRDKTYDTVV
KIQKNGVSAAPHLSCVASTKENIREILANYREHGVSKIVALRGDLPSGMMSAGEFRFANE
LVDFIRVETGDHFQIHVAGYPEVHPQAGNATEDFNNFKRKVDAGADAVITQYFYNAEAYF
YFLDKCEKSGINIPIVPGIMPITNYAQLFRFSDMCGADIPRWMRKTLECFGDDKASIMAF
GEDVVSKLCQELLDNGAPGLHFYTMNQSKPTLVVWDNLSFA
>A0A642VA64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichomonascus ciferrii|TrEMBL
MSKFGPAFVTVTWGAGGSTATKSLDLAETCQQDLGLCTCLHLTCTNMDQKILDDALEQAR
KLGIKNILALRGDPPRADEYDVSMNGSKDFNYAIDLIKYIKSKYGDEFCIGVAAYPEGHV
DGVDDSDQNPDHDIPFLVEKVQAGADFIITQLFYDADTFIRFEKKLYEHPSGVFKDIPLI
PGLMPINTYQSFLRAAKLSHASIPDHIMKGLSDIPTGDDEQVKQYGVKLLCDIIARIKSE
TNGRVRGFHFYTLNLERAIALILEKSGLLMPHHHHHEDSAIASDDEDETLRRHPQARKHR
KSSASSTLNKVIVDNNLNDPEDQISDRLVGHQSVESLRDTALAISTGEGDLGREALWDDF
PNGRFGNAKSPAYGEIDGYGPTLHVEKNRALKIWGYPVDAKDISTLFVKHITNELEALPW
SEEKLSPETSLIQEELIQMNQRGMWTLASQPSGNCVKSTDKIFGWGPPGGHIFQKAFVEF
FISHEDWVKLKQRLEKEDVANISYYEGTSATSKIQSNLPSGSSNAVTWAVFPNREVVQST
IVEEESFNAWRDEAFNIWKEWQRLYHPSSPTFKLLDNIHKTYHLVSVTHHDFFNSHALWD
FLLE
>A0A2M6V713|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnohabitans sp. G3-2|TrEMBL
MSGLKLPISLEFFPPKTPEGAEKLRVVRDKLYTLKPEFCSVTYGAGGSTQEGTFSTVSAI
LAEGVAAASHFSCIGATKASVREELATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLV
AFIRTETGDDFHIEVAAYPEIHPQAKSPESDLQAFATKVKAGANSAITQYFYNSDAYFRF
VDDAYKLGVDVPVVPGIMPITSSSQLLRFSDACGAEIPRWIRLRLQGYGDDIASIKAFGL
DVVSDLCEQLVNGGVPAIHFYTMNQSAATLDIVERLK
>A0A239PMZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus seriniphilus|TrEMBL
MSRATPKISFEFFPPKTLDASFRLWDTVRALAPLSPDFVSVTYGAGGTTRQLTHEAVTTI
NRHYGLNVAAHLTCVEATREETLKIVQDYADAGIREIVALRGDAPKGQDHFIPHPEGFAH
SVELIEAIAARGDMTIRVGAYPEPHPDSNGTDADVTWLKRKIDAGASSAITQFFFEAETF
FRFRDRCAAAGIDAPIIPGILPIQGWAGARRFAQSCGTSIPQWAEEAFEAAIRDGGDREK
LLATAICAELCDKLLDGGVDRLHFYTLNRPEMTRDVCAALGLHPARELEAVA
>A0A1F1EFM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. HMSC077D03|TrEMBL
MTPRLSASAPLDQINEWTARVRQRTALSFEVIPPRNDADASKISELLAVLQSYHPDYIAV
TSSQRSGWLRGTAAFIEQIARTTSMRPLAHLACTAGSPGELSEWVDVLVDSGVRGFLALR
GDLPEDGMPAGYLQHADELIRLIRRREAAQAARFAAGNLAVGVACYPNGHAESANADEDI
DVLLTKQRLGANFAITQLFFDPEDYARFYQRARLAGVRIPLIPGIMPMTSVARLERMAGL
SGLDVPPKVRAALAAAKTPEDEQEIGMELTAELARGVLRAGAEGLHIYTHNNPAITQDLL
SRIGVNR
>A0A1V8RW44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudaminobacter manganicus|TrEMBL
MNQFRFSRQPDIGERIRVSFEFFPPKTDEMETRLWDTVTRLEPLRPNFVSVTYGAGGTTR
ERTGRTIKRILTETGIPAAAHLTCVGATREEVDAVIREYDAMGIRRFVALRGDPANGVGE
AYQPYPGGYQNGAELVGGLKSIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHNFRQVANFASRAGTHVPAWLAERFE
GLAQDPQTHALVASAVATEQVMDLVERGVSDFHFYTMNRADLVVAICHMIGIRSPQGIVG
SAAA
>A0A4R8QZB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Colletotrichum spinosum|TrEMBL
MHIKSMLDETRRTGEPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVLQAQSIYGLETCMHLTCTDMGLEKVNDALRKAYKAGCTNILALRGDPPREHEK
WEATDDGFQYARDLVKHIRATYHDHFDIGVAGYPEGCDDNKDEDQLLDHLKEKVDMGASF
IVTQMFYDGDNFVRWVGKVRERGITVPIIPGIMPIATYASFLRRAKHMNCKVPDEWMAAL
EPVKNDDVAVREIGKGLVADMCRKILAAGIHHLHFYTMNLAQATRMVLEELNWMPSNERP
LKHALPWKQSLGLGRREEDVRPIFWKGRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEQNRKKWGEPRSIKDIANIFVRYLETEIDTLPWSEAPLTSEADPIREELIG
LNKRGLLTINSQPAVDGVKSSHPVHGWGPPNGYVYQKAYLELLVHPDMYPEIISRIEKNP
DMTYYATTKNGPLKYNAAHDSPNAVTWGVFPGKEIVQPTIVEGISFMAWKDEAFRLGTDW
AHCFEAGTPSRVLLDRIMNEWYLVNIVNNDFHQKTALFDLLDGLSIKEYNDIPSEPQVQT
KGQANGVSKEQASELSNGNVAPIPA
>A0A3S2Y097|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucilaginibacter limnophilus|TrEMBL
MKITDHIKNANGKTLFSFELIPPLKGQSIQGIYNAIDPLMEFKPPFIDVTSLREDYIYKQ
HDNGLLEKLSYRKRPGTIAICAAIMNKYGVDTVPHLLCGGFTKDETENALIDLNFLGIEN
VLVLRGDARRGDATFVPTTGGHCYATDLLQQVVNMNNGKYLHEDYDGIEKTNFCIGVAGY
PEKHFEAPNLKSDFNYLKQKVDMGAEFIVTQMFFDNQKYFDFVRKCRENDINVPIIPGLK
PITASKQLVSLSKTFFIDMPEDLCDAVNACKTEKDVKEIGIEWMINQCKELVNFGVPVLH
FYTMSNPGPTRRIAEAIF
>A0A3S9B358|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Georhizobium profundi|TrEMBL
MNAVIGLKQHQSTHIAASIEVAPKQAIESDDLPGLFPHGTRVYITDIGTATDEMVAAAIR
IRSLGYEPVPHLACRRLTTRVALTDRVERLSREAGVRDALIIGGGLERQAGEFSSTMEVL
ETGLFDRFGFTDLGVAGHPEGSPEFNEEVALHALRLKKSFAERTGARMRIVTQFGFDAER
FIDWSEGLRMEGIDLPVHLGVAGPAKITTLIKYAALCGIGNSVTFLKKNALALTALATSH
SPETVVGPIERHVAATPHSAIKQIHVFPFGGLKKSAEWLEQRGSWDIKTSLYPSMPLIAE
R
>H1WEF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnospira indica PCC 8005|TrEMBL
MNRFRTACLNPKEFVITAEVAPPKGGDPTHMIEMARGLKNRVHGVNITDGSRAVLGMSSL
ASCVILQHHGIEPILQVACRDRNRIGLQADLLGAHALGIRNILALTGDPVKAGDHVNAKP
VFDFESVRLLQAINKLNNGMDWNDKKLPHGRTDLFPGAAVDPQSPSFSGLQSRFYRKLKA
GACFFQSQLITDFERLYKFMNQVASDTDKPILAGIFLLKSAKNALFINKYVPGVNIPDHI
IHRLEKSSHPLEEGIKIAAEQVQIARQICRGVHLMAVKREDLIPKILDAANIPPLP
>A0A8G0A5I0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gilliamella sp. ESL0405|TrEMBL
MKTNLLFNKKTVFSFEVFPPKKTSPLETIYSTLRELGYFKPDFISVTYGAGGSLNGQTTI
DIAHSVKHTYGIESVAHLPGINFDKAEMQKILHDLKCAGIDNVLALRGDISPTVTPKDDF
RYASELVSFIKENGDFNVIGACYPEGHLEASTLKQDLIHLKEKVSAGTDQLISQLFFDND
YFYTFLDKARDMGINVPIEAGIMPVTNKNQIERMVSMCGVNLPKKFKQMMEKYEHHPDAF
RDAGIAYAIDQIVDLVSQNVDGIHLYTMNNSYIARRISEAVSTLLAVPKSE
>A0A168LEF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Absidia glauca|TrEMBL
MKVIDKIHAAEKEGRLFWSFEYFPPKTPQGVQNLYDRMERMQRMGPEFIDVTWGAGGTSA
DLTTEIVSTAQSVYGLETMMHLTCTNMGIEKIDTALKAAKECGCQNILALRGDPPKGQSN
WESCDNGFEHAVDLVRYIRQQYGDYFCIGVAGHPEGHSDCPSKEQDLLHLKAKVDAGADL
IVTQLFFDVDAFLDFVNQARAIGIDCPILPGVFPIQNYTGLKRVISFSNNHVPQKIWDDL
EPLKEDDAAVKEYGINLTIDFIHRFQQAGIRGFHIYTFNLERSTRLILERLELVAPLEAV
KPLPWNPALTQKRAKENVRPIFWKNRTKSYIQRTEFWDEFPNGRWGDSRSPAFGELDGWG
VSLKYSTEQCQDMWGHPETVDDVAVVFAKYCKGKIAGIPWSAQPLEAETETIRQRLAGIN
LLGYLSINSQPAVNGVKSSHPTYGWGPKNGYVYQKAYLEFFVSPHHLDDLINKIGKDPNV
TYYAVNKQGDLRANTQSDHPNAVTWGVFPGKEVVQPTIVESTAFMAWKDEAFELWNEWAR
IYDRKTKSADLILDIANNWYLINIVHNDFQDEGGIWRLFDLEIDGEISRKIRQNDGDC
>A0A844YUR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pelagerythrobacter marinus|TrEMBL
MSPTFDQMQEARTALDAPLFSGLAGDIDVSFEFFPPKTEKMAQTLWDSVQTLAPLGPRFV
SVTYGAGGTTRERTHEQVVRISREAHIPAAAHLTCVEATREEIDDIARHYWDSGIRHVVA
LRGDPPDGQSHYAPHPGGYANAAELTAGLKAVAPFEISVAAYPEVHPDARDAAADLDNLK
RKFDAGATRAITQFFFEPECFFRFRDRAVAAGIDGEIVPGVMPVMSFASVQRMATLCGTA
IPGWMAGLFEGLDERPAARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRPGGGGR
>A0A3D8Y4W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dyadobacter luteus|TrEMBL
MTKVTEFISQANGKTLFSIEIIPPVKGQNINELFDSIAPLMEFKPPFVDVTYHREELIDR
VGPNGLIERIPVRKRPGTVGICARLMERFHVDAVPHVICGGFTKEETEDVLFDLHYLGID
NVLVLRGDPEKSAGVFHAKNGGHTYASELVTQVADMNKGILLNAETETTPTDFCIGVAGY
PEKHIDAVSLDTDFEYLRKKVELGADYIVTQMFFDNQKFFRFVDRCRAEGITVPIIPGLK
PLATKKQLTVLADIFHLEFPEDLVKAATAASEKDVRQVGIEWGVQQCKELLAYGVPVLHF
YTMGKSDNVAQIARQVF
>I5C9A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitritalea halalkaliphila LW7|TrEMBL
MKITTYIQEAKKPLFSFEILPPLKGQSLKDLLDGIEPLMEFQPPFVDITYHREEFIYKER
PGGLLQKVSTRKRPGTVGICAALMSRYQVDAVPHLLCGGFTREETENALIDLSFIGVQNV
LALRGDAPKATGVFVPEAEGHVYTKDLVKQITAMNRGQYLHEETETGFQTDFCVGVSGYP
EKHFEAPSLNWDLKYLKEKVDAGAEYIVTQMFFDNARFFDFQRRVRELGITVPIIPGLKP
ITTLGQIQALPRTFFLDFPDALMLELEKCRSNAEVREVGIEWAIAQSKELVAAGVPVLHY
YTMSKAEATRRIAAEVF
>A0A356U732|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophomonas sp|TrEMBL
MKILDLYGREKPILSLEIFPPRVDYPLETIFETLDHLQTLNPGYISVTYGAGGSNRARTV
EIAARIKKDYGIESLAHLTCVRHTRSEVGQILDQLAHEEIRNILALRGDLPEDAPDFDLN
KQDYRFAYELINDVRQKADFGVAAAAYPAGHPECLRLKDDLRNLKHKVDCGVDLLITQLF
FDNRIYYDFIDKARAVNINCPVIPGIMPVLNARSIRRTIYLCGASIPAPLLQLVDKYEHD
ATSMEKAGIEYASMQVDDLLTSGVQGIHLYTMNKHRQIIEIVKNVGLVK
>A0A2S5XCI1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rathayibacter sp. AY1C5|TrEMBL
MTRARFEIIPADDIGERAARAFPDPSAVTLTVTSLPKHGTGRTVDCAVALAGRGFRVVPH
LAARNVEGRAALERVLERMGEAGIDEAFVISGDASSAAGTYSTSLELIRDAREISPGLAM
DIAGYPEGHPHLSDESIERHLRERAPFIRSIVTQMCFDVDAVVRYADRLRETGITADLWA
GVPGPVARSRLLTLGARIGVGSSLGFLKRSTSVAGGLLRGRRFDPSAFVARLEAAAGDRL
AGLHVYTFNELDSLAAFG
>A0A2P5IIN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. PSNIH6|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWHSIDRLSSLKPKFVSVTY
GANSGERDRTHTIIKGIKDRTGLEAAPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPANGGKPDMYACDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGASRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLTRFATMTNVRVPGWMNAMFD
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPVLAA
>A0A0A1PLM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium YEK0313|TrEMBL
MSTSYKPSRYVSRSRLKVSFEFFPPKSEEMEATLWESIERLAPLAPTFVSVTYGAGGSTR
ERTHATVQRIIAETQLKPAAHLTCVAATRGEVDDVIRGYWAAGVRHIVALRGDPVGGIGT
PYASHPGGYDGSPELVAGIRAIGDFEVSVSAYPEKHPESGSIDTDIEMLKRKVDAGATRA
ITQFFFDNEVYLRYLDRARAAGITIPIVPGIVPVQNFKQTAGFAARAGASIPDWLARRFE
GLEGDPATRKLIAAAVAAEQVFDLVDRGVTEFHFYTMNRADLVYAVCHLLGLRPEGETAR
AAA
>A0A1Q8T7Z1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salinicola sp. MH3R3-1|TrEMBL
MSTQPSLGISFEFFPPNTDAGREKLGGVRDALAARSPRFFSVTYGAGGSTQARTFDTVNK
VRRSGVNTAPHLSCIGSEKSALRELLQTYREEGIDSLVALRGDLPSGMGGAGELRYANEL
VEFIRSETGDHFEIAVAAYPEAHPQAPSFERDLENFARKAKAGADLAITQYFFTADAYFH
FVDRVRGMGIETPIVPGIMPITNYTKLARFSDACGADIPRWIRKQLESYGDDSESIQDFG
TEVVSNLCHRLLDGGAPGLHFYTLNQSAPTLRVLDNLS
>A0A031GC06|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. RIT288|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A3R9UE83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. WAC06614|TrEMBL
MPAALAATIERPRTSPTPSVRELLAEGRKSFSFEFFPPKTEAGERTLWKAIRRIEPLAPS
FVSVTYGAGGSSRDRTVEVTKRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGIRDV
LALRGDPPGDPKGEWTPEPDGFRHAHELVSLIRQLGDFTVGVAAFPERHPRSPSWTEDVR
HFAAKCRAGADYAITQMFFHVEDYLRLRDRLAAVGCLTPIIPEIMPATDHRQIARFAELS
DARFPEQLAARLEAAQDDPADGHRIGVEYATCMAERLLAEGAPGLHYITLNKSTATLEIH
QNLDLGPHT
>A0A7W6DQP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sagittula marina|TrEMBL
MALFNFRTRDPQRGLSPSNGAVEAFLQGYSIEVMPRTAAKVENFRDLLPEGTRVYIAHIE
GTPIEEMVATAKRLNDEGYPVMPHFPARIIKDAATLENWIAMYQGEANVKQGLMLAGGVS
EPHGDFHSSMQLLETGLFDKAGFERLHVAGHPEGNRDIDLDGTDTAVMQAAHWKQSFSER
TDAKMAMATQFAFEAKPIIEWVNRLNAEGIHLPVHIGIAGPAKLQTLIKFAIACGVGPSL
KVLQKRAMDVSKLLLPYEPTDVLTELATYKAANPDFGIENVHFFPLGGIKTNAQWAIDNG
GDAGKPANR
>A0A5F1PC58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tabrizicola sediminis|TrEMBL
MATPRISFEFFPPQTLDASFRLWETVQALAPMQPEFVSVTYGAGGTTRKLTHEAVTAIGK
NYGLNVAAHLTCVDATRAETMEIAAAYADAGVTEIVALRGDAPKGAERFTAHPDGFASSV
ELIEALAATGKFKLRVGAYPEPHPDAADTLADVRWLKRKIDAGATSAITQFFFDADTFFR
FRDLCVKEGITAPIIPGILPITSWAGAKKFALRCGSDVPARLDEAFTTAARDGREELYAL
AHCTQLCDNLLQGGVEDLHFYTLNRPHLTREVVRALGIQPELVPELVLEKVA
>A0A7V1WSF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastocatellia bacterium|TrEMBL
MKSFRDLLEDDSVHVFDGAIGTRLYEKGIYINRNYDEINLAAPELVLEIHEEYVRAGAEI
IETNTYGATRHKLQLFGLENKLREINIAAAQIARKAAGDKVFVAGAIGPLGLRIEPYGPT
SFDEAKDMFKEQAEALLEGGVDLFVIETFSDLSEIQQAIKAIKEICDLPIVAQMTIQTDG
KTTFGADAKLIALRLEEYGADVVGLNCGVGPTHILNALEQMREITDKKLSAQPNAGLPRD
IQGRQFYMCSPEYMSKFAKRFIKAGASFIGGCCGTTPKHIKMICDVVRALSPRVQKFYIR
RQETVRVEELTPPDVQVVPAEERSNWARKIARGEFVTSVEVLPPKGIDAGKTLESIKLLV
DAGVDAVNIPDGPRAQTRMSALATAVLVQQTVGIEAVLHYCCRDRNLLGMMSDLLGAAAL
GVNNLLIITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNPIGKPTRFSIGV
GVNPGAVNIDEEIRRFEWKVEAGAEYAITQPVYDTKQLRDFLKRIEHCRIPIIAGIFPLV
SYRNAEFMHNEVPGVNVTPEILERMRKASAISKEAAREEGLRIARESLLEIRDLIQGVQV
SAPFGNVKYALQVFEVLDEFKDRQKQAQTL
>A0A8F9TAB4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. So3.2b|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEAKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKAEAGANSAITQYFFNADSYFY
FVERVQALGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCETLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>A0A848X2V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MSDLVAGMLDDGRVHVFDGAMGTLLYSRGVFVNVCYDELNLSRPELVEAIHQEYAAAGAE
ILETNTFGANPVKLSSYGLEGRTEELNEVAARLARKAAGGDIAVAGAIGPLGIRIEPWGP
TSLDEATDHFRRQIRGLLEGGVDALVLETFSDLSEIGCAVRAARAESDVPVIAQMTVGQD
GRSQYGTSASQIAQGLAESGADIIGLNCAVGPAVMLDAIEEMGDVTDVPLSAQPNAGLPR
TVRDRKIYLASPEYMAQYARRMIDVGVRFVGGCCGTTPDHTKKMRDAVAALQPKHTSVAV
PRASFEDPALTEPVPLDARSAWGRKLSRGEPVASVEIVPPHNWNALEVTEPARKLKVAGV
DVVAIVESPRSRSRMSALSAALIIEREVGIESLVHYTCRDKNMLSMISDLLGAAASGLRN
VLVVSGDPPTMGPYPDATAVFDIDSIGLTNVVQGLNRGVDPGGNSIGAPTEFVQGVALNQ
GAVDEERELSRFGYKVEAGADFVVTQPVFEPDALEAFLDRAGPVDIPIVAGIWPFVSLRD
AEFLANEMPGVDVPVRIVDRMRKAQKSGSEAATEEGVAIALEMIEAVRPVVQGFHLTAPH
RKVHVALRVLRESGLRATA
>A0A7Y2G8C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
VHRAYIDAGADFVETNTFGANRFKLEPHGLGDQVARINRTAAALAREEAGDATLVGGAIG
PLGVPIEPIGRIGFDEARECFRLQAQSLVEGGVDFFLLETFRRLEEIREAIRAVREVAPD
KAVVAMISITDDSESALGDSPERIARFLDEQEPDVIGLNCGVGPQPTLAAIEKIISVTDR
PTCVMPNAGMPRLVEGRYMYLSSPEYFAKYAQRFLRVGVRVLGGCCGTTPDHVRAIRRTV
RSARPAEYHERPRATTFVLERDREGPAPAKREEKSSLGAKIAAGQFVCSVEISPPKSADP
SKTLKRIQVLKDGGVDAVNIPDGPRASARMSSQALALLAARDTGMEAILHYCCRDRNLLS
MQSDLLGMGALGLKNVLIITGDPPKLGDYPDATAVFDVDSIGLMQVANRLNHGQDLVGNP
LDMPTSLHLGCGANPAAVNLDEEIRRFEYKVEAGAEYVMTQPVYDPAVLKRFVDRTEHCR
IPLLVGILPLRSVRNAEFLNNEVPGMDVPDSILRRLGEAASPDEARAVGIEIAREALLES
LPYAQGVYVMPPFNSARSALQVLEVLPETHRSRMAG
>A0A8H3T609|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus tubingensis|TrEMBL
MMLAAMGSAVRHGAFSGGSIGGRKSCSSPPPSFTPSSFFAFHSLSSVRHRVAVSAAETAL
IMEKITDKIAALPPDANYFSLEFFPPKTKMGFANLQARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEICQRQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRKQYGDYFCIGVAAYPEGHPADNFQDVQDPARDLPY
LIEKTQAGADFIMTQLTYDLEAYTKFETMLRNHESGVFKTIPIVPGLMPIHSYKILTRVT
KLSHVKIPPQVLSKLEEVKHDDDAVKRIGVDIITDLVYGIRDLVSPGLRGFHFYTLNLEK
TVSFILERCELIPPYTEIDDSDALVDGGNLSAMDSSSYIAPNGAPIRTLASRRSSVSSIP
HNRVIVDKVQISEPSSKDSITHEASALSAGLPAMPPDRSTTLQISEGLGALGREATWDDF
PNGRWGDARSPAFGEIDGYGPSLHVSAATARRIWGYPVTREDISTLFRRHVSGELHMVPW
SEGGAEEDSNGLNAETAVIQPELLTLIDKKGWWTLASQPALNGVRSDDPVFGWGPPGEGF
VFQKPFVEFFCPSKDYLNVLKPLLQKHGHEKLAWFATNVKGDFESSLPGPNPDDPDPIDI
NPANVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAYRIWDEWRRIYPKNSATERFLDET
KNDVWLVCVVGQEFGAGTEAGSEEEEDEKKWMWRELANSQ
>A0A3N4AYN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia pestis|TrEMBL
MERKLSFEMNSAKNEKEMENIFKLIEFTDTLDPIYYTVNTEIGSSVWSDTYRTVIELREK
TDVPLIPHITINNKKEREIMQIIEKYINVGICEFFVIRGDKHVYDQDNPINYGVELIELI
RRSHKHIGIKTSLYPDFHKETTEVKEEIDWNERKYQLGVNEFISQLTLNTNALDFLSHWV
DKERPFTPSIMPLGNFSFIEKFTSSNSIDYPLWIKKFANSKSNSNEDKENIGIEIIRFLC
REYLNQRERLHVFTLNKVDVMKKIFQ
>A0A7T1HUR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. CBW1004|TrEMBL
MGRIEGGGPLLREALERGEFALTAEVTPPRGGDPSRTLAAAAALRGLVHAINVTDGSRAV
MRMSSLAVCRLLLDAGIEPVWQVTGRDRNRIALQADLLGAQALGIRNVLCLTGDPVKAGD
QPEARPVHELESVRLLQLVQSFNQGIDPVKGELPDGGTSLFAGAAADPQTGSWSGLVSRV
KRKQQAGARFLQTQMVMDPEALRRFVEEVSGPLGLPVLAGVFLLKSAKNALFINRVVPGA
SIPQAIIDRLAGASDPAAEGIAIAAEQVAAYRDIAQGVHLMAVKAEERIPAILQLAGIQP
RPVPPLPAAVG
>A0A2T3HW16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium aquimaris|TrEMBL
MVNLDQTTQAESELRVRYNDITRGVYFIGTTPPKTSTPLEEVEGIADRLVNRIKDLAIDG
LIVYDIQDEVSRTQKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSETDAFDEWL
NEAWHEYQVRDIVLVGSPSAKNEVSLPLSAAYQTLAENNNNFFTGGIMIAERHAKKGNEH
ARLIEKYQQGCNFFISQAIYDTQATIDILTRYAIECKQDGIKPQRILLTFSPCGSAKTLE
FIEWLGVSVPEATSLRILNASNPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRK
EEIDGSILLYKLLRASMDSHLAKHEFRTLQRNKLTSV
>A0A6N9AQU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MNTSLLDHLQSSLLVADGAIGTMLYARGVPMEVCFDEINLSRPDLIRKIHEEYVDAGAGL
IETNTFGANALSLSKYNLEDQAESLNARGIEIARQAVGTRAYVAGAVGPARGLPHREYTE
DDHRRVYTEQIAALAGGGADAIILETFLRLDDLKAALAVCREVCGLPVICQLAVDQYGQS
DDGFEVVEAFDQLRAAGADVVGVNCRSGPKGLLDALAPVPLTEGLVLSAFPNAGSPVYVD
GRFIYEATPEYFATSALRLRDQGVRLIGGCCGTMPEHVQAMAQALEGREIVKRKKVLPVE
VRVPARPAGPGRPARPAPAPPAVEPSIVDLVKERVTVIVELDPPRDLDHGPIVRGAKALK
KAGADALTMADNSLAVTRISNMAVGQIVKEEAGIRPLLHITCRDRNLASLQSQVLGLHAL
GIDHVLAVTGDPVKFGDQPGASNVYDVSSFELIRLIKQMNEGVGFSGRALNGRTAFTVAA
AFDPNGPNLDRRIRRLERKVEAGADMIMTQPLFDHRQAKQLYEATRDAAIPILPGVMPLV
SDGNTEFLHNEVPGFVVPDEVRARMARVGRGRKARREGVAIARELIESVLTYFNGLYLIT
PFNRYPMTVELTEFALQAAARNTSG
>A0A3M1HE02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldilineae bacterium|TrEMBL
MTHPFLNRLEAGPLLLDGAMGTEIYARGLNFEQSLEETNLTQPQVVKAIHRDYLAAGADV
IETNTFGANRIRQEDFGLGEKAPAMARAGVRLAREAREEAGRPQVWVAASIGPLGKYIMP
YGSVGEKTAEEVYGETIQALVEAGADLLVFETFSDLAELLLAVRVARSLCDVPIVAHMTF
DEDGRTALGHTPEGVARMLAQAGVDAAGANCSVGPAGVLEVIRRMHRAEPHLPLSAMPNA
GFPTRVGGRLLYPSTPDYFASYVEQFRAAGASLLGGCCGTTAAHIRAMRAALDGGPKAVT
PVIPAVPEHYPLPARPQELAPTVLERALQERFVVTVELSPPRGYDPEPMLENVRALQQAG
VTAINVADSPRARMRMSPWAAAHLLQTRLGIETILHFPTRGRNLLRVQGDLLAAHSLNIR
NLFVVMGDPTRIGDFPDAHDHFDIPPSGLVRLIKQQLNRGVDQAGHSIGAPTRFFVGAAV
NLGAENLEREMKVLRRKLDGGADFLLSQPIFDPKVVERFYAAWGGPLPVPLIAGLLPLAS
SRHAE
>A0A2E9LUL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadetes bacterium|TrEMBL
MKSMIEDGLVHIFDGAMGSVLYTRGVFVNICFDELNLXNPEIVRRIHQEYVSAGSEIXET
NTFGANPVKLSSXXLXXRTEEINXKAAHLARDAGAGRVAVVGAIGPLGIRIEPWGPTAXA
EATAFFERQVNGLLAGGVDGXILETFADLNEIDXAFTAXRXXGDLPVIAQMTLGQNGKTX
YGHTASQIAQELTSIGXDVIGLNCSVGPAVMLDAIEDMADTTXVPLSAQPNAGLPRTVRD
RKIYMATPEYMAQYARRMVDAGXRFVGGCCGTTPDXIKQIRXXVRSDQPXPVXVRVTDVG
DQXXXAXXDXVPLEACSAWGRKLSRGEPVVSXEVLPPRGWDRNAIVXPAHELKDAGXDSL
AIVDGPRSRSRMGALSAAVIXEQEVGIEAIVHYTCRDRNMLGMISDLLGAAAXGIRNLLV
VSGDPSVHGPYPDMTEVFDIDSIGLTNVVTGLNQGXDPAGNSIGXPTKFVQGVVAXPGAL
DLXREVTRFRYXVEAGASFVVTXPIFXPESLEXFLDKIHQWKIPVVAGIWPFLNLRNAEF
LANXVPGXTVPEKIVDRMRKAQISGDEEALNEGVEIAAEMIDAVRPLVQGFHXXAPSRRV
DVALRVLXEAGVSTNX
>A0A7Y1ZJI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halioglobus sp|TrEMBL
MPATKPRISFEFFPPKTDAGTDKLLNEVRPALSELSPEFFSVTYGAGGSTRDSTLGVVSA
IREKEVAVAPHLSFGGSDENAVGDLLEQYRDIGINRIVALRGDRPSGMGGATLVYANELV
EFIRQRCGDHFHLEVAAYPEIHPEANGYDSDVRFLKSKFDSGADSAITQFFYTVEAYFYF
LDQCAAAGIDKPIYAGIMPLANFANIRRFAGNTGAEIPRWICQRMDSYGDDPESQYQFGL
EVVTQLCQTLLDSDCPGIHFYTMNQVEPTRQIHSNLGL
>A0A846E5R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphaerospermopsis sp. SIO1G1|TrEMBL
MQDSHSTSALNNFRKAVVAGDFLVTAEVAPPKGGDPSHMIEMTATLKGRVHAVNITDGSR
AVLGMSSLAASVILSQQGIEPICQIACRDRNKIGIQADLMGAHALGIRNVLALTGDPVKA
GDHPDAKPVFDLESIRLLRLIRNMNEGFNYNQKSLKDGALDIFPGAAVDPQLKSWSGLQS
RFAKKVEAGAQFFQSQLVTDFEKFEKFMAQIASEYNKPVLAGIFLFKSAKNADFIKRMVP
GVHIPDQIIDRLAKAEHPIQEGMKIAAEQVKIAKDLCQGVHIMAVKREDLIAPILDLAGV
GKVN
>A0A1Q3W0Q3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Afipia sp. 64-13|TrEMBL
MSETASIVPAGEARRPSISFEFFPPKTAEMEQNLWNVIERLAPLAPDFVSVTYGAGGSTR
ERTHSTIARILNETSLTPAAHLTCVDAARGDIDEVVDRYHEVGVRHIVALRGDPSGGIGT
AYQAHPQGYQNSADLVASIKRRHPDMEVSVSAYPEKHPESASLDADIDVLKAKVDAGATR
AITQFFFDNDLYFRYLDRVRAAGIDIPIVPGILPVQNFKLAKNFATRAGATVPDWLAAKF
DGLDDDADTRRLVAATVAAGQVQKLSKHGVQHFHFYTMNRADLVFAISHILGIRPNGAQK
AA
>A0A4Q1AB36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp. CECT 8986|TrEMBL
MFKNLIQKLQEDKYLTLETTPQHEPTMHNIIERIKKFDLQHRVDGFSATDNPLAKLKYNA
LFASMKLQQEFNKPVIATMSMRDRNKIALQADLLGANEFDVRAILALTGDPAKMSDQPHA
KGVFESNSSMLLKIIKSFNYGMDIAGHPFKIEPKQIYPFAVTNAYARSFSSLQKKMHNKV
QNGAVGIITQPVFEIDNAKKLLEIFNEAKEDVVGNKKKAQLIFGIFPITKLRTALFLSAQ
VPGIHVPQEWIDKLELANQISPEEEYKVGMQLSKDLFTSIKKLHPKIHLMTANKFDLADE
ILS
>A0A1Q7FE42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium 13_1_40CM_65_17|TrEMBL
MHIAEMLDRGRPTVSFEFMAPRDENEVQVLEKTVAALAGHAPDWVSVTYRLRTGQETLEL
VTRIKRQYHIEAMAHLTCANTRDATRRILNWMEREGIANVLALRGDPPGPGQPFQPADAG
LTHGSDLVAFVRGNGYRLGIGAACSAEKHPESPDLEHEFHYMRLKVEAGADFLITQLFFD
NRFYFALVARARTAGIKVPIVPGLMPLPSRRSLAFVTEMSGASVPEPLQRAIDAQPDDEG
IRKLGVEHCIRQCVELLEAGVPGLHFYTFNRARAPIEILGALRGQQLLAS
>A0A4R2IST6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinocrispum wychmicini|TrEMBL
MTSVLERISVDRVVFSVEFMPPRDDADEQQLWRAIRELEGLDPAFLSVTYGAGGSRRDRT
IRTTGRVARETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVHNVLALRGDPPGDPMGEWV
KHPQGLSYADELVRLVRELGDFCVGVAAFPYGHPRCADLDTDADMLVRKFRAGADFAVGQ
LCYDAADFLRLRDRVAARGSDAPILPGVMPLTTPKMLGKTLELSGAPVPPKVAERLEPLV
DDPKSFRAAGIDVVTEMCEQLIAEGVNVLHFYTFNRSKATKEVLGRLGLVASRTP
>A0A0N0GPZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amantichitinum ursilacus|TrEMBL
MTQPQPLSFEFFPPKTAEGAEKLRITRRQLAQFKPEYCSVTFGAGGSTQDGTLTAVLEIQ
SEGLAAAPHLSCIGSSRVRISEILQQYRASGIRHVVALRGDIPSGMLDVGEFRYANELVA
FIREQHGDWFHIEVAAYPEYHPQSNSAEADLRAFVNKVNAGADAAITQYFFNPDAYFHFV
DEVRARGVTIPIVPGIMPIQNFNQLSRFSDMCGAEIPRWLRLRLQSFGDDTASIRAFGLD
YVTELCDKLLDNGAPGLHFYTLNAAGAVSTVCQRLGR
>A0A4Q8T9R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. KUL17|TrEMBL
MVSYAQGIDALNQSLSELRDIDVSFEFFPPKTEAMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGATEAIT
QFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVKFAGFTNVHVPGWLHKMFDGL
DADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRSGA
>A0A1Y2SBC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenorhabdus vietnamensis|TrEMBL
MSFFHANQREALNQNLAELEGQIRVSFEFFPPRTAEMEQTLWKSIDRLSKLKPKFVSVTY
GANSGERDRTHSIIKGIKEKTGLDAAPHLTCIDASRGELSNIAHDYWQNGIRHIVALRGD
LPANGCKPEMYGADLVELLKKEADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFRQLQRFATITNVRIPSWMTRMFE
GLDNDPESRSLVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPS
>A0A370LB78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea caraganae|TrEMBL
MNAFRPSRHGSRRPRVSFEFFPPKTPEMELALWESVRRLEPLKPSFVSVTYGAGGSTRER
THNTVKRMVEETGLKPAAHLTCVSASCAEVDEVIRSYWSAGVRHIVALRGDPAGGLGTTY
EPHPQGYHQTSDLVAGIRKIGDFEITVSAYPEKHPEAGSLDADIDALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRARGIDIPILPGIVPVQNFKQTANFASRTGASVPQWLADRFEGL
EDDVATRRLVAAAVCAEQVLDLIDRGVSDLHFYTMNKADLVYAICHLVGLKPDKNVQQQA
AAE
>A0A4Q9HHN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter kyonggii|TrEMBL
MKITDHIKNAKGKTLFSFELLPPIKGQSIQWIYDAIEPLLEFNPPFIDVTSLREDYIYKE
QANGLLQKVSYRKRPGTIAICAAIIHKYKVDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARKADGNFVPTPGGHCYATDLIEHIKNHNEGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNMSTDFKFLKKKVEAGAEFIVTQMFFDNQKYFDFVKKCRENDINIPIIPGLKP
ISTLSQLNVLPKIFHIDLPDELTDALSHAKNNNEAKEIGTEAMIKQCKELIDFGAPVLHF
YTMGRPEQTKKIAKAIF
>A0A7C4GM91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Korarchaeota archaeon|TrEMBL
MEIGIEIVPSNLPRFLRSLSSVIGYADFISLPECPFGRPLPSPLVFSVIAKGLGLEAIPN
YRVMDRSELGFISEMMALSEVGVRRIVIVRGDLPSIGMPTHLNPVRAIELIKEHGIDIDV
GVATYVKPSETLRAKIEAGADFVITQPIQDVEELSELLDFLGDIPLYTMIMPGLEDLDPN
VLKEMGLKEVRNVDYKALLQDISRTKVRGVIISSPKGVSKALEILR
>A0A7C1DIX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MTFREKLDSNRFVVCGEMGPPQSPNGDVIRKKSAHFRGCVDAVNITDNQTAIVRMSSIAS
AKILLDEGVEPIIQMTCRDR
>A0A7K8Y3P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubucco bourcierii|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTRDDITRHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAADL
VKHIRNEFDDYFDICVAGYPTGHPEAESYEEDLKYLKEKVFAGADFIITQLFFRSETFFK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTCEESVFEVFTSYITGEPNKNGYKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYESRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A093QLD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phalacrocorax carbo|TrEMBL
MVNETQQTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDTDRHERLRDKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDEYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFVITQLFFSSACVTG
MSEKGLGKTKIPCILIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAV
SMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRRVEDVR
PIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGE
ELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRGILTIN
SQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYDLRVNYHIVNV
KGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEES
PSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A3A8GPN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corallococcus sp. AB011P|TrEMBL
MKIRNCLNPSKPSFSFEFFPPKTDAGVASLLRTLEELAPLEPGFVSVTYGAGGSTRDRTV
DLVTHIKQQTGIEAMAHLTCVGHTRDELRDVLRRLDAAGIENVLLLRGDPPQGQTAFEPV
PGGFRYAEELVRFVREEDFNFCLGGACYPEGHVETASREDDLKHLKAKVDAGMDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNYEQVQRFTRMCGATVPMRLALQMERVKD
QPDAVVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVGALKGRS
>A0A2S5VZU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Subtercola sp. Z020|TrEMBL
MQRAAPQPGETVLTRLRFEVIPGDENHASPTGASLADRLLRAFPAPTGVTLTVTSLPQHG
VERTLRSAVELAGLGFRVVPHLPARGIADRAALEDMVRRMLGAGITEVFTVSGDAAPGSG
GGTGAYSTSLELIRDLADIAPELSIGIAGYPEGHPHFSDDHLLQHLRERAPYIDTIVTQL
CYSPQAVARYAAMLRRIGVEAELWVGVPGPIGLARLETLSDRLGVGRSKELLGRTGADGA
GFDAAGFDGAGFDGAGFDAARFDAARFDAAGFLRAVEAQPELADADARDHLAGAHVYTFN
EIEGLPAFVEAVTVNHA
>A0A4Q0YZI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp. F155|TrEMBL
MLTDKIRNKENGILLYGITPPKVKHTEEEIKEIAKKHVERISSLNVDGLVLYDIQDESDR
TDEKRPFPFIKTINPCEYSKNYLQDLKTPRIVYRAVGNYTAKQFATWLESTKATQVHSVF
VGAASHEQQTNITLKEAYGIKKEVNDNLCLGGIAIPERHMKKHDEHLRVFSKQNSSCEYF
ITQCVYDVHAAKTFLTDYAKYAKENNIEPVPIIFTLTPCGSSKTLDFMKWLGINIPNYLE
EDLKESGDILHDSVKLSRDIFEDLFKYGKKRGIPVGCNIESVAIRKAEIDASVELLEEIR
QIIKDNK
>S2ZUN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium pyruviciproducens ATCC BAA-1742|TrEMBL
MKTTELFKRKTVFSLEIFPPKKTASIATVYDTLDGLEGIHPDFISVTFGAVGAGDNTHTF
PIASTVKKYYQIEGVAHLPAIGLTRDQVRERLDEMKARGIDNVLALRGDLPAGGEQPTGH
FPHASDLIAFIREYSDLNIIAACYPETHPECPSRVDDIRNLKRKVDAGASHLISQLFFDN
SRFYGFLERCDLAGIDVPIEAGIMPVVNKTQIERITSLCGAEIPHKFRVMMDRFGDNPRA
MRDAGIAYAIDQIIDLITQGVDGIHLYTMNNPYIARRINDAVSTLIANTPPRAAHRKVFA
LA
>A0A2P9GYT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacter sp. SbD2|TrEMBL
MSVLRSGSNLEKVLKAGHFALTGECGPPKGANVEHLKEKGTHLVGIVDCVNVTDNQTAVV
RMSSWAASLILMQIGLEPNFQMVCRDRNRMAMQSDILGVYSHGVRNILCLSGDHQKFGNH
PESKNVFDLDSMQLIHLVRTMRDDGKFLNGEDIDVRPKLFIGAAANPFAEPCEFRVHRLA
KKIAAGADFIQTQCIYNMERFREFMKQAVDMGLHEKCYILAGLTPLKTLGMARYMAKSVP
GMDVPDSLIQRLEGAGKGKVAEEGIKITLEQIEEFKEMEGIAGIHLMAIEWEHRVPEIAE
RAGLLPRPKV
>A0A2E0CBM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MIKKKFIKSIEIIPSRYKIDNLLLNQILKSNKSFDLLDIACAPMANLRISPISYAHKLIL
KGINPKKMIINFSTRDKNTLALQSEILGAASMGISNLLLVKGDPISIGNSRKSKEVFELK
TNELISLVNNLNKGIDYSGNLINFNPKFTIGSTLNIDLPLKNIQRTLIKREKIGSDFLIT
QPLYSEEDFVNLSKLSKFSKCKIFAGIFPIKNKKTFKNLNSKIDGINRNNILFDELKKSD
EKDFLKISSKYLIKLLKKYKKDLHGVHIMTAGDISLASKISNEV
>A0A1E4JRN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingopyxis sp. SCN 67-31|TrEMBL
MTSNLNSLAEARRAAASPLFANLDGDIGVSFEFFPPKTEKMEAQLWDTFRTLEPLGPRFV
SVTYGAGGSTRERTHATVARIAAESAVPPAAHLTCVEASREEIDAVARAYWEAGVRHIVA
LRGDVPGGAPYRAHAQGYANAAELVAGLKAVAPFDISVAAYPEVHPDADCAQTDLDNLKR
KLDAGATRAITQFFFSPEAFLRFRDAAAAAGIDAPIVPGILPVSNVSQTRRMADMCGAAI
PAWMVSLFEGLDDLPSARQLVAATIAAELCRRLYAGGVRDFHFYTLNRAELSYAICHLLG
LRPPAAPAAEKAA
>A0A3A0FJE8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium|TrEMBL
MRFADRLRSGQFAVALEITPPQRPLQSVLLRRASALGHCADAVNVIQRPGRQSSLDASIS
LLRTGIEPVWHLVTRGASRGDIARDLVSAREAGIGQILVIRGDHATHDLPDTPAIREAIG
LAREALPGALIGATFNQYAPDPGAALRNLLPKLRAGADFIQTQPVFDPQALAPFVQRLRD
ECPGVAFVPMVVPLLSPAAVDGIQRRLGFRLPEQLARRLAGGPESGWEVLSETIAGLVAS
PLADGAAIMTTEMDPPPAVGERIVSALRAAGIDC
>A0A2W2EGP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea aridisoli|TrEMBL
MALGRPSIRPDRVPTVRELLASGGRSFSFEFFPPKTDEGARQLWRAIRELESLRPTFVSV
TYGAGGSTRDRTVDIVERIAHDTTLTPVAHFTAVNHSVRELRHLVGRFADAGVRNILAVR
GDPPGDPMAEWVPHPEGVLYAEELVRLIRQAGDFCVGVAAFPYKHPRSPSIESDTEYFVR
KCEAGADYAITQMFFEADDYLRLRDRVAARGCETPIIPCVMPVTQMSTIARSEQLSGAPF
PAGLAARFEEVKDDPAAVRRLGIDHGAEMCQRLLDEGAPGIHFITFNRSSASREVFQRLE
RVPLSA
>A0A1V5GIB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium ADurb.BinA245|TrEMBL
MKVTDHIAQAKDTLISFEVLPPLKGKGIEALYKHLDPLMEHKPSFINVTYHRSEHVFKKK
IDGSFEKVVVRKRPGTESICAAIMNKYNVDTVPHLICGGFSINDTEDALINLRYLGIDNV
LVLRGDAAKNETAFEPEPGGHKYANELLKQVADLNAGIYLEENLKNSHKTDFCIGVAGYP
EKHFEAPNMDTDLQYLKAKVDAGADYIITQMFFDNAKFYAFVDACRMVGITVPIIPGLKP
IYNKKQLTVLPKTFHIDLPADLSNEILKCKTDDEVEKLGQEWLLAQSRDLKKNGVPVLHY
YTLGRPHVVANVVRDL
>A0A0A1W4F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas parapaucimobilis NBRC 15100|TrEMBL
MTNTILTRAEAALAHEEPLFADVGGDIAVSFEFFPPKTEKMDTQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTMDAAAHLTCVEATREEIDQVAHEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPDSVDRASDIDNLK
RKIDAGATRAITQFFFSPEAYFRFRDAAAAAGITAEIVPGILPVSNVAQTRKFAAMCGAR
IPDWMDRLFEGLDDHPGARQLVAATIAAEMCRRLYAGGVKGFHFYTLNRAELAYAISHLL
GVRGKKAEAVVAA
>A0A537H5B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MTCRDFRRSDLSLLPGLFKKGLENFLVVFGDPYPNYDLKRYDFKRTEDLIDGIRSVFEGP
RPCIGAVTNQYALNREKEITRALSKVDAGADYVVTNSAFDDYYVLDYIDALRSGGLKVPV
FVQLSIPHGLNNLLFVSRRFGIPVPESVKETVSRNPLGGGVQVIARAFAGLRNEVSGIHF
SYLFRSHNPIPTYTHLLDAIETDWQLVGSLL
>A0A7S7SRJ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia sp. UMI-21|TrEMBL
METPNFSIEFFPPKTDEGAEKLRVVRQKLAELRPKYFSVTFGAGGTTQQGTLQTVLEIQS
EGIDAAPHLSCVGGTRDSLRAILQQFQDKGIRRLVALRGDLPSGYGGGGEFRYANELVEF
IRKETGDWFHIEVAAYPEMHPQARSPQDDLQAFARKVQAGANAAITQYFYNADAYFDFVD
NARKLGVDVPVVPGIMPITNYTQLMRFSDMCGAEIPRWVRNKLASFGDDSASIKAFGLDV
VTSLCERLLAGGAPGLHFYSMNQAVATTAIWQRLVK
>A0A6G6F312|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium SC52|TrEMBL
MTTPRISFEFFPPKSLDASFKLSETVRMLAPLDPGFVSVTYGAGGTTRKLTHEAVVAIHK
NYGLNVAAHLTCVDASRAETLEIAESYAAAGVTELVALRGDPPKGSGGFVPHPQGFNNSI
ELIEALAETGKFKLRVGAYPDPHPEAVSANADVEYLKRKIDAGAHSAITQFFFGAETFFR
FRDRCAAAGITAPIIPGIVPIDNWKGVRKFAVACGTVIPPEVDAAYETAIRDGREADLSI
AMCTELCSDLMEGGVEDLHFYTLNKPNLTRDICHALGVTQAATLENVA
>A0A8J3D2I6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Persicitalea jodogahamensis|TrEMBL
MTKVTEHIQRSEGQTLFSIEIIPPLKGQNINQLLDSIEPLMEFKPPFVDVTYHREEVIDK
PQPNGLVQRIPVRKRPGTVGICARLMERFKVDAVPHVICGGFTKEETEDMLFDLHYLGID
NALILRGDPEKSAGVFRAKTGGHAYASELISQVRDMNRGVLLHEETEATPTNFCIGVAGY
PEKHFEAANYDTDLSYLKKKVEAGAEYIVTQMFFDNQKYFQFVERCRAAGITVPIIPGLK
PLATRNQLTVLPRIFHLDMPQELVQEAEKCATNDQVRQVGIEWGIKQCKELIEFGVPVLH
FYTMGKSDNVMQIARGVF
>A0A497N319|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
TQVCYDINKTLKFLRMFKIFKIPILVGIFPMKNYGTANFFNAYVPGVSVPKDLMEKFVEV
KKGGYSKKEKREKYDQINLDFFVPFVKELMKSKLCAGCHIMSVHYTEMIPKLLKEVQPIP
EPAISVVSK
>A0A419JRZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MATQTVSNLMADLKDGKFVFTGELEPEKTTTLEHALEAARKLKGYVVACNVTDNPQSFAY
ISSLAASYLIQQKVEMEVIYQITCRDRNRIALFSDLLGAGALGIKNVLALTGDHPTLGDT
PQAKPVFDLDSVQLLYLIRKMVDEGKDLNDNPIESPPQFFVGAGANPNADPIEPELIKCA
KKVQAGAQFFQTQVVFDLDIAKNFLKETSRYNVPVLIGIFPLRSYGVAEYFDKNVPGVKV
PEELLEALKKAKKTPDKKERKQKYNEINLNYFANFIKELKKTTSAAGCHVMSVGYESIIP
SLAEMVK
>A0A497KS83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MKRIREGKFVVTGEVEPVKTTDLTEVLEAAKRLKDCCVAVNVTDNPTAFGYMNALVPSYM
IQKEVGLEAVYQMVTRDRNRLALLSDLLAAGALGLKNNIDLTWDSV
>A0A497N0J6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MAERVYSNLMRELKAGKFVFTGELEPGKEGSIEGTIEAARKLLGHVTACNVTDNPQSFGC
VDSLAAAHKIQAETGMECICQLRCSDKNRLALLSSVLAAGVLGIKNILAITGDYVSLGDT
PDVKPVYDLDATLLTRMIRRVVDEGKDLRGGEIRNPPKLHVGVAANPGSAFLDMEVYKLK
RKVLAGAEFVQTQVVYLPEVVDNFFAKVKE
>A0A497ERL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Verstraetearchaeota archaeon|TrEMBL
MITAKRKPISEILSMVEGHKNVLLLACDGCVGIYDVGGLKQAEALKLELELAFRSKGKEP
PNFTTATVLRQCDTEILKDSISEHVAKIDAVLSLACGVGVQTVAHVFSEAHVYPANNTAF
LAMEDKKEGMLREWCMACGNCVLHLTGGICPIARCAKSLLNGPCGGFYQGKCEVDGRTRD
CAWVLIFNKLKERGKLDLFTAIRLPKDYRDVKNPRELKREELVLPEAKEAIKILEEVEVK
KRPAYSQLMKELSEGRFVVTGELEPVKTTDLTEVIEGAKLLRDYVVAINITDNPTAFAYL
NALVPSYIIQEKAGVEAVYQMVTRDRNRLALTADLLAAGALGIKNILALAGDFTTVGDNP
QAKKVWDIDSTLLIYLISRMVDEGVDLAGNPIHNPPKFNIGAAANPNADPLEPELYKLLR
KQKAGVDFLQTQSMYDIEKIKRFLDECRSIGIKVPILIGITPFKSIKMMEWFVKNVPGVY
VPEEMQERLRKARDRGKEAFMEENIIVFGELCKEIRKTTSAAGIHMMAVGMESLVPRILE
MAGIGKYRSS
>A0A7S9WWG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter concisus|TrEMBL
MLKEKILNKEKGLVLYGLTPPKAEFEEAKLREISERWSGRINDIKADGLVLYEVQDESER
NDSERTFEFSGTLSPEIYYKKYLNVATPSIFYRVASGYGEDDFRAALKAQSSNLNVLVGA
TSSTQKVRLNLARAYEIASEFKELAVGGVCIAERHAKKGDEPQRMREKIAVGAKFFISQA
IFDVQLARKFLEDCAAAKISEPIFLTFSTAGNAKTLEFIKWLGVSVPSSVEERLNLSSDY
LASSCEIIKEIWCELKKFGDENGLNLSINIESVMAKRAEIEASLELTKSIRELV
>A0A7J3FA24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MSKIFISELMANLKSGKFIFTGELEPEKTTDLTAYVDVAKRIKSYVVACNITDNPQSFAY
ISSLVASYIVQKESGLEVIYQITCRDRNRIAIFSDLLGAGALGIRNVLALTGDYTTLGDT
PQAKPVFDLDSVQLIHIIRRMVDKGVDLNDKPIESPPKFFIGAGANPNANPIEPELIKFE
KKVHAGADFFQTQVVFDIEKAKSFLEETKRYNVPVIIGIFPLKSYGVAKYFDENVPGVKV
PEDLMEALVKASETSDKEIRKAKYMEINLEYFSRFIKELKKTTSAAGCHIMSVGYEEIIP
PLVDAVK
>A0A497JUS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Bathyarchaeota archaeon|TrEMBL
MGKKRPAYSNLMKEIEASRFVLTGELEPEKTTSLEEVLASARAMKPYVVAANVTDNPLAM
AFMNSLVPSYIVQRDVGLETVYQMVIRDRNRLALTSDVLAAAHLGIKNILAISGDHTVLG
DNKGGLPVYDLDSAQFVYLLHKMIDEGTDLEGNEIHGEVPINVAIAANPNANPLEPEILK
IGRKVKLGTDFIQTQTMFDIDLTKEFLKETEKFNCPTLVGVFPLKSFGIADFFDKYIPGV
SVPKDLLDSLRKCKEEPDKEKRKPLYDEVNMEFFAPFIKEIKKTTKAAGVHVMAVLYERI
LEPLLA
>A0A1I5U5I8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas rubra|TrEMBL
MTISVDQLAEARCALESPLYADVGGDLEVSFEFFPPKNEKMDAQLWDAVRTLEPLGPRFV
SVTYGAGGSTRERTHATVARIQRETSMAAAAHLTCVEATKAEIDAIAEEYWAAGVRHIVA
LRGDPPTAGAKYASHPGGYENAADLVAGLKRLHPFEVSVSAYPECHPDSGDAAADLDNLK
RKLDAGANRAITQFFFEPETFFRYRDQLAAAGIDAEIVPGIMPVMNFASVQRMSAMCGTA
VPPWMARLFEGLDDHPAARQLVAATVAAELSRRLYAGGVKQLHFYTLNRAELAYAICHLL
GVRAKVPAAVAAA
>A0A1J5VET3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. NML140438|TrEMBL
MRQATLETRISASAPLDGSEEELAPRPQRARTALSFEVIPPRHDADSAKLDALIQGLAAY
QPDYVSVTSSHRSDWLEGTARLIERIAQTTSMRPIAHLACTAGTPAELEQWITQLIDAGV
RGFLALRGDIPAGLDRLPDTHLQYATDLLNLIQDVADAQAYRLAAGKLALSVACYPRGHS
ESTSFDQDLDVLLAKRRLGADFAITQLFFDAQDYLSFAERARLAGVRIPLIPGIMPMTSV
NRVRRMGELSGVAPPVDVIKQLEAARTPEEEHQIGMRLTVELARTILQAGAGGLHVYTHN
DLAVTRELLKGLNL
>A0A353K459|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp|TrEMBL
MTGAADEGLRAALTRSTPTFSFEFFPPRTAAGGRALWNAIRRIEPLAPDFVSITYGAGGS
SRDRTVEVIGRVVTETTLRPVAHLTAVGHSAAELRRVVGRYADAGVRDVLAVRGDPPGDP
RGAWSAHPDGFTHAYELVELIRSLGDFTIGVAAFPERHPRSSDWESDIRHFVAKCRAGAD
YAITQMFFDVEDYLRLRDRVTAAGCDTPIIPEIMPATDVRRISRFAELSGCAFPEDLAHA
LEAARDDPAAGHRIGVEHATAMAERLLAEGAPGLHYITLNSSTAATDIHRAVAPAWTVPP
AGTGAVRGAVPAGGAPVGLPGQA
>A0A1G0I2Q9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_63_22|TrEMBL
MIPLSFEFYPPKTDEQRTQLDRTVRKLKAHSPQFVSVTFGAGGSTLSYTPETVRDLRQAH
KLNGVPHVSCMGGTREEISSLLQLYRALGCDRIVALRGDLPSGMARMGDLRYATDLVEFI
RAEHGDHFRIEVGCYPETHPQAEDALADLRHFKAKVDAGAHSAITQYFYNADAYFRFVDD
ARKMGIDVPIIPGIMPISNFTQLKRFSEACGAEIPRWISKRMAALGDDADGIRELAADLV
AAMCRRLVAAGVPELHFYTLNLSKPTEAVIARL
>A0A3D2XBG2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnoclostridium phytofermentans|TrEMBL
MQISKKFGQGKTVFSLEVFPPKKDSPVESIYRVLGELTKLKPDFISVTYGAGGNAADHTT
CDIASYIQTNYGIDALTHLTCVNSTKEDMDTTLEYLKNQGVMNILALRGDKNPEIEPKKD
FTYASSLVEYIKTKGDFHLSGACYPEIHIEASSMEEDLEHLKYKVDCGAEHLISQLFFDN
DYFFDFLEKARKKGITVPIEAGIMPVVNKRQIERMVTMCGASIPSKLAKILQRYEHQEEA
LRDAGIAYAVEQIMHLVASGVDGIHLYTMNNAYIATKIHEAIFRLL
>A0A2D5IGG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinovum sp|TrEMBL
MQQPQISFEFFPPHTIEASFKLKDTIQILAPFSPRFVSVTYGAGGTTRELTHQAIKALRG
STDLNVAAHLTCVNVSRKRTLQIADQFAADGVTELVALRGDPPKGSSAFKPHHDGFKNTC
ELIHALADTEKFFIRVGAYPHKHPEASSSEQDILWLKRKFDAGAKEAITQFFFEADDFFR
FRDACVKAGIQAPIIPGILPIENWAGTRKFAQKCHANIPVWLDDAFTKAERDGRNDLLAT
AVCSELCSDLIEGGVDAMHFYTLNRPELTRDICFSLGIFPAATLENVA
>A0A0Q6RR39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. Root1204|TrEMBL
MAIHTLYPAERGNLRLSFEYFPPKNDDMETHLFQTVADLSAFDPAFVTMTYGAGGSTKAR
SLTAVQRMIHDEGFANTAAHLTCVGATKPEVDAIVDEFIGNGVRHFVALRGDPQGGIGAR
YEPFPDGYENAAALVAAIRQKGDFEISVSAYPEKHPESPDVDADIDMLKRKVDNGATRAL
TQFFFDNNDFERYLERVRRAGITIPVVPGIMPINNLAGITKFAGLCGARVPEAIITRLIH
LDESPEERFKEATHIAAEQIVDLARRGLRDFHLYTMNRSPLVTAVCDLVGFERVVPAAVP
SRSAGAAA
>A0A1V2NM02|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium sp. CSI-V|TrEMBL
MTLLPLLDACPKRMEYGPCGGVGFDGSCEIDAEHTCAFLPRGTVPWTGVDRVSAPAPGPR
SAAAAETLASLGTRPWVVADLPARALSVASIDSCAAVLAGEVDAVLAGDAGTARVQFPPA
YRAHLLQRAGLRVWTGLNMRDRNRVAIEGELAALAVEGVAGVHCVTGDHTRTGHRPDAAP
VFDLDSTEAAALARAAGHVVSVAASPVAPPVERRAARLREKLRAGADVCFVNHAGGAEPV
RRFIDSVAAPVRFIPCVPVVVDHASADVLESFTTLAVPDGFLARIRGAADPRAEGIALAV
ALAEEMLAIPGVVGVNLSGGRDGGEESFAEAQAEIARRLR
>A0A2W4MAF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MENRFKESLLNKNEFTITWEIVPGRGAREKSQEEVIEAAEAAAKSGKIHALTLTDNPGGN
PAILADYLATEVLAKGIEPLVHFTCKDRNRNQIESQLYALDRAGVRNLLIMTGDYTVTGY
SGRPKPVYDLDPIHVLDLISKMNQGLEYPGMKGKTIKHQPSDFFAGAVVSPFKATEAEQM
VQYYKLKKKVKAGAQFIITQLGYDARKFHEVLQFIRQQGWDIPVIGNIYILPLGTAKAMN
KNRIPGCVVTDKLVAQLEQEAQAPDKGYQARLDRAAKMYAFMKGMGFDGVHIGGHGVKFE
DVEYIIEKGEEFSKNWLDYIHEFDFPIPGGFYYYEKDPKTGLNTPNPVDRKNRPLDAPVE
FAYRLSTFTHRLMLEPGTPLWGPMRAIAKMVDGTSLERPYHAFEHLMKVCLYDCHDCGDC
ALVDVAYVCPMSQCPKYQRNGACGGSYMGWCEVYPNKKKCAWVRAYARLKRYGKEHELEE
RIVPPPNHDFQQTSSWLNYYLGRDHSASRFGIERYEKKKK
>A0A7I8MTB1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis associated proteobacterium Delta 3|TrEMBL
MSTDNGYKSGSNLEKVLKAGHFAFTGELGPPRGTGAEEVLEKAQHLKGVVDAVNITDNQT
AVVRMSSWAASLLLVQEGLEPNFQMVCRDRNRLAMQGDILGVYTHGVRNMLCLSGDHAKF
GDHPDAKGVFDIDSMQLIAMVKQMRDEGKFLGGADIEHPPKIFIGAAANPFAEPYDWRPH
RLSKKIDAGVDFIQTQCIYNMDRFREFIKVANDMGLTEKCYILAGVTPMKSVGMAKYMKN
KVPGMDVPDDTIKRLQGAEKGKVAAEGIKMACEQIEEFKEMDGVHGVHLMAIEWEHKVPE
IAEQAKVLPRPQVD
>A0A6N8B950|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MKSCSGLEKVLTEGRFAVTAEIGPPKHASAEKIIEYAKMLKGWVDAVNITDNQTAIVRLS
SIAAGVHLYNNGVEPVIQVTCRDRNRIAMQSDLMGAYSLGMCNVLCLSGDHQKFGNHPQA
KNVYDVDSIQLIDMVRGMRDDKKFQCGEDIKEHQPKYFIGAVANPFADPFEFRVLRLEKK
INAGADFIQTQSIFDMNRFEKFMNMVRQRGLHKKVHILAGVTPLKSARAARFIQKNVAGM
IVPDEVIERMEKVEDQKGEGIKIATEQIQQLKKIEGVAGVHIMAINWEDMVPEIVEKAGL
KNY
>A0A7C6SZX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MVLLARLYNKLMSGQFAVTVEMDPPKGADPRKTLEKVRKFSDRVDAVNVADCPMANVRMS
PITVAHLIQRDANVEAIFHLTCRDRNVIGLQAELLGAAGLGVRNILALRGDEPTRGDHPE
ARGVFEVDTPGLIRLAAELNHSRTVAGSGLERGTELAIGCAANPTARDLEFEVSRLEAKI
EAGAHFVQTQPLFDLRDLERWLTKIQGRIKVPILYGVMPLKNYNFAVHLNNNVPGIDVPS
WIVDRLRNGAKGEGIRIAAELIKSMAPLVSGVHIFPMNSPERVVALLQALDETRGFEKEA
VAGGAR
>A0A7C3QWS4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MKGKDMVGNDLDGIPAFFLGAVVSPGYEPQELQLLKMERKIEAGARFFQTQAVYDLDAFE
KFMKQASNFGVPVLGGIVLLKSAAMAKFMNENVAGVSVPERYINMMASADKKDRPKVSVQ
IASELIKGMKGLCSGIHIMPLGWERYVPDVLEASGF
>A0A268E691|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. 7586-K|TrEMBL
MSFLEDLKSKILIGDGAMGTMLYAHGVDRCFEELNLSKPSDVLRVHEAYIQAGANLIQTN
TYGANDIKLSRYGLEDDIRQINKQAVEIAKQAVKAAIAPTYVFGTIGGIRSFKKSAQSLD
DLKRNFREQLYVLLNENVDGILLETYYDLEEMTTVLKIARKETNKPIIANVSLHEAGVLQ
DGTPLQQAFTTLEELGANVIGLNCRLGPYHMIQSLEEVPIPKHAALSVFPNSSLPALNEG
RLVYESDEGYFKESALKFREQGASLIGGCCGTTPRHIQAMAEAIAGLEPITSKKVRAPKE
IQDSITVTSPNSLPPLQEIVTDRRSVIVELDPPKKLGMSKFLEGAKALHNAGIDALTLAD
NSLASPRVSNLAAGILAREKTGTRALIHITCRDRNLIGLQSHLMGLHSLGLSDVLAITGD
PSKIGDFPGATSVYDVSSFDLISLIKQFNAGVSYSGKPLGEKTNFSVAAAFNPNVRHLDK
AVVRLEKKIACGADYFISQPLYSTEQIVEVYKATRNLKAPIYIGIMPLTSSRNAEFIHNE
IPGIKLSDSIREKMAAAGTHKDKARLEGLAIAKELIDAAFDLFNGIYLITPFLQYDLTVE
LTNYIHEKEKQLAERKITHV
>A0A8H7QNE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor plumbeus|TrEMBL
MKVVDKINKAQNEGRTYYSFEYFPPKTEMGVQNLYDRMERMQRFGPEFVDVTWGAGGTSA
DLTMDIVATSQSVYGLETMMHLTCTNMPVESIDTALKAAKACGCQNILALRGDPPKGQLN
WESCENGFNHAVDLVRYIRKNYGDYFCIAVAGHPEGHIDNEDKEDDLLRLKQKVDAGADL
IVTQLFFDVDVFIQFVKRCRDIGITCPILPGIFPIQSHAGLKRVISFNNNAVPQKLWDDL
ESIKDDDQAVKDYGIDLAVEYVNQIKKETGINGFHIYTFNLERSSRLILEKLGLVPEQEY
VKPLPWNPSLGPNRTKETVRPIFWKNRAQSYIQRTESWDEFPNGRWGDARSPAFGEFDRW
GVSIKYPVEKRLAMWGEPQTSDDIALLFAKYCKGKLEGLPWSAQKLEPETDTIKQRLAAI
NLLGYLTINSQPAVNGAKSNHPVYGWGPKNGYVYQKAYIEFFIPPSKFDELVKNIGTDPE
VTYFAVNKNGDLKTNTIDDEPNAVTWGVFPGKEIVQPTIVEPTAFMAWKDEAFGLWNEWA
HTYDRQSLAAEVILDIYENWYLVNIVHNDFQDENGIWRLFDLEIDGDLSKKLRRGSGPL
>A0A1M4XL17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alkalibacter saccharofermentans DSM 14828|TrEMBL
MANKKLSYKDAVLSKEHFSVTWELVPGRGSTEPAQDQVIETAKLAVDDPRINAFTITENP
SGKPAILPYPLAKQILDETGGETLIHFTCKDKNRNEIESQLHAMNRSGLKNLLIMTGDYT
TEGYAGRPKPVFDIDAVHTLKMIKKMNQGYEIPVRKGTKKLNETDYFTGAVVSPFKSTEP
EQMAQYYKMHQKVDNGASYLITQLGYDARKFDELRRYADRYELGVPLIGNIFVLSLPVAK
MMNKNLIPGCVVTDKMIRDMEDEKGKYPDNKKRQLLRAAKLYAVLKGLKYDGATIAGHGM
SYDDLCWILDKGEELLLDWQEIAKEFDYPMDNGFYYFEKDPATGLNTDVPVDRSKTGHKR
NSLFDRMFGLVHKLVFKESALFYPMVKFFAKKIDKNFLNKPFTWFEYYTKTFTNECRFCG
DCVMHEIGFQCPMSKCPKSQRNGACGGGRDGWCEVYPGKQKCIYVVMYEKLKAHEKEYTM
KLRYAPPCNWDLYKTSSWLNFFNERDYNYRKDE
>M3VIV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gordonia paraffinivorans NBRC 108238|TrEMBL
MRIALYTGRVTPTAPAPSIVERLSAPHRGPVPFSVEFMPPRDADGEARLWRAVRIFERLS
PAFVSMTYGAGGSTRDRTVRITGELAAQTTLLPVAHLTAVNHSVDELRALVGAYADQGIT
NLLALRGDPPGDPLGEWVKHPDGVEYAVELVRLIKDLGDFHVGVASFPEGHHRAIDLEHD
TANLVNKLRAGAEYSITQIFFDVEDYLRLRDRVSKADPEQGAKPIIPGIMPVTSLASIKR
MAYLSGSVIPPAVEERFAKAAGDGPEENREAVRAVGIDFATETAERLIAEGAPCLHFCSL
NFAKATTEVLGRLGVDVDAALHVPA
>A0A355GR96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MARLLNRLTQGQFVVTVEIDPPRGPDAAKTLEKVRGFADRVDAVNVADCPMANVRMSPIT
LAHLIQRDAGVEAIFHLTCRDRNTIGLQAELLGAAGLGVRNILALRGDEPTRGDHPSATG
VFEIGSSRLIKLASTLNAGSTIGGSGLDCGTDFTIGCVANPNAEDLEAEVDRLEAKIAAG
AHFAQTQPVFDLRILEHWLMKVAGRVRIPILYGVMPLRNYEFAVHLNNDVPGITVPEWAV
ERMRVRGPQAGMEMVREFISSAFAASEISGIHIFPMNNAARILKVVDIIDELGVRCQRKA
KPIRIETRD
>A6GU55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnobacter sp. MED105|TrEMBL
MLRPTTNSVNEYTMMNISFEFFPAKTDEGAEKLRATREKLSERKPEFFSVTFGAGGTTQD
GTLSTVLEIKAAGEEAAPHLSCVGSSKEKVAALLKQYKEHGIKRIVALRGDLPSGMLETG
SFRYASELVEFIRRETGDHFFIEVAAYPETHPQAKSPAADVDAFVHKVNCGANSAITQYF
FNLDAFLYFRDQVQHRISIPLIPGIMPVTNFSQLARFSDACGAEIPRWMRNRLQHFGDDR
ESIRAFGLEVVSNLCEQLIREGAPGLHFYTMNNAQPTLAILDQIGY
>A0A522GFI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiaceae bacterium|TrEMBL
MVPGSTSAKKTISLEFFPPRDIAAREKLVRTAKQLLALQPEYVSVTFGAGGSTRSGTIDT
VHIMQNLGLEVAPHLSCIGASRAMLREVLDTYRENGVRRIVALRGDVPSGMGGDQGELHY
ASELVRFIREYSAGWFQIEVAAYPEVHPQAHSTDADLDHFVAKIEAGADSAITQYFFNAD
AYFNFVERVRARGVTVPIVPGIMPITNHSQLVRFSEMCGAEVPRWIRRRLGEFGDDRASI
KAFGVEVIARMCQNLLDQGAPGLHFYTLNSAESIMAISKLLAR
>A0A542KFD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SLBN-31|TrEMBL
MLATGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSVTYGAGGSTRAGTVRETQQ
IVVDTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWVPHPQGL
TYAAELVQLIKESGDFCVGVAAFPEMHPRSADWDTDVTRFVDKCRAGADYAITQMFFQPE
SYLRLRDRVASAGCETPVIPEVMPVTSVKMLQRLPQLSNAHIPSALKERILTAKDDPAAV
RSIGIEFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLGLHHPPQA
>A0A3D2SF52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides graminisolvens|TrEMBL
MKIIDLINSNEKTAFSFEILPPLKGTGIEKLYTTIDTLKEFDPKYINITTHRSEYIYKDL
GEGLYKRDRQRRRPGTVAVAAAIQNKYNIKTVPHILCSGFTREETEYVLIDLQFLGVTDL
LVLRGDKAKHESVFTPEGDGYYHAIQLQEQINNFNKGIFVDGTSMQNMEQPFSYGVACYP
EKHEESPNIEDDIYWLKKKVEAGAEYAVTQLFYDNKKYFDFVDRARQAGITVPIIPGIKP
FKKLSQLTMIPKTFKVDLPEDLTKEILKCKNDNEAQQVGIEWCIAQCKELIEYGVPSLHF
YTISAVDSIREVAQKIY
>A0A3M0GLG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium macginleyi|TrEMBL
MSEEELMVPERLALSFEVIPPRHDADEAKIDRLLEALESYHPDYIAVTSSQRSGWLAGTT
NFIERISRTTSMRPLAHLACTAGSRTELIGWTNRLVDAGVRGLLALRGDLPEEGLPEHYP
QHADELISLIRQLERQQAARFAAGRLAVGVACYPSGHVESKNEDEDFDVLLKKQRLGADF
AITQLFFDAQDFLRFSQKARLAGVHIPLIPGIMPMTSLRRVERMGELSGLAVPERVRSAL
AAATTPEEEYETGMELTAELARDIVAGGASGLHIYTHNNPDNTHDLLTRIGVDNDQR
>A9BEZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrotoga mobilis (strain DSM 10674 / SJ95)|TrEMBL
MKIVDLIKQSNKPVLSFEIIPPNVGESIDSIFNVVDNLIEFSPKYINVTKHANEIDYVEE
NGKIMKIIQKKRPGTVGVSASIKHRYNIEVVPHLICTGFNKYQLEDILIDLNYLRIENIF
VVRGDKKRYTWKETDEYEHASQLVEQIANMNRGIYTFPTKEHNSTNFCVGVAGYPEKHFE
SPNFEKDLDYLKLKVDMGATFIITQMFFDIEYYKNFVNKVRDLGIEVPIIPGIKPLGSKK
TLYNIPKTFHVNIPKSIVEEFENAKSSQDEYIIGVRHAIKLIEQLLELGVPGVHLFTMGK
GKIVKDVLSAFKGIF
>A0A1S1HPQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Providencia stuartii|TrEMBL
MTNRLSFEINATKSSSENLTELIRMTERLKPLYYTVNTEIGQTEWQDTYNRCCELKNMTD
KPVIPHIAINNKDECELYFIIEKYLKNNFMEFFVIRGDKHHVDRDKTLNYGTELIEFIRA
NYPQVNIKSSIYPDYHKESLTPEVDTFWLKKKYQLGVSELISQVCLNKNAFSYIKKILGE
EITITPSMMPLLNFKFMASFLKSNSIDYPLWIQKHIRENNSTNHREIGLKITKFLALDYL
KNENRLHFFTLNNSKVITELFNDLSDYG
>A0A2T1C0P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Merismopedia glauca CCAP 1448/3|TrEMBL
MTQNNFRAAVEAGEFLITAEVAPPKGGDPTHMLQMAQTLKGRVHAVNITDGSRAVLRMSP
VAASVILLQHGIEPICQLACRDRNRIALQADLMGAHALGIRNILALTGDPVKAGDHPDAK
GVFDVESVRLLQLIQKLNQGVDQNLKPLSDGTLDLFPGAAVDPQCGSWSGLKQRFERKLE
AGAQFFQSQLICDFDKLDKFMLQIATGCNKPILAGIFLLKSAKNAEFINRCVPGVQIPQH
IIDRLAQAETPLAEGIEIAAEQVKMASQLCQGVHLMAVKREDLIPQILDLAGIPTLNFPK
VETKYPSR
>A0A2P8GNX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga ginsengisoli|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIESIYEHLDPLMEFKPAFINVTYHRSEHMFKKR
ADGTFEKVEIRKRPGTVAICAALMNHYNVDAVPHLICGGFSREETENALIDLNFLGVDNV
LVLRGDAPKNETFFEPEPHGHRYADELLQQVVHMNNGIYLEEDLQGGVKTKFCIGVAGYP
EKHFEAPNMQTDMSYLKKKVENGADYIVTQMFFDNQKFFDFVTKCREAGITVPIIPGLKP
ITSRKQLTILPRTFHVDIPADFANEILKCKTDKEVEAVGTEWLIQQSKELKAFGVPVLHY
YTLGKPNVIRKAVEAVV
>A0A316LCE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium|TrEMBL
MSIPALFQKGRVLSLEVFPPKPDAPIEVIDGTLSLLAPIKPDYISVTYGAGGSGRSRSVE
IAKKILPICDCLSHLTCVGADAQEIDNVLDSLTAAGVENIMALRGDVPKDMDRESAFVHF
KHASDLIEHIKDRGGFHVAAACYPEGHPQSDYLEQDVDMVKRKVDAGAELLVTQLFFDNV
LFYRFMELLRKRGVTVPVTAGVMPVLNAAQIVRMTLLSGTSVPPDLAKLIARYGDNKEDF
RKAGLEFAMNQVSGLMANGVQGIHLYTMNKAEEIIQIIRETGLRSH
>A0A7Y8IWP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MSFKEQLDSGKFVVITELQPPKGNNLSELFESAELLKGRVNAINVPDLQNAIMRLGSLSV
CNLLKAKGMEVIFNLSCSNRNRLALQSELLNASALGLENLLLLQGDHPSIGDHFEAQAVF
DLDVMGLLNAAKRLQEGYDLMGNDLNGKPQFCVGTYIHATVKGHVLDLEVMDMEKKIRMG
VDFFFTNSVFDLSLFEPFIKKVAHFKVPIIAGITLLKSVGMARYINKHVEGASIPDSIID
QLMKAPDKQRTSIEIAGGLIKELRSLCQGVQIIPIGWEKQVPALLDYVGF
>A0A7Y8LRI4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
PDELIERMKSVPKERQAEEGIRICVETIQRLREIPGVRGIHIMAIEWEEKVSEIVKAAGL
LPRPQTA
>A0A7Y8HD61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophaceae bacterium|TrEMBL
MKSGSRLEKLLTGGHFVVTGELGPPKGADVAVVEKKANLLKGNVDSINVTDNQTAIVRMS
SIAVSALLVRMGIEPNMQMVCRDRNRIAMQSDIFGAYALGIRNILCLSGDHQKFGNHPTA
KNVFDLDSIQLIQTVKKMRDEHKVLGGDEIEGVPKMFIGAAANPFADPFEYRVVRLGKKA
AAGVDFIQTQCIYDMEKFERFMKMARDRGLHEKVFILAGVTPLKSVGMAKYMKEKVAGME
VPDEIIERMRKAGKEKAREEGLNICVEQIQHLRQIPGVHGIHLMAIEWEDAVHGIVERAG
LLPRPEVN
>A0A7S2XA42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lotharella oceanica|TrEMBL
NDRIKRKEHFFSFEYFPPKTEQGVKNLDKRMTDMARRGPVWMDMTWGAGGRTSDLTLTLC
DKIQNEKKVDALMHLTCTNMEKKKIDDALAGCKKVGVRNILALRGDPPQGEEAWTATEGG
FTCALDLVTYIRKTHGDHFCVSCAGYPEGHPNVRKVITDKNWDPEKNEPKYWAVRKLPDG
KYEGVSPEDWKTEQNYLKKKVDAGSDFIVTQLFYDLDIFYEWVKQCRAMGITVPILPGIM
PFFKAASFGRMTGFCKTVVPQDVLDVVKKYQEFGADKAKAKEFQEWGVKYISEMCKKLLA
SGTVPSVHLYTLNNQLVPYKILDALGFPKEKAQVPIDRTISLSVNSKRTDKGWRSGLQSN
PSTEELKANGNLAPVTEAEKKLEA
>A0A7C6W223|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadaceae bacterium|TrEMBL
MNLNFDDIPDDPSLPMPILPGHVSAGRLERVLRAGAFAVTSEMDPPDSANPEEVFARARI
FDGYVDAINATDGAGAHCHMSSVAVSALLIRAGYAPIMQIACRDKNRIAIQGDILGGAAM
GVCNMLCLTGDGVQAGDHPQAKPVFDLDCMSLLEIARMLRDEHRFQSGRKITSPPRVFFG
AVENPLAVPREWRPHRLAKKVAAGAEFIQTQYCFEIPPLREFMNRVEDLGLLDKVFILIG
VGPLRSAKSALWMRSHVPGVHIPDAVIQRLAGAEDQQAEGRKLCVELIQEIREIKGVSGV
HVMAYYQQEAVAEVIERSGMLQGRVPWYPGIRTQRQPK
>A0A6S6SYX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Campylobacterales bacterium|TrEMBL
MFEKFINKLKNDKYITVEITPPKSADINSTINKIDTLDFTKYIDGFSVTDSPLAKLKYSP
IIASYKIQQALKKPVIATMNMRDKNKIALQSDLLAGNDLDVRSILALTGDPVSISDQPKP
KGVFEGTSSLLLDIINNFNNNIDLAGKPISPSLNTIYSYAVTNSYTNKPEFLTKKIAKKL
EKNLVGIISQPVFSKDEAKSLIKIFEDASEISQNHQTQLILGFFPILSLKTAIFLNDKVP
HIKVPSFWIQSLSLAKTPKEEFDIGMKLSIDLFNELKELHPKIHIMSVNKFDIVKDILIN
S
>A0A239Q912|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas sp. CC120222-04|TrEMBL
MTAISFEFYPPKTDEQRSQLDRAAAKLKDYDPQYVSCTFGAGGSTLSYTSETVRHLNQHH
GFDAAPHLSCVGGTRQEIRELLKLYRAIGCRRLVALRGDLPSGMGFPGDMRYAAELIDFI
RAEHGDAFHIEVGAYPETHPQASDALADLKHFKAKIDAGADAAITQYFFNPDAYFHFVDE
VRRLGVQVPITPGIMPIANFSQLRRFSEQCGAEIPRWISRKMQAYGDDAESVRAFGTEVV
ARLCQRLIEGGAPGLHFYTLNLARPTTSVLKLLQG
>A0A430HE05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia atriviolacea|TrEMBL
MATPDFSIEFFPPKTPEGADKLRVARAKLALLQPKYFSVTFGAGGSTQQGTLDTVVEILG
EGHEAAPHLSCVGASRASIRAILKQFQSHGIKRLVALRGDLPSGYGGAGELRYASELVEF
IRAETGDWFHIEVAAYPEVHPQARSPQDDLQNFARKVQAGANAAITQYFYNADAYFAFMD
QTRKLGIDIPVVAGIMPITNYTQLLRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTQLCERLLAGGAPGLHFYSMNQAVPTTALWERLKAG
>A0A2E3TRU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ilumatobacter sp|TrEMBL
MARISDKLAAGRTLSFEFFPPKAAGAQLTLGRTITELAPLEPDFVSITYGAGGSDRHRTG
DVVEWISRETDVAPMAHLTCVGHTRTDVAGLLVGYRRVGVENILALGGDLPIDGSAPAGD
YSYALDLIHDVAATGCFSIGVAAHPEVHPRSASRQADRRHLAEKLRLADFAITQFFFDPE
HYVRLVDELAALGVYKPIVPGIMPVTSLGQITRMVEMSGTEVPGWFIDRLSGAHNAVDAK
HIGTELASELCRDLIEAGAPGLHLYTLNRSEIAKDIRVNLGSVLV
>A0A1V9G5B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Niastella vici|TrEMBL
MKVIDHIRQAKDSLISFEILPPLKGKTINSIYEHLDPLMEFKPAFINVTYHRSEHVFKKK
ADGTFEKVEVRKRPGTVGICAALMNHYRVDAVPHLICGGFNKRETEDALIDLHFIGVDNV
LVLRGDAAKNETVFEPEKGGNSYAIDLLKQVQNLNNGVYLEEDIRDGFRTNFCIGVAGYP
EKHFEAPNLQTDLAFLKAKVAAGAEYVVTQMFFDNQKYFDFVKRCRESGITIPIIPGLKP
ITSKKQLSVIPRTFHVDIPDDLSNEIMNCKTDADVEKVGTEWLLLQSKELKKAGVPVLHY
YTLGKPKVIYNAVKEIL
>R5HRD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:114|TrEMBL
MKLKDVWKKKEVTLSFEAFPPKKDSDFASVASAVEKIAQLKPDFMSVTYGAGGGTSAYTG
KIAQIVQAQGVTALAHLTCVSSDRDRIHHELDALRQAGIENILALRGDYPEGYDPSAPRD
YRYARDLVEEIRAYGGFSIGGACYPEGHVECPSQKEDLRHLKEKVDCGVDFLVTQMFFDN
SALYSFLYRAQQVGITVPVLAGIMPVTNAAQMTRILSLSGTTLPNRFRMILDKFRERPDA
MKQAGIVYAAEQMVDLVANGVRGVHVYTMNKPDVAAGIAENLSKVLGRT
>A0A497VDV8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. 106|TrEMBL
MNAAKTEATGFPVSLEFFPPKTPEGAEKLRAVRQRLYALHPEFCSVTYGAGGSTQEGTFT
TVREILAEGVSAASHFSCIGATRQSVREQLAVLKGMGVRRLVALRGDLPSGYGAGGEFQY
ASDLVTFIREETGRDFHIEVAAYPEVHPQARSPEADLKAYVAKVQAGADAAITQYFYNSD
AYFRFLEDTQKLGANIPVVPGIMPISSSTQLMRFSDACGAEIPRWIRLRLQGFGDDTASI
KAFGLDVVTDLCDQLRSAGVPALHFYTMNQSAATLEICRRLEL
>K8CHK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cronobacter sakazakii 701|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDRWPDELRTIARDYWNNGIRHIVALRGD
LPAGSGKPEMYASDLVALLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFA
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPALELKT
A
>A0A436W805|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M4A.F.Ca.ET.020.02.1.1|TrEMBL
QVDAVVREFADMGVTRFVALRGDPAAGVGTAYRPHPDGYANGAELVGAMKSAGDFDISVS
AYPEKHPESPDFATDFDMLKRKADNGATRAITQFFFDNDLYERYVERARRAGIYIPIVPG
ILPVHNFTQVANFSARCGALVPAWLAERFEGLQNDPQTHALVASAVAAEQVLDLVERGVS
DFHFYTMNRADLVFAICHMIGIRSHEAEAAGSAAA
>A0A8E4FDM8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter terrae|TrEMBL
MTKRIPISFEFFPTKTDVGAEKLRVVHKELQLLNPEFFSVTYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFIIEVAAYPEMHPQAESFDQDIQHFIEKANAGANAALTQFFFNPDAYFYFV
DRIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNTTDPTRQLVIDLGLA
>A0A8I2Z9T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verticillium longisporum|TrEMBL
MDKITDKIAALPANANYFSLEFFPPKTAMGFSNLRDRLDRMERALRPLFVNVTWGAGGST
AFKSLELAEICQRELGLTTCLHLTCTNMSRRLVDKALDDAKVLGIRNILALRGDPPRKAE
YQDAVDEESDDGEDFVWATDLVKYIRKNHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVEKTQAGADFIMTQLFFDIDAYDHFEQVLREHPSGAFKTIPIIPGLMPIQSYQMIKRT
TKLSHAKIPDALMARLDAVKGDDEKVKEVGVDIVSELVDQIRAVKSKRTTGPQGFHFYTL
NLEKAVSFILERTNLIPDKEQEDEEAVIDDATTPPVVPTVQINGLHPGSHHRPGRRQSSI
GSDPHNRVIVSSASNHAYETNPEGAGLPAEPINTRANTLAISEGEGVLGREATWDDFPNG
RWGDARSPAYGEIDGYGVSLHMSVTQAVRLWGHPKSSEDISTLFIKHIRGELSAIPWSEE
GLSPETNIIQEQLIELNTRGWWTVASQPAVNGVPSRDATFGWGPSHGFVFQKAFVELFLP
AADWKVLSERLTGPEVEGTVCFYACNGNGDFATSDDSGGLVRTAVPASTNAVTWGVFPGK
EIITPTIIEEVSFRAWSEEAFKIWGEWSRVYGRGHESEKFLKTVKDEYWLVNIIHHDFVE
TNALWDLLRG
>A0A7X0ZC62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Listeria cossartiae subsp. cayugensis|TrEMBL
MNLRKDLSEKVLIADGAMGTLLYSYGVDRSIEELNLSHPEDIVAIHKAYIGAGADIIQTN
TYGANYIKLARYGLEDEVKRINQAAIRLAKEAARGTGTYIFGTIGGINGAVDARLPAAPL
EEIKRSFREQLYCFLLDGVDAILLETYYDLDELKTVLKILRETTDLPVVANVSMHEPGIL
QNGQKLPDALEELIALGADVVGINCRLGPYHMARALETVPLYDKAYLAVYPNASLPEVQE
GKVIYQSDTDYFAHYGEVFRQEGARIIGGCCGTTPDHIRALRKGLQSTKPIFEKEVRPIL
ELVPEEVEDAESGERLLDKVKERLTILVELDPPRTFDTAKFFEGAKALNEAGVDAITISD
NSLATPRISNMALASILKHEYGIKPLIHLTTRDHNLVGMHSHVMGFHKLELHDVLAITGD
PTKVGDFPGASSVFDLRSVELVQLIKKFNDGISYTGKSLKEKARFHVGAAFNPNVLNLEK
AVRLIERKVEYGADYIITQPIYDVNKAVLLKEALQKANIDVPLFIGVMPLLSSRNAEFLH
NEVPGIRLTDEVRERMREAEEHGHANEEGMAIARELVDAICAHFQGIYIITPFLRYDLSI
ELAKYVQNKQQVQIVSK
>A0A850WRF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fregata magnificens|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPIGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVTMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>A0A806X168|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Enterobacter] lignolyticus|TrEMBL
MSFFHANQREALNQSLAELDGQINVSFEFFPPRTSEMEQTLWASIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKIDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIVPGILPVSNFKQAKKFADMTNVRIPAWMAKMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>A0A852ST60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Herbiconiux flava|TrEMBL
MSVVTPGQRATCPKHMEYGPCGGVDFDGTCEVGEFRCVFLDTPTVRWHGAARPEPVEPQS
GAAAMRALLATRPIVVADFPARSLDRVSLADCASALAGRVDATLAGDSGRSRVQFPPSYR
AHLIQQQGVAVWTGLNCRDRNRVALEGELAGLRAVGVAGVHCVTGDHTATGDRADAQPVF
DLDSTQLAALAAADGHLVSVAEAPTSPPVGKRAARLREKVLAGADVCFVNHAGGARPVRR
FIAETREAGADPAFIPCIPMVIDKGSAGLLRTFTTLVLPEGFLDRILHAADPYREGLDAV
TELCERMLELDGVAGVNLSGGASPGAEVEFADAMGIVAERLGLSS
>A0A7G6SGN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium sp. 628|TrEMBL
MSFFRQSRRADLGTNIKVSFEFFPPKTEVMEERLWETVTRLAPLNPEFVSVTYGAGGSTR
ERTARTIKRILTETDVNAAAHLTCVDATKEEVDTVVREFAAMGVKRFVALRGDPAGGLGA
HYKPTPGGYENGADLVAGLKAFADFDISVSAYPEKHPESPDYATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVEKVRRAGIYIPILPGILPIHNFTQVTNFCSKSGTHIPSWLAERFE
GLENDPQTHALVSSAVAAEQVLDLVERGVQDFHFYTMNRADLAFAICHLIGIRPGNGTLE
PALAGAA
>A0A1S6ETZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas sp. LM2|TrEMBL
MAATAPSLAEARALLLSPLGPVARAGDNADAVRVSFEFFPPKTDKAEETLWEAVRRLEPL
NPDFVSVTYGAGGSTRERTHRTVQRMLAETTLKPAAHLTCVEASRAEVDEVIESYKAIGV
NHIVALRGDPPGSAGIGGAYQPRADGYANATELSQAIRRVGGFDITVGAYPEKHPESPSI
DHDIDVLKAKVDAGATRAISQFFFDIDAFLRFRDRIRAAGVTIPLIPGIMPVSNFAATQR
MSASCGASVPAWLATHFDGLDDDPETRKLLAASVAAETCARLQEEGFQDFHFYTLNRADL
VYAICRVLGVREQKAVA
>A0A0Q4L558|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. Leaf41|TrEMBL
MKITDHINNSKGKTLFSFELLPPIKGQSIQWIYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARAADHSFVPTKGGHCYATDLIQHIKNHNDGKFLHEDVETFKSDFCIGVAGYP
EKHFEAPNLNADFKYLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLTQLNVLPKIFHIDLPDELTDALSYAKSNAEAKEIGTDAMIKQCKELIDFGVPVLHF
YTMGKPQQTKAIAKAIF
>A0A0S8D125|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira bacterium SG8_3|TrEMBL
MNTKTPSKLEKILKAGHKAVTSECGPPRGSDGEAIAKKADMIKDYVDAINITDNQTSVTR
LCSLAACIRLKLMGQEPVLQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQQFGDNP
QGQNVFDIDSMQLIQMVRLMRDEGKFLGGDDIERPPQMFVGAAANPFADPFEIRVPRLAK
KVAAGAEFIQTQCIYNLDKFELWMKQACDRGLHEKVYILAGVTPFKSAGMAKYMKNRVPG
MDVPDEVVKRMSGVPKEKQAEEGLKICVESMQRLKEVEGVSGFHVMAIEWEEKVPEIVEQ
AGLYPRPEVD
>A0A1V4S7U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4484_190.3|TrEMBL
ILAAGHLAVTSECGPPRGSDGEAIAKKAEMIKNHVDAINITDNQTSVTRLCSLAACIRLK
LMGLEAVLQMVVRDRNRIALQSDILGAASFDINNILCLSGDHQVFGDNSRGQNVFDIDSM
QLIQTVRYMRDEGKFLGGDEIKRPPRMFVGAAANPFADPFDIRVPRLAKKIAAGAEFIQT
QCIYNLDKFELWLKQAGDRGLLDKVAVLAGLTPLKSAGMAKYMKNRVPGMDVPDDVVKRI
SGVPKEKQADEGIKICIESIQRLKEVEGVKGFHIMAIEWEEKVPEIVEQGGLYPRPEVEE
>A0A1V4S7S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacteraceae bacterium 4484_190.3|TrEMBL
MKIRGMLLKNKFTLSFEVFPPAREGKLDSLYSVIEELVELNPHFISVTFGAGGSTRDMTV
EIASKIKNHTNTEVLAHLTCVQTTKDDTARILDDFKKENIENILALRGDPPQGENIFVKI
EGGFGYANELVEFIKAYGDFSIGVAGYPECHIEAPSLDVDIRNLKRKVDAGSDFVITQLF
FNNDDFYRFRDKAVSRKIAVPIIPGIFPIFNYAQISKIASLCGAKIPSRLHDKIYKVSEK
SEEVEKYGIEYAIRQSEELLDNDVWGLHFYSMNKSRHIMQIVRELHLSKGI
>A0A1C2K4C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. K35|TrEMBL
MTALNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLTNFVRKARAGADSAITQYFFNADCY
FYFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQA
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A1H6I1E7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus flavefaciens|TrEMBL
MKTAELFEQKTVFSLEVFPPKPDADESVIYQTLEELSDIQPDFISVTYGAGGGKNGCKTI
QIASDIQNRYGVESVAHLPCINLKKEQAVEILDNMQKCGIENILALRGDRTDDAAPAGDF
EHASDLIKFIKENYDFNIIAACYPEVHPESTGAVDDLKWLRYKVDCGADHLISQLFLDNH
SFFDFREKACIAGINAPIEAGIMPVTNKRQIERMVKLCGVELPKKFVRVLEKYEHNETAL
RDAGIAYAIDQITELIAEGVDGIHLYTMNNPYIAHKIFDAVQSLISVGSLSR
>A0A101HNE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrotoga mobilis|TrEMBL
MKIVDLIKQSNKPVLSFEIIPPNVGESIDSIFNVVDNLIEFSPKYINVTKHANEIEYVEE
NGEIIKIIKKKRPGTVGVSASIKHRYDIEVVPHLICTGFNKYQIEDILIDLNYLRIENIF
VVRGDKKRYTWKETDEYEHATQLVEQVTNMNKGIYTCPTKEHNPTNFCIGVAGYPEKHFE
SPNLEKDLDYLKLKVDIGAEFIITQMFFDIEYYKNFVNKVRELGIEVPIIPGIKPLGSKK
TLYNIPKTFHVNIPKTIVEEFEDAKSFQDEYIIGVRHGIKLIEQLLELRVPGIHLFTMGK
GKIVKDILSAFKGIF
>A0A5B6UBJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium australe|TrEMBL
MKVIDKIQSLSQDQGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGST
ADLTLDIANKMQNMICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQD
KFVQVEGGFSCALDLVKHIRAKYGDFFGVTVAGYPEAHPDAIGSNGVATPEAYQSDLAYL
KKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKT
KIPDEVTAALEPIKDNDEAVKSYGIHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMN
LGLIEESKISRSLPWRRPANVFRVKEDVRPIFWANRPKSYLSRTIGWDQYPQGRWGDSRN
PSYGALSDYQKFKNHCLGKLRSSPWSELDGLQPETKIIHEQLGKINLKGFLTINSQPAVN
GERSGSPSVGWGGPGGYVYQKAYLEFFCSLDKLDALVKKCNSFSSLTYVAVNKKGNLLSN
IGLTDVNAVTWGVFPAKEIIQPTVVDPASFVVWKDEAFEIWSRSWSALYPDGDPSKNLLE
EIQSSYYLVSLVDNNYMDGNIFGVFEDL
>A0A6B3UI05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caulobacter sp. 17J65-9|TrEMBL
MSLAAARALLLSPLGPVARAGGREHGQVKVSFEFFPPKTDEAEANLWNSIRRLEPLGPSF
VSVTYGAGGSTRERTHRTVRRILDETCLQPAAHLTCVEASKGEVDDVARAYWDAGVRHIV
SLRGDPPGGTGVGGVYAPPADGYANATELTAALARIAPFEISVGVYPEKHPESPSIDHDL
DVLKAKIDAGATRAISQFFFDIDAFLRFVDRARAAGITIPIVPGIMPVTNFRGLCRMSES
CQASVPQWLANLFDGLDDDPDTRRLLASSVAAEMCARLEEEGFSEFHFYTLNRADLVYAI
CRVLGVREGVHA
>F4GUC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pusillimonas sp. (strain T7-7)|TrEMBL
MSGKQQAVSLEFFPPRDIAAQEKLVRSAKQLLALHPAYVSVTFGAGGSTRTGTVDTVRLM
QNLGCDAAPHLSCIGASRAELADILTMYREQGIKRIVALRGDLPSGMGGDGGDLHYASDL
VSFIREHSGDWFHIEVAAYPEMHPQASSAQADLDHFVNKVQAGANSAITQYFFNADAYYD
FVDRAQARGVGVPIVPGIMPITNYTQLSRFSNMCGAEIPRWIRLRLADFGDDKASIKDFG
VEVISRLSQDLLDNGAPGLHFYTLNNAEVTMAVWKRLDLAV
>A0A5N5WL56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus leporis|TrEMBL
MHIKDKLAQNEAAGRVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKAGCTNILALRGDPPREKEK
WEAADGGFRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGSTF
IVTQMFYDTDRFIQWVNKCRVKGINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLEAL
EPVKNDDAAVKEIGKGLIAGMCRRLMAAGIKHLHFYTMNLAQATQLVLDELNLMPSEETP
LQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIRDLSDIFVRYLEGRLNRLPWSDTPISSEANTIKPNLIE
LNNRGFLTINSQPAVNGAKSSHPVYGWGPKNGFVYQKAYLELLVPPYLLDDLIARVESNE
DLTYHAVSKSGELRTNTRDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHDATSPSRKLIQGLVDTWYLVNIVNNDFHNTYNLFELFKGLNVKDLDVELTADSKPQE
NGSTDGILSETTKN
>A8H003|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)|TrEMBL
MGFHHAQHATSLNQSLSELNGDINVSFEFFPPSTPEMEKLLWNSIRRLEPLNPKFVSVTY
GANSGVRDRTHGVIERIQTETDLLAAPHLTLVDASDEELKELAKHYWNSGIRDIVALRGD
LPDGSPKPTRFANDLVRLLRSVADFDISVAAYPEVHPDASNAQSDLINLKKKIDAGANRA
ITQFFFDVESYLRFRDRCAAAGIDAEIIPGILPVTNFNQTKRFAAMTNVSIPSWLHRQFE
GLEDDAITRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGK
>A0A069D5H6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides graminisolvens DSM 19988 = JCM 15093|TrEMBL
MSQDTVDYKNHIEKMKIIDLINSNEKTAFSFEILPPLKGTGIEKLYTTIDTLKEFDPKYI
NITTHRSEYIYKDLGEGLYKRDRQRRRPGTVAVAAAIQNKYNIKTVPHILCSGFTREETE
YVLIDLQFLGVTDLLVLRGDKAKHESVFTPEGDGYYHAIQLQEQINNFNKGIFVDGTSMQ
NMEQPFSYGVACYPEKHEESPNIEDDIYWLKKKVEAGAEYAVTQLFYDNKKYFDFVDRAR
QAGITVPIIPGIKPFKKLSQLTMIPKTFKVDLPEDLTKEILKCKNDNEAQQVGIEWCIAQ
CKELIEYGVPSLHFYTISAVDSIREVAQKIY
>A0A1F9ZBP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon RBG_16_68_13|TrEMBL
MALRTEPKELAVGSRLERVLASGTFAVTAEIAPPASADPAAVRRTASLFRAVADACNVTD
CLRAHVKMSALAASAIAIQEGVEPIMQMVLRDRNRIAIQADLLGAHALGVRNVLCLNGDA
PRTGNEKDAAGVFDLTTRDMIETFRRLREQGVLRGGDRVEVAPRVLIGAAADPFGGSPEE
SFANLRGKVSAGADFIQTQAIYDVEAFEEWMGLVRKEWLHERVKILAGVIPLRSAKAARF
MAEKVPGIRIPEDILERMESAPDPRAEGLSIALRTIKALRKIDGVHGVHIMAVNWEEAVP
LLVKEAGLLPRPVSPK
>A0A0P7KLE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysinibacillus sp. ZYM-1|TrEMBL
MGLLERLQTHVLTADGAIGTVLYGYGLEYCHEEMNVQRPELIEKIHREYIAAGADIIQTN
TYGANAIKLARYGLESSVKQFNEAAITIAKRAAADGGQFVLGTIGGIRGIRKSDATLDEI
LATVEEQANVLLAGNPDGLLLETYYDFEELTATLKMLRAKTNIPIIAQVSMHEPGVLQNG
MPLNNALHELETLGADIVGVNCRLGPYHTIQAFEGVELPEKAFMSAYPNASLLDLEDGRV
VYESEADYFGRAAVELRDQGVRLIGGCCGTTPKHIAAAKKYLEELSPVSEKHAKPAKIEI
VRDAEPPKYEPLHEKVKRERSVIVELDTPRHLEIDGFLEGAKQLYEAGADVVMMADNSLA
SPRISNMAMGSLLKSTNGVRPLTHITCRDRNLIGLQSHLMGLNALGIHDVLAVTGDPTKV
GDFPGATSVYDVSSMELIQLIKQLNEGVSFSGKPLRKKANFSVAAAFNPNVRVLDRAVAR
LEKKIEHGADYFISQPVYTKEKIVEIYEATKHLQAPIYIGIMPVTSYKSAEFLHHEVPGI
KLSEDALARMKACGEDKEHATLEGIAIAKELVEVATQYFNGIYLITPFLRYDVTLELMKY
IEQLDEQKKGVSING
>A0A7L4XYJ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. QHH-9511|TrEMBL
MALGTASTRSDRARTVRDILASGKPSYSFEFFAPRTEKGERSLWNALRRVEAVGPSFVSV
TYGAGGSTRGGTVKATQKIAGDTTLTPVAHLTAVDHSVAELRNVLGQYADAGIRNMLALR
GDPPGDPLGEWIEHPEGVRYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWATDIRHFVD
KCRAGADYAITQMFFDPENYLRMRDSVVKAGCETPIIPEVMPVVNVKTLDRLPQLSNALF
PADVKERILAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLG
LHVQS
>A0A849I4Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterovirga sp. DB1703|TrEMBL
MSALAFRPSRHSTRPVKVSFEFFPPKTAEMEASLWSAIERLAPLRPSFVSVTYGAGGSTR
ERTHNTLARLVTETSLRPAAHLTCVAATKDEVDDVVRSYWAAGVRHIVALRGDPVSGPGT
RYQVHPGGYEQTCDLVAGIRRIGDFEVSVSAYPEKHPEAASLEADIDALKAKVDCGATRA
ITQFFFDNDLYLRYLDRVRARGIDIPIVPGILPVQNFKQAANFAARTGASVPDWLAARFE
GLENDVETRKLIAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVFAICHLLGLRAQAAPEP
ARAAA
>A0A3B9FEP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
EFAMAKRNGVEDILSVVVATDICADLMDNGIDQFHFYTLNRPYLTRDVCLALGIVPDTKL
ALVA
>A0A379X2T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica I|TrEMBL
MDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIP
SWMSLMFEGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGV
RPGL
>A0A059XZA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospirillum ferriphilum YSK|TrEMBL
MTFREALNAREFLVTAECSPPKGTRIDGLLDRLTPLKNRIHGINVTDNQTGVMRMCPMAM
GLHLKGIGLDPIIQITLRDRNRLAIQSDLLGMSSLGLSQVLCLTGDPPKLGDHPEAKPVF
DIPTQELIRAITLLNGGTDLSGKDLNGKTDILPGAACSPEGDQETEFRKFEEKFDAGARF
FQTQAVFSPEKMEEFMRFASPFSVPVIAGIILLKSAKMARYLNDHVPGITVPPPLIERLD
KCPPGQALESGIAIAAETIRAIRPLVHGVHIMTVGAEETIPRILDQAFG
>A0A3C1KFR7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microbacterium ginsengisoli|TrEMBL
MTSSVDSVPAPAPFSFELYPPRTAASEAALHETIARLAEVGPRFISVTYGAGGSTGGRSL
EVLRHIRATTDVEPLAHLTCVGNTYAGANRLIREFLDAGIRSFLALRGDPPAGTSEDDVY
LGDLESAAQLVQLIDRVQAERAPYQESGIPGMPGAARVDPRPRVDIAVAAFPNGHPRSRH
PREHIDALLAKQAAGATLAITQLFFHADDYVWFVDRARAAGVTIPILPGIMPITGPARLR
RVLQLTGEEIPADLAIALEVEPTAEGQREIGIAHAARLAEEVLAGGAPGVHLYAFNNHDT
VLSVLREAGILTAGASGPASTPVKESRR
>A0A537S4P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSDKSLAAAAPQRGLLSADPVGDFDGAAPRVSFEFFPPKTPEMEARLWEVIKRLESLAPR
FVSVTYGAGGSTRERTHATVRRIRNETALEPAAHLTCVAASCEEIDRVARDYWEAGIRHI
VALRGDPPGGLGSDYAPHPGGYAYAADLVAGLKRVADFEISVAAYPETHPAARSSDHDLD
NLKAKLDAGASRAITQFFFDVDLYLRFRDRAHDAGIRVPIVPGILPVTNFAQLKRMSAGC
GASIPGWMAAHFDGLDDDPDTRRLVAASLAAEQCRRLHANGVHEFHFYTLNRADLIVAIC
HLLGVRAPRAAAATA
>A0A5N3V4Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muntiacus muntjak|TrEMBL
MDRPKPKVFPAGHCCPSLGMRASEAGSRRFSVPPSISIPHLTLPRWGSAACPVVSCPLPS
PSPPPPCSRNSAMVNEPRGNGGPGPRLEGSSSGSESSKDSSRCSTPGLDPERCERLREKM
KRRMDSGDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSS
MVIASTAVNYCGLETILHMTCCHQSREEITGHLHKAKQLGLKNILALRGDPIGDQWEEEE
GGFNYATDLVKHIRNEFGDYFDVCVAGYPKGHPEAESFEADLKHLKEKVAAGADFIITQL
FFEADTFFHFLKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKD
NDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPW
ALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLK
SKSPKEELLKMWGAELTSEESVFQVFAHYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKE
ELLRVNRRGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVL
KKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFA
LWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQD
ERKTEAP
>A0A3C0TRJ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
IRRIGDFEISVAAYPEGHVDSPDMAADLDNLKRKIDAGASRAITQFFFDTDRFLRFRDLA
ANAGISVPVIPGIMPVTNFNGAKRMAVMNGASIPEWFENLFDGLEDETEIRKLVSTVAAA
EQCARLRAHGVEDFHFYTLNRAELTYALCHILGLRTAAPKGEKTI
>A0A356U523|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MNISFELFPPATSNGIGKVVEIARQLADFQPDMISVTYGAGGSGRERSSRLVAELNKPGF
PAITAHITLSGQSKQDVLQQMDEWQEHGVKRFVALRGDMPDMARPFKPHGDGFSSSLDLM
AHLASHGAEEIYGGAYPEGHPESPSQSAELDHLKAKQDAGATALITQYFFEVDCFLRFRD
RAESHGITLPIIPGILPVANFEKAKGFSKRCGASIPQFVHDRFAGLHNNPHESALMGASL
TAELVMELADEGVEHFHFYTLNRADLSLTACRMLGVRPT
>A0A1C4I913|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DvalAA-19|TrEMBL
MLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSVTYGAGGSTRAGTVRATQQ
IAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWIEHPQGV
KYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVDKCRAGADYAITQMFFRPE
DYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATVPEPLKERILAVKDDPAAV
RSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLGLHRQS
>A0A3M0XUT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
PSGRAIVPPPRFFIGAADTPIDPPTDWRPEVLRTKIESGARFVQTQFCFDAAMVARYLAR
LTEAGIAVGREVFFLIGVGPLASARSARWMNAHLPGVTVPDAIIERLARALDPAAEGRRL
CAELIDALRTVPGVAGVHIMAPKGGAEAIARVIDAAGPTS
>A0A3B9DK68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium|TrEMBL
MSVTVEAIAKAGANWSIEVTPTGATKIDSFAAVLAENTSVNVTFLPGTDPNETIAVAKRL
SDEGMNAIPHIAARSLSDKDQLDGLLKRMTSEANVSEVLVIGGGVDKPVGAFDNTMQVLN
TGLIQKHGISRIGVSGHPEGSPDIHDDALAQAIADKNAFAASEGLSLYMETQFCFDAAAV
LAWERAIREAGNALPIRVGIPGPATIKTLFRFAQISGIGPSMRFIAKQARNVAKLMTVQS
PHLLLAGLADGMASGASDADKCLIQHFHYYPFGGFAKTAAYADAIAKGQIILTKDGGFDV
QDS
>A0A1C5VMI2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Coprococcus sp|TrEMBL
MKIRDIIGQEKATLSFEVFPPKKDTDFASVEAAALGIAALRPSYMSVTYGAGGSTKGHTI
KLANEIQEKYGVPTIAHLTCVCANKDSIRTALSEMKNAGIENILALRGDIPKNYDGQVFT
DFAHASELVKLIKESGDFCVGGACYPEVHPDSANKQDDIANLKKKVEAGCEYLTTQMFFD
NNIFFNFMYRIREAGIAVPVIPGIMPITKRVQVKNAVKLSGCNVPERFKNIVDRFGDTEA
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPEVAAGIQANLSDILLV
>A0A1Y2DFW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomassariella vexata|TrEMBL
MHINEMLADAERTGQPSFSFEYFPPKTAQGVQNLYDRMERMYDFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYFGLETCMHLTCTDMGEDKVNDALQKAYKAGCTNILALRGDPPREKEK
WVATDGGFQYARDLVQHIRKKYGNHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGATF
IVTQMFYDVENFVRWVRKVRERGITIPIVPGIMPIATYASFMRRAHHMKCNIPEYFMAAL
EPVKNDDAAVREVGKALVADMCRKILAAGIVHLHFYTMNLAQATRMVLEELDWMPTTTRP
RKHTLPWKQSLGLRRREEDVRPIFWRNRGKSYVMRTQEWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNESNRKKWGEPKSIKDVAHLFVRYLEQEIDSLPWSESPITSEAASIKQDLID
LNRRGLLTINSQPAVNGVKSTHPVHGWGPPNGYVYQKSYLELLVSPELFEKILPRIQNHP
DLSYYAVTKSGSLISNVSNEGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGLDW
AHCHDANTPSRVLIDKMMSDWYLINIVNNNFHEPRTIFQLFNGLVVEGLDDPAVVESATA
PEPQINGVHKETTA
>A0A534IEC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MAGSRPLRVGSHLEKVLAAGTFAVTAEVTPDASASPNRTRAQARALRGHVDAVNVTDSPR
AMVKISSLAASAILLQEGVEPVMQMVTRDRNRIALQADILGAHALGVRNIVAMSGDDPRL
GNEPDAVPVYEWTTEQFLAAAKQLRDHGKLAGGEVIDDPPNLFLGATVNPFGAPAEETVV
NLRGKVDAGADFVQTQAVFDIEAFEEWMRLVRKEWLHEKTHIVAGVIPLRSAKMAKFLDD
KVPGIDIPSAVFERLGAANEVKTEGLHLAVETVDRLRGVEGVRGVHIMAVEWDDAVPKIV
SAAGLHPRPS
>A0A853XBE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. L27|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A6L9K6V5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paludibacter sp|TrEMBL
MSVVEKIKSAKSTAFSFELLPPLKGNGIEMVHRTIDALLEFDPKYINITTHRSELAFKEN
AQGLFEQVAERHRPGTVAIAAAIQNKYKISVVPHVICSGFTREETEYALIDLQFLGITDL
LLLRGDKARHERDFSPTGHRFATELQGQVNNFNKGLFLDETKMKSPIVPFSYGMACYPEK
HEEAPNMESDLFYAKQKVDAGAEYLVTQMFFDNQKYYDFVEKCRAQGINVPIIPGIKPIT
LKNQLTVLPKIFRSEIPEEFATELKKCNSDAEAVEVGVEWCTKQAKDLITYGVPSIHFYS
MMATQSVKRVAKEVF
>A0A2Z4LU20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Muricauda aurantiaca|TrEMBL
MKVTDHIKKAKGETLFSFEIIPPVKGKSIKELYDNIDPLMEFNPPFIDVTTSREEFVYIE
KGNLLDKKLTRMRPGTLGICASIKHKYNVDAIPHVLCGGFTKEETEYLLVDCHYLGIDNV
MALRGDAMKEEKYFEPTNGGHQYASQLVKQIQELNCGNYLHEVIETDNCSDFCIGVAGYP
EKHMEAPSLKSDLKRLKEKVDRGADYVVTQMFFDNQKYFEFLEEARKMGIDVPIIPGIKP
IAVKKHLQLLPQVFRVDIPEDLIEAVEKCKTNKEVRQVGVEWCIHQSKELKEAGVSVLHY
YSMGKSDNIKAIAKEVF
>A0A534K5R3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
RDRNRIGIQGDLLGASALGIRNVLCLWGDPPTAGNEKDAKPVYDLTTEEMIATFRVLRDT
GTLRGGDAVEVPPKVFIGAAADPFRGSKEESFAKLRAKVTAGADFVQTQGVYDVDRFEDW
MRLVRKEWLHEKVYILAGVIPLKSPKMARFMAEKLGAVIPKQIMDRMEKAPNPRAEGLSI
AVRTIKALKRIDGVSGVHIMPVGWEGIVTELVKEAGLLPRPEPAAALV
>A0A7J2NKH8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Euryarchaeota archaeon|TrEMBL
MSEQSNLEKILSSGKFAVTAEIGPPRGADPTEMIELARKIKGSADAFNLTDNQTAIVRLS
SIGSAVLLMKEGIEPVIQMTCRDRNRIALQSDLLGASAIGVKNVLCLTGDHHTFGNEKSA
KGVFDLDSISLLNTFKNMRDTKKQLSGEELDSAPNIYLGAAENPFATPYEYRAIRMAKKV
KAGAQFIQTQAIFDLDWFERWMAEVRKMDLHEKVHILGGVIPVKSAGALRYMKNKVPGMI
VPDALIGRMNRAEDKKEEGIQICIEMIERLKQIEGVHGVHIMAVMWEQIVPRLVTDSKLM
PRTSV
>A0A8E7QKC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Corvallis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>M2SQZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cochliobolus sativus (strain ND90Pr / ATCC 201652)|TrEMBL
MHISQKLAQAKREGKPTFSFEFFPPKTAQGVQNLYDRMDRMHSFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALREAYQAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDDVDELIDHLKEKVDAGGSF
IVTQMFYDTDLFLEWVRKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTKCHIPDDWTKAL
EPVKNDDVEVREVGKTLVADMCRRLIDAGITHLHFYTMNLAQATRMVLEELELLPDVESP
LEKPLPWRPSLALNRREENVRPIFWRNRQRSYIARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPLTIRDLSNLFVRYMEGKVESLPWSEQPITAEASSIRDDLID
LNRRGFLTINSQPAVNGVKSSDPVFGWGPRNGYVYQKSYLEVFVSPEHIAEIITRLERDP
EFTYYAVNKNGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDVIDTWYLLNIVHNDFHATRGIFPIFNGLEVKDMDKPLHTPSADL
PNANGSETVNGAKGVNGTNGTHKEESPSLIDVAKAAAIEVTNGMKSLAVSN
>A0A091HRH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calypte anna|TrEMBL
MVNETQPTCCASPSSKSDGGSSSGSEGSKESSRCSTPVLDGDRHERLRDKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKEDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVGGFNYAVDL
VKHIRSEFDDYFDICVAGYPTGHPEAESYEADLRHLKQKVFAGADFIITQLFFRSETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGVVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIYDNYYLVNLVDNDFPLENCLWQVLDDTFELLN
>A0A0A1HTT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SHC52|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTMNTVLQLE
SEVKIPAAPHLSCVGDSKDDLRTLLTRYKAAGIQRIVALRGDLPSGMGMASGELRHANDL
VSFIREETGEHFHIEVAAYPEMHPQARNFEDDLRNFVNKANAGANSAITQYFFNADSYFY
FVERVRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTSSIQRFG
EDVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A4Y9J8B1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus cuniculi|TrEMBL
MAHTPSLSFEVFPPNPATGNEKILSALRDMQDLAPHFISVTASNNKFNIEETTVRLADYI
HNDLGVPSIAHLPAIYLTKEQVANILSALDQIGVTTILALRGDIIPDVAPQNDFQYATDL
ISFIKDQAPHFDIIGACYPEKHPDSPNQVSDIKHLKKKVDAGCSSLVTQLFFDNDVFYDF
QEKCQLADIDVPILAGIMPIINRNQALRLLRACENIRLPRKFRAILDKYEHDPESLRAAG
LAYAVDQIVDLVTQDVAGIHLYTMNNPQVANHIHRATYSLFKHSAV
>A0A2N6IDL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp. ROICE36|TrEMBL
MEKHNFSIEFFPPKTPEGAEKLRATRIKLSELQPKYFSVTFGAGGTTQQGTLDTVREILA
AGEQAAPHLSCVGGSRASIRAVLADFKAAGVSRIVALRGDLPSGYGASGEFRYASELVEF
IRAETGDHFHIEVAAYPEVHPQARSPQDDLQAFARKVQAGADAAITQYFYNADAYFQFVE
QTQKMGINVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTGLCERLLEGGAPGLHFYSMNQAAPTTALWQRLVK
>A0A1I3ETU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas guineae|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMNVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKIPAAPHLSCVGDSKADLRDLLGLYKGAGIKRIVALRGDLPSGMGMASGELRYANEL
VEFIRAETGDHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTSSIQAYG
EQVISEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>L1NQV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. oral taxon 332 str. F0381|TrEMBL
MKITEHIQKAKGKTLFSFEVVPPKKGNSIEELYKNIDPLMEFQPPFIDVTTSREEYYYIE
HPNGLLEKKLTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCFYLGIDN
VMALRGDAMKEQRYFQPTSGGHTYASDLVTQIHNLNKGVYLNGIAADQKADFCIGVAGYP
EKHLEAPSLASDLQRLKEKIECGADYVVTQMFFDNQKYFEFVDKAREMGINVPIIPGIKP
IAIKKHLNLLSQAFKIDFPEALIKAVEACKNNNEVKQVGIEWAVQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A5B0DD57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus cristatus|TrEMBL
MVNRQTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLAE
FISNDLEIPTIAHLPAVYLTKEMVSNILQALDRVGVNQILALRGDIFPDVAPKDDFKYAT
DLIEYIKTEAPHFDIIGACYPEGHPDSPNQITDIQNLKKKVDAGCSSLVTQLFFDNERFY
DFQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRA
AGLAYAVDQIVDLVTHDVAGIHLYTMNNAATAYHIYKATHALFNHTPSVQSF
>A0A1W9K7F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteobacteria bacterium ST_bin14|TrEMBL
MTIPVSHIEEARRALDAPLFADLAGDANVSFEFFPPKTEKMEQALWETVQTLEPFGPRFV
SVTYGAGGSTRERTHATVARIQRETSLGAAAHLTCVEASRDEIDEIADAYWQAGVRHIVA
LRGDAPGAGGFVPHPQGYTNAADLVAGLKRLHPFEISVAAYPERHPDSRDQAEDLDNLKR
KLDAGATRGITQFFFEAETFFRFRDDAVAAGIDAEMVPGIMPVTNFASILKMSAMCGTAV
PPWLGRLFEGLEDHATSRQLIAATLAAELCRNLYIGGVRDLHFYTLNRAELSFAICHLLG
LRAKVAPVAVDAVA
>A0A177HY82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces jeddahensis|TrEMBL
MLATGKTTYSFEFWAPKTPKGERNLWNALRRIEAVAPSFVSVTYGAGGSTRAGTVKATEQ
IAADSTLTPVAHLTAVSHSIAELRNIIGQYADAGIRNMLAVRGDPPGDPMGDWIPHPQGL
TYAAELVRLIKESGDFCVGVAAFPEMHPRSADEDTDVQHFVDKCRAGADYAITQMFFRPE
AYLRLRDRVEAAGCTTPIIPEVMPVTSVKQLERLPQLSNAVIPDSLKERILTAKDDPAAV
RSIGIEFATEFCARLLSEGIPGLHFITLNNSTATLEIYENLGLHHPQA
>A0A1U9LA51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Polaribacter sp. BM10|TrEMBL
MKITDHIKKANGKTLFSFEIIPPKKGNNIQELYNNIDPLMEFKPPFIDVTTSREEYVYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFSKEETEYVLVDCHYLGIDN
VMALRGDAMSHQKYFEPNKDGNHYAKDLVSQIQDLNCGKYLHEVVEASNKSDFCIGVAGY
PEKHLESPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFEFVAAAKNAGINVPIIPGIK
PIAVKRHLQLLPQVFKIDLPEPLITAVEDCSNNKAVRQVGIEWAIQQSKELLAAGVPVLH
YYSMGKSDNVQAIATELF
>A0A7V4LDF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacca acetoxidans|TrEMBL
MTMTAGSNLEKILRAGHKAVTCECGPPRGADAEHFRHKASHLKGYADAVNVTDNQTAVVR
FCSLAACRILMDMGIEPVMQMVTRDMNRIALQSNVLGAAALGVKNLLCLTGDHQSFGDHP
QAKNVFDLDSTNLLHAVRQMRDEGKMLSGTEVQGRPAMFIGAAANPFADPFEFRVIRMAK
KIKAGAQFIQTQCIYDMDRFAKFMEMANDMGLTEKCYILAGITPFKSVGMANYMKKFVPG
MLVPDYYIQRLKGVPKDKQGAEGIKIAVEQIQQCLEMKGVAGIHLMAIEWEEKAPEILEA
AGLYPRPKVD
>A0A847X2M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacteriaceae bacterium|TrEMBL
MIDDNIRASRKTASERPELQISFEFFPPKTDAMEERFWDSIGKLAPLKPRFVSVTYGAGG
STRERTLRMVSRITADTGVPAAAHLTCVGATRDEVDAVVRGYKEAGVSSIVALRGDPPEG
VGQPFTPHPGGYKNAADLVAGIRKIGDFDISVAAYPEKHPQSESWDADIDNLKRKLDAGA
NRAITQLFFSNADYLRYVERARKAGITAPIVPGIQPIHSFKQISGFAARCGASIPTWLAE
RFEGLDDDPETHALVAAAVAAEQVTELLDEGVTEFHFYTLNRSNLVLALARLLGRRP
>A0A7J4CZ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marine Group III euryarchaeote|TrEMBL
MRFRDKVRKPKRPVVAYEILPPREKDGTLNSYAERISSLLSQTHIDAINIPEVHEENARG
LRPVKNLERAEAREFGRLLQDNVGIEAIVNRVTVHNDLDYQKSWIKETFYDYDIENLILV
GGESSDIKYPGPSVNETSEYITRDLNAGRFDFFCGGITIPSRKIESVRLLKKGSNGIEFF
TSQVLYDGKKIKKMLKYYDDVCKENNVLPRRILLSFAPVSSKKNIDFLKWLGVEIPSQTE
KRLTNKKTSMSDESLEIASEILKGILNNNEKLGITVPIGLNVEHIMSYNFQSSINMLQEL
SKIYREFCIKTSLYD
>A0A4Q0ZCN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter cloacae|TrEMBL
MFETLIQKLQEDKYLTLETTPQHEPSMHNIIERIKKFKLHEKVDGFSCTDNPLAKLKYNA
LFASLKLQQEFNKPVIATMSMRDRNKIALQSDLMGANDFDVRAILALTGDPAKMSDQPHA
KGVFEANSLMLLKIIKSFNYGMDFAGRPFKIEPKQIFPFAVVNSYAKNFSTLERKMNQKI
QNGAVGIISQPVFDIENAKKLLESFNIAKQDVEGDKQKAQLIFGLFPVTKLRTALFLSAQ
VPGIHVPQFWIDALENAHNISEEEEYKVGMQLSSDLFKEINRLHPKIHLMTANRFDIANE
IIS
>A0A5B1LMF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides humilatus|TrEMBL
MDLTARITAGRGDFVLFAITPPRQSTPSDRLPEIARATIERLENLALDGLVLYDIDDETS
RNPAERPFPFSPTVDPSDYRAGHLGPWRTPVIVYRAVGKYERDDLRDWIAAQDPHNTLTV
MVGAASSGASPAVTLADAQAMRSELNHDLLLGGVAIPERHSRRDNEHLRLIAKQEAGCRF
FVTQVVYDLNAAKNLVSDYRYECEARGLAPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLRHATNPLAASLEQAATTAIELVDYCRRLGVPFGLNVESVSIRREEIEASVELAAQL
AAHLRS
>A0A1F2TZI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium RIFCSPLOWO2_12_FULL_66_21|TrEMBL
MPMSPFLAEVDRRVLVCDGAMGTMLYGKGIFLNRSFDELNLTQPDLVAEVHQAYVRAGAD
VVETNTFGANRIKLGAFSLAERVHAINLQGARIARHAAREQAFVAGAIGPLGIRIEPWGK
TGVDEAEEYFAEQARALAEGGVDLFILETFRDVNEIGAAIRAVRSVCALPIVAQVTTEED
GNSLDGAAPETFVPELERLGADLVGLNCSVGPAAMLETIERMAHVATVKLSAQPNAGRPR
EIEGRNIYLCSPEYMASYARRFIANDVRLVGGCCGTTPEHIRHIKNAVRAMAPVTARTAV
TAPSAKAPEAAVAPVPRGEKSRLANCLERGHFVVTVELLPPRGFRADALVEQARQLRIRG
VDLINIPDARRASARMSALSAALLVQQQAGVETVLHYACRDRNLLGMQSDLLGAHSMGIR
NLLIITGDPPRVGDYPDATAVFDVDSIGLTNVVTRLNRGLDIAGQGIGHPTAFHVGVAIN
QGALDLEEEIRRFQYKVEAGAEFAITQPVFDARELAQFLERVAAFRIPVIAGVTPLESVR
HAEFMANELPGVHVPDATVERMRRAEAAGQAAAEGLAIAREVVSEIRPLVQGLQIATAGG
SVEAALAVIEAVAV
>A0A827Y085|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLNDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>Q84IM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sporogenes|TrEMBL
MHIKELFNQKNLVFSFEIFPPKVTSSIETIYETLEELKDLTPDFISVTYGAGGS
>A0A1G8YW84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces indicus|TrEMBL
MDRARTVREMLATGKTTYSFEFSAPKTEKGQRNLWTSLRRVEAVAPDFVSVTYGAGGSTR
AGTVTETQQIVADTTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNILAVRGDPPGDPMG
EWVKHPRGLTYAAELVRLIKESGDFCVGVAAFPAMHPRSPDWDSDVRHFVDKCRAGADYA
ITQMFFHPEEYLRLRDRVEAAGCATPIIPEIMPVTSVRMLERLPQLSNAEIPAGLKERIL
TSKDDAAAVRSIGIEFATEFCARLKAEGVPGLHFITLNNSTATLEIYENLGLHHPQA
>A0A3D2BK40|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Proteus sp|TrEMBL
MSFYHASQHEALNQNLAELNGKIDVSFEFFPPRTEEMENTLWQSLARLNTLKPRFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCVDASREELQHIAQDYWQNGIRHIVALRGD
LPDNSKKPQMYATDLVHLLKSVGDFDISVAAYPEVHPEAKSAQADLINLKKKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIIPGILPVTNFKQLTRFAGLTNVKIPGWMNKMFD
GLENDAETRSLVGASIAIDMVKILSREGVKDFHFYTLNRSELTYAICHTLGVRPELVTA
>A0A0U2X3I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli|TrEMBL
MWFRNARKKLSPTHDSATDSTDALRSSVSLLARDLSLEVSPREALRGAEGLETLAPGTRV
FITRLPKGSFEETLAASTRLRELGLRPVPHITARTTSDAATFAKQLGRYVGEAGVREILL
VAGSNEKAEGAFSNTLQILESGVIESSGLTALNVAGHPEGHPQADERELHRALEVKNAFS
TRTGIPLTIVTQFFFDPAPIIAWEARIREKGNRLPIDIGLHGVTGVASLAKHAVACGVGA
SIKVLGSHSGSVLQFAQIRTPDRLLSGLAAAKARDPANLFRNIHVFPLGGFKRTVEWANA
VRNGRYSFASDGQLEVATSD
>S7WCZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter junii CIP 107470 = MTCC 11364|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAINDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIQRFVEKVQAGANAGITQFFFNPDAYFYFI
ERLAKSGINIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVNLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>D0KXU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halothiobacillus neapolitanus (strain ATCC 23641 / c2)|TrEMBL
MHTPLSCEFFPPKSDEGALKLRAVTEQLTSALKPEYFSVTYGAGGSTQDRSFATVQAIQT
ESGVPAAPHLSCIGSTRASIAAILDQYRALGIKRIVALRGDLPSGMRDPGDFRFASELVA
FIREHSGDWFHIEVAAYPEFHPQSANARADLLHFKQKVEAGVDGAITQYFYSIEAYARFL
DDCEKLQIMIPIVPGIMPISNYTQLARFSDASGADLPRWLRKRLEAFGDDMDGLRAFGHD
VVTGLTSDLVQAGAPGLHFYTMNQAVPVINICRDAGLMPSQPN
>A0A3G6J5Q7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium gerontici|TrEMBL
MPTPAPARFQRPITDVIADTPPGIVPFSVEFMPPRDDAAEARLWNAAVDFHDLGAAFVSV
TYGAGGSSRERTLRVAKKLAQHPLTTLVHLTLVNHTTEELEQILQDYADAGLSNLLALRG
DPPGADPLGPWEATEGGLEYASDLIELSKRFSASEHFQVGIASFPEGHFRCENLEQDTEM
TLKKLRAGADFSITQMFFDVDYFLRLRDRLVEADPEHGAKPVIPGVMPITSIRSVKRQIE
LSGATLPEGLRRRLLRAEQLAAESGQDEVRKVGIEITTEMVERLIAEGVPDLHFMTMNFA
RATQEVLHNLGMAPAWGTELGHDALR
>N9B995|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter towneri DSM 14962 = CIP 107472|TrEMBL
MTKQVPISFEFFPSKTDVGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLSTISDFN
GKGTPVAPHLSCIGDDKARIAELLDIYKAQGIDRIVALRGDLPSGQVGLGELPYASDLVR
FIREHSGDHFHIEVAAYPEMHPQADHFDQDIKNFVTKVNAGANAAITQFFFNPDAYFYFV
ERIQKQGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIIKLCERLIAGGAPSLHFYTMNNTEPTRQLVTDLGLA
>A0A134BV94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Veillonella dispar|TrEMBL
MMTLREKHQQGKFTITVELDPPKSSSAQKVFDQASRLKGKVDAINIADSPMSKMRMSPIS
LSYLLQHNEGIETIFHLTCRDRNIIGLQSELLGAAALGVNNILTLTGDKPDNGDHPFAQS
VFEVDCMGLLNIAKTLNAGKDLAGNDLDEPTNFYIGATGNPGAPDLEIERQKLAAKIKNG
AHFVQTQPIYDLEQAKRYIDKMSEFDVPIMLGLIPLKSFKMATYLHEKVPGINLTQEILD
RVEKGGKEAGTEIAIETLEQIKKIAAGVHIMPLNDIDTTLHIIDHV
>A0A178C4M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fonsecaea nubica|TrEMBL
MHVSKKLELAHQQKKPTFSFEFFPPKTAQGVQNLYDRMDRMHNLGPTFIDITWGAGGRHS
QLTSEMVNATQNYYGLETCMHLTCTDMERNQVDEALRRAYKTGCTNILALRGDPPRDQEK
WEAKDGGFRYAKDLVKYIKAKYGDHFDIGVAGYPEGCDDQRDVDLLIDHLKEKVDAGASF
VITQMFYDVDIFLNWVKKCRDRGITVPILPGIMPVQTYAAFVRRANWTKCHVPPEWLEAL
EPVKNDDAAVRAIGKDLVADMCRKILDFGIQHLHFYTMNLAQATRMVLEDLSLTPETSGT
RLEKPLPWRQSLGFNRRDETVRPIFWRNRNASYISRTADWDEFPNGRWGDSRSPAFGELD
AYGIGLKGTNEANIKLWGKPRSLRDVTSLFVRFLQGDLERLPWSEGAISSEADIIKDDLL
QLNTHGFLTINSQPAVDGASSTHPIYGWGPAGGWVYQKAYLELLVFPSMFKTVMDRLNAD
KNLTYYAVNRKGELYTNTKDEGPNAVTWGIFPNREIVQPTIVETVSFLAWKDEAFRLGQD
WAKCYPAGSGSRKLIEKIMDECYLVNIVNNDFHQNKEIFKVFEGLETKDLDLVIEDTVPS
SVENGTKEVPNGDASLGDVEKGLANGEQHQAPSKASADVLSN
>A0A844YF84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania oceanensis|TrEMBL
MTEQLDPVHEARTAHDEPLFSGLPGDIAVSFEFFPPKTDKMAETLRESVAMLAPLGPRFV
SVTYGAGGSTRERTHDEVVRINNETGIPAAAHLTCVEATREEVDAVARHYWESGIRHLVA
LRGDPPDGKAGYSAHPDGYANAAELVAGLKAIAPFEISVGAYPEVHPEAADEAADLDNLK
RKIDAGATRAITQFFFEPDCFFRFRDKAAAAGIDAEIVPGIMPVMSFAAVQRMSGLCGTS
IPGWMEGLFEGLDDRPAARQLVSATISAELCRRLYAGGERNFHFYTLNRAELSYAICHML
GLRPKA
>A0A4R5SNW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLRTALHDRTFVCVMEFVPKPSAERFAAMQAIMDRRQLCGWPLTVAIGDRVASALDLS
PLDALDSFATPLPALTHFSGKNRERHDLLAQLQRMQASGQEQLLILTGDRLPGHQPGERP
VRYLESVAALQIARQAGPHLLLGAALNPFKYREEEGGAQYCKAEKKLAAGADFLTLQLGF
DAGKHHEALQWMQRQAQPKPLLACLMSLTHGRAAMLEHVAGVTVTPSMLDMLEAEAAVSK
AYAQARSVDRLALQIIGVKLMGYAGVHLSGIHALEQLVTLEARLEHWQNRLHTLEQWAPE
WAASWQMPGLPAVTFHPPEGNWRLGETRSNASLKEKARYHLLHGAHALLFSRDNWLSKTF
GWAVRQPLWATATGARVLHRLERSAKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTTLNRCEFGDRECIHSVKYRTAVAVRQTAVLTQRLIPCISAESRHQSSWPVWFDAAQL
QHSAPSSIGPMLRQDASVKAGSSNPGKKRSSEALAETG
>A0A410WIE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus vallismortis|TrEMBL
MGLLEDLQKQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEGDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEQPDGLLLETYYDLEEAREVLKIARKETALPIMLNVSMHEQGVLQDGTP
LSEALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSALEFRKQGARIIGGCCGTTPNHIQAMAEAVGGLAPITEKEVKVPAKECIS
VQHERTEPGLNEIAVEKRSIIVELDPPKKLSFDTFLSAAAELKEAGINALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDSIREKMALAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIYLH
>A0A8I1EML9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSLLKTALREQNFVCVMEFVPKPSAERFAAMEAIMARTHLCGWPMTVAIGDRVGSPLDMS
PLDALASFSNPVPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQVARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAIHWMRRQASPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMRDMLEAETAQSK
AFAQARSVDRLALQIIGTKLMGYAGVHLSGVHTLEQLLALEARIEYWQTQVQSLEQWAPA
WHASWQMPGLPAVTFHPPQAGWRLDESRVDASFKEKARYHLMHGMHALLFSRRNSLSKAF
GWAVRQPLWGTRVGAHVLHTLERSVKRPLVGCDTCGRCRLEDTLYICPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVETRHRSSWPQWFAGQAP
QRLSPQPLPRSQPES
>A0A7Y7J9N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSQERRYSFEFFPTKTDAGHEKLMGVARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKIPAAPHLSCVGDTKAELRALLAEYKAAGIKRIVALRGDLPSGMGMASGELRYASEL
VEFIRQETADHFYLEVAAYPEMHPQARNFEADLANFVHKVKAGADSAITQYFFNADSYFY
FVERAQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYADDTASIQAFG
EEVITRMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A6B3EVU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID11233|TrEMBL
GGVRNILAVRGDPPGDPLGDWVAREDGLTYAAELVRLIKESGNFCVGVAAFPEMHPRSEN
WDSDVRYFVDKCRAGADYAITQMFFDPASYLRLRDRLAAAGCETPVIPEVMPVTSVRQLE
RLSRLSTASFP
>N8XVM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter schindleri NIPH 900|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLADFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQADNFDADIKRFCEKARAGANAALTQFFFNPDAYFYFV
ERIQKEGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VIVKLCERLIAGGAPSLHFYTMNTTDPTRQLVKDLGLA
>A0A6J4XMB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius sp. associated proteobacterium Delta 1|TrEMBL
MIVADRKPVEEIIEYLKDHKNILVLGCNECVTVCEAGGKKEVQVLASALRMNAQNQGNEV
KIDEVTLERQCDQEYVEEIRDIIDQYDAVLSLACGVGVQFTAEQYPSTMIYPGVNTCFMG
ATEKRGLWTERCQGCGQCILATTGSICPVARCAKRLFNGPCGGSTAGKCEINAEVDCAWQ
LIVDRMNALDKLDQYETLCPIKDWSTDRAGGPRKVVREDVQQ
>A0A2S3W901|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas putida|TrEMBL
MSEERRYSFEFFPTKTEAGHEKLMAVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLE
HEVKVAAAPHLSCVGDSKADLRGLLSEYQAAGIKRIVALRGDLPSGMGMASGELRYASDL
VEFIRQESGDHFHLEVAAYPEMHPQAQNFEADLSNFVRKVKAGADSAITQYFFNADSYFY
FVERVQKMGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSASIQAFG
EEVISNMCEQLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A4Y8ME41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. B2|TrEMBL
MGEYLATGRASFSFEFFPPKTPDGERQLWTALRQIEALHPSFVSVTYGAGGSTREGTIRV
TERIATDTTLTPIAHLTAVNHSVAELRRVIGNYAGVGVRNVLALRGDPPGDPQGTWTAHP
AGLRHADELVRLVRSVGGFCVGVAAFPDKHPRSVDFDSDARYLVGKFDAGADYAITQFFF
GADDYFRLVDRVRRLGCDKPIIPGIMPVTNVAQIVRMAQLSGAAFPPALASRLQAVADDP
AAVRAIGVEVATELSRRLLDGGAPGLHFITLNRSSATREIYQAVR
>A0A3R9ZI24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium sp. YIM 101343|TrEMBL
MNTTAAHDSTKRRFSASAPLDTFDPAEAHQPHVPARTSLSFEVMPPRHDADEAKIEELLA
TLESYNPDYISVTSSRNSGWLEGTAEFIAKISARTRIPTLAHLACTAGNRDELIGWINRL
MDSGVRGLLALRGDYAEGQTAMLEGHLPHATDLISLIRSMENEQRARFGAGRLAIGVAAY
PSGHEESASRDEDIDVLLAKQRLGADFAITQLFFDAEDYLRFAERARLAGVRIPLIPGIM
PMTSVARLRRMGQLSGLNVPDRLIRRLETAGPEGEYQTGLDLTAELAQTILAAGAGGMHV
YTFNRPDTTTELLDRIGISPRTIA
>A0A1B8T852|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. AU12215|TrEMBL
MSQKDRRFSFEFFPAKTEAGHEKLLATARQLAAKKPDFFSCTYGAGGSTRDRTLTTVLQL
DGDVQVPTAPHLSCVGDTKAELSALLAHYKDAGIRRIVALRGDLPSGMGMASGELRFANE
LVEFIRAETGDHFHIEVAAYPEVHPQARNFEDDLANFVRKVKAGADSAITQYFFNADSYF
HFVERAEKLGVSIPVVPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDIASIQAF
GEQVITDMCERLLEGGAPGLHFYTLNQAEPSLALWNNLKLPR
>A0A3A8ELC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter guerrae|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKTVHQELQLLNPEFFSITYGAGGSTRERTLAAIHDFN
GKGTAVAPHLSCIGDDKIRIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAETFDADIKRFVEKVNAGANAGITQFFFNPDAYFYFI
ERLEKEGINIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A1H2FJZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobacula phenolica|TrEMBL
MNLKESLEKKRFVVTSEVQVPLGDEESEGLVESLGRVKGRVDGLSIAEIELEGVVSDTIK
TCGLLKENNLNAIYQTTTRDKNRFQLQKDLTLAHETGVDNLLVFTEDYRISGDTLQESMF
FHVDSGKLGSVLNHLKQGVTIEGKELESKVEFSLGSGIETPWGKSMPKRGMEEMEDMMNV
GAGYFLTTPIFDIDQFAKFMKQVEPFRVPVIAEVMILRTAGMGKFLNRHFKSGLVPEWVI
QKLMNATNKKKASMELFADTVKSLKDICQGVHIVTIGGVDNLVQYLNAAKLR
>A0A3N7DRY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. KBW01|TrEMBL
MKITDHIKNAKGKTLFSFELLPPMKGQSIQWVYDAIDPLLEFNPPFIDVTSLREDYIYKE
QENGLLQKVSYRKRPGTIAICAAIIHKYKIDAVPHLICGGFTKEETENALIDLQFLGIDN
VLALRGDARQAEASFIPTKGGHHYATDLIQHIKDHNNGKFLHEDIDTYKSDFCIGVAGYP
EKHFEAPNLNADFKYLKKKVDMGAEFIVTQMFFDNQKYFDFVKKCRENDINVPIIPGLKP
ISTLKQLTVLPKIFHLDLPNELTEALSYAKNNAEAKEIGTEAMIKQCKELMDFGAPVLHF
YTMGRPEQTKEIARAIF
>A0A3R6T105|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. AF12-19|TrEMBL
MNLREYLKTTNLITDGAFGTYFAAKYQTQDIPELANITAPEKVKKIHEEYLNAGAKFIRT
NTFASNKETLQEDFAEVEKNIQAAVEIARDAVNGRDAWIAGDIGPIPVNGTEDAAAAADE
YYQIAKTFAERGVTVLDFETFADLDGILPAIKKICAEYEMFIMVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIAAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPAYFAEKMKELQALGADILGGCCGTTPEFIREMSSWDGILNKIVLDTETDNGEQTGH
VQRHGFLYDENGERKQKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMASKVRQATGLSVMPHICCRDRNAIAMRSLFLGAAINDIHNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTEEDAARLRRIKDETGATILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKANRKEGEAAGIQLAKEVMKMVEDFADGYYFSFPFNRVYMLQDIMGK
>A0A8D6NP01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calothrix sp. PCC 7716|TrEMBL
MLIVMLDTLTPITPVKVSSFRAAARNGEFLVTAEVCPPKGGNPQHMLQMAATLKGRVHAV
NITDGSRAVLRMSPLVASAILLQNGIEPICQFACRDRNRIGLQADLMGAHALGIQNILAL
TGDPVKAGDHPDCKAVFDLEAVRLLQVIQKLNLGVDYNDKPLTDGALDLFVGAAVDPQCK
SWSGLQSRFEKKVEAGAQFFQSQLITDFERLEKFMDTIAAGCNKPILAGIFLLKSAKNAE
FINRVVPGVNIPQHIIDRLAQAKDPLEEGVKIAAEQVQIARQLCQGVHMMAVKREDLIAP
ILDMAGVVAVK
>A0A7U4SQY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. Bp5365|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVE
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESFGDDKDSIRAFGADV
VTGLCRRLVDAGVPGLHFYTLNGAAATKIVCERLGL
>A0A192D4G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Erythrobacter neustonensis|TrEMBL
MTPTLDQLNEYRTATDTPLFSGLPGDVAVSFEFFPPKSAKMEEQLWDAVTQLKPLGPSFV
SVTYGAGGSTRERTHATVARIIAEAKLPAAAHLTCVAASKDEIREVAEQYWDAGVRHIVA
LRGDAGEPGAPFVPHPEGYASAAELVAGLKAIAPFEISVAAYPETHPDAASAEADIDNLK
RKLDAGATRAISQFFFSPEAFFAFRDKCAAAGIDAPILPGILPVTNVAQARKFASACGAA
IPAWMDGLFEGLDEKPAARQLVAATVAAELCRRLYAGGVRDFHFYTLNRPELAYAICHML
GKRPQETGSVGDNA
>A0A8C4HBJ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dicentrarchus labrax|TrEMBL
MLLNERRSSKSDSSGASNSGGESSKDSSRCSTPVLDADRSDRLRDKMRKRMESGDRWFSL
EFFPPRTASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGL
ESILHLTCCNQTKEKITGYLAKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAIDLVKHI
RSEFDDYFDICVAGYPTGHPEAESYEGDLRHLKDKVDAGADFVITQLFFRADTFLKFLDD
CRAIGITCPILPGIFPIQGYQSLRQLVKLSKLEVPEEITKVIEPIKDNDAAIRNYGIQQA
VDMCRLLLDSGKVPGLHFYTLNREVATMEVLRQLGLWIEDPRRPLPWAVSAHPKRKVEDV
RPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKDALLQMWG
EELINEESVYEVFTCYITAQPNSRGHKVMCLPWNDEPLAPETNLLKDELEKVNRRGVLTI
NSQPNINGKPSTDPIVGWGPAGGYVFQKAYLEFFTSSENVTALLKVLKKYEPRVNYHIVD
VHGRNLTNAPDMQPNAVTWGIFPGREIVQPTVADPVSFMYWKDEAFALWIEQWAKLYEDE
SPSRMIIKYIRDNYFLVNLVDNDFPLENCLWQVIDDMFELLDASPEQTLGQ
>A0A657LYH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pararhizobium antarcticum|TrEMBL
MAHIDENPLGRDLPLDPLPGHSSRGRLERVLRRGEFAVTAELNPPDSANPQDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNGKFLSGRKLTTPPQVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCFDVPMFRTYMEKVRDLGLDEKCYILCGV
GPLASAKTARWIRSNVPGIHIPDSIIARLEGAQDQKKEGKQLCIDIINEVKEIAGVSGVH
VMAYRQEEYVAEIVHESGVLKGRTPWKRESNLGDALVAERMDALRDGKTENQEEMADVAA
HRPH
>A0A3N4Z2N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Georgenia muralis|TrEMBL
MSTSSLLAVPTTRPTVSFELYPPRRPELGEVVWQRILRLAEAGPDFFSVTYGASGSSRDA
SERLVRRILDETGVPVIAHLTCVGTTREELGALVRRLLGLGVRDFLALRGDPPAGQSVWA
PAAGGLARSSELVDLIRQVEAEELGAPRADGGREAGATTAEPSPVARELGVDPADVVSVA
VAAYPCGRSHTREAELAALREKQAAGADFAITQVFYDVDSYASLVADARAAGVLIPILPG
IIPLTDPGRLARLGELTGVDVPPALTALLAVDDETERLRRGVAATVDLVEGALAAGAPGL
HLYTFNRDRPALDVLEALRERGVSNPALPPSLRGDPARPGALPLERR
>A0A2P5M008|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystis sp|TrEMBL
RALIAATTAVEQVMSLARAGVNEFHFYTNNRADLVFAICHLLGVRPLREKALA
>A0A1V6QB39|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Penicillium solitum|TrEMBL
MEKKITEKIAALPPDANYFSLEFFPPKTRMGFANLSARLERMAQALRPLFVTVTWGAGGS
TAARSLELAEVCQRQLQLTTVLHLTCTNMSRKLVDMALDEAKALGIRNILALRGDPPRSE
EYNMHGEDDSNKDFTFAVDLVRYIRQTHGDYFCVGVAAYPEGHPADTFQDVQDPIRDIPY
LVEKTLAGADFIMTQLTYDIEAYQKFEHALRNHESGAFKTIPIIPGLMPIHSYKILTRVT
KLSHVTIPPPIARRMEELKHDDDAVKRAGVDIVSEIVGGIRDIPSPGPRGFHFYTLNLEK
TVSFILEQCDLIPSYSDAGELAIEDDPASIPLDFPGRALRRRRASSINSQPHNRVIVDKL
SVHESSQDSVHEALADSAGVPAPPPNRSTTLLISEGLGALGREATWDDFPNGRWGDARSP
AFGEIDGYGPSLHVTANSARRLWGNPVDSKDMSTLFRRHVSGDLHMVPWSEGGAEEDGDG
LNAETELIRPELLKLIDGRGWWTLASQPAVNGVHNDHPIFGWGPQREGFVFQKPFVEFFC
SSNDYTNILKPMFAKHGHDKLTWFATNIKGDFESSLPTQPADVELDDLGSNPESVNAVTW
GVFRGKEIVTPTIIEEVSFRAWGEEAFRIWDEWRRIYPRGSPSETYLDTTKNDSWLVCVV
GQQFGAGTKRGSKEEEDEVKWMWRVLAGEEA
>A0A411HN66|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudolysobacter antarcticus|TrEMBL
MTAISFEFFPPKTDEQRDTLDKSVAKLVALKPEYVSVTFGAGGSTLNYTHDTVVALKREH
ALDVAPHISCMGGTRAEIKSLLDNYVAAGIKRLIALRGDMPSGMAAFGEFHYASDLVKFI
RQETGDYFHVEVAAYPEFHPQAESAEADLKHFKHKVDAGADGAITQYFYTPDAYFRFVED
VRKLGITVPIVAGVMPISNYSQLRRFSEMCGAEIPRWMAKRLHAFGDDAESIREFGAEMV
ADLCYKLIAGGAPALHFYTLNRARATLAICERLGLSGA
>A0A2S5MYS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystis sp|TrEMBL
MFNALHPTASPNQFAISYEFFPPKTPEMETQLWQTINRLAALRPHFVSVTYGAGGTTRER
THSIVARIVRETEMKPAAHLTCVSAAREDIDAILRDYWDAGVRHIVALRGDPPTGVGSRF
EAHPKGYAHSTDLVSGIRRIGDFEISVSTYPEGHPESASIEQDLDALQAKVDAGATRAIT
QFFFDNDVYFKFLDKARGRGITIPIVPGIMPIRNFKQVAGFAQKAGASVPRWLAERFDGL
DEDPETRALIAATTAVEQVMSLARAGVNEFHFYTNNRADLVFAICHLLGVRPLREKALA
>A0A560F0N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirillum amazonense|TrEMBL
MTIVTETAADTPLARQLGGGEPLVTVPRDLRVSFEFFPPKTEKMEQTLWQAIRRLAPLSP
AFVSVTYGAGGSTRERTHATVTAIQQQTGIPAAAHLTCVAATKEEIDTIARAYWDAGIRH
IVALRGDPPQAADGSGGLGGSGYQPHPGGYAYATDLVAGLKRVADFEISVACFPETHPEA
ASAAADIDNLRRKVDAGATRAISQFFFDTDKFLRFRDTVAAAGIDIPIVPGILPITNFGR
AVELGAKCNCVVPAWMDELFGGLDAEPETRQLVAATVAVQQCLRLEREGVRDFHFYTLNR
ADLTVAICHMLGVRAPKAV
>A0A1V0TQ20|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces gilvosporeus|TrEMBL
MALGTASTRTDRAHTVRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWIKHPEGVGYAAELVQLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYFRLRDRVAAAGCSTPIIPEIMPVTNVRQIERFAQLSNAAF
PPELADRIMAVKDDPAAVRSIGIEYATELCASLMAEDIPGLHFITLNHSTATLEIYENLG
LHQRS
>A0A3S2A4R7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.US.005.03.2.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYM
>A0A3A9T0B8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. XB500-5|TrEMBL
MKIIDIIREKEVTLSFEVFPPKTDAGYAAVEEAAAEIAALKPDFMSVTYGAGGGTSKNTA
NISADLQNKYGVNVLSHLTCVSSTKEDVRSMISTYKEKGIENIMALRGDIPKEGRVCYDY
DHATQLIYDIKSVDDSLCIGGACYPEGHVECARQSEDIMHLKEKVEAGCDFLTTQMFFDN
STLYQFLYRIREKGIDVPVLPGIMPITNAKQVARSVALSGSTIPQKMKIMVDRFADNPEK
MKEAGIIYACDQIIDLISNGVSHIHVYSMNKPDIAAGMMRNLASIIR
>A0A1D2V8L2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ascoidea rubescens DSM 1968|TrEMBL
MKITDKLLKAHSNDYSFAQTNGIQHLNLNDQTDQTDQNDQNDQNKNSKESSSSSSSIFSS
LIEKSDLYQNNNHYNHTTFSFEFFPPKTSQGVQNLYDRIDRMYNLNPLFIDITWNAGGKV
SKLTNQIVNVTQSILGLETCMHLTCTNMSIDLIDNALLNAYSSGCQNILALRGDPPINDN
NNNSDSSAFDNGKFKYAKDLIKYIRSKYGDYFCIGVAGYPEGHPEESDSAVLLSYLKQKI
DAGGDFIITQMFYDVDNFLNWCNVLKNDWKISVPIIPGIMPISTYSSFIRRATWSHINIP
DSFLSVLKPFKDDDAKIKELGAELITEMCRTLIDSNLVNHLHFYTMNLESSTISILEKLN
LLNNFVINNSDNNENDDYFPWRKSLNPSRSTESIRPIFWQNKKFNYFIRTKNWDEFPNGR
WGNSNSPAFGEIDLFNGSLLRHSSNKILKLWDRPTSLNNLIQLFIDYLNGKLSMLPWCDS
PINSLEISDYLNNLIDLNFKGILTVNSQPKINGVKSTSKIHGWGPRNGFIYKKQYLEFFL
PKTHLNKLINKIQTCNDILNNNNSNYNISGKNNNNKNDDYNILSFFAVDNLGTFYSNLKD
LSKANAVTWGIFPNCEVIQPTIVEKVSFLAWKDEAYKLTEEWLLIYKNQNSQIDINKNEN
EKIYEDNLKSQKVLRNLIDNYVLVNIVDNDYVGNEKIFSLFDDFNCLEE
>A0A851IAV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptotrichia sp. oral taxon 223|TrEMBL
MKIKDMFEQKEHLISFEIFPPNKNFSQEKLKNVTAELVECKPDFISVTYGAGGKTKGGTI
EMASHIKNNLKTEVLAHLTCVGSKKSEIHDYLQEAKSCNIKNILALRGDVPQGETEEIYD
KGDYKYASELISDLRRNSEFNDFSIGGAFYPETHYENNDLVDLFHLKNKVEAGTDFLTSQ
MFFDNDVFVKFKEQAEKLNIKVPLVAGIMPVTNAKQIKRIIELAKCSVPHKLDKLLEKYG
DNPESMKKAGIMYASEQIIELLAYGIKGIHIYTMNKPEIAKEIMKNIEFAR
>A0A5B8RHF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured organism|TrEMBL
MNEAATTTTTAADAARACTALAAPRFELLPIKGVHERASALPAGATVTVTCSPRHGIERT
LDTAEGLAAAGFRVVPHVAARLIRDRHHLQAVLERMAAAGIDDCFVVGGDAERPAGPFPG
GVELLDTLAGASPRPARIGVPAYPEGHHRMDTRTLDAALSAKAANADYVVTQLCFESAPV
LAWLRRQRERGLTLPVLAGIPGVMDRRRLLSVAVRIGIGDSTRALGRQRGLVGRLIHSGE
YRGDDLVWGLVDGLGDPVQGLAGVHVYTFNEVAATRDWLTTLHDGLCQWHGLSAEAEVAA
GTAGVHAEQPG
>A0A737H3N8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. salamae serovar 42:f,g,t:--|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7W4K5U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconacetobacter tumulisoli|TrEMBL
MPFPLTAVRPLSHAPAPDPVGISFEFFPPKTAKAEDGLRQAVDALVPQAPRFLSVTYGAG
GSTRDRTLATVAALVRDTSVPVAAHLTCVDATRQEVDEVARTYWATGIRHIVALRGDPAT
AGSRFVPHPDGYENAAALVAGLRRIAPFEISVAAYPETHPDAASPRADLDNLKAKIDAGA
TRAITQFFFEAETFLRFRDKAAAAGIDAEILPGILPVANIAQAYKFAGMCGAHVPDWMRR
LFDGLDDQPATRALVTTAVAAELCRRLRAGGVSQFHFYTLNRAEACQALCRLLASPQ
>A0A7I6QVN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella sp. WP3-S18-ESBL-05|TrEMBL
MSFFHANQREALNQSLAEVAGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDASRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKDVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMSTMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A7C1SY13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Agrobacterium albertimagni|TrEMBL
AAMGVANIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRTMRDESKFLSGRKLTTPPKV
FLGAAINPFAPPYDFRPYRLGKKIEAGAQFVQSQYCFDVPMFRDYMNKVRDLGFHEKCYI
LVGVGPLASAKTAKWIRSNVPGIHIPDSVIARLEGAADQKKGGKQLCIDIINEVKEIEGV
SGVHVMAYRQEEYVAEIVHESGILKGRRPWKREHARADDIAAERMREIGADPVQDQQTLA
GLAANTQPH
>D7VL62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium spiritivorum ATCC 33861|TrEMBL
MKIIDHIQNAKGKTLFSFELLPPAKGQSIQSIYKTMDELMEFKPPFIDVTYHREDYLYKE
HANGLLERVSYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARRGDADFIPTEGGHSFATDLLEQVANMNQGRYLHEDIETSEKTNFCIGVAGY
PEKHFESPNFNTDFKFLKKKIEMGAEFIVTQMFFNVQKYKDFVTKCREHDINVPIIPGLK
PITSKKQLVTLPRVFHLDIPEELSDAIADCHTNADVRQVGQEWLVQQCKELIEFGAPVLH
FYTMSNPGPTKKIVEQLF
>A0A417K3S8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM27-16|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
EYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMLEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A1L8CH55|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Apilactobacillus kunkeei|TrEMBL
MPLQYSFEITPSIDRVNLDGLLNLNPEFISITDRNHDMDNLMQSIQISDYIHANSSVDVV
IHLTGIDKDEKRVKEMIDLMQQHDIHSVLALRGDKLSQNDTAVTFPHADRLIEFINQKYP
HVNISGTCYLNSSDEEMKWLRQKIEKGCTNLISQFSFDANDYVDYLNQIEIDTPIWFGIM
PVIGKSQTQKMLELTYSTAPDELNVLMTQHDDDFGEDGVKYTAGMINKIRQAGANHIHLY
SLNNAENTKRIINKI
>N8R843|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP-A165|TrEMBL
MTKRVPISFEFFPPKTDVGAEKLRTVHQELQRLNPEFFSITYGAGGSTRERTLAAIHDFN
GSGTPVAPHLSCIGDDKTRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREYSGDHFHIEVAAYPEMHPQAESFDVDIQRFVEKVHAGANAGITQFFFNPDAYFYFM
ERLDKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSKSIKAFGHE
VIVKLCERLIAGGAPSLHFYSMNQTEPTQQLVVDLGLN
>A0A1M7TC11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sacchari|TrEMBL
MDNPNFSIEFFPPKTPEGAEKLRATRTKLSALKPKYFSVTFGAGGTTQRGTLDTVVEILA
AGEDAAPHLSCVGGTRESIRDILAEFKSHNIKRIVALRGDLPSGYGAAGEFRYANELVEF
IRQETGDHFHIEVAAYPEVHPQARSPQDDLQAFERKIKAGANSAITQYFYNADAYFQFVE
QTNKLGINVPIVPGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTALCERLLKGGAPGLHFYSMNQAAATTALWQRLV
>A0A2W7B3A9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Snowella sp|TrEMBL
MLTQFRQAIASKDFLITAEVTPPKGGNPQRMLEVSQGLKGRVHAVNLTDGSRAVLRMSSL
AASLILQKHGIEPICQFTCRDRNIIGLQADLMGAYALGIGNILALTGDPMKAGDYPKAKA
VFDLESVRLLQLIEKLNSGFDHNQKPLPDEALDLLAGAAVDPQSPSWSGLQQRFERKLAA
GAQFFQSQLITDFDRFDKFMNQIAAGCEKPILAGIFLLKSAKNAQFINKNVPGVHIPDDI
IQRLAQASDPLQEGVKIAAEQVLLAKDLCQGVHLMAIKREDLVPQILDLAGIPPVKIY
>A0A1H5RVS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium urumqiense|TrEMBL
MKVTQHIEGAKGNTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYVD
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGIDN
VMALRGDAMKDEQYFIPKQGGNDFAVDLVKQINQLNCGKYLHDVMDVDNKANFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAVQKHLQVLPQIFRIDLPEDLIHAVDQCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASKVF
>A0A1Q5IGR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CB02115|TrEMBL
MRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSVTYGAGGSTRAGTVRA
TQQIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVRGDPPGDPMGEWVEHP
QGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSSDWETDIGHFVDKCRAGADYAITQMFF
RPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATVPASLKERILAAKDDP
AAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYEKLGLHKQS
>A0A2P8F2A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacterium halophilum|TrEMBL
MSESLQQKFADPHRSVCFVGTTPPKASTEDMQMQEIADRLLARLDTLEYDGLIVYDIQDE
SSRIDTPRPFPYMETRDPREYSKLLSQSSQRPIITYKSVAQRDRADFDQWLEEAWSDYDI
RNLVLVGSPSSEGDIKLSLNDAYAALKEHDKPFHLGGVTIAERHAVKGNEHQRLINKVEN
GCEFFVSQAVYNAQATIDLLTSYARSCREMGVTPKRIILTFSPCGSAKTLEFMEWLGISV
PEATRYRILDAEKPLAESIRICQNNLEQILDACLPLGLPIGLNIESLTNRKAEIDAAIHL
YQLLKATLDLRLAERHLNQAG
>A0A3D5G678|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcoleaceae bacterium UBA9251|TrEMBL
MNRFRTACTTPGEFIITAEVTPPKGGDMTHTLAMAQQLKNRVHAINITDGSRAVLRMCPL
AVSAILLQHGIEPICQVACRDRNQIGLQADLMGAQALGIRNVLALTGDPVKAGDHPKAKS
VFDFEAVRLLQTIQKMNGGTDWNDKRLTDGVTDLFAGAAVDPQSPSWSGLQSRFEKKIEA
GAQFFQSQLITDFELLDKFMHQIAAGCNKPILAGIFLFKSAKNAEFIKKYVPGVHIPQET
IDRLAKAPEPLQEGIKIAAEQVKLARQICQGVHMMAVKREDLIPQILDLAGIEPVS
>A0A434VNP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M1E.F.Ca.ET.063.01.1.1|TrEMBL
MIARQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGRFLSGRKLTTPPQVFL
GAAVNPFAPPYDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKAFMQSARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDAVIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVAERLDHILHDEITETQVDMVK
TAH
>A0A316P445|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prevotellaceae bacterium|TrEMBL
MDITNLLKNNESTAFSFEVLPPLKGKGLDTINNTIELLREFDPKYINITTHHSEVYFRDA
GNGLYQVERLRRRPGTVAVAAAIQNKYGIPVVPHVLCSGFTKEETEYLLIDLQFLGITNL
LLLRGDKAKEDKRFRPTEGGHEHTTDLEVQVNDYNNGKFVNGEKIEFIGEKFTYGVACYP
EKHEEASNMKTDMEYFKRKIELGANYGVTQMFFDNSKYFAFVEEARKAGIEVPIIPGIKP
FTKLSQLTVVPKTFRCDIPEEFVKEAAKCKNDDEFKELGVEWCVAQCKELMTHGVPSIHF
YTMGAANSIRRIAEKIY
>A0A7T4QVP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium sp. UDSM-2020|TrEMBL
MKIVDHISNAKGKTLFSFELLPPAKGQGIQSIFKTMDALMEFKPPFIDVTYHREDYMYKK
HESGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDPDFIPTEGGHAFATDLLQQVADMNQGQYLHEDIAISEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVNKCRENDIHIPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSEAVSGCKNNADVRQVGEEWLVQQCKELIDFGAPVLH
FYTMSNPGPTKSIVEKLF
>A0A2Z2K7J5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus donghaensis|TrEMBL
MKPDLRSAWGSKVLVGDGAMGTFLYQKGFPVGISYEELNLTSPGVIEDVHRSYMEAGAVL
LESNTFSANYDRLSKYGLESKVEEINRAGVRIARKAAGDTGYVVGAVGSIRSGKRANLSA
SELKRFFTQQLSALLEEEVDGIMLETFYDVEELHLALRTLRKLSQLPVICQLAVDETART
LDGLTLPEAFRILEDDGADVIGFNCNTGPNGIKRALRHLQGSLVLPVSVYPNAGVADYVD
GEYRYGASPEYFGQMAVTFAEMGSRIIGGCCGTTPQHIAEMAAALRNYQPQPLPEPTQRA
TASLILQEHLADAEGPSGKEPTLVDLVKERHTVIVELDPPRDLDIARFMKGAEALRKAGA
DALTLADNSLAVSRMSNMALGALVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGIDH
VLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDRGLIARVAEATAHLNIPIFIGIMPLASGRN
AEFLHNEVPGIQLTDEVRSRMSGLEGEVGRAEGVAIAKELLDEATAHFNGIYLMTPFMFY
EMSAQLVEYIWAKQGRKLSPLFR
>A0A7W1NIN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solirubrobacterales bacterium|TrEMBL
LLAAPGSLLAAGERVARRASAPSTRSTYLHAYRHFAGFLAARLGRAPEPTDLTEAALLDF
RDGLEAAGRAWATVAKELSALRRLPRRSSQRASTRFVRQPPRQAIACRAMPMTALTSAEI
SLPGAPEALRVRERIAALADTVDIVGLTDNHAGQARMSPLAAVALAREQGVATVVHVSCR
DRNRLALQSQVVGAAALGSEGILCLQGDPVDGVQRVKDLTATALIAEAHGWAAPRELAVG
AVVNPFAADVDREVRLLERKLAAGATFVQSQMCFDLDALRAFLERAGDLLDRVRFYAGVA
LLRNDRMADHVRALPGCVLPDAAHRQISLGGGLELATELAVELAAIEGVDALHLFPLGGE
ASIREIAVAYRTASGVPAQPP
>A0A417CTN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM42-11|TrEMBL
MKMKELFDRGEFAVSAEVGPPKGIHVDELVEEAKTYLTGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMFGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A101E8K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium 41_269|TrEMBL
MSLKTDSRLEKLLKDGHFVVTAEIGPPKNADASIVKNKARMLKGFIDAANITDNQTAVVR
LSSIASAVHVLDVEMEPVIQMTVRDRNRIGLQSDLLGAYSLGIKNVVCMSGDHQIIGNHP
ESKGVYDLDSIQLIQAVKNMRDKKEFINGELIQGTAPCFFIGAVASPFLQPEEMNLMRLE
KKIRAGADFIQTQCIYDMKKFEKWMSQVRDMELSSQAYFLAGLMPLKSSKVARYMQDNIP
GIGIPETIIRRMERAKEPAKEGIKLAVEQIHWLKTIEGVHGVHIMAVGWEEVVPEIVERA
GLLPRP
>A0A2S5P463|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobium sp|TrEMBL
MANVKERKSRLLGAGEIDVTFEFFPPKSEKMEEALWACVERLAPLRPEFVSVTYGAGGST
RERTHATVARIVKTTAMKPAAHLTCVNATRDEVDAVARAYWDAGVRHIVALRGDPSAGVG
ARYEPYPGGYANAAELVTGLKKIGNFEISVAGYPEKHPESPSVEADIDNLKAKIDAGADR
VITQFVFDTAHYLRYLERVRAAGIWVPVMPGIVPIHNFKQVAGFAAKTGATMPAWLARRF
DGLEDDHATTQMVAVAVAHDQVMDLVDEGIKKFHFYTLNRADLVYAVCHLLGLRPVKSAA
RANAA
>W4M1I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Entotheonella gemina|TrEMBL
MKIRDMYGRQQPVISFEFFPPKTQGGVTNLFKTVDTLRAYNPAFVSVTYGAGGSTRDKTV
DLVRRIKSELGIESMSHLSCVGATKADIDSTLDDLAAADIDNILALGGDPPRDQPMAERS
VWGFQHANELAAHIKTRQRFCIGGACYPEGHIDAPSKDIDLKYCKQKVDDGAEFLITQLF
FDNRDYIDFVERARAIGIEVPIVPGIMPVTNFTQIKRFAELCGATIPSQMSFDMAPVEDD
PDKVEALGIAYATQQCRELLDAGAPGFHFYTLNKSRAMSRILDHLKRG
>A0A4R1BAS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flaviaesturariibacter flavus|TrEMBL
MKVTEHLAQGKDRTLVSFEILPPLKGKGIKSLWEHLDPLMEYKPSFINVTYHRSESTFKR
RADGSFEKVQVRKRPGTVGICAALQNRYGVDAVAHLICGGFSKQETEDALIDLHFLGIDN
VLVLRGDAPKNEGVFMAEPGGHHYAIELLEQVMRMNNGQYLEEDLKNATHTDFCVGVAGY
PEKHFEAPNMTTDLAFLKAKVNAGACYVTTQMFFDNKKYFDYVEACRAAGINVPIIPGLK
PLTTKKQLTIIPRTFHVDIPEALASAVLACKTDADVEQVGTEWLLQQSRELKAAGVPVLH
YYTLGKPDVISNVVKEIV
>A0A5P9FJT6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseivivax sp. THAF30|TrEMBL
MTRPEISFEFFPPKNIEASFRLWDTVQTLAPLNPRFVSVTYGAGGTTRELTREAVSAIHK
HSGLRTAAHLTCVNATREETLGIARSFAEVGVTDIVALRGDPPKGETRFTPTDGGFANSC
ELIAALKETGDFTVRVGAYPDIHPEAPSDTADVEYLKRKFDAGADEAITQFFFEAETFFR
FRDACEKAGIDKPIVPGIFPIENWKGARRFAESCGTKIPAWVIEAFDAAERDGREDLLAT
ALCTELCTDLIEGGVDKLHFYTLNRPELTRDVCFALGVTPETRLENVA
>A0A553YWD4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. MZ03-48|TrEMBL
MALGTASTRTDRAHTVRELLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVAPTFVSV
TYGAGGTSRDGTVRATERIATDTTLTPVAHLTAVNHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVRHPQGITYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVAHFID
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCTTPIIPEIMPVTNIRQIERFAQLSNAAF
PPELADRILAVKDDPSAVRSIGIEYATELCARLRAEDVPGLHFITLNHSTATLEIYENLG
LHQQP
>Q82AF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)|TrEMBL
MALGTASTRTDRARTVRDMLASGKTTYSFEFSAPKTPKGERNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETEQIVADTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWEADVERFVD
KCRAGADYAITQMFFHPESYLRLRDRVAAAGCETPVIPEIMPVTSVKMLERLPQLSNAAI
PSVLQERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPQQA
>A0A1Q7V7Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium 13_1_20CM_4_56_7|TrEMBL
MPREFLARLKTSPMLCDGAMGTLLYSKGIFINRCYDELNISQPDLIRAIHHEYLQAGAEI
IETNTFGGNAVRLERHGLQDKVHDVNFQGARLAKEAAKSFDSWVAGAVGPLGIRIEPLGK
TSFQEARDIFREQIAALIEGGVDLLMLETFGYIDELHQAIHAARELDPRFPIVAQVTLDE
DSNCLDGSTPEIFAPRIEEWGADVIGCNCSVGPVSMLDSIERIRAATTLPLSAQPNAGIP
RSVEGRNIYLCSPEYMASYARKFVTAGVRLVGGCCGSTPEHIRVMKSALRVTQARARTGE
TAAKTQTAAPVVASIPMEQRSRLGAKIAHGEFLTMVEIVPPKGTNIQKELEGAKFLKSVG
VDAINIPDSPRASARMSNQALSLLLQQQAGIEAILHYTCRDRNVLCIQSDLLGAAAIGIR
NLICITGDPPKMGGYPDATAVFDVDAIGLVNIVHNLNRGLDIGGNPMGAGTGFVIGIGAN
PGVPNIDEEIGRFEYKVEAGAEYAVTQPVFDLSLLEKFLRRIQHFKIPVVAGIWPLVSAR
NAEFMKNELRVSVPESIMERMTRATSPEAAKEEGIAIAREMLIAVRHMVQGAQISAPQGK
YSAAVDVLEALGSSGAKAG
>A0A674AMS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmo trutta|TrEMBL
MVNNVQRVDDNWRTCTKSDSSGKRNSGGESSKESSRSSTPVLAADRTERLRDKMRRRTES
GDHWFSLEFFPPRTASGAVNLVSRSVANTNLPLDQAYGQSTFEMEIFDRMGSGGPLFIDI
TWHPAGDPGSDKETSSMMIASTAVNYCGLESILHLTCCNQTKETITGYLSKAKHLGLKNI
MALRGDPVGADWEEEEGGFNYATDLVKHIRCEFDDYFDICVAGYPTGHPEAESYDEDLRH
LKEKVDAGADFIITQLFFRTDTFLKFVRDCRAIGITCPILPGIFPIQGYQSLKQLVKLSK
LEVPEEIMQVIEPIKDNDAAIRNYGIEQTVGMCRVLLESGNVLGLHFYTLNREVATMEVL
RQLGLWIEDPRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSS
SPAFGELNDYYLFYLKSKSSKDALLKMWGEELTSEQSVYEVFTSYIKAQPNCAGHKVMCL
PWNDEPLAPETNLMMDKLDKVNRRGVLTINSQPTINGMPSDDPIVGWGPPGGYVFQKAYL
EFFTSSENVTVLLKVLKKYEPRVNYHIVNVHGQNTTNAHDMQPNAVTWGIFPGREIVQPT
VVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIKYIHDNYFLVNLVDNDFPLDNCLW
QVIDNMFELLDNPPEEQPTEQPAEQPAEESPVEDQPTK
>A0A5W5I755|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Cerro|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>M4ZTB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blattabacterium cuenoti BPAA|TrEMBL
MKVIEHIAKAKKSLFSFEILPPLRGRDIQDIFSTLDPLMEFCPPFIDVTYHREEFFYVKK
ENGLLQRKKISRRPGTVGICAAIMNKYGVDAVPHLICGGFSKQMTENALIDLNFLGIDNV
LVLRGDPLKSEKSFIAPENGHKYAVELVKQVKNLNLGKYLDTTFVEKKEFPLFDFCIGVA
GYPEKHLEAPNMESDLFFLKKKVEAGANYIVTQMFFDNKKFFSFVEKCRSEGISVPIIPG
IKPISSQKQLNSLPSRFYLNIPNELVKEVEKAKNKKNVSHIGIEWAIHQSKELKNSGAEV
IHYYTMDRPENIYKIVQAIY
>A0A5A9ZTA1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquicoccus porphyridii|TrEMBL
MTGPYPDPPAFVSFELFPPKTDAGETTLARAVDQMASADPAYFSVTYGAGGSTRDRTARV
VDMVGSRTGRPVAHHLTCVGASRGEVDRLARGLHDKGITRIVALRGDLPEGQRLAPDGYG
DAAELVAGLRRVADFDISVAAYPEVHPEAASAMADLDHLKRKLDAGAARAITQFTFDTDV
ILRFVERARAAGITAPIVPGIMPVANFAGLKRFSAMCGATVPDWLARMFEGLDDAPETRA
MVATSVATEQCRLLMEAGLSEFHFYTLNRPEVSLAVCRALGITPAVPAESAA
>A0A3D3RP81|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aquificaceae bacterium|TrEMBL
MKIGQYLKEGNFSLSFEFFPPKTPEGEEELFQTIKNLRSINPSFVSVTYGAGGSTRDRTR
RVVERIHKETDLTVMAHLTCIAHSKEELLQIIEEYREIGIENLLALRGDKPVNTPDFKPP
EGACKHADQLVSLIRENYGDWFSIGVASYPEGHPESPNMEWEIKYFKKKVEAGADFSITQ
MFFDNRYYYEFVDLCQKAGIDIPIIPGIMPITNFRQVQKFASMCGATIPQRLIERLEPYA
DSPEETLKIGVEFAIEQCLDLLENNVPGLHFYTLNKSKATLMVYEGIRGALKA
>A0A1J5CVL3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidia bacterium CG2_30_46_9|TrEMBL
MKTKSNLERVLESKNFAVTGELGPPQSADPEVIRRKARILKDHVDAFNVTDGQTAVVRMS
SWAACLIGKEQGLEPIVQMTCRDRNRIALQMDVLGVAALGINNILCLTGDHQKFGNHPTA
KGVYDIDSIQFVKMVKDMRDEKKFQCGEEMPVEPRLFIGAAANPFADPFEFRVIRLAKKV
AAGADFIQTQIVYNVDKFAEWMKMVCDKGLHEKVKILAGVAPIKSVGAARYMKTKVPGMD
VPDSVIERLRGVTKEQVPKEGIKLCVDIINQVRQIEGVAGIHLMAIEWEEAVPEIMEAAG
LLPRP
>A0A1G9BZ79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. YR527|TrEMBL
MVTGRGRSLAELINQGERSFSFEFFPPKDEAGEEQLWNAVRALEPYRPTFVSVTYGAGGS
TRDKTVAITGRIAAETELLPVAHLTCVGHTRDEVAGILDSYAAKGVAHVMALRGDPAEGP
RAEWTPTAGGLDYAIDVVKLARERGDFRIGVAAFPEGHPSAESLEADADVLVAKAKAGAE
FAVTQMFFRAADYFGLVDRVRARGVDIPILPGIMPILNLAAIRRQSELIGAEVPEEIVER
LGAAGPEAADIRAEGIVVAAELCQELLDGGAPGLHFYTLNRSKATLEIFAKLNVTV
>A0A2T4YH32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bosea sp. 124|TrEMBL
MTAFRPSRHGSRRPKVSFEFFPPKSEEMEVALWESVRRLEPLGPSFVSVTYGAGGSTRER
THSTVKRMVEETGLKPAAHLTCVSASRDEVDEVIRAYWDAGVRHVVALRGDPAGGLGTVY
EPHPQGYHQTSDLVAGLRRIGDFEVTVSAYPEKHPEAASLDADIEALKKKVDAGATRAIT
QFFFDNDVYFRYLDKVRAAGIDIPILPGIVPVQNFRQTANFARKTGASVPQWLADRFEGL
EEDAATRRLVAAAVCAEQALDLIDRGASDLHFYTMNKADLVYAICHLVGVKPEPAVAQAA
AAA
>A0A2V1K5P6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ancrocorticia populi|TrEMBL
MPPRRPDIAPKFWNTVTRLLETQPDFLSVTYGAAGQDRSTARQVVRRLVRDTPIQPIAHL
TCVRASREELVSVISDYLDSGVRTFLALRGDPPADDPTWRPAADGVNSAAELVNVIRTLE
QHRNIKQPGAGLRAAFKPLTIAVATFPSGNPEAGTSPEQEIERLLLKQVAGADFAITQLF
FEADDYIAFVEKARRYGVTIPIVAGILVPTEPRRLARVAELTKVVAPERLVNDLSRASDE
QDLYRRGIVHGSTLARQILDSGAPGIHFYTFNKAQPVLDLIDELPELTPTD
>H1KKL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylorubrum extorquens DSM 13060|TrEMBL
MPNASQHRASRDGFRPIRVSIEFFPPKTEEMEKILWSSIERLAPLQPKFVSVTYGAGGST
RERTHNTVARMVRETSLKPAAHLTCVDATKEEIDGVVQSYWEAGVRHIVALRGDPAEGVG
HSYRPHPGGYAQTCDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIEALKAKVDAGADQ
AITQFFFDNEIYLRYRDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLENDVETRRLVAAAVAAEQVLDLVDEGVEDFHFYSMNRSDLVYAICHLLGLRSQAPAK
PAVKPEAKAA
>A0A520R7L7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phycisphaeraceae bacterium|TrEMBL
MVVTQQVSYAKESFDLSFELFPPKTAESEAMLWQTVDELMGFDPTLITCTYGAGGSTQTK
TLEVLDGVLVRYPTVAVASHLTCVGRTTDQLREYLREAQQRGVTSIVALRGDPPQGETTF
TPIANGLHYAVELVALIKQEFPELRILVAGYPETHQEAVSPEVDLEHLKEKCNAGGDTVV
TQLFYDNTDFFRFRDRCSSIGITKPIIPGLMPVTNFKQIKRIATLCKARLPNSFTHALEK
AGDDADAQFEAGVDYASKQAEELLSNGIPGMHLYVLNKSPAAIRVLEQVGMTRP
>W1DT73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella pneumoniae IS43|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVEAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKVCGYDQCPYPGVDVKNVR
RAG
>A0A5M6B5P1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides caccae|TrEMBL
TFIREYNESGHHPDPGGFAIGVAGFPEGHPSTPNRLREMDFLKAKVDAGADYICTQLFFD
NHCFLDYRERCLLAGIKVPVLAGIMPVTSLSGMNRMAELSGGTCFPARLLKALKRTGGNP
DAIQEVGIQFASSQCAELLDAGVDGIHFYTLNQSRATRQIYRNLGLRDSLQLLEHGEDK
>W6N8V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium tyrobutyricum DIVETGP|TrEMBL
MLKDKILNRETGIITYAITPPKLNNLHQKIVEISQKQVERIKNIDVDGLIIYDIQDEIDR
QKEKRPFPFIETLDPALYNEEYLKNLTVPKIIYRCVGKYDENQFSKWIKSDKDSDRFSVF
VGASSSKQEVKLKLSEAYRISEQLNPNLILGGVVIPERHVTHKDEHIRIINKVGKGCKFF
VSQVIYNLENSKNFLSDYYYYCKNNNIEMKPIIFTITPCGSKKTLQFMKWLGINVPKWME
NDLMNSQDILHKSVSLSENIVEELLDFALEKDIPVGFNIESLSIRKVEIEASIKLVKDIK
SIIEKRLK
>A0A2D0I569|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuricurvum sp. PD_MW2|TrEMBL
MFETFIDKLRNSTYITLETTPSRSAQFAPTIEKIAALGLDQLVDGFSTTDNPLAKLKYNA
LFAAMKLQDRFGKPALATMSMRDRNRIALQSDLLGANESNVRTILALTGDSAHYSDQPHA
KGVFEGNSKLLLDIITTLNSGTDMAEQKLLAPVQEIYPFAVIDAYAKSAATLQKKMTKKV
AHGAIGIISQPVYDLENAQKLLTMMEEANRENNAECVLILGYFPITKLRTARFLDENVPG
IFVPHTWVEALETASLISPDEEYRIGFELSKNLFEELKALHPKIHIMTANQFELAKAILS
>A0A7H0I583|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces genisteinicus|TrEMBL
MRPGAGRFPATGPPAVSFSFEFFPPRTAQGERTLWETIRRVEPLAPDFVSVTYGAGGSSR
DRTVEVARRLVNETTLRPVAHLTAVGHSVAELRHVIGQYADAGVRDVLVLRGDPPGDPGA
PWIPHPSGFTHAHELVRLVKETGGFRVGVAAFPERHPRSPDWESDIRHFVAKCRAGADYA
ITQMFFHVEDYLRLRDRVAAAGCDTPVIPEIMPATDVRQVARFAELSGAAFPAPLARRLE
AARGNPAEGHRIGVEHATSMAERLLAEGAPGLHYITLNRSAATLDIHRNVTHSRSTQHVL
AVHR
>A0A840FCL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas jinjuensis|TrEMBL
MNTLSVNQLEEAQTALAGPLYADVGGDLEVSFEFFPPKSEKMEEQLWDAIRTLEPLGPRF
VSVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEATKEEIDQVAEEYWAAGVRHIV
ALRGDPPRAGEKYQTHPGGYENAAALVAGLKKLHPFEISVAAYPECHPDSADAAADLDNL
RAKMDAGATRAITQFFHEPETFFRYRDQVAAAGIDAEIVPGIMPVTNFAAVKRMSAMCGT
EVPAWLGRLFEGLDDHPASRQLVAATIAAELSRRLYAGGVKQLHFYTLNRAELAFAICHL
LGVRSRDEKAKAAA
>A0A7X4E904|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0673_bin_12|TrEMBL
MHIAEVFRQSQPAISFEFFPPKSEAASESLFHTIQKLIPLKPAYVSVTYGAGGSTRDLTH
DLVVKLHNETNLTIVSHLTCVQSSRDEIFRILQRYDEHSIRNIMALHGDPPSQEPCDPSG
QDFRHAVELVAFIKKHFPHMGIGVAGFPEGHPDTPNRLQEIEYLKAKVDAGADYVCTQLF
FDNRDFYDFCERCQLAGIHVPIIAGIMPITSLQGMKRMAELALGARFPGRLLRALASAKD
DAQAEKIGIHWATEQVLDLLDNKVLGVHLYTLNKSRASLQIYETLGLQRVDMLME
>D6KB79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. e14|TrEMBL
MALGTASTRTDRARTVRDMLATGKSTFSFEFWAPKTEKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPRGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVTAAGCETPVIPEVMPVTSVKMLERLPQLSNAVI
PDALKERILAAKDDPTAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A6B2P0N3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aliiroseovarius sp. PrR006|TrEMBL
MTTPNISFEFFPPQSLDASFRLWETVRQLAPLDPNFVSVTYGAGGTTRELTHDAVGTIHK
HYGLNVAAHLTCVEASREETLAIAKSYAEVGVKEIVALRGDAPKGADRFTAREDGFANSV
ELIEALANTGDFHIRVGAYPDPHPEAADLDADVAWLKRKVDAGAGSAITQFFFEADTFFR
FRDKCEKAGIDVPIIPGILPIENWKGVRKFAERCGATIPTWLDDAFHKAERDDRTDLLAT
ALCTELCSDLIDGGVEDLHFYTLNKPSLTRDVAHALGVTPQVSLAKVA
>V4JV35|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thiohalocapsa sp. PB-PSB1|TrEMBL
MDQRRRAIPLPTVPYPKHLRGATHANQSRAATLADSNTAMNTQGTDLATFSFELFPPKTT
EGMDKLKLAVEQLNAVRPRYFSCTYGAGGSTRERTFETVAWLRQQAIDTAPHLACIGSDK
DEVRNIARHYLEQGISRVVALRGDLPSGMGRLDSNTFRHANELVSFLRQEFGDQFHIEVA
AYPEIHPQAASAKIDLVNFKRKVDAGANAAITQYFYNADAYFRFVDDCADAGIDLPIVPG
IMPITNYTQLARFSDACGAEIPRWIRKRLEGFGEDKDSIRAFGHEVVIALCQDLLEGGAP
GLHFYTMNQPGPTLRLWEELALSHADQ
>A0A1F3WBN5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium RIFCSPHIGHO2_02_FULL_44_7|TrEMBL
MKVTDHLKQAKSTLFSFEILPPLKGKSIQSIYDGIDPLMEFGPKFVNVTYHREEFIYKER
ENGLLEKIAIRKRPGTVGICAAIMNKYQVDAVPHLICGGFSQEETENALIDLQFLGVDNV
LALRGDSIKTESAFRPHKDGHEFAVDLIHQISEMNQGNYLMDDVNLEPTDFCIGAAGYPE
KHFEAMNLSTDLGYLKDKVDAGAEYIVTQMFFDNKKYFAFVKACRAAGIQVPIIPGIKPI
KTLKHISFLPKFFHIDYPEELSKDLLKCTTNEQVSNLGIEWGIHQSKELKEAGVPCIHYY
TMSNSASVKAIAKEIY
>A0A2E6YQD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halieaceae bacterium|TrEMBL
MKFDDEPTPGENLPILPGHTSPGRFERVLRAGQFAVTAEIAPPDSADPEDVYERAALFDG
YVDAINATDSSGANCHMSSMGICSLLTRRGYAMILQQSCRDRNRIAMQGDILGAAAMGVC
NILCLSGDGVQSGDHPQAKPVFDMDSISALGMVRHMRDEQQFLSGRAISSPPRLFLGGAA
NPFAPPLDFRPHRMAKKIAAGAQFIQTQYCFDIERMKTFMAQVRDMGLLEKAYVLAGVGP
LASAKAAEWIRKNVAGVHIPDDVIERLAGAEDQKQEGVDLCVDLIEQVREIEGVSGVHIM
AYRMEDRIGEMVTRSNALGGREPWRPAA
>A0A374BIN6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM47-2BH|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKKRVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>D4TXZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schaalia odontolytica F0309|TrEMBL
MPFSDDTYACPCTHDHEPTLLSFEVMPPRRPSLEEPFWNTVDQLLRVRPDFMSVTYGAGG
KDRSNARSTVHRLVRDTPIQPIAHLTCVGNSTEEVVSTVYDYLDSGVRTFLALRGDPPVG
QDGWEPGPGGVGSATELIHLIRTVEKRRCDAHPGEALRSAFKPLTIAVAAFPAGNPAAGT
TPAQEVERLLVKQAAGASFAITQLFWDAEVYASFVERARRAGVTIPIVPGLLPATDPARL
RRVQDLTGIEVPEYLLTTLADYPRQDARDEFGAVFGSRLIHSVLEAGAPGVHLYTFNRSK
PVLDILALMGVKPDPLRSQASSPETRA
>A0A0U5AYZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldimicrobium thiodismutans|TrEMBL
MPHSFKSLLKERDFLFTFELVPGRSVRTRHYQEILRFLEESTNLKIFQAFSITDNAGGHP
ALSPIPLGRTIKEFGLEPIIHFSCKDKNRNQLESELLALDREGLHNLLVLTGDYPFYGYL
GRAKPVFDLDSVLLLKMITDMESGIELPRGAPGGGVRLPGIPFFKGAVVNPFKLTLSELW
WQYLKLYKKLQAGAYFIITQVGFYPRKWLELKNLLELGITKIFSQFLKDQSLHEPEKDKT
FERVPLIGSVLYLTPQLLRALKKGRIPGIFVTEDLLRRLEKASSFEEGALEISAELTAIL
KGLGYKGVHLCGFPLDYKLIEAFLEKVSKYETKWEGSFEELGNTALIELPQGVYQREIPC
LLKNGFDLRFEGKKSLFYLFNEAMHRLFFNRGNFLYPYLQKVAQFLDRYPRLKGYFTSLE
YFIKKLLFNCQECGDCTLWEFNYACPQSGCAKYLLNGPCGGSLAGFCEVYPFVKKCHFVR
AMERAPSQRELKKFIKSYLPPRDWALYKSSSWLNFFLRRDHTKDETI
>A0A7Y1W178|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MNTFRSAAQSKAFTLSAELTLKRGSNAADVRAQADLLRGRVSGVQVADNPLAWVHMSPLA
AASLLLDAGVDPVPILSCRDRNRIALMSDLLGLRAMGVTSLLLMRGRRVPRKHALHANTV
FDLSGRELIAMAAGLDTDAEAPPPFFIGTGVKAHRAKPGWRAESLQAKARAGAQYVQTQV
CYDLDILRHYMDRLVQARATWDYSVMVSLAPLDSARTARWVSKHMPDSKIPDALVTRLEQ
ASDPEQEGIRICAETMREIATIPGVSGVHLMTTGTPEHLAAAIDESGLGGERADG
>A0A2V8YZZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKIYDFNERLKDAILIADGAMGSMLHEAVGPQRCFDELNATEPEAVFRVHQAYIEAGAQI
IETNTFGANRFKLAPLGLGDEVQRFNSRGVKIAREARESAAREVLIAGSIGPLGLGVQAR
HPDDKEILDVFYEQALALEERGVDFYILETFSYIEEILLAVDAIRSFSGLPIVAQLTYSE
EGTTHGDIRPSDAAAQLKSKNVQVIGANCTLGPQALLPILQELAAVDDSRTSGMPNAGFP
KREGDRIVYPKSSPQYFALFAREAAALGVRILGGCCGTTPAHIQAMAEAVKSLRPAKAHA
TSPVAVEAVAKPAAVSQREPESRFWKKLRKKEFTICVEIDPPKGLALDRIFEQVDKVMAS
RKIDAIDINSGAMARVGMDALVVAGALEARGVETIPHLTTRDQNIIGLQAALLGAWTVGG
VRNVLAITGDPPSVGDYPETSGVYEVDSVGLVKVLSRLNQGTDWAGKTLGGATNFAIGVA
LNPVADDLDNEIARFHAKVEAGAHYAMTQPLFDPEHWHAFLKKLGDKPPIPILIGVWPLN
SYKQALRLNNEVPGMVIPEALLKSMEAAGAAARDCGFQVARQMLAWARSELAGAYLIPPF
KRYEEILEIL
>A0A2V9LPB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MREPFGERLEKRVVVCDGAMGTMLYSKGISLSRCFDELNLSAPHLVKEVHLGYVKAGAEV
VETNTFGATRLRLAKFDLGDKVREINIAGARLAREVAGDDLWVAGAVGPFGLRLEPLGPT
SREEARQSFREQIEALVEGGVDLVIIETMVDVEEAHQALLAARDASRLPVVVQMTIREDG
ATPTGTPPEDFARLLDEWGTDVIGLNCSVGPAAVLETLERMARVTAKKLSAQPNAGMPRT
VEGRAIYLCSPEYMASYAARFIQAGARLVGGCCGTTPEHIRAIKTAVKSATLGDSRAVVE
VVGRRLEAPEPPPVEQRSPLGRKLAAGGFPVIVEIVPPKGSDAAQEIEGARYLAAHGVDA
VNIPDGTGATARMSAISLAAILKQQVGVDVLLHYSTRDRNVLTIQSELLGAYALGLRNIL
ALTRDTAQYSTVQESAIFEVDAIGLVNILNSLNRGLDVGANPLGAQTGFLIGAALNPQAV
NLDEELRRFEYKLKAGANFALTQPVFDAQGLGEFLKPVRAMTHGKFSIVASLWPITSFRN
AEFLNNEVPGVTIPQPVMERMRKADTGDRARAEGVRIAQEILAEIREFVEGVQIASPFGR
YALAVEVAEVLKKDVVSSP
>M0PJ61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halorubrum kocurii JCM 14978|TrEMBL
MEQTVEKTELAREHGYEVVPHVAARFVEDADELDRIAGRLKQAGVTDIFVPGGDRDEPIG
EFESALDVLLELERLGYEFEEVGIGGYPTGHSEIAAEILDEAMQRKAPHATYLVTQMCFD
AEAIVDWIDGVRDRGIELPVETGIPGVMEYRQLMTLARRWGVAGPLSFARKTAGVFTFLR
MLIGSGGHYKPDDMLPVIAPSLEDPHYNIRRLRLYTFNQTRTTESWRRDWLDK
>A0A2V9F2L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKILDFNERVKDAILIADGAMGSMLYEAVGTQRCFDELNATEPEAVFRVHQAYIEAGAQI
IETNTFGANRFKLAPLGLAEEVQRLNSRGVKIAREARESAAREVLIAGSIGPLGLGVQSR
HPADDEILDIFHEQALALEERGVDLYVLETFSYIEELLLAIDAIRSFSGLPIVAQLTYAE
EGTIYGDLRPSDAAAQLKDKNVQVIGANCTLGPQALLPILQELAAVDGLRVSGMPNAGFP
KREGDRIVYPKSSPEYFALFAREAAGLGVRILGGCCGTTPAHIRAMAEAVKSLRPAKTHA
VAHSVATMAKPAPVSEREPESKFWKKLQAKQFALCVEIDPPKGLSLDRIFEQVDRVMASK
KVDAIDINSGAMARVGMDALIVAGALEARGVETVPHLTTRDQNIIGLQAALLGAWTVGGV
RNVLAITGDPPSVGDYPETSGVYEVDSVGLVKVLHRLNQGTDWAGKTLGGATNFTIGVAL
NPVADDLDNEIERFHAKIEAGAHFAMTQPLFDPEHWQAFLKKLGGKPSIPVCIGIWPLNS
YKQALRLNNEVPGIVIPERLLKFMEAAGASARDCGFKVARDMLAWSRTELAGAYLIPPFK
RYEEILEIL
>A0A2V8JJV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKDFLSSLQDRVLICDGAMGTMLYSKGIFISRCFDELNLSKPELVREVHLDYVKAGVDII
ETNTFGGNRTKLMSHALEAETREINVQGARIARQAAGSDIFVAGAIGPLGVRIEPWGKTS
IDEARAIFRDQAEALLEGGVDIFILETFSDLNEVLAAIQGIRDASNRPLVAQMSIEEDGN
SLEGTPPEVFARRLDESGADVLGLNCSVGPHTMLENIERIASVTSKKLSVQPNAGKPKNI
EGRNIYLCSPEYMASYARKFVQYGVRIVGGCCGTTPQHIKAIRSSVRSISPSFQPAPAPS
RLPSTVAETAATSLERGPRESSNAIPLEHRSRLGSKIARGEFIRIVEMIPPMGHDFSEAI
ERAKYLQAHDVDAINVTDAPRSSARMNAISLAILLEESTEIESLAHYTCRDRNLLGMQAD
LLGAYALGLRNLLLITGDPQLTGDYIDATAVFDVDSIGLTNMVRRLNHGIDVGGKSIGKP
TGFVIGVGANPGAINDDEELKRFHYKVEAGAQFVLTQPVFDPAVLEHFWRRIEDCKIPVI
AGILPLANYHTAEFLNHEVPGCAVPDSILERMRKADSPEKARAEGIRIAQDILETVQGTV
QGVHVRGPFEQYETPVEVLSVLNLKGASR
>A0A5N9I8R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MN1F|TrEMBL
MSLLKAALRDNHFVCVMEFVPKPSAERFAAMEAIMARGQLCGWPMTVAIGDRVGSPLDMS
PLDALASFNTPLPALPHFSGKDRERHHLLAQLQRMDAAGLDQLLLLTGDRLPGHQPGERP
VRYLESVAALLIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DASKHQEAIHWMQRQAAPKPMLACLMSLTHGRAAMLEHVAGVTVTPSMNDLLEAESQVSK
AFAQARSVDRLALQIIGVKLMGYAGVHLSGIHELKQLRALEERLEHWQAQIHSLEHWAPA
WADSWQMPGLPIVTFHPPQGNWRRGESTVTASSKEKARYHVLHAAHSLLFSRANWLSKAF
GWAVRQPLWATRRGARVLHGLERAVKRPLTGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSVKYRTAKAVRQTAVLTERLIPCIEVQTRHRSSWPQWFEAQPP
RPLSPQPAPRTQPES
>A0A7W0L6F6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MAGTVREQLAAGVPTFSFEFFPPRDEASEAVLWRTLRELERLRPSFVSVTYGAGGTTREG
TVRVTERIATQTTMLPMAHLTAVNHSVAELRNVIGRFAAVGVRNILAIRGDPPGDPTAEW
LKHPEGIEFADELVSMVRRAGQFCVGVAAFPYKHPRSTDVDGDARHFVEKVRAGADFAIT
QMFFDAEDYLRLRDRVAALGCDIPIIPGIMPVTSMGTIQRAPKLSGAPFPPGLASTFDAI
AEDKDAVRAQGIDQASELCQRLLDEGAPGIHFITLNRSTATREIWANLRETSPVG
>A0A2V8RYQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MNDFREILDSEHVYVFDGAVGTRLYDKGVYINRSYDELNLTQPDLVREVHEEYIKAGSEI
IETNTFGATRHKLQPYGLETKVRDINIAAVKIAREAAGDRAFVAGAIGPLGLRIEPFGPT
SFDEAKEMFKEQVEGLLEGGVDLFVLETFSELPVIEQAIRAVRELSDLPIIAQMAIQMDG
KTTFGTTPEVFTARLDELDVDVIGLNCGMGPNHVLNALEKMRPFTSKKLSAQPNAGLPRD
VQGRQFYMGSPDYMAEFSRRFVQAGASFVGGCCGTTPTHIKLIAEAIRSVSPRQAISEAR
KDSARVADLTPVDVQVVPAEERSNWGRKIARGEFVTSVEVLPPKGCDAQKTLDSIRLLKD
AGVDGVNIPDGPRAQTRMSAQATAVLVEREIGIEAVLHYCCRDRNLLGMMSDLLGAAALG
LRNLLLITGDPPKMGPYPDATAVFDIDALDIGNNPIGKPTAFSIGVGVNPGAVNLDEEIR
RFEWKVEAGAEYAITQPVFDTGQLRTFLEKISHVKIPIVAGIWPLISFRNAEFMHNEVPG
VNVTPDILERMRVASEKSKEHARDEGIAIARDSLLEVRNVIQGVQVSAPFGNVKYALQVF
DVLDEFNSTGAEASLPA
>A0A2V9LDQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MREPFLERLEQRPLISDGAMGTMLYSKGIPFSRCFDELNLSMPQLVKEVHLGYVKAGAEV
VETNTFGATSSRLKKFELGEQVREINLAGARLAREVAGDDLYVAGSVGPLGIPLEPLGPT
SLEEAREIFRQQIAALVEGGVDLIVIETMVDLQEARQALLAARDVAPLPLVVQMTIQDDG
STPTGALPEDFTRQLDGWGADVIGLNCSAGPAGILETLERMARVTAKKLSAQPNAGLPRT
VDGRSIYLCSPEYMASYARRFIEVGVRLVGGCCGTTPEHIKAIKAAVRSLRPQPARAAAD
VRSRPVEVMQPVPLERRSSLAGKLAAGEFPVLAEIVPPKGCDPTREVEGALYLRDQSVDA
VNISDGAGSTARMSAQTLAAIIQQRVSIEVLLQYSCFHRNVLGIQSDLLGAYALGLRNIL
AVTGQPPVLGTYPAATAVLDVDSIGLVNVLNNLNRGLDVGGNPMGTQTGFLIGVEVNPYA
LDVEEESRRFQFKVEAGANFAVTQPVFDAEHLARFLKRIKSAGIARIPILAGVYPLTSFR
NAEFLNNEVPGVSVPPAVMERMRKADTGDQARAEGVKVARELLGEIRHLVQGVQISAPFG
RYAMAVEVASVLREHAEAANDQPSVAGRRAEG
>A0A7W1SDC3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTLREALASGNPVIAAELRPPRAELEAAASMDAWIDTYHAVRGLTRGGTYVFLTDSAVGA
KEEDNLRHLVINLGTDVPRSRVVPFLTCKHPPEYCLNYADRAHQHGFDALVVLGGDKSIG
EPRCVEHAWQLREQIRRRVPALSLGGWANPHREPAAQVGHLLDDSATAEFYLTQIVSHHS
RDKVARFQEEAARRGLNLPGIFGVFYYRSANARTLSALSHFLPVPIQELTREFDAGASPE
EVCARSIRGLLEAGVRHFYVSNLPIGRAALTLQRIVALATPSTSVVSRPPL
>G4M5A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Paraburkholderia kirkii UZHbot1|TrEMBL
MQPIELSFEFFPPKTQEGVAKLRASRAELKTLSPKFVSVTFGAGGSTQQGTLDTVLEMAT
EGFEAAPHLSCIGSSKENLRAILSNYREHGIRHIVALRGDLPSGMGEVGELRYASELVAF
IRQEHGDWFKIEVAAYPEFHPQSRSPRADLENFTRKVKAGANSAITQYFFNADSYFRFVE
EAKKLGVDLPIVPGIMPITNFSQLMRFSDMCGAEVPKWIARRLESFGDNRESIRAFGVDV
VTSLCRRLIDEGAPGLHFYTLNGAWASKTICERLGFKSALIAPMPSPRAARRAVFSLPL
>A0A7W0XTX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geodermatophilaceae bacterium|TrEMBL
MQAVTRSIAERLRGDGPSFSFEFFPPRDEASERQLWQSLRELERLRPAFVSVTYGAGGST
REGTVRVTERIATHTTMLPMAHLTAVNHSVAELRHVIGRFADAGVRNVLVIRGDPPGNPT
AAWVRHPAGVEYAEDLVRLVKSSGDFNVGVAAFPHKHPRSPDFASDAKYLARKIDAGADF
AITQMFFEAEDYLRLRDRLSSLGYDVPLIPGIMPVTTMRTIERSEQLSGAPFPERLRGQF
ADLGEDRAAVRALGIEQAGRLCRRLLAEGAPGIHFITLNRSTATREIWTSLQETVPA
>A0A7Y4WXL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MKNFRELLESDSVYVFDGAVGTRLYDKGIYINRSYDELNLTSPDLVREVHEEYVKAGADI
IESNSFGATRHKLQPYGHEGKLREINIAAARIAREAAGDKVFVAGAIGPLGLRIEPYGPT
SFDEAKDLYKEQVAALLEGGVDLFVLETFSELPVIEQAIRAVRELSDLPIVAQMTIQMDG
KTTFGTSPESFTKKLDELGADVIGLNCGMGPNHILSALEKMRAVTDKPLSAQPNAGLPRD
VQGRQFYMGSPEYMAEFSRRFVQSGAKFVGGCCGTTPTHIKLVASAIRADSPRQTARNFV
HQPSSVAELKPEDVQVVPAEDRSKWSRKIARGEFVTSVEVLPAKGCDAAKTLESIGLLKE
AGVDAVNIPDGPRAQTRMSAQATAVLVEQTVGIEAVLHYCCRDRNLLGMMSDLLGAAALG
LHNLLIITGDPPKMGPYPDATAVFDIDSIGLTNMVNKLNHGLDLGNNSIGQPTAFSIGVG
VNPGAVNLDEEIRRFEWKVEAGAEYAITQPVFDTEQLRTFLDKIAHVKIPIVAGIWPLIS
FRNAEFLHNEVPGVNVTPEILDRMRTASDKSKEAAREEGIAIARESLLDVKDVIAGVQVS
APFGNVKYALQVFDVLEEFKERPREAVSVQ
>A0A7W1TS71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
LDQERRRFGFKLDAGAEFVVLPAVFDLDGINAVMPELASAGKPVLAGLHVLADSREAEFL
ANEVPGARVPESLVARLRTAEAEGRGTEEGLRIALQVAEGLRGRVAGLVVSGAGNLMEAV
AAIRAKLL
>A0A522Q1R9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MREPILQRLEKRPLVCDGAMGTMLYARGVSLNRSFDELNLVSPHMVKEVHMGYVKAGAEL
LETNTFGANRFRLAKFDLAEKVREINLAGARLARESAGEDLYVGGSVGPLGLRLEPLGPT
SLTEARNAFREQVEALAEGGVDLIIIETMMDLEEAHQALLAVREATSLPAVVQMTVQEDG
NTLSGASPEDFARQLDTWGADVIGVNCGMGPATVLETLERMATATTRKLSAQPNAGLPHS
IDGRTHYLCSPEYMAERASRFIQAGARIVGGCCGTTPEHIKAIKTAVKSLGPQAERVAIG
TTLRPLQALEPAPIKLRSHLAEKLVRGEFPVVVEIVPPKGCDPAREVEGAQYLKQNGIDA
VNIPDGSGATARMSAQTLAVVIQQQAGIETLLHFSCRGRNVLSLQSDILGAHALGIRNVW
AVTGDSPQIATLPSATAVFDVDAIGLVNVLSNLNRGLDMSGNPLGTQTSFLIGVGLNPNA
LDPDEELRRFEYKIKAGANFGVIRPVFDVDRLAGFLRRTQALDVPKIPLLAGIHPLTSYR
NAEFLNNEVPGMSVSPEILMRMRKVDTGEKARAEGLKIAREMLQEVHELVQGVQIVAPFS
RYAMAVEVVEALGARVHAAKGETALPEARGEASTV
>A0A2G2GWU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alcanivorax sp|TrEMBL
MQRISFEFFPPKTEQGKEKLLATQKKLLAKNPAFFSCTFGAGGSTRDNTRDMVNKLREQH
GDTAPHLSCIGQSKEEILELVNGYKDAGVTRIVALRGDLPSGMGYAQSEIKYADELVALI
RQETGDHFQLEVAAYPEMHPQARSFEDDIAHFKRKMDAGANSGLTQYFYNADAYGYYMDA
LQKTGCDAPVYPGIMPILNVANLLRFSNTCGADVPRWLQSKLNDIKDDDAAVKAFGEEVV
TRLCERLLAMGAPGLHFYTMNQAGPNLRILDNLGM
>A0A2V8JHT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MNCNKDNGYNGGRECESVGRRDRSGYLPGEQPPAEEATEAGPIVNKRFVQNFVRDYSLET
TVLQARRIPRFAAVVPPGTRIYIPHTPRTQLRDTVELATRLRNESMEPVPHIVARRVASL
SVLDDFLGRLAGEAGVNRILVVAGDIAKPSGQLGNALQILESGLLEKHGIRTVGVAGHPE
GHREVGDAVLRDALKRKKVYAEQSGASVYIVTQFTFSAAPIIAWEASHRDEIGRLPITAG
LPGLATARTLLKYAVECGIGASLEAFSKRYDSLTKLLTMSAPDETIVELVRYKERTPQSR
IAGIHFFTFGGFEKTAAWVNQVASGNFEVTEDGKLVLI
>A0A2M8CPE2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium CG_4_9_14_3_um_filter_57_17|TrEMBL
MHIAEILKQPGTHFSFEFFPPKTTEAAQTLFESIQELTPLNPSYVSVTYGAGGSAHRLTS
EVVIRLQKETHLTVVAHLTAVGASRNEIYHLLETYVNSGIRNVMVLRGDPPRNQPDYTPA
ADGFQHAAEMVAFIKKYFPSLGVGVAGFPEGHPETPNRLKEMDYLKAKVDAGADYICTQL
FFDNRDYFDFCERCEIVGITIPIIAGLMPVTTRHGLTRMADLALGARIPAKLLRAVLRAE
SDEAVERVGVYWATQQAFDLYDRNVAGIHFYTLNRSKPTLRIYEALAVTTR
>A0A4Y8V658|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas kribbensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGNHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSLSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A1F4FT49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_65_14|TrEMBL
MASNLQARLESGDFVVTAEITPPVSTDPGEFISRAMPLKGLVTAVNVTDGAGAKVHLSSL
AAAHFLVQSGIEPIFQMTCRDRNRLALQADILGAASLGIRNMLMLAGDDPKAGDQPDAKP
VFDLGSRSLIAMANRMRSAHELPSGTPIKGKLDLVLGAADVPIDPPPGWEPKGLRAKARA
GADFVQTQFCMDVGVVRRYAARLREQGFNLPILIGVAPIPSARSARWMREKLFGTLIPDA
IIERLEGAADARREGRRICVEVLQELADTPGVAGAHVMAPLNFAEIPAAIEESGVTRRKR
KT
>A0A1H0ZWV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chryseobacterium soldanellicola|TrEMBL
MKITDHIKNANGKPLFSLEVVPPQKGIGIEDLYKNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLMERRITRMRPGTLGICAAIQHKYNVDTVPHLLCGGFTKEETEYLLVDCMYLGIDN
IMALRGDAMKGHQYFEATPGGHSSAMDLVHQINNLGRGKYLHDDDQICDEHNKFCIGVAG
YPEKHMEAPSMNYDLKWLKQKVDAGADYIVTQMFFDNKKYIEFVTKAREMGITVPIIPGI
KPIATKRHLKLLPQVFKIDLPEELINEVESAKNNEAVKEIGIEWAINQCKELLDFGVPVL
HFYSMGKSDNIKKVAGELF
>A0A399YPG4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MTLTQQRLGSPPRISVELVPRSAASLTAEVGDIAAKLPWVTTINVPDLLKFDLRSWDACG
VVRGLPGPAGGDGTAYPAIPHVRAADVDPEAPLPMAGAIREHGIREVLVVSGDDADYFSQ
STYPVDAVDVIRRFRTELPEVRVYAGLDPYRNGVAAEMRYLERKLAAGAVGVFTQPFFDT
AFMRAWAGLLPDGIEVWWGATTVTSPASVGYWRRRNLVAFPRSFEPSIEWQRDYARQALD
VAGEHGHNVYLMPVRTAVLDYLDGLL
>A0A2M7PMQ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium CG_4_10_14_3_um_filter_34_13|TrEMBL
MIHHIQNKIYHIEVLPPKQDSEKLEKDLEIFSNKYLRVMDSSYCTCITDNTMGLLSFQGT
EIIEELDLPVMSEQVMIHLNTFHTKDDLDNILDICKSKGIRYLLIITGDGSERLPKLQPS
DVGATDVESVTSVELLKYINHEYPDTFVLGAAFNPYEPEEHEFEKMKRKMKAGATYIITQ
PLIERNEVVDRLLEKYPEIPVIIGTWMSRKLHLLSEAVGYEIPGNAEYDPISTLKMLHKL
YPGCGVYLSLLGFKTQYDLIKDIWV
>C5BVR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432)|TrEMBL
MTTSTLYTPARPTISFELYPPRTPAGEERAWETVEALVGADPDYFSVTYGASGSTATASQ
SLVRRILTETDVPAVAHLTCVGLSREHARDVVGGFLDDGVRDFLALRGDPPAGNPDWRPA
PGGLARACDLVALIRDLEDERFAGNAHADVANRLSIAVAAYPGMQEHPGAEFRVRDCDLE
ALVAKQRCGADYAITQVFFDVRAYTALVDAARGAGVRIPLVPGVLPLTDPRRIRRLCELN
AIPLPAELLARLDAADDEERVAIGLTATLALVADLLAAGAPGIHLYTFNRAEASLAVLEH
AFGRVPGAARPGSAAPPSPDHAAPQALVAALPRRGNA
>A0A0N1PCY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptomonas seymouri|TrEMBL
MVKITEAIKQATENNRNFVSFEFVAPTTEASIITLYDRIERLSALDPLFCSITWGEGGRT
AETSIEVASTCQSLLSINHQVNLTGYASEPEEVLKWLTILKVKGVHNLLITRGASANNAI
IETSSTSVATCNASDNGNAVRRAAGEDAGTALGSAPSSSPASPAFPHAVDLVRFVRQHFG
DFFGIAVVAFPEGEGSSPNDVAWTAEGEECELRFLKEKVAAGADYIITNSIFDVKVFDHF
CKQCHRHEIRVPILPGVLPVSQLRQLSAFGLRRLSGTASFIQKMEATEGSESETRRVVVS
FYQDLVKELLKRGCGGVHFFTINADNLLLAILKGIEVATHRMFPWRPSENEERRRQETVR
PVHWSSRVTSYMVRTAQWQDRNPGKWNPVSGSHHSTALALGEASGYHARLLLRSRAKRCT
QFLVLQGMPDIQTALTELSRIFVGFLDGNGTLPWADELSGETAYVGEHLLKPLNARGLYT
INSQPPVNGAPSSHKVVGWGPDDGCVYQKSYLEFFCPLTVAQTVFTTLEKYSSLQYMAMS
SQGSMVRARWRMDGDEGDHAEASPPQDGESVPILISPTPQQHDKISLFGVGVTAVTWGVF
PGREVIQPTIVSVDSLRAWVGEAFDLWAAPFPNNDVPAVVRYIQSEWVLVSVVDNVYQVT
PTPLENAVVEICSKIPPLVPIDLSQMRQPATSLAFPATAGVEVNTLGTFVRSI
>A0A2V8FB90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MSADVLTALTDGTFTFAAELRPPRAELADREGMDAWIDTYHAVRGLTRHGTYVFLTDSAV
GANEEDNLRHMVANLGRDVPREHVVPFLTTKHSLEYCLSYAERARQSGFPALVVLGGDRS
VGGKRCVEHAWQLRERLRAQDPALKLGGWANPHADPQRQVEFLTAPQFNAEFYLTQVVSH
HDIDSVRRFLDAAKRSGVSLPAVFGVFYYRSANRGTLEMLKGFLPVPVEQLTREFEAGAR
PEEVCARTVRALAEVGIRHFYISNLPIRRTHSALAMVGDLARI
>A0A4Y7QD24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickenella mellea|TrEMBL
MKLSEKIRHSERSRPFFTFEFFPPRTDQGFANLLARISRLASLDPLAINVTWGAGGSTKD
RSLDLAGIAQSEYGIDTVLHLTCTNMVQGSVDAALRDAKERGIHNILALRGDPPRGEEYW
IPTDPRFTHAIDLVKYIKSSPEFSDFCVGVAAYPDGHADRETDEDGEIKYLKAKVDAGAD
FIVTQLFYDVDGFLRWLSKVRETGIGVPIIPGIMPLQNYGSFLRLTKLCGTRVPVELQAA
LEPIRHDDQMIKDYGVSLATTMVKRLVSEGGIEGVHFCTLNLERSVQRVLEDLNWIGGSH
DIHNRLIAETPGSIIHAPHPESDLIITPIDASNTAKTKLETKPVKEIEEPGRGEANNEAT
WDEFPNGRFGDFKSPAYGIQDPWNPGHYVSRNEGLSTWGHPKTIEEVTGLFLSHLHGKVT
STPFSQSPLLPESLTILRQLEKMTKRGWWTVGSQPAVDGADSSDDVFGWGPRGGYVYQKG
FVEFFADKADVDMIEERVKRQGGGWVDFLAGNVDGECKTNMSDDGRNAVTWGVFPGREVA
QSTIIERDSFLAWKDEVFTIWSQWALFYPPDSKERQLLESICRERWLVSVVHHDFKKDSA
LWSFLLSEE
>A0A2E7BL71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRLIGDIYKERLRTGQPVVSIEFFPPKTPSGDTRLFDHTLPALQRLAPDFYSVTYGAGGS
TRDKTLEVVDRIQQEHQTTTMAHLTCISSSLAQIKHYLFEARQRGIRNILALRGDPPQDS
SISADTSKSFEYAFQLVSFIKQLGGFSIGTAGFPESHVACDQGKHVDWQRLKVKIEAGAD
FVLTQLFFNNDDYFIFRDYLVNTLGVEVPITPGLLPIQSTKQIKRFTALCGATLPASLLT
KLEKLGDDTTAVSEFGIEFASRQSEALIAGGAPGLHIYSLNKPDAASQILKNLSLRA
>A0A356IGG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidobacteria bacterium|TrEMBL
MRLIRDIYADRQSVDRPVLSIEFFTPKTSKGDKVLCESTLPALIRLRPDYCSVTYGAGGS
TKSKTLSLVNMIQRQFGLTTMAHLTCVESSKNDIGVVLNEAKELGIRNILALRGDPPGGS
GEFIKADDGFEYSYELVRFIKANGDFCVGTAGFPEGHIACTEGKHVDWGYLKNKVDCGAD
FVLTQLFFDNADFLQFRDYIVKKLGVTVPICPGVLPILSSKQISKFTELCGAGIPKALAA
RLESLGDDDEATTAFGIEYATKQCEELIREGVVGLHMYSLNKAHSTSAIIKNLGLS
>A0A4S2S2V1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. A1547|TrEMBL
MALGTASTRTDRARTVRDLLASGSPSYSFEFWAPKTEKGERNLWNALRRIEAVGPSFVSV
TYGAGGSTRGGTVKATQQIAADTTLTPVAHLTAVDHSIAELRNVIGQFADAGIRNMLAVR
GDPPGDPMGPWLAHPEGVHYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVD
KCRAGADYAITQMFFDPENYLRLRDSAGKAGCETPIIPEVMPVVGIKQLDRLPQLSNAVF
PAAVKERMLAVKDDPAAVRSIGIEFATEFCARLLYEGVPGLHFITLNNSTATLEIYENLG
LHQRA
>A0A1X1QX37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium bohemicum|TrEMBL
MEFGPCGGVRHDGQCEMRPGPCSFGDVVPWSGDPVEPRAPRPVRAPLVLADFSCTPFDRG
AVAATASVLAPGCDAVLVGEHQNKPDFPPTLMGSLLLDAGVTPWITLSCRDRNRVVLEQE
LRGLKAIGVDTALCVTGDGRGYDVRPEVTQTFDLDGPRLVSLAAALDMVPAVPETPTAPP
VHARPARLVEKQRAGAGVAVLNHVPSPDVVAEFTKAARSLGLVIPVIAAVAVFTDSVSAA
VLEGLPGVGLDGELIERVLGAADPVAAGIAAAVDEARTLLSIDGVDGVNISGLASASGAR
VGAEIKAEVGRRVRKEAS
>A0A0C1J3Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leisingera sp. ANG-M7|TrEMBL
MDHTLPQPYSAPPEGHVSHSRLERVLRSGRFAITAELNPPDSADPADVYEAARPLGEVAD
AINATDASGANCHMSSIGISALLTRAGYSPVYQISCRDRNRIAIQGDVLGAAAMGVSNVL
CLTGDGVGVGDQPGAKPVFDFDSLSLLRTIKTMRDERKFLSGRTIKNPPQLFLGAAENPC
IPPYDWRPERLAKKVEAGAEYIQTNYIYDVPLFEKFMARVRGLGLDKKVYILAGVGPLAS
ARAARWMRSNVPGIHVPDAVIGRMEKAEKPGQEGKKICVELIQQMREIAGVSGVHVMAYR
KEHEVSEIIRESGVLASRKR
>K0EXX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia brasiliensis ATCC 700358|TrEMBL
MLNPHKSFPARIAPAVRGVPSVVQSLRLHSRQRVPFSVEFNPPRDAAGEARLWRAVREFE
RMHPAFVSMTYGAGGSTKDRTARITGALAQETTLLPVAHLTAVGHSIAELRALVGSYADY
GIRNILVLRGDPPGDPLGEWHKHPEGVEYAEELVRIVRDLGDFNVGVASFPQLHHRSPDL
DTDTAFLAAKLRAGADYSITQMFFEVDHYLRLRDRLAAADPEQGAKPIIPELMPVTSLRT
VARAEELSGRALPEPIMARLLRAAGTGPEENRAAVREVGIELATELAQRLIDEGAPCLHF
ITLNFAKATTEVLTNLGYAVTAAPLSA
>A0A2E5FZM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonadales bacterium|TrEMBL
MREDVSQNDFSIELFPPKGPKGAARLEDALTELGALNPAFFSVTFGAGGTTRSGTLDTVK
TAMRVTGRPAAPHLSCIEGTQDSIGELLDNYKAAGVERIVALRGDLPDGMDKPGVFNYAN
ELVAFIKERHGDDFHLEVGAYPEFHPTAPSPEADIDNFIGKIRAGADSAITQYFYNADAY
FNFVDEVSARGVDVPIVPGIMPITDFDQVSRFSAMCGADIPRWVRQKMEGYGDDKASVRA
FGRELVYNLCEQLLAGGAPGLHFYALNKSQPTATLWQDLKLPTGESDAAQSGVS
>A0A5P9YP45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nonomuraea nitratireducens|TrEMBL
MSISMLARRPATVKEALASGRPTISFEFFPPKDGAATGRFWECVREIEAVRPSFVSITYG
AGGSTRDRTIDVVAAVARTATMIPVAHLTAVGHSVADLRLILERYREAGVRDVLALRGDP
PGDPQAEWVPHPRGVAHAVDLVRLIREHGDFTVGVAAFPEKHPRSPDWESEIRYFVDKCR
AGADYAITQMFFDVEDYLRLRDRVAAAGCDVKIIPEIMPVTDAAQIERFAALSGATLPEP
LASRVRAAGDPAAVRAIGVEHATMMGARLLAEGAPGLHFITLNRAGVVLDIHRALGLPAA
RP
>A0A7R9UU95|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Diacronema lutheri|TrEMBL
VRAALDAARAAGIVNVLALRGDVPAAVEAATDGVRAAPGSGALTFPHAVDLVRFIRAHYG
DAFCVGVAGYPEGHVDGESYEADLAHLAEKVAAGGEYILTQHFF
>A0A1H5EXN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas kilonensis|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLIATARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRNLLTQYKAAGIKRIVALRGDLPSGMGMASGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLRNFVRKANAGASSAITQYFFNADSYFY
FVERIRQLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSSSIQSFG
EEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLKLPR
>A0A1B3MNL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobium sp. RAC03|TrEMBL
MTLPSIHPNWDLPPKGMTDGYSLEITAKDIDALREAAPTMAAETPVAVTFLPGESLEARI
AAAKLVRSLGFEPMPHFSARRLESGDDFETYLAAVVREAGVQRCFVIAGDPPEAAGPYSD
SMALIRTGAFERAGIKAIGVGGHPEGHPNMTPDQCFAVLTEKCAEIEQRGMAPLIVTQFS
FDAAPVLSWLAELRQRGIDAPVRIGIPGPAGIKTLMRFAARCGVGASASVLTKYGISITK
LIGTAGPDKLVDALASGLGDQHGKVRLHFYPFGGLSKTVEWINDYTARH
>A0A349L0I9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Janthinobacterium sp|TrEMBL
MQTPNFSIEFYPPKTPEGAEKLRLTREKLSLLGPKYFSVTFGAGGSTQRGTLATVIEILA
AGEQAAPHLSCVGGTRESVRAILAEFQSHGIDRLVALRGDLPSGYGASGEFRYASELVEF
IRAETGFHFHIEVAAYPEVHPQAKSPQDDLQNFARKVQAGADSAITQYFYNADAYFQFVD
ETRKLGLDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTQLCERLLAGGAPGLHFYSMNQAQATTALWQRLA
>A0A0R1ETB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus zeae DSM 20178 = KCTC 3804|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNVALTPILNTLDAVKEADPDFVSVTFGANGNKPHM
GTLEVAKLIKDEFDLEPVAHLPAAQLTRAQVDAELRGFQEAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQRGDFNVVAACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYRFRERTELAGIHVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIATATKTIRNA
>A0A4R8WP19|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. MDB2-A-2|TrEMBL
MSTPTDSARTRRIPFSFELYPPKTDAAASALAKTIDHLAAAGPDFLSVTYGANGSSRRSS
LDVLSRILRTTNVEAMAHLTCVGSTHDEANRLIREFLDAGVRSFLALRGDPPAGTKEGEA
FLGDFGSAAELVQLIHRVQAEKSPYRETIIPGIPAARAVKPGHEKVRIAVAAFPNGHPRS
RSSAQDIDTLLAKQAAGANLGITQLFFHADHFLSFVQRAREAGVLFPILPGIMPVTSPAR
LRRIIELSGEQMPADLSIRLEIEPTKEGQREIGIQHAVDLASQVIAGGAPGLHLYAFNQH
ETVLEVLDGCGLLGAPAPVRTPTALPTIV
>X6KWG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacteraceae bacterium PD-2|TrEMBL
MTRPEISLEFFPPKNIEGTFRLWDSVQVLAPLAPRFVSVTYGAGGTTRDLTRDVVATIHK
HSGLRTAAHLTCVDATREETLEIAQSFAKVGVTDIVALRGDPPKGSDGFSQHPGGFANSV
ELIEALADTGDFTIRVGAYPDTHPEAANAGADIDWLKRKLDAGATEALTQFFFEADTFFR
FRDACAKAGIDQYVTPGILPIENWKGARRFAEGCGTKIPAWVIEAFEKAERDDRQDLLAT
ALCTELCSDLIEGGVDKLHFYTLNRPELTRDVCFALGVTPNQTLKNVA
>A0A1H5FBL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. 2231.1|TrEMBL
MNPALTAPPDGGTPGPHGAESQERATGLLDDFSLEMTGKDVTRLEEASDSIPPGTRINIT
FLAGEDLATRLTAARAVRRLGFVPVPHISARRLPSRAALEEFLSGLAADGTAENVFLVGG
DPARPEGPYADALALLRTGLLQEHGVRHVGISGYPEGHPAIPDPTLWSALTDKAAAIGAH
RFGGDVITQFGFDPVPVLGWLEAVRARGVHLPVRIGVPGPAGVRRLLGYATRFGVATSAS
VARKYGFSLTNLIGTTGPDRFLHALAERYDPARHGRVKVHFYTFGGLRTTAEWAARFRQE
DHAPTGRP
>A0A179I7F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cordyceps confragosa|TrEMBL
MHVKDLLAETKRSGQPSFSFEYFPPKTAQGVQNLYDRMDRMYNFGPQFIDITWGAGGRVA
ELTCEMVLQAQAVYGLETCMHLTCTDMGMDKVNDALHKAYKAGCTNILALRGDPPRAQEK
WTATEDGFQYACDLVRHIRATYGDHFDIGVAGYPEGCDDNDNEDELIEHLKYKVDLGGTF
IVTQMFYDVDNFIRWVGKVRAAGIDVPILPGIMPIATYASFLRRCKHTGCNIPQGWLDLL
EPVKNDDVAVREVGKKLVVGMCRKLMAAGIHHMHFYTMNLAQATRMVLEELSWTPSAERP
LQQALPWKPSKGFGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRLKWGEPKSLRDIANTFVRYLNQEIDSLPWSEAPLTSEADSIKPALME
LNQRGFLTINSQPAVDGVKSSHPVHGWGPANGYVYQKGYIELLVPPEIVDQVIQLVSANP
SLTYYAVTKDGNLKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGVDW
AHCFESKSPSRALVEDVMDNWYLLNIVNNDFHDNTTIFELFKELQVEGLDTPMTVKAPAD
APAAPVAEKPTAVQTEAAA
>A0A5C2HS43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodospiraceae bacterium BW-2|TrEMBL
MTQPQFSFEFFPPKSAEAKQTLQQTRQQLQQLKPAYVSVTFGAGGSTQHGTIETVSEMLA
AGLDTAPHLSCIGASRDDIAKLLQRYVEMGVTRIVALRGDMPSGMRDTGELNHANELVEF
IRQRHGQHFTIEVAAYPEFHPQAVSAEADLDYFAQKVAAGADSAITQYFYNVDAYRHFLD
SCHQRGITVPIYPGIMPVTNIKQLARFSAICGAEIPRWLRLKLESYGDDLSSLRQFGLDF
TLQLCQQLLELGAPGLHFYTMNQVGPTEYIHRHLQS
>M4BSS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyaloperonospora arabidopsidis (strain Emoy2)|TrEMBL
MGKIIESIRSAYAARADDASSTRPTVSFEFFPAKTDAGVFNLLTRVEEMGLALQPTFMTL
TWRSAFTDEALWLRIGGHIQNEFQLDVLLHLTCHLPTEDLKRILKNARAAGIRNILALRG
DPPIGAERWTPVKNGLCNAVDLIKLIREEHGDFFCIACAGYAEVHTESWNHPDLPPSNEA
RALDLKRLKDKQEAGAEFIITQFFFDVDNMIRWIADCRDAGITIPILPGYLPIQNYSSFR
KFTSWCKTRVPEQVLADLDAVKNDDAAVRRYGTQLAVETCQRLLAAGVNSLHFYTMNLAA
TVTQVLEGLQLLPARNQRELPWQSTLQRSSIEGEQVRPIFWSNRQASYIARTAAWDEFPN
GRWGDRTSPAYGELSEYYLAFKRPKLQRTELWGTPQDEQDIWNVFVRFIEGHVKQLPWCE
QALSRESAVIRENLQWLNANGFLTINSQPRVNGAPSSDSSVGWGGDNGVVFQKAYVEFFV
APEKMAHLVKVMRRDYPQLSFHALNRRGDEHRNTPLHSVTAVTWGVFPGIEIVQPTVVDS
DSFAAWKDEAFELWQTQWASAYPLGSRSYEVIQHIYDTYFLVNIVDNDYANDESDIFSIF
TRIITDAMDKEQLRARVLELETRREKMFDTLASFQSLQKEQNGQLRAVHSELANVRSENL
QLKEKVHQLQAQLALASL
>A0A7W6EYJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevundimonas mediterranea|TrEMBL
MAASSTNLAEARALLLSPLGPVARAGSNQDAVRVSFEFFPPKTDEAEANLWTAIRRLAPL
NPAFVSVTYGAGGSTRERTHRTVQRIIAETALRPAAHLTCVEASRDEVDEVIAGYKTIGV
DHIVALRGDPPGGGGIGGVYQPRADGYANATELTAAIRRIGGFDVTVGAYPEKHPESPSI
DHDIDVLKAKVDAGATRAVSQFFFDIDAFLRFRDRVRAAGVTIPLIPGVMPVSNFAGLTR
MCGACGTSIPDWLKAHFDGLDDDPETRKLLAASVAAETCARLQEEGFSDFHFYTLNRADL
VYAICRVLGVRETKAAA
>A0A4R6HS69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis|TrEMBL
MGLLEDLQKQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETSLPIMLNVSMHEQGVLQDGTP
LSEALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTRAKEFIS
VQHERTEPGLNEIAAEKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDSIRETMALAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIK
QKDEQRQNIYLH
>A0A158SIR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Macaca fascicularis|TrEMBL
MVNEARGNDSLNPCLEGSASSSSESSKDSSRCSTPGLDPERHERLRDKMRRRMESGDKWF
SLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYC
GLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
HIRSEFGDYFDLCVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
KACTDMGITCPIVPGIFPIQGYHSLRQLVKQSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
LAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKM
WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
TINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYE
EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDALELLNRPTQNEREMEAP
>A0A7W5L3W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK312|TrEMBL
MSHIDENPLGVHLPLDPLPGHSSLGRLERVLRRGEFAVTAELNPPDSANAEDVYERAAIF
EGWVDGINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGAAAMG
VCNIMCLTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDNAKFLSGRKLTSPPKVFLGA
AINPFAPPYDFRPYRLAKKIEAGAQFVQSQYCYDVPMFREYMKKVRDLGLTEKCFILVGV
GPLASAKTARWMRSNVPGVHIPDEIIKRIEGAQDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEYVAEMVHDSGVLKGRQPWKREAGRTDALVAERLHQISEGREENQQAMAEIAA
HHTPPQTH
>A0A1H3ZTV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassobacillus cyri|TrEMBL
MRLDQALQEKTLIGDGAMGTLLYSYGVDRCFEEMNLSHAKEVRNVHKAYVRAGADVIQTN
TYGANYIKLSRYGLEDHVKAINTAAVQLAKEAAGEDAYVVGTIGGIRDIQKEIPSMEELK
RSFREQLYCLLMEDIDGLIFETFYDLEELTTVLEIARQETDLPLITQVSMHEPGVMQNGM
PLMDALQLLEQKGADVVGVNCRLGPYHMIQSLEDVPLPDKAVLSAYPNASLPDYEDGRLI
YPTDPTYFRTSALDLYRQGARLIGGCCGTTPEHIAAVAKEVKGRQPITDKVVPIKHPSVP
KQADASNREDHLHDIAKERRSIIVELDPPKKLNTEKYLRGAKALKDAGVDSVTLADNSLA
SPRISNTAMATIIKQEYAINPLVHIACRDRNLIGLQSHLMGLHTLGIREVLAVTGDPTKI
GDFPGATSVYDLSSFDLIHYIKQLNEGISFSGKSLGEKTDFSVAAAFNPNVRNLNRAVGR
LEKKISYGADYFISQPVYCEKQMVEVYEATKHLTTPIYIGIMPLTSSRNAEFLHHEVPGI
KLSQEIRESMEKHSHDKELSQAEGIAIAKSLIDAALDLFNGIYLITPFLRYEMTVELTEY
IKQQTEKQERKISNGIHII
>A0A1W2DK32|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporomusa malonica|TrEMBL
MTTKRSFSEALADPAQLSVTWELVPGRGAREKAQEHFVKMAELAAKDPKINAITVTDNPG
GKSAILAYSMAIEAKRLGIDPLVHFTSKDKNRNALESELYALDRADIQNLLVMTGDYPGA
GYAGSAKPVFDLDAVHALRMITKMNEGAYTKLPATKFFAGAVVSPFKSTEAEIMAQYYKL
HKKIANGAKFIITQLGYDARKFDELRKYVDTHTLTVPLIGNIFVLSLPVAKLMNKNLIPG
CVVTDSLVAKLEEESTYSNKKELQLLRAAKLYAVLKGLKYNGVNIGGHGLSYIDVQYIIE
KGEELSVNWQEIAADDFDHPQDGGFYFFEKESATGLNTCQPVNRSQTGSSNSSLKQSLMD
VVHEVAFDHKAPLYPLNKAIAQFIDKSWLKQPFTLAEYTTKTMTNECRFCGDCAMHELGF
ICPMSQCPKQQRNGACGGSRDGWCEVYPGKQKCIFVTMYEGFKGRGKEERMKAKYMPPCN
WDLHRTSSWLNYFNDRDYNNNKE
>A0A7W5L4G2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK312|TrEMBL
MSSRSESHNAGIRISFEFFPPKSEEAEQQLWNTVEELSDWDPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLATGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVGALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKAENGADRALTQF
FFDNDAFERYHDRVRAAGIKIPVVPGIMPIQNLTQLKRFAGACGASIPSWLDERFDDLDD
NIEERAKVAADVAAEQIQDLVRRGIHEFHIYTMNRSPLVSAVLERLGLQRKVASQAGAAA
>A0A352PPP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophobacteraceae bacterium|TrEMBL
MNTTTPSKLEKIIAAGHLAVTSECGPPRDGRPGVVEHKANLIRNHVDAINVTDNQTAVVR
QCSLAACIRLKLMGLEPVLQMVTRDRNRIAIQSDLLGATSFGIHNILCLTGDHQRFGDHP
SSANVFDMDSTRLIQTVKLMRDEGRLLSGFEMQEGRPQMFIGAAENPFADPFEIRVLRLA
KKAAAGVQFIQTQCIYNMPKFKTWMQGVRDMGLHEQVAILAGLTPMKNVGMAKYMKNRVP
GIDVPDDIIKRLAGVPKEKQAEEGIQILLEQIEELRQVEGIKGFHIMAIEWEEKVPEIVE
RAGLFPRPSLN
>A0A5C1AWF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limnoglobus roseus|TrEMBL
MHMHIQDIFRDHATTFSFEFFPPKTDEASEELFKNIASLQELQPSFVSVTYGAGGSTRDR
THDLVVRIQKETDLTAVSHLTCVCHSVDEMGAILDRYAASGITNVLALGGDPPKNLANFD
RAKDGFQYANQLVEFIRNRPNVPDPRGFGIGVAGFPEGHPGCPNRLLEMDHLKRKVDAGA
DYICTQLFFNNNDFYDFRERCELAGIKVPIVVGIMPITSKAGMVRMAELALGARIPARLL
KAVSRCEDDDAVRRVGIHWATEQCRDLLDHNVRGIHFYTLNKSDATRQIYNNLGVRDSVA
LRAG
>A0A5N7X3U9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonas sp|TrEMBL
MSFPVSFEFFPTKTPEGAAKHVGVRQALYARKPEFCSVTYGAGGSTQAGTFTMVRDIQNE
GVGAASHFSCIGATHEKVRAELNELKAMGVKRIVALRGDLPSGYGLGGEFQYASDLVAFV
RQEFGDWFHIEVAAYPETHPQAKSPRSDLDAFVAKVRAGADSAITQYFYNADAYMRFVDE
VKALGLDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQAFGDDTASIRAFGLDVV
THLCEQLRSQGAPGLHFYTMNQSVATLEICDRLGL
>A0A235B1A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paludifilum halophilum|TrEMBL
MRRLLSTARYEVLPTAGIVERIEEYVAPGREITVTASTGLTLEATLSTAEQLQALGFRAV
PHLAARMIHGRPELTEIVDRLAEAAVDRIFVPAGDATPPAGGYVGAHDLLVDLSSMAAPF
RHIGVSAYPESHPIIP
>A0A1M3LP07|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Magnetospirillum sp. 64-120|TrEMBL
MSLPIATASAKPVAVSFEFFPPKTEKMQESLWECVKRLEPLDPSFVSVTYGAGGSTRERT
HETVVRIARETKLKPAAHLTCVGHSTGEVDDIARRYWDEGIRHIVALRGDAPEGSGKYQP
TPGGYAYAADLVAGLKRIADFEISVAAYPEMHPDAPSAGFDLDNLKRKIDAGATRAISQY
FFDVDVYRRFMDKVRAAGITVPVLPGILPVTNFAQVQKFSAACGASVPAWMAKLFEGLDN
DPETRKLVAATVAAEQCRALAADGVTDFHFYTLNRADLAYAISHILGVRPKAI
>A0A1Z8P0F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium TMED23|TrEMBL
MQPRIIKSRRIKKIIPKFSFELFPPKTSKLREQSMICLDQLTRYAPDFVSITYGAGGSSR
DKSKDMIKVIQQNHKLEVAPHLTCAGISKTKTLNFAKNCWDKGIRQMVALRGDPPKNTNK
FKAHPNGFKSSIDLIDGLGKIGFTNIKVGAYPELHPDSKSMGSNINWLKKKVDAGATSAI
TQFFXDAKVFLEFREKSIKAGINIPIIPGILPIENYRKTKNMAKRCGTTFPKHLNEQFAK
IKIESEEKKIALEVSTKMCDKLIKEGVQNFHFYTLNKPILTSQIIGNLGFSQITQNRGAK
NCSMI
>A0A1C9WV05|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. U41|TrEMBL
MSPPSLIDTHPNLAGPAPVALSYELFPPRSPAAAESLWTTIGELESTDPDYVSVTYGASG
SNRNTAVELINRLVQETTLRPLAHLTCVGNSPQELAEIIGELLDVGVRGILALRGDQPND
GAVPPEGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLLTRARRAGVTIPIIPGVMPLTSIRRLTRLGELTGVE
PDPALIERLAAADSDAQRARIGVGATVDLANAALDAGAPGLHLYTFNEHTAALDVLDKLA
LPRPRRSHQRTAGRRQQRTAGRRQLAS
>A0A345ZHU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lysobacter sp. TY2-98|TrEMBL
MVPVSFEFYPPKTPEQQAQFDNTVAKLKRHRPEYVSVTFGAGGSTLSHTPETIQKLRTGG
LEAVPHITCMGGSREEIRGLLKLYRALGAKRLVALRGDLPSGMVSAGELRYADELVRFIR
EETGDHFHVEVAAYPEMHPQARDSQVDLKNFIGKVRAGANGAITQYFYNADAYFRFVDDV
RRAGIDIPVVPGVMPIANFSQIRRFSELCGAEIPRWIEQRMLAYADDAESIRAFGAEVVA
QLCRRLVEGGAPSLHFYTLNLSKPTLNVLAQMR
>A0A0J6CQZ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Parabacteroides goldsteinii|TrEMBL
MKVIDLINGSKTTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKYINITSHHSEYIYKTL
PDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDETEYALIDLNFLGVYDL
LLLRGDVKTLEAGQNTDLYHEHATDLQEQVNNFNKGIAVDGSTFEANETPFSYGMACYPE
KHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVERCRAEGIDVPIIPGIKPV
VFKNQLTVLPKIFRSDIPEPFAAELRKCKNDDEVKAVGVEWCIQQCKDLIAHGVPSLHFY
TMMATDSVYKVAKEVY
>A0A2E2WI74|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micavibrio sp|TrEMBL
MIETKPTISFEFFPAKTEAGLEKLKKDAAILSGLNPTYMTVTYGAGGSTQDKTFEIVEQM
QELTGKPIASHLTYINKPKKEIYALADEIWDRGIHHLVALRGDMPEDLNWPLDPDEDYFQ
YTSHFVAALKARQDFEISVGAYPEKHPDAPSLDADIEALMKKCDAGADRAITQFFFDNKH
YYEFLEACAKVGINKPIVPGILPIHDFEKMMGFAKMCNTTVPYEIQRRFIESPPEDHTKI
AEEIFITQCRDLIENGVSHFHFYTLNKAEMLEHACRELGLNK
>A0A6V8M7A3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus curdlanolyticus|TrEMBL
MKLDLREVLRQRVLTGDGAMGTYLHHSGFPVGVSYEEYNVIHPDVIGSVHRSYYDAGARL
IETNTFSANVEKLSKYGLESAVEQINRAGVRIARTSVGSDAYVVGAVGSIRGGRRSGILL
TDVERALSQQINTLLDEDVDGILLETFFDLEEIRLALRLVRQVSALPVICQFAIEEGGGI
ADGAGLAQAFSILEAEGADVVGFNCRSGPRGLIRAIESIGENMSLPVSVFPNAGFPEYVD
GTYTYPASPDYFGEMACRFADLGVRIIGGCCGTTPDHIKAIAAALDGYVPSTLEGSALQV
ITAAPSVTISSAPEPPGAPPDAIAPSIVELVKQRHTVIVELDPPRDLDITRFMQGAAALQ
AAHADALTMADNSLAVTRMSNMALAAIVKEQVGIRPLVHIACRDRNLIGTQSHLMGLGAL
GIDHVLAVTGDPARFGDLPGATSVYDMTSFEMIRMIRQLNDGIAFSGKPLRQKASFIVGA
AFNPNVKHLDKAVARLEKKVASGAHFIMTQPVYDVELIDRIAAATRHIEVPIFVGVMPLA
SGRNAEYLHNEVPGILLSDDVRKRMAGLEGEAGRAEGIQIATELIDAIIPHFNGIYLMTP
FMLYEMTVKLTEYVWKKSGRFIVENGSG
>A0A0B5QK03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium beijerinckii|TrEMBL
MIKELLKNDILICDGAMGTYYSEVTGNDVSYCEFGNLNDKETIKRIHKEYIEAGAKLIRT
NTFSANTYDLGVSLETLMDIIKSGINLAKEVTENTSVLIGASIGPIKTDNLDEFSNEVLE
EYKYIVDCFLKNGIDIFIFETFSNYNYLKKISEYIKYKNIDSFILTQFAVKPDGFTRDGI
SAAKLIKEVRNTKYIDAFGFNCGSGPAHILEMVKKINIENEIVSVLPNAGYPEIIHERTV
YPNNPVYFAKKVSEIRSFGVSIIGGCCGTNPSYIKQLTKIINENSKVINANTKAEPKVKS
FEKKAKNTFKDKLENGEFVVAIELSAPIDTNISRIIDGAKICKENNIDLVTVPDSPMSKV
RADSTIISSKIKREIGIEAMPHVCCRDKNTNAIRSSLIGSHIENIRNILAITGDPISDAS
KVETKSVFNLNSFRLIELIESMNEEIFKEDSIYVGGALNLNVLNKEVEYNRMMKKIEKGA
KFFLTQPIYDDNAIEFLKMIKERTNVKILAGLLPVVSYRNAMFLNNELPGVTIPDKYVQM
FSENMSKEEAQEIGVKITVEIGKKLKGIADGLYFITPFNRVNMLIEIIKQINA
>A0A8I0UGU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gluconobacter sphaericus|TrEMBL
MNANLKHLFSGKLAEHPLFCHSGMPVPVLSFEVVPSRTNAMEQRLWQCVRRLEPLSPRFV
SVTYGAGGTMQARTQETVLRLKQETTLAPAAHLTCIGATREEIDDIARTYWQAGVRHLVA
LRGDAPAGTDYTQHHGGYAYASDLVAGLRRIADFEISVAAYPETHPTALSPQADLDNLKR
KIDAGASRAITQYFFEASTYLRFLDRCLAAGITAPIVPGIMPVSNYNQIVRFSALCGVTV
PTWVTHLFEGTAKNPELCRIVACVIAAEQVRALQSHGINEFHFSTLNRPDLTCAIAHILG
VRPGS
>A0A1B9BQQ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium beijerinckii|TrEMBL
MIKEILKNNILICDGAMGTYYSEVTGNDVSYCEFGNLNDKETIKRIHKEYIEAGAKLIRT
NTFSANTYDLGVSSETLMDIIKSGINLAKEATENTSVLIGASIGPIKTDNLDEFSNEVLE
EYKYIVDCFLENGIDIFIFETFSNYNYLKKISEYIKSKNIDSFILTQFAVKPDGFTRDGI
SAAKLIKEVRNTKYIDAFGFNCGSGPAHILEMVKKINIENEIVSVLPNAGYPEIIHERTV
YPNNPVYFAKKVNEIKYLGVSIIGGCCGTNPSYIKQLTKIINENSKVINVNTKAEPKVKS
FDKKAKNTFKDKLENGEFVVAIELSAPIDTDISRIIDGAKICKENNIDLVTVPDSPMSKV
RADSTIISSKIKREIGIEAMPHVCCRDKNTNAIRSSLIGSHIENIRNILAITGDPISDAS
KVETKSVFNLNSFRLIELIESMNEEIFKEDSIYVGGALNLNVLNKEVEYNRMMKKIEKGA
KFFLTQPIYDDNAIEFLKMIKERTNVKILAGLLPVVSYRNAMFLNNELPGVTIPDKYVQM
FSENMSKEEAQEIGVKITVEIGKKLKGIADGLYFITPFNRVNMLIEIIKQINA
>A0A432SYN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfurovum sp|TrEMBL
MFEKFCDVLCLEKEFITVEINPPHGASIDSIIAEIKKYNLQDKVTGFSCTDNPLAKLKMS
GVLSAIKVQQAFKKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKFSDQPE
VKGVLERDSTLLLSIIYHLNNGVDYSNKALHPKPKPIYPFAVTNAYAKDMNSLKKRMVKK
LNYGARAIITQPVYDIDNAKELLALFEEAKTLSIRDTAKEAHLVLGQFPIVRAKTANFID
DKVPGINVPKTIIDEMNLAAMDGETKEQEVGFALSKKIFDEIMQTHGKVHLMTHNRFDLC
AQLIG
>A0A1Y1XT89|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Basidiobolus meristosporus CBS 931.73|TrEMBL
MKVITKIEQATAENRPFWSFEYFPPKTQQGINNLYDRMERMYKLGPTFIDVTWGAGGSTS
DLTLELCDTAQSVYGLETTMHLTCTNMPKEQIDFALKKAKECGIQNILALRGDPPRGQEV
WTACESGFSNAVDLVRYIREQYGDYFCVSVAGYPEGHLDATSFEEDLRFLKEKVDAGADY
IVTQLFYDVELFLEWVKKCREIGIQCPILPGILPIQNYNGFKRMTTLCKTFVPQAILDEL
EPIKEDDQAVKDYGVRLAISMCRRMQEEGILGFHFYTLNLERSTRLVLEGLNFVPAQETV
RPLPWNPSLSKKRANENVRPIFWRNRVKSYIARTENWDDFPNGRWGDSRSPAYGNLGVHG
VSLKQSMKEAKQLWKSPQNLSEICQLFADYCSGKVLALPWSDQPLLPESGAITEKLVNIN
RLGYLTINSQPAVNGVESSHKVHGWGPQNGYVYQKAYLEFFVSPEALDRLVHKINQDPYI
TYYAINKQGDLRTNTQSDEPNAVTWGIFPGKQIVQPTIVEAYSFTVWKDEAFELWGEWAK
VYEPEEPTRQCIESIMDNWYLVNVVHNDYQDADAIFKIFDIEDEQQ
>A0A7G2M4M7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Culturomica sp|TrEMBL
MKITDILNREASPFASFELVPPLRGSDVHKLYESIEPLMDFNPPFLNITFHRDEIEFRPK
PDGTFEKITVTKRPGSVAIAAAIMKKFKIEVVPHLICGGASKHKLENDLIDLNFLDIQNV
VALRGDAIPGQKFFTPEPDGYRYSCELVEHIHNMNRGKYLDTTLTDTVPTNFCIGVAGYP
EKHYEAPNAETDICNLKHKVQAGADYIVTQMFFDNTRFFSFVEKCRAAGITVPIIPGLKP
ISTQKHIEMLPRTFSIDIPEELMKEIRKCKDNKEIYQVGIEWCTMQSKELLSRGAPAIHY
YTMGKADNIRKILTAVF
>A0A7Y7D250|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylocystaceae bacterium|TrEMBL
MSGLPVAAPLLQDVSVSFEFFPPKTEKMEETLWASLKRLEPLAPKFVSVTYGAGGTTRER
THNTVVGIQQETSMAAAAHLTCVGSSKAEIDEIADRYWEEGIRHIVALRGDPEEGAEGYK
PHPEGYAYAVDLVEGLKKRHDFEISVAGYPETHPDAPSAQFDIDYLKKKVDAGANRVITQ
YFFEAETFLRYRDKATAAGVNVPIVPGILPVTNFKQVLKFSDACNTKVPAWMADLFEGLD
DEPETRKLVAATVASELCRVLHVNGVNDFHFYTLNRADLTYAFCHILGVRPKGNQS
>S3TT92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii NIPH 410|TrEMBL
MSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAPLEASKS
YPDSIEKVLHFSGKARDIQDFERFLEQAKSANIQNLLLLTGDKLKEHHNGRDGQPRSRYL
ESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLGYDIEAL
KQAKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQAGHTDR
VYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWSSLWQVK
TGKEFTPEIARFSRQPTSKQLIKYRQLHVMHEAMFGSKIAKGVGRFIFKASFWENALIAK
LLLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTTLDRCEFGDRECI
HSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A0H3JXC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus (strain Mu50 / ATCC 700699)|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
>A0A2W4VV86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudanabaena frigida|TrEMBL
MIESPQPIVESPFHKFRKAIASKEFLITAEVSPPKGSAPAHMLEQTRSLKGRVHAVNITD
SSRAVMSMSPVAASVLIQQQIGIETICQIACRDRNRIALQGDLFGAAALGITNILALTGD
PVKAGDYPDARSVFDYESVRLLQLIQKLNQGLDANGKALPNQGTDFLAGAAVDPQSPSWS
GLQKRFERKINAGAQFFQSQLITDFDRLDKFVNQIANQSDKPILAGIFLIKSAKNALFLN
KFVPGVQIPEHIIDRLAKAKSPLQEGMAIAAEQIQTARQICQGVHIMAIKAEHLIPEILD
RAGVAMI
>A0A5R9LCU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Klebsiella indica|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASRDELRTIAQDYWDSGIRHIVALRGD
LPPGSGKPDMYAVDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKHKVDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAKMFE
GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPA
>A0A179UC47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomyces gilchristii (strain SLH14081)|TrEMBL
MEKISDKIAALPRNANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRSLVDHALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTYAVDLVKYIRRTHGDHFCIGVAAYPEGHSDESHPEVQDPARDVPYL
VEKTRAGADFIMTQLTYDLEAYKRFENMLRTHESGVFKDIPIITGLMPIQSYHILTRTTK
LSHARVPPNIMARVEEVKSDDESVKRIGVDILCEIVNGLKEIPCPGPRGLHFYTLNLEKA
VAFTVERCSLIPPSSEPSSDSEADLDTAVSMVHGQLNNIVRMSKRRASSINSQPHNRLIV
DRPSDGRGSSQASTTHETQTLGAGMPALNPPHRATTLQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVTPAVARRLWGYPTTKEDINTIFQRHVSGDLHIVPWSEGGT
QDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAF
VEFFCTAHDLKTILKPIFENHGHDELAWFATNAAGDFESSSPPTDDSANDYSGPVDVYLD
SNATAGGTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRVFPRGSPTEK
LLDQLKNDVWLVCVVGQKYGAGCQSREAAETEGKLLWKLLAGQATEADSTNKH
>A0A430BE78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. S-NIH.Pt15_0812|TrEMBL
MTISVDQLAEARCALESPLYADVGGDLDVSFEFFPPKSEKMETQLWDSIRTLEPLGPRFV
SVTYGAGGTTRERTHATVARIQRETSLAAAAHLTCVEATREQIIEVAEEYWAAGVRHIVA
LRGDPPQAGSRFASHPGGFENAAALVAGLRKLHPFEISVAAYPENHPDSASDAADLDNLR
AKLDAGANRAITQFFFEPETFFRYRDKVAAAGIRAEIVPGIMPVSNFASVQRMSAMCGTA
VPPWMARLFEGLDDHPAARQLVAATVAAELSRRLYAGGVKHLHFYTLNRAELAFAICHLL
GVRAKGQVGQAAA
>A0A1U7D9N5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salipiger profundus|TrEMBL
MNRPEISFEFFPPRNIEATFRLWDTVQALAPLQPRFVSVTYGAGGTTRELTREVVATLHK
HSGLRTAAHLTCVNATREETLGIARQFKEAGVTDIVALRGDPPKGESGFTPHPDGFANSV
ELIEALRNEGDFTIRVGAYPDVHPEAATDTADVDYLKRKFDAGATEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGIFPVENWKGARRFAEACGTKIPGWVIEAFDKAERDGRQDLLAT
ALCTELCSDLIDGGVDKFHFYTLNRPELTRDVCFALGVTPEVKLEHVA
>A0A417UB63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium OM04-12BH|TrEMBL
MKIPQIFEAKKKEGKPVLSFEIFPPKKEAALQNIDETLSLLCDLHPDFISVTFGAGGSTA
NNKTVEIARKIKNEYGIEPIVHLTCLHYNKEEIRSILDQLKEAGIENVLALRGDMNPNIP
VKHDFHYANELVEYIKTQGDFSISGGCYPEKHLEAPDAITDIRNLKRKVDAGVDHLVSQL
FFDNEVFYDFYEKTRIAGIDVPIDAGVMPVTNRAQIERMVTMCGATLPVKFQKILHKYEN
NKEALLDAGLAYTINQIVDLIASDVDGVHIYTMNNPAVAKRICDGIRNLV
>A0A2A8VAB5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS015802|TrEMBL
MKPLLEALRERILIADGAIGTLLYSYGVDRCFEELNLSHPNEVLKVHKEYIDAGADIIQT
NTYGANYQKLSRYGLEDSVKEINTAAVRLARKAAGDNTYILGTIGGIRAIKQNVSLEEIK
RSFREQLYCLLLEGVDGILLETYYDFEELTTVLNIAKREADIPVIAQVSLHETGVLQNGM
EIKDALGQLELLGADVVGINCRMGPFHMVNSLEEVPLPKRAFLSVYPNASLPNYEEGRFY
YSAEPDYFGDISNELRQQGARIIGGCCGTTPDHIRSVASRLKSREPVKEKVVKKKKVVQL
SASSVKGNLLHEQVREKKTIIVELDPPKHLDTKLFFQGAEALKGAGIDALTLADNPLASP
RISNDAIGSLVRSRYDLTPLVHITCRDRNLIGLQSHLMGLHTLGIHNILAITGDPAKIGD
FPGAASVYDLSSLELIELIKQNNEGISFSGKSLRERTQFSVGAAFNPNFRHLDASVKRLE
KKKKAGADYFISQPIFGKEQLVQVHEATQHLDVPIFIGIMPLISSRNAEFLHHEVPGINV
PEETRLRMREAGSDPVIARAVGMEIAKDLLDTAIDLFNGIYLITPFVRYDMSIELIHHIQ
EKTITEREVPYGHHFV
>A0A2A7H4K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus sp. AFS098217|TrEMBL
MKLLDLLSKGIVIGDGAIGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVKLAKAAVTDKNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEKVDGLLLETFYDEFELFHAVKVLRKQTDIPIIAQLALHEAGTTQNGN
DVNEILTGLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYL
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPAHIKGMKRAITNETPVTEKQIFQRPQVIH
THAKRSRTHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARLLKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLIHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRTILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIKEVYEATKHLEHPIFIGIMPLVSKRNADFLHFEVPGIT
LPDEVRQRMDGHETQEAAIEEGIRISQELIDATMKYFNGIYLITPFLKYEITENLVKYVR
EKQEVKEVINE
>A0A380H8Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus saccharolyticus|TrEMBL
MSQFLNQLQNNILVADGAIGTIFYSEGLDTCPEAYNLTHPDKVERIHRSYIDAGTDVIQT
NTYRANFEKLKAFGLEHKVKEIHKAAVKIAKRAAHKDTFILGTVGGFRGVKQEDITFSTI
QYHTELQIDTLIDEGVNALLFETYYDLDELLS
>A0A264E4B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. VTT E-133280|TrEMBL
MKPDLRSAWGNKVLVGDGAMGTYLYQKGFPVGISYEELNLTSPGVIEDVHRSYIDAGAVL
LESNTFSANFDRLSKYGLESKVEEINRAGVRIARKAAGDNGYVLGAVGSIRAGKRANLSS
TELKKYFTQQITALLEEEVDGIMLETFYDVEELHLALRTVRKHSTLPVICQFAVDESART
LDGLTLPDAFRILEADGADVIGFNCNTGPNGIKRALKAVQGNLVLPTSVYPNAGVADYVD
GEYRYGASPEYFGQMAVTFADMGCRIIGGCCGTTPEHIAEISSALKGYVPQPLPEPTLPT
VERVSLQEHFGEDEGRNGREPNLVDLVKERHTVIVELDPPRDLDIAKFMKGAEALRRAGA
DALTLADNSLAVTRMSNMALGHLVYAKTGLRPLVHIACRDRNLIGTQSHLMGFDALGIDH
VLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGISFSGKPLKQKANFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDQELIVKIAEATAHLEIPVFIGVMPLASGRN
AEFLHNEVPGIQLTDEVRNRMKGLEGEAGRAEGVAIAKELLDVATAHFNGIYLMTPFMFY
DMSAQLMEYVWEKSGRKLSPLFR
>A0A8J6SZ98|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Oculatella sp. FACHB-28|TrEMBL
MSDCPHPNPQSSTPSSRLRTAAQAKEFLITAEVMPPKGGNPAHMIEMAKLLRDRVHAVNI
TDGSRAVLRMSSLASSVVLLQQGIEPVCQMACRDRNCIALQADLMGAQALGIRNVLALTG
DPIKAGDHPTAKGVFDLESVRLLKLIDKLNQGLDFNEKPLPDGATELFAGAAIDPQCGSW
SGLQRRFERKLESGAQFFQSQLISDFDRLEKFMDQVAVSCNKPVLAGIFLLKSAKNARFI
NRNVPGVQIPDAVIDRLERATDPLQEGVAIAAEQVKLARQLCQGVHMMAVKREDLIPQIL
DLAGIAPLAVKANG
>A0A2S5LTR4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylotenera sp|TrEMBL
MSTFTTSFEFFPPKTAEGIEKLRDARARLAKFEPEFFSVTFGAGGSTRDRTMDTVLEIQR
EGYGAAPHISCISSSKEEIRALLQSYQTQGIKRLVTLRGDVPSGEVSAGDFRYAAELVEF
IRVETGGHFHIEVAAYPEFHPEARTPQADLANLKRKQDMGANSAITQYFYNADAYFRFLE
QCDDMAITMPIVPGIMPIYNITQLARFSSICGAEIPRWLKMRLEAYGDDMVSLRAFGIDV
VSELCDTLLAWGVPSLHFYTLNQAGVITNILENISADSSQL
>A0A420YHZ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coniochaeta pulveracea|TrEMBL
MHIREMIADAERTGQPSFSFEYFPPKTAQGVQNLYDRMERMYHFGPKFIDITWGAGGRIA
ELTCEMVVQAQTYFGLETCMHLTCTDMGEEKVNNALKAAYKAGCTNILALRGDPPRDKEK
WEAAEGGFRYARDLVRHIRDHYGDHFDIGVAGYPEGCDDNKDEETLLDHLKEKVDMGASF
IVTQMFYDVDNFLRWVDKVRARGITVPILPGIMPIATYASFMRRANHMQCKIPKEWMDKL
EPVKSDDVAVREIGKTLVADMCRKILAAGLPHLHFYTMNLAQSTSMVLEELDWLPSPTRP
LKQSLPWKQSLGLGRREEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEENRKKWGSPKSIKEVASLFVNYLEKKIETLPWSESPLSNEADTIRDDLIA
LNKRGFLTINSQPAVNGVKSSHPVYGWGPANGYVYQKAYIELLVHPDIFPEMIKRIEANP
DLTYYAVTKSGNFRTNAPSEGPNAVTWGVFPGKEIVQPTIVESVSFLAWKDEAFQLGKDW
ARCYEAHTPTRLLLEDMMEHWYLVNIVNNDFHQPRTIFEVLDGLTVPGLDVVPQSPEIER
AQPHTNGTAPVPAAAAV
>D0RIU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brucella sp. F5/99|TrEMBL
MGFYGLSRRPDVGQTTRVSFEFFPPKTEEMEQRLWETVTRLAPLQPDFVSVTYGAGGSTR
ERTVRTVARILKETDIKPAAHLTCVDATREDVDRVAREFAALGVNRFVALRGDPANGIGE
KYVPTPGGYQNGAELVGGLRNIADFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFENDLYERYVERVRRAGIYIPIVPGVLPVHNFKQVRNFCARSATHIPAWLAERFD
GLDNDPQTHQLVAAAIAAEQVMDLIERGVQDFHFYTMNRADLPFAICHMIGIRPKTQAAL
EVA
>R7HXF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. CAG:768|TrEMBL
MKLREIYNTDKTVISFEVFPPKENSEKLLEEIKVLKHHNPAFISLTYGAGGNENKSFELL
KQIKDTGINVMPHFTCISTTKKNIERNINKLIDLKIENILALRGDIPENKEFQKHDFNYA
SDLVEFIKHKTNLSIGVAGYPEGHIESPDLDTDINYLKDKVDKGADAIFTQLFFDNNNFY
KFIDKTEKVGINIPIIPGIMPIISKKQVEKMIKLANITVPPNVQENISKLKDKDLIEFGI
EYATSQCEDLIKNGIKGLHFYTLNKSYSTNKILNNIKE
>A0A4R6CM93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. KU 011TH|TrEMBL
MTKRTPISFEFFPPKTDAGAEKLRIVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKAQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAENLDSDIQRFIEKVQAGANAGITQFFFNPDSYFYFI
ERLEQAGINIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLQAYGDDSESIKAFGHE
VVVKLCERLIAGGAPSLHFYSMNQIEPTRQLVVDLGLN
>F8H443|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas stutzeri (strain ATCC 17588 / DSM 5190 / CCUG 11256 / JCM 5965 / LMG 11199 / NBRC 14165 / NCIMB 11358 / Stanier 221)|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKAELRELLNLYKSAGIQRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVQTPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>U1ZVS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. EGD-AK9|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARQLASYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRELLTLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VGFIREETGEHFHIEIAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDIESIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQADPSLAIWNNLKLPR
>J5L259|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pasteurella multocida subsp. multocida str. Anand1_buffalo|TrEMBL
MSYAKEIDTLNQHIADLNGKINVSFEFFPPKNEKMESILWDSIHRLKVLKPKFVSVTYGA
KFW
>A0A7Z9D7Y5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rothia aeria|TrEMBL
MTTVHPALSYELYPPRSHASCDSLLKTITELEQTNPDYVSVTYSGDAQRRQKTLALLDHL
VHETSLNPLAHLICVGHSVADLERSVRLILGLGVRGFLALRGDIPPENTRPLELPFARYL
VELIRRVEREDFAHLAAGKVSIGVAAYPHKHPESSSLLQDIEILLSKQRAGADFAITQVF
FETERYSGLVDAARLAGVQMPIIPGIMPVTSLTRLTKLCELAGLEVPRELAHRLETASEP
REMHRIGVEHALDQCRKVLDAGAPGLHFFTFNEHEAVLDVLEELDVPRYSNRFKLPLSDL
QYL
>A0A4T9WHP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tissierella creatinini|TrEMBL
MTKKTDIIFPLLFDGGMGTYYPEVSNRLLPECEMGNIFDKDTILKIHREYIDAGAKAIKT
NTFHANTISLSSDFGVVEKVIESGIKIAQEAVGDRNVLIFGDIGQIGTRETTRFDDYREI
VDVFLNNGIVDFLFETYSSMDYLIEIAQYIKSKVEDSFIIASFAIGADGQTRLGEWGENL
MKEASNCGFIDAVGFNCVSGPLRIREYLERIEIPNSTISIMPNAGYPTVINGRTFYPNNK
EYFANAVLKMLDLGADIIGGCCGTTPDYIKEIADILPEYERKERVNKGTKSIKLETPYKE
NLFRNKLENGKKPIAVEFDPPQDLNIGKYMENAKKLELAGIDAITIADCPVARARIDASL
VAYKLKNELGIEPIVHMTCRDRNINATKALLLGLNVENILNIIVVTGDPIPTAEKNEIKS
VFQFNSAKLANFVDELNKDLFTNPMNIGAALNVNARNFKAELEIAKRKEEAGVNVFYTQP
VISEAAVENIRLAKQELKAYIMGGIFPIVSYRNAMFMESELSGIHVSQNIIDLYKDKDKE
ECNKLAVDIAYDFAKKIENYVDGYYIMTPFSRVDLVLGLMDKLKH
>A0A2H0HIK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium CG18_big_fil_WC_8_21_14_2_50_41_14|TrEMBL
MERTIIQYLAEAKKPLFSFELLPPLKGHNFDSIQQAIDPLVKFDPAFINITYHQQEVVYE
NLPNNLMKKHTVRKRPGTVGISAAIKYRFGIDVVPHIICGGFTREETENALIDLQFLDIN
NVLVVRGDPQPGTRIFVPEPDGNEHALDLVKQIANLNKGIYLDADLLNTRSMNFCIGVAG
YPEKHGESPNLDSDLYFLKKKIQAGASYIVTQMFFDNQKYFDFVARCREKGITVPIIPGL
KPFTTASQLTALPKTFNVDIPVDLVKEVIKCKNNQQVRQVGIEWAIQQSIELYAAGVPVL
HYYTMGKSDNIEEIAKAVF
>A0A4Q4BVY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacteraceae bacterium|TrEMBL
MTTPRISFEFFPPQSLDASFRLWETVQALAPMNPSFVSVTYGAGGTTRTLTHEAVSTIHR
NYGLPVAAHLTCVDATQTETLAIAEAYAAAGVTEIVALRGDAPKGAQRFVPHPLGFANSV
ELVEKLARTGKFKIRVGAYPEPHPDAADSNADVTWLKRKIDAGASSAITQFFFDADTFFR
FRDACARAGITAPIIPGIVPITSWEGAKKFARRCGTSVPQKLDEAFATAARDGREDLLAL
AQCTALCDKLIQGGVEDLHFYTLNRPHLTREVVRALGILPELVLEKVA
>A0A2A3CBY8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. WSM3876|TrEMBL
MNFSQRDENPAGIHLPLDPLPGHSSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETIRIMRDNGKFLSGRKLTTPPQVFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFILC
GVGPLASAKTAKWIRSNVPGIHIPDPIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A7J8NL00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium lobatum|TrEMBL
MKVIEKIHSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIISVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRFKEDVRPIFWSNRPKSYITRTIVWDQFPHGRWGDSRNPS
YGALTDHQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSYCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGKYKC
>A0A7S1C7M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bicosoecida sp. CB-2014|TrEMBL
VDVTWVAGGRTGELTRKITAHAKKFSGMEAMMHLCLTNMRVDDLRRALLAAKADGIRNIL
ALRGDPAPGQDKWAPCEGGLAHAVDLVRFIKEEFGDHFCVGVAGYPEGHVDAESYDADVR
HLADKVAAGADFVLTQFFYDTSVFAKYVRDARALGVAVPIIPGIMPIQSYSNFDKMTKYF
GMKVPPELAAALIPIRGDDEAVKEFGIRLGMQMAEELVEAGAVGLHFYTMNLETVVKGIV
TGCGLCDASKRRYPWRQFSEEGREHESVRPIYWANRPRSYLSRTATWDEYPNGRWGDARS
PAYGEISESHFYAVAVGSVAERRVAWGEAPLTHDDVYSVFVRYIKGE
>A0A854CMD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xanthomonas oryzae pv. oryzae|TrEMBL
MISIDMPSHTRAITDAYSLEVSVKDIGALTKAAPRLLPGSSMFIPYLPGQHDAARLAAAQ
LVRSLGFEPMPHLSARRIGAPEELQAFVARLVDEAGVTRCFVIAGDPSTPKGPFADSLSL
IETGVFERSGIRTIGVAGHPEGHPIMRTAEQWDVLERKCRRIQERGMAPLIVTQFGFDAD
MVVTWVEALRARGIPHPVRVGVPGPASVAVLARYAASCGVGACASVLSNYGISIGKLFGN
AGPDRFVDRLASRLTDAHGDIRLHVFPFGGIGQSVAWMAQYRSRASSQDRMSSVHADQA
>A0A3C0CYP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MQEHSFLEEIKNSVLVGDGATGTELFARGAGQDKGIERLNLIAPELVLGLHKDYVAAGSR
VIETNTFGANRINLARYGAESEVGRIIQAGVSLARSAAGGGVYVAGSVGPLPTVEGEPIA
EQEASACFAEQISALLESGVDLLILESFTNFKDAAAALGIARSMTSLPIVAQMAFDTDGY
TADGFSADDAALRCRDAGADMVGANCGYGVTSVIAAIRRMSRLGLPMSAYMNAGFPEQVE
GRLVYLSSPGYLADRARLLVGMGVRLIGGCCGTGPDTIRALKKAVRNMDGLSPIAHVKES
LPRGAAQTVSANPLPPGRILVELDPPTSLNVEPVIAAAKTLKKAGASAITIADNPLASVR
VDTLTVSAMVQQKANIPVIPHLTGRDRNRIAVQSTIMGAHVLGIRSILCVTGDPVRMCEE
PNTSGVFDVNSVGLVRLVAAFNAGQRMGRDCQTAFSIGVALNPNVRSISGQMVKLRKKVD
AGAHFALTQPVFS
>A0A7Y3D0B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIKNSKKTIFSFEILPPLKGQNIQSIFDNIDPLMEFNPPFIDVTYHREEYVYKEV
ENGLIQKKIVRKRPGTVGICSAIQNKYQVDAVPHILCGGFDKEYTENFLIDLDFLGIDNV
LALRGDAVKSEIYFKPEKDGYQYASDLVKQIVELNKGHYLDEELQNKSKTDFCIGVAGYP
EKHAEAPSLDSDIHFLKKKIEAGATYIVTQMFFDNAKYFEFVDKCRKRGITVPIIPGLKP
IATKKQLNLIPHRFNAQIPDDLIMAIVKCENNEAVRQVGIEWAVEQCKELIKEDVPVLHF
YSMGNSSNIKAIASQLF
>A0A7J8NL29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gossypium lobatum|TrEMBL
MKVIEKIHSLQEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTAD
LTLDIANKMQNIISVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKF
VQVEGGFSCALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGNDGVATPEAYQNDLAYLKR
KVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTKI
PAEITAALEAIKDNEEAVKAYGVHLGTEMCRKILAHGIKTLHLYTLNMEKSALAILMNLG
LIEESKISRSLPWRRPANVFRFKEDVRPIFWSNRPKSYITRTIVWDQFPHGRWGDSRNPS
YGALTDHQFMRPRARDKKLQEEWATPLKSIDDIQEKFKSYCLGKLRSSPWSELDSLQPET
KIIHEQLGKINLKGFLTINSQPAVNGERSDSPSVGWGGPGGYVYQKAYLEFFCSKEKLDA
LVNKCKPLSSITYIAVNKKGNLISNIGTDVNAVTWGVFPAKEIIQPTVVDPASFMVWKDE
AFEIWSRAWAALYPEGDPSKKLLEEVQSSYYLVSLVDNDYIGSDVFAVFGDL
>A0A7Y5B7G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MTRQQFADYLSDNILIADGATGTMLALRGATLPYDAACLTAPETVATVHKEYYDAGARLI
ETNTFGANRLKLALSLGFQGDPLASEDLRNQAREINLAAVKIARQATGADALIFGAVGPV
GKPLEPLGVTRLEEARLALGEQIEWLVEAGVDGLMLESFTDQTELKIAFDEARRIAPDLP
IIASKAFIEDGESLMEGLPERFAALAASWGADAVSANCIVGPQRMLEIVRSMALGTDLPI
AALPTPGLPQLVRGEVIYDIHPDYFAKGAARLVDAGARIVGGCCGTTPDHVRAIAETLKG
AKPKPTAGEKIRQARAGRQETEIPEAEPSKVSKMLGNQRVITVELDLPRGLNVTKVMDGA
RLLKEKGVHMIDISDGARARLRMNPISISHLIQRDAGIEVMMHFACRDRNLLAIQADLLG
AHSLGLRNILAITGDPAQIGDYPSATSVFDVDAVGLTRILNRFNEGYDLAGNSIGMKTNF
TIAVAYNPLANDLKAETDRLKRKADEGAHLIYTQPIFEKAYAEIAAGAAQELELPWLIGV
LPLRNRRHAEFMHNEVPGIVIPDAIRRRMDEAPEEDALKTGIEIAQNFLTEAGDLAQGIY
LMPPAGSAKIAAEVLEPFL
>A0A2N2N8H5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium HGW-Chloroflexi-5|TrEMBL
MTDKVTLIERLKTGKPLLSDGAMGTMLHSRGITYEGCFDCLNLSHPGLVADLHREYIEAG
AQIIQTNTFGANRFKLGRHGLADNLVKINAAGVDLARRAVQASFKEILIAGDVGPLGVPL
APFGRVQVDEARAAFEEQISALSAAGVDLIIIETMTDLHEIVEAVKASKSVAPKLPVVAS
MTFTRDNRTLLGDSPAKVAKRLHEAGADVIGINCSGGPNQLLNILKQMKSALPEGLFSVM
PNAGWPEQVEGRIMYSAGPDYFGEYAVSFWQAGACVIGGCCGTTPAHIKAMAEKITATTA
VEVISKRETEKSQTDNESQEVFPPTQMAQKLRDGKFFIAVEMDPPRGLSTGKLIAGASLL
SQAGADVIDVADSPMARMRMSPWAVCSLVQRKVGIETVLHFPTRGRNLLRVQGDLLAAHA
LEVRNIFVVMGDPTSIGDYPGANDNYDLVPSGLIKLIKQGFNSGHDHAGTEIGQPTNFFV
GCALNLNPVDMESELKNLRRKLKAGADFILTQPIYNPELVTKFYEAYEREDGKLPIPLIA
GLLPLASARHAAFLQQEVPGIDIPEEVHQQMAESGAQGAKAGIRLTVELVEQIKTKVQGV
YLMPAFSRFDHAAEIIEQIRGNS
>A0A7V4SWA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Armatimonadetes bacterium|TrEMBL
MVSGSRLERLLREGKFVVCGEMSPPQGADKASILKKCEYFRGFVDAVNLTDNQTAIVRMS
SVMSSVFALEGGVEPIMQMTCRDRNRLAQQSDILGAYAAGVRNILCLTGDYQSFGNHPDA
KAVFDLDSIQLINMVSGMNAGRFLSGEEMKSPPAMFIGGAANPFGEPFEMRIIRLGKKIR
AGAHFIQTQPVFDLPRFQKWMSAVRDEGYDKQVYILAGVMPVRSVKALLYMKEEVPGVRI
ADEYIKRMESAQDPKEEGVAMCVEIMKQLMEIPGVSGIHIMPVMWESITPRLVEEAGLLP
RPEPAPLEEPAKAEVPESAS
>A0A6L3VIH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomadura montaniterrae|TrEMBL
MRPVRPDRPPTVRELLASGERSFSFEFFPPKTDKGARNLWRTIRELEPLHPTFVSVTYGA
GGGTRDTTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRFAAAGVRNVLALRGDPP
GDPMGEWVKHPEGVEYAAELVRMIRSYGDFSVGVAAFPYKHPRSPDIESDTRYFVEKCRA
GADYAITQMFFRADDYLRLRDRVAAAACETPIIPGIMPVTKYSTIERSEQLSGAPFPPEV
RARFDAVADDPEAVRRLGIEHAADLCRELLDQGAPGIHFITFNQSTATREVYGLLEAGGY
GAKGSVPPMTA
>A0A7V3ZTP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-3 bacterium|TrEMBL
MAFILIKCEKVIVADGAFGTYLYKKGIPLNKNFSLLNIENPELVKSIHREYIIAGAELIE
TNTFSANLYKIPDEDICYKANLEGAKIAKEVSENKVLVAGSIGPIGKPIYPFSEIKKEDI
KKYFYPQVKGLIDGNVDLLIVETQVLIEEAEEILKVIKEIKRDIPIILSFSFNEDKLTPF
GVSIKDVVELAEKYKVEFVGANCGVGPIPTLEIINEFLNLTKIKVSSMPNAGYPVYKKGG
FFYPSHPEHFLEYAIKMVEEGVKIIGGCCGTEPRHISLIKQNLGEISKKGKGKKILIEEK
ERKGLRVICEGNLFKEKINKNEFIISIEVYPPKGILTEKIFEKFKILKQKGIKFVNVVDL
PLARMRMSGIAFAHIVKEKFGFEPILHFTCRDRNLLSIYADLLGARALGIKNILALTGDP
LFMGDYPHATANYDLTKTGLLKLIKFLNEGKDISGRDIDVKFDFFAGTSISFYEIYDEDK
IKEKVDSGAQFFYTQPVYNKFYIEKFKEKNDFPIFAGILLCKDLKQFEYFSKEVPDIEIP
EDILKKFEDFKDDFLNIQEEILVNLIFDLKKISNGIYIISPGVKTEFIEKIIKEI
>A0A7C7J3Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTDHIDKANGTTRFSFEILPPLKGQNITSIFDGIDPLMEFNPPFIDVTYHREEYVYKE
LENGLLEKKVVRKRPGTVGICAAIQNRYHVDAIPHILCGGFSKEDTENFLIDLGFLGIDN
VMALRGDAVKSETYFKPEKDGHRYADELVGQISQLNKGLYLDEELQNNTPTDFCIGVAGY
PEKHMEAPSLDSDIHFLKEKVKKGATYIVTQMFFDNTKFFQFVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMEVVKCKDNNAVRQVGIEWCIEQSKELVAQGVPILH
YYSMGKSDNIKAIAASVF
>A0A433BCL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Curvibacter sp|TrEMBL
MSQSHVSGGALPVSFEFFPPKTPEGASKLRAVRQALYSRRPEFCSVTYGAGGSTQEGTFA
TVREILSEGCSAASHFSCIGATRASVREQLATLKSMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGHDFHIEVAAYPEVHPQARSPEADLQAYAAKVRAGADSAITQYFYNAD
AYFRFVDESCKLGLQVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQGFGDDVESI
KAFGLDVVTGLCEQLRRGGAPALHFYTMNQSVSTLALLDRLGLAADAGPAAS
>A0A0Q9P1A1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Soil763|TrEMBL
MSPPSLIDAHPHPAATAPVALSYELFPPRSPAAAESLWTTIGELETTNPDYVSVTYGASG
SNRGTAVELINRLVQETTLRPLAHLTCVGNTPQQLAGVIAELLDVGVRGILALRGDQPKD
GTEPAQGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPSRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHPGQYEQLLARARRAGVTIPIIPGVMPLTSVRRLTRLGELTGVE
PAPELLERLAAADTDAERNRIGVAATVDLANAALDAGAPGLHLYTFNEHASALDVLDRLA
LPRPGARPGPRRSAAPRGGTERRLAS
>A0A0Q9NL58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. Soil763|TrEMBL
MTSTPRPGNDAGGALPLRLEIVPTDGIVARVQSGLPPGAALTVTCLPHHGVTPTVQTAVR
LARLGYDVVPHLAARSLADRAQLAGVLRDCRAAGINEVFAVGGDAAHAAGPYETGARLLE
DIAEISGGEVAVGVAGYPEGHPQRSQLHMLDALLEKQHLAASVVTQMCFSAARINWYVEL
LRREGVSLPVWAGVAGSVPRTKLISLAAKIGVGPSLRFISRKGPLARRLMDGGNYSPRRL
VSELSAGQPSLAGVHLYTFNNLDPYALARGPQGVAAR
>A0A5C6L3T4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola dorei|TrEMBL
MRVVDLIKSTDNTAFSFEILPPLKGTGIEKLYKTVDTLREFDPKYINITTHRSEYVYKEL
GNGLYQRTRQRRRPGTVAVAAALQNKYNITTVPHILCSGFSREDTEYVLLDLQFLGITDL
LVLRGDKAKHESAFVPENNGYNHAIELEEQINDFNKGVFVDGSPIKVTGTPFSYGVACYP
EKHEESPNMEQDIYWLKKKIEAGAEYAVTQMFYDNRKYFEFVERVRKEGINVPIIPGIKP
FRKLSQLNMIPKTFKIDLPQELAGEAMKCQTDEEAESLGIEWCIHQCRELIACGVPSIHF
YTVSAVNSVKEVAKAIY
>A0A5C8F563|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brachyspira pilosicoli|TrEMBL
MNNYVENFIKKLENNNEYCFTLEVSPQAKYDLSYIEEKINNSNIQNYVDAFVVTDSPFAN
IKISSILASIQLQQKLNNNKPFIATQTMRDKNSIALQNDLIGANYFDIRMILAVTGDAIA
NGNQKQAKGVFEGNSNLLIDIIKNLNKSKSLGEFTFKEPLKPIYPFCVINSYAKNNDSLK
VRLAKKANSGVKAIFTQPIYEAERLEFLLNCIDELPLKEKPILVPGFFPVLTYKTAYFIY
YNLSGSYIPDKWLEKLKKASDKSAEEERKTAIELSAKLFEDMLKIHKKMHIMSLNNYEFA
ADLLKNI
>A0A3C1L4J9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSTQRSLIADARYEVIPMKNLESQIEFIPTGASVSVTCSPAKGQQATLDLAARIVDLGHV
TVPHLSARLAEDAAAVKRLGAFCRDHGLTEVFLVAGDAPEPVGPYDGVVSFLRDFLDTDH
GLSRIGVTAYPDGHALIEQSVVHEALHAKQALLEEAGIPGFASTQMCFDLTTWKDWAVAE
RAAGLKLPLHIGVPGVIDRTKLFTMGMRLGIGNSMRFVKKNGGVLGRLFKPGGYDPNKLI
TPLSKQAQELNIEGLHLFTFNNVQATAQWQQKMLAKLS
>A0A2D8LP46|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTDHIKKANGTTRFSFEILPPLKGQNIISIFDGIDPLMEFNPPFIDVTYHREEYVYKE
LENGLLEKKVVRKRPGTVGICAAIQNRYHVDAIPHILCGGFSKEDTENFLIDLGFLGIDN
VMALRGDAVKSETYFKPEKDGHRYADELVGQISQLNQGLYLDEELLNNTPTNFCIGVAGY
PEKHMEAPSLDSDIHFLKEKVKKGATYIVTQMFFDNIKFFQFVAKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMEVVKCKDNHAVRQVGIEWCIEQSKELVDQGVPILH
YYSMGKSDNIKAIAASVF
>A0A2N2CJK0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-18|TrEMBL
DRVISGDHKNAKPVFDLNAISLIRAVKKLEEGVDLAGNKLEGEPPKFSIGAAVSPCSDPI
GPHLIKMEKKVKAGAEFFQTQAVYEVDKFVKFMKKAKRFGVPVMAGVIVLKSVEMAKYMN
ENVAGVYIPDKIISELKKDKEKTKSGQTGIEIAARLIKELKPYCQGVHLMPLGWGDKIPK
ILKLAGL
>A0A2D5TQG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKVTEHIAQSEGKTLFSFEIIPPRKGKNIQELYNNIDPLMEFNPPFIDVTTSREEYVYIE
RDGLFDRKITRMRPGTLGICAAIKHKYNVDTVPHVLCGGFTKEETEYLLVDCHYLGINNV
MALRGDAMKHQSYFEATKGGHTYAKGLVEQMVNLNQGKYLHDVMEIDDYCDFCIGVAGYP
EKHIESPSLQTDLKRLKEKVDAGADYVVTQMFFDNQKYFNFVKAAREIGITVPIIPGIKP
LAIGKHLQLLPQVFKIDLPEDLIKAVESCKNNKEVRQVGIDWCIQQSKELIDFGVPVVHY
YSMGKSSNVKAIAKSVF
>A0A349NME9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
LEEELQNTTPTNFCIGVAGYPEKHLEAPSMDSDIYFLKKKIAKGATYVVTQMFFDNSKYF
SFVEKCRKEGITVPIIPGLKPIATKKQLNLIPHRFNVDLPDDLIMEVVKCKDNQAASQIG
IEWCIAQSKELIEKGVPVLHYYSMGKSNNIKTIASKIF
>A0A3D5GN73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MANRLNNGLSRADKPRADRAVQRRLLEGMTYELIPLKNLADQSRHLPEGATVSVTCSPAK
TVDDTLDLCAGYAKKGFTVIPHFAARMVEGEDHVDRIVQRVRDIGIRKVFCIGGDADPRG
PFTDAAGFLRSFLDRRPEIDVVGVGSYPDGHATIPDQALFDALLEKQEMVREAGLQGYMA
TQMCFDATTIAAWMERRRAAGVDLPCHLGVPGAVDRAKLLTISIRLGIGHSARYL
>A0A2E2RMD5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ahrensia sp|TrEMBL
MRHSVKRIAGAPGTGKDIRVSFEFFPPKNPQMEATLTDAINRLSPLSPEFVSVTYGAGGS
TKDTSRSTLQTVLATGNTPAAAHITCVGATREEVDSVVRDFASLGIRRFVALRGDPSGGV
GTRYQPHPDGYQNAAHLVAGLKAFGDFDISVAAYPERHPESPDLATDLDMLKRKVDNGAT
RAITQFFFDNDAYERYVERVRRAGIYVPIVPGIVPIHNFSAVRNFASKCGASIPAWLADR
FDGLDRDPHTHSLVAAAVAAEQVFDLVDRGVDDFHFYTMNRPDLVFAICRLIGIRETGEA
ARRELHAA
>A0A351EQX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MAVFGTKKYDESPEAKAHRVTLIDELTFELVPLKSLDAAVQALPAGAEVSVTCSPTKGIE
ETQRLTAELQSQGFVPIPHVSARMVRDHTHTVELAEWCRELGLRQIFIVGGDAEVPGEYP
GAVEFLADFLTTNHGIDTIGVTAYPDGHAFLSHKTLRWALHEKQRLLAEAGVNGYCSTQM
CFDPDAIAKWLRVEREMGLTLPVHLGISGVVDKAKLLTMGARLGIGDSLKYLRKNVGAVV
KMMTTISYDPNDLLLPLSSDLLDLGVTGMHVFTFNQVEATNTWRESVLSS
>A0A1G5GLD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccus tibetensis|TrEMBL
MSRPAPQISFEFFPPKTLDASFRLWETARALAPFAPDFVSVTYGAGGTTRKLTHEAVTTI
NRQFGLNVAAHLTCVEATRAETMEIVDAYAEAGIREIVALRGDAPKGAERFTPHEDGFAS
SVELIEAIAARGDMTIRVGAYPEPHPDSTGDDADIDWLKRKIDAGADSAITQFFFEADTF
FRFRDRCAAAGIDAPIIPGILPVQSWSGTKRFAATCNTSVPDWAHEAFDLAATDGPEAER
ALAARLCTDLCEALIDGGVDRLHFYTLNRPELVQEVCLALGVRPTAGIAA
>A0A2E6F983|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiaceae bacterium|TrEMBL
MSIFSLNGRIDRSTAAPLRRRLLSEARFEVIPLKNLRAQLEHLPAGAAVSVTASPNKSLE
DTWELTRDLQERGFRPVPHLASRMVESHQQLSILIGELTALNLSELFLVGGDAPSPRGPY
EDSIEVLRAILELDHTLEHIGVTAYPDGHSFIETDVLNSSLHEKQKLLKEAGVPGHASTQ
MCFDPRTIRHWLEAERASGLELPIHLGIPGAVERTKLLSIGARLGVGTSLRYLQKNTGTV
ARMVLPGGYNPNKLLSPLAGDLESMDVSGLHIFTFNQLEATVAWRDGALSALKG
>M2R3N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ceriporiopsis subvermispora (strain B)|TrEMBL
MRISKKIEAAQKEDRVWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFVDITWNAGGRTS
ELTSELVKTCQSLIGIETCMHLTCTNMPKEKVDIALREAKQNGCRNVLALRGDPPMGKDE
WEAVEGGFSHGIDLVRHIRKEYGDYFDIAVAGFPQHVTLPPEERDLEMKYLKEKIDGGAN
FIFTQMFYDVEIFIKWVRAVRAAGITVPIVPGIAPIQTFNGFMKSTVLSGTTIPQATLDA
LEPYKNNDEKVREIGTKLVADMCRRILKEDIGIRGLHFYTMNLERGTRMLLEELNLVPRV
ETVKPLPWRPSLTPNRRSESIRPIFWANRPRSYVHRTENWDEYPNGRFGDSRSPAYGELD
GYGVWIKQTKEEAVKLWDTPTTAQEIHELFKKFCLGQLKALPWSDEAPASETTVIAPQLA
KLNELGFLTINSQPAVDGARSDDRIHGWGPSNGYVYQKAYLEFFVSPQLLDALLPHIERD
VNITYYVINKRGDLRTNNHSDGPNAVTWGVFPGKEIVQPTIVEAISFMAWKDEAYELGQQ
WAKLYDPDTPTRKLITNIMDSYLLVNVVHNDYKRPEAIFEPFYKAGAEYVASTHAVVANG
NGHAH
>A0A2D5HPY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKITDHIERFKGETQFTFEILPPLKGQNISALMEVIEVLMDFKPPFIDVTYHREEHVFKK
LENGLHEKKIIRKRPGTVGICAAIQNKFNIDAVPHILCGGFNKEDTENFLIDLDFLGIDN
LVALRGDAVKSETYFKPNKDGHQHASDLVKQISNLNKGIYLDEELLNSHPTNFCIGVSGY
PEKHMEAPSLESDLHFLKKKVESGADYIVTQMFFDNKKFFEFVELARKEGIEVPIIPGLK
PLSTIKQLNLIPHRFHVDLPEILIKEIIKCKDNSSVRKVGIDWCIEQSRELKKAGVPFLH
YYSMGKSDNIKAIAEQVF
>A0A2A5GYM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium|TrEMBL
MKITDHIKNANGKTLFSFEIVPPIKGKNIQGLYDNIDPLMEFNPPFIDVTTSREEYIYIE
KDGLFDKKMTRMRPGTVGICASLKHKYDVDTVPHVLCGGFTKEETEYMLVDCQYLGIENI
MALRGDAMKDEKYFVTAKGGHSYATDLVNQIQNLNNGKYLHDDVKMDSLPGFCIGVAGYP
EKHMEAPSLQSDLKRLKEKVEAGADYVVTQMFFDNQKYFEFVDAARAMGIMVPIIPGIKP
IAVKRHLQILPQVFKIDLPQDLIDAVDVCKDNKEVRQVGIEWAIQQSKKLKEAGVPVLHY
YSMGKSDNIKAIAKALF
>A0A7X9X6T7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia antibiotica|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAALVPLKPKFVSVTFGAGGSTQQGTLDTVVDIAK
EGLEAAPHLSCVGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQARSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DARQLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWIARRLESYGDDRESIRAFGLDV
VTDLCRRLVDAKVPGLHFYTLNAAASTKTICERLGV
>A0A3B0VJE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MEGSEKSNLQKTLEAGEFTITAEICPPRGADVEHFIEKARMLKGHVVAANVTDNQRAVMR
LSSLAASAILVREGLEPVYQLTCRDRNRIAMQSDLMGAWTLGIKNVLALTGDHVNCGDHR
EAKPVFDLDVVQLVETITRANNGLSLKGRELRGGTGFFTGAVVSPEADPFDTEKIKFDKK
VRAGARFFQSQAVYDMDRFRRFFDEAEKTGAKILAGILLLKSSKMAHFLNKNVPGVMVPQ
ALIDEVDQAPDQLEKGIEIAARQVKELRGYCHGAHIMAMSQEVSVPKIIALS
>A0A3B0VGB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MKSGSNLERVLASGAFAVTGELGPPKNSDPDIVRQKARILKGNVDAVNITDCQTAIVRMS
SIGAGLIAQSEGVEPVIQMTCRDRNRIGMQSDLLAASAMGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQMLGMVRDMRDGKKFQCGEEIKGPEPRFLLGAAANPFAHPFEFRAIRLGKK
VANGADFIQTQIIYNVDKFTRFMEMVRDLGLHEKCSILAGVTPPKSLGMARYMKKFVPGM
DVTDEVIERMKGAEDKQQEGINICVDIINQVKEIKGVAGVHVMAIGWEDAVAEIVERAGL
LPRPTFAEEKEVAEPVAAPETIEVRGDADNILAEAKAEAEKIIAAARQEAELITSRAVAE
PAPVETGGPTEAVAVATDDAGEHEMNEKMRLMALESVEQGLNALKKAYGLNDDQFDALLK
FVETETILKREFETAKKTPVTPAAPATPTPASPASPTSAAAAPAAPATAAAEDSAEKAAA
EAKAREEAEKAAAEEKAKAEAKAAREAEAAAQAKIAAAAKARAEAEAAAEAKAEAREEAA
VETAQKPEPAEAAKPAPAGLAVPDLAVEKTTFAERSTKVPASSYHQAYSGSIREVVLGND
DQSVTVGGAKVLPFHLFEGDMPRKPLIAMEILDIKPDNWPPTLLQYFEDVVGNPVAWARK
CVNEYQADALNVSLIGTDPNGQNRSSTDAAKDAADVIKAVEVPIIVWGCGNIDKDTETLR
ELTSLIDDKKVCLAPLQDGNYRPLGATAMAFQHPMVAASPIDVNLAKQLNILLENLGVSL
DSVLMDPSIGALGYGIEYSYSVMERIRIAALTQQDDKLQVPIICNLGREVWKTKEVGLPS
DDLLGDQERRGIMMEAMTASCMLLAGGDVLIMRHPKAINMTKSLINGLMA
>A0A6A3JMY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phytophthora fragariae|TrEMBL
MPRVSSIHVTKQKERHEEADELAATKFVLDDSTVWTGLSTEDTRAAGESEGDQERLLQRL
HLVQGLLTFVRMLRRSRGLQAEEEDDEAKTSAQWTPEWASLKRALGLQRLKAKQDAGADF
IITQFFFDVDNMIHWIADCKDAGITILPGYLSIQNYSSFCKFTSWCKTRVPESVLAALDT
IKNDDAAVRRYGTQLAAETCQRLLAAGVNSLHFYTMNLPRP
>S6C8X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393|TrEMBL
MKINQCFKDHQVISFEVFPPRKNASNVALTPILNTLDAVKEADPDFVSVTFGSNGNKPHM
GTLEVAKLIKDEFDLEPVAHLPAAQLTRAQVDAELHGFQEAGIDNILALRGDIPKSGRVS
NDFPYACDLIEHIHQRGDFNVVAACYPEKHPESPDVVSDIRHLKEKVDAGASQLISQLFF
DNQVFYRFRERTELAGIHVPIEAGIMPVINEHQIERMATMAGVNLPPKFVAMMQHFSGNK
EAMRDAGIAYAIDQIIDLLVHGVDGIHIYTMDNPTVVKRIATATKTIRNA
>A0A6B2C1Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurococcales archaeon|TrEMBL
MKFYVEVQPSRFRDKLDEQFAVIKEVSERVHVPDAPMGYPKASSIVIAFLALAHGLRATV
HLRTTDYSYVGFLNQIYGAHLIGIDKVLLLRGDPPYRGSTVSDVSPEEGLRIIRSDERLS
AMKVGFILSLRYPIEKIRERICFNPDFVLVTHKSREKLSWLTDSYGGEKIGYLIISTPRN
EELVKKLPQREDVCRLEKLAECVEESSVYLDSLLVSCPEDIKECVYALKKIM
>A0A8J5DDY9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nymphon striatum|TrEMBL
MYTSSTVSQRVDKKVESMEIYSKVNSLNDEEFCSSSSSNASPINSRPASPDLTRSYVSLT
DKIRSRMMSGNKFFSLEFFPPRTKAGAVNLLSRLDRMGLGGPLFCDITWHSSGNPGGDQE
TSSMAIASAALNFCGLETMLHFTCCDMSVDQVQTHLDRAKCLGIRNILALRGDIPDGCEK
TSKNDFRYAVDLVRFIKEVYGDYFIICVAGYPSGHPDAISYHEDLMYLKSKVVAGADFII
TQLFFDSKKFCNFVKDCRNMEINVPYYSRSYAHSIGTLLRNIVKLSKLEVPKHIVDTLTP
IQGNDQAVQNFGIDYAVKMCHEILSSDYAPGIHFYTLNREVAACVILKQLGLWHKSPSKP
LPWGNSTNHHKRCTEDVRPIFWSSRQKSYIYRTMSWDEFPNGRWGNSASPAFGELKDYYL
FVLKNRSPKKELLDMWGHELTSEQDIWNIFYCYLTGKINKHGTLVCKMPWNEEELSPETS
LICEKLANFNSKGVLTINSQPNINGWPSTDEVVGWGVPGGYVYQKAYLEFFTSKENVVAL
KEVLREYSRVNYHIINKSGIMDYTNCLKHKPVAVTWGVFPGREIVQPTVVDSDSFKVWKS
NLSQIKYLKNEGDEAFALWTEQWGKLYPEESPSRKLIKHVTESYYLVNLVDNNYPEDSCL
WNVLDAMFEKRKQLFQY
>A0A833E4X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfurococcales archaeon|TrEMBL
MSSECPKRILNGPCGGGSEGYCEVDGRVCPWVKLFKSSKGHLPKAFTEIILDRGFKIRNY
KPQKRTPLSSLMSKIANGKLVLTYEVETGKGKDINSILTLVKELKEYFDAFNFTDNPIGV
IECDPLPIAYTVMRELNVDVIPQITCKDRNRAALTSYILSVIALGIRNIIVTTGDWPHLG
GSRYVKPVFDLDSVRLVYLVRLVSDLGVDFSGRRLNTKGKIVHVGVAVNPHFKPLELELL
KLKKKIKAGAEFAQTQPVYSYEQGERFIKALKEYKINIPIILTLTPINTEMVRLLEEKLK
IPLPSTYKSVLRKCTSWEDTLNYNLEYFTKLVSELTSLDISGFHIITFGNIVLAREIAKH
VKG
>A0A3B0RY43|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MINVQVPEPYDPLSQVPLVPPAGHYSAGKFERVLRKGHFAVTAELNPPDSADPRDVLKAA
EPLVGVADAINATDASGANCHMSSMGICSLLSRAGQGTVFQISCRDRNRIAIQGDVLGVA
AMGVGNVLCLSGDGVGVGDQPGAKAVFDFDSISLLRTLKTMRDEGVFLSGRKLTSPPNIF
LGAASNPCIQPQEWQAERLAKKVEAGADFIQTNYIFDVDVFERFMETIRNEALHKKVFIL
AGVGPLASANAARWMRTNVPGIHIPDRVIDRLEKADNPGEEGKQICIELVRKMRQIEGVA
GVHIMAYRREHMVNEIIEASGVLDDR
>A0A3R9J8T3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus mitis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLAKEKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFRYATD
LIGFIKEQASHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>Q3AGZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Synechococcus sp. (strain CC9605)|TrEMBL
MERDLSTALQRAIEAGDQVLTAEVMPPRGADPSHMLAMAASLQGRVHAVNVTDGSRAVMR
MSSLASCKLLLEAGLEPVLQMACRDRNRIALQADLLGAHALGIRNLLCLTGDPVRAGDQS
DARPVNEFESVKLLQQVDALNRGVDPVQGTLPDGATTLFAGCAADPQSRSWSGLQRRLQR
KQATGARFVQTQMVMDPQALERFQRELAGPLDLPVLAGVFLLKSAKNARFINRVVPGACI
PDALIHRLECAENPAMEGVAIAAEQVKRYLGIVRGVHLMAIKAEERIPLILDRAGLSSLP
G
>A0A3N6GKP9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ADI98-10|TrEMBL
MALGTPSTRTDHARTVRDLLATGMTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVKYAADLVRLIKESGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLERFSQLSNATV
PASLKERILAAKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A5N6WPX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus sergii|TrEMBL
MHIKEKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAAEGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLEAL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIKDLSRLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLIE
LNHRGILTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDSWYLVNIVNNDFHNTYDLFELFKDLNVRDFDVEVAADNADLK
SQENETTETAAN
>A0A259N198|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 34-62-33|TrEMBL
LNTVLQLDGEIKVPTAPHLSCVGDSKAELRELLNLYKNAGIKRIVALRGDLPSGMGMASG
ELRYANELVEFIRTETGDHFHIEVAAYPEMHPQARNFESDIANFVRKAKAGADSAITQYF
FNADSYFYFVERVQKLGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDD
SDSIRAFGEQVISEMCERLLQGGAPGLHFYSMNLAGPSLAIWNNLKLSR
>A0A1C1WF14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. S3E12|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLATYHPDFFSCTYGAGGSTRDRTINTVLQLE
SEVNIPAAPHLSCVGDSKADLRGLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISNMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A522QK04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Jatrophihabitans sp|TrEMBL
MTLTIVGETVRDKLAQGRPTFSFEFFPPKTADDDHALWQTIRELEALHPSFVSVTYGAGG
STRARTIEITERIASDTTLLPVAHFTAVNHSIAELRSLIGNLAAVGVTNMLAIRGDPPGD
PNGEWIKHPDGVEYAAQLVELMRESGDFCVGVAAFPFKHPRSATVEEDTARFVAKCRAGA
DYAITQMFFDVDDYLRLRDRVSAAGCDVPILAGLMPVTNLGVITRSEQLSGAPFPARLAA
RFAAVAHDPKAVRSMGIYESSKLAERLLDEGVPGIHFITFNRSKATREVWANLALGARV
>A0A1F3C804|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium GWA2_31_9b|TrEMBL
MKVIDKINKSKSALFTFELLPPLKGHTIQEIYDTIDPLIEFNPAYINITYHQQEVIYKNR
IDGFLEKKIIRKRPGTVAIAAAIQNKYKITVVPHMICGGFTKEETEDALIDFHFLGINNL
LVLRGDPSKGARQFIAEKGGHSHSSDLIEQIMNLNKGKYLNEDLIDAMPTDFSVGIAGYP
EKHVEAPNIDIDLEYLKLKVDKGAEYIVTQMFFENQTFYRFVDKCRKIGIHVPIIPGIKP
VSTLNDIALLPQTFHIDLPNELIKEIKKCKTNKEVRQIGVEWATNQSKELIKSGVPGIHY
YTLDQSDNIKKIAQAVF
>A0A5B0EKS5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. ANT_H12B|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKADLRGLLAQYKAAGITRIVALRGDLPSGMGMASGEMRHANDL
VEFIREETGDHFHIEVAAYPEMHPQARNFEDDLTNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQGFG
EQVITEMCDRLLQGGAPGLHFYTLNQAEASLAVWNNLKLPR
>A0A1I1KI37|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. YAB3001|TrEMBL
MKIRDILNEKEVTLSFEVFPPKTDDGYSAVEKASAEIAALKPDFMSVTYGAGGGTSKNTA
NIAADLQDKYGTPVLAHLTCVSSTKEDVKNMISIYKDKGIENIMALRGDIPKGGRVCFDY
DHATQLIYDIKSQDDSICIGGACYPEGHIECARQSEDIEHLKEKVEAGCDFLTTQMFFDN
STLYQFLYRIREKGINVPVLPGIMPITNAKQVARSVALSGSTIPQKMKIMVDRFADDPQK
MKEAGIIYACDQIIDLISNGVSHIHVYSMNKPDIAAGIMRNLATIIK
>A0A2N2XUV4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-21|TrEMBL
MKVPDILNSTKKTLVSFEILPPLKGHSIESIYKALDPLMEFKPPYINVTYHQEEAVYKKH
ASGLLEKRIIRKRPGTVAISAALQYKFGVEVVPHIICGGFTKEETENALIELNFLGIHNL
LAIRGDADKNTRMFVPEEHGHPHALGLVKQITDLNKGIYLDEEIENKTRSSFSVGVAGYP
EKHMEAPNMASDLDFLKQKIEAGAEYIVTQMFYENKHYFNFVKRCRDAGIQVPIIPGIKP
ISIANHLNIIPKTFHVEIPEALEKEIKQCANNDAVRQVGTEWAIMQSKELINAGVPVIHY
YTMGKSDNIENICKNIF
>A0A4R0F4J3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. ANC 4216|TrEMBL
MSKQIPISFEFFPTKTDAGAEKLKVVHQELQLLNPEFFSVTYGAGGSTRERTLSTLADFN
GKGTPVAPHLSCIGDSKERIAELLDLYKSQGINRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFQIEVAAYPEMHPQAENFDKDIQHFIEKANAGANAALTQFFFNPDAYFYFV
DRIQKQGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLATYGDDTASIKAFGHE
VVVKLCERLLAGGAPSLHFYTMNATDPTRQLVTDLGLA
>A0A2I0TY41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Limosa lapponica baueri|TrEMBL
MVNETHHTCSPSSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQESGDK
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLKHLKEKPPVRGLSGKRFSTKEEEFSVL
LLDKQKSSQPITSRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGN
SSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTGEESVFEVFTCYITGEPNKNGHKVT
CMPWNDDPLATETNLLKEQLEKVNRRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKD
EAFALWIEQWAKLYEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLNS
PTQQ
>A0A1M3LG21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micrococcales bacterium 73-13|TrEMBL
MTELPPVLRDPSLEMTGKDVPALLEAAPHLALGTRVNVTYLGNEDLPMRTAASAAVLEQG
FLPVPHLSARRLHSQDELEEFLAALQGVGATKSVFAVGGDPNPPFGPYEDSLQLIQTGLL
PKYGVEHVSIAGYPEGHPDISDEQLWSALTGKHLALKEAGLGSTVLTQFLFDVDAAVSWI
EQVRERGVDTLIRIGVPGPAGIKRLLAFATRFGIGANAMIVKKYGFSLTNLMGTAGPDKF
ITQLAAKLTPEHGDVKLHFYAFGGLKATAEWIERFQGKWSRR
>A0A3B1AKR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|hydrothermal vent metagenome|TrEMBL
MESQKNYPQTFSFEFFPPRTEEGAAKLKAVREKLGLLKPKYFSVTFGAGGSTQQGTLDAV
VDIQQSGFAAAPHISCIGTSKQTITELLETYKANGIKHLVALRGDIPSGAGSFSDGDFNY
ANELVAFIREQHNDDFYIEVAAYPEFHPQSLNAKADLDNFKRKVEAGADSALTQYFFNPD
AYFRFIDDCEKRNINIPIVPGIMPITNYIQLARFSDMCGAEIPRWIRKRLENFGEDKESL
KAFGEDVITDLCHQLLEAGSPGLHFYTLNQANTTTNIWKNLGL
>A0A2U3AJ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kurthia sibirica|TrEMBL
MALLEDLKTKILTADGAMGTLLYSYGIDFCYEELNIKKPEVIENIHRQYIEAGADIIQTN
TYTANAIKLARYGLEKEVEAFNRAGAKIAKKAAKAGGQYVLGTVGGVVGVRKNEATLPEI
IEALLEQATILIDEKVDGLLLETFYDYEELHTLVVALRQKTELPLIAQVSMHEPGVLVNG
MSLNDALHGLEAAGANIVGVNCRLGPYHTIQAFENVEIPQHAYLSASPNASLLDVEDGKL
VFESEADYFGKAAVLLRNEGVRLIGGCCGTTPAHIREVKKQLANLSPVEDKKVVGPKEII
IHEAEKPRYEALHNKVKRGRSIIVELDTPRHLETEKFIEGAEILQRAGVDAVTMADNSLA
SPRISNIAMGSILKYEKNVRALAHITCRDRNLIGLQSHLMGLNALGIHDILAVTGDPTKV
GDFPGATSVYDVSSMELLQLIKKLNDGISFSGKPLRKKANFSVSAAFNPNVRNVARAIPR
LEKKIAAGADYFITQPVYSKEKIIEIYEATKHLDTPIYIGIMPLTSLRNSEFLHHEVPGI
KLSEEVLERMRIATTEDPITGQTEGVQIAKELIDTAAQLFNGIYIITPFMRYEMSVELID
YIHQLDQLKRGEGIHVETSY
>A0A6U4TV69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hemiselmis andersenii|TrEMBL
MPKIVDKIIPGKPFYSFEYFPPKTPAGVSNLYERVERMGRLEPLFVDITWGAGGSTTDLT
LELSSNFQQQFCLETQMHLTCTNISKESVAEALKAAKANGIQNILCLRGDPPKGEEKWTA
VEGGFNNAIDLVKFIRAEYGDYFGISVAGYPEGHIDWYKDEPQISKDNYWKDMQYLKEKV
DAGADCIITQLFYDVDIYNQWVKDCRSVGINVPIIPGIMPINTYGGFDRMVGFCKTKVPK
AVREGLDAVKDNDEAVKEFGVQFVTDMCRRLIQEGAPGLHMYSLNLEKATIDILTNLGML
KDKSERRSLPWRARIQADGSPKAAEDVRPIYWANRPRSYMARTLHWDEYPNGRWGDNRSP
AFGDLTNYHLGEIHIVDEADRRAEWGGDLASPADVHAVFGKYVDGKQKRLPWCCALDKET
EGMRANLGALNQAGFLTINSQPRVNAAPSEDPVHGWGGPGGHVYQKAYIEFFCSPETFTK
LKGALDGHKTIRYSAVNSKGDYQSTAKGGVTAVTWGVFPDREVAQPTVVSEEAFKVWKDE
AFGLWNTQWKSLYPAGSASAGVIQQIHDTYYLVTVVDNDFVNGNIFAPFSDKFNIATN
>A0A2R6DWK4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QH_1_68_42|TrEMBL
MSLDTPTTADGARALLADPRFELMPFDSFGDQMVHLPDGATIAITTSPTLGLGATIEWTE
KAAAAGYEIVPHVAARYVEDDDHLDEVAGRLVEAGVDDIFVPGGDREEPAGEFESAHGLL
VALEDLGYEFDDVGITGYPEGHDFLSDETLQDAMAKKAPHATYITTQLCFDPDDIVTWIE
SIRERGVELPVEVGIPGVMKYQKMVGVAQKVGVGDSGRNVVTNIIRGTKDGLAARRQDGG
PRRNPNGRSTRTDRAVTVFVVSVPGSAGDGFDPTTLDLAAVEYPVPSTSDVPTARLTALL
GCTGLKANARVLGPDQAVPYHTEGSQEELFVPIAGPGAVRVAGETVPATPGTVVRVAPAT
PRSALTDGDARSRWVMFGAPPTGGPEEWDPGAVILE
>A0A6N6NUD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ellagibacter isourolithinifaciens|TrEMBL
MTTVKQLFDESRAASRPTLSFEIFPPKGDLDHRTAREVAGGLAPLGPDFISVTYSAGGGG
NKHSTNDVAEIIQSDFDTVCVAHLTCAGATASSIAASIEDLRAHNIENVLALRGDIPAGV
EPAEFRFAKDLIPTLADAGFCVGAAAYPEGHIDCIDPKVNIEHLKEKVDAGASFLVTQLF
FDNDYFYRFRERCTSARIYAPITCGIMPFLSKQQIQRMVFMCGASLPSPIIKLLARYEDD
PASLRAAGIEYACKQLVDLEEHGADGLHVYTMNHPDIARACTEAIRCAG
>A0A7W2TX36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sediminihaliea albiluteola|TrEMBL
MAKQKPRISFEYFPPKTAEGKSKLLEKTSPALLELEPDFFSVTYGAGGSTRDNTFGTVAG
LRELGADVAPHLSFGGDDEAAITELLDRYQALGVKRLVALRGDIPSGMGGLGQLVYANEL
VEFVRKHSGDYFHIEVAAYPEIHPQADSYDADVYYLKKKLDAGADSAITQYFYNVESYFY
FLDQCSAAGIDKPIYAGIMPITNFPNLARFSRNCGAEIPRWICQRIEGYGQDQESIRKFG
IEIVSQLCQTLLESGAPGIHFYTMNQLEPTRTIRNNLGL
>A0A090ZF86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus clarus|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVIQINKEAVKLAKASVNERNAILGTIGGMKHIGAVTTTNMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVKVLRKQTDIPIVAQLALHEAGTTQNGN
DVNEMVTRLLDYGANVIGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPAHIEGMKRAITNVTPVTEKKIIQRPKVIH
THEKRSRAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIAAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEVRQRLGGHETKEAAIEEGIRISQELIDTAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIQ
>A0A3R6KS36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseburia sp. AM59-24XD|TrEMBL
MKITEVLKSDKVTLSMEVFPPKTTTAAEKVNEAVRDIAALKPHFMSVTYGAAGGGTSKYT
IQIAKDIKDAYGVNSLAHLTCLSSTKETVEKQITLMKEAGIENILALRGDIPKETEFPLP
GQFHYAAELVREIKRIAPEMCIGGACYPEGHPEANSKAKDILHIKEKVDAGCEFLTTQMF
FDNSIFYNYLYRLREAGVMVPIIAGIMPITKKNQVARSIQLSGSCVPARFKSIVDWFGDE
PAKMKQAGIAYATDQIIDLIANGVKHIHVYTMNDPEVAAGIQRNLSEIIG
>A0A481R0X1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. DTU12.3|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETGDHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTQSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A1H9NGF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces qinglanensis|TrEMBL
MAIGISAPRTDRPPTVRDLLASGEQSFSFEFFAPKTAKGERTLWDALRRIEAASPTFVSV
TYGAGGSSREGTVRNTERIANETTLTPVAHLTAVSHSRAELRNVIGQYADAGIRNVLALR
GDPPGDPLGEWVKHPEGIDYASELVELIKESGDFCVGVAAFPEMHPRSTDWDSDIRHFVN
KCKAGADYAITQMFFQAEDYLRLRDRVAAAGCSTPIIPEIMPVTSVQQIERFAQLSNATL
PAGMIERLHAVQDDPAAVRSVGIEYATDLCARLLAEGVPGLHFITLNHSTATLEIHQNLG
LRERATLGLRKA
>A0A2N2YVS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium HGW-Bacteroidetes-17|TrEMBL
MKVIEHFKKAESPFFSFELLPPLKGHNIDSIYNTIDNLMEFNPLNINITYHQEETIYKKH
PGGLLERKTVRKRPGTVAISAAIKYKYPSVHVVPHIICGGFTKDATEYALIDLHFLGIKD
LLVLRGDPLKGQKYFQAEEDGHANASELVEQIINMNQGKYLDEHLENKTTTDFSIGVAGY
PEKHLEAPNMEYDLAYLKKKVDAGADYIVTQMFYDNQKYFDFVKGCRNIGINVPIIPGLK
PISTLKDISLLPKVFSIDIPDELVKELGRCKTDKEAFQVGIEWGIEQSKELKNFGVPAIH
YFTIGISDNIKAIAKEIF
>A0A3P1VMA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusobacterium nucleatum|TrEMBL
MKIADIYKSKSLTTSFEVFPPNDKVGLEQVYNCLDVLSLEKPDYISVTYGAGGNTKGRTV
EIANRIKSQNGVESVAHLTCIGAKKEEIDRVLEDLEKNNIENILALRGDYPVDRELEPGN
FNYAKDLINYIHEKKGDKFSIGAAYYVEGHRETNDLLDLFHLKEKVNAGVDFLISQIFLD
NEFFYSFRDKLEKLQINVPLVAGIMPVTNAKQIKKITSLCSCTIPKKFLKILEKYEDNPS
ALREAGLAYAIEQVVDLVASDINGIHLYTMNRPETAKKIIDATGIIRK
>A0A1H9WN45|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. NFR03|TrEMBL
MSAFPGTAGDLLPGHSSRGRLEQVLRRGEFAVTAELNPPDSADPEEVYARAAVFEGWVDG
INAVDASGANCHMSSVGICALLTRMGYAPIMQISCRDRNRIAIQGDVLGAAAMGVANILC
LTGDGVQAGDQPGAKPVFDLDCMSLLETVRIMRDHAKFLSGRKLTAPPRVFLGAAINPFA
PPFDFRPYRLAKKIEAGAQFVQSQYCFDVPMFRAYMEKVRDLGLHEHCHILVGVGPMASA
RTARWIRSNVPGVHIPDAIITRLEGAADQKKEGKQICIDIINEVKEIAGVSGIHVMAYRQ
EEYVAEIVHESGVLKGRRPWRREQDPADAGVAERLDAAREGEMQDQESLAETAAKRPH
>A0A1G3CXV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium GWC1_66_9|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMTVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKVPTAPHLSCVGDSKAELRSLLNTYQDAGIRRIVALRGDLPSGMGMASGELRHASDL
VEFIRAETGGHFHIEVAAYPEMHPQARHFEDDLRHFATKMQAGANSAITQYFFNADSYFH
FVERVRKLGVEQPIVPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDLESIQAFG
EQVVTRMCEKLLDGGAPGLHFYTLNQAEPSLAIWNNLGLPR
>A0A7U4HH64|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL P4-0081|TrEMBL
MKPDLRSAWENNVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEDVHRSYMEAGSVL
LESNTYSANYDKLSKFGLESKVAEINRAGIRIARTAAGENGYVVGAVGSIRAGKRANLSS
AELKRFFSQQIAALLEEQPDGIMLETFYDVEELHLALRTVRKLSELPVICQLAVDDSART
LDGLTLPEAFRILEQDGADVIGFNCNTGPNGIKRALGTLQGRLVLPVSIYPNAGVADYVD
GQYRYGASPEYFGQMAPVFADMGSRIIGGCCGTTPRHIAEISAALKEYTVTPLPEPDEHR
MAERISVHEHLSEDEGQGGAEPTLVDLVKERHTVIVELDPPRDLDIAKFMRGAEALRRAG
ADALTLADNSLAVTRMSNMALGHLVQARTGLRPLVHIACRDRNLIGTQSHLMGFDALGID
HVLAVTGDPARFGDLPGSSSIYDLTSFEIIRMIRQLNDGVAFSGKPLKQKAKFVIGAAFN
PNVKHLDKAVERLEKKIASGADYIMTQPVYDPELIARIAKATEHLDIPIFIGIMPLASGR
NAEYLHNEVPGIQLSPEVRSRMQGLEGEAGRAEGVLIAKELLDAATAHFNGIYLITPFMF
YDMSVQLLEYVWEKQGRRLSPLFR
>A0A143XL91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eubacteriaceae bacterium CHKCI004|TrEMBL
MKIRDYLKEHILLTDGAMGTYFDEQTGGEFVCSEEANLFQPDIIAGIHQSYIEAGAALIR
SNTFSANRKTYREIMSKHGQEADDAGFVRFVQKGYAIAREAAESAARDGKVVFAAADIGP
IYEDSESSQEEMQEEYREIVDAFLEMGADIFVLETFPDERYVLFLAEYIRGKRPDAFVIG
QFSFVPTGYGRTGFHYKTVLKKAAGSGLLDGVGLNCGIGAAHMERFLRSWLEESGMPEQV
VLTALPNCGYPQIVRGHAVYSDSVAYFGEKAANLAELGAGILGGCCGTTPEYIREIAGKL
RGDTGKEMPKIRPVRRKHVTGAAEAGAKDKRTVEENVSETKALRQNTFLQKLKKGESVIA
VELDPPFDAQMDKLVNGARLLADTPVDVITIADSPLARSRADALLTAVKIQQETGIPVMP
HLACRDRNRIAIRSGLLGAYVNDVRNVLVVTGDPVGRDERAFTKSVFDFNSIKLMEFLNS
LNGELFADDPFCYGGALNQNGARLDKIAERMKRKIDAGCQFFLTQPVYSEEELERLAFLQ
KETGAKILIGIMPLVSYRNALFIKNEMPGIHVPDEVLAQYSPDGSREEWEQTAAEISKTV
ITAGKDVGAGYYFMTPFHRVSLIKRIMETCVPE
>A0A857EUM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia canariae|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVSLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTTIFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A1F7PH67|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Rokubacteria bacterium RIFCSPLOWO2_12_FULL_71_19|TrEMBL
MAAPFVARLAERPLLGDGAMGTMLYSRGVSLDACFDVLNVNEPKLVQAIHAEYIAAGADC
IQTNTFGANRFKLGVHGLAPRVGEINLCGVKLARDVRESMGRDVFVLGSVGPLGKYLAPL
GAVEPDEAGAAFHEQAEGLLAGGVDGFVVETFSDLTEQRLAVEAIRSLCDLPIVATAAFT
DESVTFLGRSPVEVVRALRALPVEAVGANCSVGSSVLYDVLEQMLPEAGGLPVAIQPNAG
LPSRVGERLMYLSSPAYMADYAARMIAAGARMVGGCCGTTPQHIRAMREAVDRHAPARPA
ARVARPVARVETGAVAALCPAAAPTRLARGLDAGEFLVTVELDPPRGHNIEKLVQGAKLL
KERGVEILDINDGSLGRVRMSVLPTAMLVREATGLDINMHFTCRDRNLMGIQADLLGAHA
MDIRNILAMTGDPPRTGDYVNATAVFDVDAIGLIRILAGMNRGLDATGTSIGEPTAFCVG
AALNPAAEEPGREMERFLHKVEAGARWVQTQPVYDLEVLDRFFAGTPPPVPVIVGVLPLH
SWRHAEFLHNEVPGITIPEGARARLREAGDRALRVGIAMAQELVGQIRGRYAGAYLMPSF
GRFEVVAEVLEALR
>A0A1T5DQF4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium nematocida|TrEMBL
MKIIDHIKQADGKTLFSFELLPPAKGKGIQSIFNTMDELMEFNPPFIDVTYHREDYLYKE
HANGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARRGDADFIPTPGGHAYATDLLQQVKDMNGGHYLHEDVESSEQTDFCIGVAGY
PEKHFESPNFNTDFKWLKKKVEMGAEFIVTQMFYNIEKYKEFVLKCRDNGIHVPIIPGLK
PLTSKKQLIALPKIFHLDIPEELSDAVDACKTNADVHQVSQEWMVNMCRELIDFGAPVLH
FYTMSSPGPTKRIVEQLA
>A0A1N6DCP7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halodesulfovibrio marinisediminis DSM 17456|TrEMBL
MKIIDAIQSQSKPFYSLEFFPPRERKQWDSFFSTVDRLKALNPLFASVTYGAGGSTQDNT
LEITSRMKHDAGIEPMAHLTCVGASKEKINGFINKLREADVHNVLALRGDSPADEKFSWD
DQEFRYASDLVNLVSTEHPDFGISVAGYPAAHPESPTFADDLHYTRVKIDAGSDFVVSQL
FFDVREYFDFVSRLRSNGINKPVIPGILPIQSLGSIRRILSLCGANIPGQLYLSLEEANE
RGGDEAVKEAGLKFAVNQIRQLIDGGAPGIHLYTLNKADMCLELADRVKL
>A0A0F0GS50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharothrix sp. ST-888|TrEMBL
QAVEGIAEQTTLRAVAHLTAVGHSDAELRSSIGRYADVGIRDVLALRGGPPGDPVGPWTR
HGQGFRHAAELVQLVKECGEFSGGVAAFAELHPRSPEWDSEIRHFVAKCRA
>A0A2R7YZ48|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides currus|TrEMBL
MDLRRSIIEGRGEVLLFALTPPRQSAPAERVREIAEVTAQRLEPLGLDGLILYDIDDESD
RNAEERPFPFLPTMDPVDYLAHHLEDWPIPVVVYRAVGKYAEPELESWLRSAAPDRTLSV
FVGASSGTKEVATSIQRAQALRAEVRPDLLLGGVAIPERHARRGDEHLRMIEKQVAGCSF
FVTQVVYDVNAAKDLVSDYRYECLARGLTPVPVVFTLSVCGSTKTLEFLRWLGVDVPRWI
ENDLTHAEDTLAASLDHALGVARELMSYCRRQGLPFGMNVESVSIRRAEIEASVELARQL
RDELDRPD
>A0A1E5LAB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfuribacillus stibiiarsenatis|TrEMBL
MNTFSLRDKLRAGTFVVTVELEPPKGADPDPTLTKAKKLYGTVDAVNIADSPMATMRMSP
IALSHILQKDVNMEAIFHLTCRDRNLLGLQSELLGAAALGVRNILTLTGDSPKQGDHPDA
SGIFDVNSVGLAKIAKTLNEGKDLSGKDLNKPSDFFIGAVANPGADDLDDEIRKVKEKIA
AGVEFFQTQPVFDIETVLTFEKRLAEENITAKILYGILPLKSFKVATYLNDKVPGIRISR
EIMDRVEAGGQVAGVAIAKELYHELRKLSIAGVHIFPIGDLNMVHTILDIE
>J3HBV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. YR343|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRAIARDYWDSGIRHIVALRGD
LPPGSGKPEMYGSDLVELLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMSAMFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAMGA
>A0A1W2CTF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfocicer vacuolatum DSM 3385|TrEMBL
MSMNTPSKLEKVFKSGHIAVTSECGPPRGSDPEAVTSKGAMIKDHVDAVNITDNQTAMTR
MSSLAACIHLKQMGLEPILQMVTRDRNRVALQSDILGAASFDINNVLCLSGDHQSFGDCA
QGQNVHDLDSMQLVQTVRHMRDEGKFLGGDDIKRPPNMFVGAAANPFADPFEIRVPRLAK
KIACGAEFIQTQCIYNIAKFEEWMRRVRERGLHEKVFIMAGMTPMKSAPMAKFMKNRVPG
MDVPDEIIDRLAGVEKKKQAQEGIDICVEHIQRLKEVEGIAGFHVMAIEWEEKVPEIVER
SGLYPRPEV
>D4XP94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter haemolyticus ATCC 19194|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLKVVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKVRIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIKRFVEKVQAGANAGITQFFFNPDAYFYFI
ERLEKAGVNIPIAPGIMPITNASNLIRFADGTGAEIPRWIRKQLSAYGDDSASIKAFGHE
VILKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A2R7YW18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides currus|TrEMBL
MTRGHGRSMRELIESGEKSFSFEFFPPKDEAGEERLWRAITELEPYRPTFVSVTYGAGGS
SRDTTVRITGRIARETSLTPVAHLTCVGHSRAELADVLDAYRDAGVAHILALRGDPPEGP
RAAWVGTEDGLEYASDLVAFIKEHYDAAVGVAAFPEGHVDAESLEADALVLKAKQDAGAE
FAVTEMVLRASDYFGLVERARALGVDMPIIPGIMPILNLGSMNRMVELSGREMPDEVRSR
IEPLAEDPAGLRAEGIRISTELCDALLAGGAPGLHFYTLNFSRATREIFEGLQITV
>A0A269TXC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. alain-838|TrEMBL
MALGTASTRTDRARTVRDILAAGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWVPHPQGLTYAAELVELIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVGAAGCDTPVIPEIMPVTSVKMLERLPKLSNASI
PAELKERILAAKDDPAAVRSIGIDFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A1A9RZ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eikenella sp. NML03-A-027|TrEMBL
MCGAEIPRWLRLKLQSYADDTASIKALGLDVVTEMCGRLLRHGAPACISTPSTRPDCLPP
SASVWATNPPFFK
>A0A1B3M1A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenophaga sp. RAC07|TrEMBL
MGLPVSFEFFPPKTPEGVEKLRAVRQQLYPLKPEFCSVTYGAGGSTQEGTFNTVRDILAE
SVPAASHFSCIGATKTSVREQLATLKAMGVKRLVALRGDLPSGYGAGGEFHYASDLVAFI
RSETGDDFHIEVAAYPEVHPQAKSPESDLQAYVTKVRAGAHSAITQYFYNSDAYFRFVDD
AYKLGADVPVVPGIMPITSSTQLMRFSDASGAEIPRWIRLRLQAFGDDTASIKAFGLDVV
TDLCDQLRNGGVPALHFYTMNQSVATLEIANRLQLS
>A0A4Q1AMB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halarcobacter ebronensis|TrEMBL
MLTDKIREKQKGILLYGITPPKINHSDEEIKEIAKKHIERISNLDVDGLVLYDIQDESDR
TDEKRPFPFIKTLDPCRYSHDYLQELKIPRIVYRAVGNYTSQTFTKWLEFTKQNQVHSVF
VGAASHEQKNPLSLKEAYQLKREVNDNLCLGGITIPERHTKKGDEHLRIFSKIDESCEYF
ITQCIYDLEAAKIFLTDYAKYAKENNYEMVPIILTLTPCGSTKTLEFMKWLGINIPNYLE
EELKESGNILQDSVKLSKDIFKELYQFGTKKGIPIGCNIESVAIRKAEIEASVELLNEIK
EIMKEN
>A0A7M1T7D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cruoricaptor ignavus|TrEMBL
MKITEHIKKANGKTLFSVEVVPPTKGESIDDLYRNIDPLMEFQPPFIDVTTSREEFVYLE
KHGGLMERRITRMRPGTLGICAAIMYKYGVDTVPHVLCGGFTREETEYLLVDCLYLGIEN
VMALRGDARKGESHFAPTDGGNANAGELVRQIDDVGHGKFLTDEGRAWENSKFCIGVAGY
PEKHIESPSLKYDLEKLKQKVDEGADYVVTQMFFDNQKYFAFVDAARNIGITVPIIPGIK
PVATKNHLSILPKTFKIDLPEDLIKAMDTAKDNAAVREIGIEWAVAQCRELLDFGVPVLH
FYSMGKSSNITKIAEQVF
>A0A417Q895|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium OM08-11AC|TrEMBL
MKIRDILNKDTATISFEVFPPKKSTDFGNVEAAALGIAALQPAYMSVTYGAGGSTKGHTI
ALAREIQKQYNVPTVAHLTCVCADRSSIGAALTEMQAAGIENILALRGDIPKDFDGEVFT
NFTHASDLVRFIKENGDFCVGGACYPEVHPDSANKNADIRGLKAKVDAGCEYLTTQMFFD
NNIFFNFMYRVREAGITVPIVPGIMPITRGVQVRNAVKLSGCNVPERFKNIVDRFGDNPE
AMKQAGIAYATDQIIDLLANGVKHIHVYSMNKPDVAAGIQRNISEILKA
>A0A087E1A6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium thermacidophilum subsp. thermacidophilum|TrEMBL
MHQPMFSIEVFPPKRNAPVGTIYDTLDGLQGLNPDFISVTYGTGKSSDRTATARIANTIR
KEYDIPVVAHLTAQYTTREQVDEALDMFKQAGVSAVLALRGDPVPDREPAGAFEHASDLV
AYIREHDPDMTIFGACYPECHPQASDLDEDISNLKIKVDAGASHLISQLFYDNADFYHFL
DKARAAGIDVPIEAGIMPVTNAKQIRRMVRMCLSRVPLPLEALLDKWGDDPKTLKQAGVI
YASNQIADLVAHGVDGVHLYSMNKPAVTRQIWHNVEDLFSPGQTGTDFA
>A0A482ZYN0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bathymodiolus heckerae thiotrophic gill symbiont|TrEMBL
MKISFEFFPPRTEQGRQALAQVRQELITIHPEYFSVTFGAGGTTQEATLETVLDIQKNNA
IPAAPHLSCVDSKKENIIKLLNQYKTAGINRIVALRGDIPSGVRDIGDFHYANELVEFIK
SQYNDHFHIKVAAYPEMHPQAKNIHTDLAHFANKVGAGADSAITQYFYNADAYFRFVDEV
QKLGIDIPITPGIMPITNYTQLLRFSTMCGAEIPKWILERLKLYENDLDSLSAFGTEVVS
NLCQTLKAQGVDSFHFYSMNRVQPSLKIAKHIND
>A0A267MH27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaeromicrobium sediminis|TrEMBL
MKIKNLFNQKRPVISFEIFPPKKSSSIDTIYKTIDGLAELKPDYISVTYGAGGSGEENKT
LEIASIVKNKYNIEALAHLTCISSTKDEIDSVLRELKENNIENILALRGDLPNDPNFKFP
DPLHYRYGSDLVKHIKKNGEFSIGGACYPEGHIENDNMDNDIENLIRKINYGTDFLITQL
FFENNNFYKFHEDLVKKGVNIPIQAGIMPVTNKKQVERIVSLCGSYIPPKFMKIMNKYEH
NKEALMEAGICYATEQIIDLLSSGIDGIHIYTMNKPEIAHRITKNIGCVVKALNEKAV
>A0A228K541|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. AU27893|TrEMBL
MKPIELSFEFFPPKTAEGVEKLRATRAQLLPLKPKFVSCTFGAGGSTQQGTLDTVLDMQK
DGLEAAPHLSCIGSSRDSLRAILDQYRSYGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFHIEVAGYPEYHPQARSPKADLENFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVEVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRESIRAFGADV
VTSLCQRLVDAGVPGLHFYTLNTAAATRTICERLVM
>A0A2K8XL30|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lacinutrix sp. Bg11-31|TrEMBL
MKVTDHIKKANGNTQFSFEILPPLKGQNIQSIFDNIDPLMEFKPPFIDVTYHREEYVYKD
LGDGLLKKQVVKKRPGTVGICAALQNKYNVDAIPHILCGGFSKENTENFLIDLDFLDIDN
VVALRGDAVKTETYFTPEKEGHHYASELVSQISELNNAVYLDDELQNCSATNFCIGVGAY
PEKHMEAPSLESDIHFLKKKINNGAEYIVTQMFFDNNKYFQFVDKCRKEGITVPIIPGLK
PISTRKQLNIIPHRFNVDLPEALIKEVIKCKDNKQVRQVGIEWCVQQSKELEKAGIPFLH
YYSMGKSDNIKAIAQAVF
>A0A2M7SV04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium CG_4_10_14_0_8_um_filter_46_9|TrEMBL
MKAGTNLEKVLESGAFAVTAEAGPAKGAVTSVIERKGEMLKPCCDAVNVTDNQSAVVRMS
SWSSCVLLKRLGLDPVMQIVVRDRNRLAIQSDVLGAVAMGIQNILCLSGDHQAIGNHPDA
KGVYDIDSIQLIQMLKGMRDEKKFQCGEEISGEVPIFIGAAANPFAAPFEYRVLRLAKKV
KAGADFIQTQAIFDVAKFAKWMEMVRDRGLDKQTHILAGLVPIKSVGMARYMKDYVSGVY
VPDEVVTRLEGAKNAKEEGIKICLETIEQLKEIQGVHGIHIMAVAWEEMVPHIVEQAKLL
PRPVV
>J8TI80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomyces kudriavzevii (strain ATCC MYA-4449 / AS 2.2408 / CBS 8840 / NBRC 1802 / NCYC 2889)|TrEMBL
MSIRDLYHERASPFISLEFFPPKTDLGTRNLMERMHRMSALDPLFITVTWGAGGTTAEKT
LALASLAQQTLSIPVCMHLTCTNTDKTIIDDALDRCYAAGVRNILALRGDPPIGEDWLDS
QSNESPFKYAVDLVRYIKQRHGDKFCVGVAAYPEGHCEGEAEGNEQDPSKDLVYLKEKVV
AGADFVITQLFYDVEKFLTFETLFREQISQDLPLFPGLMPINSYLLFHRAAKLSHASIPP
SILNRFPPEIQSDDNAVKSIGVDILIELVQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQ
SFVLSHIVNESSEEEGEDETGGEIRSIENVPIEDADGDIVLDDSNEDTAANRKRRRHSSL
DSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSR
SPAYGEIDGYGPSIKVSKNRALELWGTPRTIGDLKDIFIKYLEGSTDAIPWSDLGLSAET
ALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWEA
TLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSQVKQTTIIEEESFKA
WRDEAFSIWSEWAKLFSRNTPANILLRQVHRDYCLVSIVHHDFKETDELWEMLLD
>A0A3M4TDT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas amygdali pv. ulmi|TrEMBL
MFVSISRSASMSQERRFSFEFFPTKTDAGHEKLLTVARQLATYNPDFFSCTYGAGGSTRD
RTLNTVLQLENEIKVPAAPHLSCVGDSKDDLRNLLAQYKDAGIKRIVALRGDLPSGMGMA
SGELRHANDLVSFIRQESGSHFHIEVAAYPEMHPQARNFEDDLKHFVNKANAGADSAITQ
YFFNADSYFNFVERVEKMGVSIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAFG
DDVQSIQAFGEEVITQMCERLLQGGAPGLHFYTLNQAEPSLAVWNNLQLPR
>A0A2N2TF21|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium HGW-Betaproteobacteria-16|TrEMBL
MSLPISLEFFPTKTPEGAEKLRAVRQQLYALKPEFCSVTFGAGGSTQDGTLQAVTEIMSE
GCPAAPHLSCIGQSRESIRERLAAYRSAGIRRIVALRGDLPSGYGVGGEFRYASDLVAFV
RAETGDHFHIEVAAYPETHPQAKSPLADLDAFAAKVKAGANSGITQYFFNSDAYFRYVDD
LHKLGVDVPVVPGIMPIASSTQLMRFSDACGAEIPRWIRMRLQAFGDDTASIKAFGLDVV
TDLCDQLRNAGVPGLHFYTMNQSVATMEIVRRLALSPPSEPS
>A0A381QQ91|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKISDKIKEYKKQKKVFYSFEYFPPKTDFGMDNLYSRIDRMSSLSPAYIDITWGAGGSTA
ERTLDMSKTIQKYFGLDVMMHLTCTNMSIKLIDEVLSEAKKSNISNILALRGDPAEGSNE
WRKENQAFNYGVDLVHYIRKNFGDTFFLAVGAYPETHQEQSDPDLDITYLKEKVDAGVDI
IVTQLFYDIDKFLLFRDKCLSKGIDIPIIPGIMPIHNYSRFRKFTQFCKVNIPENILKKL
EPIRNDDASVINFGIEQGADMCEKLVKEGVPGLHFYTLNLEHSVKEILNSIGLISDNKAN
RELPWRQSSDEIRKSSEDVRPIFWSNRPISYLTRTENWDDFPNGRWGDISSPTFGELNQY
HAIRAGSKSSEIRDKRKKIWGQPQSIKDISNVFMSFCKGDINTLPWCETKLAIESKQISN
ELIKLNESGYFTINSQPNVNGAPSDDAHFGWGAEGGRVYQKAYLEFFTSKENLDRLITKI
KKNNNISYQAVNLSDDLISNVKKDSVNVVTWGVFPGEKIKQPTIVDTRSFMIWKNEAFSL
WMNDWASIYEKDSISYSLLRNIYENYYLVNIVDNDFIKSNMIKQIIK
>A0A381Z5R0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MINKEYKLVNFSLEYFPPGDQDGLKNLSNQARVMSAYLPLYMSITHSAKGAELNETMHTV
QILKEQLSVEISPHMTCSSYSKAEIIKMAEDYLSLGVESVVALRGHLIEDATIGELRYDN
SPDFINALSKKFDFRISISGYPEGHPEKKDDASDLKYLRKKCDAGADEIITQWFFSNDHL
LQFRDQCDATGINIPIVPGILPISDIKKVKNFAKACGSTIPKELEEAFLKIDGDMEATEE
LGIHYAIQQIENLHKEGIDNFHLYTLNRSEMTKQIIEYFVLSINMDDITSEKMAS
>A0A381Q2P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MDGAMGTELYASGVFVNVSYDGLNLETPDVVETVHRNYVNAGAEVIETNTFGANPVKLSS
YGLADRTEEINHAAVGLARRSAQGRTLVVGAIGPLGIRIEPLGPTSREEAQEFYKRQVDG
LVEGGVDGFVLETFSDLNEMEQAFKAVRSRSPLPVICQVTVGDDACTSYGTSPEDVATEV
ASWGASVIGLNCSVGPAVMLEAVERMAEVTDLPLSAQPNAGLPRAVGDRKIYLASPKYMA
QYARRMIEAGARFVGGCCGTSPEHIRSIRALVGGVRPPSTRARPGSHAESHDTPIQPEVP
LGERSVWGRQIAEGTFVTSVEVTPPKGWNAEILLGQCRRIQAAEANTVNVLDHPHAHTRM
SALPAAMLIEREVEIETIVHYPCRDRNMTRMISDLLGAAAAGLHNLLLVTGRPPAMGPYP
DSTASLDIDSIGLTNVVHGLNRGVDPGGNAIGVPTRFVIGVRVSQVAVDQDREAGRLNWK
VDAGADFVITRPVFDAERLHSFLEHVPELSVPIIASLRPLTSLREAEFLHNEIPGIQIPD
RVLARIANAEAHGEDAARAEGISIAMEAFAAVRDSIAGVHIHVADGNLDGALELLSEIRD
SA
>A0A382ID61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
SGIRRIVALRGDLPPGVEKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLN
LKRKAEAGATEAITQFFFDTSVYLRFRDRAAAAGVDLDIVPGILPVTNYQTLVKFAGFTN
VHVPGWLHKMFDGLDADDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAIC
HMLGVRSGA
>A0A7G9SUG7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermomonas carbonis|TrEMBL
MLPISFEFYPPKTDEQRAQLDRSVQKLKAHAPQFMSVTFGAGGSTLSHTPETVQRLRSEH
GVAGVPHLTCVGGNREEIRSLLKLYRALGCDRIVALRGDTPSGMVRSGDLRYANELVELI
RAEHGDHFAIEVAAYPETHPQAEDAMADMRNFKRKVDAGADSAITQYFYNTDAYFRFVDD
ARALGIDIPIIPGIMPISNFTQLRRFSEACGAEIPRWIAQRMRGYGDDADSIREFASDFI
AKLCERLIAGGAPGLHFYTLNLSRPSAAILQRLG
>A0A7V9E9N4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioidaceae bacterium|TrEMBL
MSTSAPLRDALDRPGPSISFEFFPPKDDAGERTLWTSIRDLEPLRPAFVSVTYGAGGSTR
DRTVRITGRIASETTLRPVGHLTCVGQTCDELRTTIGQYATAGVSDVLALRGDPPGGVGT
RWQQHPGGLANATELVRLVRRLGSFCVGVAAFTRGHREAPSLEADARVLAAKAAAGAEFA
VTQFFFRAEEYFALVERAAAHGCDVPVLPGIMPVTSLGQVTTMARLSGFEVPPEVMARLQ
PLADNPAALRMEGALIATELCGELLAGGAPRLHFYTLNRSTATRQVFADLGVGVPA
>A0A382GBA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MIRSISFEFFPPKTPKFEAKLWQSIEQLAPIEPKFVSVTYGAGGSTRTATHKIVKNIIND
TELNAAAHLTCVAATKEEVDSVIDDYKSIGVNHIVALRGDMPDMGLFKAHPDGYSSSVDL
VEAIKQHGCFEITVSAYPEKHPESSSFEADINLLKAKIDAGADQAITQFAFDIDAYLIFR
DKLVADGINIPVIPGIMPTTNFKGVQSMAEKCGTSIPEWLSAKYIGLEDDFERRQEISIK
VAVDQCRKLISEGFDQLHFYTLNQHKVISEVCNILGLGAASELGKDLTGLSKREIS
>A0A892ZLB0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paralysiella testudinis|TrEMBL
MNQTALSFEFFPTRTEEGRRKQAITRKQLSQYQPAFFSCTYGAGGTTREGTLQTITDIMS
EGIAAAPHLACVGATRQEMIDILSTYREMGIRHVVALRGDVPSGVGFGGQGLRYANELVA
LIREEFGSWFHIEVAAYPEFHPQARSAEDDLNHFVRKCQAGADSAITQYFFNIDSYFWFV
DEVQSRGVNIPIVPGIMPIASFSKLARFSETCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTQMCERLLANGAPSLHFYTLNQAGLVSTICQRLGY
>A0A7H9BCS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leuconostoc gelidum subsp. gasicomitatum|TrEMBL
MTKISKIYYTKSAPVLSFEIFPPKKETGIELLYRTLDEVNPQKLGVDYISVTYGAGGLGD
NTKTCNLAQYIQTHLGVTALHHLTGVNQTPESLRDILAKVEQANIENILALRGDLGDKTY
VNVNYPYAKDLIYGIKQLRDFNVGAAIYPEGYTGNPITGISIAGTKEKIASGADFLISQF
FFDNDMYYNMQERLKNNYIKVPVSAGVMPIISKTQIERVTHMIGSPLPTELVNIVHKYED
NSEDLKKAGIEYALKQIQELLDHGVDGIHLYAMNQPSVLKSMLPIISQEIKTKHFFENNI
SDHG
>A0A6A6DLW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zopfia rhizophila CBS 207.26|TrEMBL
MHISQKLAQSRTEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDVTWGAGGRLS
HLTCEMVKVAQSVYGLETCMHLTCTDMEKSKIDEALKEAYRAGCTNILALRGDPPREKEK
WEATKGGFRYARDLVKYIRDRYGNHFDIGVAGYPEGCEDNDNVDILIDHLKEKVDAGATF
IVTQMFYDTDIFLDWVNKVRAKSIDIPIIPGIMPIHTHAAFLRRANWTKCKIPDHWTKAL
EPIKNDDVEVREIGKGLVAEMCRKLIDAGILHLHFYTMNLAQATRMVLEELNLLPDLESP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDARSPAFGELDS
YGIGLKGTNEQNIKLWGTPTSVKDISNLFVRYMSGNLDSLPWSEAPISKEAEIIQQDLID
LNRRGFLTINSQPAVDGAKSSHPVYGWGPRNGYVYQKAYLEVLISPELIAEVITRIEHDQ
EMTYYAVNKDGDLKTNSPGDGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQEW
ANCHSSVSLSRYVIEDIMDTWYLVNIVHNDFHVAHGIFPLFNGLQVQDMEKPLHQNGTLN
GHAERDENSEKSTLNGAIEALKSATAAVGNNPKLSI
>A0A1E5TMC1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus equorum|TrEMBL
MSQLIDKLKNNILVADGAIGTILYSEGLDTCPEAYNLTHPEKVAHIHRSYIEAGADIIQT
NTYGANFEKLKDFGLEHKVKEIHQSAVKIAKEAAKDDTFILGTVGGFRGVKQEDLGLSAI
QYHTEIQVDTLVESGVDGLLFETYYDLEELTNIIKATKRKHNIPIIAQLTALNTNYLRDG
TEINTALQQVAASGADIVGLNCHHGPHHMQQSFSHIELPEGAYLSCYPNASLLDIENSQF
KYSDNAEYFGNVAQKLINEGVRVIGGCCGTTPEHIEFIKSSIDNLKPVTQKNVIPITKYT
STSSKSKQSQNLTSKVKQRPTIIVELDTPKHLDTDTFFRNIKKLDDANIDAVTLADNSLA
TVRISNVAAASIIKQQYDIEPLVHITCRDRNLIGLQSHLLGLSLLDINEILTITGDPSKI
GNLPGATNVYDVNSKGLTEIASRFNQGINTDGDALKTKTNFNIAGAFDPNVRKLDGAVKR
LEKKLESGMHYFITQPVYSTEKIKEVYEATKHLDVPFFIGIMPVTSYNNALFLHNEVPGI
KLSEEVLEQFEAVKDDKEKSKELSLKLSKELIDTVHEYFNGLYLITPFQKADYTLELAAY
SKSITSTKQEAIL
>A0A382A0B4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MTNEIIRLIKNYLNDFTIETTPNIYNKYQGFGNLLEKNHTIYVTYLPDENFKNVIDTTKK
LKLEGFDVVPHLPARTMTSKSQLEKYLGNLSEISGCNKILLIGGGSKQNGDISSSLEVLQ
TDYLSKYNYKEVGVAGHPEGSPDISKEELDKAIIEKNNFAKNADFKMYLATQFFFEANSL
IEWEKHIQTIGNNLEIHAGIPGPASLKTLIAYAKSCGISNSLQFLSKQAFNILKLASTKT
PDKLIYDLAYYKNSSNHSALKKLHFYAFGGIKITSDWLNLLKKSEFTYNANNEFEILTN
>A0A382EP90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MKISEKIAKFEAQGKTFFSFEFFPPKTDFGRDNLYSRIDRMASLHPAFIDVTWGAGGSTA
DKTLDMCQTIYKYFGLEVMMHLTCTNMPVSSIKKILIDAKKHNLSNILALRGDPPEGSHN
WEQHADGFRYGIDLVRYIRKEFGDDFFLGVGGYPDGHYEQSDIDIDIKFLKEKVDAGADI
VVTQLFYDVDKFLLFRDKCVKSGIKVPIIPGIMPINNYARFLKFTQFCKVSIPKSVSKQL
ESIKVDDSSVINYGIDQSSEMGKKLIEEGVPGLHFYTLNLEHSVSEILRSLDLVSSKGII
KELPWRQSTLDDRKTNEDVRPIYWSNRPVSYLTRTENWDDFPNGRWGDITSPTFGELNQY
HAIRAGSKSDKIKARRKKIWGEPKSINDIKDVFISFCNGEINSLPWCEIPLAQESKQISD
DLLNLNKMGFFTINSQPKINGLPSEDPVVGWGGAGGRVYQKAYLEFFTSKDKLNALLKSI
KLTDYISYQAINIDGNLITNLSENSVMAVTWGV
>A0A8H7J090|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ascochyta lentis|TrEMBL
MHISEKLARSRAEGKPTFSFEFFPPKTAQGVQNLYDRMDRMHGFGPQFIDITWGAGGRHS
KLTTEMVKVAQTVYGLETLMHLTCTDMERSKLDDALNDAYQAGCTNILALRGDPPREREK
WEATEGGFQYAKDLVKYIKDRYGNHFDIGVAAYSEGCDDNDDIDQLIDHLKEKIDAGATF
VVTQMFYDIDIFLDWVKKVRAKGIDVPIVPGIMPIHTHAAFLRRANWTRCKVPSTWTEAL
EPIKNDDVQVRQAGSELVADMCRRLIDAGILHLHFYTMNLAQATRMVLEELELLPDVESP
LEKPLPWRPSLGLNRRDENVRPIFWRNRNRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGVGLKGTNEQNIKLWGSPTSVQDISDLFVRYMQGDLGSLPWSEQAITEEANTIQKDLID
LNQRGFLTINSQPAVNGAKSSDPTFGWGPRNGYVYQKSYLEVLVSPEYISEIITRIERDP
EFTYYAVNKDGDLKTNAPSEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQDW
ANCHASASPARYVIGELIDTWYLLNIVHNDFHVTSGIFPLFDGLKVEGMGKKFETGITAD
ESTNGHTDTNGTNGTTNGNKPDIPQQDPKEAKDENSLLATAKAAAVEVTNGIKNLAVSN
>A0A381U5A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|marine metagenome|TrEMBL
MESTGSGSDHLSAMLQNSNRFLTTVEIETSRGILMGIDARKTMDSAQSLAEFDRVDFVSL
TDNPGGNPHIRPEVLGQELLSQGREVMINISCKDYNRNSVESRLWALDSQGFSNVLALSG
DYPVGGFEGQAQPVFDIDSVALIEMMARMNDGLSSKTFGSSSSEHRLEKTKFFPGCVVSP
FKKLEGELMTQYFKLALKVRTGAKFAVTQIGYDSRKASELHHYVESNGINIPLIGSVFIL
TAPAGRFFNRWGVPGVCVSDELRDIANRQAKSKDRGRLFFSELAAKQIAILKGIGYRGVY
ISGRPSPDRVQKILELVDSYSQDDWREFAKEINFSQSDEFYYYEADENPGISSANINKNY
ISSRSRLAKAKSRVGVPLQYRIGKFVHDRVFTEGSSGFKIGRVIYRQIEKNKQLSDAAHF
TEQMSKVPMYHCRDCGDCSLPDIAYLCPESQCVKNQRNGPCGGTKAGQCEILDKEC
>A0A662DLX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Aerophobetes bacterium|TrEMBL
MKLTELFNKGKFVVTSEIGPPKGTNIEPVLKEAEELKGKVDAINVTDLQSSVMRLGSLAV
CKLLKERGLEPVFQLTCRDRNRLALQSDLLSAYVLGVENVLCLTGDHNVLGDDPESKPVF
DLDSVNLIRAAKTLMEGKDLVGNKLDGSPDFCLGAVANPGADPLEPQIIKMELKAEAGAQ
FFQTQAVYDVKKFEEFIRKVEHIKVPVMVGIVLLKSAGMAKFMNANVSGVFVPDNLIKIM
AAAPKEERPKKSIQIAASLIKELKGMCQGVHLMPLGWDRYVPDVLEKSGLI
>A0A290Q3W3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nibricoccus aquaticus|TrEMBL
MQPDRSIVSLFAQNRPLRSIEFFPPKDDAGVAALRATAAALQRISPDFVSVTYGAGGSTR
ERTAQVCAFLKSDFGFTVMPHLTCVGHTRDELHTLADQIHDNGFRNIMTLRGDPPKGADT
FIPTTDGLRYASELAALLKTRHPDFCLGVAGYPEKHPEAASLEADIDNVKRKIDAGGDFV
TTQLFFDNAVYLRFVEKCHARGITVPIVPGIMPVLSLKQIQRFTQMCGATLPAKLITRLE
AAGENTDAVESVGLDWALTQIRELLVQGAPGYHLYILNRAKSALALAAGLAA
>A0A2D7IH71|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MLSNYKNLKVSFEFFPPKSEKMEQSLWHTFKRLEPLKPQFVSVTYGAMGSTRKRTHELVS
KIKKESKIQPAAHLTCVNSTKEELIDIADTYWNEGIKHIVALRGDRVLENGNSINDQLNY
ATDLIKILKSRNDFEITVSAYPEGHPESDTTEKDYDVLKRKIDLGATRGISQFFLDTDIY
LKFLENIRKRNINIPIIPGILPVTNCKKTIEFSNSMNCNIPNWLKNMFIGLDSDPETRKL
VAATIAAEQCMRLLKEGIKEFHFYTLNRADLTFAICHILGIRTLQD
>A0A1E5UBC2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cloacibacterium normanense|TrEMBL
MKVTEHIQNANGKTLFSFEILPPLKGQNIQSIFDAIDPLMEFNPAFIDVTYHREEYEYVE
REDGLLEKRVVKKRPGTVGICAAIQNKYGVDAVPHILCGGFSKEDTENFLIDIDFLGIHN
VVALRGDAVKTETYFKPEKNGHAFAKDLVEQIVKMNHGTYLDESLENSACTDFNIGVAGY
PEKHMEAASLEQDIYHLKKKVEAGADYIVTQMFFDNQKYYDFIEKCRTSGINVPIIPGLK
PITTKSQLSMIPHRFKVDLPNDLVIAIAKAKDNKEVKEIGINWCIQQSKDLMKNGAPVLH
YYSMGKSEVVKRIASEVFKD
>A0A2D7Q635|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MNNINVSFEFFPPXNXVSIDSLWSNIRRXEPLQPKFISVTYGAGGSTRENTHKLVKEIKK
ETSLTPAAHLTCXXTSVKEIERIADDYWXNNIXHXVALRGDXPKVKQGXNELXFATDLXK
VLKKKFDFEITVSAYPEKHPDSRSIEQEYDILKMKIDLGAXKAITQFFFDINSYFDFLDG
AIKRGISIPIIPGILPVTNCKRTMEFAKKMNCKVPRSXVEMFKGLDSDIETRXLVATTIV
YDXCMKLISSGIKDFXFYTLNRADLSFAICHILGIXILKDDX
>T2G8U4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Megalodesulfovibrio gigas (strain ATCC 19364 / DSM 1382 / NCIMB 9332 / VKM B-1759)|TrEMBL
MRIIELMANGQFVSLEFFPPKEKEKWPEFYEEVEQLKSLRPLFVSVTYGAGGSTRDRTLE
LVTTLKGGHGLVPMAHLTCVGAEEQALAGYLDALAAAGVQNILALRGDPPKGEANFIPSD
ARFRYASDLVRFIKARHPNMCVGVAGYPEKHPEAPSMDTDLAALKIKVDAGADFIVTQLF
FDNALYFAYVDQLRAMGIALPVLPGVLPVLSMASVQRMAAMCGASITPEYQAELQAADAL
DQAARERGEPAAAVPDAGIAHAREQVLGLLRGGAPGVHLYTLNKAAACLRIVKDADVCPL
TGSC
>A0A520V0A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Dadabacteria bacterium|TrEMBL
MIKKKLLKSIEIIPPRYKIDNQLLRNLTKYQDNFDFLDIACSPMANLRISAITFAHNLII
KGIKKEKLIINFSTRDKNTLALQSEILGTYAMGINRLLIVKGDKISYGNSLKSKEVFEVS
TNELIKIINNLNNGHDYSSNMLKFKTKFNIGSTLNIDSSYSIVKKTIQKRIKSGSNFFIT
QPLYSEKDFVLLSKLSKNKNYQILAGILPIKNKKTFVNLINKINGISKVNELFDLLSGAN
EKDFADISTKYLLNLLEKYKSELDGVHIMTSGDIRLASKIANKI
>A0A1U7IX53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nostoc calcicola FACHB-389|TrEMBL
MHHTHSPTAFRRAVQTGEFLITAEVAPPKGGDPAHMIKMAATLKGRVHAVNITDGSRAVL
RMSSLMASVILLQNGVEPICQVACRDRNRIGLQADLMGAHALGIHNILALTGDPVKAGDH
ADAKAVFDLEAVRLLQTIRKLNQGVDCNDKPLTDGALDLFAGAAVDPQCKSWSGLQSRFE
RKIEAGAQFFQSQLITDFERLEKFMDTIATGYKKPILAGIFLLKSAKNAQFINKCVPGVD
IPQHIIDRLAKAKDPLEEGMKIAAEQVQIARQLCQGVHMMAVKREDLIAPILDLAGIAQV
NQLVSR
>A0A2M7M3L6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium (Candidatus Ratteibacteria) CG_4_10_14_3_um_filter_41_18|TrEMBL
MSKLSEALEGKKFVVTSEIGPPKGTNIEKCLEDAELLRDKVSAINVTDIQSAVMRIGSLA
ICHLLAEKGLEPVFQMVCRDRNRLALQSDLLSAWVLGIKNVLCLTGDYTSLGDHPETKPV
FDLDSVQLLKTVATLNQGHDIAGHELDGTPNFFAGAVVTPGCDPLEPQIIKMKKKIDAGA
KFFQTQSVFEPKKFESFMNDVEKFHVPVMAGIVVLKSAGMAKFMNENVAGVFVPEEIVKE
MAETKKEDRRKKAVEIAARIIREIKPICQGAHIMPLGWDALVPEIINQAELS
>A0A4Q2Y0M1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiaceae bacterium|TrEMBL
LTPNRLVEMDHLKAKIDAGADYICTQLFFDNHDFYDFRERCSLAGIHVPIIAGIMPITTT
NGMKRMAELSGGSVFPARLLKNLQRAGSDPEAIRRVGLHYATEQCADLLNNKVAGIHFYT
LNQSTATREIYASLGLKDSRALMPSVA
>A0A424Y204|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfonatronovibrio sp. MSAO_Bac4|TrEMBL
MKISELISGSNPFFSLEFFPPREKTAWPGFFEQVEKLKQINPLFVSVTYGAGGSTQDYTL
EIVTRMKKELALEPMAHLTCVGASKEKIQNFLNGLDDAKVQNVLALRGDPPQGEKKFIPD
SEEFQYASDLIGFIRSAYPDLCMGVAAYPEGHVEAPGLDEDLAFLKKKLDLGSDFAITQL
FFDNSLYFNFVEKARSLGIHKPLIPGILPVTSLNIIKKSISLSGASLPPGFMETLEEAEK
RGGAEEVKKVGTDLAIAQVRGLLEGGAPGVHLYTLNKAETCLEIVKNFEHYFAQA
>A0A2E2PGK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rickettsiales bacterium|TrEMBL
MLLNNKDLRVSFEFFPPKDKXMEDSXWKNLKRLEPLNPEFVSVTYGAGGSTRDRTHELVK
KIKNETXLEPAAHLTCMGSTLNEIKEIAEXYWNDGIKHIVALRGDIPKDNVSQCEDLNFA
TDLIKTLKKNNNFDITVSAYPEGHPDSKTKEQDFDVLKKKIDLGATKAITQFFFDNSVYI
DFLDKARKRNINIPIIPGILPVTNCKKTINFSNSMNCKIPLWLKKMFIGLDSDPETRKLV
AATIAAXQCKNXAEQGIEQFHFYTLNRAXLSFAICHILGKRSLKD
>A0A2B4S656|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stylophora pistillata|TrEMBL
MGFGRQDTAPAMEFLQCVNNDRGSKSNTPSVPSSPLTLIEKINQKIAAKEKFFSLEFFPP
RTPNGAVNLIAKFDRISMGCPLFCDVTWHPAGDPGGDKETSSMTIASAALNYCGLETMLH
ISCANTVKATVTKHLMKAKTLGIRNILALRGDPPNGEEWQALDDGLAYGTDMVKHVRQEF
GDTFTICAAGYPNGHPDCPTYEEDLQHLKEKVDAGSDFIITQLFFENKTFFKFVKDCRDI
GITVPIIPGIMPIQGYASLRHLVKLSRLEVPQWIVDAIEPIKDNDEAIRKYGVQLGIQMA
RELLESDDVPGLHFYTLNREVATKEILTALGLWCQDPAASRPLPWKPSANKKRVCEDVRP
IFWASRPKSYMYRTSDWDEYPNGRWGNSSSPAFNDLRDHHLFYLRSKSKKEDLLKMWGGE
LTCVEDVFEVFRCYISGENNRNGVQVKSLPWNDDTIAPETSLIKEKLEFLNSHGFLTINS
QPHVNAKPSSDPLVGWGGSGGYIYQKAYLEFFTCKENVDILLEVLKDYPQVNYHFVNREG
SVNVTNSDKLSPIAVTWGVFPGKEIYQPTVVDPISFESWKDEAFDLWDQRWGRLYKEDSQ
SRQVIDDIYNNYYLVNLVDNDFIKGNCLWETLEKTVELREGGAQRMAAEA
>A0A512QEM6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus kloosii|TrEMBL
MTQQLLDKLKNNILVADGAMGTILYSEGLDTCPEAYNLSHPERVERIHRTYIEAGADVIQ
TNTYGANFEKLKAFGLEHKVKDIHQAAVKIAKKAASQDTYILGTVGGFRGLRQEELSLSA
ILYHTEIQVDTLIEEGVDGLLFETYYDLEELTNIIQATRNKYDIPIIAQLTASNTNYLRD
GSKINDALQQVIDSGADVVGLNCHHGPHHMQQTFSHIELPEHAYLSCYPNASLLDLNNSE
FKYSDNAEYFGKVAEKLINEGVRLIGGCCGTTPEHIHYIKSSIKDLTPIHNKKVVPITKQ
STATKSTSAKENLTAKVKRDATIIVELDTPKHLDTDKFFENIQKLDNAEIDAVTLADNSL
ATVRISNVAAASIIKQNYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILTITGDPSK
VGNLPGAMNVFDVNSKGLTEIAKRFNQGINTDGDALKKKTNFNIAGAFDPNVRKLDGAIR
RLEKKIDSGMDYFITQPVYSKEKIKTVYEATKHLGVPFFIGIMPITSYNNALFLHNEVPG
IKLSEDILTRFEAVKDDRDKTRELSIEICKELIDTVHEYFNGLYLITPFQRADLSLELAA
YSKSITSNSQEAIL
>A0A842NE15|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|archaeon|TrEMBL
MEKITDVLKKKGFTISVELVPPRNGIHQEKILSDLEKVKDKIDFISVTKGAGGSMRGGTI
PLTYFSKEIGLNPVAHFVCRERTKYELENELMDLHYFGIKNILALRGDAPADHKEEVWDG
DYIYAYLLAKQISNMNYGKYLPMTNSTDEYRDGFKTDFCIVVAGHPEDPIEEEARHMKCK
VDAGADAIITQMIFSFEEYKEYVDGLKAASINLPVIAGIRPFMSFKQLESAENFFKIKIC
DELKNGLKNAGTKEAEFDFGVNYAADMIKKIQEYGGAGVHLFVLNDFDLVAEVIKRV
>R5VZH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus eutactus CAG:665|TrEMBL
MNILESLRDKLLVADGAFGTCYAGMYGERGTVAPELANMRHPERVLEIHKEYVKAGAGII
RTNTFAANTASLDADMDYVISNVRAAVKLAKQAVAETGAPGIDRKKAYVAGDIGPIPADA
GLTLNERVSQYKLLGEAMQDMGVDIIWFETFPEFNVLEPVVKQLKARKDTPVMVSFCVNQ
FGYSNCGFSARALLSQAAANSDVDCVGLNCGVGPYHMLQLLKKLDIDCGKPVSIMPNAGY
PKFTQSRLVFNDNKEGFIDKIQDIAALGADIIGGCCGTNPEYIRQIKESVKKGDIVKAAK
VHVEKQQFDNAPKDNFLKGRLKSGKAAVKNAGGHKLIAVELAPPVDVNDQKLLDAAHILK
QSHVDVVTFPDSPSGRTRADSILMAEKVHKETGLRVMPHLCCRDKNAIAIRGSVLGAQLN
GIKDFLVITGDPVPVMFRQTTRSVFNFDSVGMMKLLQTMNEEVFIGDKITYGGAINQNRI
NTKFEIDRIKRKLEAGAEFFLSQPVFSREQAQILRDMKAETGATILVGIMPLVSRRNALF
MKNEMTGIEIPDEIIERYGENATRQEGEDCGIQIAREILDYTADFADGYYFSFPFNRVHM
LAHIVD
>A0A2N6QD51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus pettenkoferi|TrEMBL
MDKLLHKLQTQVLVGDGAMGTILFTEGLDTCPEAYNLTHPEKIEAIHRSYIEAGADVIQT
NTYGANFEKLKAFGLEHKVKHIHQAAVAIAQRAAQPETIILGTVGGFRSVTQEDLSLSTI
LYHTELQIETLIQSGVDALLFETYYDLEELTAVVKLAREMTDRPIIAQLTASNTHYLKDS
TEINRAIQHVVKCGANIVGLNCHHGPHHMQQSFSHIDLPQDAYLSCYPNASLLDIENQEI
RYSDNAAYFGKMAQKLINEGVRLIGGCCGTTPEHVRYIKQAVKDLSPVTRKNVIPIKKRE
TNQAIPTHKKNLTSIVKQRPSIIVELDTPKHLDTSTFFDNVQQLDQLGIDAITLADNSLA
TVRISNIAAASIIKQQYNIEPLVHIACRDRNLIGLQSHLLGLSLLDITEILTITGDPARI
GNLPGATNVYDVNSRGLTEMALRFNQGINTDGAELKQRTHFNIAGAFDPNVRRLDHAVKR
AEQKIKHGTHYFITQPVYSSDKIQEIYEATKHLETPFYIGIMPITSYNNALFLHNEVPGI
TLSDDILEQFEAVKDDAAQTKALSLKLSKALIETVHRYFNGLYLITPFQRVDLTIELAQY
SQTITSTKQEALL
>A0A839U7U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phyllobacterium trifolii|TrEMBL
MSIHEFKAKSQQDQMTKIAASIEVAARQAIESQDLPGLFPTGTRVYITDMGTDSVDTLTA
AAKRIHELGYKPVPHFASRRLSTKAALETRIRRAAQEAGVTDVLVIGGGLERQAGEFSST
MEVLETGFFDKYGITEMGVAGHPEGSPEFSEAVAIEALRLKKDFGERTGAKLRVVTQFGF
DADRFIRYSESLRQHGVDLPVHLGVAGPAKITTLIKYAAMCGVGNSISFLKKNALSLTAL
ATSHSPEGVVGPIEQHVLVNPTSAIKQIHIFPFGGLKKSSEWLVDRGSWNVDTQYANAAT
N
>I9KDH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. QA3|TrEMBL
MDHGRPVGGFELICEIEPPTRPDLTHARHQIGVLGPVTDAFLIPDNHLGRATVSSIAVAH
EVQTMGGRSIACVNARDRNLLGLRRDLLTAAAYGVEEFLFVHGDKPTVGNRSGELTVRAM
MDAARAAGADPVFADRPAFRVGAAAGLRPLPAWKRTADFLFVQVCYSVDALLRWRDAHPV
ELPVYAGVMVLASVGMARRLAESIPDIDIPDALVEAVERDRAAGVEAACAQVLHLRDSGA
FAGVHLVPVSRYRQVAARLEDLL
>A0A525PQE4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfitobacter sp. SK025|TrEMBL
MTTPAVSFEVFPPKSVDASFRLWDTAQALAPLGPRFFSVTYGAGGSTRDLTHDSAHVLRR
TSGLPVAAHLTCVGASKAETLEVANSFAEIGVTDIVALRGDPENGASVFTPHPDGFADSC
ELIEALAATGKFTLRVGAYPEPHPESPDQAQNVEWLKRKFDAGADEAITQFFFETETFL
>A0A1E4V469|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. 21C1|TrEMBL
MSQERRYSFEFFPTKTEAGHEKLMNVARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEIKVPAAPHLSCVGDSKAELRELLGLYKNAGIKRIVALRGDLPSGMGMASGELRYANEL
VSFIREETADHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGADSAITQYFFNADSYFY
FVERVQRMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDTDSIQAYG
EQVITQMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A147IRN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sanguinis|TrEMBL
MTNTILTRAEAALAHEEPLFADVGGDIAVSFEFFPPKTEKMDTQLWDAIRTLEPLDPRFV
SVTYGAGGSTRERTHATVARIQRETTLAAAAHLTCVEATREEIDQVAHEYWAAGVRHIVA
LRGDPPAEGARFVSHPGGYENAADLVAGLKKLHPFEISVAAYPECHPESTDKAADLDNLK
RKIDAGATRAITQFFFSPEAYFRFRDDAAAAGITAEILPGILPVSNVAQTRKFAALCGAS
IPDWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKGFHFYTLNRAELAYAISHLL
GVRGKKAEAVAAA
>A0A6M0FLX0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO1I7|TrEMBL
MNRFRNAVKSGEFLVTAEVAPPKGADPTHMIEMASTLKGRVHAVNVTDGSRAVLRMSSLA
ASIILKNNGIEPICQVACRDRNRIGLQADLMGASALGLNNILALTGDPVKAGDHKDARSV
FDMESVRLLQMIAKLNQGIDWNEKALPDGATDLFVGAAVDPQSPSWSGLKKRFERKLLAG
CQFFQSQLISDFDKLEKFMNQIAVESNKPILAGIFLLKSAKNAAFINKYVPGVDIPEHII
NRLAKAEKPLEEGIKIAAEQVQIASNICHGVHLMAIKREDLIPRILDMAEISPI
>A0A7L9CCW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetia bacterium|TrEMBL
MIKNSSDAKSDSNLEKILRSGQFAVTAELGPPRGSDRSAIEKKAELLRGYGDAFNITDCQ
TAVVRMSSIAAGRIVLDAGLEPIIQMTCRDRNRIAVQSDLLGAAALGAKNLLCLTGDHQK
FGDHPMAKGVFDIDSIQLIHMVKTLRDESKFQSGQELKTAGPRFFIGAAENPFADPFKFR
AIRLAKKIAAGADFIQTQIIYNTKKFKEWMKMVADMGLHEKAFILAGVAPLKSVGMARHM
KHNVPGMDVSDEIINRMTAASAAKKGKEEGIRICLEVIEQVREVKGVAGVHIMAVEWEEA
VREIVQQAQLYPRPRLENL
>A0A845SQL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acerihabitans arboris|TrEMBL
MSFFHANQREALNQNLAELQGNINVSFEFFPPRTGEMEQTLWQSIDRLSELKPTFVSVTY
GANSGERDRTHGIIKDIKERTGLDAAPHLTCIDATPDELKKIAEDYWHSGIRHIVALRGD
LPPGSGAPAMYAADLVTLLKKVGDFDISVAAYPEVHPEAKSAQSDLINLKKKVDAGASRA
ITQFFFDVESYLRFRDRCVATGIDTEIVPGILPVSNFKQLQRFAAMTNVKVPSWMTSMFE
GLDNDAETRKMVGASIAMDMVKILSREGVKDFHFYTLNRADLTYAICHTLGVRPQVASA
>A6EEJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp. BAL39|TrEMBL
MFLDKIKSGVSGILTYGITPPKSETLPERIAEIAERTIARLIPLDIDALIVYDVQDESAR
TTEERPFPFLKAYDPFNFAREYLQALEIPKIIYRPAGKFYKEELSEWLEHLHQHHFYPVF
VGVPAPDFPVKISLPEAYDIWSKHKATSVMGAVTISERHEVLKDEDKRILDKAACGVSYF
ISQCVFDVAYAKKVVEDLCKTCRETQAVPPTMIFTLTACGSAKTLHFMEWLGIHIPAPLK
EELRHSDNMLERSVNVCLDIAEELMEFCSKQCVPFGFNIESVAIRKDEIEASIYMVNQIA
EKLKKKGLRETAAVSTGGTP
>A0A436IZU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.002.03.2.1|TrEMBL
MNDMRQELIQTRGSATFVFDAEVSIELAPAQARTFAPPADCFPLGSRVFLTHLPGKPEAL
QIEAARRIKELGFVPVPHLGARNFNSEQDYVDLVTAHSRNGISEALFLGGNPALFPGPLG
EATQLLAHPVVKDSAIRTAFVAGYPEGHPSIVEAVLTDALRRKLDICAERSLEARVVSQF
AFDGDMIAAWASSLHTAHPGLPVHVGLAGVTSLTKLIRFAMMCGVGPSIAALRRSASGLF
NIVADRNPAEILQTMAASYPAPTAPLHLHFFPFGGWEKTLAWFADYREACWPRVNER
>A0A1I1B6Y6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Algoriphagus aquimarinus|TrEMBL
MKITEHLGSAKETLFSFEILPPLKGQSLKELLEGISPLMDFKPPFVDVTYHREEYIYKKH
PNGLLEKISTKKRPGTVGICAAIMNRFHIDAVPHLLCGGFTREETENALIDLNFIGVENV
LALRGDAPKSEGKFIAEAEGHGYASELVEQILRMNEGRYLHEETEIGFQTDFCVGVAGYP
EKHFEAPSLKFDLKYLKEKVEKGAEYIVTQMFFDNQKYFEFVDQVRAAGISVPIIPGIKP
ITTLGQITMLPRTFFLDLPDPLMDELYKCKTNAEVKEVGIEWSIQQCKELVKQNVPSLHF
YTMSKADTTYKIAKEIF
>A0A2W4WCU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shackletoniella antarctica|TrEMBL
MFLASAPLGYRLRTAAKAGEFLVTAEVMPPKGGSPEHMLAMGQLLKGRVHAVNITDGSRA
VMRMSSWAAALLLQQQGIEAVCQVACRDRNRIALQADLMGVHALGVRNILALTGDPVKAG
DHPEARAVFDLESVRLLKLLGQLNGGVDSHDKPLADGALDLFAGAAIDPQSPSWLGLQRR
FEAKVKAGAQFFQSQLITDFDRLAKFMDQVAADYSRPVLAGIFLLKSAKNANFINRNVPG
AHIPQAIVDRLAAAADPLQEGVQIAAEQVQAARQLCQGVHLMAVRREDLIPQILDQGGVA
PVDALAQQ
>A0A2T4HFI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium columnare|TrEMBL
MKVTEHIANASGKTQFSFEILPPLKGQNIQCIFDGIDPLMEFNPPFIDVTYHREEYEYKE
LGNGLLQKKIVKKRPGTVGICAGIQNKYNVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKDGNGYASELVKQISDLNNGKYLDADLQNTNATDFCIGVAGY
PEKHIEAPSLDSDIHFLKQKIANGADYIITQMFFDNKKFFDFVSKCRKAGINVPIIPGLK
PIATKKQLNLIPHRFSLELPDDLIMAVVKAKDNEAVKQIGIEWCIAQSKELVKAGIPVLH
YYSMGKAENIKAIAKEVF
>A0A496SKW7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Latescibacteria bacterium|TrEMBL
MKTKSNLERVLKAGHFAVTAELGPPRGADPEAVRKKAKILKGYADAFNVTDGQTAIVRMA
SWAACLVAKEEGLDPIVQMTCRDRNRIALQMDVLGVAALGINNILCLSGDHMSFGDHPGA
KGVYDIDSVQLVKMVKDMRDEKKFQCGEEMEVEPRLFIGAAANPFAQPYDYRPYRLAKKV
AAGADFVQTQIVFNLDRFKEYMKRVCDMGLHEKVYILAGVSPIRSYGAAKYMATKVPGLD
VPEEILERMRKTPKGERAEEGKKICVEIIQQVREIPGVRGVHIMAIEWEEAVPEIVERAG
LLPRP
>A0A7V9GS70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoleophilaceae bacterium|TrEMBL
MRIDRILEEQRPCFSFEFFPPKTPQGEENLENALQELREDEPQFVSVTYGALGSTRERTI
DITKHIKQDLGMEAMAHFTCVGATTEELRGTLAEMKAAGIDNVLALRGDPPEGEEKWTQH
EGGLQYSTELANLISSEFPFAVGAACFPEVHPEAESPESDLRFTKAKIDNGVGFLITQLF
FDNDLYFDFVAKAREAGIEVPIIPGIMPVTNFKQIKRITGLCGATIPPEFERELAERQDD
LDALVELGVAYATLQCADLLSRGAPGIHFYTLNKSPATRAILAALRAARPWDRALAPA
>A8SPV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprococcus eutactus ATCC 27759|TrEMBL
MNILESLRDKLLVADGAFGTCYAGMYGERGTVAPELANMRHPERVLEIHKEYVKAGAGII
RTNTFAANTASLDADMDYVISNVRAAVKLAKQAVAETGAPGIDRKKAYVAGDIGPIPADA
GLTLNERVSQYKLLGEAMQDMGVDIIWFETFPEFNVLEPVVKQLKARKDTPVMVSFCVNQ
FGYSNCGFSARALLSQAAANSDVDCVGLNCGVGPYHMLQLLKKLDIDCGKPVSIMPNAGY
PKFTQSRLVFNDNKEGFIDKIQDIAALGADIIGGCCGTNPEYIRQIKESVKKGDIVKAAK
VHVEKQQFDNAPKDNFLKGRLKSGKAAVKNAGGHKLIAVELAPPVDVNDQKLLDAAHILK
QSHVDVVTFPDSPSGRTRADSILMAEKVHKETGLRVMPHLCCRDKNAIAIRGSVLGAQLN
GIKDFLVITGDPVPVMFRQTTRSVFNFDSVGMMKLLQTMNEEVFIGDKITYGGAINQNRI
NTKFEIDRIKRKLEAGAEFFLSQPVFSREQAQILRDMKAETGATILVGIMPLVSRRNALF
MKNEMTGIEIPDEIIERYGENATRQEGEDCGIQIAREILDYTADFADGYYFSFPFNRVHM
LAHIVD
>A0A6N7X451|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus alactolyticus|TrEMBL
MSRLLECLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDNISAIHQAYLEAGADVIQT
NTYAAKRHRLKGYGYDEQVKAINQAGVELARKAAGEDAFVLGTVGALRGLKQCDLTLDEI
IEETLEQVGYLLETKQIDGLLFETYYDEEEIIEVLKAVRPLTDLPIITNIALHEAGITEN
GRPLVELLGTLVMLGADIVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFEDDN
GSGHYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKCAIKGLKPVEKKFVTP
MVEEAELIKRVKSSETLVDRVKREVTIIAELDPPKTLDISKFTAGVKALDAACISAITLA
DNSLAKTRICNVSLASLLKNEIATPFLLHLSCRDHNMIGLQSRLLGMNVLGFDNVLAITG
DPSKIGDFPGATSVYDATSFKLLELIQQLNHGQGYSGASVKKATNFTAAAAFNPNVKNLS
RCGRLIERKIASGADYFITQPIFNADIFEELADLTKDYETPFFVGIMPITSYNNAIFLHN
EVPGIQLSEAFLAKLEAVKGDKETCQQLALEESKRLIDRALEHFNGIYLITPFMRYDLTV
ELVDYIHQKVEQKQLVIS
>A0A7C2E7P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MTERNRTFSFEFFPPRTPEGVAKLRTTRQQLAQFKPEFFSVTFGAGGTTRDGTLSTVLEI
RNEGYAAAPHLSCIGSTRDNIRSILNEYRNHGIRHIVALRGDMPSGMVEAGEFRYANELV
AFIREEHGDHFHIEVAAYPEFHPQAKSAEDDINNFVRKVNAGANSAMTQYFFNADSYFRF
VDEVQARGVDIPIVPGIMPIANFGQLCRFSDMCGAEVPRWLRLRMQAYMDDSASIRALGL
DVVTELCDRLLANGAPGLHFYTLNQAGTVSTIWQRLGL
>A0A523C2U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridia bacterium|TrEMBL
MVESLGLKERVKEKLEQKANTFKEVILSPDIFCVTWEQIPGRGAFELQQAEIIDNAERAA
RGSRIHAMSVTDNPGGNPALSTEMLCAELKRLGMEPLVHLACRDKNRNEIESILYGLAAE
GVRNILVLTGDFPSSDAFNGRPKPVFDLDPVHVLQLVKTVNNGLEHEVMGKKKTLAPTDF
FAGASVSPFKQLESELMGQYYKLDKKIQAGAGFLITQVGYDARKFHELLQWLKMNKYNIP
VLANIYVLSYGAARAMNANQIPGCVVTGKLLAELAEEAKAKDKGVSARLNRAAKMYAVAK
GMGYAGAHIGGQGIRYDMVEYIIEKGEELSKNWRDLVPEFDYPQNNGFYFFQKDLESGLN
LEKPALRVRRPSLQPMYGISKLAHALFFEPKNPVFKMLKPIATVIDSRPTLRRVFSSFEH
LGKAALYGCMSCGDCALFDIAYLCPMSQCPKNQRNGPCGGSYMGWCEVYPNQKRCMWVKA
YERLNGHNKAEEIGGYIVPPCNWELWRTSSWLNFYFGRDHATKIIKTKSAS
>A0A8J3TIG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planosporangium mesophilum|TrEMBL
MPDDRPSIGDLVRSSGPTFSFEFFPPKTADGERLLWQAIRELESLRPSFVSITYGAGGST
RDTTISVTERIATETTLLPMAHLTAVNHSVAELRRVIGNYAEVGIHNVLVLRGDPPGDPQ
AEWVAHPDGLHYASELVELVRRSGDFCVGVAAFPEKHPRSPDLDTDVDYFVRKCRAGADF
AITQFFFRWEDWARLRDGVAARGCDVPIIAGVMPVTNVKQIEKMAQLSGAAFPADLAARL
RAVADDPAAVREIGVEVATELSDRLLAEGAPGIHFITLNRSTATREVWQNLGVHTAAR
>A0A3S1T137|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.001.05.1.1|TrEMBL
MIGRQRDENPAGIHLPLEPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRTYMQKVRDLGYTEKCFILV
GVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEISGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQVDMVK
TAH
>A0A197JJ92|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Linnemannia elongata AG-77|TrEMBL
MKVIDKIRRADQEQRPYWSFEYFPPKTTAGVQNLFERMERMYNLGPEFVDITWNAGGTSS
DLTTELVATAQSVYGLETCMHLTCTNMPKEKIDAALKAAKACGNQNILALRGDPPRGQEQ
WVSCDNGFAYASDLVAYIRQQYGDYFSIGVAGYPEGHLDSIDREDDFKWLKYKVDQGADF
IVTQLFYDTGLFLDWVKECRTRGITVPIVPGIMPIQSFGGFNRMTSLCKTFVPDRIKDAL
EPIKEDDQAVKDFGVKLAVEMCKDIQAGGISGFHFYTLNLEKSTRLILEGLGFVAPRENA
RPLPWNPSLSKKREKENVRPIFWKNRIQSYVSRTEAWDEFPNGRWGDSRSPAFGELDGYG
TSLKVAPKEALELWGHPSSPREVASLFAKYCYGEIRSIPWSDESSLYPETEAIRGQLAHL
NERGYLTINSQPAVNGVRSDDKVHGWGPKNGYVYQKAYLEFFVSPENLNELVSRIEEEPQ
ITYYAVNKRGDLRTNSQNDGPNAVTWGVFVGKEIVQPTVVEVVSFVAWKDEAFELWSEWS
KIYEPSSESAKVIDNIRDEWYLINIVHNDFQDQDGLFRVLESVKTIDSEASVATTNGQRE
GALC
>A0A539EGU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium|TrEMBL
MLIPELFTKGRPVFSFEFFLPKAPEDMGKFKETVRELKSLGPDFVTITYGAGGSGREQTI
ETAGMIKAELGLETASHLTCVAHTKAEIRAVLARLKTLRIENVVALRGDSPKDGSALPVE
RRELPYAADLVRLVRAEGGFAMAVAGYPEKHPEAASPEADLARLKEKVDGGGDWVITQLF
FDNKDYFDFVRRARAAGVTRPIVPGIMPVTGYAQTKRFTEMCGAKLPPALLAGLAPIAED
KEAVVRFGVEWATRQCRELLAGGAPGVHFYTLNRSHSTEQVLQNLRRG
>A0A523H298|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MESQKKLTRTFSFEFFPPQTLEGVERLRATRRQLAQLNPKFFSVTFGAGGSTRDRTLETV
MEIQAEGYTEVAPHLSCIGSTSENIRYLLQKYLDSGIHYIVALRGDLPSGMAHPGEFRYA
TELVAFIRKEFGNVFHIEVAAYPEYHPQARSAQDDLHNFKLKVEAGADSAITQYFYNADA
YFRFVNACETASLRIPIVPGIMPINKFSQLARFSDACGAEIPRWLRKKMEGYGDDSASIR
AYGLDVVTDLCSQLLEAGAPGLHFYTLNSAGLTTTIWQRLGLQIQSQ
>A0A1M6RLU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Selenomonas ruminantium|TrEMBL
MKRVSVELIPRDEETLRGELQLLKQYEGKIDVINIPDLLRFDTRSWEGSAIAQEYFAMSM
PHIRAMDIDLDKELPMKDYLREKGIKEVLVVQGDPPQRMTHEVYPTESTDVIRKFREEMP
EVKVYAGIDQYRSSMRHELYRTRRKVQAGAAGFFTQPFFDMRMLEMYMDMLDGLDVYWGV
SPVVTPASQSYWERKNNVIFPKSFNPTLEWSVDFSRQVMEMADKAEANVYLMPIKTNLEE
YLAGVFA
>A0A1M6W781|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius marisflavi|TrEMBL
MKTPRISFEFFPPKSLEASFRLWDTVQTLAPLEPRFVSVTYGAGGTTRELTRDAVGTLHK
ATGLNVAAHLTCVDASREETLEIADQFADAGVTEIVALRGDPPKGAAGFAPHPQGFGNSC
ELISALADTGKFIIRVGAYPEKHPEATSQQADIDWLKRKFDAGASEAITQFFFEAETFFR
FRDACAKAGINASIIPGILPVENWTGTRKFAAACGTQVPAWLDDAFGKAIRDDRHDLLAT
ALATELCSDLIEGGAEDLHFYTLNRPELTRDVCHALGVTPKVELRHVA
>A0A536XMT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
EVACYPEFHPQARSPHEDLRNFKRKVDAGADAAITQYFYNIDSYLRFIDDCEGLGIDLPI
VPGIMPIGNFAQLARFSDACGAEIPRWLRMKMQSLGDDVASIRSLGLEVVTDLCDRLLSA
GAPGLHFYTMNQAGLTSTIWQRLGL
>A0A536TC36|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
GLDVVTDLCANLLEHGAPGLHFYTLNQAGLTTTIWQRLGLS
>A0A536WK01|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MDLATKDHSSNSAISELQRHLQDGSFVVTAELSPPVSTDPAEFIDHALALRGLVTAVNVT
DGAGSRAHMSSLAAAHFLVRSGVEPVLQITCRDRNRIALQAELLGAAALGIRNILALRGD
DPTLGDQPDTKPVFDLDTTALLATAQQMRSEHRLPSGTVIKGAVRFVLGAAELPVDPAPD
WRPNGLLSKMEAGAEFIQTQFCMDPEAVRRYAARLLDLGVAQRLPILIGVAPIPSARSAR
WMKEKLFGAMIPDAIVERLERAADPKAEGRRICVELLQQLAETPGVAGAHVMAPAFHSAI
GPVIETSRVAGTKRARARRG
>A0A521VW23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MARNGRVFSFEFFPPKTPEGKDKLRATWQQLARLGPRFFSVTFGAGGSTREGTLETVLEI
RAAGHEAAPHISCVASTRAEIAAQLERYRAHGIRHLVALRGDLPSGVAAAGEFRYANELV
AFIRESTGDWFRIEVACYPEFHPQTRNAADEVRNFKRKIDAGADAAITQYFYNADAYFRF
VDDCRAAGIAVPIVPGIMPIGNFSQLARFSDACGAEIPRWMRIKLESYRDDSASIRAFGL
EVVTALCEKLLAAGAPGLHFYTLNQAALTTAIWQRLAI
>A0A197K273|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Linnemannia elongata AG-77|TrEMBL
MKIIDRIKKGQEEGRPLFSFEYFSPKTAQGMVNLHDRIERMCYLGPEFIDITWGAGGSRP
AATLEVVSNAQKVYGVETCMHLICTNNPTDKIDKALSEARACGNQNILALRGDPPHGQSE
WTACEGGLNYAADLVRYIRKTHGDYFGIGVAGYPEKHPESATMEEDLKFLKEKVDAGADF
IVTQLFFDVPKFLDWVRQCREAGIHCPIIPGVMPIQAYASFKKNIVGVSVPQWILDGIEP
IKNDDQAIRAFGVEVGIKMTLELIEGGVCGIHYYTFNLERSTRLILEGAGLVNKTDYIKK
NMPWRSSFDEKRKEESVRPIFWSNRAKSYISRTDAWDEFPNGRWGDSRSPAYGDLDRYGV
YLKYTSDEAIQHWGSPSALQDICRLFVKYCTGETLTLPWSDQALALESGTIKDRLIELNS
AGYLTINSQPAVNGAKSDDKIFGWGPKGGYVYQKAYLEFFVSPETLEKLKQRMSKFPNFT
YNAMNKAGDLHTNTNGSKPNAVTWGVFPGREVVQPTIVELSSFDAWKDEAFALWEQWSRC
YPQQSKPRELLNELGQTWYLVNIVNNDYHEKEGIFEIFKEDVIAVQQQQQADAQAEAAVA
AKLQDLAISASGDVAPQVQAMAVAEAVKA
>A0A536T020|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MSFPASATEPRLEARISELVAAGSLEISPRELHRAKEVAALLPSGSCVYIPSLPGLPLTR
TLDAIAAIRDAGLDPVPHVSARRILNRDEFRDFLRRAATDYGVHRVLLIGGDESRAKGPF
ADSLQVLEERLLAECGVREIGVAGYPEGHPRIPANAIDKALERKLELAAAQSIGVYVLTQ
FSFAPPRVVEYCASLARRWPNLPVYVGIAGPTDPAALVRYAQRCGVSRSFRALRTLGTGI
AQLVTNTDPRDQLVSVARYTRAHEPSNAVGVHIYSFGGAVRAAAWMRERL
>A0A536YZC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium|TrEMBL
MDLATKDHSSNSAISELQRHLQDGSFVVTAELSPPVSTDPAEFIDHALALRGLVTAVNVT
DGAGSKAHMSSLAAAHFLVRSGVEPVLQITCRDRNRIALQAELLGAAALGIRNILALRGD
DPTLGDQPDTKPVFD
>A0A7X0SDP1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium gasigenes|TrEMBL
MNIRELFEEKNLVFSFEIFPPKASSSVETIYNTLEELKDLTPDYISVTYGAGGSLTENRT
CELSSLVKSKYGIESLAHLTCINSTKEEIDFLIRDLKNAGIENILALRGDMTSHKLSKGE
FNYASELVNHIKRRGDFNIVGACYPEGHIDCKDLDRDILNLKLKEEAGASHFISQLFFDN
NYFYDFLEKKEKYNIKSPIQAGIMPVINKKQVERITSLCGTNIPKKFLKIMDRYEHNKEA
LRDAGIAYAIEQMVDLISSGVDGIHLYTMNNPYVAKRINGSISSIINSVNNGNAI
>A0A1H8JU09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sophorae|TrEMBL
MKLDLRSAWAAKVLVGDGAMGTFLYQKGFPVGISYEELNLTSPEVIEEVHRSYIEAGAEL
LESNTYSANYDKLSKFGLESKVKEINRAGIRIARKAAGSTGYVVGAVGSIRAGKRASLSA
SELKKYFGQQIGAMLEEDVDGILLETFYDLEELHLALRTARKLSNLPVICQFAVDETAMT
MDGLTLPEAFRVLEEDGADVIGFNCRTGPIGIKRALGTLQGKLTLPVSVYPNAGLADYVD
GHYKYGASPEYFGEMASAFADMGCRIIGGCCGTTPQHIAEISAALTGYEPLPLPEAVQRE
KTSVRIQESLADDSFADGGEPTLIDLVKERHTVIVELDPPRDLDISKFMKGAEALRRAGA
DALTLADNSLAVSRMCNMALGSLVQQKTGLRPLVHIACRDRNLIGTQSHLMGLDALRIDH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKALKQKAKFVIGAAFNP
NVKHLGKAVERLEKKIAFGADYIMTQPVYDKELIHTIADSTAHLNIPIFIGIMPLASGRN
AEYLHNEVPGIQLSEEVRSRMKGLEGEAGRAEGVAIAKELLDAATERFNGIYLMTPFMFY
EMSVQLMEHVWAKSGRQLSPLFR
>A0A854C472|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Phocaeicola plebeius|TrEMBL
MKVIDLIKNSKEPVFSFEILPPLKGNSIQKVYHIIDKLREFDPKYINITSHHSEIVYLPQ
PDGNLKKTTVRKRPGTVAIAAAIQNKYGIQAVPHIICKGFTKEETEYALLDLNFLGINNL
LLLRGDSKPLDIAEKDLCLYHEHATDLQEQVNRFNQGIGLDGSKIEGIETPFSYGMACYP
EKHEEAPNMESDLFYLKEKVRNGADYVVTQMFFDNEKYYAFVERCRQEGIEVPIIPGIKP
VVFKNQLNVLPKVFRTDIPEAFASELRKCTTDEEVKAVGVEWCKAQCKDLLAHGAPGLHF
YTFMASDSVYKVAKEVY
>A0A363D7K0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter lacus|TrEMBL
MFETLIQKLQEDKYLTLETTPQHEPSMHNIIEKIKKFNLQDKIDGFSCTDNPLAKLRYNS
LFAALKLQQEFKKPVIATMTMRDRNKIALQSDLLGANDFDVRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGHPFKIEPKQIFPFAVVNSYAKNFSSLEKKMHLKI
QNGAIGIITQPIFDIENAQKLLESFDIAKENVEGDKRKSQLIFGLFPITKLRTALFLSAQ
VPGIHVPQFWIDALEKAHNIGEEEEYKVGMELSNNLFKELNKLHPKIHLMTANRFDVANE
IIS
>A0A1R1AC75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. FSL A5-0031|TrEMBL
MKPDLREALQQRILTGDGAMGTYLYQMGFPVGVSYEEINTNRPDVIENIHRRYYEAGARV
IETNTFSANLEKLSKYGLEDEMDAINRAGVRAARAAIGNDAYVVGAVGSIRDGKLKNLRT
AKVIEAYQRQMHALLDEGVDGLLLETFYDLDEMLLALKIARAASNVPVICQFAVEDVGRT
QDGNGMKGAFDLLQEEGADMVGFNCRSGPNGIMRAIDSITGPVGLPLSVYPNAGIPDYID
GKYTYPAGPEYFAETALRFADRGARLIGGCCGTTPEHIKAIAEALDGYIPQLGQAAVHSA
AAERIVVKPVEKSADTAEAAPLKQTVQEPNIVDLVQKRHTVIVELDPPRDLDIRKFMAGA
AALKEAKADAVTMADNSLAVTRMSNIALAALVQEKVGIRPLVHIACRDRNLIGTQSHMMG
LDALDIDHVLAVTGDPARFGDLPDSSSVYDLTSFEMIRMIKQLNDGTAFSGKPLKQKAKF
VVGAAFNPNVKHLDKAVQRLERKITSGADYIMTQPVYDPSLIERIAESTKHLSVPVFIGI
MPLASGRNAEYLHNEVPGIQLSDEVRQRMAGLEGEAGRAEGVQIAKELLDVALPHFNGIY
LITPFMFYDMGVQLTKYVWEKTERTQLNR
>A0A561PPC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga polysaccharea|TrEMBL
MLKEKIHQPGSNLVFYSLTPPKATTQPEQVKIIAGKQIERLQGLPIDGLLLYDIQDESTR
TEKERTFAFQSTITPEEYSKNYLASLQVPKVIYKSIGNLDKEQFTTWLQANQHIGYAVFV
GASSHQQVEATNFSLQDAYDLRNQYAKSLVLGGVTIPERHTKKGDEHQRIFNKINKGCSF
FISQCVYSLNDTKNLLSDYYYAGLDNDKMLSPIIFTLAPCGSLKTLQFMEWLGIEVPKWL
YNDLKHSKDILSSSIETCKNIAIEILNYTQAKNIPIGFNIESISIKKEEIEAANELLKDV
LQLAKSTGTSAGSLDLAKHTDKLQMIS
>A0A7W5ACF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes campanulatus|TrEMBL
MSLGLPSRLPGAPSVGELIRGPAPTFSFEFFPPKTPAGEQLLWQAIRELESLRPSFVSIT
YGAGGTTRDTTVAVTERVATETTLLPMAHLTAVNHSVAELRNVIGRLAGAGISNILAVRG
DPPGDPMGEWVRHPDGILYAEDLVRLIRAAGDFSVGVAAFPYKHPRSADVETDTRHFVRK
CRAGADFAITQMFFDAEDYLRLRDRVAASGSDTPIVPGVMPVTRMATIERSAQLSGAPFP
PALLERFERVAGDEEAVRALGIETCVEMCARLLDKGVPGIHFITLNRSTATREVWQQLAP
TEVATAA
>A0A285MB41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohaesibacter sp. ES.047|TrEMBL
MTPNAERSGRRSRSADKLKISFEFFPPKSPKMEAMLWESVQRLAPLAPEFVSVTYGAGGS
TRERTHATVERIIKEAGIPTAAHLTCVGATKEEVNDVIRSYREIGVKQIVALRGDPVDGV
GAKYEAHEGGYSGSPALVSGIKELGEFDVFVSAYPEKHPESSDFATDIELLRQKVDAGAT
KAITQFFFDNDLYEAFVERVRRAGIFIPIVPGIMPIHNFTQAAGFATRAGASVPQWLANR
FEGLENDADTHRLVSAAMAAEQVEDLHARGVDEFHFYTLNRANLVYAICHLLGMRPVKTA
TADAE
>A0A1H8Y4K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propionispora vibrioides|TrEMBL
MYIRELFYQRRKPVVSLEIFPPKPTLPIESVYATLEGLKELRPSFISVTYGAGGSNSART
IEIADKVKNHYGIEVLAHLTCVGLTREQITATLDQLAACQVDNILALRGDPPQGETVFVQ
PENGYRYAAQLVKHIKENGRFCLAAAAYPEGHIECRDMARNIEYLKYKVDQGADFLISQL
FFDNDSYYSFREQMERAGVQCPLSIGIMPVLNAAQIERITALCGAKIPAALQKLLDRYRD
SAEDMEKAGIEYACEQIADLQKTRFEGIHIYTMNKVAQVQSILQNTGLLNES
>A0A380EDH5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus aureus|TrEMBL
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGHSWWV
>D6JHR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli B354|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSNLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A0M2PW26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Prochlorothrix hollandica PCC 9006 = CALU 1027|TrEMBL
MFNRFRTAIQAGEFLITAEISPPKGGDPAHMLAMASTLKQRVHGVNITDGSRAVMRMSSL
AACVLLQRQGIEPICQFTCRDRNRIGLQADLLGAHVLGLQNILALTGDPVKAGDHPKARA
VFDLESVRLLTLITKLNGGQDWNDQPLPDGGTDLLAGAAVDPQLPSWSALAKRFERKVAA
GAQFFQSQMITDFDRFHTFMTDIAQDHGKPVLAGIFLLKSAKNAEFINRYVPGVHIPQST
IDRLAQAKHPLEEGVAIAAEQVQLAQELCQGVHLMAIKREDLVPHILDRAGIAPLPPLAT
ALPPLSAPTPALA
>A0A2V6GVN4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MDLLAELEERLVCGDGAMGTLLLDRGVPVDRCLEELCISDPDRIRAIHEEYVAAGARVIE
TNTFGANAIRLARFGLDNRVREINKAAVSLAKKAARGKEVCVAGSVGPLGISTHEAEERG
IDRAQCFREQFAALLEADVDLIFFETFLNFEEMEIALRAIPESDCAIVSLFACEPEGRLQ
SGMPLVDAFARCHDMGAKIAGANCLNGPRAMVQLFEKLPAGDLLAAYPNAGYPRYTEGRY
VYPTAPDYFAKAAREMAAQGARLIGGCCGTTPAHIAAVAKALVDLRPIKSKQVRAIAQPS
RTPVQIEHKAEESLLDKIASGKRVVICELDPPKTLALEKYFGGAQALVDAGCDAITLADN
SLAILRVSNLAVGAMLKERFDITPLLHLSCRDRNVLGLQSELLGMAALGMRHVLPLTGDP
ARVGDHPGAASVYDVNSVELISIIKQLNLGFTHAGKPLKAATNFVIGCTFNPNAKNLDAQ
VQRLERKVAAGAQFVMTQPVFDVDLVGEMHRRVQHLRIPIFTGVWPLQSAKQAEFLHHEV
PGIIVPDSVRAELGSHDGEGAQACGIRLAEKIITAALDFFPGVYLITPFLRYESTTRLAK
FARSL
>A0A396PZV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium OM07-11|TrEMBL
MKIIDKLNEDRIHISFEVFPPKTDAGFEKVKDATDKIAQLNPSYISVTYGAGGGTSKNTA
KIASHIKHELGVESLAHLTCASSTKEEVRQVIENLKELEIENILALRGDIVPGMTFPSED
RFHYAYELVEEIKKHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITTAAQMKRSQELSGTVFPRRFLALLDRFGDYPD
AMKQAGIAYATDQIIDLLANGVKNIHVYSMNKPEVAAKIIENLSEVIKC
>J7WVE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus cereus VD022|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNVSDPDLIISIHKQYVAAGADVIQTN
TYGANETKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLIDCGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPRFIEQGIRLLGGCCGTTPEHIQSMKRAVANITPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRERMDGHETKEAAIEEGIRISQELIDIAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A8E5U8E8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella sp. SJTUF14523|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LPPDSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A6H2D3I4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudodesulfovibrio sp. zrk46|TrEMBL
MRVCDLIERKSPFISLEFFPPKEKEAWPGFFEVVEKLKELNPLFASVTYGAGGGTQDNTL
EIATRMKRDHGIEPITHLTSVGASAEKLDEFLKSLREANIENVLALRGDAPRDVKDFDFN
TQEFKHATDVIEFINERYPEICVGGAAYPEPHPESPSIQSDLDMVDLKVKKGAQFLVTQL
FFDNRLYFDYVERLKSMGSNVPVIPGVLPIMSLKSAKFILGLCGAAIPGKFLSALEAAHA
EGGDDAVYRLGMDYAIKQAQELIDGGAPGVHLYTLNRAKACLEIGRNLKF
>A0A7C3GEX6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermosulfurimonas dismutans|TrEMBL
MSERRGFDEILRSRDFVVTFELVPGRSTRTRHYRHIIRFAEEVASKGLFDALSITDNAGG
HPALAPEALGRELRRMGHHPIIHFSCKDKNRNMIESDLLALDREGLHTLLVLTGDYPRYG
YRGRAKPVFDLDSVSLLRMVSEMRRGFRLSPEVPGGGVELPPIPFFPGCVVNPFKWSEAE
TLLQYWKLVRKVRAGARFVITQVGFCVRKFQELLFFLREEGLRIPVLAGILVLDIRLARI
LHRGVVPGITISTELLREVEKESQDPDRGREAALDRAAKLMAICRGLGFQGVHICGAPLD
VEAAHELLERSREYLPRWQEFLPQFRDHPRGAFFLYEEDRETGLNRPRRMPLTPKTRRGI
LYPFMELAHRVFFSSRSPLFPYLRRWADKLAHSALEKYFLHLEYALKKVLFDCQECGDCV
LPQMAYLCPQSQCAKFLLNGPCGGSRDGWCEVYPGKRRCVYVRIYERLKPEKRPYYLRDL
ELPPRDWALFRTSSWLNFYQGKTPRSTEPPEG
>A0A8I2D4A5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MRFIHDIYSDARQAGRPVFSFEFFTPKTESGDRAIFERTLPALCRLAPSYCSVTYGAGGS
TRAKTLQMVERIQLEFGVPAMAHLTCVGSTRDQIVALLDEARSRGISNILALRGDPPEET
GRFVRSDGGFEFAHELVTLTRDLGGFSIGVAGFPEGHLECREGKEVDWRRLAAKIGCGAR
FVITQLFFDNAFFYEFRDYLVGTLGITVPIVPGVIPILSSSQVERFVSLCGATIPSALAG
RLNALGDNDADVTEFGIEFATRQCADLLRQGVPGIHFYTLNRTEPTTRIVQNLRGG
>A0A3D9UTX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calidifontibacter indicus|TrEMBL
MVTRMSDASARPHPSIPDLLGAPDTAFSFEFFPPRDDASEAVLWDSIRRIERVHPSFISV
TYGAGGSTRDRTVRITGRIEHETTLTTMAHLTCVGSSVAELRQIVGQYAGAGIRNILALR
GDPAGGLGTEWTPHPEGLDHAEQLVDLIRGLGDFTVGVAAFPDKHPESGSLEDDAKVLIR
KADAGAAFAITQMVTDVDAYLRLRDLVDGAGRTMPIVPGLMPVTAYGQLQRMTQLNGQPL
APDVVERLEALKDDKVAVREVGVQICTEHAQRLIGEGAPGIHFITMNRSTATLEVHQNLV
G
>B2WHR5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pyrenophora tritici-repentis (strain Pt-1C-BFP)|TrEMBL
MEKITDKINSLPDGANYFSLEFFPPKTAMGFANLQTRLERMSQALRPLFVTVTWGAGGST
ATKSLELAEICQRQLGLTTCLHLTCTNMNRQLIDDALEQAKVLGIRNILALRGDAPRSEE
YRDEGTPPEQDSNKDFTWAIDLVKYIRKEYGDYFCIGVAAYPEGHSDQSHPEHQDPLTDL
PYLVEKTKAGADFIMTQLFYDVQAYDKFEKMLREHESGVFKTIPIIPGLMPIQSYKILLR
TTKLSHARLPAEMLARLDAVKSDDELVKQMGVQIMDEMVEHIKARPETCRRGFHFYTLNL
EKAVSHVVEDTHLIPTTIMDDEEIIVETTPAINLEPPPNGLMARRRRSSAVNSGPFNRVI
ISHGSGAKSSNHSYEATEEEAGVPRGPINTRANTLAISEGEGSLGREATWDDFPNGRWGD
ARSPAFGEIDGYGPTLHVSTPQALKLWGYPVEKKDISTLFRRHIEGDLEAIPWSEQGLSP
ETSTISAQLLALNAKGWWTVASQPAVNGVKSTDPIFGWGPKNGYVFQKPFVEFFIPAAEF
QAFKPKLQAHDQVTWFAGNAAGAFEASQEDGVNPVTWGTFAGKEIVTPTIIEAVSFRSWL
DEAFSIWKEWQRIYPPRSGSSVLLGELSKDVWLVNVIWGDFVNGEGLWEFLRQ
>A0A2V2S565|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
MHLVRDIYAAKADARRPVISFEFFPPKTPEGEVALLHKTIPALLETGPDFCSVTYGAGGS
TRDKTLKIVERIERERGFTAVAHLTCVCATQQQIGELLGQIRALGVRNVLALRGDPPNGN
EFQVTPGGFEYSSQLVRFIRAQGDFCVGVAGFPEGHIACKAGKHADWAYLNEKVDAGADY
VITQLFFDNADYFAFRDHMRQTHGMEKPLVPGIIPISSAAQIKRFTALCGARIPAPLAAK
LDELGENDAAVTEFGIQYATRQCEELLAAGAPGIHFYTLNKAGSTVRILKNLGLTP
>A0A3D1UC70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia bacterium|TrEMBL
PADMPGDFAHAVDLVRFLDGRGFCLGGACYPECHPECAHIADDLAHIKEKVDAGLDFLVS
QMFFDNNIFYAYLSKLLGRGIR
>A0A5C8WNT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Methylobacterium sp. WL8|TrEMBL
MPNAIRHRASRDGYHPIRVSIEFFPPKTEEMEKILWSSIERLAPLGPKFVSVTYGAGGST
RERTHNTVARMVTETGLKPAAHLTCVDATRDEIDAVVQSYWDAGVRHIVALRGDPAEGVG
HAYRPHPGGYAQTSDLVAGIKRIGDFKVSVSAYPEKHPEAASLDADIDALKAKVDAGADQ
AITQFFFENEVYLRYVDKVRAAGIDIPIIPGILPVQNFKQAANFARRTGASVPYWLAARF
EGLEGDVETRRLVAAAVAAEQVLDLVDEGVNDFHFYSMNRSDLVYAICHLLGLRAQAPKV
MAAKAA
>C1GYS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01)|TrEMBL
MHIKDKLAYAEATGHPGISFEFFPPKTAQGVQNLYDRMDRMHGYGPSFIDITWGAGGRLS
ELTCEMVNVAQSVYGLETCMHLTCTDMPREKVDAALQSAFKAGCTNILALRGDPPREKEK
WEATEGGFRYAKDLVKYIRVKYGNHFDIGVAGYPEGCEDQDDPELLMQHLKEKVDAGGTF
IITQMFYDVDNFLAWVKNCREKGIKVPIIPGIMPIHTYAAFIRRSNWTKIQIPPGWLEAL
EPVKNDDAAVRNLGKSLVANMCKKMLASGIHHLHFYTMNLQQATKMVLDELGLIPSHETP
LQKPLPWRQSLGLGRREEDVRPIFWRHRHQSYVARTQTWDEYPNGRWTDSRSPAFGELDT
YGIGLKGTNEQNIQLWGKPKSLKELSEIFIHFLNGKLDRLPWSEGAVTEETDIIKRDLLD
LNSRGFLTINSQPAIDGVHSSHPVYGWGPKNGYVYQKAYLELLISPTLIEDVIHRIEQNA
DLTYYCVNKTGELRTNTSDSPNAVTWGIFVSKEIIQPTIVETISFLAWKDEAYRLGDDWA
KCHPASSPSRRLIQQVMDTWYLVNIVNNDFHRTHDIFDLFKNLKVKDLDLEVEPIDPAAE
FVGNIDHNGQSPEKLANGRAESKPQTITH
>I3IHQ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Jettenia caeni|TrEMBL
MIENRSDIKSGSNLEKLLLSGQFAVTAELGPPRGADRSAIEKKAEILKGYGDAFNITDCQ
TAVVRMSSIASGRIVLDAGIEPIIQMTCRDRNRIAIQSDLLGAAALGLKNLLCLTGDHQK
FGDHPMAKGVFDIDSVQLIHMVKTLRDEKRFQSGQELKASEPKFFIGAAENPFADPFKFR
AVRLAKKIAAGADFIQTQIIYNVKKFHEWMNMVADMGLHEKVFILAGVAPLKSAGMAKHM
KHNVPGMDVPDEVMSRMTAASAAKKGKEEGIKICLEVIEQVREIKGVAGVHVMAVEWEEA
VPEIIQQARLFPRPTV
>C0NTN2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)|TrEMBL
MEKISDKIANLPPDANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRTLVDHALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFTWAVDLVKYIRRTHGDYFCIGVAAYPEGHSDESYPEVQDPVKDLPYL
IEKTRAGADFIMTQLTYDLGAYKRFEEMLRNHESGVFETIPIITGLMPIQSYHILTRTTK
LSHARVPPDIMARVEAVKSDDEEVKRIGVDILCEIVNGLKQVSYPGPRGFHFYTLNLEKA
VALTVEKCNLIPPLSPLPSDSETYMDTAVFMAQGKQNGISLLSKRRASSMNSQPHNRLIV
DRPSDAGGSSQASTTHETPALGAGMPALNPPPRTTTLQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVNAAVARRLWGYPTTKQDINNIFQRHVSGELHLVPWSEGGA
QDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAF
VEFFCPAHDFESILKPIFESHSHDEFAWFATNAAGDFMSSSPATDATTEDSSGPVDVFLD
SNVSPGNTGVTAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRIFPRGSPTER
LLDQLKNDVWLICCVGQKYGAGCASLEAAEAEGKLLWKLLGGTGTGPDSVNNH
>A0A6B2VZ77|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID13666|TrEMBL
MSTLREILASGTRSFSFEFFPPKTDAGERSLWESIRRIEAVAPTFVSVTYGAGGSSRSRT
IAVTQRIAAQTSLRPVAHLTAVGHSVGELRRIIGQYADAGVRDVLVLRGDPPGDPRGAWV
PHPDGLNHARELVTLVKGSGNFSIGVAAFPERHPRSPDWETEVRHFVAKARAGADYAITQ
MFFRAEDYFRLRDRVAAAGCDLPIIPEIMPATDVRQIRRFAELSNATFPDDLAAQLAAAE
HDPDVAHRIGVDHATRLAQRLLDAGAPGLHYITLNRSTAALDIHRNIRSADAVPHRR
>A0A6B2W4T9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID13666|TrEMBL
MALGTASTRTDHAVTIRELLASGERSYSFEFAAPKTEKGERTLWNAIRRIEAVGPTFVSV
TYGAGGSSREGTVRATDRIVSDTTLTPVAHLTAVNHSIAELRNIIGQYADAGIRNILAVR
GDPPGDPLGEWVKHPQGLLYAADLVRLIKESGDFCVGVAAFTEMHPRSSDWESDTRNFVD
KCRAGADFAITQMFFDADDYFRLRDRVAAAGCTTPIIPEVMPVTNVRQIERFAQLGNAPF
PPELADRILAVKDDPAAVRAIGIEFTTEMCRRLMAEDIPGLHFITLNHSTASLEIYENLG
LHQRS
>A0A7Y0LQ03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridioides difficile|TrEMBL
MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAANVTDFQSAVMRATSLA
TCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLLALTGDHTSVGDHPQAKGV
FDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTPEYSPIEVQLLKMKKKIKAGA
KFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSPGMAKFMTANVPGIFVPDEQIER
LRVAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIMAIGAEENIPAILDAAGL
>A0A6I5R4V8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptolyngbya sp. SIO1E4|TrEMBL
MVANLPLQKSPSGSQFQAAIRAGEFLITAEVMPPKGGDPSHMVAMAQNLRGRVHGINITD
GSRAVMRMSSLASAVILHQKGIEPICQMACRDRNRIALQADLLGAHALGIRNILALTGDP
VKAGDHPDARSVFDLESVRLLRLIQQLNHGFDLNDRPLTSPPTQLFAGAAVDPQSPSWSG
LQRRFAKKIEAGAQFFQSQLIDDFERLEKFMDQIVAGCDRPILAGIFLLKSAKNARFINR
NVPGVQIPEHMIERLAKASDPLQEGIRIAAEQVRAAQDLCQGVHMMAVRREDLIPQILDL
AGVKPLVSGHHMPPEQRVEVANSANS
>A0A7Y7VNR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. B9002|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATRDELRGIARDYWDSGIRHIVALRGD
LPPGSGKPEMYGSDLVELLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPGWMSAMFE
GLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPAIGG
>A0A7W3Q6K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aminobacter ciceronei|TrEMBL
MLNRAPAVTALDKEMWRKILSRCSLEVPVSRAADFVPAHDVFQKGSFVFLPHISDLDSRG
MENASRHLVDSGYVPVPHVGARHFASESAFLSHLRGAREGGARHLLVLSGDRDAPAGPFT
SALNILAHGAIKDFGFQRVFISGYPEGHQRISNDALERATRSKIEVMQDSGVNVSIVTQF
GFASSAYRIWLHRIRQNGIRCPIRLGLAGVTSIPSLLKYAALCGIGPSLSVLRKRSGAIA
GLVKGYEPSGLIAELNRELDIANHDQLNLHLFPFGGAAKTIEWFRTRIGAPNA
>A0A4S3M2L3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Robertkochia marina|TrEMBL
MKVTDHIKNANGKTLFSFEIIPPKKGSNIDELYRNIDPLMEFDPPFIDVTTSREEYVYIQ
KDDLLERKITRMRPGTVGICAAIKHKYDVDTIPHVLCGGFTREETEYLLVDCHYLGIDNV
MALRGDAMKHQRYFEKTEGGHEYASDLVKQIRDLREGKYLHDTAEAGAMADFCVGVAGYP
EKHLEAPSLESDLKKLKLKVDMGADYVVTQMFFRNEAFFEFVDKARAMGITVPIIPGIKP
IAVKKHLQLLPQVFKIDLPEELISEVEKCSTNKEVRQVGVEWCIQQSRELKEAGVPVLHY
YSMGKSDNIKDIASALF
>A0A022MIT3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. Tu 6176|TrEMBL
MALGTASTRSDHARTVRDMLATGKTTYSFEFYAPKTPKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKATEAIASDTTLTPIAHLTAVDHSVADLRNIIGQYADAGIRNMLALR
GDPPGDPMGEWVPHPRGLRYAAELVELIKTSGDFCVGVAAFPAMHPRSADRDTDVRHFVD
KCRAGADYAVTQMFFDPEDYLRLRDRVAAAGCETPIIPEIMPIASVKTLARIPSLTNAVF
PGALKERILAAQDDPAAVRSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
PHRSPRA
>A0A0M4Q5Q0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudonocardia sp. HH130629-09|TrEMBL
MTTSSASTVTERISVDRPFFAVEFFPPKDDQGEAELWRAIRRLEVLDPAYVSVTYGAGGS
SRDRTVRTVERIATDTTLCSMAHLTAVSHSTDELRHVIGSLAAAGVRNIMALRGDPPGDP
LGEWVAHPEGLEYADQLVALIKRSGPFCVGVAAFPYGHPRSVDLDADTERLVGKFRAGAE
FAVTQLFLEPEGFLRLRDRVAAAGFDQPIIPGIMPLTSEKTFRKGPELSGSPLPGALVER
LAPYSGDAAAIRAAGMEVTGELCERLLAEGVPGIHFYCLNRSTATTELVERLGLAPRHEG
ARHSTPA
>E4U1S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sulfuricurvum kujiense (strain ATCC BAA-921 / DSM 16994 / JCM 11577 / YK-1)|TrEMBL
MFETFIHKLRHDTYITLETTPSRSAQFAPTIEKIAALGLDKLVDGFSTTDNPLAKLKYNA
LFAAMKLQDRFGLPTLATMSMRDRNRIALQSDLLGANEANVRAILALTGDSAHYSDQPHA
KGVFEGNSKLLLDIITTLNRGTDIAEQKLLAPVQEIYPFAVIDSYAKSAATLQKKMIKKV
AHGAIAIISQPVYDIENAKQLLSMMESANEQSPHAEKSILVLGFFPITKLRTARFLDENV
PGIYVPHAWVEALEAASLISPEEEYRVGFELSKTLFEELKALHPKIHIMTANQFELAKAI
LS
>A0A095X341|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Achromobacter sp. RTa|TrEMBL
MSDSTTPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRT
LRNLGCDAAPHLSCVGATRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANE
LVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVRKVKAGANAAITQYFFNADAYF
DFVDRAQAKGVNVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAEFGDDKASIRAF
GVDVVTELCQTLLDNGAPGVHFYTLNHAEAPMAVWKELSLQA
>A0A381I7X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridioides difficile|TrEMBL
MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAANVTDFQSAVMRATSLA
TCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLLALTGDQY
>A0A1F4RLL2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|candidate division WOR-1 bacterium RIFCSPLOWO2_12_FULL_45_9|TrEMBL
MKVSEALDKGTPTLSFEFFPPKTEEQEAKLFKVIATLKTLKPDYVSVTYGALGNTREKTF
YWVKKIKEDFGLEPVVHLTCVAAGRDEILAQIRQLQEIKIDNVLALRGDPPQGDDEFVAP
AGGLAHASDLVAFIRRQVPEICLGVAGCPEKHPEATSFYSDILHLKAKVAAGADYICTQL
FFDNKAFFNFREKCQKAGIKVPIIPGLMPITSFKLLTKMTEMCGATIPDDLSAKLEKNAD
DHEAVLKIGVEQTVRQCQELLDKGAPGLHFFVMNQSSPISEILKEVPTFSRRR
>A0A7J7LY69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingdonia uniflora|TrEMBL
MKVVEKIREVSEKGGIVYSFEFVPPRAKKGDIDGFEQGVKDVLETIDRMVEHGPSFCDIT
WRAGGTNAERVLRIAKEMQNTIGVETMVHLTCMNMPLDEIDHALDTMKANGIQNVLALKG
DPPVGKDQSQTVENGFSCALDLVNYIKARYGDYFGITVAGYPEAHPDKIQSNGLADLDDY
KSDLVYLKRKVDAGADVIISQLFFDTDIFLKFIKDCREEGITCPIVPGILPITTYRGYLR
MIGICKTWVPAEVTAALEPIKGDDESIRNYGIELATKMCKKLLAYGIKTLHFYTLNQDKS
TLAILQNLQNLGLVDIRSNKDMYQNGEEYSSTILLAVVLGVAVSNIPLSTAYDAECVSIL
DVLLHAARFGFPNIWITTDSSSACIAFKSKSLPWKLQLLWNKLKRSYARIRITTVWREVN
FGSNAAAKRGTSLAWGESFVCWKTFIPGED
>A0A514Z9T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus protaetiae|TrEMBL
MVNNPKKMLSFEVFPPNTEVGTSKLFKTLDELKELSPDFISVTCSNNNRTDIGHTTIRVA
DYVNNTLNIPAVAHLSAAYLDKNQVKEILEQLKTKGIHQILALRGDITTLPTKNDFHFAS
DLVRFIRAYDETFEILGACYPDIHPESQNRVTDFHYLKEKVDSGCDKLITQLFFDNNTFY
DFQERCAIAGIEVPILAGIMPIVNRNQAIRLLKTCNTPLPKKFVRILEKYEHNPLALKDA
GIAFAIDQIIDLTTEDVDGIHLYTMNNAETAKSIHHATSSLFYQELS
>A0A7J7LYC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kingdonia uniflora|TrEMBL
MKVIDKIKEASTEDKVVYSFKFFPPKTEDGVDTMFDKMDRMVSHSTSFCEITWGAGGSTA
DLTLDIANNKKMQNMNVLALRGDPPHGYDKFVKTEGGFACAPDLVKHTREKYALTTHSMK
ACLLEFEFGLMKKKKRESLLGSTSCRLADEILRVSGVCDFEDHLRIRGNGGQFCFVCSGL
MGKMVIGYQVKGRDPLDYFGITVAGYPGCFVLCFHFANGWGGYGIEHIYVGQIWGSSLNL
NGDWGGDGRWEPKRGWGCIDLWKDNWCSQKSLKDHINNDNMPWGSMTASVSSIIVDGRWA
IPDDLSLIFHRLNINIMSIKINKNNADRRVLKPDLTGMLSAKGAFNVIINKGNLAWWSKY
LNRKAIHPRIAMWGWRLAHGSVPTDDNVRKKGICMVSKCACCV
>A0A6G3PV62|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID10692|TrEMBL
MALGTPSTRTDHARTVRDLLATGKTSYSFEFWAPKTEKGERNLWNALRRVEAVRPSFVSV
TYGAGGSTRAGTVKATQEIAADSTLTPVAHLTAVNHSVAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWIEHPQGVKYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPVIPEVMPLTSVKQLEKFSQLSNATV
PEALKERILAAKDDPAAVRSIGIEFATEFCAELLSEGVPGLHFITLNNSTATLEIYEKLG
LHKQS
>A0A087BIH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium merycicum|TrEMBL
MTSPLFSLEVFPPRRNAPVGTIYDTLDGLQGLAPAFISVTYGTGKSKDRTATARIANTIR
GEYGIPAVAHLTAQYLDKEAADVALDLFEVAKVGGILALRGDRVEGETPAGVFEYASDLV
TYIRKTRPQLKVYGACYPEKHPQAKTLDEDIDNLKRKVDAGVTHLISQLFYDNVDFYRFL
DKARAAGIDVPIEAGIMPVTNAKSVRRMSSTCEARVPESVEVMLQRWGENPATLREAGIA
YASQQVADLVAHGVDGVHLYTMNHPAVVRRIWNNVSGLFTD
>A0A855Y366|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus pabuli|TrEMBL
MKADLRSVMQERVLIGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
HETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGANGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLEEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGVPMSVYPNAGAADYVD
GQFRYGASPEYFGQTAVQFADLGARIIGGCCGTTPDHIAAIAQALVEYTPAPILEPDPSE
SKPRIILHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVSFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDPELIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATKHFNGIYLMTPFMFY
SMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A1Y2TNT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hypoxylon sp. EC38|TrEMBL
MEKITDKIAALPADSNYVSLEFFPPKTVMGFSNLRDRLDRMARALRPLFVNVTWGAGGST
ATKSLELAEICQRELNLTTCLHLTCTNMSRKLIDRALEDAKALGIRNILALRGDPPRAAE
YQGPNENPEDAIDETFNWAIDLVRYIRKTHGDYFCIGVAAYPEGHADESHPLGQSLEHDL
PYLVDKTLAGADFLMTQLFFDTEAYDKFERTLREHPSGAFKTITIIPGLMPIQSYQMIKR
TTKLSHAKIPDAIMSRLDAVKKDDEKVKSVGVDILCEIVEQVKQITSRTPGPTGFHFYTL
NLEKAVSFIIERTNLIPPTTPIEDEAVVEDIASKIPTLQINGSDHEHEHAPKTSRENSRT
RRQSNVSSEHRNRVIISGRPVSHPEYEATSAEASIPAEPINSRSNTLAISEGEGVLGREA
TWDDFPNGRWGDARSPAYGEIDGYGPSLHVSHAQAVSLWGYPAKREDINELFVRHLKGEL
TAIPWSEEELNEETRTITDKLVRLNSKGWWTVASQPAVNGLRSSDPIFGWGPQNGFVFQK
AFVEFFIPSAEWKILLEKLQSSEVQDTVCFYAANAAGDFVSSDLTGGLAGERKESSTNAV
TWGVFPGKEIITPTIIEEVSFRAWSEEAFGIFGEWAQVYGKGSESEKLLEKARADSWLVN
IIHHDYVDKDALWNLLLD
>A0A349J3B0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
EFFPPKSETAAERLWQSIGRLAPLRPDFVSVTYGAGGSTRDRTHQCVKRMIDETDLKPAA
HLTCVAASKAEVDSVVDDYAAAGVKHVVALRGDMPDMGLFQPHADGYDGSVALVAALAKR
GGFDITVSAYPEKHPESTSLDADIDLLKAKIDAGASRAITQFVFDTEAHLRFRDRLSAAG
ITIPVIAGIMPTTNFAGTKRMAEACGAHVPQWLSDAYEGLEEDADTRKHIAASVAIDQCR
KLIDEGFESLHFYTLNQADLTFAVCRILKLGAAAH
>A0A2E0P6V7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MASTIEMISKAATDWSIEVTPTGANKIESFRDCLPPGTTVNVTFLPGTDPAETIAVAERL
HNDGMRPVPHLAARSLRDADQLDELLTAFTSRCGVDEVLCIGGGVDKPVGTFDATIQVLE
AGLXQKXGIRSVGVAGHPEGSPDXXDEEXAXALAAKNALAARDGLNLYIETQFCFEADIV
LDWERRVRAAGNTLPIRIGIPGPATIKTLFRFAQISGIGPSMRFIAKQAKNVAKLMTVQS
PHMLIAGLAEGMAADDACLIRHFHYYPFGGFARTAAYAGAIAGGNXELLPKGGFDVIAN
>A0A2E6RSD1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MTNLNTLKPIINRVITGEKPGVSFEFFPPKTKEMEKTLWSSIDRLSNFSSNFVSVTYGAG
GSTRERTHKTIKKIIENTDLTPAAHLTCVGASKLSVDEVASSYWDLGVRKIVALRGDPPE
QSKKYAPHPEGYINAADLVKGIKGIADFDIFVACYPEMHTESKNFEDDLDNLKKKIDSGA
SHAISQLFFDDEIFLRWLEKVRASGISIPIIPGIMPITNFLSTVRFCKLCGASIPGWLKS
LFNNLDEDQETRKLVGAVVAAEQCRRLQAEGILDFHFYTLNRADLTYAICHILGLTQNSN
KK
>A0A212THY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp. es.048|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYKEHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGVMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDSDSIRK
FGEEVVTEMCEKLLRAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAF
>A0A2E4H1Q8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MVLAPTVSFEFFPPNSPKAEEQLWEVMKKLSPLGPAFFSVTYGAGGSTRNRTERLVERIN
NVMPVAPAAHXTCVGATRAEIEXLAQNLWNSGIKHIVALRGDLPKGELNYNARXNGYENA
AELVSGLRKIADFEXSVAGYPEMHPDSPNLAADIDNLKRKVDAGANRILTQYFFDNELFY
RFRDAAVAASIKIPIVPGILPVTNFARVVEFSTNCGTSVPALMAEQFKGLDDDPETRALI
AASTAIEQCENLLANGVNAFHFYTLNRAALTYAICWRLGMRPTKKNGPNAHAA
>A0A1F4BS69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_65_24|TrEMBL
MLAAAAPDRQAVKSGSGLERVLAQGDFAVTAELGPPRGWHPDSVKRKAQLLKGWVHAANV
TDNQAAVVRMSSIATGLIMIDEGLEPIVQMTCRDRNRLAMQSDLLGAAAHGVRNVLCLSG
DHQSFGDHPGAKNVHDIDSIQMLAMLRAMRDEGRFQSGGEIAEGGPQFFIGAAENPFADP
AAMRPYRLRKKAAAGAQFIQTQLIYDLARFREFMKKVVELGVHEKVSILAGVGPLKSPGM
ARYLREKVPGMSVPRSLDARLEGAAEGIDAGDKQALNRAWREEGKRICIELIREVREIEG
VAGVHIMAIEWEQAVPEIVKAAGLMPGAPA
>A0A1Q8IS49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia sp. SRS-W-2-2016|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRAELVTLKPKFVSVTFGAGGSTQQGTLAAVVDIAK
EGIEAAPHLSCIGSSKDDLRAILTEYRAHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQARSPRHDLENFARKVKAGANSAITQYFFNADAYFRFVD
DAHKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDRDSIRAFGLDV
VTNLCQRLVDAKVPGLHFYTLNAAAATKAICERLRA
>A0A2E0H666|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSVTKKEIASLVSDFSIEVTPASAERVEAFADHLVPGTSINVTFLPGSSFTDTIRVSRRI
HEEGFKPIPHLAARNFESSKALEQSLDNLTSHANVEEVLIIAGGLDSPLGPYHSTMQILG
SGLLEKYSIKKIGIAGHPEGSPDISNSDIDAALNDKNAWARNTDIEVYIATQFCFEASVI
LDWEARIKKLGNTLPIHIGLPGLATLKTLLKFAQMSGIGPSMRVLTRQTKNLAKLVMTQE
PDIVITDLTSRVARAPGSLIKKVHFYPFGGLAKTAAWANSVVNEQIEMKPNKGFKTYTDH
>A0A1V3QX94|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sinorhizobium sp. A49|TrEMBL
MPMTAFARHDLETALFHNYSLEITGKDIGQIEAARFAIPAGTPINIAFLGNETHAQRIEA
AARIRQWGFEPVPILSSRRLKSVEDRDELLAGLIVAARPTRFMFVGGDPSSPAGPYKDSL
DLIAGGIIEDHGITHVGIGGYPEGHPRIDRTRLWEALEQKIGLLKARGCTVEITTQFGFD
ADAIVDWIVRVRERGIDVPIRIGVPGPADVRRLLRFAVQFGVASSAAIVGKYGFSLANLV
DKVGPDRFMSRLADGMAGRNLGTVLLHLYPFGGIAETVAWAADAACRQMSESARVRGETR
>A0A2V1MDC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Kocuria rosea|TrEMBL
MPIDPPHAGPAAALLRDFSLEMTGKDVPALEEAAAVVPAGTRINVTFLGNEDLGMRVAAA
RAVREHGFVPVPHLSARRLRSQGELEEFLAALAEVGAAEHVFVVGGDPETPEGPYPDSLS
VIRTGVLPRHGVRGVGVSGYPEGHPGIDDAALWSALTDKTAAIREQGLEPEIITQFGFDK
DPVLEWLAEVRRRGVDTPVRIGVPGPAGVRRLLGYARRFGVGTSAGIVQKYGFSLTNLLG
TAGPDRFLRDLAAGLDPTVHGQVLLHFYTFGGLRATAEWVREFGTDGGTP
>A0A2D7FPC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobiaceae bacterium|TrEMBL
MTGISFEFFPPKSEAAGEKLWQAIDRLAPLSPDFVSVTYGAGGSTRDRTHACVKRMIDET
TLKPAAHLTCVAASKAEVESVIDDYAAAGVRHVVALRGDMPDMAAFKAHDDGYSGSVELV
EALAKRGGFDITVSAYPEKHPESASLDADIDLLKAKIDAGATRAITQFVFDTQAHLRFRD
KLAAAGITIPVIAGIMPTTNFAGAKRMAEACGAAVPQWLADAYEGLDEDLDTRKQIAASV
AIDQCRKLIDEGFGHLHFYTLNQADLTFAVCRILRLGAAAN
>A0A2E9X9J4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MSNASHHVSPPPVVPPRCDGMKVSFEFFPPKTKKMEQTLWAAIKRLKPLAPQFVSVTYGA
SGSTRERTHATVARIRHETNLEPAAHLTCVGANRDEVDAIASRYWEDGVRHIVALRGDPP
GQEDTYMPHPGGYAYASDLVAGLKNVADFEISVAAYPETHPESQNMQDDLDNLKRKIDAG
ASRAITQYFFDVDVFFRFLDRAAAAGVEVPIVPGILPVTNFARVTEFCRVCGTSVPLWMA
QMFEGLDDDHETRKLVAAAITAEQCKLLQARGIREFHFYTLNRADLSYAICHILGLRPHG
STGGGVAE
>A0A2D7D9P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MASTIEMISKAATDWSIEVTPTGATKIESFRDCLPPGTTVNVTFLPGTDPAETIAVAERL
HNDGMRPVPHLAARSLRDADQLDELLTAFTSRCGVDEVLCIGGGVDKPVGTFDATIQVLE
AGLIQKHGIRSVGVAGHPEGSPDISDEEVAEALAAKNALAARDGLNLYIETQFCFEADIV
LDWERRVRAAGNTLPIRIGIPGPATIKTLFRFAQISGIGPSMRFIAKQAKNVAKLMTVQS
PHMLIAGLAEGMAADDACLIRHFHYYPFGGFARTAAYAGAIAGGNIELLPKGGFDVIAN
>A0A2E7HJE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodospirillaceae bacterium|TrEMBL
MMDPGPVDPGAPLEPLPGHTSRGRLERILRAGEFAVTAELSPPDSADPMNVFERAAIFDG
WVDAVNATDGSGANCHMSSVGVCSLLTRVGHVPVMQISCRDRNRIAIQGDVLGAAAMGVA
NILCLTGDGVQCGDQPEAKPVFDLDCMATLEIIRTMRDKGELASGRKLDKAPELFLGAAA
NPFAPPYDFRPLRLAKKIAAGAQFVQTQYCYDIPLLERYMQQVRDMGLYEKCFILVGVGP
LASARAASWIRSNVPGVHIPDDVIKRLEGAEKQKTEGKRLCVDLIQQIREIEGVSGIHLM
AYRQEESVAEIIEESGALKGRAPHAVHPVIPDYMQQRYKVQA
>A0A5C7X1P9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp|TrEMBL
MDRLRRTGGERVPFSVEFYPPRDEAAEARLWRAARSFGQLNPAFVSVTYGAGGSTRDRTV
RIVGQLAEETTLLPVAHLTAVSHSVDELRSLVGAFADRGITNLLALRGDPEGGVHNEWVR
HPEGLEYAVELVELIRGLGDFRVGVASFPEGHPRAVDIEADTANLIAKLRAGAEYSITQM
FFDTDGYLRLRDRVVAADPEQGAKPIIPGLMPITSLRTVRRQVELSGSQIPPALLERLTR
AAGPGPEENRDEVRKIGIELATEMSLRLIAEGVPCLHFCTLNFAGATSEVLANLGMTVAV
>A0A8C1H825|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cyprinus carpio|TrEMBL
MVNQRADVGWQSSKSDSSGVSNSGESSKESSRCSTPVQDADRTDRLRDKMKRRIESGDHW
FSLEFFPPRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCNQTKEKITAHLNKAKRLGLKNIMALRGGMNGDFVPGRGRTQSLRNLPS
DSNIRNAWLNSIFNEVSAQIELHFFTDTFVNKTQVDAGFAERLRFKSNAVRLYQIRQEWY
GDFFCVNLVTFRRPLPWAVSAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNS
SSPAFGELTDYYLFYLKSKSPKEALLQMWGEELMNEESVYEVFTNYITGQTNPSGHKVMC
LPWNDDPLAPETNLLKDELEKVNCRGVLTINSQPNINGKPSSDPIVGWGPAGGYVFQKAY
LEFFTSSENVTALLQVLKKYEPRVNYHIVNVQGKNITNAHEMQPNAVTWGIFPGREIIQP
TVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLINLVDNDFPLDSCL
WQVIEDMFTLLDSPPETQEEGSQS
>A0A7X7MT78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentisphaerae bacterium|TrEMBL
MTFFEKLQSGRPTVSFEFFPPKTPEGWARLYATLAETARLDVDFVSVTYGAGGSTRENTV
DLVASLQNNLALHAMAHLTCLGHSQVDLSKILDRLAAKNVPAIMALRGDPPQGESSFRPH
PYGFSHASDLIGFIRDGWPQFKI
>A0A8J4TZU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clarias magur|TrEMBL
MVNQREENGWQPCKNDSSGASNSGESSKESSRCSTPVGEADHGHRLRDKMRRRIESGDRW
FSLEFFPPRTAGGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNY
CGLESVLHLTCCKQTKDKLTAHLSKAKHLGLKNIMALRGDPVGADWEEEEGGFNYAVDLV
KHIRSEFDDYFDICVAGYPTGHPEAESYEEDLKHLKEKVDAGAHFVVTQLFFRAETFLKF
LKDCRAIGITCPILPGIFPLQGYHSLRQLVKLSKLEVPEEIMKVIEPIKDNDDAIRNYGI
QQAVEMCKVLLDSGDVHGLHFYTLNREVAITEVLRQLGLWIEDPRRPLPWAVSAHPKRQM
EDVRPIFWSTRSKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLK
MWGEELTSEQSVYEVFTNYITAQPNQNGHKVICLPWNDDPLAPETNMLKDELEKINRKGI
LTINSQPNINGKPSSDPVVGWGPPGGYVFQKAYLEFFTSSENANALLKVLKKYEPRVNYH
IVNVKGENITNAPDMKPNAVTWGIFPGREIVQPTVVDPVSFMYWK
>A0A3A6H2S2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lachnospiraceae bacterium TF09-5|TrEMBL
MIKDLFAEKKQLLSFEVFPPKKEDEFANAFAVLDSLAVLQPDFISVTYGAGGSKSKKTVE
IASYIQNQLHIMALAHMTCVGSKKEDIDAVTAQLKEVHVNHVLALRGDRPSYMSDEQFDS
RHFSHAADLITYLKGETDLHIAGACYPEKHYEAADLESDLLHLKEKCDAGAEFLITQLFF
DNEAFYKFLEKSRNAGITLPICAGIMPITSAKQLGTTVSLSGSAVPKQLADIIATYGDNP
ADMRKAGIDYAIRQILDLKAHHADGIHIYTMNKPKVAQEIVSAIR
>A0A4U0ZV52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulforhopalus sp. IMCC35007|TrEMBL
MKSGSNLEKVLAAGHFSVTAECGPPRGADPEIVRKKAAFVRGHVDACNVTDNQTAMVRMS
SLAGCMLIKEQGIEPLIQMVVRDRNRIALQSDLLGASALGVRNLLCLSGDHQKFGDDPQA
KNVFDIDSMQLIHLVRTMRDEGVFPSGDKLEGAPQFFIGCAVNPFADPFEIRVPRLKLKI
DAGADFVQTQCIYNMDKFKKYMEDARKEGLHEKVKILAGVTPLKSAGMAKFMRRMVAGMD
IPEAVIERIAAEPKDKQAAKGIEMCIEQIEELKEVEGVAGVHVMAIEWEEKLEEIIGGAG
LLPRPVLV
>A0A2N2DF53|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-14|TrEMBL
MMESGNFAVTGEIGPPKSCNGEIVRHHAKMLKGWCESFNLTDNQTAIVRLSSIGAGQLLL
EEGLEPNIQIVCRDRNRIAIQSDVLGASALGMKNILCLSGDHQKFGNHPTSKNVYDVDSI
QLIKILDGMRNGYFANGEEMKDEPPKIYIGCAANPFADPFEFRVTRLEKKADAGADFCQT
QCILDMERFEKWMELVRARGLHKRIKILGGITPMKSVKAARYMKKFVAGMMVSDDLIERL
DKAEDVKAEGVQIAIEQIEHLKKMEGIAGVHIMAIAWEEIVPEICKRAGLAPRPQV
>A0A495EP57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter oryzae|TrEMBL
MFPTRIEIIPSEGIVAQVQAVVPLTTALTVTCLPHHGIERTMRAARQLSGLGYRVIPHLA
ARSLHGRAELTGILRDCNVAGIGEVFVIGGDRKQQAGPYESALPLLEDIAQYSGGVMRAG
IAGYPEGHPSVGALDLVDALVAKQHLATYVVTQMCFDAPKILDYVAFLRREGVQLPVWAG
VAGSVPRAKLVSLATQIGVGSSLKFISRKGPLARKLLSGDRYAPSALISELAEHPDRVSG
IHFYSFNDLAGATGGATISCRPAAAGLTSIPGAAQ
>A0A2K2RNB9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. DH-12|TrEMBL
MALGTASTRTDRARTVRDMLATGRTTYSFEFWAPKTEKGERNLWNALRRIEAVAPSFVSV
TYGAGGSTRAGTVKATERIAADTTLTPVAHLTAVEHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVRLIKESGDFCVGVAAFPEMHPRSSDWDTDVARFVD
KCRAGADYAITQMFFRPESYLRLRDRVDAAGCETPVIPEVMPVTSVKMLERLPKLSNAAF
PDALKERILAAKDDPAAVRSIGIDFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLG
LHHPPQT
>A0A0Q9AF83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. Root265|TrEMBL
MDYGPCGGVLPDGGCEMRPGRCAFSDVVPWTGVPAEPRPVNAPRVLTDFSCTPFDRREVQ
ATAAILASSCDAVLVGEHQNKPDFPPTLMGSLLLECGIDPWITLSCRDRNRVVLEQELRG
LSSVGIRTVFCVTGDGRGYDVRPEVTQTFDLDGPRLVALAASLGMTPGVPETPTAPPVHG
RPTRLVHKQHAGAQLAVLNHVPSPTIIAAFMAAARSAGLRIPVVAAVAVFTDHVSAAVLQ
GLPGLELDPQVTETVLTADDPVEAGIAAAVTEARALLAIEGVEGVNVSGLASASGPRAGA
EIKAEVGRRIRVDRDE
>A0A3N0CKH4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter oryzae|TrEMBL
MTSLEKNINDMATQISLEITPQDALTFASTAESLPCLTRVYITAIPGSDLFGLVAASEKI
RKTGMTPVPHIPARSISSREELESLLTNLSQVGVADLLLLAGSAPQPAGEFASSIDVLKS
GIVQSVGFKRVDVAGHPEGSPDVPSSELISALLTKQSWAKDTGIEMAIVTQFAFTGDAYI
SWLKDIRASGVELPVIFGLPGLAKISTLIRYGLKCGIGPSLRVFRKQAGSMLKLATGSYS
PDPIIVGLAEGLDDDEISNQRVGLHVFPFGALRSSVRYLATLNAGRFAVDSDGTIRTTED
AGLARRDV
>A0A561TXC8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces brevispora|TrEMBL
MDSLSTASAPAVGPLLEDFSLEMTGKDVPRLEEARDRIPAGTRINVTFLGNEDLGVRLAA
ARAVRQLGYTPVPHISARRLRSRSELEELLAAFRADGTADNVLVIGGDPATPHGPYDDSL
ALIRSGLLQSYGVRHVGIGGYPEGHPSIAGQVLWSAIEDKTTALAGQGLSGDVITQFGFD
ADPVLAWVESLRKRGIDAPVRVGVPGPAGIKRLMTYAARFGVGTSASIAKKYGFSLTNLM
GTAGPDRFIRALADGYDARRHGVLKLHFYTFGGIGATSRWVTEFLAVEGN
>A0A5B7FUY1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Portunus trituberculatus|TrEMBL
MHEPEYLSGYHSLKEKIQSRIESKDKFFSLEFFPPRTKGGAVNLLARFDRLREGDPLFCD
VTWHPAGNPGGDTETSSLTIAGAALNYCGLETMLHMTCCSMTKSEISHHLQRAKEVGIRN
ILALRGDPPMGHDDWVAPEDGFSYAADLIRHIRKEFGQYFVLCVAGYPSGHPEAASYEDD
LHHLKEKVDAGANFIITQLFFKAQAFIKFVTDCRAIGIECPIIPGIMPIQSYDSLRHIVN
LSKLDVPQDIIDVVTPLKGNDEAIRNYGIHQTTTLIKELFRADMAPGVHFYTLNR
>A0A2R6DC68|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halobacteriales archaeon QH_10_70_21|TrEMBL
MSTETRTLEELDGAGKLLDGARFELMPFESFEEEIRELPDGATVAVTTSPQLGIDATVER
TEQAAEQGFDVAPHVAARYVSDRDHLDEIATRLDDAGVTDVFVPGGDREEPAGEFESAYD
LLVALEELGHSFEEVGITGYPEGHEFLDDATLTDAMAQKEPYATYIVTQLCYDPAAVLRW
IDDIRADGVELPVEVGIPGVMNYQRLMQISQKVGVGDSIKFLRKTTGVLGFVKQLVGSRG
VYEPDDLVDGLAPYVDDDHYNLRGIHIYTFNQTPDTESWRAERLG
>A0A7R6VBS3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitratiruptor sp. YY08-13|TrEMBL
MFEELIEKLRSGTYITLETTPGHLPTINNILSKLDELALYKKVDAFTTTDNPLAKLKYNA
ILAAIKLQQRFNKPVIATMSMRDRNKIALQSDLLGANDFDIRAILALTGDPAKISDQPNT
KGCFEGDSTLLLDIIRFFNAGIDYAGKEFKIKPKRIYPFAVSNAYAKNPNTLLKKFKKKI
EHGAVGVITQPVFDIENLKNLLALFEEARNNFENERAKSELIVGFFPITRLKTAQFLASH
VPGINVPRSWIDELYKAHKDGEEKEYEVGFALSKELFTNIMALHPKVHIMTANRFDLAHA
ILS
>A0A736TAB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Salmonella enterica subsp. enterica serovar Choleraesuis|TrEMBL
MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGD
LSPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFE
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A7C4AE44|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MPLFSPRRYQAPFMPVQRDSLPVRVFTAFEQAIKGTLFGCRMCGNCILQETAFVCPMTCP
KGLRNGLCGGATPDHCEVDPTRPCTWYVIYHRAERMGRLDKLLEINAPVDGNRAGHETWL
DMIKFWFKRKAGPYPWDFVLNRAKFSREWDAFFYALRQPDWWQGDSQYHPPAYSEPISLL
EANLRSGVFTVTAEIAPPLDASPEGLIKKVNMLKPYVTAANFTDNASATCRMNSLASSKL
CLDAGLEPVMQLQARDRTRVVIQSDAVGASGLGIRNILCLTGDHHRFGPAPMSMPDQFDM
DGVQILWMLRRMRDEGKYIDGREMKARPKFFLGAAASPFGAPPKYEAIRAEKKINAGAQF
IQTQPIFDYGRFTEWLEALDKRNLLGKVHILAGIVPLRSAKAAHYMTEVPGVVLTESDLK
RMDAAGDKEAQAEMGVTIALEMIERLKNTPGIHGLHIMAVHWESIVPRLIEEAGLPRPVV
RELPRPEVVREKQEAVPAS
>A0A7W2AT13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MSWELAGATILEVVPPTRESGEEGFSKRMKRVEKLLSDGQFDAVNVPEIHDEENRDSRGE
RKHKFSTRVDSRVFGCKIREEFGLPIIVNHVVAHDPLDRQILWLHETVREYGIHDLVLVG
APHDRHPWPGPTVSEANEAFKAEFSDSHLRLGNICIPGRPGSPIPESERMAAKIRAGADF
FTTQILFSLNEITQLWREFESTRPDLLATPLLISLCPVRKAENLAFLRYLGVHVPEEVES
TLKSAAPAECLELSLQILCRLQEQMIETARNYEDLASPGWNIAPVGSIPGAAVLDLIRRL
PASLSR
>A0A521GWE9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MEGQQPPSPRRVGGCCVLSLIHRDRKPLLQALAEDVLVLDGAMGTELYSRGLSFQDCFDA
ANLDRPQWVLEIHRSYLDAGAQGVTANTFGANRFRLIRFRRERDLPSILERGAELARAAA
GAQRYVLGSVGPTGAEIEPIGRIARAEARAAFREVAAILDPLVDAFALETFNNIEEIVEA
LRGVREASDKPVFAYVTVDSQGLTLHGTRAEVCAARLDQAGADVIGLNCSTGPKTIVDAL
PRLVEATGKPLAARPNAGMPREVDGRVFYESTPDYFARFARRFLQAGGRVLGGCCGTTPE
HIRALHRAARAIGVQVREAAPAPHPPAEPPRPRPHTPLPLAQRSRLGQALATRAFPMSVE
LVPPRTPDMSAVLEAAKVVRDAGATVINIPDGPRASARVSNFAAAVILERELGVETLLHF
CCRDRNLLGMQSDLMGAAALNLRNLLVVTGDPPYVGNYPNVTAVFDVDSIGLCNIVDNLN
HGLDLGGNEFGAQTHFCFGAAFNHTALELERELQRFGWKVQAGIDFAITQPVFDASRFLE
VLARLPAARPPLLAGIWPLRSLRNAEFLATEVPGVRVPEPLLERMRAADRAGRAAEEGVR
IAIETVEALAGAVQGFQIAAPFNKPQPALAVLEAARACVPAASRT
>A0A7X8UN09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MTEPVSNLQSQLDSGKFVVTGEIGPPKGVNVDKCLHEAEAYLKNSVAAVNVTDIQTAVMR
TGSMAVSHLLVSKGIEPVYQMVTRDRNRLALQSDLLSAYVLGVRNVLALTGDHVAMGDHP
AAKPVYDLDSVSLLAAITNLEAGRDMGLDTKGNPNQLDGAPRFFKGACVTPCAEEVEPQI
IKLEKKIEAGAQFIQTQAVYDPAAFEKFMNRISHLKAPVLVGIVMLKTAGMAKYMNSSVP
GVNVPDAIIKRMADAAKEDRQKVSIEICGELVAKMKHCCQGAHLMTLGWDHCVPEIVKAA
GL
>A0A0D2X566|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsaspora owczarzaki (strain ATCC 30864)|TrEMBL
MTKSKTSTRLMSGSRFDRLSQGNPLFIDVTWGAGGGDPTAIELPTSSMTVASTALNLCGL
ETMLHMTCANQTKAQLTETLQRAKNNGIRNILTLRGDPAPGEGWKTIENGFGYATDLVKH
VRDTFGDYFGICVAGYPNGHPEAKSLESDLQHLKEKVDAGAEFIITQLFFDVETFFEFVR
KCRAIGIKVPIIPGVLPIQGYSSLRNLVKLSNLQPPQYILDTIEPIKDDDEAIRRYGVHL
ATNMCRELLDRVDEFGNRMIQGVHFYTLNREVAVREILLQLGLWSEGPRSLPWKTSANER
RSSEDVRPIFWSCRPKSYLLRTQEWDDFPNGRWGDSSSPAFGELTDYYLFHLQDTDDTAR
KEMWGRSCESIADIITVFTNYLSGKGNVQRLPWNEEPIAPETRTVLGPLIRLNERGVLTI
NSQPRVNGLRSDDPTHGWGGPRGYVYQKAYLEFFIASDRLPNLLRAIDAFPSVQYHAVNY
SGTEDLRNLENETPTAVTWGVFPGKEIVQPTVVDPISFGVWKDEAFALWKTQWGSLYPPE
SPSRKFLSEVHDTFYLVNLVDNDFVAGNIYDVFDMLFELEDAAAVPTQVYATA
>A0A6N7P9A8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sp. SYP-B3965|TrEMBL
MKVTEHISQAKDTLISFEILPPLKGKSIESIYDHLDPLMEFKPSFINVTYHRSEHMFKKR
ADGSFDKVEIRKRPGTVGICAAIMNHYQVDAVPHLICGGFSKEETENALIDLNFLGIDNV
LVLRGDAPKNETFFEAHPNGHRYAIDLLHQVVQMNNGIYLEEDLMGGLKTKFCIGVAAYP
EKHFEAPNMQTDMMYLQRKVEAGADYIVTQMFFDNKKYFDFVAKCREAGITIPIIPGLKP
LTTKKQMTILPRTFHVDMPEDLYTEVNKCKTDKDVELVGTEWLIQQSKELKAAGSPVLHY
YTLGKPHVVRKVVETIM
>A0A7C4V5D6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anaerolineae bacterium|TrEMBL
MSGDNGKELVVGSKLERLLKAGHFVVTGELGPPQNADRSVIEKKAGYLRDAVDAVNITDN
QTAVVRMCSMAVAKMLIDLGIEPIMQMTCRDRNRIAIQSDLLGAYALGVRNLLCLTGDHQ
SFGNHPQAKNVHDLDSITLIQMVRQMRDAKKFQCGEEIKGQEPRFFIGGAINPFADPFDF
RPFRLAKKVKAGVEFVQSQLIFNVPKFREYMKRCGDLGLLDKVYILAGVGPIKSLAAARY
MATSVPGMDVPQEYIDRMANAVKGIPQEDKKARREAWEREGIKICAEIIQQVKEIPGVAG
VHIMAIEWESAVPEIVKEAGLLPRPKLEA
>A0A8H3ITN7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Imshaugia aleurites|TrEMBL
MHIKDKLAEAERSRKPVFSFEFFPPKTAQGVQNLYDRMDRMHDLGPAFVDVTWGAGGSRS
ELTCEMVNTAQTIYGLETCMHLTCTDMEKQKVDDALKSAYSAGCSNILALRGDPPRENEK
WQAVEGGFQYAQDLVKYIKARYGDHFDIGVAGYPEGCDDQRDQEILMKHLKEKVDVGGTF
IVTQMFYDVEIFLSWVEKVRAYGITVPIVPGIMPIQTHAAFLRRATWSKCHIPQKWLDAL
EPIKNDDAQVREAGKGLVAEMCRKIIDAGIMQLHFYTMNLAQATRMVLEELDLVPKDGTP
TNRVLPWRQSLGLNRREEDVRPIFWKNRNKSYVARTQDWDEFPNGRWGDARSPAFGELDA
YDSGLKGTNEQNMKLWGKPESLRDVANLFVRFLEGKLQSLPWSEAAVTSEAETIRSELIS
LNRRGLLTITSQPSVNGVKSTHPVHGWGPKGGYVYQKAYIELLISPQLISELIARIERQA
NMTYYAVTKDGSLRTNAPSESPNAVTWGVFPGKEIVQPTIVETLSFLAWKDEAYHLGTDW
AKCYPASSASRQLIESIMNTWYLVNIVDNDFHQTHAIFSLFENLEVEDLDKPAMNDHRSN
GFHSPIANGEVHK
>A0A2A5GVE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Zetaproteobacteria bacterium|TrEMBL
MSKATFSFEFFPPKTEKAADKLWGCVAELVKLDPKFMTVTYGAGGTTRDGTIDTIAKKME
MTNIPIGSHLTFLNTTKDELYKYVDGLWERGVKHIVALRGDMPNDLEWPLAGDENYFQYT
SDFVEGLLARHPFEISVGAYPEKHPDSKTLNADVHALQLKCEAGATRALTQFFFDNDVYY
NFVEKCEKVNIRTQICPGLLPIHDFKSMCNFAKRCEANVPLWLHEKFEGLDDKPEEARKV
AIDLLVKQSEDLVKNGVEHIHYYTLNKSDITTQAVDAIS
>A0A3D5M1F4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
MTWELEGATILEVVPPTLSSGDEGLQKRLRRVERLLASNAFDAINIPEIHDEDSRDSRGV
RTRGFSSRLDGRILARHIRQQFQLPVIINHVVAHDPLEHQLNWLNETVGDYDIRDIVLVG
APHDRFAWPGPSVSEANQAFKSQMASSGIRIGNICIPERPGSPIPETERMAAKVSAGADF
FTTQIVFSPHEITQLWKSMSKDQPELLSTPLLISLCPVKKASNLAFLRYLGVQVPDIVET
VLSEVPHGDCLDRSLEILCSLQDDLIQHTSGIPNLAIPGWNIAPVGSIPSSAVLDLMERL
PSSVST
>A0A2P0AYB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Citromicrobium sp. RCC1897|TrEMBL
MFDPAREADYATTPPLFSGLPGDIDVSFEFFPPKTEKMEASLWNAIEELKPLDPHFVSVT
YGAGGSTRERTHKTVARIIAEAGLPAAAHLTCVNASKKETQRIAEHYWEAGVRHIVALRG
DMPREDGMLGPFEPHPDGYANAEELVRGLKEVADFEISVSAYPECHPDAQSPQAEIDYLK
RKIDAGADRAITQFFFSPETFFAFLEKTDKAGIDVPIVPGILPITNVAKAREFAGQCGAE
IPQWMDNLFEGLDQRPAARQLVSATIAAEMCRRLYAGGIRHYHFYTLNRADLAYAICHLL
GMRPTENPA
>A0A3N5EAR3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium|TrEMBL
TALNLDEELRRFAYKVEAGAEFAITAPVFDLRAFEVFLARVEGFGIPVVAGLWPFDSQLN
AEFMANEVPGVSVPEALLERMRRAGDAAGAACEGVAIAREIANGLRGRVQGFQLGNATGR
VDGVLEVFES
>A0A2D7X2V9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Marinobacter sp|TrEMBL
MQSQKQFKRRFSFEFFPPKTDQGKEKLQNVRNQLAEVNPDFFSVTFGAGGSTRDRTIETV
LNLHSQGISTAPHLSCVGGTRQEIGELLDLYREHGINRIVALRGDMPSGMGAAGELRYAN
ELVEFIREHSGDTFNLEVAAYPEFHPQARNAEEDLKNFARKVQAGANSAITQYFFNADSY
FYFIDRLEKMGVTIPVVPGIMPIVNFSNLVRFSDMCGAEIPRWIRKQLEAYGDDRESIRK
FGEEVVTEMCEKLLAAGAPGLHFYTLNQVEPSISIWKNLGISEREKIAX
>A0A1M7IMS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga sp. CF418|TrEMBL
MKVTEHIAQAKDTLISFEILPPLKGKSIDSIYEHLDPLMEFKPAFINVTYHRSEHMFKKR
ADGTFEKVEIRKRPGTVAICAALMNHYDVDAVPHLICGGFSREETENALIDLNFLGVDNV
LVLRGDAPKNETFFEPEPHGHRYADELLQQVVHMNNGIYLEEDLQGGVKTSFCIGVAGYP
EKHFEAPNMQTDMSYLKKKVENGADYIVTQMFFDNQKFIDFVAKCREAGITVPIVPGLKP
ITTRKQLTVLPRTFHVDIPADLANEILKCKTDKEVEAVGTEWLIQQSKELKAFGVPVLHY
YTLGKPNVIRKAVEAVV
>A0A3D6CEV7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVTDHINQSGNKTLLSFEILPPLKGKGIQSLYQHLDPLMEFKPSFINVTYHRREHTFKK
RADGRFEKVVIRKRPGTESICAAIMNKYNVDTVPHLICGGFSVNETEDALINLNYLGIDN
VLVLRGDAAKNESAFEAEPDGHAYAIDLLQQVTNLNAGIYLEEDLKNTTRTRFCIGVAGY
PEKHFEAPNMESDL
>A0A4Q3SVF8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophagaceae bacterium|TrEMBL
MKVIDHINQSTKPLVSFEILPPLKGKGIQSLYNHLDPLMEFKPAFINVTYHRSEHVFKKK
ADGTFEKVVVRKRPGTESICAAIMNKYNVDTVPHLICGGFGINETEDALINLNYLGIDNV
LVLRGDAAKNEAGFEPEPGGHKYALELLRQVSNLNSGVYLEEELKNTTKTKFCIGVAGYP
EKHFEAPNMDTDLQYLKQKVDAGADYIVTQMFFDNSKYFAFVNACRAIGIEVPIIPGLKP
IYTKKQLTVLPKIFHIDLPTDLSNEIVKCKDDEAVEQVGTEWLLMQSKELYKAGVPVLHY
YTLGRPNLVANVVRELV
>A0A434EKC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M6A.T.Ca.TU.002.02.2.1|TrEMBL
MNQFRFSRRPDIGDKIRVSFEFFPPKSDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETALTPAAHMTCVNAARHEVDEVIQEFAEMGVTRFVALRGDPAEGVGA
AYRPHPDGYANGAELVGALKGVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRAGALVPAWLAERFD
GLQKDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHGAEAE
AAGSAAA
>A0A5C7WCX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas alcaligenes|TrEMBL
EKLMGVARQLAGYNPDFFSCTYGAGGSTRDRTLNTVLQLDGDVGVPTAPHLSCVGDSKDE
LRSLLSQYKNSGIKRIVALRGDLPSGMGMASGELRYANELVEFIRSETGDHFHIEVAAYP
EVHPQARSYEDDLQNFVRKCQAGADSAITQYFFSADCYFYFVERVRKLGVDLPIVPGIMP
ITNYSKLARFSDACGAEIPRWVRKQLEAYGDDLESIQAFGEQVVTEMCERLLQGGAPGLH
FYTLNQADASLAIWNNLKLPR
>A0A2E0R1M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobiales bacterium|TrEMBL
MHIQDILAERKPTFSFEFFPPKTAETSEALYSTISELESYEPAFVSVTYGAGGSTRELTN
DLVVRIKNSTSLDPIPHLTCVCHQESDIESILQRYAEEGVSNILALGGDPPRNLENYNRA
DDAFQHAADLVRYIKKFSEKGNHPDSRGFGIGVAGFPEGHPATPNRLKEMDYLKAKVDEG
ADYIVTQLFFSNDDFHDFRDRCELAGINVPIIAGIMPVVSTKGMERMADLAAGARFPAKL
LRALNRAGDDSEAVEKVGIHYATQQCSDLLENEVSGIHFYTLNKSHATREIYASLGLKTS
ASLVA
>A0A7K4HFK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MAKRPAYSNLVKTMKEGKFLFTGELEPKKMVDLSSILHSAEEMKKTGKITAANVTDGPQG
DAYTCSLVPCHLVQEKVGLETIWQMTVRDRNRIALFGDILGGAILGLRNLLALTGDHSAL
GDNKNARAVYDLDSTQLIDLVSKMVDDGTDLEGNEIEGGKIEMNVGCAANPNSNPREPEI
LKVGRKVEVGADFIQTQTSFDIDDAKEFLKDLEKFNIPVLLGLFPIKNYGIAWYFNEYIP
GVSVPKDLLSALKGVKKEFKEDKKKRNEAIDKINIDFFEPFIKEIQKTTKAAGIHCMAVH
YERLFEPLLKNF
>A0A868B1C0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serovar Bataviae|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESA
>A0A842TP00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MSEDRRVDRPAYSKLMKAIKKGEFVFSGELEPEKQTSIDDLIKSANAMKEYVLAANVTDG
PQSMAYACSLACSHLVQKKTGLETVYQMTVRDRNRIGLEADVLGASILGIRNILSLTGDH
TALGDTPGAKPVFDLDSAQFVHLMSKMIDEGTDFSGRKIHGQVKINVAVAANPNAVPREP
EIIKVERKVYCGADFIQTQTAFDIDQAKSFLKDLEYLNCPVLLGIFPLKNYGIANYFDKY
IPGVSVPKDLLADLKKTKKIDDKAKRKEKIDEINIEFFIPLINEIKKTTKAAGVHCMAVK
YERLFKPLLSRIK
>A0A7K3NQN9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfovibrio sulfodismutans|TrEMBL
MKIIDLIGSGKPFVSLEFFPPKEKSAWPGFFDVVNWLTPTNPLFVSVTYGAGGGTQANTL
EIVSRMKKEYGLEPMAHLTCVGASEKNIRAFLDSLVDSGVENVLALRGDPPKGQADFVPD
SEQFRHASDLVAFIRAEYPSLCIGVAAYPEMHPQAESPEKDLEYLGRKVDAGGDFIVTQL
FFDNRLYFDFVARARAAGIAVPMLPGVLPVISLAGAKRMLAFCGASMPPDYMAALEAADA
SGDSQAVAELGVAYATAQARELIAGGAPGVHLYTLNKAEACLKIIGGLGLPS
>A0A524F054|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MTELKTHSNLMKAIRSGEFVITGELEPERTSNIEPTVHEAIEIKKYCVAANVTDNPKSTV
CLSSLAGSYLTQEKSGLEIVYQLTCRDQNRMGLGAAILGANALGLKNILALTGDHNACGD
MPKSKPVFDYDSTHLVKLVREMADKRSIEGLALDDDCPDITIHVGGAANPNANPMGPEIM
HIQRKAMAGVEFLQTQVVYDIDIAEPFLKEIKDKTGVPVLLGIFPMRGYGVAKGFDEMVP
GVSVPKDLLAKFKAVKKSGFEKKEKNEAYRKLNIDFYVPMLKELKKKNLVAGCHIMAVHY
PKIFPPLLDALGLQPR
>A0A7K4GP58|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Lokiarchaeota archaeon|TrEMBL
MTEVKTYSKLGEAIAKGEFILTGELEPEKTTDLSHTIHEAKEMAPYVIAANVTDSPLGIV
TINSMAATHLIQKAAGLECVWQMTVRDVNKLGIAGMIMGAHALGIRNVLSLTGDHTALGD
MPESKPVFDLDSATLVKLVREMVDKGTINGNEIEAPPTLHVGAAANPNAEPMGAEILKIG
RKAEAGCEFIQTQVVYDLDRTIEFLTEIKKYKVPILLGIFPMKSYGMAKGFDTFVPGVSV
PKEILAKWKSVKKEVTDKKQQKELYDQYNYEFFKPFITELRKKDLLAGIHCMAVHYPRIF
PKLKDIIGN
>A0A4R9A364|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. Hh11|TrEMBL
MSACNARPAFSFEVYPPKSAAAASALMSTIDHLAAAGPEFISVTYGANGSSRNSSLDVLR
YIKNHTEADAMAHLTCVGSSHAEASRLIREFLDAGIRSFLAIRGDAPQGAVEGDNTFLGD
LHSAGELVQLIHRVQTERVPYIETVIPGLPGARGVKTERSKVRIGVAAFPNGHPNSRSVS
QDIDTLLAKQAAGANLAITQLFFHADDYLSFIQRARSAGVLFPILPGIMPVTSPNRLRRI
LQLSGEKLPADLSIDLEVEPTEEGQRQIGIDYAVRLGQDVLAGGAPGLHLYAFNQHDTVL
QVLEGCGALPVPAVML
>A0A208Y603|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pigmentiphaga sp. NML030171|TrEMBL
MSSSVFPDAAPADAAPVFSLEFFPPRDTPAQERLVRTAKQLQGLHPHFASVTFGAGGSTR
DGTMLAVSMLQKLGYETAPHLSCIGSTPESLREILHTYRQAGIRRLVALRGDMPSGMGDM
GELRYARDLVDFIRKETGDWFHIEVAAYPEMHPQAQGPEADLDRFVEKMRAGANSAITQY
FFNADAYFDFVDRATAKGVLAPIVPGIMPITNYTQLARFSDMCGAEIPRWIRLRLASYGD
DRASIRAFGHDVVVELCQTLLDGGAPGLHFYTMNQADATQAVWEELER
>A0A4Q5P954|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MNAALKLPVSFEFFPPKTPEGAAKLRTVRQALYSQAPEFCSVTFGAGGSTQEGTFTTVSE
ILAEGVGAASHFSCIGATKARVREQLAELKGMGVKRLVALRGDLPSGYGAGGEFHYASDL
VAFIREEMNDDFRIEVACYPEVHPQARSPEADLNAFAAKVRAGAHSAITQYFYNGDAYFR
FVEDADRLGLEIPIVPGVMPIISSTQLMRFSDACGAEIPRWIRLRLQAYGDDTASIKAFG
LDVVTDLCEQLRAGGAPGIHFYTMNQSAATLEICQRLAQ
>A0A2W4QH85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methylumidiphilus alinenensis|TrEMBL
MDSQKHHPRNFSFEFFPPKTEQAIANLRGTVAKLAELKPSFCSVTFGAGGSTREMTYETV
VEIQETTGIEAAPHISCIASTRDNISEVLQAYQAKGIRHIVALRGDMPSGMMSAGEFRYA
NELVEFIRNETGDHFHIEVAAYPEVHPQAPNLDADLRNFKRKVEAGADTAITQYFYNPGA
YFRFVSDCEKLGIDLPIVPGIMPITNYTQLSRFSEACGAEIPRWIRKRLEAFGDDRESIR
AFGVEVVTILCERLLEQGAPGLHFYTLNQSEACLAIWENLGLSGQS
>A0A146G8Y2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrimicrobium sacchariphilum|TrEMBL
MHIEDTLRESETTFSFEFFPPKTPEASENLYQTIRELEAYRPDFVSVTYGAGGSTRDLTH
DLVLRIKRTTSLNPVPHLTCVCHTEAEIESILARYAEEGVGNILALAGDPPVREGYDRSR
DAFQHAADLVGFISRFNASGKHADPRGFGIGVAGFPEGHPATPNRLLEMDYLKAKVDAGA
NYIVTQLFFDNRDFLDFRDRCSLAGINIPIIAGIMPITSLGGMRRMAELAAGARFPAKLL
RALQRGQNDPAAVERIGVHYATEQCADLLENNVRGIHFYTLNRSDATRRIFDNLGLRSVK
A
>A0A0N1DQ41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium acidisoli|TrEMBL
MALNNEARGRNIGISFEFFPPKSEEMEGQLWDTVSKLQDWDPDFVSVTYGAGGTTKAPTL
TAVTRFLSQTPLATASHLTCVGATKEETHQMIETFRKVGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKAVGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLEKVRAAGVSIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAADVAAEQIEDLVRRGINEFHLYTMNRAPLVSAVLDNLGFSRRAAKSAGAAA
>A0A523QBH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ideonella sp. MAG2|TrEMBL
MSERQAPISFEFFPPNTPVGSEKLKTVVKDLSVVNPEFFSVTYGAGGATREKTLATVQDI
ATLGYEAAPHLSCVGSTREGIAEILQTYRAQGIHRLVALRGDLPSGTAVAGEFRYASELV
RFIRETQGEDWHIEVAAYPEYHPQQRYAARDLQHFAEKMKAGANAAITQFFFNPDAYFHF
VDEVRKLGVTAPIVPGIMPIHNYARIAQFAQRDGIEIPRWVALKMEGFMDDAASVRAFGL
DVVTRLCERLLADGAPGIHFYTLNQSALSLEICNRLGR
>A0A486XF83|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Avibacterium sp|TrEMBL
MSYAKEIDTLNNHLSGINGDINVSFEFFPLKNENMEKILWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSVVKHIKQETGLEAAPHLTGIDATPEELKKIAQDYWDSGIRRIVALRGDEP
AGYDKKPFYASDLVELLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVIT
QFFFDIDSYLRFRDRCASIGIDAEIVPGILPVTNFKQLQKMAAITNVKIPAWMAKMYEGL
ENDQTTRNLVAASIAMDMVRVLSREGVKDFHFYTLNRSELTYAICHMLGVRPE
>A0A1H9BUE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solimonas aquatica|TrEMBL
MTSHASRLTAHDLSFSFELFPPRTPEGAAKLPAVVEKLATLSPSFFSVTYGAGGSDQDGT
YETVVSVIKQTGIAAAPHLTCVGSTREKIAALLARYRAAGIRRIVALRGDLPATALSSEA
PGEFRYASELVSFIRESHGDFFSLEVAAYPEMHPQAASPEADFEAFRHKVECGASGAVTQ
YFYNADAYFDFCERCARANLALPIVPGIMPITNYAQLMRFSAGCGAEIPRWVRLRLEQLQ
NDKPALLDFGLDVVARLGETLLKQGAPGLHFYTLNQAEATLRLWQRLNLPLPIA
>A0A4Q3LIC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MMLPISLEFFPPKTPEGADKLRAVRQQLYALKPEFCSVTYGAGGSTHAGTFTTVSEILAE
GVDAASHFSCIGATRARVRDQLAQLQAMGVKRLVALRGDLPSGYGIGGEFQYASELVEFI
RAETGRAFRIEVACYPETHPQAKSPQADLQAFVAKVRAGADAAITQYFYNADSYFRFVDE
ARKLGADVPVVPGIMPITNSSQLLRFSDACGAEVPRWVRLRLQAFGDDAASIKAFGHEVV
ASLCERLVRGGAPALHFYTMNQAQATSALCGALK
>A0A3A4R9X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium|TrEMBL
MSLPISLEFFPTKTPEGAVKLRAVRQQLYALKPEFCSVTFGAGGSTQDGTLQAVTEIMAE
GCPAAPHLSCIGQSRESIRERLAAYSAAGIRRIVALRGDLPSGYGVGGEFRYASDLVAFV
RAETGDRFHIEVAAYPETHPQAKSPLADLDAFAAKVKAGANSGITQYFFNSDAYFRYVDD
LHAMGVDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRMRLQAYGDDTASIKAFGLDVV
TDLCDQLRHAGVPGLHFYTMNQSVATMDIVQRLQLA
>A0A143Q822|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodococcus sp. PBTS 1|TrEMBL
MHVTDRSRTSRTPSVVDRLAAATHGSVPFSVEFSPPRDQAGEDRLWRTVRAFEQMHPAFV
SMTYGAGGSTRDRTVRVTGDLADSTTLVPVAHLTAVGHSVAELRSMVGAYADRGIANILV
LRGDPPGDPLGPWEKHPDGVEYAEDLVRLVKDLGDFHVGVASFPGGHHRSPSLDDDTRFL
VGKLRAGADYSITQMFWDVEDYLRLRDRVSAFDPEQGAKPIIPEIMPITSLRSIDRAVEL
SGSELPAAVRARLAAAAGTGEEDRAAVRAVGIELATEMGERLIAEGAPGLHFITLNFAKA
TSEVVANLGLARPAPAMTGSATGVESA
>A0A5C3LNA7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Coprinopsis marcescibilis|TrEMBL
MKLSHKIAAHDAAKPFYTFEFFPPRTDQGFENLIARISRLAALDPIAISVTWGAGGSTKD
QSLDLAGFTQSEYGLDTILHLTCTNMEQGLIDDVLKDVKDRGIHNLLALRGDPPRGEEEW
IPSDTRFTHAIDLVSYIRASPEYSSHFCIGVAAYPDGHTDGSLGEDEELDHLKAKVDAGA
DFIVTQLFYDVDRFLTWLQKVRAKGITVPVIPGIMPIQTYATFARLTKLSGTKIPPALET
DLLPIKNDDQLVKDYGVQYAAEMIKRLRIEGGIQGFHFCTLNLEKSVKRVLEHLEWTPVI
TTGRQNKLIADLPESLAQPADLDLLITPSSATNSATLGLGTIPALAEAGRGELNNAASWD
DFPNGRFGDFKSPAYGNQDPWGGLGISRTEALQHWGYPKTVDDLTKIFLAHLQSRIPQTP
FSPGPLDPESMTILPHLERLTKRGWWTVGSQPAVDGASSSNDVFGWGPRSGYVFQKGFVE
FFCDVGDVEAIQKRIDEKGGGWVYYFMANNKGESRSNVPDEGRNAVTWGVFPGQEVQQTT
IIEQESFLSWKDEAYSIWNDWANFYHPESPERKLLQTVADERWLVSVIHHDYKDPNALWT
FLLDGEA
>A0A800K2V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MFSPEFFSVTFGAGGSTKIKTLETVLDIKSSGNKAVPHISCISSSKKEIRDLLSEYKKHK
INHLIALRGDNPSGAVSNGEFKYANELISFIRDETGNDFHIQAAAYPEYHPEANSAKEDL
DNFKRKIESGADSAITQFFFNVDAYFKFIEECRKRSISIPIIPGIMPIYNIKQLSRFASN
CGAEI
>A0A7Y7NYA6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKIIDHLNKSKKTLFSFEIMPPLKGDSIHSLFEGIEPLMDFKPPFIDVTYHREEYIYKKH
ANGLLERRTVKKRPSTVGICAAIQNKYQVEAVPHIICGGFTREDTENALIDLHFLGIRNL
LLLRGDPIKTEKNFVNEADGHNYASDLIEQVSGLNNGIYLDNELQNHFPTNFCIGVAGYP
EKHFEAPNLKSDLKYLKMKVDKGAQYIVTQMFFDNNKFFQFVDLCRAEGIMVPIIPGLKP
ITTKSQVTALPKTFNIDLPEELADEVEKCKNNAEVCELGIEWSIQQSKELIEFGVPCIHF
FTMGKSTAVKQIAEKVF
>A0A7W2GRQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MPRIYSNRNKIGDDSAPISVSFEFFPPHSEQQVEILWNSVERLAPLAPTFVSVTYGAGGT
TRDRTHKTVSRIVKEANLRVAAHITCVGATCSEIDSVLDAYHEAGVTDIVALRGDAPDGV
GAAYRAHPGGYQLTADLVSAIKKRGHFEVAVSAYPEKHPESADIWADIEFLKRKVDAGAD
RAITQFFFDNDAFEVYLERVRRAGVTIPIIPGIVPVHNFKQVANFAARCGTHVPAWLHRR
FDGLENDPATRQLVAAAVAAEQVLDLVDRGISDFHFYTMNRADLVYAICHMLGVRGSALE
QAAA
>A0A7V0WLC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MNNSGLDFKNFEETRPGHTSRGRLERILRRGEFAVTAELNPPDSADPNEVFKRGAIFDGW
VDGINATDGSGANCHMSSVGICALLTRRGYAPIMQISCRDRNRIAIQGDVLGAAAMGVSN
ILCLTGDGVESGDQPGAKPVFDLDCMSLLETIRVMRDEGRFLSGREITYRPHLFLGAAIN
PFAPPYDFRPLRLAKKIEAGAQFVQSQYCFDIPMLKEYMNRVTDMGLHEKCFILIGVGPL
ASARAARWIRTNVPGIHIPDAVIARIEGARDQRQESKKICIEIMQQIKEMPGVSGVHVMA
YRQEELVSEVVHESGVLQGRKVAVGTELG
>A0A2G2ZKL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capsicum annuum|TrEMBL
MKVIEKIQESIKDDKVVFSFEFFPPKTEDGVDNLFERMERMVSHNPSFCDITWGAGGSTA
DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALENIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGLATPEAYEKDLAYLK
QKVDAGADLIVTQLFYDTDNFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK
IPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKIMASGIKTLHLYTLNMEKSALAILMNL
GFIEESKISRPLPWRRPTNVFRVKEDVRPIFWANRPKSYISRTIGWDEFPHGRWSNAQNP
SYGALSDYQFMRARSRDKKLQEEWAVALNSVEDIYERFMNYCLGKLRSCPWSELDGLQAE
TKIIDEHLSNINTKGFLTINSQPAVNGAKSDAPLVGWGGPGGYVYQKAYLEFFCSREKLT
TVVEKCKAFPFLTYMAVNKQGNFISNIHQIDVNAVTWGVFPAKEIVQPTIVDPVSFMVWK
DEAFEIWSRGWAQLYPENDPSRKLLEQVQNSYFLVSLVDNDYINGDLFAIFKDI
>A0A8C6NMB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nothobranchius furzeri|TrEMBL
VVSSDSSGTSNSGGESSKESSRCSTPVLDAVRSDRLRDKMRRRMESGDQWFSLEFFPPRT
ASGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLT
CCNQTKEKITGHLAKAKHLGLKNIMALRGDPVGSDWEEEEGGFNHAVDLVKHIRSEFDDY
FDVCVAGYPTGHPEAESYEDDLRHLKEKVDAGADFIITQLFFRADTFLTFVDDCRAIGVT
CPILPGIFPIQGYQSLRQLVKLSKLEVPEEITRVIEPIKDNDAAIRNYGIHQAVEMCRVL
LDSGKVPGLHFYTLNREVAPTEVLRQLGLWIEDPRRPLPWAVSAHPKRRVEDVRPIFWAS
RPKSYIYRTQDWDDFPNGRWGNSSSPAFGELNDYYLFYLKSKSSKEALLQMWGEELKREE
SVFEVFTCYITGQLNRNGHKVMCLPWNDEPLAPETNLLKDELEKVNRRGVLTINSQPNIN
GKPSTDAVVGWGPAGGYVFQKAYLEFFTSSENVNALLKVLKKYEPRVNYHIVNVHGRNLT
NAHEMQPNAVTWGIFPGREIVQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMII
KYIHDNYFLVNLVDNDFPLKSCLWQVLDDMFELLDAPLETLADGMPGDGSHGDGSHDNGT
LAE
>A0A1S8D705|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas mucosa|TrEMBL
MGRWLTGPRFGALPAPAALPAPALSFEFFPPRTEALENQLWSCIRRLEPLAPRFVSVTYG
AGGTTQARTHATVSRLVRETALTPAAHLTCVGASCGEVDDVARQYWDAGVRHIVALRGDP
PAGAPDYVPHPQGYAYAADLVEGLRRVAPFEISVAAYPETHPSARSAEADLDNLKRKIDA
GATRAITQYFFDTETFLRFIDRALAAGISVPIVPGIMPVSNFNQMRNFSARIGASVPDWM
AALFEGLDDDAETRRMVAAVVAAEQVRLLQANGVDEFHFYTLNRPDLTYAIAHILGVRPS
RPADPASESGVEEEGKAEAASRQAGQAGA
>A0A7C2LX90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MDRGKERRSRLLGDGDITVSFEFFPPKTEKMEEALWAAIRRLEPLAPRFVSVTYGAGGST
RERTHATVARLVRETSLTPAAHLTCVQATRDEVDEVARGYTAAGVRHIVALRGDPPTGVG
SRYSPHPGGYANAADLVAGLKRLSNFEVSVAGYPEKHPDSPSLQADLDNLKAKVDAGASR
IITQFFFDNAHFLRFLEAARAHGIWAPIVPGIVPIHNYKQVSGFASRCGASMPSWLARRF
DGLDADPQTTHLVAAAVAAEQVMDLVDQGIRQFHFYTLNRADLVYAICHLLGLRPQPAAA
REAVNA
>A0A522FSM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MAKTNILNRLKEGVVLFDGGMGTELYNRGVFINKCFEELNLTNPTLVRQVHEDYRKAGAE
VLETNTFGANRFKLKPFLLADKLYDLNYQGALIAREAGGNDVYVAGAVGPLNVRIEPLGP
ISREEAREYFKEQIQPLIDGGVDLLIFETFVYPEELKQAVIAAREICKLPVIAQMTIDED
GCSLTGAEPEVTIKELENLGADIVGVNCTVGPQVMLNWLERTRKHTSLPISIMPNAGKPK
NIDGRNIYLTSPEYLGEYAKHYIQSGANIIGGCCGTGPEHIKRMRNTLNSMKPQIAAPKI
EISKVEEFPDIEVIPMEKKSRLARRLFDKHFVKFVELVSPHGVSAHKEIEKAREMNYIGI
DVINIPDGPRASARMSALSLAVQFQRDVGIETVLHYVCRDRNVIGMQSDLLGAYALGLKN
ILAITGDPPKLGNYPDATGVFDVDAIGLVNILNRLNHGLDIAGNPIGKPSGFFIGVGANP
GAINLDEEIRRLDWKVEAGAEYIVTQPVFDVKIFEQFMNRIQHIKLPVIAGIWPLTSLRN
AEFMNNEIPGCSVPENIMKRLENVQDNKEASLAEGVKIARETLKSIMSFIRGVQISTPFG
RVQGVLDVLEGIDK
>A0A2N2BIR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium HGW-Firmicutes-3|TrEMBL
MMIKDYIKEQVLLMDGAMGTYFAELTEGHYTLSEPANISKPGLILDIHKAYIEAGAKLIR
TNTFAANPYTLYRSFDEVKKIIIAGIDIANEAVKGTDCYVAYSIGPIGEPYDIEDYEIES
TYRKLIDVGLLKNVKIILLETFSRIDQVNQLVEYIHEHGPNIQIMTNFTVNQHGYTKVGV
NKEKIIQQTRQQDLVTTYGFNCGIGASHLLSLIKTLDFDPSKMVAVPNAGYPDQQLERMV
YQSNADYFADTMIKICEEGVRIIGGCCGTTPEHIRKIRERLNALDFGEVKSISRMKRKTQ
PLKPLHNSFREKLEDNQFVVAVELDPPFKMDMSLIISSAHLLKEVGVDIITFADSPLGRT
RADALLIAAKIKQLTGMEVLPHVCLRDKNLIALRGGLVGAHLSDIRNILIVTGDPIPSDD
RDEVKSVFNMNAISFMQYVTEINSELDLDTFYIGGALNPYTQNMEVTLERVMKKKEAGAS
YLLTQPVYNDAGIQAIKKVRDETGMKILGGIMPLVSLRNARFLHYEFPGIIIPDDVMARF
DDEMTKEEAEKVGVELAVALATKMKPYVDGLYFMTPFNRATMIEKIIKKMDIR
>A0A350BX47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MKLTEYFKSDKTLFSFEVLPPLKGKSIDSLYKAIDPLMEFNPAFVDVTYHREEYIERPRK
DGGYDKISTKKRPGTVAICAAIMNKYKVEAVPHLICGGFSKDETENALIDLAFLGIENVL
ALRGDNLKNERNFVPEKDGNGNSLDLIRQIGDMNSGVYLDQELQNATETNFCIGAAGYPE
KHVDAANMQSDLKFLKRKVDAGAEFITTQMFFDNKKYFEYVDLCREAGIHVPIIPGIKPI
TKKIHLRALPSIFNMDIPEPLASELHDAKDDAAARQIGIEWCIQQCKELKAANVPALHFY
TMSFSSATKDVVSQIF
>A0A553DRK2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. ZT3R18|TrEMBL
MKVTQHIENAKGETLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKMGGNNFAVDLVSQINQLNCGKYLHDVMDVDNQADFCIGVAGY
PEKHLESPSLISDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVAKAREMGITVPIIPGIK
PIAIQRHLQILPQIFRIDLPEDLIHAVDKCKTNADIRQVGIEWAIQQSIELKAAGVPVLH
YYSMGKSENIRQIASKVF
>V6S338|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium enshiense DK69|TrEMBL
MKVTQHIEKANGKPLFSFEILPPLKGQNIQCIFDNIEPLMEFKPPFIDVTYHREEYEYKE
LPNGLLEKKVVKKRPGTVGICSAIQNKYQVDAIPHILCGGFTKEDTENFLIDMDFLGIDN
VVALRGDAVKSEIYFKPEKEGNTYASELVTQISNLNNGIYLDSDLQNTNKTDFCIGVAGY
PEKHMEAPSLDSDIYFLKQKIKNGADYIITQMFFDNQKFFDFVDKCRAAGITVPIIPGLK
PISTKKQLNLIPHRFKVDLPDDLIMEVVKAKDNEAVSQIGIEWCTAQSKELAKAGIPVLH
YYSMGKSDNIRQIASEVF
>A0A662BWI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
QSIYDTIDPLIEFDPKFVEVTYHREEVEFREHADGSIERKVLRKRPGTIGISAAIKFKYG
IEVIPHIICGGFNFEETENGLIDLHFLGINNLLVVRGDNLPGEKFFRATKGGHQYTSELI
RQIMDLNHGGYLDEELKNTTSTDFAVGVAGYPEKHAESPNIQTDIKHLKEKIDAGAEYIV
TQMFFDNSMYFDFVDRCRKAGITVPIIPGLKPISTKSQLGTLPRTFSISIPEELQLEIDK
CKGNKEARQVGVEWAIMQSKELVSKGAPVMHYFTMGKSDNIRQIAKAIF
>A0A2G1Z0R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sneathiella sp|TrEMBL
MSISGIAPSQNTASSLVTPGQANRVEVSFEFFPPTSEVLAEKHWQALSRLAPLGPKFVSV
TYGAGGSTRERTHALVSRIRQETDLEPAAHLTCVGATIEEIEGVAESYWNSGIKHIVALR
GDPPEGEDTFRPHLGGFNGSVELITHLKKMHDFEITVGCYPEIHPEAKSSLADIDYLKRK
MDAGATRAITQFFFDPDVYLRFVDRAQAHGITIPIVPGILPVTSYSKIRQFSGQCGTQVP
AWLTHLFETLDEDPATRNLVAAMVAAEQCKQLQRAGVTDFHFYTLNRADLVYSVCHTLGL
RPDQLVSSS
>A0A497CPA5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium|TrEMBL
MDKTVIEHIQQSDKTLFSFELLPPLKGHNFDGIQTAIDPLIEFKPSFINITYHQQEVIYE
TVSKDLMKKRTVRKRPGTVGISAAIKFRYGINVVPHIICGGFSKEDTENALIDLQFLGIN
NLLVVRGDPQPGTRVFTPEPNGNEHALDLIHQIADLNNAKYLDDSLENTRATNFCIGVAG
YPEKHSESPNMDSDLFFLKKKIKAGASYIVTQMFYDNKKYFDFVAMCRAEGITIPIIPGL
KPITTEQQIRSIPKTFNVDIPAALVKEIIKCKDNKQVRQLGIEWAIAQSKELMAQGVPVL
HYYTMGKSDNIRKIAEEVF
>A0A2A4R9K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MTHSRTLKSSISRRTLKGADFNVSFEFFPTSSDTAEASLWKSVRRLESLSPSFVSITYGA
GGSTRERTHKTILKIIKETDLKVAAHLTCADASKEEVDSVIRDYWRAGVKHFVALRGDSQ
QDSQKGFQRSFQANPDGYQNGAELVAGLKAFSDFDITVSAYPEKHPMSPDFAVDIEMLKR
KVDNGATRAITQFFFDNDVYEAYIERVRRAGIFIPIIPGILPFNNFSKLENIARRCGASV
PDWLAERFEGLENDSTTSNLVGCAVASEQVMDLVNRGVSDFHFYTMNQADLVYAICRQLG
MRAVEEREAKAA
>A0A431NQI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomicrobiales bacterium|TrEMBL
MSESGQVRRSRLLGDGDISVSFEFFPPKTEKMEAVLWASIERLAPLSPRFVSVTYGAGGT
TRERTHSTVSRIVRETRLAPAAHLTCVGASRAEVDEVVRGYWNAGVRHIVALRGDPPAGA
GTRYTPHPDGYATTMELIAGIRRIGAFDISVGGYPEMHPESASLAADIEHLKAKVDAGAT
RIITQFFFDNAHYLRFVERCRAAGIWCPILPGIQPIHNFRQIANFAGKVGATFPAWFARR
FDGLDDDPMTTQLVGAAVCAEQVMGLVDEGVRQFHLYTQNRADLSFAICHLLGLRPSAQS
PAPAAKEAALS
>A0A0R2TSX8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodobacter sp. BACL10 MAG-120910-bin24|TrEMBL
MSIIPRVSFEFFPPKDIEASFRLWDTVQMLAPFQPGFVSVTYGAGGSTRALTHQAVTAIG
RKAGLNVAAHLTCVAAPREETLDIARAYHAAGVRDIVALRGDPPKGKSGFSPSNGGFASS
VELIKALAQTGDFNLRVAAYPEVHPDSQGAARDLDWLKAKIDAGATSAITQFFFKADTFL
RFRDRVLAAGIDFPIIPGILPVENWAGVKAFAKRAGSLIPPVLDAAFSVAARDGREELLS
LTHCTQLCDQLLSEGVEDLHFYTLNRPQLTRDTCLALGLKAKSTLQMVA
>A0A1H7K3N9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ectothiorhodospira marina|TrEMBL
MKTQKQHERTFSFEFFPPKNDEGAKKLKDTWTDLAQLEPRFFSVTYGAGGSTQARTLETV
LDIHKNSGVDAAPHLSCIDSTAEQMRGILQLYKDNGLRHIVALRGDLPSGMRDPGEFRYA
NELVEFIRKETGDHFTLEVAAYPEFHPQAPNALKDMQNFKRKVDAGADSAITQYFYSAEA
YFRFVEDCEKLDINIPIVPGIMPITNYKQLARFSDACGAEIPRWIRKRLEAFGEDSAAIK
AFGEEVITDMCAQLLEAGAPGLHFYTMNQSGPIKAIWKNLGLKPEPK
>A0A6J4YDW4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis Delta 1 endosymbiont|TrEMBL
MFNYPYLIELLSPKKSKDDPTKALLDRFADRYQRIIDAGCGVSIPDNPMGQPRLGALEIF
DLRDLSIDPEKAVMNLNTFHTKSELDGLLQRAAEADLKYILVVRGDGGPLLSKLDAKSIG
GNKSVATSIDLIRYINTEYSDQFIIGAAFNPYNPMPFELNRMAQKVDAGAKFAVTQPIIG
RDESVEMLKGLNIAVIVEAWMSDNIDLLYRSVGKEKDEKAENYDPIANLKTLHDVYPQCS
VYLSMLSFKQNWQDILPRL
>A0A836XL28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MTDTPHLSFEFFPAKTQQGAENLNVTASELNKFNPELFSVTYGAGGSTRDTTKDLVLNLQ
NQGYQTAPHLSIGGGSKSDVLVLIDSYQKAGITNLVALRGDLPSGVGATKKLVHANELVS
LIREHSGDHFNINVGAYPEIHPESESYSNDIYWLGEKFRAGADRAITQYFYNPDAYFTFI
ESCAKTGIDKPIIPGIMPLTNYENLLRFSDNCGADIPRWLRWQLKERSHNSADLISYGIE
MVSELCEKLLAGGAPGFHFYTMNKWQISEQICRNLGFSAKD
>A0A7T0RMU2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alteromonas sp. B31-7|TrEMBL
MVSYAQGVDALNQSLSELRDIDVSFEFFPPKSEKMEQTLWKSVERLAPLKPSYMSVTYGA
NSGERDRTHDVVKRIQQQTGVAAVPHLTCVDASRDELKQIAKDYWDSGIRRIVALRGDLP
PGVQKTEMYASDLVALLKDVADFDISVAAYPEKHPEAPNAQFDLLNLKRKAEAGASEAIT
QFFFDTSVFLRFRDRAAAAGIDLDLVPGILPVTNYQTLVKFAGFTNVHVPGFLHKMFDGL
DDDDQATRNLIGANIAMDQVKVLAKEGVKHFHFYTLNRSELSYAICHMLGVRGNGTK
>A0A836UP85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MIFDDEPLAGENLPILPGHFSPGRFERVLRAGHFAVTAEIAPPDSADPHDVYERAALFDG
YVDAINATDGSGANCHMSSVGMCALLTRRGYSMIMQISCRDRNRIAIQGDVLGASAMGVS
NILCLTGDGVQSGDHPQAKPVFDMDCMTSLQMLGGMRDKGEFLSGRKISSRPQVFIGAAA
NPFVPPLDYRPLRLAKKVAAGAQFVQTQYCFDIDRLKTYMSEIRDMGLDKKVFILAGVGP
LASAKSAEWIRNNVAGVHIPDDIIKRIAGAKDQCQEGVNICIDMVNQVKEIDGVSGAHIM
AYRQEERIAEIVEKTKVLGDRTPWHPNR
>A0A7M2SVX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces ferrugineus|TrEMBL
MAGTGLRALLENVRYEVLPAKATEDKVLAHVPRDVVVTVTASPVKGLEPTLDLTARLAAH
GYRVVPHVPARLLRDDLHLKEVSDRLLEAGVNDVFVPAGDADPPAGVYDGALPVLRRLTE
LGGPFARVGVTGYPESHPLIHDDITIQAMWDKREHATYIVSNLCFDPRVLGEWIARVRRR
DVTLPVYVGVAGPVQRAKLLAMATKIGVGESTRFLTKHASWFVRFAAPGGYAPERLLTRT
QEALTAPSAGVAGLHLFTFNQIAETERWRRALLDRMGG
>D0C724|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter baumannii (strain ATCC 19606 / DSM 30007 / JCM 6841 / CCUG 19606 / CIP 70.34 / NBRC 109757 / NCIMB 12457 / NCTC 12156 / 81)|TrEMBL
MISTLPMSHVSPCFQQNQFFVLVEYLTSLHEIYPVRHEFAGYPAAMTLADRVHSDHDIAP
LEASKSYPDSIDKVLHFSGKARDIQDFEQFLEQAQAANIQNLLLLTGDKLKEHHNGRDGQ
PRSRYLESVNAVMAAKQHGGFRIGVAFNPFKYVEAERDAQYLKLHKKIKAGADFIITQLG
YDIEALKQTKSFLTKHDYSQQILACVMPLTLGRANFMVKHKVAGIVITPHMLKVLAGEKQ
AGHTDRVYLRCALQILICKHLGFAGIHLSACHKPEEQMLLESYIEQYRHLNLKALEELWS
SLWQVKTGKEFTPEIARFSRQPTSKQIIKYRQLHVMHEALFGSKIAKGVGRFIFKASFWE
NSVVAKALLKTEVLSKHSLVGCESCGQCRLGDTLYICPETCPKGLANGPCGGTNLDRCEF
GDRECIHSVKARLAKAVKQTEILKEKLIPTVPLETRGTSSWKNWYLATEA
>A0A6J4XNS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Olavius algarvensis Delta 1 endosymbiont|TrEMBL
MKLKEALQKKKFVVTSEVQAPVDQEPEDLVRSLSQVRGRVDGVSLSEVEFEGIVGDTIKT
CELLNTNQLEPIYQTTTRDKNRLQLQKDLVEAHRAGIDNLLVFTEDYRITGDSLQEMMFF
HVDAGKLQSVLEHIRQGETVEGDSLDAKADFLVGSGVESAWGKNVPDLEMKEMEEMTKMG
AGYFLTTPIFDVDQFAKFLKKAETFDVPVIAEVMILRTAGMARFLNRHIKSGMVPDWIIQ
KLTRAPNRQKASIEIFNDIVSGLKDLCQGVHIITIGAEDNLKLYLDAAKLK
>A0A3L8D9D4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ooceraea biroi|TrEMBL
MRNLIVDEDTCRRSDVARRDSAGGSSSDNVRTARRRCEIVDLRRALQGKISSNEIFCGLE
IVSASRPSGFYQRLLEEMGKYSPLFYALTWHEEAPADTENYLPLNLLENFPSNTLLHLAA
KSFKRDEVIRISRKALALGTINIFALRGDSLSEDGDFKHAADLVAFIREQFGGTFCICVA
GYPQMHPESPSRELDLLYLKAKVDAGADFIITQICFESQAIIDFVNDCRKIGIRVPIVLG
IFVPMSYECLERMASICKLDVPVKIKDDLSRVRDNDEAVTKFAVDLAMQIMTDVIRSGVT
RGFHLFTLNRLPLVAEIYRRIEFLKTEFGN
>A0A3E3K2K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sellimonas intestinalis|TrEMBL
MKIKEKLQSGNVHISFEVFPPKTDDKYESVVKAVDEIATVRPSFISVTYGAGGGTSKNTV
GIASHIQNELHVPSLAHLTCVSSTKAEVREVVHKLKQEGIENVLALRGDIPEGMAYPAED
KFQHAAGLIELLKESGDFCIGGACYPEGHVESDTQKEDIRYLKEKVDCGLDFLTTQMFFD
NHILYNFLYKIREAGITVPVLPGIMPVTNKSQIRRICSLSGTYLPERFKAVVDRFGDNPK
AMRQAGVAYATDQVIDLIANGINNIHIYSMNKPEVAKAIMENLSEIVDE
>A0A2D8WTX9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Porticoccaceae bacterium|TrEMBL
MSDVLAKKHAIQAFMQETSVEVTPAGARAVKDFSXILKPKMTVYVTFLPGSDFRDTLETV
CRLKNEGYCPIPHFAARSIESEKIFEESLAKLRQEANVNEALLIGGGVDIPVGPFTASIE
XLRTGLFDKYGFNRIGVAGHPEGSPDITPKECEQAIREKNEFNQHTDADLYLATQFLFEA
KPLFQWEKTIRDQGNKLPIHVGIPGLATIQTLVRHAKQCGVGPSVRFLKKNPVDMLKMSL
RNTPFSSLVKAPSXNPSKLIFDIVTGIASDXDCLXEKCHLXPLGGLQKSVDWLYQIQDGN
FSVSWDDFNVH
>A0A1C6LP29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vogesella sp. LIG4|TrEMBL
MTERKQTFSFEFFPPRSAEGMSKLRTTRQQLAQFKPEFFSVTFGAGGTTREGTLATVLEI
RNEGHAAAPHLSCIGSTRDNIRAILNEYRNHGIRHIVALRGDMPSGMVEAGEFRYANELV
SFIREEHGDHFHIEVAAYPEFHPQARSAEDDMNNFVRKVQAGANSAMTQYFFNADSYFRF
VDEVQARGVDVPIVPGIMPIANFGQLCRFSDMCGAEVPRWLRLRMQAYMDDTASIRALGL
DVVTELCDRLLAGGAPGLHFYTLNQAGIVSTVWQRLGL
>A0A4X2MAE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vombatus ursinus|TrEMBL
MAAAAVRDWKLPESCRNPAMANEARSSSSLEGSSSGSEGSKDSSRCSTPVLDAERHERLR
EKMHRRMESGDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGADKV
TSSMIIANTAVDYCGLETVLHMTCCHQTQDEITSHLHKAKRLGLKNILALRGDPMGDEWE
DEENGFCHAVDLVKHIRSEFGDYFDICVAGYPKGHPEAASFEEDLQHLKEKVSAGADFII
TQLFFQVDTFLNFVKACTAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEP
IKDNDAAIRNYGIELAVAMCQELLASGVVPGLHFYTLNREVATVEVLKRLGMWNEDPRRP
LPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQAWDEFPNGRWGNSSSPAFGELKDYYLF
CLTSKCPREELLKMWGEELTSEESVFKVFAYYLSGEPNQSGHRVTCLPWNDEPLAAETSL
MKEELQKVNQRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSETVAALL
QVLKKYELRVNYHIVNVKGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDE
AFALWIEQWGKLYEEESPSRMIIQYIHDNYHLVNLVDNEFPLDNCLWQVLEDTFELLSKP
APQ
>A0A3N6DBZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ADI91-18|TrEMBL
MSGLRELLASGQRSFSFEFFPPKTDAGERVLWNAIRRIEAMAPSFVSVTYGAGGSSRDRT
VEVTKRMVAETTLLPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGNPNATWT
AHPQGLRHADELVSLVRASGDFSVGVAAFPEMHPRSPDWDTDIRHFVAKCRAGADYAITQ
MFFHVEDYLRLRDRVAAAGCDTPIIPEIMPATDARQIGRFAELSGAAFPEELAGRLEAAK
DNPADGHRIGVEYATAMADRLLAEGAPGLHYITLNRSTATLEIHQNIIESRSAHALAHG
>A0A271K6I3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium wenxiniae|TrEMBL
MIGRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDCMSLLETCRIMRDNGKFLSGRKLTTPPQLFL
GAAINPFAPPIDFRPYRLGKKIAAGAQFVQSQYCFDVPMFRTYMQQVRDLGFTEKCFILC
GVGPLASAKTAKWIRSNVPGIHIPDSIVKRLEGAQDQKKEGKQLCIDIINEVKEIPGVSG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>J7GSQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Carsonella ruddii CE isolate Thao2000|TrEMBL
MKQISFELFPTFNCINNLINKINIIKPYFISITCGKIDNYLFIKKNINFFKVNIVPHLIC
NEINNVLIKIILFIKLNIYNFLIITGDNYKSNSFYFVKKIRILFGHIIKIFSSIYSENHK
LSINLNKEILFIYKKNKIGINCYFSQFFFNYNIINYFLKIINKTGINKNIIIGIFPKKKI
SEILIFSNYCKVEISNWILKNYFFFNLKNYLLKNIKNKNFHFYTFNNIKNLNYYFK
>A0A2U3AY10|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacteriaceae bacterium LYZ1037|TrEMBL
MKVIEHIKRANGNTQFSFEILPPLKGQHIQSIFDNIDPLMEFKPPFIDVTYHREEYVYKE
LDNGLLQKKVVKKRPGTVGICAAIQNKYHVDAIPHILCGGFTKEDTENFLIDLDFLGINN
VMALRGDAVKTETYFKAEKEGHNYASELVSQISELNKGVYLDEELLNSSATNFCVGVAAY
PEKHMEAPSLDSDIHFLKKKINNGAEYIVTQMFFDNAKYFEFVEKCRKEGITVPIIPGLK
PIATKKQLNLIPHRFHVDLPEALILEIVKCKDNEQVRQLGIEWCIQQSKELQKAGISVLH
FYSMGKSDNIKAIASQVF
>A0A2K6F9Z9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Propithecus coquereli|TrEMBL
MVNEARGSGCLNPRSEGSSSGSENSKDSSRCSTPGLDPERHEKLREKMRRRMESGDKWFS
LEFFPPRTAQGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCG
LETILHMTCCCQSQEEITGHLHKAKQLGLKNILALRGDPTGDRWKEEEGGFNYAVDLVKH
IRNEFGDYFDICVAGYPKGHPEAESFEADLKHLREKVCAGADFIITQLFFETDTFLRFVK
ACADMGVTCPILPGIFPIQGYHSLRQLVKLSKLEVPQKIKDVIESIKDNDAAIRNYGIEL
AVNLCQELLASGLVPGLHFYTLNREMATTEVLKRLGLWTEDPRRPLPWAVSAHPKRREED
VRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW
GEELTSEESVFEVFVHYLSGEPNQNGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILT
INSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLHVLKKYELRVNYHIV
DVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYDE
ESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDAIELLNRPTQSEREAEAP
>A0A4Q2IY04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas desiccabilis|TrEMBL
MTISVNQLEEARRALDAPLFADMAGDAAVSFEFFPPKSAKMEETLWEAVRTLEPLSPRFV
SVTYGAGGSTRERTHATVARIQRETSLAAAAHLTCVEASRDEIDQVAEEYWAAGVRHIVA
LRGDPPVAGQKFQAHRDGYANAAELVAGLKKLHPFEISVAAYPECHPDSGTKAEDLDNLK
RKLDAGATRAITQFFFTPEAFFRFRDAATAAGISAEIVPGILPVSNVAQTRKFAGMCGAA
IPDWMDRLFEGLDDHPASRQLVAATIAAEMCRRLYAGDVRHFHFYTLNRAELSYAICHLL
GLRPNKAAGAVAA
>A0A2Z4VC17|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ICC1|TrEMBL
MSGPQRSAERGRYRPALLPADGERSYSFEFFPAKDEAGERRLWHAIRRVEAVAPTFVSVT
YGAGGSSRTRTIATTHKIATQTTLRAVAHLTAVGHSVAELRQIMGQYADAGIHDVLALRG
DPPGDPNGPWIPHPEGLTHADELVTLVKEVGRFGVGVAAFPERHPRSADWESDIGHFVAK
CRAGADYAITQMFFRVEDYLRLRDRVAAAGCDIPIIPEIMPATDVRQIRRFAELSNASFP
DALAQRLEAARDDRAEGHRIGVGHATDMAERLLAEGAPGLHYITLNRSTAALEIHQNLGL
ARARLSARAAVA
>A0A7C4J864|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTPSPNGNGYLAGSNLEKVLKNGHFAVTAELGPPQNADREVIRKKAALLKGYCDAVNLTD
NQTAIVRMSSIGAGALLMQAGLEPVIQMTCRDRNRLAMQSDLLGAYALGMRNVLCLSGDH
QTFGNHPNAKNVFDMDSIQLVQMVTALRDQHTFQCGEAIKGQEPRFFVGAAESPFASPID
FRPYRLAKKVKAGANFIQTQLVYDLDAFKVFMAKVRELGIHQQTYILAGVGPLKSPTMAR
YMKDNVPGLRVPDRLIERMEQAGAPWAGKSKDELTKEDKKARSAAWQAEGIKICIEIIQQ
LREIEGVAGVHIMAIEWEEAVKPIVEGAGLLPRPIVTEAPLEARQ
>A0A832MDP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MRFIRDVYASAKANGRPVVSFELFTPKTPEGERTLALKTLPALAGLKPGYCSVTYGAGGS
TRHKTIDLVQSIQVNFGVPGMAHLTCIGATRDQILALLMDARQRGICNLLALRGDPPAGT
TSFTPIPGGFRFAYELVELARKVGGFSVGVAGFPEGHIECREGKHVDWQRLKEKIDRGAD
FVITQLFFDNRFFYEFRDHLVRHLHVNVPIVPGIITILNASQIRKFTALSGASIPQTLID
KLHQLGDNDDAVAEFGIEFATQQCADLLRNGVPGIHFYTLNKARSVSRILANLGMADTES
AANTRNAGPCPDREATLSSAAQNKTPTDRE
>A0A6H0H1A7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus subtilis subsp. subtilis str. SMY|TrEMBL
MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQRIHKAYVEAGANIIQTN
TYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTMGGIRTFNKNAYSLDEIKR
SFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETDLPIMLNVSMHEQGVLQDGTP
LSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFDDVFLSVYPNSSLPSLEEGRLVY
ETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAMAEAVGGLAPITEKEVKTRAKEFIS
VHHERTEPGLDEIAAKKRSIIVELDPPKKLSFDKFLSAAAELKEAGIDALTLADNSLATP
RISNVACGALVKQQLDMRSLVHITCRDRNIIGLQSHLMGLDTLGLNDVLAITGDPSKIGD
FPGATSVYDLTSFDLIRLIKQFNEGLSLSGKPLGKKTNFSVAAAFNPNVRHLDKAVKRLE
KKIDCGADYFVSQPVYSEQQLVDIHNETKHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKL
SDTIREKMAHAGEDKEKQKAEGLAIARSLLDTACELFNGIYLITPFLRSDLTAELTSYIQ
QKDEQRQNIFLH
>A0A6N3CKV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus lutetiensis|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYETYNLTHPEKVLAIHKTYIEAGADVIQT
NTYTAKRHRLDGYGYGEKIKEINQAGVKIARQVAGEDTFVLGTVGALRGLKQCELTLNEI
IKETLEQVRYLLETEEIDGLLFETYYDEEEIIEVLKVVRPLTDLPIITNISIHEAGITEN
GRPLVETFGKLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVSRKFVTP
MVEEAELIKAVKQSETIVDKVERKVTIIAELDPPKTLDIRKFTKGVKALDEAGVAAITLA
DNSLAKTRICNVSIASLLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFHQVLAITG
DPSKIGDFPGATSVYDATSFKLLELIKQLNKGIGYSGASIKKETTFTAAAAFNPNVKNLS
RCGRLIERKIAAGADCFITQPIFNSEIIENLAELTRDYDTPFFVGIMPITSYNNAIFLHN
EVPGIQLSDDFLAKLEAVKDDKEKCQQLALEESKQLIDHALKFFNGIYLITPFMRYDLTV
DLVEYIHQKVEQSHQIIP
>A0A7H8Z4J1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomyces sp. oral taxon 169|TrEMBL
MHDNEPTGPTAAAGSRGEALSSAETGTARRLPTVSLELFPPRPGKAASATWGRIDRLLAT
GPDFVSVTYRPTFVTDPAGGVTGGGRRGSEHEPEAGRYEAAPRVRAVQEQTNPSECVLAH
VLDSSTIPLMAHLTCIGYRKQEAVDIVTRFLRMGVRRFLALRGDPPAGTRAEDVAGELRH
ADDLVRVIREVEADFFGDGRRHVTIAVAAYPATNDHIEAIEVLAAKQAAGADMAITQVFY
DAADYVALTNAASYAGVSIPILPGVIPLTDLRRLTRLEALTGVRVPTGLRSSLGSASGAT
LVERGIGATLDLATALLRAGAPGLHLYTFNRTRPALDVISHLRLGGILAGAAPDREVRDT
VDRGYLQATPGRGPSFLRRGSARAAVSSHHPVQPLITITKENA
>A0A523HWJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MQPSGAASQNLRNMLEDSDRFLTGVEIETSRGLLMAETSRKTAELAKSLSEFERVDFVAL
TDNPGGNPHIRPEILGQDLLFRGRDVVINMSCKDYNRNGIESRLWALGSQGFTNVLALSG
DYPTDGFQGLAQPVFDIDSVGLLELIEQMNEGLPNRVWGSVGREDRLEKTNFYAGCAVSP
FKKLEGELMTQYFKLAMKVRTGAKWAITQIGYDSRKFSELQLYVQSTGIEIPLIGSVFIL
TAPAGRFFNRWGMPGVWVSDELRDIADRQAKSRDRGRAYFSELAAKQIAILKGLGYRGVY
ISGRPQLERIRGILETVDSYGESDWKEFAKEINFAQTNEFYYFEQGDNPGLSSNQVNKDY
LASKSKSKLARAKARMTVPLQYRLGKFVHDRVFTEGTLGFKAGRAIYGQVEKSKKLTGVA
HVLEQATKVPVYHCQDCGDCSLPDIAYLCPESECVKNQRNGPCGGTKAGMCEVLDKECIW
LRAYDRLKPYGEELTMLERPVVFRDASLRNTSAWANTFLLRDHHGKKNPADRSGGA
>A0A7X3XZ93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SB0661_bin_20|TrEMBL
MTPRTLQHTLVQGQFAVTVELNPPKGTDVSELLETAKSLSGRVHGINVPDNAAAVLRASP
VAVARLLYEQGHDPVLQVTCRDRNRLALQSDLLGAHVLGIRNVLCLTGDSPGTGDHKDAK
PVFDLDTVQLMHAVQELNEGRDLAGNALEGRTAFFIGGAAAPGAEPAELLHKKFEAKVNA
GAEFFQTQPVFSAKVIHPFMEAVRPYSRKVLAGVLVLRSVKMAEYVNARVPGIDVPDEIL
QELRNAGDARVSEAGLEIAVRTIRAVRPFCDGVHLMAGRLAHRLPEIIRKAELS
>A0A7K2IFI7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID6137|TrEMBL
MGTDLLDDFSLEMTGKDVPALEEARDSIPQGTRINVTFLAGEDHATRLAAARAVRGLGFV
PVPHISARRLPSSAALEEFLAGLAEDGTADNVFVVGGDPARPEGPYEDALAVLRTGLLER
YGVRHIGISGYPEGHPAISGPALWSALTDKAAVIGAGPFTGDVITQFGFDADPVLDWLAA
VRARGVDLPVRIGVPGPAGIRRLVGYATRFGVTTSASVARKYGFSLTNLLGTAGPDRFLH
ALGERYDPARHGVVKVHFYTFGGLRTTAEWVGGFRERTR
>A0A7K9RE26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sterrhoptilus dennistouni|TrEMBL
MVNEIQQTSSASSSSRSDGGSSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQEAGDR
WFSLEFFPPRTANAAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPSGEEWEEEVDGFNHAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVFAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVSMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGLWREDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTSEESVFEVFTCYITGEPNRNGYKVTCMPWNDDPLATETNLLKDELERVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYEQRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVEDTFELLN
>A0A7C4QCP2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPTFLEQLARGPLLADGAMGTMLHARGAAFGGCFDALNLTQPALVAEIHRAYIDAGAQLI
VTNTFGANRYKLAAHGLQDRVREINAAAVALARRVVDAAFKPILIAGDVGPLGVRLAPYG
RVKAEQAYAAFREQIEALVEAGADLIVAETMTDLHEIAEAVRAAQDCAAAHGRPVPVIAT
MTFTRDDRTLLGDPPARVAAALVATGADVIGVNCSGGPAQIQRIAALMRQAAPEARLAVK
PNAGWPEQVEGRIMYPATPHYFGEYAAAFAELGVSVMGGCCGTTPAHIAAMRAMLDAPRP
AWTASLRSPAGVLEREEEEEAPAGSTQLAQKLAAGRFVVTVEMDPPKGVDTHKLLAGARL
LAEAGADAIDVADTPMARMRMSAWAVAHLIQTDVKLETVLHFPTRGRNLLRVQADLLAAH
ALGLRNLFATMGDPTAIGDYPTANDQYDLVPSGLIKLIKQGFNAGVDHAGTKIGSPTAFF
VGCAVNLCPPDLDKEIKTLRRKIDAGADFALTQPVYDPATVRAFLARYEDQHGPLTLPLV
VGVLPLYSLRHANFLNNEVPGVVIPAAMLKRIEAAGEAAPQAGVQIAGEILDELRSIPAA
RGAYLMPQFNRYDLAAEIIDHVRAW
>A0A536A066|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSALASLLRSGEFVVTAELNPPKSAAAAVVRRRAEALKGVVDAVNVTDSNRANVAMAAIP
AAAIVRSVGLEPIVQMTGRDRNRIALQADVLGATAIGIENFVFMSGDDPKQGNHPDAVYV
KDLDGVGLVKMAVGMRDQGQFLSGDEIKQPPKLLVGGTASPFTKPME
>A0A520V141|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSMHSLEIVPKQLDRLKFLPINKFEDVFVAFIPGDNYLNIINACKSLLESGFNPIPHIPA
RTLASKEQLEDFLFQLSSLGVKDILVIGGSPKKQEGPFSESMDLFQTGLFSKYVFTINIA
GHPEGNPDDSESDLNLIEKSKWLFENKLNFSIVTQWTLDVEKTNRWIHEIKNKLIQDIDQ
DIKIKIGIAGPAKLTTLINYAKICGVSATALIVRNKKFGLTKLVKHNPTEIINGLKNYDQ
LHFFPFGGIKELSGWMEK
>A0A5E7YKP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hoeflea sp. EC-HK425|TrEMBL
MSQADSNPLDPSALLEPLPGHSSLGRLERILRRGEFAVTAELNPPDSANPHDVYERAAIF
DGWVDGINAVDASGANAHMSSVGICALLTRMGYAPIMQISCRDKNRIAIQGDVLGASAMG
VQNILCLTGDGVQAGDQPGAKPVFDLDCMSLLETIRIMRDNSKFLSGRKLTSPPTVFLGA
AINPFAPPHDFRPHRLAKKIAAGAQFVQSQYCYDVPMFKKYMQQVRDMGLDKECFIMCGV
GPLASARTAKWMRSNVPGVHIPDEIIKRLEGAEDQKKEGKQLCIDIINEVKEIEGVSGIH
VMAYRQEEFVAEIVHESGVLKGRRPWRKEPNPVDEMVAARMEEILEEPRQVPHELAGVAG
DTEPSE
>A0A2E5T0M5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKKISKILSEKQTISFEFFAPKQLDAQEQLLQSIKEINLNKLSFISVTYSVSKNSGPTDL
IVEKISNETLIPIMPHLTCITHSKNEIDEIINQYQKKSINNILALRGDIPETGQFGKKDF
ENALELVRYLRHNTKLDISVAAHPEGHPDAIDEKSDFLYQMQKIQASDFAITQFFFESSY
YFDFMEKLYKQGNKNPVLPGIMPPTNPDALIRMAKINGSHLPKSIIEKLSSLKDKKARED
FAKETTLDLIERLISNGAPGIHLYTMNNVSLSEKILNEINL
>A0A535T9T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
AGITIPIVPGLMPVPSRRSLAFMAAMTGATLQPDLARAIEEAPDDDAVRALGVRHCIEQC
VELLEAGVPGVHFYTFNRARAPMEILASLRGQQLLTA
>A0A2E2A039|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MYSFLLSSYYNYKNNLNDLISFWSHDMGFIQEIEEIEKKFGNVFITDISPPKGINNLGYE
SIININSDFLLIIDSPGGSVRSAPIPFAYKLSYEENQNVIFTLNCRDMNKLAIQSNLLGA
QXLNLHNVFIVNGDDFTKQKQSVKTVNDYTTTSLISDIVDLNSGIDFQQGKLESITTFTV
GSAIDFSKVPQINEIKLVRKKITXGTDFFISQPCYDTSLILDFHKAYYSQYGXTFEKPIF
YGVQMLSKNGKNWGFIPXDVENEMKSNVSSXEIALKFVQELLSLGFNNXYLVPPIENGGV
RDYXMAQXLXKKIRSM
>A0A2D9SUS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIIDILAKTRPVSFEFFPPRSADGIAAVLETLDELKPYCPDFVSVTYGAGGSTRAFTEE
ITIQAKRTANVEVMAHLTCVGQTVEEINSVLDRLESEGVENIIALRGDPPRGETEFVPTK
GGFQHATDLLKHVTSNFHFGVAAACYPEGHTESVDLKSDLDYVKMKVDXGADFLVTQLFY
DNRHYFDFXERAHSAGISVPIIPGVLPVLNSAQVRRFTGLSGSEIPPDLDKLLDKYAXSD
NSARDMGVEYATAQVRELWDAGVPGVHFYVLNRSYSVSRILDNLVIPGHLRED
>A0A535T6G0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MIAGPPVKPSRLRLDSASREALTRFLSHPRYEVLPTEESGDLVMGNLPTEVTITVTSSPR
RGIEATLALAERLAAGGYAVVPHLAARLVRDEPHLNEILARLDAIGGRVFVVAGDSQEAA
GAFPDSVSLLEAIASHAPAMKEIGVTGYPERHGFIDDDLTIQAMWDKRRQATYIVSNLCF
DVRVVKRWIARVRKRGVPLPIFIGMAGVADPAKLLRVSTRIGIADSARFLRGHTNWLMRL
IQPGGYAPDRFATGLMPELARPDMKVAGIHVFTFNEIEPTEQWRQQMLARLS
>A0A536F4C2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRKTSHSRKERSFSLSALASLLGSKEFVVTAELNPPKSASASVVRRRAEALRGSVDAVNV
TDSNRGTPAMAAIPAASIVRSVGLEPIVQMTGRDRNRIALQADVLGAAALGIENFVFMSG
DDPKQGSHPDAVNVKDLDGVGLLKMAAGLRDGHFLSGDEIKQPPRMTIGATASPFTKPME
ADLTKTFEKIAAGAEFLQTQPVFDLATFSQWLVEVRRADVRAIPIIAGVLVLRSPEQAER
MAKVPGLAIGQQTLDRMKAAADAESEGIAIAVEQARALRALPGVHGVHLYAIEWPEAVGR
VVEAAALLPRPQAKVVAV
>A0A2D6F3Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKIKDILEKTRPVSFEFFPPRQADGIPAVLETLDELKVYSPDFVSVTYGAGGSTRAFTEE
ITFEAKRTAGVEVMAHLTCVGQTKEEIHGVLERLEAEGVENIIALRGDPPRGSTEFVPVE
GGFQHATDLLEHVKSNFKFGVAAACYPEGHTESVDLGSDLKYVKMKVENGADFLVTQLFY
DNRHYYDFVERARAGGIDVPIIPGVLPVLNSAQVRRFTALSGSEIPPELDKLLDKYADND
DSARDMGVEYATAQVRDLWDVGVPGVHFYVLNRSYSVSRILDNLTIPGHHRQD
>F0Z5M3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. D5|TrEMBL
MKIKDRLNENGIHISFEVFPPKTDAGYEKVQEATDRIAALKPNFISVTYGAGGGTSKNTA
KIAEHIKEELEIESLAHLTCASSTKDEVRCVIENLKELGIENILALRGDIPTGMQFPSED
RFHYAWELVEEIRRHGDFCIGAACYPEGHVENEHKADDIRYLKEKVDSGVDFLTTQMFFE
NDIHYNFLYRIREAGITVPVLPGIMPITSAKQMKRSCELSGTVFPRRFQAILDRFGDCPG
AMEQAGIAYATDQIIDLLANGVRNIHIYSMNKPEVAEAIMSNLSEIIKC
>H5YE60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bradyrhizobium sp. WSM471|TrEMBL
MTDVTTTAHTDGQDGHLKRPAISFEFFPPKTEDMERNLWDTINRLAPLDPKFVSVTYGAG
GSTRERTHSTISRILKETALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVALRGDPAG
GIGTAYSSHPDGYQSSADLVAGIKKRHGDIEVSVSAYPEKHPDARDFDDDIDTLQAKVDA
GATRAITQVFFDNDLYFRYLDRVRARGINIPIVPGIMPMHNFKQARNFVTRNGTSVPDWF
AAKFEGLDEDAETRKLVAATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAK
SAQKAA
>A0A2E5J1Y9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKYLYQIVVDTPRARQYNRHTFCGKIVIGXKLSRFSDLLERGEFVITTDITSSTGVDTSG
ISSQLASVEHLVDAVXLGFRNDYNHATPNPIGLIPTILGHGLDAILNVECRDRNRLALQS
DLFAASILGIENIMCVTGDMFIGNEYGDIETVFDVGSXDLIHIASNLSNGIDVIGSHIDN
PPKFYVGGMVNPFASELADEIIRMKDKVEAGAKVFITQPFFDIDRLEEFRAAIGSIQAKV
IASIXVLDSVDXAKRMNNMPGIEIPQNIIMEIESSAEHXSKGIDIAARTINKAKAXYDGV
HIINLGLIDVVRLVLEKSGIKRSSLQ
>A0A536J1A0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MLRAPRYEVLPTDNAAELVAAYVPREVTITVTASPRRGMPRTIHLAVALAKLGYHAVPHL
SARLIHDRVELGQILVALKDAGIKNVFVVAGDAREPAGLFPDALSLLAALPPDHGLTEIG
VTGYPESHPFIHDDMTIQAMWDKRRLATYIVSNMSFDPDGVKRWVGRVRNRGVELPIYIG
MAGVADPARLMRLSTKIGLADSARFLRGHPSWVARMFRPGGYEPGRFVNALLPDVAMPER
RIAGLHVFTFNEIEPTERWRREMLAEIR
>A0A0E1TSS6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderia pseudomallei 576|TrEMBL
MNPIELSFEFFPPKTAEGVDKLRATRAQLAPLKPKFVSVTFGAGGSTQQGTLDTVLDMQK
AGLEAAPHLSCIGSSKDSLRAILDQYRSHGIRHIVALRGDLPSGMGEVGELRYASELVSF
IRAEHGDWFRIEVAAYPEYHPQARSPKADLENFARKVKAGANAAITQYFYNADAYFRFVD
DAAKLGVDVPVVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDKDSIRAFGADV
VTGLCRRLIDAGVPGLHFYTLNGAAATKTVCERLGL
>A0A3M1LZ34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MMEDRSNGYKSGSNLERLIRAGHFVVTAELGPPKGWQREVIERKAKLLHGVVDAVNITDN
QTAIVRMSSIAAGRILVELGLEPIIQMTCRDRNRLGIQSDLLGAAALGIRNVLCLTGDHQ
SFGNHPTAKNVHDLDSIQLVQMVARMRDEGVFQCGEAIKGGGPPFFIGAAANPFGDPFEF
RPYRLAKKVAAGADFIQTQLVFDLPRFKEYMKRVVDMGLHEKVAILAGVGPLKSTGMARY
MRDRVPGMRVADEYVERMKAAVAGIPKEDKAARREAWRAEGIKICVEQIQQLREIEGVAG
IHIMAIEWEEAVPVIVKEAGLYPRPTVSIEPPVQQPCSPQ
>A0A2E5SW09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTSQESISNLQRIISNQQFAVTMELTLPDSPDPXQVINTALXIAPYADALNLTDSTSAVP
HFSSLAAATLLIQNKIEPVMQISCRDRNRIAIQGDILGSQAIGVRNILCVTGDGVQSGDH
PEAKPVFDFDSTSLISTINHMKNTNTFLSGREFSPSLKLFTGGAVNPFAPPXDFRPLRVL
KKXQAGASFFQSQFCFDIERLKTFMGQVEDLSXGNVPPILVGVGPIRSARVAKWMSANVP
GVYIPSKVIDRIDSYPRKEQSKVGKEICIEIVNELKEMRNIAGIHIMAYRWESAAIEIVQ
QSSLDKQARQVD
>A0A535GZ04|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MGCARTATAKFFRTRAASGSRPGKGRDGCPSSRITSSICRNRWTGSCRAPPRGSTSSTAV
TRSRPGAGRAVATVSRLASLLRDGRFVVTAELSSSNSADPDATWRRAEVLRGSVDAINCT
DNTGAHVHMSSLAASHLLVEKGLEPVMQLTVRDRNRLALQADLLGAAALGIHNILLMSGD
DVTAGDHPEARRIYDIDSMQLVEVAAAMRDRGTYLSGRKLEQAPAFFIGAVENPFAPPLE
FRPLRLQKKVQ
>A0A536BBY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARITDLLAAGRTFSFEFFPPKDEDEQRLLTRTISDLQPLQPSFVSVTYRGGRISRERTT
RVVIDLLRTTDLTPMPHLTCVAHPRFELGEIIGGFRAAGLENLLALGGDPLPAEESYKEL
AYASELVELGRHLGFESIGVAAHPAGHPKSPDLVSDREHLAFKLRLADFAITQFFFKVEE
YERLREELAALGVTKPILAGIMPITSLVSVQRMAQLSGYAVPDDIVRRIEAGGDDREEIR
RRGIEVATELCRDLLEAGVPGLHFYTLNFSKATREIYTKLGLVTHH
>A0A3D0CU18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
QLASGEFVITVELEPPHGPDLTEILTTAALLKGSGATVLNVADSPLARMRMSAWAVATLI
QNRVGIETVLHFPTRGRNLLRIQGDLLAAHALGLRNLVVVMGDPTAVGDYPNATDSYDIV
PTGMMKLISQGFNQGHDHGGRAIGQPTNFLVGCALNLTPADFGKEADLLRKKIKAGAGFA
LTMPIWDPEAPARFLEAYGGPIEIPIIAGLLPLYTDRHARFLHNEVPGIIIPEAILRRMS
AAYDQQAEGVRIAEEVLLGAMRQGTIQGVYITPPFRRYEIAARVIRGLRKQGAENREPR
>A0A536JIX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MAPRDESEVDVLERTVAALAGHAPDWVSVTYRVRTGEKTLELVTRIKRHYHIEAMAHLTC
ANTADRTRQILNWMEREGVANVLALRGDPPTTGEPFTPADPQLTHASDLIRLVRGSGYRF
GIGAACSTEKHPESPDVEHEFQYLQLKVESGADFLITQLFFDNRFYFDLVARARAAGIKV
PIVPGLMPVPSRRSLALMTTMSGASVPAALQGAIDEASDDDAIRALGVRHCIAQCAELLE
AGVPGLHFYTFNRARAPIAILAALRGQQLIAS
>A0A3N5RL18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
IPEKLMKRMEDAGDGAAEEGVQIALELIEAIKGKQGVNGIHLMAVGWEEIVPRIVTESGL
QSPQVAVF
>A0A497C4S4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSGKDNGYLVGSHLEKMLRAGHFAVTGELGPPQSADPAVIHEKAALLKGYVDAVNITDNQ
TAIVRMSSIGAGTLVLQDGLEPVIQMTCRDRNRLAIQADLLGAYALGLRNLLCLTGDHQI
FGNHPTAKNVYDMDSLQMVQMVTDMRDKAIFQCGDEFKGQTAKFLVGAAAAPFADPTPFR
PLRLAKKVKAGANFIQTQLIYDIEAFAAYMEKVRELGLHEKAYILAGVGPLKSPGMAKYM
KKNVPGILVPDEVIDRMLEAGKEWAGKKAADLSPEEKKARSKAWQTEGIQVCIDLIKEIQ
KIEGVAGIHIMAIEWEKAVKPIVEGAGLYPRPEVN
>K6J4Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira sp. Fiocruz LV3954|TrEMBL
MKKISEIYGSAKGPVYSFEFFPPKTPEGDLKLMETVKELSRLDPDFVTVTYGAGGSTRSK
TAQILSEISKNYSFPTVSHFTCVGANQEQILKTLKEIRSSGIVNLMALRGDPPKGEGQFK
KTEGGFENATELISFIRSEKLDFCVGGGCYPEKHPNAKNLEEDVENLKRKVDAGADFLVS
QLFFVNSIFENFLNLVRAAGIRVPVIPGIMPITSFSQIERFRSMAGCEFPSSLIKDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKS
>A0A2D9LQG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTTLVELVAKKSRRPFIVCDVSPPRGGSTQLLXSXTNVTPDMFFVAANPGGTVRASSLSV
AQWLESNTKIPALFTMTTRDMNKTAMQTTLLGAHVMGLRNLVVAKGDEFPVSGRWTDVSV
KGFTPTAFIRSVKEMNKRTDFTGQALSEPTDFCIGSTLDISRDWGSEISLTGNKVRSGSD
FLIAQPNFEPVLAGKFLEEYQNDQGADLTVPVMWGVQIMSKDSISFTHVPDQVTKELALG
NSGYEIALEMIHKYLEIGIKDFYLVPPIFRGGRRDYESAQAVIEDL
>A0A521U9V0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MKSDSNLERVLSAGLFAVTGELGPPKNANAAAIKEKASILKGHVDAVNITDNQTAVVRMS
SIAAGYLALQEGLEPVIQMTCRDRNRIMMQSDALGAAALGLKNLLCLSGDHQSFGNHPSA
KGVFDLDSVQLLNMMRDMRDEKKFQCGDAIDIEPRFFLGAAENPFGDPFKYRALRLGKKV
NAGADFIQTQLIYNVEKFARWMEDVRARGLHERVKILAGVGPIKSVGAARYMKTKVPGMD
VPDEIVARMAGAPKGQAKKVGIEIVVDIIKAIKEIPGVAGVHIMAIEWEEAVPEICEAAG
LAPRPVTEAVAVG
>A0A535WP60|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MRIADMLARSKPSVSFEFMAPRDESEVDVMERTVATLAGHAPDWVSVTYRVRTGEKTLEL
VTRIKRHYHIEAMAHLTCANTADRTR
>A0A535DSZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MTRGYCGRLPAVRIADLLNRGRPTVSFEFMAPRDADEVGILERTVAALAGHAPDWVSVTY
RVRTGEKTLELVTRIKRHYHIESMAHLTCANTRDETRRILNWMEREGVANVLALRGDPPG
PGEPFQPVDPELAHGSDLVAFVRRNGYRLGIGAACSTEKHPESPDLEHEFRYLQLKVEAG
ADFLITQLFFDNRFYFDLIARARAAGIKVPIVPGLMPIPSRRSLAFVTQMSGASVPDPLQ
LAIDEAPDDDAIRKLGVEHCIRQCTELLEAGVPGLHFYTFNRARAATEILGALRGQQLLA
S
>A0A2E4JPZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNMISQLXKTLDSXSFAVTAELTXPDSSEKDELVETAXXLSPYCDALNVTDATSAIPHFS
SLAAAYILLDNEIEPVMQISARDRNRIAIQGDVLGAHSLGVRNIFCITGDGVAAGDHPDA
KPVFDLDSISMLAALNNMDKTGSFMSGRKITPKPRLFLGAAVNPFAPPHSYRPHRTIKKW
KAGASFFQTQFCFDIGAMKRFSEKLVELSDGNPPPVLVGLGPLKSSKMAKWLRDNIAGVS
IPDRIIERMDHYPEKEQAQIGLEISKEAIDDLKSIQGVAGIHIMAYRWEEAVKELVEDSG
LSKINRL
>A0A094PJF6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|actinobacterium acAcidi|TrEMBL
MARIAELLAAGRTFSFEFSPPKSAAASMSLGRTIAELEPLGPSFVSVTYGAGGSTREHTR
DTVLWVQRETNVPPMAHLTCVGHTRAEIEEIIATYVEAGIENVLALAGDAPKDPADARPS
DYTYATDLIEHLREISDLSIGVAAHPEGHPRSPDL
>A0A536C6C9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MPAPSRLAGLLRAGRFVVTAELTSTNSADPEATWRLAEVLRGSVDAVNCTDNTGAHVHMS
SLAAAHLLVEKGIEPIMQLTVRDRNRLALQADLLGAAALGVRNIVLMSGDDVTAGDHPEA
RRIYDIDSMQLIEVAAGMRDRGVYLSGRKLEQAPSFFIGAVENPFAPPLEFRPLRLQKKV
RAGADFIQTQLVFDAPLFTRFMSIVGDLGLLDKVFIIPSIGIPRSARSARYMREKVPGLH
VPDAVVDRLEKTPPARQSQEGIQIAVELVKAVREIPGVAGVHLIGIKWEEGVVQVAEAAG
LLPRPTVSPLATVGGSR
>A0A661WCV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MSKLRQALESGKFVITGEVGPPKGVDLGACLHHARELRDKVVAINVTDLQSAVMRIGSMV
VCAKLVEQGLEPVYQLTCRDRNRLALQSDLLSAWAFGIKNVLCLTGDHPALGDHSDARPV
YDLDSVQLLKAASTLNNGHDMAGHELEGKPDFFLGAVVTPAADPLEPQIIKMKKKIEAGA
RFFQTQAIYEPERFEKFMNQVQKLGVPVLAGMVLIKSPAMARFMNANVAGINVPDSIISE
MEETRKEDRKKKSVEITARIIRQVKSLCQGVHIMPLGWDELVPDVIAEAELK
>A0A536P385|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MVATGWRPKAGNRMPSPSRLAGLLRDGRFVVTAELSAANSADPEATWRRAEVLRGSVDAI
NCTDNTGAHVHISSLAAAHLLVEKGLEPIMQLTVRDRNRLALQADLLGAAALGVRNIVLM
SGDDVTAGDHPEARRIYDIDSMQLVEVAAGLRDRGTYLSGRKLEQAPSFFIGAVENPFAP
PLEFRPLRLQKKVRAGADFIQTQLVFDVPIFARFMAMVGELGLLDKVFIIPSIGIPRSAR
GARYMKEKVPGLHVPDSLVDRLEKTAAARQADEGVRIAVELVSAVREIPGVAGVHLIGIK
WEEGVVQVAEAAGLLPRPTFSPRASVGGHG
>A0A2E5BX52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MNIVESNFKNKLTNNEFVITMEVSPPDEFDLQSFFPKFDFLSKTTIDALNITXTARAQGR
MSPLAISSLXQNQFDIETIMHIAVRHRNLLSLHSDXMGAHALGIKNIFSVMGDKPKKDSP
FFNSTFSDLTPNSALKLMNNFNKGISISGEKLKSSANFYKGAAFNPSTQNXEKEIQNLKL
KVESGADFLLTQPFYSTKTXQNILNIIGEFPIPLIIGVLPLRSIKNAQFLQNHVPGININ
SEIMSLMESSKSPIXTGMEISSNIVNXLKGXIAGMYYIPPFNNYKSILEFTKRLELPFSF
Q
>A0A503J990|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. B2-4-17|TrEMBL
MNQFRFSRRPDIGHKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTIDRILKETSLTPAAHMTCVDAARHQVDGVIQEFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALRDAGDFDISVSAYPEKHPESPDFATDIDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A0S9F0B5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidovorax sp. Leaf76|TrEMBL
MNAASAQGTGFPVSFEFFPPKTPEGAEKLRAARQQLYALHPDFCSVTYGAGGSTQEGTFG
TVREILAEGVSAASHFSCIGATRQSVREELAQLKAMGVKRLVALRGDLPSGYGAGGEFQY
ASDLVAFIRAETGRDFQIEVAAYPEVHPQARSPESDLKAYVAKVRAGADSAITQYFYNSD
AYFRFVEETKRLGAEVPVVPGIMPIGSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASI
KAFGLDVVTDLCDRLRSAGVPALHFYTMNQSAATLEICRRLGI
>A0A536PLK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chloroflexi bacterium|TrEMBL
MARITDLLAAGRTFSFEFFPPKDAEEQQLLTRTIADLQPLRPSFVSVTYRGGRVSRERTT
RVVVDLLRTTELTPMPHLTCVAHPRSELGDIISVFRAAGLENLLALGGDPLPAEEQYKEL
EYASQLVDLGRSLGFRSIGVAAHPAGHPRSPDLTSDRRHLAFKMSLADFAITQFFFKVEE
YERLREDVAALGVAKPILAGIMPITSLTSVQRMAQLSGYAVPDDVVRRIEAGGDDRAEIR
RRGIEVATELCRDLLDAGVPGLHFYTLNFSKATREIYANLGLVKSDGRPDVPEG
>A0A6N9HLU9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Massilia guangdongensis|TrEMBL
MANHNFSIEFFPPKTAEGAEKLRVTRAKLSELHPKYFSVTFGAGGSTQQGTLDTVLEIMA
AGEEAAPHLSCVGGTRESIRAILQQYKSHGIKRLVALRGDLPSGYGMSGEFRYANELVEF
VRAETGDWFHIEVAAYPEVHPQARSSQDDMNAFVRKVKAGADAAITQYFYNADAYFHFVD
AAQKAGVDVPIVAGIMPITNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VSDLCERLLAGGAPGLHFYSMNQAVATTALWQRLV
>A0A7V1I4J2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desulfofervidus auxilii|TrEMBL
MRVKDILNATKISFSFEFFPPKTDTGWKQLFDTISELMLLKPSYVNVTYGAGGSTRDRTY
NLVTQIQRETGLTVVSHLSCI
>A0A7Y9XR23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas flavescens|TrEMBL
MIQKKTNVSFEFFPTKTDAGHEKLLNTARELAGYNPDFFSCTYGAGGSTRDRTLNTVLQL
DGEVKVPTAPHLSCVGDSKAELIELLNLYKSKGINRIVALRGDLPSGMGMSSGELRHAND
LVELIRQQTGDHFHIEVAAYPEMHPQARNFEDDIANFVRKAKAGASSAITQYFFNADCYF
YFVERVRKLGVDIPVIPGIMPITNYSKLARFSDACGAELPRWVRKQLEAYGDDTQSIQRF
GEEMITAMCERLLQGGAPGLHFYTLNQAAPSLAVWKNLQG
>A0A7Z0IBM2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pantoea sp. WMus005|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEETLWTSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCVDATRDELRSIAQDYWNNGIRHIVALRGD
LPPGSGKPEMYGSDLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVSTGIDVEIVPGILPVSNFKQLQRFATLTNVRVPGWMSAMFA
GLDDDPETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVAA
>A0A7Y3LTW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. S3(2020)|TrEMBL
MNPTSTARTAVGTSLLEDYSLEMTGKDVPKLVAARDSIPQGTRINITFLGNEDLPMRLEA
ARAVKRLGFVPVPHISARRLGSRDDFERFLAGLRADGTSDNVFLVGGDPAHPEGPYEDAL
SLIRTGLLREYGVREVGITGYPEGHPEIGAEALWAALEDKHSALAGQPLEAGVITQFGFD
VEPVLAWVEKVRARGIGLPVRIGVPGPAGVRRLMSYAARFGVGTSASVVKKYGFSLTNLM
GTAGPDRFLRDLAAAHDPARHGELKIHFYTFGGLGATSDWAARFRKDTLA
>A0A2V4JF73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. MB-090624|TrEMBL
MSLLKTALREHHFVCVMEFVPKASAERFAAMQAIMDRAQLCGWPMTVAIGDRVGSPLDMS
PLDALASFDRPVPALPHFSGKDRERHHLLAQLQRMEAAGLDQLLLLTGDRLPGHEPGQRP
VRYLESVAALQIARQACPHWLLGAALNPFKYHEEEGGAQYFKAEKKLAAGADFLTLQLGF
DAAKHQEAMHWMRRQAAPKPMLACLMSLTHGRAAMLDHVAGVTVTPSMREMLEAETAQSK
AFAQSRSVDRLALQIIGTKLMGYAGVHLSGIHDLKQLLALEARLAYWQTHVHTLEQWAPA
WQASWQMPGLPAVTFHPPQANWRQGESRVDASFKEKARYHLMHGMHGLLFSRRNSLSKAF
GWAVRQPLWTTRLGAQVLHTLERSVKRPLVGCDTCGRCRLEDTLYTCPETCPKGLANGPC
GGTALNRCEFGDRECIHSIKYRTAKAVGQTAVLRERLIPCIEEQTRHLSSWPQWFAPPTP
RRVSPQPAPRTQPES
>A0A1H1ZLQ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudarthrobacter equi|TrEMBL
MSPTSPVGTQPNPSDTAPVALSYELFPPRSPAAAETLWTTIRELETTAPDYVSVTYGASG
SNRDTALELIDRLLLETTLRPLAHLTCVGNTPEQLAGVIGQLLDTGVRGILALRGDLSND
ASQPVNGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPARHPESPSEEHDVEVLL
AKQRSGADFAITQVFFDSSQYLDLLSRARRAGVTIPIIPGVMPFTSLRRVKRLGELAGVE
PSAELTERLAAADTDIERLRIGVDATVDLANAALDAGAPGIHLYTFNEHQSALEVLDKLA
LPRHTRAGSLSVANRTQLAS
>A0A3E4KP16|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroides intestinalis|TrEMBL
MRIIDLIHSNEKTAFSFEILPPLKGTGIEKLYETIDTLREFDPKYINITTHRSEYVYKDL
GNGLFQRNRLRRRPGTVAVAAAIQNKYNITVVPHLLCSGFTREETEYVLLDLQFLGITDL
LVLRGDKAKHESVFTPEGDGYHHATELQEQINNFNKGIFVDGSEMKVTNTPFSYGVACYP
EKHEEAPNIDTDIYWLKKKMEAGAEYAVTQLFYDNQKYFDFVERARKAGVTIPIIPGIKP
FKKISQISMIPKTFKVDLPEELACEAMKCKTDEEAKQVGIEWCVKQCKELVEHGVPSIHF
YSIGAVDSIKEVAKLVY
>A0A2E8C3A4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonadales bacterium|TrEMBL
MTTNAPISFEFFPTKTEAGHEKLLATAQTLAAAGPEFFSVTYGAGGSTRDGTRRTVLQLD
GEVKVPTAPHLSCVGDSREDLRTLINDYRANGIQRIVALRGDLPSGMGHASGELRYANEL
VEFIRAETGDHFTIEVAAYPESHPQAPNFETDLQNFIRKARAGADSAITQYFFNADCYFH
FVDRVRQAGIDIPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDSISAFG
TEVISQLCERLLDGGAPGLHFYTLNQAEPSLAVVRNLQGDR
>A0A2S5JMA9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Albidovulum inexpectatum|TrEMBL
MTTPRISFEFFPPRDLEASFQLWEAVQMLAPLGPKFVSVTYGAGGTTRQLTHEAVSAIRS
HYGLNVAAHLTCVDATREETLRIARAYAESGVQEIVALRGDAPQGAERFTPHPEGFASSV
ELIEALAETGLFTIRVGAYPESHPDAPDMAANVAWLKRKIEAGASSAITQFFFEAESFFR
FRDACEKAGIDAPIIPGILPIVSWQGARRFAARCGANVPGWLEAAFEKAERDGRVDLLAT
AVITELCDDLLRGGVGDLHFYTLNRPQMTREICHALGIAPQVSLQNVA
>A0A0X7JJD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albus subsp. albus|TrEMBL
MALGTASTRTDRARTVRDLLASGKQSYSFEFAAPKTEKGERTLWNAIRRIEAVSPTFVSV
TYGAGGTSREGTVRATERIATDTTLTPVAHLTAVNHSLAELRNIIGQYADAGIRNMLALR
GDPPGDPMGDWVQHPEGVLYAAELVRLIKESGDFCVGVAAFPEMHPRSTDWDTDVRHFVD
KCRAGADFAITQMFFYAEDYLRLRDRVAAAGCETPIIPEIMPVTNVRQIERFAQLSNAAF
PPELAERILAVKDDPAAVRSIGIEYATQLCARLMAEGSPGLHFITLNHSTATLEIYENLG
LHQQS
>A0A2N1FBV1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tenacibaculum sp. Bg11-29|TrEMBL
MKVTEHIKKAKGKTLFSFEIIPPKKGNNIQDLYSNIDPLMEFNPPFIDVTTSREQHLYID
KGNGLLDRKITRMRPGTVGICAAIKHKYDVDTVPHVLCGGFTKEETEYLLVDCHYLGIEN
VMALRGDAMSHQRYFEASKDGHKYASELVDQIKSLNKGKYLHDVIEANHKADFCIGVAGY
PEKHLESPSLQTDLKRLKEKIDAGADYVVTQMFFNNQKYFEFVDAARKIGITVPIIPGIK
PISVKRHLQLLPQVFKIDLPEALIKSIDGCKNNKEVRQVGVEWCIQQSQELLAAGVPLLH
YYSMGKSDNVKAIAKALF
>A0A524KC51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MSVVLDTLACSRERISIEVVPPARGADPDRVLSCVDAVMPWDPAFVSVTNHPAGRVWVDD
DGTPRSVPIRSKPGTLGLCVAIRSAADVAVVPHAVCIGNDSYRAEDELIDFRYAEFHDVF
VVRGDVRFAPFSEAPRGGFSEALELVRLASAMNRGEYSGGATAGRPAGLSIGVAAYPEKH
PAAANPDSDMAAFRAKVEAGAEWSLTQMLFDARVYSRFVERARGVGLRIPIIPGIKPLCS
LKSLSSVPGTFFVNVPQELASELEDAPTPAEGRLVGLRHAARLCRDLYDAGAPCIHFFTM
GRARDTVDTLAAVFGLVTGKGTPL
>A0A316TIV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides silvaticus|TrEMBL
MRNKDVATVRRLLEHARYEVLPTPTIEDKVLTSVPTSVPVTVTASPSMGLERTISTAERF
AAAGYTVVPHLAARMVSGRTELEELAARLGEAGITTIFVPGGDADPVGDYKDALSMLEDL
TAIGSPFAEVGVTGYPESHPTIHDDLTVQSMWDKRKHATHVVSNLTFDPGVIKDWLHRMR
LRGIELPVLLGVPGPVERTKLLGMATKIGVGDSTRFLSKQKGLMARLVAPGGFSGESFIE
KCAPTVGEAEMRVTGLHLYTFNQVAETEAWRQDWLQRLAR
>A0A524IB93|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spirochaetales bacterium|TrEMBL
MALKDKLEKNEFALLAEFVPPKGTDVTLFLEHAVRLKGKLDAWLVPELPGAVMRMSSLGG
SYLLLQNGLEPVMEINGRDRNRLALQADLLSAATAGIKNIVAAKADSPQAGDMPETKAVN
DLNTSDLLDMLAGFNRGSDFSGRDLPGSTDFTIGATAEHLSGGLTKLTEVGVAFVIAPPV
FDAAGIESALTLCRTANIKIIPTVMVLKSVGMARYIQAHSDSMRIPDPIIERIQAADSVQ
RESIKIAREIISILKKEGCAGVLISSMGWECVIPEILES
>A0A1V5KNF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium ADurb.Bin478|TrEMBL
MAEAEKPRSCSKADALLSRLEQSVLVCDGAMGTLLYQRGIFINRCYDELNLSAPDLVLDI
HRQYAAARADILETNTFGANRLKLKAHGLESEVERINQAGVRLARQAVGPEGLVAGSIGL
LGVPLAPLGIVSEEEARSIFRQQALALLNEGVDLFILETFSDLNELTLALQCLRELSDLA
LVAQMSFDAEGVTKYGLSPEAVVPGLIAAGANVIGANCSVGPQMMLEVVERLAHSGGRFL
SAQPNAGNPRMVDGRLIYLSTPEYHAEFARRFIAAGVQIVGGCCGTTPEHIKAIANAVAA
VRPRRIRPTAARPGKNTLQVETVPREEKSALAARLGKKFVLSVEVLAPRGVDVAPVLNGV
RKLVGFGVDAINIPDGPRASSRMSPSALAQLIERSLPVETILHYCCRDRNLLGMQSDLLG
HYALGLRNILAITGDPPKLGDYPDATAVFDVDSIGLTRMINALNQGYDLAGNAIGRATGW
HIGVGANPGALDLDLEIRRLYQKAEAGAEYVLTQPVFDIAQMERFFQRISDLRLPVLAGV
MPLMNFRTIEFLNNEVPGVTVPEAVVRRMAAAADAGESRAIGIDIAQRSIQALRDRTPIQ
GLYLMPPFSKDKYEIALEVLAVLR
>A0A1C6AFM4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MNLREYLKETNLITDGAFGTYFAAKYQTQEIPELANLSDPEKVKKTHEEYLNAGANFIRT
NTFAANTETLQESFPEVEKNIRAAVEIARSAADGKNVWIAGDIGPIPVNGTEDAAAAADE
YYQIAKTFAETGVKVLDFETFADLDGILPAIKKIRAEYDMFIAVSFSVNQFGYSAAGLSA
KRLLADAAAVPEIDAVGLNCGVGPAHMRQILEKAGRPGDKFLLAIPNAGYPTLTRNKLQF
GNTPVYFAEKMKELQELGADILGGCCGTDPEFIREMSARDGILKKSAPEKEAESSGQSEH
VVRHGFLYDENGNRKEKKLIAVELAPPFDADDEKLLESAHLLKNAGVDVLTFPDSPSGRT
RVDSVLMANKVRQATGLNVMPHICCRDRNAIAMRSLFLGAAINDIYNFLIITGDPIPSTA
RQTVKAVFNSDSTGLMKIAKEMNEDVFAKNPLCYGGAINQGRKNLDVEIGRVKKKMEEGA
EFFLTQPVFTEEDAARLRRIKDETGARILCGIMPLISRKNAMFMKNEIAGVNVTDEIVAR
YPEKASRKEGEAVGIQLAKEVMKLVEDFADGYYFSFPFNRVYMLKDICNCSVGLRTCCAD
RNKTQA
>A0A853NXY4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Arcobacter] porcinus|TrEMBL
MFEILIQKLQEDKFLTLETTPQHEPSMHNIIEKIRKFKIDSKVDGFTCTDNPLAKLKYSS
LFAALKLQTEFKKPVIATMTMRDRNRIALQSDILGANDFDIRAILALTGDPAHMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDVSGRPFKIEPKQIFPFSVVNSYAKNFGSLEKKMHQKI
QNGAVGVITQPIFDIENVKKLLETFENAKENVEGEKRKSQLILGLFPITKLRTALFLSAQ
VPGIHVPQMWIDELEKAHTISEEEEYKVGMQLSQNLFKEINKIHPKIHLMTSNNKFDVAS
EILS
>A0A5C2HAG6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Arcobacter] porcinus|TrEMBL
MFEILIQKLQEDKFLTLETTPQHEPSMHNIIEKIRKFKIDSKVDGFTCTDNPLAKLKYSS
LFAALKLQTEFKKPVIATMTMRDRNRIALQSDILGANDFDIRAILALTGDPAHMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDVSGRPFKIEPKQIFPFSVVNSYAKNFGSLEKKMHQKI
QNGAVGVITQPVFDIENVKKLLETFENAKENVEGEKRKSQLILGLFPITKLRTALFLSAQ
VPGIHVPQMWIDELEKAHTISEEEEYKVGMQLSQNLFKEINKIHPKIHLMTSNNKFDVAS
EILS
>A0A4Q0ZTI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arcobacter sp. CECT 8983|TrEMBL
MLTDKIRNKENGILLYGITPPKVKHTQEEIKEIAKKHVERISKLNVDGLVLYDIQDESDR
TDEKRPFPFIKTINPCEYSKNYLQELKTPRIVYRAVGNYTAKQFATWLESTKATQVHSVF
VGAASHEQQTNITLKEAYNIKKEVNNNLCLGGIAIPERHMKKHDEHLRVFSKQNSSCEYF
ITQCVYDLHAAKTFLTDYAKYAKENNIEPVPIIFTLTPCGSAKTLDFMKWLGINIPNYLE
EDLKESGDILHDSVKLSRDIFEDLFIYGKKRGIPVGCNIESVAIRKAEIDASVELLEEIR
QIIKDNK
>A0A550HZD3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gramella sabulilitoris|TrEMBL
MKITEHLEAAKEKTLFSFEILPPLKGYNINSIYENIDPLMEFDPPFIDVTYHREEYVYSE
KENGLLEKKIVRKRPGTVGICAAIQSKYGVDAVPHILCGGFSKEDTENFLIDLDFLGIKN
VMALRGDAVKSETYFKPEKNGNCFAKDLVYQIYDLNSGKYLDEVIEKGHNTDFCVGVAGY
PEKHMEAPSIDKDIQRLKEKIEAGAEYVVTQMFFENNRYFEFIEKCRESGIDVPIIPGLK
PIATKKQLSVIPHRFHVDMPDCLIREVEKCKDNAAVRQVGIEWCIQQSKELIAGGVPVLH
YYSMGKSTNIQKIATAVF
>A0A0A6PPW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Thiomargarita nelsonii|TrEMBL
MTSQQQALTISCEFFPPRTEKGMLKLRETREQLQDLQPAFFSVTFGAGGGTREKTFETVL
EIQKQSNFEAAPHLSCIGSTHENILKLLQDYQAHGIRRIVALRGDKPSGWAGTFGDISYA
NELVEFIRAETGSYFQIEVAAYPEFHPQASSAKDDLDYFKQKVEAGANSAITQYFYNADA
YFRFIDSCTERGIDIPIVPGIMPITNYEQLTRFSDGCGAEIPRWLRWRLKDLADDKEAVQ
AFGVDVMTSLCERLLAGGAPGLHFYTLNQASFTLEIAKRLGL
>A0A373Q4G1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruminococcus sp. AM54-1NS|TrEMBL
MKTCELFKKKTTLSFEVFPPKSSTPVESIYSTISQLQPLNPDFISVTYGAGGSTNNATID
ICSAIKNHHKIESVAHLPCLYQTKKRVLEQLEEMKSANIENILALRGDRNPDFEPAGDFH
YASDLVSFIKEHSDMNVIGACYPECHPECDSIVDDIKHLKDKVDAGCSQLITQLFFDNST
FYDFREKTAIAGINVPIEAGIMPVTNKKQILRMTTLCHATLPKKFLKIMDKYENDPIAMR
DAGIAYAVSQIVDLIANDVDGIHLYTMNNPYIAEKICEAVKSLF
>A0A2P1UD27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Microcystis sp. MC19|TrEMBL
MTTRLQRAVQDQEFLITAEITPPKGGNTSHMLEMALWLKNRVHAANITDGSRAVVRMSSL
AASAILYQHDIEPICQMACRDRNVIGLQADLMGAHALGLRNILALTGDPVKAGDHPKARA
VFDLESVRLLKLIDKLNKGFDFNDKSLPDGPLELFAGAAVDVQSKSWSGLQSRFERKIEA
GAQFFQSQLVTDFDCLDKFMQQVASLADKPILAGIFLLKSAKNAVFLNKNVPGVQIPDQI
IQRLADAPHPLEEGIKIAAEQIKLAQQLCQGVHIMAIKREDLVPKILDVAGIPPIHN
>A0A1C5KG70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MTRLSEMMKEKQLLSFELFPPKTDKGMNNLPETIKKLCEFHPEYISCTYGAGGGNVGRNR
EVCQEIIKAGTVPVTHFTVIKNTKEGIKEQLQNYLADGVDHMLALRGDIPRGETTTCGDF
NYATDLVAFVRKEFGDKFEIAVAGSPEGHIACRSLEADIAVLKQKQDNGADYIMTQLCWD
MEQFKYWLDAIDKAGVTMPVDVGIMPILDQAATINMALSRNGCVMPRELSRLISKYWIFP
NPFDKEPFDDALEQKKADFKKAGIEYTIRQIDEYRALGINGIHLYALNKWKDVAEIINAS
GMRTMI
>A0A1C6JTE0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MRIEEMFKTGKPVLSFEIFPPKRNRELEEIDDTLKVLCELEPDFISVTFGAGGRGISSRT
VELAKKIRRDYHVEPLVHLTCLNYTKQEICEILNELEAAGLENILALRGDRNPDVEPKQD
FQYASDLVKFIREYGGFHISGACYPEGHTEAKNRIQDIRNLKHKVDEGVTHLVSQLFFDN
EFFYGFQEKARIAGIDVPIEAGIMPVINKAQIERMVSLCGASLPAKFQRIMSKYENRKEA
LFDAGMAYAVSQIVELLANDVDGIHIFTMNNPKVAKRICTEIRNLI
>A0A1C3VUX1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium lusitanum|TrEMBL
MSSKSENGQGGIRISFEFFPPKSEEAEQQLWNTVSELSEWEPEFVSVTYGAGGSTKAPTL
SAVRKMIHETPFTTASHLTCVGATREDTHRVIDEFLATGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVTALRERGDFDISVSAYPEKHPESRDTVADIDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRATGIKIPVVPGIMPIQNLTQLKRFAGACGTSIPSWLDERFDGLDE
NTDERAKVAADVAAEQIQDLMRRGIHEFHLYTMNRSPLVSAVLERLGLQRKVDARAGAAA
>A0A1C5L5W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKITELFKQGEFVVSAEVGPPKGIHIEGLLEEAKTYLSGITAVNVTDNQSSVMRLGSLAT
CKALKDEGLTPIYQLTCRDRNRIALQSDLLSAAMLGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKQLESGVDLGGNELVGEPPKFAKGAVVSPCSDSVDAQLAKMERKVMAGA
DYFQTQAVYEPEKFIKFMEKASQFGKPVQLGIVIPKSAGMAKFMNKNVAGIHVPDEMIEE
LAKDKEKTKAGITGVEIAARIIKKCKPYCQGVHIMALGWESKVPDLLKLAEI
>A0A1C6KZ14|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Clostridium sp|TrEMBL
MKMKELFDRGEFAVSAEVGPPKGIHVDELVEEAKTYLTGVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMNPIFQLACRDRNRIALESDLLSAAMFGIDNILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNQLVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSAGMAKFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A7D5MBW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosotenuis sp. DW1|TrEMBL
MLIRYEINPPRVIQEKVLSHKEVQSSLDKLKKRIFEISKYCSGIHLTDSVLGVPRISPIT
TGALIRNDGLKINITASLRVRDRNLISLTQSVYDAVLLGLDGLLILKGDEPPEGPKDSKL
APSEVVKYFKDLGFGENLDFYLSIPADPNFDKIQKKIDVAPTGFVTQVIQAPEQVFRIVD
RLKPQGFRIIPVIMVPSEKNAKSFAMLGVDQAKFKDRFVDFVTEIHRSTGDVLITSPNDF
RAASEILEQLKELKRN
>A0A160F963|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Anoxybacillus sp. B7M1|TrEMBL
MGFLEELQKRIIIADGAMGTLLYSHGIDRCFEELNLSKPEDIIHIHEAYLDAGAEVIQTN
TYGANYMKLARYGLEDDVKEINRAAVKLAKQAASGRAYVLGTIGGLRTFKKSAITLEEVK
RTFREQLYVLLHEEVDGILLETYYDLEELQTVLAIARKETTLPIIAHVTLHDVGVLQDGT
PLSDALSQLEQLGADVVGLNCHLGPYHMIRSLEAVPLPSTAFLSAYPNASLPDYRDGRLV
YETNAEYFKETALSFREQGVRLIGGCCGTTPKHIAAMAQALIDRTPIQTKQVKQQQATIS
IPSAEPKSEPPLEDIVKKRRSVIVELDPPKKLGIGKFLEGAKALKETNIDALTLADNSLA
TPRISNVALGTLIKQQLGIRPLIHITCRDRNLIGLQSHLMGLHTLGITDVLAVTGDPSKI
GEFPGATSVYDLSSFDLIQLIRQFNEGISYSGQPLGQKTNFSIAAAFNPNVRYLDKAVQR
LEKKIQCGAHYFISQPLYSEQKIEEVYEATKHLEAPIYIGIMPLTSARNADFLHHEVPGI
TLSDDIRSRMAACAHDPIQSAREGIAIAKSLIDAAFDLFRGIYLITPFLRYEMTVELVRY
IQEKERSISERKVLHHG
>A0A240EDC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter puyangensis|TrEMBL
MSTLATYFSKRQFCFSIEYIEHGQTQLDFIQDIAGDPTCVAIADRVHADEDRAPIEITQS
LISNTSVTQQNVLLHYSGKGRDISDLKQFLQEAAQRQYFDVLMLTGDRLKNHDFGQTQPK
QRSRYLESVNSVMYAKQADSRFHLGVAFNPFKYTESEREAQYLKLHKKIKAGADFIVTQL
GYDLLQLKQLQLFLTQHAYHIPVMVCVMPLTYARAKSICKQSVAGIVIPPDLLEFLKQEH
LRDAKDAEDKVYHRAALHILIAKHLGFAGIHLSACEQPQQIRQLEQAILKFQDLDFSQCW
QKYLDLFGLPDMSALRPDLIPPQSIGARQMLKYYSLAYIHDALFNSKVAMVVGRWLFKAK
FWQHPVADRTILAVEHGIKSISVGCDRCGQCRLADTLYICPETCPKGLANGPCGGTSLDR
CEFGDRECIHSQKYRIAKQAKQLSVLKQNLIATVPIQSRQHSSWVKWFNPAQDRHKQSS
>A0A7X9LCL5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus ursoris|TrEMBL
MSKLLDKLKTDILVADGAMGTLLYADGLESCHDYYNISHPERILAIHKAYIDAGADVIET
NTYGAKRHRLKSFGYDNDIKEINQRAVEIARQAAGENVFVLGTIGASRGLKQCELSLEEI
VEETVEQAQALLETKQLDGLLFETYYDREELEAILKAIRPLTDLPLITNMALHEAGITED
GRPLVEALSNLVMLGADIVGLNCHLGPYHMIQSLKQVPLFAQSYLSAYPNASLLSFVSDD
EKGQYRFSQNADYFEYCARLFVEEGVRLIGGCCGTTPDHIRAIKRGIKNLKPVERKVITP
LITEQEFIDEISKKETLADKAKKEVTIIAEIDPPKTLAVDKFVEGIKALDKKNIAAITLA
DNSLAKTRICNLSLASLLKDEVTTPFLLHLSCRDHNMIGLQSRLLGMDVLGFDQILAITG
DPSKIGDFPGATSVYDATSFKLLSLIKQLNQGKGYSGASLKRATHFTAAAAFNPNVRQLE
KSSRLIERKIKAGADYFITQPIFNKETIHQLGELTKAYDQPFFVGIMPITSYNNAVFLHN
EVPGIHLSETLLEKLKAVKDDKAACQAAALAESKALIDCALNYFKGIYLITPFLRYDLTL
DLIDYIQERTAVMKKRA
>A0A7Y3H216|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saprospiraceae bacterium|TrEMBL
MKVLEHIKEGKGKTQFSFETLPPLKGQNIQSIFDTIDPLMEFNPPFINVTYHREEYIYKE
VGNGLLEKKVVKKRPGTVGICAAIQNKYQVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAIKNETYFTAEKNGHKYAEELVKQIEALNRGEYLDDDLQNHAQTDFCIGVAGY
PEKHSEAPNMESDIHFLKKKIKNGASFIVTQMFFNNKKYFEFVDLCRAQGIDVPIIPGLK
PLSTKRQLNVIPQRFGAELPDALIQEAIKCKSKESVRQLGIEWCIDQSKELMKAGVPFLH
YYSIGRSENIRKVALEVF
>A0A6J7D274|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MRIDTLLAERTEPLFSFEFFPPKTEEGEKNLLEAVAALRELDPAFVSVTYGAGGSTRDKT
LEVVDTIKKEYGLEAMAHFTCVAATVDELRATLDKLSDIGVENVLALRGDMPDGGDWTAT
EGGLSYSSELVELINREYPQFAIGAACFPETHVAATSPEDDLAHLAEKVTAGTDLLVTQL
FFDNAVYFDFVDRARAAGITVPIVPGVLPITNIAQLTRITSLCGAALSHDLMAELNARAD
DPEAVHQFGVAYATLQCAELLAGGAPGIHFYTLNRSPATRAILSALRLHRPWENSKS
>A0A6J7P8E4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|freshwater metagenome|TrEMBL
MKSGLTYSFEFFPPKDVEGEERLWAAMSALESIAPDFISVTYGAGGSTRDRTIRITSEIT
ARTHIPTVAHLTCVGSTRQELIEILGKYRSAGIKSILALRGDPTGGPRSPWSATPGGLNH
ADELVTLAAEFGGFTIGVAAFPDGHPASDGDIDKDVQVLLEKEKRGATFATTQFFFDAGK
WKTLVDKLEAQGSTLPIIPGILPVTNVKQLNRMAELSGVPIPSHISERFAKVEDNPEDVR
KLGVEIATKLCEDLLEAGAPGLHFYTMNTSSATREIYSQIKDER
>A0A7S3U2I7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emiliania huxleyi|TrEMBL
QRLYMRLSLEVLPTKLLGSGTSSLTTSLLALVPRGTRVYLPSLPGDAPAAMGAALAHLHA
SAPHVEPVPHIAASRVPSEAELLRRLDSWQEACSNQLSEVLVVRGDEGAHDTAAHGNPAS
PRPSGGPFATTLDLLESGALARRGVETVGLCGHPEGIGATVSTGEGIVHLKGKTAALRRA
GQQPRIVTQICFDAERATGFVDALRAAEEEAPVSLGLVGPAKAQLLQRMALQCGVRPPPP
ATEPSELLERVAVWQRLRGQRHGAEAIHIYPFGGLRTTLQWLLRVEGE
>A0A7S3X5T1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Emiliania huxleyi|TrEMBL
MGDDLRPLWIDLTWGFGDVGARTVAAARHIQKATGLPVLMHLICTDMTVADLDAALDAAL
LAGVRAILVMRGYTQAGYDCWQPCAGGLQHADDLVRHIRRRHGAHFSLGVVGFPEAHPES
RAGAGVATEAERAEDVRRLKRKVDAGADFVICQFTFDAATWGSFLRRCRAEGIRVPILPG
VQPLTEYASARLLASSWRVELPAEVGANLRALQGDAEGARACGAAFVAAVCDATLRQAAG
SGEGLGLHVFVYDGEVETRALLEALAAQGWRRGQLPPDPPPAPSPARPPAAALAIAEGRR
GSTTAVH
>A0A2N2G8Q5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-3|TrEMBL
MKSGSRLERILTSGEFAVTGELGPPKNGNAEHVREKARLLKGSVDAVNITDCQTAIVRMS
SISAGLLTLAEGVEPVIQMTCRDRNRIGMQSDILGAAALGLKNLLCLTGDHQKFGNHPGS
KGVFDMDSIQLLGMVKTMRDEKKFQCGEVIKSHEPKLFLGAAANPFAGPSEQFRAARLAK
KVANGADFVQTQIIYNVERFARFMQAVRDLGLHKKVHILAGVTPPKSVGMARYMKSSVPG
MDVTDEVIMRMQGAKDKEDEGINICVDIIRQVREIEGVAGVHIMAIEWESAVPEIVSRAG
IATRPVFADEPVALAAPVSAIEIRTAAAGGEEGDAVLAAAKVEAEKIIAAAKAEAARYRA
SASSVSGAAGTSGAGAVDQARIEIEEAGEDAMNEKERQMALDSVRLALVKFAGAEAILKR
EPVLAVPASPAPAPVAQAAPAVPVAPAPVQDESAAKKAAEAAAADEAKKAEAAKKGAADK
AAEEAKKAEAAKKAAEAAAADEAKKAEAAKKAAADKAAEAAKKPVAPEAKKAAPAASAAA
VGAAELTLEKTPLNERAAKVPEASYKQAYTGAIRQTLLGDEASGIKVGGANTLPFHLFEG
TMGNNPKIAFDVLDVKPDEWPDSLARHYQDVLDNPVAWAQKCVKEYGADAICISMVSTDP
NGLNRPAGEAAKAAAEVVKSIEVPVIVWGCGNGEKDTETLREITSLIGDKKVCLAPLSDS
NYRAIGATAMAFRYPMVAASPIDVNLAKQLNILLENLGVSLDSVLIDPSIGALGYGIEYT
YSVMERIRLAALTQKDEKLQVPFICNLGREVWKAKECRLPSDEMIGDQETRGILMEAITA
SCMLMAGGELMIMRHPRAVSLTKSLINGLMG
>A0A7V7XNQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MKPEISFEFFPPQTAEGAEKLRATRRQLAQLAPAFFSCTFGAGGSTRDRTLETVLEIQAE
GLPAAPHLSCIGSTRDNVRAVLERYKAAGIRRIVALRGDLPSGMADPGEFRYANELVEFI
RRETGDWFRIEVAAYPEYHPQAKSPRDDLLNFKRKVDAGANSAITQYFYNADAYAHFVEA
AQALGVSVPIVPGVMPIANFSKIARFSDACGAEIPRWMRRKFESLGDDAAAVRAFGLDVV
TELCERLLAQGAPGLHFYTLNQAGLTTTICQRLGL
>A0A6M2BSJ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Solimonas terrae|TrEMBL
MNNQDLHFSFELFPPRTPQGWEKLPQLISELANVQPAFFSVTYGAGGSEQNGTYDTIIKV
IEQTGIEAAPHLTCVGSTRANIAALLEQYKAAGVKRIVGLRGDLPATAMSNAAPGEFRYA
NELIEFIRATHGEHFRLEVAGYPEMHPQAANPQADFDAYVRKVKAGAHGVVTQYFYNADA
YFDFVERSERAGLDVPVVPGIMPILNTAQLLRFSAACGAEIPRWIRLRLEQLQDDKPALQ
AFGLDVVTRLGETLLKNGAPGLHFYTLNQSEPTLRLWKNLGLPVPHGPGTDS
>A0A5B1M7X7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides antri|TrEMBL
MTTGRGRSLGEIIREGERSFSFEFFPPKDDAGEEQLWNAIRALEPYRPTFVSVTYGAGGS
TRDKTVSITGRIARETSLVPMAHLTCVGHTREELEAILDSYVAEGVYHVMALRGDPREGP
RAEWTPTEGGLNYALDLVELARSRGDFRIGVAAFPEGHPSAESLDADADVLVAKANAGAE
FAVTQMFFRASDYFGLVERVRARGVDIPILPGIMPILNLNAIRRQGELIGTSVPDEIVDR
ITAAGPEPVAVRAEGIKLAAELCEELLAGGAPGLHFYTLNRSKATLEIFEALRITV
>A0A4S1FPF2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M4B.F.Ca.ET.143.01.1.1|TrEMBL
MTIRQRDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAK
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDKNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAKPVFDLDSMSLLETCRIMRDNGKFLSGRKLTTPPQIFL
GAAVNPFAPPFDFRPIHLGKKIAAGAQFVQTQYCFDVPMFKTFMQKARDLGHTEKVFVLC
GVGPLASAKTAKWIRSNVPGIHIPDAIIKRLEGAQDQKKEGKQLCIDIINEVKEIPGVAG
VHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDHILHDEITETQVDMVK
TAH
>A0A5C7SZU4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodoferax sp|TrEMBL
MADQRLPISLEFFPPKTPEGADKLRAVRQQLYALKPEFCSVTFGAGGSTQDGTFSTVREI
LAEGVDAACHFSCIGATQDTVRQNLATLQSMGVKRLVALRGDLPSGYGLGGAFQYASDLV
AFIRAETGDHFHIEVAAYPEMHPQAKSPQSDLQAFAAKARAGADSAITQYFYNADAYFRF
VEEVDALGLNVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRLRLQSFGDDTASIKAFGL
DVVTSLCEQLVAGGAPAIHFYTMNQSAATLALCERLGWTA
>A0A524B3V6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MKPEISIEFFPPQTPEGIEKLRKVRGELASLNPQFFSVTYGAGGSTRERTFAVVKEIAAE
GFDAAPHLSCIGSTRESIREILAEYNEAGIKRIVALRGDLPSGMAETGEFRYANELVEFI
RAETGNHFSLEVAAYPEWHPQARSPKDDLDAFVRKVKAGANSAITQYFYNADAYFHFVDE
AKARGVDIPIIPGIMPIAGFTKLARFSDACGADIPRWMRKKFESFGDDSDSIRAFGLDVV
TELCERLLKGGAPGLHFYCMNQSALTTEICRRLG
>A0A2N1L282|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trichoderma harzianum|TrEMBL
MDKITEKIAALPPDGEYFSLEFFPPKTAMGFSNLRVRLQRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREIGLTTCLHLTCTNMSQALIDQALEDARALGIRNILALRGDPPRAEY
RDADEPDQTASEEFTWAIDLVKYIRKKYGSYFCIGVAAYPEGHGDGSHPEGQSFEHDLPY
LVEKVQAGADFIMTQLFFDIEAYEKFETTLRNHPSGAFKTIPILPGLMPIQSYAMIKRTA
KLSHAKIPEETMARLNAVKGDDEKVKMVGVDIVSELIGQIREIKSRTPGPKGFHFYTLNL
EKSISFILERTKLIPDVPDDEEAVVDEPVAAAAQLVVPKISVNGNVPPRSSSHARTGRRQ
SSVGSDPHNRVIVGRAATHPEWEATSTEAGIPAESVNTRANTLAISEGEGALGREATWDD
FPNGRFGDARSPAYGEIDGYGVSIHMSVTQAVRLWGHPKVASDINDIFVRHIRGEISAIP
WSEEDLLPESSIIKSKLEAMNRKGWWTVASQPAVNGLPSTDSTFGWGPASGFVFQKSFVE
FFIPSADWKILYDKLTSAEVEEVVCFYASNAKGDFISSDASGGSGRAVMSASTNAVTWGV
FPGKEIVTPTIIEEVSFRAWSEEAFDIWAEWAKVYGRGSDSQKLLDEIKEDRWLVNIIHH
DYVDTEALWRLLIE
>A0A431KA50|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodocyclaceae bacterium|TrEMBL
MRRRAHEENPVPNKTPFSIEFFPPQTLEGVEKLRATRAQLAVLQPEFFSVTFGAGGSTQA
RTFETVFEIQREGHQAAPHLSCIGSTREHIREILLRYKDEGIRRIVALRGDLPSGVGDPG
ELRYANELVEFIRAETGDHFRIEVAAYPEYHPQARTPQDDLLAFKRKVDAGADSAITQYF
YNLDAYLHFRTECERLGVNVPIVPGIMPIVSFSKLARFSDACGAEIPRWMRRKFEAFGDD
SESIKAFGLDVVSELCAKLIEAGAPGLHFYSMNQAGPTIALCERLGIGQVNNRQG
>A0A2P8DKT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Murinocardiopsis flavida|TrEMBL
MGTLAELINDPSPARPIVTAELPVVDGGGLDAVRTRLARIAPYVDAVNATDNAAAHAHAS
NVAIAIALRQAGTEPILQLVCRDKNRLALQADIAGAALHGITTVCCLTGDDVTAGDEPEA
RRVFDMDAPQLIRTAATMANGRYLSGRAISPAPPLLIGAVENPAAPPFAYRVRRGLKKAA
AGARFLQLQICYHPERLAAFTDLAARTGLTPKVALLPTVCLVKGARALRFMDANVPGISV
PAGLIEQIETAPDPREAAYQLALEQARHALALPGVRGLHLADFRHDDSVARLCADLGLPM
LRQVSDDPAVAV
>A0A3R0XBZ6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella dysenteriae|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRTLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2T3D4J7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ensifer sp. NM-2|TrEMBL
MTALIQHGSALFRDYSLEITGKDIWQIEAAKSEIPAGTPINIAYLGNESHAQRIEAAARI
RQWGFEPVPIISSRRLRSVQDRDELLTGLISAARPARFMFVGGDPSSPTGPYKDSLDLIA
GGIVADHGIVNVGIAGYPEGHPKIDQARLWEALGQKTELLKARGCSVEITTQFGFDADAV
VDWIAQVRARGIDAPIRIGVPGPADVKRLLRFAAQFGVASSAAIVGKYGFSLANLVNKVG
PDRFMSRLAGGMAGRDLGTVMLHLYPFGGIADTVAWAARAAGRQTNESVGALDRPRYY
>A0A371BUG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. RT-1|TrEMBL
MTGAASERVTRSGTKPHTRASREVRSLPTRLEIIPTEGITAGVRAHVPAGSTITVTCLPH
HGIARTMQTALQLAGMGYSVVPHLAARSIGSRGQLEAALRDCRDAGIREVFAIGGDASEA
AGPYSNSLQLLEDIMELSGGDISAGVAGYPEGHPHHGELQMLDALLEKQHLASGVTTQMC
FSVPRISWYAETLRREGVQLPIWAGVPGAVPRAKLIALAAKIGVGPSLKFLTRQGPLGRR
LLSGSSYSPLPILDQLRDVPEIAGIHLYTFNSLGHGNPQATS
>G6FYM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fischerella thermalis JSC-11|TrEMBL
MLDTQNPTSLTSFRTAAKAGQFLITAEVAPPKGGNPEHMLKMAATLKGRVHAVNITDGSR
AVLRMCPVVASAILLQHGIEPICQIACRDRNRIGLQADLMGAHALGIRNILALTGDPVKA
GDHADCKGVFDLESVRLLQVIQKLNHGVDYNDKPLNDGALDLFPGAAVDPQCPSWSGLQK
RFERKLEAGAQFFQSQLITDFEILEKFMDKIAADCGKPILAGIFLLKSAKNALFINRCVP
GVNIPQHIIDRLAQAKDPLEEGMKIAAEQVQIAQQLCQGVHMMAVKREDLIPQILEMAGV
TPVNQMVSL
>A0A531GAS2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKSDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVIQEFAGMGVTRFVALRGDPAEGVGA
SYRPHPDGYANGAELVGAMKGAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>G8P3N2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lactococcus lactis subsp. cremoris A76|TrEMBL
MTSDSKILSFEVFPPTTQVGSSHLVKTLDSLRALSPDFISVTCSNNNYENIADTTIKFAD
YVNNTLNIPAVAHLPAAYLDKTQVIEILERLREKQIMKVLALRGDISDEATKKDFKYASD
LVKFIKDYDSSFEVLGACYPDVHPESINRISDFHYLKEKVDSGSDKLITQLFFDNNSFYD
FQERCAIAEINVPILAGIMPVINRNQILRLLKNCNTPLPAKFIRILEKYEHNHVALRDAG
IAYAIDQIVDLVTEDVAGIHLYTMNNSETARSIHSSISSLFKINT
>A0A024Q9Q2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Virgibacillus massiliensis|TrEMBL
MDLLAELDKRILIGDGAMGTLLYSYGVDHCFEALNLSHQEQIAHIHESYIHAGADLIQTN
TYGANYMKLARYGLEDQVKKINTEAIKIAKQAANEETFVLGTIGGIHGTQTLQAKTDEIK
RSFREQLYCQLLEGVDGLILETYYDLEELITVLEIARDETNLPIIANVSMHEPGILQNGI
LLPDALKRLENTGADIVGINCRLGPFHMLESLKDVPLLDKAFLAAYPNASLPAYRDGKLI
YEDEPNYFKNCATDFRNEGIRLLGGCCGTTPAHIKAAADAIKHTKPIKEKIVPVKPRPIK
VSEQKEQSESGLIDIVQQRHAVIVEFDAPKHLDTSEYLNGINALNDVGVDAITLADNSLA
TPRISNIAVAAKIQQEIGVRPLVHLTCRDRNLIGLQSHLMGLHTLGIHEILAITGDPTKI
GDFPGATSVFDVTSFDLIKLIKQFNQGISLSGKSLKKPTNFQVGAAFNPNVAHIDKAVKR
MERKMERGADYFLTQPVYSKETIVALANKTKHIDKPIFIGIMPLTSSRNAEFLHNEVPGI
KMPDVIRERMKAVADDKQRSIDQGIQIAKELLDTALEHFQGIYIVTPFMRYDISIELVTY
MQARVQLLSTSKMT
>A0A4Z0DPX5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia proteamaculans|TrEMBL
MSFFHANQREALNQSLAELNGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLREIATDYWNSGIRHIVALRGD
LPPGGGKPDMYATDLVALLKDVGDFDISVAAYPEVHPEAKSPQADLINLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTSMFE
GLDDDAETRKMVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVIA
>A0A7Y6LHZ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. KAI 90|TrEMBL
MALGTASTRTDRARTVRDILAAGKTTYSFEFSAPKTPKGEKNLWSALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHLTAVNHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVPHPQGLTYAAELVELIKESGDFCVGVAAFPEMHPRSADWDTDVARFVD
KCRAGADYAITQMFFQPESYLRLRDRVAAAGCDTPVIPEIMPVTSVKMLERLPKLSNASF
PAELKERILAAKDDPAAVRSIGIDFATEFCARLLDEGVPGLHFITLNNSTATLEIYENLG
LHHPPRA
>A0A1W9LZN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium A2|TrEMBL
MRSGSNLERVLKSGQFAVTGELGPPKNSDPEVVRKKARILKGHVDAVNITDCQTAIVRMS
SIGAGLIAQQEGLEPVIQMTCRDRNRIGMQSDLLAASALGLKNLLSLTGDHQKFGNHPGA
KGVFDMDSIQLLGMVRTMCDERRFQCGEEIKGEPPRFFLGAAANPFAYPFEFRAVRMGKK
ISAGADFIQTQIIYNVEKFARFMEMARELGLTEKAYILAGVTPPKSLGMAQYMKKSVPGM
DVPDSIIQRLRDASDKQEEGIRICVDIIEQVRAIKGVAGVHVMAIEWESAVPEIIARAKL
GPRPVFADTAVPEPVRAETIELRSTAAPAVDTETLLAKARAEAEEIIAAARNEAARMAAA
APAARMTTPALAVISDDAGEHEMNENDRQLALESLKHGLDALRRAYGLNDDQFAALMNFA
GAEAILRKEPPATTAAPVAAVVAPAPTPAAAPAAPAVDSAARAEAEAKAKAEAKAKAEAE
AKVKAETEAKVKAEAEAKAKAEAEAKAKAEAEAKAKAEVAAKAAASAPAAAPAAPAASTV
AALAREPKAFAERTAKVPASSFKQAYNGTIREVVMGNGDKSVTVGGSAVLPFHLFEGAMP
RRPLIAMDVLDMKPDNWPSTLSRHFADVLGDPVAWAKKCVNDYQAEAITISLVSTDPNGA
NRSSAEAAKDAAAVVAAVEVPIIVWGCGNNEKDTATLRELTAIIGDKKVCLAPLEDANYR
AIGATAMAFQHPVVAASPIDVNLAKQLNILMQNLGVQLDTVLMDPSIGALGYGIEYTYSV
MERIRLAALTQQDD
>A0A1W9MG41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Desulfobulbaceae bacterium A2|TrEMBL
MSLSFRESLGRPGQFTLTYELVPGQGSGSRQVERLLAFVLRAQADGRIKALSITDNAGGH
PSLAPSSIGADVQALGLEPLVHFSLKDKNRNQIESHIFFYHRQGFHSLLVMGGDYPGRGY
HGQAKPVFDLDSVQTLQLFHDLEQGQYRSGSSIQQELSALSFFRGCVVSPFKIGQAEQLW
QYGKLLRKIRAGAQFIVTQLGYDLRKFDELLRFLRQAGIETPVLANVFIPNLTVARLMSR
GQVPGIVFPPALLRAMEDEAQAGRANEARLQRASMMIATLRSMGYAGVHLGGNGLDFDKV
ARVMDMAEAMHGNWRDLGREAHFPVPGTFYLYEDDPAGGNGPQPRPLRPPSGPGPAWYFN
HALHGLLFEEDNPCGRGLGRLCRHAYGRPRLTRLLILLELLSKVPLFGCHLCGDCTLSES
AYLCPQSGCPKRLVNGPCGGSREGRCEVHPERPCFWVRVYECGRRPADAAELGQAPSLPP
KDWSLSRGSSWINFFTGRDHRKKLINSNLGKDLSNML
>A0A532BRD2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MIGRQPDENPAGIHLPLDPLPGHTSRGRLERVLRRGEFAVTTELNPPDSADPEDVYNRAR
IFDGWVDAINAVDASGANCHMSSVGICALLTRMGYAPIMQIACRDRNRIAIQGDVLGGAA
MGVANMLCLTGDGVQAGDQPGAK
>A0A527JAT5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKSDEMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTISRILQETSLTPAAHMTCVDAARHEVDAVIQEFADIGVKRFVALRGDPAAGVGT
AYRPHADGYANGAELVGALKSAGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFD
GLQNDPQTHALVASAVAAEQVLDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAEVA
GSAAA
>A0A528F9W5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
VDNGATRAITQFFFDNDLYERYVERARRAGIYIPIVPGILPIHNFTQVGNFSARCGTLVP
AWLAERFDGL
>D8FDW3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|delta proteobacterium NaphS2|TrEMBL
MSELKAGSNLEKVLRAGHFAFTGECGPPQGANVEHLIEKGNHLKGVVDAVNVTDNQTAVV
RMSSWAASLILLEHGIEPNFQMVCRDRNRLAIQSDILGAYSMGLRNMLCLSGDHQSFGNH
PESKNVYDIDSMQLIHTVKTMRDEGKFLNGSDVDVAPKFFIGAASNPFAEPFDFRVYRLA
KKIDAGADFVQTQCIYNMDKFREFMKRAVDMGLHEKCYILAGVTPMKSVGMALYMSKQVP
GMDVPESLIKRLRGAGKGKVAEEGIKFALEQIEEFKEMEGVAGVHLMAIEWEHKVPEIAE
RAGVLPRPVV
>A0A511QMJ4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Vibrio superstes NBRC 103154|TrEMBL
MGYTHASHIDALNQNIAELSDNINVSFEFFPPSSEKMEETLWNSVHRLKTLQPKFVSVTY
GANSGERDRTHSIIKEIKSQTGLVAAPHLTCIDASREELITIADDYWKNGIESIVALRGD
IPPGGGHPDMYASDLVELLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCAATGIDVEIVPGILPVSNFKQASRFAAMNHVKVPGWMAQQFE
GLDDDPTTRQLVGASQAIDMVRTLSREGVKDFHFYTLNRAEMTYALCHTLGVRPQQVAV
>A0A3E5D4B3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus anginosus|TrEMBL
MSSQSPSLSFEVFPPNLAVGNEKIMAALKEMQDLAPHFISVTASNNKFNIEETTVRLADF
IRNDLHIPTIAHLPAVYLTKEMVTETLTALDKVGVHKVLALRGDILPDVEPQKDFVYATD
LIEYIKKEAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNERFYD
FQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIYLPRKFCSILDKYEHDPESLRAA
GLAYAIDQIVDLVTQDVAGVHLYTMNNSDTAHQIYQATHTFFDK
>A0A530HB26|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
VGALKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRAITQFFFDNDLYERYV
ERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFEGLENDPQTHALVASA
VAAEQVLDLVERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEATGSAAA
>A0A0A7I6Q1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium kashiwanohense PV20-2|TrEMBL
MHSPMFSLEVFPPKRTSPVGTIYDTLDGLQGLDPDFISVTYGTGKSSDRTLTARIAHTVS
EYGIPSVAHLTAQYLNRDDVDQALDMFEQAKVSGVLALRGDRIDGAEPAGVFDHASDLAV
YIRQQRPGMKIYGACYPEKHPQAATLEEDIDNLKKKVDAGVTHLISQLFYDNEDFLRFLD
KARTAGIDVPIEAGIMPVMNAKSVLNMSSKCQSKIPEKLGIMLDKWGSDKALLKEAGIAY
ASEQICDLVARGVDGVHLYTMNHPCVSRRIWSNVKPFFV
>A0A4U9ZVV2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus anginosus|TrEMBL
MSSPSPSLSFEVFPPNPAVGNEKIMAALKEMQDLVPHFISVTASNNKFNIEETTVRLADF
IRNDLHIPTIAHLPAVYLTKEMVTETLTALDKVGVHKVLALRGDILPDVEPQKDFVYATD
LIEYIKKEAPHFEIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLLTQLFFDNESFYD
FQDKCILAGIEVPIHAGIMPILN
>A0A0R1NC73|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Schleiferilactobacillus perolens DSM 12744|TrEMBL
MGETLDVLSGLHPDFVSVTFGANGTIQQTGLATASYIRKTYGIETVAHLPAAQLAAPQIH
QLLADLKNHGIENILALRGDIPASGRVSNDFPHACDLVRYIHECGDFNVLGACYPEGHPE
SPDLPTDIHYLKDKVDAGTSQLISQLFFDNQVFYDFVDQARATGIQVPIEAGIMPVINQH
QIERMATMSGVALPEKFTTMMARFQDNPAAMREAGIAYAVDQIIDLLVHGVDGIHLYTMD
NADVAKRIFAATEQVLHA
>A0A528WQQ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
VQTQYCFDVPMFRTFMQSARDLGHTEKVFVLCGVGPLASAKTAKWIRSNVPGIHIPDAVI
KRLEGAQDQKKEGKQLCIDIINEVKEIPGVAGVHVMAYRQEEYVAEIVDESGVLKGRQPW
KREMRRDDQVVADRLDHLLHDEITETQVDMVKTAH
>A0A527R9W2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDDMEARLWDTVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHQVDAVIREFADFGVKRFVALRGDPAAGVGT
DYRPHPDGYANGAELVGAMKSVGDFDISVSAYPEKHPESPDFATDIDMLKRKVDNGATRA
ITQFFFDNDLYERYVERARRAGIYIPIVPGILPVHNFTQVANFSSRCGALVPAWLAERFE
GLENDPQTHALVASAVAAEQVLDLIERGVGDFHFYTMNRADLVFAVCHMIGIRSHEAEAA
GSAAA
>A0A527DAP4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWETVTRLEPLKPKFVSVTYGAGGSTR
ERTARTVKRILTETAIPAAAHLTCVGATRDEVDAVIQDYNSIGINRFVALRGDPASGVGE
PYRPHPGGYENGAELVAGLKAIADFDISVAAYPEKHPQSPDFATDIEMLKRKVDNGATRA
ITQFFFDNDLYERYVERVRRAGIYIPIVPGIQPVHSFRQVANFSARAGAHVPGWLAERFD
GLDRDPQTHALVASAVAAEQVMDLVERGVGDFHFYTMNRADLVFAICHMIGIRSHEAETA
GSAAA
>A0A2E4IJN8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidiferrobacteraceae bacterium|TrEMBL
MATDTAVDTLPDLKSGSNLEKVLAAGHFAVTGELGPPKHMDTNVVDRKIDLLKGVVDAAN
VTDNQTGIVRLSSIATGIYMAQHGLEPVIQMTCRDRNRLAMQSDLMGAYIHGIRNVLCLS
GDHQSFGNHPGAKNVQDIDSMQLIRMLQEMRDKNQFQCGDEIKGGGPKLFIGGAGSPFSE
PISFRPLRIAKKMAAGVDFIQTQMIFDMDIFRQFMRRLVDLGVTEKVHILAGIGPLKSSP
MARFLNENIPGIVIPEDLLKRMDSAVQGISEDDKEARRDAWRAEGQDICIEQIEELQQIE
GVSGVHIMAIEWEAAIRPIVERAGLLPRPIF
>A0A6N9HA96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Brevibacterium rongguiense|TrEMBL
MPERATRPALSFEVIPPRTAAAHRALPALIETIGGYRPDYVAITSSPTSGWSQGTADFVS
ALAADPRLRPLAHLTCTGAPRPLLEAWIDHFVAAGVRGFLAIRGDLPPGVRAPQPGHLRH
ADELVSLIRTAEARQAARFCAGRLAVGVAAYPGGHPESPDRDFDIDVLLAKQRTGADFAL
TQLFFDPRDYADLVRRARLAGVTLPIIPGIFPLTSPRRLERMGRLAGLRPPPQLARALAA
APTPAAQRDIGLAATAALARAVLAAGAPGLHLYTFNDAEVTGELLDRLDLAPAAPAAALR
PI
>A0A7U9LBW9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSKDRRYSFEFFPTKTDAGHEKLLATARQLAGYNPDFFSCTYGAGGSTRDRTVNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLQQYQAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREETGSHFHIEVAAYPEMHPQARNFEEDLVNFVRKANAGADSAITQYFFNADSYFY
FVERVRKMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDSASIQAFG
EQVISDMCERLLQGGAPGLHFYTLNQADPSLAIWNNLQLPR
>A0A846WF34|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardia coubleae|TrEMBL
MVSNTPSVVQSLRTHSGTGVPFSVEFNPPRDAAGEARLWRAVREFERMHPAFVSMTYGAG
GSTRDRTVRITGALAQETTLLPVAHLTAVGHSIAELRSLVGSYADSGICNVLVLRGDPPG
DPLGEWRKHPEGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLDHDTRHLCAKLRAG
AEYSITQMFFDVEHYLRLRDRVIAMDPAEGAKPIVPELMPITSLRTVARAEELSGRPVPA
DIVARLTRAAGTGPEEDRAAVRAEGIQIATEMAQRLIDEDAPCLHFITLNFAKATSEVLT
NLGYGVTAAPLSA
>A0A6M0PB54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Weizmannia ginsengihumi|TrEMBL
MGLIERLKNEILIADGAMGTLLYSYGIDFGYEELNVTNPSIIERIHRDYLEAGADIIQTN
TYSANAIKLARYGLENDVKKINNAAVSIAKKSISSSEQYVIGTLGGIRGIRKNSASMDEI
SAAFTKQLDILLEGNLDGFLLETYYDFEELTNVLKIARSMTDLPIIAQVSMHEPGFLQNG
LPLNSALEQLEILGADVIGVNCHLGPYHTCQAFDQVTLPKKAFLSAYPNASLLDVVDERI
VYKSTADYFGKLAVELRNQGVRLIGGCCGTTPDHIAAVKKALKGLLPITEKEVEHPRESI
LIEDHAPTPPSLVEKVKKQRSVIVELDTTKHLETTTFFKGAKSLQEAGIDALTMADNSLA
SPRISNMAMATLLQTNHNIRPLVHITCRDRNIIGLQSHLMGLHALGIHDILAITGDPSKI
GDFPGATSVYDVSSTELLQLIKQLNEGISFSGKPLKTKTNFTVAAAFNPNVRLLDRAVKR
LERKIKAGADYFISQPVFSIEKIEEMYEATKHLSTPIYIGILPLTSSRNAEFLHNEVPGI
QLSEEILMRMKAWEHDKVQAEREGIKIAKELIDVAARKFNGIYLITPFLRYHLTTELVTY
IHDLDATITKGDANDVQSISH
>A0A329QQ49|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus taichungensis|TrEMBL
MKADLRSVMQERVLIGDGAMGTFLYQMGFPVGISYEELNLISPEVVADVHRRYRDAGTEI
HETNTYSANYDKLSKFGLESKVEDVNRAGVRIAKEVAGANGYVLGAVGSIRGGKRTNVST
SELKRFYQQQIFALLDEGVDGILLETFYDIEEMDIALLQARKLSDLPVIGQFAVEDVGHT
LDGYTMPEAFRIMREQGADVIGFNCRSGPNGIMRAMETVSGRIGVPMSVYPNAGAADYVD
GQFRYGASPEYFGQTAVQFADLGARIIGGCCGTTPDHIAAIAQALVEYTPVPILEPDPSE
SKPRIILHENVDERSGRGGQPTIVDLVKQRHTVIVELDPPRDLDIAKFMKGAETLKAAGA
DALTLADNSLAVTRMSNMALGHLVQDRTGLRPLVHIACRDRNLIGTQSHMMGFDALGINH
VLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNDGVSFSGKPLKQKAGFVIGAAFNP
NVKHLDKAVQRLEKKIASGADYIMTQPVYDPQLIVAMHEATKHLDVPIFVGVMPLASGRN
AEYLHNEVPGIQLSDEVRSRMAGLEGEEGRAMGVKIAKELLDVATKHFKGIYLMTPFMFY
SMTAELTQYVWEKSEHQCPTCFNPNNQLQ
>A0A7K0BHG3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. LMO6|TrEMBL
MKVTEHIQNANGKPLFSFEILPPLKGQNIQSIFDSIDPLMEFNPPFIDVTYHREEYEFKE
LANGLLQKKVVKKRPGTVGICAGIQNKYEVDAIPHILCGGFTKEDTENLLIDLDFLGIDN
VVALRGDAVKSEIYFKPEKEGHSYASELVTQISNLNNGIYLDEDLQNSTKTDFCIGVAGY
PEKHMEAPSLDSDIHFVKQKIKNGADYIITQMFFDNKKFFDFVKKCRAAGITVPIIPGLK
PIATKKQLNLIPHRFSIELPDDLIMAVVKAKDNDAVKQIGIEWCTQQSKELVAAGIPVLH
YYSMGKAENIKTIAKDIF
>A0A5E8UXL8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseibium alexandrii (strain DSM 17067 / NCIMB 14079 / DFL-11)|TrEMBL
MTDSSLLANGRLPASTEMSPKQVVEKTELLATIPAGSQVYVTDLGNAPEDTIVAAAKTLT
DKGLIAVPHMAARRYASAADFERRITRLTQEAGVKEVLAIAGEADKAGPLTSSVALLETG
LFDTLGIQKIAVAGHPEGAPDIKPDVIKSFLMRKHELAAESDAEFRIVTQFGFDPHQVSV
WLDEIRGWGNQFPVHIGVAGPAKMTTLLKFAAFAGVENSLNFLKKRGGAVVSMLAGYDPN
TMVEPLEARITSQPDSQLAQIHVYPFGGVAKTAEWLTSRGSWSFQTSSTSLTANESA
>A0A2R4BIJ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thauera aromatica K172|TrEMBL
MYSVRLWSVRHARRLKNLYALFSRFAPLAAPVARTLGVERTASILRPLEQQAKGFLFDCR
MCGQCVLSATGMACPMNCAKEMRNGPCGGVRPDGHCEVKPGMRCVWIEATDGTKQISADH
KAHPTPLLPAVDQRKRGSSTWIQVIHGGKDPAFQPPIREKTTPEAEESPLETACRSGRFV
VTVEIAPPDSADPSVLLARAERFRGLVDAMNITDGAGGNCHMSSVAASAILAHAGFNPVY
QVACRDRNRIAIQGDILGAAALGVKNILCLTGDDVSQGDHPQAKPVFDLDAVSLLHVARG
MVDRGEFVSGRKLESPPRLFIGASCNPFVPPFTDRIANLEKKIVAGARFIQTQFCFDLPL
LQAFMAEVRARDLHRQARIIIGVGTLSSAKALRWMGTHVPGVHIPEAVLQRIGNAADQKA
EAMQVCLETIGAIRGVEGVAGIHLMGHKNDETLVELIRRAG
>A0A3N4J0X5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Choiromyces venosus 120613-1|TrEMBL
MDRMNQLGPQFIDITWNAGGRLSNLTCEMVNVAQSVYGIETCMHLTCTGMPKSKVDNALK
EAYKAGCTNILALRGDPPRENEKWEADPHGFRYAKDLVKHIKANYGNHFDIHVAGYPEGS
DDGTDPELLLKHLKEKVDAGASSIITQMFYDVDIFLDWVKKCRDIGITVPIIPGIMPIHT
YAAFMRRATWTKCHIPEKWLQLLEPVKNDDVAVRDIGRDLMVEMCHKIVDAGILHLHFYT
MNLATATRMCLEGLGLVPSLEERTKALPFRPSLGLNRKEENVRPIFWKNRHMSYVQRTQE
WDEFPNGRWGDSRSPAFGELDTYGIGLRGSNEANIKIYGYPKTIRDLCELIKKYLTGNLP
SLPWSEGYINSEADAIRDELLKLNERGFLTINSQPAVNGVKSTHPVYGWGPKNGYVYQKS
YLELLVSPEQLTELITRIERNPDLSYHAVDKHGTLKTNSSEGPNAVTWGVYPGKEIIQPT
VVETISFLAWKDEAFRLGDDWAKCYEADSVSRHLIQEVMDNWFLVNIVDNDFHQSESIYR
LFDGMEVPNMDESLMTA
>A0A2M6ZFF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Desantisbacteria bacterium CG07_land_8_20_14_0_80_39_15|TrEMBL
MSTLKDTLKEGRFVVTSEVGPPKGTDIHKLMEEAEILRNKVIAINVTDIQSAVMRLGSMA
VCHLLKEKGLEPVFQMVCRDRNRLALQSDLLSASVLGIENVLCLTGDYPTLGDHPQTKPV
YDLDSVQLLAAAKGLCEGQDMAGNALEGKPDFFLGAVVTPGTDPVEPQIIKMEKKIKVGA
QFFQTQAVYEVDKFAIFMEKVKHFGV
>A0A4Q4ZDI8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides guangzhouensis|TrEMBL
MAHTTQRGIGRLIREGERSFSFEFFPPKDDAGEAQLWQAIRDLEPYHPTFVSVTYGAGGT
TRDTTVEITGRIARETSMVPMAHLTCVGHTRAELEAILDAYEGAGVANVLALRGDPREGP
RAAWVPTEGGLTYARELVELAAGRFSVGVAAHPGGHPAAESLQRDVEVLREKQAAGAEFA
ITDMVFRAEDYFSLVERATAVGVDIPILPGIMPILNLGQVKRMAELSGHPVPAEVVARLE
QYDGDPAAVRAEGIAMAAELCDALLDGGAPGLHFYTLNRSKATREIFAALRITV
>A0A1M6UYL1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maribacter aquivivus|TrEMBL
MKVTDHITNAKGKTLFSFEIVPPVKGRNIQELYKNIDPLMEFNPPFIDVTTSREETIYVK
KEGLLDKRTTRMRPGTVGICASIQHKYNVDTVPHVICGGFTKEETEYMLVDCHYLGIQNV
MALRGDARSEQKYFEPTDGGHPFAINLVKQIQDLNCGKYLHESIESEHCSEFCIGVAGYP
EKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNKKYFEFVEAAKNIGITVPIIPGIKP
IAVKRHMQLLPQVFRIDMPQDLIEAVDSCATNKDVRAVGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIKAIAEALF
>A0A5E7CUB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKADLRSLLTQYKAAGIKRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFENDLQNFVRKANAGADSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISTMCEELLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A3D4RSC0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chromatiaceae bacterium|TrEMBL
MNTQGTDLATFSFELFPPKTTEGMDKLKLAVEQLNAVRPRYFSCTYGAGGSTRERTFETV
AWLRQQAIDTAPHLACIGSDKDEVRNIARHYLEQGISRVVALRGDLPSGMGRLDSNTFRH
ANELVSFLRQEFGDQFHIEVAAYPEIHPQAASAKIDLVNFKRKVDAGANAAITQYFYNAD
AYFRFVDDCADAGIDLPIVPGIMPITNYTQLARFSDACGAEIPRWIRKRLEGFGEDKDSI
RAFGHEVVIALCQDLLEGGAPGLHFYTMNQPGPTLRLWEELALSHADQ
>A0A4Q6DYC9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacteriaceae bacterium|TrEMBL
FKEHENGLLEKLSYRKRPGTIAICAAIMNKYKVDTVPHLLCGGFTKGETENALIDLQFLG
IENVLVLRGDARRGDATFVPTTGGHCYATDLLQQVVDMNNGKYLHEDYDGIEKTDFCIGV
AGYPEKHFEAPNLKTDFKYLKQKVDNGANFIVTQMFFDNQKYFDFVNGCRANGINVPIIP
GLKPITNSKQLVSLSKTFFIDMPEDLCDTVHACKDEKAVREAGIEWMINQCKELIAFGAP
VLHFYTMSNAGPTKRIAEAIF
>A0A1G5VPA8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Butyrivibrio sp. INlla18|TrEMBL
MKIIDILNSKDVTLSFEVFPPKTDAGYAAVEKASAEIAALKPDFMSVTYGAGGGTSQNTA
NIAANLQNKYGVDVIAHLTCVSSTKEYVDSMIDAYKEKGIENIMALRGDIPKEGRVCYDY
DHAYQLIHDIKSKYSDCCIGGACYPEGHIECARQSEDILHLKEKVDAGCDFLTTQMFFDN
STLYQFLYRIREKGIEVPVLPGIMPITNVKQVSRSVALSGSTIPQKMKIMVDRFADDPDK
LREAGIIYASDQIIDLISNGVSHIHVYSMNKPEIAAGIMRNLATIIK
>A0A448E2T2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGQEKLLATARQLATYNPDFFSCTYGAGGSTRDRTLNTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLNEYKAAGIKRIVALRGDLPSGMGMTSGELRHANEL
VEFIREETADHFHIEVAAYPEMHPQARNYEDDLANFVRKARAGADSAITQYFFNADSYFY
FVDRLQALGVDLPIVPGIMPITNYSKLARFSDACGAEIPRWIRKQLEAYGDDTPSIQRFG
EQVVSEMCERLLQGGAPGLHFYSMNQAEPSLAIWNNLKLPR
>A0A2D6LZ96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MKVIEYLKKANSTLISYEIIPPLRGRSAEPIFELVEQLMPYEPPFIDLTSRAAEIYYDDL
PGGTVKRHIRRKRPGTIGLSAAIKNRFDVETVPHLLCRGFTREETEDALIELFYLGIDNV
LAIRGDETRKQQSGTSGKSYNKFTTDLVRQIKEMNSGKYVEXDLADAYATDFCIGVGGYP
EKHFEAPNLAADLRYLKEKVDAGADYIVTQMCFDNDAFFNFVEKAREMGITVPIIPGLKI
LTRRSHLTSIPRNFFVDIPEKLAQTVMELPEKEAYDAGVAWALQQCQELVEAKVPCIHFY
IMQDASAVTEIVSQIR
>E5AMS9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycetohabitans rhizoxinica (strain DSM 19002 / CIP 109453 / HKI 454)|TrEMBL
MLLVGCNAAQGVRGLRLLVGILWLDPVQHRVVSAERADPWSALYRRALVLTHAGGGTPLF
PIHPMSLPEISFEFFPPKTAEGIDKLRATRAQLAPLKPKFMSVTFGAGGSTQQGTLDTVL
EMAGEGFEAAPHLSCIGASKESLRGILALYRAHGIRHIVALRGDLPSGMGEVGELRYACD
LVAFVRAEHGDWFHIEVAAYPEYHPQARSPRADLENFARKVKAGANSAITQYFYNADAYF
RFVDDVRKLGVDVPIVPGIMPITNYAQLMRFSEMCGAEVPKWIAWRLENFGDDRDAIRAF
GLDVVTAMCERLVVNGAPGLHFYTLNGAAASKAICERLRV
>A0A5E6P7P4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas fluorescens|TrEMBL
MSQDRRYSFEFFPTKTDAGHEKLMATAKQLASYNPDFFSCTYGAGGSTRDRTINTVLQLE
SEVKVPAAPHLSCVGDSKDDLRGLLTQYKAAGIQRIVALRGDLPSGMGMASGELRYANDL
VSFIREESGDHFHIEVAAYPEMHPQARNFEDDLQNFVRKANAGANSAITQYFFNADSYFY
FVERVRAMGVNIPIVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDVKSIQAFG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A2E3DT75|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Marinimicrobia bacterium|TrEMBL
MRIRDKIKKPQRPFVAYEILPPREKDGTLNSYAETISSLLSQTHIDAINIPEVHDEIGRG
DRPISNQDRGEPRKFGMLLQDIVGIEAIVNRVVVHMPFNKQMKWLEDTYAKYEIDNMIIV
GGESSKQKYPGPTVNDTLYAISNEFNNNIGSIFCGGICIPSRDKESKNLIKKSKSGAEFF
TTQVLCDSDNIIKMIKNYQNRCNAIGTFPRRILLSFAPVSNQKNIDFLKWLGVEIPGDTE
KYLNGRPGSMTERSLDVAIEVLNEILDYISNNNLKVPVGLNVEHIMSYNFQSSVEMLQEL
AKIYREFCIKSQQYG
>A0A087L4L9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Serratia sp. Ag1|TrEMBL
MSFFHANQREALNQNLAELTGQINVSFEFFPPRTSEMEDTLWQSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLDAAPHLTCIDATPAQLRDIAADYWNSGIRHIVALRGD
LPPGSGKPEMYAADLVTLLKDVGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPSWMTNMFA
GLDDDPETRKMVGANIAMDMVRILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAVA
>A0A7C7GFT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirales bacterium|TrEMBL
QIARFTKLCGARIPDRLQARLELLASDDDGAREFGIEQATEQCEELMREGVPGLHLYCLN
RAQSVSGILRNLGLSGA
>A0A7W1UHV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospirales bacterium|TrEMBL
DYICTQLFFDNRDFFDFCERCEVVGIKVPIIAGIMPIVSRKGMARMSELALGARIPAKLL
RAMDRAENDVYAEGVGIHWATEQVVDLIDHKVKGIHFYTLNKSKATLKIYESLGIQSSES
LQHPVE
>A0A2A4GUB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus delphini|TrEMBL
MSRLLNALKNNILVADGAMGTILYSEGLDTCPEAYNLTHPDKVESIHRSYIQAGADVIQT
NTYGANFEKLQQFGLEHQVKAIHQAAVAIAKRAAGPDTFILGTVGGFRSTKQGELSLSAI
QYHTDIQVDTLVAEGVDGLLFETYYDDEELLNAIKQTRQKYDIPIIAQLTASNTHYLVNG
KEINSALQQLVKAGADIVGLNCHHGPHHMKRTFGHIELPNNAYLSCYPNASLLDIDQQTF
KYSDNAQYFGETAEQLIQEGVRLIGGCCGTTPDHIRKIKTAVQGLKPIQEKKVIPIHQKQ
TSEAPKPTRQNLATRVRERPTIIVELDTPKHLDTTKFFQNVKALDDAQIDAVTLADNSLA
TVRVSNIAAASLIKQQYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVHEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGVNTDGDTLKVATQFNIAGGFDPHVSNIKAAVRK
METKIKSGMHYFITQPVFTKEKIVEIYEATKHLDVPIFIGIMPITSYKNALFLHHEVPGI
KMSDDVLAQFEAVADDRQATYELSLSLCKSLIDTVHTYFNGLYLITPFERIDYSLELAAY
SKSITTSHQEAIL
>A0A1I7HR96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alicyclobacillus macrosporangiidus|TrEMBL
MTPVGQSWRARARAGVLVGDGAMATQLHQMGVPIRACCEALCVSRPELVERVHRAYLVAG
ADWIQTNTFGGHRAALARYGMEDQVREINGAAVRVARRAVEHAAEARVGADAGGVDGAHR
TGRTGPVAVFGTIGPALDLVAPGGMEAGHRAWLRGLFEEQAEALLAAGVDGLLLETFPAL
EELLLALEAVRRLTEGPVLAHLSPDAVGITRDGVPVQDAFTALLKAGADGVGLNCRLGPN
GVLRTYEGVARQPGVVYSAAPNAGMLHLVDGDIAYTGDPDYFAAVGEQLVRWGVRVIAGC
CGTTPAHIRKVKQRLQAAEWTGAAAGDPDGCSRECSREAAGPDGAQEGLKAPERVQVRAR
PSGETAEDGRPGRTPVGAGDPAGRGEAAERGVQAGPWAPAGSLAERAKRGRTVVVELDPP
RTLDVRRYLEGALALQRAGADAITLADNSLGQVRVSNMAVASLLKQAGVEPLVHVTCRDR
NLIGQQSHLMGLHVLGIHHVLLVTGDPSRFGDLPGATSVYDVSSIELTKMVKRLNQGIAF
SGQPMKHPSRFVVGTSFNPHVANFDKAMDRLRRKLDAGADFVLTQPLFDVRMFERIARAA
EPFGAPVFAGVMPLTSARNARFLHHEVPGIRIPDEILGRMEAAAPEAAAEEGLSIAETLL
DEAMHCFNGIYLVTPFLRYDLTVRLVQFVRARAGAPLSSRAAEA
>A0A532CUP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MSREPRRLREVLDEGQFAVTIEYNPPKGTNISGVLENAKQLVGRVHGVNVTDNTAAVVRA
GSLSVCRLLYELGHDPVMQMTCRDRNRIGIQSDLMGASMLGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNNGRDMAGNKLDGSTSFTIGAAVTPEADPLGPMLAKFEVKV
KAGAQFFQTQAIYHPEQFASFMKAVRPFKAKVLAGILVLRNAKMAEFMNANIPGVSVPQE
MIDELRAAGPERAEDVGVDIAVRTIKAVRTYCDGVHIMAIKATHRLADIITKAEVG
>A0A1J9QFJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Blastomyces percursus|TrEMBL
MEKISDKIAALPRNANYFSLEFFPPKTQMGSSNLQARLERMSQALRPLFVTVTWGAGGST
AAKSLELAEICQRQLGLTTCLHLTCTNMNRSLVDHALSEAKALGIRNILALRGDPPRSEE
YNIDGEDDSNKDFMYAVHLVKYIRRTHGDHFCIGVAAYPEGHSDESHPEVQDPARDLPYL
VEKTKAGADFIMTQLTYDLEAYKRFENLLRSHESGVFKTIPIITGLMPIQSYRILTRTTK
LSHARVPPSIMARVEEVKSDDESVKRIGVDILCEIVNGLKDIPCPGPRGLHFYTLNLEKA
VAFTVERCNLIPPSSEPSSDSESDLGTAVSMVHGQLNNIVRMSKRRASSINSQPHNRLIV
DRPSDGRGSSQASTTHETQALGAGMPALNPPHRATSLQISEGVGALGREATWDDFPNGRW
GDARSPAFGEIDGYGPSLHVNATVARRLWGYPTTKEDINTIFQRHVSGELHIVPWSEGGT
QDTGGLNAETATIRDELLQLINGRGWWTLASQPAVNGVRNDHPIFGWGPRGEGFVFQKAF
VEFFCTAHDLKTILNPIFENHGHDELAWFATNAAGDFESSSPPTGDGVNDYAGPVDVYLD
SNATAGGTGVNAVTWGVFRGKEIVTPTIIEEVSFRAWGDEAFRIWDEWRRVFPRGSPTEK
LLDQLKSDIWLVCVVGQKYGAGCQSKEAAEAEGKLLWKLLAGWDTEANLANKH
>A0A4U6SRV9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Setaria viridis|TrEMBL
MKVIEKIQQAAADGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA
DLTLDIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK
FVQVEGGFACALDLVKHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATPEAYNNDLAYLK
RKVDAGADLIVTQLFYDTDIFLKFVDDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKTK
IPAEITDALEPIKENEEAVKEYGVHLGTEMCKKILASGIKTLHLYTLNMEKSAIEILKRL
GLIEEFKVSRPLPWRPPTNVFRVKEDVRPIFWANRPKSYIRRTLGWDQYPHGRWGDSRNP
SYGALTDHQFTRPRGRGKKLQEEWAVPLKSVEDISERFTNFCRGKLTSSPWSELDGLQPE
TKIIDDQLVKINQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLD
QLVEKIKAFPSLTFIAVNKYGVSASNIPANAVNAVTWGVFPGKEIIQPTVVDSGSFMVWK
DEAFEIWTAGWACLFPEEDSSSKELLKKVQENYYLVSLVDNDYIHGDLFAAFKEI
>A0A1G8RB54|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankineae bacterium MT45|TrEMBL
MVRTVREALSTSEPTISFEFFPPKTAEDERVLWNTIRTLESLKPSFVSVTYGAGGSNRDR
TIEITERIASDTTLLPVAHLTAVDHSIAELREIVGRFADAGISNLLALRGDPPGADPMAE
WSAHPEGLSYGHELVTLLRELGDFCVGVAAFPFKHPRSSSVEEDTRRFVEKCQAGADYAI
TQMFFDVDDYLRLRDRVLAAGSDIPIIAGVMPVTAIGTIARSEQLSGAPFPRALAEKFER
IADDKKAVRDLGIAETSTMVQRLLDEGVPGIHFITFNRSTATREVWSNLGLAVPAS
>A0A2N0LP24|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|SAR202 cluster bacterium Io17-Chloro-G6|TrEMBL
MKIKDILKITRPVSFEFFPPRAAEGIPAVLETLDELKVYCPDFVSVTYGAGGSTRAFTEE
ITLEAKRTAGVEVMAHLTCVGQTKEEIHEVLKRLDAAGVENIIALRGDPPRGSTEFVPVA
GGFQHATDLLKHVKSNFDFGVAAACYPEGHTESVDLDSDLKYVKLKVDNGADFLVTQLFY
DNCYYFDFVERARAIGIDVPIIPGVLPVLNSSQVRRFTALSGSKIPPALDLLLDKYADND
GSARDMGVEYATTQVRELWDAGVPGVHFYVLNRSYSVSRILDNLQLSGHQQVPGHQQAD
>A0A1C5L3K1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured Ruminococcus sp|TrEMBL
MKMKELFDRGEFVVSAEVGPPKGIHVDELVEEAKTYLKDVHAVNVTDNQSSVMRLGSLAM
CKVLKDAGMDPIFQLACRDRNRIALESDLLSAAMFGIENILCLTGDHTKMGDHPQAKPVF
DLDSVSLLHTVKLLESGVDLGGNELVGEPPKFSKGAVVSPCSDSVDAQLAKMERKVAAGA
DYFQTQAVFEPEKFIKFMEKAKQFGKPVQVGIIIPKSVGMVRFMNNNVAGIHVPDEMIEE
LKADKEKTKAGITGVEIAARIIKECKPYCQGVHIMALGWESKIPDLLKLAEI
>A0A1X7N4J8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritimibacter sp. HL-12|TrEMBL
MPTPRISFEFFPPKDIAGAFRLSDTVRDLAPLDPTFVSVTYGAGGTTRELTHDAVTTIHN
RYGLNVAAHLTCVDASRAETLEIAQSYAEAGITEIVALRGDPPKGQGGFAPHPEGFANSV
ELIEALAATGKFNLRVGAYPDPHPEAGSDTADVDWLKRKIDAGAASAITQFFFEADTFFR
FRDKCEKAGIDAPIIPGILPIENWGGVKKFATNCGAKVPGWLDDAFDKALRDGREDLLSV
AVAAELCSDLIDGGVENLHFYTLNKPHLTRDVAHALGVTPRVALQKVA
>A0A5P9JP78|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. THAF7b|TrEMBL
MTSSNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKIPTAPHLSCVGDTKAELRELLNLYKSAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRAETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKAKAGADSAITQYFFNADCY
FYFVERVRKLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLEAYGDDMQSIQA
FGEQVITEMCQKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A4R6VW11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maritalea mobilis|TrEMBL
MSDTPIFSTPDRLSRQSDKDLAKLDLSFEFFPPKTDKMEARFWETLERLAPLSPRFVSVT
YGAGGTTRDRTTKMVSRIEKESGVKAAAHLTCVGASKEEVNDVVRGYKDAGVSRIVALRG
DPPEGVGQPFQPHPEGYRNAADLVAGIRTIGNFDISVACYPEKHPQSPDWYAEFENLKRK
IDAGASRAITQMFFDNELYLRFVDRARNAGIEAPIVAGIQPIHNFTQIANFAGRCGATIP
NWIAERFAGLEDDPETHALVAAAVAAEQVTELVDRGVTEFHFYTMNRSPLVYALARLLGR
RPEISRG
>A0A2K8PMV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces lavendulae subsp. lavendulae|TrEMBL
MASGTASTWSDRAHTVRDLLASGRSYSFEFWAPKTEKGERNLWNALRRIEAVSPSFVSVT
YGAGGSTRGGTVRATEQIAADTTLTPVAHLTAVDHSVAELRHVIGQFADAGIRNMLALRG
DPPGDPMGPWVKHPEGVDYAADLVRLLKESGDFCVGVAAFPEMHPRSEDWDTDIRHFVDK
CRAGADYAITQMFFDPENYLRLRDSVAEAGCETPIIPEVMPVVGIKQLDRLPQLSTAVFP
ADVKERMLAVKDDPAAVRSIGIEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HQRA
>A0A3A0C2V2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp|TrEMBL
MNREPRRLKDVLAQGQFAVTVEYNPPKGTNLTHVVESAKALLGRVHGVNVTDNTAAIVRA
GSMPVCRVLYEMGHDPVMQLTCRDRNRIAMQSDLMGAHILGIRNILCLTGDYPTVGDHKE
AKPVYDLDSVQVMQLVQGLNQGRDYAGNKLDGATAFTIGGAVTPEADPVGPMLVKFEVKV
RAGAEFFQTQAIYQPDQFKTFMEAVRPFKVKVLAGILLLRNAKMAEFMNANIPGVCVPQT
MIDELRAAGDKHALDAGVEIAVRTIKAVRSFCDGVHIMAIKATDRLPEILAKAELG
>A0A6G7ZHW5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. HDW15A|TrEMBL
MNRSSQAALAEHAPLFAEARGDIAVSFEFFPPKSEAMAETLWRSIETLAPLHPRFVSVTY
GAGGTTRERTHATVTRIARETDLTAAAHLTCVDASRGEVDDVAKAYWDAGVRHVVALRGD
PPETGRGFEAHPDGYANAAELVAGLKKVADFDISVACYPEVHPEADCPESDIENLLRKID
AGANRAISQFFFSADCFFRFRDKVTALRPDVEIVPGILPVTNVAQARRFSGQCGATIPAW
MDDTFEGLDDLPAARQLVAATIAGELCGQLYAGGVRHFHFYTLNRAELAYSICHLLGVRV
R
>N9PI97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. CIP 64.2|TrEMBL
MLSLFAQHLAQDRFCILVEYLCSTQSILPVPQSIAGFPAMMTLADRVQTDEDPAPIEFAQ
HYPETIEKLLHFSGKGRDIAEFETFLDQAEQAGQQNLLLLTGDKLKKHSSGQRLATDRTR
YLESVNAVIAAKKRKTFHIGVAFNPFKYTEAERDAQYFKLHKKIRAGADFVITQLGFDLE
QTKHAQAILALDYPGFPLIACVMPLTLRRAQFMLRHQVAGIVISEHILKVLEQENQGDSA
QAKKNVYARCALQILICKHLGYKGVHLSSCHKQQEQAQLEQALQQYQHLSLTECEQLWYQ
LWQTTTHRVFQPKVEIVRKKVTSAQILKYKNMQLLHGVFFSSNAALQLGRFVFKAAFWER
PKASHLLLKLEHFCKHYAVGCDSCGQCRLSETLYICPETCPKGLANGPCGGTSLDRCEFG
DRECIHSVKARLAKAVGQTELLKTELIPAVSIETRATSSWKNWFKSIEPQNRGKEI
>A0A2K3J2U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon M9B1D|TrEMBL
MAYKSNLQRVLSEKKFAVTAEIGPPKGSDPGKIRKKAELLKGYADAFNITDNQTAVVRLS
SMGGSFILLNSGLEPIMQMSCRDRNRIALQSDVLGAVSVGVRNILFMTGDHQSFGNHPGA
KGVYDLDSIQLIKIVKDMRDLGVFQSGDKILAGIPDVFIGGTANPFADPLDFRVDRLEKK
IIAGADFIQTQSVYNLDKFKMWMDEVYSRGLDKKVFILAGVTPLKSVKMVERMKFHVPGV
DIPDEIYKRMINTPDPKSEGYNVSLELIDEIKKIKGVSGIHITALFWEDIIPKLVRESGF
YPRP
>A0A1V6G7G5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Planctomycetes bacterium ADurb.Bin069|TrEMBL
MTLQEVFAKKTFCLGVELVTTRGLAHHDPAAKVLRLGRDLAGRTEIDWLSITDNAGGNPA
LAAEHLGGLLRDLGAEVLIHLSAKDMNRSALEGRAWALASRGLTNVLALTGDYPVAGFRG
NARPAFDLDSVTLLAMLADMNAGMEIAAPGRAAVTLEPTAFYPGVAVSPFKAQAAELLGQ
YLKLERKIVHGARFIITQVGYDARKWDELRLHLAERGHALPCIGYVYLLGKGVARIFHRN
QIPGCVVSDELLALVERQAAGPDRGKSFFIELAAKQAAILRGMGYRGAYLGGLSSPAQLD
AILERLGSFSPDDWRLFAKELQFPAPKEFYMYARHPETGLADAAARKPVPRAPAGALERL
AFAFNQVFHRLVFASTAPLFGPAARVYRALEKRPRLAASARDIENLIKAVLFGCRGCGDC
SLPETTYICPEFACPKRQRNGPCGGSFLGQCEAEDRDCIWVRAFRRCGGAEQFAALFQAA
PTFVDDALRTSSSWANAFLGRDHHRYEKGVKHGDSGTHADR
>A0A2T5GFC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hydrogenibacillus schlegelii|TrEMBL
MSDRNPSCAMPEVVVELDPPRAPAFDRYLQAARRLQAAGVTHITIADNSLAHARLSNVVA
AVLLRQAFGLSPIVHLNSRDRNLLAQQSTVLGLFAAGVRHFLLISGDALALGDHPDGKAV
YETDSLGLMERFRGLQAGVDFFGRPLEGPLDVCYGGALNLGRTLGPHLRRLAAKADRGAR
FFFTQPIFDPADLERLLEARALLGGRGTLYIGIMPLISAASARFLAGVPGMNVPSDVVRA
LEPYTGEAAIEAGLAQAEALIERAFELGWTRFYLITPYLRASTTARLARFVLARRPATGA
SPADDVSTGGGTSTRPGASVGVEAAPELGP
>A8XGR9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caenorhabditis briggsae|TrEMBL
MEEDVTLSILAGSLPICQVMSTKTDPPSESRSTRSRKFGTPFTKRGGKNSKEKNGMAILR
VNGIDSGDENAVVTEKPVFETSKSWSLKNYELLHERIERLIEEKTPFFSLEFFPPRFVNG
VPNFLERVERLSEGGSVFVDMTWHMGSDPANIDKVTSSSSIAASMLDYCGVDTMLHMTCV
QYNKADTLKHLEQAKAMGLRSILALRGDLPPGVCCGIVSNSFFIFMFQTELEDTNQFRAL
DMIRWIREEYGDYFSIGCAGYPLGHPQAPSYKADLQYLKAKCDAGANFVITQLFFEPETF
EKFVADCREIGITKPIIPGIMPIMGYESIKRIAKLSQLEIPEHILEDLEPIKHDDDAVQK
YGTERCIEMCRRLLDNGSAPSIHLYTMNREGSIREILKALGLWKLEGDRVFPWKNRSQHP
IRCLESVRPIYWSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSYYLSNLTTLRNGD
DRLSMFGENIESIEDVKRVFINYITQTPNVSGKKVTVLPWTEAETGVQPETSLISEQLVW
CNENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSEKLIDIIEREY
PVRVNYHAIDKDVSYILNSHDSMQIFRTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFR
AWRDEAYQMWMAQWGDFYPKESKSYGVIKSIHDTFRLVTLVDNDFQKPSVLFDVLQKALE
QLYQ
>A0A0D4BXE1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Psychromicrobium lacuslunae|TrEMBL
MSPPSILVDPLEKISAQHRAPVALSYELFPPRTPAAVDGLWTTIRELESTNPDYVSVTYG
ASGSNRDTAVELLHNLLSQTTLRPLAHLTCIGNTADELAGIITELLDAGVRGILALRGDH
PNDGTEEHPAGALNFAQDLVELIRRVEQRRSAMLAAGKVAIGVAAYPTTHPESPSQQHDI
EVLLAKQRSGADFAITQVFFHPEQYAELVLKARRAGVSIPIIPGVMPFTSLRRLQRLAEL
TGVQPDERLLAALASAGDDAERRRIGVSATTELAKAVLDVGAPGIHLYTFNQHQAALEVL
DRLDLVRPSAPTSKKRQLGAKTTLDSHSNLGSSH
>A0A2P4ETP6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halopseudomonas oceani|TrEMBL
MTTNAPISFEFFPTKTEAGHEKLLATAQTLAAASPEFFSVTYGAGGSTRDGTRRTVLQLD
GDVNVPTAPHLSCVGDSRDDLRALINDYRANGIKRIVALRGDLPSGMGHASGELRYANEL
VEFIRAETGDHFTIEVAAYPESHPQAPNFETDLQNFIRKARAGADSAITQYFFNADCYFH
FVDRVRQAGLDIPIIPGIMPITNYTKLARFSDACGAEIPRWIRKQLEAYGDDSDSISAFG
TEVISQLCERLLDGGAPGLHFYTLNQAEPCLAVLRNLHSGR
>A0A2I8QIV0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacteriaceae bacterium ENNIH2|TrEMBL
MSFFHANQREALNQSLAEVHGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRAIAKDYWDNGIRHIVALRGD
LPPGSGKPDMYAADLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVEAGANRA
ITQFFFDVESYLRFRDRCASTGIDVEIIPGILPVTNFKQAKKFADMTNVRIPAWMSQMFE
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAV
>M2SSI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O)|TrEMBL
MHISQKLAQAKREGKPTFSFEFFPPKTAQGVQNLYDRMDRMHSFGPQFIDLTWGAGGRHS
KLTCEMVKVAQSVYGLETCMHLTCTDMEKSKLDEALREAYQAGCTNILALRGDPPREREK
WEATAGGFRYAKDLVVYIKEKYGNHFDIGVAGYSEGSDDNDDVDELIDHLKEKVDAGGSF
IVTQMFYDTDLFLEWVRKVRAKGIDVPIIPGIMPIHTHAAFLRRAQWTKCHIPDDWTKAL
EPVKNDDVEVREVGKTLVADMCRRLIDAGITHLHFYTMNLAQATRMVLEELELLPDVESP
LEKPLPWRPSLALNRREENVRPIFWRNRQRSYVARTQDWDEFPNGRWGDSRSPAFGELDS
YGIGLKGTNEQNIKLWGTPLTIRDLSNLFVRYMEGKLESLPWSEQPITAEASSIRDDLID
LNRRGFLTINSQPAVNGVKSSDPVFGWGPRNGYVYQKSYLEVFVSPEHIAEIITRLDRDP
EFTYYAVNKNGDLKTNAPNEGPNAVTWGVFPGKEIVQPTIVETVSFLAWKDEFYRLGQQW
ANCHAGVSPSRYVIQDVIDTWYLLNIVHNDFHATRGIFPIFNDLEVKDMDKPLHTPSADL
PNVNGSETANGTNGVNGTNGTHKEESPSLIDVAKAAAIEVTNGMKSLAVSS
>A0A429D168|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis sp. WAC 01416|TrEMBL
MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAYMSITYGAGGSSRDGT
IRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNILALRGDPPGDVYGDWV
PHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADTEYLVRKLRAGADFAIAQ
LFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTPRTLHTSIKLSGAPAPRRLLDRLEPLA
DDPKAFRAEGIDAVTELCERLIAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A0Q6UZ79|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root122|TrEMBL
MRNKRHAATLARLLTAARYEVLPTASTEDKLLEHVPRDRTVTVTASPSKGLEATFDLAER
LHGHGYVVVPHLAARMVSGRSELEEIVDRLVGKGITRVFVPGGDAEPAGDYLDALGLLED
LAALGSPFAHVGITGYPESHPTIHDDLTVQSMWDKRRYATHIVSNLTFDPAVVRDWVRRL
RARGVTMPLLLGLPGPVERAKLLGMATKIGVGESTRFLAKNKGLFARLAAPGGFTGESFL
EKCAPALGEGALVEGLHVFTFNQIAETEAWRTDMLERLRS
>A0A127VUS1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sporosarcina psychrophila|TrEMBL
MNLLDTMKERILIGDGAMGTLLYSHGVDLCFEELNLTHPDQVLRIHQAYIEAGADIIQTN
TYGANYIKLARHGLEDSVKKINKAAVQIAKNAAGKNTFVLGTIGGIHGSRTSIGTKDEIK
RSFREQLYCLLLEGVDGLLLETYYDFDELTTVLKIAREETDIPIITNVSMHEAGVLQNGI
ELIDALQQLEDLGADIVGINCRLGPHHMLKSLETVPLMKRALLSVYPNASYPGYKDGKLF
YENEPEYFEKFALSFRKAGVSLIGGCCGTTPEHIRALVKGLTIREPIQEKLVKKKEVKTE
VVESELKESQPPTLLETVRKRHSIIVELDAPKHLNTGKFFEGAQALKDAGVDAITLADNS
LATPRICNASMASLVKQKIGATPLVHITCRDRNLIGLQSHLMGLHTLGITELLAITGDPT
KIGDFPGATSVFDVTSFELIQLIKQFNEGISKSGKSLQQKTSFTVAAAFNPNVRHLDRAV
ERLEKKIEAGADYFITQPIYSTEKIIEVYEATKHIETPIYIGIMPLTSSQNAEFLHNEVP
GIKLTDQVRARMALSDGNREQSTKEGLEVSKELIDVALEHFHGIYLITPFMRYDMTVNLT
EYIHGKVDVIVAREVVQTESIVY
>A0A1L3GQU5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Syntrophotalea acetylenivorans|TrEMBL
MAQNSRIKGRFLQRLEAGLIIGDGAMGTLLYNRGIPLGHSFEALNLSRPELVEAVHRDYA
AAGAQLLESNTFAANRLALGPLGLDGQVAEINAAGVRLARLAAGVDGLVAGAVGPLPSAK
GQAAELPLAEQRALFSEQMTALAEAGADLFVLETFAGIEELELALQVAEELGLPAVAQMA
FFEEGRTRHGLSAEEVARRLSAAGAAVIGANCGSGPRELLSVLQRMSTVTDRPLSGFANS
GLPQYVNGRYIYLATPEYFADMGREMVAAGACLVGGCCGTTPEHIQALAKSLEEVRPVER
SVPVIKVTEPSAVVEPVPTQRTFLDDWGHRPVVTVELGPPKGLDCRKVLQGAETLAKAGA
DAISLTENPLARIRMGNIALASQIQQQAGIEVIIHITGRDRNLIGLHSELMGAHLLGIRN
VLAITGDPVAVGGEAGASSVFDLNSVGILELLRSLNTGTTLLGADLGGTTRMLAGAAFNP
NVANMSGQIRRMEKKVAAGARFIETQPVYSPEVMLEMLERLAPLNIPVLVGLMPLVSERN
AEFLHNEVPGISLPDEVRQRMRGTSGSSGVEAGMAIARELIDAGRQTVGGFTLMPPFGKV
ELAVELLRYIRG
>C3GNZ8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus thuringiensis serovar pondicheriensis BGSC 4BA1|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNISDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVTEINRAAVKLAKASVTDRNAILGTIGGMKHIGAVTTTDMERE
FMLLEQASALLEEQVDGLLLETFYDEFELLHAVQVLRKETNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPKNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEAMTPKFIEQGIRLLGGCCGTTPEHIESMKRATLNVTPVIEKDTIQRPKVVH
THEKRSKAHVTLAEKAKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRISNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKAMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDIALIEEVYEATKHLEQPIFIGIMPLISKRNADFLHFEVPGIT
LPEAVRERMDGHETKEAAIEEGIRISQELIDETMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A2P8HSG9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Chitinophaga niastensis|TrEMBL
MSYFCPRNFSGNKGLHQPAPFHKAYNFMKVTEHIARAKDTLISFEILPPLKGKSIESIYD
HLDPLMEFKPSFINVTYHRSEHMFKKKADGAFEKVEIRKRPGTVGICAAIMNHYNIDAVP
HLICGGFSREETENALIDLNFLGIDNVLVLRGDAPKNETFFEPDPHGHSYAIELLDQVVH
MNNGVYLEDDLQSGVKTSFCIGVAGYPEKHFEAPNMQTDISHLKRKVENGADYIVTQMFF
DNQKFFDFVNKCREMGITVPIIPGLKPLTSKKQMTILPRIFHVDIPSDLSSEIVKCKTDK
DVELVGTEWLIAQSKELKAFGVPVLHYYTLGKPKVVRQAVEAIM
>A0A263DA90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Amycolatopsis antarctica|TrEMBL
MTTVVERLRGDGPKFSVEFFPPRDAEDETVLWRSIRELEQIDPAYMSITYGAGGSSRDGT
IRNIARAATETTLVPMAHLTAVDHSVAELRNVIGWYASVGVRNILALRGDPPGDVYGEWV
PHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSPDLDTDTRHLVRKFRAGADFGIAQ
LFFDAEDFLRLRDRVAAAGCEAMLIPGVMPLTTPRTLRTTVKLSGAPAPSALLDRLEPLA
GDPAAFRAEGLDVVTALCERLLAEGVPDLHFYTFNRSKATREVVSRLGLVPARA
>A0A3N1I2Q6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Enterobacter sp. BIGb0383|TrEMBL
MSFFHANQREALNQNLADLHGQINVSFEFFPPRTSEMEQTLWHSIDRLSILKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAVPHLTCIDATRDELRAIAQDYWNNGIRHIVALRGD
LPPGSGKPDMYATDLVCLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVTAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSQMFN
GLDDDAETRKLVGASIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPAI
>A0A0Q8WJ52|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides sp. Root240|TrEMBL
MDITTRLRSGQGDVVLFAITPPRRSTPAERLPEIARATIERLQHLDLDGLILYDIDDESS
RNPVERPFPFSPTVDPSDYRAAHLPAWPTPVVVYRAVGKYPREGLQDWIREQDADRTLTV
MVGAASSGTSAPVTLSEAQAMRADLNPDLLLGGVAIPERHSRRDNEHLRLIAKQEAGCRF
FVTQVVYDLNAAKNLVSDYRYACEERGLEPVPIVFTFSVCGSMKTLEFLRWLGVDVPRWI
ENDLRHAKNPLAASLDQAVATAVELVDFCRRLGVPFGVNVESVSIRREEIEASVELASQL
IGHLRADAATP
>A0A560Q132|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas sp. SJZ079|TrEMBL
MSQERRYSFEFFPAKTEAGHEKLLNTARQLATYKPDFFSCTYGAGGSTRDRTLNTVLQLD
GEVKIPTAPHLSCVGDSKAELRELLGLYKSAGIQRIVALRGDLPSGMGMASGELRYANEL
VSFIREETGDHFHIEIAAYPEMHPQARNFEADLANFVRKAKAGANSAMTQYFFNADSYFY
FVERVRKMGVDIPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDAESIRAYG
EQVISEMCERLLQGGAPGLHFYTLNQAEPSLAIWNNLKLPR
>A0A496U8C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Fermentibacteria bacterium|TrEMBL
MEKPVLSLEVFPPKPGYSLKTVFRTLDGLRDLNPSFVSVTYASRGDSTEKTVEIASRVRD
EYGCESLAHMTCIGHTRSEVKTVLDSLETRGVRNILALRGDIPPDSSAENRDYRYASELI
NEISARESFCVGAATYPEGHMEAKRISHDLDNLRRKVDAGAEFLISQLFFDNRVFYDFLE
RVRGRKIDVPVVPGIMPILNYKQIKRIVMMCGVSIPAKLLNLFDRYSHNPDDLAKAGVDY
AIAQISDLVKEGADGIHLYTMNRIPQIREIVFRSGQREAK
>A0A4W3H8K7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Callorhinchus milii|TrEMBL
MMVKQRQHNGQLSKSGESCSDSSSRESSRSSTPSLESDRLREKMRRRIESGDKWFSLEFF
PPRTASGAVNLLSRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETL
LHITCCNQSKEQITEHLQKACRLGLKNVLALRGDPIADKWQTEEGGFNYASDLVKHIRNK
FDDYFDICVAGYPTGHPECTSYEEDLKHLKEKVEAGSDFIITQLFFKPQTFLKFLKDCRA
IGITCPILPGIFPIQGYHSLRQLVKLSKLQVPQEIKDIIEPIKDNDAAIRNCGIDLATDL
CKALLTSGAVPGLHFYTLNREVAATEILRRLGLWIEDPRRPLPWAVSANPKRKVEDVRPI
FWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELNDYYLFYLKSNCAKEELLKMWGEEL
VNEEHVFEVFTAYITGESNRNGTKVTCLPWNDESLAVETNLMKAELQKVNRRGILTINSQ
PNINAKSSTDPVVGWGPEGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYHIVNVKS
ENINNASDLQPNAVTWGIFPGREIIQPTVVDPISFMYWKVIPVLLLRLIFQIIPQTCLLP
HRHNR
>A0A2T9YJP8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Smittium megazygosporum|TrEMBL
VAKEKGIRNILVLRGDEPLTQTDALDDTPKDVGGSRFQYASELVRYIRSKDAYKNFFNIG
VAGHPEGYINSNFPTDKEQDHSSISTSCGQGSNIGKEKVSETHKKFDKELREIMCLKDKV
NEGADFILSQIFYNTENFIKWYIKCKSIGINVPIIPTLLPIQTYSSFQRIVKLTGIQVPE
KLQERLSLVKHDDKLVKSIGVEYCIEQVNTISSMLGVANFHFATLNLEMSVSKVLTKSGL
LDLTDKENLNDNSDSVANILLGQGFGVASSSSQDGIDKRKAQILWDEYPNSRWGDARSPS
FFNETLYGQYGSMVSELGSWGVPKTEADINELFRGYVNKQKLSLPWTNDSIEVFDTKHKA
VLEKMCLNGLWVLASQYGIDGVSSSDKEYGWGPENGYVYQRSFVEFFVRKPLLLKLAKFL
NIHKKEISFYAATFGDRSSQQNGDAFAGVSGDGNALGTGEQEDQKVHIITSRSKGKELSD
ELFQEDLLPSEISQVVIESKEEKALNIAGGDEACGYAASENSNENEEIESTVLTWGVFPH
KIVQAALIDRLNFGFWSKEAIQVWHVWSKLMEYRNRTSSGFLGQVADDVWLVNVIGNDYK
HPYELFELLEKFTL
>A0A1S2K035|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. CC53|TrEMBL
MALGTPSTRTDRARTVRDLLASGTTYSFEFWAPKNEKGERNLWNALRRVEAVAPSFVSVT
YGAGGSTREGTVKATQDIAADTTLTPVAHLTAVGHSVAELRNMIGQFADAGIRNMLALRG
DPPGDPMGPWVPHPEGLHYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWDTDVRHFVDK
CRAGADYAITQMFFDPEHYLRLRDRVAAAGCDTPVIPEVMPVTAVRQLDRLPQLSNAQFP
AAVKERILAVKDDAAAVRSVGLEFATEFCARLLSEGVPGLHFITLNNSTATLEIYENLGL
HPQS
>A0A2P2GZG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus flavus (strain ATCC MYA-384 / AF70)|TrEMBL
MGMFPFPLIGGPVKLRPKPFPPRWISPQSSLFNYHLSRNFAGTDSGIKMEKITDKIAALP
PDANYFSLEFFPPKTQMGFANLQARLERMAQALRPLFVTVTWGAGGSTAQRSLELAEICQ
RQLQLTTCLHLTCTNMSRALVDEALEEAKVLGIRNILALRGDPPRSEEYNMHGEDDSNRD
FTFAVDLVRYIRQKHGDYFCLGVAAYPEGHPVDSFQDVQDPKTDLPYLVEKTQAGADFIM
TQLTYDIEAYTRFENMLRNHESGAFKTIPIIPGLMPIHSYKILTRVTKLSHVQIPPQILS
KLEEVKHDDDSVKRIGVDIISSLVDGMRDIPCPGLRGFHFYTLNLEKTVSFILERCDLIP
PYSEDFDAIEEGGDISAMDGAHLRSLTRRRASSINSLPHNRVIVDKLHASEVSSKASVSH
EAPATSAGMPAMPPDRSTTLQISEGLGALGREATWDDFPNGRWGDARSPAFGEIDGYGPS
LHVPPAVAHRIWGFPVSHEDISALFHRHVSGELHMVPWSEGGAEEGSSGLNAETEVIRPE
LLQLIDGNGWWTLASQPAVNGVRSDDPIYGWGPPREGFVFQKPFVEFFCPSKDYHSILKP
LLQKHGHEELAWFAANVKGDFESSLPAQTSDADPIEMNPNNVNCVTWGVFRGKEIVTPTI
IEEVSFRAWGDEAFRIWDEWRRIYPRNSATERFLNDIKDDVWLVCVVGQDFGAGTEMGSE
EEEDEKKFMWRVLLNAKK
>A0A239J3U8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micrococcales bacterium KH10|TrEMBL
MTSEDYACPPGTTLRPTISFEVMPPRNPSAAPRFWNTVEQLVTVQPDFMSVTYGAAGTDR
ATAREVVARLLRSTPVLPIAHLTCVGHSRADVVAVVDEFLSAGVRSFLALRGDPPAGQPE
WQPTPGGVNSSVELIALLRDRERQRCASHPGNALRGAAQPLTIAVATFPAGNPAAGTTPE
QEIERLLVKQAAGASFAITQLFYEPATYADFVTRARYAGVQIPILAGILPATDPARLNRV
AELLGVQAPQDLLDSLTAAGSDEDQYERGIAATIQLARDVLDAGAPGLHIYTFNKAKPAL
DILTGLDLIPHVQPPHQHDTLTAPAVAKGIPA
>A0A6B3BJG0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID9727|TrEMBL
MDLVTDRPTFSFEFFPPRTAQGERTLWQAIRRLEPLGPDFVSVTYGAGGSSRDRTIDVTK
RLVTETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLVLRGDPPGDPKGEWTAHPDG
FHHAYQLVELVRSLGDFTIGVAAFPERHPRSPDWDSDIRHFVAKCRAGADYAITQMFFDV
EDYLRLRDRVAAAGCTTPIIPEIMPATDVRQIRRFAELSDAAFPEDLAHRLEAAQHRPDI
AYEIGVAHATLMADRLLAEGAPGLHYITLNKSTATLDIHRNVMSTRSLHAS
>A0A7W2G1U5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Clostridium sp. cel8|TrEMBL
MSIKSILNEKKFILSFEVIPPRNKESVPAFENKIQHLNKMSPDFISVTYGAAGRSKKGSL
KAALYIKKKYGIEVLSHLTCINSTESEIEQYVNSLIDGGVNNVLALRGDIARGINKNQNL
KYKYAKDLVKYLSKRQDICIAAATYPEGHSESESFEKDILYLKQKVECGVDFLITQFFFD
NGYFYRFREKIEKLGINIPIIIGIMPVTKVRQLKNMSSLGGASLPNELIKIIDKYGDNEE
DFFKAGLEYSLNQTRDLAKNAVDGVHIYTMNNLTAVDYIVNNL
>A0A6L5C7H7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ephemera danica|TrEMBL
MSMNSFHARQKKPRPAPLPAHERPAGMLRADALLVALKFAPSRTVAQRMIKAGQVRWSGG
MIARPAQELPAGTVLTVAAEADARFVSRGGQKLAGALAQTRLDVGGKDCLDVGQSTGGFT
DCLLQNGARHVVGVDVGHGQLHSQLRCDPAVTAIEGINCRSLGVADLGESFPPDGFDLIV
ADLSFISLTLVLPQLPPLLAANGHLLLLVKPQFEVGPGNVGKGGIVRNAALYGAVETKLR
QCAAHLGLSVKSWLDSPIQGGLDKLRATRARLAELKPAFFSVTYGAGGSTRERTFSIIKE
IAAEGFDAAPHLSCIGSTRERIREILGEYKAAGIRRTVALRGDLPSGMAEAGEFRHANEL
VDFIRAETGDWFHIEVAAYPEWHPQARTPKDDLDAFVRKIKAGANSAITQYFYNPDAYFH
FVDEVRAHSVDVPIIPGIMPIAGFTKLARFSDACGAEIPRWMRRKFESYGDDVDAIRAFG
LDIVTELCQRLLRGGAPGLHFYSMNQSALTLEICRRLGGSTL
>A0A2H5Y0L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bacterium HR21|TrEMBL
MDSIEVERRAVPAAQRMKEAFPQRLQQGIVVMGGSIEAELQRRGLHEQPPELYNLRQPAV
VEEIHRGFVEAGVEVVLTNTVRANRIALERYGLADKVYELNRTGVWLARCAALHRAYTAG
VVGPTGRFLAPLGNVTAQQARQAFIEQIVALVDGGAELLVLKGFIELEELQLAVEAAQLV
NPRLPVIALKAFPEDGAVLASSFPARVARAVSRLPIVALGAAGTVGPQRMVGIARALVSA
TEKPVCALPDVSVPRIIGDVRFYDPEPDYVARMAQELVSLGVRIVGIDGGATRECVQALV
AAVRQVPHGAVSVSTPESSADPPVPEPLVPEPTPFAQKLGRKFLITVELDVPRGFDMRSV
LEGARFLRRWGVDAVNISDGARARLRMSPIALSHLVQSQTGMECITHLACRDRNIVALQA
ELLGAHALGVRNILAVTGDPPHIGDYPYAKAVFDVDSIGLIRILRLLNEGRDAMGNPLGA
AAGFCIACSCNPVAEQWETELERLERKVAEGAHVVFTQPVFDPELWERFRQATAQLPVAV
LVGVLPLRSLRHAEFLHHEVPGIVIPRWVRQRMARASNPEDALREGIAIAVEFIRAVQQS
ADGVYLMPPFRRYDVAVEILRQLELVPEQPQVAP
>A0A836G5W7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leishmania enriettii|TrEMBL
MSGLILDAIAAEDVGKWYTSYEFYPPRSEKAEEEFMKVLIPKFIRQSPVFLDLTWGAGGR
TSETTMRLCKDLQHAYPDTPINMHITCTNMPRGLVKETLDFAKAHGIRNILALRGDPPHG
EEYQANPDGFACAKDLVRYIHATYGDYFCVSVAGYPEGHPSRIAEDGTISDEDSQKELDY
LKEKVDAGASVVITQIFYDASLYVKFVKRCRERGIMVPILAGLLPITTYAGFKRMVSLCK
TSVPSDVRKRVEELKDNSEGLKEYGVEQCVQMIEHIRSSGLDYHHLHFYTLNSSAQTFKI
LKRLDALVE
>A0A674KFX3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Terrapene carolina triunguis|TrEMBL
MVNEPHSASNGSASSRSDGSSSGSEGSKDSSRCSTPVLDAERHERLREKMRRRYDSGDKW
FSLEFFPPRTANGAVNLISRFDRMGMGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVNY
CGLETVLHMTCCNQTKEEITGHLQKAKHLGLKNIMALRGDPIGEEWEEEVEGFNYAVDLV
KHIRCEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVSAGADFIITQLFFRSKTFLAF
MKDCQAIGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKEVIEPIKDNDAAIRNYGV
ELAVSMCRELLDSGMVSGLHFYTLNREVATTEILKRLGIWKEDPRRPLPWAVSAHPKRRV
EDVRPIFWASRPKSYIHRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLK
MWGEELMSEESVFEVFTCYISGEPNKEGHKVTCLPWNDDPLAAETNLLKEQLEKVNRRGI
LTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSENITALLKVLKTKKYELRVN
YHIVNVRGENITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAK
LYEEESPSRMIIQYIHDNYYLVNLVDNEFPLENCLWQVMEDTFELLNCPTEQ
>A0A838R408|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pirellulales bacterium|TrEMBL
MKIEEPSSIDVSFEFFPPKPGEAEQSFWRTIAKLKAVRPQFVSVTYGAGGTTRDRTLETL
ARIRRDTGLNPAGHLTCVNASKAEVDAVIHAYWAAGVRHIVALRGDPQGGAGARFVPHPG
GYRNAADLVRGIRDIGGFEISVAAYPERHPESVSIEEDLAFMADKADHGATRAISQFFFH
NAFFLRLRDRIFARGIGIELVPGILPITSFAKVSEFAAKCGAHIAPALARRFEGLDNDPE
TLNLVAAMVAAEQVAALRREGVRHFHFYTLNRADLVYAICRLLDLGTANEKAA
>A0A0N7LPN3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ruegeria atlantica|TrEMBL
MTKPEISFEFFPPKTLEASFRLWDTVQTLAPLEPRFVSVTYGAGGTTRELTRDAVATLHK
SSGLPVAAHLTCVDASRQETLEIADTFARAGVQDIVALRGDPPSGQDRFEPHPEGFANSV
ELISALAETEMFNIRVGAYPDIHPEAQNARTDIDWLKAKLDAGADEALTQFFFEAETFFR
FRDACEKAGIDKPIVPGILPIENWKGARNFAKRCGTRIPQWVEQAFEKAVRDDREDLLAT
ALCTELCSDLIGGGVDKLHFYTLNRPELTRDVCFALGITPKADLQNVA
>A0A1F3T5F3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionales bacterium GWB1_55_8|TrEMBL
MAVFPFKPDRKLTDVLRESPFTLSAEVIPPRNGSEQAKVLDQIQLLTQAGAQFLAVTKGA
GGSLRGGSLPIAQAIKETFGVPCIAHFTCRDLTPFEVENQLVDHHYFGIRNILALRGDPP
EGVIEWKPREGGYNYAYELIGQISSMNRGDYIPRPGGPGRDGFERTDFCIGAALYPDFPD
SEKRISYFEKKVLAGAQYGITDMLFDPDVYARFRDQCDRNGITVPILPGTRILKSRSQAL
KMAARFNVTIPASLLSQLPEEPGPDSEERGIEVLLKLVSRLRELGAPGIHLFVISDAQAA
VGALKLLAPLLG
>A0A4Y9FNI9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus acidominimus|TrEMBL
MVHTPSLSFEIFPPNPSAGNEKILSALRDMQDLAPHFISVTASNNKFNIEETTVRLADYI
HNDLGIPSIAHLPAIYLTKAQVSNILTALDQIGVHTILALRGDRIPNVAPKNDFRYATDL
ISFIKEEAPHFDIIGACYPECHPDSPNSISDIKHLKKKVDAGCSSLVTQLFFDNDVFYDF
QEKCQLADIDVPIVAGIMPIINRNQALRLLHTCENIRLPRKFRAILDKYEHDPESLRAAG
LAYAVDQIVDLVTQDVAGIHLYTMNNPQVANYIHHATYSLFKHSAV
>A0A5B2TJM5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseomonas oryzae|TrEMBL
MNQIADHAAAPAAASEGTLQRWLTAPRVAGLPTEMAPPALSFEFFPPRTEALEQQLWTCV
RRLEPLAPRFVSVTYGAGGTTQERTHATVARLVRETSLTPAAHLTCVGASRGEVDDVARA
YWDAGVRHIVALRGDAPAGEASYTPHPEGYAYAADLVAGLKRVADFEVSVAAYPETHPTA
QSSAHDIDNLKRKIDAGATRAITQYFFDTEVFLRFLDRALAAGITVPIVPGILPVSNFKQ
VAKFSAMCGAGVPAWMGKLFEGLDDDPETRRMVAASLAAEQVRLLRANGVDEFHFYTLNR
ADLTYAIAHILGARPRQLALA
>F9PTZ3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus infantis SK970|TrEMBL
MSRQTPSLSFEVFPPNPSVGNDKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPGVEPQKDFRYATD
LIEFINEQAPHFDIIGACYPEGHPDSPNQISDIQNLKRKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQP
>A0A502KVS0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Litorilituus lipolyticus|TrEMBL
MSYSHARQVESLNRSLSEISNDIQVSFEFFPPNSPEMETTLWNSVERLAPLKPSFVSVTY
GAGSGTRDRTHDIIKRIQKDTALLAAPHLTCIDAGRDELVQIAKDYWDSGVRHIVALRGD
LPNSNEKPNMYASDLVELLRDVADFDISVAAYPEGHPEAPNPQFDLLNLKRKIDAGANRA
ISQFFFDIESYLRFRDRCVTVGIDVEIVPGILPVTNYKTLERFAGLTNVHVPSWMTKMYE
GLDDDEMTRRMVGANIAMEQVKVLNREGVKNFHFYTLNRAELTYALCHTLGIRPEK
>A0A3S4ABQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces albidoflavus|TrEMBL
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSV
TYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVD
KCRAGADYAITQMFFDPEDYLRLRDRVAAAGCATPIIPEIMPVTSLRQIERFAQLSNAVF
PRKLEERMRAAADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLG
LHDDKG
>A0A3N5DBW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aurantiacibacter spongiae|TrEMBL
MTQPDPGTRLADAPSRFAGLPGDIAVSFEFFPPKGDKGDEQLQRTVERLAPYEPDFVSVT
YGAGGSTRAGTITALERIVGSTSVPVAGHLTCVGASKVEVNEVAERYRAMGVTHIVALRG
DASPPGTPYSPHAQGYRGAAELVEALARTGHFDISVAAYPEAHPESPSVEDDIANLRRKV
DAGANRALTQFFFEPETFLRFRDRAVAAGIDVPIIPGVLPITNFKQTCKFAGICGATIPD
WMANAFDGLDDEPAIRNLVAATLAAEFCGKLYEEGVRDFHFYTLNRADLSYAICHLLGLR
EKAREPVAA
>M7SBI3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eutypa lata (strain UCR-EL1)|TrEMBL
MEKITDKIAALPADSNYFSLEFFPPKTVMGFANLRDRLDRMARALRPLFVNVTWGAGGST
ATKSLELAEICQRELNLTTCLHLTCTNMSRKLIDKALEDAKVLGIRNILALRGDPPRADE
YQGPNEDPENAIDEGFVWAIDLVKYIKKNHGDYFCIGVAAYPEGHAEESHPQGQSLEHDL
PYLVDKTLAGADFLMTQLFFDTEAYEKFEQTLREHPSGAFKTIPIIPGLMPIQSYQMIKR
TTKLSHASIPGPISARLDAVKQDDEKVKNVGVDIVSEIVEQVKKIKSRTPGPRGFHFYTL
NLEKAVSFILERTSLIPPSTPEVEEAVVDDLAVNVPKLEINGSPQSTPAPTQDRERRQST
VGSEPRNRVIVSERSLSHPEYEATPAEASMLAGPLNTRANTLAISEGEGALGREATWDDF
PNGRWGDARSPAYGEIDGYGPSLHVTNAQAVALWGHPETVGDVNALFVRHLRGEVSAIPW
SEEEFNPETATIAAELVSLNSKGWWTVASQPAVNGLPSTDPTYGWGPRQGFVFQKAFVEF
FLPAADWRVLEQKLRGPGVRENVCWYAANAAGDFMSSDALSAAAAATAAGSEGQQEEEEA
AADVKDKEQQQPSTNAVTWGVFPGKEIVTPTIIEEVSFRAWSEEAFGIFAEWAKVYDKGS
ASARLLEGARADAWLVNIIHHDYVDKDALWNLLLK
>A0A1D2RW42|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arenimonas sp. SCN 70-307|TrEMBL
MTAISLEFYPPKNDEQRAQLDRTVRRLAPRAPQFVSVTFGAGGSTLSYTPETVRSLRQDH
GLDAAPHLSCMGGTRAELRELLQLYRALGCRRIVALRGDLPSGMARMGEFRYASDLVAFI
REEHGDHFRIEVGCYPETHPQAEDALADLRHFKAKVDAGADSAITQYFFNADAYFRFVDD
VRAAGVGIPVIPGIMPISNFSQLRRFSEACGAEIPRWMAKRMQAYGDDAESIREFAADAV
AAMCRRLLEGGAPELHFYTLNLAKPTEAVLSRLG
>A0A7X7UNG1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MHIANILANTQRTLFSFEILPPLKGGSFEDLYKSIEPLMEFNPPYINVTYHQEEVVYKDK
GNGLLEKKVVRKRPGTVGISAALQYRCKVPVVPHIICGGFNKEETENALIDLNFLGIHNV
LAVRGDPERSQKVFIPEPDGHAHTLDLVKQIIAMNQGRYLDDELRNSTPTNFCVGVAGYP
EKHPEAPNFDSDIRYLKMKVEAGASYIVTQMFFNNKHYFDFVERCRQQGINVPIVPGLKP
IALKQHLSILPRTFGIDLPDELVREIEKCNNNQQVRQVGIEWAVKQTKELIAAKAPAVHF
YTMGRSDNVYQIARQCF
>A0A6I1MYX7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Duganella sp. FT27W|TrEMBL
MANHNFSIEFFPPKTAEGADKLRATRAKLSELKPKYFSVTFGAGGSTQRGTLDTVVEILA
AGEDAAPHLSCVGGSRESIRAILAEFKSHNIRRIVALRGDLPSGYGGAGEFRYANELVEF
IRQETGDWFRIEVAAYPEVHPQAKSPQDDLLAFERKIKAGANAAITQYFYNADAYFQFVE
QTRKLGIDVPIVPGIMPILNYTQLMRFSDMCGAEIPRWVRLKLASFGDDSASIKAFGLDV
VTQLGERLLAGGAPGLHFYSMNQAAPTTALWQRLV
>A0A7C6G457|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKISELIDNTQQTAFSFELLPPLKGNSIAQVFRTIDRLKEFDPKFINITTHHSENIYRED
ENGVYRKTNVRKRPGSVAIAAAIQHRYGIRAVPHIISKGFSKEETEYALIDLSFLGVTDL
LLLRGDSKKLDAQQRSMDSHDHATGLQEQVNNFNRGIAFDGTSFTPPETPFSYGMACYPE
KHEESPNMESEIYYTRMKADNGADYLVTQMFFDNSKYFAFVERCRAAGITIPIIPGIKPV
HLLSQLTVLPQIFRSEIPESLEKELRKCKNDEEAKEVGVEWCIAQCRELVAHRVPSIHFY
SLMATESVRRVAKEIY
>A0A7X8HBJ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MAFGLKPARRWQPAFYPFRRESFGRRLLAGIEIMIKGPLFGCRMCGNCLLQETAFICPME
CPKGMRNGPCGSVTPDKRCYVDESRKCIWNAIYERAVRTGREKTLLEVLPPVDWSKAGTE
TWAGVVSQVRKTGTGRFLGSFFLKDTTKKQEIWDSVFKTIRQPEWWMGDPEYHPPSYSDP
ASELERRLKNGRFVVATEVTPPVGADSQKLRRDIELVKPYVTAINFTDAASGIPRMSASA
CCKVAAELDAEAVFQIAARDTTRTGLQSVVIGAGQLGIRNILCVSGDSSMAGPLPTSNMN
ILDLDSVQMLWILRRMRDEGIYLDGRKIKSPPKFFLGAATTPFAMKPELQAIKDQKKVNA
GAQFFQTNIVFEPERLDPWLEQLEKRGVLENVYILIGMVPLRSYKAALHLHQKVPGVYLP
PKILERMENAGDRAEEEGIQITLETIESIRHKKGINGIHLMTLGWETVVGRIIKESGLDP
QSVF
>A0A1X0NM13|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Trypanosoma theileri|TrEMBL
MLVPSLSDLLSNEVDDNIYSSLEFLPPRTEKGEEKLWNEHLPHFMKTNPLFVDITWGAGG
RTSDKTMRLSKQIQEKYGIPVNMHITCTNMPTGLLKETLNFCYENGIRNILALRGDPPEG
EEWKPNEEGFTCALDLVKFIRNTYGDYFCITVAGYPEGHPSRIHGEDGKITDEEMEKELN
YLKAKVDAGANVIITQLFYDAEIFIVFVKKCRNYGITVPILPGILPISSYRSLTRMINLC
KTYVPPSVLEQVVKLSEDDEALRTYGVSQAEEMVHAIQAADIGIKHFHFYVVNAPDVTKR
ILDALNFTP
>A0A380G4F2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Staphylococcus intermedius NCTC 11048|TrEMBL
MSRLLNALKNNILVADGAMGTILYSEGLDTCPEAYNLTHPDKVESIHRSYIQAGADVIQT
NTYGANFEKLQQFGLEHQVKAIHQAAVAIAKRAAGPNTLILGTVGGFRSVKQGELSLSAI
QYHTDIQVDTLVAEGVDGLLFETYYDEEELLNAIRQTRQKYDIPIIAQLTASNTHYLMNG
KEINSALQQLVEAGADIVGLNCHHGPHHMKQTFGHIELPNNAYLSCYPNASLLDIDQQTF
KYSDNAQYFGETAEQLIQEGVRLIGGCCGTTPEHIRKIKAAVQDLKPIKEKKVIPIHQKQ
TSEAPKETRQNLAARVRERPTIIVELDTPKHLDTTKFFQNVKALDDAQIDAVTLADNSLA
TVRVSNIAAASLIKQQFDIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSKV
GHLPGATNVYDVNSKGLTELALRFNKGVNTDGDTLKVATQFNIAGGFDPHVSNIKAAVRK
METKIKSGMHYFITQPVFTKEKIVEIYEATKHLDVPIFIGIMPITSYKNALFLHHEVPGI
KMSDDVLAQFEAVADDRQATYELSLSLCKSLIDTVHTYFNGLYLITPFERIDYSLELATY
SKSITTSHQEAIL
>A0A2U3WPW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Odobenus rosmarus divergens|TrEMBL
MDHPTPKVLPARPRGPSLGMWALETGRVRFSVPPSISRNPAMVNEPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERRDRLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQEQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYLS
GEPNQHGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPTPEQGAEAL
>A0A6C0G621|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus lycopersici|TrEMBL
MQLSDKIRNRQTGIITYGMTPPKASYPPEQIAEIARKQCERLEGLPIDGLILYDVQEESD
RIEQDRPFPYLRTVEPTRYSSEYLSRLKLPKIIYRCVGKYSGTELAEWLQAEPEQERFSV
FVGASSGKQEVTMSLPAAYELSRTANPKLTFGGVVIPERHQTKGDEHLRIAAKIRGGCRF
FISQAAYNVEAAKDFLSDYYYYCQQHDIDMVPILINLAPCGSEKTLDFMKWLGISMPKWL
ENDLKHSNDVLDKSIRLSQKIFEEIFEFGLEKGIPLGCSVESVSTRKVEIEASIQLVRDI
KATIERRLR
>A0A2T0GUM7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinopolyspora mortivallis|TrEMBL
MTRVVDRLQPGRTVFSVEFFPPRSDAEEQILWKAVRELEPLNPAYVSVTYGAGGSSRDRT
IRTVGRIARETTMLPMAHLTGVDHSKDELRHVVGSLADEGIRNILAIRGDPPGDPMGEWI
PHPHGILYADELVRLVRSCGDFSVGVAAFPHMHPRSTDVETETDHLVNKIRAGADFAVAQ
LFLQPEYFLRLRDRLAARNCHVPLIPGVMPITTPKVLSKFEHLAGVPVPSEVSAALDPLA
EKPEAFRAAGIELITRLCERLISEGVPGLHFYSLNRAKATREVVDNLGLAEGVPQPV
>A0A8C9K843|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Panthera tigris altaica|TrEMBL
MDHPTPKVLLARPHCPSLRMWALEANSGRFSVPPSISRNPAMVNEPRGDGGPTSRSEGSS
SGSESSKDSSRCSTPGLDPERHDRLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCCQSREQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDVCVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPREELLKMWGEELTGEESVFEVFACYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPIVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
>F5X1K8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus gallolyticus (strain ATCC 43143 / F-1867)|TrEMBL
MSRLLERLKTDILVADGAMGTLLYANGLDNCYEAYNLTHPDKISAIHHAYLEAGADIIQT
NTYAAKRHRLKGYAYDDQVKEINQAGVRIAREAAGDDAFVLGTVGALRGLKQCDLTLDEI
IEETLEQVGYLIETNQIDGLLFETYYDEEEIIEVLKAVRPITDLPIITNIALHEAGITEN
GRPLVEILGKLVMLGADVVGLNCHLGPYHMIKSLKQVPLFAQSYLSVYPNASLLSFVDDN
GSGQYGFSQNADYFGKSAELLVAEGARLIGGCCGTTPDHIRAVKRAVKGLKPVERKFVTP
MVEEAELIKAAKQSETLVDRVKREVTIIAELDPPKTLDIAKFTEGVKALDKAGISAITLA
DNSLAKTRICNVSIAALLKNEISTPFLLHLSCRDHNMIGLQSRLLGMDVLGFNHVLAITG
DPSKIGDFPGATSVYDATSFKLLALIKQLNKGQGYSGASIKKETNFTAAAAFNPNVKNLS
RCGRLIERKVAAGADYFITQPVFNTEIIDELADLTRDYEAPFFVGIMPITSYNNAIFLHN
EVPGIQLSDEFLAKLEAVKDDKETCQKLALEESKQLIDRALEHFNGIYLITPFMRYDLTV
ELIDYIHQKVELKNQRIS
>A0A7X6VWM1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVIDIIKNAKKTVFSFELLPPLKGSDASRIYNTIESLLEFDPKYINITTHRDETEFREL
SNGSIVKRTIRKRPGTVAIAASIQHRYNIPVVPHILCGGFTKSETEHVLIDLNFLGIENI
LALRGDGIRGQQFFQPEKNGHSNANELVSQIINLKKGVYLEEDLKNNAPLDFCIGVAGYP
EKHFEAANTEQDLFYLKQKVDAGADYIVTQMFFDNRVYYEFVDKCRKGGITVPIIPGIKP
IHMKNQLTTLPRLFHVNLPKVLTDELTKCKSNEDATQVGTEWAIYQSKDLIANNAPSLHI
YTYGISDNV
>A0A6B8T6C7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Capnocytophaga sp. FDAARGOS_737|TrEMBL
MKITDHIKNAKGKTLFSFEVVPPKKGNNIEELYRNIDPLMEFNPPFIDVTTSREEYYYIE
HPNGLLEKKVTRMRPGTVGICAAIQHKYKVDTVPHVLCGGFSKEETEYLLVDCLYLGIDN
VMALRGDAMKEQRYFQPTEGGHTYATELVTQISNLNKGIYLNGIAADHKANFCIGVAGYP
EKHIEAPSLTSDLARLKEKIEAGADYVVTQMFFDNQKYFEFVDKAREAGINVPIIPGIKP
IAVKKHLNLLSQAFKIDFPQELVEAVEACKHNADVKQIGIEWAIQQSKELKAAGVPVLHY
YSMGKSDNIVKVISEVF
>A0A3D4TZ70|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MKVIEHINNAKSTLFSFELLPPLKGSTLQTIFDTIDPLMGFNPAYINVTYHREEVVYRPG
ANGSLIPTVLRRRPGTVGITAAIQHKYKVDVVPHIICGGFTQQETEDALIDLDFLGIHNI
LVVRGDADKIVGKFEAKAGGHRYAVQLVKQAIAMNKGAYLDECLEKPNPTNFCVGVAGYP
EKHAEAPNVTSDLQRLKEKVDAGADYIVTQMFFDNSKFFEFEKHCREIGITVPIIPGIKP
ISLKEHLSILPRIFNVHLPQELVTDLEKCADNKAAKELGVEWAVAQAKELKEKGVPSIHF
YTMGKSDNIVKIARRVY
>S3ZQ97|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces aurantiacus JA 4570|TrEMBL
MLATGKTTYSFEFSAPKTPKGERILWNSLRRVEAVAPSFVSVTYGAGGSTRAGTVRETQQ
IVADSTLTPVAHLTAVDHSVAELRNIIGQYADAGIRNMLALRGDPPGDPMGEWVKHPEGL
TYAAELVRLIKESGDFCVGVAAFPAMHPRSADWESDVRNFVDKCRAGADYAITQMFFHPE
EYLRLRDRVEAAGCETPIIPEIMPVTNVRQLERLPQLSNADFPPELKERILSVKDDPAAV
RSIGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIYENLGLHHQQV
>A0A2J8GE23|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Arthrobacter sp. AFG20|TrEMBL
MSPPSLIETHPNLSDTAPVALSYELFPPRSPAAAETLWNTIRELEATDPDYVSVTYGASG
SNRDTAVELINRLVLETTLRPLAHLTCVGNTPTELAEIIGELLDAGVRGILALRGDLPKD
SGEPVSGSLRYAQDLIELIRRVEQRRSALLCAGKVAVGVAAYPTRHPESPSEAHDVEVLL
AKQRSGADFAITQVFFHTEQYADLVTRARRAGVTIPIIPGVMPLTSLRRLKRLGELTGVE
PAPELIERMAAADTDAERLRIGVSATVDLANAALDAGAPGLHIYTFNEHQSALEVLDKLS
LARPARPSTRLNALARRQLAS
>G7G9Z4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acinetobacter sp. NBRC 100985|TrEMBL
MTKRVPISFEFFPPKTDAGAEKLRVVHQELQLLNPEFFSITYGAGGSTRERTLAAIDDFN
GKGTPVAPHLSCIGDDKARIAELLDLYKSQGIDRIVALRGDLPSGQVGLGELPYAQDLVR
FIREHSGDHFHIEVAAYPEMHPQAESFDADIKRFVEKVQAGANAGITQFFFNPDAYFYFI
DRLEKAGVNIPVAPGIMPITNASNLIRFADGTGAEIPRWIRKQLAAYGDDSASIKAFGHE
VIVKLCERLIAGGAPTLHFYSMNQTEPTRQLVVDLGLN
>A0A0Q9A6M4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. Root901|TrEMBL
MKVTEHIENAKGKTLFSFEIIPPQKGKSIQELYDNIDPLMEFKPPFIDVTTSREEYIYID
RGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTQEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFTPKAGGNHYAIDLVRQINNLNCGKYLHEVMDVDNKADFCIGVAGY
PEKHLESPSLQSDLKRLKEKVDAGADYVVTQMFFDNAKYFNFVEKAREMGITIPIIPGIK
PIAVQRHLQILPQIFRIDLPEDLIDAVDKCKNNAEIKQVGIEWAIQQSLELKAAGVPFLH
YYSMGKSENIRQIASQVF
>A0A350YTL0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidales bacterium|TrEMBL
MSGIKPARRWQPPFYPFKRESFGKRFREKIEIIVKGPVWGCRMCGNCLLQETAFICCMEC
PKGLRNGPCGGVTPDGHCYVDPTRRCVWHAIYFRARKTGREDTLLEVLPPLDWSRAGTET
WADVFNQIGKVGAGRFIGSLFSRDKELKKQVWNSVFKTVRQPVWWNGDSEYHAAAYKEPV
SELEKSLREGRFVVATEVTPPLSADSGKLKNDIELVRPYVKAINFTDASSAIPKMSALAC
CKVAVDLNAEPVFQIAARDSTRISLQADAIGAGQFGIKNILCVTGDSPVVGPPPSSDMNI
NDLDSVQMLWILRRMRDEGIYLDGRKMKHPPSYFLGAATTPFALDPELQAIRDQKKVNAG
AQFFQT
>A0A6L7EY18|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nocardioides flavescens|TrEMBL
MTDRRGRSIRELLDEGDRSFSFEFFPPSDEAGEEQLWKAISALEPYDPSFVSVTYGAGGG
TRDKTIGITSRIARETSMTPVAHLTCVGHTRAELQGILDAYAREGVRHVMLLRGDPQEGP
RAEWTPTEGGLTYAQELVELVAGRGDFRIGVAAFPEGHPSAASLDADADVLVAKARAGAE
FAVTQMFFRADDYFALVRRVRDRGVDIPILPGIMPILNLGAIRRQSELIGTEVPDHVVAR
IAENDGDAAAMRAAGIDAAAELCDELLAGGAPGLHFYTLNRSKATLEIFERLNVTV
>A0A5C9E581|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thorarchaeota archaeon (strain OWC)|TrEMBL
MSSMVCGHILLNAGIEPIIQMSARDRNRVLFQSELYGAHALGLENVLFITGDHTLLGSHP
KTKMVYDIDSIQALQLAKHLMSGKDLAGADLEGTPQFFLGSTFNPYADPMPLQAMRVSKK
KQAGAQFFQTQAIYDIPRFEKFLSHIPVEDIKIIAGIIPLKGPKMALFMNQRIPGFKIPD
TMIHRLEMAGNGLAGLDKRTAIRAEGLNIAVETIEQVRELPGIDGIHIMAVGWEESLPEI
VKRSGLLPRPR
>A0A6P8K2X3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Drosophila mauritiana|TrEMBL
MHAIQVPAGGSSPAAASYIPCVTFAPDQNETSVTEQRIGTLVAERTAQRRLFYGIEVMAS
DPSGRPTCLDFNHFLPLLPTFVSVVWLSQRYWDVQPVGQVESLHLAHHLATRIPVLPHVS
AYRMSRQRLDQILALNFSSLLAVRGDQVHEDQDFSISYPMVEHSRRQRGETISVCVGGYP
EGYTSLGDIPQNSAKNMEFLKAKIDAGADCIITQICYRPEVIVQFVKDCRAAGIAVPIVV
GLMSHESFRSYSMIEQIAGVHLPDDLREQLDHLHSAHMMDMKSDQDLIRRFFVSLTVRTV
RHVLDADVGIWGFHFFTLNRFKSVQAVLQELRDLDLLKDAEKDTKGYEK
>A0A1X9SMU7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Campylobacter lanienae NCTC 13004|TrEMBL
MLKDKIKQGRSGIILYGLTPPKISLSEDKAKEIALKQLQRLEGIKIDGLVIYDLQDESSR
NSDNRTFEFVRTINPEIYAKDYLQNRYESVIYKAVGNYDKSEFRDFLLSHSNAISVFVGA
SSASDTPRLALNEAYKMKKEIANTLTLGGICIPERHMKKNNEDLRVASKRVKGCEFFITQ
AVYDIETAKKFLDDFAVLGIKNTPIIFTFTPCGNEKTFEFMQWLGISISELSKRRIFDSN
DPLENSVKLSLDMFEFLYKYGQTKGVSVGANVESISTRKVEIEASIKLLKGIISIVENDS
LENTKSKIQSASRFDE
>A0A2S1R6D5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dietzia lutea|TrEMBL
MTQLPDPDPTDGGRHPSIVERIATSTTPRVPFSVEFYPPRDEAAEERLWRAASVFSELGA
AFVSVTYGAGGSTRDRTVRVVERIVRETDLVPIAHLTAVGHTVAELADMIRMYGEAGVSN
ILALRGDPPGDPLGEWTAHPEGLRYAEELVRLIHEVGDFHVGVASFPEGHYRARDLDHDT
EVLVGKLRAGAEYSITQMFWDVEHYLRLRDRAVAADPEQGAKPIIPGLMPVTSLRQVKRM
VELSGCALPDDLAERLRTAAGDGPEENREAVREVGIDLTTRMCERLISEGVPCLHFNTLN
FSRATREVLTNLSMAPAPGVAASRV
>A0A520A370|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pedobacter sp|TrEMBL
MKIIDHINNAKGKTLFSFELLPPIKGQSIKGIYDAIDPLMEFNPPFIDVTYLREDYIYK
>A0A0R1LLI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Levilactobacillus acidifarinae DSM 19394|TrEMBL
MGPTKPELSFEVFPPSSPAGTIKLTQTLTQLKGITPSFVSVTCSNHQLDYEQNTIALAQT
IRQDLRCPTMVHMPAAYVTKAQVRRILAQLETAHIDQVLALRGDLDGTAPESDFAHASDL
ARFIKQVNPHFRVTGACYPEVHPDSQNRVDDVRHLKTKVDAGCDQLITQLFYDNAQFYRF
QEACALAGITVPILAGIMPITNRQQALHVVQNCAASLPPKFVAILDKYRTNPVALREAGL
AYAVDQIVDLVTHDVAGVHLYTLNQAATAQHIYDNTASLFAPVAVDD
>A0A4R3K3G6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectinatus cerevisiiphilus|TrEMBL
MNISVELVPRTEKDLREELQLMKDKAFPIDLINVPELLRFAIHGWEGAAIAQEYGFETMP
HIRALDIDLTRELPMKGYLQKRKIRKVLAITGDPPQSMATKVYPTISTDIIRKFQQEMPE
VEVFAGIDQYRSSMRQEMYMVRRKLQAGAAGFFTQPFFDLRYMEMYAELLDGLDVYWGIS
PVLSENSVSYWKIKNNVIFPKDFEPTLEWNIDFACKVKEFVKKAGGNMYIMPIKTNLEKY
MNSIFMCTK
>A0A654DLD0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingomonas sp. T1|TrEMBL
MTTITIPQLAEARRALEEPLFADLAGDVGISFEFFPPKSDKMDAQLWDAIRTLEPLGPDF
VSVTYGAGGSTRERTHATVARIQRETSMNAAAHLTCVEATKAEIDQVAEEYWAAGVRHIV
ALRGDMPTLGQPYQAHPGGYENAAALVAGLARLHPFEISVAAYPECHPESGGHDVDLDNL
KRKLDAGATRAITQFFFSPEAYFRFRDRVAAAGITAQILPGILPVSNVAQTRKFANACGA
EIPAWMDRLFEGLDDHPAARQLVAATIAAEMCRRLYAGGVKDFHFYTLNRAELAYAICHM
LGVRAKPSEKVAAA
>A0A2W2A6G7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Taibaiella soli|TrEMBL
MKVTEHIRQATGPIISLEILPPTKGKSIDSIYTVLDKFMDFKPSFINVTYHRAEQVFKKR
GDGSFERVEIRKRPGTVGICAAIMNHYNVDAVPHLICGGFSKEETENALIDLHFLGIKNV
LALRGDAAANEKFFTPHPNGHRYAEELVRQIGELNQGRYLEEDIMDGVKTDFCVGVAGYP
EKHFESPNVEMDVYYLKRKLDLGADYVTSQMFFDNKHYYNFVNNCRAGGIEAPILPGLKP
ITNKRQLSVIPSIFNVDIPMELTKEMLAAKTDAACEQIGQEWLLYQCRDLLKNNVPVLHF
YTLGKPHVVENVLKQLF
>A0A0R1S809|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus diolivorans DSM 14421|TrEMBL
MSLTALFKNKTVFSLEVFPPKKDSPKEAILPTLQQLQSINPDFISVTLGAGGSDHYTGTV
QIADLIQNQLNIPAVAHVPGLYQTREQVLNLLDNLSEINVKNILALRGDKIPGKQPVGDF
NHANDLVAFVHQNRPDFSIASACYPNCHAEATGFVDDIAHLRTKVDAGADHLISQLFFDN
QAFYDFQEKAEIAGIHVPIEAGIMPCTNKKQIERITQITGVPLPKKFSAILDRYQNSKEA
MRDAGIAFAVDQIIDLVSEGVDGIHLYTMNHADIAERIWNATKSVFDAANARTRTTIKHR
S
>A0A2S7VLT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Photobacterium angustum|TrEMBL
MSEQYQPTPESELRVRYNDITRGVYFIGTTPPKTSTPIEDVEGIADRLVDRIRDLAIDGL
IVYDIQDEASRTNKPRPFPFKSTHDPRHYSSLLNKKTDRPVITYKSVVQSETEAFDEWLN
EAWDEYRVRDMVLVGSPSAKNDVSLPLSTAYQTLAENRNDFFTGGIMIAERHAKKGNEHE
RLIEKYKQGCNFFISQAIYDTQATIDILTRYAIECKEQGLKPQRIILTFSPCGSAKTLEF
IEWLGVSVPEATSLRILNAENPLHESIKMCCNSLNQILDAVVEYDLPLGLNIESLTNRKE
EIDGSILLYKLLRSSMDSHLAKHEFRLLKRKARANKLASA
>A0A495RVT8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingosinicella microcystinivorans|TrEMBL
MILTLDQMTEAQNAVRQPLFADLKGDIGVSFEFFPPKTEKMEETLWDSIKALEPLRPRFV
SVTYGAGGSTRERTHATVSRLVRETTLTPAAHLTCVDASRGEIDDVARAYWDAGVRHIVA
LRGDPPRAGERFVPRADGYENAAALVEGLRRVADFEISVAAYPEMHPEAASIAQDLDNLK
RKLDAGAHRAITQFFFEPETYFRFRDHAAAAGLNAEIVPGILPVSNFAQTKRMAEMCGTA
IPGWMGRLFDGLEERPAARGLVAATVAAEFCRRLYAGGVREFHFYTLNRADLSYAICHML
GKRAA
>A0A328NDB7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Micromonospora noduli|TrEMBL
MALGLPSTLPNPQPAIGELIREHQPTFSFEFFPPKTEAGEQLLWQAIRELESLRPSFVSI
TYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHVVGRLAGVGVRNVLAVR
GDPPGNPGGEWIRHPEGVDYAEDLVRLVRDAGDFSVGVAAFPYKHPRSPDVASDTAQFVR
KCRAGAEFAVTQMFFDAVDYLRLRDRVAAAGCDTPILAGVMPVTQFSTIERSVQLSGAPF
PPALAARFERVADDPDAVRRLGIEQASEMCRRLLDEGVPGIHFITLNRSTATREVWQNLK
AGARV
>A0A1E4DKF9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrospira sp. SCN 59-13|TrEMBL
MSREPRRLKDVLAQGQFAVTVEYNPPKGTNLTHVVESAKSLVGRVHGVNVTDNTAAIVRA
GSLPVCRILYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGIRNILCLTGDYPTVGDHKD
AKPVYDLDSVQVMQLVTGLNNGKDYAGNKLDGSTDFTIGGAVTPEADPLGPMLVKFEVKV
RAGAQFFQTQAIYQPEQFKKFMDAVRQFKVKVLAGILLLRNAKMAEFMNANIPGVCVPQE
MIDEMRAAGDKRALDAGVEIAVRTIKAVRPYCDGVHIMAIKSTERLPEILTKAELG
>A0A4V0IFK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinobacillus indolicus|TrEMBL
MSYAREIDLLNQSVADLNGKINVSFEFFPPKNEKMETMLWDSIHRLKVLKPKFVSVTYGA
NSGERDRTHSIVKTIQQETGIIAAPHLTGIDATPDELRAIAKDYWDSGIRHIVALRGDEP
PGYTKKPFYASDLVTLLKDVADFEISVAAYPEVHPEAKSAQSDLLYLKQKIDAGASRAIT
QFFFDIDSYLRFRDRCATVGIDVEIVPGILPVSNFKQLEKMAKITNVKIPSWMTKMYQGL
DDDQTTRNLVGASIAMDMVKILSKEGVKDFHLYTLNRSELSYAICHTLGIRPE
>A0A6P0XYI0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Okeania sp. SIO2D1|TrEMBL
FACRDRNRIGLQADLLGAQALGILNILALTGDPVKAGDHPDARAVFDLESVRLLQVITRL
NSGFDANQQPLPDGPTNLFPGAAVDPQIKFSALARRFERKLEAGAQFFQSQLITDFDKLD
KFMNQVAAGTDKPILAGIFLLKSAKNANFINRYVPGVHIPPEIITRLAAAERPLEEGMKI
AAEQVKLAKQLCHGVHMMAIKKENLIPQILDLAGIDPID
>A0A6G9EMF1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni|TrEMBL
MKKVSEIYGSAKGPVYSFEFFPPKTPEGDSKLMETVKELSLLNPDFVTVTYGAGGSTRDK
TVQILSQISKDYSFPTVSHFTCVGANKNQILETLKGIRSSGILNLMALRGDPPKGEGEFK
KVENGFGNATELVSFIRSEKLDFCIGGGCYPEKHPNAKTLEEDVENLKLKVDAGTDFLVS
QLFFVNSIFENFLNLVRKVGIQVPVIPGIMPITSFSQIDRFRSMAGCEFPSSLIQDLQEV
EHRPEEFYRRSLNFSVKQCRELLAMGVPGIHLYTLNQSHASYDIVRELKGESA
>A0A6I8MI90|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Corynebacterium rouxii|TrEMBL
MSAQPLPAAYQRTITDVISMPTPGQVPFSVEFMPPRDEAAEERLWKAAEAFHDLGASFVS
VTYGAGGSSRERTMRVAHKLSRHPLTTLVHLTLVEHTQEELEEILCTYASHGLSNLLALR
GDPPGTDPMAPWVPTAGGLDYAKDLIDLVRKTEQTSHFQVGIASFPEGHYRAPSIEVDTQ
FTLEKLRAGAEFSITQMFFDVDHYLRLRDRLVKADPEHGSKPIIPGLMPITSLRSVRRQM
ELAGATLPEALEKRLLDAARGDEEAHRDDIRKVGIEVTTEMAQRLISEGVPDIHFMTMNY
VRATQEVLHNLGMAPAWGTQQGHDAIR
>A0A6G3RYW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. SID14478|TrEMBL
MAFGTASTRTDRARTVRDMLAAGKTTYSFEFSAPKTAKGERNLWNALRRVEAVAPDFVSV
TYGAGGSTRAGTVKETQQIVADTTLTPVAHITAVEHSVAELRNIIGQYADAGIRNMLAVR
GDPPGDPMGDWISHPEGLTYAAELVELIKESGDFCVGVAAFPAMHPRSADWDTDVRHFVD
KCRAGADYAITQMFFYPEEYLRLRDRVAAAGCDTPVIPECMPVTSVRMLERLPKLSNADF
PPALKERILTAKDDPAAVRSIGIEFATEFCAKLLDEGVPGLHFITLNNSTATLEIYENLG
LHDQQA
>A0A0B2WYR0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Metarhizium album (strain ARSEF 1941)|TrEMBL
MHIKDMLVEAEKGGQPSFSFEYFPPKTSQGVQNLYDRIDRMYNFGPKFIDITWGAGGRIA
ELTCEMVLQAQSVYGLETCMHLTCTDMGLDKVNGALQKAYKAGCTNILALRGDPPRAQEK
WTAAEGGFHYARDLVKHVRATYGDHFDIGVAGYPEGCDDNKDEEQLLDHLKEKVDMGASF
IVTQMFYDADNFVRWVGKVRERGINIPILPGIMPIATYASFLRRAKHMQCKVPDHWMTAL
EPVKNDDVAVREIGKTLVAEMCRKLLANGIYHLHFYTMNLAQATRMVLEELTWAPCAERP
LQHALPWKQSKALGRRDEDVRPIFWRNRNKSYVLRTQDWDEFPNGRWGDSRSPAFGELDA
YGIGLTGTNEANRKKWGEPTTVQDIANIFVKYLNQEIESLPWSEAPLTGEADAIKDNLIQ
LNKRGLLTINSQPAVDGVKSSHPIHGWGPSNGYVYQKAYLELLVPASIFTEMVKRIENKP
TLTYYAVTKDGELRTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWRDEAFRLGTDW
AHCFESETPSRLLLDQIMNEWYLINVVNNDFHENQTIFDLFDGLEVRGLDTPATG
>A0A369QJU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Adhaeribacter pallidiroseus|TrEMBL
MKVTEHIANATKTLFSFEILPPVKGTSIQSIYNGIDPLMEFKPPFINVTYHREEYVFKER
ENGLLEKISIRKRPGTVGICSAIMHKYNVDAVPHIICGGFSREETENALMDLNFLGIDNV
LVLRGDSIKTETQFRPHPDGHAYASDLLKQICDLNNGNYLDEDIANPVPTNFCAGVAGYP
EKHSEAPNLEIDLKYLKMKVDMGAQYIITQMFFDNQKYFNFVKACREHGINVPIIPGIKP
LTVKNQLRMLPNLFHIDIPNDLVQAIDSAPTPQAVRQVGIEWATQQCKELVQFGVPCLHF
YTMSKSEATAAIAKEIF
>A0A167SDQ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calocera viscosa (strain TUFC12733)|TrEMBL
MKITQKLAQAEHEGRVWWSFEYFPPRTAPGMQNLLDRIERMREFGPEFIDITWNAGGRTS
ELTSELVRCCQRDLGIETCMHLTCTNMPAEKVDIALKEAKQWGCRNVLALRGDPPFGQEE
WTKTEGGFEHGIDLVKHIRESHGDYFDIAVAGFPEAHNRPDWEVEMKFLKNKVDAGVNFI
FTQMFWDVDLFISWVKAVRAAGITCPIVPGIMPIQTWNGFQRATSLAKITIPDSLLAQLE
PYKNDDEKVREIGTQIVADMCRKILASDIGIRGLHFYTMNLERGTRMLLEALNFVPHIEV
VRPLPWRQALTPTRRGENIRPIFWANRVKSYIHRTENWDEYPNGRFGDSRSPAYGELDGY
GIWIKQTPEEGRKIWGEPTTFEDVSELFSKFCNGELKSLPWSDTAPASETTVISKELARL
NEMGYLTINSQPAVNGAKSTDPVHGWGPRNGYVYQKAYLEFFVDKKKFEELVSRIERDPM
ITYYAIDKHGNLRTNNHSDGPNAVTWGVFAGKEIIQPTIVEAVSFLAWKDEAFELGMQWA
HIYEPGSVSRKLLESIMETFYLVNIVHNDFQDPKAVFGPFGVDAKKANGTANGGAHALPN
>A0A3M9N9X2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hanamia caeni|TrEMBL
MKVTEHINGAKETKISFEILPPLKGKTIESIYNHLDPLMDFKPAFINVTYHRSEQVFKKK
PDGTFEKIEIRKRPGTVGICAAIMNHYKIDAVPHLICGGFNVQETENALIDLAFLGIDNV
LLLRGDASKNEAVFEPEENGHAYAIDLIKQAVNLNHGIYLEDDIRDGNKTNFCIGIAGYP
EKHFEAPNLQSDLNYLKMKVDAGADYITTQMFFDNNKYFEFVKNCRAIGIQVPIIPGLKP
ITSKKQLNVLPRIFHVDIPNELSNEIIKCKTDAEVEIVGTEWLLQQSKELKKAGVPVLHY
YTLGKPHVVVNVAKQIA
>R5YD56|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:212|TrEMBL
MKIIDKLNEDRIHISFEVFPPKTDAGFEKVKDATDKIAQLNPSYISVTYGAGGGTSKNTA
KIASHIKHELGVESLAHLTCASSTKEEVRQVIENLKQLEIENILALRGDIVPGMTFPSED
RFHYAYELVEEIKKHGDFCIGAACYPEGHVENEHKEDDIKYLKQKVDSGVDFLTTQMFFD
NDIHYNFLYRIREAGITVPVLPGIMPITTAAQMKRSQELSGTVFPRRFLALLDRFGDYPD
AMKQAGIAYATDQIIDLLANGVKNIHVYSMNKPEVAAKIMENLSEVIKC
>A0A6H9KV86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MKTSFLDYLQENIIIGDGALGTLLYGKGIPMTHSFDELNISRPALIKETISEYVRAGAQA
VETNTFTANRHKLNRFELGHRVEEINVRGVDIARAATQGEAYVLASVGPVRAGEIDEITD
DEVKAIFAEQIGTLDSAQPDAIILETFARASELEIALATALQITKLPVIAQISVDETGAT
RDGQHIVPVFKKLRKMGANVVGINCAKGPSAILHALEQVPLSKGLLLSAYPNAGLPAYVD
GRYLYLSTPDYFGDTAWRLRDQGVRLIGGCCGTTPEHIQAMAKALDGMQPVKRKSVLVKA
SRSGIPEKIIDSRPGVLDYVKERPTFIVELDPPRGLNYQKIVAGAEALKLAGADAITMAD
SSLGVTRMSNLALGHIVQQETGLMPLIHLACRDRNLIGTQAMLMGLHAFNINYVLAITGD
PAKVGDQPGATSVYDLNSFNLVRMIKQMNKGIAFSGRRMDQATDFKVGVAFNPNSQRMDA
QVRRLEKKVQFGADYVMTQPIYDPKQAKMLADIAANFDIPFFIGIMPLVNQRNAEFLHHE
VPGITIPDFALNRMKGLEKEAGQVEGIKIAAELQNEILSYFKGIYLITPFVRYEMTTELI
ELARAV
>A0A7J4S4T8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MTAEIAPPGSADPMEVRRIAALLRDSVDACNVTDCQRAMVRMSALAAAVLAMQEGVEPVL
QMVLRDRNRIAIQSDLLGAAALGIRNVLCLRGDPTQIGNEPSAPGVYDLSTEELLSTCRD
LRDRGVLRGGDAIDVPPRLLLGASANPFAGGLEESFANLRGKVTAGADFIQT
>A0A3Q8S534|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus lentus|TrEMBL
MRPNLRVRMQEEVLVGDGALGTYLYQLGFPVGISYEEFNLLRPEVIGDVHRRYIEAGAQL
LETNTFSANYYKLAKFGLESKVEEINKAAVRIARSAAGADAYVAGAVGSIRGGKRVNVSV
QELNQFYEQQISALLTEDVDALLFETFYDLQEMRIALGKARKSTPIPIICQFAVDQLGRT
LDGYSIKEAFGILREEGADVLGFNCHSGPKGIMSVMEDLNGPLDIPLSVFPNAGLADYVD
GEYVYGATPEYFGESAVSFADLGARLIGGCCGTTPEHVSAIAEALSNYAPKSLQEGTALP
PVQPSIIVEEPETSIKDAFSGQVSDPSIVELVKERHTVIVELDPPRDLDIRKFMDGAAAL
KEAGVDALTLADNSLAVTRMSNMALGHLVQSEVGLRPLIHIACRDRNLIGTQSHMMGFDA
LGIDHVLAVTGDPARFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKAKFVVG
AAFNPNVKHLNKAVERLEKKIASGADYIMTQPVYDPELIVAVKEATAHLDIPIFIGIMPL
ASGKNAEYLHNEVPGIRLSDSVRKRMEGLQGEEGRKVGVEIAKELLDTALEHFNGIYLIT
PFMFYEMSVILSNYVWEKTAPRPCHLSRS
>A0A7J4UZH3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmata archaeon|TrEMBL
MKTGSNLEKVFESGKFAVTAEIGPPQSANPEPLTHHAKMLKGYADAFNLTDNQTAVVRLS
SIASAVIIMREGIEPVIQMTCRDRNRIALQSDLLGASALGIRNVLCLTGDHQIFGNEKAS
KSVFDFDSVSEISVFDKLRREGKQAGGQEIKDPPKVYLGCAENPFATPYEFRATRLAKKV
AAGADFVQTQAIFDMDMFEKWMDEVRARGLDKKVHILAGVLPMKTAGAARYMKNKVPGMI
VPNQIIDRMKNAKDSKEEGIKLCVEQIETLKAMKGVHGVHIMAVMWEEMVPRIVEEAGLL
PRPSIE
>A0A1F4HAW1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFCSPHIGHO2_12_FULL_61_11|TrEMBL
MNVPVSFEFFPPKTPEGADKLRLTRQALYAHKPEFCSVTFGAGGSTQEGTFGTVKEILGE
GVAAASHLSCVGATRAAVRQHLATLQAMGVKRLVALRGDLPSGYGLGGEFHYASDLVAFI
REQSGNAFHIDVAAYPEIHPQARSADADLQAFVAKVKAGGNSAITQYFFNADAYFRFVDD
ARALGVDVPVVPGIMPITSSMQLMRFSDACGAEIPRWIRLRLQGFGDDAASIKSFGLDVM
TDLCDRLCVAGAPGLHFYTMNHAAATTEIIQRLRRAKPGNGS
>A0A2G2ISM3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Leeuwenhoekiella sp|TrEMBL
MKITDHIKQANGKTLFSFELIPPRKGRSIQELYDNIDPLMEFKPPFIDVTTSREEFVYIE
KEDGLLDKKITRMRPGTLGICASIKHKYDVDTVPHVLCG
>A0A1Q5Q3T6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bowdeniella nasicola|TrEMBL
MPWEALRSSAARSCSRSFSAPAELVELIREVANRELGDPAAVSVAVAAYPAGTIQTRTDA
VAALVDKQSAGADFAITQVFYRAVNYRDLEQAASYQGVRLPIIPGILPFTDINRLQRLQA
LSGVAVPPELAALADLPDPGERLRATLAATLGFLDELLSYGAPGLHFYTFNRARPTFDLV
EHLRSRKFAPVDAAESAALLELASVNLTRPAP
>A0A436EX87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. M7A.F.Ca.CA.004.05.1.1|TrEMBL
PQLFLGAAINPFAPPIDFRPHRLGKKIAAGAQFVQSQYCFDVPMFRSYMQKVRDLGYTEK
CFILVGVGPLASAKTAKWIRSNVPGIHIPDSVIKRLEGAQDQKKEGKQLCIDIINEVKEI
SGVSGVHVMAYRQEEYVAEIVDESGVLKGRQPWKREIRRDDQLVADRLDSILHDDITETQ
VDMVKTAH
>A0A3M1XU85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MKVLDALNAATKPIVSLEITPPDKGRSIDELFVTLDHLMKYEPAFIDVTYHQPHVVYEER
DGVIYRVPKRKKPGTVGICAAIKNRYGVEPVPHFICGGFTKFETEDALIDLHYLGITNIL
AIRGDPPPGHRTFIPEKEGHRYASELVHQIANMNRGIYLEELEDAEPTNFCIGVAGYPEK
HYEAPSFEKDLQNLKHKVEQGAHYVITQMFFDFQVFKRFVEQARDMGITVPIIPGVKPLT
RVNQLVSIPRNFYVSIPHHIVEAMEAAKTPDAARKVGIAKTVELCEQLLDFGVPGLHIYT
MGRGNATAQVLHALLG
>A0A3M2FJW0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Calditrichaeota bacterium|TrEMBL
MKVTEHLNNTDKTLISFEIIPPKRGGDIKSLLNLVDELARFDPPFIDITSHAAEVIYEET
PQGIQRKTKRKRPGTLGICALIQKKYNIDAVPHILCRGFTREETEDFLIDLQYLEIENVL
AVQGDDTSYKKPIPDGRTTNKFAVDLVRQVNDMNHGIYLEENLLDAKPSNFCIGVGGYPE
KHFSAPNLDTDIRFLKEKVDAGAAYIVTQMFFDNSVYFNFVDRCREAGITVPIIPGLKII
TRKSNINSLPRTFHIDLPLELSNRILDASPEDVTEIGMDWTLKQARELMEKNVPALHFYV
MQNSTPIKKLLKRLTDG
>H0K4F8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Saccharomonospora azurea SZMC 14600|TrEMBL
MGLKDRARGRGPAPRLPRRWLDEARFEVLPLDAVLDETAHLPENTTVTVTASPTRGLDAT
VQLCEKLAAQRLRVVPHLAARQVRDATHLRDVLDRLAAVETDEVFVIAGDASTAAGPFGD
GLSLLRAIEESGRRPRRIGVPCYPEGHPTVPDDALWEALRAKQPHADYAVSQLCFDPGVV
CRFLRAARQRGVTLPVLVGVAGVVSPAALLRVGSRIGVGDSLSFLRANRSTVAGLVSRHD
PGRFLAGLADRAADGECAPAGLHFYTFNRVSATTAWLTAVRGSRTE
>A0A2N1JJB2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinomycetales bacterium SN12|TrEMBL
MSSIPFSFELYPPRTAESARALHDTIDRLAEAGPDFISVTYGAGGSTGGRSLEVLRYIRT
HTDTEPLAHLTCVGNTYAGAARLIREFLDAGVLSFLALRGDPPAGQSEDDAFLGDLESSA
QLVQLIDRVQAERAPYEESPVRGNPAAVRVAPRRRVNIAVAAFPNGHPRSAYSSQHVDAL
LAKQAAGATVAITQLFFHPDHYLAFVERARRAGVTIPILPGIMPITSPARLARVLELTGE
ELPSELAIELEIEPTAEGRRQIGIRWAADLIRAVVDGGAPGVHLYAFNQHETVLDVLQSA
GIIPARQLSAASKGTP
>A0A7K3ZJI6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thermoplasmatales archaeon|TrEMBL
MTGSLLKEKLERGEFAVTAEIGPPKSASGEDILARAKMIKGCADAYNITDNQTATVRLSS
LAGSVFIMKEGMEPILQMTCRDRNRIALQSDVLGANALGIRNILCLSGDHQCFGNQPDTK
NVYDVDSTQEIMIFKRMRDEGTLWSGDRLKVAPDLYLGAVSNPFGDPREMHVMRLRNKVS
AGAQFIQTQSVFDLDAFESWVSEVRRDVSLKDVKILAGMLPLRTLKAARYMAESVPGTCV
PPEIVRRMAAAPDEEKEGQRIASEILDGIRDMKGVSGVHIMPVNWYSAVRPLLERAGLLT
GHSLR
>A0A7J5C2M2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudoclavibacter chungangensis|TrEMBL
MAERIEIVPVAGVVDEVRRRLPVGTTVTVTALPAHGIEPTVAASLELARHGFDAVPHLAA
AQIPHLGTFDAIMDRLADSPIRTVFAVGGDGVTPQHAVPDGLVLLERIRETTDDRFRIGV
AAYPEGHPAFDTSRGIEVLRRKAPLADHAVTQMCFDGARLGRYATELATAGVPLPLWFGV
PGRVGVRKLAGIAMRIGVGRSLAFAKRGANRRLLGAYDPSALRADALATLGTTAFAGFHV
YSFNAFDGLGALVADQSAS
>A0A7Z0J0S0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MIAPQSESREKAPLADLLSHYSIEVTSRDLPSLQSMTATLPPGSEVFVAHLPKEDIGLLV
RAAAGLRDAGFVPVPHIVARNIRNRPELDTMLARLSEEAGVRHALVLGGDRDDAAGAFSS
ALDLIETGLFQTYGIGRIAIACYPEGHPRIAGAVLDTALTAKVDAAARAGLDLLLVSQLL
FDQKPLLSFARRLRERGVTVPLRVGIAGPAGRTKLLKYALRCGVGASLRALRERSEIARN
VLSGETPEELLIDIAAAQTAEPDLGISGVHFFTFGDPAQSIRWAEQQQPSD
>A0A1M7G0G8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Caldanaerovirga acetigignens|TrEMBL
MENCFKKSLLSKNLFSVTWELVPGRGAREKSIEEALEAAEAAAKGGKVHALTLTDNPGGN
PAMLPDYLAVEVLKKGIEPLVHFTCKDRNRSQIESQLYALDRAGVRNLLVMTGDYPVSGY
AGRPRPVFDLDPIHVLDLISQMNRGLEYKGIKGTVKHQPSDFFAGAVVSPFKATEAEQVV
QYFKLKKKVRAGAQFIVTQLGYDARKFHEVIQFIRQQGWDIPVVGNIYVLPLATARIMNK
NKIPGCVVTDKLLAKLEEEAQSSDKGRQARLDRAAKMYAFMKGMGYDGVHIGGHNVKYED
VEYIIEKGEELSKNWMDIIHEFDFPIPGGFYYYEKDEKTGLNRPEPVSRKNRPLDAKVEF
VYPLSVLTHKLMLEPGAPLWGLMRGIAKRIDGTSLERPYHTFEHLTKVCLYDCHDCGDCA
LMDLAYVCPMSQCPKNQRNGACGGSYMGWCEVYPNEKKCSYVRAYARLKRYGKEKELDGD
IIPPSNWDLFQTSSWLNYYLGRDHSAKKLGIEQVAKKKK
>A0A7W5SCD6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium sp. BK602|TrEMBL
MSSRTENGQGNIRISFEFFPPKSEEAEVQLWNTVADLSDWQPEFVSVTYGAGGSTKAPTL
AAVRRMIHETPFTTASHLTCVGATREDTHRVIDDFLAAGVRRFVALRGDPPGGVGSAYQP
HPGGYANAAELVAALRERGDFDISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDAFERYHDRVRATGIKIPVVPGIMPIQNLTQLKRFAGACGTSIPTWLDERFDGIDD
NSEARAEVAADVAAEQIQDLVRRGIHEFHLYTMNRSPLVSAVLERLGIQRRTDAPAGAAA
>A0A8J2BVR8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Methylacidithermus pantelleriae|TrEMBL
MANILQELEQRIVIGNGAIGTYLYALGIPRGFCLEALNLTRPDLVTKVYQDYVAAGARVL
ETNSSGANPIGLSRYGLSDQAVQLCHKAVELVRKVVEGKPCFIAGTTGPIVLRSTEPPIS
VEERREAYRVQIAALWEAGCDLLLLKTFTDLADLLLAIRTAKELGVHPIWASVAPTEEGR
LSSGEDVGEALASLRQAGASIVGVNGACGVQATLHLLEQLELEASDLVSAFPNAGKPEFY
EGQLFYGASPQYFASYLPRFVAEGARLIGGDYGTDPSHIAAMVAVAGSLRPVGAKPRRRR
VFLREPTEEGPSRGFSWREESLLERLKRKTVSIVELDSPKTLAMERFLEGVSALEEAGAD
AISLADNSLAILRVSNVAAAVCVRQRSSLIPVLHIACRDRNLLGLQSELMGLGVLGFRHV
LALTGDPAKAGDHPGATSVYDLNSVGLIRLLAGLNRGVNAVGKDLKGKTDFVIGCAFNPN
ARQIESQRRKLESKLQAGAQFVMTQPVFDTRLVKETARMLGPLGVPVFIGVLPLLSYRNA
EFLHNEVPGIVIPEAVRERLLFLEGPRAMEAGLALAVEIAREILSHFRGIYIITPLLRYE
LSVRLLGQLGLSPGEMRVAKEKGKGAV
>A0A2K9Z5P5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium leguminosarum|TrEMBL
MVLKNDARGRNIRVSFEFFPPKSEEMEGQLWHTVSELQDWDPDFVSVTYGAGGTTRAPTL
TTVTRFLSQTPLATASHLTCVGATKEETHQVVDTFRKAGVTHFVALRGDAPGGAGAPYQP
HPGGYANAAELVAGLKEIGDFEISVSAYPEKHPESRDTAADIDMLKRKADNGADRALTQF
FFDNDNFERYLERVRGAGISIPVVPGIMPIQNLTQLKRFAGACGTIIPAFLDERFAGFDD
KPEERAKVAAEVAAEQIEDLVRRGIHDFHLYTMNRAPLVSAVLDNLGISRRETKSAGAAA
>G8UL82|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tannerella forsythia (strain ATCC 43037 / JCM 10827 / CCUG 21028 A / KCTC 5666 / FDC 338)|TrEMBL
METVIDLIKNSQRTAFSFEILPPLKGNSIQSVYQVIDKLREFEPKYINITSHHSEVIQRV
EPDGSIRTVNLRKRPGSVAIASAIQNKYGITAVPHLVCKGFTKDETEYGLIDLNFLGVNN
LLLLRGDIKRLDLTKDPKRCHDHATDLQHQVNDFNRGIALDGSAIEDIETLFSYGMACYP
EIHEEAPSMESDIRYAKMKVENGAEYLVTQMFFDNDKYDSFVARMRAEGVTVPIIPGIKP
IVFKDQLTVIPKIFHCTFPEPLTQALRQCKNDDEAKAVGIEWCIAQCRDLMKRGVPSIHF
YSFLASDSVRQVAKIIY
>A0A0R1VV47|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paucilactobacillus suebicus DSM 5007 = KCTC 3549|TrEMBL
MKTSECFKNQRPVLSFEVFPPRANASEKALDRFYHTLDILADLKPAYISVTYGAGGSNNQ
SSTLALVKYIRDHYGIEAVPHIPAVKFTKETVNDFLGELKASHIDNVLALRGDLPEHDDG
QRDFQYASDLVKYIKSVGDFNVLAACYPDVHPEAADAVKDIQNLKTKVDAGVSQLVTQLF
FENEHFYHFTERCELAGINVPIQAGIMSVINERQIKNMATMCGVGLPDKFAKMMSRYHDN
PIAMRDAGIAYAVDQMVDLLAHDVDGIHLYTMDNPIVAQRICDAVKTLV
>A0A7V8PHV5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pectobacterium versatile|TrEMBL
MSFFHANQREALNQSLAELQGRINVSFEFFPPRTSDMEETLWSSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWESGIRHIVALRGD
LPQEGGKPDMYAADLVSLLKEVGDFDISVAAYPEVHPEAKSAQADLINLKHKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTTMFD
GLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRPDVAR
>A0A2N5JGR6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carnobacterium maltaromaticum|TrEMBL
MGLKEVLGTKLLIADGAMGTLLYQYGIDRSHEELNCSHPEAILKIHQDYLAAGADIIQTN
TYGANYLKLARYGLEDQVQKINRAGITLAKEARGDKEAFILGTIGGIYGAVDTKIHDPGM
EEISRSFKEQLYCLLLGGVDGILLETYYDLNELKTVLAIAREATDIPIIANVSIHEIGVL
ANGQSLATALEELANLGADVVGTNCLLGPHFMAQSFESVPLIPGKVLAAYPNASFPTMEN
GRIVYQKETDYFKLFGELFRKEGVGLIGGCCGTTPEHIAAYREGLTTLDLVTQKKVKALT
TYTFQAKQETGKERLLDKVQREYTVLVELDPPRTFNTTAFFLGASRLKEVGVDAITLSDN
SLASARISNMALSAMLKYEYDIQPLVHLTTRDHNLIGLNSQIMGFHKLGIQDILAVTGDP
AKVGDFPGASSVFDVSSFKLIKLIKNFNQGIAYTGKNLREKTNFQVAAAFNPNIPRLERA
GRLLKKKQEAGADYFITQPIFDSEKVKILKEVMKTAGVTIPIFIGVIPLVSSRNAEFLHN
EVPGILLTDETRERMRMAEEEGRGLEVGMTIAKELIDEICQEFNGIYLMTPFMNYEISVE
LCEYIQAKKQQEKSGCSCGQVHSQ
>A0A8I0K498|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Carnobacterium maltaromaticum|TrEMBL
MGLKEVLGTKLLIADGAMGTLLYQYGIDRSHEELNCSHPEAILKIHQDYLAAGADIIQTN
TYGANYIKLARYGLEDQVQKINRAGITLAKEARGDKEAFILGTIGGIYGAVDTKIHDPGM
EEISRSFKEQLYCLLLGGVDGILLETYYDLNELKTVLAIAREATDIPIIANVSIHEVGIL
ANGQSLATALEELADLGANVVGTNCLLGPHFMAQSFESVPLIPGKVLAAYPNASFPTMEN
GRIVYQKETDYFKLFGELFRKEGVGLIGGCCGTTPEHIAAYREGLTTLDLVTQKKVKALT
TYRFQAKQETGKERLLDKVQREFTVLVELDPPRTFNTTAFFKGAARLKEVGVDAITLSDN
SLASARISNMALSAMLKYEYDIQPLVHLTTRDHNLIGLNSQIMGFHKLGIQDVLAVTGDP
AKVGDFPGASSVFDVSSFELIKLIKNFNQGIAYTGKNLREKTNFQVAAAFNPNIPRLERA
GRLLKKKQEAGADYFITQPIFDSEKVKILKEVMKTAGVTIPIFIGVIPLVSSRNAEFLHN
EVPGILLTDETRERMRMAEEEGRGLEVGMTIAKELIDEICQEFNGIYLMTPFMNYEISAE
LCEYIQAKKQQEKSICSCGQVHSQ
>A0A519N9L5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTEHIQNAQGKTLFSFEILPPLKGQNIQSIFDGIDPLMEFNPPFIDVTYHREEYEFKE
LENGLLQKKIVKKRPGTVGICAAIQNRYDVDAVPHVLCGGFTKEDTENLLIDLDFLGIEN
VVALRGDAIKSEMYFRPEIEGHNYATELVAQISNLNNGIYLDNDLKNVNSTNFCIGVAGY
PEKHLEAPSLDSDIYYLKQKIKNGAEYIVTQMFFDNKKFFSFVEKCRANGITVPIIPGLK
PISTKKQLNQIPHRFFVDLPDDLIMAVVKAKDNEAIKQIGIEWCTEQSRELVKAGIPVLH
YYSMGKAESIKAIAKEIF
>A0A2D6LGQ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Dehalococcoidales bacterium|TrEMBL
MKAGTNLEKVLESGKFTVTAEAGPPKGTSVASVQKKGELLRHCCDAVNVTDNQTAIVRMS
SLTGCLILKQQGIDPVMQMVVRDRNRLAIQSDLLGAVALGVGNVLCLSGDHQKFGNHPGA
KGVFDIDSIQLIQTLKMMRDEKKFLSGEDINGEVPLFIGAAANPFADPSEFRVSRLAKKV
KAGADFIQTQAVYDVDRFRQWTEAVVERDLDKQTHILAGVIPIKSAGMARYMRDSVPGVI
IPDEIVTRMEQATEAKEEGVKIILEVIEQLKEIPGVHGIHIMAVSWEDIIPEVVRKAVLM
PRPVL
>A0A355BDC7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
DAVKQIGIEWCIKQSKELVAAGVPCLHFYSMGKSDNIKQIAQEIF
>A0A4V6PJK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Companilactobacillus farciminis|TrEMBL
MTETNPTLSFEVFPPNSQVGVDNLTDTLDQLKGLNPSFISVTASNHKLNYEETTIDLAKY
VKDNLHCHTMVHMPAAYVTKAEVSSILNRLEKMNIHQVLALRGDIVDGYVPEKDFKYASD
LTQFIKTEKPNFTVSGACYPEVHPDSKNRIDDIRHLKDKVDSGCDQLITQLFYDNEQFYR
FQEECAIADINVPILAGIMPIVNRKQALHVIENCAARLPKKFINILDKYKDNPVSLKEAG
IAYAVDQIVDLVTNDVSGVHLYTMNKADTAKHIFKNTASLFNIESVIE
>A0A1W9NWF5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Cloacimonas sp. 4484_209|TrEMBL
MRIIELMKIKRPFVSLEFFPPKDQALWPRFFETVEKLKTVNPLFVSVTCGALGSGQEYTK
EITTNSILF
>A0A5F0F1N7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cryobacterium sp. TMT1-22|TrEMBL
MSTTSEPDCGRIPFSFELYPPRSDAAATALHATIATMASAGPDFISVTYGANGSSRSSSL
EVLTHILKTTTVDPMAHLTCVGSSSLEASRLIREFLDAGVRSFLALRGDPPEGAGEGEAF
LGDLGSAAELVQLIHRVQAERVPYRETVIPGIPGARAVKTEREKVRIAVAAFPNGHPRSR
STSQDIDTLLAKQAAGANLAITQLFFHADHYLSFIQRARTAGVEFPILPGIMPVTSPARL
RRILELSGEELPSELAIQLEVEPTREGQREIGTRHATDLARELIAGGAPGLHLYAFNQAD
TVLAVLAGAGLIKPVLG
>A0A2D8BQW8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Maricaulis sp|TrEMBL
MSATEKTNGGPSVSFEFFPPKTDEMADRLWESVSRLEAFAPGFVSVTYGAGGSTRERTHQ
TVKRIVDETRLKPAAHLTCVCATKDEINEVIREYRDAGVKHIVALRGDPPDGIGEKYQPH
PGGYVNAADLAAGISEIGGFEISVGCYPEKHPESASFEYDIDLLKQKVDNGATRAITQFF
FEPDTYFRYLDRVRAAGIDIPIVPGIMLQSNFKGLSRMAGLCGTSIPASLAARYEGLDDD
AETRELLTAQVAAELVQKLTDGGCEHFHFYTLNRAGLTMATCRLLGLTPAVAEPA
>A0A2S7QNU3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rutstroemia sp. NJR-2017a WRK4|TrEMBL
MEKITAKIAALPPDTSYFSLEFFPPKTSMGSSNLRARLDRMSRALRPLFVTVTWGAGGST
ATKSLELAELCQRDLGLTTCLHLTCTNMSRKLVDQALEDAKALGIRNILALRGDPPRTDE
YRAVDEKDGESPAMDWDFEWAIDLVKYIRKQYGDYFCIGVAAYPEGHADEGHPEGQSLEH
DLPYLVEKVQAGADFIMTQLFFDVEAYDHFEKRLREHPSGAFKDIPIIPGMMPIQSYQMI
KRTTKLSHAKLPTDIVTRLDTVKGDDEMVKKVGVDILSEIVEHIKVTKSQYSGPRGFHFY
TLNLEKSVSFILERTNLIPEATDDDSEALEAELLPPISHLTVNGSHKRSSRRHSSVGSDP
HNRIIITAAQASNPSYEATALEAGIPAEAVNSRANTLAISEGEGSLGREATWDDFPNGRW
GDARSPAYGEIDGYGVSLHMSINQAIKLWGHPASTSDITNLFLRHIEGQLTAIPWSEEGL
NEETNSIKKQLLGLNKKGWWTVASQPAVNGVRSSDPIFGWGPKNGFVFQKAFVELFIPAS
DWKTLHSKLTSLELCDTVSFYASNAKGDFVSSDQGGAGSTNAVTWGAFPGKEIITPTIIE
EVSFRAWSEEAFGIWGEWARVYGAKSETRKVIEGIMDDVWLVNVIHHAYVEKEGLWDLLL
N
>A0A5N7Z7P2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp|TrEMBL
MKVTQHIANAKGKSLFSFEILPPLKGQNIQCIFDNIEPLMEFKPPFIDVTYHREEYEYKE
LPNGLLEKKIVKKRPGTVGICSAIQNKYQVDAIPHILCGGFNREDTENFLIDMDFLGIDN
VVALRGDAVKSEIYFKPEKEGNQYASELVTQINNLNNG
>A0A2N1J5H1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Malaciobacter halophilus|TrEMBL
MFETLIQKLQEDKYLTLETTPQHEPIMHNIIEKVKKFDLQNRVDGFSATDNPLAKLKYNA
LFASLRLQQEFNKPVIATMSMRDRNKIALQSDLLGANEFDVRAILALTGDPAKMSDQPHS
KGVFESNSSMLLKMIKSFNYGMDIAGRPFKIEPKQIYPFAVTNSYARSFTSLQKKMHTKI
QNGAMGIITQPVFDVNNAKKLLEIFENAKEDVVGNKKKAQLIFGIFPITKLRTALFLSAQ
VPGIHVPQNWVDKLELANQISEEEEYKVGMQLSKELFYNIKKLHPKIHLMTANKFDLADE
ILS
>A0A0P7CJL6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Frankia sp. R43|TrEMBL
MTAVGNAARTTARTVAECLASGRTSFSFEFFPPKTAEGERQLWTALREVEALQPSFVSVT
YGAGGSTRDGTIRVTERIATETNLTPIGHLTAVNHSVAELRQVIGGYAGAGVRNVLALRG
DPPGDPQAEWVRHPDGVAYAEDLVRLVRSLGDFCVGVAAFPDKHPRSPDLETDARFLVQK
LDAGADFAITQFFFGADDYFRLVERVRRLGCDAPIIPGVMPVTNVAQIVRMAQLSGAEFP
ADLAARLQAVADDPAAVRAIGIEVATELSERLLAGGAPGIHFITLNRSGATREIYQALNG
>A0A7V5DSM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLEESLKNKRFVVTSEIQPPIGTGVQELSRNIEKIRGRIDALTVPELKIEGLVTDTLGT
CRVLKEQKFEPILQTTCREKSRIDIQEHLIRAAETGIENILAFTEDYRITGDSLQEIMFF
HVDSGKLFSVLESLQEGHDISGKEIPFKPKFCIGSGIDSSWGKKVPDLELKEMEELAKLG
TRYFLTTPVFDLDSFNQFMKRIEPMRIPVIAEIILVRSAEMGLFLNKHVKPGMVPNHIIE
KLAKAPDKEKASIEIVSNLVKGLKDLCQGVHFIPIGAEDRISKYLDALKL
>A0A7C8EG11|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSDKNVIKSGSNLERVLCSGHFAVTCECGPPRGADVEHLQKKIDLIKGCIDAANVTDNQT
AVVRMSSIAASSILLHNGVEPVMQMVTRDRNRIAAQSDVFGAYALGIRNMLCLTGDHQTF
GNHPMAKNVFDLDSIQLLGVVRTIRDEGTVNSGDPVEGSARMFLGAAANPFADPFEFRVI
RLAKKIRAGADFIQTQCIYDMGRFREFMRMACDMGLDKQCFILAGLTPLKSAGMAAYMNR
NVSGITIPDEIINRMRGVPKGNQAEEGIRLLLDQIQQVRRIPGVAGVHIMAIEWEERIKE
ITERAGLLPRPQL
>A0A7V8Z1Y7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MRVTEHYEKSVEPLISYEIIPPRRGGSIDGILDIVEALLPFDPPFIDVTSHAAEAYYEEM
PGNVVRRHVKRKRPGTIGLCAAIQYRYGIDAVPHILCQGYTREETEDALIELHYLGIRNV
LAVRGDDIGHVKPQRPDRSANVYASDLVAQIVRMNEGQYLEELVDARPTDFCIGVGGYPE
KHVEAPNLGWDIANLKRKVDAGADYIVTQMFFDNRHFFRFVKLCREAGITVPIVPGLKIL
ATTSHLQSLPRTFGAEIPEALADEVRGVDSNAKAADVGVAWAREQSTELLEAGVPGLHFY
IMSSANHVVRVIEPLR
>A0A7C2ZPR1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MEFRERLNTGGFLKLVEVLPPKGVGAEQFEKRLVPVKGKVDAVYIPSLQGGIMRVESWAA
AKYLQDRGYETIFEVCCAHKNRVALQAEVLGGAFLGLRNVMVVAGDDPKLGDHPEAKAVF
DVDVMGLLEGIRGLKKGYDMAGSDLEGAPDLCVGAKVDASAQGPLLELELRDMERKIRLG
VEFFITTTVYDLEQLQRFMERAKEFKVPVIAGLMILKSAGMARYINKHVEGVLIPEGVIE
RLLKAPDKVEESARIAAEMIQGMREICQGVNLIPIGWEEKVPLVLEEAGL
>A0A836NIR2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium longum subsp. longum 72B|TrEMBL
MHSPMFTLEVFPPKRNAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIAHTIS
KEYGIPAVAHLTALYSDKAKIDEALDMFEEAGVSAVLALRGDYIDGEQLVGEFNHASDLV
SYIRSVKPDFKVFGACYPEGHYQADSLDQDIENLKIKVDAGVTHLISQLFYDNEDFYRFL
DKARAAGITVPIEAGIMPVRGAKSVRRMAERNASRIPDKLNTLLNKWGDDIQSLRAAGIL
YASEQIADLVAHDVDGVHLYSMNHPATTRRIWRNAEPLFRGTQG
>A0A7W1Z929|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acidimicrobiia bacterium|TrEMBL
MSSLFRRRSTDATVAARPRPAPAADAALVRLLAATRFELVPIRSVDTAITELPAGIATSV
TCSPVKGLGATLDVTARLLDTGHDAVPHVAARLIEDRQHVARLAAWIRSHGLREIFVVGG
DQLVPSGPYADGLALLRDLFEHDTCLASVGVAAYPDGHPAIPDDVLRTALHDKQRLIEAA
GLAGWATTQMCFDPDRIRRWLLAERAAGFALPVDVGVPGVVDRTKLMSMGVRLGIGSSLR
FLRKQRATMTAMLAPGGYDPTDLATAIAANASALRIEGVHSFTFNSVARTEVWRRSIIDR
A
>A0A8H4BM80|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mucor circinelloides f. lusitanicus|TrEMBL
MKIIDKIEQAQKSNHIAYSFEYFPPKTELGFANLIDRLGRMAQLEPEFISCTWGAGGSTH
DRTLELCTTAQSLYGLDTLMHLTCTNMEKAKIDEALEQAKKAGIRNILALRGDPPRGHEY
WTPVDSEFQHAIDLVKYIRKHYGDTFCIGVAGYPEGHIDCPDKEQDMQYLKEKVDAGADF
VMTQLFYDVDACVTWMQKCRAHGIQVPIVPGIMPIPTYQSFRRMINLCNVKVPDNVMSDL
DAIKGDDQKVKEYGVNLAVNMIQKLHKEAGICNFHISTLNLERSTRLILEALHLHKENGL
HVNKVSPWAPIHDPAKAELWDEFPNGRYGDSRSPAYGENTYSSGQILPTSQAILKWGEPE
TEQDIAQLFINYINGQVKSLPWCEEALHTESETIRQRLTDINQRGYWTVSSQPAVNGASS
QDKIYGWGPKNGYVYQKAFIEFFVSDQQVAELLTRIGKDDSITYYATNRKGDFSTNVSDA
EAQNAVTWGVFPGKEIIQPTIIEKASFEAWKDEAFSLWTEWEEQYAPSSSSQKILKEIGD
RYWLVNVVHNDFQKPDLLFDVMLS
>A0A559K9C5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. JC52|TrEMBL
MLPDLRDALRRQVLVGDGAMGTFLYQMGFPVGISYEELNLLKPDVIESVHRRYFDAGARL
IETNTFSANREKLSKYGLEHEVEAINRAGVALARKAVGYDAYVVGAIGSIRAGRRKNIRT
AKVKEDLRQQIEVLLDTPVDGLLLESFYDLEEMLIALKLIRKTSSLPVICQFATEGAGTT
QDGTALPEAFRMLVDSGADVVGFNCRSGPNGLLRSLEKVAGMEGAPAFSIFPNAGIPDYV
DGRYTYAATPQYFGETARKFADLGAKIVGGCCGTTPEHIAAIAKSLERYIPNPQAISPVS
TGVLESVTAPAVPDLKASVQPSVVDLAKERHTVIVELDPPRDLDIAKFLEGAQALKDAGV
DALTMADNSLAVTRMSNLALGSLVKEKVGIRPLIHIACRDRNSIGTQSHMMGLHALDIDH
VLAVTGDPARFGDLPGSSSVYDMTSFEMIRMIKQLNDGVAFSGKPLKKKANFIVGAAFNP
NVKYLDKAVQRLERKIEAGADYIMTQPVYNTELIEKIHEATKHLNVPIFLGIMPLASGNN
AEYLHNEVPGIQLSDEVRQRMSGLKGEEGRAMGVAIAKELLDAAMRYFNGIYLMTPFLAY
EMTVQLTNYVWEKTGRQDSHLYPLSK
>A0A7V7DEY3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNTKTPSKLEKILAAGHMAVTSECGPPRGSNPEAITKKAEMIRNHVDAINITDNQTSVTR
LCSLAACIRLKLMGVEPVLQMVTRDRNRIALQSDILGAASFDIHNILCLTGDHQSFGDCP
QGQNVHDLDSIQLIQTVRHMRDEGKFIGGDDIQRPPSMFVGAAANPFADPFHIRALRLAK
KVNAGVEFIQTQCIYNLDRFEKWMEMVRDLGLTEKVFILAGLTPFKSAGMAKYMKNRVPG
MDVPDEVVSRMAETPKEKQAEEGINICVESIERLKELPGVAGFHIMAIEWEEKVPEIVER
TGLYPRPQVS
>A0A6I8QQB3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Xenopus tropicalis|TrEMBL
MVNANSSDSGTASCSSAEDSKESSRCSTPVLDVERHERLKDKMRRRVEAGDRWFSLEFFP
PRTASGAVNLISRFDRMGSGGPLFIDVTWHPAGDPGSDKETSSMVIASAAVNFCGLETIL
HMTCCNQTKEDITKHLHKAKHLGLKNIMALRGDPTGEEWEEEAEGFNYAVDLVTHIRHEF
DDYFDICVAGYPRGHPEAEGYDQDLKHLKEKVDAGADFIITQLFFRAETFLTFINDCRAI
GITCPILPGIFPIQGYGSLRQLVKLSKLEVPQEIMDVIEPIKDNDAAIRNYGIDLAVSMC
RELLDSGLVHGLHFYTLNREVATIDVLKRLGMWKEDPRRPLPWAVSAHPKRRVEDVRPIF
WASRPKSYIHRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGQELS
SEESVFEVFTYYISGEPNPNGHKVTCLPWNDDPLAPETNLLKSELQKVNKRGILTINSQP
NVNGKPSTDPIVGWGPSRGYVFQKAYLEFFTSSEMVTALIKVLKRYEPRVNYHIVNVHGQ
NITNAADLQPSAVTWGIFPGREIIQPTVVDPVSFMYWKVGFLYCPHLLLAPG
>A0A318CQE3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKDNFAEHLKEKVVLGDGAFGTYLFEKGVDLAKNTDLLNISDPDLVYSIHEEYIRAGSEL
IETNTFGANRFKMLKVGREHRVREINLRGAELACRAAGDEIFVAGSIGPTGVKFPLESDE
TESGTVQKAFVEQMTALLEGGVDLFIIETFTYLDELLLAIEAAKKIAPDIPVVAQMVYPF
NGRTAIGLDALACGRATAAAGATVVGTNCGRGVKAMLSAVERLSSLKDEVFLSAFPNAGL
PEVVEHRMVYSTPPSYMAEKVTEMVKLGVRLIGGCCGTTPDHIREFRKHLRLKRHKAVSV
AAAVEKSSDLPEDRKDSIGRGGMIESLRPGRIPVLVEVDPPRHLDIEGILTGARALVEAG
ADAITLAEHPLAVLRADNLSLAHRIREETGIQTVLHLTCRDRNALGLQAQIMGAHILGLE
AILAVTGDPATSTDQPGVSGVFDVRSFGLVQMISRFNRGLNMAGASMKKRTNFSIGVAFS
YHPANPDLQISRLERKVDLGAHFAMTQPIFDRDVVESMMEQTQHLDLLIFTGIFPLISAR
NADFLHNEIPGISIPTEVRKHLWKYEKVEDQRKAALDLTRKLIADITPFADGLYLISPLN
KWEIPLTLVKEVRASGH
>A0A7C5BC96|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEFKTNSRLERVLKSGYFAVTGECGPPRGADPEAIRKKGELLKGCVDAVNVTDCQTAVV
RMSSLASCLILKEMGFDPILQMVTRDRNRIAIQSDILGAAALGINNLLCLTGDHQKAGDH
PQAKNVFDLDSIQMVAMVKRMRDEGKFLNGEDLTVRPRLFIGAAENPFADPFEIRTLRLA
KKVAAGADFIQTQCIFNIPKFKEWMKMVVDMGLHEKVFILAGITPLKSVGMARYMKNMVP
GMDVPDELIERLKGVPKEKQGEEGVKIAIEMIQEIREIPGVHGVHLMAIEWEEKVREIVE
GAGLLPRPQV
>A0A7V3H7K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MFETFIQNLQSNAPFITVEVNPPHGASLDPVIEKIKASNLVDKISGFSCTDNPLAKLKMS
GVLSAIKVQQTFHKPVIATMSMRDKNKLSLQSSLLGANDFDLRAVLALTGDPAKFSDQPE
VKGVLERDSTLLLSIIYHLNKGVDYSNKPLDPVPKPIYPFAVSNAYAKDMRNLQKRIVKK
LDYGARAIFTQPVYDPENAKELLELYEEAKTLSVRDTAKDAQLVLGQFPIVRAKTANFID
DKVPGISVPKTIIDEMNLAQMDGEEKEQEVGFALSKRIFDEIMRVHGKVHLMTHNRFDLC
SELIGSIVFKEPYTPTNKKTQTRTHQSGHRSGTEDRWAAHRPA
>A0A1H4JDE6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paenibacillus sp. GP183|TrEMBL
MKMDLRAALKQTILTGDGAMGTYLYQMGFPVSISFEELNLIHAETVEGVHRRYFEAGARL
IETNTFSANREKLSKYGLEGEVEAINRAGVALARKAVGEEAYVVGAIGSIRAGKRKNVRT
SEVESALTEQIGFLLDSPVDGLLLETFYDLEELQLALKIIRSLSQLPVICQFATEGTGVT
QDGVPLQDAFARLAQDGADVIGFNCRVGPNGILRTMEKLTPLPDVPFSVFPNAGLPDYVD
GHYSYAATPAYFAESALRFADLGARIIGGCCGTTPEHIAAIAQALSGYVPAATPLAGAAS
PEAHEPVVVRTPMEAAPAASAASPSLLDLVGQRKVVIVELDPPRDLDIDKFMQGSKALQE
AHVDAITMADNSLAVTRMSNLALGHLVKEKLGARPLIHIACRDRNMIGTQSHLMGLHALG
IDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNDGIAFSGKPLKKKASFVVGAA
FNPNVKHLDKAVQRLERKIQAGADYIMTQPVYDPKRIEQIYETTKHLNIPMFIGVMPLAS
GRNAEYLHNEVPGIQLSDEVRARMDGLDGEAGRKMGLEIAKELIDTIMVYFNGIYLMTPF
LLYEMSVQLTNYVWEKSNRIDFHLYPLSK
>A0A7C3K1Z0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MGLLEENLKKKRFVVTSEIQPPIGTGVQELVRNVERIRGRVDALTVPELKIEGLVTDTMG
TCRVLKDQKFDPILQTTTREKNRIDIQEHLLKASEFGIENILAFTEDYRITGDSLQEIMF
FHVDSGKLFSVIENLHEGRDISGKEISIKPNFCVGSGIDSSWGKKVPDMELKEMEELVHL
GTRYFLTTPVFDLDLFKQFMAKVSPMRIPVIAEVILVRSAEMGLFLNKHVKPNLVPNHII
EKLAKAPDKEKASIEIISDLVKGLKDLCQGVHFIPIGAEDRISKYLDALKL
>A0A2E5PZ00|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSDKIPNWSLEILPHHVSEVQGLPQWVEEIYVTMIPGSKISEVVEASAQLVDEGRTPIPH
IAARGMESREQFSEMLESLKQKGVNRLLLIGGGEEEQQGPFTEVMDLMETGELQRIGFEE
IGIAGHPEGNPSDPDAENSLLKKTRWATKQGISTRIVTQWCFESQTVNRWINNLREQGVT
NPIHIGIPGPATLKTLLRYAQVCGVKASSEVLKKQGFNLGKLLFVNKPDRLVQEIRGHQQ
LHLFPFGGLTKSSEWLQQQRNLASTA
>A0A534V685|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKLADLYARPGLTLSVEFFPPKTEKGEENLFSEIEIIRRLNPSFCSVTYGAGGSTREKTV
DLVETIHNGCGLEVMCHLTVVGQSKAEARGILARLKEKGIENLIALGGDPPQGMADWRPH
PDGFHHAVELVREARAVGTFSIAVAGFPEVHPRAVSRESDLQFLKEKVDAGAAAVITQLF
FDNDDYYRFVDDVRKLGITVPIVPGVLPILSASQIRRFTELCCAKIPAKLERELAKVEGD
DDAAVQMGIDYASHQCEALIKYGVPGLHFYSLNKSYSLSAICKNLGL
>A0A661HN84|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Epsilonproteobacteria bacterium|TrEMBL
MFEKFCDVLCLEKTFITVEINPPHGASISSIIADIKKHKLQDKVTGFSCTDNPLAKLKMS
GVLSAIKVQQEFGKPVIATMSMRDKNKLSLQSTLLGANDFDLRCILALTGDPAKFSDQPD
VKGVLERDSTLLLSIIHHLNKGVDYSNKALNPAPKPIYPFAVTNSSAKDMKSLQKRMVKK
LNYGARAIITQPVYDIENAKELLALFEEAKTLSIRETAKEAHLILGQFPIVRAKTANFID
DKVPGICVPKDIIDEMNLAAMDTEEKEQEVGFRLSKRIFDDIMSLHGKVHLMTHNRFDLC
SELIG
>A0A3N5ZPZ2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
QNVHDLDSMQLIQTVRRMRDEGKFIGGDEIKRPPNMFVGAAANPFADPFEIRVSRLAKKV
AAGAEFIQTQCIYNLDKFEKWMEGVQDRGLHEKVHILAGVTPFKSAGMARYMKNKVPGMD
VPDEVVKRMSDTPKDKQAEEGINICVESIQRLKEIKGVHGFHVMAIEWEEKVPEIVQRAG
LFPRPEVKSV
>A0A1M6LBC6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Paraburkholderia terricola|TrEMBL
MNPIELSFEFFPPKTQEGVDKLRATRTQLALLKPKFVSVTFGAGGSTQQGTLDTVVDMAK
EGLEAAPHLSCIGSSKESLRAILNEYRAHGIRHIVALRGDLPSGMGAVGELRYASELVSF
IRAEFGDWFWIEVAGYPEYHPQSRSPDHDLANFARKVKAGANSAITQYFFNADAYFRFVD
DARKLGVDVPIVPGIMPITNFSQLMRFSEMCGAEVPRWVARRLESFGDDREAIRAFGLDV
VTDLCRRLIDAKVPGLHFYTLNGAAATKAICERLGV
>A0A1V3Q7B9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodanobacter sp. C03|TrEMBL
MPAISFEFFPPKTDEQRAQLDRAAQVLKAYQPEYASVTFGAGGSTLSYTGETVARLHAQH
GFNVAPHLSCVGGTRAELAALLDEYRAAGYRRIVALRGDMPSGMATAGDFRYAAELVGFI
REHCGDHFHIEVAAYPETHPQADDALRDLQHFKAKVDAGANGAITQYFFNPDAYFRFVDD
VRKLGVNVPIVPGIMPIANYSQLKRFSDMCGAEIPRWIAKRMQAHGDDAESVRALGAEVV
AQLCRRLLDGGAPGLHFYTLNRAKATQSVLQQLA
>A0A268U2K3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Helicobacter sp. 13S00477-4|TrEMBL
MIEECINKILHTDFLSYEITPPRESYIQEELILALKDFKEFDALVCTDSPLAKFRPSAIL
TSLKLQNNTKKPVICTLNMRDRNTIALQGDILALNELNIRMFLALSGDPIKLGDHPEAKS
VFEGNSSLLIKIIQHFNQNKDICGHTIKGKIKSIYPFGVINSYANNFLSLKNKMRKKINS
GVIALFTQPVYDIKNAQYLLQACEEINQELHTNAKLVFGYFPILKYKTAQFLYSKLPGVF
VPQDWLEKLEKATKKSEEEEQKIGFELSKNLFTELKNLHNKIHFMNSNNIALAKKIIL
>A0A661M8K5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSEFKSGSNLEKVLKAGHFAFTGECGPPQGANLEALKEKARHLKGCVDAVNVTDNQTAVV
RMSSWAASLVLIQEGLEPNYQMVCRDRNRLAMQSDILGAYAHGIRNMLCLSGDHQKFGNH
PESKNVFDIDSMQLIHMVKEMRDQGVFLNGQEIDEAPRMFIGAASNPFADPFEFRVHRLA
KKVAAGADFIQTQCIYNMPKFREFMKQAVDMGLTEKCYLLAGVTPMKSVGMARYMATQVP
GMDVPDELIKRLKGAGKGKVAEEGIKFALEQIEEFREMEGVAGVHLMAIEWEHRVPEIAE
RAGMLPRPQI
>A0A2D7NN87|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MNNNNTFKWSLEILPRHVGEVHQLPQWVEEIYVTMIPGSDISEVIQASADLVEQGRTPIP
HIAARGLESAEEFSSMLESLKQKGVRHLLLIGGGVEDQEGPFTEVMDLMQTGELQRVGFE
EIGIAGHPEGNPSDPDAENSLLRKTKWAEELGIPTRIVTQWSFDSQVVNEWIGRLRDQGV
NNPIHIGIPGPATLKTLIRYAQVCGVRASTEVLKKQGFNLGKLLFVNKPDRMVREIQGHQ
QLHLFPFGGLGKASEWLEQQQNLASAA
>A0A3R8VLH9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pseudomonas xanthomarina|TrEMBL
MTALNRPSISFEFFPTKTEAGHEKLLNVARQLAGYQPDFFSCTYGAGGSTRDRTLNTVLQ
LDGEVKVPTAPHLSCVGDSKAELRELLNLYKDAGIKRIVALRGDLPSGMGMASGELRYAN
ELVEFIRSETGDHFHIEIAAYPEMHPQARNFEDDLANFVRKARAGADSAITQYFFNADCY
FYFVERVRRLGVETPVVPGIMPITNYSKLARFSDACGAEIPRWVRKQLESYGDDMQSIQA
FGDQVITEMCEKLLAGGAPGLHFYTLNQAEPSLAIWNNLGLSR
>A0A661KMH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MALKEALESGKFTITTEVGPLKGTDTSEILEVAELLDGKVDGVNVTDQQSAVMRLGSLAT
CSLLVEKGLDPIFQMTCRDRNRIALQSDLLNAHVFGIKNVLAITGDFPTLGDHPDAADVY
DLDSVQLVWTIRRMNEGYDLAGNELQGKTDFFVGAVVTPLTDTEAAFELQLIKMEKKIEA
GARFFQTQAVYDVDAFEKFMKRAEEFDVPVLAGIIPLKSVGMARYMNKNVAGVFVPEHLI
DEMAKAEDKTTKGLEIAARLINDLKDLCQGVHIMAIGWEKKVPQILQLANLT
>A0A3D5WG65|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MVSSFKKALESGKFVVTSEVAPPKGTNLEKMVHHIELLKDKVDAINITDHQSSVMRFPSL
GGALLIKEMGGEPILQMTCRDRNRLALQADLLFASSRGIHNVLCLTGDSVLLGDHKEAKS
VFDLDSSQLLAAIRRLERGKDLAGNDLDGGISFCAGAIVTPEANPLEPQLIKFEKKIEAG
AEFIQTQAVYDLDRFKQFMDYARQFPAKILAGIILLTSAPMARFMNKNVAGVNVPQEPID
EMASAPKGRAIEKGIEIAGRMIMRIQEERMCDGVHIMAIGREELVPDIMAAARLV
>A0A2N2GX57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium HGW-Deltaproteobacteria-21|TrEMBL
MDFQKCLSTGEFVILAQMNTPKGVNVSEMVNNARRIKGRIHAVVIPDMDNGVMRMSALAG
GAIMRQQGLEPIIHVYARDRNRMALQGDLLAAHVLGVQALVVVRGEDMSQGDHVNAKCVD
DLDEISLFGAISCLQNGVDIAGSELNGNPSFTVGCTIRPCVDEKSLDSEIEAARKMVEAG
ARFILCPPVFDVDRFSSFVEKTKGLGAVLIPTVFLLKTVGIARYMATYEPGTFIPEHLIK
RMRQAKNREMEGFVIAGETIKHLKSLAGGVQIVTLGWEHRLSTILDYAEV
>A0A661L8F5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MKTKTPSKLEKILSQGHLAVTSECGPPRGSDPAVIVKKAKLIKDHVDAINVTDNQTAMTR
LCSLASVIHLKLMGLEPILQMVVRDRNRIALQSDILGAASFDIHNILCLSGDHQSFGDCP
EAQNVYDIDSMQLISMVRHMRDKGKFVGGDEIDRPPQMFVGAAANPFADPFEIRVPRLAK
KIEAGAEFIQTQCIYNVDKFEEWMRLVRDRGLHEKVYILAGVTPMKSVGMAKYMKNRVPG
MDVPDEIIKRMGSVSKKNQPEEGIKICVETIQRLKEVEGVRGFHIMAIEWEERVPEIVER
SGLFPRPNIS
>A0A259LK03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Hyphomonas sp. 34-62-18|TrEMBL
MTRPANNSQSAVNPVRVSFEFFPPKTEAMNARLWETIQRLEPMAPAFVSVTYGAGGSTRE
RTHDTVRRIVAETTLRPAAHLTCVSATKEEVLAVAEEYWQAGVRHIVALRGDPPAGMGAK
FEAHPGGFTDSVDLIRGLRAHRPELGKCFEISVSCYPELHPESRGWDAEIAFLKAKQDAG
ADRAITQFFFEPDVYLSFLEKARAGGVTMPIVPGIMLQPNFNGLKRIAGLCGASIPGWL
>A0A1A9RH51|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Eikenella corrodens|TrEMBL
MLHNTLSFEFFPTRTPEGREKQKITRKQLSQYQPEFFSCTSGAGGTTREGTMQTIRDILA
EGMAAAPHIPCVGLDAGELTDLLQEYKDLGIRHVVALRGDIPSGMGLGTTGLHHANELVE
LIRHRFGDWFHIEVAAYPEYHPQSRSAEDDIQSFVRKVKAGADSAITQFFFNADSYFRFL
DDVRGRGVEIPIVPGIMPIANFSKLARFADMCGAEIPRWLRLKLQSYADDTASIKALGLD
VVTEMCGRLLRHGAPGLHFYTLNQAGLSSTICQRLGY
>A0A496YVK9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Deltaproteobacteria bacterium|TrEMBL
MSELKSGSNLEKVLKAGHFAFTGECGPPKGANVEHLREKLSHLKGKVDAVNITDNQTAVV
RMSSWAACAILIQEGLEPNFQMVCRDRNRLAIQSDILGAYALGVRNMLCLSGDHQTFGNH
PQAKNVYDIDSMQLISLVKKMRDEQKFMNDEEIDVAPKLFIGAASNPFAEPFEFRVYRLA
MKIDSGADFIQTQCIYNMQRFRGFMKRAVDMGLHERCYILAGITPMKSVGMAQYMAKAVP
GMDVPESLIKRLRGAGKGKVAEEGIKFAVEQIQELKEMEGVAGVHLMAIEWEHRVPEIAE
RAGMLPRPKV
>A0A2P5VMW6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Alphaproteobacteria bacterium MarineAlpha1_Bin1|TrEMBL
MKYPQTSGRLAGVLGQGGFAITSETTPPLTADPSVVVKRTAPLAGLVHAVNVTDGAGARA
HLSSFAAAHFMQAEHGLEGVMQFTTRDRNKLALERELLGVAGFAIPNVLCLSGDPLSKGD
EPEATAVNDVDSAGLVAIATQMREEGLLPSGREIKPPPQYFIGVADTPIDPADDWRPTSL
MTKIEAGADFAQTQFCFDTEILGRYVARLQDFNIPVRLPLLIGLAPLSSARQARFMRENL
FGTIIPDALITRLECADDPRAEGRRICVELIEEMQGMPGIAGVHLMGHQAEEQIAETLRD
GGFAI
>A0A037ZKB8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actibacterium mucosum KCTC 23349|TrEMBL
MSAPTISFEFFPPQSLEASFRLWDTVQALAPLKPKFSSVTYGAGGTTRKLTHDAVTTIHK
NYGLNVAAHLTCVNASRDETLEIANAYAEVGVTEIVALRGDPPKGQGSFTPHPDGFANSA
ELVAALAETGKFTLHVGAYPEPHPDAKAAGDDVAWLKRKVDAGANSAITQFFFEADTFFR
FRDACVAAGIDVPILPGILPIEKWKGARNFALRCGTQVPAWLDAAYEKAIAEGREAALGQ
ELAIKLCDDLLRGGVDHLHFYTLNKPHLTMAVCDSLGITSDVASENTPELA
>E4V9M9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bifidobacterium bifidum NCIMB 41171|TrEMBL
MHTPMFSLEVFPPKRDAPVGTIYDTLDGLEGLNPDFISVTYGHGTHSDRTATARIANTIH
GEYGIPAVAHLTALYSDEAKIDEALDMFEAAGVSAVLALRGDYIDGEEPVGRFNHASDLA
AYIHDRKPDLKVFGACYPEGHYSAASLDEDIGNLKIKVDAGVTHLISQLFYDNDDFYRFL
DKAHAAGIDVPIEAGIMPVRGAKSVRRMAKVNASRIPAKLEALLDRWGDDIQNLRAAGII
YASDQIADLVAHGVDGVHLYSMNHPATTRRIWHNVEPLFTVE
>A0A644T990|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|bioreactor metagenome|TrEMBL
MFKTLIQKLQEDKYLTLETTPQHEPSMHNIIEKIKKFNLQDKIDGFSCTDNPLAKLRYNS
LFAALKLQQEFEKPVIATMTMRDRNKIALQSDLLGANDFDVRAILALTGDPAKMSDQPNS
KGVFEANSLMLLKMIKSFNYGMDFAGHPFKIEPKQIFPFAVVNSYAKNFSSLEKKMHLKI
QNGAIGIITQPIFDIENAQKLLESFDIAKENVEGDKRKSQLIFGIFPVTKLRTALFLSAQ
VPGIHVPQFWIDALEKAHSIGEEEEYKVGMELSSNLFKELNKLHPKIHLMTANRFDVANE
IIS
>A0A838R6C4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gemmatimonadales bacterium|TrEMBL
RGLDPGGNPIGEPTRFVVGVGVNPAAPDLDRELKRFAWKVEAGAEWAITQPVFDLPQLDR
FLERTQSLRVPIVAGIWPLVSLRNAEFLANEVPGVSVPDSVLDRMRRASAGGKEEALAEG
VRISQEMLAAVAERVQGVQVSAPLGRVSVALEVLSAAPIEPAVTHGYTPGT
>A0A8I1PSZ5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Nitrosospira sp|TrEMBL
MESQKKFAPTFSFEFFPPQTPEGMEKLRATRRQLAQLDPKFFSVTFGAGGSTRDRTLETV
LEIQAEGHVVAPHLSCIGSTGESIRSMLQKYYDAGIRHIVALRGDLPSGMAQAGEFRYAN
ELVTFIHQEFGDTFHIEVAAYPEYHPQAVSPGEDLRNFKRKVDAGADSVITQYFYNADAY
FNFIDSCEAIGVDVPIVPGIMPINKFSQLARFSDACGAEVPRWIRKRLEGYGDDSASIRA
FGLDIVTELCDRLLRAGAPGLHFYTLNSAGLTATIWQRLGL
>A0A4Y8M766|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Cohnella luojiensis|TrEMBL
MKPDLRTALALKPRVGDGAMATYLYQLGLPVGVSFEEFNLLKPDVIADVHRRYAAAGAEI
IETNTYSAQHNKLSKYGLEKKTEEINAAGVSIARRAVGQEAYVVGSIGAVRGGAGKNVRT
AVVKRDFEEQIGVLLASGVDGLLLETFFDLEELSLALSIIRKKSDISVICQFAVEDAHRT
HDGIPLPEAFRRLKGEGADVIGFNCRSGPNGILRALETIPRDLGVSLSVFPNAGIPDYVD
GKVVYSATPEYFASSAIKFADAGARLIGGCCGTTPEHISAMAQALQGYSPNAHAAAPEGA
TPAQPVEVIEASFQSGKPPLVTEPSIIDLVRERHTVIVELDPPRDLDISKFMAGAQALKD
AKADALTMADNSLAVTRMSNMALAALLKERVGIRPLVHIACRDRNLIGTQSHMMGFDALG
IDHVLAVTGDPAKFGDLPGSSSVYDLTSFEIIRMIKQLNEGIAFSGKPLKQKANFIVGAA
FNPNVKHLDKAIQRLERKISAGADYIMTQPVYDPDLIERIAEMTKHLTIPIFLGIFPLAS
GRNAEYLHNEVPGIQLSDSVRQRMSGLEGAEGRAEGVKIAKELLDVAMARFNGIYLMTPF
LAYEMTVSLTEYVRKKSKSLTSDK
>A0A7K1YZ27|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermaceae bacterium|TrEMBL
MLQWAEAAGFSVQVKKFDPPASLDQGISVLIWTATWHASPPGGYSVNQLAAAEQQSKPAP
DVSFEFFPPKTDKMEAKLWESVARLTPMAPRFVSVTYGAGGTTRNRTQRIVTKIAQDTPL
LPAAHLTCVSATKEEVLQVAVDLWRAGIRHLVALRGDPPEGIGEKFEQHPGGFRNSIELI
EGIRAHDAVPDARFEISVSCYPEQHPHSRGWDQDIAFLRAKQDAGADRAITQFFFEPAIY
LAFLDRARAGGVTMPIVPGIMLQPNFKGMKRIADLCQVNLPDWLHELYEGTDEDTATCEF
ITANVAAELCHKLSEQGVNEFHFYTLNRASLALSTCRLLGLKPQAVV
>A0A8H4TNT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Fusarium gaditjirri|TrEMBL
MDKITDRIAALPADGTYFSLEFFPPKTAMGFSNLRDRLHRMERALRPLFVNVTWGAGGST
SQKSLELAELCQREVGLTTCLHLTCTNMSKKLIDEALSDAKALGIRNILALRGDPPRREE
YRDPEDSEDDGGQDFNWAVDLVRYIRKTHGDYFCIGVAAYPEGHAEESHPLGQSLEHDLP
YLVQKVQAGADFIQTQLFFDIEAYEHFETTLREHPSGAFKGIPIIPGLMPIQSYQMIKRT
TKLSHAKIPGHLLARLDAVKGDDERVKMVGVDIVSELIDKIKDIKSKTPGPKGFHFYTLN
LEKAVSFILERANLIPDPPENEEAIAVDELAIPSLQINGSANMRSSSHSRSRQSRRHSSV
ASDPHNRVIVGDRPAMYPEWEATGQEAGVRAEAINTRANTLAISEGEGVLGREATWDDFP
NGRFGDARSPAYGEIDGYGVSLHMSVTQAVKLWGYPKTRQDINDLFVKHIRGELSAIPWS
EEELRAESSTIQPNLLQLNRKGWWTVASQPAVNGLRSSDGTFGWGPPNGFVFQKSFVEFF
IPANEWDTLKAKLTSPELQDSVCFYASNARGDYLSSDNSDHVNGPTEAGPSTNAVTWGVF
PGKEIITPTIIEEVSFRAWSEEAFGIWGEWAKVYGRGSESEKLLNGIKDDYWLVNVIHHD
FVEKDALWQLLSS
>A0A7K2C7L8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhodothermaceae bacterium|TrEMBL
LAVGELARILDQSQPRLSHHLKSLTKAGLVERLPEGAWVFYRIQRRGWADRLLQGIFSKL
DVDSDPFTTDFNVLQRVRANRAQSAASYFSEIANDWDQLRALHYPDAAIEREILGHVECH
QFERIVDLGTGTGRMLILLAPYTQEAEGLDQSHRMLKVARANLNRAGIGNARVRQGDAMN
TPFESDSADLVIVHQVLHYLEQPERVIAEAARILKQGGQLIVVDFAPHELEFLRESQGHY
RLGISEDDMMRWADSAGFSMQPPRRFNPPSSLDKGLSVLIWKAAWRVYQPADPSVSKLSV
AEQQSKPPPNVSFEFFPPKSDSMEAKLWESVARLTPMAPRFVSVTYGAGGSTRDRTRRIV
TKIAQDTPLLPAAHLTCVGATKEEVLGIAVDLWKAGIRHIVALRGDPPEGIDAKFEQHPG
GFRDSIDLIEGIRNCEITPGARFEISVSCYPEQHPHSRGWDQDIAFLRAKQDAGADRAIT
QFFFEPEVYFKFLDRARAGGVTMPIVPGIMLQPNFKGMKRIADLCQVTLPNWLYEVFEGT
GDDAVTREFITANVAAELCHKLSDQGVNDFHFYTLNRASLALSTCRLLGLKPQAVA
>A0A7D0INS8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Stenotrophomonas maltophilia|TrEMBL
MPAPGSQRAEAFINAFSLEVSAKAMPALRAEADRIAPGTTISIPYLASEDDDARLAAART
VRELGFEPMPHLSARRIASRAALARFLERAASEAGVETCLLIAGDLSAPAGPFADSTSII
ETGLLERCGIKVVAMGGHPEGHPMMNAEDRWRVLERKCQAIEARGMAPLIITQFAFDADI
VLAWLDALRARGITVPVLVGVPGPASIARLARYAAMCGVGASASMLARYGISIGRLLGTA
GPEVFMDRLLSGLTDAHGPVSPHLFPFGGIAPSLEWVEQYRRSIYSSGG
>A0A2N0HE38|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Flavobacterium sp. 5|TrEMBL
MKVTEHIEAAKEKTLFSFEIIPPQKGKSIQELYDNIDPLMEFNPPFIDVTTSREEYIYID
KGNGLLDKKLTRMRPGTLGICASIKHKYNVDTVPHLLCGGFTKEETEYMLVDCHYLGINN
VMALRGDAMKDEQSFVPKLGGNNFAVDLVAQINQLNCGKYLHDVMDADNKADFCIGVAGY
PEKHLESPSLLSDLKRLKEKVDAGADYVVTQMFFDNAKYFEFVKKAREMGITIPIIPGIK
PIAVQKHLQILPQIFRIDLPEDLISAVDKCKNNADIRQVGIEWAIQQSLELKAAGVPVLH
YYSMGKSENIRQIASQVF
>A0A328PQT1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Petrotoga sp. 9PW.55.5.1|TrEMBL
MKIIDFICQSEKPILSFEIIPPQVGESIDSIFKAIDNLIEFSPKFINVTKHADEIEYLEE
NDKIVKIIKKKRPGTVGISASIKHRYNIEVVPHLICTGINKYQLEEILVDLNYLKIDNVL
VLRGDKKKYTWREDGEYDHAYQLVKQISDMNKGIYTTPTKEHNPTNFCIGVAGYPEKHFE
SPNFEKDLEYLKLKVDMGAEFIITQMFFDVEYYLNFVQKVRNFGIEVPIIPGIKPVASKK
SLYNIPQNFHVNIPKNMVEDFDNAVTAQDEFSVGVKHTVDLIAKLLELGVPGIHLFTMGK
GKIIKAVLKEFREVF
>A0A2N3KWP5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Thalassospira marina|TrEMBL
MTPVRDNTQQTASNSRDLRVSFEFFPPKTEKMEETMWRSIHRLAPLAPSFVSVTYGAGGS
TRDRTHASVTRIQRETGIAAAAHLTCVGHTRDEIERIARTYWDEGIRSIVALRGDLPDAG
GKYVPTPGGYDYAVDLVAGLKKIEDFDISVSAYPETHPDAPTADFEIDYLKRKFDAGANR
AITQFFFDNEVFLRFRDKCDKAGITAPIVPGILPVTNFASLLKFADMCGAGVPQRLHHRF
DGLDEDPDTRRMVAFHEAISQVEGLIAEGVNDFHFYTLNRAELTYAICHALGIRAKQVAA
SA
>A0A2S9FEJ9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mycobacterium sp. ITM-2017-0098|TrEMBL
MPFDPADVERVAATLAPSCDAILVGEHQNRPDFPPTLMSRMLLDGGMTPWITLSCRDRNR
IVLEQELRGLSLLGVRTVFCVTGDGRGYDVRPDVTQTFDLDGPRLVALSASLGMTAAVPE
TPTAPPVAARPVRLVQKQRAGASIAVLNHVTAPASVERFVTSAKATGLTIPVLAAVAVFT
DAVSAAVLQGLPGLELDPEVVNRVLAAPNPIEAGIEAAVAEAQALLKIDGVVGVNISGSA
SSGGTRLGAEIKAEVGARIRAAA
>A0A3R9SED1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus oralis|TrEMBL
MSRQTPSLSFEVFPPNPAVGNDKIISALQDMRELTPHFISVTASNNKFNIKETTVRLADF
IQNDLAIPTIAHLPAIYLTKEKVAETLADLDKVGVRKILALRGDIIPDVEPQKDFHYATD
LIEFIKEQAPHFDIVGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYEHDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNAETAKYIHQATHALFNHQSLG
>A0A2T1CIV3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pleurocapsa sp. CCALA 161|TrEMBL
MTNNLRQAVLDKKFLLTAEVAPPKGGNPARMIEVASKLTDRVHAVNVTDGSRAVLRMSAI
AASTILLQHGIEPVCQMACRDRNCIGLQADLMGAYALGIRNVLALTGDPVKAGDHQKSRA
VFELESVRLLKLISKLNSGVDFNDQVMPDDALNLFAGAAVDPQLKSWSSLQKRFEQKLAA
GAQFFQSQMITDFDKLDKFMTQIASISDKPVLAGIFLLKSAKNAKFINKYVPGVDIPEAI
IDRLAKAEKPLEEGVKIAAEQVKLAQDICQGVHLMAVKREDLIPEILNQAGIEPLSIAAI
QA
>A0A2T2SMH7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacteroidetes bacterium QH_1_64_81|TrEMBL
MKVAEHFDQASEPLISYEIIPPKRGGSADQILRVVEELMPFDPPFIDVTSHSAEVEYKQQ
DDGTWQRCVKRKRPGTIGLCAAIEARFGIDTVPHLLCKGFTREETEDALIELNYLGVENV
LAIRGDDKGYEKSISGNRSRNEQAVDLVRQIQDMNQGTYLEDMMNAEPTDFCVGVGGYPE
THFEAPNLAWDIMRLKEKVDAGADYIVTQMFFDNEYFFNFVDKCREVGIDVPIVPGIKIL
KRKRHLRLLPKYFHTEIPEELAAEVDAADPDDVENIGVDWAIRQTRELMEAGVPCMHFYI
MSSADTVKKVVEPLHEMA
>A0A0U1HVK7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Yersinia rohdei|TrEMBL
MSFFHANQREALNQSLAELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTY
GANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPAQLRDIATDYWNSGIRHIVALRGD
LPPDSGKPEMYASDLVTLLKDIGDFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANRA
ITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLKRFATMTNVRVPHWMNTIFE
GLDEDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>A0A1G0G9R4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Gammaproteobacteria bacterium RIFCSPHIGHO2_02_FULL_39_13|TrEMBL
MSSPHLSFEFFPPKTTAGINALLQTAGMLTAINPSYFSVTFGAAGSAQTHTPDTVFKIKK
HTRIQTAPHISCVAAEKENIKNLLDRYIQKDISRLVVLRGDAPANTTIPSTHFQHASELV
QFIREQTGNHFHIDVACYPEFHPQTTDVKRALFHLKEKMDAGANSMITQYFYNPDAYFRF
RDDCEKFHITAPITPGIMPIIHYEKLVSFSNACGAEIPRWLKFRLENYKNDIISLHTFCD
DVLTDLCEKLLSGGASGLHFYTLNKSEYCLNILKNLKINPVFA
>A0A1A0DDZ7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Acetobacter pasteurianus|TrEMBL
MSLSRLSVELIPRSAEALAADVATVKAAFPAADTLNIPDLMRFPLRSWDAAALVRPQFGN
VIPHIRAIDIAPDAPLPGADQPGLEEILVVHGDPPADLSHRTYPNSTESIIRRYRREAPH
LKVYAAFDPYRRAPWKELEDVARKKEAGAIGFFTQPVFDLKLFDLCREWMQGECVFWGLS
PVIGPKSRSYWETTNHIVFPRDFSPTLDANIQFAQTVLKELAQEKGKAYLMPVRIKLEQY
LPALLDAVA
>A0A1X0S8N0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus microsporus|TrEMBL
MQRFGPEFIDITWGAGGSSADLTTEIVATTQSVYGLETMMHLTCTNMPIEKIDKALEAAK
RCGCQNILALRGDPPKGQLNWESCENGFNYAIDLVRYIRDKYGDYFCIAVAGHPEGHVDN
PDKDDDLLRLKQKVDAGADLIVTQLFFDVDIFVDFVKRCRDIGIQCPIIPGLFPIQSYSS
LSRVISFNKNHVPQKIWNDLETVKDDDQAVKDYGIDLAIQFIKRIKQETGISGFHIYTFN
LERSSRLILEKLGLVPEQEYVKPLPWNPSLTPTRGKENVRPIFWKHRTQSYIQRTESWDE
FPNGRWGDARSPAFGEFDRWGVSIKYPPEKQLAMWGTPESVDDIALLFAKYCKGKLEALP
WSAQKLDPETDIIKQRLAAINFLGYLTINSQPAVNGVRSSDPVYGWGPRNGYVYQKAYIE
FFVSPDQLQVLIDKMNHEPEITYFAVNYKGELKTNTIYKEPNAVTWGVFPGKEIIQPTIV
EETAFMAWKDEAFELWSEWARIYDRKSPSAEVILDIHDHWYLVNIVHNDFQDEDGIWRLF
DLEIDGDLSRRLRRGSGSF
>A0A2M7S094|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Elusimicrobia bacterium CG_4_10_14_0_8_um_filter_37_32|TrEMBL
MKLKDLFKSGKFAVTSEIGPPKGCHIDNVLHEAETFLKGRVAAINVTDNQSSVMRFGSLA
TSHLLKDRGMEPVFQVVCRDRNRIALQSDILSAAGLGI
>A0A7Z0IIT0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Spelaeicoccus albus|TrEMBL
MTNADDAISVAELLEDYSLEMTGKDVPGLIEAHESIPPGTRVNVTFLGNEDMPMRVSAAA
AVRSFRLTPVPHISARRLESEAELRKFLDSLVERAAVDSVLVVGGDPATPAGPYADSLAV
IRSGVLAEYGITKVGIGGYPEGHPDIRDEALWQALTDKARAVADVGHEVSVITQFGFDTG
RVIEWVAGVRARGIDATLRIGVPGPAGIRRLLSYAKRFGVASSAGIARKYGFSLTNLLGT
AGPDHFVRDLAAELPPAEREKVRLHFYTFGGLARTADWIAEFGASEP
>A0A3S3QH41|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Electrothrix communis|TrEMBL
PKNSDPDVVREKARILKGNVDAVNITDCQTAIVRMSSIGAGLLAQAEGLEPVIQMTCRDR
NRIGMQSDLLAASALGLKNLLCLTGDHQKFGNHPGAKGVFDMDSIQLLGMIRDMRDGKKF
QCGEEIKGKGTDLFLGAAANPFAYPYEFRAVRMGKKIANGADFIQTQIIYNLDRFTEFMK
TTCELGLHEKAYILAGVTPPKSVGMARYMKKFVPGMDVTDEVIKRMQGAKDKKQEGINIC
VDIINQVKEIPGVAGVHVMAIEWEEAVPEICERAGLLPRPTFDDDAASVPETIVAARETI
EVRTAAGAADDVLEQAKAEAEKIIAAARTEAAALSAQAAQSGEATTENAAASGQAADDAG
EHAMNEKGRREALESVNQGLNALKKAYGLSDDQFDALMNFVDAASVLNKEPEGLTQQPVG
ATPAPAAVSS
>A0A7W6P269|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizobium borbori|TrEMBL
MATPLLSAAEIARLKISFEFFPPKSPEMDGQLWDTVADLGGWEPDFVSVTYGAGGSTREP
TLVTVRKLIAETALRTASHLTCVGSSKDEVHRVVEELKAAGVQRFVALRGDPQEGPGSTY
RAHPEGYANAAELVKGLKALGDFDISVSAYPEKHPESESVAVDIDMLKRKADNGADRALT
QFFFDNDQFERYLTAVRAAGITIPVLPGIMPIQNLTQLKRFAGRCGTSIPAFLDERFAGT
EDDATHRFEVAADVAAEQIADLVRRGVSDFHLYTMNRAPLTNAVLSRLGLARKDAKAA
>A0A847QMQ0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Peptococcaceae bacterium|TrEMBL
MYISELFDQKKAVISFEIFPPKQTSSIVTIYETIDALAPLRPDYISVTYGAGGSTSKTTL
EIASIIKNKYRINALAHLTCFNSSREDIDKMLTDLEKENIANVLALRGDRPRTWKAGEEK
ESDFKYAADLAKFISSKHKFCLGGACYPEGHPECSDLDRDVENLKRKEEAGVDFLITQLF
FDNEKYYRFKEKADKSGIKIPIQAGIMPITNRKQVERMIELSNATIPHKLVRILDKFEHN
QQAIRDAGIAYATEQIIELLANEIRGIHIYTMNKPQIAKDLVRNLDSILYALNN
>A0A822PME2|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Shigella flexneri 2a|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A1E4IB57|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rubrivivax sp. SCN 71-131|TrEMBL
MRVLRHWAVRHARGLRRVYEGFARLAPAFAPALRLLGRRRAEALLHPIEHSAKSLLFDCR
DCGQCVLSATGMACPMNCPKTMRNGPCGGVRPDGGCEVRPDMRCVWLEATEGTKRIDGVD
CARPTPLLPAIDMRRAGRSTWIEVVEGRRDPAFQPPVGERTTPEARQSALERACRSGRFV
VTVEIAPPDSADPAPLLERAAVFAGLVDAMNITDGAGGNCHMSSAAASAVLAANGLEAVY
QIACRDRNRIAIQGDILGAAALGVRNVLCLTGDDVSQGDHPQAKAVFDLDAVSLLHVARG
MCDQGTYASGRKLLTPPDLFVGATANPFVPPFVDRVANLEKKIVAGARFIQTQFCFDVAM
FEEFMREVRRRGLHERAHLIVGVGTLSSAKALAWMAAHVPGVHVPAAVIERIAGAADQRA
ECRQVCLETIRALREVEGVAGIHVMGHRNEELLADVIRTAFPERAPIAAGKCGPAVAETV
ATRPEPLTPSIDRPASLKQRGDGFLDVIAARPAARLGGRCLAQRLRRGNRVGIAQQAQHL
QGLGQHVRRLGQQLFGPGGGHGERGSGRGQSIDQADLMGALRAQAGAAEHLGRDGMRQVL
PQQHEAAEIDLGQAKARLLVGDAQVGAQREIDARADRRAVDRHEAGLVDAAGPVRIPSDG
FEEDSGAVFASLHALEPALVGTGAEDAALAGEDGQPRLVVALVAPPRRGQFGQHRLVDRV
EPVRSVQRDRDQVPLPAVLDRHLSCSTALRATRDA
>A0A3S0JV86|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Halomonas nitroreducens|TrEMBL
MKFDDEPVPGYSLPILPGHVSPGRLERVLRAGRFALTTEIDPPDSADPAEVLRRAAIFDG
YVDAINATDGSGANCHMSSVGVCSLLTRVGYATILQMSCRDRNRIAMQGEILGAAAMGAC
NLLCLTGDGVQAGDHPQARPVFDLDAMSQLEIARRMRDEGRFESGRAITDPPRIFLGAAA
NPFVPPHAWRALRLAKKVAAGARFFQTQYCFDPQRLRDFMAEVADLGVLEGPDRVFVLVG
MGPLASARSARWIREHVPGVHIPDAVIRRLEGARDQRAEGERLCCDILAEVREIEGVSGA
HIMAYRQEHTVARIIEETGVLEGRVPWYPGRDNPAELNPEATEAELPASGTG
>S3AJM9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptococcus sp. HPH0090|TrEMBL
MSGQTPSLSFEVFPPNPAVGNEKIIAALKDMQGLAPHFISVTASNNKFNIKETTVRLADY
IQNDLEIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALRGDIIPDVEPQKDFRYATD
LIEFIKEQAPHFEIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFYD
FQDKCTLAGIDVPIHAGIMPILNRNQALRLLKTCENIHLPRKFKAILDKYENDPESLRAA
GLAYAVDQIVDLVTQDVAGVHLYTMNNADTAQYIHQATHALFNHQS
>A0A2P2CID4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|metagenome|TrEMBL
MTHARGLSMRELLARGDRSFSFEFFPPKDEAGEQQLWQAITELEPYDPTFVSVTYGAGGT
TRDRTVAITARIARETGMLPVAHLTCVGHTTGEIEAILDDLDTAGVRHIMALRGDPPGGP
GTPWTPTDGGLTYASELVALIRRRADMRIGVAAFPEGHVDAADLDQDARVLKAKYDAGAE
FAVTEMVLRASDYVALVERARAVGADLPIIPGIMPILNLRSMERMVELSRRQLPDEVRER
LTPHADDPARLRAEGIAIATELCEALLDAGAPGLHFYTLNRSKATREIFDNLRITV
>A0A2V2PQ69|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Streptomyces sp. ZEA17I|TrEMBL
MALGTASTRTDHARTVRDMLATGKTSYSFEFWAPKTEKGERNLWSALRRIEAVRPSFVSV
TYGAGGSTRAGTVRATQQIAADSTLTPVAHLTAVSHSIAELRNMVGQYADAGIRNILAVR
GDPPGDPMGEWVEHPQGVTYAADLVRLIKEAGDFCVGVAAFPEMHPRSTDWETDIGHFVD
KCRAGADYAITQMFFRPEDYLRMRDRVVAAGCETPIIPEVMPLTSVKQLERFSQLSNATV
PEPLKERILAVKDDPAAVRSIGIEFATEFCAKLLSEGVPGLHFITLNNSTATLEIYENLG
LHRQS
>A0A1E4T4W9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|[Candida] arabinofermentans NRRL YB-2248|TrEMBL
MSIKITDKINALGENEPFFSLEFFPPKTENGLRNIFARLGRMSLLGPSFVTITWGAGGST
AQKTLDLAITCQKELGLTTCLHLTCTNTSKDVIDNALTQAKENGIKNILALRGDPPRDET
NFVNNGEFKYAVDLVKYIRENHGDYFCIGVAGYPEGHVEGSDSSEQNVMFDLPYLAEKVN
AGADFLISQLFYDTDKFLEYEKLVKSYDKIKNKDLLIIPGLMPINGYGIFQRASKLSHAS
IPDEILEKFPEEIQYDDNKVKEIGVTILSDMISKIYKQSEGKVRGFHFYTLNLEKSIAQI
IKSSDVLDQVVTKKEEEEEKIAQSKGDGQQSSDEDIDETTTTAKRAAYANRFRQSSNQLI
VDGPNVKSHKLSHSARTSSSQIKKIISISAGEGALGKDATWDDFPNGRFGDSRSPAYGEI
DGYGPSLKITSTRAYELWGKPKTLDDISNIFIKYLSNKIDCLPWSDLGLNPETAIIQEEL
IGLNELNFFTVSSQPATNCSKSNDNIFGWGPKNGYVYQKAFVEMFISKKSWAEMLKRIES
NEHISYYAADNKGYYDSNLTGQNSNCVTWGVFPDREIVQTTIIEEESFKAWSDEAFNIWK
EWQLLYPKNSDSSKLIQQILDDYLLVSVIHHDYPDEQALWELLLSSKSDDVIYS
>A0A0F0HZS7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1)|TrEMBL
MHIKEKLAQNEAAERVGISFEFFPPKTAQGVQNLYDRMDRMHALGPSFIDITWGAGGRLS
DLTCEMVNVAQSVYGLETCMHLTCTDMPTEKVDAALQAAYKSGCTNILALRGDPPREKEK
WEAAEGGLRYAKDLVKYIRDKYGNHFDIGVGGYPEGADDNPDVDLLIDHLKEKVDAGASF
VITQMFYDTDLFISWVKKCRAKGINVPIIPGIMPIQTYAAFIRRANWTKIHIPEDWLEAL
EPVKNDDAAVKEIGKVLIADMCRRLLAAGINHLHFYTMNLAQATQLVLDELKLMPSEETP
IQRPLPWRPSLGLNRRAEDVRPIFWRNRNSSYIARTQTWDEFPNGRWTDSRSPAFGELDS
YGIGLKGTNEQNIQLWGEPKSIKDLSRLFVRYLEGKLSRLPWSDTPISSEAKAIKPNLIE
LNHRGILTINSQPAVNGARSSHPVYGWGPKNGFVYQKAYLELLIPPYLLDELIARIEGNE
DLTYHAVSKNGELRTNTHDSPNALTWGIFAGREVVQPTIVETISFLAWKDEAYRLGEDWA
KCHAATSPSRKLIQGLVDSWYLVNIVNNDFHNTYDLFELFKDLNVRDFDVEVAADNADLK
SQENETAETAAN
>A0A7Y6XAC5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Myxococcus sp. AM011|TrEMBL
MKIRNRLNPSNPCFSFEFFPPKTDEGVANLLKALEDLAPLEPGFVSVTYGAGGSTRDRTV
ELVTRIKAETGIEAMAHLTCVGHSRQELKELLQRLADAKLDNVLILRGDPPQGQKSFVTA
EGGFTYASELVRFIREEDFNFCLGGACYPEGHVETASRDDDLRHLKAKVDAGLDFVVTQL
FFDNAFYFDFVERARRAGINVPIVPGIMPITNFEQVQRFTRMCGATVPMRLGLQLERVKD
QPDAVVQLGVAHATVQCMELLSRGVPGIHFYTLNKSPATRMIVSALRART
>A0A4U2XT61|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bacillus mycoides|TrEMBL
MKLLDLLSKGIVIGDGAVGTLLHSHGLQSSFEELNLSDPDLIISIHKQYVAAGADVIQTN
TYGANEAKLRMYGLENQVVQINKAAVNIAKASVTDRNAILGTIGGMKHIGAVTTTDIERE
FMLLEQAGALLEEQVDGLLLETFYDEFELLHAVKVLRKQTNIPIVAQLALHEAGTTQNGN
DVNEILKQLLDYGANVVGLNCQLGPLHMTEAFKMISIPQNGYLSAYPNAGLPNYVEGRYV
YEGSPAYFEEMTPKFIEQGIRLLGGCCGTTPEHIEGMKRAIANVAPVIAKETIQRPKVVH
THEKRSRAHVTLAEKGKKQTTVVVELDPPKTLDTQRFFEGARALKRAGADAITLADNSLA
SPRVSNMAMGALLTKHDIPVLTHLTCRDHNVIGLQSHLLGLSALGMEEVLALTGDPARVG
DFPGATSVYDLSSIELIKMIKEMNDGRSILGKSIGPATRFSVGGAFNPHVRHLKAAVKRM
ERKIDAGAEYFLTQPIYDVALIEEVYEATKHLEQPIFIGIMPLVSKRNADFLHFEVPGIT
LPEEIRQRMDGHETKDAAIEEGIRISQELIDAAMKYFNGIYLITPFLKYEITEHLVKYVR
EKQEVKEGIN
>A0A7D5G9H0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MAQGYSVRRITSADFFRLFLSGQAMTFELSIEFFPPQTAEGIEKLRATLAQLAALKPAFF
SVTYGAGGSTRERTLATVREIASAGYSAAPHLSCIGATQESIRELLATFQSQGIRRIVAL
RGDLPSGMADPGEFRYANELVAFIRRETGDTFHLDVAAYPEWHPQARTPRDDLLNFKRKM
DAGANAAITQYFYNIDAFENFINEAHALGITAPIIPGIMPIGSFSKLARFSDACGADIPR
WMRKKFESYGDDTASVQALGLDIVTELCQQLISRGAPGLHFYSMNQSRLTLEICRRLGIG
>A0A8C3NCU8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Geospiza parvula|TrEMBL
MLGLGIGFFNHLLLTPAVPALCRHPCTDCPLCAPLCRAPTMVNETQHSCSASSSSRSDGG
SSSGSESSKDNSRCSTPVLDADRHERLREKMRRRQDAGDKWFSLEFFPPRTANAAVNLIS
RFDHMGAGGPLFIDVTWHPAGDPGSDKETSSMIIAYTAVNYCGLETILHMTCCNQSKDDI
TGHLQKAKRLGLKNIMALRGDPAGEEWEEEVDGFNYAVDLVKHIRNEFDDYFDICVAGYP
KGHPEAESYEADLRHLKEKVYAGADFIITQLFFRPETFLKFMKDCQAIGITCPIIPGIFP
IQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGVELAVSMCRELLDSGMVHGL
HFYTLNREVATTEVLKRLGIWNEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRT
QEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFTCY
ITGEPNRNGYKVTCMPWNDDPLATETNLLKDQLEKVNRRGILTINSQPNINGKPSTDPIV
GWGPSGGYVFQKAYLEFFTSSEIVRALLKVLRKYELRVNYHIVNVKGENITNAPDLQPNA
VTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKLYEEESPSRMIIQYIHDNYYL
VNLVDNDFPLENCLWQVVEDTFELLNSPPQQ
>A0A8E0FR85|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Escherichia coli 97.0246|TrEMBL
MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>A0A2M8U6K4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Ferrovibrio sp|TrEMBL
MTTLTEPNAHAARRSGPLKVSFEFFPPKSAEMEESLWRSVTRLAPLGPRFVSVTYGAGGS
TRERTHNTVVRILNETGLKPAAHLTCVGAAKGEVDEVAQHYWQAGIRHIVALRGDAPEGS
GGFQAHPRGYANSTELIAGLKKIADFEVSVGCYPEGHPDTASPRVELEHLKRKVDAGATR
CITQYFFDTDVYFRFLDRARSAGITVPIVPGILPVTNFRQVVKFSAACGASVPAWMADQF
DGLDDDPETRRMVAAHLAAEQCRRLLAAGIDEFHFYTLNRADLTYAICHVLGVRPKPAIA
GEAAA
>A0A093ETQ1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Tyto alba|TrEMBL
MVNETQHTCSASSSSKSDGGSSSGSESSKDSSRCSTPVLDADRHERLREKMRRRQDSGDK
WFSLEFFPPRTANAAVNLISRFDRMGVGGPLFIDVTWHPAGDPGSDKETSSMIIANTAVN
YCGLETILHMTCCNQTKDDITGHLQKAKRLGLKNIMALRGDPVGEEWEEEVDGFNYAVDL
VKHIRNEFDDYFDICVAGYPKGHPEAESYEADLRHLKEKVLAGADFIITQLFFRPETFLK
FMKDCQAIGITCPIIPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYG
VELAVTMCRELLDSGMVHGLHFYTLNREVATTEVLKRLGIWKEDPRRPLPWAVSAHPKRR
VEDVRPIFWASRPKSYIYRTQEWDDFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELL
KMWGEELTGEESVFEVFTCYITGEPNKNGHKVTCMPWNDDPLATETNLLKEQLEKVNRRG
ILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSEIVTALLKVLKKYELRVNY
HIVNVKGQNITNAPDLQPNAVTWGIFPGREIIQPTVVDPVSFLSWKDEAFALWIEQWAKL
YEEESPSRMIIQYIHDNYYLVNLVDNDFPLENCLWQVVDDTFELLN
>R6H5F9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Firmicutes bacterium CAG:137|TrEMBL
MSVSDILETRNAFSFEVFPPKTDVGMEKLCGEGGVLDQLYTLNPDYISCTYGAGGTNVGK
NLEVLKKIQSDGKCIPVTHFTCIGNTKEGIKEQLQTYLDNGIDHMLALRGDLPFGWTGTG
GDLHYATELVKFVRQEFGDKFTIAVAGSPEGHIACRSLEADIAFLKQKQDNGADYIMTQL
CWDMDQFRYWLDAIRAAGIWMPVDVGIMPILDQAATINMALSRNGCVMPRELCEIISKNW
IFPNPFDKEPFDANAAEKKASFKEAGIEYTIRQIDEYRACGINGIHLYALNKFDDVARIA
REAGLLDLI
>K2C9Y4|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MSSPHLSFEFFPPKTTAGINALLQTAGMLTAINPSYFSVTFGAAGSAQTHTPDTVFKIKK
HTRIQTAPHISCVAAEKENIKNLLDRYIQKDISRLVVLRGDAPANTTIPSTHFQHASELV
QFIREQTGNHFHIDVACYPEFHPQTTDVKRALFHLKEKMDAGANSMITQYFYNPDAYFRF
RDDCEKFHITAPITPGIMPIIHYEKLVSFSNACGAEIPRWLKFRLENYKNDIISLHTFCD
DVLTDLCEKLLSGGASGLHFYTLNKSEYCLNILKNLKINPVFA
>A0A2T5Y910|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Sphingobacterium faecium (strain DSM 11690 / JCM 21820 / NBRC 15299 / NCIMB 13408 / KS 0470)|TrEMBL
MKIVDHISNAKGKTLFSFELLPPAKGQGIQSIFKTMDALMEFKPPFIDVTYHREDYMYKK
HESGLLERVAYRKRPGTVAICAAIMNKYKVDAVPHLICGGFTKEETENALIDLNFLGIDN
VLVLRGDARKGDSDFIPTDGGHAFATDLLQQVVDMNQGQYLHEDIAISEKTNFCIGVAGY
PEKHFEAPNFNTDFKWLKKKVEMGAEFIVTQMFFNVEKYKEFVTKCRENGIHVPIIPGLK
PLTTKKQLITLPKIFHLDIPEELSEAVSACKSNADVRQVGEEWLVQQCKELIDFGAPVLH
FYTMSNPGPTKSIVEKLF
>A0A1Y6JX28|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Levilactobacillus zymae|TrEMBL
MDPAKPELSFEVFPPSSPAGTAKLTQTLAQLKGIAPSFVSVTCSNHQLNYEQSTIALAQA
VHRDLRCATMVHMPAAYVTKAQVRQILDQLEAAHIQQVLALRGDLDGAAPETDFTHASDL
VRFIKRVKPQFRVTGACYPEVHPDSPDRVADIRNLKAKVDAGCDQLITQLFYDNAQFYRF
REACAIAGITVPILAGIMPITNRQQALHVVQNCAASLPPKFRAILDKYRDNPVALREAGL
AYAVDQIVDLVTHDVAGIHLYTLNQAATAQHIYDNTASLFAPVTVAD
>A0A1F5BL63|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Atribacteria bacterium RBG_16_35_8|TrEMBL
MDLREKLTANNFVVTVELDPPKTLNLDKILREVNCDNFRKAVDAVNVTDCPLAKLRMSPI
ALSHIIQEKIGLEAIFHITCRDRNLLGLQAELLGASALGVRNILALTGDPPEVGDYIMAT
GVYDVDSIGLVKMVNRLNNGHEFGEHELKDKTDFFIGVAVNPTAQDLTKEIKRFEEKVSA
GANFIQTQPIYDIGLLERFLKLTAHINIPKIIGIMPLKSYKMVEYLNNNLPGIFVPSGVK
ERMRGMDVEEGIKISREHISEIRKFKEAAGIHIFPLRDMDLVCRLFD
>K2DAH0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MKLKEIYNSKKPVISYEIFPPKGEFPEIEPKIDALFQELKVLSKYNPSFISVTYGAGGST
REKTLELVLKVKNELNIQPLPHFTCVGTEIDQTLEYIKQVQNAGIENILALRGDPPKGET
KFVKPKNGFGYANELVEFIKSHTDLGIAVAGYPEGHQECVSFEQDIVNLKKKVDAGSDVI
ITQLFYDNNYFLNYLDKTQKAGINIPIVPGVMIITNVAQIERMISMCGCTIPDKLMAKLK
EYQDDNKAVREIGIEYAINQCKELLENGVPGLHFCTLNKSFATDSVLKELV
>A0A1B2CTF3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MTASVRELLASSRPTWSFEFFPAKTPEGDAQLWTALRRLESLRPSFVSVTYGAGGSTREG
TVAVTERIAAETTMTPLAHLTAVDHSVAELRHVVSRLAAAGVRNLLALRGDPPGADPQAD
WIAHPQGLHYASELVELIRSMGDFSVGVAAFPERHPRSPDLDTDVEMFVRKCRAGADFAI
TQMFFRVEDYLRLRDRVAARGCDVPLIAGVMPVTNARQITRIVQLSGQAFPEDLAARFAE
LDGDSPEARAAVRAYGVEVATAMCRRLLDEGVPGIHFITMNRSTATREVHANLTDATTGT
SVPSTLAATP
>K1YED1|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|uncultured bacterium|TrEMBL
MELKTKSKLEKIFKSGQMAVTSECGPPRSSDPEHIIKKGHIIKNHVDAINITDNQTSVTR
LCSLAACIHLKLEGMEPVLQMVVRDRNRIALQSDILGAASFGINNMLCLTGDHQSFGDHP
KAQNVFDLDSMQLIQTVRHMRDEGKFLGGEEIKVPPNLFVGAAANPFADPFKIRVPRLAK
KIAAGAEFIQTQCVYNLEKFELWMKGVVERGLHEKVFIMPGITPMRSVGMAKYMARAVPG
MDVPDDLIKRMSGVPKDKQAAEGITIAVEAIQRLKEVKGVSGFHIMAIEWEEKVPEIVER
AGLYPRPKVD
>A0A7S8IST9|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Qipengyuania soli|TrEMBL
MSPTVDQMREAQRALETPLFSGLPGDIEVSFEFFPPKTEKMGETLWHAVETLKPLGPRFA
SVTYGAGGSTRERTHQQVVRIQNEAGIPAAAHLTCVEATREEVDEVARHYWEEGIRHIVA
LRGDPPDGSGNYTPHPGGYANAVELITGLKKIADFEISVAAYPEVHPDSPDAQADIANLK
AKFDAGATRAITQFFFDPQCFFRFRDEAARAGIEGEIVPGIMPVLSFAAVQRMSGLCGTA
IPSWMEGLFEGLDDRPEARQLVSATIAAELCRRLYAGGVRQFHFYTLNRAELSYAICHML
GLRPKA
>A0A6P0KDE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Symploca sp. SIO3C6|TrEMBL
MSNAIQNSKSQIATETVSLSNYLQDTTPTKNSFRHAAESGKFLITAEVTPPKGGNPAQMV
KMAKTLKGRVHAVNITDGSRAVLRMSSLAASVILLQQGLEPICQLACRDRNRIALQADLM
GANALGICNILALTGDPVKAGDHPEAKSVFDLESVRLLQLISKLNQGVDAHDKPLTDDVT
DLFAGAAVDPQLKSWSGLQRRFERKIEAGAQFFQSQLITDFERLEKFMDEIAAGSNKPIL
AGIFLLKSAKNARFINKYVPGVNIPEAIIERLAAAKEPLLEGMNIAAEQVQIAQQICQGV
HMMAVKREDLIPQILDLAGVEALHN
>A0A522XZG8|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Nitrosotenuis sp|TrEMBL
MLIRYEINPPRVIQEKVLSHKEVQSSLDKLKKRIFEISRYCGGIHLTDSVLGIPRISPIT
TGALIRNDGLNLNITASLRVRDRNLISLTQSVYDAVLLGLDGLLILKGDEPPEGPKDSKL
APSGVVKYFKDLGFGKNLDFYLSVSADPDFEKIQKKIDVAPTGFVTQVIQAPEQVFRIVD
RLKPQGFKIIPVIMVPSEKNAKSFSMLGIDYTKYKDRFIDFVTEIHRSTGDVLITSPNDF
RAASDMLEQLKELKRN
>A0A4U0EYH6|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Pontimicrobium aquaticum|TrEMBL
MKVTEHLKKANGNTQFSFEILPPLKGQHIQSIFNNIDPLMEFNPPFIDVTYHREEYVYKE
LENGLLKKQVVKKRPGTVGICAAIQNKYSVDAIPHILCGGFTKEDTENFLIDLDFLGIDN
VMALRGDAVKTETYFKAEKEGHNYASELVTQIQELNRGNYLDEELLNSSATNFCVGVAAY
PEKHMEAPSLDSDIHFLKKKIRNGAEYIVTQMFFDNQKYFDFVEKCRKENITVPIIPGLK
PISTKKQLNLIPHRFHVDLPEELIIEVVKCKDNTQVKQIGIEWCIKQSKELKKAGIPVLH
YYSMGKSDNIKSIASQVF
>A0A8E1X2J0|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Lentilactobacillus buchneri|TrEMBL
MSLTALFKQKTVFSLEVFPPKKDSPTDAILPTLKRLQSLQPDFISVTLGAGGTNHCDGTV
AVADLIQNQLNIPAVSHVPGLYQSKDQVLALLDRLDQIHVKNILALRGDRIPGKEPVGDF
NHANELVKFVHEQRPDFSIASACYPNCHTEAADFVDDISHLKEKVAAGADHLISQLFFDN
QAFYDFKEKTEIAGINVPIEAGIMPCTNKNQIERITQISGVPIPKKFAAIMDRYQDSKEA
MLDAGIAFAVDQIIDLVSQGVDGIHLYTMNKSKIAKRIWEETESVFAASNLAKQKANQN
>A0A1X0RHE5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizopus microsporus var. microsporus|TrEMBL
MFYSFEYFPPKTAMGVQNLYDRIERMQRFGPEFIDITWGAGGSSADLTTEIVATTQSVYG
LETMMHLTCTNMPIEKIDKALEAAKQCGCQNILALRGDPPKGQLNWESCENGFNYAIDLV
RYIRDKYGDYFCIAVAGHPEGHIDNPDKDDDLLRLKQKVDAGADLIVTQLFFDVDIFVDF
VKRCRDIGIQCPIIPGLFPIQSYSSLSRVISFNKNHVPQKIWDDLETVKDDDQAVKDYGI
DLTIQFIKRIKQETSISGFHIYTFNLERSSRLILEKLGLVPEQEYVKPLPWNPSLTPTRG
KENVRPIFWKHRTQSYIQRTESWDEFPNGRWGDARSPAFGEFDRWGVSIKYPPEKQLAMW
GTPESVDDIALLFAKYCKGKLEALPWSAQKLDPETDIIKQRLAAINFLGYLTINSQPAVN
GARSSDPVYGWGPRNGYVYQKAYIEFFVSPEQLQVLIDKMSNEPEITYFAVNYKGELKTN
TVYKEPNAVTWGVFPGKEIIQPTIVEETAFMAWKDEAFELWSEWARIYDRKSPSAEIILD
IHDHWYLVNIVHNDFQDEDGIWRLFDLEIDGDLSRRLRRGSGSL
>A0A365TUY7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Roseovarius sp. TE539|TrEMBL
MTKPTVSFEFFPPKSLEGSFRLWDTVHALAPLEPRFVSVTYGAGGTTRTLTRDAVGTLRQ
ATGLDVAAHLTCVDASRAETMAIADEFAASGVKEIVALRGDPPKGTTRFTPHPEGFANSC
ELIGALAERGDFTIRVGAYPETHPEASCAQADIDWLKRKFDAGADEAITQFFFTAESFFR
FRDACEKAGIDRPIVPGILPIENWRGARKFATSCGTRIPAWLDDAFAKAIRDDRHDLLAT
ALATELCGDLIDGGVEQLHFYTLNRPDLTRDICHALGVVPQVQLRDVA
>A0A2H0IX76|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Comamonadaceae bacterium CG12_big_fil_rev_8_21_14_0_65_59_15|TrEMBL
MTASPRFPISVEFFPPKTPEGVDKLRAVRQQLYALKPEFCSVTFGAGGSTQEGTFSTVAA
ILSEGVAAASHISCIGATHERVREQLATLQTMGVRRLVALRGDLPSGFGTGGEFHYASDL
VAFIRAETGDTFHIEVAAYPEMHPQAKSPESDVKAFAAKVQAGADSAITQYFYNPDAYFR
FIEDADALGVRVPVVPGIMPIASSSQLMRFSDACGAEIPRWIRLRLQSLGDDSASIKAFG
LDVVTSLCEQLRAGGAPGLHFYTMNQSAAVLEICKRLGV
>A0A177QG03|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Rhizomicrobium sp. SCGC AG-212-E05|TrEMBL
MSLERLITDPSPLQVSFEFSPPKTDEAEANLWTAIRRLEPLQPSFVSVTYGAGGSTRERT
HATVKRIVEETTLKPAAHLTCVGASRGETDDILRAYWDAGIRHIVALRGDMPNMTGPYQP
HAEGYRSTPELIAGIKKIADFEVSVSFYPERHPDSPSHGHDVELLKAKMDAGASRALGQF
CFDNDVTARFRDDALAAGITIPVVPGVMPTTNFNGIARMAGKAGASIPAWLAKAYEGLDE
DVETRRIVAAAVLSDQVRQLRRRGFGQFHFYTLNQANLTYAACRILGLRPKDLS
>X5U9D3|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Mesorhizobium sp. LSHC426A00|TrEMBL
MNQFRFSRRPDIGDKVRVSFEFFPPKTDEMEARLWDTVTRLEPLKPRFVSVTYGAGGSTR
ERTARTVKRILNETTLTPAAHMTCVDAARHEVDAVVREFADMGVKRFVALRGDPAAGVGT
AYRPHPDGYANGAELVGALKDAGDFDISVSAYPEKHPESPDFATDFDMLKRKADNGATRA
ITQFFFDNDLYERYVEKARRAGIYIPIVPGILPVHNFTQVANFSARCGALVPAWLAERFE
GLHNDPQTHALVASAVAAEQVLDLVERGVSDFHFYTMNRADLVFAICHMIGIRSHETEAA
GSAAA
>A0A1C3NZT7|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Candidatus Frankia californiensis|TrEMBL
MMDEARAASEDPVFADMPAFRVGAAAGLRPLPAWKRAADFLFVQVSYSVDALLRWRDAHP
VELPVYAGVMVLASAGMARRLAATIPDIDIPDDLVQAVERDQTAGVEAACDQVLRLRDSD
AFAGVHLVPVSRYRQVATRLEDLL
>A0A1F3SK09|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Bdellovibrionales bacterium GWA2_49_15|TrEMBL
MKVIDHINNRKGPLFSFEIVPPPRGRTVQDIFDIINALVPFKPSWIDVTAHSASAYYNER
ADGTVQRRIYKKRPGTIGICGIIQNRFNIDTVGHLLCNGFTKEETEDALIELNFLGVQNI
LAVRGDGLNYKKNIAKDRSVNLYASDLVSQMSSIKRGLYLDELSLARPLNFCVGVAGYPE
KHFESPSLKQDLFYLKKKVELGAEYIMTQMFFDNQKYFDFVAACRAEGITVPIIPGIKIL
KTKNQLQSIPSNFYIDLPDELVEEALKNPEHIPAIGIRWAQQQVEGLLKADVPDVHFYIM
NDTELVVDVIKKFRQ
>A0A1F4M9R5|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Burkholderiales bacterium RIFOXYD12_FULL_59_19|TrEMBL
MNSTVRFPVSIEFFPPKTPEGVEKLRVVRQQLYALMPEFCSVTFGAGGSTQEGTFSTVRD
ILSEGVSAASHFSCIGATRAGVREQLATLKAMGVKRLVALRGDLPSGYGTGGEFHYASDL
VAFIRAEMSDDFYIEVAAYPEIHPQAKSAESDLKAFAAKAQAGANSAITQYFYNSDAYFR
FVEDADALGVQIPVVPGIMPIASSSQLMRFSDACGAEIPRWIRLRLLGFGDDTASIKAFG
LDVVTDLCEQLRAGGAPGLHFYSMNQSAATLEICQRLGLAA
>A0A561WJ29|methylenetetrahydrofolate reductase [NAD(P)H]|EC 1.5.1.20|Actinoplanes teichomyceticus|TrEMBL
MSLGLPSKLPGTPSIGELVRGAAPTFSFEFFPPKTPDGERLLWQAIRELESLRPSFVSIT
YGAGGTTRETTVAVTERVATETTLLAMAHLTAVDHSVADLRNVIGRLAGAGIRNVLALRG
DPPGDPMGEWVRHPDGVLYAAELVSLIRESGDFSVGVAAFPYKHPRSADVAGDTRHFIRK
CRAGAEYAITQMFFDADDYLRLRDRVAAAGCDTPIVAGVMPVTRMATIERSTQLSGAPFP
PQLLRRFERVAGDEAAVRELGIETCSQMCARLLEEGVPGIHFITMNRSTATREVWQRLAP
SEVAAAG